# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- HSP90 PF00183.13 CBZ49503.1 - 3.9e-72 243.3 1.6 7.1e-71 239.2 0.4 2.0 1 1 1 2 2 2 2 Hsp90 protein HATPase_c_3 PF13589.1 CBZ49503.1 - 8.8e-12 44.8 0.1 1.7e-11 43.9 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 CBZ49503.1 - 1.8e-06 27.6 0.0 3.7e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase BRE1 PF08647.6 CBZ49504.1 - 0.0018 18.2 8.0 0.0018 18.2 5.5 8.9 3 3 4 8 8 8 1 BRE1 E3 ubiquitin ligase V_ATPase_I PF01496.14 CBZ49505.1 - 0.55 8.0 0.8 0.83 7.4 0.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family IncA PF04156.9 CBZ49505.1 - 0.63 9.6 13.3 0.016 14.8 1.6 2.5 2 0 0 2 2 2 0 IncA protein DUF342 PF03961.8 CBZ49505.1 - 8.3 4.7 9.4 0.71 8.2 3.2 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF342) Ribonuc_red_sm PF00268.16 CBZ49507.1 - 3.4 6.5 0.0 5.6 5.8 0.0 1.2 1 0 0 1 1 1 0 Ribonucleotide reductase, small chain PDEase_I PF00233.14 CBZ49508.1 - 1.7e-46 158.9 7.3 1.3e-26 93.8 2.5 2.2 2 0 0 2 2 2 2 3'5'-cyclic nucleotide phosphodiesterase GAF_3 PF13492.1 CBZ49508.1 - 1.8e-07 31.3 0.0 5e-05 23.4 0.0 2.9 2 0 0 2 2 2 2 GAF domain DUF964 PF06133.6 CBZ49511.1 - 0.1 12.6 0.1 0.16 12.0 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF964) DUF1469 PF07332.6 CBZ49511.1 - 2.9 7.6 6.7 6.1 6.5 4.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1469) Sybindin PF04099.7 CBZ49512.1 - 2e-44 150.7 0.0 2.2e-44 150.6 0.0 1.0 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.8 CBZ49512.1 - 6.6e-08 32.4 0.0 1.2e-07 31.6 0.0 1.4 2 0 0 2 2 2 1 Sedlin, N-terminal conserved region SPRY PF00622.23 CBZ49513.1 - 3.1e-16 59.6 0.0 6.6e-16 58.5 0.0 1.6 1 0 0 1 1 1 1 SPRY domain CLTH PF10607.4 CBZ49513.1 - 1.6e-11 44.1 0.1 1.7e-10 40.8 0.0 2.1 2 0 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain HEAT PF02985.17 CBZ49513.1 - 0.0083 16.1 0.1 0.031 14.3 0.1 1.9 1 0 0 1 1 1 1 HEAT repeat RE_AccI PF09545.5 CBZ49514.1 - 5.4 5.4 0.1 17 3.8 0.0 1.7 2 0 0 2 2 2 0 AccI restriction endonuclease ELFV_dehydrog PF00208.16 CBZ49515.1 - 2.8e-83 279.2 0.1 3.6e-83 278.8 0.1 1.1 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.13 CBZ49515.1 - 3.8e-47 159.1 0.0 7e-47 158.2 0.0 1.5 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain Exo_endo_phos PF03372.18 CBZ49516.1 - 2.5e-17 63.6 0.0 5e-17 62.6 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family CDO_I PF05995.7 CBZ49516.1 - 0.034 13.3 0.0 0.06 12.5 0.0 1.3 1 0 0 1 1 1 0 Cysteine dioxygenase type I MMgT PF10270.4 CBZ49517.1 - 5.7e-08 33.1 0.0 6.7e-08 32.9 0.0 1.0 1 0 0 1 1 1 1 Membrane magnesium transporter DUF3995 PF13160.1 CBZ49517.1 - 0.035 14.1 0.8 0.044 13.8 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3995) CitMHS PF03600.11 CBZ49517.1 - 0.1 11.1 0.0 0.12 10.9 0.0 1.1 1 0 0 1 1 1 0 Citrate transporter zf-DHHC PF01529.15 CBZ49518.1 - 3.3e-36 124.2 11.4 1.6e-35 122.0 8.4 1.7 2 0 0 2 2 2 1 DHHC palmitoyltransferase DUF2465 PF10239.4 CBZ49519.1 - 4e-45 154.4 0.0 5.8e-45 153.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2465) Abhydrolase_6 PF12697.2 CBZ49520.1 - 4.1e-11 43.1 2.5 4.6e-11 43.0 0.4 2.1 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydro_lipase PF04083.11 CBZ49520.1 - 2.7e-07 29.8 0.0 5.6e-05 22.4 0.0 2.6 2 0 0 2 2 2 2 Partial alpha/beta-hydrolase lipase region Abhydrolase_5 PF12695.2 CBZ49520.1 - 1.1e-06 28.4 0.1 0.63 9.7 0.0 3.2 3 0 0 3 3 3 3 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CBZ49520.1 - 3.1e-05 23.6 0.0 0.13 11.8 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold DLH PF01738.13 CBZ49520.1 - 0.036 13.3 0.0 0.063 12.5 0.0 1.3 1 0 0 1 1 1 0 Dienelactone hydrolase family BAAT_C PF08840.6 CBZ49520.1 - 0.047 13.4 0.0 0.57 9.8 0.0 2.0 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Macoilin PF09726.4 CBZ49521.1 - 1.8 6.7 3.6 3.1 5.9 2.5 1.3 1 0 0 1 1 1 0 Transmembrane protein HATPase_c PF02518.21 CBZ49524.1 - 1.4e-09 37.6 0.0 1.7e-08 34.1 0.0 2.4 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase BCDHK_Adom3 PF10436.4 CBZ49524.1 - 0.017 14.6 0.0 0.03 13.8 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c_3 PF13589.1 CBZ49524.1 - 0.049 13.2 0.0 0.26 10.9 0.0 2.0 1 1 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Cyclin PF08613.6 CBZ49525.1 - 4.3e-24 85.6 0.0 8.2e-24 84.7 0.0 1.4 1 0 0 1 1 1 1 Cyclin WW PF00397.21 CBZ49526.1 - 2.6e-08 33.5 5.4 6e-08 32.4 3.8 1.7 1 0 0 1 1 1 1 WW domain Yip1 PF04893.12 CBZ49526.1 - 2e-07 30.6 13.0 1e-06 28.3 9.2 1.8 1 1 1 2 2 2 1 Yip1 domain YIF1 PF03878.10 CBZ49526.1 - 0.0015 17.7 0.0 0.042 13.0 0.0 2.1 2 0 0 2 2 2 1 YIF1 Ribosomal_L20 PF00453.13 CBZ49527.1 - 9.8e-31 105.8 1.1 1.1e-30 105.7 0.7 1.0 1 0 0 1 1 1 1 Ribosomal protein L20 DUF179 PF02622.10 CBZ49529.1 - 5.3e-09 35.8 0.0 1.6e-06 27.8 0.0 2.9 3 0 0 3 3 3 2 Uncharacterized ACR, COG1678 Ran_BP1 PF00638.13 CBZ49530.1 - 5.3e-39 133.0 0.8 1.1e-38 132.0 0.6 1.5 1 0 0 1 1 1 1 RanBP1 domain WH1 PF00568.18 CBZ49530.1 - 0.03 14.0 1.9 0.18 11.5 1.3 2.0 1 1 0 1 1 1 0 WH1 domain AhpC-TSA PF00578.16 CBZ49530.1 - 0.04 13.6 0.8 0.076 12.7 0.6 1.4 1 0 0 1 1 1 0 AhpC/TSA family Mito_carr PF00153.22 CBZ49531.1 - 9.3e-43 143.8 0.0 2.6e-16 59.0 0.0 3.7 3 1 0 3 3 3 3 Mitochondrial carrier protein Met_10 PF02475.11 CBZ49533.1 - 2e-05 24.3 0.0 3.2e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_18 PF12847.2 CBZ49533.1 - 3.5e-05 24.3 1.1 0.0001 22.8 0.1 2.3 2 1 0 2 2 2 1 Methyltransferase domain PrmA PF06325.8 CBZ49533.1 - 0.00055 19.1 0.0 0.00095 18.3 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_26 PF13659.1 CBZ49533.1 - 0.0067 16.4 1.7 0.01 15.8 0.3 2.1 2 1 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 CBZ49533.1 - 0.011 15.1 0.0 0.024 14.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain TehB PF03848.9 CBZ49533.1 - 0.077 12.1 0.0 0.13 11.4 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB Hat1_N PF10394.4 CBZ49535.1 - 6.1e-32 110.9 0.0 1e-31 110.2 0.0 1.4 1 0 0 1 1 1 1 Histone acetyl transferase HAT1 N-terminus Cyto_heme_lyase PF01265.12 CBZ49536.1 - 2.4e-62 210.8 0.6 2.4e-62 210.8 0.4 2.0 2 0 0 2 2 2 2 Cytochrome c/c1 heme lyase DUF1375 PF07119.7 CBZ49538.1 - 0.089 12.6 0.0 0.11 12.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1375) MFS_1 PF07690.11 CBZ49539.1 - 3.5e-14 52.3 15.7 3.5e-14 52.3 10.9 1.9 2 1 0 2 2 2 1 Major Facilitator Superfamily MFS_1 PF07690.11 CBZ49540.1 - 7.5e-16 57.7 9.4 7.5e-16 57.7 6.5 2.5 2 1 0 2 2 2 2 Major Facilitator Superfamily HemY_N PF07219.8 CBZ49541.1 - 0.082 12.4 0.9 0.86 9.1 0.0 2.6 2 0 0 2 2 2 0 HemY protein N-terminus DUF2207 PF09972.4 CBZ49541.1 - 0.13 10.8 2.2 0.2 10.1 1.5 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF1516 PF07457.6 CBZ49541.1 - 1.3 9.1 9.3 0.15 12.1 3.6 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1516) Shisa PF13908.1 CBZ49542.1 - 0.0049 17.0 1.1 3.4 7.8 0.4 2.6 2 0 0 2 2 2 2 Wnt and FGF inhibitory regulator CbiQ PF02361.11 CBZ49542.1 - 0.0094 15.5 1.8 0.013 15.0 1.2 1.2 1 0 0 1 1 1 1 Cobalt transport protein VIT1 PF01988.14 CBZ49542.1 - 0.014 14.9 0.2 0.014 14.9 0.2 1.6 2 0 0 2 2 2 0 VIT family DUF4448 PF14610.1 CBZ49542.1 - 0.04 13.4 8.6 0.19 11.1 0.2 3.2 3 1 0 3 3 3 0 Protein of unknown function (DUF4448) DUF4519 PF15012.1 CBZ49542.1 - 2.4 8.1 5.6 0.29 11.0 0.5 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4519) PP2C PF00481.16 CBZ49543.1 - 1.2e-44 152.6 0.0 1.6e-44 152.2 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 CBZ49543.1 - 1.1e-06 28.5 0.1 0.0016 18.1 0.0 2.2 2 0 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.1 CBZ49543.1 - 1.4e-06 27.8 0.0 1.2e-05 24.7 0.0 2.3 1 1 0 1 1 1 1 Protein phosphatase 2C DNA_ligase_A_N PF04675.9 CBZ49544.1 - 1.2e-26 93.5 0.0 2e-26 92.8 0.0 1.4 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 CBZ49544.1 - 2.7e-16 59.7 0.0 1.2e-15 57.7 0.0 2.2 2 0 0 2 2 2 1 ATP dependent DNA ligase C terminal region DNA_ligase_A_M PF01068.16 CBZ49544.1 - 2.7e-15 56.2 0.0 7.9e-09 35.1 0.0 2.4 2 0 0 2 2 2 2 ATP dependent DNA ligase domain BRCT PF00533.21 CBZ49544.1 - 2.6e-06 27.4 0.0 1.4e-05 25.1 0.0 2.1 1 1 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 CBZ49544.1 - 0.0043 16.8 0.0 0.011 15.5 0.0 1.7 1 0 0 1 1 1 1 twin BRCT domain MoeA_N PF03453.12 CBZ49546.1 - 1.5e-23 82.9 0.5 3e-15 55.9 0.0 2.4 2 0 0 2 2 2 2 MoeA N-terminal region (domain I and II) MoCF_biosynth PF00994.19 CBZ49546.1 - 3.2e-23 81.7 0.0 3e-08 33.1 0.0 5.7 4 3 0 4 4 4 3 Probable molybdopterin binding domain MoeA_C PF03454.10 CBZ49546.1 - 6.6e-05 22.7 0.0 0.0033 17.3 0.0 2.7 2 0 0 2 2 2 1 MoeA C-terminal region (domain IV) zf-PARP PF00645.13 CBZ49549.1 - 5.6e-14 52.1 0.6 2.6e-13 50.0 0.4 2.2 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region PADR1 PF08063.7 CBZ49549.1 - 2.9e-09 36.1 0.1 2.9e-09 36.1 0.1 1.8 2 0 0 2 2 2 1 PADR1 (NUC008) domain SAP PF02037.22 CBZ49549.1 - 5e-06 25.8 0.3 9.7e-06 24.9 0.2 1.4 1 0 0 1 1 1 1 SAP domain TF_Zn_Ribbon PF08271.7 CBZ49549.1 - 0.021 14.1 1.0 0.021 14.1 0.7 2.0 2 0 0 2 2 2 0 TFIIB zinc-binding Sec62 PF03839.11 CBZ49553.1 - 2e-24 86.2 8.4 2e-24 86.2 5.8 1.6 2 0 0 2 2 2 1 Translocation protein Sec62 DUF2207 PF09972.4 CBZ49553.1 - 0.7 8.4 2.8 1 7.8 2.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Prefoldin_2 PF01920.15 CBZ49554.1 - 3.1e-18 65.4 1.5 3.9e-18 65.1 1.0 1.1 1 0 0 1 1 1 1 Prefoldin subunit BicD PF09730.4 CBZ49554.1 - 0.029 12.7 0.1 0.029 12.7 0.1 1.3 2 0 0 2 2 2 0 Microtubule-associated protein Bicaudal-D Cep57_CLD PF14073.1 CBZ49554.1 - 1 9.1 6.7 3.5 7.4 3.6 2.0 1 1 1 2 2 2 0 Centrosome localisation domain of Cep57 ketoacyl-synt PF00109.21 CBZ49555.1 - 1.4e-54 185.2 1.7 2.5e-54 184.4 0.8 1.7 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 CBZ49555.1 - 2.9e-38 130.3 1.4 4.3e-38 129.8 0.3 1.8 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.18 CBZ49555.1 - 0.056 12.4 0.1 0.11 11.5 0.1 1.4 1 0 0 1 1 1 0 Thiolase, N-terminal domain Ribosomal_L27 PF01016.14 CBZ49556.1 - 4.8e-28 96.7 0.1 7.6e-28 96.1 0.1 1.3 1 0 0 1 1 1 1 Ribosomal L27 protein Amidohydro_2 PF04909.9 CBZ49557.1 - 9.2e-11 41.8 0.4 2.7e-10 40.2 0.0 1.9 2 1 0 2 2 2 1 Amidohydrolase Amidohydro_3 PF07969.6 CBZ49557.1 - 0.036 13.2 0.1 1.1 8.4 0.0 2.1 2 0 0 2 2 2 0 Amidohydrolase family DUF3546 PF12066.3 CBZ49559.1 - 8.6e-11 41.8 6.2 1.7e-10 40.8 4.3 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3546) ARS2 PF04959.8 CBZ49559.1 - 1.8e-06 28.2 0.8 5.8e-06 26.6 0.0 2.1 2 0 0 2 2 2 1 Arsenite-resistance protein 2 DUF4187 PF13821.1 CBZ49559.1 - 7.1e-06 25.5 0.3 2.2e-05 23.9 0.2 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) IcmL PF11393.3 CBZ49559.1 - 0.027 14.4 0.3 0.05 13.5 0.2 1.3 1 0 0 1 1 1 0 Macrophage killing protein with similarity to conjugation protein zf-C2H2 PF00096.21 CBZ49559.1 - 0.097 13.0 3.4 0.24 11.7 2.3 1.8 1 0 0 1 1 1 0 Zinc finger, C2H2 type TFIIS_M PF07500.9 CBZ49561.1 - 1.3e-28 99.4 0.1 2e-28 98.7 0.1 1.3 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.13 CBZ49561.1 - 2e-18 65.7 5.9 4.6e-18 64.5 4.1 1.6 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Med26 PF08711.6 CBZ49561.1 - 8.5e-15 54.0 0.1 1.6e-14 53.0 0.1 1.5 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Profilin PF00235.14 CBZ49563.1 - 1e-12 48.2 0.5 1.7e-12 47.5 0.3 1.3 1 1 0 1 1 1 1 Profilin WD40 PF00400.27 CBZ49564.1 - 2.6e-16 58.8 12.4 0.00017 21.3 0.8 6.5 6 0 0 6 6 6 4 WD domain, G-beta repeat zf-RanBP PF00641.13 CBZ49565.1 - 3.7e-07 29.1 21.7 0.00067 18.7 5.9 2.7 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others DZR PF12773.2 CBZ49565.1 - 0.012 15.4 15.5 0.31 10.8 2.9 2.9 3 0 0 3 3 3 0 Double zinc ribbon PHD PF00628.24 CBZ49565.1 - 0.13 11.9 5.5 4.2 7.1 0.5 3.4 3 0 0 3 3 3 0 PHD-finger FUR PF01475.14 CBZ49565.1 - 0.69 9.8 4.3 2 8.3 0.1 2.3 1 1 1 2 2 2 0 Ferric uptake regulator family DUF35_N PF12172.3 CBZ49565.1 - 0.82 9.6 16.9 4.8 7.2 2.0 3.0 2 0 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) zinc-ribbons_6 PF07191.7 CBZ49565.1 - 7.8 6.3 9.7 0.75 9.6 1.3 2.3 2 0 0 2 2 2 0 zinc-ribbons HAD_2 PF13419.1 CBZ49566.1 - 0.00019 21.6 0.2 0.075 13.2 0.0 2.5 1 1 1 2 2 2 2 Haloacid dehalogenase-like hydrolase Dendrin PF15498.1 CBZ49566.1 - 0.067 11.6 0.0 0.086 11.3 0.0 1.1 1 0 0 1 1 1 0 Nephrin and CD2AP-binding protein, Dendrin Pkinase PF00069.20 CBZ49567.1 - 3.7e-18 65.6 0.0 7.5e-14 51.4 0.0 2.2 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ49567.1 - 4.3e-09 35.8 0.0 9.5e-09 34.6 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBZ49567.1 - 0.00037 19.5 0.0 0.00062 18.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 CBZ49567.1 - 0.0071 16.1 0.1 0.014 15.1 0.1 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family MFS_1 PF07690.11 CBZ49568.1 - 1e-19 70.4 29.0 2.2e-15 56.2 10.2 2.4 2 1 0 2 2 2 2 Major Facilitator Superfamily RRM_1 PF00076.17 CBZ49569.1 - 2e-17 62.5 0.0 2.8e-17 62.0 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBZ49569.1 - 3.1e-12 46.3 0.0 4.5e-12 45.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBZ49569.1 - 1.7e-10 40.6 0.2 2.3e-10 40.1 0.1 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WW PF00397.21 CBZ49569.1 - 8.8e-07 28.6 0.9 8.8e-07 28.6 0.6 1.9 2 0 0 2 2 2 1 WW domain CTNNBL PF08216.6 CBZ49571.1 - 5.4e-31 106.3 3.0 3e-30 103.9 2.0 2.4 1 0 0 1 1 1 1 Catenin-beta-like, Arm-motif containing nuclear Arm PF00514.18 CBZ49571.1 - 0.021 14.6 0.9 0.11 12.3 0.0 2.7 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 CBZ49571.1 - 0.055 13.7 3.2 0.65 10.3 0.0 3.3 4 0 0 4 4 4 0 HEAT repeats Pkinase PF00069.20 CBZ49572.1 - 9.6e-20 70.8 0.0 4.9e-09 35.7 0.0 3.1 3 0 0 3 3 3 2 Protein kinase domain Cyclin_N PF00134.18 CBZ49572.1 - 2.8e-05 23.6 1.0 0.00065 19.2 0.0 2.7 3 0 0 3 3 3 1 Cyclin, N-terminal domain Pkinase_Tyr PF07714.12 CBZ49572.1 - 8e-05 21.8 0.0 0.59 9.1 0.0 3.1 2 1 0 2 2 2 2 Protein tyrosine kinase CAP PF00188.21 CBZ49573.1 - 9.7e-11 42.2 0.2 1.4e-10 41.7 0.1 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family CBS PF00571.23 CBZ49575.1 - 6.5e-07 29.0 0.5 2.9e-06 26.9 0.0 2.3 3 0 0 3 3 3 1 CBS domain Sugar-bind PF04198.8 CBZ49575.1 - 0.16 10.8 0.0 0.72 8.6 0.0 1.8 2 0 0 2 2 2 0 Putative sugar-binding domain DnaJ PF00226.26 CBZ49576.1 - 9.3e-18 63.7 0.0 1.6e-17 62.9 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain HeH PF12949.2 CBZ49576.1 - 0.019 14.5 0.2 0.044 13.3 0.0 1.7 2 0 0 2 2 2 0 HeH/LEM domain Armet PF10208.4 CBZ49576.1 - 0.024 14.3 0.0 0.049 13.2 0.0 1.5 1 0 0 1 1 1 0 Degradation arginine-rich protein for mis-folding zf-DHHC PF01529.15 CBZ49577.1 - 2.4e-26 92.1 9.3 2.4e-26 92.1 6.4 1.9 2 0 0 2 2 2 1 DHHC palmitoyltransferase Ank_2 PF12796.2 CBZ49577.1 - 9.7e-22 77.1 0.1 3e-10 40.3 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 CBZ49577.1 - 2e-21 75.9 0.3 1.3e-07 31.9 0.0 3.8 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.25 CBZ49577.1 - 7.1e-18 63.4 0.2 7.5e-08 31.8 0.1 4.5 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.1 CBZ49577.1 - 1.2e-14 52.9 1.8 0.00065 19.7 0.0 5.1 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.1 CBZ49577.1 - 1e-12 47.8 1.7 2.5e-06 27.5 0.0 4.2 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Anp1 PF03452.9 CBZ49577.1 - 0.33 10.0 0.0 0.53 9.3 0.0 1.2 1 0 0 1 1 1 0 Anp1 PSI PF01437.20 CBZ49577.1 - 0.41 10.8 9.0 0.038 14.1 2.4 2.1 2 0 0 2 2 2 0 Plexin repeat EF-hand_1 PF00036.27 CBZ49579.1 - 2.1e-15 54.7 8.5 0.0047 16.1 0.0 5.4 6 0 0 6 6 6 4 EF hand EF-hand_7 PF13499.1 CBZ49579.1 - 5.2e-15 55.3 3.8 2.1e-07 30.9 0.0 4.2 3 1 0 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.1 CBZ49579.1 - 1.3e-12 46.4 8.6 0.035 13.9 0.1 5.5 6 0 0 6 6 6 4 EF-hand domain EF-hand_8 PF13833.1 CBZ49579.1 - 1.4e-11 43.8 7.3 0.0064 16.0 0.1 4.7 4 1 0 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.1 CBZ49579.1 - 3.9e-08 32.2 12.6 0.0021 17.3 0.0 5.2 6 0 0 6 6 6 3 EF hand SPARC_Ca_bdg PF10591.4 CBZ49579.1 - 0.00089 19.2 0.3 3.1 7.8 0.0 3.4 3 1 0 3 3 3 2 Secreted protein acidic and rich in cysteine Ca binding region Excalibur PF05901.6 CBZ49579.1 - 4.4 7.7 6.2 4.6 7.6 0.0 3.4 4 0 0 4 4 4 0 Excalibur calcium-binding domain Glyco_hydro_19 PF00182.14 CBZ49580.1 - 7.3e-10 38.9 0.6 3.6e-09 36.6 0.4 2.2 1 1 0 1 1 1 1 Chitinase class I DUF2067 PF09840.4 CBZ49581.1 - 0.036 13.5 0.7 14 5.1 1.4 2.5 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2067) HeLo PF14479.1 CBZ49581.1 - 0.32 10.7 4.9 0.35 10.5 2.2 1.8 1 1 1 2 2 2 0 Prion-inhibition and propagation DUF2453 PF10507.4 CBZ49583.1 - 1.2e-29 102.3 0.7 1.6e-29 101.9 0.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2453) PepSY_TM_2 PF13703.1 CBZ49583.1 - 0.046 13.8 0.3 0.076 13.2 0.2 1.4 1 0 0 1 1 1 0 PepSY-associated TM helix DUF1072 PF06380.6 CBZ49583.1 - 0.21 11.2 0.4 0.21 11.2 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1072) DUF456 PF04306.8 CBZ49583.1 - 0.27 11.2 4.4 3.6 7.6 0.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF456) PEP_mutase PF13714.1 CBZ49584.1 - 7.4e-56 189.0 0.1 8.7e-56 188.7 0.1 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.16 CBZ49584.1 - 1.2e-18 66.6 0.4 1.8e-18 66.0 0.2 1.2 1 0 0 1 1 1 1 Isocitrate lyase family Peptidase_C2 PF00648.16 CBZ49585.1 - 1.2e-35 122.9 0.0 1.2e-34 119.7 0.0 2.1 1 1 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.17 CBZ49585.1 - 1.1e-13 51.0 0.1 4.7e-10 39.2 0.0 3.6 3 1 0 3 3 3 2 Calpain large subunit, domain III Methyltransf_18 PF12847.2 CBZ49586.1 - 0.00012 22.6 0.0 0.0053 17.3 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 CBZ49586.1 - 0.0029 17.3 0.0 0.0061 16.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_PK PF05891.7 CBZ49586.1 - 0.0032 16.8 0.0 0.0065 15.7 0.0 1.4 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_11 PF08241.7 CBZ49586.1 - 0.005 17.2 0.1 0.018 15.5 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain RrnaAD PF00398.15 CBZ49586.1 - 0.014 14.3 0.0 0.029 13.4 0.0 1.4 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.1 CBZ49586.1 - 0.053 13.8 0.0 0.24 11.7 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain MIP-T3 PF10243.4 CBZ49587.1 - 0.00049 18.6 8.0 0.00049 18.6 5.5 2.4 2 0 0 2 2 2 1 Microtubule-binding protein MIP-T3 Cluap1 PF10234.4 CBZ49588.1 - 1.7e-14 53.6 8.6 1.7e-14 53.6 6.0 1.4 1 1 0 1 1 1 1 Clusterin-associated protein-1 RepA_C PF04796.7 CBZ49588.1 - 0.011 15.2 0.1 0.022 14.3 0.1 1.4 1 0 0 1 1 1 0 Plasmid encoded RepA protein Nup88 PF10168.4 CBZ49588.1 - 3.2 5.4 8.5 4.4 5.0 5.9 1.2 1 0 0 1 1 1 0 Nuclear pore component ERM PF00769.14 CBZ49588.1 - 3.5 7.0 28.2 0.032 13.7 13.9 1.7 2 0 0 2 2 2 0 Ezrin/radixin/moesin family CS PF04969.11 CBZ49589.1 - 1.4e-06 28.7 0.0 3e-06 27.6 0.0 1.6 1 1 0 1 1 1 1 CS domain Thioredoxin PF00085.15 CBZ49590.1 - 3.4e-29 100.5 0.4 3.8e-29 100.4 0.3 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 CBZ49590.1 - 1.6e-06 28.2 0.1 1.3e-05 25.3 0.1 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 CBZ49590.1 - 1.2e-05 25.3 0.0 3.8e-05 23.7 0.0 1.7 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_7 PF13899.1 CBZ49590.1 - 0.00025 21.0 0.0 0.00031 20.6 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_9 PF14595.1 CBZ49590.1 - 0.00063 19.3 0.1 0.00072 19.1 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin AhpC-TSA PF00578.16 CBZ49590.1 - 0.0036 16.9 0.1 0.0041 16.8 0.1 1.2 1 0 0 1 1 1 1 AhpC/TSA family Phosducin PF02114.11 CBZ49590.1 - 0.019 13.6 0.0 0.019 13.6 0.0 1.1 1 0 0 1 1 1 0 Phosducin Redoxin PF08534.5 CBZ49590.1 - 0.057 12.9 0.1 0.1 12.1 0.1 1.5 1 1 1 2 2 2 0 Redoxin Thioredoxin_4 PF13462.1 CBZ49590.1 - 0.095 12.7 0.2 9.6 6.1 0.0 2.1 1 1 1 2 2 2 0 Thioredoxin WD40 PF00400.27 CBZ49591.1 - 4.2e-18 64.4 24.9 7.9e-08 31.8 0.1 7.6 8 1 1 9 9 9 4 WD domain, G-beta repeat eIF2A PF08662.6 CBZ49591.1 - 0.0033 17.1 0.1 0.17 11.5 0.0 3.3 2 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A Apc4_WD40 PF12894.2 CBZ49591.1 - 0.035 13.6 0.0 16 5.1 0.0 4.1 5 0 0 5 5 5 0 Anaphase-promoting complex subunit 4 WD40 domain Sua5_yciO_yrdC PF01300.13 CBZ49593.1 - 1.1e-32 112.7 0.0 1.5e-31 108.9 0.0 2.7 2 1 0 2 2 2 1 Telomere recombination SUA5 PF03481.8 CBZ49593.1 - 4.8e-08 33.1 0.0 1.5e-07 31.4 0.0 1.8 1 1 0 1 1 1 1 Putative GTP-binding controlling metal-binding SID-1_RNA_chan PF13965.1 CBZ49593.1 - 0.14 10.3 0.0 0.21 9.7 0.0 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 zf-RING_2 PF13639.1 CBZ49594.1 - 4.5e-15 55.1 4.9 7.8e-15 54.4 3.4 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 CBZ49594.1 - 4.7e-08 32.5 3.1 7.8e-08 31.8 2.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CBZ49594.1 - 1.3e-07 31.5 5.7 2.2e-07 30.7 4.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 CBZ49594.1 - 3.2e-07 30.3 5.1 7.9e-07 29.0 3.4 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 CBZ49594.1 - 9.6e-06 25.1 2.5 1.6e-05 24.5 1.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBZ49594.1 - 1.4e-05 24.6 3.7 2.4e-05 23.9 2.6 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 CBZ49594.1 - 0.00027 20.5 0.5 0.00067 19.3 0.4 1.7 1 1 0 1 1 1 1 RING-type zinc-finger zf-Apc11 PF12861.2 CBZ49594.1 - 0.0057 16.4 0.9 0.01 15.6 0.6 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger MIP-T3 PF10243.4 CBZ49594.1 - 0.049 12.1 1.7 0.064 11.7 1.2 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 RINGv PF12906.2 CBZ49594.1 - 0.088 12.8 3.2 0.16 12.0 2.3 1.5 1 0 0 1 1 1 0 RING-variant domain zf-C3HC4_4 PF15227.1 CBZ49594.1 - 0.11 12.4 4.5 0.25 11.2 3.1 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING FANCL_C PF11793.3 CBZ49594.1 - 0.26 11.2 2.2 0.58 10.1 1.5 1.6 1 0 0 1 1 1 0 FANCL C-terminal domain Prok-RING_1 PF14446.1 CBZ49594.1 - 0.42 10.3 2.9 1 9.1 2.0 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 Prok-RING_4 PF14447.1 CBZ49594.1 - 1.2 8.7 4.7 2.2 7.9 3.3 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 DUF572 PF04502.8 CBZ49594.1 - 1.5 7.9 7.1 2.8 7.0 4.9 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF572) CDK2AP PF09806.4 CBZ49594.1 - 4 7.6 19.2 7 6.8 13.3 1.4 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein DUF4614 PF15391.1 CBZ49594.1 - 4.9 6.8 22.6 12 5.6 15.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) Macoilin PF09726.4 CBZ49594.1 - 4.9 5.3 24.7 7 4.8 17.1 1.1 1 0 0 1 1 1 0 Transmembrane protein ER_lumen_recept PF00810.13 CBZ49595.1 - 6e-24 85.2 6.1 6e-24 85.2 4.3 2.0 2 0 0 2 2 2 1 ER lumen protein retaining receptor BBE PF08031.7 CBZ49595.1 - 0.096 12.6 0.1 21 5.0 0.0 2.4 2 0 0 2 2 2 0 Berberine and berberine like Methyltransf_4 PF02390.12 CBZ49598.1 - 4.5e-48 162.9 0.0 5.6e-48 162.6 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 CBZ49598.1 - 0.0015 19.0 0.0 0.0028 18.2 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CBZ49598.1 - 0.004 17.5 0.0 0.0082 16.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 CBZ49598.1 - 0.0079 16.2 0.0 0.015 15.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CBZ49598.1 - 0.011 16.1 0.0 0.016 15.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain DOT1 PF08123.8 CBZ49598.1 - 0.02 14.1 0.0 0.029 13.6 0.0 1.2 1 0 0 1 1 1 0 Histone methylation protein DOT1 Methyltransf_11 PF08241.7 CBZ49598.1 - 0.064 13.7 0.0 0.37 11.3 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain MTS PF05175.9 CBZ49598.1 - 0.078 12.3 0.0 0.14 11.4 0.0 1.4 2 0 0 2 2 2 0 Methyltransferase small domain CMAS PF02353.15 CBZ49598.1 - 0.1 11.6 0.0 0.15 11.1 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.1 CBZ49598.1 - 0.1 12.3 0.0 0.48 10.1 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_31 PF13847.1 CBZ49598.1 - 0.11 12.0 0.0 0.22 11.0 0.0 1.5 2 0 0 2 2 2 0 Methyltransferase domain FmrO PF07091.6 CBZ49598.1 - 0.11 11.4 0.0 0.19 10.7 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) ECH PF00378.15 CBZ49599.1 - 5.3e-08 32.2 0.0 1.4e-07 30.8 0.0 1.7 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family ECH_C PF13766.1 CBZ49599.1 - 1.8e-05 24.8 0.9 0.00097 19.2 0.1 2.3 2 0 0 2 2 2 2 2-enoyl-CoA Hydratase C-terminal region G6PD_C PF02781.11 CBZ49600.1 - 1.2e-70 237.6 0.0 7.5e-40 136.6 0.0 2.7 2 1 1 3 3 3 2 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.17 CBZ49600.1 - 3.8e-31 108.7 0.0 2.2e-24 86.7 0.0 2.4 1 1 1 2 2 2 2 Glucose-6-phosphate dehydrogenase, NAD binding domain Tropomyosin_1 PF12718.2 CBZ49601.1 - 0.00027 20.7 25.1 0.00027 20.7 17.4 5.5 2 2 3 5 5 5 2 Tropomyosin like GAS PF13851.1 CBZ49601.1 - 0.0016 17.6 6.3 0.0016 17.6 4.4 5.7 2 1 3 5 5 5 3 Growth-arrest specific micro-tubule binding Reo_sigmaC PF04582.7 CBZ49602.1 - 0.011 14.9 0.1 0.016 14.3 0.0 1.2 1 0 0 1 1 1 0 Reovirus sigma C capsid protein PDEase_I PF00233.14 CBZ49603.1 - 5.1e-52 176.9 0.2 6.8e-52 176.5 0.1 1.1 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase HD PF01966.17 CBZ49603.1 - 0.062 13.3 0.1 0.15 12.0 0.0 1.6 1 0 0 1 1 1 0 HD domain COX2_TM PF02790.10 CBZ49604.1 - 0.00017 21.4 0.0 0.00025 20.9 0.0 1.2 1 0 0 1 1 1 1 Cytochrome C oxidase subunit II, transmembrane domain WD40 PF00400.27 CBZ49606.1 - 2.4e-07 30.3 0.6 0.015 15.1 0.0 3.1 3 0 0 3 3 3 2 WD domain, G-beta repeat Pkinase PF00069.20 CBZ49607.1 - 9.9e-59 198.5 0.0 1.2e-58 198.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ49607.1 - 1.1e-38 132.7 0.0 1.4e-38 132.4 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBZ49607.1 - 3e-10 39.5 0.0 6.3e-10 38.4 0.0 1.5 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 CBZ49607.1 - 0.089 12.5 0.2 0.88 9.2 0.1 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family PRMT5 PF05185.11 CBZ49608.1 - 1.9e-18 66.6 0.0 2.8e-18 66.1 0.0 1.1 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase PrmA PF06325.8 CBZ49608.1 - 1e-07 31.4 0.0 1.5e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.2 CBZ49608.1 - 1.5e-07 31.9 0.0 4.7e-07 30.3 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 CBZ49608.1 - 3.1e-06 26.8 0.0 5.3e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 CBZ49608.1 - 5.7e-06 26.3 0.0 1.4e-05 25.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 CBZ49608.1 - 9.9e-05 21.7 0.0 0.00017 20.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Cons_hypoth95 PF03602.10 CBZ49608.1 - 0.0039 16.6 0.0 0.0064 15.9 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_11 PF08241.7 CBZ49608.1 - 0.0065 16.9 0.0 0.064 13.7 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 CBZ49608.1 - 0.014 15.0 0.0 0.038 13.7 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain FtsJ PF01728.14 CBZ49608.1 - 0.044 13.7 0.1 0.16 11.9 0.0 1.9 2 1 0 2 2 2 0 FtsJ-like methyltransferase Methyltransf_12 PF08242.7 CBZ49608.1 - 0.06 13.8 0.0 0.28 11.6 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_9 PF08003.6 CBZ49608.1 - 0.076 11.6 0.0 0.13 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) RrnaAD PF00398.15 CBZ49608.1 - 0.17 10.8 0.0 0.29 10.0 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Met_10 PF02475.11 CBZ49608.1 - 0.18 11.3 0.0 0.27 10.8 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein HECT PF00632.20 CBZ49609.1 - 6.3e-83 278.5 0.0 8.6e-83 278.1 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Macoilin PF09726.4 CBZ49609.1 - 0.14 10.3 39.9 0.24 9.6 27.6 1.3 1 0 0 1 1 1 0 Transmembrane protein DUF605 PF04652.11 CBZ49609.1 - 0.21 10.9 31.3 1.3 8.3 22.7 1.5 2 0 0 2 2 2 0 Vta1 like SOBP PF15279.1 CBZ49609.1 - 1.1 9.6 20.6 1.7 8.9 14.3 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein TFIIF_alpha PF05793.7 CBZ49609.1 - 8.4 4.6 33.1 13 4.0 22.9 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DER1 PF04511.10 CBZ49610.1 - 1.5e-38 132.3 7.2 1.8e-38 132.0 5.0 1.0 1 0 0 1 1 1 1 Der1-like family DUF2852 PF11014.3 CBZ49610.1 - 0.32 10.9 2.9 8.8 6.3 0.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2852) SSF PF00474.12 CBZ49611.1 - 2.1e-12 46.4 20.2 3.7e-12 45.5 14.0 1.3 1 0 0 1 1 1 1 Sodium:solute symporter family TPR_16 PF13432.1 CBZ49612.1 - 1.1e-14 54.5 17.8 0.00071 20.1 0.1 6.3 4 1 1 5 5 5 5 Tetratricopeptide repeat TPR_11 PF13414.1 CBZ49612.1 - 1.5e-13 50.1 10.6 5e-05 22.8 0.1 5.2 5 0 0 5 5 5 4 TPR repeat TPR_12 PF13424.1 CBZ49612.1 - 1.6e-09 37.5 12.7 0.00036 20.4 0.0 5.5 4 2 4 8 8 8 3 Tetratricopeptide repeat Apc3 PF12895.2 CBZ49612.1 - 4.4e-09 36.3 11.1 0.008 16.2 0.0 5.3 3 2 1 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.12 CBZ49612.1 - 1.5e-07 30.8 16.8 0.0018 18.0 0.3 7.9 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_8 PF13181.1 CBZ49612.1 - 7.6e-05 22.2 0.6 0.049 13.4 0.3 3.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.1 CBZ49612.1 - 0.00011 22.1 0.3 7.3 7.0 0.0 5.7 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_1 PF00515.23 CBZ49612.1 - 0.00074 19.0 6.9 0.34 10.6 0.6 5.9 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.1 CBZ49612.1 - 0.00076 19.7 11.7 0.38 11.1 0.1 5.4 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_20 PF14561.1 CBZ49612.1 - 0.0013 18.8 2.4 0.0098 15.9 0.2 3.5 4 1 1 5 5 4 1 Tetratricopeptide repeat TPR_14 PF13428.1 CBZ49612.1 - 0.0034 17.8 19.5 0.38 11.5 0.1 7.5 5 3 3 8 8 7 1 Tetratricopeptide repeat Histone PF00125.19 CBZ49613.1 - 3.4e-19 68.7 0.1 4.6e-19 68.3 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 CBZ49613.1 - 0.00028 20.8 0.2 0.00057 19.8 0.1 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.8 CBZ49613.1 - 0.00029 21.0 0.0 0.0005 20.2 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A Na_H_Exchanger PF00999.16 CBZ49614.1 - 3e-46 157.6 44.6 3.8e-46 157.3 30.9 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family CorA PF01544.13 CBZ49615.1 - 2.9e-06 26.5 0.9 6.3e-06 25.4 0.6 1.5 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein TPR_11 PF13414.1 CBZ49616.1 - 4.8e-15 54.9 10.1 0.00015 21.3 0.6 7.2 5 1 2 7 7 7 4 TPR repeat TPR_17 PF13431.1 CBZ49616.1 - 8.5e-12 44.3 8.0 0.12 12.6 0.0 8.1 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_2 PF07719.12 CBZ49616.1 - 5.3e-11 41.5 13.1 0.025 14.4 0.3 7.3 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_12 PF13424.1 CBZ49616.1 - 5.1e-10 39.1 12.5 0.00052 19.9 0.5 6.8 6 2 1 7 7 7 4 Tetratricopeptide repeat TPR_16 PF13432.1 CBZ49616.1 - 6.9e-10 39.3 25.3 0.0049 17.5 0.1 8.1 6 2 1 8 8 7 4 Tetratricopeptide repeat TPR_14 PF13428.1 CBZ49616.1 - 2e-08 34.1 30.2 0.0029 18.0 0.1 9.2 8 1 2 10 10 9 3 Tetratricopeptide repeat TPR_8 PF13181.1 CBZ49616.1 - 9.5e-08 31.3 0.1 2.1 8.3 0.0 6.4 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_19 PF14559.1 CBZ49616.1 - 1.8e-07 31.3 6.0 0.2 12.0 0.0 5.9 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.23 CBZ49616.1 - 1.6e-06 27.4 6.0 0.084 12.5 0.1 6.3 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_7 PF13176.1 CBZ49616.1 - 3.6e-06 26.3 10.9 0.1 12.4 0.1 6.3 8 0 0 8 8 8 2 Tetratricopeptide repeat Apc3 PF12895.2 CBZ49616.1 - 0.00036 20.6 2.4 0.46 10.6 0.0 4.5 4 0 0 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 Fis1_TPR_C PF14853.1 CBZ49616.1 - 0.021 14.6 1.2 3.7 7.4 0.0 3.6 4 0 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat TPR_6 PF13174.1 CBZ49616.1 - 0.45 11.0 6.8 8.5 7.0 0.1 4.8 5 0 0 5 5 3 0 Tetratricopeptide repeat DivIC PF04977.10 CBZ49617.1 - 3e-06 26.6 0.3 4.7e-06 25.9 0.2 1.3 1 0 0 1 1 1 1 Septum formation initiator TMF_DNA_bd PF12329.3 CBZ49617.1 - 1.1e-05 25.1 0.2 1.6e-05 24.6 0.2 1.3 1 0 0 1 1 1 1 TATA element modulatory factor 1 DNA binding bZIP_1 PF00170.16 CBZ49617.1 - 1.4e-05 24.9 0.4 2.2e-05 24.3 0.3 1.3 1 0 0 1 1 1 1 bZIP transcription factor HALZ PF02183.13 CBZ49617.1 - 3.5e-05 23.4 1.7 0.00031 20.3 0.4 1.8 1 1 0 1 1 1 1 Homeobox associated leucine zipper DUF904 PF06005.7 CBZ49617.1 - 0.00011 22.4 1.8 0.00011 22.4 1.2 1.6 2 0 0 2 2 1 1 Protein of unknown function (DUF904) ADIP PF11559.3 CBZ49617.1 - 0.00014 21.8 0.6 0.00022 21.1 0.4 1.3 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding bZIP_2 PF07716.10 CBZ49617.1 - 0.00085 19.0 0.9 0.0017 18.1 0.6 1.6 1 0 0 1 1 1 1 Basic region leucine zipper DivIVA PF05103.8 CBZ49617.1 - 0.0011 18.9 0.7 0.003 17.5 0.1 1.8 2 0 0 2 2 2 1 DivIVA protein KLRAQ PF10205.4 CBZ49617.1 - 0.0018 18.2 0.1 0.0032 17.4 0.1 1.4 1 0 0 1 1 1 1 Predicted coiled-coil domain-containing protein Atg14 PF10186.4 CBZ49617.1 - 0.0018 17.2 0.0 0.0018 17.2 0.0 1.1 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 Filament PF00038.16 CBZ49617.1 - 0.0025 17.3 0.6 0.0035 16.8 0.4 1.2 1 0 0 1 1 1 1 Intermediate filament protein DUF3373 PF11853.3 CBZ49617.1 - 0.0028 16.2 0.0 0.0032 16.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3373) DUF3450 PF11932.3 CBZ49617.1 - 0.0029 16.8 0.7 0.0038 16.5 0.2 1.4 2 0 0 2 2 1 1 Protein of unknown function (DUF3450) DUF1192 PF06698.6 CBZ49617.1 - 0.0045 16.7 1.9 0.064 13.0 0.3 2.3 1 1 1 2 2 2 1 Protein of unknown function (DUF1192) FlaC_arch PF05377.6 CBZ49617.1 - 0.0051 16.6 1.6 0.014 15.2 0.2 2.1 2 0 0 2 2 2 1 Flagella accessory protein C (FlaC) GAS PF13851.1 CBZ49617.1 - 0.0051 16.0 1.1 0.0065 15.6 0.2 1.5 2 0 0 2 2 2 1 Growth-arrest specific micro-tubule binding TBPIP PF07106.8 CBZ49617.1 - 0.0079 15.7 0.1 0.014 14.9 0.1 1.4 1 0 0 1 1 1 1 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF2968 PF11180.3 CBZ49617.1 - 0.0079 15.5 2.0 0.011 15.1 1.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2968) MAD PF05557.8 CBZ49617.1 - 0.0087 14.2 0.1 0.01 13.9 0.1 1.1 1 0 0 1 1 1 1 Mitotic checkpoint protein TPR_MLP1_2 PF07926.7 CBZ49617.1 - 0.0088 15.7 1.2 0.015 15.0 0.9 1.3 1 0 0 1 1 1 1 TPR/MLP1/MLP2-like protein WXG100 PF06013.7 CBZ49617.1 - 0.0098 15.8 0.4 0.017 15.1 0.3 1.4 1 0 0 1 1 1 1 Proteins of 100 residues with WXG WEMBL PF05701.6 CBZ49617.1 - 0.01 14.3 0.1 0.013 14.0 0.1 1.1 1 0 0 1 1 1 0 Weak chloroplast movement under blue light DUF2353 PF09789.4 CBZ49617.1 - 0.01 15.0 0.2 0.013 14.7 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) DUF4200 PF13863.1 CBZ49617.1 - 0.015 15.2 1.4 0.043 13.7 0.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) DUF4618 PF15397.1 CBZ49617.1 - 0.018 14.3 0.1 0.028 13.7 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) CENP-F_leu_zip PF10473.4 CBZ49617.1 - 0.02 14.7 0.5 0.037 13.8 0.4 1.4 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 GrpE PF01025.14 CBZ49617.1 - 0.02 14.4 0.9 0.25 10.8 0.1 2.0 2 0 0 2 2 2 0 GrpE Ax_dynein_light PF10211.4 CBZ49617.1 - 0.024 14.4 0.1 0.033 14.0 0.1 1.2 1 0 0 1 1 1 0 Axonemal dynein light chain FliD_C PF07195.7 CBZ49617.1 - 0.025 13.8 0.0 0.027 13.7 0.0 1.2 1 1 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus DUF603 PF04645.7 CBZ49617.1 - 0.028 14.3 0.0 0.038 13.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF603 Prefoldin_2 PF01920.15 CBZ49617.1 - 0.029 14.1 0.6 0.071 12.8 0.1 1.8 2 0 0 2 2 2 0 Prefoldin subunit DUF4140 PF13600.1 CBZ49617.1 - 0.03 14.7 0.2 0.045 14.2 0.1 1.3 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) Microtub_assoc PF07989.6 CBZ49617.1 - 0.032 14.0 0.4 0.065 13.0 0.3 1.5 1 0 0 1 1 1 0 Microtubule associated Seryl_tRNA_N PF02403.17 CBZ49617.1 - 0.034 14.1 0.4 0.057 13.4 0.3 1.3 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Pox_A_type_inc PF04508.7 CBZ49617.1 - 0.037 13.8 2.7 4.2 7.4 0.1 2.7 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat LPP PF04728.8 CBZ49617.1 - 0.038 13.7 0.5 0.28 11.0 0.4 2.0 1 1 1 2 2 2 0 Lipoprotein leucine-zipper Phasin PF05597.6 CBZ49617.1 - 0.038 13.7 1.1 2.7 7.7 0.0 2.2 1 1 1 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Spc24 PF08286.6 CBZ49617.1 - 0.042 13.5 0.3 0.067 12.8 0.2 1.3 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 Sipho_Gp157 PF05565.6 CBZ49617.1 - 0.05 13.1 0.1 0.086 12.4 0.0 1.5 2 0 0 2 2 1 0 Siphovirus Gp157 MbeD_MobD PF04899.7 CBZ49617.1 - 0.064 13.1 0.4 0.12 12.3 0.2 1.5 1 0 0 1 1 1 0 MbeD/MobD like AKNA PF12443.3 CBZ49617.1 - 0.064 13.2 0.6 0.11 12.4 0.4 1.4 1 0 0 1 1 1 0 AT-hook-containing transcription factor Uds1 PF15456.1 CBZ49617.1 - 0.066 13.2 0.6 0.1 12.6 0.4 1.3 1 0 0 1 1 1 0 Up-regulated During Septation Cortex-I_coil PF09304.5 CBZ49617.1 - 0.066 13.2 1.5 0.11 12.4 1.0 1.3 1 0 0 1 1 1 0 Cortexillin I, coiled coil DUF1843 PF08898.5 CBZ49617.1 - 0.067 13.2 0.9 0.067 13.2 0.6 1.6 2 0 0 2 2 1 0 Domain of unknown function (DUF1843) DUF972 PF06156.8 CBZ49617.1 - 0.067 13.5 0.3 0.15 12.4 0.1 1.6 2 0 0 2 2 1 0 Protein of unknown function (DUF972) Cluap1 PF10234.4 CBZ49617.1 - 0.068 12.3 1.2 0.086 12.0 0.1 1.6 2 0 0 2 2 2 0 Clusterin-associated protein-1 TSC22 PF01166.13 CBZ49617.1 - 0.068 13.1 0.6 0.068 13.1 0.4 1.6 2 0 0 2 2 1 0 TSC-22/dip/bun family Macoilin PF09726.4 CBZ49617.1 - 0.074 11.3 0.3 0.09 11.0 0.2 1.1 1 0 0 1 1 1 0 Transmembrane protein APG6 PF04111.7 CBZ49617.1 - 0.074 12.0 0.1 0.087 11.8 0.1 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 CCDC92 PF14916.1 CBZ49617.1 - 0.092 12.3 3.8 3.2 7.4 0.6 2.7 2 1 1 3 3 2 0 Coiled-coil domain of unknown function PEP-utilisers_N PF05524.8 CBZ49617.1 - 0.11 12.2 0.1 0.16 11.8 0.1 1.2 1 0 0 1 1 1 0 PEP-utilising enzyme, N-terminal IncA PF04156.9 CBZ49617.1 - 0.11 12.0 2.7 0.12 11.9 1.9 1.3 1 1 0 1 1 1 0 IncA protein Prefoldin PF02996.12 CBZ49617.1 - 0.15 11.7 1.1 0.29 10.8 0.7 1.5 1 0 0 1 1 1 0 Prefoldin subunit NYD-SP28_assoc PF14775.1 CBZ49617.1 - 0.15 11.7 0.7 0.58 9.8 0.2 2.2 1 1 1 2 2 2 0 Sperm tail C-terminal domain Kinesin-relat_1 PF12711.2 CBZ49617.1 - 0.19 12.1 0.6 0.19 12.1 0.4 1.8 2 0 0 2 2 1 0 Kinesin motor HalX PF08663.5 CBZ49617.1 - 0.24 11.4 3.1 1.5 8.8 0.4 2.2 1 1 1 2 2 2 0 HalX domain Wbp11 PF09429.5 CBZ49617.1 - 0.29 11.1 3.0 0.24 11.3 0.8 1.8 2 0 0 2 2 1 0 WW domain binding protein 11 FlxA PF14282.1 CBZ49617.1 - 0.33 10.9 3.5 0.77 9.7 2.5 1.7 1 1 0 1 1 1 0 FlxA-like protein Cep57_CLD_2 PF14197.1 CBZ49617.1 - 0.37 10.7 5.3 0.64 9.9 2.0 2.3 2 1 0 2 2 1 0 Centrosome localisation domain of PPC89 IFP_35_N PF07334.8 CBZ49617.1 - 4.2 7.4 5.9 0.83 9.6 1.7 1.6 2 0 0 2 2 1 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus Dynamin_N PF00350.18 CBZ49618.1 - 0.034 13.9 0.1 0.034 13.9 0.0 3.0 4 0 0 4 4 4 0 Dynamin family Miro PF08477.8 CBZ49618.1 - 0.084 13.3 0.0 0.19 12.2 0.0 1.6 1 0 0 1 1 1 0 Miro-like protein AAA_29 PF13555.1 CBZ49618.1 - 0.15 11.5 0.0 0.4 10.2 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain MMR_HSR1 PF01926.18 CBZ49618.1 - 0.17 11.8 0.0 0.37 10.7 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase DUF599 PF04654.7 CBZ49618.1 - 0.52 9.4 0.2 1 8.4 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF599 MutS_V PF00488.16 CBZ49618.1 - 0.65 9.3 0.0 1.1 8.5 0.0 1.2 1 0 0 1 1 1 0 MutS domain V Suf PF05843.9 CBZ49619.1 - 2.2e-10 40.7 17.4 3.2e-05 23.8 0.1 5.3 4 2 2 6 6 6 4 Suppressor of forked protein (Suf) TPR_12 PF13424.1 CBZ49619.1 - 1.1e-09 38.1 15.8 0.042 13.8 0.0 8.9 9 1 1 10 10 10 2 Tetratricopeptide repeat TPR_16 PF13432.1 CBZ49619.1 - 2.1e-06 28.2 27.8 0.0066 17.1 0.8 7.5 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_14 PF13428.1 CBZ49619.1 - 3.1e-05 24.2 27.5 0.036 14.7 0.1 10.6 10 3 2 12 12 11 1 Tetratricopeptide repeat TPR_15 PF13429.1 CBZ49619.1 - 7.9e-05 21.8 20.4 0.098 11.7 0.2 5.9 5 1 2 7 7 7 4 Tetratricopeptide repeat TPR_2 PF07719.12 CBZ49619.1 - 0.00032 20.4 13.4 0.013 15.3 0.1 7.1 8 0 0 8 8 8 1 Tetratricopeptide repeat HSP90 PF00183.13 CBZ49619.1 - 0.0008 17.9 2.1 0.0008 17.9 1.5 2.1 2 0 0 2 2 2 1 Hsp90 protein TPR_8 PF13181.1 CBZ49619.1 - 0.0045 16.6 4.7 4.5 7.2 0.0 5.1 5 0 0 5 5 4 2 Tetratricopeptide repeat PPR PF01535.15 CBZ49619.1 - 0.012 15.5 0.0 0.22 11.5 0.0 3.2 3 0 0 3 3 3 0 PPR repeat TPR_7 PF13176.1 CBZ49619.1 - 0.017 14.8 11.1 0.036 13.8 0.0 6.3 8 0 0 8 8 7 0 Tetratricopeptide repeat TPR_1 PF00515.23 CBZ49619.1 - 0.028 14.0 2.1 0.46 10.1 0.0 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat YrhK PF14145.1 CBZ49620.1 - 0.83 9.3 5.7 9.4 5.9 0.1 2.8 3 0 0 3 3 3 0 YrhK-like protein Abhydrolase_6 PF12697.2 CBZ49621.1 - 1.6e-15 57.6 0.2 1.7e-14 54.2 0.0 2.3 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CBZ49621.1 - 5.1e-14 52.2 0.0 3.7e-13 49.4 0.0 2.2 1 1 1 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 CBZ49621.1 - 1.7e-10 40.5 0.2 1.5e-07 31.1 0.0 2.6 2 0 0 2 2 2 2 Putative lysophospholipase Abhydrolase_3 PF07859.8 CBZ49621.1 - 7.1e-05 22.4 0.0 0.00016 21.3 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_1 PF00561.15 CBZ49621.1 - 0.00073 19.1 0.3 0.002 17.7 0.2 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF2305 PF10230.4 CBZ49621.1 - 0.0024 17.3 0.0 0.004 16.5 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) DUF900 PF05990.7 CBZ49621.1 - 0.016 14.5 0.0 0.029 13.6 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) UDG PF03167.14 CBZ49622.1 - 0.011 15.2 0.0 0.025 14.0 0.0 1.6 1 1 0 1 1 1 0 Uracil DNA glycosylase superfamily Pkinase PF00069.20 CBZ49623.1 - 1.7e-58 197.8 0.0 1.9e-58 197.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ49623.1 - 6.8e-34 117.1 0.0 8.1e-34 116.8 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CBZ49623.1 - 0.00026 20.7 0.1 0.23 11.1 0.1 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.1 CBZ49623.1 - 0.00055 18.9 0.0 0.0012 17.9 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 CBZ49623.1 - 0.0048 15.9 0.0 0.0091 15.0 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 CBZ49623.1 - 0.14 11.5 0.0 0.72 9.1 0.0 1.8 1 1 1 2 2 2 0 RIO1 family EF_TS PF00889.14 CBZ49624.1 - 5.4e-37 127.2 0.2 5.6e-22 78.1 0.0 3.1 3 0 0 3 3 3 3 Elongation factor TS UBA PF00627.26 CBZ49624.1 - 0.00016 21.4 0.0 0.00029 20.5 0.0 1.5 1 0 0 1 1 1 1 UBA/TS-N domain UBA_4 PF14555.1 CBZ49624.1 - 0.00056 19.3 0.1 0.0013 18.2 0.0 1.6 1 0 0 1 1 1 1 UBA-like domain T2SF PF00482.18 CBZ49624.1 - 0.18 11.7 0.9 0.47 10.3 0.1 2.1 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein F DUF21 PF01595.15 CBZ49626.1 - 3.5e-26 91.6 2.9 6.1e-26 90.8 2.0 1.3 1 0 0 1 1 1 1 Domain of unknown function DUF21 CBS PF00571.23 CBZ49626.1 - 0.00011 21.9 0.5 0.016 14.9 0.0 3.2 3 1 0 3 3 3 2 CBS domain NAD_Gly3P_dh_C PF07479.9 CBZ49627.1 - 8.9e-43 145.5 0.0 2.4e-42 144.1 0.0 1.7 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus NAD_Gly3P_dh_N PF01210.18 CBZ49627.1 - 6e-38 130.0 0.0 1.1e-37 129.2 0.0 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus DUF3661 PF12400.3 CBZ49630.1 - 2.1e-35 121.5 6.4 3.1e-35 121.0 4.4 1.2 1 0 0 1 1 1 1 Vaculolar membrane protein DUF4381 PF14316.1 CBZ49630.1 - 0.32 11.0 0.1 0.32 11.0 0.0 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4381) DUF3099 PF11298.3 CBZ49630.1 - 1.1 9.0 5.9 3.2 7.5 4.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3099) RNase_Zc3h12a PF11977.3 CBZ49631.1 - 0.0001 22.1 0.0 0.024 14.4 0.0 2.3 2 0 0 2 2 2 2 Zc3h12a-like Ribonuclease NYN domain SpoIIE PF07228.7 CBZ49633.1 - 3e-09 36.8 0.0 4e-05 23.3 0.0 2.4 2 0 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) PP2C PF00481.16 CBZ49633.1 - 0.002 17.5 0.0 0.19 11.1 0.0 2.3 2 0 0 2 2 2 2 Protein phosphatase 2C Pkinase PF00069.20 CBZ49634.1 - 2.3e-64 217.0 0.0 2.3e-64 217.0 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ49634.1 - 4.1e-26 91.6 0.0 7.2e-26 90.8 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBZ49634.1 - 1.7e-05 23.9 0.0 4.4e-05 22.5 0.0 1.6 2 0 0 2 2 2 1 Kinase-like GBP PF02263.14 CBZ49635.1 - 6.1e-16 58.2 0.0 1.2e-10 40.8 0.0 3.1 2 1 0 2 2 2 2 Guanylate-binding protein, N-terminal domain SICA_alpha PF12887.2 CBZ49635.1 - 0.082 12.6 13.7 0.055 13.2 2.5 3.7 4 0 0 4 4 4 0 SICA extracellular alpha domain RRM_1 PF00076.17 CBZ49636.1 - 8e-18 63.8 0.1 1.3e-17 63.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBZ49636.1 - 7.5e-13 48.2 0.0 1.2e-12 47.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBZ49636.1 - 6.4e-09 35.5 0.0 1e-08 34.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CS PF04969.11 CBZ49637.1 - 1.4e-08 35.1 0.0 3e-08 34.0 0.0 1.5 1 0 0 1 1 1 1 CS domain DUF605 PF04652.11 CBZ49637.1 - 8.9 5.6 34.3 0.27 10.5 11.8 2.4 2 0 0 2 2 2 0 Vta1 like PfkB PF00294.19 CBZ49638.1 - 8.9e-46 156.3 2.1 3.2e-28 98.7 0.5 2.7 2 1 0 2 2 2 2 pfkB family carbohydrate kinase Penicil_amidase PF01804.13 CBZ49639.1 - 0.13 11.2 5.5 0.021 13.8 0.3 2.1 2 0 0 2 2 2 0 Penicillin amidase HEAT_2 PF13646.1 CBZ49639.1 - 1.2 9.5 47.5 0.077 13.2 0.6 8.3 5 3 2 7 7 7 0 HEAT repeats EF-hand_1 PF00036.27 CBZ49640.1 - 4.1e-18 63.2 0.1 9.2e-05 21.4 0.0 3.9 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.1 CBZ49640.1 - 3.3e-16 59.1 0.0 1.5e-10 41.0 0.0 2.1 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 CBZ49640.1 - 2.5e-13 48.6 0.1 0.00022 20.8 0.0 3.7 3 1 2 5 5 5 3 EF-hand domain EF-hand_8 PF13833.1 CBZ49640.1 - 8.8e-12 44.4 0.4 6.5e-07 28.8 0.0 3.3 3 1 1 4 4 4 2 EF-hand domain pair EF-hand_5 PF13202.1 CBZ49640.1 - 9.9e-11 40.4 0.0 0.00049 19.3 0.0 3.3 3 0 0 3 3 3 2 EF hand EF-hand_9 PF14658.1 CBZ49640.1 - 7.6e-05 22.5 0.1 0.00064 19.5 0.0 2.2 2 1 1 3 3 3 1 EF-hand domain SPARC_Ca_bdg PF10591.4 CBZ49640.1 - 0.00037 20.5 0.0 0.0019 18.2 0.0 1.9 2 0 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 CBZ49640.1 - 0.0064 16.2 0.0 2.9 7.6 0.0 2.2 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_10 PF14788.1 CBZ49640.1 - 0.013 15.1 0.1 2.9 7.6 0.0 2.8 3 0 0 3 3 3 0 EF hand FANCI_HD2 PF14680.1 CBZ49640.1 - 0.11 11.6 0.1 0.2 10.7 0.1 1.6 1 1 0 1 1 1 0 FANCI helical domain 2 TerB PF05099.8 CBZ49640.1 - 0.13 12.0 0.1 1.4 8.6 0.0 2.3 2 1 1 3 3 3 0 Tellurite resistance protein TerB Ubiquitin_2 PF14560.1 CBZ49641.1 - 2.6e-10 40.4 0.0 4.3e-10 39.6 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-like domain CAP_GLY PF01302.20 CBZ49641.1 - 7.1e-10 38.4 0.1 3.1e-09 36.3 0.0 2.0 1 1 0 1 1 1 1 CAP-Gly domain Oxysterol_BP PF01237.13 CBZ49644.1 - 2.1e-101 338.9 0.1 1.4e-66 224.4 0.0 2.2 2 0 0 2 2 2 2 Oxysterol-binding protein DUF1826 PF08856.6 CBZ49644.1 - 0.051 13.3 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1826) AMA-1 PF02430.10 CBZ49645.1 - 1.2e-18 67.2 8.9 1.5e-14 53.8 2.4 3.4 2 1 1 3 3 3 2 Apical membrane antigen 1 EGF_2 PF07974.8 CBZ49645.1 - 9.6e-15 54.4 280.2 0.0003 20.8 8.9 14.9 13 1 1 14 14 14 10 EGF-like domain hEGF PF12661.2 CBZ49645.1 - 0.0074 16.3 10.2 0.016 15.2 1.7 14.2 15 0 0 15 15 15 7 Human growth factor-like EGF EGF PF00008.22 CBZ49645.1 - 0.0079 16.1 11.9 0.0079 16.1 8.3 15.0 14 1 1 15 15 15 6 EGF-like domain Mitofilin PF09731.4 CBZ49646.1 - 0.66 8.5 8.5 0.78 8.3 5.9 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein PAT1 PF09770.4 CBZ49646.1 - 3.5 5.7 16.0 4.3 5.4 11.1 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DEAD PF00270.24 CBZ49647.1 - 4.8e-17 61.9 0.0 1.2e-16 60.6 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 CBZ49647.1 - 4.8e-05 23.2 0.0 0.0002 21.2 0.0 2.1 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 CBZ49647.1 - 0.0012 18.6 0.0 0.0034 17.1 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AdoMet_Synthase PF01941.14 CBZ49647.1 - 0.34 9.3 0.0 0.57 8.6 0.0 1.2 1 0 0 1 1 1 0 S-adenosylmethionine synthetase (AdoMet synthetase) UCH PF00443.24 CBZ49648.1 - 1.9e-38 132.1 0.0 2.7e-38 131.6 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 CBZ49648.1 - 1e-10 41.5 8.9 2.1e-10 40.5 6.1 1.5 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.1 CBZ49648.1 - 1.9e-08 34.1 0.0 4e-08 33.0 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUF2388 PF09498.5 CBZ49648.1 - 0.075 12.6 0.1 0.14 11.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2388) DUF3678 PF12435.3 CBZ49649.1 - 0.082 12.4 0.8 0.082 12.4 0.6 4.4 3 1 0 3 3 3 0 Protein of unknown function (DUF3678) Aminotran_5 PF00266.14 CBZ49650.1 - 6.7e-26 90.8 0.0 8.9e-18 64.1 0.0 3.4 2 1 0 2 2 2 2 Aminotransferase class-V ATP_bind_3 PF01171.15 CBZ49650.1 - 5.4e-17 61.8 0.0 9.7e-17 61.0 0.0 1.4 1 0 0 1 1 1 1 PP-loop family Fez1 PF06818.10 CBZ49650.1 - 2.3 8.1 7.3 0.054 13.5 0.4 1.6 2 0 0 2 2 2 0 Fez1 CLAG PF03805.8 CBZ49652.1 - 3.8e-09 34.5 3.8 3.8e-09 34.5 2.6 2.1 2 1 0 2 2 2 1 Cytoadherence-linked asexual protein IBV_3A PF03617.8 CBZ49652.1 - 0.0013 18.4 1.2 0.0031 17.2 0.8 1.6 1 0 0 1 1 1 1 IBV 3A protein ACT_6 PF13740.1 CBZ49652.1 - 0.08 12.6 0.1 0.65 9.7 0.0 2.4 2 0 0 2 2 2 0 ACT domain PDCD2_C PF04194.8 CBZ49654.1 - 2.9e-17 62.7 8.9 6.7e-17 61.5 0.2 3.4 2 1 2 4 4 4 2 Programmed cell death protein 2, C-terminal putative domain Rad50_zn_hook PF04423.9 CBZ49654.1 - 0.77 9.2 15.1 1.9 8.0 1.1 4.0 4 0 0 4 4 4 0 Rad50 zinc hook motif SDA1 PF05285.7 CBZ49655.1 - 1.7e-36 126.1 88.4 5.9e-36 124.3 54.0 3.2 2 1 0 2 2 2 2 SDA1 NUC130_3NT PF08158.7 CBZ49655.1 - 0.0029 17.8 3.7 0.063 13.5 1.2 2.7 2 0 0 2 2 2 1 NUC130/3NT domain Nol1_Nop2_Fmu PF01189.12 CBZ49656.1 - 9.5e-33 113.7 0.0 9.5e-19 67.8 0.0 4.3 3 1 1 4 4 4 4 NOL1/NOP2/sun family Dynein_heavy PF03028.10 CBZ49657.1 - 2.8e-140 468.6 0.0 9e-139 463.6 0.0 2.7 2 1 0 2 2 1 1 Dynein heavy chain and region D6 of dynein motor DHC_N1 PF08385.7 CBZ49657.1 - 5.1e-136 454.4 0.3 5.1e-136 454.4 0.2 4.9 6 2 1 7 7 7 1 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.8 CBZ49657.1 - 3.5e-127 424.2 1.0 3.5e-127 424.2 0.7 3.3 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 2 AAA_6 PF12774.2 CBZ49657.1 - 1.2e-83 280.2 0.0 3.1e-83 278.8 0.0 1.7 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region D1 AAA_9 PF12781.2 CBZ49657.1 - 1.7e-42 144.8 0.1 3.5e-42 143.7 0.0 1.5 1 0 0 1 1 1 1 ATP-binding dynein motor region D5 AAA_8 PF12780.2 CBZ49657.1 - 4.3e-34 117.7 0.0 3.2e-33 114.8 0.0 2.2 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 MT PF12777.2 CBZ49657.1 - 3.8e-32 111.3 12.3 6.6e-32 110.5 6.9 2.3 2 0 0 2 2 2 1 Microtubule-binding stalk of dynein motor AAA_5 PF07728.9 CBZ49657.1 - 6.7e-32 110.1 0.0 8.1e-12 45.0 0.0 6.9 5 1 0 5 5 5 4 AAA domain (dynein-related subfamily) AAA PF00004.24 CBZ49657.1 - 1.9e-15 57.2 0.1 0.00061 19.9 0.0 5.4 4 0 0 4 4 4 3 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.2 CBZ49657.1 - 1.8e-13 50.1 0.0 3.7e-12 45.9 0.0 2.7 3 0 0 3 3 3 1 P-loop containing dynein motor region D3 AAA_22 PF13401.1 CBZ49657.1 - 1.3e-11 44.7 4.3 0.00087 19.4 0.0 7.2 7 1 0 7 7 5 2 AAA domain AAA_17 PF13207.1 CBZ49657.1 - 2.1e-07 31.7 0.0 3.9 8.3 0.0 5.6 4 0 0 4 4 4 2 AAA domain AAA_18 PF13238.1 CBZ49657.1 - 1.4e-06 28.5 0.0 1.1 9.5 0.0 5.1 4 0 0 4 4 4 1 AAA domain AAA_33 PF13671.1 CBZ49657.1 - 7.7e-06 25.8 1.2 0.48 10.3 0.0 5.3 5 0 0 5 5 4 1 AAA domain AAA_19 PF13245.1 CBZ49657.1 - 1e-05 25.1 3.0 0.5 10.1 0.0 5.1 5 0 0 5 5 5 1 Part of AAA domain AAA_14 PF13173.1 CBZ49657.1 - 2.4e-05 24.2 0.0 0.55 10.1 0.0 4.8 5 0 0 5 5 5 2 AAA domain AAA_25 PF13481.1 CBZ49657.1 - 6.3e-05 22.4 0.8 0.022 14.1 0.0 4.1 4 0 0 4 4 4 1 AAA domain ResIII PF04851.10 CBZ49657.1 - 0.0026 17.6 0.2 0.91 9.3 0.0 4.2 4 0 0 4 4 3 1 Type III restriction enzyme, res subunit AAA_29 PF13555.1 CBZ49657.1 - 0.0038 16.7 0.0 12 5.5 0.0 3.8 3 0 0 3 3 3 0 P-loop containing region of AAA domain RNA_helicase PF00910.17 CBZ49657.1 - 0.018 15.1 0.1 1.4e+02 2.6 0.0 4.7 5 0 0 5 5 4 0 RNA helicase Mg_chelatase PF01078.16 CBZ49657.1 - 0.023 13.8 5.6 5.6 6.0 0.0 4.4 4 1 1 5 5 5 0 Magnesium chelatase, subunit ChlI MR_MLE_C PF13378.1 CBZ49657.1 - 0.027 14.4 0.0 0.4 10.6 0.0 2.6 2 0 0 2 2 2 0 Enolase C-terminal domain-like PLRV_ORF5 PF01690.12 CBZ49657.1 - 8.5 5.3 2.1 16 4.4 1.5 1.3 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Pkinase PF00069.20 CBZ49658.1 - 1.2e-12 47.5 0.0 1.7e-09 37.2 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Kinase-like PF14531.1 CBZ49658.1 - 7.8e-09 34.8 0.0 1.4e-08 34.0 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Pkinase_Tyr PF07714.12 CBZ49658.1 - 0.056 12.4 0.0 0.08 11.9 0.0 1.4 1 0 0 1 1 1 0 Protein tyrosine kinase Rhodanese PF00581.15 CBZ49659.1 - 3.4e-13 49.9 0.0 1e-12 48.3 0.0 1.8 1 0 0 1 1 1 1 Rhodanese-like domain Cluap1 PF10234.4 CBZ49659.1 - 0.24 10.5 15.0 0.49 9.5 10.4 1.5 1 0 0 1 1 1 0 Clusterin-associated protein-1 V_ATPase_I PF01496.14 CBZ49659.1 - 5.5 4.7 11.5 7.9 4.1 7.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TMPIT PF07851.8 CBZ49659.1 - 6.3 5.7 13.6 12 4.8 9.4 1.4 1 0 0 1 1 1 0 TMPIT-like protein EB1 PF03271.12 CBZ49661.1 - 0.00015 21.7 1.1 0.0003 20.7 0.8 1.5 1 0 0 1 1 1 1 EB1-like C-terminal motif GBP PF02263.14 CBZ49662.1 - 0.46 9.4 3.0 0.85 8.6 2.1 1.3 1 0 0 1 1 1 0 Guanylate-binding protein, N-terminal domain SET PF00856.23 CBZ49663.1 - 6.2e-05 23.3 0.9 0.0008 19.7 0.0 3.4 3 1 0 3 3 3 1 SET domain LMBR1 PF04791.11 CBZ49663.1 - 2.7 6.4 0.7 5.1 5.5 0.0 1.7 2 0 0 2 2 2 0 LMBR1-like membrane protein eIF-3c_N PF05470.7 CBZ49664.1 - 5.1e-122 407.9 28.4 9.7e-121 403.7 19.7 2.3 1 1 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.22 CBZ49664.1 - 1e-14 54.6 0.7 2.3e-13 50.3 0.0 2.9 2 0 0 2 2 2 1 PCI domain Apc3 PF12895.2 CBZ49664.1 - 0.025 14.7 0.5 0.14 12.3 0.3 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.12 CBZ49664.1 - 0.083 12.8 0.6 0.61 10.1 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF830 PF05708.7 CBZ49666.1 - 2.6e-15 56.7 0.0 3.9e-15 56.1 0.0 1.2 1 0 0 1 1 1 1 Orthopoxvirus protein of unknown function (DUF830) PH PF00169.24 CBZ49666.1 - 7.7e-09 35.7 0.0 1.3e-08 34.9 0.0 1.5 1 1 0 1 1 1 1 PH domain PH_11 PF15413.1 CBZ49666.1 - 3.3e-07 30.5 0.2 7e-07 29.4 0.1 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain PH_3 PF14593.1 CBZ49666.1 - 0.0027 17.5 0.0 0.031 14.1 0.0 2.2 2 0 0 2 2 2 1 PH domain PH_8 PF15409.1 CBZ49666.1 - 0.003 17.5 0.0 0.0064 16.5 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain DUF1703 PF08011.6 CBZ49666.1 - 0.15 11.7 0.0 0.35 10.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1703) Ribonuc_red_lgC PF02867.10 CBZ49667.1 - 1.3e-210 700.5 0.0 1.7e-210 700.1 0.0 1.2 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.16 CBZ49667.1 - 2.7e-23 81.5 0.0 6e-23 80.4 0.0 1.6 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.11 CBZ49667.1 - 5.3e-11 42.8 0.0 1.2e-10 41.6 0.0 1.7 1 0 0 1 1 1 1 ATP cone domain DUF3275 PF11679.3 CBZ49667.1 - 0.16 11.5 0.0 0.49 9.9 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3275) RRM_1 PF00076.17 CBZ49669.1 - 1.6e-17 62.8 0.4 1.1e-15 57.0 0.0 3.1 4 0 0 4 4 4 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBZ49669.1 - 1.6e-13 50.3 0.0 3.7e-13 49.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) eIF3g PF12353.3 CBZ49669.1 - 2.9e-12 46.6 1.1 2.9e-12 46.6 0.7 4.3 5 0 0 5 5 5 1 Eukaryotic translation initiation factor 3 subunit G RRM_5 PF13893.1 CBZ49669.1 - 1.6e-07 31.0 0.1 3e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Rhomboid PF01694.17 CBZ49670.1 - 3.7e-21 75.6 15.7 9e-21 74.4 10.9 1.7 1 0 0 1 1 1 1 Rhomboid family MBOAT_2 PF13813.1 CBZ49670.1 - 0.012 15.6 0.2 0.042 13.9 0.0 2.0 2 0 0 2 2 2 0 Membrane bound O-acyl transferase family Glug PF07581.7 CBZ49670.1 - 0.73 10.1 4.2 17 5.8 0.2 2.6 2 0 0 2 2 2 0 The GLUG motif MobB PF03205.9 CBZ49671.1 - 0.00029 20.5 0.0 0.00061 19.5 0.0 1.6 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_17 PF13207.1 CBZ49671.1 - 0.0062 17.3 0.0 0.03 15.1 0.0 2.1 1 1 0 1 1 1 1 AAA domain Clp1 PF06807.9 CBZ49671.1 - 0.0084 15.8 0.0 0.014 15.1 0.0 1.5 1 1 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 RRM_1 PF00076.17 CBZ49672.1 - 2.2e-22 78.4 0.0 2.5e-11 43.0 0.1 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBZ49672.1 - 4.1e-15 55.5 0.0 1.4e-07 31.3 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBZ49672.1 - 1.6e-05 24.6 0.0 0.00081 19.1 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Lip_prot_lig_C PF10437.4 CBZ49672.1 - 0.15 11.7 0.1 20 4.9 0.0 2.2 2 0 0 2 2 2 0 Bacterial lipoate protein ligase C-terminus zf-RING_2 PF13639.1 CBZ49673.1 - 3e-08 33.3 5.6 1.4e-07 31.2 2.0 2.5 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.1 CBZ49673.1 - 2.8e-07 30.1 2.2 2.8e-07 30.1 1.5 2.0 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 CBZ49673.1 - 1.7e-06 27.5 3.4 1.7e-06 27.5 2.4 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CBZ49673.1 - 2.1e-06 27.6 3.4 2.1e-06 27.6 2.3 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CBZ49673.1 - 0.00023 20.7 2.7 0.00023 20.7 1.9 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 CBZ49673.1 - 0.00045 20.2 1.2 0.0022 18.0 0.4 2.2 2 0 0 2 2 2 1 RING-H2 zinc finger zf-RING_UBOX PF13445.1 CBZ49673.1 - 0.0046 16.6 3.7 0.0059 16.2 1.4 2.0 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_4 PF14570.1 CBZ49673.1 - 0.0049 16.4 2.0 0.011 15.2 1.4 1.6 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-RING_6 PF14835.1 CBZ49673.1 - 0.049 13.4 0.6 0.11 12.3 0.4 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-P11 PF03854.9 CBZ49673.1 - 0.15 11.5 1.6 0.36 10.3 1.1 1.5 1 0 0 1 1 1 0 P-11 zinc finger zf-C3HC4_4 PF15227.1 CBZ49673.1 - 0.59 10.0 6.1 0.9 9.4 3.2 2.1 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING Sec16_C PF12931.2 CBZ49674.1 - 2.9e-13 50.2 0.0 1.1e-12 48.3 0.0 1.8 1 1 0 1 1 1 1 Sec23-binding domain of Sec16 Arm PF00514.18 CBZ49676.1 - 1.1e-11 44.0 5.4 0.0021 17.7 0.0 5.7 5 0 0 5 5 5 3 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 CBZ49676.1 - 9.3e-09 35.4 2.9 1.5e-05 25.1 0.0 3.8 2 1 1 3 3 3 2 HEAT repeats V-ATPase_H_C PF11698.3 CBZ49676.1 - 0.00039 20.3 0.0 0.0026 17.6 0.0 2.0 2 0 0 2 2 2 1 V-ATPase subunit H HEAT_EZ PF13513.1 CBZ49676.1 - 0.0068 16.8 0.1 0.13 12.8 0.0 3.1 2 0 0 2 2 2 1 HEAT-like repeat HEAT PF02985.17 CBZ49676.1 - 0.013 15.5 6.4 22 5.4 0.0 5.1 5 0 0 5 5 5 0 HEAT repeat DUF1631 PF07793.6 CBZ49676.1 - 3.1 5.8 6.0 4.5 5.2 4.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) THOC7 PF05615.8 CBZ49677.1 - 6.7e-08 32.8 3.0 6.7e-08 32.8 2.1 1.9 1 1 1 2 2 2 1 Tho complex subunit 7 Tweety PF04906.8 CBZ49678.1 - 0.049 12.0 0.0 0.072 11.5 0.0 1.3 1 0 0 1 1 1 0 Tweety Spore_coat_CotO PF14153.1 CBZ49678.1 - 0.32 10.3 9.8 0.073 12.4 4.6 1.5 2 0 0 2 2 2 0 Spore coat protein CotO Macoilin PF09726.4 CBZ49678.1 - 0.44 8.7 5.5 0.53 8.5 3.8 1.1 1 0 0 1 1 1 0 Transmembrane protein Peptidase_S64 PF08192.6 CBZ49678.1 - 0.77 8.0 4.8 1 7.6 3.3 1.1 1 0 0 1 1 1 0 Peptidase family S64 GTP_EFTU PF00009.22 CBZ49679.1 - 3.2e-56 189.7 0.0 5.2e-56 189.0 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 CBZ49679.1 - 6.8e-36 122.4 0.3 2.8e-35 120.4 0.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 CBZ49679.1 - 4.3e-15 55.5 0.3 1.4e-14 53.9 0.2 2.0 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 CBZ49679.1 - 0.00018 21.4 0.0 0.00057 19.8 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.1 CBZ49679.1 - 0.00079 19.0 0.2 0.0026 17.3 0.1 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 4 FlpD PF02662.11 CBZ49679.1 - 0.022 14.4 0.1 0.068 12.8 0.0 1.8 2 0 0 2 2 2 0 Methyl-viologen-reducing hydrogenase, delta subunit RRM_6 PF14259.1 CBZ49680.1 - 7.8e-10 38.5 0.0 1.4e-09 37.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CBZ49680.1 - 6.3e-08 32.1 0.0 1.2e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ketoacyl-synt PF00109.21 CBZ49681.1 - 0 1116.2 6.1 1.4e-87 293.3 0.2 4.8 4 0 0 4 4 4 4 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 CBZ49681.1 - 1.3e-251 826.5 0.6 3.3e-65 219.1 0.0 4.9 4 0 0 4 4 4 4 KR domain adh_short PF00106.20 CBZ49681.1 - 4.8e-202 664.2 10.8 1.9e-51 174.3 0.0 5.8 6 0 0 6 6 5 4 short chain dehydrogenase PS-DH PF14765.1 CBZ49681.1 - 9.7e-188 622.4 16.4 7.1e-53 179.6 0.2 5.6 5 0 0 5 5 5 5 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.17 CBZ49681.1 - 7.4e-169 551.7 6.4 2e-41 140.5 0.0 4.9 4 0 0 4 4 4 4 Beta-ketoacyl synthase, C-terminal domain Acyl_transf_1 PF00698.16 CBZ49681.1 - 4.2e-151 502.7 2.8 4.6e-59 200.3 0.2 3.4 3 0 0 3 3 3 3 Acyl transferase domain ADH_zinc_N PF00107.21 CBZ49681.1 - 2.8e-78 259.7 0.5 3.5e-18 65.3 0.0 5.3 4 0 0 4 4 4 4 Zinc-binding dehydrogenase AMP-binding PF00501.23 CBZ49681.1 - 4.1e-75 252.7 0.0 8.4e-75 251.7 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.7 CBZ49681.1 - 3.4e-60 203.0 0.0 2e-55 187.4 0.0 5.3 5 0 0 5 5 5 1 Male sterility protein PP-binding PF00550.20 CBZ49681.1 - 2e-57 191.3 1.0 2.5e-14 53.2 0.0 6.0 5 0 0 5 5 5 4 Phosphopantetheine attachment site Epimerase PF01370.16 CBZ49681.1 - 2.5e-27 95.8 0.0 3.1e-08 33.3 0.0 6.3 6 0 0 6 6 5 5 NAD dependent epimerase/dehydratase family ADH_N PF08240.7 CBZ49681.1 - 7.3e-25 86.8 24.0 2.4e-06 27.2 0.0 7.6 8 0 0 8 8 8 4 Alcohol dehydrogenase GroES-like domain 3Beta_HSD PF01073.14 CBZ49681.1 - 4.5e-15 55.1 0.0 0.092 11.4 0.0 5.6 5 0 0 5 5 5 5 3-beta hydroxysteroid dehydrogenase/isomerase family Sulfotransfer_3 PF13469.1 CBZ49681.1 - 1.8e-14 54.9 0.6 1.8e-14 54.9 0.4 2.9 3 0 0 3 3 3 1 Sulfotransferase family Thiolase_N PF00108.18 CBZ49681.1 - 3.9e-14 52.2 7.7 0.00095 18.2 0.1 4.6 4 0 0 4 4 4 3 Thiolase, N-terminal domain adh_short_C2 PF13561.1 CBZ49681.1 - 1e-12 48.3 0.0 0.044 13.5 0.0 4.9 4 0 0 4 4 4 4 Enoyl-(Acyl carrier protein) reductase Polysacc_synt_2 PF02719.10 CBZ49681.1 - 5.4e-12 45.2 0.0 0.088 11.6 0.0 5.3 5 0 0 5 5 5 3 Polysaccharide biosynthesis protein Sulfotransfer_1 PF00685.22 CBZ49681.1 - 1.4e-10 40.8 0.1 3e-10 39.8 0.0 1.5 1 0 0 1 1 1 1 Sulfotransferase domain AlaDh_PNT_C PF01262.16 CBZ49681.1 - 0.00013 21.5 14.9 0.74 9.3 0.1 5.4 5 0 0 5 5 5 3 Alanine dehydrogenase/PNT, C-terminal domain DNA_gyraseB_C PF00986.16 CBZ49681.1 - 0.0017 18.0 0.0 9.9 6.0 0.0 4.3 4 0 0 4 4 4 0 DNA gyrase B subunit, carboxyl terminus DUF503 PF04456.7 CBZ49681.1 - 0.52 9.9 0.0 9.9 5.8 0.0 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF503) AMP-binding_C_2 PF14535.1 CBZ49681.1 - 0.6 10.1 0.0 2.3 8.3 0.0 2.1 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain Pox_D5 PF03288.11 CBZ49681.1 - 5.8 7.2 0.1 18 5.6 0.1 1.8 1 0 0 1 1 1 0 Poxvirus D5 protein-like CodY PF06018.9 CBZ49681.1 - 8.4 5.6 0.0 19 4.4 0.0 1.5 1 0 0 1 1 1 0 CodY GAF-like domain Methyltransf_32 PF13679.1 CBZ49682.1 - 5e-14 52.1 0.0 1.1e-13 51.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CBZ49682.1 - 1.5e-09 38.4 0.0 3.5e-09 37.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CBZ49682.1 - 3.9e-09 36.2 0.0 6.9e-09 35.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CBZ49682.1 - 2.3e-07 31.0 0.2 1.1e-06 28.8 0.1 2.2 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 CBZ49682.1 - 2.6e-07 30.1 0.0 4.5e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.7 CBZ49682.1 - 1.2e-06 28.9 0.0 3.9e-06 27.2 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 CBZ49682.1 - 1.2e-06 27.8 0.0 1.9e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 CBZ49682.1 - 4.1e-05 23.6 0.0 9.1e-05 22.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CBZ49682.1 - 7.4e-05 23.1 0.0 0.00041 20.7 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_2 PF00891.13 CBZ49682.1 - 0.00015 21.0 0.0 0.00025 20.3 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_4 PF02390.12 CBZ49682.1 - 0.00025 20.1 0.0 0.0005 19.1 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_23 PF13489.1 CBZ49682.1 - 0.019 14.6 0.0 0.037 13.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Nipped-B_C PF12830.2 CBZ49682.1 - 0.044 13.4 0.1 0.15 11.6 0.0 1.8 2 0 0 2 2 2 0 Sister chromatid cohesion C-terminus GidB PF02527.10 CBZ49682.1 - 0.059 12.4 0.0 0.1 11.7 0.0 1.3 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G zf-CCCH PF00642.19 CBZ49683.1 - 2.1e-10 40.0 14.0 2.6e-05 23.7 0.2 3.4 3 0 0 3 3 3 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Lipocalin_2 PF08212.7 CBZ49684.1 - 1.1e-18 67.4 0.0 1.5e-18 66.9 0.0 1.2 1 0 0 1 1 1 1 Lipocalin-like domain Actin PF00022.14 CBZ49685.1 - 6.8e-60 202.5 0.0 8.6e-60 202.2 0.0 1.1 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 CBZ49685.1 - 0.00037 19.1 0.0 0.00058 18.5 0.0 1.2 1 0 0 1 1 1 1 MreB/Mbl protein DRP PF06044.7 CBZ49686.1 - 4.7 6.1 0.0 7.3 5.4 0.0 1.1 1 0 0 1 1 1 0 Dam-replacing family Usp PF00582.21 CBZ49687.1 - 6.7e-12 45.7 0.9 5.8e-10 39.4 0.2 2.4 3 0 0 3 3 3 2 Universal stress protein family HhH-GPD PF00730.20 CBZ49688.1 - 0.0005 20.3 0.0 0.0039 17.4 0.0 2.3 2 0 0 2 2 2 1 HhH-GPD superfamily base excision DNA repair protein OGG_N PF07934.7 CBZ49688.1 - 0.0093 15.9 3.7 0.024 14.5 2.6 1.8 1 1 0 1 1 1 1 8-oxoguanine DNA glycosylase, N-terminal domain Daxx PF03344.10 CBZ49688.1 - 5.5 5.3 21.2 0.58 8.5 11.8 1.5 2 0 0 2 2 2 0 Daxx Family Ycf1 PF05758.7 CBZ49688.1 - 8.9 3.8 15.6 10 3.6 10.8 1.2 1 0 0 1 1 1 0 Ycf1 HSP70 PF00012.15 CBZ49689.1 - 3.2e-38 131.0 0.1 1.7e-17 62.6 0.0 3.5 2 1 2 4 4 4 3 Hsp70 protein TPR_11 PF13414.1 CBZ49689.1 - 6.8e-14 51.2 9.6 2.9e-07 30.0 0.2 2.6 1 1 1 2 2 2 2 TPR repeat TPR_1 PF00515.23 CBZ49689.1 - 5.9e-06 25.6 5.3 0.0016 17.9 0.1 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.12 CBZ49689.1 - 2.3e-05 23.9 4.9 0.0051 16.6 0.1 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 CBZ49689.1 - 3.1e-05 23.7 1.1 0.011 15.6 0.0 3.6 2 1 1 3 3 3 1 Fis1 C-terminal tetratricopeptide repeat TPR_9 PF13371.1 CBZ49689.1 - 0.0002 21.1 0.2 0.0002 21.1 0.1 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat Nitro_FeMo-Co PF02579.12 CBZ49689.1 - 0.061 13.4 0.6 0.16 12.0 0.4 1.7 1 0 0 1 1 1 0 Dinitrogenase iron-molybdenum cofactor TPR_14 PF13428.1 CBZ49689.1 - 7.8 7.4 12.6 1.7 9.5 0.2 4.7 3 1 2 5 5 5 0 Tetratricopeptide repeat BPL_LplA_LipB PF03099.14 CBZ49690.1 - 0.16 12.0 0.0 3 7.8 0.0 2.3 2 0 0 2 2 2 0 Biotin/lipoate A/B protein ligase family Ssl1 PF04056.9 CBZ49691.1 - 2.6e-49 167.4 0.0 3.1e-36 124.7 0.0 2.2 2 0 0 2 2 2 2 Ssl1-like C1_4 PF07975.7 CBZ49691.1 - 7.4e-07 29.0 15.4 7.4e-07 29.0 10.7 3.1 3 0 0 3 3 3 1 TFIIH C1-like domain VWA_2 PF13519.1 CBZ49691.1 - 0.00029 21.0 0.0 0.0006 19.9 0.0 1.6 1 1 0 1 1 1 1 von Willebrand factor type A domain Tfb4 PF03850.9 CBZ49691.1 - 0.01 15.1 2.9 0.28 10.4 4.2 1.7 2 0 0 2 2 2 1 Transcription factor Tfb4 LRR_4 PF12799.2 CBZ49692.1 - 1e-16 60.1 19.4 4.4e-08 32.5 0.2 5.6 2 1 4 6 6 6 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CBZ49692.1 - 1.8e-15 56.4 16.2 3.5e-06 26.6 0.5 4.8 4 1 1 5 5 5 4 Leucine rich repeat LRR_7 PF13504.1 CBZ49692.1 - 1.2e-06 27.7 19.7 0.69 10.3 0.1 7.1 7 0 0 7 7 7 3 Leucine rich repeat LRR_6 PF13516.1 CBZ49692.1 - 2e-06 27.2 21.1 0.68 10.1 0.1 6.7 6 1 0 6 6 6 3 Leucine Rich repeat LRR_1 PF00560.28 CBZ49692.1 - 4e-06 26.1 18.5 0.59 10.3 0.0 7.2 6 2 0 6 6 6 2 Leucine Rich Repeat LRR_9 PF14580.1 CBZ49692.1 - 1.2e-05 24.9 4.4 0.0044 16.5 0.1 2.8 1 1 2 3 3 3 2 Leucine-rich repeat CENP-T PF15511.1 CBZ49693.1 - 0.023 13.9 23.4 0.028 13.6 16.2 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T BUD22 PF09073.5 CBZ49693.1 - 0.83 8.6 31.7 1.2 8.1 21.9 1.3 1 0 0 1 1 1 0 BUD22 Daxx PF03344.10 CBZ49693.1 - 0.84 8.0 37.7 1.1 7.6 26.1 1.1 1 0 0 1 1 1 0 Daxx Family SDA1 PF05285.7 CBZ49693.1 - 1.6 7.9 31.8 2.2 7.4 22.0 1.3 1 0 0 1 1 1 0 SDA1 DUF4337 PF14235.1 CBZ49693.1 - 2 8.2 8.9 0.84 9.4 4.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) DUF2146 PF10220.4 CBZ49693.1 - 6.5 4.5 9.7 8.5 4.2 6.7 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2146) TPR_12 PF13424.1 CBZ49694.1 - 0.0039 17.0 0.7 0.95 9.4 0.1 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat HTH_41 PF14502.1 CBZ49694.1 - 0.04 13.5 0.1 0.078 12.6 0.1 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain TPR_16 PF13432.1 CBZ49694.1 - 0.099 13.3 7.2 3.6 8.3 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.1 CBZ49694.1 - 1.1 9.3 7.3 5.4 7.0 0.3 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat Sec1 PF00995.18 CBZ49696.1 - 4.5e-61 207.1 0.0 9.6e-26 90.5 0.0 3.8 3 1 0 3 3 3 3 Sec1 family HTH_40 PF14493.1 CBZ49696.1 - 1.1 9.4 2.9 46 4.3 0.0 3.2 3 0 0 3 3 3 0 Helix-turn-helix domain DEAD PF00270.24 CBZ49697.1 - 3.5e-38 130.7 0.0 7.7e-38 129.6 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CBZ49697.1 - 8.6e-21 73.5 0.0 2.2e-20 72.2 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 CBZ49697.1 - 0.055 13.2 4.4 0.091 12.5 0.0 3.2 2 2 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_22 PF13401.1 CBZ49697.1 - 0.1 12.7 0.2 0.66 10.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain TFIIF_alpha PF05793.7 CBZ49697.1 - 0.37 9.1 56.8 0.64 8.3 39.4 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF605 PF04652.11 CBZ49697.1 - 8.2 5.7 25.3 18 4.6 17.6 1.6 1 0 0 1 1 1 0 Vta1 like Patched PF02460.13 CBZ49698.1 - 7e-91 305.4 5.8 7.2e-50 169.7 4.2 2.2 2 0 0 2 2 2 2 Patched family Sterol-sensing PF12349.3 CBZ49698.1 - 1.8e-31 108.6 5.8 1.8e-31 108.6 4.0 2.4 2 0 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation ACR_tran PF00873.14 CBZ49698.1 - 0.011 13.1 8.9 0.016 12.6 6.2 1.1 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family Abi PF02517.11 CBZ49700.1 - 0.036 14.1 0.0 0.049 13.7 0.0 1.2 1 0 0 1 1 1 0 CAAX protease self-immunity HEAT_2 PF13646.1 CBZ49701.1 - 3.9e-16 59.0 3.4 0.016 15.4 0.0 6.5 3 2 3 6 6 6 5 HEAT repeats HEAT PF02985.17 CBZ49701.1 - 4.7e-13 48.0 19.0 0.00065 19.5 0.0 9.7 11 1 0 11 11 11 4 HEAT repeat HEAT_EZ PF13513.1 CBZ49701.1 - 6.9e-12 45.4 20.5 6e-09 36.1 0.0 8.7 8 2 1 9 9 9 1 HEAT-like repeat IBN_N PF03810.14 CBZ49701.1 - 0.00031 20.5 1.3 0.0023 17.8 0.2 3.0 3 0 0 3 3 3 1 Importin-beta N-terminal domain Vac14_Fab1_bd PF12755.2 CBZ49701.1 - 0.0021 18.4 0.6 4.2 7.8 0.0 4.6 3 1 1 4 4 4 1 Vacuolar 14 Fab1-binding region Cnd1 PF12717.2 CBZ49701.1 - 0.0031 17.3 1.8 13 5.5 0.0 5.0 4 2 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 Arm PF00514.18 CBZ49701.1 - 0.027 14.2 5.2 0.88 9.5 0.1 5.5 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat NAAA-beta PF15508.1 CBZ49701.1 - 0.03 14.6 0.1 0.43 10.9 0.0 2.8 3 0 0 3 3 3 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase MMS19_C PF12460.3 CBZ49701.1 - 0.21 10.2 4.3 5.4 5.6 0.0 3.7 4 1 0 4 4 4 0 RNAPII transcription regulator C-terminal tRNA-synt_2b PF00587.20 CBZ49702.1 - 4.2e-12 45.9 0.0 5e-10 39.2 0.0 3.0 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA-synt_His PF13393.1 CBZ49702.1 - 9.9e-11 41.2 0.3 0.012 14.7 0.0 5.1 4 1 0 4 4 4 3 Histidyl-tRNA synthetase RNase_T PF00929.19 CBZ49703.1 - 3.1e-05 24.3 0.0 0.00014 22.1 0.0 2.1 1 1 0 1 1 1 1 Exonuclease OB_NTP_bind PF07717.11 CBZ49704.1 - 1.3e-12 47.5 0.0 3.2e-12 46.2 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 CBZ49704.1 - 6e-12 45.2 0.0 1.4e-11 44.0 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HA2 PF04408.18 CBZ49704.1 - 5e-09 36.1 0.0 2.1e-08 34.0 0.0 2.2 1 0 0 1 1 1 1 Helicase associated domain (HA2) DEAD PF00270.24 CBZ49704.1 - 2.9e-05 23.6 0.0 6.5e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 CBZ49704.1 - 0.0069 16.5 0.0 0.027 14.6 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.1 CBZ49704.1 - 0.065 12.7 0.0 0.14 11.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain T2SE PF00437.15 CBZ49704.1 - 0.082 11.7 0.0 0.14 11.0 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein OST3_OST6 PF04756.8 CBZ49705.1 - 9.1e-11 41.5 0.4 9.1e-11 41.5 0.3 1.8 2 0 0 2 2 2 1 OST3 / OST6 family TRAM_LAG1_CLN8 PF03798.11 CBZ49705.1 - 3.9e-10 39.6 0.5 3.9e-10 39.6 0.3 3.0 4 0 0 4 4 4 1 TLC domain Kinase-like PF14531.1 CBZ49707.1 - 2.6e-73 246.5 0.0 3.2e-73 246.1 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Pkinase PF00069.20 CBZ49707.1 - 9e-05 21.7 0.0 0.00017 20.8 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ49707.1 - 0.073 12.1 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase PI3Ka PF00613.15 CBZ49708.1 - 2.3e-08 33.4 0.5 3.6e-08 32.8 0.4 1.2 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) Kinase-like PF14531.1 CBZ49709.1 - 1.3e-79 267.1 0.0 1.8e-79 266.7 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Pkinase PF00069.20 CBZ49709.1 - 7.9e-07 28.4 0.0 1.9e-06 27.2 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ49709.1 - 0.071 12.1 0.1 0.26 10.3 0.1 1.8 1 1 0 1 1 1 0 Protein tyrosine kinase PI3_PI4_kinase PF00454.22 CBZ49710.1 - 2e-25 89.6 0.1 2.1e-24 86.3 0.0 2.1 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.15 CBZ49710.1 - 7.8e-08 31.7 0.5 1.3e-07 30.9 0.4 1.2 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) UQ_con PF00179.21 CBZ49711.1 - 3.9e-21 74.9 0.0 7.7e-21 73.9 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.8 CBZ49711.1 - 0.041 13.5 0.2 0.072 12.7 0.2 1.3 1 0 0 1 1 1 0 UEV domain DNA_pol_phi PF04931.8 CBZ49711.1 - 2.8 5.5 4.6 4.5 4.9 3.2 1.2 1 0 0 1 1 1 0 DNA polymerase phi HA PF03457.9 CBZ49714.1 - 0.14 12.2 13.6 0.6 10.2 0.3 4.4 4 0 0 4 4 4 0 Helicase associated domain DUF2335 PF10097.4 CBZ49715.1 - 0.029 13.9 0.2 0.11 12.1 0.2 2.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2335) Replic_Relax PF13814.1 CBZ49715.1 - 0.04 13.7 1.4 0.059 13.2 0.1 1.8 2 0 0 2 2 2 0 Replication-relaxation CS PF04969.11 CBZ49717.1 - 0.00082 19.8 0.0 0.0015 19.0 0.0 1.4 1 0 0 1 1 1 1 CS domain Elongin_A PF06881.6 CBZ49717.1 - 0.0091 16.3 4.4 0.02 15.2 3.1 1.6 1 0 0 1 1 1 1 RNA polymerase II transcription factor SIII (Elongin) subunit A ClpS PF02617.12 CBZ49718.1 - 4.2e-15 55.2 0.0 7.5e-15 54.4 0.0 1.4 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS SpoIISA_toxin PF14171.1 CBZ49718.1 - 0.11 11.7 0.2 0.15 11.2 0.1 1.1 1 0 0 1 1 1 0 Toxin SpoIISA, type II toxin-antitoxin system Cytomega_UL84 PF06284.6 CBZ49718.1 - 0.22 9.9 0.9 0.31 9.4 0.6 1.3 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein cNMP_binding PF00027.24 CBZ49719.1 - 1.8e-13 50.1 0.0 3.8e-08 33.0 0.0 3.2 3 1 0 3 3 3 2 Cyclic nucleotide-binding domain Polysacc_deac_1 PF01522.16 CBZ49719.1 - 0.098 12.2 0.9 0.48 10.0 0.0 2.5 2 0 0 2 2 2 0 Polysaccharide deacetylase DUF4305 PF14146.1 CBZ49720.1 - 0.28 10.9 0.0 0.61 9.8 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4305) Pkinase PF00069.20 CBZ49721.1 - 6.5e-52 176.2 0.0 9.1e-52 175.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ49721.1 - 2.8e-21 75.7 0.0 3.9e-21 75.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_1 PF00036.27 CBZ49721.1 - 8.1e-13 46.6 6.7 3.3e-06 26.0 1.4 4.4 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.1 CBZ49721.1 - 2.9e-11 43.3 4.1 6.4e-06 26.2 0.1 3.0 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.1 CBZ49721.1 - 1.5e-09 36.8 6.6 0.0044 16.7 0.0 4.5 4 0 0 4 4 4 2 EF-hand domain EF-hand_5 PF13202.1 CBZ49721.1 - 3.3e-07 29.3 1.4 0.0086 15.3 0.2 2.8 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.1 CBZ49721.1 - 4.3e-07 29.4 7.2 9.1e-06 25.1 1.2 3.3 2 2 1 3 3 3 3 EF-hand domain pair DuffyBP_N PF12377.3 CBZ49721.1 - 0.21 11.8 0.6 0.49 10.6 0.4 1.5 1 0 0 1 1 1 0 Duffy binding protein N terminal TPR_11 PF13414.1 CBZ49723.1 - 1.1e-07 31.3 7.0 5.2e-06 26.0 0.1 3.0 3 0 0 3 3 3 2 TPR repeat TPR_1 PF00515.23 CBZ49723.1 - 5.5e-07 28.9 0.1 0.00049 19.5 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 CBZ49723.1 - 8.5e-05 22.1 0.2 0.16 11.9 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.1 CBZ49723.1 - 0.004 17.2 0.1 0.86 9.9 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat Lsr2 PF11774.3 CBZ49723.1 - 0.018 14.9 1.8 0.031 14.2 0.0 2.1 2 0 0 2 2 2 0 Lsr2 TPR_14 PF13428.1 CBZ49723.1 - 0.047 14.3 0.3 2 9.2 0.0 3.3 1 1 2 3 3 3 0 Tetratricopeptide repeat DUF4448 PF14610.1 CBZ49723.1 - 0.28 10.6 1.8 0.23 10.9 0.2 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4448) Oxidored_molyb PF00174.14 CBZ49724.1 - 4.8e-44 149.7 0.0 6.9e-44 149.2 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Cyt-b5 PF00173.23 CBZ49724.1 - 7.4e-15 54.5 0.0 1.3e-14 53.7 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain HECT PF00632.20 CBZ49725.1 - 3.5e-91 305.6 0.0 5e-91 305.1 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) DUF908 PF06012.7 CBZ49725.1 - 8.9e-84 281.5 0.3 1.6e-82 277.4 0.0 2.8 3 0 0 3 3 3 1 Domain of Unknown Function (DUF908) DUF913 PF06025.7 CBZ49725.1 - 1.1e-17 63.8 14.2 9.1e-10 37.8 0.0 4.7 5 0 0 5 5 5 2 Domain of Unknown Function (DUF913) DUF4414 PF14377.1 CBZ49725.1 - 1.3e-16 60.3 7.7 1.3e-16 60.3 5.3 3.7 2 1 1 3 3 3 1 Domain of unknown function (DUF4414) UBA PF00627.26 CBZ49725.1 - 2.4e-07 30.4 0.6 6.8e-07 28.9 0.4 1.8 1 0 0 1 1 1 1 UBA/TS-N domain DUF46 PF01864.12 CBZ49725.1 - 5.9 6.7 0.1 12 5.7 0.1 1.4 1 0 0 1 1 1 0 Putative integral membrane protein DUF46 Ubie_methyltran PF01209.13 CBZ49726.1 - 1.9e-78 262.8 0.0 5.8e-54 182.6 0.0 2.5 2 1 0 2 2 2 2 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.7 CBZ49726.1 - 1.1e-15 57.8 0.0 6e-13 49.0 0.0 2.9 2 1 1 3 3 3 1 Methyltransferase domain Methyltransf_25 PF13649.1 CBZ49726.1 - 1.7e-09 37.9 0.3 0.0016 18.7 0.0 3.4 2 1 1 3 3 3 2 Methyltransferase domain Methyltransf_31 PF13847.1 CBZ49726.1 - 5e-09 35.9 0.0 3.5e-05 23.4 0.0 3.2 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_23 PF13489.1 CBZ49726.1 - 4.2e-08 33.0 0.0 8.1e-08 32.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CBZ49726.1 - 7.4e-07 29.5 0.0 6.3e-05 23.3 0.0 3.3 3 1 0 3 3 3 1 Methyltransferase domain Methyltransf_18 PF12847.2 CBZ49726.1 - 1.8e-05 25.2 0.0 0.036 14.6 0.0 3.0 2 1 0 2 2 2 2 Methyltransferase domain Methyltransf_26 PF13659.1 CBZ49726.1 - 3.7e-05 23.7 0.0 0.00011 22.2 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.10 CBZ49726.1 - 0.00028 20.5 0.0 0.00072 19.2 0.0 1.6 1 0 0 1 1 1 1 Hypothetical methyltransferase WD40 PF00400.27 CBZ49727.1 - 3.5e-38 128.1 17.6 1.2e-10 40.8 0.2 8.9 9 0 0 9 9 9 6 WD domain, G-beta repeat Utp12 PF04003.7 CBZ49727.1 - 1.7e-09 37.5 1.8 3.1e-09 36.7 1.3 1.4 1 0 0 1 1 1 1 Dip2/Utp12 Family SGL PF08450.7 CBZ49727.1 - 0.051 12.9 0.0 1.3 8.2 0.0 2.9 2 1 1 3 3 3 0 SMP-30/Gluconolaconase/LRE-like region Cytochrom_D1 PF02239.11 CBZ49727.1 - 0.15 10.3 0.0 0.78 7.9 0.0 2.1 2 0 0 2 2 2 0 Cytochrome D1 heme domain Apolipoprotein PF01442.13 CBZ49728.1 - 0.0055 16.2 6.4 0.052 13.0 4.5 2.2 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain HrpE PF06188.7 CBZ49728.1 - 0.0059 16.3 0.7 0.0059 16.3 0.5 2.0 1 1 0 2 2 2 1 HrpE/YscL/FliH and V-type ATPase subunit E Paramyxo_PCT PF14320.1 CBZ49728.1 - 0.017 14.0 0.0 0.019 13.8 0.0 1.1 1 0 0 1 1 1 0 Phosphoprotein P region PCT disordered DUF2760 PF10816.3 CBZ49728.1 - 0.034 13.6 0.2 0.067 12.7 0.1 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF2760) ISG65-75 PF11727.3 CBZ49728.1 - 0.037 13.0 1.3 0.064 12.2 0.9 1.4 1 0 0 1 1 1 0 Invariant surface glycoprotein MCP_N PF05581.7 CBZ49728.1 - 0.057 13.5 2.6 0.16 12.1 0.1 2.4 1 1 1 2 2 2 0 Vibrio chemotaxis protein N terminus SICA_alpha PF12887.2 CBZ49728.1 - 0.11 12.1 3.8 2.1 8.0 0.6 2.1 2 0 0 2 2 2 0 SICA extracellular alpha domain zf-UBR PF02207.15 CBZ49729.1 - 7.2e-17 60.8 11.6 7.2e-17 60.8 8.0 2.8 3 0 0 3 3 3 1 Putative zinc finger in N-recognin (UBR box) Ribosomal_60s PF00428.14 CBZ49730.1 - 0.011 16.1 0.4 0.011 16.1 0.3 3.3 3 0 0 3 3 3 0 60s Acidic ribosomal protein Peptidase_M13_N PF05649.8 CBZ49731.1 - 2.3e-92 310.0 0.0 3e-92 309.6 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.16 CBZ49731.1 - 1.4e-42 145.2 0.0 8.6e-21 74.0 0.0 2.7 1 1 1 2 2 2 2 Peptidase family M13 Peptidase_M48 PF01435.13 CBZ49731.1 - 0.099 12.1 0.0 0.26 10.8 0.0 1.6 1 0 0 1 1 1 0 Peptidase family M48 MORN_2 PF07661.8 CBZ49731.1 - 0.88 9.8 2.8 2 8.7 1.3 2.1 2 0 0 2 2 2 0 MORN repeat variant SET PF00856.23 CBZ49734.1 - 5.4e-23 82.0 2.9 1.7e-22 80.4 0.1 3.7 2 0 0 2 2 2 1 SET domain SAG PF04092.8 CBZ49735.1 - 9.4e-46 155.2 10.6 2.6e-29 102.1 1.4 2.3 2 1 0 2 2 2 2 SRS domain SAG PF04092.8 CBZ49736.1 - 1.8e-41 141.3 10.0 2.2e-29 102.3 1.2 2.6 2 1 1 3 3 3 2 SRS domain SAG PF04092.8 CBZ49737.1 - 8.6e-45 152.1 11.1 3.2e-29 101.8 1.2 2.3 2 0 0 2 2 2 2 SRS domain Pilin PF00114.14 CBZ49737.1 - 4.1 8.1 10.0 0.3 11.8 1.7 2.8 3 1 0 3 3 3 0 Pilin (bacterial filament) SAG PF04092.8 CBZ49738.1 - 1e-45 155.1 13.9 2.6e-28 98.8 0.5 2.3 2 0 0 2 2 2 2 SRS domain SAG PF04092.8 CBZ49739.1 - 6.9e-44 149.2 12.0 2.6e-29 102.1 1.4 2.5 2 1 0 2 2 2 2 SRS domain C2 PF00168.25 CBZ49741.1 - 9.5e-28 95.8 0.2 1.9e-10 40.4 0.0 4.7 4 0 0 4 4 4 3 C2 domain DUF972 PF06156.8 CBZ49741.1 - 0.23 11.7 0.1 0.53 10.6 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF972) Got1 PF04178.7 CBZ49742.1 - 5.6e-18 65.1 12.1 6.5e-18 64.9 8.4 1.0 1 0 0 1 1 1 1 Got1/Sft2-like family DUF308 PF03729.8 CBZ49742.1 - 0.12 12.3 15.0 0.11 12.5 8.1 2.2 1 1 1 2 2 2 0 Short repeat of unknown function (DUF308) COPI_assoc PF08507.5 CBZ49742.1 - 0.58 9.8 4.6 0.23 11.1 1.5 1.6 1 1 1 2 2 2 0 COPI associated protein FA_desaturase PF00487.19 CBZ49742.1 - 6.6 6.0 7.0 8.2 5.7 4.9 1.1 1 0 0 1 1 1 0 Fatty acid desaturase DUF4631 PF15450.1 CBZ49743.1 - 0.0012 17.2 2.4 0.0014 17.0 1.7 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4631) Filament PF00038.16 CBZ49743.1 - 0.0041 16.6 5.6 0.0054 16.2 3.9 1.2 1 0 0 1 1 1 1 Intermediate filament protein HOOK PF05622.7 CBZ49743.1 - 0.0064 14.3 4.1 0.0077 14.1 2.8 1.0 1 0 0 1 1 1 1 HOOK protein DUF842 PF05811.8 CBZ49743.1 - 0.0068 15.8 0.5 0.009 15.4 0.4 1.2 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF842) Mer2 PF09074.5 CBZ49743.1 - 0.007 16.3 4.4 0.0077 16.1 2.2 1.6 1 1 1 2 2 2 1 Mer2 Taxilin PF09728.4 CBZ49743.1 - 0.0099 14.9 5.4 0.017 14.2 3.8 1.3 1 0 0 1 1 1 1 Myosin-like coiled-coil protein ADIP PF11559.3 CBZ49743.1 - 0.014 15.3 11.2 0.016 15.0 7.7 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding EzrA PF06160.7 CBZ49743.1 - 0.025 12.8 6.9 0.03 12.5 4.8 1.0 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA SlyX PF04102.7 CBZ49743.1 - 0.026 14.8 3.7 0.062 13.6 2.5 1.6 1 0 0 1 1 1 0 SlyX Sec5 PF15469.1 CBZ49743.1 - 0.034 13.8 1.7 0.039 13.6 1.2 1.1 1 0 0 1 1 1 0 Exocyst complex component Sec5 APG6 PF04111.7 CBZ49743.1 - 0.041 12.9 8.8 0.051 12.6 6.1 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 GldM_N PF12081.3 CBZ49743.1 - 0.047 13.2 3.4 0.06 12.8 2.4 1.1 1 0 0 1 1 1 0 GldM N-terminal domain Mnd1 PF03962.10 CBZ49743.1 - 0.048 13.3 4.8 0.055 13.1 3.3 1.1 1 0 0 1 1 1 0 Mnd1 family DUF4200 PF13863.1 CBZ49743.1 - 0.056 13.3 8.2 0.07 13.0 5.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) YbfN PF13982.1 CBZ49743.1 - 0.061 13.5 0.1 0.15 12.2 0.0 1.6 2 0 0 2 2 2 0 YbfN-like lipoprotein Metal_resist PF13801.1 CBZ49743.1 - 0.064 13.2 0.5 0.064 13.2 0.3 1.9 2 0 0 2 2 2 0 Heavy-metal resistance CorA PF01544.13 CBZ49743.1 - 0.072 12.1 5.2 0.088 11.8 3.6 1.1 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein OmpH PF03938.9 CBZ49743.1 - 0.097 12.5 3.8 0.12 12.2 2.7 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Erp_C PF06780.6 CBZ49743.1 - 0.12 12.2 4.9 0.14 11.9 3.4 1.2 1 0 0 1 1 1 0 Erp protein C-terminus IncA PF04156.9 CBZ49743.1 - 0.17 11.4 8.4 0.22 11.0 5.9 1.2 1 0 0 1 1 1 0 IncA protein DUF972 PF06156.8 CBZ49743.1 - 0.24 11.7 3.9 0.36 11.1 2.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF972) DUF342 PF03961.8 CBZ49743.1 - 0.28 9.5 4.9 0.33 9.3 3.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Allexi_40kDa PF05549.6 CBZ49743.1 - 0.32 10.2 4.0 0.38 10.0 2.8 1.1 1 0 0 1 1 1 0 Allexivirus 40kDa protein AAA_13 PF13166.1 CBZ49743.1 - 0.33 9.3 7.0 0.37 9.2 4.9 1.0 1 0 0 1 1 1 0 AAA domain V_ATPase_I PF01496.14 CBZ49743.1 - 0.48 8.2 3.8 0.55 8.0 2.7 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Tho2 PF11262.3 CBZ49743.1 - 0.49 9.3 3.7 0.57 9.1 2.6 1.1 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Seryl_tRNA_N PF02403.17 CBZ49743.1 - 0.75 9.8 8.7 1.5 8.8 5.0 1.5 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF724 PF05266.9 CBZ49743.1 - 0.87 9.1 5.7 1.2 8.7 3.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Phytochelatin_C PF09328.5 CBZ49743.1 - 0.89 8.9 5.0 0.65 9.4 2.4 1.5 1 1 1 2 2 2 0 Domain of unknown function (DUF1984) DivIVA PF05103.8 CBZ49743.1 - 1.1 9.2 9.4 5.1 7.1 5.3 2.2 1 1 1 2 2 2 0 DivIVA protein GrpE PF01025.14 CBZ49743.1 - 1.4 8.4 7.2 1.9 8.0 4.6 1.4 1 1 0 1 1 1 0 GrpE CCDC-167 PF15188.1 CBZ49743.1 - 2 8.4 8.9 0.97 9.4 4.4 1.7 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 167 COG2 PF06148.6 CBZ49743.1 - 2.6 7.9 5.7 11 5.8 3.9 1.8 1 1 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 Atg14 PF10186.4 CBZ49743.1 - 3.5 6.4 8.7 4.3 6.1 6.0 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DivIC PF04977.10 CBZ49743.1 - 5.1 6.6 10.0 9.4 5.8 6.3 1.9 1 1 1 2 2 2 0 Septum formation initiator TerD PF02342.13 CBZ49746.1 - 3.6e-09 36.2 0.0 8.4e-09 35.0 0.0 1.6 1 1 0 1 1 1 1 TerD domain DUF1546 PF07571.8 CBZ49747.1 - 1.6e-07 31.3 0.1 5.4e-07 29.6 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1546) TAF PF02969.12 CBZ49747.1 - 0.0035 17.2 0.1 0.0081 16.0 0.0 1.5 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) Ctr PF04145.10 CBZ49747.1 - 0.2 11.7 1.3 4.5 7.2 0.0 2.8 2 0 0 2 2 2 0 Ctr copper transporter family DUF544 PF04424.8 CBZ49748.1 - 9.5e-18 64.1 0.0 1.6e-17 63.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF544) Macoilin PF09726.4 CBZ49748.1 - 2.5 6.2 12.2 4.2 5.5 8.5 1.3 1 0 0 1 1 1 0 Transmembrane protein DUF2217 PF10265.4 CBZ49748.1 - 7.1 5.2 6.8 12 4.5 4.7 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) Tox-REase-5 PF15648.1 CBZ49751.1 - 0.034 14.4 0.0 0.081 13.2 0.0 1.7 1 0 0 1 1 1 0 Restriction endonuclease fold toxin 5 NDK PF00334.14 CBZ49752.1 - 6.7e-55 184.5 0.0 7.7e-55 184.3 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase NUFIP1 PF10453.4 CBZ49752.1 - 0.12 11.8 0.1 0.22 11.0 0.1 1.3 1 0 0 1 1 1 0 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) UBA PF00627.26 CBZ49753.1 - 6.6e-24 83.0 3.6 1.3e-12 47.1 0.0 2.5 2 0 0 2 2 2 2 UBA/TS-N domain XPC-binding PF09280.6 CBZ49753.1 - 6.8e-24 83.1 8.4 1.4e-23 82.1 5.8 1.5 1 0 0 1 1 1 1 XPC-binding domain ubiquitin PF00240.18 CBZ49753.1 - 3e-11 42.5 0.0 5.1e-11 41.8 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD_2 PF13881.1 CBZ49753.1 - 1.7e-05 24.6 0.0 3.2e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like RuvA_C PF07499.8 CBZ49753.1 - 0.0002 21.4 0.2 0.82 9.8 0.0 3.3 3 0 0 3 3 3 2 RuvA, C-terminal domain DUF2407 PF10302.4 CBZ49753.1 - 0.0093 16.1 0.0 0.017 15.2 0.0 1.5 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain DUF3173 PF11372.3 CBZ49753.1 - 0.064 12.8 0.0 1.6 8.3 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3173) MSA-2c PF12238.3 CBZ49753.1 - 0.47 10.1 1.9 0.81 9.3 1.3 1.4 1 0 0 1 1 1 0 Merozoite surface antigen 2c Vps54 PF07928.7 CBZ49754.1 - 3.9e-13 49.6 0.7 8.9e-13 48.5 0.5 1.6 1 0 0 1 1 1 1 Vps54-like protein DUF2450 PF10475.4 CBZ49754.1 - 6e-07 28.6 0.3 1e-06 27.8 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function N-terminal domain (DUF2450) NUC153 PF08159.7 CBZ49755.1 - 0.011 15.3 0.3 0.021 14.4 0.2 1.4 1 0 0 1 1 1 0 NUC153 domain IncA PF04156.9 CBZ49755.1 - 0.78 9.3 3.5 1.3 8.6 2.4 1.2 1 0 0 1 1 1 0 IncA protein TBCA PF02970.11 CBZ49756.1 - 3.6e-26 91.0 2.9 5.2e-26 90.5 2.0 1.3 1 0 0 1 1 1 1 Tubulin binding cofactor A Kinesin-relat_1 PF12711.2 CBZ49756.1 - 0.17 12.3 2.4 0.29 11.5 1.3 1.6 1 1 0 1 1 1 0 Kinesin motor LRR_4 PF12799.2 CBZ49757.1 - 1.5e-11 43.6 18.0 1.2e-05 24.8 0.3 5.2 5 1 0 5 5 5 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CBZ49757.1 - 1.2e-07 31.3 19.1 3.2e-05 23.5 1.7 4.7 4 0 0 4 4 4 2 Leucine rich repeat LRR_1 PF00560.28 CBZ49757.1 - 0.00021 20.8 18.5 0.24 11.5 0.1 7.5 7 0 0 7 7 7 2 Leucine Rich Repeat LRR_6 PF13516.1 CBZ49757.1 - 1.1 9.5 14.5 1.2 9.4 0.1 5.5 6 0 0 6 6 6 0 Leucine Rich repeat LRR_7 PF13504.1 CBZ49757.1 - 2.3 8.7 20.4 1.5 9.3 0.1 6.6 6 0 0 6 6 6 0 Leucine rich repeat TMF_DNA_bd PF12329.3 CBZ49759.1 - 0.025 14.3 0.5 0.025 14.3 0.4 4.3 3 1 1 4 4 4 0 TATA element modulatory factor 1 DNA binding EzrA PF06160.7 CBZ49759.1 - 0.11 10.6 22.2 0.22 9.6 15.4 1.4 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA DUF948 PF06103.6 CBZ49759.1 - 0.5 10.2 4.4 0.38 10.6 1.3 2.1 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF573 PF04504.9 CBZ49759.1 - 1.4 9.2 5.1 16 5.8 0.9 2.8 3 0 0 3 3 3 0 Protein of unknown function, DUF573 V_ATPase_I PF01496.14 CBZ49759.1 - 2.3 5.9 21.8 3.2 5.4 14.7 1.4 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family TMPIT PF07851.8 CBZ49759.1 - 4.4 6.2 19.2 0.69 8.9 9.5 2.0 2 0 0 2 2 2 0 TMPIT-like protein DUF3584 PF12128.3 CBZ49759.1 - 8.3 3.5 33.3 15 2.7 23.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Adap_comp_sub PF00928.16 CBZ49760.1 - 2.2e-50 171.1 0.0 1.1e-49 168.9 0.0 1.8 1 1 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 CBZ49760.1 - 2.4e-05 24.0 0.0 4.2e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DUF572 PF04502.8 CBZ49761.1 - 9.3e-85 284.6 9.6 9.3e-85 284.6 6.6 1.4 1 1 0 1 1 1 1 Family of unknown function (DUF572) TPR_11 PF13414.1 CBZ49762.1 - 4.8e-25 86.9 12.8 2.4e-08 33.4 0.6 6.4 4 1 4 8 8 8 6 TPR repeat TPR_2 PF07719.12 CBZ49762.1 - 2.4e-24 83.2 17.2 0.012 15.4 0.0 8.9 9 0 0 9 9 9 6 Tetratricopeptide repeat TPR_12 PF13424.1 CBZ49762.1 - 1.4e-18 66.5 15.0 0.00046 20.0 0.2 6.6 3 1 5 8 8 8 6 Tetratricopeptide repeat TPR_16 PF13432.1 CBZ49762.1 - 7.1e-16 58.4 23.7 2e-05 25.1 0.4 6.8 6 1 2 8 8 8 4 Tetratricopeptide repeat TPR_6 PF13174.1 CBZ49762.1 - 1.4e-15 56.6 4.3 0.06 13.8 0.0 7.9 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_1 PF00515.23 CBZ49762.1 - 2.4e-15 55.3 12.6 0.17 11.5 0.0 7.3 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_14 PF13428.1 CBZ49762.1 - 2.3e-11 43.2 12.8 0.027 15.0 0.0 8.1 5 2 3 8 8 8 3 Tetratricopeptide repeat TPR_19 PF14559.1 CBZ49762.1 - 2.5e-10 40.5 5.5 0.032 14.5 0.0 6.0 4 2 3 7 7 7 5 Tetratricopeptide repeat TPR_7 PF13176.1 CBZ49762.1 - 3.1e-09 35.9 8.1 0.4 10.6 0.0 6.4 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_8 PF13181.1 CBZ49762.1 - 4.4e-09 35.4 3.2 2 8.3 0.0 7.5 8 0 0 8 8 8 2 Tetratricopeptide repeat Apc3 PF12895.2 CBZ49762.1 - 9.4e-08 32.0 10.5 0.0029 17.7 0.2 4.9 4 1 1 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.1 CBZ49762.1 - 4.6e-06 26.3 6.5 2.2 8.3 0.0 6.2 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_17 PF13431.1 CBZ49762.1 - 0.00073 19.5 3.5 6.2 7.2 0.0 5.2 6 0 0 6 6 4 1 Tetratricopeptide repeat TPR_9 PF13371.1 CBZ49762.1 - 0.02 14.7 4.8 2.7 7.8 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat Coatomer_E PF04733.9 CBZ49762.1 - 0.039 13.1 0.0 0.45 9.6 0.0 2.2 2 0 0 2 2 2 0 Coatomer epsilon subunit DEAD PF00270.24 CBZ49763.1 - 3.7e-42 143.6 0.0 5.8e-42 143.0 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CBZ49763.1 - 6.9e-18 64.2 0.0 1.5e-16 60.0 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SPRY PF00622.23 CBZ49763.1 - 3.5e-17 62.6 0.0 5.9e-17 61.9 0.0 1.3 1 0 0 1 1 1 1 SPRY domain SNF2_N PF00176.18 CBZ49763.1 - 0.29 9.8 0.0 0.37 9.5 0.0 1.2 1 0 0 1 1 1 0 SNF2 family N-terminal domain Ribosomal_S4e PF00900.15 CBZ49764.1 - 9.9e-31 105.2 0.0 2.6e-30 103.8 0.0 1.8 1 0 0 1 1 1 1 Ribosomal family S4e RS4NT PF08071.7 CBZ49764.1 - 4.7e-19 67.9 10.6 4.8e-19 67.9 5.6 2.3 3 0 0 3 3 3 1 RS4NT (NUC023) domain S4 PF01479.20 CBZ49764.1 - 6.2e-07 28.7 0.1 1.3e-06 27.7 0.1 1.6 1 0 0 1 1 1 1 S4 domain KOW PF00467.24 CBZ49764.1 - 8.9e-05 22.0 1.1 8.9e-05 22.0 0.8 2.5 3 0 0 3 3 3 1 KOW motif Aminotran_4 PF01063.14 CBZ49764.1 - 0.059 12.8 0.0 0.073 12.5 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class IV RtcB PF01139.12 CBZ49765.1 - 5.6e-145 483.5 0.1 7e-145 483.2 0.1 1.0 1 0 0 1 1 1 1 tRNA-splicing ligase RtcB ACP_syn_III_C PF08541.5 CBZ49765.1 - 0.0016 18.4 0.1 0.0038 17.2 0.0 1.7 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal Ras PF00071.17 CBZ49766.1 - 2.6e-45 153.7 0.0 3.2e-45 153.4 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CBZ49766.1 - 1e-17 64.7 0.0 1.6e-17 64.0 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CBZ49766.1 - 5.9e-13 48.4 0.0 8.6e-13 47.8 0.0 1.2 1 1 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 CBZ49766.1 - 6.9e-06 25.3 0.0 9.6e-06 24.8 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 CBZ49766.1 - 1.1e-05 24.9 0.0 2.1e-05 24.0 0.0 1.4 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 CBZ49766.1 - 0.0017 18.2 0.0 0.0027 17.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.22 CBZ49766.1 - 0.0037 17.5 0.0 0.0065 16.7 0.0 1.4 1 0 0 1 1 1 1 ABC transporter DUF258 PF03193.11 CBZ49766.1 - 0.0053 15.9 0.0 0.0099 15.0 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 CBZ49766.1 - 0.0098 15.3 0.0 0.022 14.3 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.1 CBZ49766.1 - 0.026 14.6 0.0 0.21 11.7 0.0 2.1 2 1 0 2 2 2 0 AAA domain AAA_24 PF13479.1 CBZ49766.1 - 0.064 12.8 0.0 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 CBZ49766.1 - 0.074 12.7 0.0 0.18 11.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Hpr_kinase_C PF07475.7 CBZ49766.1 - 0.097 11.9 0.1 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 HPr Serine kinase C-terminal domain AAA_16 PF13191.1 CBZ49766.1 - 0.1 12.6 0.0 0.19 11.6 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain IstB_IS21 PF01695.12 CBZ49766.1 - 0.13 11.6 0.0 0.21 11.0 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein CbiA PF01656.18 CBZ49766.1 - 0.16 11.4 0.2 5.7 6.2 0.0 2.3 2 1 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain GCC2_GCC3 PF07699.8 CBZ49767.1 - 6e-10 38.5 426.2 0.00071 19.1 2.0 41.6 32 9 9 42 42 42 28 GCC2 and GCC3 PP2C PF00481.16 CBZ49768.1 - 2.5e-07 30.3 0.0 1.8e-06 27.5 0.0 2.0 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 CBZ49768.1 - 3.8e-05 23.1 0.0 0.00013 21.4 0.0 1.8 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 CBZ49768.1 - 0.012 15.2 0.0 0.08 12.6 0.0 2.2 2 0 0 2 2 2 0 Stage II sporulation protein E (SpoIIE) Tubulin PF00091.20 CBZ49769.1 - 1.5e-38 132.8 0.0 1.5e-27 96.8 0.0 2.6 1 1 0 2 2 2 2 Tubulin/FtsZ family, GTPase domain Tubulin_2 PF13809.1 CBZ49769.1 - 0.11 11.4 0.0 0.17 10.7 0.0 1.2 1 0 0 1 1 1 0 Tubulin like Kinase-like PF14531.1 CBZ49770.1 - 4.6e-24 84.8 0.0 6.4e-24 84.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase PF00069.20 CBZ49770.1 - 5e-09 35.6 0.0 9.3e-09 34.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain DUF3804 PF12707.2 CBZ49770.1 - 0.0074 15.8 0.0 0.12 11.9 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3804) Pyr_redox_2 PF07992.9 CBZ49771.1 - 9.8e-24 84.3 0.0 2e-23 83.3 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Rieske PF00355.21 CBZ49771.1 - 1.3e-15 56.7 0.0 3e-15 55.5 0.0 1.7 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Pyr_redox PF00070.22 CBZ49771.1 - 9.8e-13 48.3 4.3 2e-10 40.9 0.1 3.0 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Rieske_2 PF13806.1 CBZ49771.1 - 2.1e-11 43.4 0.2 2.7e-10 39.9 0.0 2.7 3 0 0 3 3 3 1 Rieske-like [2Fe-2S] domain DAO PF01266.19 CBZ49771.1 - 5.6e-08 32.0 3.2 5.2e-05 22.3 0.0 3.6 4 0 0 4 4 4 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 CBZ49771.1 - 6.2e-07 29.6 0.0 4e-05 23.7 0.0 2.7 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Reductase_C PF14759.1 CBZ49771.1 - 1e-06 28.8 0.1 7.1e-06 26.2 0.0 2.6 2 0 0 2 2 2 1 Reductase C-terminal ThiF PF00899.16 CBZ49771.1 - 0.018 14.8 0.2 0.16 11.7 0.0 2.5 2 1 0 2 2 2 0 ThiF family Shikimate_DH PF01488.15 CBZ49771.1 - 0.037 14.1 0.0 3.9 7.5 0.0 2.6 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase NAD_binding_8 PF13450.1 CBZ49771.1 - 0.16 12.0 1.8 2 8.5 0.2 2.7 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain RF-1 PF00472.15 CBZ49772.1 - 9.6e-32 109.1 2.3 9.6e-32 109.1 1.6 3.3 3 0 0 3 3 3 1 RF-1 domain PCRF PF03462.13 CBZ49772.1 - 7.7e-19 67.5 5.7 7.8e-18 64.2 0.4 3.0 3 0 0 3 3 3 2 PCRF domain tRNA-synt_1 PF00133.17 CBZ49773.1 - 7.1e-219 727.7 0.0 9.8e-219 727.2 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 CBZ49773.1 - 2e-23 82.8 0.0 7.6e-23 80.9 0.0 1.9 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 CBZ49773.1 - 1.7e-17 63.1 1.7 3.5e-07 29.2 0.4 4.0 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.14 CBZ49773.1 - 0.012 14.8 0.0 0.029 13.4 0.0 1.6 1 0 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain Kinesin PF00225.18 CBZ49774.1 - 1.2e-105 352.9 1.1 1.2e-105 352.9 0.7 2.3 2 1 0 2 2 2 1 Kinesin motor domain PIF1 PF05970.9 CBZ49774.1 - 0.0026 16.7 0.3 0.0088 15.0 0.2 1.8 1 0 0 1 1 1 1 PIF1-like helicase Fmp27_WPPW PF10359.4 CBZ49774.1 - 0.066 11.6 11.7 0.12 10.7 8.1 1.5 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Bac_DnaA PF00308.13 CBZ49774.1 - 0.4 10.2 0.0 0.4 10.2 0.0 2.4 2 0 0 2 2 2 0 Bacterial dnaA protein Skp1 PF01466.14 CBZ49775.1 - 4.2e-35 119.6 1.3 6.3e-35 119.0 0.9 1.3 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.10 CBZ49775.1 - 3.6e-19 68.6 1.2 6.8e-19 67.7 0.8 1.5 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain BTB PF00651.26 CBZ49775.1 - 0.0086 16.0 0.1 0.027 14.4 0.1 1.9 1 1 0 1 1 1 1 BTB/POZ domain dsDNA_bind PF01984.15 CBZ49776.1 - 6.1e-25 87.2 8.2 7e-25 87.0 5.6 1.0 1 0 0 1 1 1 1 Double-stranded DNA-binding domain Kinase-like PF14531.1 CBZ49777.1 - 1.7e-13 50.1 0.0 4.4e-13 48.8 0.0 1.7 1 1 0 1 1 1 1 Kinase-like Pkinase PF00069.20 CBZ49777.1 - 2.5e-07 30.1 0.1 7.9e-07 28.4 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Apc13p PF05839.6 CBZ49777.1 - 0.026 14.4 0.0 0.086 12.8 0.0 1.8 1 0 0 1 1 1 0 Apc13p protein BRK PF07533.11 CBZ49777.1 - 0.087 12.3 0.1 0.25 10.8 0.1 1.7 1 0 0 1 1 1 0 BRK domain CDP-OH_P_transf PF01066.16 CBZ49778.1 - 3e-16 59.5 14.2 1.1e-15 57.7 9.8 2.0 1 1 0 1 1 1 1 CDP-alcohol phosphatidyltransferase MASE2 PF05230.6 CBZ49778.1 - 2.3 8.2 8.2 6.1 6.8 0.3 3.2 3 0 0 3 3 3 0 MASE2 domain Cornichon PF03311.9 CBZ49778.1 - 4.8 7.3 7.1 1.2 9.2 0.1 2.7 3 1 0 3 3 3 0 Cornichon protein Nrap PF03813.9 CBZ49779.1 - 1e-76 258.3 0.1 3.1e-26 91.2 0.0 7.6 6 2 1 7 7 7 6 Nrap protein PCI PF01399.22 CBZ49780.1 - 6.4e-12 45.7 0.0 1e-07 32.2 0.0 2.8 3 0 0 3 3 3 2 PCI domain DnaJ PF00226.26 CBZ49781.1 - 2e-22 78.6 0.7 3.6e-22 77.8 0.5 1.4 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 CBZ49781.1 - 5.5e-22 77.4 2.5 5.7e-14 51.7 0.0 3.3 3 0 0 3 3 3 3 DnaJ C terminal domain Glyco_transf_17 PF04724.8 CBZ49782.1 - 7.1e-16 58.1 0.1 4e-14 52.4 0.0 2.1 2 0 0 2 2 2 2 Glycosyltransferase family 17 Glyco_hydro_42M PF08532.5 CBZ49782.1 - 0.074 12.1 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 Beta-galactosidase trimerisation domain Enkurin PF13864.1 CBZ49786.1 - 1.8e-24 85.7 0.1 2.3e-24 85.4 0.1 1.1 1 0 0 1 1 1 1 Calmodulin-binding Pkinase PF00069.20 CBZ49788.1 - 4.2e-61 206.3 0.0 7.9e-61 205.4 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ49788.1 - 1.4e-28 99.6 0.0 4.4e-23 81.6 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase MORN PF02493.15 CBZ49789.1 - 7.9e-49 160.5 54.0 5.8e-07 28.8 0.0 10.3 9 1 0 9 9 9 9 MORN repeat TFIIIC_sub6 PF10419.4 CBZ49789.1 - 1.9 7.9 9.5 12 5.4 0.0 4.9 6 0 0 6 6 6 0 TFIIIC subunit CBM_5_12 PF02839.9 CBZ49789.1 - 5.7 6.6 9.6 0.51 9.9 0.1 3.4 3 0 0 3 3 3 0 Carbohydrate binding domain Ribosomal_S17e PF00833.13 CBZ49790.1 - 4.8e-59 197.4 1.0 5.4e-59 197.2 0.7 1.0 1 0 0 1 1 1 1 Ribosomal S17 NHL PF01436.16 CBZ49791.1 - 1.2e-11 43.9 0.2 0.0056 16.5 0.0 4.1 3 0 0 3 3 3 3 NHL repeat GCC2_GCC3 PF07699.8 CBZ49791.1 - 4.2e-05 23.0 332.9 0.0022 17.5 4.1 33.2 23 7 8 31 31 31 18 GCC2 and GCC3 SGL PF08450.7 CBZ49791.1 - 0.0066 15.8 0.0 0.11 11.7 0.0 2.2 1 1 1 2 2 2 2 SMP-30/Gluconolaconase/LRE-like region Lactonase PF10282.4 CBZ49791.1 - 0.15 11.1 0.0 0.37 9.8 0.0 1.5 1 1 1 2 2 2 0 Lactonase, 7-bladed beta-propeller LBR_tudor PF09465.5 CBZ49791.1 - 0.61 9.7 0.0 1.3 8.7 0.0 1.4 1 0 0 1 1 1 0 Lamin-B receptor of TUDOR domain Arylesterase PF01731.15 CBZ49791.1 - 3.2 7.8 0.0 7.6 6.6 0.0 1.5 1 0 0 1 1 1 0 Arylesterase DUF240 PF03086.9 CBZ49791.1 - 8.9 5.9 0.0 16 5.1 0.0 1.2 1 0 0 1 1 1 0 MG032/MG096/MG288 family 2 GCC2_GCC3 PF07699.8 CBZ49792.1 - 4.4e-17 61.3 125.6 2.1e-05 23.9 2.0 14.8 8 4 6 14 14 14 10 GCC2 and GCC3 TFIIB PF00382.14 CBZ49794.1 - 2.2e-23 81.8 0.5 1.7e-10 40.5 0.1 2.5 2 0 0 2 2 2 2 Transcription factor TFIIB repeat BRF1 PF07741.8 CBZ49794.1 - 1.8e-09 37.6 6.5 1.5e-06 28.3 0.6 3.1 2 1 1 3 3 3 2 Brf1-like TBP-binding domain TF_Zn_Ribbon PF08271.7 CBZ49794.1 - 2.2e-07 30.0 1.5 4.4e-07 29.1 1.1 1.5 1 0 0 1 1 1 1 TFIIB zinc-binding HTH_Crp_2 PF13545.1 CBZ49794.1 - 0.013 15.2 0.9 0.024 14.4 0.0 1.9 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain HTH_24 PF13412.1 CBZ49794.1 - 0.026 13.8 0.1 0.2 11.1 0.0 2.4 3 0 0 3 3 3 0 Winged helix-turn-helix DNA-binding Na_Ca_ex PF01699.19 CBZ49795.1 - 4.6e-39 133.2 30.1 5.3e-21 74.6 8.5 2.3 2 0 0 2 2 2 2 Sodium/calcium exchanger protein DUF3366 PF11846.3 CBZ49795.1 - 0.32 10.8 4.4 1.7 8.4 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3366) DUF4191 PF13829.1 CBZ49795.1 - 0.86 8.6 0.0 0.86 8.6 0.0 3.0 3 1 0 3 3 3 0 Domain of unknown function (DUF4191) DUF3493 PF11998.3 CBZ49795.1 - 8.4 6.3 7.5 3.7 7.5 2.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3493) MIP-T3 PF10243.4 CBZ49796.1 - 0.69 8.3 28.9 1.2 7.4 20.0 1.3 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 PBP PF01161.15 CBZ49797.1 - 4e-16 59.1 0.1 5.1e-16 58.8 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Ribosomal_S9 PF00380.14 CBZ49798.1 - 1.2e-30 106.2 0.0 2.1e-30 105.4 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Prok-RING_4 PF14447.1 CBZ49798.1 - 0.11 12.0 0.2 3.8 7.1 0.0 2.5 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 Epiglycanin_C PF14654.1 CBZ49799.1 - 0.071 13.1 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 Mucin, catalytic, TM and cytoplasmic tail region Phage_Coat_Gp8 PF05371.7 CBZ49799.1 - 0.59 9.7 2.1 0.38 10.3 0.3 1.5 2 0 0 2 2 2 0 Phage major coat protein, Gp8 DUF1712 PF08217.6 CBZ49800.1 - 4.2e-26 91.3 0.0 5.2e-24 84.4 0.0 2.6 3 0 0 3 3 3 2 Fungal domain of unknown function (DUF1712) Daxx PF03344.10 CBZ49800.1 - 1.6 7.1 5.5 2.7 6.3 3.8 1.3 1 0 0 1 1 1 0 Daxx Family DAO PF01266.19 CBZ49801.1 - 1.2e-07 31.0 0.1 2.1e-07 30.1 0.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 CBZ49801.1 - 5.3e-07 28.8 0.1 7.6e-07 28.3 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain FAD_binding_3 PF01494.14 CBZ49801.1 - 3.1e-05 23.1 0.5 0.032 13.2 0.1 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 CBZ49801.1 - 6.1e-05 22.9 0.1 0.00014 21.8 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 CBZ49801.1 - 0.0023 17.8 0.0 0.0048 16.7 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 CBZ49801.1 - 0.0087 14.5 0.1 0.014 13.9 0.1 1.2 1 0 0 1 1 1 1 HI0933-like protein Lycopene_cycl PF05834.7 CBZ49801.1 - 0.0089 14.9 0.2 0.048 12.5 0.0 1.9 2 0 0 2 2 2 1 Lycopene cyclase protein Thi4 PF01946.12 CBZ49801.1 - 0.051 12.6 0.0 0.081 12.0 0.0 1.2 1 0 0 1 1 1 0 Thi4 family NAD_binding_9 PF13454.1 CBZ49801.1 - 0.076 12.7 0.0 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding GIDA PF01134.17 CBZ49801.1 - 0.086 11.6 0.4 0.13 11.1 0.3 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A HEAT_EZ PF13513.1 CBZ49802.1 - 3.2e-05 24.2 13.1 0.29 11.6 0.4 6.1 5 0 0 5 5 5 3 HEAT-like repeat HEAT PF02985.17 CBZ49802.1 - 0.0026 17.6 9.1 0.33 11.1 0.1 5.4 4 0 0 4 4 4 2 HEAT repeat PIG-P PF08510.7 CBZ49803.1 - 8.5e-33 112.6 1.0 1.2e-32 112.1 0.7 1.2 1 0 0 1 1 1 1 PIG-P DUF4131 PF13567.1 CBZ49803.1 - 1.7 7.9 4.6 3 7.2 3.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) Spb1_C PF07780.7 CBZ49804.1 - 1.7e-62 210.7 26.2 1.7e-62 210.7 18.2 4.6 5 2 0 5 5 5 1 Spb1 C-terminal domain FtsJ PF01728.14 CBZ49804.1 - 1.5e-56 191.2 0.2 2.4e-56 190.5 0.1 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase DUF3381 PF11861.3 CBZ49804.1 - 2.6e-20 72.5 4.1 2.6e-20 72.5 2.9 6.0 5 1 0 6 6 6 1 Domain of unknown function (DUF3381) Use1 PF09753.4 CBZ49805.1 - 7.2e-06 25.6 0.0 1.1e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 Membrane fusion protein Use1 AP2 PF00847.15 CBZ49806.1 - 1.4e-12 47.5 6.2 3.3e-08 33.5 0.4 3.1 3 0 0 3 3 3 2 AP2 domain Macoilin PF09726.4 CBZ49806.1 - 8.3 4.5 3.8 43 2.1 0.0 2.5 2 0 0 2 2 2 0 Transmembrane protein PAN_4 PF14295.1 CBZ49807.1 - 1.7e-36 123.6 35.1 1.3e-06 28.0 0.7 6.7 6 0 0 6 6 6 6 PAN domain PAN_1 PF00024.21 CBZ49807.1 - 2.8e-35 119.8 49.7 3e-07 30.1 4.0 6.3 3 3 3 6 6 6 6 PAN domain PAN_2 PF08276.6 CBZ49807.1 - 0.00015 21.5 44.9 0.039 13.8 0.1 7.1 6 2 1 7 7 7 5 PAN-like domain PAN_3 PF08277.7 CBZ49807.1 - 0.00021 20.8 27.0 0.32 10.6 0.5 6.6 6 0 0 6 6 6 4 PAN-like domain MANEC PF07502.9 CBZ49807.1 - 0.025 14.5 31.0 1.9 8.5 1.0 6.4 6 0 0 6 6 6 0 MANEC domain Aldo_ket_red PF00248.16 CBZ49808.1 - 4e-58 196.4 0.0 5.9e-58 195.9 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family ABC_tran PF00005.22 CBZ49809.1 - 6.1e-40 136.6 0.0 6.9e-21 74.9 0.0 3.7 2 2 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 CBZ49809.1 - 5.8e-28 98.0 8.0 8.1e-21 74.6 0.1 2.8 3 0 0 3 3 3 2 ABC transporter transmembrane region DUF258 PF03193.11 CBZ49809.1 - 3.3e-07 29.6 0.3 0.00031 19.9 0.1 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_25 PF13481.1 CBZ49809.1 - 2.3e-06 27.1 0.2 0.015 14.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 CBZ49809.1 - 7.7e-06 25.3 0.7 0.025 14.1 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.1 CBZ49809.1 - 4.6e-05 23.5 0.0 0.19 11.6 0.1 3.1 3 0 0 3 3 3 2 AAA domain AAA_23 PF13476.1 CBZ49809.1 - 0.00014 22.3 0.0 0.0089 16.3 0.0 2.2 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 CBZ49809.1 - 0.0068 16.3 0.1 1.7 8.6 0.0 2.3 2 0 0 2 2 2 1 50S ribosome-binding GTPase IstB_IS21 PF01695.12 CBZ49809.1 - 0.012 15.0 0.7 0.28 10.6 0.1 2.5 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_17 PF13207.1 CBZ49809.1 - 0.017 15.9 0.0 8.1 7.2 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 CBZ49809.1 - 0.018 14.5 0.1 0.26 10.6 0.0 2.2 2 0 0 2 2 2 0 AAA-like domain Zeta_toxin PF06414.7 CBZ49809.1 - 0.018 14.1 4.4 0.039 13.0 0.0 2.8 3 0 0 3 3 3 0 Zeta toxin AAA_22 PF13401.1 CBZ49809.1 - 0.022 14.8 0.0 2.2 8.4 0.0 2.9 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 CBZ49809.1 - 0.037 13.6 0.8 0.64 9.6 0.0 2.9 3 0 0 3 3 3 0 NACHT domain Miro PF08477.8 CBZ49809.1 - 0.11 12.9 0.0 26 5.3 0.0 2.4 2 0 0 2 2 2 0 Miro-like protein MobB PF03205.9 CBZ49809.1 - 0.14 11.8 0.5 6.7 6.4 0.0 2.3 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B T2SE PF00437.15 CBZ49809.1 - 0.3 9.9 0.1 1.8 7.3 0.0 2.0 2 0 0 2 2 2 0 Type II/IV secretion system protein Dynamin_N PF00350.18 CBZ49809.1 - 0.3 10.8 2.9 12 5.6 0.3 2.3 2 0 0 2 2 2 0 Dynamin family AAA_18 PF13238.1 CBZ49809.1 - 0.43 10.8 0.0 40 4.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.8 CBZ49809.1 - 0.7 8.7 0.2 8.9 5.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF815) RNA_helicase PF00910.17 CBZ49809.1 - 1.7 8.8 0.1 39 4.4 0.0 2.3 2 0 0 2 2 2 0 RNA helicase Arch_ATPase PF01637.13 CBZ49809.1 - 1.8 8.2 0.0 3.5 7.2 0.0 1.4 1 0 0 1 1 1 0 Archaeal ATPase AAA_15 PF13175.1 CBZ49809.1 - 3.4 6.6 0.0 27 3.6 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain Guanylate_kin PF00625.16 CBZ49809.1 - 5.3 6.4 0.1 9.6 5.5 0.0 1.4 1 0 0 1 1 1 0 Guanylate kinase IPK PF03770.11 CBZ49810.1 - 5.1e-51 173.1 0.0 8.3e-51 172.4 0.0 1.3 1 0 0 1 1 1 1 Inositol polyphosphate kinase 5-FTHF_cyc-lig PF01812.15 CBZ49811.1 - 2e-20 73.3 0.0 1.6e-13 50.8 0.0 2.1 2 0 0 2 2 2 2 5-formyltetrahydrofolate cyclo-ligase family PHD PF00628.24 CBZ49812.1 - 1.3e-10 40.8 14.4 2.4e-10 39.9 10.0 1.5 1 0 0 1 1 1 1 PHD-finger ING PF12998.2 CBZ49812.1 - 3e-06 27.4 0.8 4.1e-06 27.0 0.5 1.1 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD_2 PF13831.1 CBZ49812.1 - 0.014 14.7 7.9 0.025 13.9 5.5 1.5 1 0 0 1 1 1 0 PHD-finger zf-RING_2 PF13639.1 CBZ49812.1 - 0.02 14.7 10.7 0.039 13.7 7.4 1.5 1 0 0 1 1 1 0 Ring finger domain PHF5 PF03660.9 CBZ49812.1 - 0.076 13.0 3.4 0.14 12.2 2.4 1.4 1 0 0 1 1 1 0 PHF5-like protein zf-PHD-like PF15446.1 CBZ49812.1 - 0.17 11.1 5.1 0.27 10.5 3.5 1.3 1 0 0 1 1 1 0 PHD/FYVE-zinc-finger like domain Prok-RING_1 PF14446.1 CBZ49812.1 - 1.4 8.7 11.2 0.44 10.3 4.6 2.1 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 zf-C3HC4_2 PF13923.1 CBZ49812.1 - 5.9 6.9 10.1 12 5.9 7.0 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) FHA PF00498.21 CBZ49813.1 - 3.1e-07 30.3 0.0 6.5e-07 29.3 0.0 1.5 1 0 0 1 1 1 1 FHA domain FlxA PF14282.1 CBZ49813.1 - 0.049 13.5 12.6 0.23 11.4 4.1 2.9 2 0 0 2 2 2 0 FlxA-like protein DUF680 PF05079.7 CBZ49813.1 - 3.9 8.0 7.5 0.43 11.0 1.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF680) PNK3P PF08645.6 CBZ49814.1 - 2.1e-41 140.9 0.0 2.8e-26 91.8 0.0 2.5 2 0 0 2 2 2 2 Polynucleotide kinase 3 phosphatase AAA_33 PF13671.1 CBZ49814.1 - 8.8e-17 61.3 0.4 5.5e-16 58.7 0.3 2.3 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 CBZ49814.1 - 4.6e-06 25.8 0.1 2e-05 23.7 0.0 1.9 1 1 1 2 2 2 1 Zeta toxin AAA_16 PF13191.1 CBZ49814.1 - 0.00057 19.9 0.0 0.0031 17.5 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_17 PF13207.1 CBZ49814.1 - 0.0029 18.3 0.1 0.017 15.9 0.1 2.3 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.1 CBZ49814.1 - 0.006 16.7 0.2 0.029 14.5 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 CBZ49814.1 - 0.016 15.4 0.4 0.054 13.8 0.3 1.9 1 1 0 1 1 1 0 AAA domain NB-ARC PF00931.17 CBZ49814.1 - 0.024 13.5 0.0 0.043 12.6 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_29 PF13555.1 CBZ49814.1 - 0.033 13.7 0.1 0.083 12.4 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.22 CBZ49814.1 - 0.04 14.2 0.0 0.074 13.3 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA_14 PF13173.1 CBZ49814.1 - 0.092 12.6 0.0 0.2 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 CBZ49814.1 - 0.1 12.3 0.0 0.24 11.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_10 PF12846.2 CBZ49814.1 - 0.1 12.0 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain AAA_25 PF13481.1 CBZ49814.1 - 0.11 11.9 0.0 0.36 10.2 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 CBZ49814.1 - 0.11 12.4 0.3 0.37 10.7 0.2 1.9 1 0 0 1 1 1 0 AAA domain KTI12 PF08433.5 CBZ49814.1 - 0.16 11.1 4.6 0.5 9.5 0.1 2.2 1 1 1 2 2 2 0 Chromatin associated protein KTI12 MMR_HSR1 PF01926.18 CBZ49814.1 - 0.17 11.8 0.0 0.44 10.5 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_24 PF13479.1 CBZ49814.1 - 0.17 11.4 0.0 0.31 10.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain Reo_sigmaC PF04582.7 CBZ49815.1 - 7 5.7 15.8 0.24 10.5 1.1 3.1 1 1 1 3 3 3 0 Reovirus sigma C capsid protein RRM_1 PF00076.17 CBZ49816.1 - 7e-05 22.3 0.0 0.00013 21.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBZ49816.1 - 0.0088 16.0 0.0 0.015 15.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Btz PF09405.5 CBZ49816.1 - 0.04 13.9 5.3 0.094 12.7 0.3 3.0 1 1 1 2 2 2 0 CASC3/Barentsz eIF4AIII binding F-actin_cap_A PF01267.12 CBZ49819.1 - 1.6e-18 66.7 0.0 1.5e-12 47.1 0.0 2.1 2 0 0 2 2 2 2 F-actin capping protein alpha subunit SNF PF00209.13 CBZ49821.1 - 2.6e-23 82.3 21.9 2.6e-23 82.3 15.2 1.7 2 0 0 2 2 2 1 Sodium:neurotransmitter symporter family SNF PF00209.13 CBZ49822.1 - 8.2e-26 90.5 33.1 8.2e-26 90.5 22.9 1.9 2 0 0 2 2 2 1 Sodium:neurotransmitter symporter family Kazal_1 PF00050.16 CBZ49823.1 - 2.4e-19 69.0 45.3 1.5e-06 28.1 4.7 4.6 3 1 1 4 4 4 4 Kazal-type serine protease inhibitor domain Kazal_2 PF07648.10 CBZ49823.1 - 3.3e-09 36.5 39.4 6.7e-05 22.7 4.4 4.9 4 0 0 4 4 4 3 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.16 CBZ49825.1 - 1.2e-17 63.6 29.1 1.6e-06 28.0 1.9 4.6 4 1 0 4 4 4 3 Kazal-type serine protease inhibitor domain Kazal_2 PF07648.10 CBZ49825.1 - 8e-07 28.8 25.5 0.0024 17.7 1.4 4.3 4 0 0 4 4 4 3 Kazal-type serine protease inhibitor domain DUF3012 PF11216.3 CBZ49825.1 - 0.4 10.3 2.7 6.3 6.5 0.1 3.0 4 0 0 4 4 4 0 Protein of unknown function (DUF3012) MMR_HSR1 PF01926.18 CBZ49826.1 - 2.3e-16 59.8 0.1 2.4e-14 53.2 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 CBZ49826.1 - 3.7e-06 26.2 0.0 0.00012 21.3 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B TFIIA PF03153.8 CBZ49826.1 - 3.3e-05 23.9 12.9 3.3e-05 23.9 9.0 2.4 2 0 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit DUF258 PF03193.11 CBZ49826.1 - 0.0071 15.5 0.0 0.016 14.3 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Miro PF08477.8 CBZ49826.1 - 0.089 13.2 0.1 0.41 11.1 0.0 2.1 2 0 0 2 2 2 0 Miro-like protein Nop14 PF04147.7 CBZ49826.1 - 0.56 8.0 52.9 0.027 12.4 27.6 2.4 2 0 0 2 2 2 0 Nop14-like family PP2C PF00481.16 CBZ49827.1 - 4.4e-55 186.8 0.0 8.9e-51 172.7 0.0 2.3 1 1 0 2 2 2 2 Protein phosphatase 2C NAPRTase PF04095.11 CBZ49830.1 - 8.1e-19 67.8 0.0 3.5e-09 36.2 0.0 2.2 2 0 0 2 2 2 2 Nicotinate phosphoribosyltransferase (NAPRTase) family QRPTase_N PF02749.11 CBZ49830.1 - 0.09 12.6 0.0 0.33 10.8 0.0 2.0 1 1 0 1 1 1 0 Quinolinate phosphoribosyl transferase, N-terminal domain DEAD PF00270.24 CBZ49831.1 - 2e-36 125.0 0.4 8.2e-36 123.0 0.0 2.3 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CBZ49831.1 - 1.1e-21 76.4 0.0 2.4e-21 75.3 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 CBZ49831.1 - 0.00034 19.5 0.0 0.00083 18.2 0.0 1.6 1 0 0 1 1 1 1 SNF2 family N-terminal domain DBP10CT PF08147.7 CBZ49831.1 - 0.0012 18.5 5.4 0.0012 18.5 3.7 2.6 2 0 0 2 2 2 1 DBP10CT (NUC160) domain ResIII PF04851.10 CBZ49831.1 - 0.0028 17.4 0.3 0.009 15.8 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DsrH PF04077.7 CBZ49831.1 - 0.086 12.5 0.0 0.23 11.1 0.0 1.7 1 0 0 1 1 1 0 DsrH like protein Xpo1 PF08389.7 CBZ49832.1 - 0.067 13.1 0.1 0.14 12.0 0.1 1.6 1 1 0 1 1 1 0 Exportin 1-like protein Calici_PP_N PF08405.6 CBZ49832.1 - 0.14 11.0 0.7 4.3 6.0 0.0 2.0 1 1 1 2 2 2 0 Viral polyprotein N-terminal Mito_carr PF00153.22 CBZ49833.1 - 4.9e-15 55.0 0.1 2.1e-05 24.1 0.0 4.4 4 1 0 4 4 4 3 Mitochondrial carrier protein Retinal PF15449.1 CBZ49833.1 - 0.034 11.8 0.8 0.044 11.4 0.5 1.1 1 0 0 1 1 1 0 Retinal protein UQ_con PF00179.21 CBZ49834.1 - 0.00083 18.8 0.0 0.0017 17.7 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme DNA_ligase_A_M PF01068.16 CBZ49835.1 - 7.3e-41 139.7 1.1 1.4e-31 109.4 0.3 2.6 2 1 0 2 2 2 2 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 CBZ49835.1 - 2e-39 135.2 0.1 3.6e-39 134.3 0.0 1.4 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 CBZ49835.1 - 4.5e-22 78.2 0.0 1.2e-21 76.9 0.0 1.8 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region mRNA_cap_enzyme PF01331.14 CBZ49835.1 - 0.067 12.8 0.1 0.22 11.1 0.1 1.8 1 1 0 1 1 1 0 mRNA capping enzyme, catalytic domain V-ATPase_H_C PF11698.3 CBZ49836.1 - 2.6e-48 162.8 0.9 1e-47 160.9 0.5 2.1 2 0 0 2 2 2 1 V-ATPase subunit H V-ATPase_H_N PF03224.9 CBZ49836.1 - 3.1e-38 131.6 0.0 5.2e-38 130.9 0.0 1.3 1 0 0 1 1 1 1 V-ATPase subunit H Arm_2 PF04826.8 CBZ49836.1 - 0.064 12.3 0.1 0.36 9.8 0.0 2.0 1 1 1 2 2 2 0 Armadillo-like Endonuclease_NS PF01223.18 CBZ49837.1 - 1.1e-28 100.3 0.0 1.7e-20 73.5 0.0 2.3 2 0 0 2 2 2 2 DNA/RNA non-specific endonuclease Endonuclea_NS_2 PF13930.1 CBZ49837.1 - 0.22 11.5 0.0 0.57 10.2 0.0 1.6 1 0 0 1 1 1 0 DNA/RNA non-specific endonuclease DSPc PF00782.15 CBZ49838.1 - 1.4e-07 31.1 0.0 2e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 CBZ49838.1 - 1.1e-06 28.2 0.0 1.8e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 CBZ49838.1 - 0.00048 20.1 0.0 0.001 19.1 0.0 1.5 1 0 0 1 1 1 1 Inositol hexakisphosphate MAR_sialic_bdg PF10564.4 CBZ49839.1 - 6.7e-35 118.8 28.3 5.9e-19 67.6 1.7 4.6 4 1 1 5 5 5 4 Sialic-acid binding micronemal adhesive repeat MAR_sialic_bdg PF10564.4 CBZ49840.1 - 4.8e-43 144.9 30.9 7.9e-20 70.4 5.5 4.3 3 1 1 4 4 4 4 Sialic-acid binding micronemal adhesive repeat DUF234 PF03008.9 CBZ49840.1 - 0.049 13.7 0.0 0.1 12.7 0.0 1.5 1 0 0 1 1 1 0 Archaea bacterial proteins of unknown function RWD PF05773.17 CBZ49841.1 - 2.1e-14 53.3 0.3 3.5e-14 52.6 0.2 1.3 1 0 0 1 1 1 1 RWD domain DUF688 PF05097.7 CBZ49841.1 - 0.68 8.8 6.1 0.087 11.7 1.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF688) Voldacs PF03517.8 CBZ49841.1 - 1 9.2 6.2 0.53 10.1 0.3 2.3 2 0 0 2 2 2 0 Regulator of volume decrease after cellular swelling cEGF PF12662.2 CBZ49842.1 - 0.15 11.7 4.7 8.4 6.1 0.4 3.5 3 0 0 3 3 3 0 Complement Clr-like EGF-like UQ_con PF00179.21 CBZ49844.1 - 4e-44 149.4 0.0 5.1e-44 149.1 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 CBZ49844.1 - 0.041 13.7 0.0 0.068 13.0 0.0 1.5 1 1 0 1 1 1 0 RWD domain Prok-E2_B PF14461.1 CBZ49844.1 - 0.062 13.0 0.0 0.097 12.4 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic E2 family B Mito_carr PF00153.22 CBZ49845.1 - 8.3e-18 63.8 3.5 2e-07 30.6 0.1 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF1203 PF06718.6 CBZ49846.1 - 0.019 14.7 0.0 0.055 13.2 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1203) TPR_11 PF13414.1 CBZ49847.1 - 1.2e-14 53.6 13.1 1.4e-08 34.2 0.9 2.5 1 1 2 3 3 3 3 TPR repeat TPR_19 PF14559.1 CBZ49847.1 - 1.8e-10 40.9 1.7 7.1e-06 26.2 0.0 2.8 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.23 CBZ49847.1 - 1e-09 37.6 3.5 4e-05 23.0 0.4 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 CBZ49847.1 - 1.1e-09 37.3 5.0 0.0086 15.9 0.2 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.1 CBZ49847.1 - 1.9e-09 37.3 4.1 7e-06 25.8 0.5 2.6 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.1 CBZ49847.1 - 1.1e-08 35.5 1.7 1.4e-07 31.9 0.5 3.1 3 1 0 3 3 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 CBZ49847.1 - 2.7e-07 30.6 2.6 0.005 17.3 0.0 3.6 3 1 1 4 4 2 2 Tetratricopeptide repeat TPR_7 PF13176.1 CBZ49847.1 - 2.6e-06 26.7 0.6 0.0049 16.5 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 CBZ49847.1 - 0.0001 21.8 2.1 0.0083 15.8 0.1 3.2 2 1 1 3 3 3 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 CBZ49847.1 - 0.00015 21.5 2.4 0.35 10.7 0.0 2.7 2 1 1 3 3 3 2 Fis1 C-terminal tetratricopeptide repeat TPR_6 PF13174.1 CBZ49847.1 - 0.00019 21.6 1.7 0.0068 16.7 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.1 CBZ49847.1 - 0.0021 18.1 0.5 48 4.5 0.0 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat Sec16_C PF12931.2 CBZ49847.1 - 0.004 16.9 0.0 0.007 16.1 0.0 1.3 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 TPR_10 PF13374.1 CBZ49847.1 - 0.2 11.6 3.2 4.4 7.3 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat DXP_synthase_N PF13292.1 CBZ49848.1 - 4e-88 294.8 0.0 6.6e-75 251.5 0.0 2.8 3 0 0 3 3 3 2 1-deoxy-D-xylulose-5-phosphate synthase Transket_pyr PF02779.19 CBZ49848.1 - 2.3e-41 141.2 0.0 5.1e-41 140.1 0.0 1.5 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 CBZ49848.1 - 7.2e-20 71.1 0.0 1.7e-17 63.5 0.0 2.9 2 0 0 2 2 2 1 Transketolase, C-terminal domain Transketolase_N PF00456.16 CBZ49848.1 - 9e-08 31.2 0.0 0.0088 14.8 0.0 2.4 3 0 0 3 3 3 2 Transketolase, thiamine diphosphate binding domain E1_dh PF00676.15 CBZ49848.1 - 0.02 13.5 0.1 0.046 12.4 0.0 1.5 2 0 0 2 2 2 0 Dehydrogenase E1 component DEAD PF00270.24 CBZ49850.1 - 2.1e-19 69.6 0.0 7.1e-17 61.4 0.0 2.6 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.26 CBZ49850.1 - 1.6e-14 53.5 0.2 4.3e-14 52.1 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 CBZ49850.1 - 7.5e-07 29.1 0.0 1.3e-05 25.1 0.0 2.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.1 CBZ49850.1 - 0.00054 19.6 0.1 0.0016 18.1 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain SecA_DEAD PF07517.9 CBZ49850.1 - 0.021 14.1 0.0 0.042 13.1 0.0 1.4 1 0 0 1 1 1 0 SecA DEAD-like domain Zot PF05707.7 CBZ49850.1 - 0.099 12.1 0.0 0.2 11.0 0.0 1.5 1 0 0 1 1 1 0 Zonular occludens toxin (Zot) UPF0079 PF02367.12 CBZ49850.1 - 0.12 11.9 0.0 0.28 10.8 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 RC-P840_PscD PF10657.4 CBZ49850.1 - 0.31 10.9 0.0 0.58 10.0 0.0 1.3 1 0 0 1 1 1 0 Photosystem P840 reaction centre protein PscD SAG PF04092.8 CBZ49851.1 - 9.9e-15 55.0 7.4 1.2e-14 54.7 5.1 1.1 1 0 0 1 1 1 1 SRS domain RRM_1 PF00076.17 CBZ49853.1 - 4e-12 45.5 0.0 2.5e-06 27.0 0.0 2.3 1 1 1 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBZ49853.1 - 8.5e-12 44.8 0.0 3.8e-11 42.7 0.0 2.0 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBZ49853.1 - 1.1e-06 28.3 0.0 2.7e-06 27.1 0.0 1.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) G-patch_2 PF12656.2 CBZ49855.1 - 3.4e-17 62.0 0.7 9.5e-17 60.6 0.5 1.8 1 0 0 1 1 1 1 DExH-box splicing factor binding site HECT PF00632.20 CBZ49856.1 - 3.7e-46 157.7 0.0 6e-46 157.0 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Ank_5 PF13857.1 CBZ49856.1 - 5.8e-11 42.2 1.1 2.5e-05 24.3 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 CBZ49856.1 - 3.1e-10 40.2 0.0 8e-08 32.5 0.0 2.9 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.25 CBZ49856.1 - 5.7e-10 38.4 0.0 0.0018 18.0 0.0 4.7 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.1 CBZ49856.1 - 4.7e-07 30.1 0.0 0.043 14.3 0.0 4.2 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 CBZ49856.1 - 0.12 12.6 0.0 37 4.9 0.0 4.1 4 0 0 4 4 4 0 Ankyrin repeat SF-assemblin PF06705.6 CBZ49856.1 - 7.8 5.5 2.0 13 4.7 1.4 1.2 1 0 0 1 1 1 0 SF-assemblin/beta giardin Rad52_Rad22 PF04098.10 CBZ49856.1 - 9.2 5.9 0.0 18 4.9 0.0 1.4 1 0 0 1 1 1 0 Rad52/22 family double-strand break repair protein EF_TS PF00889.14 CBZ49857.1 - 8.7e-26 90.6 0.0 4.4e-15 55.6 0.0 2.6 2 1 0 2 2 2 2 Elongation factor TS UBA PF00627.26 CBZ49857.1 - 0.00045 19.9 0.4 0.0016 18.2 0.1 2.1 2 0 0 2 2 2 1 UBA/TS-N domain UBA_4 PF14555.1 CBZ49857.1 - 0.063 12.8 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 UBA-like domain Pedibin PF08182.6 CBZ49858.1 - 0.13 11.7 1.8 9.5 5.8 0.1 2.4 1 1 1 2 2 2 0 Pedibin/Hym-346 family Actin PF00022.14 CBZ49859.1 - 1.1e-154 514.5 0.0 1.3e-154 514.4 0.0 1.0 1 0 0 1 1 1 1 Actin ESSS PF10183.4 CBZ49859.1 - 0.11 12.8 0.0 0.34 11.3 0.0 1.8 1 1 1 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) DUF4201 PF13870.1 CBZ49860.1 - 6.2e-28 97.4 37.9 1.3e-27 96.4 16.9 3.0 3 0 0 3 3 3 2 Domain of unknown function (DUF4201) Ank_5 PF13857.1 CBZ49860.1 - 9.2e-07 28.9 0.0 2.2e-06 27.7 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.25 CBZ49860.1 - 3.5e-05 23.3 0.1 7.6e-05 22.3 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeat Ank_3 PF13606.1 CBZ49860.1 - 0.0039 17.2 0.0 0.01 16.0 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeat LPP PF04728.8 CBZ49860.1 - 0.017 14.9 1.6 0.11 12.2 0.0 2.8 3 0 0 3 3 3 0 Lipoprotein leucine-zipper Ank_2 PF12796.2 CBZ49860.1 - 0.062 13.6 0.0 0.16 12.3 0.0 1.7 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) Cep57_CLD_2 PF14197.1 CBZ49860.1 - 0.1 12.5 0.2 0.1 12.5 0.1 5.0 3 2 1 4 4 4 0 Centrosome localisation domain of PPC89 EFP PF01132.15 CBZ49860.1 - 0.11 12.2 3.3 1.4 8.6 0.1 2.7 2 0 0 2 2 2 0 Elongation factor P (EF-P) OB domain bZIP_1 PF00170.16 CBZ49860.1 - 2.5 8.1 22.6 2 8.4 2.6 4.8 3 1 2 5 5 5 0 bZIP transcription factor APG6 PF04111.7 CBZ49860.1 - 6.2 5.7 39.4 0.27 10.2 7.7 3.2 1 1 1 3 3 3 0 Autophagy protein Apg6 Pkinase PF00069.20 CBZ49861.1 - 6.2e-50 169.7 0.0 8.6e-50 169.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ49861.1 - 4.3e-41 140.6 0.0 5.8e-41 140.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CBZ49861.1 - 0.0092 15.7 0.0 0.086 12.5 0.1 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.1 CBZ49861.1 - 0.024 13.6 0.0 0.039 12.9 0.0 1.3 1 0 0 1 1 1 0 Kinase-like TSP_1 PF00090.14 CBZ49862.1 - 1.4e-23 82.7 66.7 4.5e-09 36.2 4.3 7.8 7 0 0 7 7 7 5 Thrombospondin type 1 domain PAN_1 PF00024.21 CBZ49862.1 - 6.2e-05 22.6 7.1 0.0064 16.2 0.1 3.4 3 0 0 3 3 3 2 PAN domain PAN_4 PF14295.1 CBZ49862.1 - 0.0014 18.2 0.2 0.0014 18.2 0.1 5.0 5 1 0 5 5 5 2 PAN domain TRAPP PF04051.11 CBZ49864.1 - 2.2e-39 134.4 0.0 7.3e-39 132.7 0.0 1.7 1 1 0 1 1 1 1 Transport protein particle (TRAPP) component VIT PF08487.5 CBZ49864.1 - 0.13 11.9 0.1 3.9 7.1 0.2 2.2 1 1 1 2 2 2 0 Vault protein inter-alpha-trypsin domain DUF3682 PF12446.3 CBZ49864.1 - 1.4 9.2 8.1 6.6 7.0 0.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3682) UMP1 PF05348.6 CBZ49865.1 - 4.6e-15 55.7 0.0 5.6e-15 55.4 0.0 1.1 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 PUB PF09409.5 CBZ49866.1 - 4.2e-15 55.2 0.0 4.5e-14 51.9 0.0 2.2 2 0 0 2 2 2 1 PUB domain UBX PF00789.15 CBZ49866.1 - 0.012 15.6 0.2 0.036 14.1 0.1 1.8 1 1 0 1 1 1 0 UBX domain Selenoprotein_S PF06936.6 CBZ49866.1 - 0.17 11.4 4.5 0.34 10.4 2.5 2.0 2 0 0 2 2 2 0 Selenoprotein S (SelS) bZIP_C PF12498.3 CBZ49866.1 - 6.4 8.0 10.5 0.57 11.4 0.9 2.9 3 0 0 3 3 3 0 Basic leucine-zipper C terminal DCP1 PF06058.8 CBZ49867.1 - 4.7e-23 81.5 0.1 9.1e-23 80.6 0.1 1.4 1 1 0 1 1 1 1 Dcp1-like decapping family UPF0139 PF03669.8 CBZ49868.1 - 1.3e-05 24.6 0.0 1.6e-05 24.3 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0139) RCC1 PF00415.13 CBZ49869.1 - 8.3e-63 208.4 25.0 6.8e-14 51.8 0.2 8.3 7 1 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 CBZ49869.1 - 1.7e-19 68.9 42.9 1.6e-05 24.3 0.3 6.7 6 0 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat Kelch_2 PF07646.10 CBZ49869.1 - 0.022 14.4 0.3 0.33 10.8 0.1 2.9 3 0 0 3 3 3 0 Kelch motif FlxA PF14282.1 CBZ49869.1 - 0.046 13.6 3.1 0.086 12.7 2.2 1.3 1 0 0 1 1 1 0 FlxA-like protein Tropomyosin_1 PF12718.2 CBZ49869.1 - 0.17 11.7 2.0 0.35 10.7 1.4 1.4 1 0 0 1 1 1 0 Tropomyosin like Kelch_4 PF13418.1 CBZ49869.1 - 0.37 10.5 6.4 1.3 8.8 0.7 4.2 5 0 0 5 5 5 0 Galactose oxidase, central domain TPR_MLP1_2 PF07926.7 CBZ49869.1 - 0.71 9.6 5.8 1.1 9.0 4.0 1.2 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein ASF1_hist_chap PF04729.8 CBZ49870.1 - 9.7e-34 116.2 0.0 1.2e-33 115.9 0.0 1.1 1 0 0 1 1 1 1 ASF1 like histone chaperone Pyr_redox_2 PF07992.9 CBZ49871.1 - 7.7e-23 81.4 0.0 1.5e-21 77.2 0.0 3.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 CBZ49871.1 - 1e-10 41.8 0.0 1.8e-09 37.8 0.0 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DNAPolymera_Pol PF11590.3 CBZ49871.1 - 0.00042 19.9 0.1 0.0013 18.3 0.1 1.9 1 0 0 1 1 1 1 DNA polymerase catalytic subunit Pol Pyr_redox_3 PF13738.1 CBZ49871.1 - 0.011 15.7 0.9 2.9 7.8 0.2 3.6 3 1 1 4 4 4 0 Pyridine nucleotide-disulphide oxidoreductase NMT_C PF02799.10 CBZ49872.1 - 1.2e-79 266.1 0.0 3e-79 264.8 0.0 1.6 2 0 0 2 2 2 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain NMT PF01233.14 CBZ49872.1 - 3.9e-74 247.6 0.1 7.4e-74 246.7 0.1 1.5 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain Acetyltransf_9 PF13527.1 CBZ49872.1 - 1.7e-06 27.8 0.0 1.6e-05 24.7 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 CBZ49872.1 - 0.043 13.9 0.0 0.11 12.6 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 CBZ49872.1 - 0.074 13.2 0.0 6.8 6.8 0.0 2.4 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 CBZ49872.1 - 0.087 12.8 0.0 0.61 10.1 0.0 2.2 2 0 0 2 2 2 0 Acetyltransferase (GNAT) family PAN_1 PF00024.21 CBZ49874.1 - 1.7e-19 69.3 38.4 1.5e-06 27.8 4.3 5.4 2 2 4 6 6 6 4 PAN domain PAN_4 PF14295.1 CBZ49874.1 - 1.4e-15 56.7 35.3 0.00013 21.5 1.1 5.6 4 1 1 5 5 5 4 PAN domain ABC_membrane PF00664.18 CBZ49875.1 - 2.5e-28 99.3 2.2 6.1e-28 98.0 1.5 1.6 1 1 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.22 CBZ49875.1 - 3.2e-28 98.7 0.0 6e-28 97.8 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 CBZ49875.1 - 1.8e-07 31.4 0.1 0.015 15.2 0.0 2.1 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 CBZ49875.1 - 4.3e-05 23.6 0.5 0.0072 16.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 CBZ49875.1 - 0.00013 21.4 0.3 0.00035 20.0 0.2 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.1 CBZ49875.1 - 0.00066 19.7 3.9 0.0016 18.4 0.0 3.0 3 0 0 3 3 3 1 AAA ATPase domain AAA_17 PF13207.1 CBZ49875.1 - 0.0011 19.7 0.4 0.0039 17.9 0.1 2.1 2 0 0 2 2 1 1 AAA domain SMC_N PF02463.14 CBZ49875.1 - 0.0013 17.9 0.4 0.65 9.1 0.0 2.3 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_25 PF13481.1 CBZ49875.1 - 0.0014 18.0 1.5 0.0026 17.1 0.1 2.1 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 CBZ49875.1 - 0.0026 18.0 0.1 0.0074 16.5 0.1 1.7 1 0 0 1 1 1 1 AAA domain DUF258 PF03193.11 CBZ49875.1 - 0.0029 16.8 0.1 0.0062 15.7 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_10 PF12846.2 CBZ49875.1 - 0.0053 16.2 1.7 0.016 14.6 0.1 2.2 2 0 0 2 2 2 1 AAA-like domain AAA_23 PF13476.1 CBZ49875.1 - 0.011 16.0 0.3 0.011 16.0 0.2 1.6 2 0 0 2 2 1 0 AAA domain AAA_14 PF13173.1 CBZ49875.1 - 0.016 15.0 0.0 0.042 13.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 CBZ49875.1 - 0.018 14.5 0.2 0.053 12.9 0.0 1.8 2 0 0 2 2 2 0 Sigma-54 interaction domain APS_kinase PF01583.15 CBZ49875.1 - 0.018 14.6 0.2 0.058 13.0 0.1 1.9 2 0 0 2 2 2 0 Adenylylsulphate kinase MobB PF03205.9 CBZ49875.1 - 0.029 14.0 0.3 0.7 9.5 0.1 2.3 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B ABC_ATPase PF09818.4 CBZ49875.1 - 0.035 12.6 0.9 0.22 10.0 0.2 2.1 2 0 0 2 2 2 0 Predicted ATPase of the ABC class SbcCD_C PF13558.1 CBZ49875.1 - 0.046 13.6 0.0 0.14 12.1 0.0 1.9 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit DUF87 PF01935.12 CBZ49875.1 - 0.056 13.2 1.2 0.099 12.4 0.2 1.8 2 0 0 2 2 2 0 Domain of unknown function DUF87 AAA_28 PF13521.1 CBZ49875.1 - 0.085 12.8 0.3 0.085 12.8 0.2 2.6 3 0 0 3 3 3 0 AAA domain NACHT PF05729.7 CBZ49875.1 - 0.099 12.2 0.9 0.22 11.1 0.1 2.1 2 0 0 2 2 1 0 NACHT domain AAA_15 PF13175.1 CBZ49875.1 - 0.18 10.8 0.0 0.71 8.8 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain RNA_helicase PF00910.17 CBZ49875.1 - 0.27 11.4 0.1 0.86 9.8 0.0 1.9 2 0 0 2 2 1 0 RNA helicase AAA_33 PF13671.1 CBZ49875.1 - 0.65 9.8 3.0 0.76 9.6 0.0 2.4 3 0 0 3 3 3 0 AAA domain p25-alpha PF05517.7 CBZ49876.1 - 0.073 13.3 0.0 0.53 10.5 0.0 2.2 2 0 0 2 2 2 0 p25-alpha KH_1 PF00013.24 CBZ49877.1 - 1.2e-18 66.4 0.0 7.5e-08 31.9 0.0 4.0 4 0 0 4 4 4 3 KH domain KH_3 PF13014.1 CBZ49877.1 - 1.9e-08 33.7 0.1 0.018 14.7 0.0 4.4 4 0 0 4 4 4 3 KH domain KH_2 PF07650.12 CBZ49877.1 - 0.0026 17.2 0.0 0.079 12.5 0.1 2.9 3 0 0 3 3 3 1 KH domain KH_4 PF13083.1 CBZ49877.1 - 0.1 12.2 0.0 0.56 9.8 0.1 2.2 2 0 0 2 2 2 0 KH domain Methyltrans_RNA PF04452.9 CBZ49878.1 - 8.3e-40 136.2 0.0 1.1e-21 77.0 0.0 2.1 2 0 0 2 2 2 2 RNA methyltransferase DUF2667 PF10868.3 CBZ49878.1 - 0.16 12.3 0.1 0.16 12.3 0.0 2.8 3 1 1 4 4 4 0 Protein of unknown function (DUF2667) PAM2 PF07145.10 CBZ49879.1 - 0.0007 18.9 0.5 0.0024 17.2 0.3 1.9 1 0 0 1 1 1 1 Ataxin-2 C-terminal region P12 PF12669.2 CBZ49879.1 - 0.0024 18.0 0.1 0.0078 16.3 0.1 1.8 1 0 0 1 1 1 1 Virus attachment protein p12 family COX5B PF01215.14 CBZ49880.1 - 1.4e-11 44.2 0.0 2.5e-11 43.4 0.0 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb Ribosomal_S28e PF01200.13 CBZ49883.1 - 8.8e-32 108.6 2.0 9.5e-32 108.5 1.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e WD40 PF00400.27 CBZ49884.1 - 3.1e-21 74.3 12.8 6.4e-08 32.1 0.1 5.9 6 0 0 6 6 6 5 WD domain, G-beta repeat Ribosomal_S4 PF00163.14 CBZ49886.1 - 3.4e-09 36.9 3.2 4.1e-09 36.7 1.7 1.6 1 1 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.20 CBZ49886.1 - 3.7e-09 35.8 0.0 7.7e-09 34.8 0.0 1.5 1 0 0 1 1 1 1 S4 domain DUF2681 PF10883.3 CBZ49889.1 - 0.12 12.5 0.8 0.42 10.8 0.5 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) TLD PF07534.11 CBZ49890.1 - 4.8e-30 104.3 0.1 2.4e-28 98.8 0.0 2.4 2 0 0 2 2 2 1 TLD Cation_ATPase_N PF00690.21 CBZ49890.1 - 0.0013 18.1 0.0 0.0041 16.5 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus DUF399 PF04187.8 CBZ49893.1 - 0.24 10.8 1.8 0.63 9.4 1.3 1.7 1 1 0 1 1 1 0 Protein of unknown function, DUF399 WD40 PF00400.27 CBZ49897.1 - 1.4e-15 56.5 9.8 2e-05 24.3 0.3 5.4 5 0 0 5 5 5 4 WD domain, G-beta repeat PEN-2 PF10251.4 CBZ49898.1 - 8.4e-05 22.7 0.2 0.00013 22.0 0.1 1.3 1 0 0 1 1 1 1 Presenilin enhancer-2 subunit of gamma secretase DDHD PF02862.12 CBZ49898.1 - 0.11 12.2 24.8 0.051 13.3 13.6 2.0 2 0 0 2 2 2 0 DDHD domain FAST_1 PF06743.10 CBZ49900.1 - 0.0061 16.2 7.8 0.33 10.6 0.1 5.4 4 1 2 6 6 6 2 FAST kinase-like protein, subdomain 1 RNase_T PF00929.19 CBZ49902.1 - 4.8e-16 59.4 0.0 6.9e-16 58.9 0.0 1.2 1 0 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.15 CBZ49902.1 - 0.00019 20.9 0.0 0.00037 20.0 0.0 1.4 1 0 0 1 1 1 1 3'-5' exonuclease DUF4554 PF15091.1 CBZ49902.1 - 0.15 10.7 0.1 0.2 10.3 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4554) SLD3 PF08639.5 CBZ49903.1 - 3.1 6.3 5.1 4.8 5.7 3.6 1.3 1 0 0 1 1 1 0 DNA replication regulator SLD3 Bd3614_N PF14442.1 CBZ49905.1 - 2.7 7.9 5.9 2 8.4 2.5 1.8 2 0 0 2 2 2 0 Bd3614-like deaminase N-terminal Asp PF00026.18 CBZ49907.1 - 1.2e-58 198.8 0.0 1.6e-58 198.4 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 CBZ49907.1 - 1e-05 25.5 0.2 2.4e-05 24.3 0.2 1.6 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 CBZ49907.1 - 0.03 14.8 0.3 32 5.1 0.0 3.5 2 2 1 3 3 3 0 Aspartyl protease BioT2 PF15368.1 CBZ49909.1 - 0.051 13.3 0.1 0.12 12.1 0.0 1.6 1 0 0 1 1 1 0 Spermatogenesis family BioT2 DNA_pol_viral_N PF00242.12 CBZ49909.1 - 0.82 8.6 0.0 0.82 8.6 0.0 2.4 3 0 0 3 3 3 0 DNA polymerase (viral) N-terminal domain Telomerase_RBD PF12009.3 CBZ49910.1 - 1.7e-24 86.2 0.0 1.1e-11 44.7 0.0 2.5 2 0 0 2 2 2 2 Telomerase ribonucleoprotein complex - RNA binding domain RVT_1 PF00078.22 CBZ49910.1 - 0.3 10.3 0.0 8.3 5.6 0.0 2.4 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) Ycf1 PF05758.7 CBZ49910.1 - 7.6 4.1 3.6 22 2.5 2.5 1.7 1 0 0 1 1 1 0 Ycf1 Pex14_N PF04695.8 CBZ49911.1 - 0.01 15.8 3.1 0.18 11.8 0.1 2.8 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region RRM_1 PF00076.17 CBZ49912.1 - 6.4e-23 80.1 0.0 2.4e-10 39.8 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBZ49912.1 - 4.2e-18 64.9 0.0 3.2e-12 46.1 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBZ49912.1 - 2e-13 50.0 0.0 4.8e-06 26.4 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Calcipressin PF04847.7 CBZ49912.1 - 0.034 13.7 0.0 0.07 12.6 0.0 1.6 2 0 0 2 2 2 0 Calcipressin DUF4523 PF15023.1 CBZ49912.1 - 0.075 12.5 0.0 0.36 10.3 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4523) Ribosomal_L28 PF00830.14 CBZ49914.1 - 7.7e-21 73.6 1.9 4.8e-20 71.1 1.0 2.2 2 0 0 2 2 2 1 Ribosomal L28 family DUF4149 PF13664.1 CBZ49915.1 - 2.5e-14 53.1 2.3 2.5e-14 53.1 1.6 2.2 1 1 1 2 2 2 1 Domain of unknown function (DUF4149) SNF2_N PF00176.18 CBZ49916.1 - 2.8e-06 26.3 0.0 2.5e-05 23.2 0.0 2.2 2 1 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C_2 PF13307.1 CBZ49919.1 - 9.2e-48 162.3 0.0 6.5e-47 159.5 0.0 2.2 1 1 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.10 CBZ49919.1 - 2.5e-34 118.1 0.0 7.6e-29 100.3 0.0 2.3 2 0 0 2 2 2 2 DEAD_2 zf-C3HC4_3 PF13920.1 CBZ49919.1 - 1.9e-06 27.4 7.7 5e-06 26.0 5.3 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) ResIII PF04851.10 CBZ49919.1 - 8.9e-06 25.6 0.1 0.0015 18.3 0.0 3.2 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit zf-C3HC4_2 PF13923.1 CBZ49919.1 - 4.2e-05 23.4 9.9 0.00015 21.7 6.9 2.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CBZ49919.1 - 5.1e-05 23.0 10.1 0.00018 21.2 7.0 2.1 1 0 0 1 1 1 1 Ring finger domain DEAD PF00270.24 CBZ49919.1 - 0.00018 21.0 0.0 0.03 13.8 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase zf-C3HC4 PF00097.20 CBZ49919.1 - 0.00043 19.8 9.2 0.0012 18.5 6.4 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBZ49919.1 - 0.0013 18.4 7.5 0.0037 16.9 5.2 1.9 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_4 PF14570.1 CBZ49919.1 - 0.012 15.2 6.7 0.032 13.7 4.7 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.1 CBZ49919.1 - 0.031 14.1 11.5 0.034 14.0 6.5 2.3 2 0 0 2 2 1 0 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.1 CBZ49919.1 - 0.16 11.5 4.0 0.37 10.3 2.8 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 PhoH PF02562.11 CBZ49919.1 - 0.36 10.0 0.0 3.9 6.6 0.0 2.1 2 0 0 2 2 2 0 PhoH-like protein zf-rbx1 PF12678.2 CBZ49919.1 - 4.7 7.3 10.6 0.25 11.4 3.1 2.1 2 0 0 2 2 2 0 RING-H2 zinc finger Radical_SAM PF04055.16 CBZ49920.1 - 4.4e-10 39.9 0.0 9.5e-10 38.8 0.0 1.6 2 0 0 2 2 2 1 Radical SAM superfamily Fer4_14 PF13394.1 CBZ49920.1 - 0.00034 20.6 0.0 0.00099 19.1 0.0 1.8 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_12 PF13353.1 CBZ49920.1 - 0.0017 18.4 0.4 0.0035 17.4 0.1 1.7 2 0 0 2 2 1 1 4Fe-4S single cluster domain RNase_H2_suC PF08615.6 CBZ49920.1 - 0.024 14.4 0.6 0.061 13.1 0.1 1.8 2 0 0 2 2 2 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) VID27 PF08553.5 CBZ49920.1 - 0.39 8.8 10.9 0.69 8.0 7.6 1.3 1 0 0 1 1 1 0 VID27 cytoplasmic protein Ycf1 PF05758.7 CBZ49920.1 - 0.65 7.6 3.2 0.82 7.3 2.2 1.1 1 0 0 1 1 1 0 Ycf1 Spore_coat_CotO PF14153.1 CBZ49920.1 - 1.4 8.3 12.3 0.21 11.0 5.8 1.6 2 0 0 2 2 2 0 Spore coat protein CotO Cytomega_UL84 PF06284.6 CBZ49920.1 - 2.5 6.4 8.7 4.6 5.5 6.1 1.3 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein DUF1510 PF07423.6 CBZ49920.1 - 4.2 6.6 22.0 0.24 10.7 10.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) Myc_N PF01056.13 CBZ49920.1 - 4.8 6.2 18.6 5.8 5.9 7.0 2.5 2 0 0 2 2 2 0 Myc amino-terminal region PBP1_TM PF14812.1 CBZ49920.1 - 7.6 6.9 20.8 11 6.4 7.6 3.3 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal FAM176 PF14851.1 CBZ49920.1 - 7.6 6.1 17.1 5.3 6.7 6.1 2.6 2 0 0 2 2 2 0 FAM176 family Form_Nir_trans PF01226.12 CBZ49921.1 - 3e-75 252.3 13.8 3.7e-75 252.0 9.6 1.1 1 0 0 1 1 1 1 Formate/nitrite transporter TrbC PF04956.8 CBZ49921.1 - 0.027 14.4 1.4 0.081 12.9 0.5 2.1 2 0 0 2 2 2 0 TrbC/VIRB2 family SNARE PF05739.14 CBZ49923.1 - 1.1e-16 60.2 2.3 1.1e-16 60.2 1.6 2.2 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.20 CBZ49923.1 - 5.1e-05 23.3 0.9 5.1e-05 23.3 0.6 2.3 2 0 0 2 2 2 1 Syntaxin MCPsignal PF00015.16 CBZ49923.1 - 0.00013 21.6 4.3 0.00018 21.1 0.4 2.2 2 1 0 2 2 2 1 Methyl-accepting chemotaxis protein (MCP) signalling domain Sirohm_synth_C PF14823.1 CBZ49923.1 - 0.0053 16.0 0.3 2.6 7.4 0.1 2.7 2 0 0 2 2 2 1 Sirohaem biosynthesis protein C-terminal NHR2 PF08788.6 CBZ49923.1 - 0.02 14.3 0.0 0.05 13.0 0.0 1.7 1 0 0 1 1 1 0 NHR2 domain like Reo_sigmaC PF04582.7 CBZ49923.1 - 0.02 14.0 0.6 0.028 13.6 0.1 1.4 2 0 0 2 2 2 0 Reovirus sigma C capsid protein PBP1_TM PF14812.1 CBZ49923.1 - 0.025 14.9 0.8 0.24 11.7 0.1 2.4 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal WXG100 PF06013.7 CBZ49923.1 - 0.031 14.2 2.4 3.6 7.6 0.7 3.0 2 1 0 2 2 2 0 Proteins of 100 residues with WXG NPV_P10 PF05531.7 CBZ49923.1 - 0.089 13.0 0.9 14 6.0 0.3 2.7 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Mit_KHE1 PF10173.4 CBZ49923.1 - 0.093 12.5 4.1 0.2 11.4 2.8 1.6 1 1 0 1 1 1 0 Mitochondrial K+-H+ exchange-related DUF1664 PF07889.7 CBZ49923.1 - 0.32 10.8 7.4 0.21 11.3 1.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) DUF1178 PF06676.6 CBZ49923.1 - 1.3 9.2 4.5 0.26 11.4 0.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1178) Synaptobrevin PF00957.16 CBZ49923.1 - 1.8 8.2 5.8 0.3 10.6 0.8 2.1 3 0 0 3 3 3 0 Synaptobrevin Syntaxin_2 PF14523.1 CBZ49923.1 - 2.3 8.2 8.3 0.73 9.9 0.3 2.4 2 0 0 2 2 2 0 Syntaxin-like protein MCM_N PF14551.1 CBZ49923.1 - 5 7.6 5.9 43 4.6 4.1 2.2 1 1 0 1 1 1 0 MCM N-terminal domain EMP24_GP25L PF01105.19 CBZ49923.1 - 5.5 6.6 7.0 0.53 9.9 0.8 2.3 2 2 1 3 3 3 0 emp24/gp25L/p24 family/GOLD FliJ PF02050.11 CBZ49923.1 - 6.6 6.8 14.6 3.5 7.6 6.2 2.2 2 0 0 2 2 2 0 Flagellar FliJ protein DUF2951 PF11166.3 CBZ49923.1 - 6.6 6.6 7.1 2.8 7.8 0.4 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2951) LRR_6 PF13516.1 CBZ49924.1 - 3e-07 29.8 4.1 0.81 9.9 0.1 5.8 5 0 0 5 5 5 2 Leucine Rich repeat LRR_7 PF13504.1 CBZ49924.1 - 3.3 8.3 5.2 67 4.3 0.0 3.8 4 0 0 4 4 4 0 Leucine rich repeat RRM_1 PF00076.17 CBZ49925.1 - 2e-15 56.1 0.0 2.1e-08 33.6 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBZ49925.1 - 7.2e-09 35.3 0.0 7.1e-06 25.7 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBZ49925.1 - 5.7e-07 29.4 0.0 0.028 14.3 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) SRP40_C PF05022.7 CBZ49926.1 - 1e-25 90.0 2.6 1e-25 90.0 1.8 2.3 3 0 0 3 3 3 1 SRP40, C-terminal domain Hid1 PF12722.2 CBZ49926.1 - 2.6 5.6 10.5 3.3 5.2 7.3 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Hydrolase_6 PF13344.1 CBZ49927.1 - 5.8e-35 119.2 0.0 1.3e-34 118.1 0.0 1.6 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 CBZ49927.1 - 1e-11 44.3 0.0 2.7e-11 43.0 0.0 1.7 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 CBZ49927.1 - 6.7e-07 29.9 0.0 5.7e-05 23.6 0.0 2.7 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase PGP_phosphatase PF09419.5 CBZ49927.1 - 0.0091 15.3 0.0 0.021 14.1 0.0 1.6 1 0 0 1 1 1 1 Mitochondrial PGP phosphatase HAD_2 PF13419.1 CBZ49927.1 - 0.011 16.0 0.0 24 5.0 0.0 3.1 2 1 1 3 3 3 0 Haloacid dehalogenase-like hydrolase RCC1 PF00415.13 CBZ49928.1 - 3.2e-23 81.6 14.8 9.4e-07 28.9 0.2 8.0 8 0 0 8 8 8 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 CBZ49928.1 - 1.4e-13 50.0 48.7 1.7e-07 30.6 2.9 6.6 7 0 0 7 7 7 4 Regulator of chromosome condensation (RCC1) repeat zf-His_Me_endon PF05551.6 CBZ49930.1 - 0.028 14.3 0.0 0.043 13.7 0.0 1.3 1 0 0 1 1 1 0 Zinc-binding loop region of homing endonuclease PNPOx_C PF10590.4 CBZ49930.1 - 0.14 11.7 0.1 0.26 10.8 0.1 1.4 1 0 0 1 1 1 0 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Histone PF00125.19 CBZ49932.1 - 1.5e-20 73.0 0.4 2.2e-20 72.5 0.3 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 CBZ49932.1 - 0.00013 22.0 0.6 0.00018 21.4 0.0 1.5 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.8 CBZ49932.1 - 0.00068 19.8 0.0 0.001 19.3 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A Asr PF06392.6 CBZ49932.1 - 0.27 11.6 5.8 0.54 10.6 4.0 1.5 1 0 0 1 1 1 0 Acid shock protein repeat PAN_1 PF00024.21 CBZ49933.1 - 2e-55 184.4 69.2 2.8e-08 33.3 2.2 8.3 7 1 1 8 8 8 8 PAN domain PAN_4 PF14295.1 CBZ49933.1 - 6.7e-44 147.3 67.1 4.3e-06 26.3 1.8 8.8 8 0 0 8 8 8 8 PAN domain DUF1923 PF09083.5 CBZ49933.1 - 0.003 16.9 0.0 31 4.1 0.0 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF1923) HOK_GEF PF01848.11 CBZ49933.1 - 0.012 14.8 0.2 44 3.5 0.0 3.3 3 0 0 3 3 3 0 Hok/gef family Mastoparan PF08249.6 CBZ49933.1 - 0.1 13.1 0.7 49 4.8 0.0 3.3 3 0 0 3 3 3 0 Mastoparan protein Phage_GPD PF05954.6 CBZ49933.1 - 0.13 11.4 0.0 72 2.4 0.0 3.0 3 0 0 3 3 3 0 Phage late control gene D protein (GPD) Polyoma_lg_T_C PF06431.6 CBZ49933.1 - 0.16 10.6 8.7 8.8 4.8 0.2 3.1 3 0 0 3 3 3 0 Polyomavirus large T antigen C-terminus Anp1 PF03452.9 CBZ49933.1 - 0.19 10.8 0.0 85 2.1 0.0 3.1 3 0 0 3 3 3 0 Anp1 EamA PF00892.15 CBZ49934.1 - 1.7e-07 31.2 11.7 0.00022 21.2 0.3 3.5 3 1 0 3 3 3 2 EamA-like transporter family UAA PF08449.6 CBZ49934.1 - 2.8e-06 26.4 1.7 3.6e-06 26.1 1.2 1.3 1 0 0 1 1 1 1 UAA transporter family Nuc_sug_transp PF04142.10 CBZ49934.1 - 8.8e-06 24.9 3.2 1.6e-05 24.1 2.2 1.4 1 1 0 1 1 1 1 Nucleotide-sugar transporter DUF420 PF04238.7 CBZ49934.1 - 0.0065 16.4 0.1 0.029 14.3 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF420) DUF1129 PF06570.6 CBZ49934.1 - 0.012 14.9 1.1 0.021 14.1 0.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) DUF4118 PF13493.1 CBZ49934.1 - 0.041 14.0 2.1 0.041 14.0 1.5 2.4 4 0 0 4 4 4 0 Domain of unknown function (DUF4118) Thioredoxin PF00085.15 CBZ49935.1 - 5.1e-24 83.9 0.3 3.7e-13 49.0 0.0 3.3 3 0 0 3 3 3 3 Thioredoxin Thioredoxin_6 PF13848.1 CBZ49935.1 - 8.4e-09 35.4 4.6 0.0004 20.2 0.4 3.4 3 1 0 3 3 3 3 Thioredoxin-like domain HyaE PF07449.6 CBZ49935.1 - 1.6e-05 24.7 0.1 0.052 13.4 0.0 3.6 3 2 0 3 3 3 2 Hydrogenase-1 expression protein HyaE Thioredoxin_8 PF13905.1 CBZ49935.1 - 0.00013 21.9 1.9 1.2 9.2 0.1 3.7 3 1 1 4 4 4 1 Thioredoxin-like Thioredoxin_2 PF13098.1 CBZ49935.1 - 0.00044 20.4 1.5 1 9.5 0.0 3.0 3 1 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_7 PF13899.1 CBZ49935.1 - 0.022 14.7 1.3 0.26 11.3 0.0 2.8 3 0 0 3 3 3 0 Thioredoxin-like TrbC_Ftype PF09673.5 CBZ49935.1 - 0.084 12.4 0.0 0.96 9.0 0.0 2.7 2 0 0 2 2 2 0 Type-F conjugative transfer system pilin assembly protein Glycos_transf_1 PF00534.15 CBZ49936.1 - 5.1e-39 133.4 0.0 7.8e-39 132.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 CBZ49936.1 - 2.5e-22 79.7 3.2 1.8e-20 73.6 0.0 4.2 4 0 0 4 4 4 1 Glycosyl transferase 4-like domain Glyco_transf_4 PF13439.1 CBZ49936.1 - 3.3e-19 69.2 0.8 1e-18 67.7 0.5 1.9 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.1 CBZ49936.1 - 9.3e-14 51.7 0.0 2.6e-13 50.2 0.0 1.8 1 0 0 1 1 1 1 Glycosyl transferases group 1 CBM_48 PF02922.13 CBZ49936.1 - 6.9e-13 48.4 0.2 7.4e-07 29.1 0.0 2.5 1 1 0 2 2 2 2 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Glyco_transf_5 PF08323.6 CBZ49936.1 - 1.2e-12 47.8 2.0 7.7e-05 22.3 0.0 3.4 2 1 1 3 3 3 2 Starch synthase catalytic domain Alpha-amylase_C PF02806.13 CBZ49936.1 - 1.2e-10 41.4 0.0 3.7e-10 39.8 0.0 1.9 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain Alpha-amylase PF00128.19 CBZ49936.1 - 7e-07 28.9 0.0 1.9e-05 24.2 0.0 2.2 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Glyco_trans_1_2 PF13524.1 CBZ49936.1 - 0.00074 19.7 0.0 0.0021 18.2 0.0 1.8 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycogen_syn PF05693.8 CBZ49936.1 - 0.017 13.4 0.3 0.089 11.0 0.1 2.0 2 0 0 2 2 2 0 Glycogen synthase ubiquitin PF00240.18 CBZ49936.1 - 0.028 13.8 0.2 0.052 12.9 0.1 1.4 1 0 0 1 1 1 0 Ubiquitin family Spc97_Spc98 PF04130.8 CBZ49937.1 - 6e-46 156.8 0.0 7.7e-19 67.4 0.0 4.4 3 1 1 4 4 4 3 Spc97 / Spc98 family Spore_coat_CotO PF14153.1 CBZ49937.1 - 2.2 7.7 15.0 0.24 10.7 5.8 2.3 2 0 0 2 2 2 0 Spore coat protein CotO Nop14 PF04147.7 CBZ49937.1 - 5.1 4.8 16.5 11 3.7 11.5 1.5 1 0 0 1 1 1 0 Nop14-like family Kinase-like PF14531.1 CBZ49938.1 - 1.9e-30 105.8 0.0 3.1e-30 105.1 0.0 1.3 1 1 0 1 1 1 1 Kinase-like Pkinase PF00069.20 CBZ49938.1 - 1.2e-16 60.6 0.0 2.1e-16 59.8 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ49938.1 - 3.1e-09 36.3 0.0 4.1e-05 22.7 0.0 2.0 2 0 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.9 CBZ49938.1 - 0.11 11.5 0.0 0.21 10.6 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family HABP4_PAI-RBP1 PF04774.10 CBZ49941.1 - 5.5e-11 42.9 16.8 5.5e-11 42.9 11.7 3.4 3 1 1 4 4 4 1 Hyaluronan / mRNA binding family Tankyrase_bdg_C PF15327.1 CBZ49941.1 - 0.02 15.1 0.6 0.02 15.1 0.4 2.4 1 1 1 2 2 2 0 Tankyrase binding protein C terminal domain Glyco_transf_22 PF03901.12 CBZ49942.1 - 2.1e-80 270.7 0.0 2.7e-80 270.4 0.0 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Pkinase PF00069.20 CBZ49943.1 - 2.6e-07 30.0 0.0 2.7e-06 26.7 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain AAA PF00004.24 CBZ49944.1 - 3.2e-93 308.8 0.0 1.7e-45 154.4 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 CBZ49944.1 - 1.7e-13 50.1 0.0 3.6e-05 22.9 0.0 3.3 3 1 0 3 3 3 2 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 CBZ49944.1 - 2.9e-13 50.2 0.1 4.6e-06 26.7 0.0 3.2 2 1 1 3 3 3 2 AAA ATPase domain AAA_33 PF13671.1 CBZ49944.1 - 9.5e-13 48.2 0.0 3.2e-06 27.0 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 CBZ49944.1 - 7.1e-12 45.6 0.8 0.00082 19.5 0.3 4.2 2 2 0 2 2 2 2 AAA domain AAA_2 PF07724.9 CBZ49944.1 - 6.5e-11 42.4 0.0 0.00029 20.7 0.0 3.3 3 0 0 3 3 3 2 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 CBZ49944.1 - 7e-11 42.0 0.0 7.9e-06 25.6 0.0 2.9 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 CBZ49944.1 - 1.3e-10 42.1 0.3 0.0019 18.9 0.0 3.7 3 2 0 3 3 3 2 AAA domain AAA_14 PF13173.1 CBZ49944.1 - 8.1e-10 38.6 0.0 0.00051 19.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.7 CBZ49944.1 - 9.9e-10 37.8 0.1 0.00018 20.6 0.0 3.0 3 0 0 3 3 3 2 Zeta toxin Bac_DnaA PF00308.13 CBZ49944.1 - 6.4e-09 35.7 0.0 2.7e-05 23.9 0.0 2.8 2 1 0 2 2 2 2 Bacterial dnaA protein NACHT PF05729.7 CBZ49944.1 - 7.6e-08 32.1 0.7 0.042 13.5 0.0 3.5 3 0 0 3 3 3 2 NACHT domain TIP49 PF06068.8 CBZ49944.1 - 8.2e-08 31.3 0.0 0.0017 17.1 0.0 2.7 2 0 0 2 2 2 2 TIP49 C-terminus RNA_helicase PF00910.17 CBZ49944.1 - 1.1e-07 31.9 0.0 0.014 15.5 0.0 2.7 2 0 0 2 2 2 2 RNA helicase IstB_IS21 PF01695.12 CBZ49944.1 - 2e-07 30.6 0.2 0.019 14.3 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_28 PF13521.1 CBZ49944.1 - 5.1e-07 29.7 0.0 0.048 13.6 0.0 3.0 2 0 0 2 2 2 2 AAA domain ABC_tran PF00005.22 CBZ49944.1 - 5.7e-07 29.9 0.2 0.054 13.7 0.1 2.9 2 1 0 2 2 2 2 ABC transporter Viral_helicase1 PF01443.13 CBZ49944.1 - 7.5e-07 28.9 0.0 0.01 15.3 0.0 2.5 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase CDC48_N PF02359.13 CBZ49944.1 - 7.6e-07 28.9 0.0 2.1e-06 27.6 0.0 1.8 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain AAA_18 PF13238.1 CBZ49944.1 - 3.2e-06 27.4 0.1 0.11 12.8 0.0 3.2 3 0 0 3 3 2 2 AAA domain DUF815 PF05673.8 CBZ49944.1 - 4.3e-06 25.8 0.0 0.063 12.2 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF815) Sigma54_activ_2 PF14532.1 CBZ49944.1 - 5.2e-06 26.5 0.0 0.026 14.5 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain Arch_ATPase PF01637.13 CBZ49944.1 - 5.5e-06 26.2 0.0 0.12 12.0 0.0 3.5 2 1 1 3 3 3 1 Archaeal ATPase Mg_chelatase PF01078.16 CBZ49944.1 - 6.8e-06 25.3 0.3 0.02 14.0 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_19 PF13245.1 CBZ49944.1 - 7.2e-06 25.6 1.0 0.12 12.1 0.0 3.1 3 0 0 3 3 2 2 Part of AAA domain Sigma54_activat PF00158.21 CBZ49944.1 - 8.6e-06 25.3 0.3 0.017 14.5 0.1 2.9 2 1 0 2 2 2 2 Sigma-54 interaction domain NB-ARC PF00931.17 CBZ49944.1 - 1e-05 24.5 0.1 0.12 11.1 0.0 2.3 2 0 0 2 2 2 2 NB-ARC domain KaiC PF06745.8 CBZ49944.1 - 0.00011 21.4 0.6 0.39 9.8 0.0 3.1 2 1 1 3 3 3 2 KaiC UPF0079 PF02367.12 CBZ49944.1 - 0.00026 20.5 0.6 0.28 10.8 0.0 2.9 3 0 0 3 3 3 1 Uncharacterised P-loop hydrolase UPF0079 DUF2075 PF09848.4 CBZ49944.1 - 0.0003 19.8 0.0 0.13 11.1 0.0 2.5 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) PhoH PF02562.11 CBZ49944.1 - 0.00031 20.0 0.8 0.89 8.7 0.1 2.9 2 1 0 2 2 2 2 PhoH-like protein Cytidylate_kin2 PF13189.1 CBZ49944.1 - 0.00031 20.6 0.0 0.15 11.9 0.0 2.5 2 0 0 2 2 2 1 Cytidylate kinase-like family SKI PF01202.17 CBZ49944.1 - 0.00037 20.3 0.0 1.4 8.7 0.0 2.8 2 0 0 2 2 2 2 Shikimate kinase AAA_3 PF07726.6 CBZ49944.1 - 0.00072 19.1 0.0 1.4 8.5 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.10 CBZ49944.1 - 0.00075 19.2 0.2 0.39 10.3 0.0 2.9 2 1 0 2 2 2 1 NTPase AAA_25 PF13481.1 CBZ49944.1 - 0.00077 18.9 5.5 0.39 10.0 0.1 4.0 2 2 1 3 3 3 1 AAA domain Parvo_NS1 PF01057.12 CBZ49944.1 - 0.00083 18.3 0.0 0.25 10.1 0.0 2.2 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 AAA_24 PF13479.1 CBZ49944.1 - 0.0032 17.0 0.0 0.23 10.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain PduV-EutP PF10662.4 CBZ49944.1 - 0.0034 16.8 0.0 1.8 8.0 0.0 2.4 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation ResIII PF04851.10 CBZ49944.1 - 0.012 15.4 0.0 5.9 6.6 0.0 2.6 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit ATP-synt_ab PF00006.20 CBZ49944.1 - 0.015 14.7 0.0 3.7 6.9 0.0 2.4 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain T2SE PF00437.15 CBZ49944.1 - 0.022 13.6 0.0 7.6 5.3 0.0 2.7 3 0 0 3 3 3 0 Type II/IV secretion system protein Rad17 PF03215.10 CBZ49944.1 - 0.028 13.0 0.0 5.1 5.6 0.0 2.1 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein CPT PF07931.7 CBZ49944.1 - 0.036 13.6 0.3 0.95 9.0 0.0 3.0 3 1 0 3 3 2 0 Chloramphenicol phosphotransferase-like protein AAA_29 PF13555.1 CBZ49944.1 - 0.061 12.8 0.1 9.2 5.8 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_10 PF12846.2 CBZ49944.1 - 0.065 12.6 0.8 8.2 5.7 0.0 3.3 4 0 0 4 4 4 0 AAA-like domain AAA_30 PF13604.1 CBZ49944.1 - 0.071 12.6 0.1 14 5.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain Vps4_C PF09336.5 CBZ49944.1 - 0.12 12.2 0.3 5.2 7.0 0.0 3.1 3 0 0 3 3 2 0 Vps4 C terminal oligomerisation domain AAA_23 PF13476.1 CBZ49944.1 - 0.17 12.1 0.0 28 4.9 0.0 2.6 2 0 0 2 2 2 0 AAA domain Torsin PF06309.6 CBZ49944.1 - 0.2 11.5 0.1 4.9 7.0 0.0 2.4 2 0 0 2 2 2 0 Torsin PIF1 PF05970.9 CBZ49944.1 - 0.2 10.5 0.0 5.6 5.8 0.0 2.4 2 0 0 2 2 2 0 PIF1-like helicase RRM_1 PF00076.17 CBZ49945.1 - 8e-08 31.8 0.0 1.4e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBZ49945.1 - 3.3e-06 26.9 0.0 5.5e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBZ49945.1 - 0.0011 18.7 0.0 0.002 17.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4651 PF15513.1 CBZ49945.1 - 0.0076 15.6 0.1 0.022 14.1 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4651) Nup35_RRM_2 PF14605.1 CBZ49945.1 - 0.05 13.3 0.0 0.088 12.5 0.0 1.3 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif DUF2201_N PF13203.1 CBZ49945.1 - 0.092 11.8 1.5 0.11 11.6 1.0 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain Dynamin_M PF01031.15 CBZ49946.1 - 2.9e-86 288.9 0.0 5.1e-86 288.1 0.0 1.4 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.18 CBZ49946.1 - 6.2e-48 162.7 0.0 1.2e-47 161.8 0.0 1.5 1 0 0 1 1 1 1 Dynamin family GED PF02212.13 CBZ49946.1 - 1.1e-22 79.6 0.6 4.7e-22 77.6 0.2 2.4 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 CBZ49946.1 - 0.0018 18.2 0.0 0.0075 16.2 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 CBZ49946.1 - 0.022 15.2 0.0 0.068 13.6 0.0 1.9 1 0 0 1 1 1 0 Miro-like protein FtsK_SpoIIIE PF01580.13 CBZ49946.1 - 0.023 14.1 0.1 15 4.9 0.2 4.1 4 1 1 5 5 5 0 FtsK/SpoIIIE family AAA_17 PF13207.1 CBZ49946.1 - 0.068 13.9 0.0 0.25 12.1 0.0 2.0 1 0 0 1 1 1 0 AAA domain DUF4539 PF15072.1 CBZ49947.1 - 4.3e-29 100.0 0.0 7e-29 99.3 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4539) V_ATPase_I PF01496.14 CBZ49948.1 - 7.1 4.3 4.1 9.9 3.8 2.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF2611 PF11022.3 CBZ49949.1 - 0.092 12.8 0.1 0.22 11.6 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2611) EmrE PF13536.1 CBZ49949.1 - 0.2 11.8 11.9 0.034 14.3 5.3 1.8 2 0 0 2 2 2 0 Multidrug resistance efflux transporter FabA PF07977.8 CBZ49950.1 - 2.9e-34 117.4 0.1 3.7e-34 117.1 0.0 1.1 1 0 0 1 1 1 1 FabA-like domain MaoC_dehydratas PF01575.14 CBZ49950.1 - 0.0089 15.4 0.0 0.015 14.6 0.0 1.3 1 0 0 1 1 1 1 MaoC like domain CTD_bind PF04818.8 CBZ49951.1 - 3.9e-14 52.6 0.0 9e-14 51.4 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase II-binding domain. zf-CCHC PF00098.18 CBZ49951.1 - 8.5e-08 31.7 2.0 1.5e-07 31.0 1.4 1.4 1 0 0 1 1 1 1 Zinc knuckle Surp PF01805.15 CBZ49951.1 - 7.9e-06 25.4 0.0 3.7e-05 23.2 0.0 2.2 2 0 0 2 2 2 1 Surp module zf-CCHC_2 PF13696.1 CBZ49951.1 - 0.028 13.8 0.4 0.096 12.1 0.3 1.9 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_4 PF14392.1 CBZ49951.1 - 0.061 12.9 0.6 0.11 12.2 0.4 1.3 1 0 0 1 1 1 0 Zinc knuckle Peptidase_C1 PF00112.18 CBZ49954.1 - 1.7e-73 247.1 1.5 3.2e-73 246.2 1.0 1.4 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.7 CBZ49954.1 - 3.6e-17 62.3 2.6 7.3e-17 61.3 1.8 1.5 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.10 CBZ49954.1 - 6.6e-05 21.6 4.1 0.0043 15.6 0.9 2.2 2 0 0 2 2 2 2 Peptidase C1-like family CS PF04969.11 CBZ49955.1 - 1.8e-10 41.1 0.3 2.7e-10 40.6 0.2 1.3 1 0 0 1 1 1 1 CS domain Fork_head_N PF08430.7 CBZ49955.1 - 1 9.7 8.3 1.6 9.1 5.7 1.2 1 0 0 1 1 1 0 Forkhead N-terminal region RRM_1 PF00076.17 CBZ49956.1 - 3.8e-54 180.2 1.3 4.1e-17 61.5 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBZ49956.1 - 1.1e-37 127.8 1.2 2.2e-11 43.5 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBZ49956.1 - 1.5e-30 104.8 2.0 6.2e-10 38.7 0.1 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WW PF00397.21 CBZ49956.1 - 1.2e-09 37.8 5.7 2.6e-09 36.7 3.9 1.6 1 0 0 1 1 1 1 WW domain RNA_bind PF08675.6 CBZ49956.1 - 0.00017 21.5 0.0 0.015 15.2 0.0 3.0 3 0 0 3 3 3 1 RNA binding domain DUF4651 PF15513.1 CBZ49956.1 - 0.081 12.3 0.1 0.39 10.1 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4651) SAG PF04092.8 CBZ49957.1 - 4.2e-56 188.6 22.0 3e-33 114.8 6.2 2.1 2 0 0 2 2 2 2 SRS domain SAG PF04092.8 CBZ49958.1 - 2.1e-52 176.7 19.0 5.1e-30 104.4 3.3 2.1 2 0 0 2 2 2 2 SRS domain SAG PF04092.8 CBZ49959.1 - 3.5e-53 179.2 18.0 5.2e-30 104.3 3.3 2.1 2 0 0 2 2 2 2 SRS domain NKAIN PF05640.9 CBZ49959.1 - 0.063 12.2 0.0 1.2 8.0 0.0 2.2 2 0 0 2 2 2 0 Na,K-Atpase Interacting protein SAG PF04092.8 CBZ49960.1 - 3.3e-49 166.3 14.9 1.5e-29 102.9 1.6 2.1 2 0 0 2 2 2 2 SRS domain SAG PF04092.8 CBZ49961.1 - 2e-52 176.7 18.0 5.4e-30 104.3 3.4 2.2 2 0 0 2 2 2 2 SRS domain NKAIN PF05640.9 CBZ49961.1 - 0.078 11.9 0.0 1.1 8.1 0.0 2.1 2 0 0 2 2 2 0 Na,K-Atpase Interacting protein Laminin_G_2 PF02210.19 CBZ49961.1 - 0.079 13.0 0.0 5.2 7.1 0.0 2.4 2 0 0 2 2 2 0 Laminin G domain SAG PF04092.8 CBZ49962.1 - 5.8e-53 178.5 19.7 3.4e-33 114.6 5.1 2.1 2 0 0 2 2 2 2 SRS domain DUF3277 PF11681.3 CBZ49962.1 - 0.024 14.1 3.3 0.045 13.2 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3277) SAG PF04092.8 CBZ49963.1 - 8.9e-58 194.0 13.7 5e-35 120.6 0.7 2.1 2 0 0 2 2 2 2 SRS domain DUF3277 PF11681.3 CBZ49963.1 - 0.051 13.0 0.0 0.12 11.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3277) SAG PF04092.8 CBZ49964.1 - 1.3e-57 193.5 21.5 3.5e-34 117.8 2.3 2.1 2 0 0 2 2 2 2 SRS domain YfhO PF09586.5 CBZ49964.1 - 0.029 12.3 0.0 0.04 11.9 0.0 1.1 1 0 0 1 1 1 0 Bacterial membrane protein YfhO SAG PF04092.8 CBZ49965.1 - 3e-58 195.6 16.6 2.4e-34 118.4 1.2 2.1 2 0 0 2 2 2 2 SRS domain SAG PF04092.8 CBZ49966.1 - 1.7e-54 183.4 17.5 1.1e-32 113.0 4.7 2.1 2 0 0 2 2 2 2 SRS domain DUF3277 PF11681.3 CBZ49966.1 - 0.015 14.8 0.1 0.04 13.4 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3277) SAG PF04092.8 CBZ49967.1 - 2.9e-56 189.1 20.4 4.3e-32 111.1 3.5 2.1 2 0 0 2 2 2 2 SRS domain DUF3277 PF11681.3 CBZ49967.1 - 0.033 13.6 0.1 0.07 12.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3277) SAG PF04092.8 CBZ49968.1 - 7.2e-56 187.9 17.7 1.8e-33 115.5 1.7 2.1 2 0 0 2 2 2 2 SRS domain DUF3277 PF11681.3 CBZ49968.1 - 0.034 13.6 0.1 0.079 12.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3277) SAG PF04092.8 CBZ49969.1 - 4.1e-56 188.7 19.9 1.7e-33 115.6 2.6 2.1 2 0 0 2 2 2 2 SRS domain DUF3277 PF11681.3 CBZ49969.1 - 0.036 13.5 0.1 0.08 12.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3277) SAG PF04092.8 CBZ49970.1 - 1.1e-54 184.1 18.2 1.2e-32 112.9 4.5 2.1 2 0 0 2 2 2 2 SRS domain DUF3277 PF11681.3 CBZ49970.1 - 0.016 14.7 0.1 0.039 13.4 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3277) DUF4547 PF15080.1 CBZ49971.1 - 4.8 6.5 0.1 8.3 5.7 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4547) SNF2_N PF00176.18 CBZ49972.1 - 2e-67 227.1 0.0 1.9e-66 223.8 0.0 2.2 1 1 0 1 1 1 1 SNF2 family N-terminal domain SLIDE PF09111.5 CBZ49972.1 - 5.4e-36 122.8 0.2 1.8e-35 121.2 0.1 2.0 1 0 0 1 1 1 1 SLIDE Helicase_C PF00271.26 CBZ49972.1 - 6.4e-16 57.9 0.0 1.5e-15 56.7 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 CBZ49972.1 - 3.4e-10 40.0 0.1 6.7e-09 35.8 0.0 2.8 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.3 CBZ49972.1 - 9.7e-06 24.6 0.1 5.5e-05 22.1 0.1 2.1 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 DEAD PF00270.24 CBZ49972.1 - 0.0006 19.3 2.0 0.012 15.1 0.0 3.4 4 0 0 4 4 4 1 DEAD/DEAH box helicase Myb_DNA-binding PF00249.26 CBZ49972.1 - 0.023 14.7 0.4 7.6 6.6 0.0 3.5 3 0 0 3 3 3 0 Myb-like DNA-binding domain HAND PF09110.6 CBZ49972.1 - 0.07 13.5 2.9 0.9 9.9 2.0 2.8 1 1 0 1 1 1 0 HAND Rad51 PF08423.6 CBZ49973.1 - 1.2e-08 34.1 0.5 0.0017 17.2 0.0 4.1 4 0 0 4 4 4 2 Rad51 KaiC PF06745.8 CBZ49973.1 - 1.2e-07 31.0 0.0 4.2e-06 26.0 0.0 2.2 2 0 0 2 2 2 1 KaiC AAA_25 PF13481.1 CBZ49973.1 - 2.5e-07 30.3 0.1 1.8e-05 24.2 0.0 3.0 2 1 0 2 2 2 1 AAA domain RecA PF00154.16 CBZ49973.1 - 3.3e-05 23.0 0.0 0.00048 19.2 0.0 2.0 2 0 0 2 2 2 1 recA bacterial DNA recombination protein NACHT PF05729.7 CBZ49973.1 - 0.014 15.1 0.0 0.11 12.1 0.0 2.1 2 0 0 2 2 2 0 NACHT domain AAA_19 PF13245.1 CBZ49973.1 - 0.019 14.6 0.0 0.074 12.8 0.0 2.0 1 1 0 1 1 1 0 Part of AAA domain DUF2285 PF10074.4 CBZ49973.1 - 0.041 14.2 0.0 0.12 12.7 0.0 1.7 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2285) NB-ARC PF00931.17 CBZ49973.1 - 0.056 12.3 0.0 0.087 11.6 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain Kelch_3 PF13415.1 CBZ49974.1 - 3.1e-26 90.8 7.0 4.8e-09 36.1 0.0 4.6 4 0 0 4 4 4 3 Galactose oxidase, central domain Kelch_4 PF13418.1 CBZ49974.1 - 1.1e-19 69.9 9.8 0.0005 19.7 0.0 4.6 4 0 0 4 4 4 4 Galactose oxidase, central domain Kelch_5 PF13854.1 CBZ49974.1 - 1.3e-13 50.5 0.1 0.00074 19.4 0.0 5.0 5 0 0 5 5 5 2 Kelch motif Kelch_6 PF13964.1 CBZ49974.1 - 2.2e-13 49.7 4.1 0.00044 20.3 0.0 4.8 4 1 1 5 5 4 3 Kelch motif Kelch_1 PF01344.20 CBZ49974.1 - 1.4e-10 40.4 8.6 0.2 11.2 0.0 5.8 5 1 0 5 5 5 3 Kelch motif PspA_IM30 PF04012.7 CBZ49974.1 - 1.4e-05 24.5 13.0 4.5e-05 22.9 9.0 1.7 1 1 0 1 1 1 1 PspA/IM30 family Kelch_2 PF07646.10 CBZ49974.1 - 6.9e-05 22.4 4.9 1.1 9.1 0.0 4.5 4 1 0 4 4 4 1 Kelch motif FlaC_arch PF05377.6 CBZ49974.1 - 0.0026 17.5 3.1 0.14 12.0 0.1 3.3 3 0 0 3 3 3 1 Flagella accessory protein C (FlaC) Nup54 PF13874.1 CBZ49974.1 - 0.0057 16.3 3.2 0.0099 15.5 2.2 1.4 1 0 0 1 1 1 1 Nucleoporin complex subunit 54 NPV_P10 PF05531.7 CBZ49974.1 - 0.015 15.4 2.1 1.6 9.0 0.4 2.4 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein MtrG PF04210.8 CBZ49974.1 - 0.023 14.3 0.8 0.068 12.8 0.5 1.8 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit G Snapin_Pallidin PF14712.1 CBZ49974.1 - 0.023 15.0 0.9 0.042 14.1 0.6 1.4 1 0 0 1 1 1 0 Snapin/Pallidin ATG16 PF08614.6 CBZ49974.1 - 0.036 13.8 4.9 0.058 13.2 3.4 1.2 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) AAA_13 PF13166.1 CBZ49974.1 - 0.04 12.3 5.8 0.057 11.8 4.0 1.1 1 0 0 1 1 1 0 AAA domain Laminin_II PF06009.7 CBZ49974.1 - 0.047 13.4 8.5 0.056 13.1 4.5 1.9 1 1 1 2 2 2 0 Laminin Domain II Fib_alpha PF08702.5 CBZ49974.1 - 0.052 13.6 2.5 0.089 12.9 1.7 1.4 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family APG6 PF04111.7 CBZ49974.1 - 0.14 11.2 3.3 0.21 10.6 2.3 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 Prefoldin_2 PF01920.15 CBZ49974.1 - 0.21 11.3 8.7 2.1 8.1 1.0 2.3 1 1 1 2 2 2 0 Prefoldin subunit Phage_HK97_TLTM PF06120.6 CBZ49974.1 - 0.22 10.8 5.3 0.35 10.1 3.7 1.2 1 0 0 1 1 1 0 Tail length tape measure protein Med9 PF07544.8 CBZ49974.1 - 0.22 11.2 8.1 1.1 9.0 1.4 2.8 2 1 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 BBP1_C PF15272.1 CBZ49974.1 - 0.27 10.7 5.5 0.3 10.6 3.2 1.4 1 1 0 1 1 1 0 Spindle pole body component BBP1, C-terminal TBPIP PF07106.8 CBZ49974.1 - 0.29 10.6 6.3 0.54 9.7 3.7 1.8 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) BRE1 PF08647.6 CBZ49974.1 - 0.3 11.1 6.6 0.56 10.2 4.6 1.5 1 0 0 1 1 1 0 BRE1 E3 ubiquitin ligase Seryl_tRNA_N PF02403.17 CBZ49974.1 - 0.31 11.0 8.4 19 5.3 5.9 2.3 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain V_ATPase_I PF01496.14 CBZ49974.1 - 0.35 8.6 3.7 0.47 8.2 2.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family IncA PF04156.9 CBZ49974.1 - 0.41 10.2 7.0 1.6 8.3 4.9 1.8 1 1 0 1 1 1 0 IncA protein DUF2730 PF10805.3 CBZ49974.1 - 0.42 10.3 5.0 5.1 6.8 0.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2730) TMF_DNA_bd PF12329.3 CBZ49974.1 - 0.45 10.3 9.4 1.3 8.9 1.0 2.5 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Cytochrom_B562 PF07361.6 CBZ49974.1 - 0.6 10.5 5.6 0.9 9.9 2.5 2.1 1 1 1 2 2 2 0 Cytochrome b562 DUF1192 PF06698.6 CBZ49974.1 - 0.68 9.7 8.0 0.34 10.7 1.3 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF1192) Viral_P18 PF04521.8 CBZ49974.1 - 0.79 9.1 4.9 0.78 9.1 0.4 2.2 1 1 1 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein COG2 PF06148.6 CBZ49974.1 - 1.1 9.1 8.2 1.2 9.0 1.7 2.2 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 TPR_MLP1_2 PF07926.7 CBZ49974.1 - 1.2 8.9 8.7 4.9 6.9 6.0 1.8 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein DUF1090 PF06476.7 CBZ49974.1 - 1.7 8.3 8.3 3.7 7.2 5.8 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1090) Tropomyosin_1 PF12718.2 CBZ49974.1 - 2.1 8.2 13.3 6.2 6.6 9.2 1.7 1 1 0 1 1 1 0 Tropomyosin like DUF1664 PF07889.7 CBZ49974.1 - 2.6 7.8 5.6 6.1 6.6 3.7 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) DUF2570 PF10828.3 CBZ49974.1 - 4.2 7.0 5.6 17 5.0 1.4 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2570) DUF4407 PF14362.1 CBZ49974.1 - 4.4 6.1 10.1 6.5 5.6 7.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Spc7 PF08317.6 CBZ49974.1 - 9.3 4.8 9.7 29 3.1 6.1 1.8 1 1 0 1 1 1 0 Spc7 kinetochore protein SPC12 PF06645.8 CBZ49976.1 - 1e-20 73.2 0.4 1.5e-20 72.7 0.3 1.3 1 0 0 1 1 1 1 Microsomal signal peptidase 12 kDa subunit (SPC12) ABC2_membrane_3 PF12698.2 CBZ49976.1 - 0.039 12.9 0.9 0.041 12.9 0.6 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein Sec62 PF03839.11 CBZ49976.1 - 0.12 11.7 0.3 0.12 11.7 0.2 1.5 2 0 0 2 2 2 0 Translocation protein Sec62 AIF-MLS PF14962.1 CBZ49977.1 - 0.031 13.9 2.1 0.066 12.8 1.4 1.5 1 0 0 1 1 1 0 Mitochondria Localisation Sequence DUF4220 PF13968.1 CBZ49978.1 - 0.26 10.3 0.1 0.55 9.2 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4220) DUF106 PF01956.11 CBZ49978.1 - 3.8 7.0 2.1 46 3.5 0.1 2.3 2 0 0 2 2 2 0 Integral membrane protein DUF106 RRM_1 PF00076.17 CBZ49979.1 - 1.3e-33 114.4 0.0 4.9e-16 58.1 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBZ49979.1 - 2.4e-23 81.8 0.1 1.9e-10 40.5 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBZ49979.1 - 3.9e-15 55.4 0.1 3.7e-08 33.0 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM PF05172.8 CBZ49979.1 - 0.023 14.4 0.0 0.68 9.7 0.0 2.3 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif Nup35_RRM_2 PF14605.1 CBZ49979.1 - 0.039 13.7 0.1 2.3 8.0 0.0 2.4 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif RNA_bind PF08675.6 CBZ49979.1 - 0.044 13.7 0.0 0.13 12.2 0.0 1.8 2 0 0 2 2 2 0 RNA binding domain Nse4_C PF08743.5 CBZ49980.1 - 0.34 10.9 4.1 0.14 12.1 0.9 1.8 1 1 1 2 2 2 0 Nse4 C-terminal Adaptin_binding PF10199.4 CBZ49980.1 - 0.59 10.4 19.3 0.83 9.9 13.4 1.2 1 0 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 FAM60A PF15396.1 CBZ49980.1 - 2.6 7.7 9.0 3.3 7.3 6.2 1.2 1 0 0 1 1 1 0 Protein Family FAM60A DUF1510 PF07423.6 CBZ49980.1 - 3.3 7.0 24.9 4.4 6.6 17.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DUF2201_N PF13203.1 CBZ49980.1 - 9.6 5.2 19.0 12 4.9 13.2 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain DUF747 PF05346.6 CBZ49981.1 - 5.3e-105 351.1 0.0 7.4e-105 350.6 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic membrane protein family Dor1 PF04124.7 CBZ49981.1 - 0.03 12.7 0.1 0.048 12.1 0.1 1.2 1 0 0 1 1 1 0 Dor1-like family YhfT PF10797.4 CBZ49981.1 - 1.6 7.5 1.2 2.4 6.9 0.8 1.1 1 0 0 1 1 1 0 Protein of unknown function RimM PF01782.13 CBZ49982.1 - 3.7e-16 58.8 0.0 8.1e-16 57.7 0.0 1.6 1 0 0 1 1 1 1 RimM N-terminal domain zf-C2HC_2 PF13913.1 CBZ49982.1 - 0.013 15.1 1.9 0.022 14.4 1.3 1.4 1 0 0 1 1 1 0 zinc-finger of a C2HC-type Ribosomal_L35Ae PF01247.13 CBZ49982.1 - 0.014 15.1 0.0 1.7 8.4 0.0 2.4 2 0 0 2 2 2 0 Ribosomal protein L35Ae P19Arf_N PF07392.7 CBZ49982.1 - 0.019 15.1 0.2 0.15 12.2 0.0 2.2 2 0 0 2 2 2 0 Cyclin-dependent kinase inhibitor 2a p19Arf N-terminus zf-C2H2_4 PF13894.1 CBZ49982.1 - 0.028 14.7 2.5 0.066 13.5 1.8 1.7 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2 PF00096.21 CBZ49982.1 - 0.75 10.2 3.0 1.5 9.3 2.1 1.5 1 0 0 1 1 1 0 Zinc finger, C2H2 type APG12 PF04110.8 CBZ49983.1 - 2.2e-20 72.6 0.0 3.2e-20 72.0 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Prp18 PF02840.10 CBZ49984.1 - 8.2e-60 200.8 0.7 8.2e-60 200.8 0.5 2.2 2 0 0 2 2 2 1 Prp18 domain PRP4 PF08799.6 CBZ49984.1 - 4.7e-14 51.3 0.0 4.7e-14 51.3 0.0 2.1 3 0 0 3 3 3 1 pre-mRNA processing factor 4 (PRP4) like CDC37_N PF03234.9 CBZ49984.1 - 6.4 7.0 16.1 1.7 8.9 5.8 2.4 2 0 0 2 2 2 0 Cdc37 N terminal kinase binding Thr_synth_N PF14821.1 CBZ49986.1 - 1.9e-19 69.4 0.0 1.7e-18 66.3 0.0 2.3 2 0 0 2 2 2 1 Threonine synthase N terminus PALP PF00291.20 CBZ49986.1 - 6.8e-11 41.9 0.0 0.00017 20.9 0.0 2.4 2 0 0 2 2 2 2 Pyridoxal-phosphate dependent enzyme fn2 PF00040.14 CBZ49986.1 - 0.037 14.0 0.1 0.1 12.6 0.1 1.8 1 0 0 1 1 1 0 Fibronectin type II domain DEAD PF00270.24 CBZ49987.1 - 6.1e-32 110.4 0.0 1.9e-31 108.8 0.0 1.8 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CBZ49987.1 - 1.6e-20 72.7 0.3 5e-20 71.1 0.2 1.9 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 CBZ49987.1 - 4.9e-05 23.2 0.0 0.00014 21.7 0.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Dynactin_p22 PF07426.6 CBZ49989.1 - 0.0051 16.1 3.9 0.0073 15.6 2.7 1.6 1 1 0 1 1 1 1 Dynactin subunit p22 DUF2340 PF10209.4 CBZ49989.1 - 0.0064 16.6 0.9 0.024 14.7 0.4 2.0 1 1 1 2 2 2 1 Uncharacterized conserved protein (DUF2340) CorA PF01544.13 CBZ49989.1 - 0.016 14.2 6.5 0.049 12.6 3.4 1.9 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein Snapin_Pallidin PF14712.1 CBZ49989.1 - 0.027 14.7 0.7 0.1 12.9 0.2 2.2 1 1 1 2 2 2 0 Snapin/Pallidin Prominin PF05478.6 CBZ49989.1 - 0.059 10.9 2.0 0.06 10.8 1.4 1.1 1 0 0 1 1 1 0 Prominin Dynamitin PF04912.9 CBZ49989.1 - 0.061 12.1 6.4 0.68 8.6 4.5 2.3 1 1 0 1 1 1 0 Dynamitin Telomere_Sde2_2 PF13297.1 CBZ49989.1 - 0.068 12.4 1.0 1.2 8.4 0.1 2.5 2 0 0 2 2 2 0 Telomere stability C-terminal LexA_DNA_bind PF01726.11 CBZ49989.1 - 0.13 11.8 1.3 13 5.4 0.0 3.1 2 1 1 3 3 3 0 LexA DNA binding domain Iron_permease PF04120.7 CBZ49989.1 - 0.41 10.2 3.8 0.23 11.0 0.3 2.2 1 1 2 3 3 3 0 Low affinity iron permease MDMPI_C PF07398.6 CBZ49990.1 - 0.033 14.7 0.0 0.099 13.2 0.0 1.8 1 0 0 1 1 1 0 MDMPI C-terminal domain Pacs-1 PF10254.4 CBZ49991.1 - 3.1 6.3 5.1 5.9 5.4 3.5 1.4 1 0 0 1 1 1 0 PACS-1 cytosolic sorting protein HEAT PF02985.17 CBZ49992.1 - 9.8e-10 37.6 24.5 0.00023 20.9 0.0 7.8 9 0 0 9 9 9 4 HEAT repeat HEAT_2 PF13646.1 CBZ49992.1 - 5.1e-07 29.8 12.9 0.0012 19.0 1.0 4.8 2 1 1 4 4 4 3 HEAT repeats Adaptin_N PF01602.15 CBZ49992.1 - 0.044 12.1 3.2 0.23 9.7 0.1 3.0 3 1 0 3 3 3 0 Adaptin N terminal region Nop14 PF04147.7 CBZ49992.1 - 1.4 6.7 38.3 3.8 5.3 26.5 1.7 1 0 0 1 1 1 0 Nop14-like family SAPS PF04499.10 CBZ49992.1 - 4 5.9 15.2 10 4.5 10.5 1.6 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Telomere_reg-2 PF10193.4 CBZ49993.1 - 0.0022 18.2 0.0 0.0051 17.0 0.0 1.6 1 0 0 1 1 1 1 Telomere length regulation protein Choline_transpo PF04515.7 CBZ49994.1 - 1.9e-34 118.8 15.6 1.9e-34 118.8 10.8 2.1 2 0 0 2 2 2 1 Plasma-membrane choline transporter FtsJ PF01728.14 CBZ49995.1 - 1.6e-40 139.0 1.1 6.4e-39 133.8 0.8 2.2 1 1 0 1 1 1 1 FtsJ-like methyltransferase Acetyltransf_1 PF00583.19 CBZ49997.1 - 3.8e-08 33.2 0.1 1.1e-07 31.8 0.0 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_CG PF14542.1 CBZ49997.1 - 0.007 16.2 0.0 0.017 14.9 0.0 1.6 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase FR47 PF08445.5 CBZ49997.1 - 0.008 15.9 0.1 0.028 14.1 0.0 1.9 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 CBZ49997.1 - 0.011 15.8 0.0 0.026 14.6 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 CBZ49997.1 - 0.017 15.2 0.0 0.032 14.3 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 CBZ49997.1 - 0.062 13.4 0.0 0.24 11.5 0.0 2.0 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 CBZ49997.1 - 0.087 12.6 0.0 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Peptidase_M48 PF01435.13 CBZ49998.1 - 6.5e-50 169.7 0.0 1e-49 169.1 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M48 DUF1144 PF06610.8 CBZ49998.1 - 0.0059 16.3 0.0 0.012 15.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1144) NUDIX_2 PF13869.1 CBZ50000.1 - 1.7e-44 151.4 0.0 2.4e-44 150.9 0.0 1.2 1 0 0 1 1 1 1 Nucleotide hydrolase zf-CW PF07496.10 CBZ50001.1 - 5.1e-27 93.3 23.8 1.2e-15 56.9 4.1 2.7 2 0 0 2 2 2 2 CW-type Zinc Finger PHD PF00628.24 CBZ50001.1 - 0.023 14.3 5.9 0.3 10.8 1.3 2.7 2 0 0 2 2 2 0 PHD-finger Pro_isomerase PF00160.16 CBZ50002.1 - 2.1e-43 148.2 0.1 2.4e-43 148.0 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Motile_Sperm PF00635.21 CBZ50003.1 - 0.00018 21.1 0.0 0.045 13.3 0.0 2.9 2 1 0 2 2 2 2 MSP (Major sperm protein) domain PapD-like PF14874.1 CBZ50003.1 - 0.0063 16.4 0.2 0.43 10.5 0.0 2.8 2 0 0 2 2 2 1 Flagellar-associated PapD-like DSPc PF00782.15 CBZ50004.1 - 0.00033 20.2 0.2 0.00057 19.4 0.1 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 CBZ50004.1 - 0.00087 19.5 0.1 0.0083 16.3 0.0 2.5 2 1 0 2 2 2 1 Tyrosine phosphatase family DAHP_synth_2 PF01474.11 CBZ50006.1 - 2.5e-167 556.6 0.0 3e-167 556.4 0.0 1.1 1 0 0 1 1 1 1 Class-II DAHP synthetase family 2OG-FeII_Oxy_3 PF13640.1 CBZ50007.1 - 9.5e-07 29.2 0.1 2.7e-06 27.7 0.0 1.8 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 CBZ50007.1 - 4.2e-05 23.7 0.0 7.6e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 CBZ50007.1 - 0.0019 17.8 0.0 0.0047 16.5 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF3458 PF11940.3 CBZ50009.1 - 1e-46 159.4 0.5 1.3e-46 159.1 0.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3458) PBP1_TM PF14812.1 CBZ50009.1 - 0.28 11.5 6.2 0.099 12.9 1.1 2.2 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Carboxyl_trans PF01039.17 CBZ50010.1 - 2.9e-151 504.1 0.0 4.4e-151 503.5 0.0 1.3 1 0 0 1 1 1 1 Carboxyl transferase domain ACC_central PF08326.7 CBZ50010.1 - 1.5e-113 380.3 0.0 7.9e-107 358.1 0.0 2.1 2 0 0 2 2 2 2 Acetyl-CoA carboxylase, central region CPSase_L_D2 PF02786.12 CBZ50010.1 - 3.4e-50 170.2 0.0 6.1e-50 169.4 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_chain PF00289.17 CBZ50010.1 - 5.8e-26 90.7 0.0 1.4e-25 89.4 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 CBZ50010.1 - 1.4e-23 82.9 0.0 6.5e-21 74.3 0.0 2.7 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain ATP-grasp_4 PF13535.1 CBZ50010.1 - 1e-18 67.7 0.0 2.7e-18 66.3 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 CBZ50010.1 - 4.1e-12 45.4 0.0 8.1e-05 21.5 0.0 3.1 2 1 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon Biotin_lipoyl PF00364.17 CBZ50010.1 - 3.5e-11 42.5 0.2 8.9e-11 41.2 0.1 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.8 CBZ50010.1 - 7.7e-11 41.7 0.0 1.5e-10 40.8 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 CBZ50010.1 - 3.5e-09 36.2 0.0 9.2e-09 34.8 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.9 CBZ50010.1 - 6.2e-07 29.4 0.0 2.6e-06 27.4 0.0 2.1 2 0 0 2 2 2 1 ATP-grasp domain ATPgrasp_ST PF14397.1 CBZ50010.1 - 0.19 10.8 0.0 0.32 10.0 0.0 1.2 1 0 0 1 1 1 0 Sugar-transfer associated ATP-grasp RimK PF08443.6 CBZ50010.1 - 0.33 10.4 0.0 1.2 8.6 0.0 1.8 2 0 0 2 2 2 0 RimK-like ATP-grasp domain DNA_topoisoIV PF00521.15 CBZ50011.1 - 2.6e-126 421.9 0.0 3.4e-87 293.0 0.0 2.2 2 0 0 2 2 2 2 DNA gyrase/topoisomerase IV, subunit A DNA_gyraseA_C PF03989.8 CBZ50011.1 - 4.7e-21 73.8 7.8 3.3e-09 35.9 0.1 6.4 6 0 0 6 6 6 5 DNA gyrase C-terminal domain, beta-propeller DUF2457 PF10446.4 CBZ50011.1 - 3.8e-05 22.6 30.4 3.8e-05 22.6 21.1 3.5 4 0 0 4 4 4 1 Protein of unknown function (DUF2457) CDC73 PF05179.9 CBZ50011.1 - 1.1 8.6 8.3 2.9 7.1 5.7 1.7 1 0 0 1 1 1 0 RNA pol II accessory factor, Cdc73 family CRAL_TRIO PF00650.15 CBZ50012.1 - 3.2e-06 26.7 0.0 4.2e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain Ctr PF04145.10 CBZ50013.1 - 1.6e-21 76.8 0.5 5e-10 39.5 0.1 2.1 2 0 0 2 2 2 2 Ctr copper transporter family APG6 PF04111.7 CBZ50014.1 - 9.7e-67 225.2 0.1 4.2e-61 206.7 0.0 2.1 2 0 0 2 2 2 2 Autophagy protein Apg6 MerR_1 PF13411.1 CBZ50014.1 - 0.11 12.2 1.6 12 5.7 0.2 3.2 3 0 0 3 3 3 0 MerR HTH family regulatory protein Alba PF01918.16 CBZ50016.1 - 1.6e-18 66.0 0.5 2.4e-18 65.5 0.3 1.3 1 0 0 1 1 1 1 Alba Rpp20 PF12328.3 CBZ50016.1 - 8.6e-05 22.2 0.1 0.00011 21.8 0.1 1.2 1 0 0 1 1 1 1 Rpp20 subunit of nuclear RNase MRP and P zf-RING_UBOX PF13445.1 CBZ50017.1 - 0.009 15.7 0.4 0.028 14.1 0.3 1.9 1 0 0 1 1 1 1 RING-type zinc-finger FlaC_arch PF05377.6 CBZ50017.1 - 0.03 14.2 4.2 0.033 14.0 1.2 2.3 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) tRNA-synt_1e PF01406.14 CBZ50017.1 - 0.11 11.5 0.0 0.29 10.2 0.0 1.6 1 0 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain zf-RING_2 PF13639.1 CBZ50017.1 - 0.26 11.1 5.5 0.51 10.2 3.8 1.5 1 0 0 1 1 1 0 Ring finger domain TSC22 PF01166.13 CBZ50017.1 - 0.48 10.4 7.1 0.31 11.0 0.3 2.8 2 0 0 2 2 2 0 TSC-22/dip/bun family Cep57_CLD_2 PF14197.1 CBZ50017.1 - 0.97 9.4 18.1 0.88 9.5 4.2 3.6 3 0 0 3 3 3 0 Centrosome localisation domain of PPC89 Actin PF00022.14 CBZ50019.1 - 7.9e-41 139.7 0.0 1.3e-39 135.7 0.0 2.1 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.8 CBZ50019.1 - 8.8e-07 27.8 0.0 0.00035 19.2 0.0 2.1 2 0 0 2 2 2 2 MreB/Mbl protein Kinesin PF00225.18 CBZ50020.1 - 5.2e-103 344.2 0.0 5.2e-103 344.2 0.0 2.3 3 0 0 3 3 3 1 Kinesin motor domain KIF1B PF12423.3 CBZ50020.1 - 9.5e-11 41.5 0.5 5.8e-10 39.0 0.0 2.6 3 0 0 3 3 3 1 Kinesin protein 1B FHA PF00498.21 CBZ50020.1 - 1.9e-07 31.1 0.0 9.4e-07 28.8 0.0 2.2 2 0 0 2 2 2 1 FHA domain SYF2 PF08231.7 CBZ50020.1 - 0.0024 18.0 19.2 0.16 12.0 7.9 2.5 2 0 0 2 2 2 2 SYF2 splicing factor OmpH PF03938.9 CBZ50020.1 - 0.0031 17.4 30.9 0.07 13.0 3.1 2.5 2 0 0 2 2 2 2 Outer membrane protein (OmpH-like) Sdh5 PF03937.11 CBZ50021.1 - 0.75 9.5 5.6 0.077 12.6 0.5 1.8 2 0 0 2 2 2 0 Flavinator of succinate dehydrogenase SPRY PF00622.23 CBZ50023.1 - 3.1e-09 36.9 0.0 0.00017 21.6 0.0 2.4 2 0 0 2 2 2 2 SPRY domain His_Phos_1 PF00300.17 CBZ50024.1 - 1.4e-12 47.9 0.0 6.7e-08 32.7 0.0 3.3 2 1 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) Thionin PF00321.12 CBZ50024.1 - 0.05 13.8 0.3 0.12 12.5 0.2 1.6 1 0 0 1 1 1 0 Plant thionin PUA PF01472.15 CBZ50026.1 - 1.8e-15 56.3 0.0 2.8e-15 55.8 0.0 1.3 1 0 0 1 1 1 1 PUA domain BSD PF03909.12 CBZ50026.1 - 0.056 13.1 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 BSD domain DSPc PF00782.15 CBZ50027.1 - 1.3e-21 76.5 0.0 1.2e-19 70.2 0.0 2.2 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 CBZ50027.1 - 0.012 14.9 0.0 0.018 14.3 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Adap_comp_sub PF00928.16 CBZ50029.1 - 5.6e-08 32.2 0.0 1.9e-07 30.4 0.0 1.7 1 1 0 1 1 1 1 Adaptor complexes medium subunit family DUSP PF06337.7 CBZ50031.1 - 1.7e-05 25.1 0.0 3.9e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 DUSP domain zf-C2HC_2 PF13913.1 CBZ50031.1 - 0.0061 16.1 0.6 0.019 14.6 0.1 2.1 2 0 0 2 2 2 1 zinc-finger of a C2HC-type MORN PF02493.15 CBZ50031.1 - 0.023 14.3 10.5 0.11 12.2 0.3 4.1 4 0 0 4 4 4 0 MORN repeat Pkinase PF00069.20 CBZ50032.1 - 0.025 13.7 0.0 0.045 12.9 0.0 1.3 1 0 0 1 1 1 0 Protein kinase domain LRRCT PF01463.19 CBZ50032.1 - 0.39 11.1 2.1 1.2 9.6 1.4 1.9 1 0 0 1 1 1 0 Leucine rich repeat C-terminal domain RRM_6 PF14259.1 CBZ50034.1 - 0.0023 17.8 0.0 0.0089 15.9 0.0 2.0 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CBZ50034.1 - 0.016 14.8 0.0 0.17 11.5 0.0 2.2 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FtsJ PF01728.14 CBZ50035.1 - 6.3e-17 62.1 0.0 3.1e-13 50.1 0.0 2.3 2 0 0 2 2 2 2 FtsJ-like methyltransferase RAP1 PF07218.6 CBZ50035.1 - 0.022 12.9 3.0 0.04 12.0 2.1 1.3 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) SNF PF00209.13 CBZ50035.1 - 0.85 8.0 0.0 1.2 7.4 0.0 1.1 1 0 0 1 1 1 0 Sodium:neurotransmitter symporter family DSPc PF00782.15 CBZ50036.1 - 1.3e-20 73.3 0.0 1.7e-20 72.9 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 CBZ50036.1 - 0.0036 16.6 0.0 0.0049 16.2 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase CDKN3 PF05706.7 CBZ50036.1 - 0.026 13.9 0.1 0.041 13.3 0.1 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) Oligomerisation PF02410.10 CBZ50037.1 - 2e-13 50.2 0.0 3.4e-13 49.4 0.0 1.4 1 0 0 1 1 1 1 Oligomerisation domain UCH PF00443.24 CBZ50038.1 - 2.5e-26 92.3 0.0 8e-26 90.7 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CBZ50038.1 - 8.1e-07 28.7 0.0 0.0028 17.1 0.0 2.2 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Tubulin PF00091.20 CBZ50039.1 - 1.3e-70 237.6 0.0 2e-70 236.9 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 CBZ50039.1 - 2.1e-49 166.7 0.1 3.2e-49 166.1 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 CBZ50039.1 - 4.3e-05 23.5 0.0 0.0001 22.3 0.0 1.6 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.1 CBZ50039.1 - 0.006 16.0 0.0 0.013 15.0 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain DUF456 PF04306.8 CBZ50041.1 - 0.0059 16.6 0.6 0.01 15.9 0.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF456) Bacteriocin_IIc PF10439.4 CBZ50041.1 - 7.3 6.7 23.9 21 5.3 16.6 1.7 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide DEAD PF00270.24 CBZ50042.1 - 3.6e-36 124.2 0.0 1.2e-35 122.5 0.0 2.0 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CBZ50042.1 - 4.1e-21 74.6 0.1 9.5e-21 73.4 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Corona_NS1 PF06145.6 CBZ50042.1 - 0.15 11.3 1.4 0.3 10.4 0.9 1.5 1 0 0 1 1 1 0 Coronavirus nonstructural protein NS1 SPT16 PF08644.6 CBZ50043.1 - 9.7e-39 132.6 0.1 9.7e-39 132.6 0.0 4.1 3 2 0 3 3 3 1 FACT complex subunit (SPT16/CDC68) Rtt106 PF08512.7 CBZ50043.1 - 1.9e-19 69.4 0.2 5.8e-18 64.6 0.0 3.0 3 0 0 3 3 3 1 Histone chaperone Rttp106-like Peptidase_M24 PF00557.19 CBZ50043.1 - 1.2e-10 41.3 0.0 2.4e-10 40.3 0.0 1.5 1 0 0 1 1 1 1 Metallopeptidase family M24 FACT-Spt16_Nlob PF14826.1 CBZ50044.1 - 4.2e-20 71.8 0.0 1.2e-19 70.4 0.0 1.8 1 0 0 1 1 1 1 FACT complex subunit SPT16 N-terminal lobe domain DUF846 PF05832.7 CBZ50046.1 - 2.1e-42 144.1 11.2 2.8e-42 143.7 7.8 1.2 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) RabGAP-TBC PF00566.13 CBZ50048.1 - 1.1e-40 139.3 0.6 1.1e-40 139.3 0.4 2.6 3 0 0 3 3 3 1 Rab-GTPase-TBC domain Peptidase_S8 PF00082.17 CBZ50049.1 - 2.4e-47 161.4 0.9 3.7e-47 160.8 0.6 1.3 1 0 0 1 1 1 1 Subtilase family PAN_1 PF00024.21 CBZ50049.1 - 3.8e-05 23.3 0.0 8.1e-05 22.2 0.0 1.5 1 0 0 1 1 1 1 PAN domain SDA1 PF05285.7 CBZ50049.1 - 0.0012 18.2 3.1 0.004 16.4 2.1 1.7 1 1 0 1 1 1 1 SDA1 DUF3251 PF11622.3 CBZ50049.1 - 0.076 12.4 0.0 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3251) Ribosomal_S17 PF00366.15 CBZ50049.1 - 0.16 12.0 0.0 0.33 11.0 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein S17 PAN_2 PF08276.6 CBZ50049.1 - 0.36 10.7 0.0 0.74 9.7 0.0 1.5 1 0 0 1 1 1 0 PAN-like domain Band_7 PF01145.20 CBZ50051.1 - 2.6e-08 33.9 0.4 3.2e-08 33.6 0.3 1.0 1 0 0 1 1 1 1 SPFH domain / Band 7 family WD40 PF00400.27 CBZ50053.1 - 3.7e-17 61.4 19.9 4.6e-05 23.1 0.1 9.9 10 1 1 11 11 11 4 WD domain, G-beta repeat EF-hand_8 PF13833.1 CBZ50053.1 - 0.039 13.5 0.0 0.24 11.0 0.0 2.2 2 0 0 2 2 2 0 EF-hand domain pair EF-hand_1 PF00036.27 CBZ50053.1 - 0.046 13.0 0.0 0.27 10.6 0.0 2.2 2 0 0 2 2 2 0 EF hand EF-hand_6 PF13405.1 CBZ50053.1 - 0.061 13.2 0.0 0.2 11.5 0.0 1.9 1 0 0 1 1 1 0 EF-hand domain EF-hand_7 PF13499.1 CBZ50053.1 - 0.077 13.1 0.1 0.59 10.3 0.0 2.3 2 0 0 2 2 2 0 EF-hand domain pair zf-A20 PF01754.11 CBZ50055.1 - 7.5e-12 44.5 6.3 7.5e-12 44.5 4.4 2.1 2 0 0 2 2 2 1 A20-like zinc finger zf-AN1 PF01428.11 CBZ50055.1 - 1.4e-11 44.0 7.5 1.4e-11 44.0 5.2 1.9 2 0 0 2 2 2 1 AN1-like Zinc finger DUF4428 PF14471.1 CBZ50055.1 - 0.0049 16.5 3.4 1.5 8.6 1.3 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF4428) Methyltransf_11 PF08241.7 CBZ50056.1 - 4.1e-07 30.4 0.0 5.3e-06 26.8 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CBZ50056.1 - 0.0014 19.1 0.0 0.0025 18.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CBZ50056.1 - 0.0054 17.1 0.0 0.016 15.6 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CBZ50056.1 - 0.0076 15.8 0.0 3 7.4 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.1 CBZ50056.1 - 0.019 14.6 0.0 0.051 13.3 0.0 1.7 2 1 0 2 2 2 0 Methyltransferase domain TPMT PF05724.6 CBZ50056.1 - 0.048 13.0 0.0 0.11 11.9 0.0 1.5 1 1 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) Methyltransf_25 PF13649.1 CBZ50056.1 - 0.15 12.4 0.0 0.39 11.1 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain NifU PF01106.12 CBZ50057.1 - 3.3e-19 68.4 0.0 1.3e-15 56.8 0.0 2.6 2 1 0 2 2 2 2 NifU-like domain DUF1720 PF08226.6 CBZ50058.1 - 0.12 12.4 0.1 0.21 11.6 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1720) Adaptin_N PF01602.15 CBZ50059.1 - 9e-55 185.9 0.0 7.7e-49 166.4 0.0 2.8 2 1 0 2 2 2 2 Adaptin N terminal region HEAT_2 PF13646.1 CBZ50059.1 - 0.00028 21.0 0.8 0.00028 21.0 0.6 4.4 5 1 0 5 5 5 1 HEAT repeats Arm PF00514.18 CBZ50059.1 - 0.091 12.6 0.6 0.66 9.9 0.0 2.8 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat Alpha_adaptin_C PF02296.11 CBZ50059.1 - 0.16 11.9 0.0 0.45 10.4 0.0 1.8 2 0 0 2 2 2 0 Alpha adaptin AP2, C-terminal domain DUF3449 PF11931.3 CBZ50060.1 - 3.4e-75 251.8 1.3 7e-75 250.8 0.9 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3449) SF3a60_bindingd PF12108.3 CBZ50060.1 - 2e-08 33.6 0.3 8.2e-08 31.6 0.1 2.2 2 0 0 2 2 2 1 Splicing factor SF3a60 binding domain Desulfoferrod_N PF06397.7 CBZ50060.1 - 0.11 11.8 0.2 0.2 11.0 0.2 1.4 1 0 0 1 1 1 0 Desulfoferrodoxin, N-terminal domain DUF2423 PF10338.4 CBZ50061.1 - 4.6e-12 45.6 0.6 1.2e-11 44.3 0.4 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2423) WW PF00397.21 CBZ50062.1 - 5e-08 32.6 0.1 1.6e-07 31.0 0.0 1.9 1 0 0 1 1 1 1 WW domain zf-U1 PF06220.7 CBZ50062.1 - 2.4e-05 23.7 1.4 5.1e-05 22.7 1.0 1.6 1 0 0 1 1 1 1 U1 zinc finger DUF2246 PF10229.4 CBZ50062.1 - 0.00021 20.6 0.3 0.00047 19.5 0.2 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2246) AKAP95 PF04988.7 CBZ50062.1 - 0.062 13.0 0.6 0.1 12.3 0.4 1.2 1 0 0 1 1 1 0 A-kinase anchoring protein 95 (AKAP95) Brix PF04427.13 CBZ50064.1 - 8.9e-34 116.8 0.0 1.2e-33 116.3 0.0 1.2 1 0 0 1 1 1 1 Brix domain BSP_II PF05432.6 CBZ50064.1 - 0.018 14.3 33.7 0.026 13.8 23.3 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) NIF PF03031.13 CBZ50065.1 - 7.6e-25 87.4 0.2 1.1e-24 86.9 0.2 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase RR_TM4-6 PF06459.7 CBZ50065.1 - 0.13 12.1 1.5 0.28 11.0 1.1 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 PGK PF00162.14 CBZ50066.1 - 9e-150 498.4 0.0 1.1e-149 498.1 0.0 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase TMP-TENI PF02581.12 CBZ50066.1 - 0.025 13.7 0.1 0.059 12.4 0.1 1.6 1 0 0 1 1 1 0 Thiamine monophosphate synthase/TENI DOT1 PF08123.8 CBZ50067.1 - 0.0029 16.9 0.0 0.0046 16.2 0.0 1.2 1 0 0 1 1 1 1 Histone methylation protein DOT1 Mog1 PF04603.7 CBZ50068.1 - 3.2e-29 101.6 0.0 5e-29 101.0 0.0 1.2 1 0 0 1 1 1 1 Ran-interacting Mog1 protein Ion_trans PF00520.26 CBZ50070.1 - 6.3e-16 58.2 30.6 6.3e-16 58.2 21.2 1.5 2 0 0 2 2 2 1 Ion transport protein GTP_EFTU PF00009.22 CBZ50071.1 - 1.4e-38 132.2 0.0 2e-38 131.7 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 CBZ50071.1 - 4.3e-06 26.8 0.2 9e-06 25.7 0.2 1.5 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain MMR_HSR1 PF01926.18 CBZ50071.1 - 6.6e-05 22.8 0.0 0.00027 20.8 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 CBZ50071.1 - 0.0034 17.8 0.0 1.3 9.5 0.2 2.4 1 1 1 2 2 2 2 Miro-like protein GTP_EFTU_D2 PF03144.20 CBZ50071.1 - 0.026 14.6 0.3 0.12 12.5 0.0 2.2 2 0 0 2 2 2 0 Elongation factor Tu domain 2 SRPRB PF09439.5 CBZ50071.1 - 0.09 11.9 0.0 2.8 7.1 0.0 2.2 1 1 1 2 2 2 0 Signal recognition particle receptor beta subunit Septin PF00735.13 CBZ50071.1 - 0.25 10.3 0.0 0.4 9.6 0.0 1.2 1 0 0 1 1 1 0 Septin Rab5ip PF07019.7 CBZ50073.1 - 9.8e-11 41.6 7.8 1.6e-10 40.9 5.4 1.3 1 0 0 1 1 1 1 Rab5-interacting protein (Rab5ip) DUF2613 PF11021.3 CBZ50073.1 - 4.3 7.1 7.9 1.1 9.0 3.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2613) VHS PF00790.14 CBZ50074.1 - 0.071 12.7 0.0 0.16 11.5 0.0 1.5 1 0 0 1 1 1 0 VHS domain Ribonuc_red_lgN PF00317.16 CBZ50074.1 - 0.16 11.7 0.0 0.33 10.7 0.0 1.5 1 0 0 1 1 1 0 Ribonucleotide reductase, all-alpha domain PUB PF09409.5 CBZ50075.1 - 2.6e-15 55.9 0.0 7e-15 54.5 0.0 1.8 1 0 0 1 1 1 1 PUB domain UBA PF00627.26 CBZ50075.1 - 7.8e-06 25.5 0.2 0.00016 21.3 0.2 2.7 1 1 0 1 1 1 1 UBA/TS-N domain Asp-B-Hydro_N PF05279.6 CBZ50075.1 - 0.78 9.5 21.5 1.2 8.9 14.9 1.3 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region V_ATPase_I PF01496.14 CBZ50075.1 - 2.1 6.1 9.9 2.5 5.8 6.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Spore_coat_CotO PF14153.1 CBZ50075.1 - 3.2 7.1 20.7 9.1 5.6 14.3 1.8 1 1 0 1 1 1 0 Spore coat protein CotO AAA_23 PF13476.1 CBZ50075.1 - 7.2 6.8 13.8 2.5 8.3 7.8 1.6 2 0 0 2 2 2 0 AAA domain DUF1985 PF09331.6 CBZ50075.1 - 9.2 6.0 8.7 0.45 10.3 1.3 2.1 1 1 2 3 3 3 0 Domain of unknown function (DUF1985) PseudoU_synth_2 PF00849.17 CBZ50076.1 - 0.00087 19.1 0.0 0.044 13.6 0.0 2.4 2 0 0 2 2 2 2 RNA pseudouridylate synthase RNHCP PF12647.2 CBZ50077.1 - 0.0012 18.5 0.4 1.4 8.8 0.0 3.1 3 0 0 3 3 3 1 RNHCP domain Nudix_N_2 PF14803.1 CBZ50077.1 - 0.0022 17.6 5.3 1.2 8.9 0.0 3.4 3 0 0 3 3 3 2 Nudix N-terminal GFA PF04828.9 CBZ50077.1 - 0.026 14.4 2.8 0.39 10.6 0.2 2.5 1 1 0 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme UPF0167 PF03691.9 CBZ50077.1 - 0.033 13.5 0.1 1.5 8.2 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0167) DNA_RNApol_7kD PF03604.8 CBZ50077.1 - 0.13 11.7 6.4 15 5.1 0.1 3.4 3 0 0 3 3 3 0 DNA directed RNA polymerase, 7 kDa subunit Yippee-Mis18 PF03226.9 CBZ50077.1 - 0.14 12.2 1.1 0.2 11.7 0.1 1.8 2 1 0 2 2 2 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly OrfB_Zn_ribbon PF07282.6 CBZ50077.1 - 0.77 9.4 3.4 8.5 6.1 0.1 3.0 3 0 0 3 3 3 0 Putative transposase DNA-binding domain Rpr2 PF04032.11 CBZ50077.1 - 0.83 9.5 4.5 0.59 10.0 1.3 2.0 2 1 0 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain DEAD PF00270.24 CBZ50078.1 - 1.6e-36 125.3 0.0 2.2e-17 63.0 0.0 3.2 3 0 0 3 3 3 2 DEAD/DEAH box helicase Helicase_C PF00271.26 CBZ50078.1 - 1.3e-19 69.8 0.1 4.2e-12 45.7 0.0 2.9 3 0 0 3 3 3 2 Helicase conserved C-terminal domain GUCT PF08152.7 CBZ50078.1 - 0.0083 16.0 0.0 0.018 15.0 0.0 1.5 1 0 0 1 1 1 1 GUCT (NUC152) domain DUF1253 PF06862.7 CBZ50078.1 - 0.22 9.8 0.0 4.6 5.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1253) Aldedh PF00171.17 CBZ50079.1 - 3.3e-178 592.7 0.0 3.7e-178 592.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 CBZ50079.1 - 0.00049 19.3 0.1 0.0037 16.5 0.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF1487) Ribosomal_L36 PF00444.13 CBZ50081.1 - 0.0001 22.2 0.1 0.0001 22.2 0.1 2.0 2 0 0 2 2 2 1 Ribosomal protein L36 DUF384 PF04064.8 CBZ50083.1 - 1.4e-13 50.2 1.6 1.9e-13 49.7 0.3 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF384) DUF383 PF04063.9 CBZ50083.1 - 0.033 13.7 0.0 0.15 11.6 0.0 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF383) LMBR1 PF04791.11 CBZ50084.1 - 3.1e-22 78.8 17.1 6.2e-21 74.5 11.8 2.1 1 1 0 1 1 1 1 LMBR1-like membrane protein Band_7 PF01145.20 CBZ50085.1 - 1.1e-31 110.1 0.1 1.6e-31 109.6 0.1 1.2 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.1 CBZ50085.1 - 0.01 15.3 0.0 0.045 13.2 0.0 2.0 2 1 1 3 3 3 0 SPFH domain-Band 7 family META PF03724.11 CBZ50085.1 - 0.06 13.1 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 META domain IMCp PF12314.3 CBZ50086.1 - 7.8 6.7 11.0 1.3 9.2 4.4 2.2 2 0 0 2 2 2 0 Inner membrane complex protein MMS19_N PF14500.1 CBZ50087.1 - 1.1e-31 110.1 0.5 3.2e-29 101.9 0.0 2.9 3 0 0 3 3 3 2 Dos2-interacting transcription regulator of RNA-Pol-II NhaB PF06450.7 CBZ50087.1 - 0.16 10.5 0.0 0.27 9.8 0.0 1.2 1 0 0 1 1 1 0 Bacterial Na+/H+ antiporter B (NhaB) FHA PF00498.21 CBZ50089.1 - 0.003 17.6 0.1 0.28 11.3 0.0 3.1 3 1 0 3 3 3 1 FHA domain RDD PF06271.7 CBZ50090.1 - 0.17 11.7 2.7 0.22 11.4 1.8 1.2 1 0 0 1 1 1 0 RDD family DUF2568 PF10823.3 CBZ50090.1 - 0.62 10.3 5.9 5.4 7.3 4.5 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2568) DUF4282 PF14110.1 CBZ50090.1 - 2.2 8.5 5.5 3.1 8.0 3.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4282) DUF1601 PF07671.6 CBZ50092.1 - 0.093 12.3 0.0 0.71 9.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1601) LSM PF01423.17 CBZ50093.1 - 6.5e-11 41.6 0.2 1e-10 40.9 0.1 1.3 1 0 0 1 1 1 1 LSM domain DUF1084 PF06454.6 CBZ50095.1 - 2.7e-09 36.5 3.3 4.1e-09 35.8 2.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1084) DUF1129 PF06570.6 CBZ50095.1 - 0.0074 15.6 0.2 0.016 14.5 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1129) DUF1469 PF07332.6 CBZ50095.1 - 0.017 14.8 1.9 0.017 14.8 1.3 2.9 4 0 0 4 4 4 0 Protein of unknown function (DUF1469) Nol1_Nop2_Fmu PF01189.12 CBZ50097.1 - 1.7e-15 57.1 0.0 4.1e-08 32.9 0.0 2.2 2 0 0 2 2 2 2 NOL1/NOP2/sun family FtsJ PF01728.14 CBZ50097.1 - 0.0009 19.2 0.0 0.0015 18.5 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Spc97_Spc98 PF04130.8 CBZ50098.1 - 0.045 12.0 0.2 0.11 10.7 0.0 1.5 1 1 0 1 1 1 0 Spc97 / Spc98 family Fer2_3 PF13085.1 CBZ50098.1 - 0.088 12.6 0.1 0.28 11.0 0.0 1.9 2 0 0 2 2 2 0 2Fe-2S iron-sulfur cluster binding domain Baculo_PEP_C PF04513.7 CBZ50098.1 - 0.49 10.2 2.4 18 5.1 0.2 2.6 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF2042 PF09743.4 CBZ50099.1 - 1.2e-72 244.5 0.0 1.6e-72 244.1 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2042) FeoC PF09012.5 CBZ50099.1 - 7.6e-06 25.5 1.6 2.7 7.7 0.0 4.7 5 0 0 5 5 5 2 FeoC like transcriptional regulator HTH_9 PF08221.6 CBZ50099.1 - 0.00038 20.2 0.2 1.2 9.1 0.0 3.0 3 0 0 3 3 3 2 RNA polymerase III subunit RPC82 helix-turn-helix domain PCI PF01399.22 CBZ50099.1 - 0.0045 17.2 0.1 0.052 13.8 0.0 2.6 2 1 0 2 2 2 1 PCI domain HTH_DeoR PF08220.7 CBZ50099.1 - 0.025 14.1 0.1 6.5 6.3 0.0 2.7 2 0 0 2 2 2 0 DeoR-like helix-turn-helix domain Rrf2 PF02082.15 CBZ50099.1 - 0.041 13.9 1.3 23 5.1 0.0 3.8 4 0 0 4 4 4 0 Transcriptional regulator URO-D PF01208.12 CBZ50099.1 - 0.045 12.6 0.0 0.083 11.7 0.0 1.3 1 0 0 1 1 1 0 Uroporphyrinogen decarboxylase (URO-D) FolB PF02152.13 CBZ50099.1 - 0.05 13.7 0.8 1.6 8.8 0.1 2.6 2 0 0 2 2 2 0 Dihydroneopterin aldolase SAG PF04092.8 CBZ50100.1 - 4.3e-12 46.5 0.4 1.5e-06 28.6 0.0 3.7 3 1 0 3 3 3 3 SRS domain IBN_N PF03810.14 CBZ50101.1 - 2e-06 27.6 0.4 8.4e-06 25.6 0.3 2.2 1 0 0 1 1 1 1 Importin-beta N-terminal domain LMF1 PF06762.9 CBZ50104.1 - 4.7e-77 259.3 0.4 7.1e-77 258.7 0.3 1.2 1 0 0 1 1 1 1 Lipase maturation factor DoxX PF07681.7 CBZ50104.1 - 1.3e-07 31.9 1.1 5.6e-07 29.9 0.8 2.2 1 0 0 1 1 1 1 DoxX HECT PF00632.20 CBZ50106.1 - 1.8e-70 237.6 0.0 3.1e-70 236.8 0.0 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) RCC1 PF00415.13 CBZ50106.1 - 9.5e-37 124.9 16.9 7.3e-12 45.3 0.1 9.7 10 1 0 10 10 10 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 CBZ50106.1 - 2.5e-31 106.5 27.6 7.7e-09 34.9 0.1 7.5 7 0 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat LRR_4 PF12799.2 CBZ50107.1 - 5.2e-17 61.0 8.8 5.2e-09 35.5 0.0 4.7 3 1 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CBZ50107.1 - 2e-14 53.0 9.6 1.2e-06 28.1 2.2 3.9 4 0 0 4 4 4 2 Leucine rich repeat LRR_1 PF00560.28 CBZ50107.1 - 8.9e-06 25.0 7.2 6.1 7.2 0.0 6.7 6 1 1 7 7 7 1 Leucine Rich Repeat LRR_6 PF13516.1 CBZ50107.1 - 1.7e-05 24.4 5.2 4.7 7.5 0.1 5.6 5 0 0 5 5 5 3 Leucine Rich repeat LRR_7 PF13504.1 CBZ50107.1 - 0.047 13.8 9.5 21 5.8 0.2 6.0 7 0 0 7 7 7 0 Leucine rich repeat DUF2920 PF11144.3 CBZ50107.1 - 0.41 9.6 0.0 0.68 8.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2920) ISN1 PF06437.6 CBZ50110.1 - 1.1e-89 300.9 0.0 1.5e-89 300.5 0.0 1.1 1 0 0 1 1 1 1 IMP-specific 5'-nucleotidase Glyco_transf_5 PF08323.6 CBZ50111.1 - 7.3e-34 117.3 0.0 1.2e-33 116.6 0.0 1.3 1 0 0 1 1 1 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.15 CBZ50111.1 - 5.8e-14 51.8 0.0 1e-13 51.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Codanin-1_C PF15296.1 CBZ50111.1 - 0.11 12.3 3.8 0.13 12.1 0.8 2.5 2 0 0 2 2 2 0 Codanin-1 C-terminus Guanylate_cyc PF00211.15 CBZ50111.1 - 0.71 9.2 0.1 3.9 6.7 0.0 2.0 2 0 0 2 2 2 0 Adenylate and Guanylate cyclase catalytic domain DUF2827 PF10933.3 CBZ50111.1 - 2.3 6.6 0.0 3.9 5.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2827) Alpha-amylase PF00128.19 CBZ50111.1 - 5.3 6.3 0.0 56 2.9 0.0 2.2 2 0 0 2 2 2 0 Alpha amylase, catalytic domain Metallophos_2 PF12850.2 CBZ50112.1 - 4e-07 29.9 0.0 6.1e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 CBZ50112.1 - 7.2e-07 28.7 0.6 4.4e-06 26.2 0.4 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Dabb PF07876.7 CBZ50113.1 - 6.5e-19 68.1 0.3 7.1e-19 68.0 0.2 1.0 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain eIF2A PF08662.6 CBZ50114.1 - 1.3e-30 106.5 5.8 6.1e-25 88.0 0.6 3.1 3 2 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A RRM_1 PF00076.17 CBZ50114.1 - 4.5e-06 26.2 0.0 2.3e-05 23.9 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBZ50114.1 - 0.0025 17.6 0.0 0.0059 16.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.27 CBZ50114.1 - 0.0064 16.3 0.0 53 3.9 0.0 4.5 4 0 0 4 4 4 0 WD domain, G-beta repeat RRM_6 PF14259.1 CBZ50114.1 - 0.013 15.4 0.0 0.05 13.5 0.0 2.0 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF2372 PF10178.4 CBZ50115.1 - 8.6e-06 25.8 0.0 1.6e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2372) DUF668 PF05003.7 CBZ50116.1 - 0.044 13.9 0.1 0.53 10.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF668) FliE PF02049.13 CBZ50116.1 - 0.14 12.1 3.5 0.1 12.6 0.2 2.2 2 0 0 2 2 2 0 Flagellar hook-basal body complex protein FliE HAD PF12710.2 CBZ50117.1 - 3.7e-16 59.8 0.0 1.7e-12 47.9 0.0 2.5 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 CBZ50117.1 - 4e-10 40.4 15.9 7.6e-10 39.5 0.1 4.0 2 2 0 2 2 2 1 haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.7 CBZ50117.1 - 2.3e-07 30.2 0.0 3.3e-06 26.4 0.0 2.3 1 1 0 1 1 1 1 Putative Phosphatase Hydrolase_3 PF08282.7 CBZ50117.1 - 4.2e-07 29.8 0.2 9.7e-07 28.6 0.0 1.5 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase ACT_6 PF13740.1 CBZ50117.1 - 0.00026 20.6 0.1 3.8 7.3 0.0 4.6 5 0 0 5 5 5 2 ACT domain HAD_2 PF13419.1 CBZ50117.1 - 0.0018 18.5 2.4 0.0021 18.2 0.0 2.4 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase DUF705 PF05152.7 CBZ50117.1 - 0.6 9.0 0.0 0.99 8.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF705) His_Phos_1 PF00300.17 CBZ50118.1 - 6.2e-18 65.3 0.0 1e-17 64.6 0.0 1.4 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) His_Phos_2 PF00328.17 CBZ50118.1 - 0.17 11.1 0.1 0.25 10.6 0.0 1.2 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 2) Sedlin_N PF04628.8 CBZ50119.1 - 2.3e-37 127.7 0.0 2.7e-37 127.6 0.0 1.0 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.7 CBZ50119.1 - 2.4e-05 24.0 0.0 8.2e-05 22.3 0.0 1.8 1 1 0 1 1 1 1 Sybindin-like family LRV_FeS PF05484.6 CBZ50119.1 - 0.061 12.9 0.0 0.091 12.3 0.0 1.3 1 0 0 1 1 1 0 LRV protein FeS4 cluster DUF814 PF05670.8 CBZ50120.1 - 7.2e-18 64.2 0.0 1.4e-17 63.3 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF814) Helicase_RecD PF05127.9 CBZ50120.1 - 0.086 12.4 0.4 0.14 11.7 0.3 1.3 1 0 0 1 1 1 0 Helicase CPW_WPC PF09717.5 CBZ50121.1 - 0.039 14.5 3.8 0.099 13.2 0.1 2.9 2 1 0 2 2 2 0 Plasmodium falciparum domain of unknown function (CPW_WPC) DUF35_N PF12172.3 CBZ50121.1 - 0.84 9.6 6.5 0.96 9.4 0.6 3.1 2 1 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) Ocnus PF05005.10 CBZ50122.1 - 6e-24 83.9 0.4 9.2e-24 83.3 0.3 1.3 1 0 0 1 1 1 1 Janus/Ocnus family (Ocnus) Pkinase PF00069.20 CBZ50123.1 - 9.1e-18 64.3 0.0 4.5e-17 62.0 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ50123.1 - 1.8e-06 27.2 0.0 8.3e-06 25.0 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Inositol_P PF00459.20 CBZ50124.1 - 2.3e-59 200.9 0.4 1.1e-58 198.6 0.3 1.9 1 1 0 1 1 1 1 Inositol monophosphatase family PAN_1 PF00024.21 CBZ50125.1 - 8e-20 70.3 12.6 1.7e-05 24.4 0.0 4.5 4 0 0 4 4 4 4 PAN domain PAN_4 PF14295.1 CBZ50125.1 - 1.2e-16 60.0 24.2 0.00025 20.7 0.3 4.6 4 0 0 4 4 4 4 PAN domain PAN_2 PF08276.6 CBZ50125.1 - 0.026 14.3 0.3 0.026 14.3 0.2 4.2 4 0 0 4 4 4 0 PAN-like domain Ribosomal_S18 PF01084.15 CBZ50126.1 - 5.6e-14 51.7 0.0 2.5e-13 49.6 0.0 2.1 3 0 0 3 3 3 1 Ribosomal protein S18 Dynein_light PF01221.13 CBZ50127.1 - 2.4e-44 149.2 0.5 2.6e-44 149.0 0.3 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 Imm28 PF15574.1 CBZ50127.1 - 0.12 11.9 0.1 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 Immunity protein 28 Coprogen_oxidas PF01218.13 CBZ50128.1 - 2e-113 377.8 1.0 1.4e-112 375.0 0.7 1.8 1 1 0 1 1 1 1 Coproporphyrinogen III oxidase TPR_11 PF13414.1 CBZ50129.1 - 1.4e-09 37.4 7.8 1e-06 28.2 1.1 2.5 1 1 1 2 2 2 2 TPR repeat TPR_12 PF13424.1 CBZ50129.1 - 0.00057 19.7 4.4 0.48 10.4 0.1 2.9 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 CBZ50129.1 - 0.0045 16.8 3.9 0.31 11.0 0.0 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 CBZ50129.1 - 0.035 13.8 0.7 1.4 8.9 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.23 CBZ50129.1 - 0.047 13.3 0.5 5 6.9 0.1 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_4 PF07721.9 CBZ50129.1 - 1.2 9.7 6.6 8.2 7.1 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.1 CBZ50129.1 - 1.5 9.5 6.5 6 7.6 0.1 3.0 2 1 1 3 3 3 0 Tetratricopeptide repeat Ribosomal_S10 PF00338.17 CBZ50131.1 - 5e-32 109.6 0.1 5.8e-32 109.4 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e MORN PF02493.15 CBZ50132.1 - 1.8e-29 99.7 42.0 5.6e-05 22.6 0.1 11.3 11 0 0 11 11 11 9 MORN repeat Cadherin-like PF12733.2 CBZ50132.1 - 1.6e-05 25.0 0.0 0.083 13.1 0.0 3.6 3 0 0 3 3 3 2 Cadherin-like beta sandwich domain Zeta_toxin PF06414.7 CBZ50135.1 - 0.00025 20.2 0.1 0.0053 15.8 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin AAA_19 PF13245.1 CBZ50135.1 - 0.00074 19.2 0.1 0.0022 17.7 0.0 1.8 2 0 0 2 2 2 1 Part of AAA domain AAA PF00004.24 CBZ50135.1 - 0.0013 18.9 0.0 0.0023 18.1 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 CBZ50135.1 - 0.0013 18.8 0.1 0.003 17.5 0.1 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.9 CBZ50135.1 - 0.0061 16.2 0.1 0.014 15.1 0.1 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_29 PF13555.1 CBZ50135.1 - 0.027 13.9 0.0 0.049 13.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_17 PF13207.1 CBZ50135.1 - 0.03 15.1 0.0 0.053 14.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 CBZ50135.1 - 0.037 13.8 2.3 0.11 12.3 0.1 2.5 3 0 0 3 3 3 0 AAA domain RuvB_N PF05496.7 CBZ50135.1 - 0.044 12.8 0.0 0.095 11.7 0.0 1.5 2 0 0 2 2 2 0 Holliday junction DNA helicase ruvB N-terminus AAA_18 PF13238.1 CBZ50135.1 - 0.049 13.9 0.0 0.11 12.7 0.0 1.7 2 0 0 2 2 2 0 AAA domain APS_kinase PF01583.15 CBZ50135.1 - 0.052 13.2 0.0 0.089 12.4 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase RNA_helicase PF00910.17 CBZ50135.1 - 0.053 13.6 0.0 0.11 12.6 0.0 1.6 1 0 0 1 1 1 0 RNA helicase ABC_tran PF00005.22 CBZ50135.1 - 0.085 13.1 0.0 0.38 11.0 0.0 2.0 2 0 0 2 2 2 0 ABC transporter GLTP PF08718.6 CBZ50136.1 - 2.4e-31 108.8 0.0 3.1e-31 108.4 0.0 1.1 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) Spore_YtfJ PF09579.5 CBZ50136.1 - 0.024 14.4 0.0 0.047 13.5 0.0 1.5 1 1 0 1 1 1 0 Sporulation protein YtfJ (Spore_YtfJ) CKS PF01111.14 CBZ50137.1 - 2.8e-07 30.2 2.8 4.8e-07 29.5 1.9 1.4 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit Ribonuclease_T2 PF00445.13 CBZ50137.1 - 0.058 13.0 0.1 0.061 12.9 0.0 1.1 1 0 0 1 1 1 0 Ribonuclease T2 family DUF1462 PF07315.6 CBZ50137.1 - 0.25 11.3 1.5 0.34 10.9 1.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1462) TRM13 PF05206.9 CBZ50138.1 - 1.4e-25 90.0 0.1 8.5e-25 87.4 0.1 2.1 1 1 0 1 1 1 1 Methyltransferase TRM13 ubiquitin PF00240.18 CBZ50138.1 - 4.4e-16 58.0 0.1 8.1e-16 57.1 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 CBZ50138.1 - 1.4e-07 31.0 0.1 3.5e-07 29.8 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Methyltransf_32 PF13679.1 CBZ50138.1 - 0.0096 15.6 5.1 6 6.5 0.0 3.5 3 0 0 3 3 3 2 Methyltransferase domain tRNA_bind PF01588.15 CBZ50139.1 - 5e-28 96.7 0.0 8e-28 96.1 0.0 1.3 1 0 0 1 1 1 1 Putative tRNA binding domain GST_C_2 PF13410.1 CBZ50139.1 - 7.2e-06 25.8 0.1 1.2e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 CBZ50139.1 - 1.3e-05 25.5 0.0 2.7e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 CBZ50139.1 - 2.1e-05 24.4 0.0 3.9e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain START PF01852.14 CBZ50140.1 - 2.2e-06 27.1 0.0 4.2e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 START domain His_Phos_1 PF00300.17 CBZ50141.1 - 2.2e-42 144.8 0.0 3e-42 144.4 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) PE-PPE PF08237.6 CBZ50141.1 - 0.13 11.6 0.0 0.22 10.9 0.0 1.4 1 0 0 1 1 1 0 PE-PPE domain Carb_anhydrase PF00194.16 CBZ50142.1 - 1.6e-12 46.9 1.4 3.7e-10 39.2 0.1 3.1 3 0 0 3 3 3 3 Eukaryotic-type carbonic anhydrase Phos_pyr_kin PF08543.7 CBZ50143.1 - 0.00031 20.0 0.0 0.0014 17.8 0.0 1.8 2 0 0 2 2 2 1 Phosphomethylpyrimidine kinase PfkB PF00294.19 CBZ50143.1 - 0.044 12.9 0.0 2.7 7.0 0.0 2.6 3 0 0 3 3 3 0 pfkB family carbohydrate kinase Kinesin PF00225.18 CBZ50146.1 - 2.2e-96 322.4 0.0 1e-94 317.0 0.0 3.1 2 1 0 2 2 2 1 Kinesin motor domain DUF16 PF01519.11 CBZ50146.1 - 4.9 7.4 15.8 2.3 8.4 1.8 3.4 3 0 0 3 3 3 0 Protein of unknown function DUF16 Acetyltransf_CG PF14542.1 CBZ50147.1 - 0.078 12.8 0.0 0.2 11.5 0.0 1.6 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Peptidase_M3_N PF08439.5 CBZ50147.1 - 0.19 11.8 0.8 0.69 9.9 0.5 1.9 1 0 0 1 1 1 0 Oligopeptidase F OmpH PF03938.9 CBZ50147.1 - 1.2 9.0 4.2 0.22 11.4 0.2 1.7 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) RNA_pol_I_A49 PF06870.7 CBZ50148.1 - 0.028 12.9 0.1 0.096 11.2 0.0 1.7 2 0 0 2 2 2 0 A49-like RNA polymerase I associated factor LSM PF01423.17 CBZ50149.1 - 6.6e-13 48.0 0.0 8.4e-13 47.6 0.0 1.1 1 0 0 1 1 1 1 LSM domain MORN PF02493.15 CBZ50150.1 - 6.5e-48 157.6 47.4 1.3e-06 27.7 0.5 9.6 9 0 0 9 9 9 9 MORN repeat DdrB PF12747.2 CBZ50150.1 - 0.0081 15.8 0.4 0.017 14.7 0.3 1.5 1 0 0 1 1 1 1 DdrB-like protein Coa1 PF08695.5 CBZ50151.1 - 0.00033 20.1 0.0 0.00069 19.0 0.0 1.5 1 0 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 FLO_LFY PF01698.11 CBZ50151.1 - 1.6 7.4 13.1 4.8 5.9 0.2 2.3 2 0 0 2 2 2 0 Floricaula / Leafy protein Ribosomal_L17 PF01196.14 CBZ50152.1 - 4.7e-18 65.5 0.0 6.7e-18 65.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L17 R3H PF01424.17 CBZ50152.1 - 0.89 9.2 4.1 0.21 11.2 0.2 2.0 3 0 0 3 3 3 0 R3H domain STAS_2 PF13466.1 CBZ50153.1 - 0.045 13.7 4.1 0.83 9.7 0.1 3.7 3 0 0 3 3 3 0 STAS domain CRAL_TRIO PF00650.15 CBZ50153.1 - 0.051 13.0 0.0 0.085 12.3 0.0 1.2 1 0 0 1 1 1 0 CRAL/TRIO domain BNR_2 PF13088.1 CBZ50153.1 - 0.11 11.8 0.0 0.18 11.0 0.0 1.3 1 0 0 1 1 1 0 BNR repeat-like domain DUF4146 PF13652.1 CBZ50153.1 - 0.13 12.0 0.0 7.4 6.4 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4146) AMP-binding PF00501.23 CBZ50155.1 - 4.9e-79 265.6 0.0 1.2e-78 264.3 0.0 1.6 1 1 0 1 1 1 1 AMP-binding enzyme Vps53_N PF04100.7 CBZ50156.1 - 4.1e-57 193.7 5.6 2.6e-33 115.3 1.5 4.1 3 1 0 3 3 3 3 Vps53-like, N-terminal ING PF12998.2 CBZ50156.1 - 0.057 13.6 0.3 13 6.1 0.0 2.7 2 0 0 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding Zw10 PF06248.8 CBZ50156.1 - 0.08 11.0 1.9 0.16 10.0 1.3 1.5 1 0 0 1 1 1 0 Centromere/kinetochore Zw10 DUF2884 PF11101.3 CBZ50156.1 - 0.1 11.9 3.7 0.12 11.7 1.2 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2884) COG2 PF06148.6 CBZ50156.1 - 0.11 12.3 2.4 0.34 10.7 1.7 1.8 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 MFS_1 PF07690.11 CBZ50157.1 - 5e-13 48.4 44.1 3.5e-12 45.7 25.6 3.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 CBZ50157.1 - 0.00059 18.3 16.3 0.00091 17.7 0.5 2.6 2 0 0 2 2 2 2 MFS/sugar transport protein Drc1-Sld2 PF11719.3 CBZ50160.1 - 0.1 11.6 4.3 0.12 11.3 2.9 1.0 1 0 0 1 1 1 0 DNA replication and checkpoint protein Lin-8 PF03353.10 CBZ50160.1 - 8 5.6 7.8 8 5.6 5.4 1.0 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist DUF2890 PF11081.3 CBZ50160.1 - 8.5 6.3 9.9 10 6.1 6.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) Pro_CA PF00484.14 CBZ50162.1 - 0.49 10.3 1.2 0.59 10.1 0.2 1.6 2 0 0 2 2 2 0 Carbonic anhydrase Daxx PF03344.10 CBZ50163.1 - 0.55 8.6 34.3 1.7 7.0 23.8 1.8 1 0 0 1 1 1 0 Daxx Family Spore_coat_CotO PF14153.1 CBZ50163.1 - 1.8 7.9 16.2 5.6 6.3 11.3 1.8 1 0 0 1 1 1 0 Spore coat protein CotO Syntaxin_2 PF14523.1 CBZ50165.1 - 0.014 15.4 1.1 0.014 15.4 0.7 2.8 2 1 1 3 3 3 0 Syntaxin-like protein FANCI_S1-cap PF14674.1 CBZ50166.1 - 2.5 8.2 10.3 9.6 6.3 0.9 4.0 3 0 0 3 3 3 0 FANCI solenoid 1 cap Reo_sigmaC PF04582.7 CBZ50166.1 - 7.2 5.6 11.2 1.5 7.8 3.2 2.5 1 1 2 3 3 3 0 Reovirus sigma C capsid protein TIP49 PF06068.8 CBZ50167.1 - 1.2e-135 452.2 4.8 6.6e-80 268.7 0.1 2.1 1 1 1 2 2 2 2 TIP49 C-terminus WD40 PF00400.27 CBZ50167.1 - 1e-12 47.4 5.1 0.073 12.9 0.0 7.0 7 0 0 7 7 7 3 WD domain, G-beta repeat AAA PF00004.24 CBZ50167.1 - 1.9e-10 41.0 0.8 1.2e-08 35.2 0.2 3.2 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 CBZ50167.1 - 7.7e-09 34.9 2.5 8.6e-06 24.9 0.0 3.0 2 1 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 CBZ50167.1 - 2.1e-07 31.1 0.0 1.3e-05 25.2 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 CBZ50167.1 - 8.1e-07 29.2 0.2 8.5e-06 25.9 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.9 CBZ50167.1 - 9.4e-05 22.1 0.1 0.0066 16.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 CBZ50167.1 - 0.00022 20.9 0.0 0.00073 19.2 0.0 1.9 1 0 0 1 1 1 1 Part of AAA domain AAA_18 PF13238.1 CBZ50167.1 - 0.00032 21.0 0.0 0.00073 19.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 CBZ50167.1 - 0.0016 17.8 0.0 0.0029 17.0 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.16 CBZ50167.1 - 0.0017 17.5 0.2 0.025 13.7 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_17 PF13207.1 CBZ50167.1 - 0.0021 18.8 0.0 0.0062 17.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 CBZ50167.1 - 0.0024 17.7 0.2 7.4 6.4 0.0 3.8 2 1 1 4 4 4 0 AAA domain AAA_25 PF13481.1 CBZ50167.1 - 0.0037 16.6 0.0 0.01 15.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.1 CBZ50167.1 - 0.0049 16.8 0.0 0.014 15.3 0.0 1.9 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.21 CBZ50167.1 - 0.0098 15.3 0.1 2.5 7.5 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain Zeta_toxin PF06414.7 CBZ50167.1 - 0.01 14.9 0.1 0.023 13.8 0.1 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_33 PF13671.1 CBZ50167.1 - 0.016 15.1 0.0 0.063 13.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain DnaB_C PF03796.10 CBZ50167.1 - 0.034 13.0 0.0 0.061 12.1 0.0 1.3 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain AAA_11 PF13086.1 CBZ50167.1 - 0.062 12.8 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.4 CBZ50167.1 - 0.087 11.7 0.0 0.14 11.1 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Parvo_NS1 PF01057.12 CBZ50167.1 - 0.13 11.1 0.0 0.22 10.3 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Protocadherin PF08374.6 CBZ50168.1 - 3.4 7.2 8.7 1.1e+02 2.2 0.0 2.4 2 0 0 2 2 2 0 Protocadherin TEX15 PF15326.1 CBZ50169.1 - 5.5 6.5 9.8 10 5.6 6.8 1.3 1 0 0 1 1 1 0 Testis expressed sequence 15 TFCD_C PF12612.3 CBZ50170.1 - 1.8e-05 24.2 5.3 0.00047 19.6 0.0 4.5 6 0 0 6 6 6 2 Tubulin folding cofactor D C terminal HEAT_EZ PF13513.1 CBZ50170.1 - 0.041 14.3 0.1 0.041 14.3 0.0 8.8 8 2 2 10 10 10 0 HEAT-like repeat Vac14_Fab1_bd PF12755.2 CBZ50170.1 - 0.047 14.0 0.0 0.52 10.7 0.0 2.8 3 0 0 3 3 3 0 Vacuolar 14 Fab1-binding region FoP_duplication PF13865.1 CBZ50171.1 - 2.7e-19 69.3 5.2 2.7e-19 69.3 3.6 4.6 1 1 3 4 4 4 1 C-terminal duplication domain of Friend of PRMT1 WD40 PF00400.27 CBZ50172.1 - 1.3e-05 24.9 1.1 1.2 9.1 0.0 5.6 6 0 0 6 6 6 3 WD domain, G-beta repeat EF-hand_6 PF13405.1 CBZ50173.1 - 0.04 13.8 0.1 0.15 12.0 0.0 2.0 1 0 0 1 1 1 0 EF-hand domain V_ATPase_I PF01496.14 CBZ50174.1 - 0.3 8.8 4.5 0.55 8.0 3.1 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Cpn60_TCP1 PF00118.19 CBZ50175.1 - 4e-143 477.5 0.2 4.5e-143 477.3 0.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family PPTA PF01239.17 CBZ50176.1 - 2.5e-21 74.0 7.1 2.7e-07 29.6 0.4 4.5 4 0 0 4 4 4 4 Protein prenyltransferase alpha subunit repeat IncA PF04156.9 CBZ50177.1 - 0.0044 16.6 15.4 0.0044 16.6 10.7 4.2 2 1 1 3 3 3 1 IncA protein Reo_sigmaC PF04582.7 CBZ50177.1 - 1.8 7.6 15.4 0.33 10.1 0.5 3.3 3 0 0 3 3 3 0 Reovirus sigma C capsid protein RNA_pol_Rpb2_6 PF00562.23 CBZ50178.1 - 2.9e-115 385.1 0.0 3.8e-115 384.7 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 CBZ50178.1 - 1.4e-23 82.8 0.0 2.5e-23 82.0 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_3 PF04565.11 CBZ50178.1 - 3.5e-22 77.9 0.0 6.9e-22 76.9 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_7 PF04560.15 CBZ50178.1 - 5.7e-14 52.1 0.0 1.8e-13 50.5 0.0 1.8 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpa2_4 PF06883.7 CBZ50178.1 - 0.1 12.5 0.0 0.33 10.9 0.0 1.9 1 0 0 1 1 1 0 RNA polymerase I, Rpa2 specific domain G-patch_2 PF12656.2 CBZ50178.1 - 0.14 12.0 0.1 0.31 10.9 0.1 1.5 1 0 0 1 1 1 0 DExH-box splicing factor binding site RNA_pol_Rpb2_5 PF04567.12 CBZ50178.1 - 0.16 11.9 0.0 0.33 10.9 0.0 1.5 1 0 0 1 1 1 0 RNA polymerase Rpb2, domain 5 Acyltransferase PF01553.16 CBZ50179.1 - 1.5e-21 76.1 0.0 2.2e-21 75.6 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase Metallophos PF00149.23 CBZ50181.1 - 7.4e-11 41.8 0.0 4.4e-10 39.3 0.0 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase DUF4200 PF13863.1 CBZ50183.1 - 5.8e-14 52.1 11.9 5.8e-14 52.1 8.2 3.8 2 2 2 4 4 4 1 Domain of unknown function (DUF4200) Fib_alpha PF08702.5 CBZ50183.1 - 0.011 15.9 5.3 0.011 15.9 3.7 2.9 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family SOG2 PF10428.4 CBZ50183.1 - 0.25 9.9 6.5 0.037 12.6 1.4 1.8 2 1 0 2 2 2 0 RAM signalling pathway protein Tet_JBP PF12851.2 CBZ50183.1 - 1.5 8.1 4.6 2.3 7.4 0.3 2.4 2 0 0 2 2 2 0 Oxygenase domain of the 2OGFeDO superfamily YPEB PF14620.1 CBZ50183.1 - 3.7 6.4 20.6 3.5 6.5 2.7 2.8 1 1 2 3 3 3 0 YpeB sporulation DUF4320 PF14208.1 CBZ50183.1 - 4.1 7.3 6.3 0.93 9.4 0.2 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4320) NPV_P10 PF05531.7 CBZ50183.1 - 4.6 7.5 6.9 15 5.8 0.5 3.6 4 0 0 4 4 4 0 Nucleopolyhedrovirus P10 protein EF-hand_7 PF13499.1 CBZ50184.1 - 3e-08 33.6 0.8 5.9e-08 32.7 0.4 1.6 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 CBZ50184.1 - 3.4e-07 29.5 0.9 9e-06 25.1 0.0 2.8 2 2 1 3 3 3 1 EF-hand domain EF-hand_1 PF00036.27 CBZ50184.1 - 1.6e-06 26.9 0.5 3.8e-05 22.6 0.0 2.9 3 1 0 3 3 3 1 EF hand EF-hand_5 PF13202.1 CBZ50184.1 - 0.00042 19.5 0.0 0.0018 17.5 0.0 2.1 2 0 0 2 2 2 1 EF hand tRNA-synt_1c_C PF03950.13 CBZ50184.1 - 0.0055 16.4 0.0 0.0063 16.1 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain EF-hand_8 PF13833.1 CBZ50184.1 - 0.0055 16.2 0.6 0.35 10.5 0.0 2.6 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_9 PF14658.1 CBZ50184.1 - 0.019 14.8 0.0 0.022 14.6 0.0 1.2 1 0 0 1 1 1 0 EF-hand domain Glyco_transf_20 PF00982.16 CBZ50187.1 - 4.3e-124 414.5 0.0 7e-124 413.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 CBZ50187.1 - 2.8e-56 190.0 0.0 3.3e-55 186.5 0.0 2.1 2 0 0 2 2 2 1 Trehalose-phosphatase CBM_20 PF00686.14 CBZ50187.1 - 2.5e-16 59.0 0.0 4.9e-16 58.1 0.0 1.5 1 0 0 1 1 1 1 Starch binding domain Hydrolase_3 PF08282.7 CBZ50187.1 - 0.00023 20.8 0.0 0.0024 17.4 0.0 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Elf1 PF05129.8 CBZ50188.1 - 1.2e-26 92.1 0.2 1.9e-26 91.5 0.1 1.3 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like SLX9 PF15341.1 CBZ50190.1 - 6.6e-17 62.0 0.0 6.6e-17 62.0 0.0 2.1 1 1 1 2 2 2 1 Ribosome biogenesis protein SLX9 DUF566 PF04484.7 CBZ50190.1 - 0.9 8.9 6.7 1.4 8.3 4.6 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF566) Cupin_8 PF13621.1 CBZ50192.1 - 1.3 8.4 10.7 1.6 8.2 7.4 1.2 1 0 0 1 1 1 0 Cupin-like domain BASP1 PF05466.7 CBZ50192.1 - 5.2 6.8 40.4 6.1 6.5 28.0 1.2 1 0 0 1 1 1 0 Brain acid soluble protein 1 (BASP1 protein) SAPS PF04499.10 CBZ50192.1 - 7.6 5.0 19.8 8.3 4.9 13.7 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DNA_gyraseB PF00204.20 CBZ50193.1 - 3.6e-26 91.4 0.1 1.2e-20 73.4 0.1 2.4 2 0 0 2 2 2 2 DNA gyrase B Toprim PF01751.17 CBZ50193.1 - 7.7e-26 89.9 0.1 1.2e-24 86.2 0.0 2.8 3 0 0 3 3 3 1 Toprim domain DNA_gyraseB_C PF00986.16 CBZ50193.1 - 4.5e-24 83.9 0.1 9e-24 83.0 0.0 1.5 1 0 0 1 1 1 1 DNA gyrase B subunit, carboxyl terminus HATPase_c PF02518.21 CBZ50193.1 - 9.8e-13 47.8 0.0 2e-12 46.8 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim_4 PF13662.1 CBZ50193.1 - 0.0047 16.8 0.1 0.046 13.7 0.0 2.7 2 1 0 2 2 2 1 Toprim domain HATPase_c_3 PF13589.1 CBZ50193.1 - 0.02 14.5 0.0 0.052 13.2 0.0 1.6 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Prothymosin PF03247.9 CBZ50193.1 - 7.9 6.6 32.7 3.6 7.7 5.6 2.6 2 0 0 2 2 2 0 Prothymosin/parathymosin family SMC_N PF02463.14 CBZ50196.1 - 5.3e-28 97.7 13.8 1.2e-27 96.6 9.6 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 CBZ50196.1 - 1.2e-19 70.4 0.1 5e-19 68.4 0.0 2.2 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.1 CBZ50196.1 - 9e-06 26.1 59.3 31 4.8 35.6 5.0 2 1 0 2 2 2 0 AAA domain AAA_21 PF13304.1 CBZ50196.1 - 9.7e-05 22.4 0.0 0.00027 20.9 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 CBZ50196.1 - 0.003 17.0 0.0 0.0069 15.8 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain GAS PF13851.1 CBZ50196.1 - 0.0051 16.0 18.1 0.0051 16.0 12.5 4.7 4 1 0 4 4 4 2 Growth-arrest specific micro-tubule binding Metal_resist PF13801.1 CBZ50196.1 - 0.0085 16.0 14.5 0.0085 16.0 10.1 4.3 2 1 2 5 5 4 1 Heavy-metal resistance AAA_15 PF13175.1 CBZ50196.1 - 0.012 14.6 0.0 0.012 14.6 0.0 2.5 2 1 0 2 2 1 0 AAA ATPase domain DUF717 PF05338.7 CBZ50196.1 - 0.053 13.4 0.2 0.29 11.0 0.2 2.3 1 0 0 1 1 1 0 Protein of unknown function (DUF717) APG6 PF04111.7 CBZ50196.1 - 0.083 11.9 70.0 0.02 13.9 3.3 4.5 2 1 0 3 3 3 0 Autophagy protein Apg6 ABC_tran PF00005.22 CBZ50196.1 - 4.1 7.7 0.0 4.1 7.7 0.0 4.2 3 1 1 4 4 4 0 ABC transporter Arm PF00514.18 CBZ50198.1 - 8.2e-34 114.2 16.3 4.1e-08 32.7 0.0 8.5 9 0 0 9 9 9 6 Armadillo/beta-catenin-like repeat HEAT PF02985.17 CBZ50198.1 - 2.7e-15 55.0 3.4 1.1e-06 28.1 0.0 5.9 5 0 0 5 5 5 3 HEAT repeat HEAT_2 PF13646.1 CBZ50198.1 - 6.6e-15 55.1 12.2 5.5e-07 29.7 0.1 4.4 2 2 1 3 3 3 3 HEAT repeats HEAT_EZ PF13513.1 CBZ50198.1 - 1.7e-11 44.2 12.3 0.0054 17.1 0.0 5.3 3 1 3 6 6 6 4 HEAT-like repeat Adaptin_N PF01602.15 CBZ50198.1 - 3.9e-08 32.0 0.2 1.8e-05 23.2 0.1 3.2 2 2 1 3 3 3 1 Adaptin N terminal region Proteasom_PSMB PF10508.4 CBZ50198.1 - 4.4e-07 28.5 1.0 3.1e-05 22.4 0.1 2.7 1 1 0 1 1 1 1 Proteasome non-ATPase 26S subunit Cnd1 PF12717.2 CBZ50198.1 - 3.3e-05 23.8 0.0 0.00049 19.9 0.0 2.4 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 Atx10homo_assoc PF09759.4 CBZ50198.1 - 0.00065 19.3 0.1 2.4 7.9 0.1 3.1 3 0 0 3 3 3 2 Spinocerebellar ataxia type 10 protein domain V-ATPase_H_C PF11698.3 CBZ50198.1 - 0.0054 16.6 0.4 0.1 12.5 0.0 3.0 3 1 0 3 3 3 1 V-ATPase subunit H CLASP_N PF12348.3 CBZ50198.1 - 0.0062 15.9 0.3 0.26 10.5 0.0 2.5 2 0 0 2 2 2 1 CLASP N terminal HEAT_PBS PF03130.11 CBZ50198.1 - 0.024 15.0 8.5 4.5 8.0 0.0 6.1 6 0 0 6 6 6 0 PBS lyase HEAT-like repeat EcoEI_R_C PF08463.5 CBZ50198.1 - 0.051 13.4 0.0 0.14 11.9 0.0 1.9 1 1 0 1 1 1 0 EcoEI R protein C-terminal Vac14_Fab1_bd PF12755.2 CBZ50198.1 - 0.058 13.7 0.0 0.35 11.2 0.0 2.4 2 1 1 3 3 3 0 Vacuolar 14 Fab1-binding region Cnd3 PF12719.2 CBZ50198.1 - 0.11 11.4 3.3 4.2 6.2 1.1 2.8 2 1 0 2 2 2 0 Nuclear condensing complex subunits, C-term domain MRP-S31 PF15433.1 CBZ50199.1 - 0.42 9.9 11.6 0.71 9.2 8.0 1.2 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 DUF3138 PF11336.3 CBZ50199.1 - 5.5 5.0 9.3 9.9 4.2 6.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) DNA_primase_lrg PF04104.9 CBZ50200.1 - 2.2e-59 200.8 0.0 2.7e-59 200.5 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit Aminotran_4 PF01063.14 CBZ50201.1 - 1.8e-14 53.7 0.0 2.6e-14 53.2 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class IV FRD2 PF03197.8 CBZ50203.1 - 0.039 14.4 0.0 0.064 13.8 0.0 1.3 1 0 0 1 1 1 0 Bacteriophage FRD2 protein NT5C PF06941.7 CBZ50203.1 - 0.059 12.8 0.3 0.11 11.9 0.1 1.5 1 1 1 2 2 2 0 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) DUF2815 PF10991.3 CBZ50207.1 - 0.013 15.0 4.1 0.019 14.4 2.2 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2815) Fe-S_biosyn PF01521.15 CBZ50208.1 - 4e-17 62.1 0.0 5.7e-17 61.6 0.0 1.1 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis SSB PF00436.20 CBZ50209.1 - 6.4e-08 32.4 0.1 6.1e-06 26.0 0.1 2.4 2 0 0 2 2 2 2 Single-strand binding protein family Peptidase_M18 PF02127.10 CBZ50211.1 - 4.3e-143 476.9 0.0 6.6e-143 476.2 0.0 1.3 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.9 CBZ50211.1 - 0.0001 21.1 0.0 0.0014 17.4 0.0 2.1 2 0 0 2 2 2 1 M42 glutamyl aminopeptidase eIF3_p135 PF12807.2 CBZ50213.1 - 7.1e-12 45.5 0.7 1e-10 41.7 0.0 2.6 2 0 0 2 2 2 1 Translation initiation factor eIF3 subunit 135 TPR_12 PF13424.1 CBZ50213.1 - 0.0025 17.7 3.8 0.028 14.3 0.4 3.6 2 1 1 3 3 3 1 Tetratricopeptide repeat STAT6_C PF14596.1 CBZ50213.1 - 0.061 13.2 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 STAT6 C-terminal TMEM247 PF15444.1 CBZ50213.1 - 0.21 11.3 3.3 0.53 10.0 1.1 2.3 2 0 0 2 2 2 0 Transmembrane protein 247 DEAD PF00270.24 CBZ50214.1 - 2e-39 134.7 1.2 2.5e-39 134.4 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Ubiq_cyt_C_chap PF03981.7 CBZ50215.1 - 7.1e-19 68.0 0.3 2.3e-12 46.9 0.0 2.5 2 0 0 2 2 2 2 Ubiquinol-cytochrome C chaperone Helicase_C PF00271.26 CBZ50215.1 - 1.1e-13 50.8 0.1 5e-13 48.7 0.0 2.1 3 0 0 3 3 3 1 Helicase conserved C-terminal domain RBFA PF02033.13 CBZ50216.1 - 9.4e-09 35.2 0.0 1.5e-08 34.5 0.0 1.3 1 0 0 1 1 1 1 Ribosome-binding factor A Nse4_C PF08743.5 CBZ50217.1 - 0.00057 19.8 0.0 0.0014 18.6 0.0 1.6 1 0 0 1 1 1 1 Nse4 C-terminal CobA_CobO_BtuR PF02572.10 CBZ50218.1 - 0.032 13.8 0.2 0.038 13.6 0.1 1.3 1 1 0 1 1 1 0 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP Peptidase_A17 PF05380.8 CBZ50218.1 - 0.053 13.3 0.1 0.063 13.1 0.0 1.1 1 0 0 1 1 1 0 Pao retrotransposon peptidase Ca_hom_mod PF14798.1 CBZ50218.1 - 0.074 11.9 0.0 0.084 11.8 0.0 1.0 1 0 0 1 1 1 0 Calcium homeostasis modulator His_Phos_1 PF00300.17 CBZ50219.1 - 4.9e-15 55.9 0.4 6.1e-10 39.4 0.0 2.3 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) Syntaxin-6_N PF09177.6 CBZ50219.1 - 0.014 15.7 1.0 0.029 14.7 0.2 1.9 2 0 0 2 2 2 0 Syntaxin 6, N-terminal CDP-OH_P_transf PF01066.16 CBZ50221.1 - 9.4e-13 48.3 0.3 9.4e-13 48.3 0.2 3.1 3 1 0 3 3 3 1 CDP-alcohol phosphatidyltransferase DUF3591 PF12157.3 CBZ50222.1 - 2.3e-21 75.7 0.5 6.7e-08 31.3 0.0 4.6 3 2 0 3 3 3 3 Protein of unknown function (DUF3591) Bromodomain PF00439.20 CBZ50222.1 - 4.9e-17 61.6 0.0 9.3e-17 60.7 0.0 1.4 1 0 0 1 1 1 1 Bromodomain zf-CCHC_6 PF15288.1 CBZ50222.1 - 0.00053 19.5 1.6 0.0016 18.0 1.1 1.8 1 0 0 1 1 1 1 Zinc knuckle DUF966 PF06136.8 CBZ50222.1 - 0.0026 17.2 4.0 0.0073 15.7 2.8 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF966) zf-CCHC PF00098.18 CBZ50222.1 - 0.0085 15.9 0.2 0.024 14.5 0.2 1.8 1 0 0 1 1 1 1 Zinc knuckle Drf_GBD PF06371.8 CBZ50222.1 - 0.43 9.8 0.5 0.9 8.8 0.4 1.4 1 0 0 1 1 1 0 Diaphanous GTPase-binding Domain PI3_PI4_kinase PF00454.22 CBZ50223.1 - 2.4e-24 86.1 0.0 5e-24 85.0 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase AMP-binding PF00501.23 CBZ50224.1 - 9.7e-18 63.7 0.1 1.1e-13 50.4 0.0 2.2 1 1 0 2 2 2 2 AMP-binding enzyme Arf PF00025.16 CBZ50225.1 - 2.8e-78 261.1 0.1 3.2e-78 260.9 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 CBZ50225.1 - 2.7e-14 52.8 0.0 3.3e-14 52.5 0.0 1.0 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 CBZ50225.1 - 3.4e-13 49.2 0.0 3.7e-13 49.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.7 CBZ50225.1 - 3.8e-12 45.8 0.0 4.5e-12 45.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.15 CBZ50225.1 - 2.5e-11 42.8 0.8 5.3e-08 31.9 0.1 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Miro PF08477.8 CBZ50225.1 - 1.2e-08 35.4 0.0 1.7e-08 35.0 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 CBZ50225.1 - 2.4e-05 24.2 0.0 3.2e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.13 CBZ50225.1 - 0.006 15.6 0.2 0.011 14.8 0.0 1.5 2 0 0 2 2 2 1 6-phosphofructo-2-kinase GTP_EFTU PF00009.22 CBZ50225.1 - 0.0099 15.3 0.1 0.08 12.3 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_33 PF13671.1 CBZ50225.1 - 0.052 13.4 0.1 0.09 12.6 0.1 1.7 1 1 0 1 1 1 0 AAA domain Peptidase_C1 PF00112.18 CBZ50226.1 - 1.6e-33 116.4 2.9 2.4e-33 115.8 2.0 1.2 1 0 0 1 1 1 1 Papain family cysteine protease CathepsinC_exc PF08773.6 CBZ50226.1 - 1e-09 38.5 0.1 5.4e-08 33.0 0.0 2.5 2 0 0 2 2 2 1 Cathepsin C exclusion domain Peptidase_C1_2 PF03051.10 CBZ50226.1 - 0.13 10.7 2.7 0.2 10.1 1.9 1.1 1 0 0 1 1 1 0 Peptidase C1-like family SET PF00856.23 CBZ50227.1 - 8.7e-09 35.8 0.3 5.6e-08 33.2 0.1 2.2 2 0 0 2 2 2 1 SET domain Cyt-b5 PF00173.23 CBZ50228.1 - 6.2e-25 86.8 0.0 8e-25 86.4 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain YqzH PF14164.1 CBZ50228.1 - 0.11 12.4 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 YqzH-like protein Coq4 PF05019.8 CBZ50231.1 - 8.9e-56 188.2 0.1 1.9e-50 170.8 0.1 2.1 2 0 0 2 2 2 2 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 Tubulin PF00091.20 CBZ50232.1 - 5.1e-58 196.4 0.0 6.4e-58 196.1 0.0 1.0 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Misat_Tub_SegII PF10644.4 CBZ50232.1 - 0.002 18.1 0.0 0.0049 16.8 0.0 1.7 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain DUF3382 PF11862.3 CBZ50233.1 - 0.12 12.3 0.1 3 7.7 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF3382) PP2C PF00481.16 CBZ50234.1 - 4.8e-05 22.8 0.0 0.01 15.2 0.0 2.8 2 1 0 3 3 3 2 Protein phosphatase 2C DNA_pol_A_exo1 PF01612.15 CBZ50235.1 - 4e-13 49.2 0.0 8.9e-10 38.3 0.0 2.2 2 0 0 2 2 2 2 3'-5' exonuclease CcdA PF07362.7 CBZ50235.1 - 0.32 10.8 4.2 0.9 9.4 2.9 1.7 1 0 0 1 1 1 0 Post-segregation antitoxin CcdA IncA PF04156.9 CBZ50236.1 - 0.42 10.1 2.4 1 8.9 1.7 1.4 1 1 0 1 1 1 0 IncA protein S10_plectin PF03501.10 CBZ50237.1 - 2.5e-40 136.2 0.2 3e-40 135.9 0.1 1.1 1 0 0 1 1 1 1 Plectin/S10 domain DUF2250 PF10007.4 CBZ50237.1 - 0.13 12.1 0.3 0.31 10.9 0.1 1.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2250) TPR_12 PF13424.1 CBZ50238.1 - 3.4e-12 46.1 40.0 6e-05 22.9 3.2 7.2 6 2 2 8 8 8 7 Tetratricopeptide repeat SRP72 PF08492.7 CBZ50238.1 - 8e-11 42.1 5.8 2e-10 40.8 4.1 1.7 1 0 0 1 1 1 1 SRP72 RNA-binding domain TPR_2 PF07719.12 CBZ50238.1 - 2e-10 39.7 28.9 0.12 12.3 0.5 9.6 10 0 0 10 10 10 4 Tetratricopeptide repeat Apc3 PF12895.2 CBZ50238.1 - 6.2e-09 35.8 16.8 1.3e-06 28.4 0.7 5.3 5 1 1 6 6 6 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.1 CBZ50238.1 - 6.1e-08 32.6 52.3 0.0045 17.4 0.3 10.3 7 2 3 10 10 10 3 Tetratricopeptide repeat TPR_19 PF14559.1 CBZ50238.1 - 6e-07 29.7 46.5 0.012 15.8 1.6 9.0 4 3 5 9 9 9 6 Tetratricopeptide repeat TPR_16 PF13432.1 CBZ50238.1 - 1.2e-06 29.0 50.4 0.0019 18.8 5.1 8.8 7 2 2 9 9 9 3 Tetratricopeptide repeat TPR_11 PF13414.1 CBZ50238.1 - 2.5e-06 27.0 24.8 0.1 12.2 0.1 6.9 6 2 2 8 8 8 5 TPR repeat TPR_4 PF07721.9 CBZ50238.1 - 0.00026 21.1 58.7 0.19 12.2 0.5 11.3 11 1 1 12 12 12 4 Tetratricopeptide repeat Coatomer_E PF04733.9 CBZ50238.1 - 0.00041 19.6 5.4 0.055 12.6 0.1 4.1 4 1 0 4 4 4 1 Coatomer epsilon subunit NARP1 PF12569.3 CBZ50238.1 - 0.0005 18.9 8.4 0.092 11.4 0.0 4.8 6 0 0 6 6 6 2 NMDA receptor-regulated protein 1 LppC PF04348.8 CBZ50238.1 - 0.0048 15.5 3.8 0.0048 15.5 2.6 1.9 1 1 1 2 2 2 1 LppC putative lipoprotein TPR_6 PF13174.1 CBZ50238.1 - 0.077 13.4 27.3 2.5 8.7 0.2 9.0 10 0 0 10 10 9 0 Tetratricopeptide repeat cEGF PF12662.2 CBZ50239.1 - 0.023 14.3 30.3 0.036 13.7 0.4 5.5 5 0 0 5 5 5 0 Complement Clr-like EGF-like cEGF PF12662.2 CBZ50240.1 - 2.9e-07 29.9 23.2 0.0013 18.3 0.1 4.6 4 0 0 4 4 4 3 Complement Clr-like EGF-like EGF PF00008.22 CBZ50240.1 - 1e-05 25.3 44.2 0.0021 17.9 4.6 5.3 4 0 0 4 4 4 4 EGF-like domain EGF_3 PF12947.2 CBZ50240.1 - 0.0041 17.0 50.5 0.062 13.2 0.3 6.1 5 1 0 5 5 5 4 EGF domain hEGF PF12661.2 CBZ50240.1 - 0.14 12.3 19.9 1.5 9.0 0.9 5.2 4 0 0 4 4 4 0 Human growth factor-like EGF Apt1 PF10351.4 CBZ50240.1 - 0.82 8.4 8.2 1.3 7.7 5.7 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain FXa_inhibition PF14670.1 CBZ50240.1 - 6.6 6.9 55.5 0.032 14.3 2.5 5.9 5 1 1 6 6 6 0 Coagulation Factor Xa inhibitory site Bap31 PF05529.7 CBZ50242.1 - 1.1e-05 24.9 0.0 2.1e-05 24.0 0.0 1.4 1 1 0 1 1 1 1 B-cell receptor-associated protein 31-like PGA2 PF07543.7 CBZ50243.1 - 0.00087 19.1 3.8 0.0074 16.0 2.7 2.1 1 1 0 1 1 1 1 Protein trafficking PGA2 EH_Signature PF15611.1 CBZ50243.1 - 0.0025 16.9 0.1 0.0028 16.7 0.0 1.1 1 0 0 1 1 1 1 EH_Signature domain Spore_SspJ PF09575.5 CBZ50243.1 - 0.13 12.5 0.5 0.13 12.5 0.3 1.9 2 0 0 2 2 2 0 Small spore protein J (Spore_SspJ) APC_CDC26 PF10471.4 CBZ50243.1 - 0.72 10.6 7.2 6 7.6 1.3 2.7 3 1 0 3 3 3 0 Anaphase-promoting complex APC subunit 1 LSM PF01423.17 CBZ50244.1 - 1.7e-16 59.5 0.1 2.5e-16 58.9 0.0 1.2 1 0 0 1 1 1 1 LSM domain IMCp PF12314.3 CBZ50250.1 - 1.7e-25 88.9 29.4 1.7e-25 88.9 20.4 4.9 1 1 1 3 3 3 2 Inner membrane complex protein LCM PF04072.9 CBZ50251.1 - 2.1e-26 92.6 0.1 6.6e-26 90.9 0.0 1.8 2 0 0 2 2 2 1 Leucine carboxyl methyltransferase DUF4456 PF14644.1 CBZ50252.1 - 0.024 13.8 6.0 1.5 7.9 0.0 5.2 6 0 0 6 6 6 0 Domain of unknown function (DUF4456) BCA_ABC_TP_C PF12399.3 CBZ50252.1 - 0.069 12.8 0.8 55 3.5 0.0 5.2 5 0 0 5 5 5 0 Branched-chain amino acid ATP-binding cassette transporter HECT PF00632.20 CBZ50254.1 - 7.2e-98 327.6 0.0 9.5e-98 327.2 0.0 1.1 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) IQ PF00612.22 CBZ50254.1 - 0.086 12.5 0.7 0.36 10.6 0.5 2.2 1 0 0 1 1 1 0 IQ calmodulin-binding motif Pkinase PF00069.20 CBZ50255.1 - 3.2e-45 154.3 0.0 4.2e-45 153.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ50255.1 - 1.4e-18 66.9 0.0 2.1e-18 66.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 CBZ50255.1 - 0.00099 18.2 0.0 0.0022 17.0 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CBZ50255.1 - 0.0016 18.2 2.2 0.037 13.7 0.0 2.6 2 0 0 2 2 2 1 Phosphotransferase enzyme family DUF2431 PF10354.4 CBZ50255.1 - 0.2 11.5 0.0 0.39 10.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF2431) DAGAT PF03982.8 CBZ50256.1 - 3.6e-38 130.9 0.1 2.6e-26 92.0 0.0 3.0 2 1 1 3 3 3 2 Diacylglycerol acyltransferase Acyltransferase PF01553.16 CBZ50256.1 - 0.0031 16.9 0.0 0.013 14.9 0.0 1.9 2 0 0 2 2 2 1 Acyltransferase DUF4605 PF15378.1 CBZ50256.1 - 0.71 9.6 3.0 13 5.5 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4605) zf-DHHC PF01529.15 CBZ50257.1 - 2.8e-05 23.6 2.4 6e-05 22.5 1.6 1.5 1 1 0 1 1 1 1 DHHC palmitoyltransferase PPR_2 PF13041.1 CBZ50258.1 - 1.3e-59 197.9 14.6 2.5e-13 49.7 0.0 8.0 1 1 7 8 8 8 8 PPR repeat family PPR PF01535.15 CBZ50258.1 - 5e-45 148.3 13.5 2.3e-06 27.2 0.0 8.9 9 0 0 9 9 9 7 PPR repeat PPR_1 PF12854.2 CBZ50258.1 - 1.1e-39 133.5 0.1 4.5e-09 35.6 0.0 6.8 6 0 0 6 6 6 6 PPR repeat PPR_3 PF13812.1 CBZ50258.1 - 5.6e-34 113.5 4.7 0.00015 21.7 0.0 9.5 9 0 0 9 9 9 6 Pentatricopeptide repeat domain ATP13 PF12921.2 CBZ50258.1 - 0.027 13.8 0.0 29 4.0 0.0 3.4 3 1 0 3 3 3 0 Mitochondrial ATPase expression MRP-S27 PF10037.4 CBZ50258.1 - 0.9 8.3 0.0 3.1 6.6 0.0 1.6 1 1 2 3 3 3 0 Mitochondrial 28S ribosomal protein S27 TPR_11 PF13414.1 CBZ50259.1 - 3.1e-72 238.1 32.5 2.1e-19 68.8 0.3 6.3 6 0 0 6 6 6 6 TPR repeat TPR_1 PF00515.23 CBZ50259.1 - 2e-56 185.3 35.9 6.7e-08 31.8 2.5 9.4 9 0 0 9 9 9 9 Tetratricopeptide repeat TPR_2 PF07719.12 CBZ50259.1 - 5.1e-47 154.0 33.0 2.8e-06 26.8 2.0 9.5 9 0 0 9 9 9 9 Tetratricopeptide repeat TPR_12 PF13424.1 CBZ50259.1 - 9.1e-27 92.8 19.7 1.3e-10 41.0 0.5 6.6 3 3 3 6 6 6 5 Tetratricopeptide repeat TPR_16 PF13432.1 CBZ50259.1 - 3.5e-25 88.0 22.8 1.6e-08 34.9 0.8 7.4 5 2 3 8 8 8 4 Tetratricopeptide repeat TPR_14 PF13428.1 CBZ50259.1 - 5.2e-22 76.3 11.7 0.079 13.6 0.1 9.2 6 3 2 9 9 9 7 Tetratricopeptide repeat TPR_8 PF13181.1 CBZ50259.1 - 1.2e-16 59.1 33.3 0.011 15.4 0.0 8.7 9 0 0 9 9 8 6 Tetratricopeptide repeat TPR_17 PF13431.1 CBZ50259.1 - 3.1e-16 58.1 20.3 0.0023 18.0 0.4 10.1 12 0 0 12 12 11 3 Tetratricopeptide repeat TPR_9 PF13371.1 CBZ50259.1 - 5.6e-16 58.1 3.4 0.0051 16.6 0.0 6.1 4 2 1 5 5 5 4 Tetratricopeptide repeat TPR_19 PF14559.1 CBZ50259.1 - 1.4e-15 57.3 28.9 1.3e-05 25.4 1.3 7.2 5 2 1 7 7 7 3 Tetratricopeptide repeat TPR_7 PF13176.1 CBZ50259.1 - 6.3e-12 44.3 17.1 0.024 14.3 0.1 8.6 8 1 1 9 9 9 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 CBZ50259.1 - 9.8e-08 31.7 17.5 0.14 12.0 0.1 8.0 7 2 2 9 9 9 2 Fis1 C-terminal tetratricopeptide repeat ChAPs PF09295.5 CBZ50259.1 - 0.00021 20.1 5.0 0.57 8.8 0.2 3.5 3 1 0 3 3 3 3 ChAPs (Chs5p-Arf1p-binding proteins) TPR_10 PF13374.1 CBZ50259.1 - 0.00045 20.0 19.6 0.34 10.9 0.0 8.0 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_6 PF13174.1 CBZ50259.1 - 0.0039 17.5 31.4 0.57 10.7 0.3 8.9 8 1 1 9 9 9 2 Tetratricopeptide repeat tRNA-synt_His PF13393.1 CBZ50259.1 - 1.2 8.0 14.0 1.6 7.7 2.9 3.4 2 1 2 4 4 4 0 Histidyl-tRNA synthetase RPN7 PF10602.4 CBZ50259.1 - 1.5 8.1 19.8 0.17 11.2 0.9 5.1 3 2 2 5 5 5 0 26S proteasome subunit RPN7 TPR_3 PF07720.7 CBZ50259.1 - 9.6 6.1 21.8 1.2 9.0 0.6 5.4 6 1 0 6 6 6 0 Tetratricopeptide repeat AAA PF00004.24 CBZ50261.1 - 1e-17 64.5 0.0 3.5e-14 53.1 0.0 4.0 4 0 0 4 4 4 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 CBZ50261.1 - 3.6e-08 33.0 3.1 7e-05 22.5 1.1 2.9 2 0 0 2 2 2 2 Part of AAA domain AAA_16 PF13191.1 CBZ50261.1 - 7.6e-06 26.0 4.6 0.0009 19.2 0.1 4.5 4 1 1 5 5 5 1 AAA ATPase domain AAA_22 PF13401.1 CBZ50261.1 - 2.6e-05 24.3 0.0 0.4 10.8 0.0 4.3 3 2 0 3 3 3 1 AAA domain RuvB_N PF05496.7 CBZ50261.1 - 0.0004 19.4 0.1 0.002 17.2 0.1 2.0 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus DUF2075 PF09848.4 CBZ50261.1 - 0.00042 19.3 0.0 0.0094 14.9 0.0 2.1 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_17 PF13207.1 CBZ50261.1 - 0.00047 20.9 0.0 0.31 11.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 CBZ50261.1 - 0.00049 19.2 0.3 0.0019 17.3 0.0 1.9 2 0 0 2 2 2 1 Zeta toxin AAA_18 PF13238.1 CBZ50261.1 - 0.00055 20.2 0.0 0.34 11.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 CBZ50261.1 - 0.00081 19.1 0.2 0.049 13.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 CBZ50261.1 - 0.0011 18.4 0.0 0.074 12.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 CBZ50261.1 - 0.0019 18.0 0.0 2.3 8.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain Sigma54_activ_2 PF14532.1 CBZ50261.1 - 0.0044 17.0 0.0 0.018 15.0 0.0 1.9 2 0 0 2 2 2 1 Sigma-54 interaction domain IstB_IS21 PF01695.12 CBZ50261.1 - 0.0051 16.2 0.1 0.019 14.3 0.0 1.9 2 0 0 2 2 2 1 IstB-like ATP binding protein TIP49 PF06068.8 CBZ50261.1 - 0.008 14.9 0.1 0.015 14.0 0.1 1.3 1 0 0 1 1 1 1 TIP49 C-terminus NACHT PF05729.7 CBZ50261.1 - 0.011 15.3 0.1 0.21 11.2 0.0 2.5 2 0 0 2 2 2 0 NACHT domain Sigma54_activat PF00158.21 CBZ50261.1 - 0.013 14.9 0.8 0.043 13.2 0.0 2.2 3 0 0 3 3 3 0 Sigma-54 interaction domain UPF0079 PF02367.12 CBZ50261.1 - 0.06 12.9 0.0 3.7 7.2 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 Viral_helicase1 PF01443.13 CBZ50261.1 - 0.15 11.5 0.0 8.4 5.8 0.0 2.2 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase ADK PF00406.17 CBZ50261.1 - 0.19 11.6 0.0 1.8 8.4 0.0 2.3 2 0 0 2 2 2 0 Adenylate kinase ResIII PF04851.10 CBZ50261.1 - 0.2 11.4 0.0 0.32 10.8 0.0 1.2 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit RNA_helicase PF00910.17 CBZ50261.1 - 0.2 11.8 0.0 0.67 10.1 0.0 1.8 2 0 0 2 2 2 0 RNA helicase KaiC PF06745.8 CBZ50261.1 - 0.28 10.2 0.0 0.75 8.8 0.0 1.6 2 0 0 2 2 2 0 KaiC Ribosomal_L1 PF00687.16 CBZ50263.1 - 1.3e-23 83.5 0.0 1.8e-23 83.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family SAE2 PF08573.5 CBZ50264.1 - 4.9e-08 33.5 8.5 4.5e-05 24.0 0.3 4.0 3 0 0 3 3 3 2 DNA repair protein endonuclease SAE2/CtIP C-terminus Arm PF00514.18 CBZ50265.1 - 9.5e-95 307.5 16.6 1e-13 50.5 0.0 8.8 9 0 0 9 9 9 8 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 CBZ50265.1 - 4.3e-29 100.6 2.0 3e-08 33.8 0.0 6.2 1 1 3 5 5 5 5 HEAT repeats HEAT_EZ PF13513.1 CBZ50265.1 - 9.3e-26 89.6 7.0 3.4e-10 40.1 0.0 6.1 6 1 1 7 7 6 5 HEAT-like repeat HEAT PF02985.17 CBZ50265.1 - 8.6e-18 62.7 9.5 6.8e-06 25.7 0.0 8.9 9 1 0 9 9 9 2 HEAT repeat Arm_2 PF04826.8 CBZ50265.1 - 1.7e-09 37.1 0.0 0.0031 16.6 0.0 4.0 1 1 3 4 4 4 3 Armadillo-like IBB PF01749.15 CBZ50265.1 - 2.6e-08 33.9 7.1 2.6e-08 33.9 2.8 2.2 2 0 0 2 2 2 1 Importin beta binding domain V-ATPase_H_C PF11698.3 CBZ50265.1 - 1.4e-06 28.2 0.0 0.4 10.6 0.0 4.4 4 0 0 4 4 4 1 V-ATPase subunit H Adaptin_N PF01602.15 CBZ50265.1 - 2.8e-05 22.6 0.0 0.00016 20.1 0.0 2.4 1 1 0 1 1 1 1 Adaptin N terminal region HEAT_PBS PF03130.11 CBZ50265.1 - 0.00059 20.0 7.7 0.26 11.8 0.1 5.9 6 0 0 6 6 4 1 PBS lyase HEAT-like repeat Proteasom_PSMB PF10508.4 CBZ50265.1 - 0.0021 16.4 0.1 0.45 8.7 0.0 2.9 2 1 1 3 3 3 1 Proteasome non-ATPase 26S subunit CLASP_N PF12348.3 CBZ50265.1 - 0.0045 16.3 0.1 4.5 6.5 0.0 3.8 2 1 2 4 4 4 1 CLASP N terminal Ric8 PF10165.4 CBZ50265.1 - 0.005 15.7 0.0 4.3 6.0 0.0 3.2 3 0 0 3 3 3 1 Guanine nucleotide exchange factor synembryn RICTOR_V PF14668.1 CBZ50265.1 - 0.0094 15.8 4.4 0.93 9.4 0.0 4.3 3 2 2 5 5 5 1 Rapamycin-insensitive companion of mTOR, domain 5 DUF4177 PF13783.1 CBZ50266.1 - 0.034 13.7 0.0 0.088 12.4 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4177) Sas10_Utp3 PF04000.10 CBZ50268.1 - 4.8e-12 45.9 0.0 7e-12 45.3 0.0 1.3 1 0 0 1 1 1 1 Sas10/Utp3/C1D family MBOAT PF03062.14 CBZ50269.1 - 0.016 14.3 29.7 0.034 13.2 6.7 3.9 4 0 0 4 4 4 0 MBOAT, membrane-bound O-acyltransferase family CytoC_RC PF02276.13 CBZ50270.1 - 0.09 11.8 0.0 0.12 11.5 0.0 1.1 1 0 0 1 1 1 0 Photosynthetic reaction centre cytochrome C subunit DUF4415 PF14384.1 CBZ50270.1 - 0.11 12.6 0.2 0.35 11.0 0.1 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4415) Kinase-like PF14531.1 CBZ50271.1 - 8.6e-41 139.7 0.0 1.3e-40 139.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase PF00069.20 CBZ50271.1 - 2.7e-16 59.4 0.0 4.3e-16 58.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ50271.1 - 0.0013 17.8 0.0 0.0024 17.0 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase DUF2802 PF10975.3 CBZ50271.1 - 0.13 11.9 0.0 0.33 10.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2802) PhoD PF09423.5 CBZ50273.1 - 8.9e-17 60.7 0.2 2.8e-16 59.1 0.2 1.6 1 1 0 1 1 1 1 PhoD-like phosphatase Mucin PF01456.12 CBZ50273.1 - 0.033 13.9 0.5 0.093 12.5 0.4 1.7 1 0 0 1 1 1 0 Mucin-like glycoprotein Prominin PF05478.6 CBZ50273.1 - 4.2 4.7 4.4 6.2 4.2 3.0 1.1 1 0 0 1 1 1 0 Prominin zf-HIT PF04438.11 CBZ50275.1 - 6.7e-07 28.8 10.4 1.2e-06 28.0 7.2 1.4 1 0 0 1 1 1 1 HIT zinc finger Ribosomal_60s PF00428.14 CBZ50275.1 - 0.0079 16.5 10.4 0.0079 16.5 7.2 6.1 5 2 1 6 6 6 1 60s Acidic ribosomal protein Methyltransf_23 PF13489.1 CBZ50276.1 - 1.2e-05 25.1 0.0 2.4e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 CBZ50276.1 - 0.0005 19.2 0.0 0.00083 18.5 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.9 CBZ50276.1 - 0.00095 18.5 0.0 0.0017 17.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.2 CBZ50276.1 - 0.0071 16.9 0.1 0.024 15.1 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 CBZ50276.1 - 0.0096 15.5 0.0 0.019 14.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 CBZ50276.1 - 0.027 14.0 0.0 0.046 13.2 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) zf-C2H2_2 PF12756.2 CBZ50276.1 - 0.04 14.0 0.6 0.083 13.0 0.4 1.4 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) CMAS PF02353.15 CBZ50276.1 - 0.045 12.8 0.0 0.07 12.2 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_26 PF13659.1 CBZ50276.1 - 0.075 13.0 0.0 0.16 12.0 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.7 CBZ50276.1 - 0.087 13.3 0.0 0.32 11.4 0.0 2.0 2 0 0 2 2 1 0 Methyltransferase domain Methyltransf_12 PF08242.7 CBZ50276.1 - 0.13 12.7 0.0 0.41 11.1 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain SDA1 PF05285.7 CBZ50276.1 - 3.2 6.9 13.8 0.11 11.7 2.1 2.1 2 0 0 2 2 2 0 SDA1 Sigma70_ner PF04546.8 CBZ50276.1 - 5.8 6.4 10.1 0.15 11.6 1.3 2.2 2 0 0 2 2 2 0 Sigma-70, non-essential region Peptidase_C13 PF01650.13 CBZ50278.1 - 1.2e-23 83.7 0.0 1.5e-23 83.4 0.0 1.1 1 0 0 1 1 1 1 Peptidase C13 family BIV_Env PF05858.7 CBZ50278.1 - 0.1 10.5 0.6 0.15 9.9 0.4 1.1 1 0 0 1 1 1 0 Bovine immunodeficiency virus surface protein (SU) Transglut_core PF01841.14 CBZ50279.1 - 0.0019 18.4 0.0 0.0025 18.0 0.0 1.3 1 1 0 1 1 1 1 Transglutaminase-like superfamily Usp PF00582.21 CBZ50279.1 - 0.1 12.8 0.1 0.13 12.4 0.1 1.3 1 0 0 1 1 1 0 Universal stress protein family HALZ PF02183.13 CBZ50280.1 - 8.5e-05 22.1 236.8 0.19 11.4 2.8 27.9 29 0 0 29 29 29 18 Homeobox associated leucine zipper Filament PF00038.16 CBZ50280.1 - 0.00018 21.0 0.2 0.00018 21.0 0.2 18.2 14 5 2 16 16 16 3 Intermediate filament protein DUF904 PF06005.7 CBZ50280.1 - 0.18 12.0 0.0 0.036 14.3 1.6 26.9 21 5 0 21 21 21 0 Protein of unknown function (DUF904) DivIC PF04977.10 CBZ50280.1 - 0.23 10.9 0.0 0.028 13.8 2.0 29.9 27 2 3 31 31 30 0 Septum formation initiator SPX PF03105.14 CBZ50280.1 - 0.27 11.0 0.0 0.27 11.0 0.0 8.9 5 3 1 6 6 6 0 SPX domain ELMO_CED12 PF04727.8 CBZ50282.1 - 1.9e-22 79.6 0.0 4.8e-22 78.3 0.0 1.7 1 1 0 1 1 1 1 ELMO/CED-12 family PRCH PF03967.8 CBZ50282.1 - 0.023 14.2 0.0 0.057 13.0 0.0 1.7 1 0 0 1 1 1 0 Photosynthetic reaction centre, H-chain N-terminal region Glyco_hydro_31 PF01055.21 CBZ50284.1 - 1.6e-131 439.2 0.5 2.1e-131 438.8 0.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 CBZ50284.1 - 5.2e-12 45.4 0.3 2.3e-11 43.3 0.1 2.2 2 0 0 2 2 2 1 Galactose mutarotase-like Actin PF00022.14 CBZ50285.1 - 1.9e-86 289.9 0.0 1.2e-77 260.9 0.0 3.1 2 1 0 2 2 2 2 Actin MreB_Mbl PF06723.8 CBZ50285.1 - 1.5e-05 23.7 0.1 0.11 11.0 0.0 2.8 3 0 0 3 3 3 2 MreB/Mbl protein WD40 PF00400.27 CBZ50286.1 - 2.6e-17 61.9 16.6 2.7e-06 27.0 0.0 6.5 7 1 0 7 7 7 4 WD domain, G-beta repeat eIF2A PF08662.6 CBZ50286.1 - 0.11 12.1 0.0 0.7 9.5 0.0 2.2 2 1 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A TatD_DNase PF01026.16 CBZ50287.1 - 1.1e-36 126.3 0.0 1.3e-36 126.1 0.0 1.1 1 0 0 1 1 1 1 TatD related DNase DUF162 PF02589.10 CBZ50287.1 - 0.12 11.8 0.0 3.7 7.0 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised ACR, YkgG family COG1556 tRNA_anti-codon PF01336.20 CBZ50288.1 - 0.0024 17.6 0.0 0.024 14.4 0.0 2.1 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain DEAD PF00270.24 CBZ50289.1 - 1.3e-38 132.1 0.0 4.3e-38 130.4 0.0 1.9 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CBZ50289.1 - 7.4e-26 89.8 0.1 1.9e-25 88.4 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 CBZ50289.1 - 1.4e-07 31.5 0.0 3.3e-07 30.2 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C_2 PF13307.1 CBZ50289.1 - 0.011 15.7 0.0 0.31 10.9 0.0 2.3 2 0 0 2 2 2 0 Helicase C-terminal domain AAA_22 PF13401.1 CBZ50289.1 - 0.017 15.2 0.2 0.1 12.7 0.1 2.3 2 1 0 2 2 2 0 AAA domain AAA_19 PF13245.1 CBZ50289.1 - 0.047 13.4 0.1 0.23 11.2 0.0 2.2 2 0 0 2 2 2 0 Part of AAA domain Kinesin PF00225.18 CBZ50291.1 - 5.2e-115 383.7 1.6 6.7e-115 383.3 1.1 1.1 1 0 0 1 1 1 1 Kinesin motor domain ResIII PF04851.10 CBZ50291.1 - 0.029 14.2 0.9 0.059 13.2 0.2 1.8 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit DUF2372 PF10178.4 CBZ50291.1 - 0.042 13.9 0.0 0.14 12.2 0.0 1.9 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2372) GMC_oxred_C PF05199.8 CBZ50292.1 - 2.7e-18 66.6 0.1 8e-18 65.1 0.1 1.8 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.14 CBZ50292.1 - 6.2e-08 32.1 0.0 4.5e-06 26.0 0.0 2.2 2 0 0 2 2 2 2 GMC oxidoreductase BC10 PF06726.7 CBZ50293.1 - 0.006 16.5 1.3 0.14 12.2 0.1 2.9 2 0 0 2 2 2 1 Bladder cancer-related protein BC10 GMC_oxred_C PF05199.8 CBZ50295.1 - 4e-17 62.8 0.0 9.4e-13 48.6 0.0 2.6 2 0 0 2 2 2 2 GMC oxidoreductase GMC_oxred_N PF00732.14 CBZ50295.1 - 9.7e-08 31.5 0.0 5.3e-07 29.0 0.0 2.2 3 0 0 3 3 3 1 GMC oxidoreductase Peptidase_M14 PF00246.19 CBZ50297.1 - 9.7e-22 77.8 0.0 1.8e-21 76.9 0.0 1.3 1 0 0 1 1 1 1 Zinc carboxypeptidase DUF4231 PF14015.1 CBZ50298.1 - 0.05 13.5 3.1 0.063 13.2 0.1 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF4231) tRNA-synt_1 PF00133.17 CBZ50299.1 - 6.4e-180 599.0 0.0 4.1e-179 596.4 0.0 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 CBZ50299.1 - 8.2e-37 126.3 0.7 2.8e-36 124.5 0.0 2.2 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 CBZ50299.1 - 8.5e-15 54.2 0.2 3e-06 26.1 0.0 4.1 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.1 CBZ50299.1 - 1.1e-08 34.5 0.5 3.8e-07 29.5 0.0 2.5 2 1 1 3 3 3 1 Leucyl-tRNA synthetase, Domain 2 Val_tRNA-synt_C PF10458.4 CBZ50299.1 - 4.9e-05 23.3 4.5 0.00012 22.0 3.1 1.7 1 0 0 1 1 1 1 Valyl tRNA synthetase tRNA binding arm tRNA-synt_1d PF00750.14 CBZ50299.1 - 0.00013 20.8 0.1 0.006 15.4 0.0 2.3 2 0 0 2 2 2 1 tRNA synthetases class I (R) tRNA-synt_1b PF00579.20 CBZ50299.1 - 0.018 14.1 0.1 0.13 11.3 0.0 2.2 2 0 0 2 2 2 0 tRNA synthetases class I (W and Y) tRNA-synt_1e PF01406.14 CBZ50299.1 - 0.021 13.9 0.0 0.26 10.3 0.0 2.2 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain tRNA-synt_1c PF00749.16 CBZ50299.1 - 0.026 13.1 0.0 0.24 10.0 0.0 2.4 3 0 0 3 3 3 0 tRNA synthetases class I (E and Q), catalytic domain Jag_N PF14804.1 CBZ50299.1 - 0.23 11.5 0.9 0.69 9.9 0.0 2.3 3 0 0 3 3 3 0 Jag N-terminus Cytochrom_C PF00034.16 CBZ50301.1 - 0.17 12.7 3.3 0.25 12.2 0.1 2.8 2 1 0 2 2 2 0 Cytochrome c Pkinase PF00069.20 CBZ50303.1 - 7.9e-07 28.4 0.0 6e-05 22.3 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.1 CBZ50303.1 - 0.00037 19.5 0.0 0.00058 18.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_Tyr PF07714.12 CBZ50303.1 - 0.0047 16.0 0.0 0.023 13.7 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase DUF4200 PF13863.1 CBZ50304.1 - 3e-22 78.8 25.6 3e-22 78.8 17.8 3.4 4 0 0 4 4 4 1 Domain of unknown function (DUF4200) USP8_interact PF08941.5 CBZ50304.1 - 0.27 10.5 2.3 0.58 9.4 0.9 2.2 2 0 0 2 2 2 0 USP8 interacting CheZ PF04344.8 CBZ50305.1 - 0.0054 16.4 4.9 0.0093 15.6 0.6 2.3 2 0 0 2 2 2 1 Chemotaxis phosphatase, CheZ SNARE PF05739.14 CBZ50305.1 - 0.011 15.4 3.5 0.011 15.4 2.4 2.7 3 0 0 3 3 3 0 SNARE domain Amnionless PF14828.1 CBZ50305.1 - 0.065 11.7 0.3 0.094 11.1 0.2 1.2 1 0 0 1 1 1 0 Amnionless DUF3675 PF12428.3 CBZ50305.1 - 0.13 12.5 0.2 0.13 12.5 0.1 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3675) Syntaxin-6_N PF09177.6 CBZ50305.1 - 0.34 11.3 7.3 0.13 12.7 0.5 2.4 2 0 0 2 2 2 0 Syntaxin 6, N-terminal Laminin_II PF06009.7 CBZ50305.1 - 0.87 9.3 6.9 0.84 9.3 1.1 2.4 2 1 0 2 2 2 0 Laminin Domain II DUF948 PF06103.6 CBZ50305.1 - 1.1 9.1 6.5 3.7 7.4 0.1 3.2 2 2 1 3 3 3 0 Bacterial protein of unknown function (DUF948) Syntaxin PF00804.20 CBZ50305.1 - 1.2 9.2 7.0 8.4 6.6 1.0 2.6 2 0 0 2 2 2 0 Syntaxin Hrs_helical PF12210.3 CBZ50305.1 - 1.9 8.7 7.3 0.11 12.8 0.6 2.2 2 1 1 3 3 3 0 Hepatocyte growth factor-regulated tyrosine kinase substrate FlgN PF05130.7 CBZ50305.1 - 2.3 8.4 15.9 0.13 12.4 1.1 2.8 2 1 1 3 3 3 0 FlgN protein ING PF12998.2 CBZ50305.1 - 5.5 7.3 9.3 0.98 9.7 0.3 2.7 3 0 0 3 3 3 0 Inhibitor of growth proteins N-terminal histone-binding TipAS PF07739.8 CBZ50305.1 - 9.9 6.5 7.5 7 7.0 0.4 2.9 2 1 0 2 2 2 0 TipAS antibiotic-recognition domain AP2 PF00847.15 CBZ50307.1 - 5.8e-10 39.1 0.0 1.1e-09 38.3 0.0 1.5 1 0 0 1 1 1 1 AP2 domain PRKCSH-like PF12999.2 CBZ50309.1 - 3.1e-13 49.6 5.7 1e-05 25.1 0.0 3.5 3 0 0 3 3 3 3 Glucosidase II beta subunit-like PRKCSH_1 PF13015.1 CBZ50309.1 - 2.5e-08 33.5 0.0 3.7e-07 29.7 0.0 2.2 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein PRKCSH PF07915.8 CBZ50309.1 - 0.054 14.3 0.0 0.27 12.0 0.0 2.3 1 0 0 1 1 1 0 Glucosidase II beta subunit-like protein PQ-loop PF04193.9 CBZ50311.1 - 3e-22 77.9 4.1 8.7e-11 41.2 0.1 2.2 2 0 0 2 2 2 2 PQ loop repeat MtN3_slv PF03083.11 CBZ50311.1 - 0.00089 19.0 1.7 0.068 13.0 0.1 2.3 1 1 1 2 2 2 2 Sugar efflux transporter for intercellular exchange Asn_synthase PF00733.16 CBZ50312.1 - 3.6e-74 249.5 0.0 4.8e-74 249.0 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.1 CBZ50312.1 - 1.9e-32 111.6 0.0 3.4e-32 110.8 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.1 CBZ50312.1 - 1.6e-20 73.4 0.0 1.5e-19 70.2 0.0 2.2 2 0 0 2 2 2 1 Glutamine amidotransferase domain DUF3700 PF12481.3 CBZ50312.1 - 1.9e-09 37.0 0.1 4.6e-09 35.8 0.1 1.6 1 0 0 1 1 1 1 Aluminium induced protein GATase_2 PF00310.16 CBZ50312.1 - 2.2e-06 26.6 0.0 0.044 12.5 0.0 3.1 1 1 2 3 3 3 3 Glutamine amidotransferases class-II tRNA_Me_trans PF03054.11 CBZ50312.1 - 0.0014 17.2 0.0 0.0023 16.5 0.0 1.2 1 0 0 1 1 1 1 tRNA methyl transferase NAD_synthase PF02540.12 CBZ50312.1 - 0.0015 17.5 0.0 0.0032 16.3 0.0 1.6 2 0 0 2 2 2 1 NAD synthase WD40 PF00400.27 CBZ50313.1 - 1.6e-13 49.9 18.0 0.0003 20.5 0.3 6.8 6 1 0 6 6 6 3 WD domain, G-beta repeat Pkinase PF00069.20 CBZ50314.1 - 3.6e-32 111.5 0.0 8.6e-17 61.1 0.0 3.4 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ50314.1 - 3e-10 39.6 0.0 0.0018 17.4 0.0 3.2 3 0 0 3 3 3 3 Protein tyrosine kinase zf-TFIIB PF13453.1 CBZ50315.1 - 0.04 13.0 0.5 0.083 12.0 0.4 1.5 1 0 0 1 1 1 0 Transcription factor zinc-finger IMCp PF12314.3 CBZ50316.1 - 5.8e-23 80.8 122.5 1.4e-13 50.7 13.0 7.1 1 1 5 6 6 6 4 Inner membrane complex protein DUF2399 PF09664.5 CBZ50317.1 - 3e-06 27.1 0.0 5.3e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function C-terminus (DUF2399) TP6A_N PF04406.9 CBZ50317.1 - 0.00016 21.2 0.2 0.00043 19.8 0.2 1.8 1 1 0 1 1 1 1 Type IIB DNA topoisomerase DUF2220 PF09983.4 CBZ50317.1 - 0.00017 20.7 0.0 0.00029 20.0 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria C-term(DUF2220) His_Phos_2 PF00328.17 CBZ50318.1 - 0.0015 17.9 0.0 9.9 5.3 0.0 3.3 3 0 0 3 3 3 3 Histidine phosphatase superfamily (branch 2) IFT57 PF10498.4 CBZ50319.1 - 4e-14 52.1 2.2 7.5e-09 34.8 2.9 2.2 2 0 0 2 2 2 2 Intra-flagellar transport protein 57 FlgN PF05130.7 CBZ50319.1 - 0.001 19.3 7.3 0.002 18.4 5.1 1.4 1 0 0 1 1 1 1 FlgN protein COG2 PF06148.6 CBZ50319.1 - 0.61 9.9 3.8 1.3 8.9 2.6 1.5 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 TPT PF03151.11 CBZ50320.1 - 1.2e-08 34.7 18.7 1.1e-05 25.1 8.4 2.3 2 0 0 2 2 2 2 Triose-phosphate Transporter family Nuc_sug_transp PF04142.10 CBZ50320.1 - 8.3e-07 28.3 0.6 2e-06 27.0 0.4 1.7 1 0 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.15 CBZ50320.1 - 6.5e-06 26.1 3.2 6.5e-06 26.1 2.2 3.1 2 2 0 2 2 2 1 EamA-like transporter family EmrE PF13536.1 CBZ50320.1 - 1.2e-05 25.4 4.5 1.2e-05 25.4 3.1 2.8 2 1 0 2 2 2 1 Multidrug resistance efflux transporter UAA PF08449.6 CBZ50320.1 - 0.0039 16.1 10.2 0.0057 15.6 7.1 1.2 1 0 0 1 1 1 1 UAA transporter family UPF0546 PF10639.4 CBZ50320.1 - 0.016 15.0 0.1 0.016 15.0 0.1 2.5 2 2 0 2 2 2 0 Uncharacterised protein family UPF0546 Multi_Drug_Res PF00893.14 CBZ50320.1 - 0.076 13.4 0.4 0.076 13.4 0.3 3.6 3 1 1 4 4 4 0 Small Multidrug Resistance protein DUF1129 PF06570.6 CBZ50320.1 - 0.13 11.5 2.4 0.18 11.0 1.2 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1129) DUF4181 PF13789.1 CBZ50320.1 - 0.23 11.4 3.5 0.19 11.6 0.2 2.4 2 2 0 2 2 2 0 Domain of unknown function (DUF4181) DUF4199 PF13858.1 CBZ50320.1 - 0.44 10.4 4.6 23 4.8 0.0 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF4199) U3_assoc_6 PF08640.6 CBZ50321.1 - 1.4e-13 50.3 2.1 1.4e-13 50.3 1.4 1.8 2 0 0 2 2 2 1 U3 small nucleolar RNA-associated protein 6 RNase_P_Rpp14 PF01900.14 CBZ50322.1 - 6.5e-14 51.7 0.0 8.2e-14 51.4 0.0 1.2 1 0 0 1 1 1 1 Rpp14/Pop5 family WD40 PF00400.27 CBZ50324.1 - 6e-07 29.1 3.9 0.00014 21.6 0.6 3.6 3 0 0 3 3 3 3 WD domain, G-beta repeat CENP-Q PF13094.1 CBZ50325.1 - 0.011 15.7 4.9 0.029 14.4 3.4 1.6 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Striatin PF08232.7 CBZ50325.1 - 0.027 14.7 4.7 0.14 12.4 3.2 2.3 1 0 0 1 1 1 0 Striatin family DivIC PF04977.10 CBZ50325.1 - 1.3 8.5 4.0 3.6 7.1 2.8 1.8 1 0 0 1 1 1 0 Septum formation initiator DUF4111 PF13427.1 CBZ50326.1 - 0.086 12.6 1.3 0.25 11.1 0.9 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4111) Pkinase PF00069.20 CBZ50327.1 - 6.2e-31 107.4 0.0 5.9e-09 35.4 0.0 4.1 4 0 0 4 4 4 3 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ50327.1 - 2.6e-07 29.9 0.0 0.0023 17.0 0.0 3.3 3 0 0 3 3 3 2 Protein tyrosine kinase APH PF01636.18 CBZ50327.1 - 0.0014 18.4 0.3 0.0033 17.1 0.2 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family Mito_fiss_reg PF05308.6 CBZ50327.1 - 0.066 12.5 9.7 0.18 11.1 0.8 2.9 2 0 0 2 2 2 0 Mitochondrial fission regulator NRDE-2 PF08424.5 CBZ50329.1 - 0.00057 18.8 0.0 0.0016 17.3 0.0 1.7 2 0 0 2 2 2 1 NRDE-2, necessary for RNA interference CTDII PF01556.13 CBZ50331.1 - 3.4e-20 71.7 1.5 3.3e-13 49.3 0.0 2.4 2 0 0 2 2 2 2 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 CBZ50331.1 - 2.1e-12 46.8 18.0 3.8e-12 46.0 12.4 1.4 1 0 0 1 1 1 1 DnaJ central domain DnaJ PF00226.26 CBZ50331.1 - 0.014 15.1 0.1 0.057 13.1 0.1 2.0 1 1 0 1 1 1 0 DnaJ domain Cytochrom_c3_2 PF14537.1 CBZ50331.1 - 0.99 9.7 4.6 1.9 8.8 3.2 1.4 1 0 0 1 1 1 0 Cytochrome c3 DUF1356 PF07092.7 CBZ50331.1 - 5.2 6.1 14.3 8.7 5.4 0.9 3.6 1 1 2 3 3 3 0 Protein of unknown function (DUF1356) DUF2353 PF09789.4 CBZ50332.1 - 0.00022 20.5 4.2 0.00025 20.3 2.9 1.1 1 0 0 1 1 1 1 Uncharacterized coiled-coil protein (DUF2353) Psu PF07455.6 CBZ50332.1 - 0.0026 17.2 1.5 0.0032 16.9 0.6 1.3 1 1 0 1 1 1 1 Phage polarity suppression protein (Psu) HAP1_N PF04849.8 CBZ50332.1 - 0.011 14.7 5.5 0.012 14.5 3.8 1.2 1 0 0 1 1 1 0 HAP1 N-terminal conserved region Prp19 PF08606.6 CBZ50332.1 - 0.02 14.6 0.5 0.02 14.6 0.3 1.8 2 0 0 2 2 1 0 Prp19/Pso4-like TMF_TATA_bd PF12325.3 CBZ50332.1 - 0.023 14.4 7.3 0.094 12.4 0.6 2.1 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF1465 PF07323.7 CBZ50332.1 - 0.034 13.7 0.7 0.058 12.9 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1465) GAS PF13851.1 CBZ50332.1 - 0.038 13.1 5.3 1.1 8.4 0.1 2.1 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding DUF3545 PF12065.3 CBZ50332.1 - 0.041 13.6 0.7 0.071 12.8 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3545) DUF1319 PF07028.6 CBZ50332.1 - 0.071 13.3 7.4 1.3 9.2 1.3 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1319) DUF948 PF06103.6 CBZ50332.1 - 0.29 11.0 1.7 7.3 6.5 0.1 2.3 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) APG6 PF04111.7 CBZ50332.1 - 0.59 9.1 8.5 2.4 7.1 5.9 1.8 1 1 0 1 1 1 0 Autophagy protein Apg6 DUF972 PF06156.8 CBZ50332.1 - 0.65 10.3 7.7 0.19 12.0 0.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Cortex-I_coil PF09304.5 CBZ50332.1 - 0.8 9.7 11.5 0.79 9.7 2.1 2.4 1 1 1 2 2 2 0 Cortexillin I, coiled coil TMF_DNA_bd PF12329.3 CBZ50332.1 - 0.89 9.4 6.9 1.2 8.9 0.4 2.4 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DivIC PF04977.10 CBZ50332.1 - 1 8.8 6.3 0.27 10.7 0.5 2.3 2 0 0 2 2 2 0 Septum formation initiator TPR_MLP1_2 PF07926.7 CBZ50332.1 - 2.7 7.7 8.5 4.8 6.9 3.6 2.3 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein ECM11 PF15463.1 CBZ50332.1 - 3 8.1 5.5 3.1 8.0 0.1 2.7 3 0 0 3 3 3 0 Extracellular mutant protein 11 DUF3450 PF11932.3 CBZ50332.1 - 3.1 6.9 6.6 7.3 5.7 0.6 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF3450) KLRAQ PF10205.4 CBZ50332.1 - 4.4 7.4 9.3 5.3 7.1 0.6 2.1 1 1 1 2 2 2 0 Predicted coiled-coil domain-containing protein IncA PF04156.9 CBZ50332.1 - 9.1 5.8 11.3 1.1e+02 2.2 7.8 2.0 1 1 0 1 1 1 0 IncA protein FAM74 PF15026.1 CBZ50333.1 - 0.015 14.9 1.0 0.028 14.0 0.7 1.3 1 0 0 1 1 1 0 FAM74 protein PsbM PF05151.7 CBZ50334.1 - 0.2 11.2 1.3 0.45 10.1 0.9 1.6 1 0 0 1 1 1 0 Photosystem II reaction centre M protein (PsbM) SDF PF00375.13 CBZ50335.1 - 0.0033 16.2 2.5 0.0041 15.9 1.7 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family MFS_1 PF07690.11 CBZ50336.1 - 2.4e-20 72.5 68.1 6.7e-18 64.5 15.5 2.9 2 1 1 3 3 3 3 Major Facilitator Superfamily Sugar_tr PF00083.19 CBZ50336.1 - 4.1e-14 51.9 34.1 2.5e-12 46.1 4.7 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter OATP PF03137.15 CBZ50336.1 - 0.012 13.7 22.7 0.13 10.2 0.7 4.1 3 1 1 4 4 4 0 Organic Anion Transporter Polypeptide (OATP) family DAGK_cat PF00781.19 CBZ50337.1 - 0.0089 15.4 0.0 1.6 8.2 0.0 3.1 3 0 0 3 3 3 1 Diacylglycerol kinase catalytic domain Cse1 PF08506.5 CBZ50338.1 - 2.7e-81 272.9 0.0 1.2e-80 270.8 0.0 2.1 2 1 0 2 2 2 1 Cse1 CAS_CSE1 PF03378.10 CBZ50338.1 - 1e-61 208.5 2.4 1.9e-61 207.6 1.6 1.4 1 0 0 1 1 1 1 CAS/CSE protein, C-terminus IBN_N PF03810.14 CBZ50338.1 - 2e-08 34.0 0.0 1.4e-07 31.2 0.0 2.6 2 0 0 2 2 2 1 Importin-beta N-terminal domain Arm PF00514.18 CBZ50338.1 - 0.054 13.3 5.3 29 4.6 0.1 5.0 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat Xpo1 PF08389.7 CBZ50338.1 - 0.19 11.6 7.7 0.37 10.6 0.0 4.2 5 1 0 5 5 5 0 Exportin 1-like protein TPR_11 PF13414.1 CBZ50339.1 - 0.039 13.5 3.9 0.68 9.6 0.2 2.9 2 1 0 2 2 2 0 TPR repeat TPR_2 PF07719.12 CBZ50339.1 - 0.14 12.1 4.2 1.4 8.9 0.4 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat PLU-1 PF08429.6 CBZ50340.1 - 9e-34 116.8 34.4 1.1e-16 60.7 0.0 8.6 6 2 2 8 8 8 6 PLU-1-like protein PHD PF00628.24 CBZ50340.1 - 0.015 14.9 0.6 0.076 12.7 0.0 2.5 2 0 0 2 2 2 0 PHD-finger PspB PF06667.7 CBZ50340.1 - 2.4 8.1 1.2 11 6.0 0.4 2.5 2 0 0 2 2 2 0 Phage shock protein B Collagen_bind_2 PF12904.2 CBZ50340.1 - 4 7.2 0.2 8.8 6.1 0.1 1.5 1 0 0 1 1 1 0 Putative collagen-binding domain of a collagenase Tweety PF04906.8 CBZ50340.1 - 7.5 4.8 0.5 16 3.8 0.4 1.4 1 0 0 1 1 1 0 Tweety GTP_cyclohydroI PF01227.17 CBZ50341.1 - 1.1e-65 220.2 0.1 1.6e-65 219.7 0.1 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.1 CBZ50341.1 - 0.028 14.3 0.0 0.052 13.4 0.0 1.4 1 0 0 1 1 1 0 QueF-like protein zf-CCCH PF00642.19 CBZ50342.1 - 5.5e-12 45.0 23.5 8.3e-07 28.5 3.6 3.8 4 0 0 4 4 4 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Ribosomal_L18e PF00828.14 CBZ50343.1 - 0.00037 20.8 0.0 0.00099 19.4 0.0 1.8 1 1 0 1 1 1 1 Ribosomal protein L18e/L15 FHA PF00498.21 CBZ50344.1 - 3.3e-05 23.9 0.0 0.14 12.2 0.0 2.4 2 0 0 2 2 2 2 FHA domain Macoilin PF09726.4 CBZ50344.1 - 6.4e-05 21.4 15.3 0.00013 20.4 10.6 1.4 1 0 0 1 1 1 1 Transmembrane protein Methyltransf_9 PF08003.6 CBZ50344.1 - 0.032 12.9 0.4 0.058 12.0 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) ERM PF00769.14 CBZ50344.1 - 0.06 12.8 35.8 0.55 9.7 8.9 2.5 1 1 1 2 2 2 0 Ezrin/radixin/moesin family Rab5-bind PF09311.6 CBZ50344.1 - 0.29 11.0 31.5 0.65 9.8 21.8 1.5 1 0 0 1 1 1 0 Rabaptin-like protein IncA PF04156.9 CBZ50344.1 - 1.2 8.7 33.5 5.2 6.6 23.2 1.9 1 1 0 1 1 1 0 IncA protein Peptidase_S49_N PF08496.5 CBZ50347.1 - 1.9 8.2 7.8 3.2 7.5 5.4 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal zf-CCHC_6 PF15288.1 CBZ50347.1 - 3.1 7.5 14.3 16 5.2 0.1 3.7 3 0 0 3 3 3 0 Zinc knuckle CAF-1_p150 PF11600.3 CBZ50347.1 - 6.2 6.1 34.9 0.012 14.9 7.5 3.4 3 0 0 3 3 3 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Pkinase PF00069.20 CBZ50348.1 - 9.6e-40 136.3 0.0 1e-36 126.4 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ50348.1 - 3.6e-39 134.3 0.0 7.9e-38 130.0 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.9 CBZ50348.1 - 0.024 13.7 0.0 0.22 10.5 0.0 2.1 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family SAM_2 PF07647.12 CBZ50348.1 - 0.29 10.9 0.0 0.65 9.8 0.0 1.5 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) ELO PF01151.13 CBZ50350.1 - 2.4e-50 171.1 19.1 3.9e-50 170.4 13.3 1.2 1 0 0 1 1 1 1 GNS1/SUR4 family Glyco_hydro_7 PF00840.15 CBZ50350.1 - 0.12 10.6 0.3 0.19 10.0 0.2 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 7 Peptidase_M16_C PF05193.16 CBZ50351.1 - 1.3e-28 99.9 0.0 4.9e-14 52.4 0.0 2.5 2 0 0 2 2 2 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 CBZ50351.1 - 5.4e-11 42.4 1.2 1.7e-10 40.8 0.4 2.2 2 1 0 2 2 2 1 Insulinase (Peptidase family M16) ALAD PF00490.16 CBZ50352.1 - 6.7e-139 462.2 0.2 8.2e-139 461.9 0.1 1.1 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase Nop14 PF04147.7 CBZ50352.1 - 0.025 12.5 1.8 0.034 12.0 1.3 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 CBZ50352.1 - 1.1 7.1 4.2 1.7 6.6 2.9 1.1 1 0 0 1 1 1 0 CDC45-like protein Daxx PF03344.10 CBZ50352.1 - 1.3 7.4 5.6 2.3 6.6 3.9 1.3 1 0 0 1 1 1 0 Daxx Family GCC2_GCC3 PF07699.8 CBZ50354.1 - 1.3e-12 47.1 310.7 0.00038 19.9 6.0 33.0 27 10 5 32 32 32 21 GCC2 and GCC3 GCC2_GCC3 PF07699.8 CBZ50355.1 - 4e-05 23.1 73.2 0.0005 19.6 2.3 8.0 5 2 2 7 7 7 5 GCC2 and GCC3 DUF4296 PF14129.1 CBZ50355.1 - 0.057 13.5 0.1 0.19 11.8 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4296) Pkinase PF00069.20 CBZ50356.1 - 2.3e-68 230.1 0.0 4.1e-68 229.3 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ50356.1 - 3.7e-32 111.4 0.0 4.5e-32 111.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBZ50356.1 - 4.1e-07 29.2 0.0 8.3e-05 21.6 0.0 2.1 1 1 1 2 2 2 2 Kinase-like Kdo PF06293.9 CBZ50356.1 - 0.00018 20.6 0.3 0.00035 19.7 0.0 1.5 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CBZ50356.1 - 0.021 14.5 0.1 0.075 12.7 0.1 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 CBZ50356.1 - 0.09 12.0 0.0 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL XAP5 PF04921.9 CBZ50357.1 - 5.1e-77 258.6 17.9 9.8e-77 257.7 9.0 2.7 1 1 1 2 2 2 1 XAP5, circadian clock regulator adh_short PF00106.20 CBZ50358.1 - 3e-11 43.5 5.7 3.4e-05 23.8 0.1 3.9 2 1 1 3 3 3 3 short chain dehydrogenase Nucleo_P87 PF07267.6 CBZ50360.1 - 6.7 5.2 0.2 11 4.5 0.1 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 DUF3322 PF11795.3 CBZ50361.1 - 0.047 13.3 2.2 0.089 12.4 1.5 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria N-term (DUF3322) BBS2_C PF14782.1 CBZ50361.1 - 0.42 9.1 3.8 0.63 8.5 2.6 1.2 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, C-terminal Peptidase_S28 PF05577.7 CBZ50362.1 - 1.3e-71 241.5 0.0 1.8e-71 241.0 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Abhydrolase_6 PF12697.2 CBZ50362.1 - 2.1e-08 34.3 3.8 8.1e-08 32.4 1.1 2.6 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CBZ50362.1 - 0.00015 21.5 0.1 0.00042 20.1 0.1 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family WD40 PF00400.27 CBZ50363.1 - 3.8e-11 42.4 10.2 0.045 13.6 0.2 6.5 7 0 0 7 7 7 5 WD domain, G-beta repeat zf-CDGSH PF09360.5 CBZ50364.1 - 1.5e-21 75.9 9.6 2.7e-14 52.7 2.6 2.3 2 0 0 2 2 2 2 Iron-binding zinc finger CDGSH type DUF4475 PF14753.1 CBZ50364.1 - 0.44 10.0 4.9 0.56 9.6 0.2 2.0 1 1 0 2 2 2 0 Domain of unknown function (DUF4475) OPA3 PF07047.7 CBZ50365.1 - 3.7e-32 110.8 0.2 4.8e-32 110.5 0.1 1.1 1 0 0 1 1 1 1 Optic atrophy 3 protein (OPA3) SAG PF04092.8 CBZ50366.1 - 3.6e-06 27.3 4.6 0.0017 18.7 3.2 2.4 1 1 0 1 1 1 1 SRS domain Trypan_PARP PF05887.6 CBZ50366.1 - 9.7e-06 25.4 14.4 1.9e-05 24.5 10.0 1.4 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) DUF4064 PF13273.1 CBZ50367.1 - 7.8 6.6 11.4 11 6.2 4.3 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF4064) Zip PF02535.17 CBZ50368.1 - 4e-20 72.0 1.5 1.3e-19 70.3 1.0 1.7 1 1 0 1 1 1 1 ZIP Zinc transporter Cyt-b5 PF00173.23 CBZ50369.1 - 1.2e-05 25.0 0.0 2.1e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain tRNA-synt_1b PF00579.20 CBZ50370.1 - 1.7e-30 106.1 0.0 1.7e-19 70.0 0.0 3.1 2 1 0 2 2 2 2 tRNA synthetases class I (W and Y) tRNA-synt_1f PF01921.13 CBZ50370.1 - 0.19 10.3 0.0 0.35 9.4 0.0 1.4 1 0 0 1 1 1 0 tRNA synthetases class I (K) Atg8 PF02991.11 CBZ50371.1 - 1.8e-34 117.8 0.4 4.5e-34 116.5 0.3 1.6 1 1 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.8 CBZ50371.1 - 5.6e-05 23.2 0.2 0.00022 21.3 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 DNA_RNApol_7kD PF03604.8 CBZ50373.1 - 4.3e-15 54.8 6.4 5.7e-15 54.4 4.4 1.2 1 0 0 1 1 1 1 DNA directed RNA polymerase, 7 kDa subunit GFA PF04828.9 CBZ50373.1 - 0.0057 16.5 1.8 1.1 9.2 0.0 2.1 1 1 1 2 2 2 2 Glutathione-dependent formaldehyde-activating enzyme DZR PF12773.2 CBZ50373.1 - 0.012 15.4 2.0 0.018 14.8 1.4 1.4 1 1 0 1 1 1 0 Double zinc ribbon HypA PF01155.14 CBZ50373.1 - 0.015 14.9 1.2 0.017 14.7 0.8 1.1 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family zf-dskA_traR PF01258.12 CBZ50373.1 - 0.054 13.2 3.7 0.083 12.6 2.5 1.3 1 0 0 1 1 1 0 Prokaryotic dksA/traR C4-type zinc finger DUF3279 PF11682.3 CBZ50373.1 - 0.11 12.1 1.1 2.3 7.8 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3279) zf-ISL3 PF14690.1 CBZ50373.1 - 0.13 12.2 0.2 0.13 12.2 0.2 2.0 2 0 0 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 Zn_Tnp_IS1595 PF12760.2 CBZ50373.1 - 0.59 9.9 5.9 0.6 9.9 0.2 2.1 1 1 1 2 2 2 0 Transposase zinc-ribbon domain Zn-ribbon_8 PF09723.5 CBZ50373.1 - 0.78 9.7 3.8 1.7 8.6 2.6 1.6 1 1 0 1 1 1 0 Zinc ribbon domain DUF2197 PF09963.4 CBZ50373.1 - 1.4 8.9 5.0 2 8.4 0.2 2.1 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2197) Zn_ribbon_recom PF13408.1 CBZ50373.1 - 2.8 8.2 6.4 3.6 7.9 0.5 2.1 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain Radial_spoke_3 PF06098.6 CBZ50376.1 - 2.9e-58 197.1 5.5 2.9e-58 197.1 3.8 2.2 1 1 0 2 2 2 1 Radial spoke protein 3 Pkinase PF00069.20 CBZ50377.1 - 2.4e-66 223.5 0.0 2.9e-66 223.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ50377.1 - 1.8e-39 135.3 0.0 2.2e-39 135.1 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBZ50377.1 - 1.4e-12 47.1 0.0 2.7e-12 46.2 0.0 1.4 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.9 CBZ50377.1 - 6.3e-10 38.4 0.1 1.1e-09 37.6 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CBZ50377.1 - 2.8e-07 30.5 0.0 0.00011 22.0 0.0 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.17 CBZ50377.1 - 4.8e-07 29.2 0.8 1.3e-05 24.6 0.7 2.0 1 1 1 2 2 2 2 RIO1 family Choline_kinase PF01633.15 CBZ50377.1 - 0.0014 18.2 0.1 0.0023 17.5 0.0 1.4 1 1 0 1 1 1 1 Choline/ethanolamine kinase HTH_Mga PF08280.6 CBZ50377.1 - 0.11 12.2 0.2 20 5.0 0.0 2.4 2 0 0 2 2 2 0 M protein trans-acting positive regulator (MGA) HTH domain tRNA-synt_2b PF00587.20 CBZ50378.1 - 7.8e-28 97.1 0.0 1.3e-27 96.5 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) RRM_1 PF00076.17 CBZ50379.1 - 2.5e-10 39.8 0.0 4.8e-10 38.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBZ50379.1 - 2.8e-08 33.6 0.0 5.7e-08 32.6 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) CSTF2_hinge PF14327.1 CBZ50379.1 - 4.6e-07 29.8 0.3 1e-06 28.7 0.2 1.5 1 0 0 1 1 1 1 Hinge domain of cleavage stimulation factor subunit 2 RRM_5 PF13893.1 CBZ50379.1 - 6.6e-05 22.6 0.0 0.0001 22.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CBZ50380.1 - 1.4e-06 27.8 0.0 2.7e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBZ50380.1 - 1.7e-06 27.9 0.0 2.9e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBZ50380.1 - 0.011 15.5 0.0 0.018 14.9 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PRELI PF04707.9 CBZ50382.1 - 1.1e-31 109.5 0.0 1.4e-31 109.2 0.0 1.1 1 0 0 1 1 1 1 PRELI-like family OSTMP1 PF09777.4 CBZ50382.1 - 0.068 12.3 0.0 0.1 11.7 0.0 1.2 1 0 0 1 1 1 0 Osteopetrosis-associated transmembrane protein 1 precursor UPF0203 PF05254.7 CBZ50383.1 - 0.029 14.2 0.3 1.9 8.3 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0203) Cmc1 PF08583.5 CBZ50383.1 - 0.051 13.3 0.1 1.1 9.0 0.0 2.3 2 0 0 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like Pet191_N PF10203.4 CBZ50383.1 - 0.24 11.4 2.1 0.91 9.6 1.4 1.8 1 1 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 CHCH PF06747.8 CBZ50383.1 - 1.1 9.2 3.1 2.9 7.9 0.5 2.2 2 0 0 2 2 2 0 CHCH domain PI3_PI4_kinase PF00454.22 CBZ50384.1 - 7.9e-09 35.3 0.0 8.3e-07 28.7 0.0 2.4 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.15 CBZ50384.1 - 1.8e-08 33.7 0.8 3e-08 33.0 0.6 1.3 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) TRAM_LAG1_CLN8 PF03798.11 CBZ50385.1 - 5e-21 75.1 9.2 5e-21 75.1 6.4 1.7 2 0 0 2 2 2 1 TLC domain RNA_pol_Rpb4 PF03874.11 CBZ50386.1 - 6.1e-09 35.9 0.5 5.8e-08 32.7 0.4 2.3 1 1 0 1 1 1 1 RNA polymerase Rpb4 CLAMP PF14769.1 CBZ50386.1 - 0.12 12.4 0.0 3.6 7.7 0.0 2.2 2 0 0 2 2 2 0 Flagellar C1a complex subunit C1a-32 Bul1_N PF04425.7 CBZ50388.1 - 1.1 7.7 0.0 1.8 7.0 0.0 1.2 1 0 0 1 1 1 0 Bul1 N terminus F-box PF00646.28 CBZ50389.1 - 6.2e-05 22.5 0.5 0.00024 20.6 0.1 2.1 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.2 CBZ50389.1 - 0.00029 20.4 1.5 0.00065 19.3 0.5 2.0 2 0 0 2 2 2 1 F-box-like Lipase_3 PF01764.20 CBZ50392.1 - 8.9e-09 35.0 0.0 1.5e-08 34.3 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) FSH1 PF03959.8 CBZ50392.1 - 0.11 11.9 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase (FSH1) CDC45 PF02724.9 CBZ50392.1 - 9.2 4.1 5.1 13 3.6 3.5 1.1 1 0 0 1 1 1 0 CDC45-like protein SAYSvFN PF10260.4 CBZ50393.1 - 6.1e-12 45.1 0.0 8.1e-12 44.7 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved domain (SAYSvFN) SEC-C PF02810.10 CBZ50393.1 - 2.6e-06 26.8 11.6 4.1e-06 26.1 8.0 1.2 1 0 0 1 1 1 1 SEC-C motif Glyco_hydro_81 PF03639.8 CBZ50394.1 - 6.7e-25 87.2 0.2 2.2e-24 85.5 0.0 1.8 2 1 0 2 2 2 1 Glycosyl hydrolase family 81 Kelch_4 PF13418.1 CBZ50394.1 - 0.019 14.7 0.0 0.058 13.1 0.0 1.8 1 0 0 1 1 1 0 Galactose oxidase, central domain Kinase-like PF14531.1 CBZ50395.1 - 1.1e-12 47.4 0.0 1.9e-12 46.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like CTP_transf_1 PF01148.15 CBZ50396.1 - 0.00012 21.8 5.0 0.00049 19.8 3.5 1.9 1 1 0 1 1 1 1 Cytidylyltransferase family Guanylate_cyc PF00211.15 CBZ50397.1 - 9.2e-77 256.5 0.1 2.9e-41 140.8 0.0 2.4 2 0 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain HAD PF12710.2 CBZ50397.1 - 8.8e-16 58.6 0.0 6e-11 42.8 0.0 2.7 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 CBZ50397.1 - 1.2e-14 55.2 0.1 2.7e-11 44.3 0.0 2.9 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 CBZ50397.1 - 3.7e-14 52.3 0.0 8.3e-14 51.1 0.0 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase_like2 PF13246.1 CBZ50397.1 - 3.9e-05 23.5 0.0 0.0001 22.1 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 CBZ50397.1 - 0.00036 20.2 0.0 0.0018 17.9 0.0 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Fn_bind PF02986.9 CBZ50397.1 - 0.29 10.6 7.7 0.025 14.1 0.8 2.6 2 0 0 2 2 2 0 Fibronectin binding repeat S6PP PF05116.8 CBZ50397.1 - 0.84 8.8 0.0 1.7 7.9 0.0 1.4 1 0 0 1 1 1 0 Sucrose-6F-phosphate phosphohydrolase Ribosomal_L11_N PF03946.9 CBZ50398.1 - 2.4e-20 71.7 0.0 3.5e-20 71.2 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.14 CBZ50398.1 - 7.2e-18 64.5 0.0 1.1e-17 63.9 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain NOC3p PF07540.6 CBZ50398.1 - 0.11 12.7 0.0 0.17 12.1 0.0 1.4 1 0 0 1 1 1 0 Nucleolar complex-associated protein CRAL_TRIO PF00650.15 CBZ50399.1 - 7.7e-23 80.7 0.1 1.1e-22 80.2 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.1 CBZ50399.1 - 4.4e-06 26.6 0.1 9e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Calc_CGRP_IAPP PF00214.14 CBZ50399.1 - 0.0028 17.6 0.1 0.0075 16.3 0.1 1.6 1 0 0 1 1 1 1 Calcitonin / CGRP / IAPP family DUF2188 PF09954.4 CBZ50399.1 - 7.2 6.6 6.8 1.1 9.2 1.3 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2188) Ribosomal_L2_C PF03947.13 CBZ50400.1 - 2.2e-50 169.7 0.3 4.4e-50 168.8 0.2 1.5 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 CBZ50400.1 - 1.4e-24 85.8 0.2 2.6e-24 84.9 0.1 1.5 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain SpoIIE PF07228.7 CBZ50401.1 - 2.2e-13 50.3 0.6 1.2e-12 47.9 0.4 1.9 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.1 CBZ50401.1 - 4.9e-09 35.9 0.1 6.9e-08 32.1 0.0 2.1 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C PF00481.16 CBZ50401.1 - 7.4e-06 25.5 0.0 0.0022 17.4 0.0 2.4 2 0 0 2 2 2 2 Protein phosphatase 2C Patatin PF01734.17 CBZ50402.1 - 0.0058 16.5 1.6 0.03 14.2 1.1 2.1 1 1 0 1 1 1 1 Patatin-like phospholipase PAN_4 PF14295.1 CBZ50403.1 - 1.8e-48 162.0 49.2 2.5e-09 36.6 1.1 7.8 8 0 0 8 8 8 7 PAN domain PAN_1 PF00024.21 CBZ50403.1 - 8.2e-48 160.0 52.8 2.5e-08 33.5 0.9 7.3 5 2 2 7 7 7 7 PAN domain PAN_2 PF08276.6 CBZ50403.1 - 0.094 12.5 46.2 0.32 10.8 0.5 7.4 7 0 0 7 7 7 0 PAN-like domain Ribosomal_L11_N PF03946.9 CBZ50404.1 - 1.5e-16 59.5 0.1 2.1e-16 59.0 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.14 CBZ50404.1 - 5.1e-13 48.9 0.1 7.9e-13 48.3 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain TM231 PF10149.4 CBZ50404.1 - 0.1 11.5 0.0 0.12 11.3 0.0 1.1 1 0 0 1 1 1 0 Transmembrane protein 231 eRF1_1 PF03463.10 CBZ50405.1 - 6.2e-40 135.8 0.1 9.3e-40 135.2 0.1 1.3 1 0 0 1 1 1 1 eRF1 domain 1 eRF1_3 PF03465.10 CBZ50405.1 - 6.5e-18 65.0 0.0 1.5e-17 63.8 0.0 1.7 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_2 PF03464.10 CBZ50405.1 - 8.4e-15 55.2 0.0 1.5e-14 54.4 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 2 XPA_C PF05181.7 CBZ50406.1 - 0.00058 19.3 0.0 0.0009 18.7 0.0 1.3 1 0 0 1 1 1 1 XPA protein C-terminus WD40 PF00400.27 CBZ50408.1 - 0.0007 19.3 0.0 0.016 15.0 0.1 2.9 3 1 0 3 3 3 1 WD domain, G-beta repeat Sel1 PF08238.7 CBZ50409.1 - 2.6e-22 78.7 17.6 0.047 14.3 0.1 11.2 10 1 1 11 11 11 7 Sel1 repeat DUF605 PF04652.11 CBZ50409.1 - 2.3e-05 23.9 22.1 2.3e-05 23.9 15.3 2.8 3 0 0 3 3 3 1 Vta1 like TPR_11 PF13414.1 CBZ50409.1 - 0.041 13.5 6.4 10 5.8 0.0 4.2 5 0 0 5 5 5 0 TPR repeat TPR_1 PF00515.23 CBZ50409.1 - 0.97 9.1 5.7 18 5.1 0.1 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_2 PF07719.12 CBZ50409.1 - 6.8 6.8 15.4 2.3 8.3 0.3 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat WD40 PF00400.27 CBZ50410.1 - 2.5e-07 30.3 0.4 0.4 10.6 0.0 5.3 5 0 0 5 5 5 3 WD domain, G-beta repeat Methyltransf_16 PF10294.4 CBZ50411.1 - 2.8e-17 62.7 0.0 2e-10 40.3 0.0 2.3 2 0 0 2 2 2 2 Putative methyltransferase Ank_2 PF12796.2 CBZ50411.1 - 8.6e-15 54.8 0.0 2.4e-11 43.8 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 CBZ50411.1 - 1.5e-12 46.6 0.3 0.00029 20.4 0.0 3.8 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.1 CBZ50411.1 - 4.9e-11 41.7 0.0 0.0052 16.8 0.0 4.1 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 CBZ50411.1 - 9.7e-10 38.7 0.1 2.4e-07 31.0 0.0 3.0 2 1 0 2 2 2 1 Ankyrin repeats (many copies) Ank_5 PF13857.1 CBZ50411.1 - 3.2e-08 33.5 0.7 0.00086 19.4 0.1 3.3 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Methyltransf_26 PF13659.1 CBZ50411.1 - 0.0034 17.4 0.0 0.055 13.5 0.0 2.6 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 CBZ50411.1 - 0.011 16.3 0.0 0.028 14.9 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 CBZ50411.1 - 0.1 11.9 0.0 0.19 11.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain PAXIP1_C PF15364.1 CBZ50411.1 - 0.18 11.7 2.4 8.2 6.3 0.2 2.7 2 0 0 2 2 2 0 PAXIP1-associated-protein-1 C term PTIP binding protein Prefoldin_2 PF01920.15 CBZ50412.1 - 2.7e-07 30.2 8.5 8.9e-07 28.6 5.9 1.9 1 1 0 1 1 1 1 Prefoldin subunit Striatin PF08232.7 CBZ50412.1 - 0.015 15.5 0.4 0.015 15.5 0.3 2.0 2 0 0 2 2 2 0 Striatin family CENP-Q PF13094.1 CBZ50412.1 - 0.043 13.8 4.7 2.1 8.3 0.7 2.2 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit YlqD PF11068.3 CBZ50412.1 - 0.058 13.4 11.7 0.61 10.1 0.6 2.1 2 0 0 2 2 2 0 YlqD protein Snf7 PF03357.16 CBZ50412.1 - 0.1 12.0 9.1 0.072 12.4 0.9 2.2 2 0 0 2 2 2 0 Snf7 Tropomyosin_1 PF12718.2 CBZ50412.1 - 0.14 11.9 5.5 0.21 11.4 3.8 1.2 1 0 0 1 1 1 0 Tropomyosin like TPR_MLP1_2 PF07926.7 CBZ50412.1 - 0.24 11.1 9.2 0.4 10.4 2.2 2.1 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Hormone_1 PF00103.15 CBZ50412.1 - 0.26 10.6 2.6 0.33 10.2 0.2 1.8 1 1 1 2 2 2 0 Somatotropin hormone family SseC PF04888.7 CBZ50412.1 - 0.43 9.8 9.1 0.56 9.4 6.3 1.1 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family Uds1 PF15456.1 CBZ50412.1 - 0.84 9.6 6.2 1.2 9.1 4.3 1.2 1 0 0 1 1 1 0 Up-regulated During Septation Viral_P18 PF04521.8 CBZ50412.1 - 1.3 8.4 9.4 3.7 7.0 0.3 2.6 2 1 0 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein Snapin_Pallidin PF14712.1 CBZ50412.1 - 1.3 9.3 8.1 0.62 10.4 0.3 2.5 2 1 0 2 2 2 0 Snapin/Pallidin Laminin_II PF06009.7 CBZ50412.1 - 1.7 8.3 11.6 0.8 9.4 1.9 2.1 1 1 1 2 2 2 0 Laminin Domain II Bacillus_HBL PF05791.6 CBZ50412.1 - 1.9 7.8 8.9 0.47 9.8 1.5 2.0 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) FliJ PF02050.11 CBZ50412.1 - 2.6 8.0 14.3 2.3 8.2 3.2 2.2 2 0 0 2 2 2 0 Flagellar FliJ protein HrpB7 PF09486.5 CBZ50412.1 - 3 7.7 15.2 1.7 8.5 2.5 2.3 1 1 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) WXG100 PF06013.7 CBZ50412.1 - 4.2 7.4 8.4 2.7 8.0 1.2 2.4 2 0 0 2 2 2 0 Proteins of 100 residues with WXG Spc24 PF08286.6 CBZ50412.1 - 5.5 6.7 6.3 3.5 7.3 0.7 2.1 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 DUF148 PF02520.12 CBZ50412.1 - 5.9 6.7 9.9 1 9.1 1.6 2.1 2 0 0 2 2 2 0 Domain of unknown function DUF148 GAS PF13851.1 CBZ50412.1 - 6.1 5.9 10.4 1.5 7.9 2.1 2.1 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding NTR2 PF15458.1 CBZ50412.1 - 6.4 5.9 12.4 0.61 9.2 2.3 2.1 1 1 1 2 2 2 0 Nineteen complex-related protein 2 CDP-OH_P_transf PF01066.16 CBZ50414.1 - 1e-11 45.0 0.2 2.1e-11 43.9 0.2 1.5 1 0 0 1 1 1 1 CDP-alcohol phosphatidyltransferase Bromodomain PF00439.20 CBZ50415.1 - 1.7e-24 85.5 0.1 3.4e-24 84.5 0.1 1.5 1 0 0 1 1 1 1 Bromodomain Acetyltransf_7 PF13508.1 CBZ50415.1 - 4.9e-10 39.4 1.3 9.1e-10 38.5 0.9 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 CBZ50415.1 - 1.3e-08 34.7 0.1 3.8e-08 33.2 0.1 1.9 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 CBZ50415.1 - 0.021 14.9 0.0 0.051 13.7 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.5 CBZ50415.1 - 0.022 14.4 0.1 0.078 12.7 0.0 2.0 2 0 0 2 2 2 0 FR47-like protein Acetyltransf_3 PF13302.1 CBZ50415.1 - 0.056 13.6 0.0 0.14 12.3 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 CBZ50415.1 - 0.08 12.7 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain UAA PF08449.6 CBZ50417.1 - 7.7e-69 231.9 19.9 9.4e-69 231.6 13.8 1.0 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.15 CBZ50417.1 - 6.6e-08 32.6 4.5 6.6e-08 32.6 3.1 3.3 2 1 0 3 3 3 2 EamA-like transporter family TPT PF03151.11 CBZ50417.1 - 3e-05 23.7 3.1 3e-05 23.7 2.2 2.9 2 1 0 2 2 2 1 Triose-phosphate Transporter family Nuc_sug_transp PF04142.10 CBZ50417.1 - 0.001 18.2 0.1 0.032 13.3 0.0 2.3 2 0 0 2 2 2 1 Nucleotide-sugar transporter DUF202 PF02656.10 CBZ50417.1 - 0.37 11.0 6.7 3.5 7.8 0.1 3.6 4 0 0 4 4 4 0 Domain of unknown function (DUF202) ubiquitin PF00240.18 CBZ50419.1 - 2.2e-23 81.4 0.5 2.4e-23 81.2 0.4 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 CBZ50419.1 - 2.5e-13 49.4 0.3 2.8e-13 49.3 0.2 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 CBZ50419.1 - 1.5e-05 25.1 0.1 4.7e-05 23.5 0.1 1.7 1 1 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.1 CBZ50419.1 - 0.00071 19.4 0.1 0.0014 18.4 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 CBZ50419.1 - 0.013 15.6 0.0 0.014 15.5 0.0 1.1 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain zf-Tim10_DDP PF02953.10 CBZ50420.1 - 3.6e-12 45.3 4.1 4.9e-12 44.9 2.9 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF842 PF05811.8 CBZ50420.1 - 0.031 13.7 3.3 0.041 13.3 2.3 1.2 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) TACI-CRD2 PF09305.5 CBZ50420.1 - 0.38 10.5 2.1 0.85 9.4 1.5 1.7 1 1 0 1 1 1 0 TACI, cysteine-rich domain Ribosomal_L39 PF00832.15 CBZ50421.1 - 1.9e-21 75.2 9.8 2.1e-21 75.0 6.8 1.0 1 0 0 1 1 1 1 Ribosomal L39 protein Pkinase PF00069.20 CBZ50422.1 - 1.1e-29 103.3 0.0 1.7e-17 63.4 0.0 2.9 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ50422.1 - 5.5e-12 45.3 0.4 2.1e-09 36.8 0.0 3.5 3 1 0 3 3 3 2 Protein tyrosine kinase APH PF01636.18 CBZ50422.1 - 0.023 14.4 0.0 0.089 12.5 0.0 2.0 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kinase-like PF14531.1 CBZ50422.1 - 0.11 11.4 0.0 2.3 7.1 0.0 2.2 2 0 0 2 2 2 0 Kinase-like DNA_pol_delta_4 PF04081.8 CBZ50423.1 - 1.5e-15 57.5 0.0 2.4e-15 56.8 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase delta, subunit 4 RRM_1 PF00076.17 CBZ50424.1 - 1.4e-12 47.0 0.0 2.1e-12 46.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBZ50424.1 - 2.4e-09 37.0 0.0 4.3e-09 36.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) zf-CCCH PF00642.19 CBZ50424.1 - 1.7e-06 27.5 0.7 3.7e-06 26.4 0.5 1.6 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_5 PF13893.1 CBZ50424.1 - 2.5e-06 27.2 0.0 5e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 CBZ50424.1 - 0.0014 18.4 0.0 0.0024 17.6 0.0 1.3 1 0 0 1 1 1 1 RNA binding motif Nup35_RRM_2 PF14605.1 CBZ50424.1 - 0.0014 18.3 0.0 0.0023 17.6 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Calcipressin PF04847.7 CBZ50424.1 - 0.034 13.7 0.0 0.054 13.0 0.0 1.3 1 0 0 1 1 1 0 Calcipressin zf-CCCH_2 PF14608.1 CBZ50424.1 - 0.17 11.9 1.3 0.46 10.5 0.9 1.8 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type FYVE PF01363.16 CBZ50424.1 - 0.66 9.9 5.6 0.31 10.9 2.0 1.9 2 1 0 2 2 2 0 FYVE zinc finger Abhydrolase_5 PF12695.2 CBZ50427.1 - 2.2e-25 89.1 0.0 1.9e-24 86.1 0.0 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CBZ50427.1 - 2.7e-18 66.6 5.0 1.1e-17 64.6 0.0 3.2 3 1 0 3 3 3 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 CBZ50427.1 - 1.3e-10 41.1 0.0 1.6e-06 27.7 0.0 3.0 3 0 0 3 3 3 2 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.8 CBZ50427.1 - 3e-07 30.2 0.0 6.6e-07 29.1 0.0 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold AXE1 PF05448.7 CBZ50427.1 - 4.1e-07 28.8 0.1 0.0077 14.7 0.0 2.4 1 1 1 2 2 2 2 Acetyl xylan esterase (AXE1) Abhydrolase_1 PF00561.15 CBZ50427.1 - 5.7e-07 29.3 0.0 0.00015 21.4 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 CBZ50427.1 - 3.7e-06 26.3 0.0 6.7e-06 25.4 0.0 1.4 1 1 0 1 1 1 1 Prolyl oligopeptidase family DUF2305 PF10230.4 CBZ50427.1 - 0.00098 18.6 0.0 0.055 12.8 0.0 2.1 1 1 1 2 2 2 1 Uncharacterised conserved protein (DUF2305) DUF818 PF05677.7 CBZ50427.1 - 0.0026 16.5 0.0 0.004 15.9 0.0 1.2 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) DLH PF01738.13 CBZ50427.1 - 0.0034 16.7 0.0 0.047 12.9 0.0 2.2 1 1 0 1 1 1 1 Dienelactone hydrolase family FSH1 PF03959.8 CBZ50427.1 - 0.013 14.9 0.0 0.021 14.2 0.0 1.4 1 0 0 1 1 1 0 Serine hydrolase (FSH1) BAAT_C PF08840.6 CBZ50427.1 - 0.017 14.8 0.0 2.8 7.5 0.0 2.4 1 1 1 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S15 PF02129.13 CBZ50427.1 - 0.019 14.4 0.0 0.31 10.4 0.0 2.2 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) DUF1201 PF06716.6 CBZ50427.1 - 0.13 12.1 0.7 0.27 11.0 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1201) Lipase_3 PF01764.20 CBZ50427.1 - 0.14 11.8 0.0 0.22 11.1 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Tropomyosin_1 PF12718.2 CBZ50428.1 - 0.61 9.9 6.1 0.19 11.5 2.1 1.6 2 0 0 2 2 2 0 Tropomyosin like DUF676 PF05057.9 CBZ50429.1 - 7.4e-33 113.6 0.0 1.2e-32 113.0 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) DUF3657 PF12394.3 CBZ50429.1 - 0.00026 20.9 0.0 0.00081 19.4 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF3657) PGAP1 PF07819.8 CBZ50429.1 - 0.046 13.2 0.0 0.074 12.6 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein Lipase_3 PF01764.20 CBZ50429.1 - 0.2 11.2 0.0 0.41 10.2 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) POP1 PF06978.6 CBZ50431.1 - 4.4e-31 108.0 17.4 4.4e-31 108.0 12.0 4.5 4 1 0 4 4 4 1 Ribonucleases P/MRP protein subunit POP1 POPLD PF08170.7 CBZ50431.1 - 1.8e-15 56.5 0.0 4.3e-15 55.3 0.0 1.7 1 0 0 1 1 1 1 POPLD (NUC188) domain PaaSYMP PF14738.1 CBZ50432.1 - 2.5e-09 37.0 10.2 2.5e-09 37.0 7.1 3.5 3 2 1 4 4 4 1 Solute carrier (proton/amino acid symporter), TRAMD3 or PAT1 Flavodoxin_5 PF12724.2 CBZ50432.1 - 0.23 11.4 1.6 0.31 11.0 0.1 2.0 2 1 0 2 2 2 0 Flavodoxin domain VASP_tetra PF08776.6 CBZ50432.1 - 0.57 9.5 4.7 0.22 10.8 0.8 2.1 2 0 0 2 2 2 0 VASP tetramerisation domain DUF4392 PF14336.1 CBZ50433.1 - 2.7e-46 157.6 0.0 3.3e-46 157.4 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4392) Metallophos PF00149.23 CBZ50434.1 - 1.8e-08 34.0 0.5 3.8e-08 32.9 0.2 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase FBPase_2 PF06874.6 CBZ50434.1 - 0.0035 15.4 0.1 0.32 8.9 0.0 2.1 2 0 0 2 2 2 2 Firmicute fructose-1,6-bisphosphatase Hepar_II_III PF07940.8 CBZ50434.1 - 0.03 14.1 0.0 0.073 12.9 0.0 1.6 1 0 0 1 1 1 0 Heparinase II/III-like protein GvpL_GvpF PF06386.6 CBZ50435.1 - 0.067 12.7 0.3 0.082 12.4 0.2 1.1 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF GvpK PF05121.7 CBZ50436.1 - 2.1 8.2 7.6 0.66 9.8 0.5 2.6 2 0 0 2 2 2 0 Gas vesicle protein K Complex1_LYR_1 PF13232.1 CBZ50437.1 - 0.0042 17.2 0.7 0.006 16.7 0.5 1.4 1 0 0 1 1 1 1 Complex1_LYR-like DUF4240 PF14024.1 CBZ50437.1 - 0.09 12.6 0.1 0.14 12.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4240) Glutaredoxin2_C PF04399.8 CBZ50437.1 - 0.11 12.0 0.1 0.14 11.7 0.1 1.1 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain Complex1_LYR PF05347.10 CBZ50437.1 - 0.15 11.8 0.6 0.27 11.0 0.4 1.5 1 0 0 1 1 1 0 Complex 1 protein (LYR family) FAST_1 PF06743.10 CBZ50438.1 - 0.031 14.0 1.9 0.26 11.0 0.0 3.1 3 0 0 3 3 3 0 FAST kinase-like protein, subdomain 1 Methyltransf_16 PF10294.4 CBZ50440.1 - 0.0061 16.0 0.0 8 5.8 0.0 3.3 3 0 0 3 3 3 2 Putative methyltransferase DNA_ligase_IV PF11411.3 CBZ50440.1 - 0.08 12.7 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 DNA ligase IV RRM_1 PF00076.17 CBZ50441.1 - 2e-07 30.5 0.0 3.6e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBZ50441.1 - 3.9e-05 23.5 0.0 8.3e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Spore_coat_CotO PF14153.1 CBZ50441.1 - 6.9e-05 22.3 10.0 6.9e-05 22.3 6.9 3.0 3 1 0 3 3 3 1 Spore coat protein CotO RRM_5 PF13893.1 CBZ50441.1 - 0.00014 21.6 0.0 0.00023 20.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ycf1 PF05758.7 CBZ50441.1 - 5.1 4.6 20.2 0.019 12.7 4.8 2.1 2 0 0 2 2 2 0 Ycf1 TPR_12 PF13424.1 CBZ50442.1 - 4.9e-12 45.6 19.0 2.3e-06 27.4 2.7 3.7 3 1 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 CBZ50442.1 - 4.9e-10 38.5 18.5 0.0023 17.7 1.3 4.9 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_1 PF00515.23 CBZ50442.1 - 2.4e-08 33.2 13.0 0.00046 19.6 1.2 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.1 CBZ50442.1 - 5.6e-08 32.3 16.5 1.2e-07 31.2 3.9 3.6 3 0 0 3 3 3 1 TPR repeat TPR_7 PF13176.1 CBZ50442.1 - 9.4e-07 28.1 16.1 0.034 13.9 0.3 4.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 CBZ50442.1 - 0.0072 16.9 24.2 1.5 9.6 3.0 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.1 CBZ50442.1 - 0.074 12.8 5.8 2.2 8.2 0.2 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF3107 PF11305.3 CBZ50442.1 - 0.12 12.2 0.0 0.25 11.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3107) Daxx PF03344.10 CBZ50442.1 - 0.15 10.5 10.8 0.2 10.1 7.5 1.1 1 0 0 1 1 1 0 Daxx Family TPR_6 PF13174.1 CBZ50442.1 - 0.19 12.2 0.1 0.19 12.2 0.1 3.9 4 0 0 4 4 3 0 Tetratricopeptide repeat FLO_LFY PF01698.11 CBZ50442.1 - 0.19 10.5 6.1 1 8.1 3.8 2.0 2 0 0 2 2 2 0 Floricaula / Leafy protein Collagen PF01391.13 CBZ50442.1 - 0.55 9.8 14.0 1.1 8.9 9.7 1.4 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies) TPR_14 PF13428.1 CBZ50442.1 - 0.74 10.6 16.5 14 6.6 0.3 5.1 3 1 2 5 5 5 0 Tetratricopeptide repeat TPR_10 PF13374.1 CBZ50442.1 - 3 7.8 25.0 0.054 13.4 0.6 5.0 6 0 0 6 6 6 0 Tetratricopeptide repeat Nop14 PF04147.7 CBZ50442.1 - 5.1 4.8 13.3 7.2 4.3 9.2 1.1 1 0 0 1 1 1 0 Nop14-like family Prefoldin_2 PF01920.15 CBZ50443.1 - 0.0068 16.1 0.8 0.0068 16.1 0.5 2.4 3 0 0 3 3 3 1 Prefoldin subunit AAA_23 PF13476.1 CBZ50443.1 - 0.3 11.3 5.0 0.063 13.5 0.6 1.8 2 0 0 2 2 2 0 AAA domain DUF2205 PF10224.4 CBZ50443.1 - 0.59 9.7 4.7 0.27 10.8 0.2 2.7 3 0 0 3 3 3 0 Predicted coiled-coil protein (DUF2205) TerD PF02342.13 CBZ50445.1 - 1.5e-15 56.9 0.0 2.4e-15 56.3 0.0 1.2 1 0 0 1 1 1 1 TerD domain Melibiase PF02065.13 CBZ50446.1 - 6.4e-09 34.9 0.0 1.1e-08 34.2 0.0 1.2 1 0 0 1 1 1 1 Melibiase CRAL_TRIO PF00650.15 CBZ50447.1 - 7.3e-08 32.0 0.0 1e-07 31.5 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain Proteasome PF00227.21 CBZ50448.1 - 3.5e-37 127.5 0.1 3.9e-37 127.4 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Cyclin_C PF02984.14 CBZ50449.1 - 0.0038 17.1 0.7 0.025 14.5 0.0 2.7 3 0 0 3 3 3 1 Cyclin, C-terminal domain MIF4G PF02854.14 CBZ50452.1 - 1.9e-30 105.8 3.7 2.5e-30 105.4 2.5 1.1 1 0 0 1 1 1 1 MIF4G domain Bac_GDH PF05088.7 CBZ50452.1 - 0.12 9.7 0.4 0.2 8.9 0.3 1.2 1 0 0 1 1 1 0 Bacterial NAD-glutamate dehydrogenase MA3 PF02847.12 CBZ50452.1 - 0.38 10.4 0.2 1.2 8.9 0.0 1.8 2 0 0 2 2 2 0 MA3 domain DUF4138 PF13595.1 CBZ50452.1 - 4.9 6.0 0.5 7.4 5.4 0.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4138) Methyltransf_15 PF09445.5 CBZ50453.1 - 3.5e-23 81.9 0.0 2e-22 79.4 0.0 2.1 1 1 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_25 PF13649.1 CBZ50453.1 - 0.014 15.7 0.4 0.032 14.5 0.3 1.6 1 0 0 1 1 1 0 Methyltransferase domain Daxx PF03344.10 CBZ50454.1 - 0.44 8.9 24.0 1 7.7 16.6 1.6 1 0 0 1 1 1 0 Daxx Family Herpes_LMP1 PF05297.6 CBZ50455.1 - 1.1 8.1 9.8 2 7.2 6.8 1.3 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) F-box-like PF12937.2 CBZ50459.1 - 6.7e-09 35.3 0.6 3.3e-08 33.1 0.4 2.3 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 CBZ50459.1 - 1.4e-07 30.9 1.1 3.7e-07 29.6 0.4 2.1 2 0 0 2 2 2 1 F-box domain PQQ_2 PF13360.1 CBZ50459.1 - 0.0024 17.3 0.0 0.01 15.3 0.0 1.9 2 0 0 2 2 2 1 PQQ-like domain Elongin_A PF06881.6 CBZ50459.1 - 0.075 13.4 0.2 0.19 12.1 0.1 1.6 1 0 0 1 1 1 0 RNA polymerase II transcription factor SIII (Elongin) subunit A CTP_synth_N PF06418.9 CBZ50461.1 - 7.2e-120 399.2 0.1 1e-119 398.7 0.1 1.2 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.23 CBZ50461.1 - 1.7e-45 154.8 0.0 2.6e-45 154.2 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 CBZ50461.1 - 5.6e-08 32.4 0.0 1.7e-07 30.9 0.0 1.8 1 1 1 2 2 2 1 Peptidase C26 CbiA PF01656.18 CBZ50461.1 - 2.7e-05 23.6 0.0 4.3e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain Acetyltransf_5 PF13444.1 CBZ50461.1 - 0.0026 18.2 0.1 0.0058 17.1 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain ArgK PF03308.11 CBZ50461.1 - 0.0028 16.4 0.7 0.0049 15.6 0.5 1.3 1 0 0 1 1 1 1 ArgK protein TRAPP PF04051.11 CBZ50462.1 - 2.9e-33 114.5 0.0 3.5e-33 114.2 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component zf-B_box PF00643.19 CBZ50463.1 - 3.1e-10 39.7 19.8 2.1e-07 30.6 4.4 4.3 4 1 0 4 4 4 2 B-box zinc finger zf-RING_5 PF14634.1 CBZ50463.1 - 0.0049 16.5 3.2 0.0049 16.5 2.2 3.8 3 1 0 3 3 3 1 zinc-RING finger domain DDHD PF02862.12 CBZ50463.1 - 3.6 7.3 11.5 6.9 6.3 8.0 1.6 1 0 0 1 1 1 0 DDHD domain Pox_Ag35 PF03286.9 CBZ50463.1 - 5.1 6.5 16.5 9.2 5.7 11.4 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein zf-UBR PF02207.15 CBZ50463.1 - 5.2 6.8 27.1 0.046 13.4 2.0 3.6 3 1 0 3 3 3 0 Putative zinc finger in N-recognin (UBR box) Daxx PF03344.10 CBZ50463.1 - 6.9 5.0 38.3 11 4.3 26.6 1.3 1 0 0 1 1 1 0 Daxx Family DUF913 PF06025.7 CBZ50463.1 - 9.9 4.7 6.3 15 4.2 4.4 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Longin PF13774.1 CBZ50464.1 - 5.1e-09 35.5 0.0 9e-09 34.7 0.0 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.16 CBZ50464.1 - 1.4e-07 30.9 0.4 2.1e-07 30.4 0.3 1.3 1 0 0 1 1 1 1 Synaptobrevin AAA PF00004.24 CBZ50465.1 - 2.8e-30 105.2 0.1 6.6e-24 84.6 0.0 2.6 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 CBZ50465.1 - 0.00055 19.9 4.2 0.0099 15.8 0.1 3.1 2 1 1 3 3 3 1 AAA ATPase domain TIP49 PF06068.8 CBZ50465.1 - 0.00055 18.7 0.1 0.0011 17.7 0.1 1.4 1 1 0 1 1 1 1 TIP49 C-terminus AAA_22 PF13401.1 CBZ50465.1 - 0.0012 19.0 0.1 0.062 13.4 0.1 2.8 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 CBZ50465.1 - 0.0043 16.1 0.0 0.028 13.4 0.0 2.0 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 CBZ50465.1 - 0.0057 17.4 0.4 0.016 16.0 0.0 2.0 2 1 0 2 2 1 1 AAA domain AAA_19 PF13245.1 CBZ50465.1 - 0.015 15.0 4.2 0.026 14.2 0.7 2.9 2 1 1 3 3 3 0 Part of AAA domain IstB_IS21 PF01695.12 CBZ50465.1 - 0.015 14.7 0.0 0.024 14.0 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein Sigma54_activat PF00158.21 CBZ50465.1 - 0.017 14.6 0.0 0.03 13.8 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_5 PF07728.9 CBZ50465.1 - 0.018 14.7 0.3 0.12 12.0 0.2 2.2 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) T2SE PF00437.15 CBZ50465.1 - 0.038 12.8 0.0 0.062 12.2 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_2 PF07724.9 CBZ50465.1 - 0.054 13.4 0.0 0.2 11.5 0.0 1.9 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) PhoH PF02562.11 CBZ50465.1 - 0.054 12.7 0.0 0.086 12.0 0.0 1.2 1 0 0 1 1 1 0 PhoH-like protein ResIII PF04851.10 CBZ50465.1 - 0.055 13.2 0.1 0.16 11.7 0.0 1.7 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Pox_Ag35 PF03286.9 CBZ50465.1 - 6.8 6.1 8.7 2.4 7.6 0.9 2.1 2 0 0 2 2 2 0 Pox virus Ag35 surface protein RabGAP-TBC PF00566.13 CBZ50466.1 - 1e-39 136.2 0.7 4.4e-34 117.8 0.0 2.6 3 0 0 3 3 3 2 Rab-GTPase-TBC domain AP2 PF00847.15 CBZ50467.1 - 2.6e-11 43.5 6.5 1.7e-06 28.0 0.3 2.6 2 0 0 2 2 2 2 AP2 domain Spore_III_AB PF09548.5 CBZ50468.1 - 0.71 9.6 0.0 1.5 8.5 0.0 1.5 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) Rhabdo_ncap PF00945.13 CBZ50468.1 - 6.2 5.2 0.2 14 4.1 0.2 1.5 1 0 0 1 1 1 0 Rhabdovirus nucleocapsid protein CLPTM1 PF05602.7 CBZ50469.1 - 5.8e-30 104.3 2.3 2e-27 95.9 1.2 2.6 2 1 0 2 2 2 2 Cleft lip and palate transmembrane protein 1 (CLPTM1) Gemini_mov PF01708.11 CBZ50470.1 - 0.95 9.0 1.3 4.6 6.8 0.9 2.2 1 0 0 1 1 1 0 Geminivirus putative movement protein VTC PF09359.5 CBZ50471.1 - 1.2e-130 434.5 0.0 2.2e-130 433.7 0.0 1.4 1 0 0 1 1 1 1 VTC domain DUF202 PF02656.10 CBZ50471.1 - 1.2e-08 35.0 0.9 3.1e-08 33.7 0.6 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF202) SPX PF03105.14 CBZ50471.1 - 0.00066 19.5 0.0 0.00066 19.5 0.0 2.5 3 0 0 3 3 3 1 SPX domain PK PF00224.16 CBZ50472.1 - 1.4e-86 290.2 0.1 7.8e-48 162.8 0.6 3.1 3 0 0 3 3 3 3 Pyruvate kinase, barrel domain HpcH_HpaI PF03328.9 CBZ50472.1 - 1.9e-05 23.7 2.0 0.0002 20.3 0.3 2.9 2 1 1 3 3 3 1 HpcH/HpaI aldolase/citrate lyase family AMMECR1 PF01871.12 CBZ50472.1 - 0.015 14.4 0.0 0.027 13.6 0.0 1.3 1 0 0 1 1 1 0 AMMECR1 PK_C PF02887.11 CBZ50472.1 - 0.13 11.8 0.5 3.2 7.3 0.2 2.5 2 0 0 2 2 2 0 Pyruvate kinase, alpha/beta domain Methyltransf_28 PF02636.12 CBZ50473.1 - 0.081 12.3 0.1 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Baculo_p24 PF05073.7 CBZ50473.1 - 0.29 10.6 2.6 0.39 10.2 0.5 1.9 2 0 0 2 2 2 0 Baculovirus P24 capsid protein GAS PF13851.1 CBZ50473.1 - 1.3 8.1 16.9 0.37 9.9 3.2 2.3 1 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding Na_H_Exchanger PF00999.16 CBZ50474.1 - 2.4e-45 154.7 42.7 4e-45 153.9 29.6 1.3 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Ribosomal_L22 PF00237.14 CBZ50475.1 - 1.2e-30 105.5 0.2 1.9e-30 104.9 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e GPI2 PF06432.6 CBZ50476.1 - 1.2e-79 267.6 14.0 1.4e-79 267.4 9.7 1.0 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase DUF1440 PF07274.7 CBZ50476.1 - 0.012 15.6 1.4 0.019 14.9 0.0 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF1440) PspB PF06667.7 CBZ50476.1 - 0.094 12.6 0.4 0.22 11.4 0.2 1.6 1 0 0 1 1 1 0 Phage shock protein B RRM_2 PF04059.7 CBZ50477.1 - 1.8e-31 107.9 0.4 2.6e-31 107.4 0.3 1.2 1 0 0 1 1 1 1 RNA recognition motif 2 RRM_1 PF00076.17 CBZ50477.1 - 0.093 12.3 0.1 0.17 11.5 0.1 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AP2 PF00847.15 CBZ50478.1 - 4.1e-09 36.4 1.0 8e-09 35.5 0.7 1.5 1 0 0 1 1 1 1 AP2 domain ACDC PF14733.1 CBZ50478.1 - 5.1e-07 29.7 0.1 1.1e-06 28.6 0.0 1.6 1 1 0 1 1 1 1 AP2-coincident C-terminal L6_membrane PF05805.7 CBZ50479.1 - 0.15 11.5 0.0 0.28 10.7 0.0 1.4 1 0 0 1 1 1 0 L6 membrane protein NAD_binding_1 PF00175.16 CBZ50480.1 - 2.9e-17 63.1 0.0 5.3e-17 62.3 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 CBZ50480.1 - 6e-05 23.1 0.0 0.00013 22.0 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain FAD_binding_1 PF00667.15 CBZ50480.1 - 0.34 10.3 0.9 0.97 8.8 0.0 2.2 3 0 0 3 3 3 0 FAD binding domain PseudoU_synth_2 PF00849.17 CBZ50481.1 - 2.7e-22 79.3 0.3 2.3e-11 43.7 0.1 2.6 2 1 0 2 2 2 2 RNA pseudouridylate synthase PGBA_C PF15437.1 CBZ50481.1 - 0.00067 19.7 8.0 0.0016 18.5 5.5 1.6 1 0 0 1 1 1 1 Plasminogen-binding protein pgbA C-terminal LSM PF01423.17 CBZ50482.1 - 4.3e-18 64.6 0.0 5.8e-18 64.1 0.0 1.1 1 0 0 1 1 1 1 LSM domain AAA_13 PF13166.1 CBZ50483.1 - 0.47 8.8 7.9 0.62 8.4 5.5 1.0 1 0 0 1 1 1 0 AAA domain Atg14 PF10186.4 CBZ50483.1 - 0.62 8.9 6.4 0.9 8.4 4.4 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF4463 PF14703.1 CBZ50483.1 - 4.2 7.9 8.9 12 6.5 0.1 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4463) Phage_GP20 PF06810.6 CBZ50483.1 - 4.9 6.5 12.5 0.41 10.0 4.9 1.8 2 0 0 2 2 2 0 Phage minor structural protein GP20 5_3_exonuc PF01367.15 CBZ50483.1 - 5.4 7.3 6.8 7.9 6.7 3.2 2.3 2 1 0 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold GDI PF00996.13 CBZ50484.1 - 5.6e-26 90.8 0.0 1.2e-07 30.4 0.0 4.1 4 0 0 4 4 4 4 GDP dissociation inhibitor FAD_oxidored PF12831.2 CBZ50484.1 - 3.8e-06 26.2 0.3 6.2e-06 25.5 0.2 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 CBZ50484.1 - 8.4e-05 22.5 0.8 0.00026 20.9 0.6 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 CBZ50484.1 - 0.0038 17.6 0.3 0.0075 16.6 0.2 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 CBZ50484.1 - 0.0052 15.9 0.1 0.0099 14.9 0.0 1.3 1 0 0 1 1 1 1 Thi4 family GIDA PF01134.17 CBZ50484.1 - 0.071 11.9 0.7 0.11 11.2 0.5 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Lycopene_cycl PF05834.7 CBZ50484.1 - 0.13 11.1 0.2 0.22 10.4 0.2 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Abhydrolase_1 PF00561.15 CBZ50486.1 - 7.7e-19 68.1 0.0 6.9e-18 65.0 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 CBZ50486.1 - 4.2e-15 56.2 0.0 6e-15 55.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 CBZ50486.1 - 1.7e-05 24.3 0.0 2.8e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Abhydrolase_5 PF12695.2 CBZ50486.1 - 0.00064 19.5 0.2 0.012 15.3 0.1 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 CBZ50486.1 - 0.03 13.5 0.0 1.2 8.2 0.0 2.3 2 0 0 2 2 2 0 Prolyl oligopeptidase family DUF2048 PF09752.4 CBZ50486.1 - 0.1 11.4 0.0 0.15 10.9 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2048) LIP PF03583.9 CBZ50486.1 - 0.14 11.3 0.1 7.2 5.7 0.0 2.1 2 0 0 2 2 2 0 Secretory lipase AP2 PF00847.15 CBZ50489.1 - 1.6e-13 50.5 1.7 5e-13 48.9 1.2 1.9 1 0 0 1 1 1 1 AP2 domain SNAP PF14938.1 CBZ50490.1 - 1.1e-11 44.4 10.1 1.8e-11 43.6 7.0 1.5 1 1 0 1 1 1 1 Soluble NSF attachment protein, SNAP TRP_2 PF08344.6 CBZ50490.1 - 0.014 15.2 0.0 0.052 13.4 0.0 2.0 1 0 0 1 1 1 0 Transient receptor ion channel II TPR_12 PF13424.1 CBZ50490.1 - 0.016 15.1 4.3 3 7.8 0.1 3.1 2 2 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.1 CBZ50490.1 - 0.22 11.1 4.1 8 6.1 0.2 3.1 2 1 0 2 2 2 0 TPR repeat Vps16_C PF04840.7 CBZ50492.1 - 1e-49 169.2 0.0 1.4e-49 168.7 0.0 1.1 1 0 0 1 1 1 1 Vps16, C-terminal region Vps16_N PF04841.8 CBZ50492.1 - 2.8e-49 167.7 0.0 4.1e-48 163.9 0.0 2.1 1 1 0 1 1 1 1 Vps16, N-terminal region Pro_isomerase PF00160.16 CBZ50494.1 - 6.9e-52 175.7 0.4 1.4e-51 174.7 0.3 1.6 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.27 CBZ50494.1 - 1.6e-11 43.5 6.1 0.0026 17.6 0.3 4.5 4 0 0 4 4 4 4 WD domain, G-beta repeat Choline_kinase PF01633.15 CBZ50495.1 - 2.2e-43 148.3 0.0 9.6e-23 80.8 0.0 2.1 2 0 0 2 2 2 2 Choline/ethanolamine kinase APH PF01636.18 CBZ50495.1 - 5e-15 55.8 2.0 1e-13 51.6 1.4 2.8 2 1 0 2 2 2 1 Phosphotransferase enzyme family TGT PF01702.13 CBZ50496.1 - 1.4e-57 194.6 0.0 1.3e-52 178.5 0.0 2.1 1 1 1 2 2 2 2 Queuine tRNA-ribosyltransferase SAC3_GANP PF03399.11 CBZ50497.1 - 0.0023 17.4 0.0 0.0044 16.6 0.0 1.3 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family CSD PF00313.17 CBZ50498.1 - 4.4e-23 80.8 1.3 6.7e-23 80.2 0.9 1.3 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain OB_RNB PF08206.6 CBZ50498.1 - 0.00051 19.4 0.2 0.001 18.5 0.2 1.6 1 1 0 1 1 1 1 Ribonuclease B OB domain FAST_1 PF06743.10 CBZ50499.1 - 0.041 13.5 6.0 15 5.4 0.1 5.8 5 1 1 6 6 6 0 FAST kinase-like protein, subdomain 1 Glyco_hydro_35 PF01301.14 CBZ50500.1 - 2.6e-23 82.8 0.0 4.8e-23 82.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 Peptidase_M49 PF03571.10 CBZ50500.1 - 2.2 6.2 0.0 3.2 5.6 0.0 1.1 1 0 0 1 1 1 0 Peptidase family M49 GTP_EFTU PF00009.22 CBZ50501.1 - 2.4e-46 157.5 0.0 2.8e-46 157.3 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 CBZ50501.1 - 1.3e-19 70.2 0.1 5.3e-19 68.2 0.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 CBZ50501.1 - 5.7e-08 32.7 0.5 5e-07 29.7 0.1 2.3 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 CBZ50501.1 - 0.00057 19.8 0.0 0.0015 18.5 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase PAM2 PF07145.10 CBZ50501.1 - 0.0047 16.3 1.6 0.0071 15.7 0.2 2.0 2 0 0 2 2 2 1 Ataxin-2 C-terminal region G-alpha PF00503.15 CBZ50501.1 - 0.01 14.5 0.0 0.016 13.9 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit Dioxygenase_N PF04444.9 CBZ50501.1 - 0.13 12.2 0.0 0.3 11.0 0.0 1.5 1 0 0 1 1 1 0 Catechol dioxygenase N terminus p25-alpha PF05517.7 CBZ50502.1 - 9.8e-43 146.0 0.8 1.1e-42 145.9 0.5 1.0 1 0 0 1 1 1 1 p25-alpha DUF3669 PF12417.3 CBZ50505.1 - 0.0063 16.2 0.4 71 3.2 0.0 4.5 4 1 1 5 5 5 3 Zinc finger protein Patched PF02460.13 CBZ50508.1 - 1.2e-84 284.7 16.2 8.4e-41 139.7 0.0 3.1 2 1 1 3 3 3 3 Patched family Sterol-sensing PF12349.3 CBZ50508.1 - 2.3e-31 108.3 0.4 2.3e-31 108.3 0.3 3.1 4 0 0 4 4 4 2 Sterol-sensing domain of SREBP cleavage-activation ACR_tran PF00873.14 CBZ50508.1 - 0.0057 14.1 21.6 0.009 13.4 15.0 1.2 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family APC2 PF08672.6 CBZ50508.1 - 0.14 12.3 0.0 0.4 10.9 0.0 1.7 1 0 0 1 1 1 0 Anaphase promoting complex (APC) subunit 2 NAGidase PF07555.8 CBZ50508.1 - 0.16 10.8 0.0 0.31 9.8 0.0 1.3 1 0 0 1 1 1 0 beta-N-acetylglucosaminidase SecD_SecF PF02355.11 CBZ50508.1 - 0.25 10.5 20.7 0.055 12.6 10.9 2.2 2 0 0 2 2 2 0 Protein export membrane protein Lactamase_B_2 PF12706.2 CBZ50509.1 - 7.5e-30 103.9 0.5 1.2e-29 103.3 0.4 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 CBZ50509.1 - 6.3e-11 42.2 0.0 1.1e-10 41.4 0.0 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 CBZ50509.1 - 0.0021 17.7 1.5 0.015 14.9 0.2 2.4 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily Ras PF00071.17 CBZ50510.1 - 7.1e-46 155.5 0.0 1.6e-34 118.6 0.0 2.1 2 0 0 2 2 2 2 Ras family Miro PF08477.8 CBZ50510.1 - 5.6e-16 59.1 0.0 7.7e-15 55.4 0.0 2.1 1 1 0 1 1 1 1 Miro-like protein Arf PF00025.16 CBZ50510.1 - 7.1e-09 35.1 0.0 4.4e-07 29.2 0.0 2.1 2 0 0 2 2 2 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 CBZ50510.1 - 1.4e-06 27.8 0.0 2.4e-06 27.1 0.0 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 CBZ50510.1 - 4.5e-05 22.7 0.0 0.00021 20.5 0.0 1.9 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 CBZ50510.1 - 0.0036 17.2 0.0 0.0072 16.2 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase YqhR PF11085.3 CBZ50511.1 - 0.072 12.6 0.2 0.1 12.1 0.1 1.2 1 0 0 1 1 1 0 Conserved membrane protein YqhR ABC_membrane PF00664.18 CBZ50512.1 - 4.2e-56 190.3 17.4 5.5e-29 101.4 3.4 3.4 3 0 0 3 3 3 3 ABC transporter transmembrane region ABC_tran PF00005.22 CBZ50512.1 - 3.6e-49 166.5 0.0 1.1e-30 106.6 0.0 2.9 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 CBZ50512.1 - 7.6e-09 35.1 0.0 0.09 11.9 0.1 3.8 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 CBZ50512.1 - 2.9e-07 29.9 1.9 0.014 14.8 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.1 CBZ50512.1 - 7.5e-07 29.3 0.2 0.0066 16.4 0.0 3.8 3 1 0 3 3 3 1 AAA domain AAA_25 PF13481.1 CBZ50512.1 - 2.8e-05 23.6 0.7 0.1 12.0 0.1 2.5 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.18 CBZ50512.1 - 3.8e-05 23.6 0.0 0.06 13.3 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase DUF87 PF01935.12 CBZ50512.1 - 7.7e-05 22.6 0.9 0.046 13.5 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function DUF87 DUF258 PF03193.11 CBZ50512.1 - 0.00022 20.4 0.1 0.7 9.0 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 Miro PF08477.8 CBZ50512.1 - 0.0003 21.2 0.0 0.38 11.2 0.0 2.7 2 0 0 2 2 2 1 Miro-like protein AAA_22 PF13401.1 CBZ50512.1 - 0.00081 19.5 0.1 3 7.9 0.0 3.5 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.1 CBZ50512.1 - 0.0011 18.9 4.3 0.17 11.8 0.0 3.3 3 0 0 3 3 3 2 AAA ATPase domain cobW PF02492.14 CBZ50512.1 - 0.0022 17.4 1.0 0.25 10.7 0.0 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain FtsK_SpoIIIE PF01580.13 CBZ50512.1 - 0.003 17.0 1.4 0.61 9.5 0.0 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family T2SE PF00437.15 CBZ50512.1 - 0.005 15.7 0.7 1.6 7.5 0.0 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_33 PF13671.1 CBZ50512.1 - 0.03 14.2 0.1 9.4 6.1 0.0 2.9 2 0 0 2 2 2 0 AAA domain Adeno_IVa2 PF02456.10 CBZ50512.1 - 0.03 13.0 0.2 0.34 9.4 0.1 2.0 2 0 0 2 2 2 0 Adenovirus IVa2 protein AAA_10 PF12846.2 CBZ50512.1 - 0.035 13.5 1.3 7.6 5.8 0.4 2.6 2 0 0 2 2 2 0 AAA-like domain ArgK PF03308.11 CBZ50512.1 - 0.054 12.2 0.5 0.17 10.6 0.0 1.9 2 0 0 2 2 2 0 ArgK protein AAA_17 PF13207.1 CBZ50512.1 - 0.068 13.9 1.1 12 6.7 0.0 3.1 2 0 0 2 2 2 0 AAA domain TrwB_AAD_bind PF10412.4 CBZ50512.1 - 0.071 11.7 0.7 0.98 7.9 0.0 2.3 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AAA_18 PF13238.1 CBZ50512.1 - 0.097 12.9 0.9 2.9 8.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain MobB PF03205.9 CBZ50512.1 - 0.12 12.1 1.5 5.3 6.7 0.0 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_23 PF13476.1 CBZ50512.1 - 0.76 10.0 12.1 1 9.6 0.1 3.2 3 0 0 3 3 3 0 AAA domain Dynamin_N PF00350.18 CBZ50512.1 - 3.8 7.2 6.4 7.4 6.3 0.0 2.7 3 0 0 3 3 2 0 Dynamin family RRS1 PF04939.7 CBZ50513.1 - 3.1e-37 127.5 7.0 3.1e-37 127.5 4.8 3.0 2 1 0 2 2 2 1 Ribosome biogenesis regulatory protein (RRS1) CMD PF02627.15 CBZ50513.1 - 0.037 13.8 0.5 0.098 12.5 0.1 1.9 2 0 0 2 2 2 0 Carboxymuconolactone decarboxylase family LXG PF04740.7 CBZ50513.1 - 0.2 11.4 5.0 0.18 11.5 1.1 2.1 2 0 0 2 2 2 0 LXG domain of WXG superfamily Exonuc_VII_L PF02601.10 CBZ50513.1 - 0.38 9.8 6.0 0.54 9.4 4.2 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit XRN_N PF03159.13 CBZ50514.1 - 5.2e-23 81.6 0.0 8.6e-12 44.9 0.0 4.0 4 0 0 4 4 4 2 XRN 5'-3' exonuclease N-terminus MIF4G PF02854.14 CBZ50515.1 - 3.9e-19 68.9 1.3 6e-19 68.2 0.0 1.9 2 0 0 2 2 2 1 MIF4G domain MA3 PF02847.12 CBZ50515.1 - 3.6e-15 55.6 1.2 6.9e-15 54.7 0.9 1.5 1 0 0 1 1 1 1 MA3 domain SNF2_N PF00176.18 CBZ50516.1 - 5.9e-64 215.7 0.0 3.8e-40 137.5 0.0 2.5 1 1 1 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.26 CBZ50516.1 - 3.3e-14 52.4 0.1 1.5e-13 50.3 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 CBZ50516.1 - 1.2e-11 43.9 0.1 2.7e-11 42.8 0.1 1.5 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 SnAC PF14619.1 CBZ50516.1 - 8.9e-11 41.8 2.1 8.9e-11 41.8 1.5 6.0 7 1 0 7 7 7 1 Snf2-ATP coupling, chromatin remodelling complex HSA PF07529.8 CBZ50516.1 - 1.5 8.6 20.0 0.53 10.0 7.8 3.4 2 0 0 2 2 2 0 HSA Nucleoside_tran PF01733.13 CBZ50519.1 - 0.00064 18.9 13.9 0.15 11.1 0.5 4.8 4 1 0 4 4 4 4 Nucleoside transporter FA_desaturase PF00487.19 CBZ50519.1 - 3.9 6.8 8.3 20 4.5 5.8 2.2 1 1 0 1 1 1 0 Fatty acid desaturase Folate_rec PF03024.9 CBZ50520.1 - 0.00075 19.1 1.8 0.0015 18.2 1.3 1.4 1 0 0 1 1 1 1 Folate receptor family SAG PF04092.8 CBZ50521.1 - 3.9e-57 192.0 22.0 5.7e-33 113.9 4.1 2.1 2 0 0 2 2 2 2 SRS domain YebF PF13995.1 CBZ50521.1 - 0.029 14.3 0.3 0.17 11.9 0.0 2.5 2 1 0 3 3 3 0 YebF-like protein SAG PF04092.8 CBZ50522.1 - 9e-55 184.3 15.5 1.6e-33 115.7 2.6 2.1 2 0 0 2 2 2 2 SRS domain SAG PF04092.8 CBZ50523.1 - 2.8e-53 179.5 19.1 4.5e-33 114.2 3.0 2.1 2 0 0 2 2 2 2 SRS domain SAG PF04092.8 CBZ50524.1 - 5.3e-56 188.3 15.6 6.4e-34 117.0 2.6 2.1 2 0 0 2 2 2 2 SRS domain SAG PF04092.8 CBZ50525.1 - 1e-55 187.3 20.7 1.2e-32 112.9 3.3 2.2 2 0 0 2 2 2 2 SRS domain SAG PF04092.8 CBZ50526.1 - 4.8e-55 185.2 19.6 6.7e-32 110.4 3.4 2.1 2 0 0 2 2 2 2 SRS domain SAG PF04092.8 CBZ50527.1 - 1.2e-51 174.2 20.7 3.5e-31 108.1 3.8 2.2 2 0 0 2 2 2 2 SRS domain DUF3277 PF11681.3 CBZ50527.1 - 0.019 14.4 0.3 0.045 13.2 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3277) SAG PF04092.8 CBZ50528.1 - 1.1e-51 174.3 26.0 2.2e-31 108.8 4.5 2.1 2 0 0 2 2 2 2 SRS domain NARG2_C PF10505.4 CBZ50528.1 - 0.034 13.3 0.2 1.3 8.1 0.0 2.4 3 0 0 3 3 3 0 NMDA receptor-regulated gene protein 2 C-terminus CHB_HEX_C PF03174.8 CBZ50528.1 - 0.092 12.5 1.1 0.17 11.7 0.0 1.9 2 0 0 2 2 2 0 Chitobiase/beta-hexosaminidase C-terminal domain SAG PF04092.8 CBZ50529.1 - 2e-59 199.4 23.4 1.8e-32 112.3 2.1 2.1 2 0 0 2 2 2 2 SRS domain SAG PF04092.8 CBZ50530.1 - 4.3e-55 185.3 26.8 6e-34 117.0 6.9 2.4 2 0 0 2 2 2 2 SRS domain Stomoxyn PF11585.3 CBZ50530.1 - 6.4 6.6 6.6 15 5.4 4.6 1.7 1 0 0 1 1 1 0 Insect antimicrobial peptide, stomoxyn SAG PF04092.8 CBZ50531.1 - 1.6e-51 173.8 20.4 4.9e-32 110.9 4.1 2.1 2 0 0 2 2 2 2 SRS domain DUF3277 PF11681.3 CBZ50531.1 - 0.015 14.7 0.1 0.043 13.3 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3277) WD40 PF00400.27 CBZ50532.1 - 3.6e-50 166.1 8.1 2.1e-11 43.2 0.0 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat Prp19 PF08606.6 CBZ50532.1 - 1.3e-28 98.5 4.1 1.3e-28 98.5 2.9 2.1 2 0 0 2 2 2 1 Prp19/Pso4-like Nup160 PF11715.3 CBZ50532.1 - 0.0001 20.6 0.1 0.041 12.0 0.0 2.9 3 0 0 3 3 3 2 Nucleoporin Nup120/160 U-box PF04564.10 CBZ50532.1 - 0.0023 17.8 0.0 0.005 16.7 0.0 1.5 1 0 0 1 1 1 1 U-box domain zf-Nse PF11789.3 CBZ50532.1 - 0.005 16.3 0.1 0.012 15.0 0.1 1.7 1 1 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit Nbas_N PF15492.1 CBZ50532.1 - 0.053 12.6 0.0 6 5.8 0.0 2.3 1 1 1 2 2 2 0 Neuroblastoma-amplified sequence, N terminal Rieske PF00355.21 CBZ50533.1 - 3.7e-15 55.2 0.1 7.1e-15 54.3 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain UCR_TM PF02921.9 CBZ50533.1 - 5.1e-05 23.4 0.0 9.7e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 Ubiquinol cytochrome reductase transmembrane region SAG PF04092.8 CBZ50534.1 - 1.6e-57 193.2 25.1 6.1e-34 117.0 5.4 2.2 2 0 0 2 2 2 2 SRS domain SAG PF04092.8 CBZ50535.1 - 2.2e-53 179.8 23.6 2.2e-33 115.2 6.0 2.3 2 0 0 2 2 2 2 SRS domain SAG PF04092.8 CBZ50536.1 - 4.8e-58 194.9 25.1 1.2e-32 112.9 3.1 2.2 2 0 0 2 2 2 2 SRS domain SAG PF04092.8 CBZ50537.1 - 1.2e-49 167.7 32.0 2e-32 112.1 6.8 3.1 2 1 0 2 2 2 2 SRS domain Stomoxyn PF11585.3 CBZ50537.1 - 5.8 6.8 6.6 15 5.5 4.6 1.7 1 0 0 1 1 1 0 Insect antimicrobial peptide, stomoxyn SAG PF04092.8 CBZ50538.1 - 1.1e-53 180.8 22.2 1.3e-31 109.5 4.7 2.2 2 0 0 2 2 2 2 SRS domain SAG PF04092.8 CBZ50539.1 - 6e-47 159.0 16.5 3e-29 101.9 3.7 2.2 2 0 0 2 2 2 2 SRS domain DUF3277 PF11681.3 CBZ50539.1 - 0.067 12.6 1.4 0.17 11.3 0.1 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3277) GTP_EFTU PF00009.22 CBZ50541.1 - 3.1e-22 78.9 0.0 1.2e-16 60.6 0.0 2.2 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 CBZ50541.1 - 3.1e-12 46.5 0.0 5.4e-12 45.7 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain ATP_bind_1 PF03029.12 CBZ50541.1 - 0.00036 20.1 0.0 0.092 12.2 0.0 2.2 2 0 0 2 2 2 2 Conserved hypothetical ATP binding protein PduV-EutP PF10662.4 CBZ50541.1 - 0.0055 16.2 0.0 1.5 8.3 0.0 3.0 2 1 1 3 3 3 1 Ethanolamine utilisation - propanediol utilisation MobB PF03205.9 CBZ50541.1 - 0.033 13.8 0.2 0.065 12.9 0.1 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B GTP_EFTU_D2 PF03144.20 CBZ50541.1 - 0.059 13.4 0.0 0.17 12.0 0.0 1.8 1 0 0 1 1 1 0 Elongation factor Tu domain 2 Miro PF08477.8 CBZ50541.1 - 0.063 13.7 0.1 0.15 12.6 0.0 1.6 1 0 0 1 1 1 0 Miro-like protein Dynamin_N PF00350.18 CBZ50541.1 - 0.14 11.9 0.1 0.25 11.1 0.1 1.4 1 0 0 1 1 1 0 Dynamin family UCR_hinge PF02320.11 CBZ50542.1 - 4.7e-20 71.2 2.9 5.6e-20 71.0 2.0 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase hinge protein TSP_1 PF00090.14 CBZ50542.1 - 0.093 12.8 3.1 0.44 10.7 0.2 2.1 1 1 1 2 2 2 0 Thrombospondin type 1 domain Cmc1 PF08583.5 CBZ50542.1 - 0.21 11.3 2.8 0.32 10.8 1.9 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like DUF3469 PF11952.3 CBZ50543.1 - 5.1e-07 29.2 0.3 6.4e-07 28.9 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3469) Cytomega_gL PF01801.11 CBZ50543.1 - 0.12 11.8 0.0 0.14 11.6 0.0 1.1 1 0 0 1 1 1 0 Cytomegalovirus glycoprotein L HIT PF01230.18 CBZ50544.1 - 8.5e-23 80.7 0.0 1.2e-22 80.2 0.0 1.2 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 CBZ50544.1 - 2.6e-08 34.0 0.0 3.8e-08 33.5 0.0 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding PCNA_N PF00705.13 CBZ50545.1 - 6.1e-25 87.1 0.3 1.1e-24 86.3 0.2 1.4 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, N-terminal domain Rad9 PF04139.8 CBZ50545.1 - 3.8e-06 26.2 0.0 7.6e-06 25.2 0.0 1.5 1 1 0 1 1 1 1 Rad9 PCNA_C PF02747.10 CBZ50545.1 - 0.00012 21.9 0.0 0.00022 21.1 0.0 1.4 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, C-terminal domain RRM_1 PF00076.17 CBZ50546.1 - 1.5e-46 155.8 0.0 6.4e-17 60.9 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBZ50546.1 - 3.2e-37 126.3 0.0 3.4e-12 46.1 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBZ50546.1 - 9.5e-27 92.6 0.0 9.8e-12 44.5 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1866 PF08952.6 CBZ50546.1 - 8.6e-07 28.5 0.0 0.029 13.9 0.0 3.2 3 0 0 3 3 3 2 Domain of unknown function (DUF1866) Limkain-b1 PF11608.3 CBZ50546.1 - 0.0039 16.9 0.1 0.059 13.1 0.0 2.3 2 0 0 2 2 2 1 Limkain b1 Nup35_RRM_2 PF14605.1 CBZ50546.1 - 0.025 14.3 0.0 7.7 6.3 0.0 2.5 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif RNA_bind PF08675.6 CBZ50546.1 - 0.062 13.2 0.1 9.2 6.3 0.0 2.8 3 0 0 3 3 3 0 RNA binding domain YkyB PF14177.1 CBZ50546.1 - 0.44 10.6 0.0 16 5.6 0.0 2.2 2 0 0 2 2 2 0 YkyB-like protein MAT1 PF06391.8 CBZ50549.1 - 3.2e-14 52.9 10.6 4.6e-14 52.4 7.3 1.3 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 TRAP-gamma PF07074.7 CBZ50549.1 - 1.6 8.2 4.2 2.8 7.4 2.9 1.3 1 0 0 1 1 1 0 Translocon-associated protein, gamma subunit (TRAP-gamma) DnaJ PF00226.26 CBZ50550.1 - 1e-06 28.3 0.0 3.5e-06 26.6 0.0 1.8 1 0 0 1 1 1 1 DnaJ domain DUF2562 PF10814.3 CBZ50550.1 - 0.21 11.5 0.1 0.21 11.5 0.0 2.7 3 1 1 4 4 4 0 Protein of unknown function (DUF2562) Ribosomal_L18p PF00861.17 CBZ50551.1 - 1.9e-39 134.5 0.2 1.9e-39 134.5 0.1 1.8 2 0 0 2 2 2 1 Ribosomal L18p/L5e family Ribosomal_L18_c PF14204.1 CBZ50551.1 - 1.8e-35 121.3 7.2 1.8e-35 121.3 5.0 1.8 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region PA28_beta PF02252.13 CBZ50551.1 - 0.019 14.4 0.3 0.044 13.2 0.2 1.6 1 0 0 1 1 1 0 Proteasome activator pa28 beta subunit CHORD PF04968.7 CBZ50552.1 - 5.6e-54 180.2 21.1 4.6e-27 94.0 6.5 2.2 2 0 0 2 2 2 2 CHORD TMA7 PF09072.5 CBZ50552.1 - 0.057 13.8 0.5 0.093 13.2 0.4 1.3 1 0 0 1 1 1 0 Translation machinery associated TMA7 BTK PF00779.14 CBZ50552.1 - 0.46 10.1 11.4 9.5 5.9 4.6 3.3 2 1 0 2 2 2 0 BTK motif MFS_1 PF07690.11 CBZ50554.1 - 6.8e-16 57.9 11.3 1.2e-15 57.0 7.9 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF2431 PF10354.4 CBZ50555.1 - 8.3e-06 25.8 0.0 1.2e-05 25.3 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF2431) DapB_C PF05173.9 CBZ50555.1 - 0.098 12.4 0.5 0.16 11.7 0.3 1.3 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, C-terminus Stm1_N PF09598.5 CBZ50555.1 - 0.57 10.9 10.2 2.8 8.7 7.0 2.2 1 0 0 1 1 1 0 Stm1 Ribosomal_L35p PF01632.14 CBZ50556.1 - 0.0025 17.6 2.9 0.0025 17.6 2.0 1.7 1 1 1 2 2 2 1 Ribosomal protein L35 eIF3g PF12353.3 CBZ50556.1 - 0.051 13.4 1.9 0.062 13.2 1.3 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit G CheR_N PF03705.10 CBZ50556.1 - 0.071 12.4 0.6 0.17 11.2 0.4 1.6 1 0 0 1 1 1 0 CheR methyltransferase, all-alpha domain TSP_1 PF00090.14 CBZ50558.1 - 1.5e-06 28.2 13.1 0.0065 16.5 0.8 3.0 2 0 0 2 2 2 2 Thrombospondin type 1 domain Peptidase_S8 PF00082.17 CBZ50559.1 - 4.5e-13 48.9 8.6 3.8e-09 36.0 0.3 2.2 1 1 1 2 2 2 2 Subtilase family Fcf1 PF04900.7 CBZ50560.1 - 1.4e-37 127.8 1.4 1.4e-37 127.8 1.0 1.8 2 0 0 2 2 2 1 Fcf1 Daxx PF03344.10 CBZ50560.1 - 8.1 4.7 44.1 0.086 11.3 25.1 1.7 2 0 0 2 2 2 0 Daxx Family Ycf1 PF05758.7 CBZ50560.1 - 8.3 3.9 22.1 0.22 9.2 10.3 1.8 2 0 0 2 2 2 0 Ycf1 V-SNARE_C PF12352.3 CBZ50561.1 - 9.7e-09 35.1 12.6 5.1e-06 26.4 0.3 2.6 3 0 0 3 3 3 2 Snare region anchored in the vesicle membrane C-terminus SNARE PF05739.14 CBZ50561.1 - 9.1e-08 31.6 11.8 1.1e-06 28.1 3.6 2.5 2 0 0 2 2 2 2 SNARE domain NPV_P10 PF05531.7 CBZ50561.1 - 0.0071 16.5 6.5 0.041 14.1 0.4 2.3 2 0 0 2 2 2 1 Nucleopolyhedrovirus P10 protein Sec20 PF03908.8 CBZ50561.1 - 0.065 12.9 0.2 0.065 12.9 0.2 2.1 2 0 0 2 2 2 0 Sec20 Flagellin_N PF00669.15 CBZ50561.1 - 0.21 11.3 5.0 0.64 9.8 0.0 2.5 2 0 0 2 2 2 0 Bacterial flagellin N-terminal helical region DUF948 PF06103.6 CBZ50561.1 - 0.22 11.4 4.9 1.9 8.4 0.4 2.3 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) DASH_Duo1 PF08651.5 CBZ50561.1 - 2.3 7.8 6.9 13 5.4 0.9 2.3 2 0 0 2 2 2 0 DASH complex subunit Duo1 SlyX PF04102.7 CBZ50561.1 - 9.8 6.6 10.5 3.3 8.1 2.6 2.8 2 0 0 2 2 2 0 SlyX SAPS PF04499.10 CBZ50562.1 - 5.2e-10 38.5 5.4 3.2e-08 32.6 0.0 3.6 3 2 0 3 3 3 2 SIT4 phosphatase-associated protein 2-oxoacid_dh PF00198.18 CBZ50563.1 - 3e-68 229.5 0.3 4.2e-68 229.0 0.2 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 CBZ50563.1 - 1.1e-19 69.8 1.1 2.1e-19 68.9 0.7 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.12 CBZ50563.1 - 2.7e-16 58.9 0.3 1.6e-15 56.4 0.0 2.5 3 0 0 3 3 3 1 e3 binding domain Biotin_lipoyl_2 PF13533.1 CBZ50563.1 - 0.0005 19.6 0.0 0.0014 18.2 0.0 1.8 1 1 0 1 1 1 1 Biotin-lipoyl like GCV_H PF01597.14 CBZ50563.1 - 0.0024 17.5 0.1 0.0053 16.4 0.0 1.5 1 0 0 1 1 1 1 Glycine cleavage H-protein HlyD PF00529.15 CBZ50563.1 - 0.011 15.0 0.0 0.027 13.7 0.0 1.6 1 0 0 1 1 1 0 HlyD family secretion protein HlyD_2 PF12700.2 CBZ50563.1 - 0.06 12.4 0.0 0.17 11.0 0.0 1.7 2 0 0 2 2 2 0 HlyD family secretion protein DUF1510 PF07423.6 CBZ50566.1 - 0.2 11.0 10.6 0.29 10.4 7.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) MORN PF02493.15 CBZ50567.1 - 1.4e-37 125.1 41.7 9.3e-05 21.9 0.0 12.1 11 0 0 11 11 11 9 MORN repeat Avl9 PF09794.4 CBZ50567.1 - 5.4e-17 61.3 0.0 5.5e-09 34.9 0.0 2.9 3 0 0 3 3 3 2 Transport protein Avl9 UQ_con PF00179.21 CBZ50568.1 - 2.3e-53 179.3 0.0 2.6e-53 179.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 CBZ50568.1 - 2.5e-06 27.3 0.0 2.9e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 CBZ50568.1 - 0.00083 19.2 0.0 0.00099 18.9 0.0 1.3 1 0 0 1 1 1 1 RWD domain UEV PF05743.8 CBZ50568.1 - 0.013 15.1 0.0 0.02 14.5 0.0 1.3 1 0 0 1 1 1 0 UEV domain DNA_pol_B_exo1 PF03104.14 CBZ50569.1 - 2.5e-42 144.9 0.0 5e-42 143.9 0.0 1.6 1 1 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.16 CBZ50569.1 - 3.5e-17 62.3 5.0 1.2e-16 60.5 3.4 1.8 1 1 0 1 1 1 1 DNA polymerase family B DUF1744 PF08490.7 CBZ50569.1 - 1.1e-11 43.9 0.0 4.5e-10 38.6 0.0 2.8 3 0 0 3 3 3 1 Domain of unknown function (DUF1744) DNA_pol_B_exo2 PF10108.4 CBZ50569.1 - 0.0014 18.1 0.1 0.0043 16.6 0.0 1.8 2 0 0 2 2 2 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.1 CBZ50569.1 - 0.002 17.9 0.0 0.0064 16.3 0.0 1.9 1 0 0 1 1 1 1 RNase_H superfamily RRM_5 PF13893.1 CBZ50570.1 - 4.8e-09 35.9 0.0 5.8e-05 22.8 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CBZ50570.1 - 4.8e-06 26.1 0.0 0.01 15.4 0.0 2.8 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBZ50570.1 - 0.00021 21.2 0.0 0.058 13.3 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF791 PF05631.9 CBZ50571.1 - 1.4e-59 201.6 1.8 2.4e-43 148.2 0.9 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF791) MFS_1 PF07690.11 CBZ50571.1 - 3.9e-16 58.7 14.1 3.9e-16 58.7 9.8 3.0 2 1 0 2 2 2 1 Major Facilitator Superfamily DUF842 PF05811.8 CBZ50572.1 - 1.5e-18 66.5 9.6 1.7e-18 66.3 6.7 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF842) DUF1220 PF06758.8 CBZ50572.1 - 0.09 12.5 0.3 0.28 11.0 0.0 2.0 2 0 0 2 2 2 0 Repeat of unknown function (DUF1220) UBA_e1_C PF09358.5 CBZ50572.1 - 0.1 12.7 0.0 1.5 9.0 0.0 2.0 2 0 0 2 2 2 0 Ubiquitin-activating enzyme e1 C-terminal domain GAS PF13851.1 CBZ50572.1 - 0.12 11.5 0.0 6.7 5.8 0.0 2.1 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding zf-Tim10_DDP PF02953.10 CBZ50572.1 - 4.2 6.7 15.3 0.022 14.0 1.7 3.0 1 1 2 3 3 3 0 Tim10/DDP family zinc finger DUF2036 PF09724.4 CBZ50573.1 - 1.1e-06 28.1 0.0 0.0028 16.8 0.0 2.2 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2036) Kinesin PF00225.18 CBZ50574.1 - 4.3e-83 278.7 0.0 2.5e-82 276.2 0.0 2.1 1 1 0 1 1 1 1 Kinesin motor domain MSA-2c PF12238.3 CBZ50574.1 - 0.044 13.4 1.3 0.17 11.5 0.9 2.0 1 0 0 1 1 1 0 Merozoite surface antigen 2c Surfac_D-trimer PF09006.6 CBZ50574.1 - 0.36 10.5 6.2 0.13 12.0 0.4 3.1 3 0 0 3 3 3 0 Lung surfactant protein D coiled-coil trimerisation SlyX PF04102.7 CBZ50574.1 - 0.56 10.6 11.7 0.32 11.3 0.4 4.4 4 0 0 4 4 4 0 SlyX Pkinase PF00069.20 CBZ50575.1 - 4.4e-59 199.7 0.0 5.2e-59 199.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ50575.1 - 1.3e-34 119.4 0.0 1.5e-34 119.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBZ50575.1 - 3.1e-06 26.3 0.0 3.6e-05 22.8 0.0 2.0 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 CBZ50575.1 - 0.0001 22.1 0.1 0.073 12.7 0.2 2.4 2 1 1 3 3 3 2 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 CBZ50575.1 - 0.036 12.8 0.1 0.045 12.5 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase FKBP_C PF00254.23 CBZ50576.1 - 0.058 13.4 0.0 0.099 12.6 0.0 1.3 1 0 0 1 1 1 0 FKBP-type peptidyl-prolyl cis-trans isomerase Laminin_G_2 PF02210.19 CBZ50577.1 - 0.0016 18.4 0.0 0.0025 17.8 0.0 1.3 1 0 0 1 1 1 1 Laminin G domain MMtag PF10159.4 CBZ50579.1 - 2.5e-17 62.6 1.1 2.5e-17 62.6 0.8 2.3 2 0 0 2 2 2 1 Kinase phosphorylation protein CxxCxxCC PF03692.10 CBZ50579.1 - 0.023 15.1 0.6 0.043 14.2 0.4 1.4 1 0 0 1 1 1 0 Putative zinc- or iron-chelating domain Rubis-subs-bind PF09273.6 CBZ50580.1 - 3.2e-11 43.2 0.0 7.3e-11 42.0 0.0 1.6 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding SET PF00856.23 CBZ50580.1 - 1.9e-05 25.0 0.0 6.2e-05 23.3 0.0 1.9 1 1 0 1 1 1 1 SET domain CBF PF03914.12 CBZ50581.1 - 4.5e-22 78.2 0.0 1.7e-21 76.3 0.0 2.1 1 1 0 1 1 1 1 CBF/Mak21 family RNase_PH PF01138.16 CBZ50582.1 - 6.3e-28 97.7 0.2 8.8e-28 97.2 0.1 1.2 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 Bestrophin PF01062.16 CBZ50585.1 - 3e-20 72.3 2.7 3.9e-20 71.9 1.8 1.1 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel Pkinase PF00069.20 CBZ50586.1 - 7.7e-27 94.0 0.0 2e-26 92.7 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ50586.1 - 7.9e-14 51.3 0.1 1.2e-12 47.4 0.0 2.4 3 0 0 3 3 3 1 Protein tyrosine kinase RWD PF05773.17 CBZ50586.1 - 0.0002 21.2 0.0 0.00044 20.1 0.0 1.5 1 0 0 1 1 1 1 RWD domain Mec-17 PF05301.6 CBZ50587.1 - 2.8e-31 107.9 0.1 4.6e-31 107.2 0.0 1.3 1 0 0 1 1 1 1 Touch receptor neuron protein Mec-17 Acetyltransf_10 PF13673.1 CBZ50587.1 - 0.086 12.9 0.0 0.21 11.7 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain AAA_12 PF13087.1 CBZ50588.1 - 1.2e-31 109.7 0.0 5e-22 78.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_11 PF13086.1 CBZ50588.1 - 3.7e-15 56.1 0.0 3.7e-15 56.1 0.0 3.3 3 1 1 4 4 4 1 AAA domain DUF2439 PF10382.4 CBZ50588.1 - 4.5e-07 29.9 0.3 1.8e-06 28.0 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2439) Viral_helicase1 PF01443.13 CBZ50588.1 - 0.00077 19.0 0.0 1.5 8.2 0.0 3.2 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.1 CBZ50588.1 - 0.0057 16.3 0.0 0.021 14.5 0.0 2.0 1 0 0 1 1 1 1 Part of AAA domain Peptidase_U57 PF05582.7 CBZ50588.1 - 3.1 6.7 0.9 7.2 5.4 0.6 1.5 1 0 0 1 1 1 0 YabG peptidase U57 WD40 PF00400.27 CBZ50590.1 - 2.6e-54 179.2 10.7 6.7e-09 35.2 0.1 7.6 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 CBZ50590.1 - 4.9e-07 28.2 1.1 0.048 11.8 0.0 3.4 2 1 0 2 2 2 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 CBZ50590.1 - 0.012 14.3 0.1 2.3 6.8 0.0 3.1 2 2 1 3 3 3 0 Nup133 N terminal like EGF_3 PF12947.2 CBZ50591.1 - 2.7e-08 33.6 9.9 2.7e-08 33.6 6.9 5.9 5 1 0 5 5 5 3 EGF domain EGF_CA PF07645.10 CBZ50591.1 - 0.00053 19.9 8.5 0.00053 19.9 5.9 6.8 5 2 1 6 6 6 2 Calcium-binding EGF domain cEGF PF12662.2 CBZ50591.1 - 0.00074 19.1 2.1 0.00074 19.1 1.5 6.6 6 1 0 6 6 6 4 Complement Clr-like EGF-like EGF PF00008.22 CBZ50591.1 - 0.0045 16.9 4.3 0.0045 16.9 3.0 7.8 6 1 2 8 8 8 4 EGF-like domain UPF0016 PF01169.14 CBZ50592.1 - 5.7e-40 135.3 26.1 3.7e-23 81.4 4.8 2.7 3 0 0 3 3 3 2 Uncharacterized protein family UPF0016 DUF3592 PF12158.3 CBZ50592.1 - 0.025 14.3 0.0 0.13 12.0 0.0 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3592) EF-hand_1 PF00036.27 CBZ50593.1 - 6.8e-06 25.0 0.2 0.24 10.7 0.0 3.5 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.1 CBZ50593.1 - 3.8e-05 23.7 0.8 0.0013 18.8 0.3 2.6 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.1 CBZ50593.1 - 0.00018 21.0 0.3 0.76 9.8 0.1 3.2 3 0 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.1 CBZ50593.1 - 0.15 11.7 1.1 0.85 9.2 0.1 2.3 1 1 1 2 2 2 0 EF-hand domain pair RRM_1 PF00076.17 CBZ50594.1 - 3.7e-27 93.7 0.0 1.1e-16 60.2 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBZ50594.1 - 1.6e-19 69.6 0.0 8e-12 44.9 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBZ50594.1 - 6.5e-09 35.5 0.0 0.00012 21.8 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 CBZ50594.1 - 0.18 11.6 0.0 0.38 10.5 0.0 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Blt1 PF12754.2 CBZ50596.1 - 0.011 15.3 0.1 0.02 14.4 0.0 1.4 1 0 0 1 1 1 0 Cell-cycle control medial ring component dCMP_cyt_deam_1 PF00383.17 CBZ50596.1 - 0.085 12.5 0.1 0.15 11.6 0.1 1.5 1 1 0 1 1 1 0 Cytidine and deoxycytidylate deaminase zinc-binding region Myco_19_kDa PF05481.7 CBZ50596.1 - 5.6 6.7 7.2 7.5 6.3 0.2 2.3 2 0 0 2 2 2 0 Mycobacterium 19 kDa lipoprotein antigen CECR6_TMEM121 PF14997.1 CBZ50597.1 - 3.8e-15 56.0 1.8 3.8e-15 56.0 1.2 2.2 2 0 0 2 2 2 1 CECR6/TMEM121 family Mem_trans PF03547.13 CBZ50600.1 - 0.16 10.2 0.2 0.21 9.8 0.1 1.3 1 0 0 1 1 1 0 Membrane transport protein SAG PF04092.8 CBZ50602.1 - 7.8e-10 39.2 3.1 0.00014 22.2 0.0 2.7 3 0 0 3 3 3 2 SRS domain DUF2957 PF11170.3 CBZ50603.1 - 0.029 13.0 2.6 0.031 12.9 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2957) SAG PF04092.8 CBZ50604.1 - 4.3e-06 27.1 4.5 0.037 14.4 0.1 2.8 3 0 0 3 3 3 2 SRS domain YqgB PF11036.3 CBZ50605.1 - 0.58 9.7 0.0 0.58 9.7 0.0 2.6 3 0 0 3 3 3 0 Virulence promoting factor Kelch_3 PF13415.1 CBZ50606.1 - 3.1e-32 109.9 9.9 1.9e-06 27.8 0.0 6.3 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_5 PF13854.1 CBZ50606.1 - 7.2e-30 102.4 7.4 4.2e-07 29.7 0.0 5.6 5 1 0 5 5 5 5 Kelch motif Kelch_4 PF13418.1 CBZ50606.1 - 2.4e-29 100.8 11.4 1.8e-09 37.1 0.0 6.0 5 1 1 6 6 6 4 Galactose oxidase, central domain Kelch_2 PF07646.10 CBZ50606.1 - 1.7e-25 87.7 5.1 2.2e-05 24.0 0.0 5.6 5 1 0 5 5 5 5 Kelch motif Kelch_6 PF13964.1 CBZ50606.1 - 3.3e-21 74.4 5.5 2.5e-06 27.4 0.0 5.6 3 1 2 5 5 5 4 Kelch motif Kelch_1 PF01344.20 CBZ50606.1 - 4.1e-19 67.8 3.9 0.00021 20.7 0.0 5.8 5 1 0 5 5 5 5 Kelch motif RAG2 PF03089.9 CBZ50606.1 - 0.0067 15.1 5.6 9.7 4.8 0.1 4.7 4 1 1 5 5 5 1 Recombination activating protein 2 RDD PF06271.7 CBZ50607.1 - 0.23 11.3 0.4 0.41 10.5 0.3 1.3 1 0 0 1 1 1 0 RDD family Gaa1 PF04114.9 CBZ50609.1 - 1.1e-13 50.7 1.4 3.2e-12 45.9 0.1 2.7 2 1 0 2 2 2 1 Gaa1-like, GPI transamidase component DUF1510 PF07423.6 CBZ50609.1 - 0.0051 16.2 2.6 0.025 13.9 0.2 2.5 3 0 0 3 3 3 1 Protein of unknown function (DUF1510) DUF812 PF05667.6 CBZ50610.1 - 0.56 8.6 13.7 1 7.7 9.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Pkinase PF00069.20 CBZ50611.1 - 6.7e-36 123.7 0.0 4.5e-27 94.8 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ50611.1 - 3.4e-22 78.7 0.0 3.8e-17 62.2 0.0 2.2 1 1 1 2 2 2 2 Protein tyrosine kinase Macoilin PF09726.4 CBZ50612.1 - 4.1e-05 22.0 27.5 0.00012 20.5 12.3 2.1 1 1 1 2 2 2 2 Transmembrane protein SF-assemblin PF06705.6 CBZ50612.1 - 7.1e-05 22.0 32.2 0.0015 17.7 17.2 3.4 1 1 1 2 2 2 1 SF-assemblin/beta giardin IL31 PF15209.1 CBZ50612.1 - 0.0053 16.3 0.1 0.011 15.3 0.0 1.5 1 0 0 1 1 1 1 Interleukin 31 FlaC_arch PF05377.6 CBZ50612.1 - 0.035 14.0 5.7 0.36 10.7 0.0 3.6 3 1 0 3 3 3 0 Flagella accessory protein C (FlaC) Baculo_PEP_C PF04513.7 CBZ50612.1 - 1.4 8.6 9.0 12 5.7 0.8 3.1 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF3584 PF12128.3 CBZ50612.1 - 2.1 5.5 33.1 0.069 10.4 12.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) MitMem_reg PF13012.1 CBZ50612.1 - 2.4 8.2 10.8 9.2 6.3 0.7 3.4 2 1 1 3 3 3 0 Maintenance of mitochondrial structure and function FlgN PF05130.7 CBZ50612.1 - 4 7.6 35.9 2.8 8.2 15.0 3.0 1 1 2 3 3 3 0 FlgN protein DeoC PF01791.4 CBZ50613.1 - 1.5e-13 50.6 1.5 2.1e-13 50.1 1.1 1.2 1 0 0 1 1 1 1 DeoC/LacD family aldolase Glycos_transf_2 PF00535.21 CBZ50615.1 - 2.4e-22 79.3 0.0 4.2e-22 78.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.17 CBZ50615.1 - 5.4e-16 58.7 0.4 8.6e-16 58.0 0.3 1.3 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glyco_tranf_2_2 PF10111.4 CBZ50615.1 - 6.2e-08 32.0 0.0 1.1e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_7C PF02709.9 CBZ50615.1 - 1.5e-07 30.8 0.0 3.1e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_3 PF13641.1 CBZ50615.1 - 8.6e-05 22.4 0.0 0.00014 21.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Peptidase_S29 PF02907.10 CBZ50615.1 - 0.14 11.6 0.0 0.24 10.9 0.0 1.3 1 0 0 1 1 1 0 Hepatitis C virus NS3 protease GlcNAc PF11397.3 CBZ50615.1 - 0.3 10.1 0.7 1.1 8.2 0.5 1.8 1 1 0 1 1 1 0 Glycosyltransferase (GlcNAc) Ala_racemase_N PF01168.15 CBZ50616.1 - 6.1e-35 120.7 3.6 3.8e-24 85.4 1.2 3.0 2 1 0 2 2 2 2 Alanine racemase, N-terminal domain ABC_tran PF00005.22 CBZ50617.1 - 9.4e-41 139.3 0.2 3.4e-22 79.2 0.0 3.1 3 0 0 3 3 2 2 ABC transporter ABC_tran_2 PF12848.2 CBZ50617.1 - 1.2e-18 66.7 6.2 2.2e-17 62.6 0.0 3.5 3 0 0 3 3 3 1 ABC transporter AAA_21 PF13304.1 CBZ50617.1 - 1.4e-17 64.5 3.9 1.5e-06 28.4 0.1 4.2 3 1 0 4 4 4 3 AAA domain SMC_N PF02463.14 CBZ50617.1 - 3.2e-07 29.8 2.2 0.0095 15.1 0.0 4.0 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_15 PF13175.1 CBZ50617.1 - 1.4e-05 24.3 1.2 1.8 7.5 0.0 4.1 4 0 0 4 4 4 2 AAA ATPase domain AAA_29 PF13555.1 CBZ50617.1 - 3.8e-05 23.1 0.1 0.02 14.4 0.0 2.9 2 0 0 2 2 2 1 P-loop containing region of AAA domain Miro PF08477.8 CBZ50617.1 - 6.2e-05 23.4 0.0 0.067 13.6 0.0 2.7 2 0 0 2 2 2 1 Miro-like protein AAA_17 PF13207.1 CBZ50617.1 - 0.00024 21.9 1.3 0.077 13.8 0.3 3.1 2 1 0 2 2 2 1 AAA domain DUF258 PF03193.11 CBZ50617.1 - 0.00046 19.4 0.1 0.2 10.8 0.1 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_18 PF13238.1 CBZ50617.1 - 0.0007 19.8 0.8 0.15 12.3 0.0 3.4 4 0 0 4 4 3 1 AAA domain Dynamin_N PF00350.18 CBZ50617.1 - 0.0047 16.7 0.1 0.51 10.1 0.0 2.7 2 0 0 2 2 2 1 Dynamin family AAA_33 PF13671.1 CBZ50617.1 - 0.0072 16.2 0.6 0.27 11.1 0.0 3.0 3 0 0 3 3 3 1 AAA domain G-alpha PF00503.15 CBZ50617.1 - 0.0075 15.0 0.0 0.013 14.2 0.0 1.3 1 0 0 1 1 1 1 G-protein alpha subunit AAA_22 PF13401.1 CBZ50617.1 - 0.0078 16.3 0.6 2.7 8.1 0.3 3.5 3 1 0 3 3 2 1 AAA domain SbcCD_C PF13558.1 CBZ50617.1 - 0.0085 15.9 1.8 0.97 9.4 0.0 3.3 3 1 0 3 3 2 1 Putative exonuclease SbcCD, C subunit MMR_HSR1 PF01926.18 CBZ50617.1 - 0.035 14.0 0.0 5.6 6.9 0.0 2.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_28 PF13521.1 CBZ50617.1 - 0.05 13.5 4.7 2 8.3 0.0 3.6 4 0 0 4 4 3 0 AAA domain AAA_14 PF13173.1 CBZ50617.1 - 0.093 12.6 0.0 7.8 6.4 0.0 3.0 3 0 0 3 3 3 0 AAA domain AAA_16 PF13191.1 CBZ50617.1 - 0.11 12.4 5.0 2.4 8.1 0.1 3.2 2 1 0 2 2 2 0 AAA ATPase domain DUF999 PF06198.6 CBZ50617.1 - 0.12 12.0 0.0 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF999) DUF2422 PF10337.4 CBZ50617.1 - 0.29 9.8 0.9 0.5 9.1 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2422) AAA_23 PF13476.1 CBZ50617.1 - 0.48 10.7 0.0 0.48 10.7 0.0 3.3 4 0 0 4 4 3 0 AAA domain eIF-6 PF01912.13 CBZ50618.1 - 4.5e-80 267.4 0.1 7e-80 266.8 0.1 1.3 1 0 0 1 1 1 1 eIF-6 family RRM_1 PF00076.17 CBZ50619.1 - 7.9e-65 214.4 1.3 1.8e-16 59.4 0.0 6.9 7 0 0 7 7 7 6 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBZ50619.1 - 5.4e-54 180.0 0.4 2.5e-17 62.6 0.0 6.1 5 1 0 5 5 5 5 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBZ50619.1 - 1.6e-40 136.7 0.1 3.8e-13 49.0 0.0 5.6 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 CBZ50619.1 - 0.002 17.8 0.0 3 7.6 0.0 2.9 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif PDEase_I PF00233.14 CBZ50620.1 - 3.1e-35 122.0 0.7 2.7e-20 73.1 0.0 2.5 1 1 1 2 2 2 2 3'5'-cyclic nucleotide phosphodiesterase HD PF01966.17 CBZ50620.1 - 0.0044 17.0 0.2 0.02 14.8 0.0 2.1 2 0 0 2 2 2 1 HD domain DUF1192 PF06698.6 CBZ50620.1 - 0.16 11.7 1.2 0.55 10.0 0.9 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) PP2C PF00481.16 CBZ50621.1 - 1.2e-47 162.4 0.0 2.2e-47 161.6 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 CBZ50621.1 - 1.8e-08 34.2 0.1 0.00099 18.8 0.0 2.3 2 0 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.1 CBZ50621.1 - 4.1e-08 32.8 0.0 2.4e-07 30.3 0.0 2.1 1 1 0 1 1 1 1 Protein phosphatase 2C PNTB PF02233.11 CBZ50622.1 - 3.4e-50 171.1 0.5 5.1e-50 170.6 0.4 1.3 1 0 0 1 1 1 1 NAD(P) transhydrogenase beta subunit AlaDh_PNT_C PF01262.16 CBZ50622.1 - 4.9e-37 127.0 2.9 5.6e-37 126.8 0.7 1.9 2 1 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.14 CBZ50622.1 - 6.8e-07 28.6 0.0 0.0039 16.3 0.0 2.3 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox_2 PF07992.9 CBZ50622.1 - 0.029 14.2 0.1 0.049 13.5 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 CBZ50622.1 - 0.048 13.7 0.3 15 5.6 0.0 3.0 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase AAA_11 PF13086.1 CBZ50624.1 - 7.3e-84 281.0 0.0 3.4e-83 278.8 0.0 2.1 2 1 0 2 2 2 1 AAA domain AAA_12 PF13087.1 CBZ50624.1 - 3.1e-62 209.5 0.0 5.3e-62 208.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 CBZ50624.1 - 2.6e-11 43.1 2.5 5e-07 29.3 0.1 3.6 4 0 0 4 4 3 2 Part of AAA domain AAA_30 PF13604.1 CBZ50624.1 - 4.8e-07 29.5 1.1 0.00095 18.7 0.1 3.1 3 0 0 3 3 3 2 AAA domain Viral_helicase1 PF01443.13 CBZ50624.1 - 2.7e-05 23.8 1.0 0.041 13.3 0.0 3.5 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase AAA_29 PF13555.1 CBZ50624.1 - 0.0013 18.1 0.0 0.0027 17.1 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain T2SE PF00437.15 CBZ50624.1 - 0.003 16.4 0.1 0.0057 15.5 0.1 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein UvrD-helicase PF00580.16 CBZ50624.1 - 0.0055 16.0 0.0 0.24 10.6 0.0 2.4 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain AAA PF00004.24 CBZ50624.1 - 0.0078 16.4 0.3 0.023 14.8 0.2 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 CBZ50624.1 - 0.017 15.2 0.0 0.12 12.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain DEAD PF00270.24 CBZ50624.1 - 0.024 14.1 0.0 0.073 12.5 0.0 1.7 2 0 0 2 2 2 0 DEAD/DEAH box helicase AAA_23 PF13476.1 CBZ50624.1 - 0.064 13.5 0.3 0.16 12.3 0.0 1.8 2 0 0 2 2 1 0 AAA domain AAA_24 PF13479.1 CBZ50624.1 - 0.1 12.1 0.1 1.1 8.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.1 CBZ50624.1 - 0.14 11.5 0.0 0.14 11.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.10 CBZ50624.1 - 0.24 11.1 0.5 0.78 9.4 0.1 2.0 2 0 0 2 2 2 0 NTPase DUF2075 PF09848.4 CBZ50624.1 - 0.48 9.3 2.1 0.67 8.8 0.1 2.3 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2075) AP2 PF00847.15 CBZ50625.1 - 4.9e-07 29.7 2.6 9.5e-07 28.8 1.8 1.5 1 0 0 1 1 1 1 AP2 domain DUF1522 PF07482.6 CBZ50625.1 - 0.028 14.5 0.1 0.3 11.2 0.0 2.5 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1522) ACDC PF14733.1 CBZ50625.1 - 0.078 13.1 0.0 0.16 12.1 0.0 1.4 1 0 0 1 1 1 0 AP2-coincident C-terminal DFP PF04127.10 CBZ50626.1 - 2.8e-07 30.3 0.0 1.7e-06 27.8 0.0 1.8 1 1 0 2 2 2 1 DNA / pantothenate metabolism flavoprotein DUF3886 PF13025.1 CBZ50626.1 - 3.1 7.8 6.2 2.1 8.4 0.2 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3886) ParA PF10609.4 CBZ50627.1 - 2.5e-31 107.3 0.3 5e-31 106.4 0.2 1.5 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 CBZ50627.1 - 7.7e-19 67.8 0.0 1.2e-18 67.2 0.0 1.3 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain DUF59 PF01883.14 CBZ50627.1 - 2e-16 59.7 0.0 4.8e-16 58.4 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function DUF59 AAA_31 PF13614.1 CBZ50627.1 - 1.3e-09 38.1 0.0 9.8e-09 35.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain MipZ PF09140.6 CBZ50627.1 - 4e-05 22.8 0.2 0.00017 20.7 0.0 1.9 2 0 0 2 2 2 1 ATPase MipZ ArsA_ATPase PF02374.10 CBZ50627.1 - 8e-05 21.8 0.6 0.082 11.9 0.2 2.4 2 0 0 2 2 2 2 Anion-transporting ATPase DUF971 PF06155.7 CBZ50627.1 - 0.00012 22.3 0.0 0.00032 21.0 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF971) YhjQ PF06564.7 CBZ50627.1 - 0.016 14.6 0.0 0.077 12.3 0.1 1.9 2 0 0 2 2 2 0 YhjQ protein Fer4_NifH PF00142.13 CBZ50627.1 - 0.12 11.5 0.0 0.19 10.8 0.0 1.3 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family VirC1 PF07015.6 CBZ50627.1 - 0.14 11.2 0.1 0.23 10.4 0.1 1.3 1 0 0 1 1 1 0 VirC1 protein PGM_PMM_I PF02878.11 CBZ50628.1 - 2.4e-38 130.7 0.1 4.7e-38 129.7 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.11 CBZ50628.1 - 4.3e-22 78.4 0.1 2e-21 76.2 0.1 2.1 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.11 CBZ50628.1 - 8.2e-09 35.5 0.0 3.9e-07 30.1 0.0 2.3 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.15 CBZ50628.1 - 4.4e-07 29.8 0.0 1.3e-06 28.2 0.0 1.8 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain Got1 PF04178.7 CBZ50629.1 - 1.2e-30 106.0 19.2 2e-30 105.2 13.3 1.3 1 0 0 1 1 1 1 Got1/Sft2-like family DUF986 PF06173.7 CBZ50629.1 - 2.1 8.1 7.7 0.95 9.2 1.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF986) BCDHK_Adom3 PF10436.4 CBZ50630.1 - 6.8e-31 106.9 0.1 1.1e-30 106.3 0.1 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 CBZ50630.1 - 2.3e-18 65.9 0.0 5.2e-18 64.7 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 CBZ50630.1 - 0.001 18.7 0.0 0.0018 17.9 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.1 CBZ50630.1 - 0.087 12.6 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain EGF_CA PF07645.10 CBZ50632.1 - 4.9e-30 103.2 60.5 6.7e-11 41.9 3.5 6.5 6 0 0 6 6 6 5 Calcium-binding EGF domain cEGF PF12662.2 CBZ50632.1 - 4.2e-21 74.2 43.5 5e-09 35.6 0.2 7.3 7 1 0 7 7 7 4 Complement Clr-like EGF-like FXa_inhibition PF14670.1 CBZ50632.1 - 3.6e-16 58.9 49.7 5.2e-08 32.8 3.8 6.2 6 0 0 6 6 6 5 Coagulation Factor Xa inhibitory site EGF_3 PF12947.2 CBZ50632.1 - 2e-09 37.2 46.5 5.5e-05 23.0 0.1 5.9 5 0 0 5 5 5 4 EGF domain EGF PF00008.22 CBZ50632.1 - 5.1e-08 32.7 52.4 0.01 15.7 1.9 6.2 6 0 0 6 6 6 5 EGF-like domain EF-hand_7 PF13499.1 CBZ50633.1 - 0.0081 16.2 0.0 0.19 11.9 0.0 2.6 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.1 CBZ50633.1 - 0.051 13.4 0.0 0.84 9.6 0.0 2.8 3 0 0 3 3 3 0 EF-hand domain His_Phos_1 PF00300.17 CBZ50633.1 - 0.11 12.5 0.0 0.22 11.6 0.0 1.5 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 1) EF-hand_9 PF14658.1 CBZ50633.1 - 0.12 12.3 0.0 1.3 8.9 0.0 2.7 4 0 0 4 4 4 0 EF-hand domain PolC_DP2 PF03833.8 CBZ50635.1 - 0.39 8.3 0.0 0.56 7.8 0.0 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 AAA PF00004.24 CBZ50636.1 - 2.4e-58 196.0 0.0 9.2e-41 139.1 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 CBZ50636.1 - 3.6e-12 46.5 3.6 0.0012 19.0 0.5 4.7 3 2 1 4 4 3 2 AAA domain AAA_16 PF13191.1 CBZ50636.1 - 1.1e-11 45.0 0.0 7.6e-05 22.7 0.0 2.8 2 1 0 2 2 2 2 AAA ATPase domain AAA_33 PF13671.1 CBZ50636.1 - 9e-10 38.5 0.0 0.0018 18.1 0.0 2.8 3 0 0 3 3 2 2 AAA domain AAA_14 PF13173.1 CBZ50636.1 - 2.1e-09 37.3 0.0 0.00097 19.0 0.0 2.9 3 0 0 3 3 3 2 AAA domain AAA_17 PF13207.1 CBZ50636.1 - 5.1e-09 36.9 0.0 0.0016 19.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.1 CBZ50636.1 - 6.3e-09 35.4 0.0 0.0061 16.2 0.0 2.8 2 0 0 2 2 2 2 Part of AAA domain AAA_5 PF07728.9 CBZ50636.1 - 1e-08 35.0 0.1 0.0026 17.4 0.0 2.9 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) TIP49 PF06068.8 CBZ50636.1 - 2.8e-08 32.9 0.0 0.0061 15.3 0.0 2.2 2 0 0 2 2 2 2 TIP49 C-terminus RuvB_N PF05496.7 CBZ50636.1 - 6.2e-08 31.9 0.1 0.0022 17.1 0.0 2.7 2 1 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_2 PF07724.9 CBZ50636.1 - 1.3e-07 31.7 0.0 4.4e-05 23.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_18 PF13238.1 CBZ50636.1 - 4e-07 30.3 0.0 0.029 14.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.12 CBZ50636.1 - 4.6e-07 29.4 0.0 0.031 13.6 0.0 2.8 3 0 0 3 3 2 2 IstB-like ATP binding protein Zeta_toxin PF06414.7 CBZ50636.1 - 1.2e-06 27.8 0.0 0.051 12.6 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin CDC48_N PF02359.13 CBZ50636.1 - 1.4e-06 28.1 0.0 5.4e-06 26.2 0.0 2.1 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain RNA_helicase PF00910.17 CBZ50636.1 - 1.5e-06 28.2 0.0 0.066 13.3 0.0 2.6 2 0 0 2 2 2 2 RNA helicase AAA_25 PF13481.1 CBZ50636.1 - 2.2e-06 27.2 1.2 0.13 11.6 0.0 4.1 2 2 2 4 4 4 2 AAA domain Mg_chelatase PF01078.16 CBZ50636.1 - 2.4e-06 26.8 0.2 0.024 13.8 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI NACHT PF05729.7 CBZ50636.1 - 3.4e-06 26.8 0.0 0.013 15.1 0.0 3.2 3 0 0 3 3 3 2 NACHT domain NB-ARC PF00931.17 CBZ50636.1 - 3.6e-06 26.0 0.0 0.015 14.1 0.0 2.5 2 0 0 2 2 2 2 NB-ARC domain AAA_28 PF13521.1 CBZ50636.1 - 9.4e-06 25.6 0.0 0.088 12.7 0.0 2.9 3 0 0 3 3 3 2 AAA domain KaiC PF06745.8 CBZ50636.1 - 9.8e-06 24.8 0.0 0.0026 16.8 0.0 2.4 2 0 0 2 2 2 1 KaiC Arch_ATPase PF01637.13 CBZ50636.1 - 1.2e-05 25.0 0.3 0.32 10.6 0.0 3.6 2 1 1 3 3 3 1 Archaeal ATPase AAA_24 PF13479.1 CBZ50636.1 - 1.7e-05 24.5 0.1 0.051 13.1 0.1 2.5 2 0 0 2 2 2 2 AAA domain DUF2075 PF09848.4 CBZ50636.1 - 3e-05 23.1 0.0 0.0095 14.9 0.0 2.3 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) Sigma54_activat PF00158.21 CBZ50636.1 - 9.4e-05 21.9 0.0 0.4 10.1 0.0 2.6 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_11 PF13086.1 CBZ50636.1 - 0.00033 20.2 0.0 0.48 9.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain ABC_tran PF00005.22 CBZ50636.1 - 0.00054 20.2 0.0 0.41 10.9 0.0 2.5 2 0 0 2 2 2 1 ABC transporter AAA_3 PF07726.6 CBZ50636.1 - 0.00055 19.5 0.0 1.3 8.6 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) PhoH PF02562.11 CBZ50636.1 - 0.001 18.3 0.0 1.6 7.9 0.0 2.4 2 0 0 2 2 2 2 PhoH-like protein ResIII PF04851.10 CBZ50636.1 - 0.0011 18.8 0.0 1.6 8.4 0.0 2.5 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit UPF0079 PF02367.12 CBZ50636.1 - 0.0049 16.4 0.0 0.47 10.0 0.0 2.3 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 Parvo_NS1 PF01057.12 CBZ50636.1 - 0.0053 15.6 0.0 0.82 8.4 0.0 2.3 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 Bac_DnaA PF00308.13 CBZ50636.1 - 0.0054 16.4 0.0 0.75 9.4 0.0 2.8 3 0 0 3 3 3 1 Bacterial dnaA protein Rad17 PF03215.10 CBZ50636.1 - 0.0088 14.7 0.0 0.14 10.7 0.0 2.3 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein DAP3 PF10236.4 CBZ50636.1 - 0.0089 14.9 0.0 0.47 9.3 0.0 2.3 2 0 0 2 2 2 1 Mitochondrial ribosomal death-associated protein 3 AAA_30 PF13604.1 CBZ50636.1 - 0.0094 15.5 0.0 1.3 8.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain Sigma54_activ_2 PF14532.1 CBZ50636.1 - 0.011 15.8 0.0 5.5 7.0 0.0 2.8 3 0 0 3 3 2 0 Sigma-54 interaction domain Viral_helicase1 PF01443.13 CBZ50636.1 - 0.014 14.8 0.0 0.23 10.9 0.0 2.5 3 0 0 3 3 2 0 Viral (Superfamily 1) RNA helicase KTI12 PF08433.5 CBZ50636.1 - 0.021 14.0 0.0 1.9 7.6 0.0 2.6 3 0 0 3 3 2 0 Chromatin associated protein KTI12 ATP-synt_ab PF00006.20 CBZ50636.1 - 0.033 13.6 0.0 6.7 6.1 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain SKI PF01202.17 CBZ50636.1 - 0.035 13.9 0.8 4.4 7.1 0.0 2.9 3 1 0 3 3 2 0 Shikimate kinase NTPase_1 PF03266.10 CBZ50636.1 - 0.052 13.2 0.0 10 5.8 0.0 2.7 2 0 0 2 2 2 0 NTPase CDC48_2 PF02933.12 CBZ50636.1 - 0.06 12.9 0.1 0.76 9.4 0.0 2.5 2 0 0 2 2 2 0 Cell division protein 48 (CDC48), domain 2 cobW PF02492.14 CBZ50636.1 - 0.074 12.5 0.0 7.5 5.9 0.0 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain CPT PF07931.7 CBZ50636.1 - 0.078 12.5 0.0 0.45 10.1 0.0 2.1 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein IPT PF01745.11 CBZ50636.1 - 0.082 12.0 0.0 3.7 6.6 0.0 2.3 2 0 0 2 2 2 0 Isopentenyl transferase TrwB_AAD_bind PF10412.4 CBZ50636.1 - 0.16 10.5 0.0 2.7 6.5 0.0 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain RNA_Me_trans PF04252.8 CBZ50638.1 - 5.8e-34 117.2 0.0 6.6e-34 117.0 0.0 1.1 1 0 0 1 1 1 1 Predicted SAM-dependent RNA methyltransferase SNF2_N PF00176.18 CBZ50639.1 - 4.2e-55 186.6 0.0 8e-31 106.9 0.0 2.3 2 0 0 2 2 2 2 SNF2 family N-terminal domain UBA_4 PF14555.1 CBZ50639.1 - 4.8e-09 35.6 0.0 1.1e-08 34.5 0.0 1.6 1 0 0 1 1 1 1 UBA-like domain zf-C3HC4_3 PF13920.1 CBZ50639.1 - 2.3e-08 33.5 11.7 2.3e-08 33.5 8.1 1.8 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CBZ50639.1 - 9.2e-08 31.9 14.3 9.2e-08 31.9 9.9 2.0 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CBZ50639.1 - 2.4e-06 27.2 13.3 6.7e-06 25.8 9.2 1.9 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 CBZ50639.1 - 3.7e-06 26.5 11.1 3.7e-06 26.5 7.7 2.2 2 0 0 2 2 2 1 zinc-RING finger domain Helicase_C PF00271.26 CBZ50639.1 - 7.2e-06 25.7 0.0 2.1e-05 24.2 0.0 1.8 1 1 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4 PF00097.20 CBZ50639.1 - 8.5e-06 25.3 16.1 9e-06 25.2 9.4 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 CBZ50639.1 - 0.0063 16.3 13.5 0.015 15.1 9.4 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Haem_bd PF14376.1 CBZ50639.1 - 0.0077 15.9 0.0 0.014 15.0 0.0 1.4 1 0 0 1 1 1 1 Haem-binding domain zf-Nse PF11789.3 CBZ50639.1 - 1.1 8.7 7.0 2.7 7.5 4.8 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_6 PF14835.1 CBZ50639.1 - 1.6 8.5 7.0 4.3 7.1 4.8 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_4 PF14570.1 CBZ50639.1 - 7 6.3 13.2 0.92 9.1 5.8 2.1 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain DUF3402 PF11882.3 CBZ50640.1 - 4.4 6.2 0.1 7.3 5.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3402) Hydrolase PF00702.21 CBZ50641.1 - 3.1e-16 60.4 0.2 1.1e-07 32.4 0.0 3.5 3 1 0 3 3 3 2 haloacid dehalogenase-like hydrolase HAD PF12710.2 CBZ50641.1 - 3e-14 53.6 0.0 8.2e-14 52.2 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 CBZ50641.1 - 5.9e-09 35.2 0.1 1.2e-05 24.4 0.0 2.4 1 1 0 2 2 2 2 E1-E2 ATPase Hydrolase_like2 PF13246.1 CBZ50641.1 - 0.071 13.0 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 Putative hydrolase of sodium-potassium ATPase alpha subunit Pam17 PF08566.5 CBZ50641.1 - 0.16 11.6 0.0 0.43 10.2 0.0 1.7 1 0 0 1 1 1 0 Mitochondrial import protein Pam17 Hydrolase_3 PF08282.7 CBZ50641.1 - 0.62 9.5 0.0 1.2 8.7 0.0 1.3 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase zf-C3HC4_2 PF13923.1 CBZ50642.1 - 3e-09 36.7 14.6 3e-09 36.7 10.1 3.4 2 1 1 3 3 1 1 Zinc finger, C3HC4 type (RING finger) zf-TRAF PF02176.13 CBZ50642.1 - 1.3e-08 35.0 2.3 1.3e-08 35.0 1.6 3.5 2 1 1 3 3 3 1 TRAF-type zinc finger zf-C3HC4 PF00097.20 CBZ50642.1 - 1.6e-07 30.8 15.4 1.6e-07 30.8 10.7 3.7 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CBZ50642.1 - 5.6e-07 29.1 11.3 5.6e-07 29.1 7.8 3.2 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 CBZ50642.1 - 7.1e-07 28.9 14.4 7.1e-07 28.9 10.0 3.5 3 1 0 3 3 2 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.1 CBZ50642.1 - 5e-06 26.2 14.4 5e-06 26.2 10.0 3.2 2 1 0 2 2 1 1 Ring finger domain zf-RING_5 PF14634.1 CBZ50642.1 - 1e-05 25.1 13.8 1e-05 25.1 9.6 3.2 2 1 1 3 3 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 CBZ50642.1 - 0.0002 21.0 7.2 0.0002 21.0 5.0 2.8 2 1 1 3 3 3 1 RING-type zinc-finger zf-RAG1 PF10426.4 CBZ50642.1 - 0.012 15.4 9.2 0.061 13.2 0.0 3.3 3 0 0 3 3 3 0 Recombination-activating protein 1 zinc-finger domain U-box PF04564.10 CBZ50642.1 - 0.1 12.5 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 U-box domain Sina PF03145.11 CBZ50642.1 - 4.9 6.7 13.3 26 4.3 8.7 2.1 1 1 1 2 2 2 0 Seven in absentia protein family HA2 PF04408.18 CBZ50643.1 - 1.4e-11 44.3 0.2 3.7e-11 42.9 0.1 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 CBZ50643.1 - 1.9e-09 37.2 0.0 3.8e-09 36.2 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 CBZ50643.1 - 9.1e-07 28.5 0.0 1.9e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 CBZ50643.1 - 0.001 19.2 0.9 0.0023 18.0 0.1 2.0 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.1 CBZ50643.1 - 0.51 10.6 0.0 1 9.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain Ldh_1_N PF00056.18 CBZ50644.1 - 2.3e-39 134.4 0.0 3.9e-39 133.6 0.0 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 CBZ50644.1 - 1e-33 116.5 0.0 1.5e-33 115.9 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Glyco_hydro_4 PF02056.11 CBZ50644.1 - 4.9e-05 22.7 0.9 0.012 14.9 0.1 2.4 1 1 1 2 2 2 2 Family 4 glycosyl hydrolase F420_oxidored PF03807.12 CBZ50644.1 - 0.16 12.4 1.2 0.74 10.2 0.8 2.1 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent UDPG_MGDP_dh_N PF03721.9 CBZ50644.1 - 0.21 10.9 3.1 0.62 9.4 0.6 2.3 2 1 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Ribosomal_S16 PF00886.14 CBZ50645.1 - 1e-15 57.1 0.0 2.2e-15 56.0 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein S16 SNN_linker PF09050.5 CBZ50645.1 - 4.9 6.7 5.9 11 5.7 4.1 1.6 1 0 0 1 1 1 0 Stannin unstructured linker Cpn60_TCP1 PF00118.19 CBZ50646.1 - 2e-151 504.9 0.0 2.3e-151 504.7 0.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family PUF PF00806.14 CBZ50650.1 - 4.4e-41 136.0 0.0 9.5e-07 27.9 0.0 8.4 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat Baculo_LEF-2 PF03041.9 CBZ50650.1 - 0.98 9.0 0.0 2.1 8.0 0.0 1.4 1 0 0 1 1 1 0 lef-2 DUF605 PF04652.11 CBZ50651.1 - 1.1 8.5 23.6 1.4 8.2 16.4 1.1 1 0 0 1 1 1 0 Vta1 like CDC27 PF09507.5 CBZ50651.1 - 2.5 7.2 17.6 3.2 6.8 12.2 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 DUF2217 PF10265.4 CBZ50651.1 - 3.8 6.1 10.6 5 5.7 7.3 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) MOZ_SAS PF01853.13 CBZ50652.1 - 1e-65 220.4 0.4 1.6e-65 219.9 0.3 1.2 1 0 0 1 1 1 1 MOZ/SAS family Tudor-knot PF11717.3 CBZ50652.1 - 2.8e-10 39.7 0.0 6.1e-10 38.6 0.0 1.6 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Acetyltransf_7 PF13508.1 CBZ50652.1 - 0.083 13.0 0.0 0.18 11.9 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain CLP_protease PF00574.18 CBZ50653.1 - 9.9e-32 110.0 0.0 1.1e-23 83.8 0.0 2.1 1 1 1 2 2 2 2 Clp protease Transketolase_N PF00456.16 CBZ50654.1 - 1.8e-104 349.1 0.0 3.2e-104 348.3 0.0 1.4 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.19 CBZ50654.1 - 1.4e-32 112.6 0.0 4.8e-32 110.8 0.0 1.9 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 CBZ50654.1 - 9.8e-06 25.5 0.0 2.1e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.1 CBZ50654.1 - 9.9e-05 21.3 0.0 0.0086 15.0 0.0 2.3 1 1 1 2 2 2 2 1-deoxy-D-xylulose-5-phosphate synthase Histidinol_dh PF00815.15 CBZ50654.1 - 0.015 13.9 0.1 0.025 13.2 0.0 1.2 1 0 0 1 1 1 0 Histidinol dehydrogenase HMG_box_2 PF09011.5 CBZ50654.1 - 0.22 11.9 1.2 0.54 10.6 0.8 1.6 1 0 0 1 1 1 0 HMG-box domain PDZ_2 PF13180.1 CBZ50655.1 - 6.3e-11 42.0 0.0 9.5e-11 41.4 0.0 1.3 1 0 0 1 1 1 1 PDZ domain Trypsin_2 PF13365.1 CBZ50655.1 - 1.5e-07 31.4 0.0 3e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 Trypsin-like peptidase domain PDZ PF00595.19 CBZ50655.1 - 0.00013 22.0 0.0 0.00025 21.1 0.0 1.4 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) GRASP55_65 PF04495.9 CBZ50655.1 - 0.012 15.5 0.0 0.02 14.8 0.0 1.3 1 0 0 1 1 1 0 GRASP55/65 PDZ-like domain SRP-alpha_N PF04086.8 CBZ50656.1 - 6.6 6.0 14.2 8.1 5.7 9.8 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal FKBP_C PF00254.23 CBZ50657.1 - 7.2e-13 48.3 0.0 1.4e-12 47.4 0.0 1.4 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase FKBP_N PF01346.13 CBZ50657.1 - 1.2e-06 28.5 0.2 6.4e-06 26.2 0.0 2.1 3 0 0 3 3 3 1 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase WD40 PF00400.27 CBZ50658.1 - 6.2e-24 82.9 16.5 3.6e-05 23.4 0.2 6.5 6 0 0 6 6 6 6 WD domain, G-beta repeat TFIID_90kDa PF04494.10 CBZ50658.1 - 0.0002 21.4 0.2 0.00038 20.5 0.1 1.3 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit Nup160 PF11715.3 CBZ50658.1 - 0.078 11.0 0.1 5.7 4.9 0.0 2.6 3 0 0 3 3 3 0 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 CBZ50658.1 - 0.16 10.7 0.0 2.2 6.9 0.0 2.6 2 1 0 2 2 2 0 Nup133 N terminal like RAB3GAP2_N PF14655.1 CBZ50658.1 - 0.32 9.9 0.0 0.58 9.0 0.0 1.3 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus TTL PF03133.10 CBZ50659.1 - 1.4e-54 185.0 0.0 2.7e-53 180.7 0.0 2.7 2 1 0 2 2 2 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.1 CBZ50659.1 - 0.00011 21.1 0.0 0.00054 18.8 0.0 2.0 2 1 1 3 3 3 1 YheC/D like ATP-grasp CP_ATPgrasp_1 PF04174.8 CBZ50659.1 - 0.18 10.3 0.0 0.32 9.5 0.0 1.3 1 0 0 1 1 1 0 A circularly permuted ATPgrasp PGK PF00162.14 CBZ50660.1 - 5e-144 479.5 0.2 5.7e-144 479.4 0.1 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase DUF812 PF05667.6 CBZ50661.1 - 0.087 11.3 25.2 0.14 10.6 17.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF812) TSC22 PF01166.13 CBZ50661.1 - 8.6 6.4 8.9 16 5.5 0.2 3.4 3 0 0 3 3 3 0 TSC-22/dip/bun family His_Phos_1 PF00300.17 CBZ50663.1 - 6.9e-16 58.7 0.5 6.9e-16 58.7 0.4 2.6 2 1 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) SAG PF04092.8 CBZ50664.1 - 7.5e-41 139.3 16.5 3.1e-25 88.9 3.3 2.1 2 0 0 2 2 2 2 SRS domain DUF2859 PF11072.3 CBZ50664.1 - 0.094 12.1 0.1 0.26 10.7 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2859) Fe-S_biosyn PF01521.15 CBZ50665.1 - 0.038 13.9 0.0 0.23 11.4 0.0 2.0 2 0 0 2 2 2 0 Iron-sulphur cluster biosynthesis MC1 PF05854.6 CBZ50665.1 - 0.058 13.3 0.1 0.12 12.3 0.1 1.5 1 0 0 1 1 1 0 Non-histone chromosomal protein MC1 Motile_Sperm PF00635.21 CBZ50666.1 - 7.1e-22 77.1 0.0 1e-21 76.6 0.0 1.2 1 0 0 1 1 1 1 MSP (Major sperm protein) domain HALZ PF02183.13 CBZ50666.1 - 0.0087 15.7 2.7 0.018 14.7 1.9 1.5 1 1 0 1 1 1 1 Homeobox associated leucine zipper MFS_1 PF07690.11 CBZ50667.1 - 4.3e-13 48.7 17.1 4.3e-13 48.7 11.8 2.0 2 1 0 2 2 2 1 Major Facilitator Superfamily Folate_carrier PF01770.13 CBZ50667.1 - 0.082 11.4 7.7 0.017 13.6 2.5 1.8 3 0 0 3 3 3 0 Reduced folate carrier SART-1 PF03343.8 CBZ50668.1 - 2.5e-65 221.0 74.9 2.9e-61 207.5 51.9 4.5 1 1 0 1 1 1 1 SART-1 family SET PF00856.23 CBZ50670.1 - 8.7e-18 65.1 0.4 2.5e-16 60.4 0.0 3.6 2 1 0 2 2 2 1 SET domain AP2 PF00847.15 CBZ50671.1 - 5.3e-08 32.8 3.1 1.1e-07 31.8 2.1 1.6 1 0 0 1 1 1 1 AP2 domain Pap_E4 PF02711.9 CBZ50671.1 - 0.2 12.4 0.0 0.2 12.4 0.0 4.3 4 1 1 5 5 5 0 E4 protein TB2_DP1_HVA22 PF03134.14 CBZ50672.1 - 6e-13 48.3 4.6 9.1e-13 47.7 3.2 1.3 1 0 0 1 1 1 1 TB2/DP1, HVA22 family SAC3_GANP PF03399.11 CBZ50673.1 - 8.7e-18 64.6 0.1 1.4e-17 63.9 0.1 1.2 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family DUF3693 PF12472.3 CBZ50673.1 - 0.054 13.0 0.4 0.16 11.5 0.2 1.8 1 0 0 1 1 1 0 Phage related protein AAA_12 PF13087.1 CBZ50674.1 - 3e-54 183.4 0.0 6.3e-54 182.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 CBZ50674.1 - 4.6e-45 154.0 0.5 1.7e-44 152.1 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.1 CBZ50674.1 - 1.4e-15 56.7 0.1 1.6e-13 50.1 0.1 2.8 2 0 0 2 2 2 1 Part of AAA domain AAA_30 PF13604.1 CBZ50674.1 - 7.4e-11 41.9 0.0 7.5e-10 38.7 0.0 2.7 1 1 0 1 1 1 1 AAA domain dsrm PF00035.20 CBZ50674.1 - 7.4e-05 23.2 0.1 0.074 13.6 0.1 3.5 3 0 0 3 3 3 1 Double-stranded RNA binding motif NACHT PF05729.7 CBZ50674.1 - 0.00026 20.7 0.0 0.00061 19.4 0.0 1.6 1 0 0 1 1 1 1 NACHT domain PIF1 PF05970.9 CBZ50674.1 - 0.00061 18.8 0.0 0.0033 16.4 0.0 1.9 2 0 0 2 2 2 1 PIF1-like helicase IstB_IS21 PF01695.12 CBZ50674.1 - 0.0025 17.2 0.0 0.0057 16.0 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein DUF2075 PF09848.4 CBZ50674.1 - 0.0028 16.7 0.1 0.026 13.5 0.0 2.2 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) PhoH PF02562.11 CBZ50674.1 - 0.004 16.4 0.0 0.01 15.0 0.0 1.6 1 0 0 1 1 1 1 PhoH-like protein AAA_16 PF13191.1 CBZ50674.1 - 0.0075 16.2 0.0 0.026 14.4 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain AAA PF00004.24 CBZ50674.1 - 0.017 15.3 0.0 0.047 13.9 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ResIII PF04851.10 CBZ50674.1 - 0.045 13.5 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_25 PF13481.1 CBZ50674.1 - 0.053 12.9 0.0 0.12 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain DEAD PF00270.24 CBZ50674.1 - 0.062 12.7 0.0 0.17 11.3 0.0 1.8 1 0 0 1 1 1 0 DEAD/DEAH box helicase AAA_22 PF13401.1 CBZ50674.1 - 0.069 13.2 0.0 0.2 11.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain Thioredoxin PF00085.15 CBZ50675.1 - 8.8e-62 205.2 3.9 1e-31 108.6 0.1 3.7 4 0 0 4 4 4 3 Thioredoxin Thioredoxin_6 PF13848.1 CBZ50675.1 - 1.3e-36 126.0 4.9 1.5e-20 73.7 0.3 3.2 2 1 1 3 3 3 3 Thioredoxin-like domain Thioredoxin_2 PF13098.1 CBZ50675.1 - 4.4e-15 55.8 3.1 2.7e-06 27.5 0.1 4.6 3 2 0 3 3 3 3 Thioredoxin-like domain Thioredoxin_8 PF13905.1 CBZ50675.1 - 5.1e-12 45.7 0.1 0.00089 19.3 0.0 4.0 3 2 1 4 4 4 2 Thioredoxin-like Calsequestrin PF01216.12 CBZ50675.1 - 3.5e-10 39.2 1.2 7.9e-10 38.0 0.8 1.5 1 1 0 1 1 1 1 Calsequestrin Thioredoxin_7 PF13899.1 CBZ50675.1 - 5.8e-10 39.0 1.8 0.00041 20.3 0.0 3.2 3 0 0 3 3 3 2 Thioredoxin-like Redoxin PF08534.5 CBZ50675.1 - 1.8e-08 34.0 2.3 0.0015 18.0 0.0 2.9 3 0 0 3 3 3 2 Redoxin AhpC-TSA PF00578.16 CBZ50675.1 - 3.8e-08 33.0 0.4 0.00028 20.5 0.0 2.7 3 0 0 3 3 3 2 AhpC/TSA family Thioredoxin_9 PF14595.1 CBZ50675.1 - 1.7e-05 24.3 0.1 0.035 13.6 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin TraF PF13728.1 CBZ50675.1 - 0.0002 20.9 0.0 0.032 13.7 0.0 2.9 3 0 0 3 3 3 1 F plasmid transfer operon protein Glutaredoxin PF00462.19 CBZ50675.1 - 0.017 15.1 4.4 1.1 9.2 0.0 3.7 3 1 0 3 3 3 0 Glutaredoxin Thioredoxin_4 PF13462.1 CBZ50675.1 - 0.023 14.7 2.7 8.5 6.3 0.1 3.8 3 2 2 5 5 5 0 Thioredoxin NMD3 PF04981.8 CBZ50675.1 - 0.055 12.5 0.3 1.9 7.5 0.0 2.3 2 0 0 2 2 2 0 NMD3 family HyaE PF07449.6 CBZ50675.1 - 0.063 13.1 0.0 2.2 8.1 0.0 3.0 3 0 0 3 3 3 0 Hydrogenase-1 expression protein HyaE S1 PF00575.18 CBZ50676.1 - 5.2e-20 71.3 0.9 2.9e-11 43.2 0.1 2.4 2 0 0 2 2 2 2 S1 RNA binding domain zf-CCHC_3 PF13917.1 CBZ50676.1 - 1.6e-12 46.9 0.2 3.7e-12 45.7 0.1 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.18 CBZ50676.1 - 0.0022 17.8 5.1 0.0045 16.8 3.5 1.6 1 0 0 1 1 1 1 Zinc knuckle Nucleo_P87 PF07267.6 CBZ50676.1 - 0.0081 14.9 3.8 0.0086 14.8 2.6 1.2 1 0 0 1 1 1 1 Nucleopolyhedrovirus capsid protein P87 SR-25 PF10500.4 CBZ50676.1 - 0.037 13.5 35.2 0.072 12.5 24.4 1.5 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DnaJ_CXXCXGXG PF00684.14 CBZ50676.1 - 0.038 14.0 1.6 0.08 13.0 1.1 1.6 1 0 0 1 1 1 0 DnaJ central domain Rtf2 PF04641.7 CBZ50676.1 - 0.41 9.8 17.1 0.64 9.1 11.9 1.3 1 0 0 1 1 1 0 Rtf2 RING-finger Vfa1 PF08432.5 CBZ50676.1 - 3.8 7.4 20.2 7.3 6.5 14.0 1.4 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF501 PF04417.7 CBZ50677.1 - 1.6e-25 89.6 0.0 2.5e-14 53.3 0.0 2.4 1 1 1 2 2 2 2 Protein of unknown function (DUF501) Neuregulin PF02158.10 CBZ50677.1 - 1.1 7.9 6.7 2.2 6.9 4.6 1.5 1 0 0 1 1 1 0 Neuregulin family DUF3522 PF12036.3 CBZ50678.1 - 9.7e-10 38.5 6.4 6.3e-09 35.8 4.5 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF3522) Lge1 PF11488.3 CBZ50679.1 - 0.057 13.6 1.3 0.25 11.5 0.3 2.3 2 0 0 2 2 2 0 Transcriptional regulatory protein LGE1 DUF226 PF02890.9 CBZ50681.1 - 0.23 11.2 0.1 0.37 10.5 0.1 1.2 1 0 0 1 1 1 0 Borrelia family of unknown function DUF226 MMR_HSR1 PF01926.18 CBZ50682.1 - 2.5e-42 143.5 0.0 4.4e-21 75.0 0.0 2.3 2 0 0 2 2 2 2 50S ribosome-binding GTPase GTP_EFTU PF00009.22 CBZ50682.1 - 8.2e-20 71.0 0.0 1.3e-08 34.5 0.0 4.5 4 1 1 5 5 5 3 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 CBZ50682.1 - 1.5e-16 60.0 0.0 2.7e-09 36.4 0.0 2.3 2 0 0 2 2 2 2 Ferrous iron transport protein B KH_dom-like PF14714.1 CBZ50682.1 - 2e-12 46.9 0.6 4e-12 45.9 0.4 1.5 1 0 0 1 1 1 1 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal Miro PF08477.8 CBZ50682.1 - 1.1e-10 42.0 0.0 0.00011 22.6 0.0 3.0 3 0 0 3 3 3 2 Miro-like protein AIG1 PF04548.11 CBZ50682.1 - 2e-07 30.3 0.0 0.0057 15.7 0.0 2.8 3 0 0 3 3 3 2 AIG1 family Dynamin_N PF00350.18 CBZ50682.1 - 3.4e-07 30.2 0.0 0.24 11.2 0.0 3.9 3 1 1 4 4 4 2 Dynamin family DUF258 PF03193.11 CBZ50682.1 - 2.5e-06 26.7 0.0 0.014 14.5 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_17 PF13207.1 CBZ50682.1 - 3.3e-05 24.6 0.0 0.065 14.0 0.0 3.2 2 1 0 2 2 2 1 AAA domain ArgK PF03308.11 CBZ50682.1 - 0.00013 20.8 0.0 2.3 6.9 0.0 4.0 4 0 0 4 4 4 1 ArgK protein AAA_18 PF13238.1 CBZ50682.1 - 0.00029 21.1 0.0 0.83 9.9 0.0 2.9 2 0 0 2 2 2 2 AAA domain Ras PF00071.17 CBZ50682.1 - 0.0022 17.4 0.0 0.58 9.5 0.0 3.1 2 1 0 2 2 2 1 Ras family ABC_tran PF00005.22 CBZ50682.1 - 0.0025 18.1 0.0 1.4 9.1 0.0 2.6 2 0 0 2 2 2 1 ABC transporter SRPRB PF09439.5 CBZ50682.1 - 0.003 16.8 0.0 3 7.0 0.0 3.0 3 0 0 3 3 3 1 Signal recognition particle receptor beta subunit Arf PF00025.16 CBZ50682.1 - 0.0035 16.5 0.0 15 4.7 0.0 3.6 3 0 0 3 3 3 0 ADP-ribosylation factor family MCM PF00493.18 CBZ50682.1 - 0.0037 16.1 0.0 0.064 12.0 0.0 2.2 2 0 0 2 2 2 1 MCM2/3/5 family cobW PF02492.14 CBZ50682.1 - 0.0037 16.7 0.8 0.59 9.5 0.1 3.5 2 2 1 3 3 3 1 CobW/HypB/UreG, nucleotide-binding domain Arch_ATPase PF01637.13 CBZ50682.1 - 0.0042 16.8 0.2 3.9 7.1 0.0 3.0 3 1 1 4 4 4 1 Archaeal ATPase AAA_22 PF13401.1 CBZ50682.1 - 0.0076 16.3 0.0 3.2 7.8 0.0 3.1 2 2 0 2 2 2 1 AAA domain GBP PF02263.14 CBZ50682.1 - 0.017 14.1 0.0 0.041 12.9 0.0 1.6 1 0 0 1 1 1 0 Guanylate-binding protein, N-terminal domain AAA_28 PF13521.1 CBZ50682.1 - 0.02 14.8 1.2 6.2 6.7 0.0 3.7 4 1 0 4 4 3 0 AAA domain FtsK_SpoIIIE PF01580.13 CBZ50682.1 - 0.024 14.0 0.0 0.18 11.2 0.0 2.3 2 1 1 3 3 3 0 FtsK/SpoIIIE family PduV-EutP PF10662.4 CBZ50682.1 - 0.034 13.6 0.0 14 5.1 0.0 3.1 3 1 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation RNA_helicase PF00910.17 CBZ50682.1 - 0.047 13.8 0.0 8.7 6.5 0.0 2.6 2 0 0 2 2 2 0 RNA helicase IstB_IS21 PF01695.12 CBZ50682.1 - 0.11 11.9 0.0 0.57 9.5 0.0 2.1 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_24 PF13479.1 CBZ50682.1 - 0.12 11.8 0.0 5 6.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain Fcf2 PF08698.6 CBZ50683.1 - 2.1e-13 50.1 0.0 6.9e-13 48.4 0.0 1.9 1 0 0 1 1 1 1 Fcf2 pre-rRNA processing DUF842 PF05811.8 CBZ50684.1 - 0.23 10.9 0.6 1.4 8.3 0.1 2.0 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF842) PseudoU_synth_1 PF01416.15 CBZ50685.1 - 2.2e-14 53.7 0.0 2.7e-06 27.7 0.0 4.7 4 1 0 4 4 4 3 tRNA pseudouridine synthase LRR_4 PF12799.2 CBZ50688.1 - 6.3e-20 70.3 23.6 7.3e-09 35.0 2.3 4.4 3 1 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.1 CBZ50688.1 - 7.2e-13 48.4 0.9 1.7e-12 47.2 0.6 1.6 1 0 0 1 1 1 1 Leucine-rich repeat LRR_8 PF13855.1 CBZ50688.1 - 1.8e-11 43.5 21.4 6.2e-07 29.0 6.0 3.8 1 1 3 4 4 4 3 Leucine rich repeat LRR_6 PF13516.1 CBZ50688.1 - 8.2e-05 22.2 20.6 0.061 13.4 0.7 6.1 4 1 2 6 6 6 3 Leucine Rich repeat LRR_1 PF00560.28 CBZ50688.1 - 0.002 17.9 23.4 0.19 11.8 0.7 5.8 6 0 0 6 6 6 2 Leucine Rich Repeat LRR_7 PF13504.1 CBZ50688.1 - 0.092 13.0 12.9 18 6.1 0.1 6.1 6 0 0 6 6 6 0 Leucine rich repeat RRM_1 PF00076.17 CBZ50689.1 - 2.1e-15 56.1 0.0 3.1e-15 55.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBZ50689.1 - 3e-10 39.8 0.0 4.6e-10 39.1 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBZ50689.1 - 4.5e-09 36.1 0.0 7.9e-09 35.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) SUI1 PF01253.17 CBZ50690.1 - 8.5e-12 44.7 0.0 1.9e-11 43.5 0.0 1.6 1 0 0 1 1 1 1 Translation initiation factor SUI1 DEAD PF00270.24 CBZ50691.1 - 1.8e-20 73.1 0.0 7.3e-12 45.1 0.0 3.2 2 1 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.26 CBZ50691.1 - 4.3e-18 64.9 0.0 1.3e-17 63.4 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 CBZ50691.1 - 1.6e-06 28.1 0.0 1.6e-06 28.1 0.0 3.2 4 0 0 4 4 4 1 Type III restriction enzyme, res subunit DUF605 PF04652.11 CBZ50691.1 - 3.6 6.8 37.4 0.17 11.2 13.9 2.6 2 0 0 2 2 2 0 Vta1 like ThiF PF00899.16 CBZ50692.1 - 0.12 12.2 0.0 0.17 11.7 0.0 1.2 1 0 0 1 1 1 0 ThiF family Coatomer_WDAD PF04053.9 CBZ50693.1 - 0.0093 14.7 0.0 2 7.1 0.0 2.1 1 1 1 2 2 2 2 Coatomer WD associated region Clathrin PF00637.15 CBZ50694.1 - 3.1e-09 36.5 0.7 0.16 11.5 0.0 5.7 5 2 0 5 5 5 3 Region in Clathrin and VPS Coatomer_WDAD PF04053.9 CBZ50694.1 - 1.2e-06 27.5 1.1 1.2e-06 27.5 0.7 2.6 3 0 0 3 3 3 1 Coatomer WD associated region TPR_7 PF13176.1 CBZ50694.1 - 2.3e-06 26.9 19.1 1.3 8.9 0.1 8.7 7 2 1 8 8 8 3 Tetratricopeptide repeat TPR_2 PF07719.12 CBZ50694.1 - 1.5e-05 24.5 37.9 0.024 14.5 0.6 9.8 10 3 3 13 13 11 2 Tetratricopeptide repeat TPR_11 PF13414.1 CBZ50694.1 - 2.7e-05 23.7 17.6 0.35 10.5 0.1 7.2 7 0 0 7 7 7 2 TPR repeat TPR_8 PF13181.1 CBZ50694.1 - 0.00027 20.4 13.6 0.21 11.4 0.2 5.6 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.23 CBZ50694.1 - 0.0004 19.8 28.0 0.053 13.1 0.2 7.6 6 1 1 7 7 7 3 Tetratricopeptide repeat TPR_14 PF13428.1 CBZ50694.1 - 0.014 15.9 40.4 2.5 8.9 0.8 10.7 9 3 4 13 13 11 0 Tetratricopeptide repeat PPR PF01535.15 CBZ50694.1 - 0.02 14.8 1.9 52 4.1 0.0 5.8 6 1 1 7 7 6 0 PPR repeat TPR_12 PF13424.1 CBZ50694.1 - 0.025 14.4 33.3 0.052 13.4 1.0 8.7 9 3 1 10 10 10 0 Tetratricopeptide repeat PseudoU_synth_2 PF00849.17 CBZ50694.1 - 0.06 13.1 0.2 0.11 12.3 0.2 1.4 1 0 0 1 1 1 0 RNA pseudouridylate synthase RPN7 PF10602.4 CBZ50694.1 - 0.082 12.2 5.3 3.9 6.8 0.0 4.5 4 2 1 5 5 5 0 26S proteasome subunit RPN7 MIT PF04212.13 CBZ50694.1 - 0.19 11.5 0.1 0.19 11.5 0.0 4.8 5 0 0 5 5 5 0 MIT (microtubule interacting and transport) domain Apc3 PF12895.2 CBZ50694.1 - 0.89 9.7 17.8 0.79 9.9 0.2 5.5 6 1 0 6 6 5 0 Anaphase-promoting complex, cyclosome, subunit 3 DUF21 PF01595.15 CBZ50696.1 - 1.3e-30 106.0 0.3 2.2e-30 105.3 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function DUF21 CBS PF00571.23 CBZ50696.1 - 1.9e-06 27.5 0.5 0.018 14.7 0.0 2.6 2 0 0 2 2 2 2 CBS domain Peptidase_M24 PF00557.19 CBZ50698.1 - 2.7e-46 157.7 0.0 3.4e-46 157.4 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 RCC1_2 PF13540.1 CBZ50700.1 - 5.5e-08 32.2 0.1 1.6e-05 24.4 0.1 2.9 2 0 0 2 2 2 2 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.13 CBZ50700.1 - 0.00089 19.4 1.4 2.5 8.3 0.0 3.6 3 0 0 3 3 3 2 Regulator of chromosome condensation (RCC1) repeat DNA_pol3_a_NII PF11490.3 CBZ50700.1 - 7.3 6.2 5.4 15 5.2 3.7 1.5 1 0 0 1 1 1 0 DNA polymerase III polC-type N-terminus II YbjQ_1 PF01906.12 CBZ50701.1 - 1.3e-25 89.8 0.9 1.8e-25 89.3 0.6 1.2 1 0 0 1 1 1 1 Putative heavy-metal-binding DUF4156 PF13698.1 CBZ50701.1 - 0.01 15.6 0.0 0.02 14.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4156) DUF2407 PF10302.4 CBZ50703.1 - 0.04 14.0 0.0 0.088 13.0 0.0 1.6 2 0 0 2 2 2 0 DUF2407 ubiquitin-like domain ubiquitin PF00240.18 CBZ50703.1 - 0.12 11.7 0.2 0.27 10.6 0.1 1.6 1 0 0 1 1 1 0 Ubiquitin family DNA_ligase_A_N PF04675.9 CBZ50704.1 - 0.053 13.3 0.0 0.12 12.1 0.0 1.6 1 0 0 1 1 1 0 DNA ligase N terminus Big_5 PF13205.1 CBZ50705.1 - 5.4e-09 36.6 1.5 0.016 15.7 0.1 4.7 4 0 0 4 4 4 3 Bacterial Ig-like domain Notch PF00066.12 CBZ50705.1 - 8.2e-06 25.9 9.4 8.2e-06 25.9 6.5 3.6 4 0 0 4 4 4 1 LNR domain OmdA PF13376.1 CBZ50705.1 - 0.25 11.0 0.0 0.69 9.6 0.0 1.7 1 0 0 1 1 1 0 Bacteriocin-protection, YdeI or OmpD-Associated Pkinase PF00069.20 CBZ50706.1 - 1.7e-05 24.1 0.0 2.7e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.1 CBZ50706.1 - 0.00045 19.2 0.0 0.0014 17.6 0.0 1.7 1 1 0 1 1 1 1 Kinase-like PTH2 PF01981.11 CBZ50708.1 - 1.1e-46 157.2 0.1 1.6e-46 156.7 0.0 1.2 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 Myc_N PF01056.13 CBZ50708.1 - 0.061 12.4 0.0 0.08 12.1 0.0 1.2 1 0 0 1 1 1 0 Myc amino-terminal region IF-2B PF01008.12 CBZ50709.1 - 7.7e-41 139.9 0.0 1.7e-40 138.8 0.0 1.5 1 1 0 1 1 1 1 Initiation factor 2 subunit family AAA_16 PF13191.1 CBZ50710.1 - 4.9e-05 23.4 4.9 0.00014 21.9 1.6 3.0 1 1 1 2 2 2 1 AAA ATPase domain Zeta_toxin PF06414.7 CBZ50710.1 - 0.00016 20.8 0.1 0.00069 18.7 0.0 2.0 1 1 0 1 1 1 1 Zeta toxin ORC4_C PF14629.1 CBZ50710.1 - 0.00023 20.6 1.8 0.013 14.9 0.0 2.8 2 0 0 2 2 2 1 Origin recognition complex (ORC) subunit 4 C-terminus AAA_22 PF13401.1 CBZ50710.1 - 0.00031 20.8 0.1 0.0075 16.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 CBZ50710.1 - 0.0021 17.7 0.0 0.0066 16.1 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA PF00004.24 CBZ50710.1 - 0.0023 18.1 0.0 0.13 12.4 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 CBZ50710.1 - 0.0029 17.2 0.2 0.81 9.3 0.0 2.9 2 1 0 2 2 2 1 NACHT domain ABC_tran PF00005.22 CBZ50710.1 - 0.0092 16.2 0.0 0.019 15.2 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_33 PF13671.1 CBZ50710.1 - 0.016 15.0 0.0 0.046 13.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain Pam16 PF03656.8 CBZ50710.1 - 0.02 14.6 0.6 0.02 14.6 0.4 2.1 2 0 0 2 2 1 0 Pam16 TEX19 PF15553.1 CBZ50710.1 - 0.055 13.3 0.1 0.34 10.7 0.0 2.3 1 0 0 1 1 1 0 Testis-expressed protein 19 IstB_IS21 PF01695.12 CBZ50710.1 - 0.058 12.8 0.0 0.13 11.6 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_24 PF13479.1 CBZ50710.1 - 0.068 12.7 0.2 0.14 11.6 0.0 1.6 1 1 0 1 1 1 0 AAA domain T2SE PF00437.15 CBZ50710.1 - 0.083 11.7 0.0 0.15 10.9 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein Arch_ATPase PF01637.13 CBZ50710.1 - 0.1 12.2 0.0 0.24 11.0 0.0 1.6 1 1 0 1 1 1 0 Archaeal ATPase cobW PF02492.14 CBZ50710.1 - 0.16 11.4 0.0 0.29 10.5 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_11 PF13086.1 CBZ50710.1 - 0.16 11.5 1.6 0.25 10.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.1 CBZ50710.1 - 0.16 11.8 0.0 0.33 10.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain Aminotran_5 PF00266.14 CBZ50712.1 - 2.5e-79 266.7 0.0 2.8e-58 197.4 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class-V Beta_elim_lyase PF01212.16 CBZ50712.1 - 8.1e-09 35.0 0.1 2.3e-08 33.5 0.0 1.6 1 1 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.12 CBZ50712.1 - 7.2e-06 25.2 0.0 1.7e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Pyridoxal_deC PF00282.14 CBZ50712.1 - 0.00013 20.5 0.0 0.00021 19.8 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain AAA PF00004.24 CBZ50714.1 - 3.1e-14 53.3 0.0 1.2e-13 51.4 0.0 2.1 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 CBZ50714.1 - 0.00059 20.6 0.1 0.0053 17.5 0.0 2.8 2 1 0 2 2 1 1 AAA domain AAA_22 PF13401.1 CBZ50714.1 - 0.0023 18.0 0.1 0.055 13.6 0.0 3.2 2 2 1 3 3 3 1 AAA domain RuvB_N PF05496.7 CBZ50714.1 - 0.0036 16.3 0.0 0.0079 15.2 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus IQ PF00612.22 CBZ50714.1 - 0.0045 16.5 3.3 0.013 15.1 2.3 1.8 1 0 0 1 1 1 1 IQ calmodulin-binding motif AAA_16 PF13191.1 CBZ50714.1 - 0.013 15.5 3.0 0.035 14.0 0.0 2.9 3 0 0 3 3 3 0 AAA ATPase domain SKI PF01202.17 CBZ50714.1 - 0.016 15.0 0.1 0.2 11.5 0.0 2.7 2 1 1 3 3 3 0 Shikimate kinase AAA_18 PF13238.1 CBZ50714.1 - 0.027 14.7 0.0 0.14 12.4 0.0 2.4 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.1 CBZ50714.1 - 0.035 13.9 0.0 0.12 12.3 0.0 2.0 1 1 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 CBZ50714.1 - 0.069 12.2 0.0 0.15 11.2 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_19 PF13245.1 CBZ50714.1 - 0.089 12.5 0.0 0.32 10.7 0.0 2.0 1 0 0 1 1 1 0 Part of AAA domain Torsin PF06309.6 CBZ50714.1 - 0.091 12.6 0.0 0.23 11.3 0.0 1.6 1 0 0 1 1 1 0 Torsin AAA_5 PF07728.9 CBZ50714.1 - 0.11 12.2 0.0 0.29 10.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) RNA_helicase PF00910.17 CBZ50714.1 - 0.12 12.5 0.0 0.26 11.4 0.0 1.6 1 0 0 1 1 1 0 RNA helicase Sec61_beta PF03911.11 CBZ50715.1 - 2.3e-19 68.9 0.0 2.8e-19 68.6 0.0 1.1 1 0 0 1 1 1 1 Sec61beta family RRM_1 PF00076.17 CBZ50717.1 - 2.8e-16 58.9 0.0 4.5e-16 58.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBZ50717.1 - 5.5e-16 58.3 0.0 1.1e-15 57.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBZ50717.1 - 7.8e-08 32.0 0.3 1.7e-07 30.9 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 CBZ50717.1 - 0.033 13.9 0.0 0.068 12.9 0.0 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif DUF3138 PF11336.3 CBZ50717.1 - 0.047 11.8 0.1 0.065 11.4 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) ScpA_ScpB PF02616.9 CBZ50719.1 - 0.42 10.1 0.0 0.86 9.1 0.0 1.4 1 0 0 1 1 1 0 ScpA/B protein LUC7 PF03194.10 CBZ50720.1 - 1.7e-55 188.3 6.9 1.7e-55 188.3 4.8 2.6 3 0 0 3 3 3 1 LUC7 N_terminus AAA PF00004.24 CBZ50721.1 - 2.3e-14 53.7 0.0 3.9e-14 52.9 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.1 CBZ50721.1 - 3.8e-13 49.4 0.0 1.4e-10 41.0 0.0 2.2 1 1 1 2 2 2 1 DNA polymerase III, delta subunit Rep_fac_C PF08542.6 CBZ50721.1 - 1.3e-11 44.3 0.0 2.6e-11 43.3 0.0 1.6 1 0 0 1 1 1 1 Replication factor C C-terminal domain RuvB_N PF05496.7 CBZ50721.1 - 7e-08 31.8 0.3 2.6e-06 26.6 0.2 2.7 1 1 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 CBZ50721.1 - 3.1e-07 30.3 0.0 5.2e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.10 CBZ50721.1 - 4.1e-06 25.7 0.1 0.0065 15.2 0.0 2.2 2 0 0 2 2 2 2 Rad17 cell cycle checkpoint protein AAA_16 PF13191.1 CBZ50721.1 - 7.6e-06 26.0 0.5 0.0013 18.7 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 CBZ50721.1 - 1.2e-05 25.5 1.0 0.062 13.4 0.2 2.5 1 1 1 2 2 2 2 AAA domain Mg_chelatase PF01078.16 CBZ50721.1 - 3.1e-05 23.2 0.1 0.00084 18.5 0.0 2.2 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 CBZ50721.1 - 4.8e-05 23.1 0.1 0.00016 21.4 0.1 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_10 PF12846.2 CBZ50721.1 - 7.4e-05 22.3 0.5 0.12 11.7 0.0 2.6 1 1 1 2 2 2 2 AAA-like domain AAA_19 PF13245.1 CBZ50721.1 - 0.00016 21.3 0.0 0.00052 19.7 0.0 2.0 2 1 0 2 2 1 1 Part of AAA domain AAA_3 PF07726.6 CBZ50721.1 - 0.00026 20.6 0.0 0.00063 19.3 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 CBZ50721.1 - 0.0007 19.0 0.2 0.0039 16.6 0.2 2.2 1 1 1 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.13 CBZ50721.1 - 0.00078 18.9 0.1 0.043 13.2 0.0 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family MCM PF00493.18 CBZ50721.1 - 0.0033 16.2 0.0 0.0066 15.2 0.0 1.4 1 0 0 1 1 1 1 MCM2/3/5 family DEAD PF00270.24 CBZ50721.1 - 0.0037 16.7 0.4 0.1 12.1 0.1 2.5 1 1 0 2 2 2 1 DEAD/DEAH box helicase Sigma54_activ_2 PF14532.1 CBZ50721.1 - 0.0042 17.1 0.0 0.011 15.8 0.0 1.7 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_11 PF13086.1 CBZ50721.1 - 0.0047 16.5 0.0 0.0069 15.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain SNF2_N PF00176.18 CBZ50721.1 - 0.0053 15.5 0.1 3.1 6.5 0.0 2.8 1 1 2 3 3 3 1 SNF2 family N-terminal domain Viral_helicase1 PF01443.13 CBZ50721.1 - 0.0076 15.8 0.0 0.014 14.9 0.0 1.4 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase DNA_pol3_delta PF06144.8 CBZ50721.1 - 0.012 15.0 0.0 0.022 14.2 0.0 1.3 1 0 0 1 1 1 0 DNA polymerase III, delta subunit IstB_IS21 PF01695.12 CBZ50721.1 - 0.021 14.2 0.0 0.066 12.6 0.0 1.8 2 1 0 2 2 2 0 IstB-like ATP binding protein NTPase_1 PF03266.10 CBZ50721.1 - 0.023 14.3 0.7 3.5 7.3 0.0 3.0 1 1 1 2 2 2 0 NTPase Tap-RNA_bind PF09162.5 CBZ50721.1 - 0.049 13.2 0.0 0.13 11.8 0.0 1.7 2 0 0 2 2 1 0 Tap, RNA-binding Arch_ATPase PF01637.13 CBZ50721.1 - 0.062 12.9 0.0 5 6.7 0.0 2.1 1 1 1 2 2 2 0 Archaeal ATPase TIP49 PF06068.8 CBZ50721.1 - 0.067 11.9 0.0 0.97 8.0 0.0 2.1 2 0 0 2 2 2 0 TIP49 C-terminus AAA_33 PF13671.1 CBZ50721.1 - 0.1 12.4 0.0 0.22 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 CBZ50721.1 - 0.11 12.7 0.0 0.42 10.8 0.0 2.0 1 1 0 1 1 1 0 RNA helicase DUF815 PF05673.8 CBZ50721.1 - 0.11 11.4 0.0 0.18 10.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) CBM_14 PF01607.19 CBZ50722.1 - 0.072 13.0 0.4 0.072 13.0 0.3 10.1 8 3 2 10 10 10 0 Chitin binding Peritrophin-A domain Late_protein_L1 PF00500.13 CBZ50722.1 - 0.19 10.2 0.5 0.36 9.2 0.3 1.4 1 0 0 1 1 1 0 L1 (late) protein EGF_MSP1_1 PF12946.2 CBZ50722.1 - 1.4 8.7 10.2 3.3 7.5 0.0 5.8 5 2 1 6 6 6 0 MSP1 EGF domain 1 tRNA-synt_1d PF00750.14 CBZ50723.1 - 2.7e-106 355.3 0.2 1.1e-104 350.0 0.2 2.1 1 1 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.10 CBZ50723.1 - 1.9e-31 108.4 0.0 4.5e-31 107.2 0.0 1.7 1 0 0 1 1 1 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.11 CBZ50723.1 - 6.1e-13 49.1 0.1 2.1e-12 47.3 0.1 2.0 1 0 0 1 1 1 1 Arginyl tRNA synthetase N terminal domain tRNA-synt_1e PF01406.14 CBZ50723.1 - 0.0019 17.4 0.0 0.0054 15.8 0.0 1.8 1 1 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain SBP_bac_5 PF00496.17 CBZ50723.1 - 0.0021 16.9 0.0 0.0036 16.1 0.0 1.3 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 5 Middle tRNA-synt_1 PF00133.17 CBZ50723.1 - 0.036 12.0 0.1 0.063 11.2 0.0 1.3 1 0 0 1 1 1 0 tRNA synthetases class I (I, L, M and V) RIO1 PF01163.17 CBZ50724.1 - 1.1e-49 168.4 0.1 2.4e-25 88.9 0.0 2.6 2 0 0 2 2 2 2 RIO1 family DUF2457 PF10446.4 CBZ50724.1 - 0.00053 18.8 5.8 0.00053 18.8 4.0 4.1 4 0 0 4 4 4 1 Protein of unknown function (DUF2457) Spore_coat_CotO PF14153.1 CBZ50724.1 - 0.0019 17.6 4.4 0.0019 17.6 3.1 4.9 5 1 0 5 5 5 2 Spore coat protein CotO Daxx PF03344.10 CBZ50724.1 - 0.0027 16.2 16.5 0.0027 16.2 11.5 4.2 3 1 0 4 4 4 1 Daxx Family APH PF01636.18 CBZ50724.1 - 0.0048 16.6 2.5 0.0048 16.6 1.7 3.0 3 1 0 3 3 3 1 Phosphotransferase enzyme family DUF1510 PF07423.6 CBZ50724.1 - 6.7 6.0 54.6 0.17 11.2 11.6 4.4 4 0 0 4 4 4 0 Protein of unknown function (DUF1510) BOP1NT PF08145.7 CBZ50726.1 - 5.2e-89 298.4 0.4 5.2e-89 298.4 0.3 2.2 2 0 0 2 2 2 1 BOP1NT (NUC169) domain WD40 PF00400.27 CBZ50726.1 - 2.7e-20 71.4 5.6 1.6e-05 24.6 0.1 6.7 7 0 0 7 7 7 5 WD domain, G-beta repeat Apc4_WD40 PF12894.2 CBZ50726.1 - 0.2 11.1 0.0 28 4.3 0.0 2.5 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain ENTH PF01417.15 CBZ50728.1 - 4.3e-05 23.3 0.0 7.6e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 ENTH domain Cse1 PF08506.5 CBZ50728.1 - 0.5 8.8 0.1 0.73 8.3 0.1 1.1 1 0 0 1 1 1 0 Cse1 Maf PF02545.9 CBZ50730.1 - 2.7e-43 147.3 0.0 2.2e-39 134.6 0.0 2.2 2 0 0 2 2 2 2 Maf-like protein Pkinase PF00069.20 CBZ50731.1 - 1e-77 260.8 0.2 1.3e-77 260.4 0.2 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ50731.1 - 4.8e-42 143.8 0.0 6.6e-42 143.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_1 PF00036.27 CBZ50731.1 - 4.4e-28 94.3 9.1 4.8e-07 28.6 0.2 4.6 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 CBZ50731.1 - 8.8e-24 83.4 10.2 1.3e-10 41.2 0.6 3.5 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.1 CBZ50731.1 - 1e-22 77.9 5.0 4.2e-05 23.0 0.0 4.7 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 CBZ50731.1 - 3.6e-22 76.6 6.8 2.2e-05 23.5 0.0 4.5 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.1 CBZ50731.1 - 1.7e-17 62.7 10.7 0.00038 19.9 0.3 4.5 1 1 3 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.4 CBZ50731.1 - 3.3e-06 27.0 1.0 0.023 14.7 0.1 3.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region Kinase-like PF14531.1 CBZ50731.1 - 3.4e-06 26.2 0.1 0.0015 17.5 0.0 2.8 2 1 0 2 2 2 2 Kinase-like Kdo PF06293.9 CBZ50731.1 - 2.6e-05 23.4 0.1 9e-05 21.6 0.1 2.0 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family EF-hand_4 PF12763.2 CBZ50731.1 - 7.9e-05 22.3 8.1 0.013 15.2 0.6 3.9 2 1 2 4 4 4 2 Cytoskeletal-regulatory complex EF hand APH PF01636.18 CBZ50731.1 - 0.0085 15.8 0.0 0.023 14.4 0.0 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 CBZ50731.1 - 0.012 15.0 1.0 0.04 13.2 0.0 2.3 3 0 0 3 3 3 0 PhoP regulatory network protein YrbL NCD1 PF04904.8 CBZ50731.1 - 0.1 12.3 1.5 9.5 6.0 0.1 2.7 2 1 0 2 2 2 0 NAB conserved region 1 (NCD1) EF-hand_10 PF14788.1 CBZ50731.1 - 0.11 12.1 1.1 2.7 7.7 0.0 3.5 5 0 0 5 5 5 0 EF hand VCBS PF13517.1 CBZ50732.1 - 1.7e-20 73.0 14.4 2.8e-05 24.3 0.2 6.9 6 1 1 7 7 7 6 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.18 CBZ50732.1 - 1.9e-16 59.1 7.2 0.001 18.6 0.1 6.9 7 0 0 7 7 7 6 FG-GAP repeat TcdB_toxin_midN PF12256.3 CBZ50732.1 - 7e-05 22.3 0.0 0.16 11.4 0.0 3.9 4 0 0 4 4 4 1 Insecticide toxin TcdB middle/N-terminal region Spore_coat_CotO PF14153.1 CBZ50733.1 - 0.4 10.0 5.2 0.4 10.1 3.6 1.1 1 0 0 1 1 1 0 Spore coat protein CotO DUF1311 PF07007.7 CBZ50733.1 - 0.49 10.5 5.2 0.77 9.8 3.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1311) Reo_sigmaC PF04582.7 CBZ50734.1 - 2.3 7.3 7.5 8.8 5.4 0.1 2.2 2 0 0 2 2 2 0 Reovirus sigma C capsid protein Aha1_N PF09229.6 CBZ50736.1 - 6.7e-46 155.5 6.3 4.3e-23 81.6 0.0 2.4 3 0 0 3 3 3 2 Activator of Hsp90 ATPase, N-terminal Muted PF14942.1 CBZ50736.1 - 0.67 9.8 13.2 1.4 8.8 9.1 1.5 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein Atrophin-1 PF03154.10 CBZ50736.1 - 1.2 7.1 10.1 1.7 6.6 7.0 1.1 1 0 0 1 1 1 0 Atrophin-1 family Spc24 PF08286.6 CBZ50736.1 - 1.3 8.7 8.5 2.3 7.9 5.9 1.4 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 DUF1423 PF07227.6 CBZ50736.1 - 1.3 7.5 10.9 1.9 7.0 7.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1423) APG6 PF04111.7 CBZ50736.1 - 1.7 7.6 11.5 2.5 7.0 8.0 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 DHO_dh PF01180.16 CBZ50737.1 - 1.1e-94 316.7 0.0 1.4e-94 316.3 0.0 1.1 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase UCH PF00443.24 CBZ50738.1 - 4.9e-32 111.1 0.0 2.1e-31 109.0 0.0 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase YccV-like PF08755.6 CBZ50738.1 - 5.1e-15 55.2 0.0 9.8e-15 54.3 0.0 1.4 1 0 0 1 1 1 1 Hemimethylated DNA-binding protein YccV like PRKCSH PF07915.8 CBZ50738.1 - 3.6e-14 53.3 0.3 2.7e-06 28.0 0.0 2.9 2 0 0 2 2 2 2 Glucosidase II beta subunit-like protein UCH_1 PF13423.1 CBZ50738.1 - 0.025 14.0 0.0 1.6 8.1 0.0 2.7 2 1 0 2 2 2 0 Ubiquitin carboxyl-terminal hydrolase Peptidase_C26 PF07722.8 CBZ50740.1 - 2.5e-23 82.6 0.0 3.3e-22 79.0 0.0 2.3 1 1 0 1 1 1 1 Peptidase C26 GATase PF00117.23 CBZ50740.1 - 8.2e-06 25.3 0.0 1.3e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I tRNA-synt_2d PF01409.15 CBZ50741.1 - 2e-33 115.6 0.0 3.6e-20 72.2 0.0 2.9 2 1 0 2 2 2 2 tRNA synthetases class II core domain (F) FDX-ACB PF03147.9 CBZ50741.1 - 1.1e-18 67.1 0.2 9.1e-18 64.2 0.1 2.4 2 1 0 2 2 2 1 Ferredoxin-fold anticodon binding domain AAA_2 PF07724.9 CBZ50742.1 - 7.4e-26 91.0 0.9 8.5e-19 68.1 0.0 3.5 3 0 0 3 3 3 2 AAA domain (Cdc48 subfamily) AAA PF00004.24 CBZ50742.1 - 2.8e-17 63.1 0.9 2.7e-07 30.8 0.0 2.9 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 CBZ50742.1 - 1.6e-08 34.4 0.1 3.6e-06 26.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 CBZ50742.1 - 2.5e-07 30.8 0.5 1.8e-05 24.8 0.1 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 CBZ50742.1 - 2.2e-06 27.8 0.2 0.0025 17.9 0.0 3.0 3 1 0 3 3 2 1 AAA domain MCM PF00493.18 CBZ50742.1 - 5.8e-06 25.3 0.0 0.0015 17.3 0.0 2.2 2 0 0 2 2 2 1 MCM2/3/5 family ClpB_D2-small PF10431.4 CBZ50742.1 - 7.4e-06 25.7 0.2 2.8e-05 23.9 0.2 2.0 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_17 PF13207.1 CBZ50742.1 - 0.0001 23.1 0.0 0.00027 21.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.1 CBZ50742.1 - 0.00063 19.7 1.6 0.0027 17.6 0.0 2.8 3 0 0 3 3 3 1 AAA domain AAA_33 PF13671.1 CBZ50742.1 - 0.00069 19.5 0.1 0.0031 17.3 0.0 2.2 2 0 0 2 2 1 1 AAA domain Mg_chelatase PF01078.16 CBZ50742.1 - 0.00073 18.7 0.1 0.0061 15.7 0.0 2.5 4 0 0 4 4 4 1 Magnesium chelatase, subunit ChlI AAA_25 PF13481.1 CBZ50742.1 - 0.0014 18.0 0.3 0.071 12.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 CBZ50742.1 - 0.002 17.8 0.0 0.34 10.5 0.0 2.6 2 0 0 2 2 2 1 NACHT domain RuvB_N PF05496.7 CBZ50742.1 - 0.0034 16.4 0.0 0.013 14.5 0.0 1.9 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_18 PF13238.1 CBZ50742.1 - 0.0043 17.3 0.0 0.012 15.9 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 CBZ50742.1 - 0.0077 16.1 0.0 2.5 8.0 0.0 2.7 2 1 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 CBZ50742.1 - 0.0095 15.3 0.0 0.019 14.3 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.8 CBZ50742.1 - 0.011 14.5 0.1 0.02 13.6 0.0 1.3 1 0 0 1 1 1 0 TIP49 C-terminus Arch_ATPase PF01637.13 CBZ50742.1 - 0.014 15.0 0.0 0.37 10.4 0.0 2.3 2 0 0 2 2 2 0 Archaeal ATPase Zeta_toxin PF06414.7 CBZ50742.1 - 0.016 14.3 0.0 0.034 13.2 0.0 1.6 1 1 0 1 1 1 0 Zeta toxin PduV-EutP PF10662.4 CBZ50742.1 - 0.017 14.5 0.1 0.13 11.7 0.0 2.4 2 1 1 3 3 3 0 Ethanolamine utilisation - propanediol utilisation AAA_19 PF13245.1 CBZ50742.1 - 0.018 14.7 1.3 0.053 13.2 0.1 2.5 3 1 0 3 3 2 0 Part of AAA domain Rad17 PF03215.10 CBZ50742.1 - 0.041 12.5 0.0 0.078 11.6 0.0 1.4 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein DUF258 PF03193.11 CBZ50742.1 - 0.052 12.7 0.0 0.1 11.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 RNA_helicase PF00910.17 CBZ50742.1 - 0.054 13.6 0.0 0.33 11.1 0.0 2.3 2 0 0 2 2 2 0 RNA helicase ABC_tran PF00005.22 CBZ50742.1 - 0.088 13.1 0.1 0.36 11.1 0.1 2.0 1 1 0 1 1 1 0 ABC transporter Sigma54_activ_2 PF14532.1 CBZ50742.1 - 0.096 12.7 0.0 0.48 10.4 0.0 2.1 1 1 0 2 2 2 0 Sigma-54 interaction domain AAA-ATPase_like PF09820.4 CBZ50742.1 - 0.097 11.8 0.0 0.23 10.6 0.0 1.5 1 0 0 1 1 1 0 Predicted AAA-ATPase FokI_C PF02980.11 CBZ50742.1 - 0.13 11.8 0.1 0.27 10.9 0.0 1.4 1 0 0 1 1 1 0 Restriction endonuclease FokI, catalytic domain G-alpha PF00503.15 CBZ50742.1 - 0.14 10.7 0.0 0.19 10.3 0.0 1.3 1 1 0 1 1 1 0 G-protein alpha subunit ATG_C PF09333.6 CBZ50743.1 - 6e-06 26.3 0.0 1.7e-05 24.9 0.0 1.8 1 0 0 1 1 1 1 ATG C terminal domain Chorein_N PF12624.2 CBZ50743.1 - 2.9e-05 23.6 0.0 0.00051 19.5 0.0 2.3 2 0 0 2 2 2 1 N-terminal region of Chorein, a TM vesicle-mediated sorter OTU PF02338.14 CBZ50744.1 - 1.2e-11 45.2 0.1 5.6e-11 43.0 0.1 1.9 1 1 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.4 CBZ50744.1 - 0.0053 16.1 0.1 0.43 9.8 0.0 2.1 2 0 0 2 2 2 2 Peptidase C65 Otubain Ribosomal_S6e PF01092.14 CBZ50745.1 - 2.5e-52 175.8 0.4 2.5e-52 175.8 0.3 1.7 2 0 0 2 2 2 1 Ribosomal protein S6e eIF-3_zeta PF05091.7 CBZ50746.1 - 9.9e-143 476.4 0.0 1e-77 261.9 0.0 3.0 2 1 1 3 3 3 3 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) ECH PF00378.15 CBZ50747.1 - 4e-34 117.8 0.6 3.7e-29 101.5 0.2 2.1 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase family Peptidase_S49 PF01343.13 CBZ50747.1 - 0.093 12.5 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 Peptidase family S49 SDH_sah PF01972.11 CBZ50747.1 - 0.12 11.1 0.0 0.16 10.6 0.0 1.2 1 0 0 1 1 1 0 Serine dehydrogenase proteinase Pkinase PF00069.20 CBZ50748.1 - 9.9e-50 169.0 0.0 1.3e-35 122.8 0.0 3.2 2 1 1 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ50748.1 - 3.1e-21 75.6 0.0 6.2e-14 51.6 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase EF-hand_1 PF00036.27 CBZ50748.1 - 2.3e-16 57.7 3.8 0.00018 20.6 0.0 4.4 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 CBZ50748.1 - 1.7e-15 56.8 5.2 2.3e-07 30.8 0.7 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 CBZ50748.1 - 3.7e-13 48.1 4.5 0.00034 20.2 0.1 4.5 4 0 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.1 CBZ50748.1 - 1.4e-08 33.6 0.7 0.0051 16.0 0.0 3.6 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.1 CBZ50748.1 - 2.6e-08 33.3 4.4 0.077 12.6 0.1 4.1 3 1 1 4 4 4 3 EF-hand domain pair Kdo PF06293.9 CBZ50748.1 - 0.031 13.3 0.2 0.08 11.9 0.0 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family EF-hand_4 PF12763.2 CBZ50748.1 - 0.33 10.7 0.4 15 5.3 0.0 2.6 2 0 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand FYVE PF01363.16 CBZ50749.1 - 2.9e-18 65.5 8.5 6e-18 64.5 5.9 1.5 1 0 0 1 1 1 1 FYVE zinc finger Atg14 PF10186.4 CBZ50749.1 - 4.2e-06 25.9 9.1 4.2e-06 25.9 6.3 1.9 2 0 0 2 2 2 1 UV radiation resistance protein and autophagy-related subunit 14 CorA PF01544.13 CBZ50749.1 - 0.022 13.8 2.4 0.033 13.2 1.7 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Reo_sigmaC PF04582.7 CBZ50749.1 - 0.03 13.5 1.3 0.064 12.4 0.9 1.5 1 0 0 1 1 1 0 Reovirus sigma C capsid protein IBR PF01485.16 CBZ50749.1 - 0.038 13.8 5.1 0.082 12.7 3.5 1.5 1 0 0 1 1 1 0 IBR domain DUF3138 PF11336.3 CBZ50749.1 - 1.2 7.2 5.9 0.93 7.5 0.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3138) zf-B_box PF00643.19 CBZ50749.1 - 1.6 8.6 10.9 3.7 7.5 4.9 2.3 2 0 0 2 2 2 0 B-box zinc finger V_ATPase_I PF01496.14 CBZ50749.1 - 2.5 5.8 5.6 3.7 5.2 3.9 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family FUSC PF04632.7 CBZ50749.1 - 4.9 5.4 11.4 7.3 4.8 7.9 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family SlyX PF04102.7 CBZ50749.1 - 6.9 7.1 14.6 1.4 9.3 2.7 3.1 1 1 1 2 2 2 0 SlyX Fib_alpha PF08702.5 CBZ50749.1 - 9.1 6.3 9.2 21 5.2 6.4 1.6 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Pkinase PF00069.20 CBZ50750.1 - 3.4e-50 170.6 0.0 1.6e-20 73.3 0.0 3.3 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ50750.1 - 2.9e-26 92.1 0.0 4.3e-15 55.5 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase PH PF00169.24 CBZ50750.1 - 3.3e-07 30.4 0.0 2e-06 27.9 0.0 2.3 2 0 0 2 2 2 1 PH domain EF-hand_6 PF13405.1 CBZ50750.1 - 0.0072 16.1 1.7 0.0072 16.1 1.2 2.2 2 0 0 2 2 2 1 EF-hand domain EF-hand_8 PF13833.1 CBZ50750.1 - 0.0092 15.5 3.1 0.013 15.1 0.7 2.2 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_7 PF13499.1 CBZ50750.1 - 0.039 14.0 2.4 0.063 13.4 0.2 2.4 2 1 1 3 3 3 0 EF-hand domain pair EF-hand_1 PF00036.27 CBZ50750.1 - 0.14 11.5 7.4 0.052 12.8 2.4 2.2 2 0 0 2 2 2 0 EF hand Pox_ser-thr_kin PF05445.6 CBZ50750.1 - 1.5 7.5 0.0 2.2 6.9 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase DNA_pol_A PF00476.15 CBZ50752.1 - 7.4e-55 186.1 0.0 1.5e-41 142.3 0.0 4.0 3 2 0 3 3 3 3 DNA polymerase family A Snapin_Pallidin PF14712.1 CBZ50754.1 - 0.015 15.6 0.4 0.069 13.4 0.0 2.4 2 0 0 2 2 2 0 Snapin/Pallidin PTPS PF01242.14 CBZ50754.1 - 0.027 14.1 0.2 0.32 10.6 0.0 2.3 2 0 0 2 2 2 0 6-pyruvoyl tetrahydropterin synthase DUF998 PF06197.8 CBZ50754.1 - 0.26 10.5 7.3 0.22 10.8 0.1 3.4 4 0 0 4 4 4 0 Protein of unknown function (DUF998) PAN_1 PF00024.21 CBZ50757.1 - 1.5e-63 210.5 70.6 2.3e-06 27.2 2.0 10.5 10 0 0 10 10 10 10 PAN domain PAN_4 PF14295.1 CBZ50757.1 - 1.5e-46 155.8 74.9 2.7e-05 23.8 0.7 11.0 10 0 0 10 10 10 10 PAN domain TUG-UBL1 PF11470.3 CBZ50757.1 - 8.8e-07 28.7 7.0 15 5.6 0.0 5.5 5 0 0 5 5 5 5 GLUT4 regulating protein TUG HOK_GEF PF01848.11 CBZ50757.1 - 3.1e-06 26.3 1.6 29 4.0 0.0 5.3 5 0 0 5 5 5 0 Hok/gef family Mastoparan PF08249.6 CBZ50757.1 - 0.00087 19.6 7.4 92 3.9 0.0 5.4 5 0 0 5 5 5 0 Mastoparan protein IF3_C PF00707.17 CBZ50757.1 - 0.0082 15.8 6.8 84 3.0 0.0 5.1 5 0 0 5 5 5 0 Translation initiation factor IF-3, C-terminal domain ATP-sulfurylase PF01747.12 CBZ50757.1 - 0.17 11.2 1.2 72 2.5 0.0 4.0 5 0 0 5 5 5 0 ATP-sulfurylase Adenylsucc_synt PF00709.16 CBZ50758.1 - 1.3e-151 505.0 0.0 1.5e-151 504.8 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase PA14 PF07691.7 CBZ50759.1 - 3.7e-15 55.8 0.0 9.5e-14 51.2 0.0 3.0 4 0 0 4 4 4 1 PA14 domain NifU PF01106.12 CBZ50759.1 - 0.021 14.6 0.3 1.4 8.7 0.0 2.5 2 0 0 2 2 2 0 NifU-like domain cwf18 PF08315.7 CBZ50760.1 - 1.6e-25 90.0 0.7 1.6e-25 90.0 0.5 1.7 2 0 0 2 2 2 1 cwf18 pre-mRNA splicing factor SCP1201-deam PF14428.1 CBZ50760.1 - 0.014 15.0 0.1 0.026 14.2 0.0 1.4 1 1 0 1 1 1 0 SCP1.201-like deaminase PAN_4 PF14295.1 CBZ50763.1 - 0.00032 20.3 11.8 0.045 13.4 3.0 2.7 2 0 0 2 2 2 2 PAN domain PAN_1 PF00024.21 CBZ50763.1 - 0.0008 19.1 13.8 0.07 12.8 4.9 2.3 2 0 0 2 2 2 2 PAN domain Glutaredoxin PF00462.19 CBZ50764.1 - 6.3e-17 61.3 0.1 8.2e-17 60.9 0.1 1.2 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_4 PF13462.1 CBZ50764.1 - 7.6e-05 22.7 0.3 0.019 15.0 0.3 2.1 1 1 1 2 2 2 2 Thioredoxin Thioredoxin_3 PF13192.1 CBZ50764.1 - 0.00017 21.3 0.0 0.00029 20.6 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin domain Thioredoxin_2 PF13098.1 CBZ50764.1 - 0.00026 21.1 0.5 0.00085 19.5 0.3 1.8 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_9 PF14595.1 CBZ50764.1 - 0.00032 20.2 0.0 0.00039 19.9 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin DUF836 PF05768.9 CBZ50764.1 - 0.00097 19.3 0.0 0.0013 18.9 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) DSBA PF01323.15 CBZ50764.1 - 0.0021 17.6 1.4 0.058 12.9 0.1 2.1 1 1 1 2 2 2 1 DSBA-like thioredoxin domain Redoxin PF08534.5 CBZ50764.1 - 0.0091 15.5 0.0 0.011 15.2 0.0 1.2 1 0 0 1 1 1 1 Redoxin GST_N_3 PF13417.1 CBZ50764.1 - 0.019 15.1 0.0 0.026 14.7 0.0 1.2 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain DiS_P_DiS PF06750.8 CBZ50764.1 - 0.03 14.0 0.0 0.042 13.6 0.0 1.2 1 0 0 1 1 1 0 Bacterial Peptidase A24 N-terminal domain FANCL_C PF11793.3 CBZ50764.1 - 0.053 13.4 0.0 0.1 12.5 0.0 1.5 2 0 0 2 2 2 0 FANCL C-terminal domain TraF PF13728.1 CBZ50764.1 - 0.056 12.9 0.0 0.064 12.7 0.0 1.2 1 0 0 1 1 1 0 F plasmid transfer operon protein Thioredoxin_8 PF13905.1 CBZ50764.1 - 0.096 12.8 0.1 1.1 9.4 0.0 2.0 1 1 1 2 2 2 0 Thioredoxin-like Apo-CIII PF05778.7 CBZ50764.1 - 0.32 10.4 1.6 0.66 9.3 0.0 2.2 3 0 0 3 3 3 0 Apolipoprotein CIII (Apo-CIII) Peptidase_M24 PF00557.19 CBZ50765.1 - 3.2e-27 95.4 0.3 4.4e-27 95.0 0.2 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 DUF1749 PF08538.5 CBZ50766.1 - 1e-57 195.3 0.0 1.3e-57 195.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Abhydrolase_6 PF12697.2 CBZ50766.1 - 7e-15 55.5 0.0 1e-14 54.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CBZ50766.1 - 6.3e-10 38.9 0.0 1.2e-09 38.0 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF900 PF05990.7 CBZ50766.1 - 4.8e-05 22.7 0.0 7.6e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) DUF915 PF06028.6 CBZ50766.1 - 0.00018 20.6 0.0 0.00028 20.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) DUF2305 PF10230.4 CBZ50766.1 - 0.00079 18.9 0.0 0.24 10.7 0.0 2.1 1 1 1 2 2 2 2 Uncharacterised conserved protein (DUF2305) DLH PF01738.13 CBZ50766.1 - 0.00084 18.6 0.0 0.0016 17.8 0.0 1.4 1 0 0 1 1 1 1 Dienelactone hydrolase family FSH1 PF03959.8 CBZ50766.1 - 0.0049 16.3 0.0 0.02 14.3 0.0 1.8 1 1 0 1 1 1 1 Serine hydrolase (FSH1) VirJ PF06057.6 CBZ50766.1 - 0.014 15.1 0.0 0.046 13.4 0.0 1.8 2 0 0 2 2 2 0 Bacterial virulence protein (VirJ) Abhydrolase_1 PF00561.15 CBZ50766.1 - 0.055 13.0 0.0 1.8 8.0 0.0 2.1 1 1 0 1 1 1 0 alpha/beta hydrolase fold SNARE_assoc PF09335.6 CBZ50767.1 - 9.3e-16 58.1 7.0 9.3e-16 58.1 4.8 2.7 1 1 1 2 2 2 2 SNARE associated Golgi protein Osmo_CC PF08946.5 CBZ50769.1 - 0.0092 15.9 0.5 0.0092 15.9 0.3 2.4 3 0 0 3 3 3 1 Osmosensory transporter coiled coil RapA_C PF12137.3 CBZ50769.1 - 0.014 14.2 0.1 0.018 13.9 0.0 1.1 1 0 0 1 1 1 0 RNA polymerase recycling family C-terminal DUF4381 PF14316.1 CBZ50769.1 - 0.036 14.1 0.2 0.069 13.2 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) DUF2563 PF10817.3 CBZ50769.1 - 0.041 14.3 0.1 0.076 13.4 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2563) COX16 PF14138.1 CBZ50769.1 - 0.08 13.1 0.2 0.08 13.1 0.2 1.7 2 0 0 2 2 2 0 Cytochrome c oxidase assembly protein COX16 Topoisom_I_N PF02919.10 CBZ50769.1 - 0.16 11.2 0.5 0.26 10.5 0.2 1.4 1 1 0 1 1 1 0 Eukaryotic DNA topoisomerase I, DNA binding fragment VMA21 PF09446.5 CBZ50770.1 - 4.8e-07 29.6 4.0 4.3e-06 26.5 2.8 2.0 1 1 0 1 1 1 1 VMA21-like domain TRP PF06011.7 CBZ50770.1 - 0.0089 14.6 0.0 0.01 14.4 0.0 1.0 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel ESR1_C PF12743.2 CBZ50770.1 - 0.012 15.1 5.0 0.029 13.8 3.5 1.8 1 1 0 1 1 1 0 Oestrogen-type nuclear receptor final C-terminal ATP-synt_C PF00137.16 CBZ50770.1 - 0.033 14.0 0.1 0.072 13.0 0.1 1.5 1 0 0 1 1 1 0 ATP synthase subunit C Ly49 PF08391.5 CBZ50770.1 - 0.095 12.8 0.2 0.31 11.1 0.0 1.9 1 1 1 2 2 2 0 Ly49-like protein, N-terminal region DEAD PF00270.24 CBZ50771.1 - 1.2e-43 148.5 0.5 1.2e-43 148.5 0.3 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CBZ50771.1 - 1e-26 92.5 0.0 2.7e-26 91.2 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Helicase_RecD PF05127.9 CBZ50771.1 - 0.0088 15.6 0.3 0.052 13.1 0.0 2.5 3 1 0 3 3 3 1 Helicase ResIII PF04851.10 CBZ50771.1 - 0.0096 15.7 0.0 0.066 13.0 0.0 2.1 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C_4 PF13871.1 CBZ50771.1 - 0.046 13.1 0.4 1.6 8.0 0.1 2.4 2 0 0 2 2 2 0 Helicase_C-like AAA_22 PF13401.1 CBZ50771.1 - 0.6 10.2 3.6 2.3 8.3 0.6 3.0 2 1 0 2 2 2 0 AAA domain Rad60-SLD_2 PF13881.1 CBZ50773.1 - 1.1e-06 28.5 0.0 2.2e-06 27.5 0.0 1.4 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like DUF1391 PF07151.7 CBZ50773.1 - 0.039 13.4 0.0 0.063 12.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1391) ubiquitin PF00240.18 CBZ50773.1 - 0.041 13.2 0.0 0.27 10.6 0.0 1.9 2 0 0 2 2 2 0 Ubiquitin family YIEGIA PF14045.1 CBZ50774.1 - 0.1 11.2 0.5 0.18 10.4 0.3 1.3 1 0 0 1 1 1 0 YIEGIA protein FUSC PF04632.7 CBZ50774.1 - 0.48 8.7 24.6 0.0093 14.4 4.4 2.3 2 0 0 2 2 2 0 Fusaric acid resistance protein family TSA PF03249.8 CBZ50774.1 - 3 6.2 7.2 7.1 5.0 5.0 1.5 1 0 0 1 1 1 0 Type specific antigen DUF4239 PF14023.1 CBZ50774.1 - 9.5 5.5 10.5 1.8 7.8 0.4 2.8 1 1 1 3 3 3 0 Protein of unknown function (DUF4239) TPR_2 PF07719.12 CBZ50776.1 - 5.9e-11 41.4 1.5 3.2e-05 23.4 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 CBZ50776.1 - 1.8e-07 31.1 13.0 0.0027 18.2 0.0 4.7 4 2 0 4 4 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 CBZ50776.1 - 6.2e-07 28.9 0.1 0.013 15.1 0.0 3.4 3 0 0 3 3 3 2 TPR repeat TPR_9 PF13371.1 CBZ50776.1 - 7.1e-06 25.7 4.2 0.032 14.0 0.1 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.1 CBZ50776.1 - 1e-05 26.0 7.9 0.0074 16.9 0.0 4.4 4 1 1 5 5 4 2 Tetratricopeptide repeat TPR_7 PF13176.1 CBZ50776.1 - 0.00025 20.6 2.2 3.3 7.7 0.0 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.1 CBZ50776.1 - 0.00041 20.6 1.5 0.35 11.2 0.0 3.5 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.23 CBZ50776.1 - 0.00042 19.8 0.8 0.004 16.7 0.0 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.1 CBZ50776.1 - 0.00099 19.4 0.1 0.46 11.0 0.0 3.4 4 0 0 4 4 2 1 Tetratricopeptide repeat TPR_15 PF13429.1 CBZ50776.1 - 0.0012 17.9 0.2 0.0023 17.0 0.1 1.5 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_8 PF13181.1 CBZ50776.1 - 0.002 17.7 0.0 0.036 13.8 0.0 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.1 CBZ50776.1 - 0.022 14.9 1.3 2.9 8.3 0.0 4.2 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_12 PF13424.1 CBZ50776.1 - 0.031 14.2 2.2 2.9 7.8 0.0 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat ETF PF01012.16 CBZ50777.1 - 8.2e-30 103.6 0.0 1.2e-29 103.1 0.0 1.2 1 0 0 1 1 1 1 Electron transfer flavoprotein domain B12-binding PF02310.14 CBZ50777.1 - 0.044 13.6 0.0 0.093 12.6 0.0 1.5 1 0 0 1 1 1 0 B12 binding domain Ras PF00071.17 CBZ50779.1 - 2.5e-58 196.0 0.1 2.9e-58 195.8 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CBZ50779.1 - 9e-19 68.1 0.0 1.4e-18 67.4 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CBZ50779.1 - 5.5e-15 55.0 0.0 7.8e-15 54.5 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 CBZ50779.1 - 0.0013 18.2 0.0 0.0037 16.7 0.0 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 CBZ50779.1 - 0.0019 17.4 0.0 0.0023 17.0 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 CBZ50779.1 - 0.0033 17.3 0.0 0.005 16.7 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_M PF01031.15 CBZ50780.1 - 1.3e-105 352.4 0.0 2.1e-105 351.7 0.0 1.3 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.18 CBZ50780.1 - 9.2e-53 178.5 0.1 1.6e-52 177.6 0.0 1.4 1 0 0 1 1 1 1 Dynamin family GED PF02212.13 CBZ50780.1 - 3e-31 107.1 2.0 5.2e-31 106.3 0.6 2.1 3 0 0 3 3 3 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 CBZ50780.1 - 3.9e-05 23.5 0.0 0.00011 22.1 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 CBZ50780.1 - 0.0096 16.4 0.0 0.021 15.3 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein AAA_16 PF13191.1 CBZ50780.1 - 0.012 15.5 1.1 0.37 10.7 0.0 3.2 3 1 0 3 3 3 0 AAA ATPase domain AAA_28 PF13521.1 CBZ50780.1 - 0.051 13.5 0.3 0.33 10.9 0.0 2.1 1 1 1 2 2 2 0 AAA domain FeoB_N PF02421.13 CBZ50780.1 - 0.14 11.4 0.1 4.2 6.6 0.0 2.3 2 0 0 2 2 2 0 Ferrous iron transport protein B Ycf1 PF05758.7 CBZ50781.1 - 2 6.0 2.7 1.1 6.8 0.4 1.5 2 0 0 2 2 2 0 Ycf1 TRAP_alpha PF03896.11 CBZ50781.1 - 5.6 5.8 5.0 1.5 7.7 0.3 2.2 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit Sec62 PF03839.11 CBZ50781.1 - 9.9 5.4 0.3 25 4.1 0.2 1.6 1 0 0 1 1 1 0 Translocation protein Sec62 Laminin_I PF06008.9 CBZ50782.1 - 0.078 12.2 1.0 0.13 11.5 0.7 1.3 1 0 0 1 1 1 0 Laminin Domain I DUF1768 PF08719.6 CBZ50783.1 - 6e-17 61.8 0.0 1.2e-16 60.8 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) FHA PF00498.21 CBZ50783.1 - 1.6e-11 44.1 0.0 3.8e-11 42.9 0.0 1.7 1 0 0 1 1 1 1 FHA domain RRM_1 PF00076.17 CBZ50783.1 - 3.6e-11 42.5 0.0 2.7e-10 39.7 0.0 2.2 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBZ50783.1 - 8.3e-10 38.5 0.0 1.7e-09 37.5 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBZ50783.1 - 1.3e-08 34.5 0.0 3.4e-08 33.2 0.0 1.8 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ribophorin_II PF05817.9 CBZ50784.1 - 0.00015 20.1 0.0 0.00039 18.7 0.0 1.7 2 0 0 2 2 2 1 Oligosaccharyltransferase subunit Ribophorin II Gluconate_2-dh3 PF13618.1 CBZ50784.1 - 0.074 13.2 0.3 0.27 11.3 0.2 2.0 1 1 0 1 1 1 0 Gluconate 2-dehydrogenase subunit 3 Cyclin PF08613.6 CBZ50785.1 - 1.7e-32 112.9 0.4 3e-32 112.0 0.3 1.4 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 CBZ50785.1 - 5.2e-10 38.9 0.3 8.5e-10 38.2 0.2 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Tom37_C PF11801.3 CBZ50785.1 - 0.085 12.7 0.9 0.19 11.5 0.6 1.5 1 0 0 1 1 1 0 Tom37 C-terminal domain Apt1 PF10351.4 CBZ50786.1 - 3.4 6.4 3.8 9 5.0 2.6 1.6 1 0 0 1 1 1 0 Golgi-body localisation protein domain GCV_T PF01571.16 CBZ50787.1 - 0.0033 16.8 0.0 0.0083 15.5 0.0 1.6 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain LRR_4 PF12799.2 CBZ50788.1 - 1.6e-40 136.0 27.6 2.2e-08 33.4 0.2 7.1 3 1 5 8 8 8 8 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CBZ50788.1 - 8.8e-32 108.6 24.6 2.9e-11 42.9 1.1 4.8 4 1 1 5 5 5 4 Leucine rich repeat LRR_1 PF00560.28 CBZ50788.1 - 6.8e-19 64.9 16.9 0.0086 15.9 0.0 10.9 10 1 1 11 11 11 5 Leucine Rich Repeat LRR_6 PF13516.1 CBZ50788.1 - 1.2e-17 61.9 12.4 0.091 12.8 0.0 11.2 9 2 2 11 11 11 4 Leucine Rich repeat LRR_9 PF14580.1 CBZ50788.1 - 7e-17 61.5 8.7 0.00011 21.8 0.1 4.1 1 1 3 4 4 4 4 Leucine-rich repeat LRR_7 PF13504.1 CBZ50788.1 - 2.2e-12 45.0 23.7 0.2 11.9 0.0 11.6 12 1 1 13 13 13 2 Leucine rich repeat LRR_2 PF07723.8 CBZ50788.1 - 0.063 13.8 0.4 1.1e+02 3.5 0.0 5.0 6 0 0 6 6 6 0 Leucine Rich Repeat LRR_5 PF13306.1 CBZ50788.1 - 0.14 11.8 0.1 1.4 8.5 0.0 2.5 2 1 0 2 2 2 0 Leucine rich repeats (6 copies) Pkinase PF00069.20 CBZ50789.1 - 1.5e-69 234.0 0.0 2e-69 233.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ50789.1 - 2.4e-34 118.5 0.0 3.2e-34 118.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 CBZ50789.1 - 2.6e-05 24.6 0.0 0.0003 21.2 0.0 2.8 2 1 0 2 2 2 1 Protein kinase C terminal domain Kinase-like PF14531.1 CBZ50789.1 - 0.00018 20.5 0.0 0.00027 20.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APG17 PF04108.7 CBZ50790.1 - 0.047 12.4 0.0 0.098 11.4 0.0 1.5 1 0 0 1 1 1 0 Autophagy protein Apg17 SNARE PF05739.14 CBZ50790.1 - 0.048 13.3 1.4 0.2 11.3 0.1 2.4 2 0 0 2 2 2 0 SNARE domain zf-Apc11 PF12861.2 CBZ50791.1 - 9.7e-20 70.2 6.7 1.5e-19 69.6 4.6 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.2 CBZ50791.1 - 3.9e-19 68.5 8.0 7.2e-19 67.6 5.5 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 CBZ50791.1 - 6.5e-05 22.5 9.9 0.00014 21.4 5.0 2.4 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.1 CBZ50791.1 - 0.0002 21.1 13.4 0.00071 19.3 9.3 2.0 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 CBZ50791.1 - 0.0045 16.6 7.0 0.012 15.2 4.9 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CBZ50791.1 - 0.0097 15.9 8.0 0.07 13.1 5.6 2.3 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CBZ50791.1 - 0.017 14.8 12.6 0.041 13.5 7.4 2.3 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 CBZ50791.1 - 0.052 13.4 2.2 0.052 13.4 1.5 2.3 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-HC5HC2H PF13771.1 CBZ50791.1 - 3.7 7.7 8.7 13 5.9 6.2 1.9 1 1 1 2 2 2 0 PHD-like zinc-binding domain zf-RING_4 PF14570.1 CBZ50791.1 - 3.9 7.1 9.8 15 5.2 6.8 2.1 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-HIT PF04438.11 CBZ50791.1 - 6.2 6.5 10.1 1.2 8.8 3.3 2.4 2 0 0 2 2 2 0 HIT zinc finger PHD PF00628.24 CBZ50791.1 - 7.2 6.3 12.6 3.6e+02 0.9 8.7 2.5 1 1 0 1 1 1 0 PHD-finger Vma12 PF11712.3 CBZ50792.1 - 3.9e-10 39.5 0.0 8.8e-10 38.4 0.0 1.6 1 0 0 1 1 1 1 Endoplasmic reticulum-based factor for assembly of V-ATPase MFS_1 PF07690.11 CBZ50792.1 - 0.022 13.4 0.2 0.032 12.9 0.2 1.1 1 0 0 1 1 1 0 Major Facilitator Superfamily Ribosomal_L18e PF00828.14 CBZ50792.1 - 0.076 13.3 0.0 0.13 12.5 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L18e/L15 FtsX PF02687.16 CBZ50792.1 - 0.078 12.7 0.6 0.16 11.7 0.4 1.5 1 1 0 1 1 1 0 FtsX-like permease family DUF508 PF04370.7 CBZ50792.1 - 6.4 6.3 10.3 18 4.8 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF508) UIM PF02809.15 CBZ50793.1 - 0.065 12.8 0.2 0.16 11.6 0.1 1.7 1 0 0 1 1 1 0 Ubiquitin interaction motif SAM_1 PF00536.25 CBZ50793.1 - 0.14 12.3 0.0 0.31 11.2 0.0 1.5 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) Peptidase_C1 PF00112.18 CBZ50794.1 - 1.8e-08 34.5 0.9 1.5e-07 31.5 0.5 2.0 1 1 1 2 2 2 1 Papain family cysteine protease CathepsinC_exc PF08773.6 CBZ50794.1 - 0.0011 19.1 0.2 1.6 8.9 0.0 2.8 3 1 0 3 3 3 2 Cathepsin C exclusion domain Peptidase_C39_2 PF13529.1 CBZ50794.1 - 0.081 13.2 0.0 0.14 12.5 0.0 1.4 1 0 0 1 1 1 0 Peptidase_C39 like family Herpes_TK_C PF08465.5 CBZ50794.1 - 0.56 9.7 3.2 13 5.3 0.1 3.0 3 0 0 3 3 3 0 Thymidine kinase from Herpesvirus C-terminal TRM PF02005.11 CBZ50795.1 - 3.5e-104 348.7 0.1 4e-76 256.3 0.0 2.1 2 0 0 2 2 2 2 N2,N2-dimethylguanosine tRNA methyltransferase Methyltransf_26 PF13659.1 CBZ50795.1 - 5.2e-05 23.2 0.0 0.00022 21.2 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.11 CBZ50795.1 - 0.0091 15.6 0.0 0.018 14.6 0.0 1.4 1 0 0 1 1 1 1 Met-10+ like-protein PrmA PF06325.8 CBZ50795.1 - 0.0095 15.0 0.1 0.019 14.1 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.2 CBZ50795.1 - 0.07 13.7 0.0 17 6.0 0.0 2.5 2 0 0 2 2 2 0 Methyltransferase domain CSD PF00313.17 CBZ50796.1 - 1.6e-25 88.6 0.4 2.2e-25 88.2 0.3 1.2 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain OB_RNB PF08206.6 CBZ50796.1 - 0.00077 18.9 0.1 0.0019 17.6 0.1 1.8 1 1 0 1 1 1 1 Ribonuclease B OB domain S1 PF00575.18 CBZ50796.1 - 0.089 12.9 0.1 0.13 12.4 0.0 1.2 1 0 0 1 1 1 0 S1 RNA binding domain AP2 PF00847.15 CBZ50797.1 - 1.5e-11 44.2 0.7 3.7e-11 43.0 0.5 1.6 1 0 0 1 1 1 1 AP2 domain RCC1_2 PF13540.1 CBZ50798.1 - 8.7e-05 22.0 24.6 0.87 9.2 0.1 6.9 7 0 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat TSP_1 PF00090.14 CBZ50798.1 - 0.04 14.0 6.2 0.12 12.5 4.3 1.9 1 0 0 1 1 1 0 Thrombospondin type 1 domain zf-C3HC4_3 PF13920.1 CBZ50799.1 - 1.4e-16 59.8 12.2 2.8e-16 58.9 8.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CBZ50799.1 - 1.9e-07 31.0 13.8 3.9e-07 29.9 9.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CBZ50799.1 - 7.8e-06 25.6 12.2 1.9e-05 24.3 8.4 1.7 1 0 0 1 1 1 1 Ring finger domain zf-P11 PF03854.9 CBZ50799.1 - 0.00011 21.5 7.6 0.00023 20.5 5.3 1.5 1 0 0 1 1 1 1 P-11 zinc finger Prok-RING_4 PF14447.1 CBZ50799.1 - 0.0044 16.5 5.9 0.0044 16.5 4.1 1.9 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.1 CBZ50799.1 - 0.0072 16.0 11.7 0.018 14.7 8.1 1.7 1 0 0 1 1 1 1 zinc-RING finger domain RecR PF02132.10 CBZ50799.1 - 1.3 8.4 7.3 2.8 7.4 2.5 2.7 3 0 0 3 3 3 0 RecR protein zf-RING_4 PF14570.1 CBZ50799.1 - 2.6 7.6 10.1 5.5 6.6 7.0 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain DnaJ PF00226.26 CBZ50800.1 - 3.8e-16 58.5 0.0 8.7e-16 57.4 0.0 1.6 1 0 0 1 1 1 1 DnaJ domain HlyD PF00529.15 CBZ50800.1 - 0.0043 16.4 0.8 0.0043 16.4 0.5 1.6 1 1 0 1 1 1 1 HlyD family secretion protein Mago_nashi PF02792.9 CBZ50801.1 - 6.5e-82 272.3 0.6 7.3e-82 272.1 0.4 1.0 1 0 0 1 1 1 1 Mago nashi protein DUF3506 PF12014.3 CBZ50801.1 - 0.057 13.2 0.2 0.13 12.0 0.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF3506) LCCL PF03815.14 CBZ50802.1 - 1.7e-49 165.7 0.9 5.7e-24 83.9 0.1 3.6 3 0 0 3 3 3 3 LCCL domain Laminin_G_3 PF13385.1 CBZ50802.1 - 8.9e-13 48.7 0.0 1.9e-12 47.7 0.0 1.5 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily PLAT PF01477.18 CBZ50802.1 - 1.2e-06 28.9 0.0 2.3e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 PLAT/LH2 domain SRCR PF00530.13 CBZ50802.1 - 9e-06 25.9 2.3 0.019 15.2 0.7 2.9 2 0 0 2 2 2 2 Scavenger receptor cysteine-rich domain Rxt3 PF08642.5 CBZ50802.1 - 0.00042 20.5 0.0 0.27 11.4 0.0 2.6 2 1 1 3 3 3 2 Histone deacetylation protein Rxt3 Pentaxin PF00354.12 CBZ50802.1 - 0.022 14.1 0.0 0.041 13.3 0.0 1.4 1 0 0 1 1 1 0 Pentaxin family Ribosomal_L32e PF01655.13 CBZ50803.1 - 5.1e-48 161.6 1.0 6.4e-48 161.3 0.7 1.1 1 0 0 1 1 1 1 Ribosomal protein L32 RNA_pol_A_bac PF01000.21 CBZ50804.1 - 2.6e-29 101.6 0.0 4.3e-29 100.9 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 CBZ50804.1 - 6.9e-17 60.3 0.0 8.6e-17 60.0 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Fer4_9 PF13187.1 CBZ50804.1 - 0.0095 16.1 1.5 0.02 15.1 1.1 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_10 PF13237.1 CBZ50804.1 - 0.024 14.4 1.7 0.049 13.4 1.1 1.5 1 0 0 1 1 1 0 4Fe-4S dicluster domain Fer4_7 PF12838.2 CBZ50804.1 - 0.055 13.8 1.4 0.12 12.8 1.0 1.6 1 0 0 1 1 1 0 4Fe-4S dicluster domain Nuc_sug_transp PF04142.10 CBZ50805.1 - 2.2e-85 285.6 9.8 2.2e-85 285.6 6.8 2.0 2 0 0 2 2 2 1 Nucleotide-sugar transporter UAA PF08449.6 CBZ50805.1 - 7.4e-06 25.0 11.3 7.4e-06 25.0 7.9 1.9 2 1 0 2 2 2 1 UAA transporter family TPT PF03151.11 CBZ50805.1 - 1.9e-05 24.3 23.6 9.8e-05 22.0 6.5 2.7 2 2 0 2 2 2 2 Triose-phosphate Transporter family EmrE PF13536.1 CBZ50805.1 - 2.6e-05 24.4 7.7 2.6e-05 24.4 5.4 3.3 3 1 0 4 4 4 1 Multidrug resistance efflux transporter EamA PF00892.15 CBZ50805.1 - 0.005 16.8 9.0 0.005 16.8 6.2 3.5 3 2 0 3 3 3 1 EamA-like transporter family Kinesin PF00225.18 CBZ50806.1 - 4.9e-33 114.2 0.0 5e-26 91.1 0.0 2.2 2 0 0 2 2 2 2 Kinesin motor domain DUF2205 PF10224.4 CBZ50806.1 - 0.8 9.3 1.5 1.8 8.1 1.0 1.5 1 0 0 1 1 1 0 Predicted coiled-coil protein (DUF2205) SIR2 PF02146.12 CBZ50807.1 - 1.2e-13 51.1 0.1 3.4e-07 30.1 0.0 2.9 1 1 1 2 2 2 2 Sir2 family eIF-3c_N PF05470.7 CBZ50807.1 - 9.8 4.1 5.7 2.9 5.8 0.1 2.5 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus LSM PF01423.17 CBZ50808.1 - 1.6e-16 59.5 1.2 2.1e-16 59.2 0.8 1.1 1 0 0 1 1 1 1 LSM domain LRR_4 PF12799.2 CBZ50808.1 - 0.059 13.0 0.4 0.086 12.4 0.2 1.4 1 0 0 1 1 1 0 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 CBZ50808.1 - 0.059 13.4 0.3 0.2 11.8 0.1 2.0 2 0 0 2 2 2 0 Leucine Rich Repeat Fumerase PF05681.9 CBZ50810.1 - 8.7e-87 290.6 0.0 1.1e-86 290.2 0.0 1.1 1 0 0 1 1 1 1 Fumarate hydratase (Fumerase) Fumerase_C PF05683.7 CBZ50810.1 - 9e-78 260.1 0.0 1.3e-77 259.5 0.0 1.3 1 0 0 1 1 1 1 Fumarase C-terminus B1 PF02246.10 CBZ50810.1 - 0.082 12.7 0.2 0.24 11.2 0.1 1.7 1 0 0 1 1 1 0 Protein L b1 domain IncA PF04156.9 CBZ50811.1 - 0.0051 16.4 21.2 0.0051 16.4 14.7 5.4 2 1 3 5 5 5 1 IncA protein Rota_NSP4 PF01452.11 CBZ50811.1 - 0.062 12.6 5.5 0.13 11.6 3.5 1.7 1 1 0 1 1 1 0 Rotavirus non structural protein PLAC9 PF15205.1 CBZ50811.1 - 0.73 10.1 5.8 16 5.8 0.1 3.3 3 0 0 3 3 3 0 Placenta-specific protein 9 COPI_assoc PF08507.5 CBZ50812.1 - 1.8e-16 60.0 4.1 2.4e-16 59.6 2.9 1.1 1 0 0 1 1 1 1 COPI associated protein PRA1 PF03208.14 CBZ50812.1 - 0.079 12.2 2.7 0.13 11.5 1.9 1.4 1 0 0 1 1 1 0 PRA1 family protein DUF443 PF04276.7 CBZ50812.1 - 0.11 11.9 4.8 0.15 11.4 3.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF443) Cg6151-P PF10233.4 CBZ50812.1 - 0.46 10.4 9.1 0.67 9.9 6.3 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein CG6151-P Claudin_2 PF13903.1 CBZ50812.1 - 0.66 9.6 7.5 0.14 11.8 2.3 1.7 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction Nramp PF01566.13 CBZ50814.1 - 2.3e-90 302.9 15.8 2.3e-90 302.9 10.9 1.5 2 0 0 2 2 2 1 Natural resistance-associated macrophage protein SAG PF04092.8 CBZ50815.1 - 1.3e-42 145.0 35.9 5.3e-28 97.9 6.1 2.1 2 0 0 2 2 2 2 SRS domain SAG PF04092.8 CBZ50816.1 - 1.4e-41 141.7 25.6 1.5e-26 93.1 3.0 2.1 2 0 0 2 2 2 2 SRS domain SAG PF04092.8 CBZ50817.1 - 1.1e-42 145.2 28.7 1.1e-27 96.8 5.0 2.1 2 0 0 2 2 2 2 SRS domain SAG PF04092.8 CBZ50818.1 - 1.2e-42 145.2 29.5 1.1e-27 96.8 6.8 2.1 2 0 0 2 2 2 2 SRS domain SAG PF04092.8 CBZ50819.1 - 1.2e-41 142.0 24.3 1.4e-26 93.3 2.1 2.1 2 0 0 2 2 2 2 SRS domain CAMSAP_CKK PF08683.6 CBZ50819.1 - 0.072 12.7 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 Microtubule-binding calmodulin-regulated spectrin-associated SAG PF04092.8 CBZ50820.1 - 1.3e-40 138.5 27.4 6.1e-27 94.4 5.1 2.2 2 0 0 2 2 2 2 SRS domain SAG PF04092.8 CBZ50821.1 - 2e-40 138.0 26.0 8.5e-27 93.9 6.4 2.1 2 0 0 2 2 2 2 SRS domain SAG PF04092.8 CBZ50822.1 - 1.3e-39 135.4 26.3 8.6e-27 93.9 6.4 2.1 2 0 0 2 2 2 2 SRS domain PP2C PF00481.16 CBZ50824.1 - 2.3e-66 223.7 0.0 1.5e-54 185.1 0.0 3.2 3 0 0 3 3 3 3 Protein phosphatase 2C PP2C_2 PF13672.1 CBZ50824.1 - 0.00012 21.5 0.0 0.016 14.6 0.0 2.5 2 0 0 2 2 2 2 Protein phosphatase 2C GST_C_2 PF13410.1 CBZ50825.1 - 0.0017 18.2 0.8 0.0069 16.2 0.2 2.2 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain Tom37_C PF11801.3 CBZ50825.1 - 0.0022 17.8 0.1 0.11 12.3 0.0 2.5 1 1 0 2 2 2 1 Tom37 C-terminal domain GST_C_3 PF14497.1 CBZ50825.1 - 0.049 14.1 0.0 0.16 12.5 0.0 1.9 2 1 0 2 2 2 0 Glutathione S-transferase, C-terminal domain AAA PF00004.24 CBZ50826.1 - 3.1e-43 147.1 0.0 7e-43 145.9 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 CBZ50826.1 - 5.8e-07 29.7 0.0 0.0012 19.0 0.0 2.6 1 1 1 2 2 2 2 AAA domain AAA_2 PF07724.9 CBZ50826.1 - 1.9e-06 27.9 0.0 5e-06 26.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 CBZ50826.1 - 1.4e-05 24.8 0.1 7.9e-05 22.4 0.1 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 CBZ50826.1 - 2e-05 23.7 0.0 4.2e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus DUF815 PF05673.8 CBZ50826.1 - 4.5e-05 22.5 0.0 7.7e-05 21.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_16 PF13191.1 CBZ50826.1 - 5.9e-05 23.1 0.0 0.00026 21.0 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 CBZ50826.1 - 0.00057 20.7 0.7 0.0017 19.1 0.1 2.2 2 1 0 2 2 1 1 AAA domain AAA_14 PF13173.1 CBZ50826.1 - 0.00074 19.4 0.0 0.0019 18.0 0.0 1.7 2 0 0 2 2 1 1 AAA domain IstB_IS21 PF01695.12 CBZ50826.1 - 0.0008 18.8 0.0 0.0019 17.6 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_19 PF13245.1 CBZ50826.1 - 0.0013 18.3 0.2 0.0028 17.3 0.2 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_18 PF13238.1 CBZ50826.1 - 0.0014 18.9 0.3 0.0066 16.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 CBZ50826.1 - 0.0026 17.6 0.0 0.0065 16.3 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.1 CBZ50826.1 - 0.0035 16.7 0.2 0.061 12.7 0.1 2.2 1 1 1 2 2 2 1 AAA domain AAA_28 PF13521.1 CBZ50826.1 - 0.0044 17.0 1.2 0.0079 16.1 0.0 2.0 3 0 0 3 3 1 1 AAA domain TIP49 PF06068.8 CBZ50826.1 - 0.0053 15.5 0.0 0.01 14.6 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus Zeta_toxin PF06414.7 CBZ50826.1 - 0.0064 15.6 0.0 0.012 14.7 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin Mg_chelatase PF01078.16 CBZ50826.1 - 0.011 14.9 0.0 0.018 14.2 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 CBZ50826.1 - 0.011 15.8 0.0 0.027 14.6 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_24 PF13479.1 CBZ50826.1 - 0.012 15.1 0.2 0.03 13.8 0.1 1.6 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.6 CBZ50826.1 - 0.015 14.8 0.1 0.07 12.7 0.0 2.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.17 CBZ50826.1 - 0.017 13.9 0.0 0.072 11.9 0.0 1.8 2 0 0 2 2 2 0 NB-ARC domain NACHT PF05729.7 CBZ50826.1 - 0.018 14.6 0.0 0.23 11.0 0.0 2.2 1 1 1 2 2 2 0 NACHT domain PhoH PF02562.11 CBZ50826.1 - 0.018 14.2 0.2 0.097 11.8 0.1 2.1 2 0 0 2 2 2 0 PhoH-like protein Arch_ATPase PF01637.13 CBZ50826.1 - 0.037 13.7 0.4 0.42 10.2 0.0 2.5 2 1 0 3 3 3 0 Archaeal ATPase KaiC PF06745.8 CBZ50826.1 - 0.066 12.3 0.2 0.52 9.3 0.0 2.2 1 1 1 2 2 2 0 KaiC NTPase_1 PF03266.10 CBZ50826.1 - 0.067 12.8 0.5 0.57 9.8 0.1 2.6 2 1 0 2 2 2 0 NTPase AAA_11 PF13086.1 CBZ50826.1 - 0.086 12.4 0.1 0.18 11.3 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.1 CBZ50826.1 - 0.11 12.0 0.0 0.26 10.8 0.0 1.6 2 0 0 2 2 1 0 AAA domain Parvo_NS1 PF01057.12 CBZ50826.1 - 0.13 11.1 0.0 0.22 10.3 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 MIP PF00230.15 CBZ50827.1 - 1.1e-13 51.1 35.8 1.1e-07 31.6 8.1 3.0 2 2 0 2 2 2 2 Major intrinsic protein Ribosomal_L14e PF01929.12 CBZ50828.1 - 2.1e-27 95.3 5.9 2.8e-27 94.8 4.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L14 KOW PF00467.24 CBZ50828.1 - 0.0074 15.9 0.0 0.013 15.1 0.0 1.5 1 0 0 1 1 1 1 KOW motif OB_RNB PF08206.6 CBZ50828.1 - 0.039 13.4 0.0 0.075 12.5 0.0 1.5 1 0 0 1 1 1 0 Ribonuclease B OB domain Tmemb_9 PF05434.6 CBZ50828.1 - 0.081 12.6 0.2 0.12 12.1 0.2 1.3 1 0 0 1 1 1 0 TMEM9 Abhydrolase_5 PF12695.2 CBZ50829.1 - 5.2e-15 55.4 0.0 1.1e-14 54.4 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CBZ50829.1 - 2.5e-14 53.7 0.0 6.5e-14 52.3 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CBZ50829.1 - 1.2e-06 28.2 0.2 1.7e-05 24.4 0.1 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 CBZ50829.1 - 4.6e-05 22.7 0.0 0.00011 21.5 0.0 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family BAAT_C PF08840.6 CBZ50829.1 - 0.0001 22.0 0.1 0.00048 19.9 0.1 1.8 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_4 PF08386.5 CBZ50829.1 - 0.00086 19.1 0.0 0.0015 18.4 0.0 1.3 1 0 0 1 1 1 1 TAP-like protein Peptidase_S15 PF02129.13 CBZ50829.1 - 0.0019 17.6 0.0 0.0043 16.5 0.0 1.5 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) FSH1 PF03959.8 CBZ50829.1 - 0.0072 15.7 0.1 0.013 14.9 0.1 1.5 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.11 CBZ50829.1 - 0.049 13.0 0.0 0.16 11.4 0.0 1.8 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase DLH PF01738.13 CBZ50829.1 - 0.06 12.6 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 Dienelactone hydrolase family Ribonuclease_3 PF00636.21 CBZ50831.1 - 8.3e-26 90.6 0.4 5.8e-08 33.1 0.0 4.7 4 0 0 4 4 4 3 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 CBZ50831.1 - 1.4e-12 47.7 0.0 0.014 15.3 0.0 3.9 3 0 0 3 3 3 3 Ribonuclease-III-like DEAD PF00270.24 CBZ50831.1 - 1.3e-11 44.3 0.0 4e-05 23.1 0.0 2.3 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.26 CBZ50831.1 - 4.3e-11 42.5 0.0 1.1e-10 41.1 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Daxx PF03344.10 CBZ50831.1 - 0.00041 18.9 23.7 0.00041 18.9 16.4 10.0 9 2 0 9 9 9 4 Daxx Family ResIII PF04851.10 CBZ50831.1 - 0.0018 18.1 0.0 0.002 17.9 0.0 5.4 6 0 0 6 6 6 2 Type III restriction enzyme, res subunit TPR_16 PF13432.1 CBZ50832.1 - 8e-06 26.3 0.5 8e-06 26.3 0.3 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.1 CBZ50832.1 - 6.8e-05 22.4 0.3 0.00018 21.0 0.0 1.9 2 0 0 2 2 2 1 TPR repeat TPR_7 PF13176.1 CBZ50832.1 - 0.03 14.1 0.0 0.089 12.6 0.0 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat FAM176 PF14851.1 CBZ50832.1 - 0.041 13.5 1.4 0.099 12.3 0.9 1.5 1 0 0 1 1 1 0 FAM176 family TPR_12 PF13424.1 CBZ50832.1 - 0.042 13.7 0.5 0.18 11.7 0.1 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat PDZ_2 PF13180.1 CBZ50832.1 - 0.068 13.0 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 PDZ domain PDZ PF00595.19 CBZ50832.1 - 0.083 13.0 0.0 0.17 12.0 0.0 1.4 1 0 0 1 1 1 0 PDZ domain (Also known as DHR or GLGF) TPR_2 PF07719.12 CBZ50832.1 - 0.085 12.8 0.1 0.28 11.1 0.0 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_1 PF00515.23 CBZ50832.1 - 0.094 12.3 0.0 0.23 11.1 0.0 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat MIP-T3 PF10243.4 CBZ50832.1 - 0.34 9.3 10.0 0.54 8.6 6.9 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Adaptin_N PF01602.15 CBZ50833.1 - 1.4e-79 267.8 3.7 2.3e-79 267.1 2.6 1.2 1 0 0 1 1 1 1 Adaptin N terminal region Coatomer_b_Cpla PF14806.1 CBZ50833.1 - 2.1e-46 156.8 0.1 7.4e-22 77.4 0.0 2.7 2 0 0 2 2 2 2 Coatomer beta subunit appendage platform Coatamer_beta_C PF07718.7 CBZ50833.1 - 1.6e-37 128.3 0.0 3.8e-37 127.0 0.0 1.6 1 0 0 1 1 1 1 Coatomer beta C-terminal region HEAT_2 PF13646.1 CBZ50833.1 - 6.2e-11 42.4 5.5 1e-07 32.1 0.0 4.4 3 1 0 3 3 3 2 HEAT repeats HEAT PF02985.17 CBZ50833.1 - 0.0013 18.6 0.1 0.071 13.2 0.0 3.7 3 0 0 3 3 3 1 HEAT repeat Cnd1 PF12717.2 CBZ50833.1 - 0.0047 16.7 0.5 0.0047 16.7 0.3 3.3 3 1 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.1 CBZ50833.1 - 0.0048 17.3 3.3 13 6.3 0.0 5.9 6 1 0 6 6 6 1 HEAT-like repeat DUF2435 PF10363.4 CBZ50833.1 - 0.016 15.1 1.5 0.83 9.5 0.0 3.7 3 1 0 3 3 3 0 Protein of unknown function (DUF2435) Arm PF00514.18 CBZ50833.1 - 0.063 13.1 5.5 10 6.1 0.1 5.0 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat Dynamin_N PF00350.18 CBZ50833.1 - 0.072 12.9 0.0 0.24 11.2 0.0 1.8 2 0 0 2 2 2 0 Dynamin family STN PF07660.9 CBZ50833.1 - 0.083 12.4 0.1 0.68 9.5 0.1 2.3 2 0 0 2 2 2 0 Secretin and TonB N terminus short domain ubiquitin PF00240.18 CBZ50834.1 - 3e-06 26.5 0.1 1.4e-05 24.3 0.1 2.2 2 0 0 2 2 2 1 Ubiquitin family Tubulin PF00091.20 CBZ50835.1 - 1.8e-70 237.1 0.0 3e-70 236.4 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 CBZ50835.1 - 1e-48 164.5 0.2 1.5e-48 163.9 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 CBZ50835.1 - 0.00033 20.6 0.0 0.00082 19.4 0.0 1.7 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.1 CBZ50835.1 - 0.0075 15.7 0.0 0.014 14.8 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain Pkinase PF00069.20 CBZ50836.1 - 1e-38 133.0 0.0 1.9e-37 128.8 0.0 2.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ50836.1 - 3.6e-16 59.0 0.0 5.7e-16 58.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBZ50836.1 - 3.2e-05 23.0 0.0 5.3e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like zf-DHHC PF01529.15 CBZ50837.1 - 5.3e-30 104.0 14.3 2.1e-29 102.1 8.1 2.6 2 1 0 2 2 2 1 DHHC palmitoyltransferase Tfb4 PF03850.9 CBZ50838.1 - 2.7e-30 105.5 6.0 4e-30 105.0 3.1 2.0 3 0 0 3 3 3 1 Transcription factor Tfb4 SUFU_C PF12470.3 CBZ50838.1 - 0.17 11.4 0.0 0.35 10.4 0.0 1.4 1 0 0 1 1 1 0 Suppressor of Fused Gli/Ci N terminal binding domain PDEase_I PF00233.14 CBZ50839.1 - 1.8e-26 93.3 2.7 8.2e-25 87.9 0.1 2.2 2 0 0 2 2 2 2 3'5'-cyclic nucleotide phosphodiesterase Pkinase PF00069.20 CBZ50840.1 - 1e-43 149.3 0.0 1.2e-43 149.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ50840.1 - 1.8e-21 76.3 0.0 2.2e-21 76.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBZ50840.1 - 4.4e-07 29.1 0.0 0.0014 17.6 0.0 2.2 1 1 1 2 2 2 2 Kinase-like Kdo PF06293.9 CBZ50840.1 - 3.3e-05 23.0 0.1 5.6e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CBZ50840.1 - 0.013 15.2 0.0 0.025 14.2 0.0 1.6 2 0 0 2 2 2 0 Phosphotransferase enzyme family Cyclin PF08613.6 CBZ50841.1 - 4.8e-10 40.0 0.0 7.1e-10 39.4 0.0 1.3 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 CBZ50841.1 - 1.9e-09 37.1 0.0 2.6e-09 36.7 0.0 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain DUF1768 PF08719.6 CBZ50842.1 - 8.4e-10 38.6 0.0 3.5e-09 36.5 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF1768) Ecl1 PF12855.2 CBZ50842.1 - 0.078 12.2 1.9 0.31 10.3 1.3 2.1 1 0 0 1 1 1 0 Life-span regulatory factor Dus PF01207.12 CBZ50843.1 - 1.1e-23 83.5 0.0 1.7e-11 43.5 0.0 3.9 1 1 1 2 2 2 2 Dihydrouridine synthase (Dus) MFS_1 PF07690.11 CBZ50843.1 - 0.0002 20.2 5.3 0.00031 19.5 3.7 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF2102 PF09875.4 CBZ50843.1 - 0.027 13.9 0.0 0.054 13.0 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2102) BTB PF00651.26 CBZ50844.1 - 1.3e-19 70.1 0.1 6.8e-19 67.9 0.0 2.0 2 0 0 2 2 2 1 BTB/POZ domain Skp1_POZ PF03931.10 CBZ50844.1 - 0.00033 20.7 0.0 0.0008 19.4 0.0 1.6 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain Methyltransf_23 PF13489.1 CBZ50845.1 - 6.3e-19 68.2 0.0 8.6e-19 67.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CBZ50845.1 - 9.5e-12 45.4 0.0 1.6e-11 44.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CBZ50845.1 - 5.1e-11 42.3 0.0 7.5e-10 38.5 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CBZ50845.1 - 1.2e-10 41.7 0.1 5.7e-10 39.5 0.1 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CBZ50845.1 - 4.7e-10 39.8 0.0 1.1e-09 38.6 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 CBZ50845.1 - 6.7e-07 29.3 0.4 1.4e-06 28.3 0.3 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CBZ50845.1 - 4.7e-06 26.9 0.0 8.8e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 CBZ50845.1 - 0.00015 20.9 0.0 0.047 12.7 0.1 2.1 2 0 0 2 2 2 2 Mycolic acid cyclopropane synthetase MTS PF05175.9 CBZ50845.1 - 0.00031 20.1 0.9 0.0021 17.4 0.6 2.0 1 1 0 1 1 1 1 Methyltransferase small domain TPMT PF05724.6 CBZ50845.1 - 0.00061 19.2 0.0 0.00095 18.6 0.0 1.2 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) PrmA PF06325.8 CBZ50845.1 - 0.00068 18.8 0.7 0.0013 17.9 0.5 1.5 1 1 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) NodS PF05401.6 CBZ50845.1 - 0.0061 15.9 0.0 0.64 9.3 0.0 2.1 2 0 0 2 2 2 1 Nodulation protein S (NodS) Methyltransf_32 PF13679.1 CBZ50845.1 - 0.038 13.6 0.0 0.065 12.9 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase domain MetW PF07021.7 CBZ50845.1 - 0.049 13.0 0.1 0.11 11.8 0.0 1.6 1 1 1 2 2 2 0 Methionine biosynthesis protein MetW PCMT PF01135.14 CBZ50845.1 - 0.17 11.4 0.1 0.27 10.7 0.1 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Sec7 PF01369.15 CBZ50847.1 - 5.8e-40 137.0 0.0 8.7e-40 136.4 0.0 1.2 1 0 0 1 1 1 1 Sec7 domain RabGAP-TBC PF00566.13 CBZ50847.1 - 1.1e-30 106.6 0.2 2e-30 105.8 0.1 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain MCLC PF05934.6 CBZ50847.1 - 0.95 7.6 0.0 2 6.6 0.0 1.4 1 0 0 1 1 1 0 Mid-1-related chloride channel (MCLC) VIT1 PF01988.14 CBZ50849.1 - 1.1e-62 211.3 2.1 1.3e-62 211.0 1.5 1.1 1 0 0 1 1 1 1 VIT family DUF2453 PF10507.4 CBZ50849.1 - 0.0094 15.7 1.2 0.0094 15.7 0.8 1.9 2 1 0 2 2 2 1 Protein of unknown function (DUF2453) DUF2532 PF10811.3 CBZ50849.1 - 0.12 12.2 0.1 0.17 11.6 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2532) Pkinase_Tyr PF07714.12 CBZ50851.1 - 1.9e-10 40.2 0.0 4.1e-05 22.7 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.20 CBZ50851.1 - 4.8e-09 35.7 0.0 1.6e-08 34.0 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain CPW_WPC PF09717.5 CBZ50852.1 - 2.3e-66 220.2 37.1 7.8e-15 55.2 1.0 5.2 5 0 0 5 5 5 5 Plasmodium falciparum domain of unknown function (CPW_WPC) Iso_dh PF00180.15 CBZ50853.1 - 1.2e-69 234.9 0.0 1.3e-69 234.7 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase UAA PF08449.6 CBZ50854.1 - 8.8e-08 31.4 3.0 9.2e-08 31.3 1.5 1.3 1 1 0 1 1 1 1 UAA transporter family Nuc_sug_transp PF04142.10 CBZ50854.1 - 3.5e-07 29.5 3.9 1.5e-06 27.5 2.7 1.9 1 1 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.15 CBZ50854.1 - 2e-05 24.5 3.4 2e-05 24.5 2.4 3.1 1 1 2 3 3 3 1 EamA-like transporter family TPT PF03151.11 CBZ50854.1 - 0.0012 18.5 12.6 0.013 15.1 2.5 2.5 2 0 0 2 2 2 2 Triose-phosphate Transporter family UPF0546 PF10639.4 CBZ50854.1 - 0.0036 17.1 0.4 0.0098 15.7 0.1 1.8 2 0 0 2 2 2 1 Uncharacterised protein family UPF0546 DUF4418 PF14387.1 CBZ50854.1 - 0.016 14.9 2.2 0.016 14.9 1.5 2.3 3 1 0 3 3 3 0 Domain of unknown function (DUF4418) EmrE PF13536.1 CBZ50854.1 - 4 7.6 21.1 0.33 11.1 6.6 3.4 2 1 0 2 2 2 0 Multidrug resistance efflux transporter DUF1129 PF06570.6 CBZ50854.1 - 4.4 6.5 8.0 0.18 11.1 0.7 2.2 2 1 1 3 3 3 0 Protein of unknown function (DUF1129) RRM_1 PF00076.17 CBZ50855.1 - 2.3e-26 91.2 0.0 5.3e-08 32.3 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBZ50855.1 - 1.7e-19 69.5 0.2 3.1e-06 27.0 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBZ50855.1 - 2.1e-19 69.0 0.0 1.2e-06 28.2 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 CBZ50855.1 - 2.9e-06 26.9 0.0 0.00075 19.2 0.0 3.1 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif Limkain-b1 PF11608.3 CBZ50855.1 - 0.00023 20.8 0.2 0.11 12.2 0.0 2.9 3 0 0 3 3 3 2 Limkain b1 DUF1537 PF07005.6 CBZ50855.1 - 0.033 13.8 0.1 0.069 12.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF1537 tRNA-synt_1 PF00133.17 CBZ50856.1 - 3.5e-28 97.9 0.2 8.4e-12 43.8 0.0 4.8 4 1 1 5 5 5 4 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.6 CBZ50856.1 - 9.8e-22 77.1 0.0 4.8e-07 28.7 0.0 3.9 3 1 1 4 4 4 4 tRNA synthetases class I (M) Anticodon_1 PF08264.8 CBZ50856.1 - 9.1e-11 41.7 0.0 5.4e-10 39.2 0.0 2.1 1 1 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1_2 PF13603.1 CBZ50856.1 - 1.2e-10 41.0 0.0 4.4e-10 39.1 0.0 1.8 1 1 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1f PF01921.13 CBZ50856.1 - 0.0072 15.0 0.0 0.014 14.0 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (K) tRNA-synt_1e PF01406.14 CBZ50856.1 - 0.067 12.3 0.0 0.39 9.7 0.0 1.9 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain Pkinase PF00069.20 CBZ50858.1 - 6.8e-58 195.8 0.0 4.8e-57 193.0 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ50858.1 - 3.8e-33 114.6 0.0 4.9e-33 114.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBZ50858.1 - 6.9e-11 41.6 0.0 3.3e-10 39.4 0.0 1.9 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 CBZ50858.1 - 0.0025 17.6 0.1 0.059 13.0 0.1 2.4 2 1 0 2 2 2 1 Phosphotransferase enzyme family RNA_pol_Rpc4 PF05132.9 CBZ50861.1 - 3.1e-14 53.0 0.1 2.8e-12 46.7 0.0 3.3 1 1 0 1 1 1 1 RNA polymerase III RPC4 Mad3_BUB1_I PF08311.7 CBZ50863.1 - 0.13 12.0 4.3 0.058 13.1 0.4 2.4 2 1 1 3 3 3 0 Mad3/BUB1 homology region 1 Synaptobrevin PF00957.16 CBZ50863.1 - 0.52 9.9 16.8 2.8 7.5 0.2 4.9 3 1 1 4 4 4 0 Synaptobrevin Baculo_PEP_C PF04513.7 CBZ50863.1 - 0.56 10.0 23.1 0.025 14.3 1.2 5.2 3 2 2 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus T2SF PF00482.18 CBZ50863.1 - 1.2 9.1 8.1 16 5.4 0.1 4.0 4 1 0 4 4 4 0 Type II secretion system (T2SS), protein F MCPsignal PF00015.16 CBZ50863.1 - 3.1 7.2 36.8 2.5 7.5 6.4 5.2 2 2 4 6 6 6 0 Methyl-accepting chemotaxis protein (MCP) signalling domain AMP-binding PF00501.23 CBZ50865.1 - 7.7e-94 314.4 0.0 9.3e-94 314.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 CBZ50865.1 - 3.1e-21 76.0 0.7 7.9e-21 74.7 0.3 1.9 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Ank_4 PF13637.1 CBZ50866.1 - 0.0028 18.1 0.0 0.026 15.0 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 CBZ50866.1 - 0.0037 17.5 0.0 0.0089 16.3 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 CBZ50866.1 - 0.012 15.8 0.0 0.09 13.0 0.0 2.2 2 0 0 2 2 2 0 Ankyrin repeats (many copies) DUF3452 PF11934.3 CBZ50866.1 - 0.04 13.2 0.0 0.1 11.8 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3452) Mfp-3 PF04202.8 CBZ50866.1 - 0.044 13.9 0.0 0.12 12.5 0.0 1.7 1 0 0 1 1 1 0 Foot protein 3 Menin PF05053.8 CBZ50866.1 - 0.27 9.3 0.1 0.4 8.7 0.0 1.2 1 0 0 1 1 1 0 Menin Thioredoxin PF00085.15 CBZ50867.1 - 4.2e-15 55.2 0.0 6.2e-15 54.7 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 CBZ50867.1 - 9.8e-05 22.3 0.1 0.0039 17.2 0.1 2.8 2 1 0 2 2 2 1 Thioredoxin-like Thioredoxin_7 PF13899.1 CBZ50867.1 - 0.0036 17.2 0.1 0.0067 16.4 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like LSR PF05624.9 CBZ50867.1 - 0.2 11.4 3.2 4.4 7.1 0.4 2.6 2 0 0 2 2 2 0 Lipolysis stimulated receptor (LSR) PBP1_TM PF14812.1 CBZ50868.1 - 0.023 14.9 7.9 0.034 14.4 5.5 1.2 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Sporozoite_P67 PF05642.6 CBZ50868.1 - 0.26 9.0 1.8 0.24 9.2 1.3 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF2457 PF10446.4 CBZ50868.1 - 0.84 8.2 11.2 0.82 8.3 7.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) CAF1A PF12253.3 CBZ50868.1 - 0.97 9.5 9.4 1.4 9.1 6.5 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 subunit A Kazal_1 PF00050.16 CBZ50869.1 - 7.8e-20 70.6 9.8 1.8e-09 37.4 3.0 2.8 1 1 1 2 2 2 2 Kazal-type serine protease inhibitor domain Kazal_2 PF07648.10 CBZ50869.1 - 1.1e-16 60.4 12.9 4.2e-09 36.1 1.2 3.3 3 2 0 3 3 3 2 Kazal-type serine protease inhibitor domain OTU PF02338.14 CBZ50870.1 - 3e-06 27.8 0.0 7.3e-06 26.5 0.0 1.6 2 0 0 2 2 2 1 OTU-like cysteine protease Elf1 PF05129.8 CBZ50872.1 - 0.096 12.3 8.4 0.46 10.2 5.8 2.1 1 1 0 1 1 1 0 Transcription elongation factor Elf1 like Rad60-SLD PF11976.3 CBZ50873.1 - 4.5e-25 87.1 0.1 5.3e-25 86.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 CBZ50873.1 - 8.5e-09 34.6 0.0 1.1e-08 34.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin family UBX PF00789.15 CBZ50873.1 - 0.013 15.5 0.0 0.014 15.4 0.0 1.2 1 0 0 1 1 1 0 UBX domain HJURP_C PF12347.3 CBZ50873.1 - 0.079 12.5 0.2 0.13 11.8 0.2 1.4 1 0 0 1 1 1 0 Holliday junction regulator protein family C-terminal repeat Lysine_decarbox PF03641.9 CBZ50874.1 - 6.7e-25 87.4 0.0 1e-24 86.8 0.0 1.3 1 0 0 1 1 1 1 Possible lysine decarboxylase Fib_alpha PF08702.5 CBZ50876.1 - 0.29 11.2 14.6 0.23 11.5 1.8 2.3 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family APG6 PF04111.7 CBZ50876.1 - 0.5 9.3 29.6 0.014 14.4 4.6 2.2 2 0 0 2 2 2 0 Autophagy protein Apg6 BLOC1_2 PF10046.4 CBZ50876.1 - 0.63 10.2 14.5 3.1 7.9 1.4 3.0 1 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Tropomyosin_1 PF12718.2 CBZ50876.1 - 0.64 9.8 40.6 0.75 9.6 5.6 3.4 2 1 1 3 3 3 0 Tropomyosin like Herpes_UL87 PF03043.9 CBZ50876.1 - 3.9 5.7 7.8 5.9 5.1 5.4 1.2 1 0 0 1 1 1 0 Herpesvirus UL87 family PUF PF00806.14 CBZ50877.1 - 1.5e-08 33.6 0.0 0.23 11.0 0.0 6.1 7 0 0 7 7 7 3 Pumilio-family RNA binding repeat Aldolase PF01081.14 CBZ50877.1 - 0.16 11.1 0.0 2.8 7.0 0.0 2.2 2 0 0 2 2 2 0 KDPG and KHG aldolase DNA_mis_repair PF01119.14 CBZ50878.1 - 1.2e-20 73.1 0.0 2.2e-20 72.2 0.0 1.4 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.1 CBZ50878.1 - 9.8e-10 38.2 1.5 1.6e-09 37.5 0.0 2.1 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 CBZ50878.1 - 1.3e-09 37.7 0.0 2.7e-09 36.7 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Pex19 PF04614.7 CBZ50879.1 - 1.1e-05 25.2 14.2 0.0068 16.0 0.0 4.5 4 1 0 4 4 4 2 Pex19 protein family Apt1 PF10351.4 CBZ50880.1 - 1.7 7.4 6.4 3.2 6.5 4.4 1.4 1 0 0 1 1 1 0 Golgi-body localisation protein domain BT1 PF03092.11 CBZ50881.1 - 1.6e-73 247.9 13.2 2.2e-73 247.4 9.1 1.1 1 0 0 1 1 1 1 BT1 family DUF605 PF04652.11 CBZ50884.1 - 2 7.7 15.8 2.7 7.3 10.9 1.2 1 0 0 1 1 1 0 Vta1 like Gly_transf_sug PF04488.10 CBZ50885.1 - 2.8e-06 27.6 0.0 6e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.2 CBZ50885.1 - 0.13 10.7 0.0 0.18 10.2 0.0 1.1 1 0 0 1 1 1 0 TcdA/TcdB catalytic glycosyltransferase domain Caps_synth PF05704.7 CBZ50885.1 - 0.44 9.6 0.0 0.7 9.0 0.0 1.2 1 0 0 1 1 1 0 Capsular polysaccharide synthesis protein GNT-I PF03071.10 CBZ50886.1 - 4.5e-10 38.6 0.0 4.9e-08 31.9 0.0 2.8 2 1 0 2 2 2 2 GNT-I family Cas_CT1975 PF09344.5 CBZ50887.1 - 0.0012 18.2 0.9 0.0021 17.5 0.2 1.6 1 1 0 1 1 1 1 CT1975-like protein PapC_N PF13954.1 CBZ50887.1 - 0.026 14.0 2.1 0.052 13.1 1.4 1.5 1 1 0 1 1 1 0 PapC N-terminal domain PRP3 PF08572.5 CBZ50887.1 - 0.62 9.4 11.0 0.19 11.0 1.8 2.1 2 0 0 2 2 2 0 pre-mRNA processing factor 3 (PRP3) Vfa1 PF08432.5 CBZ50887.1 - 4.5 7.2 13.7 8.7 6.3 3.5 2.2 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 DUF3664 PF12406.3 CBZ50887.1 - 6.7 7.3 16.4 0.13 12.9 5.1 2.2 2 0 0 2 2 2 0 Surface protein Adaptin_N PF01602.15 CBZ50888.1 - 1.6e-83 280.8 0.2 2.1e-83 280.4 0.1 1.0 1 0 0 1 1 1 1 Adaptin N terminal region HEAT_2 PF13646.1 CBZ50888.1 - 1.3e-05 25.4 11.8 0.027 14.7 0.1 5.2 4 2 2 6 6 6 3 HEAT repeats B2-adapt-app_C PF09066.5 CBZ50888.1 - 4.2e-05 23.3 0.0 0.00018 21.3 0.0 2.0 1 1 0 1 1 1 1 Beta2-adaptin appendage, C-terminal sub-domain HEAT PF02985.17 CBZ50888.1 - 0.00077 19.3 7.8 1.2 9.4 0.0 5.1 5 0 0 5 5 5 2 HEAT repeat Cnd1 PF12717.2 CBZ50888.1 - 0.0043 16.9 0.6 0.15 11.8 0.0 3.5 2 2 2 4 4 4 1 non-SMC mitotic condensation complex subunit 1 DUF4355 PF14265.1 CBZ50888.1 - 0.32 10.9 7.5 17 5.4 3.3 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4355) HEAT_EZ PF13513.1 CBZ50888.1 - 0.34 11.4 6.4 2.6 8.6 0.2 5.1 4 2 3 7 7 7 0 HEAT-like repeat Pantoate_ligase PF02569.10 CBZ50889.1 - 2.6e-51 174.0 0.0 2.4e-26 92.1 0.0 2.1 2 0 0 2 2 2 2 Pantoate-beta-alanine ligase CN_hydrolase PF00795.17 CBZ50890.1 - 2.3e-20 72.7 0.0 4e-20 71.9 0.0 1.4 1 1 0 1 1 1 1 Carbon-nitrogen hydrolase RNase_Zc3h12a PF11977.3 CBZ50891.1 - 6.6e-28 97.4 0.0 1.3e-27 96.5 0.0 1.4 1 0 0 1 1 1 1 Zc3h12a-like Ribonuclease NYN domain EST1_DNA_bind PF10373.4 CBZ50891.1 - 2.1e-06 27.1 0.0 4.9e-06 25.9 0.0 1.6 1 0 0 1 1 1 1 Est1 DNA/RNA binding domain PhoD PF09423.5 CBZ50893.1 - 4.4e-14 51.9 0.1 4e-13 48.7 0.0 2.2 2 1 1 3 3 3 1 PhoD-like phosphatase DUF788 PF05620.6 CBZ50893.1 - 0.083 12.7 0.0 0.2 11.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF788) Las1 PF04031.8 CBZ50894.1 - 1.6e-28 99.3 0.0 3.4e-28 98.2 0.0 1.6 1 0 0 1 1 1 1 Las1-like Methyltransf_11 PF08241.7 CBZ50895.1 - 9.5e-06 26.0 0.0 0.045 14.2 0.0 2.6 2 0 0 2 2 2 2 Methyltransferase domain TrbC PF04956.8 CBZ50896.1 - 9.2 6.3 8.7 0.35 10.8 1.0 2.2 2 0 0 2 2 2 0 TrbC/VIRB2 family Peptidase_M14 PF00246.19 CBZ50897.1 - 2.4e-19 70.0 0.0 4.4e-19 69.1 0.0 1.3 1 0 0 1 1 1 1 Zinc carboxypeptidase AstE_AspA PF04952.9 CBZ50897.1 - 0.0013 17.7 0.0 0.002 17.0 0.0 1.2 1 0 0 1 1 1 1 Succinylglutamate desuccinylase / Aspartoacylase family PP2C PF00481.16 CBZ50899.1 - 4.7e-31 108.1 0.1 1e-19 70.9 0.0 4.1 4 0 0 4 4 4 4 Protein phosphatase 2C RRM_1 PF00076.17 CBZ50900.1 - 1.7e-30 104.4 2.3 3e-16 58.8 0.1 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBZ50900.1 - 2.2e-30 104.4 0.8 7.4e-14 51.4 0.1 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBZ50900.1 - 1.4e-10 40.8 1.4 0.0002 21.1 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 CBZ50900.1 - 7.4e-06 25.7 1.3 0.021 14.6 0.1 2.5 1 1 1 2 2 2 2 RNA binding motif Nup35_RRM_2 PF14605.1 CBZ50900.1 - 0.16 11.8 0.2 2.9 7.7 0.0 2.3 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif DUF1510 PF07423.6 CBZ50900.1 - 2.6 7.3 7.7 4.1 6.7 5.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) zf-ribbon_3 PF13248.1 CBZ50902.1 - 0.00077 18.5 4.8 0.0016 17.6 3.4 1.5 1 0 0 1 1 1 1 zinc-ribbon domain DZR PF12773.2 CBZ50902.1 - 0.0022 17.7 1.0 0.004 16.9 0.7 1.4 1 0 0 1 1 1 1 Double zinc ribbon Glutaredoxin PF00462.19 CBZ50902.1 - 3 7.8 5.7 27 4.8 0.0 4.1 3 1 0 3 3 3 0 Glutaredoxin Voltage_CLC PF00654.15 CBZ50903.1 - 1.9e-63 214.6 24.4 4.7e-23 81.7 6.9 3.2 3 0 0 3 3 3 3 Voltage gated chloride channel CBS PF00571.23 CBZ50903.1 - 4.5e-08 32.7 0.1 0.0081 15.9 0.1 2.7 2 0 0 2 2 2 2 CBS domain Dak2 PF02734.12 CBZ50906.1 - 0.01 15.4 0.7 0.017 14.7 0.5 1.4 1 0 0 1 1 1 0 DAK2 domain CENP-F_leu_zip PF10473.4 CBZ50906.1 - 0.045 13.6 26.8 0.44 10.3 4.7 2.4 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF972 PF06156.8 CBZ50906.1 - 0.065 13.5 22.8 0.043 14.1 3.2 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF972) PHA_synth_III_E PF09712.5 CBZ50906.1 - 0.15 11.4 9.1 0.24 10.7 6.3 1.3 1 1 0 1 1 1 0 Poly(R)-hydroxyalkanoic acid synthase subunit (PHA_synth_III_E) Filament PF00038.16 CBZ50906.1 - 0.32 10.4 25.1 0.25 10.7 6.2 2.6 1 1 2 3 3 3 0 Intermediate filament protein T2SG PF08334.6 CBZ50906.1 - 0.39 10.5 3.6 0.17 11.6 0.6 1.9 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein G RNA_pol_Rpb1_7 PF04990.7 CBZ50906.1 - 0.44 10.2 6.5 0.096 12.4 0.9 2.0 2 0 0 2 2 2 0 RNA polymerase Rpb1, domain 7 DUF1492 PF07374.6 CBZ50906.1 - 0.46 10.6 5.5 0.58 10.2 0.1 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1492) DUF4239 PF14023.1 CBZ50906.1 - 0.52 9.6 5.2 5.3 6.3 3.6 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF4239) Reo_sigmaC PF04582.7 CBZ50906.1 - 0.67 9.0 4.1 7.9 5.5 0.2 2.3 1 1 0 2 2 2 0 Reovirus sigma C capsid protein Microtub_assoc PF07989.6 CBZ50906.1 - 1.5 8.6 20.2 1.5 8.6 0.4 3.6 3 1 0 3 3 3 0 Microtubule associated DUF4446 PF14584.1 CBZ50906.1 - 1.7 8.4 10.0 0.26 11.1 0.5 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF4446) Synaptobrevin PF00957.16 CBZ50906.1 - 3.6 7.2 10.5 0.65 9.6 2.9 2.2 2 0 0 2 2 2 0 Synaptobrevin Hexokinase_1 PF00349.16 CBZ50907.1 - 9.7e-55 185.0 0.0 1.4e-54 184.5 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_2 PF03727.11 CBZ50907.1 - 2.4e-49 167.7 0.3 3.6e-49 167.1 0.2 1.3 1 0 0 1 1 1 1 Hexokinase PPP4R2 PF09184.6 CBZ50908.1 - 7.8e-09 35.4 0.0 7.8e-09 35.4 0.0 3.7 4 1 0 4 4 4 2 PPP4R2 DUF4600 PF15372.1 CBZ50910.1 - 0.0043 17.2 3.0 0.015 15.5 1.2 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4600) IncA PF04156.9 CBZ50910.1 - 0.14 11.7 4.1 0.05 13.1 1.1 1.5 2 0 0 2 2 2 0 IncA protein zf-C4H2 PF10146.4 CBZ50910.1 - 0.4 10.6 2.8 0.57 10.1 1.9 1.4 1 1 0 1 1 1 0 Zinc finger-containing protein PAH PF02671.16 CBZ50910.1 - 0.71 9.5 3.8 0.35 10.5 0.6 2.0 2 0 0 2 2 2 0 Paired amphipathic helix repeat DivIC PF04977.10 CBZ50910.1 - 1.9 7.9 4.9 0.73 9.3 0.9 1.9 2 0 0 2 2 2 0 Septum formation initiator TMF_DNA_bd PF12329.3 CBZ50910.1 - 2.4 8.0 10.1 10 6.0 0.1 2.5 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding WD40 PF00400.27 CBZ50911.1 - 4.5e-42 140.4 7.4 1.1e-09 37.7 0.0 6.5 6 0 0 6 6 6 5 WD domain, G-beta repeat eIF2A PF08662.6 CBZ50911.1 - 1.9e-06 27.7 0.3 0.29 10.8 0.0 3.4 3 1 0 4 4 4 2 Eukaryotic translation initiation factor eIF2A PQQ_2 PF13360.1 CBZ50911.1 - 0.002 17.6 0.5 0.015 14.7 0.3 2.2 1 1 0 1 1 1 1 PQQ-like domain Nup160 PF11715.3 CBZ50911.1 - 5 5.1 6.5 0.71 7.9 0.3 2.3 2 1 0 2 2 2 0 Nucleoporin Nup120/160 CLTH PF10607.4 CBZ50913.1 - 3.2e-17 62.5 0.0 5.1e-17 61.9 0.0 1.3 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_UBOX PF13445.1 CBZ50913.1 - 0.0005 19.7 0.0 0.0014 18.2 0.0 1.8 1 0 0 1 1 1 1 RING-type zinc-finger Rtf2 PF04641.7 CBZ50913.1 - 0.074 12.2 0.0 0.15 11.2 0.0 1.4 1 0 0 1 1 1 0 Rtf2 RING-finger Latarcin PF10279.4 CBZ50913.1 - 0.15 12.2 0.0 0.37 11.0 0.0 1.6 1 1 0 1 1 1 0 Latarcin precursor TPR_11 PF13414.1 CBZ50914.1 - 1.3e-18 66.4 0.7 5.5e-16 57.9 0.1 2.6 1 1 1 2 2 2 2 TPR repeat U-box PF04564.10 CBZ50914.1 - 3.3e-16 59.0 0.0 1.4e-14 53.7 0.0 2.4 1 1 0 1 1 1 1 U-box domain TPR_1 PF00515.23 CBZ50914.1 - 5.6e-12 44.7 1.1 8e-06 25.2 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.1 CBZ50914.1 - 5.5e-06 26.1 0.2 0.3 11.3 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 CBZ50914.1 - 3.3e-05 23.4 7.0 0.0028 17.4 0.0 4.4 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.1 CBZ50914.1 - 0.00016 21.5 0.4 0.0043 16.9 0.1 3.2 2 1 2 4 4 4 3 Tetratricopeptide repeat Apc3 PF12895.2 CBZ50914.1 - 0.0011 19.0 1.5 0.002 18.2 0.5 1.9 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 CBZ50914.1 - 0.021 14.6 0.1 0.17 11.7 0.0 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat Clathrin PF00637.15 CBZ50914.1 - 0.11 12.0 0.3 9.4 5.8 0.1 3.1 2 1 0 3 3 3 0 Region in Clathrin and VPS TPR_8 PF13181.1 CBZ50914.1 - 0.56 10.1 4.2 6.6 6.7 0.1 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat Sua5_yciO_yrdC PF01300.13 CBZ50915.1 - 0.094 11.9 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 Telomere recombination Pkinase PF00069.20 CBZ50919.1 - 8.3e-62 208.6 0.0 9.9e-62 208.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ50919.1 - 9.5e-28 96.9 0.0 1.2e-27 96.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBZ50919.1 - 2.9e-07 29.7 0.0 5.1e-06 25.6 0.0 2.2 1 1 1 2 2 2 1 Kinase-like APH PF01636.18 CBZ50919.1 - 0.00096 18.9 0.2 0.0033 17.1 0.0 1.8 2 1 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 CBZ50919.1 - 0.039 13.5 0.1 0.068 12.7 0.1 1.4 1 1 0 1 1 1 0 Choline/ethanolamine kinase RYDR_ITPR PF01365.16 CBZ50919.1 - 0.042 13.0 0.1 0.083 12.1 0.1 1.5 2 0 0 2 2 2 0 RIH domain Kdo PF06293.9 CBZ50919.1 - 0.052 12.6 0.0 0.089 11.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RRM_5 PF13893.1 CBZ50920.1 - 2.6e-07 30.3 0.0 4.6e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CBZ50920.1 - 0.00064 19.2 0.3 0.0029 17.1 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DnaJ PF00226.26 CBZ50921.1 - 7.4e-26 89.6 6.0 1.1e-25 89.1 4.2 1.2 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 CBZ50921.1 - 1.7e-13 50.2 1.1 4.5e-09 36.0 0.1 2.7 2 1 0 2 2 2 2 DnaJ C terminal domain RRM_6 PF14259.1 CBZ50926.1 - 1.2e-05 25.1 0.0 2.2e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CBZ50926.1 - 2.7e-05 23.7 0.0 5e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ETF_QO PF05187.8 CBZ50928.1 - 2.8e-29 101.3 0.0 4.4e-29 100.6 0.0 1.3 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase NAD_binding_8 PF13450.1 CBZ50928.1 - 4.5e-07 29.8 0.2 1.6e-06 28.0 0.1 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 CBZ50928.1 - 8.2e-06 24.9 1.3 1.1e-05 24.5 0.4 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 CBZ50928.1 - 1.3e-05 24.2 2.4 3.9e-05 22.6 0.6 2.1 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.1 CBZ50928.1 - 7e-05 22.9 0.1 0.00018 21.6 0.1 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 CBZ50928.1 - 7.4e-05 21.3 0.2 0.00011 20.8 0.1 1.2 1 0 0 1 1 1 1 HI0933-like protein NAD_binding_9 PF13454.1 CBZ50928.1 - 0.00025 20.8 0.1 0.00071 19.3 0.1 1.8 1 0 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 CBZ50928.1 - 0.00028 20.8 0.1 0.0006 19.7 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 CBZ50928.1 - 0.0012 17.9 0.1 0.002 17.2 0.1 1.3 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.7 CBZ50928.1 - 0.0017 17.3 0.1 0.0027 16.7 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_3 PF01494.14 CBZ50928.1 - 0.013 14.5 0.2 0.029 13.4 0.0 1.7 2 0 0 2 2 2 0 FAD binding domain FAD_oxidored PF12831.2 CBZ50928.1 - 0.014 14.4 0.2 0.024 13.7 0.1 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase ORC6 PF05460.8 CBZ50928.1 - 0.069 12.2 4.0 0.12 11.4 2.8 1.3 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Trp_halogenase PF04820.9 CBZ50928.1 - 0.11 11.0 0.1 0.17 10.4 0.1 1.2 1 0 0 1 1 1 0 Tryptophan halogenase GIDA PF01134.17 CBZ50928.1 - 0.2 10.5 0.2 0.3 9.9 0.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A GrpE PF01025.14 CBZ50929.1 - 3.7e-44 150.1 11.4 7.2e-44 149.2 7.9 1.5 1 1 0 1 1 1 1 GrpE Herpes_UL6 PF01763.11 CBZ50929.1 - 0.31 9.1 1.8 0.42 8.7 1.3 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like DUF904 PF06005.7 CBZ50929.1 - 5.9 7.2 11.9 0.14 12.4 3.7 1.8 2 1 0 2 2 2 0 Protein of unknown function (DUF904) WD40 PF00400.27 CBZ50930.1 - 1.2e-20 72.5 7.2 5.8e-07 29.1 0.1 7.5 8 0 0 8 8 8 4 WD domain, G-beta repeat Reo_sigmaC PF04582.7 CBZ50930.1 - 0.04 13.0 0.1 0.04 13.0 0.1 2.4 2 1 1 3 3 3 0 Reovirus sigma C capsid protein Peptidase_C48 PF02902.14 CBZ50931.1 - 3.2e-23 82.5 0.0 5.7e-23 81.6 0.0 1.3 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Auxin_BP PF02041.11 CBZ50932.1 - 0.13 11.6 0.0 0.23 10.8 0.0 1.3 1 0 0 1 1 1 0 Auxin binding protein Ank_5 PF13857.1 CBZ50934.1 - 1.7e-11 43.9 0.9 0.00021 21.4 0.0 4.6 5 1 0 5 5 5 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 CBZ50934.1 - 7e-08 32.7 0.1 0.26 11.8 0.0 4.6 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 CBZ50934.1 - 8.6e-08 32.4 0.4 0.053 13.8 0.0 3.7 3 1 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.1 CBZ50934.1 - 0.0016 18.5 2.4 0.21 11.9 0.0 4.1 4 0 0 4 4 4 1 Ankyrin repeat Ank PF00023.25 CBZ50934.1 - 0.0025 17.5 4.9 0.97 9.3 0.0 4.0 4 0 0 4 4 4 2 Ankyrin repeat DUF4475 PF14753.1 CBZ50935.1 - 6.5e-60 202.0 12.0 8.9e-60 201.5 8.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4475) CLAG PF03805.8 CBZ50936.1 - 8.5e-10 36.6 0.2 1.7e-09 35.6 0.0 1.4 2 0 0 2 2 2 1 Cytoadherence-linked asexual protein DUF4040 PF13244.1 CBZ50936.1 - 0.98 9.4 4.7 0.16 11.9 0.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4040) DUF663 PF04950.7 CBZ50937.1 - 2.6e-76 256.4 0.0 1.2e-64 218.0 0.0 2.7 3 0 0 3 3 3 2 Protein of unknown function (DUF663) AARP2CN PF08142.7 CBZ50937.1 - 5e-13 48.3 0.0 1.4e-12 46.9 0.0 1.7 1 0 0 1 1 1 1 AARP2CN (NUC121) domain 2OG-FeII_Oxy_5 PF13759.1 CBZ50937.1 - 0.027 14.7 0.0 16 5.8 0.0 2.8 2 0 0 2 2 2 0 Putative 2OG-Fe(II) oxygenase TTL PF03133.10 CBZ50940.1 - 1.1e-10 40.9 0.0 3.2e-10 39.4 0.0 1.6 2 0 0 2 2 2 1 Tubulin-tyrosine ligase family DUF3661 PF12400.3 CBZ50941.1 - 1.4e-27 96.3 1.5 2.6e-27 95.4 1.1 1.4 1 0 0 1 1 1 1 Vaculolar membrane protein DUF3989 PF13150.1 CBZ50941.1 - 0.12 11.8 0.2 0.29 10.5 0.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3989) EGF_2 PF07974.8 CBZ50944.1 - 0.037 14.2 36.6 0.23 11.6 5.0 4.5 3 0 0 3 3 3 0 EGF-like domain AA_kinase PF00696.23 CBZ50947.1 - 4.6e-33 114.7 0.1 7.3e-33 114.0 0.1 1.3 1 0 0 1 1 1 1 Amino acid kinase family PUA PF01472.15 CBZ50947.1 - 2.1e-13 49.8 0.1 3.5e-09 36.2 0.0 2.7 2 0 0 2 2 2 2 PUA domain Glyco_trans_4_4 PF13579.1 CBZ50947.1 - 0.042 13.9 0.2 0.096 12.8 0.1 1.5 1 0 0 1 1 1 0 Glycosyl transferase 4-like domain Choline_kinase PF01633.15 CBZ50948.1 - 6.4e-41 140.2 0.0 7.4e-23 81.2 0.0 2.2 2 0 0 2 2 2 2 Choline/ethanolamine kinase APH PF01636.18 CBZ50948.1 - 9.3e-14 51.7 0.1 2.3e-08 34.0 0.0 2.7 3 0 0 3 3 3 2 Phosphotransferase enzyme family EcKinase PF02958.15 CBZ50948.1 - 0.0075 15.4 0.0 0.013 14.6 0.0 1.3 1 0 0 1 1 1 1 Ecdysteroid kinase Pkinase PF00069.20 CBZ50948.1 - 0.042 13.0 0.0 0.071 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain DUF1679 PF07914.6 CBZ50948.1 - 0.066 11.8 0.0 0.11 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) DUF1049 PF06305.6 CBZ50951.1 - 0.045 13.2 0.1 0.1 12.1 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) DUF128 PF01995.11 CBZ50951.1 - 0.64 8.8 0.0 0.97 8.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function DUF128 YscO PF07321.7 CBZ50952.1 - 2.1 8.1 9.8 0.064 13.0 1.4 2.0 2 0 0 2 2 2 0 Type III secretion protein YscO Kelch_4 PF13418.1 CBZ50954.1 - 6.5e-19 67.4 15.5 4.2e-08 32.8 0.1 6.7 5 1 1 6 6 6 4 Galactose oxidase, central domain Kelch_3 PF13415.1 CBZ50954.1 - 1.3e-17 63.3 29.7 6.3e-07 29.3 0.1 9.3 10 0 0 10 10 10 4 Galactose oxidase, central domain Kelch_1 PF01344.20 CBZ50954.1 - 3.3e-13 48.9 0.8 0.018 14.5 0.0 5.4 5 0 0 5 5 5 4 Kelch motif Kelch_6 PF13964.1 CBZ50954.1 - 3.8e-12 45.8 11.4 0.00041 20.4 0.1 6.2 6 0 0 6 6 6 3 Kelch motif Kelch_2 PF07646.10 CBZ50954.1 - 6.8e-10 38.3 16.9 0.015 15.0 0.0 8.0 8 0 0 8 8 8 3 Kelch motif Kelch_5 PF13854.1 CBZ50954.1 - 4.7e-09 36.0 13.8 0.0037 17.2 0.0 7.2 7 1 1 8 8 8 3 Kelch motif DUF963 PF06131.6 CBZ50955.1 - 2.2 7.6 20.0 1.2 8.4 11.6 2.2 1 1 0 1 1 1 0 Schizosaccharomyces pombe repeat of unknown function (DUF963) ThiF PF00899.16 CBZ50957.1 - 7.3e-34 116.5 0.0 1.2e-33 115.8 0.0 1.4 1 0 0 1 1 1 1 ThiF family UBACT PF02134.16 CBZ50957.1 - 8.1e-22 76.5 0.1 1.4e-21 75.8 0.0 1.4 1 0 0 1 1 1 1 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 CBZ50957.1 - 5.8e-14 51.1 5.0 8.6e-14 50.6 2.7 1.9 2 0 0 2 2 2 1 Ubiquitin-activating enzyme active site E2_bind PF08825.5 CBZ50957.1 - 3.6e-08 33.0 0.0 8.4e-08 31.8 0.0 1.6 1 0 0 1 1 1 1 E2 binding domain Shikimate_DH PF01488.15 CBZ50957.1 - 8.3e-05 22.7 0.1 0.00025 21.1 0.0 1.9 2 1 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase SNF PF00209.13 CBZ50958.1 - 3.8e-98 329.2 24.1 2.2e-55 188.1 10.0 2.3 2 0 0 2 2 2 2 Sodium:neurotransmitter symporter family zf-rbx1 PF12678.2 CBZ50959.1 - 3.5e-06 27.0 7.2 7.2e-06 26.0 5.0 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 CBZ50959.1 - 3.3e-05 23.6 10.0 7.8e-05 22.4 6.9 1.7 1 0 0 1 1 1 1 Ring finger domain FANCL_C PF11793.3 CBZ50959.1 - 0.00031 20.6 6.0 0.00077 19.3 4.2 1.6 1 0 0 1 1 1 1 FANCL C-terminal domain zf-Apc11 PF12861.2 CBZ50959.1 - 0.0067 16.2 3.6 0.014 15.1 2.5 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING-like PF08746.6 CBZ50959.1 - 0.021 14.8 3.4 0.063 13.2 2.3 1.8 1 0 0 1 1 1 0 RING-like domain zf-C3HC4 PF00097.20 CBZ50959.1 - 0.024 14.2 10.6 0.051 13.2 7.4 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) RINGv PF12906.2 CBZ50959.1 - 0.11 12.5 7.3 0.34 10.9 5.1 1.9 1 0 0 1 1 1 0 RING-variant domain zf-C3HC4_2 PF13923.1 CBZ50959.1 - 0.21 11.6 11.2 0.47 10.5 7.7 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DEAD PF00270.24 CBZ50960.1 - 1.5e-19 70.0 0.0 2.7e-19 69.2 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CBZ50960.1 - 7.9e-16 57.6 0.6 4.5e-15 55.2 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain RQC PF09382.5 CBZ50960.1 - 2.5e-06 27.1 0.0 5.2e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 RQC domain ResIII PF04851.10 CBZ50960.1 - 1.1e-05 25.3 0.0 2.4e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HRDC PF00570.18 CBZ50960.1 - 0.0059 16.2 0.0 0.0059 16.2 0.0 2.5 3 0 0 3 3 3 1 HRDC domain WD40 PF00400.27 CBZ50962.1 - 5.2e-27 92.7 7.2 2.4e-07 30.3 0.0 6.0 6 0 0 6 6 6 5 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 CBZ50962.1 - 1.1e-13 50.8 0.5 2.1e-13 49.9 0.3 1.5 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex AAA_13 PF13166.1 CBZ50963.1 - 0.0034 15.9 9.0 0.0037 15.8 5.8 1.3 1 1 0 1 1 1 1 AAA domain Myosin_tail_1 PF01576.14 CBZ50963.1 - 0.0062 14.3 22.4 0.013 13.2 15.5 1.4 1 1 0 1 1 1 1 Myosin tail Sugarporin_N PF11471.3 CBZ50963.1 - 0.032 13.8 2.8 0.032 13.8 1.9 3.1 3 1 0 3 3 3 0 Maltoporin periplasmic N-terminal extension Laminin_II PF06009.7 CBZ50963.1 - 0.062 13.0 8.5 0.078 12.7 5.0 1.7 1 1 0 1 1 1 0 Laminin Domain II Plasmid_RAQPRD PF09686.5 CBZ50963.1 - 0.11 12.6 0.4 0.11 12.6 0.2 2.3 2 1 0 2 2 2 0 Plasmid protein of unknown function (Plasmid_RAQPRD) APG6 PF04111.7 CBZ50963.1 - 0.14 11.2 14.5 0.17 10.8 10.1 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 zf-C4H2 PF10146.4 CBZ50963.1 - 0.16 11.9 14.8 0.21 11.5 10.2 1.1 1 0 0 1 1 1 0 Zinc finger-containing protein Fib_alpha PF08702.5 CBZ50963.1 - 0.17 12.0 6.8 0.73 9.9 0.9 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family V_ATPase_I PF01496.14 CBZ50963.1 - 0.32 8.7 7.9 0.35 8.6 5.5 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Syntaxin-6_N PF09177.6 CBZ50963.1 - 0.33 11.3 8.3 2.8 8.4 3.0 2.5 1 1 1 2 2 2 0 Syntaxin 6, N-terminal BLOC1_2 PF10046.4 CBZ50963.1 - 0.61 10.2 11.4 0.26 11.4 3.2 2.3 1 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 End3 PF12761.2 CBZ50963.1 - 0.97 9.0 16.0 0.14 11.7 7.5 1.9 1 1 1 2 2 2 0 Actin cytoskeleton-regulatory complex protein END3 Mnd1 PF03962.10 CBZ50963.1 - 1.1 8.8 16.2 1.3 8.6 9.8 1.8 1 1 1 2 2 2 0 Mnd1 family Sec8_exocyst PF04048.9 CBZ50963.1 - 1.3 8.6 8.5 5.5 6.6 0.3 2.7 1 1 1 2 2 2 0 Sec8 exocyst complex component specific domain Med9 PF07544.8 CBZ50963.1 - 1.4 8.7 11.4 0.5 10.1 0.7 2.6 1 1 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 COG2 PF06148.6 CBZ50963.1 - 1.6 8.6 12.9 1.5e+02 2.1 0.0 3.1 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 CENP-Q PF13094.1 CBZ50963.1 - 1.9 8.4 17.5 0.76 9.7 9.8 1.8 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Sec2p PF06428.6 CBZ50963.1 - 2.1 8.2 16.4 1 9.2 6.0 2.4 1 1 1 2 2 2 0 GDP/GTP exchange factor Sec2p Spc7 PF08317.6 CBZ50963.1 - 2.5 6.6 16.3 12 4.4 11.3 1.8 1 1 0 1 1 1 0 Spc7 kinetochore protein KxDL PF10241.4 CBZ50963.1 - 2.9 7.8 8.3 1.5 8.7 2.1 2.6 1 1 2 3 3 3 0 Uncharacterized conserved protein FMN_red PF03358.10 CBZ50963.1 - 3.4 7.1 5.7 1.9 7.9 1.2 2.0 1 1 1 2 2 2 0 NADPH-dependent FMN reductase I_LWEQ PF01608.12 CBZ50963.1 - 3.7 7.4 14.6 0.53 10.2 4.5 2.1 1 1 1 2 2 2 0 I/LWEQ domain Occludin_ELL PF07303.8 CBZ50963.1 - 4.9 7.9 7.9 10 6.8 1.2 2.7 1 1 2 3 3 3 0 Occludin homology domain IncA PF04156.9 CBZ50963.1 - 5 6.6 19.0 11 5.5 12.8 1.8 1 1 0 1 1 1 0 IncA protein TMPIT PF07851.8 CBZ50963.1 - 8 5.4 10.6 3.6 6.5 5.3 1.7 1 1 2 3 3 3 0 TMPIT-like protein SseC PF04888.7 CBZ50963.1 - 9.3 5.4 9.4 1.4 8.2 2.7 2.0 2 0 0 2 2 2 0 Secretion system effector C (SseC) like family FlxA PF14282.1 CBZ50963.1 - 9.8 6.1 9.4 1.4 8.9 1.0 2.4 1 1 0 2 2 2 0 FlxA-like protein DUF3689 PF12463.3 CBZ50964.1 - 9.3e-34 116.5 1.4 1.9e-11 43.3 0.0 5.0 5 0 0 5 5 5 4 Protein of unknown function (DUF3689) DUF1539 PF07560.6 CBZ50964.1 - 1.8 8.4 0.0 3.5 7.4 0.0 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1539) UDPGP PF01704.13 CBZ50965.1 - 9.9e-27 93.4 0.0 1e-20 73.6 0.0 3.0 3 0 0 3 3 3 3 UTP--glucose-1-phosphate uridylyltransferase tRNA_anti-codon PF01336.20 CBZ50966.1 - 0.048 13.5 0.0 5.6 6.9 0.0 2.5 2 0 0 2 2 2 0 OB-fold nucleic acid binding domain Oxysterol_BP PF01237.13 CBZ50967.1 - 2.6e-127 424.1 0.0 4.6e-127 423.3 0.0 1.4 2 0 0 2 2 2 1 Oxysterol-binding protein PH PF00169.24 CBZ50967.1 - 1.9e-07 31.2 0.1 3.2e-07 30.4 0.1 1.4 1 0 0 1 1 1 1 PH domain CENP-Q PF13094.1 CBZ50967.1 - 0.0026 17.7 1.7 0.0071 16.3 1.2 1.6 1 0 0 1 1 1 1 CENP-Q, a CENPA-CAD centromere complex subunit PH_11 PF15413.1 CBZ50967.1 - 0.28 11.4 2.1 9.6 6.4 1.4 2.5 1 1 0 1 1 1 0 Pleckstrin homology domain DUF2428 PF10350.4 CBZ50968.1 - 2.9e-14 52.7 1.0 4e-10 39.1 0.1 3.1 3 0 0 3 3 3 2 Putative death-receptor fusion protein (DUF2428) PAN_3 PF08277.7 CBZ50969.1 - 0.026 14.1 0.0 0.053 13.1 0.0 1.4 1 0 0 1 1 1 0 PAN-like domain PSD5 PF07637.6 CBZ50969.1 - 0.053 13.5 0.0 0.15 12.1 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1595) BCNT PF07572.7 CBZ50972.1 - 3.6e-16 58.8 0.3 3.6e-16 58.8 0.2 2.0 2 0 0 2 2 2 1 Bucentaur or craniofacial development Cyclin_N PF00134.18 CBZ50973.1 - 8.2e-12 44.8 0.1 2.4e-11 43.2 0.0 1.8 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 CBZ50973.1 - 0.0002 21.2 0.0 0.0078 16.1 0.0 2.4 2 0 0 2 2 2 1 Cyclin, C-terminal domain DNA_pol_B PF00136.16 CBZ50974.1 - 2.6e-52 178.1 0.0 2.4e-49 168.3 0.0 2.5 2 1 1 3 3 3 2 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 CBZ50974.1 - 5.7e-08 31.9 0.0 0.0007 18.5 0.0 2.2 2 0 0 2 2 2 2 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.1 CBZ50974.1 - 9.4e-06 25.5 0.7 2.7e-05 24.1 0.5 1.7 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta SAG PF04092.8 CBZ50975.1 - 5.8e-71 236.6 112.5 1.6e-08 35.0 0.0 14.0 12 1 1 13 13 13 11 SRS domain PGM_PMM_I PF02878.11 CBZ50976.1 - 4.9e-17 61.7 0.0 3.2e-07 29.9 0.0 2.6 2 0 0 2 2 2 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_IV PF00408.15 CBZ50976.1 - 4.3e-07 29.8 0.4 2.5e-06 27.3 0.0 2.5 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_II PF02879.11 CBZ50976.1 - 0.00029 21.1 0.1 0.0037 17.5 0.1 2.7 1 1 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II Bromodomain PF00439.20 CBZ50977.1 - 2.2e-15 56.3 0.0 5.2e-15 55.1 0.0 1.6 1 0 0 1 1 1 1 Bromodomain Hid1 PF12722.2 CBZ50977.1 - 1.2 6.6 3.8 1.7 6.1 2.6 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF1754 PF08555.5 CBZ50977.1 - 4.6 7.8 10.8 15 6.2 7.5 1.8 1 0 0 1 1 1 0 Eukaryotic family of unknown function (DUF1754) RRM_1 PF00076.17 CBZ50980.1 - 1e-35 121.1 0.1 1.6e-17 62.9 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBZ50980.1 - 1.9e-25 88.6 0.0 2.1e-11 43.6 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBZ50980.1 - 9.3e-08 31.8 0.0 0.0025 17.6 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 CBZ50980.1 - 0.00099 18.9 0.0 0.35 10.7 0.0 2.3 2 0 0 2 2 2 2 RNA binding motif Nup35_RRM_2 PF14605.1 CBZ50980.1 - 0.012 15.3 0.0 0.088 12.5 0.0 2.1 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif ACDC PF14733.1 CBZ50982.1 - 4.4e-18 65.1 0.2 8.2e-18 64.3 0.1 1.4 1 0 0 1 1 1 1 AP2-coincident C-terminal AP2 PF00847.15 CBZ50982.1 - 3.2e-13 49.6 8.3 1.1e-10 41.4 0.1 3.1 3 0 0 3 3 3 2 AP2 domain Sin_N PF04801.8 CBZ50984.1 - 1.3e-45 156.0 10.0 9.6e-25 87.2 0.0 5.1 4 1 0 4 4 4 3 Sin-like protein conserved region Spore_coat_CotO PF14153.1 CBZ50984.1 - 0.024 14.0 3.5 0.06 12.7 2.4 1.6 1 0 0 1 1 1 0 Spore coat protein CotO DUF1957 PF09210.6 CBZ50984.1 - 0.21 11.6 3.8 3.4 7.7 0.4 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF1957) CDC45 PF02724.9 CBZ50984.1 - 0.37 8.7 8.7 0.61 8.0 6.1 1.3 1 0 0 1 1 1 0 CDC45-like protein Sporozoite_P67 PF05642.6 CBZ50984.1 - 8.6 4.0 11.3 17 3.0 7.9 1.4 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Topoisom_bac PF01131.15 CBZ50985.1 - 1.2e-89 301.0 0.0 1.6e-89 300.5 0.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.17 CBZ50985.1 - 8.4e-16 57.7 0.0 2e-15 56.6 0.0 1.6 1 0 0 1 1 1 1 Toprim domain HypA PF01155.14 CBZ50985.1 - 0.13 11.9 0.1 0.13 11.9 0.1 3.0 2 1 1 3 3 3 0 Hydrogenase expression/synthesis hypA family API5 PF05918.6 CBZ50985.1 - 0.22 9.9 2.0 0.31 9.4 1.4 1.1 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) SRPRB PF09439.5 CBZ50986.1 - 5.3e-23 81.1 0.0 3e-21 75.4 0.0 2.1 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Arf PF00025.16 CBZ50986.1 - 2.8e-14 52.7 0.0 2.3e-12 46.4 0.0 2.1 1 1 0 1 1 1 1 ADP-ribosylation factor family Miro PF08477.8 CBZ50986.1 - 4.1e-06 27.3 0.0 9.9e-06 26.0 0.0 1.7 1 1 0 1 1 1 1 Miro-like protein Ras PF00071.17 CBZ50986.1 - 5.4e-06 25.8 0.0 0.00012 21.5 0.0 2.1 1 1 0 1 1 1 1 Ras family MMR_HSR1 PF01926.18 CBZ50986.1 - 1e-05 25.4 0.0 1.6e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 CBZ50986.1 - 3.3e-05 23.1 0.0 0.00018 20.7 0.0 2.0 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 CBZ50986.1 - 4.9e-05 22.8 0.0 7.8e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain PduV-EutP PF10662.4 CBZ50986.1 - 0.0034 16.8 0.0 0.26 10.7 0.0 2.2 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation ABC_tran PF00005.22 CBZ50986.1 - 0.0036 17.6 0.1 0.01 16.1 0.0 1.8 2 0 0 2 2 2 1 ABC transporter AAA_22 PF13401.1 CBZ50986.1 - 0.0098 16.0 0.0 0.046 13.8 0.0 2.1 1 1 0 1 1 1 1 AAA domain NACHT PF05729.7 CBZ50986.1 - 0.01 15.4 0.4 0.18 11.4 0.3 2.3 1 1 0 1 1 1 0 NACHT domain AAA_16 PF13191.1 CBZ50986.1 - 0.012 15.5 4.8 0.039 13.9 3.3 1.8 1 1 0 1 1 1 0 AAA ATPase domain cobW PF02492.14 CBZ50986.1 - 0.029 13.7 0.3 6.8 6.1 0.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF258 PF03193.11 CBZ50986.1 - 0.076 12.2 0.0 0.13 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_29 PF13555.1 CBZ50986.1 - 0.093 12.2 0.6 0.2 11.2 0.4 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Dynamin_N PF00350.18 CBZ50986.1 - 0.095 12.5 0.0 0.58 9.9 0.0 2.2 2 0 0 2 2 2 0 Dynamin family AAA_28 PF13521.1 CBZ50986.1 - 0.14 12.1 0.0 0.29 11.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain DEAD PF00270.24 CBZ50986.1 - 0.15 11.5 0.0 0.24 10.8 0.0 1.5 1 0 0 1 1 1 0 DEAD/DEAH box helicase AAA_24 PF13479.1 CBZ50986.1 - 0.17 11.4 0.0 0.29 10.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF2529 PF10740.4 CBZ50987.1 - 0.092 12.1 0.1 64 2.9 0.0 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2529) MG1 PF11974.3 CBZ50989.1 - 0.0046 17.4 0.1 1.8 9.1 0.0 2.9 2 0 0 2 2 2 2 Alpha-2-macroglobulin MG1 domain FHA PF00498.21 CBZ50990.1 - 3.3e-11 43.1 0.1 1.4e-10 41.1 0.0 2.1 2 0 0 2 2 2 1 FHA domain RINGv PF12906.2 CBZ50990.1 - 5.1e-07 29.6 4.7 2.8e-06 27.2 3.3 2.1 1 1 0 1 1 1 1 RING-variant domain Cas_CXXC_CXXC PF09706.5 CBZ50991.1 - 0.14 12.3 0.0 0.28 11.3 0.0 1.5 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_CXXC_CXXC) Myb_CC_LHEQLE PF14379.1 CBZ50992.1 - 0.053 13.1 0.5 0.053 13.1 0.4 1.7 2 0 0 2 2 2 0 MYB-CC type transfactor, LHEQLE motif DUF4173 PF13777.1 CBZ50993.1 - 0.084 12.1 4.8 0.12 11.6 3.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4173) Antimicrobial_6 PF08036.6 CBZ50993.1 - 4.7 7.0 5.6 9.3 6.1 0.2 3.3 4 0 0 4 4 4 0 Diapausin family of antimicrobial peptide DUF1035 PF06281.7 CBZ50994.1 - 0.23 11.2 0.1 0.55 10.0 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1035) Clathrin PF00637.15 CBZ50995.1 - 8.6e-14 51.3 0.6 0.28 10.7 0.0 7.9 6 1 2 8 8 8 4 Region in Clathrin and VPS TPR_11 PF13414.1 CBZ50995.1 - 1.9e-06 27.4 20.9 0.16 11.6 0.1 9.0 8 2 1 10 10 10 2 TPR repeat Sec16_C PF12931.2 CBZ50995.1 - 1.5e-05 24.9 0.3 0.042 13.5 0.0 3.4 3 0 0 3 3 3 2 Sec23-binding domain of Sec16 TPR_14 PF13428.1 CBZ50995.1 - 1.5e-05 25.1 49.2 3.6 8.4 0.5 15.0 9 4 7 16 16 16 2 Tetratricopeptide repeat TPR_8 PF13181.1 CBZ50995.1 - 1.6e-05 24.3 6.4 0.59 10.0 0.1 8.2 7 1 0 7 7 7 1 Tetratricopeptide repeat TPR_7 PF13176.1 CBZ50995.1 - 0.00015 21.2 23.5 0.53 10.2 0.0 9.9 7 3 2 9 9 9 1 Tetratricopeptide repeat Nic96 PF04097.9 CBZ50995.1 - 0.0018 16.5 5.4 0.12 10.4 0.1 3.9 3 1 1 5 5 5 2 Nup93/Nic96 DUF742 PF05331.6 CBZ50995.1 - 0.038 13.5 0.2 0.2 11.2 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF742) TPR_12 PF13424.1 CBZ50995.1 - 0.055 13.4 38.3 0.069 13.0 0.2 11.3 7 4 3 11 11 11 0 Tetratricopeptide repeat TPR_16 PF13432.1 CBZ50995.1 - 0.076 13.7 0.1 0.076 13.7 0.1 10.3 7 3 4 11 11 10 0 Tetratricopeptide repeat TPR_1 PF00515.23 CBZ50995.1 - 0.14 11.8 19.1 29 4.4 0.0 9.3 11 0 0 11 11 11 0 Tetratricopeptide repeat TPR_2 PF07719.12 CBZ50995.1 - 2 8.5 42.5 3.9 7.6 0.0 12.9 15 3 2 17 17 17 0 Tetratricopeptide repeat TPR_6 PF13174.1 CBZ50995.1 - 3.1 8.4 20.9 26 5.5 0.2 8.2 9 0 0 9 9 7 0 Tetratricopeptide repeat NHL PF01436.16 CBZ50997.1 - 0.6 10.1 0.0 2.1 8.4 0.0 1.9 2 0 0 2 2 2 0 NHL repeat PUL PF08324.6 CBZ50998.1 - 9.9e-32 109.7 0.0 1.3e-31 109.3 0.0 1.2 1 0 0 1 1 1 1 PUL domain PFU PF09070.6 CBZ50998.1 - 1.6e-27 95.8 0.0 2.8e-27 95.0 0.0 1.4 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) WD40 PF00400.27 CBZ50998.1 - 5.8e-16 57.6 16.3 4.8e-05 23.0 0.0 5.7 5 1 0 5 5 5 4 WD domain, G-beta repeat Chorion_2 PF03964.10 CBZ50998.1 - 0.059 13.9 0.3 0.059 13.9 0.2 2.2 3 0 0 3 3 3 0 Chorion family 2 Trypan_PARP PF05887.6 CBZ50999.1 - 8.4 6.2 11.4 13 5.5 7.9 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) GRIP PF01465.15 CBZ51000.1 - 2.6e-06 26.8 0.0 4.9e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 GRIP domain DUF972 PF06156.8 CBZ51000.1 - 0.32 11.3 13.9 2.3 8.6 0.0 4.4 5 0 0 5 5 5 0 Protein of unknown function (DUF972) Arf PF00025.16 CBZ51002.1 - 5.6e-23 81.0 0.0 2.5e-17 62.6 0.0 2.4 2 1 0 2 2 2 2 ADP-ribosylation factor family SRPRB PF09439.5 CBZ51002.1 - 0.0022 17.2 0.0 0.14 11.3 0.0 2.4 2 1 0 2 2 2 2 Signal recognition particle receptor beta subunit AAA_14 PF13173.1 CBZ51002.1 - 0.14 12.0 0.1 0.32 10.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF4602 PF15375.1 CBZ51003.1 - 6.8e-10 39.1 11.8 6.8e-10 39.1 8.2 2.8 3 0 0 3 3 3 1 Domain of unknown function (DUF4602) EMG1 PF03587.9 CBZ51005.1 - 9.7e-22 77.2 0.0 1.1e-05 24.8 0.0 4.4 4 1 0 4 4 4 4 EMG1/NEP1 methyltransferase GCFC PF07842.7 CBZ51006.1 - 0.048 13.0 0.0 0.065 12.5 0.0 1.1 1 0 0 1 1 1 0 GC-rich sequence DNA-binding factor-like protein DnaB_2 PF07261.6 CBZ51006.1 - 0.053 13.1 0.0 0.1 12.2 0.0 1.5 1 1 0 1 1 1 0 Replication initiation and membrane attachment ADK PF00406.17 CBZ51007.1 - 5.7e-42 143.1 0.0 7.1e-42 142.8 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.1 CBZ51007.1 - 2.7e-09 37.8 0.0 4.4e-09 37.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 CBZ51007.1 - 0.00021 21.1 0.0 0.00037 20.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain ADK_lid PF05191.9 CBZ51007.1 - 0.00062 19.3 0.7 0.0015 18.1 0.5 1.6 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_18 PF13238.1 CBZ51007.1 - 0.019 15.2 0.0 0.12 12.7 0.0 2.4 2 1 0 2 2 2 0 AAA domain AAA_28 PF13521.1 CBZ51007.1 - 0.076 12.9 0.0 0.13 12.1 0.0 1.4 1 1 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 CBZ51007.1 - 0.16 11.1 0.0 0.25 10.4 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI SET PF00856.23 CBZ51008.1 - 2.9e-05 24.4 0.1 0.00022 21.5 0.0 2.6 2 1 0 2 2 2 1 SET domain HypA PF01155.14 CBZ51008.1 - 0.045 13.4 3.0 0.046 13.4 0.2 2.2 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family SAPS PF04499.10 CBZ51009.1 - 5.2 5.5 7.8 8.1 4.9 5.4 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein SynMuv_product PF06047.6 CBZ51010.1 - 2.3e-50 168.6 2.3 2.3e-50 168.6 1.6 3.8 4 0 0 4 4 4 1 Ras-induced vulval development antagonist tRNA-synt_1b PF00579.20 CBZ51011.1 - 5.1e-18 65.2 0.0 3.3e-17 62.5 0.0 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) DUF2874 PF11396.3 CBZ51011.1 - 0.016 15.1 0.1 0.054 13.4 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2874) HSP90 PF00183.13 CBZ51013.1 - 1.5e-260 865.1 37.9 1.7e-260 864.9 26.2 1.0 1 0 0 1 1 1 1 Hsp90 protein HATPase_c_3 PF13589.1 CBZ51013.1 - 1e-12 47.9 0.2 3.4e-12 46.1 0.1 2.0 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 CBZ51013.1 - 1.2e-11 44.3 0.1 2e-11 43.5 0.1 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase LOH1CR12 PF10158.4 CBZ51013.1 - 0.0034 17.1 0.4 0.012 15.4 0.2 1.9 1 0 0 1 1 1 1 Tumour suppressor protein GAGA_bind PF06217.7 CBZ51013.1 - 0.88 9.4 11.5 0.042 13.8 3.4 2.0 2 0 0 2 2 2 0 GAGA binding protein-like family Glycos_transf_2 PF00535.21 CBZ51014.1 - 3.2e-20 72.5 0.1 1.4e-14 54.1 0.0 3.1 2 1 0 2 2 2 2 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 CBZ51014.1 - 1.4e-09 38.1 0.0 1.3e-06 28.3 0.0 2.2 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.4 CBZ51014.1 - 0.0034 16.4 0.0 0.0057 15.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.1 CBZ51014.1 - 0.22 11.8 0.0 0.5 10.7 0.0 1.6 1 0 0 1 1 1 0 Glycosyl transferase family 2 LETM1 PF07766.8 CBZ51015.1 - 1.1e-59 201.6 7.0 1.1e-59 201.6 4.8 1.7 2 0 0 2 2 2 1 LETM1-like protein Pkinase PF00069.20 CBZ51018.1 - 3.5e-43 147.6 0.0 1.1e-42 146.0 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ51018.1 - 1.9e-23 82.8 0.0 3.6e-23 81.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBZ51018.1 - 0.01 14.8 0.0 0.017 14.0 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Aldedh PF00171.17 CBZ51019.1 - 3.9e-35 121.0 0.0 2.7e-18 65.5 0.0 2.1 2 0 0 2 2 2 2 Aldehyde dehydrogenase family Xpo1 PF08389.7 CBZ51020.1 - 0.0033 17.3 0.2 0.03 14.2 0.0 2.7 2 0 0 2 2 2 1 Exportin 1-like protein DDT PF02791.12 CBZ51020.1 - 0.0064 16.2 0.0 0.032 13.9 0.0 2.2 1 0 0 1 1 1 1 DDT domain Cas_Csd1 PF09709.5 CBZ51021.1 - 0.28 9.4 0.0 0.43 8.8 0.0 1.1 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csd1) DAO PF01266.19 CBZ51022.1 - 1.6e-21 76.6 0.0 2.2e-21 76.1 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Mqo PF06039.10 CBZ51022.1 - 3e-19 68.5 0.0 1e-18 66.8 0.0 1.6 1 1 0 1 1 1 1 Malate:quinone oxidoreductase (Mqo) NAD_binding_8 PF13450.1 CBZ51022.1 - 0.022 14.7 0.0 0.05 13.6 0.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 CBZ51022.1 - 0.027 14.2 0.1 1.9 8.2 0.0 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 CBZ51022.1 - 0.037 14.0 0.0 11 6.0 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase UCH PF00443.24 CBZ51023.1 - 0.00028 20.0 0.0 0.00032 19.8 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase AAA PF00004.24 CBZ51024.1 - 2.1e-32 112.0 0.0 4.2e-32 111.1 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 CBZ51024.1 - 1.8e-07 31.3 0.0 5e-07 29.9 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 CBZ51024.1 - 5.3e-06 27.2 0.0 9.5e-06 26.4 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 CBZ51024.1 - 1.4e-05 25.2 0.6 9.7e-05 22.4 0.4 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.1 CBZ51024.1 - 7.3e-05 23.0 0.0 0.00015 22.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 CBZ51024.1 - 0.00014 21.7 0.0 0.00032 20.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 CBZ51024.1 - 0.00027 20.8 0.0 0.00054 19.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 CBZ51024.1 - 0.00038 20.1 0.0 0.00094 18.8 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_5 PF07728.9 CBZ51024.1 - 0.00063 19.4 0.1 0.002 17.8 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Arch_ATPase PF01637.13 CBZ51024.1 - 0.00084 19.1 0.1 0.85 9.2 0.0 2.2 1 1 1 2 2 2 2 Archaeal ATPase UPF0079 PF02367.12 CBZ51024.1 - 0.0031 17.1 0.0 0.0057 16.2 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised P-loop hydrolase UPF0079 RNA_helicase PF00910.17 CBZ51024.1 - 0.0047 17.0 0.2 0.011 15.8 0.0 1.8 2 0 0 2 2 1 1 RNA helicase NACHT PF05729.7 CBZ51024.1 - 0.0055 16.3 0.2 0.026 14.1 0.1 2.1 1 1 0 1 1 1 1 NACHT domain IstB_IS21 PF01695.12 CBZ51024.1 - 0.0066 15.8 0.0 0.012 15.0 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein KAP_NTPase PF07693.9 CBZ51024.1 - 0.0074 15.3 0.1 0.51 9.2 0.0 2.3 2 1 1 3 3 3 1 KAP family P-loop domain AAA_28 PF13521.1 CBZ51024.1 - 0.0089 15.9 0.0 0.018 14.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 CBZ51024.1 - 0.009 15.0 0.0 0.016 14.2 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_24 PF13479.1 CBZ51024.1 - 0.011 15.3 0.0 0.021 14.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.13 CBZ51024.1 - 0.012 15.1 0.0 0.024 14.1 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_11 PF13086.1 CBZ51024.1 - 0.016 14.8 0.0 0.023 14.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 CBZ51024.1 - 0.018 14.4 0.0 0.041 13.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.10 CBZ51024.1 - 0.031 12.9 0.0 0.05 12.2 0.0 1.4 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein TIP49 PF06068.8 CBZ51024.1 - 0.034 12.8 0.0 0.051 12.2 0.0 1.2 1 0 0 1 1 1 0 TIP49 C-terminus Mg_chelatase PF01078.16 CBZ51024.1 - 0.043 12.9 0.0 0.13 11.4 0.0 1.7 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.7 CBZ51024.1 - 0.045 12.8 0.0 0.073 12.1 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_3 PF07726.6 CBZ51024.1 - 0.048 13.2 0.0 0.13 11.8 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.1 CBZ51024.1 - 0.061 12.8 0.0 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_2 PF07724.9 CBZ51024.1 - 0.08 12.8 0.0 0.2 11.5 0.0 1.7 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) DUF815 PF05673.8 CBZ51024.1 - 0.081 11.8 0.0 0.28 10.0 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF815) DUF2075 PF09848.4 CBZ51024.1 - 0.11 11.4 0.0 0.16 10.8 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) SKI PF01202.17 CBZ51024.1 - 0.12 12.2 0.0 0.25 11.2 0.0 1.6 1 0 0 1 1 1 0 Shikimate kinase KTI12 PF08433.5 CBZ51024.1 - 0.12 11.5 0.0 0.2 10.8 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_35 PF14516.1 CBZ51024.1 - 0.13 10.9 0.0 0.19 10.3 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain ABC_tran PF00005.22 CBZ51024.1 - 0.15 12.3 0.0 0.3 11.3 0.0 1.4 1 0 0 1 1 1 0 ABC transporter PhoH PF02562.11 CBZ51024.1 - 0.21 10.7 0.0 0.47 9.6 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein Nol1_Nop2_Fmu PF01189.12 CBZ51025.1 - 1.7e-85 286.8 0.0 2.4e-85 286.3 0.0 1.2 1 0 0 1 1 1 1 NOL1/NOP2/sun family PCMT PF01135.14 CBZ51025.1 - 0.004 16.7 0.1 0.025 14.1 0.0 2.0 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) FtsJ PF01728.14 CBZ51025.1 - 0.028 14.3 0.0 0.054 13.4 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase Nucleoside_tran PF01733.13 CBZ51026.1 - 3.5e-20 72.4 9.1 2.5e-15 56.4 3.7 2.3 2 0 0 2 2 2 2 Nucleoside transporter DUF106 PF01956.11 CBZ51026.1 - 9.5 5.7 7.5 3.5 7.1 0.2 2.9 1 1 1 2 2 2 0 Integral membrane protein DUF106 Ank_2 PF12796.2 CBZ51027.1 - 0.0094 16.2 0.0 0.02 15.1 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 CBZ51027.1 - 0.089 13.0 0.0 1.9 8.8 0.0 2.6 1 1 1 2 2 2 0 Ankyrin repeats (many copies) IncA PF04156.9 CBZ51029.1 - 0.97 8.9 7.9 1.8 8.1 5.4 1.4 1 0 0 1 1 1 0 IncA protein Methyltransf_18 PF12847.2 CBZ51030.1 - 2.9e-11 43.9 0.0 4.5e-11 43.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 CBZ51030.1 - 3.3e-09 36.7 0.1 5.3e-09 36.1 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CBZ51030.1 - 9.6e-09 34.9 0.0 1.3e-08 34.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CBZ51030.1 - 9.8e-07 29.1 0.0 1.6e-06 28.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 CBZ51030.1 - 1.6e-06 27.6 0.0 2.4e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.15 CBZ51030.1 - 1.6e-05 24.1 0.0 2.2e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.7 CBZ51030.1 - 5.1e-05 23.6 0.0 8.4e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CBZ51030.1 - 0.00011 21.9 0.2 0.00051 19.8 0.0 1.8 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 CBZ51030.1 - 0.00012 22.3 0.0 0.00023 21.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.13 CBZ51030.1 - 0.00016 21.2 0.0 0.00024 20.7 0.0 1.2 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 DOT1 PF08123.8 CBZ51030.1 - 0.00019 20.7 0.0 0.00037 19.8 0.0 1.4 1 1 0 1 1 1 1 Histone methylation protein DOT1 RrnaAD PF00398.15 CBZ51030.1 - 0.0002 20.5 0.0 0.0003 19.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_4 PF02390.12 CBZ51030.1 - 0.00029 19.9 0.1 0.0011 18.0 0.0 1.9 1 1 0 1 1 1 1 Putative methyltransferase PrmA PF06325.8 CBZ51030.1 - 0.0013 17.9 0.1 0.002 17.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MetW PF07021.7 CBZ51030.1 - 0.0049 16.2 0.1 0.0081 15.5 0.1 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_32 PF13679.1 CBZ51030.1 - 0.0053 16.4 0.1 0.008 15.8 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.10 CBZ51030.1 - 0.026 14.1 0.0 0.039 13.5 0.0 1.2 1 0 0 1 1 1 0 Hypothetical methyltransferase PCMT PF01135.14 CBZ51030.1 - 0.028 13.9 0.0 0.045 13.2 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_9 PF08003.6 CBZ51030.1 - 0.028 13.1 0.1 0.057 12.1 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1698) AdoMet_MTase PF07757.8 CBZ51030.1 - 0.048 13.7 0.0 1.8 8.6 0.0 2.2 2 0 0 2 2 2 0 Predicted AdoMet-dependent methyltransferase Ribosomal_L21p PF00829.16 CBZ51033.1 - 1.1e-16 60.7 0.0 1.4e-16 60.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal prokaryotic L21 protein Evr1_Alr PF04777.8 CBZ51034.1 - 8.6e-19 67.2 0.9 1.3e-18 66.6 0.6 1.2 1 0 0 1 1 1 1 Erv1 / Alr family NAP PF00956.13 CBZ51035.1 - 3.4e-37 127.8 0.2 3.4e-37 127.8 0.1 1.5 2 0 0 2 2 2 1 Nucleosome assembly protein (NAP) Lge1 PF11488.3 CBZ51035.1 - 0.069 13.3 0.6 0.15 12.2 0.4 1.6 1 0 0 1 1 1 0 Transcriptional regulatory protein LGE1 Radical_SAM PF04055.16 CBZ51036.1 - 1.6e-14 54.4 0.0 4.7e-14 52.8 0.0 1.7 1 1 0 1 1 1 1 Radical SAM superfamily AP_endonuc_2 PF01261.19 CBZ51039.1 - 7.8e-20 71.0 0.0 1.7e-19 69.9 0.0 1.7 1 1 0 1 1 1 1 Xylose isomerase-like TIM barrel HSCB_C PF07743.8 CBZ51040.1 - 5e-08 33.2 3.6 8.4e-08 32.5 2.5 1.4 1 0 0 1 1 1 1 HSCB C-terminal oligomerisation domain DnaJ PF00226.26 CBZ51040.1 - 0.0016 18.1 0.1 0.003 17.2 0.1 1.5 1 1 0 1 1 1 1 DnaJ domain CK_II_beta PF01214.13 CBZ51040.1 - 0.011 15.2 1.4 0.098 12.1 0.2 2.1 2 0 0 2 2 2 0 Casein kinase II regulatory subunit DZR PF12773.2 CBZ51040.1 - 0.039 13.7 0.9 0.066 13.0 0.7 1.3 1 0 0 1 1 1 0 Double zinc ribbon RNA_POL_M_15KD PF02150.11 CBZ51040.1 - 0.058 13.0 0.0 0.16 11.7 0.0 1.7 1 0 0 1 1 1 0 RNA polymerases M/15 Kd subunit zf-B_box PF00643.19 CBZ51040.1 - 0.063 13.1 0.8 0.099 12.5 0.6 1.3 1 0 0 1 1 1 0 B-box zinc finger zf-ribbon_3 PF13248.1 CBZ51040.1 - 0.071 12.3 1.6 0.13 11.5 1.1 1.3 1 0 0 1 1 1 0 zinc-ribbon domain Spectrin PF00435.16 CBZ51040.1 - 0.19 12.0 1.7 1.6 9.0 0.1 2.2 1 1 1 2 2 2 0 Spectrin repeat SMC_N PF02463.14 CBZ51041.1 - 4.7e-43 146.9 0.0 2.1e-41 141.5 0.0 3.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 CBZ51041.1 - 1.5e-28 99.1 0.0 6.2e-26 90.7 0.0 3.5 3 0 0 3 3 3 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.1 CBZ51041.1 - 1.7e-13 51.3 0.5 1.7e-13 51.3 0.4 6.9 3 2 0 4 4 4 1 AAA domain AAA_21 PF13304.1 CBZ51041.1 - 7.2e-12 45.8 0.0 0.00012 22.1 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 CBZ51041.1 - 0.0002 20.8 0.9 0.00028 20.3 0.0 1.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA PF00004.24 CBZ51041.1 - 0.0036 17.5 3.0 0.064 13.4 0.0 4.2 4 0 0 4 4 4 1 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.22 CBZ51041.1 - 0.12 12.6 0.0 0.12 12.6 0.0 5.6 6 1 0 6 6 6 0 ABC transporter PDGLE PF13190.1 CBZ51041.1 - 0.19 11.4 0.2 1.3 8.7 0.1 2.7 2 0 0 2 2 2 0 PDGLE domain AAA_17 PF13207.1 CBZ51041.1 - 0.22 12.3 0.0 0.22 12.3 0.0 4.2 4 1 0 4 4 4 0 AAA domain PgaD PF13994.1 CBZ51042.1 - 0.094 12.1 0.3 0.17 11.3 0.2 1.4 1 0 0 1 1 1 0 PgaD-like protein Ribosomal_L16 PF00252.13 CBZ51043.1 - 2.1e-31 108.3 0.0 2.8e-31 108.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e DNA_pol_B_thumb PF14791.1 CBZ51044.1 - 2.9e-15 55.6 0.0 6e-08 32.2 0.0 2.8 2 0 0 2 2 2 2 DNA polymerase beta thumb DNA_pol_B_palm PF14792.1 CBZ51044.1 - 2.7e-14 53.1 0.5 2.6e-11 43.5 0.0 3.6 3 1 0 3 3 3 1 DNA polymerase beta palm DNA_pol_lambd_f PF10391.4 CBZ51044.1 - 2e-06 27.2 0.1 0.00047 19.6 0.0 2.5 2 0 0 2 2 2 2 Fingers domain of DNA polymerase lambda HHH_5 PF14520.1 CBZ51044.1 - 6.4e-05 23.0 0.0 0.00026 21.0 0.0 2.0 2 0 0 2 2 2 1 Helix-hairpin-helix domain Cdd1 PF11731.3 CBZ51044.1 - 0.051 13.5 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 Pathogenicity locus Asparaginase PF00710.15 CBZ51045.1 - 3.3e-85 285.7 0.0 4.3e-85 285.3 0.0 1.1 1 0 0 1 1 1 1 Asparaginase UCR_14kD PF02271.11 CBZ51046.1 - 1e-12 47.7 0.1 1.6e-12 47.1 0.0 1.3 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit Exo_endo_phos PF03372.18 CBZ51047.1 - 8.9e-08 32.3 0.2 2.6e-07 30.8 0.1 1.9 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Mg_trans_NIPA PF05653.9 CBZ51048.1 - 3.2e-26 92.0 11.9 9.8e-26 90.4 8.3 1.6 1 1 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.15 CBZ51048.1 - 1.1e-07 31.8 24.0 0.00022 21.2 3.6 2.8 2 1 1 3 3 3 2 EamA-like transporter family EmrE PF13536.1 CBZ51048.1 - 1.8e-06 28.1 18.8 9.8e-06 25.7 3.8 2.7 2 0 0 2 2 2 2 Multidrug resistance efflux transporter UPF0546 PF10639.4 CBZ51048.1 - 0.0068 16.2 4.3 0.018 14.8 0.3 2.3 2 0 0 2 2 2 1 Uncharacterised protein family UPF0546 Pyr_redox_2 PF07992.9 CBZ51049.1 - 8.8e-23 81.2 0.0 1.3e-22 80.6 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 CBZ51049.1 - 4.3e-10 39.8 0.0 8e-09 35.7 0.0 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 CBZ51049.1 - 0.036 14.1 0.0 1.1 9.3 0.0 2.5 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase COPI_assoc PF08507.5 CBZ51051.1 - 5.2e-07 29.4 7.4 6.3e-07 29.1 5.2 1.1 1 0 0 1 1 1 1 COPI associated protein DUF1206 PF06724.6 CBZ51051.1 - 5.7 6.7 9.0 4.7 7.0 0.4 2.8 2 1 0 2 2 2 0 Domain of Unknown Function (DUF1206) TIP49 PF06068.8 CBZ51052.1 - 5.7e-176 585.0 0.7 6.8e-176 584.8 0.5 1.0 1 0 0 1 1 1 1 TIP49 C-terminus AAA PF00004.24 CBZ51052.1 - 1.4e-12 47.9 0.8 4.9e-08 33.2 0.1 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 CBZ51052.1 - 1.3e-08 34.1 1.5 1.1e-05 24.5 0.0 2.8 2 1 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 CBZ51052.1 - 1.5e-08 34.8 0.2 3.7e-07 30.3 0.1 2.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 CBZ51052.1 - 1.7e-07 31.4 0.1 0.014 15.5 0.1 2.7 2 1 0 2 2 2 2 AAA domain Zeta_toxin PF06414.7 CBZ51052.1 - 2.5e-06 26.7 0.1 7.2e-06 25.2 0.0 1.8 2 0 0 2 2 1 1 Zeta toxin DnaB_C PF03796.10 CBZ51052.1 - 7.3e-06 25.0 0.1 1.5e-05 24.0 0.1 1.5 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_5 PF07728.9 CBZ51052.1 - 1.1e-05 25.2 0.1 0.016 14.8 0.0 2.9 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 CBZ51052.1 - 5.6e-05 22.3 0.5 0.0036 16.4 0.1 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_17 PF13207.1 CBZ51052.1 - 7.6e-05 23.5 0.0 0.00018 22.2 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.1 CBZ51052.1 - 0.00043 19.7 0.0 0.0024 17.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 CBZ51052.1 - 0.00056 20.2 0.0 0.0024 18.1 0.0 2.2 2 0 0 2 2 1 1 AAA domain NACHT PF05729.7 CBZ51052.1 - 0.00069 19.3 0.0 0.0014 18.3 0.0 1.5 1 0 0 1 1 1 1 NACHT domain Sigma54_activat PF00158.21 CBZ51052.1 - 0.0012 18.3 0.2 0.71 9.3 0.0 2.6 2 1 0 2 2 2 1 Sigma-54 interaction domain AAA_19 PF13245.1 CBZ51052.1 - 0.0022 17.6 0.1 0.0074 16.0 0.0 2.0 2 0 0 2 2 1 1 Part of AAA domain AAA_14 PF13173.1 CBZ51052.1 - 0.0026 17.6 0.0 2.5 7.9 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.1 CBZ51052.1 - 0.0029 17.4 0.1 0.012 15.5 0.0 2.1 2 0 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.13 CBZ51052.1 - 0.0042 16.5 0.1 0.16 11.4 0.0 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family DUF2075 PF09848.4 CBZ51052.1 - 0.013 14.5 0.1 0.025 13.5 0.0 1.5 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) KTI12 PF08433.5 CBZ51052.1 - 0.013 14.7 0.0 0.023 13.9 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Zot PF05707.7 CBZ51052.1 - 0.023 14.1 0.1 1.6 8.1 0.0 2.3 2 0 0 2 2 2 0 Zonular occludens toxin (Zot) APS_kinase PF01583.15 CBZ51052.1 - 0.026 14.2 0.0 0.054 13.1 0.0 1.6 1 0 0 1 1 1 0 Adenylylsulphate kinase KaiC PF06745.8 CBZ51052.1 - 0.038 13.1 2.5 0.047 12.8 0.0 2.3 3 0 0 3 3 3 0 KaiC UPF0079 PF02367.12 CBZ51052.1 - 0.043 13.4 0.1 0.1 12.2 0.1 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 CPT PF07931.7 CBZ51052.1 - 0.058 13.0 0.0 0.2 11.2 0.0 1.9 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein Sigma54_activ_2 PF14532.1 CBZ51052.1 - 0.087 12.8 0.0 0.67 9.9 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_29 PF13555.1 CBZ51052.1 - 0.095 12.2 0.1 0.35 10.4 0.0 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain DEAD PF00270.24 CBZ51052.1 - 0.12 11.9 0.4 0.35 10.3 0.1 1.9 2 0 0 2 2 2 0 DEAD/DEAH box helicase RNA_helicase PF00910.17 CBZ51052.1 - 0.15 12.2 0.0 0.87 9.7 0.0 2.3 3 0 0 3 3 2 0 RNA helicase ChaB PF06150.7 CBZ51053.1 - 3.9 7.3 5.2 0.48 10.2 0.2 2.1 2 0 0 2 2 2 0 ChaB Spc97_Spc98 PF04130.8 CBZ51054.1 - 0.0039 15.5 0.0 0.024 12.9 0.0 2.3 2 0 0 2 2 2 1 Spc97 / Spc98 family DUF866 PF05907.8 CBZ51055.1 - 6e-24 84.3 0.0 1.1e-23 83.5 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) ABC_tran PF00005.22 CBZ51056.1 - 4.8e-21 75.4 0.0 9.9e-21 74.4 0.0 1.6 1 0 0 1 1 1 1 ABC transporter ABC2_membrane PF01061.19 CBZ51056.1 - 6.7e-19 67.8 17.6 1.1e-18 67.1 12.2 1.3 1 0 0 1 1 1 1 ABC-2 type transporter AAA_25 PF13481.1 CBZ51056.1 - 1.1e-07 31.5 0.1 4.9e-05 22.8 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 CBZ51056.1 - 4.8e-06 26.6 0.0 1.3e-05 25.2 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 CBZ51056.1 - 4e-05 23.7 0.0 9.4e-05 22.5 0.0 1.6 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 CBZ51056.1 - 0.0005 19.3 0.0 0.00092 18.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_17 PF13207.1 CBZ51056.1 - 0.00077 20.2 0.0 0.0019 18.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain ABC2_membrane_3 PF12698.2 CBZ51056.1 - 0.0067 15.5 13.4 0.0094 15.0 9.3 1.2 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_28 PF13521.1 CBZ51056.1 - 0.012 15.5 0.0 0.03 14.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 CBZ51056.1 - 0.014 15.0 0.0 0.023 14.4 0.0 1.2 1 0 0 1 1 1 0 Archaeal ATPase AAA_18 PF13238.1 CBZ51056.1 - 0.022 15.0 0.0 0.041 14.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_21 PF13304.1 CBZ51056.1 - 0.024 14.5 0.0 0.39 10.6 0.0 2.1 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.1 CBZ51056.1 - 0.027 14.0 0.0 0.084 12.4 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_19 PF13245.1 CBZ51056.1 - 0.032 13.9 0.0 0.15 11.8 0.0 2.1 1 0 0 1 1 1 0 Part of AAA domain AAA PF00004.24 CBZ51056.1 - 0.046 13.9 0.0 0.082 13.1 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 CBZ51056.1 - 0.063 12.9 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_10 PF12846.2 CBZ51056.1 - 0.074 12.4 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain MobB PF03205.9 CBZ51056.1 - 0.16 11.6 0.0 0.29 10.8 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B RNA_helicase PF00910.17 CBZ51056.1 - 0.17 12.0 0.0 0.32 11.1 0.0 1.4 1 0 0 1 1 1 0 RNA helicase AAA_14 PF13173.1 CBZ51056.1 - 0.19 11.6 0.0 0.32 10.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain cobW PF02492.14 CBZ51056.1 - 0.2 11.0 0.0 0.35 10.2 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Rad17 PF03215.10 CBZ51056.1 - 0.52 8.9 0.0 0.78 8.3 0.0 1.1 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein Cnd2 PF05786.9 CBZ51057.1 - 1.7e-28 99.6 1.3 1.1e-20 73.8 0.2 3.4 3 0 0 3 3 3 3 Condensin complex subunit 2 XK-related PF09815.4 CBZ51058.1 - 1.7 7.5 0.2 2.6 6.9 0.1 1.2 1 0 0 1 1 1 0 XK-related protein DUF2500 PF10694.4 CBZ51058.1 - 8.9 6.3 1.3 24 4.9 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2500) HHH_5 PF14520.1 CBZ51062.1 - 8.9e-06 25.7 0.1 1.8e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Helix-hairpin-helix domain IGR PF09597.5 CBZ51062.1 - 0.00018 21.3 0.2 0.0011 18.8 0.0 2.3 2 0 0 2 2 2 1 IGR protein motif HHH_2 PF12826.2 CBZ51062.1 - 0.00061 19.6 0.1 0.0014 18.5 0.1 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix motif SAM_1 PF00536.25 CBZ51062.1 - 0.0024 18.0 0.2 0.0065 16.6 0.0 1.7 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) Myb_DNA-bind_6 PF13921.1 CBZ51062.1 - 0.0073 16.3 0.1 0.017 15.2 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain DUF305 PF03713.8 CBZ51063.1 - 0.15 11.9 0.1 0.15 11.9 0.0 2.1 3 0 0 3 3 3 0 Domain of unknown function (DUF305) CwfJ_C_1 PF04677.10 CBZ51064.1 - 1.2e-26 92.7 0.1 2.3e-26 91.8 0.1 1.4 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 RRM_1 PF00076.17 CBZ51064.1 - 2.2e-10 40.0 0.0 3.8e-10 39.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBZ51064.1 - 4.3e-06 26.6 0.0 9e-06 25.5 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBZ51064.1 - 0.22 11.3 0.0 0.43 10.4 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3584 PF12128.3 CBZ51065.1 - 0.077 10.3 44.8 0.1 9.8 31.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Spc7 PF08317.6 CBZ51065.1 - 7.3 5.1 43.9 0.021 13.4 10.8 2.5 1 1 1 2 2 2 0 Spc7 kinetochore protein Arm PF00514.18 CBZ51066.1 - 2.8e-08 33.2 10.3 0.34 10.8 0.0 10.6 11 0 0 11 11 11 1 Armadillo/beta-catenin-like repeat V-ATPase_H_N PF03224.9 CBZ51066.1 - 0.00036 19.7 3.4 0.057 12.5 0.1 4.7 3 2 0 4 4 4 1 V-ATPase subunit H KAP PF05804.7 CBZ51066.1 - 0.0056 14.6 0.2 0.22 9.3 0.0 2.4 2 0 0 2 2 2 2 Kinesin-associated protein (KAP) Arm_2 PF04826.8 CBZ51066.1 - 0.025 13.7 0.0 1.2 8.1 0.0 2.9 2 0 0 2 2 2 0 Armadillo-like HEAT PF02985.17 CBZ51066.1 - 0.031 14.3 10.9 21 5.5 0.3 7.3 7 0 0 7 7 7 0 HEAT repeat HEAT_EZ PF13513.1 CBZ51066.1 - 0.12 12.9 6.8 13 6.4 0.2 6.4 5 0 0 5 5 5 0 HEAT-like repeat Pkinase PF00069.20 CBZ51067.1 - 3.6e-13 49.2 0.0 1.5e-05 24.2 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ51067.1 - 9.2e-05 21.6 0.0 0.061 12.3 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.9 CBZ51067.1 - 0.034 13.2 0.0 0.059 12.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 CBZ51067.1 - 0.37 9.6 0.2 1.7 7.5 0.1 1.9 2 0 0 2 2 2 0 Kinase-like E1-E2_ATPase PF00122.15 CBZ51070.1 - 2.2e-19 69.4 0.2 5.2e-18 64.9 0.0 2.4 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 CBZ51070.1 - 2e-16 61.0 0.0 6.6e-06 26.6 0.0 3.3 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase HAD PF12710.2 CBZ51070.1 - 3e-12 47.1 0.0 7.8e-06 26.1 0.0 3.0 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 CBZ51070.1 - 0.034 13.6 0.0 0.14 11.6 0.0 2.0 1 0 0 1 1 1 0 Cation transporter/ATPase, N-terminus Adaptin_N PF01602.15 CBZ51071.1 - 8.9e-75 251.9 0.0 1e-42 146.1 2.9 2.7 3 0 0 3 3 3 2 Adaptin N terminal region HEAT_2 PF13646.1 CBZ51071.1 - 7e-05 23.0 17.2 0.00027 21.1 1.1 5.2 4 2 1 5 5 5 1 HEAT repeats Cnd1 PF12717.2 CBZ51071.1 - 0.00011 22.0 3.5 0.0054 16.5 1.2 2.9 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.17 CBZ51071.1 - 0.0024 17.8 20.5 1.3 9.2 0.0 7.6 8 0 0 8 8 8 2 HEAT repeat Arm PF00514.18 CBZ51071.1 - 0.076 12.8 10.8 17 5.3 0.1 5.3 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat HOOK PF05622.7 CBZ51072.1 - 2.9e-13 48.5 81.0 1.4e-12 46.3 56.2 2.6 1 1 0 1 1 1 1 HOOK protein Reo_sigmaC PF04582.7 CBZ51072.1 - 8.9 5.3 24.2 0.3 10.2 0.6 4.3 1 1 2 4 4 4 0 Reovirus sigma C capsid protein DUF641 PF04859.7 CBZ51074.1 - 0.0071 16.1 11.2 0.0099 15.6 2.5 2.7 1 1 1 2 2 2 2 Plant protein of unknown function (DUF641) V_ATPase_I PF01496.14 CBZ51074.1 - 2.2 6.0 1.3 3.7 5.3 0.9 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family End3 PF12761.2 CBZ51074.1 - 9.5 5.8 12.0 2.6 7.6 5.9 1.8 2 0 0 2 2 2 0 Actin cytoskeleton-regulatory complex protein END3 PRP21_like_P PF12230.3 CBZ51075.1 - 0.48 9.8 9.0 1 8.8 6.2 1.4 1 0 0 1 1 1 0 Pre-mRNA splicing factor PRP21 like protein DUF4139 PF13598.1 CBZ51075.1 - 3.7 6.7 18.9 0.11 11.7 1.8 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4139) RR_TM4-6 PF06459.7 CBZ51075.1 - 4 7.2 10.7 8.1 6.2 7.4 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 L51_S25_CI-B8 PF05047.11 CBZ51076.1 - 0.0049 16.5 0.3 0.0091 15.7 0.2 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain Guanylate_cyc PF00211.15 CBZ51078.1 - 3e-19 69.1 0.1 4.9e-19 68.3 0.0 1.2 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Ion_trans PF00520.26 CBZ51078.1 - 3.9e-05 23.0 0.2 3.9e-05 23.0 0.2 1.9 2 0 0 2 2 2 1 Ion transport protein Toxin_1 PF00087.16 CBZ51078.1 - 0.33 11.3 1.9 0.65 10.4 1.3 1.4 1 0 0 1 1 1 0 Snake toxin Thioredoxin_8 PF13905.1 CBZ51079.1 - 1e-20 73.6 0.0 1.7e-20 72.9 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.1 CBZ51079.1 - 2.6e-08 34.0 0.0 3.9e-08 33.4 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like domain AhpC-TSA PF00578.16 CBZ51079.1 - 9.2e-06 25.3 0.0 1.3e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin PF00085.15 CBZ51079.1 - 0.012 15.2 0.1 0.47 10.1 0.1 2.1 1 1 1 2 2 2 0 Thioredoxin Thioredoxin_7 PF13899.1 CBZ51079.1 - 0.037 14.0 0.0 0.06 13.3 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin-like Redoxin PF08534.5 CBZ51079.1 - 0.038 13.5 0.0 0.091 12.3 0.0 1.7 2 0 0 2 2 2 0 Redoxin TPR_11 PF13414.1 CBZ51080.1 - 2.9e-17 62.0 11.2 7.4e-10 38.3 0.3 4.2 2 1 2 4 4 4 3 TPR repeat TPR_1 PF00515.23 CBZ51080.1 - 4.7e-14 51.2 0.3 3.6e-05 23.1 0.6 4.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 CBZ51080.1 - 1.1e-11 43.7 16.2 5.7e-05 22.7 1.1 6.6 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_8 PF13181.1 CBZ51080.1 - 8.5e-10 37.7 0.0 0.0095 15.6 0.2 4.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 CBZ51080.1 - 3.5e-08 32.6 8.4 0.0031 17.1 0.2 5.5 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_16 PF13432.1 CBZ51080.1 - 4.1e-08 33.6 3.2 4.1e-08 33.6 2.2 6.7 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_9 PF13371.1 CBZ51080.1 - 3.5e-07 29.9 3.0 3.5e-07 29.9 2.0 3.6 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.1 CBZ51080.1 - 2.3e-06 27.4 12.7 0.0011 18.8 1.3 4.9 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.1 CBZ51080.1 - 0.00023 21.4 0.5 0.00023 21.4 0.3 4.8 5 0 0 5 5 5 1 Tetratricopeptide repeat Apc3 PF12895.2 CBZ51080.1 - 0.00039 20.5 3.4 0.0014 18.7 0.3 3.0 3 0 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.1 CBZ51080.1 - 0.00093 19.6 8.4 0.0071 16.8 0.8 7.9 7 1 0 7 7 6 2 Tetratricopeptide repeat TPR_17 PF13431.1 CBZ51080.1 - 0.0051 16.9 5.2 5.5 7.4 0.0 4.9 5 1 1 6 6 5 2 Tetratricopeptide repeat Borrelia_P83 PF05262.6 CBZ51080.1 - 0.27 9.4 5.2 0.55 8.4 3.6 1.4 1 0 0 1 1 1 0 Borrelia P83/100 protein TPR_6 PF13174.1 CBZ51080.1 - 2.3 8.8 6.4 56 4.5 0.0 5.2 5 1 0 5 5 4 0 Tetratricopeptide repeat RAP PF08373.5 CBZ51081.1 - 5.7e-09 35.6 0.0 1.2e-08 34.6 0.0 1.6 1 0 0 1 1 1 1 RAP domain DUF605 PF04652.11 CBZ51081.1 - 1.7 7.9 24.5 3.1 7.1 17.0 1.3 1 0 0 1 1 1 0 Vta1 like Prefoldin_2 PF01920.15 CBZ51082.1 - 1e-08 34.9 7.0 1.3e-08 34.5 4.8 1.2 1 0 0 1 1 1 1 Prefoldin subunit SlyX PF04102.7 CBZ51082.1 - 0.0027 18.0 1.3 0.26 11.7 0.3 2.1 2 0 0 2 2 2 1 SlyX MAD PF05557.8 CBZ51082.1 - 0.0028 15.8 3.6 0.0043 15.2 2.5 1.3 1 0 0 1 1 1 1 Mitotic checkpoint protein STAT_alpha PF01017.15 CBZ51082.1 - 0.0029 17.3 1.4 0.0037 17.0 1.0 1.1 1 0 0 1 1 1 1 STAT protein, all-alpha domain DivIVA PF05103.8 CBZ51082.1 - 0.0042 17.1 5.8 0.0052 16.8 4.1 1.1 1 0 0 1 1 1 1 DivIVA protein ApoLp-III PF07464.6 CBZ51082.1 - 0.0049 16.8 3.7 0.015 15.3 2.4 1.8 1 1 1 2 2 2 1 Apolipophorin-III precursor (apoLp-III) Cluap1 PF10234.4 CBZ51082.1 - 0.0058 15.8 3.5 0.007 15.6 2.4 1.2 1 0 0 1 1 1 1 Clusterin-associated protein-1 Tropomyosin_1 PF12718.2 CBZ51082.1 - 0.0092 15.8 11.7 0.5 10.2 8.3 2.0 1 1 0 1 1 1 1 Tropomyosin like KxDL PF10241.4 CBZ51082.1 - 0.011 15.6 1.1 0.022 14.6 0.1 2.0 2 1 0 2 2 2 0 Uncharacterized conserved protein OmpH PF03938.9 CBZ51082.1 - 0.016 15.1 2.9 0.02 14.8 1.5 1.4 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) Uds1 PF15456.1 CBZ51082.1 - 0.033 14.1 2.6 0.046 13.7 1.8 1.1 1 0 0 1 1 1 0 Up-regulated During Septation Arb1 PF09692.5 CBZ51082.1 - 0.035 12.9 0.3 0.038 12.8 0.2 1.0 1 0 0 1 1 1 0 Argonaute siRNA chaperone (ARC) complex subunit Arb1 AAA_13 PF13166.1 CBZ51082.1 - 0.043 12.2 3.9 0.053 11.9 2.7 1.1 1 0 0 1 1 1 0 AAA domain Syntaxin-6_N PF09177.6 CBZ51082.1 - 0.044 14.1 1.5 4.3 7.7 0.1 2.1 2 0 0 2 2 2 0 Syntaxin 6, N-terminal IZUMO PF15005.1 CBZ51082.1 - 0.057 13.4 0.5 0.083 12.9 0.4 1.2 1 0 0 1 1 1 0 Izumo sperm-egg fusion HemX PF04375.9 CBZ51082.1 - 0.065 11.8 0.3 0.08 11.5 0.2 1.0 1 0 0 1 1 1 0 HemX DUF342 PF03961.8 CBZ51082.1 - 0.075 11.4 3.8 0.087 11.2 2.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Kinetocho_Slk19 PF12709.2 CBZ51082.1 - 0.075 13.1 3.2 1.8 8.7 0.6 2.5 2 1 0 2 2 2 0 Central kinetochore-associated Spc7 PF08317.6 CBZ51082.1 - 0.084 11.5 7.2 0.1 11.2 5.0 1.0 1 0 0 1 1 1 0 Spc7 kinetochore protein Atg14 PF10186.4 CBZ51082.1 - 0.16 10.8 2.3 0.21 10.4 1.6 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Snapin_Pallidin PF14712.1 CBZ51082.1 - 0.2 12.0 4.8 1.4 9.3 3.1 2.1 1 1 1 2 2 2 0 Snapin/Pallidin MerR-DNA-bind PF09278.6 CBZ51082.1 - 0.2 12.0 3.7 8.3 6.8 0.4 2.3 2 0 0 2 2 2 0 MerR, DNA binding NPV_P10 PF05531.7 CBZ51082.1 - 0.35 11.1 3.4 4.5 7.6 0.9 2.2 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF4298 PF14131.1 CBZ51082.1 - 0.44 10.4 2.6 13 5.7 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4298) FliD_N PF02465.13 CBZ51082.1 - 0.44 10.9 2.4 7.9 6.9 0.7 2.2 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 N-terminus V_ATPase_I PF01496.14 CBZ51082.1 - 0.48 8.2 5.7 0.86 7.3 4.0 1.3 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family APG6 PF04111.7 CBZ51082.1 - 0.51 9.3 5.3 0.71 8.8 3.7 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 IncA PF04156.9 CBZ51082.1 - 0.51 9.9 9.5 5 6.6 6.8 1.9 1 1 0 1 1 1 0 IncA protein 3HCDH_N PF02737.13 CBZ51082.1 - 0.55 9.8 3.1 0.71 9.5 2.1 1.3 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain CALCOCO1 PF07888.6 CBZ51082.1 - 0.66 8.2 7.3 3.8 5.7 0.1 2.0 1 1 1 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like DivIC PF04977.10 CBZ51082.1 - 0.68 9.4 8.8 6.3 6.3 0.2 2.4 1 1 1 2 2 2 0 Septum formation initiator AATF-Che1 PF13339.1 CBZ51082.1 - 0.83 9.8 4.4 20 5.3 3.7 1.9 1 1 0 1 1 1 0 Apoptosis antagonizing transcription factor Prefoldin PF02996.12 CBZ51082.1 - 0.98 9.0 10.3 3 7.5 0.1 2.2 1 1 1 2 2 2 0 Prefoldin subunit DUF1664 PF07889.7 CBZ51082.1 - 1.2 8.8 6.4 4.3 7.1 4.4 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) DUF4446 PF14584.1 CBZ51082.1 - 1.3 8.8 5.0 1.8 8.3 1.5 1.9 1 1 0 2 2 2 0 Protein of unknown function (DUF4446) Spc24 PF08286.6 CBZ51082.1 - 1.8 8.3 8.5 9.9 5.8 0.1 2.1 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 DUF4349 PF14257.1 CBZ51082.1 - 2.3 7.3 6.1 7.1 5.7 4.2 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4349) ATG16 PF08614.6 CBZ51082.1 - 2.8 7.7 9.7 6.1 6.6 3.8 2.0 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) DUF4407 PF14362.1 CBZ51083.1 - 7.4 5.4 25.9 16 4.3 18.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Ribosomal_L12 PF00542.14 CBZ51084.1 - 1.1e-19 70.1 8.7 1.9e-19 69.4 3.2 2.3 2 0 0 2 2 2 1 Ribosomal protein L7/L12 C-terminal domain DnaJ PF00226.26 CBZ51085.1 - 2.4e-19 68.8 0.7 5.4e-19 67.6 0.5 1.6 1 0 0 1 1 1 1 DnaJ domain ADH_zinc_N PF00107.21 CBZ51085.1 - 4.5e-05 23.0 0.0 0.082 12.4 0.0 2.5 2 0 0 2 2 2 2 Zinc-binding dehydrogenase ADH_N PF08240.7 CBZ51085.1 - 0.0098 15.6 0.0 0.044 13.5 0.0 2.1 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Abhydrolase_5 PF12695.2 CBZ51085.1 - 0.023 14.4 0.0 0.39 10.4 0.0 2.5 1 1 0 1 1 1 0 Alpha/beta hydrolase family Pro_isomerase PF00160.16 CBZ51086.1 - 3.3e-49 167.0 0.0 3.8e-49 166.8 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD PapD-like PF14874.1 CBZ51087.1 - 8.5e-09 35.2 0.0 1.5e-08 34.4 0.0 1.4 1 0 0 1 1 1 1 Flagellar-associated PapD-like Coa1 PF08695.5 CBZ51087.1 - 0.16 11.4 0.0 0.34 10.4 0.0 1.5 1 0 0 1 1 1 0 Cytochrome oxidase complex assembly protein 1 Atrophin-1 PF03154.10 CBZ51088.1 - 0.0017 16.6 11.4 0.0017 16.6 7.9 2.3 3 0 0 3 3 3 1 Atrophin-1 family U79_P34 PF03064.11 CBZ51088.1 - 0.65 9.4 21.5 2.6 7.4 5.1 2.4 2 0 0 2 2 2 0 HSV U79 / HCMV P34 Vfa1 PF08432.5 CBZ51088.1 - 8.7 6.3 20.3 2.1 8.3 3.5 2.9 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 tRNA-synt_1g PF09334.6 CBZ51090.1 - 1.4e-114 382.7 1.2 2.9e-113 378.4 0.8 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 CBZ51090.1 - 3.4e-37 127.7 2.9 2e-21 75.6 0.0 4.0 2 1 1 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.14 CBZ51090.1 - 2.8e-16 59.5 0.0 1e-08 34.6 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain tRNA-synt_1f PF01921.13 CBZ51090.1 - 1.8e-06 26.8 0.0 0.0013 17.4 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (K) tRNA_bind PF01588.15 CBZ51090.1 - 2.2e-06 27.3 0.1 3.2e-05 23.6 0.0 2.3 2 0 0 2 2 2 1 Putative tRNA binding domain Anticodon_1 PF08264.8 CBZ51090.1 - 0.0058 16.3 0.0 0.014 15.1 0.0 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1d PF00750.14 CBZ51090.1 - 0.021 13.6 0.0 3.1 6.5 0.0 2.2 2 0 0 2 2 2 0 tRNA synthetases class I (R) tRNA-synt_1b PF00579.20 CBZ51090.1 - 0.064 12.3 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 tRNA synthetases class I (W and Y) Cullin PF00888.17 CBZ51091.1 - 2.5e-136 455.6 0.2 6e-135 451.0 0.2 2.1 1 1 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 CBZ51091.1 - 9.2e-27 92.6 1.7 9.2e-27 92.6 1.2 2.3 2 0 0 2 2 2 1 Cullin protein neddylation domain Ribosomal_60s PF00428.14 CBZ51091.1 - 1.7 9.0 10.3 4.8 7.6 1.5 2.8 2 0 0 2 2 2 0 60s Acidic ribosomal protein IFT43 PF15305.1 CBZ51092.1 - 2.3e-23 82.8 0.2 2.8e-23 82.5 0.1 1.0 1 0 0 1 1 1 1 Intraflagellar transport protein 43 Pkinase PF00069.20 CBZ51093.1 - 1.4e-43 148.9 0.0 1.9e-43 148.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ51093.1 - 1.6e-24 86.3 0.0 2e-24 86.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CBZ51093.1 - 2.5e-08 33.9 0.0 0.00066 19.4 0.0 2.2 2 0 0 2 2 2 2 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 CBZ51093.1 - 0.0097 14.7 0.3 0.014 14.2 0.2 1.1 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase ABC1 PF03109.11 CBZ51093.1 - 0.011 15.6 0.0 0.2 11.6 0.0 2.3 1 1 1 2 2 2 0 ABC1 family Kinase-like PF14531.1 CBZ51093.1 - 0.023 13.6 0.1 0.49 9.2 0.0 2.7 3 1 0 3 3 3 0 Kinase-like Kdo PF06293.9 CBZ51093.1 - 0.029 13.4 0.3 0.064 12.3 0.0 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family UCH PF00443.24 CBZ51094.1 - 3.8e-46 157.3 0.0 5.3e-46 156.8 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CBZ51094.1 - 3.5e-18 66.0 0.0 1.6e-10 40.8 0.0 2.2 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase USP7_C2 PF14533.1 CBZ51094.1 - 1.5e-06 27.8 0.0 3.1e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-specific protease C-terminal Mt_ATP-synt_B PF05405.9 CBZ51094.1 - 0.92 8.9 0.2 1.7 8.0 0.1 1.3 1 0 0 1 1 1 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) DUF3505 PF12013.3 CBZ51095.1 - 0.015 15.5 2.4 0.14 12.3 0.2 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3505) Sgf11 PF08209.6 CBZ51095.1 - 0.016 14.5 4.9 0.2 10.9 0.2 2.5 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) ABC2_membrane PF01061.19 CBZ51096.1 - 5.3e-37 127.0 18.7 7.7e-37 126.5 13.0 1.2 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.22 CBZ51096.1 - 4.2e-24 85.3 0.2 1.2e-22 80.6 0.0 2.3 2 0 0 2 2 2 1 ABC transporter ABC2_membrane_3 PF12698.2 CBZ51096.1 - 1.2e-14 54.0 13.6 2e-14 53.4 9.4 1.3 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_21 PF13304.1 CBZ51096.1 - 1.2e-07 32.0 0.0 0.0015 18.5 0.0 2.2 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 CBZ51096.1 - 9.5e-05 21.6 0.2 0.00017 20.7 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 CBZ51096.1 - 0.0032 16.9 0.1 0.0071 15.8 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_28 PF13521.1 CBZ51096.1 - 0.0083 16.0 0.1 0.025 14.5 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 CBZ51096.1 - 0.011 15.6 0.0 0.026 14.5 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain MMR_HSR1 PF01926.18 CBZ51096.1 - 0.012 15.5 0.0 0.024 14.5 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_17 PF13207.1 CBZ51096.1 - 0.027 15.2 0.0 0.058 14.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 CBZ51096.1 - 0.028 14.7 0.0 0.061 13.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 CBZ51096.1 - 0.056 12.8 0.0 0.12 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_15 PF13175.1 CBZ51096.1 - 0.057 12.4 0.0 4.6 6.1 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain PAN_1 PF00024.21 CBZ51098.1 - 4.3e-10 39.2 14.0 3.1e-05 23.6 4.5 2.3 1 1 1 2 2 2 2 PAN domain PAN_4 PF14295.1 CBZ51098.1 - 4e-09 36.0 9.3 0.00018 21.1 2.5 2.6 2 0 0 2 2 2 2 PAN domain PAN_2 PF08276.6 CBZ51098.1 - 0.0013 18.5 14.8 0.06 13.1 3.1 3.3 3 1 1 4 4 4 2 PAN-like domain PAN_3 PF08277.7 CBZ51098.1 - 0.042 13.4 8.9 0.086 12.4 1.3 2.5 2 1 0 2 2 2 0 PAN-like domain SWIRM PF04433.12 CBZ51098.1 - 0.072 13.2 0.0 0.13 12.4 0.0 1.3 1 0 0 1 1 1 0 SWIRM domain DUF605 PF04652.11 CBZ51098.1 - 0.53 9.6 13.6 0.65 9.3 9.4 1.1 1 0 0 1 1 1 0 Vta1 like PAT1 PF09770.4 CBZ51098.1 - 0.98 7.5 14.5 1.2 7.3 10.0 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SpoIIE PF07228.7 CBZ51100.1 - 6.6e-10 39.0 0.2 0.00019 21.1 0.1 2.6 2 0 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.1 CBZ51100.1 - 0.00046 19.6 0.2 0.0042 16.5 0.1 2.1 1 1 0 1 1 1 1 Protein phosphatase 2C Gar1 PF04410.9 CBZ51101.1 - 2.1e-15 56.4 0.0 2.1e-15 56.4 0.0 3.3 3 1 0 3 3 3 1 Gar1/Naf1 RNA binding region Vps8 PF12816.2 CBZ51102.1 - 0.016 14.4 0.1 0.14 11.3 0.0 2.5 2 1 1 3 3 3 0 Golgi CORVET complex core vacuolar protein 8 zf-RING_2 PF13639.1 CBZ51102.1 - 0.13 12.1 0.7 0.33 10.8 0.5 1.7 1 0 0 1 1 1 0 Ring finger domain Clathrin PF00637.15 CBZ51102.1 - 4.4 6.8 0.0 10 5.6 0.0 1.5 1 0 0 1 1 1 0 Region in Clathrin and VPS Ribosomal_L19e PF01280.15 CBZ51103.1 - 2.4e-61 205.8 13.8 2.4e-61 205.8 9.6 1.7 1 1 1 2 2 2 1 Ribosomal protein L19e Sec62 PF03839.11 CBZ51103.1 - 1.6 8.0 10.7 20 4.4 0.0 2.4 2 1 0 2 2 2 0 Translocation protein Sec62 Spc7 PF08317.6 CBZ51104.1 - 0.0001 21.1 2.2 0.0001 21.1 1.5 4.8 4 2 0 4 4 4 2 Spc7 kinetochore protein Reo_sigmaC PF04582.7 CBZ51104.1 - 1.4 7.9 12.7 22 4.0 0.4 4.5 2 1 2 4 4 4 0 Reovirus sigma C capsid protein Filament PF00038.16 CBZ51104.1 - 4.8 6.5 58.8 0.056 12.9 2.7 4.3 3 2 0 4 4 4 0 Intermediate filament protein WD40 PF00400.27 CBZ51105.1 - 1.4e-18 65.9 11.1 1.9e-07 30.6 0.0 6.2 6 0 0 6 6 6 4 WD domain, G-beta repeat BUD22 PF09073.5 CBZ51105.1 - 0.0036 16.4 15.4 0.0036 16.4 10.6 2.1 2 0 0 2 2 2 1 BUD22 Nup160 PF11715.3 CBZ51105.1 - 0.024 12.8 0.0 0.045 11.9 0.0 1.4 1 0 0 1 1 1 0 Nucleoporin Nup120/160 eIF-3c_N PF05470.7 CBZ51105.1 - 0.1 10.6 2.2 0.12 10.4 1.5 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus SDA1 PF05285.7 CBZ51105.1 - 0.7 9.1 23.3 0.2 10.9 13.5 1.8 2 0 0 2 2 2 0 SDA1 Cwf_Cwc_15 PF04889.7 CBZ51105.1 - 0.84 9.3 19.7 1 9.0 10.2 2.2 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Trypan_PARP PF05887.6 CBZ51105.1 - 3.4 7.4 11.4 8.8 6.1 7.9 1.7 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Pox_Ag35 PF03286.9 CBZ51105.1 - 5.5 6.4 15.6 1.3 8.5 6.9 2.2 2 0 0 2 2 2 0 Pox virus Ag35 surface protein RRM_1 PF00076.17 CBZ51106.1 - 1.1e-16 60.2 0.0 1.6e-16 59.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBZ51106.1 - 2.9e-13 49.5 0.0 4.4e-13 48.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBZ51106.1 - 7.6e-09 35.2 0.0 1.5e-08 34.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) IP_trans PF02121.13 CBZ51107.1 - 3.5e-64 216.4 0.4 1.7e-43 148.6 0.0 2.6 3 0 0 3 3 3 2 Phosphatidylinositol transfer protein Oxysterol_BP PF01237.13 CBZ51107.1 - 1.1e-39 135.9 0.0 1.8e-39 135.2 0.0 1.3 1 0 0 1 1 1 1 Oxysterol-binding protein PH PF00169.24 CBZ51107.1 - 5.3e-09 36.2 0.0 9.3e-09 35.4 0.0 1.4 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 CBZ51107.1 - 0.0005 20.2 0.3 0.0023 18.1 0.2 2.1 1 1 0 1 1 1 1 Pleckstrin homology domain Str_synth PF03088.11 CBZ51108.1 - 9e-17 60.8 0.0 2.9e-16 59.2 0.0 1.9 2 0 0 2 2 2 1 Strictosidine synthase SGL PF08450.7 CBZ51108.1 - 2.7e-06 26.9 0.0 2.3e-05 23.9 0.0 2.1 2 0 0 2 2 2 1 SMP-30/Gluconolaconase/LRE-like region Ku_PK_bind PF08785.6 CBZ51109.1 - 0.047 13.6 1.8 0.079 12.8 0.6 1.9 1 1 0 1 1 1 0 Ku C terminal domain like HTH_31 PF13560.1 CBZ51109.1 - 0.049 13.8 4.3 1.4 9.1 1.7 2.7 1 1 0 1 1 1 0 Helix-turn-helix domain HTH_37 PF13744.1 CBZ51109.1 - 0.25 11.1 4.2 0.21 11.3 0.2 2.5 2 1 0 2 2 2 0 Helix-turn-helix domain DNA_topoisoIV PF00521.15 CBZ51109.1 - 1.2 7.9 4.3 1.7 7.3 3.0 1.2 1 0 0 1 1 1 0 DNA gyrase/topoisomerase IV, subunit A HSP20 PF00011.16 CBZ51110.1 - 5.6e-18 64.6 0.0 8.8e-18 64.0 0.0 1.3 1 0 0 1 1 1 1 Hsp20/alpha crystallin family Pox_P21 PF05313.7 CBZ51111.1 - 0.077 12.2 1.3 0.11 11.7 0.9 1.2 1 0 0 1 1 1 0 Poxvirus P21 membrane protein Rad60-SLD_2 PF13881.1 CBZ51111.1 - 0.1 12.5 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Peptidase_C1 PF00112.18 CBZ51112.1 - 1.1e-37 130.0 7.8 1.4e-29 103.5 4.0 2.9 2 1 0 2 2 2 2 Papain family cysteine protease CathepsinC_exc PF08773.6 CBZ51112.1 - 3.1e-05 24.1 0.0 0.044 13.9 0.0 2.6 2 0 0 2 2 2 2 Cathepsin C exclusion domain Peptidase_C1_2 PF03051.10 CBZ51112.1 - 0.00076 18.1 0.3 0.099 11.1 0.1 2.2 2 0 0 2 2 2 2 Peptidase C1-like family Propeptide_C1 PF08127.8 CBZ51112.1 - 0.00084 18.9 0.1 0.0023 17.4 0.0 1.7 1 0 0 1 1 1 1 Peptidase family C1 propeptide GFP PF01353.17 CBZ51112.1 - 0.018 14.4 0.0 0.029 13.7 0.0 1.2 1 0 0 1 1 1 0 Green fluorescent protein SKG6 PF08693.5 CBZ51113.1 - 0.006 15.8 1.0 0.01 15.1 0.7 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain PAN_1 PF00024.21 CBZ51113.1 - 0.14 11.9 1.2 0.33 10.7 0.2 2.1 2 0 0 2 2 2 0 PAN domain DcpS_C PF11969.3 CBZ51114.1 - 8.1e-08 32.5 0.0 1.5e-05 25.1 0.0 2.3 2 0 0 2 2 2 2 Scavenger mRNA decapping enzyme C-term binding PEPCK_ATP PF01293.15 CBZ51115.1 - 4e-215 714.7 0.0 4.7e-215 714.4 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_25 PF13481.1 CBZ51115.1 - 0.021 14.2 0.1 0.054 12.8 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 CBZ51115.1 - 0.026 14.0 0.1 0.058 12.9 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_33 PF13671.1 CBZ51115.1 - 0.045 13.6 0.0 0.078 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain Lactamase_B_2 PF12706.2 CBZ51117.1 - 3.8e-06 26.5 2.5 0.0076 15.8 0.0 2.2 1 1 1 2 2 2 2 Beta-lactamase superfamily domain TIP49 PF06068.8 CBZ51117.1 - 0.0049 15.6 0.0 0.0068 15.1 0.0 1.1 1 0 0 1 1 1 1 TIP49 C-terminus Lactamase_B PF00753.22 CBZ51117.1 - 0.0051 16.4 2.1 0.24 11.0 0.3 2.4 3 0 0 3 3 3 2 Metallo-beta-lactamase superfamily Ras PF00071.17 CBZ51118.1 - 2.2e-62 209.2 0.2 2.6e-62 208.9 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CBZ51118.1 - 7.9e-20 71.5 0.0 1.2e-19 70.9 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CBZ51118.1 - 4.4e-14 52.1 0.1 5.4e-14 51.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 CBZ51118.1 - 2.3e-06 27.5 0.1 6e-06 26.1 0.0 1.8 1 1 1 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 CBZ51118.1 - 1.1e-05 24.9 0.0 1.9e-05 24.2 0.0 1.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 CBZ51118.1 - 6.4e-05 22.2 0.1 0.00013 21.2 0.1 1.5 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_14 PF13173.1 CBZ51118.1 - 0.0015 18.4 0.1 0.0047 16.8 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 CBZ51118.1 - 0.0018 18.4 0.1 0.0052 16.9 0.0 1.9 1 1 1 2 2 2 1 AAA domain DUF258 PF03193.11 CBZ51118.1 - 0.012 14.8 0.1 0.027 13.6 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function, DUF258 SRPRB PF09439.5 CBZ51118.1 - 0.019 14.1 0.0 0.04 13.1 0.0 1.5 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_16 PF13191.1 CBZ51118.1 - 0.079 12.9 0.6 0.33 10.9 0.4 2.2 1 1 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.22 CBZ51118.1 - 0.084 13.1 0.3 0.21 11.8 0.2 1.9 1 1 0 1 1 1 0 ABC transporter AAA_15 PF13175.1 CBZ51118.1 - 0.11 11.5 0.1 0.17 10.9 0.1 1.5 1 1 0 1 1 1 0 AAA ATPase domain Gp_dh_C PF02800.15 CBZ51119.1 - 8.2e-68 226.7 0.0 1.1e-67 226.3 0.0 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.19 CBZ51119.1 - 1e-59 200.8 0.0 3.7e-59 199.0 0.0 1.9 2 0 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain Pep3_Vps18 PF05131.9 CBZ51122.1 - 1e-24 86.6 0.0 1.9e-24 85.7 0.0 1.4 1 0 0 1 1 1 1 Pep3/Vps18/deep orange family Clathrin PF00637.15 CBZ51122.1 - 2.9e-05 23.6 0.0 0.0015 18.1 0.0 2.6 2 0 0 2 2 2 1 Region in Clathrin and VPS Vps39_2 PF10367.4 CBZ51122.1 - 0.00017 21.7 3.7 0.00038 20.6 2.5 1.6 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 DUF3782 PF12644.2 CBZ51122.1 - 0.0061 16.3 0.5 0.24 11.2 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3782) zf-RING_2 PF13639.1 CBZ51122.1 - 0.043 13.6 12.5 0.013 15.2 5.6 2.3 2 0 0 2 2 2 0 Ring finger domain zf-RING_5 PF14634.1 CBZ51122.1 - 1.5 8.6 11.9 0.14 11.8 4.9 1.8 2 0 0 2 2 2 0 zinc-RING finger domain Rdx PF10262.4 CBZ51123.1 - 0.0029 17.6 0.0 0.0037 17.2 0.0 1.3 1 0 0 1 1 1 1 Rdx family BTB PF00651.26 CBZ51124.1 - 0.016 15.2 0.0 0.3 11.0 0.0 2.2 2 0 0 2 2 2 0 BTB/POZ domain ubiquitin PF00240.18 CBZ51125.1 - 3.4e-35 119.2 0.5 4.5e-35 118.8 0.3 1.2 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_L40e PF01020.12 CBZ51125.1 - 2.6e-32 110.1 11.6 4.2e-32 109.5 8.0 1.3 1 0 0 1 1 1 1 Ribosomal L40e family Rad60-SLD PF11976.3 CBZ51125.1 - 1.6e-20 72.5 0.5 2.4e-20 71.9 0.3 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 CBZ51125.1 - 2.6e-06 27.5 0.1 9.2e-06 25.8 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Telomere_Sde2 PF13019.1 CBZ51125.1 - 0.00038 20.1 0.0 0.00054 19.6 0.0 1.2 1 0 0 1 1 1 1 Telomere stability and silencing Rad60-SLD_2 PF13881.1 CBZ51125.1 - 0.0073 16.1 0.0 0.015 15.1 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 CBZ51125.1 - 0.016 15.3 0.0 0.018 15.2 0.0 1.2 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain TUG-UBL1 PF11470.3 CBZ51125.1 - 0.095 12.6 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 GLUT4 regulating protein TUG Fer2_3 PF13085.1 CBZ51125.1 - 0.24 11.2 2.1 1.2 8.9 1.1 2.1 1 1 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain BPL_LplA_LipB PF03099.14 CBZ51126.1 - 2.5e-11 43.6 0.0 5.1e-11 42.6 0.0 1.4 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family BPL_C PF02237.12 CBZ51126.1 - 4.5e-06 26.2 0.7 9.3e-06 25.2 0.5 1.5 1 0 0 1 1 1 1 Biotin protein ligase C terminal domain Adap_comp_sub PF00928.16 CBZ51127.1 - 6.5e-86 287.6 0.0 8e-86 287.3 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 CBZ51127.1 - 7.4e-07 28.9 1.1 1.4e-06 28.1 0.7 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain AAA_2 PF07724.9 CBZ51128.1 - 6.3e-41 140.1 1.9 4e-33 114.7 0.0 3.1 4 0 0 4 4 3 2 AAA domain (Cdc48 subfamily) AAA PF00004.24 CBZ51128.1 - 9.1e-15 55.0 0.1 9e-07 29.1 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.4 CBZ51128.1 - 2.9e-09 36.7 2.1 3.1e-09 36.6 0.1 2.1 2 0 0 2 2 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.9 CBZ51128.1 - 3.4e-08 33.3 0.1 1e-05 25.2 0.0 2.7 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 CBZ51128.1 - 1.1e-07 32.6 0.1 7.6e-07 29.9 0.1 2.5 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 CBZ51128.1 - 1.5e-07 31.6 0.2 6e-07 29.6 0.1 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 CBZ51128.1 - 3.9e-07 30.2 0.3 2.6e-05 24.3 0.0 3.0 3 0 0 3 3 3 1 AAA domain AAA_18 PF13238.1 CBZ51128.1 - 1.3e-05 25.4 0.0 4.2e-05 23.8 0.0 1.9 1 0 0 1 1 1 1 AAA domain MCM PF00493.18 CBZ51128.1 - 2.2e-05 23.4 0.1 0.00088 18.1 0.0 2.2 2 0 0 2 2 2 1 MCM2/3/5 family RuvB_N PF05496.7 CBZ51128.1 - 4.2e-05 22.7 0.3 0.012 14.7 0.0 2.6 2 1 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus Zeta_toxin PF06414.7 CBZ51128.1 - 0.00054 19.1 0.0 0.0012 17.9 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin TIP49 PF06068.8 CBZ51128.1 - 0.00095 17.9 0.2 0.0026 16.5 0.0 1.8 2 0 0 2 2 2 1 TIP49 C-terminus Sigma54_activat PF00158.21 CBZ51128.1 - 0.0016 17.9 0.0 0.022 14.2 0.0 2.3 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_14 PF13173.1 CBZ51128.1 - 0.0044 16.9 0.1 1.2 9.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.16 CBZ51128.1 - 0.0048 16.0 0.2 0.058 12.5 0.0 2.5 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.1 CBZ51128.1 - 0.0079 16.0 0.1 0.025 14.4 0.0 1.9 2 0 0 2 2 1 1 AAA domain IstB_IS21 PF01695.12 CBZ51128.1 - 0.011 15.2 0.0 0.024 14.0 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein T2SE PF00437.15 CBZ51128.1 - 0.016 14.1 0.7 0.023 13.6 0.0 1.6 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_28 PF13521.1 CBZ51128.1 - 0.021 14.8 0.0 0.062 13.2 0.0 1.9 1 0 0 1 1 1 0 AAA domain ResIII PF04851.10 CBZ51128.1 - 0.028 14.2 0.0 0.063 13.0 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit NTPase_1 PF03266.10 CBZ51128.1 - 0.028 14.1 0.3 1.5 8.4 0.0 2.4 2 0 0 2 2 2 0 NTPase IPT PF01745.11 CBZ51128.1 - 0.04 13.0 0.0 0.074 12.2 0.0 1.4 1 0 0 1 1 1 0 Isopentenyl transferase DUF258 PF03193.11 CBZ51128.1 - 0.042 13.0 0.0 0.08 12.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 SKI PF01202.17 CBZ51128.1 - 0.05 13.4 0.5 0.14 12.0 0.0 2.0 2 1 0 2 2 1 0 Shikimate kinase Arch_ATPase PF01637.13 CBZ51128.1 - 0.057 13.1 0.0 2.4 7.8 0.0 2.3 2 0 0 2 2 2 0 Archaeal ATPase AAA_25 PF13481.1 CBZ51128.1 - 0.059 12.7 0.0 5.6 6.3 0.0 2.7 2 1 0 2 2 2 0 AAA domain MobB PF03205.9 CBZ51128.1 - 0.076 12.7 0.0 0.17 11.6 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_3 PF07726.6 CBZ51128.1 - 0.081 12.5 0.0 0.32 10.5 0.0 2.2 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.17 CBZ51128.1 - 0.082 13.0 0.0 0.19 11.8 0.0 1.6 1 0 0 1 1 1 0 RNA helicase NACHT PF05729.7 CBZ51128.1 - 0.086 12.4 0.0 1.8 8.1 0.0 2.6 2 0 0 2 2 2 0 NACHT domain ATP-synt_ab PF00006.20 CBZ51128.1 - 0.089 12.2 0.0 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain Sigma54_activ_2 PF14532.1 CBZ51128.1 - 0.1 12.6 0.0 0.59 10.1 0.0 2.1 2 0 0 2 2 2 0 Sigma-54 interaction domain DEAD PF00270.24 CBZ51128.1 - 0.1 12.0 0.0 1.1 8.6 0.0 2.2 2 0 0 2 2 2 0 DEAD/DEAH box helicase Abhydrolase_6 PF12697.2 CBZ51128.1 - 0.11 12.3 4.3 5.2 6.8 0.4 2.9 1 1 1 2 2 2 0 Alpha/beta hydrolase family EMP24_GP25L PF01105.19 CBZ51130.1 - 1.3e-34 119.5 0.0 1.5e-34 119.3 0.0 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD RabGAP-TBC PF00566.13 CBZ51131.1 - 2.1e-40 138.5 0.0 6.7e-40 136.8 0.0 1.7 1 1 0 1 1 1 1 Rab-GTPase-TBC domain WD40 PF00400.27 CBZ51132.1 - 3.8e-28 96.2 8.0 5.1e-09 35.6 0.0 5.6 6 0 0 6 6 6 5 WD domain, G-beta repeat PQQ_2 PF13360.1 CBZ51132.1 - 0.0005 19.6 0.0 0.0085 15.5 0.0 2.1 1 1 0 1 1 1 1 PQQ-like domain CHCH PF06747.8 CBZ51132.1 - 0.77 9.7 3.0 5 7.1 0.1 3.2 3 0 0 3 3 3 0 CHCH domain DUF485 PF04341.7 CBZ51134.1 - 0.0067 16.1 0.2 0.036 13.7 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function, DUF485 TrbL PF04610.9 CBZ51134.1 - 0.042 13.5 0.8 0.089 12.4 0.6 1.5 1 1 0 1 1 1 0 TrbL/VirB6 plasmid conjugal transfer protein Orbi_NS3 PF01616.11 CBZ51134.1 - 0.097 11.6 0.3 0.17 10.8 0.1 1.5 2 0 0 2 2 2 0 Orbivirus NS3 DUF2178 PF09946.4 CBZ51134.1 - 0.21 11.3 2.2 2.3 8.0 0.3 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2178) DUF4164 PF13747.1 CBZ51134.1 - 0.27 11.3 2.4 0.7 10.0 1.7 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4164) Amnionless PF14828.1 CBZ51134.1 - 0.5 8.8 2.0 4 5.8 0.1 1.9 1 1 1 2 2 2 0 Amnionless DUF900 PF05990.7 CBZ51136.1 - 3.6e-19 69.0 0.0 1.1e-18 67.4 0.0 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF900) TMF_TATA_bd PF12325.3 CBZ51137.1 - 0.13 12.0 1.0 0.32 10.7 0.1 1.9 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF2934 PF11154.3 CBZ51137.1 - 0.18 11.2 1.0 1.6 8.1 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2934) Acetyltransf_1 PF00583.19 CBZ51138.1 - 2.3e-15 56.3 0.1 3.1e-15 55.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 CBZ51138.1 - 8.8e-09 35.5 0.0 1.1e-08 35.2 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 CBZ51138.1 - 2.8e-07 30.6 0.7 3e-07 30.5 0.0 1.4 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 CBZ51138.1 - 1e-06 28.4 0.0 1.4e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_4 PF13420.1 CBZ51138.1 - 2.4e-05 24.3 0.0 2.9e-05 24.0 0.0 1.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 CBZ51138.1 - 0.0015 18.4 0.0 0.0018 18.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 CBZ51138.1 - 0.0064 16.3 0.0 0.01 15.6 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Caenor_Her-1 PF09232.5 CBZ51139.1 - 0.017 15.1 0.1 0.13 12.3 0.0 2.0 2 0 0 2 2 2 0 Caenorhabditis elegans Her-1 PEPCK_ATP PF01293.15 CBZ51141.1 - 2e-128 428.8 0.0 2.5e-128 428.5 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_19 PF13245.1 CBZ51141.1 - 0.062 13.0 0.1 0.34 10.6 0.2 2.0 2 0 0 2 2 2 0 Part of AAA domain zf-HC5HC2H_2 PF13832.1 CBZ51142.1 - 2.6e-57 191.5 25.5 4.9e-27 94.1 2.8 5.2 4 1 0 4 4 4 4 PHD-zinc-finger like domain PHD_2 PF13831.1 CBZ51142.1 - 8.1e-28 95.4 40.6 1.7e-13 49.6 2.8 5.2 4 0 0 4 4 4 3 PHD-finger zf-HC5HC2H PF13771.1 CBZ51142.1 - 2.2e-25 88.6 46.7 2.2e-10 40.5 2.2 5.8 6 0 0 6 6 6 3 PHD-like zinc-binding domain PHD PF00628.24 CBZ51142.1 - 5.5e-06 25.9 93.7 0.00032 20.3 9.7 7.7 8 0 0 8 8 8 5 PHD-finger Actin PF00022.14 CBZ51143.1 - 3e-31 108.2 0.0 5.7e-31 107.3 0.0 1.4 1 0 0 1 1 1 1 Actin Not3 PF04065.10 CBZ51143.1 - 2e-19 69.8 3.0 2e-08 33.8 0.0 3.2 2 1 0 3 3 3 3 Not1 N-terminal domain, CCR4-Not complex component SH3_9 PF14604.1 CBZ51143.1 - 3.9e-05 23.1 0.1 0.00022 20.7 0.0 2.3 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.23 CBZ51143.1 - 4.9e-05 22.6 0.0 0.00012 21.3 0.0 1.7 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 CBZ51143.1 - 5e-05 22.7 0.0 0.0002 20.8 0.0 2.0 1 0 0 1 1 1 1 Variant SH3 domain WD40 PF00400.27 CBZ51144.1 - 2.3e-07 30.4 0.0 0.42 10.5 0.0 5.0 5 0 0 5 5 5 3 WD domain, G-beta repeat IDO PF01231.13 CBZ51144.1 - 2.2 6.6 4.6 3.4 6.0 3.2 1.2 1 0 0 1 1 1 0 Indoleamine 2,3-dioxygenase DUF1767 PF08585.7 CBZ51145.1 - 6e-06 26.4 0.0 1.3e-05 25.4 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1767) IMS PF00817.15 CBZ51146.1 - 2.7e-28 98.6 0.0 3.9e-27 94.8 0.0 2.2 1 1 0 1 1 1 1 impB/mucB/samB family SCP2 PF02036.12 CBZ51147.1 - 5.1e-35 119.8 0.5 3.8e-16 59.2 0.0 2.6 2 0 0 2 2 2 2 SCP-2 sterol transfer family adh_short PF00106.20 CBZ51147.1 - 1.7e-32 112.6 4.8 3.7e-32 111.5 3.3 1.6 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CBZ51147.1 - 9.7e-19 67.7 2.0 1.8e-18 66.8 1.4 1.4 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 CBZ51147.1 - 3e-12 46.8 0.2 7.8e-12 45.4 0.1 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Alkyl_sulf_C PF14864.1 CBZ51147.1 - 7.1e-09 35.7 0.0 0.00042 20.3 0.0 2.6 2 1 0 2 2 2 2 Alkyl sulfatase C-terminal DUF1176 PF06674.6 CBZ51147.1 - 0.084 11.9 1.0 0.2 10.7 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1176) Pol_alpha_B_N PF08418.5 CBZ51148.1 - 0.42 10.0 15.3 0.47 9.9 0.8 3.2 3 0 0 3 3 3 0 DNA polymerase alpha subunit B N-terminal Amino_oxidase PF01593.19 CBZ51149.1 - 5.9e-39 134.3 10.2 3.7e-16 59.2 0.0 4.3 4 0 0 4 4 4 4 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 CBZ51149.1 - 4e-09 36.3 0.8 5.6e-08 32.6 0.8 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 CBZ51149.1 - 0.00011 22.1 0.1 0.00021 21.2 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 CBZ51149.1 - 0.0008 19.7 0.4 0.0016 18.8 0.2 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 CBZ51149.1 - 0.0045 15.5 0.2 0.0067 14.9 0.2 1.2 1 0 0 1 1 1 1 HI0933-like protein Trp_halogenase PF04820.9 CBZ51149.1 - 0.021 13.4 0.6 0.032 12.8 0.4 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Pyr_redox_3 PF13738.1 CBZ51149.1 - 0.071 13.1 0.1 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 CBZ51149.1 - 0.23 10.2 1.3 0.34 9.7 0.9 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Thi4 PF01946.12 CBZ51149.1 - 0.36 9.8 0.0 0.61 9.1 0.0 1.2 1 0 0 1 1 1 0 Thi4 family Mpv17_PMP22 PF04117.7 CBZ51149.1 - 2.6 7.7 0.1 37 4.0 0.1 2.4 2 0 0 2 2 2 0 Mpv17 / PMP22 family Ribosomal_L29e PF01779.12 CBZ51150.1 - 1.7e-24 85.3 15.4 2.5e-24 84.8 10.7 1.2 1 0 0 1 1 1 1 Ribosomal L29e protein family Gemini_AL2 PF01440.11 CBZ51150.1 - 0.16 12.0 4.1 0.17 11.9 2.8 1.0 1 0 0 1 1 1 0 Geminivirus AL2 protein Mg_trans_NIPA PF05653.9 CBZ51151.1 - 3.9e-07 29.3 9.0 1.5e-06 27.3 3.5 2.4 1 1 2 3 3 3 2 Magnesium transporter NIPA EamA PF00892.15 CBZ51151.1 - 3.4e-06 27.1 1.8 3.4e-06 27.1 1.2 3.1 3 1 0 3 3 3 1 EamA-like transporter family RRM_6 PF14259.1 CBZ51152.1 - 3.8e-05 23.5 0.0 0.00092 19.1 0.0 2.8 2 1 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CBZ51152.1 - 0.0013 18.2 0.0 6.2 6.5 0.0 3.7 4 0 0 4 4 4 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBZ51152.1 - 0.086 12.7 0.0 0.23 11.3 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4614 PF15391.1 CBZ51152.1 - 2.9 7.6 8.5 6.5 6.4 5.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) tRNA-synt_2d PF01409.15 CBZ51153.1 - 1.4e-69 234.0 0.1 5.6e-40 137.0 0.0 2.2 1 1 1 2 2 2 2 tRNA synthetases class II core domain (F) HTH_45 PF14947.1 CBZ51153.1 - 0.066 13.0 0.2 6.5 6.6 0.0 2.4 2 0 0 2 2 2 0 Winged helix-turn-helix Met_10 PF02475.11 CBZ51154.1 - 1.4e-20 73.7 0.0 2.2e-20 73.0 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Kelch_4 PF13418.1 CBZ51154.1 - 1.3e-09 37.6 0.3 0.034 13.9 0.0 5.3 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_5 PF13854.1 CBZ51154.1 - 3.3e-09 36.4 0.3 0.017 15.0 0.0 4.5 4 0 0 4 4 4 2 Kelch motif Kelch_6 PF13964.1 CBZ51154.1 - 4.6e-09 36.0 0.0 0.042 14.0 0.0 4.0 3 0 0 3 3 3 3 Kelch motif Kelch_3 PF13415.1 CBZ51154.1 - 2.7e-08 33.7 10.1 0.0019 18.3 0.0 4.6 5 0 0 5 5 4 2 Galactose oxidase, central domain Kelch_1 PF01344.20 CBZ51154.1 - 8.2e-05 22.0 0.0 0.66 9.5 0.0 3.4 3 0 0 3 3 3 2 Kelch motif Methyltransf_26 PF13659.1 CBZ51154.1 - 0.00017 21.5 0.2 0.00048 20.1 0.1 1.7 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 CBZ51154.1 - 0.0016 17.8 0.0 0.0028 17.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.1 CBZ51154.1 - 0.14 11.7 0.0 0.24 10.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain DNA_methylase PF00145.12 CBZ51154.1 - 0.32 10.0 0.0 0.56 9.2 0.0 1.2 1 0 0 1 1 1 0 C-5 cytosine-specific DNA methylase MethyltransfD12 PF02086.10 CBZ51154.1 - 0.51 9.7 0.0 0.8 9.1 0.0 1.2 1 0 0 1 1 1 0 D12 class N6 adenine-specific DNA methyltransferase zf-RanBP PF00641.13 CBZ51155.1 - 2.9e-05 23.0 3.9 2.9e-05 23.0 2.7 1.8 2 0 0 2 2 2 1 Zn-finger in Ran binding protein and others DUF35_N PF12172.3 CBZ51155.1 - 0.0079 16.0 2.7 0.028 14.3 1.8 2.0 1 0 0 1 1 1 1 Rubredoxin-like zinc ribbon domain (DUF35_N) zf-tcix PF14952.1 CBZ51155.1 - 0.036 13.3 5.6 0.11 11.9 3.9 1.8 1 0 0 1 1 1 0 Putative treble-clef, zinc-finger, Zn-binding SAG PF04092.8 CBZ51156.1 - 6.6e-42 142.8 30.5 1.4e-28 99.7 4.4 2.3 2 0 0 2 2 2 2 SRS domain SAG PF04092.8 CBZ51157.1 - 8.1e-44 148.9 26.6 5e-29 101.2 4.6 2.4 2 0 0 2 2 2 2 SRS domain Cu_amine_oxidN1 PF07833.6 CBZ51157.1 - 0.083 13.2 0.1 2.7 8.3 0.0 2.9 3 1 0 3 3 3 0 Copper amine oxidase N-terminal domain SAG PF04092.8 CBZ51158.1 - 2.6e-42 144.1 27.7 4.9e-29 101.2 4.2 2.4 2 0 0 2 2 2 2 SRS domain SAG PF04092.8 CBZ51159.1 - 1.5e-42 144.9 27.6 1e-28 100.1 4.3 2.4 2 0 0 2 2 2 2 SRS domain SAG PF04092.8 CBZ51160.1 - 1.6e-42 144.8 27.6 1e-28 100.1 4.3 2.4 2 0 0 2 2 2 2 SRS domain SAG PF04092.8 CBZ51161.1 - 1.1e-40 138.8 26.5 1.6e-27 96.3 3.7 2.2 2 0 0 2 2 2 2 SRS domain DUF3019 PF11456.3 CBZ51161.1 - 6 7.2 8.4 6.3 7.1 0.3 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3019) SAG PF04092.8 CBZ51162.1 - 8.1e-41 139.2 28.6 1.1e-27 96.8 4.1 2.4 2 0 0 2 2 2 2 SRS domain URO-D PF01208.12 CBZ51163.1 - 1.1e-100 336.9 0.0 1.5e-100 336.4 0.0 1.1 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) Herpes_capsid PF06112.6 CBZ51164.1 - 0.8 9.7 7.1 0.32 11.0 2.2 2.1 2 0 0 2 2 2 0 Gammaherpesvirus capsid protein Hydrolase_6 PF13344.1 CBZ51167.1 - 1.9e-27 95.1 0.0 3.8e-27 94.1 0.0 1.6 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 CBZ51167.1 - 9.8e-15 54.0 0.0 2.9e-14 52.5 0.0 1.8 1 0 0 1 1 1 1 HAD-hyrolase-like HAD_2 PF13419.1 CBZ51167.1 - 3.6e-11 43.5 0.0 3e-05 24.3 0.0 2.6 2 1 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 CBZ51167.1 - 8.2e-10 39.4 0.0 6.6e-09 36.4 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Proteasome PF00227.21 CBZ51170.1 - 5e-36 123.7 0.1 5.9e-36 123.5 0.1 1.0 1 0 0 1 1 1 1 Proteasome subunit Cyclin_N PF00134.18 CBZ51171.1 - 1e-05 25.1 0.0 1.7e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain RecO_C PF02565.10 CBZ51171.1 - 0.1 12.4 1.1 0.2 11.4 0.1 2.0 2 0 0 2 2 2 0 Recombination protein O C terminal GST_C_2 PF13410.1 CBZ51172.1 - 0.1 12.4 1.4 0.35 10.7 0.8 2.0 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain MIF PF01187.13 CBZ51173.1 - 3.2e-17 62.6 0.0 3.5e-17 62.5 0.0 1.0 1 0 0 1 1 1 1 Macrophage migration inhibitory factor (MIF) Tautomerase PF01361.16 CBZ51173.1 - 0.0003 20.3 0.0 0.36 10.4 0.0 2.1 2 0 0 2 2 2 2 Tautomerase enzyme Urb2 PF10441.4 CBZ51173.1 - 0.12 11.9 0.0 0.19 11.3 0.0 1.2 1 0 0 1 1 1 0 Urb2/Npa2 family BNR PF02012.15 CBZ51174.1 - 4.5e-07 28.7 14.7 0.27 11.1 0.3 7.1 7 0 0 7 7 7 3 BNR/Asp-box repeat BNR_2 PF13088.1 CBZ51174.1 - 5.9e-06 25.7 0.1 0.13 11.5 0.0 3.8 1 1 1 2 2 2 2 BNR repeat-like domain BNR_3 PF13859.1 CBZ51174.1 - 5e-05 22.5 0.1 0.016 14.2 0.0 3.5 4 0 0 4 4 4 1 BNR repeat-like domain Kelch_5 PF13854.1 CBZ51175.1 - 6.4e-32 108.9 4.0 5.4e-06 26.2 0.0 6.7 6 0 0 6 6 6 6 Kelch motif Kelch_4 PF13418.1 CBZ51175.1 - 3e-31 106.9 9.5 7.1e-06 25.6 0.0 7.1 7 0 0 7 7 7 5 Galactose oxidase, central domain Metallophos PF00149.23 CBZ51175.1 - 3.6e-30 104.8 0.4 1.2e-29 103.1 0.3 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Kelch_3 PF13415.1 CBZ51175.1 - 3.9e-30 103.3 13.1 3.1e-06 27.1 0.0 8.1 8 0 0 8 8 8 6 Galactose oxidase, central domain Kelch_2 PF07646.10 CBZ51175.1 - 4.3e-21 73.8 12.3 8.6e-07 28.4 0.0 6.6 6 1 1 7 7 7 4 Kelch motif Kelch_6 PF13964.1 CBZ51175.1 - 3e-18 65.1 9.4 0.0047 17.0 0.5 7.0 5 2 2 7 7 7 4 Kelch motif Kelch_1 PF01344.20 CBZ51175.1 - 1.1e-14 53.6 6.6 0.00021 20.7 0.0 6.3 6 0 0 6 6 6 2 Kelch motif RAG2 PF03089.9 CBZ51175.1 - 1.5e-05 23.8 0.1 0.32 9.6 0.0 3.6 4 0 0 4 4 4 2 Recombination activating protein 2 FAP PF07174.6 CBZ51175.1 - 2.7 7.2 20.1 5.6 6.1 13.9 1.5 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) TFIIA PF03153.8 CBZ51175.1 - 2.8 7.7 7.7 4.1 7.2 5.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit AP2 PF00847.15 CBZ51176.1 - 2.5e-07 30.7 0.2 6.2e-07 29.4 0.1 1.7 1 0 0 1 1 1 1 AP2 domain SPT2 PF08243.6 CBZ51177.1 - 1.3e-08 35.1 5.4 1.3e-08 35.1 3.8 3.4 3 0 0 3 3 3 1 SPT2 chromatin protein Octopine_DH PF02317.12 CBZ51178.1 - 2.6e-29 101.8 0.0 3.5e-29 101.4 0.0 1.2 1 0 0 1 1 1 1 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain F420_oxidored PF03807.12 CBZ51178.1 - 0.00022 21.5 0.0 0.00038 20.8 0.0 1.4 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_Gly3P_dh_N PF01210.18 CBZ51178.1 - 0.0023 17.6 0.0 0.0038 16.9 0.0 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus GFO_IDH_MocA PF01408.17 CBZ51178.1 - 0.064 13.7 0.0 0.11 13.0 0.0 1.3 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold Pkinase_Tyr PF07714.12 CBZ51179.1 - 3.1e-08 33.0 0.0 0.01 14.9 0.0 3.1 3 0 0 3 3 3 3 Protein tyrosine kinase Pkinase PF00069.20 CBZ51179.1 - 2e-05 23.8 0.0 0.2 10.7 0.0 2.7 3 0 0 3 3 3 2 Protein kinase domain SAM_2 PF07647.12 CBZ51179.1 - 0.023 14.5 0.0 0.049 13.4 0.0 1.5 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) Tcf25 PF04910.9 CBZ51180.1 - 5e-50 170.4 4.9 1.4e-32 113.0 0.1 3.1 1 1 2 3 3 3 3 Transcriptional repressor TCF25 TPR_12 PF13424.1 CBZ51180.1 - 0.0021 17.9 0.2 0.0083 16.0 0.0 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat PITH PF06201.8 CBZ51181.1 - 2.6e-37 127.9 0.0 3.1e-37 127.6 0.0 1.1 1 0 0 1 1 1 1 PITH domain AAA_33 PF13671.1 CBZ51182.1 - 4e-28 98.0 0.2 6.7e-28 97.3 0.2 1.4 1 0 0 1 1 1 1 AAA domain SPRY PF00622.23 CBZ51182.1 - 2.5e-18 66.3 0.0 4.6e-18 65.4 0.0 1.4 1 0 0 1 1 1 1 SPRY domain Zeta_toxin PF06414.7 CBZ51182.1 - 5.3e-05 22.4 0.0 8.8e-05 21.6 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_18 PF13238.1 CBZ51182.1 - 0.00021 21.6 0.0 0.00039 20.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 CBZ51182.1 - 0.0064 16.2 0.0 0.012 15.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 CBZ51182.1 - 0.019 15.7 0.0 0.033 14.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain KTI12 PF08433.5 CBZ51182.1 - 0.022 13.9 0.0 0.032 13.4 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_16 PF13191.1 CBZ51182.1 - 0.069 13.1 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain Med13_N PF11597.3 CBZ51182.1 - 0.071 11.7 0.5 0.11 11.2 0.4 1.2 1 0 0 1 1 1 0 Mediator complex subunit 13 N-terminal ThiF PF00899.16 CBZ51183.1 - 3.1e-47 159.8 0.2 1.1e-34 119.2 0.0 2.6 2 0 0 2 2 2 2 ThiF family UBACT PF02134.16 CBZ51183.1 - 4.1e-34 115.9 1.8 4.2e-21 74.2 0.1 3.0 2 0 0 2 2 2 2 Repeat in ubiquitin-activating (UBA) protein UBA_e1_C PF09358.5 CBZ51183.1 - 5.3e-31 107.3 0.0 1.1e-30 106.3 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-activating enzyme e1 C-terminal domain UBA_e1_thiolCys PF10585.4 CBZ51183.1 - 8e-20 69.9 4.1 9.8e-20 69.6 1.3 2.3 3 0 0 3 3 3 1 Ubiquitin-activating enzyme active site Tap-RNA_bind PF09162.5 CBZ51183.1 - 0.025 14.1 0.0 0.076 12.5 0.0 1.8 1 0 0 1 1 1 0 Tap, RNA-binding Vps51 PF08700.6 CBZ51185.1 - 8.5e-05 22.3 0.0 0.0002 21.1 0.0 1.6 1 0 0 1 1 1 1 Vps51/Vps67 Voltage_CLC PF00654.15 CBZ51186.1 - 6.5e-73 245.7 25.8 6.5e-73 245.7 17.9 1.9 1 1 1 2 2 2 1 Voltage gated chloride channel CBS PF00571.23 CBZ51186.1 - 0.036 13.8 0.0 1.5 8.6 0.0 2.6 2 0 0 2 2 2 0 CBS domain HEAT_2 PF13646.1 CBZ51187.1 - 7.2e-24 83.8 9.8 3.3e-12 46.4 0.1 4.2 3 1 1 4 4 4 3 HEAT repeats HEAT_PBS PF03130.11 CBZ51187.1 - 1.9e-15 55.6 13.3 0.001 19.3 0.0 7.2 8 0 0 8 8 8 3 PBS lyase HEAT-like repeat HEAT_EZ PF13513.1 CBZ51187.1 - 1.4e-05 25.3 9.4 0.32 11.5 0.0 5.4 5 1 1 6 6 6 2 HEAT-like repeat HEAT PF02985.17 CBZ51187.1 - 5.4e-05 22.9 0.6 1.6 9.0 0.0 5.0 6 0 0 6 6 6 2 HEAT repeat Arm PF00514.18 CBZ51187.1 - 0.00025 20.7 0.5 0.93 9.4 0.0 3.1 3 0 0 3 3 3 2 Armadillo/beta-catenin-like repeat UPF0147 PF03685.8 CBZ51187.1 - 0.06 13.2 0.4 0.62 9.9 0.0 2.7 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0147) RuvA_C PF07499.8 CBZ51187.1 - 0.14 12.3 2.5 0.4 10.8 0.0 3.0 3 0 0 3 3 3 0 RuvA, C-terminal domain LOH1CR12 PF10158.4 CBZ51189.1 - 0.018 14.7 0.0 0.026 14.3 0.0 1.4 1 0 0 1 1 1 0 Tumour suppressor protein ABC2_membrane PF01061.19 CBZ51190.1 - 1.7e-28 99.2 21.9 1.7e-28 99.2 15.2 2.1 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.22 CBZ51190.1 - 2.3e-22 79.7 0.0 4.6e-22 78.8 0.0 1.5 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.2 CBZ51190.1 - 1.6e-08 33.9 18.5 2.4e-08 33.4 12.8 1.2 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_21 PF13304.1 CBZ51190.1 - 5.3e-08 33.1 0.0 7.1e-05 22.9 0.0 2.3 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 CBZ51190.1 - 0.00012 21.3 0.1 0.00023 20.3 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 CBZ51190.1 - 0.004 17.1 0.0 0.01 15.8 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.1 CBZ51190.1 - 0.012 15.1 0.1 0.025 14.0 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_25 PF13481.1 CBZ51190.1 - 0.028 13.7 0.0 0.22 10.8 0.0 2.3 3 0 0 3 3 3 0 AAA domain AAA_17 PF13207.1 CBZ51190.1 - 0.04 14.7 0.1 0.13 13.0 0.0 1.9 2 0 0 2 2 1 0 AAA domain AAA_28 PF13521.1 CBZ51190.1 - 0.057 13.3 0.2 0.12 12.2 0.0 1.7 2 0 0 2 2 1 0 AAA domain cobW PF02492.14 CBZ51190.1 - 0.08 12.3 0.2 0.15 11.4 0.2 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain MMR_HSR1 PF01926.18 CBZ51190.1 - 0.088 12.7 0.0 0.18 11.7 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase UPF0079 PF02367.12 CBZ51190.1 - 0.11 12.0 0.1 0.23 11.1 0.1 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 PduV-EutP PF10662.4 CBZ51190.1 - 0.11 11.9 0.1 0.27 10.7 0.1 1.6 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_18 PF13238.1 CBZ51190.1 - 0.14 12.5 0.0 0.29 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.1 CBZ51190.1 - 0.36 11.1 0.0 0.64 10.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain NTP_transf_2 PF01909.18 CBZ51191.1 - 0.0043 17.3 0.0 0.0095 16.2 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain PAP_central PF04928.12 CBZ51191.1 - 0.019 13.8 0.6 0.031 13.0 0.1 1.5 2 0 0 2 2 2 0 Poly(A) polymerase central domain WGG PF10273.4 CBZ51191.1 - 0.045 13.8 0.0 0.24 11.5 0.0 2.3 1 1 0 1 1 1 0 Pre-rRNA-processing protein TSR2 CoA_binding PF02629.14 CBZ51192.1 - 6.7e-25 87.4 0.0 1.9e-24 85.9 0.0 1.8 1 0 0 1 1 1 1 CoA binding domain Ligase_CoA PF00549.14 CBZ51192.1 - 1e-24 86.8 0.2 1.6e-24 86.2 0.2 1.3 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.1 CBZ51192.1 - 9.4e-06 25.2 0.0 1.9e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.1 CBZ51192.1 - 0.001 19.1 0.1 0.006 16.7 0.0 2.3 3 0 0 3 3 3 1 CoA binding domain SseB PF07179.7 CBZ51192.1 - 0.069 12.9 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 SseB protein N-terminal domain AP2 PF00847.15 CBZ51195.1 - 7e-10 38.9 0.8 1.6e-09 37.8 0.5 1.6 1 0 0 1 1 1 1 AP2 domain MutS_V PF00488.16 CBZ51196.1 - 3.7e-82 275.2 0.0 5.2e-82 274.7 0.0 1.2 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 CBZ51196.1 - 7.3e-40 136.9 0.5 2.2e-39 135.3 0.3 1.9 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.15 CBZ51196.1 - 1.6e-31 108.6 0.0 3.3e-31 107.6 0.0 1.6 1 0 0 1 1 1 1 MutS domain I AAA_29 PF13555.1 CBZ51196.1 - 0.069 12.6 0.0 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain PPR_3 PF13812.1 CBZ51197.1 - 0.1 12.9 0.4 4.3 7.8 0.0 3.3 2 0 0 2 2 2 0 Pentatricopeptide repeat domain RRM_5 PF13893.1 CBZ51198.1 - 5.5e-34 115.8 0.4 5e-12 45.4 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CBZ51198.1 - 3.5e-27 93.8 0.1 1.1e-08 34.5 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBZ51198.1 - 7.5e-27 93.1 0.1 9e-11 41.6 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 CBZ51198.1 - 0.0076 15.9 0.0 2.2 8.1 0.0 2.8 3 1 0 3 3 3 2 Limkain b1 RRM_3 PF08777.6 CBZ51198.1 - 0.011 15.6 0.0 0.78 9.6 0.0 2.7 3 0 0 3 3 3 0 RNA binding motif Peptidase_M17 PF00883.16 CBZ51199.1 - 3.2e-119 397.4 2.0 4.2e-119 397.0 1.4 1.1 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain Peptidase_M17_N PF02789.12 CBZ51199.1 - 9.1e-07 28.6 0.6 2.5e-06 27.2 0.0 2.1 2 0 0 2 2 2 1 Cytosol aminopeptidase family, N-terminal domain F-protein PF00469.15 CBZ51201.1 - 0.0014 18.0 0.2 0.0035 16.7 0.0 1.7 1 1 0 1 1 1 1 Negative factor, (F-Protein) or Nef Dicty_REP PF05086.7 CBZ51201.1 - 0.0081 13.9 6.4 0.013 13.3 4.4 1.2 1 0 0 1 1 1 1 Dictyostelium (Slime Mold) REP protein Mucin PF01456.12 CBZ51201.1 - 0.015 15.0 14.0 0.015 15.0 9.7 2.3 2 0 0 2 2 2 0 Mucin-like glycoprotein V_ATPase_I PF01496.14 CBZ51202.1 - 4.8e-149 497.6 0.0 5.3e-144 480.9 0.0 2.8 2 1 0 2 2 2 2 V-type ATPase 116kDa subunit family CS PF04969.11 CBZ51203.1 - 3.3e-06 27.5 0.1 3.8e-05 24.1 0.1 2.2 1 1 0 1 1 1 1 CS domain Trypsin_2 PF13365.1 CBZ51204.1 - 2.1e-14 53.5 0.3 4.1e-14 52.6 0.2 1.5 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.21 CBZ51204.1 - 3.1e-14 53.1 0.1 5.7e-14 52.2 0.1 1.4 1 0 0 1 1 1 1 Trypsin PDZ_2 PF13180.1 CBZ51204.1 - 3.3e-05 23.6 1.1 0.00018 21.2 0.4 2.2 2 0 0 2 2 2 1 PDZ domain Peptidase_S46 PF10459.4 CBZ51204.1 - 0.098 11.0 0.3 1.4 7.2 0.1 2.2 2 0 0 2 2 2 0 Peptidase S46 PDZ PF00595.19 CBZ51204.1 - 0.11 12.6 0.1 0.51 10.5 0.0 2.0 2 0 0 2 2 2 0 PDZ domain (Also known as DHR or GLGF) Ribosomal_60s PF00428.14 CBZ51204.1 - 0.28 11.6 4.6 66 4.0 0.0 2.5 2 0 0 2 2 2 0 60s Acidic ribosomal protein WD40 PF00400.27 CBZ51205.1 - 6.9e-37 124.0 8.1 3.2e-09 36.3 0.0 6.6 6 0 0 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.3 CBZ51205.1 - 2.4e-08 32.5 0.9 0.00021 19.5 0.2 2.5 1 1 1 2 2 2 2 Nucleoporin Nup120/160 PQQ_2 PF13360.1 CBZ51205.1 - 0.0022 17.5 0.1 0.55 9.6 0.0 2.7 1 1 2 3 3 3 2 PQQ-like domain LisH PF08513.6 CBZ51205.1 - 0.05 13.3 0.0 0.1 12.4 0.0 1.5 1 0 0 1 1 1 0 LisH PQQ_3 PF13570.1 CBZ51205.1 - 0.2 11.9 1.4 5.9 7.3 0.0 3.2 4 0 0 4 4 4 0 PQQ-like domain MFS_1 PF07690.11 CBZ51206.1 - 2.3e-08 33.1 30.2 7.3e-05 21.6 1.1 2.9 2 1 1 3 3 3 2 Major Facilitator Superfamily Patched PF02460.13 CBZ51207.1 - 3.7e-93 312.9 4.9 9.3e-49 166.0 6.9 2.0 2 0 0 2 2 2 2 Patched family Sterol-sensing PF12349.3 CBZ51207.1 - 5e-30 103.9 0.2 5e-30 103.9 0.1 2.6 3 0 0 3 3 3 2 Sterol-sensing domain of SREBP cleavage-activation SKI PF01202.17 CBZ51207.1 - 0.036 13.9 0.1 0.074 12.9 0.0 1.5 1 0 0 1 1 1 0 Shikimate kinase ACR_tran PF00873.14 CBZ51207.1 - 3.5 4.8 20.2 6.5 4.0 12.5 2.3 3 0 0 3 3 3 0 AcrB/AcrD/AcrF family DnaJ PF00226.26 CBZ51208.1 - 2.8e-16 59.0 0.1 4.7e-16 58.2 0.1 1.4 1 0 0 1 1 1 1 DnaJ domain adh_short PF00106.20 CBZ51209.1 - 7.8e-20 71.4 0.0 1.5e-19 70.5 0.0 1.4 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 CBZ51209.1 - 2.8e-07 30.3 0.0 7.1e-07 29.0 0.0 1.6 1 1 1 2 2 2 1 KR domain adh_short_C2 PF13561.1 CBZ51209.1 - 2.4e-06 27.5 0.0 3.3e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NUDIX PF00293.23 CBZ51210.1 - 1.8e-05 24.4 0.0 2.4e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain 2OG-FeII_Oxy_3 PF13640.1 CBZ51212.1 - 1.6e-08 34.9 0.0 4.4e-08 33.5 0.0 1.8 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 CBZ51212.1 - 4.9e-08 33.1 0.0 9.7e-08 32.2 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 CBZ51212.1 - 0.0033 17.0 0.0 0.007 15.9 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Mnd1 PF03962.10 CBZ51213.1 - 5.5e-35 120.7 4.0 7e-35 120.3 2.8 1.1 1 0 0 1 1 1 1 Mnd1 family TBPIP PF07106.8 CBZ51213.1 - 0.0091 15.5 5.5 0.011 15.2 3.6 1.3 1 1 0 1 1 1 1 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF848 PF05852.6 CBZ51213.1 - 0.065 13.0 3.6 0.065 13.0 1.9 1.4 1 1 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) EMP70 PF02990.11 CBZ51214.1 - 1.9e-155 518.3 17.0 1.9e-151 505.1 11.2 2.1 1 1 1 2 2 2 2 Endomembrane protein 70 Clathrin PF00637.15 CBZ51215.1 - 5.5e-181 593.3 25.8 1.8e-31 108.6 0.1 7.5 7 0 0 7 7 7 7 Region in Clathrin and VPS Clathrin_H_link PF13838.1 CBZ51215.1 - 4.4e-27 93.7 3.3 6.1e-27 93.2 0.3 2.9 3 0 0 3 3 3 1 Clathrin-H-link Clathrin_propel PF01394.15 CBZ51215.1 - 2.6e-06 27.3 0.0 0.0034 17.5 0.0 4.0 4 0 0 4 4 4 1 Clathrin propeller repeat Coatomer_WDAD PF04053.9 CBZ51215.1 - 9.3e-06 24.6 1.9 0.087 11.6 0.1 3.4 4 0 0 4 4 4 2 Coatomer WD associated region TPR_2 PF07719.12 CBZ51215.1 - 0.15 12.0 0.0 0.15 12.0 0.0 6.0 7 1 2 9 9 9 0 Tetratricopeptide repeat TPR_1 PF00515.23 CBZ51215.1 - 0.55 9.9 0.0 0.55 9.9 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat PPDK_N PF01326.14 CBZ51216.1 - 7.1e-47 160.0 0.9 1.2e-46 159.2 0.1 1.8 2 0 0 2 2 2 1 Pyruvate phosphate dikinase, PEP/pyruvate binding domain CBM_20 PF00686.14 CBZ51216.1 - 9.2e-19 66.8 0.1 1.6e-18 66.0 0.1 1.4 1 0 0 1 1 1 1 Starch binding domain Aminotran_1_2 PF00155.16 CBZ51217.1 - 6.7e-38 130.5 0.0 2.7e-37 128.5 0.0 1.9 2 0 0 2 2 2 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 CBZ51217.1 - 6.3e-06 24.7 0.0 1.1e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme OKR_DC_1 PF01276.15 CBZ51217.1 - 0.0054 15.3 0.0 0.067 11.7 0.0 2.0 1 1 0 1 1 1 1 Orn/Lys/Arg decarboxylase, major domain Aminotran_1_2 PF00155.16 CBZ51218.1 - 3e-42 144.8 0.0 5e-42 144.1 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 CBZ51218.1 - 6.5e-05 21.3 0.0 0.00012 20.4 0.0 1.4 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme OKR_DC_1 PF01276.15 CBZ51218.1 - 0.0026 16.3 0.0 0.027 13.0 0.0 2.0 1 1 0 1 1 1 1 Orn/Lys/Arg decarboxylase, major domain zf-HC5HC2H_2 PF13832.1 CBZ51220.1 - 2.8e-17 62.6 4.2 2.8e-17 62.6 2.9 3.1 2 1 1 3 3 3 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 CBZ51220.1 - 3.1e-16 59.3 0.2 3.1e-16 59.3 0.1 3.5 3 2 0 3 3 3 1 PHD-like zinc-binding domain PHD PF00628.24 CBZ51220.1 - 3.6e-09 36.1 25.1 9.2e-07 28.4 4.5 4.1 4 0 0 4 4 4 3 PHD-finger PHD_2 PF13831.1 CBZ51220.1 - 5.4e-09 35.2 6.7 5.4e-09 35.2 4.7 3.4 4 0 0 4 4 4 1 PHD-finger Dpy-30 PF05186.8 CBZ51220.1 - 0.068 12.6 0.0 0.19 11.2 0.0 1.8 1 0 0 1 1 1 0 Dpy-30 motif Skp1_POZ PF03931.10 CBZ51221.1 - 3e-07 30.4 0.0 7.1e-07 29.2 0.0 1.6 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain SR-25 PF10500.4 CBZ51221.1 - 0.001 18.6 19.3 0.0015 18.0 13.3 1.3 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Lin-8 PF03353.10 CBZ51221.1 - 0.23 10.7 3.4 0.31 10.2 2.4 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist DUF4614 PF15391.1 CBZ51221.1 - 0.28 10.9 10.1 0.39 10.4 7.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) Sporozoite_P67 PF05642.6 CBZ51221.1 - 0.32 8.8 10.9 0.47 8.2 7.6 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Pap_E4 PF02711.9 CBZ51221.1 - 1 10.2 5.9 1.3 9.8 3.5 1.6 1 1 0 1 1 1 0 E4 protein Apt1 PF10351.4 CBZ51221.1 - 3.7 6.2 8.9 4.5 6.0 6.2 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain CytochromB561_N PF09786.4 CBZ51221.1 - 3.8 5.8 10.7 4.6 5.5 7.4 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal Macoilin PF09726.4 CBZ51221.1 - 6.5 4.8 15.1 7.5 4.6 10.4 1.1 1 0 0 1 1 1 0 Transmembrane protein Myosin_head PF00063.16 CBZ51222.1 - 2.5e-27 95.2 0.0 3e-20 71.8 0.0 3.2 3 0 0 3 3 3 3 Myosin head (motor domain) RCC1 PF00415.13 CBZ51222.1 - 4e-24 84.5 19.8 5.8e-07 29.6 0.0 7.8 7 1 0 7 7 7 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 CBZ51222.1 - 7.9e-06 25.3 32.2 0.0065 16.0 1.8 7.0 6 1 0 6 6 6 3 Regulator of chromosome condensation (RCC1) repeat IQ PF00612.22 CBZ51222.1 - 0.00032 20.0 51.5 0.0077 15.7 0.7 7.3 7 0 0 7 7 7 4 IQ calmodulin-binding motif zf-RING_2 PF13639.1 CBZ51223.1 - 3.8e-12 45.8 10.4 7.2e-12 44.9 7.2 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 CBZ51223.1 - 7.8e-07 29.0 8.9 1.7e-06 27.9 6.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 CBZ51223.1 - 2.4e-06 27.5 8.6 5.4e-06 26.4 5.9 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 CBZ51223.1 - 2.6e-06 26.9 5.2 5e-06 26.0 3.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBZ51223.1 - 9.6e-05 22.0 6.7 0.00019 21.1 4.7 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 CBZ51223.1 - 0.0022 17.6 9.4 0.0043 16.6 6.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_1 PF14446.1 CBZ51223.1 - 0.013 15.2 3.8 0.025 14.3 2.6 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 zf-Apc11 PF12861.2 CBZ51223.1 - 0.023 14.5 4.5 0.062 13.1 3.1 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 CBZ51223.1 - 0.17 11.6 5.6 0.38 10.5 3.9 1.6 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_4 PF14570.1 CBZ51223.1 - 0.47 10.0 4.8 0.94 9.1 3.3 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Ldh_1_N PF00056.18 CBZ51224.1 - 1.3e-34 119.0 0.2 2.3e-34 118.2 0.1 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 CBZ51224.1 - 2.5e-34 118.5 0.0 3.6e-34 117.9 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Glyco_hydro_4 PF02056.11 CBZ51224.1 - 0.0026 17.1 1.4 0.0038 16.5 0.2 1.8 2 0 0 2 2 2 1 Family 4 glycosyl hydrolase 3Beta_HSD PF01073.14 CBZ51224.1 - 0.062 11.9 0.0 0.1 11.3 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family UDPG_MGDP_dh_N PF03721.9 CBZ51224.1 - 0.21 10.9 1.9 0.5 9.7 1.3 1.7 1 1 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Pkinase PF00069.20 CBZ51225.1 - 2e-76 256.5 0.0 2.7e-76 256.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ51225.1 - 8.8e-43 146.2 0.0 1.3e-42 145.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 CBZ51225.1 - 0.00028 20.0 0.2 0.00067 18.7 0.1 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 CBZ51225.1 - 0.0013 17.7 0.0 0.0019 17.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 CBZ51225.1 - 0.0018 18.0 0.4 0.01 15.5 0.1 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 CBZ51225.1 - 0.0031 17.0 0.1 0.0051 16.4 0.1 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase YukC PF10140.4 CBZ51225.1 - 0.0054 15.3 0.1 0.0075 14.8 0.1 1.1 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukC DUF3373 PF11853.3 CBZ51226.1 - 0.012 14.2 4.5 0.017 13.6 3.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) RcsC PF09456.5 CBZ51226.1 - 0.043 13.4 0.2 0.48 10.1 0.1 2.2 2 0 0 2 2 2 0 RcsC Alpha-Beta-Loop (ABL) V_ATPase_I PF01496.14 CBZ51226.1 - 0.25 9.1 2.9 0.41 8.4 2.0 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Atg14 PF10186.4 CBZ51226.1 - 0.76 8.6 5.2 1.4 7.7 3.6 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 TBP PF00352.16 CBZ51227.1 - 1.6e-34 117.1 0.0 3.6e-15 55.1 0.0 3.1 3 0 0 3 3 3 3 Transcription factor TFIID (or TATA-binding protein, TBP) SNF2_N PF00176.18 CBZ51228.1 - 5.6e-46 156.6 0.0 1.1e-45 155.7 0.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain HDA2-3 PF11496.3 CBZ51228.1 - 0.00016 20.6 0.0 0.0055 15.5 0.0 2.2 2 0 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 Helicase_C PF00271.26 CBZ51228.1 - 0.00077 19.2 0.0 0.002 17.9 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF917 PF06032.7 CBZ51228.1 - 0.39 9.2 0.0 0.85 8.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF917) PRTP PF01366.13 CBZ51228.1 - 0.78 7.6 3.3 1.6 6.6 2.3 1.4 1 0 0 1 1 1 0 Herpesvirus processing and transport protein Mon1 PF03164.9 CBZ51229.1 - 1.1e-70 238.3 0.5 9.6e-36 123.2 0.0 2.1 2 0 0 2 2 2 2 Trafficking protein Mon1 WT1 PF02165.10 CBZ51230.1 - 0.12 11.4 0.0 0.19 10.7 0.0 1.2 1 0 0 1 1 1 0 Wilm's tumour protein Not1 PF04054.10 CBZ51231.1 - 7.5e-128 426.5 1.1 1.4e-126 422.4 0.8 2.3 1 1 0 1 1 1 1 CCR4-Not complex component, Not1 DUF3819 PF12842.2 CBZ51231.1 - 4.3e-55 185.4 4.3 7.1e-55 184.7 3.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3819) Adeno_52K PF03052.10 CBZ51232.1 - 0.93 8.6 6.3 0.19 10.9 0.5 2.0 2 0 0 2 2 2 0 Adenoviral protein L1 52/55-kDa Dynein_light PF01221.13 CBZ51234.1 - 7.1e-19 67.5 0.0 8.9e-19 67.2 0.0 1.1 1 0 0 1 1 1 1 Dynein light chain type 1 Chorein_N PF12624.2 CBZ51235.1 - 2.1e-33 114.3 0.0 4.3e-33 113.3 0.0 1.5 1 0 0 1 1 1 1 N-terminal region of Chorein, a TM vesicle-mediated sorter DUF1162 PF06650.7 CBZ51235.1 - 5e-05 22.6 0.0 0.00011 21.4 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1162) ATG_C PF09333.6 CBZ51235.1 - 0.01 15.9 0.1 0.12 12.5 0.0 2.5 2 0 0 2 2 2 0 ATG C terminal domain PMI_typeI PF01238.16 CBZ51235.1 - 5.4 5.8 0.1 8.8 5.1 0.0 1.2 1 0 0 1 1 1 0 Phosphomannose isomerase type I Rer1 PF03248.8 CBZ51236.1 - 3e-60 202.8 7.3 4.1e-60 202.3 5.1 1.1 1 0 0 1 1 1 1 Rer1 family DUF2208 PF09973.4 CBZ51236.1 - 6.2 5.9 11.5 0.13 11.5 3.2 1.6 2 0 0 2 2 2 0 Predicted membrane protein (DUF2208) ATP-synt_C PF00137.16 CBZ51237.1 - 2e-32 110.8 21.5 1.6e-16 59.9 2.5 2.1 2 0 0 2 2 2 2 ATP synthase subunit C Oxidored_q2 PF00420.19 CBZ51237.1 - 0.12 11.9 2.5 0.61 9.7 0.8 2.6 1 1 0 1 1 1 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L ABC2_membrane_4 PF12730.2 CBZ51237.1 - 0.93 8.6 7.3 0.083 12.0 0.3 2.3 3 0 0 3 3 3 0 ABC-2 family transporter protein MatE PF01554.13 CBZ51237.1 - 5.4 6.6 12.1 0.097 12.2 2.7 1.9 2 1 0 2 2 2 0 MatE RIC3 PF15361.1 CBZ51238.1 - 0.09 13.0 0.0 0.17 12.0 0.0 1.5 1 0 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 RRM_1 PF00076.17 CBZ51239.1 - 5.3e-13 48.4 0.0 8.6e-13 47.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBZ51239.1 - 2.5e-05 24.1 0.0 4.7e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF2360 PF10152.4 CBZ51241.1 - 5.3 7.3 5.6 59 3.9 0.2 3.4 3 0 0 3 3 3 0 Predicted coiled-coil domain-containing protein (DUF2360) zf-MYND PF01753.13 CBZ51242.1 - 5.4e-05 22.9 0.6 5.4e-05 22.9 0.4 1.9 2 0 0 2 2 2 1 MYND finger zf-Mss51 PF13824.1 CBZ51242.1 - 0.022 14.6 0.6 0.052 13.4 0.4 1.6 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 OmpH PF03938.9 CBZ51242.1 - 0.039 13.9 11.2 0.39 10.6 4.8 2.6 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Atg14 PF10186.4 CBZ51242.1 - 5.5 5.8 8.4 11 4.8 5.8 1.4 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 GILT PF03227.11 CBZ51243.1 - 1.9e-19 69.4 0.0 5.4e-19 68.0 0.0 1.7 2 0 0 2 2 2 1 Gamma interferon inducible lysosomal thiol reductase (GILT) APP_N PF02177.11 CBZ51243.1 - 0.12 12.3 0.6 0.23 11.3 0.4 1.4 1 0 0 1 1 1 0 Amyloid A4 N-terminal heparin-binding DUF1635 PF07795.6 CBZ51244.1 - 0.00048 19.5 1.1 0.00048 19.5 0.8 3.7 5 0 0 5 5 5 1 Protein of unknown function (DUF1635) Peptidase_C50 PF03568.12 CBZ51245.1 - 0.012 14.3 0.0 0.014 14.0 0.0 1.1 1 0 0 1 1 1 0 Peptidase family C50 FliT PF05400.8 CBZ51245.1 - 1.3 9.4 7.3 16 6.0 1.9 2.9 1 1 1 2 2 2 0 Flagellar protein FliT OTCace_N PF02729.16 CBZ51246.1 - 2.1e-34 118.2 0.0 3.1e-34 117.6 0.0 1.4 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain OTCace PF00185.19 CBZ51246.1 - 6.1e-22 78.1 0.1 5.4e-13 49.1 0.1 2.3 1 1 1 2 2 2 2 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain MGDG_synth PF06925.6 CBZ51247.1 - 0.018 14.9 0.1 0.04 13.8 0.0 1.5 1 0 0 1 1 1 0 Monogalactosyldiacylglycerol (MGDG) synthase DUF3896 PF13035.1 CBZ51248.1 - 0.28 11.2 8.1 0.59 10.2 0.3 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3896) LepA_C PF06421.7 CBZ51248.1 - 0.96 9.3 6.2 0.82 9.6 3.2 1.8 1 1 0 2 2 2 0 GTP-binding protein LepA C-terminus TSC22 PF01166.13 CBZ51248.1 - 1.2 9.1 11.3 8.1 6.4 0.0 4.0 4 1 0 4 4 4 0 TSC-22/dip/bun family APG6 PF04111.7 CBZ51248.1 - 2.7 6.9 30.0 1.9 7.4 5.3 2.3 1 1 0 2 2 2 0 Autophagy protein Apg6 ERM PF00769.14 CBZ51248.1 - 5.1 6.5 31.8 0.35 10.3 7.7 2.3 1 1 1 2 2 2 0 Ezrin/radixin/moesin family Helicase_C PF00271.26 CBZ51249.1 - 7.4e-15 54.5 0.0 1.4e-14 53.6 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 CBZ51249.1 - 2.5e-14 53.1 0.0 1.2e-12 47.6 0.0 2.1 2 0 0 2 2 2 2 DEAD/DEAH box helicase Sec23_trunk PF04811.10 CBZ51250.1 - 6.2e-59 199.3 0.0 8.6e-59 198.8 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 CBZ51250.1 - 2.4e-31 107.2 1.1 5.2e-31 106.1 0.7 1.6 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 CBZ51250.1 - 5.5e-30 103.7 0.0 1e-29 102.8 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 CBZ51250.1 - 3.8e-14 51.9 4.4 7.7e-14 50.9 3.1 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 CBZ51250.1 - 7.5e-13 47.9 0.1 2.4e-12 46.3 0.0 1.8 1 1 0 1 1 1 1 Gelsolin repeat MutS_IV PF05190.13 CBZ51250.1 - 0.2 11.8 0.2 0.69 10.1 0.0 2.0 2 0 0 2 2 2 0 MutS family domain IV Arf PF00025.16 CBZ51252.1 - 7.8e-30 103.3 0.0 9.4e-30 103.1 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 CBZ51252.1 - 0.00084 18.7 0.0 0.0011 18.4 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.5 CBZ51252.1 - 0.0015 17.8 0.0 0.015 14.5 0.0 2.0 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Miro PF08477.8 CBZ51252.1 - 0.015 15.7 0.0 0.024 15.1 0.0 1.5 1 0 0 1 1 1 0 Miro-like protein Usp PF00582.21 CBZ51252.1 - 0.023 14.8 0.0 0.031 14.4 0.0 1.2 1 0 0 1 1 1 0 Universal stress protein family Gtr1_RagA PF04670.7 CBZ51252.1 - 0.15 11.1 0.0 0.21 10.7 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Thioredoxin PF00085.15 CBZ51253.1 - 1.3e-07 31.1 0.2 2.4e-07 30.3 0.0 1.5 2 0 0 2 2 2 1 Thioredoxin AAA_12 PF13087.1 CBZ51254.1 - 3.8e-58 196.1 0.0 7.6e-58 195.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain UPF1_Zn_bind PF09416.5 CBZ51254.1 - 2.4e-56 189.5 5.4 3.8e-56 188.9 3.8 1.3 1 0 0 1 1 1 1 RNA helicase (UPF2 interacting domain) AAA_11 PF13086.1 CBZ51254.1 - 2.9e-53 180.8 0.0 4.3e-53 180.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 CBZ51254.1 - 1.8e-11 43.6 0.0 1.8e-11 43.6 0.0 3.3 3 0 0 3 3 2 1 Part of AAA domain AAA_30 PF13604.1 CBZ51254.1 - 2.6e-11 43.4 0.1 7.8e-09 35.3 0.0 3.4 2 1 0 2 2 2 1 AAA domain DEAD PF00270.24 CBZ51254.1 - 3.7e-05 23.2 0.2 0.00059 19.3 0.0 2.7 2 1 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.10 CBZ51254.1 - 0.00018 21.3 0.0 0.00033 20.5 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF2075 PF09848.4 CBZ51254.1 - 0.0041 16.1 0.8 0.017 14.1 0.0 2.2 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_25 PF13481.1 CBZ51254.1 - 0.016 14.6 0.0 0.038 13.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain PhoH PF02562.11 CBZ51254.1 - 0.019 14.1 0.0 0.048 12.8 0.0 1.7 1 0 0 1 1 1 0 PhoH-like protein Ribosomal_S13_N PF08069.7 CBZ51254.1 - 0.056 13.2 0.1 0.17 11.7 0.1 1.8 1 0 0 1 1 1 0 Ribosomal S13/S15 N-terminal domain UvrD-helicase PF00580.16 CBZ51254.1 - 0.1 11.8 0.0 0.21 10.8 0.0 1.6 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain AAA PF00004.24 CBZ51254.1 - 0.2 11.8 0.0 0.43 10.7 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) SNF2_N PF00176.18 CBZ51254.1 - 0.25 10.1 0.0 0.42 9.3 0.0 1.2 1 0 0 1 1 1 0 SNF2 family N-terminal domain EF-hand_like PF09279.6 CBZ51255.1 - 0.023 14.7 0.5 8.8 6.4 0.0 3.0 2 0 0 2 2 2 0 Phosphoinositide-specific phospholipase C, efhand-like DUF2884 PF11101.3 CBZ51255.1 - 0.05 12.9 4.1 2.8 7.2 0.4 3.3 3 1 0 3 3 3 0 Protein of unknown function (DUF2884) CagZ PF09053.5 CBZ51255.1 - 0.066 12.5 0.2 1.4 8.2 0.0 2.6 3 0 0 3 3 3 0 CagZ Baculo_PEP_C PF04513.7 CBZ51255.1 - 0.18 11.6 4.7 17 5.2 0.1 4.1 4 0 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Exonuc_VII_L PF02601.10 CBZ51256.1 - 0.23 10.6 6.6 0.27 10.3 4.6 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit ATG_C PF09333.6 CBZ51256.1 - 0.28 11.3 1.9 1.1 9.3 0.2 2.5 1 1 1 2 2 2 0 ATG C terminal domain DUF1664 PF07889.7 CBZ51256.1 - 0.56 10.0 6.2 0.51 10.1 3.3 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Fzo_mitofusin PF04799.8 CBZ51256.1 - 1.1 8.6 6.3 1.2 8.5 3.4 1.6 1 1 1 2 2 2 0 fzo-like conserved region Ribosomal_S30 PF04758.9 CBZ51257.1 - 1.3e-27 95.3 11.7 1.4e-27 95.1 8.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S30 Endosulfine PF04667.12 CBZ51257.1 - 0.094 12.6 1.3 0.12 12.3 0.9 1.1 1 0 0 1 1 1 0 cAMP-regulated phosphoprotein/endosulfine conserved region TgMIC1 PF11476.3 CBZ51259.1 - 8.1e-79 261.8 2.0 1.2e-78 261.3 1.4 1.2 1 0 0 1 1 1 1 Toxoplasma gondii micronemal protein 1 TgMIC1 MAR_sialic_bdg PF10564.4 CBZ51259.1 - 2.3e-37 126.7 6.4 5.5e-27 93.4 1.1 2.9 3 0 0 3 3 3 2 Sialic-acid binding micronemal adhesive repeat Metallothio_PEC PF02068.11 CBZ51259.1 - 0.46 10.8 12.5 0.075 13.4 0.7 3.0 2 1 0 2 2 2 0 Plant PEC family metallothionein RNase_H2-Ydr279 PF09468.5 CBZ51260.1 - 6e-14 51.9 0.5 2.7e-13 49.8 0.0 2.0 2 0 0 2 2 2 1 Ydr279p protein family (RNase H2 complex component) CcmD PF04995.9 CBZ51261.1 - 0.087 12.5 0.5 0.087 12.5 0.4 3.4 4 1 0 4 4 4 0 Heme exporter protein D (CcmD) DUF2723 PF11028.3 CBZ51261.1 - 0.09 12.2 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2723) Neurensin PF14927.1 CBZ51261.1 - 0.12 11.8 0.0 0.32 10.3 0.0 1.8 2 0 0 2 2 2 0 Neurensin DUF202 PF02656.10 CBZ51261.1 - 0.25 11.5 1.7 1.7 8.9 0.2 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF202) CobD_Cbib PF03186.8 CBZ51261.1 - 0.28 10.2 2.0 0.37 9.8 0.1 2.1 2 1 1 3 3 3 0 CobD/Cbib protein RRM_1 PF00076.17 CBZ51262.1 - 9.1e-40 134.1 0.3 3.8e-19 68.0 0.1 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBZ51262.1 - 5.3e-35 119.2 0.0 6.4e-17 61.2 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBZ51262.1 - 5.6e-26 90.1 0.1 3.8e-12 45.8 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 CBZ51262.1 - 2.3e-05 24.0 0.0 0.01 15.6 0.0 2.4 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif MatE PF01554.13 CBZ51263.1 - 0.13 11.9 29.8 0.22 11.1 3.9 4.8 4 1 1 5 5 5 0 MatE RRM_1 PF00076.17 CBZ51264.1 - 7.2e-23 80.0 0.0 1.4e-13 50.2 0.0 3.7 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBZ51264.1 - 5.4e-11 42.3 0.0 2.9e-06 27.1 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBZ51264.1 - 5e-08 32.6 0.0 0.053 13.3 0.0 3.5 3 1 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF566 PF04484.7 CBZ51264.1 - 6 6.2 5.5 10 5.5 3.8 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF566) Ribosomal_L13 PF00572.13 CBZ51265.1 - 4.7e-25 88.1 1.8 5.5e-25 87.8 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein L13 Pkinase PF00069.20 CBZ51266.1 - 8.3e-58 195.5 0.0 1.1e-57 195.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ51266.1 - 6.5e-37 127.0 0.0 8.9e-37 126.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBZ51266.1 - 0.005 15.8 0.0 0.0082 15.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like PARG_cat PF05028.9 CBZ51267.1 - 0.11 11.7 0.0 0.11 11.6 0.0 1.0 1 0 0 1 1 1 0 Poly (ADP-ribose) glycohydrolase (PARG) Rtf2 PF04641.7 CBZ51268.1 - 5.8e-51 173.1 1.1 9e-51 172.5 0.7 1.3 1 0 0 1 1 1 1 Rtf2 RING-finger zf-RING_UBOX PF13445.1 CBZ51268.1 - 0.0015 18.1 0.1 0.0015 18.1 0.1 2.5 3 0 0 3 3 3 1 RING-type zinc-finger Ank_2 PF12796.2 CBZ51269.1 - 5.1e-33 113.2 0.0 1.1e-17 64.1 0.0 3.6 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.1 CBZ51269.1 - 4.9e-21 74.6 0.0 1.6e-08 34.8 0.0 4.5 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.25 CBZ51269.1 - 1e-18 66.1 0.2 2.5e-08 33.3 0.0 4.9 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.1 CBZ51269.1 - 6.8e-16 56.7 0.0 4.4e-05 23.3 0.0 5.2 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.1 CBZ51269.1 - 4.3e-15 55.4 1.7 9.9e-06 25.6 0.0 5.3 4 1 1 5 5 5 4 Ankyrin repeats (many copies) TPR_16 PF13432.1 CBZ51269.1 - 0.00015 22.3 1.2 0.0013 19.3 0.8 2.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_19 PF14559.1 CBZ51269.1 - 0.0021 18.3 2.2 0.007 16.6 1.2 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 CBZ51269.1 - 0.033 14.1 1.9 5 7.1 0.2 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.1 CBZ51269.1 - 0.051 13.2 0.3 0.2 11.3 0.2 2.0 1 0 0 1 1 1 0 TPR repeat DUF605 PF04652.11 CBZ51269.1 - 4.1 6.6 9.5 7 5.9 6.6 1.3 1 0 0 1 1 1 0 Vta1 like Fcf1 PF04900.7 CBZ51270.1 - 1.8e-17 63.2 0.3 1.8e-06 27.9 0.0 3.6 3 0 0 3 3 3 3 Fcf1 RRM_6 PF14259.1 CBZ51271.1 - 2e-31 107.7 0.0 4.4e-12 45.7 0.0 3.6 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CBZ51271.1 - 9.5e-31 105.2 0.0 6.5e-13 48.1 0.0 3.7 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBZ51271.1 - 4.8e-10 39.1 0.0 0.00017 21.3 0.0 3.2 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PCI PF01399.22 CBZ51272.1 - 2.5e-20 72.7 0.1 1.1e-19 70.6 0.0 2.2 2 0 0 2 2 2 1 PCI domain Rpn3_C PF08375.6 CBZ51272.1 - 1.7e-19 69.9 2.3 4e-19 68.7 1.6 1.6 1 0 0 1 1 1 1 Proteasome regulatory subunit C-terminal PCI_Csn8 PF10075.4 CBZ51272.1 - 0.018 14.8 0.0 0.07 12.8 0.0 2.0 2 0 0 2 2 2 0 COP9 signalosome, subunit CSN8 DUF605 PF04652.11 CBZ51273.1 - 1.4 8.2 25.7 0.033 13.5 5.8 2.7 2 0 0 2 2 2 0 Vta1 like zf-C3HC4_3 PF13920.1 CBZ51273.1 - 2.8 7.6 35.3 0.011 15.4 10.0 4.1 4 0 0 4 4 4 0 Zinc finger, C3HC4 type (RING finger) SAG PF04092.8 CBZ51274.1 - 7.8e-43 145.8 20.4 2.1e-25 89.5 2.5 2.1 2 0 0 2 2 2 2 SRS domain SAG PF04092.8 CBZ51275.1 - 2.9e-46 156.8 15.5 4.4e-27 94.9 3.8 2.2 2 0 0 2 2 2 2 SRS domain Njmu-R1 PF15053.1 CBZ51275.1 - 0.011 14.4 0.1 0.088 11.5 0.0 1.9 2 0 0 2 2 2 0 Mjmu-R1-like protein family SAG PF04092.8 CBZ51276.1 - 1.1e-47 161.5 18.9 3.6e-28 98.4 5.5 2.1 2 0 0 2 2 2 2 SRS domain Njmu-R1 PF15053.1 CBZ51276.1 - 0.025 13.3 0.0 0.038 12.7 0.0 1.2 1 0 0 1 1 1 0 Mjmu-R1-like protein family SAG PF04092.8 CBZ51277.1 - 8.4e-46 155.3 24.8 2.3e-27 95.8 3.1 2.2 2 0 0 2 2 2 2 SRS domain SAG PF04092.8 CBZ51278.1 - 1.6e-48 164.1 18.6 4.4e-27 94.9 3.8 2.2 2 0 0 2 2 2 2 SRS domain Njmu-R1 PF15053.1 CBZ51278.1 - 0.064 12.0 0.0 0.11 11.2 0.0 1.3 1 0 0 1 1 1 0 Mjmu-R1-like protein family SAG PF04092.8 CBZ51279.1 - 3.5e-44 150.1 17.6 1.7e-27 96.2 3.9 2.1 2 0 0 2 2 2 2 SRS domain Tad_C PF09977.4 CBZ51279.1 - 0.034 15.1 0.2 2.8 9.0 0.0 2.8 2 1 0 2 2 2 0 Putative Tad-like Flp pilus-assembly SAG PF04092.8 CBZ51280.1 - 2.9e-44 150.4 22.0 1.1e-27 96.8 2.7 2.2 2 0 0 2 2 2 2 SRS domain SAG PF04092.8 CBZ51281.1 - 1.8e-47 160.7 22.0 1.1e-28 100.1 4.3 2.2 2 0 0 2 2 2 2 SRS domain Njmu-R1 PF15053.1 CBZ51281.1 - 0.0062 15.3 0.5 0.24 10.1 0.0 2.1 2 0 0 2 2 2 2 Mjmu-R1-like protein family Levi_coat PF01819.12 CBZ51281.1 - 0.02 14.4 1.4 1.5 8.4 0.1 2.3 2 0 0 2 2 2 0 Levivirus coat protein SAG PF04092.8 CBZ51282.1 - 1e-43 148.6 18.1 1.2e-28 99.9 2.1 2.2 2 0 0 2 2 2 2 SRS domain SAG PF04092.8 CBZ51283.1 - 3.7e-46 156.5 15.0 1.6e-28 99.5 2.8 2.3 2 1 0 2 2 2 2 SRS domain S4 PF01479.20 CBZ51285.1 - 6.7e-05 22.2 0.0 0.00012 21.3 0.0 1.5 1 0 0 1 1 1 1 S4 domain NAD_Gly3P_dh_N PF01210.18 CBZ51288.1 - 1.4e-45 154.8 0.0 2.8e-45 153.8 0.0 1.5 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.9 CBZ51288.1 - 2e-42 144.3 0.4 3.7e-42 143.5 0.0 1.6 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus Sigma70_r1_1 PF03979.9 CBZ51288.1 - 0.033 14.1 0.2 9.9 6.1 0.0 2.7 2 0 0 2 2 2 0 Sigma-70 factor, region 1.1 EzrA PF06160.7 CBZ51288.1 - 0.21 9.7 6.5 0.3 9.2 4.5 1.2 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA FlxA PF14282.1 CBZ51288.1 - 3.9 7.4 18.7 1.1 9.2 7.8 2.2 2 0 0 2 2 2 0 FlxA-like protein Pkinase PF00069.20 CBZ51290.1 - 1.2e-34 119.6 0.0 2.6e-17 62.8 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ51290.1 - 2.7e-18 65.9 0.0 2.9e-08 33.1 0.0 2.4 2 1 0 2 2 2 2 Protein tyrosine kinase OST-HTH PF12872.2 CBZ51291.1 - 0.031 14.0 0.0 0.074 12.8 0.0 1.5 1 0 0 1 1 1 0 OST-HTH/LOTUS domain zf-C3HC4_2 PF13923.1 CBZ51291.1 - 0.036 14.0 4.5 0.095 12.7 3.1 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 CBZ51291.1 - 0.28 10.9 3.6 0.59 9.8 2.5 1.5 1 0 0 1 1 1 0 RING-type zinc-finger DOT1 PF08123.8 CBZ51292.1 - 2.4e-06 27.0 0.0 3.9e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Histone methylation protein DOT1 PrmA PF06325.8 CBZ51292.1 - 0.3 10.1 0.0 0.5 9.4 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) SAG PF04092.8 CBZ51293.1 - 1.7e-19 70.4 7.5 4.4e-12 46.4 4.3 2.3 2 0 0 2 2 2 2 SRS domain UPF0150 PF03681.10 CBZ51293.1 - 0.15 11.6 0.1 2.9 7.5 0.0 2.5 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0150) SAG PF04092.8 CBZ51294.1 - 6.8e-18 65.2 2.5 1.3e-07 32.0 2.4 2.2 2 0 0 2 2 2 2 SRS domain Abhydrolase_5 PF12695.2 CBZ51295.1 - 3.5e-13 49.5 1.8 1.5e-11 44.2 1.2 2.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF818 PF05677.7 CBZ51295.1 - 0.038 12.7 0.0 0.073 11.7 0.0 1.3 1 0 0 1 1 1 0 Chlamydia CHLPS protein (DUF818) DUF1043 PF06295.7 CBZ51295.1 - 0.99 9.0 0.6 1.9 8.1 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) DEAD PF00270.24 CBZ51296.1 - 5.4e-42 143.1 0.0 6.5e-41 139.6 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CBZ51296.1 - 1.9e-26 91.7 0.0 5.7e-26 90.1 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 CBZ51296.1 - 0.00015 21.6 0.0 0.008 16.0 0.0 2.5 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C_2 PF13307.1 CBZ51296.1 - 0.0015 18.5 0.1 1.2 9.0 0.0 3.2 3 0 0 3 3 3 1 Helicase C-terminal domain SecA_DEAD PF07517.9 CBZ51296.1 - 0.015 14.6 2.0 0.039 13.2 1.4 1.8 1 1 0 1 1 1 0 SecA DEAD-like domain zf-CCHC PF00098.18 CBZ51296.1 - 0.018 14.9 2.8 0.018 14.9 2.0 2.0 2 0 0 2 2 2 0 Zinc knuckle Solute_trans_a PF03619.11 CBZ51298.1 - 5.2e-55 186.6 9.2 4.1e-54 183.7 6.4 2.2 1 1 0 1 1 1 1 Organic solute transporter Ostalpha WD40 PF00400.27 CBZ51299.1 - 1.5e-15 56.4 12.5 6e-07 29.1 0.2 4.8 5 0 0 5 5 5 3 WD domain, G-beta repeat HMG_box PF00505.14 CBZ51301.1 - 2.3e-24 85.4 2.4 3.2e-24 84.9 1.7 1.2 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 CBZ51301.1 - 4e-19 68.7 1.8 5.5e-19 68.3 1.2 1.2 1 0 0 1 1 1 1 HMG-box domain HMG_box_5 PF14887.1 CBZ51301.1 - 0.012 15.3 1.3 0.025 14.3 0.8 1.6 1 1 0 1 1 1 0 HMG (high mobility group) box 5 KIAA1430 PF13879.1 CBZ51301.1 - 0.031 14.6 0.2 0.042 14.2 0.1 1.2 1 0 0 1 1 1 0 KIAA1430 homologue Microtub_assoc PF07989.6 CBZ51301.1 - 0.082 12.7 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 Microtubule associated DUF4191 PF13829.1 CBZ51302.1 - 0.008 15.3 0.7 0.014 14.5 0.5 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4191) DUF1182 PF06681.8 CBZ51302.1 - 0.022 13.9 1.8 0.022 13.9 1.2 1.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1182) YtpI PF14007.1 CBZ51302.1 - 0.7 9.8 6.1 0.33 10.8 1.6 2.0 2 0 0 2 2 2 0 YtpI-like protein DUF2231 PF09990.4 CBZ51302.1 - 0.98 9.7 6.4 5.5 7.3 2.5 2.1 1 1 1 2 2 2 0 Predicted membrane protein (DUF2231) zf-DHHC PF01529.15 CBZ51302.1 - 1.4 8.3 7.5 4.4 6.6 5.2 1.8 1 1 0 1 1 1 0 DHHC palmitoyltransferase DUF3995 PF13160.1 CBZ51302.1 - 1.6 8.7 9.8 0.85 9.6 3.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3995) DUF2975 PF11188.3 CBZ51302.1 - 1.9 8.2 7.8 2.5 7.8 2.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2975) Lamp PF01299.12 CBZ51303.1 - 0.025 13.7 0.2 0.038 13.1 0.1 1.2 1 0 0 1 1 1 0 Lysosome-associated membrane glycoprotein (Lamp) DnaJ PF00226.26 CBZ51304.1 - 3.3e-11 42.7 0.0 1.2e-10 40.9 0.0 2.0 1 0 0 1 1 1 1 DnaJ domain Ank_5 PF13857.1 CBZ51304.1 - 0.076 13.2 0.0 0.22 11.8 0.0 1.8 1 0 0 1 1 1 0 Ankyrin repeats (many copies) PAP_assoc PF03828.14 CBZ51305.1 - 1.9e-05 24.5 0.0 4.1e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 CBZ51305.1 - 3.3e-05 24.1 0.0 0.00013 22.2 0.0 2.0 1 1 0 1 1 1 1 Nucleotidyltransferase domain DUF2561 PF10812.3 CBZ51306.1 - 0.011 15.3 0.5 0.019 14.5 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2561) MbeD_MobD PF04899.7 CBZ51306.1 - 0.02 14.8 1.8 0.054 13.4 0.2 2.5 2 0 0 2 2 2 0 MbeD/MobD like DUF4486 PF14858.1 CBZ51307.1 - 2.5e-10 39.2 2.1 3.9e-10 38.6 1.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4486) TAN PF11640.3 CBZ51307.1 - 0.45 10.2 0.0 5.4 6.7 0.0 2.2 2 0 0 2 2 2 0 Telomere-length maintenance and DNA damage repair DUF3359 PF11839.3 CBZ51309.1 - 0.86 9.9 9.2 0.27 11.5 2.6 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3359) zf-RING_2 PF13639.1 CBZ51311.1 - 3e-10 39.7 5.2 5.7e-10 38.8 3.6 1.5 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 CBZ51311.1 - 7e-09 35.6 2.9 1.3e-08 34.8 2.0 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 CBZ51311.1 - 5.9e-07 29.0 4.8 1e-06 28.2 3.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 CBZ51311.1 - 5.4e-06 26.1 1.4 1.3e-05 24.9 0.9 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.1 CBZ51311.1 - 0.00027 20.9 6.3 0.0005 20.0 4.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBZ51311.1 - 0.00031 20.3 5.0 0.00061 19.4 3.5 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 CBZ51311.1 - 0.00059 19.4 3.4 0.0012 18.4 2.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_1 PF14446.1 CBZ51311.1 - 0.003 17.2 1.1 0.003 17.2 0.8 2.0 2 0 0 2 2 2 1 Prokaryotic RING finger family 1 zf-RING-like PF08746.6 CBZ51311.1 - 0.005 16.8 2.5 0.0097 15.8 1.7 1.4 1 0 0 1 1 1 1 RING-like domain RINGv PF12906.2 CBZ51311.1 - 0.18 11.8 4.9 0.35 10.9 3.4 1.5 1 0 0 1 1 1 0 RING-variant domain PHD PF00628.24 CBZ51311.1 - 1.2 8.8 4.0 2.1 8.0 2.8 1.4 1 0 0 1 1 1 0 PHD-finger Ribosomal_L32p PF01783.18 CBZ51311.1 - 3.9 7.7 6.5 9 6.5 1.8 2.7 2 0 0 2 2 2 0 Ribosomal L32p protein family TGT PF01702.13 CBZ51313.1 - 1.7e-16 60.2 0.0 2.1e-09 36.9 0.1 2.2 2 0 0 2 2 2 2 Queuine tRNA-ribosyltransferase NAD_kinase PF01513.16 CBZ51314.1 - 1.6e-05 23.8 0.0 0.053 12.3 0.0 2.2 2 0 0 2 2 2 2 ATP-NAD kinase DAGK_cat PF00781.19 CBZ51314.1 - 0.0025 17.2 0.0 0.0056 16.1 0.0 1.5 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain RNA_pol_Rbc25 PF08292.7 CBZ51315.1 - 2.9e-26 92.0 0.0 4.6e-26 91.4 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.12 CBZ51315.1 - 4.6e-11 42.6 0.0 7.1e-11 42.0 0.0 1.3 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 SAG PF04092.8 CBZ51316.1 - 7.9e-43 145.7 20.4 1.5e-26 93.2 1.3 2.4 2 1 0 2 2 2 2 SRS domain Njmu-R1 PF15053.1 CBZ51316.1 - 0.026 13.2 0.4 0.048 12.3 0.0 1.5 2 0 0 2 2 2 0 Mjmu-R1-like protein family Tweety PF04906.8 CBZ51316.1 - 4 5.7 6.7 0.78 8.0 0.4 2.0 2 0 0 2 2 2 0 Tweety SAG PF04092.8 CBZ51317.1 - 4.3e-47 159.5 20.8 6.1e-27 94.4 3.4 2.1 2 0 0 2 2 2 2 SRS domain PepSY_TM_2 PF13703.1 CBZ51317.1 - 0.019 15.1 0.2 8.1 6.7 0.1 2.3 2 0 0 2 2 2 0 PepSY-associated TM helix SAG PF04092.8 CBZ51318.1 - 2.1e-44 150.8 18.0 7.5e-28 97.4 3.6 2.1 2 0 0 2 2 2 2 SRS domain Njmu-R1 PF15053.1 CBZ51318.1 - 0.015 14.0 0.4 0.87 8.2 0.0 2.1 2 0 0 2 2 2 0 Mjmu-R1-like protein family Ig_2 PF13895.1 CBZ51318.1 - 0.16 12.1 3.6 0.22 11.6 1.2 2.3 2 0 0 2 2 2 0 Immunoglobulin domain SAG PF04092.8 CBZ51319.1 - 1.1e-43 148.5 19.3 8.1e-28 97.2 4.8 2.2 2 0 0 2 2 2 2 SRS domain SAG PF04092.8 CBZ51320.1 - 5.8e-37 126.8 1.2 3.1e-26 92.2 0.1 2.0 2 0 0 2 2 2 2 SRS domain SAG PF04092.8 CBZ51321.1 - 4.4e-43 146.6 21.8 7.8e-29 100.5 4.1 2.3 2 0 0 2 2 2 2 SRS domain Njmu-R1 PF15053.1 CBZ51321.1 - 0.066 11.9 0.0 0.1 11.3 0.0 1.2 1 0 0 1 1 1 0 Mjmu-R1-like protein family SAG PF04092.8 CBZ51322.1 - 3.9e-18 66.0 0.5 5.4e-18 65.5 0.3 1.2 1 0 0 1 1 1 1 SRS domain vATP-synt_E PF01991.13 CBZ51324.1 - 8.6e-58 194.8 0.9 1.1e-57 194.5 0.6 1.1 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit DUF4239 PF14023.1 CBZ51324.1 - 0.00025 20.4 5.8 0.00034 20.0 3.6 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF4239) DUF1800 PF08811.6 CBZ51324.1 - 0.055 12.3 5.3 0.073 11.9 3.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1800) Spidroin_MaSp PF11260.3 CBZ51324.1 - 0.088 12.8 0.7 0.25 11.4 0.3 1.9 2 0 0 2 2 2 0 Major ampullate spidroin 1 and 2 CDC37_N PF03234.9 CBZ51324.1 - 0.1 12.8 7.1 0.11 12.8 4.4 1.5 1 1 0 1 1 1 0 Cdc37 N terminal kinase binding CRISPR_Cse2 PF09485.5 CBZ51324.1 - 0.16 12.0 1.7 0.24 11.4 1.1 1.4 1 0 0 1 1 1 0 CRISPR-associated protein Cse2 (CRISPR_cse2) DUF445 PF04286.7 CBZ51324.1 - 1.4 8.3 8.7 2.1 7.7 6.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF445) DUF848 PF05852.6 CBZ51324.1 - 3.2 7.6 10.7 2.8 7.7 5.1 2.0 1 1 1 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) ERCC4 PF02732.10 CBZ51325.1 - 8.2e-15 54.8 0.0 4.6e-14 52.3 0.0 2.3 2 0 0 2 2 2 1 ERCC4 domain MSP1_C PF07462.6 CBZ51325.1 - 1.4 7.1 5.3 2.7 6.2 3.7 1.4 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus mRNA_cap_enzyme PF01331.14 CBZ51326.1 - 1.4e-39 135.7 0.0 1.4e-38 132.5 0.0 2.1 1 1 0 1 1 1 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.10 CBZ51326.1 - 9.6e-05 22.6 0.0 0.009 16.3 0.0 2.8 2 0 0 2 2 2 1 mRNA capping enzyme, C-terminal domain HET PF06985.6 CBZ51326.1 - 0.00044 20.4 0.1 0.0069 16.5 0.0 2.3 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) Cyclin PF08613.6 CBZ51327.1 - 4.2e-33 114.8 0.2 6.8e-33 114.1 0.1 1.3 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 CBZ51327.1 - 8.3e-09 35.0 0.1 1.4e-08 34.3 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain DUF2217 PF10265.4 CBZ51327.1 - 0.1 11.3 0.1 0.17 10.6 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) Kelch_3 PF13415.1 CBZ51328.1 - 2.8e-20 71.9 7.3 0.0001 22.3 0.1 6.4 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_5 PF13854.1 CBZ51328.1 - 3.9e-18 64.9 0.2 0.0042 16.9 0.0 6.1 6 0 0 6 6 6 4 Kelch motif Kelch_4 PF13418.1 CBZ51328.1 - 7.7e-17 60.8 8.1 0.00098 18.8 0.0 6.1 5 0 0 5 5 5 5 Galactose oxidase, central domain HATPase_c_3 PF13589.1 CBZ51328.1 - 1.4e-09 37.6 0.0 2.9e-09 36.7 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Kelch_6 PF13964.1 CBZ51328.1 - 3.4e-06 26.9 0.2 0.016 15.4 0.0 4.1 4 0 0 4 4 4 2 Kelch motif Kelch_1 PF01344.20 CBZ51328.1 - 1.5e-05 24.4 0.0 0.28 10.7 0.0 4.0 4 0 0 4 4 4 2 Kelch motif HATPase_c PF02518.21 CBZ51328.1 - 0.00058 19.5 0.0 0.0012 18.5 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Acetyltransf_1 PF00583.19 CBZ51329.1 - 4.5e-12 45.8 0.0 8.1e-12 45.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 CBZ51329.1 - 0.00047 20.2 0.0 0.0008 19.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 CBZ51329.1 - 0.00063 19.6 0.0 0.0015 18.4 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 CBZ51329.1 - 0.0023 17.8 0.0 0.02 14.8 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 CBZ51329.1 - 0.0031 17.6 0.0 0.0063 16.6 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 CBZ51329.1 - 0.008 16.0 0.0 0.029 14.2 0.0 1.9 2 0 0 2 2 2 1 GCN5-related N-acetyl-transferase NR_Repeat PF14046.1 CBZ51329.1 - 0.025 14.3 0.1 0.1 12.3 0.0 2.1 1 1 0 1 1 1 0 Nuclear receptor repeat Peptidase_M24 PF00557.19 CBZ51330.1 - 1.7e-37 129.0 0.1 3.2e-37 128.1 0.0 1.5 2 0 0 2 2 2 1 Metallopeptidase family M24 Myc_N PF01056.13 CBZ51330.1 - 0.17 10.9 7.8 0.16 11.1 4.5 1.5 2 0 0 2 2 2 0 Myc amino-terminal region TATR PF03430.8 CBZ51330.1 - 8.5 4.8 5.1 11 4.5 3.6 1.1 1 0 0 1 1 1 0 Trans-activating transcriptional regulator SRP-alpha_N PF04086.8 CBZ51330.1 - 8.7 5.6 12.5 16 4.7 8.7 1.4 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Radical_SAM PF04055.16 CBZ51332.1 - 2.4e-14 53.8 0.0 7.3e-14 52.2 0.0 1.8 1 0 0 1 1 1 1 Radical SAM superfamily Acetyltransf_1 PF00583.19 CBZ51332.1 - 3e-07 30.3 0.3 1.1e-06 28.6 0.1 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family CNRIP1 PF15043.1 CBZ51332.1 - 0.041 13.1 0.0 0.075 12.2 0.0 1.3 1 0 0 1 1 1 0 CB1 cannabinoid receptor-interacting protein 1 PDCD2_C PF04194.8 CBZ51333.1 - 8.1e-27 93.8 0.1 1.6e-26 92.8 0.1 1.5 1 0 0 1 1 1 1 Programmed cell death protein 2, C-terminal putative domain GFO_IDH_MocA PF01408.17 CBZ51334.1 - 0.00075 20.0 0.0 0.0018 18.7 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Ribosomal_S5 PF00333.15 CBZ51335.1 - 2.1e-28 97.8 0.4 4e-28 96.9 0.3 1.5 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.10 CBZ51335.1 - 9.8e-21 72.8 0.0 2.1e-20 71.7 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain FoP_duplication PF13865.1 CBZ51335.1 - 2.9 8.4 5.7 7.2 7.1 3.9 1.7 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 RhoGAP PF00620.22 CBZ51336.1 - 0.037 13.6 0.0 0.047 13.2 0.0 1.3 1 0 0 1 1 1 0 RhoGAP domain Met_synt_B12 PF02965.12 CBZ51336.1 - 0.091 11.9 0.1 0.33 10.1 0.0 1.8 2 0 0 2 2 2 0 Vitamin B12 dependent methionine synthase, activation domain DUF1769 PF08588.5 CBZ51337.1 - 0.00016 21.5 0.0 0.00039 20.2 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1769) Vps51 PF08700.6 CBZ51338.1 - 1.1e-18 66.8 0.0 2.7e-18 65.5 0.0 1.7 1 0 0 1 1 1 1 Vps51/Vps67 Sec5 PF15469.1 CBZ51338.1 - 7.2e-11 42.1 0.0 1.2e-10 41.3 0.0 1.4 1 0 0 1 1 1 1 Exocyst complex component Sec5 COG2 PF06148.6 CBZ51338.1 - 4.6e-06 26.5 1.6 4.6e-06 26.5 1.1 2.1 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 Dor1 PF04124.7 CBZ51338.1 - 0.00047 18.7 0.5 0.0011 17.5 0.4 1.6 1 0 0 1 1 1 1 Dor1-like family DUF1664 PF07889.7 CBZ51339.1 - 0.55 10.0 5.2 0.24 11.1 0.5 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) DUF342 PF03961.8 CBZ51339.1 - 3 6.1 17.1 0.54 8.6 2.7 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF342) Ank_2 PF12796.2 CBZ51340.1 - 8.4e-25 86.9 0.1 4.3e-19 68.6 0.2 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 CBZ51340.1 - 1.1e-22 78.5 0.1 7e-09 35.0 0.2 4.5 3 1 1 4 4 4 3 Ankyrin repeat Ank_3 PF13606.1 CBZ51340.1 - 1.2e-16 59.1 4.1 3.7e-07 29.7 0.2 4.8 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.1 CBZ51340.1 - 2.5e-16 59.3 0.3 2.5e-09 37.0 0.2 3.7 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 CBZ51340.1 - 9.7e-15 54.6 0.2 4.5e-11 42.9 0.2 2.7 2 0 0 2 2 2 2 Ankyrin repeats (many copies) ABC_tran PF00005.22 CBZ51341.1 - 3.9e-32 111.4 0.0 4e-18 66.0 0.0 3.0 2 1 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 CBZ51341.1 - 2.8e-22 79.4 20.9 1.8e-17 63.6 0.6 3.4 3 0 0 3 3 3 2 ABC transporter transmembrane region AAA_16 PF13191.1 CBZ51341.1 - 2.1e-09 37.6 0.2 0.0013 18.8 0.0 2.9 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 CBZ51341.1 - 1.4e-07 30.9 0.0 0.0072 15.8 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.18 CBZ51341.1 - 1.1e-05 25.3 0.1 0.055 13.4 0.1 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_17 PF13207.1 CBZ51341.1 - 6.1e-05 23.8 0.1 0.18 12.6 0.1 2.8 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.1 CBZ51341.1 - 7.1e-05 23.2 0.0 0.068 13.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.1 CBZ51341.1 - 8.3e-05 22.6 0.1 0.014 15.4 0.0 3.2 4 0 0 4 4 4 1 AAA domain AAA_22 PF13401.1 CBZ51341.1 - 0.00023 21.3 0.2 0.3 11.2 0.0 2.7 2 0 0 2 2 2 1 AAA domain ArgK PF03308.11 CBZ51341.1 - 0.00035 19.4 0.1 0.044 12.5 0.0 2.3 2 0 0 2 2 2 1 ArgK protein AAA_25 PF13481.1 CBZ51341.1 - 0.00047 19.6 0.0 0.48 9.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 CBZ51341.1 - 0.00049 20.0 0.2 0.16 11.8 0.0 3.0 2 0 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.13 CBZ51341.1 - 0.00079 18.9 0.0 0.012 15.1 0.0 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family DUF258 PF03193.11 CBZ51341.1 - 0.0008 18.6 0.1 1.2 8.3 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_18 PF13238.1 CBZ51341.1 - 0.00089 19.5 4.4 0.42 10.9 0.1 3.4 3 1 0 4 4 3 2 AAA domain Zeta_toxin PF06414.7 CBZ51341.1 - 0.0013 17.9 0.4 0.81 8.7 0.0 3.1 4 0 0 4 4 3 1 Zeta toxin DUF87 PF01935.12 CBZ51341.1 - 0.0023 17.7 0.1 0.0056 16.5 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function DUF87 Mg_chelatase PF01078.16 CBZ51341.1 - 0.0028 16.8 0.1 0.91 8.6 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA PF00004.24 CBZ51341.1 - 0.0032 17.6 1.0 0.0093 16.1 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.8 CBZ51341.1 - 0.0057 15.6 0.3 0.56 9.0 0.0 2.6 3 0 0 3 3 2 1 Protein of unknown function (DUF815) Rad17 PF03215.10 CBZ51341.1 - 0.0082 14.8 0.0 0.017 13.8 0.0 1.4 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA_5 PF07728.9 CBZ51341.1 - 0.0091 15.7 0.7 1.3 8.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) SMC_N PF02463.14 CBZ51341.1 - 0.011 15.0 0.0 2.4 7.3 0.0 2.3 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain Miro PF08477.8 CBZ51341.1 - 0.011 16.2 0.2 0.56 10.7 0.1 2.6 2 0 0 2 2 2 0 Miro-like protein T2SE PF00437.15 CBZ51341.1 - 0.013 14.3 0.0 0.44 9.4 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_10 PF12846.2 CBZ51341.1 - 0.017 14.5 0.1 0.36 10.2 0.1 2.3 2 0 0 2 2 2 0 AAA-like domain NACHT PF05729.7 CBZ51341.1 - 0.022 14.4 0.5 2.3 7.8 0.2 2.5 2 0 0 2 2 2 0 NACHT domain NTPase_1 PF03266.10 CBZ51341.1 - 0.028 14.1 0.1 5.2 6.7 0.0 2.6 2 0 0 2 2 2 0 NTPase RNA_helicase PF00910.17 CBZ51341.1 - 0.035 14.2 0.2 2.4 8.3 0.0 2.5 2 0 0 2 2 2 0 RNA helicase AAA_28 PF13521.1 CBZ51341.1 - 0.036 14.0 0.4 3.6 7.5 0.0 2.7 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.17 CBZ51341.1 - 0.039 12.7 0.0 0.43 9.3 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain PduV-EutP PF10662.4 CBZ51341.1 - 0.044 13.2 0.1 0.31 10.5 0.0 2.1 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Arch_ATPase PF01637.13 CBZ51341.1 - 0.085 12.5 0.0 5.6 6.5 0.0 2.3 2 0 0 2 2 2 0 Archaeal ATPase TrwB_AAD_bind PF10412.4 CBZ51341.1 - 0.092 11.3 0.1 3.4 6.1 0.1 2.8 3 0 0 3 3 3 0 Type IV secretion-system coupling protein DNA-binding domain AAA_19 PF13245.1 CBZ51341.1 - 0.093 12.5 5.8 0.43 10.3 0.0 3.9 4 0 0 4 4 3 0 Part of AAA domain cobW PF02492.14 CBZ51341.1 - 0.098 12.0 0.3 12 5.3 0.1 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Dynamin_N PF00350.18 CBZ51341.1 - 0.11 12.2 0.2 2.9 7.7 0.0 2.4 2 0 0 2 2 2 0 Dynamin family Viral_helicase1 PF01443.13 CBZ51341.1 - 0.12 11.9 0.3 3.4 7.1 0.0 2.3 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase MobB PF03205.9 CBZ51341.1 - 0.17 11.5 0.1 1 9.0 0.0 2.1 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_14 PF13173.1 CBZ51341.1 - 0.34 10.8 0.1 7.7 6.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain Nol1_Nop2_Fmu PF01189.12 CBZ51343.1 - 1e-15 57.8 0.1 2.1e-07 30.6 0.0 3.2 3 0 0 3 3 3 3 NOL1/NOP2/sun family UbiA PF01040.13 CBZ51344.1 - 1.9e-21 76.4 11.7 1.9e-21 76.4 8.1 1.5 2 0 0 2 2 2 1 UbiA prenyltransferase family Prok-RING_1 PF14446.1 CBZ51346.1 - 7.4e-06 25.6 4.8 7.4e-06 25.6 3.3 3.4 3 1 0 3 3 3 1 Prokaryotic RING finger family 1 zf-rbx1 PF12678.2 CBZ51346.1 - 1.7e-05 24.7 15.7 7.8e-05 22.7 1.8 3.5 3 0 0 3 3 3 1 RING-H2 zinc finger zf-RING_2 PF13639.1 CBZ51346.1 - 2.6e-05 23.9 29.4 9.4e-05 22.1 3.9 3.7 3 0 0 3 3 3 2 Ring finger domain zf-C3HC4 PF00097.20 CBZ51346.1 - 0.0028 17.2 3.5 0.0028 17.2 2.4 3.8 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) OrfB_Zn_ribbon PF07282.6 CBZ51346.1 - 0.0062 16.1 0.9 0.0062 16.1 0.6 2.2 2 0 0 2 2 2 1 Putative transposase DNA-binding domain zf-Apc11 PF12861.2 CBZ51346.1 - 0.0063 16.3 14.1 0.0086 15.8 0.8 2.9 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 11 RING-H2 finger PHF5 PF03660.9 CBZ51346.1 - 0.046 13.7 3.2 0.13 12.3 2.2 1.7 1 0 0 1 1 1 0 PHF5-like protein zf-ribbon_3 PF13248.1 CBZ51346.1 - 2.2 7.6 8.0 0.69 9.1 1.8 2.7 2 0 0 2 2 2 0 zinc-ribbon domain ER_lumen_recept PF00810.13 CBZ51348.1 - 1.1e-11 45.3 17.2 3.2e-10 40.6 8.8 2.4 2 1 0 2 2 2 1 ER lumen protein retaining receptor PQ-loop PF04193.9 CBZ51348.1 - 0.02 14.4 0.7 0.02 14.4 0.5 2.4 3 1 0 3 3 3 0 PQ loop repeat V_ATPase_I PF01496.14 CBZ51348.1 - 0.82 7.4 4.9 0.98 7.1 3.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Atg14 PF10186.4 CBZ51349.1 - 0.044 12.7 0.3 1.6 7.6 0.0 2.9 3 0 0 3 3 3 0 UV radiation resistance protein and autophagy-related subunit 14 Prominin PF05478.6 CBZ51349.1 - 4.9 4.5 0.1 7 4.0 0.0 1.1 1 0 0 1 1 1 0 Prominin Hus1 PF04005.7 CBZ51350.1 - 1.6e-21 76.5 0.0 7e-21 74.4 0.0 1.8 1 1 0 1 1 1 1 Hus1-like protein FAD_binding_7 PF03441.9 CBZ51351.1 - 4.6e-35 121.1 0.1 3.6e-34 118.2 0.1 2.1 1 1 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.13 CBZ51351.1 - 7.3e-14 51.8 0.0 1.4e-13 50.8 0.0 1.5 1 0 0 1 1 1 1 DNA photolyase Methyltransf_3 PF01596.12 CBZ51351.1 - 0.029 13.4 0.1 0.049 12.6 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase Myosin_head PF00063.16 CBZ51352.1 - 4.6e-121 405.0 0.0 9.6e-78 261.8 0.0 4.2 3 2 0 3 3 3 3 Myosin head (motor domain) IQ PF00612.22 CBZ51352.1 - 0.0012 18.2 26.8 0.0014 18.0 0.0 5.1 5 0 0 5 5 5 3 IQ calmodulin-binding motif AAA_22 PF13401.1 CBZ51352.1 - 0.03 14.4 0.0 0.1 12.7 0.0 1.9 1 0 0 1 1 1 0 AAA domain FH2 PF02181.18 CBZ51353.1 - 1.3e-68 231.5 0.4 2.1e-68 230.9 0.3 1.2 1 0 0 1 1 1 1 Formin Homology 2 Domain TPR_10 PF13374.1 CBZ51353.1 - 1.8e-21 75.3 0.0 1.6e-12 46.9 0.0 4.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.1 CBZ51353.1 - 1.4e-16 60.2 2.0 8.5e-09 35.2 0.0 3.5 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.1 CBZ51353.1 - 1.4e-05 24.5 0.9 0.0003 20.3 0.0 3.1 3 0 0 3 3 3 1 TPR repeat TPR_2 PF07719.12 CBZ51353.1 - 6.3e-05 22.5 1.4 1.7 8.7 0.3 4.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 CBZ51353.1 - 0.00056 19.4 4.1 2 8.1 0.2 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.1 CBZ51353.1 - 0.013 15.2 0.1 3.1 7.8 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat CPW_WPC PF09717.5 CBZ51354.1 - 6.2e-13 49.1 5.6 1.1e-12 48.4 3.9 1.5 1 0 0 1 1 1 1 Plasmodium falciparum domain of unknown function (CPW_WPC) Peptidase_C54 PF03416.14 CBZ51355.1 - 6.3e-37 127.2 0.0 3.5e-16 59.1 0.0 3.8 4 0 0 4 4 4 3 Peptidase family C54 Pyr_redox_2 PF07992.9 CBZ51356.1 - 1.6e-37 129.3 7.8 1.7e-35 122.7 5.4 4.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.17 CBZ51356.1 - 3.1e-34 117.3 0.1 8e-34 115.9 0.0 1.8 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.22 CBZ51356.1 - 4.5e-24 84.6 8.8 8.1e-21 74.2 0.2 3.9 4 1 1 5 5 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 CBZ51356.1 - 1.1e-10 41.1 6.1 3.7e-10 39.4 2.9 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 CBZ51356.1 - 3.5e-08 33.7 0.4 6.7e-06 26.2 0.1 2.4 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 CBZ51356.1 - 4.4e-07 29.0 3.9 4.4e-07 29.0 2.7 3.2 3 1 1 4 4 4 1 FAD binding domain GIDA PF01134.17 CBZ51356.1 - 1.1e-06 27.7 7.2 3.8e-06 26.0 3.5 2.6 2 1 0 2 2 2 1 Glucose inhibited division protein A DAO PF01266.19 CBZ51356.1 - 5.4e-06 25.5 12.8 0.012 14.5 1.2 4.2 4 0 0 4 4 4 2 FAD dependent oxidoreductase Thi4 PF01946.12 CBZ51356.1 - 1.3e-05 24.4 0.7 3.1e-05 23.1 0.5 1.6 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.9 CBZ51356.1 - 1.6e-05 23.5 10.3 0.00057 18.4 1.5 3.7 2 2 2 4 4 4 2 HI0933-like protein NAD_binding_8 PF13450.1 CBZ51356.1 - 5.2e-05 23.1 7.5 0.002 18.1 1.6 2.6 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 CBZ51356.1 - 0.0029 16.7 10.5 0.0098 14.9 0.8 3.1 2 1 1 3 3 3 2 FAD binding domain AlaDh_PNT_C PF01262.16 CBZ51356.1 - 0.016 14.8 4.6 0.045 13.3 0.1 2.6 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain K_oxygenase PF13434.1 CBZ51356.1 - 0.028 13.3 1.0 0.61 8.9 0.0 2.6 3 0 0 3 3 3 0 L-lysine 6-monooxygenase (NADPH-requiring) 3HCDH_N PF02737.13 CBZ51356.1 - 0.071 12.7 0.1 0.071 12.7 0.1 2.8 3 0 0 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_7 PF13241.1 CBZ51356.1 - 1.2 9.4 4.1 8.2 6.7 0.0 3.1 2 1 0 2 2 2 0 Putative NAD(P)-binding Lycopene_cycl PF05834.7 CBZ51356.1 - 2.6 6.8 4.8 0.67 8.8 0.4 2.0 3 0 0 3 3 3 0 Lycopene cyclase protein Peptidase_C14 PF00656.17 CBZ51357.1 - 4.4e-55 187.0 0.0 2.3e-54 184.7 0.0 2.0 2 0 0 2 2 2 1 Caspase domain CUE PF02845.11 CBZ51357.1 - 0.0029 17.0 0.0 0.0053 16.2 0.0 1.4 1 0 0 1 1 1 1 CUE domain CC2D2AN-C2 PF15625.1 CBZ51357.1 - 0.06 12.8 0.0 0.12 11.7 0.0 1.5 1 0 0 1 1 1 0 CC2D2A N-terminal C2 domain C2 PF00168.25 CBZ51357.1 - 0.12 12.2 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 C2 domain Pro-rich PF15240.1 CBZ51357.1 - 5.3 7.1 36.0 10 6.1 25.0 1.4 1 0 0 1 1 1 0 Proline-rich UPF0020 PF01170.13 CBZ51358.1 - 1.6e-06 27.8 0.0 6.1e-06 25.9 0.0 1.9 2 0 0 2 2 2 1 Putative RNA methylase family UPF0020 Peptidase_M16 PF00675.15 CBZ51359.1 - 2.3e-24 85.8 0.2 5.4e-23 81.4 0.0 2.7 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 CBZ51359.1 - 4.2e-10 39.6 0.4 7e-06 25.8 0.0 3.7 4 0 0 4 4 4 2 Peptidase M16 inactive domain PapD-like PF14874.1 CBZ51361.1 - 2.4e-20 72.3 16.3 0.0048 16.8 0.0 15.6 18 0 0 18 18 18 2 Flagellar-associated PapD-like Motile_Sperm PF00635.21 CBZ51361.1 - 8.2e-18 64.0 3.2 0.004 16.7 0.0 14.0 16 0 0 16 16 16 1 MSP (Major sperm protein) domain CARDB PF07705.6 CBZ51361.1 - 0.0036 17.3 0.0 17 5.5 0.0 6.5 7 0 0 7 7 6 0 CARDB AAA_16 PF13191.1 CBZ51361.1 - 0.0039 17.2 0.2 0.018 15.0 0.1 2.1 1 1 0 1 1 1 1 AAA ATPase domain MYCBPAP PF14646.1 CBZ51361.1 - 0.0046 15.7 0.0 21 3.7 0.0 5.4 7 0 0 7 7 7 0 MYCBP-associated protein family AAA_17 PF13207.1 CBZ51361.1 - 0.053 14.3 0.0 0.23 12.2 0.0 2.1 2 0 0 2 2 1 0 AAA domain SKI PF01202.17 CBZ51361.1 - 0.093 12.5 0.1 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 Shikimate kinase AAA PF00004.24 CBZ51361.1 - 0.13 12.4 0.0 0.28 11.4 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.1 CBZ51361.1 - 0.21 11.1 0.0 0.36 10.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 CBZ51361.1 - 0.21 11.7 0.0 1.4 9.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.21 CBZ51361.1 - 0.78 9.1 0.0 1.5 8.2 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_18 PF13238.1 CBZ51361.1 - 1 9.6 0.0 2.1 8.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain EF-hand_7 PF13499.1 CBZ51362.1 - 2.5e-16 59.5 0.3 5.3e-11 42.5 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 CBZ51362.1 - 4.5e-12 45.3 1.1 2.5e-07 30.1 0.1 3.2 2 2 1 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.27 CBZ51362.1 - 2.9e-11 41.8 0.3 0.0043 16.2 0.0 3.5 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.1 CBZ51362.1 - 4.4e-11 41.6 0.9 2.4e-05 23.8 0.0 3.5 3 0 0 3 3 3 3 EF-hand domain EF-hand_5 PF13202.1 CBZ51362.1 - 7e-07 28.3 0.0 0.0023 17.2 0.0 3.0 3 0 0 3 3 3 2 EF hand EF-hand_9 PF14658.1 CBZ51362.1 - 0.056 13.3 0.0 3.5 7.6 0.0 2.6 2 1 0 2 2 2 0 EF-hand domain Kinesin PF00225.18 CBZ51363.1 - 1e-62 211.7 0.2 4.5e-41 140.6 0.0 3.8 3 1 1 4 4 4 2 Kinesin motor domain Allexi_40kDa PF05549.6 CBZ51363.1 - 0.0097 15.2 0.1 0.025 13.8 0.1 1.6 1 0 0 1 1 1 1 Allexivirus 40kDa protein FAM176 PF14851.1 CBZ51363.1 - 6.7 6.3 16.3 0.91 9.1 0.0 3.3 3 1 0 3 3 3 0 FAM176 family FH2 PF02181.18 CBZ51364.1 - 4.7e-43 147.4 0.4 2.3e-34 118.8 0.2 2.2 2 0 0 2 2 2 2 Formin Homology 2 Domain PTEN_C2 PF10409.4 CBZ51364.1 - 0.069 12.8 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 C2 domain of PTEN tumour-suppressor protein ABC1 PF03109.11 CBZ51364.1 - 1.5 8.7 0.1 4.3 7.3 0.0 1.7 1 0 0 1 1 1 0 ABC1 family Cytochrom_B561 PF03188.11 CBZ51364.1 - 8.6 6.1 0.1 15 5.3 0.1 1.2 1 0 0 1 1 1 0 Eukaryotic cytochrome b561 tRNA_Me_trans PF03054.11 CBZ51364.1 - 9 4.7 0.0 37 2.7 0.0 1.7 2 0 0 2 2 2 0 tRNA methyl transferase Pkinase PF00069.20 CBZ51365.1 - 2.7e-76 256.1 0.0 4.2e-76 255.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ51365.1 - 5.1e-37 127.3 0.0 7.4e-37 126.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_1 PF00036.27 CBZ51365.1 - 6.1e-29 97.0 7.5 1.7e-06 26.8 0.9 4.6 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 CBZ51365.1 - 2.7e-26 91.4 0.9 7.4e-12 45.2 0.0 3.0 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 CBZ51365.1 - 3e-22 76.4 2.9 2.7e-06 26.8 0.0 4.6 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.1 CBZ51365.1 - 3.6e-20 71.3 9.7 1.1e-05 24.8 1.2 4.9 2 1 2 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.1 CBZ51365.1 - 1.2e-19 68.6 5.8 2.3e-06 26.6 0.1 4.7 4 0 0 4 4 4 4 EF hand Kinase-like PF14531.1 CBZ51365.1 - 2e-06 27.0 0.0 5.1e-06 25.6 0.0 1.7 1 1 0 1 1 1 1 Kinase-like EF-hand_4 PF12763.2 CBZ51365.1 - 1.1e-05 25.0 1.7 0.048 13.3 0.1 3.1 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 CBZ51365.1 - 0.00011 22.1 0.0 0.37 10.8 0.0 2.5 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region Kdo PF06293.9 CBZ51365.1 - 0.005 15.9 0.0 0.0098 14.9 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CBZ51365.1 - 0.0075 16.0 0.0 0.054 13.2 0.0 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Prenyltransf PF01255.14 CBZ51365.1 - 0.01 14.9 0.1 0.021 13.9 0.0 1.4 1 0 0 1 1 1 0 Putative undecaprenyl diphosphate synthase EF-hand_9 PF14658.1 CBZ51365.1 - 0.014 15.3 0.1 0.29 11.0 0.0 2.5 2 0 0 2 2 2 0 EF-hand domain DUF2267 PF10025.4 CBZ51365.1 - 0.09 12.8 0.0 0.47 10.5 0.0 2.2 2 1 0 2 2 1 0 Uncharacterized conserved protein (DUF2267) Sigma70_r3 PF04539.11 CBZ51366.1 - 3.7e-10 39.5 0.2 2e-09 37.2 0.1 2.4 1 0 0 1 1 1 1 Sigma-70 region 3 2-oxoacid_dh PF00198.18 CBZ51367.1 - 4.1e-60 202.9 0.5 6.9e-60 202.1 0.1 1.6 2 0 0 2 2 2 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 CBZ51367.1 - 1.6e-52 175.0 10.3 3.5e-17 61.7 0.1 3.4 3 0 0 3 3 3 3 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.1 CBZ51367.1 - 1.8e-13 49.9 12.2 0.0011 18.5 0.0 5.9 4 3 3 7 7 7 3 Biotin-lipoyl like HlyD_2 PF12700.2 CBZ51367.1 - 4e-06 26.2 2.0 13 4.8 0.0 5.6 3 3 3 6 6 6 0 HlyD family secretion protein HlyD_3 PF13437.1 CBZ51367.1 - 5.8e-06 26.5 8.6 5.2 7.4 0.0 5.8 3 3 3 6 6 6 3 HlyD family secretion protein PYNP_C PF07831.8 CBZ51367.1 - 1.2e-05 24.6 0.9 4.6 6.7 0.0 4.5 4 0 0 4 4 4 2 Pyrimidine nucleoside phosphorylase C-terminal domain E3_binding PF02817.12 CBZ51367.1 - 1.5e-05 24.5 0.1 3.9e-05 23.1 0.0 1.8 1 0 0 1 1 1 1 e3 binding domain GCV_H PF01597.14 CBZ51367.1 - 0.00012 21.7 1.4 0.52 9.9 0.0 3.6 3 0 0 3 3 3 2 Glycine cleavage H-protein QRPTase_N PF02749.11 CBZ51367.1 - 0.0027 17.5 0.2 5.2 6.9 0.0 3.6 3 0 0 3 3 3 1 Quinolinate phosphoribosyl transferase, N-terminal domain DUF2118 PF09891.4 CBZ51367.1 - 0.003 17.2 1.0 0.91 9.2 0.0 3.3 3 1 0 3 3 3 1 Uncharacterized protein conserved in archaea (DUF2118) Imm5 PF14423.1 CBZ51367.1 - 0.23 11.0 0.4 2.9 7.4 0.0 2.2 2 0 0 2 2 2 0 Immunity protein Imm5 DUF515 PF04415.7 CBZ51367.1 - 0.87 7.7 4.0 1.8 6.6 2.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF515) Abi PF02517.11 CBZ51368.1 - 2.9e-05 24.1 0.6 2.9e-05 24.1 0.4 3.0 2 1 0 2 2 2 1 CAAX protease self-immunity zf-H2C2_2 PF13465.1 CBZ51370.1 - 3.5e-20 71.2 12.5 9.5e-07 28.8 0.0 4.5 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2 PF00096.21 CBZ51370.1 - 6.4e-16 57.6 27.0 0.00013 22.0 3.9 5.0 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CBZ51370.1 - 5.2e-15 54.5 27.8 0.00085 19.4 0.5 4.8 4 0 0 4 4 4 4 C2H2-type zinc finger zf-Di19 PF05605.7 CBZ51370.1 - 2.5e-06 27.5 14.4 0.00094 19.2 2.7 2.5 2 0 0 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_5 PF13909.1 CBZ51370.1 - 0.012 15.8 26.1 0.02 15.1 1.0 4.7 4 0 0 4 4 4 0 C2H2-type zinc-finger domain zf-Apc11 PF12861.2 CBZ51370.1 - 0.19 11.6 0.9 4.7 7.1 0.2 2.8 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-BED PF02892.10 CBZ51370.1 - 0.27 11.0 14.3 0.21 11.3 0.8 3.6 1 1 2 3 3 3 0 BED zinc finger zf-C2H2_6 PF13912.1 CBZ51370.1 - 0.48 10.4 14.4 4.5 7.3 0.1 3.9 4 0 0 4 4 3 0 C2H2-type zinc finger Elf1 PF05129.8 CBZ51370.1 - 1.1 8.9 5.5 3.8 7.2 0.0 2.9 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like zf-met PF12874.2 CBZ51370.1 - 1.6 9.0 20.1 2 8.7 0.1 4.4 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 CBZ51370.1 - 2.7 8.2 17.3 0.69 10.1 1.5 4.0 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding Zn_Tnp_IS1595 PF12760.2 CBZ51370.1 - 3.8 7.3 10.6 0.46 10.3 1.3 3.0 2 1 1 3 3 3 0 Transposase zinc-ribbon domain DUF164 PF02591.10 CBZ51370.1 - 4.2 7.2 5.2 21 5.0 0.1 3.2 3 0 0 3 3 3 0 Putative zinc ribbon domain RRM_1 PF00076.17 CBZ51372.1 - 7.9e-10 38.2 0.0 3.4e-05 23.3 0.0 3.4 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBZ51372.1 - 5.7e-08 32.4 0.0 0.00019 21.1 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBZ51372.1 - 1.3e-05 25.0 0.1 0.3 11.0 0.0 3.1 3 1 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) SPOC PF07744.8 CBZ51372.1 - 0.0039 17.6 0.0 0.009 16.4 0.0 1.6 1 0 0 1 1 1 1 SPOC domain DUF3273 PF11677.3 CBZ51373.1 - 7.1e-83 277.9 10.7 8.8e-83 277.6 7.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3273) DUF4520 PF15016.1 CBZ51374.1 - 0.059 12.9 0.0 0.21 11.1 0.0 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4520) Extensin-like_C PF06904.7 CBZ51374.1 - 0.063 13.0 1.0 0.094 12.4 0.2 1.6 2 0 0 2 2 2 0 Extensin-like protein C-terminus Fringe PF02434.11 CBZ51374.1 - 0.096 11.8 0.0 0.14 11.3 0.0 1.2 1 0 0 1 1 1 0 Fringe-like UQ_con PF00179.21 CBZ51376.1 - 5.4e-46 155.4 0.0 6.3e-46 155.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 CBZ51376.1 - 0.0015 18.2 0.0 0.0019 17.9 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.8 CBZ51376.1 - 0.0027 17.3 0.0 0.0051 16.5 0.0 1.5 1 1 0 1 1 1 1 UEV domain RWD PF05773.17 CBZ51376.1 - 0.022 14.6 1.0 0.055 13.3 0.7 1.8 1 1 0 1 1 1 0 RWD domain RRM_1 PF00076.17 CBZ51377.1 - 1.6e-15 56.4 0.0 1.9e-06 27.4 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBZ51377.1 - 7.4e-13 48.2 0.0 1.6e-05 24.7 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBZ51377.1 - 1.1e-08 34.7 0.0 0.0016 18.2 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 CBZ51377.1 - 0.068 12.9 0.0 1.3 8.7 0.0 2.4 2 0 0 2 2 2 0 Limkain b1 zf-C3HC4_3 PF13920.1 CBZ51378.1 - 2.2e-11 43.2 6.5 3.8e-11 42.4 4.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CBZ51378.1 - 2.6e-06 27.3 11.6 4.9e-06 26.4 8.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CBZ51378.1 - 0.0016 18.0 8.9 0.0027 17.3 6.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CBZ51378.1 - 0.0055 16.5 10.5 0.01 15.6 7.3 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 CBZ51378.1 - 0.097 12.4 11.2 0.18 11.5 7.8 1.4 1 0 0 1 1 1 0 zinc-RING finger domain Pkinase PF00069.20 CBZ51379.1 - 1.3e-22 80.1 0.0 2.1e-18 66.4 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ51379.1 - 1.7e-07 30.5 0.0 1.5e-06 27.4 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBZ51379.1 - 0.011 14.7 0.0 0.018 14.0 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Glyco_transf_5 PF08323.6 CBZ51379.1 - 0.047 13.1 0.0 0.077 12.4 0.0 1.2 1 0 0 1 1 1 0 Starch synthase catalytic domain AGT PF11440.3 CBZ51379.1 - 0.065 12.1 0.0 0.097 11.5 0.0 1.1 1 0 0 1 1 1 0 DNA alpha-glucosyltransferase Mob1_phocein PF03637.12 CBZ51380.1 - 2.4e-17 63.1 0.1 3.9e-17 62.4 0.1 1.3 1 0 0 1 1 1 1 Mob1/phocein family DUF3883 PF13020.1 CBZ51381.1 - 3.9e-20 71.3 0.0 7.4e-20 70.4 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3883) eRF1_2 PF03464.10 CBZ51382.1 - 4.4e-45 153.2 0.1 7.6e-45 152.4 0.1 1.4 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.10 CBZ51382.1 - 1.4e-36 125.2 0.1 3.1e-36 124.0 0.1 1.6 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.10 CBZ51382.1 - 1.5e-26 92.5 0.1 3.5e-26 91.3 0.1 1.6 1 0 0 1 1 1 1 eRF1 domain 1 Ribosomal_L7Ae PF01248.21 CBZ51382.1 - 0.027 13.9 0.0 0.059 12.8 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family N-Term_TEN PF11474.3 CBZ51382.1 - 0.043 13.1 0.1 0.13 11.5 0.1 1.8 2 0 0 2 2 2 0 Telomerase reverse transcriptase TEN domain Asp_protease PF09668.5 CBZ51384.1 - 1.6e-53 179.4 0.0 2.6e-53 178.8 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease Asp_protease_2 PF13650.1 CBZ51384.1 - 3.2e-11 43.5 0.0 1.7e-10 41.2 0.0 2.2 2 0 0 2 2 2 1 Aspartyl protease ubiquitin PF00240.18 CBZ51384.1 - 1.6e-09 37.0 0.0 4e-09 35.7 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.26 CBZ51384.1 - 1e-07 31.5 0.2 3e-07 30.0 0.1 1.9 1 0 0 1 1 1 1 UBA/TS-N domain RVP PF00077.15 CBZ51384.1 - 1.1e-06 28.4 0.0 2.7e-06 27.2 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease RVP_2 PF08284.6 CBZ51384.1 - 2.1e-06 27.7 0.1 7.4e-06 25.9 0.0 1.9 2 0 0 2 2 2 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 CBZ51384.1 - 1.3e-05 24.8 0.0 8.2e-05 22.3 0.0 2.4 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Rad60-SLD PF11976.3 CBZ51384.1 - 0.00019 21.0 0.0 0.00086 18.9 0.0 2.1 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like Rootletin PF15035.1 CBZ51384.1 - 0.015 15.2 2.7 0.025 14.5 1.9 1.3 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion Pil1 PF13805.1 CBZ51384.1 - 0.058 12.5 1.6 0.13 11.3 1.1 1.5 1 0 0 1 1 1 0 Eisosome component PIL1 DUF4239 PF14023.1 CBZ51384.1 - 0.15 11.3 0.1 0.28 10.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4239) DUF4381 PF14316.1 CBZ51385.1 - 0.0089 16.1 4.2 0.69 10.0 0.6 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF4381) IspD PF01128.14 CBZ51387.1 - 1.1e-12 48.0 1.5 5.7e-08 32.5 0.4 3.5 4 0 0 4 4 4 3 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase Med7 PF05983.6 CBZ51389.1 - 1.6e-13 50.7 0.0 2.4e-13 50.1 0.0 1.4 1 1 0 1 1 1 1 MED7 protein DUF2077 PF09850.4 CBZ51389.1 - 0.11 11.8 0.9 0.21 10.9 0.6 1.6 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2077) RNA_pol_Rpb1_5 PF04998.12 CBZ51390.1 - 3.7e-94 315.0 0.0 5.6e-94 314.4 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_1 PF04997.7 CBZ51390.1 - 6.3e-76 255.8 0.0 8.8e-76 255.3 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.15 CBZ51390.1 - 2e-66 223.0 0.0 7.1e-66 221.2 0.0 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 CBZ51390.1 - 9.1e-35 119.7 0.0 1.8e-34 118.7 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.12 CBZ51390.1 - 6e-30 103.1 0.0 1.4e-29 101.9 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 Macoilin PF09726.4 CBZ51390.1 - 9.5 4.3 19.0 14 3.8 13.2 1.1 1 0 0 1 1 1 0 Transmembrane protein TRAP_alpha PF03896.11 CBZ51391.1 - 2.9 6.8 5.4 8.4 5.2 3.7 1.7 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit SMC_N PF02463.14 CBZ51392.1 - 1.3e-40 139.0 0.0 3e-40 137.7 0.0 1.6 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 CBZ51392.1 - 6.8e-13 49.4 14.1 6.8e-13 49.4 9.8 7.2 4 2 0 4 4 4 1 AAA domain SMC_hinge PF06470.8 CBZ51392.1 - 6.5e-11 42.2 0.2 2.9e-09 36.9 0.1 3.4 3 1 0 3 3 3 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 CBZ51392.1 - 1.3e-09 38.4 0.0 2.9e-05 24.1 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.1 CBZ51392.1 - 5.5e-07 28.9 0.0 0.00031 19.9 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain SbcCD_C PF13558.1 CBZ51392.1 - 2.7e-05 23.9 1.5 0.00011 21.9 0.1 2.8 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.1 CBZ51392.1 - 0.0059 16.1 0.0 0.013 15.0 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.22 CBZ51392.1 - 1.3 9.3 0.0 1.3 9.3 0.0 5.7 6 2 0 6 6 6 0 ABC transporter Myb_DNA-binding PF00249.26 CBZ51393.1 - 2.5e-13 49.8 0.5 4.8e-13 48.9 0.4 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 CBZ51393.1 - 2e-07 31.0 0.0 4.5e-07 29.8 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Abhydrolase_5 PF12695.2 CBZ51394.1 - 2.8e-09 36.8 0.0 7.3e-09 35.5 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 CBZ51394.1 - 2.4e-05 24.1 0.4 0.2 11.5 0.0 2.5 2 0 0 2 2 2 2 Putative lysophospholipase UPF0227 PF05728.7 CBZ51394.1 - 0.017 14.8 0.0 0.037 13.7 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Dynein_heavy PF03028.10 CBZ51395.1 - 8.7e-193 642.1 0.0 8.7e-193 642.1 0.0 2.2 2 0 0 2 2 2 1 Dynein heavy chain and region D6 of dynein motor DHC_N1 PF08385.7 CBZ51395.1 - 2.9e-124 415.5 12.0 2.9e-124 415.5 8.3 3.7 4 0 0 4 4 3 1 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.8 CBZ51395.1 - 1.1e-102 343.5 1.3 2.1e-63 214.2 0.0 4.6 6 0 0 6 6 6 2 Dynein heavy chain, N-terminal region 2 AAA_6 PF12774.2 CBZ51395.1 - 4.1e-80 268.6 0.1 1.4e-78 263.5 0.0 2.5 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region D1 AAA_8 PF12780.2 CBZ51395.1 - 6.1e-71 238.5 0.0 4e-70 235.8 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 AAA_9 PF12781.2 CBZ51395.1 - 1e-52 178.2 0.9 2.1e-52 177.2 0.7 1.6 1 0 0 1 1 1 1 ATP-binding dynein motor region D5 AAA_7 PF12775.2 CBZ51395.1 - 2.3e-35 122.0 0.0 5.6e-35 120.7 0.0 1.7 1 0 0 1 1 1 1 P-loop containing dynein motor region D3 MT PF12777.2 CBZ51395.1 - 4.1e-34 117.8 17.5 4.1e-34 117.8 12.1 2.8 2 1 0 2 2 2 1 Microtubule-binding stalk of dynein motor AAA_5 PF07728.9 CBZ51395.1 - 2.5e-18 66.1 0.0 9.6e-08 31.8 0.0 5.2 4 2 0 4 4 4 4 AAA domain (dynein-related subfamily) AAA PF00004.24 CBZ51395.1 - 3.9e-08 33.5 0.6 0.57 10.3 0.0 6.2 6 0 0 6 6 6 2 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 CBZ51395.1 - 0.00081 20.1 0.0 1.2 9.9 0.0 4.9 3 0 0 3 3 3 1 AAA domain AAA_33 PF13671.1 CBZ51395.1 - 0.0026 17.6 0.2 4 7.3 0.0 4.6 4 0 0 4 4 3 1 AAA domain Acyl-CoA_dh_2 PF08028.6 CBZ51395.1 - 0.03 14.5 3.3 0.12 12.6 2.3 2.0 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, C-terminal domain Bac_luciferase PF00296.15 CBZ51395.1 - 0.21 10.6 0.0 2.2 7.3 0.0 2.6 2 0 0 2 2 2 0 Luciferase-like monooxygenase AAA_19 PF13245.1 CBZ51395.1 - 3.9 7.2 9.6 26 4.6 0.5 4.2 4 0 0 4 4 4 0 Part of AAA domain IncA PF04156.9 CBZ51396.1 - 0.011 15.3 0.8 0.019 14.5 0.6 1.3 1 0 0 1 1 1 0 IncA protein Med15_fungi PF05397.7 CBZ51396.1 - 0.099 12.6 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 Mediator complex subunit 15 zf-U1 PF06220.7 CBZ51397.1 - 1.8e-18 65.7 2.3 2.9e-18 65.1 1.6 1.3 1 0 0 1 1 1 1 U1 zinc finger zf-C2H2_jaz PF12171.3 CBZ51397.1 - 0.00066 19.7 0.7 0.0012 18.9 0.5 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding COX6B PF02297.12 CBZ51398.1 - 0.0007 19.5 4.8 0.001 19.0 3.3 1.2 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb Sec34 PF04136.10 CBZ51400.1 - 3.5e-13 49.5 0.0 2e-08 34.0 0.0 2.4 2 0 0 2 2 2 2 Sec34-like family Sigma70_ner PF04546.8 CBZ51400.1 - 8.5e-06 25.5 10.5 0.0018 17.9 0.0 3.6 3 0 0 3 3 3 2 Sigma-70, non-essential region Reo_sigmaC PF04582.7 CBZ51401.1 - 0.0028 16.8 3.1 0.0028 16.8 2.1 1.9 2 0 0 2 2 2 1 Reovirus sigma C capsid protein Baculo_PEP_C PF04513.7 CBZ51401.1 - 8.4 6.2 22.7 2.7 7.8 1.0 3.5 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus PP1_bind PF15276.1 CBZ51402.1 - 0.034 14.1 0.1 0.11 12.5 0.1 1.8 1 0 0 1 1 1 0 Protein phosphatase 1 binding adh_short_C2 PF13561.1 CBZ51403.1 - 3.8e-25 89.0 0.1 4.2e-25 88.9 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 CBZ51403.1 - 2.8e-21 76.1 2.4 2.8e-21 76.1 1.6 1.5 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 CBZ51403.1 - 5.3e-09 36.0 1.3 8.2e-09 35.3 0.7 1.3 1 1 0 1 1 1 1 KR domain AroM PF07302.6 CBZ51403.1 - 0.022 14.1 0.0 0.029 13.6 0.0 1.2 1 0 0 1 1 1 0 AroM protein NAD_binding_10 PF13460.1 CBZ51403.1 - 0.054 13.5 0.0 0.3 11.0 0.0 2.2 2 1 0 3 3 3 0 NADH(P)-binding NAD_binding_7 PF13241.1 CBZ51403.1 - 0.089 13.0 0.0 0.15 12.3 0.0 1.6 1 1 0 1 1 1 0 Putative NAD(P)-binding Bromodomain PF00439.20 CBZ51404.1 - 6.5e-19 67.6 0.5 1.4e-18 66.5 0.3 1.5 1 0 0 1 1 1 1 Bromodomain ICMT PF04140.9 CBZ51405.1 - 1.1e-21 76.7 0.8 2.6e-21 75.6 0.5 1.6 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 CBZ51405.1 - 4.2e-12 46.1 2.6 4.2e-12 46.1 1.8 1.7 2 0 0 2 2 2 1 Phospholipid methyltransferase NnrU PF07298.6 CBZ51405.1 - 1.6e-05 24.4 0.6 3.9e-05 23.1 0.4 1.6 1 0 0 1 1 1 1 NnrU protein Pkinase PF00069.20 CBZ51406.1 - 2.8e-64 216.7 0.0 2.8e-35 121.7 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ51406.1 - 1.1e-29 103.2 0.0 5.9e-19 68.1 0.1 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.9 CBZ51406.1 - 0.072 12.1 0.1 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.6 CBZ51406.1 - 0.27 9.9 0.2 0.39 9.4 0.1 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Kinase-like PF14531.1 CBZ51406.1 - 0.57 9.0 0.2 19 4.0 0.0 2.1 2 0 0 2 2 2 0 Kinase-like BSD PF03909.12 CBZ51407.1 - 5.8e-07 29.1 0.2 1e-06 28.3 0.1 1.4 1 0 0 1 1 1 1 BSD domain DUF1632 PF07857.7 CBZ51408.1 - 0.0038 16.5 2.5 0.0084 15.3 1.8 1.5 1 0 0 1 1 1 1 CEO family (DUF1632) TruB_N PF01509.13 CBZ51410.1 - 4.9e-28 98.1 2.0 7e-19 68.4 0.0 3.2 2 1 1 3 3 3 3 TruB family pseudouridylate synthase (N terminal domain) Choline_kinase PF01633.15 CBZ51412.1 - 2e-37 128.8 0.0 6.1e-37 127.2 0.0 1.8 1 1 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.18 CBZ51412.1 - 5e-16 59.1 0.4 1.3e-14 54.5 0.0 2.5 1 1 1 2 2 2 1 Phosphotransferase enzyme family EcKinase PF02958.15 CBZ51412.1 - 0.00052 19.2 0.0 0.0014 17.8 0.0 1.6 1 0 0 1 1 1 1 Ecdysteroid kinase Fructosamin_kin PF03881.9 CBZ51412.1 - 0.045 12.7 0.0 0.15 10.9 0.0 1.7 2 0 0 2 2 2 0 Fructosamine kinase DUF1679 PF07914.6 CBZ51412.1 - 0.24 10.0 0.0 0.35 9.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) GHMP_kinases_N PF00288.21 CBZ51413.1 - 0.044 13.8 0.8 0.044 13.8 0.5 2.8 2 0 0 2 2 2 0 GHMP kinases N terminal domain Nucleoporin_FG PF13634.1 CBZ51414.1 - 2.8e-29 101.6 201.4 4.7e-09 36.4 28.9 6.4 2 2 3 5 5 5 5 Nucleoporin FG repeat region DUF1664 PF07889.7 CBZ51414.1 - 1.4 8.7 4.6 5.1 6.9 0.0 3.1 3 1 1 4 4 4 0 Protein of unknown function (DUF1664) DUF59 PF01883.14 CBZ51416.1 - 0.0015 18.4 0.0 0.5 10.3 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function DUF59 DUF769 PF05590.6 CBZ51416.1 - 0.12 11.5 0.0 0.2 10.8 0.0 1.3 1 0 0 1 1 1 0 Xylella fastidiosa protein of unknown function (DUF769) RRM_1 PF00076.17 CBZ51417.1 - 1.3e-14 53.5 0.0 2.2e-14 52.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBZ51417.1 - 3.4e-12 46.0 0.0 5.5e-12 45.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBZ51417.1 - 1.4e-11 44.1 0.0 3e-11 43.1 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RNase_PH PF01138.16 CBZ51418.1 - 3.7e-23 82.2 0.0 6.6e-23 81.4 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 AP2 PF00847.15 CBZ51419.1 - 8.6e-10 38.6 2.1 2e-09 37.4 1.5 1.6 1 0 0 1 1 1 1 AP2 domain GCD14 PF08704.5 CBZ51420.1 - 3.8e-64 216.5 0.0 6.8e-39 133.8 0.0 3.1 3 0 0 3 3 3 3 tRNA methyltransferase complex GCD14 subunit Methyltransf_18 PF12847.2 CBZ51420.1 - 0.0057 17.2 0.0 0.014 15.9 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 CBZ51420.1 - 0.0073 15.8 0.0 0.013 15.0 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) V-SNARE_C PF12352.3 CBZ51421.1 - 9.5e-07 28.7 1.4 2.4e-06 27.5 0.9 1.7 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.8 CBZ51421.1 - 0.00012 21.6 1.2 0.00019 21.0 0.2 1.8 2 0 0 2 2 2 1 Sec20 SNARE PF05739.14 CBZ51421.1 - 0.0055 16.3 4.0 0.0055 16.3 2.7 2.6 2 0 0 2 2 2 1 SNARE domain Baculo_PEP_C PF04513.7 CBZ51421.1 - 0.035 13.9 6.5 0.16 11.8 0.5 2.2 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1514 PF07438.6 CBZ51421.1 - 0.64 9.9 0.0 0.64 9.9 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1514) YtxH PF12732.2 CBZ51421.1 - 0.99 9.8 6.1 0.27 11.6 0.6 2.5 2 1 0 2 2 2 0 YtxH-like protein V-SNARE PF05008.10 CBZ51421.1 - 2.7 8.2 11.9 0.066 13.3 2.0 2.7 2 1 1 3 3 3 0 Vesicle transport v-SNARE protein N-terminus NPV_P10 PF05531.7 CBZ51421.1 - 2.8 8.2 7.9 11 6.3 0.4 2.9 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein FadA PF09403.5 CBZ51421.1 - 5.2 7.0 13.0 0.37 10.8 2.7 2.4 2 1 0 2 2 2 0 Adhesion protein FadA AlkA_N PF06029.6 CBZ51422.1 - 0.045 13.8 0.0 0.082 12.9 0.0 1.4 1 0 0 1 1 1 0 AlkA N-terminal domain PseudoU_synth_2 PF00849.17 CBZ51423.1 - 2.3e-17 63.3 0.0 4e-17 62.5 0.0 1.4 1 0 0 1 1 1 1 RNA pseudouridylate synthase MATH PF00917.21 CBZ51423.1 - 0.00013 22.1 0.1 0.00026 21.2 0.1 1.5 1 0 0 1 1 1 1 MATH domain USP7_ICP0_bdg PF12436.3 CBZ51423.1 - 0.48 9.6 0.0 0.79 8.9 0.0 1.2 1 0 0 1 1 1 0 ICP0-binding domain of Ubiquitin-specific protease 7 DIX PF00778.12 CBZ51424.1 - 0.00056 19.5 0.1 0.0057 16.3 0.1 2.1 1 1 0 1 1 1 1 DIX domain Pribosyltran_N PF13793.1 CBZ51425.1 - 6.6e-47 158.0 2.2 1.1e-45 154.0 0.0 2.6 3 0 0 3 3 3 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.1 CBZ51425.1 - 1.2e-32 113.1 0.2 2.5e-32 112.1 0.1 1.5 1 0 0 1 1 1 1 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 CBZ51425.1 - 3.4e-12 46.1 0.2 2.5e-11 43.3 0.0 2.2 2 0 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.1 CBZ51425.1 - 0.0032 16.7 0.0 0.0054 15.9 0.0 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase eIF-3c_N PF05470.7 CBZ51426.1 - 9.7 4.1 8.1 15 3.4 5.6 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus AP-5_subunit_s1 PF15001.1 CBZ51427.1 - 4e-29 101.8 0.0 5.2e-24 85.2 0.1 2.1 2 0 0 2 2 2 2 AP-5 complex subunit sigma-1 Macoilin PF09726.4 CBZ51428.1 - 6.9 4.8 2.8 16 3.6 2.0 1.5 1 0 0 1 1 1 0 Transmembrane protein EF-hand_7 PF13499.1 CBZ51429.1 - 1.9e-20 72.7 0.8 3.8e-11 42.9 0.0 2.5 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 CBZ51429.1 - 2e-18 64.5 1.4 2.4e-07 30.0 0.2 3.9 4 0 0 4 4 4 3 EF-hand domain EF-hand_1 PF00036.27 CBZ51429.1 - 1.6e-17 61.3 3.1 3.1e-07 29.1 0.0 4.2 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.1 CBZ51429.1 - 4.9e-16 58.0 2.1 3.3e-08 33.0 0.0 3.8 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.1 CBZ51429.1 - 1.2e-08 33.9 4.1 3.6e-06 26.0 0.1 3.7 4 0 0 4 4 4 1 EF hand EF-hand_9 PF14658.1 CBZ51429.1 - 2.7e-05 23.9 0.1 0.00068 19.5 0.0 2.5 2 1 0 2 2 2 1 EF-hand domain EFhand_Ca_insen PF08726.5 CBZ51429.1 - 0.029 14.3 0.0 0.11 12.4 0.0 1.9 2 0 0 2 2 2 0 Ca2+ insensitive EF hand Caleosin PF05042.8 CBZ51429.1 - 0.079 12.5 0.0 2 7.9 0.0 2.3 2 0 0 2 2 2 0 Caleosin related protein Ribosomal_L16 PF00252.13 CBZ51430.1 - 3e-21 75.5 0.0 4e-21 75.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e WD40 PF00400.27 CBZ51431.1 - 0.0011 18.7 1.7 0.029 14.2 0.1 3.6 3 0 0 3 3 3 1 WD domain, G-beta repeat CPSF_A PF03178.10 CBZ51431.1 - 0.0088 15.1 0.0 0.52 9.3 0.0 2.1 2 0 0 2 2 2 2 CPSF A subunit region DUF2052 PF09747.4 CBZ51432.1 - 1.1e-26 93.8 6.8 6e-15 55.6 3.7 4.0 3 2 0 3 3 3 2 Coiled-coil domain containing protein (DUF2052) Calc_CGRP_IAPP PF00214.14 CBZ51433.1 - 8.3 6.4 8.2 0.44 10.6 1.0 2.3 3 0 0 3 3 3 0 Calcitonin / CGRP / IAPP family SNARE PF05739.14 CBZ51434.1 - 0.0067 16.0 0.8 0.0067 16.0 0.6 2.4 3 0 0 3 3 3 1 SNARE domain Serine_rich PF08824.5 CBZ51434.1 - 0.022 14.4 2.4 0.24 11.1 0.4 2.6 3 0 0 3 3 3 0 Serine rich protein interaction domain Bcr-Abl_Oligo PF09036.5 CBZ51434.1 - 0.043 13.7 0.0 0.15 12.0 0.0 1.9 1 0 0 1 1 1 0 Bcr-Abl oncoprotein oligomerisation domain Rrn6 PF10214.4 CBZ51434.1 - 0.16 9.9 4.7 0.59 8.1 1.9 2.2 2 0 0 2 2 2 0 RNA polymerase I-specific transcription-initiation factor Synaptobrevin PF00957.16 CBZ51434.1 - 0.36 10.4 4.2 0.13 11.9 0.4 2.2 2 1 0 2 2 2 0 Synaptobrevin PseudoU_synth_1 PF01416.15 CBZ51437.1 - 6.1e-23 81.2 0.0 1.7e-16 60.5 0.0 3.4 2 1 1 3 3 3 3 tRNA pseudouridine synthase Herpes_DNAp_acc PF04929.7 CBZ51437.1 - 1.5 7.7 8.2 0.05 12.5 0.6 2.0 2 0 0 2 2 2 0 Herpes DNA replication accessory factor LRR_6 PF13516.1 CBZ51438.1 - 6.4e-13 47.3 0.6 0.59 10.3 0.0 7.7 8 0 0 8 8 8 3 Leucine Rich repeat LRR_1 PF00560.28 CBZ51438.1 - 3.7e-08 32.3 11.8 0.073 13.1 0.0 7.8 8 1 1 9 9 9 3 Leucine Rich Repeat LRR_4 PF12799.2 CBZ51438.1 - 6e-07 28.9 14.7 3.8e-06 26.3 0.2 5.0 4 1 1 5 5 5 2 Leucine Rich repeats (2 copies) LRR_7 PF13504.1 CBZ51438.1 - 3.6e-05 23.2 12.9 0.5 10.7 0.2 7.7 8 0 0 8 8 8 1 Leucine rich repeat LRR_8 PF13855.1 CBZ51438.1 - 0.00031 20.4 0.8 0.00031 20.4 0.6 4.7 5 1 1 6 6 6 1 Leucine rich repeat Voldacs PF03517.8 CBZ51440.1 - 1.2e-34 119.0 0.0 1.8e-34 118.4 0.0 1.3 1 0 0 1 1 1 1 Regulator of volume decrease after cellular swelling T4-Gluco-transf PF09198.5 CBZ51440.1 - 0.15 11.3 0.0 0.26 10.6 0.0 1.4 1 0 0 1 1 1 0 Bacteriophage T4 beta-glucosyltransferase IMCp PF12314.3 CBZ51442.1 - 0.0014 18.7 50.6 0.014 15.5 18.6 4.2 1 1 3 4 4 4 2 Inner membrane complex protein PapD-like PF14874.1 CBZ51444.1 - 2.6e-11 43.3 0.2 6.2e-06 26.0 0.0 4.4 4 0 0 4 4 4 3 Flagellar-associated PapD-like ABM PF03992.11 CBZ51444.1 - 0.0009 19.2 0.1 0.0024 17.8 0.1 1.8 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase Ribosomal_L18e PF00828.14 CBZ51445.1 - 3.4e-11 43.6 0.4 5.4e-10 39.7 0.0 2.9 2 1 0 2 2 2 1 Ribosomal protein L18e/L15 BSD PF03909.12 CBZ51446.1 - 6.2e-15 54.6 0.0 1e-14 53.9 0.0 1.2 1 0 0 1 1 1 1 BSD domain PrgI PF12666.2 CBZ51447.1 - 0.086 12.9 1.4 0.26 11.4 0.9 1.8 1 0 0 1 1 1 0 PrgI family protein tRNA-synt_2 PF00152.15 CBZ51448.1 - 6.3e-50 169.8 0.0 4e-23 81.7 0.0 3.5 3 1 0 3 3 3 3 tRNA synthetases class II (D, K and N) Solute_trans_a PF03619.11 CBZ51448.1 - 2.4e-40 138.5 15.2 6.8e-20 71.5 2.1 3.2 3 0 0 3 3 3 3 Organic solute transporter Ostalpha tRNA-synt_2d PF01409.15 CBZ51448.1 - 0.00013 21.2 0.0 0.05 12.8 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) tRNA_anti-codon PF01336.20 CBZ51448.1 - 0.059 13.2 0.0 0.66 9.8 0.0 2.1 1 1 0 1 1 1 0 OB-fold nucleic acid binding domain FAD_binding_3 PF01494.14 CBZ51449.1 - 1.9e-58 198.2 0.0 2.1e-31 109.3 0.0 3.3 3 0 0 3 3 3 3 FAD binding domain FAD_binding_2 PF00890.19 CBZ51449.1 - 0.0012 17.7 0.1 0.0027 16.6 0.1 1.6 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 CBZ51449.1 - 0.0023 17.8 0.0 0.0039 17.0 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 CBZ51449.1 - 0.0043 17.0 0.0 0.025 14.5 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 CBZ51449.1 - 0.0073 15.2 0.1 0.013 14.4 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.1 CBZ51449.1 - 0.072 13.1 0.1 0.21 11.5 0.0 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 CBZ51449.1 - 0.086 11.9 0.1 0.15 11.1 0.0 1.2 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.9 CBZ51449.1 - 0.15 10.5 0.1 0.21 10.0 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein UDPG_MGDP_dh_N PF03721.9 CBZ51449.1 - 0.17 11.2 0.1 0.3 10.4 0.1 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DUF1183 PF06682.7 CBZ51449.1 - 0.4 10.2 11.0 3.4 7.1 5.9 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1183) 3HCDH_N PF02737.13 CBZ51449.1 - 0.49 10.0 0.0 0.81 9.3 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Spc7 PF08317.6 CBZ51450.1 - 0.019 13.6 17.9 0.029 13.0 6.5 2.4 2 0 0 2 2 2 0 Spc7 kinetochore protein Cytochrom_B_N_2 PF13631.1 CBZ51452.1 - 0.061 13.1 0.9 0.11 12.3 0.6 1.3 1 0 0 1 1 1 0 Cytochrome b(N-terminal)/b6/petB Cofilin_ADF PF00241.15 CBZ51453.1 - 7.2e-29 100.2 0.0 8.9e-29 99.9 0.0 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein PDEase_I PF00233.14 CBZ51454.1 - 1.5e-31 109.9 2.4 2.2e-31 109.4 1.7 1.2 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase CKS PF01111.14 CBZ51456.1 - 4.1e-18 64.9 0.1 6.2e-18 64.3 0.1 1.3 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit RNase_H PF00075.19 CBZ51457.1 - 2.2e-19 70.1 0.0 1.6e-08 34.9 0.0 3.2 2 1 0 2 2 2 2 RNase H Snf7 PF03357.16 CBZ51458.1 - 8.2e-07 28.5 9.5 1.7e-06 27.4 4.4 2.0 1 1 1 2 2 2 2 Snf7 Gly_rich_SFCGS PF14272.1 CBZ51459.1 - 0.071 12.9 0.1 0.21 11.4 0.1 1.7 1 0 0 1 1 1 0 Glycine-rich SFCGS KH_1 PF00013.24 CBZ51461.1 - 0.00017 21.1 0.1 0.0006 19.4 0.0 1.9 2 0 0 2 2 2 1 KH domain FlhE PF06366.8 CBZ51461.1 - 0.02 14.7 0.1 5 7.0 0.0 2.5 2 0 0 2 2 2 0 Flagellar protein FlhE SEP PF08059.8 CBZ51462.1 - 3.6e-24 84.8 0.0 6.3e-24 84.0 0.0 1.4 1 0 0 1 1 1 1 SEP domain UBX PF00789.15 CBZ51462.1 - 1.5e-14 53.7 0.0 2.2e-14 53.2 0.0 1.3 1 0 0 1 1 1 1 UBX domain Hid1 PF12722.2 CBZ51463.1 - 0.088 10.4 11.6 0.12 10.0 8.0 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein POP1 PF06978.6 CBZ51463.1 - 0.22 11.1 12.5 0.57 9.8 8.7 1.8 1 0 0 1 1 1 0 Ribonucleases P/MRP protein subunit POP1 HAUS6_N PF14661.1 CBZ51463.1 - 8.1 5.7 24.4 4.7 6.4 14.1 2.3 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus AP2 PF00847.15 CBZ51464.1 - 4.9e-07 29.8 0.5 0.004 17.2 0.0 2.6 2 0 0 2 2 2 2 AP2 domain TLP-20 PF06088.6 CBZ51464.1 - 4.8 6.8 5.6 15 5.2 3.9 1.9 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) TauE PF01925.14 CBZ51465.1 - 1.3e-13 50.9 1.9 2.5e-13 50.0 1.3 1.4 1 0 0 1 1 1 1 Sulfite exporter TauE/SafE TMEM18 PF14770.1 CBZ51465.1 - 0.17 11.3 2.7 0.3 10.6 0.1 2.6 3 0 0 3 3 3 0 Transmembrane protein 18 zf-C3HC4_3 PF13920.1 CBZ51466.1 - 1.1e-12 47.4 11.1 1.8e-12 46.6 7.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CBZ51466.1 - 0.0004 20.3 15.0 0.00067 19.6 10.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CBZ51466.1 - 0.013 15.2 14.5 0.023 14.5 10.1 1.4 1 0 0 1 1 1 0 Ring finger domain Prok-RING_4 PF14447.1 CBZ51466.1 - 0.11 12.0 6.2 0.2 11.1 4.3 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_4 PF14570.1 CBZ51466.1 - 0.13 11.8 10.7 0.27 10.8 7.4 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain MFS_1 PF07690.11 CBZ51468.1 - 1.7e-10 40.1 14.8 4e-06 25.7 2.3 3.3 2 1 1 3 3 3 3 Major Facilitator Superfamily Ycf1 PF05758.7 CBZ51468.1 - 0.027 12.2 0.0 0.034 11.8 0.0 1.1 1 0 0 1 1 1 0 Ycf1 DUF3487 PF11990.3 CBZ51468.1 - 0.2 11.0 0.0 0.2 11.0 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3487) PP2C PF00481.16 CBZ51469.1 - 4e-42 144.3 0.1 1.9e-31 109.4 0.0 3.2 3 0 0 3 3 3 3 Protein phosphatase 2C SAG PF04092.8 CBZ51469.1 - 8.7e-13 48.7 7.3 1.8e-06 28.3 1.7 2.5 2 0 0 2 2 2 2 SRS domain PP2C_2 PF13672.1 CBZ51469.1 - 0.0017 17.7 0.0 0.018 14.4 0.0 2.4 2 1 0 2 2 2 1 Protein phosphatase 2C SAG PF04092.8 CBZ51470.1 - 2.8e-15 56.7 16.0 1.7e-07 31.6 4.3 2.5 2 1 0 2 2 2 2 SRS domain HemeBinding_Shp PF11545.3 CBZ51470.1 - 0.0057 16.4 0.7 0.049 13.4 0.0 2.4 1 1 1 2 2 2 1 Cell surface heme-binding protein Shp SCF PF02404.10 CBZ51471.1 - 5 6.2 2.1 10 5.2 1.4 1.4 1 0 0 1 1 1 0 Stem cell factor Cpn60_TCP1 PF00118.19 CBZ51473.1 - 1.6e-118 396.4 0.8 1.8e-118 396.2 0.5 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family SAG PF04092.8 CBZ51474.1 - 3.8e-55 185.5 16.4 3.7e-28 98.3 2.3 2.2 2 0 0 2 2 2 2 SRS domain SAG PF04092.8 CBZ51475.1 - 3.3e-50 169.6 13.6 1.2e-27 96.7 2.0 2.2 2 0 0 2 2 2 2 SRS domain SAG PF04092.8 CBZ51476.1 - 1e-51 174.5 12.7 4.2e-28 98.2 1.8 2.1 2 0 0 2 2 2 2 SRS domain SAG PF04092.8 CBZ51477.1 - 8.1e-51 171.5 14.4 3.2e-27 95.3 1.1 2.1 2 0 0 2 2 2 2 SRS domain Fer4_NifH PF00142.13 CBZ51477.1 - 0.065 12.4 0.0 0.2 10.8 0.0 1.8 2 0 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family PNTB PF02233.11 CBZ51478.1 - 1.6e-168 561.2 16.2 1.6e-168 561.2 11.2 1.8 2 0 0 2 2 2 1 NAD(P) transhydrogenase beta subunit AlaDh_PNT_C PF01262.16 CBZ51478.1 - 2.9e-46 157.1 0.1 5.5e-46 156.1 0.1 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain DUF3814 PF12769.2 CBZ51478.1 - 1.1e-27 96.0 6.4 1.1e-27 96.0 4.4 4.3 3 2 1 4 4 4 1 Domain of unknown function (DUF3814) AlaDh_PNT_N PF05222.10 CBZ51478.1 - 1.6e-23 83.1 0.7 9.9e-18 64.4 0.0 3.2 4 0 0 4 4 4 2 Alanine dehydrogenase/PNT, N-terminal domain Pyr_redox_2 PF07992.9 CBZ51478.1 - 0.014 15.3 0.8 0.14 12.0 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 CBZ51478.1 - 0.015 15.4 0.2 1.5 8.9 0.0 2.9 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.14 CBZ51478.1 - 0.05 12.7 0.1 9.7 5.3 0.0 2.6 3 0 0 3 3 3 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain CPSase_L_chain PF00289.17 CBZ51478.1 - 0.058 13.5 0.1 9.6 6.3 0.1 2.7 2 0 0 2 2 2 0 Carbamoyl-phosphate synthase L chain, N-terminal domain Exo_endo_phos PF03372.18 CBZ51479.1 - 1.4e-08 34.9 0.0 3.6e-08 33.6 0.0 1.6 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family CDC45 PF02724.9 CBZ51479.1 - 0.00016 19.8 9.4 0.00016 19.8 6.5 1.4 2 0 0 2 2 2 1 CDC45-like protein Ycf1 PF05758.7 CBZ51479.1 - 0.0011 16.8 1.6 0.0013 16.5 1.1 1.1 1 0 0 1 1 1 1 Ycf1 Spore_coat_CotO PF14153.1 CBZ51479.1 - 0.0029 17.0 8.6 0.0029 17.0 6.0 1.6 2 0 0 2 2 2 1 Spore coat protein CotO Tim54 PF11711.3 CBZ51479.1 - 0.11 11.0 9.7 0.2 10.2 6.7 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 SAPS PF04499.10 CBZ51479.1 - 0.13 10.8 3.4 0.23 10.0 2.4 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein TRAP_alpha PF03896.11 CBZ51479.1 - 0.25 10.2 14.6 0.5 9.3 10.1 1.4 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit YqfQ PF14181.1 CBZ51479.1 - 1.6 8.7 12.4 4.1 7.4 8.6 1.6 1 0 0 1 1 1 0 YqfQ-like protein RRN3 PF05327.6 CBZ51479.1 - 2.8 5.9 16.2 4.3 5.3 11.3 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DUF3530 PF12048.3 CBZ51479.1 - 9.1 5.1 8.9 14 4.5 6.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) BHD_1 PF10403.4 CBZ51480.1 - 5.6e-12 45.0 0.0 9e-12 44.3 0.0 1.3 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_3 PF10405.4 CBZ51480.1 - 5.8e-10 38.7 0.0 5.8e-09 35.5 0.0 2.1 1 1 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_2 PF10404.4 CBZ51480.1 - 1.1e-08 35.2 1.4 1.1e-08 35.2 1.0 3.4 2 1 0 2 2 2 1 Rad4 beta-hairpin domain 2 Rad4 PF03835.10 CBZ51480.1 - 1.1e-06 28.0 0.1 3.3e-06 26.5 0.0 1.7 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain Tropomyosin_1 PF12718.2 CBZ51481.1 - 0.00016 21.5 7.8 0.00016 21.5 5.4 2.3 2 0 0 2 2 2 1 Tropomyosin like IncA PF04156.9 CBZ51481.1 - 0.0064 16.0 11.9 0.0083 15.7 1.5 2.5 2 0 0 2 2 2 1 IncA protein DUF4570 PF15134.1 CBZ51481.1 - 0.039 13.7 0.3 0.039 13.7 0.2 2.5 3 0 0 3 3 2 0 Domain of unknown function (DUF4570) DUF4200 PF13863.1 CBZ51481.1 - 0.039 13.8 18.3 0.65 9.9 5.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) Syntaxin-6_N PF09177.6 CBZ51481.1 - 0.048 14.0 8.9 0.78 10.1 0.6 3.1 2 1 0 2 2 2 0 Syntaxin 6, N-terminal BLOC1_2 PF10046.4 CBZ51481.1 - 0.076 13.1 7.4 2 8.5 0.3 2.5 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF1515 PF07439.6 CBZ51481.1 - 0.11 12.2 5.6 0.043 13.6 0.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1515) Reo_sigmaC PF04582.7 CBZ51481.1 - 0.25 10.4 2.1 0.57 9.2 0.3 2.1 2 0 0 2 2 2 0 Reovirus sigma C capsid protein GAS PF13851.1 CBZ51481.1 - 0.37 9.9 16.2 0.11 11.6 4.9 2.3 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding DUF972 PF06156.8 CBZ51481.1 - 1 9.7 6.6 4.3 7.7 0.1 2.8 2 1 2 4 4 4 0 Protein of unknown function (DUF972) DUF1664 PF07889.7 CBZ51481.1 - 1.2 8.9 3.4 8.7 6.1 0.7 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) Spectrin PF00435.16 CBZ51481.1 - 1.5 9.1 12.6 3.4 7.9 0.4 3.2 2 1 0 3 3 3 0 Spectrin repeat Surfac_D-trimer PF09006.6 CBZ51481.1 - 1.6 8.4 5.8 2.8 7.7 0.1 3.7 4 0 0 4 4 3 0 Lung surfactant protein D coiled-coil trimerisation Lzipper-MIP1 PF14389.1 CBZ51481.1 - 2 8.6 15.3 2.5 8.2 0.1 3.7 2 1 1 3 3 3 0 Leucine-zipper of ternary complex factor MIP1 APG6 PF04111.7 CBZ51481.1 - 2.3 7.1 18.5 1.2 8.0 1.9 2.1 2 0 0 2 2 2 0 Autophagy protein Apg6 KxDL PF10241.4 CBZ51481.1 - 2.5 8.0 8.1 2 8.3 0.6 2.8 2 1 1 3 3 3 0 Uncharacterized conserved protein DUF2353 PF09789.4 CBZ51481.1 - 2.5 7.2 13.4 0.48 9.6 4.1 2.0 2 0 0 2 2 2 0 Uncharacterized coiled-coil protein (DUF2353) TBPIP PF07106.8 CBZ51481.1 - 3.1 7.3 11.0 2.3 7.7 0.4 2.8 2 1 1 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Laminin_II PF06009.7 CBZ51481.1 - 4.5 7.0 9.3 3.6 7.3 0.5 3.1 2 1 1 3 3 3 0 Laminin Domain II TMF_TATA_bd PF12325.3 CBZ51482.1 - 0.028 14.1 8.1 0.037 13.7 5.0 1.6 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding TMF_DNA_bd PF12329.3 CBZ51482.1 - 0.087 12.6 7.0 0.24 11.2 4.9 1.7 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Atg14 PF10186.4 CBZ51482.1 - 0.25 10.2 9.2 0.46 9.3 6.4 1.4 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF1640 PF07798.6 CBZ51482.1 - 0.4 10.7 5.4 0.67 9.9 3.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) ADIP PF11559.3 CBZ51482.1 - 5.1 6.9 12.3 4.2 7.2 7.0 1.9 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Pkinase PF00069.20 CBZ51483.1 - 1.3e-34 119.5 0.0 1e-30 106.7 0.0 2.8 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ51483.1 - 3.4e-23 82.0 0.0 1.1e-20 73.8 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase EDR1 PF14381.1 CBZ51483.1 - 1.8e-14 53.8 0.0 4.4e-14 52.5 0.0 1.6 1 0 0 1 1 1 1 Ethylene-responsive protein kinase Le-CTR1 LRR_4 PF12799.2 CBZ51483.1 - 0.003 17.1 11.3 0.49 10.0 0.1 4.6 5 0 0 5 5 5 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 CBZ51483.1 - 0.008 16.1 9.8 5.5 7.3 0.0 6.7 7 0 0 7 7 7 1 Leucine Rich repeat Pox_ser-thr_kin PF05445.6 CBZ51483.1 - 3.5 6.3 0.0 5.2 5.7 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase LRR_7 PF13504.1 CBZ51483.1 - 7.2 7.2 10.0 56 4.6 0.0 5.7 6 0 0 6 6 6 0 Leucine rich repeat Gtr1_RagA PF04670.7 CBZ51484.1 - 8.8e-27 93.7 0.0 1.9e-20 72.9 0.0 2.7 2 1 0 2 2 2 2 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 CBZ51484.1 - 0.13 12.1 0.0 1.3 8.9 0.0 2.2 1 1 0 1 1 1 0 50S ribosome-binding GTPase RNA_GG_bind PF10258.4 CBZ51485.1 - 2e-17 62.6 0.0 4.8e-17 61.4 0.0 1.6 1 0 0 1 1 1 1 PHAX RNA-binding domain SLD3 PF08639.5 CBZ51485.1 - 0.25 9.9 8.3 0.4 9.2 5.8 1.3 1 0 0 1 1 1 0 DNA replication regulator SLD3 DnaJ PF00226.26 CBZ51486.1 - 3.2e-24 84.4 0.4 9.4e-24 82.9 0.3 1.9 1 0 0 1 1 1 1 DnaJ domain zf-met PF12874.2 CBZ51486.1 - 6.3e-09 35.7 3.4 1.7e-07 31.1 0.2 2.5 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 CBZ51486.1 - 1.7e-08 34.3 4.3 1.8e-06 27.8 0.5 2.5 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 CBZ51486.1 - 4.4e-06 26.7 3.1 0.015 15.3 0.0 3.1 3 0 0 3 3 3 2 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.1 CBZ51486.1 - 8.7e-06 25.7 3.4 0.025 14.8 0.1 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 CBZ51486.1 - 1.7e-05 24.8 2.3 0.13 12.6 0.2 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 CBZ51486.1 - 3e-05 23.7 2.7 0.2 11.5 0.3 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger TFIIA PF03153.8 CBZ51486.1 - 0.0069 16.3 15.0 0.0069 16.3 10.4 2.3 2 0 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit zf-DBF PF07535.7 CBZ51486.1 - 0.2 11.3 3.6 0.4 10.3 0.8 2.5 2 0 0 2 2 2 0 DBF zinc finger Zn-ribbon_8 PF09723.5 CBZ51486.1 - 0.29 11.1 2.6 12 5.9 0.1 2.8 2 0 0 2 2 2 0 Zinc ribbon domain SNARE_assoc PF09335.6 CBZ51487.1 - 2.7e-16 59.8 5.1 2.7e-16 59.8 3.5 2.4 3 0 0 3 3 3 1 SNARE associated Golgi protein zf-DHHC PF01529.15 CBZ51488.1 - 9.8e-08 31.5 5.7 9.8e-08 31.5 3.9 2.6 3 1 0 3 3 3 1 DHHC palmitoyltransferase DUF221 PF02714.10 CBZ51488.1 - 3.2e-05 22.9 20.2 0.0014 17.6 0.1 4.1 4 1 0 4 4 4 3 Domain of unknown function DUF221 EFG_C PF00679.19 CBZ51488.1 - 7.4e-05 22.5 0.0 0.00017 21.3 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G C-terminus MORN PF02493.15 CBZ51489.1 - 4.8e-50 164.4 70.3 1.5e-06 27.5 0.9 10.1 10 0 0 10 10 10 9 MORN repeat Form_Nir_trans PF01226.12 CBZ51490.1 - 2.6e-49 167.4 16.5 2.7e-25 88.6 1.0 2.1 1 1 1 2 2 2 2 Formate/nitrite transporter G-patch_2 PF12656.2 CBZ51490.1 - 0.17 11.7 0.0 0.32 10.8 0.0 1.3 1 0 0 1 1 1 0 DExH-box splicing factor binding site TrbC PF04956.8 CBZ51490.1 - 0.34 10.9 6.7 0.086 12.8 1.3 2.2 2 0 0 2 2 2 0 TrbC/VIRB2 family E1_dh PF00676.15 CBZ51491.1 - 4.3e-64 216.1 0.3 5.6e-64 215.7 0.2 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component tRNA-synt_1 PF00133.17 CBZ51492.1 - 8.9e-39 132.9 1.4 9.6e-16 56.8 0.2 3.9 3 1 0 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.6 CBZ51492.1 - 2e-20 72.8 0.6 3e-09 36.0 0.0 3.0 3 0 0 3 3 3 2 tRNA synthetases class I (M) tRNA-synt_1e PF01406.14 CBZ51492.1 - 9.5e-14 51.1 0.1 2.2e-12 46.7 0.0 2.5 3 0 0 3 3 3 1 tRNA synthetases class I (C) catalytic domain Anticodon_1 PF08264.8 CBZ51492.1 - 7.6e-13 48.4 0.1 2.2e-12 47.0 0.0 1.8 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA Pkinase PF00069.20 CBZ51493.1 - 2.4e-49 167.8 0.0 4.1e-18 65.4 0.0 3.2 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ51493.1 - 1.1e-24 86.8 0.0 8.4e-20 70.9 0.0 2.6 2 1 0 2 2 2 2 Protein tyrosine kinase EF-hand_1 PF00036.27 CBZ51493.1 - 9.9e-14 49.5 0.2 8.7e-06 24.6 0.0 3.8 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.1 CBZ51493.1 - 8.2e-10 38.6 1.4 0.0016 18.5 0.1 4.3 3 1 1 4 4 4 3 EF-hand domain pair EF-hand_6 PF13405.1 CBZ51493.1 - 1.6e-09 36.8 0.2 0.018 14.8 0.1 4.4 4 0 0 4 4 4 2 EF-hand domain EF-hand_8 PF13833.1 CBZ51493.1 - 1.4e-07 31.0 1.9 0.05 13.2 0.0 3.9 4 0 0 4 4 4 2 EF-hand domain pair EF-hand_5 PF13202.1 CBZ51493.1 - 3.8e-06 25.9 0.8 0.0054 16.0 0.0 3.4 3 0 0 3 3 3 1 EF hand GCC2_GCC3 PF07699.8 CBZ51495.1 - 7.6e-29 99.0 114.6 2.9e-09 36.3 4.9 11.5 10 1 1 11 11 11 7 GCC2 and GCC3 AAA_27 PF13514.1 CBZ51495.1 - 0.055 11.1 11.3 0.078 10.6 7.9 1.1 1 0 0 1 1 1 0 AAA domain UPF0137 PF03677.8 CBZ51495.1 - 1.1 8.7 0.2 1.9 7.9 0.2 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0137) Lipoprotein_20 PF13942.1 CBZ51495.1 - 3.8 7.0 0.3 7.2 6.1 0.2 1.4 1 0 0 1 1 1 0 YfhG lipoprotein DUF2627 PF11118.3 CBZ51495.1 - 5 7.3 0.0 14 5.8 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2627) Med3 PF11593.3 CBZ51495.1 - 5.2 6.2 3.2 13 4.8 2.2 1.6 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal RRXRR PF14239.1 CBZ51495.1 - 5.6 6.3 0.4 12 5.2 0.1 1.7 2 0 0 2 2 2 0 RRXRR protein DNA_pol3_a_NII PF11490.3 CBZ51495.1 - 6.5 6.4 2.7 12 5.4 1.9 1.3 1 0 0 1 1 1 0 DNA polymerase III polC-type N-terminus II SAM_1 PF00536.25 CBZ51495.1 - 8.5 6.6 0.0 19 5.5 0.0 1.5 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) TFIIB PF00382.14 CBZ51496.1 - 2.3e-15 56.1 1.6 8.5e-08 31.8 0.1 2.4 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.7 CBZ51496.1 - 7.4e-10 37.9 0.6 1.4e-09 37.1 0.4 1.5 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_C PF02984.14 CBZ51496.1 - 2.2e-06 27.5 0.0 0.00012 22.0 0.0 2.2 1 1 0 2 2 2 1 Cyclin, C-terminal domain mTERF PF02536.9 CBZ51497.1 - 8.2e-12 44.3 0.9 1.7e-11 43.3 0.6 1.4 1 0 0 1 1 1 1 mTERF HECT PF00632.20 CBZ51498.1 - 5.8e-68 229.3 0.0 9.3e-68 228.7 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) UME PF08064.8 CBZ51498.1 - 1.1 9.2 0.1 2.9 7.8 0.1 1.7 1 0 0 1 1 1 0 UME (NUC010) domain Kinase-like PF14531.1 CBZ51499.1 - 2.6e-19 69.2 0.0 3.8e-19 68.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like ubiquitin PF00240.18 CBZ51502.1 - 3.6e-10 39.0 0.0 5.4e-10 38.5 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 CBZ51502.1 - 0.0011 18.5 0.0 0.0016 18.0 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.1 CBZ51502.1 - 0.0014 18.4 0.0 0.0033 17.2 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 CBZ51502.1 - 0.016 15.3 0.0 0.035 14.2 0.0 1.5 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain zf-HIT PF04438.11 CBZ51503.1 - 2.1e-07 30.4 14.8 3.4e-07 29.7 10.3 1.4 1 0 0 1 1 1 1 HIT zinc finger DUF3866 PF12982.2 CBZ51503.1 - 0.077 11.9 0.2 0.22 10.4 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3866) Nucleo_P87 PF07267.6 CBZ51503.1 - 8.7 4.8 7.5 4.2 5.9 3.7 1.5 2 0 0 2 2 2 0 Nucleopolyhedrovirus capsid protein P87 PI31_Prot_C PF08577.6 CBZ51504.1 - 2.7e-07 31.1 14.5 2.7e-07 31.1 10.1 2.8 2 0 0 2 2 2 1 PI31 proteasome regulator EnY2 PF10163.4 CBZ51505.1 - 0.00014 21.6 0.2 0.00027 20.8 0.1 1.4 1 0 0 1 1 1 1 Transcription factor e(y)2 DASH_Dam1 PF08653.5 CBZ51506.1 - 0.88 9.3 0.2 1.4e+02 2.3 0.0 5.3 2 0 0 2 2 2 0 DASH complex subunit Dam1 SPX PF03105.14 CBZ51506.1 - 1.2 8.8 0.0 1.2 8.8 0.0 24.6 4 3 8 13 13 13 0 SPX domain MtrB PF05440.7 CBZ51506.1 - 3.1 7.9 0.1 86 3.2 0.1 3.6 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase subunit B CK_II_beta PF01214.13 CBZ51506.1 - 5.4 6.4 2.2 43 3.5 1.5 2.6 1 0 0 1 1 1 0 Casein kinase II regulatory subunit Rhomboid PF01694.17 CBZ51508.1 - 9.2e-28 97.0 8.7 1.6e-27 96.2 6.1 1.4 1 0 0 1 1 1 1 Rhomboid family DER1 PF04511.10 CBZ51508.1 - 1.2e-05 24.9 2.7 1.2e-05 24.9 1.9 1.5 1 1 0 1 1 1 1 Der1-like family MFS_Mycoplasma PF07672.8 CBZ51508.1 - 0.93 8.5 12.5 0.29 10.2 0.2 2.7 2 2 1 3 3 3 0 Mycoplasma MFS transporter DUF1751 PF08551.5 CBZ51508.1 - 3.9 7.8 11.5 0.056 13.7 1.0 2.7 2 1 2 4 4 4 0 Eukaryotic integral membrane protein (DUF1751) DUF996 PF06195.8 CBZ51508.1 - 9.1 6.2 8.6 0.47 10.4 0.7 2.5 1 1 1 3 3 3 0 Protein of unknown function (DUF996) NifU PF01106.12 CBZ51510.1 - 1.4e-18 66.4 0.1 2.2e-18 65.7 0.0 1.3 1 0 0 1 1 1 1 NifU-like domain Nfu_N PF08712.6 CBZ51510.1 - 5.1e-13 48.4 0.0 9.6e-13 47.5 0.0 1.4 1 0 0 1 1 1 1 Scaffold protein Nfu/NifU N terminal DUF1032 PF06278.6 CBZ51512.1 - 1.7e-06 26.8 2.2 0.015 13.8 0.0 3.4 3 0 0 3 3 3 3 Protein of unknown function (DUF1032) Arf PF00025.16 CBZ51513.1 - 8.2e-48 161.9 1.7 8.4e-47 158.6 0.1 1.9 1 1 1 2 2 2 1 ADP-ribosylation factor family Ras PF00071.17 CBZ51513.1 - 2.6e-07 30.1 0.0 3e-07 29.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.7 CBZ51513.1 - 5.1e-07 29.0 0.0 6.1e-07 28.8 0.0 1.0 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.15 CBZ51513.1 - 1.2e-05 24.1 0.4 1.6e-05 23.8 0.3 1.3 1 1 0 1 1 1 1 G-protein alpha subunit GTP_EFTU PF00009.22 CBZ51513.1 - 4.1e-05 23.0 0.0 5e-05 22.8 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 CBZ51513.1 - 0.00021 20.5 0.0 0.00027 20.2 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Miro PF08477.8 CBZ51513.1 - 0.0048 17.3 0.0 0.007 16.8 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein CENP-F_leu_zip PF10473.4 CBZ51514.1 - 0.00034 20.4 4.2 0.00034 20.4 2.9 2.3 1 1 0 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 bZIP_1 PF00170.16 CBZ51514.1 - 0.0068 16.3 5.4 1.3 9.0 0.1 3.7 2 1 1 3 3 3 1 bZIP transcription factor Filament PF00038.16 CBZ51514.1 - 0.025 14.0 11.6 0.029 13.8 3.3 2.4 1 1 1 2 2 2 0 Intermediate filament protein SlyX PF04102.7 CBZ51514.1 - 0.045 14.1 1.3 0.045 14.1 0.9 3.9 1 1 2 4 4 4 0 SlyX CENP-H PF05837.7 CBZ51514.1 - 0.046 13.9 8.0 1.3 9.2 1.5 3.3 2 2 1 3 3 3 0 Centromere protein H (CENP-H) HOOK PF05622.7 CBZ51514.1 - 0.051 11.3 9.4 0.027 12.3 2.8 2.1 1 1 1 2 2 2 0 HOOK protein DUF972 PF06156.8 CBZ51514.1 - 0.055 13.8 9.8 0.063 13.6 1.1 3.4 1 1 2 3 3 3 0 Protein of unknown function (DUF972) GAS PF13851.1 CBZ51514.1 - 0.062 12.4 7.6 6.9 5.8 5.1 2.4 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding CCDC155 PF14662.1 CBZ51514.1 - 0.084 12.4 13.8 0.32 10.5 2.7 2.4 1 1 0 2 2 2 0 Coiled-coil region of CCDC155 APG6 PF04111.7 CBZ51514.1 - 0.11 11.4 8.1 0.95 8.4 5.6 2.0 1 1 0 1 1 1 0 Autophagy protein Apg6 BLOC1_2 PF10046.4 CBZ51514.1 - 0.13 12.4 2.7 0.35 11.0 0.3 2.4 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 PspA_IM30 PF04012.7 CBZ51514.1 - 0.19 11.0 14.0 0.77 9.0 0.9 2.9 1 1 2 3 3 3 0 PspA/IM30 family HR1 PF02185.11 CBZ51514.1 - 0.2 11.4 12.9 0.19 11.5 0.5 3.8 4 0 0 4 4 4 0 Hr1 repeat HALZ PF02183.13 CBZ51514.1 - 0.24 11.1 11.2 0.13 11.9 0.9 4.1 1 1 3 4 4 4 0 Homeobox associated leucine zipper TEX13 PF15186.1 CBZ51514.1 - 0.24 10.9 5.2 0.22 11.0 1.2 2.4 1 1 1 2 2 2 0 Testis-expressed sequence 13 protein family TMCO5 PF14992.1 CBZ51514.1 - 0.3 10.1 5.9 0.3 10.2 2.8 1.9 2 0 0 2 2 2 0 TMCO5 family Reo_sigmaC PF04582.7 CBZ51514.1 - 0.51 9.4 5.3 0.28 10.3 0.8 2.3 1 1 2 3 3 3 0 Reovirus sigma C capsid protein G-gamma PF00631.17 CBZ51514.1 - 0.63 9.8 3.3 4.6 7.0 0.1 3.2 3 1 0 3 3 3 0 GGL domain TBPIP PF07106.8 CBZ51514.1 - 1.3 8.4 9.7 3.7 7.0 0.9 3.1 1 1 3 4 4 4 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Spc7 PF08317.6 CBZ51514.1 - 1.4 7.4 8.1 0.69 8.5 3.4 1.7 1 1 0 1 1 1 0 Spc7 kinetochore protein Spectrin PF00435.16 CBZ51514.1 - 2.5 8.4 7.8 9.5 6.5 2.9 2.4 1 1 1 2 2 2 0 Spectrin repeat TMF_DNA_bd PF12329.3 CBZ51514.1 - 3.1 7.6 12.7 9.3 6.1 1.6 4.0 3 1 1 4 4 4 0 TATA element modulatory factor 1 DNA binding DUF904 PF06005.7 CBZ51514.1 - 3.6 7.9 12.1 8.2e+02 0.3 6.2 3.9 2 1 0 2 2 2 0 Protein of unknown function (DUF904) Mod_r PF07200.8 CBZ51514.1 - 5.7 6.8 11.9 0.27 11.1 1.3 2.6 2 1 1 3 3 2 0 Modifier of rudimentary (Mod(r)) protein NYD-SP28_assoc PF14775.1 CBZ51514.1 - 7.5 6.3 7.5 29 4.4 0.4 3.3 2 1 1 3 3 3 0 Sperm tail C-terminal domain Atg14 PF10186.4 CBZ51514.1 - 8.6 5.2 10.0 4.4 6.1 4.2 2.2 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 IncA PF04156.9 CBZ51514.1 - 9.3 5.7 13.7 5.5 6.5 7.7 1.9 1 1 1 2 2 2 0 IncA protein Pkinase PF00069.20 CBZ51515.1 - 3.2e-06 26.4 0.0 1.3e-05 24.4 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain EF-hand_8 PF13833.1 CBZ51515.1 - 0.0001 21.8 0.1 0.00038 20.0 0.0 2.0 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_7 PF13499.1 CBZ51515.1 - 0.0002 21.3 0.0 0.19 11.8 0.0 2.5 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_9 PF14658.1 CBZ51515.1 - 0.0071 16.2 0.0 1.8 8.5 0.0 2.6 2 1 0 2 2 2 2 EF-hand domain EF-hand_6 PF13405.1 CBZ51515.1 - 0.045 13.6 0.0 9.3 6.4 0.1 2.9 2 0 0 2 2 2 0 EF-hand domain Pkinase PF00069.20 CBZ51516.1 - 3.6e-07 29.6 0.0 0.00058 19.0 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ51516.1 - 0.11 11.5 0.0 0.23 10.5 0.0 1.5 1 0 0 1 1 1 0 Protein tyrosine kinase KH_1 PF00013.24 CBZ51517.1 - 1.6e-18 66.0 0.1 6.1e-08 32.2 0.0 2.4 2 0 0 2 2 2 2 KH domain KH_3 PF13014.1 CBZ51517.1 - 3.7e-11 42.4 0.2 2e-05 24.1 0.0 2.5 2 0 0 2 2 2 2 KH domain KH_2 PF07650.12 CBZ51517.1 - 0.002 17.6 0.3 0.22 11.0 0.0 2.4 2 0 0 2 2 2 2 KH domain KH_4 PF13083.1 CBZ51517.1 - 0.13 11.9 0.6 16 5.2 0.1 2.5 2 0 0 2 2 2 0 KH domain Choline_transpo PF04515.7 CBZ51518.1 - 7.4e-37 126.8 20.4 7.4e-37 126.8 14.2 1.6 2 0 0 2 2 2 1 Plasma-membrane choline transporter E1-E2_ATPase PF00122.15 CBZ51518.1 - 5.1 6.0 5.5 16 4.4 3.8 1.8 1 0 0 1 1 1 0 E1-E2 ATPase DNA_pol3_delta2 PF13177.1 CBZ51519.1 - 1.6e-15 57.1 0.0 2.7e-15 56.3 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.24 CBZ51519.1 - 1.9e-15 57.2 0.0 5.9e-15 55.6 0.0 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rep_fac_C PF08542.6 CBZ51519.1 - 7.4e-13 48.2 0.0 2e-12 46.9 0.0 1.8 2 0 0 2 2 1 1 Replication factor C C-terminal domain AAA_22 PF13401.1 CBZ51519.1 - 2.1e-09 37.5 0.0 4.7e-09 36.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.10 CBZ51519.1 - 3e-08 32.8 0.0 2.2e-07 29.9 0.0 2.1 1 1 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA_16 PF13191.1 CBZ51519.1 - 2.2e-06 27.8 0.1 1.1e-05 25.4 0.0 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.1 CBZ51519.1 - 2.2e-05 24.0 0.0 7.9e-05 22.3 0.0 2.0 1 0 0 1 1 1 1 Part of AAA domain AAA_11 PF13086.1 CBZ51519.1 - 4.4e-05 23.1 0.1 0.00014 21.5 0.1 1.8 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 CBZ51519.1 - 9.8e-05 21.5 0.0 0.00024 20.2 0.0 1.6 2 0 0 2 2 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_30 PF13604.1 CBZ51519.1 - 0.0001 21.9 0.0 0.00027 20.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 CBZ51519.1 - 0.00016 21.5 0.0 0.0035 17.2 0.0 2.3 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.8 CBZ51519.1 - 0.0017 17.3 0.0 0.0031 16.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) DUF2075 PF09848.4 CBZ51519.1 - 0.0024 16.9 0.0 0.0038 16.2 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) ResIII PF04851.10 CBZ51519.1 - 0.0034 17.2 0.0 0.03 14.1 0.0 2.1 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Arch_ATPase PF01637.13 CBZ51519.1 - 0.0038 16.9 0.0 0.006 16.3 0.0 1.3 1 0 0 1 1 1 1 Archaeal ATPase DEAD PF00270.24 CBZ51519.1 - 0.0092 15.4 0.1 0.099 12.1 0.1 2.4 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_25 PF13481.1 CBZ51519.1 - 0.0092 15.3 0.0 0.023 14.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 CBZ51519.1 - 0.01 15.5 0.1 0.051 13.2 0.1 2.0 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 CBZ51519.1 - 0.014 15.2 0.3 0.064 13.1 0.1 2.2 2 2 0 2 2 2 0 AAA domain Torsin PF06309.6 CBZ51519.1 - 0.015 15.1 0.0 0.032 14.1 0.0 1.5 1 0 0 1 1 1 0 Torsin AAA_10 PF12846.2 CBZ51519.1 - 0.022 14.1 0.0 6.1 6.1 0.0 2.3 2 0 0 2 2 2 0 AAA-like domain Zot PF05707.7 CBZ51519.1 - 0.035 13.5 0.0 0.074 12.5 0.0 1.5 1 0 0 1 1 1 0 Zonular occludens toxin (Zot) AAA_17 PF13207.1 CBZ51519.1 - 0.037 14.8 0.4 0.29 11.9 0.0 2.5 3 1 1 4 4 2 0 AAA domain TIP49 PF06068.8 CBZ51519.1 - 0.05 12.3 0.0 0.27 9.9 0.0 1.9 2 0 0 2 2 2 0 TIP49 C-terminus DNA_pol3_delta PF06144.8 CBZ51519.1 - 0.05 13.1 0.0 0.091 12.2 0.0 1.3 1 0 0 1 1 1 0 DNA polymerase III, delta subunit FtsK_SpoIIIE PF01580.13 CBZ51519.1 - 0.053 12.9 0.8 0.3 10.5 0.0 2.4 4 0 0 4 4 2 0 FtsK/SpoIIIE family MerR PF00376.18 CBZ51519.1 - 0.064 12.8 0.1 0.18 11.4 0.1 1.8 1 0 0 1 1 1 0 MerR family regulatory protein Mg_chelatase PF01078.16 CBZ51519.1 - 0.09 11.9 0.0 1.1 8.4 0.0 2.2 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 CBZ51519.1 - 0.091 12.3 0.0 1 8.9 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Viral_helicase1 PF01443.13 CBZ51519.1 - 0.1 12.0 0.0 0.24 10.8 0.0 1.6 2 0 0 2 2 1 0 Viral (Superfamily 1) RNA helicase AAA_28 PF13521.1 CBZ51519.1 - 0.14 12.1 0.2 0.34 10.8 0.1 1.8 1 1 0 1 1 1 0 AAA domain HNOBA PF07701.9 CBZ51520.1 - 1.1 8.4 3.2 7.8 5.6 0.6 2.3 2 0 0 2 2 2 0 Heme NO binding associated RNase_H2-Ydr279 PF09468.5 CBZ51520.1 - 1.3 8.2 11.3 0.63 9.1 0.9 2.3 2 0 0 2 2 2 0 Ydr279p protein family (RNase H2 complex component) DDHD PF02862.12 CBZ51520.1 - 7.5 6.2 22.4 0.92 9.2 1.5 3.3 3 0 0 3 3 3 0 DDHD domain IBR PF01485.16 CBZ51521.1 - 0.00016 21.5 2.9 0.00016 21.5 2.0 3.1 3 0 0 3 3 3 2 IBR domain zf-RING_2 PF13639.1 CBZ51521.1 - 0.0054 16.5 5.4 0.0054 16.5 3.8 3.6 3 0 0 3 3 3 1 Ring finger domain Clathrin_lg_ch PF01086.12 CBZ51522.1 - 1.1e-08 35.3 19.4 5.1e-08 33.1 13.2 2.3 1 1 0 1 1 1 1 Clathrin light chain Cupin_2 PF07883.6 CBZ51523.1 - 0.0017 17.8 0.0 0.0048 16.3 0.0 1.8 1 0 0 1 1 1 1 Cupin domain CENP-C_C PF11699.3 CBZ51523.1 - 0.03 14.2 0.0 0.062 13.2 0.0 1.4 1 0 0 1 1 1 0 Mif2/CENP-C like WD40 PF00400.27 CBZ51524.1 - 5.4e-15 54.6 10.7 0.0045 16.8 0.0 6.7 6 0 0 6 6 6 5 WD domain, G-beta repeat Peptidase_M20 PF01546.23 CBZ51524.1 - 7.1e-11 41.9 0.0 7.2e-09 35.4 0.0 3.3 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 GATase_6 PF13522.1 CBZ51524.1 - 0.0016 18.3 0.0 0.0087 16.0 0.0 2.1 2 0 0 2 2 2 1 Glutamine amidotransferase domain M20_dimer PF07687.9 CBZ51524.1 - 0.0057 16.3 0.0 0.14 11.9 0.0 2.6 2 1 0 2 2 2 1 Peptidase dimerisation domain ATP11 PF06644.6 CBZ51525.1 - 4.3e-31 108.3 3.6 5e-30 104.9 0.0 2.8 3 0 0 3 3 3 2 ATP11 protein Sec1 PF00995.18 CBZ51526.1 - 3e-41 141.7 0.0 3.6e-41 141.4 0.0 1.0 1 0 0 1 1 1 1 Sec1 family ATP11 PF06644.6 CBZ51527.1 - 2.1e-33 115.9 0.0 2.7e-33 115.6 0.0 1.0 1 0 0 1 1 1 1 ATP11 protein Sec1 PF00995.18 CBZ51528.1 - 8.7e-116 387.7 0.0 9.9e-116 387.6 0.0 1.0 1 0 0 1 1 1 1 Sec1 family VitK2_biosynth PF02621.9 CBZ51528.1 - 0.062 12.4 0.1 2.5 7.2 0.0 2.7 3 0 0 3 3 3 0 Menaquinone biosynthesis YGGT PF02325.12 CBZ51529.1 - 6.9e-13 48.3 1.4 1.1e-12 47.6 1.0 1.4 1 0 0 1 1 1 1 YGGT family CLP_protease PF00574.18 CBZ51530.1 - 2.6e-10 40.2 0.1 1.9e-08 34.2 0.0 2.1 1 1 0 1 1 1 1 Clp protease DUF3432 PF11914.3 CBZ51530.1 - 0.021 14.8 19.1 0.039 13.9 13.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3432) DUF305 PF03713.8 CBZ51530.1 - 0.033 14.0 0.1 0.047 13.5 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF305) DUF1049 PF06305.6 CBZ51531.1 - 0.5 9.8 2.6 1.7 8.1 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) SAG PF04092.8 CBZ51533.1 - 0.00042 20.6 0.0 0.00063 20.1 0.0 1.2 1 0 0 1 1 1 1 SRS domain Herpes_capsid PF06112.6 CBZ51534.1 - 0.24 11.4 9.5 0.041 13.9 2.2 2.3 2 0 0 2 2 2 0 Gammaherpesvirus capsid protein Dynamin_M PF01031.15 CBZ51535.1 - 5.2 5.7 0.0 8.7 5.0 0.0 1.2 1 0 0 1 1 1 0 Dynamin central region HHH PF00633.18 CBZ51536.1 - 0.0032 17.0 0.0 0.0095 15.6 0.0 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix motif RabGAP-TBC PF00566.13 CBZ51537.1 - 1.3e-22 80.3 3.2 1.9e-22 79.8 2.2 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain GMC_oxred_N PF00732.14 CBZ51538.1 - 2.7e-22 79.3 0.5 3.8e-12 45.9 0.0 3.2 3 0 0 3 3 3 2 GMC oxidoreductase GMC_oxred_C PF05199.8 CBZ51538.1 - 6.4e-18 65.4 0.0 6.8e-13 49.1 0.0 2.5 2 0 0 2 2 2 2 GMC oxidoreductase FAD_binding_2 PF00890.19 CBZ51538.1 - 0.0019 17.1 0.2 0.003 16.4 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 CBZ51538.1 - 0.0026 16.7 0.0 0.0053 15.7 0.0 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.9 CBZ51538.1 - 0.0046 15.4 0.2 0.009 14.5 0.0 1.5 2 0 0 2 2 2 1 HI0933-like protein Lycopene_cycl PF05834.7 CBZ51538.1 - 0.0077 15.1 0.0 0.011 14.6 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.9 CBZ51538.1 - 0.017 14.9 0.1 0.054 13.3 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 CBZ51538.1 - 0.039 13.9 0.1 0.091 12.8 0.1 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 CBZ51538.1 - 0.086 13.2 0.3 0.6 10.5 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ThiF PF00899.16 CBZ51538.1 - 0.1 12.4 0.5 21 4.9 0.2 3.1 3 0 0 3 3 3 0 ThiF family ApbA PF02558.11 CBZ51538.1 - 0.1 12.0 0.1 0.25 10.7 0.1 1.7 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA TrkA_N PF02254.13 CBZ51538.1 - 0.12 12.3 0.1 0.25 11.3 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain FAD_binding_3 PF01494.14 CBZ51538.1 - 0.12 11.3 0.1 0.2 10.7 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain Ribosomal_S19 PF00203.16 CBZ51539.1 - 2.2e-28 97.6 0.2 3.2e-28 97.1 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 LRR_6 PF13516.1 CBZ51540.1 - 3.8e-12 44.9 5.8 0.0034 17.2 0.2 5.5 6 0 0 6 6 6 4 Leucine Rich repeat LRR_4 PF12799.2 CBZ51540.1 - 5.6e-06 25.8 5.2 0.018 14.6 0.0 3.5 3 1 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 CBZ51540.1 - 1.8e-05 24.1 2.3 1.6 9.0 0.0 4.6 5 0 0 5 5 5 3 Leucine Rich Repeat LRR_8 PF13855.1 CBZ51540.1 - 8.2e-05 22.2 5.9 0.0085 15.8 1.5 3.1 2 1 2 4 4 4 3 Leucine rich repeat LRR_7 PF13504.1 CBZ51540.1 - 0.22 11.8 13.1 3.8 8.1 0.0 4.9 6 0 0 6 6 6 0 Leucine rich repeat FH2 PF02181.18 CBZ51541.1 - 7.3e-29 100.7 0.0 1.9e-28 99.4 0.0 1.6 2 0 0 2 2 2 1 Formin Homology 2 Domain zf-CCCH PF00642.19 CBZ51544.1 - 0.0041 16.7 8.4 0.0041 16.7 5.8 3.0 3 0 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 CBZ51544.1 - 0.18 11.8 8.4 0.57 10.2 3.0 2.8 2 1 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type LSM PF01423.17 CBZ51545.1 - 6.5e-20 70.4 0.1 7.7e-20 70.2 0.0 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 CBZ51545.1 - 0.0025 17.7 0.0 0.003 17.4 0.0 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain RAP PF08373.5 CBZ51546.1 - 4.9e-07 29.4 0.2 9e-07 28.5 0.1 1.4 1 0 0 1 1 1 1 RAP domain DUF1064 PF06356.6 CBZ51546.1 - 0.1 12.5 0.1 0.34 10.9 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1064) MmgE_PrpD PF03972.9 CBZ51548.1 - 2e-40 138.3 0.6 2.8e-40 137.8 0.4 1.1 1 0 0 1 1 1 1 MmgE/PrpD family zf-rbx1 PF12678.2 CBZ51549.1 - 7e-36 122.1 11.8 8.8e-36 121.8 8.2 1.1 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 CBZ51549.1 - 4.4e-17 61.6 9.3 5.7e-17 61.3 6.5 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.1 CBZ51549.1 - 1.6e-07 30.9 11.7 9.8e-07 28.5 8.1 2.0 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 CBZ51549.1 - 0.0013 18.3 11.2 0.013 15.1 7.8 2.2 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CBZ51549.1 - 0.0019 18.1 3.1 0.0019 18.1 2.1 2.3 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CBZ51549.1 - 0.0038 16.8 9.4 0.3 10.8 6.7 2.2 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBZ51549.1 - 0.24 11.1 10.0 1 9.1 6.9 2.0 1 1 0 1 1 1 0 zinc-RING finger domain FANCL_C PF11793.3 CBZ51549.1 - 0.26 11.2 8.0 2.1 8.3 5.8 2.0 1 1 1 2 2 2 0 FANCL C-terminal domain zf-HC5HC2H_2 PF13832.1 CBZ51549.1 - 0.96 9.4 8.7 2.1 8.3 6.0 1.6 1 1 0 1 1 1 0 PHD-zinc-finger like domain zf-RING_UBOX PF13445.1 CBZ51549.1 - 1 9.1 6.9 22 4.8 4.8 2.2 1 1 0 1 1 1 0 RING-type zinc-finger zf-HC5HC2H PF13771.1 CBZ51549.1 - 2.7 8.2 10.5 99 3.1 7.3 2.2 1 1 0 1 1 1 0 PHD-like zinc-binding domain WD40 PF00400.27 CBZ51551.1 - 8.9e-19 66.6 19.1 2.7e-08 33.3 0.0 6.3 7 0 0 7 7 7 4 WD domain, G-beta repeat Cren7 PF11520.3 CBZ51552.1 - 0.019 14.5 0.0 0.04 13.5 0.0 1.5 1 0 0 1 1 1 0 Chromatin protein Cren7 LANC_like PF05147.8 CBZ51553.1 - 9.5e-64 215.1 0.0 1.1e-63 214.9 0.0 1.1 1 0 0 1 1 1 1 Lanthionine synthetase C-like protein Methyltransf_18 PF12847.2 CBZ51554.1 - 5.4e-16 59.1 0.1 3.8e-11 43.5 0.0 2.9 3 0 0 3 3 3 2 Methyltransferase domain Methyltransf_31 PF13847.1 CBZ51554.1 - 1.8e-15 56.8 0.0 9.5e-11 41.5 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_26 PF13659.1 CBZ51554.1 - 4e-09 36.5 0.0 0.00068 19.6 0.0 2.8 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.7 CBZ51554.1 - 1.6e-08 34.9 0.2 0.00013 22.3 0.0 3.7 2 2 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.7 CBZ51554.1 - 3e-08 34.0 0.0 5.4e-05 23.5 0.0 3.7 3 1 0 3 3 3 1 Methyltransferase domain Methyltransf_25 PF13649.1 CBZ51554.1 - 2.4e-07 31.0 0.0 0.0008 19.7 0.0 3.3 3 1 0 3 3 3 2 Methyltransferase domain Methyltransf_23 PF13489.1 CBZ51554.1 - 4.3e-07 29.7 0.0 0.00038 20.2 0.0 3.3 2 2 0 2 2 2 1 Methyltransferase domain Spermine_synth PF01564.12 CBZ51554.1 - 3.9e-06 25.9 0.0 0.0055 15.6 0.0 2.4 2 1 0 2 2 2 2 Spermine/spermidine synthase Methyltransf_24 PF13578.1 CBZ51554.1 - 0.00019 22.2 0.0 0.0065 17.2 0.0 3.1 3 0 0 3 3 3 1 Methyltransferase domain Ubie_methyltran PF01209.13 CBZ51554.1 - 0.0044 16.1 0.0 0.19 10.7 0.0 2.7 3 0 0 3 3 3 1 ubiE/COQ5 methyltransferase family Calici_PP_N PF08405.6 CBZ51554.1 - 0.0086 14.9 0.0 0.014 14.2 0.0 1.2 1 0 0 1 1 1 1 Viral polyprotein N-terminal TPMT PF05724.6 CBZ51554.1 - 0.051 13.0 0.1 7.2 5.9 0.0 2.4 2 0 0 2 2 2 0 Thiopurine S-methyltransferase (TPMT) Herpes_UL52 PF03121.10 CBZ51556.1 - 5e-13 48.5 0.1 1.1e-12 47.4 0.1 1.5 1 0 0 1 1 1 1 Herpesviridae UL52/UL70 DNA primase rRNA_proc-arch PF13234.1 CBZ51558.1 - 4.1e-68 229.4 0.0 7.6e-68 228.5 0.0 1.5 1 0 0 1 1 1 1 rRNA-processing arch domain DSHCT PF08148.7 CBZ51558.1 - 1.9e-51 173.8 3.7 2.2e-51 173.6 0.6 2.6 2 1 0 2 2 2 1 DSHCT (NUC185) domain DEAD PF00270.24 CBZ51558.1 - 5e-22 78.1 0.1 2.4e-21 75.9 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CBZ51558.1 - 2.9e-07 30.2 0.4 1.5e-06 27.9 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 CBZ51558.1 - 0.011 15.5 0.0 0.036 13.8 0.0 2.0 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Mob_synth_C PF06463.8 CBZ51559.1 - 5.2e-30 103.7 0.1 4.8e-19 68.3 0.0 3.2 2 1 1 3 3 3 3 Molybdenum Cofactor Synthesis C Radical_SAM PF04055.16 CBZ51559.1 - 2.4e-15 57.1 0.0 4.8e-15 56.1 0.0 1.5 1 0 0 1 1 1 1 Radical SAM superfamily ALMS_motif PF15309.1 CBZ51559.1 - 0.022 14.5 0.0 0.041 13.7 0.0 1.3 1 0 0 1 1 1 0 ALMS motif CRAL_TRIO PF00650.15 CBZ51560.1 - 8.7e-19 67.5 0.0 1.3e-18 66.9 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain ACBP PF00887.14 CBZ51560.1 - 7.1e-06 25.5 0.0 1.5e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 Acyl CoA binding protein CRAL_TRIO_2 PF13716.1 CBZ51560.1 - 0.043 13.7 0.0 0.071 13.0 0.0 1.3 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain DUF3181 PF11378.3 CBZ51560.1 - 0.047 13.7 0.7 0.12 12.3 0.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3181) EF-hand_1 PF00036.27 CBZ51561.1 - 4.1e-27 91.3 7.2 2.8e-07 29.3 0.2 4.6 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 CBZ51561.1 - 1.5e-23 82.6 4.8 8.1e-12 45.0 0.6 2.7 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.1 CBZ51561.1 - 4.1e-21 73.3 5.5 2e-06 26.8 0.2 4.6 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.1 CBZ51561.1 - 5.3e-20 69.4 6.5 0.001 18.7 0.0 4.4 3 1 1 4 4 4 4 EF-hand domain EF-hand_8 PF13833.1 CBZ51561.1 - 6.3e-15 54.5 6.3 4.9e-06 26.0 1.5 4.0 3 1 1 4 4 4 2 EF-hand domain pair SPARC_Ca_bdg PF10591.4 CBZ51561.1 - 9.5e-09 35.2 0.1 0.0011 18.9 0.0 2.2 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 CBZ51561.1 - 2.3e-05 24.0 4.3 0.073 12.8 0.4 3.3 1 1 3 4 4 4 2 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.1 CBZ51561.1 - 0.00098 18.9 0.1 0.066 13.1 0.0 3.0 3 0 0 3 3 3 1 EF-hand domain Caleosin PF05042.8 CBZ51561.1 - 0.06 12.9 0.1 2.6 7.5 0.0 2.6 1 1 2 3 3 3 0 Caleosin related protein VCBS PF13517.1 CBZ51561.1 - 0.5 10.7 3.6 0.74 10.2 0.5 2.5 2 1 1 3 3 3 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Fe-S_biosyn PF01521.15 CBZ51562.1 - 1.3e-10 41.1 0.0 2.7e-09 36.9 0.0 2.4 2 0 0 2 2 2 1 Iron-sulphur cluster biosynthesis MIP-T3 PF10243.4 CBZ51563.1 - 0.74 8.2 24.7 1.3 7.3 17.1 1.3 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 UFC1 PF08694.6 CBZ51564.1 - 7.6e-68 227.0 0.0 9e-68 226.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-fold modifier-conjugating enzyme 1 UQ_con PF00179.21 CBZ51564.1 - 0.0038 16.6 0.2 0.016 14.6 0.1 1.9 1 1 0 1 1 1 1 Ubiquitin-conjugating enzyme Glyco_hydro_61 PF03443.9 CBZ51564.1 - 0.035 13.9 0.0 0.045 13.5 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 61 RPA_interact_N PF14766.1 CBZ51564.1 - 0.091 12.2 0.6 0.18 11.2 0.0 1.8 2 0 0 2 2 2 0 Replication protein A interacting N-terminal Prok-E2_B PF14461.1 CBZ51564.1 - 0.11 12.2 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 Prokaryotic E2 family B Choline_transpo PF04515.7 CBZ51565.1 - 3.3e-42 144.4 44.0 1.9e-26 92.5 9.4 4.0 3 2 1 4 4 4 3 Plasma-membrane choline transporter DUF342 PF03961.8 CBZ51567.1 - 0.21 9.9 1.9 0.26 9.6 1.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Coagulase PF08764.5 CBZ51567.1 - 0.43 10.4 3.9 1.1 9.1 1.3 1.9 2 0 0 2 2 2 0 Staphylococcus aureus coagulase UCH PF00443.24 CBZ51568.1 - 4.4e-33 114.5 0.0 5.5e-33 114.2 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CBZ51568.1 - 1.6e-12 47.4 0.0 8e-12 45.2 0.0 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UBA PF00627.26 CBZ51568.1 - 1.2e-08 34.5 1.9 1.8e-05 24.3 0.0 3.0 3 0 0 3 3 3 2 UBA/TS-N domain zf-UBP PF02148.14 CBZ51569.1 - 9.6e-14 51.2 0.0 3.4e-13 49.4 0.0 2.0 1 1 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein Myb_DNA-binding PF00249.26 CBZ51571.1 - 0.14 12.2 0.0 0.33 11.0 0.0 1.6 1 0 0 1 1 1 0 Myb-like DNA-binding domain UPF0223 PF05256.7 CBZ51571.1 - 0.21 11.7 1.7 12 6.0 0.1 2.5 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0223) RCC1 PF00415.13 CBZ51572.1 - 2.8e-40 136.3 17.5 4e-09 36.5 0.5 8.2 7 2 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 CBZ51572.1 - 4.7e-17 61.1 41.7 2.2e-06 27.1 0.7 6.8 7 0 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat zf-RanBP PF00641.13 CBZ51572.1 - 1.7e-05 23.7 3.4 3.4e-05 22.8 2.3 1.5 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others DUF1700 PF08006.6 CBZ51573.1 - 4.4 6.5 5.3 7 5.9 3.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) DUF919 PF06034.6 CBZ51574.1 - 0.025 14.2 0.1 0.068 12.8 0.0 1.7 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF919) RNase_PH PF01138.16 CBZ51575.1 - 3.6e-13 49.9 0.5 2.7e-12 47.1 0.1 2.4 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 CBZ51575.1 - 0.0023 17.8 0.0 0.0055 16.6 0.0 1.6 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 CHCH PF06747.8 CBZ51576.1 - 5.2e-06 26.2 6.1 8.1e-06 25.6 4.2 1.3 1 0 0 1 1 1 1 CHCH domain Cmc1 PF08583.5 CBZ51576.1 - 0.01 15.5 2.0 0.18 11.6 0.1 2.2 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like IL13 PF03487.8 CBZ51576.1 - 2.9 7.6 5.6 4 7.2 0.1 2.8 2 0 0 2 2 2 0 Interleukin-13 DUF1211 PF06736.6 CBZ51577.1 - 0.03 14.4 0.3 0.03 14.4 0.2 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1211) Nol1_Nop2_Fmu PF01189.12 CBZ51578.1 - 3.2e-15 56.2 0.0 3.9e-15 55.9 0.0 1.1 1 0 0 1 1 1 1 NOL1/NOP2/sun family Ubie_methyltran PF01209.13 CBZ51578.1 - 5.8e-07 28.8 0.0 8.5e-07 28.3 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.1 CBZ51578.1 - 1.6e-06 27.7 0.0 2.9e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 CBZ51578.1 - 0.0011 18.5 0.0 0.0017 17.9 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_25 PF13649.1 CBZ51578.1 - 0.0023 18.2 0.0 0.0042 17.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain GCD14 PF08704.5 CBZ51578.1 - 0.006 16.1 0.0 0.0086 15.6 0.0 1.1 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit MTS PF05175.9 CBZ51578.1 - 0.033 13.5 0.0 0.053 12.8 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_18 PF12847.2 CBZ51578.1 - 0.097 13.2 0.0 0.19 12.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain DUF2638 PF10937.3 CBZ51579.1 - 0.57 11.2 2.9 3.4 8.7 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2638) PK PF00224.16 CBZ51580.1 - 0.51 8.9 0.0 0.75 8.3 0.0 1.1 1 0 0 1 1 1 0 Pyruvate kinase, barrel domain PapJ PF14855.1 CBZ51581.1 - 0.13 11.7 0.1 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 Pilus-assembly fibrillin subunit, chaperone Sulfate_transp PF00916.15 CBZ51582.1 - 1.5e-15 56.9 21.5 5.2e-10 38.8 2.8 3.2 3 0 0 3 3 3 2 Sulfate transporter family Proteasome PF00227.21 CBZ51584.1 - 2.7e-61 206.2 0.0 4.4e-61 205.4 0.0 1.3 2 0 0 2 2 2 1 Proteasome subunit Proteasome_A_N PF10584.4 CBZ51584.1 - 9e-11 40.8 0.9 1.8e-10 39.8 0.0 1.9 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature RecA PF00154.16 CBZ51584.1 - 0.093 11.7 0.0 0.15 11.1 0.0 1.3 1 0 0 1 1 1 0 recA bacterial DNA recombination protein DNA_pol_phi PF04931.8 CBZ51585.1 - 0.00081 17.3 19.6 0.00081 17.3 13.6 3.6 3 1 0 3 3 3 3 DNA polymerase phi Kinesin PF00225.18 CBZ51587.1 - 1.7e-82 276.7 0.0 2.3e-82 276.3 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain Dynein_heavy PF03028.10 CBZ51588.1 - 9.5e-107 357.7 0.0 4.4e-60 203.5 0.0 4.0 3 1 1 4 4 4 4 Dynein heavy chain and region D6 of dynein motor DHC_N2 PF08393.8 CBZ51589.1 - 2.2e-114 382.1 0.1 2.2e-114 382.1 0.0 2.8 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 2 AAA_6 PF12774.2 CBZ51589.1 - 2.1e-79 266.3 0.1 4.7e-78 261.8 0.0 2.7 2 1 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region D1 MT PF12777.2 CBZ51589.1 - 1.7e-43 148.7 7.4 1.7e-43 148.7 5.2 1.8 2 0 0 2 2 2 1 Microtubule-binding stalk of dynein motor AAA_9 PF12781.2 CBZ51589.1 - 3.4e-40 137.3 0.1 9.6e-40 135.8 0.0 1.8 2 0 0 2 2 2 1 ATP-binding dynein motor region D5 AAA_8 PF12780.2 CBZ51589.1 - 5.5e-38 130.4 0.1 1.4e-21 76.6 0.0 3.4 3 0 0 3 3 3 2 P-loop containing dynein motor region D4 AAA_7 PF12775.2 CBZ51589.1 - 4.1e-37 127.7 0.0 1.6e-36 125.8 0.0 1.9 2 0 0 2 2 2 1 P-loop containing dynein motor region D3 AAA_5 PF07728.9 CBZ51589.1 - 1.4e-12 47.4 0.0 0.0075 16.0 0.0 5.6 5 1 0 5 5 5 3 AAA domain (dynein-related subfamily) AAA PF00004.24 CBZ51589.1 - 3.4e-07 30.5 0.1 0.086 13.0 0.0 4.1 4 0 0 4 4 3 2 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 CBZ51589.1 - 2e-06 28.6 0.2 0.013 16.2 0.0 4.3 4 0 0 4 4 3 1 AAA domain AAA_18 PF13238.1 CBZ51589.1 - 3.8e-06 27.2 0.5 0.044 14.1 0.0 3.9 4 0 0 4 4 4 2 AAA domain T2SE PF00437.15 CBZ51589.1 - 5.4e-06 25.5 0.1 4.6e-05 22.4 0.0 2.6 3 0 0 3 3 3 1 Type II/IV secretion system protein AAA_28 PF13521.1 CBZ51589.1 - 3.2e-05 23.9 0.1 0.69 9.8 0.0 4.4 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.1 CBZ51589.1 - 0.00021 21.4 1.7 1.6 8.8 0.0 4.4 4 0 0 4 4 3 2 AAA domain Zeta_toxin PF06414.7 CBZ51589.1 - 0.0033 16.5 0.0 3.6 6.6 0.0 3.1 2 0 0 2 2 2 2 Zeta toxin AAA_33 PF13671.1 CBZ51589.1 - 0.0064 16.3 1.6 10 5.9 0.0 4.9 5 0 0 5 5 5 0 AAA domain Baculo_PEP_C PF04513.7 CBZ51589.1 - 0.018 14.8 0.2 0.018 14.8 0.1 6.8 7 1 0 7 7 7 0 Baculovirus polyhedron envelope protein, PEP, C terminus AAA_29 PF13555.1 CBZ51589.1 - 0.034 13.6 4.1 18 4.9 0.1 3.9 4 0 0 4 4 4 0 P-loop containing region of AAA domain RNA_helicase PF00910.17 CBZ51589.1 - 0.073 13.2 0.0 49 4.1 0.0 3.6 3 0 0 3 3 3 0 RNA helicase MobB PF03205.9 CBZ51589.1 - 0.45 10.2 1.1 11 5.6 0.0 3.2 3 0 0 3 3 2 0 Molybdopterin guanine dinucleotide synthesis protein B Sec8_exocyst PF04048.9 CBZ51589.1 - 5.1 6.7 12.1 0.059 12.9 0.2 3.6 3 0 0 3 3 3 0 Sec8 exocyst complex component specific domain SWIRM PF04433.12 CBZ51590.1 - 8e-24 83.5 0.0 1.6e-23 82.5 0.0 1.6 1 0 0 1 1 1 1 SWIRM domain Myb_DNA-binding PF00249.26 CBZ51590.1 - 7.5e-10 38.7 0.0 1.7e-09 37.5 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 CBZ51590.1 - 3.6e-08 33.3 0.0 1.2e-07 31.7 0.0 1.9 2 0 0 2 2 2 1 Myb-like DNA-binding domain DUF4205 PF13898.1 CBZ51592.1 - 1.2e-48 165.6 0.0 1.5e-40 139.0 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF4205) EF-hand_7 PF13499.1 CBZ51592.1 - 0.015 15.4 0.0 0.064 13.4 0.0 2.1 1 0 0 1 1 1 0 EF-hand domain pair DUF3115 PF11312.3 CBZ51592.1 - 0.13 11.1 0.1 0.2 10.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3115) UIM PF02809.15 CBZ51592.1 - 1.6 8.5 14.9 0.46 10.1 0.5 3.6 3 0 0 3 3 3 0 Ubiquitin interaction motif Pinin_SDK_memA PF04696.8 CBZ51593.1 - 3.4e-05 23.4 10.5 3.4e-05 23.4 7.3 2.4 2 0 0 2 2 2 1 pinin/SDK/memA/ protein conserved region Pedibin PF08182.6 CBZ51593.1 - 3 7.4 6.8 0.57 9.7 0.4 2.8 3 0 0 3 3 3 0 Pedibin/Hym-346 family RNA_polI_A34 PF08208.6 CBZ51593.1 - 3.6 7.2 17.2 0.21 11.2 5.6 2.2 2 0 0 2 2 2 0 DNA-directed RNA polymerase I subunit RPA34.5 Cu_amine_oxid PF01179.15 CBZ51594.1 - 1.8e-78 264.1 0.9 2.9e-78 263.4 0.6 1.3 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain MAM PF00629.18 CBZ51594.1 - 8.6e-30 103.6 0.0 1.5e-29 102.8 0.0 1.4 1 0 0 1 1 1 1 MAM domain MCPsignal PF00015.16 CBZ51596.1 - 0.039 13.4 1.3 0.07 12.6 0.8 1.5 1 1 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Spore_III_AB PF09548.5 CBZ51596.1 - 0.18 11.5 3.3 0.4 10.4 1.1 2.0 2 0 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) MA3 PF02847.12 CBZ51597.1 - 4.5e-44 148.7 8.4 4.5e-16 58.5 0.1 3.2 3 0 0 3 3 3 3 MA3 domain EGF_3 PF12947.2 CBZ51598.1 - 0.0042 17.0 104.9 0.037 13.9 6.4 10.8 10 0 0 10 10 10 7 EGF domain EGF_MSP1_1 PF12946.2 CBZ51598.1 - 0.013 15.3 3.1 0.013 15.3 2.2 8.3 7 1 0 7 7 7 0 MSP1 EGF domain 1 cEGF PF12662.2 CBZ51598.1 - 0.015 14.8 0.9 0.015 14.8 0.6 10.0 10 0 0 10 10 10 0 Complement Clr-like EGF-like HemX PF04375.9 CBZ51598.1 - 0.2 10.1 0.1 0.28 9.7 0.0 1.1 1 0 0 1 1 1 0 HemX FXa_inhibition PF14670.1 CBZ51598.1 - 3.1 7.9 131.9 0.029 14.5 4.9 10.9 7 2 3 10 10 10 0 Coagulation Factor Xa inhibitory site SRP19 PF01922.12 CBZ51599.1 - 6.7e-21 74.6 0.0 5.9e-13 49.2 0.0 2.1 2 0 0 2 2 2 2 SRP19 protein HSP20 PF00011.16 CBZ51600.1 - 3.4e-26 91.0 0.3 4.9e-26 90.5 0.2 1.2 1 0 0 1 1 1 1 Hsp20/alpha crystallin family zf-C2H2_4 PF13894.1 CBZ51601.1 - 1.3e-05 25.1 2.1 0.073 13.4 0.1 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 CBZ51601.1 - 6e-05 23.0 3.1 0.0017 18.4 0.6 2.3 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.21 CBZ51601.1 - 0.0024 18.0 2.0 0.33 11.4 0.2 2.3 2 0 0 2 2 2 2 Zinc finger, C2H2 type LIM PF00412.17 CBZ51601.1 - 0.025 14.6 2.1 0.042 13.9 1.5 1.3 1 0 0 1 1 1 0 LIM domain zf-Di19 PF05605.7 CBZ51601.1 - 0.13 12.4 3.8 0.89 9.7 2.7 2.0 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_6 PF13912.1 CBZ51601.1 - 0.21 11.5 0.1 0.21 11.5 0.0 2.1 1 1 1 2 2 2 0 C2H2-type zinc finger PyrI_C PF02748.10 CBZ51601.1 - 3 7.3 4.5 1.4 8.4 0.4 2.1 1 1 1 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain Kin17_mid PF10357.4 CBZ51602.1 - 4.9e-42 142.5 3.0 9.6e-42 141.6 2.1 1.5 1 0 0 1 1 1 1 Domain of Kin17 curved DNA-binding protein zf-met PF12874.2 CBZ51602.1 - 0.012 15.7 3.2 0.029 14.5 2.2 1.6 1 0 0 1 1 1 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 CBZ51602.1 - 0.06 13.5 4.1 0.14 12.2 2.8 1.7 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding Kinesin PF00225.18 CBZ51605.1 - 2.3e-95 319.1 0.0 2.9e-95 318.8 0.0 1.1 1 0 0 1 1 1 1 Kinesin motor domain MMR_HSR1 PF01926.18 CBZ51607.1 - 5.5e-11 42.4 0.1 2.6e-09 37.0 0.0 2.2 1 1 1 2 2 2 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 CBZ51607.1 - 1.1e-05 25.3 0.0 1.6e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 Dynamin family FeoB_N PF02421.13 CBZ51607.1 - 0.00041 19.6 0.5 0.00078 18.7 0.0 1.6 2 0 0 2 2 2 1 Ferrous iron transport protein B Miro PF08477.8 CBZ51607.1 - 0.011 16.2 0.0 0.046 14.2 0.0 2.0 1 1 0 1 1 1 0 Miro-like protein AAA_10 PF12846.2 CBZ51607.1 - 0.015 14.7 0.1 0.27 10.6 0.0 2.1 2 0 0 2 2 2 0 AAA-like domain ABC_tran PF00005.22 CBZ51607.1 - 0.021 15.1 0.0 0.037 14.3 0.0 1.4 1 0 0 1 1 1 0 ABC transporter GTP_EFTU PF00009.22 CBZ51607.1 - 0.025 14.0 0.1 2.8 7.3 0.0 2.2 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain DUF258 PF03193.11 CBZ51607.1 - 0.071 12.2 0.0 0.099 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_17 PF13207.1 CBZ51607.1 - 0.095 13.5 0.0 0.18 12.6 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.1 CBZ51607.1 - 0.11 12.0 0.0 0.27 10.7 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Redoxin PF08534.5 CBZ51608.1 - 4e-27 94.5 0.0 5.6e-27 94.0 0.0 1.2 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 CBZ51608.1 - 1.7e-11 43.8 0.0 2.3e-11 43.4 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family S1 PF00575.18 CBZ51609.1 - 9.5e-24 83.2 0.5 2.1e-12 46.9 0.0 3.4 3 0 0 3 3 3 3 S1 RNA binding domain DUF3131 PF11329.3 CBZ51609.1 - 0.16 10.6 0.0 0.26 9.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3131) DUF605 PF04652.11 CBZ51609.1 - 3 7.1 8.4 7 5.9 5.8 1.5 1 0 0 1 1 1 0 Vta1 like Abhydrolase_6 PF12697.2 CBZ51612.1 - 2.1e-10 40.8 1.5 2.1e-09 37.6 0.1 3.1 3 1 0 3 3 3 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CBZ51612.1 - 2.8e-06 27.1 0.0 1.3e-05 24.9 0.0 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 CBZ51612.1 - 4.9e-05 23.0 0.2 0.002 17.9 0.0 2.4 2 0 0 2 2 2 1 Putative lysophospholipase Abhydrolase_3 PF07859.8 CBZ51612.1 - 0.0088 15.6 0.0 0.77 9.2 0.0 2.8 2 1 0 2 2 2 1 alpha/beta hydrolase fold DUF3530 PF12048.3 CBZ51612.1 - 0.089 11.7 5.2 0.37 9.7 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3530) LSM PF01423.17 CBZ51613.1 - 4.6e-17 61.3 0.0 5.4e-17 61.1 0.0 1.1 1 0 0 1 1 1 1 LSM domain RNase_PH PF01138.16 CBZ51614.1 - 1.8e-12 47.7 0.0 4.6e-12 46.4 0.0 1.7 1 1 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 CBZ51614.1 - 0.0028 17.5 0.0 0.0054 16.6 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Gag_p17 PF00540.13 CBZ51615.1 - 0.14 11.9 0.0 0.21 11.3 0.0 1.2 1 0 0 1 1 1 0 gag gene protein p17 (matrix protein) EmrE PF13536.1 CBZ51618.1 - 1.9e-08 34.4 2.0 1.1e-07 32.0 0.9 2.3 2 0 0 2 2 2 1 Multidrug resistance efflux transporter EamA PF00892.15 CBZ51618.1 - 0.071 13.1 5.3 0.029 14.3 1.3 2.1 2 0 0 2 2 2 0 EamA-like transporter family DUF360 PF04020.8 CBZ51618.1 - 2 8.7 7.6 1.3 9.4 0.2 2.7 3 0 0 3 3 3 0 Membrane protein of unknown function ABA_GPCR PF12430.3 CBZ51619.1 - 2.5e-29 101.8 4.9 2.5e-29 101.8 3.4 1.7 2 0 0 2 2 2 1 Abscisic acid G-protein coupled receptor DUF3735 PF12537.3 CBZ51619.1 - 1.1e-19 70.2 0.1 2.2e-19 69.2 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3735) DUF1700 PF08006.6 CBZ51619.1 - 0.033 13.4 0.5 0.033 13.4 0.4 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1700) TM_helix PF05552.7 CBZ51619.1 - 1.6 8.4 5.4 2 8.1 0.8 2.4 2 0 0 2 2 2 0 Conserved TM helix Pkinase PF00069.20 CBZ51620.1 - 9e-66 221.6 0.0 1.2e-65 221.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ51620.1 - 6e-36 123.8 0.0 8.8e-36 123.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBZ51620.1 - 4.6e-05 22.5 0.0 6.7e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like YrbL-PhoP_reg PF10707.4 CBZ51620.1 - 0.03 13.6 0.0 0.066 12.5 0.0 1.5 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL APH PF01636.18 CBZ51620.1 - 0.077 12.7 0.0 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.9 CBZ51620.1 - 0.11 11.5 0.0 0.23 10.5 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF2534 PF10749.4 CBZ51621.1 - 0.71 9.8 3.6 11 5.9 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2534) TUDOR PF00567.19 CBZ51622.1 - 6.1e-08 32.5 1.2 2.9e-06 27.1 0.0 2.7 2 1 0 2 2 2 2 Tudor domain SMN PF06003.7 CBZ51622.1 - 0.00034 19.8 0.6 0.00034 19.8 0.4 2.4 1 1 0 2 2 2 1 Survival motor neuron protein (SMN) DUF4475 PF14753.1 CBZ51623.1 - 3.8e-42 144.0 9.2 1.1e-32 113.1 3.5 2.0 1 1 1 2 2 2 2 Domain of unknown function (DUF4475) EGF_3 PF12947.2 CBZ51623.1 - 1.6 8.7 14.8 1.6 8.7 0.2 3.8 3 1 0 3 3 3 0 EGF domain GTP_EFTU PF00009.22 CBZ51624.1 - 3.2e-56 189.7 0.0 5.2e-56 189.0 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 CBZ51624.1 - 6.8e-36 122.4 0.3 2.8e-35 120.4 0.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 CBZ51624.1 - 4.3e-15 55.5 0.3 1.4e-14 53.9 0.2 2.0 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 CBZ51624.1 - 0.00018 21.4 0.0 0.00057 19.8 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.1 CBZ51624.1 - 0.00079 19.0 0.2 0.0026 17.3 0.1 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 4 FlpD PF02662.11 CBZ51624.1 - 0.022 14.4 0.1 0.068 12.8 0.0 1.8 2 0 0 2 2 2 0 Methyl-viologen-reducing hydrogenase, delta subunit FAST_1 PF06743.10 CBZ51625.1 - 7.6e-05 22.3 1.9 0.14 11.8 0.0 4.9 4 0 0 4 4 4 2 FAST kinase-like protein, subdomain 1 SAPS PF04499.10 CBZ51626.1 - 1.1 7.7 0.8 3 6.3 0.6 1.6 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein SARS_3b PF12383.3 CBZ51626.1 - 4.6 7.1 0.5 9.6 6.1 0.3 1.4 1 0 0 1 1 1 0 Severe acute respiratory syndrome coronavirus 3b protein RNA_pol_Rpb1_1 PF04997.7 CBZ51626.1 - 7.6 5.6 0.0 15 4.6 0.0 1.4 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 1 DUF1402 PF07182.6 CBZ51626.1 - 8.1 5.2 0.0 14 4.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1402) TPR_12 PF13424.1 CBZ51627.1 - 2.5e-17 62.5 5.0 0.00035 20.4 0.4 4.4 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_2 PF07719.12 CBZ51627.1 - 1.2e-13 49.8 9.0 0.00023 20.8 0.1 4.4 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.1 CBZ51627.1 - 2.7e-11 43.0 6.6 0.008 16.7 0.3 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.23 CBZ51627.1 - 5.1e-11 41.6 9.1 1.2e-05 24.7 1.0 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.1 CBZ51627.1 - 2e-10 40.1 7.5 0.00068 19.2 2.3 4.1 3 1 1 4 4 4 2 TPR repeat TPR_8 PF13181.1 CBZ51627.1 - 2e-09 36.5 6.3 0.027 14.2 0.6 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.1 CBZ51627.1 - 3e-08 32.8 3.7 0.0081 15.8 0.1 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.1 CBZ51627.1 - 5.1e-07 30.1 8.5 0.13 13.0 0.2 4.2 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_10 PF13374.1 CBZ51627.1 - 9.2e-06 25.4 13.5 0.28 11.1 0.2 4.7 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_6 PF13174.1 CBZ51627.1 - 2e-05 24.7 10.0 0.17 12.4 0.7 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_4 PF07721.9 CBZ51627.1 - 0.00032 20.8 11.1 0.0045 17.2 0.0 4.4 5 0 0 5 5 3 2 Tetratricopeptide repeat TPR_17 PF13431.1 CBZ51627.1 - 0.00053 19.9 0.7 7 7.1 0.0 4.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 CBZ51627.1 - 0.012 15.8 10.9 0.12 12.7 0.4 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat Apc3 PF12895.2 CBZ51627.1 - 0.022 14.8 2.3 5.7 7.1 0.0 3.3 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 SNAP PF14938.1 CBZ51627.1 - 0.025 13.7 1.7 0.058 12.5 1.2 1.6 1 0 0 1 1 1 0 Soluble NSF attachment protein, SNAP RPN7 PF10602.4 CBZ51627.1 - 0.057 12.8 0.1 0.35 10.2 0.1 2.2 2 0 0 2 2 2 0 26S proteasome subunit RPN7 DUF3366 PF11846.3 CBZ51627.1 - 0.078 12.8 1.0 8.5 6.2 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF3366) TPR_9 PF13371.1 CBZ51627.1 - 0.093 12.5 9.8 6.2 6.7 1.3 3.9 4 1 0 4 4 4 0 Tetratricopeptide repeat SARS_X4 PF08779.5 CBZ51628.1 - 1.3 9.1 6.7 5.2 7.3 0.1 4.4 2 1 2 4 4 4 0 SARS coronavirus X4 like cEGF PF12662.2 CBZ51628.1 - 3.8 7.2 41.2 6.4 6.5 0.2 10.3 10 0 0 10 10 10 0 Complement Clr-like EGF-like EB PF01683.13 CBZ51628.1 - 9.3 6.4 49.4 14 5.8 0.7 9.6 5 4 1 6 6 6 0 EB module Kelch_4 PF13418.1 CBZ51629.1 - 3.2e-53 177.2 7.6 2.6e-09 36.7 0.1 6.5 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_3 PF13415.1 CBZ51629.1 - 6.9e-50 166.1 17.6 2.6e-10 40.1 0.0 7.6 7 0 0 7 7 7 6 Galactose oxidase, central domain Kelch_5 PF13854.1 CBZ51629.1 - 4.3e-45 151.0 0.0 4.1e-09 36.2 0.0 6.6 6 0 0 6 6 6 6 Kelch motif Kelch_2 PF07646.10 CBZ51629.1 - 4.1e-44 146.7 0.7 4.2e-08 32.6 0.0 6.5 6 0 0 6 6 6 6 Kelch motif Kelch_1 PF01344.20 CBZ51629.1 - 3.4e-39 132.1 0.0 1.1e-06 28.0 0.0 6.4 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.1 CBZ51629.1 - 6e-37 124.3 0.5 5.9e-06 26.2 0.0 6.5 5 1 1 6 6 6 6 Kelch motif BTB PF00651.26 CBZ51629.1 - 2e-21 76.0 0.2 2.7e-20 72.4 0.0 2.2 1 1 1 2 2 2 1 BTB/POZ domain RAG2 PF03089.9 CBZ51629.1 - 0.012 14.3 0.0 1.9 7.1 0.0 2.9 3 0 0 3 3 3 0 Recombination activating protein 2 BACK PF07707.10 CBZ51629.1 - 0.016 15.0 0.2 0.1 12.4 0.0 2.3 3 0 0 3 3 3 0 BTB And C-terminal Kelch Epimerase PF01370.16 CBZ51631.1 - 2.8e-20 72.7 0.0 3.4e-20 72.4 0.0 1.0 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Metallophos PF00149.23 CBZ51632.1 - 1.2e-39 135.8 0.1 1.5e-39 135.4 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase NYD-SP12_N PF15015.1 CBZ51632.1 - 0.0055 14.9 0.0 0.0079 14.4 0.0 1.1 1 0 0 1 1 1 1 Spermatogenesis-associated, N-terminal tRNA-synt_1g PF09334.6 CBZ51634.1 - 8.1e-39 133.3 0.0 1.5e-23 83.1 0.0 6.0 6 0 0 6 6 6 6 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 CBZ51634.1 - 9.4e-06 23.9 0.0 0.0018 16.3 0.0 3.0 3 1 0 3 3 3 2 tRNA synthetases class I (I, L, M and V) DALR_1 PF05746.10 CBZ51634.1 - 0.031 14.2 0.0 0.08 12.8 0.0 1.6 1 0 0 1 1 1 0 DALR anticodon binding domain PAN_4 PF14295.1 CBZ51636.1 - 3e-32 110.0 29.6 2.8e-09 36.5 1.0 4.5 4 0 0 4 4 4 4 PAN domain PAN_1 PF00024.21 CBZ51636.1 - 3.7e-28 97.0 17.1 1.9e-08 33.9 0.2 4.3 4 0 0 4 4 4 4 PAN domain PAN_3 PF08277.7 CBZ51636.1 - 2.9e-09 36.4 18.3 0.011 15.3 0.6 4.2 4 0 0 4 4 4 4 PAN-like domain MANEC PF07502.9 CBZ51636.1 - 0.059 13.3 16.7 7.6 6.6 0.3 4.4 4 0 0 4 4 4 0 MANEC domain Sld5 PF05916.6 CBZ51637.1 - 1.3e-08 35.0 0.2 2.2e-08 34.3 0.1 1.3 1 0 0 1 1 1 1 GINS complex protein Guanylate_cyc_2 PF09778.4 CBZ51638.1 - 1.9e-25 89.3 0.0 6.1e-16 58.2 0.0 3.3 3 0 0 3 3 3 3 Guanylylate cyclase Peptidase_C39 PF03412.10 CBZ51638.1 - 0.00071 19.3 0.0 0.005 16.6 0.0 2.2 2 0 0 2 2 2 1 Peptidase C39 family Peptidase_C39_2 PF13529.1 CBZ51638.1 - 0.044 14.1 0.0 7.7 6.8 0.0 2.4 2 0 0 2 2 2 0 Peptidase_C39 like family Peptidase_S9_N PF02897.10 CBZ51639.1 - 8.8e-113 376.9 4.6 1.1e-112 376.6 3.2 1.1 1 0 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Peptidase_S9 PF00326.16 CBZ51639.1 - 4e-65 219.0 0.3 7e-65 218.2 0.0 1.5 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 CBZ51639.1 - 0.013 15.2 0.0 0.027 14.2 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family PD40 PF07676.7 CBZ51639.1 - 0.16 11.7 1.6 1.1 8.9 0.0 3.0 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat SUI1 PF01253.17 CBZ51641.1 - 1.1e-29 102.0 0.7 1.3e-29 101.7 0.5 1.1 1 0 0 1 1 1 1 Translation initiation factor SUI1 GTP_EFTU PF00009.22 CBZ51642.1 - 9.9e-41 139.2 0.0 1.5e-40 138.6 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 CBZ51642.1 - 1.3e-24 86.0 0.0 9e-24 83.3 0.0 2.1 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.19 CBZ51642.1 - 2.4e-20 72.1 0.0 6.1e-20 70.8 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus Miro PF08477.8 CBZ51642.1 - 1.2e-06 29.0 0.0 3.3e-06 27.5 0.0 1.8 2 0 0 2 2 1 1 Miro-like protein EFG_II PF14492.1 CBZ51642.1 - 2.4e-06 27.2 0.0 6.8e-06 25.8 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.20 CBZ51642.1 - 8.9e-06 25.7 0.7 2.9e-05 24.0 0.1 2.1 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 CBZ51642.1 - 4.2e-05 23.4 0.0 8.7e-05 22.4 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 CBZ51642.1 - 0.00061 19.6 0.0 0.79 9.5 0.0 2.4 1 1 1 2 2 2 2 Dynamin family Arf PF00025.16 CBZ51642.1 - 0.0026 17.0 0.0 1.2 8.3 0.0 3.1 3 0 0 3 3 3 1 ADP-ribosylation factor family SRPRB PF09439.5 CBZ51642.1 - 0.026 13.7 0.0 0.57 9.3 0.0 2.3 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_16 PF13191.1 CBZ51642.1 - 0.037 14.0 0.2 0.7 9.8 0.2 2.4 1 1 0 1 1 1 0 AAA ATPase domain Ras PF00071.17 CBZ51642.1 - 0.045 13.1 0.0 0.17 11.2 0.0 1.9 1 1 0 1 1 1 0 Ras family AAA_33 PF13671.1 CBZ51642.1 - 0.14 12.0 0.0 0.27 11.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain Pet191_N PF10203.4 CBZ51643.1 - 1e-19 70.3 4.8 1.1e-19 70.1 3.3 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 Cmc1 PF08583.5 CBZ51643.1 - 1.2 8.9 5.0 20 5.0 0.2 2.2 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like Mtc PF03820.12 CBZ51644.1 - 5.3e-66 222.3 0.0 6e-66 222.1 0.0 1.0 1 0 0 1 1 1 1 Tricarboxylate carrier Tic22 PF04278.7 CBZ51645.1 - 2e-16 60.1 0.3 7.7e-10 38.4 0.0 3.2 3 1 0 3 3 3 2 Tic22-like family Syndecan PF01034.15 CBZ51648.1 - 0.00044 19.8 0.3 0.00094 18.7 0.2 1.5 1 0 0 1 1 1 1 Syndecan domain DAP10 PF07213.6 CBZ51648.1 - 0.051 13.3 0.1 0.19 11.5 0.1 1.9 1 0 0 1 1 1 0 DAP10 membrane protein TMEM223 PF14640.1 CBZ51648.1 - 0.058 13.3 0.0 5 7.0 0.0 2.4 2 0 0 2 2 2 0 Transmembrane protein 223 EphA2_TM PF14575.1 CBZ51648.1 - 0.064 13.6 0.1 0.22 11.9 0.1 1.9 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF4059 PF13268.1 CBZ51648.1 - 0.072 13.2 0.1 0.18 11.9 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4059) Protocadherin PF08374.6 CBZ51648.1 - 0.085 12.4 0.2 0.085 12.4 0.2 1.9 2 0 0 2 2 2 0 Protocadherin DUF2269 PF10027.4 CBZ51648.1 - 0.096 12.4 0.3 1.1 9.0 0.0 2.2 2 0 0 2 2 2 0 Predicted integral membrane protein (DUF2269) Herpes_gE PF02480.11 CBZ51648.1 - 0.17 10.1 0.0 0.37 9.0 0.0 1.5 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E WBP-1 PF11669.3 CBZ51648.1 - 0.25 11.4 0.4 1.1 9.4 0.1 2.1 2 0 0 2 2 2 0 WW domain-binding protein 1 PsbW PF07123.7 CBZ51648.1 - 0.33 11.0 0.0 0.33 11.0 0.0 2.3 3 0 0 3 3 3 0 Photosystem II reaction centre W protein (PsbW) DUF2430 PF10353.4 CBZ51649.1 - 0.14 12.3 0.0 14 5.9 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2430) Baculo_PEP_C PF04513.7 CBZ51649.1 - 0.68 9.7 8.7 0.92 9.3 0.4 3.3 4 0 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Filamin PF00630.14 CBZ51650.1 - 1.8e-23 82.9 0.0 3.9e-13 49.8 0.0 2.5 2 0 0 2 2 2 2 Filamin/ABP280 repeat DUF4200 PF13863.1 CBZ51650.1 - 0.48 10.3 15.0 1 9.3 10.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) PGM_PMM_I PF02878.11 CBZ51651.1 - 2.7e-26 91.7 0.0 4.1e-26 91.1 0.0 1.3 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.11 CBZ51651.1 - 1.5e-24 86.1 0.0 4.1e-24 84.7 0.0 1.7 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.11 CBZ51651.1 - 1.2e-10 41.6 0.1 1.1e-09 38.5 0.0 2.7 3 0 0 3 3 3 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.15 CBZ51651.1 - 3.2e-06 27.0 0.0 7.9e-06 25.7 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain Acyl-ACP_TE PF01643.12 CBZ51651.1 - 0.13 11.2 0.2 0.2 10.5 0.1 1.2 1 0 0 1 1 1 0 Acyl-ACP thioesterase Ribosomal_S5 PF00333.15 CBZ51652.1 - 2.4e-07 30.4 0.0 4.5e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.10 CBZ51652.1 - 3.9e-06 26.0 0.0 2e-05 23.7 0.0 2.1 2 0 0 2 2 2 1 Ribosomal protein S5, C-terminal domain dsrm PF00035.20 CBZ51652.1 - 0.06 13.9 0.0 0.25 11.9 0.0 2.1 2 0 0 2 2 2 0 Double-stranded RNA binding motif NARP1 PF12569.3 CBZ51652.1 - 0.096 11.4 3.3 0.16 10.7 2.3 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Methyltrn_RNA_3 PF02598.12 CBZ51653.1 - 2.5e-72 243.6 0.0 3.7e-72 243.1 0.0 1.3 1 0 0 1 1 1 1 Putative RNA methyltransferase HAP2-GCS1 PF10699.4 CBZ51654.1 - 5.3e-13 48.7 0.0 1.5e-12 47.2 0.0 1.8 1 0 0 1 1 1 1 Male gamete fusion factor SAG PF04092.8 CBZ51658.1 - 1.9e-19 70.2 16.9 1.8e-13 50.9 2.1 2.1 2 0 0 2 2 2 2 SRS domain SAG PF04092.8 CBZ51659.1 - 4.2e-17 62.6 22.9 2.1e-13 50.7 3.5 2.4 2 1 0 2 2 2 2 SRS domain Env-gp36 PF09590.5 CBZ51659.1 - 0.014 13.5 3.6 0.42 8.7 0.8 2.2 1 1 1 2 2 2 0 Lentivirus surface glycoprotein FKBP_C PF00254.23 CBZ51660.1 - 4.1e-20 71.5 0.0 7.8e-20 70.6 0.0 1.5 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase RAP PF08373.5 CBZ51661.1 - 1.4e-23 82.3 0.3 2.3e-23 81.7 0.2 1.3 1 0 0 1 1 1 1 RAP domain MMtag PF10159.4 CBZ51661.1 - 0.051 13.6 0.6 0.051 13.6 0.4 1.8 2 0 0 2 2 2 0 Kinase phosphorylation protein Prefoldin PF02996.12 CBZ51661.1 - 0.075 12.6 0.1 0.16 11.6 0.1 1.5 1 0 0 1 1 1 0 Prefoldin subunit PPR PF01535.15 CBZ51662.1 - 0.00043 20.0 2.4 2 8.5 0.0 5.4 5 0 0 5 5 5 2 PPR repeat PPR_2 PF13041.1 CBZ51662.1 - 0.00065 19.6 0.0 14 5.7 0.0 5.7 6 0 0 6 6 6 1 PPR repeat family zf-MYND PF01753.13 CBZ51663.1 - 1.4e-07 31.2 5.4 3.3e-07 30.0 3.7 1.7 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.1 CBZ51663.1 - 0.47 10.3 3.4 1.5 8.7 2.4 1.8 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 SNF PF00209.13 CBZ51664.1 - 5.5e-15 54.8 18.1 5.4e-09 35.0 7.0 2.2 2 0 0 2 2 2 2 Sodium:neurotransmitter symporter family 60KD_IMP PF02096.15 CBZ51664.1 - 0.59 9.7 0.7 1.3 8.6 0.5 1.5 1 0 0 1 1 1 0 60Kd inner membrane protein Spc97_Spc98 PF04130.8 CBZ51666.1 - 5.3e-13 48.1 0.0 7e-07 27.9 0.0 2.9 3 1 0 3 3 3 2 Spc97 / Spc98 family CLAMP PF14769.1 CBZ51667.1 - 4.4e-30 103.8 3.8 6e-30 103.3 2.6 1.2 1 0 0 1 1 1 1 Flagellar C1a complex subunit C1a-32 Pro_isomerase PF00160.16 CBZ51668.1 - 5.4e-43 146.8 0.1 6.2e-43 146.6 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD adh_short PF00106.20 CBZ51669.1 - 5e-06 26.5 0.1 4.4e-05 23.4 0.1 2.3 1 1 0 1 1 1 1 short chain dehydrogenase Patatin PF01734.17 CBZ51669.1 - 0.11 12.4 0.1 0.14 12.0 0.0 1.2 1 0 0 1 1 1 0 Patatin-like phospholipase RabGAP-TBC PF00566.13 CBZ51670.1 - 2.7e-47 161.0 0.1 4.1e-47 160.4 0.1 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain ATP_bind_1 PF03029.12 CBZ51671.1 - 1.3e-74 250.7 0.0 1.7e-74 250.3 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein CbiA PF01656.18 CBZ51671.1 - 3.7e-10 39.5 0.0 6.9e-10 38.6 0.0 1.6 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain SRP54 PF00448.17 CBZ51671.1 - 1.3e-05 24.7 2.5 0.001 18.5 0.1 2.8 3 0 0 3 3 3 1 SRP54-type protein, GTPase domain AAA_33 PF13671.1 CBZ51671.1 - 1.6e-05 24.7 0.1 0.00011 22.1 0.0 2.1 2 0 0 2 2 2 1 AAA domain ArgK PF03308.11 CBZ51671.1 - 3.7e-05 22.6 0.6 0.00028 19.7 0.2 2.4 2 1 0 2 2 2 1 ArgK protein MobB PF03205.9 CBZ51671.1 - 4.3e-05 23.2 0.2 0.00018 21.2 0.0 2.0 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B GTP_EFTU PF00009.22 CBZ51671.1 - 0.00015 21.2 0.0 0.0016 17.9 0.0 2.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain NTPase_1 PF03266.10 CBZ51671.1 - 0.00028 20.6 0.0 0.00063 19.4 0.0 1.6 1 0 0 1 1 1 1 NTPase AAA_30 PF13604.1 CBZ51671.1 - 0.00029 20.4 0.1 0.00029 20.4 0.0 1.9 2 0 0 2 2 2 1 AAA domain cobW PF02492.14 CBZ51671.1 - 0.00032 20.1 0.0 0.074 12.4 0.1 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_31 PF13614.1 CBZ51671.1 - 0.00037 20.4 0.0 0.004 17.0 0.0 2.4 1 1 0 1 1 1 1 AAA domain AAA_10 PF12846.2 CBZ51671.1 - 0.00058 19.3 0.1 0.0017 17.8 0.0 1.7 2 0 0 2 2 2 1 AAA-like domain MMR_HSR1 PF01926.18 CBZ51671.1 - 0.0025 17.7 0.0 0.0081 16.1 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase MipZ PF09140.6 CBZ51671.1 - 0.0046 16.0 0.0 0.0098 15.0 0.0 1.5 1 1 0 1 1 1 1 ATPase MipZ FeoB_N PF02421.13 CBZ51671.1 - 0.005 16.1 0.0 0.035 13.3 0.0 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B AAA_16 PF13191.1 CBZ51671.1 - 0.0051 16.8 0.1 0.035 14.0 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain NACHT PF05729.7 CBZ51671.1 - 0.0054 16.4 0.5 0.013 15.1 0.1 1.9 2 0 0 2 2 1 1 NACHT domain KTI12 PF08433.5 CBZ51671.1 - 0.0055 15.9 0.1 0.015 14.5 0.0 1.7 2 0 0 2 2 2 1 Chromatin associated protein KTI12 AAA_24 PF13479.1 CBZ51671.1 - 0.008 15.7 0.0 0.014 14.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain T2SE PF00437.15 CBZ51671.1 - 0.0091 14.9 0.0 0.015 14.2 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_17 PF13207.1 CBZ51671.1 - 0.012 16.4 0.0 0.026 15.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 CBZ51671.1 - 0.03 14.4 0.0 0.066 13.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain APS_kinase PF01583.15 CBZ51671.1 - 0.032 13.9 0.0 0.054 13.1 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase Pox_A32 PF04665.7 CBZ51671.1 - 0.035 13.4 0.1 0.068 12.4 0.1 1.5 1 0 0 1 1 1 0 Poxvirus A32 protein NB-ARC PF00931.17 CBZ51671.1 - 0.036 12.9 0.9 0.066 12.0 0.6 1.4 1 0 0 1 1 1 0 NB-ARC domain Dynamin_N PF00350.18 CBZ51671.1 - 0.038 13.7 0.3 0.12 12.2 0.0 1.9 2 1 0 2 2 1 0 Dynamin family UPF0079 PF02367.12 CBZ51671.1 - 0.05 13.2 0.2 0.11 12.1 0.1 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 RNA_helicase PF00910.17 CBZ51671.1 - 0.078 13.1 0.0 1.1 9.5 0.0 2.3 2 0 0 2 2 2 0 RNA helicase ArsA_ATPase PF02374.10 CBZ51671.1 - 0.087 11.8 0.3 0.64 9.0 0.0 2.3 3 0 0 3 3 3 0 Anion-transporting ATPase AAA_18 PF13238.1 CBZ51671.1 - 0.1 12.9 0.0 0.25 11.6 0.0 1.7 1 1 0 1 1 1 0 AAA domain Zot PF05707.7 CBZ51671.1 - 0.11 11.9 0.0 0.29 10.5 0.0 1.7 2 0 0 2 2 2 0 Zonular occludens toxin (Zot) AAA_14 PF13173.1 CBZ51671.1 - 0.12 12.2 0.0 0.3 10.9 0.0 1.7 2 0 0 2 2 1 0 AAA domain AAA_23 PF13476.1 CBZ51671.1 - 0.15 12.3 0.6 3.5 7.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain LpxK PF02606.9 CBZ51671.1 - 0.16 10.9 0.7 0.24 10.2 0.0 1.6 2 0 0 2 2 2 0 Tetraacyldisaccharide-1-P 4'-kinase OAD_gamma PF04277.8 CBZ51671.1 - 0.22 11.9 1.6 0.42 11.0 1.1 1.5 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain DUF463 PF04317.7 CBZ51671.1 - 0.55 8.7 2.8 0.94 7.9 0.0 2.4 2 1 1 3 3 3 0 YcjX-like family, DUF463 4HBT PF03061.17 CBZ51672.1 - 6.3e-05 23.0 0.2 0.00021 21.3 0.1 2.0 2 0 0 2 2 2 1 Thioesterase superfamily UFD1 PF03152.9 CBZ51673.1 - 4.9e-19 68.1 0.0 3.9e-16 58.6 0.0 2.1 2 0 0 2 2 2 2 Ubiquitin fusion degradation protein UFD1 Notch PF00066.12 CBZ51674.1 - 3.9e-51 171.0 111.2 6e-10 39.2 8.1 6.2 4 1 2 6 6 6 6 LNR domain Biotin_lipoyl PF00364.17 CBZ51675.1 - 2.7e-19 68.5 0.9 4.1e-19 67.9 0.6 1.3 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.1 CBZ51675.1 - 0.00091 18.8 0.7 0.0017 17.9 0.2 1.6 1 1 1 2 2 2 1 Biotin-lipoyl like HlyD PF00529.15 CBZ51675.1 - 0.037 13.3 0.7 0.047 12.9 0.5 1.1 1 0 0 1 1 1 0 HlyD family secretion protein HlyD_2 PF12700.2 CBZ51675.1 - 0.22 10.6 0.5 2.2 7.3 0.1 1.9 1 1 1 2 2 2 0 HlyD family secretion protein Peptidase_M50B PF13398.1 CBZ51676.1 - 5.4e-57 192.4 22.6 6.6e-57 192.1 15.7 1.1 1 0 0 1 1 1 1 Peptidase M50B-like DSHCT PF08148.7 CBZ51677.1 - 1.9e-49 167.3 0.1 5.1e-49 165.9 0.0 1.8 2 0 0 2 2 2 1 DSHCT (NUC185) domain DEAD PF00270.24 CBZ51677.1 - 1.6e-17 63.5 0.0 3.1e-17 62.5 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CBZ51677.1 - 6.1e-06 26.0 0.1 1.3e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 CBZ51677.1 - 0.0027 17.5 0.0 0.047 13.5 0.0 2.6 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit EMP24_GP25L PF01105.19 CBZ51678.1 - 1.5 8.5 1.3 34 4.0 0.0 2.4 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD DUF904 PF06005.7 CBZ51678.1 - 6.4 7.1 13.4 0.24 11.6 4.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF904) PAP_assoc PF03828.14 CBZ51679.1 - 3.9e-08 33.1 0.0 9.7e-08 31.8 0.0 1.7 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 CBZ51679.1 - 0.0019 18.4 0.0 0.0082 16.4 0.0 2.0 2 0 0 2 2 2 1 Nucleotidyltransferase domain LCD1 PF09798.4 CBZ51679.1 - 1 7.2 0.3 1.5 6.6 0.2 1.1 1 0 0 1 1 1 0 DNA damage checkpoint protein Ribosomal_L35p PF01632.14 CBZ51680.1 - 2.6e-15 56.0 6.5 5.2e-15 55.0 4.5 1.4 1 0 0 1 1 1 1 Ribosomal protein L35 Methyltransf_15 PF09445.5 CBZ51681.1 - 7.7e-29 100.3 0.0 1.2e-28 99.7 0.0 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Cmc1 PF08583.5 CBZ51682.1 - 0.012 15.3 2.0 0.012 15.3 1.4 2.4 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like CHCH PF06747.8 CBZ51682.1 - 0.024 14.5 12.0 0.13 12.2 1.8 2.6 2 1 0 2 2 2 0 CHCH domain UPF0203 PF05254.7 CBZ51682.1 - 0.67 9.8 5.8 0.59 10.0 0.2 2.7 1 1 2 3 3 3 0 Uncharacterised protein family (UPF0203) Pet191_N PF10203.4 CBZ51682.1 - 2.3 8.3 9.3 15 5.7 0.1 2.2 2 0 0 2 2 2 0 Cytochrome c oxidase assembly protein PET191 COX6B PF02297.12 CBZ51682.1 - 4 7.5 8.2 13 5.8 5.7 1.8 1 1 0 1 1 1 0 Cytochrome oxidase c subunit VIb COX17 PF05051.8 CBZ51682.1 - 6.9 6.7 6.8 0.58 10.2 0.2 2.3 2 1 0 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) Caveolin PF01146.12 CBZ51683.1 - 0.034 13.7 0.4 0.078 12.5 0.0 1.7 2 0 0 2 2 2 0 Caveolin PRT_C PF08372.5 CBZ51684.1 - 0.0071 15.8 0.0 0.014 14.8 0.0 1.4 1 0 0 1 1 1 1 Plant phosphoribosyltransferase C-terminal HHH PF00633.18 CBZ51685.1 - 5.4e-06 25.8 0.0 1.6e-05 24.3 0.0 1.9 1 0 0 1 1 1 1 Helix-hairpin-helix motif HhH-GPD PF00730.20 CBZ51685.1 - 2.4e-05 24.5 0.0 0.00022 21.4 0.0 2.4 2 1 0 2 2 2 1 HhH-GPD superfamily base excision DNA repair protein CASP_C PF08172.7 CBZ51686.1 - 0.43 9.5 5.4 1 8.2 3.8 1.6 1 0 0 1 1 1 0 CASP C terminal Patched PF02460.13 CBZ51687.1 - 2.7e-98 329.8 11.8 9.9e-52 175.9 0.0 2.8 2 1 0 2 2 2 2 Patched family Sterol-sensing PF12349.3 CBZ51687.1 - 1.1e-31 109.3 7.7 1.1e-31 109.3 5.3 2.4 2 0 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation Cullin PF00888.17 CBZ51688.1 - 1e-08 34.2 0.0 8.8e-06 24.5 0.0 2.1 2 0 0 2 2 2 2 Cullin family Kinesin PF00225.18 CBZ51692.1 - 6.9e-99 330.7 0.7 1.3e-98 329.8 0.0 1.8 2 0 0 2 2 2 1 Kinesin motor domain Fer2_BFD PF04324.10 CBZ51692.1 - 0.088 12.8 0.1 0.47 10.5 0.0 2.3 1 0 0 1 1 1 0 BFD-like [2Fe-2S] binding domain CENP-Q PF13094.1 CBZ51692.1 - 0.2 11.6 62.6 0.025 14.6 17.1 5.8 4 2 1 5 5 5 0 CENP-Q, a CENPA-CAD centromere complex subunit LRR_4 PF12799.2 CBZ51693.1 - 1.5e-14 53.1 9.2 9.8e-09 34.6 0.0 4.2 4 1 0 4 4 4 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 CBZ51693.1 - 5.6e-08 31.7 7.4 0.61 10.3 0.0 4.9 5 0 0 5 5 5 4 Leucine Rich Repeat LRR_8 PF13855.1 CBZ51693.1 - 7.2e-07 28.8 7.1 0.0055 16.4 0.0 3.4 3 1 0 3 3 3 2 Leucine rich repeat LRR_7 PF13504.1 CBZ51693.1 - 1.5e-05 24.4 5.2 2.7 8.5 0.0 5.0 4 1 1 5 5 5 2 Leucine rich repeat LRR_6 PF13516.1 CBZ51693.1 - 0.00062 19.5 8.4 1.9 8.7 0.0 4.7 4 1 1 5 5 5 2 Leucine Rich repeat LRR_9 PF14580.1 CBZ51693.1 - 0.016 14.8 0.2 0.48 9.9 0.0 2.1 1 1 1 2 2 2 0 Leucine-rich repeat HTH_Tnp_1 PF01527.15 CBZ51694.1 - 1.9e-05 24.4 0.0 6.2e-05 22.8 0.0 1.9 1 0 0 1 1 1 1 Transposase HTH_23 PF13384.1 CBZ51694.1 - 0.00012 21.6 4.7 0.00023 20.7 0.1 2.8 2 1 0 2 2 2 1 Homeodomain-like domain HTH_17 PF12728.2 CBZ51694.1 - 0.00042 20.4 5.5 0.054 13.7 0.0 3.6 3 1 1 4 4 4 1 Helix-turn-helix domain MerR_1 PF13411.1 CBZ51694.1 - 0.00055 19.6 0.2 0.021 14.5 0.0 2.4 2 0 0 2 2 2 1 MerR HTH family regulatory protein HTH_28 PF13518.1 CBZ51694.1 - 0.0057 16.6 1.5 0.27 11.3 0.0 2.7 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_Tnp_Tc5 PF03221.11 CBZ51694.1 - 0.0088 15.8 0.4 0.025 14.3 0.3 1.8 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain MerR PF00376.18 CBZ51694.1 - 0.016 14.7 0.0 0.037 13.5 0.0 1.6 1 0 0 1 1 1 0 MerR family regulatory protein CENP-B_N PF04218.8 CBZ51694.1 - 0.033 13.6 10.2 0.52 9.7 0.0 3.8 4 0 0 4 4 4 0 CENP-B N-terminal DNA-binding domain HTH_DeoR PF08220.7 CBZ51694.1 - 0.057 12.9 0.1 0.16 11.5 0.0 1.7 2 0 0 2 2 2 0 DeoR-like helix-turn-helix domain HTH_19 PF12844.2 CBZ51694.1 - 0.12 12.4 1.0 0.68 10.0 0.0 2.7 3 1 0 3 3 3 0 Helix-turn-helix domain HTH_31 PF13560.1 CBZ51694.1 - 0.25 11.5 7.6 1.3 9.2 0.2 3.6 1 1 2 3 3 3 0 Helix-turn-helix domain Fasciclin PF02469.17 CBZ51696.1 - 2.2e-11 43.8 0.0 0.00025 21.0 0.0 3.2 3 0 0 3 3 3 3 Fasciclin domain DUF3363 PF11843.3 CBZ51696.1 - 0.031 12.9 0.3 0.043 12.4 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3363) DnaJ PF00226.26 CBZ51697.1 - 5.8e-20 70.7 0.3 1.7e-19 69.3 0.2 1.9 1 0 0 1 1 1 1 DnaJ domain DUF4460 PF14687.1 CBZ51697.1 - 0.056 13.2 1.2 0.15 11.8 0.8 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4460) DUF763 PF05559.6 CBZ51697.1 - 0.94 8.3 5.8 1.7 7.5 4.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF763) DUF2422 PF10337.4 CBZ51697.1 - 1.5 7.5 7.1 2.7 6.6 4.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2422) DUF2229 PF09989.4 CBZ51697.1 - 6 6.2 8.6 12 5.2 5.5 1.8 1 1 1 2 2 2 0 CoA enzyme activase uncharacterised domain (DUF2229) DUF4168 PF13767.1 CBZ51697.1 - 7 7.3 10.3 1.7 9.3 1.8 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4168) DAP PF15228.1 CBZ51699.1 - 0.89 10.3 3.1 1.8 9.3 0.3 2.4 2 0 0 2 2 2 0 Death-associated protein Steroid_dh PF02544.11 CBZ51700.1 - 4.9e-33 114.0 1.6 9.6e-33 113.0 1.1 1.5 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase ubiquitin PF00240.18 CBZ51700.1 - 6.6e-05 22.2 0.0 0.00012 21.4 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family YukD PF08817.5 CBZ51700.1 - 0.00027 21.4 0.0 0.00042 20.8 0.0 1.4 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukD PRP38 PF03371.10 CBZ51701.1 - 5.5e-46 156.3 0.3 7.8e-46 155.8 0.2 1.2 1 0 0 1 1 1 1 PRP38 family CAP_GLY PF01302.20 CBZ51702.1 - 1.3e-15 56.7 0.1 3.8e-15 55.3 0.1 1.7 1 0 0 1 1 1 1 CAP-Gly domain LRR_4 PF12799.2 CBZ51702.1 - 1.2e-07 31.1 4.9 0.081 12.5 0.5 4.6 3 1 1 4 4 4 4 Leucine Rich repeats (2 copies) Ubiquitin_2 PF14560.1 CBZ51702.1 - 5.4e-07 29.7 0.0 1e-06 28.8 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-like domain LRR_1 PF00560.28 CBZ51702.1 - 0.0072 16.2 4.9 14 6.1 0.0 5.6 5 1 0 5 5 5 1 Leucine Rich Repeat HRDC PF00570.18 CBZ51702.1 - 0.071 12.8 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 HRDC domain LRR_7 PF13504.1 CBZ51702.1 - 0.16 12.3 6.7 55 4.6 0.0 5.6 5 0 0 5 5 5 0 Leucine rich repeat LRR_8 PF13855.1 CBZ51702.1 - 0.18 11.5 4.1 37 4.1 0.7 4.3 4 0 0 4 4 4 0 Leucine rich repeat LRR_6 PF13516.1 CBZ51702.1 - 0.49 10.6 6.7 40 4.7 0.0 5.5 6 0 0 6 6 6 0 Leucine Rich repeat AbiH PF14253.1 CBZ51703.1 - 0.24 10.9 1.4 0.41 10.1 0.9 1.2 1 0 0 1 1 1 0 Bacteriophage abortive infection AbiH Baculo_PEP_C PF04513.7 CBZ51703.1 - 2 8.2 9.7 6.5 6.5 0.0 2.9 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Beta-Casp PF10996.3 CBZ51704.1 - 1.6e-27 95.9 0.0 2.8e-27 95.1 0.0 1.4 1 0 0 1 1 1 1 Beta-Casp domain CPSF73-100_C PF11718.3 CBZ51704.1 - 5.2e-18 65.2 0.0 1.4e-15 57.2 0.0 2.3 2 0 0 2 2 2 2 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Lactamase_B PF00753.22 CBZ51704.1 - 4.3e-13 49.3 0.6 3.2e-12 46.5 0.4 2.2 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily RMMBL PF07521.7 CBZ51704.1 - 1.2e-10 41.0 0.0 2.3e-10 40.1 0.0 1.5 1 0 0 1 1 1 1 RNA-metabolising metallo-beta-lactamase Lactamase_B_2 PF12706.2 CBZ51704.1 - 9.3e-10 38.3 0.0 2.2e-09 37.1 0.0 1.6 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 CBZ51704.1 - 0.00018 21.2 0.0 0.00059 19.5 0.0 1.7 1 1 0 1 1 1 1 Beta-lactamase superfamily domain zf-RING_2 PF13639.1 CBZ51705.1 - 2.3e-13 49.7 7.8 4.2e-13 48.8 5.4 1.5 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 CBZ51705.1 - 1.5e-09 37.8 3.9 1.5e-09 37.8 2.7 1.7 2 0 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 CBZ51705.1 - 3.5e-06 26.5 6.5 6.3e-06 25.7 4.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CBZ51705.1 - 1.7e-05 24.7 6.5 4.3e-05 23.4 4.5 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 CBZ51705.1 - 6.8e-05 22.6 1.4 0.00014 21.6 0.9 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.1 CBZ51705.1 - 0.00014 21.5 5.8 0.00039 20.0 4.0 1.8 1 0 0 1 1 1 1 zinc-RING finger domain FANCL_C PF11793.3 CBZ51705.1 - 0.00027 20.8 3.1 0.00072 19.4 2.2 1.8 1 0 0 1 1 1 1 FANCL C-terminal domain zf-C3HC4_3 PF13920.1 CBZ51705.1 - 0.0025 17.4 3.8 0.0025 17.4 2.6 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-Nse PF11789.3 CBZ51705.1 - 0.038 13.5 2.5 0.073 12.5 1.7 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit TF_Zn_Ribbon PF08271.7 CBZ51705.1 - 0.039 13.2 0.5 0.039 13.2 0.3 1.9 2 0 0 2 2 2 0 TFIIB zinc-binding Pex19 PF04614.7 CBZ51705.1 - 0.094 12.3 0.5 0.38 10.3 0.1 2.1 2 0 0 2 2 2 0 Pex19 protein family Rad50_zn_hook PF04423.9 CBZ51705.1 - 0.2 11.1 0.1 0.55 9.7 0.1 1.7 1 0 0 1 1 1 0 Rad50 zinc hook motif RINGv PF12906.2 CBZ51705.1 - 3.4 7.7 7.5 7 6.7 5.2 1.5 1 0 0 1 1 1 0 RING-variant domain S1-P1_nuclease PF02265.11 CBZ51706.1 - 2.6e-28 99.3 0.0 1.4e-17 64.1 0.0 2.6 2 1 0 2 2 2 2 S1/P1 Nuclease Methyltransf_26 PF13659.1 CBZ51707.1 - 3.7e-06 26.9 0.8 9.5e-06 25.6 0.0 2.1 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_18 PF12847.2 CBZ51707.1 - 0.0024 18.4 0.0 0.0059 17.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Pkinase PF00069.20 CBZ51708.1 - 9e-76 254.4 0.0 1.1e-75 254.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ51708.1 - 1e-29 103.3 0.0 1.4e-29 103.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CBZ51708.1 - 0.0083 15.8 0.1 0.058 13.1 0.0 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.1 CBZ51708.1 - 0.011 14.7 0.0 0.019 13.9 0.0 1.6 2 0 0 2 2 2 0 Kinase-like Kdo PF06293.9 CBZ51708.1 - 0.047 12.7 0.2 0.2 10.6 0.1 1.8 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 CBZ51708.1 - 0.071 12.6 0.0 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase Pox_ser-thr_kin PF05445.6 CBZ51708.1 - 0.098 11.4 0.0 0.18 10.5 0.0 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase IQ PF00612.22 CBZ51709.1 - 0.00047 19.5 0.3 0.0012 18.2 0.2 1.8 1 0 0 1 1 1 1 IQ calmodulin-binding motif Corona_nucleoca PF00937.13 CBZ51709.1 - 5.8 5.7 25.7 0.11 11.4 4.1 2.9 3 0 0 3 3 3 0 Coronavirus nucleocapsid protein AroM PF07302.6 CBZ51710.1 - 9.2 5.5 13.3 2.8e+02 0.6 0.0 8.6 10 1 0 11 11 11 0 AroM protein FUSC_2 PF13515.1 CBZ51711.1 - 3.5e-10 39.8 25.6 7.6e-10 38.7 9.7 3.0 2 1 0 2 2 2 2 Fusaric acid resistance protein-like ALMT PF11744.3 CBZ51711.1 - 0.0074 14.9 5.2 0.0075 14.9 2.0 2.0 2 0 0 2 2 2 1 Aluminium activated malate transporter DUF285 PF03382.9 CBZ51712.1 - 0.097 12.2 2.9 0.077 12.5 0.5 1.8 2 0 0 2 2 2 0 Mycoplasma protein of unknown function, DUF285 Ribosomal_S6 PF01250.12 CBZ51713.1 - 7.5e-13 48.1 0.0 1e-12 47.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S6 DUF707 PF05212.7 CBZ51713.1 - 0.042 12.9 0.2 0.089 11.8 0.0 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF707) zf-met2 PF12907.2 CBZ51715.1 - 6.9e-16 57.9 4.5 9.1e-16 57.5 3.1 1.2 1 0 0 1 1 1 1 Zinc-binding 4F5 PF04419.9 CBZ51715.1 - 2.7e-09 37.5 4.0 3.9e-09 37.1 2.7 1.2 1 0 0 1 1 1 1 4F5 protein family zf-Di19 PF05605.7 CBZ51715.1 - 0.48 10.5 3.4 3.6 7.7 2.0 2.0 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding LRR_6 PF13516.1 CBZ51716.1 - 0.6 10.3 9.3 20 5.6 0.0 6.2 7 0 0 7 7 7 0 Leucine Rich repeat DUF4254 PF14063.1 CBZ51717.1 - 0.026 14.1 0.3 0.056 13.0 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF4254) E1-E2_ATPase PF00122.15 CBZ51718.1 - 2.6e-33 114.9 0.3 2.6e-33 114.9 0.2 3.1 4 1 0 4 4 4 1 E1-E2 ATPase Hydrolase PF00702.21 CBZ51718.1 - 1.1e-23 84.7 0.2 2e-23 83.9 0.1 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 CBZ51718.1 - 4.4e-13 49.8 0.0 1e-12 48.6 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 CBZ51718.1 - 9.7e-08 31.3 0.0 2.8e-07 29.8 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 CBZ51718.1 - 5.4e-06 26.1 0.4 2.3e-05 24.1 0.2 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 CBZ51718.1 - 0.037 13.9 0.0 0.077 12.9 0.0 1.5 1 0 0 1 1 1 0 Putative hydrolase of sodium-potassium ATPase alpha subunit Med10 PF09748.4 CBZ51719.1 - 0.00088 19.0 0.0 0.0015 18.3 0.0 1.4 1 0 0 1 1 1 1 Transcription factor subunit Med10 of Mediator complex Pribosyltran_N PF13793.1 CBZ51720.1 - 3.9e-29 100.7 0.0 1.8e-28 98.5 0.0 2.0 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.1 CBZ51720.1 - 1.1e-27 97.0 0.0 1.8e-27 96.2 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 CBZ51720.1 - 0.00041 20.0 0.0 0.0011 18.6 0.0 1.7 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Ribosomal_L6 PF00347.18 CBZ51722.1 - 1.8e-31 108.4 1.3 1.5e-15 57.4 0.0 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 EF-hand_7 PF13499.1 CBZ51723.1 - 3.9e-42 142.2 8.8 1.4e-11 44.3 0.2 8.1 8 0 0 8 8 8 5 EF-hand domain pair EF-hand_1 PF00036.27 CBZ51723.1 - 1.6e-26 89.5 15.3 3e-07 29.2 0.1 10.0 11 0 0 11 11 11 6 EF hand EF-hand_8 PF13833.1 CBZ51723.1 - 2.6e-26 90.9 4.2 1.6e-07 30.8 0.0 7.8 7 2 1 8 8 8 4 EF-hand domain pair EF-hand_6 PF13405.1 CBZ51723.1 - 2.4e-25 86.0 20.0 3.6e-07 29.5 0.1 10.7 11 0 0 11 11 11 5 EF-hand domain EF-hand_5 PF13202.1 CBZ51723.1 - 2.6e-08 32.8 27.1 0.00016 20.8 0.1 7.1 8 0 0 8 8 8 3 EF hand EF-hand_9 PF14658.1 CBZ51723.1 - 2.9e-06 27.1 0.0 14 5.6 0.0 5.6 5 0 0 5 5 5 2 EF-hand domain EF-hand_10 PF14788.1 CBZ51723.1 - 0.079 12.6 2.8 0.27 10.9 0.1 2.9 3 0 0 3 3 3 0 EF hand OSCP PF00213.13 CBZ51724.1 - 1.5e-47 161.6 2.3 1.8e-47 161.4 1.6 1.1 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit IRK PF01007.15 CBZ51725.1 - 2.1e-18 66.2 1.9 2.1e-10 39.9 1.2 2.1 2 0 0 2 2 2 2 Inward rectifier potassium channel Ion_trans_2 PF07885.11 CBZ51725.1 - 0.0083 15.8 4.8 0.014 15.0 3.3 1.4 1 0 0 1 1 1 1 Ion channel PK PF00224.16 CBZ51726.1 - 2.4e-143 476.9 0.5 3.7e-143 476.3 0.4 1.3 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.11 CBZ51726.1 - 6.7e-30 103.0 3.8 2.5e-29 101.1 2.7 2.1 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.9 CBZ51726.1 - 0.00044 19.2 0.8 0.0017 17.2 0.0 2.2 2 0 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family DEAD PF00270.24 CBZ51727.1 - 6.6e-41 139.6 0.0 3.2e-40 137.3 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CBZ51727.1 - 5.3e-29 99.8 0.2 1.5e-28 98.4 0.1 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_19 PF13245.1 CBZ51727.1 - 0.00081 19.0 0.0 0.0038 16.9 0.0 2.0 1 1 1 2 2 2 1 Part of AAA domain ResIII PF04851.10 CBZ51727.1 - 0.031 14.0 0.0 0.14 11.9 0.0 2.0 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_22 PF13401.1 CBZ51727.1 - 0.035 14.2 0.2 0.22 11.6 0.2 2.2 1 1 0 1 1 1 0 AAA domain Peptidase_C5 PF00770.13 CBZ51727.1 - 0.036 13.6 0.0 0.061 12.8 0.0 1.3 1 0 0 1 1 1 0 Adenovirus endoprotease AAA_30 PF13604.1 CBZ51727.1 - 0.086 12.4 0.0 0.95 9.0 0.0 2.3 1 1 0 1 1 1 0 AAA domain Peptidase_C97 PF05903.9 CBZ51728.1 - 8.5e-32 110.0 0.0 1.2e-31 109.5 0.0 1.2 1 0 0 1 1 1 1 PPPDE putative peptidase domain PepSY_TM_2 PF13703.1 CBZ51729.1 - 0.017 15.2 0.0 0.036 14.2 0.0 1.5 1 0 0 1 1 1 0 PepSY-associated TM helix TctB PF07331.6 CBZ51729.1 - 0.039 13.5 0.3 1.3 8.6 0.4 2.2 2 0 0 2 2 2 0 Tripartite tricarboxylate transporter TctB family DnaJ PF00226.26 CBZ51730.1 - 2.5e-21 75.1 2.5 5.9e-21 73.9 1.7 1.7 1 0 0 1 1 1 1 DnaJ domain DUF2855 PF11017.3 CBZ51730.1 - 0.77 8.8 4.2 6.2 5.8 1.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2855) WD40 PF00400.27 CBZ51731.1 - 1.5e-07 30.9 4.0 0.1 12.5 0.0 3.8 4 0 0 4 4 4 3 WD domain, G-beta repeat zf-CCCH PF00642.19 CBZ51731.1 - 5.5e-06 25.9 4.5 1.2e-05 24.8 3.1 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 CBZ51731.1 - 0.069 13.1 2.1 0.17 11.9 1.4 1.7 1 1 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type Syja_N PF02383.13 CBZ51732.1 - 8e-21 74.1 0.0 2.8e-17 62.4 0.0 3.4 2 1 0 2 2 2 2 SacI homology domain DUF829 PF05705.9 CBZ51733.1 - 0.00067 19.4 0.0 0.0017 18.1 0.0 1.7 2 0 0 2 2 2 1 Eukaryotic protein of unknown function (DUF829) SIR2 PF02146.12 CBZ51734.1 - 8.4e-07 28.8 0.1 0.031 14.0 0.0 4.0 5 0 0 5 5 5 2 Sir2 family RRM_1 PF00076.17 CBZ51735.1 - 3.7e-16 58.5 0.0 7.3e-16 57.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBZ51735.1 - 7.3e-13 48.2 0.0 2.1e-12 46.8 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) CSTF2_hinge PF14327.1 CBZ51735.1 - 9.1e-10 38.4 0.0 2.1e-09 37.2 0.0 1.6 1 0 0 1 1 1 1 Hinge domain of cleavage stimulation factor subunit 2 RRM_5 PF13893.1 CBZ51735.1 - 3.6e-09 36.3 0.0 5.5e-09 35.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Presenilin PF01080.12 CBZ51735.1 - 0.34 9.6 0.1 0.5 9.1 0.1 1.1 1 0 0 1 1 1 0 Presenilin EMP70 PF02990.11 CBZ51736.1 - 5.9e-134 447.3 0.2 5.9e-134 447.3 0.2 1.6 2 0 0 2 2 2 1 Endomembrane protein 70 PTPA PF03095.10 CBZ51737.1 - 5e-97 324.6 0.0 9.5e-96 320.4 0.0 2.0 1 1 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein TRAM_LAG1_CLN8 PF03798.11 CBZ51738.1 - 1.7e-28 99.5 16.9 2.7e-28 98.8 11.7 1.3 1 0 0 1 1 1 1 TLC domain PI3_PI4_kinase PF00454.22 CBZ51739.1 - 1e-23 84.0 0.0 2e-23 83.1 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.15 CBZ51739.1 - 3.8e-08 32.6 0.1 9.5e-08 31.3 0.1 1.7 1 0 0 1 1 1 1 FATC domain CENP-T PF15511.1 CBZ51741.1 - 2 7.5 39.0 2.4 7.2 27.0 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T NIF PF03031.13 CBZ51742.1 - 8.9e-17 61.1 0.0 1.3e-16 60.7 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase DnaJ PF00226.26 CBZ51743.1 - 7.1e-15 54.5 0.1 1.1e-09 37.9 0.0 2.5 2 0 0 2 2 2 2 DnaJ domain HMA PF00403.21 CBZ51745.1 - 0.086 13.0 0.1 0.41 10.8 0.1 2.1 2 0 0 2 2 2 0 Heavy-metal-associated domain Ras PF00071.17 CBZ51746.1 - 1.1e-31 109.4 0.5 1.3e-31 109.1 0.3 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CBZ51746.1 - 4.9e-17 62.5 0.1 5.7e-17 62.3 0.0 1.0 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 CBZ51746.1 - 1.4e-07 31.4 0.0 1.7e-07 31.1 0.0 1.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.16 CBZ51746.1 - 7.5e-07 28.5 0.1 9.2e-07 28.2 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family DUF258 PF03193.11 CBZ51746.1 - 0.012 14.7 0.1 0.02 14.1 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function, DUF258 PduV-EutP PF10662.4 CBZ51746.1 - 0.022 14.2 0.1 0.035 13.6 0.0 1.3 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Gtr1_RagA PF04670.7 CBZ51746.1 - 0.042 12.9 0.0 0.051 12.7 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_14 PF13173.1 CBZ51746.1 - 0.085 12.7 0.1 0.099 12.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 CBZ51746.1 - 0.12 12.1 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 Archaeal ATPase DUF4218 PF13960.1 CBZ51747.1 - 0.1 12.0 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4218) Pro_isomerase PF00160.16 CBZ51748.1 - 1.1e-40 139.3 0.0 1.4e-40 138.9 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Ribosomal_L23 PF00276.15 CBZ51749.1 - 2.1e-18 66.0 0.5 2.1e-18 66.0 0.4 2.2 2 1 0 2 2 2 1 Ribosomal protein L23 Ribosomal_L23eN PF03939.8 CBZ51749.1 - 1.5e-05 24.9 24.3 1.6e-05 24.8 14.0 2.6 2 1 0 2 2 2 1 Ribosomal protein L23, N-terminal domain Levi_coat PF01819.12 CBZ51749.1 - 5.5e-05 22.7 1.3 0.054 13.0 0.2 2.2 1 1 1 2 2 2 2 Levivirus coat protein TusA PF01206.12 CBZ51749.1 - 0.014 14.9 0.1 0.53 9.9 0.1 2.3 1 1 1 2 2 2 0 Sulfurtransferase TusA Elong-fact-P_C PF09285.6 CBZ51749.1 - 0.021 14.1 0.1 0.054 12.8 0.0 1.7 1 0 0 1 1 1 0 Elongation factor P, C-terminal NAM-associated PF14303.1 CBZ51749.1 - 0.32 11.3 0.0 0.32 11.3 0.0 2.0 1 1 1 2 2 2 0 No apical meristem-associated C-terminal domain Thioredoxin PF00085.15 CBZ51751.1 - 1.4e-210 683.3 17.8 8.4e-24 83.2 0.0 10.2 10 0 0 10 10 10 10 Thioredoxin Glyco_transf_90 PF05686.7 CBZ51751.1 - 1.8e-63 214.5 0.0 2.9e-63 213.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 90 Thioredoxin_7 PF13899.1 CBZ51751.1 - 8.9e-48 160.2 9.0 0.00013 21.9 0.0 9.4 9 0 0 9 9 9 9 Thioredoxin-like Thioredoxin_2 PF13098.1 CBZ51751.1 - 4.6e-39 133.0 22.8 0.0014 18.8 0.0 13.7 9 8 0 9 9 9 9 Thioredoxin-like domain Thioredoxin_8 PF13905.1 CBZ51751.1 - 7.3e-26 90.1 5.9 0.64 10.1 0.0 10.7 10 0 0 10 10 10 6 Thioredoxin-like Thioredoxin_9 PF14595.1 CBZ51751.1 - 1.7e-12 46.9 6.7 10 5.7 0.0 9.6 10 0 0 10 10 10 0 Thioredoxin NMD3 PF04981.8 CBZ51751.1 - 2.7e-08 33.2 0.0 6.4 5.8 0.0 5.7 5 0 0 5 5 5 4 NMD3 family DNA_alkylation PF08713.6 CBZ51751.1 - 4.5e-07 29.5 1.9 51 3.2 0.0 7.0 7 0 0 7 7 7 0 DNA alkylation repair enzyme DUF4291 PF14124.1 CBZ51751.1 - 0.0002 21.0 8.3 68 3.0 0.0 6.9 7 0 0 7 7 7 0 Domain of unknown function (DUF4291) Helicase_C_3 PF13625.1 CBZ51751.1 - 0.00096 18.9 0.0 95 2.7 0.0 5.7 5 0 0 5 5 5 0 Helicase conserved C-terminal domain DUF3741 PF12552.3 CBZ51751.1 - 0.0015 18.1 1.8 27 4.5 0.0 4.6 4 0 0 4 4 4 0 Protein of unknown function (DUF3741) Mu-like_Com PF10122.4 CBZ51751.1 - 0.0021 17.0 22.3 52 2.9 0.0 9.0 9 0 0 9 9 9 0 Mu-like prophage protein Com TOBE_3 PF12857.2 CBZ51751.1 - 0.026 14.3 14.7 1.2e+02 2.6 0.0 7.2 7 0 0 7 7 7 0 TOBE-like domain Glyco_trans_1_2 PF13524.1 CBZ51751.1 - 0.03 14.5 0.0 0.074 13.3 0.0 1.6 1 0 0 1 1 1 0 Glycosyl transferases group 1 DUF764 PF05561.6 CBZ51751.1 - 0.16 11.4 1.0 3.2e+02 0.6 0.0 5.5 7 0 0 7 7 7 0 Borrelia burgdorferi protein of unknown function (DUF764) HrcA PF01628.16 CBZ51751.1 - 0.28 10.7 0.0 1.6e+02 1.6 0.0 4.8 7 0 0 7 7 7 0 HrcA protein C terminal domain TSP_3 PF02412.13 CBZ51751.1 - 3.4 7.2 11.1 3.3e+02 0.8 0.0 6.4 7 0 0 7 7 7 0 Thrombospondin type 3 repeat SNase PF00565.12 CBZ51752.1 - 6.6e-56 187.1 0.6 3.3e-15 56.2 0.0 6.0 5 1 0 5 5 5 5 Staphylococcal nuclease homologue TUDOR PF00567.19 CBZ51752.1 - 6.6e-23 80.8 0.0 4.7e-22 78.1 0.0 2.4 2 0 0 2 2 2 1 Tudor domain EF-hand_7 PF13499.1 CBZ51753.1 - 3e-14 52.8 0.1 5.1e-11 42.5 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 CBZ51753.1 - 7.8e-09 35.0 0.3 2.1e-05 24.0 0.0 3.0 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.27 CBZ51753.1 - 9.8e-09 33.9 0.1 0.0078 15.4 0.0 3.4 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.1 CBZ51753.1 - 5.8e-08 31.9 1.2 0.0021 17.8 0.0 3.4 3 0 0 3 3 3 2 EF-hand domain PepSY_2 PF13670.1 CBZ51753.1 - 0.00029 20.6 0.1 0.00063 19.5 0.1 1.5 1 0 0 1 1 1 1 Peptidase propeptide and YPEB domain EF-hand_5 PF13202.1 CBZ51753.1 - 0.0086 15.3 7.4 0.97 8.8 0.1 3.7 3 1 0 3 3 3 2 EF hand OB_RNB PF08206.6 CBZ51753.1 - 0.15 11.5 0.0 0.32 10.5 0.0 1.4 1 0 0 1 1 1 0 Ribonuclease B OB domain Glutaredoxin PF00462.19 CBZ51754.1 - 2e-15 56.5 0.1 7.2e-15 54.7 0.0 1.9 2 0 0 2 2 2 1 Glutaredoxin Thioredoxin PF00085.15 CBZ51754.1 - 5.7e-06 25.9 0.1 1.7e-05 24.4 0.0 1.8 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_2 PF13098.1 CBZ51754.1 - 0.00093 19.3 0.0 0.023 14.9 0.0 2.3 1 1 1 2 2 2 1 Thioredoxin-like domain HyaE PF07449.6 CBZ51754.1 - 0.0029 17.4 0.1 0.093 12.6 0.0 2.6 1 1 1 2 2 2 1 Hydrogenase-1 expression protein HyaE TctA PF01970.11 CBZ51755.1 - 0.61 8.4 0.5 0.98 7.7 0.3 1.3 1 0 0 1 1 1 0 Tripartite tricarboxylate transporter TctA family Otopetrin PF03189.8 CBZ51755.1 - 3.8 6.3 3.0 7.5 5.4 2.1 1.5 1 0 0 1 1 1 0 Otopetrin EMP24_GP25L PF01105.19 CBZ51756.1 - 5.8e-38 130.4 0.1 7e-38 130.1 0.1 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF912 PF06024.7 CBZ51756.1 - 0.018 15.0 0.1 0.073 13.1 0.1 1.8 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Matrilin_ccoil PF10393.4 CBZ51756.1 - 0.11 11.8 0.6 0.24 10.8 0.4 1.5 1 0 0 1 1 1 0 Trimeric coiled-coil oligomerisation domain of matrilin Rep_fac-A_3 PF08661.6 CBZ51757.1 - 1.4e-07 31.4 0.0 1.6e-07 31.1 0.0 1.0 1 0 0 1 1 1 1 Replication factor A protein 3 HK PF02110.10 CBZ51757.1 - 0.11 11.6 0.0 0.13 11.3 0.0 1.1 1 0 0 1 1 1 0 Hydroxyethylthiazole kinase family HXXEE PF13787.1 CBZ51758.1 - 1.8e-12 47.6 0.4 1.8e-12 47.6 0.3 2.4 2 1 1 3 3 3 1 Protein of unknown function with HXXEE motif Form-deh_trans PF09163.6 CBZ51758.1 - 4 6.9 7.4 0.38 10.2 1.3 2.2 2 0 0 2 2 2 0 Formate dehydrogenase N, transmembrane RPN7 PF10602.4 CBZ51763.1 - 1.8e-53 180.5 0.9 2.7e-53 179.9 0.6 1.3 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.22 CBZ51763.1 - 1.3e-12 47.9 0.1 1.3e-11 44.7 0.0 2.5 3 0 0 3 3 3 1 PCI domain TPR_14 PF13428.1 CBZ51763.1 - 0.00042 20.7 0.1 1.3 9.9 0.0 3.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 CBZ51763.1 - 0.035 14.0 1.0 1.2 9.2 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.1 CBZ51763.1 - 0.036 13.8 0.1 0.88 9.5 0.1 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat RNA_pol_A_bac PF01000.21 CBZ51764.1 - 8.2e-25 87.1 0.0 1.8e-24 86.0 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 CBZ51764.1 - 1.6e-17 62.3 0.0 2.1e-17 61.9 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain KdgT PF03812.8 CBZ51764.1 - 0.017 14.2 0.1 0.027 13.6 0.0 1.2 1 0 0 1 1 1 0 2-keto-3-deoxygluconate permease Apo-VLDL-II PF05418.6 CBZ51764.1 - 0.18 12.0 0.0 0.45 10.7 0.0 1.6 1 0 0 1 1 1 0 Apovitellenin I (Apo-VLDL-II) Abhydrolase_3 PF07859.8 CBZ51765.1 - 9.9e-37 126.5 0.0 1.5e-36 125.9 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 CBZ51765.1 - 0.00091 18.0 0.1 0.0018 17.1 0.0 1.3 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_5 PF12695.2 CBZ51765.1 - 0.0011 18.6 0.0 0.0022 17.7 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 CBZ51765.1 - 0.0091 15.2 0.1 0.02 14.0 0.0 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family DUF2424 PF10340.4 CBZ51765.1 - 0.04 12.5 0.0 0.058 12.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2424) EGF PF00008.22 CBZ51766.1 - 0.019 14.9 8.1 0.019 14.9 5.6 5.9 5 1 0 5 5 5 0 EGF-like domain cEGF PF12662.2 CBZ51766.1 - 0.03 13.9 1.8 0.03 13.9 1.3 4.9 4 0 0 4 4 4 0 Complement Clr-like EGF-like FXa_inhibition PF14670.1 CBZ51766.1 - 0.23 11.6 48.8 1.4 9.1 3.7 5.2 3 2 2 5 5 5 0 Coagulation Factor Xa inhibitory site hEGF PF12661.2 CBZ51766.1 - 4.8 7.4 17.4 0.18 11.9 0.5 4.8 4 0 0 4 4 4 0 Human growth factor-like EGF cEGF PF12662.2 CBZ51767.1 - 0.0048 16.5 27.2 0.02 14.5 0.9 5.4 4 0 0 4 4 4 3 Complement Clr-like EGF-like EGF PF00008.22 CBZ51767.1 - 0.015 15.2 63.0 0.089 12.7 8.4 6.6 5 3 1 6 6 6 0 EGF-like domain FXa_inhibition PF14670.1 CBZ51767.1 - 0.018 15.1 5.5 0.018 15.1 3.8 5.0 4 0 0 4 4 4 0 Coagulation Factor Xa inhibitory site hEGF PF12661.2 CBZ51767.1 - 0.058 13.4 25.8 1.7 8.9 1.9 6.1 5 0 0 5 5 5 0 Human growth factor-like EGF EGF_3 PF12947.2 CBZ51767.1 - 0.22 11.5 54.0 0.36 10.8 2.4 5.3 4 1 0 4 4 4 0 EGF domain DBR1 PF05011.8 CBZ51768.1 - 5.3e-17 62.0 0.0 1.2e-16 60.8 0.0 1.6 2 0 0 2 2 2 1 Lariat debranching enzyme, C-terminal domain Metallophos PF00149.23 CBZ51768.1 - 2.6e-15 56.3 0.1 3.9e-15 55.7 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 CBZ51768.1 - 9.2e-06 25.5 0.0 1.7e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos_3 PF14582.1 CBZ51768.1 - 0.012 14.8 0.0 0.068 12.3 0.0 2.1 1 1 0 1 1 1 0 Metallophosphoesterase, calcineurin superfamily Bystin PF05291.6 CBZ51769.1 - 1.5e-114 381.9 0.0 2.1e-114 381.5 0.0 1.1 1 0 0 1 1 1 1 Bystin Phage_holin_5 PF06946.6 CBZ51769.1 - 0.084 13.0 0.2 0.23 11.6 0.1 1.7 1 0 0 1 1 1 0 Phage holin Ribosomal_L36e PF01158.13 CBZ51770.1 - 4.3e-36 122.8 4.5 4.9e-36 122.6 3.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e CLTH PF10607.4 CBZ51770.1 - 0.073 12.7 0.0 0.084 12.5 0.0 1.1 1 0 0 1 1 1 0 CTLH/CRA C-terminal to LisH motif domain Syja_N PF02383.13 CBZ51776.1 - 5.5e-64 215.9 0.0 1.1e-55 188.6 0.0 3.2 3 0 0 3 3 3 3 SacI homology domain Exo_endo_phos PF03372.18 CBZ51776.1 - 2.4e-18 67.0 0.0 7.9e-18 65.2 0.0 1.9 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family SAG PF04092.8 CBZ51780.1 - 5.5e-06 26.7 0.0 7.1e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 SRS domain AlaDh_PNT_C PF01262.16 CBZ51780.1 - 0.095 12.2 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain RRM_6 PF14259.1 CBZ51781.1 - 0.14 12.1 0.0 0.28 11.1 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRN3 PF05327.6 CBZ51782.1 - 3.8e-58 196.9 3.5 8.2e-58 195.8 0.0 3.4 2 1 0 2 2 2 1 RNA polymerase I specific transcription initiation factor RRN3 DUF3223 PF11523.3 CBZ51782.1 - 1.1e-07 32.0 0.2 3.1e-06 27.3 0.0 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3223) BetaGal_dom3 PF13363.1 CBZ51783.1 - 0.1 12.0 0.0 0.22 10.9 0.0 1.4 1 0 0 1 1 1 0 Beta-galactosidase, domain 3 Glyco_hydro_77 PF02446.12 CBZ51784.1 - 0.22 10.0 0.0 0.34 9.4 0.0 1.2 1 0 0 1 1 1 0 4-alpha-glucanotransferase Epimerase PF01370.16 CBZ51786.1 - 7.1e-65 218.7 0.0 8.8e-65 218.4 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 CBZ51786.1 - 5.2e-12 45.2 0.0 7.2e-12 44.7 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Epimerase_Csub PF13950.1 CBZ51786.1 - 0.04 13.8 0.0 0.085 12.8 0.0 1.5 1 0 0 1 1 1 0 UDP-glucose 4-epimerase C-term subunit FA_desaturase PF00487.19 CBZ51787.1 - 2.2e-11 43.7 19.3 2.2e-11 43.7 13.3 6.2 3 2 3 6 6 6 1 Fatty acid desaturase EF-hand_7 PF13499.1 CBZ51787.1 - 8e-06 25.9 0.3 0.02 15.0 0.1 2.6 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 CBZ51787.1 - 5.8e-05 22.6 0.4 0.15 11.9 0.0 3.4 2 1 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.27 CBZ51787.1 - 0.0029 16.7 0.1 0.45 9.9 0.0 3.2 3 0 0 3 3 3 1 EF hand DUF639 PF04842.7 CBZ51787.1 - 0.71 7.9 0.0 1.1 7.2 0.0 1.2 1 0 0 1 1 1 0 Plant protein of unknown function (DUF639) MCM PF00493.18 CBZ51788.1 - 4.4 6.0 0.2 9 4.9 0.0 1.5 2 0 0 2 2 2 0 MCM2/3/5 family Matrix PF00661.16 CBZ51788.1 - 8.2 4.6 0.0 13 3.9 0.0 1.2 1 0 0 1 1 1 0 Viral matrix protein Ion_trans_2 PF07885.11 CBZ51790.1 - 6e-11 41.9 3.9 1.6e-10 40.5 2.7 1.7 1 0 0 1 1 1 1 Ion channel BK_channel_a PF03493.13 CBZ51790.1 - 1.3e-07 31.4 0.0 2.6e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 Calcium-activated BK potassium channel alpha subunit ABC_membrane PF00664.18 CBZ51791.1 - 2.1e-92 309.4 16.8 1e-47 162.8 3.0 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 CBZ51791.1 - 1e-66 223.4 0.1 4.7e-33 114.3 0.0 3.7 3 1 0 3 3 3 2 ABC transporter SMC_N PF02463.14 CBZ51791.1 - 3.9e-16 58.9 1.8 4.2e-07 29.4 0.7 4.2 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 CBZ51791.1 - 4.4e-10 39.9 0.0 0.033 14.1 0.0 4.3 3 1 0 3 3 3 2 AAA domain AAA_17 PF13207.1 CBZ51791.1 - 8.7e-10 39.4 0.0 0.0019 19.0 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 CBZ51791.1 - 3.5e-09 36.0 0.8 0.00052 19.4 0.0 2.9 3 0 0 3 3 2 2 P-loop containing region of AAA domain AAA_16 PF13191.1 CBZ51791.1 - 1.4e-08 34.9 2.4 0.001 19.1 0.1 3.2 2 2 0 2 2 2 2 AAA ATPase domain DUF258 PF03193.11 CBZ51791.1 - 1.5e-08 34.0 0.0 0.0058 15.8 0.0 2.7 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_22 PF13401.1 CBZ51791.1 - 6.8e-08 32.7 1.4 0.033 14.3 0.1 4.4 3 1 0 3 3 3 2 AAA domain ABC_ATPase PF09818.4 CBZ51791.1 - 1.3e-06 27.2 2.3 0.038 12.5 0.1 3.3 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_18 PF13238.1 CBZ51791.1 - 1.6e-06 28.4 0.0 0.039 14.2 0.0 3.0 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 CBZ51791.1 - 9.8e-06 25.0 0.1 0.87 8.9 0.0 4.0 4 0 0 4 4 4 2 AAA domain AAA_28 PF13521.1 CBZ51791.1 - 2.7e-05 24.1 0.0 0.26 11.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.9 CBZ51791.1 - 3.8e-05 23.4 0.3 0.23 11.1 0.0 3.2 3 0 0 3 3 2 2 AAA domain (dynein-related subfamily) G-alpha PF00503.15 CBZ51791.1 - 3.9e-05 22.5 0.0 0.0061 15.2 0.0 2.1 2 0 0 2 2 2 1 G-protein alpha subunit SbcCD_C PF13558.1 CBZ51791.1 - 5.7e-05 22.9 7.5 0.046 13.6 0.3 5.1 4 2 0 4 4 3 1 Putative exonuclease SbcCD, C subunit AAA PF00004.24 CBZ51791.1 - 6.7e-05 23.0 1.8 0.085 13.0 0.0 4.2 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 CBZ51791.1 - 0.00036 20.4 0.0 0.99 9.2 0.0 2.8 2 0 0 2 2 2 2 AAA domain APS_kinase PF01583.15 CBZ51791.1 - 0.0004 20.0 0.0 1.2 8.7 0.0 2.7 2 0 0 2 2 2 2 Adenylylsulphate kinase DUF87 PF01935.12 CBZ51791.1 - 0.00084 19.2 0.2 0.16 11.7 0.0 2.7 2 0 0 2 2 2 1 Domain of unknown function DUF87 FtsK_SpoIIIE PF01580.13 CBZ51791.1 - 0.0011 18.5 0.1 2 7.8 0.1 2.6 2 0 0 2 2 2 2 FtsK/SpoIIIE family ATP-synt_ab PF00006.20 CBZ51791.1 - 0.0016 17.9 0.0 2 7.8 0.0 2.8 3 0 0 3 3 2 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_30 PF13604.1 CBZ51791.1 - 0.0017 17.9 10.4 0.42 10.1 0.0 4.8 5 1 0 5 5 4 2 AAA domain MobB PF03205.9 CBZ51791.1 - 0.0019 17.8 0.2 0.73 9.5 0.0 2.9 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B PRK PF00485.13 CBZ51791.1 - 0.0022 17.5 0.1 0.89 9.0 0.0 2.4 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family DUF815 PF05673.8 CBZ51791.1 - 0.0024 16.8 0.0 1.7 7.4 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF815) NACHT PF05729.7 CBZ51791.1 - 0.0033 17.1 3.6 0.87 9.2 0.0 3.3 4 0 0 4 4 4 1 NACHT domain UPF0079 PF02367.12 CBZ51791.1 - 0.0034 17.0 0.5 3.8 7.1 0.0 3.2 3 0 0 3 3 3 0 Uncharacterised P-loop hydrolase UPF0079 MMR_HSR1 PF01926.18 CBZ51791.1 - 0.0042 17.0 0.0 2.7 7.9 0.0 2.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_14 PF13173.1 CBZ51791.1 - 0.0042 16.9 0.2 9.1 6.1 0.0 3.5 4 0 0 4 4 3 0 AAA domain AAA_10 PF12846.2 CBZ51791.1 - 0.0056 16.1 0.8 1.6 8.0 0.2 3.5 3 1 1 4 4 4 1 AAA-like domain PduV-EutP PF10662.4 CBZ51791.1 - 0.0076 15.7 0.2 3.7 7.0 0.0 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Miro PF08477.8 CBZ51791.1 - 0.0077 16.7 0.1 2.1 8.8 0.0 2.8 2 0 0 2 2 2 1 Miro-like protein RNA_helicase PF00910.17 CBZ51791.1 - 0.011 15.9 0.0 4.9 7.3 0.0 2.6 2 0 0 2 2 2 0 RNA helicase CPT PF07931.7 CBZ51791.1 - 0.011 15.3 0.1 0.26 10.8 0.0 2.5 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein Sigma54_activ_2 PF14532.1 CBZ51791.1 - 0.013 15.5 0.0 8.9 6.3 0.0 3.3 3 0 0 3 3 3 0 Sigma-54 interaction domain NB-ARC PF00931.17 CBZ51791.1 - 0.019 13.8 0.3 5.9 5.6 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain Zeta_toxin PF06414.7 CBZ51791.1 - 0.037 13.1 0.1 3.7 6.5 0.0 2.6 2 0 0 2 2 2 0 Zeta toxin Rad17 PF03215.10 CBZ51791.1 - 0.041 12.5 0.0 0.87 8.1 0.0 2.1 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein TrkA_N PF02254.13 CBZ51791.1 - 0.077 13.0 3.0 0.36 10.8 0.0 3.1 3 0 0 3 3 3 0 TrkA-N domain AAA_23 PF13476.1 CBZ51791.1 - 0.088 13.1 0.0 11 6.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.12 CBZ51791.1 - 0.1 12.1 0.0 6.3 6.2 0.0 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein KAP_NTPase PF07693.9 CBZ51791.1 - 0.16 10.9 0.0 9.2 5.1 0.0 2.4 2 0 0 2 2 2 0 KAP family P-loop domain Mito_carr PF00153.22 CBZ51793.1 - 9.4e-57 188.7 2.1 3.2e-25 87.6 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Ribosomal_L23eN PF03939.8 CBZ51794.1 - 0.023 14.7 2.3 0.023 14.7 1.6 2.3 2 2 0 2 2 2 0 Ribosomal protein L23, N-terminal domain HOOK PF05622.7 CBZ51794.1 - 0.085 10.6 0.3 0.11 10.3 0.2 1.0 1 0 0 1 1 1 0 HOOK protein SAG PF04092.8 CBZ51795.1 - 9.2e-22 77.7 22.8 3.3e-12 46.8 4.9 2.2 2 0 0 2 2 2 2 SRS domain Ribosomal_S7e PF01251.13 CBZ51796.1 - 3.5e-66 222.3 9.7 4e-66 222.1 6.7 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e LRR_4 PF12799.2 CBZ51797.1 - 7.3e-13 47.8 25.6 2.2e-05 23.9 1.5 3.6 1 1 4 5 5 5 5 Leucine Rich repeats (2 copies) LRR_9 PF14580.1 CBZ51797.1 - 1.7e-09 37.5 2.8 1.2e-08 34.7 2.0 2.0 1 1 0 1 1 1 1 Leucine-rich repeat LRR_8 PF13855.1 CBZ51797.1 - 3.6e-07 29.8 8.5 1.1e-05 25.1 4.5 2.9 3 0 0 3 3 3 1 Leucine rich repeat PIH1 PF08190.7 CBZ51797.1 - 0.0013 18.2 4.2 0.0013 18.2 2.9 1.6 2 0 0 2 2 2 1 pre-RNA processing PIH1/Nop17 LRR_6 PF13516.1 CBZ51797.1 - 0.23 11.6 9.6 15 6.0 0.1 4.7 3 1 1 4 4 4 0 Leucine Rich repeat LRR_7 PF13504.1 CBZ51797.1 - 1.9 9.0 5.0 1e+02 3.8 0.0 4.5 3 1 1 4 4 4 0 Leucine rich repeat LRR_1 PF00560.28 CBZ51797.1 - 3.5 8.0 10.7 1.4e+02 3.1 0.6 4.5 2 1 0 2 2 2 0 Leucine Rich Repeat Pkinase_Tyr PF07714.12 CBZ51798.1 - 1.2e-48 165.5 0.0 8.5e-29 100.4 0.0 2.9 3 0 0 3 3 3 2 Protein tyrosine kinase Pkinase PF00069.20 CBZ51798.1 - 1.3e-47 162.1 0.0 2.2e-45 154.8 0.0 2.9 2 1 0 2 2 2 1 Protein kinase domain SAM_2 PF07647.12 CBZ51798.1 - 7.7e-05 22.4 0.0 0.00014 21.6 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) MORN PF02493.15 CBZ51798.1 - 0.00022 20.7 24.3 0.002 17.7 0.0 4.9 5 0 0 5 5 5 3 MORN repeat SAM_PNT PF02198.11 CBZ51798.1 - 0.055 13.2 0.0 0.14 11.9 0.0 1.6 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain SAM_1 PF00536.25 CBZ51798.1 - 0.081 13.1 0.0 0.15 12.2 0.0 1.3 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) DAGK_acc PF00609.14 CBZ51799.1 - 1.2e-39 136.0 0.0 2.6e-23 82.9 0.0 2.3 2 0 0 2 2 2 2 Diacylglycerol kinase accessory domain DAGK_cat PF00781.19 CBZ51799.1 - 1.1e-17 63.7 0.0 5.6e-11 41.9 0.0 2.4 2 0 0 2 2 2 2 Diacylglycerol kinase catalytic domain C1_1 PF00130.17 CBZ51799.1 - 8.1e-13 47.8 19.0 6e-08 32.2 1.9 3.8 5 0 0 5 5 5 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Histone PF00125.19 CBZ51800.1 - 2.6e-14 53.0 0.1 3.1e-14 52.8 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 CBZ51800.1 - 0.00015 21.9 0.0 0.00022 21.3 0.0 1.4 1 1 0 1 1 1 1 Kinetochore component CENP-S TAF PF02969.12 CBZ51800.1 - 0.00034 20.4 0.0 0.00044 20.1 0.0 1.2 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.18 CBZ51800.1 - 0.00046 20.1 0.0 0.00067 19.6 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T PF15511.1 CBZ51800.1 - 0.0028 16.9 0.0 0.003 16.8 0.0 1.0 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T Bromo_TP PF07524.8 CBZ51800.1 - 0.013 15.2 0.0 0.015 15.0 0.0 1.2 1 0 0 1 1 1 0 Bromodomain associated TFIID-31kDa PF02291.10 CBZ51800.1 - 0.054 13.2 0.0 0.057 13.1 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Rib_5-P_isom_A PF06026.9 CBZ51805.1 - 1.5e-49 167.6 0.1 3.4e-48 163.2 0.1 2.0 1 1 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) DeoRC PF00455.17 CBZ51805.1 - 0.00024 20.7 0.0 0.047 13.3 0.0 2.3 2 0 0 2 2 2 2 DeoR C terminal sensor domain Sugar-bind PF04198.8 CBZ51805.1 - 0.1 11.4 0.0 0.21 10.4 0.0 1.5 1 0 0 1 1 1 0 Putative sugar-binding domain BolA PF01722.13 CBZ51806.1 - 2.5e-23 81.8 0.3 3.4e-23 81.3 0.2 1.2 1 0 0 1 1 1 1 BolA-like protein SMN PF06003.7 CBZ51806.1 - 0.69 8.9 6.0 0.98 8.4 4.2 1.1 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) Ribosomal_L37e PF01907.14 CBZ51807.1 - 1e-24 86.0 13.9 2e-24 85.1 9.6 1.5 1 0 0 1 1 1 1 Ribosomal protein L37e SelR PF01641.13 CBZ51807.1 - 0.0021 17.7 0.3 0.0027 17.4 0.2 1.2 1 0 0 1 1 1 1 SelR domain DZR PF12773.2 CBZ51807.1 - 0.0026 17.5 1.7 0.0049 16.6 1.2 1.5 1 0 0 1 1 1 1 Double zinc ribbon zf-RING_5 PF14634.1 CBZ51807.1 - 0.1 12.3 2.5 0.17 11.6 1.7 1.4 1 0 0 1 1 1 0 zinc-RING finger domain GTP1_OBG PF01018.17 CBZ51808.1 - 2.1e-21 76.2 30.4 8.9e-14 51.4 0.5 5.0 5 1 0 5 5 5 3 GTP1/OBG DUF1967 PF09269.6 CBZ51808.1 - 1.4e-06 27.8 0.0 4.4e-06 26.2 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF1967) PduV-EutP PF10662.4 CBZ51808.1 - 0.00065 19.2 0.0 0.2 11.1 0.0 2.2 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation cobW PF02492.14 CBZ51808.1 - 0.0057 16.1 0.0 1.3 8.4 0.0 2.4 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain GTP_EFTU PF00009.22 CBZ51808.1 - 0.012 15.0 0.0 0.029 13.8 0.0 1.6 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain ATP_bind_1 PF03029.12 CBZ51808.1 - 0.037 13.5 0.1 6.5 6.2 0.1 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Miro PF08477.8 CBZ51808.1 - 0.14 12.6 0.0 0.32 11.5 0.0 1.5 1 0 0 1 1 1 0 Miro-like protein RAP PF08373.5 CBZ51809.1 - 2e-09 37.0 0.0 3.3e-09 36.3 0.0 1.4 1 0 0 1 1 1 1 RAP domain FAST_1 PF06743.10 CBZ51809.1 - 0.044 13.4 0.0 0.16 11.6 0.0 2.0 1 0 0 1 1 1 0 FAST kinase-like protein, subdomain 1 Pkinase PF00069.20 CBZ51811.1 - 7.6e-14 51.4 0.0 1.1e-05 24.7 0.0 3.7 4 0 0 4 4 4 2 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ51811.1 - 0.0017 17.5 0.0 0.071 12.1 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase zf-RING_4 PF14570.1 CBZ51813.1 - 1.2e-19 69.6 10.7 1.9e-19 68.9 7.4 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.1 CBZ51813.1 - 4e-05 23.2 6.8 6.4e-05 22.5 4.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RRM_5 PF13893.1 CBZ51813.1 - 5.3e-05 22.9 0.0 9.3e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CBZ51813.1 - 0.0011 18.5 0.0 0.0022 17.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-RING_2 PF13639.1 CBZ51813.1 - 0.003 17.3 11.0 0.0049 16.6 7.6 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 CBZ51813.1 - 0.016 14.8 8.9 0.026 14.1 6.2 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CBZ51813.1 - 0.041 13.9 10.2 0.068 13.2 7.0 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-UDP PF14569.1 CBZ51813.1 - 0.075 12.7 3.6 0.23 11.2 2.5 1.8 1 0 0 1 1 1 0 Zinc-binding RING-finger RRM_6 PF14259.1 CBZ51813.1 - 0.089 12.7 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Baculo_IE-1 PF05290.6 CBZ51813.1 - 2.4 7.8 1.9 3.8 7.2 1.3 1.2 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-RING_5 PF14634.1 CBZ51813.1 - 6.7 6.5 8.3 11 5.7 5.8 1.4 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_4 PF15227.1 CBZ51813.1 - 8.3 6.3 8.6 19 5.2 6.0 1.6 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING Pkinase PF00069.20 CBZ51814.1 - 7.9e-42 143.1 0.0 1.1e-40 139.4 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ51814.1 - 6.6e-15 54.8 0.0 3.8e-08 32.7 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.9 CBZ51814.1 - 0.023 13.7 0.0 0.054 12.5 0.0 1.5 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 CBZ51814.1 - 0.051 12.5 0.0 0.31 9.9 0.0 1.9 2 0 0 2 2 2 0 Kinase-like Seadorna_VP7 PF07387.6 CBZ51814.1 - 3 6.6 0.1 4.4 6.0 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 Mlo PF03094.10 CBZ51815.1 - 0.00034 18.8 19.4 0.0019 16.4 2.1 4.0 3 1 0 4 4 4 3 Mlo family DUF4131 PF13567.1 CBZ51815.1 - 9 5.6 10.6 2.5 7.4 2.0 3.2 4 0 0 4 4 4 0 Domain of unknown function (DUF4131) Pkinase PF00069.20 CBZ51816.1 - 8.9e-49 165.9 0.0 9.9e-32 110.0 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ51816.1 - 1.6e-30 106.0 0.0 6.6e-24 84.3 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 CBZ51816.1 - 6.1e-05 22.1 0.0 0.00017 20.6 0.0 1.6 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.17 CBZ51816.1 - 0.29 10.4 0.0 0.56 9.5 0.0 1.4 1 0 0 1 1 1 0 RIO1 family DUF1042 PF06294.6 CBZ51817.1 - 8.2e-11 41.7 5.5 2.1e-10 40.4 0.0 2.4 2 0 0 2 2 2 1 Domain of Unknown Function (DUF1042) AAA_17 PF13207.1 CBZ51817.1 - 4.6e-05 24.2 4.4 0.0001 23.0 0.0 3.5 3 1 0 3 3 3 1 AAA domain AAA_18 PF13238.1 CBZ51817.1 - 0.00035 20.8 0.0 0.018 15.3 0.0 2.9 2 0 0 2 2 2 1 AAA domain KTI12 PF08433.5 CBZ51817.1 - 0.0071 15.5 0.0 0.019 14.2 0.0 1.6 1 0 0 1 1 1 1 Chromatin associated protein KTI12 ADK PF00406.17 CBZ51817.1 - 0.014 15.2 0.0 0.94 9.3 0.0 2.8 3 0 0 3 3 3 0 Adenylate kinase RNB PF00773.14 CBZ51818.1 - 2.3e-69 234.1 0.0 7.9e-36 123.9 0.0 2.2 2 0 0 2 2 2 2 RNB domain DUF2950 PF11453.3 CBZ51818.1 - 0.13 11.2 0.0 0.22 10.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2950) E1_dh PF00676.15 CBZ51819.1 - 8.9e-78 261.0 0.0 1.1e-77 260.6 0.0 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.1 CBZ51819.1 - 0.00029 19.8 0.0 0.00083 18.3 0.0 1.7 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase Transketolase_N PF00456.16 CBZ51819.1 - 0.0014 17.5 0.0 0.0026 16.6 0.0 1.3 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Proteasome PF00227.21 CBZ51820.1 - 1.5e-58 197.2 0.0 1.9e-58 196.8 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 CBZ51820.1 - 1.5e-14 52.9 0.4 2.6e-14 52.2 0.2 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature START PF01852.14 CBZ51821.1 - 0.00058 19.2 0.0 0.0011 18.2 0.0 1.6 1 1 0 1 1 1 1 START domain Methyltransf_20 PF12147.3 CBZ51822.1 - 0.06 12.2 0.0 0.097 11.5 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Aminotran_5 PF00266.14 CBZ51823.1 - 1.8e-39 135.5 0.0 2.1e-39 135.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.16 CBZ51823.1 - 0.00019 20.5 0.0 0.012 14.6 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 CBZ51823.1 - 0.0033 16.5 0.0 0.041 12.9 0.0 2.0 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family CDC50 PF03381.10 CBZ51824.1 - 4.3e-66 222.9 0.0 5.3e-66 222.6 0.0 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family Robl_LC7 PF03259.12 CBZ51825.1 - 8.2e-12 44.5 0.0 9.5e-12 44.3 0.0 1.1 1 0 0 1 1 1 1 Roadblock/LC7 domain Myosin_head PF00063.16 CBZ51826.1 - 1.5e-161 538.9 0.0 2.7e-161 538.0 0.0 1.3 1 1 0 1 1 1 1 Myosin head (motor domain) DUF258 PF03193.11 CBZ51826.1 - 0.036 13.2 0.0 0.12 11.5 0.0 1.9 1 1 0 1 1 1 0 Protein of unknown function, DUF258 AAA_22 PF13401.1 CBZ51826.1 - 0.049 13.7 0.0 0.18 11.9 0.0 2.1 1 0 0 1 1 1 0 AAA domain Ran_BP1 PF00638.13 CBZ51826.1 - 0.071 13.1 0.0 0.17 11.9 0.0 1.7 1 0 0 1 1 1 0 RanBP1 domain NACHT PF05729.7 CBZ51826.1 - 0.11 12.1 0.0 0.27 10.9 0.0 1.7 1 0 0 1 1 1 0 NACHT domain WD40 PF00400.27 CBZ51829.1 - 1.6e-23 81.6 9.5 3.2e-10 39.4 0.1 6.6 5 2 0 5 5 5 3 WD domain, G-beta repeat UTP15_C PF09384.5 CBZ51829.1 - 5.8e-21 74.7 1.7 9.6e-21 74.0 1.2 1.3 1 0 0 1 1 1 1 UTP15 C terminal Cwf_Cwc_15 PF04889.7 CBZ51829.1 - 0.089 12.4 5.7 0.17 11.6 3.9 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein FAM176 PF14851.1 CBZ51829.1 - 0.094 12.3 2.1 0.53 9.9 2.0 1.7 2 0 0 2 2 2 0 FAM176 family Cytochrom_D1 PF02239.11 CBZ51829.1 - 0.1 10.8 0.2 0.16 10.2 0.1 1.2 1 0 0 1 1 1 0 Cytochrome D1 heme domain Myc_N PF01056.13 CBZ51829.1 - 0.15 11.2 5.5 0.28 10.3 3.8 1.3 1 0 0 1 1 1 0 Myc amino-terminal region Sigma70_ner PF04546.8 CBZ51829.1 - 0.17 11.5 6.7 0.31 10.6 4.6 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region RXT2_N PF08595.6 CBZ51829.1 - 0.19 11.5 2.9 0.43 10.3 2.0 1.5 1 0 0 1 1 1 0 RXT2-like, N-terminal Nucleo_P87 PF07267.6 CBZ51829.1 - 0.38 9.3 3.0 0.57 8.7 2.1 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 PBP1_TM PF14812.1 CBZ51829.1 - 0.7 10.2 15.7 0.49 10.7 9.0 2.0 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Adeno_terminal PF02459.10 CBZ51829.1 - 1.8 6.6 5.8 3.2 5.8 4.0 1.3 1 0 0 1 1 1 0 Adenoviral DNA terminal protein Kinase-like PF14531.1 CBZ51830.1 - 4.8e-70 235.7 0.0 6.6e-70 235.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase PF00069.20 CBZ51830.1 - 1.1e-08 34.5 0.0 1.6e-08 34.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ51830.1 - 0.0027 16.8 0.0 0.0041 16.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase 5_nucleotid_C PF02872.13 CBZ51832.1 - 6.1e-33 114.0 0.0 1.3e-32 112.9 0.0 1.5 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.23 CBZ51832.1 - 8.7e-06 25.2 0.2 2.2e-05 23.9 0.1 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Tox-ODYAM1 PF15642.1 CBZ51832.1 - 0.053 12.1 0.0 0.12 11.0 0.0 1.5 2 0 0 2 2 2 0 Toxin in Odyssella and Amoebophilus SR-25 PF10500.4 CBZ51832.1 - 1.8 8.0 11.0 3.7 6.9 7.6 1.5 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein dCMP_cyt_deam_2 PF08211.6 CBZ51833.1 - 6.2e-19 68.2 0.2 4.3e-10 39.6 0.0 2.3 2 0 0 2 2 2 2 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_1 PF00383.17 CBZ51833.1 - 5.9e-18 64.4 11.9 5.3e-12 45.2 1.3 2.8 2 1 1 3 3 3 2 Cytidine and deoxycytidylate deaminase zinc-binding region LmjF365940-deam PF14421.1 CBZ51833.1 - 0.024 14.0 6.2 2.2 7.6 0.0 3.6 3 1 0 3 3 3 0 A distinct subfamily of CDD/CDA-like deaminases Med27 PF11571.3 CBZ51833.1 - 0.068 13.3 0.0 0.14 12.3 0.0 1.4 1 0 0 1 1 1 0 Mediator complex subunit 27 DUF2685 PF10886.3 CBZ51833.1 - 3.6 7.6 6.4 7.1 6.7 0.4 3.5 4 0 0 4 4 4 0 Protein of unknown function (DUF2685) Bot1p PF12298.3 CBZ51834.1 - 0.059 13.3 0.1 0.26 11.2 0.0 1.8 2 0 0 2 2 2 0 Eukaryotic mitochondrial regulator protein Rab5ip PF07019.7 CBZ51839.1 - 5.4e-09 36.0 9.6 6.6e-05 22.9 4.5 2.2 2 0 0 2 2 2 2 Rab5-interacting protein (Rab5ip) RCC1_2 PF13540.1 CBZ51840.1 - 2.5e-17 61.9 27.0 6.2e-05 22.4 2.2 6.5 6 0 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.13 CBZ51840.1 - 1.7e-13 50.5 15.6 0.018 15.2 1.5 8.9 8 1 0 8 8 8 5 Regulator of chromosome condensation (RCC1) repeat PMM PF03332.8 CBZ51841.1 - 1.5e-90 302.6 0.0 1.8e-90 302.3 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.7 CBZ51841.1 - 5.1e-11 42.6 0.0 3.4e-10 39.9 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.8 CBZ51841.1 - 4.1e-08 32.8 0.0 0.005 16.1 0.0 2.1 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase HAD_2 PF13419.1 CBZ51841.1 - 0.00078 19.7 0.1 0.052 13.7 0.0 2.3 1 1 1 2 2 2 1 Haloacid dehalogenase-like hydrolase HAD PF12710.2 CBZ51841.1 - 0.017 15.3 0.9 0.23 11.5 0.6 2.5 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 CBZ51841.1 - 0.052 13.9 0.0 0.072 13.4 0.0 1.3 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase KOW PF00467.24 CBZ51842.1 - 2.1e-05 24.0 0.9 4e-05 23.1 0.6 1.5 1 0 0 1 1 1 1 KOW motif MORN PF02493.15 CBZ51843.1 - 1.2e-12 46.7 20.0 5.2e-07 29.0 2.0 3.5 3 0 0 3 3 3 3 MORN repeat Fringe PF02434.11 CBZ51845.1 - 1e-21 77.3 1.7 4e-10 39.3 0.0 3.6 4 0 0 4 4 4 3 Fringe-like PIG-H PF10181.4 CBZ51845.1 - 9.4e-13 47.5 0.1 1.6e-12 46.8 0.1 1.4 1 0 0 1 1 1 1 GPI-GlcNAc transferase complex, PIG-H component Galactosyl_T PF01762.16 CBZ51845.1 - 0.016 14.8 0.0 0.85 9.1 0.0 2.3 2 0 0 2 2 2 0 Galactosyltransferase Ribosomal_L22e PF01776.12 CBZ51846.1 - 3.2e-43 146.2 1.4 4.7e-43 145.7 1.0 1.2 1 0 0 1 1 1 1 Ribosomal L22e protein family FERM_M PF00373.13 CBZ51846.1 - 0.066 13.3 0.1 0.1 12.7 0.1 1.5 1 1 0 1 1 1 0 FERM central domain IMCp PF12314.3 CBZ51847.1 - 2.6e-23 81.9 36.0 2.1e-21 75.8 20.0 2.3 2 0 0 2 2 2 2 Inner membrane complex protein Pescadillo_N PF06732.6 CBZ51850.1 - 8.7e-83 277.8 1.2 1.5e-82 276.9 0.8 1.3 1 0 0 1 1 1 1 Pescadillo N-terminus BRCT PF00533.21 CBZ51850.1 - 2e-07 31.0 0.0 3.6e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain Chorein_N PF12624.2 CBZ51851.1 - 3.6e-07 29.7 0.1 5.3e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 N-terminal region of Chorein, a TM vesicle-mediated sorter HlyD_2 PF12700.2 CBZ51851.1 - 0.041 13.0 0.0 0.055 12.6 0.0 1.1 1 0 0 1 1 1 0 HlyD family secretion protein 2-Hacid_dh_C PF02826.14 CBZ51853.1 - 1.1e-43 148.5 1.6 2.1e-43 147.5 0.3 2.0 1 1 1 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 CBZ51853.1 - 5.6e-33 113.2 1.1 7.6e-33 112.7 0.7 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain DSBA PF01323.15 CBZ51853.1 - 0.028 13.9 0.1 0.25 10.8 0.0 2.3 2 0 0 2 2 2 0 DSBA-like thioredoxin domain PHO4 PF01384.15 CBZ51856.1 - 4.2e-111 370.7 0.0 6.1e-111 370.1 0.0 1.2 1 0 0 1 1 1 1 Phosphate transporter family AJAP1_PANP_C PF15298.1 CBZ51856.1 - 0.1 12.4 0.0 5.4 6.8 0.0 2.3 2 0 0 2 2 2 0 AJAP1/PANP C-terminus Reo_sigmaC PF04582.7 CBZ51857.1 - 2 7.5 9.2 8.2 5.4 0.1 3.4 2 1 2 4 4 4 0 Reovirus sigma C capsid protein Tropomyosin PF00261.15 CBZ51858.1 - 0.027 13.5 6.2 0.033 13.2 2.7 1.9 1 1 1 2 2 2 0 Tropomyosin DUF2031 PF09592.5 CBZ51858.1 - 0.053 12.6 0.8 0.064 12.3 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2031) NPV_P10 PF05531.7 CBZ51858.1 - 0.077 13.2 1.3 0.69 10.1 0.0 2.7 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF1664 PF07889.7 CBZ51858.1 - 0.42 10.4 5.9 0.29 10.9 1.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) PEP-utilisers_N PF05524.8 CBZ51858.1 - 0.62 9.8 4.9 0.21 11.4 0.7 2.0 2 0 0 2 2 2 0 PEP-utilising enzyme, N-terminal Peptidase_S8 PF00082.17 CBZ51859.1 - 3.3e-29 101.9 0.1 1.8e-28 99.4 0.0 2.3 2 1 0 2 2 2 1 Subtilase family Macro PF01661.16 CBZ51860.1 - 1.6e-32 111.8 0.1 3.6e-32 110.7 0.0 1.6 1 0 0 1 1 1 1 Macro domain S1-P1_nuclease PF02265.11 CBZ51862.1 - 2.9e-19 69.6 0.5 1.2e-17 64.4 0.4 2.1 1 1 0 1 1 1 1 S1/P1 Nuclease Mu-like_Com PF10122.4 CBZ51863.1 - 3.9 6.5 13.7 0.31 10.1 0.5 3.6 1 1 2 3 3 3 0 Mu-like prophage protein Com eIF3_p135 PF12807.2 CBZ51867.1 - 1.6e-11 44.4 0.0 3.1e-11 43.4 0.0 1.4 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit 135 TPR_12 PF13424.1 CBZ51867.1 - 2e-06 27.6 1.2 0.00091 19.1 0.0 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat Apc3 PF12895.2 CBZ51867.1 - 0.011 15.8 0.1 0.045 13.9 0.0 2.1 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 CLU PF13236.1 CBZ51867.1 - 0.47 9.8 0.0 0.92 8.8 0.0 1.4 1 0 0 1 1 1 0 Clustered mitochondria Pkinase PF00069.20 CBZ51868.1 - 3.9e-52 176.9 0.0 1.1e-37 129.6 0.0 3.1 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ51868.1 - 2e-21 76.2 0.0 4.1e-19 68.6 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase EF-hand_1 PF00036.27 CBZ51868.1 - 2.2e-19 67.2 0.1 0.00011 21.2 0.0 4.6 4 0 0 4 4 4 4 EF hand EF-hand_5 PF13202.1 CBZ51868.1 - 2.5e-16 58.2 0.5 1.7e-05 23.9 0.0 4.6 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 CBZ51868.1 - 6.2e-15 55.0 0.2 1.4e-06 28.2 0.1 3.5 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.1 CBZ51868.1 - 2.8e-14 51.6 3.0 8.9e-05 22.0 0.0 4.9 5 0 0 5 5 5 4 EF-hand domain EF-hand_8 PF13833.1 CBZ51868.1 - 5.4e-12 45.1 0.5 0.32 10.6 0.0 4.4 4 0 0 4 4 4 4 EF-hand domain pair Kdo PF06293.9 CBZ51868.1 - 0.023 13.7 0.1 0.052 12.6 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family SPARC_Ca_bdg PF10591.4 CBZ51868.1 - 0.61 10.1 5.5 48 4.0 0.3 4.2 3 1 1 4 4 4 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 CBZ51868.1 - 1.3 8.8 0.3 36 4.1 0.0 3.0 3 0 0 3 3 3 0 Cytoskeletal-regulatory complex EF hand rRNA_processing PF08524.6 CBZ51869.1 - 2.6e-06 27.2 23.8 2.6e-06 27.2 16.5 3.8 3 2 1 4 4 4 2 rRNA processing Pkinase PF00069.20 CBZ51870.1 - 1.8e-34 119.0 0.0 1.6e-22 79.9 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ51870.1 - 6.8e-19 67.9 0.0 1e-11 44.4 0.0 2.3 2 1 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 CBZ51870.1 - 0.0054 15.7 0.0 0.19 10.6 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Seadorna_VP7 PF07387.6 CBZ51870.1 - 0.13 11.0 0.0 0.19 10.4 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 Glyoxalase_2 PF12681.2 CBZ51871.1 - 7.1e-05 23.3 0.1 0.086 13.4 0.0 3.9 4 1 0 4 4 4 2 Glyoxalase-like domain Glyoxalase PF00903.20 CBZ51871.1 - 0.013 15.4 0.0 0.2 11.6 0.0 2.9 1 1 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily PepSY_2 PF13670.1 CBZ51871.1 - 0.3 11.0 0.0 0.3 11.0 0.0 3.8 4 0 0 4 4 4 0 Peptidase propeptide and YPEB domain DUF2408 PF10303.4 CBZ51872.1 - 0.1 12.7 1.1 0.53 10.3 0.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) Pox_A_type_inc PF04508.7 CBZ51872.1 - 0.7 9.8 3.4 0.96 9.3 0.3 2.6 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat DUF1192 PF06698.6 CBZ51872.1 - 9 6.1 10.1 0.82 9.5 0.9 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1192) Maf PF02545.9 CBZ51873.1 - 1.3e-33 115.8 0.0 4.3e-33 114.0 0.0 1.7 1 1 0 1 1 1 1 Maf-like protein AP2 PF00847.15 CBZ51874.1 - 9.1e-15 54.5 11.2 1.8e-07 31.2 0.2 2.9 3 0 0 3 3 3 2 AP2 domain DUF3107 PF11305.3 CBZ51874.1 - 0.11 12.3 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3107) CPW_WPC PF09717.5 CBZ51876.1 - 1.7e-15 57.3 6.1 1e-12 48.4 0.3 2.2 2 0 0 2 2 2 2 Plasmodium falciparum domain of unknown function (CPW_WPC) DUF680 PF05079.7 CBZ51877.1 - 0.15 12.5 0.7 0.32 11.5 0.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF680) PITH PF06201.8 CBZ51878.1 - 1.2e-25 90.0 0.3 2.8e-25 88.8 0.0 1.7 2 0 0 2 2 2 1 PITH domain Oligomerisation PF02410.10 CBZ51880.1 - 9.5e-14 51.2 0.0 1.6e-13 50.5 0.0 1.3 1 0 0 1 1 1 1 Oligomerisation domain D5_N PF08706.6 CBZ51881.1 - 0.029 14.4 0.7 0.046 13.8 0.3 1.5 1 1 0 1 1 1 0 D5 N terminal like ZYG-11_interact PF05884.7 CBZ51881.1 - 0.14 11.2 0.5 0.27 10.2 0.1 1.6 2 0 0 2 2 2 0 Interactor of ZYG-11 Gp-FAR-1 PF05823.7 CBZ51881.1 - 0.16 11.8 4.4 0.16 11.9 1.5 2.0 2 0 0 2 2 2 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) PLRV_ORF5 PF01690.12 CBZ51881.1 - 4 6.4 7.4 5.2 6.1 5.1 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Enkurin PF13864.1 CBZ51881.1 - 9.6 6.4 17.0 6 7.1 4.2 2.7 2 1 0 2 2 2 0 Calmodulin-binding Dor1 PF04124.7 CBZ51882.1 - 2.5e-20 72.2 0.1 1.2e-17 63.4 0.1 2.1 1 1 0 1 1 1 1 Dor1-like family PPR PF01535.15 CBZ51882.1 - 0.1 12.6 0.0 0.52 10.4 0.0 2.3 2 0 0 2 2 2 0 PPR repeat COX17 PF05051.8 CBZ51883.1 - 4.7e-22 77.7 5.8 5.8e-22 77.4 4.0 1.2 1 0 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) MAPEG PF01124.13 CBZ51884.1 - 1.2e-19 70.2 1.2 1.7e-19 69.7 0.8 1.2 1 0 0 1 1 1 1 MAPEG family RNA_pol_Rpb5_N PF03871.9 CBZ51887.1 - 0.00037 20.8 0.0 0.00064 20.0 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain Mrr_cat PF04471.7 CBZ51887.1 - 0.00048 19.9 0.0 0.00083 19.1 0.0 1.4 1 0 0 1 1 1 1 Restriction endonuclease Cpn60_TCP1 PF00118.19 CBZ51888.1 - 6.7e-102 341.6 0.1 1.6e-101 340.3 0.0 1.5 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF1192 PF06698.6 CBZ51888.1 - 0.071 12.9 0.6 9.6 6.1 0.0 3.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1192) Pkinase PF00069.20 CBZ51891.1 - 2e-23 82.8 0.1 1.7e-15 56.9 0.2 2.0 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ51891.1 - 1.3e-15 57.1 0.0 4e-10 39.2 0.0 2.0 1 1 1 2 2 2 2 Protein tyrosine kinase APH PF01636.18 CBZ51891.1 - 0.0049 16.6 0.0 0.13 11.9 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 CBZ51891.1 - 0.024 13.7 0.2 0.56 9.2 0.0 2.1 1 1 1 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 CBZ51891.1 - 0.11 11.8 0.0 0.18 11.1 0.0 1.4 1 1 0 1 1 1 0 PhoP regulatory network protein YrbL Pox_ser-thr_kin PF05445.6 CBZ51891.1 - 0.12 11.1 0.1 0.16 10.7 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Pkinase PF00069.20 CBZ51892.1 - 4.6e-37 127.5 0.0 5.7e-37 127.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ51892.1 - 1.3e-15 57.2 0.0 1.6e-15 56.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CBZ51892.1 - 2.4e-05 24.2 0.0 0.0004 20.1 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 CBZ51892.1 - 0.0066 15.2 0.1 0.012 14.4 0.1 1.3 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase Coatomer_WDAD PF04053.9 CBZ51893.1 - 8.1e-86 288.5 0.0 6.2e-84 282.3 0.0 2.3 1 1 0 1 1 1 1 Coatomer WD associated region WD40 PF00400.27 CBZ51893.1 - 7.3e-58 190.5 10.8 5.8e-10 38.6 0.0 8.2 8 0 0 8 8 8 6 WD domain, G-beta repeat COPI_C PF06957.6 CBZ51893.1 - 1.6e-37 129.0 0.0 2.4e-37 128.4 0.0 1.1 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus Nucleoporin_N PF08801.6 CBZ51893.1 - 0.0001 21.2 0.3 0.061 12.0 0.0 3.2 2 1 1 3 3 3 1 Nup133 N terminal like ENTH PF01417.15 CBZ51893.1 - 0.054 13.3 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 ENTH domain Nup160 PF11715.3 CBZ51893.1 - 0.069 11.2 9.6 2.2 6.2 0.1 4.2 2 1 2 4 4 4 0 Nucleoporin Nup120/160 TPR_16 PF13432.1 CBZ51893.1 - 0.11 13.2 5.3 4.7 8.0 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF2361 PF10153.4 CBZ51894.1 - 3.4e-12 46.5 8.6 3.4e-12 46.5 6.0 2.2 3 0 0 3 3 3 1 Uncharacterised conserved protein (DUF2361) CorA PF01544.13 CBZ51894.1 - 0.49 9.3 5.2 0.67 8.9 3.6 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Fer2 PF00111.22 CBZ51895.1 - 2.2e-11 43.3 2.7 4.6e-11 42.2 1.8 1.6 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain S-AdoMet_synt_C PF02773.11 CBZ51896.1 - 6.1e-64 213.8 0.0 9.3e-64 213.2 0.0 1.3 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.11 CBZ51896.1 - 3.4e-49 165.7 0.0 7.1e-49 164.7 0.0 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.15 CBZ51896.1 - 3.6e-43 145.8 0.4 6.1e-43 145.1 0.2 1.4 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, N-terminal domain ubiquitin PF00240.18 CBZ51897.1 - 1e-08 34.4 0.0 2.3e-08 33.2 0.0 1.6 2 0 0 2 2 2 1 Ubiquitin family UBA PF00627.26 CBZ51897.1 - 5e-08 32.5 0.2 2.5e-07 30.3 0.0 2.2 2 0 0 2 2 2 1 UBA/TS-N domain UBA_4 PF14555.1 CBZ51897.1 - 0.002 17.6 0.0 0.0042 16.5 0.0 1.4 1 0 0 1 1 1 1 UBA-like domain RRM_1 PF00076.17 CBZ51898.1 - 1.3e-15 56.7 0.0 4.4e-15 55.0 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Surp PF01805.15 CBZ51898.1 - 1.2e-12 47.2 0.0 2.5e-12 46.2 0.0 1.5 1 0 0 1 1 1 1 Surp module RRM_5 PF13893.1 CBZ51898.1 - 1.5e-09 37.5 0.0 3e-09 36.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBZ51898.1 - 6.2e-08 32.5 0.0 1.3e-07 31.4 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) cwf21 PF08312.7 CBZ51898.1 - 1.1e-05 25.1 9.7 5.8e-05 22.8 6.7 2.3 1 0 0 1 1 1 1 cwf21 domain CTK3 PF12243.3 CBZ51898.1 - 8.6e-05 22.1 0.1 0.00023 20.8 0.0 1.6 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 MgtE PF01769.11 CBZ51899.1 - 0.00071 19.8 3.6 0.023 14.9 0.3 2.1 2 0 0 2 2 2 2 Divalent cation transporter Peptidase_M50 PF02163.17 CBZ51899.1 - 0.023 13.6 0.1 0.039 12.8 0.0 1.3 1 1 0 1 1 1 0 Peptidase family M50 SHD1 PF03983.7 CBZ51899.1 - 0.13 11.9 0.0 0.22 11.2 0.0 1.2 1 0 0 1 1 1 0 SLA1 homology domain 1, SHD1 DUF4131 PF13567.1 CBZ51899.1 - 8 5.8 9.1 0.76 9.1 1.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Sec1 PF00995.18 CBZ51900.1 - 6.6e-106 355.1 0.0 7.7e-106 354.9 0.0 1.0 1 0 0 1 1 1 1 Sec1 family Cyt-b5 PF00173.23 CBZ51901.1 - 9.4e-13 47.7 0.0 1.6e-12 47.0 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FA_hydroxylase PF04116.8 CBZ51901.1 - 1.7e-09 38.0 15.1 3.2e-09 37.1 10.5 1.4 1 0 0 1 1 1 1 Fatty acid hydroxylase superfamily Dpy19 PF10034.4 CBZ51902.1 - 0.036 12.2 0.2 0.039 12.1 0.1 1.0 1 0 0 1 1 1 0 Q-cell neuroblast polarisation Med12 PF09497.5 CBZ51902.1 - 0.12 12.3 0.2 0.34 10.9 0.0 1.8 2 1 0 2 2 2 0 Transcription mediator complex subunit Med12 Dynein_light PF01221.13 CBZ51903.1 - 1.8e-21 75.9 0.0 2.4e-21 75.5 0.0 1.2 1 0 0 1 1 1 1 Dynein light chain type 1 MORN PF02493.15 CBZ51904.1 - 5.8e-22 76.0 30.2 3.1e-05 23.4 0.8 6.6 7 0 0 7 7 7 5 MORN repeat DUF2304 PF10066.4 CBZ51905.1 - 0.52 10.1 5.4 1.9 8.3 3.7 2.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2304) Abhydrolase_6 PF12697.2 CBZ51906.1 - 5e-30 105.0 1.0 8.1e-30 104.3 0.7 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CBZ51906.1 - 3.7e-13 49.4 0.0 3.5e-12 46.2 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CBZ51906.1 - 4.8e-10 39.3 0.9 3.7e-08 33.2 0.2 2.7 2 1 0 2 2 2 1 alpha/beta hydrolase fold PGAP1 PF07819.8 CBZ51906.1 - 3e-06 27.0 0.1 5e-05 23.0 0.0 2.5 2 1 0 2 2 2 1 PGAP1-like protein Esterase PF00756.15 CBZ51906.1 - 4.4e-05 23.0 0.1 0.00011 21.7 0.0 1.7 1 1 0 1 1 1 1 Putative esterase Thioesterase PF00975.15 CBZ51906.1 - 0.0044 17.2 0.0 0.012 15.9 0.0 1.6 1 0 0 1 1 1 1 Thioesterase domain DUF2974 PF11187.3 CBZ51906.1 - 0.0089 15.4 0.0 0.016 14.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) DUF676 PF05057.9 CBZ51906.1 - 0.03 13.6 0.0 2.4 7.3 0.0 2.3 2 0 0 2 2 2 0 Putative serine esterase (DUF676) Lipase_3 PF01764.20 CBZ51906.1 - 0.094 12.3 0.3 0.19 11.3 0.2 1.4 1 0 0 1 1 1 0 Lipase (class 3) Cupin_4 PF08007.7 CBZ51907.1 - 1.3e-25 90.3 0.0 1.8e-22 80.0 0.0 2.1 2 0 0 2 2 2 2 Cupin superfamily protein Cupin_8 PF13621.1 CBZ51907.1 - 0.022 14.2 0.0 0.043 13.3 0.0 1.4 1 1 0 1 1 1 0 Cupin-like domain Cupin_1 PF00190.17 CBZ51907.1 - 0.1 12.0 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 Cupin Cupin_2 PF07883.6 CBZ51907.1 - 0.12 11.8 0.0 0.27 10.7 0.0 1.5 1 0 0 1 1 1 0 Cupin domain Sporozoite_P67 PF05642.6 CBZ51907.1 - 0.14 9.9 1.2 0.19 9.5 0.9 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen WD40 PF00400.27 CBZ51908.1 - 3.2e-10 39.4 0.1 0.018 14.9 0.0 4.4 4 0 0 4 4 4 3 WD domain, G-beta repeat Nop14 PF04147.7 CBZ51908.1 - 4.2e-06 24.9 26.8 6.7e-06 24.3 18.5 1.3 1 0 0 1 1 1 1 Nop14-like family Daxx PF03344.10 CBZ51908.1 - 1.7e-05 23.5 29.1 1.7e-05 23.5 20.1 1.6 2 0 0 2 2 2 1 Daxx Family CDC45 PF02724.9 CBZ51908.1 - 0.0042 15.1 24.8 0.0094 14.0 16.2 1.9 2 0 0 2 2 2 1 CDC45-like protein Nup160 PF11715.3 CBZ51908.1 - 0.034 12.2 0.2 0.1 10.6 0.1 1.7 1 1 0 1 1 1 0 Nucleoporin Nup120/160 TFIIA PF03153.8 CBZ51908.1 - 0.44 10.3 27.3 0.92 9.3 18.9 1.5 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Ycf1 PF05758.7 CBZ51908.1 - 0.59 7.7 14.7 0.77 7.3 10.2 1.1 1 0 0 1 1 1 0 Ycf1 SAPS PF04499.10 CBZ51908.1 - 1.3 7.5 12.5 1.8 7.1 8.7 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Paf1 PF03985.8 CBZ51908.1 - 1.6 7.4 35.5 0.12 11.0 21.3 1.5 2 0 0 2 2 2 0 Paf1 Hid1 PF12722.2 CBZ51908.1 - 2.4 5.7 10.9 3.2 5.3 7.5 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SpoIIIAH PF12685.2 CBZ51908.1 - 3.9 6.9 18.8 5.1 6.5 12.2 1.7 2 0 0 2 2 2 0 SpoIIIAH-like protein Zip PF02535.17 CBZ51908.1 - 7.1 5.5 9.7 13 4.6 6.7 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter Acyltransferase PF01553.16 CBZ51909.1 - 1.1e-14 53.9 0.0 1.8e-14 53.2 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase Poly_export PF02563.11 CBZ51909.1 - 0.0055 16.4 0.0 0.0092 15.7 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis/export protein Asp PF00026.18 CBZ51909.1 - 0.068 12.4 0.0 4 6.5 0.0 2.0 2 0 0 2 2 2 0 Eukaryotic aspartyl protease Adaptin_N PF01602.15 CBZ51910.1 - 3.3e-157 523.9 13.7 4.1e-157 523.6 9.5 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 CBZ51910.1 - 1.6e-30 106.3 3.2 3.1e-28 98.8 0.0 3.8 3 1 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 CBZ51910.1 - 2.2e-23 82.3 3.0 7.4e-11 42.1 0.0 6.3 1 1 5 6 6 6 5 HEAT repeats B2-adapt-app_C PF09066.5 CBZ51910.1 - 3.5e-15 55.8 0.1 7.5e-15 54.7 0.1 1.6 1 0 0 1 1 1 1 Beta2-adaptin appendage, C-terminal sub-domain HEAT PF02985.17 CBZ51910.1 - 1.2e-09 37.3 7.8 0.0037 17.2 0.0 6.0 7 0 0 7 7 6 2 HEAT repeat Arm PF00514.18 CBZ51910.1 - 1.2e-06 28.0 3.1 0.0014 18.4 0.0 5.0 4 1 1 5 5 5 1 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.1 CBZ51910.1 - 5.1e-06 26.8 4.4 0.15 12.6 0.0 4.6 4 0 0 4 4 3 2 HEAT-like repeat Cnd3 PF12719.2 CBZ51910.1 - 6.9e-06 25.2 2.6 4e-05 22.7 0.3 2.3 2 0 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain Alpha_adaptinC2 PF02883.15 CBZ51910.1 - 1.8e-05 25.0 0.1 4.1e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Adaptin C-terminal domain CLASP_N PF12348.3 CBZ51910.1 - 0.00068 19.0 5.5 0.9 8.8 0.0 4.5 4 1 1 5 5 5 2 CLASP N terminal CDH PF02611.10 CBZ51910.1 - 0.057 12.6 0.0 0.12 11.5 0.0 1.4 1 0 0 1 1 1 0 CDP-diacylglycerol pyrophosphatase RasGEF_N_2 PF14663.1 CBZ51910.1 - 0.086 12.7 1.5 4.1 7.3 0.0 3.7 3 1 1 4 4 4 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain PFK PF00365.15 CBZ51912.1 - 5e-35 120.8 0.0 4.4e-24 84.9 0.0 2.2 2 0 0 2 2 2 2 Phosphofructokinase AP2 PF00847.15 CBZ51913.1 - 3.2e-09 36.7 1.8 0.0017 18.4 0.0 2.6 2 0 0 2 2 2 2 AP2 domain C2 PF00168.25 CBZ51914.1 - 2.9e-09 36.6 0.4 1.5e-07 31.1 0.0 3.4 3 0 0 3 3 3 1 C2 domain MoaC PF01967.16 CBZ51915.1 - 2.7e-42 143.6 1.3 2.3e-37 127.6 0.7 2.9 2 1 0 2 2 2 2 MoaC family Arf PF00025.16 CBZ51916.1 - 2.5e-26 91.9 0.0 3.5e-18 65.4 0.0 3.2 3 0 0 3 3 3 2 ADP-ribosylation factor family G-alpha PF00503.15 CBZ51916.1 - 4.9e-10 38.6 0.0 5.1e-07 28.7 0.0 2.8 4 0 0 4 4 4 2 G-protein alpha subunit Ras PF00071.17 CBZ51916.1 - 0.00044 19.6 0.0 0.054 12.8 0.0 2.9 3 0 0 3 3 3 1 Ras family Gtr1_RagA PF04670.7 CBZ51916.1 - 0.0017 17.5 0.0 0.06 12.4 0.0 2.1 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region Miro PF08477.8 CBZ51916.1 - 0.006 17.0 0.0 2.1 8.8 0.0 2.8 3 0 0 3 3 3 1 Miro-like protein AAA_33 PF13671.1 CBZ51916.1 - 0.0095 15.8 0.1 0.16 11.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain SRPRB PF09439.5 CBZ51916.1 - 0.011 15.0 0.0 3 7.0 0.0 3.0 3 0 0 3 3 3 0 Signal recognition particle receptor beta subunit NACHT PF05729.7 CBZ51916.1 - 0.013 15.1 0.0 0.47 10.1 0.0 2.6 3 0 0 3 3 3 0 NACHT domain Thymidylate_kin PF02223.12 CBZ51916.1 - 0.019 14.3 0.0 0.036 13.4 0.0 1.3 1 0 0 1 1 1 0 Thymidylate kinase AAA_22 PF13401.1 CBZ51916.1 - 0.043 13.9 0.0 0.33 11.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.1 CBZ51916.1 - 0.083 13.7 0.0 0.19 12.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.17 CBZ51916.1 - 0.17 11.3 0.0 0.26 10.7 0.0 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain DUF2217 PF10265.4 CBZ51916.1 - 2.2 6.9 11.6 0.071 11.8 0.5 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2217) AIG2 PF06094.7 CBZ51917.1 - 8.7e-15 55.0 0.1 1.8e-13 50.8 0.1 2.4 1 1 0 1 1 1 1 AIG2-like family AIG2_2 PF13772.1 CBZ51917.1 - 0.12 12.4 0.1 0.37 10.9 0.0 1.9 2 0 0 2 2 2 0 AIG2-like family NfeD PF01957.13 CBZ51921.1 - 0.39 10.8 6.5 0.11 12.6 2.1 1.7 2 0 0 2 2 2 0 NfeD-like C-terminal, partner-binding BTB_2 PF02214.17 CBZ51922.1 - 1.9e-16 59.9 0.0 2.7e-16 59.5 0.0 1.2 1 0 0 1 1 1 1 BTB/POZ domain DEAD PF00270.24 CBZ51925.1 - 1.1e-16 60.7 0.0 6.3e-12 45.3 0.0 2.9 3 0 0 3 3 3 2 DEAD/DEAH box helicase Helicase_C PF00271.26 CBZ51925.1 - 4.8e-06 26.3 0.0 9.6e-06 25.3 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain N2227 PF07942.7 CBZ51926.1 - 2.9e-92 308.4 0.0 4e-92 308.0 0.0 1.1 1 0 0 1 1 1 1 N2227-like protein Methyltransf_23 PF13489.1 CBZ51926.1 - 0.024 14.3 0.0 0.044 13.5 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.7 CBZ51926.1 - 0.051 14.0 0.0 0.14 12.6 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.7 CBZ51926.1 - 0.099 13.1 0.0 0.24 11.8 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain HlyIII PF03006.15 CBZ51927.1 - 2.8e-21 75.9 18.8 2.8e-21 75.9 13.0 1.5 2 0 0 2 2 2 1 Haemolysin-III related KH_1 PF00013.24 CBZ51928.1 - 2.1e-30 104.1 3.2 1.9e-07 30.6 0.0 5.7 6 0 0 6 6 6 4 KH domain KH_3 PF13014.1 CBZ51928.1 - 3.6e-19 67.9 1.9 0.00024 20.6 0.1 6.1 6 0 0 6 6 6 3 KH domain KH_2 PF07650.12 CBZ51928.1 - 0.00049 19.6 0.1 0.56 9.8 0.0 3.3 3 0 0 3 3 3 2 KH domain Macoilin PF09726.4 CBZ51928.1 - 0.1 10.8 13.0 0.14 10.4 9.0 1.2 1 0 0 1 1 1 0 Transmembrane protein Jiraiya PF15038.1 CBZ51929.1 - 0.0078 15.6 3.7 0.0078 15.6 2.6 1.9 1 1 0 2 2 2 1 Jiraiya Orai-1 PF07856.7 CBZ51929.1 - 0.12 11.8 6.4 0.21 11.1 4.2 1.7 1 1 0 1 1 1 0 Mediator of CRAC channel activity V_ATPase_I PF01496.14 CBZ51930.1 - 0.028 12.3 0.1 0.028 12.3 0.1 2.2 3 0 0 3 3 3 0 V-type ATPase 116kDa subunit family Hom_end_hint PF05203.11 CBZ51930.1 - 0.045 13.4 0.0 0.7 9.5 0.0 2.2 1 1 0 1 1 1 0 Hom_end-associated Hint RPAP2_Rtr1 PF04181.8 CBZ51930.1 - 0.051 13.6 0.1 0.14 12.2 0.1 1.7 1 0 0 1 1 1 0 Rtr1/RPAP2 family MbeD_MobD PF04899.7 CBZ51930.1 - 3.7 7.5 9.4 3.9 7.4 0.2 3.7 4 0 0 4 4 4 0 MbeD/MobD like ATG16 PF08614.6 CBZ51931.1 - 0.01 15.6 3.3 0.01 15.6 2.3 3.0 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) HALZ PF02183.13 CBZ51931.1 - 0.67 9.7 7.7 5.4 6.8 0.0 3.2 3 0 0 3 3 3 0 Homeobox associated leucine zipper Tropomyosin_1 PF12718.2 CBZ51931.1 - 2.3 8.0 16.8 0.68 9.7 3.6 2.6 2 1 1 3 3 3 0 Tropomyosin like Kinetocho_Slk19 PF12709.2 CBZ51931.1 - 2.5 8.2 12.6 4.3 7.4 2.1 2.6 3 0 0 3 3 3 0 Central kinetochore-associated APG6 PF04111.7 CBZ51931.1 - 8.2 5.3 12.8 2.7 6.9 3.8 2.1 2 0 0 2 2 2 0 Autophagy protein Apg6 NfeD PF01957.13 CBZ51932.1 - 0.011 15.8 7.3 0.17 12.0 2.7 2.6 2 1 0 2 2 2 0 NfeD-like C-terminal, partner-binding Pro_isomerase PF00160.16 CBZ51933.1 - 8.9e-33 113.6 0.0 1.8e-32 112.7 0.0 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD CUE PF02845.11 CBZ51934.1 - 2e-08 33.5 0.1 9.5e-05 21.7 0.0 2.5 2 0 0 2 2 2 2 CUE domain C2 PF00168.25 CBZ51934.1 - 1.6e-05 24.6 0.0 4.9e-05 23.0 0.0 1.8 2 0 0 2 2 2 1 C2 domain zf-HC5HC2H_2 PF13832.1 CBZ51935.1 - 8.2e-11 41.8 49.7 0.014 15.3 0.6 11.1 11 0 0 11 11 11 7 PHD-zinc-finger like domain PHD_2 PF13831.1 CBZ51935.1 - 0.00055 19.2 3.1 0.00055 19.2 2.2 7.5 8 0 0 8 8 8 5 PHD-finger PIGA PF08288.7 CBZ51936.1 - 2.2e-35 120.8 1.3 9.1e-31 106.0 0.1 2.7 2 0 0 2 2 2 2 PIGA (GPI anchor biosynthesis) Glycos_transf_1 PF00534.15 CBZ51936.1 - 5.9e-27 94.1 0.0 9.2e-27 93.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 CBZ51936.1 - 4.7e-16 59.3 1.5 1.9e-15 57.3 1.0 2.1 1 1 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_transf_4 PF13439.1 CBZ51936.1 - 8.4e-14 51.6 0.2 6.8e-13 48.7 0.2 2.2 1 1 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.1 CBZ51936.1 - 1e-12 48.3 0.0 2.8e-12 46.9 0.0 1.7 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_2 PF13477.1 CBZ51936.1 - 2.3e-05 24.2 0.0 5.1e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase 4-like Glyco_trans_1_2 PF13524.1 CBZ51936.1 - 0.0022 18.2 0.2 0.0063 16.7 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferases group 1 tRNA-synt_1c PF00749.16 CBZ51937.1 - 4.5e-37 127.3 0.0 5.8e-18 64.6 0.0 2.5 2 0 0 2 2 2 2 tRNA synthetases class I (E and Q), catalytic domain PDEase_I PF00233.14 CBZ51938.1 - 3.8e-46 157.7 0.6 8.9e-24 84.5 0.7 2.2 2 0 0 2 2 2 2 3'5'-cyclic nucleotide phosphodiesterase HD PF01966.17 CBZ51938.1 - 0.004 17.1 0.1 0.012 15.5 0.0 1.8 2 0 0 2 2 2 1 HD domain Wzy_C PF04932.10 CBZ51938.1 - 1.6 8.4 6.2 0.76 9.5 1.3 2.1 2 0 0 2 2 2 0 O-Antigen ligase O-antigen_lig PF13425.1 CBZ51938.1 - 5.8 6.8 12.3 7.8 6.4 3.8 2.5 2 0 0 2 2 2 0 O-antigen ligase like membrane protein AMMECR1 PF01871.12 CBZ51940.1 - 1.5e-36 125.1 0.0 1.8e-36 124.8 0.0 1.1 1 0 0 1 1 1 1 AMMECR1 GIDA PF01134.17 CBZ51941.1 - 1.9e-117 392.4 0.0 4.5e-70 236.4 0.0 3.1 2 1 1 3 3 3 3 Glucose inhibited division protein A FAD_oxidored PF12831.2 CBZ51941.1 - 0.00011 21.3 2.1 0.00025 20.2 1.4 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 CBZ51941.1 - 0.00039 20.3 0.2 0.00078 19.3 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 CBZ51941.1 - 0.0021 17.0 2.0 0.0021 17.0 1.4 2.3 3 0 0 3 3 3 1 FAD binding domain HI0933_like PF03486.9 CBZ51941.1 - 0.076 11.4 0.9 0.85 8.0 0.2 2.1 2 0 0 2 2 2 0 HI0933-like protein Thi4 PF01946.12 CBZ51941.1 - 0.23 10.5 0.1 0.42 9.6 0.1 1.3 1 0 0 1 1 1 0 Thi4 family Glyco_hydro_63 PF03200.11 CBZ51942.1 - 3.1e-56 190.7 0.0 1.7e-20 72.5 0.0 5.9 5 1 0 5 5 5 5 Mannosyl oligosaccharide glucosidase Chitin_bind_1 PF00187.14 CBZ51942.1 - 0.024 14.5 9.8 0.05 13.5 6.8 1.5 1 0 0 1 1 1 0 Chitin recognition protein COG7 PF10191.4 CBZ51943.1 - 0.051 11.5 1.2 0.063 11.1 0.0 1.6 2 0 0 2 2 2 0 Golgi complex component 7 (COG7) Baculo_PEP_C PF04513.7 CBZ51943.1 - 0.21 11.3 0.5 0.46 10.2 0.4 1.4 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DEAD PF00270.24 CBZ51944.1 - 3.3e-10 39.7 0.0 1e-09 38.1 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CBZ51944.1 - 1.3e-09 37.8 0.0 2.9e-09 36.6 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain cNMP_binding PF00027.24 CBZ51945.1 - 2.9e-49 164.8 0.0 2e-24 85.1 0.0 2.3 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain YflT PF11181.3 CBZ51945.1 - 0.0054 16.8 0.1 0.96 9.6 0.0 2.5 2 0 0 2 2 2 2 Heat induced stress protein YflT V-SNARE_C PF12352.3 CBZ51946.1 - 7.6e-08 32.3 1.2 7.6e-08 32.3 0.9 2.2 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.8 CBZ51946.1 - 0.014 15.0 2.8 0.023 14.3 0.3 2.2 2 0 0 2 2 2 0 Sec20 V-SNARE PF05008.10 CBZ51946.1 - 0.039 14.1 0.1 0.092 12.9 0.1 1.7 1 0 0 1 1 1 0 Vesicle transport v-SNARE protein N-terminus Kinase-like PF14531.1 CBZ51949.1 - 1.4e-19 70.1 0.0 2.3e-19 69.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase PF00069.20 CBZ51949.1 - 2.1e-19 69.6 0.0 7e-19 67.9 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ51949.1 - 1.1e-07 31.2 0.0 1.7e-07 30.6 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CBZ51949.1 - 0.00084 19.1 1.4 0.019 14.6 0.0 2.6 3 0 0 3 3 3 1 Phosphotransferase enzyme family RIO1 PF01163.17 CBZ51949.1 - 0.056 12.7 0.0 5.3 6.3 0.0 2.3 2 0 0 2 2 2 0 RIO1 family Pkinase PF00069.20 CBZ51950.1 - 6.2e-24 84.5 0.0 1e-23 83.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.1 CBZ51950.1 - 1.1e-20 73.7 0.0 1.7e-20 73.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_Tyr PF07714.12 CBZ51950.1 - 1.8e-10 40.3 0.0 2.4e-10 39.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 CBZ51950.1 - 0.02 13.9 0.0 0.032 13.3 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CBZ51950.1 - 0.024 14.3 0.1 0.08 12.6 0.1 1.9 1 1 0 1 1 1 0 Phosphotransferase enzyme family Kinase-like PF14531.1 CBZ51951.1 - 4.4e-20 71.8 0.0 6.6e-20 71.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase PF00069.20 CBZ51951.1 - 1.8e-19 69.8 0.0 5.9e-19 68.2 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ51951.1 - 2.9e-08 33.0 0.0 4.7e-08 32.4 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CBZ51951.1 - 0.0022 17.7 0.3 0.015 15.0 0.0 2.3 2 0 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 CBZ51951.1 - 0.051 12.9 0.0 5.6 6.2 0.0 2.3 2 0 0 2 2 2 0 RIO1 family Kdo PF06293.9 CBZ51951.1 - 0.098 11.7 0.0 0.17 10.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 CBZ51952.1 - 2.3e-20 72.7 0.0 3.5e-20 72.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase PF00069.20 CBZ51952.1 - 5.1e-20 71.7 0.0 2.2e-19 69.6 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ51952.1 - 4e-08 32.6 0.0 7.7e-08 31.7 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CBZ51952.1 - 0.004 16.9 1.3 0.016 14.9 0.0 2.4 3 0 0 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.9 CBZ51952.1 - 0.095 11.7 0.0 0.17 10.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family HTH_26 PF13443.1 CBZ51952.1 - 0.17 12.0 0.1 0.46 10.7 0.1 1.7 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain NUDIX PF00293.23 CBZ51954.1 - 1.4e-06 27.9 0.1 4e-06 26.5 0.1 1.9 1 1 0 1 1 1 1 NUDIX domain TPR_6 PF13174.1 CBZ51954.1 - 0.065 13.7 0.3 0.61 10.6 0.0 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat Proteasome PF00227.21 CBZ51955.1 - 2.3e-32 111.8 1.1 7.8e-26 90.5 0.0 2.3 2 0 0 2 2 2 2 Proteasome subunit Proteasome_A_N PF10584.4 CBZ51955.1 - 4.7e-15 54.5 0.0 9.2e-15 53.6 0.0 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature DHDPS PF00701.17 CBZ51956.1 - 1e-88 296.7 0.0 1.1e-88 296.5 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family PA PF02225.17 CBZ51956.1 - 0.012 15.3 0.1 0.025 14.2 0.1 1.5 1 0 0 1 1 1 0 PA domain Tsp45I PF06300.7 CBZ51956.1 - 0.042 13.2 0.0 0.062 12.7 0.0 1.3 1 0 0 1 1 1 0 Tsp45I type II restriction enzyme zf-B_box PF00643.19 CBZ51957.1 - 1.3e-11 44.1 8.9 1.2e-05 25.0 0.5 2.4 2 0 0 2 2 2 2 B-box zinc finger SNARE PF05739.14 CBZ51957.1 - 0.094 12.4 0.2 0.2 11.3 0.2 1.5 1 0 0 1 1 1 0 SNARE domain LTXXQ PF07813.7 CBZ51957.1 - 1.6 9.2 6.7 0.64 10.5 0.2 2.6 2 0 0 2 2 2 0 LTXXQ motif family protein Ribosomal_S7 PF00177.16 CBZ51958.1 - 4.3e-43 146.4 0.9 5e-43 146.2 0.6 1.0 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e Ribosomal_S14 PF00253.16 CBZ51959.1 - 1.2e-17 63.0 6.3 1.2e-17 62.9 4.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e DUF2318 PF10080.4 CBZ51959.1 - 0.028 14.1 0.2 0.03 14.0 0.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2318) zf-CCHC_2 PF13696.1 CBZ51959.1 - 0.3 10.5 2.1 0.35 10.4 0.1 1.9 2 0 0 2 2 2 0 Zinc knuckle Rsm1 PF08600.5 CBZ51959.1 - 6.2 6.7 5.6 14 5.5 0.5 2.1 1 1 1 2 2 2 0 Rsm1-like TPR_16 PF13432.1 CBZ51960.1 - 2.8e-24 85.1 41.0 6.5e-07 29.8 2.8 10.2 6 2 4 11 11 11 5 Tetratricopeptide repeat TPR_11 PF13414.1 CBZ51960.1 - 2.2e-22 78.4 20.5 1e-05 25.0 1.0 8.7 7 1 1 8 8 8 4 TPR repeat TPR_19 PF14559.1 CBZ51960.1 - 1.1e-18 67.3 30.2 1.9e-05 24.8 0.5 9.5 8 2 1 9 9 9 6 Tetratricopeptide repeat TPR_2 PF07719.12 CBZ51960.1 - 3e-16 57.9 30.6 0.029 14.2 0.2 13.6 15 0 0 15 15 14 3 Tetratricopeptide repeat TPR_8 PF13181.1 CBZ51960.1 - 2.7e-15 54.9 4.6 0.11 12.3 0.1 9.7 9 1 1 10 10 10 3 Tetratricopeptide repeat TPR_14 PF13428.1 CBZ51960.1 - 1.4e-13 50.1 54.4 0.026 15.1 0.5 14.1 9 4 5 14 14 13 6 Tetratricopeptide repeat TPR_12 PF13424.1 CBZ51960.1 - 3.2e-13 49.4 35.8 0.00042 20.2 1.7 10.0 6 3 2 9 9 9 6 Tetratricopeptide repeat TPR_7 PF13176.1 CBZ51960.1 - 7.3e-11 41.0 18.3 1.2 9.0 0.2 9.9 9 0 0 9 9 9 2 Tetratricopeptide repeat Apc3 PF12895.2 CBZ51960.1 - 4.9e-10 39.3 14.0 0.00033 20.7 0.0 7.3 5 2 3 9 9 8 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 CBZ51960.1 - 6.3e-07 29.4 22.3 0.75 10.3 0.2 11.2 12 0 0 12 12 12 1 Tetratricopeptide repeat TPR_17 PF13431.1 CBZ51960.1 - 8.8e-07 28.6 5.9 3.3 8.1 0.0 7.8 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_1 PF00515.23 CBZ51960.1 - 8.6e-06 25.1 19.3 0.033 13.7 0.2 9.2 12 1 0 12 12 10 2 Tetratricopeptide repeat TPR_9 PF13371.1 CBZ51960.1 - 1.7e-05 24.5 34.7 0.006 16.4 0.7 8.1 7 1 1 8 8 8 3 Tetratricopeptide repeat NARP1 PF12569.3 CBZ51960.1 - 0.00041 19.2 0.4 0.96 8.1 0.0 3.4 3 0 0 3 3 3 1 NMDA receptor-regulated protein 1 TPR_21 PF09976.4 CBZ51960.1 - 0.0005 20.0 14.8 0.047 13.6 0.1 4.8 4 1 1 5 5 4 1 Tetratricopeptide repeat TPR_4 PF07721.9 CBZ51960.1 - 0.001 19.2 0.7 0.001 19.2 0.5 8.4 8 0 0 8 8 7 2 Tetratricopeptide repeat HeLo PF14479.1 CBZ51960.1 - 0.0047 16.7 1.5 0.012 15.4 1.0 1.7 1 0 0 1 1 1 1 Prion-inhibition and propagation TPR_15 PF13429.1 CBZ51960.1 - 0.0094 15.0 1.2 0.0094 15.0 0.9 5.4 6 1 1 7 7 7 1 Tetratricopeptide repeat Coatomer_E PF04733.9 CBZ51960.1 - 0.037 13.2 1.4 12 4.9 0.0 4.1 4 1 0 4 4 4 0 Coatomer epsilon subunit ChAPs PF09295.5 CBZ51960.1 - 0.1 11.3 0.0 0.23 10.1 0.0 1.5 1 0 0 1 1 1 0 ChAPs (Chs5p-Arf1p-binding proteins) HAP1_N PF04849.8 CBZ51961.1 - 0.029 13.3 1.6 0.047 12.6 1.1 1.3 1 0 0 1 1 1 0 HAP1 N-terminal conserved region YqzE PF14038.1 CBZ51961.1 - 0.051 13.3 2.4 0.093 12.4 0.0 2.6 3 0 0 3 3 3 0 YqzE-like protein Phage_Mu_Gam PF07352.7 CBZ51961.1 - 0.36 10.3 4.1 1.1 8.7 0.1 2.6 3 0 0 3 3 3 0 Bacteriophage Mu Gam like protein ELO PF01151.13 CBZ51962.1 - 3.8e-49 167.2 17.5 4.9e-49 166.8 12.1 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family ECH PF00378.15 CBZ51963.1 - 4.6e-24 84.8 0.0 5.9e-24 84.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Pkinase PF00069.20 CBZ51964.1 - 1.5e-58 197.9 0.3 9.1e-29 100.3 0.0 2.2 1 1 1 2 2 2 2 Protein kinase domain EF-hand_1 PF00036.27 CBZ51964.1 - 1.6e-27 92.6 9.9 6.8e-08 31.2 1.6 4.9 5 0 0 5 5 5 4 EF hand EF-hand_7 PF13499.1 CBZ51964.1 - 2.7e-26 91.4 0.3 6.7e-13 48.5 0.0 2.6 2 0 0 2 2 2 2 EF-hand domain pair Pkinase_Tyr PF07714.12 CBZ51964.1 - 2.9e-24 85.5 0.0 4e-15 55.6 0.1 2.2 1 1 1 2 2 2 2 Protein tyrosine kinase EF-hand_6 PF13405.1 CBZ51964.1 - 5.2e-21 72.5 6.6 8.1e-05 22.1 0.0 4.7 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.1 CBZ51964.1 - 1.9e-19 69.0 7.8 1.2e-05 24.8 0.8 4.4 3 1 1 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.1 CBZ51964.1 - 1.4e-18 65.3 8.1 8.2e-05 21.7 0.0 4.5 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.1 CBZ51964.1 - 4e-05 23.4 0.3 1.5 8.7 0.0 3.5 2 1 1 3 3 3 2 EF-hand domain EF-hand_4 PF12763.2 CBZ51964.1 - 0.00025 20.7 1.1 0.58 9.9 0.0 3.2 2 1 1 3 3 3 2 Cytoskeletal-regulatory complex EF hand Kinase-like PF14531.1 CBZ51964.1 - 0.024 13.5 0.0 0.086 11.7 0.0 1.8 2 0 0 2 2 2 0 Kinase-like Toprim_2 PF13155.1 CBZ51964.1 - 0.037 14.3 0.8 1.3 9.3 0.0 2.8 2 1 0 3 3 3 0 Toprim-like SPARC_Ca_bdg PF10591.4 CBZ51964.1 - 0.064 13.2 0.0 15 5.6 0.0 3.2 3 0 0 3 3 3 0 Secreted protein acidic and rich in cysteine Ca binding region Amino_oxidase PF01593.19 CBZ51965.1 - 2.3e-38 132.4 1.2 2.1e-28 99.5 0.1 2.5 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 CBZ51965.1 - 1.8e-12 47.0 1.2 7.6e-12 45.0 0.2 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 CBZ51965.1 - 1.4e-05 25.4 0.0 4.2e-05 23.8 0.1 1.7 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 CBZ51965.1 - 2.7e-05 24.1 0.1 6.4e-05 22.9 0.1 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 CBZ51965.1 - 8.3e-05 21.7 0.0 0.00015 20.9 0.0 1.3 1 0 0 1 1 1 1 Thi4 family GIDA PF01134.17 CBZ51965.1 - 0.00046 19.1 0.3 0.00068 18.6 0.2 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.1 CBZ51965.1 - 0.00068 19.7 0.1 0.0012 18.8 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 CBZ51965.1 - 0.0018 16.7 0.2 0.0026 16.3 0.2 1.2 1 0 0 1 1 1 1 HI0933-like protein Lycopene_cycl PF05834.7 CBZ51965.1 - 0.034 13.0 1.9 0.034 13.0 0.1 1.8 2 0 0 2 2 2 0 Lycopene cyclase protein AlaDh_PNT_C PF01262.16 CBZ51965.1 - 0.15 11.5 0.3 0.31 10.6 0.2 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Ctr PF04145.10 CBZ51965.1 - 10 6.1 3.8 19 5.2 0.3 3.4 3 0 0 3 3 3 0 Ctr copper transporter family Mito_carr PF00153.22 CBZ51967.1 - 1.5e-42 143.2 6.3 3.8e-24 84.2 0.3 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Fe_hyd_lg_C PF02906.9 CBZ51969.1 - 6.2e-52 176.6 0.0 6.2e-42 143.8 0.0 3.9 2 1 0 2 2 2 2 Iron only hydrogenase large subunit, C-terminal domain Peptidase_C3 PF00548.15 CBZ51970.1 - 0.041 13.6 0.0 0.073 12.8 0.0 1.4 1 0 0 1 1 1 0 3C cysteine protease (picornain 3C) 6PGD PF00393.14 CBZ51971.1 - 2.9e-52 177.7 2.4 8e-28 97.4 0.6 2.7 1 1 1 2 2 2 2 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 CBZ51971.1 - 4.4e-34 117.6 0.0 5.9e-34 117.2 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.13 CBZ51971.1 - 0.013 15.1 0.0 0.022 14.3 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_11 PF14833.1 CBZ51971.1 - 0.043 13.8 0.0 0.087 12.8 0.0 1.5 1 0 0 1 1 1 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase WD40 PF00400.27 CBZ51972.1 - 9.4e-18 63.3 4.9 1.1e-07 31.4 0.0 4.6 5 0 0 5 5 5 2 WD domain, G-beta repeat BBS2_Mid PF14783.1 CBZ51972.1 - 0.13 12.0 0.0 11 5.8 0.0 2.4 1 1 1 2 2 2 0 Ciliary BBSome complex subunit 2, middle region AAA_5 PF07728.9 CBZ51973.1 - 3e-96 318.5 0.0 2.6e-20 72.5 0.0 11.4 10 1 0 10 10 10 9 AAA domain (dynein-related subfamily) AAA PF00004.24 CBZ51973.1 - 4.6e-20 72.1 0.0 0.059 13.5 0.0 6.9 6 0 0 6 6 6 5 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 CBZ51973.1 - 3.2e-18 66.3 26.2 0.00017 21.6 0.0 9.9 10 0 0 10 10 8 5 AAA ATPase domain AAA_22 PF13401.1 CBZ51973.1 - 4.9e-16 59.0 0.0 0.023 14.8 0.0 7.8 6 1 0 6 6 6 3 AAA domain Mg_chelatase PF01078.16 CBZ51973.1 - 1.9e-13 50.0 1.6 0.018 14.2 0.0 8.2 8 1 1 9 9 9 2 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 CBZ51973.1 - 3.1e-13 49.4 0.0 7.7e-05 22.3 0.0 6.8 9 0 0 9 9 7 2 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 CBZ51973.1 - 1e-11 45.7 0.0 0.055 14.2 0.0 5.8 5 0 0 5 5 4 1 AAA domain AAA_33 PF13671.1 CBZ51973.1 - 4.3e-11 42.8 0.0 0.039 13.8 0.0 6.2 5 0 0 5 5 5 2 AAA domain NACHT PF05729.7 CBZ51973.1 - 1.1e-10 41.4 0.8 0.015 14.9 0.0 5.6 5 0 0 5 5 5 2 NACHT domain AAA_29 PF13555.1 CBZ51973.1 - 1.2e-09 37.5 0.2 2.8 7.5 0.0 6.3 6 0 0 6 6 6 1 P-loop containing region of AAA domain AAA_14 PF13173.1 CBZ51973.1 - 1.5e-09 37.8 0.0 0.051 13.4 0.0 6.5 7 1 0 7 7 6 2 AAA domain ABC_tran PF00005.22 CBZ51973.1 - 3.8e-09 36.9 0.0 0.59 10.4 0.0 6.0 6 0 0 6 6 6 1 ABC transporter Sigma54_activ_2 PF14532.1 CBZ51973.1 - 1.3e-07 31.7 3.1 0.32 11.0 0.0 6.8 8 0 0 8 8 6 1 Sigma-54 interaction domain AAA_18 PF13238.1 CBZ51973.1 - 5.2e-07 30.0 0.0 7.3 6.9 0.0 6.1 6 0 0 6 6 6 0 AAA domain UPF0079 PF02367.12 CBZ51973.1 - 8.1e-07 28.7 0.4 3.5 7.2 0.2 5.4 5 0 0 5 5 5 1 Uncharacterised P-loop hydrolase UPF0079 Sigma54_activat PF00158.21 CBZ51973.1 - 1.6e-05 24.4 0.0 20 4.6 0.0 6.7 7 0 0 7 7 7 0 Sigma-54 interaction domain T2SE PF00437.15 CBZ51973.1 - 1.9e-05 23.7 0.0 0.7 8.7 0.0 5.4 6 0 0 6 6 6 1 Type II/IV secretion system protein Miro PF08477.8 CBZ51973.1 - 3.5e-05 24.2 0.0 5.4 7.5 0.0 4.6 4 0 0 4 4 4 0 Miro-like protein MobB PF03205.9 CBZ51973.1 - 0.00021 21.0 0.0 0.48 10.1 0.0 4.7 5 0 0 5 5 5 1 Molybdopterin guanine dinucleotide synthesis protein B Arch_ATPase PF01637.13 CBZ51973.1 - 0.00057 19.6 0.0 0.24 11.0 0.0 3.0 3 0 0 3 3 2 1 Archaeal ATPase Dynein_heavy PF03028.10 CBZ51973.1 - 0.00074 17.6 0.0 0.021 12.8 0.0 2.8 4 0 0 4 4 4 1 Dynein heavy chain and region D6 of dynein motor RNA_helicase PF00910.17 CBZ51973.1 - 0.00099 19.2 0.1 26 5.0 0.0 5.3 6 0 0 6 6 5 0 RNA helicase DUF815 PF05673.8 CBZ51973.1 - 0.005 15.8 0.7 1.1 8.1 0.0 3.7 4 0 0 4 4 4 1 Protein of unknown function (DUF815) MCM PF00493.18 CBZ51973.1 - 0.023 13.5 0.0 11 4.7 0.0 3.1 4 0 0 4 4 4 0 MCM2/3/5 family Rad17 PF03215.10 CBZ51973.1 - 0.03 13.0 0.1 3.7 6.1 0.0 3.7 5 0 0 5 5 5 0 Rad17 cell cycle checkpoint protein VWA PF00092.23 CBZ51973.1 - 0.042 13.5 0.0 0.087 12.5 0.0 1.4 1 0 0 1 1 1 0 von Willebrand factor type A domain AAA_24 PF13479.1 CBZ51973.1 - 0.048 13.2 0.1 23 4.4 0.0 3.7 4 0 0 4 4 4 0 AAA domain ResIII PF04851.10 CBZ51973.1 - 0.33 10.7 0.0 1.1e+02 2.5 0.0 4.5 5 0 0 5 5 5 0 Type III restriction enzyme, res subunit cobW PF02492.14 CBZ51973.1 - 0.49 9.8 0.5 34 3.8 0.0 3.7 4 0 0 4 4 4 0 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.4 CBZ51973.1 - 0.74 9.2 0.4 33 3.9 0.0 3.3 4 0 0 4 4 3 0 Ethanolamine utilisation - propanediol utilisation SRP54 PF00448.17 CBZ51973.1 - 0.8 9.1 0.5 3.2e+02 0.6 0.0 4.5 6 0 0 6 6 6 0 SRP54-type protein, GTPase domain TIP49 PF06068.8 CBZ51973.1 - 0.92 8.1 0.2 1.1e+02 1.3 0.0 3.4 5 0 0 5 5 5 0 TIP49 C-terminus SRPRB PF09439.5 CBZ51973.1 - 1.2 8.3 0.0 16 4.6 0.0 2.9 3 0 0 3 3 3 0 Signal recognition particle receptor beta subunit PRK PF00485.13 CBZ51973.1 - 3.3 7.2 0.0 41 3.6 0.0 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family KTI12 PF08433.5 CBZ51973.1 - 3.6 6.7 0.0 8.1 5.5 0.0 1.5 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_7 PF12775.2 CBZ51973.1 - 3.7 6.5 0.0 56 2.6 0.0 2.4 3 0 0 3 3 2 0 P-loop containing dynein motor region D3 Bac_DnaA PF00308.13 CBZ51973.1 - 4.3 6.9 0.0 65 3.0 0.0 2.3 2 0 0 2 2 2 0 Bacterial dnaA protein NTPase_1 PF03266.10 CBZ51973.1 - 5.1 6.7 0.0 2.6e+02 1.2 0.0 3.3 4 0 0 4 4 3 0 NTPase AAA_PrkA PF08298.6 CBZ51973.1 - 5.2 5.6 0.0 99 1.4 0.0 2.3 2 0 0 2 2 2 0 PrkA AAA domain KaiC PF06745.8 CBZ51973.1 - 7.4 5.6 0.7 66 2.5 0.0 2.8 4 0 0 4 4 3 0 KaiC RadC PF04002.10 CBZ51974.1 - 1.1 9.0 0.3 2.1 8.0 0.2 1.4 1 0 0 1 1 1 0 RadC-like JAB domain PIG-Y PF15159.1 CBZ51975.1 - 3.2e-15 56.0 0.7 8.6e-13 48.3 0.0 2.2 2 0 0 2 2 2 2 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y Vps35 PF03635.12 CBZ51976.1 - 6.6e-261 867.7 0.0 7.6e-261 867.5 0.0 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 SPX PF03105.14 CBZ51977.1 - 0.86 9.3 12.6 0.16 11.7 0.5 3.2 2 2 0 2 2 2 0 SPX domain Ribosomal_L24e PF01246.15 CBZ51978.1 - 2.2e-28 97.9 3.8 5.3e-28 96.6 2.6 1.7 1 0 0 1 1 1 1 Ribosomal protein L24e zf-FCS PF06467.9 CBZ51978.1 - 0.0033 17.0 3.5 0.0065 16.0 2.3 1.6 1 1 0 1 1 1 1 MYM-type Zinc finger with FCS sequence motif Asp PF00026.18 CBZ51980.1 - 5.2e-22 78.4 0.0 1.6e-15 57.1 0.0 3.7 2 2 0 2 2 2 2 Eukaryotic aspartyl protease TAXi_C PF14541.1 CBZ51980.1 - 1.4e-18 66.9 0.0 3.3e-18 65.7 0.0 1.6 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal TAXi_N PF14543.1 CBZ51980.1 - 1.5e-14 54.2 0.5 1.5e-14 54.2 0.3 1.7 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal TPPK_C PF12555.3 CBZ51980.1 - 0.81 9.4 6.4 3.3 7.4 4.3 2.2 2 0 0 2 2 2 0 Thiamine pyrophosphokinase C terminal Guanylate_kin PF00625.16 CBZ51981.1 - 3.1e-44 150.6 0.0 4.4e-44 150.1 0.0 1.2 1 0 0 1 1 1 1 Guanylate kinase Reo_sigmaC PF04582.7 CBZ51984.1 - 0.018 14.2 23.9 0.062 12.4 0.6 5.0 5 1 1 6 6 6 0 Reovirus sigma C capsid protein Sec10 PF07393.6 CBZ51985.1 - 0.64 8.1 3.5 1 7.4 2.4 1.2 1 0 0 1 1 1 0 Exocyst complex component Sec10 Urease_alpha PF00449.15 CBZ51986.1 - 0.033 14.3 0.1 0.22 11.6 0.1 2.1 2 0 0 2 2 2 0 Urease alpha-subunit, N-terminal domain Ribosomal_S8e PF01201.17 CBZ51987.1 - 6.4e-28 97.5 0.0 1e-27 96.8 0.0 1.3 1 1 0 1 1 1 1 Ribosomal protein S8e BUD22 PF09073.5 CBZ51990.1 - 0.0042 16.2 29.3 0.0052 15.9 20.3 1.2 1 0 0 1 1 1 1 BUD22 Gly-zipper_OmpA PF13436.1 CBZ51990.1 - 1.5 8.4 14.2 3.1 7.4 9.0 2.0 1 1 1 2 2 2 0 Glycine-zipper containing OmpA-like membrane domain XRN_N PF03159.13 CBZ51991.1 - 2.3e-91 305.3 0.0 3.3e-91 304.9 0.0 1.2 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus TPR_MLP1_2 PF07926.7 CBZ51993.1 - 0.013 15.2 11.4 0.013 15.2 7.9 5.2 1 1 4 5 5 5 0 TPR/MLP1/MLP2-like protein DUF904 PF06005.7 CBZ51993.1 - 0.013 15.7 5.6 0.013 15.7 3.9 8.5 2 1 4 6 6 5 0 Protein of unknown function (DUF904) APG6 PF04111.7 CBZ51993.1 - 0.02 13.9 75.3 0.089 11.8 11.8 4.9 1 1 3 5 5 5 0 Autophagy protein Apg6 GAS PF13851.1 CBZ51993.1 - 0.026 13.7 73.6 0.37 9.9 15.1 4.5 2 1 3 5 5 5 0 Growth-arrest specific micro-tubule binding Vac_Fusion PF02346.11 CBZ51993.1 - 0.058 12.8 15.0 0.25 10.8 0.9 4.6 4 0 0 4 4 4 0 Chordopoxvirus fusion protein CCDC155 PF14662.1 CBZ51993.1 - 0.073 12.6 80.0 0.11 12.1 9.4 4.7 2 1 3 5 5 5 0 Coiled-coil region of CCDC155 DUF869 PF05911.6 CBZ51993.1 - 0.29 9.3 56.0 0.71 8.0 20.2 3.2 2 1 1 3 3 3 0 Plant protein of unknown function (DUF869) ERM PF00769.14 CBZ51993.1 - 0.42 10.1 83.2 0.21 11.1 2.8 5.2 2 1 4 6 6 6 0 Ezrin/radixin/moesin family Myosin_tail_1 PF01576.14 CBZ51993.1 - 2.6 5.6 80.7 0.24 9.0 1.0 4.3 2 1 2 4 4 4 0 Myosin tail ADIP PF11559.3 CBZ51993.1 - 4.2 7.2 78.5 0.24 11.3 5.1 5.6 2 1 3 6 6 6 0 Afadin- and alpha -actinin-Binding DUF972 PF06156.8 CBZ51993.1 - 6.8 7.0 62.4 0.18 12.1 3.9 6.6 2 1 6 8 8 8 0 Protein of unknown function (DUF972) SET PF00856.23 CBZ51994.1 - 2.7e-09 37.5 0.0 3.2e-06 27.5 0.0 2.5 2 1 0 2 2 2 2 SET domain Flavoprotein PF02441.14 CBZ51995.1 - 5.4e-42 142.5 0.0 7.2e-42 142.1 0.0 1.2 1 0 0 1 1 1 1 Flavoprotein DUF3437 PF11919.3 CBZ51996.1 - 2.9e-24 84.5 0.1 1e-23 82.7 0.0 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3437) HEAT PF02985.17 CBZ51996.1 - 0.0053 16.7 2.6 0.95 9.7 0.0 4.0 3 0 0 3 3 3 2 HEAT repeat DUF732 PF05305.9 CBZ51997.1 - 0.051 13.6 0.5 0.96 9.5 0.0 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF732) TFIIA PF03153.8 CBZ51998.1 - 2.1 8.1 10.0 3.2 7.5 6.9 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit AreA_N PF07573.6 CBZ52001.1 - 1.3 9.6 10.5 2.6 8.6 2.6 2.5 2 0 0 2 2 2 0 Nitrogen regulatory protein AreA N terminus MCLC PF05934.6 CBZ52002.1 - 5.5 5.1 8.4 7.8 4.6 5.8 1.1 1 0 0 1 1 1 0 Mid-1-related chloride channel (MCLC) DUF605 PF04652.11 CBZ52003.1 - 2.3 7.4 9.5 2.8 7.2 6.6 1.2 1 0 0 1 1 1 0 Vta1 like Mucin PF01456.12 CBZ52004.1 - 3.3 7.4 33.3 0.32 10.7 9.7 3.2 3 0 0 3 3 3 0 Mucin-like glycoprotein DUF605 PF04652.11 CBZ52006.1 - 1.4 8.2 16.5 1.7 7.9 11.4 1.1 1 0 0 1 1 1 0 Vta1 like DUF605 PF04652.11 CBZ52007.1 - 6.5 6.0 11.4 8.9 5.5 7.9 1.2 1 0 0 1 1 1 0 Vta1 like APG6 PF04111.7 CBZ52009.1 - 2.5 7.0 10.9 0.079 11.9 2.0 2.3 2 0 0 2 2 2 0 Autophagy protein Apg6 Peptidase_C97 PF05903.9 CBZ52010.1 - 4.5e-23 81.6 0.0 7e-23 81.0 0.0 1.3 1 0 0 1 1 1 1 PPPDE putative peptidase domain WD40 PF00400.27 CBZ52011.1 - 4.2e-20 70.8 9.1 0.00034 20.3 0.1 7.0 8 0 0 8 8 8 5 WD domain, G-beta repeat PQQ_2 PF13360.1 CBZ52011.1 - 0.0091 15.4 0.0 0.038 13.4 0.0 1.9 3 0 0 3 3 3 1 PQQ-like domain BBS2_Mid PF14783.1 CBZ52011.1 - 0.027 14.2 0.0 4.7 7.0 0.0 3.4 3 1 1 4 4 4 0 Ciliary BBSome complex subunit 2, middle region SAPS PF04499.10 CBZ52011.1 - 0.44 9.1 3.7 0.54 8.8 2.5 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein NARP1 PF12569.3 CBZ52011.1 - 5.4 5.6 10.4 13 4.3 5.8 2.0 2 0 0 2 2 2 0 NMDA receptor-regulated protein 1 Nop14 PF04147.7 CBZ52011.1 - 6.8 4.4 21.1 10 3.8 14.6 1.2 1 0 0 1 1 1 0 Nop14-like family Myosin_head PF00063.16 CBZ52012.1 - 7e-181 602.7 3.6 1e-180 602.2 2.5 1.2 1 0 0 1 1 1 1 Myosin head (motor domain) RCC1 PF00415.13 CBZ52012.1 - 1.2e-28 99.1 10.4 1.1e-07 31.9 0.0 6.0 6 0 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 CBZ52012.1 - 1.6e-27 94.4 25.7 8.8e-11 41.1 0.4 6.6 6 0 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat IQ PF00612.22 CBZ52012.1 - 1.2e-18 64.8 39.2 0.0012 18.2 0.1 8.0 7 0 0 7 7 7 6 IQ calmodulin-binding motif Myosin_N PF02736.14 CBZ52012.1 - 0.0048 16.5 0.4 0.0098 15.5 0.3 1.6 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain AAA_22 PF13401.1 CBZ52012.1 - 0.0063 16.6 0.3 0.03 14.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 CBZ52012.1 - 0.023 14.6 0.0 0.053 13.5 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain Zeta_toxin PF06414.7 CBZ52012.1 - 0.029 13.4 1.1 0.054 12.5 0.1 1.9 2 0 0 2 2 2 0 Zeta toxin AAA_19 PF13245.1 CBZ52012.1 - 0.034 13.8 0.1 0.15 11.7 0.0 2.0 2 0 0 2 2 2 0 Part of AAA domain BRCA2 PF00634.13 CBZ52013.1 - 4.8e-36 121.6 7.9 0.00013 21.1 0.0 6.9 6 0 0 6 6 6 6 BRCA2 repeat BRCA-2_OB1 PF09103.5 CBZ52013.1 - 1.4e-11 44.1 0.0 4.9e-11 42.3 0.0 1.8 1 1 0 1 1 1 1 BRCA2, oligonucleotide/oligosaccharide-binding, domain 1 Con-6 PF10346.4 CBZ52013.1 - 5e-06 25.8 6.8 35 3.9 0.1 6.4 6 0 0 6 6 6 0 Conidiation protein 6 BAH PF01426.13 CBZ52013.1 - 0.12 12.1 3.4 1.2e+02 2.4 0.0 4.7 5 0 0 5 5 5 0 BAH domain Biotin_lipoyl_2 PF13533.1 CBZ52013.1 - 2.4 7.8 8.0 2.1e+02 1.6 0.0 5.6 6 0 0 6 6 6 0 Biotin-lipoyl like Plasmodium_Vir PF05795.6 CBZ52013.1 - 4.2 6.4 4.1 13 4.8 2.8 1.9 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Met_10 PF02475.11 CBZ52014.1 - 8.2e-44 149.5 0.0 1.3e-43 148.9 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein TRM PF02005.11 CBZ52014.1 - 2.3e-05 23.4 0.1 3.7e-05 22.8 0.1 1.2 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase Methyltransf_26 PF13659.1 CBZ52014.1 - 0.00055 19.9 0.0 0.0012 18.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CBZ52014.1 - 0.0056 16.2 0.0 0.012 15.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CBZ52014.1 - 0.011 16.3 0.1 0.033 14.7 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain MTS PF05175.9 CBZ52014.1 - 0.014 14.7 0.0 0.027 13.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain DNA_methylase PF00145.12 CBZ52014.1 - 0.068 12.2 0.0 0.068 12.2 0.0 2.6 2 1 0 2 2 2 0 C-5 cytosine-specific DNA methylase DUF4047 PF13256.1 CBZ52015.1 - 0.21 11.5 0.8 0.47 10.4 0.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4047) Cgr1 PF03879.9 CBZ52015.1 - 9.5 6.4 12.1 0.069 13.3 0.8 2.9 3 0 0 3 3 3 0 Cgr1 family Peptidase_C14 PF00656.17 CBZ52016.1 - 2.8e-21 76.3 0.0 5.8e-21 75.3 0.0 1.5 1 0 0 1 1 1 1 Caspase domain SPACA7 PF15307.1 CBZ52016.1 - 0.00084 19.4 0.1 0.31 11.1 0.0 3.2 3 0 0 3 3 3 2 Sperm acrosome-associated protein 7 Pkinase PF00069.20 CBZ52019.1 - 1.2e-33 116.3 0.0 3e-17 62.6 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ52019.1 - 2.5e-08 33.3 0.0 0.00036 19.6 0.0 2.6 2 1 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 CBZ52019.1 - 0.0019 17.2 0.0 0.83 8.5 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Peptidase_C26 PF07722.8 CBZ52020.1 - 8.9e-20 71.0 0.0 2.2e-16 59.9 0.0 2.2 2 0 0 2 2 2 2 Peptidase C26 GATase PF00117.23 CBZ52020.1 - 6.2e-08 32.3 0.0 0.0096 15.3 0.1 2.2 2 0 0 2 2 2 2 Glutamine amidotransferase class-I DJ-1_PfpI PF01965.19 CBZ52020.1 - 0.043 13.2 0.1 0.12 11.8 0.0 1.7 2 0 0 2 2 2 0 DJ-1/PfpI family DUF3818 PF12825.2 CBZ52022.1 - 0.065 11.8 0.0 0.096 11.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function in PX-proteins (DUF3818) Ribosomal_L29 PF00831.18 CBZ52022.1 - 0.081 12.6 0.7 0.26 10.9 0.0 2.2 2 0 0 2 2 2 0 Ribosomal L29 protein DUF2012 PF09430.5 CBZ52023.1 - 2.7e-08 33.6 0.0 4.4e-08 33.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2012) PX PF00787.19 CBZ52024.1 - 2e-06 27.5 0.7 1.4e-05 24.7 0.5 2.1 1 1 0 1 1 1 1 PX domain Nucleoporin_N PF08801.6 CBZ52024.1 - 0.00033 19.5 0.0 0.00074 18.3 0.0 1.5 1 0 0 1 1 1 1 Nup133 N terminal like WD40 PF00400.27 CBZ52024.1 - 0.022 14.6 1.0 7.3 6.6 0.0 4.6 5 0 0 5 5 5 0 WD domain, G-beta repeat TPR_11 PF13414.1 CBZ52025.1 - 2.8e-08 33.2 0.2 0.00015 21.3 0.0 2.5 2 0 0 2 2 2 2 TPR repeat Fis1_TPR_C PF14853.1 CBZ52025.1 - 2.7e-07 30.3 0.1 0.0033 17.2 0.2 2.5 1 1 1 2 2 2 2 Fis1 C-terminal tetratricopeptide repeat TPR_16 PF13432.1 CBZ52025.1 - 8.4e-07 29.5 0.0 0.00035 21.1 0.0 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.12 CBZ52025.1 - 1.2e-06 27.9 0.2 0.16 11.9 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 CBZ52025.1 - 4.2e-06 26.9 0.5 0.0017 18.8 0.3 3.5 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.23 CBZ52025.1 - 6e-06 25.6 0.3 0.056 13.0 0.1 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 CBZ52025.1 - 1.4e-05 25.3 0.8 0.00017 21.8 0.1 2.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_5 PF12688.2 CBZ52025.1 - 0.0041 17.1 0.2 0.0092 16.0 0.2 1.5 1 0 0 1 1 1 1 Tetratrico peptide repeat TPR_17 PF13431.1 CBZ52025.1 - 0.0046 17.0 0.7 0.31 11.3 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.1 CBZ52025.1 - 0.0057 17.0 0.1 0.28 11.7 0.0 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat Apc3 PF12895.2 CBZ52025.1 - 0.0071 16.4 0.0 0.023 14.8 0.0 1.8 1 1 1 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 CBZ52025.1 - 0.033 14.0 0.2 0.64 9.9 0.1 2.8 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.1 CBZ52025.1 - 0.092 12.5 0.0 3.8 7.4 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat OTU PF02338.14 CBZ52026.1 - 1.8e-17 64.0 0.0 3.8e-17 62.9 0.0 1.6 1 0 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.4 CBZ52026.1 - 3.9e-07 29.6 0.1 0.0024 17.2 0.0 2.2 1 1 1 2 2 2 2 Peptidase C65 Otubain Bromodomain PF00439.20 CBZ52027.1 - 5.2e-22 77.5 2.0 8e-22 76.9 0.9 1.7 2 0 0 2 2 2 1 Bromodomain Acetyltransf_7 PF13508.1 CBZ52027.1 - 3.2e-11 43.2 1.2 5.9e-11 42.3 0.9 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 CBZ52027.1 - 4.4e-11 42.6 0.3 1.7e-10 40.7 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 CBZ52027.1 - 3.1e-06 27.3 0.0 9.1e-06 25.7 0.0 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 CBZ52027.1 - 0.0021 17.7 0.1 0.0073 16.0 0.0 1.9 1 1 1 2 2 2 1 FR47-like protein Acetyltransf_9 PF13527.1 CBZ52027.1 - 0.0029 17.4 0.0 0.0092 15.8 0.0 1.9 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 CBZ52027.1 - 0.0086 16.2 0.1 0.056 13.6 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain DUF4407 PF14362.1 CBZ52027.1 - 0.11 11.4 1.7 0.19 10.6 1.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) ARL2_Bind_BART PF11527.3 CBZ52027.1 - 0.18 11.6 3.7 0.31 10.8 2.6 1.3 1 0 0 1 1 1 0 The ARF-like 2 binding protein BART Ras PF00071.17 CBZ52028.1 - 7e-52 175.0 0.0 9.7e-52 174.6 0.0 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CBZ52028.1 - 1.5e-17 64.2 0.0 2.4e-17 63.5 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CBZ52028.1 - 2.7e-14 52.7 0.0 4.2e-14 52.1 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 CBZ52028.1 - 1.5e-05 24.4 0.0 3.6e-05 23.2 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 CBZ52028.1 - 4.9e-05 23.2 0.0 8.7e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 CBZ52028.1 - 0.0071 15.5 0.0 0.01 15.0 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 CBZ52028.1 - 0.047 12.9 0.0 0.087 12.0 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit ELL PF10390.4 CBZ52028.1 - 1.5 7.9 5.7 0.4 9.8 1.7 1.7 2 0 0 2 2 2 0 RNA polymerase II elongation factor ELL Macoilin PF09726.4 CBZ52028.1 - 2 6.5 18.5 2.7 6.1 12.8 1.1 1 0 0 1 1 1 0 Transmembrane protein Ribosomal_L3 PF00297.17 CBZ52031.1 - 1.9e-23 83.2 1.3 2.8e-21 76.1 0.7 2.1 2 0 0 2 2 2 2 Ribosomal protein L3 BCS1_N PF08740.6 CBZ52032.1 - 3.6e-42 144.0 0.1 8.4e-42 142.8 0.1 1.6 1 1 0 1 1 1 1 BCS1 N terminal AAA PF00004.24 CBZ52032.1 - 1.2e-16 61.0 0.0 1.8e-15 57.2 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 CBZ52032.1 - 5.7e-05 23.9 0.0 0.0006 20.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 CBZ52032.1 - 0.0012 18.5 0.0 0.0025 17.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 CBZ52032.1 - 0.0016 17.9 0.0 0.0035 16.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 CBZ52032.1 - 0.0028 17.5 0.3 0.0094 15.8 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 CBZ52032.1 - 0.0044 17.0 0.4 0.017 15.1 0.1 2.4 2 1 0 2 2 2 1 AAA ATPase domain PPV_E1_C PF00519.12 CBZ52032.1 - 0.0049 15.5 0.0 0.0073 14.9 0.0 1.1 1 0 0 1 1 1 1 Papillomavirus helicase RuvB_N PF05496.7 CBZ52032.1 - 0.0096 14.9 0.0 0.017 14.1 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus RNA_helicase PF00910.17 CBZ52032.1 - 0.011 15.9 0.0 0.037 14.2 0.0 1.9 2 0 0 2 2 2 0 RNA helicase AAA_22 PF13401.1 CBZ52032.1 - 0.011 15.8 0.0 0.034 14.2 0.0 1.8 2 0 0 2 2 1 0 AAA domain NACHT PF05729.7 CBZ52032.1 - 0.017 14.7 0.0 0.48 10.0 0.0 2.5 2 0 0 2 2 2 0 NACHT domain AAA_18 PF13238.1 CBZ52032.1 - 0.018 15.3 0.0 2.3 8.5 0.0 2.7 3 0 0 3 3 3 0 AAA domain AAA_14 PF13173.1 CBZ52032.1 - 0.034 14.0 0.0 0.07 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.1 CBZ52032.1 - 0.041 13.4 0.0 0.065 12.7 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.1 CBZ52032.1 - 0.043 13.7 0.1 1.2 9.1 0.0 2.7 3 0 0 3 3 3 0 AAA domain ABC_tran PF00005.22 CBZ52032.1 - 0.048 13.9 0.0 0.12 12.6 0.0 1.7 1 0 0 1 1 1 0 ABC transporter KaiC PF06745.8 CBZ52032.1 - 0.06 12.4 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 KaiC AAA_19 PF13245.1 CBZ52032.1 - 0.065 12.9 0.0 0.29 10.9 0.0 2.2 1 0 0 1 1 1 0 Part of AAA domain DUF815 PF05673.8 CBZ52032.1 - 0.078 11.8 0.0 0.17 10.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Rad17 PF03215.10 CBZ52032.1 - 0.15 10.6 0.0 0.23 10.1 0.0 1.1 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein AAA_24 PF13479.1 CBZ52032.1 - 0.19 11.2 0.4 22 4.5 0.1 2.5 2 0 0 2 2 2 0 AAA domain Pkinase PF00069.20 CBZ52033.1 - 4.2e-64 216.2 0.0 6.2e-64 215.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ52033.1 - 5.7e-36 123.9 0.0 1.1e-35 123.0 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBZ52033.1 - 5.6e-08 32.0 0.0 7.9e-08 31.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 CBZ52033.1 - 5e-05 22.7 0.4 8.2e-05 22.0 0.3 1.3 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.9 CBZ52033.1 - 5.9e-05 22.2 0.2 0.00012 21.2 0.1 1.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CBZ52033.1 - 0.042 13.5 0.0 0.099 12.3 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family DCX PF03607.12 CBZ52033.1 - 0.13 11.8 0.1 2.4 7.8 0.0 2.7 3 0 0 3 3 3 0 Doublecortin OTU PF02338.14 CBZ52034.1 - 2.3e-17 63.7 0.2 2.3e-17 63.7 0.1 2.0 2 0 0 2 2 2 1 OTU-like cysteine protease Peptidase_C65 PF10275.4 CBZ52034.1 - 1.5e-07 31.0 0.1 0.00024 20.5 0.0 2.4 1 1 1 2 2 2 2 Peptidase C65 Otubain PPR_2 PF13041.1 CBZ52035.1 - 1e-44 150.2 0.7 1.9e-10 40.5 0.0 8.3 3 2 5 8 8 8 7 PPR repeat family PPR_3 PF13812.1 CBZ52035.1 - 7.3e-28 94.4 9.6 0.00023 21.2 0.1 10.5 10 0 0 10 10 10 5 Pentatricopeptide repeat domain PPR PF01535.15 CBZ52035.1 - 2.4e-26 89.8 8.1 0.0024 17.7 0.0 10.0 11 0 0 11 11 11 6 PPR repeat PPR_1 PF12854.2 CBZ52035.1 - 1.9e-23 81.6 0.0 0.0072 15.7 0.0 8.5 8 0 0 8 8 8 7 PPR repeat TPR_14 PF13428.1 CBZ52035.1 - 1.8e-07 31.1 0.3 0.25 12.0 0.6 5.4 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.1 CBZ52035.1 - 0.00092 19.5 0.1 0.78 10.1 0.1 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat SelB-wing_2 PF09106.6 CBZ52035.1 - 0.024 14.5 0.0 12 5.8 0.0 3.1 2 0 0 2 2 2 0 Elongation factor SelB, winged helix ECSIT PF06239.6 CBZ52035.1 - 0.036 12.9 0.0 12 4.6 0.0 3.6 4 0 0 4 4 4 0 Evolutionarily conserved signalling intermediate in Toll pathway RabGAP-TBC PF00566.13 CBZ52035.1 - 0.095 12.1 0.0 0.27 10.6 0.0 1.7 2 0 0 2 2 2 0 Rab-GTPase-TBC domain WD40 PF00400.27 CBZ52036.1 - 5.3e-54 178.2 8.1 6.5e-09 35.3 0.0 8.4 8 0 0 8 8 8 8 WD domain, G-beta repeat PRP4 PF08799.6 CBZ52036.1 - 3.4e-11 42.2 0.7 3.4e-11 42.2 0.5 3.0 3 0 0 3 3 3 1 pre-mRNA processing factor 4 (PRP4) like Nup160 PF11715.3 CBZ52036.1 - 0.00012 20.4 7.2 0.21 9.7 0.1 4.5 1 1 4 5 5 5 2 Nucleoporin Nup120/160 SHIPPO-rpt PF07004.7 CBZ52037.1 - 1e-22 79.8 37.6 0.00029 21.5 0.2 6.6 6 0 0 6 6 6 6 Sperm-tail PG-rich repeat DUF4496 PF14908.1 CBZ52038.1 - 7.2e-36 123.1 0.0 8.9e-36 122.8 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4496) Bac_DNA_binding PF00216.16 CBZ52038.1 - 0.0025 17.7 0.0 0.051 13.6 0.0 2.3 2 0 0 2 2 2 1 Bacterial DNA-binding protein Peptidase_C23 PF05379.6 CBZ52038.1 - 0.14 12.1 0.0 0.28 11.1 0.0 1.5 1 0 0 1 1 1 0 Carlavirus endopeptidase Ribosomal_S26e PF01283.14 CBZ52039.1 - 7.9e-51 171.1 7.2 9.2e-51 170.8 5.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e SRP19 PF01922.12 CBZ52039.1 - 0.076 13.5 0.6 0.11 13.1 0.4 1.3 1 0 0 1 1 1 0 SRP19 protein Fer4_9 PF13187.1 CBZ52039.1 - 0.27 11.5 4.6 0.57 10.4 3.0 1.6 1 1 0 1 1 1 0 4Fe-4S dicluster domain Fer4_10 PF13237.1 CBZ52039.1 - 0.42 10.4 5.5 0.8 9.5 3.8 1.4 1 1 0 1 1 1 0 4Fe-4S dicluster domain Fer4_7 PF12838.2 CBZ52039.1 - 0.72 10.2 5.0 1.3 9.4 3.4 1.6 1 1 0 1 1 1 0 4Fe-4S dicluster domain Fer4_18 PF13746.1 CBZ52039.1 - 1.9 8.9 6.6 0.58 10.6 0.4 2.3 2 1 0 2 2 2 0 4Fe-4S dicluster domain HIT PF01230.18 CBZ52040.1 - 6.1e-26 90.8 0.0 8.2e-26 90.4 0.0 1.2 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 CBZ52040.1 - 7.4e-11 42.2 0.0 9.9e-11 41.8 0.0 1.1 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding Exo_endo_phos PF03372.18 CBZ52041.1 - 1.6e-13 51.1 0.0 3.2e-13 50.1 0.0 1.5 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Vezatin PF12632.2 CBZ52041.1 - 0.023 13.7 0.4 0.037 13.1 0.3 1.3 1 0 0 1 1 1 0 Mysoin-binding motif of peroxisomes Acetyltransf_1 PF00583.19 CBZ52042.1 - 8e-11 41.8 0.1 1.2e-10 41.2 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 CBZ52042.1 - 1.8e-06 27.5 0.0 3.3e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.1 CBZ52042.1 - 2e-05 24.6 0.0 4.2e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 CBZ52042.1 - 2.8e-05 24.2 0.0 5.8e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 CBZ52042.1 - 4.8e-05 23.1 0.0 9.6e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_3 PF13302.1 CBZ52042.1 - 8.2e-05 22.7 0.0 0.00015 21.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DNA_methylase PF00145.12 CBZ52043.1 - 3.9e-22 78.8 0.5 7.1e-14 51.6 0.0 3.8 4 1 0 4 4 4 2 C-5 cytosine-specific DNA methylase BCAS2 PF05700.6 CBZ52044.1 - 6e-28 97.8 3.0 2.7e-23 82.6 0.4 2.1 1 1 1 2 2 2 2 Breast carcinoma amplified sequence 2 (BCAS2) DUF4631 PF15450.1 CBZ52044.1 - 0.013 13.8 0.3 0.02 13.1 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4631) S4_2 PF13275.1 CBZ52044.1 - 0.31 10.6 1.3 1 8.9 0.1 2.1 2 0 0 2 2 2 0 S4 domain GMC_oxred_C PF05199.8 CBZ52046.1 - 7.9e-16 58.6 0.0 6.3e-13 49.2 0.0 2.6 2 0 0 2 2 2 2 GMC oxidoreductase GMC_oxred_N PF00732.14 CBZ52046.1 - 8.2e-14 51.4 0.0 1.5e-10 40.6 0.0 2.2 2 0 0 2 2 2 2 GMC oxidoreductase DapB_C PF05173.9 CBZ52048.1 - 2.8e-40 137.1 1.0 4.4e-40 136.4 0.7 1.3 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, C-terminus DapB_N PF01113.15 CBZ52048.1 - 1.2e-16 60.7 0.1 7.1e-09 35.6 0.0 2.6 2 0 0 2 2 2 2 Dihydrodipicolinate reductase, N-terminus Cpn60_TCP1 PF00118.19 CBZ52050.1 - 2.1e-124 415.8 4.8 1.8e-92 310.4 0.5 2.0 2 0 0 2 2 2 2 TCP-1/cpn60 chaperonin family PEX11 PF05648.9 CBZ52051.1 - 7.2e-39 133.3 0.8 1.9e-38 131.9 0.6 1.7 1 1 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) AAA_32 PF13654.1 CBZ52051.1 - 0.019 13.6 0.4 0.027 13.1 0.3 1.1 1 0 0 1 1 1 0 AAA domain Cys_rich_VLP PF14194.1 CBZ52051.1 - 0.02 14.5 0.2 0.046 13.4 0.1 1.6 1 0 0 1 1 1 0 Cysteine-rich VLP Acid_PPase PF12689.2 CBZ52052.1 - 0.054 13.1 0.0 0.09 12.4 0.0 1.3 1 0 0 1 1 1 0 Acid Phosphatase WD40 PF00400.27 CBZ52053.1 - 2e-30 103.5 12.7 5.8e-10 38.6 0.6 3.5 3 0 0 3 3 3 3 WD domain, G-beta repeat DUF3829 PF12889.2 CBZ52053.1 - 0.02 14.0 4.6 1.3 8.1 0.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3829) Matrilin_ccoil PF10393.4 CBZ52053.1 - 0.024 14.0 0.3 0.056 12.8 0.2 1.6 1 0 0 1 1 1 0 Trimeric coiled-coil oligomerisation domain of matrilin APG6 PF04111.7 CBZ52053.1 - 0.17 10.9 18.8 0.11 11.4 3.2 2.1 1 1 0 2 2 2 0 Autophagy protein Apg6 DUF812 PF05667.6 CBZ52053.1 - 0.29 9.5 13.5 0.7 8.3 9.1 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF812) V_ATPase_I PF01496.14 CBZ52053.1 - 1.2 6.9 9.3 1.6 6.4 6.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Syntaxin PF00804.20 CBZ52053.1 - 1.9 8.7 7.2 2 8.6 0.8 2.4 2 0 0 2 2 2 0 Syntaxin DUF4446 PF14584.1 CBZ52053.1 - 1.9 8.3 4.2 0.91 9.3 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) IncA PF04156.9 CBZ52053.1 - 1.9 8.0 16.2 96 2.4 11.2 2.6 1 1 0 1 1 1 0 IncA protein TPR_MLP1_2 PF07926.7 CBZ52053.1 - 2 8.1 12.9 0.18 11.5 1.2 2.8 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein Bap31 PF05529.7 CBZ52053.1 - 2.6 7.4 8.9 0.12 11.7 0.4 2.3 2 1 0 2 2 2 0 B-cell receptor-associated protein 31-like Vfa1 PF08432.5 CBZ52053.1 - 2.8 7.9 11.4 3.6 7.5 0.5 2.5 1 1 1 2 2 2 0 AAA-ATPase Vps4-associated protein 1 TMF_TATA_bd PF12325.3 CBZ52053.1 - 3.9 7.2 14.9 2.7 7.7 1.5 2.6 2 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF4200 PF13863.1 CBZ52053.1 - 4.1 7.3 16.1 0.18 11.7 4.1 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4200) EAP30 PF04157.11 CBZ52053.1 - 5 6.2 6.8 1.8 7.6 1.0 2.1 2 0 0 2 2 2 0 EAP30/Vps36 family Seryl_tRNA_N PF02403.17 CBZ52053.1 - 8.9 6.3 12.5 1.5 8.8 1.0 2.8 2 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain TRAM_LAG1_CLN8 PF03798.11 CBZ52056.1 - 6e-15 55.3 15.3 6e-15 55.3 10.6 1.9 2 0 0 2 2 2 1 TLC domain 7tm_1 PF00001.16 CBZ52057.1 - 0.0019 17.4 0.2 0.0026 16.9 0.1 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Plasmodium_Vir PF05795.6 CBZ52057.1 - 0.085 12.0 0.0 0.11 11.7 0.0 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Cbl_N PF02262.11 CBZ52058.1 - 0.12 12.0 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 CBL proto-oncogene N-terminal domain 1 SAG PF04092.8 CBZ52059.1 - 0.0009 19.6 0.1 0.0014 19.0 0.0 1.3 1 0 0 1 1 1 1 SRS domain TOBE PF03459.12 CBZ52059.1 - 0.082 13.0 0.4 4.7 7.4 0.0 2.3 2 0 0 2 2 2 0 TOBE domain AMP-binding PF00501.23 CBZ52060.1 - 1.6e-72 244.2 0.0 3.9e-72 242.9 0.0 1.6 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 CBZ52060.1 - 0.0012 19.6 1.0 0.013 16.3 0.1 2.4 1 1 1 2 2 2 1 AMP-binding enzyme C-terminal domain DUF2201_N PF13203.1 CBZ52060.1 - 0.011 14.8 5.1 0.018 14.2 3.5 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain DUF1510 PF07423.6 CBZ52060.1 - 3.1 7.1 14.0 4.7 6.5 9.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Hydrolase_3 PF08282.7 CBZ52061.1 - 1.3e-52 178.9 0.0 1.5e-52 178.7 0.0 1.0 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.8 CBZ52061.1 - 7.5e-11 41.8 0.0 2.1e-06 27.2 0.0 2.4 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase Hydrolase PF00702.21 CBZ52061.1 - 1.1e-07 32.5 0.1 4e-07 30.6 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.1 CBZ52061.1 - 0.00078 19.2 0.0 0.076 12.9 0.0 2.9 3 0 0 3 3 3 1 Haloacid dehalogenase-like hydrolase HAD PF12710.2 CBZ52061.1 - 0.00091 19.4 0.7 0.074 13.2 0.5 3.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase VirD1 PF07328.6 CBZ52061.1 - 0.072 12.8 0.6 1.4 8.7 0.1 2.2 2 0 0 2 2 2 0 T-DNA border endonuclease VirD1 HAD_2 PF13419.1 CBZ52061.1 - 0.099 12.8 0.0 11 6.2 0.0 3.1 3 0 0 3 3 3 0 Haloacid dehalogenase-like hydrolase MCM PF00493.18 CBZ52062.1 - 3e-127 424.0 0.0 4e-127 423.5 0.0 1.1 1 0 0 1 1 1 1 MCM2/3/5 family Mg_chelatase PF01078.16 CBZ52062.1 - 5.9e-08 32.1 0.1 8.2e-06 25.1 0.0 2.7 3 0 0 3 3 3 2 Magnesium chelatase, subunit ChlI MCM_N PF14551.1 CBZ52062.1 - 8e-06 26.3 0.0 2.2e-05 24.9 0.0 1.8 1 0 0 1 1 1 1 MCM N-terminal domain AAA_5 PF07728.9 CBZ52062.1 - 0.002 17.8 0.0 0.0091 15.7 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 CBZ52062.1 - 0.0033 17.0 0.0 0.013 15.1 0.0 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 CBZ52062.1 - 0.022 14.2 0.0 0.18 11.2 0.0 2.2 1 1 0 1 1 1 0 Sigma-54 interaction domain Prominin PF05478.6 CBZ52064.1 - 0.0028 15.2 0.7 0.0043 14.6 0.5 1.3 1 1 0 1 1 1 1 Prominin RNase_E_G PF10150.4 CBZ52064.1 - 0.015 14.4 0.6 0.018 14.3 0.4 1.1 1 0 0 1 1 1 0 Ribonuclease E/G family BRI3BP PF14965.1 CBZ52064.1 - 0.023 14.0 0.3 0.53 9.6 0.0 2.2 1 1 1 2 2 2 0 Negative regulator of p53/TP53 PDGLE PF13190.1 CBZ52064.1 - 0.036 13.7 2.9 2.5 7.8 0.1 2.2 2 0 0 2 2 2 0 PDGLE domain DUF3373 PF11853.3 CBZ52064.1 - 0.057 11.9 1.1 0.052 12.0 0.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) DinB_2 PF12867.2 CBZ52064.1 - 0.081 13.2 1.4 11 6.3 0.6 2.3 1 1 1 2 2 2 0 DinB superfamily AAA_13 PF13166.1 CBZ52064.1 - 0.13 10.6 5.6 0.15 10.4 3.9 1.0 1 0 0 1 1 1 0 AAA domain IncA PF04156.9 CBZ52064.1 - 0.13 11.8 10.0 0.19 11.3 7.0 1.2 1 0 0 1 1 1 0 IncA protein DUF2611 PF11022.3 CBZ52064.1 - 0.14 12.2 1.0 2.3 8.3 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2611) Baculo_PEP_C PF04513.7 CBZ52064.1 - 0.18 11.6 6.0 1.3 8.8 3.6 2.0 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Apolipoprotein PF01442.13 CBZ52064.1 - 0.26 10.7 11.1 0.5 9.8 7.7 1.5 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain FdhE PF04216.7 CBZ52064.1 - 0.35 10.5 4.9 0.43 10.2 3.4 1.1 1 0 0 1 1 1 0 Protein involved in formate dehydrogenase formation Fmp27_WPPW PF10359.4 CBZ52064.1 - 0.5 8.7 4.3 0.57 8.5 3.0 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain TBPIP PF07106.8 CBZ52064.1 - 0.82 9.1 10.6 0.87 9.1 0.3 2.0 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) CRISPR_Cse1 PF09481.5 CBZ52064.1 - 0.83 8.3 3.8 8.9 4.9 2.7 1.9 1 1 0 1 1 1 0 CRISPR-associated protein Cse1 (CRISPR_cse1) ROS_MUCR PF05443.6 CBZ52064.1 - 1.5 8.5 4.0 1.2 8.8 0.1 2.4 2 1 0 2 2 2 0 ROS/MUCR transcriptional regulator protein Syntaxin-6_N PF09177.6 CBZ52064.1 - 1.8 8.9 7.7 4.7 7.6 2.3 2.5 1 1 0 2 2 2 0 Syntaxin 6, N-terminal DivIVA PF05103.8 CBZ52064.1 - 2.1 8.3 9.9 1.3 9.0 4.5 2.0 1 1 1 2 2 2 0 DivIVA protein Mnd1 PF03962.10 CBZ52064.1 - 3.1 7.4 9.5 2.5 7.7 5.6 1.5 1 1 0 1 1 1 0 Mnd1 family FlxA PF14282.1 CBZ52064.1 - 3.6 7.5 12.4 1.2 9.1 6.0 2.0 1 1 1 2 2 2 0 FlxA-like protein DUF1451 PF07295.6 CBZ52064.1 - 3.7 7.3 7.8 6.1 6.6 4.8 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1451) DUF883 PF05957.8 CBZ52064.1 - 3.7 7.9 9.1 9.4 6.7 0.8 2.7 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF883) TPR_MLP1_2 PF07926.7 CBZ52064.1 - 3.9 7.2 13.4 0.89 9.2 3.7 2.8 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Laminin_II PF06009.7 CBZ52064.1 - 4.1 7.1 8.4 5.9 6.6 3.9 2.0 1 1 1 2 2 2 0 Laminin Domain II LUC7 PF03194.10 CBZ52064.1 - 4.3 6.8 7.8 61 3.0 5.4 2.0 1 1 0 1 1 1 0 LUC7 N_terminus MxiH PF09392.5 CBZ52064.1 - 6.3 7.4 11.1 5.5e+02 1.2 7.7 2.3 1 1 0 1 1 1 0 Type III secretion needle MxiH like PEP-utilisers_N PF05524.8 CBZ52064.1 - 9.8 5.9 9.2 4.1 7.2 4.0 1.8 1 1 1 2 2 2 0 PEP-utilising enzyme, N-terminal Band_7 PF01145.20 CBZ52065.1 - 6.9e-28 97.7 0.7 1.3e-26 93.6 0.1 2.0 1 1 1 2 2 2 1 SPFH domain / Band 7 family BMC PF00936.14 CBZ52065.1 - 0.1 12.3 0.5 0.2 11.3 0.0 1.7 2 0 0 2 2 2 0 BMC domain Med2 PF11214.3 CBZ52065.1 - 0.1 12.6 0.6 0.19 11.7 0.4 1.4 1 0 0 1 1 1 0 Mediator complex subunit 2 NTF2 PF02136.15 CBZ52066.1 - 7e-15 55.4 0.1 1.3e-14 54.6 0.1 1.5 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain HR1 PF02185.11 CBZ52068.1 - 0.0054 16.4 0.8 0.0098 15.6 0.6 1.4 1 0 0 1 1 1 1 Hr1 repeat Peptidase_C14 PF00656.17 CBZ52068.1 - 0.011 15.3 0.1 0.012 15.2 0.0 1.0 1 0 0 1 1 1 0 Caspase domain TMF_TATA_bd PF12325.3 CBZ52068.1 - 0.012 15.3 1.1 0.016 14.8 0.8 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding Spc7 PF08317.6 CBZ52068.1 - 0.016 13.9 0.9 0.02 13.5 0.6 1.0 1 0 0 1 1 1 0 Spc7 kinetochore protein TMF_DNA_bd PF12329.3 CBZ52068.1 - 0.044 13.5 1.1 0.044 13.5 0.8 2.0 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding FlxA PF14282.1 CBZ52068.1 - 0.052 13.5 0.3 0.072 13.0 0.2 1.3 1 0 0 1 1 1 0 FlxA-like protein DUF3340 PF11818.3 CBZ52068.1 - 0.086 12.7 0.7 0.12 12.2 0.5 1.3 1 0 0 1 1 1 0 C-terminal domain of tail specific protease (DUF3340) L27_2 PF09045.5 CBZ52068.1 - 0.16 11.5 4.8 2.7 7.6 0.9 2.4 1 1 0 2 2 2 0 L27_2 Sec2p PF06428.6 CBZ52068.1 - 0.24 11.2 2.8 0.65 9.8 1.3 1.9 1 1 1 2 2 2 0 GDP/GTP exchange factor Sec2p NIF PF03031.13 CBZ52069.1 - 6e-38 130.0 0.0 8.6e-38 129.5 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase HAD_2 PF13419.1 CBZ52069.1 - 0.047 13.8 0.0 0.094 12.9 0.0 1.5 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase DEAD PF00270.24 CBZ52070.1 - 1.2e-42 145.2 0.0 2.7e-42 144.1 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CBZ52070.1 - 1.4e-15 56.8 1.4 1.3e-06 28.2 0.0 3.2 3 0 0 3 3 3 2 Helicase conserved C-terminal domain DUF4217 PF13959.1 CBZ52070.1 - 3.5e-12 45.6 0.0 7.8e-12 44.5 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.10 CBZ52070.1 - 0.00013 21.8 0.1 0.00053 19.8 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit HORMA PF02301.13 CBZ52071.1 - 1.6e-10 40.7 0.0 3.2e-10 39.8 0.0 1.5 1 0 0 1 1 1 1 HORMA domain AHSA1 PF08327.6 CBZ52072.1 - 3.5e-16 59.4 0.1 5.8e-16 58.7 0.1 1.4 1 1 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein Cloacin_immun PF03513.9 CBZ52072.1 - 0.013 15.4 0.0 0.026 14.5 0.0 1.5 1 0 0 1 1 1 0 Cloacin immunity protein CENP-F_leu_zip PF10473.4 CBZ52073.1 - 3.5 7.4 117.4 0.019 14.8 19.3 7.1 1 1 4 6 6 6 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Tetraspannin PF00335.15 CBZ52074.1 - 0.0017 17.6 0.2 0.0017 17.6 0.1 1.8 2 0 0 2 2 2 1 Tetraspanin family Vac14_Fab1_bd PF12755.2 CBZ52075.1 - 3.7e-41 139.4 0.5 1e-36 125.1 0.0 3.2 4 0 0 4 4 4 2 Vacuolar 14 Fab1-binding region Vac14_Fig4_bd PF11916.3 CBZ52075.1 - 2e-40 137.9 5.2 3.3e-37 127.3 2.4 2.3 2 0 0 2 2 2 2 Vacuolar protein 14 C-terminal Fig4p binding HEAT PF02985.17 CBZ52075.1 - 5.1e-07 29.2 6.9 3.3e-05 23.5 0.0 5.6 6 0 0 6 6 6 1 HEAT repeat HEAT_EZ PF13513.1 CBZ52075.1 - 5.8e-06 26.6 7.1 0.0018 18.7 0.0 4.7 4 0 0 4 4 4 2 HEAT-like repeat HEAT_2 PF13646.1 CBZ52075.1 - 0.00076 19.7 3.2 0.026 14.7 0.0 4.1 3 1 0 3 3 3 1 HEAT repeats Cnd1 PF12717.2 CBZ52075.1 - 0.0034 17.2 0.6 34 4.2 0.0 4.2 4 0 0 4 4 4 0 non-SMC mitotic condensation complex subunit 1 DUF2454 PF10521.4 CBZ52075.1 - 0.0037 16.2 0.2 0.054 12.5 0.0 2.6 3 0 0 3 3 3 1 Protein of unknown function (DUF2454) PPR_2 PF13041.1 CBZ52076.1 - 8.1e-11 41.7 0.0 0.0018 18.1 0.0 5.4 5 0 0 5 5 5 2 PPR repeat family PPR PF01535.15 CBZ52076.1 - 1.2e-09 37.4 0.2 0.3 11.1 0.0 6.4 6 0 0 6 6 6 2 PPR repeat PPR_3 PF13812.1 CBZ52076.1 - 0.0028 17.8 16.5 2.8 8.4 0.0 7.5 8 0 0 8 8 8 1 Pentatricopeptide repeat domain TPR_10 PF13374.1 CBZ52076.1 - 0.0093 15.8 0.3 0.0093 15.8 0.2 6.9 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_12 PF13424.1 CBZ52076.1 - 0.016 15.1 9.8 0.26 11.2 0.0 5.4 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_7 PF13176.1 CBZ52076.1 - 0.035 13.9 0.4 0.035 13.9 0.3 5.4 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_8 PF13181.1 CBZ52076.1 - 0.049 13.4 0.1 0.17 11.7 0.0 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat Ank_2 PF12796.2 CBZ52077.1 - 9.5e-18 64.3 0.3 2.5e-10 40.5 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 CBZ52077.1 - 9.2e-17 59.9 2.2 3.4e-05 23.4 0.0 4.8 4 0 0 4 4 4 4 Ankyrin repeat Ank_3 PF13606.1 CBZ52077.1 - 2.3e-11 42.7 0.1 0.31 11.3 0.0 5.2 5 0 0 5 5 5 3 Ankyrin repeat Ank_4 PF13637.1 CBZ52077.1 - 4.2e-11 43.0 0.1 0.00038 20.8 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 CBZ52077.1 - 1.2e-07 31.6 1.9 0.16 12.2 0.0 3.9 2 2 2 4 4 4 2 Ankyrin repeats (many copies) Med3 PF11593.3 CBZ52077.1 - 1.3 8.1 8.5 2.7 7.1 5.9 1.4 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Carb_anhydrase PF00194.16 CBZ52078.1 - 0.077 11.9 0.0 0.8 8.6 0.0 2.2 2 1 0 2 2 2 0 Eukaryotic-type carbonic anhydrase Prp31_C PF09785.4 CBZ52080.1 - 7.3e-52 175.0 11.6 1.1e-30 106.6 4.1 5.8 5 0 0 5 5 5 5 Prp31 C terminal domain Nop PF01798.13 CBZ52080.1 - 1.7e-31 108.5 1.5 1.7e-31 108.5 1.1 1.7 2 0 0 2 2 2 1 Putative snoRNA binding domain NOSIC PF08060.8 CBZ52080.1 - 1.5e-16 59.9 0.4 2.7e-16 59.1 0.3 1.4 1 0 0 1 1 1 1 NOSIC (NUC001) domain HATPase_c PF02518.21 CBZ52080.1 - 6.8e-06 25.7 0.0 11 5.7 0.0 4.5 4 0 0 4 4 4 3 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase BCHF PF07284.6 CBZ52080.1 - 0.00087 19.1 0.2 20 5.0 0.0 4.1 4 0 0 4 4 4 1 2-vinyl bacteriochlorophyllide hydratase (BCHF) DUF4203 PF13886.1 CBZ52080.1 - 0.077 12.4 1.2 18 4.7 0.0 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4203) NAP PF00956.13 CBZ52081.1 - 6.5e-68 228.4 7.3 6.5e-68 228.4 5.1 1.8 2 0 0 2 2 2 1 Nucleosome assembly protein (NAP) zf-CW PF07496.10 CBZ52082.1 - 2.8e-06 26.9 9.1 8.4e-06 25.3 6.3 1.9 1 0 0 1 1 1 1 CW-type Zinc Finger PrmA PF06325.8 CBZ52082.1 - 0.0058 15.8 0.0 0.0093 15.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_3 PF01596.12 CBZ52082.1 - 0.56 9.2 0.0 0.96 8.4 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase UPF0081 PF03652.10 CBZ52084.1 - 3e-07 30.6 0.0 0.0035 17.4 0.0 3.4 3 0 0 3 3 3 3 Uncharacterised protein family (UPF0081) TFIID_20kDa PF03847.8 CBZ52086.1 - 0.025 14.8 0.0 0.039 14.2 0.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A PT PF04886.7 CBZ52086.1 - 0.086 12.1 9.0 8.5 5.7 6.2 2.9 1 1 0 1 1 1 0 PT repeat cEGF PF12662.2 CBZ52088.1 - 3.1e-07 29.8 89.6 0.012 15.1 3.2 10.6 11 0 0 11 11 11 8 Complement Clr-like EGF-like EGF_3 PF12947.2 CBZ52088.1 - 8.6e-05 22.4 109.9 0.0048 16.8 7.7 11.2 10 1 0 10 10 10 5 EGF domain EGF_MSP1_1 PF12946.2 CBZ52088.1 - 0.0025 17.5 3.7 0.0025 17.5 2.6 10.3 10 0 0 10 10 10 3 MSP1 EGF domain 1 FXa_inhibition PF14670.1 CBZ52088.1 - 0.0079 16.3 3.7 0.0079 16.3 2.6 11.4 9 2 2 11 11 11 6 Coagulation Factor Xa inhibitory site DUF3991 PF13154.1 CBZ52088.1 - 0.011 15.8 0.1 0.024 14.7 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3991) DUF4244 PF14029.1 CBZ52089.1 - 0.014 14.4 0.1 0.025 13.6 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4244) Transket_pyr PF02779.19 CBZ52090.1 - 4.5e-61 205.4 0.0 7.9e-61 204.6 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.15 CBZ52090.1 - 7.2e-54 182.5 0.0 1.1e-53 181.8 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component Plus-3 PF03126.13 CBZ52091.1 - 1.8e-06 27.9 0.0 5.1e-06 26.4 0.0 1.7 1 1 0 1 1 1 1 Plus-3 domain NPV_P10 PF05531.7 CBZ52091.1 - 0.03 14.5 2.8 2.1 8.6 0.3 2.4 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Rhomboid PF01694.17 CBZ52092.1 - 2e-05 24.6 1.7 0.0031 17.5 0.0 2.9 3 0 0 3 3 3 2 Rhomboid family DUF1275 PF06912.6 CBZ52092.1 - 0.27 10.4 3.8 0.19 10.8 0.1 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF1275) Methyltransf_26 PF13659.1 CBZ52093.1 - 5.6e-12 45.7 0.0 9.9e-12 44.9 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 CBZ52093.1 - 0.0066 15.8 0.0 0.044 13.1 0.0 2.2 3 0 0 3 3 3 1 Methyltransferase small domain LRS4 PF10422.4 CBZ52095.1 - 0.0059 15.9 0.2 0.006 15.9 0.1 1.1 1 0 0 1 1 1 1 Monopolin complex subunit LRS4 DUF2968 PF11180.3 CBZ52095.1 - 0.026 13.8 0.1 0.039 13.3 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) DUF1465 PF07323.7 CBZ52095.1 - 0.031 13.8 0.1 0.042 13.4 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1465) DUF904 PF06005.7 CBZ52095.1 - 0.14 12.5 0.8 0.32 11.3 0.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF904) ABC_tran PF00005.22 CBZ52096.1 - 1.5e-22 80.3 0.0 2.6e-22 79.6 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC2_membrane PF01061.19 CBZ52096.1 - 1.5e-21 76.5 24.2 2.3e-21 75.9 16.8 1.3 1 0 0 1 1 1 1 ABC-2 type transporter AAA_17 PF13207.1 CBZ52096.1 - 9.1e-05 23.2 0.0 0.0002 22.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain ABC2_membrane_3 PF12698.2 CBZ52096.1 - 9.4e-05 21.5 23.6 0.00013 21.0 16.4 1.2 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_25 PF13481.1 CBZ52096.1 - 0.00012 21.5 0.0 0.00033 20.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.1 CBZ52096.1 - 0.0014 18.0 0.1 0.004 16.6 0.1 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.1 CBZ52096.1 - 0.0022 18.1 0.0 0.0044 17.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain MobB PF03205.9 CBZ52096.1 - 0.0057 16.3 0.1 0.01 15.5 0.0 1.4 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_21 PF13304.1 CBZ52096.1 - 0.0076 16.2 0.0 0.05 13.5 0.2 2.0 1 1 1 2 2 2 1 AAA domain AAA_18 PF13238.1 CBZ52096.1 - 0.0079 16.5 0.0 0.015 15.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain RecA PF00154.16 CBZ52096.1 - 0.0079 15.2 0.0 0.013 14.5 0.0 1.2 1 0 0 1 1 1 1 recA bacterial DNA recombination protein AAA_16 PF13191.1 CBZ52096.1 - 0.0092 15.9 2.5 0.013 15.4 0.1 2.3 2 1 0 2 2 2 1 AAA ATPase domain Arch_ATPase PF01637.13 CBZ52096.1 - 0.0099 15.5 0.0 0.016 14.8 0.0 1.2 1 0 0 1 1 1 1 Archaeal ATPase AAA_28 PF13521.1 CBZ52096.1 - 0.025 14.5 0.0 0.055 13.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.1 CBZ52096.1 - 0.027 14.7 0.1 0.056 13.7 0.1 1.4 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.17 CBZ52096.1 - 0.029 13.2 0.0 0.047 12.5 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain ArgK PF03308.11 CBZ52096.1 - 0.039 12.7 0.0 0.077 11.7 0.0 1.4 1 0 0 1 1 1 0 ArgK protein AAA_33 PF13671.1 CBZ52096.1 - 0.062 13.1 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF258 PF03193.11 CBZ52096.1 - 0.078 12.1 0.0 0.14 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 NACHT PF05729.7 CBZ52096.1 - 0.096 12.3 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 NACHT domain cobW PF02492.14 CBZ52096.1 - 0.12 11.8 0.1 0.19 11.1 0.1 1.2 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain KaiC PF06745.8 CBZ52096.1 - 0.17 11.0 0.0 0.28 10.2 0.0 1.3 1 0 0 1 1 1 0 KaiC AAA_14 PF13173.1 CBZ52096.1 - 0.17 11.8 0.0 0.32 10.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.4 CBZ52096.1 - 0.26 10.7 0.0 0.45 10.0 0.0 1.3 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Adaptin_N PF01602.15 CBZ52097.1 - 2.2e-76 257.2 9.4 2.9e-70 237.1 7.9 2.3 2 1 0 2 2 2 2 Adaptin N terminal region AP4E_app_platf PF14807.1 CBZ52097.1 - 9.5e-08 32.2 0.0 2.9e-07 30.6 0.0 1.9 1 0 0 1 1 1 1 Adaptin AP4 complex epsilon appendage platform HEAT_2 PF13646.1 CBZ52097.1 - 0.0001 22.5 13.9 0.0044 17.2 1.6 4.9 4 1 1 5 5 5 2 HEAT repeats HEAT_EZ PF13513.1 CBZ52097.1 - 0.0072 16.7 5.2 0.096 13.2 0.2 4.0 3 0 0 3 3 3 1 HEAT-like repeat Cnd1 PF12717.2 CBZ52097.1 - 0.019 14.8 3.0 3.1 7.5 0.0 3.4 3 0 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 NUC130_3NT PF08158.7 CBZ52097.1 - 0.074 13.3 3.5 4.8 7.5 0.1 3.4 3 0 0 3 3 3 0 NUC130/3NT domain HEAT PF02985.17 CBZ52097.1 - 0.13 12.4 6.0 0.17 12.0 0.0 3.9 4 0 0 4 4 4 0 HEAT repeat ParcG PF10274.4 CBZ52097.1 - 1.4 8.7 7.8 5.6 6.8 0.0 3.6 4 1 0 4 4 4 0 Parkin co-regulated protein MMR_HSR1 PF01926.18 CBZ52099.1 - 1.4e-19 70.1 0.1 3.8e-19 68.7 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase TGS PF02824.16 CBZ52099.1 - 2e-19 69.1 0.1 3.9e-19 68.2 0.1 1.5 1 0 0 1 1 1 1 TGS domain FeoB_N PF02421.13 CBZ52099.1 - 1.3e-11 43.9 0.2 4.6e-11 42.2 0.0 1.9 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.18 CBZ52099.1 - 2.5e-05 24.1 0.2 0.13 12.0 0.0 2.4 1 1 1 2 2 2 2 Dynamin family ArgK PF03308.11 CBZ52099.1 - 0.00027 19.8 0.3 0.0019 17.0 0.1 2.1 2 0 0 2 2 2 1 ArgK protein Miro PF08477.8 CBZ52099.1 - 0.0019 18.7 0.1 0.0051 17.2 0.0 1.8 2 0 0 2 2 2 1 Miro-like protein GTP_EFTU PF00009.22 CBZ52099.1 - 0.0044 16.4 0.3 1.7 8.0 0.0 3.5 2 2 0 2 2 2 1 Elongation factor Tu GTP binding domain AIG1 PF04548.11 CBZ52099.1 - 0.011 14.8 0.0 0.017 14.1 0.0 1.3 1 0 0 1 1 1 0 AIG1 family SRPRB PF09439.5 CBZ52099.1 - 0.087 12.0 0.0 0.16 11.1 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Ribosomal_L24e PF01246.15 CBZ52100.1 - 1.7e-19 69.4 1.0 1.7e-19 69.4 0.7 1.7 2 0 0 2 2 2 1 Ribosomal protein L24e DUF775 PF05603.7 CBZ52100.1 - 0.036 13.6 1.2 0.041 13.4 0.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF775) DUF3740 PF12548.3 CBZ52100.1 - 0.038 14.2 2.8 0.057 13.6 1.9 1.2 1 0 0 1 1 1 0 Sulfatase protein DnaJ PF00226.26 CBZ52102.1 - 1.3e-17 63.2 0.3 3.1e-17 62.0 0.0 1.8 2 0 0 2 2 2 1 DnaJ domain DUF3395 PF11875.3 CBZ52102.1 - 3.7e-13 49.3 0.0 6.9e-09 35.5 0.0 2.4 1 1 1 2 2 2 2 Domain of unknown function (DUF3395) OHA PF14418.1 CBZ52103.1 - 4.1e-24 83.8 0.0 7e-24 83.1 0.0 1.4 1 0 0 1 1 1 1 OST-HTH Associated domain SNARE_assoc PF09335.6 CBZ52104.1 - 4.9e-11 42.9 2.0 2.9e-10 40.4 0.9 2.2 2 1 0 2 2 2 1 SNARE associated Golgi protein Ctr PF04145.10 CBZ52104.1 - 0.003 17.6 0.0 0.0084 16.1 0.0 1.7 1 0 0 1 1 1 1 Ctr copper transporter family UPF0118 PF01594.11 CBZ52104.1 - 0.035 13.0 3.8 0.81 8.6 0.2 2.5 2 1 0 2 2 2 0 Domain of unknown function DUF20 Ta0938 PF11494.3 CBZ52104.1 - 0.062 13.4 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 Ta0938 CactinC_cactus PF09732.4 CBZ52105.1 - 1.3e-53 179.8 7.1 2.6e-53 178.8 4.9 1.5 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein Cactin_mid PF10312.4 CBZ52105.1 - 6.4e-36 123.4 3.0 2.3e-35 121.6 2.0 2.0 1 1 0 1 1 1 1 Conserved mid region of cactin SUFU_C PF12470.3 CBZ52105.1 - 0.0037 16.9 1.8 0.0037 16.9 1.3 2.2 3 0 0 3 3 3 1 Suppressor of Fused Gli/Ci N terminal binding domain Coatomer_E PF04733.9 CBZ52106.1 - 4.7e-24 85.0 5.7 3.7e-17 62.4 1.3 2.0 1 1 1 2 2 2 2 Coatomer epsilon subunit TPR_19 PF14559.1 CBZ52106.1 - 0.0017 18.6 7.8 0.025 14.8 0.0 2.9 2 1 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.23 CBZ52106.1 - 0.0025 17.3 0.8 11 5.8 0.1 3.9 3 0 0 3 3 3 1 Tetratricopeptide repeat Peptidase_M48 PF01435.13 CBZ52106.1 - 0.033 13.7 1.0 0.049 13.1 0.7 1.3 1 0 0 1 1 1 0 Peptidase family M48 Death PF00531.17 CBZ52106.1 - 0.074 12.8 0.4 0.31 10.8 0.1 2.4 2 1 0 2 2 2 0 Death domain TPR_11 PF13414.1 CBZ52106.1 - 0.085 12.5 5.4 0.096 12.3 0.2 2.9 1 1 1 3 3 3 0 TPR repeat TPR_2 PF07719.12 CBZ52106.1 - 0.79 9.7 7.7 12 6.1 0.2 4.0 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.1 CBZ52106.1 - 3.6 8.3 0.0 3.6 8.3 0.0 3.8 4 1 1 5 5 5 0 Tetratricopeptide repeat DUF3633 PF12315.3 CBZ52107.1 - 1.9e-19 69.7 0.6 9.6e-19 67.5 0.4 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF3633) Peptidase_MA_2 PF13485.1 CBZ52107.1 - 0.046 13.7 0.0 0.12 12.4 0.0 1.7 1 0 0 1 1 1 0 Peptidase MA superfamily Pyridoxal_deC PF00282.14 CBZ52108.1 - 1.4e-08 33.6 0.0 2.5e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain DUF947 PF06102.7 CBZ52109.1 - 8e-27 94.1 16.6 1.5e-25 89.9 7.6 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF947) DUF4407 PF14362.1 CBZ52109.1 - 2.5 7.0 7.9 4.9 6.0 5.5 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) PseudoU_synth_2 PF00849.17 CBZ52110.1 - 1.2e-11 44.6 0.1 1.4e-10 41.2 0.1 2.0 1 1 0 1 1 1 1 RNA pseudouridylate synthase Nucleoside_tran PF01733.13 CBZ52111.1 - 2.8e-17 62.8 2.8 2.8e-17 62.8 1.9 2.1 2 0 0 2 2 2 1 Nucleoside transporter PP2C PF00481.16 CBZ52112.1 - 2.5e-34 118.8 0.0 7.2e-32 110.7 0.0 2.7 2 0 0 2 2 2 2 Protein phosphatase 2C La PF05383.12 CBZ52113.1 - 0.027 14.2 0.0 0.041 13.6 0.0 1.3 1 0 0 1 1 1 0 La domain Peptidase_M16 PF00675.15 CBZ52115.1 - 8e-36 123.0 0.0 2.6e-35 121.3 0.0 2.0 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 CBZ52115.1 - 5.3e-26 91.4 0.0 2.3e-20 73.0 0.0 3.4 2 1 1 3 3 3 2 Peptidase M16 inactive domain TTL PF03133.10 CBZ52116.1 - 1.9e-54 184.5 0.5 3e-54 183.9 0.3 1.2 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.1 CBZ52116.1 - 5.5e-07 28.6 0.0 6.5e-05 21.8 0.0 2.9 2 1 1 3 3 3 2 YheC/D like ATP-grasp Glycos_transf_4 PF00953.16 CBZ52118.1 - 1.8e-29 102.5 14.5 3e-24 85.6 5.4 3.3 4 0 0 4 4 4 2 Glycosyl transferase family 4 DUF4366 PF14283.1 CBZ52119.1 - 0.0037 16.7 0.1 0.0097 15.3 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4366) Mito_carr PF00153.22 CBZ52120.1 - 4.4e-12 45.5 0.4 4.6e-07 29.4 0.0 3.7 3 1 1 4 4 4 2 Mitochondrial carrier protein HSP90 PF00183.13 CBZ52122.1 - 7.2e-178 592.2 41.8 7.2e-178 592.2 29.0 2.0 1 1 1 2 2 2 1 Hsp90 protein HATPase_c_3 PF13589.1 CBZ52122.1 - 5.6e-13 48.7 0.1 5.6e-13 48.7 0.0 2.6 3 0 0 3 3 3 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 CBZ52122.1 - 8.8e-11 41.5 0.1 2e-10 40.3 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Ribosomal_L1 PF00687.16 CBZ52124.1 - 2.6e-27 95.5 0.0 6.3e-25 87.8 0.0 2.2 2 0 0 2 2 2 2 Ribosomal protein L1p/L10e family SDA1 PF05285.7 CBZ52124.1 - 0.0059 15.9 5.0 0.49 9.6 2.7 2.1 2 0 0 2 2 2 2 SDA1 Daxx PF03344.10 CBZ52124.1 - 0.81 8.0 10.8 0.03 12.8 3.4 1.5 2 0 0 2 2 2 0 Daxx Family AAA PF00004.24 CBZ52125.1 - 8.1e-38 129.6 0.0 1.3e-37 128.8 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 CBZ52125.1 - 3.7e-07 29.9 0.0 7.5e-06 25.7 0.0 2.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 CBZ52125.1 - 3.9e-05 23.8 0.1 0.0051 16.9 0.0 2.6 1 1 1 2 2 2 1 AAA domain Vps4_C PF09336.5 CBZ52125.1 - 5.2e-05 23.0 0.0 0.00019 21.2 0.0 2.0 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain AAA_19 PF13245.1 CBZ52125.1 - 0.00052 19.7 0.0 0.0021 17.7 0.0 2.0 2 0 0 2 2 1 1 Part of AAA domain AAA_17 PF13207.1 CBZ52125.1 - 0.00083 20.1 0.0 0.0037 18.0 0.0 2.2 2 1 1 3 3 1 1 AAA domain IstB_IS21 PF01695.12 CBZ52125.1 - 0.00096 18.6 0.0 0.0083 15.5 0.0 2.2 2 0 0 2 2 2 1 IstB-like ATP binding protein RuvB_N PF05496.7 CBZ52125.1 - 0.001 18.1 0.0 0.0017 17.4 0.0 1.2 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_33 PF13671.1 CBZ52125.1 - 0.002 18.0 0.1 0.0049 16.7 0.0 1.7 2 0 0 2 2 1 1 AAA domain AAA_2 PF07724.9 CBZ52125.1 - 0.0036 17.2 0.0 0.0073 16.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 CBZ52125.1 - 0.0043 17.0 0.5 0.023 14.7 0.2 2.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.1 CBZ52125.1 - 0.012 15.4 0.0 0.048 13.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.1 CBZ52125.1 - 0.014 14.8 0.3 0.039 13.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.1 CBZ52125.1 - 0.015 15.2 0.1 0.079 12.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.16 CBZ52125.1 - 0.018 14.1 0.0 0.038 13.1 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI NACHT PF05729.7 CBZ52125.1 - 0.038 13.6 0.2 3.1 7.4 0.0 2.4 1 1 1 2 2 2 0 NACHT domain RNA_helicase PF00910.17 CBZ52125.1 - 0.064 13.4 0.0 0.49 10.6 0.0 2.5 2 0 0 2 2 2 0 RNA helicase AAA_18 PF13238.1 CBZ52125.1 - 0.069 13.4 0.3 0.21 11.9 0.0 2.0 2 0 0 2 2 1 0 AAA domain DUF927 PF06048.6 CBZ52125.1 - 0.12 11.6 0.0 0.19 10.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF927) AAA_11 PF13086.1 CBZ52125.1 - 0.13 11.8 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain PhoH PF02562.11 CBZ52125.1 - 0.17 11.0 0.1 0.32 10.1 0.1 1.3 1 0 0 1 1 1 0 PhoH-like protein AAA_24 PF13479.1 CBZ52125.1 - 0.18 11.3 0.0 0.29 10.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain PSK PF06404.7 CBZ52126.1 - 7.5 7.3 11.4 0.61 10.8 0.1 3.6 3 0 0 3 3 3 0 Phytosulfokine precursor protein (PSK) zf-RING_2 PF13639.1 CBZ52127.1 - 5.1e-12 45.4 8.4 8.2e-12 44.7 5.8 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 CBZ52127.1 - 5.4e-09 35.5 5.8 8.9e-09 34.8 4.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CBZ52127.1 - 1.5e-07 30.9 6.5 2.4e-07 30.2 4.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CBZ52127.1 - 3.2e-07 30.2 7.6 5.3e-07 29.5 5.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 CBZ52127.1 - 3.2e-07 30.3 5.7 5.8e-07 29.5 4.0 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 CBZ52127.1 - 1.4e-05 24.7 5.4 2.4e-05 23.9 3.7 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 CBZ52127.1 - 0.00052 19.8 6.4 0.001 18.8 4.4 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-Apc11 PF12861.2 CBZ52127.1 - 0.0068 16.2 4.3 0.012 15.4 3.0 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 CBZ52127.1 - 0.027 14.0 6.1 0.054 13.0 4.2 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.1 CBZ52127.1 - 0.09 12.5 3.0 0.33 10.7 2.1 2.0 1 1 0 1 1 1 0 RING-type zinc-finger zf-RING_6 PF14835.1 CBZ52127.1 - 0.3 10.8 5.2 2.2 8.1 3.3 2.1 1 1 1 2 2 2 0 zf-RING of BARD1-type protein zf-P11 PF03854.9 CBZ52127.1 - 1.1 8.7 6.3 2.9 7.4 4.4 1.6 1 1 0 1 1 1 0 P-11 zinc finger Pkinase PF00069.20 CBZ52128.1 - 5.7e-51 173.1 0.0 2.6e-28 98.9 0.1 2.0 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ52128.1 - 1.7e-29 102.7 0.0 2e-18 66.4 0.0 2.0 1 1 1 2 2 2 2 Protein tyrosine kinase TruD PF01142.13 CBZ52129.1 - 1.7e-46 158.6 0.0 3.5e-13 48.9 0.0 6.0 6 0 0 6 6 6 5 tRNA pseudouridine synthase D (TruD) DUF3883 PF13020.1 CBZ52130.1 - 5.2e-11 42.1 0.0 1e-10 41.1 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3883) eIF-5_eIF-2B PF01873.12 CBZ52131.1 - 2.9e-36 123.8 0.0 5.5e-36 122.9 0.0 1.5 1 0 0 1 1 1 1 Domain found in IF2B/IF5 W2 PF02020.13 CBZ52131.1 - 1.2e-13 50.7 0.7 1.2e-13 50.7 0.5 3.0 3 0 0 3 3 3 1 eIF4-gamma/eIF5/eIF2-epsilon CDC45 PF02724.9 CBZ52131.1 - 0.0028 15.7 10.7 0.0036 15.4 7.4 1.2 1 0 0 1 1 1 1 CDC45-like protein Nop14 PF04147.7 CBZ52131.1 - 0.15 9.9 23.0 0.21 9.4 16.0 1.1 1 0 0 1 1 1 0 Nop14-like family eIF-3c_N PF05470.7 CBZ52131.1 - 0.46 8.5 14.3 0.63 8.0 9.9 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus EIIBC-GUT_N PF03612.9 CBZ52131.1 - 1.2 8.7 4.3 9.2 5.8 0.0 2.2 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus SAPS PF04499.10 CBZ52131.1 - 1.4 7.4 9.8 1.8 7.1 6.8 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein TFIIF_alpha PF05793.7 CBZ52131.1 - 3.9 5.7 35.4 6.3 5.0 24.6 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) FAM60A PF15396.1 CBZ52131.1 - 7.4 6.2 16.0 12 5.5 11.1 1.3 1 0 0 1 1 1 0 Protein Family FAM60A DUF4407 PF14362.1 CBZ52131.1 - 9.1 5.1 6.2 13 4.5 4.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) WLM PF08325.5 CBZ52132.1 - 2.4e-08 34.0 0.1 2.4e-08 34.0 0.1 2.7 3 0 0 3 3 3 1 WLM domain DUF45 PF01863.12 CBZ52132.1 - 1.7e-05 24.6 0.4 3.8e-05 23.5 0.3 1.5 1 0 0 1 1 1 1 Protein of unknown function DUF45 A_deamin PF02137.13 CBZ52134.1 - 6e-32 111.3 0.0 8.2e-20 71.3 0.0 5.5 5 2 0 5 5 5 3 Adenosine-deaminase (editase) domain NAD_kinase PF01513.16 CBZ52136.1 - 2.5e-61 206.9 0.0 4.3e-61 206.1 0.0 1.3 1 0 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.19 CBZ52136.1 - 0.061 12.7 0.0 0.14 11.5 0.0 1.5 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain Flu_PB2 PF00604.12 CBZ52140.1 - 2.6 5.7 0.1 3.8 5.2 0.1 1.1 1 0 0 1 1 1 0 Influenza RNA-dependent RNA polymerase subunit PB2 zf-CCHC_3 PF13917.1 CBZ52141.1 - 2.5e-05 23.9 0.1 5.7e-05 22.7 0.1 1.6 1 0 0 1 1 1 1 Zinc knuckle SR-25 PF10500.4 CBZ52141.1 - 6.4e-05 22.5 40.5 8.6e-05 22.1 28.1 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein zf-CCHC PF00098.18 CBZ52141.1 - 0.00044 20.0 2.0 0.0007 19.3 1.4 1.3 1 0 0 1 1 1 1 Zinc knuckle RR_TM4-6 PF06459.7 CBZ52141.1 - 3.6 7.3 13.6 4.8 6.9 9.4 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF572 PF04502.8 CBZ52141.1 - 5.6 6.0 21.8 7.5 5.6 15.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) GMC_oxred_C PF05199.8 CBZ52142.1 - 3.4e-23 82.5 0.0 1.1e-17 64.6 0.0 2.5 2 0 0 2 2 2 2 GMC oxidoreductase GMC_oxred_N PF00732.14 CBZ52142.1 - 1.3e-19 70.5 0.1 1.6e-10 40.6 0.0 3.1 2 1 0 2 2 2 2 GMC oxidoreductase FAD_binding_2 PF00890.19 CBZ52142.1 - 8.6e-06 24.8 0.1 1.2e-05 24.3 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 CBZ52142.1 - 9.8e-05 22.3 0.1 0.00031 20.6 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 CBZ52142.1 - 0.00035 19.6 0.5 0.00071 18.5 0.2 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.9 CBZ52142.1 - 0.00086 17.8 0.1 0.0013 17.3 0.1 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_2 PF07992.9 CBZ52142.1 - 0.0012 18.8 0.4 0.0019 18.1 0.3 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 CBZ52142.1 - 0.0012 19.1 0.0 0.0036 17.6 0.0 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 CBZ52142.1 - 0.014 14.5 0.0 0.036 13.1 0.0 1.6 2 0 0 2 2 2 0 FAD binding domain GIDA PF01134.17 CBZ52142.1 - 0.018 13.9 0.4 0.028 13.2 0.3 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Thi4 PF01946.12 CBZ52142.1 - 0.027 13.5 0.0 0.049 12.7 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Pyr_redox_3 PF13738.1 CBZ52142.1 - 0.029 14.4 0.1 0.062 13.3 0.1 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.11 CBZ52142.1 - 0.039 13.4 0.1 0.07 12.5 0.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Lycopene_cycl PF05834.7 CBZ52142.1 - 0.12 11.3 0.0 0.17 10.7 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Sec3-PIP2_bind PF15277.1 CBZ52143.1 - 0.00051 19.8 0.0 0.00093 19.0 0.0 1.4 1 0 0 1 1 1 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH PH_6 PF15406.1 CBZ52143.1 - 0.0094 16.0 0.0 0.025 14.6 0.0 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 CBZ52143.1 - 0.011 15.9 0.0 0.023 14.8 0.0 1.6 1 0 0 1 1 1 0 PH domain DUF2379 PF09543.5 CBZ52143.1 - 0.014 15.3 2.0 0.023 14.6 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2379) PH_4 PF15404.1 CBZ52143.1 - 0.21 11.0 0.0 0.21 11.0 0.0 2.3 3 0 0 3 3 3 0 Pleckstrin homology domain RR_TM4-6 PF06459.7 CBZ52143.1 - 2.9 7.7 6.4 4.7 7.0 4.5 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 ADH_zinc_N PF00107.21 CBZ52144.1 - 9.6e-23 80.1 0.0 1.6e-22 79.4 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 CBZ52144.1 - 2.1e-14 54.4 0.0 1e-13 52.2 0.0 2.1 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 CBZ52144.1 - 1.9e-09 37.2 0.0 9.9e-08 31.7 0.0 2.4 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain RNA_pol_Rpb1_5 PF04998.12 CBZ52145.1 - 5.7e-79 265.2 0.0 3e-78 262.9 0.0 2.2 2 1 0 2 2 2 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.15 CBZ52145.1 - 1.4e-48 164.9 0.2 2.6e-30 105.5 0.0 2.4 2 0 0 2 2 2 2 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 CBZ52145.1 - 5.8e-25 87.8 0.0 1.3e-24 86.7 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.12 CBZ52145.1 - 2.3e-19 69.1 0.1 6.4e-19 67.6 0.1 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_1 PF04997.7 CBZ52145.1 - 7.9e-15 54.9 5.1 1.7e-13 50.5 0.0 3.3 2 1 0 2 2 2 1 RNA polymerase Rpb1, domain 1 Cyclin PF08613.6 CBZ52146.1 - 1.7e-13 51.1 0.1 4.3e-07 30.4 0.0 2.2 2 0 0 2 2 2 2 Cyclin Dynein_light PF01221.13 CBZ52147.1 - 8.4e-25 86.5 0.2 9.7e-25 86.3 0.2 1.1 1 0 0 1 1 1 1 Dynein light chain type 1 Daxx PF03344.10 CBZ52149.1 - 0.71 8.2 7.4 0.75 8.2 5.1 1.0 1 0 0 1 1 1 0 Daxx Family Nop14 PF04147.7 CBZ52149.1 - 3.2 5.5 8.2 3.5 5.4 5.7 1.0 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.5 CBZ52149.1 - 4.5 6.2 8.4 5.2 6.0 5.9 1.0 1 0 0 1 1 1 0 BUD22 CDC45 PF02724.9 CBZ52149.1 - 7.3 4.4 7.1 8.1 4.3 4.9 1.0 1 0 0 1 1 1 0 CDC45-like protein SNF2_N PF00176.18 CBZ52150.1 - 5.4e-72 242.1 1.7 5.4e-72 242.1 1.2 2.2 2 1 1 3 3 3 1 SNF2 family N-terminal domain Helicase_C PF00271.26 CBZ52150.1 - 4.7e-15 55.2 0.5 1.2e-14 53.9 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 CBZ52150.1 - 0.0053 16.6 2.3 0.017 14.9 0.0 2.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.3 CBZ52150.1 - 0.094 11.5 0.0 6.1 5.5 0.0 2.3 2 0 0 2 2 2 0 Class II histone deacetylase complex subunits 2 and 3 Gpi1 PF05024.10 CBZ52151.1 - 2.8e-30 105.3 3.9 4.8e-22 78.5 0.8 2.3 2 0 0 2 2 2 2 N-acetylglucosaminyl transferase component (Gpi1) Dus PF01207.12 CBZ52152.1 - 1.2e-51 175.4 0.0 3.5e-51 173.8 0.0 1.8 2 1 0 2 2 2 1 Dihydrouridine synthase (Dus) Oxidored_FMN PF00724.15 CBZ52152.1 - 0.22 10.4 0.0 0.72 8.7 0.0 1.7 1 1 0 1 1 1 0 NADH:flavin oxidoreductase / NADH oxidase family RCC1 PF00415.13 CBZ52153.1 - 2.2e-27 95.0 10.7 3.3e-09 36.7 0.0 6.7 6 1 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 CBZ52153.1 - 5.4e-22 76.8 18.9 5.5e-06 25.8 0.7 5.6 5 0 0 5 5 5 5 Regulator of chromosome condensation (RCC1) repeat UQ_con PF00179.21 CBZ52154.1 - 5.6e-36 123.0 0.0 6.6e-36 122.8 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme ER PF01133.12 CBZ52155.1 - 1.2e-36 124.4 0.5 1.4e-36 124.3 0.3 1.0 1 0 0 1 1 1 1 Enhancer of rudimentary Peptidase_S24 PF00717.18 CBZ52156.1 - 2.7e-12 46.1 0.1 6.6e-12 44.9 0.0 1.7 1 0 0 1 1 1 1 Peptidase S24-like ParA PF10609.4 CBZ52157.1 - 5.4e-30 103.1 0.1 1.9e-29 101.3 0.1 1.9 1 1 1 2 2 2 1 ParA/MinD ATPase like CbiA PF01656.18 CBZ52157.1 - 1.8e-17 63.3 0.0 2.7e-17 62.8 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ArsA_ATPase PF02374.10 CBZ52157.1 - 0.00019 20.5 1.0 0.00073 18.6 0.1 2.1 2 1 0 2 2 2 1 Anion-transporting ATPase AAA_26 PF13500.1 CBZ52157.1 - 0.002 17.7 0.5 0.031 13.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain MipZ PF09140.6 CBZ52157.1 - 0.0035 16.4 0.1 0.01 14.9 0.0 1.7 1 1 0 1 1 1 1 ATPase MipZ AAA_25 PF13481.1 CBZ52157.1 - 0.0036 16.7 0.1 0.0073 15.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.17 CBZ52157.1 - 0.0057 15.5 0.1 0.0082 15.0 0.1 1.2 1 0 0 1 1 1 1 NB-ARC domain DUF258 PF03193.11 CBZ52157.1 - 0.0071 15.5 0.1 0.013 14.6 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_31 PF13614.1 CBZ52157.1 - 0.0096 15.8 0.1 0.13 12.1 0.0 2.5 3 0 0 3 3 3 1 AAA domain ArgK PF03308.11 CBZ52157.1 - 0.017 13.8 0.5 0.027 13.2 0.3 1.3 1 0 0 1 1 1 0 ArgK protein IstB_IS21 PF01695.12 CBZ52157.1 - 0.049 13.0 0.1 0.08 12.3 0.1 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA PF00004.24 CBZ52157.1 - 0.17 12.0 0.0 0.35 11.0 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.8 CBZ52157.1 - 0.23 10.3 0.0 0.32 9.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Abi PF02517.11 CBZ52158.1 - 2e-20 72.7 0.0 1.2e-18 66.9 0.0 2.9 2 1 0 2 2 2 1 CAAX protease self-immunity Proteasome PF00227.21 CBZ52159.1 - 1.2e-27 96.4 0.0 2.6e-27 95.3 0.0 1.5 1 1 0 1 1 1 1 Proteasome subunit OKR_DC_1 PF01276.15 CBZ52160.1 - 8e-72 242.0 0.0 4.3e-51 173.7 0.0 2.2 2 0 0 2 2 2 2 Orn/Lys/Arg decarboxylase, major domain OKR_DC_1_C PF03711.10 CBZ52160.1 - 0.0022 18.0 0.0 0.0049 16.9 0.0 1.5 1 0 0 1 1 1 1 Orn/Lys/Arg decarboxylase, C-terminal domain Aminotran_1_2 PF00155.16 CBZ52160.1 - 0.0057 15.6 0.0 0.0097 14.8 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 CBZ52160.1 - 0.019 14.1 0.0 0.038 13.1 0.0 1.4 1 0 0 1 1 1 0 Beta-eliminating lyase GFO_IDH_MocA PF01408.17 CBZ52160.1 - 0.16 12.4 0.1 0.95 9.9 0.0 2.2 1 1 1 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold DNA_pol_E_B PF04042.11 CBZ52161.1 - 6.7e-15 54.9 0.0 2e-14 53.3 0.0 1.8 1 1 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Sugar_transport PF06800.7 CBZ52162.1 - 5.4e-10 38.8 15.0 1.3e-05 24.4 2.7 2.3 2 0 0 2 2 2 2 Sugar transport protein EamA PF00892.15 CBZ52162.1 - 1.8 8.5 30.7 0.29 11.1 8.4 3.3 3 2 1 4 4 4 0 EamA-like transporter family HECT PF00632.20 CBZ52163.1 - 4.7e-43 147.5 0.0 7.8e-43 146.8 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) CoA_binding_3 PF13727.1 CBZ52163.1 - 2.3 8.0 0.4 10 5.9 0.0 2.1 2 0 0 2 2 2 0 CoA-binding domain DUF1012 PF06241.7 CBZ52163.1 - 7 6.1 0.0 12 5.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1012) SRP54 PF00448.17 CBZ52165.1 - 3e-54 183.4 0.3 9.5e-54 181.8 0.2 1.8 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain SRP-alpha_N PF04086.8 CBZ52165.1 - 1.4e-11 44.2 12.7 1.9e-10 40.6 2.5 2.2 1 1 1 2 2 2 2 Signal recognition particle, alpha subunit, N-terminal CbiA PF01656.18 CBZ52165.1 - 0.0003 20.2 0.7 0.0021 17.4 0.5 2.1 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ArgK PF03308.11 CBZ52165.1 - 0.00038 19.3 0.0 0.00078 18.2 0.0 1.5 1 0 0 1 1 1 1 ArgK protein AAA_30 PF13604.1 CBZ52165.1 - 0.0006 19.4 0.2 0.001 18.6 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 CBZ52165.1 - 0.00069 19.6 0.2 0.0036 17.2 0.0 2.3 3 0 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.1 CBZ52165.1 - 0.0013 18.8 0.0 0.0045 17.1 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 CBZ52165.1 - 0.0046 16.8 0.1 0.043 13.6 0.0 2.4 3 0 0 3 3 3 1 AAA domain NTPase_1 PF03266.10 CBZ52165.1 - 0.0095 15.6 0.5 5.4 6.6 0.0 2.7 3 0 0 3 3 3 2 NTPase ETF PF01012.16 CBZ52165.1 - 0.052 13.2 0.4 0.69 9.6 0.1 2.4 2 0 0 2 2 2 0 Electron transfer flavoprotein domain DAP3 PF10236.4 CBZ52165.1 - 0.061 12.2 0.0 0.11 11.3 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 MobB PF03205.9 CBZ52165.1 - 0.072 12.7 0.5 0.55 9.9 0.0 2.6 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B DUF4175 PF13779.1 CBZ52165.1 - 0.59 7.7 7.6 0.86 7.2 5.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) tRNA-synt_His PF13393.1 CBZ52166.1 - 7.1e-46 156.6 0.0 1.7e-45 155.4 0.0 1.7 1 0 0 1 1 1 1 Histidyl-tRNA synthetase tRNA-synt_2b PF00587.20 CBZ52166.1 - 2.2e-15 56.6 0.0 3.8e-15 55.9 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 CBZ52166.1 - 1.7e-10 40.6 0.0 4.1e-10 39.4 0.0 1.7 1 0 0 1 1 1 1 Anticodon binding domain Lyase_aromatic PF00221.14 CBZ52166.1 - 2.4e-10 39.4 1.8 1.1e-09 37.3 1.3 1.8 1 1 0 1 1 1 1 Aromatic amino acid lyase tRNA-synt_2 PF00152.15 CBZ52166.1 - 0.00094 18.0 0.1 0.0049 15.6 0.0 2.0 2 1 0 2 2 2 1 tRNA synthetases class II (D, K and N) tRNA-synt_2d PF01409.15 CBZ52166.1 - 0.013 14.7 0.0 0.026 13.7 0.0 1.4 1 0 0 1 1 1 0 tRNA synthetases class II core domain (F) AIRS_C PF02769.17 CBZ52170.1 - 1.3e-19 70.6 0.1 7.2e-19 68.2 0.1 2.2 1 1 0 1 1 1 1 AIR synthase related protein, C-terminal domain Pyr_redox_2 PF07992.9 CBZ52170.1 - 1.1e-07 31.8 0.0 7.1e-07 29.3 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase AIRS PF00586.19 CBZ52170.1 - 5.8e-07 29.6 0.0 3.5e-06 27.1 0.0 2.4 2 0 0 2 2 2 1 AIR synthase related protein, N-terminal domain Clat_adaptor_s PF01217.15 CBZ52171.1 - 9.7e-09 35.0 0.1 1.4e-08 34.5 0.1 1.2 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Ecm29 PF13001.2 CBZ52172.1 - 7.5e-19 67.5 0.0 5.3e-18 64.7 0.0 2.2 1 1 0 1 1 1 1 Proteasome stabiliser HEAT PF02985.17 CBZ52172.1 - 0.1 12.7 8.1 0.34 11.0 0.1 5.6 5 0 0 5 5 5 0 HEAT repeat Ctr PF04145.10 CBZ52172.1 - 8 6.5 8.2 11 6.1 0.1 5.2 6 0 0 6 6 6 0 Ctr copper transporter family DTW PF03942.10 CBZ52173.1 - 4.7e-12 45.5 0.2 5.7e-05 22.4 0.0 3.3 3 0 0 3 3 3 3 DTW domain Dpy-30 PF05186.8 CBZ52175.1 - 3e-14 52.2 0.4 4.8e-14 51.5 0.3 1.3 1 0 0 1 1 1 1 Dpy-30 motif RIIa PF02197.12 CBZ52175.1 - 0.14 11.6 0.1 0.24 10.8 0.1 1.3 1 0 0 1 1 1 0 Regulatory subunit of type II PKA R-subunit Sulfate_transp PF00916.15 CBZ52176.1 - 7.8e-24 84.1 9.2 5.6e-23 81.3 6.4 2.2 1 1 0 1 1 1 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 CBZ52176.1 - 1.9e-08 33.8 4.8 1.9e-08 33.8 3.4 2.0 2 0 0 2 2 2 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 CBZ52176.1 - 0.034 13.5 0.0 0.068 12.5 0.0 1.5 1 0 0 1 1 1 0 STAS domain Ufd2P_core PF10408.4 CBZ52177.1 - 2.4e-122 409.2 0.0 3.3e-122 408.8 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.10 CBZ52177.1 - 1.2e-21 76.4 2.0 2.9e-21 75.2 1.4 1.7 1 0 0 1 1 1 1 U-box domain COPI_assoc PF08507.5 CBZ52178.1 - 3.3e-09 36.5 2.8 4.4e-09 36.1 1.9 1.1 1 0 0 1 1 1 1 COPI associated protein EF-hand_7 PF13499.1 CBZ52178.1 - 9.1e-09 35.3 3.9 2e-08 34.2 2.7 1.6 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.27 CBZ52178.1 - 4e-08 32.0 2.6 2.5e-05 23.2 0.1 2.9 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.1 CBZ52178.1 - 5.5e-08 32.0 3.3 0.0005 19.7 0.1 3.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.1 CBZ52178.1 - 7.3e-07 28.7 1.0 1.6e-06 27.6 0.7 1.5 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.1 CBZ52178.1 - 6.5e-05 22.0 2.8 0.00021 20.4 0.1 2.5 2 0 0 2 2 2 1 EF hand ACDC PF14733.1 CBZ52179.1 - 1.3e-18 66.8 0.0 2.6e-18 65.9 0.0 1.5 1 0 0 1 1 1 1 AP2-coincident C-terminal AP2 PF00847.15 CBZ52179.1 - 1.6e-11 44.1 0.2 3.3e-11 43.1 0.1 1.5 1 0 0 1 1 1 1 AP2 domain AP2 PF00847.15 CBZ52180.1 - 2.1e-11 43.7 0.2 3.8e-11 42.9 0.1 1.4 1 0 0 1 1 1 1 AP2 domain DUF3243 PF11588.3 CBZ52181.1 - 0.16 11.9 0.1 0.32 11.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3243) UQ_con PF00179.21 CBZ52182.1 - 3.4e-39 133.4 0.0 3.7e-39 133.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 CBZ52182.1 - 0.014 15.1 0.1 0.024 14.3 0.1 1.5 1 1 0 1 1 1 0 Prokaryotic E2 family B RWD PF05773.17 CBZ52182.1 - 0.019 14.8 0.0 0.019 14.8 0.0 1.2 1 0 0 1 1 1 0 RWD domain DUF2353 PF09789.4 CBZ52183.1 - 9.8e-07 28.3 35.1 9.7e-06 25.0 13.3 2.4 1 1 1 2 2 2 2 Uncharacterized coiled-coil protein (DUF2353) BTK PF00779.14 CBZ52183.1 - 0.00053 19.5 4.1 0.0012 18.4 2.8 1.6 1 0 0 1 1 1 1 BTK motif GAS PF13851.1 CBZ52183.1 - 0.00088 18.5 42.7 0.0058 15.8 5.7 3.2 1 1 2 3 3 3 3 Growth-arrest specific micro-tubule binding APG6 PF04111.7 CBZ52183.1 - 0.002 17.2 46.7 0.0025 16.9 14.6 3.1 1 1 2 3 3 3 2 Autophagy protein Apg6 Tropomyosin_1 PF12718.2 CBZ52183.1 - 0.008 16.0 15.8 0.008 16.0 10.9 2.7 1 1 1 2 2 1 1 Tropomyosin like AAA_27 PF13514.1 CBZ52183.1 - 0.0086 13.8 33.9 0.013 13.2 23.5 1.2 1 0 0 1 1 1 1 AAA domain Leu_zip PF15294.1 CBZ52183.1 - 0.016 14.3 41.3 0.05 12.7 3.7 3.2 1 1 2 3 3 3 0 Leucine zipper Reo_sigmaC PF04582.7 CBZ52183.1 - 0.039 13.1 12.7 0.49 9.5 4.0 2.4 1 1 1 2 2 2 0 Reovirus sigma C capsid protein EAP30 PF04157.11 CBZ52183.1 - 0.057 12.5 18.1 0.015 14.4 2.8 2.6 2 0 0 2 2 2 0 EAP30/Vps36 family DUF3584 PF12128.3 CBZ52183.1 - 0.13 9.6 44.4 0.024 12.0 10.9 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) ATG16 PF08614.6 CBZ52183.1 - 0.15 11.8 41.7 0.064 13.0 3.4 3.6 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) zinc_ribbon_2 PF13240.1 CBZ52183.1 - 0.23 11.0 3.5 0.2 11.1 0.9 2.1 2 0 0 2 2 2 0 zinc-ribbon domain IncA PF04156.9 CBZ52183.1 - 0.38 10.3 51.7 1.6 8.2 10.4 3.3 1 1 2 3 3 3 0 IncA protein DivIC PF04977.10 CBZ52183.1 - 0.9 9.0 33.4 0.22 11.0 0.7 4.9 2 2 2 4 4 4 0 Septum formation initiator TPR_MLP1_2 PF07926.7 CBZ52183.1 - 1 9.0 45.7 83 2.9 12.8 3.7 1 1 1 2 2 1 0 TPR/MLP1/MLP2-like protein Cytochrom_C_2 PF01322.15 CBZ52183.1 - 3.9 8.0 12.0 0.87 10.1 1.8 3.3 1 1 1 2 2 2 0 Cytochrome C' DUF3450 PF11932.3 CBZ52183.1 - 4.1 6.5 36.5 2.7 7.1 7.1 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF3450) DUF4201 PF13870.1 CBZ52183.1 - 4.8 6.5 40.8 4.2 6.7 9.3 3.9 1 1 3 4 4 4 0 Domain of unknown function (DUF4201) V_ATPase_I PF01496.14 CBZ52183.1 - 7.9 4.2 30.4 2.7 5.7 5.2 2.1 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family DUF342 PF03961.8 CBZ52183.1 - 8.7 4.6 27.8 2.8 6.2 9.7 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF342) DUF2730 PF10805.3 CBZ52183.1 - 9.9 5.9 19.6 6.3 6.5 0.8 4.2 3 1 1 4 4 4 0 Protein of unknown function (DUF2730) DUF1987 PF09345.5 CBZ52184.1 - 0.14 11.9 0.1 0.92 9.3 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1987) PDEase_I PF00233.14 CBZ52185.1 - 3.3e-61 207.0 0.1 6.1e-61 206.1 0.1 1.3 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase HD PF01966.17 CBZ52185.1 - 0.1 12.5 0.0 0.29 11.1 0.0 1.9 1 0 0 1 1 1 0 HD domain NusA_N PF08529.6 CBZ52185.1 - 0.12 12.3 0.4 0.28 11.1 0.1 1.7 2 0 0 2 2 2 0 NusA N-terminal domain Dpy19 PF10034.4 CBZ52186.1 - 1.3e-118 396.9 0.0 3.9e-70 236.8 0.0 2.5 2 1 0 2 2 2 2 Q-cell neuroblast polarisation DUF3130 PF11328.3 CBZ52187.1 - 0.13 12.3 0.1 0.36 10.9 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3130 PARG_cat PF05028.9 CBZ52188.1 - 3.5e-61 207.3 0.2 3.9e-60 203.8 0.1 1.9 1 1 0 1 1 1 1 Poly (ADP-ribose) glycohydrolase (PARG) zf-4CXXC_R1 PF10497.4 CBZ52188.1 - 0.0075 16.3 0.1 0.014 15.5 0.0 1.3 1 0 0 1 1 1 1 Zinc-finger domain of monoamine-oxidase A repressor R1 NYD-SP28_assoc PF14775.1 CBZ52189.1 - 0.063 12.9 2.7 0.14 11.8 1.9 1.5 1 0 0 1 1 1 0 Sperm tail C-terminal domain Rapamycin_bind PF08771.6 CBZ52189.1 - 0.16 12.0 0.6 0.47 10.5 0.4 1.7 2 0 0 2 2 2 0 Rapamycin binding domain zf-RING_2 PF13639.1 CBZ52191.1 - 9.3e-12 44.5 6.8 9.3e-12 44.5 4.7 2.2 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.2 CBZ52191.1 - 3.6e-07 30.2 7.6 2.1e-06 27.7 5.3 2.3 1 1 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 CBZ52191.1 - 2.3e-06 27.1 5.8 4.5e-06 26.2 4.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBZ52191.1 - 1.3e-05 24.8 3.9 3.5e-05 23.4 2.7 1.8 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 CBZ52191.1 - 1.4e-05 24.6 2.8 3.7e-05 23.2 1.9 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CBZ52191.1 - 0.00017 21.5 7.1 0.00017 21.5 4.9 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 CBZ52191.1 - 0.0038 17.0 4.1 0.016 15.0 2.8 2.0 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.3 CBZ52191.1 - 0.25 11.3 2.9 0.93 9.5 2.0 2.0 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_UBOX PF13445.1 CBZ52191.1 - 0.67 9.7 6.0 1.4 8.6 4.1 1.6 1 0 0 1 1 1 0 RING-type zinc-finger adh_short PF00106.20 CBZ52192.1 - 2.1e-23 83.0 4.9 1.1e-10 41.6 0.0 2.4 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.5 CBZ52192.1 - 5.9e-09 35.8 3.1 3.1e-07 30.2 0.8 2.4 2 0 0 2 2 2 2 KR domain Polysacc_synt_2 PF02719.10 CBZ52192.1 - 0.03 13.2 0.1 0.051 12.4 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Eno-Rase_NADH_b PF12242.3 CBZ52192.1 - 0.037 13.8 0.1 0.096 12.4 0.1 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase ExoD PF06055.7 CBZ52192.1 - 0.58 9.2 8.7 0.25 10.4 0.1 2.4 2 0 0 2 2 2 0 Exopolysaccharide synthesis, ExoD Abhydrolase_5 PF12695.2 CBZ52193.1 - 0.023 14.4 0.0 0.041 13.6 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 CBZ52193.1 - 0.034 13.3 0.0 0.055 12.6 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family DUF443 PF04276.7 CBZ52193.1 - 0.055 12.8 0.6 0.077 12.4 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF443) Spore_YtrH PF14034.1 CBZ52193.1 - 0.2 11.6 5.9 0.31 10.9 4.1 1.3 1 0 0 1 1 1 0 Sporulation protein YtrH DUF485 PF04341.7 CBZ52193.1 - 0.21 11.3 3.3 0.35 10.6 2.3 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF485 IncA PF04156.9 CBZ52193.1 - 3.6 7.1 6.9 6.7 6.2 4.8 1.4 1 0 0 1 1 1 0 IncA protein Abhydrolase_5 PF12695.2 CBZ52194.1 - 0.0029 17.3 0.0 0.006 16.3 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF1700 PF08006.6 CBZ52194.1 - 0.012 14.9 1.2 0.023 13.9 0.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) Peptidase_S9 PF00326.16 CBZ52194.1 - 0.013 14.7 0.1 0.049 12.8 0.0 1.8 1 1 0 2 2 2 0 Prolyl oligopeptidase family UPF0227 PF05728.7 CBZ52194.1 - 0.017 14.8 0.0 0.12 12.0 0.0 2.1 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0227) Cad PF03596.8 CBZ52194.1 - 0.054 13.1 3.2 0.089 12.4 2.0 1.6 1 1 0 1 1 1 0 Cadmium resistance transporter TMEM192 PF14802.1 CBZ52194.1 - 0.079 11.8 1.5 0.11 11.3 1.0 1.2 1 0 0 1 1 1 0 TMEM192 family DUF4131 PF13567.1 CBZ52194.1 - 0.16 11.3 4.2 0.24 10.7 2.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) DUF2207 PF09972.4 CBZ52194.1 - 0.19 10.2 1.5 0.27 9.7 1.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF2371 PF10177.4 CBZ52194.1 - 0.55 10.1 3.3 1.8 8.4 2.2 1.9 1 1 0 1 1 1 0 Uncharacterised conserved protein (DUF2371) LXG PF04740.7 CBZ52196.1 - 0.011 15.5 0.7 0.45 10.2 0.0 2.6 1 1 1 2 2 2 0 LXG domain of WXG superfamily V_ATPase_I PF01496.14 CBZ52196.1 - 5.6 4.6 6.1 9.2 3.9 2.9 1.9 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family ATG_C PF09333.6 CBZ52197.1 - 1.3e-06 28.4 0.0 4.2e-06 26.8 0.0 2.0 1 0 0 1 1 1 1 ATG C terminal domain Chorein_N PF12624.2 CBZ52197.1 - 5.5e-05 22.6 0.1 0.00011 21.6 0.1 1.4 1 0 0 1 1 1 1 N-terminal region of Chorein, a TM vesicle-mediated sorter Herpes_LMP2 PF07415.6 CBZ52197.1 - 7 5.1 0.3 24 3.3 0.2 1.9 1 0 0 1 1 1 0 Gammaherpesvirus latent membrane protein (LMP2) protein Peptidase_M3 PF01432.15 CBZ52198.1 - 0.27 10.2 0.0 0.7 8.8 0.0 1.6 2 0 0 2 2 2 0 Peptidase family M3 His_Phos_2 PF00328.17 CBZ52199.1 - 2.9e-42 145.2 0.0 1.1e-39 136.8 0.0 2.9 2 1 0 2 2 2 2 Histidine phosphatase superfamily (branch 2) RimK PF08443.6 CBZ52199.1 - 0.00014 21.4 0.0 0.00032 20.2 0.0 1.5 1 0 0 1 1 1 1 RimK-like ATP-grasp domain GST_C_3 PF14497.1 CBZ52200.1 - 3e-14 53.3 0.1 6.9e-14 52.1 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 CBZ52200.1 - 1e-08 35.2 0.0 9.3e-08 32.1 0.1 2.3 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.19 CBZ52200.1 - 1.7e-07 31.1 0.3 4.1e-07 29.8 0.2 1.7 1 0 0 1 1 1 1 Glutaredoxin GST_N_2 PF13409.1 CBZ52200.1 - 7.9e-05 22.5 0.0 0.0002 21.3 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 CBZ52200.1 - 0.019 14.8 0.0 0.094 12.6 0.0 2.2 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain KAAG1 PF15354.1 CBZ52200.1 - 0.063 13.6 2.8 0.18 12.1 0.0 2.9 2 0 0 2 2 2 0 Kidney-associated antigen 1 Laminin_G_3 PF13385.1 CBZ52202.1 - 5.3e-14 52.7 0.0 9.6e-14 51.9 0.0 1.4 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Laminin_G_2 PF02210.19 CBZ52202.1 - 1.7e-05 24.8 0.0 6.2e-05 23.0 0.0 1.8 2 0 0 2 2 2 1 Laminin G domain Laminin_G_1 PF00054.18 CBZ52202.1 - 0.00049 20.1 0.0 0.0023 17.9 0.0 1.9 2 0 0 2 2 2 1 Laminin G domain Sin3_corepress PF08295.7 CBZ52203.1 - 4.1e-22 77.8 0.0 8.5e-22 76.8 0.0 1.5 1 0 0 1 1 1 1 Sin3 family co-repressor DUF1620 PF07774.8 CBZ52204.1 - 1.2e-42 145.6 0.0 1.7e-42 145.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1620) PQQ_2 PF13360.1 CBZ52204.1 - 1.5e-07 31.0 8.1 0.00055 19.4 0.6 3.9 3 2 0 3 3 3 2 PQQ-like domain PQQ PF01011.16 CBZ52204.1 - 0.0027 17.1 0.7 3.8 7.2 0.0 4.6 4 0 0 4 4 4 1 PQQ enzyme repeat Misat_Tub_SegII PF10644.4 CBZ52204.1 - 0.2 11.6 0.0 0.44 10.6 0.0 1.5 1 0 0 1 1 1 0 Misato Segment II tubulin-like domain A_deaminase PF00962.17 CBZ52206.1 - 4e-41 141.0 0.0 5.2e-41 140.6 0.0 1.2 1 0 0 1 1 1 1 Adenosine/AMP deaminase tRNA-synt_2 PF00152.15 CBZ52207.1 - 3.1e-88 295.7 0.0 4e-88 295.4 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 CBZ52207.1 - 1.1e-11 44.3 0.1 2.2e-11 43.4 0.1 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 CBZ52207.1 - 5.5e-08 32.3 0.0 0.00014 21.1 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) tRNA-synt_2b PF00587.20 CBZ52207.1 - 0.028 14.0 0.0 1.9 8.0 0.0 2.3 2 0 0 2 2 2 0 tRNA synthetase class II core domain (G, H, P, S and T) Pro_isomerase PF00160.16 CBZ52208.1 - 1.7e-47 161.5 0.0 1.9e-47 161.3 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Thioredoxin_3 PF13192.1 CBZ52208.1 - 0.042 13.6 0.0 0.068 12.9 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin domain SF-assemblin PF06705.6 CBZ52211.1 - 7.4e-43 146.4 22.9 9e-43 146.1 15.9 1.0 1 0 0 1 1 1 1 SF-assemblin/beta giardin Baculo_PEP_C PF04513.7 CBZ52211.1 - 0.49 10.2 13.0 3.9 7.2 1.1 3.3 1 1 2 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Bcr-Abl_Oligo PF09036.5 CBZ52211.1 - 0.64 10.0 4.4 0.24 11.3 0.3 2.4 2 2 0 2 2 2 0 Bcr-Abl oncoprotein oligomerisation domain DUF1409 PF07197.7 CBZ52211.1 - 2.7 8.1 7.8 8.2 6.5 0.1 3.6 3 2 0 3 3 3 0 Protein of unknown function (DUF1409) Occludin_ELL PF07303.8 CBZ52211.1 - 3.3 8.5 11.9 3.6 8.3 0.7 3.0 1 1 2 3 3 3 0 Occludin homology domain F5_F8_type_C PF00754.20 CBZ52212.1 - 7.7e-18 64.5 1.0 4.8e-13 49.0 0.0 2.3 2 0 0 2 2 2 2 F5/8 type C domain DUF1080 PF06439.6 CBZ52212.1 - 0.035 13.9 0.0 8.4 6.2 0.0 2.4 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1080) BRE1 PF08647.6 CBZ52212.1 - 0.12 12.3 0.7 0.23 11.4 0.5 1.4 1 0 0 1 1 1 0 BRE1 E3 ubiquitin ligase TPR_MLP1_2 PF07926.7 CBZ52212.1 - 0.17 11.6 0.6 0.31 10.8 0.4 1.3 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein PA26 PF04636.8 CBZ52212.1 - 0.37 9.4 0.1 0.57 8.8 0.1 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) ACDC PF14733.1 CBZ52213.1 - 3.7e-17 62.2 0.3 6.7e-17 61.3 0.2 1.4 1 0 0 1 1 1 1 AP2-coincident C-terminal AP2 PF00847.15 CBZ52213.1 - 0.00039 20.5 0.1 0.00039 20.5 0.1 1.9 2 0 0 2 2 2 1 AP2 domain OATP PF03137.15 CBZ52215.1 - 1.3e-05 23.4 0.0 0.0091 14.0 0.0 3.1 3 0 0 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family MFS_2 PF13347.1 CBZ52215.1 - 0.49 8.7 0.5 1.7 6.9 0.2 1.9 2 0 0 2 2 2 0 MFS/sugar transport protein Sugar_tr PF00083.19 CBZ52215.1 - 1.1 7.7 8.5 0.018 13.6 0.4 1.9 2 0 0 2 2 2 0 Sugar (and other) transporter zf-RING_2 PF13639.1 CBZ52216.1 - 0.0022 17.7 2.5 0.0022 17.7 1.7 1.8 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 CBZ52216.1 - 0.016 15.2 2.3 0.016 15.2 1.6 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CBZ52216.1 - 0.016 14.8 1.5 0.033 13.8 1.0 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CBZ52216.1 - 1.9 8.2 4.4 0.48 10.1 0.6 1.8 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 CBZ52216.1 - 3.5 7.2 8.1 0.38 10.3 1.7 2.1 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Daxx PF03344.10 CBZ52216.1 - 9.3 4.6 20.4 14 4.0 14.2 1.2 1 0 0 1 1 1 0 Daxx Family SAG PF04092.8 CBZ52219.1 - 1.9e-41 141.3 25.6 7.2e-29 100.6 6.8 2.2 2 0 0 2 2 2 2 SRS domain SAG PF04092.8 CBZ52220.1 - 1.5e-43 148.0 32.4 5.6e-28 97.8 7.0 2.3 2 0 0 2 2 2 2 SRS domain SAG PF04092.8 CBZ52221.1 - 1.7e-44 151.1 29.8 6.4e-28 97.6 7.1 2.3 2 0 0 2 2 2 2 SRS domain SAG PF04092.8 CBZ52222.1 - 3.8e-43 146.8 30.8 2.3e-28 99.0 7.7 2.2 2 0 0 2 2 2 2 SRS domain SAG PF04092.8 CBZ52223.1 - 1.2e-45 154.9 30.1 3.3e-28 98.5 7.0 2.3 2 0 0 2 2 2 2 SRS domain SAG PF04092.8 CBZ52224.1 - 3.5e-43 146.9 29.3 7.9e-28 97.3 6.7 2.3 2 0 0 2 2 2 2 SRS domain SAG PF04092.8 CBZ52225.1 - 8.5e-42 142.4 26.9 2e-27 96.0 4.4 2.2 2 0 0 2 2 2 2 SRS domain Bac_surface_Ag PF01103.18 CBZ52226.1 - 3.5e-10 39.8 0.1 4.2e-08 33.0 0.1 3.0 1 1 0 1 1 1 1 Surface antigen NAC PF01849.13 CBZ52228.1 - 2.1e-18 65.5 0.1 4e-18 64.6 0.1 1.5 1 0 0 1 1 1 1 NAC domain UBA PF00627.26 CBZ52228.1 - 0.00069 19.3 0.2 0.0014 18.3 0.2 1.6 1 0 0 1 1 1 1 UBA/TS-N domain Peptidase_S64 PF08192.6 CBZ52228.1 - 0.046 12.0 1.9 0.056 11.7 1.3 1.0 1 0 0 1 1 1 0 Peptidase family S64 DUF1215 PF06744.7 CBZ52228.1 - 0.057 13.0 0.2 0.095 12.3 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1215) Pkinase PF00069.20 CBZ52229.1 - 2.8e-37 128.2 0.0 4.7e-21 75.1 0.0 3.1 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ52229.1 - 8.7e-16 57.7 0.0 2.8e-10 39.7 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 CBZ52229.1 - 1.6e-08 33.8 0.0 2e-05 23.7 0.0 2.2 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 CBZ52229.1 - 0.0084 15.8 0.4 0.018 14.7 0.1 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family DEAD PF00270.24 CBZ52230.1 - 2.6e-27 95.3 0.0 2.1e-13 50.1 0.0 2.4 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.26 CBZ52230.1 - 3.4e-19 68.4 0.0 1.7e-18 66.2 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 CBZ52230.1 - 1.2e-17 63.1 0.2 2.6e-17 62.1 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.10 CBZ52230.1 - 0.0079 16.0 0.0 6.7 6.4 0.0 2.7 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit AAA_22 PF13401.1 CBZ52230.1 - 0.034 14.2 0.0 0.81 9.8 0.0 2.6 2 0 0 2 2 2 0 AAA domain MFS_1 PF07690.11 CBZ52231.1 - 7e-12 44.7 16.5 3.8e-08 32.4 3.4 2.5 2 0 0 2 2 2 2 Major Facilitator Superfamily Nop PF01798.13 CBZ52232.1 - 1.1e-52 177.3 1.7 2.4e-52 176.2 1.2 1.6 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 CBZ52232.1 - 6.9e-28 96.2 0.6 1.2e-27 95.4 0.1 1.7 2 0 0 2 2 2 1 NOSIC (NUC001) domain NOP5NT PF08156.8 CBZ52232.1 - 3.9e-19 68.5 0.8 1.1e-18 67.1 0.5 1.8 1 0 0 1 1 1 1 NOP5NT (NUC127) domain Utp14 PF04615.8 CBZ52233.1 - 2.4e-73 247.5 73.8 2.4e-73 247.5 51.1 2.8 1 1 1 2 2 2 1 Utp14 protein BT1 PF03092.11 CBZ52234.1 - 9.2e-76 255.2 21.0 1.4e-75 254.7 14.5 1.2 1 0 0 1 1 1 1 BT1 family MFS_1 PF07690.11 CBZ52234.1 - 9.7e-14 50.8 38.2 4.6e-07 28.8 11.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 CBZ52234.1 - 4.2e-07 28.7 34.9 0.00017 20.1 7.0 2.5 1 1 1 2 2 2 2 MFS/sugar transport protein GTP_EFTU PF00009.22 CBZ52236.1 - 6.9e-62 208.2 0.1 1.1e-61 207.5 0.1 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 CBZ52236.1 - 3.2e-35 120.2 0.0 9.2e-35 118.8 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.19 CBZ52236.1 - 5.6e-22 77.4 0.0 1.2e-21 76.3 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.1 CBZ52236.1 - 1.8e-14 53.2 0.0 3.5e-14 52.4 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.20 CBZ52236.1 - 6.9e-12 45.3 0.3 5.3e-11 42.4 0.0 2.6 3 0 0 3 3 3 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 CBZ52236.1 - 0.00027 20.8 0.0 0.00061 19.7 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase zf-AN1 PF01428.11 CBZ52237.1 - 3.8e-22 77.8 25.2 2.1e-11 43.5 5.1 2.7 3 0 0 3 3 3 2 AN1-like Zinc finger Transp_Tc5_C PF04236.10 CBZ52237.1 - 4.7e-05 23.5 14.8 0.0043 17.2 1.7 2.4 2 0 0 2 2 2 2 Tc5 transposase C-terminal domain FYVE PF01363.16 CBZ52237.1 - 0.013 15.3 18.7 0.023 14.5 4.2 2.5 2 0 0 2 2 2 0 FYVE zinc finger Tnp_zf-ribbon_2 PF13842.1 CBZ52237.1 - 0.19 12.1 25.2 1.2 9.5 7.0 3.8 1 1 2 3 3 3 0 DDE_Tnp_1-like zinc-ribbon C1_3 PF07649.7 CBZ52237.1 - 0.36 10.8 14.5 2.3 8.3 0.2 3.4 3 0 0 3 3 3 0 C1-like domain C1_4 PF07975.7 CBZ52237.1 - 0.62 10.1 22.2 1.5 8.8 4.3 3.8 1 1 2 3 3 3 0 TFIIH C1-like domain Zn_Tnp_IS1595 PF12760.2 CBZ52237.1 - 1.6 8.5 19.5 9.6 6.1 2.4 3.4 2 1 1 3 3 3 0 Transposase zinc-ribbon domain DUF2180 PF09947.4 CBZ52237.1 - 2.2 8.1 9.3 7.5 6.3 0.2 3.0 2 1 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2180) zf-UBP PF02148.14 CBZ52237.1 - 3.1 7.9 13.0 20 5.3 2.1 3.3 2 1 1 3 3 3 0 Zn-finger in ubiquitin-hydrolases and other protein zf-B_box PF00643.19 CBZ52237.1 - 4.3 7.3 19.3 4 7.4 1.8 3.6 3 0 0 3 3 3 0 B-box zinc finger zf-H2C2_2 PF13465.1 CBZ52237.1 - 5.1 7.5 13.8 4.5 7.7 1.2 4.0 3 1 0 3 3 3 0 Zinc-finger double domain Cpn60_TCP1 PF00118.19 CBZ52239.1 - 4.8e-159 530.0 7.2 5.5e-159 529.8 5.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Acyl-CoA_dh_1 PF00441.19 CBZ52240.1 - 1.6e-24 86.6 0.2 2.4e-24 86.1 0.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_2 PF08028.6 CBZ52240.1 - 7.2e-06 26.2 0.0 1.2e-05 25.5 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Semialdhyde_dh PF01118.19 CBZ52241.1 - 1.9e-25 89.5 0.0 3.3e-25 88.7 0.0 1.3 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Semialdhyde_dhC PF02774.13 CBZ52241.1 - 3.9e-21 75.7 0.0 4e-19 69.2 0.0 2.2 1 1 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain DapB_N PF01113.15 CBZ52241.1 - 0.0043 16.9 0.1 0.013 15.3 0.0 1.9 2 0 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus NAD_binding_10 PF13460.1 CBZ52241.1 - 0.091 12.7 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 NADH(P)-binding DXP_reductoisom PF02670.11 CBZ52241.1 - 0.13 12.8 0.0 0.34 11.4 0.0 1.8 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase PseudoU_synth_2 PF00849.17 CBZ52242.1 - 3.8e-19 69.1 0.0 3.8e-18 65.8 0.0 2.3 1 1 0 1 1 1 1 RNA pseudouridylate synthase SNF2_N PF00176.18 CBZ52243.1 - 9.7e-58 195.3 0.0 1.3e-57 194.8 0.0 1.1 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 CBZ52243.1 - 3.2e-13 49.3 0.0 2.9e-12 46.2 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 CBZ52243.1 - 7.6e-08 32.0 0.0 1.2e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase HDA2-3 PF11496.3 CBZ52243.1 - 5.4e-05 22.1 0.0 0.00017 20.4 0.0 1.7 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.10 CBZ52243.1 - 0.0019 18.0 0.0 0.0037 17.1 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF2439 PF10382.4 CBZ52243.1 - 0.028 14.6 0.0 0.066 13.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2439) DUF2075 PF09848.4 CBZ52243.1 - 0.085 11.8 0.0 0.12 11.2 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) FBPase PF00316.15 CBZ52245.1 - 5.2e-86 288.4 0.0 6.5e-86 288.1 0.0 1.0 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase ELO PF01151.13 CBZ52248.1 - 2.7e-65 220.1 26.7 3.2e-65 219.9 18.5 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family Ribosomal_L7Ae PF01248.21 CBZ52249.1 - 1.5e-27 94.9 1.4 1.8e-27 94.6 0.7 1.3 1 1 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family SpoU_sub_bind PF08032.7 CBZ52249.1 - 0.025 14.7 0.0 0.046 13.8 0.0 1.4 1 0 0 1 1 1 0 RNA 2'-O ribose methyltransferase substrate binding Glyco_transf_4 PF13439.1 CBZ52249.1 - 0.15 11.8 0.0 0.22 11.2 0.0 1.3 1 1 0 1 1 1 0 Glycosyltransferase Family 4 Antimicrobial19 PF08225.6 CBZ52249.1 - 0.18 11.2 0.7 9.2 5.7 0.0 2.8 3 0 0 3 3 3 0 Pseudin antimicrobial peptide DUF4191 PF13829.1 CBZ52250.1 - 2.7 7.0 8.7 1.2 8.1 2.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) DUF3249 PF11615.3 CBZ52251.1 - 0.0066 16.1 0.1 60 3.4 0.0 4.6 5 0 0 5 5 5 1 Protein of unknown function (DUF3249) Xin PF08043.7 CBZ52251.1 - 0.067 12.8 3.3 6.9 6.6 0.0 4.9 5 0 0 5 5 5 0 Xin repeat TauE PF01925.14 CBZ52252.1 - 1.3e-19 70.6 32.4 3.1e-11 43.1 4.0 2.8 3 0 0 3 3 3 2 Sulfite exporter TauE/SafE DUF4381 PF14316.1 CBZ52252.1 - 0.076 13.1 1.8 14 5.7 0.1 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) SMP_2 PF10144.4 CBZ52252.1 - 0.12 11.5 0.1 0.39 9.7 0.0 1.8 2 0 0 2 2 2 0 Bacterial virulence factor haemolysin SieB PF14163.1 CBZ52252.1 - 0.43 10.1 4.9 5 6.6 0.0 2.7 3 0 0 3 3 3 0 Superinfection exclusion protein B WBP-1 PF11669.3 CBZ52252.1 - 1.6 8.8 5.9 17 5.5 0.0 3.0 3 0 0 3 3 3 0 WW domain-binding protein 1 Neur_chan_memb PF02932.11 CBZ52252.1 - 2.4 7.9 5.6 2 8.2 0.1 2.5 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region DSPc PF00782.15 CBZ52253.1 - 2.8e-09 36.6 0.0 4.6e-09 35.9 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain CBM_20 PF00686.14 CBZ52253.1 - 0.00023 20.6 0.0 0.00087 18.8 0.0 2.0 2 0 0 2 2 2 1 Starch binding domain Y_phosphatase PF00102.22 CBZ52253.1 - 0.17 11.2 0.1 0.32 10.3 0.0 1.4 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Ion_trans PF00520.26 CBZ52255.1 - 3.8e-74 248.2 99.5 4.8e-21 74.9 15.6 4.4 4 0 0 4 4 4 4 Ion transport protein CLPTM1 PF05602.7 CBZ52256.1 - 9.3e-84 281.6 0.0 6.5e-83 278.8 0.2 1.9 2 0 0 2 2 2 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) PQ-loop PF04193.9 CBZ52256.1 - 4e-06 26.2 3.1 0.049 13.1 0.1 2.8 2 0 0 2 2 2 2 PQ loop repeat DUF1240 PF06836.7 CBZ52256.1 - 0.36 11.0 8.8 0.079 13.1 1.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1240) PRP1_N PF06424.7 CBZ52257.1 - 2.5e-44 150.8 4.5 2.1e-42 144.6 0.8 3.7 3 0 0 3 3 2 2 PRP1 splicing factor, N-terminal TPR_14 PF13428.1 CBZ52257.1 - 4.3e-33 110.7 26.3 0.0007 20.0 0.0 13.5 7 3 7 14 14 13 10 Tetratricopeptide repeat TPR_19 PF14559.1 CBZ52257.1 - 2.5e-24 85.3 8.7 0.0067 16.7 0.0 9.7 6 1 3 9 9 9 5 Tetratricopeptide repeat TPR_16 PF13432.1 CBZ52257.1 - 1e-14 54.7 20.1 0.0047 17.5 0.0 8.7 7 1 0 8 8 8 4 Tetratricopeptide repeat TPR_11 PF13414.1 CBZ52257.1 - 2.8e-14 52.5 10.9 0.0061 16.1 0.0 9.8 6 2 4 10 10 10 2 TPR repeat TPR_2 PF07719.12 CBZ52257.1 - 5.2e-10 38.4 13.3 0.18 11.7 0.1 8.9 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_8 PF13181.1 CBZ52257.1 - 2.5e-07 29.9 0.1 0.99 9.3 0.0 6.3 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_17 PF13431.1 CBZ52257.1 - 1.8e-06 27.6 2.6 2.1 8.7 0.0 6.9 6 1 1 7 7 7 1 Tetratricopeptide repeat TPR_12 PF13424.1 CBZ52257.1 - 2.2e-06 27.5 12.3 0.14 12.1 0.0 7.1 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_6 PF13174.1 CBZ52257.1 - 2.3e-06 27.6 1.2 5.7 7.6 0.0 7.5 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_7 PF13176.1 CBZ52257.1 - 5.8e-05 22.5 1.2 0.1 12.4 0.1 5.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.23 CBZ52257.1 - 0.00021 20.7 1.1 0.03 13.9 0.1 4.7 5 0 0 5 5 5 1 Tetratricopeptide repeat ChAPs PF09295.5 CBZ52257.1 - 0.0021 16.9 8.2 0.51 9.0 0.2 4.2 2 1 2 4 4 4 2 ChAPs (Chs5p-Arf1p-binding proteins) Suf PF05843.9 CBZ52257.1 - 0.0024 17.6 3.3 4.1 7.0 0.0 4.8 5 1 1 6 6 5 1 Suppressor of forked protein (Suf) TPR_9 PF13371.1 CBZ52257.1 - 0.0064 16.3 9.5 3 7.7 0.1 6.2 5 1 2 7 7 7 1 Tetratricopeptide repeat DUF1426 PF07234.6 CBZ52257.1 - 0.12 12.0 0.7 7.4 6.3 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1426) OsmC PF02566.14 CBZ52257.1 - 0.14 12.3 2.1 11 6.2 0.1 3.8 3 1 0 3 3 3 0 OsmC-like protein TPR_10 PF13374.1 CBZ52257.1 - 4.4 7.3 6.1 9.1 6.3 0.2 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF416 PF04222.7 CBZ52258.1 - 0.00093 18.3 0.5 0.00093 18.3 0.4 1.9 1 1 1 2 2 2 1 Protein of unknown function (DUF416) DUF745 PF05335.8 CBZ52258.1 - 0.016 14.7 9.3 0.022 14.2 6.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF745) DUF771 PF05595.6 CBZ52258.1 - 0.029 14.2 0.4 0.11 12.4 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF771) DUF3847 PF12958.2 CBZ52258.1 - 1.8 8.3 7.1 15 5.4 1.6 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3847) DUF676 PF05057.9 CBZ52259.1 - 0.0024 17.1 0.0 1.8 7.7 0.0 2.3 2 0 0 2 2 2 2 Putative serine esterase (DUF676) Lipase_3 PF01764.20 CBZ52259.1 - 0.23 11.0 0.0 0.69 9.5 0.0 1.7 2 0 0 2 2 2 0 Lipase (class 3) RRM_1 PF00076.17 CBZ52261.1 - 9.9e-22 76.3 0.1 1.8e-21 75.5 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) U1snRNP70_N PF12220.3 CBZ52261.1 - 1.1e-16 60.9 2.0 1.1e-16 60.9 1.4 2.4 2 0 0 2 2 2 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RRM_6 PF14259.1 CBZ52261.1 - 2.1e-16 59.6 0.0 3.5e-16 58.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBZ52261.1 - 1.6e-09 37.4 0.0 2.8e-09 36.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 CBZ52261.1 - 0.044 13.6 0.1 0.11 12.3 0.1 1.7 1 0 0 1 1 1 0 RNA binding motif Auts2 PF15336.1 CBZ52261.1 - 7.9 6.4 8.9 3.6 7.5 3.8 1.9 2 0 0 2 2 2 0 Autism susceptibility gene 2 protein DUF155 PF02582.9 CBZ52264.1 - 6.2e-31 107.6 0.1 3e-30 105.4 0.1 1.9 1 1 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 Capsid_NCLDV PF04451.7 CBZ52264.1 - 0.24 10.3 0.0 5.7 5.8 0.0 2.2 2 0 0 2 2 2 0 Large eukaryotic DNA virus major capsid protein Sec7_N PF12783.2 CBZ52266.1 - 1.3e-11 44.2 0.1 1.3e-11 44.2 0.1 3.0 3 0 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal Methuselah_N PF06652.7 CBZ52266.1 - 9.2 5.7 1.6 16 5.0 1.1 1.2 1 0 0 1 1 1 0 Methuselah N-terminus Glyoxalase_2 PF12681.2 CBZ52268.1 - 3.1e-08 34.1 0.0 0.00017 22.1 0.0 3.0 3 0 0 3 3 3 2 Glyoxalase-like domain Glyoxalase PF00903.20 CBZ52268.1 - 2.7e-07 30.6 0.0 7.7e-05 22.6 0.0 2.8 3 1 0 3 3 3 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyco_transf_28 PF03033.15 CBZ52269.1 - 0.022 14.5 0.4 0.044 13.5 0.3 1.5 1 0 0 1 1 1 0 Glycosyltransferase family 28 N-terminal domain TUSC2 PF15000.1 CBZ52270.1 - 0.0068 16.4 0.0 0.012 15.6 0.0 1.4 1 0 0 1 1 1 1 Tumour suppressor candidate 2 MvaI_BcnI PF15515.1 CBZ52271.1 - 1.6 8.7 6.0 25 4.7 0.4 3.1 3 0 0 3 3 3 0 MvaI/BcnI restriction endonuclease family Gly_transf_sug PF04488.10 CBZ52273.1 - 0.018 15.4 0.1 0.15 12.4 0.0 2.3 1 1 0 1 1 1 0 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.2 CBZ52273.1 - 0.019 13.4 0.1 0.56 8.6 0.0 2.2 2 0 0 2 2 2 0 TcdA/TcdB catalytic glycosyltransferase domain Ebola_NP PF05505.7 CBZ52274.1 - 2.7 5.9 3.6 4.1 5.3 2.5 1.1 1 0 0 1 1 1 0 Ebola nucleoprotein PGAP1 PF07819.8 CBZ52275.1 - 3.6e-15 56.1 0.0 6e-15 55.4 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_5 PF12695.2 CBZ52275.1 - 0.00033 20.4 0.0 0.0021 17.8 0.0 2.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF1469 PF07332.6 CBZ52275.1 - 0.023 14.4 0.1 0.023 14.4 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1469) Anoctamin PF04547.7 CBZ52275.1 - 0.58 8.7 0.4 1.1 7.7 0.3 1.4 1 0 0 1 1 1 0 Calcium-activated chloride channel Use1 PF09753.4 CBZ52276.1 - 0.059 12.8 0.0 0.083 12.3 0.0 1.2 1 0 0 1 1 1 0 Membrane fusion protein Use1 SF3b1 PF08920.5 CBZ52278.1 - 1.1e-35 122.8 7.3 5.4e-29 101.0 0.1 3.8 2 1 1 3 3 3 2 Splicing factor 3B subunit 1 HEAT_2 PF13646.1 CBZ52278.1 - 2.1e-13 50.3 8.0 0.0077 16.4 0.0 7.7 5 2 3 8 8 8 4 HEAT repeats HEAT_EZ PF13513.1 CBZ52278.1 - 4.6e-09 36.5 5.5 0.23 12.0 0.0 8.6 9 1 1 10 10 10 2 HEAT-like repeat HEAT PF02985.17 CBZ52278.1 - 1.3e-07 31.0 12.8 1.1 9.4 0.1 9.3 11 0 0 11 11 9 2 HEAT repeat Adaptin_N PF01602.15 CBZ52278.1 - 5e-06 25.1 0.9 0.11 10.7 0.0 3.4 1 1 1 3 3 3 2 Adaptin N terminal region UME PF08064.8 CBZ52278.1 - 5.7e-06 26.2 0.7 0.21 11.5 0.0 4.7 4 0 0 4 4 4 1 UME (NUC010) domain Arm PF00514.18 CBZ52278.1 - 0.00015 21.4 0.4 30 4.6 0.0 5.3 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat CTD PF12815.2 CBZ52278.1 - 0.001 19.4 12.2 0.001 19.4 8.5 4.3 2 1 2 4 4 4 2 Spt5 C-terminal nonapeptide repeat binding Spt4 ParcG PF10274.4 CBZ52278.1 - 0.0016 18.3 1.8 7.7 6.3 0.0 4.4 2 1 1 4 4 4 1 Parkin co-regulated protein Vac14_Fab1_bd PF12755.2 CBZ52278.1 - 0.005 17.1 0.2 37 4.7 0.0 5.6 6 0 0 6 6 6 0 Vacuolar 14 Fab1-binding region DUF2435 PF10363.4 CBZ52278.1 - 0.0083 16.0 7.4 1.6 8.6 0.0 4.2 5 0 0 5 5 5 2 Protein of unknown function (DUF2435) CRM1_C PF08767.6 CBZ52278.1 - 0.19 10.6 0.1 0.67 8.8 0.0 2.0 2 1 0 2 2 2 0 CRM1 C terminal Cnd3 PF12719.2 CBZ52278.1 - 0.48 9.3 2.3 32 3.3 0.0 3.2 3 0 0 3 3 3 0 Nuclear condensing complex subunits, C-term domain His_Phos_1 PF00300.17 CBZ52279.1 - 1.2e-13 51.4 2.9 2e-09 37.7 1.9 3.2 2 1 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) ketoacyl-synt PF00109.21 CBZ52282.1 - 0 1600.3 17.6 1.5e-75 253.9 0.0 9.1 7 1 1 8 8 8 8 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 CBZ52282.1 - 3.7e-257 836.5 28.4 4e-38 129.9 0.4 7.6 7 0 0 7 7 7 7 Beta-ketoacyl synthase, C-terminal domain Acyl_transf_1 PF00698.16 CBZ52282.1 - 1.9e-248 822.5 42.7 5.1e-50 170.5 2.2 5.3 5 0 0 5 5 5 5 Acyl transferase domain PP-binding PF00550.20 CBZ52282.1 - 1.2e-77 256.0 11.8 8.5e-12 45.1 0.0 7.1 6 0 0 6 6 6 6 Phosphopantetheine attachment site KR PF08659.5 CBZ52282.1 - 1.9e-70 236.2 0.7 1.3e-48 165.0 0.0 3.2 2 0 0 2 2 2 2 KR domain adh_short PF00106.20 CBZ52282.1 - 2.3e-52 177.2 2.1 6.1e-38 130.3 0.1 4.7 4 0 0 4 4 4 2 short chain dehydrogenase NAD_binding_4 PF07993.7 CBZ52282.1 - 1.9e-29 102.3 0.0 3.8e-28 98.0 0.0 2.8 3 0 0 3 3 3 1 Male sterility protein Thiolase_N PF00108.18 CBZ52282.1 - 8.4e-14 51.1 16.7 0.0058 15.6 0.0 6.4 6 0 0 6 6 6 6 Thiolase, N-terminal domain ATP-grasp_5 PF13549.1 CBZ52282.1 - 2.9e-07 29.9 1.1 19 4.3 0.0 6.1 6 0 0 6 6 6 0 ATP-grasp domain Abhydrolase_6 PF12697.2 CBZ52282.1 - 3.6e-07 30.3 12.1 4.6 7.0 0.1 6.2 5 0 0 5 5 5 3 Alpha/beta hydrolase family DUF4330 PF14221.1 CBZ52282.1 - 5.1e-05 23.1 6.8 6.6 6.5 0.0 5.4 5 0 0 5 5 5 2 Domain of unknown function (DUF4330) ACP_syn_III PF08545.5 CBZ52282.1 - 0.00063 19.3 30.3 0.11 12.1 0.1 7.7 7 0 0 7 7 7 3 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III FAE1_CUT1_RppA PF08392.7 CBZ52282.1 - 0.0042 16.2 9.6 0.91 8.5 0.4 3.8 3 0 0 3 3 3 2 FAE1/Type III polyketide synthase-like protein Epimerase PF01370.16 CBZ52282.1 - 0.0046 16.4 0.6 4.1 6.7 0.2 2.9 2 1 0 2 2 2 2 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 CBZ52282.1 - 0.037 12.9 0.0 0.71 8.7 0.0 2.3 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein DNA_gyraseB_C PF00986.16 CBZ52282.1 - 0.045 13.4 0.0 2.1e+02 1.7 0.0 5.1 5 0 0 5 5 5 0 DNA gyrase B subunit, carboxyl terminus TPR_11 PF13414.1 CBZ52282.1 - 0.053 13.1 4.5 58 3.4 0.0 4.9 5 0 0 5 5 5 0 TPR repeat Abhydrolase_1 PF00561.15 CBZ52282.1 - 0.059 12.9 0.1 3.3e+02 0.6 0.0 4.8 5 0 0 5 5 5 0 alpha/beta hydrolase fold DUF4056 PF13265.1 CBZ52282.1 - 4.3 6.2 4.7 1.9e+02 0.8 0.0 4.3 5 0 0 5 5 5 0 Protein of unknown function (DUF4056) UPF0227 PF05728.7 CBZ52282.1 - 4.4 6.9 0.4 2.1e+02 1.5 0.0 3.6 5 0 0 5 5 5 0 Uncharacterised protein family (UPF0227) DUF4426 PF14467.1 CBZ52282.1 - 9 6.1 0.0 88 2.9 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4426) AMP-binding PF00501.23 CBZ52283.1 - 1.8e-05 23.3 0.4 0.043 12.2 0.0 3.9 4 1 0 4 4 4 2 AMP-binding enzyme DUF367 PF04034.8 CBZ52284.1 - 1e-36 125.3 0.0 1.4e-36 124.8 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF367) RLI PF04068.10 CBZ52284.1 - 7.4e-08 31.8 0.9 1.5e-07 30.9 0.6 1.5 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI DUF2580 PF10824.3 CBZ52285.1 - 0.61 10.4 4.5 0.14 12.5 0.9 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2580) Antimicrobial_2 PF08023.7 CBZ52285.1 - 1.6 9.1 5.6 11 6.3 0.2 2.5 2 0 0 2 2 2 0 Frog antimicrobial peptide PNPase PF03726.9 CBZ52285.1 - 3.8 7.8 6.2 1 9.6 0.1 2.6 2 1 2 4 4 4 0 Polyribonucleotide nucleotidyltransferase, RNA binding domain YbaB_DNA_bd PF02575.11 CBZ52285.1 - 4 7.3 7.4 1.5 8.7 0.3 2.8 2 1 1 3 3 3 0 YbaB/EbfC DNA-binding family WD40 PF00400.27 CBZ52287.1 - 7.9e-10 38.2 0.1 0.00011 21.9 0.0 5.0 5 0 0 5 5 5 3 WD domain, G-beta repeat DUF1168 PF06658.7 CBZ52289.1 - 0.0041 16.6 29.6 0.0041 16.6 20.5 2.6 2 1 0 2 2 2 1 Protein of unknown function (DUF1168) AAA_23 PF13476.1 CBZ52289.1 - 0.16 12.3 18.4 0.19 12.0 12.7 1.1 1 0 0 1 1 1 0 AAA domain SprA-related PF12118.3 CBZ52289.1 - 0.18 11.1 24.7 0.23 10.7 17.1 1.3 1 0 0 1 1 1 0 SprA-related family TFIIF_alpha PF05793.7 CBZ52289.1 - 1.5 7.1 52.8 1.7 6.9 35.9 1.4 1 1 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) ATP-synt_B PF00430.13 CBZ52289.1 - 1.7 8.4 16.9 2.9 7.6 11.7 1.3 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) DUF2229 PF09989.4 CBZ52289.1 - 8.4 5.7 7.7 12 5.2 5.3 1.3 1 0 0 1 1 1 0 CoA enzyme activase uncharacterised domain (DUF2229) Hex_IIIa PF02455.11 CBZ52289.1 - 8.8 4.8 18.0 10 4.7 12.4 1.1 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) DnaJ PF00226.26 CBZ52290.1 - 2e-14 53.0 3.1 2.3e-14 52.8 1.1 1.9 2 0 0 2 2 2 1 DnaJ domain Thioredoxin_6 PF13848.1 CBZ52290.1 - 8.6e-12 45.2 0.0 3.8e-08 33.3 0.0 2.6 2 1 1 3 3 3 2 Thioredoxin-like domain Thioredoxin PF00085.15 CBZ52290.1 - 1.6e-10 40.6 0.0 8.3e-10 38.2 0.0 2.2 3 0 0 3 3 3 1 Thioredoxin cNMP_binding PF00027.24 CBZ52291.1 - 1.5e-19 69.5 0.0 3.1e-15 55.7 0.0 2.7 3 0 0 3 3 3 2 Cyclic nucleotide-binding domain HMGL-like PF00682.14 CBZ52292.1 - 6.8e-40 137.2 1.6 2.9e-39 135.1 0.9 2.0 2 0 0 2 2 2 1 HMGL-like TAF4 PF05236.9 CBZ52292.1 - 0.022 14.0 0.5 0.042 13.1 0.4 1.3 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family cNMP_binding PF00027.24 CBZ52293.1 - 2.3e-18 65.7 0.0 3.7e-06 26.6 0.0 4.4 4 0 0 4 4 4 4 Cyclic nucleotide-binding domain FixH PF05751.6 CBZ52293.1 - 0.65 9.7 1.3 40 4.0 0.4 2.4 2 0 0 2 2 2 0 FixH DUF2946 PF11162.3 CBZ52294.1 - 0.031 14.5 1.6 0.43 10.7 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2946) cEGF PF12662.2 CBZ52295.1 - 0.0001 21.8 59.3 3.6 7.3 0.5 12.9 13 0 0 13 13 13 7 Complement Clr-like EGF-like TIL PF01826.12 CBZ52295.1 - 0.0054 16.8 53.5 1.9 8.6 0.3 12.1 9 4 1 10 10 10 3 Trypsin Inhibitor like cysteine rich domain Antistasin PF02822.9 CBZ52295.1 - 0.04 14.2 0.1 0.04 14.2 0.1 11.2 14 0 0 14 14 14 0 Antistasin family SH3_5 PF08460.5 CBZ52295.1 - 0.066 13.1 0.0 26 4.8 0.0 4.5 6 0 0 6 6 6 0 Bacterial SH3 domain Prok-E2_C PF14459.1 CBZ52295.1 - 0.073 13.1 2.7 12 5.9 0.1 3.7 3 0 0 3 3 3 0 Prokaryotic E2 family C EB PF01683.13 CBZ52295.1 - 0.35 10.9 34.2 0.91 9.6 0.2 9.9 5 4 2 7 7 7 0 EB module EGF_MSP1_1 PF12946.2 CBZ52295.1 - 3.7 7.4 25.1 3 7.6 0.7 8.2 6 2 1 7 7 7 0 MSP1 EGF domain 1 Exo_endo_phos PF03372.18 CBZ52296.1 - 3.1e-16 60.0 1.0 2e-14 54.1 0.7 3.3 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family ATP-synt_ab PF00006.20 CBZ52297.1 - 9.5e-71 237.7 0.0 1.3e-70 237.2 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 CBZ52297.1 - 6.4e-23 81.3 0.1 1.4e-22 80.3 0.1 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 CBZ52297.1 - 3.4e-17 62.4 4.3 1.2e-16 60.6 3.0 2.0 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.5 CBZ52297.1 - 2.4e-07 30.5 2.2 5.6e-07 29.3 1.5 1.6 1 0 0 1 1 1 1 HAS barrel domain Claudin_2 PF13903.1 CBZ52298.1 - 0.44 10.2 4.9 0.2 11.3 0.1 2.2 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction 2OG-FeII_Oxy_2 PF13532.1 CBZ52299.1 - 7.3e-09 35.7 0.0 1e-08 35.2 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily MPC PF03650.8 CBZ52301.1 - 5.9e-30 103.6 0.6 7.6e-30 103.3 0.4 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0041) MtN3_slv PF03083.11 CBZ52301.1 - 0.008 16.0 0.1 0.011 15.5 0.1 1.2 1 0 0 1 1 1 1 Sugar efflux transporter for intercellular exchange DUF1379 PF07126.7 CBZ52301.1 - 0.079 12.3 0.1 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1379) Peptidase_S8 PF00082.17 CBZ52302.1 - 4.6e-37 127.6 2.3 1.1e-36 126.4 1.6 1.6 1 0 0 1 1 1 1 Subtilase family MMR_HSR1 PF01926.18 CBZ52303.1 - 4e-15 55.8 0.0 3.2e-13 49.6 0.0 2.4 2 0 0 2 2 2 1 50S ribosome-binding GTPase TrmE_N PF10396.4 CBZ52303.1 - 7.2e-08 32.3 0.5 0.0015 18.5 0.2 2.6 2 0 0 2 2 2 2 GTP-binding protein TrmE N-terminus Dynamin_N PF00350.18 CBZ52303.1 - 9.9e-05 22.2 1.2 0.00017 21.4 0.0 2.0 2 0 0 2 2 2 1 Dynamin family FeoB_N PF02421.13 CBZ52303.1 - 0.0012 18.1 0.0 0.0026 17.0 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B Miro PF08477.8 CBZ52303.1 - 0.0053 17.2 0.0 0.078 13.4 0.0 2.4 2 0 0 2 2 2 1 Miro-like protein ABC_tran PF00005.22 CBZ52303.1 - 0.023 14.9 0.0 0.095 13.0 0.0 2.0 1 0 0 1 1 1 0 ABC transporter DUF258 PF03193.11 CBZ52303.1 - 0.031 13.4 0.0 0.068 12.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Arf PF00025.16 CBZ52303.1 - 0.23 10.6 0.0 0.6 9.3 0.0 1.6 1 0 0 1 1 1 0 ADP-ribosylation factor family Minor_capsid_2 PF11114.3 CBZ52304.1 - 0.041 13.7 0.4 0.1 12.4 0.3 1.7 1 0 0 1 1 1 0 Minor capsid protein Pkinase PF00069.20 CBZ52308.1 - 1.7e-42 145.3 0.0 9.5e-21 74.1 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ52308.1 - 2e-12 46.7 0.1 4.7e-07 29.1 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase eIF2A PF08662.6 CBZ52310.1 - 1.4e-47 161.9 0.0 2e-40 138.5 0.0 3.7 4 0 0 4 4 4 2 Eukaryotic translation initiation factor eIF2A GYF PF02213.11 CBZ52310.1 - 6.6e-14 51.2 0.0 1.3e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 GYF domain zf-RING_2 PF13639.1 CBZ52311.1 - 3.6e-09 36.2 5.7 3.6e-09 36.2 3.9 2.7 2 0 0 2 2 2 1 Ring finger domain PHD PF00628.24 CBZ52311.1 - 4.7e-09 35.8 8.9 4.7e-09 35.8 6.1 3.1 3 0 0 3 3 3 1 PHD-finger zf-C3HC4 PF00097.20 CBZ52311.1 - 1.5e-07 30.9 6.0 1.5e-07 30.9 4.1 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 CBZ52311.1 - 8.1e-07 29.0 3.0 2.5e-06 27.4 2.1 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 CBZ52311.1 - 4.1e-06 26.4 6.0 4.1e-06 26.4 4.2 2.5 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 CBZ52311.1 - 1.8e-05 24.2 2.9 1.8e-05 24.2 2.0 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CBZ52311.1 - 0.00062 19.7 6.7 0.00062 19.7 4.6 2.8 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 CBZ52311.1 - 0.0061 16.1 6.6 0.019 14.5 4.5 2.0 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain Baculo_IE-1 PF05290.6 CBZ52311.1 - 0.46 10.2 2.9 0.89 9.2 2.0 1.4 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-Apc11 PF12861.2 CBZ52311.1 - 6.7 6.6 11.6 0.32 10.8 1.9 2.4 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger MACPF PF01823.14 CBZ52312.1 - 1e-46 159.3 2.3 7.7e-46 156.4 0.0 2.5 2 0 0 2 2 2 1 MAC/Perforin domain CWC25 PF12542.3 CBZ52313.1 - 2.1e-15 56.9 0.0 2.1e-15 56.9 0.0 4.7 3 2 0 3 3 3 1 Pre-mRNA splicing factor Pkinase PF00069.20 CBZ52314.1 - 2.3e-29 102.3 0.0 1.6e-12 47.1 0.0 3.3 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ52314.1 - 9.4e-18 64.2 0.0 7.9e-11 41.5 0.0 2.6 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 CBZ52314.1 - 0.0039 16.1 0.0 0.083 11.8 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 CBZ52314.1 - 0.033 13.2 0.0 0.061 12.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family YTH PF04146.10 CBZ52316.1 - 5.7e-33 113.4 0.0 8.2e-33 112.9 0.0 1.2 1 0 0 1 1 1 1 YT521-B-like domain SNARE PF05739.14 CBZ52317.1 - 4.6e-10 39.0 2.3 4.6e-10 39.0 1.6 2.5 3 0 0 3 3 3 1 SNARE domain Syntaxin_2 PF14523.1 CBZ52317.1 - 0.002 18.1 3.4 0.002 18.1 2.3 2.2 2 0 0 2 2 2 1 Syntaxin-like protein EamA PF00892.15 CBZ52317.1 - 0.05 13.6 0.0 0.079 13.0 0.0 1.2 1 0 0 1 1 1 0 EamA-like transporter family DUF892 PF05974.7 CBZ52317.1 - 0.075 12.8 6.3 0.47 10.2 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF892) Peptidase_S8 PF00082.17 CBZ52318.1 - 1.1e-51 175.6 1.7 1.9e-51 174.9 1.2 1.4 1 0 0 1 1 1 1 Subtilase family Presenilin PF01080.12 CBZ52319.1 - 1.5e-19 70.1 14.2 4.5e-17 61.9 7.0 3.4 2 1 0 2 2 2 1 Presenilin Ribosomal_L2_C PF03947.13 CBZ52320.1 - 4.1e-42 143.0 2.9 6.1e-42 142.4 2.0 1.3 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 CBZ52320.1 - 7.8e-18 64.2 0.2 1.8e-17 63.0 0.1 1.7 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain TATR PF03430.8 CBZ52321.1 - 0.19 10.3 5.5 0.21 10.1 3.8 1.1 1 0 0 1 1 1 0 Trans-activating transcriptional regulator DDOST_48kD PF03345.9 CBZ52324.1 - 2.8e-73 246.8 0.0 2.1e-67 227.5 0.0 2.1 2 0 0 2 2 2 2 Oligosaccharyltransferase 48 kDa subunit beta HMG_box_2 PF09011.5 CBZ52326.1 - 1.2e-11 44.7 13.6 6e-08 32.9 2.0 2.6 2 0 0 2 2 2 2 HMG-box domain HMG_box PF00505.14 CBZ52326.1 - 2.9e-11 43.4 7.1 1.3e-07 31.8 0.6 2.7 2 0 0 2 2 2 2 HMG (high mobility group) box Myb_DNA-binding PF00249.26 CBZ52326.1 - 1.1e-05 25.3 0.0 2.9e-05 24.0 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain ABC1 PF03109.11 CBZ52327.1 - 8.1e-32 109.7 0.0 1.7e-31 108.6 0.0 1.6 1 0 0 1 1 1 1 ABC1 family APH PF01636.18 CBZ52327.1 - 0.068 12.8 5.1 8.3 6.0 0.8 3.4 1 1 1 3 3 3 0 Phosphotransferase enzyme family Herpes_LMP1 PF05297.6 CBZ52328.1 - 0.25 10.2 1.7 11 4.7 0.1 2.2 2 0 0 2 2 2 0 Herpesvirus latent membrane protein 1 (LMP1) RabGAP-TBC PF00566.13 CBZ52329.1 - 7.3e-46 156.3 0.1 1.3e-45 155.4 0.1 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain FBA PF04300.8 CBZ52330.1 - 7.4 6.5 7.9 1.1 9.1 1.9 2.1 2 1 0 2 2 2 0 F-box associated region Isy1 PF06246.7 CBZ52333.1 - 1.6e-77 260.3 7.0 1.9e-77 260.1 4.9 1.1 1 0 0 1 1 1 1 Isy1-like splicing family CtIP_N PF10482.4 CBZ52334.1 - 0.62 9.8 5.0 0.18 11.5 0.9 2.0 2 0 0 2 2 2 0 Tumour-suppressor protein CtIP N-terminal domain DEAD PF00270.24 CBZ52335.1 - 1.9e-13 50.2 0.0 2.1e-07 30.6 0.0 2.3 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.26 CBZ52335.1 - 1.9e-13 50.0 0.0 3.8e-13 49.0 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain FHA PF00498.21 CBZ52336.1 - 2.3e-17 62.8 0.0 2e-07 30.9 0.0 2.5 2 0 0 2 2 2 2 FHA domain zf-C3HC4_4 PF15227.1 CBZ52336.1 - 2.3e-08 33.7 9.4 5.4e-08 32.5 6.5 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.1 CBZ52336.1 - 1.2e-06 28.1 6.8 3e-06 26.7 4.7 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CBZ52336.1 - 1.6e-06 27.8 10.3 4.3e-06 26.4 7.1 1.8 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 CBZ52336.1 - 3.3e-06 27.0 10.2 8.9e-06 25.6 7.1 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CBZ52336.1 - 6.7e-06 25.6 9.2 6.7e-06 25.6 6.4 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBZ52336.1 - 4.4e-05 23.1 8.9 0.00011 21.7 6.2 1.8 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_6 PF14835.1 CBZ52336.1 - 6.7e-05 22.5 4.5 0.00014 21.5 3.1 1.6 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_UBOX PF13445.1 CBZ52336.1 - 0.0012 18.5 5.7 0.0026 17.4 4.0 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.2 CBZ52336.1 - 0.013 15.6 1.9 0.031 14.3 1.3 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger Prok-RING_4 PF14447.1 CBZ52336.1 - 0.022 14.2 2.1 0.068 12.7 1.5 1.9 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 U-box PF04564.10 CBZ52336.1 - 0.028 14.3 0.2 0.18 11.7 0.0 2.4 2 0 0 2 2 2 0 U-box domain zf-RING_4 PF14570.1 CBZ52336.1 - 0.18 11.4 6.0 0.4 10.2 4.2 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Dicty_REP PF05086.7 CBZ52337.1 - 1.5 6.5 1.6 2.4 5.8 1.1 1.3 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Kelch_3 PF13415.1 CBZ52338.1 - 1.2e-21 76.2 14.0 3.1e-06 27.1 0.3 7.1 8 0 0 8 8 8 4 Galactose oxidase, central domain Kelch_4 PF13418.1 CBZ52338.1 - 6.1e-20 70.7 14.2 0.00034 20.3 0.3 6.1 4 1 1 5 5 5 5 Galactose oxidase, central domain Kelch_5 PF13854.1 CBZ52338.1 - 6.3e-18 64.3 6.0 0.0003 20.6 0.0 5.3 5 0 0 5 5 5 4 Kelch motif Kelch_6 PF13964.1 CBZ52338.1 - 1.7e-15 56.4 8.8 6.5e-05 22.9 0.0 5.6 4 1 1 5 5 5 3 Kelch motif Kelch_1 PF01344.20 CBZ52338.1 - 2.4e-12 46.1 12.5 5.8e-05 22.5 0.0 6.1 6 0 0 6 6 6 2 Kelch motif Kelch_2 PF07646.10 CBZ52338.1 - 2.1e-07 30.4 8.9 0.00039 20.0 0.0 5.1 5 0 0 5 5 5 1 Kelch motif DUF972 PF06156.8 CBZ52338.1 - 0.013 15.8 1.1 0.025 14.9 0.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF972) Leu_zip PF15294.1 CBZ52338.1 - 0.023 13.8 1.3 0.032 13.3 0.9 1.1 1 0 0 1 1 1 0 Leucine zipper bZIP_1 PF00170.16 CBZ52338.1 - 0.033 14.1 1.5 0.084 12.8 1.1 1.7 1 0 0 1 1 1 0 bZIP transcription factor GAS PF13851.1 CBZ52338.1 - 0.12 11.5 2.1 0.21 10.7 1.5 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding FlaC_arch PF05377.6 CBZ52338.1 - 0.27 11.1 1.9 1.6 8.6 0.6 2.3 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) DivIC PF04977.10 CBZ52338.1 - 0.37 10.2 1.9 0.85 9.1 1.3 1.5 1 0 0 1 1 1 0 Septum formation initiator OHA PF14418.1 CBZ52339.1 - 2.7e-11 42.8 0.0 4.1e-10 39.0 0.0 2.3 2 0 0 2 2 2 1 OST-HTH Associated domain NatB_MDM20 PF09797.4 CBZ52343.1 - 0.0031 16.3 0.2 0.0063 15.2 0.0 1.5 2 0 0 2 2 2 1 N-acetyltransferase B complex (NatB) non catalytic subunit eIF-3c_N PF05470.7 CBZ52343.1 - 0.18 9.8 0.0 0.26 9.3 0.0 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus VKOR PF07884.9 CBZ52345.1 - 6.1e-13 48.8 7.8 8.9e-13 48.2 5.4 1.3 1 0 0 1 1 1 1 Vitamin K epoxide reductase family AP2 PF00847.15 CBZ52346.1 - 5e-08 32.9 3.2 5.9e-06 26.3 0.2 2.5 2 0 0 2 2 2 2 AP2 domain Got1 PF04178.7 CBZ52347.1 - 1.3e-22 80.0 8.6 1.8e-22 79.6 6.0 1.2 1 0 0 1 1 1 1 Got1/Sft2-like family 7tm_3 PF00003.17 CBZ52347.1 - 0.013 14.9 2.6 0.013 14.9 1.8 1.4 2 0 0 2 2 2 0 7 transmembrane sweet-taste receptor of 3 GCPR AP2 PF00847.15 CBZ52348.1 - 4.5e-07 29.9 1.9 6.9e-07 29.3 0.7 1.9 2 0 0 2 2 2 1 AP2 domain ACDC PF14733.1 CBZ52348.1 - 0.33 11.1 0.0 0.62 10.2 0.0 1.3 1 0 0 1 1 1 0 AP2-coincident C-terminal Chorein_N PF12624.2 CBZ52349.1 - 2.2e-18 65.9 0.0 4.1e-18 65.0 0.0 1.4 1 0 0 1 1 1 1 N-terminal region of Chorein, a TM vesicle-mediated sorter Nuc-transf PF10127.4 CBZ52349.1 - 2.6 7.3 1.9 4.8 6.4 1.3 1.3 1 0 0 1 1 1 0 Predicted nucleotidyltransferase DUF3536 PF12055.3 CBZ52349.1 - 7.6 5.6 0.0 13 4.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3536) Ribosomal_L44 PF00935.14 CBZ52350.1 - 7.7e-34 115.5 12.0 9.9e-34 115.1 8.3 1.1 1 0 0 1 1 1 1 Ribosomal protein L44 MRP-S28 PF10213.4 CBZ52351.1 - 1.9e-07 31.1 0.0 4e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit protein EXOSC1 PF10447.4 CBZ52352.1 - 6.5e-25 86.9 0.2 1.3e-24 85.9 0.1 1.5 1 0 0 1 1 1 1 Exosome component EXOSC1/CSL4 ECR1_N PF14382.1 CBZ52352.1 - 2.2e-14 52.4 0.1 5.3e-14 51.2 0.1 1.7 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region S-layer PF07752.6 CBZ52352.1 - 0.14 11.3 0.0 0.2 10.8 0.0 1.1 1 0 0 1 1 1 0 S-layer protein NAD_binding_4 PF07993.7 CBZ52355.1 - 3.5e-59 199.7 0.0 5.3e-59 199.1 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Acyltransferase PF01553.16 CBZ52355.1 - 1.8e-10 40.3 0.0 3.4e-10 39.4 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase Epimerase PF01370.16 CBZ52355.1 - 2.9e-10 39.9 0.0 9.3e-10 38.3 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 CBZ52355.1 - 1.7e-09 36.7 0.1 3.1e-07 29.3 0.1 3.0 2 1 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 CBZ52355.1 - 0.024 13.5 0.2 0.43 9.4 0.2 2.2 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein DUF763 PF05559.6 CBZ52355.1 - 0.075 11.9 0.0 0.14 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF763) RRM_1 PF00076.17 CBZ52356.1 - 1.3e-52 175.2 0.0 4.5e-17 61.4 0.0 4.5 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBZ52356.1 - 1.1e-36 124.6 0.3 9e-13 48.0 0.0 4.2 3 1 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBZ52356.1 - 1.8e-27 94.9 0.0 3.3e-08 33.2 0.0 4.4 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1866 PF08952.6 CBZ52356.1 - 0.024 14.1 0.0 0.057 12.9 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1866) Limkain-b1 PF11608.3 CBZ52356.1 - 0.028 14.1 0.5 3.1 7.6 0.0 3.3 3 0 0 3 3 3 0 Limkain b1 RNA_bind PF08675.6 CBZ52356.1 - 0.29 11.1 0.0 2.3 8.2 0.0 2.4 3 0 0 3 3 3 0 RNA binding domain cNMP_binding PF00027.24 CBZ52357.1 - 6.6e-05 22.6 0.0 0.0014 18.3 0.0 2.4 2 0 0 2 2 2 1 Cyclic nucleotide-binding domain zf-RING_2 PF13639.1 CBZ52358.1 - 6.2e-09 35.5 11.8 6.2e-09 35.5 8.2 2.3 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 CBZ52358.1 - 6.5e-06 26.0 18.3 1.1e-05 25.3 9.6 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CBZ52358.1 - 1.5e-05 24.5 12.2 1.5e-05 24.5 8.4 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CBZ52358.1 - 4.1e-05 23.1 12.7 4.1e-05 23.1 8.8 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) LON PF02190.11 CBZ52358.1 - 0.00023 20.9 0.0 0.00098 18.8 0.0 1.9 2 1 0 2 2 2 1 ATP-dependent protease La (LON) domain zf-RING_5 PF14634.1 CBZ52358.1 - 0.00054 19.6 14.1 0.00054 19.6 9.8 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 CBZ52358.1 - 0.0088 15.8 16.8 0.0088 15.8 11.6 2.3 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.1 CBZ52358.1 - 0.1 12.1 8.5 0.22 11.0 5.9 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 U-box PF04564.10 CBZ52358.1 - 0.13 12.2 0.1 0.33 10.9 0.0 1.7 2 0 0 2 2 2 0 U-box domain zf-rbx1 PF12678.2 CBZ52358.1 - 4.6 7.4 11.9 0.61 10.2 4.7 2.2 2 1 0 2 2 2 0 RING-H2 zinc finger AlaDh_PNT_N PF05222.10 CBZ52359.1 - 3e-38 130.8 0.1 8.6e-38 129.4 0.0 1.8 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, N-terminal domain AlaDh_PNT_C PF01262.16 CBZ52359.1 - 3.1e-29 101.7 7.6 7.8e-17 61.3 0.1 2.9 2 1 1 3 3 3 2 Alanine dehydrogenase/PNT, C-terminal domain Shikimate_DH PF01488.15 CBZ52359.1 - 0.0023 18.0 0.1 0.0078 16.3 0.1 1.9 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.1 CBZ52359.1 - 0.0055 16.9 0.1 0.019 15.2 0.0 1.9 2 0 0 2 2 2 1 Putative NAD(P)-binding 2-Hacid_dh_C PF02826.14 CBZ52359.1 - 0.049 12.7 1.1 5.5 6.0 0.0 2.5 1 1 1 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox PF00070.22 CBZ52359.1 - 0.051 13.9 0.0 0.15 12.4 0.0 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_N PF05222.10 CBZ52360.1 - 3e-38 130.8 0.1 8.6e-38 129.4 0.0 1.8 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, N-terminal domain AlaDh_PNT_C PF01262.16 CBZ52360.1 - 3.1e-29 101.7 7.6 7.8e-17 61.3 0.1 2.9 2 1 1 3 3 3 2 Alanine dehydrogenase/PNT, C-terminal domain Shikimate_DH PF01488.15 CBZ52360.1 - 0.0023 18.0 0.1 0.0078 16.3 0.1 1.9 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.1 CBZ52360.1 - 0.0055 16.9 0.1 0.019 15.2 0.0 1.9 2 0 0 2 2 2 1 Putative NAD(P)-binding 2-Hacid_dh_C PF02826.14 CBZ52360.1 - 0.049 12.7 1.1 5.5 6.0 0.0 2.5 1 1 1 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox PF00070.22 CBZ52360.1 - 0.051 13.9 0.0 0.15 12.4 0.0 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GN3L_Grn1 PF08701.6 CBZ52361.1 - 1e-20 73.4 6.5 1e-20 73.4 4.5 3.0 3 1 0 3 3 2 1 GNL3L/Grn1 putative GTPase MMR_HSR1 PF01926.18 CBZ52361.1 - 9.5e-17 61.0 0.5 1.6e-13 50.5 0.0 2.7 3 0 0 3 3 3 2 50S ribosome-binding GTPase FeoB_N PF02421.13 CBZ52361.1 - 1.7e-09 37.1 0.0 5.2e-06 25.8 0.0 2.4 2 0 0 2 2 2 2 Ferrous iron transport protein B GTP_EFTU PF00009.22 CBZ52361.1 - 2.7e-05 23.7 0.3 0.18 11.2 0.0 3.8 3 1 0 3 3 3 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 CBZ52361.1 - 0.00035 20.4 0.9 1.7 8.4 0.1 3.5 3 0 0 3 3 3 2 Dynamin family DUF258 PF03193.11 CBZ52361.1 - 0.0077 15.4 0.1 0.021 14.0 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function, DUF258 Miro PF08477.8 CBZ52361.1 - 0.009 16.5 0.0 0.87 10.0 0.0 2.5 2 0 0 2 2 2 1 Miro-like protein cobW PF02492.14 CBZ52361.1 - 0.082 12.3 0.3 6.2 6.2 0.0 2.7 2 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain SRPRB PF09439.5 CBZ52361.1 - 0.1 11.7 0.4 0.32 10.1 0.0 1.9 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit ArgK PF03308.11 CBZ52361.1 - 0.11 11.2 1.6 0.14 10.9 0.1 2.0 2 0 0 2 2 2 0 ArgK protein AAA_16 PF13191.1 CBZ52361.1 - 0.3 11.0 8.7 0.46 10.4 0.0 3.0 3 0 0 3 3 3 0 AAA ATPase domain Kelch_5 PF13854.1 CBZ52362.1 - 3.3e-07 30.1 0.1 0.00079 19.3 0.0 4.0 3 0 0 3 3 3 2 Kelch motif Kelch_4 PF13418.1 CBZ52362.1 - 2.7e-06 27.0 6.1 1.9e-05 24.3 0.1 4.1 4 0 0 4 4 4 1 Galactose oxidase, central domain Kelch_1 PF01344.20 CBZ52362.1 - 0.027 13.9 0.0 2 7.9 0.0 3.2 3 0 0 3 3 3 0 Kelch motif DUF3228 PF11539.3 CBZ52363.1 - 2.2e-68 229.2 0.0 2.5e-68 229.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3228) APC10 PF03256.11 CBZ52364.1 - 9.8e-37 126.4 0.0 1.6e-36 125.7 0.0 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) F5_F8_type_C PF00754.20 CBZ52364.1 - 0.031 14.0 0.0 0.031 14.0 0.0 1.9 2 0 0 2 2 2 0 F5/8 type C domain UPF0054 PF02130.12 CBZ52365.1 - 1.4e-09 37.4 0.1 2.5e-09 36.5 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized protein family UPF0054 ACPS PF01648.15 CBZ52365.1 - 1.7e-08 34.2 0.0 1e-07 31.7 0.0 2.3 3 0 0 3 3 3 1 4'-phosphopantetheinyl transferase superfamily MIP-T3 PF10243.4 CBZ52366.1 - 1.4e-09 37.0 59.0 1.7e-09 36.7 40.9 1.2 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 Mitofilin PF09731.4 CBZ52366.1 - 0.00018 20.3 32.8 0.00036 19.3 22.8 1.6 1 0 0 1 1 1 1 Mitochondrial inner membrane protein Mem_trans PF03547.13 CBZ52366.1 - 0.058 11.6 4.8 0.069 11.4 3.4 1.4 1 1 0 1 1 1 0 Membrane transport protein SAPS PF04499.10 CBZ52366.1 - 0.12 10.9 19.9 0.17 10.4 13.8 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF2207 PF09972.4 CBZ52366.1 - 0.36 9.3 0.0 0.36 9.3 0.0 2.7 2 1 0 2 2 2 0 Predicted membrane protein (DUF2207) MotB_plug PF13677.1 CBZ52366.1 - 2.3 7.6 0.0 2.3 7.6 0.0 4.2 2 1 0 2 2 2 0 Membrane MotB of proton-channel complex MotA/MotB LMBR1 PF04791.11 CBZ52366.1 - 9.9 4.6 15.4 3.9 5.9 9.1 1.5 2 0 0 2 2 2 0 LMBR1-like membrane protein CRAL_TRIO PF00650.15 CBZ52367.1 - 1.5e-25 89.5 0.0 2e-25 89.1 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 CBZ52367.1 - 8.7e-05 22.5 0.2 0.00042 20.4 0.0 2.1 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain DnaJ PF00226.26 CBZ52368.1 - 1.2e-16 60.1 1.2 1.3e-15 56.8 0.2 3.0 2 1 0 2 2 2 1 DnaJ domain Myb_DNA-binding PF00249.26 CBZ52368.1 - 2.4e-16 59.5 5.1 1.7e-07 31.1 0.0 3.7 4 0 0 4 4 4 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 CBZ52368.1 - 1.1e-07 31.8 8.6 0.00099 19.1 0.0 3.8 3 0 0 3 3 3 2 Myb-like DNA-binding domain LETM1 PF07766.8 CBZ52368.1 - 0.47 9.4 8.5 0.99 8.3 5.9 1.5 1 0 0 1 1 1 0 LETM1-like protein Prefoldin PF02996.12 CBZ52370.1 - 8.1e-12 44.8 2.4 1.6e-10 40.6 0.0 2.3 2 0 0 2 2 2 2 Prefoldin subunit Prefoldin_2 PF01920.15 CBZ52370.1 - 0.65 9.7 0.1 0.65 9.7 0.0 2.9 2 1 1 3 3 3 0 Prefoldin subunit Mg_trans_NIPA PF05653.9 CBZ52372.1 - 1e-19 70.6 11.3 1.5e-19 70.0 7.8 1.2 1 0 0 1 1 1 1 Magnesium transporter NIPA EmrE PF13536.1 CBZ52372.1 - 1.3e-05 25.3 6.4 1.3e-05 25.3 4.5 3.1 2 1 1 3 3 3 1 Multidrug resistance efflux transporter EamA PF00892.15 CBZ52372.1 - 7e-05 22.8 5.0 7e-05 22.8 3.5 3.4 2 1 1 3 3 3 2 EamA-like transporter family UPF0546 PF10639.4 CBZ52372.1 - 0.018 14.8 6.8 0.39 10.5 0.8 2.5 2 0 0 2 2 2 0 Uncharacterised protein family UPF0546 Alkyl_sulf_dimr PF14863.1 CBZ52373.1 - 1.5e-31 109.5 0.1 3e-31 108.5 0.1 1.5 1 0 0 1 1 1 1 Alkyl sulfatase dimerisation Lactamase_B PF00753.22 CBZ52373.1 - 1.4e-14 54.2 0.0 4.3e-14 52.6 0.0 1.8 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 CBZ52373.1 - 0.0035 16.9 0.0 0.0076 15.8 0.0 1.6 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Atg14 PF10186.4 CBZ52374.1 - 0.034 13.0 23.4 0.35 9.7 7.1 2.6 2 1 1 3 3 3 0 UV radiation resistance protein and autophagy-related subunit 14 TPR_MLP1_2 PF07926.7 CBZ52374.1 - 0.039 13.7 11.9 0.37 10.5 4.7 2.3 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Gp58 PF07902.6 CBZ52374.1 - 0.059 11.5 1.0 0.079 11.1 0.7 1.1 1 0 0 1 1 1 0 gp58-like protein DUF972 PF06156.8 CBZ52374.1 - 0.086 13.1 10.9 0.38 11.1 4.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF972) Laminin_II PF06009.7 CBZ52374.1 - 0.15 11.7 9.7 0.14 11.9 3.5 2.1 2 0 0 2 2 2 0 Laminin Domain II HAUS6_N PF14661.1 CBZ52374.1 - 0.17 11.1 8.3 0.17 11.2 1.1 2.1 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus IncA PF04156.9 CBZ52374.1 - 0.33 10.5 21.4 0.2 11.2 8.6 2.3 2 0 0 2 2 2 0 IncA protein Spc7 PF08317.6 CBZ52374.1 - 0.34 9.5 9.2 0.059 12.0 1.2 2.2 2 0 0 2 2 2 0 Spc7 kinetochore protein DUF3153 PF11353.3 CBZ52374.1 - 0.34 10.2 5.9 0.31 10.4 1.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3153) Myosin_tail_1 PF01576.14 CBZ52374.1 - 0.41 8.2 19.2 0.022 12.4 6.5 2.0 2 0 0 2 2 2 0 Myosin tail Exonuc_VII_L PF02601.10 CBZ52374.1 - 0.43 9.7 15.3 0.18 10.9 0.3 2.1 1 1 1 2 2 2 0 Exonuclease VII, large subunit Prominin PF05478.6 CBZ52374.1 - 0.96 6.8 5.4 0.077 10.5 0.6 1.3 2 0 0 2 2 2 0 Prominin Phage_GP20 PF06810.6 CBZ52374.1 - 1.4 8.3 11.6 0.36 10.2 3.9 2.1 2 0 0 2 2 2 0 Phage minor structural protein GP20 OmpH PF03938.9 CBZ52374.1 - 1.8 8.4 15.1 1.1 9.1 3.4 2.3 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Macoilin PF09726.4 CBZ52374.1 - 1.9 6.6 9.8 2.5 6.2 6.8 1.1 1 0 0 1 1 1 0 Transmembrane protein APG6 PF04111.7 CBZ52374.1 - 2.1 7.3 16.2 0.098 11.6 3.7 2.1 2 0 0 2 2 2 0 Autophagy protein Apg6 ADIP PF11559.3 CBZ52374.1 - 2.5 7.9 21.9 0.081 12.8 8.4 2.3 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding DUF342 PF03961.8 CBZ52374.1 - 2.7 6.2 5.2 0.71 8.2 1.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF342) DUF1664 PF07889.7 CBZ52374.1 - 3.1 7.6 5.3 0.73 9.6 1.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Viral_P18 PF04521.8 CBZ52374.1 - 3.3 7.1 9.3 5.9 6.3 0.3 2.6 2 1 0 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein CENP-H PF05837.7 CBZ52374.1 - 5.4 7.2 15.6 2 8.6 5.3 2.3 2 0 0 2 2 2 0 Centromere protein H (CENP-H) Mnd1 PF03962.10 CBZ52374.1 - 8.4 6.0 13.7 0.82 9.3 3.1 2.2 2 0 0 2 2 2 0 Mnd1 family ATG16 PF08614.6 CBZ52374.1 - 8.8 6.1 20.9 16 5.2 9.3 2.7 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) zf-UBR PF02207.15 CBZ52375.1 - 7.8e-17 60.7 14.4 2.3e-16 59.2 10.0 1.9 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) Phage_gp49_66 PF13876.1 CBZ52375.1 - 0.94 9.5 0.1 1.8 8.6 0.0 1.4 1 0 0 1 1 1 0 Phage protein (N4 Gp49/phage Sf6 gene 66) family DUF4366 PF14283.1 CBZ52376.1 - 0.23 10.8 3.6 0.14 11.5 0.1 2.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4366) DUF726 PF05277.7 CBZ52377.1 - 9.5e-79 264.7 3.2 9.8e-48 162.7 0.1 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF726) Abhydrolase_6 PF12697.2 CBZ52377.1 - 0.031 14.1 0.1 0.031 14.1 0.1 2.8 1 1 0 2 2 2 0 Alpha/beta hydrolase family VirJ PF06057.6 CBZ52377.1 - 0.078 12.7 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) LCAT PF02450.10 CBZ52377.1 - 0.23 10.3 0.0 0.37 9.7 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase SR-25 PF10500.4 CBZ52379.1 - 0.0031 17.0 32.6 0.0031 17.0 22.6 1.7 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein AA_permease_N PF08403.5 CBZ52379.1 - 0.063 12.6 0.1 0.063 12.6 0.1 2.2 2 1 0 2 2 2 0 Amino acid permease N-terminal TATR PF03430.8 CBZ52379.1 - 0.085 11.4 8.7 0.11 11.1 6.0 1.1 1 0 0 1 1 1 0 Trans-activating transcriptional regulator BRF1 PF07741.8 CBZ52379.1 - 0.11 12.7 17.9 1.4 9.1 0.3 2.8 3 0 0 3 3 3 0 Brf1-like TBP-binding domain FLO_LFY PF01698.11 CBZ52379.1 - 0.38 9.5 14.2 0.57 8.9 9.8 1.2 1 0 0 1 1 1 0 Floricaula / Leafy protein Herpes_DNAp_acc PF04929.7 CBZ52379.1 - 0.52 9.2 12.9 0.71 8.7 8.9 1.2 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Zip PF02535.17 CBZ52379.1 - 0.72 8.8 3.8 0.8 8.6 2.6 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Hid1 PF12722.2 CBZ52379.1 - 1.1 6.8 8.5 1 6.9 5.9 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Neur_chan_memb PF02932.11 CBZ52379.1 - 2 8.2 7.0 3.2 7.5 4.8 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region GAGA_bind PF06217.7 CBZ52379.1 - 3.2 7.6 14.8 6.1 6.7 10.3 1.4 1 0 0 1 1 1 0 GAGA binding protein-like family CLP_protease PF00574.18 CBZ52380.1 - 3e-10 40.0 0.0 0.0029 17.2 0.0 3.1 3 0 0 3 3 3 3 Clp protease Rad17 PF03215.10 CBZ52381.1 - 7e-10 38.2 0.0 0.029 13.0 0.0 5.3 5 1 0 5 5 5 3 Rad17 cell cycle checkpoint protein RNA12 PF10443.4 CBZ52381.1 - 0.88 7.9 0.1 1.3 7.3 0.0 1.1 1 0 0 1 1 1 0 RNA12 protein USP7_ICP0_bdg PF12436.3 CBZ52381.1 - 0.94 8.6 0.0 1.5 7.9 0.0 1.2 1 0 0 1 1 1 0 ICP0-binding domain of Ubiquitin-specific protease 7 Med3 PF11593.3 CBZ52381.1 - 7.3 5.7 3.3 15 4.7 2.3 1.4 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DUF2229 PF09989.4 CBZ52382.1 - 0.098 12.1 0.9 0.17 11.3 0.6 1.3 1 0 0 1 1 1 0 CoA enzyme activase uncharacterised domain (DUF2229) IFT57 PF10498.4 CBZ52382.1 - 0.15 10.7 2.2 0.23 10.1 1.5 1.2 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 DEAD PF00270.24 CBZ52385.1 - 3e-38 130.9 0.0 4.9e-38 130.2 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CBZ52385.1 - 2.2e-15 56.2 0.0 4.6e-15 55.2 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain LRR_6 PF13516.1 CBZ52386.1 - 2.5e-05 23.8 1.4 11 6.4 0.2 5.2 5 0 0 5 5 5 2 Leucine Rich repeat LRR_1 PF00560.28 CBZ52386.1 - 0.0068 16.2 5.3 2.3 8.5 0.3 4.3 4 0 0 4 4 4 2 Leucine Rich Repeat LRR_4 PF12799.2 CBZ52386.1 - 0.25 11.0 3.0 20 4.9 0.0 3.6 3 1 0 3 3 3 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CBZ52386.1 - 0.76 9.5 2.8 27 4.6 0.1 3.6 4 0 0 4 4 4 0 Leucine rich repeat LRR_7 PF13504.1 CBZ52386.1 - 6.2 7.4 6.7 3.1 8.3 0.5 3.6 4 0 0 4 4 4 0 Leucine rich repeat Ank_2 PF12796.2 CBZ52387.1 - 3.7e-22 78.4 1.9 5e-07 29.9 0.1 5.6 6 0 0 6 6 6 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 CBZ52387.1 - 1.5e-21 76.3 4.0 1.5e-05 25.3 0.0 7.1 7 0 0 7 7 7 3 Ankyrin repeats (many copies) Ank PF00023.25 CBZ52387.1 - 2.1e-16 58.7 13.7 5.1e-06 26.0 0.2 7.2 7 0 0 7 7 7 3 Ankyrin repeat Ank_5 PF13857.1 CBZ52387.1 - 4.2e-10 39.5 11.6 0.00021 21.4 0.1 5.4 5 0 0 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 CBZ52387.1 - 3.9e-07 29.6 4.1 0.019 15.1 0.0 6.2 7 0 0 7 7 7 2 Ankyrin repeat LRR_4 PF12799.2 CBZ52387.1 - 8.4e-07 28.4 4.8 7.8e-06 25.3 0.2 3.7 3 1 1 4 4 4 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CBZ52387.1 - 3.8e-05 23.3 8.5 6.1e-05 22.6 0.9 3.1 2 1 0 2 2 2 1 Leucine rich repeat LRR_1 PF00560.28 CBZ52387.1 - 0.23 11.6 3.7 4.6 7.6 0.1 4.2 4 0 0 4 4 4 0 Leucine Rich Repeat DPM2 PF07297.7 CBZ52387.1 - 0.87 9.9 0.0 1.8 8.9 0.0 1.4 1 0 0 1 1 1 0 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) DUF4448 PF14610.1 CBZ52387.1 - 8.6 5.8 0.0 16 4.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Rep_fac-A_C PF08646.5 CBZ52388.1 - 5.9e-30 103.9 0.2 2.8e-29 101.7 0.1 2.0 2 0 0 2 2 2 1 Replication factor-A C terminal domain tRNA_anti-codon PF01336.20 CBZ52388.1 - 1.6e-08 34.2 2.0 6.1e-07 29.2 0.1 3.3 3 1 0 3 3 3 1 OB-fold nucleic acid binding domain POT1 PF02765.12 CBZ52388.1 - 0.022 14.6 0.0 0.3 10.9 0.0 2.5 3 0 0 3 3 3 0 Telomeric single stranded DNA binding POT1/CDC13 GTP-bdg_N PF13167.1 CBZ52388.1 - 0.084 13.0 0.9 2.5 8.3 0.0 2.9 2 1 1 3 3 3 0 GTP-binding GTPase N-terminal Dynein_heavy PF03028.10 CBZ52391.1 - 1.3e-243 810.2 0.0 1.3e-243 810.2 0.0 2.0 3 0 0 3 3 3 1 Dynein heavy chain and region D6 of dynein motor DHC_N1 PF08385.7 CBZ52391.1 - 1.7e-140 469.2 12.4 1.7e-140 469.2 8.6 3.3 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 1 AAA_6 PF12774.2 CBZ52391.1 - 8.7e-119 395.1 0.2 1.9e-118 394.0 0.1 1.6 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region D1 DHC_N2 PF08393.8 CBZ52391.1 - 4.7e-105 351.4 9.3 4.7e-105 351.4 6.4 5.9 5 1 0 5 5 5 1 Dynein heavy chain, N-terminal region 2 AAA_8 PF12780.2 CBZ52391.1 - 1.8e-95 318.9 0.0 4e-95 317.8 0.0 1.6 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_9 PF12781.2 CBZ52391.1 - 2.5e-70 235.8 1.6 6e-70 234.6 1.1 1.6 1 0 0 1 1 1 1 ATP-binding dynein motor region D5 AAA_7 PF12775.2 CBZ52391.1 - 3e-61 206.9 0.2 6.3e-61 205.8 0.1 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region D3 MT PF12777.2 CBZ52391.1 - 3.6e-56 190.4 20.4 3.9e-36 124.5 9.8 2.9 3 0 0 3 3 3 2 Microtubule-binding stalk of dynein motor AAA_5 PF07728.9 CBZ52391.1 - 1.4e-24 86.4 0.1 4.1e-11 42.7 0.0 5.9 5 1 0 5 5 5 3 AAA domain (dynein-related subfamily) AAA PF00004.24 CBZ52391.1 - 0.00031 20.9 0.0 0.093 12.9 0.0 4.3 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 CBZ52391.1 - 0.0043 17.8 2.1 0.34 11.7 0.0 5.3 5 0 0 5 5 5 1 AAA domain AAA_18 PF13238.1 CBZ52391.1 - 0.039 14.2 0.0 5.8 7.2 0.0 4.6 5 0 0 5 5 4 0 AAA domain RNA_helicase PF00910.17 CBZ52391.1 - 0.048 13.8 0.1 15 5.8 0.0 3.6 3 0 0 3 3 3 0 RNA helicase Mg_chelatase PF01078.16 CBZ52391.1 - 0.19 10.8 0.9 2.4 7.2 0.0 2.9 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI SIP1 PF04938.7 CBZ52392.1 - 1.3e-06 27.9 0.1 0.0038 16.5 0.0 2.6 3 0 0 3 3 3 2 Survival motor neuron (SMN) interacting protein 1 (SIP1) Citrate_synt PF00285.16 CBZ52393.1 - 3.2e-122 407.6 0.0 3.6e-122 407.5 0.0 1.0 1 0 0 1 1 1 1 Citrate synthase RRM_1 PF00076.17 CBZ52396.1 - 4.8e-17 61.3 0.1 8.1e-17 60.6 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBZ52396.1 - 8.8e-13 48.0 0.1 1.7e-12 47.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBZ52396.1 - 0.023 14.5 0.0 0.041 13.7 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SpoU_methylase PF00588.14 CBZ52397.1 - 2.5e-08 33.9 0.0 4.9e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 SpoU rRNA Methylase family ACDC PF14733.1 CBZ52398.1 - 1.6e-12 47.3 0.0 3.4e-12 46.3 0.0 1.6 1 0 0 1 1 1 1 AP2-coincident C-terminal AP2 PF00847.15 CBZ52398.1 - 1.3e-10 41.2 0.1 9.3e-06 25.7 0.2 2.6 2 0 0 2 2 2 2 AP2 domain V_ATPase_I PF01496.14 CBZ52398.1 - 8.9 4.0 0.3 13 3.4 0.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Bax1-I PF01027.15 CBZ52400.1 - 9.4e-22 77.6 25.2 4e-20 72.2 11.4 2.1 1 1 1 2 2 2 2 Inhibitor of apoptosis-promoting Bax1 SdpI PF13630.1 CBZ52400.1 - 0.0079 15.8 5.3 0.0079 15.8 3.7 2.1 2 1 0 2 2 2 1 SdpI/YhfL protein family MerC PF03203.9 CBZ52400.1 - 0.022 15.1 3.8 0.047 14.0 2.5 1.7 1 1 0 1 1 1 0 MerC mercury resistance protein DUF3611 PF12263.3 CBZ52400.1 - 0.17 11.2 8.8 0.039 13.3 3.6 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3611) Orbi_NS3 PF01616.11 CBZ52400.1 - 0.44 9.4 1.7 0.43 9.5 0.3 1.5 2 0 0 2 2 2 0 Orbivirus NS3 DUF1469 PF07332.6 CBZ52400.1 - 1.7 8.4 5.0 2.9 7.6 0.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1469) MMR_HSR1 PF01926.18 CBZ52402.1 - 2.1e-36 124.3 0.0 7.6e-18 64.5 0.0 2.7 3 0 0 3 3 2 2 50S ribosome-binding GTPase KH_dom-like PF14714.1 CBZ52402.1 - 7.6e-26 89.8 0.1 2.8e-25 88.0 0.1 2.0 2 0 0 2 2 1 1 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal FeoB_N PF02421.13 CBZ52402.1 - 2.4e-14 52.9 0.1 1.2e-06 27.8 0.0 4.0 3 1 0 3 3 3 2 Ferrous iron transport protein B GTP_EFTU PF00009.22 CBZ52402.1 - 6.1e-14 51.8 0.1 0.00072 19.0 0.0 5.4 5 1 0 5 5 5 2 Elongation factor Tu GTP binding domain Miro PF08477.8 CBZ52402.1 - 1.6e-11 44.7 0.0 0.00043 20.7 0.0 3.5 3 0 0 3 3 3 2 Miro-like protein Dynamin_N PF00350.18 CBZ52402.1 - 8e-09 35.5 0.5 0.00017 21.4 0.0 3.9 3 1 1 4 4 4 1 Dynamin family DUF258 PF03193.11 CBZ52402.1 - 3.4e-06 26.3 0.0 0.05 12.7 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AIG1 PF04548.11 CBZ52402.1 - 3.5e-06 26.2 0.0 0.078 12.0 0.0 2.3 2 0 0 2 2 2 2 AIG1 family Ras PF00071.17 CBZ52402.1 - 0.00011 21.6 0.0 0.45 9.8 0.0 3.4 3 1 0 3 3 3 2 Ras family AAA_22 PF13401.1 CBZ52402.1 - 0.00047 20.3 0.0 1.7 8.7 0.0 3.3 3 1 0 3 3 2 2 AAA domain AAA_33 PF13671.1 CBZ52402.1 - 0.00078 19.3 1.8 0.27 11.1 0.0 3.6 4 0 0 4 4 3 1 AAA domain SRPRB PF09439.5 CBZ52402.1 - 0.0011 18.2 0.0 0.36 10.0 0.0 2.5 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit ABC_tran PF00005.22 CBZ52402.1 - 0.0021 18.3 0.0 0.37 11.0 0.0 2.5 2 0 0 2 2 2 1 ABC transporter Gtr1_RagA PF04670.7 CBZ52402.1 - 0.0022 17.1 0.0 0.5 9.4 0.0 2.5 2 1 0 2 2 2 1 Gtr1/RagA G protein conserved region Septin PF00735.13 CBZ52402.1 - 0.0053 15.8 0.0 0.28 10.1 0.0 2.3 2 0 0 2 2 2 1 Septin MobB PF03205.9 CBZ52402.1 - 0.0056 16.3 0.0 1.8 8.2 0.0 2.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_17 PF13207.1 CBZ52402.1 - 0.0086 16.8 0.0 0.85 10.4 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 CBZ52402.1 - 0.0095 16.2 0.1 8.1 6.7 0.0 3.5 3 0 0 3 3 3 0 AAA domain AAA_16 PF13191.1 CBZ52402.1 - 0.012 15.5 0.7 8.2 6.3 0.0 3.4 2 1 0 2 2 2 0 AAA ATPase domain RNA_helicase PF00910.17 CBZ52402.1 - 0.013 15.6 0.0 5.5 7.2 0.0 2.4 2 0 0 2 2 2 0 RNA helicase FtsK_SpoIIIE PF01580.13 CBZ52402.1 - 0.014 14.8 0.0 0.4 10.1 0.0 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_29 PF13555.1 CBZ52402.1 - 0.02 14.3 0.0 1.9 8.0 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain cobW PF02492.14 CBZ52402.1 - 0.022 14.2 0.0 15 5.0 0.0 3.5 3 1 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain AAA_10 PF12846.2 CBZ52402.1 - 0.038 13.4 0.0 0.91 8.8 0.0 2.3 2 0 0 2 2 2 0 AAA-like domain Arf PF00025.16 CBZ52402.1 - 0.047 12.9 0.0 2.2 7.4 0.0 3.2 4 0 0 4 4 4 0 ADP-ribosylation factor family AAA_28 PF13521.1 CBZ52402.1 - 0.051 13.5 0.0 3 7.7 0.0 2.7 2 0 0 2 2 2 0 AAA domain ArgK PF03308.11 CBZ52402.1 - 0.063 12.0 0.0 5.2 5.7 0.0 2.8 2 0 0 2 2 2 0 ArgK protein GBP PF02263.14 CBZ52402.1 - 0.11 11.4 0.2 3.7 6.5 0.0 2.5 2 1 0 2 2 2 0 Guanylate-binding protein, N-terminal domain Arch_ATPase PF01637.13 CBZ52402.1 - 0.12 12.0 0.0 4 7.0 0.0 2.2 2 0 0 2 2 2 0 Archaeal ATPase AAA_24 PF13479.1 CBZ52402.1 - 0.22 11.1 0.0 15 5.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain Nop14 PF04147.7 CBZ52402.1 - 2.5 5.9 6.8 3.2 5.5 4.7 1.2 1 0 0 1 1 1 0 Nop14-like family Pkinase PF00069.20 CBZ52403.1 - 1.3e-61 208.0 0.0 2.3e-61 207.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ52403.1 - 6.3e-34 117.2 0.0 9.3e-34 116.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase DDE_Tnp_1_2 PF13586.1 CBZ52403.1 - 0.026 14.7 0.1 0.37 10.9 0.0 2.5 2 0 0 2 2 2 0 Transposase DDE domain NUC173 PF08161.7 CBZ52405.1 - 1.3e-14 54.0 0.1 3.9e-14 52.4 0.1 1.9 1 0 0 1 1 1 1 NUC173 domain DUF2435 PF10363.4 CBZ52405.1 - 0.13 12.1 0.4 0.61 10.0 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2435) V_ATPase_I PF01496.14 CBZ52406.1 - 0.16 9.7 19.8 0.24 9.2 13.7 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Fib_alpha PF08702.5 CBZ52406.1 - 0.3 11.1 19.7 0.13 12.3 8.4 2.5 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family GCV_H PF01597.14 CBZ52407.1 - 2.4e-24 85.3 0.6 3.3e-19 68.7 0.1 2.8 1 1 1 2 2 2 2 Glycine cleavage H-protein Biotin_lipoyl PF00364.17 CBZ52407.1 - 0.00042 19.8 0.1 0.00077 19.0 0.1 1.4 1 0 0 1 1 1 1 Biotin-requiring enzyme Pheromone PF08015.6 CBZ52407.1 - 1.4 9.7 7.9 14 6.5 1.1 3.7 4 0 0 4 4 4 0 Fungal mating-type pheromone Chorismate_bind PF00425.13 CBZ52411.1 - 2.8e-45 154.6 0.0 5.3e-26 91.4 0.0 2.2 1 1 1 2 2 2 2 chorismate binding enzyme GATase PF00117.23 CBZ52411.1 - 6.2e-41 139.9 0.0 8.9e-41 139.4 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 CBZ52411.1 - 5.2e-08 32.5 0.0 8.7e-08 31.8 0.0 1.3 1 0 0 1 1 1 1 Peptidase C26 Anth_synt_I_N PF04715.8 CBZ52411.1 - 2.4e-07 30.8 0.0 5.3e-07 29.7 0.0 1.6 1 0 0 1 1 1 1 Anthranilate synthase component I, N terminal region Peptidase_M14 PF00246.19 CBZ52412.1 - 5.3e-23 82.0 0.0 7.2e-23 81.5 0.0 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase DUF2817 PF10994.3 CBZ52412.1 - 0.0002 20.5 0.0 0.00023 20.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2817) BTB_2 PF02214.17 CBZ52413.1 - 8.2e-06 25.9 0.0 5.8e-05 23.2 0.0 2.1 1 1 0 1 1 1 1 BTB/POZ domain zf-CCCH PF00642.19 CBZ52413.1 - 0.00042 19.9 1.8 0.00042 19.9 1.3 3.4 2 1 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Ubiq-Cytc-red_N PF09165.5 CBZ52414.1 - 0.012 15.9 0.2 0.034 14.4 0.2 1.7 1 0 0 1 1 1 0 Ubiquinol-cytochrome c reductase 8 kDa, N-terminal ELM2 PF01448.19 CBZ52414.1 - 0.12 13.0 0.1 0.26 11.9 0.1 1.5 1 0 0 1 1 1 0 ELM2 domain Mito_carr PF00153.22 CBZ52415.1 - 7.4e-33 112.1 0.6 1.3e-18 66.4 0.0 3.7 3 1 1 4 4 4 3 Mitochondrial carrier protein Menin PF05053.8 CBZ52415.1 - 0.16 10.1 0.5 0.2 9.7 0.3 1.1 1 0 0 1 1 1 0 Menin SAP PF02037.22 CBZ52416.1 - 3.8e-16 58.1 0.1 1.7e-15 56.0 0.1 2.2 2 0 0 2 2 2 1 SAP domain HeH PF12949.2 CBZ52416.1 - 0.019 14.4 0.0 0.052 13.1 0.0 1.7 1 1 0 1 1 1 0 HeH/LEM domain DUF4351 PF14261.1 CBZ52416.1 - 0.079 12.8 0.0 0.61 10.0 0.0 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4351) ATP_bind_4 PF01902.12 CBZ52417.1 - 3.8e-32 111.4 0.0 6.7e-32 110.6 0.0 1.3 1 0 0 1 1 1 1 ATP-binding region NMD3 PF04981.8 CBZ52417.1 - 0.055 12.5 0.0 0.1 11.7 0.0 1.3 1 0 0 1 1 1 0 NMD3 family FHA PF00498.21 CBZ52418.1 - 1.8e-13 50.3 0.2 5.9e-10 39.1 0.1 2.5 2 0 0 2 2 2 2 FHA domain RINGv PF12906.2 CBZ52418.1 - 3.6e-13 49.3 6.4 7.3e-13 48.3 4.4 1.5 1 0 0 1 1 1 1 RING-variant domain FANCL_C PF11793.3 CBZ52418.1 - 0.022 14.6 3.3 0.04 13.8 2.3 1.4 1 0 0 1 1 1 0 FANCL C-terminal domain zf-RING_2 PF13639.1 CBZ52418.1 - 0.61 9.9 5.3 1.1 9.1 3.7 1.4 1 0 0 1 1 1 0 Ring finger domain C2 PF00168.25 CBZ52419.1 - 3.4e-12 46.0 0.1 8.7e-12 44.7 0.0 1.6 2 0 0 2 2 2 1 C2 domain UQ_con PF00179.21 CBZ52420.1 - 2e-44 150.4 0.0 2.4e-44 150.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme DnaJ PF00226.26 CBZ52421.1 - 4.1e-08 32.8 0.0 5.7e-08 32.3 0.0 1.2 1 0 0 1 1 1 1 DnaJ domain Pam16 PF03656.8 CBZ52421.1 - 4.1e-07 29.8 0.0 4.9e-07 29.5 0.0 1.2 1 0 0 1 1 1 1 Pam16 CtaG_Cox11 PF04442.9 CBZ52422.1 - 5.4e-50 169.1 0.0 6.7e-50 168.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 RRM_2 PF04059.7 CBZ52422.1 - 0.16 11.9 0.0 0.42 10.6 0.0 1.7 1 1 0 1 1 1 0 RNA recognition motif 2 Dus PF01207.12 CBZ52423.1 - 6.2e-57 192.7 0.0 5.7e-46 156.7 0.0 3.2 2 1 0 2 2 2 2 Dihydrouridine synthase (Dus) ThiG PF05690.9 CBZ52423.1 - 0.0061 15.6 0.0 0.012 14.7 0.0 1.4 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG DHO_dh PF01180.16 CBZ52423.1 - 0.0097 14.8 0.0 0.08 11.8 0.0 2.2 3 0 0 3 3 3 1 Dihydroorotate dehydrogenase PEP_mutase PF13714.1 CBZ52423.1 - 0.018 14.2 0.2 0.053 12.7 0.0 1.8 2 0 0 2 2 2 0 Phosphoenolpyruvate phosphomutase His_biosynth PF00977.16 CBZ52423.1 - 0.036 13.3 0.0 0.061 12.5 0.0 1.3 1 0 0 1 1 1 0 Histidine biosynthesis protein IMPDH PF00478.20 CBZ52423.1 - 0.053 12.3 0.0 0.084 11.7 0.0 1.2 1 0 0 1 1 1 0 IMP dehydrogenase / GMP reductase domain 3-alpha PF03475.9 CBZ52423.1 - 0.11 12.2 1.0 0.26 11.0 0.7 1.6 1 0 0 1 1 1 0 3-alpha domain Pkinase PF00069.20 CBZ52424.1 - 6.7e-20 71.3 0.0 2.3e-19 69.5 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Kinase-like PF14531.1 CBZ52424.1 - 6.9e-15 54.7 0.0 1.3e-14 53.8 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_Tyr PF07714.12 CBZ52424.1 - 1.2e-05 24.4 0.0 2.2e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase RRM_1 PF00076.17 CBZ52425.1 - 1.1e-48 162.6 0.1 2.6e-19 68.6 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBZ52425.1 - 5.8e-35 119.1 0.0 3.6e-13 49.2 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBZ52425.1 - 5.6e-33 112.5 0.1 3.7e-11 42.6 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 CBZ52425.1 - 0.0093 15.7 0.0 0.086 12.6 0.0 2.3 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif Glyoxalase_5 PF14696.1 CBZ52425.1 - 0.028 14.3 0.1 8 6.3 0.0 2.5 2 0 0 2 2 2 0 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal TFIIA PF03153.8 CBZ52426.1 - 0.054 13.4 7.9 0.074 12.9 5.5 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit TATR PF03430.8 CBZ52426.1 - 0.24 10.0 6.0 0.32 9.5 4.1 1.2 1 0 0 1 1 1 0 Trans-activating transcriptional regulator Paramyxo_ncap PF00973.14 CBZ52426.1 - 0.35 9.4 2.8 0.57 8.8 1.9 1.2 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Apt1 PF10351.4 CBZ52426.1 - 1.2 7.8 5.4 1.7 7.4 3.7 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain Hex_IIIa PF02455.11 CBZ52426.1 - 4.1 5.9 5.5 5.4 5.5 3.8 1.2 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) NARP1 PF12569.3 CBZ52426.1 - 6.3 5.4 9.6 10 4.7 6.6 1.3 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 RNase_PH PF01138.16 CBZ52427.1 - 6e-13 49.2 0.1 1e-12 48.4 0.1 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 CBZ52427.1 - 0.00014 21.6 0.0 0.00031 20.6 0.0 1.6 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 VP7 PF00434.13 CBZ52427.1 - 0.088 11.7 0.1 0.11 11.3 0.1 1.1 1 0 0 1 1 1 0 Glycoprotein VP7 RAP1 PF07218.6 CBZ52428.1 - 2.2 6.2 14.0 2.9 5.8 9.7 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DUF2217 PF10265.4 CBZ52428.1 - 4 6.0 7.2 7 5.2 5.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) CytochromB561_N PF09786.4 CBZ52428.1 - 5.6 5.3 13.2 9.6 4.5 9.2 1.3 1 0 0 1 1 1 0 Cytochrome B561, N terminal RNB PF00773.14 CBZ52430.1 - 6.8e-55 186.6 0.0 9.2e-35 120.4 0.0 3.8 3 1 0 3 3 3 3 RNB domain RNA_POL_M_15KD PF02150.11 CBZ52432.1 - 1.2e-11 44.1 4.5 1.2e-11 44.1 3.1 1.7 2 0 0 2 2 1 1 RNA polymerases M/15 Kd subunit TFIIS_C PF01096.13 CBZ52432.1 - 3.6e-05 23.2 3.6 0.00011 21.7 0.1 2.8 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) DZR PF12773.2 CBZ52432.1 - 0.0059 16.4 1.2 0.0059 16.4 0.8 2.2 2 0 0 2 2 2 1 Double zinc ribbon Rubredoxin PF00301.15 CBZ52432.1 - 0.012 15.4 9.4 0.97 9.3 0.1 3.9 2 1 1 3 3 3 0 Rubredoxin IBR PF01485.16 CBZ52432.1 - 0.066 13.0 3.9 1.6 8.6 0.9 2.8 3 0 0 3 3 3 0 IBR domain PHD PF00628.24 CBZ52432.1 - 0.14 11.9 6.7 9.4 6.0 2.4 3.3 3 1 0 3 3 3 0 PHD-finger GFA PF04828.9 CBZ52432.1 - 0.15 11.9 1.6 5.4 7.0 0.1 2.6 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme zf-RING_3 PF14369.1 CBZ52432.1 - 0.47 10.5 3.5 7.6 6.6 0.9 2.6 2 0 0 2 2 2 0 zinc-finger DUF2296 PF10058.4 CBZ52432.1 - 0.52 10.0 5.1 4.7 7.0 0.7 3.0 3 0 0 3 3 3 0 Predicted integral membrane metal-binding protein (DUF2296) zf-ribbon_3 PF13248.1 CBZ52432.1 - 1 8.6 4.2 2.5 7.4 0.1 3.1 3 0 0 3 3 3 0 zinc-ribbon domain zf-3CxxC PF13695.1 CBZ52432.1 - 1.6 9.0 4.6 5.7 7.2 2.1 2.6 1 1 1 2 2 2 0 Zinc-binding domain zf-TFIIB PF13453.1 CBZ52432.1 - 2.5 7.3 6.3 6.3 6.0 0.2 2.7 2 0 0 2 2 2 0 Transcription factor zinc-finger Zn_ribbon_recom PF13408.1 CBZ52432.1 - 2.6 8.3 5.6 0.36 11.1 0.4 2.0 2 1 0 2 2 2 0 Recombinase zinc beta ribbon domain Inhibitor_I53 PF11714.3 CBZ52432.1 - 7.9 6.5 13.0 0.88 9.5 0.1 3.4 2 1 1 3 3 3 0 Thrombin inhibitor Madanin DUF2387 PF09526.5 CBZ52432.1 - 9.7 6.1 8.2 0.7 9.8 0.6 2.5 2 1 0 2 2 2 0 Probable metal-binding protein (DUF2387) Peptidase_M16_C PF05193.16 CBZ52433.1 - 3.6e-37 127.8 0.0 1e-36 126.3 0.0 1.8 2 0 0 2 2 2 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 CBZ52433.1 - 3e-26 91.9 0.0 8.7e-26 90.4 0.0 1.8 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) E1-E2_ATPase PF00122.15 CBZ52435.1 - 2.6e-49 167.3 0.0 2.6e-49 167.3 0.0 2.1 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 CBZ52435.1 - 8.5e-24 85.1 0.0 5.5e-23 82.5 0.0 2.4 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 CBZ52435.1 - 2e-14 54.1 0.0 4.1e-14 53.1 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 CBZ52435.1 - 3e-14 52.2 0.0 9.1e-14 50.6 0.0 1.9 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 CBZ52435.1 - 0.00041 20.0 4.6 0.003 17.1 0.6 2.7 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 CBZ52435.1 - 0.0061 16.4 0.0 0.014 15.3 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit DUF4637 PF15470.1 CBZ52435.1 - 1.6 8.3 5.7 3.6 7.1 3.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) IF-2B PF01008.12 CBZ52436.1 - 1e-56 192.0 0.0 4.3e-56 189.9 0.0 1.8 1 1 0 1 1 1 1 Initiation factor 2 subunit family VID27 PF08553.5 CBZ52437.1 - 6.6e-53 180.1 0.2 8.4e-53 179.7 0.2 1.1 1 0 0 1 1 1 1 VID27 cytoplasmic protein Kinase-like PF14531.1 CBZ52438.1 - 7e-42 143.3 0.0 9.1e-42 142.9 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Pkinase PF00069.20 CBZ52438.1 - 2e-15 56.6 0.0 6.3e-15 55.0 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ52438.1 - 0.00075 18.6 0.0 0.0012 17.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Metallophos_2 PF12850.2 CBZ52439.1 - 5e-19 68.6 0.0 6.3e-19 68.3 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain DUF2437 PF10370.4 CBZ52439.1 - 0.017 15.4 0.0 0.044 14.1 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF2437) Metallophos PF00149.23 CBZ52439.1 - 0.6 9.4 3.4 1.7 8.0 2.4 1.8 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase IMS_C PF11799.3 CBZ52440.1 - 0.043 13.7 0.2 0.088 12.7 0.1 1.4 1 0 0 1 1 1 0 impB/mucB/samB family C-terminal domain Hum_adeno_E3A PF05393.6 CBZ52440.1 - 0.19 11.3 3.5 4.5 7.0 0.1 2.7 2 0 0 2 2 2 0 Human adenovirus early E3A glycoprotein PseudoU_synth_2 PF00849.17 CBZ52441.1 - 1.4e-18 67.2 0.0 3.1e-18 66.1 0.0 1.5 1 0 0 1 1 1 1 RNA pseudouridylate synthase Peptidase_M41 PF01434.13 CBZ52442.1 - 9.5e-60 201.6 0.0 1.3e-59 201.2 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 CBZ52442.1 - 1.6e-05 25.0 3.9 0.0088 16.2 0.2 3.0 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 CBZ52442.1 - 0.0091 15.9 0.2 0.041 13.8 0.1 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_19 PF13245.1 CBZ52442.1 - 0.026 14.2 0.2 0.089 12.5 0.1 1.9 1 0 0 1 1 1 0 Part of AAA domain AAA_5 PF07728.9 CBZ52442.1 - 0.085 12.5 0.6 0.21 11.2 0.1 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 CBZ52442.1 - 0.13 11.3 0.1 0.32 10.1 0.1 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_22 PF13401.1 CBZ52442.1 - 0.24 11.5 0.1 0.79 9.8 0.1 1.9 1 0 0 1 1 1 0 AAA domain DUF4188 PF13826.1 CBZ52444.1 - 0.056 13.5 0.0 0.077 13.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4188) PP2C PF00481.16 CBZ52445.1 - 7.4e-30 104.1 0.0 1.5e-24 86.7 0.0 2.8 3 0 0 3 3 3 2 Protein phosphatase 2C DUF1510 PF07423.6 CBZ52445.1 - 2.7 7.3 6.0 1.2 8.4 1.8 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) Nop14 PF04147.7 CBZ52445.1 - 3.1 5.6 10.6 5.7 4.7 7.3 1.3 1 0 0 1 1 1 0 Nop14-like family Leu_Phe_trans PF03588.9 CBZ52446.1 - 1.4e-23 82.8 0.3 7.5e-14 51.2 0.0 2.8 3 0 0 3 3 3 2 Leucyl/phenylalanyl-tRNA protein transferase RRN3 PF05327.6 CBZ52446.1 - 1 7.4 2.7 1.7 6.6 1.9 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 AAA_2 PF07724.9 CBZ52447.1 - 4.8e-41 140.5 0.0 1.4e-38 132.4 0.0 3.2 2 2 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA PF00004.24 CBZ52447.1 - 1.3e-22 80.4 0.0 5.3e-14 52.5 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 CBZ52447.1 - 3.2e-16 59.3 0.2 2.5e-10 40.2 0.0 3.3 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) ClpB_D2-small PF10431.4 CBZ52447.1 - 1.7e-14 53.4 0.0 6.5e-14 51.5 0.0 2.1 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_16 PF13191.1 CBZ52447.1 - 7.3e-14 52.1 2.3 1.4e-06 28.3 0.0 5.2 3 2 1 5 5 5 2 AAA ATPase domain Sigma54_activat PF00158.21 CBZ52447.1 - 5.1e-12 45.5 0.4 1.5e-07 31.0 0.0 3.2 2 1 0 2 2 2 2 Sigma-54 interaction domain AAA_22 PF13401.1 CBZ52447.1 - 1.8e-08 34.6 0.1 0.029 14.5 0.0 4.0 3 2 0 3 3 2 2 AAA domain IstB_IS21 PF01695.12 CBZ52447.1 - 6.1e-06 25.7 0.0 0.13 11.6 0.0 2.6 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_14 PF13173.1 CBZ52447.1 - 6.9e-06 25.9 0.0 0.18 11.7 0.0 2.8 2 1 0 2 2 2 2 AAA domain RuvB_N PF05496.7 CBZ52447.1 - 9.6e-06 24.8 0.1 0.31 10.0 0.0 3.4 3 0 0 3 3 3 1 Holliday junction DNA helicase ruvB N-terminus AAA_25 PF13481.1 CBZ52447.1 - 1.7e-05 24.3 0.1 0.31 10.4 0.0 3.5 3 0 0 3 3 3 2 AAA domain AAA_17 PF13207.1 CBZ52447.1 - 1.9e-05 25.4 1.0 0.3 11.8 0.0 3.6 4 1 0 4 4 2 2 AAA domain Arch_ATPase PF01637.13 CBZ52447.1 - 5.2e-05 23.0 0.0 0.016 14.8 0.0 3.5 2 1 1 3 3 3 1 Archaeal ATPase AAA_3 PF07726.6 CBZ52447.1 - 6.3e-05 22.5 0.1 0.093 12.3 0.0 3.1 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) TIP49 PF06068.8 CBZ52447.1 - 0.00018 20.3 0.5 0.012 14.3 0.0 2.8 2 0 0 2 2 2 1 TIP49 C-terminus NACHT PF05729.7 CBZ52447.1 - 0.00018 21.1 0.0 0.17 11.5 0.0 3.1 2 1 0 2 2 2 1 NACHT domain AAA_18 PF13238.1 CBZ52447.1 - 0.00037 20.8 0.0 1 9.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain DUF815 PF05673.8 CBZ52447.1 - 0.0011 17.9 0.1 1.4 7.7 0.0 3.2 3 1 1 4 4 4 1 Protein of unknown function (DUF815) AAA_28 PF13521.1 CBZ52447.1 - 0.0014 18.6 0.5 12 5.8 0.0 3.7 3 0 0 3 3 3 0 AAA domain Zeta_toxin PF06414.7 CBZ52447.1 - 0.0015 17.6 0.0 0.18 10.8 0.0 2.6 2 0 0 2 2 2 1 Zeta toxin DUF258 PF03193.11 CBZ52447.1 - 0.0018 17.4 0.1 1 8.5 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function, DUF258 RNA_helicase PF00910.17 CBZ52447.1 - 0.0019 18.3 0.0 3.5 7.8 0.0 2.8 2 0 0 2 2 2 1 RNA helicase MMR_HSR1 PF01926.18 CBZ52447.1 - 0.003 17.5 0.0 4 7.4 0.0 3.7 4 0 0 4 4 4 0 50S ribosome-binding GTPase AAA_29 PF13555.1 CBZ52447.1 - 0.0043 16.5 0.0 3.1 7.4 0.0 2.8 2 0 0 2 2 2 1 P-loop containing region of AAA domain T2SE PF00437.15 CBZ52447.1 - 0.0047 15.8 0.0 0.057 12.3 0.0 2.2 2 0 0 2 2 2 1 Type II/IV secretion system protein Mg_chelatase PF01078.16 CBZ52447.1 - 0.0058 15.8 1.4 3.9 6.5 0.2 3.4 2 2 0 2 2 2 1 Magnesium chelatase, subunit ChlI DUF87 PF01935.12 CBZ52447.1 - 0.0086 15.9 1.0 0.91 9.2 0.0 3.4 4 0 0 4 4 4 1 Domain of unknown function DUF87 AAA_19 PF13245.1 CBZ52447.1 - 0.012 15.3 0.1 1.1 9.1 0.0 3.0 2 0 0 2 2 2 0 Part of AAA domain AAA_23 PF13476.1 CBZ52447.1 - 0.022 15.0 0.5 0.16 12.2 0.0 2.4 3 0 0 3 3 3 0 AAA domain ABC_tran PF00005.22 CBZ52447.1 - 0.027 14.7 0.0 2.5 8.3 0.0 2.8 2 0 0 2 2 2 0 ABC transporter TrwB_AAD_bind PF10412.4 CBZ52447.1 - 0.031 12.9 0.0 1.6 7.2 0.0 2.5 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AAA_24 PF13479.1 CBZ52447.1 - 0.037 13.6 0.0 4.3 6.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 CBZ52447.1 - 0.038 13.4 0.0 9.8 5.5 0.0 3.4 2 1 1 3 3 3 0 AAA-like domain ResIII PF04851.10 CBZ52447.1 - 0.039 13.7 0.1 6.6 6.5 0.0 3.4 2 1 1 3 3 3 0 Type III restriction enzyme, res subunit AAA_21 PF13304.1 CBZ52447.1 - 0.046 13.6 0.5 0.92 9.4 0.0 2.6 2 1 0 2 2 2 0 AAA domain SDA1 PF05285.7 CBZ52447.1 - 0.051 12.8 5.2 0.047 12.9 1.1 2.1 2 0 0 2 2 2 0 SDA1 UPF0079 PF02367.12 CBZ52447.1 - 0.078 12.6 0.2 16 5.1 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 DNA_pol3_delta2 PF13177.1 CBZ52447.1 - 0.15 11.6 0.0 3.4 7.2 0.0 2.7 2 1 0 2 2 2 0 DNA polymerase III, delta subunit Ribophorin_I PF04597.9 CBZ52448.1 - 4.5e-61 206.6 0.0 3.1e-60 203.9 0.0 2.4 1 1 0 1 1 1 1 Ribophorin I DUF1754 PF08555.5 CBZ52448.1 - 1.9e-10 41.2 13.2 4.8e-10 39.9 9.2 1.7 1 0 0 1 1 1 1 Eukaryotic family of unknown function (DUF1754) SSrecog PF03531.9 CBZ52448.1 - 0.19 11.0 0.0 0.44 9.8 0.0 1.5 1 0 0 1 1 1 0 Structure-specific recognition protein (SSRP1) NIF PF03031.13 CBZ52449.1 - 2.1e-19 69.7 0.0 1.6e-07 31.1 0.0 3.2 3 0 0 3 3 3 3 NLI interacting factor-like phosphatase PDEase_I PF00233.14 CBZ52450.1 - 7.2e-57 192.8 1.1 1.2e-56 192.1 0.8 1.3 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase HD PF01966.17 CBZ52450.1 - 0.00028 20.9 0.1 0.00075 19.5 0.0 1.7 1 0 0 1 1 1 1 HD domain Oxidored_q1 PF00361.15 CBZ52450.1 - 0.12 11.6 5.0 0.21 10.8 3.4 1.3 1 0 0 1 1 1 0 NADH-Ubiquinone/plastoquinone (complex I), various chains tRNA-synt_2 PF00152.15 CBZ52451.1 - 2.3e-79 266.6 0.1 3.2e-79 266.1 0.1 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 CBZ52451.1 - 7.4e-09 35.3 0.9 1.5e-08 34.3 0.6 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 CBZ52451.1 - 0.00027 20.2 0.3 0.11 11.6 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) Gluconate_2-dh3 PF13618.1 CBZ52451.1 - 0.0065 16.6 1.5 0.42 10.7 0.6 2.5 2 0 0 2 2 2 1 Gluconate 2-dehydrogenase subunit 3 RRP14 PF15459.1 CBZ52451.1 - 1.9 8.5 9.0 3.9 7.6 6.3 1.5 1 0 0 1 1 1 0 60S ribosome biogenesis protein Rrp14 DUF3273 PF11677.3 CBZ52453.1 - 4.4e-84 281.8 8.6 5.1e-84 281.6 5.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3273) UPF0233 PF06781.7 CBZ52453.1 - 1.1 8.9 6.8 1.7 8.3 0.0 3.6 3 1 1 4 4 4 0 Uncharacterised protein family (UPF0233) DUF3273 PF11677.3 CBZ52454.1 - 2.7e-82 276.0 9.1 3.1e-82 275.8 6.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3273) UPF0233 PF06781.7 CBZ52454.1 - 2.2 7.9 9.2 2.6 7.7 0.3 3.9 2 1 2 4 4 4 0 Uncharacterised protein family (UPF0233) PHD PF00628.24 CBZ52455.1 - 1.9e-07 30.6 2.0 5.8e-07 29.1 1.4 1.8 1 0 0 1 1 1 1 PHD-finger Prok-RING_1 PF14446.1 CBZ52455.1 - 0.04 13.6 3.4 0.2 11.4 0.4 2.5 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 PHD_2 PF13831.1 CBZ52455.1 - 0.17 11.2 2.0 0.43 9.9 1.4 1.7 1 0 0 1 1 1 0 PHD-finger C1_1 PF00130.17 CBZ52455.1 - 1.3 8.8 2.0 1.2 8.8 0.1 1.9 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) SBDS PF01172.13 CBZ52457.1 - 4e-25 87.4 0.0 7.5e-25 86.5 0.0 1.5 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein SBDS_C PF09377.5 CBZ52457.1 - 7e-14 51.5 0.0 1.9e-13 50.2 0.0 1.7 1 1 0 1 1 1 1 SBDS protein C-terminal domain DAGK_acc PF00609.14 CBZ52458.1 - 1.5e-32 112.9 0.0 2.6e-32 112.1 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase accessory domain DAGK_cat PF00781.19 CBZ52458.1 - 1.5e-16 60.0 0.1 2.3e-13 49.7 0.0 2.6 2 1 0 2 2 2 2 Diacylglycerol kinase catalytic domain Flavi_NS4A PF01350.12 CBZ52459.1 - 0.084 12.4 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 Flavivirus non-structural protein NS4A Cep57_CLD_2 PF14197.1 CBZ52460.1 - 0.0068 16.3 0.6 0.028 14.3 0.5 1.9 2 0 0 2 2 2 1 Centrosome localisation domain of PPC89 HAP1_N PF04849.8 CBZ52460.1 - 0.0086 15.0 0.1 0.012 14.6 0.1 1.2 1 0 0 1 1 1 1 HAP1 N-terminal conserved region DUF4140 PF13600.1 CBZ52460.1 - 0.14 12.6 0.1 0.3 11.5 0.1 1.6 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) CRAL_TRIO PF00650.15 CBZ52463.1 - 1.6e-09 37.4 0.0 2.4e-06 27.1 0.0 2.2 1 1 1 2 2 2 2 CRAL/TRIO domain cEGF PF12662.2 CBZ52464.1 - 1.2e-38 130.3 77.7 1.2e-07 31.2 1.2 10.0 8 1 0 8 8 8 7 Complement Clr-like EGF-like FXa_inhibition PF14670.1 CBZ52464.1 - 3.1e-38 129.5 116.0 2.3e-12 46.8 5.1 9.4 9 1 0 9 9 9 7 Coagulation Factor Xa inhibitory site EGF_CA PF07645.10 CBZ52464.1 - 1.4e-37 127.4 113.2 1e-08 35.0 2.4 10.9 11 0 0 11 11 11 8 Calcium-binding EGF domain EGF PF00008.22 CBZ52464.1 - 2.5e-16 59.2 99.9 6.5e-05 22.7 3.3 10.6 10 2 0 10 10 10 8 EGF-like domain EGF_3 PF12947.2 CBZ52464.1 - 1.9e-08 34.1 96.9 6.5e-05 22.8 1.0 10.2 9 2 0 9 9 9 6 EGF domain hEGF PF12661.2 CBZ52464.1 - 0.17 11.9 43.8 0.94 9.6 0.7 8.7 7 0 0 7 7 7 0 Human growth factor-like EGF DUF605 PF04652.11 CBZ52465.1 - 1.1 8.5 33.5 1.7 7.9 23.2 1.2 1 0 0 1 1 1 0 Vta1 like GDI PF00996.13 CBZ52466.1 - 3.9e-205 681.2 0.0 4.5e-205 681.0 0.0 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor Cpn60_TCP1 PF00118.19 CBZ52467.1 - 1.2e-137 459.4 2.7 1.4e-137 459.2 1.9 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Methyltransf_23 PF13489.1 CBZ52468.1 - 2.3e-14 53.4 0.0 1.2e-13 51.1 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CBZ52468.1 - 1.6e-10 41.3 0.0 0.00061 20.2 0.0 2.9 3 0 0 3 3 3 2 Methyltransferase domain Methyltransf_18 PF12847.2 CBZ52468.1 - 2.5e-08 34.4 0.0 5.6e-05 23.6 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.7 CBZ52468.1 - 1.4e-06 28.6 0.0 0.028 14.8 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_26 PF13659.1 CBZ52468.1 - 2.5e-05 24.3 0.0 0.00011 22.1 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Myc_N PF01056.13 CBZ52468.1 - 8.3e-05 21.9 6.9 8.3e-05 21.9 4.8 1.5 2 0 0 2 2 2 1 Myc amino-terminal region Methyltransf_25 PF13649.1 CBZ52468.1 - 8.4e-05 22.8 0.0 0.076 13.3 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_31 PF13847.1 CBZ52468.1 - 0.00018 21.1 0.0 0.012 15.2 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_2 PF00891.13 CBZ52468.1 - 0.0002 20.6 0.0 0.0022 17.2 0.0 2.3 2 0 0 2 2 2 1 O-methyltransferase MTS PF05175.9 CBZ52468.1 - 0.00095 18.5 0.0 0.002 17.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain BNIP2 PF12496.3 CBZ52468.1 - 0.027 14.6 3.8 2.2 8.4 0.2 2.4 2 0 0 2 2 2 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 Methyltransf_4 PF02390.12 CBZ52468.1 - 0.03 13.3 0.0 0.068 12.2 0.0 1.6 2 0 0 2 2 2 0 Putative methyltransferase NNMT_PNMT_TEMT PF01234.12 CBZ52468.1 - 0.056 12.4 0.0 0.1 11.5 0.0 1.3 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family Ribosomal_L21p PF00829.16 CBZ52469.1 - 1.5e-13 50.6 0.1 4e-13 49.2 0.0 1.7 2 0 0 2 2 2 1 Ribosomal prokaryotic L21 protein Pro_dh PF01619.13 CBZ52470.1 - 2e-52 178.1 0.0 7e-32 110.6 0.0 2.7 2 1 0 2 2 2 2 Proline dehydrogenase Peptidase_M22 PF00814.20 CBZ52471.1 - 3.2e-71 239.9 0.2 1.2e-51 175.7 0.1 3.1 2 1 1 3 3 3 3 Glycoprotease family Ham1p_like PF01725.11 CBZ52472.1 - 1.9e-49 167.5 0.0 2.4e-49 167.3 0.0 1.0 1 0 0 1 1 1 1 Ham1 family 2TM PF13239.1 CBZ52473.1 - 0.094 12.7 3.7 2.1 8.4 1.6 2.5 2 0 0 2 2 2 0 2TM domain WD40 PF00400.27 CBZ52474.1 - 5.1e-15 54.6 15.5 5.5e-05 22.8 0.1 8.2 9 0 0 9 9 9 4 WD domain, G-beta repeat RAP PF08373.5 CBZ52476.1 - 9.4e-08 31.7 0.9 5.3e-05 22.9 0.1 2.4 2 0 0 2 2 2 2 RAP domain FAST_1 PF06743.10 CBZ52476.1 - 0.14 11.8 0.7 4 7.2 0.0 3.2 3 0 0 3 3 3 0 FAST kinase-like protein, subdomain 1 Hist_deacetyl PF00850.14 CBZ52477.1 - 9.4e-51 172.9 0.0 8.6e-43 146.7 0.0 2.2 1 1 1 2 2 2 2 Histone deacetylase domain Ank PF00023.25 CBZ52477.1 - 1.1e-14 53.4 3.0 7.9e-07 28.5 0.0 3.9 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.2 CBZ52477.1 - 3.3e-13 49.7 0.0 2.8e-06 27.5 0.0 3.2 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 CBZ52477.1 - 3.4e-11 43.3 4.2 2.2e-06 28.0 0.1 3.9 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 CBZ52477.1 - 7.6e-10 38.0 0.5 0.0013 18.7 0.0 4.1 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 CBZ52477.1 - 1.3e-06 28.4 10.0 0.011 15.9 0.0 5.6 4 2 2 6 6 6 2 Ankyrin repeats (many copies) NDK PF00334.14 CBZ52479.1 - 6e-36 123.2 0.0 6.1e-12 45.4 0.0 3.2 3 0 0 3 3 3 3 Nucleoside diphosphate kinase Tub PF01167.13 CBZ52481.1 - 8.6e-17 60.9 0.0 7.1e-16 57.9 0.0 2.3 3 0 0 3 3 3 1 Tub family DUF4554 PF15091.1 CBZ52482.1 - 0.41 9.3 1.6 0.84 8.3 1.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4554) Prp19_bind PF06991.6 CBZ52483.1 - 1.2 8.3 9.5 2.1 7.5 6.6 1.4 1 0 0 1 1 1 0 Splicing factor, Prp19-binding domain ABC1 PF03109.11 CBZ52484.1 - 1.4e-31 108.9 0.1 2.6e-31 108.0 0.0 1.4 1 0 0 1 1 1 1 ABC1 family APH PF01636.18 CBZ52484.1 - 0.0038 16.9 2.6 0.0063 16.2 0.1 2.3 2 0 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 CBZ52484.1 - 0.3 10.4 0.2 0.68 9.2 0.0 1.6 2 0 0 2 2 2 0 RIO1 family ECH PF00378.15 CBZ52485.1 - 3.2e-44 150.8 0.0 3.1e-24 85.4 0.0 3.2 3 0 0 3 3 3 3 Enoyl-CoA hydratase/isomerase family PH PF00169.24 CBZ52486.1 - 1e-08 35.3 0.0 1 9.5 0.0 5.6 3 2 1 4 4 4 4 PH domain ATPgrasp_YheCD PF14398.1 CBZ52487.1 - 0.015 14.1 0.3 0.015 14.1 0.2 1.5 2 0 0 2 2 2 0 YheC/D like ATP-grasp Mucin PF01456.12 CBZ52487.1 - 0.13 12.0 51.9 0.033 13.9 33.9 1.5 2 0 0 2 2 2 0 Mucin-like glycoprotein Herpes_UL74 PF07982.7 CBZ52487.1 - 3.2 6.3 17.4 4.7 5.7 12.0 1.2 1 0 0 1 1 1 0 Herpes UL74 glycoproteins NST1 PF13945.1 CBZ52487.1 - 5.7 6.9 6.7 1.6 8.7 2.1 1.8 2 0 0 2 2 2 0 Salt tolerance down-regulator DUF677 PF05055.7 CBZ52489.1 - 0.04 12.5 5.3 0.073 11.7 3.4 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF677) Leptin PF02024.10 CBZ52489.1 - 0.095 12.3 0.1 0.18 11.4 0.1 1.4 1 0 0 1 1 1 0 Leptin RAP PF08373.5 CBZ52490.1 - 0.00026 20.7 0.0 0.00049 19.8 0.0 1.3 1 0 0 1 1 1 1 RAP domain Spectrin PF00435.16 CBZ52490.1 - 0.012 15.8 1.7 0.029 14.6 1.2 1.6 1 0 0 1 1 1 0 Spectrin repeat Nucleoplasmin PF03066.10 CBZ52491.1 - 4.3 6.8 7.9 9.1 5.7 5.5 1.5 1 0 0 1 1 1 0 Nucleoplasmin DUF3260 PF11658.3 CBZ52491.1 - 8.1 4.4 0.2 14 3.6 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3260) Cytochrome-c551 PF10643.4 CBZ52492.1 - 0.0087 15.3 1.2 0.01 15.1 0.3 1.5 1 1 0 1 1 1 1 Photosystem P840 reaction-centre cytochrome c-551 PARP PF00644.15 CBZ52494.1 - 2.7e-11 43.3 0.0 2.6e-07 30.2 0.0 3.6 2 2 0 2 2 2 2 Poly(ADP-ribose) polymerase catalytic domain TPR_11 PF13414.1 CBZ52495.1 - 2e-06 27.3 1.8 3.7e-06 26.4 0.1 2.2 2 0 0 2 2 2 1 TPR repeat HSP70 PF00012.15 CBZ52495.1 - 0.00032 18.7 1.7 0.0061 14.5 0.0 2.9 3 0 0 3 3 3 1 Hsp70 protein TPR_2 PF07719.12 CBZ52495.1 - 0.0025 17.6 0.1 0.19 11.7 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.1 CBZ52495.1 - 0.0038 17.3 0.1 0.017 15.2 0.1 2.2 1 0 0 1 1 1 1 Tetratricopeptide repeat HEPN PF05168.9 CBZ52495.1 - 0.0099 15.7 0.0 0.031 14.1 0.0 1.9 1 0 0 1 1 1 1 HEPN domain TPR_9 PF13371.1 CBZ52495.1 - 0.016 15.0 1.4 0.033 14.0 0.2 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 CBZ52495.1 - 0.1 12.4 0.3 9.2 6.2 0.0 3.6 3 1 1 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat TPR_1 PF00515.23 CBZ52495.1 - 0.1 12.2 0.0 3.1 7.5 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF2968 PF11180.3 CBZ52497.1 - 0.63 9.3 13.2 0.22 10.8 6.0 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF2968) Striatin PF08232.7 CBZ52497.1 - 3.4 7.9 10.6 0.28 11.5 3.0 2.3 2 0 0 2 2 2 0 Striatin family NAM-associated PF14303.1 CBZ52497.1 - 5 7.4 7.8 0.65 10.2 2.3 1.8 2 0 0 2 2 2 0 No apical meristem-associated C-terminal domain MORN PF02493.15 CBZ52498.1 - 2e-08 33.4 10.3 1.1e-05 24.8 1.2 3.9 3 0 0 3 3 3 3 MORN repeat zf-met PF12874.2 CBZ52498.1 - 0.15 12.2 4.8 0.27 11.4 3.3 1.4 1 0 0 1 1 1 0 Zinc-finger of C2H2 type UCR_UQCRX_QCR9 PF05365.7 CBZ52499.1 - 6.5e-07 28.8 0.5 1.1e-06 28.1 0.4 1.3 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like Ribosomal_L37 PF08561.5 CBZ52499.1 - 0.078 12.5 1.2 0.15 11.6 0.8 1.6 1 1 0 1 1 1 0 Mitochondrial ribosomal protein L37 TPR_16 PF13432.1 CBZ52500.1 - 1.7e-09 38.0 26.6 4.2e-07 30.4 2.9 5.4 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_11 PF13414.1 CBZ52500.1 - 5.3e-09 35.6 13.2 3.7e-05 23.2 0.6 4.5 5 0 0 5 5 5 2 TPR repeat TPR_19 PF14559.1 CBZ52500.1 - 9e-05 22.7 12.4 0.25 11.6 0.4 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.1 CBZ52500.1 - 0.00071 19.1 0.2 0.17 11.7 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.23 CBZ52500.1 - 0.0028 17.2 11.0 0.41 10.3 0.4 5.0 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.1 CBZ52500.1 - 0.13 12.2 18.7 0.05 13.5 0.6 5.2 7 1 1 8 8 8 0 Tetratricopeptide repeat TPR_2 PF07719.12 CBZ52500.1 - 3.1 7.9 20.5 3.4 7.7 0.6 7.2 6 1 1 7 7 7 0 Tetratricopeptide repeat DUF1510 PF07423.6 CBZ52501.1 - 0.0071 15.7 4.1 0.0088 15.4 2.8 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) Josephin PF02099.12 CBZ52501.1 - 1.3 8.6 4.8 3.2 7.3 0.7 2.1 1 1 0 2 2 2 0 Josephin WD40 PF00400.27 CBZ52502.1 - 1.4e-34 116.6 18.5 5.1e-06 26.1 0.1 6.8 7 0 0 7 7 7 6 WD domain, G-beta repeat Asp PF00026.18 CBZ52503.1 - 6.9e-76 255.5 0.0 2.7e-65 220.7 0.0 2.1 2 0 0 2 2 2 2 Eukaryotic aspartyl protease TAXi_N PF14543.1 CBZ52503.1 - 3.2e-05 23.9 0.1 7.9e-05 22.6 0.1 1.7 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 CBZ52503.1 - 0.03 14.8 0.1 3 8.3 0.0 3.2 2 1 0 2 2 2 0 Aspartyl protease TAXi_C PF14541.1 CBZ52503.1 - 0.042 13.4 0.0 0.083 12.4 0.0 1.6 1 0 0 1 1 1 0 Xylanase inhibitor C-terminal A1_Propeptide PF07966.7 CBZ52503.1 - 0.13 12.1 0.1 0.28 11.0 0.1 1.6 1 0 0 1 1 1 0 A1 Propeptide DUF4023 PF13215.1 CBZ52503.1 - 0.24 11.1 1.7 0.48 10.2 1.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4023) Ribosomal_L37 PF08561.5 CBZ52504.1 - 1.2e-13 50.4 0.0 2.2e-13 49.5 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L37 Thioredoxin PF00085.15 CBZ52506.1 - 2e-05 24.1 0.0 3.1e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_6 PF13848.1 CBZ52506.1 - 0.061 13.1 0.0 0.09 12.5 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin-like domain FHA PF00498.21 CBZ52507.1 - 5.4e-17 61.6 0.0 1.3e-16 60.4 0.0 1.7 1 0 0 1 1 1 1 FHA domain VWA PF00092.23 CBZ52508.1 - 2.1e-44 151.3 0.0 3e-44 150.8 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain TSP_1 PF00090.14 CBZ52508.1 - 7.3e-35 118.8 75.4 4.9e-08 32.9 5.2 7.7 6 2 0 6 6 6 6 Thrombospondin type 1 domain VWA_2 PF13519.1 CBZ52508.1 - 1.3e-11 44.9 0.0 2.8e-11 43.8 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.1 CBZ52508.1 - 8e-08 32.1 0.0 1.3e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_CoxE PF05762.9 CBZ52508.1 - 0.0003 20.0 0.0 0.00047 19.3 0.0 1.2 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein DUF4366 PF14283.1 CBZ52508.1 - 0.0069 15.8 0.1 0.013 14.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4366) vWA-TerF-like PF10138.4 CBZ52508.1 - 0.019 14.7 0.0 0.03 14.1 0.0 1.2 1 0 0 1 1 1 0 vWA found in TerF C terminus Cullin PF00888.17 CBZ52509.1 - 2.2e-135 452.5 0.1 8.3e-135 450.6 0.1 1.7 1 1 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 CBZ52509.1 - 1.8e-25 88.5 0.3 4.2e-25 87.3 0.2 1.7 1 0 0 1 1 1 1 Cullin protein neddylation domain Macoilin PF09726.4 CBZ52509.1 - 6.5 4.9 15.7 9.2 4.4 10.9 1.1 1 0 0 1 1 1 0 Transmembrane protein Tctex-1 PF03645.8 CBZ52511.1 - 3.3e-21 75.0 0.3 4e-21 74.7 0.2 1.1 1 0 0 1 1 1 1 Tctex-1 family NifQ PF04891.7 CBZ52512.1 - 0.09 12.9 1.9 0.17 12.0 1.3 1.5 1 0 0 1 1 1 0 NifQ Methyltransf_PK PF05891.7 CBZ52513.1 - 9.8e-71 237.5 0.0 1.2e-70 237.2 0.0 1.0 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_18 PF12847.2 CBZ52513.1 - 6.5e-06 26.6 0.0 2.1e-05 25.0 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 CBZ52513.1 - 0.00016 22.1 0.0 0.00028 21.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.13 CBZ52513.1 - 0.00017 20.8 0.0 0.00026 20.2 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_12 PF08242.7 CBZ52513.1 - 0.0011 19.4 0.0 0.0021 18.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CBZ52513.1 - 0.0029 17.3 0.0 0.0043 16.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CBZ52513.1 - 0.0033 17.7 0.1 0.0057 16.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain WD40 PF00400.27 CBZ52514.1 - 2.3e-28 97.0 10.4 2.5e-09 36.6 0.1 7.2 6 2 0 6 6 6 5 WD domain, G-beta repeat Myc_N PF01056.13 CBZ52514.1 - 0.023 13.8 5.8 0.045 12.9 4.0 1.5 1 0 0 1 1 1 0 Myc amino-terminal region Nucleoporin_N PF08801.6 CBZ52514.1 - 0.16 10.6 0.0 0.39 9.3 0.0 1.5 1 1 0 1 1 1 0 Nup133 N terminal like WD40 PF00400.27 CBZ52515.1 - 4.1e-45 150.0 17.4 2.5e-09 36.6 0.0 6.4 6 0 0 6 6 6 6 WD domain, G-beta repeat BT1 PF03092.11 CBZ52516.1 - 2.1e-59 201.3 17.3 3e-59 200.8 12.0 1.1 1 0 0 1 1 1 1 BT1 family MFS_1 PF07690.11 CBZ52516.1 - 0.0013 17.5 0.5 0.0013 17.5 0.3 4.4 2 2 2 4 4 4 3 Major Facilitator Superfamily DUF3087 PF11286.3 CBZ52516.1 - 0.19 10.9 0.2 0.42 9.8 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3087) DUF566 PF04484.7 CBZ52516.1 - 3.6 7.0 4.8 7.7 5.9 3.4 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF566) PCI PF01399.22 CBZ52517.1 - 0.0073 16.6 0.1 0.0073 16.6 0.1 3.3 3 0 0 3 3 3 1 PCI domain SNF2_N PF00176.18 CBZ52517.1 - 2 7.1 9.2 5.1 5.8 6.4 1.7 1 0 0 1 1 1 0 SNF2 family N-terminal domain DnaJ PF00226.26 CBZ52518.1 - 2.4e-14 52.7 0.1 6.3e-14 51.4 0.0 1.7 1 0 0 1 1 1 1 DnaJ domain PP2C PF00481.16 CBZ52521.1 - 3.4e-29 102.0 0.0 1.4e-28 100.0 0.0 1.8 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 CBZ52521.1 - 0.1 11.9 0.0 0.45 9.8 0.0 2.1 1 1 0 1 1 1 0 Protein phosphatase 2C SAP18 PF06487.7 CBZ52522.1 - 7.9e-30 103.1 0.0 1.2e-29 102.5 0.0 1.2 1 0 0 1 1 1 1 Sin3 associated polypeptide p18 (SAP18) Gram_pos_anchor PF00746.16 CBZ52523.1 - 0.03 14.1 0.2 0.03 14.1 0.2 1.6 2 0 0 2 2 2 0 Gram positive anchor SNARE_assoc PF09335.6 CBZ52523.1 - 0.037 14.2 0.1 0.064 13.4 0.1 1.4 1 0 0 1 1 1 0 SNARE associated Golgi protein CcmD PF04995.9 CBZ52523.1 - 0.06 13.0 0.1 0.15 11.8 0.0 1.7 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) RskA PF10099.4 CBZ52523.1 - 0.11 12.1 5.1 0.47 10.1 1.5 2.0 1 1 1 2 2 2 0 Anti-sigma-K factor rskA Chorismate_synt PF01264.16 CBZ52524.1 - 7e-115 383.2 0.0 8.9e-61 205.2 0.0 3.0 3 0 0 3 3 3 3 Chorismate synthase LAT PF15234.1 CBZ52525.1 - 0.093 12.1 0.9 0.82 9.1 0.4 2.2 2 0 0 2 2 2 0 Linker for activation of T-cells Sugar_tr PF00083.19 CBZ52526.1 - 2.2e-33 115.5 9.7 3.4e-33 114.9 6.8 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CBZ52526.1 - 4.1e-15 55.3 29.5 1.8e-14 53.2 20.5 2.1 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 CBZ52526.1 - 8.8e-06 24.1 3.4 8.8e-06 24.1 2.3 1.5 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) PHD PF00628.24 CBZ52527.1 - 6.4e-05 22.5 3.5 6.4e-05 22.5 2.4 2.5 2 0 0 2 2 2 1 PHD-finger zf-B_box PF00643.19 CBZ52531.1 - 0.00045 20.0 5.7 0.00089 19.1 4.0 1.4 1 0 0 1 1 1 1 B-box zinc finger DUF3135 PF11333.3 CBZ52531.1 - 0.11 12.6 0.1 0.24 11.5 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3135) ATP12 PF07542.6 CBZ52532.1 - 7.9e-07 29.0 0.0 0.0026 17.7 0.0 2.5 2 0 0 2 2 2 2 ATP12 chaperone protein YTH PF04146.10 CBZ52533.1 - 2.7e-36 124.2 0.0 3.6e-36 123.8 0.0 1.2 1 0 0 1 1 1 1 YT521-B-like domain zf-CCCH PF00642.19 CBZ52533.1 - 0.0023 17.5 9.8 0.42 10.3 2.8 2.8 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Ni_hydr_CYTB PF01292.15 CBZ52534.1 - 0.048 13.0 0.1 0.63 9.3 0.0 2.2 2 0 0 2 2 2 0 Prokaryotic cytochrome b561 INTS5_N PF14837.1 CBZ52534.1 - 0.064 12.6 0.5 0.14 11.5 0.3 1.6 1 0 0 1 1 1 0 Integrator complex subunit 5 N-terminus Cytochrom_B_N PF00033.14 CBZ52534.1 - 0.11 11.8 0.1 0.68 9.2 0.1 2.0 1 1 0 1 1 1 0 Cytochrome b(N-terminal)/b6/petB DUF1664 PF07889.7 CBZ52534.1 - 0.43 10.3 3.2 11 5.7 1.5 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) E1-E2_ATPase PF00122.15 CBZ52536.1 - 3.9e-41 140.5 1.9 5.4e-21 74.6 0.5 3.1 2 1 0 2 2 2 2 E1-E2 ATPase Hydrolase PF00702.21 CBZ52536.1 - 1.7e-29 103.8 0.0 4.8e-24 85.9 0.0 3.0 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase HMA PF00403.21 CBZ52536.1 - 3.1e-20 72.0 0.2 1.1e-12 47.8 0.1 2.5 2 0 0 2 2 2 2 Heavy-metal-associated domain HAD PF12710.2 CBZ52536.1 - 1.2e-14 54.9 0.0 1.3e-13 51.6 0.0 2.6 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 CBZ52536.1 - 0.024 14.2 0.2 0.041 13.4 0.1 1.2 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase RRM_3 PF08777.6 CBZ52537.1 - 0.0015 18.3 0.0 0.0068 16.2 0.0 2.1 2 0 0 2 2 2 1 RNA binding motif Nup35_RRM_2 PF14605.1 CBZ52537.1 - 0.053 13.3 0.0 2.6 7.8 0.0 2.3 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif EcsC PF12787.2 CBZ52537.1 - 0.21 10.9 3.1 0.3 10.4 2.1 1.1 1 0 0 1 1 1 0 EcsC protein family Spore_YtfJ PF09579.5 CBZ52537.1 - 0.37 10.6 2.2 0.8 9.5 0.1 2.4 2 0 0 2 2 2 0 Sporulation protein YtfJ (Spore_YtfJ) TMPIT PF07851.8 CBZ52537.1 - 6.8 5.6 4.0 9.9 5.1 2.7 1.1 1 0 0 1 1 1 0 TMPIT-like protein Pkinase PF00069.20 CBZ52538.1 - 3.1e-20 72.4 0.0 1.1e-16 60.7 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ52538.1 - 1.5e-06 27.5 0.0 2.4e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBZ52538.1 - 7.3e-05 21.8 0.0 0.00012 21.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 CBZ52538.1 - 0.088 11.8 0.0 0.16 10.9 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family ELMO_CED12 PF04727.8 CBZ52539.1 - 2.2e-34 118.4 0.2 3.7e-34 117.7 0.1 1.4 1 0 0 1 1 1 1 ELMO/CED-12 family Pam17 PF08566.5 CBZ52540.1 - 0.027 14.1 0.0 0.03 14.0 0.0 1.1 1 0 0 1 1 1 0 Mitochondrial import protein Pam17 UPF0640 PF15114.1 CBZ52540.1 - 0.33 10.4 1.8 0.87 9.1 0.3 2.2 1 1 1 2 2 2 0 Uncharacterised protein family UPF0640 Zip PF02535.17 CBZ52543.1 - 0.017 14.1 0.1 0.018 14.0 0.1 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter MRI PF15325.1 CBZ52543.1 - 5.8 7.9 6.2 14 6.6 4.3 1.7 1 0 0 1 1 1 0 Modulator of retrovirus infection SelP_N PF04592.9 CBZ52545.1 - 0.25 10.6 19.2 0.38 10.0 13.3 1.4 1 0 0 1 1 1 0 Selenoprotein P, N terminal region DUF3537 PF12056.3 CBZ52545.1 - 0.32 9.6 4.1 0.49 9.0 2.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3537) Lin-8 PF03353.10 CBZ52545.1 - 2.4 7.3 7.5 3.4 6.8 5.2 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Macoilin PF09726.4 CBZ52545.1 - 4 5.6 9.1 5 5.2 6.3 1.2 1 0 0 1 1 1 0 Transmembrane protein NTP_transf_2 PF01909.18 CBZ52546.1 - 1.9e-05 24.8 0.0 3.4e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyltransferase domain PAP_assoc PF03828.14 CBZ52546.1 - 0.011 15.7 0.0 0.026 14.4 0.0 1.7 1 0 0 1 1 1 0 Cid1 family poly A polymerase PFK PF00365.15 CBZ52548.1 - 2.9e-24 85.5 0.0 1.4e-15 57.0 0.0 2.3 2 0 0 2 2 2 2 Phosphofructokinase Hist_deacetyl PF00850.14 CBZ52549.1 - 6.8e-80 268.6 0.0 6.3e-76 255.6 0.7 3.7 2 2 0 2 2 2 2 Histone deacetylase domain IPK PF03770.11 CBZ52549.1 - 2.4e-34 118.7 0.0 5.7e-34 117.4 0.0 1.7 1 0 0 1 1 1 1 Inositol polyphosphate kinase FAM176 PF14851.1 CBZ52549.1 - 0.18 11.5 0.6 0.84 9.2 0.4 2.2 1 0 0 1 1 1 0 FAM176 family Pkinase PF00069.20 CBZ52550.1 - 1.5e-42 145.5 0.0 1.9e-42 145.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ52550.1 - 4.1e-17 62.1 0.0 6.6e-17 61.4 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBZ52550.1 - 7.8e-06 25.0 0.0 1.2e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 CBZ52550.1 - 0.031 14.0 0.0 0.054 13.2 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF3712 PF12505.3 CBZ52551.1 - 1.2e-54 183.6 0.0 5.2e-15 55.5 0.0 9.4 8 1 0 8 8 8 7 Protein of unknown function (DUF3712) LEA_2 PF03168.8 CBZ52551.1 - 4e-11 43.1 0.1 0.017 15.4 0.0 7.1 6 0 0 6 6 6 3 Late embryogenesis abundant protein DUF4014 PF13198.1 CBZ52551.1 - 6.1 7.3 1.1 12 6.4 0.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4014) Pkinase PF00069.20 CBZ52552.1 - 5.6e-67 225.6 0.0 7.1e-67 225.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ52552.1 - 5.4e-31 107.6 0.0 1.2e-30 106.5 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBZ52552.1 - 0.0038 16.2 0.0 0.0063 15.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.6 CBZ52552.1 - 0.043 12.6 0.0 0.066 12.0 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 SOBP PF15279.1 CBZ52552.1 - 4 7.7 15.9 0.28 11.5 7.6 1.6 2 0 0 2 2 2 0 Sine oculis-binding protein DUF605 PF04652.11 CBZ52552.1 - 4.6 6.5 21.0 7 5.9 14.6 1.2 1 0 0 1 1 1 0 Vta1 like DUF566 PF04484.7 CBZ52552.1 - 4.7 6.6 28.6 7.1 6.0 19.9 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF566) Apt1 PF10351.4 CBZ52552.1 - 9.5 4.9 20.2 15 4.2 14.0 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain PolyA_pol_RNAbd PF12627.2 CBZ52553.1 - 0.0069 15.9 0.0 0.025 14.1 0.0 2.0 2 0 0 2 2 2 1 Probable RNA and SrmB- binding site of polymerase A DUF4404 PF14357.1 CBZ52553.1 - 0.0086 16.4 1.5 2.6 8.5 0.0 3.7 4 0 0 4 4 4 1 Domain of unknown function (DUF4404) Laminin_I PF06008.9 CBZ52553.1 - 0.069 12.4 0.4 0.12 11.6 0.3 1.5 1 0 0 1 1 1 0 Laminin Domain I Mitofilin PF09731.4 CBZ52554.1 - 0.79 8.3 17.8 1.1 7.7 12.3 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein WD40 PF00400.27 CBZ52555.1 - 0.00064 19.5 7.4 2.1 8.3 0.0 5.3 6 0 0 6 6 6 3 WD domain, G-beta repeat PQQ_3 PF13570.1 CBZ52555.1 - 0.12 12.7 5.6 0.16 12.2 0.1 3.6 4 0 0 4 4 4 0 PQQ-like domain SNO PF01174.14 CBZ52556.1 - 2.3e-42 144.7 0.0 5.2e-25 88.1 0.0 2.0 2 0 0 2 2 2 2 SNO glutamine amidotransferase family GATase_3 PF07685.9 CBZ52556.1 - 1.2e-05 24.9 0.0 1.9e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain DJ-1_PfpI PF01965.19 CBZ52556.1 - 2.9e-05 23.5 0.0 0.00043 19.7 0.0 2.2 2 0 0 2 2 2 1 DJ-1/PfpI family DUF4066 PF13278.1 CBZ52556.1 - 0.0015 17.8 0.1 0.004 16.4 0.0 1.7 2 0 0 2 2 2 1 Putative amidotransferase GATase_5 PF13507.1 CBZ52556.1 - 0.026 13.4 0.0 0.043 12.7 0.0 1.4 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain Peptidase_C26 PF07722.8 CBZ52556.1 - 0.069 12.5 0.0 0.23 10.8 0.0 1.8 1 1 0 1 1 1 0 Peptidase C26 GATase PF00117.23 CBZ52556.1 - 0.085 12.2 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Glutamine amidotransferase class-I Aminotran_4 PF01063.14 CBZ52557.1 - 1.5e-12 47.5 0.0 1.5e-12 47.5 0.0 2.6 3 0 0 3 3 3 1 Aminotransferase class IV Ornatin PF02088.10 CBZ52558.1 - 0.097 12.2 0.1 0.11 12.1 0.1 1.1 1 0 0 1 1 1 0 Ornatin RNase_HII PF01351.13 CBZ52559.1 - 2.2e-12 47.0 3.4 1.4e-07 31.3 0.2 3.1 2 1 1 3 3 3 2 Ribonuclease HII Herpes_PAP PF03325.8 CBZ52559.1 - 0.0098 15.4 2.4 0.14 11.7 0.0 2.1 2 0 0 2 2 2 1 Herpesvirus polymerase accessory protein DUF1444 PF07285.6 CBZ52559.1 - 0.04 13.2 0.1 0.061 12.6 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1444) DUF1510 PF07423.6 CBZ52559.1 - 0.084 12.2 8.6 0.15 11.4 6.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) RNA_polI_A34 PF08208.6 CBZ52559.1 - 0.12 12.0 14.5 0.18 11.4 10.0 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Nop14 PF04147.7 CBZ52559.1 - 0.28 9.0 7.4 0.078 10.8 3.2 1.6 2 0 0 2 2 2 0 Nop14-like family RNase_H2-Ydr279 PF09468.5 CBZ52559.1 - 1.9 7.5 8.6 2.7 7.0 5.9 1.2 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) RR_TM4-6 PF06459.7 CBZ52559.1 - 2.2 8.1 9.1 3.5 7.4 6.3 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 MSA-2c PF12238.3 CBZ52559.1 - 5.7 6.5 9.5 9.3 5.8 6.6 1.3 1 0 0 1 1 1 0 Merozoite surface antigen 2c TSGP1 PF07771.6 CBZ52559.1 - 7.3 6.5 9.0 15 5.4 6.2 1.6 1 0 0 1 1 1 0 Tick salivary peptide group 1 zf-RING_2 PF13639.1 CBZ52560.1 - 2.5e-13 49.6 6.4 2.5e-13 49.6 4.5 1.8 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 CBZ52560.1 - 2.3e-08 33.5 4.0 2.3e-08 33.5 2.8 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CBZ52560.1 - 3.3e-08 33.4 5.7 3.3e-08 33.4 4.0 2.0 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 CBZ52560.1 - 9.1e-08 32.1 3.9 2.7e-07 30.5 2.7 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 CBZ52560.1 - 3.9e-07 29.7 3.2 8.8e-07 28.5 2.2 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 CBZ52560.1 - 7.8e-06 25.6 1.3 7.8e-06 25.6 0.9 1.9 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.3 CBZ52560.1 - 4.2e-05 23.4 5.2 0.00021 21.1 3.6 2.1 1 1 0 1 1 1 1 FANCL C-terminal domain RINGv PF12906.2 CBZ52560.1 - 5.9e-05 23.0 4.9 0.00012 21.9 3.4 1.6 1 0 0 1 1 1 1 RING-variant domain zf-RING_4 PF14570.1 CBZ52560.1 - 0.00046 19.7 5.5 0.0012 18.4 3.8 1.7 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4 PF00097.20 CBZ52560.1 - 0.00051 19.6 5.8 0.00051 19.6 4.0 2.1 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) Baculo_RING PF05883.6 CBZ52560.1 - 0.06 13.1 0.7 0.11 12.2 0.5 1.4 1 0 0 1 1 1 0 Baculovirus U-box/Ring-like domain Rad50_zn_hook PF04423.9 CBZ52560.1 - 0.07 12.6 0.3 2.6 7.5 0.0 2.7 3 0 0 3 3 3 0 Rad50 zinc hook motif zf-P11 PF03854.9 CBZ52560.1 - 0.16 11.4 5.3 0.082 12.3 0.5 2.3 1 1 1 2 2 2 0 P-11 zinc finger Gcd10p PF04189.8 CBZ52561.1 - 8.5e-47 159.7 0.0 1.3e-46 159.1 0.0 1.2 1 0 0 1 1 1 1 Gcd10p family Clathrin_bdg PF15045.1 CBZ52562.1 - 0.073 12.5 0.0 0.19 11.2 0.0 1.6 1 0 0 1 1 1 0 Clathrin-binding box of Aftiphilin, vesicle trafficking VPS9 PF02204.13 CBZ52563.1 - 3e-05 23.9 0.0 6.2e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain PP2C PF00481.16 CBZ52564.1 - 8.7e-38 130.1 0.0 2.7e-37 128.5 0.0 1.7 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 CBZ52564.1 - 1.9e-05 24.2 0.1 4.7e-05 22.8 0.0 1.7 1 1 0 1 1 1 1 Protein phosphatase 2C GRP PF07172.6 CBZ52565.1 - 6.7e-05 23.2 2.6 8.6e-05 22.9 1.8 1.2 1 0 0 1 1 1 1 Glycine rich protein family Aldo_ket_red PF00248.16 CBZ52566.1 - 5.6e-31 107.4 0.0 1.3e-21 76.6 0.0 2.1 1 1 1 2 2 2 2 Aldo/keto reductase family Lactamase_B PF00753.22 CBZ52567.1 - 3.5e-20 72.4 0.4 4.8e-20 72.0 0.3 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 CBZ52567.1 - 0.0087 15.6 0.1 0.015 14.8 0.1 1.7 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Nbl1_Borealin_N PF10444.4 CBZ52569.1 - 0.11 11.8 0.0 0.21 10.9 0.0 1.5 1 0 0 1 1 1 0 Nbl1 / Borealin N terminal Pkinase PF00069.20 CBZ52570.1 - 6.8e-21 74.5 0.0 1.5e-20 73.4 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.1 CBZ52570.1 - 3.1e-16 59.1 0.0 6.4e-16 58.1 0.0 1.5 2 0 0 2 2 2 1 Kinase-like Pkinase_Tyr PF07714.12 CBZ52570.1 - 2.4e-06 26.8 0.0 3.9e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 CBZ52570.1 - 3.5e-05 22.9 0.0 6.8e-05 22.0 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family HMG_box PF00505.14 CBZ52571.1 - 1.4e-09 38.1 0.9 9e-09 35.4 0.7 3.1 3 0 0 3 3 3 2 HMG (high mobility group) box HMG_box_2 PF09011.5 CBZ52571.1 - 0.0026 18.0 1.2 0.0026 18.0 0.8 3.6 4 0 0 4 4 4 1 HMG-box domain SET PF00856.23 CBZ52571.1 - 0.0053 17.0 0.0 0.0053 17.0 0.0 4.3 2 1 1 3 3 3 1 SET domain ATP-synt_D PF01813.12 CBZ52573.1 - 8.7e-60 201.6 0.4 1e-59 201.4 0.3 1.0 1 0 0 1 1 1 1 ATP synthase subunit D CorA PF01544.13 CBZ52573.1 - 0.061 12.3 0.1 0.094 11.7 0.0 1.3 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein SAG PF04092.8 CBZ52574.1 - 3.8e-15 56.3 13.7 2.7e-07 30.9 5.0 2.2 2 0 0 2 2 2 2 SRS domain DER1 PF04511.10 CBZ52575.1 - 2.5e-20 72.8 0.0 3.8e-20 72.2 0.0 1.2 1 0 0 1 1 1 1 Der1-like family TFIIF_beta PF02270.10 CBZ52575.1 - 1.2e-06 28.5 0.0 0.00082 19.2 0.0 3.0 2 1 0 2 2 2 2 Transcription initiation factor IIF, beta subunit ADK PF00406.17 CBZ52577.1 - 1.3e-28 99.8 0.0 2.1e-28 99.1 0.0 1.3 1 0 0 1 1 1 1 Adenylate kinase AAA_18 PF13238.1 CBZ52577.1 - 4.2e-14 52.9 0.4 2e-13 50.7 0.0 2.0 1 1 0 2 2 2 1 AAA domain AAA_17 PF13207.1 CBZ52577.1 - 3.6e-11 43.9 0.2 7.7e-11 42.8 0.1 1.6 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 CBZ52577.1 - 2.4e-08 33.9 0.1 1.8e-07 31.1 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.1 CBZ52577.1 - 0.0017 18.3 0.0 0.0034 17.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.5 CBZ52577.1 - 0.003 16.8 0.1 0.0048 16.1 0.0 1.3 1 0 0 1 1 1 1 Chromatin associated protein KTI12 Cytidylate_kin2 PF13189.1 CBZ52577.1 - 0.044 13.6 0.2 0.15 11.9 0.1 2.0 1 1 0 1 1 1 0 Cytidylate kinase-like family CTP_transf_1 PF01148.15 CBZ52578.1 - 3e-65 220.4 11.0 2.5e-64 217.4 7.6 2.2 1 1 0 1 1 1 1 Cytidylyltransferase family Isochorismatase PF00857.15 CBZ52579.1 - 2.7e-20 73.0 0.0 9.3e-16 58.2 0.0 2.3 2 0 0 2 2 2 2 Isochorismatase family PP2C PF00481.16 CBZ52583.1 - 1.2e-13 51.0 0.0 3.3e-09 36.5 0.0 2.3 2 0 0 2 2 2 2 Protein phosphatase 2C Cofilin_ADF PF00241.15 CBZ52585.1 - 0.047 13.5 0.0 0.096 12.5 0.0 1.5 1 0 0 1 1 1 0 Cofilin/tropomyosin-type actin-binding protein COX4 PF02936.9 CBZ52588.1 - 1.1 8.9 3.0 18 5.0 0.3 2.3 1 1 0 2 2 2 0 Cytochrome c oxidase subunit IV DUF4391 PF14335.1 CBZ52590.1 - 0.09 12.1 0.2 0.13 11.6 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4391) NUDIX PF00293.23 CBZ52591.1 - 7.9e-14 51.4 0.4 3.4e-13 49.3 0.2 2.1 1 1 0 1 1 1 1 NUDIX domain AAA_2 PF07724.9 CBZ52592.1 - 1.9e-42 145.0 1.3 4e-40 137.5 0.1 3.5 2 2 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA PF00004.24 CBZ52592.1 - 2.9e-25 88.9 0.1 4.4e-12 46.3 0.0 2.9 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.4 CBZ52592.1 - 1.2e-17 63.5 0.1 3e-16 59.0 0.0 3.1 3 0 0 3 3 2 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.9 CBZ52592.1 - 5.5e-16 58.5 0.4 7.5e-10 38.6 0.0 3.3 3 1 0 3 3 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 CBZ52592.1 - 1.5e-13 51.1 2.5 6.4e-05 23.0 0.0 4.7 3 1 0 4 4 4 2 AAA ATPase domain AAA_22 PF13401.1 CBZ52592.1 - 1.5e-12 47.7 0.9 0.00052 20.1 0.0 4.5 3 1 0 3 3 3 2 AAA domain Clp_N PF02861.15 CBZ52592.1 - 1.6e-08 34.3 0.0 0.0082 16.0 0.0 3.0 2 0 0 2 2 2 2 Clp amino terminal domain IstB_IS21 PF01695.12 CBZ52592.1 - 7.2e-08 32.0 0.0 0.0091 15.4 0.0 2.6 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_14 PF13173.1 CBZ52592.1 - 1.8e-07 31.1 0.1 0.057 13.3 0.0 3.6 4 0 0 4 4 4 2 AAA domain Sigma54_activat PF00158.21 CBZ52592.1 - 2.2e-07 30.4 1.5 1.3e-05 24.7 0.0 3.1 2 1 0 2 2 2 1 Sigma-54 interaction domain AAA_17 PF13207.1 CBZ52592.1 - 9.6e-07 29.6 4.5 0.0068 17.2 0.0 3.8 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.1 CBZ52592.1 - 6.4e-06 26.4 4.8 0.043 14.1 0.0 4.1 3 1 1 4 4 3 2 AAA domain RuvB_N PF05496.7 CBZ52592.1 - 9.6e-06 24.8 0.6 0.0095 15.0 0.0 4.0 5 0 0 5 5 4 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 CBZ52592.1 - 2.4e-05 24.0 0.0 0.079 12.7 0.0 3.1 2 0 0 2 2 2 2 Part of AAA domain TniB PF05621.6 CBZ52592.1 - 3.1e-05 22.9 0.0 0.00013 20.8 0.0 1.9 2 0 0 2 2 2 1 Bacterial TniB protein RNA_helicase PF00910.17 CBZ52592.1 - 3.8e-05 23.8 0.0 0.26 11.4 0.0 2.9 2 1 0 2 2 2 2 RNA helicase NACHT PF05729.7 CBZ52592.1 - 5.1e-05 22.9 0.0 0.16 11.6 0.0 3.1 2 0 0 2 2 2 2 NACHT domain Zeta_toxin PF06414.7 CBZ52592.1 - 8.4e-05 21.7 0.7 0.0029 16.7 0.0 3.0 3 0 0 3 3 3 1 Zeta toxin AAA_33 PF13671.1 CBZ52592.1 - 8.8e-05 22.4 0.0 0.041 13.7 0.0 3.1 3 0 0 3 3 2 1 AAA domain Arch_ATPase PF01637.13 CBZ52592.1 - 0.00013 21.7 8.2 0.69 9.5 0.1 5.1 3 2 0 3 3 3 1 Archaeal ATPase AAA_25 PF13481.1 CBZ52592.1 - 0.00017 21.0 0.1 0.18 11.2 0.0 3.0 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.16 CBZ52592.1 - 0.00024 20.3 1.8 0.66 9.1 0.3 3.4 3 1 0 3 3 3 2 Magnesium chelatase, subunit ChlI ResIII PF04851.10 CBZ52592.1 - 0.0011 18.8 3.1 2 8.2 0.0 4.3 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit AAA_28 PF13521.1 CBZ52592.1 - 0.0016 18.4 3.1 1.2 9.0 0.0 3.8 3 1 1 4 4 4 1 AAA domain T2SE PF00437.15 CBZ52592.1 - 0.003 16.5 0.0 0.0088 14.9 0.0 1.8 2 0 0 2 2 1 1 Type II/IV secretion system protein AAA_10 PF12846.2 CBZ52592.1 - 0.0044 16.5 0.2 1.3 8.3 0.0 3.4 3 1 0 3 3 3 1 AAA-like domain DUF258 PF03193.11 CBZ52592.1 - 0.0076 15.4 0.0 2.3 7.4 0.0 2.6 2 0 0 2 2 2 1 Protein of unknown function, DUF258 ABC_tran PF00005.22 CBZ52592.1 - 0.017 15.4 3.7 0.25 11.6 0.0 3.6 3 1 0 3 3 3 0 ABC transporter AAA_3 PF07726.6 CBZ52592.1 - 0.018 14.6 0.1 15 5.1 0.0 3.5 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.1 CBZ52592.1 - 0.024 14.3 0.0 0.41 10.3 0.0 2.7 1 1 0 1 1 1 0 DNA polymerase III, delta subunit MMR_HSR1 PF01926.18 CBZ52592.1 - 0.03 14.2 0.0 11 6.0 0.0 3.2 2 0 0 2 2 2 0 50S ribosome-binding GTPase UPF0079 PF02367.12 CBZ52592.1 - 0.033 13.8 0.2 6.4 6.4 0.0 2.6 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 GYF PF02213.11 CBZ52592.1 - 0.27 10.8 0.0 0.61 9.7 0.0 1.5 1 0 0 1 1 1 0 GYF domain Miro PF08477.8 CBZ52592.1 - 1.4 9.4 5.0 18 5.8 0.0 3.9 5 0 0 5 5 3 0 Miro-like protein AP2 PF00847.15 CBZ52593.1 - 6.4e-06 26.2 4.9 1.2e-05 25.3 3.4 1.5 1 0 0 1 1 1 1 AP2 domain AP2 PF00847.15 CBZ52594.1 - 1.3e-26 92.4 7.3 1.9e-09 37.4 1.3 3.5 3 0 0 3 3 3 3 AP2 domain DUF4110 PF13422.1 CBZ52594.1 - 2.2 8.1 5.8 2 8.3 0.5 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4110) ATP-sulfurylase PF01747.12 CBZ52595.1 - 3.1e-75 252.1 0.0 4.1e-75 251.7 0.0 1.1 1 0 0 1 1 1 1 ATP-sulfurylase APS_kinase PF01583.15 CBZ52595.1 - 2.4e-57 192.9 0.0 4.7e-57 192.0 0.0 1.5 1 0 0 1 1 1 1 Adenylylsulphate kinase PUA_2 PF14306.1 CBZ52595.1 - 1.2e-28 99.5 0.0 1.1e-26 93.1 0.0 2.3 1 1 0 1 1 1 1 PUA-like domain AAA_33 PF13671.1 CBZ52595.1 - 7.4e-09 35.6 0.0 1.1e-08 35.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.5 CBZ52595.1 - 3.1e-05 23.3 0.0 5.7e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_17 PF13207.1 CBZ52595.1 - 4e-05 24.4 0.0 0.00011 22.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 CBZ52595.1 - 0.00011 22.5 0.0 0.00025 21.3 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.1 CBZ52595.1 - 0.0022 18.0 0.0 0.0044 16.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.1 CBZ52595.1 - 0.051 13.1 0.0 0.21 11.1 0.0 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_16 PF13191.1 CBZ52595.1 - 0.12 12.4 0.0 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Zeta_toxin PF06414.7 CBZ52595.1 - 0.14 11.2 0.0 0.31 10.1 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin ArgK PF03308.11 CBZ52595.1 - 0.16 10.7 0.0 0.25 10.0 0.0 1.2 1 0 0 1 1 1 0 ArgK protein Mg_chelatase PF01078.16 CBZ52595.1 - 0.17 10.9 0.0 0.31 10.1 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI RPN7 PF10602.4 CBZ52596.1 - 0.00024 20.5 0.0 0.0022 17.4 0.0 2.2 1 1 1 2 2 2 1 26S proteasome subunit RPN7 PCI PF01399.22 CBZ52596.1 - 0.094 13.0 0.0 0.22 11.8 0.0 1.6 1 0 0 1 1 1 0 PCI domain Laminin_II PF06009.7 CBZ52597.1 - 0.0066 16.2 2.7 0.0066 16.2 1.9 1.7 2 0 0 2 2 2 1 Laminin Domain II DBINO PF13892.1 CBZ52597.1 - 0.15 12.1 12.1 0.2 11.6 8.2 1.3 1 1 0 1 1 1 0 DNA-binding domain HAUS-augmin3 PF14932.1 CBZ52597.1 - 0.16 11.1 12.9 0.24 10.5 8.9 1.4 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 DUF2951 PF11166.3 CBZ52597.1 - 0.57 10.0 8.2 0.45 10.3 4.4 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2951) DUF342 PF03961.8 CBZ52597.1 - 1.4 7.2 9.5 1.6 7.0 6.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Exonuc_VII_L PF02601.10 CBZ52597.1 - 1.6 7.8 13.2 2 7.5 9.2 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF972 PF06156.8 CBZ52597.1 - 5.3 7.4 14.2 0.25 11.6 1.5 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF972) TMPIT PF07851.8 CBZ52597.1 - 5.5 5.9 12.4 1.2 8.0 6.5 1.4 2 0 0 2 2 2 0 TMPIT-like protein DivIC PF04977.10 CBZ52597.1 - 7.2 6.1 11.3 0.97 8.9 1.0 3.3 2 2 0 2 2 2 0 Septum formation initiator IncA PF04156.9 CBZ52597.1 - 7.9 6.0 14.6 30 4.1 10.1 1.8 1 1 0 1 1 1 0 IncA protein HEM4 PF02602.10 CBZ52599.1 - 0.00032 20.0 1.2 0.0077 15.5 0.1 3.4 5 0 0 5 5 5 1 Uroporphyrinogen-III synthase HemD TruD PF01142.13 CBZ52600.1 - 2.1e-37 128.6 0.0 5.8e-14 51.5 0.0 5.3 5 0 0 5 5 5 4 tRNA pseudouridine synthase D (TruD) APG6 PF04111.7 CBZ52601.1 - 0.0024 16.9 16.7 0.0024 16.9 11.6 5.8 3 1 1 6 6 6 3 Autophagy protein Apg6 NYD-SP28_assoc PF14775.1 CBZ52601.1 - 0.068 12.8 16.4 0.21 11.3 0.4 4.2 4 0 0 4 4 4 0 Sperm tail C-terminal domain DEAD PF00270.24 CBZ52603.1 - 2.2e-30 105.3 0.0 4.2e-30 104.4 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CBZ52603.1 - 7.1e-23 80.2 0.0 1.7e-22 79.0 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 CBZ52603.1 - 1.1e-05 25.3 0.0 2.1e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.1 CBZ52603.1 - 0.00093 18.8 2.6 0.0027 17.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 CBZ52603.1 - 0.002 17.8 0.0 0.012 15.3 0.0 2.3 1 0 0 1 1 1 1 Part of AAA domain SNF2_N PF00176.18 CBZ52603.1 - 0.0023 16.7 0.2 0.0066 15.2 0.0 1.7 2 0 0 2 2 2 1 SNF2 family N-terminal domain AAA_22 PF13401.1 CBZ52603.1 - 0.0029 17.7 1.3 0.0096 16.0 0.1 2.5 2 1 0 2 2 2 1 AAA domain AAA PF00004.24 CBZ52603.1 - 0.15 12.2 1.6 1.4 9.1 0.0 2.8 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) TetR_N PF00440.18 CBZ52603.1 - 2.7 7.6 5.2 0.35 10.5 0.1 2.2 2 0 0 2 2 2 0 Bacterial regulatory proteins, tetR family Mgm101p PF06420.7 CBZ52605.1 - 0.17 11.2 0.1 0.31 10.3 0.1 1.3 1 0 0 1 1 1 0 Mitochondrial genome maintenance MGM101 Bud13 PF09736.4 CBZ52606.1 - 1.2e-40 139.1 7.1 3.5e-40 137.6 4.9 1.8 1 0 0 1 1 1 1 Pre-mRNA-splicing factor of RES complex DUF905 PF06006.7 CBZ52606.1 - 0.07 12.5 0.7 0.16 11.3 0.5 1.5 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF905) Myb_DNA-binding PF00249.26 CBZ52607.1 - 1.8e-22 79.1 0.9 8.6e-08 32.1 0.0 3.7 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 CBZ52607.1 - 1.4e-18 66.7 0.0 1e-06 28.7 0.0 3.6 1 1 2 3 3 3 3 Myb-like DNA-binding domain Adeno_terminal PF02459.10 CBZ52607.1 - 0.092 10.9 2.1 0.16 10.1 1.4 1.3 1 0 0 1 1 1 0 Adenoviral DNA terminal protein Fmp27 PF10344.4 CBZ52607.1 - 1.6 6.2 0.4 2.3 5.7 0.3 1.1 1 0 0 1 1 1 0 Mitochondrial protein from FMP27 RF-1 PF00472.15 CBZ52608.1 - 0.0026 17.5 2.5 0.0033 17.2 1.7 1.2 1 0 0 1 1 1 1 RF-1 domain GTPase_Cys_C PF12631.2 CBZ52608.1 - 0.063 13.6 0.1 0.072 13.5 0.1 1.3 1 1 0 1 1 1 0 Catalytic cysteine-containing C-terminus of GTPase, MnmE WGR PF05406.10 CBZ52608.1 - 0.075 12.9 1.0 0.34 10.9 0.2 1.9 2 0 0 2 2 2 0 WGR domain MRP-S28 PF10213.4 CBZ52608.1 - 0.094 12.8 0.4 0.12 12.4 0.3 1.3 1 1 0 1 1 1 0 Mitochondrial ribosomal subunit protein Exonuc_VII_L PF02601.10 CBZ52608.1 - 0.32 10.1 2.8 0.34 10.0 1.9 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit Gryzun PF07919.7 CBZ52609.1 - 2.7e-07 29.2 0.0 3.9e-07 28.7 0.0 1.1 1 0 0 1 1 1 1 Gryzun, putative trafficking through Golgi Foie-gras_1 PF11817.3 CBZ52609.1 - 0.00019 21.0 0.2 0.0032 16.9 0.1 2.6 1 1 0 1 1 1 1 Foie gras liver health family 1 Baculo_ME53 PF06061.6 CBZ52609.1 - 6.2 5.7 0.0 9.6 5.0 0.0 1.2 1 0 0 1 1 1 0 Baculoviridae ME53 PP-binding PF00550.20 CBZ52610.1 - 3e-12 46.5 0.3 4.2e-12 46.1 0.2 1.2 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.1 CBZ52610.1 - 0.00021 21.2 0.1 0.00037 20.4 0.1 1.3 1 0 0 1 1 1 1 Acyl-carrier Ribosomal_L50 PF10501.4 CBZ52610.1 - 0.00035 20.5 0.0 0.00046 20.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal subunit 39S DUF1493 PF07377.7 CBZ52610.1 - 0.0036 17.3 0.0 0.0052 16.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1493) F5_F8_type_C PF00754.20 CBZ52611.1 - 1.2e-15 57.4 0.4 3.7e-14 52.6 0.0 2.5 2 0 0 2 2 2 1 F5/8 type C domain LCCL PF03815.14 CBZ52611.1 - 1.8e-06 27.8 0.0 4.2e-06 26.6 0.0 1.6 1 0 0 1 1 1 1 LCCL domain DUF1080 PF06439.6 CBZ52611.1 - 0.0013 18.6 0.0 0.0026 17.6 0.0 1.5 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1080) PCI PF01399.22 CBZ52612.1 - 5.2e-05 23.5 0.0 0.00019 21.7 0.0 1.9 1 0 0 1 1 1 1 PCI domain TPR_7 PF13176.1 CBZ52612.1 - 0.018 14.8 0.0 3.3 7.7 0.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.23 CBZ52612.1 - 0.023 14.2 0.3 0.093 12.3 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 CBZ52612.1 - 0.027 15.0 0.0 0.13 12.9 0.0 2.2 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_8 PF13181.1 CBZ52612.1 - 0.032 13.9 0.1 0.24 11.2 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.12 CBZ52612.1 - 0.035 14.0 0.2 0.18 11.7 0.1 2.3 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_19 PF14559.1 CBZ52612.1 - 0.1 12.9 0.2 0.32 11.3 0.1 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat UQ_con PF00179.21 CBZ52613.1 - 1.9e-18 66.2 0.0 2.7e-18 65.7 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UFC1 PF08694.6 CBZ52613.1 - 0.0098 15.3 0.0 0.016 14.7 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-fold modifier-conjugating enzyme 1 Aminotran_1_2 PF00155.16 CBZ52615.1 - 4.6e-42 144.2 0.0 6.6e-42 143.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 CBZ52615.1 - 0.092 11.8 0.0 0.15 11.1 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase Bromodomain PF00439.20 CBZ52616.1 - 1.1e-05 25.2 0.0 1.7e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Bromodomain DUF1777 PF08648.7 CBZ52617.1 - 3.1e-22 79.1 18.3 3.1e-22 79.1 12.7 2.9 1 1 2 3 3 3 1 Protein of unknown function (DUF1777) Aldedh PF00171.17 CBZ52618.1 - 4.6e-08 31.8 1.8 0.018 13.3 0.0 3.1 3 0 0 3 3 3 3 Aldehyde dehydrogenase family DUF2292 PF10055.4 CBZ52618.1 - 0.14 11.5 0.0 0.42 9.9 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized small protein (DUF2292) Unstab_antitox PF09720.5 CBZ52618.1 - 0.18 11.5 0.7 0.32 10.7 0.5 1.4 1 0 0 1 1 1 0 Putative addiction module component PPR_2 PF13041.1 CBZ52620.1 - 4.2e-43 145.0 0.0 2.7e-12 46.4 0.0 8.9 6 2 4 10 10 10 6 PPR repeat family PPR_3 PF13812.1 CBZ52620.1 - 1.7e-27 93.3 16.5 0.003 17.7 0.0 10.8 11 0 0 11 11 11 7 Pentatricopeptide repeat domain PPR_1 PF12854.2 CBZ52620.1 - 8.7e-24 82.7 0.6 0.00019 20.8 0.0 8.7 8 0 0 8 8 8 6 PPR repeat PPR PF01535.15 CBZ52620.1 - 6.6e-23 79.0 10.4 0.002 18.0 0.0 11.2 12 0 0 12 12 12 5 PPR repeat tRNA-synt_1c PF00749.16 CBZ52621.1 - 1.3e-101 339.4 0.0 1.7e-101 339.0 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 CBZ52621.1 - 1.7e-35 122.2 0.0 1.4e-34 119.3 0.0 2.2 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), anti-codon binding domain GST_C_3 PF14497.1 CBZ52621.1 - 6.2e-07 29.8 0.1 3.5e-06 27.4 0.0 2.3 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 CBZ52621.1 - 2e-05 24.4 0.2 0.00018 21.4 0.0 2.4 2 1 1 3 3 3 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 CBZ52621.1 - 0.00015 21.5 0.1 0.00056 19.7 0.1 2.0 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Hep_59 PF07052.6 CBZ52622.1 - 1.1e-19 70.7 0.1 1.1e-19 70.7 0.0 3.1 2 1 0 3 3 3 1 Hepatocellular carcinoma-associated antigen 59 TMEM247 PF15444.1 CBZ52622.1 - 0.018 14.9 5.6 1.9 8.2 0.0 2.3 1 1 1 2 2 2 0 Transmembrane protein 247 PGA2 PF07543.7 CBZ52622.1 - 3.2 7.5 10.8 0.11 12.2 2.3 2.3 2 0 0 2 2 2 0 Protein trafficking PGA2 TPR_20 PF14561.1 CBZ52624.1 - 0.053 13.6 2.6 3.5 7.8 0.0 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat FliJ PF02050.11 CBZ52624.1 - 0.063 13.3 0.8 0.16 12.0 0.5 1.7 1 0 0 1 1 1 0 Flagellar FliJ protein DEAD PF00270.24 CBZ52625.1 - 4.5e-37 127.1 0.0 1.2e-36 125.7 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CBZ52625.1 - 2.3e-26 91.4 0.1 7.2e-26 89.8 0.1 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 CBZ52625.1 - 0.22 11.3 0.0 0.22 11.3 0.0 3.3 4 0 0 4 4 4 0 Type III restriction enzyme, res subunit CENP-T PF15511.1 CBZ52626.1 - 1.9 7.6 11.5 2.4 7.2 8.0 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T RNase_P_p30 PF01876.11 CBZ52627.1 - 4.9e-16 58.2 0.2 4.5e-07 29.2 0.0 2.8 3 0 0 3 3 3 2 RNase P subunit p30 CTP_transf_1 PF01148.15 CBZ52628.1 - 9e-23 81.2 1.3 1.5e-22 80.5 0.9 1.3 1 0 0 1 1 1 1 Cytidylyltransferase family DUF2217 PF10265.4 CBZ52629.1 - 0.22 10.2 1.3 0.32 9.7 0.9 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) CENP-T PF15511.1 CBZ52632.1 - 0.38 9.9 21.6 0.44 9.7 15.0 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Nop14 PF04147.7 CBZ52632.1 - 1 7.2 29.6 1.2 6.9 20.5 1.1 1 0 0 1 1 1 0 Nop14-like family Daxx PF03344.10 CBZ52632.1 - 1.4 7.3 32.4 1.3 7.3 22.5 1.0 1 0 0 1 1 1 0 Daxx Family DUF3530 PF12048.3 CBZ52632.1 - 2.2 7.1 4.2 2.3 7.0 2.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) BSP_II PF05432.6 CBZ52632.1 - 2.7 7.1 33.8 3.5 6.8 23.4 1.3 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) DUF2722 PF10846.3 CBZ52632.1 - 3.5 6.5 8.1 3.7 6.4 5.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) SpoIIIAH PF12685.2 CBZ52632.1 - 5.1 6.5 11.0 7 6.0 7.6 1.2 1 0 0 1 1 1 0 SpoIIIAH-like protein ABC_tran PF00005.22 CBZ52633.1 - 1.4e-25 90.2 0.0 3.7e-24 85.5 0.0 2.4 2 0 0 2 2 2 1 ABC transporter ABC_membrane PF00664.18 CBZ52633.1 - 7.3e-11 41.9 0.8 1e-10 41.5 0.5 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region AAA_21 PF13304.1 CBZ52633.1 - 9.1e-05 22.5 0.1 0.31 10.9 0.0 2.1 2 0 0 2 2 2 2 AAA domain SbcCD_C PF13558.1 CBZ52633.1 - 0.0012 18.6 0.0 0.0049 16.7 0.0 2.1 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_25 PF13481.1 CBZ52633.1 - 0.0026 17.1 0.0 0.0055 16.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 CBZ52633.1 - 0.0032 17.4 0.5 0.0032 17.4 0.3 1.8 2 0 0 2 2 2 1 AAA ATPase domain AAA_17 PF13207.1 CBZ52633.1 - 0.004 17.9 0.0 0.0077 17.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain SMC_N PF02463.14 CBZ52633.1 - 0.006 15.8 0.0 1.2 8.3 0.0 2.4 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.1 CBZ52633.1 - 0.016 15.3 0.0 0.16 12.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain DUF3987 PF13148.1 CBZ52633.1 - 0.02 13.4 0.0 0.038 12.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) AAA_18 PF13238.1 CBZ52633.1 - 0.023 14.9 0.0 0.041 14.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 CBZ52633.1 - 0.035 13.6 0.2 0.11 12.0 0.0 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_10 PF12846.2 CBZ52633.1 - 0.067 12.6 0.1 0.81 9.0 0.1 2.1 2 0 0 2 2 2 0 AAA-like domain DUF87 PF01935.12 CBZ52633.1 - 0.074 12.8 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function DUF87 PI31_Prot_C PF08577.6 CBZ52633.1 - 0.13 12.8 0.5 0.27 11.8 0.3 1.5 1 0 0 1 1 1 0 PI31 proteasome regulator AAA_5 PF07728.9 CBZ52633.1 - 0.14 11.8 0.1 0.59 9.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) DAO PF01266.19 CBZ52634.1 - 7e-34 117.2 0.1 9.2e-34 116.9 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.2 CBZ52634.1 - 6.1e-06 25.5 1.0 1.2e-05 24.6 0.7 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 CBZ52634.1 - 1.3e-05 24.2 0.2 2e-05 23.6 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 CBZ52634.1 - 0.0051 16.7 0.0 0.0092 15.8 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 CBZ52634.1 - 0.027 14.5 1.7 0.13 12.3 1.0 2.1 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 CBZ52634.1 - 0.056 12.4 0.5 0.1 11.6 0.4 1.4 1 0 0 1 1 1 0 FAD binding domain Thi4 PF01946.12 CBZ52634.1 - 0.081 12.0 0.1 0.14 11.1 0.1 1.3 1 0 0 1 1 1 0 Thi4 family GIDA PF01134.17 CBZ52634.1 - 0.084 11.7 0.5 0.12 11.1 0.4 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A HI0933_like PF03486.9 CBZ52634.1 - 0.11 10.9 0.5 0.17 10.3 0.3 1.3 1 0 0 1 1 1 0 HI0933-like protein HMG_box PF00505.14 CBZ52635.1 - 1.7e-21 76.2 2.0 2.6e-21 75.6 1.4 1.3 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 CBZ52635.1 - 2.9e-14 53.1 2.3 4.8e-14 52.4 1.6 1.4 1 0 0 1 1 1 1 HMG-box domain HMG_box_5 PF14887.1 CBZ52635.1 - 0.051 13.3 2.0 0.054 13.2 0.7 1.7 1 1 0 1 1 1 0 HMG (high mobility group) box 5 Globin PF00042.17 CBZ52635.1 - 0.09 13.1 0.1 0.11 12.8 0.0 1.1 1 0 0 1 1 1 0 Globin Ribosomal_S11 PF00411.14 CBZ52637.1 - 2.6e-42 143.4 0.5 3.6e-42 142.9 0.4 1.2 1 0 0 1 1 1 1 Ribosomal protein S11 DUF2252 PF10009.4 CBZ52637.1 - 0.07 12.0 0.0 0.07 12.0 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2252) DUF814 PF05670.8 CBZ52637.1 - 0.1 12.4 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF814) DIE2_ALG10 PF04922.7 CBZ52638.1 - 2.7e-35 122.1 0.0 3.5e-21 75.6 0.0 2.5 2 1 0 2 2 2 2 DIE2/ALG10 family FtsJ PF01728.14 CBZ52640.1 - 1.1e-61 207.9 0.0 2.2e-61 206.9 0.0 1.5 1 1 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_31 PF13847.1 CBZ52640.1 - 0.0064 16.0 0.0 0.013 15.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CBZ52640.1 - 0.018 15.6 0.0 0.053 14.1 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_26 PF13659.1 CBZ52640.1 - 0.026 14.5 0.0 0.049 13.6 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain COPI_assoc PF08507.5 CBZ52641.1 - 0.0023 17.6 1.5 0.0032 17.1 1.0 1.2 1 0 0 1 1 1 1 COPI associated protein Cg6151-P PF10233.4 CBZ52641.1 - 0.029 14.3 1.6 0.053 13.4 1.1 1.4 1 1 0 1 1 1 0 Uncharacterized conserved protein CG6151-P OB_NTP_bind PF07717.11 CBZ52642.1 - 5.7e-29 100.2 0.0 1.6e-28 98.8 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 CBZ52642.1 - 1.8e-27 95.3 1.1 3.5e-27 94.4 0.0 2.2 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.26 CBZ52642.1 - 4e-12 45.8 0.0 9.9e-12 44.5 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 CBZ52642.1 - 5.2e-05 22.7 0.0 0.00014 21.4 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase T2SE PF00437.15 CBZ52642.1 - 0.00027 19.9 0.0 0.00059 18.8 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_22 PF13401.1 CBZ52642.1 - 0.00034 20.7 0.0 0.0018 18.4 0.0 2.3 1 1 0 1 1 1 1 AAA domain Vmethyltransf_C PF08456.5 CBZ52642.1 - 0.017 14.5 3.0 0.035 13.5 1.8 1.7 1 1 0 1 1 1 0 Viral methyltransferase C-terminal AAA_23 PF13476.1 CBZ52642.1 - 3.1 8.0 0.0 3.1 8.0 0.0 3.2 2 1 1 3 3 3 0 AAA domain RRM_1 PF00076.17 CBZ52646.1 - 3.2e-14 52.2 0.0 6.6e-14 51.3 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBZ52646.1 - 5.8e-07 29.4 0.0 1.2e-06 28.4 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBZ52646.1 - 0.001 18.8 0.0 0.0019 18.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF572 PF04502.8 CBZ52646.1 - 0.44 9.7 17.9 0.59 9.3 12.4 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Gluconate_2-dh3 PF13618.1 CBZ52646.1 - 2.2 8.4 5.9 1.8 8.7 2.9 1.8 2 0 0 2 2 2 0 Gluconate 2-dehydrogenase subunit 3 CAF-1_p150 PF11600.3 CBZ52646.1 - 2.2 7.6 28.9 3 7.1 20.0 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF4140 PF13600.1 CBZ52646.1 - 2.4 8.6 13.0 16 6.0 0.0 2.6 3 0 0 3 3 3 0 N-terminal domain of unknown function (DUF4140) TMPIT PF07851.8 CBZ52646.1 - 2.9 6.8 5.0 4 6.4 3.4 1.2 1 0 0 1 1 1 0 TMPIT-like protein Ank_2 PF12796.2 CBZ52648.1 - 5.2e-25 87.5 0.1 9.8e-14 51.4 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 CBZ52648.1 - 4.1e-22 76.8 0.0 3.9e-06 26.4 0.0 4.7 4 0 0 4 4 4 3 Ankyrin repeat Bromodomain PF00439.20 CBZ52648.1 - 5.6e-21 74.2 0.0 3.2e-20 71.8 0.0 2.2 2 0 0 2 2 2 1 Bromodomain Ank_4 PF13637.1 CBZ52648.1 - 1.6e-17 63.5 2.0 8.8e-07 29.2 0.0 4.2 2 1 3 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 CBZ52648.1 - 5.7e-16 57.0 0.0 0.0002 21.3 0.0 4.8 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.1 CBZ52648.1 - 2.5e-14 52.9 0.4 1.1e-06 28.6 0.1 2.7 2 0 0 2 2 2 2 Ankyrin repeats (many copies) DUF3510 PF12022.3 CBZ52648.1 - 0.06 13.4 0.3 0.15 12.1 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3510) MRP-L47 PF06984.8 CBZ52651.1 - 2.3e-27 94.7 1.4 2.3e-27 94.7 1.0 2.4 2 1 1 3 3 3 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) DUF2750 PF11042.3 CBZ52651.1 - 0.012 15.6 0.5 0.027 14.4 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2750) V_ATPase_I PF01496.14 CBZ52651.1 - 0.41 8.4 4.3 0.48 8.2 3.0 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Cpn10 PF00166.16 CBZ52653.1 - 4e-25 87.5 0.1 4.4e-25 87.4 0.1 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit STOP PF05217.7 CBZ52654.1 - 8e-41 140.1 0.2 1.3e-31 110.0 0.0 2.7 2 1 1 3 3 3 2 STOP protein Spc97_Spc98 PF04130.8 CBZ52655.1 - 2.8e-50 171.1 0.0 4.1e-49 167.3 0.0 2.3 2 1 0 2 2 2 1 Spc97 / Spc98 family IR1-M PF12185.3 CBZ52655.1 - 0.26 11.0 0.1 0.87 9.3 0.1 1.9 1 0 0 1 1 1 0 Nup358/RanBP2 E3 ligase domain Lact_bio_phlase PF09508.5 CBZ52655.1 - 1.5 6.4 0.0 2.1 5.9 0.0 1.1 1 0 0 1 1 1 0 Lacto-N-biose phosphorylase Vps26 PF03643.10 CBZ52656.1 - 1.4e-108 361.9 3.1 1.5e-108 361.7 2.1 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 UQ_con PF00179.21 CBZ52657.1 - 2.4e-44 150.1 0.0 2.7e-44 149.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 CBZ52657.1 - 0.0017 18.1 0.0 0.0021 17.8 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 CBZ52657.1 - 0.0093 15.8 0.0 0.012 15.5 0.0 1.2 1 0 0 1 1 1 1 RWD domain Na_H_Exchanger PF00999.16 CBZ52658.1 - 8.6e-48 162.7 33.9 1.1e-47 162.4 23.5 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family GWT1 PF06423.7 CBZ52658.1 - 0.011 15.7 1.3 0.026 14.5 0.9 1.7 1 0 0 1 1 1 0 GWT1 UPF0154 PF03672.8 CBZ52658.1 - 1.5 8.5 3.1 3.1 7.4 0.2 2.7 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0154) Peptidase_C12 PF01088.16 CBZ52659.1 - 1.8e-55 187.4 0.0 2e-52 177.4 0.0 2.1 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase, family 1 La PF05383.12 CBZ52660.1 - 5.7e-07 29.2 0.0 0.015 15.0 0.0 2.3 2 0 0 2 2 2 2 La domain Nop53 PF07767.6 CBZ52661.1 - 1.1e-20 74.0 53.8 6.9e-12 45.0 12.6 3.3 1 1 1 3 3 3 3 Nop53 (60S ribosomal biogenesis) BOP1NT PF08145.7 CBZ52661.1 - 0.0059 16.3 0.1 0.0059 16.3 0.0 3.1 3 0 0 3 3 3 1 BOP1NT (NUC169) domain Pneumo_att_G PF05539.6 CBZ52661.1 - 7.6 5.7 19.1 15 4.8 13.2 1.5 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G NAD_binding_2 PF03446.10 CBZ52662.1 - 1.7e-51 174.2 0.1 2.4e-51 173.8 0.1 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 CBZ52662.1 - 7.8e-34 116.3 1.2 1.3e-33 115.6 0.2 1.7 2 0 0 2 2 2 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.12 CBZ52662.1 - 2e-11 44.1 0.0 6.3e-11 42.5 0.0 1.9 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.15 CBZ52662.1 - 3.1e-08 33.8 0.0 7.4e-08 32.5 0.0 1.6 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.14 CBZ52662.1 - 8.1e-07 28.3 0.0 1.3e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.13 CBZ52662.1 - 0.00019 21.1 0.0 0.0004 20.0 0.0 1.6 1 1 1 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 CBZ52662.1 - 0.0018 18.3 0.1 0.0026 17.7 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding ApbA PF02558.11 CBZ52662.1 - 0.0059 16.0 0.0 0.011 15.1 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA NAD_binding_7 PF13241.1 CBZ52662.1 - 0.019 15.2 0.0 0.097 12.9 0.0 2.2 1 1 0 1 1 1 0 Putative NAD(P)-binding IlvN PF07991.7 CBZ52662.1 - 0.11 11.8 0.0 0.23 10.7 0.0 1.5 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain UCH PF00443.24 CBZ52663.1 - 2e-69 233.7 0.0 5.3e-69 232.3 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CBZ52663.1 - 5.2e-19 68.7 0.0 1e-08 34.9 0.0 2.1 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.7 CBZ52663.1 - 0.00044 20.5 0.0 0.0012 19.1 0.0 1.8 1 0 0 1 1 1 1 DUSP domain Prim_Zn_Ribbon PF08273.7 CBZ52663.1 - 0.39 10.8 2.3 3.2 7.9 0.0 3.0 3 0 0 3 3 3 0 Zinc-binding domain of primase-helicase LCCL PF03815.14 CBZ52664.1 - 1.1e-75 249.7 4.3 3.1e-26 91.1 0.0 3.6 3 0 0 3 3 3 3 LCCL domain SRCR PF00530.13 CBZ52664.1 - 2.9e-25 88.4 10.9 3.5e-15 56.1 2.4 2.8 2 0 0 2 2 2 2 Scavenger receptor cysteine-rich domain Laminin_G_3 PF13385.1 CBZ52664.1 - 3e-12 47.0 0.0 7.5e-12 45.7 0.0 1.7 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily SRCR_2 PF15494.1 CBZ52664.1 - 9.5e-07 28.9 3.7 0.00018 21.6 0.3 2.5 2 0 0 2 2 2 2 Scavenger receptor cysteine-rich domain Rxt3 PF08642.5 CBZ52664.1 - 0.00012 22.3 0.0 0.027 14.7 0.0 3.2 3 0 0 3 3 3 1 Histone deacetylation protein Rxt3 Pentaxin PF00354.12 CBZ52664.1 - 0.00034 20.1 0.0 0.00072 19.0 0.0 1.5 1 0 0 1 1 1 1 Pentaxin family Sialidase PF02973.11 CBZ52664.1 - 0.0038 16.2 0.0 0.0069 15.3 0.0 1.3 1 0 0 1 1 1 1 Sialidase, N-terminal domain NIF PF03031.13 CBZ52667.1 - 1.6e-39 135.1 0.0 2.7e-39 134.3 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase VRP3 PF03536.10 CBZ52667.1 - 0.065 12.3 0.0 0.1 11.7 0.0 1.2 1 0 0 1 1 1 0 Salmonella virulence-associated 28kDa protein WD40 PF00400.27 CBZ52668.1 - 3.1e-17 61.7 11.3 6.2e-05 22.7 0.0 6.5 7 0 0 7 7 7 4 WD domain, G-beta repeat BBS2_Mid PF14783.1 CBZ52668.1 - 0.033 13.9 0.0 6 6.6 0.0 3.0 3 0 0 3 3 3 0 Ciliary BBSome complex subunit 2, middle region PH_4 PF15404.1 CBZ52668.1 - 0.14 11.6 0.7 0.27 10.7 0.5 1.3 1 0 0 1 1 1 0 Pleckstrin homology domain OATP PF03137.15 CBZ52669.1 - 0.0064 14.6 1.3 0.026 12.5 0.0 2.2 3 0 0 3 3 3 1 Organic Anion Transporter Polypeptide (OATP) family Tetraspannin PF00335.15 CBZ52669.1 - 0.017 14.4 16.9 1 8.5 0.0 2.6 1 1 1 2 2 2 0 Tetraspanin family UPF0542 PF15086.1 CBZ52669.1 - 0.043 13.5 0.0 0.098 12.3 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family UPF0542 DUF4064 PF13273.1 CBZ52669.1 - 3.7 7.7 8.5 0.83 9.7 0.4 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF4064) SpoU_methylase PF00588.14 CBZ52670.1 - 1.8e-17 63.5 0.0 1.6e-07 31.3 0.0 2.4 2 0 0 2 2 2 2 SpoU rRNA Methylase family DUF1681 PF07933.9 CBZ52671.1 - 5.8e-39 133.2 0.0 7.4e-39 132.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) Fis1_TPR_C PF14853.1 CBZ52672.1 - 1.5e-17 63.2 1.0 2.6e-17 62.4 0.0 1.8 2 0 0 2 2 2 1 Fis1 C-terminal tetratricopeptide repeat Fis1_TPR_N PF14852.1 CBZ52672.1 - 1.4e-09 37.0 0.0 2.4e-09 36.3 0.0 1.4 1 0 0 1 1 1 1 Fis1 N-terminal tetratricopeptide repeat TPR_11 PF13414.1 CBZ52672.1 - 0.00014 21.4 0.0 0.00027 20.5 0.0 1.4 1 0 0 1 1 1 1 TPR repeat TPR_2 PF07719.12 CBZ52672.1 - 0.00093 18.9 0.1 0.0073 16.1 0.0 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 CBZ52672.1 - 0.03 14.9 0.2 0.17 12.5 0.1 2.1 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.1 CBZ52672.1 - 0.071 13.4 0.0 0.12 12.6 0.0 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat Neuropep_like PF15161.1 CBZ52672.1 - 0.16 11.4 0.4 0.59 9.6 0.1 2.0 2 0 0 2 2 2 0 Neuropeptide-like Cir_N PF10197.4 CBZ52674.1 - 8.3e-11 41.7 8.8 8.3e-11 41.7 6.1 3.7 4 0 0 4 4 4 1 N-terminal domain of CBF1 interacting co-repressor CIR Porin_3 PF01459.17 CBZ52675.1 - 3.7e-16 59.2 0.7 4.4e-16 59.0 0.5 1.0 1 0 0 1 1 1 1 Eukaryotic porin Rhomboid PF01694.17 CBZ52676.1 - 2.3e-28 99.0 13.1 4.1e-28 98.2 9.1 1.4 1 0 0 1 1 1 1 Rhomboid family DUF3353 PF11833.3 CBZ52677.1 - 0.011 15.1 0.5 0.016 14.6 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3353) CSTF_C PF14304.1 CBZ52677.1 - 0.044 13.0 0.3 0.082 12.2 0.2 1.4 1 0 0 1 1 1 0 Transcription termination and cleavage factor C-terminal GDPD PF03009.12 CBZ52678.1 - 8.7e-18 64.7 0.0 1.6e-17 63.9 0.0 1.4 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family HMG_box PF00505.14 CBZ52678.1 - 0.088 13.0 0.0 0.17 12.2 0.0 1.4 1 0 0 1 1 1 0 HMG (high mobility group) box MFS_1 PF07690.11 CBZ52679.1 - 6e-14 51.5 13.8 8.1e-14 51.0 0.2 2.6 4 0 0 4 4 4 2 Major Facilitator Superfamily MerC PF03203.9 CBZ52680.1 - 1.3e-11 44.8 10.9 1.4e-11 44.7 6.9 1.6 1 1 0 1 1 1 1 MerC mercury resistance protein DUF4131 PF13567.1 CBZ52680.1 - 0.055 12.8 0.3 0.055 12.8 0.2 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Pkinase PF00069.20 CBZ52682.1 - 5.2e-24 84.7 0.0 1.4e-23 83.4 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.1 CBZ52682.1 - 1.4e-17 63.5 0.0 2.3e-17 62.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_Tyr PF07714.12 CBZ52682.1 - 2.5e-07 30.0 0.0 7.6e-07 28.4 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase YpzG PF14139.1 CBZ52682.1 - 0.091 12.7 0.2 4.3 7.3 0.0 2.5 2 0 0 2 2 2 0 YpzG-like protein UIM PF02809.15 CBZ52683.1 - 0.00085 18.6 22.2 0.0065 15.9 0.9 4.4 5 0 0 5 5 5 2 Ubiquitin interaction motif Leu_zip PF15294.1 CBZ52684.1 - 0.0029 16.7 19.0 0.0029 16.7 13.2 2.0 2 0 0 2 2 2 1 Leucine zipper GAS PF13851.1 CBZ52684.1 - 0.01 15.0 38.4 0.027 13.6 6.1 3.1 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding ArdA PF07275.6 CBZ52684.1 - 0.41 10.8 2.1 0.76 10.0 1.5 1.3 1 0 0 1 1 1 0 Antirestriction protein (ArdA) TcdA_TcdB_pore PF12920.2 CBZ52684.1 - 0.5 8.2 3.9 0.7 7.7 2.7 1.1 1 0 0 1 1 1 0 TcdA/TcdB pore forming domain DUF2208 PF09973.4 CBZ52684.1 - 0.7 9.0 0.1 1.2 8.3 0.1 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2208) Atg14 PF10186.4 CBZ52684.1 - 3.3 6.5 31.5 3.8 6.3 11.8 2.2 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Lyase_1 PF00206.15 CBZ52685.1 - 1.5e-50 172.1 0.0 2.4e-50 171.5 0.0 1.2 1 0 0 1 1 1 1 Lyase ASL_C PF08328.6 CBZ52685.1 - 6.9e-42 141.9 0.4 2.3e-41 140.2 0.0 2.0 2 0 0 2 2 2 1 Adenylosuccinate lyase C-terminal Myosin_head PF00063.16 CBZ52686.1 - 7.9e-147 490.2 0.0 1.1e-143 479.8 0.0 2.0 1 1 1 2 2 2 2 Myosin head (motor domain) Zeta_toxin PF06414.7 CBZ52686.1 - 0.00046 19.3 0.2 0.00086 18.4 0.1 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_16 PF13191.1 CBZ52686.1 - 0.023 14.6 0.0 0.053 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.1 CBZ52686.1 - 0.041 14.0 0.0 0.17 12.0 0.0 2.1 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 CBZ52686.1 - 0.054 14.3 0.0 0.15 12.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain CbiA PF01656.18 CBZ52686.1 - 0.059 12.7 0.5 0.14 11.5 0.3 1.6 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain T2SE PF00437.15 CBZ52686.1 - 0.072 11.9 0.0 0.13 11.1 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein UPF0079 PF02367.12 CBZ52686.1 - 0.08 12.5 0.2 0.21 11.2 0.1 1.6 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 ABC_tran PF00005.22 CBZ52686.1 - 0.11 12.8 0.1 0.32 11.2 0.0 1.8 1 0 0 1 1 1 0 ABC transporter AAA_18 PF13238.1 CBZ52686.1 - 0.14 12.4 0.0 0.31 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain CS PF04969.11 CBZ52687.1 - 3.7e-05 24.1 0.0 6.2e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 CS domain TPR_17 PF13431.1 CBZ52688.1 - 9.6e-09 34.7 0.1 0.095 12.9 0.0 5.1 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_11 PF13414.1 CBZ52688.1 - 1.1e-08 34.5 0.4 0.0002 20.9 0.2 4.3 3 3 3 6 6 6 3 TPR repeat TPR_19 PF14559.1 CBZ52688.1 - 1.5e-07 31.6 18.5 5.3e-07 29.8 0.0 4.7 5 2 1 6 6 6 2 Tetratricopeptide repeat TPR_2 PF07719.12 CBZ52688.1 - 1.8e-06 27.3 8.0 0.0029 17.4 0.0 5.4 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_16 PF13432.1 CBZ52688.1 - 2.9e-05 24.6 27.1 0.0016 19.0 0.0 4.7 3 1 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 CBZ52688.1 - 5.1e-05 23.5 26.3 0.00054 20.3 0.4 6.5 6 2 1 7 7 6 2 Tetratricopeptide repeat TPR_8 PF13181.1 CBZ52688.1 - 0.00011 21.6 0.1 0.41 10.5 0.0 4.9 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_1 PF00515.23 CBZ52688.1 - 0.00022 20.6 1.5 0.03 13.9 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.1 CBZ52688.1 - 0.011 15.6 13.2 0.029 14.3 0.0 4.3 4 2 1 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.1 CBZ52688.1 - 0.23 11.9 0.1 0.23 11.9 0.1 4.6 5 1 0 5 5 5 0 Tetratricopeptide repeat TPR_7 PF13176.1 CBZ52688.1 - 0.36 10.7 12.7 1.5 8.7 0.1 4.9 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_20 PF14561.1 CBZ52688.1 - 2.2 8.4 9.7 3.6 7.7 0.0 3.8 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_9 PF13371.1 CBZ52688.1 - 2.6 7.9 10.7 2.5 8.0 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat SNF2_N PF00176.18 CBZ52689.1 - 5.1e-49 166.6 2.2 3.2e-37 127.9 0.0 2.2 1 1 1 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.26 CBZ52689.1 - 1.1e-05 25.2 0.1 4.3e-05 23.3 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain TFIIA PF03153.8 CBZ52689.1 - 0.002 18.1 22.9 0.002 18.1 15.9 2.6 2 0 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit DEAD PF00270.24 CBZ52689.1 - 0.046 13.2 0.0 0.1 12.1 0.0 1.6 1 1 0 1 1 1 0 DEAD/DEAH box helicase HDA2-3 PF11496.3 CBZ52689.1 - 0.24 10.1 0.0 0.24 10.1 0.0 2.2 3 0 0 3 3 3 0 Class II histone deacetylase complex subunits 2 and 3 Citrate_synt PF00285.16 CBZ52690.1 - 5.1e-86 288.6 0.2 6.3e-86 288.3 0.1 1.0 1 0 0 1 1 1 1 Citrate synthase DUF2206 PF09971.4 CBZ52690.1 - 0.19 10.4 0.0 0.28 9.9 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2206) Ribosomal_L27 PF01016.14 CBZ52692.1 - 1.6e-08 34.2 0.1 0.00014 21.5 0.0 2.2 1 1 1 2 2 2 2 Ribosomal L27 protein 14-3-3 PF00244.15 CBZ52694.1 - 3.3e-110 366.7 13.0 3.9e-110 366.5 9.0 1.0 1 0 0 1 1 1 1 14-3-3 protein DUF4085 PF13315.1 CBZ52694.1 - 0.0049 16.2 2.8 0.0049 16.2 1.9 2.1 3 0 0 3 3 3 1 Protein of unknown function (DUF4085) Uteroglobin PF01099.12 CBZ52694.1 - 0.036 13.8 2.3 4.7 7.0 0.4 2.9 2 0 0 2 2 2 0 Uteroglobin family DUF3106 PF11304.3 CBZ52694.1 - 2.8 8.3 10.0 11 6.5 4.3 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF3106) TPR_8 PF13181.1 CBZ52694.1 - 7.7 6.5 8.9 25 4.9 1.1 3.4 2 1 0 2 2 2 0 Tetratricopeptide repeat Pkinase PF00069.20 CBZ52696.1 - 2.1e-54 184.4 0.1 2.9e-52 177.3 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ52696.1 - 6.9e-18 64.6 0.0 2.1e-16 59.8 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 CBZ52696.1 - 1e-06 28.6 0.0 2.7e-05 24.0 0.0 2.3 1 1 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 CBZ52696.1 - 0.0077 15.3 0.0 0.012 14.6 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 CBZ52696.1 - 0.032 13.7 0.1 0.059 12.9 0.1 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase Aconitase_B_N PF11791.3 CBZ52696.1 - 0.042 13.6 0.0 1.7 8.4 0.0 2.2 2 0 0 2 2 2 0 Aconitate B N-terminal domain Kinase-like PF14531.1 CBZ52696.1 - 0.055 12.4 0.0 0.18 10.7 0.0 1.7 2 0 0 2 2 2 0 Kinase-like RIO1 PF01163.17 CBZ52696.1 - 0.055 12.8 0.0 0.095 12.0 0.0 1.4 1 0 0 1 1 1 0 RIO1 family YrbL-PhoP_reg PF10707.4 CBZ52696.1 - 0.2 10.9 0.3 0.89 8.8 0.0 1.9 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL PC_rep PF01851.17 CBZ52697.1 - 2.7e-31 106.0 31.8 1.4e-06 28.2 0.0 8.9 10 0 0 10 10 10 7 Proteasome/cyclosome repeat HEAT_2 PF13646.1 CBZ52697.1 - 5.4e-17 61.8 1.3 2.9e-08 33.8 0.0 4.5 3 1 3 6 6 6 4 HEAT repeats HEAT_EZ PF13513.1 CBZ52697.1 - 7.6e-08 32.6 6.2 0.00015 22.1 0.0 5.2 5 0 0 5 5 5 2 HEAT-like repeat HEAT PF02985.17 CBZ52697.1 - 1.6e-05 24.5 4.7 2.8 8.2 0.1 5.2 5 0 0 5 5 5 2 HEAT repeat HEAT_PBS PF03130.11 CBZ52697.1 - 0.0066 16.8 2.4 4.5 8.0 0.0 4.5 3 0 0 3 3 3 1 PBS lyase HEAT-like repeat UPF0565 PF10561.4 CBZ52697.1 - 2.2 7.1 0.0 2.2 7.1 0.0 2.5 3 0 0 3 3 3 0 Uncharacterised protein family UPF0565 Ribosomal_L13e PF01294.13 CBZ52698.1 - 5e-60 202.0 4.6 6.1e-60 201.7 3.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L13e Ribosomal_S9 PF00380.14 CBZ52699.1 - 5.5e-37 126.7 0.2 6.4e-37 126.4 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Dynein_light PF01221.13 CBZ52700.1 - 4.6e-28 97.0 0.4 4.9e-28 96.9 0.3 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 Ribosomal_L33 PF00471.15 CBZ52701.1 - 1.3e-19 70.2 0.6 1.5e-19 69.9 0.4 1.1 1 0 0 1 1 1 1 Ribosomal protein L33 BTB PF00651.26 CBZ52702.1 - 6e-15 55.1 0.0 1.2e-14 54.2 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain Beach PF02138.13 CBZ52703.1 - 1.1e-62 212.0 0.0 1.9e-40 138.9 0.0 2.4 2 0 0 2 2 2 2 Beige/BEACH domain WD40 PF00400.27 CBZ52703.1 - 1.3e-09 37.5 3.3 0.00012 21.8 0.1 4.3 4 0 0 4 4 4 2 WD domain, G-beta repeat PH_BEACH PF14844.1 CBZ52703.1 - 0.24 11.2 0.0 2.9 7.7 0.0 2.6 2 0 0 2 2 2 0 PH domain associated with Beige/BEACH CBM_20 PF00686.14 CBZ52704.1 - 0.016 14.8 0.0 0.032 13.8 0.0 1.4 1 0 0 1 1 1 0 Starch binding domain DUF3347 PF11827.3 CBZ52705.1 - 0.016 15.1 2.5 0.025 14.5 1.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3347) Cache_2 PF08269.6 CBZ52705.1 - 0.44 10.5 3.5 1.4 8.9 2.4 1.9 1 1 0 1 1 1 0 Cache domain LUC7 PF03194.10 CBZ52707.1 - 3.6e-47 161.0 0.7 3.6e-47 161.0 0.5 1.9 2 0 0 2 2 2 1 LUC7 N_terminus Totivirus_coat PF05518.6 CBZ52707.1 - 0.59 7.8 8.8 0.8 7.4 6.1 1.1 1 0 0 1 1 1 0 Totivirus coat protein Zip PF02535.17 CBZ52707.1 - 1.4 7.8 3.3 2 7.3 2.3 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Asp PF00026.18 CBZ52709.1 - 1.4e-74 251.2 0.0 1.7e-74 250.9 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 CBZ52709.1 - 6.3e-09 35.9 0.0 1e-07 32.0 0.0 2.8 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 CBZ52709.1 - 7.9e-07 28.7 0.0 9.7e-06 25.2 0.0 2.5 2 1 1 3 3 3 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.1 CBZ52709.1 - 0.0059 17.0 0.0 4.8 7.7 0.0 3.1 2 1 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.1 CBZ52709.1 - 0.039 13.7 0.0 0.2 11.4 0.0 2.1 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease DPM3 PF08285.6 CBZ52710.1 - 1e-15 57.3 0.0 1.1e-13 50.7 0.0 2.0 1 1 0 1 1 1 1 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) DUF4234 PF14018.1 CBZ52710.1 - 0.016 14.9 0.1 0.31 10.8 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4234) DUF2759 PF10958.3 CBZ52710.1 - 1.1 8.8 4.8 0.25 10.9 0.9 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2759) Trypsin_2 PF13365.1 CBZ52711.1 - 5.2e-15 55.5 1.4 9e-15 54.7 0.3 2.0 2 0 0 2 2 2 1 Trypsin-like peptidase domain Trypsin PF00089.21 CBZ52711.1 - 1.6e-13 50.7 0.0 3.5e-13 49.6 0.0 1.5 1 0 0 1 1 1 1 Trypsin PDZ_2 PF13180.1 CBZ52711.1 - 7.6e-08 32.1 0.8 1.1e-06 28.3 0.1 2.6 2 0 0 2 2 2 1 PDZ domain PIN PF01850.16 CBZ52711.1 - 0.0055 17.0 0.2 1.7 8.9 0.1 2.5 2 0 0 2 2 2 2 PIN domain PDZ PF00595.19 CBZ52711.1 - 0.092 12.9 0.1 0.37 11.0 0.0 2.0 1 0 0 1 1 1 0 PDZ domain (Also known as DHR or GLGF) NAD_binding_1 PF00175.16 CBZ52712.1 - 1.6e-24 86.5 0.0 2.8e-24 85.7 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 CBZ52712.1 - 3.4e-22 78.4 0.0 4.9e-14 52.2 0.0 2.4 1 1 1 2 2 2 2 Oxidoreductase FAD-binding domain FAD_binding_9 PF08021.6 CBZ52712.1 - 1.7e-05 24.7 0.0 3.7e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Siderophore-interacting FAD-binding domain NAD_binding_6 PF08030.7 CBZ52712.1 - 0.00063 19.6 0.0 0.0038 17.1 0.0 1.9 1 1 1 2 2 2 1 Ferric reductase NAD binding domain Arf PF00025.16 CBZ52715.1 - 1.3e-73 245.9 0.0 1.5e-73 245.7 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 CBZ52715.1 - 2.3e-13 49.8 0.0 2.6e-13 49.6 0.0 1.0 1 0 0 1 1 1 1 Ras family SRPRB PF09439.5 CBZ52715.1 - 3e-12 46.1 0.0 4.3e-12 45.6 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.15 CBZ52715.1 - 1.6e-10 40.2 0.3 5.7e-07 28.5 0.1 2.1 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 CBZ52715.1 - 4e-09 35.9 0.0 4.6e-09 35.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 CBZ52715.1 - 4.7e-08 33.5 0.0 6.2e-08 33.1 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 CBZ52715.1 - 1.7e-06 28.0 0.0 2.4e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 CBZ52715.1 - 0.0042 16.3 0.2 0.033 13.4 0.2 2.1 1 1 0 1 1 1 1 Ferrous iron transport protein B GTP_EFTU PF00009.22 CBZ52715.1 - 0.0065 15.9 0.0 0.41 10.0 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain ArgK PF03308.11 CBZ52715.1 - 0.008 14.9 0.1 0.087 11.5 0.0 2.4 2 1 0 2 2 2 1 ArgK protein SPRY PF00622.23 CBZ52716.1 - 7.1e-05 22.8 1.0 0.73 9.9 0.0 3.7 4 0 0 4 4 4 2 SPRY domain MscS_TM PF12794.2 CBZ52716.1 - 8 4.9 4.5 16 3.9 3.1 1.4 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 Peptidase_C50 PF03568.12 CBZ52717.1 - 4.6e-25 88.1 0.0 8.1e-14 51.0 0.0 2.9 3 0 0 3 3 3 2 Peptidase family C50 Condensation PF00668.15 CBZ52717.1 - 0.49 9.1 0.1 0.94 8.2 0.1 1.4 1 0 0 1 1 1 0 Condensation domain ANTH PF07651.11 CBZ52717.1 - 7 5.2 0.4 13 4.3 0.3 1.4 1 0 0 1 1 1 0 ANTH domain LRR_6 PF13516.1 CBZ52719.1 - 0.011 15.6 0.3 41 4.6 0.0 3.5 3 0 0 3 3 3 0 Leucine Rich repeat SPATIAL PF15256.1 CBZ52719.1 - 1.2 9.1 8.0 0.32 11.0 1.1 2.1 2 0 0 2 2 2 0 SPATIAL FHA PF00498.21 CBZ52720.1 - 6.4e-10 39.0 0.0 1.7e-09 37.6 0.0 1.8 2 0 0 2 2 2 1 FHA domain PARG_cat PF05028.9 CBZ52721.1 - 9.5e-53 179.6 0.0 4.9e-24 85.2 0.0 3.3 3 1 0 3 3 3 3 Poly (ADP-ribose) glycohydrolase (PARG) SET PF00856.23 CBZ52722.1 - 7.3e-09 36.1 0.0 6.3e-08 33.0 0.0 2.1 2 0 0 2 2 2 1 SET domain zf-4CXXC_R1 PF10497.4 CBZ52722.1 - 2.5 8.2 6.9 4.6 7.4 0.3 4.0 5 0 0 5 5 5 0 Zinc-finger domain of monoamine-oxidase A repressor R1 Pkinase PF00069.20 CBZ52723.1 - 1.1e-15 57.5 0.0 1.5e-13 50.5 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Kinase-like PF14531.1 CBZ52723.1 - 2e-05 23.6 0.0 3.5e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_Tyr PF07714.12 CBZ52723.1 - 2.1e-05 23.7 0.0 0.00041 19.5 0.0 2.2 2 1 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.9 CBZ52723.1 - 0.0014 17.7 0.0 0.0025 16.9 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family OCIA PF07051.6 CBZ52723.1 - 0.11 11.9 0.0 0.22 10.9 0.0 1.5 1 0 0 1 1 1 0 Ovarian carcinoma immunoreactive antigen (OCIA) Seadorna_VP7 PF07387.6 CBZ52723.1 - 0.14 10.9 0.1 0.28 9.9 0.0 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 eIF-1a PF01176.14 CBZ52724.1 - 8.8e-29 98.7 0.3 1.3e-28 98.2 0.2 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 Ctr PF04145.10 CBZ52725.1 - 2.2e-29 102.3 3.0 3.6e-29 101.6 1.1 2.1 2 0 0 2 2 2 1 Ctr copper transporter family FAM163 PF15069.1 CBZ52725.1 - 0.052 14.1 6.2 0.17 12.4 0.0 3.2 2 1 1 3 3 3 0 FAM163 family TPR_11 PF13414.1 CBZ52726.1 - 2e-09 36.9 4.8 5.2e-09 35.6 3.4 1.7 1 0 0 1 1 1 1 TPR repeat TPR_9 PF13371.1 CBZ52726.1 - 4.6e-08 32.7 2.2 3e-07 30.1 1.5 2.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.23 CBZ52726.1 - 2e-05 23.9 4.7 0.026 14.1 0.2 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.12 CBZ52726.1 - 0.00012 21.6 5.9 0.032 14.1 0.1 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat Ribosomal_L27e PF01777.13 CBZ52727.1 - 9.2e-27 92.9 7.4 1.2e-26 92.6 5.2 1.2 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.24 CBZ52727.1 - 0.00033 20.2 2.5 0.00033 20.2 1.8 2.0 2 0 0 2 2 2 1 KOW motif Toprim_C_rpt PF13368.1 CBZ52727.1 - 0.14 12.6 2.0 1.8 9.0 0.0 2.5 3 0 0 3 3 3 0 Topoisomerase C-terminal repeat DUF4341 PF14241.1 CBZ52727.1 - 0.15 11.8 0.0 0.2 11.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4341) Rgp1 PF08737.5 CBZ52728.1 - 7.6e-11 41.7 0.1 0.00011 21.3 0.0 3.1 3 0 0 3 3 3 3 Rgp1 Arrestin_N PF00339.24 CBZ52728.1 - 0.0058 16.4 0.2 3.8 7.3 0.2 2.3 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain Prim_Zn_Ribbon PF08273.7 CBZ52729.1 - 0.02 14.9 0.2 4.8 7.3 0.0 2.7 2 1 0 2 2 2 0 Zinc-binding domain of primase-helicase SAG PF04092.8 CBZ52730.1 - 5.8e-11 42.8 11.6 7.6e-07 29.5 0.8 3.3 2 2 0 2 2 2 2 SRS domain Prim_Zn_Ribbon PF08273.7 CBZ52730.1 - 0.19 11.8 1.6 3.3 7.8 0.0 2.7 3 0 0 3 3 3 0 Zinc-binding domain of primase-helicase DZR PF12773.2 CBZ52730.1 - 0.86 9.4 6.2 12 5.8 0.7 2.9 2 0 0 2 2 2 0 Double zinc ribbon zf-RING_3 PF14369.1 CBZ52730.1 - 2.5 8.1 5.1 21 5.2 0.0 3.1 3 0 0 3 3 3 0 zinc-finger Ribosomal_L18ae PF01775.12 CBZ52731.1 - 2e-54 182.7 0.6 2.5e-54 182.4 0.4 1.1 1 0 0 1 1 1 1 Ribosomal L18ae/LX protein domain WD40 PF00400.27 CBZ52733.1 - 3.1e-15 55.3 3.6 1e-05 25.1 0.0 4.6 4 0 0 4 4 4 3 WD domain, G-beta repeat F-box PF00646.28 CBZ52733.1 - 0.015 14.9 0.4 0.1 12.2 0.0 2.4 2 0 0 2 2 2 0 F-box domain COX4 PF02936.9 CBZ52734.1 - 0.00024 20.8 0.0 0.00035 20.3 0.0 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV RRM_1 PF00076.17 CBZ52736.1 - 1.8e-40 136.4 0.0 1.8e-19 69.1 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBZ52736.1 - 3.3e-30 103.8 0.0 2e-16 59.7 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBZ52736.1 - 2.4e-11 43.3 0.0 6.5e-05 22.7 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 CBZ52736.1 - 0.00026 20.8 0.0 0.55 10.1 0.0 2.3 2 0 0 2 2 2 2 RNA binding motif Limkain-b1 PF11608.3 CBZ52736.1 - 0.00069 19.3 0.0 0.2 11.4 0.0 2.3 2 0 0 2 2 2 2 Limkain b1 ERAP1_C PF11838.3 CBZ52738.1 - 0.00024 20.4 0.0 0.00036 19.8 0.0 1.2 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Pkinase PF00069.20 CBZ52742.1 - 2.3e-48 164.6 0.0 1.5e-23 83.2 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ52742.1 - 3.3e-19 68.9 0.1 1.3e-09 37.4 0.1 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 CBZ52742.1 - 0.0011 18.0 0.0 0.25 10.2 0.0 2.3 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 CBZ52742.1 - 0.062 13.0 1.7 0.36 10.5 0.4 2.5 2 1 0 2 2 2 0 Phosphotransferase enzyme family LRR_6 PF13516.1 CBZ52743.1 - 9.7e-13 46.7 9.3 0.3 11.2 0.0 8.0 8 0 0 8 8 8 4 Leucine Rich repeat LRR_4 PF12799.2 CBZ52743.1 - 3.9e-10 39.1 2.0 0.0019 17.7 0.2 6.0 5 2 3 8 8 8 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CBZ52743.1 - 3.3e-06 26.7 8.3 0.0095 15.6 0.8 4.6 3 1 3 6 6 6 3 Leucine rich repeat Pro_isomerase PF00160.16 CBZ52744.1 - 1.1e-27 97.1 0.0 1.4e-27 96.8 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD MMR_HSR1 PF01926.18 CBZ52745.1 - 1e-16 60.9 0.0 2.3e-16 59.8 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 CBZ52745.1 - 8.8e-07 28.5 0.0 0.039 13.3 0.0 2.6 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain DUF258 PF03193.11 CBZ52745.1 - 0.0043 16.2 0.1 0.011 14.8 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function, DUF258 FeoB_N PF02421.13 CBZ52745.1 - 0.014 14.6 0.0 0.057 12.7 0.0 1.9 2 0 0 2 2 2 0 Ferrous iron transport protein B Dynamin_N PF00350.18 CBZ52745.1 - 0.034 13.9 1.2 0.46 10.2 0.0 2.8 3 0 0 3 3 3 0 Dynamin family MobB PF03205.9 CBZ52745.1 - 0.044 13.4 0.0 0.088 12.5 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B ABC_tran PF00005.22 CBZ52745.1 - 0.084 13.1 0.0 0.18 12.0 0.0 1.5 1 0 0 1 1 1 0 ABC transporter Miro PF08477.8 CBZ52745.1 - 0.13 12.8 0.0 0.73 10.3 0.0 2.1 2 0 0 2 2 2 0 Miro-like protein Abhydrolase_5 PF12695.2 CBZ52746.1 - 9.4e-24 83.8 0.0 1.2e-23 83.5 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CBZ52746.1 - 1.4e-09 38.1 0.1 0.00013 21.9 0.0 2.1 1 1 1 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CBZ52746.1 - 1.3e-08 34.6 0.3 4.3e-05 23.1 0.3 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold DUF818 PF05677.7 CBZ52746.1 - 3.9e-07 29.1 0.1 5.4e-07 28.6 0.1 1.1 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) LIP PF03583.9 CBZ52746.1 - 1.4e-05 24.4 0.1 0.021 14.0 0.0 2.1 2 0 0 2 2 2 2 Secretory lipase Abhydrolase_2 PF02230.11 CBZ52746.1 - 5.2e-05 22.7 0.5 0.00036 20.0 0.4 2.2 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.16 CBZ52746.1 - 0.00043 19.5 0.0 0.012 14.8 0.0 2.2 2 0 0 2 2 2 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.3 CBZ52746.1 - 0.00054 19.7 0.5 0.0034 17.1 0.1 2.2 2 0 0 2 2 2 1 Putative lysophospholipase FSH1 PF03959.8 CBZ52746.1 - 0.0038 16.7 0.0 0.0054 16.2 0.0 1.4 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Peptidase_S15 PF02129.13 CBZ52746.1 - 0.17 11.2 0.0 0.5 9.7 0.0 1.6 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) Robl_LC7 PF03259.12 CBZ52747.1 - 2.7e-27 94.1 0.0 3e-27 94.0 0.0 1.0 1 0 0 1 1 1 1 Roadblock/LC7 domain MAPKK1_Int PF08923.5 CBZ52747.1 - 0.0024 17.4 0.1 0.006 16.2 0.1 1.7 1 1 0 1 1 1 1 Mitogen-activated protein kinase kinase 1 interacting Cellulase-like PF12876.2 CBZ52747.1 - 0.041 14.3 0.0 0.048 14.1 0.0 1.1 1 0 0 1 1 1 0 Sugar-binding cellulase-like DUF3248 PF11609.3 CBZ52748.1 - 0.00035 20.2 9.8 1.2 8.8 0.5 5.4 2 1 2 4 4 4 3 Protein of unknown function (DUF3248) Drf_FH1 PF06346.7 CBZ52748.1 - 0.0034 16.8 3.6 0.0072 15.8 2.5 1.6 1 1 0 1 1 1 1 Formin Homology Region 1 IMCp PF12314.3 CBZ52748.1 - 0.023 14.8 0.0 0.09 12.9 0.0 1.9 1 1 0 1 1 1 0 Inner membrane complex protein DUF1629 PF07791.6 CBZ52748.1 - 0.13 12.1 2.9 15 5.4 0.1 3.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1629) Cytadhesin_P30 PF07271.6 CBZ52748.1 - 5 6.3 21.9 6 6.0 6.8 1.9 1 1 1 2 2 2 0 Cytadhesin P30/P32 PX PF00787.19 CBZ52749.1 - 1.3e-09 37.8 0.0 4.1e-05 23.3 0.0 2.6 2 0 0 2 2 2 2 PX domain Dymeclin PF09742.4 CBZ52750.1 - 3.1e-35 121.4 0.0 5.3e-35 120.6 0.0 1.2 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein GcpE PF04551.9 CBZ52752.1 - 1.2e-138 461.7 0.0 1.4e-90 303.6 0.0 2.7 2 1 0 2 2 2 2 GcpE protein UPF0158 PF03682.8 CBZ52752.1 - 0.29 10.7 0.0 0.51 9.9 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0158) ZZ PF00569.12 CBZ52753.1 - 3.6e-10 39.2 5.6 7.3e-10 38.2 3.9 1.5 1 0 0 1 1 1 1 Zinc finger, ZZ type Myb_DNA-binding PF00249.26 CBZ52753.1 - 6.2e-08 32.5 0.0 1.3e-07 31.4 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 CBZ52753.1 - 0.0006 19.8 0.0 0.0015 18.5 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain WD40 PF00400.27 CBZ52754.1 - 3.8e-26 89.9 16.9 1.9e-08 33.8 0.4 7.9 8 0 0 8 8 8 5 WD domain, G-beta repeat TPR_11 PF13414.1 CBZ52754.1 - 0.00097 18.7 1.3 0.016 14.8 0.1 2.4 1 1 1 2 2 2 1 TPR repeat DUF2450 PF10475.4 CBZ52754.1 - 0.88 8.4 0.1 1.3 7.8 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function N-terminal domain (DUF2450) Lipase_3 PF01764.20 CBZ52755.1 - 1.2e-08 34.6 0.0 2.8e-08 33.4 0.0 1.6 1 0 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.3 CBZ52755.1 - 0.17 11.2 0.0 0.27 10.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) TLD PF07534.11 CBZ52756.1 - 7.9e-30 103.6 0.1 1.5e-29 102.7 0.1 1.5 1 0 0 1 1 1 1 TLD GTP_EFTU PF00009.22 CBZ52757.1 - 7.6e-60 201.5 0.0 1.1e-59 201.0 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 CBZ52757.1 - 2.1e-25 88.7 0.2 5.2e-25 87.4 0.0 1.8 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 CBZ52757.1 - 1.8e-15 56.8 0.9 3.3e-15 55.9 0.6 1.5 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 CBZ52757.1 - 2.2e-05 24.3 0.0 7.1e-05 22.7 0.0 1.8 1 1 1 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.1 CBZ52757.1 - 0.00065 19.2 0.3 0.0023 17.5 0.3 1.8 2 0 0 2 2 2 1 Elongation factor Tu domain 4 Miro PF08477.8 CBZ52757.1 - 0.022 15.2 0.0 0.042 14.3 0.0 1.5 1 1 0 1 1 1 0 Miro-like protein cobW PF02492.14 CBZ52757.1 - 0.061 12.7 0.1 0.15 11.4 0.0 1.7 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Rad60-SLD PF11976.3 CBZ52759.1 - 4.3e-05 23.1 0.0 0.00092 18.8 0.0 2.3 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 CBZ52759.1 - 0.00053 19.3 0.0 0.0069 15.7 0.0 2.1 2 0 0 2 2 2 1 Ubiquitin family GABP-alpha PF11620.3 CBZ52759.1 - 0.00056 19.8 0.0 0.001 18.9 0.0 1.4 1 0 0 1 1 1 1 GA-binding protein alpha chain DUF2604 PF10790.4 CBZ52759.1 - 0.082 13.0 0.0 0.18 11.9 0.0 1.5 1 0 0 1 1 1 0 Protein of Unknown function (DUF2604) Kelch_1 PF01344.20 CBZ52760.1 - 8.9e-54 178.8 0.0 2.1e-11 43.2 0.0 6.4 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.1 CBZ52760.1 - 9.9e-36 120.4 0.0 2.5e-07 30.5 0.0 6.6 2 2 4 6 6 6 6 Kelch motif Kelch_4 PF13418.1 CBZ52760.1 - 6e-22 77.1 0.6 0.00033 20.3 0.0 5.6 4 1 1 5 5 5 5 Galactose oxidase, central domain Kelch_3 PF13415.1 CBZ52760.1 - 2.2e-20 72.2 0.3 0.0019 18.3 0.0 7.4 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_2 PF07646.10 CBZ52760.1 - 6.5e-20 70.0 0.2 0.00067 19.3 0.0 6.6 6 0 0 6 6 6 6 Kelch motif BTB_2 PF02214.17 CBZ52760.1 - 3.6e-15 55.9 0.0 9.3e-15 54.6 0.0 1.7 1 0 0 1 1 1 1 BTB/POZ domain Kelch_5 PF13854.1 CBZ52760.1 - 4.4e-11 42.4 1.2 0.18 11.7 0.0 6.5 6 0 0 6 6 6 3 Kelch motif Abhydrolase_6 PF12697.2 CBZ52761.1 - 3.2e-22 79.5 0.2 4.8e-22 78.9 0.2 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CBZ52761.1 - 3.9e-11 42.8 0.0 6.2e-11 42.2 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CBZ52761.1 - 0.00054 19.5 0.1 0.0067 16.0 0.0 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 CBZ52761.1 - 0.00059 19.6 0.3 0.0012 18.5 0.2 1.5 1 0 0 1 1 1 1 Putative lysophospholipase PGAP1 PF07819.8 CBZ52761.1 - 0.00078 19.0 0.0 0.0018 17.8 0.0 1.6 2 0 0 2 2 2 1 PGAP1-like protein Lipase_3 PF01764.20 CBZ52761.1 - 0.0072 15.9 0.1 0.013 15.1 0.1 1.4 1 0 0 1 1 1 1 Lipase (class 3) Thioesterase PF00975.15 CBZ52761.1 - 0.063 13.4 0.0 0.22 11.6 0.0 2.0 2 0 0 2 2 2 0 Thioesterase domain Abhydrolase_2 PF02230.11 CBZ52761.1 - 0.24 10.8 0.4 6.4 6.1 0.0 2.2 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Collagen PF01391.13 CBZ52762.1 - 3.1e-16 58.6 62.7 1.3e-10 40.6 21.1 4.8 3 1 1 4 4 4 2 Collagen triple helix repeat (20 copies) IQ PF00612.22 CBZ52763.1 - 6.6e-12 43.9 15.6 0.0069 15.9 1.0 5.0 4 0 0 4 4 4 4 IQ calmodulin-binding motif TPR_12 PF13424.1 CBZ52765.1 - 7.5e-13 48.2 1.8 1.4e-06 28.1 0.1 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.1 CBZ52765.1 - 1.3e-11 43.9 1.7 4.3e-05 23.0 0.1 2.5 2 0 0 2 2 2 2 TPR repeat SHNi-TPR PF10516.4 CBZ52765.1 - 2.3e-09 36.3 0.1 4.6e-09 35.3 0.0 1.5 1 0 0 1 1 1 1 SHNi-TPR TPR_2 PF07719.12 CBZ52765.1 - 3.2e-09 35.9 6.3 0.0011 18.6 0.4 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 CBZ52765.1 - 1.1e-08 34.3 1.7 0.00047 19.6 0.1 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 CBZ52765.1 - 1.2e-06 29.0 10.6 0.00033 21.2 0.1 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.1 CBZ52765.1 - 0.00028 20.4 1.2 1.3 8.9 0.0 3.8 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 CBZ52765.1 - 0.0003 20.3 1.4 0.09 12.6 0.2 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 CBZ52765.1 - 0.0037 17.7 5.1 1.2 9.9 0.1 3.7 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.1 CBZ52765.1 - 0.016 15.1 1.4 6.8 6.7 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Apc3 PF12895.2 CBZ52765.1 - 0.017 15.2 0.3 1.4 9.1 0.0 2.7 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 CBZ52765.1 - 0.72 10.4 6.4 8.4 7.0 0.1 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF3138 PF11336.3 CBZ52765.1 - 9.7 4.2 14.9 0.2 9.7 0.3 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3138) Brr6_like_C_C PF10104.4 CBZ52767.1 - 1.2e-24 86.3 0.0 1.8e-24 85.8 0.0 1.1 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain KH_1 PF00013.24 CBZ52768.1 - 0.00014 21.4 0.0 0.00037 20.0 0.0 1.7 1 0 0 1 1 1 1 KH domain KH_3 PF13014.1 CBZ52768.1 - 0.018 14.6 0.0 0.043 13.4 0.0 1.7 1 0 0 1 1 1 0 KH domain CytochromB561_N PF09786.4 CBZ52769.1 - 0.11 10.9 9.7 0.21 9.9 6.8 1.4 1 0 0 1 1 1 0 Cytochrome B561, N terminal Pex14_N PF04695.8 CBZ52769.1 - 0.53 10.3 6.2 1.3 9.0 4.3 1.6 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Macoilin PF09726.4 CBZ52769.1 - 0.92 7.7 5.9 1.6 6.9 4.1 1.3 1 0 0 1 1 1 0 Transmembrane protein PCI_Csn8 PF10075.4 CBZ52770.1 - 9.4e-15 54.6 0.0 1.5e-14 54.0 0.0 1.2 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 SAC3_GANP PF03399.11 CBZ52770.1 - 2.8e-10 40.0 0.1 3.9e-10 39.6 0.0 1.2 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family DUF43 PF01861.11 CBZ52770.1 - 0.023 13.6 0.0 0.037 12.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF43 Alg6_Alg8 PF03155.10 CBZ52771.1 - 9.1e-40 136.8 18.5 1.2e-22 80.4 1.9 5.1 4 1 1 5 5 5 5 ALG6, ALG8 glycosyltransferase family DUF2029 PF09594.5 CBZ52771.1 - 0.00017 21.2 9.9 0.00017 21.2 6.9 3.8 4 2 0 5 5 5 1 Protein of unknown function (DUF2029) ALG3 PF05208.8 CBZ52771.1 - 0.041 13.1 1.1 0.068 12.3 0.8 1.3 1 0 0 1 1 1 0 ALG3 protein EF-hand_6 PF13405.1 CBZ52772.1 - 1.7e-07 30.5 0.1 4.5e-05 22.9 0.0 3.2 4 1 0 4 4 4 1 EF-hand domain EF-hand_7 PF13499.1 CBZ52772.1 - 2.6e-06 27.4 0.0 0.0012 18.9 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 CBZ52772.1 - 4.4e-06 25.5 0.2 7.7e-05 21.7 0.0 3.0 4 0 0 4 4 4 1 EF hand EF-hand_8 PF13833.1 CBZ52772.1 - 1.6e-05 24.3 0.1 0.0012 18.4 0.1 3.1 2 2 2 4 4 4 1 EF-hand domain pair EF-hand_5 PF13202.1 CBZ52772.1 - 0.00028 20.0 0.1 0.0015 17.8 0.1 2.2 2 0 0 2 2 2 1 EF hand AP2 PF00847.15 CBZ52773.1 - 7.8e-16 57.9 0.2 1.7e-07 31.2 0.0 2.5 2 0 0 2 2 2 2 AP2 domain GRASP55_65 PF04495.9 CBZ52775.1 - 4.4e-44 149.8 0.0 9.3e-34 116.3 0.0 2.1 1 1 1 2 2 2 2 GRASP55/65 PDZ-like domain PDZ_2 PF13180.1 CBZ52775.1 - 8.2e-08 32.0 0.0 0.0013 18.5 0.0 2.3 2 0 0 2 2 2 2 PDZ domain PDZ PF00595.19 CBZ52775.1 - 1.8e-05 24.8 0.0 0.27 11.4 0.0 2.3 2 0 0 2 2 2 2 PDZ domain (Also known as DHR or GLGF) ATP-synt_ab PF00006.20 CBZ52779.1 - 4.9e-64 215.7 0.0 7.9e-64 215.0 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.18 CBZ52779.1 - 1.3e-23 82.9 1.1 2.3e-23 82.1 0.7 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain ATP-synt_ab_C PF00306.22 CBZ52779.1 - 8.6e-21 74.5 0.1 1.5e-20 73.7 0.1 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain AAA PF00004.24 CBZ52779.1 - 0.0029 17.8 0.0 0.13 12.4 0.0 2.8 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) KaiC PF06745.8 CBZ52779.1 - 0.0053 15.8 0.1 0.0091 15.1 0.1 1.4 1 0 0 1 1 1 1 KaiC MobB PF03205.9 CBZ52779.1 - 0.022 14.4 0.2 4.3 7.0 0.1 3.2 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_25 PF13481.1 CBZ52779.1 - 0.024 14.0 0.1 0.053 12.9 0.1 1.6 1 1 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 CBZ52779.1 - 0.028 14.1 0.0 0.052 13.2 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase DUF258 PF03193.11 CBZ52779.1 - 0.042 13.0 0.1 0.081 12.1 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 NB-ARC PF00931.17 CBZ52779.1 - 0.25 10.1 2.0 0.14 10.9 0.2 1.5 2 0 0 2 2 2 0 NB-ARC domain Abhydrolase_6 PF12697.2 CBZ52780.1 - 1.9e-31 109.7 0.2 4.6e-31 108.4 0.1 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CBZ52780.1 - 1e-18 67.7 0.0 1.7e-12 47.4 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 CBZ52780.1 - 1.9e-17 63.3 0.0 3.6e-16 59.2 0.0 2.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 CBZ52780.1 - 5.7e-06 25.7 0.0 3.8e-05 23.0 0.0 2.1 2 0 0 2 2 2 1 Dienelactone hydrolase family Hydrolase_4 PF12146.3 CBZ52780.1 - 2.6e-05 23.9 0.0 5.7e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase Abhydrolase_4 PF08386.5 CBZ52780.1 - 0.00028 20.7 0.6 0.0011 18.8 0.0 2.3 3 0 0 3 3 3 1 TAP-like protein Ser_hydrolase PF06821.8 CBZ52780.1 - 0.00061 19.4 0.0 0.0011 18.5 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase Abhydrolase_2 PF02230.11 CBZ52780.1 - 0.0041 16.5 0.0 0.037 13.4 0.0 2.4 3 0 0 3 3 3 1 Phospholipase/Carboxylesterase BAAT_C PF08840.6 CBZ52780.1 - 0.11 12.1 0.0 0.5 10.0 0.0 1.9 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal DUF676 PF05057.9 CBZ52780.1 - 0.25 10.5 0.0 0.68 9.1 0.0 1.6 2 0 0 2 2 2 0 Putative serine esterase (DUF676) DNA_pol_A PF00476.15 CBZ52781.1 - 3.8e-56 190.3 0.1 1.6e-55 188.3 0.0 2.1 2 1 0 2 2 2 1 DNA polymerase family A DNA_pol_A_exo1 PF01612.15 CBZ52781.1 - 5.9e-19 68.2 0.0 1.7e-10 40.6 0.0 2.3 2 0 0 2 2 2 2 3'-5' exonuclease AAA_25 PF13481.1 CBZ52781.1 - 2.7e-14 53.0 0.0 7.3e-06 25.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain Toprim_4 PF13662.1 CBZ52781.1 - 8.5e-09 35.3 0.0 2.2e-08 33.9 0.0 1.7 1 0 0 1 1 1 1 Toprim domain Toprim_2 PF13155.1 CBZ52781.1 - 3.7e-06 27.1 0.0 9.6e-06 25.8 0.0 1.7 1 0 0 1 1 1 1 Toprim-like Toprim_3 PF13362.1 CBZ52781.1 - 8.4e-06 25.9 0.0 2.6e-05 24.3 0.0 1.9 1 0 0 1 1 1 1 Toprim domain KaiC PF06745.8 CBZ52781.1 - 0.051 12.6 0.0 0.093 11.8 0.0 1.3 1 0 0 1 1 1 0 KaiC EGF_CA PF07645.10 CBZ52783.1 - 2.4e-28 97.8 78.2 3.9e-10 39.5 6.7 6.2 6 0 0 6 6 6 5 Calcium-binding EGF domain EGF_3 PF12947.2 CBZ52783.1 - 8.1e-22 76.8 59.4 2.1e-06 27.5 6.1 6.1 5 0 0 5 5 5 5 EGF domain cEGF PF12662.2 CBZ52783.1 - 2.5e-18 65.3 48.0 1.8e-07 30.6 1.0 6.8 6 1 0 6 6 6 5 Complement Clr-like EGF-like FXa_inhibition PF14670.1 CBZ52783.1 - 1e-12 47.9 63.1 8e-05 22.6 5.2 6.9 4 2 1 6 6 6 4 Coagulation Factor Xa inhibitory site EGF PF00008.22 CBZ52783.1 - 4.4e-08 32.9 62.1 0.0037 17.1 3.1 7.2 5 2 1 7 7 7 5 EGF-like domain EGF_MSP1_1 PF12946.2 CBZ52783.1 - 3.8e-07 29.7 58.4 8.6e-05 22.2 5.4 6.4 6 1 0 6 6 6 5 MSP1 EGF domain 1 hEGF PF12661.2 CBZ52783.1 - 0.0014 18.5 24.9 0.0061 16.5 0.7 6.1 5 0 0 5 5 5 3 Human growth factor-like EGF CDP-OH_P_transf PF01066.16 CBZ52784.1 - 2.3e-16 59.9 3.0 2.3e-16 59.9 2.1 2.2 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase DUF605 PF04652.11 CBZ52785.1 - 0.38 10.1 43.5 0.0081 15.5 19.1 2.3 2 0 0 2 2 2 0 Vta1 like DUF1179 PF06678.6 CBZ52785.1 - 3.3 8.0 13.1 0.24 11.7 4.3 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1179) Zip PF02535.17 CBZ52788.1 - 2.2e-35 122.2 0.8 9.6e-35 120.0 0.6 1.8 1 1 0 1 1 1 1 ZIP Zinc transporter Ank_5 PF13857.1 CBZ52789.1 - 2.5e-10 40.2 1.7 3.9e-05 23.7 0.0 2.7 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.2 CBZ52789.1 - 6.1e-08 32.8 0.2 0.0078 16.5 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.1 CBZ52789.1 - 1.6e-06 27.8 0.0 0.3 11.4 0.0 3.9 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.25 CBZ52789.1 - 8.8e-06 25.2 0.0 0.013 15.3 0.0 4.0 3 1 0 3 3 3 1 Ankyrin repeat Ank_4 PF13637.1 CBZ52789.1 - 0.0035 17.8 0.1 0.79 10.3 0.0 2.9 1 1 2 3 3 3 1 Ankyrin repeats (many copies) Scaffolding_pro PF11418.3 CBZ52790.1 - 0.11 12.8 0.0 0.17 12.1 0.0 1.2 1 0 0 1 1 1 0 Phi29 scaffolding protein Mesd PF10185.4 CBZ52791.1 - 2e-05 24.3 0.1 2.9e-05 23.8 0.1 1.3 1 1 0 1 1 1 1 Chaperone for wingless signalling and trafficking of LDL receptor AAA_22 PF13401.1 CBZ52792.1 - 4.5e-09 36.5 0.1 1.5e-08 34.8 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 CBZ52792.1 - 3.4e-05 23.8 0.3 0.0002 21.4 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA PF00004.24 CBZ52792.1 - 0.055 13.6 0.0 0.16 12.1 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 CBZ52792.1 - 0.13 11.7 0.1 0.25 10.7 0.1 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain RNase_H2_suC PF08615.6 CBZ52793.1 - 5.7e-11 42.4 0.0 1.1e-09 38.2 0.0 2.2 1 1 0 1 1 1 1 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) GILT PF03227.11 CBZ52797.1 - 1.1e-25 89.5 0.6 1.4e-25 89.2 0.4 1.1 1 0 0 1 1 1 1 Gamma interferon inducible lysosomal thiol reductase (GILT) Herpes_DNAp_acc PF04929.7 CBZ52798.1 - 0.74 8.7 7.3 1.2 7.9 5.0 1.4 1 0 0 1 1 1 0 Herpes DNA replication accessory factor ERCC4 PF02732.10 CBZ52799.1 - 8.7e-20 70.9 0.0 2.2e-19 69.6 0.0 1.8 1 0 0 1 1 1 1 ERCC4 domain Peptidase_M24 PF00557.19 CBZ52800.1 - 2.5e-38 131.7 0.0 4.4e-38 130.9 0.0 1.4 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.13 CBZ52800.1 - 7.1e-22 78.3 0.0 1.9e-21 76.9 0.0 1.7 1 0 0 1 1 1 1 Creatinase/Prolidase N-terminal domain Ank_4 PF13637.1 CBZ52801.1 - 7.7e-39 131.4 3.5 1.4e-12 47.7 0.1 4.1 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_2 PF12796.2 CBZ52801.1 - 9.9e-39 131.5 0.4 4.7e-19 68.5 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 CBZ52801.1 - 2.3e-32 109.1 3.1 1.2e-10 40.6 0.0 4.0 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.1 CBZ52801.1 - 1.4e-27 95.0 2.1 3.7e-09 36.5 0.1 3.5 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 CBZ52801.1 - 1.2e-25 86.9 0.5 6.2e-07 29.0 0.0 3.8 3 0 0 3 3 3 3 Ankyrin repeat Histone PF00125.19 CBZ52802.1 - 4.8e-24 84.2 0.0 6.6e-24 83.8 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 CBZ52802.1 - 0.0011 18.9 0.0 0.002 18.1 0.0 1.4 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Ribosomal_L7Ae PF01248.21 CBZ52803.1 - 3.9e-21 74.3 1.1 7.6e-21 73.4 0.7 1.5 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.6 CBZ52803.1 - 0.0065 16.3 0.0 0.011 15.5 0.0 1.5 1 0 0 1 1 1 1 RNase P subunit Pop3 DUF2161 PF09929.4 CBZ52803.1 - 0.076 12.9 0.1 0.16 11.8 0.1 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2161) TBPIP PF07106.8 CBZ52804.1 - 5.7e-31 107.3 4.3 1.1e-30 106.3 3.0 1.5 1 0 0 1 1 1 1 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Mnd1 PF03962.10 CBZ52804.1 - 0.00036 20.2 3.5 0.00036 20.2 2.4 1.9 2 0 0 2 2 2 1 Mnd1 family Ribosomal_L10 PF00466.15 CBZ52804.1 - 0.11 12.4 0.9 0.41 10.5 0.0 2.1 2 0 0 2 2 2 0 Ribosomal protein L10 DUF4140 PF13600.1 CBZ52804.1 - 0.21 12.0 4.0 0.17 12.3 0.3 2.7 3 0 0 3 3 3 0 N-terminal domain of unknown function (DUF4140) DUF3782 PF12644.2 CBZ52804.1 - 0.21 11.3 2.1 0.22 11.3 0.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3782) RNA_pol_L_2 PF13656.1 CBZ52805.1 - 1.9e-28 97.7 0.0 2.3e-28 97.4 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.19 CBZ52805.1 - 5.8e-10 38.1 0.0 7.7e-10 37.7 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain TAXi_C PF14541.1 CBZ52806.1 - 1.6e-08 34.2 0.0 0.0068 15.9 0.0 3.9 4 0 0 4 4 4 2 Xylanase inhibitor C-terminal Asp PF00026.18 CBZ52806.1 - 0.00017 20.9 0.0 0.0081 15.4 0.0 2.4 2 1 0 2 2 2 1 Eukaryotic aspartyl protease Pol_alpha_B_N PF08418.5 CBZ52806.1 - 2.3 7.6 6.7 1.2 8.6 2.8 1.8 2 0 0 2 2 2 0 DNA polymerase alpha subunit B N-terminal NOGCT PF08155.6 CBZ52807.1 - 3.9e-27 93.6 0.1 7.3e-27 92.8 0.1 1.5 1 0 0 1 1 1 1 NOGCT (NUC087) domain NOG1 PF06858.9 CBZ52807.1 - 9.1e-24 83.1 0.6 2.2e-23 81.8 0.4 1.7 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) MMR_HSR1 PF01926.18 CBZ52807.1 - 2e-17 63.2 0.0 4.1e-17 62.1 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 CBZ52807.1 - 1.5e-11 43.8 0.0 2.3e-11 43.2 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B GTP_EFTU PF00009.22 CBZ52807.1 - 0.012 15.0 0.1 0.048 13.0 0.0 1.9 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 CBZ52807.1 - 0.018 14.8 0.7 5.6 6.7 0.1 2.6 1 1 1 2 2 2 0 Dynamin family Miro PF08477.8 CBZ52807.1 - 0.021 15.3 0.0 0.059 13.8 0.0 1.9 1 0 0 1 1 1 0 Miro-like protein AIG1 PF04548.11 CBZ52807.1 - 0.022 13.8 1.3 0.028 13.5 0.0 1.8 2 1 0 2 2 2 0 AIG1 family DUF258 PF03193.11 CBZ52807.1 - 0.097 11.8 0.0 0.6 9.2 0.0 2.1 1 1 0 1 1 1 0 Protein of unknown function, DUF258 Ribosomal_L22 PF00237.14 CBZ52808.1 - 0.00012 22.0 0.0 0.00025 20.9 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e BPL_LplA_LipB PF03099.14 CBZ52808.1 - 0.14 12.1 0.2 0.32 10.9 0.1 1.6 1 0 0 1 1 1 0 Biotin/lipoate A/B protein ligase family CDC27 PF09507.5 CBZ52809.1 - 0.00024 20.4 56.1 0.00025 20.3 38.9 1.1 1 0 0 1 1 1 1 DNA polymerase subunit Cdc27 SprA-related PF12118.3 CBZ52809.1 - 0.00027 20.3 27.8 0.00038 19.8 19.2 1.3 1 0 0 1 1 1 1 SprA-related family DUF4407 PF14362.1 CBZ52809.1 - 1.2 8.0 21.7 1.4 7.8 15.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Hex_IIIa PF02455.11 CBZ52809.1 - 2.2 6.8 19.8 2.9 6.4 13.7 1.3 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) MIP-T3 PF10243.4 CBZ52809.1 - 3.4 6.0 92.5 4.3 5.6 64.1 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DUF936 PF06075.7 CBZ52809.1 - 5 5.9 35.6 5.7 5.7 24.7 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) Abhydrolase_5 PF12695.2 CBZ52810.1 - 1.8e-16 60.1 1.7 2.2e-16 59.9 0.1 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CBZ52810.1 - 5.2e-10 39.5 4.2 1.5e-08 34.7 0.3 3.2 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 CBZ52810.1 - 0.00054 19.4 0.0 0.01 15.2 0.0 2.3 2 1 0 2 2 2 1 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.16 CBZ52810.1 - 0.00057 19.1 0.0 0.001 18.3 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family LIP PF03583.9 CBZ52810.1 - 0.011 14.9 0.0 0.03 13.5 0.0 1.6 1 1 0 1 1 1 0 Secretory lipase FSH1 PF03959.8 CBZ52810.1 - 0.047 13.1 0.0 0.077 12.4 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase (FSH1) PSS PF03034.10 CBZ52812.1 - 6.8e-94 314.3 0.2 1.5e-93 313.3 0.1 1.5 1 1 0 1 1 1 1 Phosphatidyl serine synthase LSM PF01423.17 CBZ52814.1 - 9.9e-17 60.2 0.1 1.2e-16 60.0 0.1 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 CBZ52814.1 - 3.1e-07 30.2 0.0 4.1e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain SSrecog PF03531.9 CBZ52815.1 - 6.2e-57 192.4 0.1 9.3e-57 191.8 0.1 1.2 1 0 0 1 1 1 1 Structure-specific recognition protein (SSRP1) Rtt106 PF08512.7 CBZ52815.1 - 3.7e-26 90.9 0.2 9.7e-26 89.5 0.0 1.8 2 0 0 2 2 2 1 Histone chaperone Rttp106-like RNase_H2-Ydr279 PF09468.5 CBZ52815.1 - 0.031 13.4 10.1 0.05 12.7 7.0 1.4 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) Nop14 PF04147.7 CBZ52815.1 - 0.52 8.1 31.7 0.69 7.7 22.0 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 CBZ52815.1 - 0.55 8.1 23.3 0.87 7.5 16.1 1.3 1 0 0 1 1 1 0 CDC45-like protein YL1 PF05764.8 CBZ52815.1 - 1.7 8.2 35.4 0.04 13.5 20.2 1.5 2 0 0 2 2 2 0 YL1 nuclear protein SURF2 PF05477.6 CBZ52815.1 - 2.3 7.2 20.4 4 6.5 14.1 1.4 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) BUD22 PF09073.5 CBZ52815.1 - 3.2 6.7 29.0 5 6.0 20.1 1.2 1 0 0 1 1 1 0 BUD22 Herpes_DNAp_acc PF04929.7 CBZ52815.1 - 5.6 5.8 13.5 8 5.3 9.3 1.2 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Apt1 PF10351.4 CBZ52815.1 - 7.4 5.3 13.3 10 4.8 9.2 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain Arm PF00514.18 CBZ52818.1 - 2.4e-13 49.3 0.0 7.3e-05 22.4 0.0 4.4 4 0 0 4 4 4 4 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 CBZ52818.1 - 0.00024 21.3 1.5 0.068 13.4 0.5 2.7 1 1 1 2 2 2 2 HEAT repeats WAPL PF07814.8 CBZ52818.1 - 0.0004 19.2 0.0 0.00078 18.2 0.0 1.5 1 0 0 1 1 1 1 Wings apart-like protein regulation of heterochromatin TetR PF13972.1 CBZ52819.1 - 0.2 11.1 0.1 1.8 7.9 0.0 2.3 2 0 0 2 2 2 0 Bacterial transcriptional repressor DnaJ PF00226.26 CBZ52820.1 - 2.3e-06 27.2 1.1 4.6e-06 26.2 0.1 1.9 2 0 0 2 2 2 1 DnaJ domain Ribosomal_S8 PF00410.14 CBZ52822.1 - 1.9e-18 66.5 0.0 2.2e-18 66.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S8 VID27 PF08553.5 CBZ52823.1 - 1.4 7.0 0.1 2.2 6.3 0.1 1.2 1 0 0 1 1 1 0 VID27 cytoplasmic protein JmjC PF02373.17 CBZ52824.1 - 1.7e-22 79.7 0.0 3e-22 79.0 0.0 1.4 1 0 0 1 1 1 1 JmjC domain, hydroxylase Cupin_8 PF13621.1 CBZ52824.1 - 7.7e-20 71.4 0.0 1.5e-19 70.4 0.0 1.4 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.7 CBZ52824.1 - 0.081 12.1 0.0 0.17 11.1 0.0 1.5 1 0 0 1 1 1 0 Cupin superfamily protein Cwf_Cwc_15 PF04889.7 CBZ52824.1 - 0.091 12.4 7.1 0.1 12.2 0.0 2.4 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Histone PF00125.19 CBZ52825.1 - 1e-24 86.4 0.0 1.3e-24 86.1 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 CBZ52825.1 - 0.00013 21.9 0.0 0.00018 21.5 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 CBZ52826.1 - 9e-34 115.4 0.3 1.4e-33 114.8 0.2 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 CBZ52826.1 - 0.00025 21.1 0.0 0.00037 20.6 0.0 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 CBZ52826.1 - 0.0047 16.9 0.0 0.0097 15.9 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.10 CBZ52826.1 - 0.11 12.3 0.1 0.22 11.3 0.0 1.6 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit Ank_2 PF12796.2 CBZ52827.1 - 4.6e-53 177.5 1.1 1.5e-14 54.0 0.1 4.9 3 1 1 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 CBZ52827.1 - 1.6e-37 125.4 6.0 4.3e-05 23.1 0.0 10.2 9 1 1 10 10 10 7 Ankyrin repeat Ank_5 PF13857.1 CBZ52827.1 - 2.4e-28 97.4 3.5 1.8e-05 24.8 0.0 7.7 3 2 5 8 8 8 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 CBZ52827.1 - 1.4e-23 80.5 4.2 0.022 14.9 0.0 9.5 9 0 0 9 9 9 6 Ankyrin repeat Ank_4 PF13637.1 CBZ52827.1 - 2.5e-19 69.2 2.6 0.0023 18.4 0.0 7.9 3 2 6 9 9 9 7 Ankyrin repeats (many copies) Spt4 PF06093.8 CBZ52828.1 - 1.2e-30 105.2 0.4 1.6e-30 104.7 0.2 1.2 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger PCI PF01399.22 CBZ52829.1 - 1.2e-17 64.1 0.1 7.5e-17 61.5 0.0 2.4 2 1 0 2 2 2 1 PCI domain RabGAP-TBC PF00566.13 CBZ52830.1 - 1.4e-37 129.2 0.0 2.7e-35 121.8 0.0 2.1 1 1 0 1 1 1 1 Rab-GTPase-TBC domain GCC2_GCC3 PF07699.8 CBZ52831.1 - 7.3e-38 127.9 116.7 1.3e-08 34.3 1.9 13.7 12 1 2 14 14 14 10 GCC2 and GCC3 Kringle PF00051.13 CBZ52831.1 - 6.9e-15 54.9 3.9 6.9e-15 54.9 2.7 2.4 2 0 0 2 2 2 1 Kringle domain MAR_sialic_bdg PF10564.4 CBZ52831.1 - 3.2e-09 36.4 11.7 3.9e-05 23.3 0.7 3.2 2 0 0 2 2 2 2 Sialic-acid binding micronemal adhesive repeat DUF2730 PF10805.3 CBZ52831.1 - 0.28 10.9 5.0 3.6 7.3 0.7 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2730) TPT PF03151.11 CBZ52832.1 - 2.6e-36 124.5 19.0 4e-32 110.9 3.7 2.2 2 1 0 2 2 2 2 Triose-phosphate Transporter family EamA PF00892.15 CBZ52832.1 - 3.8e-09 36.6 26.3 5.8e-05 23.1 3.5 2.7 2 1 0 2 2 2 2 EamA-like transporter family UAA PF08449.6 CBZ52832.1 - 5.6e-09 35.3 11.4 1.9e-07 30.2 7.8 2.2 1 1 0 1 1 1 1 UAA transporter family Nuc_sug_transp PF04142.10 CBZ52832.1 - 0.17 10.9 9.8 0.51 9.3 0.2 3.0 3 0 0 3 3 3 0 Nucleotide-sugar transporter Diphthamide_syn PF01866.12 CBZ52833.1 - 3.1e-83 279.5 0.0 4.2e-46 157.6 0.0 2.6 2 1 0 2 2 2 2 Putative diphthamide synthesis protein RNB PF00773.14 CBZ52834.1 - 9.9e-93 310.9 0.1 2e-92 309.9 0.0 1.5 1 0 0 1 1 1 1 RNB domain Pyr_redox_2 PF07992.9 CBZ52836.1 - 0.01 15.7 0.0 0.021 14.6 0.0 1.6 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Dynein_heavy PF03028.10 CBZ52837.1 - 1.5e-220 733.9 0.0 2.9e-220 733.0 0.0 1.5 1 0 0 1 1 1 1 Dynein heavy chain and region D6 of dynein motor AAA_6 PF12774.2 CBZ52837.1 - 9.9e-114 378.6 0.1 5.1e-113 376.2 0.0 2.2 3 0 0 3 3 2 1 Hydrolytic ATP binding site of dynein motor region D1 DHC_N2 PF08393.8 CBZ52837.1 - 4.1e-102 341.7 1.2 4.1e-102 341.7 0.8 2.8 3 0 0 3 3 2 1 Dynein heavy chain, N-terminal region 2 AAA_8 PF12780.2 CBZ52837.1 - 1.4e-98 329.1 0.0 2.7e-98 328.2 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_7 PF12775.2 CBZ52837.1 - 1.4e-85 286.7 1.4 1.5e-75 253.7 0.0 2.8 3 0 0 3 3 2 2 P-loop containing dynein motor region D3 AAA_9 PF12781.2 CBZ52837.1 - 7.9e-82 273.4 0.6 1.5e-81 272.5 0.4 1.5 1 0 0 1 1 1 1 ATP-binding dynein motor region D5 MT PF12777.2 CBZ52837.1 - 1e-77 261.2 15.3 1.8e-77 260.4 10.6 1.4 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_5 PF07728.9 CBZ52837.1 - 1.2e-21 76.8 0.0 8.5e-10 38.4 0.0 6.0 6 1 0 6 6 4 3 AAA domain (dynein-related subfamily) Filamin PF00630.14 CBZ52837.1 - 2.2e-15 57.0 0.0 5.1e-15 55.8 0.0 1.7 1 0 0 1 1 1 1 Filamin/ABP280 repeat Kelch_5 PF13854.1 CBZ52837.1 - 4.9e-11 42.3 0.0 0.0006 19.7 0.0 3.6 3 0 0 3 3 3 2 Kelch motif AAA_22 PF13401.1 CBZ52837.1 - 1.3e-09 38.2 2.1 0.022 14.9 0.0 5.9 5 0 0 5 5 5 2 AAA domain Kelch_4 PF13418.1 CBZ52837.1 - 8.6e-09 35.0 1.9 1.6e-05 24.5 0.1 3.5 3 0 0 3 3 3 1 Galactose oxidase, central domain AAA_17 PF13207.1 CBZ52837.1 - 9.5e-09 36.1 0.0 0.68 10.7 0.0 5.9 5 0 0 5 5 5 2 AAA domain AAA PF00004.24 CBZ52837.1 - 1.1e-08 35.3 0.9 0.53 10.4 0.0 5.7 6 0 0 6 6 5 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 CBZ52837.1 - 1.4e-07 31.6 6.1 0.016 15.2 0.0 6.0 6 0 0 6 6 6 2 AAA ATPase domain AAA_33 PF13671.1 CBZ52837.1 - 1.7e-06 27.9 1.9 0.15 11.9 0.0 4.7 4 0 0 4 4 4 1 AAA domain AAA_18 PF13238.1 CBZ52837.1 - 7.9e-06 26.2 0.5 7.7 6.8 0.0 4.9 4 0 0 4 4 3 0 AAA domain Kelch_6 PF13964.1 CBZ52837.1 - 1.1e-05 25.3 0.2 0.00049 20.1 0.1 3.3 3 0 0 3 3 3 1 Kelch motif UPF0079 PF02367.12 CBZ52837.1 - 1.3e-05 24.8 0.6 0.15 11.7 0.0 3.6 3 0 0 3 3 3 1 Uncharacterised P-loop hydrolase UPF0079 Kelch_2 PF07646.10 CBZ52837.1 - 1.3e-05 24.7 2.1 0.00019 21.0 0.2 3.2 3 0 0 3 3 2 1 Kelch motif Kelch_3 PF13415.1 CBZ52837.1 - 6.7e-05 22.9 9.4 0.0044 17.1 0.1 4.4 4 0 0 4 4 4 1 Galactose oxidase, central domain ABC_tran PF00005.22 CBZ52837.1 - 7.3e-05 23.0 0.0 0.81 9.9 0.0 4.2 3 0 0 3 3 3 1 ABC transporter RNA_helicase PF00910.17 CBZ52837.1 - 0.00011 22.3 0.3 12 6.1 0.0 3.8 3 0 0 3 3 3 0 RNA helicase AAA_14 PF13173.1 CBZ52837.1 - 0.00011 22.1 0.0 3 7.7 0.0 4.8 6 0 0 6 6 4 1 AAA domain NACHT PF05729.7 CBZ52837.1 - 0.0003 20.4 0.5 0.11 12.1 0.0 4.0 4 0 0 4 4 3 1 NACHT domain AAA_19 PF13245.1 CBZ52837.1 - 0.00057 19.5 5.5 2.1 8.1 0.1 5.3 5 0 0 5 5 5 1 Part of AAA domain ATP_bind_1 PF03029.12 CBZ52837.1 - 0.0028 17.2 1.1 3.1 7.2 0.0 3.9 4 0 0 4 4 3 1 Conserved hypothetical ATP binding protein MobB PF03205.9 CBZ52837.1 - 0.0051 16.5 0.1 3.8 7.2 0.0 3.7 3 0 0 3 3 3 1 Molybdopterin guanine dinucleotide synthesis protein B Viral_helicase1 PF01443.13 CBZ52837.1 - 0.0087 15.5 0.0 2.5 7.5 0.0 2.7 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase SRP54 PF00448.17 CBZ52837.1 - 0.01 15.2 1.9 0.79 9.1 0.0 3.9 4 0 0 4 4 4 0 SRP54-type protein, GTPase domain TIG PF01833.19 CBZ52837.1 - 0.012 15.6 0.3 0.025 14.5 0.2 1.6 1 0 0 1 1 1 0 IPT/TIG domain DUF258 PF03193.11 CBZ52837.1 - 0.012 14.7 0.0 0.35 10.0 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function, DUF258 Kelch_1 PF01344.20 CBZ52837.1 - 0.05 13.1 1.2 0.15 11.6 0.1 2.4 3 0 0 3 3 2 0 Kelch motif PduV-EutP PF10662.4 CBZ52837.1 - 0.055 12.9 0.0 1.2 8.6 0.0 2.7 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA PF00004.24 CBZ52838.1 - 1.6e-43 148.0 0.1 3.7e-43 146.8 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 CBZ52838.1 - 1e-06 28.4 0.0 3.9e-06 26.6 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 CBZ52838.1 - 1.8e-06 27.9 0.3 5.9e-06 26.2 0.0 2.0 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 CBZ52838.1 - 7.4e-06 26.1 0.2 0.00032 20.8 0.1 2.4 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 CBZ52838.1 - 2.6e-05 25.0 0.3 0.00018 22.3 0.1 2.3 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 CBZ52838.1 - 5.3e-05 23.2 0.1 0.00028 20.9 0.0 2.1 2 1 0 2 2 2 1 AAA ATPase domain RuvB_N PF05496.7 CBZ52838.1 - 5.9e-05 22.2 0.0 0.00011 21.2 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 CBZ52838.1 - 0.00037 20.1 0.0 0.00079 19.1 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain Filament PF00038.16 CBZ52838.1 - 0.00039 19.9 0.1 0.00092 18.7 0.0 1.6 1 0 0 1 1 1 1 Intermediate filament protein DUF2072 PF09845.4 CBZ52838.1 - 0.00067 19.5 0.4 0.0016 18.3 0.3 1.6 1 0 0 1 1 1 1 Zn-ribbon containing protein (DUF2072) AAA_18 PF13238.1 CBZ52838.1 - 0.0009 19.5 0.4 0.0049 17.1 0.0 2.4 3 1 1 4 4 3 1 AAA domain IstB_IS21 PF01695.12 CBZ52838.1 - 0.0014 18.0 0.0 0.0028 17.0 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_33 PF13671.1 CBZ52838.1 - 0.0018 18.1 0.0 0.0042 16.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 CBZ52838.1 - 0.0032 16.8 0.6 0.12 11.8 0.0 2.7 2 1 1 3 3 3 1 AAA domain Sigma54_activat PF00158.21 CBZ52838.1 - 0.0045 16.4 0.0 0.02 14.3 0.0 2.0 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_3 PF07726.6 CBZ52838.1 - 0.0055 16.3 0.0 0.014 14.9 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.1 CBZ52838.1 - 0.0062 16.5 1.1 0.012 15.5 0.0 2.0 2 1 0 2 2 2 1 AAA domain AAA_14 PF13173.1 CBZ52838.1 - 0.0066 16.3 0.0 0.014 15.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.8 CBZ52838.1 - 0.0092 14.7 0.1 0.023 13.4 0.0 1.6 2 0 0 2 2 2 1 TIP49 C-terminus AAA_24 PF13479.1 CBZ52838.1 - 0.01 15.4 0.0 0.02 14.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 CBZ52838.1 - 0.011 14.9 0.0 0.024 13.8 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.7 CBZ52838.1 - 0.017 14.2 0.0 0.041 12.9 0.0 1.7 1 0 0 1 1 1 0 Zeta toxin PhoH PF02562.11 CBZ52838.1 - 0.019 14.2 0.1 0.12 11.5 0.0 2.2 2 0 0 2 2 2 0 PhoH-like protein NACHT PF05729.7 CBZ52838.1 - 0.022 14.4 0.0 0.64 9.6 0.0 2.3 2 0 0 2 2 2 0 NACHT domain RNA_helicase PF00910.17 CBZ52838.1 - 0.026 14.7 0.0 0.051 13.7 0.0 1.6 1 0 0 1 1 1 0 RNA helicase Arch_ATPase PF01637.13 CBZ52838.1 - 0.027 14.1 0.0 0.15 11.7 0.0 2.3 1 1 0 1 1 1 0 Archaeal ATPase Parvo_NS1 PF01057.12 CBZ52838.1 - 0.04 12.7 0.0 0.067 12.0 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_23 PF13476.1 CBZ52838.1 - 0.049 13.9 1.3 19 5.5 1.7 2.3 2 0 0 2 2 2 0 AAA domain AAA_11 PF13086.1 CBZ52838.1 - 0.065 12.8 0.4 0.37 10.3 0.0 2.3 2 1 0 2 2 2 0 AAA domain AAA_13 PF13166.1 CBZ52838.1 - 0.075 11.4 0.0 1.2 7.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain Sigma54_activ_2 PF14532.1 CBZ52838.1 - 0.1 12.6 0.0 0.31 11.1 0.0 1.9 1 0 0 1 1 1 0 Sigma-54 interaction domain MutS_V PF00488.16 CBZ52839.1 - 1.2e-92 309.5 0.0 2.1e-92 308.7 0.0 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 CBZ52839.1 - 4e-24 85.5 0.9 4e-24 85.5 0.6 2.0 2 0 0 2 2 2 1 MutS domain III MutS_IV PF05190.13 CBZ52839.1 - 1.1e-06 28.7 0.1 2.7e-06 27.4 0.1 1.7 1 0 0 1 1 1 1 MutS family domain IV MutS_II PF05188.12 CBZ52839.1 - 2.4e-05 24.4 0.0 7.5e-05 22.8 0.0 1.8 1 0 0 1 1 1 1 MutS domain II AAA_23 PF13476.1 CBZ52839.1 - 0.029 14.6 1.0 0.13 12.5 0.0 2.4 3 0 0 3 3 3 0 AAA domain NTPase_1 PF03266.10 CBZ52839.1 - 0.042 13.5 0.4 12 5.5 0.0 3.0 3 0 0 3 3 3 0 NTPase CcmD PF04995.9 CBZ52839.1 - 0.14 11.9 0.1 0.14 11.9 0.1 2.5 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) ABM PF03992.11 CBZ52840.1 - 0.0043 17.0 0.0 0.0081 16.1 0.0 1.5 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase Usg PF06233.7 CBZ52841.1 - 0.034 13.9 0.0 0.056 13.3 0.0 1.3 1 0 0 1 1 1 0 Usg-like family zf-Tim10_DDP PF02953.10 CBZ52842.1 - 2.4e-13 49.1 0.1 3e-13 48.8 0.1 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF842 PF05811.8 CBZ52842.1 - 0.053 12.9 0.2 0.08 12.4 0.1 1.3 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) GvpL_GvpF PF06386.6 CBZ52845.1 - 0.047 13.2 0.9 0.86 9.1 0.0 2.1 2 0 0 2 2 2 0 Gas vesicle synthesis protein GvpL/GvpF T4_neck-protein PF11649.3 CBZ52846.1 - 0.19 10.9 0.0 0.28 10.4 0.0 1.1 1 0 0 1 1 1 0 Virus neck protein Det1 PF09737.4 CBZ52847.1 - 0.81 8.3 0.8 1.4 7.6 0.5 1.2 1 0 0 1 1 1 0 De-etiolated protein 1 Det1 RAP PF08373.5 CBZ52848.1 - 2.7e-12 46.2 0.1 6e-12 45.1 0.1 1.6 1 0 0 1 1 1 1 RAP domain DNA_primase_S PF01896.14 CBZ52849.1 - 1.9e-50 170.4 0.0 3.9e-49 166.2 0.0 2.4 2 0 0 2 2 2 1 Eukaryotic and archaeal DNA primase small subunit EF-hand_1 PF00036.27 CBZ52850.1 - 4.3e-30 100.6 13.5 6.2e-09 34.5 0.1 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 CBZ52850.1 - 6.1e-26 90.3 11.4 1.6e-13 50.5 1.1 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 CBZ52850.1 - 1.1e-25 87.1 10.2 4.1e-08 32.4 0.1 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.1 CBZ52850.1 - 4.7e-22 77.3 12.0 3.7e-14 52.0 1.1 3.9 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.1 CBZ52850.1 - 1.5e-16 58.9 11.1 7.2e-05 21.9 0.0 4.6 4 1 0 4 4 4 3 EF hand EF-hand_9 PF14658.1 CBZ52850.1 - 9.9e-15 54.2 0.8 6.3e-07 29.2 0.1 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.2 CBZ52850.1 - 5e-05 22.9 4.8 0.076 12.7 0.0 2.7 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand MgtE_N PF03448.12 CBZ52850.1 - 0.016 15.5 0.7 0.016 15.5 0.5 2.3 2 1 0 2 2 2 0 MgtE intracellular N domain Toprim_2 PF13155.1 CBZ52850.1 - 0.017 15.4 1.4 0.27 11.5 0.1 2.4 1 1 1 2 2 2 0 Toprim-like Caleosin PF05042.8 CBZ52850.1 - 0.094 12.2 0.1 0.85 9.1 0.1 2.3 1 1 0 1 1 1 0 Caleosin related protein FlgD PF03963.9 CBZ52850.1 - 0.097 12.7 1.2 0.16 12.0 0.2 2.0 2 1 0 2 2 2 0 Flagellar hook capping protein - N-terminal region DUF1636 PF07845.6 CBZ52850.1 - 0.13 12.4 0.0 0.38 10.9 0.0 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1636) NaeI PF09126.5 CBZ52850.1 - 0.16 10.6 1.2 0.51 8.9 0.1 2.0 1 1 0 2 2 2 0 Restriction endonuclease NaeI TerB PF05099.8 CBZ52850.1 - 0.16 11.7 4.3 7.9 6.2 0.1 2.9 1 1 3 4 4 4 0 Tellurite resistance protein TerB Ribosomal_60s PF00428.14 CBZ52850.1 - 9.4 6.7 7.7 0.78 10.1 1.8 1.8 2 0 0 2 2 2 0 60s Acidic ribosomal protein Ribosomal_L23 PF00276.15 CBZ52851.1 - 3.4e-08 33.3 0.1 6.6e-08 32.3 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L23 Glycos_transf_2 PF00535.21 CBZ52851.1 - 0.00016 21.3 0.0 0.00036 20.2 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 2 APG9 PF04109.11 CBZ52853.1 - 3.5e-64 217.0 0.8 2.1e-53 181.5 0.0 2.2 2 0 0 2 2 2 2 Autophagy protein Apg9 DUF4014 PF13198.1 CBZ52853.1 - 0.017 15.4 2.0 0.1 12.9 1.4 2.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4014) DnaJ PF00226.26 CBZ52854.1 - 5.6e-21 74.0 0.5 5.6e-21 74.0 0.4 2.0 2 0 0 2 2 2 1 DnaJ domain Sec63 PF02889.11 CBZ52854.1 - 5.2e-20 71.9 0.0 1.3e-13 50.8 0.0 2.2 1 1 1 2 2 2 2 Sec63 Brl domain DUF2615 PF11027.3 CBZ52855.1 - 0.021 14.7 0.0 0.023 14.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2615) ODV-E18 PF10717.4 CBZ52855.1 - 0.077 12.4 0.0 0.094 12.1 0.0 1.2 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 WBS_methylT PF12589.3 CBZ52856.1 - 4.3e-08 33.5 5.2 4.3e-08 33.5 3.6 2.2 2 0 0 2 2 2 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_11 PF08241.7 CBZ52856.1 - 1e-07 32.3 0.0 2.8e-07 30.9 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CBZ52856.1 - 0.00018 21.7 0.0 0.00047 20.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CBZ52856.1 - 0.00048 19.8 0.0 0.0054 16.4 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 CBZ52856.1 - 0.00055 20.4 0.1 0.0013 19.2 0.1 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CBZ52856.1 - 0.0055 16.2 0.0 0.012 15.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain TPMT PF05724.6 CBZ52856.1 - 0.019 14.3 0.0 0.032 13.6 0.0 1.2 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) Methyltransf_26 PF13659.1 CBZ52856.1 - 0.04 13.9 0.6 0.33 10.9 0.4 2.4 1 1 0 1 1 1 0 Methyltransferase domain PUF PF00806.14 CBZ52857.1 - 1.3e-49 162.9 0.5 2.2e-06 26.8 0.0 8.4 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat Rootletin PF15035.1 CBZ52858.1 - 0.0016 18.4 6.6 0.0036 17.2 4.6 1.5 1 0 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion IncA PF04156.9 CBZ52858.1 - 1.3 8.5 7.4 2.5 7.6 5.1 1.3 1 0 0 1 1 1 0 IncA protein Lge1 PF11488.3 CBZ52858.1 - 1.9 8.6 4.9 0.59 10.3 0.4 2.4 2 0 0 2 2 2 0 Transcriptional regulatory protein LGE1 tRNA_anti-codon PF01336.20 CBZ52859.1 - 2.2e-05 24.1 0.8 0.027 14.3 0.0 4.1 4 1 1 5 5 5 2 OB-fold nucleic acid binding domain Rep_fac-A_C PF08646.5 CBZ52859.1 - 0.004 16.8 0.0 0.015 15.0 0.0 1.8 2 0 0 2 2 2 1 Replication factor-A C terminal domain Acetyltransf_1 PF00583.19 CBZ52860.1 - 3.7e-09 36.4 0.0 7.4e-09 35.5 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 CBZ52860.1 - 5.7e-05 23.2 0.0 0.00011 22.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 CBZ52860.1 - 0.0002 21.0 0.0 0.00061 19.5 0.0 1.7 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.1 CBZ52860.1 - 0.016 15.3 0.1 0.041 14.0 0.0 1.7 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 CBZ52860.1 - 0.12 12.1 0.0 2.2 8.1 0.0 2.2 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain IMCp PF12314.3 CBZ52861.1 - 9.3e-21 73.7 68.6 2.1e-10 40.5 10.8 4.4 1 1 3 4 4 4 4 Inner membrane complex protein Sel1 PF08238.7 CBZ52862.1 - 5.3e-42 141.3 33.0 7.3e-08 32.8 0.4 8.3 8 0 0 8 8 8 7 Sel1 repeat TPR_11 PF13414.1 CBZ52862.1 - 6.9e-10 38.4 15.3 0.00014 21.4 0.3 4.3 2 1 2 4 4 4 3 TPR repeat TPR_7 PF13176.1 CBZ52862.1 - 1.8e-06 27.2 10.0 0.12 12.2 0.0 5.4 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.1 CBZ52862.1 - 0.00017 21.8 18.7 0.032 14.5 0.2 5.0 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_12 PF13424.1 CBZ52862.1 - 0.0057 16.5 21.5 0.86 9.5 3.5 5.3 3 2 2 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.1 CBZ52862.1 - 0.009 16.5 18.8 0.36 11.5 0.3 5.9 4 2 3 7 7 6 2 Tetratricopeptide repeat TPR_6 PF13174.1 CBZ52862.1 - 0.04 14.3 14.0 0.3 11.6 0.2 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat MIT PF04212.13 CBZ52862.1 - 0.073 12.9 20.0 3.4 7.6 0.1 5.1 4 2 1 5 5 5 0 MIT (microtubule interacting and transport) domain TPR_17 PF13431.1 CBZ52862.1 - 0.12 12.6 8.0 4.9 7.6 0.0 5.2 3 2 2 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.1 CBZ52862.1 - 0.33 11.6 23.9 0.31 11.7 2.4 4.7 2 2 4 6 6 6 0 Tetratricopeptide repeat SHNi-TPR PF10516.4 CBZ52862.1 - 0.8 9.0 3.2 15 4.9 0.6 2.8 2 0 0 2 2 2 0 SHNi-TPR TPR_1 PF00515.23 CBZ52862.1 - 1.1 9.0 33.5 0.67 9.6 0.3 7.9 9 0 0 9 9 9 0 Tetratricopeptide repeat Apc3 PF12895.2 CBZ52862.1 - 1.9 8.6 11.9 2.2 8.4 2.6 3.4 2 2 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_3 PF07720.7 CBZ52862.1 - 4 7.3 10.9 0.7 9.7 0.7 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat PilJ PF13675.1 CBZ52863.1 - 0.015 15.6 0.4 1.6 9.0 0.1 2.5 2 0 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term Peptidase_C65 PF10275.4 CBZ52864.1 - 2.2e-40 138.5 0.1 4.9e-39 134.1 0.1 2.0 2 0 0 2 2 2 1 Peptidase C65 Otubain OTU PF02338.14 CBZ52864.1 - 0.0075 16.8 0.0 0.036 14.6 0.0 2.0 1 1 0 1 1 1 1 OTU-like cysteine protease COPI_assoc PF08507.5 CBZ52865.1 - 1.4e-05 24.8 6.9 2e-05 24.2 4.8 1.2 1 0 0 1 1 1 1 COPI associated protein Cg6151-P PF10233.4 CBZ52865.1 - 0.057 13.3 3.3 0.14 12.1 2.3 1.7 1 1 0 1 1 1 0 Uncharacterized conserved protein CG6151-P Claudin_2 PF13903.1 CBZ52865.1 - 5.7 6.6 10.3 11 5.6 0.5 2.2 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction LRR_4 PF12799.2 CBZ52867.1 - 6.4e-45 150.1 13.6 1.7e-07 30.6 0.1 10.5 8 1 1 10 10 10 10 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CBZ52867.1 - 2.4e-28 97.6 22.3 6.9e-10 38.5 0.3 8.9 5 2 4 9 9 9 8 Leucine rich repeat LRR_1 PF00560.28 CBZ52867.1 - 1.2e-18 64.2 29.6 0.016 15.1 0.0 14.4 16 0 0 16 16 16 5 Leucine Rich Repeat LRR_9 PF14580.1 CBZ52867.1 - 1.6e-14 53.8 2.6 1.3e-05 24.8 0.0 5.1 2 1 3 5 5 5 4 Leucine-rich repeat LRR_7 PF13504.1 CBZ52867.1 - 5.9e-14 49.7 27.0 2.8 8.5 0.1 14.2 16 0 0 16 16 16 4 Leucine rich repeat LRR_6 PF13516.1 CBZ52867.1 - 8.8e-14 49.9 11.1 2.8 8.2 0.1 12.6 12 1 1 13 13 13 3 Leucine Rich repeat C2 PF00168.25 CBZ52868.1 - 5.2e-31 106.3 0.0 5.2e-06 26.2 0.0 6.6 6 0 0 6 6 6 5 C2 domain FerI PF08151.7 CBZ52868.1 - 0.032 14.2 0.0 0.27 11.2 0.0 2.5 2 0 0 2 2 2 0 FerI (NUC094) domain adh_short PF00106.20 CBZ52869.1 - 1.4e-17 64.0 0.2 3.6e-17 62.8 0.1 1.7 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CBZ52869.1 - 0.00016 21.4 0.0 0.00029 20.5 0.0 1.4 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 CBZ52869.1 - 0.02 14.6 0.0 0.029 14.1 0.0 1.2 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 CBZ52869.1 - 0.087 12.8 0.5 0.28 11.1 0.1 1.8 2 0 0 2 2 2 0 NADH(P)-binding DEAD PF00270.24 CBZ52870.1 - 7.7e-25 87.3 0.0 6.6e-24 84.3 0.0 2.1 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CBZ52870.1 - 6.8e-21 73.9 0.0 1.5e-20 72.8 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain CMS1 PF14617.1 CBZ52870.1 - 0.026 13.6 0.0 0.026 13.6 0.0 1.9 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit CENP-T PF15511.1 CBZ52871.1 - 8.4 5.5 39.1 20 4.2 27.1 1.5 1 1 0 1 1 1 0 Centromere kinetochore component CENP-T DHH PF01368.15 CBZ52873.1 - 0.00015 21.4 0.0 0.00021 20.9 0.0 1.3 1 0 0 1 1 1 1 DHH family Ndc80_HEC PF03801.8 CBZ52874.1 - 1.8e-22 79.4 0.0 1.4e-10 40.8 0.1 2.5 2 0 0 2 2 2 2 HEC/Ndc80p family Spc7 PF08317.6 CBZ52874.1 - 0.0004 19.1 15.4 0.0004 19.1 10.7 2.8 2 1 0 2 2 2 1 Spc7 kinetochore protein Reo_sigmaC PF04582.7 CBZ52874.1 - 0.00044 19.5 2.0 0.00044 19.5 1.4 2.6 2 1 0 2 2 2 1 Reovirus sigma C capsid protein AAA_13 PF13166.1 CBZ52874.1 - 0.00045 18.8 12.9 0.00045 18.8 8.9 2.3 2 0 0 2 2 2 1 AAA domain DUF3349 PF11829.3 CBZ52874.1 - 0.019 15.3 4.2 0.042 14.2 0.1 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF3349) Baculo_PEP_C PF04513.7 CBZ52874.1 - 9.1 6.1 14.0 0.2 11.4 1.1 3.3 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus V_ATPase_I PF01496.14 CBZ52874.1 - 9.4 3.9 29.4 0.2 9.4 7.8 2.2 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Mcm10 PF09332.6 CBZ52875.1 - 2.2e-15 56.8 12.5 2.2e-15 56.8 8.7 3.0 3 0 0 3 3 3 1 Mcm10 replication factor zf-primase PF09329.6 CBZ52875.1 - 3.2e-07 29.8 0.1 6.3e-07 28.9 0.0 1.5 1 0 0 1 1 1 1 Primase zinc finger Borrelia_orfA PF02414.10 CBZ52875.1 - 0.17 11.0 3.1 0.27 10.3 2.2 1.2 1 0 0 1 1 1 0 Borrelia ORF-A PH PF00169.24 CBZ52879.1 - 3.4e-19 68.9 0.6 4.1e-19 68.6 0.4 1.1 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 CBZ52879.1 - 1.4e-09 38.1 1.1 7.3e-09 35.8 0.7 1.8 1 1 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.1 CBZ52879.1 - 1.7e-05 24.8 0.1 3.1e-05 23.9 0.1 1.4 1 1 0 1 1 1 1 Pleckstrin homology domain PH_3 PF14593.1 CBZ52879.1 - 0.00032 20.5 0.2 0.0022 17.8 0.1 1.9 1 1 0 1 1 1 1 PH domain GTP1_OBG PF01018.17 CBZ52880.1 - 8.9e-15 54.6 3.8 6.7e-14 51.8 2.6 2.2 1 1 0 1 1 1 1 GTP1/OBG MMR_HSR1 PF01926.18 CBZ52880.1 - 1.4e-11 44.3 0.0 2.2e-11 43.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 CBZ52880.1 - 0.00014 21.1 0.0 0.0003 20.0 0.0 1.5 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.18 CBZ52880.1 - 0.11 12.3 0.0 0.21 11.4 0.0 1.6 1 1 0 1 1 1 0 Dynamin family Noc2 PF03715.8 CBZ52882.1 - 1.4e-35 122.6 3.7 1.4e-35 122.6 2.6 1.7 2 0 0 2 2 2 1 Noc2p family ABC_membrane PF00664.18 CBZ52883.1 - 4.1e-82 275.6 15.5 1.1e-44 152.9 3.4 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 CBZ52883.1 - 1.6e-67 225.9 0.1 1.7e-33 115.8 0.0 2.8 2 1 0 2 2 2 2 ABC transporter SMC_N PF02463.14 CBZ52883.1 - 7.5e-15 54.7 2.2 2.5e-06 26.8 0.0 4.2 3 1 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 CBZ52883.1 - 3.4e-12 46.9 0.1 0.019 14.9 0.0 4.2 4 0 0 4 4 4 3 AAA domain AAA_22 PF13401.1 CBZ52883.1 - 5.9e-12 45.8 1.0 0.00018 21.6 0.0 3.8 2 2 0 2 2 2 2 AAA domain AAA_16 PF13191.1 CBZ52883.1 - 4.1e-09 36.6 7.1 0.0011 18.9 0.4 3.4 2 2 0 2 2 2 2 AAA ATPase domain DUF258 PF03193.11 CBZ52883.1 - 1.1e-08 34.3 0.8 0.0011 18.2 0.0 2.8 3 0 0 3 3 3 2 Protein of unknown function, DUF258 AAA_25 PF13481.1 CBZ52883.1 - 2e-08 33.9 0.2 0.41 10.0 0.0 4.4 4 0 0 4 4 4 2 AAA domain AAA_17 PF13207.1 CBZ52883.1 - 5.5e-08 33.6 0.1 0.016 16.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 CBZ52883.1 - 2.1e-07 30.3 0.1 0.031 13.8 0.1 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA PF00004.24 CBZ52883.1 - 6.3e-07 29.6 5.2 0.021 15.0 0.3 4.1 2 2 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) SbcCD_C PF13558.1 CBZ52883.1 - 1.3e-06 28.1 2.9 0.0044 16.9 0.1 3.5 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit ABC_ATPase PF09818.4 CBZ52883.1 - 3e-06 26.1 4.7 0.0014 17.3 0.1 3.4 4 0 0 4 4 4 2 Predicted ATPase of the ABC class AAA_5 PF07728.9 CBZ52883.1 - 3.7e-05 23.4 0.5 0.61 9.7 0.0 3.7 5 0 0 5 5 3 2 AAA domain (dynein-related subfamily) Rad17 PF03215.10 CBZ52883.1 - 0.00011 21.1 0.5 0.12 11.0 0.0 2.2 2 0 0 2 2 2 2 Rad17 cell cycle checkpoint protein AAA_10 PF12846.2 CBZ52883.1 - 0.00011 21.7 0.7 3.6 6.9 0.0 4.1 4 0 0 4 4 4 1 AAA-like domain AAA_28 PF13521.1 CBZ52883.1 - 0.00013 21.9 0.4 0.12 12.3 0.2 2.8 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 CBZ52883.1 - 0.00029 20.3 0.1 1.7 8.0 0.0 3.7 3 0 0 3 3 3 1 IstB-like ATP binding protein AAA_18 PF13238.1 CBZ52883.1 - 0.00031 21.0 1.2 0.82 9.9 0.0 2.9 3 0 0 3 3 2 2 AAA domain AAA_14 PF13173.1 CBZ52883.1 - 0.00038 20.3 0.0 2.1 8.2 0.0 3.6 4 0 0 4 4 3 1 AAA domain AAA_19 PF13245.1 CBZ52883.1 - 0.00042 20.0 4.8 0.19 11.4 0.0 3.9 3 1 1 4 4 3 1 Part of AAA domain RNA_helicase PF00910.17 CBZ52883.1 - 0.00049 20.2 0.0 1.7 8.8 0.0 2.9 3 0 0 3 3 2 2 RNA helicase NACHT PF05729.7 CBZ52883.1 - 0.0017 18.0 0.3 2.4 7.8 0.0 3.4 4 0 0 4 4 3 1 NACHT domain Zeta_toxin PF06414.7 CBZ52883.1 - 0.0024 17.0 1.1 1.2 8.1 0.0 3.2 3 0 0 3 3 3 1 Zeta toxin AAA_33 PF13671.1 CBZ52883.1 - 0.0043 16.9 0.1 1.5 8.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain Sigma54_activ_2 PF14532.1 CBZ52883.1 - 0.0056 16.7 0.0 0.24 11.4 0.0 2.8 3 0 0 3 3 2 1 Sigma-54 interaction domain MMR_HSR1 PF01926.18 CBZ52883.1 - 0.0056 16.6 0.5 3.9 7.4 0.0 3.0 2 1 0 2 2 2 0 50S ribosome-binding GTPase G-alpha PF00503.15 CBZ52883.1 - 0.0058 15.3 0.0 0.16 10.6 0.0 2.2 2 0 0 2 2 2 1 G-protein alpha subunit Mg_chelatase PF01078.16 CBZ52883.1 - 0.0061 15.7 1.2 5.6 6.0 0.0 3.6 4 0 0 4 4 4 0 Magnesium chelatase, subunit ChlI NB-ARC PF00931.17 CBZ52883.1 - 0.017 14.0 0.0 2.3 7.0 0.0 2.6 2 0 0 2 2 2 0 NB-ARC domain PduV-EutP PF10662.4 CBZ52883.1 - 0.017 14.5 0.1 2.1 7.8 0.1 2.7 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Miro PF08477.8 CBZ52883.1 - 0.019 15.4 0.3 1.2 9.6 0.0 2.9 2 0 0 2 2 2 0 Miro-like protein PRK PF00485.13 CBZ52883.1 - 0.028 13.9 0.3 6.6 6.2 0.0 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family Viral_helicase1 PF01443.13 CBZ52883.1 - 0.029 13.8 0.7 8.4 5.8 0.1 2.7 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase DUF815 PF05673.8 CBZ52883.1 - 0.036 12.9 0.0 1.8 7.4 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) MobB PF03205.9 CBZ52883.1 - 0.07 12.8 0.5 12 5.5 0.0 3.1 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_23 PF13476.1 CBZ52883.1 - 0.089 13.1 0.4 13 6.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain ATP-synt_ab PF00006.20 CBZ52883.1 - 0.15 11.4 6.6 5.6 6.3 2.3 2.9 2 2 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain DUF87 PF01935.12 CBZ52883.1 - 0.2 11.4 0.7 20 4.9 0.2 3.1 3 0 0 3 3 3 0 Domain of unknown function DUF87 Zip PF02535.17 CBZ52884.1 - 1.5e-30 106.3 18.5 1.4e-14 53.8 8.3 4.1 2 2 0 2 2 2 2 ZIP Zinc transporter CobN-Mg_chel PF02514.11 CBZ52884.1 - 0.44 7.8 0.1 0.61 7.3 0.1 1.0 1 0 0 1 1 1 0 CobN/Magnesium Chelatase Cnd1 PF12717.2 CBZ52885.1 - 1.8e-43 148.4 0.7 2.7e-42 144.6 0.0 3.0 4 0 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 Cohesin_HEAT PF12765.2 CBZ52885.1 - 0.038 13.9 5.8 1.5 8.8 0.0 4.2 4 0 0 4 4 4 0 HEAT repeat associated with sister chromatid cohesion Ribosomal_60s PF00428.14 CBZ52886.1 - 6.2e-26 90.6 7.7 6.2e-26 90.6 5.3 1.5 2 0 0 2 2 2 1 60s Acidic ribosomal protein SET PF00856.23 CBZ52886.1 - 0.0065 16.7 0.1 0.0073 16.6 0.1 1.1 1 0 0 1 1 1 1 SET domain Cyclin_N PF00134.18 CBZ52887.1 - 1.8e-07 30.7 0.2 3.3e-07 29.9 0.1 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Med19 PF10278.4 CBZ52887.1 - 8.4 6.0 11.8 0.26 10.9 3.7 1.7 2 0 0 2 2 2 0 Mediator of RNA pol II transcription subunit 19 CAF1 PF04857.15 CBZ52888.1 - 2.6e-66 223.6 0.4 3.8e-66 223.1 0.3 1.2 1 0 0 1 1 1 1 CAF1 family ribonuclease BT1 PF03092.11 CBZ52890.1 - 1e-78 265.0 14.9 1.5e-78 264.4 10.3 1.1 1 0 0 1 1 1 1 BT1 family MFS_1 PF07690.11 CBZ52890.1 - 0.00088 18.0 1.3 0.00088 18.0 0.9 4.7 1 1 2 4 4 4 2 Major Facilitator Superfamily MMR_HSR1 PF01926.18 CBZ52891.1 - 6.7e-07 29.2 0.0 1.9e-06 27.8 0.0 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 CBZ52891.1 - 0.00018 20.9 0.0 0.78 9.1 0.0 2.6 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain PduV-EutP PF10662.4 CBZ52891.1 - 0.0017 17.8 0.1 0.17 11.3 0.0 2.9 3 0 0 3 3 3 1 Ethanolamine utilisation - propanediol utilisation Dynamin_N PF00350.18 CBZ52891.1 - 0.016 15.0 0.0 1.6 8.4 0.0 2.5 2 0 0 2 2 2 0 Dynamin family MobB PF03205.9 CBZ52891.1 - 0.017 14.8 0.0 0.046 13.4 0.0 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Rad50_zn_hook PF04423.9 CBZ52891.1 - 0.046 13.1 0.1 0.1 12.0 0.0 1.5 1 0 0 1 1 1 0 Rad50 zinc hook motif OB_NTP_bind PF07717.11 CBZ52892.1 - 1.9e-26 92.1 0.0 5.8e-26 90.5 0.0 1.9 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 CBZ52892.1 - 3.8e-24 84.6 1.2 3e-23 81.7 0.0 3.1 3 0 0 3 3 2 1 Helicase associated domain (HA2) Helicase_C PF00271.26 CBZ52892.1 - 8.2e-10 38.4 0.0 1.9e-09 37.2 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 CBZ52892.1 - 2.4e-05 23.8 0.0 0.00011 21.7 0.0 2.0 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 CBZ52892.1 - 0.0007 19.7 0.1 0.0032 17.5 0.1 2.2 1 1 0 1 1 1 1 AAA domain T2SE PF00437.15 CBZ52892.1 - 0.00089 18.2 0.0 0.0016 17.3 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein ResIII PF04851.10 CBZ52892.1 - 0.0018 18.1 0.1 2.6 7.8 0.0 2.9 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Miro PF08477.8 CBZ52892.1 - 0.0068 16.8 0.1 0.47 10.9 0.0 2.7 2 0 0 2 2 2 1 Miro-like protein AAA_14 PF13173.1 CBZ52892.1 - 0.037 13.9 0.0 7.1 6.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.1 CBZ52892.1 - 0.05 13.3 0.1 0.57 9.9 0.0 2.6 3 0 0 3 3 3 0 Part of AAA domain AAA_23 PF13476.1 CBZ52892.1 - 0.087 13.1 0.0 0.087 13.1 0.0 3.2 3 1 1 4 4 3 0 AAA domain KaiC PF06745.8 CBZ52892.1 - 0.099 11.7 0.0 0.19 10.7 0.0 1.4 1 0 0 1 1 1 0 KaiC FtsK_SpoIIIE PF01580.13 CBZ52892.1 - 2.5 7.5 7.6 2.4 7.5 0.1 3.0 2 1 1 3 3 3 0 FtsK/SpoIIIE family MAR_sialic_bdg PF10564.4 CBZ52893.1 - 5.8e-48 160.7 33.3 1.3e-19 69.8 0.7 4.1 3 1 1 4 4 4 4 Sialic-acid binding micronemal adhesive repeat Invasin_D3 PF09134.5 CBZ52893.1 - 0.012 15.4 0.0 0.026 14.3 0.0 1.5 1 0 0 1 1 1 0 Invasin, domain 3 Rad60-SLD_2 PF13881.1 CBZ52894.1 - 0.022 14.6 0.0 0.069 13.0 0.0 1.7 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 CBZ52894.1 - 0.077 12.3 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin family GTP_EFTU PF00009.22 CBZ52895.1 - 2.2e-54 183.7 0.0 3.6e-54 183.0 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 CBZ52895.1 - 1.1e-31 108.8 0.0 4.3e-31 106.9 0.0 2.0 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_II PF14492.1 CBZ52895.1 - 2.9e-31 107.1 0.1 6.1e-31 106.0 0.1 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.19 CBZ52895.1 - 4.4e-25 87.3 0.0 1.8e-24 85.4 0.0 2.0 2 0 0 2 2 2 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 CBZ52895.1 - 1.3e-13 50.8 0.1 3.3e-13 49.5 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 Condensation PF00668.15 CBZ52895.1 - 0.11 11.3 0.0 0.2 10.4 0.0 1.3 1 0 0 1 1 1 0 Condensation domain Nol1_Nop2_Fmu PF01189.12 CBZ52896.1 - 7.2e-10 38.7 0.0 3.8e-06 26.4 0.0 2.3 2 0 0 2 2 2 2 NOL1/NOP2/sun family Apc3 PF12895.2 CBZ52897.1 - 0.081 13.0 3.0 4.5 7.4 0.3 3.2 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.12 CBZ52897.1 - 0.35 10.9 20.3 0.15 12.0 0.4 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.23 CBZ52897.1 - 0.88 9.2 5.0 1.2 8.8 0.1 3.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.1 CBZ52897.1 - 3.3 7.7 11.2 0.96 9.4 2.5 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat PMI_typeI PF01238.16 CBZ52898.1 - 1.9e-56 191.6 0.0 1.6e-49 168.8 0.0 3.1 2 1 0 2 2 2 2 Phosphomannose isomerase type I RBFA PF02033.13 CBZ52898.1 - 0.057 13.4 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 Ribosome-binding factor A Pkinase PF00069.20 CBZ52899.1 - 1e-16 60.8 0.0 1.3e-07 31.0 0.0 3.1 3 1 0 3 3 3 2 Protein kinase domain DUF4605 PF15378.1 CBZ52900.1 - 0.0012 18.4 0.8 0.0015 18.1 0.6 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4605) Herpes_capsid PF06112.6 CBZ52900.1 - 5.9 6.9 8.2 9.6 6.2 2.7 2.1 2 0 0 2 2 2 0 Gammaherpesvirus capsid protein Acetyltransf_1 PF00583.19 CBZ52901.1 - 8.5e-11 41.7 0.0 1.3e-10 41.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 CBZ52901.1 - 4.4e-06 26.7 0.0 6.5e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 CBZ52901.1 - 0.0026 17.8 0.0 0.0036 17.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 CBZ52901.1 - 0.043 13.5 0.1 0.25 11.1 0.0 2.1 1 1 1 2 2 2 0 FR47-like protein Acetyltransf_4 PF13420.1 CBZ52901.1 - 0.12 12.2 0.0 0.18 11.7 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Vip3A_N PF12495.3 CBZ52902.1 - 2.7 7.6 1.4 4.6 6.9 1.0 1.2 1 0 0 1 1 1 0 Vegetative insecticide protein 3A N terminal SAC3_GANP PF03399.11 CBZ52903.1 - 4.9e-45 153.5 0.8 7.2e-45 153.0 0.5 1.2 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 CBZ52903.1 - 0.0037 17.0 0.0 0.0066 16.2 0.0 1.3 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 DUF4096 PF13340.1 CBZ52903.1 - 0.045 13.6 0.1 0.13 12.1 0.0 1.7 1 0 0 1 1 1 0 Putative transposase of IS4/5 family (DUF4096) DnaJ PF00226.26 CBZ52904.1 - 6.9e-22 76.9 0.4 1.5e-21 75.9 0.3 1.6 1 0 0 1 1 1 1 DnaJ domain DUF1977 PF09320.6 CBZ52904.1 - 1.3e-08 35.0 0.4 3e-08 33.8 0.3 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1977) RPT PF13446.1 CBZ52904.1 - 0.088 12.2 0.0 0.34 10.3 0.0 1.9 2 0 0 2 2 2 0 A repeated domain in UCH-protein TPR_14 PF13428.1 CBZ52904.1 - 0.24 12.1 4.3 0.36 11.5 0.2 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF1448 PF07289.6 CBZ52906.1 - 3.5e-14 52.5 0.1 5.5e-14 51.8 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1448) GDA1_CD39 PF01150.12 CBZ52907.1 - 3.7e-21 75.1 0.0 3.5e-17 62.0 0.0 2.4 2 1 0 2 2 2 2 GDA1/CD39 (nucleoside phosphatase) family Carb_anhydrase PF00194.16 CBZ52908.1 - 9.3e-19 67.3 0.5 9.1e-13 47.7 0.0 3.2 3 0 0 3 3 3 3 Eukaryotic-type carbonic anhydrase MMR_HSR1 PF01926.18 CBZ52910.1 - 7.8e-10 38.7 0.0 2.2e-09 37.2 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 CBZ52910.1 - 0.0034 17.2 0.2 0.019 14.8 0.0 2.3 3 0 0 3 3 3 1 Dynamin family DUF258 PF03193.11 CBZ52910.1 - 0.0061 15.7 0.0 0.42 9.7 0.0 2.4 1 1 1 2 2 2 1 Protein of unknown function, DUF258 ImcF-related_N PF14331.1 CBZ52910.1 - 0.052 12.4 0.0 0.14 11.0 0.0 1.7 1 0 0 1 1 1 0 ImcF-related N-terminal domain GTP_EFTU PF00009.22 CBZ52910.1 - 0.072 12.5 0.0 4.3 6.7 0.0 2.4 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Miro PF08477.8 CBZ52910.1 - 0.089 13.2 0.0 0.3 11.5 0.0 1.9 1 0 0 1 1 1 0 Miro-like protein Kazal_2 PF07648.10 CBZ52912.1 - 4.8e-110 359.2 142.2 3e-10 39.8 0.8 13.6 13 0 0 13 13 13 13 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.16 CBZ52912.1 - 3.9e-109 356.5 161.2 1.1e-10 41.2 3.7 13.5 8 4 5 13 13 13 13 Kazal-type serine protease inhibitor domain Preseq_ALAS PF09029.5 CBZ52912.1 - 0.066 13.2 3.6 1.1 9.3 0.4 3.2 2 0 0 2 2 2 0 5-aminolevulinate synthase presequence Syja_N PF02383.13 CBZ52914.1 - 4.5e-27 94.6 0.0 4.3e-15 55.3 0.0 4.0 2 1 0 2 2 2 2 SacI homology domain Myb_DNA-binding PF00249.26 CBZ52915.1 - 0.03 14.3 0.0 0.087 12.8 0.0 1.8 1 0 0 1 1 1 0 Myb-like DNA-binding domain SpoU_methylas_C PF12105.3 CBZ52916.1 - 0.0073 15.8 0.2 0.027 14.0 0.1 1.9 1 0 0 1 1 1 1 SpoU, rRNA methylase, C-terminal RRM_1 PF00076.17 CBZ52916.1 - 0.072 12.7 0.0 0.15 11.6 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2637 PF10935.3 CBZ52916.1 - 0.13 12.1 0.1 0.26 11.2 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2637) DAGK_acc PF00609.14 CBZ52918.1 - 1.1e-14 54.8 0.0 2.4e-14 53.8 0.0 1.6 1 0 0 1 1 1 1 Diacylglycerol kinase accessory domain DAGK_cat PF00781.19 CBZ52918.1 - 1.6e-14 53.4 0.0 3.4e-14 52.4 0.0 1.5 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain NAD_kinase PF01513.16 CBZ52918.1 - 0.15 10.8 0.0 0.29 9.8 0.0 1.4 1 0 0 1 1 1 0 ATP-NAD kinase EF-hand_1 PF00036.27 CBZ52920.1 - 5.8e-17 59.6 4.5 1.1e-05 24.3 0.1 3.6 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.1 CBZ52920.1 - 6.5e-15 55.0 1.6 4.5e-09 36.3 0.4 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 CBZ52920.1 - 1.2e-13 49.7 3.7 0.00075 19.1 0.0 3.8 3 0 0 3 3 3 3 EF-hand domain EF-hand_5 PF13202.1 CBZ52920.1 - 1e-11 43.5 4.1 0.0002 20.5 0.1 3.6 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.1 CBZ52920.1 - 2.4e-10 39.8 6.7 4.9e-05 22.8 0.4 3.4 3 0 0 3 3 3 3 EF-hand domain pair SPARC_Ca_bdg PF10591.4 CBZ52920.1 - 0.018 15.0 2.5 3.2 7.8 0.1 2.5 2 1 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region MARVEL PF01284.18 CBZ52921.1 - 1.4 8.7 12.2 1.1e+02 2.5 8.5 2.6 1 1 0 1 1 1 0 Membrane-associating domain OMPdecase PF00215.19 CBZ52922.1 - 1.3e-27 96.6 0.0 1.9e-26 92.8 0.0 2.0 1 1 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family DUF2859 PF11072.3 CBZ52922.1 - 0.13 11.6 0.0 0.28 10.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2859) Phage_Coat_Gp8 PF05371.7 CBZ52922.1 - 0.22 11.1 2.2 0.68 9.5 1.1 2.2 2 0 0 2 2 2 0 Phage major coat protein, Gp8 VWA PF00092.23 CBZ52924.1 - 5.9e-50 169.4 0.0 6.8e-23 81.3 0.0 3.2 3 0 0 3 3 3 3 von Willebrand factor type A domain VWA_2 PF13519.1 CBZ52924.1 - 2.3e-16 60.3 0.0 2.4e-08 34.2 0.0 3.0 3 0 0 3 3 3 2 von Willebrand factor type A domain Pribosyltran PF00156.22 CBZ52925.1 - 5.7e-12 45.4 0.0 1.5e-11 44.0 0.0 1.7 1 1 0 1 1 1 1 Phosphoribosyl transferase domain zf-met PF12874.2 CBZ52926.1 - 7.1e-07 29.2 0.3 1.5e-06 28.1 0.2 1.6 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 CBZ52926.1 - 0.0012 18.9 1.9 0.0036 17.4 1.3 1.9 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 CBZ52926.1 - 0.035 14.2 0.2 0.072 13.2 0.2 1.4 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) SOBP PF15279.1 CBZ52926.1 - 0.62 10.4 14.1 0.022 15.1 4.3 2.1 2 0 0 2 2 2 0 Sine oculis-binding protein Nucleoporin2 PF04096.9 CBZ52927.1 - 2.3e-33 114.9 0.0 3.5e-33 114.3 0.0 1.3 1 0 0 1 1 1 1 Nucleoporin autopeptidase Nucleoporin_FG PF13634.1 CBZ52927.1 - 3.9e-33 114.0 385.8 2.3e-10 40.7 35.2 13.5 5 2 9 14 14 14 8 Nucleoporin FG repeat region Nup96 PF12110.3 CBZ52927.1 - 1.9e-12 46.9 0.0 3.4e-12 46.0 0.0 1.4 1 0 0 1 1 1 1 Nuclear protein 96 Psu PF07455.6 CBZ52927.1 - 0.24 10.8 0.0 0.47 9.9 0.0 1.4 1 0 0 1 1 1 0 Phage polarity suppression protein (Psu) DUF4403 PF14356.1 CBZ52929.1 - 0.023 13.0 0.1 0.032 12.5 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4403) Amidohydro_4 PF13147.1 CBZ52931.1 - 0.01 15.8 0.5 0.29 11.1 0.0 2.5 2 0 0 2 2 2 0 Amidohydrolase RRM_1 PF00076.17 CBZ52931.1 - 0.017 14.7 0.3 11 5.7 0.0 3.0 3 0 0 3 3 3 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) dCMP_cyt_deam_1 PF00383.17 CBZ52932.1 - 1.9e-16 59.5 0.4 3.3e-16 58.7 0.3 1.4 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Bd3614-deam PF14439.1 CBZ52932.1 - 0.33 10.7 3.7 1.9 8.3 2.5 2.1 1 1 0 1 1 1 0 Bd3614-like deaminase Exo_endo_phos PF03372.18 CBZ52933.1 - 8.1e-23 81.6 1.0 6.2e-21 75.4 0.1 3.2 2 1 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family Pterin_bind PF00809.17 CBZ52934.1 - 5.8e-59 198.9 0.0 8.1e-59 198.5 0.0 1.2 1 0 0 1 1 1 1 Pterin binding enzyme HPPK PF01288.15 CBZ52934.1 - 1.8e-16 60.0 0.0 2.4e-09 36.9 0.0 2.5 2 0 0 2 2 2 2 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) Glycos_transf_2 PF00535.21 CBZ52935.1 - 1.7e-21 76.6 0.0 3.6e-21 75.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.17 CBZ52935.1 - 1.8e-06 28.0 0.2 4e-06 26.8 0.1 1.6 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glyco_transf_7C PF02709.9 CBZ52935.1 - 0.00011 21.5 0.0 0.00026 20.3 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_3 PF13641.1 CBZ52935.1 - 0.0013 18.5 0.0 0.0022 17.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.4 CBZ52935.1 - 0.085 11.9 0.0 0.73 8.8 0.0 2.3 2 1 0 2 2 2 0 Glycosyltransferase like family 2 DUF3161 PF11362.3 CBZ52936.1 - 6e-11 42.1 0.0 1.2e-10 41.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3161) DUF2384 PF09722.5 CBZ52936.1 - 0.13 12.1 1.0 4.3 7.2 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2384) FixG_C PF11614.3 CBZ52937.1 - 0.00072 19.6 0.2 22 5.1 0.0 4.9 5 0 0 5 5 5 2 IG-like fold at C-terminal of FixG, putative oxidoreductase DUF4402 PF14352.1 CBZ52937.1 - 0.001 19.5 7.4 0.99 9.8 0.0 5.4 6 0 0 6 6 6 1 Domain of unknown function (DUF4402) Zn_ribbon_recom PF13408.1 CBZ52937.1 - 0.062 13.5 22.1 2.4 8.4 1.1 5.2 5 0 0 5 5 5 0 Recombinase zinc beta ribbon domain Cadherin-like PF12733.2 CBZ52937.1 - 2.5 8.4 12.8 93 3.4 0.0 6.5 3 2 2 5 5 5 0 Cadherin-like beta sandwich domain Inh PF02974.9 CBZ52937.1 - 6.3 6.4 7.5 65 3.1 0.1 4.2 3 0 0 3 3 3 0 Protease inhibitor Inh Peptidase_M41 PF01434.13 CBZ52938.1 - 3.4e-65 219.5 0.2 6.1e-65 218.6 0.1 1.4 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 CBZ52938.1 - 7.2e-42 142.7 0.0 1.6e-41 141.5 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 CBZ52938.1 - 1.1e-06 29.4 0.0 3.8e-06 27.7 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 CBZ52938.1 - 4e-06 26.9 0.6 1.9e-05 24.7 0.0 2.4 2 1 0 2 2 2 1 AAA ATPase domain AAA_5 PF07728.9 CBZ52938.1 - 5.3e-06 26.2 0.0 2.1e-05 24.2 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) TIP49 PF06068.8 CBZ52938.1 - 5.5e-05 22.0 0.0 0.0001 21.1 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus RuvB_N PF05496.7 CBZ52938.1 - 9.1e-05 21.6 0.1 0.00044 19.3 0.0 2.2 3 0 0 3 3 3 1 Holliday junction DNA helicase ruvB N-terminus AAA_33 PF13671.1 CBZ52938.1 - 0.00095 19.0 0.1 0.0035 17.2 0.0 2.1 2 0 0 2 2 1 1 AAA domain AAA_22 PF13401.1 CBZ52938.1 - 0.00098 19.2 0.2 0.018 15.1 0.0 2.9 2 1 1 3 3 3 1 AAA domain AAA_28 PF13521.1 CBZ52938.1 - 0.0013 18.6 0.1 0.0042 17.0 0.1 1.9 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 CBZ52938.1 - 0.002 17.5 0.1 0.0042 16.5 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein Zeta_toxin PF06414.7 CBZ52938.1 - 0.0024 17.0 0.0 0.0058 15.7 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin AAA_19 PF13245.1 CBZ52938.1 - 0.0026 17.4 0.2 0.0026 17.4 0.1 2.5 3 0 0 3 3 1 1 Part of AAA domain AAA_18 PF13238.1 CBZ52938.1 - 0.018 15.3 0.1 0.077 13.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.16 CBZ52938.1 - 0.032 13.4 0.1 0.14 11.3 0.0 2.1 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI NACHT PF05729.7 CBZ52938.1 - 0.046 13.3 0.0 0.11 12.0 0.0 1.7 1 0 0 1 1 1 0 NACHT domain AAA_25 PF13481.1 CBZ52938.1 - 0.061 12.7 0.3 0.15 11.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain PhoH PF02562.11 CBZ52938.1 - 0.12 11.5 0.1 0.32 10.2 0.1 1.6 1 0 0 1 1 1 0 PhoH-like protein Helicase_C PF00271.26 CBZ52939.1 - 3.2e-15 55.7 0.0 6.7e-15 54.7 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 CBZ52939.1 - 5.4e-13 48.7 0.0 1.9e-12 46.9 0.0 1.9 1 1 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 CBZ52939.1 - 2.7e-05 24.0 0.0 0.00015 21.6 0.0 2.0 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Ribosomal_S21e PF01249.13 CBZ52940.1 - 2.5e-38 129.8 0.0 2.7e-38 129.7 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e Phage_integrase PF00589.17 CBZ52941.1 - 9e-18 64.5 0.0 3.2e-17 62.7 0.0 1.9 2 0 0 2 2 2 1 Phage integrase family DZR PF12773.2 CBZ52941.1 - 0.0011 18.7 5.1 0.0027 17.4 3.5 1.6 1 0 0 1 1 1 1 Double zinc ribbon zinc_ribbon_2 PF13240.1 CBZ52941.1 - 0.0011 18.3 4.4 0.002 17.5 3.1 1.4 1 0 0 1 1 1 1 zinc-ribbon domain zf-ribbon_3 PF13248.1 CBZ52941.1 - 0.009 15.1 4.9 0.018 14.2 3.4 1.4 1 0 0 1 1 1 1 zinc-ribbon domain zf-NADH-PPase PF09297.6 CBZ52941.1 - 0.031 13.7 1.1 0.031 13.7 0.8 2.6 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain DEAD PF00270.24 CBZ52942.1 - 1.3e-32 112.6 0.0 3.1e-32 111.3 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CBZ52942.1 - 2e-17 62.8 0.0 5.8e-11 42.1 0.0 2.6 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.10 CBZ52942.1 - 0.00022 21.0 0.0 0.00022 21.0 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Cupin_8 PF13621.1 CBZ52943.1 - 1.8e-19 70.2 0.0 1e-18 67.7 0.0 2.0 2 0 0 2 2 2 1 Cupin-like domain Na_H_Exchanger PF00999.16 CBZ52944.1 - 3e-36 124.7 26.3 3e-36 124.7 18.2 1.8 2 0 0 2 2 2 1 Sodium/hydrogen exchanger family PALP PF00291.20 CBZ52946.1 - 8.9e-60 202.4 0.4 1.2e-59 202.0 0.3 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CBS PF00571.23 CBZ52946.1 - 2.8e-07 30.2 0.3 0.00026 20.6 0.1 3.3 2 1 0 2 2 2 2 CBS domain GLE1 PF07817.8 CBZ52947.1 - 5.1e-30 104.2 0.9 1e-29 103.2 0.6 1.5 1 0 0 1 1 1 1 GLE1-like protein AAA_23 PF13476.1 CBZ52947.1 - 0.00019 21.8 0.0 0.00019 21.8 0.0 3.8 2 1 0 2 2 1 1 AAA domain MIP-T3 PF10243.4 CBZ52947.1 - 0.0012 17.4 52.0 0.0012 17.4 36.1 4.7 5 0 0 5 5 5 1 Microtubule-binding protein MIP-T3 T2SE PF00437.15 CBZ52947.1 - 0.0016 17.3 0.1 0.003 16.4 0.1 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_29 PF13555.1 CBZ52947.1 - 0.0033 16.9 0.1 0.0071 15.8 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.1 CBZ52947.1 - 0.0065 16.4 0.0 0.0065 16.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain G-alpha PF00503.15 CBZ52947.1 - 0.0068 15.1 0.1 0.0068 15.1 0.1 4.4 3 1 0 3 3 2 1 G-protein alpha subunit AAA PF00004.24 CBZ52947.1 - 0.0069 16.5 0.0 0.021 15.0 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 CBZ52947.1 - 0.0074 17.1 0.1 0.0074 17.1 0.1 4.0 4 1 0 4 4 2 1 AAA domain AAA_22 PF13401.1 CBZ52947.1 - 0.0083 16.2 0.2 0.038 14.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 CBZ52947.1 - 0.13 11.9 1.0 0.59 9.7 0.3 2.3 2 0 0 2 2 2 0 NACHT domain MobB PF03205.9 CBZ52947.1 - 0.14 11.9 0.4 0.36 10.5 0.0 2.0 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B ABC_tran PF00005.22 CBZ52947.1 - 0.17 12.1 0.0 0.17 12.1 0.0 2.8 3 0 0 3 3 2 0 ABC transporter LMBR1 PF04791.11 CBZ52947.1 - 5.8 5.3 9.2 10 4.5 6.4 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein NOG1 PF06858.9 CBZ52948.1 - 5.2e-12 45.4 0.0 2.7e-06 27.1 0.0 2.5 2 0 0 2 2 2 2 Nucleolar GTP-binding protein 1 (NOG1) MMR_HSR1 PF01926.18 CBZ52948.1 - 7.5e-05 22.6 0.0 0.0025 17.7 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_25 PF13481.1 CBZ52948.1 - 0.0059 16.0 2.3 0.038 13.3 0.0 2.9 2 1 1 3 3 3 1 AAA domain FeoB_N PF02421.13 CBZ52948.1 - 0.031 13.5 0.0 0.073 12.3 0.0 1.5 1 0 0 1 1 1 0 Ferrous iron transport protein B 2OG-FeII_Oxy_2 PF13532.1 CBZ52950.1 - 4.7e-31 108.1 0.2 1.1e-27 97.1 0.0 3.3 4 0 0 4 4 4 2 2OG-Fe(II) oxygenase superfamily UbiA PF01040.13 CBZ52951.1 - 1.2e-32 113.1 15.9 1.2e-32 113.1 11.0 2.4 2 1 0 2 2 2 1 UbiA prenyltransferase family ABC1 PF03109.11 CBZ52952.1 - 4.7e-12 45.9 0.0 2.9e-10 40.1 0.0 2.5 2 0 0 2 2 2 1 ABC1 family APH PF01636.18 CBZ52952.1 - 0.096 12.4 7.8 0.27 10.9 5.4 1.8 1 1 0 1 1 1 0 Phosphotransferase enzyme family DUF605 PF04652.11 CBZ52952.1 - 0.75 9.1 11.4 1.5 8.1 7.9 1.4 1 0 0 1 1 1 0 Vta1 like UQ_con PF00179.21 CBZ52953.1 - 2.7e-25 88.4 0.0 3.8e-25 87.9 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 CBZ52953.1 - 0.0076 16.1 0.0 0.0087 15.9 0.0 1.2 1 0 0 1 1 1 1 RWD domain Prok-E2_B PF14461.1 CBZ52953.1 - 0.013 15.3 0.0 0.022 14.4 0.0 1.4 1 0 0 1 1 1 0 Prokaryotic E2 family B Acetyltransf_1 PF00583.19 CBZ52954.1 - 1e-10 41.4 0.0 6.1e-08 32.5 0.0 2.6 2 0 0 2 2 2 2 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 CBZ52954.1 - 7.8e-07 29.2 0.1 9.8e-06 25.6 0.0 2.7 2 1 1 3 3 3 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 CBZ52954.1 - 5.1e-06 26.3 0.1 1.2e-05 25.1 0.1 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 CBZ52954.1 - 4e-05 23.2 0.0 0.00023 20.8 0.0 2.1 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_7 PF13508.1 CBZ52954.1 - 0.0003 20.8 0.0 0.0016 18.5 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 CBZ52954.1 - 0.043 13.6 0.0 0.093 12.6 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Fibroin_P25 PF07294.6 CBZ52954.1 - 0.1 12.0 0.0 0.21 11.0 0.0 1.4 1 0 0 1 1 1 0 Fibroin P25 DUF4131 PF13567.1 CBZ52954.1 - 3 7.2 7.3 5.8 6.2 5.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) DDRGK PF09756.4 CBZ52954.1 - 4.7 6.5 14.1 0.25 10.7 3.0 2.7 2 0 0 2 2 2 0 DDRGK domain ALMT PF11744.3 CBZ52955.1 - 0.09 11.4 0.0 0.13 10.8 0.0 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter Orai-1 PF07856.7 CBZ52955.1 - 0.24 10.9 10.0 0.75 9.3 6.9 1.7 1 1 0 1 1 1 0 Mediator of CRAC channel activity OAD_gamma PF04277.8 CBZ52956.1 - 0.38 11.1 4.4 0.13 12.6 0.5 2.2 2 1 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain DUF4023 PF13215.1 CBZ52957.1 - 0.055 13.2 0.7 0.13 12.0 0.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4023) FixQ PF05545.6 CBZ52957.1 - 0.078 12.6 0.1 0.23 11.1 0.0 1.9 2 0 0 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ HSP20 PF00011.16 CBZ52958.1 - 2.3e-21 75.5 0.6 2.9e-21 75.2 0.4 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family GvpH PF05455.6 CBZ52958.1 - 0.00034 20.2 2.0 0.00065 19.3 0.7 1.8 1 1 1 2 2 2 1 GvpH vATP-synt_AC39 PF01992.11 CBZ52959.1 - 3.6e-61 207.1 0.2 2.5e-30 105.7 0.0 2.0 2 0 0 2 2 2 2 ATP synthase (C/AC39) subunit DUF1077 PF06417.7 CBZ52960.1 - 9e-26 89.6 0.1 4.1e-25 87.5 0.1 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF1077) Bromodomain PF00439.20 CBZ52961.1 - 4.1e-34 116.3 0.0 2.7e-17 62.4 0.0 2.4 2 0 0 2 2 2 2 Bromodomain Rcd1 PF04078.8 CBZ52962.1 - 6.8e-128 425.0 0.7 8e-128 424.7 0.5 1.0 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like Pombe_5TM PF09437.5 CBZ52963.1 - 1.9 7.8 0.0 3.2 7.1 0.0 1.2 1 0 0 1 1 1 0 Pombe specific 5TM protein Lectin_leg-like PF03388.8 CBZ52964.1 - 3.7e-13 49.1 0.0 1e-06 28.0 0.0 2.3 2 0 0 2 2 2 2 Legume-like lectin family AIP3 PF03915.8 CBZ52964.1 - 0.037 12.9 0.4 0.052 12.4 0.3 1.1 1 0 0 1 1 1 0 Actin interacting protein 3 DUF4618 PF15397.1 CBZ52964.1 - 0.15 11.3 1.4 0.17 11.1 0.2 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4618) Acylphosphatase PF00708.13 CBZ52965.1 - 6e-25 87.1 0.1 1e-24 86.4 0.0 1.3 1 0 0 1 1 1 1 Acylphosphatase Rotamase PF00639.16 CBZ52965.1 - 2.1e-22 79.6 0.0 4e-22 78.7 0.0 1.5 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.1 CBZ52965.1 - 1.4e-19 70.5 0.0 2e-19 69.9 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.1 CBZ52965.1 - 5e-07 30.3 0.0 8e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 PPIC-type PPIASE domain TACC PF05010.9 CBZ52965.1 - 0.058 13.1 0.0 0.058 13.1 0.0 1.1 1 0 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC) zf-RING_2 PF13639.1 CBZ52966.1 - 0.045 13.5 6.2 0.092 12.5 4.3 1.6 1 0 0 1 1 1 0 Ring finger domain PHD PF00628.24 CBZ52966.1 - 0.32 10.7 5.9 0.15 11.7 1.1 2.2 2 0 0 2 2 2 0 PHD-finger Prok-RING_1 PF14446.1 CBZ52966.1 - 4.8 6.9 9.8 1.1 8.9 3.9 2.1 2 1 0 2 2 2 0 Prokaryotic RING finger family 1 Ax_dynein_light PF10211.4 CBZ52970.1 - 6.1e-50 169.6 3.3 7.6e-50 169.3 2.3 1.1 1 0 0 1 1 1 1 Axonemal dynein light chain bZIP_2 PF07716.10 CBZ52970.1 - 0.0073 16.0 1.2 0.0073 16.0 0.8 2.5 2 0 0 2 2 2 1 Basic region leucine zipper DivIC PF04977.10 CBZ52970.1 - 0.2 11.1 4.9 0.15 11.5 1.8 2.0 1 1 0 1 1 1 0 Septum formation initiator Mito_fiss_reg PF05308.6 CBZ52970.1 - 0.27 10.5 2.3 0.41 9.9 1.6 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator APG6 PF04111.7 CBZ52970.1 - 0.86 8.5 5.2 1.3 8.0 3.6 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 FlxA PF14282.1 CBZ52970.1 - 1.3 8.9 4.2 2.7 7.9 2.9 1.5 1 0 0 1 1 1 0 FlxA-like protein DUF1192 PF06698.6 CBZ52970.1 - 8.7 6.2 12.3 1.2 9.0 4.6 2.5 3 1 0 3 3 3 0 Protein of unknown function (DUF1192) Toxin_49 PF15529.1 CBZ52971.1 - 0.84 9.6 5.6 39 4.2 0.0 3.9 2 1 2 4 4 4 0 Putative toxin 49 Vps52 PF04129.7 CBZ52975.1 - 8.3e-72 242.3 1.7 5.5e-33 114.2 0.0 3.1 3 0 0 3 3 3 3 Vps52 / Sac2 family Sec3_C PF09763.4 CBZ52975.1 - 2.7e-07 29.1 4.2 3.1e-05 22.3 0.2 2.6 2 1 1 3 3 3 2 Exocyst complex component Sec3 COG6 PF06419.6 CBZ52975.1 - 0.0056 14.8 0.3 0.0056 14.8 0.2 2.2 2 0 0 2 2 2 1 Conserved oligomeric complex COG6 Thioredoxin PF00085.15 CBZ52976.1 - 8.2e-06 25.4 0.0 3.1e-05 23.5 0.0 1.9 2 0 0 2 2 2 1 Thioredoxin FAM176 PF14851.1 CBZ52976.1 - 0.0041 16.8 2.2 0.023 14.3 0.1 2.6 2 0 0 2 2 2 1 FAM176 family Thioredoxin_7 PF13899.1 CBZ52976.1 - 0.023 14.7 0.0 0.076 13.0 0.0 1.8 1 0 0 1 1 1 0 Thioredoxin-like DUF1488 PF07369.6 CBZ52976.1 - 3.3 7.5 11.0 12 5.8 0.5 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1488) TRAP_alpha PF03896.11 CBZ52976.1 - 3.5 6.5 4.0 1.2 8.1 0.2 2.0 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit SAG PF04092.8 CBZ52978.1 - 8.2e-12 45.5 23.6 8.5e-10 39.0 4.3 3.2 3 1 0 3 3 3 2 SRS domain Pilin_PilA PF14245.1 CBZ52978.1 - 0.034 14.6 0.3 0.075 13.5 0.0 1.7 2 0 0 2 2 2 0 Type IV pilin PilA ADK_lid PF05191.9 CBZ52978.1 - 1.1 9.0 4.2 4.9 6.9 0.0 3.2 3 0 0 3 3 3 0 Adenylate kinase, active site lid SAG PF04092.8 CBZ52979.1 - 1.1e-10 42.0 17.6 1.7e-07 31.6 5.3 2.9 2 1 0 2 2 2 2 SRS domain phage_tail_N PF08400.5 CBZ52979.1 - 0.043 13.5 0.5 2.8 7.6 0.3 2.4 2 0 0 2 2 2 0 Prophage tail fibre N-terminal DZR PF12773.2 CBZ52979.1 - 8.7 6.2 8.5 6.7 6.6 0.5 2.8 2 1 0 2 2 2 0 Double zinc ribbon SAG PF04092.8 CBZ52980.1 - 1.1e-11 45.1 22.5 8.7e-09 35.8 4.3 3.3 3 1 0 3 3 3 2 SRS domain Prim_Zn_Ribbon PF08273.7 CBZ52980.1 - 0.064 13.3 0.2 6.8 6.8 0.1 2.4 2 0 0 2 2 2 0 Zinc-binding domain of primase-helicase DZR PF12773.2 CBZ52980.1 - 2.8 7.8 7.8 14 5.5 1.0 2.8 2 1 0 2 2 2 0 Double zinc ribbon SAG PF04092.8 CBZ52981.1 - 8.9e-12 45.4 15.8 2.7e-08 34.2 4.2 3.2 2 1 0 2 2 2 2 SRS domain Prim_Zn_Ribbon PF08273.7 CBZ52981.1 - 0.043 13.8 0.2 4.5 7.4 0.0 2.6 2 0 0 2 2 2 0 Zinc-binding domain of primase-helicase Rep_fac-A_3 PF08661.6 CBZ52981.1 - 0.45 10.4 3.0 9.6 6.1 0.1 2.7 3 0 0 3 3 3 0 Replication factor A protein 3 DZR PF12773.2 CBZ52981.1 - 2.1 8.2 7.8 6.3 6.7 0.5 2.8 2 1 0 2 2 2 0 Double zinc ribbon Kinase-like PF14531.1 CBZ52982.1 - 3.4e-12 45.9 0.2 2e-08 33.5 0.3 3.1 1 1 1 2 2 2 2 Kinase-like Pkinase PF00069.20 CBZ52982.1 - 0.00042 19.5 0.0 0.00081 18.6 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ52982.1 - 0.068 12.2 0.0 0.11 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein tyrosine kinase APH PF01636.18 CBZ52982.1 - 0.13 11.9 0.0 0.35 10.5 0.0 1.8 1 1 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 CBZ52982.1 - 0.18 10.6 0.0 0.26 10.0 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 zf-RING_2 PF13639.1 CBZ52983.1 - 1.2e-07 31.4 13.0 1.2e-07 31.4 9.0 2.7 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4 PF00097.20 CBZ52983.1 - 2.3e-06 27.1 13.9 2.3e-06 27.1 9.6 2.6 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CBZ52983.1 - 9.4e-06 25.5 13.4 9.4e-06 25.5 9.3 2.8 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBZ52983.1 - 6.7e-05 22.5 13.8 6.7e-05 22.5 9.6 2.5 3 0 0 3 3 3 1 zinc-RING finger domain Sina PF03145.11 CBZ52983.1 - 0.00027 20.6 11.5 0.0008 19.1 1.5 3.8 2 1 2 4 4 4 3 Seven in absentia protein family zf-TRAF PF02176.13 CBZ52983.1 - 0.0024 18.2 5.3 0.0024 18.2 3.7 4.0 2 1 2 4 4 4 1 TRAF-type zinc finger zf-C3HC4_4 PF15227.1 CBZ52983.1 - 0.015 15.1 10.6 0.06 13.2 7.3 2.1 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 CBZ52983.1 - 0.05 13.3 7.9 0.16 11.7 5.5 1.9 1 0 0 1 1 1 0 RING-type zinc-finger OTU PF02338.14 CBZ52984.1 - 2e-17 63.9 0.1 3.3e-17 63.2 0.1 1.4 1 0 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.4 CBZ52984.1 - 0.00048 19.5 1.0 0.19 11.0 0.0 2.2 1 1 1 2 2 2 2 Peptidase C65 Otubain Glycos_transf_2 PF00535.21 CBZ52985.1 - 4.2e-20 72.0 0.0 7.7e-20 71.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_2 PF10111.4 CBZ52985.1 - 4.7e-08 32.4 0.0 7.4e-08 31.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Ricin_B_lectin PF00652.17 CBZ52985.1 - 3.1e-06 27.2 2.7 3.1e-05 23.9 1.9 2.3 1 1 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glyco_tranf_2_3 PF13641.1 CBZ52985.1 - 1.9e-05 24.5 0.0 4.1e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_7C PF02709.9 CBZ52985.1 - 2.5e-05 23.6 0.1 2.5e-05 23.6 0.1 2.0 2 0 0 2 2 2 1 N-terminal domain of galactosyltransferase RicinB_lectin_2 PF14200.1 CBZ52985.1 - 0.011 16.0 0.3 0.64 10.4 0.2 2.5 2 0 0 2 2 2 0 Ricin-type beta-trefoil lectin domain-like RAB3GAP2_N PF14655.1 CBZ52987.1 - 7.2e-20 71.3 0.0 2.6e-19 69.5 0.0 1.9 2 0 0 2 2 2 1 Rab3 GTPase-activating protein regulatory subunit N-terminus DUF3446 PF11928.3 CBZ52987.1 - 7.7 6.7 16.6 0.15 12.2 3.8 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF3446) eIF2A PF08662.6 CBZ52988.1 - 2.1e-51 174.3 0.0 1e-28 100.3 0.0 3.6 3 1 1 4 4 4 3 Eukaryotic translation initiation factor eIF2A MIS13 PF08202.6 CBZ52989.1 - 0.0085 15.2 0.6 0.012 14.7 0.4 1.2 1 0 0 1 1 1 1 Mis12-Mtw1 protein family Baculo_PEP_C PF04513.7 CBZ52989.1 - 0.012 15.4 0.3 0.017 14.9 0.2 1.3 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Tmemb_cc2 PF10267.4 CBZ52989.1 - 0.017 13.7 0.8 0.023 13.3 0.6 1.1 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein Leu_zip PF15294.1 CBZ52989.1 - 0.032 13.3 2.4 0.037 13.1 1.7 1.1 1 0 0 1 1 1 0 Leucine zipper Sipho_Gp157 PF05565.6 CBZ52989.1 - 0.067 12.7 0.5 0.09 12.3 0.4 1.3 1 0 0 1 1 1 0 Siphovirus Gp157 DUF4618 PF15397.1 CBZ52989.1 - 0.083 12.2 1.8 0.15 11.3 1.2 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4618) Jnk-SapK_ap_N PF09744.4 CBZ52989.1 - 0.16 11.9 2.2 0.23 11.4 1.4 1.3 1 1 0 1 1 1 0 JNK_SAPK-associated protein-1 SF-assemblin PF06705.6 CBZ52989.1 - 0.18 10.8 1.8 0.28 10.2 1.2 1.3 1 1 0 1 1 1 0 SF-assemblin/beta giardin Tropomyosin_1 PF12718.2 CBZ52989.1 - 0.36 10.6 5.3 0.51 10.1 0.6 2.1 1 1 0 2 2 2 0 Tropomyosin like TMF_DNA_bd PF12329.3 CBZ52989.1 - 6.3 6.6 7.2 1.5 8.6 1.0 2.2 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding ubiquitin PF00240.18 CBZ52990.1 - 1e-06 27.9 0.1 2.6e-06 26.7 0.1 1.6 1 1 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.1 CBZ52990.1 - 2.6e-05 24.3 0.0 8.3e-05 22.7 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD PF11976.3 CBZ52990.1 - 0.022 14.4 0.1 0.15 11.7 0.1 1.9 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like PI3K_rbd PF00794.13 CBZ52990.1 - 0.061 13.2 0.0 0.065 13.1 0.0 1.2 1 0 0 1 1 1 0 PI3-kinase family, ras-binding domain MxiM PF11441.3 CBZ52990.1 - 0.12 12.4 0.0 0.12 12.4 0.0 1.1 1 0 0 1 1 1 0 Pilot protein MxiM UN_NPL4 PF11543.3 CBZ52990.1 - 0.13 12.6 0.0 0.15 12.3 0.0 1.3 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 Tcp10_C PF07202.8 CBZ52991.1 - 1.8e-20 73.2 0.1 3e-20 72.5 0.1 1.3 1 0 0 1 1 1 1 T-complex protein 10 C-terminus Spc7 PF08317.6 CBZ52991.1 - 2.4 6.7 21.0 0.19 10.3 10.2 1.9 2 0 0 2 2 2 0 Spc7 kinetochore protein MFS_1 PF07690.11 CBZ52992.1 - 3.2e-22 78.7 38.9 3.2e-22 78.7 27.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 CBZ52992.1 - 3.2e-06 26.0 35.1 1.4e-05 23.9 24.3 2.1 1 1 0 1 1 1 1 Sugar (and other) transporter OATP PF03137.15 CBZ52992.1 - 3.2e-06 25.4 11.8 0.018 13.1 0.4 3.1 1 1 1 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family Aminotran_1_2 PF00155.16 CBZ52993.1 - 1.8e-68 231.1 0.0 2.4e-68 230.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 CBZ52993.1 - 0.00025 19.8 0.0 0.00044 19.1 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 CBZ52993.1 - 0.0037 15.6 0.0 0.0062 14.8 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.16 CBZ52993.1 - 0.0063 15.6 0.0 0.012 14.7 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase TBP PF00352.16 CBZ52994.1 - 6.3e-52 172.8 0.4 2.2e-28 97.4 0.0 3.0 2 1 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.3 CBZ52994.1 - 0.0036 17.3 0.0 0.026 14.5 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3378) Ferrochelatase PF00762.14 CBZ52997.1 - 6.9e-77 258.5 0.0 1.6e-62 211.3 0.0 2.3 2 0 0 2 2 2 2 Ferrochelatase CbiX PF01903.12 CBZ52997.1 - 0.0095 16.0 0.0 2 8.5 0.0 2.5 2 0 0 2 2 2 2 CbiX ADK PF00406.17 CBZ52998.1 - 1.1e-20 74.0 0.3 4.9e-08 32.9 0.0 3.2 3 0 0 3 3 3 3 Adenylate kinase AAA_17 PF13207.1 CBZ52998.1 - 6.3e-09 36.6 0.1 1.6e-08 35.3 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 CBZ52998.1 - 8.1e-08 32.2 0.6 4.1e-05 23.4 0.0 3.3 1 1 1 2 2 2 1 AAA domain AAA_18 PF13238.1 CBZ52998.1 - 1.3e-06 28.7 0.0 0.0087 16.3 0.0 2.4 2 0 0 2 2 2 2 AAA domain KTI12 PF08433.5 CBZ52998.1 - 0.0047 16.1 0.1 0.0074 15.5 0.1 1.2 1 0 0 1 1 1 1 Chromatin associated protein KTI12 Zeta_toxin PF06414.7 CBZ52998.1 - 0.047 12.7 0.0 0.27 10.2 0.0 2.0 1 1 1 2 2 2 0 Zeta toxin IF3_C PF00707.17 CBZ52999.1 - 0.0016 18.1 0.1 0.0029 17.3 0.0 1.4 1 0 0 1 1 1 1 Translation initiation factor IF-3, C-terminal domain FKBP_C PF00254.23 CBZ53000.1 - 2.7e-10 40.1 0.0 2.7e-08 33.6 0.0 2.2 2 0 0 2 2 2 2 FKBP-type peptidyl-prolyl cis-trans isomerase AAA_23 PF13476.1 CBZ53001.1 - 6.1 7.1 15.7 3.9 7.7 1.7 2.5 2 0 0 2 2 2 0 AAA domain RRM_1 PF00076.17 CBZ53002.1 - 1.3e-06 27.9 0.1 2.7e-06 26.9 0.1 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBZ53002.1 - 3.5e-06 26.8 0.1 7.8e-06 25.7 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBZ53002.1 - 0.086 12.7 0.0 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Lactamase_B_2 PF12706.2 CBZ53003.1 - 6e-10 38.9 0.0 0.003 17.1 0.0 3.3 3 0 0 3 3 3 3 Beta-lactamase superfamily domain Lactamase_B PF00753.22 CBZ53003.1 - 0.0023 17.6 0.5 0.0068 16.0 0.3 1.8 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Kinase-like PF14531.1 CBZ53004.1 - 3.1e-34 118.2 0.0 4.7e-34 117.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase PF00069.20 CBZ53004.1 - 3.4e-21 75.5 0.0 1e-16 60.9 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ53004.1 - 6.2e-06 25.4 0.0 1.1e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Seadorna_VP7 PF07387.6 CBZ53004.1 - 0.03 13.1 0.0 0.05 12.4 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 SAG PF04092.8 CBZ53007.1 - 1.7e-23 83.3 7.6 3.3e-11 43.6 0.1 2.1 2 0 0 2 2 2 2 SRS domain gerPA PF10676.4 CBZ53007.1 - 0.0088 15.8 0.2 0.024 14.4 0.1 1.7 1 0 0 1 1 1 1 Spore germination protein gerPA/gerPF DUF1155 PF06633.6 CBZ53007.1 - 0.1 11.8 0.3 0.21 10.8 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1155) Dot_icm_IcmQ PF09475.5 CBZ53008.1 - 0.82 8.8 0.0 1.4 8.1 0.0 1.3 1 0 0 1 1 1 0 Dot/Icm secretion system protein (dot_icm_IcmQ) WD40 PF00400.27 CBZ53010.1 - 1.5e-47 157.8 15.0 3.1e-07 30.0 0.1 11.9 12 0 0 12 12 12 9 WD domain, G-beta repeat PQQ_2 PF13360.1 CBZ53010.1 - 9.8e-05 21.9 0.0 0.047 13.1 0.0 3.1 1 1 2 3 3 3 2 PQQ-like domain PQQ_3 PF13570.1 CBZ53010.1 - 0.011 15.9 7.0 11 6.4 0.0 6.5 8 1 1 9 9 9 0 PQQ-like domain WD40 PF00400.27 CBZ53011.1 - 7.9e-12 44.5 8.3 7.8e-09 35.0 0.0 4.2 5 0 0 5 5 5 2 WD domain, G-beta repeat DUF2330 PF10092.4 CBZ53011.1 - 0.054 12.3 0.1 0.13 11.1 0.0 1.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2330) PDEase_I PF00233.14 CBZ53012.1 - 1.7e-40 139.2 0.8 2.7e-40 138.6 0.6 1.3 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase RRP7 PF12923.2 CBZ53013.1 - 2.7e-18 66.2 3.9 1.4e-08 34.7 0.0 2.5 2 0 0 2 2 2 2 Ribosomal RNA-processing protein 7 (RRP7) G-patch PF01585.18 CBZ53014.1 - 0.0005 19.8 0.5 0.0013 18.5 0.3 1.7 1 0 0 1 1 1 1 G-patch domain Bcr-Abl_Oligo PF09036.5 CBZ53014.1 - 0.39 10.6 4.1 0.15 12.0 0.2 2.3 2 0 0 2 2 2 0 Bcr-Abl oncoprotein oligomerisation domain IncA PF04156.9 CBZ53014.1 - 0.43 10.1 20.2 0.024 14.2 5.8 2.7 2 0 0 2 2 2 0 IncA protein DUF3138 PF11336.3 CBZ53014.1 - 0.83 7.7 4.7 3.4 5.7 0.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3138) APG6 PF04111.7 CBZ53014.1 - 1 8.3 21.8 0.017 14.2 1.0 3.4 3 0 0 3 3 3 0 Autophagy protein Apg6 BRCT PF00533.21 CBZ53015.1 - 0.0021 18.1 0.0 1 9.5 0.0 2.5 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain PMT PF02366.13 CBZ53016.1 - 0.14 11.4 0.0 0.2 10.9 0.0 1.2 1 0 0 1 1 1 0 Dolichyl-phosphate-mannose-protein mannosyltransferase Allantoicase PF03561.10 CBZ53018.1 - 0.046 13.1 0.0 0.094 12.1 0.0 1.4 1 0 0 1 1 1 0 Allantoicase repeat LCCL PF03815.14 CBZ53021.1 - 4.7e-15 55.3 0.1 1.3e-14 53.9 0.0 1.7 1 0 0 1 1 1 1 LCCL domain F5_F8_type_C PF00754.20 CBZ53021.1 - 1.2e-08 34.8 0.0 2.3e-08 33.9 0.0 1.4 1 0 0 1 1 1 1 F5/8 type C domain PA14 PF07691.7 CBZ53021.1 - 1.6e-08 34.3 0.0 2.2e-07 30.6 0.0 2.5 2 1 1 3 3 3 2 PA14 domain DnaJ PF00226.26 CBZ53022.1 - 2.2e-27 94.5 2.3 3.2e-27 94.0 1.6 1.2 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 CBZ53022.1 - 0.00025 21.0 2.0 0.00043 20.2 1.4 1.3 1 0 0 1 1 1 1 DnaJ central domain Elong-fact-P_C PF09285.6 CBZ53023.1 - 7.9e-14 50.7 0.1 2.1e-13 49.4 0.1 1.7 1 0 0 1 1 1 1 Elongation factor P, C-terminal EFP_N PF08207.7 CBZ53023.1 - 2.7e-08 33.5 0.1 1.8e-07 30.8 0.0 2.2 2 0 0 2 2 2 1 Elongation factor P (EF-P) KOW-like domain EFP PF01132.15 CBZ53023.1 - 4.1e-08 32.7 0.4 1e-07 31.5 0.0 1.8 2 0 0 2 2 2 1 Elongation factor P (EF-P) OB domain Pkinase PF00069.20 CBZ53024.1 - 1.4e-15 57.1 0.0 9.4e-15 54.4 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Kinase-like PF14531.1 CBZ53024.1 - 7.7e-09 34.9 0.0 1.3e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_Tyr PF07714.12 CBZ53024.1 - 0.00076 18.6 0.0 0.0012 18.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.17 CBZ53024.1 - 0.058 12.7 0.0 0.092 12.0 0.0 1.2 1 0 0 1 1 1 0 RIO1 family AflR PF08493.5 CBZ53024.1 - 0.14 11.1 0.0 0.22 10.5 0.0 1.2 1 0 0 1 1 1 0 Aflatoxin regulatory protein PIP49_C PF12260.3 CBZ53024.1 - 0.18 11.1 0.1 0.31 10.4 0.0 1.2 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 DUF607 PF04678.8 CBZ53025.1 - 0.16 11.8 0.5 0.37 10.7 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF607 SNF2_N PF00176.18 CBZ53027.1 - 1.5e-61 207.7 0.1 2.6e-61 207.0 0.1 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 CBZ53027.1 - 1e-14 54.1 0.0 2e-14 53.1 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Chromo PF00385.19 CBZ53027.1 - 1.6e-14 53.2 2.7 2.6e-08 33.4 0.0 3.1 2 1 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain DUF4208 PF13907.1 CBZ53027.1 - 1.3e-06 28.5 0.0 5.4e-06 26.5 0.0 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4208) ResIII PF04851.10 CBZ53027.1 - 4.7e-05 23.2 0.0 0.00016 21.5 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.3 CBZ53027.1 - 0.00017 20.5 0.1 0.031 13.1 0.0 2.5 1 1 1 2 2 2 2 Class II histone deacetylase complex subunits 2 and 3 DEAD PF00270.24 CBZ53027.1 - 0.00031 20.2 0.0 0.00088 18.8 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase Kinase-like PF14531.1 CBZ53028.1 - 1.3e-17 63.7 0.0 2.6e-17 62.7 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Pkinase PF00069.20 CBZ53028.1 - 2.1e-17 63.1 0.0 7.9e-17 61.2 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ53028.1 - 8.6e-07 28.2 0.0 3.7e-06 26.2 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase RIO1 PF01163.17 CBZ53028.1 - 0.049 12.9 0.0 0.082 12.2 0.0 1.2 1 0 0 1 1 1 0 RIO1 family APH PF01636.18 CBZ53028.1 - 0.054 13.2 0.6 0.22 11.2 0.0 2.1 2 0 0 2 2 2 0 Phosphotransferase enzyme family RNA_pol_Rpb2_6 PF00562.23 CBZ53029.1 - 7.5e-121 403.5 0.0 1e-120 403.0 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 CBZ53029.1 - 6.5e-60 201.5 0.0 9e-60 201.0 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.9 CBZ53029.1 - 9.9e-50 168.5 0.0 1.6e-49 167.9 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.15 CBZ53029.1 - 1.5e-30 105.3 0.1 3.2e-30 104.2 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_3 PF04565.11 CBZ53029.1 - 1.2e-24 85.8 0.0 2.4e-24 84.8 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_4 PF04566.8 CBZ53029.1 - 2.3e-22 78.5 0.1 6e-22 77.2 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_5 PF04567.12 CBZ53029.1 - 1.5e-16 60.0 3.6 5e-16 58.3 0.9 2.7 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 5 ELMO_CED12 PF04727.8 CBZ53031.1 - 1.7e-20 73.2 0.1 7.5e-20 71.1 0.1 2.0 2 0 0 2 2 2 1 ELMO/CED-12 family Carb_kinase PF01256.12 CBZ53033.1 - 6.2e-28 97.7 1.3 1.7e-15 57.0 0.0 4.2 4 0 0 4 4 4 4 Carbohydrate kinase Proteasome PF00227.21 CBZ53034.1 - 9.5e-54 181.5 0.2 1.2e-53 181.1 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 CBZ53034.1 - 7.8e-15 53.8 0.0 1.3e-14 53.1 0.0 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Ras PF00071.17 CBZ53035.1 - 2.2e-63 212.4 0.4 2.6e-63 212.2 0.3 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CBZ53035.1 - 3.3e-19 69.5 0.0 5.7e-19 68.7 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CBZ53035.1 - 4.2e-15 55.4 0.0 5.4e-15 55.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 CBZ53035.1 - 1.5e-06 27.5 0.0 1.9e-06 27.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 CBZ53035.1 - 2.1e-05 24.0 0.1 5.3e-05 22.7 0.1 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 CBZ53035.1 - 3e-05 23.9 0.0 5.1e-05 23.2 0.0 1.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 CBZ53035.1 - 0.00016 20.9 0.0 0.00021 20.5 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_22 PF13401.1 CBZ53035.1 - 0.0087 16.2 0.0 0.015 15.4 0.0 1.6 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 CBZ53035.1 - 0.02 14.1 0.0 0.039 13.1 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function, DUF258 AAA_16 PF13191.1 CBZ53035.1 - 0.054 13.4 0.0 0.12 12.3 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain AAA_5 PF07728.9 CBZ53035.1 - 0.057 13.1 0.1 0.24 11.1 0.0 2.0 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) DAP3 PF10236.4 CBZ53035.1 - 0.15 10.9 0.0 0.26 10.1 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 Pex2_Pex12 PF04757.9 CBZ53036.1 - 7.3e-24 84.4 6.0 1.1e-23 83.9 4.2 1.2 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_3 PF13920.1 CBZ53036.1 - 0.17 11.5 8.2 0.91 9.2 2.6 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Zn-ribbon_8 PF09723.5 CBZ53036.1 - 0.67 9.9 3.1 3.4 7.7 0.2 2.5 2 0 0 2 2 2 0 Zinc ribbon domain PIG-L PF02585.12 CBZ53037.1 - 1e-21 77.7 0.1 1.7e-21 77.0 0.0 1.3 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase Sdh5 PF03937.11 CBZ53038.1 - 4.9e-15 54.9 0.0 1.4e-14 53.5 0.0 1.6 1 1 1 2 2 2 1 Flavinator of succinate dehydrogenase L_biotic_typeA PF04604.8 CBZ53038.1 - 0.057 13.0 0.0 3.4 7.3 0.0 2.2 1 1 1 2 2 2 0 Type-A lantibiotic GAS PF13851.1 CBZ53040.1 - 4e-05 22.8 28.1 4e-05 22.8 19.5 7.5 5 2 3 8 8 8 2 Growth-arrest specific micro-tubule binding IncA PF04156.9 CBZ53040.1 - 0.00021 20.9 5.5 0.00021 20.9 3.8 6.9 3 1 3 6 6 6 1 IncA protein APG6 PF04111.7 CBZ53040.1 - 0.0032 16.5 19.4 0.0032 16.5 13.4 6.7 4 1 3 7 7 7 3 Autophagy protein Apg6 Actin PF00022.14 CBZ53043.1 - 3.5e-79 266.0 0.0 3.4e-78 262.8 0.0 1.9 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.8 CBZ53043.1 - 0.0068 15.0 0.0 0.04 12.5 0.0 2.0 2 0 0 2 2 2 1 MreB/Mbl protein DNA_pol_B PF00136.16 CBZ53044.1 - 2.6e-137 458.4 1.9 3.7e-137 457.9 1.3 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 CBZ53044.1 - 3.3e-51 174.1 0.0 1.8e-40 138.7 0.0 2.4 1 1 1 2 2 2 2 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.1 CBZ53044.1 - 7.5e-23 80.3 8.5 1.6e-22 79.2 5.9 1.6 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta DNA_pol_B_2 PF03175.8 CBZ53044.1 - 0.058 12.0 0.4 0.4 9.2 0.1 2.2 2 0 0 2 2 2 0 DNA polymerase type B, organellar and viral Glu_cyclase_2 PF05096.7 CBZ53045.1 - 1.4e-11 43.8 0.0 7e-06 25.2 0.0 2.6 3 0 0 3 3 3 2 Glutamine cyclotransferase Pkinase PF00069.20 CBZ53046.1 - 3.2e-60 203.4 0.0 7e-59 199.0 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ53046.1 - 2.2e-28 99.0 0.0 3.9e-28 98.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBZ53046.1 - 2.9e-06 26.4 0.0 4.6e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like YrbL-PhoP_reg PF10707.4 CBZ53046.1 - 0.079 12.2 0.0 0.16 11.3 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Pox_ser-thr_kin PF05445.6 CBZ53046.1 - 0.42 9.3 0.2 0.62 8.7 0.2 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase AAA_2 PF07724.9 CBZ53048.1 - 3.4e-52 176.7 0.0 5.3e-51 172.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA PF00004.24 CBZ53048.1 - 3.7e-26 91.8 0.0 2.7e-13 50.2 0.0 3.1 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.4 CBZ53048.1 - 2e-21 75.7 0.1 8.3e-21 73.6 0.1 2.2 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.9 CBZ53048.1 - 1.1e-16 60.8 0.1 1.7e-10 40.7 0.0 3.4 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) Clp_N PF02861.15 CBZ53048.1 - 1.5e-13 50.4 0.0 8.7e-08 31.9 0.0 3.0 2 0 0 2 2 2 2 Clp amino terminal domain AAA_16 PF13191.1 CBZ53048.1 - 9.3e-13 48.5 11.0 1.2e-05 25.3 0.0 5.6 3 3 1 4 4 4 3 AAA ATPase domain AAA_22 PF13401.1 CBZ53048.1 - 6.9e-10 39.1 0.0 0.0022 18.1 0.0 3.8 2 2 0 2 2 2 2 AAA domain Sigma54_activat PF00158.21 CBZ53048.1 - 6.3e-08 32.2 0.0 2.6e-05 23.7 0.0 2.9 2 1 0 2 2 2 1 Sigma-54 interaction domain AAA_14 PF13173.1 CBZ53048.1 - 2.6e-07 30.5 0.0 0.016 15.0 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.1 CBZ53048.1 - 9e-07 29.2 0.0 0.04 14.2 0.0 2.9 2 0 0 2 2 2 2 AAA domain Arch_ATPase PF01637.13 CBZ53048.1 - 1.6e-06 28.0 6.6 0.14 11.8 0.1 4.1 3 2 0 4 4 3 3 Archaeal ATPase AAA_17 PF13207.1 CBZ53048.1 - 1.6e-06 28.8 5.0 0.0096 16.7 0.0 3.8 3 2 0 3 3 3 2 AAA domain AAA_10 PF12846.2 CBZ53048.1 - 1.9e-05 24.2 0.5 0.026 13.9 0.0 3.8 3 1 0 4 4 4 1 AAA-like domain RuvB_N PF05496.7 CBZ53048.1 - 1.9e-05 23.8 0.6 0.018 14.1 0.0 3.2 3 1 0 3 3 3 1 Holliday junction DNA helicase ruvB N-terminus IstB_IS21 PF01695.12 CBZ53048.1 - 3.8e-05 23.1 0.0 0.063 12.6 0.0 2.6 2 0 0 2 2 2 2 IstB-like ATP binding protein NTPase_1 PF03266.10 CBZ53048.1 - 0.00013 21.7 0.1 1.9 8.1 0.0 4.2 4 0 0 4 4 4 1 NTPase RNA_helicase PF00910.17 CBZ53048.1 - 0.00014 22.0 0.0 0.94 9.6 0.0 2.8 3 0 0 3 3 2 2 RNA helicase Mg_chelatase PF01078.16 CBZ53048.1 - 0.00019 20.6 0.0 0.43 9.7 0.0 3.6 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI DUF815 PF05673.8 CBZ53048.1 - 0.00022 20.2 0.0 0.057 12.3 0.0 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF815) Zeta_toxin PF06414.7 CBZ53048.1 - 0.0003 19.9 0.0 0.023 13.8 0.0 3.3 3 0 0 3 3 3 1 Zeta toxin NACHT PF05729.7 CBZ53048.1 - 0.00037 20.1 0.0 1.1 8.9 0.0 2.8 2 0 0 2 2 2 2 NACHT domain AAA_19 PF13245.1 CBZ53048.1 - 0.00046 19.8 0.2 0.21 11.3 0.0 3.0 3 0 0 3 3 2 1 Part of AAA domain MobB PF03205.9 CBZ53048.1 - 0.00046 19.9 0.0 0.29 10.8 0.0 2.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B DUF258 PF03193.11 CBZ53048.1 - 0.0016 17.6 0.0 0.84 8.8 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_28 PF13521.1 CBZ53048.1 - 0.0032 17.4 0.2 6 6.7 0.0 3.7 3 1 1 4 4 3 0 AAA domain DNA_pol3_delta2 PF13177.1 CBZ53048.1 - 0.0033 17.1 0.0 0.024 14.3 0.0 2.4 2 1 0 2 2 1 1 DNA polymerase III, delta subunit MMR_HSR1 PF01926.18 CBZ53048.1 - 0.0046 16.9 0.0 0.3 11.0 0.0 2.8 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_33 PF13671.1 CBZ53048.1 - 0.0052 16.6 0.1 0.94 9.3 0.0 3.3 3 0 0 3 3 2 1 AAA domain AAA_3 PF07726.6 CBZ53048.1 - 0.006 16.1 0.0 0.8 9.3 0.0 3.4 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.1 CBZ53048.1 - 0.0064 15.9 0.0 0.72 9.4 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain ABC_tran PF00005.22 CBZ53048.1 - 0.007 16.6 0.1 3.8 7.8 0.0 3.2 3 0 0 3 3 2 1 ABC transporter AAA_25 PF13481.1 CBZ53048.1 - 0.007 15.7 0.5 3.6 6.9 0.0 3.8 4 0 0 4 4 4 1 AAA domain ATP_bind_1 PF03029.12 CBZ53048.1 - 0.016 14.7 0.0 1.4 8.3 0.0 3.2 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein AAA_23 PF13476.1 CBZ53048.1 - 0.035 14.4 4.3 5.3 7.3 0.0 3.4 3 0 0 3 3 3 0 AAA domain Miro PF08477.8 CBZ53048.1 - 0.043 14.3 0.0 2.9 8.4 0.0 2.9 3 0 0 3 3 2 0 Miro-like protein AAA_24 PF13479.1 CBZ53048.1 - 0.11 12.1 0.0 2.5 7.6 0.0 2.7 2 0 0 2 2 2 0 AAA domain RRF PF01765.14 CBZ53049.1 - 7.4e-25 87.3 0.9 1.1e-24 86.7 0.6 1.3 1 0 0 1 1 1 1 Ribosome recycling factor Med4 PF10018.4 CBZ53050.1 - 0.7 9.2 5.6 0.27 10.6 0.6 2.4 3 0 0 3 3 3 0 Vitamin-D-receptor interacting Mediator subunit 4 NTP_transferase PF00483.18 CBZ53051.1 - 3.7e-40 137.7 0.0 1.5e-21 76.8 0.0 2.1 2 0 0 2 2 2 2 Nucleotidyl transferase Hexapep PF00132.19 CBZ53051.1 - 4.2e-09 35.4 6.0 2.3e-06 26.8 0.2 3.3 2 1 1 3 3 3 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 CBZ53051.1 - 4e-06 26.2 1.5 4e-06 26.2 1.1 3.7 3 2 1 4 4 4 1 Hexapeptide repeat of succinyl-transferase NTP_transf_3 PF12804.2 CBZ53051.1 - 5.1e-06 26.6 0.1 1.5e-05 25.1 0.1 1.8 1 1 0 1 1 1 1 MobA-like NTP transferase domain PDEase_I PF00233.14 CBZ53052.1 - 5.7e-17 62.2 1.4 1.1e-10 41.7 0.0 2.1 2 0 0 2 2 2 2 3'5'-cyclic nucleotide phosphodiesterase PDEase_I PF00233.14 CBZ53053.1 - 1.6e-07 31.3 0.0 0.00027 20.7 0.0 2.2 2 0 0 2 2 2 2 3'5'-cyclic nucleotide phosphodiesterase DUF3625 PF12293.3 CBZ53053.1 - 0.023 13.8 0.2 0.039 13.0 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3625) DUF3292 PF11696.3 CBZ53053.1 - 0.38 8.5 0.1 0.58 7.9 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) ORC6 PF05460.8 CBZ53053.1 - 2.4 7.1 6.5 0.16 11.0 0.1 2.3 2 0 0 2 2 2 0 Origin recognition complex subunit 6 (ORC6) p47_phox_C PF08944.6 CBZ53054.1 - 0.22 11.7 5.8 9.6 6.4 0.0 3.5 4 0 0 4 4 4 0 NADPH oxidase subunit p47Phox, C terminal domain MUG2_C PF08593.5 CBZ53054.1 - 0.42 10.8 5.7 14 6.0 0.0 4.3 3 2 1 4 4 4 0 Meiotically up-regulated glycoproteins C-terminal NTP_transf_2 PF01909.18 CBZ53056.1 - 0.0029 17.8 0.0 0.0059 16.9 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyltransferase domain Hist_deacetyl PF00850.14 CBZ53057.1 - 1.5e-24 86.8 0.4 1.9e-11 43.8 0.0 3.0 3 0 0 3 3 3 2 Histone deacetylase domain SET PF00856.23 CBZ53059.1 - 1.3e-25 90.5 0.1 1.7e-24 86.9 0.1 3.1 1 1 0 1 1 1 1 SET domain PHD PF00628.24 CBZ53059.1 - 0.00042 19.9 24.7 0.0011 18.6 6.5 5.2 6 0 0 6 6 6 3 PHD-finger S-methyl_trans PF02574.11 CBZ53061.1 - 1.7e-43 149.0 0.0 2.3e-16 59.9 0.0 3.3 3 1 0 3 3 3 3 Homocysteine S-methyltransferase ADK PF00406.17 CBZ53062.1 - 3e-38 131.0 0.0 1.4e-25 89.8 0.0 2.2 1 1 1 2 2 2 2 Adenylate kinase AAA_18 PF13238.1 CBZ53062.1 - 1.6e-08 34.9 0.1 6.6e-07 29.6 0.1 2.5 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 CBZ53062.1 - 3.5e-07 30.1 0.0 5e-05 23.2 0.0 2.3 1 1 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.12 CBZ53062.1 - 1.5e-05 24.4 0.4 0.031 13.6 0.1 2.3 2 0 0 2 2 2 2 Thymidylate kinase AAA_17 PF13207.1 CBZ53062.1 - 6.3e-05 23.7 0.2 0.00018 22.3 0.1 2.0 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 CBZ53062.1 - 0.00047 19.3 0.1 0.0018 17.4 0.0 2.0 2 0 0 2 2 2 1 Zeta toxin AAA_28 PF13521.1 CBZ53062.1 - 0.047 13.6 0.3 1 9.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain Peptidase_M24 PF00557.19 CBZ53063.1 - 1.5e-42 145.5 0.1 1.8e-42 145.2 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 E1-E2_ATPase PF00122.15 CBZ53064.1 - 1.2e-13 50.6 0.4 2.5e-10 39.7 0.0 2.7 2 0 0 2 2 2 2 E1-E2 ATPase Hydrolase PF00702.21 CBZ53064.1 - 8e-08 32.9 0.1 0.1 13.0 0.0 3.4 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase HAD PF12710.2 CBZ53064.1 - 2.7e-06 27.7 0.0 0.54 10.3 0.0 3.4 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 CBZ53064.1 - 3.1e-05 23.8 0.0 9.3e-05 22.3 0.0 1.8 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 CBZ53064.1 - 0.13 11.8 0.0 0.39 10.2 0.0 1.7 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Dispanin PF04505.7 CBZ53066.1 - 0.008 15.7 0.1 0.015 14.8 0.1 1.4 1 0 0 1 1 1 1 Interferon-induced transmembrane protein HEAT PF02985.17 CBZ53067.1 - 1.6e-05 24.6 15.2 1.3 9.2 0.1 5.5 5 0 0 5 5 5 3 HEAT repeat OPA3 PF07047.7 CBZ53067.1 - 0.0028 17.4 0.0 2.7 7.7 0.0 2.5 2 0 0 2 2 2 2 Optic atrophy 3 protein (OPA3) Condensin2nSMC PF12422.3 CBZ53067.1 - 0.0039 16.9 0.0 0.01 15.5 0.0 1.6 1 0 0 1 1 1 1 Condensin II non structural maintenance of chromosomes subunit M11L PF11099.3 CBZ53067.1 - 0.31 10.7 0.1 1.4 8.6 0.0 1.8 2 0 0 2 2 2 0 Apoptosis regulator M11L like Adaptin_N PF01602.15 CBZ53067.1 - 1.2 7.3 0.8 16 3.6 0.0 2.5 3 0 0 3 3 3 0 Adaptin N terminal region TFIIA PF03153.8 CBZ53068.1 - 0.096 12.5 12.0 0.11 12.3 8.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SprA-related PF12118.3 CBZ53068.1 - 0.14 11.4 19.2 0.18 11.1 13.3 1.1 1 0 0 1 1 1 0 SprA-related family Peptidase_S64 PF08192.6 CBZ53068.1 - 0.32 9.2 15.5 0.41 8.9 10.7 1.0 1 0 0 1 1 1 0 Peptidase family S64 Macoilin PF09726.4 CBZ53068.1 - 0.55 8.4 15.2 0.7 8.1 10.6 1.0 1 0 0 1 1 1 0 Transmembrane protein Patatin PF01734.17 CBZ53068.1 - 1.1 9.2 12.9 5.5 6.8 8.9 1.9 1 1 0 1 1 1 0 Patatin-like phospholipase Mitofilin PF09731.4 CBZ53068.1 - 1.2 7.7 7.2 1.4 7.4 5.0 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Rifin_STEVOR PF02009.11 CBZ53068.1 - 1.6 8.3 10.5 1.8 8.1 6.9 1.5 2 0 0 2 2 2 0 Rifin/stevor family DUF966 PF06136.8 CBZ53068.1 - 2.3 7.5 12.4 2.8 7.2 8.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF966) IER PF05760.7 CBZ53068.1 - 2.6 7.8 10.6 3.1 7.6 7.3 1.2 1 0 0 1 1 1 0 Immediate early response protein (IER) Plasmodium_Vir PF05795.6 CBZ53068.1 - 3.2 6.8 7.8 4 6.5 5.4 1.3 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Atg14 PF10186.4 CBZ53070.1 - 4.7 6.0 7.0 6.6 5.5 4.8 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 ABC_ATPase PF09818.4 CBZ53071.1 - 5.8e-132 440.4 0.0 2e-107 359.6 0.0 2.0 1 1 1 2 2 2 2 Predicted ATPase of the ABC class AAA_23 PF13476.1 CBZ53071.1 - 0.00023 21.5 0.0 0.00038 20.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.1 CBZ53071.1 - 0.073 12.6 0.0 0.17 11.4 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_25 PF13481.1 CBZ53071.1 - 0.14 11.5 0.1 0.27 10.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain TPR_11 PF13414.1 CBZ53072.1 - 7.7e-20 70.3 36.1 0.00021 20.8 0.0 10.2 10 2 2 12 12 12 5 TPR repeat TPR_17 PF13431.1 CBZ53072.1 - 1.4e-08 34.2 10.9 12 6.3 0.0 10.5 11 0 0 11 11 10 1 Tetratricopeptide repeat TPR_14 PF13428.1 CBZ53072.1 - 2.7e-06 27.4 54.4 0.02 15.5 0.4 11.1 11 0 0 11 11 10 3 Tetratricopeptide repeat TPR_16 PF13432.1 CBZ53072.1 - 6.5e-06 26.6 56.7 0.015 16.0 0.7 10.6 8 3 3 12 12 11 5 Tetratricopeptide repeat TPR_8 PF13181.1 CBZ53072.1 - 2e-05 24.0 4.6 2.4 8.1 0.0 6.4 6 1 1 7 7 6 2 Tetratricopeptide repeat TPR_1 PF00515.23 CBZ53072.1 - 2.1e-05 23.9 13.5 0.0052 16.3 0.0 7.0 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_19 PF14559.1 CBZ53072.1 - 4.2e-05 23.8 56.2 0.074 13.4 0.1 12.1 12 1 1 13 13 12 3 Tetratricopeptide repeat Apc3 PF12895.2 CBZ53072.1 - 0.00031 20.8 24.1 0.5 10.5 0.0 8.0 8 1 0 8 8 8 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.12 CBZ53072.1 - 0.0013 18.5 0.0 0.0013 18.5 0.0 9.4 10 0 0 10 10 10 1 Tetratricopeptide repeat TPR_6 PF13174.1 CBZ53072.1 - 0.0028 18.0 18.0 0.23 11.9 0.0 8.1 9 0 0 9 9 6 2 Tetratricopeptide repeat TPR_12 PF13424.1 CBZ53072.1 - 1.4 8.8 48.1 0.52 10.2 0.1 10.7 11 2 2 13 13 12 0 Tetratricopeptide repeat Thr_dehydrat_C PF00585.13 CBZ53074.1 - 0.05 13.1 0.0 0.15 11.6 0.0 1.8 1 0 0 1 1 1 0 C-terminal regulatory domain of Threonine dehydratase Pep3_Vps18 PF05131.9 CBZ53074.1 - 0.078 12.4 0.0 0.5 9.7 0.0 2.0 2 0 0 2 2 2 0 Pep3/Vps18/deep orange family Ycf1 PF05758.7 CBZ53076.1 - 3.1 5.3 0.1 5.8 4.4 0.1 1.3 1 0 0 1 1 1 0 Ycf1 GTP_EFTU PF00009.22 CBZ53077.1 - 5.5e-08 32.4 0.0 0.0001 21.8 0.0 2.6 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 CBZ53077.1 - 0.051 13.5 0.0 7.3 6.5 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase Miro PF08477.8 CBZ53077.1 - 0.21 12.1 0.0 0.65 10.5 0.0 1.9 1 0 0 1 1 1 0 Miro-like protein UNC-50 PF05216.8 CBZ53078.1 - 1.1e-35 122.9 9.8 1.4e-35 122.6 6.8 1.1 1 0 0 1 1 1 1 UNC-50 family IncA PF04156.9 CBZ53078.1 - 8.8 5.8 6.5 0.61 9.6 0.7 1.8 2 0 0 2 2 2 0 IncA protein AMA-1 PF02430.10 CBZ53079.1 - 8.6e-54 183.1 3.2 5e-47 160.8 0.9 2.4 2 1 0 2 2 2 2 Apical membrane antigen 1 DUF2881 PF11087.3 CBZ53079.1 - 8.1 6.0 6.6 0.42 10.1 0.7 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2881) Nol1_Nop2_Fmu PF01189.12 CBZ53080.1 - 7.4e-27 94.4 0.0 3.4e-17 62.7 0.0 4.0 4 0 0 4 4 4 3 NOL1/NOP2/sun family FtsJ PF01728.14 CBZ53080.1 - 0.039 13.9 0.0 0.15 11.9 0.0 1.9 2 1 0 2 2 2 0 FtsJ-like methyltransferase Tom22 PF04281.8 CBZ53081.1 - 3.2e-05 23.4 0.2 3.8e-05 23.2 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom22 CD20 PF04103.10 CBZ53081.1 - 0.06 13.2 0.1 0.067 13.1 0.0 1.1 1 0 0 1 1 1 0 CD20-like family Cnd1 PF12717.2 CBZ53082.1 - 4.9e-38 130.7 0.0 1e-34 119.9 0.0 2.8 2 0 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.17 CBZ53082.1 - 0.001 18.9 8.7 5.8 7.2 0.0 6.2 5 0 0 5 5 5 1 HEAT repeat Cohesin_HEAT PF12765.2 CBZ53082.1 - 0.054 13.4 0.9 0.35 10.8 0.1 2.7 2 0 0 2 2 2 0 HEAT repeat associated with sister chromatid cohesion Nipped-B_C PF12830.2 CBZ53082.1 - 0.31 10.6 0.0 0.97 9.0 0.0 1.8 1 0 0 1 1 1 0 Sister chromatid cohesion C-terminus Adaptin_N PF01602.15 CBZ53082.1 - 1.1 7.4 0.1 27 2.8 0.0 2.2 2 0 0 2 2 2 0 Adaptin N terminal region ACDC PF14733.1 CBZ53083.1 - 4.2e-23 81.2 0.1 8.4e-23 80.3 0.1 1.5 1 0 0 1 1 1 1 AP2-coincident C-terminal AP2 PF00847.15 CBZ53083.1 - 8.1e-14 51.5 10.0 9.1e-09 35.3 0.1 3.5 3 1 0 3 3 3 2 AP2 domain Pol_alpha_B_N PF08418.5 CBZ53083.1 - 4.3 6.7 6.7 25 4.2 4.6 2.4 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal AAA PF00004.24 CBZ53084.1 - 5.5e-51 172.2 0.0 1.6e-43 148.0 0.0 2.9 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 CBZ53084.1 - 4.9e-11 43.4 0.0 0.00013 22.7 0.0 2.6 2 1 0 2 2 2 2 AAA domain AAA_22 PF13401.1 CBZ53084.1 - 5.4e-10 39.5 0.6 0.0005 20.2 0.1 3.3 2 1 0 2 2 2 2 AAA domain RuvB_N PF05496.7 CBZ53084.1 - 7.2e-09 35.0 0.0 1.3e-05 24.3 0.0 2.5 2 0 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 CBZ53084.1 - 7.7e-08 32.1 0.7 0.017 14.8 0.0 3.1 3 1 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 CBZ53084.1 - 2.6e-07 30.6 0.0 0.0042 16.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 CBZ53084.1 - 3.4e-07 30.4 4.1 0.028 14.3 0.1 3.2 2 1 1 3 3 3 2 AAA ATPase domain AAA_14 PF13173.1 CBZ53084.1 - 1.1e-06 28.5 0.0 0.05 13.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.1 CBZ53084.1 - 4.9e-06 26.8 0.0 0.006 16.8 0.0 2.4 2 0 0 2 2 2 2 AAA domain TIP49 PF06068.8 CBZ53084.1 - 9.1e-06 24.6 0.2 0.0017 17.1 0.0 2.3 2 0 0 2 2 2 1 TIP49 C-terminus AAA_19 PF13245.1 CBZ53084.1 - 4.5e-05 23.1 2.6 0.0086 15.8 0.1 3.7 3 1 0 3 3 3 1 Part of AAA domain IstB_IS21 PF01695.12 CBZ53084.1 - 5.4e-05 22.6 0.1 0.0011 18.3 0.0 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein RNA_helicase PF00910.17 CBZ53084.1 - 6.7e-05 23.0 0.0 0.13 12.4 0.0 2.4 2 0 0 2 2 2 2 RNA helicase Mg_chelatase PF01078.16 CBZ53084.1 - 6.8e-05 22.1 1.0 0.025 13.7 0.1 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_25 PF13481.1 CBZ53084.1 - 0.00018 20.9 0.1 0.0011 18.4 0.0 2.2 2 1 0 2 2 1 1 AAA domain DUF815 PF05673.8 CBZ53084.1 - 0.00037 19.4 0.0 0.08 11.8 0.0 2.6 2 1 0 2 2 2 1 Protein of unknown function (DUF815) AAA_28 PF13521.1 CBZ53084.1 - 0.00039 20.4 0.1 0.012 15.5 0.0 2.7 3 0 0 3 3 2 1 AAA domain SKI PF01202.17 CBZ53084.1 - 0.00049 19.9 0.1 0.97 9.2 0.0 2.4 2 0 0 2 2 2 2 Shikimate kinase Sigma54_activ_2 PF14532.1 CBZ53084.1 - 0.00073 19.5 0.0 0.6 10.1 0.0 2.7 2 0 0 2 2 2 1 Sigma-54 interaction domain UPF0079 PF02367.12 CBZ53084.1 - 0.00078 19.0 0.2 0.21 11.2 0.0 2.5 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 Arch_ATPase PF01637.13 CBZ53084.1 - 0.00096 18.9 0.0 0.52 9.9 0.0 2.9 2 1 1 3 3 3 1 Archaeal ATPase Zeta_toxin PF06414.7 CBZ53084.1 - 0.0017 17.4 0.1 0.033 13.2 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin NACHT PF05729.7 CBZ53084.1 - 0.0018 17.9 0.8 2.3 7.8 0.1 3.1 3 0 0 3 3 3 1 NACHT domain Sigma54_activat PF00158.21 CBZ53084.1 - 0.0019 17.6 0.1 1.6 8.1 0.0 2.8 3 0 0 3 3 3 1 Sigma-54 interaction domain AAA_2 PF07724.9 CBZ53084.1 - 0.002 18.0 0.0 0.087 12.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) ABC_tran PF00005.22 CBZ53084.1 - 0.0035 17.6 0.0 0.41 10.9 0.0 2.5 2 0 0 2 2 2 1 ABC transporter Rad17 PF03215.10 CBZ53084.1 - 0.0037 16.0 0.0 1.5 7.3 0.0 2.1 2 0 0 2 2 2 2 Rad17 cell cycle checkpoint protein NTPase_1 PF03266.10 CBZ53084.1 - 0.0046 16.6 0.2 1.6 8.4 0.0 2.4 2 0 0 2 2 2 1 NTPase AAA_3 PF07726.6 CBZ53084.1 - 0.0068 16.0 0.0 0.21 11.2 0.0 3.0 3 1 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) PhoH PF02562.11 CBZ53084.1 - 0.0076 15.4 0.1 0.054 12.7 0.0 2.3 2 0 0 2 2 2 1 PhoH-like protein KaiC PF06745.8 CBZ53084.1 - 0.026 13.6 0.1 0.15 11.1 0.0 2.1 2 0 0 2 2 2 0 KaiC NB-ARC PF00931.17 CBZ53084.1 - 0.027 13.3 0.1 2.3 7.0 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain T2SE PF00437.15 CBZ53084.1 - 0.031 13.1 0.0 0.57 9.0 0.0 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein Cytidylate_kin2 PF13189.1 CBZ53084.1 - 0.034 14.0 0.0 2.7 7.8 0.0 2.3 2 0 0 2 2 2 0 Cytidylate kinase-like family Parvo_NS1 PF01057.12 CBZ53084.1 - 0.1 11.4 0.0 0.18 10.6 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_11 PF13086.1 CBZ53084.1 - 0.11 12.0 0.0 0.87 9.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.1 CBZ53084.1 - 0.11 12.0 0.6 0.51 9.8 0.1 2.0 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.1 CBZ53084.1 - 0.12 11.9 1.1 4.6 6.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain ATP-synt_ab PF00006.20 CBZ53084.1 - 0.16 11.4 0.0 2.7 7.4 0.0 2.2 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain DUF2075 PF09848.4 CBZ53084.1 - 0.24 10.3 0.0 0.38 9.6 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) VitK2_biosynth PF02621.9 CBZ53085.1 - 0.065 12.4 0.0 0.098 11.8 0.0 1.2 1 0 0 1 1 1 0 Menaquinone biosynthesis Radial_spoke PF04712.7 CBZ53085.1 - 0.14 10.9 0.0 0.21 10.2 0.0 1.3 1 0 0 1 1 1 0 Radial spokehead-like protein Myosin_head PF00063.16 CBZ53086.1 - 1e-164 549.3 0.0 3.8e-133 444.9 0.0 2.2 2 0 0 2 2 2 2 Myosin head (motor domain) Dynein_light PF01221.13 CBZ53086.1 - 0.00032 20.6 0.0 0.0012 18.7 0.0 1.9 2 0 0 2 2 2 1 Dynein light chain type 1 AAA_22 PF13401.1 CBZ53086.1 - 0.013 15.6 0.1 0.083 13.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 CBZ53086.1 - 0.025 13.6 0.0 0.047 12.7 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_30 PF13604.1 CBZ53086.1 - 0.068 12.7 0.0 1.7 8.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 CBZ53086.1 - 0.12 11.8 0.1 0.38 10.1 0.0 1.9 2 0 0 2 2 2 0 AAA-like domain T2SE PF00437.15 CBZ53086.1 - 0.14 10.9 0.1 0.26 10.1 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein UCH PF00443.24 CBZ53087.1 - 9.6e-27 93.7 0.0 6.4e-26 91.0 0.0 2.3 3 0 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CBZ53087.1 - 2e-07 30.7 2.1 0.0098 15.3 0.0 3.6 3 1 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.7 CBZ53087.1 - 0.0013 19.0 0.0 0.014 15.8 0.0 2.4 2 0 0 2 2 2 1 DUSP domain Syndecan PF01034.15 CBZ53089.1 - 3.8 7.2 0.0 3.8 7.2 0.0 3.2 4 0 0 4 4 4 0 Syndecan domain Ebola_NP PF05505.7 CBZ53091.1 - 7.6 4.4 6.2 13 3.7 4.3 1.2 1 0 0 1 1 1 0 Ebola nucleoprotein zf-CCCH PF00642.19 CBZ53092.1 - 0.0054 16.3 9.1 0.0093 15.6 4.5 2.3 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Kelch_3 PF13415.1 CBZ53093.1 - 5.9e-31 105.9 12.7 1.1e-07 31.8 0.1 6.5 6 1 0 6 6 6 5 Galactose oxidase, central domain Kelch_4 PF13418.1 CBZ53093.1 - 2.3e-30 104.1 17.1 2e-07 30.6 0.0 6.2 5 1 1 6 6 6 5 Galactose oxidase, central domain Kelch_5 PF13854.1 CBZ53093.1 - 5.3e-22 77.3 0.6 5.3e-06 26.2 0.0 6.1 6 0 0 6 6 6 4 Kelch motif Kelch_6 PF13964.1 CBZ53093.1 - 1.2e-21 75.8 15.1 0.00062 19.8 0.0 6.5 5 2 2 7 7 6 5 Kelch motif Kelch_1 PF01344.20 CBZ53093.1 - 4.2e-20 71.0 11.8 0.00089 18.7 0.3 6.7 6 1 0 6 6 6 5 Kelch motif Kelch_2 PF07646.10 CBZ53093.1 - 1.7e-08 33.9 9.9 0.31 10.8 0.1 6.8 6 1 0 6 6 6 3 Kelch motif Laminin_II PF06009.7 CBZ53093.1 - 8.1e-05 22.4 4.5 0.00018 21.2 3.1 1.6 1 0 0 1 1 1 1 Laminin Domain II TMF_DNA_bd PF12329.3 CBZ53093.1 - 0.0007 19.3 0.3 0.0007 19.3 0.2 2.2 2 1 0 2 2 2 1 TATA element modulatory factor 1 DNA binding COG6 PF06419.6 CBZ53093.1 - 0.0013 17.0 4.4 0.0018 16.5 3.0 1.2 1 0 0 1 1 1 1 Conserved oligomeric complex COG6 Reo_sigmaC PF04582.7 CBZ53093.1 - 0.0069 15.5 2.6 0.01 15.0 1.8 1.1 1 0 0 1 1 1 1 Reovirus sigma C capsid protein MCPsignal PF00015.16 CBZ53093.1 - 0.0095 15.5 2.7 0.017 14.6 1.9 1.3 1 0 0 1 1 1 1 Methyl-accepting chemotaxis protein (MCP) signalling domain Laminin_I PF06008.9 CBZ53093.1 - 0.019 14.3 1.7 0.5 9.6 0.9 2.1 1 1 1 2 2 2 0 Laminin Domain I Nup54 PF13874.1 CBZ53093.1 - 0.029 14.0 0.9 0.054 13.1 0.7 1.4 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 DUF1664 PF07889.7 CBZ53093.1 - 0.14 11.9 5.2 0.047 13.4 1.7 1.6 2 0 0 2 2 1 0 Protein of unknown function (DUF1664) APG6 PF04111.7 CBZ53093.1 - 0.2 10.6 2.5 0.35 9.8 1.7 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 IncA PF04156.9 CBZ53093.1 - 0.22 11.1 7.3 0.78 9.3 4.3 1.8 1 1 1 2 2 2 0 IncA protein NPV_P10 PF05531.7 CBZ53093.1 - 0.24 11.6 2.0 4.7 7.5 0.2 2.7 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein V_ATPase_I PF01496.14 CBZ53093.1 - 0.38 8.5 5.3 0.54 8.0 3.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Syntaxin-6_N PF09177.6 CBZ53093.1 - 1.7 9.0 5.3 4.7 7.6 0.8 2.8 2 1 1 3 3 2 0 Syntaxin 6, N-terminal Prefoldin PF02996.12 CBZ53093.1 - 1.9 8.1 6.3 19 4.9 0.1 3.2 1 1 1 3 3 3 0 Prefoldin subunit Tropomyosin_1 PF12718.2 CBZ53093.1 - 3.3 7.5 11.5 0.032 14.1 2.4 1.7 2 0 0 2 2 1 0 Tropomyosin like COG2 PF06148.6 CBZ53093.1 - 4.7 7.0 7.2 3.3 7.5 0.5 2.4 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 PGI PF00342.14 CBZ53094.1 - 6.6e-184 611.8 0.0 8e-184 611.5 0.0 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase Pkinase PF00069.20 CBZ53095.1 - 3.4e-32 111.6 0.0 4.6e-31 107.8 0.0 2.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ53095.1 - 1.4e-13 50.5 0.0 2.1e-13 49.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBZ53095.1 - 0.052 12.5 0.0 0.33 9.8 0.0 1.9 2 0 0 2 2 2 0 Kinase-like GCV_T PF01571.16 CBZ53096.1 - 6.2e-22 77.9 0.0 3.6e-16 59.1 0.0 2.6 2 0 0 2 2 2 2 Aminomethyltransferase folate-binding domain Raffinose_syn PF05691.7 CBZ53096.1 - 4.6e-10 37.6 0.2 1.8e-08 32.4 0.0 2.1 2 0 0 2 2 2 2 Raffinose synthase or seed imbibition protein Sip1 Pyrophosphatase PF00719.14 CBZ53097.1 - 6.6e-24 84.1 0.0 1.1e-17 63.9 0.0 2.4 2 0 0 2 2 2 2 Inorganic pyrophosphatase GATA PF00320.22 CBZ53098.1 - 5.7e-06 25.5 3.9 2.1e-05 23.7 2.7 2.0 1 0 0 1 1 1 1 GATA zinc finger Pro_isomerase PF00160.16 CBZ53099.1 - 7e-46 156.2 0.5 1.5e-45 155.2 0.3 1.6 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD FKBP_C PF00254.23 CBZ53099.1 - 7e-30 102.9 0.0 1.7e-29 101.7 0.0 1.7 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase TPR_11 PF13414.1 CBZ53099.1 - 6.6e-20 70.5 2.6 2.6e-12 46.1 0.0 2.3 2 0 0 2 2 2 2 TPR repeat TPR_1 PF00515.23 CBZ53099.1 - 3.6e-17 61.1 3.0 4.1e-06 26.1 0.0 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 CBZ53099.1 - 6.5e-15 53.7 3.7 0.0019 17.9 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.1 CBZ53099.1 - 9.2e-11 42.1 7.3 2.4e-06 28.0 0.8 2.5 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.1 CBZ53099.1 - 2.8e-06 26.6 0.1 0.24 11.2 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 CBZ53099.1 - 4.4e-06 26.5 2.6 5.4e-05 23.0 1.1 2.7 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 CBZ53099.1 - 5.2e-06 26.6 0.4 0.078 13.6 0.0 3.4 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 CBZ53099.1 - 1.4e-05 24.4 1.0 0.0076 15.9 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.1 CBZ53099.1 - 0.00018 21.4 0.0 0.2 11.9 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 CBZ53099.1 - 0.00045 20.5 1.8 0.036 14.3 0.5 2.7 1 1 0 2 2 2 1 Tetratricopeptide repeat MIT PF04212.13 CBZ53099.1 - 0.00065 19.5 5.4 0.0081 16.0 0.8 2.6 1 1 1 2 2 2 1 MIT (microtubule interacting and transport) domain Fis1_TPR_C PF14853.1 CBZ53099.1 - 0.03 14.1 0.0 0.096 12.5 0.0 1.8 1 0 0 1 1 1 0 Fis1 C-terminal tetratricopeptide repeat Apc3 PF12895.2 CBZ53099.1 - 0.067 13.3 0.9 0.2 11.8 0.7 1.7 1 1 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 CBZ53099.1 - 0.13 12.1 1.1 0.62 9.9 0.0 2.3 2 1 1 3 3 2 0 Tetratricopeptide repeat TPR_6 PF13174.1 CBZ53099.1 - 0.18 12.3 0.5 17 6.1 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat LRR_4 PF12799.2 CBZ53100.1 - 1.8e-13 49.7 7.2 5.8e-06 25.8 0.0 4.3 3 1 1 4 4 4 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CBZ53100.1 - 5.1e-09 35.7 7.4 3.7e-05 23.4 0.1 3.2 2 1 1 3 3 3 3 Leucine rich repeat LRR_1 PF00560.28 CBZ53100.1 - 7.7e-06 25.2 10.0 2.5 8.4 0.0 6.2 6 0 0 6 6 6 3 Leucine Rich Repeat LRR_6 PF13516.1 CBZ53100.1 - 2.2e-05 24.0 0.6 0.47 10.6 0.0 4.7 5 0 0 5 5 5 1 Leucine Rich repeat LRR_9 PF14580.1 CBZ53100.1 - 0.021 14.4 1.0 0.053 13.0 0.5 1.7 1 1 1 2 2 2 0 Leucine-rich repeat LRR_7 PF13504.1 CBZ53100.1 - 0.038 14.1 9.4 38 5.1 0.1 5.8 6 0 0 6 6 6 0 Leucine rich repeat RRM_1 PF00076.17 CBZ53101.1 - 4.9e-17 61.3 0.4 3e-16 58.7 0.0 2.4 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBZ53101.1 - 3.3e-13 49.4 0.0 2.6e-11 43.3 0.0 2.8 2 1 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBZ53101.1 - 1.3e-06 28.1 0.0 7e-05 22.5 0.0 2.4 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Cupin_8 PF13621.1 CBZ53102.1 - 1.3e-23 83.7 0.0 2.2e-23 83.0 0.0 1.3 1 0 0 1 1 1 1 Cupin-like domain JmjC PF02373.17 CBZ53102.1 - 4.7e-10 39.7 1.0 0.0011 19.2 0.0 2.3 2 0 0 2 2 2 2 JmjC domain, hydroxylase Cupin_4 PF08007.7 CBZ53102.1 - 0.031 13.5 0.0 0.069 12.3 0.0 1.5 1 0 0 1 1 1 0 Cupin superfamily protein Cupin_1 PF00190.17 CBZ53102.1 - 0.045 13.1 0.0 0.076 12.4 0.0 1.3 1 0 0 1 1 1 0 Cupin Cupin_2 PF07883.6 CBZ53102.1 - 0.073 12.5 0.0 0.2 11.2 0.0 1.6 2 0 0 2 2 2 0 Cupin domain GPI PF06560.6 CBZ53102.1 - 0.26 10.2 0.1 0.45 9.5 0.0 1.2 1 0 0 1 1 1 0 Glucose-6-phosphate isomerase (GPI) AAA PF00004.24 CBZ53103.1 - 3.6e-12 46.6 0.0 2.4e-07 31.0 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 CBZ53103.1 - 1.8e-06 28.1 0.0 0.037 14.1 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 CBZ53103.1 - 2.6e-05 24.3 0.4 8.7e-05 22.5 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_30 PF13604.1 CBZ53103.1 - 0.0023 17.5 0.0 0.017 14.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 CBZ53103.1 - 0.061 13.0 0.5 0.26 11.0 0.1 2.2 2 0 0 2 2 2 0 Part of AAA domain 5_3_exonuc_N PF02739.11 CBZ53104.1 - 6.1e-33 113.5 0.0 5.2e-30 104.0 0.0 2.2 2 0 0 2 2 2 2 5'-3' exonuclease, N-terminal resolvase-like domain 5_3_exonuc PF01367.15 CBZ53104.1 - 9.1e-10 38.6 0.0 1.9e-09 37.6 0.0 1.6 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold Helicase_C PF00271.26 CBZ53106.1 - 9.5e-14 51.0 0.0 3e-13 49.4 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain RRM_1 PF00076.17 CBZ53106.1 - 1.3e-13 50.3 0.0 2.8e-13 49.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBZ53106.1 - 7.3e-13 48.3 0.0 1.9e-12 46.9 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) OB_NTP_bind PF07717.11 CBZ53106.1 - 1.7e-12 47.1 0.0 4.6e-12 45.7 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 CBZ53106.1 - 7e-12 45.2 0.0 2.8e-11 43.3 0.0 2.1 1 0 0 1 1 1 1 Helicase associated domain (HA2) DEAD PF00270.24 CBZ53106.1 - 1.2e-07 31.4 0.0 2.2e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 CBZ53106.1 - 0.0039 17.3 0.0 0.02 15.0 0.0 2.2 1 0 0 1 1 1 1 AAA domain DND1_DSRM PF14709.1 CBZ53106.1 - 0.03 14.6 0.2 0.077 13.2 0.1 1.7 1 0 0 1 1 1 0 double strand RNA binding domain from DEAD END PROTEIN 1 NACHT PF05729.7 CBZ53106.1 - 0.046 13.3 0.7 0.17 11.4 0.5 2.1 1 1 0 1 1 1 0 NACHT domain RRM_5 PF13893.1 CBZ53106.1 - 0.1 12.4 0.0 0.2 11.5 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) T2SE PF00437.15 CBZ53106.1 - 0.11 11.4 0.0 0.21 10.4 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein SET PF00856.23 CBZ53107.1 - 1.6e-07 31.7 1.4 0.0011 19.3 0.0 3.1 2 1 1 3 3 3 2 SET domain zf-DHHC PF01529.15 CBZ53108.1 - 1.3e-13 50.7 1.3 9.3e-08 31.6 0.5 3.2 3 0 0 3 3 3 2 DHHC palmitoyltransferase CPSase_L_D2 PF02786.12 CBZ53110.1 - 9.8e-72 240.6 1.1 1.9e-71 239.7 0.8 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PYC_OADA PF02436.13 CBZ53110.1 - 1.4e-63 213.8 0.0 2.2e-63 213.2 0.0 1.3 1 0 0 1 1 1 1 Conserved carboxylase domain CPSase_L_chain PF00289.17 CBZ53110.1 - 2.5e-36 124.1 0.2 7.8e-36 122.5 0.0 2.0 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 CBZ53110.1 - 1.6e-33 114.8 0.0 2e-32 111.3 0.0 2.5 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain HMGL-like PF00682.14 CBZ53110.1 - 2.4e-28 99.4 0.0 5.1e-28 98.3 0.0 1.6 1 0 0 1 1 1 1 HMGL-like Biotin_lipoyl PF00364.17 CBZ53110.1 - 4.5e-18 64.6 2.1 1e-17 63.5 1.1 1.9 2 0 0 2 2 2 1 Biotin-requiring enzyme ATP-grasp_4 PF13535.1 CBZ53110.1 - 9.3e-18 64.6 1.2 2.8e-17 63.0 0.9 1.7 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 CBZ53110.1 - 1.9e-16 59.7 0.1 7.7e-16 57.7 0.1 1.9 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon Biotin_lipoyl_2 PF13533.1 CBZ53110.1 - 4.6e-11 42.2 2.8 1.9e-05 24.2 0.3 2.5 1 1 1 2 2 2 2 Biotin-lipoyl like Dala_Dala_lig_C PF07478.8 CBZ53110.1 - 4.1e-09 36.1 0.0 8e-09 35.1 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 CBZ53110.1 - 2.5e-08 33.4 0.5 5.4e-08 32.3 0.2 1.6 2 0 0 2 2 2 1 ATP-grasp domain HlyD PF00529.15 CBZ53110.1 - 2.4e-05 23.7 2.1 0.0011 18.4 0.2 2.3 1 1 1 2 2 2 1 HlyD family secretion protein HlyD_3 PF13437.1 CBZ53110.1 - 5.3e-05 23.5 1.0 0.69 10.2 0.1 3.4 3 0 0 3 3 2 2 HlyD family secretion protein HlyD_2 PF12700.2 CBZ53110.1 - 0.00026 20.2 0.1 0.3 10.2 0.0 2.2 1 1 1 2 2 2 2 HlyD family secretion protein ATP-grasp_3 PF02655.9 CBZ53110.1 - 0.00073 19.4 0.0 0.0015 18.4 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.6 CBZ53110.1 - 0.0088 15.5 0.9 3.7 6.9 0.0 2.9 3 0 0 3 3 3 2 RimK-like ATP-grasp domain TPR_11 PF13414.1 CBZ53111.1 - 2.4e-09 36.6 0.4 3.8e-07 29.6 0.1 2.9 1 1 1 2 2 2 2 TPR repeat GCR1_C PF12550.3 CBZ53111.1 - 0.38 10.6 0.0 0.9 9.4 0.0 1.5 1 0 0 1 1 1 0 Transcriptional activator of glycolytic enzymes TPR_2 PF07719.12 CBZ53111.1 - 1.9 8.5 6.4 1.3 9.0 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat GDPD PF03009.12 CBZ53112.1 - 1.9e-27 96.4 0.0 7.4e-21 74.7 0.0 2.1 2 0 0 2 2 2 2 Glycerophosphoryl diester phosphodiesterase family PI-PLC-X PF00388.14 CBZ53112.1 - 0.0068 15.8 0.0 0.011 15.1 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain Glycos_transf_2 PF00535.21 CBZ53113.1 - 4e-23 81.9 0.0 6.1e-23 81.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 CBZ53113.1 - 4.4e-10 39.7 0.1 1.7e-09 37.8 0.1 1.8 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.4 CBZ53113.1 - 5.6e-08 32.2 0.0 1.2e-07 31.1 0.0 1.5 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_7C PF02709.9 CBZ53113.1 - 1.2e-05 24.6 0.0 2.3e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase GlcNAc PF11397.3 CBZ53113.1 - 0.023 13.7 0.0 0.4 9.7 0.0 2.5 2 1 0 2 2 2 0 Glycosyltransferase (GlcNAc) Pkinase PF00069.20 CBZ53114.1 - 6.7e-49 166.3 0.0 1.3e-42 145.7 0.0 3.8 4 0 0 4 4 4 3 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ53114.1 - 1.7e-18 66.6 0.0 1.3e-15 57.1 0.0 3.1 3 0 0 3 3 3 2 Protein tyrosine kinase Kinase-like PF14531.1 CBZ53114.1 - 0.044 12.7 0.0 0.09 11.7 0.0 1.4 1 0 0 1 1 1 0 Kinase-like NAP PF00956.13 CBZ53115.1 - 1.9e-56 190.8 0.0 1.9e-56 190.8 0.0 4.5 3 1 0 3 3 3 1 Nucleosome assembly protein (NAP) SRP14 PF02290.10 CBZ53116.1 - 1.6e-13 50.3 0.2 3.3e-13 49.3 0.0 1.6 2 0 0 2 2 2 1 Signal recognition particle 14kD protein PA14 PF07691.7 CBZ53117.1 - 5.5e-13 48.7 0.0 1.6e-12 47.2 0.0 1.8 1 0 0 1 1 1 1 PA14 domain DCX PF03607.12 CBZ53118.1 - 2.5e-09 36.5 0.0 1.3e-08 34.3 0.0 2.0 2 0 0 2 2 2 1 Doublecortin p25-alpha PF05517.7 CBZ53118.1 - 3.2e-08 33.9 0.1 5.8e-08 33.1 0.1 1.3 1 0 0 1 1 1 1 p25-alpha DUF1126 PF06565.7 CBZ53119.1 - 3.9e-27 93.4 1.6 1.3e-12 46.9 0.0 3.4 3 0 0 3 3 3 3 Repeat of unknown function (DUF1126) ER_lumen_recept PF00810.13 CBZ53120.1 - 4.7e-53 179.6 8.7 7e-53 179.0 6.0 1.3 1 0 0 1 1 1 1 ER lumen protein retaining receptor PQ-loop PF04193.9 CBZ53120.1 - 0.018 14.6 12.2 0.048 13.2 0.3 4.4 4 1 1 5 5 5 0 PQ loop repeat WES_acyltransf PF03007.11 CBZ53121.1 - 1e-05 25.2 5.1 0.00022 20.8 1.6 3.0 2 1 0 2 2 2 2 Wax ester synthase-like Acyl-CoA acyltransferase domain Condensation PF00668.15 CBZ53121.1 - 0.0069 15.2 0.0 0.052 12.3 0.0 2.0 1 1 0 1 1 1 1 Condensation domain SET PF00856.23 CBZ53122.1 - 4.7e-20 72.5 0.4 1.2e-19 71.1 0.0 2.0 2 0 0 2 2 2 1 SET domain SAD_SRA PF02182.12 CBZ53122.1 - 9.7e-12 44.4 0.0 3e-11 42.8 0.0 1.8 1 0 0 1 1 1 1 SAD/SRA domain Pre-SET PF05033.11 CBZ53122.1 - 2.2e-07 31.0 2.0 5.2e-07 29.8 1.4 1.7 1 0 0 1 1 1 1 Pre-SET motif DUF4583 PF15190.1 CBZ53123.1 - 0.39 10.3 0.0 0.89 9.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4583) Lebercilin PF15619.1 CBZ53123.1 - 0.49 9.7 7.8 1.1 8.6 5.4 1.5 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease zf-CSL PF05207.8 CBZ53124.1 - 3.1e-12 45.8 3.8 3.4e-11 42.4 0.9 2.9 2 1 0 2 2 2 2 CSL zinc finger Sld5 PF05916.6 CBZ53125.1 - 4.4e-05 23.7 0.2 8.3e-05 22.8 0.1 1.4 1 0 0 1 1 1 1 GINS complex protein Bax1-I PF01027.15 CBZ53127.1 - 5.2e-22 78.4 20.8 6.6e-22 78.1 14.4 1.1 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 Pyr_redox_2 PF07992.9 CBZ53128.1 - 1.9e-20 73.6 0.0 1.3e-07 31.7 0.0 4.0 3 1 1 4 4 4 3 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 CBZ53128.1 - 7.4e-16 58.3 3.6 5e-15 55.6 0.1 3.1 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 CBZ53128.1 - 1.3e-05 25.3 0.2 0.001 19.1 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 CBZ53128.1 - 6e-05 22.1 10.1 0.23 10.2 0.0 4.0 3 1 0 3 3 3 3 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 CBZ53128.1 - 0.00028 19.8 7.3 0.35 9.6 0.0 4.0 1 1 2 3 3 3 3 FAD binding domain 3HCDH_N PF02737.13 CBZ53128.1 - 0.002 17.8 0.1 0.0056 16.3 0.1 1.8 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GIDA PF01134.17 CBZ53128.1 - 0.0033 16.3 0.4 0.016 14.0 0.4 1.8 1 1 0 2 2 2 1 Glucose inhibited division protein A HI0933_like PF03486.9 CBZ53128.1 - 0.027 12.9 0.8 5.5 5.3 0.0 2.8 2 1 1 3 3 3 0 HI0933-like protein K_oxygenase PF13434.1 CBZ53128.1 - 0.03 13.2 0.3 8.9 5.1 0.1 3.0 2 1 1 3 3 3 0 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_3 PF01494.14 CBZ53128.1 - 0.2 10.6 4.8 3.2 6.6 0.0 2.5 3 0 0 3 3 3 0 FAD binding domain Shikimate_DH PF01488.15 CBZ53128.1 - 0.24 11.5 1.3 3.4 7.7 0.0 3.2 4 0 0 4 4 4 0 Shikimate / quinate 5-dehydrogenase DUF3786 PF12654.2 CBZ53129.1 - 0.11 11.7 0.0 0.23 10.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3786) WD40 PF00400.27 CBZ53130.1 - 2e-17 62.3 5.8 2.4e-06 27.1 0.0 6.0 6 0 0 6 6 6 4 WD domain, G-beta repeat PQQ_2 PF13360.1 CBZ53130.1 - 0.12 11.7 0.0 3.4 7.0 0.0 2.3 2 0 0 2 2 2 0 PQQ-like domain SGL PF08450.7 CBZ53130.1 - 0.13 11.6 0.0 7.1 5.9 0.0 2.8 3 0 0 3 3 3 0 SMP-30/Gluconolaconase/LRE-like region RPAP2_Rtr1 PF04181.8 CBZ53131.1 - 3.2e-10 39.9 0.0 1.1e-09 38.2 0.0 1.9 1 0 0 1 1 1 1 Rtr1/RPAP2 family Pkinase PF00069.20 CBZ53133.1 - 5.4e-46 156.8 0.0 3.2e-45 154.3 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ53133.1 - 2e-20 72.9 0.0 3.4e-20 72.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBZ53133.1 - 0.36 9.7 0.0 0.68 8.8 0.0 1.4 1 0 0 1 1 1 0 Kinase-like YgbB PF02542.11 CBZ53135.1 - 1.8e-40 138.3 0.0 3.3e-40 137.4 0.0 1.4 1 0 0 1 1 1 1 YgbB family DUF605 PF04652.11 CBZ53135.1 - 0.11 11.8 6.1 0.24 10.7 4.4 1.4 2 0 0 2 2 2 0 Vta1 like Phosphoprotein PF00922.12 CBZ53135.1 - 0.22 10.7 5.1 0.28 10.3 3.5 1.1 1 0 0 1 1 1 0 Vesiculovirus phosphoprotein CytochromB561_N PF09786.4 CBZ53135.1 - 1.6 7.1 5.5 2 6.7 3.8 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal tRNA_edit PF04073.10 CBZ53136.1 - 3.6e-08 33.2 0.2 3.7e-07 30.0 0.2 2.1 1 1 0 1 1 1 1 Aminoacyl-tRNA editing domain Methyltransf_23 PF13489.1 CBZ53137.1 - 1.4e-16 60.6 0.0 5e-16 58.8 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 CBZ53137.1 - 6e-16 58.7 0.0 1e-15 57.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 CBZ53137.1 - 2.2e-15 56.4 0.0 8.8e-15 54.4 0.0 1.8 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.1 CBZ53137.1 - 3.2e-10 39.8 0.0 4.3e-10 39.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CBZ53137.1 - 1.1e-09 38.6 0.0 1.9e-09 37.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CBZ53137.1 - 4.5e-07 30.1 0.0 7.7e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CBZ53137.1 - 1.5e-06 28.7 0.0 3.1e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain DUF938 PF06080.7 CBZ53137.1 - 0.098 12.1 0.0 0.2 11.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF938) MetW PF07021.7 CBZ53137.1 - 0.1 11.9 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_9 PF08003.6 CBZ53137.1 - 0.12 11.0 0.0 0.22 10.1 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1698) EF-hand_7 PF13499.1 CBZ53138.1 - 3e-10 40.0 4.0 1.1e-07 31.8 0.4 1.7 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 CBZ53138.1 - 9.3e-10 37.1 0.2 0.0007 18.7 0.1 2.3 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.1 CBZ53138.1 - 2.3e-08 33.2 0.5 0.0018 17.9 0.1 2.3 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.1 CBZ53138.1 - 6.6e-08 31.5 0.0 0.012 14.8 0.0 2.3 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.1 CBZ53138.1 - 2.7e-05 23.6 0.9 0.033 13.8 0.0 2.2 1 1 1 2 2 2 2 EF-hand domain pair SPARC_Ca_bdg PF10591.4 CBZ53138.1 - 0.00022 21.1 0.0 0.00028 20.8 0.0 1.2 1 0 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region Neur_chan_memb PF02932.11 CBZ53139.1 - 0.00097 19.0 0.0 0.0024 17.8 0.0 1.6 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region PsbN PF02468.10 CBZ53139.1 - 0.4 10.3 6.9 0.07 12.7 1.6 2.2 2 0 0 2 2 2 0 Photosystem II reaction centre N protein (psbN) zf-DHHC PF01529.15 CBZ53139.1 - 0.75 9.1 14.8 17 4.7 10.2 2.8 1 1 0 1 1 1 0 DHHC palmitoyltransferase DUF4234 PF14018.1 CBZ53139.1 - 8 6.2 8.6 0.56 9.9 0.6 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4234) Tau95 PF09734.4 CBZ53140.1 - 2.5e-44 151.8 0.0 3.7e-44 151.3 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit B9-C2 PF07162.6 CBZ53141.1 - 1.5e-40 138.7 0.0 2.3e-40 138.1 0.0 1.3 1 1 0 1 1 1 1 Ciliary basal body-associated, B9 protein Ank_2 PF12796.2 CBZ53142.1 - 8.5e-48 160.6 0.0 9.8e-18 64.2 0.0 3.5 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 CBZ53142.1 - 1.5e-32 109.7 1.6 4.8e-05 22.9 0.0 6.8 6 0 0 6 6 6 6 Ankyrin repeat Ank_4 PF13637.1 CBZ53142.1 - 4.9e-27 93.8 4.2 5.2e-09 36.3 0.0 4.9 2 2 2 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 CBZ53142.1 - 3.8e-21 73.0 1.3 0.06 13.6 0.0 6.8 6 0 0 6 6 6 6 Ankyrin repeat RNA_GG_bind PF10258.4 CBZ53142.1 - 4.4e-18 64.7 0.5 9e-18 63.7 0.3 1.5 1 0 0 1 1 1 1 PHAX RNA-binding domain Ank_5 PF13857.1 CBZ53142.1 - 5.1e-16 58.3 7.7 0.00012 22.2 0.2 5.9 4 1 2 6 6 6 5 Ankyrin repeats (many copies) TPR_19 PF14559.1 CBZ53143.1 - 2e-12 47.2 5.5 0.0021 18.3 0.0 6.6 4 1 4 8 8 8 3 Tetratricopeptide repeat TPR_14 PF13428.1 CBZ53143.1 - 1.4e-08 34.6 5.0 0.38 11.5 0.0 7.2 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_16 PF13432.1 CBZ53143.1 - 4.8e-08 33.4 8.2 0.01 16.5 1.1 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat Apc3 PF12895.2 CBZ53143.1 - 4.9e-08 32.9 28.3 0.017 15.2 0.1 6.8 3 2 3 7 7 7 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.1 CBZ53143.1 - 3.6e-07 29.7 20.2 0.008 15.7 1.4 6.8 6 1 0 6 6 6 2 TPR repeat TPR_12 PF13424.1 CBZ53143.1 - 8.6e-07 28.8 13.9 0.0045 16.8 0.0 6.7 7 2 1 8 8 8 2 Tetratricopeptide repeat PPR PF01535.15 CBZ53143.1 - 0.0006 19.6 0.2 7.4 6.7 0.0 5.0 6 0 0 6 6 5 1 PPR repeat TPR_4 PF07721.9 CBZ53143.1 - 0.00097 19.3 9.7 0.41 11.2 0.0 5.9 7 0 0 7 7 5 1 Tetratricopeptide repeat TPR_1 PF00515.23 CBZ53143.1 - 0.003 17.0 16.4 0.25 10.9 0.2 5.1 5 0 0 5 5 5 3 Tetratricopeptide repeat Type_III_YscG PF09477.5 CBZ53143.1 - 0.011 15.7 2.2 0.39 10.8 0.0 3.8 5 0 0 5 5 4 0 Bacterial type II secretion system chaperone protein (type_III_yscG) TPR_8 PF13181.1 CBZ53143.1 - 0.064 13.0 6.8 4.7 7.2 0.1 5.0 6 0 0 6 6 6 0 Tetratricopeptide repeat ARD PF03079.9 CBZ53143.1 - 0.12 12.2 0.2 0.23 11.3 0.2 1.4 1 0 0 1 1 1 0 ARD/ARD' family TPR_9 PF13371.1 CBZ53143.1 - 0.17 11.7 13.1 0.8 9.6 0.2 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.12 CBZ53143.1 - 0.24 11.4 26.4 0.26 11.2 0.1 7.0 9 0 0 9 9 7 0 Tetratricopeptide repeat TPR_6 PF13174.1 CBZ53143.1 - 3.1 8.4 20.0 1.6 9.3 0.0 6.7 8 0 0 8 8 6 0 Tetratricopeptide repeat Thioredoxin PF00085.15 CBZ53145.1 - 9.4e-19 67.0 0.0 1.7e-18 66.2 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 CBZ53145.1 - 0.00014 22.0 0.0 0.00027 21.1 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 CBZ53145.1 - 0.0031 17.5 0.0 0.0074 16.3 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_7 PF13899.1 CBZ53145.1 - 0.0037 17.2 0.1 0.01 15.8 0.1 1.7 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_9 PF14595.1 CBZ53145.1 - 0.012 15.1 0.0 0.026 14.0 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin AhpC-TSA PF00578.16 CBZ53145.1 - 0.04 13.6 0.0 0.079 12.6 0.0 1.4 1 0 0 1 1 1 0 AhpC/TSA family Thioredoxin_6 PF13848.1 CBZ53145.1 - 0.072 12.8 0.1 2.6 7.7 0.0 2.4 2 0 0 2 2 2 0 Thioredoxin-like domain DSBA PF01323.15 CBZ53145.1 - 0.12 11.9 0.1 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 DSBA-like thioredoxin domain MMR_HSR1 PF01926.18 CBZ53146.1 - 4.4e-17 62.0 0.0 1.1e-16 60.7 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 CBZ53146.1 - 0.0051 16.6 0.8 1.2 8.9 0.0 2.9 2 1 0 3 3 3 2 Dynamin family FeoB_N PF02421.13 CBZ53146.1 - 0.026 13.7 0.1 0.13 11.5 0.0 2.1 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_16 PF13191.1 CBZ53146.1 - 0.1 12.5 3.4 0.62 10.0 0.0 3.2 3 0 0 3 3 3 0 AAA ATPase domain SDA1 PF05285.7 CBZ53146.1 - 0.43 9.8 8.8 0.11 11.7 3.8 1.7 2 0 0 2 2 2 0 SDA1 Nop14 PF04147.7 CBZ53146.1 - 0.59 7.9 7.1 0.83 7.4 4.9 1.1 1 0 0 1 1 1 0 Nop14-like family EGF PF00008.22 CBZ53147.1 - 7.9e-34 115.2 355.1 0.023 14.6 5.0 33.6 32 2 1 33 33 33 31 EGF-like domain cEGF PF12662.2 CBZ53147.1 - 1.9e-17 62.5 282.9 0.001 18.6 0.8 32.5 31 1 0 31 31 31 20 Complement Clr-like EGF-like FXa_inhibition PF14670.1 CBZ53147.1 - 4e-10 39.6 399.4 0.021 14.9 4.2 32.3 26 6 6 32 32 32 22 Coagulation Factor Xa inhibitory site EGF_3 PF12947.2 CBZ53147.1 - 1.7e-09 37.4 305.4 0.00012 21.9 2.9 32.2 32 0 0 32 32 32 15 EGF domain Plasmod_Pvs28 PF06247.6 CBZ53147.1 - 0.00012 21.6 249.5 0.00036 20.1 14.4 14.5 1 1 11 13 13 13 7 Plasmodium ookinete surface protein Pvs28 GST_C_2 PF13410.1 CBZ53149.1 - 0.00069 19.4 0.0 0.0015 18.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Tom37_C PF11801.3 CBZ53149.1 - 0.0032 17.3 0.0 0.023 14.5 0.0 2.1 2 0 0 2 2 2 1 Tom37 C-terminal domain GST_C_3 PF14497.1 CBZ53149.1 - 0.029 14.8 1.4 0.04 14.4 0.0 2.0 3 0 0 3 3 3 0 Glutathione S-transferase, C-terminal domain Pheromone PF08015.6 CBZ53149.1 - 6.8 7.5 13.0 1.6 9.6 1.1 3.2 2 0 0 2 2 2 0 Fungal mating-type pheromone Rad9 PF04139.8 CBZ53150.1 - 3.1e-14 52.7 0.0 1.6e-13 50.3 0.0 1.9 1 1 0 1 1 1 1 Rad9 PCNA_N PF00705.13 CBZ53150.1 - 0.065 12.7 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Proliferating cell nuclear antigen, N-terminal domain Actin PF00022.14 CBZ53151.1 - 7.6e-55 185.9 0.0 1.2e-34 119.3 0.0 2.2 2 0 0 2 2 2 2 Actin Myc_N PF01056.13 CBZ53153.1 - 0.62 9.1 8.7 0.74 8.9 6.0 1.0 1 0 0 1 1 1 0 Myc amino-terminal region DUF4337 PF14235.1 CBZ53153.1 - 2.8 7.7 9.1 3.5 7.4 6.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) DUF809 PF05663.6 CBZ53153.1 - 4.2 7.3 9.1 5 7.0 6.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF809) DUF1510 PF07423.6 CBZ53153.1 - 5.8 6.2 15.6 6.7 6.0 10.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Vfa1 PF08432.5 CBZ53153.1 - 8.9 6.2 15.1 11 6.0 10.4 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF3357 PF11837.3 CBZ53154.1 - 0.047 13.5 0.7 9.1 6.1 0.0 3.5 4 0 0 4 4 4 0 Domain of unknown function (DUF3357) DUF2484 PF10658.4 CBZ53154.1 - 0.049 13.7 1.7 0.57 10.3 0.3 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2484) ER_lumen_recept PF00810.13 CBZ53154.1 - 0.47 10.9 13.2 1.1 9.7 0.0 4.2 4 1 0 4 4 4 0 ER lumen protein retaining receptor Cation_ATPase_C PF00689.16 CBZ53154.1 - 0.66 9.4 4.6 2.1 7.8 0.0 2.9 3 0 0 3 3 3 0 Cation transporting ATPase, C-terminus EF-hand_7 PF13499.1 CBZ53155.1 - 0.00015 21.7 0.3 0.022 14.9 0.0 2.3 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.1 CBZ53155.1 - 0.0015 18.2 0.0 0.0066 16.2 0.0 2.2 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.27 CBZ53155.1 - 0.017 14.3 0.0 0.15 11.4 0.0 2.6 2 0 0 2 2 2 0 EF hand PIH1 PF08190.7 CBZ53158.1 - 0.00015 21.3 27.7 0.18 11.1 0.0 6.3 4 2 1 6 6 6 4 pre-RNA processing PIH1/Nop17 THF_DHG_CYH_C PF02882.14 CBZ53159.1 - 8.6e-42 141.9 0.7 1.3e-31 108.9 0.1 2.2 2 0 0 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.18 CBZ53159.1 - 8.7e-05 22.5 0.0 0.00023 21.1 0.0 1.7 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain Neurensin PF14927.1 CBZ53160.1 - 0.29 10.5 0.1 12 5.2 0.0 2.3 1 1 1 2 2 2 0 Neurensin SET PF00856.23 CBZ53161.1 - 4.2e-05 23.9 13.7 0.027 14.7 0.0 4.7 3 1 0 3 3 3 2 SET domain Lipoprotein_7 PF01540.11 CBZ53162.1 - 2.3e-05 23.6 19.6 0.00026 20.1 13.7 1.9 1 1 0 1 1 1 1 Adhesin lipoprotein Herpes_U30 PF04523.8 CBZ53162.1 - 0.001 16.6 2.0 0.0011 16.5 1.4 1.1 1 0 0 1 1 1 1 Herpes virus tegument protein U30 COG5 PF10392.4 CBZ53162.1 - 0.0012 18.8 4.9 0.0049 16.8 3.4 2.0 1 1 0 1 1 1 1 Golgi transport complex subunit 5 Prominin PF05478.6 CBZ53162.1 - 0.0039 14.7 2.8 0.0044 14.6 2.0 1.2 1 0 0 1 1 1 1 Prominin DUF812 PF05667.6 CBZ53162.1 - 0.0043 15.6 11.7 0.0047 15.5 8.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF812) IncA PF04156.9 CBZ53162.1 - 0.0049 16.4 5.5 0.0057 16.2 3.8 1.3 1 0 0 1 1 1 1 IncA protein AAA_13 PF13166.1 CBZ53162.1 - 0.011 14.3 14.3 0.016 13.7 9.9 1.4 1 0 0 1 1 1 0 AAA domain MCPsignal PF00015.16 CBZ53162.1 - 0.011 15.3 11.2 0.015 14.8 7.8 1.3 1 0 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain IFT57 PF10498.4 CBZ53162.1 - 0.014 14.1 11.3 0.015 14.0 7.8 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 TMPIT PF07851.8 CBZ53162.1 - 0.015 14.4 11.9 0.02 13.9 8.3 1.2 1 0 0 1 1 1 0 TMPIT-like protein DUF3450 PF11932.3 CBZ53162.1 - 0.016 14.4 3.0 0.023 13.9 2.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Syntaxin-6_N PF09177.6 CBZ53162.1 - 0.018 15.3 7.3 0.34 11.3 4.2 2.5 1 1 0 1 1 1 0 Syntaxin 6, N-terminal DUF4239 PF14023.1 CBZ53162.1 - 0.019 14.3 0.5 0.026 13.8 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4239) APG6 PF04111.7 CBZ53162.1 - 0.025 13.6 8.4 0.039 13.0 5.8 1.4 1 0 0 1 1 1 0 Autophagy protein Apg6 APG17 PF04108.7 CBZ53162.1 - 0.03 13.1 5.4 0.045 12.5 3.7 1.4 1 0 0 1 1 1 0 Autophagy protein Apg17 Laminin_II PF06009.7 CBZ53162.1 - 0.035 13.8 16.4 0.052 13.3 11.4 1.2 1 0 0 1 1 1 0 Laminin Domain II Corona_S2 PF01601.11 CBZ53162.1 - 0.044 11.8 1.7 0.051 11.6 1.2 1.1 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein Baculo_PEP_C PF04513.7 CBZ53162.1 - 0.046 13.5 2.0 0.12 12.1 1.4 1.7 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF964 PF06133.6 CBZ53162.1 - 0.09 12.7 13.5 1.3 9.1 0.9 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF964) Peptidase_C6 PF00851.13 CBZ53162.1 - 0.1 11.2 8.7 0.11 11.1 6.0 1.0 1 0 0 1 1 1 0 Helper component proteinase DUF2450 PF10475.4 CBZ53162.1 - 0.12 11.2 8.0 0.19 10.5 5.6 1.4 1 0 0 1 1 1 0 Protein of unknown function N-terminal domain (DUF2450) Effector_1 PF04518.7 CBZ53162.1 - 0.19 10.6 7.1 0.25 10.3 4.9 1.2 1 0 0 1 1 1 0 Effector from type III secretion system Tweety PF04906.8 CBZ53162.1 - 0.29 9.4 2.1 0.38 9.1 1.4 1.2 1 0 0 1 1 1 0 Tweety DUF334 PF03904.8 CBZ53162.1 - 0.35 10.1 14.2 0.49 9.6 9.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF334) Phage_GP20 PF06810.6 CBZ53162.1 - 0.49 9.8 22.2 4 6.8 15.2 2.0 1 1 0 1 1 1 0 Phage minor structural protein GP20 NikR_C PF08753.6 CBZ53162.1 - 0.68 9.8 6.7 8 6.4 0.4 2.6 2 1 0 2 2 2 0 NikR C terminal nickel binding domain DUF1664 PF07889.7 CBZ53162.1 - 0.7 9.7 15.5 1.5 8.6 5.9 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Syntaxin PF00804.20 CBZ53162.1 - 0.72 10.0 23.5 2.4 8.3 9.8 2.9 1 1 2 3 3 3 0 Syntaxin DUF2115 PF09888.4 CBZ53162.1 - 1.1 9.3 7.1 1.5 8.8 4.9 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2115) HSCB_C PF07743.8 CBZ53162.1 - 1.1 9.7 7.7 9 6.8 4.2 2.7 1 1 1 2 2 2 0 HSCB C-terminal oligomerisation domain DivIC PF04977.10 CBZ53162.1 - 1.2 8.7 21.7 0.089 12.2 4.6 2.7 1 1 1 2 2 2 0 Septum formation initiator Fib_alpha PF08702.5 CBZ53162.1 - 1.6 8.8 13.0 1.4 9.0 7.4 2.0 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF1515 PF07439.6 CBZ53162.1 - 1.7 8.5 10.1 2.5 7.9 1.2 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF1515) TMCO5 PF14992.1 CBZ53162.1 - 1.7 7.7 14.2 2.3 7.3 9.9 1.2 1 0 0 1 1 1 0 TMCO5 family V_ATPase_I PF01496.14 CBZ53162.1 - 1.7 6.4 9.6 2.1 6.1 6.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Ribosomal_L30 PF00327.15 CBZ53162.1 - 1.9 8.1 8.7 15 5.2 0.2 3.5 1 1 2 3 3 3 0 Ribosomal protein L30p/L7e phiKZ_IP PF12699.2 CBZ53162.1 - 2 7.2 19.6 1.7 7.5 8.9 2.1 1 1 1 2 2 2 0 phiKZ-like phage internal head proteins Syntaxin_2 PF14523.1 CBZ53162.1 - 2 8.4 18.3 1.1e+02 2.8 12.7 2.6 1 1 0 1 1 1 0 Syntaxin-like protein BLOC1_2 PF10046.4 CBZ53162.1 - 2.3 8.4 15.7 8 6.6 9.6 2.2 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Atg14 PF10186.4 CBZ53162.1 - 2.3 7.0 14.6 2.5 6.9 10.1 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF972 PF06156.8 CBZ53162.1 - 2.5 8.4 11.5 8.2 6.8 7.8 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF972) Seryl_tRNA_N PF02403.17 CBZ53162.1 - 2.6 8.1 29.2 3.9 7.5 11.2 2.2 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Laminin_I PF06008.9 CBZ53162.1 - 3.2 6.9 14.8 5.2 6.2 8.0 1.9 1 1 1 2 2 2 0 Laminin Domain I DASH_Dad4 PF08650.5 CBZ53162.1 - 3.5 7.6 8.2 33 4.5 5.7 2.2 1 1 0 1 1 1 0 DASH complex subunit Dad4 DUF1319 PF07028.6 CBZ53162.1 - 4.1 7.6 16.9 5.8 7.1 5.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1319) DASH_Duo1 PF08651.5 CBZ53162.1 - 4.2 7.0 14.5 2.2 7.9 1.7 3.1 2 1 1 3 3 3 0 DASH complex subunit Duo1 Phage_Gp19 PF09355.5 CBZ53162.1 - 4.7 7.0 6.2 2.3 8.1 2.2 1.9 1 1 1 2 2 2 0 Phage protein Gp19/Gp15/Gp42 DUF948 PF06103.6 CBZ53162.1 - 4.8 7.1 9.9 62 3.5 6.9 2.5 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) BRO1 PF03097.13 CBZ53162.1 - 5 5.7 10.3 2.8 6.6 4.6 1.8 1 1 1 2 2 2 0 BRO1-like domain ApoL PF05461.6 CBZ53162.1 - 6.1 6.0 12.5 3.5 6.7 3.4 2.0 1 1 1 2 2 2 0 Apolipoprotein L Fzo_mitofusin PF04799.8 CBZ53162.1 - 6.9 6.0 11.3 1.7 8.0 1.8 2.2 1 1 1 2 2 2 0 fzo-like conserved region COG2 PF06148.6 CBZ53162.1 - 6.9 6.5 11.2 15 5.5 4.5 2.4 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Sipho_Gp157 PF05565.6 CBZ53162.1 - 7.2 6.1 26.5 3.1 7.3 4.2 2.1 1 1 1 2 2 2 0 Siphovirus Gp157 Uso1_p115_C PF04871.8 CBZ53162.1 - 7.3 6.5 18.0 3.3e+02 1.1 12.5 2.2 1 1 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region WD40 PF00400.27 CBZ53166.1 - 1.2e-16 59.8 10.6 4.1e-06 26.4 0.5 6.5 7 0 0 7 7 7 4 WD domain, G-beta repeat DNA_pol_phi PF04931.8 CBZ53166.1 - 7.4 4.2 10.6 12 3.4 7.3 1.2 1 0 0 1 1 1 0 DNA polymerase phi MFS_1 PF07690.11 CBZ53169.1 - 7e-15 54.5 55.3 3.8e-13 48.8 24.8 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Dexa_ind PF15198.1 CBZ53169.1 - 2.7 7.9 7.4 0.4 10.6 0.9 2.8 2 1 1 3 3 3 0 Dexamethasone-induced Synaptobrevin PF00957.16 CBZ53170.1 - 4.3e-21 74.3 2.1 6.4e-21 73.7 1.5 1.3 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.1 CBZ53170.1 - 0.008 15.7 0.0 0.015 14.8 0.0 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain Sec20 PF03908.8 CBZ53170.1 - 0.64 9.7 2.8 2.1 8.1 1.9 2.0 1 1 0 1 1 1 0 Sec20 CDP-OH_P_transf PF01066.16 CBZ53171.1 - 4.2e-19 68.7 4.0 4.2e-19 68.7 2.8 2.6 3 1 1 4 4 4 1 CDP-alcohol phosphatidyltransferase Hydrolase_4 PF12146.3 CBZ53172.1 - 1.8e-08 34.0 0.3 5.7e-05 22.9 0.0 2.7 2 0 0 2 2 2 2 Putative lysophospholipase Abhydrolase_6 PF12697.2 CBZ53172.1 - 8.3e-08 32.3 0.9 8.3e-08 32.3 0.6 3.5 5 0 0 5 5 5 2 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CBZ53172.1 - 2.7e-07 30.4 2.0 2.6e-06 27.2 1.2 2.6 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CBZ53172.1 - 0.12 11.9 0.1 0.22 11.0 0.1 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Prefoldin PF02996.12 CBZ53173.1 - 5.7e-21 74.3 3.4 2.5e-18 65.8 0.2 2.1 2 0 0 2 2 2 2 Prefoldin subunit Pol_alpha_B_N PF08418.5 CBZ53173.1 - 0.011 15.3 0.3 0.011 15.3 0.2 1.6 2 0 0 2 2 2 0 DNA polymerase alpha subunit B N-terminal DUF3322 PF11795.3 CBZ53173.1 - 0.046 13.3 1.0 0.14 11.7 0.0 2.1 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria N-term (DUF3322) SCO1-SenC PF02630.9 CBZ53176.1 - 3.5e-48 163.5 0.0 4.2e-48 163.2 0.0 1.1 1 0 0 1 1 1 1 SCO1/SenC Thioredoxin_8 PF13905.1 CBZ53176.1 - 0.0084 16.1 0.1 0.022 14.8 0.0 1.8 2 1 0 2 2 2 1 Thioredoxin-like AhpC-TSA PF00578.16 CBZ53176.1 - 0.02 14.5 0.0 0.03 14.0 0.0 1.3 1 0 0 1 1 1 0 AhpC/TSA family DUF1191 PF06697.7 CBZ53179.1 - 0.03 13.1 0.3 0.047 12.4 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) Malectin_like PF12819.2 CBZ53179.1 - 0.13 11.2 0.1 0.19 10.7 0.0 1.2 1 0 0 1 1 1 0 Carbohydrate-binding protein of the ER MMR_HSR1 PF01926.18 CBZ53180.1 - 5.6e-17 61.7 0.0 1.5e-16 60.4 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 CBZ53180.1 - 0.00053 19.3 0.0 0.0009 18.5 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.18 CBZ53180.1 - 0.0069 16.2 0.0 0.14 11.9 0.1 2.4 1 1 1 2 2 2 1 Dynamin family DUF258 PF03193.11 CBZ53180.1 - 0.013 14.6 0.0 0.028 13.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 CBZ53180.1 - 0.072 12.5 0.0 0.23 10.8 0.0 1.8 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain UvrD-helicase PF00580.16 CBZ53181.1 - 0.0048 16.2 0.0 0.0066 15.7 0.0 1.2 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain Inhibitor_I42 PF09394.5 CBZ53181.1 - 0.058 13.7 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 Chagasin family peptidase inhibitor I42 Rib PF08428.5 CBZ53181.1 - 0.059 13.1 0.5 0.83 9.4 0.1 2.2 2 0 0 2 2 2 0 Rib/alpha-like repeat MIF4G PF02854.14 CBZ53184.1 - 7.7e-28 97.3 0.2 9.8e-28 96.9 0.2 1.1 1 0 0 1 1 1 1 MIF4G domain Ras PF00071.17 CBZ53185.1 - 7e-58 194.5 0.1 8.1e-58 194.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CBZ53185.1 - 1.4e-21 77.1 0.0 1.9e-21 76.7 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CBZ53185.1 - 4.4e-15 55.3 0.0 5.5e-15 55.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 CBZ53185.1 - 2.9e-07 30.1 0.0 1.1e-05 24.9 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 CBZ53185.1 - 2.4e-05 24.2 0.0 3.7e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.12 CBZ53185.1 - 0.00036 20.1 0.0 0.067 12.7 0.0 2.2 1 1 1 2 2 2 2 Conserved hypothetical ATP binding protein Gtr1_RagA PF04670.7 CBZ53185.1 - 0.00099 18.3 0.0 0.0013 17.9 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_22 PF13401.1 CBZ53185.1 - 0.0053 16.8 0.0 0.016 15.3 0.0 1.7 1 1 0 1 1 1 1 AAA domain ArgK PF03308.11 CBZ53185.1 - 0.02 13.6 0.1 0.65 8.7 0.0 2.1 2 0 0 2 2 2 0 ArgK protein FeoB_N PF02421.13 CBZ53185.1 - 0.028 13.7 0.0 0.25 10.6 0.0 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B NACHT PF05729.7 CBZ53185.1 - 0.039 13.6 0.0 0.068 12.8 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_16 PF13191.1 CBZ53185.1 - 0.08 12.9 0.1 0.23 11.4 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain SRPRB PF09439.5 CBZ53185.1 - 0.11 11.7 0.0 0.14 11.3 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit PduV-EutP PF10662.4 CBZ53185.1 - 0.12 11.8 0.1 0.61 9.5 0.0 2.0 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation cobW PF02492.14 CBZ53185.1 - 0.22 10.9 0.9 1.1 8.6 0.0 2.3 2 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain CS PF04969.11 CBZ53187.1 - 1.8e-08 34.7 0.0 3.7e-08 33.7 0.0 1.5 1 0 0 1 1 1 1 CS domain PIH1 PF08190.7 CBZ53187.1 - 0.0059 16.0 0.1 0.075 12.4 0.0 2.1 2 0 0 2 2 2 1 pre-RNA processing PIH1/Nop17 PTS_2-RNA PF01885.11 CBZ53189.1 - 5.3e-45 153.0 0.0 8.6e-45 152.3 0.0 1.3 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family SbcCD_C PF13558.1 CBZ53190.1 - 1.7e-08 34.2 0.0 8.8e-08 31.9 0.0 2.3 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_21 PF13304.1 CBZ53190.1 - 5.7e-07 29.7 0.0 0.035 14.0 0.0 2.8 3 0 0 3 3 3 2 AAA domain AAA_15 PF13175.1 CBZ53190.1 - 4.8e-05 22.5 0.0 0.0024 16.9 0.0 3.1 3 0 0 3 3 3 1 AAA ATPase domain SMC_N PF02463.14 CBZ53190.1 - 4.8e-05 22.6 28.4 0.00074 18.8 19.7 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 CBZ53190.1 - 0.00024 21.5 49.2 0.00024 21.5 34.1 7.7 3 2 0 3 3 3 1 AAA domain ABC_tran PF00005.22 CBZ53190.1 - 0.015 15.5 0.0 0.015 15.5 0.0 6.3 6 2 1 7 7 7 0 ABC transporter AAA_29 PF13555.1 CBZ53190.1 - 0.027 13.9 0.0 0.076 12.5 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_13 PF13166.1 CBZ53190.1 - 0.07 11.5 0.0 0.07 11.5 0.0 8.2 6 1 1 7 7 7 0 AAA domain NOT2_3_5 PF04153.13 CBZ53193.1 - 8.5e-20 71.0 3.6 1.8e-19 69.9 0.0 2.8 3 0 0 3 3 3 1 NOT2 / NOT3 / NOT5 family Med15 PF09606.5 CBZ53193.1 - 0.0081 14.4 27.5 0.015 13.4 19.0 1.4 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal PAT1 PF09770.4 CBZ53193.1 - 0.56 8.3 19.4 0.74 7.9 13.5 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 zf-CCCH PF00642.19 CBZ53194.1 - 1e-08 34.6 15.3 0.0011 18.5 1.9 3.9 3 0 0 3 3 3 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 CBZ53194.1 - 0.00045 20.1 11.7 0.57 10.2 0.8 3.9 3 0 0 3 3 3 3 Zinc finger C-x8-C-x5-C-x3-H type Sugar_tr PF00083.19 CBZ53195.1 - 1.5e-64 218.2 26.9 1.9e-64 217.9 18.7 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CBZ53195.1 - 2.4e-18 65.9 38.5 1.3e-17 63.5 26.8 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 CBZ53195.1 - 0.00015 20.1 3.7 0.00022 19.5 2.6 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Peptidase_M76 PF09768.4 CBZ53196.1 - 1.2e-33 116.0 0.0 3.9e-24 85.0 0.0 2.2 2 0 0 2 2 2 2 Peptidase M76 family NAC PF01849.13 CBZ53198.1 - 2.7e-18 65.2 0.0 4.9e-18 64.4 0.0 1.4 1 0 0 1 1 1 1 NAC domain COQ9 PF08511.6 CBZ53198.1 - 0.098 12.1 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 COQ9 PDEase_I PF00233.14 CBZ53199.1 - 4.8e-55 186.8 0.6 7.3e-55 186.2 0.4 1.2 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase GET2 PF08690.5 CBZ53199.1 - 0.67 9.1 0.0 1.2 8.3 0.0 1.3 1 0 0 1 1 1 0 GET complex subunit GET2 SUI1 PF01253.17 CBZ53201.1 - 3.7e-19 68.3 0.1 8.5e-19 67.1 0.1 1.6 1 0 0 1 1 1 1 Translation initiation factor SUI1 Pkinase PF00069.20 CBZ53202.1 - 8.5e-28 97.2 0.0 3.4e-23 82.1 0.0 2.6 1 1 2 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ53202.1 - 1.5e-10 40.5 0.0 2.8e-10 39.7 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBZ53202.1 - 0.0032 16.4 0.0 0.0053 15.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 CBZ53202.1 - 0.036 13.7 0.4 0.08 12.6 0.3 1.8 1 1 0 1 1 1 0 Phosphotransferase enzyme family Pantoate_transf PF02548.10 CBZ53203.1 - 2.2e-78 262.9 1.8 3.3e-78 262.3 1.3 1.2 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase ApbA_C PF08546.6 CBZ53203.1 - 3e-35 120.9 0.2 9.7e-35 119.2 0.1 1.9 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.11 CBZ53203.1 - 1.1e-16 60.6 0.0 1.1e-15 57.4 0.0 2.3 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA PEP_mutase PF13714.1 CBZ53203.1 - 0.001 18.3 0.1 0.0032 16.7 0.1 1.8 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase TB2_DP1_HVA22 PF03134.14 CBZ53204.1 - 2.9e-34 116.6 3.8 5.3e-34 115.8 2.6 1.4 1 0 0 1 1 1 1 TB2/DP1, HVA22 family DUF2228 PF10228.4 CBZ53205.1 - 3.5e-19 69.3 0.0 1.4e-16 60.8 0.0 2.2 2 0 0 2 2 2 2 Uncharacterised conserved protein (DUF2228) Nsp1 PF11501.3 CBZ53205.1 - 0.048 13.5 0.0 0.1 12.4 0.0 1.5 1 0 0 1 1 1 0 Non structural protein Nsp1 DUF974 PF06159.8 CBZ53206.1 - 1.2e-12 47.8 0.0 4.8e-06 26.2 0.0 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF974) Trs65 PF12735.2 CBZ53206.1 - 0.0021 17.4 0.1 0.11 11.7 0.0 2.8 3 1 0 3 3 3 1 TRAPP trafficking subunit Trs65 SPOUT_MTase PF02590.12 CBZ53206.1 - 0.041 13.5 0.0 0.059 13.0 0.0 1.2 1 0 0 1 1 1 0 Predicted SPOUT methyltransferase Peptidase_M16_C PF05193.16 CBZ53207.1 - 1.1e-13 51.2 0.4 1.4e-11 44.3 0.0 2.9 3 0 0 3 3 3 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 CBZ53207.1 - 0.0028 17.4 1.1 0.7 9.6 0.0 3.5 3 1 0 3 3 3 2 Insulinase (Peptidase family M16) Na_sulph_symp PF00939.14 CBZ53208.1 - 9.8e-48 163.1 7.1 3.7e-28 98.6 0.5 2.1 2 0 0 2 2 2 2 Sodium:sulfate symporter transmembrane region CitMHS PF03600.11 CBZ53208.1 - 1.6e-09 36.8 28.4 2.8e-05 22.8 6.4 2.9 3 0 0 3 3 3 2 Citrate transporter tRNA-synt_2b PF00587.20 CBZ53209.1 - 6.5e-58 195.1 0.0 3.3e-57 192.8 0.0 1.9 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 CBZ53209.1 - 6.3e-21 74.1 0.1 1.2e-19 70.0 0.0 2.6 2 0 0 2 2 2 1 Anticodon binding domain WHEP-TRS PF00458.15 CBZ53209.1 - 0.00015 21.3 3.3 0.00028 20.4 1.2 2.3 2 0 0 2 2 2 1 WHEP-TRS domain Spc7 PF08317.6 CBZ53209.1 - 0.023 13.3 0.7 0.044 12.4 0.5 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein Apolipoprotein PF01442.13 CBZ53209.1 - 0.035 13.6 4.4 0.7 9.3 2.4 2.4 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain Atg14 PF10186.4 CBZ53209.1 - 1.9 7.3 6.3 0.16 10.8 0.5 2.0 3 0 0 3 3 3 0 UV radiation resistance protein and autophagy-related subunit 14 Acyltransferase PF01553.16 CBZ53210.1 - 7.5e-15 54.5 0.0 6.3e-07 28.9 0.0 2.4 2 0 0 2 2 2 2 Acyltransferase DUF3529 PF12046.3 CBZ53210.1 - 0.11 11.4 0.7 0.2 10.6 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3529) ATP-synt_ab PF00006.20 CBZ53211.1 - 1.2e-109 364.8 0.0 1.8e-109 364.3 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 CBZ53211.1 - 4.9e-24 84.9 0.0 8.6e-24 84.1 0.0 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain AAA_31 PF13614.1 CBZ53211.1 - 0.057 13.3 0.0 0.2 11.6 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.1 CBZ53211.1 - 0.13 12.1 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain PIP5K PF01504.13 CBZ53212.1 - 4.7e-33 114.3 0.0 5.1e-20 71.6 0.0 2.3 2 0 0 2 2 2 2 Phosphatidylinositol-4-phosphate 5-Kinase FYVE PF01363.16 CBZ53212.1 - 1.3e-11 44.1 14.9 8.8e-11 41.5 10.3 2.5 1 0 0 1 1 1 1 FYVE zinc finger Cpn60_TCP1 PF00118.19 CBZ53212.1 - 0.00035 19.3 0.0 0.00091 17.9 0.0 1.6 2 0 0 2 2 2 1 TCP-1/cpn60 chaperonin family BRO1 PF03097.13 CBZ53213.1 - 6.7e-32 110.6 0.3 3.6e-31 108.2 0.0 2.2 2 1 0 2 2 2 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.1 CBZ53213.1 - 2.4e-11 43.1 16.9 2.7e-10 39.6 11.7 2.7 1 1 0 1 1 1 1 ALIX V-shaped domain binding to HIV DEAD PF00270.24 CBZ53214.1 - 6.9e-30 103.7 0.0 6.2e-21 74.6 0.0 2.4 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.26 CBZ53214.1 - 8.6e-16 57.5 0.0 1.7e-15 56.6 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 CBZ53214.1 - 0.15 12.1 0.2 4.5 7.4 0.0 2.8 3 0 0 3 3 3 0 AAA domain Pkinase PF00069.20 CBZ53215.1 - 8.8e-28 97.1 7.0 4.8e-14 52.1 0.0 4.8 5 1 0 5 5 5 3 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ53215.1 - 1.3e-10 40.8 0.0 3.6e-06 26.2 0.0 3.3 3 0 0 3 3 3 3 Protein tyrosine kinase Clathrin PF00637.15 CBZ53216.1 - 6.8e-10 38.7 0.2 0.00095 18.7 0.0 3.6 2 1 1 3 3 3 3 Region in Clathrin and VPS Coatomer_WDAD PF04053.9 CBZ53216.1 - 1.6e-06 27.1 3.5 0.00013 20.8 0.3 4.0 5 0 0 5 5 5 1 Coatomer WD associated region WD40 PF00400.27 CBZ53216.1 - 0.00012 21.8 2.8 0.87 9.5 0.0 4.3 4 0 0 4 4 4 2 WD domain, G-beta repeat TPR_7 PF13176.1 CBZ53216.1 - 0.00015 21.2 8.9 0.74 9.7 0.0 6.7 4 3 1 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.1 CBZ53216.1 - 0.017 15.6 12.7 10 7.0 0.0 6.9 4 3 2 6 6 6 0 Tetratricopeptide repeat PhyH PF05721.8 CBZ53216.1 - 0.03 14.3 0.0 0.08 12.9 0.0 1.7 1 0 0 1 1 1 0 Phytanoyl-CoA dioxygenase (PhyH) TPR_1 PF00515.23 CBZ53216.1 - 0.15 11.7 5.2 6.8 6.4 0.0 5.2 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_11 PF13414.1 CBZ53216.1 - 0.45 10.1 6.0 1.5 8.5 0.0 4.3 5 0 0 5 5 5 0 TPR repeat TPR_2 PF07719.12 CBZ53216.1 - 5.9 7.0 9.5 2 8.5 0.0 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat Trichoplein PF13868.1 CBZ53217.1 - 0.00037 19.0 133.5 0.00037 19.0 92.5 2.1 1 1 1 2 2 2 1 Tumour suppressor, Mitostatin EST1 PF10374.4 CBZ53218.1 - 0.11 12.5 0.0 0.31 11.0 0.0 1.8 1 0 0 1 1 1 0 Telomerase activating protein Est1 Pkinase PF00069.20 CBZ53219.1 - 3.8e-43 147.4 0.0 5.2e-40 137.2 0.0 2.6 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ53219.1 - 8.1e-15 54.5 0.0 3e-11 42.8 0.0 3.3 3 1 0 3 3 3 2 Protein tyrosine kinase APH PF01636.18 CBZ53219.1 - 0.0015 18.3 0.0 0.005 16.5 0.0 2.0 1 0 0 1 1 1 1 Phosphotransferase enzyme family SPC25 PF06703.6 CBZ53220.1 - 1.5e-14 53.9 0.2 2.3e-14 53.2 0.1 1.3 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) DUF4505 PF14956.1 CBZ53220.1 - 0.025 14.2 0.1 0.034 13.7 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4505) MaoC_dehydratas PF01575.14 CBZ53221.1 - 4.1e-25 87.5 0.0 6.8e-25 86.8 0.0 1.3 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.1 CBZ53221.1 - 6.6e-10 38.8 0.0 0.00019 21.2 0.0 2.2 2 0 0 2 2 2 2 N-terminal half of MaoC dehydratase MFS_1 PF07690.11 CBZ53222.1 - 3.5e-30 104.9 9.5 9.3e-19 67.3 2.8 2.3 2 0 0 2 2 2 2 Major Facilitator Superfamily zf-DHHC PF01529.15 CBZ53223.1 - 2.8e-19 69.1 0.7 2.8e-19 69.1 0.5 2.3 2 1 0 2 2 2 1 DHHC palmitoyltransferase DUF4131 PF13567.1 CBZ53223.1 - 0.038 13.3 0.1 0.082 12.3 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) Form_Nir_trans PF01226.12 CBZ53224.1 - 4.7e-75 251.7 16.5 5.7e-75 251.4 11.4 1.1 1 0 0 1 1 1 1 Formate/nitrite transporter TrbC PF04956.8 CBZ53224.1 - 0.26 11.3 5.2 0.13 12.2 1.3 2.3 2 1 0 2 2 2 0 TrbC/VIRB2 family HEAT PF02985.17 CBZ53225.1 - 7e-14 50.5 8.0 0.0043 17.0 0.0 9.8 10 0 0 10 10 10 2 HEAT repeat HEAT_2 PF13646.1 CBZ53225.1 - 1.2e-12 47.9 0.4 1.3e-06 28.6 0.0 9.4 6 3 4 11 11 11 4 HEAT repeats Vac14_Fab1_bd PF12755.2 CBZ53225.1 - 2.3e-10 40.7 7.3 0.39 11.1 0.0 8.5 6 2 3 9 9 9 2 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.1 CBZ53225.1 - 4.4e-08 33.3 23.3 6.6e-05 23.2 0.0 9.3 9 1 1 10 10 10 3 HEAT-like repeat Arm PF00514.18 CBZ53225.1 - 0.00011 21.8 2.6 14 5.6 0.0 6.4 6 0 0 6 6 6 1 Armadillo/beta-catenin-like repeat IBN_N PF03810.14 CBZ53225.1 - 0.00013 21.7 0.5 0.0018 18.1 0.2 3.3 2 1 0 2 2 2 1 Importin-beta N-terminal domain DUF2454 PF10521.4 CBZ53225.1 - 0.0027 16.7 0.1 0.1 11.6 0.0 3.5 4 0 0 4 4 4 1 Protein of unknown function (DUF2454) AAA_25 PF13481.1 CBZ53225.1 - 0.043 13.1 0.1 0.51 9.7 0.0 2.9 2 1 0 2 2 2 0 AAA domain DUF3385 PF11865.3 CBZ53225.1 - 0.06 13.2 0.7 32 4.3 0.0 4.5 4 1 1 5 5 5 0 Domain of unknown function (DUF3385) Cyclin_C PF02984.14 CBZ53226.1 - 1.7e-06 27.9 0.0 4.9e-06 26.4 0.0 1.8 1 0 0 1 1 1 1 Cyclin, C-terminal domain LRR_9 PF14580.1 CBZ53227.1 - 1e-41 142.4 0.1 4.9e-22 78.3 0.0 2.1 1 1 1 2 2 2 2 Leucine-rich repeat LRR_4 PF12799.2 CBZ53227.1 - 0.00018 21.0 5.4 0.024 14.2 0.0 3.1 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) Ribosomal_L28e PF01778.12 CBZ53230.1 - 6.7e-28 97.4 2.2 7.6e-28 97.2 1.6 1.0 1 0 0 1 1 1 1 Ribosomal L28e protein family Ldh_1_N PF00056.18 CBZ53231.1 - 4.2 7.1 0.1 7.7 6.3 0.0 1.3 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain Kelch_4 PF13418.1 CBZ53234.1 - 2.1e-29 101.0 2.7 3.8e-10 39.3 0.0 5.7 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_3 PF13415.1 CBZ53234.1 - 1.2e-24 85.7 6.2 6e-06 26.2 0.0 7.5 7 0 0 7 7 7 5 Galactose oxidase, central domain Kelch_6 PF13964.1 CBZ53234.1 - 8.3e-22 76.3 1.2 6.2e-07 29.3 0.2 5.3 4 1 1 5 5 5 3 Kelch motif DUF4110 PF13422.1 CBZ53234.1 - 3.1e-19 68.6 2.6 3.1e-19 68.6 1.8 3.9 4 0 0 4 4 4 1 Domain of unknown function (DUF4110) Kelch_5 PF13854.1 CBZ53234.1 - 5.5e-18 64.5 0.2 0.0084 16.0 0.0 6.3 6 0 0 6 6 6 4 Kelch motif Kelch_2 PF07646.10 CBZ53234.1 - 3.9e-11 42.2 11.2 3.3e-06 26.6 0.0 5.3 5 1 0 5 5 5 2 Kelch motif Kelch_1 PF01344.20 CBZ53234.1 - 4.1e-11 42.2 2.1 0.03 13.8 0.0 4.9 4 1 0 4 4 4 3 Kelch motif PPO1_DWL PF12142.3 CBZ53234.1 - 0.011 15.2 0.8 0.024 14.1 0.5 1.5 1 0 0 1 1 1 0 Polyphenol oxidase middle domain Glycos_transf_2 PF00535.21 CBZ53234.1 - 0.12 12.0 0.0 0.27 10.9 0.0 1.6 1 0 0 1 1 1 0 Glycosyl transferase family 2 Med14 PF08638.6 CBZ53236.1 - 0.094 11.9 0.0 0.16 11.2 0.0 1.2 1 0 0 1 1 1 0 Mediator complex subunit MED14 MPP6 PF10175.4 CBZ53236.1 - 0.25 11.7 0.0 0.61 10.4 0.0 1.6 1 0 0 1 1 1 0 M-phase phosphoprotein 6 Intg_mem_TP0381 PF09529.5 CBZ53236.1 - 3.2 6.9 1.9 5.8 6.1 1.3 1.3 1 0 0 1 1 1 0 Integral membrane protein (intg_mem_TP0381) Hex_IIIa PF02455.11 CBZ53236.1 - 6.6 5.3 0.6 14 4.2 0.0 1.7 2 0 0 2 2 2 0 Hexon-associated protein (IIIa) Hydrolase_3 PF08282.7 CBZ53237.1 - 5.9e-48 163.6 0.0 7.4e-48 163.3 0.0 1.0 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.8 CBZ53237.1 - 7.5e-10 38.5 0.0 2.7e-09 36.6 0.0 1.8 2 0 0 2 2 2 1 Sucrose-6F-phosphate phosphohydrolase Hydrolase PF00702.21 CBZ53237.1 - 0.0058 17.0 0.3 0.028 14.8 0.2 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 CBZ53237.1 - 0.0087 16.2 0.1 0.042 14.0 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase PhnG PF06754.7 CBZ53237.1 - 0.048 13.2 0.1 0.072 12.7 0.0 1.3 1 0 0 1 1 1 0 Phosphonate metabolism protein PhnG Hydrolase_3 PF08282.7 CBZ53238.1 - 1.5e-48 165.5 0.0 1.9e-48 165.2 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.8 CBZ53238.1 - 1.6e-14 53.8 0.0 4.3e-11 42.5 0.0 2.2 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase Hydrolase PF00702.21 CBZ53238.1 - 0.059 13.7 0.0 10 6.4 0.0 2.5 2 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase RAP PF08373.5 CBZ53239.1 - 0.00061 19.5 0.0 0.0012 18.5 0.0 1.5 1 0 0 1 1 1 1 RAP domain HEAT PF02985.17 CBZ53240.1 - 3.6e-12 45.2 13.2 0.013 15.5 0.0 7.6 8 0 0 8 8 8 4 HEAT repeat HEAT_2 PF13646.1 CBZ53240.1 - 2.5e-11 43.7 11.5 0.00033 20.8 0.4 4.0 3 1 1 4 4 4 4 HEAT repeats DUF2435 PF10363.4 CBZ53240.1 - 0.033 14.0 0.3 5.4 6.9 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2435) Adaptin_N PF01602.15 CBZ53240.1 - 0.087 11.1 0.1 1.7 6.8 0.0 2.2 2 0 0 2 2 2 0 Adaptin N terminal region HEAT_EZ PF13513.1 CBZ53240.1 - 0.13 12.7 17.0 15 6.2 0.1 5.8 5 0 0 5 5 5 0 HEAT-like repeat Transaldolase PF00923.14 CBZ53242.1 - 2.7e-96 322.0 0.5 3.4e-96 321.7 0.3 1.1 1 0 0 1 1 1 1 Transaldolase DUF3633 PF12315.3 CBZ53245.1 - 7.7e-09 35.1 0.1 1.9e-08 33.8 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3633) LIM PF00412.17 CBZ53245.1 - 1.7e-06 27.9 29.0 0.0049 16.9 0.0 5.9 5 1 1 6 6 6 3 LIM domain PDEase_I PF00233.14 CBZ53246.1 - 1.5e-27 96.8 0.3 9.6e-21 74.6 0.5 2.2 1 1 1 2 2 2 2 3'5'-cyclic nucleotide phosphodiesterase Cytochrom_C PF00034.16 CBZ53247.1 - 2.1e-08 34.8 0.0 3.8e-08 34.0 0.0 1.4 1 1 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.1 CBZ53247.1 - 9e-05 22.5 0.6 0.00032 20.7 0.4 2.0 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.1 CBZ53247.1 - 0.0012 18.3 0.0 0.044 13.2 0.0 2.3 2 0 0 2 2 2 1 Cytochrome c-550 domain Cytochrom_C1 PF02167.10 CBZ53247.1 - 0.055 13.1 0.1 0.1 12.2 0.1 1.3 1 0 0 1 1 1 0 Cytochrome C1 family Enkurin PF13864.1 CBZ53252.1 - 0.11 12.7 0.6 0.18 12.0 0.4 1.3 1 0 0 1 1 1 0 Calmodulin-binding SNF2_N PF00176.18 CBZ53253.1 - 2e-48 164.7 1.0 1.3e-40 139.0 0.0 2.5 3 0 0 3 3 3 2 SNF2 family N-terminal domain Helicase_C PF00271.26 CBZ53253.1 - 2.2e-11 43.4 0.0 1e-10 41.3 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 CBZ53253.1 - 4.9e-06 26.4 0.0 2e-05 24.5 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.24 CBZ53253.1 - 3.9e-05 23.2 0.0 8.4e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Feld-I_B PF09252.5 CBZ53253.1 - 0.0079 16.0 0.1 0.021 14.7 0.1 1.6 1 0 0 1 1 1 1 Allergen Fel d I-B chain HDA2-3 PF11496.3 CBZ53253.1 - 0.014 14.1 0.0 0.17 10.6 0.0 2.3 1 1 0 1 1 1 0 Class II histone deacetylase complex subunits 2 and 3 Btz PF09405.5 CBZ53254.1 - 2.6e-11 43.6 2.7 2.6e-11 43.6 1.9 2.9 3 0 0 3 3 3 1 CASC3/Barentsz eIF4AIII binding EF-hand_7 PF13499.1 CBZ53255.1 - 1.1e-26 92.7 12.7 7.7e-10 38.7 0.6 3.4 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.1 CBZ53255.1 - 1.8e-22 77.1 10.2 9.2e-05 22.0 0.0 6.6 5 1 1 6 6 6 5 EF-hand domain EF-hand_1 PF00036.27 CBZ53255.1 - 8.7e-22 74.7 15.9 8.9e-05 21.5 0.2 6.1 6 0 0 6 6 6 5 EF hand EF-hand_5 PF13202.1 CBZ53255.1 - 3.2e-19 67.3 14.8 6.6e-05 22.0 0.0 6.0 6 0 0 6 6 6 4 EF hand SPARC_Ca_bdg PF10591.4 CBZ53255.1 - 1.4e-11 44.4 10.0 8e-05 22.6 0.1 3.3 1 1 2 3 3 3 3 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_8 PF13833.1 CBZ53255.1 - 2.3e-08 33.5 11.5 0.0058 16.2 0.2 5.4 3 2 2 5 5 5 4 EF-hand domain pair Unstab_antitox PF09720.5 CBZ53255.1 - 0.011 15.4 4.9 0.21 11.2 0.1 3.5 3 0 0 3 3 3 0 Putative addiction module component TRCF PF03461.10 CBZ53255.1 - 0.061 13.2 1.7 0.082 12.8 0.1 2.0 3 0 0 3 3 3 0 TRCF domain EF-hand_10 PF14788.1 CBZ53255.1 - 0.27 10.9 4.5 16 5.2 0.0 4.3 3 2 1 4 4 4 0 EF hand TPR_11 PF13414.1 CBZ53256.1 - 5.2e-19 67.6 11.4 1.3e-10 40.8 0.8 2.5 1 1 2 3 3 3 3 TPR repeat TPR_1 PF00515.23 CBZ53256.1 - 2.2e-11 42.8 8.4 1.2e-05 24.7 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 CBZ53256.1 - 1.5e-09 37.0 8.7 6.9e-05 22.4 0.1 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_9 PF13371.1 CBZ53256.1 - 6.4e-05 22.7 1.9 0.00019 21.2 1.3 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.1 CBZ53256.1 - 0.0018 18.7 3.1 0.032 14.8 0.2 3.7 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.1 CBZ53256.1 - 0.0026 17.8 0.1 0.018 15.1 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.1 CBZ53256.1 - 0.007 16.6 1.5 0.021 15.1 0.8 2.1 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_8 PF13181.1 CBZ53256.1 - 0.016 14.9 2.6 0.4 10.5 0.0 3.5 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.1 CBZ53256.1 - 0.016 15.8 0.1 0.016 15.8 0.1 3.6 2 1 0 3 3 2 0 Tetratricopeptide repeat TPR_6 PF13174.1 CBZ53256.1 - 0.018 15.4 1.1 0.13 12.7 0.1 3.1 3 0 0 3 3 2 0 Tetratricopeptide repeat Apc3 PF12895.2 CBZ53256.1 - 0.064 13.3 1.8 0.35 11.0 0.1 2.4 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 CBZ53256.1 - 0.14 12.1 5.5 0.33 10.9 1.0 3.0 2 1 1 3 3 3 0 Tetratricopeptide repeat FAST_1 PF06743.10 CBZ53258.1 - 0.0078 15.9 0.4 12 5.7 0.0 3.4 3 0 0 3 3 3 2 FAST kinase-like protein, subdomain 1 Pkinase PF00069.20 CBZ53259.1 - 2.7e-29 102.1 0.0 3.2e-16 59.2 0.0 3.2 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ53259.1 - 6.3e-14 51.6 0.0 4e-10 39.2 0.0 3.0 3 0 0 3 3 3 2 Protein tyrosine kinase Kdo PF06293.9 CBZ53259.1 - 0.041 12.9 0.0 0.08 11.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Mor PF08765.6 CBZ53259.1 - 0.66 9.7 0.0 1.4 8.7 0.0 1.4 1 0 0 1 1 1 0 Mor transcription activator family Kinase-like PF14531.1 CBZ53259.1 - 1.7 7.5 0.0 5.5 5.8 0.0 1.7 2 0 0 2 2 2 0 Kinase-like DUF1158 PF06643.6 CBZ53259.1 - 1.7 9.0 0.4 3.4 8.0 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1158) Choline_kinase PF01633.15 CBZ53259.1 - 3 7.3 0.0 5 6.6 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase YrbL-PhoP_reg PF10707.4 CBZ53259.1 - 3.1 7.0 0.0 5.8 6.2 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Pox_ser-thr_kin PF05445.6 CBZ53259.1 - 6.3 5.4 0.0 8.8 4.9 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase RIO1 PF01163.17 CBZ53259.1 - 9.4 5.5 0.0 16 4.7 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Antigen_Bd37 PF11641.3 CBZ53260.1 - 0.13 11.5 0.5 0.23 10.6 0.4 1.3 1 0 0 1 1 1 0 Glycosylphosphatidylinositol-anchored merozoite surface protein ATG16 PF08614.6 CBZ53260.1 - 0.48 10.2 13.4 0.07 12.9 6.1 1.9 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) V_ATPase_I PF01496.14 CBZ53260.1 - 1.6 6.5 3.0 2.5 5.8 2.1 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Josephin PF02099.12 CBZ53261.1 - 6.8e-44 149.2 0.0 1.2e-43 148.4 0.0 1.4 1 0 0 1 1 1 1 Josephin UBX PF00789.15 CBZ53261.1 - 2e-06 27.7 0.0 3.5e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 UBX domain UIM PF02809.15 CBZ53261.1 - 0.081 12.5 0.2 0.24 11.0 0.1 1.8 1 0 0 1 1 1 0 Ubiquitin interaction motif Ribosom_S12_S23 PF00164.20 CBZ53262.1 - 2.6e-41 139.8 0.7 3e-41 139.6 0.5 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 ThiF PF00899.16 CBZ53264.1 - 1.1e-19 70.5 0.0 2.2e-19 69.6 0.0 1.4 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.15 CBZ53264.1 - 0.015 15.4 0.0 0.065 13.3 0.0 1.9 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Malic_M PF03949.10 CBZ53264.1 - 0.13 11.7 0.0 0.47 9.9 0.0 1.8 1 1 0 1 1 1 0 Malic enzyme, NAD binding domain OTU PF02338.14 CBZ53265.1 - 1.5e-15 57.8 0.1 3.6e-15 56.6 0.1 1.7 1 0 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.4 CBZ53265.1 - 0.0046 16.3 0.1 2.7 7.2 0.0 2.2 2 0 0 2 2 2 2 Peptidase C65 Otubain RRM_6 PF14259.1 CBZ53267.1 - 0.27 11.2 0.9 3.8 7.5 0.0 3.0 4 0 0 4 4 4 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) FimP PF09766.4 CBZ53268.1 - 2e-07 30.4 2.9 2e-07 30.4 2.0 1.9 2 1 0 2 2 2 1 Fms-interacting protein RRN3 PF05327.6 CBZ53268.1 - 0.25 9.3 4.7 0.079 11.0 0.8 1.9 2 0 0 2 2 2 0 RNA polymerase I specific transcription initiation factor RRN3 DUF2422 PF10337.4 CBZ53268.1 - 0.85 8.3 0.9 1.6 7.4 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2422) Daxx PF03344.10 CBZ53269.1 - 5.7 5.2 11.8 0.67 8.3 3.0 2.1 2 0 0 2 2 2 0 Daxx Family GalKase_gal_bdg PF10509.4 CBZ53270.1 - 9.7e-19 66.3 0.0 1.9e-18 65.4 0.0 1.4 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GLTSCR1 PF15249.1 CBZ53271.1 - 0.085 12.9 0.1 0.21 11.7 0.0 1.6 1 0 0 1 1 1 0 Glioma tumor suppressor candidate region Macro PF01661.16 CBZ53272.1 - 0.00069 19.5 0.0 0.0013 18.6 0.0 1.4 1 0 0 1 1 1 1 Macro domain EF-hand_1 PF00036.27 CBZ53273.1 - 2.9e-17 60.5 2.0 4.3e-05 22.5 0.2 4.2 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.1 CBZ53273.1 - 2.1e-13 48.8 4.0 0.0075 16.0 0.0 4.2 4 0 0 4 4 4 4 EF-hand domain EF-hand_7 PF13499.1 CBZ53273.1 - 7.6e-13 48.4 2.6 7.4e-06 26.0 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 CBZ53273.1 - 5e-10 38.2 0.9 0.00038 19.6 0.0 3.9 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.1 CBZ53273.1 - 5e-08 32.4 2.7 0.00051 19.6 0.0 3.8 1 1 3 4 4 4 2 EF-hand domain pair EF-hand_9 PF14658.1 CBZ53273.1 - 7.8e-06 25.7 0.2 0.038 13.9 0.0 2.7 3 0 0 3 3 3 2 EF-hand domain SPARC_Ca_bdg PF10591.4 CBZ53273.1 - 0.00053 19.9 0.0 0.019 14.9 0.0 2.2 1 1 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region UPF0154 PF03672.8 CBZ53274.1 - 0.79 9.3 2.6 0.54 9.9 0.1 2.0 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0154) p25-alpha PF05517.7 CBZ53276.1 - 3e-36 124.9 2.1 6.5e-36 123.9 1.4 1.6 1 1 0 1 1 1 1 p25-alpha SYF2 PF08231.7 CBZ53277.1 - 2.2e-38 131.7 13.5 2.2e-38 131.7 9.4 3.5 3 2 1 4 4 4 1 SYF2 splicing factor Pro_isomerase PF00160.16 CBZ53277.1 - 1.5e-37 129.1 0.0 5e-37 127.4 0.0 1.9 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD AAA PF00004.24 CBZ53278.1 - 9.2e-45 152.0 0.3 1e-43 148.7 0.0 2.4 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.9 CBZ53278.1 - 3.9e-08 33.3 0.0 9e-08 32.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 CBZ53278.1 - 5.5e-08 32.6 0.2 2.1e-07 30.7 0.1 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 CBZ53278.1 - 3.4e-06 27.2 1.7 0.00025 21.2 0.3 3.0 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 CBZ53278.1 - 2.5e-05 24.3 0.4 0.00011 22.2 0.0 2.2 2 1 0 2 2 2 1 AAA ATPase domain DUF815 PF05673.8 CBZ53278.1 - 3.3e-05 22.9 0.0 9e-05 21.5 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.7 CBZ53278.1 - 4.3e-05 22.6 0.0 0.00018 20.6 0.0 2.0 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_28 PF13521.1 CBZ53278.1 - 0.00018 21.5 0.0 0.00059 19.8 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 CBZ53278.1 - 0.00024 21.9 0.1 0.0014 19.4 0.0 2.2 2 1 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 CBZ53278.1 - 0.00083 18.8 0.0 0.0022 17.4 0.0 1.7 1 0 0 1 1 1 1 IstB-like ATP binding protein NTPase_1 PF03266.10 CBZ53278.1 - 0.00086 19.0 0.1 0.02 14.6 0.0 2.6 3 0 0 3 3 3 1 NTPase AAA_11 PF13086.1 CBZ53278.1 - 0.00095 18.7 0.2 0.038 13.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 CBZ53278.1 - 0.001 18.9 0.1 0.0048 16.7 0.0 1.9 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 CBZ53278.1 - 0.001 19.1 0.0 0.0023 18.0 0.0 1.6 1 0 0 1 1 1 1 RNA helicase Mg_chelatase PF01078.16 CBZ53278.1 - 0.0015 17.7 0.1 0.0035 16.5 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_14 PF13173.1 CBZ53278.1 - 0.0016 18.3 0.0 0.0079 16.0 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_3 PF07726.6 CBZ53278.1 - 0.0017 17.9 0.1 0.04 13.5 0.0 2.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 CBZ53278.1 - 0.0026 17.4 0.6 0.073 12.7 0.0 2.8 2 1 1 3 3 3 1 Archaeal ATPase TIP49 PF06068.8 CBZ53278.1 - 0.0028 16.4 0.0 0.0077 14.9 0.0 1.8 2 0 0 2 2 2 1 TIP49 C-terminus AAA_24 PF13479.1 CBZ53278.1 - 0.0033 17.0 0.2 0.0071 15.9 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 CBZ53278.1 - 0.0037 17.5 0.1 0.019 15.2 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.1 CBZ53278.1 - 0.0043 16.7 0.8 0.013 15.2 0.6 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_25 PF13481.1 CBZ53278.1 - 0.0052 16.2 3.9 0.036 13.4 0.1 2.9 2 1 1 3 3 3 1 AAA domain Zeta_toxin PF06414.7 CBZ53278.1 - 0.0055 15.8 0.0 0.011 14.8 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin NACHT PF05729.7 CBZ53278.1 - 0.0061 16.2 0.3 0.078 12.6 0.1 2.3 2 0 0 2 2 2 1 NACHT domain AAA_23 PF13476.1 CBZ53278.1 - 0.0067 16.7 0.3 2.5 8.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain UPF0079 PF02367.12 CBZ53278.1 - 0.011 15.2 0.0 0.021 14.4 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 Sigma54_activat PF00158.21 CBZ53278.1 - 0.012 15.0 0.0 0.1 12.0 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain Parvo_NS1 PF01057.12 CBZ53278.1 - 0.015 14.2 0.0 0.031 13.1 0.0 1.5 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Sigma54_activ_2 PF14532.1 CBZ53278.1 - 0.017 15.1 0.0 0.076 13.0 0.0 2.1 2 0 0 2 2 2 0 Sigma-54 interaction domain ABC_tran PF00005.22 CBZ53278.1 - 0.037 14.3 0.5 0.39 11.0 0.0 2.8 2 2 0 2 2 2 0 ABC transporter NB-ARC PF00931.17 CBZ53278.1 - 0.04 12.7 0.0 0.08 11.7 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain T2SE PF00437.15 CBZ53278.1 - 0.046 12.6 0.0 0.11 11.4 0.0 1.5 1 1 0 1 1 1 0 Type II/IV secretion system protein KaiC PF06745.8 CBZ53278.1 - 0.05 12.7 1.6 0.62 9.1 0.0 2.6 3 0 0 3 3 3 0 KaiC AAA_30 PF13604.1 CBZ53278.1 - 0.078 12.5 0.0 0.17 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain Torsin PF06309.6 CBZ53278.1 - 0.13 12.1 0.0 0.33 10.8 0.0 1.6 1 0 0 1 1 1 0 Torsin Cpn60_TCP1 PF00118.19 CBZ53279.1 - 4e-143 477.5 8.2 4.6e-143 477.3 5.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Rav1p_C PF12234.3 CBZ53280.1 - 1.3e-23 83.1 1.9 5.4e-21 74.4 0.5 3.0 3 0 0 3 3 3 3 RAVE protein 1 C terminal DUF3654 PF12376.3 CBZ53280.1 - 2.1 8.1 0.0 3.7 7.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3654) Tom22 PF04281.8 CBZ53280.1 - 6.1 6.3 0.6 38 3.7 0.0 2.2 2 0 0 2 2 2 0 Mitochondrial import receptor subunit Tom22 Hanta_nucleocap PF00846.13 CBZ53280.1 - 6.9 5.2 0.0 11 4.5 0.0 1.2 1 0 0 1 1 1 0 Hantavirus nucleocapsid protein TPR_16 PF13432.1 CBZ53281.1 - 4.8e-06 27.0 5.5 0.0019 18.7 1.9 4.9 4 1 2 6 6 6 2 Tetratricopeptide repeat TPR_14 PF13428.1 CBZ53281.1 - 1.2e-05 25.5 19.5 0.0042 17.5 0.3 5.8 4 2 2 6 6 6 3 Tetratricopeptide repeat TPR_17 PF13431.1 CBZ53281.1 - 0.0034 17.4 0.3 0.026 14.7 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.1 CBZ53281.1 - 0.011 15.3 2.4 1.1 8.9 0.1 2.8 2 1 0 2 2 2 0 TPR repeat TPR_19 PF14559.1 CBZ53281.1 - 0.011 16.0 5.6 0.41 11.0 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Suf PF05843.9 CBZ53281.1 - 0.036 13.8 0.0 8.8 5.9 0.0 2.5 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) TPR_2 PF07719.12 CBZ53281.1 - 0.053 13.4 5.3 0.62 10.1 0.3 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.1 CBZ53281.1 - 0.058 13.3 4.7 1.4 8.9 0.2 3.5 2 1 0 3 3 3 0 Tetratricopeptide repeat NRDE-2 PF08424.5 CBZ53281.1 - 0.89 8.3 3.5 3.1 6.5 0.0 2.9 3 1 0 3 3 3 0 NRDE-2, necessary for RNA interference Suf PF05843.9 CBZ53282.1 - 2.3e-12 47.2 0.0 3.5e-11 43.3 0.0 2.2 2 0 0 2 2 2 1 Suppressor of forked protein (Suf) Kinesin PF00225.18 CBZ53283.1 - 2.7e-94 315.6 2.5 3.2e-94 315.3 0.0 2.0 2 0 0 2 2 2 1 Kinesin motor domain BBP1_C PF15272.1 CBZ53283.1 - 0.0099 15.4 0.1 0.0099 15.4 0.1 3.7 4 1 0 4 4 4 1 Spindle pole body component BBP1, C-terminal AAA_22 PF13401.1 CBZ53283.1 - 0.012 15.7 0.1 0.42 10.7 0.0 3.0 2 0 0 2 2 2 0 AAA domain DALR_1 PF05746.10 CBZ53283.1 - 0.045 13.7 1.0 0.087 12.7 0.1 2.0 2 0 0 2 2 2 0 DALR anticodon binding domain AAA_23 PF13476.1 CBZ53283.1 - 6.6 6.9 13.8 6.2 7.0 1.4 3.4 3 1 0 3 3 3 0 AAA domain WD40 PF00400.27 CBZ53284.1 - 2.4e-05 24.0 25.2 0.00022 20.9 0.6 7.0 8 0 0 8 8 8 3 WD domain, G-beta repeat Glycolytic PF00274.14 CBZ53284.1 - 0.28 9.5 0.0 0.45 8.8 0.0 1.2 1 0 0 1 1 1 0 Fructose-bisphosphate aldolase class-I Ribosomal_L3 PF00297.17 CBZ53285.1 - 3.8e-19 69.1 0.4 9.7e-18 64.5 0.3 2.1 1 1 0 1 1 1 1 Ribosomal protein L3 Acetyltransf_1 PF00583.19 CBZ53286.1 - 1.5e-07 31.3 0.1 4e-07 29.9 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 CBZ53286.1 - 0.0066 16.5 0.5 0.063 13.4 0.0 2.5 3 0 0 3 3 3 1 Acetyltransferase (GNAT) domain BolA PF01722.13 CBZ53287.1 - 5.5e-23 80.7 0.0 6.6e-23 80.4 0.0 1.1 1 0 0 1 1 1 1 BolA-like protein DEAD PF00270.24 CBZ53288.1 - 1.3e-13 50.8 0.0 8e-06 25.4 0.0 2.5 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.26 CBZ53288.1 - 1.1e-07 31.5 0.0 2.4e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF106 PF01956.11 CBZ53289.1 - 1.3e-25 89.9 0.3 1.3e-25 89.9 0.2 1.8 1 1 0 2 2 2 1 Integral membrane protein DUF106 CDC27 PF09507.5 CBZ53291.1 - 1.7 7.7 25.1 2 7.5 17.4 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 RR_TM4-6 PF06459.7 CBZ53291.1 - 4.9 6.9 16.0 5.9 6.7 11.1 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 VPS9 PF02204.13 CBZ53293.1 - 2.4e-25 88.5 0.0 4.7e-25 87.6 0.0 1.4 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain ChAPs PF09295.5 CBZ53294.1 - 8.3e-25 87.3 0.1 1.7e-13 50.1 0.0 3.8 4 0 0 4 4 4 3 ChAPs (Chs5p-Arf1p-binding proteins) TPR_17 PF13431.1 CBZ53294.1 - 0.064 13.4 0.0 1.2 9.4 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat RRM_1 PF00076.17 CBZ53295.1 - 0.097 12.3 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TMEM240 PF15207.1 CBZ53298.1 - 0.1 12.1 0.7 0.17 11.4 0.1 1.7 1 1 1 2 2 2 0 TMEM240 family IMCp PF12314.3 CBZ53299.1 - 4.7e-06 26.6 18.1 4.7e-06 26.6 12.5 3.5 1 1 2 3 3 3 3 Inner membrane complex protein VPS11_C PF12451.3 CBZ53300.1 - 2.3e-10 40.1 0.1 5.9e-10 38.8 0.1 1.8 1 0 0 1 1 1 1 Vacuolar protein sorting protein 11 C terminal Clathrin PF00637.15 CBZ53300.1 - 0.00011 21.7 0.7 0.00075 19.1 0.1 2.3 2 1 0 2 2 2 1 Region in Clathrin and VPS zf-RING_2 PF13639.1 CBZ53300.1 - 0.01 15.6 3.9 0.028 14.2 2.7 1.8 1 0 0 1 1 1 1 Ring finger domain SEO_C PF14577.1 CBZ53300.1 - 0.027 13.8 0.1 0.056 12.7 0.1 1.5 1 0 0 1 1 1 0 Sieve element occlusion C-terminus Lin-8 PF03353.10 CBZ53300.1 - 0.032 13.5 2.6 0.059 12.6 1.8 1.4 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Fip1 PF05182.8 CBZ53301.1 - 4.3e-09 35.4 2.0 8.3e-09 34.5 1.4 1.4 1 0 0 1 1 1 1 Fip1 motif EF-hand_8 PF13833.1 CBZ53303.1 - 1.3e-05 24.7 0.3 6.9e-05 22.3 0.0 2.3 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_7 PF13499.1 CBZ53303.1 - 0.034 14.2 0.0 0.096 12.8 0.0 1.8 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_1 PF00036.27 CBZ53303.1 - 0.1 11.9 0.2 0.32 10.4 0.1 1.9 1 0 0 1 1 1 0 EF hand EF-hand_9 PF14658.1 CBZ53303.1 - 0.14 12.0 0.0 0.33 10.8 0.0 1.6 1 0 0 1 1 1 0 EF-hand domain SecE PF00584.15 CBZ53304.1 - 9.6e-13 47.5 0.1 1.1e-12 47.2 0.0 1.1 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex DUF247 PF03140.10 CBZ53305.1 - 1.4 7.8 0.0 2.4 7.0 0.0 1.3 1 0 0 1 1 1 0 Plant protein of unknown function AhpC-TSA PF00578.16 CBZ53306.1 - 2.5e-33 114.4 0.0 3.3e-33 114.0 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 CBZ53306.1 - 3.9e-15 55.6 0.0 5.8e-15 55.1 0.0 1.2 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.4 CBZ53306.1 - 9.2e-08 31.6 0.0 1.6e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin E1-E2_ATPase PF00122.15 CBZ53307.1 - 3.6e-69 232.3 2.0 3.6e-69 232.3 1.4 2.8 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 CBZ53307.1 - 1.5e-47 161.4 2.2 1.5e-47 161.4 1.5 1.8 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 CBZ53307.1 - 8.8e-32 111.2 0.0 5.2e-26 92.4 0.0 2.6 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 CBZ53307.1 - 8.4e-23 80.1 0.0 1.5e-22 79.3 0.0 1.4 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 CBZ53307.1 - 2.1e-19 68.7 0.2 8.1e-19 66.8 0.1 2.1 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 CBZ53307.1 - 4.1e-16 59.7 0.0 1.7e-15 57.7 0.0 2.1 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 CBZ53307.1 - 1.3e-05 24.8 0.5 0.00012 21.8 0.3 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Synaptobrevin PF00957.16 CBZ53308.1 - 3.3e-26 90.7 0.8 4.6e-26 90.2 0.6 1.2 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.1 CBZ53308.1 - 8.1e-19 66.9 0.2 2.1e-18 65.6 0.1 1.7 1 1 1 2 2 2 1 Regulated-SNARE-like domain DUF3675 PF12428.3 CBZ53308.1 - 0.054 13.7 0.1 0.092 13.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3675) Herpes_teg_N PF04843.7 CBZ53308.1 - 0.057 12.8 0.1 0.094 12.1 0.0 1.3 1 0 0 1 1 1 0 Herpesvirus tegument protein, N-terminal conserved region zinc_ribbon_6 PF14599.1 CBZ53309.1 - 1.5e-22 79.1 0.0 1.5e-22 79.1 0.0 4.4 3 2 2 5 5 5 1 Zinc-ribbon zf-CHY PF05495.7 CBZ53309.1 - 2.8e-15 56.1 19.5 2.8e-15 56.1 13.5 3.5 3 1 0 3 3 3 1 CHY zinc finger MIP-T3 PF10243.4 CBZ53309.1 - 8.5 4.7 19.7 11 4.2 13.6 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 GMP_synt_C PF00958.17 CBZ53310.1 - 2e-37 126.7 0.1 4.5e-37 125.6 0.1 1.6 1 0 0 1 1 1 1 GMP synthase C terminal domain GATase PF00117.23 CBZ53310.1 - 9.4e-35 119.8 0.0 1.5e-34 119.1 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 CBZ53310.1 - 6.4e-08 32.3 0.0 1.1e-07 31.5 0.0 1.4 1 0 0 1 1 1 1 Peptidase C26 NAD_synthase PF02540.12 CBZ53310.1 - 2.5e-07 29.8 0.1 4.1e-05 22.6 0.0 2.4 2 0 0 2 2 2 2 NAD synthase Asn_synthase PF00733.16 CBZ53310.1 - 0.001 18.6 0.0 0.002 17.6 0.0 1.4 1 0 0 1 1 1 1 Asparagine synthase tRNA_Me_trans PF03054.11 CBZ53310.1 - 0.0036 15.9 0.3 0.01 14.4 0.1 1.7 2 0 0 2 2 2 1 tRNA methyl transferase QueC PF06508.8 CBZ53310.1 - 0.0079 15.4 0.0 3.2 6.9 0.0 2.5 1 1 0 2 2 2 2 Queuosine biosynthesis protein QueC ADK PF00406.17 CBZ53311.1 - 2.6e-06 27.3 0.0 0.011 15.6 0.0 2.7 2 0 0 2 2 2 2 Adenylate kinase AAA_17 PF13207.1 CBZ53311.1 - 3.2e-05 24.7 0.1 0.00014 22.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 CBZ53311.1 - 0.00077 19.4 0.0 0.0027 17.7 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain DUF1510 PF07423.6 CBZ53311.1 - 0.0013 18.1 10.9 0.0035 16.7 7.6 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) AAA_18 PF13238.1 CBZ53311.1 - 0.0014 18.9 1.6 0.0019 18.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain SDA1 PF05285.7 CBZ53311.1 - 0.002 17.5 14.6 0.0042 16.4 10.2 1.5 1 0 0 1 1 1 1 SDA1 AAA PF00004.24 CBZ53311.1 - 0.011 15.9 0.1 0.032 14.4 0.0 1.8 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.7 CBZ53311.1 - 0.014 14.5 0.1 0.061 12.4 0.0 2.0 2 0 0 2 2 2 0 Zeta toxin Glyco_hydro_4 PF02056.11 CBZ53311.1 - 0.017 14.4 0.0 0.033 13.4 0.0 1.4 1 0 0 1 1 1 0 Family 4 glycosyl hydrolase AAA_5 PF07728.9 CBZ53311.1 - 0.02 14.5 0.1 0.049 13.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 CBZ53311.1 - 0.022 14.6 0.0 0.054 13.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain T2SE PF00437.15 CBZ53311.1 - 0.028 13.3 0.0 0.099 11.5 0.0 1.9 2 0 0 2 2 2 0 Type II/IV secretion system protein CDC45 PF02724.9 CBZ53311.1 - 0.028 12.4 8.0 0.05 11.6 5.6 1.5 1 0 0 1 1 1 0 CDC45-like protein AAA_22 PF13401.1 CBZ53311.1 - 0.071 13.2 0.2 0.35 11.0 0.0 2.2 3 0 0 3 3 2 0 AAA domain Mg_chelatase PF01078.16 CBZ53311.1 - 0.11 11.6 0.0 0.2 10.8 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Raftlin PF15250.1 CBZ53311.1 - 0.12 10.9 1.4 0.19 10.1 0.9 1.2 1 0 0 1 1 1 0 Raftlin Nop14 PF04147.7 CBZ53311.1 - 0.15 9.9 21.5 0.28 9.0 14.9 1.3 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.5 CBZ53311.1 - 0.42 9.6 18.9 0.92 8.5 13.1 1.5 1 0 0 1 1 1 0 BUD22 Daxx PF03344.10 CBZ53311.1 - 2.8 6.3 15.4 5 5.4 10.7 1.3 1 0 0 1 1 1 0 Daxx Family Pkinase PF00069.20 CBZ53312.1 - 1.8e-22 79.7 0.0 1.4e-21 76.8 0.0 1.9 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ53312.1 - 5.7e-10 38.7 0.0 1.4e-09 37.4 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBZ53312.1 - 1.4e-05 24.2 0.0 2.1e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 CBZ53312.1 - 0.0016 17.8 0.0 0.0023 17.3 0.0 1.2 1 0 0 1 1 1 1 RIO1 family APH PF01636.18 CBZ53312.1 - 0.039 13.6 0.0 0.065 12.9 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family WaaY PF06176.6 CBZ53312.1 - 0.098 11.8 0.0 0.14 11.3 0.0 1.1 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) Kdo PF06293.9 CBZ53312.1 - 0.13 11.3 0.0 0.18 10.8 0.0 1.1 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Tox-MPTase4 PF15640.1 CBZ53312.1 - 0.13 11.9 0.0 0.2 11.2 0.0 1.2 1 0 0 1 1 1 0 Metallopeptidase toxin 4 PIP5K PF01504.13 CBZ53314.1 - 1.2e-65 221.1 0.0 1.8e-65 220.5 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase EF-hand_1 PF00036.27 CBZ53314.1 - 0.00047 19.2 0.0 0.0012 17.9 0.0 1.8 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.1 CBZ53314.1 - 0.00081 19.4 0.0 0.0029 17.7 0.0 2.0 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.1 CBZ53314.1 - 0.0023 17.4 0.3 0.0064 16.0 0.2 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 CBZ53314.1 - 0.0027 17.4 0.0 0.011 15.5 0.0 2.1 1 0 0 1 1 1 1 EF-hand domain EF-hand_5 PF13202.1 CBZ53314.1 - 0.02 14.1 0.1 0.062 12.6 0.0 1.9 1 0 0 1 1 1 0 EF hand NADPH_Ox PF08414.5 CBZ53314.1 - 0.057 13.4 0.0 0.24 11.4 0.0 2.0 2 0 0 2 2 2 0 Respiratory burst NADPH oxidase Sigma70_ner PF04546.8 CBZ53314.1 - 8 6.0 8.9 5.7 6.4 0.1 3.1 3 0 0 3 3 3 0 Sigma-70, non-essential region PTCRA PF15028.1 CBZ53316.1 - 0.00089 18.8 0.1 0.0018 17.8 0.0 1.5 1 0 0 1 1 1 1 Pre-T-cell antigen receptor Pro_isomerase PF00160.16 CBZ53317.1 - 5.6e-45 153.3 0.2 6.3e-45 153.1 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD SpoVR PF04293.8 CBZ53318.1 - 0.087 11.1 0.0 0.099 10.9 0.0 1.0 1 0 0 1 1 1 0 SpoVR like protein Guanylate_cyc PF00211.15 CBZ53320.1 - 1.9e-16 59.9 0.0 3.7e-16 59.0 0.0 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain MFS_1 PF07690.11 CBZ53321.1 - 3.2e-25 88.6 27.4 8.1e-14 51.0 1.8 3.1 3 0 0 3 3 3 3 Major Facilitator Superfamily OATP PF03137.15 CBZ53321.1 - 1.7e-11 42.8 5.3 2.8e-06 25.6 0.1 3.2 2 1 1 3 3 3 3 Organic Anion Transporter Polypeptide (OATP) family Sugar_tr PF00083.19 CBZ53321.1 - 5.7e-10 38.3 8.8 2.5e-08 32.9 0.1 3.1 3 0 0 3 3 3 3 Sugar (and other) transporter D123 PF07065.9 CBZ53322.1 - 5.2e-31 107.8 0.0 2.1e-19 69.6 0.0 3.5 3 2 0 3 3 3 2 D123 Glyco_trans_1_4 PF13692.1 CBZ53323.1 - 7.7e-12 45.5 0.2 7.7e-11 42.2 0.1 2.3 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.15 CBZ53323.1 - 0.098 12.0 0.0 0.2 11.0 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 CBZ53323.1 - 0.15 12.3 0.0 0.32 11.2 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferases group 1 MYCBPAP PF14646.1 CBZ53324.1 - 0.012 14.3 0.1 0.4 9.3 0.1 2.3 2 0 0 2 2 2 0 MYCBP-associated protein family DUF778 PF05608.7 CBZ53325.1 - 6.1e-20 71.5 0.5 4.8e-19 68.6 0.3 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF778) Peptidase_C97 PF05903.9 CBZ53325.1 - 0.018 14.8 0.0 0.018 14.8 0.0 1.2 1 0 0 1 1 1 0 PPPDE putative peptidase domain Cytochrom_CIII PF02085.11 CBZ53325.1 - 0.05 13.7 2.2 0.058 13.4 1.5 1.1 1 0 0 1 1 1 0 Class III cytochrome C family HrpB2 PF09487.5 CBZ53325.1 - 0.15 12.2 0.0 0.18 11.9 0.0 1.1 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB2) FAST_1 PF06743.10 CBZ53326.1 - 0.00044 19.9 0.1 0.01 15.5 0.0 3.0 3 0 0 3 3 3 1 FAST kinase-like protein, subdomain 1 Oxidored-like PF09791.4 CBZ53327.1 - 3.3 7.2 5.6 12 5.4 3.9 1.9 1 1 0 1 1 1 0 Oxidoreductase-like protein, N-terminal DUF2362 PF10154.4 CBZ53328.1 - 8.2e-15 54.4 0.0 3.1e-08 32.7 0.0 2.5 3 0 0 3 3 3 2 Uncharacterized conserved protein (DUF2362) TTL PF03133.10 CBZ53330.1 - 9.7e-77 257.7 0.0 1.6e-76 257.0 0.0 1.3 1 1 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.1 CBZ53330.1 - 5e-07 28.7 0.1 0.00012 20.9 0.0 2.6 3 0 0 3 3 3 2 YheC/D like ATP-grasp RimK PF08443.6 CBZ53330.1 - 0.0096 15.4 0.0 1.2 8.6 0.0 2.2 2 0 0 2 2 2 2 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.9 CBZ53330.1 - 0.022 14.6 0.0 2.8 7.8 0.0 2.6 3 0 0 3 3 3 0 ATP-grasp domain ATPgrasp_ST PF14397.1 CBZ53330.1 - 0.028 13.5 0.0 5 6.1 0.0 2.2 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp Nop25 PF09805.4 CBZ53330.1 - 3.5 7.6 8.1 5.3 7.1 5.6 1.2 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) LNS2 PF08235.8 CBZ53332.1 - 4.2e-65 218.1 0.0 6.3e-65 217.5 0.0 1.3 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.9 CBZ53332.1 - 1.3e-28 98.9 0.0 3.7e-28 97.3 0.0 1.7 2 0 0 2 2 2 1 lipin, N-terminal conserved region HAD PF12710.2 CBZ53332.1 - 0.12 12.5 0.0 0.21 11.7 0.0 1.4 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase RINT1_TIP1 PF04437.8 CBZ53333.1 - 0.00055 18.6 0.0 0.0011 17.5 0.0 1.5 1 0 0 1 1 1 1 RINT-1 / TIP-1 family AAA PF00004.24 CBZ53334.1 - 6.7e-61 204.2 0.0 2.6e-41 140.9 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.12 CBZ53334.1 - 3.9e-12 45.9 0.0 7.9e-05 22.1 0.0 2.3 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_16 PF13191.1 CBZ53334.1 - 1.4e-10 41.4 0.1 0.00047 20.2 0.0 3.0 2 1 0 2 2 2 2 AAA ATPase domain AAA_17 PF13207.1 CBZ53334.1 - 1.3e-09 38.9 0.8 0.00068 20.4 0.8 3.3 2 1 0 2 2 2 2 AAA domain AAA_22 PF13401.1 CBZ53334.1 - 1e-08 35.3 0.0 0.0017 18.4 0.0 3.2 2 1 1 3 3 2 2 AAA domain AAA_18 PF13238.1 CBZ53334.1 - 1.6e-08 34.9 0.0 7.8e-05 22.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain RuvB_N PF05496.7 CBZ53334.1 - 5.9e-08 32.0 0.0 0.00013 21.0 0.0 2.6 2 0 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 CBZ53334.1 - 7.3e-08 32.0 0.1 0.015 15.0 0.0 3.3 3 0 0 3 3 3 2 Part of AAA domain AAA_14 PF13173.1 CBZ53334.1 - 1.9e-07 30.9 0.0 0.00039 20.3 0.0 2.8 3 0 0 3 3 2 2 AAA domain AAA_5 PF07728.9 CBZ53334.1 - 2.3e-07 30.6 0.1 0.00047 19.8 0.0 3.2 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) RNA_helicase PF00910.17 CBZ53334.1 - 1.6e-06 28.2 0.0 0.0095 16.0 0.0 2.5 2 0 0 2 2 2 2 RNA helicase TIP49 PF06068.8 CBZ53334.1 - 3.4e-06 26.0 0.0 0.059 12.0 0.0 2.2 2 0 0 2 2 2 2 TIP49 C-terminus NACHT PF05729.7 CBZ53334.1 - 7.6e-06 25.6 0.0 0.18 11.4 0.0 2.9 3 0 0 3 3 3 2 NACHT domain AAA_33 PF13671.1 CBZ53334.1 - 1.7e-05 24.7 0.0 0.0035 17.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 CBZ53334.1 - 2e-05 24.1 1.5 0.067 12.5 0.1 3.4 3 1 0 4 4 3 2 AAA domain Zeta_toxin PF06414.7 CBZ53334.1 - 7e-05 22.0 0.0 0.00096 18.2 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin AAA_28 PF13521.1 CBZ53334.1 - 8.1e-05 22.6 0.3 0.0086 16.0 0.0 2.8 3 0 0 3 3 2 1 AAA domain PhoH PF02562.11 CBZ53334.1 - 0.00013 21.2 0.1 0.34 10.1 0.0 2.2 2 0 0 2 2 2 2 PhoH-like protein AAA_24 PF13479.1 CBZ53334.1 - 0.00016 21.2 0.2 0.062 12.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.16 CBZ53334.1 - 0.00023 20.4 0.1 0.044 12.9 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI ABC_tran PF00005.22 CBZ53334.1 - 0.00029 21.1 0.1 0.65 10.2 0.0 3.1 3 0 0 3 3 3 1 ABC transporter AAA_30 PF13604.1 CBZ53334.1 - 0.0012 18.4 0.2 1.1 8.8 0.0 3.3 3 0 0 3 3 3 1 AAA domain Parvo_NS1 PF01057.12 CBZ53334.1 - 0.0028 16.5 0.0 0.17 10.7 0.0 2.1 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 NB-ARC PF00931.17 CBZ53334.1 - 0.0034 16.3 0.0 1.7 7.4 0.0 2.2 2 0 0 2 2 2 2 NB-ARC domain Viral_helicase1 PF01443.13 CBZ53334.1 - 0.0043 16.5 0.0 0.21 11.0 0.0 2.3 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase Arch_ATPase PF01637.13 CBZ53334.1 - 0.0048 16.6 0.0 0.99 9.0 0.0 2.3 2 0 0 2 2 2 1 Archaeal ATPase AAA_2 PF07724.9 CBZ53334.1 - 0.0088 15.9 0.0 0.041 13.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) ResIII PF04851.10 CBZ53334.1 - 0.0089 15.8 0.0 2.4 7.9 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Bac_DnaA PF00308.13 CBZ53334.1 - 0.01 15.4 0.0 1.7 8.2 0.0 2.4 2 0 0 2 2 2 0 Bacterial dnaA protein Sigma54_activat PF00158.21 CBZ53334.1 - 0.015 14.8 0.0 1.7 8.0 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain NTPase_1 PF03266.10 CBZ53334.1 - 0.017 14.8 0.0 1.3 8.7 0.0 2.5 2 0 0 2 2 2 0 NTPase UPF0079 PF02367.12 CBZ53334.1 - 0.019 14.5 0.1 0.7 9.5 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 Sigma54_activ_2 PF14532.1 CBZ53334.1 - 0.031 14.3 0.1 0.36 10.8 0.0 2.5 3 0 0 3 3 2 0 Sigma-54 interaction domain DAP3 PF10236.4 CBZ53334.1 - 0.095 11.6 0.0 0.54 9.1 0.0 2.0 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 AAA_3 PF07726.6 CBZ53334.1 - 0.1 12.2 0.0 0.48 10.0 0.0 1.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_21 PF13304.1 CBZ53334.1 - 0.18 11.7 0.0 0.31 10.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.10 CBZ53334.1 - 0.28 9.7 0.0 0.46 9.1 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein KaiC PF06745.8 CBZ53334.1 - 0.43 9.6 0.1 2.9 6.9 0.0 2.0 2 0 0 2 2 2 0 KaiC CDC50 PF03381.10 CBZ53335.1 - 6.2e-42 143.6 0.0 8.9e-42 143.1 0.0 1.2 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family SNARE_assoc PF09335.6 CBZ53335.1 - 0.017 15.2 1.2 0.095 12.9 0.1 2.4 3 0 0 3 3 3 0 SNARE associated Golgi protein Dynein_heavy PF03028.10 CBZ53336.1 - 1.4e-175 585.3 0.0 4.3e-175 583.7 0.0 1.9 2 0 0 2 2 2 1 Dynein heavy chain and region D6 of dynein motor DHC_N2 PF08393.8 CBZ53336.1 - 5.2e-87 291.9 0.0 1.7e-83 280.4 0.0 2.8 3 0 0 3 3 3 2 Dynein heavy chain, N-terminal region 2 AAA_6 PF12774.2 CBZ53336.1 - 7.7e-83 277.5 0.0 1.6e-82 276.5 0.0 1.4 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region D1 AAA_8 PF12780.2 CBZ53336.1 - 1.4e-44 152.1 0.0 4e-25 88.3 0.0 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region D4 MT PF12777.2 CBZ53336.1 - 8e-42 143.2 7.9 1.6e-41 142.2 5.5 1.5 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_9 PF12781.2 CBZ53336.1 - 8.5e-33 113.1 0.0 3.9e-24 84.7 0.0 2.4 2 0 0 2 2 2 2 ATP-binding dynein motor region D5 AAA_7 PF12775.2 CBZ53336.1 - 2.8e-22 79.0 0.0 4.8e-12 45.5 0.0 2.7 3 0 0 3 3 3 2 P-loop containing dynein motor region D3 AAA_5 PF07728.9 CBZ53336.1 - 6.4e-16 58.3 0.0 0.0079 15.9 0.0 6.8 5 1 0 5 5 5 4 AAA domain (dynein-related subfamily) AAA PF00004.24 CBZ53336.1 - 6.5e-10 39.3 0.1 0.036 14.2 0.0 5.3 5 0 0 5 5 5 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 CBZ53336.1 - 4.6e-07 30.0 1.8 0.086 12.9 0.0 5.0 5 0 0 5 5 3 2 AAA domain AAA_17 PF13207.1 CBZ53336.1 - 0.00013 22.7 0.0 0.17 12.6 0.0 3.2 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 CBZ53336.1 - 0.00041 20.0 9.7 0.1 12.3 0.1 5.0 5 0 0 5 5 4 2 Part of AAA domain AAA_28 PF13521.1 CBZ53336.1 - 0.0019 18.1 6.6 0.43 10.5 0.1 4.0 3 0 0 3 3 2 2 AAA domain RNA_helicase PF00910.17 CBZ53336.1 - 0.003 17.6 0.1 15 5.7 0.0 3.5 3 0 0 3 3 3 0 RNA helicase AAA_18 PF13238.1 CBZ53336.1 - 0.013 15.7 0.0 12 6.2 0.0 3.0 2 0 0 2 2 2 0 AAA domain Miro PF08477.8 CBZ53336.1 - 0.092 13.2 0.1 1.1 9.8 0.0 2.7 2 0 0 2 2 2 0 Miro-like protein DUF3829 PF12889.2 CBZ53336.1 - 0.2 10.8 2.6 0.71 9.0 1.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3829) MobB PF03205.9 CBZ53336.1 - 1.6 8.4 0.5 28 4.3 0.0 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B IIGP PF05049.8 CBZ53336.1 - 1.6 7.4 1.6 1.6 7.5 0.0 1.7 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) ATP_bind_1 PF03029.12 CBZ53336.1 - 2.2 7.7 6.8 6.9 6.1 0.0 4.3 4 0 0 4 4 4 0 Conserved hypothetical ATP binding protein Endonuc-PvuII PF09225.5 CBZ53336.1 - 4.4 6.9 0.0 73 3.0 0.0 2.2 2 0 0 2 2 2 0 Restriction endonuclease PvuII PyocinActivator PF11112.3 CBZ53338.1 - 0.17 11.7 0.0 1 9.2 0.0 2.1 2 0 0 2 2 2 0 Pyocin activator protein PrtN APG5 PF04106.7 CBZ53339.1 - 1.5e-14 53.9 0.0 1.8e-06 27.5 0.0 3.6 3 2 0 3 3 3 3 Autophagy protein Apg5 PHD PF00628.24 CBZ53341.1 - 8.3e-09 35.0 12.0 2.2e-08 33.6 8.3 1.8 1 0 0 1 1 1 1 PHD-finger MIP-T3 PF10243.4 CBZ53341.1 - 2.9 6.2 22.3 4.1 5.7 15.4 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Abhydrolase_6 PF12697.2 CBZ53342.1 - 1.6e-11 44.5 0.3 1.6e-11 44.5 0.2 2.9 3 0 0 3 3 3 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CBZ53342.1 - 2.7e-06 27.1 0.0 5.3e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 CBZ53342.1 - 5.1e-05 23.0 0.1 0.00013 21.7 0.0 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family Ser_hydrolase PF06821.8 CBZ53342.1 - 0.00038 20.0 0.4 0.00069 19.2 0.2 1.3 1 0 0 1 1 1 1 Serine hydrolase DUF2305 PF10230.4 CBZ53342.1 - 0.0021 17.5 0.1 0.0034 16.8 0.1 1.2 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) Thioesterase PF00975.15 CBZ53342.1 - 0.0092 16.2 0.0 0.02 15.1 0.0 1.5 1 0 0 1 1 1 1 Thioesterase domain PGAP1 PF07819.8 CBZ53342.1 - 0.27 10.7 0.0 0.45 10.0 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Adap_comp_sub PF00928.16 CBZ53344.1 - 1.2e-58 198.2 0.0 1.6e-58 197.8 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family MMS1_N PF10433.4 CBZ53347.1 - 2.4e-110 369.0 0.0 3.3e-110 368.6 0.0 1.2 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.10 CBZ53347.1 - 1.1e-84 284.2 0.0 8.5e-83 278.0 0.0 3.1 3 0 0 3 3 3 1 CPSF A subunit region Myosin_head PF00063.16 CBZ53348.1 - 1.1e-170 569.0 0.0 3.6e-170 567.3 0.0 1.8 1 1 0 1 1 1 1 Myosin head (motor domain) IQ PF00612.22 CBZ53348.1 - 0.00094 18.6 9.8 0.0071 15.8 0.6 2.7 2 0 0 2 2 2 2 IQ calmodulin-binding motif AAA_22 PF13401.1 CBZ53348.1 - 0.11 12.5 0.1 0.97 9.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain FAD_syn PF06574.7 CBZ53349.1 - 0.044 13.4 0.3 0.089 12.4 0.2 1.4 1 0 0 1 1 1 0 FAD synthetase START PF01852.14 CBZ53350.1 - 6.1e-21 74.6 1.0 1e-20 73.9 0.1 1.7 2 0 0 2 2 2 1 START domain TOM13 PF08219.6 CBZ53350.1 - 0.038 13.7 0.9 0.069 12.9 0.0 1.9 2 0 0 2 2 2 0 Outer membrane protein TOM13 TF_Zn_Ribbon PF08271.7 CBZ53351.1 - 0.012 14.9 0.1 0.019 14.2 0.1 1.3 1 0 0 1 1 1 0 TFIIB zinc-binding Elf1 PF05129.8 CBZ53351.1 - 0.021 14.4 0.1 0.048 13.3 0.1 1.5 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like Arv1 PF04161.8 CBZ53353.1 - 3.3e-28 99.0 7.0 7.1e-25 88.1 0.1 2.8 3 0 0 3 3 3 2 Arv1-like family RNase_PH PF01138.16 CBZ53354.1 - 5.8e-17 62.2 0.1 1.4e-15 57.7 0.0 2.3 1 1 0 1 1 1 1 3' exoribonuclease family, domain 1 Peptidase_S8 PF00082.17 CBZ53355.1 - 8.7e-51 172.7 7.1 1.2e-50 172.2 4.9 1.1 1 0 0 1 1 1 1 Subtilase family Pkinase PF00069.20 CBZ53356.1 - 7.4e-35 120.3 0.0 1.1e-34 119.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ53356.1 - 1.8e-25 89.5 0.0 7e-25 87.5 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CBZ53356.1 - 0.00011 22.0 0.0 0.0011 18.7 0.0 2.3 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.1 CBZ53356.1 - 0.06 12.2 0.0 0.47 9.3 0.0 2.0 1 1 0 1 1 1 0 Kinase-like Ribosomal_L38e PF01781.13 CBZ53357.1 - 4e-28 96.9 0.3 5e-28 96.6 0.2 1.1 1 0 0 1 1 1 1 Ribosomal L38e protein family Herpes_U34 PF04541.8 CBZ53359.1 - 0.026 13.4 0.0 0.043 12.7 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus virion protein U34 DUF2933 PF11666.3 CBZ53359.1 - 0.035 13.6 0.9 0.096 12.2 0.7 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2933) UCR_Fe-S_N PF10399.4 CBZ53359.1 - 0.045 12.9 0.1 0.15 11.2 0.1 1.9 1 0 0 1 1 1 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal COPI_assoc PF08507.5 CBZ53360.1 - 1e-15 57.5 9.8 1.3e-15 57.3 6.8 1.0 1 0 0 1 1 1 1 COPI associated protein HAP PF03866.8 CBZ53360.1 - 0.035 13.9 2.2 0.035 13.9 1.5 2.1 2 0 0 2 2 2 0 Hydrophobic abundant protein (HAP) DUF4418 PF14387.1 CBZ53360.1 - 2.1 8.1 12.6 2 8.2 4.2 2.3 1 1 0 2 2 2 0 Domain of unknown function (DUF4418) Oxidored_q2 PF00420.19 CBZ53360.1 - 4.5 6.9 10.5 1 9.0 0.1 2.4 2 1 0 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L Ribosomal_S11 PF00411.14 CBZ53361.1 - 1.9e-05 24.7 1.8 2.7e-05 24.3 1.2 1.2 1 0 0 1 1 1 1 Ribosomal protein S11 Ribosomal_L18p PF00861.17 CBZ53361.1 - 4.5e-05 23.6 1.0 9.3e-05 22.6 0.7 1.5 1 1 0 1 1 1 1 Ribosomal L18p/L5e family LHH PF14411.1 CBZ53361.1 - 0.046 13.9 0.1 0.069 13.3 0.0 1.3 1 0 0 1 1 1 0 A nuclease of the HNH/ENDO VII superfamily with conserved LHH Peptidase_M28 PF04389.12 CBZ53363.1 - 3.7e-10 39.8 0.0 7.7e-10 38.7 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M28 AKAP7_NLS PF10469.4 CBZ53363.1 - 0.085 12.5 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 AKAP7 2'5' RNA ligase-like domain Ribosomal_S25 PF03297.10 CBZ53364.1 - 2.9e-37 126.9 5.8 3.8e-34 116.8 0.1 2.0 2 0 0 2 2 2 2 S25 ribosomal protein HTH_24 PF13412.1 CBZ53364.1 - 0.045 13.1 0.1 0.09 12.1 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Fe_dep_repress PF01325.14 CBZ53364.1 - 0.12 12.2 0.0 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain TrmB PF01978.14 CBZ53364.1 - 0.13 12.0 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB GntR PF00392.16 CBZ53364.1 - 0.13 11.7 0.1 0.31 10.5 0.1 1.7 1 1 0 1 1 1 0 Bacterial regulatory proteins, gntR family Lactamase_B_2 PF12706.2 CBZ53365.1 - 2.8e-10 40.0 0.0 2.1e-09 37.1 0.0 2.1 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 CBZ53365.1 - 6.6e-07 29.1 0.0 0.00016 21.3 0.0 2.2 2 0 0 2 2 2 2 Beta-lactamase superfamily domain SMC_N PF02463.14 CBZ53367.1 - 3.3e-64 216.1 24.3 1.8e-63 213.7 16.9 2.7 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 CBZ53367.1 - 3.1e-22 78.7 0.0 1.2e-21 76.8 0.0 2.2 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 CBZ53367.1 - 8.4e-16 58.7 1.3 2.6e-07 30.9 0.0 3.1 3 0 0 3 3 3 2 AAA domain AAA_23 PF13476.1 CBZ53367.1 - 9.1e-09 35.9 27.9 9.1e-09 35.9 19.3 7.3 3 2 1 4 4 4 1 AAA domain AAA_29 PF13555.1 CBZ53367.1 - 9.3e-07 28.2 0.0 1.9e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.1 CBZ53367.1 - 0.004 16.2 0.1 0.004 16.2 0.0 4.1 4 0 0 4 4 4 1 AAA ATPase domain ABC_tran PF00005.22 CBZ53367.1 - 0.015 15.5 0.0 0.015 15.5 0.0 6.0 5 1 0 5 5 5 0 ABC transporter Pkinase PF00069.20 CBZ53368.1 - 6.7e-16 58.2 0.0 4e-15 55.6 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Kinase-like PF14531.1 CBZ53368.1 - 2.1e-10 40.0 0.0 3.3e-10 39.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_Tyr PF07714.12 CBZ53368.1 - 3.8e-07 29.4 0.0 5.2e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CBZ53368.1 - 0.014 15.1 0.0 0.022 14.5 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family PIP49_C PF12260.3 CBZ53368.1 - 0.027 13.8 0.0 0.048 13.0 0.0 1.4 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 RIO1 PF01163.17 CBZ53368.1 - 0.12 11.7 0.0 0.22 10.8 0.0 1.4 1 0 0 1 1 1 0 RIO1 family ArsA_ATPase PF02374.10 CBZ53369.1 - 4.6e-84 282.0 0.1 5.9e-84 281.6 0.1 1.0 1 0 0 1 1 1 1 Anion-transporting ATPase CbiA PF01656.18 CBZ53369.1 - 2.8e-15 56.2 0.0 5.7e-15 55.2 0.0 1.5 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 CBZ53369.1 - 1.3e-08 34.9 0.0 3.2e-08 33.6 0.0 1.7 1 1 0 1 1 1 1 AAA domain Fer4_NifH PF00142.13 CBZ53369.1 - 2.7e-06 26.7 0.0 5.3e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family SRP54 PF00448.17 CBZ53369.1 - 3.4e-05 23.3 0.4 0.002 17.6 0.0 2.2 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_19 PF13245.1 CBZ53369.1 - 0.00033 20.3 0.0 0.00086 19.0 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain T2SE PF00437.15 CBZ53369.1 - 0.0038 16.1 0.1 0.041 12.7 0.0 2.1 2 0 0 2 2 2 1 Type II/IV secretion system protein YhjQ PF06564.7 CBZ53369.1 - 0.0058 16.0 0.0 0.031 13.6 0.0 2.0 1 1 1 2 2 2 1 YhjQ protein IstB_IS21 PF01695.12 CBZ53369.1 - 0.0072 15.7 0.1 0.024 14.0 0.0 1.8 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_25 PF13481.1 CBZ53369.1 - 0.0089 15.4 0.1 0.079 12.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain MipZ PF09140.6 CBZ53369.1 - 0.0091 15.0 0.2 0.039 13.0 0.1 1.9 1 1 1 2 2 2 1 ATPase MipZ NB-ARC PF00931.17 CBZ53369.1 - 0.014 14.2 0.0 0.025 13.4 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA_16 PF13191.1 CBZ53369.1 - 0.019 14.9 0.4 0.13 12.2 0.0 2.3 1 1 0 2 2 2 0 AAA ATPase domain Zeta_toxin PF06414.7 CBZ53369.1 - 0.023 13.8 0.0 0.054 12.5 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin PhoH PF02562.11 CBZ53369.1 - 0.037 13.2 0.0 0.095 11.9 0.0 1.6 2 0 0 2 2 2 0 PhoH-like protein AAA_10 PF12846.2 CBZ53369.1 - 0.099 12.0 0.2 0.2 11.0 0.1 1.8 1 1 0 1 1 1 0 AAA-like domain AAA PF00004.24 CBZ53369.1 - 0.13 12.4 0.1 1.7 8.8 0.0 2.6 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 CBZ53369.1 - 0.15 12.9 0.0 0.39 11.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.12 CBZ53369.1 - 0.16 11.4 1.0 0.84 9.1 0.1 2.1 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Dynamin_N PF00350.18 CBZ53371.1 - 1.4e-14 54.2 0.0 5.8e-14 52.2 0.0 1.9 1 1 0 1 1 1 1 Dynamin family EF-hand_4 PF12763.2 CBZ53371.1 - 6.5e-10 38.6 0.0 2.1e-09 37.0 0.0 1.8 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand MMR_HSR1 PF01926.18 CBZ53371.1 - 1.1e-06 28.5 0.0 5.3e-06 26.3 0.0 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 CBZ53371.1 - 0.0034 16.8 0.0 0.0055 16.1 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain WD40 PF00400.27 CBZ53373.1 - 7.1e-27 92.2 10.2 1.6e-09 37.2 0.3 7.0 7 0 0 7 7 7 4 WD domain, G-beta repeat PQQ_3 PF13570.1 CBZ53373.1 - 0.016 15.4 0.1 3.6 8.0 0.0 3.5 3 0 0 3 3 3 0 PQQ-like domain eIF2A PF08662.6 CBZ53373.1 - 0.025 14.3 0.0 14 5.3 0.0 3.4 4 0 0 4 4 4 0 Eukaryotic translation initiation factor eIF2A PD40 PF07676.7 CBZ53373.1 - 0.027 14.1 0.6 13 5.6 0.1 3.0 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat SIS PF01380.17 CBZ53374.1 - 8.2e-33 112.7 0.0 1.1e-18 67.1 0.0 2.5 2 0 0 2 2 2 2 SIS domain GATase_6 PF13522.1 CBZ53374.1 - 2.4e-21 76.0 0.1 1.4e-20 73.5 0.1 2.1 1 1 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.1 CBZ53374.1 - 5.5e-16 58.4 0.0 3.7e-15 55.7 0.0 2.2 1 1 0 1 1 1 1 Glutamine amidotransferase domain GATase_2 PF00310.16 CBZ53374.1 - 6.2e-16 58.0 0.1 1.7e-13 50.0 0.0 2.2 2 0 0 2 2 2 2 Glutamine amidotransferases class-II GATase_4 PF13230.1 CBZ53374.1 - 1e-06 27.6 0.1 2e-06 26.6 0.1 1.4 1 0 0 1 1 1 1 Glutamine amidotransferases class-II RAP1 PF07218.6 CBZ53374.1 - 4.1 5.3 6.8 6.4 4.7 4.7 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Patatin PF01734.17 CBZ53376.1 - 1.7e-28 100.0 0.7 1.6e-27 96.7 0.5 2.6 1 1 0 1 1 1 1 Patatin-like phospholipase RNA_pol_Rpb4 PF03874.11 CBZ53377.1 - 1.5e-16 60.4 0.2 1.7e-16 60.2 0.2 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb4 Tubulin PF00091.20 CBZ53379.1 - 1.5e-50 171.9 0.0 2.5e-50 171.2 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 CBZ53379.1 - 2.3e-27 95.5 0.1 6.7e-27 94.0 0.0 1.7 2 0 0 2 2 2 1 Tubulin C-terminal domain GED PF02212.13 CBZ53380.1 - 0.0077 16.1 1.3 0.018 14.9 0.9 1.6 1 0 0 1 1 1 1 Dynamin GTPase effector domain DUF3038 PF11237.3 CBZ53380.1 - 0.084 12.6 1.5 0.21 11.3 0.6 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3038) BT1 PF03092.11 CBZ53381.1 - 1.1e-50 172.6 16.4 7.1e-43 146.9 7.3 2.1 1 1 1 2 2 2 2 BT1 family MFS_2 PF13347.1 CBZ53381.1 - 0.0095 14.3 27.4 0.022 13.1 12.9 2.2 1 1 1 2 2 2 2 MFS/sugar transport protein STT3 PF02516.9 CBZ53382.1 - 2.4e-81 274.1 42.2 3.2e-81 273.7 29.3 1.2 1 0 0 1 1 1 1 Oligosaccharyl transferase STT3 subunit LsmAD PF06741.8 CBZ53383.1 - 1.3e-14 54.0 0.1 2.1e-14 53.3 0.0 1.4 1 0 0 1 1 1 1 LsmAD domain SM-ATX PF14438.1 CBZ53383.1 - 5.3e-11 42.2 0.0 9.4e-11 41.4 0.0 1.4 1 0 0 1 1 1 1 Ataxin 2 SM domain ATP-synt_10 PF05176.9 CBZ53384.1 - 0.0035 16.6 0.0 0.0051 16.1 0.0 1.2 1 0 0 1 1 1 1 ATP10 protein HEAT PF02985.17 CBZ53386.1 - 1.1e-15 56.2 56.6 0.00081 19.2 0.0 20.2 22 0 0 22 22 22 5 HEAT repeat Vac14_Fab1_bd PF12755.2 CBZ53386.1 - 5.9e-10 39.4 0.0 1.6 9.1 0.0 7.8 7 1 2 9 9 9 3 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.1 CBZ53386.1 - 2.6e-09 37.2 1.3 0.00045 20.6 0.2 19.8 20 3 5 25 25 25 6 HEAT-like repeat Adaptin_N PF01602.15 CBZ53386.1 - 8.8e-08 30.9 0.9 0.0019 16.6 0.0 4.9 7 0 0 7 7 7 2 Adaptin N terminal region UME PF08064.8 CBZ53386.1 - 1.3e-06 28.2 2.4 0.81 9.6 0.0 6.0 6 0 0 6 6 6 2 UME (NUC010) domain CLASP_N PF12348.3 CBZ53386.1 - 0.00067 19.0 0.3 0.082 12.2 0.0 4.3 5 0 0 5 5 5 1 CLASP N terminal ParcG PF10274.4 CBZ53386.1 - 0.0019 18.1 0.8 1.1e+02 2.6 0.0 6.0 5 1 0 5 5 5 0 Parkin co-regulated protein Proteasom_PSMB PF10508.4 CBZ53386.1 - 0.045 12.0 1.1 0.21 9.8 0.0 2.7 3 0 0 3 3 3 0 Proteasome non-ATPase 26S subunit Ipi1_N PF12333.3 CBZ53386.1 - 0.12 12.3 10.0 2.7 7.9 0.0 7.7 10 0 0 10 10 10 0 Rix1 complex component involved in 60S ribosome maturation Cnd1 PF12717.2 CBZ53386.1 - 0.18 11.6 0.0 1.1e+02 2.6 0.0 4.4 4 1 0 4 4 4 0 non-SMC mitotic condensation complex subunit 1 SGS PF05002.10 CBZ53387.1 - 5.9e-28 96.4 2.7 9.9e-28 95.7 1.9 1.4 1 0 0 1 1 1 1 SGS domain CS PF04969.11 CBZ53387.1 - 3e-05 24.4 0.5 5.4e-05 23.6 0.1 1.6 2 0 0 2 2 2 1 CS domain DUF2057 PF09829.4 CBZ53387.1 - 0.023 14.3 0.5 0.031 13.9 0.4 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2057) HEAT_2 PF13646.1 CBZ53388.1 - 5.4e-16 58.6 28.7 1.4e-07 31.6 0.0 8.9 7 3 2 9 9 9 7 HEAT repeats HEAT PF02985.17 CBZ53388.1 - 5.2e-12 44.7 24.1 0.016 15.2 0.0 10.8 11 0 0 11 11 11 3 HEAT repeat HEAT_EZ PF13513.1 CBZ53388.1 - 7.6e-10 38.9 41.3 0.14 12.7 0.1 13.3 13 2 2 15 15 15 5 HEAT-like repeat RIX1 PF08167.7 CBZ53388.1 - 0.00011 21.9 0.9 1.6 8.4 0.0 4.9 4 2 1 5 5 5 1 rRNA processing/ribosome biogenesis IBN_N PF03810.14 CBZ53388.1 - 0.014 15.3 0.3 0.087 12.7 0.2 2.6 1 0 0 1 1 1 0 Importin-beta N-terminal domain Vac14_Fab1_bd PF12755.2 CBZ53388.1 - 0.041 14.2 1.3 37 4.7 0.1 4.2 3 0 0 3 3 3 0 Vacuolar 14 Fab1-binding region Arm PF00514.18 CBZ53388.1 - 0.061 13.1 19.2 4.5 7.2 0.0 7.1 8 0 0 8 8 8 0 Armadillo/beta-catenin-like repeat GHMP_kinases_N PF00288.21 CBZ53388.1 - 4.5 7.4 11.0 1.6 8.8 0.9 3.7 3 0 0 3 3 3 0 GHMP kinases N terminal domain ATP-gua_Ptrans PF00217.14 CBZ53389.1 - 4.1e-15 55.7 0.0 3.7e-05 23.1 0.0 4.8 3 1 1 4 4 4 4 ATP:guanido phosphotransferase, C-terminal catalytic domain ATP-gua_PtransN PF02807.10 CBZ53389.1 - 0.00011 22.2 0.0 0.096 12.8 0.0 2.6 2 0 0 2 2 2 2 ATP:guanido phosphotransferase, N-terminal domain IMCp PF12314.3 CBZ53390.1 - 2.6e-29 101.2 98.1 3.5e-17 62.3 18.1 4.8 1 1 4 5 5 5 4 Inner membrane complex protein IMCp PF12314.3 CBZ53391.1 - 6.5e-30 103.1 43.6 6.5e-30 103.1 30.2 5.2 2 2 2 4 4 4 2 Inner membrane complex protein AAA_23 PF13476.1 CBZ53391.1 - 0.32 11.2 11.6 0.62 10.3 8.1 1.4 1 0 0 1 1 1 0 AAA domain MAP7 PF05672.6 CBZ53391.1 - 0.35 10.2 22.2 0.97 8.7 15.4 1.8 1 0 0 1 1 1 0 MAP7 (E-MAP-115) family Macro PF01661.16 CBZ53392.1 - 9.4e-09 35.2 0.0 7.9e-06 25.7 0.0 2.4 2 0 0 2 2 2 2 Macro domain Tubulin_C PF03953.12 CBZ53393.1 - 2.2e-46 156.9 0.1 3.2e-46 156.4 0.1 1.2 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin PF00091.20 CBZ53393.1 - 4.6e-33 114.8 0.0 8e-33 114.0 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_3 PF14881.1 CBZ53393.1 - 0.011 15.2 0.0 0.017 14.5 0.0 1.5 1 0 0 1 1 1 0 Tubulin domain DUF1415 PF07209.7 CBZ53393.1 - 0.083 12.6 0.1 1.9 8.2 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1415) Gemini_AL1 PF00799.15 CBZ53395.1 - 0.24 11.2 0.0 0.49 10.2 0.0 1.4 1 0 0 1 1 1 0 Geminivirus Rep catalytic domain Helicase_C_2 PF13307.1 CBZ53396.1 - 4.2e-38 130.9 0.0 9.5e-32 110.2 0.0 2.6 2 0 0 2 2 2 2 Helicase C-terminal domain DEAD_2 PF06733.10 CBZ53396.1 - 3.1e-23 82.0 0.2 7.8e-16 57.9 0.0 2.4 2 0 0 2 2 2 2 DEAD_2 DEAD PF00270.24 CBZ53396.1 - 0.0005 19.5 0.1 0.012 15.1 0.1 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_11 PF13086.1 CBZ53396.1 - 0.00086 18.9 0.1 0.0018 17.8 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 CBZ53396.1 - 0.0015 18.2 1.7 0.0033 17.1 0.1 2.5 2 0 0 2 2 2 1 Part of AAA domain ResIII PF04851.10 CBZ53396.1 - 0.0026 17.6 0.1 0.019 14.7 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit PhoH PF02562.11 CBZ53396.1 - 0.27 10.4 0.1 0.51 9.5 0.1 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_11 PF13086.1 CBZ53397.1 - 6.7e-54 182.9 0.3 1.3e-49 168.9 0.0 3.3 2 1 0 2 2 2 2 AAA domain AAA_12 PF13087.1 CBZ53397.1 - 5.5e-48 163.0 0.0 2.3e-47 160.9 0.0 2.0 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.1 CBZ53397.1 - 2e-12 47.0 1.6 1.2e-07 31.4 0.0 3.1 3 0 0 3 3 3 2 AAA domain AAA_19 PF13245.1 CBZ53397.1 - 1.2e-09 37.8 0.1 1.2e-09 37.8 0.1 3.4 4 0 0 4 4 4 1 Part of AAA domain Viral_helicase1 PF01443.13 CBZ53397.1 - 9.3e-05 22.0 0.0 0.35 10.3 0.0 3.6 4 0 0 4 4 4 2 Viral (Superfamily 1) RNA helicase DEAD PF00270.24 CBZ53397.1 - 0.00051 19.5 0.0 0.001 18.5 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 CBZ53397.1 - 0.16 11.7 0.0 0.38 10.5 0.0 1.7 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit UvrD-helicase PF00580.16 CBZ53397.1 - 0.55 9.4 1.2 48 3.1 0.3 3.0 3 1 0 3 3 3 0 UvrD/REP helicase N-terminal domain Rad17 PF03215.10 CBZ53397.1 - 2 7.0 0.0 3.1 6.3 0.0 1.1 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein DUF3896 PF13035.1 CBZ53398.1 - 4.3 7.4 8.3 0.35 10.9 2.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3896) PP2C PF00481.16 CBZ53399.1 - 1.4e-35 122.8 0.0 2e-35 122.4 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 CBZ53399.1 - 0.00027 20.3 0.0 0.0021 17.5 0.0 2.0 1 1 0 1 1 1 1 Protein phosphatase 2C TPR_11 PF13414.1 CBZ53401.1 - 2.6e-20 71.8 6.4 2.4e-11 43.0 0.1 3.9 2 1 1 3 3 3 3 TPR repeat TPR_1 PF00515.23 CBZ53401.1 - 1.2e-19 68.9 0.7 1.1e-06 27.9 0.0 5.5 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_2 PF07719.12 CBZ53401.1 - 1.4e-19 68.3 5.1 2.4e-05 23.8 0.0 5.9 5 0 0 5 5 5 5 Tetratricopeptide repeat TPR_16 PF13432.1 CBZ53401.1 - 7.6e-15 55.1 18.7 1.4e-07 31.9 0.7 5.3 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 CBZ53401.1 - 7.5e-13 47.8 22.6 0.00029 21.2 0.3 8.1 5 2 3 8 8 7 4 Tetratricopeptide repeat TPR_19 PF14559.1 CBZ53401.1 - 6e-11 42.5 6.7 4.4e-06 26.9 0.6 4.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.1 CBZ53401.1 - 2.5e-10 39.7 7.2 2.9e-05 23.8 0.0 6.1 6 1 0 6 6 6 2 Tetratricopeptide repeat TPR_7 PF13176.1 CBZ53401.1 - 6.2e-10 38.1 4.7 8e-05 22.1 0.0 5.6 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.1 CBZ53401.1 - 2.4e-08 33.1 0.0 0.048 13.4 0.0 5.0 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_12 PF13424.1 CBZ53401.1 - 5.2e-08 32.7 8.1 3.5e-05 23.6 0.4 4.3 3 2 1 4 4 3 2 Tetratricopeptide repeat TPR_9 PF13371.1 CBZ53401.1 - 1.5e-05 24.7 3.1 0.027 14.2 0.1 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.1 CBZ53401.1 - 0.00017 21.3 4.4 0.093 12.6 0.1 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat BTAD PF03704.12 CBZ53401.1 - 0.0012 19.1 10.8 0.0072 16.6 0.1 3.5 3 0 0 3 3 3 2 Bacterial transcriptional activator domain Apc3 PF12895.2 CBZ53401.1 - 0.011 15.8 0.1 1.3 9.1 0.0 2.9 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 CBZ53401.1 - 0.67 10.5 7.5 16 6.2 0.0 5.0 5 1 0 5 5 4 0 Tetratricopeptide repeat TPR_4 PF07721.9 CBZ53401.1 - 0.7 10.4 0.0 0.7 10.4 0.0 5.1 4 0 0 4 4 3 0 Tetratricopeptide repeat ACP_syn_III_C PF08541.5 CBZ53403.1 - 2.7e-38 129.8 0.1 1e-37 128.0 0.0 2.0 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ACP_syn_III PF08545.5 CBZ53403.1 - 3.9e-26 90.5 0.0 1.2e-25 88.9 0.0 1.9 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Chal_sti_synt_C PF02797.10 CBZ53403.1 - 2.3e-05 24.3 0.0 3.8e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Chalcone and stilbene synthases, C-terminal domain Thiolase_C PF02803.13 CBZ53403.1 - 0.019 14.4 0.1 0.28 10.6 0.0 2.6 3 0 0 3 3 3 0 Thiolase, C-terminal domain Acyl-CoA_dh_1 PF00441.19 CBZ53404.1 - 1.6e-15 57.4 1.0 4.8e-14 52.7 0.1 2.3 1 1 1 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 CBZ53404.1 - 2.4e-12 47.4 0.1 4.7e-12 46.4 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_ox_N PF14749.1 CBZ53404.1 - 0.00077 19.7 0.0 0.0012 19.1 0.0 1.3 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal DUF3693 PF12472.3 CBZ53404.1 - 0.11 12.1 0.3 4.4 6.9 0.0 2.6 2 0 0 2 2 2 0 Phage related protein ATP-synt PF00231.14 CBZ53405.1 - 1.3e-75 254.5 0.8 1.5e-75 254.2 0.6 1.1 1 0 0 1 1 1 1 ATP synthase Pox_L3_FP4 PF03339.9 CBZ53405.1 - 0.076 11.4 0.0 0.11 10.9 0.0 1.2 1 0 0 1 1 1 0 Poxvirus L3/FP4 protein CTP-dep_RFKase PF01982.11 CBZ53405.1 - 0.13 11.9 0.0 0.31 10.6 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function DUF120 adh_short PF00106.20 CBZ53406.1 - 0.0085 16.0 0.2 0.02 14.7 0.0 1.7 2 1 0 2 2 2 1 short chain dehydrogenase PLA2_inh PF02988.10 CBZ53406.1 - 0.061 13.7 0.0 19 5.7 0.0 2.3 2 0 0 2 2 2 0 Phospholipase A2 inhibitor ThiF PF00899.16 CBZ53408.1 - 1.2e-35 122.3 0.0 3.8e-35 120.6 0.0 1.8 1 1 0 1 1 1 1 ThiF family Saccharop_dh PF03435.13 CBZ53408.1 - 0.0017 17.3 0.2 1.2 8.0 0.0 2.2 2 0 0 2 2 2 2 Saccharopine dehydrogenase MoeZ_MoeB PF05237.8 CBZ53408.1 - 0.0072 15.9 0.7 0.13 11.9 0.1 2.7 1 1 0 2 2 2 1 MoeZ/MoeB domain NAD_binding_7 PF13241.1 CBZ53408.1 - 0.041 14.1 0.1 0.21 11.8 0.1 2.0 1 1 0 1 1 1 0 Putative NAD(P)-binding UDPG_MGDP_dh_N PF03721.9 CBZ53408.1 - 0.094 12.0 0.1 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain FAD_binding_3 PF01494.14 CBZ53408.1 - 0.12 11.3 0.4 0.18 10.7 0.2 1.2 1 0 0 1 1 1 0 FAD binding domain ECSIT PF06239.6 CBZ53408.1 - 0.15 10.9 0.0 0.32 9.8 0.0 1.5 1 0 0 1 1 1 0 Evolutionarily conserved signalling intermediate in Toll pathway 2-Hacid_dh_C PF02826.14 CBZ53408.1 - 0.16 11.1 0.0 0.26 10.4 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain PROCN PF08083.6 CBZ53410.1 - 4.9e-217 720.2 6.7 7.5e-217 719.6 4.6 1.3 1 0 0 1 1 1 1 PROCN (NUC071) domain PRP8_domainIV PF12134.3 CBZ53410.1 - 2.7e-123 409.7 1.5 4.4e-123 409.0 1.0 1.4 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.4 CBZ53410.1 - 2.7e-92 306.3 1.6 5.1e-92 305.4 1.1 1.5 1 0 0 1 1 1 1 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.6 CBZ53410.1 - 1.1e-82 275.0 3.6 1.1e-82 275.0 2.5 2.2 3 0 0 3 3 3 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.4 CBZ53410.1 - 1.3e-68 228.8 0.1 2.6e-68 227.8 0.1 1.6 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 PROCT PF08084.6 CBZ53410.1 - 3.2e-51 172.2 0.1 6.8e-51 171.2 0.1 1.6 1 0 0 1 1 1 1 PROCT (NUC072) domain RRM_4 PF10598.4 CBZ53410.1 - 1.8e-44 149.5 0.4 5e-44 148.0 0.3 1.8 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 JAB PF01398.16 CBZ53410.1 - 1.4e-07 31.2 0.0 3.1e-07 30.1 0.0 1.6 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease BAF1_ABF1 PF04684.8 CBZ53412.1 - 0.064 12.0 0.0 0.074 11.8 0.0 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor NMO PF03060.10 CBZ53412.1 - 0.12 11.4 0.0 0.12 11.4 0.0 1.1 1 0 0 1 1 1 0 Nitronate monooxygenase PP2C PF00481.16 CBZ53414.1 - 3.2e-50 170.8 0.0 8.3e-26 90.9 0.0 3.5 3 0 0 3 3 3 3 Protein phosphatase 2C GrpE PF01025.14 CBZ53415.1 - 0.081 12.4 2.5 0.14 11.6 1.7 1.3 1 0 0 1 1 1 0 GrpE Fib_alpha PF08702.5 CBZ53416.1 - 0.0001 22.4 1.9 0.00013 22.1 1.3 1.1 1 0 0 1 1 1 1 Fibrinogen alpha/beta chain family RmuC PF02646.11 CBZ53416.1 - 0.001 17.9 4.7 0.0014 17.4 3.2 1.3 1 0 0 1 1 1 1 RmuC family SlyX PF04102.7 CBZ53416.1 - 0.0047 17.2 8.0 0.02 15.2 0.5 2.3 2 0 0 2 2 2 1 SlyX Gp-FAR-1 PF05823.7 CBZ53416.1 - 0.0063 16.4 0.9 0.011 15.7 0.6 1.3 1 0 0 1 1 1 1 Nematode fatty acid retinoid binding protein (Gp-FAR-1) Bacillus_HBL PF05791.6 CBZ53416.1 - 0.0079 15.5 2.5 0.031 13.6 2.4 1.5 2 0 0 2 2 1 1 Bacillus haemolytic enterotoxin (HBL) BicD PF09730.4 CBZ53416.1 - 0.0091 14.4 4.4 0.012 14.0 3.0 1.0 1 0 0 1 1 1 1 Microtubule-associated protein Bicaudal-D TMPIT PF07851.8 CBZ53416.1 - 0.0096 15.0 4.1 0.013 14.6 2.8 1.0 1 0 0 1 1 1 1 TMPIT-like protein IncA PF04156.9 CBZ53416.1 - 0.01 15.4 5.3 0.016 14.7 3.7 1.3 1 0 0 1 1 1 0 IncA protein HCR PF07111.7 CBZ53416.1 - 0.013 13.5 9.2 0.016 13.2 6.4 1.0 1 0 0 1 1 1 0 Alpha helical coiled-coil rod protein (HCR) DUF3584 PF12128.3 CBZ53416.1 - 0.014 12.8 4.0 0.017 12.4 2.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) XRCC4 PF06632.7 CBZ53416.1 - 0.014 14.2 1.1 0.017 13.9 0.8 1.1 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 DUF3847 PF12958.2 CBZ53416.1 - 0.016 14.9 6.4 0.35 10.6 0.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3847) MerR-DNA-bind PF09278.6 CBZ53416.1 - 0.022 15.1 3.7 0.57 10.6 0.4 2.3 2 0 0 2 2 2 0 MerR, DNA binding Hormone_1 PF00103.15 CBZ53416.1 - 0.023 14.0 2.3 0.045 13.1 0.3 1.9 1 1 1 2 2 2 0 Somatotropin hormone family Fmp27_WPPW PF10359.4 CBZ53416.1 - 0.025 13.0 1.4 0.029 12.7 1.0 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain HNF-1_N PF04814.8 CBZ53416.1 - 0.027 14.5 1.8 0.037 14.1 1.3 1.1 1 0 0 1 1 1 0 Hepatocyte nuclear factor 1 (HNF-1), N terminus HisKA_3 PF07730.8 CBZ53416.1 - 0.055 13.8 6.9 1.8 8.9 0.9 2.7 2 1 1 3 3 3 0 Histidine kinase DASH_Dad3 PF08656.5 CBZ53416.1 - 0.06 13.0 2.2 0.23 11.2 0.1 2.3 2 1 0 2 2 2 0 DASH complex subunit Dad3 DUF641 PF04859.7 CBZ53416.1 - 0.079 12.7 6.0 0.26 11.0 4.2 1.8 1 1 0 1 1 1 0 Plant protein of unknown function (DUF641) Cep57_CLD_2 PF14197.1 CBZ53416.1 - 0.095 12.6 6.4 0.81 9.6 0.2 2.6 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 Uso1_p115_C PF04871.8 CBZ53416.1 - 0.12 12.2 7.3 0.28 11.1 5.1 1.5 1 1 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region TMCO5 PF14992.1 CBZ53416.1 - 0.13 11.4 4.2 0.17 10.9 2.9 1.1 1 0 0 1 1 1 0 TMCO5 family DIT1_PvcA PF05141.7 CBZ53416.1 - 0.13 11.5 2.4 0.25 10.6 1.8 1.3 1 1 0 1 1 1 0 Pyoverdine/dityrosine biosynthesis protein Spc7 PF08317.6 CBZ53416.1 - 0.14 10.8 4.9 0.19 10.3 3.4 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein V_ATPase_I PF01496.14 CBZ53416.1 - 0.15 9.8 1.1 0.21 9.3 0.8 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family HXXSHH PF07586.6 CBZ53416.1 - 0.16 10.8 2.1 0.2 10.5 1.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1552) Med9 PF07544.8 CBZ53416.1 - 0.17 11.6 3.1 3 7.6 0.2 2.6 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 TPR_MLP1_2 PF07926.7 CBZ53416.1 - 0.18 11.5 12.0 0.066 12.9 1.4 2.3 1 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein Cep57_MT_bd PF06657.8 CBZ53416.1 - 0.23 11.4 6.9 0.84 9.6 0.6 2.2 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Reo_sigmaC PF04582.7 CBZ53416.1 - 0.23 10.6 1.1 0.5 9.4 0.8 1.5 1 1 0 1 1 1 0 Reovirus sigma C capsid protein DUF342 PF03961.8 CBZ53416.1 - 0.26 9.6 4.1 0.36 9.1 2.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) APG6 PF04111.7 CBZ53416.1 - 0.3 10.0 7.9 0.39 9.7 5.5 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Syntaxin PF00804.20 CBZ53416.1 - 0.32 11.1 8.7 0.74 10.0 6.1 1.5 1 1 0 1 1 1 0 Syntaxin Golgin_A5 PF09787.4 CBZ53416.1 - 0.33 9.4 9.3 3.2 6.1 6.4 1.9 1 1 0 1 1 1 0 Golgin subfamily A member 5 Herpes_UL6 PF01763.11 CBZ53416.1 - 0.37 8.9 2.8 0.42 8.7 1.9 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like EIAV_Rev PF11129.3 CBZ53416.1 - 0.38 10.7 4.3 0.57 10.1 0.3 2.1 1 1 1 2 2 2 0 Rev protein of equine infectious anaemia virus Sec2p PF06428.6 CBZ53416.1 - 0.43 10.4 7.6 4.4 7.2 5.8 2.1 2 1 0 2 2 2 0 GDP/GTP exchange factor Sec2p DivIVA PF05103.8 CBZ53416.1 - 0.44 10.5 8.5 3.4 7.7 1.1 2.3 1 1 1 2 2 2 0 DivIVA protein Mnd1 PF03962.10 CBZ53416.1 - 0.55 9.8 7.3 0.75 9.4 5.0 1.2 1 0 0 1 1 1 0 Mnd1 family Lebercilin PF15619.1 CBZ53416.1 - 0.66 9.3 12.4 7.5 5.9 8.6 2.0 1 1 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease Occludin_ELL PF07303.8 CBZ53416.1 - 0.76 10.5 4.9 2.8 8.7 3.4 2.0 1 1 0 1 1 1 0 Occludin homology domain AAA_23 PF13476.1 CBZ53416.1 - 1.1 9.4 4.8 1.8 8.8 3.3 1.3 1 0 0 1 1 1 0 AAA domain CorA PF01544.13 CBZ53416.1 - 1.2 8.0 3.6 1.1 8.2 0.9 1.6 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein bZIP_1 PF00170.16 CBZ53416.1 - 1.2 9.0 10.1 0.11 12.4 1.7 2.2 2 0 0 2 2 2 0 bZIP transcription factor HemX PF04375.9 CBZ53416.1 - 1.4 7.3 7.6 2 6.9 5.3 1.2 1 0 0 1 1 1 0 HemX COG2 PF06148.6 CBZ53416.1 - 1.5 8.6 7.2 7.9 6.3 0.4 2.1 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Atg14 PF10186.4 CBZ53416.1 - 2 7.3 12.7 5.4 5.8 8.8 1.6 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DASH_Spc34 PF08657.5 CBZ53416.1 - 2.1 7.9 10.4 2.8 7.5 7.0 1.3 1 1 0 1 1 1 0 DASH complex subunit Spc34 DUF3450 PF11932.3 CBZ53416.1 - 2.1 7.5 9.9 8.5 5.5 6.9 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) DUF972 PF06156.8 CBZ53416.1 - 2.3 8.5 9.3 1.7 8.9 2.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Cauli_AT PF03233.8 CBZ53416.1 - 3.1 7.4 5.7 12 5.5 0.7 2.1 1 1 1 2 2 2 0 Aphid transmission protein Kinetocho_Slk19 PF12709.2 CBZ53416.1 - 3.3 7.8 9.5 8.1 6.5 1.5 2.2 1 1 0 2 2 2 0 Central kinetochore-associated DUF4446 PF14584.1 CBZ53416.1 - 3.5 7.4 7.4 8.3 6.2 0.9 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF4446) OmpH PF03938.9 CBZ53416.1 - 3.7 7.4 12.7 10 6.0 8.8 1.6 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF904 PF06005.7 CBZ53416.1 - 3.9 7.8 14.2 1.1e+02 3.1 9.8 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF904) CENP-H PF05837.7 CBZ53416.1 - 6 7.1 8.9 13 6.0 6.1 1.6 1 1 0 1 1 1 0 Centromere protein H (CENP-H) CDC50 PF03381.10 CBZ53417.1 - 1.3e-42 145.9 0.0 1.7e-42 145.5 0.0 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family DnaJ PF00226.26 CBZ53418.1 - 3.9e-15 55.3 0.3 2.1e-14 52.9 0.0 2.2 2 0 0 2 2 2 1 DnaJ domain Thioredoxin_6 PF13848.1 CBZ53418.1 - 0.083 12.6 0.0 0.21 11.3 0.0 1.7 1 0 0 1 1 1 0 Thioredoxin-like domain Peptidase_S58 PF03576.9 CBZ53419.1 - 5.6e-10 38.9 10.8 1.3e-09 37.6 0.8 3.1 3 0 0 3 3 3 2 Peptidase family S58 Chorein_N PF12624.2 CBZ53420.1 - 3.8e-07 29.6 0.0 7.9e-07 28.6 0.0 1.6 1 0 0 1 1 1 1 N-terminal region of Chorein, a TM vesicle-mediated sorter Na_H_antiporter PF03553.9 CBZ53420.1 - 0.54 9.2 0.4 1 8.3 0.2 1.3 1 0 0 1 1 1 0 Na+/H+ antiporter family DUF1162 PF06650.7 CBZ53420.1 - 1.3 8.2 0.0 6.6 5.8 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1162) CCDC144C PF14915.1 CBZ53420.1 - 2.7 6.8 2.2 5.2 5.8 1.5 1.4 1 0 0 1 1 1 0 CCDC144C protein coiled-coil region dTDP_sugar_isom PF00908.12 CBZ53420.1 - 4.4 6.6 0.2 8 5.7 0.1 1.3 1 0 0 1 1 1 0 dTDP-4-dehydrorhamnose 3,5-epimerase Ribosomal_S15 PF00312.17 CBZ53420.1 - 5.2 6.8 0.4 14 5.5 0.3 1.7 1 0 0 1 1 1 0 Ribosomal protein S15 3HCDH_N PF02737.13 CBZ53421.1 - 1.2e-35 122.7 0.4 2.4e-35 121.8 0.2 1.5 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.17 CBZ53421.1 - 1.5e-35 121.5 0.0 2.6e-35 120.6 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain AalphaY_MDB PF04611.7 CBZ53421.1 - 0.04 13.8 0.3 0.082 12.7 0.2 1.5 1 0 0 1 1 1 0 Mating type protein A alpha Y mating type dependent binding region RAP PF08373.5 CBZ53422.1 - 5.5e-09 35.6 0.0 8.9e-08 31.8 0.0 2.5 2 1 0 2 2 2 1 RAP domain DUF559 PF04480.7 CBZ53422.1 - 0.0079 15.8 3.8 0.03 13.9 0.0 3.0 3 0 0 3 3 3 1 Protein of unknown function (DUF559) RAP1 PF07218.6 CBZ53422.1 - 0.058 11.4 5.7 0.12 10.4 3.9 1.4 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DUF221 PF02714.10 CBZ53423.1 - 2.2e-32 112.2 22.0 3e-31 108.4 13.7 2.1 2 0 0 2 2 2 2 Domain of unknown function DUF221 RSN1_TM PF13967.1 CBZ53423.1 - 0.00023 20.7 1.9 0.0011 18.5 0.1 2.6 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport Reg_prop PF07494.6 CBZ53424.1 - 1.1e-05 24.9 4.1 0.34 11.0 0.0 4.3 5 0 0 5 5 5 3 Two component regulator propeller PSII_BNR PF14870.1 CBZ53424.1 - 4.2e-05 22.6 1.2 8.1e-05 21.7 0.4 1.6 1 1 1 2 2 2 1 Photosynthesis system II assembly factor YCF48 zf-RING_2 PF13639.1 CBZ53427.1 - 1.4e-12 47.2 14.3 3.4e-12 46.0 9.9 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 CBZ53427.1 - 3.9e-06 26.4 8.4 9.9e-06 25.1 5.8 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CBZ53427.1 - 9.2e-06 25.5 9.8 2.5e-05 24.2 6.8 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 CBZ53427.1 - 6.4e-05 22.9 11.0 0.0002 21.4 7.6 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 CBZ53427.1 - 8.2e-05 22.2 8.5 0.0002 21.0 5.9 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 CBZ53427.1 - 0.091 12.6 5.1 0.19 11.5 3.5 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger RINGv PF12906.2 CBZ53427.1 - 0.13 12.2 11.0 0.38 10.8 7.6 1.8 1 0 0 1 1 1 0 RING-variant domain FANCL_C PF11793.3 CBZ53427.1 - 0.18 11.7 7.5 0.4 10.6 5.2 1.6 1 0 0 1 1 1 0 FANCL C-terminal domain PIG-S PF10510.4 CBZ53429.1 - 9.8e-30 103.6 6.3 1.2e-13 50.6 0.9 3.9 3 1 0 3 3 3 3 Phosphatidylinositol-glycan biosynthesis class S protein BAR PF03114.13 CBZ53430.1 - 0.00012 21.6 1.7 0.00032 20.2 1.2 1.6 1 0 0 1 1 1 1 BAR domain UBA PF00627.26 CBZ53430.1 - 0.00044 20.0 0.1 0.0015 18.3 0.0 2.0 2 0 0 2 2 2 1 UBA/TS-N domain Sec7 PF01369.15 CBZ53431.1 - 4.1e-62 209.2 0.0 6.7e-62 208.5 0.0 1.3 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.2 CBZ53431.1 - 0.0027 17.1 0.0 0.018 14.5 0.0 2.2 1 1 0 1 1 1 1 Guanine nucleotide exchange factor in Golgi transport N-terminal Pacifastin_I PF05375.8 CBZ53432.1 - 0.089 12.3 2.1 0.22 11.0 1.4 1.7 1 1 0 1 1 1 0 Pacifastin inhibitor (LCMII) TMEM187 PF15100.1 CBZ53432.1 - 0.12 11.6 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 TMEM187 protein family Corona_nucleoca PF00937.13 CBZ53433.1 - 0.049 12.5 0.9 0.083 11.8 0.6 1.3 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein SWIB PF02201.13 CBZ53434.1 - 5.3e-10 38.8 0.0 1e-09 37.9 0.0 1.4 1 0 0 1 1 1 1 SWIB/MDM2 domain SAM_1 PF00536.25 CBZ53434.1 - 0.002 18.2 0.0 0.0032 17.6 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 CBZ53434.1 - 0.0044 16.8 0.0 0.0071 16.1 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Ribosomal_L7Ae PF01248.21 CBZ53435.1 - 6.7e-25 86.4 0.1 7.7e-25 86.2 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Hydrolase_6 PF13344.1 CBZ53435.1 - 0.017 14.9 0.0 0.022 14.6 0.0 1.2 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase APP_Cu_bd PF12924.2 CBZ53435.1 - 0.026 15.0 0.0 0.044 14.2 0.0 1.5 1 0 0 1 1 1 0 Copper-binding of amyloid precursor, CuBD DPBB_1 PF03330.13 CBZ53435.1 - 0.14 12.1 0.0 1.9 8.5 0.0 2.1 2 0 0 2 2 2 0 Rare lipoprotein A (RlpA)-like double-psi beta-barrel zf-SNAP50_C PF12251.3 CBZ53436.1 - 1.3e-29 102.9 0.3 1.5e-23 83.1 0.2 2.2 2 0 0 2 2 2 2 snRNA-activating protein of 50kDa MW C terminal Catalase PF00199.14 CBZ53437.1 - 9.5e-183 607.1 6.6 3.8e-182 605.1 4.6 1.7 1 1 0 1 1 1 1 Catalase Catalase-rel PF06628.7 CBZ53437.1 - 1.1e-21 76.3 0.0 3.1e-21 74.9 0.0 1.7 1 0 0 1 1 1 1 Catalase-related immune-responsive Cadherin_2 PF08266.7 CBZ53437.1 - 0.041 13.4 0.0 0.074 12.6 0.0 1.3 1 0 0 1 1 1 0 Cadherin-like His_Phos_2 PF00328.17 CBZ53439.1 - 0.034 13.4 0.0 4.4 6.5 0.0 2.2 2 0 0 2 2 2 0 Histidine phosphatase superfamily (branch 2) ANAPC15 PF15243.1 CBZ53440.1 - 0.28 11.2 3.9 0.55 10.3 2.7 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 15 Menin PF05053.8 CBZ53440.1 - 1.5 6.9 4.7 4.8 5.2 0.1 2.0 2 0 0 2 2 2 0 Menin Ribosomal_S3_C PF00189.15 CBZ53442.1 - 6.6e-16 58.2 0.3 1.3e-15 57.3 0.2 1.5 1 0 0 1 1 1 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.12 CBZ53442.1 - 8.3e-10 38.0 0.0 1.3e-09 37.4 0.0 1.3 1 0 0 1 1 1 1 KH domain Exo_endo_phos PF03372.18 CBZ53443.1 - 4.8e-08 33.2 0.0 9e-08 32.3 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Polyoma_lg_T_C PF06431.6 CBZ53444.1 - 0.65 8.5 0.2 1.2 7.7 0.2 1.3 1 0 0 1 1 1 0 Polyomavirus large T antigen C-terminus Spore_coat_CotO PF14153.1 CBZ53444.1 - 1.8 7.9 9.9 8.4 5.7 1.8 3.0 3 0 0 3 3 3 0 Spore coat protein CotO PP2C PF00481.16 CBZ53445.1 - 2e-60 204.3 1.2 5.1e-55 186.6 0.1 3.5 2 1 0 2 2 2 2 Protein phosphatase 2C SpoIIE PF07228.7 CBZ53445.1 - 0.014 15.0 0.1 0.098 12.3 0.1 2.1 1 1 0 1 1 1 0 Stage II sporulation protein E (SpoIIE) Hid1 PF12722.2 CBZ53445.1 - 5.6 4.5 7.9 7.7 4.0 5.5 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Ldh_1_N PF00056.18 CBZ53446.1 - 2.3e-36 124.7 0.1 3.6e-36 124.0 0.1 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 CBZ53446.1 - 1.7e-33 115.8 0.0 3.1e-33 114.9 0.0 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Glyco_hydro_4 PF02056.11 CBZ53446.1 - 0.00012 21.5 0.3 0.0073 15.6 0.2 2.4 2 0 0 2 2 2 1 Family 4 glycosyl hydrolase 3Beta_HSD PF01073.14 CBZ53446.1 - 0.0046 15.6 0.2 0.0099 14.6 0.0 1.6 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family UDPG_MGDP_dh_N PF03721.9 CBZ53446.1 - 0.016 14.5 1.2 0.052 12.9 0.8 1.9 1 1 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3HCDH_N PF02737.13 CBZ53446.1 - 0.083 12.5 0.3 0.19 11.3 0.2 1.7 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain RNase_T PF00929.19 CBZ53447.1 - 4.8e-13 49.7 0.0 8.8e-13 48.8 0.0 1.4 1 0 0 1 1 1 1 Exonuclease UCH_1 PF13423.1 CBZ53447.1 - 1.2e-08 34.7 0.0 2.2e-08 33.8 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-CW PF07496.10 CBZ53448.1 - 1.3e-30 104.7 41.7 1.2e-12 47.2 6.0 3.4 3 0 0 3 3 3 3 CW-type Zinc Finger zinc_ribbon_5 PF13719.1 CBZ53448.1 - 0.45 10.1 5.5 19 4.9 0.1 3.5 3 0 0 3 3 3 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 CBZ53448.1 - 1.4 8.6 4.5 53 3.6 0.0 3.4 3 0 0 3 3 3 0 zinc-ribbon domain WD40 PF00400.27 CBZ53449.1 - 7.8e-44 146.0 19.8 4.1e-09 35.9 0.0 11.0 11 0 0 11 11 11 8 WD domain, G-beta repeat Nup160 PF11715.3 CBZ53449.1 - 0.0025 16.0 3.0 0.15 10.2 0.2 3.7 3 1 1 4 4 4 1 Nucleoporin Nup120/160 Utp12 PF04003.7 CBZ53449.1 - 0.0072 16.2 1.0 0.56 10.1 0.1 2.5 2 0 0 2 2 2 1 Dip2/Utp12 Family Nucleoporin_N PF08801.6 CBZ53449.1 - 0.038 12.7 0.3 1.1 7.9 0.0 3.1 5 0 0 5 5 5 0 Nup133 N terminal like RTC PF01137.16 CBZ53450.1 - 1.6e-47 161.2 0.0 1.7e-46 157.8 0.0 1.9 1 1 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.8 CBZ53450.1 - 6e-17 61.5 3.0 1.6e-15 56.9 0.3 2.3 2 0 0 2 2 2 2 RNA 3'-terminal phosphate cyclase (RTC), insert domain PAN_1 PF00024.21 CBZ53451.1 - 5.8e-26 90.0 28.3 1.3e-07 31.2 2.1 4.3 3 1 1 4 4 4 4 PAN domain PAN_4 PF14295.1 CBZ53451.1 - 2e-14 53.0 24.7 3.1e-05 23.6 0.2 4.6 5 0 0 5 5 5 4 PAN domain PAN_2 PF08276.6 CBZ53451.1 - 1.8e-06 27.6 29.0 0.015 15.1 1.0 4.5 4 0 0 4 4 4 4 PAN-like domain PAN_3 PF08277.7 CBZ53451.1 - 5.7e-05 22.6 15.9 0.41 10.2 0.5 4.3 4 0 0 4 4 4 4 PAN-like domain DUF3426 PF11906.3 CBZ53451.1 - 0.093 12.3 0.6 0.17 11.5 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3426) Thioredoxin_8 PF13905.1 CBZ53452.1 - 2.4e-23 82.0 0.0 3.7e-23 81.4 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.16 CBZ53452.1 - 0.00025 20.6 0.0 0.00042 19.9 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_2 PF13098.1 CBZ53452.1 - 0.013 15.7 0.0 0.022 14.9 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin-like domain Redoxin PF08534.5 CBZ53452.1 - 0.021 14.3 0.0 0.031 13.8 0.0 1.2 1 0 0 1 1 1 0 Redoxin SPX PF03105.14 CBZ53456.1 - 2.3e-06 27.6 0.4 2.3e-06 27.6 0.3 3.2 1 1 0 3 3 3 2 SPX domain Baculo_PEP_C PF04513.7 CBZ53456.1 - 5.2 6.8 9.3 9.4 6.0 0.4 3.6 3 1 1 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus CALCOCO1 PF07888.6 CBZ53456.1 - 9.4 4.3 41.6 0.81 7.9 6.2 3.6 3 1 1 4 4 4 0 Calcium binding and coiled-coil domain (CALCOCO1) like NPV_P10 PF05531.7 CBZ53456.1 - 9.8 6.5 11.7 0.56 10.4 1.5 3.7 3 1 2 5 5 5 0 Nucleopolyhedrovirus P10 protein SNF2_N PF00176.18 CBZ53457.1 - 6.5e-63 212.2 0.0 8.5e-63 211.9 0.0 1.1 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 CBZ53457.1 - 4.1e-13 48.9 0.0 7.7e-13 48.1 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 CBZ53457.1 - 9.9e-08 31.6 0.0 2.1e-07 30.5 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 CBZ53457.1 - 1.9e-07 31.0 0.0 5.2e-07 29.6 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.3 CBZ53457.1 - 1.8e-06 27.0 0.0 5.2e-06 25.4 0.0 1.8 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 DUF2075 PF09848.4 CBZ53457.1 - 0.016 14.2 0.0 0.04 12.8 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) CDC37_N PF03234.9 CBZ53459.1 - 4.7 7.4 21.5 14 5.9 8.9 2.8 1 1 1 2 2 2 0 Cdc37 N terminal kinase binding INCENP_ARK-bind PF03941.10 CBZ53460.1 - 0.082 12.7 0.2 0.81 9.5 0.0 2.3 2 0 0 2 2 2 0 Inner centromere protein, ARK binding region Pox_M2 PF04887.7 CBZ53460.1 - 0.15 11.4 0.0 0.25 10.6 0.0 1.2 1 0 0 1 1 1 0 Poxvirus M2 protein zf-RING_2 PF13639.1 CBZ53461.1 - 1.2e-06 28.2 2.6 1.2e-06 28.2 1.8 4.6 4 0 0 4 4 4 1 Ring finger domain zf-rbx1 PF12678.2 CBZ53461.1 - 5.6e-05 23.1 2.5 0.00028 20.9 0.1 3.2 3 0 0 3 3 3 1 RING-H2 zinc finger zf-UBP PF02148.14 CBZ53461.1 - 0.00034 20.6 15.4 0.0019 18.3 0.2 3.9 2 1 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein zf-C3HC4 PF00097.20 CBZ53461.1 - 0.0013 18.3 0.8 0.0013 18.3 0.6 3.5 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CBZ53461.1 - 0.0018 18.2 1.7 0.0018 18.2 1.1 4.5 5 0 0 5 5 5 1 Zinc finger, C3HC4 type (RING finger) BRAP2 PF07576.7 CBZ53461.1 - 0.044 13.3 0.0 0.082 12.4 0.0 1.3 1 0 0 1 1 1 0 BRCA1-associated protein 2 Brix PF04427.13 CBZ53462.1 - 6.4e-28 97.7 0.0 5.6e-27 94.6 0.0 2.2 1 1 0 1 1 1 1 Brix domain UL11 PF11094.3 CBZ53462.1 - 0.069 12.9 0.5 14 5.5 0.1 2.9 2 0 0 2 2 2 0 Membrane-associated tegument protein SUV3_C PF12513.3 CBZ53463.1 - 1.4e-13 50.0 0.0 2.5e-13 49.2 0.0 1.5 1 0 0 1 1 1 1 Mitochondrial degradasome RNA helicase subunit C terminal Helicase_C PF00271.26 CBZ53463.1 - 2.5e-08 33.6 0.0 2.3e-05 24.1 0.0 2.5 2 0 0 2 2 2 2 Helicase conserved C-terminal domain Zot PF05707.7 CBZ53463.1 - 0.15 11.5 0.0 0.28 10.6 0.0 1.4 1 0 0 1 1 1 0 Zonular occludens toxin (Zot) FAD_binding_3 PF01494.14 CBZ53464.1 - 1.2e-43 149.5 0.6 9.1e-17 61.1 0.0 4.3 4 0 0 4 4 4 3 FAD binding domain DAO PF01266.19 CBZ53464.1 - 0.0015 17.5 0.0 0.0029 16.5 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 CBZ53464.1 - 0.017 15.4 0.0 0.042 14.2 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.13 CBZ53464.1 - 0.029 14.3 0.0 0.07 13.1 0.0 1.7 1 0 0 1 1 1 0 TrkA-N domain NAD_binding_8 PF13450.1 CBZ53464.1 - 0.041 13.9 0.0 0.11 12.4 0.0 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain YycC PF14174.1 CBZ53464.1 - 0.05 13.2 0.2 0.16 11.6 0.1 1.8 1 0 0 1 1 1 0 YycC-like protein Latarcin PF10279.4 CBZ53465.1 - 0.043 14.0 0.6 5.3 7.3 0.0 2.3 2 0 0 2 2 2 0 Latarcin precursor DUF4145 PF13643.1 CBZ53465.1 - 0.068 13.0 0.1 0.16 11.8 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4145) AnfO_nitrog PF09582.5 CBZ53465.1 - 0.17 11.0 1.2 2.6 7.1 0.0 2.1 1 1 0 2 2 2 0 Iron only nitrogenase protein AnfO (AnfO_nitrog) DUF883 PF05957.8 CBZ53465.1 - 0.2 12.0 6.3 2.1 8.7 0.8 2.4 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) FA PF08736.6 CBZ53466.1 - 0.041 13.6 0.1 0.21 11.4 0.1 2.3 1 0 0 1 1 1 0 FERM adjacent (FA) AMP-binding PF00501.23 CBZ53467.1 - 4.4e-80 269.1 0.0 6e-80 268.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 CBZ53467.1 - 1e-17 64.8 2.3 2.9e-17 63.3 1.4 2.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain DUF1967 PF09269.6 CBZ53467.1 - 0.042 13.5 0.1 0.5 10.0 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF1967) GCS PF03074.11 CBZ53468.1 - 6.9e-93 311.6 0.0 3.6e-48 164.4 0.0 3.1 2 1 1 3 3 3 3 Glutamate-cysteine ligase Patatin PF01734.17 CBZ53469.1 - 2.2e-11 44.0 0.3 7.7e-10 39.0 0.1 2.4 2 0 0 2 2 2 2 Patatin-like phospholipase NuA4 PF09340.5 CBZ53470.1 - 2.8e-19 68.5 0.0 5.9e-19 67.4 0.0 1.6 1 0 0 1 1 1 1 Histone acetyltransferase subunit NuA4 DSPc PF00782.15 CBZ53471.1 - 0.00031 20.3 0.0 0.00057 19.4 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTEN_C2 PF10409.4 CBZ53471.1 - 0.00038 20.1 0.0 0.17 11.5 0.0 2.4 2 1 0 2 2 2 2 C2 domain of PTEN tumour-suppressor protein Y_phosphatase PF00102.22 CBZ53471.1 - 0.054 12.8 0.0 0.087 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase PTS_2-RNA PF01885.11 CBZ53473.1 - 5.5e-52 175.7 0.0 8e-52 175.2 0.0 1.2 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family PHD PF00628.24 CBZ53474.1 - 8.5e-05 22.1 7.9 0.00023 20.7 5.4 1.7 1 0 0 1 1 1 1 PHD-finger zf-RING_2 PF13639.1 CBZ53474.1 - 0.14 12.0 9.3 0.41 10.5 6.4 1.9 1 0 0 1 1 1 0 Ring finger domain zf-RanBP PF00641.13 CBZ53474.1 - 0.18 10.9 4.6 0.28 10.3 0.2 3.1 3 0 0 3 3 3 0 Zn-finger in Ran binding protein and others TPR_11 PF13414.1 CBZ53475.1 - 9.6e-20 70.0 3.7 3e-10 39.5 0.6 2.7 2 1 1 3 3 3 2 TPR repeat TPR_1 PF00515.23 CBZ53475.1 - 2.5e-07 30.0 3.4 3.1e-05 23.3 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 CBZ53475.1 - 2.1e-05 25.0 3.3 0.00049 20.6 0.1 3.0 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.1 CBZ53475.1 - 0.00033 20.6 0.1 0.011 15.8 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 CBZ53475.1 - 0.0013 18.5 0.0 0.0013 18.5 0.0 3.9 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_9 PF13371.1 CBZ53475.1 - 0.01 15.6 0.1 0.043 13.6 0.1 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat Sporozoite_P67 PF05642.6 CBZ53475.1 - 0.032 12.1 0.1 0.036 11.9 0.1 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen TPR_14 PF13428.1 CBZ53475.1 - 0.045 14.3 0.0 0.045 14.3 0.0 2.8 2 1 1 3 3 3 0 Tetratricopeptide repeat R_equi_Vir PF05526.6 CBZ53475.1 - 0.15 11.6 0.3 1.8 8.1 0.0 2.3 2 0 0 2 2 2 0 Rhodococcus equi virulence-associated protein HxlR PF01638.12 CBZ53477.1 - 1 9.0 3.7 1.2 8.8 0.3 2.3 2 0 0 2 2 2 0 HxlR-like helix-turn-helix TPT PF03151.11 CBZ53478.1 - 2e-19 69.7 13.6 2e-19 69.7 9.4 2.0 2 1 1 3 3 3 1 Triose-phosphate Transporter family CbtB PF09489.5 CBZ53478.1 - 0.34 10.8 6.4 0.61 10.0 0.6 2.8 2 0 0 2 2 2 0 Probable cobalt transporter subunit (CbtB) UAA PF08449.6 CBZ53478.1 - 0.38 9.6 12.4 0.83 8.5 8.6 1.6 1 1 0 1 1 1 0 UAA transporter family EamA PF00892.15 CBZ53478.1 - 8.4 6.4 30.0 0.93 9.5 12.0 3.2 2 1 1 3 3 3 0 EamA-like transporter family Ribosomal_S3Ae PF01015.13 CBZ53479.1 - 9.5e-82 273.0 0.3 1.2e-81 272.7 0.2 1.1 1 0 0 1 1 1 1 Ribosomal S3Ae family Bul1_C PF04426.7 CBZ53479.1 - 0.081 12.1 0.2 0.11 11.7 0.1 1.2 1 0 0 1 1 1 0 Bul1 C terminus AD PF09793.4 CBZ53480.1 - 2.3e-20 72.2 0.0 3.6e-20 71.6 0.0 1.2 1 0 0 1 1 1 1 Anticodon-binding domain MBOAT PF03062.14 CBZ53481.1 - 1.5e-17 63.7 17.9 1.5e-17 63.7 12.4 1.5 2 0 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.1 CBZ53481.1 - 1.5e-06 28.1 4.0 5.5e-06 26.3 2.8 2.0 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family Methyltransf_10 PF05971.7 CBZ53483.1 - 3.3e-67 226.7 2.2 1.7e-42 145.6 0.1 4.0 3 1 0 3 3 3 3 Protein of unknown function (DUF890) MTS PF05175.9 CBZ53483.1 - 2.2e-06 27.1 0.0 4e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 CBZ53483.1 - 3.3e-05 23.8 0.0 0.0001 22.2 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CBZ53483.1 - 0.00029 21.3 0.0 0.00073 20.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CBZ53483.1 - 0.01 16.2 0.0 0.054 13.8 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_11 PF08241.7 CBZ53483.1 - 0.022 15.2 0.0 0.065 13.7 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.1 CBZ53483.1 - 0.024 14.2 0.0 0.049 13.2 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain UPF0020 PF01170.13 CBZ53483.1 - 0.027 14.0 0.0 0.063 12.8 0.0 1.5 1 1 0 1 1 1 0 Putative RNA methylase family UPF0020 Methyltransf_12 PF08242.7 CBZ53483.1 - 0.11 12.9 0.0 1.8 9.1 0.0 2.7 2 1 1 3 3 3 0 Methyltransferase domain IPP-2 PF04979.9 CBZ53484.1 - 2.8e-17 63.1 6.6 3.7e-17 62.8 4.6 1.2 1 0 0 1 1 1 1 Protein phosphatase inhibitor 2 (IPP-2) COPR5 PF15340.1 CBZ53484.1 - 0.47 10.8 3.7 0.31 11.3 1.2 1.7 1 1 1 2 2 2 0 Cooperator of PRMT5 family Evr1_Alr PF04777.8 CBZ53488.1 - 4.4e-10 39.3 0.2 6.4e-10 38.8 0.1 1.2 1 0 0 1 1 1 1 Erv1 / Alr family zf-Tim10_DDP PF02953.10 CBZ53489.1 - 6.6e-18 63.7 2.4 8.1e-18 63.4 1.7 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger GlutR_dimer PF00745.15 CBZ53489.1 - 0.095 12.6 0.0 0.12 12.2 0.0 1.1 1 0 0 1 1 1 0 Glutamyl-tRNAGlu reductase, dimerisation domain V_ATPase_I PF01496.14 CBZ53490.1 - 4.8e-176 586.8 0.0 5.6e-176 586.6 0.0 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family HSBP1 PF06825.7 CBZ53490.1 - 0.1 12.1 0.1 0.3 10.6 0.1 1.8 1 0 0 1 1 1 0 Heat shock factor binding protein 1 HSP20 PF00011.16 CBZ53491.1 - 3.4e-15 55.7 0.0 5.8e-15 55.0 0.0 1.3 1 0 0 1 1 1 1 Hsp20/alpha crystallin family 2OG-FeII_Oxy_3 PF13640.1 CBZ53493.1 - 5.5e-14 52.4 0.0 8.8e-14 51.8 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 CBZ53493.1 - 1.1e-06 28.1 0.0 2.1e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 CBZ53493.1 - 0.0086 16.3 0.0 0.014 15.7 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily ORC5_C PF14630.1 CBZ53494.1 - 1.8e-14 53.8 0.1 1.3e-13 51.0 0.1 2.2 2 1 0 2 2 2 1 Origin recognition complex (ORC) subunit 5 C-terminus AAA_22 PF13401.1 CBZ53494.1 - 0.1 12.7 0.1 26 4.9 0.0 2.9 3 0 0 3 3 3 0 AAA domain Spt5-NGN PF03439.8 CBZ53496.1 - 1.1e-20 73.0 0.1 2.1e-20 72.2 0.1 1.5 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section Spt5_N PF11942.3 CBZ53496.1 - 1.5e-08 35.1 13.9 1.5e-08 35.1 9.6 3.3 3 0 0 3 3 3 1 Spt5 transcription elongation factor, acidic N-terminal KOW PF00467.24 CBZ53496.1 - 1.2e-07 31.1 7.3 0.6 9.9 0.0 5.8 5 0 0 5 5 5 4 KOW motif Pkinase PF00069.20 CBZ53497.1 - 1.5e-71 240.5 0.0 2.4e-71 239.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ53497.1 - 2.9e-33 115.0 0.0 5e-33 114.2 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBZ53497.1 - 2e-07 30.2 0.0 1.8e-06 27.1 0.0 2.2 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.9 CBZ53497.1 - 0.012 14.7 0.2 0.022 13.8 0.1 1.5 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PDEase_I PF00233.14 CBZ53499.1 - 1.3e-35 123.2 0.9 2.5e-35 122.3 0.6 1.4 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase HD PF01966.17 CBZ53499.1 - 0.0024 17.8 0.4 0.0083 16.1 0.1 2.1 2 0 0 2 2 2 1 HD domain PDEase_I PF00233.14 CBZ53500.1 - 1.7e-52 178.5 0.4 8.6e-52 176.2 0.0 2.1 2 0 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase HATPase_c PF02518.21 CBZ53500.1 - 6.7e-07 29.0 0.0 1.4e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Herpes_UL32 PF06070.6 CBZ53500.1 - 0.11 10.9 0.1 0.16 10.4 0.1 1.1 1 0 0 1 1 1 0 Herpesvirus large structural phosphoprotein UL32 GCFC PF07842.7 CBZ53501.1 - 5e-41 140.8 16.1 4.4e-37 127.9 7.3 3.0 3 0 0 3 3 3 2 GC-rich sequence DNA-binding factor-like protein G-patch PF01585.18 CBZ53501.1 - 1.8e-10 40.4 1.4 1.8e-10 40.4 0.9 2.3 2 0 0 2 2 2 1 G-patch domain XPG_N PF00752.12 CBZ53502.1 - 3.1e-21 75.5 0.0 6.2e-21 74.5 0.0 1.5 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.13 CBZ53502.1 - 1.5e-07 31.3 0.1 4e-07 30.0 0.0 1.7 1 0 0 1 1 1 1 XPG I-region Band_7 PF01145.20 CBZ53503.1 - 5.1e-23 81.8 0.1 8.4e-23 81.1 0.1 1.3 1 0 0 1 1 1 1 SPFH domain / Band 7 family FUSC PF04632.7 CBZ53503.1 - 2.6 6.3 5.3 3.4 5.9 3.7 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family IMPDH PF00478.20 CBZ53504.1 - 5.8e-94 314.8 16.8 2.1e-44 151.8 0.0 4.0 3 1 1 4 4 4 4 IMP dehydrogenase / GMP reductase domain CBS PF00571.23 CBZ53504.1 - 2.6e-15 55.9 0.1 1.1e-07 31.4 0.0 2.5 2 0 0 2 2 2 2 CBS domain NMO PF03060.10 CBZ53504.1 - 8.9e-07 28.3 0.3 0.015 14.5 0.0 2.9 3 0 0 3 3 3 2 Nitronate monooxygenase DUF4107 PF13389.1 CBZ53504.1 - 0.12 12.1 0.1 0.28 10.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4107) AP2 PF00847.15 CBZ53505.1 - 6.3e-27 93.4 39.9 1.2e-06 28.6 2.0 7.2 7 0 0 7 7 7 5 AP2 domain AF-4 PF05110.8 CBZ53505.1 - 0.02 12.7 13.5 0.034 12.0 7.0 2.4 2 0 0 2 2 2 0 AF-4 proto-oncoprotein CDC45 PF02724.9 CBZ53505.1 - 6.9 4.5 4.0 11 3.9 2.8 1.1 1 0 0 1 1 1 0 CDC45-like protein Nucleoside_tran PF01733.13 CBZ53506.1 - 8.1e-24 84.3 3.2 7.5e-22 77.8 2.2 2.2 1 1 0 1 1 1 1 Nucleoside transporter Shisa PF13908.1 CBZ53506.1 - 0.12 12.4 0.0 0.28 11.3 0.0 1.5 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator dUTPase PF00692.14 CBZ53507.1 - 2.9e-16 59.0 0.0 1e-15 57.3 0.0 1.7 1 1 0 1 1 1 1 dUTPase HTH_23 PF13384.1 CBZ53509.1 - 5.2e-06 25.9 0.1 1.8e-05 24.2 0.1 1.9 1 0 0 1 1 1 1 Homeodomain-like domain HTH_Tnp_4 PF13613.1 CBZ53509.1 - 0.011 15.2 0.2 0.02 14.3 0.1 1.4 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease HTH_3 PF01381.17 CBZ53509.1 - 0.16 11.8 0.0 0.16 11.8 0.0 2.4 2 0 0 2 2 2 0 Helix-turn-helix DUF2003 PF09404.5 CBZ53509.1 - 0.19 10.0 0.0 0.3 9.4 0.0 1.2 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF2003) DUF3633 PF12315.3 CBZ53511.1 - 3.1e-10 39.7 0.0 7.5e-10 38.4 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF3633) Peptidase_MA_2 PF13485.1 CBZ53511.1 - 0.013 15.5 0.0 0.026 14.5 0.0 1.5 1 0 0 1 1 1 0 Peptidase MA superfamily DUF4211 PF13926.1 CBZ53511.1 - 0.026 13.9 0.1 0.093 12.1 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4211) GAD PF02938.9 CBZ53511.1 - 0.15 12.2 0.0 0.36 11.0 0.0 1.6 1 0 0 1 1 1 0 GAD domain SKIP_SNW PF02731.10 CBZ53512.1 - 1.2e-63 213.2 5.1 1.2e-63 213.2 3.5 2.5 3 0 0 3 3 3 1 SKIP/SNW domain DUF2756 PF10956.3 CBZ53512.1 - 1.9 8.8 0.0 1.9 8.8 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2756) Urm1 PF09138.6 CBZ53513.1 - 1.4e-17 63.5 0.0 4.6e-14 52.3 0.0 2.2 2 0 0 2 2 2 2 Urm1 (Ubiquitin related modifier) CENP-B_dimeris PF09026.5 CBZ53515.1 - 0.046 13.9 0.2 0.13 12.4 0.1 1.8 1 0 0 1 1 1 0 Centromere protein B dimerisation domain RRM_1 PF00076.17 CBZ53516.1 - 1.2e-18 66.5 0.2 1.8e-18 65.9 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBZ53516.1 - 7.2e-13 48.3 0.0 1.1e-12 47.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBZ53516.1 - 1.8e-10 40.4 0.0 2.8e-10 39.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 CBZ53516.1 - 0.017 14.8 0.0 0.039 13.6 0.0 1.7 1 1 1 2 2 2 0 Limkain b1 MMR_HSR1 PF01926.18 CBZ53518.1 - 2.8e-16 59.5 0.0 5.7e-16 58.5 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase TGS PF02824.16 CBZ53518.1 - 5.5e-15 54.9 0.0 9.4e-15 54.2 0.0 1.4 1 0 0 1 1 1 1 TGS domain FeoB_N PF02421.13 CBZ53518.1 - 3.2e-08 32.9 0.0 0.0022 17.2 0.0 2.3 2 0 0 2 2 2 2 Ferrous iron transport protein B Dynamin_N PF00350.18 CBZ53518.1 - 1.8e-06 27.9 0.2 0.0049 16.7 0.0 2.3 2 0 0 2 2 2 2 Dynamin family GTP_EFTU PF00009.22 CBZ53518.1 - 9.9e-05 21.8 0.0 0.0073 15.7 0.0 2.5 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain MCM PF00493.18 CBZ53518.1 - 0.0089 14.8 0.0 0.019 13.7 0.0 1.5 1 0 0 1 1 1 1 MCM2/3/5 family FliD_N PF02465.13 CBZ53518.1 - 0.035 14.4 1.5 0.16 12.3 1.0 2.0 1 1 0 1 1 1 0 Flagellar hook-associated protein 2 N-terminus AAA_28 PF13521.1 CBZ53518.1 - 0.044 13.7 0.0 0.093 12.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain Miro PF08477.8 CBZ53518.1 - 0.05 14.0 0.0 0.22 12.0 0.0 2.1 1 1 0 1 1 1 0 Miro-like protein ArgK PF03308.11 CBZ53518.1 - 0.058 12.1 0.3 0.4 9.4 0.0 2.2 2 0 0 2 2 2 0 ArgK protein DUF258 PF03193.11 CBZ53518.1 - 0.076 12.2 0.0 0.13 11.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_33 PF13671.1 CBZ53518.1 - 0.085 12.7 1.6 2.3 8.0 0.0 2.9 2 1 1 3 3 3 0 AAA domain MORN PF02493.15 CBZ53519.1 - 8.7e-07 28.3 27.9 0.0028 17.2 1.9 6.5 6 0 0 6 6 6 4 MORN repeat PD40 PF07676.7 CBZ53520.1 - 0.16 11.6 0.8 22 4.8 0.0 3.1 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat CRAL_TRIO_2 PF13716.1 CBZ53521.1 - 2.6e-26 92.3 0.4 4.1e-26 91.6 0.3 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain RhoGAP PF00620.22 CBZ53521.1 - 5.3e-12 45.6 0.0 1.8e-11 43.8 0.0 1.9 2 0 0 2 2 2 1 RhoGAP domain SR-25 PF10500.4 CBZ53521.1 - 0.0033 16.9 23.4 0.005 16.3 7.2 2.2 2 0 0 2 2 2 2 Nuclear RNA-splicing-associated protein DUF755 PF05501.6 CBZ53521.1 - 0.46 10.5 25.9 0.33 11.0 7.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF755) Peptidase_M24 PF00557.19 CBZ53522.1 - 4e-52 176.8 0.6 8.2e-52 175.7 0.0 1.7 2 0 0 2 2 2 1 Metallopeptidase family M24 AMP_N PF05195.11 CBZ53522.1 - 2.2e-15 56.2 0.1 3.9e-15 55.4 0.1 1.4 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain Inositol_P PF00459.20 CBZ53523.1 - 1.7e-06 27.5 0.0 4.5e-06 26.1 0.0 1.6 2 0 0 2 2 2 1 Inositol monophosphatase family EF-hand_8 PF13833.1 CBZ53523.1 - 0.028 14.0 0.1 0.15 11.6 0.0 2.2 2 0 0 2 2 2 0 EF-hand domain pair EF-hand_1 PF00036.27 CBZ53523.1 - 0.057 12.7 0.1 0.17 11.2 0.1 1.8 1 0 0 1 1 1 0 EF hand UL11 PF11094.3 CBZ53523.1 - 0.076 12.8 0.1 11 5.9 0.0 2.6 2 0 0 2 2 2 0 Membrane-associated tegument protein EF-hand_7 PF13499.1 CBZ53523.1 - 0.17 12.0 0.0 1 9.5 0.0 2.3 3 0 0 3 3 3 0 EF-hand domain pair Radial_spoke PF04712.7 CBZ53524.1 - 1.5e-97 327.4 0.0 2.1e-97 326.9 0.0 1.1 1 0 0 1 1 1 1 Radial spokehead-like protein MCM_bind PF09739.4 CBZ53525.1 - 1.4e-12 47.2 0.0 1.4e-06 27.8 0.0 2.6 2 0 0 2 2 2 2 Mini-chromosome maintenance replisome factor NADH_Oxid_Nqo15 PF11497.3 CBZ53525.1 - 0.017 14.8 0.0 0.034 13.8 0.0 1.4 1 0 0 1 1 1 0 NADH-quinone oxidoreductase chain 15 DUF4407 PF14362.1 CBZ53525.1 - 0.12 11.2 1.1 0.2 10.5 0.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) NTF2 PF02136.15 CBZ53526.1 - 2e-30 105.6 0.0 2.2e-30 105.4 0.0 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain NAGLU PF05089.7 CBZ53526.1 - 0.091 11.5 0.1 0.1 11.3 0.1 1.1 1 0 0 1 1 1 0 Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain Mtr2 PF10429.4 CBZ53526.1 - 0.095 12.4 0.0 0.11 12.2 0.0 1.1 1 0 0 1 1 1 0 Nuclear pore RNA shuttling protein Mtr2 DDE_Tnp_IS66_C PF13817.1 CBZ53527.1 - 0.0023 17.8 0.0 2.8 8.0 0.0 2.3 2 0 0 2 2 2 2 IS66 C-terminal element VP4_haemagglut PF00426.13 CBZ53529.1 - 0.16 9.9 0.0 0.22 9.4 0.0 1.1 1 0 0 1 1 1 0 Outer Capsid protein VP4 (Hemagglutinin) AAA_18 PF13238.1 CBZ53531.1 - 1.2e-27 96.7 0.1 1.7e-27 96.2 0.1 1.2 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 CBZ53531.1 - 2e-17 64.0 0.1 3.3e-17 63.4 0.1 1.3 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 CBZ53531.1 - 3e-08 33.6 0.0 7e-06 25.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 CBZ53531.1 - 8.6e-06 25.9 0.0 1.8e-05 24.9 0.0 1.6 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) ADK PF00406.17 CBZ53531.1 - 2.2e-05 24.3 0.0 0.00026 20.8 0.0 2.0 2 0 0 2 2 2 1 Adenylate kinase AAA_28 PF13521.1 CBZ53531.1 - 6.4e-05 22.9 0.0 0.00013 22.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 CBZ53531.1 - 8.2e-05 22.7 0.1 0.00014 22.0 0.1 1.7 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 CBZ53531.1 - 9.3e-05 22.3 0.1 0.00028 20.8 0.0 1.9 1 1 1 2 2 2 1 AAA domain NTPase_1 PF03266.10 CBZ53531.1 - 0.00015 21.5 0.3 0.00027 20.6 0.1 1.6 2 0 0 2 2 1 1 NTPase SKI PF01202.17 CBZ53531.1 - 0.00023 21.0 0.1 0.0056 16.5 0.1 2.3 1 1 0 1 1 1 1 Shikimate kinase KTI12 PF08433.5 CBZ53531.1 - 0.00045 19.5 0.0 0.0009 18.5 0.0 1.5 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_16 PF13191.1 CBZ53531.1 - 0.0013 18.7 0.0 0.0032 17.4 0.0 1.7 2 0 0 2 2 2 1 AAA ATPase domain Miro PF08477.8 CBZ53531.1 - 0.0014 19.1 0.1 0.003 18.0 0.0 1.7 2 1 0 2 2 1 1 Miro-like protein FtsK_SpoIIIE PF01580.13 CBZ53531.1 - 0.0014 18.1 0.0 0.0027 17.2 0.0 1.5 1 0 0 1 1 1 1 FtsK/SpoIIIE family RNA_helicase PF00910.17 CBZ53531.1 - 0.0014 18.7 0.0 0.003 17.7 0.0 1.6 1 0 0 1 1 1 1 RNA helicase AAA_10 PF12846.2 CBZ53531.1 - 0.0015 18.0 0.3 0.015 14.7 0.2 2.1 1 1 0 1 1 1 1 AAA-like domain MobB PF03205.9 CBZ53531.1 - 0.0026 17.4 0.0 0.0049 16.5 0.0 1.5 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B NACHT PF05729.7 CBZ53531.1 - 0.003 17.2 0.1 0.01 15.5 0.0 1.8 2 0 0 2 2 2 1 NACHT domain Viral_helicase1 PF01443.13 CBZ53531.1 - 0.0039 16.7 0.0 0.0072 15.8 0.0 1.5 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase IstB_IS21 PF01695.12 CBZ53531.1 - 0.004 16.5 0.0 0.0088 15.4 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein ATP_bind_1 PF03029.12 CBZ53531.1 - 0.0049 16.4 0.2 0.0092 15.5 0.1 1.4 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein KaiC PF06745.8 CBZ53531.1 - 0.0069 15.5 0.0 0.012 14.7 0.0 1.4 1 0 0 1 1 1 1 KaiC AAA_24 PF13479.1 CBZ53531.1 - 0.0073 15.9 0.0 0.014 14.9 0.0 1.5 2 0 0 2 2 1 1 AAA domain RuvB_N PF05496.7 CBZ53531.1 - 0.015 14.3 0.0 0.023 13.7 0.0 1.2 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus UPF0079 PF02367.12 CBZ53531.1 - 0.016 14.8 0.2 0.056 13.0 0.0 1.9 1 1 1 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_5 PF07728.9 CBZ53531.1 - 0.017 14.8 0.0 0.032 13.9 0.0 1.5 2 0 0 2 2 1 0 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 CBZ53531.1 - 0.017 14.7 0.0 0.034 13.7 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) MOSC PF03473.12 CBZ53531.1 - 0.023 14.1 0.1 0.45 9.9 0.0 2.2 2 0 0 2 2 2 0 MOSC domain T2SE PF00437.15 CBZ53531.1 - 0.023 13.6 0.0 0.034 13.0 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein Arch_ATPase PF01637.13 CBZ53531.1 - 0.03 14.0 0.1 1.2 8.8 0.0 2.0 2 0 0 2 2 2 0 Archaeal ATPase SRP54 PF00448.17 CBZ53531.1 - 0.03 13.7 0.0 0.053 12.9 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Zeta_toxin PF06414.7 CBZ53531.1 - 0.036 13.1 0.0 0.082 11.9 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_19 PF13245.1 CBZ53531.1 - 0.045 13.5 0.0 0.074 12.8 0.0 1.4 1 0 0 1 1 1 0 Part of AAA domain AAA_25 PF13481.1 CBZ53531.1 - 0.046 13.1 0.0 0.066 12.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain ArgK PF03308.11 CBZ53531.1 - 0.048 12.4 0.0 0.074 11.8 0.0 1.2 1 0 0 1 1 1 0 ArgK protein PRK PF00485.13 CBZ53531.1 - 0.088 12.3 0.0 0.17 11.4 0.0 1.5 1 1 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family MMR_HSR1 PF01926.18 CBZ53531.1 - 0.088 12.7 0.0 0.11 12.4 0.0 1.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase Sigma54_activat PF00158.21 CBZ53531.1 - 0.11 11.9 0.0 0.48 9.8 0.0 1.9 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_2 PF07724.9 CBZ53531.1 - 0.11 12.3 0.0 0.26 11.1 0.0 1.7 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) Sof1 PF04158.9 CBZ53532.1 - 3.9e-30 103.7 12.8 6.5e-30 102.9 8.9 1.4 1 0 0 1 1 1 1 Sof1-like domain WD40 PF00400.27 CBZ53532.1 - 3.8e-27 93.1 13.8 1.7e-09 37.1 0.0 6.6 7 0 0 7 7 7 4 WD domain, G-beta repeat eIF2A PF08662.6 CBZ53532.1 - 0.0018 18.0 0.0 0.87 9.2 0.0 2.4 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A YbjQ_1 PF01906.12 CBZ53534.1 - 0.0062 16.9 0.0 0.18 12.2 0.0 2.9 3 0 0 3 3 3 1 Putative heavy-metal-binding SAG PF04092.8 CBZ53535.1 - 1.6e-48 164.1 10.4 4.5e-25 88.4 1.9 2.1 2 0 0 2 2 2 2 SRS domain VitD-bind_III PF09164.5 CBZ53535.1 - 0.051 13.1 0.6 0.2 11.2 0.0 2.2 2 0 0 2 2 2 0 Vitamin D binding protein, domain III SAG PF04092.8 CBZ53537.1 - 1.3e-45 154.7 0.3 1.8e-26 92.9 0.0 2.3 2 0 0 2 2 2 2 SRS domain TIM PF00121.13 CBZ53539.1 - 3.3e-82 275.2 0.0 3.9e-82 274.9 0.0 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase OB_NTP_bind PF07717.11 CBZ53540.1 - 3.5e-28 97.7 0.2 6.6e-28 96.8 0.1 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 CBZ53540.1 - 1.6e-25 89.0 0.2 1.6e-25 89.0 0.1 1.8 2 0 0 2 2 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 CBZ53540.1 - 2.6e-11 43.2 0.0 5.4e-11 42.2 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 CBZ53540.1 - 1e-09 38.0 0.3 3.5e-09 36.3 0.2 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.1 CBZ53540.1 - 1.6e-05 25.0 0.0 6.8e-05 23.0 0.0 2.0 2 0 0 2 2 1 1 AAA domain ResIII PF04851.10 CBZ53540.1 - 0.00021 21.2 0.5 0.11 12.3 0.1 2.7 3 0 0 3 3 2 1 Type III restriction enzyme, res subunit Flavi_DEAD PF07652.9 CBZ53540.1 - 0.001 18.8 0.3 0.0031 17.2 0.2 1.8 2 0 0 2 2 2 1 Flavivirus DEAD domain AAA_30 PF13604.1 CBZ53540.1 - 0.0015 18.1 0.7 0.0022 17.5 0.0 1.6 2 0 0 2 2 1 1 AAA domain ABC_tran PF00005.22 CBZ53540.1 - 0.0048 17.2 0.5 0.15 12.3 0.3 2.5 1 1 0 1 1 1 1 ABC transporter T2SE PF00437.15 CBZ53540.1 - 0.0051 15.7 0.0 0.011 14.6 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein KaiC PF06745.8 CBZ53540.1 - 0.0073 15.4 0.0 0.014 14.4 0.0 1.4 1 0 0 1 1 1 1 KaiC AAA_10 PF12846.2 CBZ53540.1 - 0.017 14.5 0.1 0.58 9.5 0.0 2.6 2 1 0 3 3 3 0 AAA-like domain AAA_25 PF13481.1 CBZ53540.1 - 0.019 14.3 0.0 0.29 10.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain SRP54 PF00448.17 CBZ53540.1 - 0.024 14.1 0.4 0.066 12.6 0.2 1.8 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain Zeta_toxin PF06414.7 CBZ53540.1 - 0.024 13.7 0.0 0.051 12.6 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin NACHT PF05729.7 CBZ53540.1 - 0.031 13.9 0.5 0.085 12.5 0.3 1.9 1 1 0 1 1 1 0 NACHT domain AAA_16 PF13191.1 CBZ53540.1 - 0.04 13.9 0.1 0.14 12.1 0.0 2.0 1 1 0 1 1 1 0 AAA ATPase domain AAA_19 PF13245.1 CBZ53540.1 - 0.046 13.4 0.0 0.13 12.0 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain Zot PF05707.7 CBZ53540.1 - 0.069 12.6 0.0 0.14 11.5 0.0 1.5 1 0 0 1 1 1 0 Zonular occludens toxin (Zot) AAA_29 PF13555.1 CBZ53540.1 - 0.075 12.5 0.0 0.19 11.3 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain NB-ARC PF00931.17 CBZ53540.1 - 0.088 11.6 0.0 0.33 9.7 0.0 1.9 2 0 0 2 2 2 0 NB-ARC domain DUF2075 PF09848.4 CBZ53540.1 - 0.1 11.5 0.0 0.16 10.9 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) SRPRB PF09439.5 CBZ53540.1 - 0.15 11.2 0.0 0.93 8.6 0.0 2.1 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit IstB_IS21 PF01695.12 CBZ53540.1 - 0.16 11.3 0.1 1.9 7.9 0.0 2.3 2 0 0 2 2 2 0 IstB-like ATP binding protein MFS_1 PF07690.11 CBZ53542.1 - 1e-12 47.5 39.7 6.2e-07 28.4 9.9 2.8 2 2 0 2 2 2 2 Major Facilitator Superfamily Polyketide_cyc PF03364.15 CBZ53543.1 - 2.9e-08 33.7 0.1 9.6e-08 32.0 0.0 1.9 2 0 0 2 2 2 1 Polyketide cyclase / dehydrase and lipid transport CS PF04969.11 CBZ53545.1 - 8.5e-18 64.6 0.0 1.5e-17 63.9 0.0 1.4 1 0 0 1 1 1 1 CS domain Nudc_N PF14050.1 CBZ53545.1 - 3.6e-15 55.6 0.2 7.7e-15 54.5 0.1 1.6 1 0 0 1 1 1 1 N-terminal conserved domain of Nudc. G0-G1_switch_2 PF15103.1 CBZ53545.1 - 0.18 12.0 2.8 0.26 11.5 0.2 2.1 2 0 0 2 2 2 0 G0/G1 switch protein 2 DUF4404 PF14357.1 CBZ53545.1 - 3.8 7.9 6.6 0.68 10.3 0.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) Atrophin-1 PF03154.10 CBZ53545.1 - 4.8 5.1 12.4 6.7 4.7 8.6 1.2 1 0 0 1 1 1 0 Atrophin-1 family MRAP PF15183.1 CBZ53546.1 - 0.018 14.6 0.0 0.028 14.0 0.0 1.3 1 0 0 1 1 1 0 Melanocortin-2 receptor accessory protein family PsbJ PF01788.12 CBZ53546.1 - 0.038 13.5 0.3 0.067 12.7 0.2 1.4 1 0 0 1 1 1 0 PsbJ Sulfate_transp PF00916.15 CBZ53547.1 - 3.2e-28 98.5 18.1 3.8e-18 65.4 1.2 2.9 2 1 1 3 3 3 2 Sulfate transporter family Sulfate_tra_GLY PF13792.1 CBZ53547.1 - 1.6e-12 46.9 1.7 1.6e-12 46.9 1.2 2.4 3 0 0 3 3 3 1 Sulfate transporter N-terminal domain with GLY motif Peptidase_M50 PF02163.17 CBZ53547.1 - 0.036 13.0 0.0 0.059 12.3 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M50 DUF1673 PF07895.6 CBZ53547.1 - 1.2 8.6 0.8 2.9 7.3 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1673) RNA_pol_Rpb8 PF03870.10 CBZ53548.1 - 1.3e-34 119.3 0.1 1.5e-34 119.1 0.1 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb8 GpcrRhopsn4 PF10192.4 CBZ53550.1 - 3.8e-17 62.3 1.4 4.9e-17 61.9 1.0 1.1 1 0 0 1 1 1 1 Rhodopsin-like GPCR transmembrane domain E1-E2_ATPase PF00122.15 CBZ53551.1 - 3.5e-54 183.2 0.1 4e-53 179.7 0.0 2.4 1 1 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 CBZ53551.1 - 1.9e-34 118.7 11.8 2.2e-17 63.1 3.3 3.3 3 0 0 3 3 3 2 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 CBZ53551.1 - 4e-21 76.4 0.3 1.3e-16 61.7 0.2 2.7 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 CBZ53551.1 - 3.3e-15 55.7 0.0 7.6e-15 54.6 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 CBZ53551.1 - 4.5e-10 40.0 0.6 2.6e-09 37.5 0.4 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 CBZ53551.1 - 7.2e-06 25.3 0.0 3.2e-05 23.2 0.0 2.1 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 CBZ53551.1 - 1.1e-05 25.1 0.5 0.00011 21.8 0.3 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase RAP1 PF07218.6 CBZ53551.1 - 5.2 5.0 2.0 8.2 4.3 1.4 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Milton PF12448.3 CBZ53552.1 - 0.12 12.5 0.4 0.13 12.4 0.3 1.1 1 0 0 1 1 1 0 Kinesin associated protein Pkinase PF00069.20 CBZ53553.1 - 5.1e-58 196.2 0.0 5.7e-58 196.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ53553.1 - 4.9e-27 94.6 0.0 6e-27 94.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 CBZ53553.1 - 0.0047 16.0 0.0 0.0071 15.4 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CBZ53553.1 - 0.08 12.6 0.6 0.34 10.6 0.4 2.0 1 1 0 1 1 1 0 Phosphotransferase enzyme family Sel1 PF08238.7 CBZ53554.1 - 2.7e-06 27.8 20.7 0.15 12.7 1.1 7.0 7 0 0 7 7 7 3 Sel1 repeat DUF3328 PF11807.3 CBZ53554.1 - 0.25 10.9 0.2 22 4.6 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3328) DNA_pol_E_B PF04042.11 CBZ53555.1 - 2.5e-25 88.9 0.0 5.1e-25 87.9 0.0 1.5 1 1 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B GatB_N PF02934.10 CBZ53557.1 - 1.5e-73 247.1 0.0 5.1e-39 133.8 0.0 2.1 2 0 0 2 2 2 2 GatB/GatE catalytic domain GatB_Yqey PF02637.13 CBZ53557.1 - 6.7e-12 45.3 0.0 0.0002 21.1 0.0 3.3 3 0 0 3 3 3 3 GatB domain DUF2666 PF10869.3 CBZ53558.1 - 0.25 11.3 5.3 0.21 11.6 0.1 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2666) tRNA-synt_1d PF00750.14 CBZ53559.1 - 9.9e-44 149.5 0.0 7.1e-23 80.9 0.0 4.1 4 0 0 4 4 4 4 tRNA synthetases class I (R) DALR_1 PF05746.10 CBZ53559.1 - 3e-21 75.5 0.1 6.3e-21 74.5 0.0 1.6 1 0 0 1 1 1 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.11 CBZ53559.1 - 9.9e-07 29.2 0.0 4.3e-05 23.9 0.0 2.5 2 0 0 2 2 2 1 Arginyl tRNA synthetase N terminal domain Viral_env_E26 PF11050.3 CBZ53560.1 - 0.074 12.2 0.8 0.13 11.4 0.6 1.3 1 0 0 1 1 1 0 Virus envelope protein E26 DUF3926 PF13080.1 CBZ53561.1 - 0.0023 17.4 2.3 0.0055 16.2 1.6 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3926) Pkinase PF00069.20 CBZ53562.1 - 1.1e-76 257.3 0.0 1.5e-76 257.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ53562.1 - 2.6e-41 141.4 0.0 3.5e-41 141.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBZ53562.1 - 5.3e-07 28.8 0.0 9.8e-07 28.0 0.0 1.4 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.9 CBZ53562.1 - 0.0011 18.1 0.1 0.0017 17.4 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CBZ53562.1 - 0.0037 17.0 0.2 0.14 11.8 0.1 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 CBZ53562.1 - 0.004 16.5 0.7 0.0072 15.6 0.5 1.3 1 0 0 1 1 1 1 RIO1 family KaiB PF07689.7 CBZ53562.1 - 0.15 11.5 0.1 0.38 10.2 0.1 1.6 1 0 0 1 1 1 0 KaiB domain Choline_kinase PF01633.15 CBZ53562.1 - 0.25 10.8 0.3 0.46 10.0 0.2 1.4 1 1 0 1 1 1 0 Choline/ethanolamine kinase zf-RING_2 PF13639.1 CBZ53563.1 - 2.1e-11 43.4 13.7 3.3e-11 42.8 9.5 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 CBZ53563.1 - 7.4e-07 28.7 7.4 1.1e-06 28.1 5.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 CBZ53563.1 - 1.5e-06 28.1 6.4 2.7e-06 27.4 4.5 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 CBZ53563.1 - 7.2e-06 25.9 8.8 1.1e-05 25.3 6.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 CBZ53563.1 - 0.0024 17.6 4.2 0.0053 16.5 2.9 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.1 CBZ53563.1 - 0.0099 15.5 10.5 0.017 14.8 7.3 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 CBZ53563.1 - 0.018 14.7 2.6 0.035 13.8 1.8 1.5 1 0 0 1 1 1 0 RING-type zinc-finger zf-Nse PF11789.3 CBZ53563.1 - 0.064 12.7 1.3 0.11 12.0 0.9 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit RINGv PF12906.2 CBZ53563.1 - 0.12 12.3 8.3 0.24 11.4 5.8 1.5 1 0 0 1 1 1 0 RING-variant domain TniQ PF06527.6 CBZ53563.1 - 2.3 8.4 7.5 6.3 7.0 0.1 3.0 2 2 1 3 3 3 0 TniQ CAF1 PF04857.15 CBZ53564.1 - 9.4e-43 146.4 0.0 9.9e-39 133.2 0.0 2.3 1 1 1 2 2 2 2 CAF1 family ribonuclease V-ATPase_H_C PF11698.3 CBZ53564.1 - 0.1 12.5 0.0 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 V-ATPase subunit H LRR_4 PF12799.2 CBZ53565.1 - 1.2e-13 50.3 3.6 8.8e-08 31.6 0.1 3.5 1 1 2 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CBZ53565.1 - 5.2e-08 32.5 2.4 5.9e-07 29.1 0.2 2.3 1 1 1 2 2 2 2 Leucine rich repeat LRR_6 PF13516.1 CBZ53565.1 - 1e-07 31.2 0.1 0.016 15.1 0.0 3.6 3 0 0 3 3 3 2 Leucine Rich repeat LRR_7 PF13504.1 CBZ53565.1 - 2.7e-05 23.6 1.1 0.42 11.0 0.1 4.3 2 1 1 3 3 3 2 Leucine rich repeat LRR_1 PF00560.28 CBZ53565.1 - 4.7e-05 22.8 0.1 0.25 11.5 0.0 3.8 3 0 0 3 3 3 2 Leucine Rich Repeat LRR_9 PF14580.1 CBZ53565.1 - 0.0091 15.5 0.0 0.014 14.9 0.0 1.3 1 0 0 1 1 1 1 Leucine-rich repeat Hexapep PF00132.19 CBZ53568.1 - 1.1e-08 34.2 7.4 0.013 15.0 0.2 4.0 2 1 1 3 3 3 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 CBZ53568.1 - 0.11 12.1 8.9 0.35 10.4 0.7 3.1 3 0 0 3 3 3 0 Hexapeptide repeat of succinyl-transferase W2 PF02020.13 CBZ53568.1 - 0.13 12.2 0.0 0.13 12.2 0.0 1.9 2 0 0 2 2 2 0 eIF4-gamma/eIF5/eIF2-epsilon Matrix PF00661.16 CBZ53569.1 - 1.9 6.7 0.0 2.8 6.1 0.0 1.1 1 0 0 1 1 1 0 Viral matrix protein Kinase-like PF14531.1 CBZ53570.1 - 0.00019 20.5 0.0 0.00032 19.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Filament PF00038.16 CBZ53571.1 - 0.0055 16.2 14.4 0.0055 16.2 10.0 1.6 2 0 0 2 2 2 1 Intermediate filament protein Borrelia_P83 PF05262.6 CBZ53571.1 - 0.023 12.9 5.3 0.03 12.6 3.7 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Cob_adeno_trans PF01923.13 CBZ53571.1 - 0.047 13.4 4.3 0.062 13.0 1.4 2.1 2 0 0 2 2 2 0 Cobalamin adenosyltransferase AAA_13 PF13166.1 CBZ53571.1 - 0.18 10.2 4.8 0.28 9.6 3.3 1.2 1 0 0 1 1 1 0 AAA domain IncA PF04156.9 CBZ53571.1 - 0.35 10.4 19.0 0.015 14.8 7.6 2.3 2 0 0 2 2 2 0 IncA protein Mnd1 PF03962.10 CBZ53571.1 - 0.46 10.1 11.8 0.85 9.2 8.2 1.4 1 0 0 1 1 1 0 Mnd1 family OmpH PF03938.9 CBZ53571.1 - 1.8 8.4 11.4 3.4 7.5 7.9 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) APG6 PF04111.7 CBZ53571.1 - 2.4 7.1 11.9 4.5 6.2 8.2 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 Atg14 PF10186.4 CBZ53571.1 - 3.6 6.4 14.7 1.6 7.6 7.4 2.0 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 V_ATPase_I PF01496.14 CBZ53571.1 - 5.3 4.7 6.1 7.6 4.2 4.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family RRM_1 PF00076.17 CBZ53573.1 - 4.5e-08 32.6 0.0 1.4e-07 30.9 0.0 1.8 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBZ53573.1 - 1.4e-06 28.1 0.0 2.6e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBZ53573.1 - 0.045 13.6 0.0 0.077 12.8 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C3HC4_2 PF13923.1 CBZ53573.1 - 0.053 13.5 14.1 0.21 11.6 9.8 2.2 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBZ53573.1 - 0.17 11.5 13.5 0.73 9.6 8.3 2.8 1 1 1 2 2 2 0 zinc-RING finger domain zf-C3HC4 PF00097.20 CBZ53573.1 - 1.2 8.8 13.5 4.2 7.0 9.3 2.0 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) RabGAP-TBC PF00566.13 CBZ53574.1 - 1.2e-17 64.1 0.8 9.3e-14 51.3 0.0 3.9 3 1 0 3 3 3 2 Rab-GTPase-TBC domain Peptidase_M22 PF00814.20 CBZ53576.1 - 3e-34 118.7 1.0 4.6e-20 72.2 0.1 4.4 4 1 0 4 4 4 4 Glycoprotease family zf-Tim10_DDP PF02953.10 CBZ53578.1 - 2.5e-08 33.1 1.3 3.3e-08 32.7 0.9 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger ThiF PF00899.16 CBZ53580.1 - 4.5e-08 33.0 0.1 8.8e-08 32.0 0.1 1.5 1 0 0 1 1 1 1 ThiF family Mito_carr PF00153.22 CBZ53581.1 - 7.6e-61 201.8 0.2 4.3e-20 71.2 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein HMD PF03201.11 CBZ53581.1 - 0.12 12.2 0.0 9.3 6.2 0.0 2.8 3 0 0 3 3 3 0 H2-forming N5,N10-methylene-tetrahydromethanopterin dehydrogenase TSP_1 PF00090.14 CBZ53582.1 - 2.2e-36 123.7 61.9 4.6e-08 33.0 0.5 7.2 6 1 0 6 6 6 6 Thrombospondin type 1 domain VWA PF00092.23 CBZ53582.1 - 7.9e-36 123.4 0.0 1.2e-35 122.8 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.1 CBZ53582.1 - 8.1e-16 58.5 0.0 1.3e-15 57.9 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.1 CBZ53582.1 - 0.0017 18.0 0.0 0.003 17.2 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain RBM1CTR PF08081.6 CBZ53582.1 - 0.031 13.9 1.1 0.097 12.4 0.8 1.9 1 0 0 1 1 1 0 RBM1CTR (NUC064) family Copine PF07002.11 CBZ53582.1 - 0.068 12.9 0.0 0.25 11.0 0.0 1.8 2 0 0 2 2 2 0 Copine vWA-TerF-like PF10138.4 CBZ53582.1 - 0.11 12.3 0.0 0.16 11.7 0.0 1.2 1 0 0 1 1 1 0 vWA found in TerF C terminus DUF1136 PF06582.7 CBZ53584.1 - 0.0022 17.6 0.0 0.0064 16.1 0.0 1.9 1 0 0 1 1 1 1 Repeat of unknown function (DUF1136) Kinesin PF00225.18 CBZ53585.1 - 9.5e-35 119.8 0.0 1.1e-34 119.6 0.0 1.1 1 0 0 1 1 1 1 Kinesin motor domain Ran-binding PF05508.6 CBZ53586.1 - 2.4 7.0 0.0 3.6 6.4 0.0 1.1 1 0 0 1 1 1 0 RanGTP-binding protein FecCD PF01032.13 CBZ53587.1 - 1.7 7.3 0.4 2.9 6.6 0.3 1.2 1 0 0 1 1 1 0 FecCD transport family cobW PF02492.14 CBZ53588.1 - 2e-30 105.5 0.0 1.3e-29 102.8 0.0 2.0 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain T2SE PF00437.15 CBZ53588.1 - 0.043 12.7 0.4 0.77 8.6 0.0 2.4 3 0 0 3 3 3 0 Type II/IV secretion system protein UPF0079 PF02367.12 CBZ53588.1 - 0.085 12.4 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 CobW_C PF07683.9 CBZ53588.1 - 0.1 12.3 0.0 0.54 9.9 0.0 2.3 2 1 0 2 2 2 0 Cobalamin synthesis protein cobW C-terminal domain Miff PF05644.6 CBZ53588.1 - 2.2 7.8 7.0 3.9 7.0 4.9 1.3 1 0 0 1 1 1 0 Mitochondrial and peroxisomal fission factor Mff Phytase PF02333.10 CBZ53589.1 - 0.01 14.5 0.4 0.014 14.1 0.3 1.2 1 0 0 1 1 1 0 Phytase DUF1634 PF07843.6 CBZ53589.1 - 0.022 14.4 0.2 0.17 11.5 0.0 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1634) DUF3357 PF11837.3 CBZ53589.1 - 0.071 12.9 1.4 8.4 6.3 0.1 2.7 1 1 2 3 3 3 0 Domain of unknown function (DUF3357) tRNA_anti-like PF12869.2 CBZ53589.1 - 0.072 12.5 1.3 0.65 9.4 0.1 2.3 2 1 0 2 2 2 0 tRNA_anti-like CD99L2 PF12301.3 CBZ53589.1 - 9.8 5.8 9.6 0.36 10.4 0.5 2.6 2 1 1 3 3 3 0 CD99 antigen like protein 2 CorA PF01544.13 CBZ53590.1 - 0.00081 18.5 0.6 0.00081 18.5 0.4 1.8 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein DUF2231 PF09990.4 CBZ53590.1 - 0.22 11.8 2.5 0.43 10.9 1.8 1.5 1 0 0 1 1 1 0 Predicted membrane protein (DUF2231) Cpn10 PF00166.16 CBZ53591.1 - 1.3e-33 114.7 0.0 1.5e-18 66.4 0.0 2.0 2 0 0 2 2 2 2 Chaperonin 10 Kd subunit Rep_fac_C PF08542.6 CBZ53592.1 - 1.9e-09 37.3 0.1 9.8e-05 22.2 0.0 2.6 2 0 0 2 2 2 2 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 CBZ53592.1 - 3.8e-08 33.1 0.0 1.6e-07 31.1 0.0 2.0 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA_16 PF13191.1 CBZ53592.1 - 0.006 16.5 0.0 0.013 15.5 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain Rad17 PF03215.10 CBZ53592.1 - 0.014 14.0 0.0 0.018 13.7 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein SWIB PF02201.13 CBZ53594.1 - 4.5e-24 83.9 0.0 6e-24 83.5 0.0 1.2 1 0 0 1 1 1 1 SWIB/MDM2 domain Aldo_ket_red PF00248.16 CBZ53595.1 - 8.4e-40 136.3 0.0 1.2e-39 135.8 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family CoA_binding_2 PF13380.1 CBZ53595.1 - 0.039 14.1 0.0 6.6 6.9 0.0 2.9 3 0 0 3 3 3 0 CoA binding domain Arm PF00514.18 CBZ53596.1 - 2.8e-05 23.7 1.9 0.015 15.1 0.0 3.7 3 0 0 3 3 3 2 Armadillo/beta-catenin-like repeat DUF3361 PF11841.3 CBZ53596.1 - 0.11 12.2 2.5 0.17 11.5 0.5 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF3361) FAST_1 PF06743.10 CBZ53597.1 - 1.8e-07 30.7 0.2 0.35 10.5 0.0 3.6 2 1 1 3 3 3 3 FAST kinase-like protein, subdomain 1 SNF2_N PF00176.18 CBZ53598.1 - 4.6e-78 262.0 0.2 6.8e-78 261.4 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 CBZ53598.1 - 1.4e-15 56.9 0.0 4.4e-15 55.3 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 CBZ53598.1 - 5.8e-08 32.4 0.0 1.3e-07 31.2 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 CBZ53598.1 - 8.4e-07 28.9 4.0 9.3e-06 25.5 0.0 3.1 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.3 CBZ53598.1 - 9.8e-07 27.8 4.3 1.2e-06 27.5 0.0 2.6 2 1 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 Mem_trans PF03547.13 CBZ53598.1 - 8.4 4.5 5.3 15 3.7 3.7 1.3 1 0 0 1 1 1 0 Membrane transport protein Nucleoporin_FG PF13634.1 CBZ53600.1 - 2e-24 86.0 253.7 5.1e-07 29.9 31.5 7.3 1 1 6 7 7 7 6 Nucleoporin FG repeat region Nsp1_C PF05064.8 CBZ53600.1 - 4e-13 49.0 1.4 4e-13 49.0 1.0 1.7 2 0 0 2 2 2 1 Nsp1-like C-terminal region Cas_Csy4 PF09618.5 CBZ53600.1 - 0.12 12.1 0.8 0.2 11.4 0.5 1.2 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csy4) FTA4 PF13093.1 CBZ53600.1 - 0.22 10.9 3.1 0.33 10.3 2.1 1.2 1 0 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Brix PF04427.13 CBZ53601.1 - 5.2e-37 127.3 0.0 7.5e-37 126.8 0.0 1.2 1 0 0 1 1 1 1 Brix domain WD40 PF00400.27 CBZ53604.1 - 5.5e-10 38.7 15.7 3.4e-08 33.0 0.2 5.2 5 0 0 5 5 5 3 WD domain, G-beta repeat Nup160 PF11715.3 CBZ53604.1 - 0.014 13.5 0.0 0.041 12.0 0.0 1.7 2 0 0 2 2 2 0 Nucleoporin Nup120/160 Apc4_WD40 PF12894.2 CBZ53604.1 - 0.42 10.1 0.0 1.1 8.8 0.0 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain DUF1649 PF07855.7 CBZ53605.1 - 2.5e-05 24.0 0.0 0.0011 18.7 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1649) SNF2_N PF00176.18 CBZ53606.1 - 1.6e-18 66.5 0.0 2.9e-18 65.6 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain HNH PF01844.18 CBZ53606.1 - 7.6e-10 38.5 2.3 2e-09 37.1 1.6 1.8 1 0 0 1 1 1 1 HNH endonuclease zf-C4_Topoisom PF01396.14 CBZ53606.1 - 1.7e-07 30.6 2.9 4.4e-07 29.2 2.0 1.6 1 0 0 1 1 1 1 Topoisomerase DNA binding C4 zinc finger Helicase_C PF00271.26 CBZ53606.1 - 0.0019 18.0 0.0 0.0019 18.0 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 CBZ53606.1 - 0.0027 17.5 0.0 0.12 12.1 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.24 CBZ53606.1 - 0.5 9.8 0.3 41 3.6 0.0 3.0 3 0 0 3 3 3 0 DEAD/DEAH box helicase DUF2818 PF10993.3 CBZ53607.1 - 0.02 15.4 0.0 0.029 14.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2818) Peptidase_C48 PF02902.14 CBZ53607.1 - 0.035 13.7 0.2 0.045 13.3 0.1 1.1 1 0 0 1 1 1 0 Ulp1 protease family, C-terminal catalytic domain MscS_TM PF12794.2 CBZ53607.1 - 0.17 10.4 0.7 0.22 10.1 0.5 1.1 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 HSP70 PF00012.15 CBZ53608.1 - 1.7e-274 911.3 4.0 2e-274 911.1 2.7 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 CBZ53608.1 - 1.4e-14 53.4 0.3 1.2e-12 47.1 0.1 2.3 2 0 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.11 CBZ53608.1 - 8.3e-05 22.2 0.0 0.00034 20.2 0.0 2.0 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain DDR PF08841.5 CBZ53608.1 - 0.0021 16.9 1.3 0.33 9.7 0.3 2.3 2 0 0 2 2 2 2 Diol dehydratase reactivase ATPase-like domain Hydantoinase_A PF01968.13 CBZ53608.1 - 0.0071 15.4 0.1 0.034 13.2 0.1 2.0 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase FtsA PF14450.1 CBZ53608.1 - 0.024 14.4 3.0 0.64 9.8 0.0 3.2 2 1 0 2 2 2 0 Cell division protein FtsA DUF4483 PF14825.1 CBZ53609.1 - 4.1e-29 101.7 5.4 1.7e-27 96.4 3.8 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF4483) NTPase_P4 PF11602.3 CBZ53609.1 - 0.11 11.4 0.1 3.3 6.5 0.0 2.0 1 1 1 2 2 2 0 ATPase P4 of dsRNA bacteriophage phi-12 Thiolase_N PF00108.18 CBZ53610.1 - 8e-81 270.8 0.8 1.2e-80 270.3 0.6 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 CBZ53610.1 - 8.3e-23 80.1 0.1 2.3e-22 78.6 0.0 1.8 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 CBZ53610.1 - 0.0002 20.9 0.1 0.00065 19.2 0.0 1.8 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III_C PF08541.5 CBZ53610.1 - 0.07 13.1 0.2 0.29 11.1 0.0 2.2 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal Patatin PF01734.17 CBZ53611.1 - 3e-08 33.8 2.2 1.9e-07 31.2 1.5 2.2 1 1 0 1 1 1 1 Patatin-like phospholipase Glyco_hydro_3_C PF01915.17 CBZ53613.1 - 0.012 15.0 1.0 0.014 14.9 0.7 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 3 C-terminal domain FUSC PF04632.7 CBZ53613.1 - 1.4 7.2 5.8 1.6 7.0 4.0 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family Pkinase PF00069.20 CBZ53614.1 - 1.6e-47 161.8 0.0 2.3e-47 161.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ53614.1 - 1.1e-29 103.2 0.0 1.5e-29 102.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBZ53614.1 - 0.0098 14.8 0.0 0.016 14.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like AP2 PF00847.15 CBZ53616.1 - 0.0092 16.1 1.0 0.0092 16.1 0.7 2.3 2 0 0 2 2 2 1 AP2 domain DnaJ PF00226.26 CBZ53618.1 - 3e-21 74.9 0.5 5.8e-21 73.9 0.3 1.5 1 0 0 1 1 1 1 DnaJ domain HeLo PF14479.1 CBZ53618.1 - 0.2 11.3 0.6 0.4 10.4 0.1 1.6 1 1 1 2 2 2 0 Prion-inhibition and propagation SCIMP PF15050.1 CBZ53620.1 - 0.52 10.2 1.0 2.9 7.7 0.0 2.8 2 0 0 2 2 2 0 SCIMP protein DUF3510 PF12022.3 CBZ53621.1 - 9.1e-20 71.0 0.0 2.7e-19 69.4 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF3510) COG2 PF06148.6 CBZ53621.1 - 2.3e-08 34.0 1.0 7.5e-08 32.3 0.7 1.8 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 Vps51 PF08700.6 CBZ53621.1 - 6.1 6.7 5.6 0.98 9.3 0.1 2.5 2 1 1 3 3 3 0 Vps51/Vps67 Kinesin PF00225.18 CBZ53622.1 - 1.4e-92 309.9 0.3 2.4e-92 309.1 0.2 1.4 1 0 0 1 1 1 1 Kinesin motor domain Hrs_helical PF12210.3 CBZ53622.1 - 0.054 13.7 7.1 0.072 13.3 0.6 3.6 3 0 0 3 3 3 0 Hepatocyte growth factor-regulated tyrosine kinase substrate Reo_sigmaC PF04582.7 CBZ53622.1 - 3.5 6.7 10.6 0.25 10.4 1.1 2.5 2 1 2 4 4 4 0 Reovirus sigma C capsid protein SlyX PF04102.7 CBZ53622.1 - 7.3 7.0 20.8 0.031 14.6 1.3 5.3 5 0 0 5 5 5 0 SlyX O-FucT PF10250.4 CBZ53623.1 - 1.3e-31 109.9 0.0 9.5e-23 80.8 0.0 2.6 2 1 0 2 2 2 2 GDP-fucose protein O-fucosyltransferase PSS PF03034.10 CBZ53624.1 - 3.2e-59 200.6 10.0 4.3e-59 200.2 6.9 1.2 1 0 0 1 1 1 1 Phosphatidyl serine synthase Cyt-b5 PF00173.23 CBZ53625.1 - 7.3e-12 44.9 0.0 1.1e-11 44.3 0.0 1.5 1 1 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain PCI PF01399.22 CBZ53626.1 - 2.5e-11 43.8 0.0 5.4e-11 42.7 0.0 1.6 1 0 0 1 1 1 1 PCI domain CCDC-167 PF15188.1 CBZ53626.1 - 2.1 8.3 6.4 0.42 10.5 0.1 2.8 2 1 0 2 2 2 0 Coiled-coil domain-containing protein 167 TPR_1 PF00515.23 CBZ53628.1 - 3.1e-78 254.4 29.6 6.7e-11 41.3 0.0 10.9 10 0 0 10 10 10 9 Tetratricopeptide repeat TPR_11 PF13414.1 CBZ53628.1 - 8.2e-72 236.8 34.0 2.9e-14 52.4 0.0 7.8 3 1 2 7 7 7 7 TPR repeat TPR_17 PF13431.1 CBZ53628.1 - 2.7e-61 198.7 34.8 3.8e-07 29.7 0.0 11.5 11 0 0 11 11 11 10 Tetratricopeptide repeat TPR_2 PF07719.12 CBZ53628.1 - 1.1e-60 196.6 23.8 3.5e-07 29.6 0.1 10.8 11 0 0 11 11 10 9 Tetratricopeptide repeat TPR_12 PF13424.1 CBZ53628.1 - 1.1e-56 188.7 28.1 4.7e-12 45.6 0.1 7.0 1 1 8 9 9 9 8 Tetratricopeptide repeat Glyco_transf_41 PF13844.1 CBZ53628.1 - 2.5e-47 160.9 0.1 1e-22 79.8 0.1 2.1 2 0 0 2 2 2 2 Glycosyl transferase family 41 TPR_8 PF13181.1 CBZ53628.1 - 2.7e-42 139.3 14.4 3e-06 26.6 0.0 10.3 10 0 0 10 10 10 6 Tetratricopeptide repeat TPR_16 PF13432.1 CBZ53628.1 - 2.5e-38 129.9 17.6 1.9e-08 34.7 0.6 8.1 4 3 4 9 9 8 7 Tetratricopeptide repeat TPR_7 PF13176.1 CBZ53628.1 - 2.1e-35 117.7 9.8 7.3e-05 22.2 0.0 11.4 12 0 0 12 12 11 7 Tetratricopeptide repeat TPR_14 PF13428.1 CBZ53628.1 - 7.6e-35 116.2 7.9 0.0029 18.1 0.0 11.2 3 2 9 12 12 11 8 Tetratricopeptide repeat TPR_10 PF13374.1 CBZ53628.1 - 8.8e-28 95.4 25.4 0.0031 17.3 0.0 10.8 11 0 0 11 11 11 8 Tetratricopeptide repeat TPR_19 PF14559.1 CBZ53628.1 - 4.2e-23 81.4 13.8 0.001 19.3 0.0 8.0 3 3 3 8 8 8 6 Tetratricopeptide repeat EST1_DNA_bind PF10373.4 CBZ53628.1 - 9.3e-14 51.2 12.8 1.1e-05 24.8 0.1 4.9 3 2 1 4 4 4 3 Est1 DNA/RNA binding domain TPR_9 PF13371.1 CBZ53628.1 - 6.9e-13 48.2 5.6 0.097 12.5 1.0 5.5 4 1 1 5 5 5 5 Tetratricopeptide repeat TPR_6 PF13174.1 CBZ53628.1 - 3.7e-12 45.8 5.5 0.27 11.7 0.0 8.1 9 0 0 9 9 7 2 Tetratricopeptide repeat Apc3 PF12895.2 CBZ53628.1 - 3.4e-09 36.7 18.4 0.00089 19.3 0.4 5.3 4 1 1 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 Coatomer_E PF04733.9 CBZ53628.1 - 3.8e-09 36.1 2.1 0.0042 16.3 0.0 3.8 1 1 2 4 4 4 2 Coatomer epsilon subunit NARP1 PF12569.3 CBZ53628.1 - 1e-07 31.1 3.6 0.27 9.9 0.1 4.0 2 1 2 4 4 4 3 NMDA receptor-regulated protein 1 TPR_15 PF13429.1 CBZ53628.1 - 1.1e-06 27.9 2.0 0.076 12.0 0.0 4.5 1 1 4 5 5 5 3 Tetratricopeptide repeat TPR_4 PF07721.9 CBZ53628.1 - 1.6e-06 27.9 0.1 8.5 7.1 0.0 6.9 9 0 0 9 9 5 0 Tetratricopeptide repeat TPR_5 PF12688.2 CBZ53628.1 - 5.3e-05 23.2 0.7 0.028 14.4 0.0 3.6 2 1 1 3 3 3 1 Tetratrico peptide repeat TOM20_plant PF06552.7 CBZ53628.1 - 0.0013 18.3 1.4 0.8 9.2 0.3 4.5 1 1 4 5 5 5 1 Plant specific mitochondrial import receptor subunit TOM20 Rapsyn_N PF10579.4 CBZ53628.1 - 0.0015 18.3 0.0 0.23 11.3 0.0 3.2 2 1 1 3 3 3 1 Rapsyn N-terminal myristoylation and linker region FAT PF02259.18 CBZ53628.1 - 0.0036 16.3 0.5 5 6.0 0.0 3.6 1 1 2 3 3 3 1 FAT domain MIT PF04212.13 CBZ53628.1 - 0.15 11.9 20.4 1.8 8.5 0.1 7.8 8 2 1 9 9 8 0 MIT (microtubule interacting and transport) domain BTAD PF03704.12 CBZ53628.1 - 0.26 11.5 10.0 21 5.4 1.8 4.8 3 1 3 6 6 6 0 Bacterial transcriptional activator domain RPN7 PF10602.4 CBZ53628.1 - 0.32 10.3 2.6 5.8 6.2 0.0 4.0 2 2 3 5 5 5 0 26S proteasome subunit RPN7 Fis1_TPR_C PF14853.1 CBZ53628.1 - 7 6.6 10.6 4.4 7.2 0.0 4.8 6 0 0 6 6 4 0 Fis1 C-terminal tetratricopeptide repeat Gln-synt_C PF00120.19 CBZ53629.1 - 6.6e-92 307.3 0.0 8.3e-92 306.9 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.14 CBZ53629.1 - 2.4e-16 59.0 0.2 4.5e-16 58.1 0.2 1.4 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain Dynein_heavy PF03028.10 CBZ53630.1 - 4.9e-210 699.2 0.0 8.2e-210 698.4 0.0 1.4 1 0 0 1 1 1 1 Dynein heavy chain and region D6 of dynein motor DHC_N2 PF08393.8 CBZ53630.1 - 3.3e-112 374.9 3.9 5.3e-112 374.3 0.0 3.0 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 2 AAA_6 PF12774.2 CBZ53630.1 - 8e-96 320.0 0.0 2.1e-95 318.6 0.0 1.8 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region D1 MT PF12777.2 CBZ53630.1 - 5.9e-53 179.8 11.7 1.3e-52 178.6 8.1 1.6 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_8 PF12780.2 CBZ53630.1 - 4e-49 167.0 0.0 5.3e-44 150.1 0.0 2.8 2 1 0 2 2 2 2 P-loop containing dynein motor region D4 AAA_9 PF12781.2 CBZ53630.1 - 5.3e-49 166.1 1.9 8.5e-49 165.4 0.0 2.4 4 0 0 4 4 4 1 ATP-binding dynein motor region D5 AAA_7 PF12775.2 CBZ53630.1 - 7.4e-37 126.8 0.0 1.6e-36 125.7 0.0 1.6 1 0 0 1 1 1 1 P-loop containing dynein motor region D3 AAA_5 PF07728.9 CBZ53630.1 - 4.9e-16 58.7 0.0 9e-05 22.2 0.0 6.4 5 1 0 5 5 5 3 AAA domain (dynein-related subfamily) AAA PF00004.24 CBZ53630.1 - 8.1e-07 29.3 0.7 0.16 12.2 0.0 4.0 4 0 0 4 4 4 2 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 CBZ53630.1 - 0.00038 20.1 3.1 2.8 7.7 0.0 3.9 3 0 0 3 3 3 2 Part of AAA domain AAA_17 PF13207.1 CBZ53630.1 - 0.0011 19.8 0.4 0.11 13.3 0.0 3.7 3 0 0 3 3 2 1 AAA domain DUF853 PF05872.7 CBZ53630.1 - 0.0029 16.0 1.8 0.56 8.4 0.0 2.7 3 0 0 3 3 3 2 Bacterial protein of unknown function (DUF853) AAA_18 PF13238.1 CBZ53630.1 - 0.012 15.9 1.7 3.8 7.8 0.0 4.7 5 0 0 5 5 4 0 AAA domain AAA_14 PF13173.1 CBZ53630.1 - 0.025 14.4 0.0 11 5.9 0.0 3.6 4 0 0 4 4 2 0 AAA domain T2SE PF00437.15 CBZ53630.1 - 0.03 13.2 0.4 1.2 8.0 0.0 2.9 3 0 0 3 3 3 0 Type II/IV secretion system protein AAA_22 PF13401.1 CBZ53630.1 - 0.035 14.2 3.8 5.6 7.1 0.0 4.9 5 0 0 5 5 4 0 AAA domain FtsK_SpoIIIE PF01580.13 CBZ53630.1 - 0.068 12.6 1.3 0.54 9.6 0.0 2.9 3 0 0 3 3 3 0 FtsK/SpoIIIE family AAA_29 PF13555.1 CBZ53630.1 - 0.11 11.9 2.9 0.39 10.2 0.1 3.0 3 0 0 3 3 3 0 P-loop containing region of AAA domain RNA_helicase PF00910.17 CBZ53630.1 - 0.48 10.6 0.0 72 3.6 0.0 3.3 3 0 0 3 3 3 0 RNA helicase AAA_33 PF13671.1 CBZ53630.1 - 0.74 9.6 5.0 6.7 6.5 0.0 3.8 4 0 0 4 4 3 0 AAA domain Trichoplein PF13868.1 CBZ53631.1 - 4.8e-12 44.9 139.5 4.8e-12 44.9 96.7 2.8 2 1 0 2 2 2 1 Tumour suppressor, Mitostatin DUF4028 PF13220.1 CBZ53631.1 - 0.032 13.8 0.4 0.16 11.6 0.3 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4028) Paf67 PF10255.4 CBZ53632.1 - 9.9e-129 429.7 14.8 1.2e-128 429.4 10.3 1.1 1 0 0 1 1 1 1 RNA polymerase I-associated factor PAF67 UPF0051 PF01458.12 CBZ53633.1 - 2.2e-46 158.1 0.0 5.7e-46 156.8 0.0 1.7 1 1 0 1 1 1 1 Uncharacterized protein family (UPF0051) tRNA-synt_1b PF00579.20 CBZ53635.1 - 4.3e-36 124.5 0.0 1.2e-16 60.7 0.0 3.4 3 1 0 3 3 3 3 tRNA synthetases class I (W and Y) S4 PF01479.20 CBZ53635.1 - 2.2e-06 27.0 0.2 5.2e-06 25.7 0.1 1.6 1 0 0 1 1 1 1 S4 domain DUF4427 PF14468.1 CBZ53636.1 - 0.12 12.0 0.0 0.19 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4427) Mito_carr PF00153.22 CBZ53637.1 - 7.8e-55 182.5 4.7 5e-18 64.6 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein YiaAB PF05360.9 CBZ53637.1 - 0.0085 15.6 1.9 0.011 15.2 0.3 1.9 2 0 0 2 2 2 1 yiaA/B two helix domain DUF1510 PF07423.6 CBZ53638.1 - 7.4 5.8 50.3 9.2 5.5 34.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Ion_trans_2 PF07885.11 CBZ53639.1 - 2.4e-10 39.9 1.7 2.4e-10 39.9 1.2 2.3 2 0 0 2 2 2 1 Ion channel BK_channel_a PF03493.13 CBZ53639.1 - 2.7e-10 40.0 0.0 5e-09 36.0 0.0 2.5 2 0 0 2 2 2 1 Calcium-activated BK potassium channel alpha subunit Ion_trans PF00520.26 CBZ53639.1 - 6.8e-06 25.4 1.5 6.8e-06 25.4 1.1 1.7 1 1 1 2 2 2 1 Ion transport protein Mitochondr_Som1 PF11093.3 CBZ53639.1 - 0.8 9.5 0.0 1.7 8.4 0.0 1.5 1 0 0 1 1 1 0 Mitochondrial export protein Som1 DUF4044 PF13253.1 CBZ53639.1 - 5.3 6.2 5.5 10 5.3 3.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4044) Adaptin_N PF01602.15 CBZ53640.1 - 2.5e-86 290.0 1.3 3.2e-86 289.7 0.9 1.1 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.5 CBZ53640.1 - 2e-29 102.3 0.0 3.9e-29 101.4 0.0 1.5 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain HEAT_2 PF13646.1 CBZ53640.1 - 6.7e-10 39.1 15.4 0.0018 18.5 0.1 6.0 3 2 0 4 4 4 3 HEAT repeats HEAT PF02985.17 CBZ53640.1 - 0.0021 17.9 18.2 0.96 9.7 0.0 8.0 10 0 0 10 10 10 1 HEAT repeat HEAT_EZ PF13513.1 CBZ53640.1 - 0.047 14.1 14.3 0.16 12.5 0.2 6.3 6 0 0 6 6 6 0 HEAT-like repeat ABC_tran PF00005.22 CBZ53641.1 - 4.5e-31 107.9 0.0 7.4e-31 107.2 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.18 CBZ53641.1 - 4.3e-22 78.8 5.4 7e-22 78.1 3.8 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.14 CBZ53641.1 - 0.00025 20.3 0.0 0.0019 17.4 0.0 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 CBZ53641.1 - 0.00055 19.9 0.0 0.0016 18.4 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 CBZ53641.1 - 0.0034 18.2 0.0 0.011 16.5 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 CBZ53641.1 - 0.0051 17.1 0.1 0.011 15.9 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.1 CBZ53641.1 - 0.0059 16.1 0.0 0.013 14.9 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.1 CBZ53641.1 - 0.0061 16.5 0.0 1.8 8.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 CBZ53641.1 - 0.027 13.9 0.0 0.05 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain DUF87 PF01935.12 CBZ53641.1 - 0.038 13.8 0.1 0.072 12.8 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function DUF87 AAA_33 PF13671.1 CBZ53641.1 - 0.049 13.5 0.0 0.16 11.8 0.0 1.9 1 0 0 1 1 1 0 AAA domain DUF258 PF03193.11 CBZ53641.1 - 0.12 11.5 0.0 0.24 10.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Anoctamin PF04547.7 CBZ53641.1 - 0.16 10.5 6.4 0.26 9.9 4.5 1.2 1 0 0 1 1 1 0 Calcium-activated chloride channel MobB PF03205.9 CBZ53641.1 - 0.18 11.5 0.1 0.32 10.7 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_24 PF13479.1 CBZ53641.1 - 0.32 10.5 0.7 9.1 5.8 0.3 2.2 2 0 0 2 2 2 0 AAA domain Potyvirid-P3 PF13608.1 CBZ53641.1 - 1.4 7.9 3.5 0.45 9.5 0.5 1.6 2 0 0 2 2 2 0 Protein P3 of Potyviral polyprotein PT PF04886.7 CBZ53641.1 - 2.3 7.5 27.1 0.024 13.9 12.2 2.4 2 0 0 2 2 2 0 PT repeat MoaE PF02391.12 CBZ53642.1 - 4.3e-10 39.4 0.2 9.6e-10 38.3 0.1 1.6 1 1 1 2 2 2 1 MoaE protein Phage_coat PF09063.5 CBZ53642.1 - 0.0051 16.5 0.0 0.013 15.2 0.1 1.6 2 0 0 2 2 2 1 Phage PP7 coat protein DUF2730 PF10805.3 CBZ53643.1 - 0.23 11.2 2.3 2.7 7.7 0.0 3.5 3 1 1 4 4 4 0 Protein of unknown function (DUF2730) Syntaxin-6_N PF09177.6 CBZ53643.1 - 2.3 8.6 9.2 28 5.2 1.0 4.0 1 1 2 4 4 4 0 Syntaxin 6, N-terminal Phage_Coat_Gp8 PF05371.7 CBZ53643.1 - 2.6 7.6 6.2 19 4.9 0.1 3.6 4 0 0 4 4 4 0 Phage major coat protein, Gp8 ATG16 PF08614.6 CBZ53643.1 - 4.6 7.0 16.3 4.3 7.1 6.9 2.5 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) HemY_N PF07219.8 CBZ53645.1 - 0.0029 17.1 0.2 0.0045 16.5 0.2 1.2 1 0 0 1 1 1 1 HemY protein N-terminus Mpv17_PMP22 PF04117.7 CBZ53647.1 - 8.1e-15 54.2 2.5 8.1e-15 54.2 1.7 1.7 2 0 0 2 2 2 1 Mpv17 / PMP22 family Macoilin PF09726.4 CBZ53648.1 - 2 6.5 5.3 2 6.5 3.7 1.1 1 0 0 1 1 1 0 Transmembrane protein Solute_trans_a PF03619.11 CBZ53649.1 - 1.3e-42 145.9 13.4 5.8e-23 81.5 1.8 3.9 3 1 1 4 4 4 3 Organic solute transporter Ostalpha zf-C3HC4 PF00097.20 CBZ53650.1 - 0.00023 20.7 9.2 0.00039 20.0 6.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 CBZ53650.1 - 0.0036 17.1 9.2 0.0079 16.0 6.4 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.1 CBZ53650.1 - 0.013 15.1 7.8 0.023 14.3 5.4 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CBZ53650.1 - 0.027 14.4 10.6 0.049 13.6 7.3 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBZ53650.1 - 0.15 11.8 9.8 0.27 10.9 6.8 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_6 PF14835.1 CBZ53650.1 - 0.24 11.1 5.9 0.45 10.3 4.1 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_2 PF13639.1 CBZ53650.1 - 0.58 10.0 9.8 1.1 9.1 6.8 1.5 1 0 0 1 1 1 0 Ring finger domain Radical_SAM PF04055.16 CBZ53651.1 - 4.6e-17 62.6 0.0 1.3e-16 61.1 0.0 1.8 2 0 0 2 2 2 1 Radical SAM superfamily UPF0004 PF00919.15 CBZ53651.1 - 4e-16 58.6 0.3 1.6e-15 56.7 0.1 2.1 2 0 0 2 2 2 1 Uncharacterized protein family UPF0004 SAG PF04092.8 CBZ53652.1 - 1.1e-39 135.6 27.6 2.8e-27 95.5 5.0 2.6 3 0 0 3 3 3 2 SRS domain SAG PF04092.8 CBZ53653.1 - 2.9e-37 127.7 30.3 1.7e-26 93.0 6.9 2.2 2 0 0 2 2 2 2 SRS domain SAG PF04092.8 CBZ53654.1 - 4.5e-39 133.6 24.3 2.3e-28 99.0 4.7 2.1 2 0 0 2 2 2 2 SRS domain SAG PF04092.8 CBZ53655.1 - 2.1e-39 134.7 26.2 4.6e-28 98.0 5.0 2.2 2 0 0 2 2 2 2 SRS domain SAG PF04092.8 CBZ53656.1 - 1.6e-37 128.6 27.6 1.1e-26 93.6 5.5 2.1 2 0 0 2 2 2 2 SRS domain SAG PF04092.8 CBZ53657.1 - 4.1e-62 208.0 33.1 2.7e-27 95.6 3.6 3.1 3 0 0 3 3 3 3 SRS domain Cadherin-like PF12733.2 CBZ53657.1 - 0.37 11.0 7.2 2.7 8.3 0.3 3.7 3 1 0 3 3 3 0 Cadherin-like beta sandwich domain SAG PF04092.8 CBZ53658.1 - 1.1e-37 129.2 25.1 1.9e-27 96.1 3.5 2.1 2 0 0 2 2 2 2 SRS domain SAG PF04092.8 CBZ53659.1 - 3.5e-39 134.0 19.4 3.6e-28 98.4 4.9 2.2 2 0 0 2 2 2 2 SRS domain Cortexin PF11057.3 CBZ53659.1 - 0.13 11.8 0.0 0.34 10.5 0.0 1.7 1 0 0 1 1 1 0 Cortexin of kidney SAG PF04092.8 CBZ53660.1 - 1.5e-38 131.9 23.9 2.9e-27 95.5 4.3 2.2 2 0 0 2 2 2 2 SRS domain SAG PF04092.8 CBZ53661.1 - 2.5e-39 134.4 23.1 1.6e-26 93.0 3.6 2.1 2 0 0 2 2 2 2 SRS domain SAG PF04092.8 CBZ53662.1 - 4.7e-40 136.8 27.6 1.2e-27 96.7 4.2 2.2 2 0 0 2 2 2 2 SRS domain DNA_pol_A_exo1 PF01612.15 CBZ53663.1 - 4.3e-22 78.4 0.0 6.4e-22 77.8 0.0 1.2 1 0 0 1 1 1 1 3'-5' exonuclease AAA PF00004.24 CBZ53664.1 - 1.3e-94 313.4 0.0 8e-47 158.7 0.0 2.6 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 CBZ53664.1 - 1.5e-13 50.3 0.0 6.8e-06 25.3 0.0 3.0 2 1 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 CBZ53664.1 - 6.1e-13 49.0 0.2 2.7e-05 24.3 0.0 4.1 2 2 0 3 3 3 2 AAA domain AAA_17 PF13207.1 CBZ53664.1 - 1.2e-12 48.6 0.0 7.2e-06 26.8 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 CBZ53664.1 - 2.5e-12 47.1 1.3 7.9e-05 22.7 0.0 3.7 3 2 0 3 3 2 2 AAA ATPase domain AAA_33 PF13671.1 CBZ53664.1 - 2.9e-12 46.6 0.0 7.9e-06 25.7 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.9 CBZ53664.1 - 1.1e-11 44.5 0.1 8.6e-06 25.5 0.0 3.5 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 CBZ53664.1 - 1.6e-11 44.3 0.0 1e-06 28.7 0.0 2.8 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_14 PF13173.1 CBZ53664.1 - 1.8e-09 37.5 0.0 0.00016 21.5 0.0 2.4 2 0 0 2 2 2 2 AAA domain TIP49 PF06068.8 CBZ53664.1 - 6.1e-09 35.0 0.0 0.00058 18.6 0.0 2.3 2 0 0 2 2 2 2 TIP49 C-terminus AAA_25 PF13481.1 CBZ53664.1 - 6.3e-09 35.5 2.1 0.053 12.9 0.0 3.7 2 2 2 4 4 4 3 AAA domain Zeta_toxin PF06414.7 CBZ53664.1 - 2.2e-08 33.4 0.0 0.003 16.6 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin AAA_18 PF13238.1 CBZ53664.1 - 1.4e-07 31.8 0.0 0.012 15.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.16 CBZ53664.1 - 2.2e-07 30.2 0.2 0.022 13.9 0.0 2.6 3 0 0 3 3 2 2 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 CBZ53664.1 - 2.4e-07 30.9 0.0 0.009 16.1 0.0 2.7 3 0 0 3 3 2 2 RNA helicase IstB_IS21 PF01695.12 CBZ53664.1 - 6.8e-07 28.8 0.0 0.033 13.5 0.0 2.3 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_19 PF13245.1 CBZ53664.1 - 1.1e-06 28.3 3.3 0.012 15.3 0.4 2.9 3 0 0 3 3 2 2 Part of AAA domain Arch_ATPase PF01637.13 CBZ53664.1 - 1.6e-06 28.0 0.1 0.027 14.1 0.0 3.3 2 2 2 4 4 3 2 Archaeal ATPase Sigma54_activ_2 PF14532.1 CBZ53664.1 - 1.8e-06 28.0 0.0 0.022 14.7 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_28 PF13521.1 CBZ53664.1 - 1.9e-06 27.9 0.1 0.073 13.0 0.0 2.7 3 0 0 3 3 2 2 AAA domain NACHT PF05729.7 CBZ53664.1 - 2.4e-06 27.3 0.0 0.28 10.8 0.0 3.9 3 1 0 4 4 4 2 NACHT domain KaiC PF06745.8 CBZ53664.1 - 1.4e-05 24.3 0.1 1.8 7.6 0.0 3.3 2 1 1 3 3 3 2 KaiC AAA_24 PF13479.1 CBZ53664.1 - 1.7e-05 24.5 0.1 0.21 11.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain ABC_tran PF00005.22 CBZ53664.1 - 1.9e-05 24.9 0.0 0.17 12.1 0.0 2.9 2 1 0 2 2 2 2 ABC transporter Viral_helicase1 PF01443.13 CBZ53664.1 - 2.3e-05 24.0 0.0 0.0046 16.4 0.0 2.3 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase NB-ARC PF00931.17 CBZ53664.1 - 3.9e-05 22.6 0.2 0.2 10.4 0.0 2.7 3 0 0 3 3 3 2 NB-ARC domain ResIII PF04851.10 CBZ53664.1 - 4.7e-05 23.2 0.0 0.009 15.8 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Vps4_C PF09336.5 CBZ53664.1 - 8.1e-05 22.4 0.1 0.0011 18.8 0.0 2.4 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain Parvo_NS1 PF01057.12 CBZ53664.1 - 8.5e-05 21.5 0.0 0.3 9.9 0.0 2.2 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 Sigma54_activat PF00158.21 CBZ53664.1 - 0.00016 21.1 0.0 0.92 8.9 0.0 3.6 2 2 0 2 2 2 1 Sigma-54 interaction domain NTPase_1 PF03266.10 CBZ53664.1 - 0.00021 21.0 0.3 1 9.0 0.0 3.6 2 1 0 3 3 3 1 NTPase PhoH PF02562.11 CBZ53664.1 - 0.00069 18.8 0.2 0.73 9.0 0.0 2.4 2 0 0 2 2 2 2 PhoH-like protein AAA_3 PF07726.6 CBZ53664.1 - 0.00074 19.1 0.0 1.2 8.7 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Bac_DnaA PF00308.13 CBZ53664.1 - 0.00078 19.1 0.0 0.55 9.8 0.0 2.5 2 0 0 2 2 2 1 Bacterial dnaA protein DUF815 PF05673.8 CBZ53664.1 - 0.001 18.0 0.0 0.58 9.0 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF815) Cytidylate_kin2 PF13189.1 CBZ53664.1 - 0.0017 18.2 0.0 0.31 10.9 0.0 2.4 2 0 0 2 2 2 1 Cytidylate kinase-like family SKI PF01202.17 CBZ53664.1 - 0.003 17.4 0.0 2.8 7.7 0.0 2.5 2 0 0 2 2 2 0 Shikimate kinase DUF2075 PF09848.4 CBZ53664.1 - 0.0037 16.2 0.0 0.68 8.8 0.0 2.3 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) UPF0079 PF02367.12 CBZ53664.1 - 0.0054 16.3 0.1 3.8 7.1 0.0 3.0 3 0 0 3 3 3 0 Uncharacterised P-loop hydrolase UPF0079 KAP_NTPase PF07693.9 CBZ53664.1 - 0.0059 15.6 0.1 1.6 7.6 0.0 3.3 2 2 2 4 4 4 1 KAP family P-loop domain AAA_10 PF12846.2 CBZ53664.1 - 0.0081 15.6 0.8 4.7 6.5 0.0 3.2 3 0 0 3 3 3 0 AAA-like domain AAA_30 PF13604.1 CBZ53664.1 - 0.0085 15.6 0.0 5.7 6.4 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.1 CBZ53664.1 - 0.019 15.3 0.0 5 7.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain DEAD PF00270.24 CBZ53664.1 - 0.032 13.7 0.1 15 4.9 0.0 3.3 2 1 0 3 3 3 0 DEAD/DEAH box helicase AAA_29 PF13555.1 CBZ53664.1 - 0.033 13.7 0.0 3.4 7.2 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_11 PF13086.1 CBZ53664.1 - 0.051 13.1 0.0 9.8 5.6 0.0 2.3 2 1 0 2 2 2 0 AAA domain Zot PF05707.7 CBZ53664.1 - 0.058 12.8 0.4 4.2 6.7 0.1 3.0 2 1 0 2 2 2 0 Zonular occludens toxin (Zot) KTI12 PF08433.5 CBZ53664.1 - 0.067 12.3 0.0 4.2 6.5 0.0 2.3 2 0 0 2 2 2 0 Chromatin associated protein KTI12 T2SE PF00437.15 CBZ53664.1 - 0.098 11.5 0.0 9.9 4.9 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein Rad17 PF03215.10 CBZ53664.1 - 0.1 11.2 0.0 3.7 6.1 0.0 2.2 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein AAA_21 PF13304.1 CBZ53664.1 - 0.11 12.4 0.3 20 5.0 0.0 3.4 4 0 0 4 4 3 0 AAA domain CPSase_L_D3 PF02787.14 CBZ53664.1 - 0.15 11.8 0.1 0.72 9.6 0.0 2.0 2 0 0 2 2 2 0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain DAP3 PF10236.4 CBZ53664.1 - 0.16 10.8 0.0 16 4.3 0.0 2.4 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 CDC48_N PF02359.13 CBZ53665.1 - 1.9e-25 88.6 0.3 3e-25 87.9 0.2 1.3 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain CDC48_2 PF02933.12 CBZ53665.1 - 0.00059 19.4 0.0 0.0012 18.4 0.0 1.5 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 eIF-1a PF01176.14 CBZ53665.1 - 0.022 14.1 1.7 4 6.9 0.3 3.1 1 1 1 2 2 2 0 Translation initiation factor 1A / IF-1 Molydop_binding PF01568.16 CBZ53665.1 - 0.044 13.5 0.1 0.24 11.2 0.0 2.0 1 1 1 2 2 2 0 Molydopterin dinucleotide binding domain S4 PF01479.20 CBZ53665.1 - 0.053 12.9 0.5 0.11 11.9 0.4 1.5 1 0 0 1 1 1 0 S4 domain ArfGap PF01412.13 CBZ53666.1 - 2.8e-30 104.4 0.1 6.8e-30 103.2 0.1 1.6 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf RIIa PF02197.12 CBZ53666.1 - 0.002 17.5 0.0 0.0049 16.2 0.0 1.6 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit Ribosomal_S17 PF00366.15 CBZ53667.1 - 1.3e-12 47.5 0.2 1.9e-12 47.0 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S17 KAR9 PF08580.5 CBZ53668.1 - 0.24 9.6 0.4 0.38 8.9 0.3 1.2 1 0 0 1 1 1 0 Yeast cortical protein KAR9 His_Phos_1 PF00300.17 CBZ53670.1 - 1.2e-38 132.6 0.0 1.7e-38 132.2 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Cpn60_TCP1 PF00118.19 CBZ53671.1 - 1.1e-144 482.6 9.0 1.3e-144 482.4 6.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Phage_tail_X PF05489.7 CBZ53671.1 - 0.067 12.6 0.0 0.21 11.1 0.0 1.8 1 0 0 1 1 1 0 Phage Tail Protein X Rad51 PF08423.6 CBZ53672.1 - 5.4e-129 428.5 0.1 1.1e-128 427.6 0.0 1.5 2 0 0 2 2 2 1 Rad51 AAA_25 PF13481.1 CBZ53672.1 - 1.7e-12 47.1 0.0 3e-12 46.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain RecA PF00154.16 CBZ53672.1 - 4.2e-09 35.8 0.0 6.2e-09 35.3 0.0 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein KaiC PF06745.8 CBZ53672.1 - 7.9e-06 25.1 0.0 1.7e-05 24.0 0.0 1.6 2 0 0 2 2 2 1 KaiC HHH_5 PF14520.1 CBZ53672.1 - 7.2e-05 22.8 0.4 0.00018 21.6 0.1 1.8 2 0 0 2 2 2 1 Helix-hairpin-helix domain AAA_22 PF13401.1 CBZ53672.1 - 0.084 13.0 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain RRM_6 PF14259.1 CBZ53673.1 - 1.2e-14 53.9 0.0 1.5e-06 28.0 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CBZ53673.1 - 9.4e-14 50.8 0.1 1.7e-06 27.5 0.0 4.0 4 0 0 4 4 4 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBZ53673.1 - 1.6e-07 31.0 0.0 0.0079 16.0 0.0 3.2 4 0 0 4 4 4 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CTD_bind PF04818.8 CBZ53675.1 - 0.03 14.5 0.1 0.25 11.6 0.1 2.6 2 1 0 2 2 2 0 RNA polymerase II-binding domain. Sec3_C_2 PF15278.1 CBZ53675.1 - 0.14 12.2 0.8 3 8.0 0.1 2.5 2 0 0 2 2 2 0 Sec3 exocyst complex subunit RNA_pol_Rpb2_6 PF00562.23 CBZ53676.1 - 1.4e-111 372.9 0.0 3.2e-111 371.7 0.0 1.6 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 CBZ53676.1 - 1.6e-44 151.3 0.0 2.3e-44 150.7 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_7 PF04560.15 CBZ53676.1 - 1.4e-27 95.7 0.1 3.8e-27 94.3 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_4 PF04566.8 CBZ53676.1 - 5e-22 77.4 0.7 1.3e-21 76.1 0.5 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_2 PF04561.9 CBZ53676.1 - 9e-21 74.1 0.0 2.6e-20 72.6 0.0 1.8 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_3 PF04565.11 CBZ53676.1 - 3.5e-20 71.5 0.0 6.2e-20 70.7 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.12 CBZ53676.1 - 2.7e-10 40.0 0.2 5.3e-10 39.1 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 Pox_MCEL PF03291.11 CBZ53678.1 - 1.4e-35 122.8 0.0 1.6e-27 96.2 0.0 2.7 2 1 0 2 2 2 2 mRNA capping enzyme Methyltransf_18 PF12847.2 CBZ53678.1 - 5.2e-08 33.4 0.1 1.8e-07 31.7 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 CBZ53678.1 - 5.4e-08 33.2 0.3 1.8e-07 31.5 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 CBZ53678.1 - 2.5e-07 30.9 0.1 6.8e-07 29.5 0.1 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CBZ53678.1 - 1.3e-06 28.7 0.0 4e-06 27.2 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CBZ53678.1 - 3.4e-06 26.8 0.0 8.5e-06 25.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 CBZ53678.1 - 6.1e-05 23.0 0.1 0.00016 21.6 0.1 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CBZ53678.1 - 0.00016 21.2 0.0 0.00036 20.1 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 CBZ53678.1 - 0.051 12.6 0.0 0.098 11.7 0.0 1.4 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.13 CBZ53678.1 - 0.26 10.3 0.0 0.42 9.6 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family AP2 PF00847.15 CBZ53679.1 - 1.3e-08 34.8 0.1 1.3e-08 34.8 0.1 2.0 2 0 0 2 2 2 1 AP2 domain DUF2158 PF09926.4 CBZ53679.1 - 0.82 9.1 1.3 1.5 8.3 0.1 2.0 2 0 0 2 2 2 0 Uncharacterized small protein (DUF2158) STAS_2 PF13466.1 CBZ53680.1 - 0.046 13.7 0.1 0.15 12.1 0.1 1.8 1 0 0 1 1 1 0 STAS domain PBP1_TM PF14812.1 CBZ53681.1 - 0.027 14.7 0.2 0.042 14.1 0.2 1.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal COMP PF11598.3 CBZ53681.1 - 0.035 14.1 0.2 0.061 13.4 0.1 1.3 1 0 0 1 1 1 0 Cartilage oligomeric matrix protein Peptidase_M3 PF01432.15 CBZ53682.1 - 2.1e-51 175.4 0.0 5e-42 144.5 0.0 2.8 2 1 0 2 2 2 2 Peptidase family M3 DUF2217 PF10265.4 CBZ53682.1 - 6 5.4 5.6 9.5 4.8 3.9 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) NPR3 PF03666.8 CBZ53683.1 - 0.051 12.1 2.1 0.074 11.5 1.5 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 ARF7EP_C PF14949.1 CBZ53683.1 - 0.45 10.9 3.9 1.2 9.5 2.7 1.7 1 0 0 1 1 1 0 ARF7 effector protein C-terminus SAPS PF04499.10 CBZ53683.1 - 0.8 8.2 5.3 1 7.9 3.7 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein CT47 PF15623.1 CBZ53683.1 - 1.3 8.6 17.5 2.6 7.7 12.2 1.4 1 0 0 1 1 1 0 Cancer/testis gene family 47 DDHD PF02862.12 CBZ53683.1 - 1.6 8.4 8.3 1.8 8.2 5.3 1.4 1 1 0 1 1 1 0 DDHD domain Dicty_REP PF05086.7 CBZ53683.1 - 3.4 5.3 7.4 4.4 4.9 5.1 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DHHW PF14286.1 CBZ53683.1 - 3.5 6.8 10.0 0.94 8.7 4.8 1.5 2 0 0 2 2 2 0 DHHW protein DUF1510 PF07423.6 CBZ53683.1 - 8.9 5.6 19.2 46 3.2 13.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) PDEase_I PF00233.14 CBZ53684.1 - 8.8e-53 179.4 0.0 1.6e-52 178.6 0.0 1.4 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase DUF846 PF05832.7 CBZ53684.1 - 0.87 9.2 8.9 0.096 12.3 0.7 2.4 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF846) Hexapep PF00132.19 CBZ53685.1 - 1.1e-07 31.0 0.3 0.07 12.6 0.5 3.6 1 1 2 3 3 3 3 Bacterial transferase hexapeptide (six repeats) NTP_transferase PF00483.18 CBZ53685.1 - 0.009 15.3 0.0 0.021 14.1 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyl transferase LSM PF01423.17 CBZ53686.1 - 8.3e-18 63.7 0.3 1.3e-17 63.1 0.2 1.3 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 CBZ53686.1 - 0.00092 19.0 0.0 0.0015 18.4 0.0 1.4 1 0 0 1 1 1 1 Ataxin 2 SM domain Flag1_repress PF03614.8 CBZ53686.1 - 0.1 12.1 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 Repressor of phase-1 flagellin Alpha_adaptinC2 PF02883.15 CBZ53688.1 - 7.4e-12 45.5 0.0 1.3e-11 44.8 0.0 1.3 1 0 0 1 1 1 1 Adaptin C-terminal domain Alpha_adaptin_C PF02296.11 CBZ53688.1 - 1.3e-06 28.2 0.0 2.3e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 Alpha adaptin AP2, C-terminal domain DUF3584 PF12128.3 CBZ53688.1 - 0.53 7.5 25.1 1.1 6.5 17.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Fib_alpha PF08702.5 CBZ53688.1 - 1.3 9.1 5.5 1.1 9.4 1.9 1.9 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family TMCO5 PF14992.1 CBZ53688.1 - 2.1 7.3 22.2 0.03 13.4 8.8 2.3 1 1 1 2 2 2 0 TMCO5 family IncA PF04156.9 CBZ53688.1 - 8.8 5.8 27.8 0.52 9.8 1.0 2.8 1 1 1 2 2 2 0 IncA protein DUF4455 PF14643.1 CBZ53689.1 - 3.4e-12 45.7 16.8 3.4e-12 45.7 11.7 6.6 6 2 0 7 7 7 4 Domain of unknown function (DUF4455) Prominin PF05478.6 CBZ53689.1 - 4.9 4.5 9.2 2 5.8 0.4 3.2 3 0 0 3 3 3 0 Prominin Dus PF01207.12 CBZ53690.1 - 1.3e-26 93.1 0.1 2.7e-11 42.8 0.0 3.5 4 0 0 4 4 4 3 Dihydrouridine synthase (Dus) SAG PF04092.8 CBZ53691.1 - 2.9e-43 147.2 21.0 9.5e-24 84.1 3.6 2.2 2 0 0 2 2 2 2 SRS domain SAG PF04092.8 CBZ53692.1 - 2.5e-41 140.9 21.1 1.8e-23 83.2 3.4 2.1 2 0 0 2 2 2 2 SRS domain Neocarzinostat PF00960.13 CBZ53692.1 - 0.68 9.8 8.4 0.048 13.5 1.1 2.4 2 1 0 2 2 2 0 Neocarzinostatin family SAG PF04092.8 CBZ53693.1 - 5.4e-41 139.8 19.1 7e-22 78.1 4.0 2.1 2 0 0 2 2 2 2 SRS domain SAG PF04092.8 CBZ53694.1 - 2.2e-40 137.8 13.7 9.1e-23 80.9 3.9 2.2 2 0 0 2 2 2 2 SRS domain SMK-1 PF04802.10 CBZ53695.1 - 4.2e-21 75.3 1.0 4.2e-21 75.3 0.7 1.7 2 0 0 2 2 2 1 Component of IIS longevity pathway SMK-1 Sec66 PF09802.4 CBZ53695.1 - 0.058 12.7 0.6 0.097 12.0 0.4 1.2 1 0 0 1 1 1 0 Preprotein translocase subunit Sec66 SRP-alpha_N PF04086.8 CBZ53695.1 - 1.3 8.3 5.8 4.1 6.6 4.0 1.8 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal CobU PF02283.11 CBZ53696.1 - 0.15 11.4 0.0 0.31 10.4 0.0 1.4 1 0 0 1 1 1 0 Cobinamide kinase / cobinamide phosphate guanyltransferase Pkinase PF00069.20 CBZ53697.1 - 9.6e-32 110.1 0.0 3.8e-19 68.8 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ53697.1 - 4e-13 49.0 0.0 4.4e-07 29.2 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.18 CBZ53697.1 - 0.007 16.1 0.1 0.014 15.1 0.1 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.1 CBZ53697.1 - 0.079 11.9 0.0 3.5 6.5 0.0 2.1 2 0 0 2 2 2 0 Kinase-like Presenilin PF01080.12 CBZ53699.1 - 2.2 7.0 4.1 3 6.5 2.9 1.1 1 0 0 1 1 1 0 Presenilin Asp PF00026.18 CBZ53700.1 - 6e-08 32.2 0.0 6.5e-08 32.1 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Sugar_tr PF00083.19 CBZ53701.1 - 1.2e-86 291.0 21.8 1.9e-86 290.4 15.1 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CBZ53701.1 - 2.6e-27 95.4 49.3 2.9e-25 88.7 16.5 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Amino_oxidase PF01593.19 CBZ53702.1 - 0.00013 21.1 0.1 0.0019 17.3 0.0 2.8 3 1 0 3 3 3 1 Flavin containing amine oxidoreductase Pkinase_Tyr PF07714.12 CBZ53703.1 - 1.2e-49 168.7 0.0 3e-30 105.1 0.0 3.1 3 0 0 3 3 3 3 Protein tyrosine kinase Pkinase PF00069.20 CBZ53703.1 - 2.6e-42 144.7 0.3 1.1e-25 90.3 1.1 3.4 2 1 0 2 2 2 2 Protein kinase domain Pex2_Pex12 PF04757.9 CBZ53704.1 - 0.0049 16.3 0.1 0.0085 15.5 0.1 1.3 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region Neur_chan_memb PF02932.11 CBZ53704.1 - 0.17 11.7 0.0 0.33 10.7 0.0 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region IncA PF04156.9 CBZ53704.1 - 0.35 10.4 5.0 0.054 13.0 0.7 1.7 2 0 0 2 2 2 0 IncA protein HemY_N PF07219.8 CBZ53704.1 - 0.41 10.2 3.4 0.85 9.1 0.5 2.4 2 0 0 2 2 2 0 HemY protein N-terminus MACPF PF01823.14 CBZ53706.1 - 2.6e-47 161.2 0.3 2.6e-47 161.2 0.2 1.7 2 0 0 2 2 2 1 MAC/Perforin domain LCAT PF02450.10 CBZ53707.1 - 3.2e-39 135.0 0.1 4.1e-34 118.2 0.1 2.1 2 0 0 2 2 2 2 Lecithin:cholesterol acyltransferase Abhydrolase_6 PF12697.2 CBZ53707.1 - 0.022 14.6 2.5 0.067 13.0 1.8 2.0 1 1 0 1 1 1 0 Alpha/beta hydrolase family DUF900 PF05990.7 CBZ53707.1 - 0.028 13.7 0.0 0.052 12.8 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) NAD_binding_11 PF14833.1 CBZ53708.1 - 1.9e-30 105.3 0.0 3.3e-30 104.6 0.0 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase NAD_binding_2 PF03446.10 CBZ53708.1 - 1.8e-29 102.6 0.0 1.9e-24 86.3 0.0 2.2 2 0 0 2 2 2 2 NAD binding domain of 6-phosphogluconate dehydrogenase CK_II_beta PF01214.13 CBZ53709.1 - 7.1e-66 221.2 0.0 9.2e-66 220.8 0.0 1.1 1 0 0 1 1 1 1 Casein kinase II regulatory subunit POTRA_2 PF08479.6 CBZ53710.1 - 0.28 10.8 0.0 1 9.0 0.0 1.9 2 0 0 2 2 2 0 POTRA domain, ShlB-type DUF1126 PF06565.7 CBZ53713.1 - 1.5e-31 107.5 0.3 1.5e-12 46.7 0.0 3.7 3 0 0 3 3 3 3 Repeat of unknown function (DUF1126) Mem_trans PF03547.13 CBZ53713.1 - 5.2 5.2 6.7 8.6 4.5 4.6 1.2 1 0 0 1 1 1 0 Membrane transport protein WD40 PF00400.27 CBZ53714.1 - 2.1e-29 100.3 6.6 6e-08 32.2 0.3 5.3 5 0 0 5 5 5 5 WD domain, G-beta repeat DUF3312 PF11768.3 CBZ53714.1 - 0.00096 17.4 0.0 0.002 16.4 0.0 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3312) IKI3 PF04762.7 CBZ53714.1 - 0.17 9.6 0.3 2.4 5.8 0.2 2.3 2 1 0 2 2 2 0 IKI3 family Telomere_Sde2_2 PF13297.1 CBZ53715.1 - 1.1e-20 72.6 0.0 1.9e-20 71.8 0.0 1.4 1 0 0 1 1 1 1 Telomere stability C-terminal AF-4 PF05110.8 CBZ53715.1 - 1.4e-05 23.2 28.1 1.9e-05 22.7 19.5 1.2 1 0 0 1 1 1 1 AF-4 proto-oncoprotein Telomere_Sde2 PF13019.1 CBZ53715.1 - 0.04 13.5 1.1 0.04 13.5 0.8 2.7 2 2 0 2 2 2 0 Telomere stability and silencing RAP1 PF07218.6 CBZ53715.1 - 0.16 10.0 16.4 0.23 9.5 11.4 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Macoilin PF09726.4 CBZ53715.1 - 0.79 7.9 19.4 1.1 7.4 13.4 1.3 1 0 0 1 1 1 0 Transmembrane protein Neur_chan_memb PF02932.11 CBZ53715.1 - 2.5 7.9 7.7 5 6.9 5.3 1.5 1 1 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF515 PF04415.7 CBZ53715.1 - 3.9 5.5 15.6 8.2 4.5 10.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF515) zf-DHHC PF01529.15 CBZ53716.1 - 3.4e-30 104.6 0.7 3.4e-30 104.6 0.5 1.6 2 0 0 2 2 2 1 DHHC palmitoyltransferase Ank_2 PF12796.2 CBZ53716.1 - 1.2e-20 73.6 3.9 4.6e-10 39.7 0.4 3.5 3 1 1 4 4 4 2 Ankyrin repeats (3 copies) Ank PF00023.25 CBZ53716.1 - 7.4e-18 63.3 6.9 3.9e-07 29.5 0.2 5.3 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.1 CBZ53716.1 - 3.1e-12 46.3 13.3 0.00014 21.9 0.2 5.9 3 2 3 6 6 6 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 CBZ53716.1 - 7.5e-12 45.4 6.2 1.7e-07 31.5 0.1 3.8 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 CBZ53716.1 - 2.7e-11 42.5 6.7 0.00097 19.1 0.1 5.4 5 0 0 5 5 5 3 Ankyrin repeat DUF605 PF04652.11 CBZ53716.1 - 1.9 7.7 37.9 0.51 9.6 21.8 2.2 2 0 0 2 2 2 0 Vta1 like Transket_pyr PF02779.19 CBZ53717.1 - 2e-46 157.6 0.0 3.1e-46 157.1 0.0 1.2 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 CBZ53717.1 - 1.1e-33 115.7 0.1 2.2e-33 114.8 0.1 1.5 1 0 0 1 1 1 1 Transketolase, C-terminal domain PP2C PF00481.16 CBZ53718.1 - 3e-41 141.5 0.0 2.6e-27 95.8 0.0 2.2 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.1 CBZ53718.1 - 4.3e-05 23.0 0.0 0.0089 15.4 0.0 3.0 2 1 0 2 2 2 2 Protein phosphatase 2C SpoIIE PF07228.7 CBZ53718.1 - 9e-05 22.2 0.0 0.00071 19.3 0.0 2.0 2 0 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) Radical_SAM PF04055.16 CBZ53719.1 - 3.9e-24 85.6 0.0 7.3e-24 84.8 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily Wyosine_form PF08608.7 CBZ53719.1 - 5.7e-17 61.5 0.0 1.3e-16 60.4 0.0 1.7 1 0 0 1 1 1 1 Wyosine base formation Flavodoxin_1 PF00258.20 CBZ53719.1 - 2.6e-06 27.4 0.0 3.2e-05 23.9 0.0 2.4 2 0 0 2 2 2 1 Flavodoxin Dpy-30 PF05186.8 CBZ53720.1 - 9.9e-13 47.3 0.1 2.1e-12 46.2 0.0 1.6 1 0 0 1 1 1 1 Dpy-30 motif Herpes_U47 PF05467.6 CBZ53721.1 - 0.091 10.5 0.7 0.13 10.0 0.5 1.1 1 0 0 1 1 1 0 Herpesvirus glycoprotein U47 Proteasome PF00227.21 CBZ53723.1 - 4.2e-18 65.3 0.1 1.8e-14 53.4 0.0 2.2 2 0 0 2 2 2 2 Proteasome subunit Cons_hypoth95 PF03602.10 CBZ53724.1 - 5.3e-32 110.6 0.0 1e-23 83.6 0.0 2.3 2 0 0 2 2 2 2 Conserved hypothetical protein 95 Methyltransf_26 PF13659.1 CBZ53724.1 - 3.1e-05 24.0 0.0 0.00027 20.9 0.0 2.5 2 1 0 2 2 2 1 Methyltransferase domain PrmA PF06325.8 CBZ53724.1 - 0.11 11.6 0.0 0.2 10.7 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.1 CBZ53724.1 - 0.23 11.0 0.0 0.43 10.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain MethyltransfD12 PF02086.10 CBZ53724.1 - 0.33 10.3 0.0 5.9 6.2 0.0 2.1 2 0 0 2 2 2 0 D12 class N6 adenine-specific DNA methyltransferase SRP-alpha_N PF04086.8 CBZ53724.1 - 0.99 8.7 4.5 2.4 7.4 3.1 1.5 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Pkinase PF00069.20 CBZ53725.1 - 4.3e-46 157.1 0.0 8.8e-46 156.1 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ53725.1 - 2.3e-22 79.3 0.1 4.4e-22 78.4 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CBZ53725.1 - 1.4e-08 34.8 0.1 0.00011 22.0 0.1 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.1 CBZ53725.1 - 6.1e-06 25.4 0.0 7e-05 21.9 0.0 2.3 2 1 0 2 2 2 1 Kinase-like YukC PF10140.4 CBZ53725.1 - 0.031 12.8 0.0 0.05 12.1 0.0 1.3 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC Pox_ser-thr_kin PF05445.6 CBZ53725.1 - 0.039 12.7 0.2 0.058 12.1 0.1 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Seadorna_VP7 PF07387.6 CBZ53725.1 - 0.15 10.8 0.1 0.22 10.3 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 Steroid_dh PF02544.11 CBZ53727.1 - 1.5e-17 63.7 0.1 1.2e-16 60.8 0.1 2.1 2 0 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase PEMT PF04191.8 CBZ53727.1 - 0.029 14.4 0.2 0.029 14.4 0.2 2.4 3 0 0 3 3 3 0 Phospholipid methyltransferase MIP-T3 PF10243.4 CBZ53729.1 - 0.034 12.6 87.4 0.041 12.3 60.6 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Ycf1 PF05758.7 CBZ53730.1 - 3 5.4 0.3 5 4.6 0.2 1.2 1 0 0 1 1 1 0 Ycf1 Kelch_1 PF01344.20 CBZ53731.1 - 1.8e-34 116.9 1.2 1.6e-12 46.7 0.0 5.2 5 0 0 5 5 5 4 Kelch motif Kelch_6 PF13964.1 CBZ53731.1 - 2.3e-20 71.8 0.1 5.3e-05 23.2 0.0 5.6 3 2 3 6 6 6 3 Kelch motif Kelch_4 PF13418.1 CBZ53731.1 - 1.5e-18 66.2 0.8 2.5e-05 23.9 0.0 4.3 4 0 0 4 4 4 3 Galactose oxidase, central domain Kelch_3 PF13415.1 CBZ53731.1 - 8.5e-17 60.8 3.9 1.9e-05 24.6 0.0 5.4 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_5 PF13854.1 CBZ53731.1 - 7.5e-09 35.3 2.6 0.24 11.3 0.0 4.7 4 0 0 4 4 4 4 Kelch motif Kelch_2 PF07646.10 CBZ53731.1 - 1.6e-08 33.9 1.1 0.16 11.7 0.0 4.4 4 0 0 4 4 4 3 Kelch motif Gar1 PF04410.9 CBZ53732.1 - 1.6e-29 102.3 0.1 1.6e-29 102.3 0.0 2.1 2 0 0 2 2 2 1 Gar1/Naf1 RNA binding region AAA_13 PF13166.1 CBZ53733.1 - 0.84 8.0 8.5 1.3 7.3 5.9 1.2 1 0 0 1 1 1 0 AAA domain Erp_C PF06780.6 CBZ53733.1 - 1.1 9.1 4.0 2.5 7.9 2.8 1.5 1 0 0 1 1 1 0 Erp protein C-terminus DUF4201 PF13870.1 CBZ53733.1 - 9.3 5.6 25.0 0.24 10.8 5.6 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) Bacillus_HBL PF05791.6 CBZ53734.1 - 7.5 5.8 7.1 14 4.9 0.2 2.2 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) MACPF PF01823.14 CBZ53735.1 - 7e-41 140.2 0.1 1.3e-40 139.3 0.1 1.5 1 0 0 1 1 1 1 MAC/Perforin domain SAG PF04092.8 CBZ53736.1 - 1.7e-31 109.1 0.1 1e-05 25.9 0.0 5.2 5 0 0 5 5 5 5 SRS domain DUF3273 PF11677.3 CBZ53737.1 - 2.2e-80 269.7 7.4 2.5e-80 269.5 5.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3273) Hint PF01079.15 CBZ53737.1 - 0.13 11.4 0.3 0.52 9.4 0.0 1.9 2 0 0 2 2 2 0 Hint module Amidase PF01425.16 CBZ53739.1 - 9.6e-05 21.4 0.6 0.061 12.1 0.0 2.2 2 0 0 2 2 2 2 Amidase CDC45 PF02724.9 CBZ53741.1 - 0.15 10.0 17.7 0.89 7.5 0.0 3.1 3 0 0 3 3 3 0 CDC45-like protein DUF2233 PF09992.4 CBZ53741.1 - 0.16 11.9 0.0 0.29 11.1 0.0 1.4 1 0 0 1 1 1 0 Predicted periplasmic protein (DUF2233) Nop14 PF04147.7 CBZ53741.1 - 5.7 4.7 16.6 11 3.8 11.5 1.3 1 0 0 1 1 1 0 Nop14-like family DnaJ PF00226.26 CBZ53742.1 - 9e-13 47.7 0.1 2.7e-12 46.2 0.1 1.9 1 1 0 1 1 1 1 DnaJ domain Shadoo PF14999.1 CBZ53742.1 - 2.3 8.0 9.9 4.5 7.1 0.4 3.3 3 0 0 3 3 3 0 Shadow of prion protein, neuroprotective GBP_C PF02841.9 CBZ53742.1 - 7.3 5.6 17.9 0.22 10.6 8.0 1.6 2 0 0 2 2 2 0 Guanylate-binding protein, C-terminal domain adh_short PF00106.20 CBZ53743.1 - 7e-21 74.8 0.1 1e-20 74.3 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase Thioesterase PF00975.15 CBZ53743.1 - 1.9e-16 61.0 0.0 1.7e-15 57.8 0.0 2.3 2 1 0 2 2 2 1 Thioesterase domain adh_short_C2 PF13561.1 CBZ53743.1 - 2e-10 40.8 0.1 2.9e-10 40.3 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Abhydrolase_6 PF12697.2 CBZ53743.1 - 1e-08 35.3 0.1 1.9e-08 34.4 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CBZ53743.1 - 2.4e-06 27.3 0.0 2.6e-05 24.0 0.0 2.2 2 0 0 2 2 2 1 Alpha/beta hydrolase family NAD_binding_10 PF13460.1 CBZ53743.1 - 6.3e-06 26.3 0.1 1.7e-05 24.9 0.1 1.7 1 0 0 1 1 1 1 NADH(P)-binding KR PF08659.5 CBZ53743.1 - 8.5e-05 22.2 0.2 0.00019 21.1 0.0 1.6 2 0 0 2 2 2 1 KR domain DUF1776 PF08643.5 CBZ53743.1 - 0.0013 17.9 0.0 0.0056 15.8 0.0 1.9 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) Pyr_redox PF00070.22 CBZ53743.1 - 0.016 15.5 0.0 0.11 12.9 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Glyco_tran_WecB PF03808.8 CBZ53743.1 - 0.055 12.8 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase WecB/TagA/CpsF family Epimerase PF01370.16 CBZ53743.1 - 0.099 12.0 0.1 0.36 10.2 0.1 1.9 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family NmrA PF05368.8 CBZ53743.1 - 0.13 11.4 0.1 0.19 10.9 0.1 1.2 1 0 0 1 1 1 0 NmrA-like family zf-B_box PF00643.19 CBZ53744.1 - 3.2e-11 42.9 13.0 2.1e-06 27.5 2.4 2.4 2 0 0 2 2 2 2 B-box zinc finger Daxx PF03344.10 CBZ53744.1 - 0.00012 20.7 47.5 0.00012 20.7 32.9 2.2 2 0 0 2 2 2 1 Daxx Family Fzo_mitofusin PF04799.8 CBZ53744.1 - 2.2 7.6 4.3 4.1 6.7 0.3 2.3 1 1 1 2 2 2 0 fzo-like conserved region Ycf1 PF05758.7 CBZ53744.1 - 4 5.0 21.6 7.7 4.0 15.0 1.4 1 0 0 1 1 1 0 Ycf1 Peptidase_M14 PF00246.19 CBZ53745.1 - 1e-33 117.1 0.0 1.3e-30 106.9 0.0 2.2 1 1 1 2 2 2 2 Zinc carboxypeptidase tRNA_U5-meth_tr PF05958.6 CBZ53746.1 - 1.1e-18 67.0 0.0 4.9e-18 64.9 0.0 1.8 1 1 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_18 PF12847.2 CBZ53746.1 - 1.7e-07 31.7 0.0 3.8e-07 30.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CBZ53746.1 - 5.5e-07 29.2 0.0 1.1e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 CBZ53746.1 - 1.1e-05 25.4 0.0 2.9e-05 24.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.5 CBZ53746.1 - 5.5e-05 22.7 0.0 0.00011 21.7 0.0 1.5 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase PrmA PF06325.8 CBZ53746.1 - 0.00096 18.3 0.0 0.0015 17.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.7 CBZ53746.1 - 0.0016 18.8 0.0 0.0035 17.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 CBZ53746.1 - 0.0019 17.5 0.0 0.0035 16.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Met_10 PF02475.11 CBZ53746.1 - 0.005 16.4 0.0 0.0084 15.7 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_23 PF13489.1 CBZ53746.1 - 0.007 16.0 0.0 0.023 14.4 0.0 1.9 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 CBZ53746.1 - 0.018 15.3 0.0 0.038 14.3 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.7 CBZ53746.1 - 0.024 15.1 0.0 0.053 13.9 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain TRM PF02005.11 CBZ53746.1 - 0.25 10.2 0.0 0.42 9.4 0.0 1.3 1 0 0 1 1 1 0 N2,N2-dimethylguanosine tRNA methyltransferase RAP PF08373.5 CBZ53747.1 - 0.0014 18.4 0.0 0.0031 17.2 0.0 1.5 1 0 0 1 1 1 1 RAP domain FAST_1 PF06743.10 CBZ53747.1 - 0.016 14.8 2.0 6.6 6.5 0.0 3.9 3 1 1 4 4 4 0 FAST kinase-like protein, subdomain 1 BPL_LplA_LipB PF03099.14 CBZ53748.1 - 3.2e-19 69.1 0.0 1.9e-18 66.6 0.0 2.1 2 0 0 2 2 2 1 Biotin/lipoate A/B protein ligase family Lip_prot_lig_C PF10437.4 CBZ53748.1 - 2.6e-17 62.2 0.0 6.1e-17 61.0 0.0 1.7 2 0 0 2 2 2 1 Bacterial lipoate protein ligase C-terminus LRR_9 PF14580.1 CBZ53749.1 - 4.2e-11 42.7 0.0 6.4e-11 42.1 0.0 1.3 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.2 CBZ53749.1 - 3.5e-10 39.2 1.8 4.7e-05 22.9 0.0 3.0 1 1 3 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CBZ53749.1 - 1.7e-05 24.4 2.8 0.0034 17.0 0.1 2.5 1 1 2 3 3 3 3 Leucine rich repeat LRR_6 PF13516.1 CBZ53749.1 - 0.16 12.0 1.6 42 4.6 0.0 3.7 4 0 0 4 4 4 0 Leucine Rich repeat DUF676 PF05057.9 CBZ53750.1 - 3.3e-30 105.0 0.0 1.6e-26 92.9 0.0 2.2 2 0 0 2 2 2 2 Putative serine esterase (DUF676) Abhydrolase_5 PF12695.2 CBZ53750.1 - 0.055 13.2 0.0 0.11 12.2 0.0 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase family EB1 PF03271.12 CBZ53751.1 - 0.0027 17.7 0.7 0.0084 16.1 0.5 1.9 1 1 0 1 1 1 1 EB1-like C-terminal motif YlqD PF11068.3 CBZ53751.1 - 0.12 12.3 0.5 0.16 12.0 0.3 1.2 1 0 0 1 1 1 0 YlqD protein NEMO PF11577.3 CBZ53751.1 - 1.1 9.0 4.7 4.7 7.0 0.5 2.4 2 0 0 2 2 2 0 NF-kappa-B essential modulator NEMO Filamin PF00630.14 CBZ53752.1 - 3.8e-14 53.0 0.5 3.6e-10 40.3 0.0 3.2 3 0 0 3 3 3 2 Filamin/ABP280 repeat Gp5_C PF06715.7 CBZ53752.1 - 6.9e-08 31.8 0.0 1.1e+02 3.0 0.0 8.5 5 2 1 9 9 9 0 Gp5 C-terminal repeat (3 copies) RBM39linker PF15519.1 CBZ53753.1 - 0.0068 16.6 0.4 0.17 12.2 0.2 3.0 3 0 0 3 3 3 1 linker between RRM2 and RRM3 domains in RBM39 protein Pol_alpha_B_N PF08418.5 CBZ53753.1 - 0.075 12.5 2.2 0.095 12.2 1.6 1.2 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal Thioredoxin PF00085.15 CBZ53754.1 - 4.7e-20 71.2 0.0 6.5e-11 41.8 0.0 3.7 5 0 0 5 5 5 2 Thioredoxin Thioredoxin_6 PF13848.1 CBZ53754.1 - 1.8e-17 63.7 0.0 4.6e-08 33.0 0.0 3.3 4 0 0 4 4 4 2 Thioredoxin-like domain Thioredoxin_2 PF13098.1 CBZ53754.1 - 1.5e-05 25.1 0.0 0.054 13.6 0.0 2.9 2 1 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_8 PF13905.1 CBZ53754.1 - 5.7e-05 23.1 0.0 0.19 11.8 0.0 2.9 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_7 PF13899.1 CBZ53754.1 - 0.00013 21.8 0.0 0.49 10.4 0.0 2.9 3 0 0 3 3 3 2 Thioredoxin-like AhpC-TSA PF00578.16 CBZ53754.1 - 0.035 13.7 0.1 0.13 11.8 0.0 1.9 2 0 0 2 2 2 0 AhpC/TSA family Calsequestrin PF01216.12 CBZ53754.1 - 0.21 10.3 0.0 0.4 9.4 0.0 1.3 1 0 0 1 1 1 0 Calsequestrin EF-hand_6 PF13405.1 CBZ53755.1 - 3.4e-08 32.7 0.0 0.00051 19.6 0.0 2.6 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.1 CBZ53755.1 - 2.2e-07 30.9 0.1 0.015 15.4 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 CBZ53755.1 - 7.4e-05 21.7 0.0 0.017 14.3 0.0 2.7 2 0 0 2 2 2 2 EF hand EF-hand_9 PF14658.1 CBZ53755.1 - 0.0015 18.3 0.0 0.21 11.5 0.0 2.3 2 0 0 2 2 2 1 EF-hand domain Sda PF08970.5 CBZ53755.1 - 0.029 13.8 0.6 0.32 10.5 0.0 2.3 2 0 0 2 2 2 0 Sporulation inhibitor A SAG PF04092.8 CBZ53756.1 - 1.5e-34 119.0 9.4 1.3e-18 67.6 1.1 2.1 2 0 0 2 2 2 2 SRS domain Resistin PF06954.6 CBZ53756.1 - 0.089 13.0 0.5 0.089 13.0 0.4 2.4 3 0 0 3 3 3 0 Resistin PHD PF00628.24 CBZ53757.1 - 0.0034 17.0 3.9 0.0034 17.0 2.7 3.2 3 0 0 3 3 3 1 PHD-finger tRNA-synt_2b PF00587.20 CBZ53758.1 - 9.1e-25 87.2 0.0 1.4e-24 86.6 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HTH_39 PF14090.1 CBZ53758.1 - 0.076 12.4 0.2 0.29 10.6 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain Seryl_tRNA_N PF02403.17 CBZ53758.1 - 2.1 8.4 5.9 9 6.3 4.1 2.0 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain P5CR_dimer PF14748.1 CBZ53759.1 - 4.1e-29 100.7 0.3 7.4e-29 99.9 0.2 1.4 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.12 CBZ53759.1 - 3.1e-09 37.1 0.1 5.8e-09 36.2 0.1 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.10 CBZ53759.1 - 0.014 15.2 0.0 0.028 14.2 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_Gly3P_dh_N PF01210.18 CBZ53759.1 - 0.11 12.1 0.1 0.55 9.9 0.0 2.0 1 1 2 3 3 3 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus GBP PF02263.14 CBZ53761.1 - 0.62 9.0 3.1 1.1 8.3 2.1 1.3 1 0 0 1 1 1 0 Guanylate-binding protein, N-terminal domain Metal_resist PF13801.1 CBZ53762.1 - 0.23 11.4 0.1 0.31 11.0 0.0 1.1 1 0 0 1 1 1 0 Heavy-metal resistance DUF2617 PF10936.3 CBZ53763.1 - 0.066 12.7 0.4 0.11 12.0 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF2617 GBP PF02263.14 CBZ53763.1 - 0.13 11.2 3.2 0.17 10.8 2.2 1.1 1 0 0 1 1 1 0 Guanylate-binding protein, N-terminal domain YTV PF07639.6 CBZ53763.1 - 0.89 9.3 20.7 1.8 8.3 0.1 4.5 3 1 1 4 4 4 0 YTV Abhydrolase_5 PF12695.2 CBZ53765.1 - 5.5e-19 68.3 0.0 9.6e-19 67.5 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CBZ53765.1 - 1.3e-12 48.1 0.6 3.6e-12 46.6 0.4 1.8 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CBZ53765.1 - 0.00012 21.7 0.0 0.00031 20.3 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 CBZ53765.1 - 0.00063 19.5 0.0 0.0012 18.6 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase Peptidase_S15 PF02129.13 CBZ53765.1 - 0.011 15.1 0.0 0.02 14.3 0.0 1.3 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) NPL4 PF05021.10 CBZ53766.1 - 7.4e-66 222.3 0.0 1.1e-65 221.8 0.0 1.2 1 0 0 1 1 1 1 NPL4 family UN_NPL4 PF11543.3 CBZ53766.1 - 3e-11 43.4 0.0 1.5e-10 41.2 0.0 2.1 2 0 0 2 2 2 1 Nuclear pore localisation protein NPL4 zf-NPL4 PF05020.10 CBZ53766.1 - 3.4e-06 26.7 0.1 1.1e-05 25.1 0.0 1.9 2 0 0 2 2 2 1 NPL4 family, putative zinc binding region TPR_20 PF14561.1 CBZ53767.1 - 0.0095 16.0 1.3 0.039 14.0 0.9 2.1 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.1 CBZ53767.1 - 0.0096 16.4 0.1 0.0096 16.4 0.1 4.0 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.1 CBZ53767.1 - 0.013 15.3 1.8 3.8 7.5 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.1 CBZ53767.1 - 0.021 14.4 3.9 0.14 11.8 0.2 3.2 3 0 0 3 3 3 0 TPR repeat TPR_2 PF07719.12 CBZ53767.1 - 0.024 14.5 3.9 0.12 12.3 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.23 CBZ53767.1 - 0.032 13.8 0.0 0.082 12.5 0.0 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_16 PF13432.1 CBZ53767.1 - 0.035 14.7 0.7 0.035 14.7 0.5 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat Fork_head PF00250.13 CBZ53767.1 - 0.15 12.1 0.0 0.42 10.6 0.0 1.7 1 0 0 1 1 1 0 Fork head domain TPR_6 PF13174.1 CBZ53767.1 - 0.19 12.2 1.2 0.48 11.0 0.1 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat Porphobil_deam PF01379.15 CBZ53768.1 - 1.1e-50 171.4 0.0 4.2e-26 91.2 0.0 4.2 4 0 0 4 4 4 4 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.10 CBZ53768.1 - 1.2e-13 50.9 0.1 4.2e-13 49.1 0.0 1.9 1 1 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain Utp11 PF03998.8 CBZ53769.1 - 1.4e-20 74.2 25.5 2.1e-15 57.1 14.8 3.2 1 1 1 2 2 2 2 Utp11 protein tRNA_int_endo PF01974.12 CBZ53769.1 - 0.048 13.4 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 tRNA intron endonuclease, catalytic C-terminal domain PUB PF09409.5 CBZ53770.1 - 0.0044 16.7 0.0 0.0077 15.9 0.0 1.4 1 0 0 1 1 1 1 PUB domain Rhodanese PF00581.15 CBZ53770.1 - 0.024 15.0 0.0 3.6 7.9 0.0 2.8 2 0 0 2 2 2 0 Rhodanese-like domain Mur_ligase_M PF08245.7 CBZ53773.1 - 4.9e-12 46.2 0.0 9.3e-12 45.3 0.0 1.5 1 0 0 1 1 1 1 Mur ligase middle domain Mur_ligase_C PF02875.16 CBZ53773.1 - 0.014 15.4 0.0 3.1 7.9 0.0 3.1 3 0 0 3 3 3 0 Mur ligase family, glutamate ligase domain CbiA PF01656.18 CBZ53773.1 - 0.029 13.7 0.0 0.066 12.6 0.0 1.6 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain SRP54 PF00448.17 CBZ53773.1 - 0.075 12.4 0.2 0.16 11.3 0.1 1.5 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain DUF4471 PF14740.1 CBZ53774.1 - 5.8e-35 120.9 2.7 1.6e-16 60.3 0.8 3.4 2 1 1 3 3 3 3 Domain of unknown function (DUF4471) DUF4470 PF14737.1 CBZ53774.1 - 1.4e-15 56.7 0.0 2.7e-15 55.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) SHS2_Rpb7-N PF03876.12 CBZ53775.1 - 3.2e-13 49.6 0.0 5.3e-13 48.8 0.0 1.4 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.18 CBZ53775.1 - 6.9e-07 29.2 0.0 1.1e-06 28.6 0.0 1.3 1 0 0 1 1 1 1 S1 RNA binding domain DRY_EERY PF09750.4 CBZ53776.1 - 2e-12 47.3 0.3 2e-12 47.3 0.2 2.8 2 0 0 2 2 2 1 Alternative splicing regulator Surp PF01805.15 CBZ53776.1 - 6.9e-07 28.8 0.0 0.00045 19.7 0.0 2.4 2 0 0 2 2 2 2 Surp module UPF0113 PF03657.8 CBZ53777.1 - 7.4e-11 41.9 0.0 9.2e-11 41.6 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0113) AKAP7_NLS PF10469.4 CBZ53780.1 - 1.4e-52 178.4 0.0 7.9e-52 176.0 0.0 2.0 2 0 0 2 2 2 1 AKAP7 2'5' RNA ligase-like domain KH_1 PF00013.24 CBZ53780.1 - 8.4e-10 38.1 0.0 1.9e-09 37.0 0.0 1.6 1 0 0 1 1 1 1 KH domain KH_3 PF13014.1 CBZ53780.1 - 2.3e-07 30.2 0.0 4.5e-07 29.3 0.0 1.5 1 0 0 1 1 1 1 KH domain Glyco_hydro_77 PF02446.12 CBZ53783.1 - 2.3e-123 412.4 0.5 2.9e-123 412.0 0.3 1.1 1 0 0 1 1 1 1 4-alpha-glucanotransferase Bin3 PF06859.7 CBZ53785.1 - 1.1e-25 89.6 0.0 2.2e-25 88.7 0.0 1.4 1 0 0 1 1 1 1 Bicoid-interacting protein 3 (Bin3) Methyltransf_18 PF12847.2 CBZ53785.1 - 4.4e-10 40.1 0.0 1.8e-05 25.2 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.1 CBZ53785.1 - 5.4e-10 39.2 0.0 0.0007 19.3 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_31 PF13847.1 CBZ53785.1 - 1.1e-07 31.6 0.0 0.00024 20.6 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.7 CBZ53785.1 - 7.6e-06 26.3 0.0 0.1 13.1 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.7 CBZ53785.1 - 1.1e-05 25.8 0.4 0.14 12.6 0.0 3.1 3 0 0 3 3 3 2 Methyltransferase domain Methyltransf_25 PF13649.1 CBZ53785.1 - 0.0011 19.2 0.1 0.35 11.2 0.0 2.7 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.8 CBZ53785.1 - 0.0084 15.2 0.0 0.017 14.2 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.9 CBZ53785.1 - 0.066 12.5 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain FmrO PF07091.6 CBZ53785.1 - 0.075 12.0 0.0 0.34 9.8 0.0 1.9 2 0 0 2 2 2 0 Ribosomal RNA methyltransferase (FmrO) ARGLU PF15346.1 CBZ53786.1 - 2.7e-34 118.0 43.9 2.7e-34 118.0 30.5 2.6 2 1 0 2 2 2 1 Arginine and glutamate-rich 1 CTP_transf_1 PF01148.15 CBZ53787.1 - 1.3e-05 25.0 11.0 8.3e-05 22.3 7.6 2.2 1 1 0 1 1 1 1 Cytidylyltransferase family PHO4 PF01384.15 CBZ53787.1 - 0.16 10.5 2.7 0.2 10.2 1.9 1.2 1 0 0 1 1 1 0 Phosphate transporter family Exo_endo_phos PF03372.18 CBZ53789.1 - 3.7e-15 56.5 1.3 3.4e-13 50.1 0.1 2.6 2 0 0 2 2 2 2 Endonuclease/Exonuclease/phosphatase family NUC153 PF08159.7 CBZ53791.1 - 1.7e-12 46.7 11.2 2.7e-11 42.8 1.8 3.0 2 0 0 2 2 2 2 NUC153 domain Nop14 PF04147.7 CBZ53791.1 - 0.0011 17.0 31.5 0.0011 17.0 21.8 4.1 3 1 2 5 5 5 2 Nop14-like family RRM_5 PF13893.1 CBZ53791.1 - 0.03 14.1 0.0 0.075 12.9 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Spc24 PF08286.6 CBZ53792.1 - 1.9 8.2 9.6 0.84 9.3 0.9 2.7 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 OTU PF02338.14 CBZ53793.1 - 1.3e-09 38.7 0.0 2.5e-09 37.7 0.0 1.5 1 0 0 1 1 1 1 OTU-like cysteine protease LRV PF01816.12 CBZ53793.1 - 1.2 9.4 4.6 5.3 7.4 0.1 3.8 3 0 0 3 3 3 0 Leucine rich repeat variant Sec1 PF00995.18 CBZ53794.1 - 5.7e-141 470.9 0.0 6.4e-141 470.7 0.0 1.0 1 0 0 1 1 1 1 Sec1 family SAG PF04092.8 CBZ53795.1 - 4.5e-13 49.6 2.9 6.7e-13 49.1 2.0 1.3 1 0 0 1 1 1 1 SRS domain DEC-1_C PF04626.8 CBZ53795.1 - 0.039 14.1 0.0 0.055 13.6 0.0 1.2 1 0 0 1 1 1 0 Dec-1 protein, C terminal region s48_45 PF07422.8 CBZ53795.1 - 0.042 13.9 0.0 0.075 13.1 0.0 1.4 1 0 0 1 1 1 0 Sexual stage antigen s48/45 domain SAG PF04092.8 CBZ53796.1 - 2.5e-07 31.0 0.0 3.2e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 SRS domain s48_45 PF07422.8 CBZ53796.1 - 0.0049 16.9 0.0 0.0067 16.5 0.0 1.2 1 0 0 1 1 1 1 Sexual stage antigen s48/45 domain AP2 PF00847.15 CBZ53797.1 - 4.6e-09 36.2 0.4 9e-09 35.3 0.3 1.5 1 0 0 1 1 1 1 AP2 domain His_Phos_1 PF00300.17 CBZ53799.1 - 3.3e-05 24.0 9.4 0.00022 21.3 5.0 2.7 1 1 1 2 2 2 1 Histidine phosphatase superfamily (branch 1) DUF1253 PF06862.7 CBZ53801.1 - 4.2e-120 401.1 0.0 2.3e-77 260.3 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF1253) Arginase PF00491.16 CBZ53801.1 - 0.052 12.8 0.0 0.095 11.9 0.0 1.3 1 0 0 1 1 1 0 Arginase family Myosin_tail_1 PF01576.14 CBZ53803.1 - 0.012 13.3 21.5 0.021 12.5 14.4 1.6 1 1 0 1 1 1 0 Myosin tail Filament PF00038.16 CBZ53803.1 - 0.026 14.0 18.2 0.011 15.2 3.2 2.2 1 1 0 2 2 2 0 Intermediate filament protein DUF972 PF06156.8 CBZ53803.1 - 0.031 14.6 11.2 0.15 12.4 0.6 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF972) CENP-Q PF13094.1 CBZ53803.1 - 0.082 12.9 25.0 0.12 12.4 5.7 2.6 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Bap31 PF05529.7 CBZ53803.1 - 0.18 11.2 10.7 0.04 13.3 0.8 2.3 2 0 0 2 2 2 0 B-cell receptor-associated protein 31-like DUF2265 PF10023.4 CBZ53803.1 - 0.47 9.5 7.1 0.7 8.9 4.9 1.1 1 0 0 1 1 1 0 Predicted aminopeptidase (DUF2265) DUF1664 PF07889.7 CBZ53803.1 - 0.95 9.2 3.2 17 5.2 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Tropomyosin PF00261.15 CBZ53803.1 - 1.5 7.8 24.7 1.8 7.5 5.8 2.7 1 1 1 2 2 2 0 Tropomyosin AAA_13 PF13166.1 CBZ53803.1 - 1.7 7.0 6.0 4.1 5.7 3.6 1.6 1 1 0 1 1 1 0 AAA domain DivIC PF04977.10 CBZ53803.1 - 4.1 6.9 8.9 1.8 8.1 0.4 2.7 1 1 1 2 2 2 0 Septum formation initiator DUF812 PF05667.6 CBZ53803.1 - 6.4 5.1 15.5 6.8 5.0 1.9 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF812) Tho2 PF11262.3 CBZ53804.1 - 7.7e-61 205.7 0.0 5.3e-47 160.2 0.0 2.4 2 0 0 2 2 2 2 Transcription factor/nuclear export subunit protein 2 Atg14 PF10186.4 CBZ53804.1 - 0.4 9.5 5.8 0.91 8.3 4.0 1.5 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Med5 PF08689.5 CBZ53804.1 - 6.8 4.2 0.0 11 3.5 0.0 1.2 1 0 0 1 1 1 0 Mediator complex subunit Med5 Kinase-like PF14531.1 CBZ53805.1 - 1.8e-25 89.5 0.0 2.2e-22 79.3 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Pkinase PF00069.20 CBZ53805.1 - 2.6e-17 62.8 0.0 4.7e-16 58.7 0.0 2.3 2 0 0 2 2 2 1 Protein kinase domain Kdo PF06293.9 CBZ53805.1 - 0.0079 15.2 0.0 0.014 14.4 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.12 CBZ53805.1 - 0.1 11.6 0.0 0.2 10.6 0.0 1.4 2 0 0 2 2 2 0 Protein tyrosine kinase Acyltransferase PF01553.16 CBZ53806.1 - 1.5e-10 40.5 0.0 2.7e-10 39.8 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase AAA PF00004.24 CBZ53807.1 - 4.9e-10 39.7 0.0 1.3e-09 38.2 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 CBZ53807.1 - 0.00039 21.2 0.1 0.0024 18.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 CBZ53807.1 - 0.00047 20.3 0.0 0.0013 18.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 CBZ53807.1 - 0.00051 20.0 11.0 0.00099 19.1 0.0 4.3 3 1 1 4 4 4 1 AAA ATPase domain NACHT PF05729.7 CBZ53807.1 - 0.00068 19.3 0.1 0.024 14.3 0.1 2.6 1 1 0 1 1 1 1 NACHT domain Rad17 PF03215.10 CBZ53807.1 - 0.0018 17.0 0.0 1.6 7.3 0.0 2.3 2 0 0 2 2 2 2 Rad17 cell cycle checkpoint protein AAA_19 PF13245.1 CBZ53807.1 - 0.0021 17.7 0.4 0.015 15.0 0.0 2.6 3 0 0 3 3 2 1 Part of AAA domain RuvB_N PF05496.7 CBZ53807.1 - 0.0033 16.4 0.0 0.0079 15.2 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_25 PF13481.1 CBZ53807.1 - 0.0066 15.8 0.0 1.4 8.2 0.0 2.9 2 0 0 2 2 2 1 AAA domain DNA_pol3_delta PF06144.8 CBZ53807.1 - 0.0068 15.9 0.0 0.011 15.2 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_5 PF07728.9 CBZ53807.1 - 0.023 14.4 0.0 0.057 13.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) NTPase_1 PF03266.10 CBZ53807.1 - 0.1 12.3 0.0 0.22 11.2 0.0 1.5 1 0 0 1 1 1 0 NTPase AAA_14 PF13173.1 CBZ53807.1 - 0.15 11.9 0.0 0.6 10.0 0.0 2.1 1 1 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 CBZ53807.1 - 0.32 10.6 0.0 0.65 9.6 0.0 1.4 1 0 0 1 1 1 0 Archaeal ATPase RRM_1 PF00076.17 CBZ53809.1 - 0.028 14.0 0.0 0.046 13.3 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TFIIF_alpha PF05793.7 CBZ53809.1 - 8.3 4.6 18.1 13 4.0 12.5 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Guanylate_cyc PF00211.15 CBZ53811.1 - 3.7e-19 68.7 0.0 2.5e-09 36.7 0.0 2.3 2 0 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain Glyco_hydro_17 PF00332.13 CBZ53812.1 - 5.2e-37 127.5 0.0 6.7e-37 127.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 17 PARP PF00644.15 CBZ53813.1 - 1.1e-35 122.9 0.0 1.1e-35 122.9 0.0 1.9 2 0 0 2 2 2 1 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.9 CBZ53813.1 - 1.3e-29 102.5 0.1 2.9e-29 101.4 0.1 1.6 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain WGR PF05406.10 CBZ53813.1 - 4e-10 39.5 0.7 1.1e-09 38.0 0.5 1.8 1 0 0 1 1 1 1 WGR domain zf-PARP PF00645.13 CBZ53813.1 - 1.6e-07 31.4 0.0 3.9e-07 30.2 0.0 1.7 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region PADR1 PF08063.7 CBZ53813.1 - 4.1e-07 29.2 0.1 1.2e-06 27.7 0.1 1.8 1 0 0 1 1 1 1 PADR1 (NUC008) domain BRCT PF00533.21 CBZ53813.1 - 9.2e-07 28.9 0.0 5.1e-06 26.5 0.0 2.2 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 CBZ53813.1 - 0.055 13.3 0.0 0.13 12.1 0.0 1.7 1 0 0 1 1 1 0 twin BRCT domain LSM PF01423.17 CBZ53814.1 - 5.5e-19 67.4 0.5 6.7e-19 67.2 0.3 1.1 1 0 0 1 1 1 1 LSM domain DUF2453 PF10507.4 CBZ53817.1 - 3.2e-29 100.9 2.8 7.7e-29 99.7 2.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2453) GAF PF01590.21 CBZ53817.1 - 3.8e-12 46.5 0.0 8.1e-12 45.5 0.0 1.5 1 0 0 1 1 1 1 GAF domain GAF_3 PF13492.1 CBZ53817.1 - 2.1e-11 44.0 0.0 1.5e-10 41.3 0.0 2.2 1 1 0 1 1 1 1 GAF domain GAF_2 PF13185.1 CBZ53817.1 - 2.4e-07 31.3 0.0 5.9e-07 30.0 0.0 1.7 1 0 0 1 1 1 1 GAF domain DUF2040 PF09745.4 CBZ53817.1 - 0.031 14.0 12.2 0.073 12.8 8.5 1.5 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 55 (DUF2040) Borrelia_P83 PF05262.6 CBZ53817.1 - 0.11 10.7 6.5 0.15 10.2 4.5 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein Hid1 PF12722.2 CBZ53817.1 - 0.12 9.9 3.7 0.16 9.5 2.6 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Spore_coat_CotO PF14153.1 CBZ53817.1 - 0.79 9.1 11.4 1.3 8.4 7.9 1.3 1 0 0 1 1 1 0 Spore coat protein CotO DUF1510 PF07423.6 CBZ53817.1 - 1 8.6 13.0 2.2 7.6 9.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) RR_TM4-6 PF06459.7 CBZ53817.1 - 1.4 8.7 10.9 2.3 8.0 7.6 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Ycf1 PF05758.7 CBZ53817.1 - 1.7 6.2 4.1 2.3 5.8 2.8 1.1 1 0 0 1 1 1 0 Ycf1 Zip PF02535.17 CBZ53817.1 - 3 6.7 5.5 0.45 9.4 0.4 2.0 2 0 0 2 2 2 0 ZIP Zinc transporter NARP1 PF12569.3 CBZ53817.1 - 4.5 5.9 13.2 6.6 5.3 9.2 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DUF1168 PF06658.7 CBZ53818.1 - 1.2e-24 86.4 16.1 1.2e-24 86.4 11.2 2.6 1 1 1 2 2 2 1 Protein of unknown function (DUF1168) RNA_pol_Rpb6 PF01192.17 CBZ53819.1 - 8.4e-20 70.2 0.2 1.4e-19 69.6 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb6 PWI PF01480.12 CBZ53820.1 - 5e-15 55.3 0.6 1.3e-14 54.0 0.4 1.7 1 0 0 1 1 1 1 PWI domain RRM_1 PF00076.17 CBZ53820.1 - 1.2e-06 27.9 0.0 2.7e-06 26.9 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBZ53820.1 - 0.001 18.9 0.0 0.0022 17.9 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Asn_synthase PF00733.16 CBZ53821.1 - 6.6e-22 78.2 7.1 5.3e-15 55.5 0.0 3.1 2 1 0 2 2 2 2 Asparagine synthase GATase_7 PF13537.1 CBZ53821.1 - 0.21 11.3 0.0 0.43 10.3 0.0 1.4 1 0 0 1 1 1 0 Glutamine amidotransferase domain HHH_5 PF14520.1 CBZ53822.1 - 0.00084 19.4 0.0 0.036 14.2 0.0 2.6 2 0 0 2 2 2 1 Helix-hairpin-helix domain Cwf_Cwc_15 PF04889.7 CBZ53823.1 - 4.6e-58 196.8 22.7 2.1e-55 188.1 15.7 2.0 1 1 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein APG6 PF04111.7 CBZ53823.1 - 0.1 11.6 7.6 0.14 11.2 5.3 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF2890 PF11081.3 CBZ53823.1 - 0.1 12.6 18.2 0.076 13.0 11.6 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2890) Nop14 PF04147.7 CBZ53823.1 - 0.35 8.7 16.6 0.42 8.4 11.5 1.1 1 0 0 1 1 1 0 Nop14-like family Spt5_N PF11942.3 CBZ53823.1 - 0.88 10.2 16.1 0.36 11.4 8.6 2.0 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal CDC27 PF09507.5 CBZ53823.1 - 1.5 7.9 17.5 1.8 7.6 12.1 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 AAA_23 PF13476.1 CBZ53823.1 - 3.3 7.9 6.9 1.8 8.8 3.6 1.6 2 0 0 2 2 2 0 AAA domain Nipped-B_C PF12830.2 CBZ53824.1 - 0.0051 16.4 0.5 0.078 12.6 0.0 2.4 2 0 0 2 2 2 1 Sister chromatid cohesion C-terminus Wbp11 PF09429.5 CBZ53825.1 - 6.4e-20 70.9 13.5 1.8e-19 69.5 9.3 1.8 1 0 0 1 1 1 1 WW domain binding protein 11 Dynamin_N PF00350.18 CBZ53827.1 - 1.3e-14 54.4 0.0 3.1e-14 53.1 0.0 1.6 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.18 CBZ53827.1 - 0.019 14.9 0.0 0.044 13.7 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase Miro PF08477.8 CBZ53827.1 - 0.048 14.1 0.0 0.1 13.0 0.0 1.6 1 0 0 1 1 1 0 Miro-like protein HTH_44 PF14641.1 CBZ53830.1 - 0.04 13.9 0.1 0.11 12.4 0.1 1.7 1 0 0 1 1 1 0 Helix-turn-helix DNA-binding domain of SPT6 BBS2_C PF14782.1 CBZ53830.1 - 6.5 5.1 10.6 6.2 5.2 1.3 2.1 1 1 1 2 2 2 0 Ciliary BBSome complex subunit 2, C-terminal DeoC PF01791.4 CBZ53831.1 - 1.1e-26 93.5 1.0 1.3e-26 93.3 0.7 1.1 1 0 0 1 1 1 1 DeoC/LacD family aldolase RRM_1 PF00076.17 CBZ53832.1 - 1.4e-18 66.2 0.0 3.4e-18 65.0 0.0 1.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBZ53832.1 - 7.8e-17 61.0 0.0 1.3e-16 60.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBZ53832.1 - 2.9e-09 36.6 0.0 5.7e-09 35.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2741 PF10890.3 CBZ53833.1 - 1.2 9.3 3.6 1.3e+02 2.7 0.1 3.6 1 1 4 5 5 5 0 Protein of unknown function (DUF2741) DEAD PF00270.24 CBZ53834.1 - 1.6e-30 105.8 0.0 1.5e-23 83.1 0.0 2.5 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.26 CBZ53834.1 - 6.1e-18 64.4 0.1 1.8e-17 62.9 0.1 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Transglut_core3 PF13471.1 CBZ53834.1 - 0.01 15.6 0.1 0.058 13.1 0.1 2.3 1 0 0 1 1 1 0 Transglutaminase-like superfamily p25-alpha PF05517.7 CBZ53835.1 - 1.1e-42 145.8 2.5 1.4e-42 145.5 1.7 1.0 1 0 0 1 1 1 1 p25-alpha zf-NADH-PPase PF09297.6 CBZ53836.1 - 0.022 14.2 0.1 0.074 12.5 0.1 1.9 1 0 0 1 1 1 0 NADH pyrophosphatase zinc ribbon domain NOB1_Zn_bind PF08772.6 CBZ53836.1 - 0.12 12.2 0.2 0.24 11.2 0.1 1.4 1 0 0 1 1 1 0 Nin one binding (NOB1) Zn-ribbon like HECT PF00632.20 CBZ53837.1 - 3.5e-55 187.4 0.0 5.3e-55 186.8 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Laminin_G_3 PF13385.1 CBZ53837.1 - 8.3e-05 22.8 0.0 0.00023 21.4 0.0 1.6 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily UBA PF00627.26 CBZ53837.1 - 0.0065 16.2 0.0 0.014 15.2 0.0 1.6 1 0 0 1 1 1 1 UBA/TS-N domain SPRY PF00622.23 CBZ53837.1 - 0.58 10.2 0.0 1.5 8.9 0.0 1.6 1 0 0 1 1 1 0 SPRY domain Ras_bdg_2 PF14847.1 CBZ53837.1 - 5 7.1 0.0 14 5.7 0.0 1.7 1 0 0 1 1 1 0 Ras-binding domain of Byr2 Pro_isomerase PF00160.16 CBZ53839.1 - 9.1e-50 168.8 0.1 1.1e-49 168.6 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Aldedh PF00171.17 CBZ53840.1 - 5e-15 54.7 1.9 5e-07 28.4 0.0 2.4 2 1 0 2 2 2 2 Aldehyde dehydrogenase family Trm112p PF03966.11 CBZ53841.1 - 5.5e-16 58.6 0.0 9.8e-16 57.8 0.0 1.4 1 1 0 1 1 1 1 Trm112p-like protein CENP-C_C PF11699.3 CBZ53841.1 - 0.12 12.3 0.0 0.18 11.8 0.0 1.2 1 0 0 1 1 1 0 Mif2/CENP-C like UFD1 PF03152.9 CBZ53842.1 - 3.6e-69 231.4 0.0 4.4e-69 231.1 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 CDC48_2 PF02933.12 CBZ53842.1 - 2e-05 24.1 0.0 0.0001 21.8 0.0 2.0 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 tRNA-synt_2 PF00152.15 CBZ53844.1 - 2.1e-72 243.7 0.0 3.8e-62 210.0 0.0 2.1 2 0 0 2 2 2 2 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 CBZ53844.1 - 1.6e-06 27.8 0.1 4.6e-06 26.3 0.0 1.8 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 CBZ53844.1 - 0.00039 19.7 0.1 0.002 17.3 0.0 1.9 2 0 0 2 2 2 1 tRNA synthetases class II core domain (F) tRNA-synt_2b PF00587.20 CBZ53844.1 - 0.013 15.1 0.0 0.66 9.5 0.0 2.4 2 0 0 2 2 2 0 tRNA synthetase class II core domain (G, H, P, S and T) MCM PF00493.18 CBZ53845.1 - 3.4e-58 197.0 0.0 4e-41 140.9 0.9 3.8 3 1 0 3 3 3 3 MCM2/3/5 family Mg_chelatase PF01078.16 CBZ53845.1 - 1.5e-06 27.5 0.1 0.00016 20.8 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 CBZ53845.1 - 2.1e-05 24.0 0.1 4.7e-05 22.9 0.1 1.5 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_5 PF07728.9 CBZ53845.1 - 0.0027 17.4 0.0 0.0099 15.6 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) G-alpha PF00503.15 CBZ53845.1 - 0.0074 15.0 0.1 0.016 13.9 0.1 1.4 1 0 0 1 1 1 1 G-protein alpha subunit AAA_29 PF13555.1 CBZ53845.1 - 0.011 15.2 0.3 0.032 13.7 0.2 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.22 CBZ53845.1 - 0.03 14.5 1.6 0.72 10.1 0.3 2.4 2 0 0 2 2 2 0 ABC transporter Ribosomal_S13_N PF08069.7 CBZ53846.1 - 2e-27 94.8 0.2 3.6e-27 93.9 0.2 1.5 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.17 CBZ53846.1 - 2e-22 78.7 1.2 2.4e-22 78.5 0.4 1.4 2 0 0 2 2 2 1 Ribosomal protein S15 Clat_adaptor_s PF01217.15 CBZ53847.1 - 3.1e-47 159.8 0.5 2.5e-41 140.7 0.2 2.0 1 1 1 2 2 2 2 Clathrin adaptor complex small chain BTB PF00651.26 CBZ53850.1 - 0.00028 20.8 0.2 0.002 18.1 0.1 2.2 1 1 0 1 1 1 1 BTB/POZ domain Pkinase PF00069.20 CBZ53851.1 - 3.6e-62 209.8 0.0 1.6e-61 207.7 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ53851.1 - 8.5e-26 90.5 5.4 5.6e-20 71.4 3.7 3.1 2 1 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 CBZ53851.1 - 0.0016 17.4 0.0 0.003 16.5 0.0 1.4 1 0 0 1 1 1 1 Kinase-like PP2C PF00481.16 CBZ53852.1 - 1.6e-38 132.5 0.0 9.2e-34 116.9 0.0 2.4 2 0 0 2 2 2 2 Protein phosphatase 2C SpoIIE PF07228.7 CBZ53852.1 - 0.00027 20.7 0.0 0.002 17.8 0.0 2.2 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.1 CBZ53852.1 - 0.0025 17.2 0.8 0.022 14.1 0.0 2.4 2 1 1 3 3 3 1 Protein phosphatase 2C PP-binding_2 PF14573.1 CBZ53853.1 - 2.3e-56 187.7 1.0 3e-56 187.4 0.7 1.1 1 0 0 1 1 1 1 Acyl-carrier PP-binding PF00550.20 CBZ53853.1 - 0.0033 17.6 0.1 0.0059 16.8 0.1 1.4 1 0 0 1 1 1 1 Phosphopantetheine attachment site zf-C3HC4_3 PF13920.1 CBZ53854.1 - 1.6e-07 30.8 6.9 1.6e-07 30.8 4.8 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CBZ53854.1 - 3.6e-07 30.0 11.7 3.6e-07 30.0 8.1 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 CBZ53854.1 - 1.1e-06 28.4 11.9 1.1e-06 28.4 8.3 2.2 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.20 CBZ53854.1 - 1.2e-05 24.8 8.0 1.2e-05 24.8 5.6 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CBZ53854.1 - 4.3e-05 23.2 11.9 4.3e-05 23.2 8.2 2.1 2 0 0 2 2 1 1 Ring finger domain ZZ PF00569.12 CBZ53854.1 - 6e-05 22.4 7.7 6e-05 22.4 5.3 2.2 3 0 0 3 3 2 1 Zinc finger, ZZ type zf-RING_UBOX PF13445.1 CBZ53854.1 - 8.2e-05 22.2 2.9 0.0001 21.9 1.2 1.7 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.1 CBZ53854.1 - 0.00016 21.3 8.9 0.00016 21.3 6.2 2.5 2 0 0 2 2 2 1 zinc-RING finger domain Prok-RING_4 PF14447.1 CBZ53854.1 - 0.006 16.1 6.3 0.006 16.1 4.4 1.8 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_4 PF14570.1 CBZ53854.1 - 0.0096 15.4 5.9 0.0096 15.4 4.1 2.6 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain DUF4187 PF13821.1 CBZ53854.1 - 0.11 12.0 5.3 0.29 10.7 3.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4187) CK1gamma_C PF12605.3 CBZ53855.1 - 0.057 13.9 1.8 0.097 13.2 1.2 1.3 1 0 0 1 1 1 0 Casein kinase 1 gamma C terminal UPF0121 PF03661.8 CBZ53856.1 - 3.4e-07 29.7 6.0 4.8e-07 29.2 4.1 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0121) Tmemb_14 PF03647.8 CBZ53856.1 - 0.45 10.9 0.1 0.45 10.9 0.1 2.9 3 0 0 3 3 3 0 Transmembrane proteins 14C priB_priC PF07445.7 CBZ53859.1 - 6e-05 22.5 2.2 6e-05 22.5 1.5 2.4 2 0 0 2 2 2 1 Primosomal replication protein priB and priC Apolipoprotein PF01442.13 CBZ53859.1 - 0.003 17.1 21.7 0.013 15.0 14.2 2.4 2 1 0 2 2 2 1 Apolipoprotein A1/A4/E domain DUF1887 PF09002.6 CBZ53859.1 - 0.0094 14.3 1.0 0.014 13.8 0.6 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF1887) RecR PF02132.10 CBZ53859.1 - 0.017 14.5 1.4 0.029 13.7 0.1 2.1 2 0 0 2 2 2 0 RecR protein Latarcin PF10279.4 CBZ53859.1 - 0.11 12.6 0.4 0.11 12.6 0.3 2.1 2 1 0 2 2 2 0 Latarcin precursor SpoVR PF04293.8 CBZ53859.1 - 0.58 8.4 5.0 5.2 5.3 0.2 2.1 2 0 0 2 2 2 0 SpoVR like protein Mannosyl_trans2 PF04188.8 CBZ53861.1 - 1.5e-18 66.9 24.6 6.9e-09 35.1 1.4 5.9 6 0 0 6 6 6 5 Mannosyltransferase (PIG-V)) Kinesin PF00225.18 CBZ53862.1 - 7.5e-33 113.6 0.0 4e-26 91.5 0.0 2.3 1 1 1 2 2 2 2 Kinesin motor domain MFS_1 PF07690.11 CBZ53863.1 - 1.4e-06 27.3 27.8 3.5e-05 22.7 4.9 2.8 2 1 1 3 3 3 3 Major Facilitator Superfamily PP2C PF00481.16 CBZ53864.1 - 1.4e-10 40.9 0.7 5.3e-06 26.0 0.0 2.6 3 0 0 3 3 3 2 Protein phosphatase 2C S1 PF00575.18 CBZ53866.1 - 4.6e-10 39.4 0.0 6.4e-07 29.3 0.0 2.4 2 0 0 2 2 2 2 S1 RNA binding domain RAP PF08373.5 CBZ53867.1 - 0.0058 16.3 0.0 0.011 15.5 0.0 1.4 1 0 0 1 1 1 1 RAP domain DIM1 PF02966.11 CBZ53868.1 - 1e-66 222.4 0.3 1.2e-66 222.3 0.2 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin PF00085.15 CBZ53868.1 - 0.0037 16.9 0.1 0.0046 16.6 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin PF00085.15 CBZ53869.1 - 3e-25 87.8 0.3 4.1e-25 87.4 0.2 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_9 PF14595.1 CBZ53869.1 - 1.1e-07 31.5 0.0 1.4e-07 31.1 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 CBZ53869.1 - 2.5e-07 30.8 0.0 1.2e-06 28.6 0.0 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 CBZ53869.1 - 3.2e-07 30.3 0.0 2.3e-05 24.4 0.0 2.3 1 1 1 2 2 2 2 Thioredoxin-like DIM1 PF02966.11 CBZ53869.1 - 2.4e-05 23.8 0.0 3e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Mitosis protein DIM1 Redoxin PF08534.5 CBZ53869.1 - 0.00035 20.1 0.1 0.00046 19.7 0.1 1.3 1 0 0 1 1 1 1 Redoxin DUF953 PF06110.6 CBZ53869.1 - 0.011 15.1 0.5 0.049 13.0 0.4 2.0 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF953) Thioredoxin_4 PF13462.1 CBZ53869.1 - 0.012 15.6 0.0 2.7 7.9 0.0 2.2 1 1 1 2 2 2 0 Thioredoxin TrbC_Ftype PF09673.5 CBZ53869.1 - 0.021 14.4 0.0 0.039 13.5 0.0 1.4 1 0 0 1 1 1 0 Type-F conjugative transfer system pilin assembly protein AhpC-TSA PF00578.16 CBZ53869.1 - 0.029 14.0 0.1 0.043 13.4 0.1 1.3 1 0 0 1 1 1 0 AhpC/TSA family Aldo_ket_red PF00248.16 CBZ53870.1 - 1.2e-51 175.2 0.0 7.4e-51 172.6 0.0 1.9 1 1 0 1 1 1 1 Aldo/keto reductase family AAA_12 PF13087.1 CBZ53871.1 - 1.4e-40 138.7 0.0 1.5e-32 112.6 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_11 PF13086.1 CBZ53871.1 - 9.5e-17 61.3 0.0 1.8e-08 34.2 0.0 3.3 3 0 0 3 3 3 2 AAA domain AAA_30 PF13604.1 CBZ53871.1 - 4.5e-14 52.4 0.0 1.5e-13 50.7 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 CBZ53871.1 - 2.8e-10 39.7 2.7 4e-10 39.3 0.4 2.5 2 0 0 2 2 2 1 Part of AAA domain AAA_22 PF13401.1 CBZ53871.1 - 0.0003 20.9 0.0 0.0015 18.6 0.0 2.2 2 1 0 2 2 1 1 AAA domain UvrD_C_2 PF13538.1 CBZ53871.1 - 0.0026 17.8 0.0 0.0086 16.2 0.0 1.9 2 0 0 2 2 1 1 UvrD-like helicase C-terminal domain PhoH PF02562.11 CBZ53871.1 - 0.0046 16.2 0.0 0.41 9.8 0.0 2.2 2 0 0 2 2 2 1 PhoH-like protein Viral_helicase1 PF01443.13 CBZ53871.1 - 0.0048 16.4 0.1 0.13 11.7 0.0 2.7 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.4 CBZ53871.1 - 0.013 14.4 0.4 0.03 13.3 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) NACHT PF05729.7 CBZ53871.1 - 0.026 14.2 0.0 0.056 13.0 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA PF00004.24 CBZ53871.1 - 0.03 14.5 0.2 0.073 13.2 0.1 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TSP_3 PF02412.13 CBZ53871.1 - 0.1 12.0 0.5 2.4 7.6 0.2 2.3 2 0 0 2 2 2 0 Thrombospondin type 3 repeat Longin PF13774.1 CBZ53872.1 - 3.3e-27 93.8 0.2 4.9e-27 93.3 0.1 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.16 CBZ53872.1 - 3e-16 58.7 0.0 5.3e-16 57.9 0.0 1.4 1 0 0 1 1 1 1 Synaptobrevin PS_Dcarbxylase PF02666.10 CBZ53875.1 - 5.1e-30 104.2 0.0 7.9e-30 103.6 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase Epimerase PF01370.16 CBZ53877.1 - 4.9e-14 52.3 0.0 4.1e-13 49.3 0.0 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 CBZ53877.1 - 0.00021 20.3 0.0 0.00072 18.5 0.0 1.8 2 0 0 2 2 2 1 Male sterility protein DUF4448 PF14610.1 CBZ53877.1 - 0.0086 15.5 3.4 0.015 14.8 2.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) adh_short PF00106.20 CBZ53877.1 - 0.02 14.8 0.7 0.068 13.0 0.0 2.0 2 0 0 2 2 2 0 short chain dehydrogenase RmlD_sub_bind PF04321.12 CBZ53877.1 - 0.026 13.4 0.0 0.22 10.3 0.0 2.4 1 1 0 1 1 1 0 RmlD substrate binding domain DUF912 PF06024.7 CBZ53877.1 - 0.039 13.9 1.2 0.039 13.9 0.8 1.7 2 0 0 2 2 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF4366 PF14283.1 CBZ53877.1 - 0.041 13.2 0.5 0.093 12.1 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) DUF106 PF01956.11 CBZ53877.1 - 0.069 12.6 12.8 0.12 11.9 8.9 1.3 1 0 0 1 1 1 0 Integral membrane protein DUF106 DUF2031 PF09592.5 CBZ53877.1 - 0.092 11.8 8.2 0.17 10.9 5.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2031) MFS_2 PF13347.1 CBZ53877.1 - 0.35 9.1 3.0 0.49 8.7 2.0 1.1 1 0 0 1 1 1 0 MFS/sugar transport protein OATP PF03137.15 CBZ53877.1 - 0.37 8.7 4.2 0.58 8.1 2.9 1.2 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Peptidase_S49_N PF08496.5 CBZ53877.1 - 0.39 10.5 9.0 0.9 9.3 6.3 1.6 1 0 0 1 1 1 0 Peptidase family S49 N-terminal AgrB PF04647.10 CBZ53877.1 - 0.86 8.6 4.1 1.5 7.8 2.8 1.3 1 0 0 1 1 1 0 Accessory gene regulator B DUF3899 PF13038.1 CBZ53877.1 - 1.3 9.2 4.6 2.6 8.2 3.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3899) 7tm_1 PF00001.16 CBZ53877.1 - 1.8 7.6 9.2 2.6 7.1 6.3 1.2 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) O-ag_pol_Wzy PF14296.1 CBZ53877.1 - 2.3 6.6 5.6 3 6.3 3.9 1.1 1 0 0 1 1 1 0 O-antigen polysaccharide polymerase Wzy DUF1765 PF08578.5 CBZ53878.1 - 5.3e-15 55.5 8.2 1.3e-14 54.3 5.7 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1765) C2 PF00168.25 CBZ53878.1 - 0.11 12.2 0.0 0.26 11.1 0.0 1.5 1 0 0 1 1 1 0 C2 domain SecY PF00344.15 CBZ53879.1 - 8.2e-96 320.9 17.6 1e-95 320.6 12.2 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.4 CBZ53879.1 - 6.7e-19 67.0 0.0 2.3e-18 65.3 0.0 2.0 1 0 0 1 1 1 1 Plug domain of Sec61p DUF4381 PF14316.1 CBZ53880.1 - 0.058 13.4 0.0 0.066 13.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) SDP_N PF12278.3 CBZ53880.1 - 0.6 9.7 5.0 0.25 10.9 2.1 1.4 1 1 0 1 1 1 0 Sex determination protein N terminal Caldesmon PF02029.10 CBZ53880.1 - 7.3 4.8 16.5 10 4.4 11.4 1.2 1 0 0 1 1 1 0 Caldesmon 14-3-3 PF00244.15 CBZ53881.1 - 1.4e-20 73.3 3.1 5e-08 32.3 0.0 3.1 3 0 0 3 3 3 3 14-3-3 protein Evr1_Alr PF04777.8 CBZ53882.1 - 1.6e-06 27.9 1.3 0.098 12.5 0.0 3.5 3 0 0 3 3 3 2 Erv1 / Alr family Thioredoxin PF00085.15 CBZ53882.1 - 0.0049 16.5 0.0 0.011 15.4 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin Pex14_N PF04695.8 CBZ53882.1 - 0.055 13.5 0.9 0.17 11.8 0.1 2.2 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Thioredoxin_4 PF13462.1 CBZ53882.1 - 0.24 11.3 0.0 0.24 11.3 0.0 2.4 3 0 0 3 3 3 0 Thioredoxin zf-C2HC5 PF06221.8 CBZ53883.1 - 2e-08 33.8 11.3 4.9e-08 32.6 7.8 1.6 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type ASCH PF04266.9 CBZ53883.1 - 1.4e-06 28.6 0.0 8.6e-06 26.0 0.0 2.4 2 0 0 2 2 2 1 ASCH domain Peptidase_C11 PF03415.9 CBZ53884.1 - 1.3e-24 86.9 0.0 7.3e-23 81.1 0.0 2.1 2 0 0 2 2 2 1 Clostripain family EGF_CA PF07645.10 CBZ53884.1 - 5.8e-16 58.2 17.1 7.3e-10 38.6 2.4 5.1 5 0 0 5 5 5 3 Calcium-binding EGF domain EGF_3 PF12947.2 CBZ53884.1 - 9.8e-13 47.8 46.5 1.2e-07 31.5 3.9 5.4 5 0 0 5 5 5 3 EGF domain cEGF PF12662.2 CBZ53884.1 - 4e-08 32.7 41.4 5.7e-05 22.6 2.3 4.9 4 1 0 4 4 4 3 Complement Clr-like EGF-like Plasmod_Pvs28 PF06247.6 CBZ53884.1 - 0.00058 19.4 7.5 0.00058 19.4 5.2 2.4 2 0 0 2 2 2 1 Plasmodium ookinete surface protein Pvs28 FXa_inhibition PF14670.1 CBZ53884.1 - 0.0014 18.7 6.4 0.0014 18.7 4.5 5.5 5 0 0 5 5 5 3 Coagulation Factor Xa inhibitory site EGF PF00008.22 CBZ53884.1 - 0.0045 16.9 3.1 0.0045 16.9 2.2 5.3 5 0 0 5 5 5 3 EGF-like domain hEGF PF12661.2 CBZ53884.1 - 0.076 13.1 7.9 16 5.8 0.3 4.5 4 0 0 4 4 4 0 Human growth factor-like EGF PS_Dcarbxylase PF02666.10 CBZ53885.1 - 7.3e-15 54.7 0.0 3e-11 43.0 0.0 2.3 1 1 1 2 2 2 2 Phosphatidylserine decarboxylase zf-AN1 PF01428.11 CBZ53886.1 - 4.3e-13 48.9 33.3 3.7e-07 29.9 4.8 3.1 2 1 1 3 3 3 2 AN1-like Zinc finger WD40 PF00400.27 CBZ53887.1 - 4.6e-31 105.5 14.7 2.2e-08 33.6 0.1 5.9 5 0 0 5 5 5 5 WD domain, G-beta repeat Peptidase_M16 PF00675.15 CBZ53888.1 - 1.1e-29 103.1 0.0 3.8e-29 101.3 0.0 1.9 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 CBZ53888.1 - 3.5e-16 59.4 0.0 3.6e-06 26.7 0.0 4.1 4 0 0 4 4 4 3 Peptidase M16 inactive domain DUF2870 PF11069.3 CBZ53889.1 - 0.00032 20.6 0.0 0.00065 19.6 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2870) JAB PF01398.16 CBZ53890.1 - 3.5e-34 116.9 0.0 6.9e-34 116.0 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 CBZ53890.1 - 2.1e-20 72.9 3.5 3.6e-20 72.1 2.5 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.1 CBZ53890.1 - 1.2e-09 37.6 0.0 1.8e-09 37.0 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain GED PF02212.13 CBZ53890.1 - 0.82 9.6 4.4 0.93 9.4 1.4 2.2 2 1 1 3 3 3 0 Dynamin GTPase effector domain RAP PF08373.5 CBZ53891.1 - 1.5e-10 40.7 0.0 2.6e-10 39.9 0.0 1.4 1 0 0 1 1 1 1 RAP domain DUF559 PF04480.7 CBZ53891.1 - 1.5e-05 24.6 0.0 3.4e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF559) NAD_synthase PF02540.12 CBZ53892.1 - 5.2e-26 91.0 0.1 7.3e-15 54.5 0.0 3.0 3 1 0 3 3 3 2 NAD synthase CN_hydrolase PF00795.17 CBZ53892.1 - 2.5e-17 62.8 0.0 6.1e-17 61.5 0.0 1.6 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Arf PF00025.16 CBZ53893.1 - 7.4e-15 54.6 0.0 8.8e-15 54.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Miro PF08477.8 CBZ53893.1 - 1.5e-05 25.4 0.0 2.9e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein SRPRB PF09439.5 CBZ53893.1 - 0.00045 19.4 0.0 0.00064 18.9 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 CBZ53893.1 - 0.00064 19.6 0.0 0.0022 17.9 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.17 CBZ53893.1 - 0.0035 16.7 0.0 0.0044 16.4 0.0 1.2 1 0 0 1 1 1 1 Ras family AAA_33 PF13671.1 CBZ53893.1 - 0.005 16.7 0.1 0.0089 15.9 0.1 1.6 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 CBZ53893.1 - 0.0051 15.8 0.0 0.0082 15.2 0.0 1.2 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 CBZ53893.1 - 0.0073 16.4 0.0 0.012 15.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain cobW PF02492.14 CBZ53893.1 - 0.0098 15.3 0.0 0.086 12.2 0.0 2.2 2 1 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.1 CBZ53893.1 - 0.011 16.0 0.1 0.03 14.6 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.1 CBZ53893.1 - 0.011 16.5 0.1 0.048 14.4 0.0 1.9 2 1 0 2 2 2 0 AAA domain AAA_10 PF12846.2 CBZ53893.1 - 0.014 14.8 0.0 0.022 14.2 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain MobB PF03205.9 CBZ53893.1 - 0.015 15.0 0.0 0.058 13.1 0.0 1.9 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B NACHT PF05729.7 CBZ53893.1 - 0.015 14.9 0.1 0.038 13.6 0.0 1.7 2 0 0 2 2 2 0 NACHT domain AAA PF00004.24 CBZ53893.1 - 0.026 14.7 0.2 0.049 13.8 0.1 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.1 CBZ53893.1 - 0.04 13.8 0.0 0.23 11.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.1 CBZ53893.1 - 0.046 13.7 0.0 0.094 12.6 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_25 PF13481.1 CBZ53893.1 - 0.048 13.0 0.0 0.098 12.0 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.1 CBZ53893.1 - 0.052 13.3 0.0 0.28 10.9 0.0 2.2 3 0 0 3 3 3 0 Part of AAA domain AAA_24 PF13479.1 CBZ53893.1 - 0.06 12.9 0.0 0.082 12.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 CBZ53893.1 - 0.084 12.2 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_5 PF07728.9 CBZ53893.1 - 0.091 12.4 0.0 0.24 11.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) NTPase_1 PF03266.10 CBZ53893.1 - 0.091 12.4 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 NTPase Mg_chelatase PF01078.16 CBZ53893.1 - 0.12 11.4 0.0 0.19 10.8 0.0 1.2 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI TrwB_AAD_bind PF10412.4 CBZ53893.1 - 0.13 10.8 0.2 1.9 7.0 0.0 2.0 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain Gtr1_RagA PF04670.7 CBZ53893.1 - 0.13 11.3 0.0 0.18 10.9 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region MCM PF00493.18 CBZ53893.1 - 0.15 10.8 0.0 0.22 10.2 0.0 1.3 1 0 0 1 1 1 0 MCM2/3/5 family DUF258 PF03193.11 CBZ53893.1 - 0.15 11.2 0.0 0.25 10.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Utp21 PF04192.7 CBZ53894.1 - 4.9e-30 104.3 0.0 8.2e-30 103.6 0.0 1.3 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain WD40 PF00400.27 CBZ53894.1 - 8.4e-13 47.6 12.4 0.00052 19.7 0.0 9.5 9 1 0 9 9 9 4 WD domain, G-beta repeat PQQ_2 PF13360.1 CBZ53894.1 - 1e-08 34.9 0.1 0.00028 20.4 0.0 3.9 1 1 2 3 3 3 2 PQQ-like domain Lgl_C PF08596.5 CBZ53894.1 - 0.067 11.6 0.0 3.1 6.1 0.0 2.6 2 1 1 3 3 3 0 Lethal giant larvae(Lgl) like, C-terminal RAB3GAP2_N PF14655.1 CBZ53894.1 - 0.4 9.6 0.0 2.7 6.9 0.0 2.3 2 1 1 3 3 3 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Chromo PF00385.19 CBZ53895.1 - 4.6e-14 51.8 4.2 8e-11 41.4 0.9 2.4 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain CRCB PF02537.10 CBZ53896.1 - 3.5e-22 78.5 7.4 3.8e-14 52.5 0.3 4.0 3 1 1 4 4 4 3 CrcB-like protein AAA_12 PF13087.1 CBZ53897.1 - 6e-56 188.9 0.0 9.7e-56 188.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 CBZ53897.1 - 1.5e-53 181.8 0.1 6e-53 179.8 0.0 2.0 2 0 0 2 2 2 1 AAA domain R3H PF01424.17 CBZ53897.1 - 7.5e-16 57.5 1.1 5e-15 54.9 0.1 2.6 2 0 0 2 2 2 1 R3H domain AAA_19 PF13245.1 CBZ53897.1 - 2.6e-11 43.1 2.3 7.6e-10 38.4 0.6 3.3 2 0 0 2 2 2 1 Part of AAA domain AAA_30 PF13604.1 CBZ53897.1 - 3.9e-11 42.9 0.4 4.6e-08 32.8 0.0 3.7 4 0 0 4 4 3 1 AAA domain zf-AN1 PF01428.11 CBZ53897.1 - 3.3e-08 33.2 5.2 6.2e-08 32.3 3.6 1.4 1 0 0 1 1 1 1 AN1-like Zinc finger Viral_helicase1 PF01443.13 CBZ53897.1 - 2.6e-07 30.4 0.0 0.035 13.6 0.0 3.2 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase Helicase_RecD PF05127.9 CBZ53897.1 - 3.2e-05 23.6 0.1 0.013 15.1 0.0 3.3 3 0 0 3 3 3 1 Helicase AAA_25 PF13481.1 CBZ53897.1 - 4.9e-05 22.8 0.5 0.0004 19.8 0.0 2.6 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.1 CBZ53897.1 - 6.2e-05 23.1 0.0 0.00057 20.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 CBZ53897.1 - 0.00046 20.2 7.3 0.00098 19.1 0.9 3.4 3 1 0 3 3 3 1 AAA ATPase domain UvrD_C_2 PF13538.1 CBZ53897.1 - 0.001 19.2 0.0 0.0024 17.9 0.0 1.7 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain UvrD_C PF13361.1 CBZ53897.1 - 0.002 17.6 0.0 1.5 8.2 0.0 2.5 2 0 0 2 2 2 2 UvrD-like helicase C-terminal domain FtsK_SpoIIIE PF01580.13 CBZ53897.1 - 0.0043 16.5 0.0 0.017 14.5 0.0 2.0 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_10 PF12846.2 CBZ53897.1 - 0.0052 16.2 0.2 0.039 13.3 0.0 2.6 3 1 0 3 3 3 1 AAA-like domain DUF2075 PF09848.4 CBZ53897.1 - 0.007 15.3 0.0 0.23 10.3 0.0 2.7 3 0 0 3 3 3 1 Uncharacterized conserved protein (DUF2075) AAA_33 PF13671.1 CBZ53897.1 - 0.0092 15.8 0.0 0.027 14.3 0.0 1.9 1 0 0 1 1 1 1 AAA domain ArgK PF03308.11 CBZ53897.1 - 0.018 13.8 0.1 0.085 11.6 0.0 1.9 2 0 0 2 2 2 0 ArgK protein ResIII PF04851.10 CBZ53897.1 - 0.033 14.0 0.0 2.4 7.9 0.0 3.1 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit TrwB_AAD_bind PF10412.4 CBZ53897.1 - 0.046 12.3 0.0 0.082 11.5 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA PF00004.24 CBZ53897.1 - 0.047 13.8 0.0 0.63 10.2 0.0 2.8 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 CBZ53897.1 - 0.066 14.0 1.0 0.61 10.9 1.1 2.6 2 1 0 2 2 1 0 AAA domain CbiA PF01656.18 CBZ53897.1 - 0.22 10.8 0.0 2.5 7.4 0.0 2.3 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain Pkinase PF00069.20 CBZ53898.1 - 2.6e-29 102.1 0.0 2.6e-28 98.8 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ53898.1 - 5.2e-11 42.1 0.0 1.4e-10 40.7 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Choline_kinase PF01633.15 CBZ53898.1 - 0.31 10.5 0.0 0.54 9.8 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kinase-like PF14531.1 CBZ53898.1 - 0.5 9.2 0.0 0.85 8.5 0.0 1.2 1 0 0 1 1 1 0 Kinase-like CENP-Q PF13094.1 CBZ53898.1 - 1.6 8.7 5.5 0.33 10.9 1.0 1.8 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Med26 PF08711.6 CBZ53899.1 - 0.00069 19.0 0.0 0.0012 18.2 0.0 1.5 1 0 0 1 1 1 1 TFIIS helical bundle-like domain NIF PF03031.13 CBZ53900.1 - 8.6e-20 70.9 0.0 1.4e-19 70.3 0.0 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase HAD_2 PF13419.1 CBZ53900.1 - 0.0024 18.1 0.1 0.04 14.1 0.0 2.3 1 1 1 2 2 2 1 Haloacid dehalogenase-like hydrolase BRCT PF00533.21 CBZ53900.1 - 0.0034 17.5 0.0 0.0071 16.4 0.0 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain Rib_recp_KP_reg PF05104.7 CBZ53900.1 - 3.8 8.0 7.6 1.4 9.4 0.1 2.3 2 0 0 2 2 2 0 Ribosome receptor lysine/proline rich region IncA PF04156.9 CBZ53901.1 - 0.0047 16.5 0.3 0.0047 16.5 0.2 6.3 4 1 2 6 6 6 1 IncA protein DUF4496 PF14908.1 CBZ53901.1 - 0.12 12.2 1.1 0.28 11.0 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4496) Reo_sigmaC PF04582.7 CBZ53901.1 - 2.1 7.4 17.5 0.24 10.5 0.3 4.7 2 2 2 5 5 5 0 Reovirus sigma C capsid protein AAA_13 PF13166.1 CBZ53901.1 - 9.1 4.6 30.6 0.023 13.1 1.1 3.4 2 1 0 3 3 3 0 AAA domain Carboxyl_trans PF01039.17 CBZ53902.1 - 9.3e-140 466.2 0.0 1.4e-139 465.6 0.0 1.2 1 0 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.6 CBZ53902.1 - 0.027 13.6 0.1 1.1 8.4 0.0 2.3 2 0 0 2 2 2 0 Malonate decarboxylase gamma subunit (MdcE) Bunya_RdRp PF04196.7 CBZ53903.1 - 3.4 5.5 3.7 4.9 5.0 2.5 1.2 1 0 0 1 1 1 0 Bunyavirus RNA dependent RNA polymerase Helicase_C_3 PF13625.1 CBZ53904.1 - 7.4e-21 74.2 0.0 1.6e-20 73.1 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 CBZ53904.1 - 1.9e-14 53.8 0.0 5.6e-14 52.3 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 CBZ53904.1 - 2.7e-12 46.3 0.0 6.2e-12 45.2 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 CBZ53904.1 - 3.7e-08 32.5 0.0 5.9e-08 31.8 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Y_phosphatase3 PF13350.1 CBZ53904.1 - 0.085 13.1 0.0 0.18 12.0 0.0 1.5 1 0 0 1 1 1 0 Tyrosine phosphatase family LSM14 PF12701.2 CBZ53905.1 - 6.6e-33 112.4 0.0 1e-32 111.7 0.0 1.3 1 0 0 1 1 1 1 Scd6-like Sm domain FDF PF09532.5 CBZ53905.1 - 1.6e-10 41.4 6.0 4e-10 40.1 4.2 1.6 1 1 0 1 1 1 1 FDF domain SM-ATX PF14438.1 CBZ53905.1 - 1.3e-05 25.0 0.0 2e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Ataxin 2 SM domain FAM183 PF14886.1 CBZ53906.1 - 4.1e-14 53.0 0.4 6.4e-14 52.3 0.3 1.3 1 0 0 1 1 1 1 FAM183A and FAM183B related SUZ PF12752.2 CBZ53907.1 - 1.5e-07 31.7 0.2 1.5e-07 31.7 0.2 3.5 2 1 1 3 3 3 1 SUZ domain IFP_35_N PF07334.8 CBZ53909.1 - 0.19 11.7 0.7 1.3 9.0 0.1 2.3 2 0 0 2 2 2 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus Biotin_lipoyl PF00364.17 CBZ53910.1 - 9.7e-17 60.3 0.6 1.4e-16 59.8 0.4 1.2 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.1 CBZ53910.1 - 5.5e-09 35.5 0.0 0.00066 19.2 0.0 2.2 1 1 1 2 2 2 2 Biotin-lipoyl like HlyD_3 PF13437.1 CBZ53910.1 - 5e-08 33.2 0.1 0.011 16.1 0.0 2.2 2 0 0 2 2 2 2 HlyD family secretion protein HlyD PF00529.15 CBZ53910.1 - 2.6e-05 23.7 0.0 0.0022 17.3 0.0 2.1 1 1 1 2 2 2 2 HlyD family secretion protein HlyD_2 PF12700.2 CBZ53910.1 - 7.3e-05 22.0 0.1 0.00082 18.6 0.0 2.0 1 1 1 2 2 2 1 HlyD family secretion protein GCV_H PF01597.14 CBZ53910.1 - 0.0029 17.2 0.2 0.01 15.5 0.1 1.7 1 1 1 2 2 2 1 Glycine cleavage H-protein RnfC_N PF13375.1 CBZ53910.1 - 0.0052 16.4 0.3 0.017 14.8 0.2 1.7 1 1 1 2 2 2 1 RnfC Barrel sandwich hybrid domain DUF2118 PF09891.4 CBZ53910.1 - 0.054 13.2 0.1 0.076 12.7 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2118) 14-3-3 PF00244.15 CBZ53911.1 - 5.8e-64 215.3 0.8 1e-63 214.5 0.5 1.4 1 1 0 1 1 1 1 14-3-3 protein TPR_12 PF13424.1 CBZ53911.1 - 0.27 11.1 3.5 0.25 11.2 0.9 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat Adap_comp_sub PF00928.16 CBZ53912.1 - 7.2e-49 166.2 0.0 1.2e-48 165.5 0.0 1.3 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Metallophos PF00149.23 CBZ53913.1 - 2.3e-25 89.1 0.0 4.2e-25 88.3 0.0 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase EF-hand_6 PF13405.1 CBZ53913.1 - 0.00035 20.2 0.1 0.00098 18.8 0.0 1.7 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.1 CBZ53913.1 - 0.00047 20.2 0.2 0.0011 19.0 0.1 1.6 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.27 CBZ53913.1 - 0.001 18.1 0.0 0.0021 17.2 0.0 1.5 1 0 0 1 1 1 1 EF hand EF-hand_5 PF13202.1 CBZ53913.1 - 0.038 13.3 0.1 0.1 12.0 0.1 1.6 1 0 0 1 1 1 0 EF hand MIP-T3 PF10243.4 CBZ53913.1 - 5.3 5.3 13.8 0.004 15.7 1.5 1.7 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 EF-hand_1 PF00036.27 CBZ53915.1 - 6.3e-21 72.0 0.6 6.9e-07 28.1 0.1 3.6 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.1 CBZ53915.1 - 1.7e-19 69.7 0.1 5.1e-13 48.9 0.0 2.4 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.1 CBZ53915.1 - 2.8e-17 60.9 0.2 2.5e-06 26.8 0.0 3.5 4 0 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.1 CBZ53915.1 - 8.4e-14 50.1 1.6 8.6e-06 24.8 0.0 3.4 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.1 CBZ53915.1 - 1.3e-10 40.6 1.9 3.8e-06 26.4 0.0 3.3 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_9 PF14658.1 CBZ53915.1 - 4.6e-06 26.4 0.0 0.0047 16.8 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain polyprenyl_synt PF00348.12 CBZ53916.1 - 8.3e-22 77.2 0.0 1.4e-18 66.7 0.0 2.2 2 0 0 2 2 2 2 Polyprenyl synthetase Nudix_N_2 PF14803.1 CBZ53918.1 - 0.03 13.9 0.6 2.9 7.6 0.1 2.4 2 0 0 2 2 2 0 Nudix N-terminal GFA PF04828.9 CBZ53918.1 - 0.055 13.4 0.2 11 6.0 0.0 2.3 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme Lar_restr_allev PF14354.1 CBZ53918.1 - 0.15 12.3 0.1 2.3 8.6 0.1 2.2 1 1 1 2 2 2 0 Restriction alleviation protein Lar adh_short PF00106.20 CBZ53919.1 - 3.6e-17 62.7 0.0 5.2e-17 62.2 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CBZ53919.1 - 0.00018 21.2 0.0 0.0003 20.4 0.0 1.3 1 0 0 1 1 1 1 KR domain CRAL_TRIO PF00650.15 CBZ53920.1 - 7e-19 67.8 0.0 1.8e-18 66.5 0.0 1.6 1 1 0 1 1 1 1 CRAL/TRIO domain GOLD_2 PF13897.1 CBZ53920.1 - 0.0027 17.9 0.1 0.019 15.1 0.0 2.2 1 1 1 2 2 2 1 Golgi-dynamics membrane-trafficking CRAL_TRIO_2 PF13716.1 CBZ53920.1 - 0.023 14.6 0.0 0.043 13.7 0.0 1.3 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain Troponin PF00992.15 CBZ53925.1 - 0.067 13.2 0.3 0.11 12.5 0.2 1.3 1 0 0 1 1 1 0 Troponin FUSC_2 PF13515.1 CBZ53926.1 - 5.9e-05 22.9 9.6 5.9e-05 22.9 6.7 3.2 2 1 1 3 3 3 1 Fusaric acid resistance protein-like ALMT PF11744.3 CBZ53926.1 - 0.0031 16.2 2.3 0.0057 15.3 1.6 1.3 1 0 0 1 1 1 1 Aluminium activated malate transporter Lipase_3 PF01764.20 CBZ53928.1 - 2.6e-13 49.7 0.0 4.7e-13 48.9 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Imm12 PF15589.1 CBZ53928.1 - 0.0011 18.7 0.0 0.5 10.1 0.0 2.4 2 0 0 2 2 2 2 Immunity protein 12 CedA PF10729.4 CBZ53928.1 - 0.004 16.6 0.0 0.011 15.2 0.0 1.7 1 0 0 1 1 1 1 Cell division activator CedA GATase_2 PF00310.16 CBZ53928.1 - 0.083 11.5 0.0 0.14 10.8 0.0 1.3 1 0 0 1 1 1 0 Glutamine amidotransferases class-II Secretin_N PF03958.12 CBZ53930.1 - 0.0071 16.5 0.2 0.01 16.0 0.1 1.3 1 0 0 1 1 1 1 Bacterial type II/III secretion system short domain IFT57 PF10498.4 CBZ53930.1 - 0.053 12.2 0.9 0.06 12.0 0.6 1.0 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 Paxillin PF03535.8 CBZ53930.1 - 0.079 12.7 0.0 0.088 12.6 0.0 1.1 1 0 0 1 1 1 0 Paxillin family IL3 PF02059.10 CBZ53930.1 - 0.091 12.7 0.2 0.95 9.4 0.0 2.0 2 0 0 2 2 2 0 Interleukin-3 Baculo_PEP_C PF04513.7 CBZ53930.1 - 0.1 12.3 0.4 0.12 12.1 0.3 1.2 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DASH_Dam1 PF08653.5 CBZ53930.1 - 0.12 12.1 0.1 0.24 11.1 0.1 1.4 1 0 0 1 1 1 0 DASH complex subunit Dam1 Mac PF12464.3 CBZ53930.1 - 0.55 10.2 2.5 1.2 9.2 0.3 2.2 2 1 0 2 2 2 0 Maltose acetyltransferase HALZ PF02183.13 CBZ53930.1 - 0.58 9.9 0.1 0.58 9.9 0.1 2.3 2 0 0 2 2 2 0 Homeobox associated leucine zipper LRR_4 PF12799.2 CBZ53931.1 - 2.3e-10 39.8 7.1 1.4e-06 27.7 2.2 3.3 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CBZ53931.1 - 3.2e-09 36.3 0.6 0.00013 21.5 0.2 3.0 2 1 1 3 3 3 2 Leucine rich repeat LRR_7 PF13504.1 CBZ53931.1 - 3.4e-05 23.3 4.4 7.6 7.2 0.0 4.6 4 0 0 4 4 4 3 Leucine rich repeat LRR_1 PF00560.28 CBZ53931.1 - 8.6e-05 22.0 4.2 1.4 9.2 0.0 4.7 4 1 0 4 4 4 2 Leucine Rich Repeat LRR_6 PF13516.1 CBZ53931.1 - 0.0003 20.5 7.0 0.2 11.8 0.1 4.0 4 0 0 4 4 4 2 Leucine Rich repeat MitMem_reg PF13012.1 CBZ53933.1 - 1.1e-30 106.0 0.3 2e-30 105.2 0.2 1.5 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.16 CBZ53933.1 - 2.9e-26 91.4 0.7 2.8e-25 88.2 0.0 2.2 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Actin PF00022.14 CBZ53934.1 - 6.3e-18 64.3 0.2 2e-06 26.5 0.0 4.0 2 1 1 3 3 3 3 Actin TPR_14 PF13428.1 CBZ53936.1 - 6.9e-26 88.3 15.0 9.1e-05 22.7 0.0 12.1 8 3 4 12 12 12 5 Tetratricopeptide repeat HAT PF02184.11 CBZ53936.1 - 2.7e-23 81.3 56.1 1.5e-05 24.5 0.1 14.7 14 1 0 14 14 14 7 HAT (Half-A-TPR) repeat TPR_16 PF13432.1 CBZ53936.1 - 1.8e-19 69.8 11.0 3.4e-05 24.4 0.1 8.6 8 1 2 10 10 10 5 Tetratricopeptide repeat Suf PF05843.9 CBZ53936.1 - 3.6e-14 53.1 19.3 0.0073 16.0 1.9 6.8 1 1 5 7 7 7 7 Suppressor of forked protein (Suf) TPR_19 PF14559.1 CBZ53936.1 - 1.6e-10 41.1 0.0 0.38 11.1 0.0 7.1 6 2 1 7 7 7 2 Tetratricopeptide repeat TPR_2 PF07719.12 CBZ53936.1 - 1.1e-08 34.3 24.3 1.3 9.1 0.0 10.4 12 0 0 12 12 12 3 Tetratricopeptide repeat TPR_6 PF13174.1 CBZ53936.1 - 1.6e-07 31.2 12.5 1 9.9 0.0 8.8 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_15 PF13429.1 CBZ53936.1 - 1.5e-06 27.4 14.2 0.0067 15.5 1.7 4.6 2 2 2 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.1 CBZ53936.1 - 2.9e-06 26.6 9.9 11 6.1 0.2 7.7 8 0 0 8 8 7 0 Tetratricopeptide repeat TPR_12 PF13424.1 CBZ53936.1 - 9.5e-06 25.4 14.9 7.3 6.6 0.2 8.8 9 1 0 9 9 9 2 Tetratricopeptide repeat TPR_8 PF13181.1 CBZ53936.1 - 2.6e-05 23.6 2.0 3 7.8 0.0 6.6 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_17 PF13431.1 CBZ53936.1 - 0.0021 18.0 1.1 6 7.3 0.0 5.6 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_9 PF13371.1 CBZ53936.1 - 0.0035 17.1 3.8 0.18 11.6 0.0 5.1 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_11 PF13414.1 CBZ53936.1 - 0.0063 16.1 11.7 6.4 6.5 0.1 6.0 5 1 0 6 6 6 1 TPR repeat U3_assoc_6 PF08640.6 CBZ53936.1 - 0.0081 15.9 2.9 0.0081 15.9 2.0 6.2 5 2 2 7 7 7 1 U3 small nucleolar RNA-associated protein 6 Gp_dh_C PF02800.15 CBZ53937.1 - 6.8e-69 230.3 0.0 1.9e-68 228.8 0.0 1.8 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.19 CBZ53937.1 - 2.8e-53 179.9 0.5 6.6e-52 175.4 0.0 2.6 2 0 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain MIF4G PF02854.14 CBZ53938.1 - 9.2e-33 113.4 3.3 1.4e-32 112.8 2.3 1.3 1 0 0 1 1 1 1 MIF4G domain DUF2363 PF10155.4 CBZ53938.1 - 0.066 13.1 0.9 0.92 9.4 0.1 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2363) MA3 PF02847.12 CBZ53938.1 - 0.07 12.8 4.5 0.17 11.6 0.2 2.4 2 0 0 2 2 2 0 MA3 domain HVSL PF09749.4 CBZ53939.1 - 6e-17 61.4 0.2 4.5e-12 45.4 0.0 2.4 2 0 0 2 2 2 2 Uncharacterised conserved protein Peptidase_C48 PF02902.14 CBZ53940.1 - 2.7e-07 30.4 0.0 6.3e-07 29.2 0.0 1.5 2 0 0 2 2 2 1 Ulp1 protease family, C-terminal catalytic domain Fe_hyd_SSU PF02256.12 CBZ53940.1 - 0.025 14.5 0.0 0.14 12.1 0.0 2.0 2 0 0 2 2 2 0 Iron hydrogenase small subunit Cas_APE2256 PF09651.5 CBZ53941.1 - 0.046 13.4 0.2 0.15 11.8 0.1 2.0 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_APE2256) DUF3584 PF12128.3 CBZ53941.1 - 6.8 3.8 30.6 0.095 10.0 5.0 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF3584) bZIP_1 PF00170.16 CBZ53941.1 - 9.7 6.2 17.2 0.18 11.7 0.7 4.3 4 0 0 4 4 4 0 bZIP transcription factor zf-DHHC PF01529.15 CBZ53942.1 - 2.2e-31 108.6 7.2 2.2e-31 108.6 5.0 2.1 1 1 1 2 2 2 1 DHHC palmitoyltransferase TRAPP PF04051.11 CBZ53943.1 - 1.5e-36 125.2 0.0 1.7e-36 125.0 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component adh_short PF00106.20 CBZ53945.1 - 1.6e-19 70.4 0.0 2.3e-19 69.9 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CBZ53945.1 - 1.9e-09 37.6 0.0 2.8e-09 37.0 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CBZ53945.1 - 4.7e-07 29.6 0.0 7.8e-07 28.9 0.0 1.2 1 0 0 1 1 1 1 KR domain 2-Hacid_dh_C PF02826.14 CBZ53945.1 - 0.071 12.2 0.0 0.2 10.7 0.0 1.7 1 1 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Aminotran_3 PF00202.16 CBZ53946.1 - 1.3e-106 356.3 0.0 1.6e-106 356.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III CNH PF00780.17 CBZ53948.1 - 3.8 6.8 0.0 11 5.3 0.0 1.6 2 0 0 2 2 2 0 CNH domain IPK PF03770.11 CBZ53949.1 - 3.5e-05 23.5 0.0 0.0001 22.0 0.0 1.7 1 1 0 1 1 1 1 Inositol polyphosphate kinase NDK PF00334.14 CBZ53950.1 - 2.6e-73 244.1 0.0 1.8e-33 115.1 0.0 3.5 3 0 0 3 3 3 3 Nucleoside diphosphate kinase ADK PF00406.17 CBZ53950.1 - 2.6e-20 72.8 0.0 2.1e-09 37.4 0.0 3.4 3 0 0 3 3 3 2 Adenylate kinase AAA_17 PF13207.1 CBZ53950.1 - 0.00047 20.9 0.0 0.024 15.4 0.0 3.4 3 0 0 3 3 3 1 AAA domain AAA_33 PF13671.1 CBZ53950.1 - 0.014 15.2 0.0 0.13 12.1 0.0 2.8 2 1 0 2 2 2 0 AAA domain AAA_18 PF13238.1 CBZ53950.1 - 0.027 14.7 0.0 0.21 11.8 0.0 2.5 3 0 0 3 3 3 0 AAA domain MSC PF09402.5 CBZ53951.1 - 3.9e-09 35.6 0.9 1.5e-08 33.7 0.1 2.0 2 0 0 2 2 2 1 Man1-Src1p-C-terminal domain ACDC PF14733.1 CBZ53952.1 - 7.3e-20 70.9 0.0 1.1e-19 70.2 0.0 1.3 1 0 0 1 1 1 1 AP2-coincident C-terminal AP2 PF00847.15 CBZ53952.1 - 1.9e-08 34.3 0.7 3.7e-08 33.4 0.5 1.5 1 0 0 1 1 1 1 AP2 domain ABC_tran PF00005.22 CBZ53953.1 - 1.6e-36 125.6 0.0 3e-36 124.7 0.0 1.5 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.18 CBZ53953.1 - 2.4e-16 60.0 3.7 3.7e-16 59.3 2.6 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region AAA_21 PF13304.1 CBZ53953.1 - 7.1e-08 32.7 0.0 0.00032 20.7 0.0 2.3 1 1 0 2 2 2 2 AAA domain SMC_N PF02463.14 CBZ53953.1 - 7e-07 28.7 0.0 2.5e-05 23.6 0.0 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 CBZ53953.1 - 0.00023 21.1 0.1 0.00078 19.4 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain DUF258 PF03193.11 CBZ53953.1 - 0.00037 19.7 0.0 0.00072 18.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_17 PF13207.1 CBZ53953.1 - 0.00037 21.2 0.0 0.00078 20.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.1 CBZ53953.1 - 0.00043 19.7 0.0 0.0014 18.1 0.0 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.1 CBZ53953.1 - 0.0012 18.9 0.0 0.0058 16.7 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 CBZ53953.1 - 0.0048 17.2 0.0 0.013 15.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.18 CBZ53953.1 - 0.0065 16.4 0.0 0.014 15.3 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase MobB PF03205.9 CBZ53953.1 - 0.01 15.5 0.0 0.02 14.6 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B DUF815 PF05673.8 CBZ53953.1 - 0.012 14.5 0.0 0.022 13.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Zeta_toxin PF06414.7 CBZ53953.1 - 0.012 14.7 0.0 0.028 13.4 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_25 PF13481.1 CBZ53953.1 - 0.012 15.0 0.2 0.045 13.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA PF00004.24 CBZ53953.1 - 0.015 15.4 0.1 0.13 12.4 0.0 2.4 2 1 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 CBZ53953.1 - 0.016 15.0 0.0 0.043 13.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 CBZ53953.1 - 0.019 14.4 0.0 0.041 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA-like domain SbcCD_C PF13558.1 CBZ53953.1 - 0.023 14.5 0.3 0.39 10.6 0.2 2.7 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit Miro PF08477.8 CBZ53953.1 - 0.026 14.9 0.0 0.053 14.0 0.0 1.5 1 0 0 1 1 1 0 Miro-like protein AAA_33 PF13671.1 CBZ53953.1 - 0.027 14.3 0.2 0.082 12.7 0.0 2.0 2 1 0 2 2 2 0 AAA domain ABC_membrane_2 PF06472.10 CBZ53953.1 - 0.054 12.6 0.5 0.09 11.8 0.3 1.3 1 0 0 1 1 1 0 ABC transporter transmembrane region 2 AAA_24 PF13479.1 CBZ53953.1 - 0.075 12.6 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 CBZ53953.1 - 0.17 11.6 0.0 0.49 10.1 0.0 1.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) DUF87 PF01935.12 CBZ53953.1 - 0.18 11.5 0.1 0.36 10.6 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function DUF87 NTPase_1 PF03266.10 CBZ53953.1 - 0.21 11.2 0.0 0.39 10.4 0.0 1.4 1 0 0 1 1 1 0 NTPase Septin PF00735.13 CBZ53953.1 - 0.26 10.2 0.0 0.45 9.4 0.0 1.3 1 0 0 1 1 1 0 Septin EMP70 PF02990.11 CBZ53953.1 - 2 6.7 3.0 4.1 5.7 2.1 1.4 1 1 0 1 1 1 0 Endomembrane protein 70 Shadoo PF14999.1 CBZ53957.1 - 1.4 8.7 12.1 0.15 11.8 2.6 2.3 2 0 0 2 2 2 0 Shadow of prion protein, neuroprotective DUF3223 PF11523.3 CBZ53958.1 - 2.6e-11 43.6 0.2 5e-11 42.7 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3223) La PF05383.12 CBZ53958.1 - 2.5e-08 33.6 0.0 5e-08 32.6 0.0 1.5 1 0 0 1 1 1 1 La domain DUF3385 PF11865.3 CBZ53958.1 - 0.046 13.6 0.1 0.1 12.5 0.1 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF3385) DUF45 PF01863.12 CBZ53958.1 - 0.18 11.5 1.9 0.34 10.6 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function DUF45 BTB PF00651.26 CBZ53959.1 - 4.5e-16 58.8 1.6 7.2e-16 58.1 1.1 1.3 1 0 0 1 1 1 1 BTB/POZ domain CLPTM1 PF05602.7 CBZ53959.1 - 0.018 13.7 0.4 0.029 13.1 0.3 1.3 1 0 0 1 1 1 0 Cleft lip and palate transmembrane protein 1 (CLPTM1) ProQ PF04352.8 CBZ53960.1 - 0.05 13.2 0.5 0.2 11.2 0.0 2.0 2 0 0 2 2 2 0 ProQ/FINO family IPK PF03770.11 CBZ53961.1 - 1.6e-34 119.2 0.0 2.1e-34 118.8 0.0 1.2 1 0 0 1 1 1 1 Inositol polyphosphate kinase Peptidase_S24 PF00717.18 CBZ53962.1 - 1.3e-12 47.2 0.0 1.9e-12 46.6 0.0 1.3 1 0 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.4 CBZ53962.1 - 2.9e-05 23.6 0.0 0.0003 20.3 0.0 2.2 1 1 1 2 2 2 1 Signal peptidase, peptidase S26 DWNN PF08783.6 CBZ53963.1 - 9e-05 22.3 0.0 0.00018 21.4 0.0 1.5 1 0 0 1 1 1 1 DWNN domain zf-C3HC4_3 PF13920.1 CBZ53963.1 - 0.015 14.9 9.2 0.032 13.8 6.4 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CBZ53963.1 - 0.088 12.8 11.3 0.2 11.7 7.9 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBZ53963.1 - 0.35 10.6 9.4 0.82 9.4 6.5 1.7 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_2 PF13639.1 CBZ53963.1 - 6.7 6.6 10.6 16 5.4 7.4 1.7 1 0 0 1 1 1 0 Ring finger domain Citrate_synt PF00285.16 CBZ53964.1 - 9.6e-105 350.2 0.0 1.2e-104 349.8 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase TPR_1 PF00515.23 CBZ53966.1 - 3.1e-07 29.7 0.2 1.3e-06 27.7 0.0 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat GFO_IDH_MocA PF01408.17 CBZ53966.1 - 3.8e-07 30.6 0.0 7.9e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold TPR_11 PF13414.1 CBZ53966.1 - 4.4e-07 29.4 0.0 1.1e-06 28.2 0.0 1.6 1 0 0 1 1 1 1 TPR repeat TPR_14 PF13428.1 CBZ53966.1 - 6.4e-06 26.3 0.6 0.017 15.7 0.0 3.6 3 1 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 CBZ53966.1 - 2.3e-05 23.9 0.0 0.00045 19.9 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 CBZ53966.1 - 0.00011 22.0 0.0 0.13 12.2 0.0 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 CBZ53966.1 - 0.00013 21.4 0.0 0.0037 16.9 0.0 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 CBZ53966.1 - 0.00063 19.3 0.1 2.5 8.0 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 CBZ53966.1 - 0.012 15.9 0.0 0.032 14.5 0.0 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_9 PF13371.1 CBZ53966.1 - 0.033 14.0 0.3 4.6 7.1 0.0 2.6 1 1 1 2 2 2 0 Tetratricopeptide repeat Enolase_C PF00113.17 CBZ53967.1 - 8.8e-144 477.9 0.0 1.1e-143 477.6 0.0 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.11 CBZ53967.1 - 8.8e-54 180.9 0.0 1.3e-53 180.3 0.0 1.3 1 0 0 1 1 1 1 Enolase, N-terminal domain MAAL_C PF07476.6 CBZ53967.1 - 0.00024 20.1 0.1 0.0004 19.3 0.0 1.3 1 0 0 1 1 1 1 Methylaspartate ammonia-lyase C-terminus MR_MLE_C PF13378.1 CBZ53967.1 - 0.012 15.5 0.0 0.027 14.4 0.0 1.6 1 0 0 1 1 1 0 Enolase C-terminal domain-like Enolase_C PF00113.17 CBZ53968.1 - 2.8e-151 502.5 0.3 3.4e-151 502.2 0.2 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.11 CBZ53968.1 - 1.4e-54 183.6 0.0 4.4e-54 181.9 0.0 1.8 2 0 0 2 2 2 1 Enolase, N-terminal domain MAAL_C PF07476.6 CBZ53968.1 - 7.3e-06 25.0 0.1 1.6e-05 23.9 0.1 1.5 1 1 0 1 1 1 1 Methylaspartate ammonia-lyase C-terminus MR_MLE_C PF13378.1 CBZ53968.1 - 0.00054 19.9 0.0 0.0016 18.4 0.0 1.8 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE PF01188.16 CBZ53968.1 - 0.1 13.1 0.0 0.23 11.9 0.0 1.6 1 0 0 1 1 1 0 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain MT-A70 PF05063.9 CBZ53969.1 - 1e-47 161.9 0.5 1.2e-22 80.2 0.0 2.2 1 1 0 2 2 2 2 MT-A70 YafO_toxin PF13957.1 CBZ53970.1 - 0.00038 20.2 0.1 0.28 11.0 0.1 2.5 2 0 0 2 2 2 2 Toxin YafO, type II toxin-antitoxin system Solute_trans_a PF03619.11 CBZ53971.1 - 0.0082 15.4 0.3 0.014 14.7 0.2 1.2 1 0 0 1 1 1 1 Organic solute transporter Ostalpha RIC3 PF15361.1 CBZ53971.1 - 0.093 12.9 0.0 0.49 10.6 0.0 2.1 2 0 0 2 2 2 0 Resistance to inhibitors of cholinesterase homologue 3 CK_II_beta PF01214.13 CBZ53972.1 - 4.2e-62 208.9 0.0 5.4e-62 208.5 0.0 1.1 1 0 0 1 1 1 1 Casein kinase II regulatory subunit RAP1 PF07218.6 CBZ53972.1 - 0.25 9.3 0.7 0.35 8.8 0.5 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) PsbQ PF05757.6 CBZ53972.1 - 0.51 9.7 5.3 0.41 10.0 2.2 1.9 2 0 0 2 2 2 0 Oxygen evolving enhancer protein 3 (PsbQ) Sof1 PF04158.9 CBZ53972.1 - 0.54 10.3 2.8 0.28 11.2 0.2 1.8 2 0 0 2 2 2 0 Sof1-like domain DinB_2 PF12867.2 CBZ53974.1 - 0.0076 16.5 0.4 0.039 14.2 0.3 1.9 1 1 0 1 1 1 1 DinB superfamily Apt1 PF10351.4 CBZ53975.1 - 0.2 10.4 0.0 0.2 10.4 0.0 2.6 3 1 0 3 3 3 0 Golgi-body localisation protein domain DSPc PF00782.15 CBZ53976.1 - 8.8e-21 73.8 0.3 1.7e-18 66.4 0.1 3.0 2 1 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 CBZ53976.1 - 0.00037 19.8 0.0 0.0011 18.3 0.0 1.7 2 0 0 2 2 2 1 Protein-tyrosine phosphatase RUN PF02759.14 CBZ53976.1 - 0.024 14.3 0.0 0.051 13.3 0.0 1.6 1 0 0 1 1 1 0 RUN domain DUF3138 PF11336.3 CBZ53976.1 - 0.39 8.8 2.3 0.85 7.7 1.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) DUF948 PF06103.6 CBZ53977.1 - 0.065 13.1 0.1 0.19 11.6 0.1 1.7 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) TFIIE-A_C-term PF11521.3 CBZ53977.1 - 1.1 9.2 7.5 13 5.7 4.1 2.5 2 1 0 2 2 2 0 C-terminal general transcription factor TFIIE alpha Zip PF02535.17 CBZ53977.1 - 8.3 5.3 6.1 11 4.9 4.2 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter RRM_1 PF00076.17 CBZ53978.1 - 4.6e-22 77.4 0.0 6.5e-22 76.9 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBZ53978.1 - 2.1e-17 62.8 0.0 2.9e-17 62.4 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBZ53978.1 - 2.4e-13 49.7 0.0 3.4e-13 49.2 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 CBZ53978.1 - 0.0028 17.4 0.0 0.005 16.6 0.0 1.3 1 0 0 1 1 1 1 RNA binding motif Limkain-b1 PF11608.3 CBZ53978.1 - 0.08 12.7 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Limkain b1 Cmc1 PF08583.5 CBZ53979.1 - 1.1e-07 31.5 5.3 1.1e-07 31.5 3.7 1.7 2 0 0 2 2 2 1 Cytochrome c oxidase biogenesis protein Cmc1 like CHCH PF06747.8 CBZ53979.1 - 0.094 12.6 1.3 0.24 11.3 0.9 1.7 1 1 0 1 1 1 0 CHCH domain Glutaredoxin PF00462.19 CBZ53980.1 - 1.8e-11 43.8 0.0 2.8e-11 43.2 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin YIF1 PF03878.10 CBZ53981.1 - 2.9e-28 98.6 1.6 5e-26 91.3 1.1 2.2 2 0 0 2 2 2 2 YIF1 GTP_EFTU PF00009.22 CBZ53982.1 - 2.3e-43 147.8 0.0 4.3e-43 146.9 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.19 CBZ53982.1 - 7.5e-14 51.3 0.0 1.3e-13 50.5 0.0 1.4 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.1 CBZ53982.1 - 3.7e-07 29.9 0.0 8.6e-07 28.7 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_IV PF03764.13 CBZ53982.1 - 1.6e-05 24.4 0.0 3.8e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G, domain IV HTH_16 PF12645.2 CBZ53982.1 - 0.075 12.9 0.0 0.25 11.2 0.0 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain DUF3729 PF12526.3 CBZ53983.1 - 9.9 7.5 10.6 5e+02 2.0 7.3 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF3729) OTU PF02338.14 CBZ53984.1 - 0.0092 16.5 0.0 0.086 13.4 0.0 2.4 2 1 0 2 2 2 1 OTU-like cysteine protease Mito_fiss_reg PF05308.6 CBZ53986.1 - 0.054 12.8 1.6 0.076 12.3 1.1 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.14 CBZ53986.1 - 0.061 12.6 0.2 0.07 12.4 0.1 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Dscam_C PF12355.3 CBZ53986.1 - 0.061 13.5 0.0 0.071 13.3 0.0 1.1 1 0 0 1 1 1 0 Down syndrome cell adhesion molecule C terminal AAA_2 PF07724.9 CBZ53988.1 - 2e-50 171.0 1.9 5e-47 159.9 0.0 3.0 3 0 0 3 3 2 2 AAA domain (Cdc48 subfamily) AAA PF00004.24 CBZ53988.1 - 1.5e-23 83.4 0.9 9.8e-14 51.6 0.0 3.1 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.4 CBZ53988.1 - 1.6e-22 79.2 2.3 1.9e-22 78.9 0.1 2.5 2 0 0 2 2 1 1 C-terminal, D2-small domain, of ClpB protein Clp_N PF02861.15 CBZ53988.1 - 3.4e-17 62.1 0.4 4.2e-11 42.6 0.1 3.0 2 0 0 2 2 2 2 Clp amino terminal domain AAA_5 PF07728.9 CBZ53988.1 - 1.6e-15 57.0 0.3 2.4e-09 37.0 0.0 4.2 4 1 0 4 4 4 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 CBZ53988.1 - 2.4e-11 43.9 8.1 0.00022 21.2 0.0 5.8 5 1 1 6 6 6 2 AAA ATPase domain IstB_IS21 PF01695.12 CBZ53988.1 - 1.1e-09 37.9 0.1 0.0049 16.3 0.0 3.5 3 0 0 3 3 3 2 IstB-like ATP binding protein AAA_22 PF13401.1 CBZ53988.1 - 1.8e-09 37.8 0.9 0.0023 18.0 0.0 4.4 2 2 1 3 3 3 2 AAA domain AAA_17 PF13207.1 CBZ53988.1 - 1.7e-08 35.3 1.9 0.0014 19.3 0.0 3.7 2 1 0 2 2 2 2 AAA domain Sigma54_activat PF00158.21 CBZ53988.1 - 1.2e-07 31.4 0.0 0.0003 20.3 0.0 2.7 2 1 0 2 2 2 2 Sigma-54 interaction domain Arch_ATPase PF01637.13 CBZ53988.1 - 1.2e-07 31.7 6.0 0.029 14.0 0.0 4.4 3 2 0 5 5 4 2 Archaeal ATPase AAA_14 PF13173.1 CBZ53988.1 - 1.2e-07 31.6 0.0 0.024 14.5 0.0 3.0 2 1 0 2 2 2 2 AAA domain AAA_18 PF13238.1 CBZ53988.1 - 3.3e-07 30.6 3.1 0.013 15.8 0.0 3.0 3 0 0 3 3 2 2 AAA domain RNA_helicase PF00910.17 CBZ53988.1 - 5.3e-05 23.3 0.0 0.086 13.0 0.0 2.8 2 0 0 2 2 2 1 RNA helicase NACHT PF05729.7 CBZ53988.1 - 7.9e-05 22.3 0.0 0.15 11.7 0.0 3.2 3 0 0 3 3 3 1 NACHT domain DNA_pol3_delta2 PF13177.1 CBZ53988.1 - 0.00018 21.1 0.0 0.0076 15.9 0.0 3.0 3 0 0 3 3 3 1 DNA polymerase III, delta subunit ABC_tran PF00005.22 CBZ53988.1 - 0.00037 20.7 0.7 0.058 13.6 0.0 3.5 3 0 0 3 3 3 1 ABC transporter Mg_chelatase PF01078.16 CBZ53988.1 - 0.00048 19.3 0.1 3.1 6.8 0.0 3.4 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_28 PF13521.1 CBZ53988.1 - 0.00049 20.0 0.1 0.44 10.4 0.0 3.1 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.1 CBZ53988.1 - 0.00052 19.6 0.5 1 8.9 0.0 2.9 3 0 0 3 3 3 2 AAA domain AAA_19 PF13245.1 CBZ53988.1 - 0.00054 19.6 0.1 0.76 9.5 0.1 2.9 2 0 0 2 2 2 1 Part of AAA domain Zeta_toxin PF06414.7 CBZ53988.1 - 0.00089 18.4 0.5 0.09 11.8 0.0 3.1 3 1 0 3 3 3 1 Zeta toxin AAA_25 PF13481.1 CBZ53988.1 - 0.001 18.5 0.0 1.6 8.1 0.0 3.1 3 0 0 3 3 2 1 AAA domain T2SE PF00437.15 CBZ53988.1 - 0.0017 17.2 0.2 0.031 13.1 0.1 2.6 2 1 0 2 2 2 1 Type II/IV secretion system protein MobB PF03205.9 CBZ53988.1 - 0.0041 16.8 0.0 0.22 11.2 0.0 2.8 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B DUF258 PF03193.11 CBZ53988.1 - 0.0047 16.1 0.0 0.7 9.0 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_10 PF12846.2 CBZ53988.1 - 0.0059 16.0 0.0 0.3 10.4 0.0 2.9 2 1 1 3 3 3 1 AAA-like domain NTPase_1 PF03266.10 CBZ53988.1 - 0.011 15.4 0.1 12 5.5 0.0 3.3 3 0 0 3 3 3 0 NTPase AAA_33 PF13671.1 CBZ53988.1 - 0.014 15.3 0.0 1.3 8.8 0.0 2.9 2 0 0 2 2 2 0 AAA domain UPF0079 PF02367.12 CBZ53988.1 - 0.017 14.7 0.0 1.6 8.3 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 ResIII PF04851.10 CBZ53988.1 - 0.019 14.7 2.5 2.1 8.1 0.0 4.1 3 1 0 3 3 3 0 Type III restriction enzyme, res subunit MMR_HSR1 PF01926.18 CBZ53988.1 - 0.039 13.8 0.0 14 5.6 0.0 2.9 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_3 PF07726.6 CBZ53988.1 - 0.04 13.5 0.0 15 5.1 0.0 3.3 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) V_ATPase_I PF01496.14 CBZ53988.1 - 0.042 11.7 6.6 0.069 10.9 4.6 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Miro PF08477.8 CBZ53988.1 - 0.054 13.9 0.0 13 6.3 0.0 3.1 2 0 0 2 2 2 0 Miro-like protein Ras PF00071.17 CBZ53988.1 - 0.1 11.9 0.0 11 5.3 0.0 2.8 2 0 0 2 2 2 0 Ras family ATP_bind_1 PF03029.12 CBZ53988.1 - 0.17 11.4 0.5 7.6 5.9 0.0 3.2 4 0 0 4 4 4 0 Conserved hypothetical ATP binding protein BING4CT PF08149.6 CBZ53989.1 - 4e-31 106.3 0.0 9e-31 105.2 0.0 1.6 1 0 0 1 1 1 1 BING4CT (NUC141) domain WD40 PF00400.27 CBZ53989.1 - 5.9e-05 22.7 0.2 0.0043 16.8 0.1 3.6 4 0 0 4 4 4 1 WD domain, G-beta repeat DUF155 PF02582.9 CBZ53990.1 - 1e-51 175.3 0.0 1.5e-51 174.8 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 ENOD93 PF03386.9 CBZ53992.1 - 0.24 11.1 1.6 0.48 10.1 1.1 1.7 1 1 0 1 1 1 0 Early nodulin 93 ENOD93 protein DNA_pol_E_B PF04042.11 CBZ53993.1 - 4.3e-13 48.9 0.4 7.6e-13 48.1 0.3 1.3 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Rhomboid PF01694.17 CBZ53994.1 - 7.5e-29 100.6 12.2 2e-28 99.2 8.5 1.7 1 0 0 1 1 1 1 Rhomboid family zf-CCCH PF00642.19 CBZ53996.1 - 1.7e-16 59.4 29.9 5.5e-06 25.9 1.4 4.9 4 1 0 4 4 4 4 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 CBZ53996.1 - 8.5e-06 25.5 30.9 0.00061 19.6 2.8 4.1 4 0 0 4 4 4 3 Zinc finger C-x8-C-x5-C-x3-H type XPG_N PF00752.12 CBZ53997.1 - 1.8e-25 89.1 0.0 5e-25 87.7 0.0 1.8 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.13 CBZ53997.1 - 6.2e-25 87.0 0.2 1.6e-24 85.7 0.0 1.9 2 0 0 2 2 2 1 XPG I-region XPG_I_2 PF12813.2 CBZ53997.1 - 0.00019 21.0 0.5 0.00052 19.5 0.0 1.9 2 0 0 2 2 2 1 XPG domain containing DUF1387 PF07139.6 CBZ53998.1 - 0.075 12.6 0.9 0.16 11.5 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1387) DUF4460 PF14687.1 CBZ53999.1 - 5.4e-05 22.9 0.0 0.0022 17.7 0.0 2.9 2 1 0 2 2 2 1 Domain of unknown function (DUF4460) DUF4461 PF14688.1 CBZ53999.1 - 0.013 14.8 0.0 0.049 12.9 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4461) gag-asp_proteas PF13975.1 CBZ54000.1 - 0.0019 17.9 0.2 0.013 15.3 0.0 2.2 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 CBZ54000.1 - 0.006 17.0 0.0 0.017 15.5 0.0 1.8 2 0 0 2 2 2 1 Aspartyl protease RVP PF00077.15 CBZ54000.1 - 0.011 15.5 0.0 0.11 12.3 0.0 2.3 2 0 0 2 2 2 0 Retroviral aspartyl protease Asp_protease PF09668.5 CBZ54000.1 - 0.15 11.6 0.0 3.4 7.2 0.0 2.6 3 0 0 3 3 3 0 Aspartyl protease RRM_1 PF00076.17 CBZ54001.1 - 8e-10 38.2 0.0 5.3e-05 22.7 0.0 3.3 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBZ54001.1 - 8e-09 35.3 0.0 0.00023 21.0 0.0 3.4 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBZ54001.1 - 0.00013 21.7 0.0 0.03 14.1 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ASXH PF13919.1 CBZ54001.1 - 0.9 9.3 0.0 1.8 8.3 0.0 1.4 1 0 0 1 1 1 0 Asx homology domain FAT PF02259.18 CBZ54002.1 - 9.6e-20 70.8 0.1 2.3e-19 69.5 0.1 1.7 1 1 0 1 1 1 1 FAT domain PI3_PI4_kinase PF00454.22 CBZ54002.1 - 7.6e-10 38.6 0.1 5.7e-06 25.9 0.0 2.3 2 0 0 2 2 2 2 Phosphatidylinositol 3- and 4-kinase ParcG PF10274.4 CBZ54002.1 - 6 6.7 0.0 19 5.0 0.0 1.8 1 0 0 1 1 1 0 Parkin co-regulated protein WD40 PF00400.27 CBZ54003.1 - 0.0082 15.9 3.5 0.66 9.9 0.0 3.5 4 0 0 4 4 4 2 WD domain, G-beta repeat Glyco_tran_28_C PF04101.11 CBZ54004.1 - 2.9e-17 62.8 0.0 1.5e-12 47.4 0.0 2.2 2 0 0 2 2 2 2 Glycosyltransferase family 28 C-terminal domain Glyco_trans_1_3 PF13528.1 CBZ54004.1 - 0.05 12.7 0.0 0.073 12.2 0.0 1.1 1 0 0 1 1 1 0 Glycosyl transferase family 1 TRAPPC9-Trs120 PF08626.6 CBZ54005.1 - 1.1e-18 66.1 1.0 5.7e-07 27.3 0.2 4.5 4 0 0 4 4 4 4 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit Med3 PF11593.3 CBZ54005.1 - 0.3 10.3 0.4 0.93 8.6 0.3 1.8 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal zf-RING_2 PF13639.1 CBZ54007.1 - 0.065 13.0 9.0 0.11 12.2 0.1 4.4 4 0 0 4 4 4 0 Ring finger domain Tme5_EGF_like PF09064.5 CBZ54007.1 - 1 9.0 20.9 1.6 8.4 2.4 6.7 7 1 0 7 7 7 0 Thrombomodulin like fifth domain, EGF-like DEAD PF00270.24 CBZ54008.1 - 4.4e-34 117.4 0.0 1e-33 116.2 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CBZ54008.1 - 1.8e-17 62.9 0.2 3.9e-17 61.8 0.2 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 CBZ54008.1 - 1.7e-05 24.7 0.0 3e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.1 CBZ54008.1 - 0.00034 20.3 0.6 0.0013 18.4 0.4 2.1 1 1 0 1 1 1 1 Part of AAA domain Helicase_C_2 PF13307.1 CBZ54008.1 - 0.071 13.0 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 Helicase C-terminal domain Peptidase_C15 PF01470.12 CBZ54009.1 - 1.1e-22 80.9 0.0 1.5e-18 67.4 0.0 2.2 2 0 0 2 2 2 2 Pyroglutamyl peptidase Chromo PF00385.19 CBZ54009.1 - 2.4e-08 33.5 1.3 5.4e-08 32.3 0.9 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain WD40 PF00400.27 CBZ54012.1 - 1.4e-20 72.3 9.8 3.4e-06 26.7 0.0 6.4 6 0 0 6 6 6 6 WD domain, G-beta repeat cEGF PF12662.2 CBZ54014.1 - 0.23 11.1 13.1 7.2 6.3 0.0 5.7 5 0 0 5 5 5 0 Complement Clr-like EGF-like Pkinase PF00069.20 CBZ54016.1 - 1.2e-56 191.7 0.0 2.6e-56 190.6 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ54016.1 - 6.2e-32 110.6 0.0 1.5e-30 106.1 0.0 2.6 2 1 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 CBZ54016.1 - 4.2e-08 32.4 0.0 5.1e-05 22.3 0.0 2.4 2 0 0 2 2 2 2 Kinase-like RIO1 PF01163.17 CBZ54016.1 - 0.00048 19.5 0.0 0.00084 18.7 0.0 1.5 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.9 CBZ54016.1 - 0.0005 19.1 0.1 0.00089 18.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CBZ54016.1 - 0.0068 16.1 0.0 0.0068 16.1 0.0 2.6 2 1 0 2 2 2 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 CBZ54016.1 - 0.04 13.2 0.0 0.11 11.7 0.0 1.7 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Seadorna_VP7 PF07387.6 CBZ54016.1 - 0.12 11.1 0.0 0.19 10.5 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 RRM_1 PF00076.17 CBZ54017.1 - 1.8e-52 174.8 0.8 2.4e-17 62.2 0.1 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBZ54017.1 - 5.2e-38 128.8 1.4 3.1e-12 46.2 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBZ54017.1 - 5.4e-31 106.2 2.8 3.8e-10 39.4 0.1 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WW PF00397.21 CBZ54017.1 - 2.4e-09 36.9 5.6 4.1e-09 36.1 3.9 1.4 1 0 0 1 1 1 1 WW domain RNA_bind PF08675.6 CBZ54017.1 - 0.00016 21.5 0.1 0.0016 18.4 0.0 2.5 3 0 0 3 3 3 1 RNA binding domain Nup35_RRM PF05172.8 CBZ54017.1 - 0.00029 20.5 0.1 0.057 13.1 0.0 3.1 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif DUF1469 PF07332.6 CBZ54018.1 - 0.091 12.4 0.3 0.17 11.6 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1469) FA_desaturase PF00487.19 CBZ54019.1 - 1.2 8.4 8.4 0.13 11.6 0.2 2.6 2 0 0 2 2 2 0 Fatty acid desaturase MFS_1 PF07690.11 CBZ54022.1 - 3.1e-27 95.2 21.1 2.1e-19 69.4 1.4 3.1 2 1 1 3 3 3 3 Major Facilitator Superfamily Sugar_tr PF00083.19 CBZ54022.1 - 3.1e-21 75.5 0.0 2e-14 53.0 0.0 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter OATP PF03137.15 CBZ54022.1 - 1.7e-12 46.2 4.6 0.0035 15.4 0.2 4.2 2 2 2 4 4 4 3 Organic Anion Transporter Polypeptide (OATP) family Nuc_H_symport PF03825.11 CBZ54022.1 - 0.035 12.8 7.5 0.7 8.5 2.9 2.1 2 0 0 2 2 2 0 Nucleoside H+ symporter Folate_carrier PF01770.13 CBZ54022.1 - 0.22 9.9 0.0 0.49 8.8 0.0 1.5 1 0 0 1 1 1 0 Reduced folate carrier Pkinase PF00069.20 CBZ54023.1 - 2.7e-06 26.7 0.0 0.22 10.6 0.0 4.0 4 0 0 4 4 4 3 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ54023.1 - 0.0057 15.7 0.0 0.73 8.8 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase KBP_C PF12309.3 CBZ54024.1 - 4.6e-35 121.2 9.5 9.6e-33 113.6 1.8 3.5 2 1 1 3 3 3 2 KIF-1 binding protein C terminal DUF267 PF03268.9 CBZ54024.1 - 0.029 13.2 0.1 0.047 12.5 0.1 1.2 1 0 0 1 1 1 0 Caenorhabditis protein of unknown function, DUF267 TPR_12 PF13424.1 CBZ54024.1 - 2.4 8.1 11.1 4 7.4 0.2 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat DEK_C PF08766.6 CBZ54025.1 - 0.2 11.4 0.0 0.41 10.4 0.0 1.5 1 0 0 1 1 1 0 DEK C terminal domain DEK_C PF08766.6 CBZ54026.1 - 9.1e-05 22.1 0.2 0.61 9.9 0.0 2.4 2 0 0 2 2 2 2 DEK C terminal domain MRP-S24 PF14955.1 CBZ54026.1 - 0.54 10.1 1.3 49 3.7 0.0 2.8 3 0 0 3 3 3 0 Mitochondrial ribosome subunit S24 DEK_C PF08766.6 CBZ54027.1 - 0.00066 19.4 0.3 2.2 8.1 0.0 2.8 3 0 0 3 3 3 2 DEK C terminal domain MRP-S24 PF14955.1 CBZ54027.1 - 0.047 13.5 0.4 13 5.6 0.0 2.4 2 0 0 2 2 2 0 Mitochondrial ribosome subunit S24 CAP160 PF07918.6 CBZ54027.1 - 0.15 11.6 0.0 10 5.8 0.1 3.1 3 0 0 3 3 3 0 CAP160 repeat DUF605 PF04652.11 CBZ54027.1 - 1.4 8.1 38.5 1.1 8.5 3.8 3.2 3 0 0 3 3 3 0 Vta1 like DEAD PF00270.24 CBZ54028.1 - 1.3e-10 41.0 0.0 3.4e-09 36.4 0.0 2.6 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CBZ54028.1 - 4.5e-09 36.0 0.0 1.8e-08 34.0 0.0 2.1 1 1 0 1 1 1 1 Helicase conserved C-terminal domain PAN_1 PF00024.21 CBZ54029.1 - 2e-25 88.3 29.1 1.1e-08 34.7 2.5 4.2 2 1 2 4 4 4 4 PAN domain PAN_4 PF14295.1 CBZ54029.1 - 9.1e-23 79.7 27.7 9.9e-11 41.1 1.7 4.7 5 0 0 5 5 5 4 PAN domain PAN_3 PF08277.7 CBZ54029.1 - 3.6e-10 39.3 15.8 0.00058 19.4 0.6 4.4 4 0 0 4 4 4 4 PAN-like domain PAN_2 PF08276.6 CBZ54029.1 - 3.3e-08 33.2 27.5 0.012 15.4 0.2 4.5 4 0 0 4 4 4 4 PAN-like domain RRM_5 PF13893.1 CBZ54029.1 - 0.061 13.1 0.1 0.21 11.4 0.0 1.9 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MANEC PF07502.9 CBZ54029.1 - 2 8.4 25.5 1.3 9.0 0.6 4.7 3 1 2 5 5 5 0 MANEC domain CarbpepA_inh PF02977.10 CBZ54029.1 - 4.7 6.8 19.7 0.11 12.1 0.8 3.4 3 0 0 3 3 3 0 Carboxypeptidase A inhibitor PAN_1 PF00024.21 CBZ54030.1 - 1.3e-25 88.9 24.7 4.6e-08 32.7 1.4 4.2 3 1 1 4 4 4 4 PAN domain PAN_4 PF14295.1 CBZ54030.1 - 3.8e-20 71.3 26.6 5.8e-07 29.1 0.5 4.7 5 0 0 5 5 5 4 PAN domain PAN_3 PF08277.7 CBZ54030.1 - 7.4e-06 25.4 20.1 7e-05 22.3 0.2 4.4 4 1 0 4 4 4 3 PAN-like domain PAN_2 PF08276.6 CBZ54030.1 - 0.00021 21.0 25.3 0.084 12.7 2.3 4.4 4 0 0 4 4 4 4 PAN-like domain TACI-CRD2 PF09305.5 CBZ54030.1 - 0.042 13.6 6.6 0.11 12.2 0.4 3.2 3 0 0 3 3 3 0 TACI, cysteine-rich domain PAN_1 PF00024.21 CBZ54031.1 - 4.8e-24 83.9 28.9 1.1e-08 34.7 2.5 4.2 2 1 2 4 4 4 4 PAN domain PAN_4 PF14295.1 CBZ54031.1 - 1.7e-22 78.8 24.9 1.1e-09 37.8 1.6 4.7 5 0 0 5 5 5 4 PAN domain PAN_3 PF08277.7 CBZ54031.1 - 2.3e-09 36.7 18.4 0.00058 19.4 0.6 4.5 4 0 0 4 4 4 4 PAN-like domain PAN_2 PF08276.6 CBZ54031.1 - 5.5e-08 32.5 27.0 0.012 15.4 0.2 4.5 4 0 0 4 4 4 4 PAN-like domain RRM_5 PF13893.1 CBZ54031.1 - 0.065 13.0 0.1 0.21 11.4 0.0 1.8 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CarbpepA_inh PF02977.10 CBZ54031.1 - 3.1 7.4 19.4 0.11 12.1 0.8 3.4 3 0 0 3 3 3 0 Carboxypeptidase A inhibitor MANEC PF07502.9 CBZ54031.1 - 3.2 7.8 25.0 2 8.4 0.5 4.8 3 1 2 5 5 5 0 MANEC domain WD40 PF00400.27 CBZ54032.1 - 3.4e-16 58.4 7.3 0.00033 20.4 0.4 6.0 5 1 0 5 5 5 3 WD domain, G-beta repeat ATG16 PF08614.6 CBZ54032.1 - 7e-05 22.7 11.4 0.00017 21.4 7.9 1.7 1 1 0 1 1 1 1 Autophagy protein 16 (ATG16) Atg14 PF10186.4 CBZ54032.1 - 3.6 6.4 11.8 5.7 5.7 8.2 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 YL1 PF05764.8 CBZ54032.1 - 4.3 6.8 13.3 7.2 6.1 9.2 1.3 1 0 0 1 1 1 0 YL1 nuclear protein V_ATPase_I PF01496.14 CBZ54032.1 - 5.3 4.7 9.4 7.6 4.2 6.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Rhomboid PF01694.17 CBZ54033.1 - 1.1e-29 103.3 15.6 1.1e-29 103.3 10.8 1.6 2 0 0 2 2 2 1 Rhomboid family DER1 PF04511.10 CBZ54033.1 - 0.022 14.2 5.7 0.043 13.3 3.9 1.7 1 1 0 1 1 1 0 Der1-like family DUF1751 PF08551.5 CBZ54033.1 - 0.13 12.6 0.4 0.13 12.6 0.3 2.3 3 0 0 3 3 3 0 Eukaryotic integral membrane protein (DUF1751) GAF PF01590.21 CBZ54034.1 - 1.2e-12 48.1 0.0 2e-12 47.4 0.0 1.3 1 0 0 1 1 1 1 GAF domain GAF_3 PF13492.1 CBZ54034.1 - 5.4e-07 29.7 0.0 9.1e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 GAF domain GAF_2 PF13185.1 CBZ54034.1 - 8.3e-07 29.5 0.0 1.6e-06 28.6 0.0 1.4 1 0 0 1 1 1 1 GAF domain DPM2 PF07297.7 CBZ54035.1 - 0.048 13.9 0.0 0.063 13.5 0.0 1.1 1 0 0 1 1 1 0 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) Pribosyltran PF00156.22 CBZ54036.1 - 3.4e-19 68.7 0.0 4.4e-19 68.4 0.0 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain PRTase_2 PF15609.1 CBZ54036.1 - 0.076 12.3 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 Phosphoribosyl transferase PEN-2 PF10251.4 CBZ54036.1 - 0.1 12.8 0.0 0.23 11.6 0.0 1.5 1 0 0 1 1 1 0 Presenilin enhancer-2 subunit of gamma secretase SATase_N PF06426.9 CBZ54037.1 - 0.12 12.6 1.4 0.35 11.1 1.0 1.7 1 0 0 1 1 1 0 Serine acetyltransferase, N-terminal DUF1811 PF08838.5 CBZ54037.1 - 0.74 9.8 3.7 0.42 10.5 0.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1811) DUF904 PF06005.7 CBZ54037.1 - 2.6 8.4 30.0 6.3e+02 0.7 0.0 4.9 3 1 0 3 3 3 0 Protein of unknown function (DUF904) KIAA1430 PF13879.1 CBZ54038.1 - 7.9e-19 67.9 0.0 1.4e-18 67.0 0.0 1.4 1 0 0 1 1 1 1 KIAA1430 homologue UPF0240 PF06784.6 CBZ54038.1 - 0.024 14.3 0.7 0.042 13.5 0.5 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0240) CNRIP1 PF15043.1 CBZ54038.1 - 0.076 12.2 0.0 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 CB1 cannabinoid receptor-interacting protein 1 Peptidase_S8 PF00082.17 CBZ54039.1 - 7.1e-42 143.4 2.2 1.1e-41 142.8 1.5 1.3 1 0 0 1 1 1 1 Subtilase family Cu-binding_MopE PF11617.3 CBZ54039.1 - 0.016 14.9 2.7 0.043 13.6 1.8 1.8 1 0 0 1 1 1 0 Protein metal binding site Prenyltrans PF00432.16 CBZ54041.1 - 4.5e-34 115.6 14.9 3e-11 42.6 0.7 5.2 5 0 0 5 5 5 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 CBZ54041.1 - 4.1e-16 59.3 0.0 2.1e-07 31.3 0.0 3.3 2 1 1 3 3 3 3 Prenyltransferase-like Myb_DNA-binding PF00249.26 CBZ54042.1 - 7.6e-23 80.3 0.3 1.9e-10 40.6 0.0 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 CBZ54042.1 - 3.6e-22 78.2 0.5 1.7e-15 56.8 0.0 2.9 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.1 CBZ54042.1 - 0.011 15.8 0.0 0.032 14.3 0.0 1.8 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain EF-hand_7 PF13499.1 CBZ54043.1 - 6.5e-08 32.5 0.4 5.1e-05 23.3 0.4 3.5 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_6 PF13405.1 CBZ54043.1 - 0.0014 18.3 1.8 2 8.5 0.2 4.2 4 0 0 4 4 4 2 EF-hand domain EF-hand_1 PF00036.27 CBZ54043.1 - 0.0026 16.9 0.6 0.22 10.9 0.3 3.4 3 0 0 3 3 3 1 EF hand EF-hand_8 PF13833.1 CBZ54043.1 - 0.078 12.6 0.7 4.3 7.0 0.1 3.2 3 0 0 3 3 3 0 EF-hand domain pair dCMP_cyt_deam_1 PF00383.17 CBZ54045.1 - 7.1e-23 80.1 2.1 1.5e-22 79.1 1.5 1.5 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region DUF1084 PF06454.6 CBZ54046.1 - 0.11 11.5 4.4 0.058 12.4 1.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1084) DivIVA PF05103.8 CBZ54047.1 - 0.2 11.6 1.6 0.4 10.7 1.1 1.4 1 0 0 1 1 1 0 DivIVA protein UPF0047 PF01894.12 CBZ54049.1 - 5.6e-09 35.8 0.0 5.1e-07 29.5 0.0 3.3 3 1 0 3 3 3 1 Uncharacterised protein family UPF0047 Glycos_transf_2 PF00535.21 CBZ54050.1 - 0.11 12.1 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 2 CRAL_TRIO PF00650.15 CBZ54051.1 - 0.0053 16.2 0.0 0.012 15.1 0.0 1.6 1 1 0 1 1 1 1 CRAL/TRIO domain Pkinase PF00069.20 CBZ54052.1 - 3.8e-73 245.8 0.0 5.5e-73 245.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ54052.1 - 5.6e-36 123.9 0.0 8.1e-36 123.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.24 CBZ54052.1 - 2.3e-13 50.2 0.0 3.9e-13 49.5 0.0 1.4 1 0 0 1 1 1 1 PH domain EF-hand_1 PF00036.27 CBZ54052.1 - 5.1e-11 41.0 0.4 0.00045 19.3 0.0 3.6 3 0 0 3 3 3 2 EF hand EF-hand_5 PF13202.1 CBZ54052.1 - 3.1e-09 35.7 0.7 0.0024 17.1 0.0 3.5 3 0 0 3 3 3 2 EF hand Kinase-like PF14531.1 CBZ54052.1 - 2.8e-08 33.0 0.0 1.1e-06 27.8 0.0 2.2 2 0 0 2 2 2 1 Kinase-like EF-hand_6 PF13405.1 CBZ54052.1 - 6.6e-08 31.8 0.3 0.0046 16.7 0.0 3.0 3 0 0 3 3 2 2 EF-hand domain EF-hand_8 PF13833.1 CBZ54052.1 - 4.8e-07 29.3 1.7 0.032 13.8 0.0 3.2 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_7 PF13499.1 CBZ54052.1 - 5e-06 26.5 1.3 3.8e-05 23.7 0.1 2.8 2 1 0 2 2 2 1 EF-hand domain pair Kdo PF06293.9 CBZ54052.1 - 0.0022 17.1 0.0 0.004 16.2 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 CBZ54052.1 - 0.0083 15.4 0.2 0.015 14.6 0.1 1.3 1 0 0 1 1 1 1 RIO1 family PH_8 PF15409.1 CBZ54052.1 - 0.045 13.8 0.2 0.11 12.6 0.2 1.6 1 1 0 1 1 1 0 Pleckstrin homology domain Pox_ser-thr_kin PF05445.6 CBZ54052.1 - 0.068 11.9 0.1 0.1 11.3 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase YrbL-PhoP_reg PF10707.4 CBZ54052.1 - 0.44 9.8 0.0 0.81 8.9 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Cid2 PF09774.4 CBZ54052.1 - 1.2 9.1 2.5 2.2 8.3 1.8 1.3 1 0 0 1 1 1 0 Caffeine-induced death protein 2 Nuc_sug_transp PF04142.10 CBZ54053.1 - 0.067 12.2 0.0 0.13 11.2 0.0 1.4 1 0 0 1 1 1 0 Nucleotide-sugar transporter UPF0086 PF01868.11 CBZ54054.1 - 9.2e-14 50.8 0.1 1.6e-13 50.0 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function UPF0086 Taq-exonuc PF09281.5 CBZ54054.1 - 0.023 14.8 0.2 0.054 13.6 0.2 1.6 1 0 0 1 1 1 0 Taq polymerase, exonuclease Lactamase_B PF00753.22 CBZ54055.1 - 0.047 13.3 0.1 0.66 9.5 0.1 2.5 2 0 0 2 2 2 0 Metallo-beta-lactamase superfamily LURAP PF14854.1 CBZ54055.1 - 2.2 7.9 6.9 6.5 6.4 1.5 2.9 2 0 0 2 2 2 0 Leucine rich adaptor protein PI3_PI4_kinase PF00454.22 CBZ54056.1 - 4.7e-33 114.6 0.0 1.1e-32 113.4 0.0 1.6 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase GCD14_N PF14801.1 CBZ54056.1 - 0.59 9.7 0.0 1.5 8.4 0.0 1.6 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit N-term Mito_carr PF00153.22 CBZ54057.1 - 9.3e-51 169.5 5.0 1.6e-16 59.7 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF3816 PF12822.2 CBZ54057.1 - 0.015 15.1 1.4 0.045 13.6 0.3 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF3816) Na_Ca_ex PF01699.19 CBZ54057.1 - 0.042 13.4 1.7 0.13 11.8 0.0 2.1 2 0 0 2 2 2 0 Sodium/calcium exchanger protein SbcCD_C PF13558.1 CBZ54057.1 - 0.062 13.2 0.1 0.2 11.6 0.0 1.9 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit DUF2076 PF09849.4 CBZ54057.1 - 0.28 11.2 3.9 6.4 6.7 0.9 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2076) VIT1 PF01988.14 CBZ54057.1 - 5.9 6.3 8.1 33 3.8 2.7 3.0 2 1 1 3 3 3 0 VIT family zf-H2C2_2 PF13465.1 CBZ54058.1 - 0.35 11.2 1.5 34 4.9 0.2 2.6 2 0 0 2 2 2 0 Zinc-finger double domain zf-C2H2_4 PF13894.1 CBZ54058.1 - 9.6 6.8 14.1 0.25 11.7 2.6 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger Sec7 PF01369.15 CBZ54059.1 - 9.7e-56 188.4 0.2 3e-55 186.8 0.0 1.9 2 0 0 2 2 2 1 Sec7 domain DUF1981 PF09324.5 CBZ54059.1 - 5.3e-17 61.1 0.3 2e-16 59.2 0.2 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1981) Sec7_N PF12783.2 CBZ54059.1 - 8.3e-16 57.8 0.2 8.3e-16 57.8 0.1 3.9 4 0 0 4 4 4 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF3149 PF11346.3 CBZ54059.1 - 0.31 10.6 0.3 0.65 9.6 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3149) Symplekin_C PF12295.3 CBZ54059.1 - 0.91 9.4 0.0 2 8.3 0.0 1.5 1 0 0 1 1 1 0 Symplekin tight junction protein C terminal Ycf1 PF05758.7 CBZ54059.1 - 2 6.0 0.3 5.3 4.6 0.2 1.7 1 0 0 1 1 1 0 Ycf1 Ins145_P3_rec PF08709.6 CBZ54061.1 - 0.021 13.8 0.0 1.8 7.5 0.0 2.2 2 0 0 2 2 2 0 Inositol 1,4,5-trisphosphate/ryanodine receptor PBP PF01161.15 CBZ54062.1 - 4.5e-10 39.5 0.0 5.6e-10 39.2 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Ank_4 PF13637.1 CBZ54063.1 - 2.6e-35 120.1 2.0 1.4e-12 47.7 0.1 4.3 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.25 CBZ54063.1 - 4.4e-33 111.4 4.8 5e-10 38.6 0.0 4.9 5 0 0 5 5 5 4 Ankyrin repeat Ank_2 PF12796.2 CBZ54063.1 - 3.2e-31 107.5 0.8 6.3e-19 68.0 0.0 2.9 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.1 CBZ54063.1 - 1.2e-25 87.0 0.1 1.9e-07 30.6 0.0 4.4 4 0 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.1 CBZ54063.1 - 2.7e-24 84.6 2.4 4.4e-10 39.4 0.0 3.2 1 1 2 3 3 3 3 Ankyrin repeats (many copies) PDEase_I PF00233.14 CBZ54065.1 - 1e-45 156.3 0.0 5.1e-45 154.0 0.0 1.9 2 0 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase BCIP PF13862.1 CBZ54066.1 - 7e-39 133.3 0.0 1.2e-38 132.6 0.0 1.3 1 0 0 1 1 1 1 p21-C-terminal region-binding protein BUD22 PF09073.5 CBZ54066.1 - 2.9 6.8 16.8 4.7 6.1 11.6 1.4 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.7 CBZ54066.1 - 9.6 3.9 19.3 14 3.4 13.4 1.2 1 0 0 1 1 1 0 Nop14-like family Ribosomal_L15e PF00827.12 CBZ54067.1 - 2.6e-95 317.4 11.2 3e-95 317.2 7.8 1.0 1 0 0 1 1 1 1 Ribosomal L15 Secretin_N_2 PF07655.8 CBZ54068.1 - 4.8 7.6 7.7 25 5.3 1.4 3.5 4 0 0 4 4 4 0 Secretin N-terminal domain Pkinase PF00069.20 CBZ54071.1 - 1.2e-29 103.2 0.0 2.6e-24 85.8 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ54071.1 - 1.1e-12 47.5 0.0 2.9e-06 26.5 0.0 2.2 1 1 1 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 CBZ54071.1 - 0.018 14.0 0.0 0.024 13.5 0.0 1.2 1 0 0 1 1 1 0 Kinase-like TTL PF03133.10 CBZ54072.1 - 1.3e-79 267.1 0.2 1.6e-55 188.1 0.2 2.2 2 0 0 2 2 2 2 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.1 CBZ54072.1 - 4.8e-06 25.5 0.0 0.00023 20.0 0.0 2.5 2 0 0 2 2 2 1 YheC/D like ATP-grasp ATP-grasp_3 PF02655.9 CBZ54072.1 - 0.055 13.3 0.0 1.1 9.1 0.0 2.3 2 0 0 2 2 2 0 ATP-grasp domain ATPgrasp_ST PF14397.1 CBZ54072.1 - 0.11 11.6 0.0 3.9 6.4 0.0 2.2 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp PX PF00787.19 CBZ54073.1 - 3.3e-11 42.9 0.0 6.6e-11 42.0 0.0 1.4 1 0 0 1 1 1 1 PX domain WD40 PF00400.27 CBZ54073.1 - 2.2e-09 36.8 0.1 0.05 13.5 0.2 5.5 5 0 0 5 5 5 3 WD domain, G-beta repeat COX5B PF01215.14 CBZ54073.1 - 0.025 14.2 0.0 0.046 13.3 0.0 1.4 1 0 0 1 1 1 0 Cytochrome c oxidase subunit Vb RICTOR_M PF14666.1 CBZ54074.1 - 1.3e-10 40.6 0.0 0.0002 20.4 0.0 2.3 2 0 0 2 2 2 2 Rapamycin-insensitive companion of mTOR, middle domain RICTOR_V PF14668.1 CBZ54074.1 - 0.0079 16.1 0.1 4.1 7.3 0.0 2.7 2 0 0 2 2 2 2 Rapamycin-insensitive companion of mTOR, domain 5 RICTOR_N PF14664.1 CBZ54074.1 - 0.054 12.0 0.1 0.096 11.2 0.1 1.3 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR, N-term DUF866 PF05907.8 CBZ54074.1 - 2 7.8 0.0 3.6 7.0 0.0 1.3 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF866) F-box PF00646.28 CBZ54075.1 - 0.0059 16.2 4.0 0.0063 16.1 0.6 2.7 2 0 0 2 2 2 1 F-box domain S1-P1_nuclease PF02265.11 CBZ54076.1 - 1.6e-26 93.4 0.0 5.4e-20 72.0 0.0 2.1 2 0 0 2 2 2 2 S1/P1 Nuclease FKBP_C PF00254.23 CBZ54077.1 - 1.9e-22 79.0 0.0 3.4e-22 78.2 0.0 1.4 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Cortexin PF11057.3 CBZ54077.1 - 0.15 11.7 0.0 0.32 10.6 0.0 1.6 1 0 0 1 1 1 0 Cortexin of kidney GTP_EFTU PF00009.22 CBZ54078.1 - 2.1e-26 92.4 0.0 3.9e-26 91.6 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 CBZ54078.1 - 4e-08 33.1 0.2 0.012 15.4 0.0 2.4 2 0 0 2 2 2 2 Translation-initiation factor 2 MMR_HSR1 PF01926.18 CBZ54078.1 - 6.5e-05 22.8 0.0 0.00014 21.8 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.20 CBZ54078.1 - 0.06 13.4 2.7 3.9 7.6 0.4 3.1 2 0 0 2 2 2 0 Elongation factor Tu domain 2 SRPRB PF09439.5 CBZ54078.1 - 0.26 10.5 0.0 13 4.9 0.0 2.2 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit Miro PF08477.8 CBZ54078.1 - 0.29 11.6 0.0 5.7 7.4 0.0 2.4 1 1 0 1 1 1 0 Miro-like protein NIF PF03031.13 CBZ54080.1 - 8.3e-15 54.7 0.1 1e-11 44.7 0.0 2.4 2 0 0 2 2 2 2 NLI interacting factor-like phosphatase PTCB-BRCT PF12738.2 CBZ54080.1 - 9.7e-07 28.5 0.0 2e-06 27.5 0.0 1.6 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.21 CBZ54080.1 - 0.0044 17.1 0.0 0.0082 16.2 0.0 1.4 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain RBFA PF02033.13 CBZ54081.1 - 1.7e-11 44.0 0.1 4.6e-11 42.6 0.0 1.8 2 0 0 2 2 2 1 Ribosome-binding factor A DUF3134 PF11332.3 CBZ54081.1 - 0.051 13.7 0.3 0.13 12.4 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3134) ACT PF01842.20 CBZ54081.1 - 0.064 12.7 0.0 0.14 11.6 0.0 1.5 1 0 0 1 1 1 0 ACT domain DUF418 PF04235.7 CBZ54082.1 - 0.012 15.3 2.6 0.016 14.8 1.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF418) 5TM-5TMR_LYT PF07694.7 CBZ54082.1 - 0.054 12.8 0.4 0.081 12.2 0.3 1.2 1 0 0 1 1 1 0 5TMR of 5TMR-LYT DctQ PF04290.7 CBZ54082.1 - 0.18 11.5 6.1 0.24 11.1 4.2 1.1 1 0 0 1 1 1 0 Tripartite ATP-independent periplasmic transporters, DctQ component DUF814 PF05670.8 CBZ54083.1 - 2.7e-20 72.0 0.0 8e-20 70.5 0.0 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF814) PcfK PF14058.1 CBZ54083.1 - 0.73 9.9 8.2 1.5 8.9 5.7 1.5 1 0 0 1 1 1 0 PcfK-like protein DUF1764 PF08576.5 CBZ54083.1 - 2.3 9.0 8.7 3.9 8.2 6.0 1.3 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) Abhydrolase_2 PF02230.11 CBZ54084.1 - 1e-41 142.7 0.0 3.6e-34 118.1 0.0 2.1 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.2 CBZ54084.1 - 2.3e-13 50.5 1.9 3.1e-12 46.8 1.3 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CBZ54084.1 - 5.1e-13 48.9 0.0 6.7e-13 48.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 CBZ54084.1 - 0.00017 21.2 0.0 0.00031 20.3 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Esterase_phd PF10503.4 CBZ54084.1 - 0.00023 20.4 0.0 0.00038 19.7 0.0 1.3 1 0 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.16 CBZ54084.1 - 0.00027 20.2 0.0 0.00041 19.6 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family FSH1 PF03959.8 CBZ54084.1 - 0.00092 18.7 0.0 0.0072 15.7 0.0 2.4 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Esterase PF00756.15 CBZ54084.1 - 0.046 13.1 0.0 0.073 12.4 0.0 1.3 1 0 0 1 1 1 0 Putative esterase Abhydrolase_1 PF00561.15 CBZ54084.1 - 0.076 12.5 0.0 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold AXE1 PF05448.7 CBZ54084.1 - 0.16 10.4 0.0 0.23 9.9 0.0 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) GTP_EFTU PF00009.22 CBZ54085.1 - 1e-30 106.5 0.0 4e-30 104.6 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 CBZ54085.1 - 4.2e-11 42.6 0.0 7.2e-11 41.9 0.0 1.3 1 0 0 1 1 1 1 Translation-initiation factor 2 MMR_HSR1 PF01926.18 CBZ54085.1 - 2.7e-06 27.3 0.0 5.4e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 CBZ54085.1 - 9.8e-05 22.8 0.0 0.0043 17.5 0.0 2.6 1 1 0 1 1 1 1 Miro-like protein Dynamin_N PF00350.18 CBZ54085.1 - 0.00012 21.9 0.1 0.00034 20.4 0.1 1.9 1 1 0 1 1 1 1 Dynamin family Ras PF00071.17 CBZ54085.1 - 0.037 13.4 0.0 0.4 10.0 0.0 2.1 2 0 0 2 2 2 0 Ras family PduV-EutP PF10662.4 CBZ54085.1 - 0.037 13.5 0.3 1.5 8.2 0.0 2.9 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation DLIC PF05783.6 CBZ54085.1 - 0.094 11.3 0.1 0.18 10.4 0.0 1.4 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) cobW PF02492.14 CBZ54085.1 - 0.13 11.6 0.1 4.6 6.6 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain zf-MYND PF01753.13 CBZ54088.1 - 4.3e-10 39.2 18.6 4.3e-10 39.2 12.9 1.8 2 0 0 2 2 2 1 MYND finger AAA PF00004.24 CBZ54089.1 - 2.8e-42 144.0 0.0 5.5e-42 143.0 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.9 CBZ54089.1 - 2.3e-07 30.9 0.1 8.8e-06 25.7 0.0 2.5 3 0 0 3 3 2 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 CBZ54089.1 - 5.6e-07 29.3 0.0 2.8e-06 27.1 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 CBZ54089.1 - 2.6e-06 27.5 0.1 8.6e-05 22.5 0.0 2.5 2 1 1 3 3 3 1 AAA ATPase domain AAA_22 PF13401.1 CBZ54089.1 - 4.9e-06 26.7 0.3 0.00095 19.3 0.0 2.7 2 1 0 2 2 1 1 AAA domain RuvB_N PF05496.7 CBZ54089.1 - 6.6e-06 25.3 0.0 1.3e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus IstB_IS21 PF01695.12 CBZ54089.1 - 0.0005 19.5 0.0 0.0011 18.4 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_17 PF13207.1 CBZ54089.1 - 0.00082 20.1 0.2 0.0024 18.6 0.0 2.1 2 1 0 2 2 1 1 AAA domain TIP49 PF06068.8 CBZ54089.1 - 0.0012 17.5 0.5 0.0022 16.7 0.0 1.6 2 0 0 2 2 2 1 TIP49 C-terminus Zeta_toxin PF06414.7 CBZ54089.1 - 0.0017 17.5 0.0 0.0042 16.2 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin AAA_14 PF13173.1 CBZ54089.1 - 0.0018 18.1 0.0 0.0035 17.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 CBZ54089.1 - 0.0026 17.9 0.0 0.005 16.9 0.0 1.5 1 0 0 1 1 1 1 RNA helicase Mg_chelatase PF01078.16 CBZ54089.1 - 0.0029 16.8 0.0 0.0065 15.6 0.0 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI DUF4200 PF13863.1 CBZ54089.1 - 0.0035 17.2 4.3 0.0073 16.2 2.9 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4200) AAA_19 PF13245.1 CBZ54089.1 - 0.0044 16.7 0.0 0.01 15.6 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain Sigma54_activat PF00158.21 CBZ54089.1 - 0.0045 16.4 0.1 0.014 14.8 0.0 2.0 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_3 PF07726.6 CBZ54089.1 - 0.005 16.4 0.0 0.01 15.4 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.8 CBZ54089.1 - 0.0057 15.5 0.0 0.011 14.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_18 PF13238.1 CBZ54089.1 - 0.0058 16.9 0.0 0.031 14.5 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA_28 PF13521.1 CBZ54089.1 - 0.0066 16.4 0.0 0.016 15.1 0.0 1.7 2 0 0 2 2 1 1 AAA domain PhoH PF02562.11 CBZ54089.1 - 0.008 15.4 0.0 0.016 14.4 0.0 1.5 1 0 0 1 1 1 1 PhoH-like protein AAA_33 PF13671.1 CBZ54089.1 - 0.01 15.7 0.0 0.045 13.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain Sigma54_activ_2 PF14532.1 CBZ54089.1 - 0.01 15.9 0.0 0.06 13.3 0.0 2.2 3 0 0 3 3 2 0 Sigma-54 interaction domain AAA_25 PF13481.1 CBZ54089.1 - 0.01 15.2 0.2 0.069 12.5 0.0 2.1 1 1 0 2 2 2 0 AAA domain AAA_24 PF13479.1 CBZ54089.1 - 0.014 14.9 0.1 0.028 14.0 0.1 1.5 1 0 0 1 1 1 0 AAA domain Phage_GP20 PF06810.6 CBZ54089.1 - 0.017 14.5 2.1 0.27 10.6 1.2 2.2 2 0 0 2 2 2 0 Phage minor structural protein GP20 Parvo_NS1 PF01057.12 CBZ54089.1 - 0.02 13.7 0.0 0.038 12.8 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Med4 PF10018.4 CBZ54089.1 - 0.025 13.9 1.2 0.058 12.7 0.8 1.5 1 0 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 KaiC PF06745.8 CBZ54089.1 - 0.025 13.6 0.0 0.069 12.2 0.0 1.7 2 0 0 2 2 2 0 KaiC Arch_ATPase PF01637.13 CBZ54089.1 - 0.029 14.0 0.3 0.17 11.5 0.0 2.4 2 1 0 2 2 2 0 Archaeal ATPase UPF0079 PF02367.12 CBZ54089.1 - 0.033 13.8 0.0 0.061 12.9 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_11 PF13086.1 CBZ54089.1 - 0.035 13.6 0.2 0.2 11.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 CBZ54089.1 - 0.035 13.7 0.1 0.21 11.2 0.0 2.1 1 1 2 3 3 3 0 NACHT domain IncA PF04156.9 CBZ54089.1 - 0.43 10.1 2.7 0.81 9.2 1.9 1.4 1 0 0 1 1 1 0 IncA protein V-ATPase_G PF03179.10 CBZ54090.1 - 1.2e-07 31.9 8.3 3.4e-07 30.5 5.8 1.7 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit HrpE PF06188.7 CBZ54090.1 - 0.013 15.2 10.4 0.014 15.1 6.5 1.6 1 1 1 2 2 2 0 HrpE/YscL/FliH and V-type ATPase subunit E RapA_C PF12137.3 CBZ54090.1 - 0.061 12.1 4.7 0.094 11.5 3.3 1.2 1 0 0 1 1 1 0 RNA polymerase recycling family C-terminal DUF3552 PF12072.3 CBZ54090.1 - 0.063 12.4 12.2 0.13 11.4 8.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) F-protein PF00469.15 CBZ54090.1 - 0.42 9.9 9.7 0.048 13.0 2.4 2.2 2 0 0 2 2 2 0 Negative factor, (F-Protein) or Nef ATP-synt_B PF00430.13 CBZ54090.1 - 9.3 6.0 20.0 0.18 11.6 9.1 1.6 2 0 0 2 2 2 0 ATP synthase B/B' CF(0) JAB PF01398.16 CBZ54091.1 - 2.3e-13 49.8 0.1 8.5e-13 48.0 0.0 1.9 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 CBZ54091.1 - 2.5e-09 37.2 0.0 4.6e-09 36.3 0.0 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function COX15-CtaA PF02628.10 CBZ54092.1 - 3e-78 262.7 12.4 3.5e-78 262.5 8.6 1.0 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein Peripla_BP_3 PF13377.1 CBZ54092.1 - 0.13 12.2 0.2 5.6 6.9 0.1 2.3 2 0 0 2 2 2 0 Periplasmic binding protein-like domain Metallophos PF00149.23 CBZ54094.1 - 3.9e-06 26.4 1.7 8.7e-06 25.2 1.2 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase START PF01852.14 CBZ54096.1 - 5.7e-07 29.0 0.1 1.5e-06 27.7 0.0 1.6 1 0 0 1 1 1 1 START domain DNMT1-RFD PF12047.3 CBZ54097.1 - 2.5e-08 33.7 0.5 1e-07 31.7 0.2 2.2 2 0 0 2 2 2 1 Cytosine specific DNA methyltransferase replication foci domain Auxin_resp PF06507.8 CBZ54097.1 - 4.1e-05 23.3 0.0 0.00013 21.7 0.0 1.8 1 0 0 1 1 1 1 Auxin response factor Tmemb_14 PF03647.8 CBZ54098.1 - 3.1e-08 33.8 10.9 3.6e-08 33.7 7.6 1.1 1 0 0 1 1 1 1 Transmembrane proteins 14C WD40 PF00400.27 CBZ54099.1 - 0.0047 16.7 12.0 8.7 6.4 0.0 7.4 7 0 0 7 7 7 3 WD domain, G-beta repeat Dus PF01207.12 CBZ54100.1 - 2e-48 164.8 0.0 3.2e-48 164.1 0.0 1.3 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) B-block_TFIIIC PF04182.7 CBZ54101.1 - 1.1e-09 37.9 0.0 5.4e-09 35.7 0.0 2.2 2 0 0 2 2 2 1 B-block binding subunit of TFIIIC HTH_5 PF01022.15 CBZ54101.1 - 0.00076 19.0 0.0 0.0084 15.7 0.0 2.5 2 0 0 2 2 2 1 Bacterial regulatory protein, arsR family Rrf2 PF02082.15 CBZ54101.1 - 0.051 13.7 0.3 7.2 6.8 0.0 4.2 5 0 0 5 5 5 0 Transcriptional regulator RNA_pol_Rpc34 PF05158.7 CBZ54101.1 - 0.58 9.2 0.0 1.1 8.4 0.0 1.3 1 0 0 1 1 1 0 RNA polymerase Rpc34 subunit DUF2217 PF10265.4 CBZ54103.1 - 2.1 6.9 4.6 3 6.4 3.2 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) FHA PF00498.21 CBZ54104.1 - 1.6e-16 60.1 0.0 2.9e-16 59.3 0.0 1.4 1 0 0 1 1 1 1 FHA domain Rotamase PF00639.16 CBZ54104.1 - 4.7e-14 52.8 0.0 1.4e-13 51.4 0.0 1.9 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.1 CBZ54104.1 - 7.8e-08 32.5 0.0 2.8e-07 30.7 0.0 1.9 1 1 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.1 CBZ54104.1 - 0.1 13.2 0.0 0.1 13.2 0.0 3.0 3 1 0 3 3 3 0 PPIC-type PPIASE domain DUF3552 PF12072.3 CBZ54104.1 - 0.14 11.3 6.0 0.26 10.4 4.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) TPT PF03151.11 CBZ54105.1 - 2.1e-05 24.1 0.0 4.3e-05 23.2 0.0 1.7 1 0 0 1 1 1 1 Triose-phosphate Transporter family Ammonium_transp PF00909.16 CBZ54105.1 - 0.021 13.3 0.1 0.032 12.7 0.1 1.2 1 0 0 1 1 1 0 Ammonium Transporter Family MitMem_reg PF13012.1 CBZ54106.1 - 9.7e-05 22.4 0.2 0.00016 21.7 0.2 1.6 1 1 0 1 1 1 1 Maintenance of mitochondrial structure and function zf-met PF12874.2 CBZ54107.1 - 4.8e-05 23.4 0.5 9.6e-05 22.4 0.4 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type CactinC_cactus PF09732.4 CBZ54107.1 - 0.0015 18.1 0.8 0.0022 17.6 0.2 1.5 2 0 0 2 2 2 1 Cactus-binding C-terminus of cactin protein CDK2AP PF09806.4 CBZ54109.1 - 0.011 16.0 5.9 0.011 16.0 4.1 2.2 2 0 0 2 2 2 0 Cyclin-dependent kinase 2-associated protein Bac_DNA_binding PF00216.16 CBZ54110.1 - 5.7e-25 87.1 0.0 8.1e-25 86.6 0.0 1.2 1 0 0 1 1 1 1 Bacterial DNA-binding protein DUF4496 PF14908.1 CBZ54110.1 - 0.00053 19.8 0.0 0.0014 18.5 0.0 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF4496) DUF2780 PF11075.3 CBZ54110.1 - 0.024 14.7 1.5 0.038 14.0 1.1 1.2 1 0 0 1 1 1 0 Protein of unknown function VcgC/VcgE (DUF2780) PCI PF01399.22 CBZ54111.1 - 2e-16 60.2 2.2 2.5e-16 59.8 0.1 2.2 2 0 0 2 2 2 1 PCI domain Apc5 PF12862.2 CBZ54111.1 - 1.8 8.4 7.0 6.3 6.7 0.0 3.3 4 0 0 4 4 4 0 Anaphase-promoting complex subunit 5 14-3-3 PF00244.15 CBZ54112.1 - 2.4e-24 85.7 1.2 4e-24 84.9 0.8 1.3 1 0 0 1 1 1 1 14-3-3 protein M16C_assoc PF08367.6 CBZ54113.1 - 1.4e-46 158.4 0.0 2e-46 157.8 0.0 1.3 1 0 0 1 1 1 1 Peptidase M16C associated Peptidase_M16_C PF05193.16 CBZ54113.1 - 7.8e-21 74.5 0.0 5.7e-17 61.9 0.0 3.0 3 0 0 3 3 3 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 CBZ54113.1 - 2.3e-06 27.4 0.2 8.1e-06 25.6 0.0 2.0 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Cupin_2 PF07883.6 CBZ54119.1 - 0.014 14.9 0.0 0.031 13.7 0.0 1.5 1 0 0 1 1 1 0 Cupin domain zf-Tim10_DDP PF02953.10 CBZ54120.1 - 5.4e-11 41.6 2.4 7.1e-11 41.2 1.7 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger MAGE_N PF12440.3 CBZ54121.1 - 3.4 8.0 34.7 2.8 8.2 11.6 2.6 2 0 0 2 2 2 0 Melanoma associated antigen family N terminal Pro_isomerase PF00160.16 CBZ54122.1 - 3.6e-25 88.9 0.0 3.8e-12 46.6 0.0 2.4 2 0 0 2 2 2 2 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.17 CBZ54122.1 - 1.9e-13 49.7 0.0 3.5e-13 48.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBZ54122.1 - 2.1e-09 37.2 0.0 3.9e-09 36.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBZ54122.1 - 7e-05 22.6 0.0 0.00014 21.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Memo PF01875.12 CBZ54123.1 - 1.1e-53 181.8 0.0 5.9e-25 87.6 0.0 3.0 1 1 2 3 3 3 3 Memo-like protein Tim44 PF04280.10 CBZ54124.1 - 6.3e-18 65.1 0.0 1e-16 61.2 0.0 2.6 2 1 0 2 2 2 1 Tim44-like domain HATPase_c_3 PF13589.1 CBZ54124.1 - 0.045 13.4 0.5 0.095 12.3 0.4 1.5 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Macoilin PF09726.4 CBZ54124.1 - 0.62 8.2 20.9 0.91 7.7 14.5 1.1 1 0 0 1 1 1 0 Transmembrane protein DUF2450 PF10475.4 CBZ54125.1 - 0.0002 20.4 4.2 0.0012 17.8 2.5 2.2 2 0 0 2 2 2 1 Protein of unknown function N-terminal domain (DUF2450) DUF945 PF06097.6 CBZ54125.1 - 0.65 8.7 0.3 1 8.0 0.2 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF945) Kinase-like PF14531.1 CBZ54126.1 - 9.3e-13 47.7 0.0 1.4e-12 47.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase PF00069.20 CBZ54126.1 - 7.4e-09 35.1 0.0 4e-08 32.7 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain APH PF01636.18 CBZ54126.1 - 0.0089 15.7 0.1 0.0089 15.7 0.0 3.0 2 2 1 3 3 3 1 Phosphotransferase enzyme family EF-hand_4 PF12763.2 CBZ54127.1 - 6e-23 80.5 0.0 1e-12 47.7 0.0 2.4 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.27 CBZ54127.1 - 2.5e-09 35.7 0.0 0.0012 17.9 0.0 3.5 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.1 CBZ54127.1 - 8.3e-09 35.4 0.0 6e-07 29.4 0.0 2.7 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.1 CBZ54127.1 - 3.1e-05 23.4 0.0 0.41 10.6 0.0 3.6 3 0 0 3 3 3 1 EF-hand domain EF-hand_8 PF13833.1 CBZ54127.1 - 0.03 13.9 0.0 0.37 10.4 0.0 2.3 2 0 0 2 2 2 0 EF-hand domain pair EF-hand_5 PF13202.1 CBZ54127.1 - 0.042 13.2 0.1 0.64 9.4 0.0 2.7 3 0 0 3 3 3 0 EF hand Glycos_transf_1 PF00534.15 CBZ54128.1 - 0.17 11.2 0.0 0.47 9.8 0.0 1.8 2 0 0 2 2 2 0 Glycosyl transferases group 1 E1-E2_ATPase PF00122.15 CBZ54129.1 - 0.00093 18.2 0.1 0.0084 15.1 0.0 2.3 2 0 0 2 2 2 1 E1-E2 ATPase DNA_methylase PF00145.12 CBZ54130.1 - 1.1e-23 83.9 0.0 7.9e-14 51.5 0.0 3.2 3 0 0 3 3 3 3 C-5 cytosine-specific DNA methylase EB1 PF03271.12 CBZ54131.1 - 1.4e-08 34.6 0.0 2.5e-08 33.8 0.0 1.5 1 0 0 1 1 1 1 EB1-like C-terminal motif KAR9 PF08580.5 CBZ54131.1 - 0.19 9.9 1.3 0.23 9.6 0.9 1.1 1 0 0 1 1 1 0 Yeast cortical protein KAR9 ATP-synt_B PF00430.13 CBZ54133.1 - 0.45 10.3 4.2 1.2 8.9 0.2 2.2 2 0 0 2 2 2 0 ATP synthase B/B' CF(0) Foie-gras_1 PF11817.3 CBZ54134.1 - 0.078 12.4 0.6 0.21 11.0 0.4 1.7 1 0 0 1 1 1 0 Foie gras liver health family 1 TPR_2 PF07719.12 CBZ54134.1 - 0.42 10.6 2.0 8.3 6.6 0.3 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat KicB PF03882.9 CBZ54134.1 - 1.3 7.5 0.0 2.1 6.8 0.0 1.2 1 0 0 1 1 1 0 KicB killing factor Baculo_VP91_N PF08475.5 CBZ54134.1 - 4.3 6.6 0.0 7.4 5.8 0.0 1.2 1 0 0 1 1 1 0 Viral capsid protein 91 N-terminal Ribosomal_L34e PF01199.13 CBZ54135.1 - 1e-34 118.6 4.6 1e-34 118.6 3.2 1.9 2 0 0 2 2 2 1 Ribosomal protein L34e Cytochrome_C7 PF14522.1 CBZ54135.1 - 0.031 13.9 2.0 0.087 12.4 1.4 1.9 1 1 0 1 1 1 0 Cytochrome c7 EndIII_4Fe-2S PF10576.4 CBZ54135.1 - 5.7 7.2 7.4 2.1 8.6 0.7 2.3 2 0 0 2 2 2 0 Iron-sulfur binding domain of endonuclease III Aa_trans PF01490.13 CBZ54137.1 - 1.3e-52 178.7 32.3 1.5e-52 178.5 22.4 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Aa_trans PF01490.13 CBZ54138.1 - 1.7e-57 194.7 29.6 2.1e-57 194.4 20.5 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Med26 PF08711.6 CBZ54139.1 - 2e-07 30.4 0.1 3.3e-07 29.6 0.1 1.4 1 0 0 1 1 1 1 TFIIS helical bundle-like domain BLVR PF06375.6 CBZ54139.1 - 0.014 15.2 14.3 0.043 13.6 9.9 1.9 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) RNase_H2-Ydr279 PF09468.5 CBZ54139.1 - 0.57 9.3 8.9 2.3 7.3 6.5 1.7 2 0 0 2 2 2 0 Ydr279p protein family (RNase H2 complex component) RNA_polI_A34 PF08208.6 CBZ54139.1 - 0.61 9.7 16.2 1.3 8.6 11.2 1.5 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Med19 PF10278.4 CBZ54139.1 - 5.7 6.5 17.2 15 5.1 11.9 1.7 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 DCP2 PF05026.8 CBZ54140.1 - 2e-22 78.8 1.1 3.3e-22 78.1 0.7 1.3 1 0 0 1 1 1 1 Dcp2, box A domain NUDIX PF00293.23 CBZ54140.1 - 5.2e-12 45.5 0.0 1.1e-11 44.5 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain Aa_trans PF01490.13 CBZ54141.1 - 1.7e-43 148.6 22.1 2e-43 148.4 15.3 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Sarcolipin PF05366.6 CBZ54141.1 - 0.13 11.6 1.3 0.62 9.5 0.0 2.6 2 0 0 2 2 2 0 Sarcolipin LYTB PF02401.13 CBZ54142.1 - 4.1e-103 344.1 0.9 5.5e-103 343.7 0.7 1.2 1 0 0 1 1 1 1 LytB protein CoA_binding_2 PF13380.1 CBZ54142.1 - 0.086 13.0 5.7 5.2 7.2 0.1 4.0 2 2 2 4 4 4 0 CoA binding domain TYW3 PF02676.9 CBZ54144.1 - 4.3e-23 81.5 0.8 9e-13 47.8 0.0 3.0 4 0 0 4 4 4 2 Methyltransferase TYW3 Peptidase_S15 PF02129.13 CBZ54147.1 - 9.4e-44 149.8 0.3 9.3e-43 146.5 0.1 2.1 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.5 CBZ54147.1 - 8.9e-13 48.6 0.0 4.1e-09 36.6 0.0 2.3 2 0 0 2 2 2 2 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Abhydrolase_5 PF12695.2 CBZ54147.1 - 2e-07 30.8 0.2 0.00037 20.2 0.1 2.5 2 0 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CBZ54147.1 - 3.8e-06 26.9 0.7 7.5e-06 25.9 0.5 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 CBZ54147.1 - 0.0064 16.3 0.1 0.025 14.4 0.0 2.0 2 0 0 2 2 2 1 Putative lysophospholipase PEP-utilisers_N PF05524.8 CBZ54147.1 - 0.009 15.8 0.2 0.02 14.6 0.1 1.5 1 0 0 1 1 1 1 PEP-utilising enzyme, N-terminal Peptidase_S9 PF00326.16 CBZ54147.1 - 0.012 14.8 2.0 0.021 14.0 1.4 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Sugarporin_N PF11471.3 CBZ54147.1 - 0.6 9.7 3.1 1.3 8.6 2.1 1.5 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension Ribosomal_L3 PF00297.17 CBZ54148.1 - 2.5e-110 367.9 4.9 3e-110 367.7 3.4 1.1 1 0 0 1 1 1 1 Ribosomal protein L3 Patched PF02460.13 CBZ54149.1 - 5.6e-12 44.4 5.2 3.6e-05 21.9 4.0 3.0 3 0 0 3 3 3 2 Patched family Sterol-sensing PF12349.3 CBZ54149.1 - 2.2e-06 27.1 1.9 2.2e-06 27.1 1.3 1.8 2 0 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation Macoilin PF09726.4 CBZ54151.1 - 0.029 12.6 3.3 0.044 12.0 2.3 1.2 1 0 0 1 1 1 0 Transmembrane protein MIP-T3 PF10243.4 CBZ54152.1 - 0.03 12.8 65.4 0.036 12.5 45.3 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DUF1510 PF07423.6 CBZ54152.1 - 1.3 8.3 40.5 1.9 7.8 28.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DUF262 PF03235.9 CBZ54152.1 - 3.8 7.4 16.7 4.3 7.2 11.6 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF262 SprA-related PF12118.3 CBZ54152.1 - 3.8 6.7 30.4 4.9 6.3 21.1 1.2 1 0 0 1 1 1 0 SprA-related family DUF2413 PF10310.4 CBZ54152.1 - 6 5.5 36.6 6.5 5.4 25.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) Hist_deacetyl PF00850.14 CBZ54154.1 - 2.7e-77 260.1 0.2 4e-77 259.5 0.1 1.2 1 0 0 1 1 1 1 Histone deacetylase domain PRCC PF10253.4 CBZ54156.1 - 1.1e-26 94.6 0.7 1.1e-26 94.6 0.5 2.1 2 0 0 2 2 2 1 Mitotic checkpoint regulator, MAD2B-interacting RIO1 PF01163.17 CBZ54157.1 - 6.2e-45 152.8 0.4 1.4e-44 151.7 0.3 1.5 1 0 0 1 1 1 1 RIO1 family Rio2_N PF09202.6 CBZ54157.1 - 2.9e-33 113.7 1.1 1.9e-32 111.1 0.3 2.3 2 0 0 2 2 2 1 Rio2, N-terminal Kdo PF06293.9 CBZ54157.1 - 2.4e-07 30.0 0.4 7.7e-06 25.1 0.3 2.3 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CBZ54157.1 - 2.7e-07 30.5 7.8 7.5e-05 22.5 0.8 2.8 1 1 1 2 2 2 2 Phosphotransferase enzyme family WaaY PF06176.6 CBZ54157.1 - 0.062 12.5 0.1 0.092 11.9 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) TFIIF_alpha PF05793.7 CBZ54157.1 - 1.2 7.3 33.5 1.6 6.9 23.2 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Glutaredoxin PF00462.19 CBZ54158.1 - 2.6e-14 52.9 0.2 5.3e-14 51.9 0.2 1.6 1 0 0 1 1 1 1 Glutaredoxin DUF836 PF05768.9 CBZ54158.1 - 0.071 13.3 0.1 0.18 12.0 0.0 1.7 2 0 0 2 2 2 0 Glutaredoxin-like domain (DUF836) Redoxin PF08534.5 CBZ54158.1 - 0.089 12.3 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Redoxin PUA PF01472.15 CBZ54159.1 - 0.12 12.0 0.3 0.29 10.8 0.2 1.5 1 0 0 1 1 1 0 PUA domain Glutaredoxin PF00462.19 CBZ54161.1 - 2.2e-05 24.3 0.1 3.6e-05 23.6 0.1 1.4 1 0 0 1 1 1 1 Glutaredoxin Calmodulin_bind PF07887.6 CBZ54161.1 - 0.068 12.2 0.2 0.072 12.1 0.2 1.1 1 0 0 1 1 1 0 Calmodulin binding protein-like AA_kinase PF00696.23 CBZ54162.1 - 3.4e-49 167.5 0.0 5.1e-49 167.0 0.0 1.3 1 0 0 1 1 1 1 Amino acid kinase family Peptidase_S49 PF01343.13 CBZ54162.1 - 0.0027 17.4 0.0 0.21 11.3 0.0 2.3 2 0 0 2 2 2 1 Peptidase family S49 ACT PF01842.20 CBZ54162.1 - 0.0042 16.5 0.3 0.12 11.9 0.0 2.9 2 0 0 2 2 2 1 ACT domain PCIF1_WW PF12237.3 CBZ54163.1 - 8.1e-50 168.5 0.0 1.4e-49 167.7 0.0 1.3 1 0 0 1 1 1 1 Phosphorylated CTD interacting factor 1 WW domain HATPase_c PF02518.21 CBZ54165.1 - 7.2e-12 45.0 0.1 5.7e-11 42.1 0.0 2.1 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SIR2 PF02146.12 CBZ54167.1 - 5.3e-46 156.5 0.0 7e-46 156.1 0.0 1.2 1 0 0 1 1 1 1 Sir2 family TPP_enzyme_M PF00205.17 CBZ54167.1 - 3.6e-06 26.7 0.0 0.00018 21.2 0.0 2.2 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain DUF2688 PF10892.3 CBZ54167.1 - 0.044 13.4 0.1 0.08 12.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2688) Pkinase PF00069.20 CBZ54168.1 - 3.2e-16 59.2 0.0 5.3e-16 58.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.1 CBZ54168.1 - 1.1e-10 41.0 0.0 3.3e-10 39.4 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Pkinase_Tyr PF07714.12 CBZ54168.1 - 0.0022 17.1 0.0 0.0035 16.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase eIF3_subunit PF08597.5 CBZ54171.1 - 1.8e-16 60.4 13.2 2.2e-16 60.1 9.1 1.1 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit DUF3752 PF12572.3 CBZ54171.1 - 3.1 7.8 11.5 0.26 11.4 2.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3752) DNA_pol3_a_NII PF11490.3 CBZ54171.1 - 4.3 6.9 8.5 10 5.7 0.1 2.4 2 0 0 2 2 2 0 DNA polymerase III polC-type N-terminus II Seryl_tRNA_N PF02403.17 CBZ54171.1 - 4.4 7.3 11.6 1.1 9.2 0.9 2.7 2 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain UPF0542 PF15086.1 CBZ54171.1 - 4.7 6.9 7.1 9.5 6.0 0.5 2.5 2 0 0 2 2 2 0 Uncharacterised protein family UPF0542 Ribosomal_S17 PF00366.15 CBZ54172.1 - 7.7e-28 96.3 0.9 1.2e-27 95.7 0.6 1.3 1 0 0 1 1 1 1 Ribosomal protein S17 PFK PF00365.15 CBZ54173.1 - 4.9e-28 97.8 5.7 4e-23 81.7 0.1 2.7 3 1 0 3 3 3 2 Phosphofructokinase Pentapeptide PF00805.17 CBZ54175.1 - 1.3e-06 27.4 30.7 44 3.4 0.0 14.2 7 3 4 16 16 16 11 Pentapeptide repeats (8 copies) UCH PF00443.24 CBZ54176.1 - 2.1e-41 141.8 0.0 5.7e-41 140.4 0.0 1.7 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CBZ54176.1 - 1.5e-17 63.9 0.2 1.5e-10 41.0 0.0 3.5 4 0 0 4 4 4 3 Ubiquitin carboxyl-terminal hydrolase Ycf1 PF05758.7 CBZ54176.1 - 0.13 9.9 5.7 0.19 9.3 3.9 1.2 1 0 0 1 1 1 0 Ycf1 Trypsin_2 PF13365.1 CBZ54177.1 - 7.6e-11 42.0 0.3 2.6e-06 27.4 0.0 3.3 2 1 0 2 2 2 2 Trypsin-like peptidase domain hDGE_amylase PF14701.1 CBZ54178.1 - 6.6e-124 414.0 0.0 3e-99 332.7 0.0 2.0 2 0 0 2 2 2 2 glucanotransferase domain of human glycogen debranching enzyme GDE_C PF06202.9 CBZ54178.1 - 1e-110 370.0 0.0 1.8e-110 369.1 0.0 1.4 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase hGDE_central PF14702.1 CBZ54178.1 - 4.8e-37 127.5 0.0 6.9e-37 127.0 0.0 1.2 1 0 0 1 1 1 1 central domain of human glycogen debranching enzyme Alpha-amylase PF00128.19 CBZ54178.1 - 0.36 10.1 0.0 4 6.7 0.0 2.3 3 0 0 3 3 3 0 Alpha amylase, catalytic domain ORC3_N PF07034.6 CBZ54180.1 - 0.0011 18.0 9.8 0.0025 16.8 2.7 3.1 3 0 0 3 3 3 2 Origin recognition complex (ORC) subunit 3 N-terminus Tubulin PF00091.20 CBZ54181.1 - 5.3e-76 255.2 0.0 7.5e-76 254.7 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 CBZ54181.1 - 1.7e-46 157.3 0.7 1.7e-46 157.3 0.5 1.6 2 0 0 2 2 2 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 CBZ54181.1 - 2.1e-07 30.9 0.0 3.9e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_2 PF13809.1 CBZ54181.1 - 0.11 11.3 0.0 0.19 10.6 0.0 1.3 1 0 0 1 1 1 0 Tubulin like SAG PF04092.8 CBZ54182.1 - 0.079 13.3 0.0 0.11 12.9 0.0 1.3 1 0 0 1 1 1 0 SRS domain RabGAP-TBC PF00566.13 CBZ54183.1 - 3.4e-36 124.7 3.1 1.1e-22 80.6 0.0 2.2 1 1 1 2 2 2 2 Rab-GTPase-TBC domain DUF2217 PF10265.4 CBZ54183.1 - 0.08 11.6 20.4 0.047 12.4 5.5 2.5 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2217) Cupin_8 PF13621.1 CBZ54184.1 - 2.7e-40 138.4 0.0 1.1e-39 136.4 0.0 2.1 2 1 0 2 2 2 1 Cupin-like domain Cupin_4 PF08007.7 CBZ54184.1 - 0.09 12.0 0.0 0.09 12.0 0.0 2.4 3 0 0 3 3 3 0 Cupin superfamily protein JmjC PF02373.17 CBZ54184.1 - 0.17 12.1 0.0 0.47 10.7 0.0 1.7 2 0 0 2 2 2 0 JmjC domain, hydroxylase Fmp27_WPPW PF10359.4 CBZ54184.1 - 3.6 5.8 4.7 5.6 5.2 3.3 1.2 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain HSP70 PF00012.15 CBZ54185.1 - 5.6e-59 199.6 26.7 3.1e-48 164.1 0.2 4.2 4 0 0 4 4 4 3 Hsp70 protein MreB_Mbl PF06723.8 CBZ54185.1 - 3.7e-06 25.7 1.1 9.2e-06 24.4 0.3 2.0 2 1 0 2 2 2 1 MreB/Mbl protein SET PF00856.23 CBZ54187.1 - 1e-18 68.1 0.2 1e-18 68.1 0.2 3.8 3 1 0 3 3 3 1 SET domain Bromodomain PF00439.20 CBZ54187.1 - 2.2e-14 53.1 0.0 3.6e-14 52.4 0.0 1.3 1 0 0 1 1 1 1 Bromodomain PHD PF00628.24 CBZ54187.1 - 8.7e-06 25.3 74.3 0.00045 19.8 2.9 8.0 7 0 0 7 7 7 4 PHD-finger FYRN PF05964.9 CBZ54187.1 - 2 7.9 0.0 5 6.6 0.0 1.6 1 0 0 1 1 1 0 F/Y-rich N-terminus Phage_head_chap PF11113.3 CBZ54187.1 - 9.2 6.2 0.0 17 5.3 0.0 1.4 1 0 0 1 1 1 0 Head assembly gene product GSH_synth_ATP PF03917.12 CBZ54188.1 - 4.3e-48 163.7 0.5 1.4e-13 50.1 0.0 6.7 7 0 0 7 7 7 6 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.10 CBZ54188.1 - 1.3e-16 60.5 0.0 1.7e-11 44.0 0.0 2.5 2 0 0 2 2 2 2 Eukaryotic glutathione synthase ABC_tran PF00005.22 CBZ54189.1 - 3.9e-39 134.0 0.0 1.9e-19 70.3 0.0 4.3 3 2 0 3 3 3 3 ABC transporter AAA_21 PF13304.1 CBZ54189.1 - 3.5e-22 79.6 0.0 5.3e-05 23.3 0.0 4.4 4 0 0 4 4 4 4 AAA domain SMC_N PF02463.14 CBZ54189.1 - 7.1e-10 38.4 0.3 0.058 12.6 0.0 4.2 4 1 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 CBZ54189.1 - 1.5e-08 35.4 1.7 0.00016 22.4 0.1 3.5 2 2 0 2 2 2 2 AAA domain AAA_23 PF13476.1 CBZ54189.1 - 2.4e-07 31.3 10.1 0.0046 17.2 0.5 3.7 3 1 0 3 3 3 2 AAA domain AAA_29 PF13555.1 CBZ54189.1 - 3.1e-07 29.8 0.5 0.0021 17.5 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_25 PF13481.1 CBZ54189.1 - 3.2e-07 29.9 0.5 0.0024 17.2 0.0 3.1 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 CBZ54189.1 - 4.9e-06 25.8 0.1 0.069 12.3 0.1 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_15 PF13175.1 CBZ54189.1 - 5.4e-06 25.7 0.0 1.2 8.0 0.0 3.8 4 0 0 4 4 4 2 AAA ATPase domain AAA_22 PF13401.1 CBZ54189.1 - 6e-06 26.4 0.4 0.22 11.6 0.0 3.5 4 0 0 4 4 3 2 AAA domain SbcCD_C PF13558.1 CBZ54189.1 - 1.2e-05 25.0 0.1 0.0025 17.6 0.0 3.4 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit MobB PF03205.9 CBZ54189.1 - 1.5e-05 24.7 0.0 0.065 12.9 0.0 2.5 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B NACHT PF05729.7 CBZ54189.1 - 1.7e-05 24.5 0.0 0.15 11.7 0.0 2.6 2 0 0 2 2 2 2 NACHT domain AAA_30 PF13604.1 CBZ54189.1 - 1.8e-05 24.4 0.2 0.32 10.5 0.1 3.0 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 CBZ54189.1 - 3.9e-05 23.7 11.9 0.022 14.7 0.1 3.8 4 0 0 4 4 3 2 AAA ATPase domain AAA_19 PF13245.1 CBZ54189.1 - 6.9e-05 22.5 2.1 0.24 11.1 0.1 3.0 2 0 0 2 2 2 2 Part of AAA domain AAA_28 PF13521.1 CBZ54189.1 - 9.1e-05 22.4 2.9 0.078 12.9 0.0 3.2 3 0 0 3 3 2 2 AAA domain AAA_10 PF12846.2 CBZ54189.1 - 0.00016 21.2 0.8 0.017 14.5 0.1 2.9 3 0 0 3 3 3 1 AAA-like domain Miro PF08477.8 CBZ54189.1 - 0.00025 21.5 0.0 0.44 11.0 0.0 2.5 2 0 0 2 2 2 1 Miro-like protein AAA_18 PF13238.1 CBZ54189.1 - 0.00029 21.1 2.2 0.074 13.3 0.2 3.4 3 1 0 3 3 2 1 AAA domain AAA PF00004.24 CBZ54189.1 - 0.00034 20.8 0.0 2.5 8.2 0.0 3.3 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 CBZ54189.1 - 0.00043 20.1 0.1 0.25 11.2 0.0 2.8 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 CBZ54189.1 - 0.00059 18.9 0.6 0.41 9.7 0.1 2.6 2 0 0 2 2 2 2 Zeta toxin MMR_HSR1 PF01926.18 CBZ54189.1 - 0.00073 19.4 0.2 0.33 10.9 0.1 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_5 PF07728.9 CBZ54189.1 - 0.0016 18.1 0.3 1.5 8.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) UPF0079 PF02367.12 CBZ54189.1 - 0.002 17.7 0.2 0.21 11.2 0.0 2.4 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_24 PF13479.1 CBZ54189.1 - 0.0032 17.0 0.1 0.64 9.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_13 PF13166.1 CBZ54189.1 - 0.0037 15.7 0.3 2.2 6.6 0.0 2.9 3 0 0 3 3 3 1 AAA domain cobW PF02492.14 CBZ54189.1 - 0.0057 16.1 0.1 2.5 7.5 0.0 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain Dynamin_N PF00350.18 CBZ54189.1 - 0.011 15.5 0.1 2.2 8.0 0.1 2.9 2 1 0 2 2 2 0 Dynamin family AAA_14 PF13173.1 CBZ54189.1 - 0.012 15.4 0.1 1.3 8.8 0.0 2.8 3 0 0 3 3 2 0 AAA domain PduV-EutP PF10662.4 CBZ54189.1 - 0.019 14.4 0.0 2.6 7.5 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Arch_ATPase PF01637.13 CBZ54189.1 - 0.019 14.6 0.1 3.6 7.2 0.0 2.5 2 0 0 2 2 2 0 Archaeal ATPase SRP54 PF00448.17 CBZ54189.1 - 0.031 13.7 0.1 6.6 6.1 0.0 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain NTPase_1 PF03266.10 CBZ54189.1 - 0.034 13.8 0.1 0.76 9.4 0.0 2.4 2 0 0 2 2 2 0 NTPase RNA_helicase PF00910.17 CBZ54189.1 - 0.04 14.0 0.0 3.2 7.9 0.0 2.4 2 0 0 2 2 2 0 RNA helicase TrkA_C PF02080.16 CBZ54189.1 - 0.091 12.3 0.0 0.23 11.1 0.0 1.6 1 0 0 1 1 1 0 TrkA-C domain Mg_chelatase PF01078.16 CBZ54189.1 - 0.094 11.8 0.4 15 4.6 0.0 3.0 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.12 CBZ54189.1 - 0.12 11.7 0.0 8.9 5.6 0.0 2.3 2 0 0 2 2 2 0 IstB-like ATP binding protein KAP_NTPase PF07693.9 CBZ54189.1 - 0.14 11.1 0.0 10 4.9 0.0 2.7 3 0 0 3 3 2 0 KAP family P-loop domain Pox_A32 PF04665.7 CBZ54189.1 - 0.14 11.4 0.1 11 5.2 0.0 2.4 2 0 0 2 2 2 0 Poxvirus A32 protein MutS_V PF00488.16 CBZ54189.1 - 0.2 11.0 0.0 2.5 7.4 0.0 2.2 2 0 0 2 2 2 0 MutS domain V ATP_bind_1 PF03029.12 CBZ54189.1 - 0.59 9.6 0.0 8.6 5.8 0.0 2.1 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein DUF87 PF01935.12 CBZ54189.1 - 0.93 9.2 2.8 2.6 7.7 0.1 2.5 3 0 0 3 3 2 0 Domain of unknown function DUF87 zf-C3HC4_2 PF13923.1 CBZ54190.1 - 7.4e-07 29.0 12.8 1.2e-06 28.4 8.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CBZ54190.1 - 4.1e-06 26.3 10.9 6.8e-06 25.6 7.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CBZ54190.1 - 4.3e-06 26.4 11.4 7e-06 25.7 7.9 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 CBZ54190.1 - 0.00086 18.9 14.5 0.0013 18.3 10.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBZ54190.1 - 0.0016 18.0 10.9 0.0025 17.4 7.6 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 CBZ54190.1 - 0.011 15.5 11.5 0.019 14.8 7.9 1.4 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 CBZ54190.1 - 0.016 14.8 6.9 0.037 13.7 4.8 1.6 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_6 PF14835.1 CBZ54190.1 - 0.075 12.8 10.0 0.15 11.8 6.9 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-Nse PF11789.3 CBZ54190.1 - 0.12 11.9 7.7 0.21 11.1 5.3 1.3 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit RRN3 PF05327.6 CBZ54190.1 - 0.34 8.9 1.0 0.48 8.4 0.7 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Nop14 PF04147.7 CBZ54190.1 - 0.47 8.3 9.1 0.65 7.8 6.3 1.1 1 0 0 1 1 1 0 Nop14-like family zf-RING_4 PF14570.1 CBZ54190.1 - 0.64 9.6 10.5 1.3 8.7 7.3 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain CDC45 PF02724.9 CBZ54190.1 - 0.66 7.9 14.9 0.98 7.3 10.3 1.1 1 0 0 1 1 1 0 CDC45-like protein zf-rbx1 PF12678.2 CBZ54190.1 - 1.3 9.2 6.0 2.3 8.3 4.2 1.4 1 0 0 1 1 1 0 RING-H2 zinc finger PDEase_I PF00233.14 CBZ54191.1 - 7.5e-39 133.8 0.1 1.8e-37 129.3 0.0 2.1 2 0 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase DUF1426 PF07234.6 CBZ54191.1 - 0.58 9.9 0.0 1.8 8.3 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1426) CoA_binding_3 PF13727.1 CBZ54191.1 - 0.81 9.4 1.0 1.5 8.5 0.7 1.4 1 0 0 1 1 1 0 CoA-binding domain EIAV_GP90 PF00971.13 CBZ54191.1 - 4.1 5.7 0.0 6.6 5.0 0.0 1.1 1 0 0 1 1 1 0 EIAV coat protein, gp90 zf-RING_2 PF13639.1 CBZ54192.1 - 3.2e-14 52.4 4.0 8e-14 51.1 2.8 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 CBZ54192.1 - 2.7e-08 33.6 3.8 6.4e-08 32.5 2.7 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 CBZ54192.1 - 7.1e-08 32.4 2.4 1.4e-07 31.4 1.7 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 CBZ54192.1 - 4.9e-06 26.1 2.2 9.6e-06 25.1 1.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBZ54192.1 - 2.1e-05 24.1 2.0 5.3e-05 22.8 1.4 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 CBZ54192.1 - 8.7e-05 22.1 4.5 0.00017 21.1 3.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_1 PF14446.1 CBZ54192.1 - 0.0003 20.4 0.7 0.0003 20.4 0.5 2.3 2 0 0 2 2 2 1 Prokaryotic RING finger family 1 zf-Apc11 PF12861.2 CBZ54192.1 - 0.0036 17.1 2.1 0.0097 15.7 1.5 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger PHD PF00628.24 CBZ54192.1 - 0.071 12.8 2.4 0.16 11.6 1.7 1.7 1 0 0 1 1 1 0 PHD-finger zf-DHHC PF01529.15 CBZ54192.1 - 2.8 7.3 8.4 0.14 11.5 0.5 2.1 1 1 1 2 2 2 0 DHHC palmitoyltransferase EI24 PF07264.6 CBZ54192.1 - 7.2 5.9 14.5 0.079 12.3 4.1 1.8 2 0 0 2 2 2 0 Etoposide-induced protein 2.4 (EI24) Aconitase PF00330.15 CBZ54193.1 - 9.3e-145 482.6 0.0 1.2e-144 482.3 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 CBZ54193.1 - 6.7e-43 145.9 0.0 1.1e-42 145.1 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain Translin PF01997.11 CBZ54194.1 - 2.5e-33 115.3 0.6 2.9e-33 115.1 0.4 1.0 1 0 0 1 1 1 1 Translin family DUF3522 PF12036.3 CBZ54195.1 - 5.8e-20 71.8 6.0 1.1e-19 70.9 4.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3522) TrbC PF04956.8 CBZ54196.1 - 0.042 13.8 0.4 0.061 13.3 0.2 1.2 1 0 0 1 1 1 0 TrbC/VIRB2 family MscS_TM PF12794.2 CBZ54196.1 - 0.11 11.1 0.2 0.13 10.8 0.1 1.1 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 DUF3357 PF11837.3 CBZ54196.1 - 0.18 11.6 3.8 0.34 10.7 0.1 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF3357) SNase PF00565.12 CBZ54197.1 - 5.5e-21 74.8 0.0 4.6e-14 52.5 0.0 2.3 2 0 0 2 2 2 2 Staphylococcal nuclease homologue Toxin_29 PF08116.6 CBZ54200.1 - 0.91 9.3 3.7 2 8.2 2.6 1.5 1 0 0 1 1 1 0 PhTx neurotoxin family Urb2 PF10441.4 CBZ54201.1 - 0.069 12.7 0.1 0.17 11.4 0.0 1.6 1 0 0 1 1 1 0 Urb2/Npa2 family MSP1_C PF07462.6 CBZ54201.1 - 4.7 5.4 3.6 11 4.3 2.5 1.5 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Yippee-Mis18 PF03226.9 CBZ54202.1 - 7.6e-19 67.5 1.2 9.4e-19 67.2 0.8 1.1 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly zinc_ribbon_6 PF14599.1 CBZ54202.1 - 0.099 12.4 0.1 0.099 12.4 0.1 2.1 2 0 0 2 2 2 0 Zinc-ribbon GFA PF04828.9 CBZ54202.1 - 1.9 8.4 6.8 19 5.3 4.7 2.2 1 1 0 1 1 1 0 Glutathione-dependent formaldehyde-activating enzyme CEP76-C2 PF15627.1 CBZ54204.1 - 1.3e-05 24.7 0.1 0.00022 20.7 0.0 2.2 1 1 1 2 2 2 1 CEP76 C2 domain Phage_rep_org_N PF09681.5 CBZ54204.1 - 0.024 14.2 0.0 0.045 13.3 0.0 1.4 1 0 0 1 1 1 0 N-terminal phage replisome organiser (Phage_rep_org_N) SNARE PF05739.14 CBZ54205.1 - 1e-13 50.7 3.0 1e-13 50.7 2.1 2.2 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.20 CBZ54205.1 - 2.7e-11 43.5 0.9 2.7e-11 43.5 0.6 2.2 2 0 0 2 2 2 1 Syntaxin RmuC PF02646.11 CBZ54205.1 - 0.02 13.7 6.7 0.62 8.8 0.6 2.3 2 1 0 2 2 2 0 RmuC family Tup_N PF08581.5 CBZ54205.1 - 0.033 14.3 1.2 0.033 14.3 0.8 2.8 2 2 0 2 2 2 0 Tup N-terminal HSBP1 PF06825.7 CBZ54205.1 - 0.034 13.7 1.9 0.19 11.3 0.4 2.3 2 0 0 2 2 2 0 Heat shock factor binding protein 1 Vac_Fusion PF02346.11 CBZ54205.1 - 0.039 13.3 2.4 0.19 11.1 0.1 2.6 3 0 0 3 3 3 0 Chordopoxvirus fusion protein DUF310 PF03750.8 CBZ54205.1 - 0.082 13.0 3.7 0.15 12.2 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF310) Syntaxin-6_N PF09177.6 CBZ54205.1 - 0.17 12.2 4.8 7.8 6.9 0.5 2.5 2 1 0 2 2 2 0 Syntaxin 6, N-terminal SF-assemblin PF06705.6 CBZ54205.1 - 0.22 10.6 7.5 0.12 11.4 0.7 2.3 2 1 0 2 2 2 0 SF-assemblin/beta giardin DUF2408 PF10303.4 CBZ54205.1 - 0.96 9.5 5.0 1.8 8.7 1.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) zf-C4H2 PF10146.4 CBZ54205.1 - 1.4 8.9 4.7 1.5 8.8 0.3 2.1 2 0 0 2 2 2 0 Zinc finger-containing protein Rho_N PF07498.7 CBZ54205.1 - 1.4 8.7 6.4 0.17 11.6 1.0 2.0 2 0 0 2 2 2 0 Rho termination factor, N-terminal domain Baculo_PEP_C PF04513.7 CBZ54205.1 - 2.1 8.1 7.6 1.6 8.5 0.6 2.9 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus CorA PF01544.13 CBZ54205.1 - 5.6 5.8 8.7 0.79 8.6 0.8 2.1 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein zf-CCCH PF00642.19 CBZ54209.1 - 8.5e-09 34.8 2.9 8.5e-09 34.8 2.0 1.9 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-RING_5 PF14634.1 CBZ54209.1 - 5.5e-07 29.2 9.2 9.8e-07 28.4 6.4 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 CBZ54209.1 - 7.5e-06 25.5 5.7 1.4e-05 24.6 4.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CBZ54209.1 - 1.2e-05 25.1 9.9 2.5e-05 24.2 6.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CBZ54209.1 - 2.3e-05 24.1 8.2 4e-05 23.3 5.7 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.1 CBZ54209.1 - 0.00077 19.1 2.1 0.0021 17.7 1.4 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.20 CBZ54209.1 - 0.011 15.3 9.0 0.036 13.7 6.2 1.9 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 CBZ54209.1 - 0.14 12.0 9.7 0.065 13.1 3.6 2.5 1 1 2 3 3 3 0 zinc finger of C3HC4-type, RING zf-P11 PF03854.9 CBZ54209.1 - 4.6 6.8 6.6 9 5.8 4.6 1.4 1 0 0 1 1 1 0 P-11 zinc finger RabGAP-TBC PF00566.13 CBZ54210.1 - 3.3e-21 75.7 0.0 3.3e-21 75.7 0.0 1.4 2 0 0 2 2 2 1 Rab-GTPase-TBC domain Pkinase PF00069.20 CBZ54211.1 - 1.3e-45 155.5 0.0 1.6e-45 155.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ54211.1 - 1.2e-18 67.1 0.0 1.6e-18 66.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 CBZ54211.1 - 6.8e-05 22.0 0.1 0.00026 20.1 0.0 1.9 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CBZ54211.1 - 0.00037 20.3 0.1 0.0012 18.5 0.0 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 CBZ54211.1 - 0.00063 19.1 0.0 0.0013 18.1 0.0 1.4 1 0 0 1 1 1 1 RIO1 family Choline_kinase PF01633.15 CBZ54211.1 - 0.062 12.8 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kinase-like PF14531.1 CBZ54211.1 - 0.12 11.3 0.0 0.2 10.5 0.0 1.4 1 0 0 1 1 1 0 Kinase-like LSM PF01423.17 CBZ54212.1 - 0.00045 19.7 0.0 0.0011 18.4 0.0 1.6 1 0 0 1 1 1 1 LSM domain Sec23_trunk PF04811.10 CBZ54213.1 - 1.1e-23 83.9 0.0 5e-23 81.7 0.0 1.9 1 1 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 CBZ54213.1 - 3.2e-23 81.1 0.0 7.6e-23 79.9 0.0 1.6 1 0 0 1 1 1 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.10 CBZ54213.1 - 5.5e-11 41.8 4.5 1.1e-10 40.8 3.1 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Sec23_BS PF08033.7 CBZ54213.1 - 5e-07 30.1 0.1 4.7e-06 27.0 0.0 2.2 2 0 0 2 2 2 1 Sec23/Sec24 beta-sandwich domain Topoisom_bac PF01131.15 CBZ54216.1 - 4.6e-70 236.4 0.0 7e-52 176.6 0.0 2.1 2 0 0 2 2 2 2 DNA topoisomerase Toprim PF01751.17 CBZ54216.1 - 7.4e-16 57.9 0.0 1.2e-15 57.2 0.0 1.4 1 0 0 1 1 1 1 Toprim domain Abhydrolase_2 PF02230.11 CBZ54217.1 - 0.055 12.8 0.0 0.55 9.6 0.0 2.1 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Calsequestrin PF01216.12 CBZ54219.1 - 0.043 12.5 0.6 0.066 11.9 0.4 1.2 1 0 0 1 1 1 0 Calsequestrin SNF2_N PF00176.18 CBZ54220.1 - 6.3e-57 192.6 0.0 8e-27 93.8 0.0 3.6 3 0 0 3 3 3 3 SNF2 family N-terminal domain Helicase_C PF00271.26 CBZ54220.1 - 1.9e-12 46.8 0.0 4e-12 45.8 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-RING_2 PF13639.1 CBZ54220.1 - 1e-09 38.0 2.4 3.6e-09 36.3 1.7 2.0 1 0 0 1 1 1 1 Ring finger domain SAP PF02037.22 CBZ54220.1 - 6.6e-09 35.0 0.3 2.4e-08 33.2 0.2 2.0 1 0 0 1 1 1 1 SAP domain UBA PF00627.26 CBZ54220.1 - 9.4e-09 34.8 0.2 3.1e-08 33.2 0.2 2.0 1 0 0 1 1 1 1 UBA/TS-N domain zf-PARP PF00645.13 CBZ54220.1 - 2.3e-05 24.5 0.2 6.4e-05 23.1 0.1 1.8 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region zf-C2HC_2 PF13913.1 CBZ54220.1 - 0.00031 20.3 0.1 0.00031 20.3 0.1 2.0 2 0 0 2 2 2 1 zinc-finger of a C2HC-type zf-C3HC4 PF00097.20 CBZ54220.1 - 0.0058 16.2 1.6 0.0058 16.2 1.1 2.3 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CBZ54220.1 - 4.7 7.3 9.5 0.15 12.0 1.3 2.6 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Reticulon PF02453.12 CBZ54221.1 - 1.4e-20 73.5 4.6 1.8e-20 73.2 3.2 1.1 1 0 0 1 1 1 1 Reticulon Metallothio_2 PF01439.13 CBZ54221.1 - 0.011 16.2 0.6 0.022 15.2 0.4 1.5 1 0 0 1 1 1 0 Metallothionein p53-inducible11 PF14936.1 CBZ54221.1 - 0.28 11.1 1.6 0.4 10.6 0.2 1.8 2 0 0 2 2 2 0 Tumour protein p53-inducible protein 11 Sec20 PF03908.8 CBZ54221.1 - 8.4 6.1 9.3 0.7 9.6 2.5 2.2 2 1 0 2 2 2 0 Sec20 Peptidase_M3 PF01432.15 CBZ54222.1 - 6.3e-24 84.8 0.2 1.3e-23 83.7 0.0 1.6 2 0 0 2 2 2 1 Peptidase family M3 Peptidase_M3_N PF08439.5 CBZ54222.1 - 1.1e-06 28.6 0.2 1.3e-05 25.1 0.0 2.8 3 0 0 3 3 3 1 Oligopeptidase F EF1_GNE PF00736.14 CBZ54223.1 - 1.6e-27 95.0 1.4 1.6e-27 95.0 1.0 1.8 2 0 0 2 2 2 1 EF-1 guanine nucleotide exchange domain SmpA_OmlA PF04355.8 CBZ54223.1 - 0.15 11.6 0.0 2.2 7.9 0.0 2.3 2 0 0 2 2 2 0 SmpA / OmlA family PBP1_TM PF14812.1 CBZ54223.1 - 6.1 7.2 10.6 8 6.8 2.5 2.2 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Radical_SAM PF04055.16 CBZ54224.1 - 9.8e-14 51.8 0.0 1.9e-13 50.9 0.0 1.5 2 0 0 2 2 2 1 Radical SAM superfamily Shikimate_DH PF01488.15 CBZ54224.1 - 0.034 14.2 0.0 0.09 12.8 0.0 1.7 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Hydrolase_4 PF12146.3 CBZ54225.1 - 8.8e-10 38.3 1.6 3.8e-08 33.0 0.1 2.9 3 0 0 3 3 3 2 Putative lysophospholipase Abhydrolase_5 PF12695.2 CBZ54225.1 - 2.2e-07 30.7 0.0 9.3e-07 28.7 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family GRA6 PF05084.8 CBZ54226.1 - 0.0077 15.7 1.3 0.017 14.6 0.9 1.6 1 0 0 1 1 1 1 Granule antigen protein (GRA6) Cnl2_NKP2 PF09447.5 CBZ54226.1 - 0.092 12.4 0.1 0.23 11.1 0.1 1.6 1 0 0 1 1 1 0 Cnl2/NKP2 family protein DAGAT PF03982.8 CBZ54227.1 - 4.6e-73 245.4 0.0 6.5e-73 245.0 0.0 1.1 1 0 0 1 1 1 1 Diacylglycerol acyltransferase Acyltransferase PF01553.16 CBZ54227.1 - 0.00011 21.6 0.0 0.00026 20.4 0.0 1.6 1 0 0 1 1 1 1 Acyltransferase Mcp5_PH PF12814.2 CBZ54229.1 - 0.0052 16.6 0.0 1.1 9.2 0.0 2.7 2 0 0 2 2 2 2 Meiotic cell cortex C-terminal pleckstrin homology RRM_6 PF14259.1 CBZ54230.1 - 0.019 14.9 0.0 0.042 13.8 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) zf-CCCH PF00642.19 CBZ54231.1 - 1.3e-07 31.1 9.0 0.004 16.7 0.1 4.1 3 0 0 3 3 3 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) adh_short_C2 PF13561.1 CBZ54232.1 - 2e-29 103.0 0.5 1.2e-18 67.7 0.5 2.9 2 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 CBZ54232.1 - 2.6e-20 73.0 1.8 2.6e-19 69.7 1.3 2.0 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CBZ54232.1 - 7.3e-07 29.0 0.5 1.5e-06 27.9 0.3 1.6 1 1 0 1 1 1 1 KR domain F420_oxidored PF03807.12 CBZ54232.1 - 0.00026 21.3 0.1 0.00056 20.2 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Polysacc_synt_2 PF02719.10 CBZ54232.1 - 0.0012 17.8 0.1 0.0017 17.2 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Shikimate_DH PF01488.15 CBZ54232.1 - 0.016 15.2 0.0 0.036 14.1 0.0 1.6 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.1 CBZ54232.1 - 0.02 14.8 0.0 0.039 13.9 0.0 1.4 1 0 0 1 1 1 0 NADH(P)-binding 3HCDH_N PF02737.13 CBZ54232.1 - 0.09 12.4 0.1 0.15 11.6 0.1 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain His_biosynth PF00977.16 CBZ54232.1 - 0.11 11.7 0.0 0.18 11.0 0.0 1.3 1 0 0 1 1 1 0 Histidine biosynthesis protein AMPKBI PF04739.10 CBZ54233.1 - 0.018 14.8 0.0 0.048 13.5 0.0 1.7 1 0 0 1 1 1 0 5'-AMP-activated protein kinase beta subunit, interation domain Ribosomal_L28 PF00830.14 CBZ54234.1 - 1.5e-06 27.9 0.3 5.4e-06 26.1 0.1 2.0 2 0 0 2 2 2 1 Ribosomal L28 family DUF2053 PF09767.4 CBZ54235.1 - 7e-30 104.1 6.1 9.8e-30 103.6 4.2 1.2 1 0 0 1 1 1 1 Predicted membrane protein (DUF2053) DUF3382 PF11862.3 CBZ54235.1 - 0.028 14.3 4.5 0.33 10.8 0.0 3.0 3 1 0 3 3 3 0 Domain of unknown function (DUF3382) NfeD PF01957.13 CBZ54235.1 - 7.1 6.7 7.3 1.6 8.8 0.0 2.8 2 1 1 3 3 3 0 NfeD-like C-terminal, partner-binding DEAD PF00270.24 CBZ54237.1 - 3.3e-42 143.8 0.0 1.9e-41 141.3 0.0 2.2 2 1 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CBZ54237.1 - 1.9e-27 94.9 0.0 3.8e-27 93.9 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Thioredoxin_8 PF13905.1 CBZ54237.1 - 0.014 15.5 0.0 0.026 14.6 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin-like DUF1253 PF06862.7 CBZ54237.1 - 0.032 12.6 0.0 0.065 11.6 0.0 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1253) zf-C2H2_jaz PF12171.3 CBZ54238.1 - 9e-11 41.5 1.0 1.5e-10 40.9 0.7 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 CBZ54238.1 - 0.00068 19.7 0.3 0.0011 19.1 0.2 1.3 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 CBZ54238.1 - 0.028 14.5 0.0 0.034 14.2 0.0 1.2 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.21 CBZ54238.1 - 0.059 13.7 0.3 0.13 12.6 0.2 1.6 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-U1 PF06220.7 CBZ54238.1 - 0.091 12.3 0.2 0.18 11.3 0.1 1.4 1 0 0 1 1 1 0 U1 zinc finger IMCp PF12314.3 CBZ54240.1 - 1.5e-16 60.2 124.7 7.2e-09 35.6 14.5 5.6 1 1 4 5 5 5 4 Inner membrane complex protein E1-E2_ATPase PF00122.15 CBZ54241.1 - 1.7e-35 122.1 2.2 1.5e-25 89.5 0.0 2.6 2 0 0 2 2 2 2 E1-E2 ATPase Hydrolase PF00702.21 CBZ54241.1 - 1.6e-24 87.5 0.8 1e-16 61.9 0.3 2.5 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.2 CBZ54241.1 - 1.2e-09 38.6 1.2 1.6e-08 34.9 0.5 2.7 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase HMA PF00403.21 CBZ54241.1 - 4.5e-05 23.5 0.2 0.00012 22.1 0.0 1.9 2 0 0 2 2 2 1 Heavy-metal-associated domain DEAD PF00270.24 CBZ54242.1 - 1.3e-27 96.3 0.0 3.3e-27 95.0 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CBZ54242.1 - 7.6e-17 60.9 0.0 1.8e-16 59.7 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain PAP_central PF04928.12 CBZ54243.1 - 1.8e-91 305.4 0.1 2.5e-91 305.0 0.0 1.1 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.10 CBZ54243.1 - 6.9e-24 84.1 0.0 1.7e-23 82.9 0.0 1.6 1 1 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.18 CBZ54243.1 - 1e-09 38.5 0.0 2.1e-09 37.5 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain DUF4269 PF14091.1 CBZ54243.1 - 0.087 12.7 0.0 0.42 10.5 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4269) Macoilin PF09726.4 CBZ54243.1 - 4.2 5.5 6.0 6.2 4.9 4.2 1.2 1 0 0 1 1 1 0 Transmembrane protein PAP1 PF08601.5 CBZ54243.1 - 7.2 6.1 12.9 14 5.2 9.0 1.4 1 0 0 1 1 1 0 Transcription factor PAP1 DnaJ PF00226.26 CBZ54244.1 - 1e-18 66.8 0.1 2.5e-18 65.5 0.0 1.7 1 0 0 1 1 1 1 DnaJ domain Metallophos PF00149.23 CBZ54244.1 - 0.0054 16.1 3.7 0.0059 16.0 0.1 2.7 3 0 0 3 3 3 1 Calcineurin-like phosphoesterase PepSY_2 PF13670.1 CBZ54244.1 - 0.04 13.8 0.4 0.092 12.6 0.3 1.6 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain Aa_trans PF01490.13 CBZ54245.1 - 3.6e-56 190.3 0.2 1e-55 188.9 0.1 1.6 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 CBZ54245.1 - 0.00019 20.3 6.8 0.00019 20.3 4.7 1.6 2 0 0 2 2 2 1 Tryptophan/tyrosine permease family IBR PF01485.16 CBZ54246.1 - 5.5e-07 29.3 30.7 8.7e-05 22.3 8.1 4.4 4 1 0 4 4 4 3 IBR domain EF-hand_6 PF13405.1 CBZ54247.1 - 8.5e-09 34.5 0.0 0.00057 19.5 0.0 2.8 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.1 CBZ54247.1 - 2.1e-07 30.9 0.0 0.0063 16.6 0.0 2.4 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 CBZ54247.1 - 2.6e-07 29.4 0.2 0.0025 16.9 0.1 3.1 3 0 0 3 3 3 2 EF hand EF-hand_9 PF14658.1 CBZ54247.1 - 1.2e-06 28.3 0.0 0.045 13.6 0.0 2.8 2 1 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.1 CBZ54247.1 - 0.00018 21.0 1.6 1.9 8.1 0.0 3.9 3 1 1 4 4 4 2 EF-hand domain pair EF-hand_4 PF12763.2 CBZ54247.1 - 0.037 13.7 0.0 0.33 10.7 0.0 2.1 2 1 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand Pkinase PF00069.20 CBZ54248.1 - 8e-65 218.5 0.0 9.2e-65 218.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ54248.1 - 2.5e-35 121.8 0.0 3.1e-35 121.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBZ54248.1 - 7.4e-08 31.7 0.0 8.9e-08 31.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_C PF00433.19 CBZ54248.1 - 0.039 14.4 0.6 0.089 13.3 0.4 1.6 1 0 0 1 1 1 0 Protein kinase C terminal domain APH PF01636.18 CBZ54248.1 - 0.12 12.1 0.0 0.24 11.1 0.0 1.4 1 1 0 1 1 1 0 Phosphotransferase enzyme family MFS_2 PF13347.1 CBZ54249.1 - 2.6e-59 200.7 33.5 3.4e-59 200.3 23.2 1.1 1 0 0 1 1 1 1 MFS/sugar transport protein MFS_1 PF07690.11 CBZ54249.1 - 2.1e-16 59.6 34.2 3.6e-10 39.0 11.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Pterin_4a PF01329.14 CBZ54250.1 - 1.2e-32 111.5 1.2 1.4e-32 111.3 0.8 1.0 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase ATP-synt_DE_N PF02823.11 CBZ54251.1 - 1.5e-11 43.8 0.0 2.2e-11 43.3 0.0 1.2 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain Acyl_transf_1 PF00698.16 CBZ54252.1 - 1.1e-18 67.6 1.4 7.9e-17 61.5 1.0 2.1 1 1 0 1 1 1 1 Acyl transferase domain Med31 PF05669.7 CBZ54254.1 - 5.4e-33 112.8 2.6 6.5e-33 112.5 1.8 1.1 1 0 0 1 1 1 1 SOH1 Pkinase PF00069.20 CBZ54255.1 - 4.4e-42 144.0 0.0 1.1e-40 139.4 0.0 2.6 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ54255.1 - 7.5e-15 54.7 0.0 2.6e-11 43.1 0.0 3.1 3 1 0 3 3 3 2 Protein tyrosine kinase Dockerin_1 PF00404.13 CBZ54255.1 - 5.7 6.8 0.0 13 5.7 0.0 1.6 1 0 0 1 1 1 0 Dockerin type I repeat TIM PF00121.13 CBZ54258.1 - 4.5e-88 294.4 0.0 5.1e-88 294.2 0.0 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase PWWP PF00855.12 CBZ54262.1 - 8.6e-05 22.6 0.1 0.00019 21.5 0.1 1.5 1 0 0 1 1 1 1 PWWP domain Epimerase PF01370.16 CBZ54263.1 - 6.9e-49 166.4 0.0 9.1e-49 166.0 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Epimerase_Csub PF13950.1 CBZ54263.1 - 2.8e-25 87.9 0.2 5e-25 87.2 0.1 1.4 1 0 0 1 1 1 1 UDP-glucose 4-epimerase C-term subunit 3Beta_HSD PF01073.14 CBZ54263.1 - 4.7e-16 58.3 0.0 2.2e-14 52.8 0.0 2.2 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 CBZ54263.1 - 5.5e-13 48.4 0.0 7.5e-13 47.9 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein RmlD_sub_bind PF04321.12 CBZ54263.1 - 2.9e-12 46.1 0.0 1.4e-11 43.8 0.0 1.9 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.1 CBZ54263.1 - 6.8e-12 45.7 0.0 2e-09 37.6 0.0 2.2 1 1 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 CBZ54263.1 - 1.7e-11 43.5 0.0 4.3e-11 42.2 0.0 1.6 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.20 CBZ54263.1 - 9.2e-08 32.1 0.0 3.1e-07 30.4 0.0 1.8 1 1 0 1 1 1 1 short chain dehydrogenase UDPG_MGDP_dh_N PF03721.9 CBZ54263.1 - 0.00048 19.5 0.0 0.00075 18.9 0.0 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain KR PF08659.5 CBZ54263.1 - 0.00052 19.7 0.0 0.001 18.8 0.0 1.4 1 0 0 1 1 1 1 KR domain NAD_binding_2 PF03446.10 CBZ54263.1 - 0.012 15.4 0.0 0.022 14.6 0.0 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.13 CBZ54263.1 - 0.077 12.6 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Peptidase_M28 PF04389.12 CBZ54266.1 - 2e-19 70.0 0.7 3.5e-19 69.2 0.5 1.4 1 0 0 1 1 1 1 Peptidase family M28 BTV_NS2 PF04514.7 CBZ54267.1 - 2.6 6.8 8.8 3.7 6.3 6.1 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 CAF-1_p150 PF11600.3 CBZ54268.1 - 0.00054 19.4 43.8 0.00054 19.4 30.4 2.4 2 0 0 2 2 2 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal CDC27 PF09507.5 CBZ54268.1 - 0.52 9.4 30.4 1.1 8.4 21.1 1.4 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 DUF342 PF03961.8 CBZ54268.1 - 3.5 5.9 16.5 5.3 5.3 11.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) MIP-T3 PF10243.4 CBZ54268.1 - 6.9 5.0 41.6 13 4.1 28.8 1.3 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 CR6_interact PF10147.4 CBZ54270.1 - 0.05 12.9 0.6 0.05 12.9 0.4 2.0 2 1 1 3 3 3 0 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 ABC_tran PF00005.22 CBZ54271.1 - 1.3e-18 67.5 0.0 2.3e-18 66.8 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 CBZ54271.1 - 1.5e-06 28.3 0.3 3.4e-05 23.9 0.2 2.3 1 1 0 1 1 1 1 AAA domain SMC_N PF02463.14 CBZ54271.1 - 5.1e-06 25.8 0.2 0.063 12.4 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 CBZ54271.1 - 0.0018 17.7 0.1 0.0041 16.6 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_13 PF13166.1 CBZ54271.1 - 0.0019 16.7 0.0 0.0026 16.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 CBZ54271.1 - 0.0021 18.8 0.3 0.0083 16.9 0.1 2.2 1 1 1 2 2 2 1 AAA domain AAA_25 PF13481.1 CBZ54271.1 - 0.0093 15.3 0.0 0.1 11.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain MutS_V PF00488.16 CBZ54271.1 - 0.0095 15.3 0.0 0.56 9.5 0.0 2.1 2 0 0 2 2 2 1 MutS domain V DUF258 PF03193.11 CBZ54271.1 - 0.12 11.5 0.0 0.19 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Thioredoxin_8 PF13905.1 CBZ54272.1 - 1.3e-21 76.5 0.0 1.8e-21 76.0 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.16 CBZ54272.1 - 0.011 15.4 0.0 0.015 14.9 0.0 1.2 1 0 0 1 1 1 0 AhpC/TSA family Thioredoxin_2 PF13098.1 CBZ54272.1 - 0.071 13.3 0.0 0.11 12.6 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin-like domain Pkinase_Tyr PF07714.12 CBZ54274.1 - 3.8e-40 137.5 0.0 5.6e-40 137.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 CBZ54274.1 - 1e-38 132.9 0.0 2.9e-38 131.4 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Chorein_N PF12624.2 CBZ54275.1 - 1.9e-10 40.3 0.0 4.2e-10 39.1 0.0 1.5 1 0 0 1 1 1 1 N-terminal region of Chorein, a TM vesicle-mediated sorter Srg PF02118.16 CBZ54275.1 - 0.28 10.5 0.7 0.42 10.0 0.5 1.2 1 0 0 1 1 1 0 Srg family chemoreceptor DUF1162 PF06650.7 CBZ54275.1 - 1.5 7.9 0.0 2.8 7.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1162) DUF2951 PF11166.3 CBZ54275.1 - 6.3 6.7 1.0 14 5.6 0.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2951) DUF2508 PF10704.4 CBZ54275.1 - 8.7 6.6 0.0 25 5.1 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2508) CAGE1 PF15066.1 CBZ54275.1 - 8.8 4.6 3.5 14 3.9 2.4 1.2 1 0 0 1 1 1 0 Cancer-associated gene protein 1 family Tim17 PF02466.14 CBZ54278.1 - 4e-29 101.2 5.3 5.3e-29 100.8 3.7 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family PDZ_2 PF13180.1 CBZ54281.1 - 0.00041 20.1 0.0 0.014 15.2 0.0 2.2 2 0 0 2 2 2 1 PDZ domain GRASP55_65 PF04495.9 CBZ54281.1 - 0.0057 16.6 0.0 0.015 15.2 0.0 1.7 1 1 0 1 1 1 1 GRASP55/65 PDZ-like domain DUF2063 PF09836.4 CBZ54281.1 - 0.14 12.1 0.0 1.3 9.0 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2063) Filament PF00038.16 CBZ54282.1 - 0.0006 19.3 22.7 0.0006 19.3 15.7 6.1 2 1 3 6 6 6 4 Intermediate filament protein Trans_reg_C PF00486.23 CBZ54282.1 - 0.0024 17.7 0.9 6.1 6.8 0.0 3.8 3 1 0 3 3 3 2 Transcriptional regulatory protein, C terminal DUF948 PF06103.6 CBZ54282.1 - 0.0059 16.4 0.3 0.0059 16.4 0.2 8.8 4 2 4 8 8 8 1 Bacterial protein of unknown function (DUF948) LPP PF04728.8 CBZ54282.1 - 0.078 12.7 0.3 0.078 12.7 0.2 5.5 7 0 0 7 7 7 0 Lipoprotein leucine-zipper YqgF PF14639.1 CBZ54282.1 - 0.64 9.5 9.3 0.054 13.0 1.8 2.5 2 0 0 2 2 2 0 Holliday-junction resolvase-like of SPT6 YbjQ_1 PF01906.12 CBZ54282.1 - 4.1 7.8 6.3 37 4.8 0.4 3.5 2 1 0 2 2 2 0 Putative heavy-metal-binding HALZ PF02183.13 CBZ54283.1 - 0.011 15.4 0.8 0.011 15.4 0.6 2.8 2 0 0 2 2 2 0 Homeobox associated leucine zipper nec1 PF10379.4 CBZ54283.1 - 0.072 12.3 0.1 0.18 11.0 0.1 1.6 1 0 0 1 1 1 0 Virulence protein nec1 PS_Dcarbxylase PF02666.10 CBZ54284.1 - 3.1e-57 193.1 0.1 4.2e-57 192.7 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase Peptidase_M23 PF01551.17 CBZ54284.1 - 0.061 13.3 0.6 6.3 6.9 0.0 3.5 3 1 1 4 4 4 0 Peptidase family M23 Form-deh_trans PF09163.6 CBZ54284.1 - 0.24 10.9 2.1 0.45 10.0 0.5 2.2 2 0 0 2 2 2 0 Formate dehydrogenase N, transmembrane Fibrinogen_BP PF08017.6 CBZ54285.1 - 4.6e-05 21.7 0.0 8.7e-05 20.8 0.0 1.4 1 0 0 1 1 1 1 Fibrinogen binding protein Zip PF02535.17 CBZ54286.1 - 1.4e-29 103.0 24.1 5.4e-18 65.0 10.4 3.5 3 1 0 4 4 4 2 ZIP Zinc transporter RAP PF08373.5 CBZ54287.1 - 6.7e-13 48.2 0.0 1.2e-12 47.3 0.0 1.4 1 0 0 1 1 1 1 RAP domain SYS1 PF09801.4 CBZ54289.1 - 2.4e-21 76.2 1.5 8.9e-16 58.1 0.3 2.1 2 0 0 2 2 2 2 Integral membrane protein S linking to the trans Golgi network Glucan_synthase PF02364.10 CBZ54289.1 - 0.082 10.7 0.4 0.16 9.8 0.3 1.4 1 0 0 1 1 1 0 1,3-beta-glucan synthase component Pkinase PF00069.20 CBZ54290.1 - 2.7e-70 236.4 0.0 3.7e-70 236.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ54290.1 - 1.6e-28 99.4 0.0 2.2e-28 99.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_1 PF00036.27 CBZ54290.1 - 1.9e-24 83.0 0.0 9.8e-06 24.5 0.1 4.6 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 CBZ54290.1 - 1.5e-22 79.5 0.1 5.9e-10 39.1 0.1 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 CBZ54290.1 - 1.7e-19 67.8 0.0 0.0003 20.4 0.0 4.6 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 CBZ54290.1 - 6e-17 60.1 0.2 1.8e-05 23.8 0.0 4.5 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.1 CBZ54290.1 - 7.5e-17 60.6 0.4 0.00014 21.4 0.0 4.1 2 1 2 4 4 4 4 EF-hand domain pair CBM_20 PF00686.14 CBZ54290.1 - 4.6e-13 48.5 0.1 7.9e-13 47.8 0.0 1.3 1 0 0 1 1 1 1 Starch binding domain SPARC_Ca_bdg PF10591.4 CBZ54290.1 - 1.7e-06 28.0 0.0 0.0012 18.8 0.0 2.4 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 CBZ54290.1 - 6.1e-05 22.7 0.0 0.076 12.7 0.0 2.4 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand Kdo PF06293.9 CBZ54290.1 - 0.00077 18.5 0.1 0.0021 17.1 0.0 1.6 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 CBZ54290.1 - 0.058 12.3 0.0 0.13 11.2 0.0 1.5 1 0 0 1 1 1 0 Kinase-like EF-hand_9 PF14658.1 CBZ54290.1 - 0.089 12.7 0.0 20 5.1 0.0 2.5 2 0 0 2 2 2 0 EF-hand domain V-ATPase_G PF03179.10 CBZ54291.1 - 0.00029 21.0 7.0 0.00057 20.1 4.9 1.5 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit PMSR PF01625.16 CBZ54292.1 - 9e-52 175.0 0.2 1.2e-51 174.6 0.1 1.2 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase SlyX PF04102.7 CBZ54293.1 - 0.0035 17.6 0.3 0.0035 17.6 0.2 2.5 3 0 0 3 3 3 1 SlyX FliJ PF02050.11 CBZ54293.1 - 0.0051 16.8 0.3 0.0051 16.8 0.2 2.2 2 1 0 2 2 2 1 Flagellar FliJ protein DivIC PF04977.10 CBZ54293.1 - 0.0081 15.6 4.3 0.056 12.9 0.3 2.4 2 0 0 2 2 2 1 Septum formation initiator Fez1 PF06818.10 CBZ54293.1 - 0.076 13.0 2.6 0.15 12.0 1.8 1.4 1 1 0 1 1 1 0 Fez1 DUF4407 PF14362.1 CBZ54293.1 - 0.08 11.8 2.4 0.11 11.4 1.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) PhaP_Bmeg PF09602.5 CBZ54293.1 - 0.67 9.7 4.2 0.78 9.5 0.1 2.3 2 1 0 2 2 2 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) PCI PF01399.22 CBZ54294.1 - 0.03 14.6 1.5 0.059 13.6 1.1 1.4 1 0 0 1 1 1 0 PCI domain Tropomyosin_1 PF12718.2 CBZ54294.1 - 0.04 13.7 0.1 4.3 7.1 0.1 2.3 2 0 0 2 2 2 0 Tropomyosin like Gtr1_RagA PF04670.7 CBZ54296.1 - 7.8e-67 224.8 0.1 3.9e-33 114.5 0.0 2.1 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Arf PF00025.16 CBZ54296.1 - 2.2e-05 23.7 0.0 0.00011 21.4 0.0 1.9 2 0 0 2 2 2 1 ADP-ribosylation factor family Ras PF00071.17 CBZ54296.1 - 0.0011 18.4 0.0 0.0025 17.2 0.0 1.6 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CBZ54296.1 - 0.0014 19.1 0.0 0.003 18.0 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein ABC_tran PF00005.22 CBZ54296.1 - 0.014 15.6 0.0 0.028 14.7 0.0 1.5 1 0 0 1 1 1 0 ABC transporter MMR_HSR1 PF01926.18 CBZ54296.1 - 0.018 15.0 0.0 0.046 13.6 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase Macoilin PF09726.4 CBZ54296.1 - 8.2 4.5 9.5 11 4.1 6.6 1.2 1 0 0 1 1 1 0 Transmembrane protein HIT PF01230.18 CBZ54297.1 - 1.6e-12 47.8 0.0 2.1e-12 47.4 0.0 1.2 1 0 0 1 1 1 1 HIT domain AMMECR1 PF01871.12 CBZ54298.1 - 3.1e-22 78.5 0.0 1.4e-21 76.3 0.0 2.0 2 1 0 2 2 2 1 AMMECR1 Histone PF00125.19 CBZ54299.1 - 9.2e-22 76.9 0.6 2.2e-21 75.7 0.0 1.8 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 CBZ54299.1 - 0.13 12.3 0.0 0.25 11.4 0.0 1.3 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Dmrt1 PF12374.3 CBZ54303.1 - 0.00062 20.0 0.2 0.76 10.1 0.0 3.7 3 0 0 3 3 3 2 Double-sex mab3 related transcription factor 1 TMEM18 PF14770.1 CBZ54304.1 - 6.2e-07 28.9 3.4 6.2e-07 28.9 2.3 1.5 2 0 0 2 2 2 1 Transmembrane protein 18 WTF PF03303.8 CBZ54306.1 - 1.9 7.8 7.3 3.2 7.0 5.1 1.3 1 0 0 1 1 1 0 WTF protein MTHFR_C PF12225.3 CBZ54307.1 - 6 6.4 10.8 13 5.3 0.3 2.3 2 0 0 2 2 2 0 Methylene-tetrahydrofolate reductase C terminal ArfGap PF01412.13 CBZ54308.1 - 0.011 15.5 0.7 0.018 14.7 0.1 1.7 2 0 0 2 2 2 0 Putative GTPase activating protein for Arf ACBP PF00887.14 CBZ54309.1 - 0.0019 17.8 3.8 0.0033 17.0 2.6 1.4 1 0 0 1 1 1 1 Acyl CoA binding protein HutP PF09021.6 CBZ54309.1 - 0.24 11.6 1.1 0.47 10.6 0.7 1.5 1 0 0 1 1 1 0 HutP HCMV_UL139 PF12507.3 CBZ54309.1 - 0.28 11.3 7.9 0.078 13.1 2.7 2.0 1 1 1 2 2 2 0 Human Cytomegalovirus UL139 protein Metal_resist PF13801.1 CBZ54309.1 - 0.51 10.3 12.1 0.1 12.6 3.9 2.2 2 0 0 2 2 2 0 Heavy-metal resistance DUF4613 PF15390.1 CBZ54309.1 - 0.78 7.8 6.5 1 7.4 4.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) Occludin_ELL PF07303.8 CBZ54309.1 - 2.1 9.1 18.4 0.09 13.5 5.3 2.4 1 1 1 2 2 2 0 Occludin homology domain RNF111_N PF15303.1 CBZ54309.1 - 2.2 7.7 9.1 0.75 9.2 4.0 1.9 1 1 0 1 1 1 0 E3 ubiquitin-protein ligase Arkadia N-terminus DUF1911 PF08929.5 CBZ54309.1 - 2.3 8.9 7.7 0.47 11.1 1.8 2.3 1 1 0 2 2 2 0 Domain of unknown function (DUF1911) GDA1_CD39 PF01150.12 CBZ54310.1 - 9.9e-09 34.1 0.0 4.3e-08 32.0 0.0 1.8 2 0 0 2 2 2 1 GDA1/CD39 (nucleoside phosphatase) family MscS_porin PF12795.2 CBZ54312.1 - 0.00016 21.1 7.6 0.00016 21.1 5.3 2.4 2 0 0 2 2 2 1 Mechanosensitive ion channel porin domain RNA_pol_Rpb1_1 PF04997.7 CBZ54313.1 - 1.4e-99 333.5 0.0 2.5e-99 332.7 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.12 CBZ54313.1 - 3.1e-99 331.7 0.1 4.8e-99 331.1 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.15 CBZ54313.1 - 4.4e-66 221.9 0.0 8.6e-66 220.9 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.9 CBZ54313.1 - 2.8e-47 160.8 2.5 5.6e-47 159.9 1.8 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_3 PF04983.13 CBZ54313.1 - 2.1e-45 154.3 0.0 4.3e-45 153.2 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_7 PF04990.7 CBZ54313.1 - 4.7e-43 146.1 2.1 1.2e-42 144.8 0.3 2.4 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_4 PF05000.12 CBZ54313.1 - 1.9e-39 133.7 0.1 4.7e-39 132.4 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 Ribosomal_L14 PF00238.14 CBZ54314.1 - 4.3e-26 91.0 0.6 5e-26 90.8 0.4 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Ribosomal_L13 PF00572.13 CBZ54315.1 - 3.1e-36 124.2 0.0 4.3e-36 123.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L13 CAP PF00188.21 CBZ54317.1 - 0.0026 18.2 0.1 0.0049 17.3 0.1 1.5 1 0 0 1 1 1 1 Cysteine-rich secretory protein family CAP PF00188.21 CBZ54318.1 - 0.0088 16.5 0.1 0.026 15.0 0.0 1.8 2 0 0 2 2 2 1 Cysteine-rich secretory protein family PilX_N PF14341.1 CBZ54319.1 - 5.3 6.7 22.9 18 5.0 0.1 6.3 6 0 0 6 6 6 0 PilX N-terminal Ins_P5_2-kin PF06090.7 CBZ54320.1 - 2.2e-12 46.6 0.0 3.4e-10 39.4 0.0 3.0 1 1 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase Tetraspannin PF00335.15 CBZ54322.1 - 0.023 13.9 0.0 0.042 13.1 0.0 1.4 1 0 0 1 1 1 0 Tetraspanin family BT1 PF03092.11 CBZ54323.1 - 1.2e-59 202.1 17.7 2.1e-59 201.3 12.3 1.3 1 1 0 1 1 1 1 BT1 family Rhomboid PF01694.17 CBZ54323.1 - 9 6.3 23.5 1.6 8.7 0.9 4.2 5 0 0 5 5 5 0 Rhomboid family YtfJ_HI0045 PF09695.5 CBZ54324.1 - 0.082 12.2 0.2 0.16 11.2 0.1 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (YtfJ_HI0045) S1 PF00575.18 CBZ54325.1 - 1.3e-18 66.8 0.4 3.1e-05 23.9 0.4 9.5 9 1 0 9 9 9 5 S1 RNA binding domain TPR_14 PF13428.1 CBZ54325.1 - 1.5e-06 28.3 0.3 0.51 11.1 0.0 5.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.1 CBZ54325.1 - 0.0024 18.1 4.5 0.92 10.1 0.0 4.8 4 0 0 4 4 4 2 Tetratricopeptide repeat Suf PF05843.9 CBZ54325.1 - 0.0073 16.0 5.6 0.94 9.1 0.3 3.2 2 0 0 2 2 2 2 Suppressor of forked protein (Suf) TPR_2 PF07719.12 CBZ54325.1 - 0.68 9.9 5.7 8 6.6 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat AP2 PF00847.15 CBZ54327.1 - 3.9e-08 33.3 1.4 9e-08 32.1 1.0 1.6 1 0 0 1 1 1 1 AP2 domain Snf7 PF03357.16 CBZ54328.1 - 7.4e-07 28.7 1.6 1.2e-06 28.0 0.1 1.9 2 1 0 2 2 2 1 Snf7 DivIVA PF05103.8 CBZ54330.1 - 0.1 12.6 2.6 0.12 12.4 0.7 1.8 2 0 0 2 2 2 0 DivIVA protein DivIC PF04977.10 CBZ54330.1 - 1.6 8.2 5.5 14 5.2 0.8 2.3 2 0 0 2 2 2 0 Septum formation initiator Ribosomal_S13 PF00416.17 CBZ54332.1 - 1.9e-37 127.9 1.8 2.4e-37 127.6 1.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.6 CBZ54332.1 - 0.0036 15.9 0.0 0.0036 15.9 0.0 1.1 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) SecA_SW PF07516.8 CBZ54332.1 - 0.092 12.5 0.1 0.11 12.2 0.1 1.1 1 0 0 1 1 1 0 SecA Wing and Scaffold domain GM_CSF PF01109.12 CBZ54333.1 - 0.019 14.9 0.2 0.037 13.9 0.1 1.5 1 0 0 1 1 1 0 Granulocyte-macrophage colony-stimulating factor RPA_interact_C PF14768.1 CBZ54333.1 - 0.09 13.1 1.6 0.36 11.2 1.1 2.1 1 0 0 1 1 1 0 Replication protein A interacting C-terminal Thioredoxin_8 PF13905.1 CBZ54334.1 - 3.2e-28 97.6 0.0 6.4e-28 96.7 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like PUB PF09409.5 CBZ54334.1 - 2e-11 43.4 0.0 9.2e-11 41.3 0.0 1.9 2 0 0 2 2 2 1 PUB domain Thioredoxin_2 PF13098.1 CBZ54334.1 - 7.2e-10 39.0 0.0 1.7e-09 37.8 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin PF00085.15 CBZ54334.1 - 2.5e-09 36.7 0.0 5e-06 26.1 0.0 2.6 1 1 1 2 2 2 2 Thioredoxin AhpC-TSA PF00578.16 CBZ54334.1 - 3.2e-07 30.0 0.0 5.2e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 CBZ54334.1 - 1.6e-06 27.7 0.0 3.4e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 Redoxin Thioredoxin_7 PF13899.1 CBZ54334.1 - 0.00038 20.4 0.1 0.0011 18.9 0.0 1.8 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_9 PF14595.1 CBZ54334.1 - 0.00054 19.5 0.0 0.0064 16.0 0.0 2.2 1 1 0 1 1 1 1 Thioredoxin Glutaredoxin PF00462.19 CBZ54334.1 - 0.072 13.0 0.0 0.3 11.1 0.0 2.0 1 1 0 1 1 1 0 Glutaredoxin DUF953 PF06110.6 CBZ54334.1 - 0.085 12.3 0.0 2.5 7.5 0.0 2.4 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF953) AdoHcyase PF05221.12 CBZ54335.1 - 8.4e-133 441.3 0.0 9.7e-133 441.1 0.0 1.0 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.16 CBZ54335.1 - 5.9e-79 263.5 1.8 8.9e-79 263.0 1.2 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.14 CBZ54335.1 - 1e-08 34.5 0.3 1.8e-08 33.7 0.2 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.7 CBZ54335.1 - 0.001 18.4 0.3 0.0021 17.4 0.2 1.5 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain TrkA_N PF02254.13 CBZ54335.1 - 0.0016 18.4 0.1 0.0035 17.3 0.1 1.6 1 0 0 1 1 1 1 TrkA-N domain TMEM107 PF14995.1 CBZ54335.1 - 0.0019 18.3 0.3 0.0036 17.4 0.2 1.4 1 0 0 1 1 1 1 Transmembrane protein ELFV_dehydrog PF00208.16 CBZ54335.1 - 0.0041 16.7 0.2 0.0079 15.8 0.1 1.5 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase NAD_binding_7 PF13241.1 CBZ54335.1 - 0.0071 16.5 0.3 0.016 15.4 0.2 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding THF_DHG_CYH_C PF02882.14 CBZ54335.1 - 0.013 14.5 1.6 0.063 12.3 1.1 2.0 1 1 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain AlaDh_PNT_C PF01262.16 CBZ54335.1 - 0.022 14.3 2.3 0.047 13.2 0.7 1.8 1 1 1 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.13 CBZ54335.1 - 0.079 12.6 1.0 0.13 11.8 0.7 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Filament PF00038.16 CBZ54336.1 - 0.0017 17.8 42.1 0.0017 17.8 29.1 7.6 2 2 5 7 7 7 3 Intermediate filament protein DUF2217 PF10265.4 CBZ54338.1 - 0.37 9.5 12.4 0.64 8.7 8.6 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) AF-4 PF05110.8 CBZ54338.1 - 1.6 6.4 37.1 0.028 12.3 15.8 2.3 2 0 0 2 2 2 0 AF-4 proto-oncoprotein CytochromB561_N PF09786.4 CBZ54338.1 - 5.3 5.3 14.0 11 4.2 9.7 1.5 1 0 0 1 1 1 0 Cytochrome B561, N terminal EPL1 PF10513.4 CBZ54339.1 - 5e-09 36.5 0.0 5e-09 36.5 0.0 2.8 3 1 0 3 3 3 1 Enhancer of polycomb-like L51_S25_CI-B8 PF05047.11 CBZ54340.1 - 0.012 15.2 0.0 0.021 14.5 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain Nop52 PF05997.7 CBZ54342.1 - 3.9e-28 98.3 0.8 3e-26 92.2 0.1 2.1 2 0 0 2 2 2 2 Nucleolar protein,Nop52 Sec66 PF09802.4 CBZ54343.1 - 1e-11 44.5 7.2 1.1e-11 44.5 4.2 1.6 1 1 0 1 1 1 1 Preprotein translocase subunit Sec66 DUF607 PF04678.8 CBZ54343.1 - 0.43 10.4 3.6 0.75 9.6 2.5 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF607 CT47 PF15623.1 CBZ54343.1 - 2.4 7.8 16.9 0.23 11.1 0.2 2.1 2 0 0 2 2 2 0 Cancer/testis gene family 47 DUF1510 PF07423.6 CBZ54343.1 - 5.9 6.1 12.4 3 7.1 6.9 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) Pkinase PF00069.20 CBZ54344.1 - 1.4e-75 253.8 0.0 2.1e-75 253.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ54344.1 - 6.3e-35 120.4 0.0 1e-34 119.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_1 PF00036.27 CBZ54344.1 - 1.8e-29 98.7 8.6 1.7e-07 30.0 0.7 4.6 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 CBZ54344.1 - 2.4e-26 91.6 1.1 4.1e-13 49.2 0.2 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 CBZ54344.1 - 1.9e-25 86.4 1.9 3.7e-07 29.4 0.0 4.6 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.1 CBZ54344.1 - 1e-22 79.4 10.5 2.5e-11 43.0 1.3 4.2 2 2 2 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.1 CBZ54344.1 - 1.8e-21 74.4 8.2 1.4e-07 30.4 0.2 4.7 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.1 CBZ54344.1 - 3.5e-07 30.0 0.3 0.00019 21.2 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.2 CBZ54344.1 - 8.1e-06 25.5 0.9 0.18 11.5 0.3 2.6 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 CBZ54344.1 - 5.1e-05 23.2 0.7 0.063 13.3 0.0 2.5 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region Kinase-like PF14531.1 CBZ54344.1 - 0.0036 16.3 0.0 0.017 14.0 0.0 1.8 1 1 1 2 2 2 1 Kinase-like APH PF01636.18 CBZ54344.1 - 0.0039 16.9 0.2 0.035 13.8 0.0 2.6 3 1 0 3 3 3 1 Phosphotransferase enzyme family DUF1103 PF06513.6 CBZ54344.1 - 0.024 14.0 1.3 0.04 13.3 0.9 1.3 1 0 0 1 1 1 0 Repeat of unknown function (DUF1103) TerB PF05099.8 CBZ54344.1 - 0.04 13.6 0.4 0.47 10.1 0.1 2.1 1 1 1 2 2 2 0 Tellurite resistance protein TerB Kdo PF06293.9 CBZ54344.1 - 0.095 11.7 0.0 0.26 10.3 0.0 1.7 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RNase_Zc3h12a PF11977.3 CBZ54345.1 - 0.19 11.5 0.0 0.57 10.0 0.0 1.7 1 1 0 1 1 1 0 Zc3h12a-like Ribonuclease NYN domain PqiA PF04403.8 CBZ54346.1 - 0.02 14.5 10.5 0.72 9.4 7.3 2.4 1 1 0 1 1 1 0 Paraquat-inducible protein A JmjC PF02373.17 CBZ54347.1 - 6e-10 39.3 0.1 0.00027 21.1 0.0 2.5 2 0 0 2 2 2 2 JmjC domain, hydroxylase Cupin_8 PF13621.1 CBZ54347.1 - 0.03 13.8 0.0 0.087 12.3 0.0 1.6 1 1 0 1 1 1 0 Cupin-like domain CutA1 PF03091.10 CBZ54349.1 - 1.3e-32 111.4 0.2 2e-32 110.8 0.2 1.2 1 0 0 1 1 1 1 CutA1 divalent ion tolerance protein ADK PF00406.17 CBZ54350.1 - 2.2e-55 186.6 0.0 2.8e-55 186.3 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase ADK_lid PF05191.9 CBZ54350.1 - 1.2e-13 50.4 0.0 2.6e-13 49.3 0.0 1.6 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_33 PF13671.1 CBZ54350.1 - 1e-07 31.9 0.0 1.7e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 CBZ54350.1 - 2.2e-07 31.7 0.0 4.2e-07 30.7 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 CBZ54350.1 - 0.00033 20.9 0.3 0.0013 18.9 0.1 2.1 2 1 0 2 2 2 1 AAA domain DAP3 PF10236.4 CBZ54350.1 - 0.12 11.3 0.0 0.6 8.9 0.0 2.0 1 1 1 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 AMP-binding PF00501.23 CBZ54351.1 - 5.7e-18 64.5 0.1 1e-06 27.4 0.0 3.9 3 1 0 3 3 3 3 AMP-binding enzyme Fer4_18 PF13746.1 CBZ54351.1 - 0.0093 16.3 7.1 0.051 13.9 4.9 2.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Kinesin PF00225.18 CBZ54352.1 - 3.8e-86 288.8 1.0 5.7e-86 288.2 0.7 1.3 1 0 0 1 1 1 1 Kinesin motor domain Spatacsin_C PF14649.1 CBZ54353.1 - 4.4e-23 81.5 1.4 1.1e-13 50.7 0.0 3.2 3 0 0 3 3 3 3 Spatacsin C-terminus ECR1_N PF14382.1 CBZ54354.1 - 1.5e-10 40.1 0.2 2.8e-10 39.3 0.2 1.5 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region RRM_1 PF00076.17 CBZ54355.1 - 9.3e-75 246.2 0.3 1.2e-20 72.9 0.1 4.3 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBZ54355.1 - 4.3e-52 173.9 0.2 7.3e-15 54.7 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBZ54355.1 - 1.7e-39 133.4 0.0 3.7e-10 39.5 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.13 CBZ54355.1 - 4.3e-31 106.4 2.3 1.1e-30 105.0 1.6 1.8 1 0 0 1 1 1 1 Poly-adenylate binding protein, unique domain Nup35_RRM_2 PF14605.1 CBZ54355.1 - 0.00059 19.5 0.0 4.5 7.1 0.0 4.0 4 0 0 4 4 4 1 Nup53/35/40-type RNA recognition motif PDEase_I PF00233.14 CBZ54356.1 - 1.5e-40 139.4 0.9 6.5e-37 127.5 0.6 2.4 1 1 1 2 2 2 2 3'5'-cyclic nucleotide phosphodiesterase HD PF01966.17 CBZ54356.1 - 0.00073 19.5 0.1 0.0021 18.0 0.0 1.8 2 0 0 2 2 2 1 HD domain Thy1 PF02511.10 CBZ54356.1 - 0.069 12.4 0.2 0.17 11.1 0.0 1.7 2 0 0 2 2 2 0 Thymidylate synthase complementing protein ABM PF03992.11 CBZ54358.1 - 0.023 14.6 0.1 0.11 12.5 0.0 1.9 1 1 0 1 1 1 0 Antibiotic biosynthesis monooxygenase Herpes_capsid PF06112.6 CBZ54358.1 - 3.5 7.6 6.9 1 9.3 2.2 1.8 2 0 0 2 2 2 0 Gammaherpesvirus capsid protein ER_lumen_recept PF00810.13 CBZ54360.1 - 2.7e-20 73.3 13.4 2.7e-20 73.3 9.3 2.1 2 1 0 2 2 2 1 ER lumen protein retaining receptor SAG PF04092.8 CBZ54362.1 - 1.7e-61 206.1 14.6 6.9e-37 126.5 3.0 2.1 2 0 0 2 2 2 2 SRS domain SAG PF04092.8 CBZ54363.1 - 2.8e-56 189.2 17.4 2e-34 118.6 3.7 2.1 2 0 0 2 2 2 2 SRS domain SAG PF04092.8 CBZ54364.1 - 2e-60 202.6 17.6 4.4e-37 127.2 2.8 2.1 2 0 0 2 2 2 2 SRS domain SAG PF04092.8 CBZ54365.1 - 1.3e-52 177.4 17.9 1.7e-31 109.1 2.7 2.2 2 0 0 2 2 2 2 SRS domain YfhO PF09586.5 CBZ54365.1 - 0.048 11.6 0.1 0.059 11.3 0.1 1.1 1 0 0 1 1 1 0 Bacterial membrane protein YfhO SAG PF04092.8 CBZ54366.1 - 4.1e-58 195.1 18.3 1.2e-34 119.3 2.0 2.1 2 0 0 2 2 2 2 SRS domain E_Pc_C PF06752.7 CBZ54368.1 - 0.035 13.6 7.9 0.06 12.8 5.5 1.3 1 0 0 1 1 1 0 Enhancer of Polycomb C-terminus MPP6 PF10175.4 CBZ54368.1 - 0.05 13.9 2.5 0.31 11.4 0.2 2.6 2 2 0 2 2 2 0 M-phase phosphoprotein 6 TEX13 PF15186.1 CBZ54368.1 - 0.6 9.6 8.1 0.097 12.2 0.8 2.3 2 0 0 2 2 2 0 Testis-expressed sequence 13 protein family DUF3138 PF11336.3 CBZ54368.1 - 5.1 5.1 5.4 7.2 4.6 3.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) PI3_PI4_kinase PF00454.22 CBZ54369.1 - 4.7e-20 72.0 0.0 2.8e-16 59.7 0.0 2.3 2 0 0 2 2 2 2 Phosphatidylinositol 3- and 4-kinase FATC PF02260.15 CBZ54369.1 - 0.0067 15.8 0.1 0.026 13.9 0.0 2.1 2 0 0 2 2 2 1 FATC domain NUC194 PF08163.7 CBZ54369.1 - 0.35 9.6 0.1 0.61 8.8 0.1 1.3 1 0 0 1 1 1 0 NUC194 domain DUF2593 PF10767.4 CBZ54369.1 - 3.6 7.2 0.0 14 5.4 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2593) XK-related PF09815.4 CBZ54369.1 - 4.1 6.3 0.0 57 2.5 0.0 2.1 2 0 0 2 2 2 0 XK-related protein PRP38 PF03371.10 CBZ54370.1 - 1.6e-56 190.6 0.0 2.5e-56 189.9 0.0 1.3 1 0 0 1 1 1 1 PRP38 family RCC1 PF00415.13 CBZ54371.1 - 2e-55 184.7 20.0 4.1e-12 46.1 0.1 9.7 9 0 0 9 9 9 9 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 CBZ54371.1 - 1.6e-29 100.8 29.8 3.8e-11 42.2 0.3 7.5 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat Ribosomal_S2 PF00318.15 CBZ54372.1 - 1.2e-44 152.1 0.1 3.1e-21 75.5 0.0 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 Ribosomal_L31e PF01198.14 CBZ54373.1 - 1.8e-38 130.0 1.8 2.3e-38 129.7 1.3 1.1 1 0 0 1 1 1 1 Ribosomal protein L31e Rootletin PF15035.1 CBZ54374.1 - 0.036 14.0 8.8 0.081 12.8 6.1 1.5 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion HAUS-augmin3 PF14932.1 CBZ54374.1 - 0.14 11.3 6.7 0.22 10.6 4.6 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 Nup54 PF13874.1 CBZ54374.1 - 0.2 11.3 7.3 0.36 10.4 5.1 1.4 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 TMPIT PF07851.8 CBZ54374.1 - 1.1 8.2 3.7 1.7 7.6 2.6 1.2 1 0 0 1 1 1 0 TMPIT-like protein Noelin-1 PF12308.3 CBZ54374.1 - 1.6 8.5 5.8 2.6 7.8 2.5 2.3 2 1 0 2 2 2 0 Neurogenesis glycoprotein Sigma70_ner PF04546.8 CBZ54374.1 - 2.7 7.5 8.8 1 8.9 3.6 2.1 3 0 0 3 3 3 0 Sigma-70, non-essential region DUF1625 PF07787.7 CBZ54375.1 - 1.3e-17 63.8 0.0 1.8e-17 63.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1625) Pkinase PF00069.20 CBZ54376.1 - 2.1e-24 86.0 0.0 3.6e-24 85.3 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.1 CBZ54376.1 - 6.6e-23 81.0 0.0 1.2e-22 80.2 0.0 1.4 1 1 0 1 1 1 1 Kinase-like Pkinase_Tyr PF07714.12 CBZ54376.1 - 2.9e-08 33.0 0.0 6.9e-08 31.8 0.0 1.7 1 1 1 2 2 2 1 Protein tyrosine kinase Kdo PF06293.9 CBZ54376.1 - 0.082 11.9 0.0 0.18 10.8 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DEAD PF00270.24 CBZ54377.1 - 4.1e-27 94.7 0.0 1.5e-26 92.9 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CBZ54377.1 - 3.2e-24 84.5 0.0 7.7e-24 83.3 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 CBZ54377.1 - 0.001 18.9 0.0 0.0024 17.7 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_25 PF13481.1 CBZ54377.1 - 0.13 11.6 0.5 0.59 9.5 0.3 2.1 1 1 0 1 1 1 0 AAA domain GSHPx PF00255.14 CBZ54378.1 - 3.7e-22 77.7 0.1 5.1e-22 77.3 0.0 1.2 1 0 0 1 1 1 1 Glutathione peroxidase Peptidase_M50 PF02163.17 CBZ54379.1 - 4.3e-13 48.6 3.8 6.8e-13 48.0 2.6 1.2 1 0 0 1 1 1 1 Peptidase family M50 Acyl-CoA_dh_1 PF00441.19 CBZ54381.1 - 4.2e-44 150.2 3.6 6.6e-44 149.6 2.5 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 CBZ54381.1 - 5.7e-20 71.9 0.0 2.2e-19 70.0 0.0 2.0 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 CBZ54381.1 - 1.4e-18 67.4 0.8 2.4e-18 66.6 0.5 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 CBZ54381.1 - 1.2e-15 56.7 0.1 2.1e-15 55.9 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain MMR_HSR1_C PF08438.5 CBZ54382.1 - 9.1e-27 93.4 0.1 1.6e-26 92.6 0.1 1.4 1 0 0 1 1 1 1 GTPase of unknown function C-terminal MMR_HSR1 PF01926.18 CBZ54382.1 - 1.6e-18 66.7 0.0 4.4e-18 65.3 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 CBZ54382.1 - 1.4e-09 37.3 1.2 1.7e-06 27.3 0.2 2.5 2 0 0 2 2 2 2 Ferrous iron transport protein B ATP_bind_1 PF03029.12 CBZ54382.1 - 0.007 15.9 0.6 0.41 10.1 0.0 2.4 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.22 CBZ54382.1 - 0.17 11.3 0.1 1.8 7.9 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain HTH_9 PF08221.6 CBZ54383.1 - 0.00014 21.6 1.0 0.087 12.7 0.1 2.9 2 0 0 2 2 2 2 RNA polymerase III subunit RPC82 helix-turn-helix domain RNA_pol_Rpc82 PF05645.8 CBZ54383.1 - 0.094 12.2 0.1 0.21 11.1 0.0 1.7 1 0 0 1 1 1 0 RNA polymerase III subunit RPC82 RRM_1 PF00076.17 CBZ54384.1 - 2.2e-43 145.7 0.0 1.4e-21 75.9 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBZ54384.1 - 6.7e-27 93.2 0.0 1.4e-12 47.3 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBZ54384.1 - 1.2e-19 69.8 0.0 1.1e-09 37.9 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OB_RNB PF08206.6 CBZ54384.1 - 0.007 15.8 0.2 1.5 8.3 0.1 2.3 2 0 0 2 2 2 2 Ribonuclease B OB domain DUF819 PF05684.7 CBZ54385.1 - 4.8e-19 68.4 22.5 3.4e-13 49.1 3.2 3.8 3 2 0 3 3 3 3 Protein of unknown function (DUF819) Myosin_head PF00063.16 CBZ54386.1 - 0.0061 14.6 0.0 0.032 12.3 0.0 2.2 2 0 0 2 2 2 1 Myosin head (motor domain) FtsL PF04999.8 CBZ54386.1 - 3.8 7.2 5.1 8.3 6.2 3.5 1.5 1 0 0 1 1 1 0 Cell division protein FtsL IMCp PF12314.3 CBZ54387.1 - 3.6e-29 100.7 27.7 3.6e-29 100.7 19.2 2.1 1 1 1 2 2 2 2 Inner membrane complex protein IMCp PF12314.3 CBZ54388.1 - 8.8e-23 80.2 44.3 1e-16 60.8 14.4 2.1 1 1 1 2 2 2 2 Inner membrane complex protein Ste5 PF11610.3 CBZ54388.1 - 0.81 9.2 4.7 0.57 9.7 0.6 2.3 2 0 0 2 2 2 0 Scaffold protein Ste5-Fus5 binding region Baculo_p47 PF05112.7 CBZ54389.1 - 0.67 9.2 0.0 1.2 8.5 0.0 1.2 1 0 0 1 1 1 0 Baculovirus P47 protein polyprenyl_synt PF00348.12 CBZ54390.1 - 6.9e-44 149.6 0.0 1.6e-40 138.6 0.0 3.1 2 1 0 2 2 2 2 Polyprenyl synthetase Pkinase PF00069.20 CBZ54391.1 - 5.8e-47 160.0 0.0 9.1e-47 159.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ54391.1 - 3.3e-15 55.8 0.0 5.8e-15 55.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase DUF3458 PF11940.3 CBZ54393.1 - 9.8e-84 281.2 0.4 9.6e-70 235.2 0.1 2.3 1 1 1 2 2 2 2 Domain of unknown function (DUF3458) Peptidase_M1 PF01433.15 CBZ54393.1 - 1.7e-45 155.8 0.0 4.5e-27 95.1 0.0 2.2 2 0 0 2 2 2 2 Peptidase family M1 Peptidase_MA_2 PF13485.1 CBZ54393.1 - 1.3e-08 34.9 0.0 3.5e-08 33.5 0.0 1.8 1 0 0 1 1 1 1 Peptidase MA superfamily Peptidase_M61 PF05299.7 CBZ54393.1 - 0.018 14.9 0.0 0.041 13.8 0.0 1.6 1 0 0 1 1 1 0 M61 glycyl aminopeptidase DUF3458 PF11940.3 CBZ54394.1 - 5.5e-119 397.2 4.8 7.9e-119 396.7 3.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3458) Peptidase_M1 PF01433.15 CBZ54394.1 - 1.1e-68 232.1 0.0 1.6e-68 231.5 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M1 Peptidase_MA_2 PF13485.1 CBZ54394.1 - 3.3e-16 59.4 0.1 9.7e-16 57.9 0.0 1.8 1 0 0 1 1 1 1 Peptidase MA superfamily Peptidase_M61 PF05299.7 CBZ54394.1 - 0.032 14.2 0.1 0.11 12.4 0.1 1.9 1 1 0 1 1 1 0 M61 glycyl aminopeptidase PA28_beta PF02252.13 CBZ54396.1 - 2.9e-50 169.6 0.4 4.6e-50 168.9 0.3 1.2 1 0 0 1 1 1 1 Proteasome activator pa28 beta subunit DUF3166 PF11365.3 CBZ54396.1 - 1.8 9.0 5.5 25 5.4 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3166) zf-DHHC PF01529.15 CBZ54398.1 - 0.01 15.2 2.6 0.036 13.4 1.6 2.0 2 0 0 2 2 2 0 DHHC palmitoyltransferase zf-DHHC PF01529.15 CBZ54399.1 - 2.1e-39 134.6 7.0 2.1e-39 134.6 4.9 1.6 2 0 0 2 2 2 1 DHHC palmitoyltransferase Imm10 PF15562.1 CBZ54399.1 - 0.067 12.9 0.1 0.067 12.9 0.0 1.9 2 0 0 2 2 2 0 Immunity protein 10 Clathrin PF00637.15 CBZ54400.1 - 7.8e-07 28.7 0.0 0.0068 16.0 0.0 2.6 3 0 0 3 3 3 2 Region in Clathrin and VPS SIN1 PF05422.7 CBZ54400.1 - 6.9 5.0 0.0 13 4.1 0.0 1.3 1 0 0 1 1 1 0 Stress-activated map kinase interacting protein 1 (SIN1) zf-HC5HC2H_2 PF13832.1 CBZ54401.1 - 3e-18 65.8 32.2 1.6e-13 50.6 3.2 3.8 4 0 0 4 4 4 2 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 CBZ54401.1 - 1.3e-13 50.8 19.5 9.7e-10 38.4 4.9 5.0 6 0 0 6 6 6 2 PHD-like zinc-binding domain PHD PF00628.24 CBZ54401.1 - 4e-05 23.2 20.7 9.3e-05 22.0 7.8 7.3 8 0 0 8 8 8 2 PHD-finger Spot_14 PF07084.7 CBZ54401.1 - 0.27 11.1 0.2 0.83 9.4 0.1 1.8 1 0 0 1 1 1 0 Thyroid hormone-inducible hepatic protein Spot 14 PP2C PF00481.16 CBZ54402.1 - 9.2e-54 182.5 0.4 1.2e-53 182.0 0.3 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 CBZ54402.1 - 0.0015 18.0 0.0 0.0034 16.8 0.0 1.6 1 1 0 1 1 1 1 Protein phosphatase 2C AP2 PF00847.15 CBZ54403.1 - 5e-05 23.3 4.6 0.00031 20.8 0.9 3.1 3 0 0 3 3 3 1 AP2 domain Metallophos PF00149.23 CBZ54404.1 - 3.4e-37 127.7 0.4 4.5e-37 127.4 0.3 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase NT-C2 PF10358.4 CBZ54405.1 - 4.1e-07 29.5 0.1 8.3e-05 22.1 0.1 2.5 1 1 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins Rb_C PF08934.5 CBZ54405.1 - 1.3 8.5 9.6 0.076 12.6 1.9 2.4 2 0 0 2 2 2 0 Rb C-terminal domain ER_lumen_recept PF00810.13 CBZ54406.1 - 6.6e-42 143.4 4.4 6.6e-42 143.4 3.0 1.8 2 0 0 2 2 2 1 ER lumen protein retaining receptor PQ-loop PF04193.9 CBZ54406.1 - 0.022 14.2 9.4 0.032 13.7 0.2 3.4 2 1 0 2 2 2 0 PQ loop repeat PseudoU_synth_1 PF01416.15 CBZ54407.1 - 2.7e-19 69.5 0.1 1.6e-07 31.6 0.0 3.4 3 0 0 3 3 3 3 tRNA pseudouridine synthase Hydrolase PF00702.21 CBZ54408.1 - 3.9e-18 66.6 0.0 1.7e-16 61.3 0.0 2.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 CBZ54408.1 - 8.8e-15 54.3 0.8 8.8e-15 54.3 0.5 2.8 3 1 0 3 3 3 1 E1-E2 ATPase HAD PF12710.2 CBZ54408.1 - 9.9e-14 51.9 0.0 2.7e-13 50.5 0.0 1.8 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 CBZ54408.1 - 6e-08 32.5 0.0 1.6e-07 31.1 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD_2 PF13419.1 CBZ54408.1 - 0.00047 20.4 0.0 0.001 19.3 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 CBZ54408.1 - 0.015 14.8 0.0 0.028 14.0 0.0 1.3 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Adap_comp_sub PF00928.16 CBZ54409.1 - 4.5e-07 29.2 0.0 8.4e-07 28.3 0.0 1.3 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Terminase_1 PF03354.10 CBZ54409.1 - 7 4.9 0.0 9.9 4.4 0.0 1.1 1 0 0 1 1 1 0 Phage Terminase COG6 PF06419.6 CBZ54410.1 - 1.4e-26 92.8 0.0 2.1e-08 32.8 0.0 4.5 5 0 0 5 5 5 4 Conserved oligomeric complex COG6 RRM_1 PF00076.17 CBZ54412.1 - 0.00086 18.8 0.0 0.0011 18.4 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBZ54412.1 - 0.002 18.0 0.0 0.0033 17.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Proteasom_Rpn13 PF04683.8 CBZ54413.1 - 1.2e-27 95.8 0.0 2.3e-27 94.9 0.0 1.5 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor FadA PF09403.5 CBZ54413.1 - 0.36 10.8 3.5 0.52 10.3 1.7 1.7 2 0 0 2 2 2 0 Adhesion protein FadA ECH PF00378.15 CBZ54414.1 - 2.7e-28 98.7 0.0 4.1e-28 98.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family ECH_C PF13766.1 CBZ54414.1 - 3e-20 72.5 0.0 1.5e-13 50.8 0.0 2.7 3 0 0 3 3 3 2 2-enoyl-CoA Hydratase C-terminal region Kazal_2 PF07648.10 CBZ54415.1 - 3.5e-21 74.8 8.7 1.9e-08 34.1 1.5 3.5 3 0 0 3 3 3 3 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.16 CBZ54415.1 - 3.2e-19 68.6 8.4 3.4e-09 36.5 1.3 3.4 3 0 0 3 3 3 3 Kazal-type serine protease inhibitor domain Vps52 PF04129.7 CBZ54415.1 - 2.2 6.7 0.8 3.1 6.2 0.6 1.1 1 0 0 1 1 1 0 Vps52 / Sac2 family SF-assemblin PF06705.6 CBZ54416.1 - 0.57 9.2 0.3 0.87 8.6 0.2 1.1 1 0 0 1 1 1 0 SF-assemblin/beta giardin Thioredoxin PF00085.15 CBZ54417.1 - 6.3e-40 135.0 0.0 6.2e-24 83.6 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_6 PF13848.1 CBZ54417.1 - 1.1e-11 44.9 0.0 1.1e-07 31.8 0.0 4.0 3 1 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_2 PF13098.1 CBZ54417.1 - 1.4e-07 31.7 0.1 0.0001 22.4 0.0 3.7 2 2 0 2 2 2 1 Thioredoxin-like domain AhpC-TSA PF00578.16 CBZ54417.1 - 1.8e-05 24.4 0.0 0.15 11.7 0.0 2.4 2 0 0 2 2 2 2 AhpC/TSA family Thioredoxin_8 PF13905.1 CBZ54417.1 - 4.5e-05 23.5 0.0 0.1 12.7 0.0 2.7 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_7 PF13899.1 CBZ54417.1 - 0.00011 22.1 0.0 0.028 14.4 0.0 2.9 2 0 0 2 2 2 1 Thioredoxin-like Thioredoxin_9 PF14595.1 CBZ54417.1 - 0.045 13.3 0.0 7.7 6.0 0.0 2.6 2 0 0 2 2 2 0 Thioredoxin AP2 PF00847.15 CBZ54418.1 - 1.6e-08 34.5 2.9 0.0014 18.7 1.7 2.7 3 0 0 3 3 3 2 AP2 domain ACDC PF14733.1 CBZ54418.1 - 1.4e-07 31.4 0.8 3.5e-07 30.2 0.1 1.9 2 0 0 2 2 2 1 AP2-coincident C-terminal IQ PF00612.22 CBZ54419.1 - 0.0011 18.4 0.2 0.0011 18.4 0.2 2.5 2 0 0 2 2 2 1 IQ calmodulin-binding motif CPSF100_C PF13299.1 CBZ54420.1 - 5.9 7.0 11.3 0.4 10.8 2.1 2.5 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal Acetyltransf_11 PF13720.1 CBZ54421.1 - 0.077 13.2 0.1 0.11 12.7 0.1 1.2 1 0 0 1 1 1 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 Herpes_gE PF02480.11 CBZ54422.1 - 0.015 13.5 0.0 0.034 12.4 0.0 1.5 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Neur_chan_memb PF02932.11 CBZ54422.1 - 0.1 12.4 0.8 3.2 7.5 0.0 2.8 2 1 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region DUF2852 PF11014.3 CBZ54422.1 - 0.16 11.9 0.1 0.4 10.6 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2852) DUF997 PF06196.7 CBZ54422.1 - 0.2 11.1 0.0 0.34 10.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF997) DUF1049 PF06305.6 CBZ54422.1 - 0.25 10.8 1.1 0.54 9.7 0.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) SpoIIE PF07228.7 CBZ54424.1 - 5.8e-06 26.1 0.0 1.6e-05 24.7 0.0 1.8 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) GTP_EFTU PF00009.22 CBZ54425.1 - 1.1e-56 191.2 0.0 1.8e-56 190.5 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 CBZ54425.1 - 5.1e-41 138.9 0.0 9e-41 138.2 0.0 1.4 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_II PF14492.1 CBZ54425.1 - 2.4e-30 104.2 0.0 4.2e-30 103.4 0.0 1.4 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.19 CBZ54425.1 - 3.9e-21 74.7 0.0 1.2e-20 73.1 0.0 1.9 1 1 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 CBZ54425.1 - 3.6e-11 43.0 0.0 8.4e-11 41.8 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 VWA_2 PF13519.1 CBZ54426.1 - 6.3e-09 36.1 0.1 1.4e-08 35.0 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain UIM PF02809.15 CBZ54426.1 - 3.1 7.6 7.8 11 5.8 1.7 2.8 2 0 0 2 2 2 0 Ubiquitin interaction motif DnaJ PF00226.26 CBZ54427.1 - 0.074 12.8 0.2 1.6 8.5 0.0 2.5 2 0 0 2 2 2 0 DnaJ domain MIP-T3 PF10243.4 CBZ54428.1 - 0.0072 14.8 59.8 0.0085 14.6 41.4 1.0 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 RRM_1 PF00076.17 CBZ54429.1 - 2.1e-20 72.0 0.2 2.5e-11 43.0 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBZ54429.1 - 4.7e-18 64.7 0.1 1.9e-09 37.2 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBZ54429.1 - 6.8e-13 48.4 0.2 3.3e-07 30.1 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Calcipressin PF04847.7 CBZ54429.1 - 5.5e-05 22.8 0.0 0.003 17.1 0.0 2.2 2 0 0 2 2 2 1 Calcipressin RRM_3 PF08777.6 CBZ54429.1 - 0.0019 17.9 0.1 1.9 8.3 0.0 2.2 2 0 0 2 2 2 2 RNA binding motif Limkain-b1 PF11608.3 CBZ54429.1 - 0.029 14.0 0.0 0.055 13.2 0.0 1.4 1 0 0 1 1 1 0 Limkain b1 Acyltransferase PF01553.16 CBZ54431.1 - 0.004 16.5 0.0 0.0072 15.7 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase zf-RING_UBOX PF13445.1 CBZ54433.1 - 4.2e-11 42.3 3.0 8.4e-11 41.4 2.1 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.1 CBZ54433.1 - 9.1e-07 28.8 3.5 2.6e-06 27.3 2.4 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBZ54433.1 - 2.8e-06 26.9 4.9 7.6e-06 25.5 3.4 1.8 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 CBZ54433.1 - 1.6e-05 24.6 5.0 5.1e-05 23.0 3.5 2.0 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 CBZ54433.1 - 4.6e-05 22.9 5.1 0.0001 21.8 3.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 CBZ54433.1 - 8.5e-05 22.3 2.2 0.0002 21.1 1.5 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING CLTH PF10607.4 CBZ54433.1 - 0.0019 17.9 0.0 0.0049 16.5 0.0 1.6 1 1 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain zf-MIZ PF02891.15 CBZ54433.1 - 0.048 13.1 5.5 0.1 12.1 3.8 1.6 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger DUF2217 PF10265.4 CBZ54433.1 - 4.1 6.0 0.2 9.1 4.9 0.1 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) RRM_1 PF00076.17 CBZ54435.1 - 2e-12 46.5 0.0 4.1e-09 35.9 0.0 2.3 1 1 1 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBZ54435.1 - 9.6e-11 41.5 0.0 4e-10 39.5 0.0 1.9 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBZ54435.1 - 1.2e-07 31.4 0.0 2e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Josephin PF02099.12 CBZ54437.1 - 7.2e-08 32.2 0.0 0.00011 21.8 0.0 3.4 4 0 0 4 4 4 2 Josephin Citrate_synt PF00285.16 CBZ54438.1 - 1.1e-21 76.9 0.0 4.2e-20 71.8 0.0 2.7 1 1 1 2 2 2 1 Citrate synthase Ligase_CoA PF00549.14 CBZ54438.1 - 1.3e-10 41.1 0.0 4.4e-10 39.3 0.0 1.9 2 0 0 2 2 2 1 CoA-ligase CoA_binding PF02629.14 CBZ54438.1 - 2.4e-08 34.3 0.0 5.6e-08 33.1 0.0 1.7 1 0 0 1 1 1 1 CoA binding domain ATP-grasp_2 PF08442.5 CBZ54438.1 - 6.8e-06 25.6 0.0 0.00069 19.0 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain Fasciclin PF02469.17 CBZ54439.1 - 2.2e-09 37.3 0.0 4.1e-09 36.5 0.0 1.5 1 0 0 1 1 1 1 Fasciclin domain Mg_trans_NIPA PF05653.9 CBZ54440.1 - 5.7e-06 25.4 4.6 0.00018 20.6 0.9 2.2 2 0 0 2 2 2 2 Magnesium transporter NIPA EmrE PF13536.1 CBZ54440.1 - 0.025 14.7 20.6 0.015 15.5 4.6 2.8 2 0 0 2 2 2 0 Multidrug resistance efflux transporter Multi_Drug_Res PF00893.14 CBZ54440.1 - 0.14 12.6 0.9 4.4 7.8 0.3 2.7 1 1 1 2 2 2 0 Small Multidrug Resistance protein EamA PF00892.15 CBZ54440.1 - 3.7 7.5 24.7 3.8 7.5 3.8 3.5 4 0 0 4 4 4 0 EamA-like transporter family Folate_rec PF03024.9 CBZ54441.1 - 6.4e-09 35.6 0.8 1e-08 35.0 0.6 1.3 1 0 0 1 1 1 1 Folate receptor family Fz PF01392.17 CBZ54441.1 - 0.067 13.5 2.1 0.1 12.9 0.5 2.0 2 0 0 2 2 2 0 Fz domain HlyD_2 PF12700.2 CBZ54443.1 - 0.097 11.8 0.0 0.19 10.8 0.0 1.4 1 0 0 1 1 1 0 HlyD family secretion protein FANCI_S2 PF14676.1 CBZ54443.1 - 0.15 11.9 0.1 0.59 10.0 0.0 2.0 2 0 0 2 2 2 0 FANCI solenoid 2 Arm PF00514.18 CBZ54443.1 - 1.8 8.5 12.0 0.32 10.8 0.1 4.4 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat Rota_NS53 PF00981.12 CBZ54446.1 - 0.56 8.7 5.1 0.1 11.2 0.9 1.6 2 0 0 2 2 2 0 Rotavirus RNA-binding Protein 53 (NS53) DUF1289 PF06945.8 CBZ54446.1 - 0.69 9.4 9.4 3.2 7.3 0.4 3.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1289) NARP1 PF12569.3 CBZ54448.1 - 6.5e-120 401.3 24.3 9.9e-89 298.4 13.7 4.5 4 1 0 4 4 4 3 NMDA receptor-regulated protein 1 TPR_11 PF13414.1 CBZ54448.1 - 1.6e-14 53.2 7.4 0.00075 19.0 0.0 4.6 4 0 0 4 4 4 3 TPR repeat TPR_2 PF07719.12 CBZ54448.1 - 6e-14 50.7 14.2 6.4e-06 25.6 0.0 7.8 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_16 PF13432.1 CBZ54448.1 - 6.1e-11 42.6 18.9 0.00088 19.8 0.2 7.7 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_14 PF13428.1 CBZ54448.1 - 2.4e-10 40.0 12.6 0.047 14.3 0.0 9.0 9 2 1 10 10 8 3 Tetratricopeptide repeat TPR_8 PF13181.1 CBZ54448.1 - 1.2e-07 30.9 5.0 0.0074 15.9 0.0 5.5 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.1 CBZ54448.1 - 3e-07 30.1 2.5 0.1 12.8 0.0 6.7 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_12 PF13424.1 CBZ54448.1 - 3.1e-07 30.2 18.4 0.00013 21.8 0.5 6.3 5 3 2 8 8 8 2 Tetratricopeptide repeat TPR_1 PF00515.23 CBZ54448.1 - 4.1e-06 26.1 8.4 0.0084 15.6 0.0 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.1 CBZ54448.1 - 5.1e-05 22.7 0.8 0.37 10.6 0.0 4.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.1 CBZ54448.1 - 0.025 14.9 15.2 1.1 9.6 0.1 6.2 9 1 0 9 9 7 0 Tetratricopeptide repeat TPR_6 PF13174.1 CBZ54448.1 - 0.073 13.5 2.1 11 6.7 0.0 4.9 6 0 0 6 6 4 0 Tetratricopeptide repeat HemY_N PF07219.8 CBZ54448.1 - 2.2 7.8 9.4 7 6.2 2.0 2.8 1 1 1 2 2 2 0 HemY protein N-terminus LCCL PF03815.14 CBZ54449.1 - 5e-16 58.4 1.3 6.3e-15 54.9 0.0 3.1 2 1 0 2 2 2 1 LCCL domain Laminin_G_2 PF02210.19 CBZ54449.1 - 0.058 13.4 0.0 2.3 8.2 0.0 2.6 2 0 0 2 2 2 0 Laminin G domain DUF1128 PF06569.6 CBZ54449.1 - 0.1 12.3 0.1 0.22 11.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1128) RNA_pol_3_Rpc31 PF11705.3 CBZ54450.1 - 8.7e-09 35.6 8.7 1.6e-08 34.7 6.0 1.4 1 1 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 ubiquitin PF00240.18 CBZ54451.1 - 3e-21 74.5 0.3 5.1e-21 73.8 0.2 1.3 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.26 CBZ54451.1 - 7.9e-09 35.1 1.0 2e-08 33.8 0.1 2.3 2 0 0 2 2 2 1 UBA/TS-N domain Rad60-SLD PF11976.3 CBZ54451.1 - 1.5e-07 31.0 0.1 2.4e-07 30.3 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like CUE PF02845.11 CBZ54451.1 - 0.0021 17.5 0.3 0.0085 15.5 0.0 2.3 2 0 0 2 2 2 1 CUE domain Ubiquitin_2 PF14560.1 CBZ54451.1 - 0.0024 18.1 0.0 0.0058 16.8 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-like domain YukD PF08817.5 CBZ54451.1 - 0.0027 18.2 0.0 0.0068 16.9 0.0 1.7 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukD Rad60-SLD_2 PF13881.1 CBZ54451.1 - 0.075 12.9 0.1 0.17 11.7 0.0 1.6 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like BSD PF03909.12 CBZ54451.1 - 0.55 10.0 2.8 0.86 9.3 0.2 2.3 2 1 0 2 2 2 0 BSD domain Inositol_P PF00459.20 CBZ54452.1 - 2.8e-42 144.8 0.0 5.7e-42 143.8 0.0 1.5 1 0 0 1 1 1 1 Inositol monophosphatase family zf-LYAR PF08790.6 CBZ54452.1 - 2e-09 36.9 4.3 2e-09 36.9 2.9 1.9 2 0 0 2 2 2 1 LYAR-type C2HC zinc finger FBPase PF00316.15 CBZ54452.1 - 0.0082 15.0 0.0 0.026 13.3 0.0 1.7 1 1 1 2 2 2 1 Fructose-1-6-bisphosphatase DUF2201_N PF13203.1 CBZ54452.1 - 0.031 13.4 4.6 0.047 12.8 3.2 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain IBR PF01485.16 CBZ54452.1 - 0.074 12.9 1.3 0.18 11.6 0.9 1.7 1 0 0 1 1 1 0 IBR domain Ribosomal_L4 PF00573.17 CBZ54453.1 - 3.3e-43 147.3 0.0 5.2e-43 146.6 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family RabGAP-TBC PF00566.13 CBZ54454.1 - 5.3e-07 29.3 2.5 0.0065 15.9 0.1 3.1 2 1 0 2 2 2 2 Rab-GTPase-TBC domain Eapp_C PF10238.4 CBZ54455.1 - 1.5e-35 122.0 2.1 1.5e-35 122.0 1.4 2.3 2 1 0 2 2 2 1 E2F-associated phosphoprotein V-SNARE_C PF12352.3 CBZ54456.1 - 1.9e-11 43.8 0.6 4.6e-11 42.6 0.4 1.6 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.8 CBZ54456.1 - 0.00013 21.6 0.5 0.00031 20.3 0.0 1.7 2 0 0 2 2 2 1 Sec20 Proteasome PF00227.21 CBZ54459.1 - 9.5e-46 155.4 1.9 1.1e-45 155.2 1.3 1.1 1 0 0 1 1 1 1 Proteasome subunit Med4 PF10018.4 CBZ54460.1 - 0.00058 19.3 0.1 0.00058 19.3 0.1 2.2 2 0 0 2 2 2 1 Vitamin-D-receptor interacting Mediator subunit 4 NUFIP1 PF10453.4 CBZ54461.1 - 1.1e-08 34.4 0.1 2e-08 33.6 0.1 1.4 1 0 0 1 1 1 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) zf-C2H2_jaz PF12171.3 CBZ54461.1 - 0.044 13.9 0.3 0.089 12.9 0.2 1.5 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding Polysacc_synt_C PF14667.1 CBZ54462.1 - 0.075 12.8 0.4 0.075 12.8 0.3 1.7 2 0 0 2 2 2 0 Polysaccharide biosynthesis C-terminal domain IBN_N PF03810.14 CBZ54464.1 - 4.9e-12 45.5 0.0 2.6e-11 43.2 0.0 2.4 1 0 0 1 1 1 1 Importin-beta N-terminal domain Cse1 PF08506.5 CBZ54464.1 - 0.00011 20.8 0.1 0.0062 15.1 0.0 3.0 3 0 0 3 3 3 2 Cse1 MOZART1 PF12554.3 CBZ54465.1 - 1.9e-21 75.2 0.6 2.4e-21 74.9 0.4 1.1 1 0 0 1 1 1 1 Mitotic-spindle organizing gamma-tubulin ring associated MOZART2 PF12926.2 CBZ54465.1 - 0.062 12.9 0.1 0.077 12.5 0.0 1.1 1 0 0 1 1 1 0 Mitotic-spindle organizing gamma-tubulin ring associated EF-hand_1 PF00036.27 CBZ54466.1 - 5.3e-07 28.4 0.0 0.00075 18.6 0.0 2.7 2 0 0 2 2 2 2 EF hand EF-hand_5 PF13202.1 CBZ54466.1 - 3.2e-06 26.2 0.4 1.7e-05 23.9 0.0 2.2 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.1 CBZ54466.1 - 9.8e-06 25.0 0.4 0.00075 19.1 0.0 2.8 2 0 0 2 2 2 1 EF-hand domain EF-hand_8 PF13833.1 CBZ54466.1 - 1.2e-05 24.8 0.0 0.022 14.3 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_7 PF13499.1 CBZ54466.1 - 6.4e-05 23.0 0.2 0.00097 19.2 0.1 2.4 2 0 0 2 2 2 1 EF-hand domain pair NfeD PF01957.13 CBZ54466.1 - 0.045 13.8 0.6 1.3 9.1 0.1 2.4 2 0 0 2 2 2 0 NfeD-like C-terminal, partner-binding YniB PF14002.1 CBZ54466.1 - 0.046 13.1 0.1 0.47 9.9 0.0 2.1 2 0 0 2 2 2 0 YniB-like protein DUF1469 PF07332.6 CBZ54466.1 - 0.058 13.1 5.2 6.2 6.5 0.0 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF1469) DUF2976 PF11190.3 CBZ54466.1 - 0.063 12.8 1.3 0.56 9.7 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2976) DUF202 PF02656.10 CBZ54466.1 - 0.69 10.1 4.5 12 6.1 0.7 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF202) Virul_fac_BrkB PF03631.10 CBZ54466.1 - 0.79 9.0 7.0 1.4 8.2 0.3 2.8 2 1 1 3 3 3 0 Virulence factor BrkB Mlo PF03094.10 CBZ54466.1 - 0.96 7.4 4.3 2.9 5.9 0.4 2.8 2 1 0 2 2 2 0 Mlo family PrgI PF12666.2 CBZ54466.1 - 2.2 8.4 6.4 33 4.7 2.6 2.5 2 0 0 2 2 2 0 PrgI family protein Abhydrolase_5 PF12695.2 CBZ54467.1 - 3.5e-18 65.7 0.0 6.1e-18 64.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CBZ54467.1 - 9.7e-10 38.7 0.3 6.9e-08 32.6 0.0 2.8 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CBZ54467.1 - 0.0026 17.3 0.0 0.0051 16.3 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF818 PF05677.7 CBZ54467.1 - 0.0027 16.4 0.1 0.0039 15.9 0.0 1.1 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) Hydrolase_4 PF12146.3 CBZ54467.1 - 0.0077 16.0 0.2 0.029 14.2 0.0 1.9 2 0 0 2 2 2 1 Putative lysophospholipase Abhydrolase_2 PF02230.11 CBZ54467.1 - 0.15 11.4 0.0 2.4 7.5 0.0 2.4 2 1 0 2 2 2 0 Phospholipase/Carboxylesterase Cgr1 PF03879.9 CBZ54469.1 - 0.013 15.6 24.3 0.013 15.6 16.9 2.0 2 1 0 2 2 2 0 Cgr1 family TSP_1 PF00090.14 CBZ54470.1 - 1.1e-72 239.9 176.2 1.5e-10 41.0 7.3 17.7 16 1 0 16 16 16 13 Thrombospondin type 1 domain Notch PF00066.12 CBZ54470.1 - 7.1e-31 106.1 85.4 3.1e-09 36.9 10.6 7.6 5 0 0 5 5 5 4 LNR domain DUF4436 PF14494.1 CBZ54470.1 - 0.15 11.3 0.1 0.25 10.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4436) CENP-B_dimeris PF09026.5 CBZ54470.1 - 0.29 11.3 1.1 1.8 8.8 0.0 2.5 2 0 0 2 2 2 0 Centromere protein B dimerisation domain UCH PF00443.24 CBZ54471.1 - 1.4e-47 162.0 0.0 2.1e-47 161.5 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CBZ54471.1 - 1.2e-12 47.9 0.0 1.8e-07 30.9 0.0 2.2 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase DUF2185 PF09951.4 CBZ54471.1 - 0.66 9.8 0.0 1.3 8.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2185) DnaJ PF00226.26 CBZ54473.1 - 3.7e-12 45.7 0.0 1.9e-09 37.1 0.0 2.4 2 0 0 2 2 2 2 DnaJ domain zf-CSL PF05207.8 CBZ54473.1 - 0.0019 17.6 5.1 0.099 12.1 0.0 2.3 2 0 0 2 2 2 2 CSL zinc finger IF4E PF01652.13 CBZ54474.1 - 1.4e-39 135.2 0.1 1.8e-39 134.9 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Sec63 PF02889.11 CBZ54476.1 - 5.5e-188 623.7 0.0 4.3e-104 348.1 0.0 2.5 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.24 CBZ54476.1 - 2.2e-44 150.9 0.3 7.3e-29 100.4 0.1 2.9 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.26 CBZ54476.1 - 1.1e-10 41.2 0.0 4.2e-08 32.9 0.0 3.1 3 0 0 3 3 3 2 Helicase conserved C-terminal domain ResIII PF04851.10 CBZ54476.1 - 1.3e-09 38.1 0.0 7.2e-09 35.7 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 CBZ54476.1 - 0.00088 19.4 2.3 0.1 12.7 0.1 3.5 4 1 0 4 4 4 1 AAA domain AAA PF00004.24 CBZ54476.1 - 0.035 14.2 0.0 0.19 11.9 0.0 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) WD40 PF00400.27 CBZ54478.1 - 5.2e-05 22.9 0.1 0.00012 21.8 0.1 1.6 1 0 0 1 1 1 1 WD domain, G-beta repeat ATP-synt_C PF00137.16 CBZ54479.1 - 1.6e-30 104.7 31.8 3.8e-17 61.9 8.5 2.1 2 0 0 2 2 2 2 ATP synthase subunit C Tachykinin PF02202.11 CBZ54479.1 - 0.55 10.0 4.0 6.5 6.7 0.4 3.3 2 0 0 2 2 2 0 Tachykinin family PEARLI-4 PF05278.7 CBZ54480.1 - 0.38 10.0 7.3 0.037 13.3 1.4 1.9 2 0 0 2 2 2 0 Arabidopsis phospholipase-like protein (PEARLI 4) Ribosomal_S19e PF01090.14 CBZ54481.1 - 1.8e-53 179.7 0.0 2e-53 179.5 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e HTH_12 PF08461.5 CBZ54481.1 - 0.011 15.4 0.1 0.024 14.3 0.0 1.6 1 0 0 1 1 1 0 Ribonuclease R winged-helix domain Auto_anti-p27 PF06677.7 CBZ54483.1 - 1.2e-12 47.3 1.9 2.1e-12 46.5 1.3 1.3 1 0 0 1 1 1 1 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) MKT1_C PF12246.3 CBZ54484.1 - 9e-38 129.6 0.0 1.4e-37 129.0 0.0 1.2 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication MKT1_N PF12247.3 CBZ54484.1 - 2e-19 69.6 0.0 5.1e-19 68.3 0.0 1.7 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication XPG_I PF00867.13 CBZ54484.1 - 1.5e-12 47.4 0.0 3e-12 46.4 0.0 1.5 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 CBZ54484.1 - 6e-05 23.2 0.0 0.00013 22.1 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain Tubulin PF00091.20 CBZ54485.1 - 1.4e-70 237.4 0.0 2.3e-70 236.8 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 CBZ54485.1 - 1.7e-49 167.0 0.2 2.5e-49 166.4 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 CBZ54485.1 - 0.0001 22.3 0.0 0.00023 21.2 0.0 1.6 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.1 CBZ54485.1 - 0.0067 15.9 0.0 0.013 14.9 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain FeoC PF09012.5 CBZ54487.1 - 0.069 12.8 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 FeoC like transcriptional regulator Mg_trans_NIPA PF05653.9 CBZ54488.1 - 2.8e-12 46.2 7.3 3.7e-12 45.8 5.1 1.1 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.15 CBZ54488.1 - 0.00051 20.0 5.9 0.00051 20.0 4.1 3.1 3 1 0 3 3 3 1 EamA-like transporter family EmrE PF13536.1 CBZ54488.1 - 0.00086 19.4 8.1 0.00086 19.4 5.6 2.5 1 1 1 2 2 2 1 Multidrug resistance efflux transporter RRM_1 PF00076.17 CBZ54489.1 - 8.2e-16 57.4 0.0 1.9e-15 56.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBZ54489.1 - 2.8e-11 43.2 0.0 6.7e-11 42.0 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBZ54489.1 - 1.6e-06 27.8 0.0 3.6e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GIY-YIG PF01541.19 CBZ54491.1 - 1.6e-07 31.5 0.0 2.9e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 GIY-YIG catalytic domain COG4 PF08318.7 CBZ54493.1 - 9.6e-09 34.4 0.0 4.2e-08 32.3 0.0 2.2 1 1 0 1 1 1 1 COG4 transport protein Sec6 PF06046.8 CBZ54493.1 - 0.0035 15.5 0.4 1.6 6.7 0.0 3.3 4 0 0 4 4 4 2 Exocyst complex component Sec6 Sec5 PF15469.1 CBZ54493.1 - 0.079 12.6 0.5 0.27 10.9 0.4 1.9 1 0 0 1 1 1 0 Exocyst complex component Sec5 GP41 PF00517.12 CBZ54493.1 - 5.4 6.5 5.2 22 4.5 2.8 2.3 2 0 0 2 2 2 0 Retroviral envelope protein PrmA PF06325.8 CBZ54494.1 - 0.023 13.7 0.0 0.043 12.9 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) PRMT5 PF05185.11 CBZ54494.1 - 0.35 9.7 0.0 1.5 7.6 0.0 1.8 2 0 0 2 2 2 0 PRMT5 arginine-N-methyltransferase DUF3336 PF11815.3 CBZ54495.1 - 6.2e-28 97.1 0.3 1.1e-27 96.3 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.17 CBZ54495.1 - 3.6e-20 72.7 0.0 9.3e-20 71.4 0.0 1.7 1 0 0 1 1 1 1 Patatin-like phospholipase Cupin_8 PF13621.1 CBZ54496.1 - 3.7e-32 111.8 0.0 9.4e-32 110.4 0.0 1.6 1 1 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.7 CBZ54496.1 - 1e-06 28.2 0.0 0.012 14.9 0.0 2.5 2 0 0 2 2 2 2 Cupin superfamily protein ThiF PF00899.16 CBZ54497.1 - 1.4e-34 118.8 0.1 4.6e-34 117.1 0.0 1.8 1 1 0 1 1 1 1 ThiF family MoeZ_MoeB PF05237.8 CBZ54497.1 - 1.3e-19 69.5 0.0 3e-19 68.3 0.0 1.6 1 0 0 1 1 1 1 MoeZ/MoeB domain Shikimate_DH PF01488.15 CBZ54497.1 - 0.16 12.0 0.0 1.2 9.1 0.0 2.0 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Trichoplein PF13868.1 CBZ54499.1 - 1e-60 204.9 143.9 1e-60 204.9 99.7 2.1 2 0 0 2 2 2 1 Tumour suppressor, Mitostatin EphA2_TM PF14575.1 CBZ54501.1 - 0.00045 20.5 0.1 0.00076 19.8 0.1 1.4 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Ly49 PF08391.5 CBZ54501.1 - 0.0048 17.0 0.1 0.0066 16.5 0.0 1.2 1 0 0 1 1 1 1 Ly49-like protein, N-terminal region DUF1191 PF06697.7 CBZ54501.1 - 0.018 13.8 0.1 0.025 13.4 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) Cep57_CLD_2 PF14197.1 CBZ54501.1 - 0.036 13.9 0.6 0.064 13.1 0.4 1.3 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 Pox_A14 PF05767.7 CBZ54501.1 - 0.058 13.3 0.1 0.089 12.7 0.1 1.2 1 0 0 1 1 1 0 Poxvirus virion envelope protein A14 Branch_AA_trans PF05525.8 CBZ54501.1 - 0.061 11.8 0.1 0.076 11.5 0.0 1.1 1 0 0 1 1 1 0 Branched-chain amino acid transport protein Nucleoside_tran PF01733.13 CBZ54501.1 - 0.072 12.2 0.1 0.089 11.9 0.0 1.1 1 0 0 1 1 1 0 Nucleoside transporter ESSS PF10183.4 CBZ54501.1 - 0.073 13.4 0.0 0.31 11.4 0.0 1.9 2 0 0 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) SHP PF03579.8 CBZ54501.1 - 0.092 12.1 0.4 0.29 10.5 0.1 1.9 1 1 1 2 2 2 0 Small hydrophobic protein DUF4381 PF14316.1 CBZ54501.1 - 0.11 12.5 1.2 0.14 12.2 0.2 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4381) gpUL132 PF11359.3 CBZ54501.1 - 0.16 11.2 0.0 0.22 10.8 0.0 1.2 1 0 0 1 1 1 0 Glycoprotein UL132 Protocadherin PF08374.6 CBZ54501.1 - 0.16 11.5 0.0 0.18 11.4 0.0 1.1 1 0 0 1 1 1 0 Protocadherin IncA PF04156.9 CBZ54501.1 - 5.1 6.6 10.7 0.56 9.7 1.6 1.9 1 1 1 2 2 2 0 IncA protein YppG PF14179.1 CBZ54503.1 - 5.5e-08 33.3 5.7 60 4.2 0.0 7.0 7 0 0 7 7 7 0 YppG-like protein Cyclin_N PF00134.18 CBZ54503.1 - 7.1e-06 25.6 0.0 1.2e+02 2.2 0.0 6.7 7 0 0 7 7 7 0 Cyclin, N-terminal domain DIM1 PF02966.11 CBZ54503.1 - 0.0004 19.9 1.4 1.3e+02 2.0 0.0 5.8 6 0 0 6 6 6 0 Mitosis protein DIM1 Herpes_UL46 PF03387.9 CBZ54503.1 - 4.2 5.4 2.0 3.5e+02 -0.9 0.0 4.2 7 0 0 7 7 7 0 Herpesvirus UL46 protein Kinesin PF00225.18 CBZ54504.1 - 3.7e-81 272.4 0.0 5.5e-81 271.8 0.0 1.1 1 0 0 1 1 1 1 Kinesin motor domain DUF3782 PF12644.2 CBZ54504.1 - 0.16 11.7 0.3 0.73 9.6 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3782) RAP PF08373.5 CBZ54505.1 - 1.7e-11 43.7 0.0 3.5e-11 42.7 0.0 1.5 1 0 0 1 1 1 1 RAP domain Ribosomal_L18p PF00861.17 CBZ54506.1 - 0.00015 21.9 0.2 0.00027 21.1 0.1 1.3 1 0 0 1 1 1 1 Ribosomal L18p/L5e family DUF3357 PF11837.3 CBZ54507.1 - 0.0063 16.3 0.8 0.46 10.3 0.1 3.2 2 1 1 3 3 3 1 Domain of unknown function (DUF3357) WXG100 PF06013.7 CBZ54507.1 - 0.14 12.2 12.4 0.08 12.9 3.1 3.1 2 1 0 2 2 2 0 Proteins of 100 residues with WXG DUF948 PF06103.6 CBZ54507.1 - 0.8 9.5 6.0 2 8.2 0.5 3.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF4201 PF13870.1 CBZ54507.1 - 5.4 6.4 35.6 2.2 7.6 5.5 4.1 3 2 0 3 3 3 0 Domain of unknown function (DUF4201) Prominin PF05478.6 CBZ54507.1 - 6 4.2 6.9 9.7 3.5 4.8 1.3 1 0 0 1 1 1 0 Prominin DNA_pol3_beta_2 PF02767.11 CBZ54509.1 - 1.1e-08 35.1 0.2 55 3.8 0.0 7.9 8 0 0 8 8 8 0 DNA polymerase III beta subunit, central domain ATP-synt_ab PF00006.20 CBZ54509.1 - 1.1e-05 25.0 6.5 5.4 6.4 0.0 4.2 4 0 0 4 4 4 4 ATP synthase alpha/beta family, nucleotide-binding domain Pilus_CpaD PF09476.5 CBZ54509.1 - 5.3e-05 22.7 8.7 0.78 9.1 0.2 3.4 3 0 0 3 3 3 3 Pilus biogenesis CpaD protein (pilus_cpaD) Ubiquitin_3 PF14836.1 CBZ54509.1 - 0.0005 19.6 0.7 56 3.5 0.0 4.4 4 0 0 4 4 4 0 Ubiquitin-like domain DUF2233 PF09992.4 CBZ54509.1 - 0.001 19.0 1.9 55 3.7 0.0 4.2 4 0 0 4 4 4 0 Predicted periplasmic protein (DUF2233) PLAC9 PF15205.1 CBZ54509.1 - 0.0014 18.8 2.6 73 3.7 0.0 4.5 4 0 0 4 4 4 0 Placenta-specific protein 9 PrpR_N PF06506.6 CBZ54509.1 - 0.014 14.8 1.5 83 2.5 0.0 4.2 4 0 0 4 4 4 0 Propionate catabolism activator Gp_dh_C PF02800.15 CBZ54509.1 - 0.028 13.8 3.4 25 4.2 0.0 3.6 3 0 0 3 3 3 0 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain DUF4152 PF13680.1 CBZ54509.1 - 0.053 12.5 0.9 1e+02 1.7 0.0 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF4152) DUF3146 PF11344.3 CBZ54509.1 - 0.081 12.3 2.3 1.3e+02 2.0 0.0 4.1 4 0 0 4 4 4 0 Protein of unknown function (DUF3146) S19 PF06756.6 CBZ54509.1 - 2.1 8.2 7.6 1e+02 2.8 0.1 4.1 4 0 0 4 4 4 0 Chorion protein S19 C-terminal HECT PF00632.20 CBZ54509.1 - 5.1 6.1 8.4 70 2.4 0.0 3.9 4 0 0 4 4 4 0 HECT-domain (ubiquitin-transferase) UPF0640 PF15114.1 CBZ54509.1 - 7.8 6.0 8.9 72 2.9 0.1 4.2 4 0 0 4 4 4 0 Uncharacterised protein family UPF0640 2Fe-2S_Ferredox PF11591.3 CBZ54510.1 - 0.16 11.6 2.7 1.4 8.6 0.8 2.4 2 0 0 2 2 2 0 Ferredoxin chloroplastic transit peptide SHMT PF00464.14 CBZ54511.1 - 3.8e-177 588.6 0.0 4.4e-177 588.4 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase CoA_transf_3 PF02515.12 CBZ54511.1 - 0.0088 15.3 0.0 0.018 14.3 0.0 1.5 1 0 0 1 1 1 1 CoA-transferase family III A_deaminase PF00962.17 CBZ54517.1 - 4.9e-88 295.2 0.0 7.9e-88 294.5 0.0 1.3 1 0 0 1 1 1 1 Adenosine/AMP deaminase PP28 PF10252.4 CBZ54519.1 - 8.2e-21 73.8 15.3 8.2e-21 73.8 10.6 2.4 2 1 0 2 2 2 1 Casein kinase substrate phosphoprotein PP28 Daxx PF03344.10 CBZ54519.1 - 0.021 13.3 16.5 0.026 13.0 11.4 1.1 1 0 0 1 1 1 0 Daxx Family VID27 PF08553.5 CBZ54519.1 - 5.9 4.9 11.0 6.6 4.8 7.7 1.2 1 0 0 1 1 1 0 VID27 cytoplasmic protein PI3K_1B_p101 PF10486.4 CBZ54519.1 - 6.1 4.2 9.2 7.3 4.0 6.4 1.0 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit TFIIF_alpha PF05793.7 CBZ54519.1 - 7.7 4.7 24.6 12 4.0 17.1 1.4 1 1 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Abhydrolase_6 PF12697.2 CBZ54520.1 - 2.5e-28 99.5 0.7 6.3e-28 98.2 0.5 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CBZ54520.1 - 4.4e-13 49.2 0.0 3.5e-11 43.0 0.0 2.2 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CBZ54520.1 - 3.8e-09 36.4 0.0 0.00037 20.1 0.0 3.2 3 0 0 3 3 3 3 alpha/beta hydrolase fold PGAP1 PF07819.8 CBZ54520.1 - 0.0082 15.7 0.0 0.014 15.0 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_3 PF07859.8 CBZ54520.1 - 0.016 14.8 0.0 0.03 13.9 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Esterase PF00756.15 CBZ54520.1 - 0.019 14.3 0.0 0.041 13.3 0.0 1.5 1 0 0 1 1 1 0 Putative esterase DUF676 PF05057.9 CBZ54520.1 - 0.044 13.0 0.0 8 5.6 0.0 2.2 2 0 0 2 2 2 0 Putative serine esterase (DUF676) Thioesterase PF00975.15 CBZ54520.1 - 0.044 13.9 0.1 0.16 12.1 0.0 1.9 2 0 0 2 2 2 0 Thioesterase domain Lipase_3 PF01764.20 CBZ54520.1 - 0.17 11.5 0.0 0.29 10.7 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) DUF2974 PF11187.3 CBZ54520.1 - 0.17 11.2 0.0 0.26 10.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Topoisom_I PF01028.15 CBZ54521.1 - 3.4e-93 311.0 5.2 5.9e-93 310.2 3.6 1.4 1 0 0 1 1 1 1 Eukaryotic DNA topoisomerase I, catalytic core Topoisom_I_N PF02919.10 CBZ54521.1 - 1.2e-83 279.6 3.7 1.3e-83 279.5 0.1 2.5 2 0 0 2 2 2 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topo_C_assoc PF14370.1 CBZ54521.1 - 4.8e-32 109.4 0.2 1.4e-31 107.9 0.2 1.9 1 0 0 1 1 1 1 C-terminal topoisomerase domain SAG PF04092.8 CBZ54522.1 - 3.2e-12 46.9 0.4 4.3e-12 46.5 0.3 1.1 1 0 0 1 1 1 1 SRS domain TerB PF05099.8 CBZ54523.1 - 0.069 12.8 0.0 0.2 11.3 0.0 1.7 2 0 0 2 2 2 0 Tellurite resistance protein TerB Nucleo_P87 PF07267.6 CBZ54524.1 - 0.12 11.0 3.0 0.16 10.6 2.1 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 SAG PF04092.8 CBZ54525.1 - 0.12 12.7 0.0 0.17 12.2 0.0 1.2 1 0 0 1 1 1 0 SRS domain EI24 PF07264.6 CBZ54526.1 - 3.2e-17 62.6 23.9 1.2e-05 24.9 0.2 4.3 3 1 0 3 3 3 3 Etoposide-induced protein 2.4 (EI24) MS_channel PF00924.13 CBZ54527.1 - 1.6e-14 53.7 2.2 2.7e-14 52.9 1.5 1.3 1 0 0 1 1 1 1 Mechanosensitive ion channel MSP PF01716.13 CBZ54527.1 - 0.48 9.4 0.1 2 7.3 0.0 1.8 2 0 0 2 2 2 0 Manganese-stabilising protein / photosystem II polypeptide DUF3523 PF12037.3 CBZ54528.1 - 6.7e-94 313.9 26.7 6.7e-94 313.9 18.5 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF3523) AAA PF00004.24 CBZ54528.1 - 5.6e-24 84.8 0.1 2.9e-23 82.4 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 CBZ54528.1 - 3.9e-05 22.8 0.0 3.9e-05 22.8 0.0 2.0 2 1 1 3 3 3 1 Holliday junction DNA helicase ruvB N-terminus FtsK_SpoIIIE PF01580.13 CBZ54528.1 - 0.00012 21.6 2.5 0.007 15.8 0.0 2.8 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_22 PF13401.1 CBZ54528.1 - 0.00025 21.1 7.0 0.0013 18.8 0.0 3.5 2 2 0 2 2 1 1 AAA domain AAA_16 PF13191.1 CBZ54528.1 - 0.0016 18.4 0.0 0.0016 18.4 0.0 3.8 2 2 1 3 3 2 1 AAA ATPase domain AAA_17 PF13207.1 CBZ54528.1 - 0.0017 19.1 0.0 0.0017 19.1 0.0 3.1 2 2 0 2 2 1 1 AAA domain AAA_3 PF07726.6 CBZ54528.1 - 0.0027 17.3 0.0 0.0072 15.9 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 CBZ54528.1 - 0.0045 16.8 0.0 0.036 13.9 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA_25 PF13481.1 CBZ54528.1 - 0.0081 15.5 0.1 0.56 9.5 0.1 3.1 1 1 1 2 2 2 1 AAA domain AAA_5 PF07728.9 CBZ54528.1 - 0.0087 15.7 0.7 0.027 14.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 CBZ54528.1 - 0.013 14.6 0.0 0.055 12.6 0.0 2.1 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_33 PF13671.1 CBZ54528.1 - 0.017 14.9 0.0 0.017 14.9 0.0 3.1 2 2 0 2 2 1 0 AAA domain AAA_24 PF13479.1 CBZ54528.1 - 0.036 13.6 0.0 0.036 13.6 0.0 2.3 2 1 0 2 2 1 0 AAA domain RNA_helicase PF00910.17 CBZ54528.1 - 0.055 13.6 0.0 0.21 11.7 0.0 2.0 1 0 0 1 1 1 0 RNA helicase NACHT PF05729.7 CBZ54528.1 - 0.49 10.0 0.0 0.49 10.0 0.0 3.4 4 1 0 4 4 4 0 NACHT domain AAA_18 PF13238.1 CBZ54528.1 - 0.7 10.1 0.0 0.7 10.1 0.0 3.4 3 1 0 3 3 2 0 AAA domain Med15 PF09606.5 CBZ54528.1 - 2 6.4 20.2 2.7 6.1 14.0 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Aminotran_1_2 PF00155.16 CBZ54530.1 - 1.4e-27 96.6 0.0 4e-25 88.5 0.0 2.0 1 1 1 2 2 2 2 Aminotransferase class I and II Aminotran_MocR PF12897.2 CBZ54530.1 - 3.3e-06 25.9 0.0 3.1e-05 22.7 0.0 2.0 2 0 0 2 2 2 1 Alanine-glyoxylate amino-transferase Ribosomal_S8 PF00410.14 CBZ54531.1 - 2e-24 85.8 0.0 3.1e-24 85.2 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S8 MRFAP1 PF15155.1 CBZ54531.1 - 0.0042 17.4 0.0 0.0065 16.8 0.0 1.3 1 0 0 1 1 1 1 MORF4 family-associated protein1 SAG PF04092.8 CBZ54532.1 - 4.9e-43 146.4 31.7 1.2e-28 99.9 5.0 2.3 2 0 0 2 2 2 2 SRS domain SAG PF04092.8 CBZ54533.1 - 4e-43 146.7 31.2 1.1e-28 100.1 4.5 2.5 2 0 0 2 2 2 2 SRS domain SAG PF04092.8 CBZ54534.1 - 2.6e-43 147.3 30.8 1.6e-28 99.5 4.2 2.4 2 0 0 2 2 2 2 SRS domain SAG PF04092.8 CBZ54535.1 - 6.9e-41 139.5 30.5 2.7e-28 98.8 4.7 2.3 2 0 0 2 2 2 2 SRS domain Pkinase PF00069.20 CBZ54537.1 - 1.6e-45 155.2 0.0 3.7e-31 108.2 0.0 2.5 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ54537.1 - 1.7e-17 63.3 0.0 1.6e-15 56.8 0.0 2.4 2 1 0 2 2 2 2 Protein tyrosine kinase UBA_4 PF14555.1 CBZ54537.1 - 0.051 13.1 0.0 0.12 11.8 0.0 1.6 1 0 0 1 1 1 0 UBA-like domain PNP_UDP_1 PF01048.15 CBZ54540.1 - 3.3e-19 68.7 0.0 9.5e-10 37.8 0.0 2.0 1 1 1 2 2 2 2 Phosphorylase superfamily NEL PF14496.1 CBZ54540.1 - 0.039 13.2 0.0 0.065 12.5 0.0 1.3 1 0 0 1 1 1 0 C-terminal novel E3 ligase, LRR-interacting Coatomer_WDAD PF04053.9 CBZ54542.1 - 6e-127 424.0 0.0 7.9e-127 423.7 0.0 1.1 1 0 0 1 1 1 1 Coatomer WD associated region WD40 PF00400.27 CBZ54542.1 - 1.5e-37 126.1 20.1 2.6e-11 42.9 0.1 8.6 10 0 0 10 10 10 6 WD domain, G-beta repeat Nup160 PF11715.3 CBZ54542.1 - 0.061 11.4 0.1 1 7.4 0.0 2.4 3 0 0 3 3 3 0 Nucleoporin Nup120/160 TPR_2 PF07719.12 CBZ54542.1 - 2.5 8.2 6.9 1.4 8.9 0.0 3.8 5 0 0 5 5 5 0 Tetratricopeptide repeat Sugar_tr PF00083.19 CBZ54544.1 - 3.4e-25 88.5 35.9 7.8e-18 64.2 9.2 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 CBZ54544.1 - 8.8e-15 54.2 44.5 4.1e-10 38.9 14.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily RFC1 PF08519.7 CBZ54546.1 - 2e-24 86.1 0.0 3.6e-24 85.3 0.0 1.4 1 0 0 1 1 1 1 Replication factor RFC1 C terminal domain BRCT PF00533.21 CBZ54546.1 - 1e-10 41.6 0.0 2.2e-10 40.5 0.0 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain AAA PF00004.24 CBZ54546.1 - 1.3e-09 38.3 0.0 4.9e-09 36.4 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta PF06144.8 CBZ54546.1 - 1.8e-06 27.5 0.0 3.2e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase III, delta subunit Rad17 PF03215.10 CBZ54546.1 - 5.8e-06 25.2 0.0 0.04 12.6 0.0 2.9 2 1 0 2 2 2 2 Rad17 cell cycle checkpoint protein AAA_17 PF13207.1 CBZ54546.1 - 1.9e-05 25.4 0.0 8.9e-05 23.2 0.0 2.1 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 CBZ54546.1 - 5.2e-05 23.3 0.0 0.0021 18.2 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA_19 PF13245.1 CBZ54546.1 - 0.0011 18.6 0.0 0.0043 16.7 0.0 2.0 1 0 0 1 1 1 1 Part of AAA domain AAA_5 PF07728.9 CBZ54546.1 - 0.0012 18.5 0.0 0.012 15.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 CBZ54546.1 - 0.0019 18.2 0.0 0.0086 16.0 0.0 2.2 1 0 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.1 CBZ54546.1 - 0.0019 18.4 0.0 0.009 16.3 0.0 2.2 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 CBZ54546.1 - 0.012 14.7 0.0 0.13 11.2 0.0 2.1 2 0 0 2 2 2 0 Holliday junction DNA helicase ruvB N-terminus GCC2_GCC3 PF07699.8 CBZ54547.1 - 3.3e-06 26.5 338.6 2.2e-05 23.9 2.4 31.8 25 8 7 32 32 32 20 GCC2 and GCC3 NHL PF01436.16 CBZ54547.1 - 1.8e-05 24.4 3.9 0.00015 21.5 0.0 3.8 4 0 0 4 4 4 1 NHL repeat ORMDL PF04061.9 CBZ54547.1 - 3.9 7.0 0.0 7.1 6.1 0.0 1.3 1 0 0 1 1 1 0 ORMDL family PAN_4 PF14295.1 CBZ54548.1 - 1.1e-81 268.4 123.1 8.5e-10 38.1 1.2 17.4 17 0 0 17 17 17 16 PAN domain PAN_1 PF00024.21 CBZ54548.1 - 3.4e-75 247.8 92.0 2.4e-07 30.3 1.7 16.4 16 0 0 16 16 16 16 PAN domain PAN_2 PF08276.6 CBZ54548.1 - 0.23 11.3 110.7 0.11 12.3 0.4 15.8 16 0 0 16 16 16 0 PAN-like domain PAN_4 PF14295.1 CBZ54549.1 - 1.1e-94 309.9 139.6 2.1e-09 36.9 1.9 18.4 18 0 0 18 18 18 18 PAN domain PAN_1 PF00024.21 CBZ54549.1 - 6.1e-84 275.8 107.5 2.4e-07 30.3 1.7 17.8 17 1 0 18 18 18 17 PAN domain PAN_2 PF08276.6 CBZ54549.1 - 0.62 9.9 126.2 0.071 12.9 1.0 17.1 17 0 0 17 17 17 0 PAN-like domain CwfJ_C_1 PF04677.10 CBZ54551.1 - 1.3e-14 53.8 0.0 2.1e-14 53.2 0.0 1.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.9 CBZ54551.1 - 4.5e-14 52.7 0.3 2.3e-13 50.4 0.0 2.3 2 0 0 2 2 2 1 Protein similar to CwfJ C-terminus 2 Pkinase PF00069.20 CBZ54553.1 - 4.7e-11 42.3 0.0 7.6e-11 41.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 CBZ54553.1 - 0.059 13.1 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family PAN_4 PF14295.1 CBZ54555.1 - 2e-90 296.3 96.1 6e-10 38.6 0.6 13.7 13 0 0 13 13 13 13 PAN domain PAN_1 PF00024.21 CBZ54555.1 - 3.9e-72 238.0 71.0 1.5e-06 27.8 1.1 13.5 12 2 1 13 13 13 13 PAN domain HI0933_like PF03486.9 CBZ54556.1 - 0.043 12.2 0.1 0.067 11.6 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein LSM PF01423.17 CBZ54559.1 - 5.2e-06 25.9 0.1 1.4e-05 24.5 0.1 1.7 2 0 0 2 2 2 1 LSM domain UQ_con PF00179.21 CBZ54560.1 - 3.6e-43 146.3 0.0 8.6e-43 145.1 0.0 1.6 2 0 0 2 2 2 1 Ubiquitin-conjugating enzyme UBA PF00627.26 CBZ54560.1 - 5e-09 35.7 0.1 1.6e-08 34.1 0.1 1.9 1 0 0 1 1 1 1 UBA/TS-N domain Prok-E2_B PF14461.1 CBZ54560.1 - 1.8e-05 24.4 0.0 5.2e-05 23.0 0.0 1.7 2 0 0 2 2 2 1 Prokaryotic E2 family B RWD PF05773.17 CBZ54560.1 - 0.017 15.0 0.0 0.03 14.1 0.0 1.5 1 0 0 1 1 1 0 RWD domain UBA_4 PF14555.1 CBZ54560.1 - 0.14 11.7 0.1 0.27 10.8 0.1 1.5 1 0 0 1 1 1 0 UBA-like domain Myosin_head PF00063.16 CBZ54561.1 - 5e-165 550.3 0.1 8.6e-165 549.5 0.1 1.3 1 1 0 1 1 1 1 Myosin head (motor domain) Zeta_toxin PF06414.7 CBZ54561.1 - 0.014 14.4 0.1 0.033 13.2 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin ATP-synt_ab PF00006.20 CBZ54561.1 - 0.015 14.8 0.0 0.018 14.5 0.0 1.4 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_22 PF13401.1 CBZ54561.1 - 0.033 14.3 0.0 0.1 12.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 CBZ54561.1 - 0.07 12.8 0.2 0.25 11.1 0.0 2.0 2 0 0 2 2 2 0 Part of AAA domain ABC_tran PF00005.22 CBZ54561.1 - 0.076 13.3 0.0 0.26 11.5 0.0 2.0 2 0 0 2 2 2 0 ABC transporter T2SE PF00437.15 CBZ54561.1 - 0.078 11.8 0.0 0.2 10.5 0.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_16 PF13191.1 CBZ54561.1 - 0.1 12.5 0.0 0.29 11.0 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain PRK PF00485.13 CBZ54561.1 - 0.13 11.8 0.1 0.48 9.9 0.1 1.9 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family Fumble PF03630.9 CBZ54562.1 - 1.7e-36 125.7 0.0 1.6e-22 79.8 0.0 2.7 2 1 0 2 2 2 2 Fumble Calreticulin PF00262.13 CBZ54562.1 - 0.1 11.2 0.7 0.17 10.4 0.5 1.2 1 0 0 1 1 1 0 Calreticulin family Hid1 PF12722.2 CBZ54563.1 - 9.7e-122 407.4 0.0 1.1e-96 324.5 0.0 2.8 1 1 1 2 2 2 2 High-temperature-induced dauer-formation protein Dymeclin PF09742.4 CBZ54563.1 - 8.1e-80 268.8 0.0 5e-77 259.5 0.0 2.2 2 0 0 2 2 2 2 Dyggve-Melchior-Clausen syndrome protein MORN PF02493.15 CBZ54564.1 - 3e-23 80.0 39.4 5e-06 25.9 1.1 6.8 6 0 0 6 6 6 6 MORN repeat eIF-5_eIF-2B PF01873.12 CBZ54565.1 - 1.8e-37 127.7 0.0 2.9e-37 127.1 0.0 1.3 1 1 0 1 1 1 1 Domain found in IF2B/IF5 NPIP PF06409.6 CBZ54565.1 - 0.034 12.8 1.2 0.061 12.0 0.8 1.3 1 0 0 1 1 1 0 Nuclear pore complex interacting protein (NPIP) GCC2_GCC3 PF07699.8 CBZ54565.1 - 0.17 11.5 4.9 2.3 7.8 0.6 2.4 1 1 1 2 2 2 0 GCC2 and GCC3 zf-RanBP PF00641.13 CBZ54565.1 - 1.1 8.4 5.6 1.8 7.7 0.3 2.6 3 0 0 3 3 3 0 Zn-finger in Ran binding protein and others PHD PF00628.24 CBZ54566.1 - 1.9e-10 40.2 32.9 3.7e-06 26.5 6.7 3.5 3 1 1 4 4 4 2 PHD-finger Trm112p PF03966.11 CBZ54566.1 - 0.048 14.0 1.3 0.15 12.4 0.9 1.9 1 1 0 1 1 1 0 Trm112p-like protein DUF1517 PF07466.6 CBZ54566.1 - 0.44 9.4 9.9 0.74 8.7 6.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) SAG PF04092.8 CBZ54569.1 - 4.6e-14 52.8 6.4 8.8e-14 51.9 4.5 1.5 1 1 0 1 1 1 1 SRS domain FixG_C PF11614.3 CBZ54569.1 - 0.014 15.5 0.2 0.024 14.7 0.1 1.4 1 0 0 1 1 1 0 IG-like fold at C-terminal of FixG, putative oxidoreductase zf-NADH-PPase PF09297.6 CBZ54569.1 - 0.19 11.2 0.9 0.32 10.5 0.6 1.4 1 0 0 1 1 1 0 NADH pyrophosphatase zinc ribbon domain SAG PF04092.8 CBZ54570.1 - 2.3e-11 44.1 5.9 4.3e-11 43.2 4.1 1.5 1 1 0 1 1 1 1 SRS domain DUF2062 PF09835.4 CBZ54570.1 - 0.19 11.3 0.3 0.19 11.3 0.2 1.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2062) AAA PF00004.24 CBZ54571.1 - 4.7e-74 246.8 0.0 1.3e-44 151.6 0.0 4.3 3 1 0 3 3 3 3 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 CBZ54571.1 - 2.8e-11 43.7 0.4 6.6e-06 26.2 0.2 3.6 2 1 0 2 2 2 2 AAA ATPase domain RuvB_N PF05496.7 CBZ54571.1 - 4.8e-10 38.8 0.0 0.0013 17.7 0.0 3.1 3 0 0 3 3 3 2 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 CBZ54571.1 - 5.6e-09 35.8 0.1 0.0027 17.4 0.0 3.4 3 1 0 3 3 2 2 AAA domain (dynein-related subfamily) TIP49 PF06068.8 CBZ54571.1 - 2.6e-08 33.0 0.2 0.00059 18.6 0.0 2.5 3 0 0 3 3 3 2 TIP49 C-terminus AAA_22 PF13401.1 CBZ54571.1 - 4e-08 33.4 0.0 0.0011 19.1 0.0 4.2 4 1 0 4 4 3 1 AAA domain AAA_17 PF13207.1 CBZ54571.1 - 8.1e-08 33.1 0.0 0.00011 23.0 0.0 3.0 3 0 0 3 3 2 1 AAA domain AAA_2 PF07724.9 CBZ54571.1 - 1e-07 32.0 0.0 0.052 13.4 0.0 3.4 3 0 0 3 3 3 2 AAA domain (Cdc48 subfamily) Zeta_toxin PF06414.7 CBZ54571.1 - 1e-06 28.0 0.0 0.0053 15.8 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin IstB_IS21 PF01695.12 CBZ54571.1 - 2.4e-06 27.0 0.0 0.0039 16.6 0.0 2.3 2 0 0 2 2 2 2 IstB-like ATP binding protein Mg_chelatase PF01078.16 CBZ54571.1 - 3.4e-06 26.3 0.3 0.16 11.1 0.0 3.1 3 0 0 3 3 3 2 Magnesium chelatase, subunit ChlI AAA_33 PF13671.1 CBZ54571.1 - 3.7e-06 26.8 0.0 0.0023 17.8 0.0 3.0 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 CBZ54571.1 - 3.6e-05 23.8 0.0 0.19 11.8 0.0 2.7 3 0 0 3 3 2 2 RNA helicase AAA_19 PF13245.1 CBZ54571.1 - 5e-05 22.9 0.8 0.018 14.8 0.0 3.7 3 0 0 3 3 3 1 Part of AAA domain Sigma54_activ_2 PF14532.1 CBZ54571.1 - 6.6e-05 22.9 0.0 0.16 12.0 0.0 2.6 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_14 PF13173.1 CBZ54571.1 - 0.00011 22.0 0.0 0.23 11.3 0.0 3.2 3 0 0 3 3 3 1 AAA domain NACHT PF05729.7 CBZ54571.1 - 0.00039 20.1 0.0 0.13 11.8 0.0 3.3 4 0 0 4 4 3 1 NACHT domain AAA_25 PF13481.1 CBZ54571.1 - 0.0004 19.8 0.3 1 8.7 0.0 4.1 3 1 0 4 4 4 1 AAA domain AAA_28 PF13521.1 CBZ54571.1 - 0.00057 19.8 0.8 0.13 12.1 0.0 3.5 4 0 0 4 4 3 1 AAA domain AAA_3 PF07726.6 CBZ54571.1 - 0.0014 18.2 0.0 1.9 8.1 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.1 CBZ54571.1 - 0.0018 17.9 0.1 0.3 10.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain Arch_ATPase PF01637.13 CBZ54571.1 - 0.0023 17.6 0.0 0.63 9.7 0.0 3.1 2 1 1 3 3 3 1 Archaeal ATPase AAA_18 PF13238.1 CBZ54571.1 - 0.0026 18.0 0.0 0.009 16.3 0.0 1.9 2 0 0 2 2 1 1 AAA domain ABC_tran PF00005.22 CBZ54571.1 - 0.015 15.6 0.0 1.2 9.4 0.0 2.6 2 0 0 2 2 2 0 ABC transporter Bac_DnaA PF00308.13 CBZ54571.1 - 0.016 14.8 0.0 0.27 10.8 0.0 2.6 3 0 0 3 3 3 0 Bacterial dnaA protein Sigma54_activat PF00158.21 CBZ54571.1 - 0.016 14.6 0.0 6.3 6.2 0.0 2.9 3 0 0 3 3 3 0 Sigma-54 interaction domain UPF0079 PF02367.12 CBZ54571.1 - 0.027 14.0 0.0 0.7 9.5 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 DUF815 PF05673.8 CBZ54571.1 - 0.028 13.3 0.0 6.4 5.6 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) NB-ARC PF00931.17 CBZ54571.1 - 0.039 12.8 0.0 1.6 7.4 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain Rad17 PF03215.10 CBZ54571.1 - 0.063 11.9 0.0 0.47 9.0 0.0 1.9 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein NTPase_1 PF03266.10 CBZ54571.1 - 0.066 12.9 0.1 6.3 6.4 0.0 2.9 2 1 0 3 3 3 0 NTPase KaiC PF06745.8 CBZ54571.1 - 0.071 12.2 0.0 11 5.0 0.0 2.6 3 0 0 3 3 3 0 KaiC AFG1_ATPase PF03969.11 CBZ54571.1 - 0.082 11.7 0.0 5.2 5.7 0.0 2.4 2 0 0 2 2 2 0 AFG1-like ATPase Zot PF05707.7 CBZ54571.1 - 0.089 12.2 0.0 9 5.7 0.0 2.7 2 0 0 2 2 2 0 Zonular occludens toxin (Zot) Parvo_NS1 PF01057.12 CBZ54571.1 - 0.097 11.5 0.0 3.7 6.3 0.0 2.2 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 PhoH PF02562.11 CBZ54571.1 - 0.12 11.6 0.0 2.6 7.2 0.0 2.2 2 0 0 2 2 2 0 PhoH-like protein Viral_helicase1 PF01443.13 CBZ54571.1 - 0.16 11.4 0.0 9.9 5.6 0.0 2.5 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase Tom5 PF10642.4 CBZ54571.1 - 1.6 8.4 4.4 2.2 8.0 1.2 2.4 2 0 0 2 2 2 0 Mitochondrial import receptor subunit or translocase DS PF01916.12 CBZ54572.1 - 2.7e-127 424.0 0.0 3.2e-127 423.7 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase Formyl_trans_N PF00551.14 CBZ54573.1 - 1.2e-24 86.8 0.0 2.6e-24 85.7 0.0 1.5 1 0 0 1 1 1 1 Formyl transferase Formyl_trans_C PF02911.13 CBZ54573.1 - 8.2e-10 38.6 0.0 0.0003 20.8 0.0 2.5 2 0 0 2 2 2 2 Formyl transferase, C-terminal domain Mito_carr PF00153.22 CBZ54574.1 - 9.4e-37 124.6 1.0 1.2e-12 47.3 0.0 5.0 4 1 0 4 4 4 4 Mitochondrial carrier protein DUF1682 PF07946.9 CBZ54575.1 - 1.8e-66 224.1 0.3 2.2e-66 223.8 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) Ribosomal_60s PF00428.14 CBZ54575.1 - 0.00018 21.8 1.4 0.082 13.3 0.0 2.9 2 0 0 2 2 2 2 60s Acidic ribosomal protein GLE1 PF07817.8 CBZ54575.1 - 0.11 11.4 0.0 0.11 11.4 0.0 2.1 2 0 0 2 2 2 0 GLE1-like protein Flavin_Reduct PF01613.13 CBZ54575.1 - 0.25 11.2 3.7 0.99 9.2 0.4 2.3 2 0 0 2 2 2 0 Flavin reductase like domain DUF347 PF03988.7 CBZ54575.1 - 0.6 10.0 2.5 11 6.0 0.1 2.5 2 0 0 2 2 2 0 Repeat of Unknown Function (DUF347) IncFII_repA PF02387.10 CBZ54575.1 - 8.1 5.5 12.3 13 4.8 8.5 1.2 1 0 0 1 1 1 0 IncFII RepA protein family Peptidase_M16_C PF05193.16 CBZ54577.1 - 1.4e-24 86.7 0.0 1.3e-14 54.3 0.0 2.8 2 0 0 2 2 2 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 CBZ54577.1 - 1.9e-22 79.5 2.0 7.9e-21 74.3 0.3 3.2 2 1 0 2 2 2 1 Insulinase (Peptidase family M16) HpaB_N PF11794.3 CBZ54577.1 - 0.059 12.7 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal FBPase PF00316.15 CBZ54579.1 - 3.9e-26 91.6 0.0 4.4e-26 91.4 0.0 1.0 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase HPIP PF15226.1 CBZ54579.1 - 0.048 13.7 0.1 0.07 13.1 0.1 1.3 1 0 0 1 1 1 0 HCF-1 beta-propeller-interacting protein family FBPase PF00316.15 CBZ54580.1 - 1.1e-23 83.5 0.0 1.4e-23 83.3 0.0 1.0 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase RNase_P_Rpp14 PF01900.14 CBZ54581.1 - 3.6e-06 26.8 0.0 5.6e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 Rpp14/Pop5 family Rpr2 PF04032.11 CBZ54582.1 - 8.2e-12 44.8 0.5 1.3e-10 40.9 0.1 2.4 2 0 0 2 2 2 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain SMAP PF15477.1 CBZ54584.1 - 2.5e-17 62.9 1.6 2.5e-17 62.9 1.1 3.9 4 1 0 4 4 4 1 Small acidic protein family FHA PF00498.21 CBZ54584.1 - 3.7e-08 33.3 0.2 2.9e-07 30.4 0.1 2.1 1 1 0 1 1 1 1 FHA domain DUF1777 PF08648.7 CBZ54584.1 - 0.022 14.4 52.9 0.015 15.0 15.3 3.4 3 1 0 3 3 3 0 Protein of unknown function (DUF1777) EAP30 PF04157.11 CBZ54584.1 - 0.065 12.3 1.7 0.11 11.6 1.2 1.3 1 0 0 1 1 1 0 EAP30/Vps36 family Pkinase PF00069.20 CBZ54585.1 - 1.7e-69 233.8 0.0 2.2e-69 233.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ54585.1 - 6.8e-33 113.8 0.0 8.8e-33 113.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBZ54585.1 - 3e-08 32.9 0.0 2.2e-06 26.8 0.0 2.7 2 1 0 2 2 2 1 Kinase-like Kdo PF06293.9 CBZ54585.1 - 0.0018 17.3 0.0 0.0035 16.4 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CBZ54585.1 - 0.0038 16.9 0.0 0.022 14.4 0.0 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 CBZ54585.1 - 0.041 13.2 0.0 0.079 12.2 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Cytokin-bind PF09265.5 CBZ54585.1 - 0.05 12.7 0.0 0.11 11.6 0.0 1.6 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding EcKinase PF02958.15 CBZ54585.1 - 0.088 11.9 0.0 0.15 11.2 0.0 1.3 1 0 0 1 1 1 0 Ecdysteroid kinase Peptidase_S8 PF00082.17 CBZ54586.1 - 2.2e-48 164.8 0.9 3.4e-48 164.2 0.6 1.3 1 0 0 1 1 1 1 Subtilase family EGF_3 PF12947.2 CBZ54586.1 - 5.3e-13 48.6 43.8 7.6e-05 22.5 5.2 5.2 5 0 0 5 5 5 4 EGF domain EGF_CA PF07645.10 CBZ54586.1 - 6.1e-13 48.5 17.6 4.4e-08 32.9 3.7 5.0 4 1 1 5 5 5 2 Calcium-binding EGF domain cEGF PF12662.2 CBZ54586.1 - 2.1e-12 46.4 23.7 2.6e-06 26.9 0.8 4.6 4 0 0 4 4 4 3 Complement Clr-like EGF-like FXa_inhibition PF14670.1 CBZ54586.1 - 0.00087 19.3 43.6 0.0083 16.2 3.7 4.8 4 0 0 4 4 4 2 Coagulation Factor Xa inhibitory site EGF PF00008.22 CBZ54586.1 - 1.3 9.1 40.4 0.19 11.7 3.0 5.6 5 0 0 5 5 5 0 EGF-like domain EB PF01683.13 CBZ54586.1 - 3.8 7.6 40.5 2 8.5 3.3 4.5 2 2 2 4 4 4 0 EB module TPR_10 PF13374.1 CBZ54587.1 - 0.0011 18.8 0.0 0.0034 17.2 0.0 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_12 PF13424.1 CBZ54587.1 - 0.0031 17.4 0.0 0.0084 16.0 0.0 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat MPC PF03650.8 CBZ54588.1 - 2.6e-36 124.1 0.3 7.9e-36 122.6 0.1 1.8 2 1 0 2 2 2 1 Uncharacterised protein family (UPF0041) Basic PF01586.11 CBZ54589.1 - 0.029 15.0 0.2 0.058 14.1 0.1 1.5 1 0 0 1 1 1 0 Myogenic Basic domain DUF581 PF04570.9 CBZ54589.1 - 0.21 10.9 1.5 0.26 10.5 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF581) Lactamase_B_2 PF12706.2 CBZ54590.1 - 8.3e-33 113.5 0.2 6.3e-32 110.7 0.2 2.1 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_4 PF13691.1 CBZ54590.1 - 1.8e-07 30.5 0.0 5.6e-07 28.9 0.0 1.8 1 0 0 1 1 1 1 tRNase Z endonuclease RHH_1 PF01402.16 CBZ54590.1 - 0.17 11.8 0.7 0.39 10.6 0.5 1.6 1 0 0 1 1 1 0 Ribbon-helix-helix protein, copG family zf-CCCH PF00642.19 CBZ54591.1 - 2.3e-11 43.1 6.9 8.8e-07 28.4 0.6 2.6 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 CBZ54591.1 - 0.0087 16.0 6.7 1 9.4 0.4 3.0 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type Dynein_heavy PF03028.10 CBZ54592.1 - 6.7e-193 642.5 0.0 6.1e-191 636.0 0.0 3.0 3 0 0 3 3 3 1 Dynein heavy chain and region D6 of dynein motor DHC_N2 PF08393.8 CBZ54592.1 - 1.7e-118 395.6 11.4 1.7e-118 395.6 7.9 2.5 2 0 0 2 2 2 1 Dynein heavy chain, N-terminal region 2 DHC_N1 PF08385.7 CBZ54592.1 - 7.3e-100 335.0 13.9 2.1e-99 333.4 2.2 3.6 2 1 1 3 3 3 2 Dynein heavy chain, N-terminal region 1 AAA_6 PF12774.2 CBZ54592.1 - 1.3e-79 267.0 0.1 9.8e-64 215.0 0.0 2.9 2 1 1 3 3 3 2 Hydrolytic ATP binding site of dynein motor region D1 AAA_8 PF12780.2 CBZ54592.1 - 3.1e-61 206.6 0.0 8.3e-61 205.2 0.0 1.8 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_9 PF12781.2 CBZ54592.1 - 1.5e-55 187.5 0.2 3.1e-55 186.5 0.1 1.6 1 0 0 1 1 1 1 ATP-binding dynein motor region D5 MT PF12777.2 CBZ54592.1 - 4.4e-53 180.2 10.7 8.4e-53 179.3 7.4 1.5 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_7 PF12775.2 CBZ54592.1 - 1.9e-45 155.0 0.0 3.5e-45 154.1 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region D3 AAA_5 PF07728.9 CBZ54592.1 - 1.1e-16 60.8 0.0 4.5e-06 26.4 0.0 4.4 4 0 0 4 4 4 3 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 CBZ54592.1 - 0.0072 16.4 0.0 0.51 10.4 0.0 4.0 3 0 0 3 3 3 1 AAA domain AflR PF08493.5 CBZ54592.1 - 0.83 8.6 0.0 1.8 7.4 0.0 1.5 1 0 0 1 1 1 0 Aflatoxin regulatory protein KH_1 PF00013.24 CBZ54593.1 - 1.9e-23 81.8 0.0 8.9e-08 31.6 0.0 4.2 4 0 0 4 4 4 4 KH domain KH_3 PF13014.1 CBZ54593.1 - 2.5e-11 42.9 0.1 0.012 15.2 0.0 4.4 4 0 0 4 4 4 3 KH domain KH_2 PF07650.12 CBZ54593.1 - 0.00012 21.5 0.0 9.5 5.8 0.0 4.2 4 0 0 4 4 4 2 KH domain Peptidase_S8 PF00082.17 CBZ54594.1 - 1.3e-52 178.7 6.4 2.4e-52 177.8 4.4 1.5 1 0 0 1 1 1 1 Subtilase family Methyltransf_16 PF10294.4 CBZ54595.1 - 2.9e-17 62.6 0.0 2.3e-05 23.9 0.0 3.3 1 1 2 3 3 3 3 Putative methyltransferase Methyltransf_26 PF13659.1 CBZ54595.1 - 0.00054 19.9 0.1 0.0013 18.7 0.1 1.7 1 0 0 1 1 1 1 Methyltransferase domain SAG PF04092.8 CBZ54596.1 - 2.1e-15 57.1 15.6 9.9e-13 48.5 0.2 2.7 2 1 0 2 2 2 2 SRS domain s48_45 PF07422.8 CBZ54596.1 - 0.00071 19.6 0.1 0.31 11.1 0.0 2.5 2 1 0 2 2 2 2 Sexual stage antigen s48/45 domain Elicitin PF00964.12 CBZ54596.1 - 0.021 14.7 1.1 0.021 14.7 0.8 2.5 2 1 0 2 2 2 0 Elicitin SAG PF04092.8 CBZ54597.1 - 1.5e-19 70.6 12.5 2.1e-15 57.2 0.5 2.2 2 0 0 2 2 2 2 SRS domain TFIIS_C PF01096.13 CBZ54597.1 - 0.062 12.9 0.3 0.56 9.8 0.0 2.6 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) Elicitin PF00964.12 CBZ54597.1 - 1.1 9.3 13.9 0.07 13.0 1.2 3.4 4 0 0 4 4 4 0 Elicitin SAG PF04092.8 CBZ54598.1 - 6.2e-15 55.6 14.3 4.4e-12 46.4 5.6 2.3 2 0 0 2 2 2 2 SRS domain s48_45 PF07422.8 CBZ54598.1 - 0.036 14.1 1.8 0.039 14.0 0.2 1.8 2 0 0 2 2 2 0 Sexual stage antigen s48/45 domain SAG PF04092.8 CBZ54599.1 - 3.7e-19 69.3 8.5 1.6e-16 60.8 1.7 2.3 2 0 0 2 2 2 2 SRS domain SAG PF04092.8 CBZ54600.1 - 2.5e-14 53.7 20.4 3.5e-12 46.7 4.3 2.6 2 1 0 2 2 2 2 SRS domain s48_45 PF07422.8 CBZ54600.1 - 0.0015 18.5 3.8 0.086 12.9 0.2 2.7 2 1 0 2 2 2 2 Sexual stage antigen s48/45 domain SAG PF04092.8 CBZ54601.1 - 5.4e-17 62.3 21.0 9.7e-13 48.6 5.0 2.4 2 0 0 2 2 2 2 SRS domain s48_45 PF07422.8 CBZ54601.1 - 0.00029 20.9 2.1 0.088 12.9 0.2 2.6 2 0 0 2 2 2 2 Sexual stage antigen s48/45 domain GTP_EFTU PF00009.22 CBZ54602.1 - 8.3e-38 129.7 0.0 1.4e-37 128.9 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain eIF2_C PF09173.6 CBZ54602.1 - 3.3e-34 116.7 0.0 6.6e-34 115.8 0.0 1.5 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU_D2 PF03144.20 CBZ54602.1 - 6.2e-11 42.2 1.8 1.6e-10 40.9 0.4 2.4 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 CBZ54602.1 - 0.021 14.8 0.0 0.039 13.8 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase IBR PF01485.16 CBZ54603.1 - 5.4e-19 67.8 31.0 1.4e-10 40.8 8.3 4.1 3 1 0 3 3 3 2 IBR domain zf-C3HC4_2 PF13923.1 CBZ54603.1 - 0.0012 18.7 0.2 0.0012 18.7 0.2 4.1 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CBZ54603.1 - 0.0027 17.4 25.6 0.023 14.5 0.1 3.6 3 0 0 3 3 3 2 Ring finger domain zf-C3HC4_4 PF15227.1 CBZ54603.1 - 6.8 6.6 25.1 1.2 9.1 4.8 4.3 4 1 0 4 4 4 0 zinc finger of C3HC4-type, RING MIF4G PF02854.14 CBZ54604.1 - 0.0032 16.9 0.0 0.17 11.2 0.0 2.6 2 0 0 2 2 2 2 MIF4G domain Fer2 PF00111.22 CBZ54605.1 - 2.1e-08 33.7 1.4 3.6e-08 33.0 1.0 1.4 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Prenylcys_lyase PF07156.9 CBZ54606.1 - 5.6e-24 84.7 0.0 2e-16 59.8 0.0 2.5 2 1 0 2 2 2 2 Prenylcysteine lyase NAD_binding_8 PF13450.1 CBZ54606.1 - 5.6e-06 26.2 0.8 4.6e-05 23.3 0.5 2.5 1 1 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 CBZ54606.1 - 0.015 14.4 0.3 0.053 12.5 0.2 1.8 1 1 0 1 1 1 0 Flavin containing amine oxidoreductase DAO PF01266.19 CBZ54606.1 - 0.025 13.5 5.2 0.39 9.5 3.2 2.3 1 1 1 2 2 2 0 FAD dependent oxidoreductase BT1 PF03092.11 CBZ54607.1 - 4.6e-55 187.0 18.7 5.9e-55 186.7 13.0 1.0 1 0 0 1 1 1 1 BT1 family DUF775 PF05603.7 CBZ54608.1 - 1.3e-26 93.3 0.0 2.3e-25 89.2 0.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF775) Glycolytic PF00274.14 CBZ54609.1 - 8e-169 560.5 0.0 9e-169 560.3 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-I HrpB1_HrpK PF09613.5 CBZ54609.1 - 0.088 12.2 0.0 0.19 11.2 0.0 1.5 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB1_HrpK) Glycolytic PF00274.14 CBZ54610.1 - 1.3e-163 543.3 0.0 1.5e-163 543.1 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-I HrpB1_HrpK PF09613.5 CBZ54610.1 - 0.021 14.3 0.2 0.042 13.3 0.2 1.4 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB1_HrpK) Trp_halogenase PF04820.9 CBZ54610.1 - 0.096 11.2 0.0 0.17 10.4 0.0 1.3 1 0 0 1 1 1 0 Tryptophan halogenase P5CR_dimer PF14748.1 CBZ54611.1 - 6.4e-37 125.8 0.1 1.1e-36 125.1 0.1 1.4 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.12 CBZ54611.1 - 1.9e-13 50.6 0.2 3.3e-13 49.8 0.1 1.4 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.10 CBZ54611.1 - 0.00013 21.8 0.1 0.00041 20.2 0.1 1.8 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_Gly3P_dh_N PF01210.18 CBZ54611.1 - 0.00027 20.7 0.0 0.36 10.5 0.0 2.5 2 0 0 2 2 2 2 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ApbA PF02558.11 CBZ54611.1 - 0.041 13.3 0.0 0.068 12.6 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Shikimate_DH PF01488.15 CBZ54611.1 - 0.044 13.8 0.1 0.082 13.0 0.1 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase GFO_IDH_MocA PF01408.17 CBZ54611.1 - 0.052 14.0 0.1 0.12 12.9 0.0 1.6 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold Rep_fac-A_C PF08646.5 CBZ54612.1 - 1.4e-30 105.9 1.7 7.6e-30 103.5 0.6 2.1 2 0 0 2 2 2 1 Replication factor-A C terminal domain tRNA_anti-codon PF01336.20 CBZ54612.1 - 4.2e-13 48.9 0.0 1.3e-09 37.7 0.0 2.6 2 0 0 2 2 2 2 OB-fold nucleic acid binding domain tRNA_anti_2 PF13742.1 CBZ54612.1 - 0.015 15.1 0.0 0.043 13.6 0.0 1.7 2 0 0 2 2 2 0 OB-fold nucleic acid binding domain DUF4539 PF15072.1 CBZ54612.1 - 0.067 12.8 0.0 4.5 7.0 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4539) Ribosomal_L37ae PF01780.14 CBZ54612.1 - 0.39 10.6 1.7 0.75 9.7 1.2 1.3 1 0 0 1 1 1 0 Ribosomal L37ae protein family Autophagy_N PF03986.8 CBZ54613.1 - 1.9e-31 108.8 0.0 2.9e-31 108.1 0.0 1.3 1 0 0 1 1 1 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_act_C PF03987.10 CBZ54613.1 - 4.2e-27 94.1 0.1 7.2e-27 93.3 0.1 1.4 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Autophagy_Cterm PF10381.4 CBZ54613.1 - 3.1e-12 45.3 1.1 5.5e-12 44.5 0.7 1.4 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal SRP9-21 PF05486.7 CBZ54615.1 - 8.4e-15 54.2 0.2 1.9e-14 53.1 0.0 1.6 2 0 0 2 2 2 1 Signal recognition particle 9 kDa protein (SRP9) ATP-synt_ab PF00006.20 CBZ54616.1 - 1.4e-06 27.9 0.4 0.034 13.6 0.0 2.3 2 0 0 2 2 2 2 ATP synthase alpha/beta family, nucleotide-binding domain NACHT PF05729.7 CBZ54616.1 - 0.017 14.7 0.0 0.43 10.2 0.0 2.9 3 0 0 3 3 3 0 NACHT domain AAA_25 PF13481.1 CBZ54616.1 - 0.022 14.1 0.6 0.077 12.3 0.1 2.0 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.1 CBZ54616.1 - 0.05 13.7 0.0 0.58 10.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 CBZ54616.1 - 0.2 11.0 0.4 1 8.6 0.4 2.0 2 0 0 2 2 2 0 AAA-like domain DNA_mis_repair PF01119.14 CBZ54618.1 - 7.4e-16 57.6 0.0 1.3e-15 56.8 0.0 1.4 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain MutL_C PF08676.6 CBZ54618.1 - 1.2e-11 44.4 0.2 1.7e-08 34.1 0.0 2.7 2 0 0 2 2 2 2 MutL C terminal dimerisation domain HATPase_c_3 PF13589.1 CBZ54618.1 - 3.9e-10 39.5 0.0 1.7e-09 37.4 0.0 2.1 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 CBZ54618.1 - 4.5e-10 39.2 0.0 9e-10 38.2 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Peptidase_M16 PF00675.15 CBZ54619.1 - 1.3e-53 180.7 0.2 6e-53 178.5 0.1 2.0 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 CBZ54619.1 - 9e-29 100.4 0.0 6.2e-28 97.7 0.0 2.4 2 2 0 2 2 2 1 Peptidase M16 inactive domain PCI PF01399.22 CBZ54620.1 - 1.3e-09 38.3 0.0 4.9e-09 36.4 0.0 2.1 1 0 0 1 1 1 1 PCI domain PCI_Csn8 PF10075.4 CBZ54620.1 - 0.0013 18.5 0.0 0.0028 17.4 0.0 1.5 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 TPR_12 PF13424.1 CBZ54620.1 - 0.006 16.4 5.3 0.25 11.2 0.4 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 CBZ54620.1 - 0.049 13.4 5.6 0.68 9.8 0.1 4.2 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.1 CBZ54620.1 - 0.1 12.9 1.6 0.98 9.8 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat CTV_P33 PF07184.6 CBZ54620.1 - 0.16 10.7 0.0 0.25 10.1 0.0 1.2 1 0 0 1 1 1 0 Citrus tristeza virus P33 protein TPR_16 PF13432.1 CBZ54620.1 - 0.24 12.1 7.7 0.37 11.5 0.7 3.4 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 CBZ54620.1 - 0.29 11.6 7.3 92 3.8 0.0 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.1 CBZ54620.1 - 3.5 8.5 11.5 26 5.8 0.0 5.4 6 1 0 6 6 6 0 Tetratricopeptide repeat Pkinase PF00069.20 CBZ54621.1 - 1.9e-36 125.5 0.0 2.9e-36 124.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ54621.1 - 1.4e-19 70.2 0.0 4.4e-19 68.5 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBZ54621.1 - 0.083 11.8 0.0 0.12 11.2 0.0 1.2 1 0 0 1 1 1 0 Kinase-like RCC1 PF00415.13 CBZ54622.1 - 4.9e-16 58.6 15.2 3.2e-10 40.0 0.0 7.0 7 1 0 7 7 7 3 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 CBZ54622.1 - 3.1e-15 55.3 24.3 3.9e-09 35.8 0.6 4.9 5 0 0 5 5 5 3 Regulator of chromosome condensation (RCC1) repeat HIRA_B PF09453.5 CBZ54622.1 - 0.00094 18.6 0.3 0.0024 17.3 0.2 1.7 1 0 0 1 1 1 1 HIRA B motif PP2C PF00481.16 CBZ54623.1 - 1.4e-41 142.6 0.1 8.1e-40 136.8 0.0 3.0 2 1 0 2 2 2 1 Protein phosphatase 2C zf-RING_5 PF14634.1 CBZ54624.1 - 3.5e-05 23.4 9.8 5.8e-05 22.7 6.8 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 CBZ54624.1 - 0.0037 17.2 11.9 0.0062 16.5 8.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CBZ54624.1 - 0.0068 16.0 10.6 0.011 15.3 7.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CBZ54624.1 - 0.039 13.7 10.6 0.075 12.8 7.3 1.5 1 0 0 1 1 1 0 Ring finger domain DUF2732 PF10809.3 CBZ54624.1 - 0.12 11.9 0.1 0.24 10.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2732) zf-C4H2 PF10146.4 CBZ54624.1 - 5 7.0 8.8 2 8.3 0.6 2.4 2 0 0 2 2 2 0 Zinc finger-containing protein zf-C2H2_4 PF13894.1 CBZ54624.1 - 7.5 7.1 10.2 2.2 8.7 0.1 3.6 3 1 0 3 3 3 0 C2H2-type zinc finger TBP PF00352.16 CBZ54625.1 - 2.4e-10 39.6 0.0 0.00032 20.0 0.0 2.9 3 0 0 3 3 3 2 Transcription factor TFIID (or TATA-binding protein, TBP) Ctr PF04145.10 CBZ54626.1 - 0.012 15.7 0.1 0.035 14.1 0.0 2.0 2 1 0 2 2 2 0 Ctr copper transporter family DUF2453 PF10507.4 CBZ54628.1 - 4e-27 94.2 0.0 6.5e-27 93.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2453) GAF_3 PF13492.1 CBZ54628.1 - 1.5e-09 38.0 0.0 0.00017 21.7 0.0 2.7 3 0 0 3 3 3 2 GAF domain GAF PF01590.21 CBZ54628.1 - 1.7e-07 31.4 0.0 9.5e-05 22.5 0.0 2.6 2 0 0 2 2 2 2 GAF domain GAF_2 PF13185.1 CBZ54628.1 - 1.8e-07 31.7 0.0 5.3e-07 30.2 0.0 1.8 2 0 0 2 2 2 1 GAF domain Apt1 PF10351.4 CBZ54628.1 - 9.2 5.0 19.4 15 4.2 12.8 1.8 2 0 0 2 2 2 0 Golgi-body localisation protein domain Cullin_binding PF03556.10 CBZ54630.1 - 6e-31 107.0 0.3 9.7e-31 106.3 0.2 1.3 1 0 0 1 1 1 1 Cullin binding UBA_4 PF14555.1 CBZ54630.1 - 9.7e-11 41.0 0.1 1.7e-10 40.2 0.1 1.4 1 0 0 1 1 1 1 UBA-like domain RRM_6 PF14259.1 CBZ54631.1 - 1.6e-35 120.8 0.0 7.7e-11 41.8 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CBZ54631.1 - 2.1e-24 84.9 0.0 1.5e-07 30.9 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBZ54631.1 - 1.7e-13 50.2 0.0 0.00077 19.2 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Lysine_decarbox PF03641.9 CBZ54634.1 - 2e-23 82.6 0.0 3.6e-23 81.8 0.0 1.4 1 0 0 1 1 1 1 Possible lysine decarboxylase Retrotrans_gag PF03732.12 CBZ54634.1 - 0.11 12.5 0.5 0.22 11.5 0.3 1.4 1 0 0 1 1 1 0 Retrotransposon gag protein Ribosomal_L7Ae PF01248.21 CBZ54635.1 - 1.3e-26 91.9 0.2 1.5e-26 91.6 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.6 CBZ54635.1 - 0.01 15.7 0.0 0.01 15.6 0.0 1.2 1 0 0 1 1 1 0 RNase P subunit Pop3 PELOTA_1 PF15608.1 CBZ54635.1 - 0.1 12.3 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 PELOTA RNA binding domain Ank_2 PF12796.2 CBZ54636.1 - 1.5e-08 34.8 0.0 2e-08 34.4 0.0 1.1 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 CBZ54636.1 - 1.7e-08 34.4 0.6 0.00013 22.0 0.1 2.2 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 CBZ54636.1 - 4e-06 26.3 0.0 0.0043 16.7 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.1 CBZ54636.1 - 4.5e-06 27.0 0.0 6.8e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 CBZ54636.1 - 1.3e-05 24.9 0.1 0.22 11.8 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeat Pkinase PF00069.20 CBZ54637.1 - 6.6e-08 32.0 0.0 4.4e-07 29.3 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ54637.1 - 3.6e-05 22.9 0.0 8.5e-05 21.7 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBZ54637.1 - 0.00014 20.9 0.0 0.00021 20.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like HMG_box_5 PF14887.1 CBZ54637.1 - 0.5 10.1 4.2 0.24 11.1 0.5 2.2 2 0 0 2 2 2 0 HMG (high mobility group) box 5 zf-RING_2 PF13639.1 CBZ54639.1 - 2.6e-14 52.7 7.8 4.9e-14 51.8 5.4 1.5 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 CBZ54639.1 - 6.1e-10 39.0 4.2 1.6e-09 37.7 2.9 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 CBZ54639.1 - 6.5e-07 29.2 8.6 1.2e-06 28.4 6.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CBZ54639.1 - 1.9e-06 27.3 8.0 3.6e-06 26.5 5.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CBZ54639.1 - 3e-06 26.7 4.9 5.6e-06 25.9 3.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBZ54639.1 - 4.9e-05 22.9 7.4 9.8e-05 22.0 5.1 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 CBZ54639.1 - 0.0015 18.3 1.5 0.0034 17.1 1.1 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger RINGv PF12906.2 CBZ54639.1 - 0.023 14.7 9.6 0.023 14.7 6.6 2.1 2 0 0 2 2 2 0 RING-variant domain Baculo_RING PF05883.6 CBZ54639.1 - 0.1 12.4 0.8 0.23 11.3 0.5 1.6 1 0 0 1 1 1 0 Baculovirus U-box/Ring-like domain zf-Nse PF11789.3 CBZ54639.1 - 0.1 12.1 3.1 0.21 11.1 2.1 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit FANCL_C PF11793.3 CBZ54639.1 - 0.21 11.6 7.0 0.6 10.1 4.9 1.8 1 1 0 1 1 1 0 FANCL C-terminal domain DEAD PF00270.24 CBZ54640.1 - 3e-42 143.9 0.0 5.8e-42 143.0 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CBZ54640.1 - 4.8e-28 96.8 0.0 9.9e-28 95.8 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 CBZ54640.1 - 0.0007 19.4 0.0 0.0028 17.5 0.0 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.1 CBZ54640.1 - 0.00078 19.1 0.0 0.42 10.4 0.0 3.0 2 1 0 2 2 2 2 Part of AAA domain Helicase_C_2 PF13307.1 CBZ54640.1 - 0.16 11.9 0.0 0.33 10.8 0.0 1.5 1 0 0 1 1 1 0 Helicase C-terminal domain START PF01852.14 CBZ54641.1 - 7.1e-14 51.6 0.1 1.4e-13 50.6 0.1 1.4 1 0 0 1 1 1 1 START domain DUF1789 PF08748.6 CBZ54644.1 - 0.025 14.7 4.8 0.092 12.8 0.5 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF1789) ApoLp-III PF07464.6 CBZ54644.1 - 0.3 11.0 6.0 11 5.9 0.1 3.1 2 1 1 3 3 3 0 Apolipophorin-III precursor (apoLp-III) V-SNARE PF05008.10 CBZ54644.1 - 0.31 11.2 8.2 3 8.0 0.1 3.3 2 1 1 3 3 3 0 Vesicle transport v-SNARE protein N-terminus TBPIP PF07106.8 CBZ54644.1 - 0.38 10.2 3.5 0.44 10.0 0.3 2.1 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) SF-assemblin PF06705.6 CBZ54644.1 - 0.49 9.5 8.8 0.049 12.7 1.8 2.0 1 1 0 2 2 2 0 SF-assemblin/beta giardin YlqD PF11068.3 CBZ54644.1 - 8.5 6.4 9.4 2.7 8.0 2.1 2.4 2 1 0 2 2 2 0 YlqD protein YbjM PF11045.3 CBZ54645.1 - 0.099 12.4 0.0 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 Putative inner membrane protein of Enterobacteriaceae zf-C2HC_2 PF13913.1 CBZ54648.1 - 9.4e-14 50.6 11.5 1.4e-08 34.2 0.8 2.6 2 0 0 2 2 2 2 zinc-finger of a C2HC-type zf-Di19 PF05605.7 CBZ54648.1 - 2.3 8.4 4.5 6.5 6.9 1.3 2.5 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Hydrolase PF00702.21 CBZ54649.1 - 1.4e-21 77.8 0.0 2.5e-08 34.6 0.0 3.8 2 1 0 3 3 3 3 haloacid dehalogenase-like hydrolase HAD PF12710.2 CBZ54649.1 - 8.5e-20 71.7 0.0 6.4e-19 68.8 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 CBZ54649.1 - 3e-15 55.9 0.0 3.7e-14 52.3 0.0 2.3 1 1 0 1 1 1 1 E1-E2 ATPase Hydrolase_like2 PF13246.1 CBZ54649.1 - 0.0045 16.9 0.0 0.012 15.5 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit DUF4128 PF13554.1 CBZ54649.1 - 0.15 11.6 0.1 0.33 10.6 0.0 1.4 1 0 0 1 1 1 0 Bacteriophage related domain of unknown function Vps39_1 PF10366.4 CBZ54649.1 - 1.4 8.9 2.7 3.9 7.5 1.9 1.7 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 1 DSS1_SEM1 PF05160.8 CBZ54654.1 - 1.6e-07 30.9 22.0 7.9e-06 25.5 15.2 2.3 1 1 0 1 1 1 1 DSS1/SEM1 family MatP PF06303.7 CBZ54654.1 - 0.029 14.3 0.0 0.035 14.0 0.0 1.2 1 0 0 1 1 1 0 Organiser of macrodomain of Terminus of chromosome DUF4404 PF14357.1 CBZ54654.1 - 0.12 12.7 0.8 0.3 11.5 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) MFS_1 PF07690.11 CBZ54658.1 - 3.2e-11 42.5 31.3 1.5e-09 37.0 9.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Gly-zipper_Omp PF13488.1 CBZ54658.1 - 0.018 14.6 1.7 4.8 6.9 0.0 2.7 2 0 0 2 2 2 0 Glycine zipper Hairpins PF04877.7 CBZ54658.1 - 0.032 13.6 0.1 1 8.7 0.2 2.1 1 1 1 2 2 2 0 HrpZ Transgly_assoc PF04226.8 CBZ54658.1 - 0.033 14.2 5.6 0.76 9.9 0.6 3.0 2 0 0 2 2 2 0 Transglycosylase associated protein Rick_17kDa_Anti PF05433.10 CBZ54658.1 - 0.74 9.5 3.4 16 5.2 0.5 2.5 2 0 0 2 2 2 0 Glycine zipper 2TM domain Bacteriocin_IIc PF10439.4 CBZ54658.1 - 1.9 8.6 6.9 8.2 6.6 0.4 2.9 3 0 0 3 3 3 0 Bacteriocin class II with double-glycine leader peptide Sugar_tr PF00083.19 CBZ54658.1 - 2.1 6.8 21.0 0.42 9.1 1.8 3.3 1 1 1 3 3 3 0 Sugar (and other) transporter SNF2_N PF00176.18 CBZ54659.1 - 1.8e-56 191.1 0.0 1.8e-56 191.1 0.0 1.9 2 0 0 2 2 2 1 SNF2 family N-terminal domain PHD PF00628.24 CBZ54659.1 - 7.5e-21 73.5 76.3 5.6e-09 35.5 4.9 6.7 6 1 0 6 6 6 4 PHD-finger Helicase_C PF00271.26 CBZ54659.1 - 7.9e-14 51.2 0.0 3.3e-13 49.2 0.0 2.2 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 CBZ54659.1 - 0.0001 21.8 0.0 0.00025 20.5 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase C1_1 PF00130.17 CBZ54659.1 - 0.0039 16.8 2.0 0.0039 16.8 1.4 6.8 5 1 1 6 6 6 3 Phorbol esters/diacylglycerol binding domain (C1 domain) AAA_14 PF13173.1 CBZ54659.1 - 0.0073 16.2 0.0 0.018 14.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain zf-PHD-like PF15446.1 CBZ54659.1 - 0.026 13.8 0.0 0.026 13.8 0.0 7.2 4 2 2 6 6 6 0 PHD/FYVE-zinc-finger like domain Rubredoxin PF00301.15 CBZ54659.1 - 0.59 10.0 26.9 0.89 9.4 2.6 4.1 3 0 0 3 3 3 0 Rubredoxin Ycf1 PF05758.7 CBZ54659.1 - 6.2 4.4 11.0 13 3.3 7.6 1.4 1 0 0 1 1 1 0 Ycf1 TFIIS_M PF07500.9 CBZ54660.1 - 7.3 6.6 18.2 2.1 8.4 0.3 5.2 5 2 1 6 6 6 0 Transcription factor S-II (TFIIS), central domain AMP-binding PF00501.23 CBZ54661.1 - 2.9e-33 114.8 0.0 1.3e-32 112.7 0.0 1.8 1 1 0 1 1 1 1 AMP-binding enzyme KR PF08659.5 CBZ54662.1 - 3.2e-27 95.3 0.2 7.7e-27 94.1 0.1 1.7 2 0 0 2 2 2 1 KR domain ketoacyl-synt PF00109.21 CBZ54662.1 - 4.9e-22 78.6 0.6 1.2e-21 77.4 0.0 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain adh_short PF00106.20 CBZ54662.1 - 3.3e-15 56.4 0.1 9.9e-15 54.8 0.0 1.8 2 0 0 2 2 2 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 CBZ54662.1 - 6.8e-10 38.8 0.0 1.5e-09 37.7 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.20 CBZ54662.1 - 4.3e-08 33.3 0.1 1.3e-07 31.7 0.1 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site Acyl_transf_1 PF00698.16 CBZ54662.1 - 2.6e-07 30.2 0.7 5.7e-07 29.1 0.2 1.7 2 0 0 2 2 2 1 Acyl transferase domain CRAL_TRIO PF00650.15 CBZ54663.1 - 3.4e-17 62.3 0.1 1e-09 38.0 0.0 2.2 1 1 1 2 2 2 2 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 CBZ54663.1 - 0.0018 18.3 0.0 0.0037 17.3 0.0 1.5 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain HdeA PF06411.6 CBZ54663.1 - 0.035 14.0 0.0 0.14 12.1 0.0 1.9 2 0 0 2 2 2 0 HdeA/HdeB family FAST_1 PF06743.10 CBZ54664.1 - 5.2e-07 29.2 0.9 2.2 8.0 0.1 5.5 1 1 3 5 5 5 4 FAST kinase-like protein, subdomain 1 RAP PF08373.5 CBZ54664.1 - 2e-05 24.2 0.1 3.8e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 RAP domain RNase_T PF00929.19 CBZ54665.1 - 5.2e-16 59.3 0.0 8.6e-16 58.6 0.0 1.4 1 0 0 1 1 1 1 Exonuclease DUF1298 PF06974.8 CBZ54666.1 - 9.3e-06 25.5 0.0 1.8e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1298) Nucleo_P87 PF07267.6 CBZ54669.1 - 3.1 6.3 14.5 0.54 8.8 0.9 2.1 2 0 0 2 2 2 0 Nucleopolyhedrovirus capsid protein P87 AP2 PF00847.15 CBZ54670.1 - 0.004 17.2 0.9 0.004 17.2 0.6 3.2 3 0 0 3 3 3 1 AP2 domain RAP PF08373.5 CBZ54671.1 - 9.3e-15 54.1 0.0 1.7e-14 53.3 0.0 1.5 1 0 0 1 1 1 1 RAP domain FAST_1 PF06743.10 CBZ54671.1 - 3.2 7.5 9.3 8.8 6.1 0.1 4.7 4 1 0 5 5 5 0 FAST kinase-like protein, subdomain 1 DNA_pol3_delta2 PF13177.1 CBZ54672.1 - 5.7e-17 61.8 0.0 9.3e-17 61.1 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.24 CBZ54672.1 - 8.4e-15 55.1 0.0 1.5e-14 54.3 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 CBZ54672.1 - 5.5e-08 33.0 0.0 1.2e-07 31.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 CBZ54672.1 - 2.3e-06 27.7 0.1 2.7e-05 24.2 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain Rep_fac_C PF08542.6 CBZ54672.1 - 2.4e-06 27.4 0.0 6.8e-06 25.9 0.0 1.8 1 0 0 1 1 1 1 Replication factor C C-terminal domain Rad17 PF03215.10 CBZ54672.1 - 3.1e-06 26.1 0.0 0.0025 16.5 0.0 2.1 2 0 0 2 2 2 2 Rad17 cell cycle checkpoint protein RuvB_N PF05496.7 CBZ54672.1 - 6.7e-05 22.0 0.0 0.00017 20.7 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_30 PF13604.1 CBZ54672.1 - 0.00013 21.5 0.3 0.0015 18.1 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.1 CBZ54672.1 - 0.00016 21.3 0.0 0.00053 19.6 0.0 1.9 1 0 0 1 1 1 1 Part of AAA domain AAA_25 PF13481.1 CBZ54672.1 - 0.00033 20.1 0.1 0.0015 17.9 0.0 2.2 1 1 1 2 2 2 1 AAA domain DUF2075 PF09848.4 CBZ54672.1 - 0.00041 19.4 0.0 0.00066 18.7 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) DEAD PF00270.24 CBZ54672.1 - 0.00068 19.1 0.0 0.11 12.0 0.0 2.4 1 1 0 2 2 2 1 DEAD/DEAH box helicase AAA_11 PF13086.1 CBZ54672.1 - 0.00089 18.9 0.0 0.0023 17.5 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_10 PF12846.2 CBZ54672.1 - 0.0011 18.4 0.1 1.2 8.5 0.0 3.1 3 0 0 3 3 3 1 AAA-like domain AAA_5 PF07728.9 CBZ54672.1 - 0.0015 18.2 0.0 0.45 10.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) TIP49 PF06068.8 CBZ54672.1 - 0.0017 17.1 0.0 0.13 10.9 0.0 2.3 2 0 0 2 2 2 1 TIP49 C-terminus Mg_chelatase PF01078.16 CBZ54672.1 - 0.0051 16.0 0.0 0.052 12.7 0.0 2.1 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.12 CBZ54672.1 - 0.0054 16.1 0.0 0.12 11.7 0.0 2.2 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_14 PF13173.1 CBZ54672.1 - 0.0058 16.5 0.0 0.055 13.3 0.0 2.1 1 1 0 1 1 1 1 AAA domain SNF2_N PF00176.18 CBZ54672.1 - 0.0059 15.4 0.0 0.083 11.6 0.0 2.1 2 0 0 2 2 2 1 SNF2 family N-terminal domain FtsK_SpoIIIE PF01580.13 CBZ54672.1 - 0.01 15.2 0.0 0.14 11.6 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_24 PF13479.1 CBZ54672.1 - 0.017 14.6 0.0 0.037 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 CBZ54672.1 - 0.022 14.9 0.0 0.12 12.5 0.0 2.2 2 0 0 2 2 2 0 RNA helicase KTI12 PF08433.5 CBZ54672.1 - 0.024 13.8 0.2 0.078 12.1 0.0 2.0 2 1 0 2 2 2 0 Chromatin associated protein KTI12 AAA_17 PF13207.1 CBZ54672.1 - 0.027 15.2 0.1 0.073 13.8 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.1 CBZ54672.1 - 0.028 14.7 0.0 0.077 13.3 0.0 1.8 1 1 0 1 1 1 0 AAA domain PhoH PF02562.11 CBZ54672.1 - 0.029 13.5 0.0 2.3 7.3 0.0 2.2 2 0 0 2 2 2 0 PhoH-like protein AAA_28 PF13521.1 CBZ54672.1 - 0.065 13.1 0.3 3.5 7.5 0.0 2.7 3 0 0 3 3 2 0 AAA domain Arch_ATPase PF01637.13 CBZ54672.1 - 0.081 12.6 0.0 0.24 11.0 0.0 1.8 1 1 0 1 1 1 0 Archaeal ATPase AAA_33 PF13671.1 CBZ54672.1 - 0.099 12.5 0.1 0.29 11.0 0.0 1.8 1 1 0 1 1 1 0 AAA domain PIF1 PF05970.9 CBZ54672.1 - 0.1 11.5 0.0 2 7.2 0.1 2.1 2 0 0 2 2 2 0 PIF1-like helicase Zot PF05707.7 CBZ54672.1 - 0.18 11.2 0.7 4 6.8 0.5 2.7 1 1 0 1 1 1 0 Zonular occludens toxin (Zot) SOR_SNZ PF01680.12 CBZ54673.1 - 3.1e-108 360.1 5.6 3.1e-108 360.1 3.9 1.5 2 0 0 2 2 2 1 SOR/SNZ family ThiG PF05690.9 CBZ54673.1 - 2.1e-07 30.2 8.3 9.9e-07 28.0 0.3 2.7 2 1 1 3 3 3 2 Thiazole biosynthesis protein ThiG NanE PF04131.9 CBZ54673.1 - 0.00015 20.8 0.6 0.027 13.4 0.0 2.5 2 1 0 2 2 2 2 Putative N-acetylmannosamine-6-phosphate epimerase PEP_mutase PF13714.1 CBZ54673.1 - 0.003 16.7 0.7 0.092 11.9 0.2 2.4 2 1 0 2 2 2 1 Phosphoenolpyruvate phosphomutase NMO PF03060.10 CBZ54673.1 - 0.012 14.8 5.3 0.11 11.5 0.1 2.3 2 0 0 2 2 2 0 Nitronate monooxygenase His_biosynth PF00977.16 CBZ54673.1 - 0.013 14.7 0.2 0.14 11.3 0.0 2.3 2 1 0 2 2 2 0 Histidine biosynthesis protein Dus PF01207.12 CBZ54673.1 - 0.015 14.1 1.9 1.6 7.5 0.0 2.6 3 0 0 3 3 3 0 Dihydrouridine synthase (Dus) OMPdecase PF00215.19 CBZ54673.1 - 0.046 13.1 0.1 3.7 6.8 0.0 2.6 2 1 1 3 3 3 0 Orotidine 5'-phosphate decarboxylase / HUMPS family IGPS PF00218.16 CBZ54673.1 - 0.06 12.3 0.0 0.3 10.0 0.0 2.0 2 0 0 2 2 2 0 Indole-3-glycerol phosphate synthase MttA_Hcf106 PF02416.11 CBZ54673.1 - 0.2 10.8 1.0 1.2 8.3 0.1 2.4 2 0 0 2 2 2 0 mttA/Hcf106 family Peptidase_A22B PF04258.8 CBZ54674.1 - 2.1e-61 207.9 6.9 9.1e-49 166.5 4.2 2.2 2 0 0 2 2 2 2 Signal peptide peptidase PRA1 PF03208.14 CBZ54674.1 - 0.073 12.4 4.9 0.76 9.1 0.0 3.7 4 0 0 4 4 4 0 PRA1 family protein FliT PF05400.8 CBZ54677.1 - 0.0073 16.6 5.3 0.0073 16.6 3.7 2.9 1 1 1 2 2 2 1 Flagellar protein FliT AF0941-like PF14591.1 CBZ54677.1 - 0.038 14.0 5.1 0.025 14.6 2.0 1.8 1 1 0 1 1 1 0 AF0941-like Katanin_con80 PF13925.1 CBZ54677.1 - 0.052 13.2 0.3 0.052 13.2 0.2 2.2 2 1 0 2 2 2 0 con80 domain of Katanin DUF2870 PF11069.3 CBZ54677.1 - 0.97 9.5 6.2 1.5 8.9 2.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2870) DUF3529 PF12046.3 CBZ54677.1 - 1.4 7.8 6.0 0.49 9.4 2.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3529) FlgN PF05130.7 CBZ54677.1 - 6.8 6.9 15.4 0.57 10.4 1.4 2.4 1 1 0 2 2 2 0 FlgN protein FA_desaturase PF00487.19 CBZ54680.1 - 2.7e-28 99.0 12.8 4.1e-28 98.5 8.9 1.2 1 0 0 1 1 1 1 Fatty acid desaturase Lipid_DES PF08557.5 CBZ54680.1 - 1.4e-16 59.4 1.1 2.3e-16 58.7 0.8 1.4 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) CHD5 PF04420.9 CBZ54680.1 - 2.6 7.6 4.4 3.6 7.2 0.3 2.3 2 0 0 2 2 2 0 CHD5-like protein Pkinase PF00069.20 CBZ54681.1 - 3.2e-43 147.7 0.0 3.8e-30 104.9 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ54681.1 - 9e-43 146.1 0.0 1.5e-42 145.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CBZ54681.1 - 0.026 14.2 0.0 0.076 12.7 0.0 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family MCM PF00493.18 CBZ54682.1 - 2.6e-118 394.6 0.0 3.6e-118 394.1 0.0 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 CBZ54682.1 - 8.4e-09 35.9 0.1 2.8e-08 34.2 0.1 1.9 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 CBZ54682.1 - 5e-08 32.3 0.1 6.8e-05 22.1 0.1 2.4 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 CBZ54682.1 - 3.3e-06 26.8 0.0 8.4e-06 25.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 CBZ54682.1 - 3e-05 23.6 0.0 7e-05 22.4 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 CBZ54682.1 - 0.094 12.0 1.1 5.1 6.4 0.0 2.8 2 1 0 2 2 2 0 AAA domain AAA PF00004.24 CBZ54682.1 - 0.099 12.8 0.0 0.37 10.9 0.0 2.0 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Zn-ribbon_8 PF09723.5 CBZ54682.1 - 0.13 12.2 1.9 0.3 11.0 1.3 1.6 1 0 0 1 1 1 0 Zinc ribbon domain WGG PF10273.4 CBZ54684.1 - 8.1e-16 57.8 0.1 1.3e-15 57.2 0.1 1.3 1 0 0 1 1 1 1 Pre-rRNA-processing protein TSR2 EMP24_GP25L PF01105.19 CBZ54685.1 - 5e-17 62.2 0.0 6e-17 61.9 0.0 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF1014 PF06244.7 CBZ54686.1 - 2e-36 124.8 6.4 2e-36 124.8 4.5 2.3 2 1 0 2 2 2 1 Protein of unknown function (DUF1014) HMG_box PF00505.14 CBZ54686.1 - 0.00047 20.3 0.7 0.00047 20.3 0.5 3.2 3 2 0 3 3 3 1 HMG (high mobility group) box CHDNT PF08073.7 CBZ54686.1 - 0.087 12.5 0.2 0.15 11.7 0.1 1.3 1 0 0 1 1 1 0 CHDNT (NUC034) domain YABBY PF04690.8 CBZ54686.1 - 0.55 10.4 13.8 0.043 14.0 1.9 2.1 1 1 1 2 2 2 0 YABBY protein Pneumo_att_G PF05539.6 CBZ54686.1 - 1.1 8.5 4.6 1.4 8.2 3.2 1.1 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G TLD PF07534.11 CBZ54687.1 - 1.7e-23 83.1 0.0 2.8e-23 82.4 0.0 1.3 1 0 0 1 1 1 1 TLD RabGAP-TBC PF00566.13 CBZ54687.1 - 4.5e-14 52.4 0.0 6.6e-14 51.8 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain LRR_6 PF13516.1 CBZ54688.1 - 0.001 18.8 0.1 2.3 8.5 0.0 3.8 2 1 1 3 3 3 2 Leucine Rich repeat PP2C PF00481.16 CBZ54689.1 - 2.4e-25 89.3 0.0 5.3e-19 68.6 0.0 3.4 2 1 0 2 2 2 2 Protein phosphatase 2C AP2 PF00847.15 CBZ54690.1 - 3.6 7.8 5.6 5.5 7.2 0.3 2.4 2 0 0 2 2 2 0 AP2 domain CAP PF00188.21 CBZ54691.1 - 2.1e-08 34.6 0.1 5e-08 33.4 0.1 1.6 1 0 0 1 1 1 1 Cysteine-rich secretory protein family CAP PF00188.21 CBZ54692.1 - 0.00032 21.1 0.0 0.0013 19.2 0.0 1.9 1 1 0 1 1 1 1 Cysteine-rich secretory protein family DER1 PF04511.10 CBZ54693.1 - 1.5e-13 50.7 0.0 5.7e-06 25.9 0.0 3.1 3 0 0 3 3 3 3 Der1-like family GCV_T PF01571.16 CBZ54694.1 - 1.3e-50 171.7 0.2 1.6e-49 168.1 0.1 2.1 1 1 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 CBZ54694.1 - 5.2e-12 45.6 0.2 2.8e-11 43.2 0.0 2.2 2 0 0 2 2 2 1 Glycine cleavage T-protein C-terminal barrel domain IMS PF00817.15 CBZ54695.1 - 1.6e-18 66.9 0.0 3e-18 66.0 0.0 1.4 1 0 0 1 1 1 1 impB/mucB/samB family BRCT PF00533.21 CBZ54695.1 - 3e-06 27.2 0.0 6.2e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain IMS_C PF11799.3 CBZ54695.1 - 0.00055 19.8 0.0 0.0017 18.3 0.0 1.8 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.3 CBZ54695.1 - 0.00059 19.7 0.0 0.0016 18.3 0.0 1.8 1 0 0 1 1 1 1 IMS family HHH motif EF-hand_6 PF13405.1 CBZ54696.1 - 1.1e-14 52.9 1.1 1.3e-08 33.9 0.2 4.3 4 1 1 5 5 5 3 EF-hand domain EF-hand_7 PF13499.1 CBZ54696.1 - 1.9e-13 50.3 0.1 4.3e-08 33.1 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 CBZ54696.1 - 5.7e-11 41.8 2.0 0.0049 16.4 0.0 4.1 3 1 1 4 4 4 4 EF-hand domain pair EF-hand_1 PF00036.27 CBZ54696.1 - 3.2e-10 38.5 4.3 9.8e-08 30.7 0.1 4.2 5 0 0 5 5 5 1 EF hand EF-hand_5 PF13202.1 CBZ54696.1 - 1.6e-05 24.0 0.3 1.6e-05 24.0 0.2 3.0 3 0 0 3 3 3 1 EF hand EF-hand_9 PF14658.1 CBZ54696.1 - 0.00046 20.0 0.0 0.0034 17.2 0.0 2.0 2 0 0 2 2 2 1 EF-hand domain Pterin_bind PF00809.17 CBZ54696.1 - 0.006 15.9 0.0 0.013 14.9 0.0 1.4 1 1 0 1 1 1 1 Pterin binding enzyme DUF3847 PF12958.2 CBZ54696.1 - 0.043 13.5 0.1 2.1 8.1 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3847) PP2C PF00481.16 CBZ54697.1 - 2.5e-42 145.0 0.0 5.2e-42 143.9 0.0 1.6 2 0 0 2 2 2 1 Protein phosphatase 2C SpoIIE PF07228.7 CBZ54697.1 - 0.0088 15.7 0.0 0.029 14.0 0.0 1.9 2 0 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) KH_1 PF00013.24 CBZ54701.1 - 9.2e-08 31.6 0.2 2.3e-07 30.3 0.2 1.6 1 0 0 1 1 1 1 KH domain KH_3 PF13014.1 CBZ54701.1 - 4.5e-05 23.0 0.1 0.00011 21.7 0.1 1.7 1 0 0 1 1 1 1 KH domain KH_2 PF07650.12 CBZ54701.1 - 0.0058 16.1 0.1 0.011 15.2 0.1 1.3 1 0 0 1 1 1 1 KH domain rve_3 PF13683.1 CBZ54701.1 - 0.095 12.2 0.0 0.23 11.0 0.0 1.7 1 0 0 1 1 1 0 Integrase core domain NifU_N PF01592.11 CBZ54703.1 - 1e-46 157.9 0.0 1.5e-46 157.4 0.0 1.2 1 0 0 1 1 1 1 NifU-like N terminal domain LCM PF04072.9 CBZ54704.1 - 5e-23 81.5 0.4 1.1e-20 73.9 0.0 2.2 2 0 0 2 2 2 2 Leucine carboxyl methyltransferase PADR1 PF08063.7 CBZ54705.1 - 0.081 12.3 5.2 0.062 12.7 0.2 2.9 3 0 0 3 3 3 0 PADR1 (NUC008) domain Arm PF00514.18 CBZ54706.1 - 1.9e-12 46.4 40.6 1.3e-05 24.8 0.5 8.9 10 0 0 10 10 10 5 Armadillo/beta-catenin-like repeat DNA_photolyase PF00875.13 CBZ54706.1 - 0.021 14.5 0.3 0.045 13.4 0.2 1.5 1 0 0 1 1 1 0 DNA photolyase FbpA PF05833.6 CBZ54708.1 - 7.6e-28 97.2 20.1 2.1e-22 79.2 0.0 3.0 3 0 0 3 3 3 2 Fibronectin-binding protein A N-terminus (FbpA) DUF814 PF05670.8 CBZ54708.1 - 1.4e-22 79.3 0.0 5.1e-22 77.5 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF814) DUF3441 PF11923.3 CBZ54708.1 - 1.1e-21 76.5 1.7 1.6e-21 76.0 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3441) Aminotran_1_2 PF00155.16 CBZ54708.1 - 0.09 11.7 1.1 0.22 10.4 0.8 1.6 1 0 0 1 1 1 0 Aminotransferase class I and II Yip1 PF04893.12 CBZ54709.1 - 8.5e-11 41.6 11.6 1.3e-10 41.1 8.0 1.3 1 0 0 1 1 1 1 Yip1 domain Atg14 PF10186.4 CBZ54710.1 - 0.00036 19.5 0.0 0.0048 15.8 0.0 2.2 2 0 0 2 2 2 1 UV radiation resistance protein and autophagy-related subunit 14 ING PF12998.2 CBZ54712.1 - 0.075 13.3 0.9 0.16 12.2 0.6 1.5 1 0 0 1 1 1 0 Inhibitor of growth proteins N-terminal histone-binding Tim17 PF02466.14 CBZ54713.1 - 1.9e-14 53.8 4.6 2.3e-14 53.5 3.2 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family LRR_4 PF12799.2 CBZ54714.1 - 0.012 15.2 0.6 0.031 13.8 0.4 1.8 1 1 0 1 1 1 0 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 CBZ54714.1 - 0.099 12.7 0.9 13 6.3 0.1 3.1 2 0 0 2 2 2 0 Leucine Rich Repeat ENTH PF01417.15 CBZ54715.1 - 7.2e-35 119.5 0.0 9.9e-35 119.1 0.0 1.2 1 0 0 1 1 1 1 ENTH domain VHS PF00790.14 CBZ54715.1 - 0.14 11.8 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 VHS domain ANTH PF07651.11 CBZ54715.1 - 0.25 10.0 0.0 0.36 9.4 0.0 1.2 1 0 0 1 1 1 0 ANTH domain SAG PF04092.8 CBZ54716.1 - 2.1e-08 34.5 4.8 0.00014 22.2 1.5 2.3 2 0 0 2 2 2 2 SRS domain WD40 PF00400.27 CBZ54717.1 - 1.1e-26 91.6 23.9 3.4e-07 29.8 0.0 10.8 11 1 0 11 11 11 5 WD domain, G-beta repeat Utp13 PF08625.6 CBZ54717.1 - 2e-15 56.6 0.0 3.9e-15 55.7 0.0 1.4 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain Nup160 PF11715.3 CBZ54717.1 - 0.015 13.4 2.5 0.06 11.4 0.8 2.6 2 1 0 2 2 2 0 Nucleoporin Nup120/160 CDC45 PF02724.9 CBZ54717.1 - 1.5 6.7 17.8 2.3 6.1 12.3 1.2 1 0 0 1 1 1 0 CDC45-like protein DKCLD PF08068.7 CBZ54718.1 - 1.3e-28 98.6 0.0 5.2e-28 96.7 0.0 2.1 1 0 0 1 1 1 1 DKCLD (NUC011) domain TruB_N PF01509.13 CBZ54718.1 - 1.6e-24 86.7 0.1 1.8e-21 76.8 0.1 3.4 1 1 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) PUA PF01472.15 CBZ54718.1 - 1.2e-20 72.9 1.2 2.2e-20 72.1 0.8 1.5 1 0 0 1 1 1 1 PUA domain Dopey_N PF04118.9 CBZ54720.1 - 2.7e-84 282.5 0.0 7.7e-84 281.0 0.0 1.7 2 0 0 2 2 2 1 Dopey, N-terminal Bromodomain PF00439.20 CBZ54721.1 - 1.5e-13 50.4 0.0 2.8e-13 49.5 0.0 1.4 1 0 0 1 1 1 1 Bromodomain Baculo_p74_N PF08404.5 CBZ54721.1 - 0.78 8.4 0.1 1.3 7.7 0.1 1.2 1 0 0 1 1 1 0 Baculoviridae P74 N-terminal PPDK_N PF01326.14 CBZ54723.1 - 1.2e-28 100.0 0.0 6.7e-27 94.3 0.0 3.5 1 1 0 1 1 1 1 Pyruvate phosphate dikinase, PEP/pyruvate binding domain GTP_EFTU PF00009.22 CBZ54724.1 - 1.5e-33 115.8 0.0 1.4e-32 112.6 0.0 2.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 CBZ54724.1 - 3.7e-20 71.8 0.1 9.3e-20 70.5 0.1 1.7 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.20 CBZ54724.1 - 4.4e-14 52.3 2.6 1.8e-08 34.3 0.1 3.3 2 0 0 2 2 2 2 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.1 CBZ54724.1 - 3.8e-08 32.8 0.1 1.1e-07 31.3 0.1 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.18 CBZ54724.1 - 3e-06 27.1 0.0 1.3e-05 25.1 0.0 2.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase PAPS_reduct PF01507.14 CBZ54725.1 - 8.6e-18 64.7 0.2 5.5e-12 45.8 0.0 3.4 2 1 0 2 2 2 2 Phosphoadenosine phosphosulfate reductase family DJ-1_PfpI PF01965.19 CBZ54726.1 - 5e-27 94.1 0.1 6.6e-27 93.7 0.1 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family DUF4066 PF13278.1 CBZ54726.1 - 1.6e-11 43.7 0.0 2.1e-11 43.3 0.0 1.1 1 0 0 1 1 1 1 Putative amidotransferase Laminin_G_3 PF13385.1 CBZ54727.1 - 1.7e-17 64.0 1.6 1.7e-09 38.1 0.1 3.4 3 0 0 3 3 3 2 Concanavalin A-like lectin/glucanases superfamily GCC2_GCC3 PF07699.8 CBZ54727.1 - 1.3e-05 24.6 9.4 0.00054 19.4 0.2 3.4 2 1 1 3 3 3 2 GCC2 and GCC3 DnaJ PF00226.26 CBZ54731.1 - 4.4e-07 29.5 0.0 7.9e-07 28.7 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain Dehalogenase PF13486.1 CBZ54732.1 - 0.13 11.7 0.8 0.21 11.0 0.6 1.4 1 0 0 1 1 1 0 Reductive dehalogenase subunit YchF-GTPase_C PF06071.8 CBZ54733.1 - 1.7e-40 136.6 1.5 2.6e-40 136.0 0.4 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.18 CBZ54733.1 - 1.7e-17 63.4 0.0 8e-17 61.2 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 CBZ54733.1 - 1.6e-06 27.4 0.0 4e-06 26.2 0.0 1.6 2 0 0 2 2 2 1 Ferrous iron transport protein B AAA_17 PF13207.1 CBZ54733.1 - 0.0023 18.7 0.0 0.025 15.4 0.0 2.6 1 1 0 1 1 1 1 AAA domain AAA PF00004.24 CBZ54733.1 - 0.0061 16.7 0.0 0.2 11.8 0.0 2.4 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) TGS PF02824.16 CBZ54733.1 - 0.03 14.1 0.0 0.079 12.8 0.0 1.7 1 0 0 1 1 1 0 TGS domain MobB PF03205.9 CBZ54733.1 - 0.031 13.9 0.0 1 9.0 0.0 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B ArgK PF03308.11 CBZ54733.1 - 0.1 11.3 0.1 0.33 9.6 0.0 1.8 2 0 0 2 2 2 0 ArgK protein AAA_14 PF13173.1 CBZ54733.1 - 0.12 12.2 0.0 0.39 10.6 0.0 2.0 1 1 0 1 1 1 0 AAA domain ACPS PF01648.15 CBZ54736.1 - 5.4e-08 32.6 0.1 4e-07 29.8 0.0 2.5 2 1 0 2 2 2 1 4'-phosphopantetheinyl transferase superfamily Kelch_2 PF07646.10 CBZ54736.1 - 0.12 12.1 0.0 0.31 10.8 0.0 1.7 1 0 0 1 1 1 0 Kelch motif Peptidase_C48 PF02902.14 CBZ54737.1 - 7.8e-38 130.2 0.6 1.2e-37 129.6 0.4 1.2 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Rep_fac-A_3 PF08661.6 CBZ54738.1 - 3.2e-08 33.4 0.0 3.9e-08 33.1 0.0 1.1 1 0 0 1 1 1 1 Replication factor A protein 3 Peptidase_M16_C PF05193.16 CBZ54739.1 - 8e-09 35.4 0.0 1.9e-06 27.6 0.0 2.9 3 0 0 3 3 3 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 CBZ54739.1 - 3.1e-06 27.0 0.0 1e-05 25.3 0.0 1.9 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Ank_5 PF13857.1 CBZ54740.1 - 1e-08 35.1 0.8 4.3e-08 33.1 0.5 2.0 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 CBZ54740.1 - 1.6e-05 25.1 0.1 4.6e-05 23.6 0.1 1.7 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.25 CBZ54740.1 - 0.0001 21.9 0.7 0.00049 19.7 0.3 2.3 2 0 0 2 2 2 1 Ankyrin repeat Ank_3 PF13606.1 CBZ54740.1 - 0.0061 16.6 0.1 0.016 15.4 0.1 1.7 1 0 0 1 1 1 1 Ankyrin repeat Ank_4 PF13637.1 CBZ54740.1 - 0.038 14.5 0.1 0.16 12.5 0.1 2.1 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Tfb2 PF03849.9 CBZ54742.1 - 2.3e-38 131.7 0.0 6.4e-25 87.5 0.0 4.1 4 0 0 4 4 4 3 Transcription factor Tfb2 Helicase_C_3 PF13625.1 CBZ54742.1 - 5.7e-07 29.3 0.1 1.3e-06 28.1 0.1 1.6 1 1 0 1 1 1 1 Helicase conserved C-terminal domain DnaJ PF00226.26 CBZ54743.1 - 6.2e-28 96.3 0.7 1.1e-27 95.4 0.5 1.5 1 0 0 1 1 1 1 DnaJ domain DUF3439 PF11921.3 CBZ54746.1 - 0.018 14.7 11.8 0.048 13.4 8.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Mucin PF01456.12 CBZ54746.1 - 0.24 11.1 18.5 0.017 14.8 7.8 2.5 2 0 0 2 2 2 0 Mucin-like glycoprotein Dicty_REP PF05086.7 CBZ54746.1 - 2.7 5.6 5.1 3.9 5.1 3.5 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein TPR_11 PF13414.1 CBZ54747.1 - 5.6e-18 64.3 1.4 1e-14 53.9 1.6 2.8 2 0 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 CBZ54747.1 - 9.1e-13 47.0 5.5 0.00036 20.2 0.6 4.5 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.23 CBZ54747.1 - 8.2e-11 41.0 2.7 0.00012 21.5 0.4 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.1 CBZ54747.1 - 9.6e-08 31.2 1.8 0.072 12.9 0.4 4.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.1 CBZ54747.1 - 2.2e-07 30.7 4.3 2.5e-06 27.3 1.0 3.2 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 CBZ54747.1 - 5.9e-06 26.7 1.4 0.0028 18.3 0.1 2.9 2 1 1 3 3 2 2 Tetratricopeptide repeat Apc3 PF12895.2 CBZ54747.1 - 7.7e-05 22.7 0.1 0.00025 21.1 0.0 2.0 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 CBZ54747.1 - 0.01 15.6 0.0 0.17 11.7 0.0 2.5 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 CBZ54747.1 - 0.014 15.9 4.8 2 9.2 0.0 4.5 4 1 1 5 5 4 0 Tetratricopeptide repeat TPR_7 PF13176.1 CBZ54747.1 - 0.022 14.5 5.5 0.13 12.0 0.1 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.1 CBZ54747.1 - 0.043 14.1 0.1 0.62 10.4 0.2 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.1 CBZ54747.1 - 0.081 12.8 1.5 5.7 7.0 0.1 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat RPN7 PF10602.4 CBZ54747.1 - 0.11 11.9 0.4 0.28 10.5 0.3 1.6 1 0 0 1 1 1 0 26S proteasome subunit RPN7 TPR_6 PF13174.1 CBZ54747.1 - 0.11 12.9 4.6 35 5.1 0.0 4.0 4 0 0 4 4 3 0 Tetratricopeptide repeat Prp19_bind PF06991.6 CBZ54748.1 - 6.2e-37 127.3 38.6 6.2e-37 127.3 26.8 2.5 1 1 2 3 3 3 1 Splicing factor, Prp19-binding domain DUF2522 PF10747.4 CBZ54749.1 - 4.5 7.3 0.0 8.2 6.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2522) TRAPPC-Trs85 PF12739.2 CBZ54750.1 - 7.3e-90 301.5 13.4 4.5e-89 298.9 9.3 2.3 1 1 0 1 1 1 1 ER-Golgi trafficking TRAPP I complex 85 kDa subunit SNAP PF14938.1 CBZ54750.1 - 0.02 14.0 2.9 0.051 12.7 0.1 2.1 2 0 0 2 2 2 0 Soluble NSF attachment protein, SNAP 2OG-FeII_Oxy_3 PF13640.1 CBZ54751.1 - 1.2e-08 35.3 0.0 2.7e-08 34.2 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily HGD-D PF06050.8 CBZ54751.1 - 0.014 14.2 0.0 0.024 13.4 0.0 1.3 1 0 0 1 1 1 0 2-hydroxyglutaryl-CoA dehydratase, D-component Amido_AtzD_TrzD PF09663.5 CBZ54752.1 - 0.041 12.4 0.0 0.89 8.0 0.0 2.1 2 0 0 2 2 2 0 Amidohydrolase ring-opening protein (Amido_AtzD_TrzD) Ycf1 PF05758.7 CBZ54752.1 - 1.3 6.6 0.0 2.4 5.7 0.0 1.3 1 1 0 1 1 1 0 Ycf1 AOX PF01786.12 CBZ54754.1 - 0.15 11.4 0.1 3.6 6.9 0.0 2.6 2 0 0 2 2 2 0 Alternative oxidase 2-Hacid_dh_C PF02826.14 CBZ54755.1 - 2.1e-36 124.7 0.0 5.8e-36 123.3 0.0 1.7 1 1 1 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 CBZ54755.1 - 0.0043 16.5 0.0 0.54 9.7 0.0 2.4 2 1 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain Ras PF00071.17 CBZ54756.1 - 4.6e-67 224.4 0.5 5.3e-67 224.2 0.4 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CBZ54756.1 - 3e-21 76.1 0.0 4.4e-21 75.5 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CBZ54756.1 - 1.4e-16 60.2 0.1 1.9e-16 59.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 CBZ54756.1 - 9.1e-07 28.2 0.1 1.6e-06 27.4 0.0 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 CBZ54756.1 - 5.4e-05 22.7 0.2 0.00011 21.7 0.1 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 CBZ54756.1 - 8.7e-05 22.4 0.0 0.00014 21.8 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 CBZ54756.1 - 9.3e-05 21.7 0.0 0.00013 21.2 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit DUF258 PF03193.11 CBZ54756.1 - 0.00076 18.7 0.0 0.002 17.3 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 CBZ54756.1 - 0.0038 17.3 0.0 0.0051 16.9 0.0 1.4 1 1 0 1 1 1 1 AAA domain PduV-EutP PF10662.4 CBZ54756.1 - 0.017 14.6 0.0 0.074 12.5 0.0 2.0 1 1 1 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_5 PF07728.9 CBZ54756.1 - 0.036 13.7 0.0 0.068 12.8 0.0 1.8 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 CBZ54756.1 - 0.037 13.9 0.0 0.057 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.1 CBZ54756.1 - 0.038 13.5 0.0 0.11 12.0 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_10 PF12846.2 CBZ54756.1 - 0.092 12.1 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain FeoB_N PF02421.13 CBZ54756.1 - 0.11 11.8 0.0 0.42 9.8 0.0 1.8 1 1 0 1 1 1 0 Ferrous iron transport protein B G-alpha PF00503.15 CBZ54756.1 - 0.66 8.6 4.5 5.2 5.6 0.5 2.7 1 1 1 2 2 2 0 G-protein alpha subunit NUDIX PF00293.23 CBZ54757.1 - 3.6e-20 71.9 0.1 4.6e-20 71.6 0.1 1.2 1 0 0 1 1 1 1 NUDIX domain Phage_min_tail PF05939.8 CBZ54757.1 - 0.07 13.0 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 Phage minor tail protein MAM33 PF02330.11 CBZ54758.1 - 5.9e-21 75.1 1.3 8e-16 58.4 0.1 2.1 1 1 1 2 2 2 2 Mitochondrial glycoprotein FERM_C PF09380.5 CBZ54758.1 - 0.025 14.8 0.0 0.07 13.3 0.0 1.7 1 1 0 1 1 1 0 FERM C-terminal PH-like domain FAM195 PF14799.1 CBZ54758.1 - 0.086 12.7 0.3 0.17 11.7 0.2 1.5 1 0 0 1 1 1 0 FAM195 family PRA1 PF03208.14 CBZ54760.1 - 9.9e-23 80.1 1.5 1.4e-22 79.7 1.0 1.1 1 0 0 1 1 1 1 PRA1 family protein DUF3488 PF11992.3 CBZ54760.1 - 4.1 5.9 7.0 5.6 5.5 4.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3488) ATP_synt_I PF03899.10 CBZ54760.1 - 4.8 7.4 9.5 0.29 11.3 1.2 2.4 3 0 0 3 3 3 0 ATP synthase I chain G-patch PF01585.18 CBZ54761.1 - 1.3e-14 53.6 0.8 2.5e-14 52.7 0.5 1.5 1 0 0 1 1 1 1 G-patch domain RRM_1 PF00076.17 CBZ54761.1 - 0.00013 21.5 0.1 0.00024 20.6 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) G-patch_2 PF12656.2 CBZ54761.1 - 0.0014 18.3 0.3 0.0055 16.5 0.2 2.0 1 0 0 1 1 1 1 DExH-box splicing factor binding site RRM_5 PF13893.1 CBZ54761.1 - 0.0035 17.1 0.2 0.012 15.4 0.0 2.0 2 1 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PMD PF10536.4 CBZ54761.1 - 0.11 11.4 0.1 0.17 10.8 0.1 1.2 1 0 0 1 1 1 0 Plant mobile domain RRM_6 PF14259.1 CBZ54761.1 - 0.15 12.0 0.0 0.37 10.8 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) YodL PF14191.1 CBZ54761.1 - 0.18 12.3 0.1 0.38 11.2 0.1 1.5 1 0 0 1 1 1 0 YodL-like Xpo1 PF08389.7 CBZ54762.1 - 6.2e-09 35.9 0.0 3.5e-08 33.4 0.0 2.4 1 0 0 1 1 1 1 Exportin 1-like protein AP2 PF00847.15 CBZ54763.1 - 3.9e-28 97.3 13.5 1.3e-09 38.0 0.2 3.8 3 0 0 3 3 3 3 AP2 domain Nuc-transf PF10127.4 CBZ54763.1 - 0.89 8.8 0.0 1.6 8.0 0.0 1.3 1 0 0 1 1 1 0 Predicted nucleotidyltransferase DXPR_C PF13288.1 CBZ54764.1 - 1.1e-41 141.6 0.0 1.6e-41 141.1 0.0 1.2 1 0 0 1 1 1 1 DXP reductoisomerase C-terminal domain DXP_reductoisom PF02670.11 CBZ54764.1 - 5.4e-40 136.9 0.0 8.2e-40 136.3 0.0 1.3 1 0 0 1 1 1 1 1-deoxy-D-xylulose 5-phosphate reductoisomerase DXP_redisom_C PF08436.7 CBZ54764.1 - 5.1e-35 119.2 0.0 1.1e-34 118.1 0.0 1.6 1 0 0 1 1 1 1 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal NAD_binding_3 PF03447.11 CBZ54764.1 - 0.035 14.5 0.1 0.15 12.4 0.1 2.1 1 1 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain Ribosomal_L9_N PF01281.14 CBZ54765.1 - 5.8e-12 44.6 0.0 1.4e-11 43.4 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein L9, N-terminal domain GWT1 PF06423.7 CBZ54769.1 - 1.2e-17 64.3 0.6 1.2e-17 64.3 0.4 2.4 3 0 0 3 3 3 1 GWT1 MCM PF00493.18 CBZ54774.1 - 1.9e-119 398.3 0.0 5.3e-109 364.0 0.0 2.2 2 0 0 2 2 2 2 MCM2/3/5 family MCM_N PF14551.1 CBZ54774.1 - 6.7e-16 58.8 0.0 2.4e-15 57.0 0.0 2.0 1 1 1 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 CBZ54774.1 - 4.7e-08 32.4 0.1 1.3e-05 24.5 0.0 2.6 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 CBZ54774.1 - 0.00026 20.7 0.0 0.00074 19.2 0.0 1.9 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.21 CBZ54774.1 - 0.00045 19.7 0.0 0.0021 17.5 0.0 2.0 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_3 PF07726.6 CBZ54774.1 - 0.0019 17.8 0.0 0.011 15.3 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA PF00004.24 CBZ54774.1 - 0.015 15.4 0.0 0.052 13.7 0.0 2.0 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 CBZ54774.1 - 0.072 13.2 0.1 0.49 10.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain NTP_transf_2 PF01909.18 CBZ54776.1 - 0.0037 17.5 0.1 0.0073 16.6 0.1 1.4 1 0 0 1 1 1 1 Nucleotidyltransferase domain PAP_assoc PF03828.14 CBZ54776.1 - 0.03 14.2 0.5 0.094 12.6 0.2 1.9 2 0 0 2 2 2 0 Cid1 family poly A polymerase Enkurin PF13864.1 CBZ54776.1 - 0.18 12.0 1.0 0.39 10.9 0.7 1.5 1 0 0 1 1 1 0 Calmodulin-binding Phage_C PF12025.3 CBZ54776.1 - 3.4 7.6 0.0 7.3 6.6 0.0 1.4 1 0 0 1 1 1 0 Phage protein C PrsW-protease PF13367.1 CBZ54777.1 - 9.6e-13 47.7 14.1 1.9e-11 43.5 6.3 3.5 2 1 0 2 2 2 2 Protease prsW family MRP-L20 PF12824.2 CBZ54778.1 - 0.075 12.9 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 Mitochondrial ribosomal protein subunit L20 OB_NTP_bind PF07717.11 CBZ54779.1 - 2.7e-10 40.0 0.0 9.1e-10 38.3 0.0 1.9 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 CBZ54779.1 - 9.1e-07 28.8 0.0 9.1e-07 28.8 0.0 2.5 2 0 0 2 2 2 1 Helicase associated domain (HA2) PhoU PF01895.14 CBZ54779.1 - 0.29 11.6 0.7 0.77 10.2 0.5 1.6 1 0 0 1 1 1 0 PhoU domain SAPS PF04499.10 CBZ54779.1 - 0.91 8.0 11.0 0.38 9.3 0.4 2.6 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein HEAT_2 PF13646.1 CBZ54780.1 - 0.00068 19.8 21.6 0.0021 18.3 0.8 5.9 5 1 1 6 6 6 2 HEAT repeats HEAT PF02985.17 CBZ54780.1 - 0.0019 18.1 6.2 0.19 11.9 0.0 6.0 7 0 0 7 7 7 1 HEAT repeat HEAT_EZ PF13513.1 CBZ54780.1 - 0.0025 18.2 0.7 0.0025 18.2 0.5 9.4 7 3 4 11 11 11 1 HEAT-like repeat V-ATPase_H_N PF03224.9 CBZ54780.1 - 0.026 13.6 0.0 0.35 9.9 0.0 2.2 2 0 0 2 2 2 0 V-ATPase subunit H Cnd1 PF12717.2 CBZ54780.1 - 0.034 13.9 0.0 0.12 12.2 0.0 1.9 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 CEP44 PF15007.1 CBZ54780.1 - 0.094 12.4 0.0 0.22 11.2 0.0 1.5 1 0 0 1 1 1 0 Centrosomal spindle body, CEP44 UME PF08064.8 CBZ54780.1 - 0.14 12.1 0.4 3.4 7.6 0.0 3.4 4 0 0 4 4 4 0 UME (NUC010) domain Cse1 PF08506.5 CBZ54780.1 - 0.29 9.6 0.0 0.59 8.6 0.0 1.4 1 0 0 1 1 1 0 Cse1 DUF3554 PF12074.3 CBZ54780.1 - 0.61 9.4 0.0 0.61 9.4 0.0 2.8 4 0 0 4 4 4 0 Domain of unknown function (DUF3554) Arf PF00025.16 CBZ54781.1 - 5.3e-63 211.3 0.0 5.9e-63 211.2 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 CBZ54781.1 - 5.1e-11 42.1 0.0 6.7e-11 41.7 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Miro PF08477.8 CBZ54781.1 - 3.5e-10 40.4 0.0 4.8e-10 39.9 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein G-alpha PF00503.15 CBZ54781.1 - 4.5e-10 38.7 0.2 8.1e-07 28.0 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.17 CBZ54781.1 - 1.5e-08 34.2 0.0 1.8e-08 33.9 0.0 1.1 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.18 CBZ54781.1 - 1.8e-06 27.8 0.0 2.6e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 CBZ54781.1 - 2.8e-06 26.6 0.0 3.5e-06 26.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 CBZ54781.1 - 4.5e-05 22.9 0.1 0.0011 18.3 0.0 2.0 1 1 0 2 2 2 1 Elongation factor Tu GTP binding domain CENP-M PF11111.3 CBZ54781.1 - 0.011 15.0 0.0 0.023 13.9 0.0 1.5 2 0 0 2 2 2 0 Centromere protein M (CENP-M) PduV-EutP PF10662.4 CBZ54781.1 - 0.037 13.5 0.0 0.085 12.3 0.0 1.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation cobW PF02492.14 CBZ54781.1 - 0.091 12.1 0.0 4.4 6.7 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Fer2 PF00111.22 CBZ54782.1 - 4.9e-19 67.8 1.3 7.6e-19 67.2 0.9 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer2_4 PF13510.1 CBZ54782.1 - 0.12 12.2 0.0 0.27 11.0 0.0 1.6 1 0 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain Nop14 PF04147.7 CBZ54783.1 - 0.0001 20.4 18.3 0.0001 20.4 12.7 4.3 4 1 0 4 4 4 1 Nop14-like family FBPase_3 PF01950.11 CBZ54783.1 - 3.9 6.3 0.0 6.2 5.7 0.0 1.1 1 0 0 1 1 1 0 Fructose-1,6-bisphosphatase ATP_bind_1 PF03029.12 CBZ54784.1 - 5e-35 121.1 3.2 8.2e-33 113.9 2.2 2.2 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein TyeA PF09059.5 CBZ54784.1 - 1 9.3 5.5 5 7.1 0.0 3.3 3 1 0 4 4 4 0 TyeA ATP_bind_3 PF01171.15 CBZ54785.1 - 1.9e-23 82.8 0.0 9.5e-18 64.3 0.0 3.3 3 0 0 3 3 3 3 PP-loop family Clat_adaptor_s PF01217.15 CBZ54786.1 - 7.9e-46 155.3 0.6 9e-46 155.1 0.4 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain NUFIP1 PF10453.4 CBZ54787.1 - 0.034 13.6 0.1 0.059 12.8 0.1 1.3 1 0 0 1 1 1 0 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) DUF2430 PF10353.4 CBZ54787.1 - 0.12 12.5 0.0 0.29 11.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2430) AP2 PF00847.15 CBZ54788.1 - 3.6e-10 39.8 2.6 1.1e-09 38.2 1.8 1.8 1 0 0 1 1 1 1 AP2 domain Metallophos PF00149.23 CBZ54790.1 - 3.1e-36 124.6 0.0 4.6e-36 124.0 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Clathrin PF00637.15 CBZ54791.1 - 1.5e-07 31.1 1.9 0.076 12.6 0.0 4.4 3 1 1 4 4 4 3 Region in Clathrin and VPS TPR_11 PF13414.1 CBZ54791.1 - 8.9e-06 25.2 4.9 0.41 10.3 0.6 4.6 3 2 0 3 3 3 2 TPR repeat TPR_2 PF07719.12 CBZ54791.1 - 4.6e-05 23.0 12.0 0.32 11.0 0.6 5.4 6 0 0 6 6 4 2 Tetratricopeptide repeat PPR PF01535.15 CBZ54791.1 - 0.0016 18.2 0.9 3.3 7.9 0.0 5.6 6 0 0 6 6 6 1 PPR repeat Nic96 PF04097.9 CBZ54791.1 - 0.003 15.7 4.8 0.5 8.4 0.1 3.1 1 1 2 3 3 3 3 Nup93/Nic96 TPR_14 PF13428.1 CBZ54791.1 - 0.0039 17.6 11.2 12 6.8 0.8 6.3 7 1 0 7 7 5 0 Tetratricopeptide repeat TPR_1 PF00515.23 CBZ54791.1 - 0.0062 16.0 7.3 1.8 8.2 0.1 5.1 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.1 CBZ54791.1 - 0.05 13.4 12.8 1.3 9.0 0.1 5.8 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_12 PF13424.1 CBZ54791.1 - 0.36 10.8 13.9 18 5.3 0.1 5.5 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_10 PF13374.1 CBZ54791.1 - 0.46 10.5 8.8 20 5.2 0.5 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat MIT PF04212.13 CBZ54791.1 - 0.57 10.1 9.3 1.7 8.5 0.0 3.6 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain Apc3 PF12895.2 CBZ54791.1 - 2.6 8.2 14.5 2.7 8.2 0.3 4.6 4 2 1 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 Coatomer_WDAD PF04053.9 CBZ54791.1 - 3.6 6.2 3.6 5 5.8 0.1 2.7 4 0 0 4 4 4 0 Coatomer WD associated region TPR_16 PF13432.1 CBZ54791.1 - 5.5 7.7 14.4 45 4.8 0.0 5.5 5 0 0 5 5 5 0 Tetratricopeptide repeat WXG100 PF06013.7 CBZ54793.1 - 0.16 11.9 1.3 1.2 9.2 0.2 2.6 2 0 0 2 2 2 0 Proteins of 100 residues with WXG RRM_6 PF14259.1 CBZ54794.1 - 3.2e-15 55.8 0.1 1.7e-08 34.3 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CBZ54794.1 - 6e-15 54.6 0.2 9.4e-08 31.5 0.0 2.9 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBZ54794.1 - 1.2e-08 34.6 0.2 1.1e-05 25.1 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4339 PF14237.1 CBZ54794.1 - 1.3e-05 24.6 0.0 3.1e-05 23.4 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4339) TPK_catalytic PF04263.11 CBZ54795.1 - 9.7e-18 63.9 0.0 1.4e-17 63.4 0.0 1.2 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, catalytic domain CPSase_L_D2 PF02786.12 CBZ54796.1 - 8e-109 361.8 0.3 9.5e-81 270.1 0.1 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_sm_chain PF00988.17 CBZ54796.1 - 6e-46 155.1 0.0 1.2e-45 154.1 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.23 CBZ54796.1 - 3.2e-45 153.9 0.0 9e-45 152.4 0.0 1.8 2 0 0 2 2 2 1 Glutamine amidotransferase class-I CPSase_L_D3 PF02787.14 CBZ54796.1 - 1.6e-40 137.7 0.0 8.7e-40 135.3 0.0 2.2 2 0 0 2 2 2 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain CPSase_L_chain PF00289.17 CBZ54796.1 - 1.4e-37 128.1 0.0 9.9e-18 64.2 0.0 3.0 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, N-terminal domain ATP-grasp_4 PF13535.1 CBZ54796.1 - 1.4e-33 116.2 1.9 3.5e-19 69.2 0.1 2.4 2 0 0 2 2 2 2 ATP-grasp domain ATPgrasp_Ter PF15632.1 CBZ54796.1 - 1.1e-26 93.3 0.6 3.2e-16 58.9 0.0 3.4 3 0 0 3 3 3 3 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.17 CBZ54796.1 - 4.5e-16 58.6 3.6 7.7e-08 31.8 0.0 2.6 3 0 0 3 3 3 2 ATP-grasp domain Dala_Dala_lig_C PF07478.8 CBZ54796.1 - 3.3e-12 46.2 1.9 4.4e-05 22.9 0.1 2.9 2 2 0 2 2 2 2 D-ala D-ala ligase C-terminus MGS PF02142.17 CBZ54796.1 - 1e-07 31.8 0.1 9.9e-06 25.4 0.0 3.1 2 0 0 2 2 2 1 MGS-like domain Peptidase_C26 PF07722.8 CBZ54796.1 - 2e-06 27.4 0.0 2.8e-05 23.6 0.0 2.3 1 1 0 1 1 1 1 Peptidase C26 ATP-grasp_3 PF02655.9 CBZ54796.1 - 3.5e-06 26.9 1.2 0.024 14.4 0.0 3.1 3 0 0 3 3 3 2 ATP-grasp domain GARS_A PF01071.14 CBZ54796.1 - 0.00025 20.6 0.4 0.024 14.1 0.0 2.6 2 1 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain TrkA_N PF02254.13 CBZ54796.1 - 0.0023 17.8 0.1 2.6 8.0 0.0 3.2 3 0 0 3 3 3 1 TrkA-N domain DJ-1_PfpI PF01965.19 CBZ54796.1 - 0.018 14.5 0.1 0.087 12.2 0.0 2.1 2 0 0 2 2 2 0 DJ-1/PfpI family ATP-grasp_5 PF13549.1 CBZ54796.1 - 0.029 13.5 0.0 0.097 11.8 0.1 1.7 2 0 0 2 2 2 0 ATP-grasp domain Fer2_3 PF13085.1 CBZ54797.1 - 5.7e-33 113.0 0.1 1.2e-32 111.9 0.0 1.6 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.1 CBZ54797.1 - 3e-10 40.2 4.7 3e-10 40.2 3.2 2.5 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_8 PF13183.1 CBZ54797.1 - 2.9e-08 33.5 4.6 2.9e-08 33.5 3.2 2.3 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_18 PF13746.1 CBZ54797.1 - 2.9e-06 27.6 0.9 2.9e-06 27.6 0.6 2.8 2 2 1 3 3 3 2 4Fe-4S dicluster domain Fer2 PF00111.22 CBZ54797.1 - 0.0026 17.4 0.9 0.0026 17.4 0.7 2.3 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_9 PF13187.1 CBZ54797.1 - 0.0031 17.7 12.8 0.02 15.1 0.6 3.4 3 1 1 4 4 4 2 4Fe-4S dicluster domain Fer4_7 PF12838.2 CBZ54797.1 - 3.7 7.9 19.0 0.044 14.1 5.4 3.2 2 2 1 3 3 3 0 4Fe-4S dicluster domain Fer4_10 PF13237.1 CBZ54797.1 - 6 6.7 21.0 0.036 13.8 6.1 3.0 2 2 0 2 2 2 0 4Fe-4S dicluster domain Saccharop_dh PF03435.13 CBZ54798.1 - 1e-16 60.9 0.1 1.4e-16 60.5 0.1 1.1 1 0 0 1 1 1 1 Saccharopine dehydrogenase NAD_binding_10 PF13460.1 CBZ54798.1 - 0.035 14.1 0.0 0.16 11.9 0.0 2.0 1 1 0 1 1 1 0 NADH(P)-binding NmrA PF05368.8 CBZ54798.1 - 0.1 11.8 0.0 0.31 10.2 0.0 1.7 1 1 0 1 1 1 0 NmrA-like family AP2 PF00847.15 CBZ54800.1 - 0.034 14.3 2.4 0.075 13.1 1.6 1.6 1 0 0 1 1 1 0 AP2 domain DUF948 PF06103.6 CBZ54802.1 - 0.17 11.7 3.0 0.21 11.4 1.3 1.7 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Chorion_S16 PF05836.7 CBZ54804.1 - 6.4 6.7 7.0 22 4.9 0.5 2.8 2 0 0 2 2 2 0 Chorion protein S16 zf-Tim10_DDP PF02953.10 CBZ54805.1 - 2.2e-20 71.6 0.1 2.5e-20 71.5 0.0 1.0 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF1450 PF07293.6 CBZ54805.1 - 0.14 12.1 0.2 0.21 11.5 0.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1450) RRM_1 PF00076.17 CBZ54806.1 - 4e-15 55.2 0.0 7.9e-15 54.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBZ54806.1 - 2.9e-14 52.8 0.0 5.8e-14 51.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBZ54806.1 - 2.5e-10 40.0 0.1 4.4e-10 39.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Brucella_OMP2 PF05244.6 CBZ54806.1 - 0.17 10.9 0.3 0.26 10.4 0.2 1.2 1 0 0 1 1 1 0 Brucella outer membrane protein 2 DPCD PF14913.1 CBZ54807.1 - 7.9e-53 178.4 0.0 1e-52 178.0 0.0 1.1 1 0 0 1 1 1 1 DPCD protein family Synaptobrevin PF00957.16 CBZ54808.1 - 4.3e-17 61.4 1.4 6.8e-17 60.8 1.0 1.3 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.1 CBZ54808.1 - 9.5e-07 28.2 0.0 1.6e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain V-ATPase_H_N PF03224.9 CBZ54809.1 - 0.022 13.8 0.2 0.027 13.6 0.2 1.1 1 0 0 1 1 1 0 V-ATPase subunit H Pex14_N PF04695.8 CBZ54809.1 - 0.068 13.2 0.7 4.3 7.3 0.0 2.6 2 1 1 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Uteroglobin PF01099.12 CBZ54809.1 - 0.36 10.6 2.1 8.2 6.3 0.0 3.2 3 1 1 4 4 4 0 Uteroglobin family WWE PF02825.15 CBZ54810.1 - 1.3e-09 37.2 3.8 9.7e-05 21.7 0.2 3.2 2 1 0 2 2 2 2 WWE domain zf-RING_2 PF13639.1 CBZ54810.1 - 5.1e-08 32.6 6.4 1.3e-06 28.1 4.4 2.9 1 1 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 CBZ54810.1 - 6.6e-08 32.5 0.4 6.6e-08 32.5 0.3 1.9 2 0 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 CBZ54810.1 - 2.7e-05 23.7 3.2 9.6e-05 21.9 2.2 2.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) PHD PF00628.24 CBZ54810.1 - 0.00057 19.5 0.2 0.0026 17.4 0.2 2.2 1 0 0 1 1 1 1 PHD-finger zf-C3HC4_2 PF13923.1 CBZ54810.1 - 0.0017 18.3 0.6 0.0017 18.3 0.4 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBZ54810.1 - 0.0027 17.4 1.6 0.0081 15.8 1.1 1.9 1 1 0 1 1 1 1 zinc-RING finger domain zf-Nse PF11789.3 CBZ54810.1 - 0.0062 16.0 0.3 0.019 14.4 0.2 1.8 1 1 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-Apc11 PF12861.2 CBZ54810.1 - 0.25 11.2 3.0 1.2 8.9 2.1 2.2 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.1 CBZ54810.1 - 9.8 6.1 9.6 0.34 10.8 0.3 2.5 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING MIP PF00230.15 CBZ54811.1 - 5.5e-21 75.0 16.4 8.8e-21 74.4 11.4 1.2 1 0 0 1 1 1 1 Major intrinsic protein Rick_17kDa_Anti PF05433.10 CBZ54811.1 - 9.2 6.0 10.0 6.8 6.4 1.7 2.9 2 0 0 2 2 2 0 Glycine zipper 2TM domain Ribosomal_S24e PF01282.14 CBZ54812.1 - 4.2e-27 93.7 0.0 6.5e-27 93.1 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S24e Ribosomal_L1 PF00687.16 CBZ54813.1 - 2.7e-48 164.2 2.3 3.2e-48 163.9 1.6 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family TetR PF13972.1 CBZ54813.1 - 0.095 12.1 0.2 0.2 11.1 0.1 1.6 2 0 0 2 2 2 0 Bacterial transcriptional repressor A_deaminase PF00962.17 CBZ54814.1 - 4.5e-53 180.3 0.0 1.2e-46 159.2 0.0 2.9 3 0 0 3 3 3 3 Adenosine/AMP deaminase MFS_1 PF07690.11 CBZ54815.1 - 6.1e-17 61.3 19.9 6.1e-17 61.3 13.8 2.3 2 1 0 3 3 3 1 Major Facilitator Superfamily DUF4006 PF13179.1 CBZ54815.1 - 0.9 9.1 4.5 6.4 6.4 0.1 3.0 3 0 0 3 3 3 0 Family of unknown function (DUF4006) TPR_11 PF13414.1 CBZ54816.1 - 3.7e-08 32.8 0.8 1.3e-06 27.9 0.3 2.5 2 0 0 2 2 2 1 TPR repeat DUF4511 PF14974.1 CBZ54816.1 - 0.00035 20.2 0.0 0.0041 16.8 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4511) TPR_1 PF00515.23 CBZ54816.1 - 0.0043 16.6 0.5 0.58 9.8 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 CBZ54816.1 - 0.0056 17.3 4.0 0.026 15.1 0.1 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 CBZ54816.1 - 0.012 15.4 0.8 1.3 9.0 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.1 CBZ54816.1 - 0.013 15.8 1.1 0.056 13.7 0.1 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat Methyltransf_5 PF01795.14 CBZ54817.1 - 2.6e-62 210.8 0.0 2.1e-25 89.6 0.0 4.1 4 0 0 4 4 4 4 MraW methylase family Methyltransf_26 PF13659.1 CBZ54817.1 - 4.2e-05 23.5 0.0 0.036 14.0 0.0 2.7 2 1 0 2 2 2 2 Methyltransferase domain Methyltransf_18 PF12847.2 CBZ54817.1 - 8.1e-05 23.1 0.1 0.11 13.0 0.0 2.6 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_31 PF13847.1 CBZ54817.1 - 0.00037 20.0 0.0 0.41 10.2 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain MTS PF05175.9 CBZ54817.1 - 0.0014 18.0 0.1 1.1 8.5 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase small domain Methyltransf_11 PF08241.7 CBZ54817.1 - 0.0021 18.5 0.1 1.6 9.2 0.0 2.6 2 0 0 2 2 2 2 Methyltransferase domain PCMT PF01135.14 CBZ54817.1 - 0.14 11.7 0.0 0.35 10.3 0.0 1.6 2 0 0 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MEDS PF14417.1 CBZ54819.1 - 0.0042 16.1 0.0 0.0058 15.7 0.0 1.1 1 0 0 1 1 1 1 MEDS: MEthanogen/methylotroph, DcmR Sensory domain ATP-synt_DE PF00401.15 CBZ54819.1 - 4.5 7.2 8.8 0.96 9.3 2.2 2.1 2 0 0 2 2 2 0 ATP synthase, Delta/Epsilon chain, long alpha-helix domain Exo5 PF09810.4 CBZ54821.1 - 2.9e-66 223.9 0.0 5.1e-66 223.1 0.0 1.4 1 0 0 1 1 1 1 Exonuclease V - a 5' deoxyribonuclease PRMT5 PF05185.11 CBZ54822.1 - 5e-117 391.5 0.0 4.9e-87 292.7 0.0 3.0 3 0 0 3 3 3 3 PRMT5 arginine-N-methyltransferase ACDC PF14733.1 CBZ54823.1 - 1.2e-20 73.3 0.0 1.9e-20 72.7 0.0 1.3 1 0 0 1 1 1 1 AP2-coincident C-terminal AP2 PF00847.15 CBZ54823.1 - 1.9e-20 72.7 6.6 2.3e-10 40.4 0.5 2.3 2 0 0 2 2 2 2 AP2 domain Succ_DH_flav_C PF02910.15 CBZ54824.1 - 5e-46 155.7 1.3 7e-46 155.2 0.9 1.2 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term FAD_binding_2 PF00890.19 CBZ54824.1 - 3.5e-18 65.6 1.1 1.1e-17 63.9 0.1 1.9 2 0 0 2 2 2 1 FAD binding domain DUF4468 PF14730.1 CBZ54825.1 - 0.061 13.0 0.2 0.11 12.2 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4468) with TBP-like fold PagP PF07017.6 CBZ54825.1 - 0.068 12.4 2.7 0.085 12.1 1.9 1.1 1 0 0 1 1 1 0 Antimicrobial peptide resistance and lipid A acylation protein PagP zf-C3HC4_3 PF13920.1 CBZ54827.1 - 2.4e-08 33.4 5.8 2.4e-08 33.4 4.0 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CBZ54827.1 - 1.7e-07 30.9 10.5 1.7e-07 30.9 7.3 2.3 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4 PF00097.20 CBZ54827.1 - 2.5e-07 30.2 8.0 6.7e-07 28.8 5.6 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CBZ54827.1 - 5.3e-07 29.5 10.3 5.3e-07 29.5 7.2 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBZ54827.1 - 2.6e-06 27.0 6.2 2.6e-06 27.0 4.3 2.2 2 0 0 2 2 2 1 zinc-RING finger domain U-box PF04564.10 CBZ54827.1 - 2.9e-05 23.9 0.4 7.1e-05 22.6 0.0 1.8 2 0 0 2 2 2 1 U-box domain zf-RING_UBOX PF13445.1 CBZ54827.1 - 4.5e-05 23.0 6.8 0.00011 21.7 4.7 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_6 PF14835.1 CBZ54827.1 - 0.00046 19.9 2.8 0.0013 18.5 2.0 1.7 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-C3HC4_4 PF15227.1 CBZ54827.1 - 0.00091 19.0 11.2 0.00091 19.0 7.8 2.1 2 0 0 2 2 1 1 zinc finger of C3HC4-type, RING Peptidase_C97 PF05903.9 CBZ54827.1 - 0.044 13.5 0.1 0.081 12.7 0.1 1.3 1 0 0 1 1 1 0 PPPDE putative peptidase domain zf-rbx1 PF12678.2 CBZ54827.1 - 0.1 12.7 3.3 0.18 11.9 1.3 2.2 2 0 0 2 2 1 0 RING-H2 zinc finger Prok-RING_4 PF14447.1 CBZ54827.1 - 0.11 12.0 3.7 0.29 10.7 2.5 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Pkinase PF00069.20 CBZ54829.1 - 7.1e-52 176.1 0.0 1.2e-36 126.2 0.1 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ54829.1 - 2.4e-22 79.2 0.4 3.5e-15 55.7 0.2 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.9 CBZ54829.1 - 0.0001 21.4 0.3 0.0002 20.5 0.2 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CBZ54829.1 - 0.00041 20.1 0.3 0.015 15.0 0.0 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.1 CBZ54829.1 - 0.001 18.1 3.1 0.042 12.8 0.0 2.6 3 0 0 3 3 3 2 Kinase-like Seadorna_VP7 PF07387.6 CBZ54829.1 - 0.16 10.7 0.1 0.27 10.0 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 SAG PF04092.8 CBZ54830.1 - 4.1e-09 36.8 2.0 6.1e-09 36.3 1.4 1.3 1 0 0 1 1 1 1 SRS domain PI3_PI4_kinase PF00454.22 CBZ54832.1 - 4.5e-34 117.9 0.0 2.8e-33 115.3 0.0 2.0 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.15 CBZ54832.1 - 4.2e-17 61.9 0.0 3.3e-12 45.9 0.0 2.2 2 0 0 2 2 2 2 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3K_C2 PF00792.19 CBZ54832.1 - 0.0027 17.5 0.0 0.0086 15.8 0.0 1.8 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 DUF2269 PF10027.4 CBZ54832.1 - 0.17 11.6 0.0 0.37 10.5 0.0 1.5 1 0 0 1 1 1 0 Predicted integral membrane protein (DUF2269) Sec3_C PF09763.4 CBZ54832.1 - 3.5 5.6 3.4 8.1 4.4 2.3 1.5 1 0 0 1 1 1 0 Exocyst complex component Sec3 Ycf1 PF05758.7 CBZ54832.1 - 8.6 3.9 5.7 14 3.1 3.9 1.2 1 0 0 1 1 1 0 Ycf1 AAA_22 PF13401.1 CBZ54833.1 - 0.047 13.8 0.1 0.18 11.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.1 CBZ54833.1 - 0.1 12.5 0.0 0.1 12.5 0.0 2.3 2 1 1 3 3 3 0 AAA ATPase domain YEATS PF03366.11 CBZ54834.1 - 1e-22 79.6 0.0 1.8e-22 78.8 0.0 1.3 1 0 0 1 1 1 1 YEATS family WD40 PF00400.27 CBZ54835.1 - 3.9e-95 308.6 11.8 6.6e-14 51.1 0.0 8.5 8 0 0 8 8 8 8 WD domain, G-beta repeat NLE PF08154.7 CBZ54835.1 - 5.1e-09 36.0 0.4 8.1e-09 35.3 0.3 1.3 1 0 0 1 1 1 1 NLE (NUC135) domain Nup160 PF11715.3 CBZ54835.1 - 1.9e-07 29.6 8.4 0.033 12.3 0.2 4.8 1 1 2 5 5 5 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 CBZ54835.1 - 4.7e-05 22.3 0.1 0.057 12.1 0.0 2.9 2 1 0 2 2 2 2 Nup133 N terminal like eIF2A PF08662.6 CBZ54835.1 - 0.00064 19.4 0.0 0.84 9.3 0.0 3.4 3 1 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A PD40 PF07676.7 CBZ54835.1 - 0.00089 18.8 0.5 3.4 7.4 0.0 4.1 5 0 0 5 5 5 1 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.11 CBZ54835.1 - 0.0018 16.6 0.3 0.93 7.7 0.0 2.3 2 0 0 2 2 2 2 Cytochrome D1 heme domain DUF3312 PF11768.3 CBZ54835.1 - 0.048 11.8 0.0 1.6 6.8 0.0 2.8 3 1 1 4 4 4 0 Protein of unknown function (DUF3312) dCMP_cyt_deam_1 PF00383.17 CBZ54836.1 - 6.3e-07 28.9 0.6 1.9e-06 27.4 0.4 2.0 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region SAG PF04092.8 CBZ54837.1 - 6e-19 68.6 22.9 1.5e-09 38.2 5.0 2.3 2 0 0 2 2 2 2 SRS domain SAG PF04092.8 CBZ54838.1 - 1.9e-17 63.7 20.9 4.1e-09 36.8 5.2 2.3 2 0 0 2 2 2 2 SRS domain SAG PF04092.8 CBZ54839.1 - 2.2e-21 76.4 22.3 1.1e-10 41.9 3.2 2.1 2 0 0 2 2 2 2 SRS domain SAG PF04092.8 CBZ54840.1 - 8.1e-21 74.6 20.8 1.9e-10 41.2 6.9 2.1 2 0 0 2 2 2 2 SRS domain SAG PF04092.8 CBZ54841.1 - 2.1e-20 73.3 25.5 1.5e-10 41.4 6.4 2.3 2 0 0 2 2 2 2 SRS domain SAG PF04092.8 CBZ54842.1 - 8e-21 74.7 23.0 1.6e-10 41.4 5.2 2.1 2 0 0 2 2 2 2 SRS domain DND1_DSRM PF14709.1 CBZ54842.1 - 0.017 15.3 0.5 3.3 8.0 0.1 3.4 3 1 0 3 3 3 0 double strand RNA binding domain from DEAD END PROTEIN 1 SusE PF14292.1 CBZ54842.1 - 0.023 14.5 2.7 0.11 12.3 0.6 2.5 1 1 1 2 2 2 0 SusE outer membrane protein Cadherin-like PF12733.2 CBZ54842.1 - 0.05 13.8 0.2 0.05 13.8 0.2 2.4 3 1 0 3 3 3 0 Cadherin-like beta sandwich domain SAG PF04092.8 CBZ54843.1 - 8.9e-19 68.0 21.5 5.2e-10 39.7 4.8 2.1 2 0 0 2 2 2 2 SRS domain SAG PF04092.8 CBZ54844.1 - 1.4e-17 64.2 19.9 3.5e-09 37.1 8.4 2.3 2 0 0 2 2 2 2 SRS domain SAG PF04092.8 CBZ54845.1 - 5.8e-15 55.7 17.1 4.8e-10 39.8 3.4 2.2 2 0 0 2 2 2 2 SRS domain SAG PF04092.8 CBZ54846.1 - 1.3e-23 83.7 22.5 1.2e-13 51.5 4.9 2.2 2 0 0 2 2 2 2 SRS domain SAG PF04092.8 CBZ54847.1 - 2.4e-17 63.4 17.6 1.2e-09 38.5 2.5 2.2 2 0 0 2 2 2 2 SRS domain Endonuclease_7 PF02945.10 CBZ54847.1 - 0.082 12.6 0.2 0.26 10.9 0.1 1.9 2 0 0 2 2 2 0 Recombination endonuclease VII SAG PF04092.8 CBZ54848.1 - 1.9e-19 70.2 15.4 6.3e-10 39.5 2.0 2.1 2 0 0 2 2 2 2 SRS domain SAG PF04092.8 CBZ54849.1 - 1.5e-18 67.3 26.1 5.8e-11 42.8 6.1 2.6 2 1 1 3 3 3 2 SRS domain DUF3822 PF12864.2 CBZ54849.1 - 0.12 11.6 0.3 0.21 10.7 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3822) SAG PF04092.8 CBZ54850.1 - 3.5e-20 72.6 17.4 4.3e-11 43.2 3.3 2.3 2 0 0 2 2 2 2 SRS domain SAG PF04092.8 CBZ54851.1 - 5.6e-19 68.7 18.5 3.3e-10 40.4 5.2 2.2 2 0 0 2 2 2 2 SRS domain zf-C2H2_jaz PF12171.3 CBZ54852.1 - 0.00044 20.3 0.2 0.00073 19.6 0.1 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 CBZ54852.1 - 0.00084 19.4 0.2 0.0015 18.6 0.2 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-U1 PF06220.7 CBZ54852.1 - 0.019 14.5 0.2 0.033 13.7 0.1 1.3 1 0 0 1 1 1 0 U1 zinc finger Vfa1 PF08432.5 CBZ54852.1 - 1.5 8.7 9.5 3.8 7.4 6.6 1.6 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Penicil_amidase PF01804.13 CBZ54853.1 - 2.3e-75 255.0 0.0 4.4e-70 237.6 0.0 3.7 2 1 0 2 2 2 2 Penicillin amidase RabGAP-TBC PF00566.13 CBZ54854.1 - 1.2e-32 113.1 0.4 7.4e-18 64.8 0.0 2.3 2 0 0 2 2 2 2 Rab-GTPase-TBC domain SAG PF04092.8 CBZ54855.1 - 6.9e-18 65.2 12.5 2.2e-09 37.7 3.2 2.2 2 0 0 2 2 2 2 SRS domain SAG PF04092.8 CBZ54856.1 - 3.1e-22 79.2 17.0 6.1e-11 42.7 5.3 2.1 2 0 0 2 2 2 2 SRS domain SAG PF04092.8 CBZ54857.1 - 9.2e-15 55.1 5.2 6.4e-09 36.2 0.1 2.4 2 0 0 2 2 2 2 SRS domain SAG PF04092.8 CBZ54858.1 - 1.9e-14 54.1 12.8 2.2e-08 34.5 0.3 2.4 2 1 0 2 2 2 2 SRS domain SAG PF04092.8 CBZ54859.1 - 2.9e-14 53.5 7.2 3e-08 34.0 0.4 2.2 2 0 0 2 2 2 2 SRS domain PC_rep PF01851.17 CBZ54860.1 - 0.017 15.3 18.5 0.21 11.9 1.0 4.5 4 0 0 4 4 4 0 Proteasome/cyclosome repeat Amino_oxidase PF01593.19 CBZ54861.1 - 3.8e-71 240.4 0.9 9.2e-30 104.0 0.0 5.2 5 0 0 5 5 5 4 Flavin containing amine oxidoreductase zf-HC5HC2H PF13771.1 CBZ54861.1 - 2.6e-10 40.2 1.8 6.6e-10 39.0 1.2 1.7 1 0 0 1 1 1 1 PHD-like zinc-binding domain NAD_binding_8 PF13450.1 CBZ54861.1 - 5.7e-10 39.0 0.3 4.1e-09 36.3 0.2 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 CBZ54861.1 - 1.6e-06 28.1 0.3 3e-06 27.2 0.2 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 CBZ54861.1 - 5.5e-05 22.3 0.4 0.0001 21.5 0.3 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 CBZ54861.1 - 0.00011 22.3 0.1 0.00023 21.2 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 CBZ54861.1 - 0.00036 19.5 1.7 0.00053 18.9 1.2 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A zf-HC5HC2H_2 PF13832.1 CBZ54861.1 - 0.0025 17.7 3.0 0.0062 16.5 2.1 1.6 1 0 0 1 1 1 1 PHD-zinc-finger like domain Thi4 PF01946.12 CBZ54861.1 - 0.033 13.2 0.1 0.055 12.5 0.0 1.2 1 0 0 1 1 1 0 Thi4 family Pyr_redox PF00070.22 CBZ54861.1 - 0.041 14.2 0.7 0.11 12.9 0.5 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase IlvN PF07991.7 CBZ54861.1 - 0.055 12.8 0.1 0.11 11.8 0.1 1.4 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain CPSase_L_chain PF00289.17 CBZ54861.1 - 0.061 13.4 0.3 0.12 12.4 0.2 1.5 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, N-terminal domain Shikimate_DH PF01488.15 CBZ54861.1 - 0.085 12.9 0.1 0.18 11.8 0.1 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase HI0933_like PF03486.9 CBZ54861.1 - 0.086 11.2 0.8 0.13 10.6 0.6 1.2 1 0 0 1 1 1 0 HI0933-like protein DUF1394 PF07159.7 CBZ54861.1 - 3.1 6.8 0.0 4.8 6.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1394) DUF342 PF03961.8 CBZ54862.1 - 0.59 8.4 4.3 1.1 7.5 3.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF342) GRA6 PF05084.8 CBZ54863.1 - 9.5e-96 319.4 10.7 1.1e-95 319.1 7.4 1.1 1 0 0 1 1 1 1 Granule antigen protein (GRA6) CENP-T PF15511.1 CBZ54863.1 - 0.012 14.8 4.7 0.015 14.5 3.3 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T AJAP1_PANP_C PF15298.1 CBZ54863.1 - 0.027 14.3 0.1 0.067 13.0 0.1 1.6 1 1 0 1 1 1 0 AJAP1/PANP C-terminus Myb_Cef PF11831.3 CBZ54866.1 - 3.6e-33 114.7 6.8 3.6e-33 114.7 4.7 4.2 3 1 0 3 3 3 1 pre-mRNA splicing factor component Myb_DNA-binding PF00249.26 CBZ54866.1 - 7.7e-20 70.6 5.6 2e-10 40.5 0.2 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 CBZ54866.1 - 1.1e-16 60.6 2.7 5.1e-12 45.7 1.4 3.2 1 1 1 2 2 2 2 Myb-like DNA-binding domain Nup84_Nup100 PF04121.8 CBZ54867.1 - 5.9e-07 27.5 0.0 0.0012 16.6 0.0 2.3 2 0 0 2 2 2 2 Nuclear pore protein 84 / 107 VGCC_alpha2 PF08473.6 CBZ54867.1 - 0.088 12.5 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 Neuronal voltage-dependent calcium channel alpha 2acd SAG PF04092.8 CBZ54868.1 - 2.1e-13 50.7 13.9 4.3e-08 33.5 5.1 2.3 2 0 0 2 2 2 2 SRS domain SAG PF04092.8 CBZ54869.1 - 2.3e-14 53.8 15.4 6.1e-07 29.8 5.2 2.3 2 0 0 2 2 2 2 SRS domain SAG PF04092.8 CBZ54870.1 - 3.4e-16 59.7 17.4 2.6e-08 34.3 5.4 2.2 2 0 0 2 2 2 2 SRS domain DUF445 PF04286.7 CBZ54871.1 - 0.093 12.2 3.3 0.086 12.3 0.4 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF445) DUF1510 PF07423.6 CBZ54872.1 - 0.0018 17.6 7.6 0.0018 17.6 5.2 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1510) TT_ORF1 PF02956.9 CBZ54872.1 - 0.0078 14.7 0.2 0.011 14.2 0.1 1.2 1 0 0 1 1 1 1 TT viral orf 1 FAM176 PF14851.1 CBZ54872.1 - 0.017 14.7 2.5 0.066 12.8 1.7 1.9 2 0 0 2 2 2 0 FAM176 family Daxx PF03344.10 CBZ54872.1 - 0.033 12.6 14.8 0.049 12.1 10.2 1.2 1 0 0 1 1 1 0 Daxx Family CobT PF06213.7 CBZ54872.1 - 0.036 13.1 14.9 0.072 12.2 10.3 1.4 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF1183 PF06682.7 CBZ54872.1 - 0.11 12.0 0.1 0.18 11.3 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) SAPS PF04499.10 CBZ54872.1 - 0.12 10.9 0.5 0.14 10.7 0.4 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Zip PF02535.17 CBZ54872.1 - 0.14 11.1 2.1 0.22 10.4 1.4 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Ycf1 PF05758.7 CBZ54872.1 - 0.23 9.1 0.3 0.25 9.0 0.2 1.1 1 0 0 1 1 1 0 Ycf1 SpoIIIAH PF12685.2 CBZ54872.1 - 0.26 10.7 10.9 0.024 14.1 3.3 2.1 2 0 0 2 2 2 0 SpoIIIAH-like protein Nucleoplasmin PF03066.10 CBZ54872.1 - 1 8.8 10.4 2.3 7.7 7.2 1.5 1 0 0 1 1 1 0 Nucleoplasmin Ribonuc_red_sm PF00268.16 CBZ54873.1 - 5.3e-109 363.5 2.1 6.5e-109 363.2 1.5 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain Alg14 PF08660.6 CBZ54874.1 - 1.6e-43 148.6 0.0 3.6e-43 147.5 0.0 1.6 1 1 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like DUF3692 PF12469.3 CBZ54874.1 - 0.12 12.5 0.0 0.17 12.1 0.0 1.4 1 0 0 1 1 1 0 CRISPR-associated protein MOZ_SAS PF01853.13 CBZ54875.1 - 1.2e-76 256.1 0.0 1.7e-76 255.6 0.0 1.2 1 0 0 1 1 1 1 MOZ/SAS family Tudor-knot PF11717.3 CBZ54875.1 - 1.2e-08 34.5 0.6 6.6e-08 32.1 0.7 2.1 2 0 0 2 2 2 1 RNA binding activity-knot of a chromodomain zf-ribbon_3 PF13248.1 CBZ54875.1 - 0.034 13.3 3.8 0.084 12.1 2.7 1.7 1 0 0 1 1 1 0 zinc-ribbon domain UPF0547 PF10571.4 CBZ54875.1 - 5.4 6.7 5.5 3.2 7.5 1.8 2.0 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 Methyltransf_18 PF12847.2 CBZ54876.1 - 0.053 14.1 0.0 0.11 13.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain PRMT5 PF05185.11 CBZ54876.1 - 0.21 10.4 0.0 0.39 9.5 0.0 1.3 1 0 0 1 1 1 0 PRMT5 arginine-N-methyltransferase Sad1_UNC PF07738.8 CBZ54877.1 - 1.9e-19 69.7 0.1 3.8e-19 68.8 0.1 1.5 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal Ion_trans PF00520.26 CBZ54877.1 - 4.4 6.4 0.6 1.7e+02 1.3 1.2 2.1 2 0 0 2 2 2 0 Ion transport protein SAG PF04092.8 CBZ54878.1 - 8.6e-22 77.8 6.5 3.6e-15 56.4 1.9 2.1 2 0 0 2 2 2 2 SRS domain IGPS PF00218.16 CBZ54880.1 - 1e-23 83.7 0.0 2e-23 82.7 0.0 1.4 1 0 0 1 1 1 1 Indole-3-glycerol phosphate synthase NanE PF04131.9 CBZ54880.1 - 0.00013 21.0 0.0 0.00013 21.0 0.0 1.8 2 0 0 2 2 2 1 Putative N-acetylmannosamine-6-phosphate epimerase His_biosynth PF00977.16 CBZ54880.1 - 0.1 11.8 0.1 0.23 10.6 0.0 1.5 1 0 0 1 1 1 0 Histidine biosynthesis protein PcrB PF01884.12 CBZ54880.1 - 0.11 11.7 0.0 0.28 10.3 0.0 1.5 2 0 0 2 2 2 0 PcrB family ubiquitin PF00240.18 CBZ54885.1 - 6.7e-05 22.2 0.0 0.0001 21.6 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 CBZ54885.1 - 0.069 12.8 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 CBZ54885.1 - 0.11 12.7 0.0 0.13 12.4 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin-like domain DHQ_synthase PF01761.15 CBZ54886.1 - 3e-70 236.1 0.2 3.9e-42 143.9 0.1 2.6 3 0 0 3 3 3 2 3-dehydroquinate synthase EPSP_synthase PF00275.15 CBZ54886.1 - 1.3e-24 86.4 7.8 9e-07 27.6 0.1 7.8 6 2 0 6 6 6 5 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DHquinase_I PF01487.10 CBZ54886.1 - 6.2e-14 52.1 0.1 2.2e-07 30.7 0.0 3.6 3 0 0 3 3 3 3 Type I 3-dehydroquinase SKI PF01202.17 CBZ54886.1 - 1.6e-12 47.6 0.2 1.9e-05 24.5 0.0 4.3 5 0 0 5 5 5 2 Shikimate kinase Shikimate_DH PF01488.15 CBZ54886.1 - 5.4e-05 23.3 0.2 0.048 13.7 0.0 2.8 3 0 0 3 3 3 2 Shikimate / quinate 5-dehydrogenase Fe-ADH_2 PF13685.1 CBZ54886.1 - 0.0011 18.3 1.4 0.018 14.3 0.3 2.5 3 0 0 3 3 3 1 Iron-containing alcohol dehydrogenase AAA_17 PF13207.1 CBZ54886.1 - 0.052 14.3 0.0 0.14 13.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 CBZ54886.1 - 1.3 8.8 0.0 2.6 7.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.17 CBZ54886.1 - 2.3 7.0 0.0 3.9 6.2 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain PNP_UDP_1 PF01048.15 CBZ54887.1 - 7e-34 116.8 0.2 8.1e-34 116.6 0.1 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily Drf_FH1 PF06346.7 CBZ54888.1 - 0.098 12.1 11.0 0.14 11.6 7.6 1.2 1 0 0 1 1 1 0 Formin Homology Region 1 JmjC PF02373.17 CBZ54889.1 - 1.6e-35 121.7 0.3 2.8e-35 120.9 0.2 1.4 1 0 0 1 1 1 1 JmjC domain, hydroxylase JmjN PF02375.12 CBZ54889.1 - 0.0037 16.7 0.0 0.0074 15.7 0.0 1.5 1 0 0 1 1 1 1 jmjN domain DUF4570 PF15134.1 CBZ54889.1 - 0.014 15.1 0.0 0.11 12.3 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4570) Thymidylate_kin PF02223.12 CBZ54892.1 - 4.8e-30 104.3 0.0 8.2e-23 80.7 0.0 2.1 1 1 1 2 2 2 2 Thymidylate kinase AAA_28 PF13521.1 CBZ54892.1 - 0.014 15.3 0.1 0.057 13.3 0.1 2.0 1 1 0 1 1 1 0 AAA domain B3_4 PF03483.12 CBZ54893.1 - 7.5e-23 80.8 0.0 1.5e-22 79.8 0.0 1.5 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.10 CBZ54893.1 - 2.1e-16 59.5 0.0 2.9e-13 49.4 0.0 2.6 2 0 0 2 2 2 2 tRNA synthetase B5 domain DUF3708 PF12501.3 CBZ54894.1 - 0.045 13.6 4.9 0.99 9.2 1.2 2.4 2 0 0 2 2 2 0 Phosphate ATP-binding cassette transporter AAA_13 PF13166.1 CBZ54894.1 - 0.44 8.9 3.4 0.69 8.3 2.4 1.2 1 0 0 1 1 1 0 AAA domain DUF4200 PF13863.1 CBZ54894.1 - 1.2 9.0 19.5 0.09 12.7 8.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) V_ATPase_I PF01496.14 CBZ54894.1 - 2.7 5.7 3.6 3.8 5.2 2.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF1664 PF07889.7 CBZ54894.1 - 8.9 6.1 7.1 21 4.9 2.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) RAP PF08373.5 CBZ54895.1 - 1.2e-16 60.2 0.0 1.9e-16 59.5 0.0 1.4 1 0 0 1 1 1 1 RAP domain RNA_pol_Rpb1_4 PF05000.12 CBZ54895.1 - 0.2 11.3 0.0 0.43 10.3 0.0 1.5 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 4 Proteasome PF00227.21 CBZ54896.1 - 1.9e-44 151.2 0.4 2.3e-44 150.9 0.2 1.1 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.3 CBZ54896.1 - 0.002 17.3 0.0 0.0045 16.2 0.0 1.6 1 0 0 1 1 1 1 Proteasome beta subunits C terminal Proteasom_PSMB PF10508.4 CBZ54898.1 - 1.2e-34 119.4 0.0 3.7e-34 117.8 0.0 1.6 1 1 0 1 1 1 1 Proteasome non-ATPase 26S subunit HEAT_2 PF13646.1 CBZ54898.1 - 0.023 14.9 1.2 0.023 14.9 0.8 3.7 3 1 2 5 5 5 0 HEAT repeats Nol1_Nop2_Fmu PF01189.12 CBZ54899.1 - 6.5e-31 107.7 0.0 1.1e-30 106.9 0.0 1.4 1 0 0 1 1 1 1 NOL1/NOP2/sun family Methyltransf_26 PF13659.1 CBZ54899.1 - 3.9e-08 33.3 0.1 2.5e-07 30.7 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain PUA PF01472.15 CBZ54899.1 - 7.3e-07 28.8 0.0 2.3e-06 27.2 0.0 1.8 1 0 0 1 1 1 1 PUA domain Methyltransf_18 PF12847.2 CBZ54899.1 - 7.6e-06 26.4 0.0 1.7e-05 25.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CBZ54899.1 - 0.00019 21.0 0.0 0.095 12.2 0.0 2.5 3 0 0 3 3 3 2 Methyltransferase domain FtsJ PF01728.14 CBZ54899.1 - 0.00057 19.9 0.0 0.001 19.0 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase PCMT PF01135.14 CBZ54899.1 - 0.0018 17.8 0.0 0.0044 16.5 0.0 1.6 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PRY PF13765.1 CBZ54899.1 - 0.051 13.1 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 SPRY-associated domain Fibrillarin PF01269.12 CBZ54899.1 - 0.22 10.3 0.0 0.38 9.6 0.0 1.2 1 0 0 1 1 1 0 Fibrillarin Lon_C PF05362.8 CBZ54901.1 - 4.8e-68 228.5 0.2 4.1e-57 192.8 0.0 3.0 3 0 0 3 3 3 2 Lon protease (S16) C-terminal proteolytic domain AAA PF00004.24 CBZ54901.1 - 5.3e-21 75.2 0.0 1.3e-20 73.9 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) LON PF02190.11 CBZ54901.1 - 1.6e-17 63.9 2.3 3.2e-17 62.9 0.0 2.5 2 1 0 2 2 2 1 ATP-dependent protease La (LON) domain AAA_5 PF07728.9 CBZ54901.1 - 2.9e-08 33.5 0.0 2e-07 30.8 0.0 2.4 3 0 0 3 3 2 1 AAA domain (dynein-related subfamily) ChlI PF13541.1 CBZ54901.1 - 5e-08 32.4 0.0 9.6e-08 31.5 0.0 1.5 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_22 PF13401.1 CBZ54901.1 - 4.6e-06 26.8 0.5 4.8e-05 23.5 0.0 2.7 2 1 0 2 2 1 1 AAA domain AAA_2 PF07724.9 CBZ54901.1 - 1.6e-05 24.8 0.0 4.6e-05 23.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 CBZ54901.1 - 3.7e-05 23.8 0.3 0.00035 20.6 0.2 2.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_PrkA PF08298.6 CBZ54901.1 - 4.1e-05 22.4 0.0 8.1e-05 21.4 0.0 1.4 1 0 0 1 1 1 1 PrkA AAA domain AAA_18 PF13238.1 CBZ54901.1 - 7.4e-05 23.0 1.5 0.0059 16.9 0.0 3.0 3 0 0 3 3 2 1 AAA domain AAA_17 PF13207.1 CBZ54901.1 - 7.9e-05 23.4 0.0 0.00036 21.3 0.0 2.2 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 CBZ54901.1 - 0.0053 15.8 0.0 0.015 14.3 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus IstB_IS21 PF01695.12 CBZ54901.1 - 0.01 15.2 0.0 0.027 13.9 0.0 1.7 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_14 PF13173.1 CBZ54901.1 - 0.011 15.6 0.0 0.039 13.8 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.6 CBZ54901.1 - 0.023 14.3 0.0 0.048 13.2 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TIP49 PF06068.8 CBZ54901.1 - 0.025 13.3 0.5 0.09 11.4 0.0 1.9 2 0 0 2 2 2 0 TIP49 C-terminus ATP-synt_ab PF00006.20 CBZ54901.1 - 0.029 13.8 0.0 0.05 13.1 0.0 1.3 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_25 PF13481.1 CBZ54901.1 - 0.032 13.6 0.0 0.097 12.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain DUF258 PF03193.11 CBZ54901.1 - 0.033 13.3 0.0 0.064 12.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 MobB PF03205.9 CBZ54901.1 - 0.075 12.7 0.0 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B NTPase_1 PF03266.10 CBZ54901.1 - 0.087 12.5 0.1 0.26 10.9 0.0 1.8 1 1 1 2 2 2 0 NTPase RNA_helicase PF00910.17 CBZ54901.1 - 0.091 12.9 0.0 0.19 11.9 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_24 PF13479.1 CBZ54901.1 - 0.14 11.7 0.0 0.25 10.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain SOG2 PF10428.4 CBZ54901.1 - 3.4 6.2 12.6 4.5 5.8 7.7 1.9 2 0 0 2 2 2 0 RAM signalling pathway protein JAB PF01398.16 CBZ54902.1 - 7.7e-23 80.4 0.0 1.3e-22 79.6 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.1 CBZ54902.1 - 8.4e-06 25.3 0.0 4e-05 23.1 0.0 2.2 1 1 0 1 1 1 1 Prokaryotic homologs of the JAB domain Ank_2 PF12796.2 CBZ54903.1 - 7.1e-41 138.4 11.4 1.4e-14 54.1 1.8 5.0 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.25 CBZ54903.1 - 7.2e-34 113.9 9.9 1.8e-07 30.6 0.4 7.9 6 1 0 6 6 6 6 Ankyrin repeat Ank_5 PF13857.1 CBZ54903.1 - 1.2e-29 101.6 13.0 1.1e-10 41.4 0.4 5.8 3 2 3 6 6 6 6 Ankyrin repeats (many copies) Ank_4 PF13637.1 CBZ54903.1 - 5.9e-26 90.3 9.0 1.9e-10 40.9 0.4 6.2 3 1 3 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 CBZ54903.1 - 1.1e-23 80.8 7.1 0.00012 21.9 0.0 7.7 7 0 0 7 7 7 5 Ankyrin repeat Sushi PF00084.15 CBZ54903.1 - 1.3e-05 25.4 0.2 2.8e-05 24.3 0.1 1.6 1 0 0 1 1 1 1 Sushi domain (SCR repeat) DSPc PF00782.15 CBZ54904.1 - 1.1e-30 105.9 0.0 1.3e-30 105.6 0.0 1.0 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.1 CBZ54904.1 - 0.00021 21.3 0.0 0.00027 21.0 0.0 1.1 1 0 0 1 1 1 1 Inositol hexakisphosphate Init_tRNA_PT PF04179.7 CBZ54904.1 - 0.0015 17.4 0.0 0.0018 17.2 0.0 1.1 1 0 0 1 1 1 1 Initiator tRNA phosphoribosyl transferase Y_phosphatase PF00102.22 CBZ54904.1 - 0.0025 17.2 0.2 0.0044 16.3 0.1 1.5 1 1 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.1 CBZ54904.1 - 0.15 12.2 0.0 1.1 9.5 0.0 1.8 1 1 1 2 2 2 0 Tyrosine phosphatase family SAG PF04092.8 CBZ54905.1 - 3.2e-33 114.7 11.3 6.5e-26 91.1 7.6 2.1 2 0 0 2 2 2 2 SRS domain DUF3403 PF11883.3 CBZ54905.1 - 0.92 9.8 4.0 24 5.2 0.1 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF3403) zf-CCCH_2 PF14608.1 CBZ54908.1 - 2.2e-07 30.5 21.1 0.00026 20.8 3.6 3.1 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type PWI PF01480.12 CBZ54908.1 - 0.024 14.7 0.1 0.04 14.0 0.0 1.3 1 0 0 1 1 1 0 PWI domain MIP-T3 PF10243.4 CBZ54908.1 - 1.2 7.5 12.2 1.7 6.9 8.4 1.3 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 zf-CCCH PF00642.19 CBZ54908.1 - 3.4 7.4 10.0 0.3 10.8 0.4 2.9 3 0 0 3 3 3 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) IMS PF00817.15 CBZ54909.1 - 1.2e-05 25.1 0.0 8.3e-05 22.4 0.0 2.1 2 0 0 2 2 2 1 impB/mucB/samB family IMS_HHH PF11798.3 CBZ54909.1 - 5.4e-05 22.9 0.0 0.00012 21.9 0.0 1.6 1 0 0 1 1 1 1 IMS family HHH motif DUF1409 PF07197.7 CBZ54909.1 - 0.024 14.6 1.5 0.48 10.5 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1409) HHH_7 PF14635.1 CBZ54910.1 - 9.8e-14 51.3 0.0 9.1e-12 45.0 0.0 2.5 2 0 0 2 2 2 1 Helix-hairpin-helix motif HTH_44 PF14641.1 CBZ54910.1 - 1.5e-05 25.0 0.1 4.8e-05 23.3 0.1 1.9 1 0 0 1 1 1 1 Helix-turn-helix DNA-binding domain of SPT6 Cwf_Cwc_15 PF04889.7 CBZ54910.1 - 0.00025 20.8 8.8 0.00025 20.8 6.1 8.0 7 2 0 7 7 7 1 Cwf15/Cwc15 cell cycle control protein SH2_2 PF14633.1 CBZ54910.1 - 0.0075 15.3 0.0 2.6 7.0 0.0 2.6 2 0 0 2 2 2 2 SH2 domain Parvo_NS1 PF01057.12 CBZ54910.1 - 5.3 5.8 2.2 9.1 5.0 1.5 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 RRM_6 PF14259.1 CBZ54911.1 - 5.4e-20 71.1 0.0 1e-09 38.1 0.0 4.1 4 0 0 4 4 4 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CBZ54911.1 - 8.3e-14 50.9 0.0 6.1e-06 25.7 0.0 4.6 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBZ54911.1 - 7.8e-09 35.2 0.1 0.027 14.3 0.0 3.5 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ribosomal_L33 PF00471.15 CBZ54912.1 - 1.3e-10 41.3 0.8 5.2e-10 39.4 0.1 2.0 2 0 0 2 2 2 1 Ribosomal protein L33 UPF0561 PF10573.4 CBZ54913.1 - 2.7 7.8 10.0 1 9.2 2.1 3.0 2 0 0 2 2 2 0 Uncharacterised protein family UPF0561 His_Phos_2 PF00328.17 CBZ54914.1 - 0.00083 18.7 0.0 0.39 9.9 0.0 2.8 3 0 0 3 3 3 2 Histidine phosphatase superfamily (branch 2) AAA PF00004.24 CBZ54915.1 - 2.9e-43 147.2 0.0 3.8e-41 140.3 0.0 2.8 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 CBZ54915.1 - 8.2e-08 32.4 2.1 0.02 14.9 0.3 3.5 2 1 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.1 CBZ54915.1 - 9.2e-06 25.8 0.4 0.092 12.8 0.0 3.5 2 1 1 3 3 3 2 AAA domain AAA_17 PF13207.1 CBZ54915.1 - 3.8e-05 24.4 0.0 0.26 12.1 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.9 CBZ54915.1 - 0.00012 21.8 1.5 0.014 15.1 0.2 3.6 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 CBZ54915.1 - 0.00025 20.7 0.6 0.011 15.4 0.0 3.0 3 0 0 3 3 3 1 Part of AAA domain ABC_tran PF00005.22 CBZ54915.1 - 0.00027 21.2 0.6 0.23 11.7 0.0 3.3 3 1 0 3 3 2 1 ABC transporter AAA_33 PF13671.1 CBZ54915.1 - 0.00062 19.6 3.9 0.077 12.8 0.0 3.6 3 0 0 3 3 3 1 AAA domain AAA_14 PF13173.1 CBZ54915.1 - 0.00073 19.4 0.0 0.0046 16.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_2 PF07724.9 CBZ54915.1 - 0.0016 18.3 0.0 0.0043 16.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.12 CBZ54915.1 - 0.0036 16.7 0.1 0.13 11.7 0.0 2.4 2 0 0 2 2 2 1 IstB-like ATP binding protein RNA_helicase PF00910.17 CBZ54915.1 - 0.014 15.5 0.0 1.6 8.9 0.0 2.5 2 0 0 2 2 2 0 RNA helicase Mg_chelatase PF01078.16 CBZ54915.1 - 0.026 13.6 0.1 0.026 13.6 0.0 2.7 4 0 0 4 4 4 0 Magnesium chelatase, subunit ChlI RuvB_N PF05496.7 CBZ54915.1 - 0.027 13.5 0.0 0.05 12.6 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_18 PF13238.1 CBZ54915.1 - 0.04 14.2 0.2 0.96 9.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 CBZ54915.1 - 0.046 13.3 1.5 2.2 7.9 0.1 3.4 2 2 0 2 2 2 0 NACHT domain Sigma54_activ_2 PF14532.1 CBZ54915.1 - 0.047 13.7 0.0 0.22 11.5 0.0 2.1 2 0 0 2 2 2 0 Sigma-54 interaction domain TIP49 PF06068.8 CBZ54915.1 - 0.18 10.4 0.1 0.3 9.7 0.0 1.3 1 0 0 1 1 1 0 TIP49 C-terminus AAA_29 PF13555.1 CBZ54915.1 - 0.2 11.2 0.5 27 4.3 0.2 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain DUF2217 PF10265.4 CBZ54919.1 - 4.2 6.0 5.7 7.7 5.1 3.9 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) EFP PF01132.15 CBZ54920.1 - 5.6e-05 22.7 0.0 8.6e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 Elongation factor P (EF-P) OB domain EFP_N PF08207.7 CBZ54920.1 - 0.00059 19.6 0.1 0.0011 18.8 0.0 1.5 1 0 0 1 1 1 1 Elongation factor P (EF-P) KOW-like domain ATP_bind_3 PF01171.15 CBZ54921.1 - 2.4e-17 63.0 0.0 3.3e-09 36.5 0.0 2.2 2 0 0 2 2 2 2 PP-loop family tRNA_Me_trans PF03054.11 CBZ54921.1 - 0.0003 19.4 0.0 0.00093 17.8 0.0 1.7 2 0 0 2 2 2 1 tRNA methyl transferase PAPS_reduct PF01507.14 CBZ54921.1 - 0.0019 18.0 0.0 0.42 10.4 0.0 2.5 2 0 0 2 2 2 2 Phosphoadenosine phosphosulfate reductase family RecR PF02132.10 CBZ54921.1 - 0.016 14.5 0.3 0.016 14.5 0.2 3.3 4 0 0 4 4 4 0 RecR protein Asn_synthase PF00733.16 CBZ54921.1 - 0.069 12.6 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Asparagine synthase SLBP_RNA_bind PF15247.1 CBZ54923.1 - 8.9e-22 76.6 0.7 2e-21 75.4 0.5 1.5 1 0 0 1 1 1 1 Histone RNA hairpin-binding protein RNA-binding domain Adaptin_binding PF10199.4 CBZ54924.1 - 7.9e-13 48.8 0.5 2.1e-12 47.4 0.3 1.7 1 1 0 1 1 1 1 Alpha and gamma adaptin binding protein p34 UCH PF00443.24 CBZ54925.1 - 2.1e-26 92.6 0.0 9.2e-16 57.7 0.0 2.9 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CBZ54925.1 - 2.6e-13 50.1 2.8 6.9e-11 42.1 0.0 3.2 3 0 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase Baculo_PEP_C PF04513.7 CBZ54928.1 - 0.49 10.2 2.2 1 9.1 1.5 1.6 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus APG6 PF04111.7 CBZ54928.1 - 1.8 7.5 18.4 0.056 12.4 8.0 1.9 2 0 0 2 2 2 0 Autophagy protein Apg6 Peroxin-3 PF04882.7 CBZ54929.1 - 8.1e-10 37.9 0.0 3.2e-09 36.0 0.0 2.0 2 0 0 2 2 2 1 Peroxin-3 DUF2890 PF11081.3 CBZ54929.1 - 0.0025 17.9 0.6 0.0025 17.9 0.4 5.6 5 2 1 6 6 6 1 Protein of unknown function (DUF2890) tRNA_Me_trans PF03054.11 CBZ54930.1 - 8.7e-75 251.4 0.0 2.7e-37 128.1 0.0 3.9 4 0 0 4 4 4 3 tRNA methyl transferase SufE PF02657.10 CBZ54930.1 - 0.00056 19.5 0.0 0.0017 17.9 0.0 1.7 2 0 0 2 2 2 1 Fe-S metabolism associated domain Asn_synthase PF00733.16 CBZ54930.1 - 0.003 17.0 0.0 0.0056 16.1 0.0 1.3 1 0 0 1 1 1 1 Asparagine synthase ThiI PF02568.9 CBZ54930.1 - 0.028 13.8 0.0 0.046 13.1 0.0 1.3 1 0 0 1 1 1 0 Thiamine biosynthesis protein (ThiI) Ribosomal_L4 PF00573.17 CBZ54931.1 - 2e-41 141.5 0.1 4.4e-41 140.3 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.1 CBZ54931.1 - 1e-23 83.0 3.3 1e-23 83.0 2.3 2.1 1 1 0 1 1 1 1 60S ribosomal protein L4 C-terminal domain WD40 PF00400.27 CBZ54932.1 - 2e-18 65.4 11.7 0.00013 21.6 0.4 6.6 6 0 0 6 6 6 6 WD domain, G-beta repeat LisH PF08513.6 CBZ54932.1 - 2.1e-07 30.4 0.3 4.2e-07 29.4 0.2 1.5 1 0 0 1 1 1 1 LisH Nup160 PF11715.3 CBZ54932.1 - 0.078 11.0 0.0 2.6 6.0 0.0 2.2 2 0 0 2 2 2 0 Nucleoporin Nup120/160 IKI3 PF04762.7 CBZ54932.1 - 0.17 9.6 0.0 0.35 8.6 0.0 1.4 1 0 0 1 1 1 0 IKI3 family HBS1_N PF08938.5 CBZ54933.1 - 1.1e-05 25.4 39.3 27 4.9 0.1 11.2 11 0 0 11 11 11 11 HBS1 N-terminus TAFII55_N PF04658.8 CBZ54934.1 - 3.8e-15 55.7 5.5 9.3e-10 38.2 0.0 3.3 4 0 0 4 4 4 2 TAFII55 protein conserved region DUF1168 PF06658.7 CBZ54934.1 - 0.14 11.6 14.4 0.28 10.7 10.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) TRAPPC9-Trs120 PF08626.6 CBZ54935.1 - 0.27 8.4 0.0 0.38 8.0 0.0 1.1 1 0 0 1 1 1 0 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit zf-CCCH PF00642.19 CBZ54936.1 - 0.0012 18.4 11.8 0.012 15.3 1.4 3.0 2 1 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) AhpC-TSA PF00578.16 CBZ54937.1 - 7.1e-29 100.0 0.0 1e-28 99.5 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family 1-cysPrx_C PF10417.4 CBZ54937.1 - 3.1e-15 55.5 0.3 7.2e-15 54.3 0.2 1.7 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Redoxin PF08534.5 CBZ54937.1 - 5.6e-11 42.1 0.0 7.4e-11 41.7 0.0 1.2 1 0 0 1 1 1 1 Redoxin AhpC-TSA_2 PF13911.1 CBZ54937.1 - 0.001 18.9 0.0 0.0018 18.1 0.0 1.5 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme ArfGap PF01412.13 CBZ54938.1 - 8.8e-43 144.8 0.3 1.8e-42 143.8 0.2 1.5 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf CorA PF01544.13 CBZ54939.1 - 0.00065 18.8 0.0 0.0018 17.4 0.0 1.6 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF998 PF06197.8 CBZ54939.1 - 0.12 11.6 2.2 0.23 10.7 1.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF998) adh_short PF00106.20 CBZ54941.1 - 1.6e-12 47.6 0.1 6.5e-12 45.6 0.1 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CBZ54941.1 - 0.014 15.1 0.0 0.025 14.3 0.0 1.3 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CBZ54941.1 - 0.042 13.5 0.1 0.09 12.4 0.1 1.5 1 0 0 1 1 1 0 KR domain zf-RING_UBOX PF13445.1 CBZ54942.1 - 6.2e-07 29.0 5.0 6.2e-07 29.0 3.5 2.0 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.20 CBZ54942.1 - 7.7e-07 28.6 6.0 7.7e-07 28.6 4.1 3.1 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CBZ54942.1 - 6.9e-06 25.9 5.8 6.9e-06 25.9 4.0 3.4 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-B_box PF00643.19 CBZ54942.1 - 7.6e-06 25.7 1.3 7.6e-06 25.7 0.9 3.4 5 0 0 5 5 5 1 B-box zinc finger zf-C3HC4_4 PF15227.1 CBZ54942.1 - 7e-05 22.6 5.5 7e-05 22.6 3.8 3.1 3 0 0 3 3 3 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 CBZ54942.1 - 0.00027 20.5 5.9 0.00027 20.5 4.1 3.5 3 0 0 3 3 3 1 zinc-RING finger domain zf-RING_2 PF13639.1 CBZ54942.1 - 0.0011 18.7 16.1 0.0011 18.7 11.2 3.3 3 1 0 3 3 3 1 Ring finger domain FYVE PF01363.16 CBZ54942.1 - 0.19 11.6 13.8 0.15 11.9 1.1 3.0 3 0 0 3 3 3 0 FYVE zinc finger HD_3 PF13023.1 CBZ54943.1 - 1.8e-42 144.8 0.1 9.8e-42 142.4 0.1 1.9 1 1 0 1 1 1 1 HD domain HD PF01966.17 CBZ54943.1 - 0.00015 21.7 0.0 0.0007 19.6 0.0 2.1 2 1 0 2 2 2 1 HD domain HD_2 PF12917.2 CBZ54943.1 - 0.021 14.6 0.0 0.032 14.0 0.0 1.2 1 0 0 1 1 1 0 HD containing hydrolase-like enzyme SAG PF04092.8 CBZ54944.1 - 1.9e-10 41.1 3.3 2.8e-10 40.6 2.3 1.2 1 0 0 1 1 1 1 SRS domain Adaptin_N PF01602.15 CBZ54945.1 - 1.2e-41 142.6 0.0 5.6e-33 114.0 0.0 3.4 3 1 0 3 3 3 3 Adaptin N terminal region RRM_1 PF00076.17 CBZ54945.1 - 0.091 12.4 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nuf2 PF03800.9 CBZ54946.1 - 8.9e-15 54.9 0.1 4e-14 52.8 0.0 2.1 2 0 0 2 2 2 1 Nuf2 family Pox_G5 PF04599.7 CBZ54946.1 - 0.32 9.6 3.7 0.6 8.7 2.5 1.4 1 0 0 1 1 1 0 Poxvirus G5 protein SMC_N PF02463.14 CBZ54948.1 - 5.9e-14 51.8 18.6 4.5e-07 29.3 0.0 2.3 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 CBZ54948.1 - 1.4e-08 35.2 9.3 1.4e-08 35.2 6.5 5.7 2 2 1 3 3 3 1 AAA domain AAA_21 PF13304.1 CBZ54948.1 - 0.00029 20.9 0.0 0.0016 18.4 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 CBZ54948.1 - 0.032 13.7 0.1 0.071 12.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain C2 PF00168.25 CBZ54950.1 - 3.4e-29 100.5 0.0 1.6e-08 34.2 0.0 6.7 6 0 0 6 6 6 6 C2 domain FerI PF08151.7 CBZ54950.1 - 0.00029 20.7 0.0 0.0048 16.8 0.0 2.6 3 0 0 3 3 3 1 FerI (NUC094) domain GvpG PF05120.7 CBZ54951.1 - 0.038 13.7 0.0 0.099 12.4 0.0 1.7 1 0 0 1 1 1 0 Gas vesicle protein G DUF3810 PF12725.2 CBZ54953.1 - 0.081 11.8 0.1 0.11 11.3 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) Bax1-I PF01027.15 CBZ54954.1 - 1.3e-36 126.1 25.6 1.5e-36 125.9 17.7 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 DUF3185 PF11381.3 CBZ54954.1 - 0.14 11.9 4.1 1 9.1 0.3 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3185) DUF2530 PF10745.4 CBZ54954.1 - 5.4 7.0 7.3 1.8 8.5 0.7 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF2530) PIRT PF15099.1 CBZ54954.1 - 7.5 5.7 9.4 7.7 5.7 2.3 2.4 2 0 0 2 2 2 0 Phosphoinositide-interacting protein family DEAD PF00270.24 CBZ54955.1 - 1.2e-37 129.0 0.0 1.9e-37 128.3 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CBZ54955.1 - 2.7e-24 84.8 0.3 6.7e-24 83.5 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain GUCT PF08152.7 CBZ54955.1 - 4.1e-09 36.2 0.0 4.2e-08 33.0 0.0 2.2 1 1 0 1 1 1 1 GUCT (NUC152) domain ResIII PF04851.10 CBZ54955.1 - 0.0022 17.8 0.0 0.019 14.8 0.0 2.3 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DUF3123 PF11321.3 CBZ54955.1 - 2.2 8.5 7.7 2.9 8.2 3.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3123) MFS_1 PF07690.11 CBZ54956.1 - 4.5e-19 68.3 32.6 6.1e-11 41.6 8.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Pyr_redox_2 PF07992.9 CBZ54959.1 - 7.2e-35 120.6 0.3 1.1e-34 120.0 0.2 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.17 CBZ54959.1 - 6.4e-24 84.1 0.0 1.4e-23 82.9 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.22 CBZ54959.1 - 1.9e-15 57.0 1.0 8.3e-12 45.3 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 CBZ54959.1 - 6e-07 28.6 5.2 0.00014 20.8 2.5 3.0 2 1 0 2 2 2 2 FAD binding domain K_oxygenase PF13434.1 CBZ54959.1 - 3.5e-05 22.8 0.1 0.0026 16.7 0.0 2.6 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.1 CBZ54959.1 - 4.8e-05 23.5 0.1 0.0002 21.4 0.1 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 CBZ54959.1 - 0.00037 20.4 2.6 0.0069 16.3 0.3 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 CBZ54959.1 - 0.0013 17.2 0.5 0.0054 15.2 0.4 1.8 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.2 CBZ54959.1 - 0.0017 17.4 2.5 0.0018 17.4 1.1 1.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.12 CBZ54959.1 - 0.0018 17.4 0.4 0.0034 16.4 0.3 1.4 1 0 0 1 1 1 1 Thi4 family DAO PF01266.19 CBZ54959.1 - 0.012 14.4 2.0 0.012 14.4 1.4 2.0 2 1 0 3 3 3 0 FAD dependent oxidoreductase GIDA PF01134.17 CBZ54959.1 - 0.013 14.4 2.0 0.021 13.6 1.1 1.5 2 0 0 2 2 2 0 Glucose inhibited division protein A 3HCDH_N PF02737.13 CBZ54959.1 - 0.029 14.0 0.3 1.4 8.5 0.3 2.8 3 0 0 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.18 CBZ54959.1 - 0.074 12.7 0.2 0.13 11.9 0.2 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus LSM PF01423.17 CBZ54960.1 - 3.6e-15 55.2 0.7 4.9e-15 54.8 0.5 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 CBZ54960.1 - 7.5e-06 25.7 0.6 1.7e-05 24.6 0.4 1.6 1 1 0 1 1 1 1 Ataxin 2 SM domain ATP-grasp_2 PF08442.5 CBZ54961.1 - 4.7e-65 218.7 0.0 7.5e-65 218.0 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain Ligase_CoA PF00549.14 CBZ54961.1 - 1.2e-19 70.4 0.4 2e-19 69.7 0.3 1.4 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.1 CBZ54961.1 - 1.6e-08 34.0 0.3 9.4e-07 28.2 0.0 2.5 2 1 0 2 2 2 1 ATP-grasp domain OKR_DC_1_N PF03709.10 CBZ54961.1 - 0.0012 18.9 0.1 0.003 17.6 0.0 1.7 1 0 0 1 1 1 1 Orn/Lys/Arg decarboxylase, N-terminal domain Succ_CoA_lig PF13607.1 CBZ54961.1 - 0.015 14.9 0.0 0.033 13.7 0.0 1.6 1 0 0 1 1 1 0 Succinyl-CoA ligase like flavodoxin domain Septin PF00735.13 CBZ54963.1 - 1.9e-05 23.8 0.1 0.012 14.6 0.0 2.2 1 1 1 2 2 2 2 Septin T2SE PF00437.15 CBZ54963.1 - 0.0094 14.8 0.0 0.018 13.9 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein G-alpha PF00503.15 CBZ54963.1 - 0.059 12.0 0.2 0.12 11.0 0.1 1.4 1 0 0 1 1 1 0 G-protein alpha subunit AAA_14 PF13173.1 CBZ54963.1 - 0.32 10.9 0.0 0.7 9.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain Pox_A32 PF04665.7 CBZ54963.1 - 1.1 8.4 0.0 1.8 7.7 0.0 1.2 1 0 0 1 1 1 0 Poxvirus A32 protein Rrp15p PF07890.7 CBZ54964.1 - 2.1e-13 50.4 9.9 2.1e-13 50.4 6.9 2.3 2 1 0 2 2 2 1 Rrp15p RRM_1 PF00076.17 CBZ54966.1 - 9.1e-23 79.6 0.0 1.3e-11 43.9 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBZ54966.1 - 1.2e-20 73.0 0.0 1.8e-11 43.6 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBZ54966.1 - 5.1e-17 61.6 0.0 4e-08 33.1 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Calcipressin PF04847.7 CBZ54966.1 - 7.6e-05 22.3 0.0 0.13 11.8 0.0 2.4 2 0 0 2 2 2 2 Calcipressin Nup35_RRM_2 PF14605.1 CBZ54966.1 - 0.098 12.4 0.1 5.2 6.9 0.0 2.4 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif Ribosomal_60s PF00428.14 CBZ54967.1 - 3.9e-25 88.0 13.2 4.5e-25 87.8 9.1 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein Ribosomal_L5_C PF00673.16 CBZ54968.1 - 2.3e-23 81.7 0.0 3.4e-23 81.2 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.14 CBZ54968.1 - 1.9e-20 72.3 0.2 6.7e-20 70.6 0.0 1.9 2 0 0 2 2 2 1 Ribosomal protein L5 V-SNARE_C PF12352.3 CBZ54968.1 - 0.15 12.1 0.3 1.4 9.0 0.0 2.1 2 0 0 2 2 2 0 Snare region anchored in the vesicle membrane C-terminus Abhydrolase_6 PF12697.2 CBZ54971.1 - 2.7e-24 86.3 0.0 2.5e-21 76.6 0.0 2.4 2 1 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CBZ54971.1 - 3.1e-14 52.9 0.0 8.3e-14 51.5 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 CBZ54971.1 - 2.2e-08 33.8 0.1 5.1e-08 32.6 0.1 1.6 1 0 0 1 1 1 1 Putative lysophospholipase Abhydrolase_1 PF00561.15 CBZ54971.1 - 2.1e-07 30.7 0.0 0.02 14.4 0.0 3.0 3 0 0 3 3 3 2 alpha/beta hydrolase fold Thioesterase PF00975.15 CBZ54971.1 - 0.00067 19.9 0.0 0.017 15.3 0.0 2.3 2 0 0 2 2 2 1 Thioesterase domain PGAP1 PF07819.8 CBZ54971.1 - 0.035 13.6 0.1 0.76 9.3 0.0 2.2 2 0 0 2 2 2 0 PGAP1-like protein Lipase_3 PF01764.20 CBZ54971.1 - 0.067 12.8 0.1 0.13 11.8 0.1 1.4 1 0 0 1 1 1 0 Lipase (class 3) PX PF00787.19 CBZ54972.1 - 3.6e-21 75.0 0.1 1.9e-20 72.7 0.0 2.2 3 0 0 3 3 3 1 PX domain FlgN PF05130.7 CBZ54972.1 - 1.2 9.3 6.1 13 5.9 2.4 2.6 1 1 0 2 2 2 0 FlgN protein Abhydrolase_5 PF12695.2 CBZ54975.1 - 8.2e-22 77.5 0.1 2.4e-21 76.0 0.0 1.9 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 CBZ54975.1 - 0.097 11.8 0.0 0.17 11.0 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family LIP PF03583.9 CBZ54975.1 - 0.15 11.2 0.0 0.32 10.1 0.0 1.5 1 0 0 1 1 1 0 Secretory lipase Abhydrolase_2 PF02230.11 CBZ54975.1 - 0.15 11.4 0.0 0.33 10.3 0.0 1.5 1 1 0 1 1 1 0 Phospholipase/Carboxylesterase DUF818 PF05677.7 CBZ54975.1 - 1.3 7.6 0.0 2.1 6.9 0.0 1.2 1 0 0 1 1 1 0 Chlamydia CHLPS protein (DUF818) Peptidase_C58 PF03543.9 CBZ54976.1 - 6.3 6.2 14.1 0.31 10.5 5.4 1.9 2 0 0 2 2 2 0 Yersinia/Haemophilus virulence surface antigen Activator-TraM PF11657.3 CBZ54977.1 - 0.095 12.1 0.1 0.16 11.4 0.1 1.3 1 0 0 1 1 1 0 Transcriptional activator TraM Melibiase PF02065.13 CBZ54978.1 - 1.4e-06 27.2 0.0 2.5e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 Melibiase PLDc_2 PF13091.1 CBZ54979.1 - 2.2e-18 66.1 0.0 3.1e-09 36.6 0.0 4.1 4 1 0 4 4 4 3 PLD-like domain PLDc PF00614.17 CBZ54979.1 - 9.5e-12 44.3 0.9 2.7e-05 23.7 0.0 2.7 2 0 0 2 2 2 2 Phospholipase D Active site motif Regulator_TrmB PF11495.3 CBZ54979.1 - 0.0088 15.0 0.0 2.4 7.0 0.0 2.2 2 0 0 2 2 2 2 Archaeal transcriptional regulator TrmB WD40 PF00400.27 CBZ54980.1 - 1.7e-17 62.5 15.5 3.3e-06 26.7 0.0 6.3 6 0 0 6 6 6 5 WD domain, G-beta repeat NLE PF08154.7 CBZ54980.1 - 6.3e-16 58.1 0.4 1e-15 57.4 0.3 1.3 1 0 0 1 1 1 1 NLE (NUC135) domain Nup160 PF11715.3 CBZ54980.1 - 0.0036 15.5 0.0 0.095 10.8 0.0 2.4 3 0 0 3 3 3 1 Nucleoporin Nup120/160 KH_1 PF00013.24 CBZ54981.1 - 0.035 13.7 0.0 0.067 12.8 0.0 1.3 1 0 0 1 1 1 0 KH domain Dynein_heavy PF03028.10 CBZ54982.1 - 3.9e-211 702.8 0.0 1.4e-210 701.0 0.0 1.9 2 0 0 2 2 2 1 Dynein heavy chain and region D6 of dynein motor DHC_N2 PF08393.8 CBZ54982.1 - 6.8e-114 380.5 1.3 6.8e-114 380.5 0.9 3.1 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 2 DHC_N1 PF08385.7 CBZ54982.1 - 1.5e-94 317.5 1.3 1.5e-94 317.5 0.9 3.1 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 1 AAA_6 PF12774.2 CBZ54982.1 - 2.2e-94 315.3 0.1 2.8e-93 311.6 0.0 2.3 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region D1 AAA_8 PF12780.2 CBZ54982.1 - 7.2e-55 185.8 0.0 1.6e-54 184.7 0.0 1.6 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_9 PF12781.2 CBZ54982.1 - 1.6e-54 184.1 0.0 3.6e-54 183.0 0.0 1.7 1 0 0 1 1 1 1 ATP-binding dynein motor region D5 AAA_7 PF12775.2 CBZ54982.1 - 4e-54 183.5 0.0 8.1e-53 179.2 0.0 2.6 2 0 0 2 2 2 1 P-loop containing dynein motor region D3 MT PF12777.2 CBZ54982.1 - 3.5e-44 150.9 7.9 6.1e-44 150.1 5.5 1.4 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_5 PF07728.9 CBZ54982.1 - 1.7e-24 86.1 0.1 3e-06 27.0 0.0 6.1 5 1 0 5 5 5 3 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 CBZ54982.1 - 4.9e-08 33.1 0.1 0.48 10.5 0.0 5.7 4 0 0 4 4 4 2 AAA domain FtsK_SpoIIIE PF01580.13 CBZ54982.1 - 1e-05 25.1 0.2 0.03 13.8 0.0 4.8 4 1 0 4 4 4 1 FtsK/SpoIIIE family AAA PF00004.24 CBZ54982.1 - 0.00035 20.7 1.0 0.31 11.2 0.0 4.5 5 0 0 5 5 4 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 CBZ54982.1 - 0.00048 20.9 0.7 2.3 9.0 0.0 5.1 4 0 0 4 4 4 1 AAA domain AAA_19 PF13245.1 CBZ54982.1 - 0.0051 16.5 0.5 1.4 8.7 0.1 3.0 2 0 0 2 2 2 1 Part of AAA domain DUF258 PF03193.11 CBZ54982.1 - 0.036 13.2 0.1 0.69 9.0 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function, DUF258 RNA_helicase PF00910.17 CBZ54982.1 - 0.072 13.2 0.0 21 5.3 0.0 3.3 3 0 0 3 3 2 0 RNA helicase AAA_29 PF13555.1 CBZ54982.1 - 0.089 12.3 0.4 8.6 5.9 0.0 3.1 3 0 0 3 3 3 0 P-loop containing region of AAA domain AAA_18 PF13238.1 CBZ54982.1 - 0.76 10.0 4.7 14 6.0 0.0 4.6 6 0 0 6 6 4 0 AAA domain TisB_toxin PF13939.1 CBZ54983.1 - 0.044 13.4 0.2 0.044 13.4 0.1 1.8 2 0 0 2 2 2 0 Toxin TisB, type I toxin-antitoxin system DUF3938 PF13074.1 CBZ54983.1 - 0.69 9.8 3.7 0.51 10.2 0.8 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3938) DUF1980 PF09323.5 CBZ54983.1 - 0.76 9.4 4.6 6.9 6.3 0.1 2.2 1 1 0 2 2 2 0 Domain of unknown function (DUF1980) DUF3413 PF11893.3 CBZ54983.1 - 1.9 7.2 10.4 2.5 6.9 7.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3413) Lung_7-TM_R PF06814.8 CBZ54984.1 - 2.3e-51 174.5 19.3 2.8e-51 174.2 13.4 1.1 1 0 0 1 1 1 1 Lung seven transmembrane receptor GpcrRhopsn4 PF10192.4 CBZ54984.1 - 9.5e-07 28.2 23.4 2.6e-06 26.8 16.2 1.7 1 1 0 1 1 1 1 Rhodopsin-like GPCR transmembrane domain Sushi PF00084.15 CBZ54985.1 - 0.00057 20.1 0.1 0.0012 19.1 0.0 1.6 1 0 0 1 1 1 1 Sushi domain (SCR repeat) CAP_C PF08603.6 CBZ54987.1 - 2.8e-54 182.7 4.7 3.5e-54 182.4 3.3 1.1 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal TBCC PF07986.7 CBZ54987.1 - 2.7e-07 30.0 3.5 4.9e-07 29.1 2.4 1.4 1 0 0 1 1 1 1 Tubulin binding cofactor C Crisp PF08562.5 CBZ54987.1 - 0.055 13.7 0.6 0.055 13.7 0.4 1.9 2 0 0 2 2 2 0 Crisp Coat_X PF07552.6 CBZ54987.1 - 2.2 8.1 5.2 27 4.6 0.0 3.2 2 1 1 3 3 3 0 Spore Coat Protein X and V domain UQ_con PF00179.21 CBZ54988.1 - 7e-16 57.9 0.0 8e-16 57.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 CBZ54988.1 - 0.068 13.0 0.0 0.069 13.0 0.0 1.2 1 0 0 1 1 1 0 RWD domain RRM_1 PF00076.17 CBZ54990.1 - 3.1e-31 106.8 0.3 1.2e-14 53.7 0.1 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBZ54990.1 - 2.9e-28 97.6 0.2 4.9e-15 55.2 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBZ54990.1 - 1e-08 34.8 0.2 0.00043 20.0 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NID PF07292.8 CBZ54990.1 - 0.039 13.9 0.0 0.13 12.3 0.0 1.8 2 0 0 2 2 2 0 Nmi/IFP 35 domain (NID) RRM_3 PF08777.6 CBZ54990.1 - 0.039 13.7 0.4 0.59 9.9 0.1 2.1 1 1 1 2 2 2 0 RNA binding motif MoeA_N PF03453.12 CBZ54990.1 - 0.15 11.3 1.6 0.18 11.1 0.1 1.8 2 0 0 2 2 2 0 MoeA N-terminal region (domain I and II) RNase_T PF00929.19 CBZ54991.1 - 1.5e-29 103.4 0.1 1.9e-29 103.0 0.1 1.2 1 0 0 1 1 1 1 Exonuclease Methyltransf_31 PF13847.1 CBZ54992.1 - 1.9e-15 56.7 0.0 2.3e-15 56.4 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CBZ54992.1 - 1.1e-14 54.9 0.0 1.5e-14 54.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CBZ54992.1 - 6.6e-14 52.1 0.1 9.8e-14 51.6 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CBZ54992.1 - 9.5e-11 41.6 0.0 1.2e-10 41.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CBZ54992.1 - 4.5e-09 36.6 0.0 6.3e-09 36.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CBZ54992.1 - 1.9e-08 34.5 0.2 3.8e-08 33.6 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain TPMT PF05724.6 CBZ54992.1 - 1.9e-06 27.5 0.0 6.8e-06 25.6 0.0 1.7 1 1 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Ubie_methyltran PF01209.13 CBZ54992.1 - 2.1e-06 27.0 0.0 3.1e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family CMAS PF02353.15 CBZ54992.1 - 5.5e-05 22.3 0.0 6.9e-05 22.0 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase TehB PF03848.9 CBZ54992.1 - 0.00089 18.4 0.1 0.0012 18.0 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB MTS PF05175.9 CBZ54992.1 - 0.0042 16.4 0.0 0.0071 15.7 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 CBZ54992.1 - 0.0089 16.0 0.0 0.033 14.2 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain ThiF PF00899.16 CBZ54992.1 - 0.011 15.5 0.0 0.02 14.7 0.0 1.4 1 0 0 1 1 1 0 ThiF family N6_N4_Mtase PF01555.13 CBZ54992.1 - 0.016 14.7 0.0 0.024 14.1 0.0 1.2 1 0 0 1 1 1 0 DNA methylase Methyltransf_8 PF05148.10 CBZ54992.1 - 0.032 13.8 0.3 0.26 10.9 0.2 2.0 1 1 0 1 1 1 0 Hypothetical methyltransferase AMP-binding PF00501.23 CBZ54993.1 - 7.3e-56 189.3 0.0 5.1e-55 186.5 0.0 2.4 1 1 0 1 1 1 1 AMP-binding enzyme Mannosyl_trans PF05007.8 CBZ54994.1 - 1.4e-60 205.1 23.3 1.7e-43 149.1 12.3 2.2 2 0 0 2 2 2 2 Mannosyltransferase (PIG-M) Pol_alpha_B_N PF08418.5 CBZ54994.1 - 1.3 8.5 8.3 1.9 7.9 5.7 1.1 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal DAP3 PF10236.4 CBZ54995.1 - 1.6e-27 96.2 0.0 1.5e-13 50.3 0.0 2.3 2 0 0 2 2 2 2 Mitochondrial ribosomal death-associated protein 3 Spc97_Spc98 PF04130.8 CBZ54996.1 - 1.2e-67 228.5 0.0 1.7e-52 178.4 0.0 3.1 3 0 0 3 3 3 3 Spc97 / Spc98 family Phasin_2 PF09361.5 CBZ54996.1 - 1.6 8.8 6.5 0.39 10.7 0.2 3.0 3 0 0 3 3 3 0 Phasin protein AMP-binding PF00501.23 CBZ54998.1 - 7.9e-71 238.6 0.0 1.2e-70 238.0 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Piwi PF02171.12 CBZ54999.1 - 5.8e-50 169.9 0.0 8.6e-50 169.4 0.0 1.3 1 0 0 1 1 1 1 Piwi domain PAZ PF02170.17 CBZ54999.1 - 0.00015 21.0 0.0 0.0003 20.0 0.0 1.4 1 0 0 1 1 1 1 PAZ domain Pkinase PF00069.20 CBZ55002.1 - 2.4e-09 36.7 0.0 1.5e-08 34.1 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain WD40 PF00400.27 CBZ55002.1 - 6.9e-08 32.0 0.1 0.059 13.2 0.0 4.5 4 0 0 4 4 4 2 WD domain, G-beta repeat HEAT PF02985.17 CBZ55002.1 - 2.8e-07 30.0 16.2 0.0012 18.7 0.1 6.2 5 0 0 5 5 5 2 HEAT repeat HEAT_2 PF13646.1 CBZ55002.1 - 0.00085 19.5 14.6 0.0077 16.4 0.1 4.9 5 0 0 5 5 5 2 HEAT repeats Pkinase_Tyr PF07714.12 CBZ55002.1 - 0.018 14.1 0.0 0.23 10.4 0.0 2.0 2 0 0 2 2 2 0 Protein tyrosine kinase Kinase-like PF14531.1 CBZ55002.1 - 3 6.6 0.1 5.3 5.9 0.0 1.2 1 0 0 1 1 1 0 Kinase-like LacY_symp PF01306.14 CBZ55004.1 - 0.0011 17.5 1.6 0.0011 17.5 1.1 2.2 2 0 0 2 2 2 2 LacY proton/sugar symporter PHP_C PF13263.1 CBZ55004.1 - 0.059 12.8 0.6 0.2 11.1 0.0 2.1 2 0 0 2 2 2 0 PHP-associated GBP PF02263.14 CBZ55005.1 - 1.2e-14 53.9 0.1 1.3e-12 47.3 0.0 3.4 3 1 0 3 3 3 1 Guanylate-binding protein, N-terminal domain Prominin PF05478.6 CBZ55005.1 - 0.64 7.4 0.6 0.93 6.9 0.4 1.1 1 0 0 1 1 1 0 Prominin DUF641 PF04859.7 CBZ55005.1 - 0.72 9.6 11.1 1.2 8.8 1.8 2.4 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) MMR1 PF08505.5 CBZ55006.1 - 0.11 12.4 2.7 0.19 11.7 1.9 1.4 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein Rhabdo_ncap PF00945.13 CBZ55006.1 - 0.18 10.3 1.3 0.26 9.8 0.9 1.2 1 0 0 1 1 1 0 Rhabdovirus nucleocapsid protein Bestrophin PF01062.16 CBZ55007.1 - 2.9e-14 52.6 8.3 1.6e-06 27.3 2.2 3.0 3 0 0 3 3 3 3 Bestrophin, RFP-TM, chloride channel Mic1 PF07035.7 CBZ55009.1 - 0.00093 18.6 0.1 0.0025 17.1 0.1 1.7 1 1 0 1 1 1 1 Colon cancer-associated protein Mic1-like CTP_transf_2 PF01467.21 CBZ55010.1 - 1.9e-32 112.5 0.0 1.5e-15 57.6 0.0 2.4 2 0 0 2 2 2 2 Cytidylyltransferase FAD_syn PF06574.7 CBZ55010.1 - 0.0011 18.6 0.6 0.97 9.0 0.1 2.8 2 1 0 2 2 2 2 FAD synthetase Pantoate_ligase PF02569.10 CBZ55010.1 - 0.19 10.4 0.0 11 4.6 0.0 2.1 2 0 0 2 2 2 0 Pantoate-beta-alanine ligase RCC1_2 PF13540.1 CBZ55011.1 - 2e-25 87.7 11.4 6.4e-08 32.0 0.9 6.0 6 0 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.13 CBZ55011.1 - 6.2e-19 67.9 10.8 0.0062 16.7 0.0 8.1 7 1 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat WD40 PF00400.27 CBZ55013.1 - 8.5e-20 69.8 4.4 2.9e-05 23.7 0.0 7.8 7 1 0 7 7 7 5 WD domain, G-beta repeat PQQ_2 PF13360.1 CBZ55013.1 - 0.0056 16.1 0.0 3.7 6.9 0.0 3.4 3 1 0 3 3 3 2 PQQ-like domain Calreticulin PF00262.13 CBZ55014.1 - 2.1e-53 181.2 0.0 1.3e-44 152.3 0.0 2.4 3 0 0 3 3 3 2 Calreticulin family MAR_sialic_bdg PF10564.4 CBZ55016.1 - 3.8e-29 100.3 14.9 7.2e-22 77.0 2.4 2.7 1 1 1 2 2 2 2 Sialic-acid binding micronemal adhesive repeat PGAP1 PF07819.8 CBZ55017.1 - 4.4e-06 26.4 0.0 8.9e-06 25.4 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein LCAT PF02450.10 CBZ55017.1 - 0.11 11.3 0.0 0.18 10.7 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase DUF676 PF05057.9 CBZ55017.1 - 1.2 8.3 0.0 3.7 6.7 0.0 1.7 2 0 0 2 2 2 0 Putative serine esterase (DUF676) MAR_sialic_bdg PF10564.4 CBZ55019.1 - 3.7e-33 113.2 20.1 1.3e-22 79.4 3.2 2.3 1 1 1 2 2 2 2 Sialic-acid binding micronemal adhesive repeat MotA_ExbB PF01618.11 CBZ55020.1 - 2.8 7.5 5.9 0.37 10.3 0.4 2.1 2 0 0 2 2 2 0 MotA/TolQ/ExbB proton channel family Brix PF04427.13 CBZ55021.1 - 3.9e-35 121.2 0.2 1e-30 106.7 0.0 2.2 1 1 1 2 2 2 2 Brix domain Ran-binding PF05508.6 CBZ55021.1 - 0.11 11.3 0.0 0.19 10.6 0.0 1.3 1 0 0 1 1 1 0 RanGTP-binding protein EMP70 PF02990.11 CBZ55022.1 - 0.54 8.6 3.7 0.2 10.0 0.6 1.6 1 1 0 2 2 2 0 Endomembrane protein 70 Glyco_transf_8 PF01501.15 CBZ55023.1 - 2.6e-20 72.8 0.0 6.1e-19 68.3 0.0 2.5 1 1 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.3 CBZ55023.1 - 0.11 11.7 0.0 0.3 10.3 0.0 1.8 1 1 0 1 1 1 0 Mannosyltransferase putative WD40 PF00400.27 CBZ55024.1 - 3e-29 99.7 16.5 8.3e-05 22.3 0.0 10.3 9 2 0 9 9 9 8 WD domain, G-beta repeat CT47 PF15623.1 CBZ55025.1 - 0.46 10.1 26.0 0.61 9.7 18.0 1.1 1 0 0 1 1 1 0 Cancer/testis gene family 47 Mucin PF01456.12 CBZ55025.1 - 1.8 8.3 11.2 2.3 7.9 7.7 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein DGF-1_C PF11040.3 CBZ55025.1 - 2.1 8.2 6.6 1.1 9.2 3.1 1.7 1 1 1 2 2 2 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus Mitofilin PF09731.4 CBZ55025.1 - 8.9 4.8 16.1 9.4 4.7 11.2 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein HSP90 PF00183.13 CBZ55026.1 - 5.3e-118 394.7 0.0 1.6e-77 261.1 0.1 3.6 3 1 0 3 3 3 3 Hsp90 protein HATPase_c_3 PF13589.1 CBZ55026.1 - 1.3e-11 44.2 0.1 2.4e-11 43.4 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 CBZ55026.1 - 3.2e-09 36.4 0.0 7.9e-09 35.2 0.0 1.7 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MIase PF02426.11 CBZ55026.1 - 0.033 13.9 0.9 0.089 12.6 0.1 2.1 2 0 0 2 2 2 0 Muconolactone delta-isomerase CwfJ_C_2 PF04676.9 CBZ55026.1 - 0.26 11.7 0.1 0.26 11.7 0.1 3.3 4 0 0 4 4 4 0 Protein similar to CwfJ C-terminus 2 MORN PF02493.15 CBZ55027.1 - 1.3e-97 314.0 99.5 1.3e-09 37.1 1.0 15.0 15 0 0 15 15 15 14 MORN repeat IncA PF04156.9 CBZ55028.1 - 0.0025 17.4 15.6 0.0025 17.4 10.8 9.3 4 3 5 10 10 10 6 IncA protein PgaD PF13994.1 CBZ55028.1 - 9.2 5.7 6.5 6.9 6.1 0.3 2.8 2 0 0 2 2 2 0 PgaD-like protein Ras PF00071.17 CBZ55029.1 - 6e-58 194.7 0.2 6.8e-58 194.6 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CBZ55029.1 - 1.2e-18 67.7 0.0 1.9e-18 67.0 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CBZ55029.1 - 1.6e-15 56.7 0.1 2e-15 56.4 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 CBZ55029.1 - 4.8e-06 26.1 0.0 1.6e-05 24.4 0.0 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 CBZ55029.1 - 6.2e-05 22.2 0.0 7.6e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 CBZ55029.1 - 0.00031 20.0 0.0 0.0004 19.6 0.0 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 CBZ55029.1 - 0.00086 19.2 0.0 0.0012 18.7 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase COX2 PF00116.15 CBZ55030.1 - 1.1e-37 128.5 0.0 1.5e-37 128.1 0.0 1.2 1 0 0 1 1 1 1 Cytochrome C oxidase subunit II, periplasmic domain ParcG PF10274.4 CBZ55031.1 - 9.7e-62 208.1 0.0 1.3e-61 207.7 0.0 1.1 1 0 0 1 1 1 1 Parkin co-regulated protein Ribosomal_L18e PF00828.14 CBZ55032.1 - 5.3e-35 120.6 0.4 7.3e-35 120.1 0.3 1.2 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 PDEase_I PF00233.14 CBZ55035.1 - 2e-45 155.3 0.3 3.1e-45 154.7 0.2 1.2 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase Helicase_C PF00271.26 CBZ55036.1 - 1e-06 28.5 0.0 2.5e-06 27.2 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-RING_2 PF13639.1 CBZ55036.1 - 0.00015 21.4 7.6 0.00069 19.3 5.3 2.2 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 CBZ55036.1 - 0.00099 18.7 4.8 0.00099 18.7 3.4 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CBZ55036.1 - 0.0015 18.1 4.9 0.0015 18.1 3.4 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBZ55036.1 - 0.0045 16.6 4.0 0.0045 16.6 2.8 2.5 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 CBZ55036.1 - 0.51 10.4 11.7 0.061 13.3 3.5 2.6 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Pex14_N PF04695.8 CBZ55036.1 - 0.58 10.2 9.5 0.046 13.7 2.5 2.2 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region zf-RING_4 PF14570.1 CBZ55036.1 - 1.5 8.5 9.9 2 8.0 2.1 2.5 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain SNF2_N PF00176.18 CBZ55037.1 - 1.2e-35 122.8 0.0 7.2e-31 107.0 0.0 2.7 2 1 0 2 2 2 2 SNF2 family N-terminal domain PHD PF00628.24 CBZ55037.1 - 0.0064 16.1 2.3 0.02 14.5 1.6 1.9 1 0 0 1 1 1 1 PHD-finger PKD_channel PF08016.7 CBZ55038.1 - 8e-07 27.8 57.9 0.00018 20.0 10.7 4.4 5 0 0 5 5 5 3 Polycystin cation channel PRTase_3 PF15610.1 CBZ55038.1 - 0.14 11.0 0.1 0.24 10.2 0.1 1.2 1 0 0 1 1 1 0 PRTase ComF-like RRM_6 PF14259.1 CBZ55039.1 - 0.00016 21.5 0.0 0.00047 20.0 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBZ55039.1 - 0.0041 16.9 0.0 0.0092 15.8 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CBZ55039.1 - 0.0072 15.9 0.0 0.022 14.3 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Cnd2 PF05786.9 CBZ55039.1 - 0.72 8.2 7.0 1.1 7.7 4.8 1.1 1 0 0 1 1 1 0 Condensin complex subunit 2 Glyco_hydro_16 PF00722.16 CBZ55040.1 - 3.1e-05 23.3 0.0 5.5e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 HSBP1 PF06825.7 CBZ55041.1 - 2.4e-14 52.6 2.0 3.8e-14 52.0 1.4 1.2 1 0 0 1 1 1 1 Heat shock factor binding protein 1 UPF0184 PF03670.8 CBZ55041.1 - 0.071 13.2 0.2 0.13 12.4 0.2 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0184) CBM_20 PF00686.14 CBZ55043.1 - 7.4e-13 47.9 0.0 1.5e-12 46.9 0.0 1.4 1 0 0 1 1 1 1 Starch binding domain DUF773 PF05600.7 CBZ55044.1 - 2.4e-37 128.8 3.5 8.5e-29 100.6 0.2 3.2 2 1 0 2 2 2 2 Protein of unknown function (DUF773) IncA PF04156.9 CBZ55044.1 - 0.0096 15.5 8.2 0.082 12.4 2.2 2.5 2 0 0 2 2 2 1 IncA protein Spectrin PF00435.16 CBZ55044.1 - 0.018 15.2 1.5 0.018 15.2 1.0 3.3 3 0 0 3 3 3 0 Spectrin repeat HTH_6 PF01418.12 CBZ55044.1 - 0.091 12.5 0.5 0.57 9.9 0.2 2.4 1 1 1 2 2 2 0 Helix-turn-helix domain, rpiR family Spc24 PF08286.6 CBZ55044.1 - 0.18 11.5 2.2 3.1 7.5 0.2 2.7 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 Atg14 PF10186.4 CBZ55044.1 - 0.21 10.5 8.9 0.44 9.4 1.1 2.2 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Prefoldin_2 PF01920.15 CBZ55044.1 - 0.23 11.2 10.2 0.16 11.7 1.1 3.0 2 1 1 3 3 3 0 Prefoldin subunit Cep57_MT_bd PF06657.8 CBZ55044.1 - 0.5 10.3 5.4 0.55 10.2 0.2 3.3 3 1 1 4 4 4 0 Centrosome microtubule-binding domain of Cep57 CENP-Q PF13094.1 CBZ55044.1 - 0.75 9.8 10.2 5.5 7.0 1.9 2.8 2 1 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Sec8_exocyst PF04048.9 CBZ55044.1 - 1.5 8.4 8.5 0.83 9.2 0.5 3.5 4 0 0 4 4 4 0 Sec8 exocyst complex component specific domain ParBc PF02195.13 CBZ55044.1 - 1.5 9.0 4.2 4.1 7.5 0.0 3.1 2 1 0 3 3 3 0 ParB-like nuclease domain GAS PF13851.1 CBZ55044.1 - 4.4 6.4 9.4 2.6 7.1 2.8 2.3 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding DivIC PF04977.10 CBZ55044.1 - 4.9 6.7 9.6 0.47 9.9 1.0 2.6 2 0 0 2 2 2 0 Septum formation initiator SlyX PF04102.7 CBZ55044.1 - 8.6 6.8 8.0 36 4.8 0.4 3.4 4 0 0 4 4 3 0 SlyX PNP_UDP_1 PF01048.15 CBZ55045.1 - 6.2e-38 130.0 0.1 7.8e-38 129.7 0.0 1.2 1 0 0 1 1 1 1 Phosphorylase superfamily NIF PF03031.13 CBZ55046.1 - 3.3e-26 91.8 0.0 5.3e-26 91.1 0.0 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Phosphorylase PF00343.15 CBZ55047.1 - 0 1040.7 0.4 0 1040.4 0.2 1.0 1 0 0 1 1 1 1 Carbohydrate phosphorylase Pox_F11 PF04943.7 CBZ55047.1 - 0.0069 15.2 0.1 0.016 14.0 0.0 1.5 1 0 0 1 1 1 1 Poxvirus F11 protein Aminotran_1_2 PF00155.16 CBZ55048.1 - 0.093 11.6 0.0 0.38 9.6 0.0 1.9 2 1 1 3 3 3 0 Aminotransferase class I and II DUF2076 PF09849.4 CBZ55049.1 - 0.0053 16.8 0.7 0.0061 16.6 0.5 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) Prefoldin PF02996.12 CBZ55049.1 - 0.0057 16.2 0.3 0.0078 15.8 0.2 1.2 1 0 0 1 1 1 1 Prefoldin subunit SlyX PF04102.7 CBZ55049.1 - 0.0092 16.3 0.9 0.017 15.4 0.7 1.3 1 0 0 1 1 1 1 SlyX CCDC155 PF14662.1 CBZ55049.1 - 0.027 14.0 0.4 0.036 13.6 0.2 1.1 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 DUF4140 PF13600.1 CBZ55049.1 - 0.052 14.0 1.0 0.084 13.3 0.7 1.4 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) DUF3373 PF11853.3 CBZ55049.1 - 0.15 10.5 0.3 0.18 10.3 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) Flg_hook PF02120.11 CBZ55049.1 - 0.2 11.3 2.2 0.33 10.6 1.6 1.3 1 0 0 1 1 1 0 Flagellar hook-length control protein FliK Metallophos PF00149.23 CBZ55050.1 - 2.4e-45 154.3 0.4 2.9e-45 154.1 0.3 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Rsm22 PF09243.5 CBZ55051.1 - 2.3e-74 249.8 0.2 2.5e-62 210.4 0.0 2.1 2 0 0 2 2 2 2 Mitochondrial small ribosomal subunit Rsm22 Cir_N PF10197.4 CBZ55052.1 - 0.16 12.0 0.0 0.16 12.0 0.0 3.3 4 0 0 4 4 4 0 N-terminal domain of CBF1 interacting co-repressor CIR Viral_P18 PF04521.8 CBZ55052.1 - 0.18 11.2 12.4 0.99 8.8 2.2 3.1 3 0 0 3 3 3 0 ssRNA positive strand viral 18kD cysteine rich protein Prominin PF05478.6 CBZ55052.1 - 0.33 8.4 0.2 0.59 7.6 0.2 1.3 1 0 0 1 1 1 0 Prominin TMEM247 PF15444.1 CBZ55052.1 - 0.34 10.6 0.5 1.1 9.0 0.4 1.8 1 0 0 1 1 1 0 Transmembrane protein 247 Sipho_Gp157 PF05565.6 CBZ55052.1 - 0.46 10.0 0.5 0.77 9.3 0.4 1.3 1 0 0 1 1 1 0 Siphovirus Gp157 DUF972 PF06156.8 CBZ55052.1 - 2 8.7 3.0 38 4.6 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF972) HTH_29 PF13551.1 CBZ55053.1 - 0.005 16.9 0.7 0.019 15.0 0.5 2.0 1 0 0 1 1 1 1 Winged helix-turn helix HalX PF08663.5 CBZ55053.1 - 0.37 10.8 6.7 0.91 9.5 0.5 3.4 3 0 0 3 3 3 0 HalX domain FlxA PF14282.1 CBZ55053.1 - 0.66 9.9 3.0 6.4 6.7 0.3 3.0 3 0 0 3 3 3 0 FlxA-like protein EMP24_GP25L PF01105.19 CBZ55055.1 - 9.2e-23 80.8 0.0 1.2e-22 80.4 0.0 1.2 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Cwf_Cwc_15 PF04889.7 CBZ55055.1 - 0.053 13.2 1.6 0.084 12.5 1.1 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein PP2C PF00481.16 CBZ55056.1 - 7.7e-48 163.1 0.0 6.1e-41 140.4 0.0 2.0 1 1 1 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.1 CBZ55056.1 - 0.00028 20.3 0.7 0.00049 19.5 0.5 1.6 1 1 0 1 1 1 1 Protein phosphatase 2C DUF533 PF04391.7 CBZ55058.1 - 0.014 14.8 1.0 0.022 14.1 0.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF533) Closter_coat PF01785.12 CBZ55058.1 - 0.19 10.7 0.0 0.33 9.9 0.0 1.3 1 0 0 1 1 1 0 Closterovirus coat protein YlbD_coat PF14071.1 CBZ55059.1 - 0.0073 16.3 1.2 0.0073 16.3 0.9 2.1 1 1 1 2 2 2 1 Putative coat protein DUF2096 PF09869.4 CBZ55059.1 - 0.015 15.2 0.7 0.19 11.5 0.1 2.2 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2096) Peptidase_M9_N PF08453.5 CBZ55059.1 - 0.041 13.2 0.2 0.056 12.7 0.1 1.2 1 0 0 1 1 1 0 Peptidase family M9 N-terminal TRAP_alpha PF03896.11 CBZ55059.1 - 0.1 11.5 1.6 0.18 10.8 1.1 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit TPR_5 PF12688.2 CBZ55059.1 - 0.11 12.5 0.0 0.27 11.2 0.0 1.6 1 0 0 1 1 1 0 Tetratrico peptide repeat Cir_Bir_Yir PF06022.6 CBZ55059.1 - 0.17 11.1 0.8 0.24 10.5 0.5 1.3 1 0 0 1 1 1 0 Plasmodium variant antigen protein Cir/Yir/Bir Flagellin_N PF00669.15 CBZ55059.1 - 0.18 11.6 0.4 6 6.6 0.0 2.4 1 1 2 3 3 3 0 Bacterial flagellin N-terminal helical region Sigma70_ner PF04546.8 CBZ55059.1 - 0.23 11.0 10.9 0.4 10.2 7.6 1.4 1 1 0 1 1 1 0 Sigma-70, non-essential region PBP1_TM PF14812.1 CBZ55059.1 - 1 9.7 5.0 2.1 8.7 3.5 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Adaptin_binding PF10199.4 CBZ55059.1 - 1.1 9.5 10.6 0.2 11.9 4.2 1.9 1 1 1 2 2 2 0 Alpha and gamma adaptin binding protein p34 Glyco_hydro_17 PF00332.13 CBZ55059.1 - 1.1 8.1 3.0 17 4.3 0.0 2.0 1 1 1 2 2 2 0 Glycosyl hydrolases family 17 CENP-B_dimeris PF09026.5 CBZ55059.1 - 5.1 7.4 13.9 7.7 6.8 8.9 1.9 1 1 1 2 2 2 0 Centromere protein B dimerisation domain CRAL_TRIO PF00650.15 CBZ55060.1 - 9.1e-28 96.7 0.0 1.2e-27 96.3 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.1 CBZ55060.1 - 0.00017 21.5 0.0 0.00026 20.9 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Cytochrom_B_N PF00033.14 CBZ55060.1 - 0.033 13.5 0.0 7.4 5.8 0.0 2.3 2 0 0 2 2 2 0 Cytochrome b(N-terminal)/b6/petB DUF1700 PF08006.6 CBZ55060.1 - 5.8 6.1 7.0 10 5.3 4.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) Apyrase PF06079.6 CBZ55061.1 - 3.7e-68 229.8 0.0 3.3e-37 128.2 0.0 2.1 1 1 1 2 2 2 2 Apyrase Slu7 PF11708.3 CBZ55062.1 - 4.2e-72 242.7 16.7 4.2e-72 242.7 11.5 2.0 2 1 0 2 2 2 1 Pre-mRNA splicing Prp18-interacting factor zf-CCHC_4 PF14392.1 CBZ55062.1 - 1.6 8.4 5.0 0.33 10.6 0.4 2.2 3 0 0 3 3 3 0 Zinc knuckle Atrophin-1 PF03154.10 CBZ55062.1 - 6.9 4.6 12.5 11 3.9 8.7 1.2 1 0 0 1 1 1 0 Atrophin-1 family ECH PF00378.15 CBZ55063.1 - 4.7e-44 150.3 0.0 5.3e-34 117.4 0.0 2.0 2 0 0 2 2 2 2 Enoyl-CoA hydratase/isomerase family DUF4191 PF13829.1 CBZ55064.1 - 0.025 13.6 0.0 0.034 13.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) RseC_MucC PF04246.7 CBZ55064.1 - 0.03 13.8 3.4 0.048 13.2 2.4 1.2 1 0 0 1 1 1 0 Positive regulator of sigma(E), RseC/MucC DUF4131 PF13567.1 CBZ55064.1 - 0.097 12.0 2.1 0.12 11.7 1.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) Nucleos_tra2_N PF01773.15 CBZ55064.1 - 0.12 12.7 0.9 0.19 12.0 0.6 1.3 1 0 0 1 1 1 0 Na+ dependent nucleoside transporter N-terminus zf-MYND PF01753.13 CBZ55065.1 - 9.5e-12 44.5 8.6 1.6e-11 43.8 6.0 1.4 1 0 0 1 1 1 1 MYND finger DUF3846 PF12957.2 CBZ55065.1 - 0.042 13.5 0.0 0.07 12.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3846) WD40 PF00400.27 CBZ55066.1 - 2.6e-54 179.2 14.7 7.1e-09 35.2 0.0 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Nucleoporin_N PF08801.6 CBZ55066.1 - 0.0022 16.8 0.1 0.11 11.2 0.0 2.1 2 0 0 2 2 2 2 Nup133 N terminal like eIF2A PF08662.6 CBZ55066.1 - 0.018 14.7 0.0 1.2 8.8 0.0 2.6 1 1 1 2 2 2 0 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 CBZ55066.1 - 0.021 12.9 0.4 0.49 8.4 0.0 2.6 1 1 2 3 3 3 0 Nucleoporin Nup120/160 PQQ_2 PF13360.1 CBZ55066.1 - 0.023 14.1 1.2 0.062 12.7 0.8 1.8 1 1 0 1 1 1 0 PQQ-like domain AP2 PF00847.15 CBZ55067.1 - 1.3e-11 44.4 7.4 4.7e-07 29.8 1.1 2.5 2 0 0 2 2 2 2 AP2 domain WD40 PF00400.27 CBZ55068.1 - 3.2e-08 33.1 6.4 6.6e-06 25.8 0.2 4.3 4 0 0 4 4 4 2 WD domain, G-beta repeat AP2 PF00847.15 CBZ55070.1 - 1.8e-07 31.2 0.3 1.8e-07 31.2 0.2 2.5 3 0 0 3 3 3 1 AP2 domain FrhB_FdhB_N PF04422.8 CBZ55070.1 - 0.0026 17.6 0.8 0.95 9.3 0.1 2.9 2 0 0 2 2 2 2 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit N-term PAT1 PF09770.4 CBZ55070.1 - 2 6.5 20.3 4.1 5.5 14.1 1.4 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 ATP-synt_F PF01990.12 CBZ55071.1 - 1.9e-30 105.0 0.2 2.4e-30 104.7 0.1 1.1 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit Cwf_Cwc_15 PF04889.7 CBZ55074.1 - 0.00047 19.9 15.7 0.00052 19.7 10.9 1.1 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein Pox_Ag35 PF03286.9 CBZ55074.1 - 0.0017 17.9 15.0 0.002 17.7 10.4 1.2 1 0 0 1 1 1 1 Pox virus Ag35 surface protein TFIIF_alpha PF05793.7 CBZ55074.1 - 0.007 14.7 25.5 0.0092 14.4 17.7 1.1 1 0 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) SRP-alpha_N PF04086.8 CBZ55074.1 - 0.011 15.1 16.2 0.015 14.6 11.2 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal FLO_LFY PF01698.11 CBZ55074.1 - 0.018 13.8 10.0 0.021 13.6 6.9 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein Baculo_PP31 PF05311.6 CBZ55074.1 - 0.025 13.8 15.1 0.037 13.3 10.4 1.2 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) Y_phosphatase3 PF13350.1 CBZ55074.1 - 0.025 14.8 1.2 0.078 13.2 0.0 2.0 2 0 0 2 2 2 0 Tyrosine phosphatase family Macoilin PF09726.4 CBZ55074.1 - 0.029 12.6 13.9 0.028 12.7 9.6 1.1 1 0 0 1 1 1 0 Transmembrane protein DUF1754 PF08555.5 CBZ55074.1 - 0.094 13.3 33.7 2.4 8.8 23.4 2.3 1 1 0 1 1 1 0 Eukaryotic family of unknown function (DUF1754) GAGA_bind PF06217.7 CBZ55074.1 - 0.15 11.9 12.7 0.17 11.7 8.8 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family DUF1168 PF06658.7 CBZ55074.1 - 0.21 11.1 24.5 0.4 10.1 17.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) FAM60A PF15396.1 CBZ55074.1 - 0.21 11.3 21.9 0.091 12.4 13.7 1.4 2 0 0 2 2 2 0 Protein Family FAM60A DUF3807 PF12720.2 CBZ55074.1 - 0.3 11.2 16.0 0.4 10.8 11.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) NARP1 PF12569.3 CBZ55074.1 - 0.32 9.7 16.5 0.38 9.4 11.5 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Sec3_C PF09763.4 CBZ55074.1 - 0.35 8.9 13.0 0.46 8.5 9.0 1.1 1 0 0 1 1 1 0 Exocyst complex component Sec3 Peptidase_S49_N PF08496.5 CBZ55074.1 - 0.41 10.4 9.3 0.63 9.8 6.5 1.5 1 0 0 1 1 1 0 Peptidase family S49 N-terminal RR_TM4-6 PF06459.7 CBZ55074.1 - 0.46 10.3 10.3 0.54 10.1 7.2 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CobT PF06213.7 CBZ55074.1 - 0.53 9.3 11.9 0.6 9.1 8.3 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF2413 PF10310.4 CBZ55074.1 - 0.61 8.8 17.5 0.73 8.5 12.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) DUF2201_N PF13203.1 CBZ55074.1 - 0.62 9.1 9.5 0.73 8.9 6.6 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain Vfa1 PF08432.5 CBZ55074.1 - 0.65 9.9 22.2 1 9.3 15.4 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Zip PF02535.17 CBZ55074.1 - 1.1 8.2 5.7 1.1 8.2 3.9 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter YL1 PF05764.8 CBZ55074.1 - 1.2 8.6 23.4 1.9 8.0 16.2 1.2 1 0 0 1 1 1 0 YL1 nuclear protein NPR3 PF03666.8 CBZ55074.1 - 1.4 7.3 20.8 2.2 6.7 14.4 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Paramyxo_ncap PF00973.14 CBZ55074.1 - 1.6 7.3 8.1 1.8 7.1 5.6 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein CDK2AP PF09806.4 CBZ55074.1 - 1.9 8.7 10.9 2.7 8.1 7.5 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein DUF1510 PF07423.6 CBZ55074.1 - 2.5 7.4 21.5 3.5 6.9 14.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) MIP-T3 PF10243.4 CBZ55074.1 - 3.5 6.0 27.8 4.7 5.5 19.3 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 SelP_N PF04592.9 CBZ55074.1 - 3.5 6.9 12.8 5.2 6.3 8.9 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Hid1 PF12722.2 CBZ55074.1 - 4.2 4.9 11.3 4.6 4.8 7.8 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF3513 PF12026.3 CBZ55074.1 - 5.1 6.5 12.6 8.3 5.8 8.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3513) CDC45 PF02724.9 CBZ55074.1 - 5.3 4.9 18.5 7.1 4.5 12.8 1.2 1 0 0 1 1 1 0 CDC45-like protein HHV6-IE PF03753.8 CBZ55074.1 - 6 4.2 20.3 8 3.7 14.1 1.1 1 0 0 1 1 1 0 Human herpesvirus 6 immediate early protein MFMR PF07777.6 CBZ55074.1 - 8.1 6.3 21.0 13 5.6 14.6 1.3 1 0 0 1 1 1 0 G-box binding protein MFMR Rtf2 PF04641.7 CBZ55074.1 - 8.2 5.5 21.5 13 4.9 14.9 1.3 1 0 0 1 1 1 0 Rtf2 RING-finger U3snoRNP10 PF12397.3 CBZ55077.1 - 4.3e-21 75.0 4.1 4.3e-21 75.0 2.9 4.6 5 0 0 5 5 5 1 U3 small nucleolar RNA-associated protein 10 HD PF01966.17 CBZ55079.1 - 1.2e-09 38.2 0.0 3.7e-07 30.1 0.0 2.5 2 0 0 2 2 2 2 HD domain DUF1580 PF07618.6 CBZ55079.1 - 0.049 12.9 0.6 0.11 11.8 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1580) RRM_5 PF13893.1 CBZ55080.1 - 0.0042 16.8 0.0 0.0078 16.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Chlorovi_GP_rpt PF06598.6 CBZ55080.1 - 0.41 10.5 2.8 1.3 8.9 1.9 1.8 1 0 0 1 1 1 0 Chlorovirus glycoprotein repeat RAB3GAP2_C PF14656.1 CBZ55080.1 - 0.82 7.7 0.1 1.2 7.1 0.1 1.1 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit C-terminus Ion_trans PF00520.26 CBZ55081.1 - 6.3e-21 74.5 17.1 1.1e-16 60.6 5.3 2.4 2 0 0 2 2 2 2 Ion transport protein UCH PF00443.24 CBZ55082.1 - 9.1e-35 120.0 0.0 1.3e-34 119.5 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CBZ55082.1 - 4.8e-06 26.2 0.0 0.067 12.6 0.0 2.6 3 0 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase zf-CCCH PF00642.19 CBZ55083.1 - 5e-08 32.4 13.2 1.3e-05 24.7 0.5 4.0 3 1 0 3 3 3 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Ufm1 PF03671.9 CBZ55084.1 - 3e-40 135.8 0.3 3.4e-40 135.6 0.2 1.0 1 0 0 1 1 1 1 Ubiquitin fold modifier 1 protein Mak10 PF04112.8 CBZ55085.1 - 0.00024 20.3 0.0 0.43 9.7 0.0 2.5 2 0 0 2 2 2 2 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase Apt1 PF10351.4 CBZ55085.1 - 8 5.2 6.8 1.2 7.8 1.2 2.1 2 0 0 2 2 2 0 Golgi-body localisation protein domain SURF1 PF02104.10 CBZ55086.1 - 3.3e-26 92.4 1.8 1e-20 74.4 2.0 3.0 2 1 0 2 2 2 2 SURF1 family PWI PF01480.12 CBZ55087.1 - 4.2e-26 90.8 0.1 6.5e-26 90.2 0.0 1.3 1 0 0 1 1 1 1 PWI domain PYC_OADA PF02436.13 CBZ55087.1 - 0.047 13.1 0.1 0.071 12.5 0.1 1.3 1 0 0 1 1 1 0 Conserved carboxylase domain BAAT_C PF08840.6 CBZ55088.1 - 0.099 12.3 0.1 0.14 11.8 0.1 1.2 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal TauE PF01925.14 CBZ55090.1 - 7.2e-19 68.1 45.0 8e-11 41.8 5.9 3.2 3 0 0 3 3 3 2 Sulfite exporter TauE/SafE DUF3053 PF11254.3 CBZ55091.1 - 0.26 10.4 0.7 0.49 9.6 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3053) DnaJ PF00226.26 CBZ55092.1 - 5.9e-26 89.9 1.2 2.5e-25 87.9 1.0 2.0 2 0 0 2 2 2 1 DnaJ domain CTDII PF01556.13 CBZ55092.1 - 4.8e-22 77.6 0.4 4.8e-21 74.4 0.0 2.8 4 0 0 4 4 4 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 CBZ55092.1 - 4e-14 52.4 15.5 8.2e-14 51.4 10.7 1.6 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.14 CBZ55092.1 - 0.00011 21.8 4.7 0.025 14.2 0.1 2.4 2 0 0 2 2 2 2 Hydrogenase expression/synthesis hypA family zf-RING_3 PF14369.1 CBZ55092.1 - 6.3 6.8 10.7 35 4.5 0.0 3.6 3 1 1 4 4 4 0 zinc-finger NRDD PF13597.1 CBZ55092.1 - 6.4 4.7 5.9 0.95 7.4 0.2 2.1 1 1 1 2 2 2 0 Anaerobic ribonucleoside-triphosphate reductase BTB PF00651.26 CBZ55093.1 - 7.1e-08 32.4 0.0 1.4e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain DUF755 PF05501.6 CBZ55093.1 - 1.3 9.1 7.1 0.073 13.1 0.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF755) EF-hand_7 PF13499.1 CBZ55094.1 - 0.00032 20.7 0.0 0.0014 18.6 0.0 1.9 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 CBZ55094.1 - 0.0059 15.8 0.4 0.025 13.8 0.0 2.3 3 0 0 3 3 3 1 EF hand DUF515 PF04415.7 CBZ55094.1 - 0.14 10.3 0.0 0.17 10.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) PTPLA PF04387.9 CBZ55096.1 - 1.6e-47 160.9 9.3 1.7e-26 92.6 1.8 2.3 2 0 0 2 2 2 2 Protein tyrosine phosphatase-like protein, PTPLA Y_phosphatase PF00102.22 CBZ55096.1 - 0.07 12.4 0.0 0.13 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein-tyrosine phosphatase cNMP_binding PF00027.24 CBZ55097.1 - 3.8e-43 145.1 0.1 9.1e-22 76.6 0.0 2.4 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain RIIa PF02197.12 CBZ55097.1 - 0.0036 16.6 0.0 0.01 15.2 0.0 1.7 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit PBP1_TM PF14812.1 CBZ55097.1 - 3.5 8.0 6.5 0.42 10.9 1.5 1.7 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Metallophos PF00149.23 CBZ55098.1 - 3.8e-40 137.4 0.1 6.7e-40 136.6 0.1 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 CBZ55098.1 - 0.019 14.7 0.0 0.026 14.3 0.0 1.2 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain V-SNARE PF05008.10 CBZ55099.1 - 0.0024 17.9 1.4 0.0024 17.9 1.0 2.1 2 0 0 2 2 2 1 Vesicle transport v-SNARE protein N-terminus DUF4140 PF13600.1 CBZ55099.1 - 0.062 13.7 2.5 7.7 7.0 0.1 2.4 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) DUF2580 PF10824.3 CBZ55099.1 - 0.066 13.5 0.6 0.31 11.4 0.2 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF2580) FliT PF05400.8 CBZ55099.1 - 0.13 12.6 0.1 0.13 12.6 0.1 2.6 3 0 0 3 3 3 0 Flagellar protein FliT Spc7 PF08317.6 CBZ55099.1 - 0.23 10.0 2.2 0.34 9.5 1.5 1.3 1 1 0 1 1 1 0 Spc7 kinetochore protein Syntaxin PF00804.20 CBZ55099.1 - 0.28 11.3 2.3 1.2 9.3 1.6 1.9 1 1 0 1 1 1 0 Syntaxin Sec2p PF06428.6 CBZ55099.1 - 0.47 10.3 3.3 0.77 9.6 0.2 2.1 2 0 0 2 2 2 0 GDP/GTP exchange factor Sec2p DSPc PF00782.15 CBZ55100.1 - 2.7e-18 65.8 0.0 4.2e-18 65.2 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain cNMP_binding PF00027.24 CBZ55101.1 - 1.3e-69 230.0 1.9 6e-21 74.0 0.0 4.5 4 0 0 4 4 4 4 Cyclic nucleotide-binding domain Pkinase PF00069.20 CBZ55101.1 - 2.7e-68 229.9 0.0 4.6e-68 229.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ55101.1 - 2.6e-31 108.6 0.0 5.4e-31 107.6 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBZ55101.1 - 5.5e-08 32.1 0.2 2.1e-07 30.2 0.0 2.0 3 0 0 3 3 3 1 Kinase-like Cupin_2 PF07883.6 CBZ55101.1 - 4.6e-05 22.8 0.3 4.1 6.9 0.0 4.2 4 0 0 4 4 4 2 Cupin domain Kdo PF06293.9 CBZ55101.1 - 0.0022 17.1 0.0 0.0046 16.0 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CBZ55101.1 - 0.009 15.7 0.0 0.031 14.0 0.0 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family Aldedh PF00171.17 CBZ55102.1 - 1.4e-68 231.3 0.0 7.3e-38 130.0 0.0 2.0 2 0 0 2 2 2 2 Aldehyde dehydrogenase family LuxC PF05893.9 CBZ55102.1 - 0.014 14.1 0.0 0.075 11.7 0.0 1.9 2 0 0 2 2 2 0 Acyl-CoA reductase (LuxC) tRNA_m1G_MT PF01746.16 CBZ55104.1 - 1.2e-23 83.6 0.1 3.3e-21 75.7 0.0 2.3 2 0 0 2 2 2 2 tRNA (Guanine-1)-methyltransferase WD40 PF00400.27 CBZ55105.1 - 6.7e-06 25.7 1.4 0.27 11.1 0.0 4.5 3 0 0 3 3 3 2 WD domain, G-beta repeat Prp18 PF02840.10 CBZ55105.1 - 0.0038 17.0 0.3 0.0079 16.0 0.2 1.5 1 0 0 1 1 1 1 Prp18 domain SRA1 PF07304.6 CBZ55105.1 - 0.05 13.3 0.1 0.05 13.3 0.0 2.1 2 0 0 2 2 2 0 Steroid receptor RNA activator (SRA1) Mpp10 PF04006.7 CBZ55106.1 - 1.1e-45 156.1 93.7 3.6e-32 111.5 7.1 3.3 2 1 0 2 2 2 2 Mpp10 protein Fibrillarin PF01269.12 CBZ55108.1 - 4.4e-112 372.5 0.0 5.2e-112 372.3 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.5 CBZ55108.1 - 0.00015 21.3 0.0 0.00022 20.8 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_31 PF13847.1 CBZ55108.1 - 0.0071 15.9 0.0 0.0095 15.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain DREV PF05219.7 CBZ55108.1 - 0.044 12.6 0.0 0.069 12.0 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase Methyltransf_18 PF12847.2 CBZ55108.1 - 0.06 13.9 0.0 0.1 13.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.14 CBZ55108.1 - 0.078 12.5 0.1 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) SAG PF04092.8 CBZ55109.1 - 2.3e-11 44.1 0.0 3.3e-11 43.6 0.0 1.3 1 0 0 1 1 1 1 SRS domain zf-C2H2 PF00096.21 CBZ55110.1 - 1.9e-21 75.0 47.3 0.00014 21.9 2.4 7.4 7 0 0 7 7 7 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CBZ55110.1 - 1.6e-17 62.4 44.8 0.00016 21.7 0.9 7.5 7 0 0 7 7 7 6 C2H2-type zinc finger zf-C2H2_6 PF13912.1 CBZ55110.1 - 2.5e-08 33.5 22.2 0.0074 16.1 0.1 5.5 6 0 0 6 6 6 3 C2H2-type zinc finger zf-H2C2_2 PF13465.1 CBZ55110.1 - 0.00042 20.4 52.8 0.091 13.0 1.2 9.4 9 1 0 9 9 9 3 Zinc-finger double domain FYVE PF01363.16 CBZ55110.1 - 0.0031 17.3 1.3 0.0031 17.3 0.9 4.0 3 1 1 4 4 4 1 FYVE zinc finger Zn-ribbon_8 PF09723.5 CBZ55110.1 - 0.006 16.5 19.0 0.65 9.9 2.5 5.1 3 2 1 4 4 4 2 Zinc ribbon domain HypA PF01155.14 CBZ55110.1 - 0.074 12.7 6.4 0.21 11.2 0.5 2.7 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family zf-C2H2_jaz PF12171.3 CBZ55110.1 - 0.12 12.5 0.1 0.12 12.5 0.1 5.5 6 0 0 6 6 6 0 Zinc-finger double-stranded RNA-binding TFIIS_C PF01096.13 CBZ55110.1 - 0.65 9.6 16.0 0.43 10.2 1.5 3.9 3 1 1 4 4 4 0 Transcription factor S-II (TFIIS) Lar_restr_allev PF14354.1 CBZ55110.1 - 1.2 9.4 7.8 0.32 11.3 0.2 3.1 3 0 0 3 3 3 0 Restriction alleviation protein Lar zf-met PF12874.2 CBZ55110.1 - 1.6 9.0 13.0 3.2 8.0 0.2 4.7 5 0 0 5 5 5 0 Zinc-finger of C2H2 type ADK_lid PF05191.9 CBZ55110.1 - 1.7 8.3 9.9 11 5.7 0.0 4.3 3 1 0 3 3 3 0 Adenylate kinase, active site lid NinF PF05810.7 CBZ55110.1 - 1.7 8.4 12.3 3.7 7.4 0.1 4.2 4 1 1 5 5 5 0 NinF protein zinc_ribbon_5 PF13719.1 CBZ55110.1 - 3 7.4 13.4 26 4.4 0.1 4.5 4 0 0 4 4 4 0 zinc-ribbon domain GATA PF00320.22 CBZ55110.1 - 4 6.8 10.5 4.5 6.6 0.6 3.9 3 1 1 4 4 4 0 GATA zinc finger zinc_ribbon_4 PF13717.1 CBZ55110.1 - 5.1 6.8 14.0 33 4.2 0.1 4.6 4 0 0 4 4 4 0 zinc-ribbon domain zf-C2H2_3 PF13878.1 CBZ55110.1 - 7.1 6.2 8.6 2.2 7.9 0.1 3.7 4 0 0 4 4 4 0 zinc-finger of acetyl-transferase ESCO ThiF PF00899.16 CBZ55114.1 - 7.4e-30 103.5 0.0 2.1e-21 76.1 0.0 2.4 2 0 0 2 2 2 2 ThiF family UBACT PF02134.16 CBZ55114.1 - 1.5e-25 88.5 0.1 2.9e-25 87.6 0.1 1.5 1 0 0 1 1 1 1 Repeat in ubiquitin-activating (UBA) protein UAE_UbL PF14732.1 CBZ55114.1 - 3.9e-19 68.5 0.0 8.5e-19 67.4 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain UBA_e1_thiolCys PF10585.4 CBZ55114.1 - 2.8e-18 65.0 0.4 6.2e-18 63.9 0.3 1.6 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site Shikimate_DH PF01488.15 CBZ55114.1 - 0.0012 18.9 0.0 0.0029 17.7 0.0 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.1 CBZ55114.1 - 0.0086 16.3 0.1 0.16 12.2 0.0 2.7 2 1 0 2 2 2 1 Putative NAD(P)-binding Pkinase PF00069.20 CBZ55115.1 - 9.5e-38 129.8 0.0 1.3e-19 70.3 0.0 3.2 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ55115.1 - 1.3e-17 63.7 0.0 2.5e-08 33.3 0.0 3.1 3 0 0 3 3 3 2 Protein tyrosine kinase Kdo PF06293.9 CBZ55115.1 - 0.00015 20.8 0.0 0.00031 19.8 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CBZ55115.1 - 0.042 13.5 0.0 0.084 12.5 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kinase-like PF14531.1 CBZ55115.1 - 0.13 11.2 0.0 12 4.7 0.0 2.2 2 0 0 2 2 2 0 Kinase-like WD40 PF00400.27 CBZ55116.1 - 3.2e-10 39.4 8.6 0.00036 20.3 0.0 5.6 5 0 0 5 5 5 3 WD domain, G-beta repeat Bromodomain PF00439.20 CBZ55116.1 - 4e-05 23.4 0.0 8e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Bromodomain OAF PF14941.1 CBZ55116.1 - 2.8 7.0 5.0 16 4.5 0.4 2.2 2 0 0 2 2 2 0 Transcriptional regulator, Out at first LRR_4 PF12799.2 CBZ55117.1 - 2.8e-08 33.1 7.4 0.0012 18.4 1.0 2.4 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 CBZ55117.1 - 1.2e-06 27.9 7.5 0.049 13.7 0.0 4.3 4 0 0 4 4 4 2 Leucine Rich repeat LRR_8 PF13855.1 CBZ55117.1 - 0.00035 20.2 8.8 0.038 13.7 1.1 2.9 2 1 0 2 2 2 2 Leucine rich repeat LRR_1 PF00560.28 CBZ55117.1 - 0.0018 18.0 12.1 3 8.2 0.3 5.0 4 0 0 4 4 4 2 Leucine Rich Repeat LRR_7 PF13504.1 CBZ55117.1 - 0.0036 17.2 10.4 1.1 9.7 0.0 5.1 5 0 0 5 5 5 1 Leucine rich repeat SET PF00856.23 CBZ55118.1 - 3.6e-18 66.3 0.2 3.6e-18 66.3 0.1 4.1 3 2 0 3 3 3 1 SET domain FUN14 PF04930.10 CBZ55120.1 - 1.2e-17 64.0 0.0 2.3e-17 63.1 0.0 1.5 1 0 0 1 1 1 1 FUN14 family Peptidase_C97 PF05903.9 CBZ55121.1 - 7.1e-39 132.9 0.0 1.3e-38 132.1 0.0 1.3 1 0 0 1 1 1 1 PPPDE putative peptidase domain PUB PF09409.5 CBZ55121.1 - 5.5e-12 45.2 0.1 1.1e-10 41.0 0.0 2.3 2 0 0 2 2 2 1 PUB domain UBA PF00627.26 CBZ55121.1 - 1.8e-06 27.5 1.1 5.4e-06 26.0 0.4 2.0 2 0 0 2 2 2 1 UBA/TS-N domain DUF770 PF05591.7 CBZ55121.1 - 0.015 14.8 0.0 0.029 13.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF770) CUE PF02845.11 CBZ55121.1 - 0.077 12.4 0.2 0.15 11.6 0.1 1.5 1 0 0 1 1 1 0 CUE domain Di19_C PF14571.1 CBZ55122.1 - 0.0036 17.5 2.6 2.7 8.3 0.1 3.2 2 0 0 2 2 2 2 Stress-induced protein Di19, C-terminal HSP70 PF00012.15 CBZ55124.1 - 1.9e-263 874.8 14.9 2.2e-263 874.6 10.3 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 CBZ55124.1 - 9.7e-21 73.6 1.3 9.7e-21 73.6 0.9 2.5 3 0 0 3 3 3 1 MreB/Mbl protein FGGY_C PF02782.11 CBZ55124.1 - 0.0015 18.1 0.0 0.003 17.2 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.1 CBZ55124.1 - 0.073 12.9 8.8 3.5 7.4 0.0 4.4 3 1 0 3 3 3 0 Cell division protein FtsA Hydantoinase_A PF01968.13 CBZ55124.1 - 0.074 12.1 4.2 0.087 11.9 0.1 2.8 2 1 1 3 3 3 0 Hydantoinase/oxoprolinase DUF3287 PF11690.3 CBZ55124.1 - 0.2 11.7 2.3 5.3 7.1 1.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3287) Effector_1 PF04518.7 CBZ55124.1 - 1.1 8.2 8.1 0.16 10.9 1.0 2.2 2 0 0 2 2 2 0 Effector from type III secretion system Lactamase_B_2 PF12706.2 CBZ55125.1 - 4.1e-05 23.2 0.0 0.00014 21.4 0.0 1.8 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 CBZ55125.1 - 0.19 11.3 4.5 0.11 12.1 1.2 1.9 2 0 0 2 2 2 0 Metallo-beta-lactamase superfamily Mucin PF01456.12 CBZ55126.1 - 0.017 14.8 0.4 0.076 12.7 0.3 2.1 1 0 0 1 1 1 0 Mucin-like glycoprotein Drf_DAD PF06345.6 CBZ55126.1 - 0.21 11.4 4.5 0.13 12.0 0.2 2.7 2 0 0 2 2 2 0 DRF Autoregulatory Domain Mago-bind PF09282.5 CBZ55127.1 - 4.3e-14 51.7 10.1 4.6e-14 51.6 3.8 2.7 2 0 0 2 2 2 1 Mago binding AAA_23 PF13476.1 CBZ55127.1 - 0.0058 16.9 0.4 0.0061 16.8 0.3 1.2 1 0 0 1 1 1 1 AAA domain Ead_Ea22 PF13935.1 CBZ55127.1 - 0.039 14.2 2.9 0.06 13.6 2.0 1.4 1 0 0 1 1 1 0 Ead/Ea22-like protein IncA PF04156.9 CBZ55127.1 - 0.061 12.9 11.6 0.83 9.2 3.1 2.2 2 0 0 2 2 2 0 IncA protein Pox_A_type_inc PF04508.7 CBZ55127.1 - 0.079 12.7 9.9 1.7 8.6 1.4 3.0 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat Fmp27_WPPW PF10359.4 CBZ55127.1 - 0.21 9.9 4.1 0.27 9.6 2.9 1.2 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain FlxA PF14282.1 CBZ55127.1 - 0.88 9.5 9.9 0.73 9.8 5.2 2.1 1 1 1 2 2 2 0 FlxA-like protein Syntaxin-6_N PF09177.6 CBZ55127.1 - 1.3 9.4 5.0 1.5 9.2 2.3 2.0 1 1 1 2 2 2 0 Syntaxin 6, N-terminal DUF2408 PF10303.4 CBZ55127.1 - 1.9 8.6 7.8 5.1 7.2 3.6 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2408) Cluap1 PF10234.4 CBZ55127.1 - 2.4 7.2 8.1 3.1 6.9 5.6 1.1 1 0 0 1 1 1 0 Clusterin-associated protein-1 Enkurin PF13864.1 CBZ55127.1 - 2.4 8.4 15.2 2.2 8.5 7.2 2.5 2 1 1 3 3 3 0 Calmodulin-binding Bap31 PF05529.7 CBZ55127.1 - 2.5 7.5 6.3 0.57 9.5 1.9 1.7 1 1 1 2 2 2 0 B-cell receptor-associated protein 31-like V_ATPase_I PF01496.14 CBZ55127.1 - 3 5.5 4.1 3.6 5.3 2.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Occludin_ELL PF07303.8 CBZ55127.1 - 3.5 8.4 6.6 26 5.6 1.4 2.3 1 1 1 2 2 2 0 Occludin homology domain TPR_MLP1_2 PF07926.7 CBZ55127.1 - 5.1 6.8 12.5 9.4 5.9 8.0 1.9 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein APG6 PF04111.7 CBZ55127.1 - 7.4 5.5 10.0 9.2 5.2 7.0 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF4519 PF15012.1 CBZ55129.1 - 0.045 13.6 0.0 0.083 12.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4519) ADH_zinc_N PF00107.21 CBZ55131.1 - 1e-23 83.3 0.0 1.9e-23 82.4 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 CBZ55131.1 - 9.3e-17 60.7 2.2 9.3e-17 60.7 1.5 2.0 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 CBZ55131.1 - 5.5e-05 24.0 0.0 0.00013 22.8 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase UDPG_MGDP_dh_N PF03721.9 CBZ55131.1 - 0.0068 15.8 0.0 0.011 15.1 0.0 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain TrkA_N PF02254.13 CBZ55131.1 - 0.022 14.7 0.0 0.039 13.9 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain AlaDh_PNT_C PF01262.16 CBZ55131.1 - 0.025 14.1 1.1 0.095 12.2 0.1 2.1 1 1 1 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.14 CBZ55131.1 - 0.047 12.8 0.0 0.076 12.1 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ELFV_dehydrog PF00208.16 CBZ55131.1 - 0.086 12.4 0.1 0.15 11.6 0.1 1.2 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase PCI PF01399.22 CBZ55132.1 - 0.00088 19.5 0.0 0.19 12.0 0.0 2.3 2 0 0 2 2 2 2 PCI domain DUF1666 PF07891.7 CBZ55132.1 - 0.15 11.4 0.0 0.22 10.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1666) Exo_endo_phos PF03372.18 CBZ55133.1 - 0.013 15.4 0.0 0.18 11.6 0.0 2.3 1 1 1 2 2 2 0 Endonuclease/Exonuclease/phosphatase family PPTA PF01239.17 CBZ55134.1 - 0.0058 15.9 0.1 0.29 10.5 0.0 2.7 2 0 0 2 2 2 2 Protein prenyltransferase alpha subunit repeat TMF_TATA_bd PF12325.3 CBZ55136.1 - 0.00032 20.4 4.0 0.00054 19.6 2.8 1.4 1 0 0 1 1 1 1 TATA element modulatory factor 1 TATA binding Atg14 PF10186.4 CBZ55136.1 - 0.0031 16.4 5.0 0.0031 16.4 3.5 1.1 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 KLRAQ PF10205.4 CBZ55136.1 - 0.012 15.6 6.5 0.012 15.6 4.5 1.8 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein Ribosomal_L30 PF00327.15 CBZ55136.1 - 0.022 14.3 0.0 0.042 13.4 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein L30p/L7e DivIC PF04977.10 CBZ55136.1 - 0.059 12.8 2.5 0.095 12.1 1.7 1.5 1 0 0 1 1 1 0 Septum formation initiator Ax_dynein_light PF10211.4 CBZ55136.1 - 0.11 12.3 5.5 0.16 11.7 3.8 1.2 1 0 0 1 1 1 0 Axonemal dynein light chain FliJ PF02050.11 CBZ55136.1 - 0.11 12.5 14.8 0.17 11.9 10.3 1.3 1 0 0 1 1 1 0 Flagellar FliJ protein APG6 PF04111.7 CBZ55136.1 - 0.15 11.0 2.1 0.16 10.9 1.5 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 Seryl_tRNA_N PF02403.17 CBZ55136.1 - 0.17 11.8 9.0 0.048 13.6 4.0 1.8 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain TPR_MLP1_2 PF07926.7 CBZ55136.1 - 0.19 11.4 7.5 0.36 10.5 5.2 1.4 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein DUF4407 PF14362.1 CBZ55136.1 - 1.4 7.7 4.5 1.5 7.7 3.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) FlxA PF14282.1 CBZ55136.1 - 1.8 8.5 7.2 0.6 10.0 3.0 1.7 1 1 1 2 2 2 0 FlxA-like protein DUF789 PF05623.7 CBZ55138.1 - 4.3e-16 59.2 1.1 7.2e-09 35.5 0.0 3.1 2 1 0 2 2 2 2 Protein of unknown function (DUF789) DUF2777 PF10949.3 CBZ55138.1 - 0.2 11.3 0.1 0.36 10.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2777) WD40 PF00400.27 CBZ55139.1 - 3e-22 77.6 11.0 4.8e-06 26.2 0.3 6.3 6 0 0 6 6 6 5 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 CBZ55139.1 - 1.4e-16 60.1 0.0 4.4e-16 58.5 0.0 1.9 2 0 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex Apc4_WD40 PF12894.2 CBZ55139.1 - 0.057 12.9 0.0 7.9 6.0 0.0 3.5 4 0 0 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain Prion_bPrPp PF11587.3 CBZ55139.1 - 0.071 12.7 0.4 0.94 9.2 0.1 2.4 2 0 0 2 2 2 0 Major prion protein bPrPp - N terminal Bd3614-deam PF14439.1 CBZ55139.1 - 1.2 8.9 4.5 14 5.5 0.0 2.6 2 0 0 2 2 2 0 Bd3614-like deaminase BACK PF07707.10 CBZ55140.1 - 0.0005 19.8 0.0 0.012 15.3 0.0 2.7 3 0 0 3 3 3 1 BTB And C-terminal Kelch Bd3614_N PF14442.1 CBZ55141.1 - 0.0033 17.3 3.1 0.0063 16.4 2.2 1.4 1 0 0 1 1 1 1 Bd3614-like deaminase N-terminal CorA PF01544.13 CBZ55141.1 - 2.6 7.0 8.9 4.2 6.3 6.1 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein DUF2392 PF10288.4 CBZ55142.1 - 1e-09 38.6 0.0 7.6e-09 35.8 0.0 2.2 1 1 0 1 1 1 1 Protein of unknown function (DUF2392) ATP_bind_3 PF01171.15 CBZ55142.1 - 0.011 15.2 0.0 2.5 7.5 0.0 2.3 2 0 0 2 2 2 0 PP-loop family Macoilin PF09726.4 CBZ55142.1 - 0.047 11.9 13.8 0.075 11.3 9.6 1.4 1 0 0 1 1 1 0 Transmembrane protein DUF2217 PF10265.4 CBZ55142.1 - 0.68 8.6 14.6 1.2 7.8 10.1 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) MIP-T3 PF10243.4 CBZ55142.1 - 2.4 6.5 12.3 0.1 11.0 4.6 1.5 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 DNA_pol_viral_N PF00242.12 CBZ55142.1 - 5.7 5.8 16.0 11 4.9 11.1 1.5 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain Cwf_Cwc_15 PF04889.7 CBZ55142.1 - 7.3 6.2 10.3 29 4.2 7.1 2.0 1 1 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein GRAM PF02893.15 CBZ55143.1 - 5.9e-10 38.5 0.1 1e-09 37.7 0.1 1.4 1 0 0 1 1 1 1 GRAM domain SH3_2 PF07653.12 CBZ55143.1 - 0.023 14.1 0.1 0.067 12.6 0.1 1.8 1 0 0 1 1 1 0 Variant SH3 domain Ras PF00071.17 CBZ55144.1 - 1.1e-59 200.4 0.0 1.3e-59 200.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CBZ55144.1 - 8.9e-17 61.6 0.0 1.4e-16 61.0 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CBZ55144.1 - 9.3e-12 44.5 0.0 1.2e-11 44.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 CBZ55144.1 - 0.0003 20.7 0.0 0.00049 20.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 CBZ55144.1 - 0.0012 18.0 0.0 0.0014 17.7 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 CBZ55144.1 - 0.0032 16.9 0.0 0.018 14.4 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_24 PF13479.1 CBZ55144.1 - 0.079 12.5 0.0 0.15 11.5 0.0 1.4 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.1 CBZ55144.1 - 0.096 12.8 0.0 0.23 11.5 0.0 1.8 2 1 0 2 2 2 0 AAA domain CAF-1_p150 PF11600.3 CBZ55145.1 - 0.0011 18.4 33.4 0.0011 18.4 23.1 11.0 6 2 3 9 9 9 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal Ribosomal_L14 PF00238.14 CBZ55146.1 - 8.4e-32 109.4 0.0 9.4e-32 109.3 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e E1-E2_ATPase PF00122.15 CBZ55147.1 - 2.5e-56 190.3 0.0 6.3e-56 188.9 0.0 1.9 1 1 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 CBZ55147.1 - 1.4e-33 115.9 0.2 1.4e-33 115.9 0.1 3.3 4 0 0 4 4 4 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 CBZ55147.1 - 2.2e-27 96.9 0.0 1.9e-26 93.8 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 CBZ55147.1 - 2.9e-13 50.4 4.4 8.3e-13 48.9 3.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 CBZ55147.1 - 7.9e-13 48.1 0.0 1.6e-12 47.1 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 CBZ55147.1 - 4.3e-06 26.0 0.0 1.2e-05 24.7 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 CBZ55147.1 - 2.7e-05 23.8 0.6 0.00018 21.1 0.3 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Thioredoxin_8 PF13905.1 CBZ55148.1 - 1e-45 153.7 0.0 1e-26 92.8 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_2 PF13098.1 CBZ55148.1 - 1.9e-12 47.3 0.0 2.1e-07 31.1 0.0 2.9 3 0 0 3 3 3 2 Thioredoxin-like domain Thioredoxin PF00085.15 CBZ55148.1 - 9.2e-09 34.9 0.0 4.8e-06 26.1 0.0 2.9 2 1 1 3 3 3 2 Thioredoxin Redoxin PF08534.5 CBZ55148.1 - 1e-07 31.6 0.0 1.2e-06 28.1 0.0 2.2 2 0 0 2 2 2 1 Redoxin AhpC-TSA PF00578.16 CBZ55148.1 - 2e-07 30.7 0.0 3.2e-05 23.6 0.0 2.6 2 0 0 2 2 2 1 AhpC/TSA family SCO1-SenC PF02630.9 CBZ55148.1 - 1.4e-05 24.7 0.0 5.1e-05 22.9 0.0 1.9 2 0 0 2 2 2 1 SCO1/SenC Thioredoxin_7 PF13899.1 CBZ55148.1 - 0.00071 19.5 0.0 0.0065 16.4 0.0 2.3 2 0 0 2 2 2 1 Thioredoxin-like Glutaredoxin PF00462.19 CBZ55148.1 - 0.011 15.7 0.1 0.42 10.6 0.0 3.2 2 1 0 2 2 2 0 Glutaredoxin Thioredoxin_9 PF14595.1 CBZ55148.1 - 0.025 14.1 0.0 0.24 10.9 0.0 2.6 2 1 0 2 2 2 0 Thioredoxin Thioredoxin_6 PF13848.1 CBZ55148.1 - 0.21 11.3 0.2 40 3.9 0.0 3.5 4 0 0 4 4 4 0 Thioredoxin-like domain RNase_Zc3h12a PF11977.3 CBZ55149.1 - 1e-10 41.6 0.0 2.3e-05 24.3 0.0 2.6 2 1 0 2 2 2 2 Zc3h12a-like Ribonuclease NYN domain zf-C2H2_4 PF13894.1 CBZ55149.1 - 2.5 8.6 7.0 0.67 10.4 0.2 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger zf-H2C2_2 PF13465.1 CBZ55149.1 - 8.9 6.8 10.2 3.8 7.9 0.4 3.6 3 0 0 3 3 3 0 Zinc-finger double domain GED PF02212.13 CBZ55150.1 - 0.19 11.6 0.0 0.33 10.8 0.0 1.2 1 0 0 1 1 1 0 Dynamin GTPase effector domain Podoplanin PF05808.6 CBZ55151.1 - 0.018 14.5 0.7 0.041 13.4 0.5 1.6 1 0 0 1 1 1 0 Podoplanin Cohesin_HEAT PF12765.2 CBZ55154.1 - 0.0019 18.1 2.7 2.4 8.1 0.8 3.4 3 0 0 3 3 3 2 HEAT repeat associated with sister chromatid cohesion HEAT PF02985.17 CBZ55154.1 - 0.66 10.2 11.8 11 6.4 0.0 5.7 6 0 0 6 6 6 0 HEAT repeat Metallophos PF00149.23 CBZ55155.1 - 2.9e-36 124.7 0.1 4.4e-36 124.1 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase TPR_11 PF13414.1 CBZ55155.1 - 1.3e-17 63.2 2.9 4e-12 45.6 0.1 2.8 2 1 1 3 3 3 2 TPR repeat PPP5 PF08321.7 CBZ55155.1 - 5.1e-13 48.8 0.0 1.3e-12 47.5 0.0 1.7 1 0 0 1 1 1 1 PPP5 TPR repeat region TPR_2 PF07719.12 CBZ55155.1 - 5.8e-12 44.5 2.2 1.6e-05 24.4 0.2 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 CBZ55155.1 - 2.2e-11 42.8 7.8 1.6e-05 24.2 1.2 3.9 4 0 0 4 4 3 2 Tetratricopeptide repeat DUF3808 PF10300.4 CBZ55155.1 - 2.2e-05 23.2 2.1 3.1e-05 22.7 1.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) TPR_17 PF13431.1 CBZ55155.1 - 0.0015 18.5 0.2 0.0055 16.7 0.1 2.0 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_9 PF13371.1 CBZ55155.1 - 0.0065 16.2 0.1 0.022 14.6 0.0 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 CBZ55155.1 - 0.01 15.7 0.4 0.078 12.9 0.0 2.2 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.1 CBZ55155.1 - 0.016 14.9 0.0 1.9 8.4 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.1 CBZ55155.1 - 0.033 13.9 0.0 1.1 9.1 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat Tim17 PF02466.14 CBZ55156.1 - 8e-30 103.5 2.2 1.2e-29 102.8 1.6 1.3 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family DUF4235 PF14019.1 CBZ55156.1 - 0.12 12.2 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4235) DNA_topoisoIV PF00521.15 CBZ55157.1 - 1.2e-125 419.6 0.0 2e-125 419.0 0.0 1.3 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A DNA_gyraseB PF00204.20 CBZ55157.1 - 1.1e-30 106.1 1.6 2.5e-30 104.9 1.1 1.6 1 0 0 1 1 1 1 DNA gyrase B Toprim PF01751.17 CBZ55157.1 - 2.8e-14 52.8 0.0 1e-13 51.1 0.0 2.0 1 0 0 1 1 1 1 Toprim domain HATPase_c PF02518.21 CBZ55157.1 - 3.5e-07 29.9 0.1 3.5e-06 26.7 0.0 2.4 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase TFIIS_C PF01096.13 CBZ55158.1 - 4.3e-19 67.8 9.1 4.3e-19 67.8 6.3 3.5 3 1 1 4 4 4 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.11 CBZ55158.1 - 7.8e-08 31.8 1.1 7.8e-08 31.8 0.7 2.5 3 0 0 3 3 2 1 RNA polymerases M/15 Kd subunit Zn_Tnp_IS1595 PF12760.2 CBZ55158.1 - 0.0024 17.6 13.5 0.063 13.0 4.2 2.3 2 0 0 2 2 2 2 Transposase zinc-ribbon domain DUF2387 PF09526.5 CBZ55158.1 - 0.015 15.2 8.6 0.34 10.8 0.9 2.2 1 1 1 2 2 2 0 Probable metal-binding protein (DUF2387) zf-H2C2_5 PF13909.1 CBZ55158.1 - 0.026 14.7 0.7 0.026 14.7 0.5 3.6 4 0 0 4 4 3 0 C2H2-type zinc-finger domain Baculo_LEF5_C PF11792.3 CBZ55158.1 - 0.036 13.4 2.8 0.036 13.4 2.0 2.3 3 0 0 3 3 3 0 Baculoviridae late expression factor 5 C-terminal domain zinc-ribbons_6 PF07191.7 CBZ55158.1 - 0.039 13.7 0.8 0.039 13.7 0.5 2.5 2 1 0 2 2 2 0 zinc-ribbons zinc_ribbon_4 PF13717.1 CBZ55158.1 - 0.068 12.8 0.1 0.068 12.8 0.1 4.0 4 0 0 4 4 3 0 zinc-ribbon domain zinc_ribbon_5 PF13719.1 CBZ55158.1 - 0.11 12.1 0.1 0.11 12.1 0.1 4.0 4 0 0 4 4 3 0 zinc-ribbon domain Ribosomal_S27e PF01667.12 CBZ55158.1 - 0.22 11.0 4.0 2.1 7.9 0.9 2.4 2 0 0 2 2 2 0 Ribosomal protein S27 DUF3716 PF12511.3 CBZ55158.1 - 2.4 7.8 12.7 0.072 12.7 4.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3716) DRP PF06044.7 CBZ55158.1 - 3.2 6.6 7.0 2 7.3 0.1 2.0 2 0 0 2 2 2 0 Dam-replacing family HypA PF01155.14 CBZ55158.1 - 4.4 7.0 12.5 0.034 13.8 2.4 2.0 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family Terminase_GpA PF05876.7 CBZ55158.1 - 6.3 5.0 10.0 0.18 10.1 2.9 1.4 2 0 0 2 2 2 0 Phage terminase large subunit (GpA) PADR1 PF08063.7 CBZ55158.1 - 8.6 5.8 12.0 1.4 8.3 0.5 2.6 2 1 0 2 2 2 0 PADR1 (NUC008) domain WD40 PF00400.27 CBZ55159.1 - 0.043 13.7 14.9 0.17 11.8 0.0 4.1 4 1 0 4 4 4 0 WD domain, G-beta repeat XkdN PF08890.6 CBZ55160.1 - 0.16 11.7 0.5 2.8 7.7 0.0 2.2 2 0 0 2 2 2 0 Phage XkdN-like protein HA2 PF04408.18 CBZ55161.1 - 1.8e-29 101.7 0.0 4.4e-29 100.5 0.0 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 CBZ55161.1 - 8.2e-28 96.5 0.0 2.6e-27 94.9 0.0 1.9 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 CBZ55161.1 - 7.7e-10 38.5 0.0 2e-09 37.1 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 CBZ55161.1 - 6.4e-07 29.5 0.0 1.9e-06 28.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain S1 PF00575.18 CBZ55161.1 - 1e-05 25.5 0.2 2.4e-05 24.3 0.1 1.7 1 0 0 1 1 1 1 S1 RNA binding domain DEAD PF00270.24 CBZ55161.1 - 0.00021 20.8 0.1 0.00057 19.4 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase T2SE PF00437.15 CBZ55161.1 - 0.0008 18.3 0.1 0.0022 16.9 0.0 1.7 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_19 PF13245.1 CBZ55161.1 - 0.0015 18.2 0.3 0.006 16.3 0.1 2.1 2 0 0 2 2 2 1 Part of AAA domain ABC_tran PF00005.22 CBZ55161.1 - 0.012 15.9 0.9 0.99 9.7 0.2 3.3 2 1 0 3 3 3 0 ABC transporter AAA_25 PF13481.1 CBZ55161.1 - 0.043 13.2 0.0 0.13 11.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 CBZ55161.1 - 0.045 13.1 0.1 2 7.7 0.0 2.6 2 0 0 2 2 2 0 AAA-like domain PhoH PF02562.11 CBZ55161.1 - 0.075 12.2 0.0 0.2 10.8 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein AAA PF00004.24 CBZ55161.1 - 0.092 12.9 0.7 1.6 8.9 0.1 3.1 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 CBZ55161.1 - 0.098 12.5 0.0 0.53 10.1 0.0 2.2 1 1 0 1 1 1 0 AAA domain Myosin_head PF00063.16 CBZ55161.1 - 0.25 9.3 0.0 0.4 8.6 0.0 1.2 1 0 0 1 1 1 0 Myosin head (motor domain) Sec7 PF01369.15 CBZ55162.1 - 4.4e-44 150.4 0.0 6.7e-44 149.8 0.0 1.2 1 0 0 1 1 1 1 Sec7 domain RabGAP-TBC PF00566.13 CBZ55162.1 - 4.7e-28 98.1 0.0 1.1e-27 96.9 0.0 1.6 1 0 0 1 1 1 1 Rab-GTPase-TBC domain BROMI PF14961.1 CBZ55162.1 - 1.6 5.7 0.6 2.2 5.2 0.4 1.0 1 0 0 1 1 1 0 Broad-minded protein AAA PF00004.24 CBZ55163.1 - 1.4e-36 125.6 0.0 3.6e-36 124.2 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 CBZ55163.1 - 3.2e-06 26.3 0.0 6.7e-06 25.3 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_25 PF13481.1 CBZ55163.1 - 4.1e-06 26.3 1.3 0.0021 17.4 0.2 2.4 1 1 1 2 2 2 2 AAA domain AAA_22 PF13401.1 CBZ55163.1 - 5e-06 26.6 0.2 0.00015 21.8 0.2 2.5 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 CBZ55163.1 - 0.00017 21.3 0.0 0.0006 19.5 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 CBZ55163.1 - 0.00046 20.1 0.0 0.0012 18.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 CBZ55163.1 - 0.00068 19.6 5.0 0.0019 18.1 0.1 3.4 3 1 0 3 3 3 1 AAA ATPase domain AAA_33 PF13671.1 CBZ55163.1 - 0.00092 19.1 0.1 0.0029 17.4 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 CBZ55163.1 - 0.0012 19.6 0.0 0.004 17.9 0.0 1.8 1 1 0 1 1 1 1 AAA domain TIP49 PF06068.8 CBZ55163.1 - 0.0014 17.4 0.0 0.0022 16.7 0.0 1.2 1 0 0 1 1 1 1 TIP49 C-terminus AAA_14 PF13173.1 CBZ55163.1 - 0.0026 17.6 0.0 0.0076 16.1 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 CBZ55163.1 - 0.0041 16.8 0.1 0.017 14.8 0.1 2.1 1 0 0 1 1 1 1 Part of AAA domain AAA_18 PF13238.1 CBZ55163.1 - 0.0054 17.0 0.0 0.011 16.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain Sigma54_activ_2 PF14532.1 CBZ55163.1 - 0.0072 16.3 0.0 0.11 12.5 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain NACHT PF05729.7 CBZ55163.1 - 0.014 15.0 1.0 0.1 12.2 0.1 2.4 2 0 0 2 2 2 0 NACHT domain Mg_chelatase PF01078.16 CBZ55163.1 - 0.022 13.9 0.0 0.05 12.7 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_28 PF13521.1 CBZ55163.1 - 0.022 14.7 0.0 0.022 14.7 0.0 2.5 3 0 0 3 3 2 0 AAA domain AAA_24 PF13479.1 CBZ55163.1 - 0.026 14.1 0.1 0.052 13.1 0.1 1.4 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 CBZ55163.1 - 0.032 13.6 0.0 0.063 12.6 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein Zeta_toxin PF06414.7 CBZ55163.1 - 0.042 12.9 0.5 0.079 12.0 0.0 1.6 2 0 0 2 2 2 0 Zeta toxin RNA_helicase PF00910.17 CBZ55163.1 - 0.08 13.1 0.0 0.18 12.0 0.0 1.6 1 0 0 1 1 1 0 RNA helicase SKI PF01202.17 CBZ55163.1 - 0.13 12.1 3.0 0.16 11.8 0.0 2.5 3 0 0 3 3 2 0 Shikimate kinase AAA_10 PF12846.2 CBZ55163.1 - 0.13 11.6 0.3 0.53 9.6 0.1 2.0 2 0 0 2 2 2 0 AAA-like domain AAA_13 PF13166.1 CBZ55163.1 - 0.2 10.0 1.3 2.7 6.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain KaiC PF06745.8 CBZ55163.1 - 0.22 10.6 0.6 2.1 7.4 0.0 2.1 1 1 1 2 2 2 0 KaiC Rootletin PF15035.1 CBZ55163.1 - 5.1 7.0 9.4 0.87 9.5 1.8 2.2 1 1 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion UPF0029 PF01205.14 CBZ55166.1 - 1.3e-23 82.7 2.4 1.9e-22 78.9 1.6 2.2 1 1 0 1 1 1 1 Uncharacterized protein family UPF0029 RWD PF05773.17 CBZ55166.1 - 0.00074 19.3 0.0 0.0012 18.6 0.0 1.3 1 0 0 1 1 1 1 RWD domain DUF1387 PF07139.6 CBZ55166.1 - 0.16 11.5 0.1 0.16 11.5 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1387) AAA PF00004.24 CBZ55167.1 - 1.4e-06 28.5 0.0 0.0068 16.6 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) PseudoU_synth_2 PF00849.17 CBZ55168.1 - 2.3e-24 86.1 0.1 3.5e-23 82.2 0.1 2.4 1 1 0 1 1 1 1 RNA pseudouridylate synthase TPR_11 PF13414.1 CBZ55169.1 - 8.4e-14 50.9 2.1 1.2e-08 34.4 0.0 2.8 1 1 2 3 3 3 2 TPR repeat TPR_16 PF13432.1 CBZ55169.1 - 2.6e-10 40.6 1.0 1.1e-05 25.9 0.1 3.7 2 1 1 3 3 3 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 CBZ55169.1 - 1.2e-09 37.8 3.3 0.00017 21.4 1.5 2.8 3 0 0 3 3 3 2 Fis1 C-terminal tetratricopeptide repeat TPR_1 PF00515.23 CBZ55169.1 - 2.5e-07 30.0 0.9 0.2 11.3 0.6 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 CBZ55169.1 - 2.7e-07 30.8 0.4 1.1e-06 28.8 0.1 2.2 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.12 CBZ55169.1 - 1.3e-06 27.9 7.5 0.089 12.7 1.2 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.1 CBZ55169.1 - 2.8e-06 26.7 1.6 0.0019 17.8 1.2 3.9 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 CBZ55169.1 - 1.7e-05 24.6 8.1 0.022 14.6 0.7 3.4 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_14 PF13428.1 CBZ55169.1 - 0.00022 21.5 2.1 0.0025 18.2 1.5 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat Apc3 PF12895.2 CBZ55169.1 - 0.0058 16.7 2.5 0.017 15.2 1.7 1.8 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 CBZ55169.1 - 0.016 15.6 2.3 0.18 12.3 1.5 3.0 2 1 0 2 2 1 0 Tetratricopeptide repeat QCR10 PF09796.4 CBZ55169.1 - 0.064 12.9 0.0 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) AlkA_N PF06029.6 CBZ55169.1 - 0.066 13.2 0.2 0.13 12.3 0.2 1.4 1 0 0 1 1 1 0 AlkA N-terminal domain Rapsyn_N PF10579.4 CBZ55169.1 - 0.084 12.6 2.2 0.77 9.6 0.1 2.7 2 1 1 3 3 3 0 Rapsyn N-terminal myristoylation and linker region TPR_8 PF13181.1 CBZ55169.1 - 0.14 12.0 0.5 4.6 7.2 0.3 2.8 2 1 1 3 3 3 0 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.1 CBZ55169.1 - 0.63 10.2 4.3 3.7 7.7 1.4 2.5 1 1 2 3 3 3 0 Alkyl sulfatase dimerisation S1 PF00575.18 CBZ55171.1 - 0.061 13.4 0.2 0.096 12.7 0.1 1.3 1 0 0 1 1 1 0 S1 RNA binding domain Methyltransf_16 PF10294.4 CBZ55172.1 - 6.6e-10 38.7 0.0 0.00025 20.5 0.0 2.3 2 0 0 2 2 2 2 Putative methyltransferase Methyltransf_23 PF13489.1 CBZ55172.1 - 5.7e-05 22.8 0.0 0.00018 21.2 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 CBZ55172.1 - 0.00052 19.4 0.0 0.00099 18.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.2 CBZ55172.1 - 0.00053 20.5 0.0 0.0014 19.1 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Cons_hypoth95 PF03602.10 CBZ55172.1 - 0.0021 17.4 0.0 0.0036 16.7 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_26 PF13659.1 CBZ55172.1 - 0.0031 17.5 0.2 0.0059 16.6 0.1 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CBZ55172.1 - 0.054 13.9 0.0 0.21 12.0 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_31 PF13847.1 CBZ55172.1 - 0.15 11.6 0.0 0.32 10.5 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain DUF2183 PF09949.4 CBZ55173.1 - 0.004 17.0 0.0 0.0085 16.0 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) 60KD_IMP PF02096.15 CBZ55174.1 - 4.3e-09 36.3 0.1 6.8e-09 35.6 0.0 1.2 1 0 0 1 1 1 1 60Kd inner membrane protein TPR_12 PF13424.1 CBZ55175.1 - 9.8e-11 41.4 7.0 1.9e-05 24.4 0.1 4.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 CBZ55175.1 - 0.039 13.8 1.3 0.29 11.1 0.2 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.1 CBZ55175.1 - 1.2 9.0 7.3 0.41 10.5 0.2 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat zf-HIT PF04438.11 CBZ55175.1 - 1.3 8.7 3.8 2.8 7.6 2.6 1.5 1 0 0 1 1 1 0 HIT zinc finger UPRTase PF14681.1 CBZ55177.1 - 6.7e-79 263.8 0.0 9.1e-79 263.4 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.22 CBZ55177.1 - 0.0017 18.0 0.0 0.0029 17.3 0.0 1.5 1 0 0 1 1 1 1 Phosphoribosyl transferase domain MIP-T3 PF10243.4 CBZ55178.1 - 8.3e-05 21.2 22.4 9.5e-05 21.0 15.5 1.1 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 DUF3639 PF12341.3 CBZ55179.1 - 2.4e-07 30.6 1.9 1.1e-06 28.4 0.0 2.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3639) MMS1_N PF10433.4 CBZ55179.1 - 0.36 8.9 0.0 0.55 8.3 0.0 1.2 1 0 0 1 1 1 0 Mono-functional DNA-alkylating methyl methanesulfonate N-term Ku_PK_bind PF08785.6 CBZ55180.1 - 2.2e-16 59.8 0.0 2.8e-09 36.8 0.0 2.7 2 0 0 2 2 2 2 Ku C terminal domain like Ku PF02735.11 CBZ55180.1 - 4.5e-13 49.0 0.1 1.3e-12 47.5 0.0 1.8 2 0 0 2 2 2 1 Ku70/Ku80 beta-barrel domain VWA_2 PF13519.1 CBZ55180.1 - 0.00014 21.9 0.0 0.021 14.9 0.0 2.3 2 0 0 2 2 2 1 von Willebrand factor type A domain Ku_N PF03731.10 CBZ55180.1 - 0.051 13.0 0.0 0.15 11.4 0.0 1.7 1 1 0 1 1 1 0 Ku70/Ku80 N-terminal alpha/beta domain Orbi_VP5 PF00901.12 CBZ55180.1 - 3.6 5.6 7.0 5.5 5.0 4.9 1.1 1 0 0 1 1 1 0 Orbivirus outer capsid protein VP5 Ku_C PF03730.9 CBZ55180.1 - 3.9 8.0 6.9 2.6 8.6 0.1 3.1 2 1 0 2 2 2 0 Ku70/Ku80 C-terminal arm IPPT PF01715.12 CBZ55181.1 - 1.2e-47 162.0 0.0 1.7e-47 161.5 0.0 1.1 1 0 0 1 1 1 1 IPP transferase zf-C2H2_jaz PF12171.3 CBZ55181.1 - 3.1e-05 23.9 2.5 8.5e-05 22.5 1.7 1.8 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 CBZ55181.1 - 0.00024 21.2 2.5 0.00065 19.8 1.7 1.8 1 0 0 1 1 1 1 Zinc-finger of C2H2 type DRY_EERY PF09750.4 CBZ55181.1 - 0.092 12.8 0.1 0.4 10.7 0.0 2.1 3 0 0 3 3 3 0 Alternative splicing regulator zf-C2H2_2 PF12756.2 CBZ55181.1 - 0.093 12.8 0.1 0.19 11.8 0.1 1.4 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) COX7a PF02238.10 CBZ55181.1 - 0.18 11.5 0.1 0.44 10.2 0.1 1.6 1 0 0 1 1 1 0 Cytochrome c oxidase subunit VIIa RRM_1 PF00076.17 CBZ55182.1 - 1.2e-38 130.5 0.0 1.3e-16 59.9 0.0 3.6 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBZ55182.1 - 4.3e-30 103.3 0.0 6.6e-09 35.4 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBZ55182.1 - 3e-27 94.3 0.0 9e-12 44.8 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.1 CBZ55182.1 - 0.0016 18.7 0.1 0.0016 18.7 0.1 2.5 2 0 0 2 2 2 1 linker between RRM2 and RRM3 domains in RBM39 protein RRM_3 PF08777.6 CBZ55182.1 - 0.0047 16.7 1.5 1.4 8.7 0.0 3.3 3 0 0 3 3 3 2 RNA binding motif IF4E PF01652.13 CBZ55183.1 - 4.5e-11 42.5 0.0 7.5e-11 41.8 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Pkinase PF00069.20 CBZ55184.1 - 1.3e-58 198.1 0.0 2.4e-34 118.6 0.0 3.1 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ55184.1 - 4.9e-23 81.5 0.0 1.6e-21 76.5 0.0 2.4 2 1 0 2 2 2 1 Protein tyrosine kinase Mtr2 PF10429.4 CBZ55184.1 - 0.33 10.6 0.5 3 7.5 0.1 2.5 2 0 0 2 2 2 0 Nuclear pore RNA shuttling protein Mtr2 DUF605 PF04652.11 CBZ55185.1 - 0.09 12.1 0.1 0.09 12.1 0.0 2.1 3 0 0 3 3 3 0 Vta1 like CLASP_N PF12348.3 CBZ55186.1 - 1.3e-15 57.3 0.2 2.1e-15 56.7 0.1 1.2 1 0 0 1 1 1 1 CLASP N terminal HEAT_2 PF13646.1 CBZ55186.1 - 0.021 15.0 0.6 1.3 9.3 0.1 3.1 3 0 0 3 3 3 0 HEAT repeats Viral_env_E26 PF11050.3 CBZ55186.1 - 0.34 10.0 0.1 0.6 9.2 0.0 1.3 1 0 0 1 1 1 0 Virus envelope protein E26 Adaptin_N PF01602.15 CBZ55186.1 - 0.38 9.0 0.0 3.1 5.9 0.0 1.8 1 1 0 1 1 1 0 Adaptin N terminal region HSP20 PF00011.16 CBZ55187.1 - 1.2e-21 76.4 0.2 1.7e-21 75.9 0.1 1.2 1 0 0 1 1 1 1 Hsp20/alpha crystallin family BON PF04972.12 CBZ55187.1 - 0.11 12.2 0.0 0.22 11.2 0.0 1.5 1 0 0 1 1 1 0 BON domain TRAUB PF08164.7 CBZ55188.1 - 1.7e-15 56.8 0.0 1.7e-15 56.8 0.0 2.4 3 0 0 3 3 3 1 Apoptosis-antagonizing transcription factor, C-terminal AATF-Che1 PF13339.1 CBZ55188.1 - 3.5e-07 30.4 0.0 3.5e-07 30.4 0.0 2.5 3 0 0 3 3 3 1 Apoptosis antagonizing transcription factor Mg_trans_NIPA PF05653.9 CBZ55189.1 - 3e-18 65.8 8.6 1.1e-09 37.6 0.7 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA Arm PF00514.18 CBZ55190.1 - 3.9e-05 23.2 6.7 0.29 11.0 0.0 8.1 9 0 0 9 9 9 2 Armadillo/beta-catenin-like repeat PUB PF09409.5 CBZ55191.1 - 4.5e-05 23.1 0.0 0.0001 21.9 0.0 1.6 1 0 0 1 1 1 1 PUB domain Daxx PF03344.10 CBZ55192.1 - 0.0017 16.9 37.1 0.0017 16.9 25.7 3.0 3 0 0 3 3 3 1 Daxx Family TH1 PF04858.8 CBZ55192.1 - 0.035 12.2 0.0 0.035 12.2 0.0 3.5 4 0 0 4 4 4 0 TH1 protein OmpH PF03938.9 CBZ55192.1 - 3.2 7.6 19.7 0.35 10.7 4.0 2.9 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Abhydrolase_6 PF12697.2 CBZ55193.1 - 2.3e-19 70.1 5.2 4e-19 69.3 3.6 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CBZ55193.1 - 1.8e-09 37.5 1.1 7.9e-09 35.4 0.8 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CBZ55193.1 - 8.1e-06 25.5 0.8 0.0019 17.7 0.2 2.6 2 1 0 2 2 2 1 alpha/beta hydrolase fold Esterase PF00756.15 CBZ55193.1 - 0.028 13.8 0.0 0.046 13.1 0.0 1.3 1 0 0 1 1 1 0 Putative esterase MRP-L27 PF09809.4 CBZ55195.1 - 2e-11 43.5 0.0 2.5e-11 43.1 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L27 AA_permease_2 PF13520.1 CBZ55196.1 - 0.05 12.1 0.2 0.05 12.1 0.1 1.4 2 0 0 2 2 2 0 Amino acid permease Abhydrolase_5 PF12695.2 CBZ55197.1 - 3.2e-07 30.2 0.2 8.8e-07 28.7 0.1 1.8 1 0 0 1 1 1 1 Alpha/beta hydrolase family CDC27 PF09507.5 CBZ55198.1 - 0.0011 18.3 28.6 0.089 11.9 0.3 2.4 2 0 0 2 2 2 2 DNA polymerase subunit Cdc27 XRCC4 PF06632.7 CBZ55199.1 - 0.0012 17.7 0.2 0.0039 16.1 0.2 1.8 1 0 0 1 1 1 1 DNA double-strand break repair and V(D)J recombination protein XRCC4 PA PF02225.17 CBZ55201.1 - 1.5e-07 31.0 0.0 2.6e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 PA domain MobB PF03205.9 CBZ55203.1 - 3.2e-06 26.8 0.0 9.5e-06 25.3 0.0 1.8 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B Corona_3 PF04694.7 CBZ55203.1 - 0.7 9.8 0.1 1.5 8.7 0.1 1.4 1 0 0 1 1 1 0 Coronavirus ORF3 protein Pox_A32 PF04665.7 CBZ55203.1 - 4.4 6.5 0.0 6.9 5.8 0.0 1.2 1 0 0 1 1 1 0 Poxvirus A32 protein Cys_Met_Meta_PP PF01053.15 CBZ55204.1 - 5e-116 387.1 0.0 5.6e-116 387.0 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 CBZ55204.1 - 1.7e-08 33.8 0.1 2.4e-08 33.3 0.1 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 CBZ55204.1 - 1e-07 31.0 0.0 1.2e-06 27.5 0.0 2.0 2 0 0 2 2 2 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 CBZ55204.1 - 5.4e-06 25.6 0.0 2e-05 23.8 0.0 1.7 1 1 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.16 CBZ55204.1 - 0.00013 21.2 0.0 0.00034 19.8 0.0 1.6 1 1 0 1 1 1 1 Beta-eliminating lyase SLA_LP_auto_ag PF05889.8 CBZ55204.1 - 0.0057 15.1 0.0 0.0079 14.7 0.0 1.1 1 0 0 1 1 1 1 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) Nop16 PF09420.5 CBZ55207.1 - 2.4e-11 44.0 0.0 2.4e-11 44.0 0.0 2.3 2 1 0 2 2 2 1 Ribosome biogenesis protein Nop16 Spore_III_AF PF09581.5 CBZ55207.1 - 0.0097 15.7 2.9 0.015 15.1 2.0 1.3 1 0 0 1 1 1 1 Stage III sporulation protein AF (Spore_III_AF) DNA_pol3_a_NII PF11490.3 CBZ55207.1 - 7.3 6.2 9.1 1.4 8.5 2.6 2.2 1 1 1 2 2 2 0 DNA polymerase III polC-type N-terminus II Mito_fiss_reg PF05308.6 CBZ55208.1 - 6.3 6.0 9.8 1.7 7.9 1.1 2.5 2 0 0 2 2 2 0 Mitochondrial fission regulator Trichoplein PF13868.1 CBZ55209.1 - 5.5e-50 169.7 148.1 5.5e-50 169.7 102.6 2.0 1 1 1 2 2 2 1 Tumour suppressor, Mitostatin DEAD PF00270.24 CBZ55210.1 - 4.7e-43 146.5 0.1 9e-43 145.6 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF4217 PF13959.1 CBZ55210.1 - 1.2e-21 76.0 0.4 2.2e-21 75.1 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.26 CBZ55210.1 - 4.3e-21 74.5 0.0 1.9e-20 72.4 0.0 2.2 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.10 CBZ55210.1 - 0.034 13.9 0.0 0.097 12.4 0.0 1.8 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit eIF2_C PF09173.6 CBZ55210.1 - 0.099 12.6 0.8 0.58 10.2 0.0 2.5 3 0 0 3 3 3 0 Initiation factor eIF2 gamma, C terminal Neugrin PF06413.6 CBZ55210.1 - 0.13 12.0 1.7 0.28 10.9 1.2 1.5 1 0 0 1 1 1 0 Neugrin DEAD PF00270.24 CBZ55212.1 - 3.1e-40 137.4 0.0 4.2e-40 136.9 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CBZ55212.1 - 1.8e-26 91.8 0.1 3.3e-26 90.9 0.1 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain CMS1 PF14617.1 CBZ55212.1 - 0.054 12.5 0.0 0.11 11.5 0.0 1.4 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit ResIII PF04851.10 CBZ55212.1 - 0.094 12.5 0.0 1.5 8.5 0.0 2.1 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Sulfate_transp PF00916.15 CBZ55213.1 - 2.6e-52 177.5 5.9 1.4e-51 175.1 4.1 2.0 1 1 0 1 1 1 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 CBZ55213.1 - 2.2e-22 78.5 2.2 2.2e-22 78.5 1.5 2.7 2 0 0 2 2 2 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 CBZ55213.1 - 1.3e-19 69.6 0.0 2.4e-19 68.8 0.0 1.4 1 0 0 1 1 1 1 STAS domain Scs3p PF10261.4 CBZ55214.1 - 4.3e-07 29.2 0.0 8.3e-07 28.2 0.0 1.4 1 0 0 1 1 1 1 Inositol phospholipid synthesis and fat-storage-inducing TM DUF2413 PF10310.4 CBZ55214.1 - 1.8 7.3 3.6 3.6 6.3 2.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) adh_short PF00106.20 CBZ55216.1 - 2.9e-20 72.8 0.0 4.4e-20 72.2 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CBZ55216.1 - 8.2e-11 42.1 0.0 1.1e-10 41.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CBZ55216.1 - 2.8e-08 33.6 0.0 4.2e-08 33.0 0.0 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 CBZ55216.1 - 0.072 13.0 0.0 0.41 10.6 0.0 2.2 1 1 0 1 1 1 0 NADH(P)-binding Epimerase PF01370.16 CBZ55216.1 - 0.18 11.2 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family IF-2B PF01008.12 CBZ55217.1 - 3.1e-47 160.9 0.0 1.9e-37 128.7 0.0 2.1 2 0 0 2 2 2 2 Initiation factor 2 subunit family Nucleoporin_FG PF13634.1 CBZ55218.1 - 6.4 7.0 14.8 5.5 7.2 9.2 1.7 1 1 0 1 1 1 0 Nucleoporin FG repeat region Filament PF00038.16 CBZ55219.1 - 0.035 13.5 26.7 0.3 10.5 17.8 2.0 1 1 0 1 1 1 0 Intermediate filament protein ADIP PF11559.3 CBZ55219.1 - 0.35 10.7 25.3 1.5 8.6 6.2 2.4 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding HALZ PF02183.13 CBZ55219.1 - 0.5 10.1 9.0 0.79 9.4 0.1 3.2 3 0 0 3 3 3 0 Homeobox associated leucine zipper Peptidase_S64 PF08192.6 CBZ55219.1 - 1.1 7.4 7.5 1.3 7.2 5.2 1.1 1 0 0 1 1 1 0 Peptidase family S64 DUF812 PF05667.6 CBZ55219.1 - 2 6.8 20.9 3 6.2 14.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF812) HlyD PF00529.15 CBZ55219.1 - 3 7.0 30.1 4.4 6.5 20.9 1.2 1 0 0 1 1 1 0 HlyD family secretion protein UPF0242 PF06785.6 CBZ55219.1 - 3.8 6.0 12.3 5.7 5.5 8.5 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) Exonuc_VII_L PF02601.10 CBZ55219.1 - 5.1 6.1 17.3 7.4 5.6 12.0 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Tropomyosin_1 PF12718.2 CBZ55219.1 - 8.6 6.1 35.6 2.7 7.8 6.3 2.2 1 1 1 2 2 2 0 Tropomyosin like SRP54 PF00448.17 CBZ55220.1 - 1e-79 266.5 0.1 2.1e-79 265.5 0.1 1.6 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.14 CBZ55220.1 - 1.5e-27 95.8 1.8 1.5e-27 95.8 1.3 3.1 3 1 0 3 3 1 1 Signal peptide binding domain CbiA PF01656.18 CBZ55220.1 - 4.7e-09 35.9 0.1 6.7e-08 32.1 0.0 2.4 2 1 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain SRP54_N PF02881.14 CBZ55220.1 - 1e-08 35.1 0.1 1.7e-07 31.2 0.0 2.9 3 0 0 3 3 3 1 SRP54-type protein, helical bundle domain AAA_33 PF13671.1 CBZ55220.1 - 1e-07 31.9 0.2 3e-07 30.4 0.0 1.8 2 0 0 2 2 2 1 AAA domain MobB PF03205.9 CBZ55220.1 - 9.3e-07 28.6 0.0 2.5e-06 27.2 0.0 1.7 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B cobW PF02492.14 CBZ55220.1 - 1.2e-06 28.1 0.1 4.1e-06 26.3 0.1 1.9 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain ArgK PF03308.11 CBZ55220.1 - 4.8e-05 22.2 0.2 0.002 16.9 0.0 2.9 2 1 0 2 2 2 1 ArgK protein AAA_31 PF13614.1 CBZ55220.1 - 6e-05 23.0 0.7 0.35 10.7 0.0 3.5 3 2 1 4 4 4 2 AAA domain Zeta_toxin PF06414.7 CBZ55220.1 - 0.00042 19.4 0.0 0.0011 18.0 0.0 1.7 1 0 0 1 1 1 1 Zeta toxin AAA_17 PF13207.1 CBZ55220.1 - 0.00052 20.8 0.0 0.00095 19.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 CBZ55220.1 - 0.0017 18.3 0.0 0.0038 17.2 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_30 PF13604.1 CBZ55220.1 - 0.0021 17.6 0.0 0.0056 16.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 CBZ55220.1 - 0.0026 17.9 0.1 0.012 15.7 0.0 2.2 2 0 0 2 2 1 1 AAA domain APS_kinase PF01583.15 CBZ55220.1 - 0.0038 16.9 0.0 0.0083 15.7 0.0 1.5 1 0 0 1 1 1 1 Adenylylsulphate kinase SRPRB PF09439.5 CBZ55220.1 - 0.0048 16.1 0.8 4.9 6.3 0.0 3.1 3 0 0 3 3 3 1 Signal recognition particle receptor beta subunit AAA_18 PF13238.1 CBZ55220.1 - 0.012 15.8 0.0 0.057 13.7 0.0 2.2 1 1 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.12 CBZ55220.1 - 0.013 15.0 0.0 0.045 13.2 0.0 1.9 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein DUF2209 PF09974.4 CBZ55220.1 - 0.017 15.1 1.3 0.029 14.4 0.2 2.0 2 0 0 2 2 1 0 Uncharacterized protein conserved in archaea (DUF2209) AAA_28 PF13521.1 CBZ55220.1 - 0.037 13.9 0.0 0.07 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain Thymidylate_kin PF02223.12 CBZ55220.1 - 0.053 12.8 0.0 0.15 11.4 0.0 1.8 1 0 0 1 1 1 0 Thymidylate kinase VirC1 PF07015.6 CBZ55220.1 - 0.056 12.5 0.0 0.11 11.5 0.0 1.5 1 0 0 1 1 1 0 VirC1 protein KTI12 PF08433.5 CBZ55220.1 - 0.082 12.0 0.0 0.21 10.7 0.0 1.6 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_25 PF13481.1 CBZ55220.1 - 0.088 12.1 0.0 0.25 10.7 0.0 1.8 1 1 0 1 1 1 0 AAA domain PduV-EutP PF10662.4 CBZ55220.1 - 0.093 12.2 1.4 4.1 6.9 0.0 2.8 3 0 0 3 3 2 0 Ethanolamine utilisation - propanediol utilisation ArsA_ATPase PF02374.10 CBZ55220.1 - 0.14 11.1 4.5 0.32 9.9 0.1 3.1 2 1 0 2 2 2 0 Anion-transporting ATPase Glyco_trans_4_2 PF13477.1 CBZ55220.1 - 0.15 11.8 0.0 0.28 10.9 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase 4-like ResIII PF04851.10 CBZ55220.1 - 0.16 11.8 0.8 0.82 9.4 0.6 2.1 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit RNA_pol_A_bac PF01000.21 CBZ55222.1 - 2.6e-09 37.2 0.0 5.3e-09 36.2 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 CBZ55222.1 - 0.00031 19.7 0.0 0.00059 18.9 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain HHH_5 PF14520.1 CBZ55222.1 - 0.00042 20.4 0.0 0.00098 19.2 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix domain RNA_pol_A_CTD PF03118.10 CBZ55222.1 - 0.039 13.3 0.0 0.074 12.4 0.0 1.3 1 0 0 1 1 1 0 Bacterial RNA polymerase, alpha chain C terminal domain SR-25 PF10500.4 CBZ55222.1 - 1.5 8.2 15.8 0.088 12.2 1.4 2.6 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Nop14 PF04147.7 CBZ55223.1 - 2e-44 151.8 153.1 4.7e-27 94.3 82.8 4.8 3 1 1 4 4 4 4 Nop14-like family Iso_dh PF00180.15 CBZ55224.1 - 2.2e-71 240.6 0.0 2.7e-71 240.3 0.0 1.1 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase DUF89 PF01937.14 CBZ55225.1 - 3.2e-69 233.4 0.1 4.1e-69 233.0 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function DUF89 DUF1155 PF06633.6 CBZ55225.1 - 0.025 13.8 0.0 0.054 12.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1155) Cmc1 PF08583.5 CBZ55226.1 - 0.016 14.9 0.2 0.031 14.0 0.1 1.5 1 0 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like MAR_sialic_bdg PF10564.4 CBZ55226.1 - 0.075 12.8 0.1 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Sialic-acid binding micronemal adhesive repeat Pkinase PF00069.20 CBZ55227.1 - 3e-53 180.6 0.1 5.2e-53 179.8 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ55227.1 - 3.9e-25 88.3 0.1 1.6e-24 86.4 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase RIO1 PF01163.17 CBZ55227.1 - 0.00023 20.5 0.0 0.00092 18.6 0.0 2.0 1 1 0 1 1 1 1 RIO1 family Pox_ser-thr_kin PF05445.6 CBZ55227.1 - 0.096 11.4 0.0 0.17 10.6 0.0 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Ras PF00071.17 CBZ55228.1 - 1.7e-57 193.3 0.4 2e-57 193.1 0.3 1.0 1 0 0 1 1 1 1 Ras family Arf PF00025.16 CBZ55228.1 - 4.4e-21 74.8 0.1 5.7e-21 74.5 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Miro PF08477.8 CBZ55228.1 - 5.1e-18 65.6 0.0 7e-18 65.2 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Gtr1_RagA PF04670.7 CBZ55228.1 - 6.1e-10 38.6 0.1 7.8e-10 38.2 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 CBZ55228.1 - 9.7e-06 25.1 0.0 1.6e-05 24.3 0.0 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 CBZ55228.1 - 2e-05 24.4 0.0 0.00011 22.0 0.0 1.9 1 1 1 2 2 2 1 50S ribosome-binding GTPase SRPRB PF09439.5 CBZ55228.1 - 0.00036 19.7 0.1 0.00098 18.3 0.0 1.6 1 1 0 2 2 2 1 Signal recognition particle receptor beta subunit AAA_16 PF13191.1 CBZ55228.1 - 0.0013 18.7 0.0 0.039 13.9 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_5 PF07728.9 CBZ55228.1 - 0.0092 15.7 0.0 0.07 12.8 0.0 2.0 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_29 PF13555.1 CBZ55228.1 - 0.016 14.7 0.9 0.038 13.5 0.1 2.0 3 0 0 3 3 3 0 P-loop containing region of AAA domain DUF258 PF03193.11 CBZ55228.1 - 0.016 14.4 0.4 0.053 12.7 0.1 1.9 2 1 0 2 2 2 0 Protein of unknown function, DUF258 AAA_15 PF13175.1 CBZ55228.1 - 0.031 13.3 0.0 0.038 13.0 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.1 CBZ55228.1 - 0.065 13.3 0.0 0.14 12.2 0.0 1.8 1 1 0 1 1 1 0 AAA domain FeoB_N PF02421.13 CBZ55228.1 - 0.12 11.6 0.0 0.98 8.6 0.0 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B ABC_tran PF00005.22 CBZ55228.1 - 0.13 12.5 0.2 0.36 11.1 0.1 1.9 1 1 0 1 1 1 0 ABC transporter F-box-like_2 PF13013.1 CBZ55229.1 - 3.2e-12 46.1 0.2 3.2e-12 46.1 0.1 2.1 3 0 0 3 3 3 1 F-box-like domain LRR_4 PF12799.2 CBZ55229.1 - 1.8e-07 30.6 0.1 0.0032 17.0 0.0 4.0 2 1 2 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CBZ55229.1 - 8.9e-07 28.5 7.0 0.0012 18.5 0.1 3.8 2 1 2 4 4 4 4 Leucine rich repeat LRR_6 PF13516.1 CBZ55229.1 - 0.012 15.6 2.3 15 6.0 0.0 5.0 6 1 1 7 7 7 0 Leucine Rich repeat Mob1_phocein PF03637.12 CBZ55230.1 - 6.8e-21 74.7 3.7 1.8e-13 50.5 2.2 3.2 3 0 0 3 3 3 3 Mob1/phocein family EIF_2_alpha PF07541.7 CBZ55231.1 - 7.5e-36 122.3 0.2 1.4e-35 121.4 0.0 1.5 2 0 0 2 2 2 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.18 CBZ55231.1 - 4.8e-11 42.5 0.2 1.3e-10 41.1 0.2 1.8 1 0 0 1 1 1 1 S1 RNA binding domain FSIP1 PF15554.1 CBZ55231.1 - 0.00067 18.5 3.1 0.0011 17.9 2.1 1.3 1 0 0 1 1 1 1 FSIP1 family EXOSC1 PF10447.4 CBZ55231.1 - 0.058 13.3 0.0 0.15 11.9 0.0 1.8 1 1 0 1 1 1 0 Exosome component EXOSC1/CSL4 MOZART2 PF12926.2 CBZ55231.1 - 0.091 12.3 2.5 2.5 7.7 0.0 2.6 3 0 0 3 3 3 0 Mitotic-spindle organizing gamma-tubulin ring associated DEAD PF00270.24 CBZ55232.1 - 1.3e-39 135.4 0.0 7.1e-37 126.4 0.0 2.1 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.26 CBZ55232.1 - 9.3e-29 99.1 0.3 1.7e-28 98.2 0.2 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Helicase_C_2 PF13307.1 CBZ55232.1 - 0.0069 16.3 0.0 0.011 15.6 0.0 1.3 1 0 0 1 1 1 1 Helicase C-terminal domain DUF1253 PF06862.7 CBZ55232.1 - 0.0075 14.7 0.0 0.025 12.9 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1253) ResIII PF04851.10 CBZ55232.1 - 0.023 14.5 0.0 0.15 11.8 0.0 2.2 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit WD40 PF00400.27 CBZ55234.1 - 4.3e-49 162.7 27.8 5.8e-10 38.6 0.0 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat MORN PF02493.15 CBZ55235.1 - 2.1e-34 115.2 67.5 4.9e-07 29.0 4.3 11.0 12 0 0 12 12 12 7 MORN repeat SM-ATX PF14438.1 CBZ55235.1 - 0.71 9.8 3.6 19 5.2 0.0 4.4 5 1 1 6 6 6 0 Ataxin 2 SM domain TFIIIC_sub6 PF10419.4 CBZ55235.1 - 3 7.3 15.8 14 5.2 0.1 6.2 6 0 0 6 6 6 0 TFIIIC subunit YL1 PF05764.8 CBZ55236.1 - 9.1e-27 94.2 35.7 9.1e-27 94.2 24.7 3.2 2 1 0 2 2 2 1 YL1 nuclear protein YL1_C PF08265.6 CBZ55236.1 - 1.3e-13 50.2 0.1 2.5e-13 49.3 0.1 1.4 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain DnaJ-X PF14308.1 CBZ55237.1 - 2.2e-62 209.9 0.4 3.8e-62 209.1 0.3 1.4 1 0 0 1 1 1 1 X-domain of DnaJ-containing DnaJ PF00226.26 CBZ55237.1 - 7.9e-27 92.7 2.2 1.8e-26 91.6 1.5 1.7 1 0 0 1 1 1 1 DnaJ domain Pkinase PF00069.20 CBZ55238.1 - 8.7e-22 77.5 0.0 2.1e-21 76.2 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.1 CBZ55238.1 - 1.5e-17 63.5 0.0 2.1e-16 59.7 0.0 2.6 2 1 0 2 2 2 1 Kinase-like Pkinase_Tyr PF07714.12 CBZ55238.1 - 5e-11 42.1 0.0 2.2e-09 36.7 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Vip3A_N PF12495.3 CBZ55239.1 - 0.12 12.0 0.2 0.31 10.6 0.1 1.7 1 0 0 1 1 1 0 Vegetative insecticide protein 3A N terminal WD40 PF00400.27 CBZ55240.1 - 3.4e-05 23.5 1.7 0.67 9.9 0.0 4.6 5 0 0 5 5 5 2 WD domain, G-beta repeat RAM PF15320.1 CBZ55240.1 - 0.47 10.7 4.0 0.9 9.8 2.8 1.4 1 0 0 1 1 1 0 mRNA cap methylation, RNMT-activating mini protein LRR_6 PF13516.1 CBZ55242.1 - 5.5e-07 28.9 0.8 0.46 10.7 0.0 4.8 4 0 0 4 4 4 3 Leucine Rich repeat EF-hand_7 PF13499.1 CBZ55243.1 - 0.012 15.7 0.0 0.15 12.2 0.0 2.6 1 1 1 2 2 2 0 EF-hand domain pair Cauli_AT PF03233.8 CBZ55243.1 - 0.054 13.2 4.2 0.077 12.6 2.9 1.2 1 0 0 1 1 1 0 Aphid transmission protein Exonuc_VII_L PF02601.10 CBZ55243.1 - 0.21 10.7 5.6 0.3 10.2 3.9 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit TcdA_TcdB PF12919.2 CBZ55243.1 - 0.24 9.8 9.4 0.055 11.9 4.2 1.5 1 1 0 1 1 1 0 TcdA/TcdB catalytic glycosyltransferase domain OmpH PF03938.9 CBZ55243.1 - 0.25 11.2 19.6 0.39 10.6 13.6 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF883 PF05957.8 CBZ55243.1 - 0.37 11.2 7.5 0.35 11.2 1.3 2.4 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) DUF2529 PF10740.4 CBZ55243.1 - 0.37 10.1 6.6 0.12 11.8 2.7 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2529) Ycf1 PF05758.7 CBZ55243.1 - 6 4.4 9.9 7.5 4.1 6.8 1.0 1 0 0 1 1 1 0 Ycf1 Ribosomal_L6e PF01159.14 CBZ55244.1 - 1.6e-35 121.6 1.1 2.3e-35 121.1 0.8 1.2 1 0 0 1 1 1 1 Ribosomal protein L6e SMC_Nse1 PF07574.8 CBZ55244.1 - 0.083 12.5 0.3 0.11 12.0 0.2 1.2 1 0 0 1 1 1 0 Nse1 non-SMC component of SMC5-6 complex DnaJ PF00226.26 CBZ55245.1 - 4.6e-29 99.9 1.4 7.1e-29 99.3 1.0 1.3 1 0 0 1 1 1 1 DnaJ domain PC_rep PF01851.17 CBZ55246.1 - 5.1e-15 54.7 21.9 0.00087 19.3 0.2 9.7 10 0 0 10 10 10 5 Proteasome/cyclosome repeat HEAT PF02985.17 CBZ55246.1 - 0.0035 17.2 0.0 8.9 6.6 0.0 3.7 2 0 0 2 2 2 2 HEAT repeat AAA_33 PF13671.1 CBZ55247.1 - 1.3e-07 31.5 7.1 0.0012 18.7 0.0 3.8 4 0 0 4 4 4 2 AAA domain KTI12 PF08433.5 CBZ55247.1 - 3.3e-06 26.5 0.0 0.055 12.6 0.0 2.4 2 0 0 2 2 2 2 Chromatin associated protein KTI12 AAA_17 PF13207.1 CBZ55247.1 - 5.3e-05 24.0 0.1 0.001 19.8 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 CBZ55247.1 - 0.0004 20.6 1.1 0.0047 17.2 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.1 CBZ55247.1 - 0.0082 16.1 0.1 0.07 13.1 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 CBZ55247.1 - 0.021 14.9 0.0 0.17 12.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain 6PF2K PF01591.13 CBZ55247.1 - 0.094 11.7 0.0 0.17 10.9 0.0 1.4 1 0 0 1 1 1 0 6-phosphofructo-2-kinase DUF605 PF04652.11 CBZ55248.1 - 1.2 8.5 21.2 4.5 6.5 14.7 2.0 1 0 0 1 1 1 0 Vta1 like Clat_adaptor_s PF01217.15 CBZ55251.1 - 2.4e-42 144.0 0.1 2.6e-42 143.9 0.1 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain HhH-GPD PF00730.20 CBZ55252.1 - 1.7e-16 60.4 0.0 3.4e-16 59.4 0.0 1.5 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein NUDIX_4 PF14815.1 CBZ55252.1 - 6.5e-07 28.7 0.5 0.018 14.4 0.0 2.7 2 0 0 2 2 2 2 NUDIX domain HHH PF00633.18 CBZ55252.1 - 0.00071 19.1 0.1 0.0017 17.9 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif EndIII_4Fe-2S PF10576.4 CBZ55252.1 - 1.1 9.5 14.7 0.03 14.4 4.9 2.5 3 0 0 3 3 3 0 Iron-sulfur binding domain of endonuclease III Golgin_A5 PF09787.4 CBZ55252.1 - 9.6 4.5 11.1 22 3.3 7.7 1.7 1 0 0 1 1 1 0 Golgin subfamily A member 5 LMSTEN PF07988.7 CBZ55253.1 - 0.57 9.5 11.0 0.22 10.8 3.2 3.3 2 1 1 3 3 3 0 LMSTEN motif Hormone_1 PF00103.15 CBZ55254.1 - 1.4 8.2 0.1 4.7 6.5 0.1 1.8 2 0 0 2 2 2 0 Somatotropin hormone family DUF1242 PF06842.7 CBZ55256.1 - 1.7e-15 56.2 0.2 2.2e-15 55.8 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1242) DUF4118 PF13493.1 CBZ55256.1 - 0.089 13.0 0.1 0.098 12.8 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4118) DUF1049 PF06305.6 CBZ55257.1 - 0.23 10.9 0.0 0.45 10.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) Ribosomal_L22 PF00237.14 CBZ55258.1 - 2e-24 85.5 0.2 2.7e-24 85.1 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e Ribosomal_L7Ae PF01248.21 CBZ55259.1 - 1.6e-17 62.7 0.1 4.3e-17 61.4 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RCC1 PF00415.13 CBZ55260.1 - 3.6e-36 123.1 11.6 6.3e-13 48.7 0.2 7.3 7 0 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 CBZ55260.1 - 1.9e-31 106.9 24.1 5.6e-08 32.1 0.2 7.0 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat Kelch_2 PF07646.10 CBZ55260.1 - 0.11 12.3 0.0 0.44 10.3 0.0 2.0 1 0 0 1 1 1 0 Kelch motif Cyt-b5 PF00173.23 CBZ55261.1 - 1.7e-19 69.4 0.1 3.3e-19 68.4 0.0 1.5 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain FPL PF09758.4 CBZ55263.1 - 7.4e-50 168.5 3.6 9.9e-50 168.1 2.5 1.2 1 0 0 1 1 1 1 Uncharacterised conserved protein MMS19_C PF12460.3 CBZ55263.1 - 0.091 11.4 0.6 0.16 10.6 0.4 1.3 1 0 0 1 1 1 0 RNAPII transcription regulator C-terminal DDHD PF02862.12 CBZ55264.1 - 4.2e-24 85.6 12.0 1.5e-16 60.8 0.0 6.0 3 2 0 4 4 4 2 DDHD domain DUF676 PF05057.9 CBZ55264.1 - 0.084 12.1 0.1 0.19 10.9 0.0 1.5 2 0 0 2 2 2 0 Putative serine esterase (DUF676) Lipase_3 PF01764.20 CBZ55264.1 - 0.12 11.9 0.0 0.24 11.0 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) DUF3896 PF13035.1 CBZ55264.1 - 0.24 11.4 0.2 0.52 10.4 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3896) Mob1_phocein PF03637.12 CBZ55265.1 - 0.012 15.3 0.0 0.012 15.2 0.0 1.0 1 0 0 1 1 1 0 Mob1/phocein family Thiol_cytolysin PF01289.14 CBZ55265.1 - 0.064 11.6 0.3 0.067 11.5 0.2 1.0 1 0 0 1 1 1 0 Thiol-activated cytolysin Chorein_N PF12624.2 CBZ55266.1 - 3.4e-22 78.1 0.7 5.9e-22 77.4 0.5 1.4 1 0 0 1 1 1 1 N-terminal region of Chorein, a TM vesicle-mediated sorter DUF1162 PF06650.7 CBZ55266.1 - 7.6e-12 45.0 0.0 0.00011 21.5 0.0 2.7 3 0 0 3 3 3 2 Protein of unknown function (DUF1162) DUF2769 PF10967.3 CBZ55266.1 - 0.13 12.6 0.7 0.41 10.9 0.5 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2769) DUF605 PF04652.11 CBZ55269.1 - 6.4 6.0 13.6 9 5.5 9.4 1.2 1 0 0 1 1 1 0 Vta1 like zf-C2HC_2 PF13913.1 CBZ55270.1 - 6.6e-07 28.8 10.9 0.00054 19.5 0.7 3.5 3 0 0 3 3 3 2 zinc-finger of a C2HC-type zf-TRAF PF02176.13 CBZ55270.1 - 0.0019 18.5 3.8 0.0026 18.0 1.7 1.9 1 1 0 1 1 1 1 TRAF-type zinc finger Trm112p PF03966.11 CBZ55270.1 - 0.051 13.9 0.1 0.15 12.4 0.1 1.8 1 0 0 1 1 1 0 Trm112p-like protein zf-Di19 PF05605.7 CBZ55270.1 - 0.21 11.7 3.6 1.8 8.7 0.4 2.9 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding DUF2318 PF10080.4 CBZ55270.1 - 1 9.2 3.2 28 4.5 0.0 2.9 1 1 1 3 3 3 0 Predicted membrane protein (DUF2318) Adaptin_N PF01602.15 CBZ55271.1 - 1.8e-120 402.7 0.0 2.1e-120 402.5 0.0 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.15 CBZ55271.1 - 3.7e-16 59.4 0.0 7.2e-16 58.5 0.0 1.4 1 0 0 1 1 1 1 Adaptin C-terminal domain HEAT_2 PF13646.1 CBZ55271.1 - 2.1e-07 31.1 1.7 0.014 15.6 0.0 4.1 3 1 0 3 3 3 2 HEAT repeats Cnd1 PF12717.2 CBZ55271.1 - 0.0078 16.0 1.5 0.42 10.4 0.5 3.0 2 1 1 3 3 3 1 non-SMC mitotic condensation complex subunit 1 DUF202 PF02656.10 CBZ55272.1 - 0.7 10.1 11.6 0.43 10.8 0.1 3.7 3 1 0 3 3 3 0 Domain of unknown function (DUF202) Cation_efflux PF01545.16 CBZ55272.1 - 1.7 7.6 14.5 0.015 14.3 0.9 2.2 2 0 0 2 2 2 0 Cation efflux family Sel1 PF08238.7 CBZ55273.1 - 5.2e-17 61.8 31.0 2.4e-06 28.0 0.0 10.6 12 0 0 12 12 12 6 Sel1 repeat zf-CCCH PF00642.19 CBZ55276.1 - 0.0016 18.0 6.1 0.12 12.0 1.9 3.7 2 1 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Transglut_core3 PF13471.1 CBZ55279.1 - 0.93 9.3 11.2 1.9 8.2 0.3 3.7 3 0 0 3 3 3 0 Transglutaminase-like superfamily CEP44 PF15007.1 CBZ55281.1 - 9.8e-32 109.4 0.0 1.7e-31 108.6 0.0 1.4 1 0 0 1 1 1 1 Centrosomal spindle body, CEP44 MTBP_mid PF14919.1 CBZ55281.1 - 0.18 10.4 0.0 0.29 9.7 0.0 1.2 1 0 0 1 1 1 0 MDM2-binding Bromo_TP PF07524.8 CBZ55282.1 - 9.6e-05 22.0 0.0 0.00014 21.4 0.0 1.2 1 0 0 1 1 1 1 Bromodomain associated TAF8_C PF10406.4 CBZ55282.1 - 0.0057 16.6 3.2 0.014 15.4 2.2 1.6 1 0 0 1 1 1 1 Transcription factor TFIID complex subunit 8 C-term Hexapep PF00132.19 CBZ55283.1 - 3.8e-07 29.3 3.1 0.0029 17.0 0.0 3.4 2 1 1 3 3 3 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 CBZ55283.1 - 0.0015 18.0 3.7 0.013 15.0 3.3 2.1 2 1 1 3 3 3 2 Hexapeptide repeat of succinyl-transferase DUF663 PF04950.7 CBZ55284.1 - 2.8e-68 230.0 0.0 2.8e-68 230.0 0.0 2.2 3 0 0 3 3 1 1 Protein of unknown function (DUF663) AARP2CN PF08142.7 CBZ55284.1 - 3.4e-23 80.9 0.0 9.3e-23 79.5 0.0 1.8 1 0 0 1 1 1 1 AARP2CN (NUC121) domain GTP_EFTU PF00009.22 CBZ55284.1 - 4.7e-07 29.4 1.9 9.1e-06 25.2 0.0 3.1 2 1 1 3 3 3 1 Elongation factor Tu GTP binding domain AAA PF00004.24 CBZ55284.1 - 7.1e-06 26.2 0.0 1.7e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 CBZ55284.1 - 3e-05 23.6 0.1 9.5e-05 22.0 0.1 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_33 PF13671.1 CBZ55284.1 - 0.00014 21.7 1.8 0.0004 20.2 0.0 2.8 3 0 0 3 3 1 1 AAA domain AAA_16 PF13191.1 CBZ55284.1 - 0.00015 21.7 0.0 0.00015 21.7 0.0 2.7 3 0 0 3 3 2 1 AAA ATPase domain AAA_17 PF13207.1 CBZ55284.1 - 0.00016 22.4 0.0 0.00016 22.4 0.0 3.4 3 0 0 3 3 2 1 AAA domain AAA_22 PF13401.1 CBZ55284.1 - 0.00022 21.3 0.0 0.00053 20.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.1 CBZ55284.1 - 0.00035 20.5 0.3 0.01 15.7 0.0 2.8 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 CBZ55284.1 - 0.0008 19.0 0.0 0.0016 18.1 0.0 1.5 1 0 0 1 1 1 1 NACHT domain MMR_HSR1 PF01926.18 CBZ55284.1 - 0.00098 19.0 0.1 0.003 17.5 0.0 1.9 2 0 0 2 2 1 1 50S ribosome-binding GTPase MobB PF03205.9 CBZ55284.1 - 0.0017 18.0 0.0 0.0053 16.4 0.0 1.8 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.1 CBZ55284.1 - 0.0035 17.6 5.2 0.0049 17.1 0.0 3.6 3 0 0 3 3 3 1 AAA domain AAA_14 PF13173.1 CBZ55284.1 - 0.0041 17.0 0.0 0.012 15.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 CBZ55284.1 - 0.0047 16.6 0.0 0.011 15.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) cobW PF02492.14 CBZ55284.1 - 0.0048 16.3 0.0 0.0093 15.4 0.0 1.5 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain Viral_helicase1 PF01443.13 CBZ55284.1 - 0.0074 15.8 0.0 0.017 14.6 0.0 1.6 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase Miro PF08477.8 CBZ55284.1 - 0.0075 16.7 0.1 0.033 14.6 0.0 2.1 2 0 0 2 2 1 1 Miro-like protein RNA_helicase PF00910.17 CBZ55284.1 - 0.0097 16.0 0.0 0.021 14.9 0.0 1.6 1 0 0 1 1 1 1 RNA helicase AAA_25 PF13481.1 CBZ55284.1 - 0.013 14.8 0.0 0.044 13.1 0.0 1.9 1 0 0 1 1 1 0 AAA domain UPF0079 PF02367.12 CBZ55284.1 - 0.02 14.5 0.0 0.047 13.3 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 NTPase_1 PF03266.10 CBZ55284.1 - 0.021 14.5 0.1 0.021 14.5 0.1 1.9 2 0 0 2 2 2 0 NTPase KAP_NTPase PF07693.9 CBZ55284.1 - 0.028 13.4 0.0 0.09 11.7 0.0 1.8 1 0 0 1 1 1 0 KAP family P-loop domain AAA_11 PF13086.1 CBZ55284.1 - 0.035 13.6 0.0 0.035 13.6 0.0 4.7 5 1 0 5 5 4 0 AAA domain DUF258 PF03193.11 CBZ55284.1 - 0.035 13.2 0.0 0.07 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 ATP_bind_1 PF03029.12 CBZ55284.1 - 0.084 12.3 0.0 0.16 11.4 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein ABC_tran PF00005.22 CBZ55284.1 - 0.085 13.1 3.9 0.11 12.7 0.0 2.8 3 0 0 3 3 2 0 ABC transporter PduV-EutP PF10662.4 CBZ55284.1 - 0.096 12.1 0.0 0.76 9.2 0.0 2.3 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation SRP54 PF00448.17 CBZ55284.1 - 0.17 11.3 2.9 1.5 8.2 0.0 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain RCC1 PF00415.13 CBZ55285.1 - 5.7e-42 141.6 22.1 4.2e-09 36.4 0.1 9.7 9 0 0 9 9 9 9 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 CBZ55285.1 - 5.4e-26 89.5 29.6 2e-06 27.2 0.1 7.7 7 0 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat SPX PF03105.14 CBZ55286.1 - 1.7e-11 44.4 0.6 1.7e-11 44.4 0.4 3.3 2 1 0 2 2 2 1 SPX domain zf-C3HC4 PF00097.20 CBZ55286.1 - 2.2e-05 23.9 9.1 4.4e-05 23.0 6.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CBZ55286.1 - 0.00014 21.7 11.2 0.00034 20.5 7.8 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 CBZ55286.1 - 0.00046 19.9 10.9 0.0011 18.8 7.5 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 CBZ55286.1 - 0.0043 16.7 7.6 0.01 15.5 5.2 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 CBZ55286.1 - 0.18 11.4 12.3 0.38 10.4 8.6 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) polyprenyl_synt PF00348.12 CBZ55286.1 - 0.42 9.4 0.0 0.71 8.6 0.0 1.2 1 0 0 1 1 1 0 Polyprenyl synthetase zf-RING_6 PF14835.1 CBZ55286.1 - 4.5 7.1 8.4 9.8 6.0 5.8 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein DUF572 PF04502.8 CBZ55287.1 - 1.3e-45 156.0 0.6 1.6e-45 155.7 0.4 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF572) DUF866 PF05907.8 CBZ55287.1 - 0.00011 21.6 1.9 0.00019 20.9 1.3 1.3 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) TF_Zn_Ribbon PF08271.7 CBZ55287.1 - 0.0011 18.2 8.3 0.0022 17.2 0.4 2.5 2 0 0 2 2 2 2 TFIIB zinc-binding Cys_rich_KTR PF14205.1 CBZ55287.1 - 0.0078 15.6 0.3 0.019 14.4 0.2 1.7 1 0 0 1 1 1 1 Cysteine-rich KTR IQ PF00612.22 CBZ55288.1 - 2.9 7.7 24.3 0.073 12.7 1.9 3.8 3 0 0 3 3 3 0 IQ calmodulin-binding motif RRM_2 PF04059.7 CBZ55289.1 - 3.3e-31 107.1 0.6 6e-31 106.2 0.4 1.4 1 0 0 1 1 1 1 RNA recognition motif 2 CRT-like PF08627.5 CBZ55290.1 - 8.2e-11 41.9 0.2 1.5e-10 41.0 0.2 1.4 1 0 0 1 1 1 1 CRT-like EamA PF00892.15 CBZ55290.1 - 1.9e-05 24.6 5.2 1.9e-05 24.6 3.6 3.3 3 1 1 4 4 4 1 EamA-like transporter family DUF914 PF06027.7 CBZ55290.1 - 5.3e-05 22.2 2.7 5.3e-05 22.2 1.9 2.1 2 1 0 2 2 2 1 Eukaryotic protein of unknown function (DUF914) EmrE PF13536.1 CBZ55290.1 - 0.00014 22.0 5.3 0.00014 22.0 3.7 3.3 3 1 1 4 4 4 1 Multidrug resistance efflux transporter DUF4418 PF14387.1 CBZ55290.1 - 0.04 13.6 3.5 0.75 9.5 0.2 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4418) Nuc_sug_transp PF04142.10 CBZ55290.1 - 0.045 12.8 2.2 1.3 8.0 0.1 2.6 3 0 0 3 3 3 0 Nucleotide-sugar transporter Rhamno_transf PF11316.3 CBZ55290.1 - 0.14 11.3 0.0 0.28 10.3 0.0 1.4 1 0 0 1 1 1 0 Putative rhamnosyl transferase UAA PF08449.6 CBZ55290.1 - 0.37 9.6 9.9 0.024 13.5 3.1 1.7 2 0 0 2 2 2 0 UAA transporter family GMC_oxred_N PF00732.14 CBZ55292.1 - 3.1e-60 203.8 0.0 6.7e-60 202.7 0.0 1.6 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 CBZ55292.1 - 2.1e-27 96.1 0.0 3.8e-13 49.9 0.0 3.6 3 1 0 3 3 3 2 GMC oxidoreductase Ribosomal_L19 PF01245.15 CBZ55293.1 - 4.1e-14 52.3 0.2 1e-13 51.0 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein L19 PhyH PF05721.8 CBZ55294.1 - 2.3e-10 40.8 0.0 1.7e-09 38.0 0.0 2.2 2 0 0 2 2 2 1 Phytanoyl-CoA dioxygenase (PhyH) Ribosomal_60s PF00428.14 CBZ55294.1 - 0.14 12.5 3.5 0.28 11.6 1.4 2.2 2 0 0 2 2 2 0 60s Acidic ribosomal protein EMG1 PF03587.9 CBZ55295.1 - 3.2e-53 180.0 0.0 3.9e-53 179.7 0.0 1.0 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase SPOUT_MTase PF02590.12 CBZ55295.1 - 0.074 12.7 0.0 0.17 11.6 0.0 1.6 2 0 0 2 2 2 0 Predicted SPOUT methyltransferase CBF PF03914.12 CBZ55296.1 - 8.6e-14 51.3 6.6 1.3e-12 47.5 1.0 3.4 2 1 0 2 2 2 2 CBF/Mak21 family SelR PF01641.13 CBZ55297.1 - 1.7e-41 140.7 0.0 2.1e-41 140.5 0.0 1.1 1 0 0 1 1 1 1 SelR domain DZR PF12773.2 CBZ55297.1 - 0.012 15.4 2.4 0.097 12.5 2.0 2.1 1 1 1 2 2 2 0 Double zinc ribbon RRN7 PF11781.3 CBZ55297.1 - 0.065 12.7 0.2 4.1 7.0 0.0 2.3 2 0 0 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 Zn_Tnp_IS1595 PF12760.2 CBZ55297.1 - 0.34 10.7 2.3 4.5 7.1 0.1 2.4 2 0 0 2 2 2 0 Transposase zinc-ribbon domain DUF2296 PF10058.4 CBZ55297.1 - 0.66 9.7 2.5 2 8.2 0.1 2.2 2 0 0 2 2 2 0 Predicted integral membrane metal-binding protein (DUF2296) DUF3633 PF12315.3 CBZ55298.1 - 0.085 12.1 0.1 0.15 11.3 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3633) Cyto_heme_lyase PF01265.12 CBZ55300.1 - 5.4e-64 216.2 0.0 1.3e-63 215.0 0.0 1.7 1 1 0 1 1 1 1 Cytochrome c/c1 heme lyase RRM_5 PF13893.1 CBZ55301.1 - 1.1e-07 31.6 0.0 0.00017 21.3 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CBZ55301.1 - 0.00065 19.2 0.0 0.01 15.4 0.0 2.4 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBZ55301.1 - 0.0019 18.1 0.0 0.0059 16.5 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Cobalamin_bind PF01122.14 CBZ55304.1 - 0.1 11.2 0.2 0.12 11.0 0.1 1.0 1 0 0 1 1 1 0 Eukaryotic cobalamin-binding protein Aha1_N PF09229.6 CBZ55305.1 - 5.4e-19 68.3 0.1 1.4e-18 67.0 0.1 1.8 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal TPR_11 PF13414.1 CBZ55305.1 - 1.6e-09 37.2 5.4 2e-05 24.1 0.4 2.9 2 1 1 3 3 3 2 TPR repeat TPR_2 PF07719.12 CBZ55305.1 - 4.7e-07 29.2 4.3 0.038 13.9 0.0 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 CBZ55305.1 - 6e-05 23.5 3.7 6e-05 23.5 2.6 3.5 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_9 PF13371.1 CBZ55305.1 - 0.00019 21.2 0.6 0.00046 19.9 0.4 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_6 PF13174.1 CBZ55305.1 - 0.0079 16.5 0.8 0.51 10.9 0.0 3.7 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 CBZ55305.1 - 0.012 16.1 9.7 0.21 12.2 0.4 3.8 2 1 2 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.23 CBZ55305.1 - 0.032 13.8 7.5 0.88 9.2 0.0 4.0 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_19 PF14559.1 CBZ55305.1 - 0.032 14.5 5.0 0.041 14.2 1.2 2.6 1 1 1 2 2 2 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 CBZ55305.1 - 0.067 13.0 0.2 0.74 9.7 0.0 2.4 1 1 1 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat Apc3 PF12895.2 CBZ55309.1 - 3.1e-13 49.6 0.4 1.7e-05 24.8 0.0 5.3 5 0 0 5 5 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.1 CBZ55309.1 - 1.2e-10 40.8 8.7 0.16 11.6 0.0 8.2 8 1 1 9 9 9 4 TPR repeat TPR_12 PF13424.1 CBZ55309.1 - 1.6e-10 40.7 19.0 0.31 11.0 0.2 8.5 7 2 1 8 8 8 4 Tetratricopeptide repeat TPR_19 PF14559.1 CBZ55309.1 - 3.8e-08 33.5 7.9 0.17 12.2 0.0 6.5 6 1 1 7 7 6 2 Tetratricopeptide repeat TPR_2 PF07719.12 CBZ55309.1 - 4.2e-07 29.3 10.6 0.077 12.9 0.0 9.2 10 0 0 10 10 10 1 Tetratricopeptide repeat TPR_1 PF00515.23 CBZ55309.1 - 6.7e-07 28.6 3.1 0.19 11.4 0.0 6.6 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_9 PF13371.1 CBZ55309.1 - 1.2e-06 28.2 16.0 0.0036 17.1 0.1 5.6 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_7 PF13176.1 CBZ55309.1 - 1.8e-06 27.2 12.5 3.8 7.5 0.1 8.9 10 0 0 10 10 10 2 Tetratricopeptide repeat TPR_16 PF13432.1 CBZ55309.1 - 8.2e-05 23.1 39.0 0.0031 18.1 0.3 9.4 8 3 3 11 11 11 3 Tetratricopeptide repeat TPR_6 PF13174.1 CBZ55309.1 - 0.00012 22.2 7.0 7.2 7.3 0.0 7.9 10 0 0 10 10 7 1 Tetratricopeptide repeat TPR_14 PF13428.1 CBZ55309.1 - 0.0006 20.2 33.1 0.74 10.6 0.0 11.3 10 2 3 13 13 11 2 Tetratricopeptide repeat TPR_8 PF13181.1 CBZ55309.1 - 0.0087 15.7 0.0 3.1 7.7 0.0 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat T2SM PF04612.7 CBZ55310.1 - 0.0074 16.0 3.2 0.29 10.8 0.0 2.1 1 1 1 2 2 2 1 Type II secretion system (T2SS), protein M SUKH_5 PF14567.1 CBZ55310.1 - 0.017 14.5 0.2 0.27 10.6 0.0 2.1 2 0 0 2 2 2 0 SMI1-KNR4 cell-wall OEP PF02321.13 CBZ55310.1 - 0.055 13.0 0.1 0.055 13.0 0.1 2.5 1 1 0 2 2 2 0 Outer membrane efflux protein FlbT PF07378.6 CBZ55310.1 - 0.11 12.3 1.5 3 7.7 0.0 2.2 2 0 0 2 2 2 0 Flagellar protein FlbT DUF4224 PF13986.1 CBZ55310.1 - 0.17 11.4 0.4 0.17 11.4 0.3 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4224) Exonuc_VII_L PF02601.10 CBZ55310.1 - 0.19 10.8 12.7 1.1 8.3 9.1 1.7 1 1 0 1 1 1 0 Exonuclease VII, large subunit DUF106 PF01956.11 CBZ55310.1 - 1.1 8.7 14.4 4.4 6.8 1.3 2.1 1 1 1 2 2 2 0 Integral membrane protein DUF106 DUF3166 PF11365.3 CBZ55310.1 - 1.1 9.6 12.0 4.1 7.9 0.1 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF3166) RmuC PF02646.11 CBZ55310.1 - 1.4 7.6 11.8 0.72 8.6 5.9 1.9 1 1 1 2 2 2 0 RmuC family APG6 PF04111.7 CBZ55310.1 - 2.2 7.2 13.9 3.3 6.6 9.6 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 ScpA_ScpB PF02616.9 CBZ55310.1 - 2.5 7.6 13.7 8.8 5.8 9.9 1.6 1 1 1 2 2 2 0 ScpA/B protein DUF2203 PF09969.4 CBZ55310.1 - 2.5 8.3 10.8 0.98 9.6 3.4 2.1 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) GrpE PF01025.14 CBZ55310.1 - 7.2 6.1 13.5 34 3.9 9.4 2.0 1 1 0 1 1 1 0 GrpE DUF342 PF03961.8 CBZ55310.1 - 8 4.7 17.9 28 2.9 12.5 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF342) Syntaxin-6_N PF09177.6 CBZ55310.1 - 8.4 6.8 9.0 3.6 8.0 1.6 2.2 1 1 1 2 2 2 0 Syntaxin 6, N-terminal RF-1 PF00472.15 CBZ55312.1 - 1.8e-34 117.9 0.6 1.8e-34 117.9 0.4 2.1 2 0 0 2 2 2 1 RF-1 domain PCRF PF03462.13 CBZ55312.1 - 8.2e-05 22.2 0.2 0.0003 20.4 0.1 1.9 1 0 0 1 1 1 1 PCRF domain Cwf_Cwc_15 PF04889.7 CBZ55312.1 - 1.4 8.5 9.9 5 6.7 0.3 2.9 3 0 0 3 3 3 0 Cwf15/Cwc15 cell cycle control protein AAR2 PF05282.6 CBZ55313.1 - 2.2e-46 158.4 0.0 1.8e-27 96.2 0.0 3.3 3 0 0 3 3 3 3 AAR2 protein Myb_DNA-binding PF00249.26 CBZ55313.1 - 0.57 10.2 4.8 11 6.1 0.1 2.7 2 0 0 2 2 2 0 Myb-like DNA-binding domain DUF982 PF06169.7 CBZ55314.1 - 0.03 14.0 0.0 0.053 13.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF982) Ribosomal_TL5_C PF14693.1 CBZ55315.1 - 0.00092 19.3 0.0 0.0013 18.9 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein TL5, C-terminal domain MMR_HSR1 PF01926.18 CBZ55316.1 - 5.8e-13 48.8 0.0 1.4e-12 47.5 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 CBZ55316.1 - 4e-05 22.9 0.0 6.7e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B AIG1 PF04548.11 CBZ55316.1 - 0.018 14.1 0.0 0.032 13.3 0.0 1.3 1 0 0 1 1 1 0 AIG1 family ABC_membrane_2 PF06472.10 CBZ55317.1 - 4.9e-65 219.4 0.7 7.9e-65 218.7 0.5 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.22 CBZ55317.1 - 1.5e-20 73.8 0.0 3.1e-20 72.8 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 CBZ55317.1 - 0.00078 19.4 0.0 0.0096 15.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain Arch_ATPase PF01637.13 CBZ55317.1 - 0.013 15.1 0.0 0.57 9.8 0.0 2.3 2 0 0 2 2 2 0 Archaeal ATPase IstB_IS21 PF01695.12 CBZ55317.1 - 0.085 12.2 0.0 0.19 11.1 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_10 PF12846.2 CBZ55317.1 - 0.22 10.9 0.6 10 5.4 0.0 2.2 2 0 0 2 2 2 0 AAA-like domain PduV-EutP PF10662.4 CBZ55317.1 - 0.23 10.9 0.0 1 8.8 0.0 2.0 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_23 PF13476.1 CBZ55317.1 - 0.48 10.7 0.1 0.96 9.7 0.1 1.4 1 0 0 1 1 1 0 AAA domain TraG-D_C PF12696.2 CBZ55317.1 - 0.55 10.0 0.0 0.55 10.0 0.0 3.2 3 0 0 3 3 3 0 TraM recognition site of TraD and TraG SNF PF00209.13 CBZ55318.1 - 2.6e-122 408.9 36.5 1.6e-118 396.5 24.1 3.0 2 1 0 2 2 2 2 Sodium:neurotransmitter symporter family DUF818 PF05677.7 CBZ55318.1 - 0.84 8.2 1.1 1.4 7.6 0.7 1.2 1 0 0 1 1 1 0 Chlamydia CHLPS protein (DUF818) WW PF00397.21 CBZ55319.1 - 9.8e-07 28.5 0.0 2.6e-06 27.1 0.0 1.8 1 0 0 1 1 1 1 WW domain Mago_nashi PF02792.9 CBZ55319.1 - 0.1 12.2 0.2 0.39 10.4 0.0 2.0 2 0 0 2 2 2 0 Mago nashi protein CKS PF01111.14 CBZ55321.1 - 0.15 11.9 0.1 0.59 10.0 0.1 1.8 1 1 0 1 1 1 0 Cyclin-dependent kinase regulatory subunit BSD PF03909.12 CBZ55322.1 - 0.00074 19.2 0.1 0.0015 18.2 0.1 1.4 1 0 0 1 1 1 1 BSD domain Transket_pyr PF02779.19 CBZ55323.1 - 2.1e-42 144.5 0.0 3.9e-42 143.7 0.0 1.5 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 CBZ55323.1 - 6.2e-36 123.0 0.0 1e-35 122.3 0.0 1.4 1 0 0 1 1 1 1 Transketolase, C-terminal domain DUF77 PF01910.12 CBZ55323.1 - 0.12 12.0 0.2 0.23 11.1 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function DUF77 AAA_12 PF13087.1 CBZ55324.1 - 3.4e-24 85.3 0.0 7.5e-24 84.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 CBZ55324.1 - 6.6e-24 84.7 0.0 6.6e-24 84.7 0.0 4.2 3 1 0 3 3 3 1 AAA domain AAA_19 PF13245.1 CBZ55324.1 - 5.1e-08 32.5 0.0 2e-07 30.6 0.0 2.0 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 CBZ55324.1 - 0.0019 18.3 0.1 0.022 14.8 0.0 2.7 3 0 0 3 3 3 1 AAA domain AAA_5 PF07728.9 CBZ55324.1 - 0.0022 17.7 0.0 0.0066 16.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 CBZ55324.1 - 0.0022 17.4 0.0 0.0059 16.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.17 CBZ55324.1 - 0.0036 16.7 0.0 0.007 15.8 0.0 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain AAA PF00004.24 CBZ55324.1 - 0.029 14.5 0.0 0.2 11.8 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DEAD PF00270.24 CBZ55324.1 - 0.15 11.5 0.0 0.66 9.4 0.0 2.0 2 0 0 2 2 2 0 DEAD/DEAH box helicase AAA_17 PF13207.1 CBZ55324.1 - 0.37 11.6 0.0 0.37 11.6 0.0 3.0 3 0 0 3 3 3 0 AAA domain Clat_adaptor_s PF01217.15 CBZ55326.1 - 2.3e-44 150.5 4.6 2.5e-44 150.4 3.2 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DSPn PF14671.1 CBZ55327.1 - 4.4e-50 169.3 0.0 1.3e-49 167.7 0.0 1.8 2 0 0 2 2 2 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.15 CBZ55327.1 - 2e-10 40.3 0.0 4.5e-10 39.2 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 CBZ55327.1 - 5.4e-06 25.9 0.0 8.8e-06 25.2 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase2 PF03162.8 CBZ55327.1 - 3e-05 23.4 0.0 5.5e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.1 CBZ55327.1 - 0.0014 18.6 0.1 0.0026 17.8 0.0 1.4 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.1 CBZ55327.1 - 0.0014 18.8 0.1 0.0046 17.2 0.0 1.7 1 1 1 2 2 2 1 Tyrosine phosphatase family Peptidase_S8 PF00082.17 CBZ55332.1 - 4.3e-49 167.1 2.0 7.6e-49 166.3 1.4 1.4 1 0 0 1 1 1 1 Subtilase family Cornifin PF02389.10 CBZ55332.1 - 1.5e-21 77.1 46.6 8.2e-15 55.1 11.7 2.5 2 1 1 3 3 3 2 Cornifin (SPRR) family DUF4231 PF14015.1 CBZ55332.1 - 2.9 7.9 5.7 15 5.6 0.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) Ndc1_Nup PF09531.5 CBZ55332.1 - 4.1 5.7 4.8 6.4 5.0 3.3 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup RPAP1_C PF08620.5 CBZ55334.1 - 1.2e-16 60.2 0.0 3.6e-16 58.7 0.0 1.9 1 1 0 1 1 1 1 RPAP1-like, C-terminal RPAP1_N PF08621.5 CBZ55334.1 - 0.00013 21.4 4.4 0.00031 20.2 3.1 1.6 1 0 0 1 1 1 1 RPAP1-like, N-terminal DPPIV_N PF00930.16 CBZ55334.1 - 2.9 6.3 0.1 4.9 5.6 0.1 1.2 1 0 0 1 1 1 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region Mito_carr PF00153.22 CBZ55338.1 - 2.4e-33 113.6 0.6 2.2e-13 49.7 0.1 3.9 3 1 0 3 3 3 3 Mitochondrial carrier protein FGGY_C PF02782.11 CBZ55338.1 - 0.016 14.8 0.2 1.1 8.8 0.0 2.2 2 0 0 2 2 2 0 FGGY family of carbohydrate kinases, C-terminal domain Sedlin_N PF04628.8 CBZ55339.1 - 4.8e-20 71.7 0.0 5.8e-20 71.5 0.0 1.1 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.7 CBZ55339.1 - 0.063 12.9 0.0 0.093 12.4 0.0 1.2 1 0 0 1 1 1 0 Sybindin-like family Alg6_Alg8 PF03155.10 CBZ55340.1 - 1e-94 318.0 18.9 1.3e-57 195.7 3.5 3.3 3 1 0 3 3 3 3 ALG6, ALG8 glycosyltransferase family DUF382 PF04037.8 CBZ55341.1 - 1.2e-53 180.3 1.5 1.6e-53 179.9 0.1 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF382) PSP PF04046.11 CBZ55341.1 - 2.9e-19 68.1 5.8 6.1e-19 67.1 4.0 1.6 1 0 0 1 1 1 1 PSP CTD PF12815.2 CBZ55341.1 - 0.011 16.1 14.9 0.03 14.7 3.9 3.3 2 1 1 3 3 3 0 Spt5 C-terminal nonapeptide repeat binding Spt4 Ycf1 PF05758.7 CBZ55341.1 - 1.1 6.8 4.5 2.4 5.7 3.1 1.4 1 0 0 1 1 1 0 Ycf1 Ribosomal_L1 PF00687.16 CBZ55342.1 - 1.4e-43 148.8 0.1 2.2e-43 148.1 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family CRAL_TRIO_2 PF13716.1 CBZ55342.1 - 0.081 12.8 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain tRNA_m1G_MT PF01746.16 CBZ55343.1 - 3e-16 59.5 0.0 4.1e-16 59.1 0.0 1.2 1 0 0 1 1 1 1 tRNA (Guanine-1)-methyltransferase Myosin_head PF00063.16 CBZ55344.1 - 1.6e-47 162.0 0.0 3.3e-34 118.0 0.0 3.2 2 1 1 3 3 3 3 Myosin head (motor domain) MyTH4 PF00784.12 CBZ55344.1 - 7.3e-18 64.5 0.1 6.9e-17 61.4 0.0 2.4 2 0 0 2 2 2 1 MyTH4 domain IQ PF00612.22 CBZ55344.1 - 0.027 14.0 2.6 0.1 12.2 1.8 2.1 1 0 0 1 1 1 0 IQ calmodulin-binding motif LSM PF01423.17 CBZ55345.1 - 9.8e-16 57.0 0.1 1.4e-15 56.6 0.1 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 CBZ55345.1 - 0.059 13.2 0.1 0.092 12.6 0.0 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain zf-met2 PF12907.2 CBZ55346.1 - 1.8e-20 72.5 5.5 3.5e-20 71.6 3.8 1.5 1 0 0 1 1 1 1 Zinc-binding 4F5 PF04419.9 CBZ55346.1 - 4e-05 24.2 5.8 7.5e-05 23.3 4.0 1.5 1 0 0 1 1 1 1 4F5 protein family zf-BED PF02892.10 CBZ55346.1 - 0.15 11.7 0.5 0.43 10.3 0.1 1.9 2 0 0 2 2 2 0 BED zinc finger Ribosomal_L30 PF00327.15 CBZ55347.1 - 5.9e-16 57.7 3.0 1.2e-15 56.7 0.8 2.2 2 0 0 2 2 2 1 Ribosomal protein L30p/L7e Ribosomal_L30_N PF08079.7 CBZ55347.1 - 6e-11 42.2 13.3 1.1e-10 41.4 9.2 1.4 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain ATP-synt_Eps PF04627.8 CBZ55348.1 - 1.1e-11 44.0 0.9 1.4e-11 43.7 0.1 1.5 2 0 0 2 2 2 1 Mitochondrial ATP synthase epsilon chain SF3b10 PF07189.6 CBZ55349.1 - 6e-33 112.5 0.1 7.1e-33 112.2 0.0 1.1 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) UCH PF00443.24 CBZ55350.1 - 6e-23 81.3 0.0 5.2e-12 45.4 0.0 2.7 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CBZ55350.1 - 0.00073 19.0 0.0 0.89 8.9 0.0 3.2 3 1 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase Peptidase_M16_C PF05193.16 CBZ55351.1 - 0.0015 18.2 0.1 0.044 13.4 0.0 2.8 1 1 0 1 1 1 1 Peptidase M16 inactive domain KH_1 PF00013.24 CBZ55352.1 - 6.7e-09 35.2 0.1 1.2e-08 34.4 0.1 1.4 1 0 0 1 1 1 1 KH domain KH_3 PF13014.1 CBZ55352.1 - 0.00067 19.2 0.3 0.0016 18.0 0.2 1.7 1 0 0 1 1 1 1 KH domain zf-CCHC_4 PF14392.1 CBZ55352.1 - 0.0013 18.3 2.3 0.26 10.9 0.0 2.4 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC PF00098.18 CBZ55352.1 - 0.0091 15.8 7.1 0.027 14.4 0.8 2.6 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_3 PF13917.1 CBZ55352.1 - 0.0096 15.6 4.1 0.24 11.1 0.0 2.4 1 1 1 2 2 2 2 Zinc knuckle DUF4206 PF13901.1 CBZ55352.1 - 0.015 14.8 0.3 0.022 14.2 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4206) zf-CCHC_6 PF15288.1 CBZ55352.1 - 0.073 12.7 2.9 1.1 8.9 0.2 2.7 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_2 PF13696.1 CBZ55352.1 - 0.076 12.5 4.4 1.7 8.1 0.5 3.1 1 1 1 2 2 2 0 Zinc knuckle RIC1 PF07064.8 CBZ55353.1 - 6.8e-12 45.3 0.0 6.3e-11 42.2 0.0 2.2 2 1 0 2 2 2 1 RIC1 ThiF PF00899.16 CBZ55354.1 - 5e-32 110.5 4.2 4.7e-21 75.0 0.0 3.5 3 0 0 3 3 3 3 ThiF family UBACT PF02134.16 CBZ55354.1 - 5.6e-14 51.4 0.0 6.9e-10 38.3 0.0 3.0 3 0 0 3 3 3 2 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 CBZ55354.1 - 8.7e-10 37.8 0.0 2e-09 36.6 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site CLTH PF10607.4 CBZ55355.1 - 3.2e-25 88.5 1.2 4e-25 88.1 0.8 1.1 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.6 CBZ55355.1 - 7.1e-05 22.4 0.1 0.00017 21.2 0.0 1.7 1 0 0 1 1 1 1 LisH CBM_20 PF00686.14 CBZ55356.1 - 8.8e-21 73.3 0.3 1.3e-20 72.8 0.2 1.2 1 0 0 1 1 1 1 Starch binding domain DUF1374 PF07118.6 CBZ55356.1 - 0.0047 17.0 0.3 0.016 15.3 0.0 1.9 2 1 0 2 2 2 1 Protein of unknown function (DUF1374) Arb2 PF09757.4 CBZ55356.1 - 0.015 14.7 0.1 0.02 14.3 0.1 1.2 1 0 0 1 1 1 0 Arb2 domain CBM_48 PF02922.13 CBZ55356.1 - 0.051 13.6 0.1 0.085 12.9 0.0 1.3 1 0 0 1 1 1 0 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) DUF1528 PF07515.6 CBZ55356.1 - 0.14 12.2 0.2 0.39 10.7 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1528) DNA_ligase_aden PF01653.13 CBZ55358.1 - 1.6e-28 99.6 0.0 5.6e-11 41.9 0.0 5.1 5 0 0 5 5 5 4 NAD-dependent DNA ligase adenylation domain DNA_ligase_OB PF03120.11 CBZ55358.1 - 9.5e-12 44.4 0.0 1.8e-11 43.5 0.0 1.4 1 0 0 1 1 1 1 NAD-dependent DNA ligase OB-fold domain RHD3 PF05879.7 CBZ55359.1 - 1.8e-127 426.2 0.0 2.3e-127 425.9 0.0 1.0 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) GBP PF02263.14 CBZ55359.1 - 9.6e-06 24.8 0.2 2.2e-05 23.6 0.0 1.6 2 0 0 2 2 2 1 Guanylate-binding protein, N-terminal domain MMR_HSR1 PF01926.18 CBZ55359.1 - 2.5e-05 24.1 0.0 7.4e-05 22.6 0.0 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 CBZ55359.1 - 0.00027 20.8 0.1 0.00066 19.5 0.0 1.7 1 0 0 1 1 1 1 Dynamin family Miro PF08477.8 CBZ55359.1 - 0.019 15.4 0.0 0.052 14.0 0.0 1.8 2 0 0 2 2 2 0 Miro-like protein AAA_23 PF13476.1 CBZ55359.1 - 0.049 13.9 0.0 1.2 9.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.1 CBZ55359.1 - 0.069 13.1 1.4 0.17 11.8 0.0 2.4 3 0 0 3 3 3 0 AAA domain AAA_29 PF13555.1 CBZ55359.1 - 0.092 12.2 0.0 0.36 10.3 0.0 2.0 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF2244 PF10003.4 CBZ55359.1 - 1.6 8.0 8.8 3.3 7.0 6.1 1.4 1 0 0 1 1 1 0 Integral membrane protein (DUF2244) PI-PLC-X PF00388.14 CBZ55360.1 - 0.002 17.5 0.0 0.005 16.2 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain Prefoldin PF02996.12 CBZ55363.1 - 2.2e-24 85.4 1.8 3e-24 84.9 1.3 1.2 1 0 0 1 1 1 1 Prefoldin subunit GAS PF13851.1 CBZ55363.1 - 0.0002 20.6 4.7 0.01 15.0 1.8 2.0 2 0 0 2 2 2 2 Growth-arrest specific micro-tubule binding Prefoldin_3 PF13758.1 CBZ55363.1 - 0.031 14.0 0.3 0.06 13.1 0.2 1.6 1 1 0 1 1 1 0 Prefoldin subunit Prefoldin_2 PF01920.15 CBZ55363.1 - 0.041 13.6 10.4 0.31 10.8 2.9 2.4 2 1 0 2 2 2 0 Prefoldin subunit DUF970 PF06153.6 CBZ55363.1 - 0.042 13.8 0.2 0.075 13.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF970) YscO PF07321.7 CBZ55363.1 - 1.4 8.7 13.7 0.53 10.0 0.8 2.1 2 0 0 2 2 2 0 Type III secretion protein YscO DUF4200 PF13863.1 CBZ55363.1 - 1.7 8.5 9.5 18 5.2 3.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) COG2 PF06148.6 CBZ55363.1 - 5.2 6.9 7.4 1.4e+02 2.3 5.1 2.1 1 1 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 TFIID_30kDa PF03540.8 CBZ55364.1 - 6.9e-06 25.7 0.0 1.2e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit PCMT PF01135.14 CBZ55366.1 - 3.8e-60 203.0 0.0 2.8e-55 187.1 0.0 2.1 2 0 0 2 2 2 2 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_18 PF12847.2 CBZ55366.1 - 0.0016 19.0 0.0 0.0031 18.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CBZ55366.1 - 0.0075 15.9 0.0 0.013 15.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CBZ55366.1 - 0.024 14.2 0.0 0.039 13.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain WD40 PF00400.27 CBZ55367.1 - 3.4e-13 48.9 1.5 8.9e-05 22.2 0.1 4.4 4 0 0 4 4 4 3 WD domain, G-beta repeat IF4E PF01652.13 CBZ55368.1 - 5.4e-31 107.3 0.0 1.1e-30 106.2 0.0 1.5 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Ycf1 PF05758.7 CBZ55368.1 - 0.22 9.2 13.0 0.13 9.9 5.7 2.0 2 0 0 2 2 2 0 Ycf1 Mem_trans PF03547.13 CBZ55368.1 - 1.1 7.5 3.3 0.5 8.6 0.0 1.8 2 0 0 2 2 2 0 Membrane transport protein CDC27 PF09507.5 CBZ55368.1 - 4.1 6.5 40.8 1.1 8.3 17.4 2.1 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 MAM PF00629.18 CBZ55369.1 - 0.0027 17.4 0.7 0.02 14.6 0.1 2.2 2 0 0 2 2 2 1 MAM domain NT-C2 PF10358.4 CBZ55369.1 - 0.039 13.4 0.3 0.075 12.5 0.2 1.6 1 0 0 1 1 1 0 N-terminal C2 in EEIG1 and EHBP1 proteins Takusan PF04822.8 CBZ55369.1 - 0.16 11.7 3.7 1.8 8.3 0.3 2.5 2 0 0 2 2 2 0 Takusan SLA_LP_auto_ag PF05889.8 CBZ55370.1 - 2.7e-110 368.4 0.0 3.3e-99 332.0 0.0 4.0 2 1 1 4 4 4 4 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) Beta_elim_lyase PF01212.16 CBZ55370.1 - 0.0024 17.0 0.0 0.0035 16.5 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Pyridoxal_deC PF00282.14 CBZ55370.1 - 0.018 13.5 0.0 0.026 12.9 0.0 1.1 1 0 0 1 1 1 0 Pyridoxal-dependent decarboxylase conserved domain Pkinase PF00069.20 CBZ55371.1 - 3.7e-71 239.3 0.0 4.9e-71 238.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ55371.1 - 3.2e-32 111.6 0.0 4.7e-32 111.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.24 CBZ55371.1 - 0.0011 19.1 0.0 0.0022 18.1 0.0 1.5 1 0 0 1 1 1 1 PH domain Kdo PF06293.9 CBZ55371.1 - 0.075 12.0 0.0 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family LMF1 PF06762.9 CBZ55372.1 - 7.8e-129 429.8 2.5 5.2e-81 272.3 0.2 2.5 1 1 1 2 2 2 2 Lipase maturation factor GCS PF03074.11 CBZ55372.1 - 0.032 13.2 0.0 0.065 12.2 0.0 1.4 1 0 0 1 1 1 0 Glutamate-cysteine ligase MIP-T3 PF10243.4 CBZ55372.1 - 2.3 6.5 82.8 3.2 6.1 57.4 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 LMF1 PF06762.9 CBZ55373.1 - 1.1e-156 521.4 6.3 1.8e-156 520.8 4.4 1.3 1 0 0 1 1 1 1 Lipase maturation factor Transglut_core PF01841.14 CBZ55373.1 - 0.015 15.5 0.0 0.065 13.4 0.0 2.1 1 0 0 1 1 1 0 Transglutaminase-like superfamily Nuc_recep-AF1 PF11825.3 CBZ55373.1 - 0.14 12.1 0.0 0.26 11.2 0.0 1.3 1 0 0 1 1 1 0 Nuclear/hormone receptor activator site AF-1 Rapsyn_N PF10579.4 CBZ55374.1 - 0.0011 18.7 0.0 0.0055 16.4 0.0 2.1 2 0 0 2 2 2 1 Rapsyn N-terminal myristoylation and linker region TPR_12 PF13424.1 CBZ55374.1 - 0.077 12.9 0.4 2.9 7.9 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat UPF0160 PF03690.8 CBZ55376.1 - 2e-97 326.4 0.0 7.3e-62 209.6 0.0 2.5 2 1 0 2 2 2 2 Uncharacterised protein family (UPF0160) AlaDh_PNT_N PF05222.10 CBZ55377.1 - 9.8e-44 148.6 0.0 1.5e-43 148.0 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain AlaDh_PNT_C PF01262.16 CBZ55377.1 - 9.6e-42 142.3 1.1 1e-41 142.3 0.0 1.6 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.14 CBZ55377.1 - 1.6e-06 27.3 0.0 4e-05 22.8 0.0 2.3 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 CBZ55377.1 - 3.9e-05 23.7 0.0 6.6e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.13 CBZ55377.1 - 0.00064 19.7 0.4 0.0043 17.0 0.0 2.4 2 1 1 3 3 3 1 TrkA-N domain GIDA PF01134.17 CBZ55377.1 - 0.0007 18.5 0.5 0.00095 18.1 0.3 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox_2 PF07992.9 CBZ55377.1 - 0.00075 19.4 0.1 0.0011 18.8 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 CBZ55377.1 - 0.0016 18.7 0.2 0.0036 17.6 0.1 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 CBZ55377.1 - 0.0022 16.9 2.0 0.0039 16.1 1.4 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase UDPG_MGDP_dh_N PF03721.9 CBZ55377.1 - 0.0028 17.0 0.0 0.022 14.1 0.0 2.2 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3HCDH_N PF02737.13 CBZ55377.1 - 0.008 15.8 1.0 0.015 14.9 0.2 1.8 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_7 PF13241.1 CBZ55377.1 - 0.017 15.3 0.1 0.041 14.1 0.1 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding NAD_binding_8 PF13450.1 CBZ55377.1 - 0.042 13.8 1.1 0.042 13.8 0.8 2.2 3 0 0 3 3 3 0 NAD(P)-binding Rossmann-like domain AdoHcyase_NAD PF00670.16 CBZ55377.1 - 0.062 13.1 0.3 0.23 11.2 0.2 2.0 1 1 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain HI0933_like PF03486.9 CBZ55377.1 - 0.18 10.2 1.0 0.24 9.8 0.7 1.1 1 0 0 1 1 1 0 HI0933-like protein FAD_binding_2 PF00890.19 CBZ55377.1 - 0.27 10.0 2.5 0.39 9.4 1.7 1.2 1 0 0 1 1 1 0 FAD binding domain FAD_oxidored PF12831.2 CBZ55377.1 - 0.3 10.0 4.5 0.46 9.5 3.1 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase FlxA PF14282.1 CBZ55379.1 - 0.38 10.7 10.2 0.072 13.0 3.9 2.2 2 0 0 2 2 2 0 FlxA-like protein DUF667 PF05018.8 CBZ55381.1 - 1.5e-102 340.7 0.5 1.7e-102 340.5 0.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF667) Arena_RNA_pol PF06317.6 CBZ55381.1 - 0.07 9.7 0.0 0.093 9.3 0.0 1.2 1 0 0 1 1 1 0 Arenavirus RNA polymerase SAG PF04092.8 CBZ55383.1 - 2.1e-21 76.6 13.1 2.1e-10 41.0 0.4 2.1 2 0 0 2 2 2 2 SRS domain SAG PF04092.8 CBZ55384.1 - 9.8e-25 87.3 11.9 1.7e-13 51.0 1.5 2.1 2 0 0 2 2 2 2 SRS domain SAG PF04092.8 CBZ55385.1 - 2.8e-22 79.4 11.4 7.4e-12 45.7 0.2 2.1 2 0 0 2 2 2 2 SRS domain SAG PF04092.8 CBZ55386.1 - 5.8e-21 75.1 16.4 2.5e-10 40.7 4.0 3.1 3 0 0 3 3 3 2 SRS domain SAG PF04092.8 CBZ55387.1 - 1.3e-25 90.1 15.1 6.3e-15 55.6 0.8 2.1 2 0 0 2 2 2 2 SRS domain DUF1101 PF06503.6 CBZ55387.1 - 0.14 10.8 0.0 0.24 10.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1101) SAG PF04092.8 CBZ55388.1 - 4.6e-25 88.4 12.6 2.9e-13 50.2 0.6 2.2 2 0 0 2 2 2 2 SRS domain Hox9_act PF04617.8 CBZ55388.1 - 0.025 14.7 0.1 0.057 13.5 0.0 1.6 2 0 0 2 2 2 0 Hox9 activation region Mg_trans_NIPA PF05653.9 CBZ55390.1 - 2.3e-11 43.2 15.0 8.2e-08 31.5 1.7 2.1 1 1 1 2 2 2 2 Magnesium transporter NIPA EmrE PF13536.1 CBZ55390.1 - 6.1e-07 29.6 4.9 6.1e-07 29.6 3.4 3.0 2 1 1 3 3 3 1 Multidrug resistance efflux transporter EamA PF00892.15 CBZ55390.1 - 2e-05 24.6 5.1 2e-05 24.6 3.5 2.3 2 0 0 2 2 2 1 EamA-like transporter family Saccharop_dh PF03435.13 CBZ55391.1 - 6.2e-09 35.3 0.0 1.5e-08 34.0 0.0 1.6 2 0 0 2 2 2 1 Saccharopine dehydrogenase DUF1510 PF07423.6 CBZ55393.1 - 0.27 10.5 0.0 0.27 10.5 0.0 3.5 3 1 1 4 4 4 0 Protein of unknown function (DUF1510) DUF4446 PF14584.1 CBZ55393.1 - 0.85 9.4 0.0 0.85 9.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) Neur_chan_memb PF02932.11 CBZ55393.1 - 4.4 7.1 0.0 4.4 7.1 0.0 3.2 2 1 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Acyl-CoA_dh_M PF02770.14 CBZ55394.1 - 7.4e-10 38.1 0.1 1.4e-09 37.3 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.19 CBZ55394.1 - 0.0006 19.9 0.0 0.0012 19.0 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain EGF_CA PF07645.10 CBZ55398.1 - 1.3e-21 76.2 81.6 3.1e-09 36.6 5.5 6.4 6 0 0 6 6 6 4 Calcium-binding EGF domain EGF_3 PF12947.2 CBZ55398.1 - 4.4e-18 64.9 74.8 2.3e-07 30.6 8.5 7.0 6 2 0 6 6 6 5 EGF domain cEGF PF12662.2 CBZ55398.1 - 8e-12 44.5 48.7 1.2e-06 28.0 1.8 7.6 7 1 0 7 7 7 4 Complement Clr-like EGF-like FXa_inhibition PF14670.1 CBZ55398.1 - 3.4e-07 30.2 80.1 1.9e-05 24.6 6.7 6.6 6 0 0 6 6 6 4 Coagulation Factor Xa inhibitory site EGF PF00008.22 CBZ55398.1 - 8.8e-05 22.3 69.8 0.0055 16.6 3.4 7.3 7 1 1 8 8 8 5 EGF-like domain EGF_MSP1_1 PF12946.2 CBZ55398.1 - 0.00035 20.3 4.8 0.00035 20.3 3.3 5.9 6 0 0 6 6 6 2 MSP1 EGF domain 1 Orthoreo_P10 PF07204.6 CBZ55398.1 - 0.089 12.5 2.4 0.11 12.2 0.1 2.3 2 0 0 2 2 2 0 Orthoreovirus membrane fusion protein p10 hEGF PF12661.2 CBZ55398.1 - 0.32 11.1 23.0 0.15 12.2 0.6 6.0 5 0 0 5 5 5 0 Human growth factor-like EGF Vps39_2 PF10367.4 CBZ55399.1 - 1.5e-22 79.7 0.0 4.6e-22 78.2 0.0 1.9 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 2 CNH PF00780.17 CBZ55399.1 - 3.7e-12 46.2 0.0 1.1e-11 44.6 0.0 1.7 1 1 0 1 1 1 1 CNH domain Clathrin PF00637.15 CBZ55399.1 - 5.1e-05 22.9 0.0 0.00014 21.4 0.0 1.7 1 0 0 1 1 1 1 Region in Clathrin and VPS KH_4 PF13083.1 CBZ55399.1 - 0.058 13.0 0.0 0.18 11.4 0.0 1.8 1 0 0 1 1 1 0 KH domain Vps39_1 PF10366.4 CBZ55399.1 - 0.065 13.2 0.1 0.26 11.3 0.0 2.1 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 1 EGF_CA PF07645.10 CBZ55400.1 - 2.4e-13 49.8 50.6 5.3e-11 42.3 6.3 4.1 4 0 0 4 4 4 3 Calcium-binding EGF domain EGF_3 PF12947.2 CBZ55400.1 - 2.6e-12 46.4 50.5 1.3e-05 25.0 3.7 5.7 5 1 1 6 6 6 3 EGF domain EGF_MSP1_1 PF12946.2 CBZ55400.1 - 2e-07 30.6 2.8 2e-07 30.6 1.9 4.0 4 0 0 4 4 4 1 MSP1 EGF domain 1 FXa_inhibition PF14670.1 CBZ55400.1 - 3e-05 24.0 47.4 0.00051 20.1 4.6 4.5 4 0 0 4 4 4 3 Coagulation Factor Xa inhibitory site cEGF PF12662.2 CBZ55400.1 - 0.00058 19.4 13.5 0.0029 17.1 2.2 4.0 4 0 0 4 4 4 2 Complement Clr-like EGF-like EGF PF00008.22 CBZ55400.1 - 0.0012 18.7 5.5 0.0012 18.7 3.8 5.3 5 2 0 5 5 5 2 EGF-like domain EGF_2 PF07974.8 CBZ55400.1 - 0.027 14.6 6.3 0.027 14.6 4.3 4.6 4 0 0 4 4 4 0 EGF-like domain hEGF PF12661.2 CBZ55400.1 - 4.8 7.4 10.7 12 6.2 0.1 4.2 3 0 0 3 3 3 0 Human growth factor-like EGF EGF_CA PF07645.10 CBZ55401.1 - 3.4e-18 65.3 55.3 5.1e-09 35.9 7.7 4.2 4 0 0 4 4 4 4 Calcium-binding EGF domain EGF_3 PF12947.2 CBZ55401.1 - 1.2e-07 31.5 53.6 0.0021 17.9 7.4 4.5 4 0 0 4 4 4 3 EGF domain cEGF PF12662.2 CBZ55401.1 - 1.9e-05 24.2 13.0 0.0011 18.5 2.3 4.4 5 0 0 5 5 5 2 Complement Clr-like EGF-like EGF PF00008.22 CBZ55401.1 - 0.0003 20.6 7.9 0.0003 20.6 5.5 4.6 4 0 0 4 4 4 3 EGF-like domain FXa_inhibition PF14670.1 CBZ55401.1 - 0.0015 18.6 53.4 0.0072 16.4 5.2 4.3 4 0 0 4 4 4 3 Coagulation Factor Xa inhibitory site EGF_MSP1_1 PF12946.2 CBZ55401.1 - 0.0038 16.9 8.0 0.0038 16.9 5.6 3.9 4 0 0 4 4 4 3 MSP1 EGF domain 1 DUF1191 PF06697.7 CBZ55401.1 - 0.0056 15.5 0.0 0.0084 14.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1191) ABC2_membrane PF01061.19 CBZ55402.1 - 2.5e-29 101.9 8.4 3.6e-29 101.4 5.8 1.2 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.22 CBZ55402.1 - 3.7e-27 95.3 0.0 1.2e-26 93.6 0.0 2.0 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.1 CBZ55402.1 - 1.8e-07 31.3 1.4 0.0005 20.1 0.1 2.3 1 1 0 2 2 2 2 AAA domain AAA_25 PF13481.1 CBZ55402.1 - 8.3e-06 25.3 0.1 0.00062 19.2 0.1 2.5 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 CBZ55402.1 - 6e-05 22.2 0.0 0.031 13.4 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_29 PF13555.1 CBZ55402.1 - 0.0015 18.0 0.9 0.098 12.1 0.1 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_17 PF13207.1 CBZ55402.1 - 0.036 14.9 0.0 0.082 13.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF87 PF01935.12 CBZ55402.1 - 0.062 13.1 0.6 0.15 11.8 0.4 1.5 1 0 0 1 1 1 0 Domain of unknown function DUF87 AAA_23 PF13476.1 CBZ55402.1 - 0.4 10.9 1.0 0.85 9.9 0.3 1.7 2 0 0 2 2 2 0 AAA domain HC2 PF07382.6 CBZ55403.1 - 0.69 9.7 50.1 1.1 9.0 34.7 1.4 1 1 0 1 1 1 0 Histone H1-like nucleoprotein HC2 KAAG1 PF15354.1 CBZ55403.1 - 0.86 9.9 6.9 0.86 9.9 3.7 1.7 1 1 1 2 2 2 0 Kidney-associated antigen 1 Abhydrolase_1 PF00561.15 CBZ55404.1 - 8.1e-06 25.5 0.0 2e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 CBZ55404.1 - 3.7e-05 23.5 0.0 0.00011 21.9 0.0 1.8 1 0 0 1 1 1 1 Alpha/beta hydrolase family Lipase_3 PF01764.20 CBZ55404.1 - 0.0031 17.1 0.0 0.0059 16.2 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) CRAL_TRIO_2 PF13716.1 CBZ55405.1 - 3.7e-21 75.5 0.2 8.5e-21 74.4 0.1 1.7 2 0 0 2 2 2 1 Divergent CRAL/TRIO domain Macro PF01661.16 CBZ55405.1 - 6e-13 48.7 0.0 1.2e-12 47.7 0.0 1.5 1 0 0 1 1 1 1 Macro domain CRAL_TRIO PF00650.15 CBZ55405.1 - 0.001 18.5 0.0 0.0021 17.5 0.0 1.5 1 0 0 1 1 1 1 CRAL/TRIO domain DUF2362 PF10154.4 CBZ55405.1 - 0.0015 17.3 0.0 0.0023 16.7 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2362) MCM PF00493.18 CBZ55406.1 - 1.4e-83 280.4 0.0 2.6e-69 233.5 0.0 3.2 3 0 0 3 3 3 3 MCM2/3/5 family AAA_5 PF07728.9 CBZ55406.1 - 3.4e-05 23.6 0.0 0.22 11.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 CBZ55406.1 - 5.8e-05 22.3 0.4 0.0048 16.0 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_16 PF13191.1 CBZ55406.1 - 0.0029 17.6 0.4 0.043 13.7 0.2 2.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_3 PF07726.6 CBZ55406.1 - 0.019 14.5 0.0 0.12 11.9 0.0 2.3 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 CBZ55406.1 - 0.021 14.2 0.0 3.7 7.0 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_2 PF07724.9 CBZ55406.1 - 0.063 13.1 0.0 0.29 11.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain (Cdc48 subfamily) V-ATPase_C PF03223.10 CBZ55408.1 - 2.9e-94 316.0 0.0 3.3e-94 315.8 0.0 1.0 1 0 0 1 1 1 1 V-ATPase subunit C DUF2722 PF10846.3 CBZ55408.1 - 0.043 12.8 0.9 0.064 12.2 0.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) BPL_LplA_LipB PF03099.14 CBZ55409.1 - 5.9e-11 42.4 0.2 1.4e-09 38.0 0.2 2.2 1 1 0 1 1 1 1 Biotin/lipoate A/B protein ligase family TPR_11 PF13414.1 CBZ55410.1 - 0.00095 18.7 5.5 0.028 14.0 0.2 4.2 5 0 0 5 5 5 1 TPR repeat TPR_12 PF13424.1 CBZ55410.1 - 0.063 13.2 7.8 7.1 6.6 0.1 4.4 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.1 CBZ55410.1 - 0.068 13.8 20.7 1.9 9.3 0.1 7.4 5 2 2 7 7 7 0 Tetratricopeptide repeat TPR_4 PF07721.9 CBZ55410.1 - 0.069 13.6 0.6 0.069 13.6 0.4 5.3 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_20 PF14561.1 CBZ55410.1 - 0.17 12.0 3.1 3.6 7.7 0.1 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat SR-25 PF10500.4 CBZ55410.1 - 0.69 9.3 16.9 1.7 8.0 11.7 1.6 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Herpes_capsid PF06112.6 CBZ55410.1 - 1 9.4 9.2 2.9 7.9 6.4 1.7 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein TPR_19 PF14559.1 CBZ55410.1 - 1.3 9.4 14.0 3.7 7.9 0.9 5.3 6 1 0 6 6 6 0 Tetratricopeptide repeat TPR_16 PF13432.1 CBZ55410.1 - 1.3 9.7 22.8 1.8 9.3 0.2 5.8 5 3 1 6 6 6 0 Tetratricopeptide repeat TPR_2 PF07719.12 CBZ55410.1 - 3.8 7.6 8.0 18 5.5 0.0 4.9 6 0 0 6 6 6 0 Tetratricopeptide repeat HEAT PF02985.17 CBZ55411.1 - 1.5e-17 61.9 16.6 0.016 15.2 0.1 8.6 8 0 0 8 8 8 6 HEAT repeat HEAT_2 PF13646.1 CBZ55411.1 - 2.8e-13 49.9 9.4 5.2e-06 26.6 0.1 6.5 5 2 0 5 5 5 3 HEAT repeats HEAT_EZ PF13513.1 CBZ55411.1 - 0.0038 17.6 21.8 0.081 13.4 0.3 8.8 8 2 1 9 9 9 1 HEAT-like repeat Vac14_Fab1_bd PF12755.2 CBZ55411.1 - 0.008 16.5 0.0 0.77 10.1 0.0 2.9 3 0 0 3 3 3 1 Vacuolar 14 Fab1-binding region AAA PF00004.24 CBZ55412.1 - 3.4e-28 98.4 0.0 6.6e-28 97.5 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.5 CBZ55412.1 - 1.2e-22 79.5 0.0 2.7e-22 78.4 0.0 1.6 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain MIT PF04212.13 CBZ55412.1 - 1.1e-12 47.6 0.7 2e-12 46.7 0.5 1.5 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain DnaJ PF00226.26 CBZ55413.1 - 8e-23 79.9 1.2 2.1e-22 78.5 0.9 1.8 1 0 0 1 1 1 1 DnaJ domain TPR_6 PF13174.1 CBZ55413.1 - 4.7 7.8 5.8 25 5.6 0.1 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat Orbi_VP5 PF00901.12 CBZ55413.1 - 5.3 5.1 12.0 2.5 6.2 4.9 2.0 2 0 0 2 2 2 0 Orbivirus outer capsid protein VP5 GYF PF02213.11 CBZ55414.1 - 7.9e-09 34.9 0.3 1.4e-08 34.1 0.2 1.4 1 0 0 1 1 1 1 GYF domain zf-His_Me_endon PF05551.6 CBZ55415.1 - 0.039 13.9 0.0 0.06 13.3 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding loop region of homing endonuclease SCAMP PF04144.8 CBZ55416.1 - 2.6e-06 27.4 1.0 3.7e-06 26.9 0.7 1.3 1 1 0 1 1 1 1 SCAMP family CENP-C_C PF11699.3 CBZ55416.1 - 0.058 13.3 0.0 0.45 10.5 0.0 2.0 1 1 1 2 2 2 0 Mif2/CENP-C like Smg4_UPF3 PF03467.10 CBZ55417.1 - 3.9e-25 88.8 0.0 6.7e-25 88.0 0.0 1.3 1 0 0 1 1 1 1 Smg-4/UPF3 family RRM_6 PF14259.1 CBZ55417.1 - 0.082 12.8 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CBZ55417.1 - 0.15 11.7 0.1 0.7 9.5 0.1 2.0 1 1 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AMA-1 PF02430.10 CBZ55418.1 - 1.5e-44 152.6 0.0 5.9e-34 117.7 0.0 2.3 2 0 0 2 2 2 2 Apical membrane antigen 1 DUF4366 PF14283.1 CBZ55418.1 - 0.0046 16.3 0.0 0.0074 15.7 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4366) SKG6 PF08693.5 CBZ55418.1 - 0.016 14.4 0.0 0.028 13.7 0.0 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain CD99L2 PF12301.3 CBZ55418.1 - 0.094 12.4 0.5 0.23 11.1 0.1 1.8 2 0 0 2 2 2 0 CD99 antigen like protein 2 AP2 PF00847.15 CBZ55420.1 - 1.2e-10 41.4 0.4 3.9e-10 39.7 0.3 2.0 1 0 0 1 1 1 1 AP2 domain DUF1268 PF06896.6 CBZ55420.1 - 3.6 7.9 0.0 6.5 7.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1268) EzrA PF06160.7 CBZ55420.1 - 6.6 4.7 0.2 13 3.8 0.1 1.3 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA p450 PF00067.17 CBZ55421.1 - 6.3e-37 127.1 0.0 9e-37 126.6 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 EF-hand_6 PF13405.1 CBZ55422.1 - 9.2e-09 34.4 0.3 0.0013 18.4 0.0 2.6 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.1 CBZ55422.1 - 2.8e-08 33.7 0.9 0.0048 17.0 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 CBZ55422.1 - 3.5e-08 32.1 0.2 0.0017 17.4 0.0 2.8 3 0 0 3 3 3 2 EF hand EF-hand_5 PF13202.1 CBZ55422.1 - 4.1e-05 22.7 5.3 0.029 13.7 0.7 2.9 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.1 CBZ55422.1 - 0.0035 16.9 0.1 2.9 7.5 0.0 3.3 2 2 2 4 4 4 1 EF-hand domain pair DUF3987 PF13148.1 CBZ55422.1 - 0.042 12.4 2.5 0.058 11.9 1.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) eIF3_subunit PF08597.5 CBZ55422.1 - 0.047 13.2 4.3 0.18 11.3 1.6 2.1 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit AIG2 PF06094.7 CBZ55423.1 - 0.21 12.0 1.3 0.97 9.9 0.9 2.2 1 0 0 1 1 1 0 AIG2-like family PolyA_pol PF01743.15 CBZ55424.1 - 1.5e-27 96.2 0.1 3.8e-27 95.0 0.0 1.7 1 0 0 1 1 1 1 Poly A polymerase head domain PTS_IIA PF02255.11 CBZ55424.1 - 0.036 13.9 0.0 0.14 12.0 0.0 2.0 1 0 0 1 1 1 0 PTS system, Lactose/Cellobiose specific IIA subunit Kinesin PF00225.18 CBZ55426.1 - 5.4e-47 160.1 0.3 2.1e-27 95.7 0.0 4.1 2 1 1 4 4 4 4 Kinesin motor domain DUF3638 PF12340.3 CBZ55427.1 - 3.6e-18 65.4 0.0 3.4e-17 62.2 0.0 2.5 3 0 0 3 3 3 1 Protein of unknown function (DUF3638) DUF3645 PF12359.3 CBZ55427.1 - 1.3e-15 56.1 0.1 3.8e-15 54.7 0.1 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF3645) EF-hand_6 PF13405.1 CBZ55427.1 - 3.4e-08 32.7 0.1 0.12 12.3 0.0 4.4 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.1 CBZ55427.1 - 6.3e-08 32.6 0.0 0.0011 19.0 0.0 2.9 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 CBZ55427.1 - 1.1e-05 24.3 0.2 0.1 11.9 0.0 2.8 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.1 CBZ55427.1 - 0.0012 18.4 0.1 0.087 12.4 0.0 3.0 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_9 PF14658.1 CBZ55427.1 - 0.097 12.5 0.0 4.9 7.1 0.0 2.6 2 0 0 2 2 2 0 EF-hand domain ResIII PF04851.10 CBZ55427.1 - 0.55 10.0 2.0 0.78 9.5 0.0 2.2 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit DUF4483 PF14825.1 CBZ55427.1 - 1.1 8.8 4.8 2.3 7.8 3.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4483) BAF1_ABF1 PF04684.8 CBZ55427.1 - 1.2 7.8 2.9 2.4 6.9 2.0 1.4 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Dockerin_1 PF00404.13 CBZ55427.1 - 1.3 8.8 0.6 3.2 7.6 0.4 1.8 1 0 0 1 1 1 0 Dockerin type I repeat EF-hand_5 PF13202.1 CBZ55427.1 - 1.7 8.0 2.6 1 8.8 0.0 2.0 2 0 0 2 2 2 0 EF hand Tim54 PF11711.3 CBZ55427.1 - 2 6.8 3.2 4.2 5.8 2.2 1.5 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 TFIIF_alpha PF05793.7 CBZ55427.1 - 2.2 6.5 14.3 4.8 5.4 9.9 1.4 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Utp14 PF04615.8 CBZ55427.1 - 4.6 5.2 14.1 8.2 4.4 9.8 1.3 1 0 0 1 1 1 0 Utp14 protein Ycf1 PF05758.7 CBZ55427.1 - 4.6 4.8 3.2 7.2 4.1 2.2 1.2 1 0 0 1 1 1 0 Ycf1 GlcNAc PF11397.3 CBZ55428.1 - 1.4e-28 99.9 0.5 2.1e-21 76.4 0.2 5.0 5 0 0 5 5 5 4 Glycosyltransferase (GlcNAc) RNA_pol_L_2 PF13656.1 CBZ55431.1 - 7.7e-17 60.5 0.0 1.1e-16 59.9 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.19 CBZ55431.1 - 0.0018 17.3 0.0 0.0026 16.8 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain DUF4345 PF14248.1 CBZ55432.1 - 0.0094 15.3 0.1 0.014 14.8 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4345) LMF1 PF06762.9 CBZ55433.1 - 1.3e-120 402.7 0.1 3.7e-117 391.3 0.0 2.8 2 1 0 2 2 2 2 Lipase maturation factor DUF674 PF05056.7 CBZ55433.1 - 0.037 12.6 0.0 0.054 12.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF674) zf-RING_2 PF13639.1 CBZ55434.1 - 9.4e-15 54.1 6.9 2.3e-14 52.9 4.8 1.7 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 CBZ55434.1 - 7.6e-08 31.9 6.1 7.6e-08 31.9 4.2 1.9 2 0 0 2 2 2 1 zinc-RING finger domain zf-rbx1 PF12678.2 CBZ55434.1 - 6.5e-07 29.3 3.4 1.8e-06 27.9 2.3 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 CBZ55434.1 - 1.6e-06 27.6 5.0 4e-06 26.3 3.5 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CBZ55434.1 - 1.7e-06 27.9 6.7 1.7e-06 27.9 4.7 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CBZ55434.1 - 3.8e-05 23.2 4.5 0.0001 21.9 3.1 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 CBZ55434.1 - 0.0063 16.2 1.6 0.0087 15.7 0.5 1.8 1 1 0 1 1 1 1 RING-type zinc-finger zf-Apc11 PF12861.2 CBZ55434.1 - 0.061 13.1 2.4 0.15 11.8 1.6 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-P11 PF03854.9 CBZ55434.1 - 0.098 12.1 3.3 0.047 13.1 0.5 1.7 2 0 0 2 2 2 0 P-11 zinc finger FANCL_C PF11793.3 CBZ55434.1 - 0.87 9.5 4.7 3.3 7.7 3.3 2.0 1 1 0 1 1 1 0 FANCL C-terminal domain Radical_SAM PF04055.16 CBZ55435.1 - 7.8e-16 58.6 0.0 1.3e-15 57.9 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily Wyosine_form PF08608.7 CBZ55435.1 - 2.9e-11 43.3 0.0 8.4e-11 41.8 0.0 1.9 1 0 0 1 1 1 1 Wyosine base formation Peptidase_C97 PF05903.9 CBZ55438.1 - 1.1e-24 86.9 0.0 1.6e-24 86.3 0.0 1.2 1 0 0 1 1 1 1 PPPDE putative peptidase domain LRAT PF04970.8 CBZ55438.1 - 0.15 11.9 0.1 0.26 11.2 0.1 1.3 1 0 0 1 1 1 0 Lecithin retinol acyltransferase Rpr2 PF04032.11 CBZ55439.1 - 0.001 18.8 0.0 0.0028 17.4 0.0 1.7 1 0 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain TGT PF01702.13 CBZ55440.1 - 4e-82 275.0 0.0 6.1e-82 274.4 0.0 1.3 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase Ribosomal_S15 PF00312.17 CBZ55441.1 - 6.7e-11 41.8 0.1 2.4e-10 40.0 0.1 1.9 1 0 0 1 1 1 1 Ribosomal protein S15 SDA1 PF05285.7 CBZ55441.1 - 0.0061 15.8 20.2 0.007 15.6 14.0 1.2 1 0 0 1 1 1 1 SDA1 Daxx PF03344.10 CBZ55441.1 - 0.82 8.0 31.4 1.1 7.7 21.8 1.1 1 0 0 1 1 1 0 Daxx Family CDC45 PF02724.9 CBZ55441.1 - 1.4 6.8 18.7 2.2 6.1 13.0 1.4 1 0 0 1 1 1 0 CDC45-like protein SAPS PF04499.10 CBZ55441.1 - 3.7 6.0 9.7 12 4.4 7.4 1.4 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein ORC6 PF05460.8 CBZ55441.1 - 5.4 6.0 12.0 8 5.4 8.3 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) MIP-T3 PF10243.4 CBZ55441.1 - 5.6 5.3 30.5 6.9 5.0 21.1 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Ycf1 PF05758.7 CBZ55441.1 - 9.2 3.8 11.2 11 3.5 7.8 1.2 1 0 0 1 1 1 0 Ycf1 GTP1_OBG PF01018.17 CBZ55442.1 - 2.4e-17 62.9 3.4 7.3e-06 25.7 1.9 3.7 3 0 0 3 3 3 3 GTP1/OBG MMR_HSR1 PF01926.18 CBZ55442.1 - 5.2e-17 61.8 0.0 1.1e-16 60.7 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 CBZ55442.1 - 2.8e-08 33.1 0.0 9.2e-08 31.5 0.0 1.8 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.18 CBZ55442.1 - 0.028 14.2 1.8 5.7 6.7 0.0 3.1 2 1 1 3 3 3 0 Dynamin family DGF-1_4 PF11024.3 CBZ55442.1 - 0.36 11.2 5.5 0.85 10.0 3.8 1.6 1 0 0 1 1 1 0 Dispersed gene family protein 1 of Trypanosoma cruzi region 4 Macoilin PF09726.4 CBZ55442.1 - 7 4.8 15.6 1.6 6.9 5.1 2.4 2 0 0 2 2 2 0 Transmembrane protein Romo1 PF10247.4 CBZ55444.1 - 7.4e-20 70.9 11.5 1.1e-19 70.3 7.9 1.3 1 0 0 1 1 1 1 Reactive mitochondrial oxygen species modulator 1 Pkinase PF00069.20 CBZ55445.1 - 7.8e-65 218.6 0.0 1.1e-64 218.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ55445.1 - 4.8e-42 143.8 0.0 7e-42 143.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CBZ55445.1 - 0.00056 19.7 0.2 0.099 12.3 0.0 2.6 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 CBZ55445.1 - 0.034 13.1 0.1 0.065 12.2 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.6 CBZ55445.1 - 0.35 9.5 0.0 0.52 9.0 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase FF PF01846.14 CBZ55447.1 - 1.2e-26 92.4 4.3 1.3e-10 41.0 0.1 5.8 5 0 0 5 5 5 4 FF domain WW PF00397.21 CBZ55447.1 - 0.0008 19.2 3.0 0.0017 18.1 2.1 1.6 1 0 0 1 1 1 1 WW domain rpo132 PF12415.3 CBZ55447.1 - 0.23 10.4 0.7 0.9 8.5 0.0 2.2 3 0 0 3 3 3 0 Poxvirus DNA dependent RNA polymerase Vpu PF00558.14 CBZ55447.1 - 7.8 6.1 6.3 74 3.0 4.6 2.5 2 0 0 2 2 2 0 Vpu protein Sod_Fe_C PF02777.13 CBZ55448.1 - 5.7e-38 128.9 0.7 5.7e-38 128.9 0.5 1.6 2 1 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 CBZ55448.1 - 7.9e-31 106.1 1.3 1.3e-30 105.4 0.9 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain His_Phos_1 PF00300.17 CBZ55449.1 - 1.4e-07 31.7 0.0 3.3e-05 24.0 0.0 2.7 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Med6 PF04934.9 CBZ55450.1 - 4.5e-16 58.6 0.0 8e-16 57.8 0.0 1.4 1 0 0 1 1 1 1 MED6 mediator sub complex component Syja_N PF02383.13 CBZ55451.1 - 1.6e-61 207.8 0.0 2e-61 207.5 0.0 1.1 1 0 0 1 1 1 1 SacI homology domain Dynactin_p62 PF05502.8 CBZ55452.1 - 1.2e-25 90.2 9.8 4.9e-14 51.9 6.8 3.4 3 0 0 3 3 3 3 Dynactin p62 family Prenyltrans PF00432.16 CBZ55455.1 - 5.9e-48 160.0 20.9 9.9e-10 37.8 0.0 6.2 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 CBZ55455.1 - 4e-38 130.2 0.1 4.9e-18 65.5 0.0 3.7 2 1 2 4 4 4 3 Prenyltransferase-like Prenyltrans_1 PF13243.1 CBZ55455.1 - 2e-10 40.6 0.0 0.0023 17.8 0.0 3.8 1 1 2 3 3 3 2 Prenyltransferase-like A2M_comp PF07678.9 CBZ55455.1 - 0.0016 17.7 0.0 0.98 8.5 0.0 3.4 3 1 0 3 3 3 1 A-macroglobulin complement component MFS_1 PF07690.11 CBZ55456.1 - 1.1e-30 106.5 40.7 4.6e-30 104.5 25.5 2.1 1 1 0 1 1 1 1 Major Facilitator Superfamily Helicase_C PF00271.26 CBZ55457.1 - 9.1e-19 67.1 0.0 1.9e-18 66.1 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 CBZ55457.1 - 1.1e-18 67.3 0.0 4.5e-18 65.3 0.0 2.0 1 1 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 CBZ55457.1 - 0.00038 20.3 0.0 0.00093 19.0 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Sod_Fe_C PF02777.13 CBZ55458.1 - 1.4e-41 140.6 0.6 3.4e-40 136.1 0.4 2.1 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 CBZ55458.1 - 1.9e-32 111.3 0.3 4.3e-32 110.2 0.2 1.6 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain ABC_tran PF00005.22 CBZ55459.1 - 9.9e-15 55.0 0.0 1.3e-14 54.6 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_30 PF13604.1 CBZ55459.1 - 0.00031 20.3 0.0 0.00045 19.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 CBZ55459.1 - 0.0022 17.1 0.0 0.0031 16.6 0.0 1.2 1 0 0 1 1 1 1 Zeta toxin AAA_17 PF13207.1 CBZ55459.1 - 0.008 16.9 0.2 0.013 16.2 0.1 1.6 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 CBZ55459.1 - 0.015 15.0 0.0 0.026 14.2 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain AAA_16 PF13191.1 CBZ55459.1 - 0.019 14.9 0.0 0.03 14.3 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain AAA_18 PF13238.1 CBZ55459.1 - 0.024 14.9 0.2 0.046 14.0 0.2 1.7 1 1 0 1 1 1 0 AAA domain NACHT PF05729.7 CBZ55459.1 - 0.055 13.1 0.1 0.087 12.4 0.1 1.3 1 0 0 1 1 1 0 NACHT domain T2SE PF00437.15 CBZ55459.1 - 0.088 11.6 0.1 0.14 11.0 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein NB-ARC PF00931.17 CBZ55459.1 - 0.097 11.5 0.2 0.15 10.9 0.1 1.2 1 0 0 1 1 1 0 NB-ARC domain DUF3584 PF12128.3 CBZ55459.1 - 0.1 9.8 0.1 0.13 9.5 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) AAA_21 PF13304.1 CBZ55459.1 - 0.13 12.1 0.0 0.17 11.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 CBZ55459.1 - 0.14 11.7 0.1 0.22 11.0 0.1 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain Viral_helicase1 PF01443.13 CBZ55459.1 - 0.16 11.4 0.2 0.25 10.8 0.1 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Sod_Fe_C PF02777.13 CBZ55460.1 - 3.9e-38 129.5 1.5 9.8e-38 128.2 0.7 1.8 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 CBZ55460.1 - 9.4e-32 109.1 0.4 1.7e-31 108.2 0.3 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain SURF6 PF04935.7 CBZ55462.1 - 8.1e-07 28.5 44.3 8.1e-07 28.5 30.7 2.1 3 0 0 3 3 3 1 Surfeit locus protein 6 DUF4303 PF14136.1 CBZ55462.1 - 0.12 11.9 1.5 0.69 9.5 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4303) DUF4252 PF14060.1 CBZ55462.1 - 3.9 7.0 9.6 1.7 8.2 4.7 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4252) Profilin PF00235.14 CBZ55463.1 - 0.0016 18.5 0.0 0.0024 17.9 0.0 1.2 1 0 0 1 1 1 1 Profilin Methyltransf_16 PF10294.4 CBZ55464.1 - 1.1e-14 54.2 0.1 1.7e-14 53.6 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase PCMT PF01135.14 CBZ55464.1 - 0.09 12.2 0.1 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Death PF00531.17 CBZ55465.1 - 0.0032 17.1 1.1 0.016 14.9 0.0 2.5 2 0 0 2 2 2 1 Death domain Tubulin PF00091.20 CBZ55466.1 - 3.4e-68 229.6 0.0 4.6e-68 229.2 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 CBZ55466.1 - 1.8e-51 173.4 0.3 7.6e-51 171.4 0.1 1.9 2 0 0 2 2 2 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 CBZ55466.1 - 0.027 13.9 0.0 0.11 12.0 0.0 2.0 2 0 0 2 2 2 0 Tubulin domain LRR_4 PF12799.2 CBZ55467.1 - 3.6e-22 77.5 2.3 2.3e-06 27.0 0.5 4.3 2 2 3 5 5 5 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CBZ55467.1 - 3.6e-14 52.2 1.8 3.6e-07 29.8 0.3 2.6 2 0 0 2 2 2 2 Leucine rich repeat LRR_6 PF13516.1 CBZ55467.1 - 3.5e-08 32.6 3.0 0.26 11.4 0.1 4.8 3 2 1 4 4 4 3 Leucine Rich repeat LRR_9 PF14580.1 CBZ55467.1 - 8.9e-07 28.6 0.6 0.0042 16.6 0.0 2.2 1 1 0 2 2 2 2 Leucine-rich repeat LRR_1 PF00560.28 CBZ55467.1 - 2.6e-06 26.6 10.1 0.37 10.9 0.0 5.3 4 2 1 5 5 5 2 Leucine Rich Repeat LRR_7 PF13504.1 CBZ55467.1 - 0.00038 20.1 9.0 4.5 7.9 0.1 5.9 5 2 1 6 6 6 2 Leucine rich repeat FAT PF02259.18 CBZ55468.1 - 1e-49 169.4 10.7 1.1e-21 77.2 0.3 4.6 4 0 0 4 4 4 4 FAT domain PI3_PI4_kinase PF00454.22 CBZ55468.1 - 3.8e-47 160.7 0.0 6.3e-47 160.0 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Rapamycin_bind PF08771.6 CBZ55468.1 - 4.5e-26 90.8 0.2 1.1e-25 89.6 0.1 1.7 1 0 0 1 1 1 1 Rapamycin binding domain FATC PF02260.15 CBZ55468.1 - 1.1e-12 47.1 1.2 1.7e-12 46.5 0.1 2.0 2 0 0 2 2 2 1 FATC domain TPR_16 PF13432.1 CBZ55468.1 - 2.1e-05 25.0 7.9 0.00059 20.4 0.5 4.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.1 CBZ55468.1 - 0.00013 21.4 6.4 0.0055 16.4 0.3 5.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.1 CBZ55468.1 - 0.00047 19.7 0.9 0.28 10.8 0.1 3.2 3 0 0 3 3 3 1 TPR repeat HEAT PF02985.17 CBZ55468.1 - 0.0013 18.6 6.5 5.3 7.3 0.2 5.1 3 0 0 3 3 3 1 HEAT repeat TPR_2 PF07719.12 CBZ55468.1 - 0.0077 16.0 1.4 3.8 7.6 0.0 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 CBZ55468.1 - 0.12 13.0 18.7 0.14 12.8 0.2 7.6 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_1 PF00515.23 CBZ55468.1 - 0.22 11.2 0.3 5.4 6.7 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.1 CBZ55468.1 - 1.5 9.2 10.0 0.097 13.0 0.1 3.8 4 0 0 4 4 3 0 Tetratricopeptide repeat TRAM_LAG1_CLN8 PF03798.11 CBZ55469.1 - 1.4e-28 99.7 21.6 3.1e-28 98.7 15.0 1.6 1 1 0 1 1 1 1 TLC domain XRN_N PF03159.13 CBZ55471.1 - 2.6e-31 108.8 0.0 8e-21 74.5 0.0 4.3 4 0 0 4 4 4 4 XRN 5'-3' exonuclease N-terminus DUF2040 PF09745.4 CBZ55472.1 - 9.5e-18 64.2 14.5 4.3e-15 55.6 5.1 4.6 4 1 1 5 5 5 2 Coiled-coil domain-containing protein 55 (DUF2040) CBM_48 PF02922.13 CBZ55474.1 - 9.6e-23 80.0 0.0 1e-20 73.5 0.0 3.1 3 0 0 3 3 3 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Alpha-amylase_C PF02806.13 CBZ55474.1 - 1.9e-19 69.5 0.0 7.5e-19 67.6 0.0 2.0 2 0 0 2 2 2 1 Alpha amylase, C-terminal all-beta domain Alpha-amylase PF00128.19 CBZ55474.1 - 7.3e-15 55.1 0.0 2.5e-08 33.7 0.0 3.1 1 1 1 3 3 3 2 Alpha amylase, catalytic domain Spc7 PF08317.6 CBZ55475.1 - 0.0028 16.3 6.1 0.0028 16.3 4.3 6.1 2 2 4 6 6 6 2 Spc7 kinetochore protein MAD PF05557.8 CBZ55475.1 - 0.39 8.7 95.7 0.034 12.2 55.1 4.1 1 1 1 2 2 2 0 Mitotic checkpoint protein DUF2460 PF09343.5 CBZ55476.1 - 0.1 11.9 0.2 0.17 11.2 0.1 1.5 1 1 0 1 1 1 0 Conserved hypothetical protein 2217 (DUF2460) PPR_3 PF13812.1 CBZ55479.1 - 0.041 14.1 0.0 0.53 10.6 0.0 2.6 2 0 0 2 2 2 0 Pentatricopeptide repeat domain PPR_2 PF13041.1 CBZ55479.1 - 0.1 12.5 0.0 0.54 10.2 0.0 2.0 1 1 1 2 2 2 0 PPR repeat family DUF2763 PF10961.3 CBZ55481.1 - 1.7e-08 34.7 1.3 1.7e-08 34.7 0.9 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF2763) FAST_1 PF06743.10 CBZ55482.1 - 0.027 14.1 13.1 4.2 7.1 0.3 5.9 4 1 1 5 5 5 0 FAST kinase-like protein, subdomain 1 WD40 PF00400.27 CBZ55483.1 - 3e-29 99.7 7.0 6e-06 25.9 0.0 6.8 6 0 0 6 6 6 5 WD domain, G-beta repeat eIF2A PF08662.6 CBZ55483.1 - 0.00015 21.5 0.0 0.29 10.8 0.0 2.3 2 0 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A zf-C3HC4 PF00097.20 CBZ55484.1 - 0.14 11.8 0.5 0.28 10.8 0.3 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prp19 PF08606.6 CBZ55485.1 - 0.92 9.2 9.4 3.9 7.2 1.7 3.4 2 1 1 3 3 3 0 Prp19/Pso4-like Seryl_tRNA_N PF02403.17 CBZ55485.1 - 1.3 9.0 14.8 2.9 7.9 4.2 2.8 2 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Bap31 PF05529.7 CBZ55485.1 - 2.2 7.6 8.7 0.4 10.1 1.7 2.4 2 0 0 2 2 2 0 B-cell receptor-associated protein 31-like Cullin PF00888.17 CBZ55486.1 - 2.1e-114 383.2 0.9 3.3e-114 382.5 0.6 1.2 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 CBZ55486.1 - 1.7e-26 91.8 1.2 4.1e-26 90.5 0.8 1.7 1 0 0 1 1 1 1 Cullin protein neddylation domain CopC PF04234.7 CBZ55486.1 - 0.22 12.1 1.7 29 5.3 0.0 3.2 3 0 0 3 3 3 0 CopC domain PseudoU_synth_2 PF00849.17 CBZ55488.1 - 1.8e-21 76.6 0.0 3.2e-21 75.8 0.0 1.4 1 0 0 1 1 1 1 RNA pseudouridylate synthase C2 PF00168.25 CBZ55490.1 - 7.7e-07 28.8 0.2 2.3e-05 24.1 0.2 2.5 1 1 0 1 1 1 1 C2 domain DUF553 PF04473.7 CBZ55490.1 - 0.09 12.0 0.0 0.17 11.1 0.0 1.4 1 0 0 1 1 1 0 Transglutaminase-like domain DEAD PF00270.24 CBZ55491.1 - 6.3e-16 58.3 0.0 1.2e-15 57.4 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase rRNA_proc-arch PF13234.1 CBZ55491.1 - 3.7e-08 32.8 0.0 0.0014 17.8 0.0 2.8 3 0 0 3 3 3 2 rRNA-processing arch domain Helicase_C PF00271.26 CBZ55491.1 - 0.0055 16.5 0.1 0.61 9.9 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Prenyltransf PF01255.14 CBZ55493.1 - 3.3e-24 85.2 0.0 4.4e-24 84.8 0.0 1.2 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase HTH_Tnp_Tc5 PF03221.11 CBZ55493.1 - 0.076 12.8 0.0 0.17 11.7 0.0 1.6 1 0 0 1 1 1 0 Tc5 transposase DNA-binding domain Sas10 PF09368.5 CBZ55494.1 - 9e-23 80.2 6.3 9e-23 80.2 4.4 2.8 2 0 0 2 2 2 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.10 CBZ55494.1 - 8.9e-18 64.2 2.4 9.1e-18 64.2 0.0 2.3 2 0 0 2 2 2 1 Sas10/Utp3/C1D family zf-C3HC4_3 PF13920.1 CBZ55496.1 - 4.4e-09 35.8 11.0 7.7e-09 35.0 7.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CBZ55496.1 - 1e-07 31.8 12.6 2e-07 30.9 8.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CBZ55496.1 - 4.1e-06 26.3 13.0 8.3e-06 25.3 9.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CBZ55496.1 - 6.3e-05 22.7 10.8 0.00012 21.8 7.5 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 CBZ55496.1 - 0.00041 20.0 13.1 0.00078 19.1 9.1 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_4 PF14570.1 CBZ55496.1 - 0.0016 17.9 9.2 0.0035 16.9 6.4 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.1 CBZ55496.1 - 0.0034 17.2 8.6 0.0094 15.8 6.0 1.8 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.2 CBZ55496.1 - 0.0065 16.5 4.4 0.018 15.1 3.1 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger DUF1104 PF06518.6 CBZ55496.1 - 0.0066 16.5 14.7 0.0069 16.4 3.4 4.1 2 1 1 3 3 3 1 Protein of unknown function (DUF1104) zf-RING_UBOX PF13445.1 CBZ55496.1 - 0.043 13.5 10.4 0.022 14.4 5.2 2.2 2 0 0 2 2 2 0 RING-type zinc-finger Prok-RING_4 PF14447.1 CBZ55496.1 - 0.064 12.8 5.2 0.16 11.5 3.6 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-UDP PF14569.1 CBZ55496.1 - 0.1 12.3 4.9 0.23 11.2 3.4 1.5 1 0 0 1 1 1 0 Zinc-binding RING-finger DZR PF12773.2 CBZ55496.1 - 1.8 8.4 7.0 6.2 6.7 4.9 1.9 1 0 0 1 1 1 0 Double zinc ribbon RdRP PF05183.7 CBZ55498.1 - 5.5e-108 362.1 0.0 2.4e-68 231.2 0.0 3.3 3 0 0 3 3 3 3 RNA dependent RNA polymerase Borrelia_P83 PF05262.6 CBZ55499.1 - 0.33 9.1 47.7 0.37 8.9 33.1 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein Mitofilin PF09731.4 CBZ55499.1 - 1.3 7.5 31.3 1.6 7.3 21.7 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein DER1 PF04511.10 CBZ55500.1 - 5.2e-40 137.0 14.6 5.9e-40 136.8 10.1 1.0 1 0 0 1 1 1 1 Der1-like family Rhomboid PF01694.17 CBZ55500.1 - 7.5e-06 26.0 16.3 1.2e-05 25.3 11.3 1.3 1 0 0 1 1 1 1 Rhomboid family MtrE PF04206.7 CBZ55500.1 - 0.25 10.3 4.4 0.54 9.2 0.1 2.2 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit E Myb_DNA-binding PF00249.26 CBZ55501.1 - 7.7e-10 38.6 0.1 9.1e-09 35.2 0.0 2.5 3 0 0 3 3 3 1 Myb-like DNA-binding domain ZZ PF00569.12 CBZ55501.1 - 3.1e-08 33.0 10.1 5.8e-08 32.1 7.0 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type Myb_DNA-bind_6 PF13921.1 CBZ55501.1 - 3.7e-06 26.9 0.2 7.7e-05 22.7 0.0 2.8 3 0 0 3 3 3 1 Myb-like DNA-binding domain DUF1674 PF07896.7 CBZ55503.1 - 5.7e-09 36.0 7.5 7.7e-09 35.6 3.8 2.4 2 1 0 2 2 2 1 Protein of unknown function (DUF1674) AFG1_ATPase PF03969.11 CBZ55504.1 - 2.7e-87 292.9 0.1 5.7e-85 285.2 0.1 2.9 2 1 0 2 2 2 1 AFG1-like ATPase AAA PF00004.24 CBZ55504.1 - 0.00013 22.1 0.0 0.0016 18.5 0.0 2.8 4 0 0 4 4 4 1 ATPase family associated with various cellular activities (AAA) Bac_DnaA PF00308.13 CBZ55504.1 - 0.00033 20.3 0.2 0.0014 18.2 0.0 2.0 2 0 0 2 2 2 1 Bacterial dnaA protein AAA_22 PF13401.1 CBZ55504.1 - 0.0043 17.1 0.1 0.3 11.2 0.1 3.2 2 1 0 2 2 2 1 AAA domain AAA_14 PF13173.1 CBZ55504.1 - 0.0097 15.8 0.1 0.029 14.2 0.0 1.8 2 0 0 2 2 2 1 AAA domain Arch_ATPase PF01637.13 CBZ55504.1 - 0.027 14.1 0.2 0.17 11.5 0.1 2.0 1 1 1 2 2 2 0 Archaeal ATPase NACHT PF05729.7 CBZ55504.1 - 0.049 13.2 0.0 0.21 11.2 0.0 2.0 2 0 0 2 2 2 0 NACHT domain DnaI_N PF07319.6 CBZ55504.1 - 0.054 13.7 0.6 0.38 11.0 0.1 2.2 2 0 0 2 2 2 0 Primosomal protein DnaI N-terminus TrwB_AAD_bind PF10412.4 CBZ55504.1 - 0.14 10.7 0.0 0.23 10.0 0.0 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_23 PF13476.1 CBZ55504.1 - 0.2 11.9 0.0 0.78 10.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain UvrD-helicase PF00580.16 CBZ55504.1 - 0.44 9.8 1.9 19 4.4 0.0 2.6 2 1 0 2 2 2 0 UvrD/REP helicase N-terminal domain GYF PF02213.11 CBZ55505.1 - 0.00059 19.3 0.3 0.0017 17.8 0.2 1.8 1 0 0 1 1 1 1 GYF domain LysM PF01476.15 CBZ55507.1 - 1.2e-06 28.3 0.0 2e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 LysM domain WD40 PF00400.27 CBZ55508.1 - 0.0056 16.5 0.0 33 4.5 0.0 3.6 4 0 0 4 4 4 3 WD domain, G-beta repeat DUF1900 PF08954.6 CBZ55509.1 - 1.9e-44 150.4 0.0 3.3e-44 149.7 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1900) WD40 PF00400.27 CBZ55509.1 - 2.3e-10 39.9 5.1 5e-05 23.0 0.1 3.0 3 0 0 3 3 3 2 WD domain, G-beta repeat DUF1899 PF08953.6 CBZ55509.1 - 3.5e-06 26.5 0.0 8e-06 25.4 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40_alt PF14077.1 CBZ55509.1 - 0.029 13.9 0.8 9.8 5.9 0.0 3.9 3 0 0 3 3 3 0 Alternative WD40 repeat motif IncA PF04156.9 CBZ55509.1 - 0.046 13.3 27.4 0.16 11.5 7.7 2.3 1 1 1 2 2 2 0 IncA protein NYD-SP28_assoc PF14775.1 CBZ55509.1 - 0.068 12.8 12.4 1.3 8.7 0.4 3.8 2 1 1 3 3 3 0 Sperm tail C-terminal domain GAS PF13851.1 CBZ55509.1 - 0.23 10.6 23.7 0.89 8.7 16.4 2.0 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding AAA_13 PF13166.1 CBZ55509.1 - 0.26 9.6 15.3 0.38 9.1 10.6 1.2 1 0 0 1 1 1 0 AAA domain TMCO5 PF14992.1 CBZ55509.1 - 0.28 10.2 14.1 0.44 9.6 9.8 1.3 1 0 0 1 1 1 0 TMCO5 family FUSC PF04632.7 CBZ55509.1 - 0.59 8.5 16.0 0.84 7.9 11.1 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF724 PF05266.9 CBZ55509.1 - 0.68 9.5 19.1 1.2 8.7 2.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF724) ATG16 PF08614.6 CBZ55509.1 - 0.77 9.5 25.4 0.64 9.8 6.3 2.3 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Osmo_CC PF08946.5 CBZ55509.1 - 0.82 9.7 4.8 1 9.4 0.4 2.4 2 0 0 2 2 2 0 Osmosensory transporter coiled coil Reo_sigmaC PF04582.7 CBZ55509.1 - 1.4 8.0 9.3 0.67 9.0 2.7 2.1 1 1 1 2 2 2 0 Reovirus sigma C capsid protein ADIP PF11559.3 CBZ55509.1 - 1.5 8.6 26.8 1.6 8.6 5.9 3.3 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding Occludin_ELL PF07303.8 CBZ55509.1 - 4 8.2 6.8 5.7 7.7 0.3 2.6 2 0 0 2 2 2 0 Occludin homology domain DUF1664 PF07889.7 CBZ55509.1 - 5.4 6.8 9.0 1.4 8.7 1.9 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Spc7 PF08317.6 CBZ55509.1 - 6.2 5.3 23.2 2.9 6.4 5.5 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein V_ATPase_I PF01496.14 CBZ55509.1 - 6.5 4.4 9.5 11 3.7 6.6 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family bZIP_1 PF00170.16 CBZ55509.1 - 7.1 6.6 30.7 0.57 10.1 2.5 4.9 2 2 3 5 5 5 0 bZIP transcription factor CDC37_N PF03234.9 CBZ55509.1 - 7.3 6.8 12.0 13 6.0 8.3 1.5 1 0 0 1 1 1 0 Cdc37 N terminal kinase binding Tropomyosin_1 PF12718.2 CBZ55509.1 - 7.8 6.3 30.9 0.23 11.3 3.6 2.7 1 1 1 2 2 2 0 Tropomyosin like FlaC_arch PF05377.6 CBZ55509.1 - 8.8 6.3 17.0 9.1 6.2 1.3 4.8 3 2 1 4 4 4 0 Flagella accessory protein C (FlaC) TSC22 PF01166.13 CBZ55509.1 - 9 6.3 14.8 33 4.5 0.7 4.4 2 1 1 4 4 4 0 TSC-22/dip/bun family DUF342 PF03961.8 CBZ55509.1 - 9.8 4.4 14.9 0.5 8.7 4.7 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF342) LRR_4 PF12799.2 CBZ55510.1 - 1.4e-09 37.3 20.1 2.1e-06 27.1 2.9 3.2 2 1 3 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CBZ55510.1 - 3.4e-06 26.7 8.8 1.4e-05 24.7 3.0 2.6 1 1 1 2 2 2 2 Leucine rich repeat LRR_1 PF00560.28 CBZ55510.1 - 0.00061 19.4 7.8 0.27 11.3 1.7 3.4 2 1 0 2 2 2 2 Leucine Rich Repeat LRR_6 PF13516.1 CBZ55510.1 - 0.0033 17.3 6.3 1.4 9.2 0.0 3.3 2 1 1 3 3 3 2 Leucine Rich repeat LRR_9 PF14580.1 CBZ55510.1 - 0.015 14.8 0.1 0.045 13.2 0.1 1.7 1 1 0 1 1 1 0 Leucine-rich repeat LRR_7 PF13504.1 CBZ55510.1 - 0.017 15.2 8.7 1.3 9.5 1.3 3.8 3 1 0 3 3 3 0 Leucine rich repeat GTP_EFTU PF00009.22 CBZ55511.1 - 3.8e-31 107.9 0.0 1.4e-30 106.1 0.0 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.20 CBZ55511.1 - 5.2e-09 36.1 1.4 1e-08 35.1 0.9 1.5 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 CBZ55511.1 - 1e-06 28.6 0.0 3.7e-05 23.6 0.0 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 CBZ55511.1 - 0.0025 17.0 0.0 0.23 10.6 0.0 2.2 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit cobW PF02492.14 CBZ55511.1 - 0.0038 16.6 0.9 0.059 12.8 0.1 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.4 CBZ55511.1 - 0.006 16.0 0.2 0.86 9.0 0.1 2.4 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation GTP_EFTU_D4 PF14578.1 CBZ55511.1 - 0.0076 15.8 0.1 0.018 14.7 0.1 1.5 1 0 0 1 1 1 1 Elongation factor Tu domain 4 Miro PF08477.8 CBZ55511.1 - 0.034 14.6 0.0 2.4 8.6 0.0 2.4 2 0 0 2 2 2 0 Miro-like protein CbiA PF01656.18 CBZ55511.1 - 0.1 11.9 0.1 0.25 10.7 0.0 1.6 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain HA2 PF04408.18 CBZ55512.1 - 8.5e-23 80.3 0.1 1.6e-22 79.4 0.1 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 CBZ55512.1 - 2.1e-11 43.4 0.0 6.1e-11 42.0 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 CBZ55512.1 - 2.7e-08 33.5 0.0 5.6e-08 32.4 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase OB_NTP_bind PF07717.11 CBZ55512.1 - 9.4e-07 28.6 0.1 5e-06 26.3 0.0 2.0 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_22 PF13401.1 CBZ55512.1 - 5.2e-06 26.6 0.3 2e-05 24.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain T2SE PF00437.15 CBZ55512.1 - 9.1e-05 21.4 0.1 0.00016 20.6 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_16 PF13191.1 CBZ55512.1 - 0.0041 17.1 0.3 0.025 14.5 0.1 2.5 1 1 1 2 2 2 1 AAA ATPase domain AAA_19 PF13245.1 CBZ55512.1 - 0.005 16.5 0.4 0.014 15.0 0.3 1.8 1 0 0 1 1 1 1 Part of AAA domain KaiC PF06745.8 CBZ55512.1 - 0.005 15.9 0.0 0.0092 15.1 0.0 1.3 1 0 0 1 1 1 1 KaiC AAA_23 PF13476.1 CBZ55512.1 - 0.0053 17.1 0.1 0.057 13.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 CBZ55512.1 - 0.0059 16.0 0.1 0.017 14.5 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 CBZ55512.1 - 0.0081 15.6 0.0 0.019 14.4 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain ResIII PF04851.10 CBZ55512.1 - 0.012 15.4 0.0 0.075 12.8 0.0 2.0 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_30 PF13604.1 CBZ55512.1 - 0.013 15.0 0.0 0.032 13.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain Herpes_ori_bp PF02399.10 CBZ55512.1 - 0.039 11.9 0.0 0.062 11.2 0.0 1.2 1 0 0 1 1 1 0 Origin of replication binding protein AAA_11 PF13086.1 CBZ55512.1 - 0.042 13.4 0.0 0.09 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 CBZ55512.1 - 0.043 14.1 0.0 0.57 10.4 0.0 2.4 2 0 0 2 2 2 0 ABC transporter Flavi_DEAD PF07652.9 CBZ55512.1 - 0.068 12.9 0.1 0.44 10.3 0.1 2.1 1 1 0 1 1 1 0 Flavivirus DEAD domain DUF2487 PF10673.4 CBZ55512.1 - 0.087 12.6 0.3 4.2 7.1 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2487) CTP_transf_2 PF01467.21 CBZ55513.1 - 3.4e-19 69.4 0.2 7.2e-19 68.3 0.1 1.6 1 1 0 1 1 1 1 Cytidylyltransferase CIAPIN1 PF05093.8 CBZ55516.1 - 8e-23 80.4 15.5 1.1e-21 76.8 10.8 2.2 1 1 0 1 1 1 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis Methyltransf_18 PF12847.2 CBZ55516.1 - 0.001 19.5 0.0 0.0019 18.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain DUF4191 PF13829.1 CBZ55516.1 - 0.074 12.1 0.1 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) GpcrRhopsn4 PF10192.4 CBZ55517.1 - 1.3e-07 31.0 2.9 1.3e-07 31.0 2.0 1.3 1 1 0 1 1 1 1 Rhodopsin-like GPCR transmembrane domain Lung_7-TM_R PF06814.8 CBZ55517.1 - 4.4e-07 29.1 13.2 6.4e-07 28.6 9.2 1.1 1 0 0 1 1 1 1 Lung seven transmembrane receptor DUF1673 PF07895.6 CBZ55517.1 - 0.17 11.4 4.4 0.42 10.1 3.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1673) WD40 PF00400.27 CBZ55518.1 - 3.9e-57 188.2 32.1 1.3e-14 53.4 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 CBZ55518.1 - 8.1e-06 25.6 1.2 0.12 12.0 0.0 3.0 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A VEFS-Box PF09733.4 CBZ55518.1 - 0.064 12.9 0.1 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 VEFS-Box of polycomb protein DUF1227 PF06777.6 CBZ55519.1 - 9.1e-48 161.6 1.4 9.2e-43 145.4 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1227) DEAD_2 PF06733.10 CBZ55519.1 - 4e-30 104.5 0.0 1.4e-16 60.3 0.0 4.2 3 1 0 3 3 3 3 DEAD_2 Helicase_C_2 PF13307.1 CBZ55519.1 - 2e-25 89.6 0.1 4.6e-25 88.5 0.0 1.6 1 0 0 1 1 1 1 Helicase C-terminal domain ResIII PF04851.10 CBZ55519.1 - 1.6e-05 24.7 0.4 0.00086 19.1 0.0 2.6 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit SPX PF03105.14 CBZ55519.1 - 0.0062 16.3 7.5 0.0062 16.3 5.2 1.6 2 0 0 2 2 2 1 SPX domain DEAD PF00270.24 CBZ55519.1 - 0.0093 15.4 0.1 0.25 10.8 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase DUF572 PF04502.8 CBZ55519.1 - 0.036 13.3 16.8 0.084 12.0 11.7 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF572) Macoilin PF09726.4 CBZ55519.1 - 0.13 10.5 20.6 0.2 9.8 14.3 1.2 1 0 0 1 1 1 0 Transmembrane protein Pol_alpha_B_N PF08418.5 CBZ55519.1 - 0.13 11.8 12.9 0.67 9.4 8.5 2.3 2 0 0 2 2 2 0 DNA polymerase alpha subunit B N-terminal AAA_22 PF13401.1 CBZ55519.1 - 0.15 12.1 0.0 14 5.7 0.0 2.9 2 0 0 2 2 2 0 AAA domain Herpes_pp85 PF04637.7 CBZ55519.1 - 0.95 7.6 2.7 1.6 6.9 1.9 1.4 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) DUF4482 PF14818.1 CBZ55519.1 - 1.3 9.6 10.8 0.81 10.3 5.5 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4482) Herpes_capsid PF06112.6 CBZ55519.1 - 2 8.4 43.4 0.055 13.5 24.9 2.2 2 0 0 2 2 2 0 Gammaherpesvirus capsid protein CDC45 PF02724.9 CBZ55519.1 - 2.3 6.1 11.6 3.6 5.5 8.0 1.2 1 0 0 1 1 1 0 CDC45-like protein Vfa1 PF08432.5 CBZ55519.1 - 5.5 6.9 8.3 10 6.1 4.1 2.2 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 DNA_pol_viral_N PF00242.12 CBZ55519.1 - 5.8 5.8 21.1 10 4.9 14.7 1.3 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain Paf1 PF03985.8 CBZ55519.1 - 9.7 4.8 9.8 16 4.0 6.8 1.2 1 0 0 1 1 1 0 Paf1 DEAD PF00270.24 CBZ55520.1 - 2.6e-35 121.3 0.2 4.4e-35 120.6 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CBZ55520.1 - 2.3e-26 91.4 0.2 2.7e-25 88.0 0.1 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.10 CBZ55520.1 - 0.00069 19.5 0.1 0.0017 18.1 0.1 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.1 CBZ55520.1 - 0.0091 15.0 0.1 0.017 14.1 0.0 1.4 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit ThuA PF06283.6 CBZ55520.1 - 0.15 11.7 0.0 0.3 10.7 0.0 1.4 1 0 0 1 1 1 0 Trehalose utilisation Stn1 PF10451.4 CBZ55521.1 - 0.071 11.9 0.0 0.12 11.1 0.0 1.3 1 0 0 1 1 1 0 Telomere regulation protein Stn1 IBD PF10416.4 CBZ55522.1 - 0.079 12.7 0.3 0.17 11.6 0.2 1.5 1 0 0 1 1 1 0 Transcription-initiator DNA-binding domain IBD DUF612 PF04747.7 CBZ55522.1 - 2.5 6.9 9.0 4.5 6.0 6.3 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF612 DDHD PF02862.12 CBZ55522.1 - 3.9 7.1 9.9 7.4 6.2 3.0 2.4 2 0 0 2 2 2 0 DDHD domain DTW PF03942.10 CBZ55523.1 - 1.1e-18 67.1 0.0 3.5e-18 65.5 0.0 1.8 1 1 0 1 1 1 1 DTW domain MFS_1 PF07690.11 CBZ55524.1 - 2.5e-32 111.9 22.9 2.5e-32 111.9 15.9 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 CBZ55524.1 - 1.6e-06 27.0 19.1 1.3e-05 23.9 13.2 2.6 1 1 0 1 1 1 1 Sugar (and other) transporter OATP PF03137.15 CBZ55524.1 - 0.00021 19.4 0.0 0.14 10.1 0.0 2.6 2 1 0 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family MFS_1_like PF12832.2 CBZ55524.1 - 0.01 15.5 0.1 1.2 9.0 0.0 3.4 3 0 0 3 3 3 0 MFS_1 like family DUF3094 PF11293.3 CBZ55524.1 - 0.28 10.6 2.4 0.3 10.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3094) 5_nucleotid_C PF02872.13 CBZ55525.1 - 4e-28 98.3 0.0 7.4e-28 97.4 0.0 1.5 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.23 CBZ55525.1 - 8.8e-07 28.5 0.2 3.7e-06 26.4 0.1 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 CBZ55525.1 - 3.2e-05 23.8 0.0 0.004 16.9 0.0 2.4 2 1 0 2 2 2 2 Calcineurin-like phosphoesterase superfamily domain ABC_tran PF00005.22 CBZ55526.1 - 3.6e-36 124.4 0.0 6.4e-17 62.1 0.0 2.5 2 1 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 CBZ55526.1 - 2e-14 54.2 2.2 0.006 16.5 0.0 4.3 2 2 2 4 4 4 4 AAA domain RLI PF04068.10 CBZ55526.1 - 2e-14 52.8 8.9 3e-14 52.2 4.2 2.5 2 0 0 2 2 2 1 Possible Fer4-like domain in RNase L inhibitor, RLI SMC_N PF02463.14 CBZ55526.1 - 6.2e-11 41.9 3.0 0.0016 17.6 0.0 3.8 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_15 PF13175.1 CBZ55526.1 - 2e-08 33.6 0.0 0.14 11.1 0.0 4.0 4 0 0 4 4 4 3 AAA ATPase domain AAA_29 PF13555.1 CBZ55526.1 - 1.2e-07 31.1 0.0 0.02 14.4 0.0 2.4 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.1 CBZ55526.1 - 6.3e-07 29.5 0.0 0.00066 19.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain Fer4 PF00037.22 CBZ55526.1 - 1.9e-06 27.1 4.2 1.9e-06 27.1 2.9 2.2 2 0 0 2 2 1 1 4Fe-4S binding domain DUF258 PF03193.11 CBZ55526.1 - 9.4e-06 24.8 2.0 0.013 14.6 0.0 3.0 3 0 0 3 3 3 2 Protein of unknown function, DUF258 Fer4_6 PF12837.2 CBZ55526.1 - 1.3e-05 24.8 12.1 4.9e-05 23.0 2.0 2.4 2 0 0 2 2 2 1 4Fe-4S binding domain AAA_16 PF13191.1 CBZ55526.1 - 1.3e-05 25.2 0.0 0.0069 16.3 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_17 PF13207.1 CBZ55526.1 - 3.7e-05 24.5 0.0 0.52 11.1 0.0 3.0 2 1 0 2 2 2 2 AAA domain AAA_18 PF13238.1 CBZ55526.1 - 8.9e-05 22.7 0.0 0.099 12.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 CBZ55526.1 - 0.00013 21.7 0.1 0.034 13.8 0.0 2.7 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) NACHT PF05729.7 CBZ55526.1 - 0.00018 21.2 0.1 0.087 12.4 0.0 2.5 2 0 0 2 2 2 1 NACHT domain Rad17 PF03215.10 CBZ55526.1 - 0.00027 19.7 0.0 0.017 13.8 0.0 2.2 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein MobB PF03205.9 CBZ55526.1 - 0.00031 20.4 0.2 0.14 11.8 0.0 2.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA PF00004.24 CBZ55526.1 - 0.0006 20.0 0.0 0.65 10.2 0.0 2.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 CBZ55526.1 - 0.00085 19.2 0.0 0.085 12.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 CBZ55526.1 - 0.0012 18.7 0.0 0.099 12.6 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase Miro PF08477.8 CBZ55526.1 - 0.0018 18.7 0.0 0.066 13.7 0.0 2.5 2 0 0 2 2 2 1 Miro-like protein RNA_helicase PF00910.17 CBZ55526.1 - 0.002 18.2 0.0 3.5 7.8 0.0 2.6 2 0 0 2 2 2 0 RNA helicase Fer4_2 PF12797.2 CBZ55526.1 - 0.002 17.9 2.7 0.002 17.9 1.9 2.6 2 0 0 2 2 2 1 4Fe-4S binding domain Fer4_7 PF12838.2 CBZ55526.1 - 0.0027 18.0 2.0 0.0027 18.0 1.4 2.3 1 1 2 3 3 3 1 4Fe-4S dicluster domain AAA_25 PF13481.1 CBZ55526.1 - 0.003 16.9 0.0 3.6 6.9 0.0 2.7 3 0 0 3 3 2 0 AAA domain Fer4_21 PF14697.1 CBZ55526.1 - 0.0037 17.0 11.2 0.0075 16.1 7.7 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain AAA_23 PF13476.1 CBZ55526.1 - 0.0039 17.5 0.0 0.53 10.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain SRP54 PF00448.17 CBZ55526.1 - 0.0063 15.9 0.9 1.7 8.0 0.0 2.3 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain SbcCD_C PF13558.1 CBZ55526.1 - 0.0087 15.9 0.0 5.7 6.9 0.0 3.3 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Fer4_10 PF13237.1 CBZ55526.1 - 0.0092 15.7 1.5 0.0092 15.7 1.1 1.8 1 1 1 2 2 2 2 4Fe-4S dicluster domain VirE PF05272.6 CBZ55526.1 - 0.013 15.0 0.0 2.8 7.3 0.0 2.5 2 0 0 2 2 2 0 Virulence-associated protein E Fer4_3 PF12798.2 CBZ55526.1 - 0.016 15.7 4.3 0.016 15.7 3.0 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain AAA_28 PF13521.1 CBZ55526.1 - 0.016 15.1 0.1 3 7.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.1 CBZ55526.1 - 0.017 14.9 0.2 4.1 7.3 0.0 3.3 3 1 0 3 3 2 0 AAA domain Fer4_9 PF13187.1 CBZ55526.1 - 0.02 15.1 12.1 0.072 13.3 8.3 2.0 1 1 0 1 1 1 0 4Fe-4S dicluster domain DUF815 PF05673.8 CBZ55526.1 - 0.026 13.4 0.2 1.5 7.7 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Thymidylate_kin PF02223.12 CBZ55526.1 - 0.026 13.8 0.0 2.3 7.5 0.0 2.5 2 0 0 2 2 2 0 Thymidylate kinase Mg_chelatase PF01078.16 CBZ55526.1 - 0.028 13.5 0.2 0.12 11.5 0.0 2.0 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Fer4_16 PF13484.1 CBZ55526.1 - 0.046 14.4 1.0 0.046 14.4 0.7 2.3 2 0 0 2 2 2 0 4Fe-4S double cluster binding domain ArgK PF03308.11 CBZ55526.1 - 0.048 12.4 0.4 1.2 7.9 0.1 2.1 2 0 0 2 2 2 0 ArgK protein UPF0079 PF02367.12 CBZ55526.1 - 0.059 13.0 0.0 1.6 8.3 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_30 PF13604.1 CBZ55526.1 - 0.062 12.8 0.0 2.9 7.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.10 CBZ55526.1 - 0.11 12.1 0.4 17 5.0 0.1 2.5 2 0 0 2 2 2 0 NTPase AAA_13 PF13166.1 CBZ55526.1 - 0.13 10.7 0.6 0.32 9.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 CBZ55526.1 - 0.18 11.1 1.8 6.4 6.1 0.0 2.8 3 0 0 3 3 3 0 AAA-like domain Fer4_8 PF13183.1 CBZ55526.1 - 0.18 11.8 9.2 0.16 12.0 1.0 1.9 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_4 PF12800.2 CBZ55526.1 - 3 8.4 14.1 0.12 12.8 1.9 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_18 PF13746.1 CBZ55526.1 - 8.2 6.9 10.6 31 5.0 6.9 2.1 1 1 0 1 1 1 0 4Fe-4S dicluster domain HUN PF08729.5 CBZ55527.1 - 0.021 14.6 1.1 0.049 13.5 0.8 1.5 1 0 0 1 1 1 0 HPC2 and ubinuclein domain PseudoU_synth_2 PF00849.17 CBZ55528.1 - 4.5e-08 33.0 0.0 1e-07 31.9 0.0 1.7 1 0 0 1 1 1 1 RNA pseudouridylate synthase Cupin_3 PF05899.7 CBZ55528.1 - 0.028 13.8 0.0 0.062 12.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF861) Leo1 PF04004.8 CBZ55529.1 - 2.5e-21 76.1 1.0 2.5e-21 76.1 0.7 1.9 2 0 0 2 2 2 1 Leo1-like protein Flavokinase PF01687.12 CBZ55530.1 - 3.2e-27 94.8 0.0 1.5e-19 70.1 0.0 2.3 2 0 0 2 2 2 2 Riboflavin kinase MCM PF00493.18 CBZ55531.1 - 5.2e-106 354.1 0.0 1.6e-94 316.3 0.0 2.2 2 0 0 2 2 2 2 MCM2/3/5 family Mg_chelatase PF01078.16 CBZ55531.1 - 1.2e-06 27.8 0.0 0.0004 19.6 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI MCM_N PF14551.1 CBZ55531.1 - 5.9e-06 26.7 0.0 3.2e-05 24.3 0.0 2.3 3 0 0 3 3 3 1 MCM N-terminal domain AAA_3 PF07726.6 CBZ55531.1 - 0.0036 16.8 0.0 0.0076 15.8 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 CBZ55531.1 - 0.031 13.9 0.0 0.082 12.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA PF00004.24 CBZ55531.1 - 0.091 12.9 0.0 0.2 11.8 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) MFS_1 PF07690.11 CBZ55532.1 - 8.6e-11 41.1 25.3 3.3e-07 29.3 6.6 2.4 3 0 0 3 3 3 2 Major Facilitator Superfamily Pep_deformylase PF01327.16 CBZ55533.1 - 2e-43 147.5 0.0 2.5e-43 147.2 0.0 1.1 1 0 0 1 1 1 1 Polypeptide deformylase Ank_2 PF12796.2 CBZ55534.1 - 5.7e-41 138.7 8.1 7.9e-13 48.5 0.3 4.2 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.1 CBZ55534.1 - 1.9e-35 120.6 8.6 2.8e-11 43.6 0.1 5.6 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.25 CBZ55534.1 - 9.1e-35 116.7 6.8 5.5e-09 35.3 0.3 7.3 7 0 0 7 7 7 5 Ankyrin repeat Ank_5 PF13857.1 CBZ55534.1 - 2.3e-34 116.6 5.1 2.6e-08 33.8 0.0 5.6 3 1 3 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 CBZ55534.1 - 3.7e-32 107.1 2.0 1.4e-05 24.8 0.1 7.3 7 0 0 7 7 7 7 Ankyrin repeat DUF2226 PF09987.4 CBZ55534.1 - 0.028 13.5 0.0 0.077 12.1 0.0 1.8 1 1 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2226) Anoctamin PF04547.7 CBZ55534.1 - 0.04 12.5 0.1 0.59 8.7 0.0 2.0 2 0 0 2 2 2 0 Calcium-activated chloride channel DUF912 PF06024.7 CBZ55534.1 - 0.15 12.1 2.8 0.23 11.5 0.0 2.4 3 0 0 3 3 3 0 Nucleopolyhedrovirus protein of unknown function (DUF912) VIT1 PF01988.14 CBZ55534.1 - 0.26 10.7 3.4 0.76 9.2 2.4 1.8 1 1 0 1 1 1 0 VIT family KH_1 PF00013.24 CBZ55535.1 - 2.9e-25 87.6 9.2 5.8e-11 41.8 2.3 6.1 6 0 0 6 6 6 3 KH domain KH_3 PF13014.1 CBZ55535.1 - 1.5e-12 46.8 2.4 0.0013 18.3 0.9 4.9 4 0 0 4 4 4 3 KH domain KH_2 PF07650.12 CBZ55535.1 - 0.0029 17.1 9.9 0.18 11.4 0.1 3.4 3 0 0 3 3 3 2 KH domain KH_4 PF13083.1 CBZ55535.1 - 0.0042 16.7 0.2 0.7 9.5 0.0 3.0 2 0 0 2 2 2 1 KH domain BMC PF00936.14 CBZ55535.1 - 0.017 14.7 4.6 1.1 9.0 0.7 3.8 4 0 0 4 4 4 0 BMC domain SLS PF14611.1 CBZ55535.1 - 0.02 14.3 0.0 8.8 5.6 0.0 3.8 3 1 0 4 4 4 0 Mitochondrial inner-membrane-bound regulator HMA PF00403.21 CBZ55535.1 - 0.11 12.6 3.6 0.32 11.1 0.1 3.4 4 0 0 4 4 4 0 Heavy-metal-associated domain KTI12 PF08433.5 CBZ55535.1 - 1.8 7.7 6.2 0.16 11.1 0.5 1.9 2 0 0 2 2 2 0 Chromatin associated protein KTI12 GHMP_kinases_C PF08544.8 CBZ55538.1 - 1.7e-09 37.7 0.7 6.9e-09 35.7 0.1 2.3 2 0 0 2 2 2 1 GHMP kinases C terminal GHMP_kinases_N PF00288.21 CBZ55538.1 - 0.00054 19.9 1.7 0.00054 19.9 1.2 3.5 2 1 0 2 2 2 1 GHMP kinases N terminal domain SymE_toxin PF08845.5 CBZ55538.1 - 0.16 11.8 0.0 0.36 10.7 0.0 1.6 1 0 0 1 1 1 0 Toxin SymE, type I toxin-antitoxin system Trigger_C PF05698.9 CBZ55539.1 - 1e-10 41.7 4.6 2.1e-10 40.6 3.2 1.5 1 0 0 1 1 1 1 Bacterial trigger factor protein (TF) C-terminus Trigger_N PF05697.8 CBZ55539.1 - 8.9e-10 38.5 0.0 2.3e-09 37.2 0.0 1.6 1 0 0 1 1 1 1 Bacterial trigger factor protein (TF) DUF648 PF04890.8 CBZ55539.1 - 0.019 14.1 0.1 0.036 13.2 0.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF648) DUF2201_N PF13203.1 CBZ55539.1 - 0.098 11.8 7.3 0.18 10.9 5.1 1.4 1 0 0 1 1 1 0 Putative metallopeptidase domain EF-hand_7 PF13499.1 CBZ55540.1 - 2.9e-05 24.1 0.5 0.68 10.1 0.1 3.6 3 0 0 3 3 3 2 EF-hand domain pair He_PIG PF05345.7 CBZ55540.1 - 0.0018 18.2 1.5 0.0037 17.2 0.0 2.3 3 0 0 3 3 3 1 Putative Ig domain EF-hand_8 PF13833.1 CBZ55540.1 - 0.0019 17.7 3.3 1 9.0 0.5 4.3 4 0 0 4 4 4 2 EF-hand domain pair EF-hand_1 PF00036.27 CBZ55540.1 - 0.0097 15.1 1.9 0.5 9.7 0.2 3.2 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.1 CBZ55540.1 - 0.011 15.5 3.4 2.6 8.1 0.1 3.8 3 0 0 3 3 3 0 EF-hand domain DUF912 PF06024.7 CBZ55540.1 - 1.2 9.2 3.2 36 4.4 0.5 2.8 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) FtsJ PF01728.14 CBZ55541.1 - 6.4e-18 65.3 0.0 1.1e-17 64.5 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase Cytochrom_B558a PF05038.8 CBZ55541.1 - 0.031 13.8 1.9 9.4 5.8 0.0 3.2 3 0 0 3 3 3 0 Cytochrome Cytochrome b558 alpha-subunit SNF PF00209.13 CBZ55541.1 - 0.091 11.2 0.0 0.14 10.6 0.0 1.1 1 0 0 1 1 1 0 Sodium:neurotransmitter symporter family Exo_endo_phos PF03372.18 CBZ55542.1 - 1.6e-15 57.7 0.0 6.3e-15 55.7 0.0 1.8 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family HEAT PF02985.17 CBZ55543.1 - 6.8e-24 81.7 21.3 8.9e-05 22.2 0.1 11.9 11 0 0 11 11 11 7 HEAT repeat HEAT_EZ PF13513.1 CBZ55543.1 - 2.3e-22 78.8 26.3 2.7e-10 40.4 0.1 11.2 10 2 2 12 12 12 5 HEAT-like repeat HEAT_2 PF13646.1 CBZ55543.1 - 4.7e-20 71.6 5.2 1.2e-05 25.4 0.1 8.0 4 4 3 7 7 7 5 HEAT repeats Cnd1 PF12717.2 CBZ55543.1 - 2.4e-12 47.0 0.0 6.3e-06 26.1 0.0 4.4 4 0 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 Arm PF00514.18 CBZ55543.1 - 6.2e-08 32.1 8.4 0.092 12.6 0.1 7.2 8 0 0 8 8 8 2 Armadillo/beta-catenin-like repeat Vac14_Fab1_bd PF12755.2 CBZ55543.1 - 4.3e-06 27.0 0.1 2.3 8.6 0.0 4.8 4 1 1 5 5 5 2 Vacuolar 14 Fab1-binding region CLASP_N PF12348.3 CBZ55543.1 - 1.2e-05 24.8 0.9 1.8 7.8 0.0 5.3 3 3 1 4 4 4 2 CLASP N terminal IBN_N PF03810.14 CBZ55543.1 - 1.4e-05 24.9 0.2 0.00018 21.3 0.0 3.0 3 0 0 3 3 3 1 Importin-beta N-terminal domain Adaptin_N PF01602.15 CBZ55543.1 - 0.00049 18.5 0.2 0.27 9.4 0.2 3.5 3 1 0 3 3 3 2 Adaptin N terminal region DUF2454 PF10521.4 CBZ55543.1 - 0.013 14.5 0.1 0.27 10.2 0.0 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF2454) HEAT_PBS PF03130.11 CBZ55543.1 - 0.59 10.7 6.2 5.3 7.8 0.1 5.4 5 0 0 5 5 5 0 PBS lyase HEAT-like repeat MMS19_C PF12460.3 CBZ55543.1 - 4.3 5.9 7.0 16 4.0 0.0 4.5 5 1 1 6 6 6 0 RNAPII transcription regulator C-terminal Methyltransf_8 PF05148.10 CBZ55545.1 - 1.2e-53 182.0 0.0 7.8e-33 113.9 0.0 3.1 2 1 1 3 3 3 2 Hypothetical methyltransferase Methyltransf_11 PF08241.7 CBZ55545.1 - 8.5e-06 26.1 0.0 5.2e-05 23.6 0.0 2.4 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_23 PF13489.1 CBZ55545.1 - 0.11 12.2 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.13 CBZ55545.1 - 0.19 10.8 0.0 0.29 10.2 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.7 CBZ55545.1 - 0.19 12.2 0.2 0.65 10.5 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain Glycos_transf_2 PF00535.21 CBZ55546.1 - 8.6e-16 58.0 0.0 5.7e-08 32.6 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferase family 2 Glyco_tranf_2_4 PF13704.1 CBZ55546.1 - 0.13 12.5 0.0 0.56 10.5 0.0 1.9 2 0 0 2 2 2 0 Glycosyl transferase family 2 RRF PF01765.14 CBZ55547.1 - 1.1e-28 99.7 0.5 2e-28 98.9 0.3 1.4 1 0 0 1 1 1 1 Ribosome recycling factor Thioredoxin PF00085.15 CBZ55548.1 - 0.00048 19.7 0.0 0.00099 18.7 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin DDHD PF02862.12 CBZ55548.1 - 9.4 5.9 7.5 19 4.9 0.1 3.1 3 0 0 3 3 3 0 DDHD domain tRNA-synt_1 PF00133.17 CBZ55549.1 - 1e-57 195.4 0.7 3.8e-18 64.8 0.0 5.2 5 0 0 5 5 5 5 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.6 CBZ55549.1 - 5.9e-06 25.1 0.0 0.058 12.0 0.0 3.5 4 0 0 4 4 4 2 tRNA synthetases class I (M) Anticodon_1 PF08264.8 CBZ55549.1 - 0.00058 19.6 0.1 0.0011 18.7 0.0 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA Hid1 PF12722.2 CBZ55549.1 - 0.59 7.7 0.7 1.1 6.8 0.5 1.3 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein NMD3 PF04981.8 CBZ55551.1 - 1.5e-44 151.9 1.1 2e-44 151.4 0.8 1.2 1 0 0 1 1 1 1 NMD3 family ADH_N PF08240.7 CBZ55551.1 - 0.075 12.7 0.0 16 5.3 0.0 2.3 2 0 0 2 2 2 0 Alcohol dehydrogenase GroES-like domain DUF4006 PF13179.1 CBZ55553.1 - 0.033 13.7 0.3 0.081 12.4 0.2 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF4006) DUF4131 PF13567.1 CBZ55553.1 - 9.5 5.5 8.4 7.9 5.8 2.3 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) Proteasome PF00227.21 CBZ55554.1 - 3.7e-37 127.4 0.0 5.9e-37 126.8 0.0 1.3 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 CBZ55554.1 - 1.7e-13 49.5 0.1 3.6e-13 48.5 0.1 1.6 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature OTU PF02338.14 CBZ55555.1 - 7e-06 26.6 0.0 1.8e-05 25.3 0.0 1.7 1 1 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.4 CBZ55555.1 - 0.068 12.5 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Peptidase C65 Otubain Nop25 PF09805.4 CBZ55556.1 - 1.1e-14 54.6 13.4 1.4e-14 54.3 9.3 1.1 1 0 0 1 1 1 1 Nucleolar protein 12 (25kDa) ERK-JNK_inhib PF15002.1 CBZ55556.1 - 0.13 11.6 3.6 0.16 11.2 2.5 1.1 1 0 0 1 1 1 0 ERK and JNK pathways, inhibitor BBS2_C PF14782.1 CBZ55556.1 - 0.18 10.3 4.5 0.23 9.9 3.1 1.1 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, C-terminal ATP-synt_E PF05680.7 CBZ55556.1 - 0.25 11.3 6.1 0.36 10.8 4.2 1.3 1 0 0 1 1 1 0 ATP synthase E chain Mnd1 PF03962.10 CBZ55556.1 - 0.31 10.6 5.0 0.39 10.3 3.4 1.1 1 0 0 1 1 1 0 Mnd1 family CMS1 PF14617.1 CBZ55556.1 - 0.95 8.4 5.4 1.2 8.1 3.8 1.1 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit MAS20 PF02064.10 CBZ55556.1 - 1.4 8.8 5.8 1.9 8.4 4.0 1.2 1 0 0 1 1 1 0 MAS20 protein import receptor TPX2 PF06886.6 CBZ55556.1 - 4.4 7.4 20.1 5.8 7.0 13.4 1.6 1 1 0 1 1 1 0 Targeting protein for Xklp2 (TPX2) RabGAP-TBC PF00566.13 CBZ55557.1 - 1.9e-37 128.8 0.1 2.8e-37 128.2 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Rhodanese PF00581.15 CBZ55557.1 - 0.027 14.7 0.0 0.28 11.5 0.0 2.5 3 0 0 3 3 3 0 Rhodanese-like domain Rad51 PF08423.6 CBZ55559.1 - 1.8e-127 423.5 0.2 3.1e-127 422.7 0.1 1.3 1 0 0 1 1 1 1 Rad51 RecA PF00154.16 CBZ55559.1 - 4.9e-10 38.9 0.1 7e-10 38.4 0.1 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein HHH_5 PF14520.1 CBZ55559.1 - 9.3e-10 38.5 0.2 2.7e-09 37.0 0.1 1.8 2 0 0 2 2 2 1 Helix-hairpin-helix domain AAA_25 PF13481.1 CBZ55559.1 - 5.9e-09 35.6 0.0 3.5e-08 33.0 0.0 1.9 2 0 0 2 2 2 1 AAA domain KaiC PF06745.8 CBZ55559.1 - 2.4e-05 23.5 0.3 6.1e-05 22.2 0.0 1.8 2 0 0 2 2 2 1 KaiC AAA PF00004.24 CBZ55559.1 - 0.00041 20.5 0.0 0.0032 17.6 0.0 2.3 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) HHH PF00633.18 CBZ55559.1 - 0.0016 17.9 0.1 0.0038 16.8 0.1 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif SpoU_methylase PF00588.14 CBZ55560.1 - 8.2e-23 80.8 0.0 1.4e-22 80.0 0.0 1.4 1 0 0 1 1 1 1 SpoU rRNA Methylase family HAD PF12710.2 CBZ55561.1 - 6.1e-12 46.0 0.0 3.3e-11 43.7 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 CBZ55561.1 - 2.1e-10 41.3 0.0 9.4e-05 22.9 0.1 3.6 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 CBZ55561.1 - 2e-07 30.2 0.0 3.7e-06 26.1 0.0 2.4 1 1 0 1 1 1 1 E1-E2 ATPase Hydrolase_3 PF08282.7 CBZ55561.1 - 0.024 14.1 0.1 0.086 12.4 0.0 1.8 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase SPT16 PF08644.6 CBZ55562.1 - 0.15 11.8 0.3 0.41 10.4 0.2 1.7 1 0 0 1 1 1 0 FACT complex subunit (SPT16/CDC68) Chorein_N PF12624.2 CBZ55563.1 - 2.3e-21 75.4 0.1 4.4e-21 74.6 0.1 1.5 1 0 0 1 1 1 1 N-terminal region of Chorein, a TM vesicle-mediated sorter DUF1162 PF06650.7 CBZ55563.1 - 4.1e-11 42.5 0.0 6.8e-06 25.4 0.0 3.2 4 0 0 4 4 4 2 Protein of unknown function (DUF1162) PRTP PF01366.13 CBZ55563.1 - 0.42 8.5 2.6 0.63 7.9 0.4 2.1 2 0 0 2 2 2 0 Herpesvirus processing and transport protein DUF2014 PF09427.5 CBZ55563.1 - 2 7.5 0.0 3.6 6.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2014) FA_desaturase PF00487.19 CBZ55563.1 - 2.4 7.5 3.1 2 7.7 0.6 1.8 2 0 0 2 2 2 0 Fatty acid desaturase Big_3 PF07523.7 CBZ55564.1 - 0.067 13.2 0.0 0.27 11.3 0.0 1.9 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 3) DUF1510 PF07423.6 CBZ55565.1 - 0.13 11.6 0.4 0.32 10.3 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) DUF167 PF02594.11 CBZ55566.1 - 3.4e-13 49.3 0.0 6.6e-13 48.3 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised ACR, YggU family COG1872 Methyltransf_31 PF13847.1 CBZ55566.1 - 0.00017 21.1 0.0 0.00034 20.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CBZ55566.1 - 0.0011 19.5 0.0 0.0023 18.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 CBZ55566.1 - 0.002 17.2 0.0 0.0034 16.5 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.1 CBZ55566.1 - 0.0023 18.2 0.0 0.0048 17.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 CBZ55566.1 - 0.0088 16.0 0.0 0.015 15.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CBZ55566.1 - 0.012 15.3 0.0 0.019 14.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.7 CBZ55566.1 - 0.014 15.8 0.0 0.031 14.7 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain DUF2865 PF11064.3 CBZ55566.1 - 0.035 13.9 0.1 0.082 12.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2865) Methyltransf_11 PF08241.7 CBZ55566.1 - 0.045 14.2 0.0 0.088 13.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain DOT1 PF08123.8 CBZ55566.1 - 0.058 12.6 0.0 0.24 10.6 0.0 1.8 2 0 0 2 2 2 0 Histone methylation protein DOT1 NTP_transf_3 PF12804.2 CBZ55567.1 - 7.2e-11 42.4 0.0 1.5e-10 41.4 0.0 1.5 1 1 0 1 1 1 1 MobA-like NTP transferase domain NTP_transferase PF00483.18 CBZ55567.1 - 2.4e-08 33.5 0.0 4.1e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.19 CBZ55567.1 - 0.0096 15.3 0.1 2.1 7.9 0.0 2.8 1 1 1 2 2 2 2 Bacterial transferase hexapeptide (six repeats) CTP_transf_3 PF02348.14 CBZ55567.1 - 0.073 12.6 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 Cytidylyltransferase SMC_N PF02463.14 CBZ55568.1 - 6.2e-19 68.1 0.0 9.7e-19 67.4 0.0 1.3 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 CBZ55568.1 - 6.4e-15 56.0 0.0 6.4e-15 56.0 0.0 5.1 4 2 1 5 5 5 1 AAA domain AAA_29 PF13555.1 CBZ55568.1 - 0.00033 20.1 0.0 0.00065 19.1 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.1 CBZ55568.1 - 0.0057 16.6 0.1 0.017 15.1 0.0 1.8 2 0 0 2 2 2 1 AAA domain Reo_sigmaC PF04582.7 CBZ55568.1 - 0.0086 15.2 3.9 0.16 11.1 0.0 3.5 3 1 0 4 4 4 1 Reovirus sigma C capsid protein TBCC PF07986.7 CBZ55569.1 - 4.8e-10 38.8 0.1 7.4e-10 38.2 0.1 1.3 1 0 0 1 1 1 1 Tubulin binding cofactor C CAP_C PF08603.6 CBZ55569.1 - 0.00044 19.6 0.1 0.00066 19.0 0.0 1.2 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal AP2 PF00847.15 CBZ55570.1 - 3.8e-07 30.1 6.9 6.3e-07 29.4 4.8 1.4 1 0 0 1 1 1 1 AP2 domain DRIM PF07539.7 CBZ55571.1 - 2.4e-12 46.4 0.0 7e-12 44.9 0.0 1.8 1 0 0 1 1 1 1 Down-regulated in metastasis ANTH PF07651.11 CBZ55571.1 - 0.73 8.4 0.0 1.5 7.4 0.0 1.4 1 0 0 1 1 1 0 ANTH domain TB2_DP1_HVA22 PF03134.14 CBZ55573.1 - 0.0042 16.7 6.9 0.0064 16.2 4.8 1.3 1 0 0 1 1 1 1 TB2/DP1, HVA22 family DUF1218 PF06749.7 CBZ55573.1 - 5.1 7.6 6.5 18 5.8 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1218) Aminotran_5 PF00266.14 CBZ55574.1 - 3.1e-125 417.7 0.0 3.4e-106 355.1 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class-V Peptidase_M3 PF01432.15 CBZ55576.1 - 1.2e-26 93.7 0.0 3e-26 92.4 0.0 1.6 1 1 0 1 1 1 1 Peptidase family M3 Peptidase_M3_N PF08439.5 CBZ55576.1 - 0.14 12.2 0.2 0.54 10.3 0.0 2.1 2 0 0 2 2 2 0 Oligopeptidase F Reprolysin_2 PF13574.1 CBZ55576.1 - 0.17 11.9 0.1 0.35 10.9 0.1 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Ank_2 PF12796.2 CBZ55577.1 - 2.9e-40 136.4 4.5 8.2e-18 64.5 0.0 4.4 2 2 3 5 5 5 4 Ankyrin repeats (3 copies) Ank PF00023.25 CBZ55577.1 - 1.1e-37 125.9 10.9 2.1e-07 30.3 0.0 8.0 7 1 1 8 8 8 6 Ankyrin repeat Ank_3 PF13606.1 CBZ55577.1 - 3.2e-33 110.4 6.1 8.1e-06 25.5 0.0 8.2 8 0 0 8 8 8 7 Ankyrin repeat Ank_4 PF13637.1 CBZ55577.1 - 1.5e-30 105.0 7.6 4.2e-10 39.8 0.0 6.2 5 2 3 8 8 6 6 Ankyrin repeats (many copies) Ank_5 PF13857.1 CBZ55577.1 - 1.9e-29 101.0 14.3 1.3e-08 34.7 0.1 6.6 3 2 4 7 7 6 6 Ankyrin repeats (many copies) TPR_11 PF13414.1 CBZ55577.1 - 4.8e-12 45.3 0.3 1.5e-11 43.7 0.2 1.9 1 0 0 1 1 1 1 TPR repeat TPR_2 PF07719.12 CBZ55577.1 - 2.7e-06 26.8 0.1 0.054 13.4 0.0 3.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.23 CBZ55577.1 - 3.7e-05 23.1 0.0 0.5 10.0 0.0 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 CBZ55577.1 - 0.00017 21.4 1.1 0.00046 20.0 0.1 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 CBZ55577.1 - 0.01 15.5 4.4 0.22 11.4 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.1 CBZ55577.1 - 0.012 16.1 2.2 6.7 7.6 0.0 4.7 2 1 3 5 5 3 0 Tetratricopeptide repeat DUF2225 PF09986.4 CBZ55577.1 - 0.014 14.8 2.6 0.026 13.9 1.7 1.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) TPR_7 PF13176.1 CBZ55577.1 - 0.015 15.0 0.1 0.19 11.6 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.1 CBZ55577.1 - 0.039 14.1 0.0 2.4 8.5 0.0 3.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.1 CBZ55577.1 - 0.38 11.5 0.0 0.38 11.5 0.0 4.1 4 1 1 5 5 4 0 Tetratricopeptide repeat DUF465 PF04325.8 CBZ55577.1 - 1.6 8.5 6.7 1.6 8.5 2.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF465) UQ_con PF00179.21 CBZ55578.1 - 8.8e-51 171.0 0.0 1.1e-50 170.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 CBZ55578.1 - 0.00019 21.1 0.0 0.00028 20.6 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 CBZ55578.1 - 0.014 15.2 0.1 0.022 14.6 0.1 1.4 1 1 0 1 1 1 0 RWD domain SET PF00856.23 CBZ55580.1 - 3.9e-08 33.7 2.0 1.2e-07 32.1 0.0 2.9 3 2 0 3 3 3 1 SET domain Lar_restr_allev PF14354.1 CBZ55580.1 - 0.13 12.5 4.4 0.13 12.5 0.5 2.9 1 1 1 2 2 2 0 Restriction alleviation protein Lar CytochromB561_N PF09786.4 CBZ55581.1 - 0.0035 15.8 0.2 0.019 13.4 0.0 2.0 2 0 0 2 2 2 1 Cytochrome B561, N terminal Shisa PF13908.1 CBZ55581.1 - 0.53 10.4 2.5 1 9.5 0.1 2.6 3 0 0 3 3 3 0 Wnt and FGF inhibitory regulator UPF0118 PF01594.11 CBZ55581.1 - 0.88 8.4 23.4 0.099 11.6 1.0 3.6 4 0 0 4 4 4 0 Domain of unknown function DUF20 Ank_2 PF12796.2 CBZ55584.1 - 6.2e-37 125.8 11.0 1.9e-20 72.9 0.2 4.3 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.1 CBZ55584.1 - 4.5e-29 100.3 5.8 2e-06 28.1 0.1 5.9 4 2 2 6 6 6 5 Ankyrin repeats (many copies) Ank PF00023.25 CBZ55584.1 - 2.2e-27 93.4 13.6 1e-06 28.2 0.1 6.5 5 1 1 6 6 6 5 Ankyrin repeat Ank_3 PF13606.1 CBZ55584.1 - 3.1e-22 76.4 3.8 7.5e-05 22.6 0.0 6.6 6 0 0 6 6 6 4 Ankyrin repeat Ank_5 PF13857.1 CBZ55584.1 - 2.8e-21 75.0 9.7 5.6e-05 23.2 0.1 5.7 3 2 2 5 5 5 5 Ankyrin repeats (many copies) TPR_11 PF13414.1 CBZ55584.1 - 1.6e-14 53.3 4.0 4.5e-10 39.0 1.1 2.8 2 0 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 CBZ55584.1 - 4.3e-12 44.9 4.9 0.0014 18.3 0.1 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.23 CBZ55584.1 - 4.8e-11 41.7 4.1 0.0013 18.2 0.0 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.1 CBZ55584.1 - 1.7e-07 31.0 6.1 5.2e-05 23.1 0.7 2.7 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.1 CBZ55584.1 - 1.1e-05 25.1 0.2 0.024 14.8 0.0 3.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 CBZ55584.1 - 4.6e-05 22.8 0.3 0.054 13.2 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 CBZ55584.1 - 6.8e-05 23.4 15.1 0.00022 21.7 2.6 3.8 4 0 0 4 4 2 2 Tetratricopeptide repeat TPR_19 PF14559.1 CBZ55584.1 - 0.00022 21.5 6.8 0.0044 17.3 0.8 3.8 3 1 1 4 4 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 CBZ55584.1 - 0.0011 19.4 20.1 0.0013 19.1 0.7 5.0 5 1 1 6 6 3 1 Tetratricopeptide repeat TPR_9 PF13371.1 CBZ55584.1 - 0.0027 17.5 3.7 0.0056 16.5 0.6 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.1 CBZ55584.1 - 0.0056 16.3 6.4 0.32 10.8 0.1 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat Apc3 PF12895.2 CBZ55584.1 - 0.0081 16.2 1.5 0.67 10.1 0.0 2.7 1 1 2 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_20 PF14561.1 CBZ55584.1 - 0.047 13.7 12.2 0.88 9.7 0.1 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat NYD-SP12_N PF15015.1 CBZ55584.1 - 0.096 10.8 0.2 0.19 9.9 0.2 1.4 1 1 0 1 1 1 0 Spermatogenesis-associated, N-terminal TPR_6 PF13174.1 CBZ55584.1 - 0.58 10.7 3.0 6.1 7.5 0.7 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.1 CBZ55584.1 - 1.7 8.6 7.1 8.5 6.4 0.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat Ribosomal_S15 PF00312.17 CBZ55585.1 - 2.2e-15 56.1 1.1 3.8e-15 55.4 0.8 1.4 1 0 0 1 1 1 1 Ribosomal protein S15 VHS PF00790.14 CBZ55586.1 - 0.0031 17.1 0.8 0.17 11.4 0.0 2.2 1 1 1 2 2 2 2 VHS domain Peptidase_C78 PF07910.8 CBZ55587.1 - 3.9e-41 140.5 0.0 1.5e-35 122.3 0.0 2.2 2 0 0 2 2 2 2 Peptidase family C78 KOW PF00467.24 CBZ55588.1 - 0.00066 19.2 0.9 0.00066 19.2 0.6 2.1 2 0 0 2 2 2 1 KOW motif IMCp PF12314.3 CBZ55589.1 - 1.7e-07 31.2 59.4 0.0023 18.0 27.0 3.6 1 1 2 3 3 3 3 Inner membrane complex protein Helicase_C_2 PF13307.1 CBZ55590.1 - 1.2e-31 109.9 0.0 4.7e-14 52.6 0.0 3.3 3 0 0 3 3 3 2 Helicase C-terminal domain DEAD_2 PF06733.10 CBZ55590.1 - 1.1e-21 77.0 0.1 7.6e-17 61.2 0.0 3.0 2 1 1 3 3 3 2 DEAD_2 DEAD PF00270.24 CBZ55590.1 - 0.0041 16.6 0.0 1.6 8.1 0.0 2.5 2 0 0 2 2 2 2 DEAD/DEAH box helicase ResIII PF04851.10 CBZ55590.1 - 0.0043 16.9 0.1 2.1 8.1 0.0 2.5 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit SNF2_N PF00176.18 CBZ55590.1 - 0.17 10.6 0.3 0.91 8.2 0.2 2.0 1 1 0 1 1 1 0 SNF2 family N-terminal domain GFO_IDH_MocA_C PF02894.12 CBZ55591.1 - 0.076 12.8 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 Oxidoreductase family, C-terminal alpha/beta domain HTH_Tnp_Tc5 PF03221.11 CBZ55593.1 - 2.3e-07 30.5 0.0 4.9e-07 29.4 0.0 1.6 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_Tnp_1 PF01527.15 CBZ55593.1 - 1.5e-05 24.8 0.1 4.6e-05 23.3 0.1 1.8 1 0 0 1 1 1 1 Transposase BrkDBD PF09607.5 CBZ55593.1 - 0.00019 20.9 0.0 0.00035 20.0 0.0 1.4 1 0 0 1 1 1 1 Brinker DNA-binding domain HTH_29 PF13551.1 CBZ55593.1 - 0.0026 17.8 0.9 0.0074 16.4 0.6 1.9 1 0 0 1 1 1 1 Winged helix-turn helix HTH_28 PF13518.1 CBZ55593.1 - 0.0094 15.9 0.0 0.027 14.4 0.0 1.8 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.1 CBZ55593.1 - 0.11 12.2 0.0 0.26 10.9 0.0 1.6 1 0 0 1 1 1 0 Homeodomain-like domain Acatn PF13000.2 CBZ55594.1 - 6.8e-68 229.5 14.1 5.1e-37 127.6 4.6 4.0 2 2 0 2 2 2 2 Acetyl-coenzyme A transporter 1 Med21 PF11221.3 CBZ55595.1 - 2.2e-06 27.7 4.0 4.1e-06 26.8 2.8 1.5 1 0 0 1 1 1 1 Subunit 21 of Mediator complex DivIC PF04977.10 CBZ55595.1 - 0.036 13.5 0.9 0.07 12.6 0.6 1.5 1 0 0 1 1 1 0 Septum formation initiator Daxx PF03344.10 CBZ55595.1 - 4 5.8 18.6 6.2 5.1 12.9 1.2 1 1 0 1 1 1 0 Daxx Family Ubiq_cyt_C_chap PF03981.7 CBZ55596.1 - 3e-14 53.0 0.5 4.1e-14 52.6 0.3 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome C chaperone DUF2762 PF10960.3 CBZ55598.1 - 0.83 9.4 7.1 4.7 6.9 0.3 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2762) AP2 PF00847.15 CBZ55599.1 - 3.5e-07 30.2 2.9 0.016 15.3 0.5 3.5 3 0 0 3 3 3 3 AP2 domain DUF4278 PF14105.1 CBZ55600.1 - 0.0029 17.5 0.0 0.0045 16.9 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4278) PWWP PF00855.12 CBZ55601.1 - 0.082 13.1 0.4 0.32 11.2 0.3 2.0 1 0 0 1 1 1 0 PWWP domain DUF605 PF04652.11 CBZ55602.1 - 0.98 8.7 14.8 1.2 8.4 10.3 1.1 1 0 0 1 1 1 0 Vta1 like DUF605 PF04652.11 CBZ55603.1 - 0.83 8.9 13.3 0.97 8.7 9.2 1.1 1 0 0 1 1 1 0 Vta1 like YtxH PF12732.2 CBZ55604.1 - 0.0044 17.3 0.3 0.009 16.3 0.2 1.5 1 0 0 1 1 1 1 YtxH-like protein Herpes_gE PF02480.11 CBZ55604.1 - 0.15 10.3 0.1 0.17 10.0 0.1 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E ERO1 PF04137.10 CBZ55605.1 - 2.6e-61 207.6 0.0 3.4e-61 207.2 0.0 1.1 1 0 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) SURF4 PF02077.10 CBZ55605.1 - 0.031 13.6 0.2 0.052 12.9 0.1 1.3 1 0 0 1 1 1 0 SURF4 family DUF342 PF03961.8 CBZ55606.1 - 0.044 12.1 7.6 0.054 11.9 5.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) UPF0449 PF15136.1 CBZ55606.1 - 0.13 12.4 6.2 0.72 10.1 4.3 2.2 1 1 0 1 1 1 0 Uncharacterised protein family UPF0449 IncA PF04156.9 CBZ55606.1 - 0.42 10.1 5.8 0.49 9.9 4.0 1.3 1 0 0 1 1 1 0 IncA protein MCLC PF05934.6 CBZ55606.1 - 0.83 7.8 3.0 1.2 7.3 2.1 1.1 1 0 0 1 1 1 0 Mid-1-related chloride channel (MCLC) DUF3373 PF11853.3 CBZ55606.1 - 0.94 7.9 3.8 1 7.7 2.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) Atg14 PF10186.4 CBZ55606.1 - 2.3 7.0 13.4 3.3 6.5 9.2 1.3 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Mito_carr PF00153.22 CBZ55607.1 - 2.2e-71 235.6 1.6 2.8e-26 91.0 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF4257 PF14074.1 CBZ55607.1 - 0.032 13.8 0.1 4.1 7.1 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4257) Aminotran_5 PF00266.14 CBZ55608.1 - 1.4e-24 86.5 0.0 3.2e-23 82.0 0.0 2.3 2 1 0 2 2 2 2 Aminotransferase class-V CAF1 PF04857.15 CBZ55609.1 - 3.2e-35 121.7 0.0 6.5e-35 120.7 0.0 1.5 1 1 0 1 1 1 1 CAF1 family ribonuclease RrnaAD PF00398.15 CBZ55611.1 - 5.4e-06 25.6 0.0 8.5e-06 24.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase DUF605 PF04652.11 CBZ55611.1 - 4.7e-05 22.9 25.3 4.7e-05 22.9 17.5 1.7 2 0 0 2 2 2 1 Vta1 like RrnaAD PF00398.15 CBZ55612.1 - 1.1e-15 57.3 0.0 1.4e-15 57.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase AAA PF00004.24 CBZ55613.1 - 2.5e-41 140.9 0.0 6.5e-41 139.6 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 CBZ55613.1 - 1.2e-06 28.3 0.1 7.2e-06 25.7 0.1 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 CBZ55613.1 - 7.2e-06 25.2 0.0 8.2e-05 21.7 0.0 2.0 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 CBZ55613.1 - 2.2e-05 24.5 0.2 0.0021 18.0 0.0 2.7 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 CBZ55613.1 - 0.00025 21.2 0.5 0.018 15.1 0.0 2.5 1 1 1 2 2 2 1 AAA domain AAA_2 PF07724.9 CBZ55613.1 - 0.00035 20.5 0.0 0.0014 18.6 0.0 1.9 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.1 CBZ55613.1 - 0.0025 17.7 0.2 0.0067 16.3 0.0 1.8 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.16 CBZ55613.1 - 0.0037 16.4 0.0 0.011 14.9 0.0 1.8 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_19 PF13245.1 CBZ55613.1 - 0.0046 16.6 0.3 0.013 15.2 0.2 1.7 1 0 0 1 1 1 1 Part of AAA domain IstB_IS21 PF01695.12 CBZ55613.1 - 0.005 16.2 0.0 0.0091 15.4 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein PhoH PF02562.11 CBZ55613.1 - 0.0069 15.6 0.0 0.013 14.7 0.0 1.4 1 0 0 1 1 1 1 PhoH-like protein DUF815 PF05673.8 CBZ55613.1 - 0.0071 15.3 0.0 0.011 14.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_17 PF13207.1 CBZ55613.1 - 0.0092 16.7 0.1 0.038 14.8 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.1 CBZ55613.1 - 0.019 14.4 0.5 0.13 11.6 0.1 2.3 1 1 1 2 2 2 0 AAA domain AAA_24 PF13479.1 CBZ55613.1 - 0.029 13.9 0.1 0.06 12.9 0.1 1.5 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 CBZ55613.1 - 0.03 13.4 0.1 0.069 12.2 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin TIP49 PF06068.8 CBZ55613.1 - 0.045 12.4 0.0 0.12 11.0 0.0 1.7 2 0 0 2 2 2 0 TIP49 C-terminus AAA_14 PF13173.1 CBZ55613.1 - 0.046 13.6 0.0 0.09 12.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 CBZ55613.1 - 0.081 12.4 0.1 0.3 10.5 0.0 2.0 2 1 0 2 2 2 0 Sigma-54 interaction domain KaiC PF06745.8 CBZ55613.1 - 0.085 11.9 0.0 0.21 10.6 0.0 1.7 1 0 0 1 1 1 0 KaiC NACHT PF05729.7 CBZ55613.1 - 0.14 11.8 0.4 2.4 7.7 0.0 2.3 1 1 0 2 2 2 0 NACHT domain RNA_helicase PF00910.17 CBZ55613.1 - 0.17 12.0 0.0 0.36 11.0 0.0 1.6 1 0 0 1 1 1 0 RNA helicase SNARE PF05739.14 CBZ55614.1 - 1.8e-09 37.1 2.0 1.8e-09 37.1 1.4 2.1 3 0 0 3 3 3 1 SNARE domain DUF4559 PF15112.1 CBZ55614.1 - 0.011 14.8 0.4 0.024 13.8 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) TSC22 PF01166.13 CBZ55614.1 - 0.018 15.0 0.4 2.1 8.3 0.1 3.0 2 0 0 2 2 2 0 TSC-22/dip/bun family Syntaxin-6_N PF09177.6 CBZ55614.1 - 0.026 14.9 4.2 0.035 14.5 0.5 2.3 2 1 0 2 2 2 0 Syntaxin 6, N-terminal Fusion_gly PF00523.13 CBZ55614.1 - 0.086 10.8 0.2 0.11 10.5 0.2 1.1 1 0 0 1 1 1 0 Fusion glycoprotein F0 Exonuc_V_gamma PF04257.9 CBZ55614.1 - 0.14 10.1 3.7 2.6 5.9 0.1 2.1 1 1 1 2 2 2 0 Exodeoxyribonuclease V, gamma subunit FliJ PF02050.11 CBZ55614.1 - 0.19 11.8 7.2 2.2 8.3 0.2 3.1 2 1 1 3 3 3 0 Flagellar FliJ protein LSM PF01423.17 CBZ55615.1 - 2.4e-17 62.2 0.2 5.2e-17 61.1 0.2 1.5 1 1 0 1 1 1 1 LSM domain Flag1_repress PF03614.8 CBZ55615.1 - 0.023 14.2 0.0 0.03 13.9 0.0 1.1 1 0 0 1 1 1 0 Repressor of phase-1 flagellin tRNA-synt_2b PF00587.20 CBZ55617.1 - 1.6e-40 138.4 0.0 2.8e-40 137.7 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 CBZ55617.1 - 1.5e-19 69.7 0.1 3.6e-19 68.5 0.1 1.7 1 0 0 1 1 1 1 Anticodon binding domain tRNA_SAD PF07973.9 CBZ55617.1 - 3.1e-11 42.9 0.0 6e-11 42.0 0.0 1.5 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain TGS PF02824.16 CBZ55617.1 - 0.00089 19.0 0.0 0.0043 16.8 0.0 2.2 1 1 0 1 1 1 1 TGS domain DUF2188 PF09954.4 CBZ55617.1 - 0.011 15.5 0.6 0.032 14.1 0.4 1.8 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2188) MtN3_slv PF03083.11 CBZ55618.1 - 5.7e-40 135.0 6.9 8.3e-21 73.6 0.3 2.4 2 0 0 2 2 2 2 Sugar efflux transporter for intercellular exchange TPR_11 PF13414.1 CBZ55619.1 - 6.2e-21 73.8 11.1 3.9e-10 39.2 0.1 4.3 2 1 1 4 4 4 4 TPR repeat TPR_1 PF00515.23 CBZ55619.1 - 9.8e-20 69.2 2.2 2.6e-05 23.6 0.0 5.4 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.12 CBZ55619.1 - 1.4e-17 62.1 9.4 4e-05 23.2 0.1 5.5 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.1 CBZ55619.1 - 4.4e-13 49.5 13.4 3.1e-07 30.8 1.0 4.3 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.1 CBZ55619.1 - 8.2e-13 48.0 7.9 4.1e-07 29.8 0.2 4.3 2 1 3 5 5 5 4 Tetratricopeptide repeat TPR_8 PF13181.1 CBZ55619.1 - 5.6e-12 44.5 0.1 0.00098 18.7 0.1 4.9 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_6 PF13174.1 CBZ55619.1 - 1.1e-09 38.1 4.5 0.065 13.7 0.1 4.9 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_17 PF13431.1 CBZ55619.1 - 1.2e-09 37.5 0.5 0.039 14.1 0.0 4.9 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.1 CBZ55619.1 - 3e-09 36.6 14.7 0.0045 17.5 0.3 4.7 3 2 2 5 5 4 3 Tetratricopeptide repeat TPR_9 PF13371.1 CBZ55619.1 - 5.1e-08 32.6 12.5 5e-07 29.4 0.4 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 CBZ55619.1 - 1.4e-07 31.7 11.0 0.0015 18.8 0.6 3.6 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 CBZ55619.1 - 2.7e-05 23.6 6.9 0.017 14.8 0.0 4.8 5 0 0 5 5 5 2 Tetratricopeptide repeat Apc3 PF12895.2 CBZ55619.1 - 3.8e-05 23.7 4.1 0.00045 20.2 0.4 2.9 1 1 1 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.1 CBZ55619.1 - 4.5e-05 22.6 1.9 4.5e-05 22.6 1.3 3.1 2 1 0 2 2 2 1 Tetratricopeptide repeat RPN7 PF10602.4 CBZ55619.1 - 0.0011 18.3 0.1 0.0033 16.8 0.0 1.8 1 0 0 1 1 1 1 26S proteasome subunit RPN7 DUF2225 PF09986.4 CBZ55619.1 - 0.047 13.1 0.3 1.4 8.3 0.1 2.4 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) EST1_DNA_bind PF10373.4 CBZ55619.1 - 0.099 11.8 0.1 0.13 11.4 0.0 1.2 1 0 0 1 1 1 0 Est1 DNA/RNA binding domain Nanovirus_C8 PF05629.6 CBZ55619.1 - 0.11 12.2 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 Nanovirus component 8 (C8) protein TPR_10 PF13374.1 CBZ55619.1 - 1.6 8.7 12.8 2.8 8.0 0.2 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 CBZ55619.1 - 2.6 7.9 5.3 9.7 6.1 0.3 3.4 4 0 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat tRNA-synt_1e PF01406.14 CBZ55622.1 - 7.9e-117 389.6 0.0 1.3e-116 388.9 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.6 CBZ55622.1 - 7.5e-10 38.0 0.0 0.00028 19.6 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 CBZ55622.1 - 0.00052 18.1 0.0 0.0015 16.6 0.0 1.6 2 0 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) Peptidase_C70 PF12385.3 CBZ55622.1 - 0.059 13.0 0.1 3.4 7.3 0.0 2.5 2 0 0 2 2 2 0 Papain-like cysteine protease AvrRpt2 DALR_2 PF09190.6 CBZ55622.1 - 0.082 13.1 0.1 0.22 11.7 0.0 1.8 1 0 0 1 1 1 0 DALR domain TTL PF03133.10 CBZ55627.1 - 4.1e-52 176.9 0.0 8.1e-52 175.9 0.0 1.4 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.1 CBZ55627.1 - 2e-05 23.5 0.2 0.0099 14.7 0.0 3.0 2 1 1 3 3 3 2 YheC/D like ATP-grasp ATP-synt_ab_C PF00306.22 CBZ55627.1 - 0.24 11.8 0.0 0.48 10.9 0.0 1.4 1 0 0 1 1 1 0 ATP synthase alpha/beta chain, C terminal domain Fumble PF03630.9 CBZ55628.1 - 2.5e-71 240.3 0.0 2.9e-64 217.0 0.0 3.1 3 0 0 3 3 3 3 Fumble Peptidase_C2 PF00648.16 CBZ55629.1 - 0.0017 17.4 0.0 0.0033 16.4 0.0 1.4 1 0 0 1 1 1 1 Calpain family cysteine protease Spc7 PF08317.6 CBZ55629.1 - 1 7.9 8.1 1.6 7.3 5.6 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF1220 PF06758.8 CBZ55629.1 - 3.9 7.3 7.6 11 5.8 0.3 2.8 2 0 0 2 2 2 0 Repeat of unknown function (DUF1220) GDA1_CD39 PF01150.12 CBZ55630.1 - 3.7e-64 216.8 0.0 9.1e-45 152.9 0.0 2.2 2 0 0 2 2 2 2 GDA1/CD39 (nucleoside phosphatase) family DUF1722 PF08349.6 CBZ55630.1 - 0.19 11.6 0.0 0.36 10.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1722) Rrf2 PF02082.15 CBZ55632.1 - 0.096 12.8 0.8 0.46 10.6 0.1 2.4 1 1 1 2 2 2 0 Transcriptional regulator Mto2_bdg PF12808.2 CBZ55632.1 - 0.14 12.2 1.0 1 9.5 0.0 2.6 2 0 0 2 2 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region DUF912 PF06024.7 CBZ55632.1 - 0.17 11.9 1.0 0.36 10.9 0.1 1.9 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Sulfatase_C PF14707.1 CBZ55633.1 - 0.079 13.2 0.3 0.13 12.5 0.2 1.3 1 0 0 1 1 1 0 C-terminal region of aryl-sulfatase SF-assemblin PF06705.6 CBZ55634.1 - 2.6e-45 154.4 24.8 3.2e-45 154.2 17.2 1.0 1 0 0 1 1 1 1 SF-assemblin/beta giardin FliS PF02561.9 CBZ55634.1 - 0.041 13.7 1.3 0.057 13.2 0.1 1.8 2 0 0 2 2 2 0 Flagellar protein FliS MBF1 PF08523.5 CBZ55634.1 - 0.049 13.6 0.4 0.16 11.9 0.3 2.0 2 0 0 2 2 2 0 Multiprotein bridging factor 1 EABR PF12180.3 CBZ55634.1 - 0.073 12.4 0.4 0.073 12.4 0.3 1.9 2 0 0 2 2 2 0 TSG101 and ALIX binding domain of CEP55 TFR_dimer PF04253.10 CBZ55634.1 - 0.27 10.8 1.8 0.52 9.9 0.2 2.4 2 1 0 2 2 2 0 Transferrin receptor-like dimerisation domain SPX PF03105.14 CBZ55634.1 - 2.5 7.8 11.7 3 7.5 7.7 1.4 1 1 0 1 1 1 0 SPX domain 6PGD PF00393.14 CBZ55635.1 - 5.4e-101 337.6 0.0 1e-100 336.7 0.0 1.4 1 1 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 CBZ55635.1 - 4.2e-42 143.7 0.0 6.6e-42 143.1 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.13 CBZ55635.1 - 0.011 15.3 0.0 0.021 14.4 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF2625 PF10946.3 CBZ55635.1 - 0.11 11.4 0.0 0.19 10.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF2625 zf-C3HC4_3 PF13920.1 CBZ55636.1 - 0.00033 20.2 16.1 0.0006 19.4 9.3 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Ank_2 PF12796.2 CBZ55636.1 - 0.016 15.5 0.0 0.061 13.6 0.0 2.0 1 1 0 1 1 1 0 Ankyrin repeats (3 copies) Ank_3 PF13606.1 CBZ55636.1 - 0.066 13.4 0.0 0.77 10.1 0.0 2.7 2 0 0 2 2 2 0 Ankyrin repeat Ank_4 PF13637.1 CBZ55636.1 - 0.17 12.4 0.0 1.4 9.5 0.0 2.5 2 0 0 2 2 2 0 Ankyrin repeats (many copies) zf-C3HC4_2 PF13923.1 CBZ55636.1 - 5.9 7.0 15.3 1 9.4 7.3 2.4 2 1 1 3 3 3 0 Zinc finger, C3HC4 type (RING finger) GTP_EFTU PF00009.22 CBZ55637.1 - 2.4e-46 157.5 0.0 4.3e-46 156.7 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain LepA_C PF06421.7 CBZ55637.1 - 5.2e-38 129.2 0.8 1.2e-37 128.0 0.6 1.7 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus EFG_C PF00679.19 CBZ55637.1 - 4.3e-11 42.5 0.0 8.9e-11 41.5 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.1 CBZ55637.1 - 0.0011 18.8 0.0 0.0064 16.3 0.0 2.3 1 1 1 2 2 2 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.20 CBZ55637.1 - 0.007 16.4 0.3 0.017 15.2 0.0 1.8 2 0 0 2 2 2 1 Elongation factor Tu domain 2 Arrestin_N PF00339.24 CBZ55638.1 - 4.4e-14 52.5 0.2 3.4e-13 49.6 0.0 2.3 3 0 0 3 3 3 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.17 CBZ55638.1 - 3.5e-11 43.3 0.0 6.1e-09 36.1 0.0 2.3 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain DUF4119 PF13494.1 CBZ55638.1 - 0.11 12.4 0.0 0.21 11.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function, B. Theta Gene description (DUF4119) Gpi16 PF04113.9 CBZ55639.1 - 1.4e-46 158.7 0.0 1e-28 99.7 0.0 3.3 2 2 0 2 2 2 2 Gpi16 subunit, GPI transamidase component RNA_pol_Rpb1_5 PF04998.12 CBZ55640.1 - 0.073 12.3 1.1 0.12 11.6 0.8 1.2 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 SAG PF04092.8 CBZ55641.1 - 1.7e-39 135.0 4.0 1.6e-22 80.1 0.9 2.1 2 0 0 2 2 2 2 SRS domain zf-ZPR1 PF03367.8 CBZ55643.1 - 7.4e-86 285.2 0.0 3e-48 163.0 0.0 2.5 2 0 0 2 2 2 2 ZPR1 zinc-finger domain Zn_Tnp_IS1595 PF12760.2 CBZ55643.1 - 0.051 13.3 7.3 3.5 7.5 0.2 4.2 4 0 0 4 4 4 0 Transposase zinc-ribbon domain Zn-ribbon_8 PF09723.5 CBZ55643.1 - 0.14 12.0 4.7 25 4.9 0.0 4.2 4 0 0 4 4 4 0 Zinc ribbon domain zf-RING_3 PF14369.1 CBZ55643.1 - 1.7 8.7 8.6 20 5.2 0.1 3.8 4 0 0 4 4 4 0 zinc-finger zinc_ribbon_2 PF13240.1 CBZ55643.1 - 3.3 7.3 17.1 1.7 8.2 0.2 4.4 4 0 0 4 4 4 0 zinc-ribbon domain zf-Di19 PF05605.7 CBZ55643.1 - 4.1 7.5 6.4 16 5.6 0.1 3.2 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding zf-ISL3 PF14690.1 CBZ55643.1 - 5.6 7.0 9.0 12 5.9 0.3 4.0 4 0 0 4 4 4 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 Thioredoxin PF00085.15 CBZ55644.1 - 2.8e-06 26.9 0.0 4.5e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin RHH_2 PF03693.9 CBZ55644.1 - 0.056 13.6 3.3 0.1 12.8 2.3 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0156) DUF4224 PF13986.1 CBZ55644.1 - 0.074 12.6 1.0 0.17 11.4 0.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4224) SAG PF04092.8 CBZ55645.1 - 1.4e-37 128.8 0.8 4.5e-22 78.7 0.1 2.1 2 0 0 2 2 2 2 SRS domain DUF3757 PF12582.3 CBZ55645.1 - 0.028 14.5 0.0 0.062 13.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3757) FCH PF00611.18 CBZ55646.1 - 0.0024 17.9 0.3 0.0099 16.0 0.0 2.1 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain DUF1864 PF08933.6 CBZ55646.1 - 0.19 10.2 0.4 1.5 7.2 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1864) DUF2217 PF10265.4 CBZ55646.1 - 2.4 6.8 6.8 5.5 5.6 4.7 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) DUF1604 PF07713.8 CBZ55647.1 - 4.6e-09 35.9 0.3 4.6e-09 35.9 0.2 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1604) Kinase-like PF14531.1 CBZ55648.1 - 1e-108 362.6 0.0 1.3e-108 362.3 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Pkinase PF00069.20 CBZ55648.1 - 0.00012 21.2 0.0 0.0014 17.7 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain MCM PF00493.18 CBZ55651.1 - 1.3e-132 441.5 0.0 1.9e-132 441.1 0.0 1.2 1 0 0 1 1 1 1 MCM2/3/5 family Mg_chelatase PF01078.16 CBZ55651.1 - 1.2e-05 24.6 0.0 3.9e-05 22.8 0.0 1.9 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 CBZ55651.1 - 0.0099 15.4 0.0 0.037 13.6 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 CBZ55651.1 - 0.019 14.7 0.0 0.055 13.1 0.0 1.9 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) ProRS-C_1 PF09180.6 CBZ55652.1 - 1.1e-26 92.4 0.1 2.9e-26 91.1 0.1 1.8 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal HGTP_anticodon PF03129.15 CBZ55652.1 - 1e-19 70.2 0.0 3.2e-19 68.6 0.0 1.9 1 0 0 1 1 1 1 Anticodon binding domain tRNA_edit PF04073.10 CBZ55652.1 - 1.7e-18 66.6 0.4 2.9e-18 65.8 0.3 1.4 1 0 0 1 1 1 1 Aminoacyl-tRNA editing domain tRNA-synt_2b PF00587.20 CBZ55652.1 - 1.2e-16 60.7 0.1 2.9e-16 59.5 0.0 1.6 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) TMP-TENI PF02581.12 CBZ55652.1 - 0.11 11.5 0.1 0.87 8.6 0.0 2.2 2 0 0 2 2 2 0 Thiamine monophosphate synthase/TENI Ribosomal_S10 PF00338.17 CBZ55653.1 - 6e-08 32.4 0.1 1.4e-07 31.2 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e DUF4375 PF14300.1 CBZ55653.1 - 2.4 8.1 5.8 25 4.8 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4375) CKS PF01111.14 CBZ55654.1 - 2.8e-17 62.2 0.1 5.7e-17 61.3 0.1 1.5 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit HMG_box PF00505.14 CBZ55655.1 - 1.2e-19 70.3 3.2 2e-19 69.5 2.2 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 CBZ55655.1 - 6e-16 58.5 2.7 9.7e-16 57.9 1.9 1.3 1 0 0 1 1 1 1 HMG-box domain HMG_box_5 PF14887.1 CBZ55655.1 - 0.0045 16.7 2.6 0.0045 16.7 1.8 1.7 1 1 1 2 2 2 1 HMG (high mobility group) box 5 KRAB PF01352.22 CBZ55655.1 - 0.054 12.9 0.1 0.087 12.2 0.0 1.3 1 0 0 1 1 1 0 KRAB box ubiquitin PF00240.18 CBZ55656.1 - 2.6e-241 779.5 38.0 6.8e-34 115.0 0.3 7.0 7 0 0 7 7 7 7 Ubiquitin family Rad60-SLD PF11976.3 CBZ55656.1 - 1.3e-138 450.8 37.9 3.8e-19 68.1 0.3 7.0 7 0 0 7 7 7 7 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 CBZ55656.1 - 2.2e-45 152.8 16.2 0.00012 22.2 0.0 9.1 7 7 0 7 7 7 7 Ubiquitin-like domain Telomere_Sde2 PF13019.1 CBZ55656.1 - 2.6e-34 118.2 0.5 0.0079 15.8 0.0 7.0 7 0 0 7 7 7 7 Telomere stability and silencing Rad60-SLD_2 PF13881.1 CBZ55656.1 - 1.4e-22 79.6 9.7 0.26 11.1 0.0 8.0 7 0 0 7 7 7 7 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 CBZ55656.1 - 1.9e-22 79.2 3.8 0.48 10.6 0.0 7.2 1 1 2 7 7 7 7 DUF2407 ubiquitin-like domain DUF2870 PF11069.3 CBZ55656.1 - 3.2e-18 65.5 0.0 3.1 7.9 0.0 7.7 7 0 0 7 7 7 7 Protein of unknown function (DUF2870) TUG-UBL1 PF11470.3 CBZ55656.1 - 7.1e-16 57.8 11.2 1.7 8.5 0.0 7.2 7 0 0 7 7 7 7 GLUT4 regulating protein TUG USP7_C2 PF14533.1 CBZ55656.1 - 5.2e-09 35.8 9.8 12 5.2 0.0 6.9 1 1 3 7 7 7 0 Ubiquitin-specific protease C-terminal FlgD_ig PF13860.1 CBZ55656.1 - 4.5e-08 32.7 12.0 23 4.8 0.0 7.2 7 0 0 7 7 7 0 FlgD Ig-like domain EMG1 PF03587.9 CBZ55656.1 - 1.5e-06 27.6 4.1 36 3.5 0.0 6.6 7 0 0 7 7 7 0 EMG1/NEP1 methyltransferase CTDII PF01556.13 CBZ55656.1 - 0.0003 20.6 30.2 10 6.1 0.2 7.2 1 1 5 7 7 7 6 DnaJ C terminal domain FERM_N PF09379.5 CBZ55656.1 - 0.0047 16.9 18.7 90 3.2 0.1 9.1 7 7 0 7 7 7 0 FERM N-terminal domain GABP-alpha PF11620.3 CBZ55656.1 - 0.011 15.7 14.3 1.1e+02 2.8 0.0 6.7 7 0 0 7 7 7 0 GA-binding protein alpha chain ATP-synt_ab PF00006.20 CBZ55658.1 - 1.8e-59 200.8 0.0 2.4e-59 200.4 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 CBZ55658.1 - 1.3e-17 64.2 0.3 2.9e-17 63.1 0.2 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 CBZ55658.1 - 1.6e-10 41.0 0.8 3.1e-10 40.1 0.5 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.5 CBZ55658.1 - 0.094 12.6 0.2 0.2 11.5 0.1 1.5 1 0 0 1 1 1 0 HAS barrel domain PRP3 PF08572.5 CBZ55659.1 - 6.8e-46 156.4 21.0 6.8e-46 156.4 14.5 3.0 3 1 0 3 3 3 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.7 CBZ55659.1 - 2e-22 79.2 1.0 5.5e-22 77.8 0.1 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF1115) Ribosom_S12_S23 PF00164.20 CBZ55660.1 - 1.5e-37 127.7 1.1 2.4e-37 127.0 0.7 1.2 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Acetyltransf_1 PF00583.19 CBZ55661.1 - 4.9e-12 45.7 0.1 7.5e-12 45.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 CBZ55661.1 - 0.00038 20.1 0.0 0.00058 19.5 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.1 CBZ55661.1 - 0.00081 19.5 0.0 0.0012 18.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 CBZ55661.1 - 0.003 17.6 0.0 0.0047 17.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 CBZ55661.1 - 0.12 12.2 0.1 0.24 11.2 0.1 1.5 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Cytochrom_C PF00034.16 CBZ55662.1 - 2.7e-11 44.1 0.1 4.6e-11 43.4 0.1 1.4 1 1 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.1 CBZ55662.1 - 6.2e-07 29.4 2.9 2.2e-06 27.7 2.0 1.8 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.1 CBZ55662.1 - 0.00023 20.6 0.0 0.00096 18.6 0.0 1.8 2 0 0 2 2 2 1 Cytochrome c-550 domain Cytochrom_C1 PF02167.10 CBZ55662.1 - 0.021 14.5 0.0 0.03 13.9 0.0 1.3 1 0 0 1 1 1 0 Cytochrome C1 family Cytochrome-c551 PF10643.4 CBZ55662.1 - 0.064 12.5 0.1 0.09 12.0 0.0 1.2 1 0 0 1 1 1 0 Photosystem P840 reaction-centre cytochrome c-551 Macoilin PF09726.4 CBZ55663.1 - 4.1 5.5 11.7 6 5.0 8.1 1.1 1 0 0 1 1 1 0 Transmembrane protein Ipi1_N PF12333.3 CBZ55664.1 - 0.051 13.5 0.3 0.73 9.8 0.0 3.1 3 0 0 3 3 3 0 Rix1 complex component involved in 60S ribosome maturation Ras PF00071.17 CBZ55665.1 - 5.2e-54 182.0 0.1 6.2e-54 181.7 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CBZ55665.1 - 2.1e-20 73.3 0.0 3.2e-20 72.8 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CBZ55665.1 - 1.1e-12 47.4 0.0 1.5e-12 47.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 CBZ55665.1 - 4.4e-08 32.7 0.0 9.7e-08 31.6 0.0 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 CBZ55665.1 - 0.00022 21.1 0.0 0.00028 20.8 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 CBZ55665.1 - 0.00099 18.3 0.0 0.0012 18.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region FeoB_N PF02421.13 CBZ55665.1 - 0.14 11.3 0.3 1.5 8.0 0.2 2.1 1 1 0 1 1 1 0 Ferrous iron transport protein B DUF258 PF03193.11 CBZ55665.1 - 0.56 9.3 0.0 0.56 9.3 0.0 2.0 3 0 0 3 3 3 0 Protein of unknown function, DUF258 AAA_13 PF13166.1 CBZ55666.1 - 0.09 11.2 8.9 0.15 10.4 6.1 1.2 1 0 0 1 1 1 0 AAA domain TIP120 PF08623.5 CBZ55666.1 - 0.91 9.0 4.6 0.38 10.3 0.1 2.3 2 1 1 3 3 3 0 TATA-binding protein interacting (TIP20) Baculo_PEP_C PF04513.7 CBZ55666.1 - 0.92 9.3 18.4 1.8 8.3 4.8 2.4 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Prominin PF05478.6 CBZ55666.1 - 2.8 5.3 10.1 5.1 4.4 7.0 1.3 1 0 0 1 1 1 0 Prominin V_ATPase_I PF01496.14 CBZ55666.1 - 6.1 4.5 5.6 11 3.6 3.9 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family MCM PF00493.18 CBZ55667.1 - 6.5e-122 406.4 0.0 1.2e-121 405.5 0.0 1.4 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 CBZ55667.1 - 3.6e-12 46.8 0.0 2.6e-11 44.0 0.0 2.5 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 CBZ55667.1 - 1.9e-06 27.1 0.1 5.1e-05 22.5 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 CBZ55667.1 - 4e-05 23.3 0.0 0.00015 21.5 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 CBZ55667.1 - 0.00055 19.5 0.0 0.0012 18.4 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 CBZ55667.1 - 0.0085 15.5 0.0 0.85 9.0 0.0 2.3 2 0 0 2 2 2 1 Sigma-54 interaction domain BCDHK_Adom3 PF10436.4 CBZ55669.1 - 1.8e-17 63.3 0.0 2.3e-16 59.7 0.0 2.0 1 1 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 CBZ55669.1 - 2.2e-10 40.2 0.0 0.0029 17.2 0.0 3.4 3 0 0 3 3 3 3 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase zf-CCCH PF00642.19 CBZ55671.1 - 1.5e-13 50.0 15.2 1e-05 25.0 0.4 3.6 3 0 0 3 3 3 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) PAM2 PF07145.10 CBZ55671.1 - 0.0026 17.1 0.2 0.068 12.6 0.1 2.8 2 0 0 2 2 2 1 Ataxin-2 C-terminal region ADK_lid PF05191.9 CBZ55671.1 - 0.011 15.4 0.3 0.075 12.7 0.0 2.2 2 0 0 2 2 2 0 Adenylate kinase, active site lid DUF4448 PF14610.1 CBZ55672.1 - 0.36 10.2 0.3 0.74 9.2 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4448) AA_permease_2 PF13520.1 CBZ55672.1 - 7.1 5.0 0.0 11 4.4 0.0 1.1 1 0 0 1 1 1 0 Amino acid permease MS_channel PF00924.13 CBZ55673.1 - 3.4e-08 33.0 1.8 5.3e-08 32.4 1.2 1.3 1 0 0 1 1 1 1 Mechanosensitive ion channel zf-C3HC4_3 PF13920.1 CBZ55674.1 - 5.4e-10 38.7 7.3 1e-09 37.8 5.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBZ55674.1 - 0.0051 16.5 8.9 0.011 15.5 6.2 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 CBZ55674.1 - 0.018 15.0 10.9 0.038 14.0 7.5 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CBZ55674.1 - 0.65 9.8 10.3 1.3 8.9 7.1 1.5 1 0 0 1 1 1 0 Ring finger domain DUF2039 PF10217.4 CBZ55674.1 - 1.3 9.0 4.3 56 3.8 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2039) Flavodoxin_1 PF00258.20 CBZ55675.1 - 1.3e-17 64.1 0.9 5.8e-17 62.0 0.0 2.5 2 1 1 3 3 3 1 Flavodoxin NAD_binding_1 PF00175.16 CBZ55675.1 - 2.2e-16 60.3 0.1 9.7e-16 58.2 0.0 2.1 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain FAD_binding_1 PF00667.15 CBZ55675.1 - 0.025 14.0 0.0 0.11 11.9 0.0 1.9 2 0 0 2 2 2 0 FAD binding domain NAD_binding_6 PF08030.7 CBZ55675.1 - 0.058 13.3 0.0 0.86 9.5 0.0 2.5 3 0 0 3 3 3 0 Ferric reductase NAD binding domain Flavodoxin_NdrI PF07972.6 CBZ55675.1 - 0.12 12.2 0.0 0.38 10.6 0.0 1.8 2 0 0 2 2 2 0 NrdI Flavodoxin like SIS_2 PF13580.1 CBZ55675.1 - 0.18 11.5 0.0 0.51 10.0 0.0 1.7 1 0 0 1 1 1 0 SIS domain FtsJ PF01728.14 CBZ55676.1 - 5.5e-12 46.0 0.0 1e-11 45.1 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase S4 PF01479.20 CBZ55676.1 - 6.6e-05 22.2 0.1 0.00013 21.2 0.1 1.5 1 0 0 1 1 1 1 S4 domain Methyltransf_26 PF13659.1 CBZ55676.1 - 0.0021 18.0 0.2 0.012 15.6 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 CBZ55676.1 - 0.0026 18.3 0.2 0.0071 16.9 0.1 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CBZ55676.1 - 0.024 15.1 0.1 0.066 13.7 0.1 1.8 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.1 CBZ55676.1 - 0.06 13.0 0.0 0.15 11.7 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain RNA_pol_Rpc4 PF05132.9 CBZ55678.1 - 1e-07 31.9 4.4 4.7e-07 29.8 0.0 3.5 3 1 1 4 4 4 1 RNA polymerase III RPC4 TIP49 PF06068.8 CBZ55679.1 - 2.7e-156 520.2 3.8 1e-99 334.0 0.1 2.0 1 1 1 2 2 2 2 TIP49 C-terminus AAA PF00004.24 CBZ55679.1 - 9.1e-10 38.8 0.1 1.7e-05 24.9 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 CBZ55679.1 - 2.8e-06 27.4 0.0 9.7e-06 25.6 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.7 CBZ55679.1 - 3e-06 26.4 0.3 0.00016 20.7 0.0 2.8 3 0 0 3 3 3 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 CBZ55679.1 - 9.2e-06 25.8 0.1 0.08 13.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.9 CBZ55679.1 - 0.00078 19.1 0.0 0.056 13.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 CBZ55679.1 - 0.0015 17.7 0.4 0.04 13.0 0.1 2.5 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI DBI_PRT PF02277.12 CBZ55679.1 - 0.0031 16.6 0.6 0.0057 15.7 0.4 1.4 1 0 0 1 1 1 1 Phosphoribosyltransferase AAA_23 PF13476.1 CBZ55679.1 - 0.0037 17.6 0.0 0.0061 16.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 CBZ55679.1 - 0.0039 16.8 0.0 0.01 15.5 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_25 PF13481.1 CBZ55679.1 - 0.006 16.0 0.0 0.01 15.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.21 CBZ55679.1 - 0.0067 15.9 0.2 3.3 7.1 0.0 2.7 2 0 0 2 2 2 2 Sigma-54 interaction domain IstB_IS21 PF01695.12 CBZ55679.1 - 0.009 15.4 0.1 0.061 12.7 0.1 2.0 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_17 PF13207.1 CBZ55679.1 - 0.032 15.0 0.0 0.074 13.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 CBZ55679.1 - 0.035 13.9 0.0 0.096 12.5 0.0 1.7 2 0 0 2 2 1 0 AAA domain AAA_29 PF13555.1 CBZ55679.1 - 0.037 13.5 0.1 0.078 12.5 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AFG1_ATPase PF03969.11 CBZ55679.1 - 0.062 12.1 0.6 0.44 9.3 0.1 2.1 2 0 0 2 2 2 0 AFG1-like ATPase PhoH PF02562.11 CBZ55679.1 - 0.07 12.3 0.3 0.14 11.3 0.2 1.4 1 0 0 1 1 1 0 PhoH-like protein ResIII PF04851.10 CBZ55679.1 - 0.14 12.0 0.1 0.72 9.6 0.1 2.0 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit 2-oxoacid_dh PF00198.18 CBZ55680.1 - 2.1e-79 266.0 0.1 2.8e-79 265.6 0.0 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 CBZ55680.1 - 7.3e-20 70.3 0.5 7.3e-20 70.3 0.4 1.8 2 0 0 2 2 2 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.1 CBZ55680.1 - 1.7e-06 27.5 4.1 0.00074 19.1 0.0 2.8 2 1 1 3 3 3 2 Biotin-lipoyl like HlyD_2 PF12700.2 CBZ55680.1 - 0.00062 19.0 0.3 0.016 14.3 0.0 2.3 2 1 1 3 3 3 1 HlyD family secretion protein HlyD_3 PF13437.1 CBZ55680.1 - 0.0024 18.1 0.2 0.64 10.3 0.0 2.3 1 1 1 2 2 2 2 HlyD family secretion protein RnfC_N PF13375.1 CBZ55680.1 - 0.0083 15.8 0.0 0.024 14.3 0.0 1.8 1 0 0 1 1 1 1 RnfC Barrel sandwich hybrid domain HlyD PF00529.15 CBZ55680.1 - 0.017 14.4 2.8 0.092 12.0 0.0 2.5 2 1 1 3 3 3 0 HlyD family secretion protein tRNA-synt_2c PF01411.14 CBZ55681.1 - 1e-200 667.7 0.0 1.3e-200 667.3 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.9 CBZ55681.1 - 1.7e-15 56.5 0.1 4.1e-15 55.3 0.1 1.7 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain zf-RING-like PF08746.6 CBZ55682.1 - 0.015 15.3 0.3 0.015 15.3 0.2 2.0 2 0 0 2 2 2 0 RING-like domain Prok-RING_1 PF14446.1 CBZ55682.1 - 0.076 12.7 7.0 0.14 11.8 2.7 2.5 2 1 0 2 2 2 0 Prokaryotic RING finger family 1 FANCL_C PF11793.3 CBZ55682.1 - 0.11 12.4 0.7 0.41 10.6 0.5 2.0 1 1 0 1 1 1 0 FANCL C-terminal domain MogR_DNAbind PF12181.3 CBZ55682.1 - 0.15 11.8 0.0 0.23 11.2 0.0 1.2 1 0 0 1 1 1 0 DNA binding domain of the motility gene repressor (MogR) Methyltransf_18 PF12847.2 CBZ55683.1 - 5.4e-13 49.4 0.1 1.7e-12 47.8 0.0 1.8 3 0 0 3 3 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CBZ55683.1 - 1.1e-12 47.7 0.0 2.3e-12 46.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 CBZ55683.1 - 4.1e-11 42.9 0.0 8.1e-11 41.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 CBZ55683.1 - 3.9e-10 39.3 0.0 6.3e-10 38.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.7 CBZ55683.1 - 7.7e-10 39.1 0.0 2.1e-09 37.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 CBZ55683.1 - 1.2e-05 24.7 0.1 2.3e-05 23.8 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.1 CBZ55683.1 - 3.8e-05 23.4 0.0 6.2e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CBZ55683.1 - 4.4e-05 23.7 0.0 0.00015 22.1 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain PRMT5 PF05185.11 CBZ55683.1 - 5.4e-05 22.2 0.0 7.8e-05 21.7 0.0 1.2 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_9 PF08003.6 CBZ55683.1 - 0.00016 20.5 0.0 0.00024 19.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_12 PF08242.7 CBZ55683.1 - 0.0012 19.2 0.0 0.0023 18.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 CBZ55683.1 - 0.0022 17.5 0.0 0.0039 16.7 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CMAS PF02353.15 CBZ55683.1 - 0.0023 17.0 0.0 0.0035 16.4 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_16 PF10294.4 CBZ55683.1 - 0.003 17.0 0.1 0.0048 16.3 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Ubie_methyltran PF01209.13 CBZ55683.1 - 0.0031 16.6 0.0 0.0046 16.0 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family DOT1 PF08123.8 CBZ55683.1 - 0.0035 16.6 0.1 0.0096 15.2 0.0 1.7 1 1 1 2 2 2 1 Histone methylation protein DOT1 UPF0020 PF01170.13 CBZ55683.1 - 0.0046 16.5 0.0 0.0084 15.7 0.0 1.4 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_32 PF13679.1 CBZ55683.1 - 0.013 15.1 0.0 0.024 14.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_24 PF13578.1 CBZ55683.1 - 0.014 16.1 0.0 0.032 15.0 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Cons_hypoth95 PF03602.10 CBZ55683.1 - 0.032 13.6 0.0 0.062 12.6 0.0 1.5 1 1 0 1 1 1 0 Conserved hypothetical protein 95 Methyltransf_3 PF01596.12 CBZ55683.1 - 0.081 11.9 0.1 0.16 11.0 0.1 1.5 1 1 0 1 1 1 0 O-methyltransferase MMR_HSR1 PF01926.18 CBZ55684.1 - 3e-11 43.2 0.0 7.1e-10 38.8 0.0 2.3 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 CBZ55684.1 - 6.9e-06 25.4 0.2 0.12 11.6 0.0 2.6 2 1 1 3 3 3 2 Ferrous iron transport protein B GTP_EFTU PF00009.22 CBZ55684.1 - 0.00036 20.0 0.0 0.88 8.9 0.0 2.1 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 CBZ55684.1 - 0.0063 16.3 0.2 5.1 6.8 0.1 3.0 2 1 1 3 3 3 1 Dynamin family AAA_29 PF13555.1 CBZ55684.1 - 0.016 14.7 0.0 0.027 13.9 0.0 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF258 PF03193.11 CBZ55684.1 - 0.042 13.0 0.0 0.068 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF258 GHL13 PF14883.1 CBZ55685.1 - 0.057 12.5 0.4 4.5 6.3 0.0 2.2 2 0 0 2 2 2 0 Hypothetical glycosyl hydrolase family 13 Peptidase_S9 PF00326.16 CBZ55686.1 - 6e-11 41.9 0.0 3.6e-09 36.1 0.0 2.4 2 0 0 2 2 2 2 Prolyl oligopeptidase family Diphthamide_syn PF01866.12 CBZ55687.1 - 1.4e-15 57.3 0.2 1.5e-07 30.9 0.0 2.1 2 0 0 2 2 2 2 Putative diphthamide synthesis protein WD40 PF00400.27 CBZ55688.1 - 2.5e-23 81.0 18.6 3.4e-05 23.5 0.0 11.3 13 1 0 13 13 13 7 WD domain, G-beta repeat EF-hand_6 PF13405.1 CBZ55688.1 - 0.18 11.7 0.3 6 7.0 0.1 2.6 2 0 0 2 2 2 0 EF-hand domain Beta-Casp PF10996.3 CBZ55689.1 - 0.0011 18.9 0.0 0.002 18.0 0.0 1.4 1 0 0 1 1 1 1 Beta-Casp domain DapB_C PF05173.9 CBZ55689.1 - 2 8.2 3.9 37 4.0 0.0 3.4 4 0 0 4 4 4 0 Dihydrodipicolinate reductase, C-terminus tRNA-synt_2b PF00587.20 CBZ55690.1 - 3.9e-26 91.6 0.0 6.8e-25 87.6 0.0 2.2 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 CBZ55690.1 - 0.065 13.1 0.1 0.17 11.8 0.0 1.7 1 1 0 1 1 1 0 Anticodon binding domain CDC45 PF02724.9 CBZ55690.1 - 0.57 8.1 2.0 0.79 7.6 1.4 1.2 1 0 0 1 1 1 0 CDC45-like protein Nucleo_P87 PF07267.6 CBZ55690.1 - 2.6 6.6 2.7 3.5 6.1 1.9 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 HSP70 PF00012.15 CBZ55693.1 - 2.4e-111 372.5 0.0 3.2e-103 345.7 0.0 2.1 2 0 0 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.8 CBZ55693.1 - 1.4e-05 23.8 0.0 0.00015 20.5 0.0 2.3 2 1 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.11 CBZ55693.1 - 0.00038 20.1 0.0 0.00076 19.1 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Ribos_L4_asso_C PF14374.1 CBZ55693.1 - 0.054 13.3 0.7 0.13 12.1 0.5 1.6 1 0 0 1 1 1 0 60S ribosomal protein L4 C-terminal domain zf-RanBP PF00641.13 CBZ55694.1 - 1.3e-13 49.8 22.0 2.1e-07 29.8 4.0 2.3 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others DZR PF12773.2 CBZ55694.1 - 0.86 9.4 10.0 2.2 8.1 1.7 2.0 1 1 1 2 2 2 0 Double zinc ribbon Apt1 PF10351.4 CBZ55694.1 - 5.2 5.8 5.5 7 5.3 3.8 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain F_actin_cap_B PF01115.12 CBZ55695.1 - 2.5e-72 242.9 0.0 3e-72 242.7 0.0 1.1 1 0 0 1 1 1 1 F-actin capping protein, beta subunit Actin PF00022.14 CBZ55696.1 - 9.9e-94 313.9 0.0 1.1e-93 313.7 0.0 1.0 1 0 0 1 1 1 1 Actin dTMP_synthase PF02593.9 CBZ55696.1 - 0.13 11.5 0.0 0.46 9.8 0.0 1.7 2 0 0 2 2 2 0 Thymidylate synthase DUF3273 PF11677.3 CBZ55697.1 - 1.3e-77 260.6 13.1 1.8e-77 260.1 9.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3273) E1-E2_ATPase PF00122.15 CBZ55698.1 - 2.5e-27 95.3 0.2 4.6e-27 94.5 0.2 1.3 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 CBZ55698.1 - 1.8e-14 54.6 0.0 0.00023 21.6 0.0 4.1 4 0 0 4 4 4 3 haloacid dehalogenase-like hydrolase HAD PF12710.2 CBZ55698.1 - 3.2e-10 40.5 0.0 4.2e-07 30.3 0.0 3.1 3 1 0 3 3 3 2 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 CBZ55698.1 - 0.00085 19.2 0.0 0.0023 17.8 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit TPMT PF05724.6 CBZ55698.1 - 0.037 13.4 0.0 0.071 12.5 0.0 1.4 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) Hydrolase_3 PF08282.7 CBZ55698.1 - 4.1 6.9 0.1 51 3.3 0.0 2.2 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Acetyltransf_1 PF00583.19 CBZ55699.1 - 7.2e-07 29.1 0.0 1.5e-06 28.1 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 CBZ55699.1 - 0.0038 17.3 0.0 0.0082 16.2 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 CBZ55699.1 - 0.064 13.3 0.0 0.36 10.9 0.0 2.2 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain GNAT_acetyltr_2 PF13718.1 CBZ55699.1 - 0.13 11.6 0.0 0.22 10.8 0.0 1.3 1 0 0 1 1 1 0 GNAT acetyltransferase 2 PTH2 PF01981.11 CBZ55700.1 - 1.6e-06 27.7 0.0 4.8e-06 26.2 0.0 1.8 2 0 0 2 2 2 1 Peptidyl-tRNA hydrolase PTH2 LEA_3 PF03242.8 CBZ55700.1 - 0.13 12.4 0.1 0.31 11.2 0.1 1.5 1 0 0 1 1 1 0 Late embryogenesis abundant protein AMP-binding PF00501.23 CBZ55701.1 - 3.2e-21 75.2 0.1 5.7e-11 41.4 0.0 2.2 2 0 0 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.1 CBZ55701.1 - 1.2e-11 45.3 0.3 3.7e-11 43.8 0.0 2.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Ank_2 PF12796.2 CBZ55703.1 - 1e-26 93.1 0.2 8.7e-14 51.6 0.2 3.4 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.25 CBZ55703.1 - 1.1e-23 81.7 6.5 1.6e-05 24.4 0.1 6.2 6 1 1 7 7 7 4 Ankyrin repeat Ank_3 PF13606.1 CBZ55703.1 - 4.1e-20 69.8 0.1 0.00031 20.6 0.1 6.0 6 0 0 6 6 6 4 Ankyrin repeat Ank_4 PF13637.1 CBZ55703.1 - 7.8e-20 70.8 0.1 5.4e-07 29.9 0.0 4.5 4 1 0 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 CBZ55703.1 - 7.2e-17 61.0 3.3 1.9e-05 24.7 0.1 4.9 4 1 0 4 4 4 3 Ankyrin repeats (many copies) DEAD PF00270.24 CBZ55704.1 - 3.1e-41 140.6 0.1 3.9e-40 137.1 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CBZ55704.1 - 1.4e-21 76.1 0.0 3.1e-21 75.0 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF1253 PF06862.7 CBZ55704.1 - 2.4e-05 22.9 0.0 0.006 15.0 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF1253) AAA_22 PF13401.1 CBZ55704.1 - 0.19 11.8 1.8 0.56 10.3 0.1 2.6 3 0 0 3 3 3 0 AAA domain CS PF04969.11 CBZ55705.1 - 2e-11 44.2 0.0 2.8e-11 43.8 0.0 1.2 1 0 0 1 1 1 1 CS domain Acetyltransf_1 PF00583.19 CBZ55706.1 - 7.4e-07 29.1 0.1 1.8e-06 27.8 0.1 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 CBZ55706.1 - 1.8e-05 24.7 0.0 4.2e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 CBZ55706.1 - 0.00019 21.3 0.3 0.00047 20.0 0.1 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 CBZ55706.1 - 0.041 13.6 0.0 0.1 12.3 0.0 1.6 1 0 0 1 1 1 0 FR47-like protein UPF0560 PF10577.4 CBZ55707.1 - 0.069 11.3 4.6 0.086 11.0 3.2 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Kri1_C PF12936.2 CBZ55708.1 - 9.4e-29 99.2 0.7 9.4e-29 99.2 0.5 3.1 2 0 0 2 2 2 1 KRI1-like family C-terminal Kri1 PF05178.7 CBZ55708.1 - 5e-22 78.0 6.3 5e-22 78.0 4.3 4.4 3 3 0 3 3 3 1 KRI1-like family ZZ PF00569.12 CBZ55708.1 - 1.1e-05 24.8 5.4 2.9e-05 23.5 3.4 1.9 2 0 0 2 2 2 1 Zinc finger, ZZ type zf-UBR PF02207.15 CBZ55708.1 - 0.41 10.4 7.1 0.2 11.4 3.1 1.8 2 0 0 2 2 2 0 Putative zinc finger in N-recognin (UBR box) EF1_GNE PF00736.14 CBZ55709.1 - 3.2e-30 103.6 4.3 5.9e-30 102.8 3.0 1.4 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain DNA_pol3_a_NII PF11490.3 CBZ55709.1 - 0.74 9.4 8.2 2.9 7.5 1.3 2.2 2 0 0 2 2 2 0 DNA polymerase III polC-type N-terminus II Rpp20 PF12328.3 CBZ55709.1 - 6.1 6.5 11.1 4.7 6.8 4.3 2.1 2 0 0 2 2 2 0 Rpp20 subunit of nuclear RNase MRP and P PBP1_TM PF14812.1 CBZ55709.1 - 6.1 7.2 12.3 3.9 7.8 4.2 2.3 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Sigma70_ner PF04546.8 CBZ55709.1 - 6.3 6.3 12.9 0.5 9.9 4.0 2.0 2 0 0 2 2 2 0 Sigma-70, non-essential region Pyr_redox_2 PF07992.9 CBZ55710.1 - 1.4e-35 123.0 0.1 2.1e-35 122.4 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.17 CBZ55710.1 - 1.6e-30 105.3 0.0 6.2e-30 103.4 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.22 CBZ55710.1 - 4.9e-15 55.6 5.3 3.8e-12 46.4 0.1 2.7 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 CBZ55710.1 - 1.7e-09 38.0 0.0 3.3e-09 37.0 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 CBZ55710.1 - 3.7e-08 32.8 3.8 7.9e-08 31.7 2.6 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.19 CBZ55710.1 - 1.6e-07 30.5 4.0 2.9e-06 26.4 0.1 3.5 3 1 1 4 4 4 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 CBZ55710.1 - 3.1e-05 22.9 14.6 0.0025 16.7 6.9 3.2 2 1 0 2 2 2 1 FAD binding domain GIDA PF01134.17 CBZ55710.1 - 6.5e-05 21.9 2.5 6.5e-05 21.9 1.7 2.2 3 0 0 3 3 3 1 Glucose inhibited division protein A HI0933_like PF03486.9 CBZ55710.1 - 0.00034 19.1 1.3 0.00034 19.1 0.9 1.7 2 0 0 2 2 2 1 HI0933-like protein XdhC_C PF13478.1 CBZ55710.1 - 0.0016 18.7 0.2 0.14 12.4 0.0 2.5 2 0 0 2 2 2 1 XdhC Rossmann domain 2-Hacid_dh_C PF02826.14 CBZ55710.1 - 0.0054 15.8 0.4 0.76 8.9 0.0 2.7 2 1 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Thi4 PF01946.12 CBZ55710.1 - 0.0055 15.8 1.0 0.012 14.7 0.7 1.4 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.1 CBZ55710.1 - 0.0081 16.1 3.0 0.0081 16.1 2.1 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 CBZ55710.1 - 0.011 14.7 0.0 0.023 13.6 0.0 1.5 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) NAD_Gly3P_dh_N PF01210.18 CBZ55710.1 - 0.031 13.9 1.8 0.79 9.4 0.0 2.4 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_7 PF13241.1 CBZ55710.1 - 0.073 13.3 0.1 10 6.4 0.0 2.6 2 0 0 2 2 2 0 Putative NAD(P)-binding UDPG_MGDP_dh_N PF03721.9 CBZ55710.1 - 0.14 11.5 0.1 1.4 8.2 0.0 2.4 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain AlaDh_PNT_C PF01262.16 CBZ55710.1 - 0.21 11.1 4.3 0.86 9.1 0.0 2.3 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.13 CBZ55710.1 - 0.68 9.5 6.9 2.7 7.6 0.2 2.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain zf-CCCH PF00642.19 CBZ55711.1 - 5.2e-09 35.5 22.8 6.7e-05 22.4 1.7 4.2 4 1 0 4 4 4 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) CKS PF01111.14 CBZ55713.1 - 6.6e-20 70.7 0.1 1.4e-19 69.6 0.0 1.6 2 0 0 2 2 2 1 Cyclin-dependent kinase regulatory subunit DUF410 PF04190.8 CBZ55714.1 - 1.3e-25 90.4 0.0 4e-25 88.8 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF410) cNMP_binding PF00027.24 CBZ55715.1 - 2.4e-90 296.5 4.3 5.9e-19 67.6 0.0 6.5 6 0 0 6 6 6 6 Cyclic nucleotide-binding domain EF-hand_6 PF13405.1 CBZ55715.1 - 0.00037 20.1 3.7 0.85 9.6 0.1 4.0 4 0 0 4 4 4 2 EF-hand domain EF-hand_7 PF13499.1 CBZ55715.1 - 0.00079 19.5 2.4 1.2 9.3 0.1 4.4 5 0 0 5 5 5 1 EF-hand domain pair EF-hand_1 PF00036.27 CBZ55715.1 - 0.0055 15.9 4.6 0.025 13.8 0.2 3.1 3 0 0 3 3 3 1 EF hand FlaC_arch PF05377.6 CBZ55716.1 - 0.12 12.2 7.2 0.17 11.8 0.1 3.6 4 0 0 4 4 4 0 Flagella accessory protein C (FlaC) DUF972 PF06156.8 CBZ55716.1 - 0.19 12.0 16.6 0.81 10.0 0.3 4.4 3 2 1 5 5 5 0 Protein of unknown function (DUF972) CorA PF01544.13 CBZ55716.1 - 0.41 9.6 5.6 0.3 10.0 0.0 3.0 3 0 0 3 3 3 0 CorA-like Mg2+ transporter protein TSC22 PF01166.13 CBZ55716.1 - 0.75 9.8 10.3 7.1 6.6 0.6 4.0 4 0 0 4 4 4 0 TSC-22/dip/bun family IncA PF04156.9 CBZ55716.1 - 1.3 8.5 23.9 3.2 7.3 1.6 4.0 4 0 0 4 4 4 0 IncA protein SF-assemblin PF06705.6 CBZ55716.1 - 1.4 7.9 11.0 1.5 7.9 0.2 3.5 4 0 0 4 4 4 0 SF-assemblin/beta giardin AP2 PF00847.15 CBZ55717.1 - 2e-20 72.7 32.2 7.3e-09 35.6 0.3 5.6 5 0 0 5 5 5 4 AP2 domain ACDC PF14733.1 CBZ55717.1 - 2.2e-06 27.6 0.0 5e-06 26.5 0.0 1.6 1 1 0 1 1 1 1 AP2-coincident C-terminal Atx10homo_assoc PF09759.4 CBZ55718.1 - 0.00026 20.6 0.0 0.041 13.6 0.0 2.6 2 0 0 2 2 2 2 Spinocerebellar ataxia type 10 protein domain BTB PF00651.26 CBZ55720.1 - 1.3e-14 54.1 0.0 2.7e-14 53.0 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain DUF620 PF04788.7 CBZ55720.1 - 0.11 11.6 0.1 0.18 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF620) Proteasome PF00227.21 CBZ55721.1 - 4.2e-48 163.1 0.0 5.2e-48 162.8 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit LRRC37AB_C PF14914.1 CBZ55722.1 - 0.34 10.3 2.6 0.39 10.1 0.5 2.0 2 0 0 2 2 2 0 LRRC37A/B like protein 1 C-terminal domain Adipogenin PF15202.1 CBZ55722.1 - 6.9 6.6 10.5 1.4 8.8 1.0 2.7 2 0 0 2 2 2 0 Adipogenin Prominin PF05478.6 CBZ55722.1 - 9.3 3.6 15.4 2.5 5.5 6.7 2.2 2 0 0 2 2 2 0 Prominin Baculo_PEP_C PF04513.7 CBZ55724.1 - 0.27 11.0 2.3 0.36 10.6 0.4 2.1 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus SF-assemblin PF06705.6 CBZ55725.1 - 6.3e-61 205.6 32.0 7.3e-61 205.4 22.2 1.0 1 0 0 1 1 1 1 SF-assemblin/beta giardin TPR_2 PF07719.12 CBZ55725.1 - 0.44 10.5 2.3 5.4 7.1 0.5 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat SDH_alpha PF03313.10 CBZ55725.1 - 1.2 8.0 10.0 1.1 8.2 2.3 2.1 1 1 1 2 2 2 0 Serine dehydratase alpha chain TPR_11 PF13414.1 CBZ55725.1 - 2.1 8.0 5.0 1.7 8.3 1.2 2.5 2 1 0 2 2 2 0 TPR repeat NPV_P10 PF05531.7 CBZ55725.1 - 5.6 7.2 9.2 15 5.9 0.2 3.5 2 1 2 4 4 4 0 Nucleopolyhedrovirus P10 protein RabGAP-TBC PF00566.13 CBZ55726.1 - 1.8e-61 207.3 1.7 2.6e-61 206.8 1.2 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Ribosomal_S9 PF00380.14 CBZ55728.1 - 1.8e-36 125.0 0.0 2.3e-36 124.7 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S9/S16 MutS_V PF00488.16 CBZ55729.1 - 4e-14 52.6 0.0 2.1e-08 33.8 0.0 3.3 3 0 0 3 3 3 3 MutS domain V MutS_I PF01624.15 CBZ55729.1 - 4.5e-05 23.4 0.0 0.0001 22.3 0.0 1.5 1 0 0 1 1 1 1 MutS domain I GIY-YIG PF01541.19 CBZ55729.1 - 0.003 17.8 0.0 0.006 16.9 0.0 1.4 1 0 0 1 1 1 1 GIY-YIG catalytic domain AAA_29 PF13555.1 CBZ55729.1 - 0.032 13.7 0.0 0.083 12.4 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.1 CBZ55729.1 - 0.13 12.5 0.0 0.34 11.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain Neurochondrin PF05536.6 CBZ55730.1 - 2.6e-07 29.3 0.8 0.0037 15.6 0.0 2.8 3 0 0 3 3 3 2 Neurochondrin KAR9 PF08580.5 CBZ55730.1 - 0.0095 14.2 12.3 0.015 13.6 8.5 1.2 1 0 0 1 1 1 1 Yeast cortical protein KAR9 SOBP PF15279.1 CBZ55730.1 - 0.01 16.2 6.2 0.03 14.7 4.3 1.8 1 0 0 1 1 1 0 Sine oculis-binding protein Sec3_C PF09763.4 CBZ55730.1 - 0.052 11.6 6.5 0.11 10.6 4.5 1.4 1 0 0 1 1 1 0 Exocyst complex component Sec3 DUF1798 PF08807.5 CBZ55730.1 - 0.067 12.9 0.2 0.18 11.5 0.1 1.6 1 0 0 1 1 1 0 Bacterial domain of unknown function (DUF1798) Pex14_N PF04695.8 CBZ55730.1 - 0.1 12.6 11.1 0.48 10.4 6.3 2.9 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Alba PF01918.16 CBZ55731.1 - 5e-05 22.8 0.0 8.2e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 Alba Tyr_Deacylase PF02580.11 CBZ55732.1 - 1.9e-39 134.9 0.0 2.5e-39 134.5 0.0 1.2 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase GTP_EFTU PF00009.22 CBZ55734.1 - 1.8e-46 157.9 0.0 3.1e-46 157.1 0.0 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.19 CBZ55734.1 - 1.2e-15 57.1 0.0 2.4e-14 52.9 0.0 2.3 1 1 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.1 CBZ55734.1 - 3.8e-15 55.4 0.0 9.9e-15 54.1 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.18 CBZ55734.1 - 0.001 19.0 0.0 0.0018 18.1 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.20 CBZ55734.1 - 0.028 14.5 0.0 0.059 13.4 0.0 1.6 1 0 0 1 1 1 0 Elongation factor Tu domain 2 Miro PF08477.8 CBZ55734.1 - 0.082 13.4 0.0 0.15 12.5 0.0 1.4 1 0 0 1 1 1 0 Miro-like protein Aminotran_5 PF00266.14 CBZ55735.1 - 3.9e-37 127.8 0.0 1.2e-17 63.7 0.0 2.2 2 1 0 2 2 2 2 Aminotransferase class-V Mito_carr PF00153.22 CBZ55736.1 - 0.0005 19.7 3.5 5.4 6.8 0.0 3.9 4 0 0 4 4 4 3 Mitochondrial carrier protein SNAP PF14938.1 CBZ55737.1 - 1.1e-84 283.9 4.4 1.3e-84 283.7 3.1 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_19 PF14559.1 CBZ55737.1 - 0.00023 21.4 6.2 0.013 15.7 0.2 3.7 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_10 PF13374.1 CBZ55737.1 - 0.01 15.7 1.1 0.37 10.8 0.2 3.0 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.1 CBZ55737.1 - 0.027 14.3 9.3 0.84 9.6 0.2 3.8 5 0 0 5 5 5 0 Tetratricopeptide repeat NSF PF02071.15 CBZ55737.1 - 0.11 13.1 6.4 19 6.3 0.0 4.8 4 0 0 4 4 3 0 Aromatic-di-Alanine (AdAR) repeat TPR_7 PF13176.1 CBZ55737.1 - 0.15 11.8 12.1 1 9.2 0.1 5.4 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_14 PF13428.1 CBZ55737.1 - 0.24 12.1 12.7 0.28 11.9 0.1 4.8 4 2 1 5 5 5 0 Tetratricopeptide repeat TPR_2 PF07719.12 CBZ55737.1 - 1.6 8.8 13.3 1.8 8.7 0.1 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.1 CBZ55737.1 - 2.9 8.5 10.8 4.9 7.8 0.1 4.5 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_16 PF13432.1 CBZ55737.1 - 5.9 7.6 16.5 6.6 7.5 0.2 4.3 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.23 CBZ55737.1 - 6.6 6.5 9.7 45 3.8 0.0 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat Myosin_head PF00063.16 CBZ55738.1 - 6.5e-07 27.7 0.0 0.0014 16.7 0.0 2.8 2 1 0 2 2 2 2 Myosin head (motor domain) AAA_22 PF13401.1 CBZ55738.1 - 0.086 12.9 0.0 0.34 11.0 0.0 2.0 1 0 0 1 1 1 0 AAA domain Sigma70_ner PF04546.8 CBZ55738.1 - 1.6 8.2 2.5 3 7.4 1.7 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region HAMP PF00672.20 CBZ55739.1 - 1.2 9.4 5.8 0.12 12.5 0.7 1.9 2 0 0 2 2 2 0 HAMP domain Borrelia_P13 PF05628.7 CBZ55740.1 - 0.06 13.1 0.5 0.095 12.5 0.4 1.3 1 0 0 1 1 1 0 Borrelia membrane protein P13 Pkinase PF00069.20 CBZ55741.1 - 4.2e-61 206.3 0.0 6.3e-61 205.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ55741.1 - 4e-38 130.9 0.0 7e-38 130.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_1 PF00036.27 CBZ55741.1 - 1.7e-36 120.7 8.9 3.8e-06 25.8 0.2 6.6 6 0 0 6 6 6 6 EF hand EF-hand_7 PF13499.1 CBZ55741.1 - 1.5e-32 111.5 6.4 1.1e-11 44.6 0.1 4.4 4 1 0 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.1 CBZ55741.1 - 2.1e-29 99.5 13.0 2.3e-06 26.7 0.0 6.3 7 0 0 7 7 7 5 EF hand EF-hand_6 PF13405.1 CBZ55741.1 - 2.8e-26 88.9 11.9 0.0003 20.4 0.1 6.7 6 0 0 6 6 6 5 EF-hand domain EF-hand_8 PF13833.1 CBZ55741.1 - 8.3e-25 86.1 16.4 9e-09 34.8 0.2 6.5 4 2 2 6 6 6 6 EF-hand domain pair SPARC_Ca_bdg PF10591.4 CBZ55741.1 - 3.5e-10 39.9 0.1 0.0004 20.3 0.0 3.8 2 1 1 3 3 3 2 Secreted protein acidic and rich in cysteine Ca binding region Kdo PF06293.9 CBZ55741.1 - 7.4e-06 25.1 0.0 1.6e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family EF-hand_4 PF12763.2 CBZ55741.1 - 4.1e-05 23.2 9.0 0.033 13.9 0.0 4.1 2 2 2 4 4 4 2 Cytoskeletal-regulatory complex EF hand Kinase-like PF14531.1 CBZ55741.1 - 0.00035 19.6 0.0 0.00062 18.8 0.0 1.4 1 0 0 1 1 1 1 Kinase-like YrbL-PhoP_reg PF10707.4 CBZ55741.1 - 0.0033 16.7 0.0 0.0068 15.7 0.0 1.5 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL Excalibur PF05901.6 CBZ55741.1 - 0.0045 17.2 1.2 5.8 7.3 0.1 3.6 4 0 0 4 4 3 1 Excalibur calcium-binding domain APH PF01636.18 CBZ55741.1 - 0.039 13.6 0.1 0.2 11.3 0.0 2.2 2 1 0 2 2 2 0 Phosphotransferase enzyme family Choline_kinase PF01633.15 CBZ55741.1 - 0.04 13.4 0.1 0.073 12.6 0.1 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase EF-hand_10 PF14788.1 CBZ55741.1 - 0.072 12.7 2.0 9.5 5.9 0.0 3.9 4 1 0 4 4 4 0 EF hand GNAT_acetyltr_2 PF13718.1 CBZ55742.1 - 2.9e-67 225.7 0.0 1.1e-66 223.8 0.0 2.0 2 1 0 2 2 2 1 GNAT acetyltransferase 2 Helicase_RecD PF05127.9 CBZ55742.1 - 3.9e-58 195.9 0.0 7.9e-58 194.9 0.0 1.5 1 0 0 1 1 1 1 Helicase DUF1726 PF08351.6 CBZ55742.1 - 1.4e-35 120.8 0.1 3.7e-35 119.4 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF1726) tRNA_bind_2 PF13725.1 CBZ55742.1 - 2.6e-24 85.2 0.0 7e-24 83.8 0.0 1.8 1 0 0 1 1 1 1 Possible tRNA binding domain CDC45 PF02724.9 CBZ55742.1 - 0.0044 15.1 9.6 0.0078 14.3 6.6 1.3 1 0 0 1 1 1 1 CDC45-like protein DUF2457 PF10446.4 CBZ55742.1 - 0.0079 14.9 14.6 0.013 14.2 10.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2457) Acetyltransf_7 PF13508.1 CBZ55742.1 - 0.013 15.6 0.0 0.036 14.2 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 CBZ55742.1 - 0.039 13.9 0.0 0.15 12.0 0.0 2.0 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Daxx PF03344.10 CBZ55742.1 - 0.3 9.5 19.8 0.51 8.7 13.7 1.3 1 0 0 1 1 1 0 Daxx Family Nop14 PF04147.7 CBZ55742.1 - 1.5 6.6 21.7 2.6 5.8 15.0 1.3 1 0 0 1 1 1 0 Nop14-like family RRM_6 PF14259.1 CBZ55743.1 - 0.34 10.9 2.0 2 8.4 0.0 2.9 4 0 0 4 4 4 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) PP2C PF00481.16 CBZ55744.1 - 1.5e-33 116.2 0.0 3.6e-33 115.0 0.0 1.6 1 0 0 1 1 1 1 Protein phosphatase 2C DUF4094 PF13334.1 CBZ55744.1 - 0.046 14.1 0.1 1.2 9.6 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4094) SpoU_methylase PF00588.14 CBZ55745.1 - 3.3e-22 78.9 0.1 6.1e-16 58.5 0.0 2.6 2 0 0 2 2 2 2 SpoU rRNA Methylase family NOB1_Zn_bind PF08772.6 CBZ55746.1 - 2.1e-19 69.1 0.1 3.8e-19 68.2 0.1 1.4 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like DZR PF12773.2 CBZ55746.1 - 0.084 12.7 0.1 0.18 11.6 0.1 1.5 1 0 0 1 1 1 0 Double zinc ribbon zinc_ribbon_2 PF13240.1 CBZ55746.1 - 0.094 12.2 0.2 0.2 11.1 0.1 1.5 1 0 0 1 1 1 0 zinc-ribbon domain zf-ribbon_3 PF13248.1 CBZ55746.1 - 0.1 11.8 0.5 0.22 10.7 0.4 1.6 1 0 0 1 1 1 0 zinc-ribbon domain Daxx PF03344.10 CBZ55746.1 - 0.22 9.9 21.1 0.47 8.8 14.6 1.5 1 0 0 1 1 1 0 Daxx Family Nudix_N_2 PF14803.1 CBZ55746.1 - 0.3 10.7 2.4 1.6 8.4 0.1 2.6 2 0 0 2 2 2 0 Nudix N-terminal Nop14 PF04147.7 CBZ55746.1 - 0.53 8.1 24.2 0.72 7.6 16.8 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 CBZ55746.1 - 0.59 8.1 12.7 0.82 7.6 8.8 1.1 1 0 0 1 1 1 0 CDC45-like protein PBP_sp32 PF07222.7 CBZ55746.1 - 0.72 8.9 5.4 84 2.2 6.7 2.0 2 0 0 2 2 2 0 Proacrosin binding protein sp32 YL1 PF05764.8 CBZ55746.1 - 0.77 9.3 18.0 1.5 8.3 12.5 1.4 1 0 0 1 1 1 0 YL1 nuclear protein Prothymosin PF03247.9 CBZ55746.1 - 1.3 9.2 34.6 3.6 7.7 23.9 1.7 1 0 0 1 1 1 0 Prothymosin/parathymosin family VID27 PF08553.5 CBZ55746.1 - 1.5 6.9 12.2 2.1 6.4 8.4 1.1 1 0 0 1 1 1 0 VID27 cytoplasmic protein Mpp10 PF04006.7 CBZ55746.1 - 2.3 6.4 20.4 3.3 5.9 14.2 1.1 1 0 0 1 1 1 0 Mpp10 protein Carboxyl_trans PF01039.17 CBZ55747.1 - 3e-150 500.8 0.0 4.3e-150 500.3 0.0 1.2 1 0 0 1 1 1 1 Carboxyl transferase domain ACC_central PF08326.7 CBZ55747.1 - 2.6e-52 177.9 0.0 1.8e-17 62.7 0.0 4.4 4 1 0 4 4 4 4 Acetyl-CoA carboxylase, central region CPSase_L_D2 PF02786.12 CBZ55747.1 - 4.8e-47 159.9 0.2 1e-46 158.8 0.1 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_chain PF00289.17 CBZ55747.1 - 3.7e-26 91.3 0.0 1e-25 89.9 0.0 1.8 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 CBZ55747.1 - 6.3e-22 77.5 0.0 1.5e-21 76.3 0.0 1.7 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain ATP-grasp_4 PF13535.1 CBZ55747.1 - 4e-13 49.5 0.0 1.2e-12 47.9 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl PF00364.17 CBZ55747.1 - 1.7e-09 37.2 0.7 3.4e-09 36.2 0.0 1.9 2 0 0 2 2 2 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.8 CBZ55747.1 - 6.9e-06 25.5 0.0 1.4e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Biotin_lipoyl_2 PF13533.1 CBZ55747.1 - 0.0034 17.0 0.1 0.026 14.1 0.1 2.5 2 0 0 2 2 2 1 Biotin-lipoyl like ATP-grasp PF02222.17 CBZ55747.1 - 0.016 14.5 0.0 0.035 13.4 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp domain ATP-grasp_3 PF02655.9 CBZ55747.1 - 0.11 12.3 0.0 0.22 11.3 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp domain Pkinase PF00069.20 CBZ55748.1 - 5.2e-28 97.8 0.0 6.3e-27 94.3 0.0 2.5 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ55748.1 - 4.9e-11 42.1 0.0 1.1e-10 41.0 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Abhydrolase_6 PF12697.2 CBZ55749.1 - 2.4e-12 47.2 4.2 7.6e-12 45.6 2.8 1.7 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CBZ55749.1 - 8.9e-10 38.4 0.0 2.2e-09 37.2 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 CBZ55749.1 - 7.7e-06 25.6 0.1 1.4e-05 24.7 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 CBZ55749.1 - 0.00018 20.8 0.0 0.43 9.7 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family DUF1100 PF06500.6 CBZ55749.1 - 0.00072 18.2 0.0 0.0021 16.7 0.0 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF1100) Hydrolase_4 PF12146.3 CBZ55749.1 - 0.0068 16.2 0.0 0.014 15.2 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase Abhydrolase_1 PF00561.15 CBZ55749.1 - 0.015 14.8 0.0 0.26 10.8 0.0 2.2 1 1 0 1 1 1 0 alpha/beta hydrolase fold AXE1 PF05448.7 CBZ55749.1 - 0.025 13.0 0.1 0.2 10.0 0.0 2.2 2 1 0 2 2 2 0 Acetyl xylan esterase (AXE1) PITH PF06201.8 CBZ55750.1 - 1.2e-23 83.5 0.0 1.3e-23 83.4 0.0 1.1 1 0 0 1 1 1 1 PITH domain cEGF PF12662.2 CBZ55751.1 - 1.9e-06 27.3 13.1 0.019 14.5 0.4 4.0 3 0 0 3 3 3 2 Complement Clr-like EGF-like FXa_inhibition PF14670.1 CBZ55751.1 - 8.7e-06 25.7 37.8 0.00036 20.6 6.0 3.5 3 0 0 3 3 3 3 Coagulation Factor Xa inhibitory site EGF PF00008.22 CBZ55751.1 - 0.00029 20.7 35.7 0.0019 18.1 5.9 3.9 3 0 0 3 3 3 2 EGF-like domain hEGF PF12661.2 CBZ55751.1 - 0.0023 17.9 15.1 0.11 12.6 0.6 5.1 3 2 1 4 4 4 3 Human growth factor-like EGF EGF_CA PF07645.10 CBZ55751.1 - 0.0059 16.5 30.5 0.04 13.9 5.0 3.6 3 1 0 3 3 3 2 Calcium-binding EGF domain DUF4366 PF14283.1 CBZ55751.1 - 0.012 15.0 0.2 0.019 14.3 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) Laminin_G_3 PF13385.1 CBZ55752.1 - 6.5e-18 65.4 0.0 9.7e-18 64.8 0.0 1.4 1 1 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Laminin_G_2 PF02210.19 CBZ55752.1 - 0.0001 22.3 0.0 0.00017 21.6 0.0 1.3 1 0 0 1 1 1 1 Laminin G domain WD40 PF00400.27 CBZ55753.1 - 0.2 11.5 2.5 35 4.4 0.1 5.2 6 0 0 6 6 6 0 WD domain, G-beta repeat Thioredoxin PF00085.15 CBZ55755.1 - 4.3e-42 142.0 0.0 6.5e-22 77.1 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_6 PF13848.1 CBZ55755.1 - 5.3e-15 55.7 0.0 2.3e-08 34.0 0.0 4.4 4 0 0 4 4 4 3 Thioredoxin-like domain Thioredoxin_2 PF13098.1 CBZ55755.1 - 5.4e-10 39.4 0.1 3.8e-05 23.8 0.0 3.6 2 2 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_7 PF13899.1 CBZ55755.1 - 8e-08 32.2 0.1 3.2e-05 23.8 0.0 2.8 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_8 PF13905.1 CBZ55755.1 - 7.7e-05 22.7 0.0 0.0051 16.9 0.0 2.8 2 0 0 2 2 2 1 Thioredoxin-like Lectin_C PF00059.16 CBZ55756.1 - 2.4e-07 31.3 0.0 7.2e-07 29.8 0.0 1.8 1 0 0 1 1 1 1 Lectin C-type domain DUF2256 PF10013.4 CBZ55756.1 - 0.07 12.8 0.5 0.24 11.1 0.1 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) WD40 PF00400.27 CBZ55757.1 - 6.1e-54 178.0 15.5 1.8e-10 40.2 0.5 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat Nucleoporin_N PF08801.6 CBZ55757.1 - 0.00074 18.3 0.3 1.2 7.7 0.0 3.7 1 1 3 4 4 4 2 Nup133 N terminal like Nup160 PF11715.3 CBZ55757.1 - 0.011 13.8 1.5 0.87 7.6 0.0 3.1 1 1 1 3 3 3 0 Nucleoporin Nup120/160 Ribosomal_L10 PF00466.15 CBZ55758.1 - 4.6e-21 74.6 0.1 1.3e-20 73.1 0.1 1.7 2 0 0 2 2 2 1 Ribosomal protein L10 Ribosomal_60s PF00428.14 CBZ55758.1 - 3.7e-18 65.6 2.1 8.6e-18 64.5 1.4 1.7 1 0 0 1 1 1 1 60s Acidic ribosomal protein Pkinase PF00069.20 CBZ55759.1 - 2.2e-56 190.8 0.0 4.2e-56 189.9 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ55759.1 - 3e-40 137.9 0.0 4.7e-40 137.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBZ55759.1 - 1.1e-05 24.5 0.0 1.8e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Adeno_terminal PF02459.10 CBZ55759.1 - 0.77 7.8 2.2 3.2 5.7 1.0 2.2 2 0 0 2 2 2 0 Adenoviral DNA terminal protein Vpu PF00558.14 CBZ55759.1 - 6 6.4 2.4 18 5.0 0.4 2.6 2 0 0 2 2 2 0 Vpu protein Seadorna_VP7 PF07387.6 CBZ55759.1 - 10 4.8 0.0 15 4.2 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 SAG PF04092.8 CBZ55760.1 - 2.3e-102 338.0 47.8 1.4e-32 112.6 4.9 4.1 3 1 1 4 4 4 4 SRS domain SAG PF04092.8 CBZ55761.1 - 2.9e-55 185.9 23.4 1.7e-33 115.6 5.0 2.1 2 0 0 2 2 2 2 SRS domain SAG PF04092.8 CBZ55762.1 - 7.1e-57 191.1 18.7 1.6e-33 115.7 4.4 2.2 2 0 0 2 2 2 2 SRS domain DUF788 PF05620.6 CBZ55763.1 - 2.1e-09 37.4 0.2 7e-09 35.7 0.1 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF788) zf-CCCH PF00642.19 CBZ55764.1 - 2.7e-07 30.0 16.5 0.00039 20.0 1.5 3.7 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) PAM2 PF07145.10 CBZ55764.1 - 0.025 14.0 2.7 0.071 12.6 1.9 1.7 1 0 0 1 1 1 0 Ataxin-2 C-terminal region zf-CCHC PF00098.18 CBZ55765.1 - 4.6e-12 45.2 21.0 0.001 18.9 0.5 4.5 4 0 0 4 4 4 4 Zinc knuckle zf-CCHC_4 PF14392.1 CBZ55765.1 - 3.6e-06 26.5 24.8 0.04 13.5 0.8 4.3 4 0 0 4 4 4 4 Zinc knuckle zf-CCHC_2 PF13696.1 CBZ55765.1 - 0.0023 17.3 3.2 0.062 12.8 0.5 4.0 2 1 2 4 4 4 2 Zinc knuckle zf-CCHC_3 PF13917.1 CBZ55765.1 - 0.45 10.2 20.4 3.7 7.3 0.1 4.3 3 1 1 4 4 4 0 Zinc knuckle Siah-Interact_N PF09032.6 CBZ55765.1 - 1.5 8.8 9.4 0.9 9.6 1.6 2.6 2 0 0 2 2 2 0 Siah interacting protein, N terminal ADK_lid PF05191.9 CBZ55765.1 - 8.4 6.1 10.7 0.4 10.3 0.5 2.9 3 0 0 3 3 3 0 Adenylate kinase, active site lid TSP_1 PF00090.14 CBZ55766.1 - 0.00064 19.7 2.3 0.00064 19.7 1.6 6.5 5 0 0 5 5 5 2 Thrombospondin type 1 domain zf-CCCH PF00642.19 CBZ55767.1 - 1.1e-15 56.8 21.3 8.3e-06 25.3 2.1 3.9 4 0 0 4 4 4 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) WD40 PF00400.27 CBZ55768.1 - 1.1e-19 69.4 12.6 1.9e-08 33.8 0.0 6.3 7 0 0 7 7 7 5 WD domain, G-beta repeat Coatomer_WDAD PF04053.9 CBZ55768.1 - 0.0027 16.5 3.7 0.045 12.5 0.3 3.4 4 0 0 4 4 4 1 Coatomer WD associated region TPR_10 PF13374.1 CBZ55768.1 - 0.23 11.4 1.8 12 5.9 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat Porin_3 PF01459.17 CBZ55769.1 - 1e-25 90.5 0.1 1.8e-25 89.8 0.1 1.4 1 1 0 1 1 1 1 Eukaryotic porin DUF4596 PF15363.1 CBZ55769.1 - 0.62 10.0 3.9 1.9 8.4 2.7 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4596) Histone PF00125.19 CBZ55771.1 - 5.9e-34 116.0 0.3 9.4e-34 115.3 0.2 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 CBZ55771.1 - 4.9e-05 23.4 0.0 7.4e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 CBZ55771.1 - 0.014 15.4 0.1 0.03 14.3 0.0 1.5 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.10 CBZ55771.1 - 0.049 13.4 0.2 0.098 12.4 0.0 1.6 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit TAP42 PF04177.7 CBZ55772.1 - 1.9e-46 158.5 0.0 8e-28 97.3 0.0 2.2 2 0 0 2 2 2 2 TAP42-like family SET PF00856.23 CBZ55774.1 - 5.4e-06 26.7 0.4 0.00084 19.6 0.0 2.8 2 1 0 3 3 3 2 SET domain Pkinase PF00069.20 CBZ55775.1 - 1.4e-75 253.8 0.0 1.6e-75 253.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ55775.1 - 3.2e-32 111.6 0.0 4e-32 111.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBZ55775.1 - 0.0013 17.7 0.0 0.0026 16.7 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 CBZ55775.1 - 0.011 14.8 0.0 0.018 14.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CBZ55775.1 - 0.017 14.8 0.0 0.035 13.8 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.17 CBZ55775.1 - 0.023 14.0 0.0 0.057 12.7 0.0 1.4 1 1 0 1 1 1 0 RIO1 family Bac_chlorC PF02043.12 CBZ55776.1 - 0.066 13.0 0.2 0.22 11.3 0.2 1.9 1 0 0 1 1 1 0 Bacteriochlorophyll C binding protein Kinesin PF00225.18 CBZ55778.1 - 3.8e-104 348.0 0.0 3.8e-104 348.0 0.0 1.7 2 0 0 2 2 2 1 Kinesin motor domain KIF1B PF12423.3 CBZ55778.1 - 9.4e-08 31.9 0.9 3.5e-07 30.1 0.1 2.5 2 0 0 2 2 2 1 Kinesin protein 1B OmpH PF03938.9 CBZ55778.1 - 0.0002 21.3 26.1 0.0026 17.6 7.6 2.9 2 0 0 2 2 2 2 Outer membrane protein (OmpH-like) FHA PF00498.21 CBZ55778.1 - 0.0055 16.7 0.0 0.018 15.1 0.0 1.9 1 0 0 1 1 1 1 FHA domain IncA PF04156.9 CBZ55778.1 - 1.5 8.4 24.8 0.4 10.2 1.4 2.6 2 0 0 2 2 2 0 IncA protein DUF342 PF03961.8 CBZ55778.1 - 1.9 6.7 20.6 0.37 9.1 1.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF342) UDPGP PF01704.13 CBZ55779.1 - 5.3e-12 44.9 0.0 7.7e-11 41.1 0.0 2.1 2 0 0 2 2 2 2 UTP--glucose-1-phosphate uridylyltransferase BRE1 PF08647.6 CBZ55780.1 - 0.016 15.1 4.2 0.016 15.1 2.9 7.0 2 2 5 8 8 8 0 BRE1 E3 ubiquitin ligase DUF2746 PF10874.3 CBZ55780.1 - 1.5 9.0 11.8 0.31 11.2 1.7 4.1 4 0 0 4 4 4 0 Protein of unknown function (DUF2746) Reo_sigmaC PF04582.7 CBZ55780.1 - 1.5 7.8 16.7 0.86 8.7 0.5 4.4 3 1 2 5 5 5 0 Reovirus sigma C capsid protein TraG_N PF07916.6 CBZ55780.1 - 5.1 5.4 4.6 9 4.6 3.2 1.3 1 0 0 1 1 1 0 TraG-like protein, N-terminal region Filament PF00038.16 CBZ55780.1 - 5.9 6.2 85.1 0.52 9.7 20.1 4.7 1 1 1 3 3 3 0 Intermediate filament protein NOC3p PF07540.6 CBZ55782.1 - 1.1e-09 38.4 0.0 0.03 14.6 0.0 3.7 1 1 2 3 3 3 3 Nucleolar complex-associated protein HEAT PF02985.17 CBZ55782.1 - 0.25 11.5 4.4 0.5 10.5 0.1 3.6 3 0 0 3 3 3 0 HEAT repeat DUF1265 PF06887.9 CBZ55783.1 - 2 8.1 0.0 3.7 7.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1265) MT-A70 PF05063.9 CBZ55785.1 - 4e-41 140.5 0.5 7.9e-39 133.0 0.4 2.2 1 1 0 1 1 1 1 MT-A70 Cuticle_1 PF08140.6 CBZ55789.1 - 0.036 13.9 0.0 0.26 11.1 0.0 2.3 2 0 0 2 2 2 0 Crustacean cuticle protein repeat Gti1_Pac2 PF09729.4 CBZ55790.1 - 0.28 11.0 3.4 3.9 7.3 0.0 2.6 2 0 0 2 2 2 0 Gti1/Pac2 family FA_desaturase PF00487.19 CBZ55791.1 - 0.03 13.7 0.7 0.053 12.9 0.5 1.3 1 0 0 1 1 1 0 Fatty acid desaturase MgtE PF01769.11 CBZ55791.1 - 0.073 13.3 1.8 10 6.3 0.0 2.4 2 0 0 2 2 2 0 Divalent cation transporter Bd3614_N PF14442.1 CBZ55792.1 - 0.098 12.6 0.1 0.31 11.0 0.0 1.8 2 0 0 2 2 2 0 Bd3614-like deaminase N-terminal Serpin PF00079.15 CBZ55793.1 - 1.9e-66 224.6 0.0 2.3e-66 224.4 0.0 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) XPC-binding PF09280.6 CBZ55793.1 - 0.074 12.5 1.2 0.23 10.9 0.2 2.0 2 0 0 2 2 2 0 XPC-binding domain HCNGP PF07818.8 CBZ55794.1 - 1.5e-19 69.8 0.0 2.5e-19 69.0 0.0 1.3 1 0 0 1 1 1 1 HCNGP-like protein Tbf5 PF06331.7 CBZ55795.1 - 9.6e-20 70.1 0.6 1.7e-19 69.3 0.1 1.6 1 1 1 2 2 2 1 Transcription factor TFIIH complex subunit Tfb5 LXG PF04740.7 CBZ55795.1 - 0.031 14.0 0.2 0.048 13.4 0.1 1.2 1 0 0 1 1 1 0 LXG domain of WXG superfamily DUF3505 PF12013.3 CBZ55795.1 - 0.037 14.2 0.2 0.044 14.0 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3505) tRNA-synt_1c_C PF03950.13 CBZ55796.1 - 5.9e-49 166.0 0.1 1.1e-48 165.1 0.0 1.5 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), anti-codon binding domain tRNA-synt_1c PF00749.16 CBZ55796.1 - 2.4e-30 105.2 0.0 2.4e-30 105.2 0.0 2.4 3 0 0 3 3 3 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c PF00749.16 CBZ55797.1 - 2.8e-57 193.7 0.0 3.8e-57 193.3 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain GST_C_3 PF14497.1 CBZ55797.1 - 0.003 18.0 0.1 0.036 14.5 0.0 2.5 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Striatin PF08232.7 CBZ55800.1 - 0.069 13.4 0.4 0.088 13.1 0.3 1.2 1 0 0 1 1 1 0 Striatin family HMG_box_2 PF09011.5 CBZ55801.1 - 2.9e-22 78.8 1.6 5.6e-22 77.8 1.1 1.5 1 0 0 1 1 1 1 HMG-box domain HMG_box PF00505.14 CBZ55801.1 - 2.6e-11 43.6 2.7 8.1e-11 42.0 1.9 1.9 1 1 0 1 1 1 1 HMG (high mobility group) box CBFD_NFYB_HMF PF00808.18 CBZ55801.1 - 0.002 18.1 0.1 0.014 15.4 0.1 2.3 3 0 0 3 3 3 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Draxin PF15550.1 CBZ55801.1 - 0.011 15.3 1.4 0.011 15.3 1.0 1.4 2 0 0 2 2 2 0 Draxin L31 PF09784.4 CBZ55802.1 - 0.12 12.4 0.1 0.2 11.7 0.1 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L31 DUF3349 PF11829.3 CBZ55804.1 - 0.052 13.9 0.0 0.076 13.4 0.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3349) RRM_1 PF00076.17 CBZ55805.1 - 5.8e-28 96.3 0.0 8.2e-14 50.9 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBZ55805.1 - 3.4e-15 55.7 0.0 9.5e-08 31.9 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBZ55805.1 - 1.3e-09 37.7 0.0 8.9e-09 35.0 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 CBZ55805.1 - 0.15 11.8 0.0 0.31 10.8 0.0 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Hexapep PF00132.19 CBZ55806.1 - 4.8e-12 44.8 7.6 0.00037 19.8 0.3 4.2 3 1 1 4 4 4 4 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 CBZ55806.1 - 0.017 14.6 9.6 0.26 10.8 0.5 4.2 4 1 1 5 5 5 0 Hexapeptide repeat of succinyl-transferase RNA_pol_N PF01194.12 CBZ55808.1 - 6.9e-30 102.8 0.5 8.7e-30 102.5 0.4 1.1 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit Ribosomal_S27e PF01667.12 CBZ55809.1 - 2.1e-26 91.2 8.3 2.6e-26 90.9 5.8 1.1 1 0 0 1 1 1 1 Ribosomal protein S27 IBR PF01485.16 CBZ55809.1 - 0.038 13.8 2.2 0.051 13.4 1.5 1.3 1 1 0 1 1 1 0 IBR domain Zn_Tnp_IS1 PF03811.8 CBZ55809.1 - 0.32 10.5 2.1 1.5 8.3 1.5 2.1 1 1 0 1 1 1 0 InsA N-terminal domain Tnp_zf-ribbon_2 PF13842.1 CBZ55809.1 - 0.78 10.1 4.0 1.9 8.9 2.8 1.8 1 1 0 1 1 1 0 DDE_Tnp_1-like zinc-ribbon RNA_pol_Rpc34 PF05158.7 CBZ55810.1 - 1.5e-38 132.8 2.2 2.3e-30 105.9 0.0 2.9 1 1 1 2 2 2 2 RNA polymerase Rpc34 subunit B-block_TFIIIC PF04182.7 CBZ55810.1 - 0.0041 16.9 0.1 0.0078 16.0 0.0 1.4 1 0 0 1 1 1 1 B-block binding subunit of TFIIIC Ribosomal_L17 PF01196.14 CBZ55811.1 - 3e-26 91.8 0.0 4.6e-26 91.2 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L17 Pkinase PF00069.20 CBZ55812.1 - 9.5e-65 218.3 0.0 6.1e-64 215.6 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ55812.1 - 3.4e-28 98.4 0.0 1e-22 80.4 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase EF-hand_7 PF13499.1 CBZ55812.1 - 4.2e-12 46.0 0.1 4.7e-06 26.6 0.0 2.7 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 CBZ55812.1 - 6.3e-12 44.3 0.4 0.00017 21.1 0.0 2.8 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.27 CBZ55812.1 - 3e-10 38.6 2.4 0.00036 19.6 0.1 2.7 2 0 0 2 2 2 2 EF hand EF-hand_5 PF13202.1 CBZ55812.1 - 3.6e-09 35.5 2.1 0.0001 21.4 0.1 2.5 2 0 0 2 2 2 2 EF hand APH PF01636.18 CBZ55812.1 - 0.00027 20.7 0.1 0.00081 19.1 0.0 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 CBZ55812.1 - 0.0015 17.6 0.0 0.0031 16.6 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 CBZ55812.1 - 0.0081 15.7 0.1 0.62 9.6 0.0 2.3 2 0 0 2 2 2 1 Choline/ethanolamine kinase EF-hand_8 PF13833.1 CBZ55812.1 - 0.03 13.9 0.8 4.1 7.0 0.0 2.6 2 0 0 2 2 2 0 EF-hand domain pair eIF-1a PF01176.14 CBZ55814.1 - 8.4e-07 28.3 0.0 1.5e-05 24.3 0.0 2.2 2 0 0 2 2 2 1 Translation initiation factor 1A / IF-1 RPAP3_C PF13877.1 CBZ55815.1 - 0.0028 17.5 0.5 1.5 8.8 0.0 3.5 3 0 0 3 3 3 2 Potential Monad-binding region of RPAP3 TPR_16 PF13432.1 CBZ55815.1 - 0.46 11.2 4.9 0.28 11.9 0.2 3.0 4 0 0 4 4 4 0 Tetratricopeptide repeat FliC PF12445.3 CBZ55816.1 - 0.12 12.4 0.0 0.14 12.2 0.0 1.2 1 0 0 1 1 1 0 Flagellin protein CD52 PF15116.1 CBZ55816.1 - 1.7 8.5 4.4 0.28 11.0 0.3 1.7 2 0 0 2 2 2 0 CAMPATH-1 antigen GAS PF13851.1 CBZ55817.1 - 1e-46 158.7 34.1 1e-46 158.7 23.6 3.5 2 2 1 3 3 3 2 Growth-arrest specific micro-tubule binding FtsA PF14450.1 CBZ55817.1 - 0.48 10.2 1.7 3 7.6 1.2 2.4 1 1 0 1 1 1 0 Cell division protein FtsA Scm3 PF10384.4 CBZ55817.1 - 3.2 7.3 8.0 0.19 11.2 0.4 2.9 3 0 0 3 3 3 0 Centromere protein Scm3 Tctex-1 PF03645.8 CBZ55818.1 - 6.7e-23 80.4 0.0 8e-23 80.2 0.0 1.1 1 0 0 1 1 1 1 Tctex-1 family FerA PF08165.6 CBZ55818.1 - 0.0065 16.1 0.1 0.0091 15.6 0.1 1.3 1 0 0 1 1 1 1 FerA (NUC095) domain Ribosomal_S6 PF01250.12 CBZ55819.1 - 2e-13 49.9 0.0 3.2e-13 49.3 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S6 Cornifin PF02389.10 CBZ55820.1 - 4.7e-14 52.6 34.4 1.1e-11 44.8 10.4 3.4 1 1 2 3 3 3 3 Cornifin (SPRR) family Exostosin PF03016.10 CBZ55821.1 - 4.6e-09 35.7 0.3 4.6e-09 35.7 0.2 1.9 2 0 0 2 2 2 1 Exostosin family CCER1 PF15482.1 CBZ55822.1 - 3.5 7.2 13.9 1.2 8.6 6.7 2.1 2 0 0 2 2 2 0 Coiled-coil domain-containing glutamate-rich protein family 1 AP2 PF00847.15 CBZ55823.1 - 6.8e-07 29.3 1.9 1.6e-06 28.1 1.3 1.6 1 0 0 1 1 1 1 AP2 domain DnaJ PF00226.26 CBZ55824.1 - 2.7e-20 71.8 1.4 4.5e-20 71.1 1.0 1.4 1 0 0 1 1 1 1 DnaJ domain Thioredoxin PF00085.15 CBZ55824.1 - 6.4e-11 41.8 0.0 2.5e-05 23.8 0.0 2.3 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_2 PF13098.1 CBZ55824.1 - 0.0012 18.9 0.1 0.53 10.4 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin-like domain DUF836 PF05768.9 CBZ55824.1 - 0.0014 18.8 0.9 0.27 11.5 0.0 2.5 2 0 0 2 2 2 2 Glutaredoxin-like domain (DUF836) Thioredoxin_8 PF13905.1 CBZ55824.1 - 0.0035 17.4 0.1 3.1 7.9 0.0 2.7 3 0 0 3 3 3 2 Thioredoxin-like Thioredoxin_4 PF13462.1 CBZ55824.1 - 0.1 12.6 0.3 9 6.2 0.1 2.3 2 0 0 2 2 2 0 Thioredoxin Arteri_nucleo PF01481.11 CBZ55825.1 - 0.033 14.2 0.5 0.065 13.3 0.4 1.4 1 0 0 1 1 1 0 Arterivirus nucleocapsid protein M16C_assoc PF08367.6 CBZ55825.1 - 0.22 10.3 3.3 0.29 9.9 2.3 1.1 1 0 0 1 1 1 0 Peptidase M16C associated GvpL_GvpF PF06386.6 CBZ55825.1 - 4.3 6.8 9.6 3.8 7.0 5.8 1.4 1 1 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF DUF2681 PF10883.3 CBZ55825.1 - 7.8 6.7 7.3 17 5.6 5.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2681) adh_short PF00106.20 CBZ55826.1 - 1.3e-44 152.0 0.9 2.1e-44 151.4 0.6 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CBZ55826.1 - 1.1e-28 100.6 0.2 1.5e-28 100.2 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CBZ55826.1 - 8.8e-24 84.1 0.2 1.5e-23 83.4 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 CBZ55826.1 - 0.00035 20.0 0.4 0.00074 19.0 0.3 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Seadorna_Vp10 PF07322.6 CBZ55826.1 - 0.015 14.5 0.0 0.024 13.8 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus Vp10 Eno-Rase_NADH_b PF12242.3 CBZ55826.1 - 0.02 14.6 0.7 0.042 13.6 0.5 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Glycos_transf_N PF04413.11 CBZ55826.1 - 0.031 13.4 0.0 0.058 12.5 0.0 1.4 1 0 0 1 1 1 0 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) Bac_chlorC PF02043.12 CBZ55826.1 - 0.097 12.4 0.6 0.57 10.0 0.1 2.3 2 0 0 2 2 2 0 Bacteriochlorophyll C binding protein HHH_5 PF14520.1 CBZ55826.1 - 0.11 12.7 0.0 0.25 11.5 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix domain DUF1776 PF08643.5 CBZ55826.1 - 0.11 11.6 0.0 0.16 11.0 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) MMR_HSR1 PF01926.18 CBZ55827.1 - 7.8e-11 41.9 0.0 1.3e-10 41.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 CBZ55827.1 - 0.00065 19.1 0.0 0.38 10.1 0.0 2.3 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain DUF258 PF03193.11 CBZ55827.1 - 0.00088 18.4 0.0 0.0016 17.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Dynamin_N PF00350.18 CBZ55827.1 - 0.0009 19.1 0.0 0.024 14.4 0.0 2.2 2 0 0 2 2 2 1 Dynamin family FeoB_N PF02421.13 CBZ55827.1 - 0.016 14.4 0.0 0.11 11.7 0.0 2.1 2 0 0 2 2 2 0 Ferrous iron transport protein B Miro PF08477.8 CBZ55827.1 - 0.086 13.3 0.0 0.17 12.3 0.0 1.7 1 1 0 1 1 1 0 Miro-like protein Sec20 PF03908.8 CBZ55829.1 - 1.9e-14 53.1 0.3 1.9e-14 53.1 0.2 1.7 2 0 0 2 2 2 1 Sec20 DUF1212 PF06738.7 CBZ55829.1 - 0.1 12.0 0.2 0.16 11.4 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1212) DUF2450 PF10475.4 CBZ55829.1 - 0.15 10.9 0.9 0.29 10.0 0.7 1.4 1 0 0 1 1 1 0 Protein of unknown function N-terminal domain (DUF2450) DUF4131 PF13567.1 CBZ55829.1 - 0.37 10.1 2.8 0.7 9.2 1.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) PrgI PF12666.2 CBZ55829.1 - 0.44 10.7 5.0 0.81 9.8 3.5 1.3 1 0 0 1 1 1 0 PrgI family protein S1 PF00575.18 CBZ55830.1 - 1.6e-14 53.7 0.5 1.3e-06 28.4 0.0 4.2 4 0 0 4 4 4 3 S1 RNA binding domain PCI PF01399.22 CBZ55831.1 - 1.9e-11 44.2 0.0 1.1e-10 41.7 0.0 2.3 2 0 0 2 2 2 1 PCI domain S6PP PF05116.8 CBZ55833.1 - 1.1e-38 132.9 0.0 5.5e-17 61.8 0.0 4.0 3 1 1 4 4 4 3 Sucrose-6F-phosphate phosphohydrolase Hydrolase_3 PF08282.7 CBZ55833.1 - 6.3e-15 55.4 0.0 1.3e-09 37.9 0.0 2.1 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.2 CBZ55833.1 - 0.01 15.9 0.6 1.7 8.7 0.4 2.4 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 CBZ55833.1 - 0.016 15.5 0.0 0.49 10.7 0.0 2.2 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase zf-DHHC PF01529.15 CBZ55835.1 - 4.4e-37 127.1 2.7 4.4e-37 127.1 1.9 2.0 2 0 0 2 2 2 1 DHHC palmitoyltransferase KH_1 PF00013.24 CBZ55836.1 - 7.6e-39 131.1 2.2 3e-14 52.4 0.1 3.2 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 CBZ55836.1 - 6.3e-28 95.9 6.2 8.4e-09 34.8 0.8 3.5 3 0 0 3 3 3 3 KH domain KH_2 PF07650.12 CBZ55836.1 - 1.5e-06 27.7 3.2 0.088 12.3 0.0 3.2 3 0 0 3 3 3 3 KH domain KH_5 PF13184.1 CBZ55836.1 - 6.4e-06 25.8 0.6 0.54 10.1 0.0 3.3 3 0 0 3 3 3 2 NusA-like KH domain KH_4 PF13083.1 CBZ55836.1 - 5.5e-05 22.7 0.3 5 6.8 0.0 3.3 3 0 0 3 3 3 3 KH domain PNPase_C PF12111.3 CBZ55836.1 - 3.7 6.8 10.5 8.6 5.6 3.0 2.8 2 0 0 2 2 2 0 Polyribonucleotide phosphorylase C terminal AhpC-TSA PF00578.16 CBZ55837.1 - 4.7e-36 123.2 0.0 6.2e-36 122.8 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 CBZ55837.1 - 2.6e-17 62.7 0.0 3.3e-17 62.3 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.4 CBZ55837.1 - 9.5e-15 53.9 0.0 2.8e-14 52.4 0.0 1.8 2 0 0 2 2 2 1 C-terminal domain of 1-Cys peroxiredoxin DNA_pol_B PF00136.16 CBZ55839.1 - 1.2e-124 416.6 0.0 1.8e-124 416.1 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_alpha_N PF12254.3 CBZ55839.1 - 1.7e-15 56.5 7.2 4.7e-15 55.1 5.0 1.8 1 0 0 1 1 1 1 DNA polymerase alpha subunit p180 N terminal DNA_pol_B_exo1 PF03104.14 CBZ55839.1 - 2.7e-13 49.5 0.0 1.1e-12 47.5 0.0 1.9 2 1 0 2 2 2 1 DNA polymerase family B, exonuclease domain zf-DNA_Pol PF08996.5 CBZ55839.1 - 0.0029 16.9 2.6 0.021 14.1 0.6 2.6 2 0 0 2 2 2 1 DNA Polymerase alpha zinc finger MYCBPAP PF14646.1 CBZ55840.1 - 0.00064 18.5 0.0 0.0018 17.0 0.0 1.7 1 0 0 1 1 1 1 MYCBP-associated protein family PapD-like PF14874.1 CBZ55840.1 - 0.0072 16.2 0.0 5.5 6.9 0.0 4.0 4 0 0 4 4 4 1 Flagellar-associated PapD-like PHD PF00628.24 CBZ55844.1 - 6.6e-06 25.7 4.2 1.7e-05 24.4 2.9 1.7 1 0 0 1 1 1 1 PHD-finger Ribosomal_S8e PF01201.17 CBZ55846.1 - 2.4e-51 173.3 0.2 2.9e-51 173.0 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S8e WD40 PF00400.27 CBZ55847.1 - 2.1e-21 74.9 8.0 8.9e-06 25.3 0.0 6.1 6 0 0 6 6 6 4 WD domain, G-beta repeat EPTP PF03736.12 CBZ55847.1 - 0.0075 15.9 0.0 0.02 14.6 0.0 1.7 1 0 0 1 1 1 1 EPTP domain EGF PF00008.22 CBZ55849.1 - 1.3e-10 40.9 63.5 0.0054 16.6 6.5 6.6 6 1 0 6 6 6 5 EGF-like domain EGF_3 PF12947.2 CBZ55849.1 - 9.5e-09 35.0 60.9 0.0004 20.2 9.6 6.3 6 0 0 6 6 6 5 EGF domain FXa_inhibition PF14670.1 CBZ55849.1 - 2.4e-07 30.7 70.1 0.0071 16.4 2.5 6.6 5 1 1 6 6 6 5 Coagulation Factor Xa inhibitory site cEGF PF12662.2 CBZ55849.1 - 0.013 15.0 51.0 0.075 12.6 0.9 6.9 7 0 0 7 7 7 0 Complement Clr-like EGF-like DUF1049 PF06305.6 CBZ55849.1 - 0.028 13.9 0.1 0.13 11.7 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) EGF_CA PF07645.10 CBZ55849.1 - 0.11 12.5 58.9 2 8.4 6.3 5.9 1 1 4 5 5 5 0 Calcium-binding EGF domain CD34_antigen PF06365.7 CBZ55849.1 - 0.16 11.5 0.0 0.43 10.1 0.0 1.6 2 0 0 2 2 2 0 CD34/Podocalyxin family EGF_MSP1_1 PF12946.2 CBZ55849.1 - 3.3 7.5 36.6 0.38 10.5 1.7 5.1 4 0 0 4 4 4 0 MSP1 EGF domain 1 EGF PF00008.22 CBZ55850.1 - 4.2e-06 26.6 52.3 6.7e-05 22.7 3.0 5.8 5 1 0 5 5 5 4 EGF-like domain FXa_inhibition PF14670.1 CBZ55850.1 - 0.0015 18.6 55.7 0.054 13.6 4.1 4.6 4 0 0 4 4 4 3 Coagulation Factor Xa inhibitory site cEGF PF12662.2 CBZ55850.1 - 0.021 14.4 29.5 0.07 12.7 1.6 4.7 4 0 0 4 4 4 0 Complement Clr-like EGF-like EGF_3 PF12947.2 CBZ55850.1 - 2.1 8.3 52.2 1.1 9.2 4.8 5.7 4 2 0 4 4 4 0 EGF domain cEGF PF12662.2 CBZ55851.1 - 4.9e-07 29.2 98.6 0.011 15.3 0.3 12.1 13 0 0 13 13 13 9 Complement Clr-like EGF-like FXa_inhibition PF14670.1 CBZ55851.1 - 5.1e-07 29.7 130.0 0.04 14.0 5.9 11.6 8 3 2 10 10 10 8 Coagulation Factor Xa inhibitory site EGF_3 PF12947.2 CBZ55851.1 - 0.00022 21.1 10.4 0.00022 21.1 7.2 11.9 9 3 2 11 11 11 7 EGF domain EGF PF00008.22 CBZ55851.1 - 0.0044 16.9 9.6 0.0044 16.9 6.6 13.1 12 4 1 13 13 13 8 EGF-like domain EGF_MSP1_1 PF12946.2 CBZ55851.1 - 0.009 15.7 6.0 0.009 15.7 4.2 10.0 9 1 0 9 9 9 3 MSP1 EGF domain 1 Peptidase_S9 PF00326.16 CBZ55852.1 - 1.5e-28 99.5 0.2 2.4e-21 75.9 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family DPPIV_N PF00930.16 CBZ55852.1 - 1.7e-23 82.8 0.0 3e-12 45.8 0.0 4.3 4 0 0 4 4 4 3 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S28 PF05577.7 CBZ55852.1 - 0.47 8.9 0.5 0.76 8.2 0.3 1.2 1 0 0 1 1 1 0 Serine carboxypeptidase S28 E1-E2_ATPase PF00122.15 CBZ55853.1 - 4.6e-13 48.7 4.0 1.5e-06 27.4 0.0 3.3 3 0 0 3 3 3 2 E1-E2 ATPase Hydrolase PF00702.21 CBZ55853.1 - 1.3e-11 45.3 0.3 1.3e-05 25.6 0.1 3.5 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase HAD PF12710.2 CBZ55853.1 - 1.6e-09 38.2 0.1 0.0033 17.6 0.0 3.6 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 CBZ55853.1 - 4.7e-05 23.2 0.1 0.00033 20.5 0.0 2.4 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit DUF4392 PF14336.1 CBZ55853.1 - 0.018 13.8 0.8 1.3 7.8 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4392) Hydrolase_3 PF08282.7 CBZ55853.1 - 0.28 10.7 0.7 2.4 7.6 0.1 2.1 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Rpp20 PF12328.3 CBZ55854.1 - 0.00069 19.2 0.0 0.0035 17.0 0.0 2.0 2 0 0 2 2 2 1 Rpp20 subunit of nuclear RNase MRP and P Alba PF01918.16 CBZ55854.1 - 0.027 14.0 0.0 0.098 12.2 0.0 1.9 1 1 0 1 1 1 0 Alba DUF4200 PF13863.1 CBZ55855.1 - 0.21 11.5 2.6 0.49 10.3 1.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) EI24 PF07264.6 CBZ55856.1 - 1.8 7.9 12.9 3.9 6.8 9.1 1.4 1 1 0 1 1 1 0 Etoposide-induced protein 2.4 (EI24) ORC2 PF04084.9 CBZ55858.1 - 3.7e-32 111.4 0.0 1.3e-31 109.6 0.0 1.7 1 1 0 1 1 1 1 Origin recognition complex subunit 2 Pkinase PF00069.20 CBZ55859.1 - 0.003 16.7 0.0 0.0057 15.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain RXT2_N PF08595.6 CBZ55859.1 - 6.5 6.5 6.6 14 5.4 4.6 1.6 1 0 0 1 1 1 0 RXT2-like, N-terminal Rhomboid PF01694.17 CBZ55860.1 - 2.8e-13 50.1 7.2 2.8e-13 50.1 5.0 1.9 2 0 0 2 2 2 1 Rhomboid family Atracotoxin PF05353.6 CBZ55860.1 - 0.13 12.1 0.4 0.26 11.1 0.3 1.5 1 0 0 1 1 1 0 Delta Atracotoxin Herpes_capsid PF06112.6 CBZ55860.1 - 1.1 9.2 4.6 1.6 8.7 3.2 1.3 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Ribosomal_S27 PF01599.14 CBZ55863.1 - 1.9e-25 88.4 3.1 3.1e-25 87.7 2.2 1.4 1 0 0 1 1 1 1 Ribosomal protein S27a ubiquitin PF00240.18 CBZ55863.1 - 4.5e-16 58.0 0.2 1.2e-15 56.6 0.0 1.7 2 0 0 2 2 2 1 Ubiquitin family Rad60-SLD PF11976.3 CBZ55863.1 - 1e-09 37.9 0.2 2.4e-09 36.7 0.0 1.7 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 CBZ55863.1 - 0.002 18.3 0.0 0.0084 16.3 0.0 2.0 1 1 0 1 1 1 1 Ubiquitin-like domain IBR PF01485.16 CBZ55863.1 - 0.011 15.6 1.0 0.018 14.9 0.7 1.4 1 0 0 1 1 1 0 IBR domain Telomere_Sde2 PF13019.1 CBZ55863.1 - 0.024 14.3 1.6 0.03 14.0 0.0 1.8 1 1 1 2 2 2 0 Telomere stability and silencing Cucumo_2B PF03263.8 CBZ55863.1 - 0.034 14.4 0.0 0.052 13.8 0.0 1.3 1 0 0 1 1 1 0 Cucumovirus protein 2B BIR PF00653.16 CBZ55863.1 - 0.85 10.0 3.7 53 4.3 2.6 2.2 1 1 0 1 1 1 0 Inhibitor of Apoptosis domain ASFV_L11L PF05293.6 CBZ55864.1 - 0.21 11.7 3.7 0.39 10.8 2.6 1.5 1 1 0 1 1 1 0 African swine fever virus (ASFV) L11L protein zf-RING_2 PF13639.1 CBZ55867.1 - 8.5e-05 22.2 2.8 0.00023 20.9 1.9 1.8 1 0 0 1 1 1 1 Ring finger domain zf-CCHC_2 PF13696.1 CBZ55867.1 - 0.00024 20.5 2.0 0.00055 19.3 1.4 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-C3HC4_2 PF13923.1 CBZ55867.1 - 0.00028 20.8 3.9 0.00082 19.3 2.7 1.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 CBZ55867.1 - 0.0056 16.5 3.7 0.019 14.8 2.6 1.9 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING TerY-C PF15616.1 CBZ55867.1 - 0.084 12.8 3.1 0.89 9.4 0.1 2.7 2 0 0 2 2 2 0 TerY-C metal binding domain zf-CCHC PF00098.18 CBZ55867.1 - 9.2 6.3 11.4 1.5 8.9 3.3 2.7 2 0 0 2 2 2 0 Zinc knuckle E1_dh PF00676.15 CBZ55868.1 - 3.5e-92 308.3 0.1 4.5e-92 307.9 0.0 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.16 CBZ55868.1 - 3.8e-09 36.2 1.1 2.5e-08 33.6 0.7 2.1 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Transketolase_N PF00456.16 CBZ55868.1 - 3.1e-06 26.2 0.0 4.7e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain DXP_synthase_N PF13292.1 CBZ55868.1 - 0.00014 20.9 0.0 0.00022 20.2 0.0 1.3 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase Ribosomal_L21e PF01157.13 CBZ55869.1 - 8e-37 125.0 3.3 1.1e-36 124.5 2.3 1.2 1 0 0 1 1 1 1 Ribosomal protein L21e DUF1103 PF06513.6 CBZ55869.1 - 0.055 12.8 1.9 0.072 12.4 1.3 1.1 1 0 0 1 1 1 0 Repeat of unknown function (DUF1103) ARGLU PF15346.1 CBZ55869.1 - 0.11 12.2 3.8 0.17 11.6 2.6 1.2 1 0 0 1 1 1 0 Arginine and glutamate-rich 1 MORN PF02493.15 CBZ55870.1 - 7.6e-62 201.5 78.7 3.6e-09 35.8 1.3 10.3 10 0 0 10 10 10 9 MORN repeat SNF2_N PF00176.18 CBZ55871.1 - 7.5e-31 107.0 0.0 6.8e-19 67.7 0.0 2.9 3 0 0 3 3 3 2 SNF2 family N-terminal domain Helicase_C PF00271.26 CBZ55871.1 - 9.8e-10 38.1 0.0 2.1e-09 37.1 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain FHIPEP PF00771.15 CBZ55871.1 - 10 4.3 0.1 25 3.0 0.0 1.5 2 0 0 2 2 2 0 FHIPEP family PIP5K PF01504.13 CBZ55872.1 - 9.5e-49 165.7 0.0 9.5e-19 67.4 0.0 3.1 3 0 0 3 3 3 3 Phosphatidylinositol-4-phosphate 5-Kinase Peptidase_C23 PF05379.6 CBZ55873.1 - 0.092 12.7 0.1 0.26 11.2 0.1 1.7 1 0 0 1 1 1 0 Carlavirus endopeptidase WD40 PF00400.27 CBZ55874.1 - 4.1e-09 35.9 11.4 0.051 13.4 0.0 6.0 5 0 0 5 5 5 5 WD domain, G-beta repeat Img2 PF05046.9 CBZ55876.1 - 2.4e-18 66.1 0.0 3.6e-18 65.5 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial large subunit ribosomal protein (Img2) SspB PF04386.8 CBZ55876.1 - 0.00039 20.0 0.0 0.0005 19.7 0.0 1.1 1 0 0 1 1 1 1 Stringent starvation protein B Hjc PF01870.13 CBZ55876.1 - 0.055 13.0 0.0 0.13 11.9 0.0 1.7 1 1 0 1 1 1 0 Archaeal holliday junction resolvase (hjc) Abhydrolase_5 PF12695.2 CBZ55877.1 - 6.2e-06 26.0 2.5 7.9e-05 22.4 1.8 2.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 CBZ55877.1 - 0.0017 17.6 0.0 0.18 11.0 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Ctr PF04145.10 CBZ55877.1 - 0.17 11.9 2.0 4.6 7.2 0.3 2.9 2 1 0 2 2 2 0 Ctr copper transporter family SprT-like PF10263.4 CBZ55878.1 - 4.4e-41 140.1 1.1 6.7e-41 139.5 0.8 1.3 1 0 0 1 1 1 1 SprT-like family WLM PF08325.5 CBZ55878.1 - 0.035 13.9 0.2 0.081 12.7 0.1 1.7 1 0 0 1 1 1 0 WLM domain zf-C2H2 PF00096.21 CBZ55878.1 - 0.074 13.4 0.2 0.074 13.4 0.2 2.5 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2HC_2 PF13913.1 CBZ55878.1 - 0.54 9.9 5.4 1.5 8.5 3.8 1.8 1 0 0 1 1 1 0 zinc-finger of a C2HC-type Myf5 PF12232.3 CBZ55879.1 - 2.2 8.9 9.1 0.087 13.4 1.1 2.6 3 0 0 3 3 3 0 Myogenic determination factor 5 MIF4G PF02854.14 CBZ55880.1 - 1.6e-33 115.9 3.3 2.3e-17 63.0 0.1 4.4 4 0 0 4 4 4 4 MIF4G domain Upf2 PF04050.9 CBZ55880.1 - 6.1e-08 32.6 17.6 3.4e-07 30.1 12.2 2.4 1 1 0 1 1 1 1 Up-frameshift suppressor 2 DNA_pol_viral_N PF00242.12 CBZ55880.1 - 1.4 7.8 17.7 5.2 5.9 12.3 1.9 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain Neur_chan_memb PF02932.11 CBZ55880.1 - 6.3 6.6 11.5 5.1 6.9 0.9 3.9 3 2 0 3 3 3 0 Neurotransmitter-gated ion-channel transmembrane region RNA_pol PF00940.14 CBZ55882.1 - 7.9e-129 429.6 0.0 2.1e-105 352.5 0.0 2.2 2 0 0 2 2 2 2 DNA-dependent RNA polymerase RPOL_N PF14700.1 CBZ55882.1 - 6.9e-17 61.6 7.4 3.9e-08 32.9 0.1 4.5 4 0 0 4 4 4 4 DNA-directed RNA polymerase N-terminal SAG PF04092.8 CBZ55883.1 - 3.3e-10 40.4 0.1 1e-05 25.8 0.2 2.4 2 1 0 2 2 2 2 SRS domain DUF1731 PF08338.6 CBZ55884.1 - 1.7e-14 53.0 0.3 3.8e-14 51.8 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF1731) Epimerase PF01370.16 CBZ55884.1 - 3.8e-05 23.2 0.0 0.018 14.5 0.0 3.6 3 1 0 4 4 4 1 NAD dependent epimerase/dehydratase family Phosducin PF02114.11 CBZ55886.1 - 9.9e-12 44.1 1.0 1.8e-07 30.1 0.0 2.2 1 1 1 2 2 2 2 Phosducin TraF PF13728.1 CBZ55886.1 - 0.0025 17.3 0.0 0.0036 16.8 0.0 1.2 1 0 0 1 1 1 1 F plasmid transfer operon protein DUF1977 PF09320.6 CBZ55886.1 - 0.0036 17.5 0.8 0.0063 16.7 0.5 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1977) Thioredoxin PF00085.15 CBZ55886.1 - 0.021 14.5 0.0 0.042 13.5 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin HAD_2 PF13419.1 CBZ55887.1 - 0.1 12.8 0.1 9.9 6.3 0.0 2.4 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase TPR_14 PF13428.1 CBZ55888.1 - 0.00066 20.0 1.5 0.0064 17.0 1.4 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.12 CBZ55888.1 - 0.0015 18.3 0.1 0.0028 17.4 0.1 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_11 PF13414.1 CBZ55888.1 - 0.019 14.5 0.1 0.034 13.8 0.1 1.4 1 0 0 1 1 1 0 TPR repeat TPR_19 PF14559.1 CBZ55888.1 - 0.028 14.7 0.1 0.1 12.9 0.1 1.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.1 CBZ55888.1 - 0.065 13.7 0.1 0.2 12.1 0.0 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_4 PF07721.9 CBZ55888.1 - 0.29 11.6 6.9 0.52 10.8 4.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.1 CBZ55888.1 - 0.51 11.0 4.3 0.38 11.4 1.2 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat Serpin PF00079.15 CBZ55889.1 - 3.6e-72 243.5 0.1 4.3e-72 243.2 0.1 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) 2OG-FeII_Oxy_2 PF13532.1 CBZ55890.1 - 0.029 14.2 0.1 0.15 11.8 0.1 2.1 3 0 0 3 3 3 0 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 CBZ55890.1 - 0.074 13.3 0.1 1 9.6 0.0 2.3 2 0 0 2 2 2 0 2OG-Fe(II) oxygenase superfamily Thioredoxin_7 PF13899.1 CBZ55890.1 - 0.11 12.5 0.0 0.21 11.6 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin-like zf-RING_2 PF13639.1 CBZ55891.1 - 9.8e-12 44.5 6.4 9.8e-12 44.5 4.5 3.4 4 0 0 4 4 4 1 Ring finger domain zf-rbx1 PF12678.2 CBZ55891.1 - 1.6e-05 24.8 3.6 1.6e-05 24.8 2.5 2.8 3 0 0 3 3 3 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 CBZ55891.1 - 3.2e-05 23.8 4.4 3.2e-05 23.8 3.1 2.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CBZ55891.1 - 0.00021 20.8 3.4 0.00021 20.8 2.4 2.8 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CBZ55891.1 - 0.0015 18.1 1.8 0.0015 18.1 1.2 3.7 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.3 CBZ55891.1 - 1.4 8.9 13.5 0.16 11.9 4.2 2.9 2 1 0 2 2 2 0 FANCL C-terminal domain zf-Apc11 PF12861.2 CBZ55891.1 - 1.4 8.8 10.5 0.04 13.7 1.2 2.9 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 11 RING-H2 finger ARID PF01388.16 CBZ55892.1 - 2.6e-11 43.1 0.1 4.9e-11 42.3 0.1 1.5 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain TauE PF01925.14 CBZ55893.1 - 6.8e-21 74.8 18.8 1.2e-10 41.2 8.1 2.2 2 0 0 2 2 2 2 Sulfite exporter TauE/SafE IncA PF04156.9 CBZ55894.1 - 0.0012 18.5 5.1 0.0012 18.5 3.5 5.5 4 1 1 5 5 5 1 IncA protein zf-CCCH PF00642.19 CBZ55895.1 - 3.6e-08 32.9 28.4 0.00011 21.7 1.8 4.2 4 1 0 4 4 4 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 CBZ55895.1 - 2.7 8.1 13.4 2.3 8.3 0.7 4.1 3 0 0 3 3 3 0 Zinc finger C-x8-C-x5-C-x3-H type zf-LITAF-like PF10601.4 CBZ55896.1 - 2e-15 56.3 6.8 2e-15 56.3 4.7 2.2 2 0 0 2 2 2 1 LITAF-like zinc ribbon domain DiS_P_DiS PF06750.8 CBZ55896.1 - 0.33 10.7 4.6 0.59 9.9 0.4 2.3 2 0 0 2 2 2 0 Bacterial Peptidase A24 N-terminal domain Zn-ribbon_8 PF09723.5 CBZ55896.1 - 0.77 9.7 3.0 6.1 6.8 0.1 2.7 3 0 0 3 3 3 0 Zinc ribbon domain zinc_ribbon_4 PF13717.1 CBZ55896.1 - 4.5 7.0 9.6 6.1 6.6 1.7 2.9 2 1 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_5 PF13719.1 CBZ55896.1 - 4.7 6.8 9.9 6.8 6.3 1.8 2.9 2 1 0 2 2 2 0 zinc-ribbon domain CRAL_TRIO PF00650.15 CBZ55897.1 - 6.1e-33 113.5 0.0 9.8e-33 112.8 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.1 CBZ55897.1 - 1.3e-13 51.1 0.0 1.8e-13 50.6 0.0 1.2 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO_N PF03765.10 CBZ55897.1 - 3.1e-05 24.0 0.0 7.8e-05 22.7 0.0 1.7 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain DnaJ-X PF14308.1 CBZ55898.1 - 4.8e-54 182.7 17.1 1.1e-51 175.0 11.8 2.4 1 1 0 1 1 1 1 X-domain of DnaJ-containing DnaJ PF00226.26 CBZ55898.1 - 2.7e-24 84.6 3.1 6.5e-24 83.4 2.1 1.7 1 0 0 1 1 1 1 DnaJ domain ATG_C PF09333.6 CBZ55898.1 - 2e-07 31.0 1.0 5.7e-07 29.6 0.0 2.3 2 0 0 2 2 2 1 ATG C terminal domain CLASP_N PF12348.3 CBZ55898.1 - 0.02 14.2 0.0 0.038 13.3 0.0 1.4 1 0 0 1 1 1 0 CLASP N terminal COG2 PF06148.6 CBZ55898.1 - 0.077 12.8 1.9 3.5 7.5 0.4 2.4 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Tetraspannin PF00335.15 CBZ55899.1 - 6.5 5.9 13.3 5.2 6.2 7.0 2.2 1 1 0 1 1 1 0 Tetraspanin family PAP2_C PF14360.1 CBZ55902.1 - 3e-09 37.0 4.2 1e-07 32.0 0.2 3.4 4 0 0 4 4 4 2 PAP2 superfamily C-terminal DUF4577 PF15145.1 CBZ55902.1 - 0.01 15.7 0.1 0.039 13.8 0.1 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4577) HAMP PF00672.20 CBZ55902.1 - 0.047 13.8 1.4 0.071 13.2 0.0 2.0 2 0 0 2 2 2 0 HAMP domain PRP21_like_P PF12230.3 CBZ55903.1 - 1.2e-46 159.0 27.5 1.1e-27 97.1 6.0 2.7 2 1 1 3 3 3 2 Pre-mRNA splicing factor PRP21 like protein Surp PF01805.15 CBZ55903.1 - 3.2e-38 129.1 4.4 1.4e-19 69.4 0.8 2.5 2 0 0 2 2 2 2 Surp module DUF1682 PF07946.9 CBZ55903.1 - 0.0027 16.6 1.0 0.0027 16.6 0.7 3.0 3 0 0 3 3 3 1 Protein of unknown function (DUF1682) B56 PF01603.15 CBZ55904.1 - 8.5e-157 521.9 12.1 1e-156 521.6 8.4 1.1 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Peptidase_S49_N PF08496.5 CBZ55904.1 - 0.091 12.5 0.3 0.17 11.6 0.2 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal BSD PF03909.12 CBZ55905.1 - 0.00018 21.1 0.9 0.028 14.1 0.0 3.1 3 0 0 3 3 3 2 BSD domain PLDc_2 PF13091.1 CBZ55906.1 - 3.8e-07 29.8 0.0 0.0099 15.6 0.0 3.3 3 0 0 3 3 3 2 PLD-like domain PLDc PF00614.17 CBZ55906.1 - 0.0007 19.3 0.5 0.0014 18.3 0.0 1.9 2 0 0 2 2 2 1 Phospholipase D Active site motif Cytochrom_C1 PF02167.10 CBZ55907.1 - 7.1e-79 264.4 0.0 9e-79 264.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.1 CBZ55907.1 - 0.0011 19.0 0.0 0.0022 18.0 0.0 1.6 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.16 CBZ55907.1 - 0.0071 17.1 0.0 0.016 16.0 0.0 1.7 1 0 0 1 1 1 1 Cytochrome c Asp PF00026.18 CBZ55908.1 - 8.4e-66 222.3 0.0 1e-65 222.0 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 CBZ55908.1 - 0.0001 22.2 1.6 0.00018 21.5 0.0 2.3 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal DuffyBP_N PF12377.3 CBZ55908.1 - 0.044 13.9 0.1 0.31 11.2 0.0 2.2 2 0 0 2 2 2 0 Duffy binding protein N terminal V-ATPase_G PF03179.10 CBZ55909.1 - 2.1e-27 95.4 8.4 2.4e-27 95.2 5.8 1.0 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit ADPrib_exo_Tox PF03496.9 CBZ55909.1 - 0.0039 16.4 0.9 0.0049 16.0 0.6 1.1 1 0 0 1 1 1 1 ADP-ribosyltransferase exoenzyme DUF3552 PF12072.3 CBZ55909.1 - 0.0051 16.0 7.3 0.0064 15.7 5.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3552) DUF1186 PF06685.6 CBZ55909.1 - 0.014 14.5 0.7 0.017 14.2 0.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1186) ATP-synt_B PF00430.13 CBZ55909.1 - 0.034 13.9 8.5 0.055 13.2 5.3 1.7 1 1 1 2 2 2 0 ATP synthase B/B' CF(0) HrpE PF06188.7 CBZ55909.1 - 0.067 12.9 1.2 0.087 12.5 0.8 1.3 1 0 0 1 1 1 0 HrpE/YscL/FliH and V-type ATPase subunit E PKK PF12474.3 CBZ55909.1 - 0.097 12.3 5.8 0.19 11.4 3.9 1.5 1 1 0 1 1 1 0 Polo kinase kinase DUF1098 PF06497.6 CBZ55909.1 - 0.1 12.6 1.8 1 9.4 0.2 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF1098) vATP-synt_E PF01991.13 CBZ55909.1 - 0.11 11.7 8.0 0.16 11.2 5.6 1.2 1 0 0 1 1 1 0 ATP synthase (E/31 kDa) subunit Glutaredoxin2_C PF04399.8 CBZ55909.1 - 0.15 11.5 1.9 0.22 11.0 1.3 1.3 1 1 0 1 1 1 0 Glutaredoxin 2, C terminal domain DUF883 PF05957.8 CBZ55909.1 - 1.7 9.0 5.1 17 5.9 0.1 2.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) RILP PF11461.3 CBZ55909.1 - 2.8 8.1 6.2 0.62 10.2 0.7 2.1 1 1 1 2 2 2 0 Rab interacting lysosomal protein RepL PF05732.6 CBZ55910.1 - 0.8 8.8 5.0 0.14 11.3 0.2 2.0 2 0 0 2 2 2 0 Firmicute plasmid replication protein (RepL) BSP_II PF05432.6 CBZ55910.1 - 0.81 8.9 10.1 0.51 9.5 3.9 2.0 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) Tox-SHH PF15652.1 CBZ55910.1 - 3.2 8.4 6.0 0.64 10.6 0.4 2.4 2 1 1 3 3 3 0 HNH/Endo VII superfamily toxin with a SHH signature PBP1_TM PF14812.1 CBZ55910.1 - 4 7.8 16.2 10 6.5 1.2 2.4 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CDC37_C PF08564.5 CBZ55910.1 - 4.6 7.1 8.1 19 5.1 0.1 3.1 3 0 0 3 3 3 0 Cdc37 C terminal domain FAM176 PF14851.1 CBZ55910.1 - 4.9 6.8 8.0 2 8.1 1.0 2.2 2 0 0 2 2 2 0 FAM176 family Herpes_DNAp_acc PF04929.7 CBZ55911.1 - 0.22 10.4 0.1 0.31 9.9 0.1 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Beta-lactamase PF00144.19 CBZ55913.1 - 2.4e-33 115.5 6.8 6.4e-33 114.1 0.1 2.9 3 0 0 3 3 3 2 Beta-lactamase ABC1 PF03109.11 CBZ55913.1 - 3.6e-23 81.8 0.0 6.4e-23 80.9 0.0 1.4 1 0 0 1 1 1 1 ABC1 family WaaY PF06176.6 CBZ55913.1 - 0.0054 15.9 0.0 0.0087 15.3 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide core biosynthesis protein (WaaY) RIO1 PF01163.17 CBZ55913.1 - 0.021 14.2 0.0 0.077 12.3 0.0 1.8 2 0 0 2 2 2 0 RIO1 family Synaptobrevin PF00957.16 CBZ55914.1 - 2.2e-11 43.1 0.1 3.4e-11 42.5 0.0 1.3 1 0 0 1 1 1 1 Synaptobrevin DUF605 PF04652.11 CBZ55914.1 - 0.024 14.0 15.1 0.031 13.6 10.5 1.1 1 0 0 1 1 1 0 Vta1 like G10 PF01125.12 CBZ55915.1 - 2e-55 186.3 12.3 1e-31 109.4 7.5 2.1 2 0 0 2 2 2 2 G10 protein SHS2_Rpb7-N PF03876.12 CBZ55916.1 - 0.00014 21.8 0.0 0.00027 21.0 0.0 1.5 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 AAA_13 PF13166.1 CBZ55917.1 - 1.3 7.4 13.6 2.4 6.4 9.4 1.3 1 1 0 1 1 1 0 AAA domain zf-DHHC PF01529.15 CBZ55918.1 - 3.2e-19 68.9 22.6 9.3e-19 67.4 10.3 2.9 1 1 2 3 3 3 2 DHHC palmitoyltransferase AP2 PF00847.15 CBZ55919.1 - 0.00068 19.7 0.0 0.0015 18.6 0.0 1.6 1 0 0 1 1 1 1 AP2 domain TFIID-31kDa PF02291.10 CBZ55920.1 - 0.0018 18.0 0.1 0.0042 16.8 0.0 1.6 2 0 0 2 2 2 1 Transcription initiation factor IID, 31kD subunit DUF348 PF03990.9 CBZ55920.1 - 0.076 12.5 0.0 0.18 11.4 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF348) Alpha-amylase PF00128.19 CBZ55921.1 - 1e-26 94.1 0.4 1.1e-17 64.3 0.0 2.5 2 1 0 2 2 2 2 Alpha amylase, catalytic domain Alpha-amylase_C PF02806.13 CBZ55921.1 - 5.6e-08 32.8 0.0 1.6e-07 31.3 0.0 1.8 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain hDGE_amylase PF14701.1 CBZ55921.1 - 0.021 13.7 0.0 0.21 10.4 0.0 2.1 2 0 0 2 2 2 0 glucanotransferase domain of human glycogen debranching enzyme Ebp2 PF05890.7 CBZ55924.1 - 1.2e-32 113.3 17.8 1.7e-32 112.7 12.4 1.2 1 0 0 1 1 1 1 Eukaryotic rRNA processing protein EBP2 Dynamitin PF04912.9 CBZ55925.1 - 3.6e-32 111.6 4.5 1.2e-15 57.2 0.1 3.5 4 0 0 4 4 4 3 Dynamitin Nsp1_C PF05064.8 CBZ55925.1 - 1.1 8.8 5.4 0.17 11.5 0.3 2.1 2 0 0 2 2 2 0 Nsp1-like C-terminal region V_ATPase_I PF01496.14 CBZ55925.1 - 2 6.1 3.1 6.2 4.5 2.1 1.7 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family Prefoldin_2 PF01920.15 CBZ55925.1 - 4 7.2 7.2 5.6 6.7 0.5 3.0 2 1 1 3 3 3 0 Prefoldin subunit Spectrin PF00435.16 CBZ55925.1 - 5.7 7.2 12.2 15 5.9 1.1 2.9 1 1 1 2 2 2 0 Spectrin repeat Tetraspannin PF00335.15 CBZ55926.1 - 0.037 13.3 15.7 0.072 12.3 10.9 1.4 1 0 0 1 1 1 0 Tetraspanin family InaF-motif PF15018.1 CBZ55926.1 - 1.2 8.6 9.6 3.4 7.1 6.7 1.7 1 0 0 1 1 1 0 TRP-interacting helix TMCO5 PF14992.1 CBZ55926.1 - 1.9 7.5 4.1 3 6.8 2.8 1.3 1 0 0 1 1 1 0 TMCO5 family TPR_14 PF13428.1 CBZ55927.1 - 2.8e-10 39.8 11.0 0.36 11.5 0.3 8.8 5 4 5 10 10 10 2 Tetratricopeptide repeat TPR_16 PF13432.1 CBZ55927.1 - 3.5e-09 37.0 15.2 0.00014 22.4 0.6 6.7 6 1 1 7 7 6 2 Tetratricopeptide repeat TPR_19 PF14559.1 CBZ55927.1 - 7.1e-09 35.8 5.3 0.0057 16.9 0.1 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.1 CBZ55927.1 - 8.8e-06 25.2 5.8 0.2 11.3 0.7 5.5 5 1 1 6 6 6 2 TPR repeat Apc3 PF12895.2 CBZ55927.1 - 0.00045 20.3 2.0 0.00098 19.2 0.3 2.5 3 0 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.23 CBZ55927.1 - 0.0079 15.7 0.9 1.6 8.4 0.1 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.1 CBZ55927.1 - 0.044 13.7 7.8 5.9 6.9 1.1 4.5 4 2 0 4 4 4 0 Tetratricopeptide repeat TPR_17 PF13431.1 CBZ55927.1 - 0.16 12.2 4.5 11 6.4 0.0 4.7 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_2 PF07719.12 CBZ55927.1 - 0.2 11.6 18.6 0.13 12.2 0.4 6.6 9 0 0 9 9 8 0 Tetratricopeptide repeat TPR_8 PF13181.1 CBZ55927.1 - 0.61 9.9 3.2 1.3 8.9 0.1 3.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.1 CBZ55927.1 - 0.66 9.9 5.5 17 5.5 0.0 5.1 6 0 0 6 6 5 0 Tetratricopeptide repeat MAP7 PF05672.6 CBZ55927.1 - 4.6 6.5 8.0 0.37 10.1 1.0 2.4 3 0 0 3 3 3 0 MAP7 (E-MAP-115) family ACDC PF14733.1 CBZ55929.1 - 2.1e-08 34.1 0.1 7.1e-05 22.8 0.0 2.3 2 0 0 2 2 2 2 AP2-coincident C-terminal PAP2_C PF14360.1 CBZ55930.1 - 7.4e-06 26.1 12.8 0.00052 20.2 0.3 3.2 4 0 0 4 4 4 2 PAP2 superfamily C-terminal PAP2 PF01569.16 CBZ55930.1 - 0.29 10.7 10.8 0.89 9.2 0.1 2.6 2 0 0 2 2 2 0 PAP2 superfamily ELF PF03317.8 CBZ55930.1 - 0.4 9.9 2.5 0.84 8.8 1.8 1.4 1 0 0 1 1 1 0 ELF protein Peptidase_S9 PF00326.16 CBZ55931.1 - 1.8e-28 99.2 0.0 3e-28 98.5 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 CBZ55931.1 - 7.5e-09 35.8 2.0 2.2e-08 34.2 1.4 1.8 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CBZ55931.1 - 3.5e-06 26.8 0.1 7.8e-06 25.6 0.1 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CBZ55931.1 - 0.0052 16.3 0.0 0.011 15.2 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 CBZ55931.1 - 0.028 14.2 0.0 0.058 13.2 0.0 1.6 1 0 0 1 1 1 0 Putative lysophospholipase Esterase PF00756.15 CBZ55931.1 - 0.047 13.1 0.0 0.088 12.2 0.0 1.3 1 0 0 1 1 1 0 Putative esterase DLH PF01738.13 CBZ55931.1 - 0.047 12.9 0.0 0.4 9.9 0.0 2.1 2 0 0 2 2 2 0 Dienelactone hydrolase family SET PF00856.23 CBZ55932.1 - 1.2e-10 41.9 0.1 2.4e-10 40.9 0.0 1.9 1 1 0 1 1 1 1 SET domain zf-MYND PF01753.13 CBZ55932.1 - 0.00018 21.3 1.8 0.00018 21.3 1.3 2.2 2 0 0 2 2 2 1 MYND finger Pyr_redox_2 PF07992.9 CBZ55933.1 - 7.3e-40 137.0 0.5 1.4e-39 136.0 0.4 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.17 CBZ55933.1 - 9e-31 106.1 0.9 1.7e-30 105.2 0.6 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.22 CBZ55933.1 - 9.1e-18 64.4 2.1 2.5e-16 59.8 0.0 2.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 CBZ55933.1 - 3.7e-09 36.9 0.2 1.4e-07 31.8 0.0 2.2 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 CBZ55933.1 - 1.4e-05 24.4 0.4 0.0015 17.6 0.1 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.9 CBZ55933.1 - 4.6e-05 22.0 4.1 0.034 12.6 0.1 3.4 3 1 1 4 4 4 2 HI0933-like protein 3HCDH_N PF02737.13 CBZ55933.1 - 0.00034 20.3 1.8 0.0015 18.2 0.0 2.3 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GIDA PF01134.17 CBZ55933.1 - 0.00098 18.0 1.8 0.0042 16.0 0.5 2.4 2 1 0 2 2 2 1 Glucose inhibited division protein A 2-Hacid_dh_C PF02826.14 CBZ55933.1 - 0.0015 17.7 1.3 0.062 12.4 0.0 2.8 3 0 0 3 3 3 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FAD_binding_2 PF00890.19 CBZ55933.1 - 0.0046 15.8 7.4 0.13 11.1 0.2 2.5 1 1 1 2 2 2 2 FAD binding domain K_oxygenase PF13434.1 CBZ55933.1 - 0.0095 14.8 0.0 0.028 13.3 0.0 1.8 1 1 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_Gly3P_dh_N PF01210.18 CBZ55933.1 - 0.027 14.2 0.4 0.46 10.1 0.0 2.4 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_8 PF13450.1 CBZ55933.1 - 0.034 14.1 2.7 0.078 13.0 1.9 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain XdhC_C PF13478.1 CBZ55933.1 - 0.13 12.5 0.4 20 5.5 0.1 2.4 2 0 0 2 2 2 0 XdhC Rossmann domain DAO PF01266.19 CBZ55933.1 - 0.14 11.0 6.5 0.22 10.3 1.7 3.0 2 1 2 4 4 4 0 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.16 CBZ55933.1 - 1 8.8 5.3 0.51 9.8 0.1 2.7 3 0 0 3 3 3 0 Alanine dehydrogenase/PNT, C-terminal domain EF-hand_1 PF00036.27 CBZ55934.1 - 5e-14 50.4 1.7 1.1e-05 24.3 0.0 3.2 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.1 CBZ55934.1 - 6.3e-14 50.5 1.0 1.5e-06 27.5 0.1 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.1 CBZ55934.1 - 9.7e-13 46.8 1.3 1.3e-06 27.5 0.0 2.5 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.1 CBZ55934.1 - 1e-11 44.7 0.7 1.9e-10 40.7 0.5 2.3 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.1 CBZ55934.1 - 4e-11 42.3 0.9 0.0002 20.8 0.0 3.2 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_like PF09279.6 CBZ55934.1 - 0.0079 16.1 0.2 2.5 8.1 0.0 2.2 2 0 0 2 2 2 2 Phosphoinositide-specific phospholipase C, efhand-like EF-hand_10 PF14788.1 CBZ55934.1 - 0.01 15.4 0.1 0.3 10.7 0.0 2.4 2 0 0 2 2 2 0 EF hand EF-hand_4 PF12763.2 CBZ55934.1 - 0.017 14.8 0.0 2.7 7.7 0.0 2.5 2 1 1 3 3 3 0 Cytoskeletal-regulatory complex EF hand Toprim PF01751.17 CBZ55934.1 - 0.089 12.7 0.0 7.6 6.5 0.0 2.2 1 1 1 2 2 2 0 Toprim domain ERM PF00769.14 CBZ55936.1 - 9.1e-05 22.1 10.6 0.00016 21.3 7.4 1.4 1 0 0 1 1 1 1 Ezrin/radixin/moesin family V_ATPase_I PF01496.14 CBZ55936.1 - 0.35 8.6 0.5 0.43 8.3 0.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family C_GCAxxG_C_C PF09719.5 CBZ55936.1 - 0.75 9.6 5.8 66 3.3 2.8 3.1 2 1 0 2 2 2 0 Putative redox-active protein (C_GCAxxG_C_C) YlqD PF11068.3 CBZ55936.1 - 3 7.8 9.8 5.4 7.0 6.8 1.4 1 0 0 1 1 1 0 YlqD protein Lactamase_B_2 PF12706.2 CBZ55937.1 - 5.7e-12 45.5 0.0 6e-05 22.6 0.0 2.3 2 0 0 2 2 2 2 Beta-lactamase superfamily domain Lactamase_B PF00753.22 CBZ55937.1 - 1.1e-09 38.1 0.3 5e-09 36.0 0.0 2.1 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily DNA_pol_A_exo1 PF01612.15 CBZ55938.1 - 1.4e-38 132.1 0.0 2e-38 131.6 0.0 1.2 1 0 0 1 1 1 1 3'-5' exonuclease HRDC PF00570.18 CBZ55938.1 - 2.9e-08 33.2 0.1 8.5e-08 31.8 0.1 1.8 1 0 0 1 1 1 1 HRDC domain Humanin PF15040.1 CBZ55938.1 - 0.59 9.4 2.3 0.35 10.1 0.0 1.8 2 0 0 2 2 2 0 Humanin family Glycos_transf_1 PF00534.15 CBZ55939.1 - 3.7e-08 32.9 0.0 0.00012 21.5 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferases group 1 Ribosomal_60s PF00428.14 CBZ55940.1 - 5.4 7.4 9.7 0.57 10.6 1.9 3.0 3 0 0 3 3 3 0 60s Acidic ribosomal protein TPR_11 PF13414.1 CBZ55941.1 - 4.7e-19 67.7 8.3 5.7e-07 29.0 0.2 3.5 2 1 1 3 3 3 3 TPR repeat TPR_1 PF00515.23 CBZ55941.1 - 5.6e-09 35.2 2.3 0.016 14.8 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 CBZ55941.1 - 5.9e-07 28.9 1.9 0.38 10.7 0.4 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_7 PF13176.1 CBZ55941.1 - 0.0042 16.7 1.1 0.011 15.5 0.2 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 CBZ55941.1 - 0.045 13.7 3.0 0.12 12.3 0.1 2.5 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.1 CBZ55941.1 - 0.12 12.5 1.7 2.2 8.6 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF4483 PF14825.1 CBZ55942.1 - 0.0085 15.7 0.0 21 4.7 0.0 3.3 2 1 1 3 3 3 3 Domain of unknown function (DUF4483) TFIIF_alpha PF05793.7 CBZ55943.1 - 1.1 7.4 28.5 1.8 6.8 19.8 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) TMEM247 PF15444.1 CBZ55943.1 - 7.1 6.3 7.5 11 5.7 5.2 1.4 1 0 0 1 1 1 0 Transmembrane protein 247 Ubiquitin_3 PF14836.1 CBZ55944.1 - 0.047 13.3 0.2 0.074 12.7 0.1 1.3 1 0 0 1 1 1 0 Ubiquitin-like domain SlyX PF04102.7 CBZ55944.1 - 0.061 13.7 0.3 0.061 13.7 0.2 2.0 3 0 0 3 3 3 0 SlyX Fib_alpha PF08702.5 CBZ55944.1 - 0.11 12.6 0.5 0.2 11.8 0.4 1.3 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF2730 PF10805.3 CBZ55946.1 - 0.23 11.2 8.5 0.099 12.3 0.2 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2730) H_lectin PF09458.5 CBZ55947.1 - 0.00011 21.8 0.0 0.00036 20.1 0.0 1.9 1 0 0 1 1 1 1 H-type lectin domain CMS1 PF14617.1 CBZ55947.1 - 0.98 8.4 0.0 1.7 7.6 0.0 1.3 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit NUDIX PF00293.23 CBZ55948.1 - 0.0013 18.3 0.0 0.0026 17.3 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain EF-hand_1 PF00036.27 CBZ55949.1 - 1.9e-33 111.1 16.6 3.5e-09 35.2 0.8 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 CBZ55949.1 - 1.8e-28 98.4 9.3 8e-16 57.9 0.2 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 CBZ55949.1 - 1.5e-26 89.8 10.6 3.1e-09 35.9 0.1 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.1 CBZ55949.1 - 2.7e-25 87.7 14.9 5.5e-14 51.5 0.7 3.7 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.1 CBZ55949.1 - 1e-19 68.9 18.4 3.9e-05 22.7 0.3 4.5 4 1 1 5 5 5 4 EF hand EF-hand_9 PF14658.1 CBZ55949.1 - 1.2e-13 50.7 0.1 5.9e-07 29.2 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.2 CBZ55949.1 - 4.6e-08 32.7 6.5 0.01 15.5 0.4 3.3 1 1 2 3 3 3 3 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 CBZ55949.1 - 0.004 17.1 0.1 1.5 8.8 0.0 2.1 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region DUF21 PF01595.15 CBZ55949.1 - 0.048 12.9 1.4 0.41 9.9 0.4 2.1 2 0 0 2 2 2 0 Domain of unknown function DUF21 DUF853 PF05872.7 CBZ55949.1 - 0.056 11.7 0.1 0.5 8.6 0.0 1.9 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF853) SRI PF08236.6 CBZ55949.1 - 0.059 13.3 0.2 0.59 10.1 0.0 2.2 2 0 0 2 2 2 0 SRI (Set2 Rpb1 interacting) domain FlgD PF03963.9 CBZ55949.1 - 0.069 13.2 0.1 0.22 11.6 0.0 1.9 2 1 0 2 2 2 0 Flagellar hook capping protein - N-terminal region TBPIP PF07106.8 CBZ55949.1 - 0.076 12.5 0.9 1.1 8.8 0.1 2.1 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) TerB PF05099.8 CBZ55949.1 - 0.084 12.6 1.4 2.5 7.8 0.1 2.5 2 1 0 2 2 2 0 Tellurite resistance protein TerB Toprim_2 PF13155.1 CBZ55949.1 - 0.091 13.0 2.1 9.9 6.5 0.1 2.5 1 1 1 2 2 2 0 Toprim-like Caleosin PF05042.8 CBZ55949.1 - 0.12 11.8 0.1 1.8 8.0 0.0 2.2 2 0 0 2 2 2 0 Caleosin related protein MgtE_N PF03448.12 CBZ55949.1 - 0.22 11.8 4.0 0.2 12.0 0.5 2.3 2 0 0 2 2 2 0 MgtE intracellular N domain EF-hand_10 PF14788.1 CBZ55949.1 - 0.34 10.5 3.9 1.5 8.5 0.7 2.9 3 0 0 3 3 3 0 EF hand Excalibur PF05901.6 CBZ55949.1 - 5.7 7.3 5.7 4.7 7.6 0.1 2.7 2 1 0 2 2 2 0 Excalibur calcium-binding domain Peptidase_C12 PF01088.16 CBZ55950.1 - 1.3e-58 197.7 0.7 1.9e-58 197.1 0.0 1.6 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase, family 1 FAD_syn PF06574.7 CBZ55950.1 - 0.036 13.7 0.0 0.46 10.0 0.0 2.2 2 0 0 2 2 2 0 FAD synthetase WD40 PF00400.27 CBZ55951.1 - 2.2e-19 68.5 9.0 6.5e-07 28.9 0.0 5.5 6 0 0 6 6 6 3 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 CBZ55951.1 - 3e-05 23.8 0.0 7.7e-05 22.5 0.0 1.7 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex DASH_Dam1 PF08653.5 CBZ55952.1 - 0.35 10.6 0.5 9.1 6.1 0.0 2.9 3 0 0 3 3 3 0 DASH complex subunit Dam1 Methyltransf_3 PF01596.12 CBZ55953.1 - 1.6e-14 53.4 0.0 9.1e-05 21.5 0.0 4.2 4 0 0 4 4 4 4 O-methyltransferase Rhodanese PF00581.15 CBZ55953.1 - 7.2e-08 32.7 0.0 0.004 17.4 0.0 2.7 2 0 0 2 2 2 2 Rhodanese-like domain Methyltransf_24 PF13578.1 CBZ55953.1 - 0.00019 22.1 0.9 0.76 10.6 0.0 3.7 1 1 0 2 2 2 2 Methyltransferase domain CPW_WPC PF09717.5 CBZ55956.1 - 2.8e-32 111.1 14.5 1.1e-16 61.1 2.5 3.1 3 0 0 3 3 3 3 Plasmodium falciparum domain of unknown function (CPW_WPC) SLBP_RNA_bind PF15247.1 CBZ55957.1 - 4e-24 84.1 3.7 1e-23 82.8 2.6 1.7 1 0 0 1 1 1 1 Histone RNA hairpin-binding protein RNA-binding domain Symplekin_C PF12295.3 CBZ55958.1 - 4.3e-46 157.1 0.2 1e-45 155.9 0.2 1.7 1 0 0 1 1 1 1 Symplekin tight junction protein C terminal Thioredoxin PF00085.15 CBZ55960.1 - 3.5e-27 94.1 0.0 5.1e-27 93.5 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 CBZ55960.1 - 1.5e-07 31.6 0.0 1.4e-06 28.4 0.0 2.1 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.1 CBZ55960.1 - 2.6e-05 24.1 0.0 4.6e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_6 PF13848.1 CBZ55960.1 - 6.5e-05 22.8 0.0 0.00011 22.0 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 CBZ55960.1 - 0.0002 21.3 0.1 0.028 14.5 0.0 2.4 1 1 1 2 2 2 1 Thioredoxin-like Thioredoxin_3 PF13192.1 CBZ55960.1 - 0.0016 18.1 0.0 0.0026 17.5 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin domain Redoxin PF08534.5 CBZ55960.1 - 0.12 11.8 0.0 0.2 11.1 0.0 1.4 1 0 0 1 1 1 0 Redoxin RskA PF10099.4 CBZ55960.1 - 0.18 11.4 1.9 0.27 10.9 1.3 1.2 1 0 0 1 1 1 0 Anti-sigma-K factor rskA DUF3789 PF12664.2 CBZ55960.1 - 0.26 10.6 4.8 0.59 9.4 3.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3789) PAP2 PF01569.16 CBZ55961.1 - 1e-22 80.1 3.4 2.2e-22 79.0 2.4 1.5 1 0 0 1 1 1 1 PAP2 superfamily SAND PF01342.16 CBZ55961.1 - 0.068 12.8 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 SAND domain PAP2_C PF14360.1 CBZ55961.1 - 0.36 11.1 6.1 1.1 9.5 1.8 2.9 2 1 0 2 2 2 0 PAP2 superfamily C-terminal PKD_channel PF08016.7 CBZ55962.1 - 3.5e-13 48.7 59.6 2.3e-09 36.2 11.4 5.3 5 1 0 5 5 5 4 Polycystin cation channel TEX13 PF15186.1 CBZ55962.1 - 1.4 8.5 8.9 2.3 7.7 3.9 2.4 2 0 0 2 2 2 0 Testis-expressed sequence 13 protein family CDC50 PF03381.10 CBZ55963.1 - 2e-31 109.1 0.0 3.4e-31 108.4 0.0 1.3 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family Hydrolase PF00702.21 CBZ55965.1 - 1.9e-13 51.3 1.0 3.9e-10 40.4 0.8 3.3 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 CBZ55965.1 - 1.2e-12 48.4 0.0 3.4e-12 46.9 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 CBZ55965.1 - 5.4e-09 35.4 1.8 1.5e-08 34.0 0.0 2.6 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase_like2 PF13246.1 CBZ55965.1 - 1.7e-05 24.7 0.0 4.6e-05 23.2 0.0 1.8 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 CBZ55965.1 - 0.0014 18.2 0.1 0.0055 16.3 0.0 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase AP2 PF00847.15 CBZ55966.1 - 5.9e-09 35.9 1.7 1.3e-06 28.4 0.1 3.5 3 0 0 3 3 3 2 AP2 domain Pkinase PF00069.20 CBZ55967.1 - 2.8e-34 118.4 0.0 3.5e-34 118.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ55967.1 - 1.3e-13 50.5 0.0 1.7e-13 50.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CBZ55967.1 - 4.7e-06 26.5 0.4 0.0025 17.6 0.2 2.8 1 1 1 2 2 2 2 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 CBZ55967.1 - 0.18 11.1 0.1 0.44 9.8 0.1 1.5 1 1 1 2 2 2 0 PhoP regulatory network protein YrbL Kdo PF06293.9 CBZ55967.1 - 0.21 10.6 0.1 0.33 9.9 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family ACDC PF14733.1 CBZ55968.1 - 3.7e-20 71.8 0.4 5.7e-20 71.2 0.3 1.2 1 0 0 1 1 1 1 AP2-coincident C-terminal AP2 PF00847.15 CBZ55968.1 - 8.2e-11 41.8 0.1 8.2e-11 41.8 0.1 3.9 4 0 0 4 4 4 2 AP2 domain Methyltransf_18 PF12847.2 CBZ55969.1 - 6.8e-06 26.6 0.0 0.00017 22.1 0.0 2.6 3 0 0 3 3 3 1 Methyltransferase domain Met_10 PF02475.11 CBZ55969.1 - 8.3e-06 25.5 0.0 1.4e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein RrnaAD PF00398.15 CBZ55969.1 - 7.3e-05 21.9 0.0 0.00011 21.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase tRNA_U5-meth_tr PF05958.6 CBZ55969.1 - 8.5e-05 21.3 0.0 0.17 10.5 0.0 2.9 3 0 0 3 3 3 2 tRNA (Uracil-5-)-methyltransferase Cons_hypoth95 PF03602.10 CBZ55969.1 - 0.022 14.1 0.0 0.058 12.7 0.0 1.7 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Methyltransf_15 PF09445.5 CBZ55969.1 - 0.079 12.5 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Methyltransf_26 PF13659.1 CBZ55969.1 - 0.1 12.6 0.0 0.37 10.8 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.1 CBZ55969.1 - 0.11 12.1 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Sec16_C PF12931.2 CBZ55970.1 - 0.098 12.3 0.1 0.41 10.3 0.0 1.8 2 0 0 2 2 2 0 Sec23-binding domain of Sec16 Phage_Mu_Gam PF07352.7 CBZ55970.1 - 2.7 7.5 7.1 11 5.5 1.1 2.6 2 1 0 2 2 2 0 Bacteriophage Mu Gam like protein ANAPC15 PF15243.1 CBZ55970.1 - 3.1 7.9 8.1 1.3 9.1 0.2 2.6 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 15 AMP-binding PF00501.23 CBZ55971.1 - 2.4e-69 233.7 0.1 4.5e-53 180.1 0.0 2.3 2 0 0 2 2 2 2 AMP-binding enzyme DUF1361 PF07099.6 CBZ55972.1 - 0.02 14.6 0.1 0.051 13.3 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1361) Claudin_3 PF06653.6 CBZ55973.1 - 0.0013 18.4 0.9 0.0019 17.9 0.6 1.2 1 0 0 1 1 1 1 Tight junction protein, Claudin-like DUF2975 PF11188.3 CBZ55973.1 - 1 9.0 4.8 1.8 8.3 3.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2975) Cation_ATPase_C PF00689.16 CBZ55973.1 - 1.9 7.9 10.3 3.5 7.1 0.7 2.1 1 1 1 2 2 2 0 Cation transporting ATPase, C-terminus VRR_NUC PF08774.6 CBZ55974.1 - 1.3e-11 44.4 0.0 3.3e-11 43.0 0.0 1.7 1 0 0 1 1 1 1 VRR-NUC domain EF-hand_8 PF13833.1 CBZ55975.1 - 1.2e-05 24.7 0.0 0.028 14.0 0.0 3.9 4 0 0 4 4 4 2 EF-hand domain pair EF-hand_1 PF00036.27 CBZ55975.1 - 1.3e-05 24.1 0.0 1.1 8.7 0.0 4.6 4 0 0 4 4 4 2 EF hand EF-hand_6 PF13405.1 CBZ55975.1 - 0.00017 21.1 0.0 4.2 7.5 0.0 4.5 5 0 0 5 5 5 2 EF-hand domain AKAP28 PF14469.1 CBZ55975.1 - 0.00031 20.2 0.0 0.79 9.3 0.0 2.4 2 0 0 2 2 2 2 28 kDa A-kinase anchor EF-hand_7 PF13499.1 CBZ55975.1 - 0.00079 19.5 0.0 5.6 7.1 0.0 4.0 4 0 0 4 4 4 2 EF-hand domain pair EF-hand_9 PF14658.1 CBZ55975.1 - 0.06 13.2 0.0 9.5 6.2 0.0 3.0 3 0 0 3 3 3 0 EF-hand domain Silic_transp PF03842.8 CBZ55975.1 - 0.086 10.9 0.7 0.16 10.0 0.0 1.7 2 0 0 2 2 2 0 Silicon transporter Methyltransf_11 PF08241.7 CBZ55976.1 - 1.1e-20 73.8 0.0 2e-20 73.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CBZ55976.1 - 4.3e-14 52.3 0.0 5.7e-14 51.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 CBZ55976.1 - 2.7e-13 49.5 0.0 3.7e-13 49.1 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.1 CBZ55976.1 - 2.2e-12 46.9 0.0 3.1e-12 46.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CBZ55976.1 - 2.5e-12 47.1 0.0 5e-12 46.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CBZ55976.1 - 1.6e-11 44.4 0.0 4.2e-11 43.0 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 CBZ55976.1 - 1.6e-11 44.7 0.0 2.9e-11 43.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 CBZ55976.1 - 9.3e-08 32.1 0.0 6.1e-07 29.4 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain MetW PF07021.7 CBZ55976.1 - 9.5e-06 25.1 0.0 2e-05 24.0 0.0 1.5 1 1 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_8 PF05148.10 CBZ55976.1 - 0.00074 19.2 0.0 0.0016 18.1 0.0 1.5 1 0 0 1 1 1 1 Hypothetical methyltransferase MTS PF05175.9 CBZ55976.1 - 0.001 18.5 0.0 0.0017 17.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.14 CBZ55976.1 - 0.042 13.3 0.0 0.061 12.8 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) FtsJ PF01728.14 CBZ55976.1 - 0.13 12.2 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase RrnaAD PF00398.15 CBZ55976.1 - 0.15 11.0 0.0 0.2 10.6 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase SNARE PF05739.14 CBZ55977.1 - 1.9e-17 62.6 5.0 1.9e-17 62.6 3.5 2.6 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.20 CBZ55977.1 - 2.2e-08 34.1 0.6 2.2e-08 34.1 0.4 2.4 2 0 0 2 2 2 1 Syntaxin GST_C PF00043.20 CBZ55977.1 - 0.017 15.1 0.4 0.5 10.3 0.0 2.5 1 1 0 2 2 2 0 Glutathione S-transferase, C-terminal domain POTRA_2 PF08479.6 CBZ55977.1 - 0.038 13.6 0.3 1.6 8.4 0.1 2.7 2 0 0 2 2 2 0 POTRA domain, ShlB-type Synaptobrevin PF00957.16 CBZ55977.1 - 0.13 11.9 4.3 0.54 9.8 1.1 2.5 2 0 0 2 2 2 0 Synaptobrevin DUF912 PF06024.7 CBZ55977.1 - 0.14 12.2 0.3 0.14 12.2 0.2 1.8 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Adaptin_binding PF10199.4 CBZ55977.1 - 0.63 10.3 6.9 7.7 6.8 1.1 2.5 2 1 0 2 2 2 0 Alpha and gamma adaptin binding protein p34 Wbp11 PF09429.5 CBZ55977.1 - 6.3 6.8 11.3 1.5 8.8 0.2 3.6 2 1 2 4 4 4 0 WW domain binding protein 11 UPF0197 PF05251.7 CBZ55982.1 - 5.1e-14 52.3 6.0 5.1e-14 52.3 4.1 1.6 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0197) DUF1705 PF08019.7 CBZ55982.1 - 0.19 11.1 8.8 0.54 9.7 1.4 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1705) Claudin_3 PF06653.6 CBZ55982.1 - 5.7 6.6 10.0 0.06 13.0 1.5 1.7 2 0 0 2 2 2 0 Tight junction protein, Claudin-like Synaptobrevin PF00957.16 CBZ55983.1 - 1.3e-26 91.9 0.0 1.8e-26 91.5 0.0 1.2 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.1 CBZ55983.1 - 4.8e-07 29.2 0.0 8e-07 28.5 0.0 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain SecE PF00584.15 CBZ55983.1 - 0.024 14.2 0.1 0.051 13.1 0.1 1.5 1 0 0 1 1 1 0 SecE/Sec61-gamma subunits of protein translocation complex Maf1 PF09174.5 CBZ55984.1 - 7.4e-18 65.0 0.0 7.5e-15 55.2 0.0 2.5 2 0 0 2 2 2 2 Maf1 regulator SWIB PF02201.13 CBZ55985.1 - 0.0068 16.0 0.0 0.036 13.7 0.0 2.2 2 0 0 2 2 2 1 SWIB/MDM2 domain SPG48 PF14764.1 CBZ55988.1 - 5.7e-58 196.5 16.4 7.4e-56 189.5 2.7 3.0 3 0 0 3 3 3 2 AP-5 complex subunit, vesicle trafficking Ku PF02735.11 CBZ55989.1 - 1.2e-15 57.4 0.0 5.5e-15 55.3 0.0 1.9 1 1 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.10 CBZ55989.1 - 1.1e-07 31.4 0.0 2.1e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Ku_C PF03730.9 CBZ55989.1 - 0.0026 18.2 0.0 0.0088 16.5 0.0 1.9 1 0 0 1 1 1 1 Ku70/Ku80 C-terminal arm PBP1_TM PF14812.1 CBZ55989.1 - 0.61 10.4 5.5 1.9 8.8 3.8 1.8 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal PSK PF06404.7 CBZ55989.1 - 0.8 10.5 2.6 2.9 8.7 1.8 1.9 1 0 0 1 1 1 0 Phytosulfokine precursor protein (PSK) Daxx PF03344.10 CBZ55990.1 - 3e-07 29.3 16.6 3e-07 29.3 11.5 3.4 4 0 0 4 4 4 1 Daxx Family TFIIA PF03153.8 CBZ55990.1 - 0.00039 20.4 11.4 0.00039 20.4 7.9 3.1 3 1 0 3 3 3 1 Transcription factor IIA, alpha/beta subunit Ycf1 PF05758.7 CBZ55990.1 - 0.0017 16.1 4.1 0.0017 16.1 2.8 2.2 2 0 0 2 2 2 1 Ycf1 DUF3071 PF11268.3 CBZ55991.1 - 0.12 12.1 8.2 0.15 11.8 5.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3071) CAF-1_p150 PF11600.3 CBZ55991.1 - 0.36 10.1 6.7 0.5 9.7 4.6 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF2217 PF10265.4 CBZ55991.1 - 0.51 9.0 8.2 0.64 8.7 5.7 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) Macoilin PF09726.4 CBZ55991.1 - 0.82 7.8 11.6 0.96 7.6 8.1 1.2 1 0 0 1 1 1 0 Transmembrane protein RAP1 PF07218.6 CBZ55991.1 - 1.3 6.9 10.5 1.6 6.7 7.3 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Herpes_UL25 PF01499.11 CBZ55991.1 - 3.4 5.8 8.0 4.4 5.4 5.5 1.1 1 0 0 1 1 1 0 Herpesvirus UL25 family Ribosomal_L7Ae PF01248.21 CBZ55992.1 - 0.17 11.3 0.6 2 7.9 0.0 2.3 2 0 0 2 2 2 0 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RrnaAD PF00398.15 CBZ55993.1 - 6.7e-43 146.6 0.0 3.6e-22 78.6 0.0 2.1 1 1 1 2 2 2 2 Ribosomal RNA adenine dimethylase Methyltransf_31 PF13847.1 CBZ55993.1 - 1.5e-06 27.9 0.0 2.4e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CBZ55993.1 - 2.3e-05 24.9 0.0 3.6e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 CBZ55993.1 - 3.3e-05 23.8 0.1 6.4e-05 22.9 0.1 1.5 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 CBZ55993.1 - 4.3e-05 22.7 0.0 6.9e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.7 CBZ55993.1 - 4.6e-05 23.8 0.0 0.00018 21.9 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 CBZ55993.1 - 0.00028 20.3 0.0 0.00042 19.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_11 PF08241.7 CBZ55993.1 - 0.00031 21.1 0.0 0.00062 20.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CBZ55993.1 - 0.00078 19.7 0.0 0.0017 18.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CBZ55993.1 - 0.00083 19.1 0.0 0.0011 18.6 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 CBZ55993.1 - 0.0096 15.4 0.0 0.015 14.8 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_4 PF02390.12 CBZ55993.1 - 0.01 14.9 0.0 0.015 14.3 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase DREV PF05219.7 CBZ55993.1 - 0.012 14.4 0.0 0.019 13.8 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase LCM PF04072.9 CBZ55993.1 - 0.068 12.7 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Leucine carboxyl methyltransferase Methyltransf_32 PF13679.1 CBZ55993.1 - 0.09 12.4 0.0 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain GAS PF13851.1 CBZ55995.1 - 5.3e-37 126.9 26.4 5.3e-37 126.9 18.3 2.3 1 1 1 2 2 2 1 Growth-arrest specific micro-tubule binding PP-binding_2 PF14573.1 CBZ55995.1 - 0.057 13.4 0.1 0.2 11.6 0.0 1.9 1 0 0 1 1 1 0 Acyl-carrier Synaptobrevin PF00957.16 CBZ55995.1 - 0.23 11.0 2.3 0.68 9.5 1.6 1.9 1 0 0 1 1 1 0 Synaptobrevin LRR_4 PF12799.2 CBZ55996.1 - 2.9e-14 52.3 2.6 4.3e-06 26.2 0.0 3.9 4 0 0 4 4 4 3 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 CBZ55996.1 - 0.00077 19.2 2.9 1.2 9.4 0.0 4.0 4 0 0 4 4 4 2 Leucine Rich repeat LRR_8 PF13855.1 CBZ55996.1 - 0.0068 16.1 7.3 0.14 11.8 0.6 3.2 1 1 2 3 3 3 3 Leucine rich repeat LRR_1 PF00560.28 CBZ55996.1 - 0.32 11.1 10.0 8.9 6.7 0.1 4.7 3 1 0 3 3 3 0 Leucine Rich Repeat PHF5 PF03660.9 CBZ55997.1 - 1.9e-49 166.1 12.8 2.1e-49 166.0 8.9 1.0 1 0 0 1 1 1 1 PHF5-like protein PolC_DP2 PF03833.8 CBZ55997.1 - 2.3 5.7 9.5 2.5 5.6 6.6 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 DZR PF12773.2 CBZ55997.1 - 3.3 7.6 17.9 8.8 6.2 3.4 2.8 1 1 1 2 2 2 0 Double zinc ribbon zf-CCCH PF00642.19 CBZ55999.1 - 0.005 16.4 1.5 0.01 15.5 1.0 1.6 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) WD40 PF00400.27 CBZ56000.1 - 2.7e-13 49.2 10.3 6.6e-05 22.6 0.0 6.8 7 0 0 7 7 7 3 WD domain, G-beta repeat Hira PF07569.6 CBZ56000.1 - 0.15 11.2 0.1 0.3 10.2 0.1 1.4 1 0 0 1 1 1 0 TUP1-like enhancer of split IKI3 PF04762.7 CBZ56000.1 - 7.2 4.2 0.0 12 3.5 0.0 1.2 1 0 0 1 1 1 0 IKI3 family CAF-1_p150 PF11600.3 CBZ56001.1 - 0.00027 20.4 32.3 0.00027 20.4 22.4 3.1 4 0 0 4 4 4 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal Ribosomal_L10 PF00466.15 CBZ56001.1 - 0.0028 17.5 0.2 0.016 15.1 0.1 2.2 2 0 0 2 2 2 1 Ribosomal protein L10 PXA PF02194.10 CBZ56001.1 - 1.9 8.0 10.5 9.6 5.7 0.0 2.6 2 0 0 2 2 2 0 PXA domain Phlebovirus_NSM PF07246.6 CBZ56001.1 - 3.6 6.6 9.5 6.4 5.8 6.6 1.3 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M Ndc1_Nup PF09531.5 CBZ56001.1 - 7.7 4.8 18.0 12 4.2 12.4 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Snf7 PF03357.16 CBZ56002.1 - 3.3e-29 101.4 6.8 4.1e-29 101.1 4.7 1.1 1 0 0 1 1 1 1 Snf7 Mito_carr PF00153.22 CBZ56003.1 - 3e-55 183.9 2.9 1.6e-18 66.1 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Sporozoite_P67 PF05642.6 CBZ56003.1 - 0.0008 17.4 0.3 0.0011 16.9 0.2 1.1 1 0 0 1 1 1 1 Sporozoite P67 surface antigen zf-RING_2 PF13639.1 CBZ56004.1 - 1e-07 31.6 9.7 2e-07 30.6 6.7 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 CBZ56004.1 - 1.7e-07 31.0 9.3 2.9e-07 30.4 6.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBZ56004.1 - 1.2e-05 24.8 8.8 2.6e-05 23.8 6.1 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 CBZ56004.1 - 1.4e-05 24.8 6.8 3.9e-05 23.4 4.8 1.8 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.1 CBZ56004.1 - 5.1e-05 22.8 7.1 8.3e-05 22.1 4.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CBZ56004.1 - 0.00012 21.6 8.0 0.00021 20.8 5.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 CBZ56004.1 - 0.0033 17.5 7.4 0.0083 16.2 5.2 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger zf-RING_UBOX PF13445.1 CBZ56004.1 - 0.013 15.1 1.9 0.015 15.0 0.4 1.9 1 1 0 1 1 1 0 RING-type zinc-finger DUF3357 PF11837.3 CBZ56004.1 - 0.14 12.0 1.4 3.7 7.4 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3357) zf-Nse PF11789.3 CBZ56004.1 - 0.14 11.6 1.9 0.22 11.0 1.3 1.3 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-Apc11 PF12861.2 CBZ56004.1 - 0.37 10.6 7.8 1 9.2 5.4 1.8 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Ras PF00071.17 CBZ56005.1 - 2.8e-51 173.1 0.0 3.4e-51 172.8 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CBZ56005.1 - 7.3e-16 58.7 0.0 1.4e-15 57.8 0.0 1.5 2 0 0 2 2 1 1 Miro-like protein Arf PF00025.16 CBZ56005.1 - 6.1e-14 51.6 0.0 7.5e-14 51.3 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 CBZ56005.1 - 3.3e-05 23.1 0.0 4.2e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RNA_helicase PF00910.17 CBZ56005.1 - 0.00071 19.7 0.3 0.0046 17.1 0.2 2.0 1 1 0 1 1 1 1 RNA helicase MMR_HSR1 PF01926.18 CBZ56005.1 - 0.0047 16.8 0.0 0.0095 15.8 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.15 CBZ56005.1 - 0.0089 14.7 0.2 0.85 8.2 0.1 2.9 2 1 1 3 3 3 1 G-protein alpha subunit GTP_EFTU PF00009.22 CBZ56005.1 - 0.016 14.6 0.7 0.36 10.2 0.0 2.1 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 CBZ56005.1 - 0.021 14.9 0.1 0.14 12.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain DUF258 PF03193.11 CBZ56005.1 - 0.06 12.5 0.0 0.098 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_16 PF13191.1 CBZ56005.1 - 0.066 13.1 0.1 0.14 12.1 0.0 1.6 2 0 0 2 2 2 0 AAA ATPase domain PduV-EutP PF10662.4 CBZ56005.1 - 0.085 12.3 0.0 0.3 10.5 0.0 1.8 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Septin PF00735.13 CBZ56005.1 - 0.086 11.8 0.2 0.23 10.4 0.0 1.7 2 0 0 2 2 2 0 Septin ATP_bind_1 PF03029.12 CBZ56005.1 - 0.098 12.1 0.1 7 6.1 0.0 2.2 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein NB-ARC PF00931.17 CBZ56005.1 - 0.1 11.4 0.1 0.2 10.4 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA_5 PF07728.9 CBZ56005.1 - 0.14 11.9 0.1 0.33 10.6 0.1 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) NTPase_1 PF03266.10 CBZ56005.1 - 0.14 11.8 0.2 0.23 11.1 0.1 1.4 1 0 0 1 1 1 0 NTPase NACHT PF05729.7 CBZ56005.1 - 0.14 11.7 0.1 0.23 11.1 0.1 1.3 1 0 0 1 1 1 0 NACHT domain ABC_tran PF00005.22 CBZ56005.1 - 0.16 12.3 0.1 0.74 10.1 0.0 1.9 2 0 0 2 2 2 0 ABC transporter AAA_24 PF13479.1 CBZ56005.1 - 0.17 11.4 0.5 0.39 10.2 0.0 1.7 2 0 0 2 2 2 0 AAA domain Prefoldin_2 PF01920.15 CBZ56008.1 - 3.9e-15 55.4 8.4 5.8e-15 54.9 5.8 1.3 1 0 0 1 1 1 1 Prefoldin subunit DUF4404 PF14357.1 CBZ56008.1 - 0.015 15.7 0.8 0.015 15.7 0.6 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) Nup54 PF13874.1 CBZ56008.1 - 0.022 14.4 0.9 0.022 14.4 0.6 2.2 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 PilJ PF13675.1 CBZ56008.1 - 0.056 13.7 3.2 4.9 7.4 2.2 2.1 1 1 0 1 1 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term DUF1664 PF07889.7 CBZ56008.1 - 0.26 11.0 7.9 4.6 7.0 1.0 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) GAS PF13851.1 CBZ56008.1 - 0.29 10.2 12.1 1.2 8.2 1.4 2.1 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding HR1 PF02185.11 CBZ56008.1 - 0.38 10.5 10.6 0.8 9.4 1.9 3.0 1 1 2 3 3 3 0 Hr1 repeat ATP-synt_B PF00430.13 CBZ56008.1 - 0.55 10.0 6.7 0.15 11.8 0.6 2.2 2 0 0 2 2 2 0 ATP synthase B/B' CF(0) IncA PF04156.9 CBZ56008.1 - 0.68 9.4 7.0 1.6 8.2 0.2 2.1 2 0 0 2 2 2 0 IncA protein Prefoldin_3 PF13758.1 CBZ56008.1 - 0.74 9.6 6.4 1.7 8.4 1.7 3.0 1 1 1 2 2 2 0 Prefoldin subunit DUF4164 PF13747.1 CBZ56008.1 - 0.95 9.6 9.7 1.2 9.2 1.4 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4164) DUF1319 PF07028.6 CBZ56008.1 - 1.2 9.3 7.3 4.3 7.5 0.8 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1319) Phage_GP20 PF06810.6 CBZ56008.1 - 1.3 8.4 9.5 1.3 8.4 1.1 2.2 2 0 0 2 2 2 0 Phage minor structural protein GP20 KxDL PF10241.4 CBZ56008.1 - 1.4 8.8 6.4 0.2 11.5 0.8 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein Prefoldin PF02996.12 CBZ56008.1 - 2.3 7.8 9.5 2.4e+02 1.3 6.6 2.9 1 1 0 1 1 1 0 Prefoldin subunit CDC37_N PF03234.9 CBZ56008.1 - 2.5 8.4 8.0 4.2 7.6 5.5 1.4 1 1 0 1 1 1 0 Cdc37 N terminal kinase binding DivIC PF04977.10 CBZ56008.1 - 3.4 7.2 6.0 7 6.2 0.3 2.3 2 0 0 2 2 2 0 Septum formation initiator DUF3166 PF11365.3 CBZ56008.1 - 3.5 8.1 8.4 4.7 7.7 0.3 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF3166) DUF2968 PF11180.3 CBZ56008.1 - 3.6 6.9 11.9 0.28 10.5 2.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2968) Syntaxin PF00804.20 CBZ56008.1 - 3.7 7.7 9.5 2.5 8.3 1.2 2.4 2 1 0 2 2 2 0 Syntaxin Sec2p PF06428.6 CBZ56008.1 - 5 7.0 8.8 6.6 6.6 0.4 2.2 2 0 0 2 2 2 0 GDP/GTP exchange factor Sec2p HrpB7 PF09486.5 CBZ56008.1 - 6.4 6.6 9.6 0.4 10.5 2.1 1.9 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) Mnd1 PF03962.10 CBZ56008.1 - 7.9 6.0 10.3 35 3.9 5.4 2.1 1 1 0 1 1 1 0 Mnd1 family DUF2981 PF11200.3 CBZ56009.1 - 1e-06 28.1 5.4 5e-06 25.8 0.8 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF2981) Tetraspannin PF00335.15 CBZ56009.1 - 0.049 12.9 11.4 0.07 12.3 7.9 1.2 1 0 0 1 1 1 0 Tetraspanin family Arteri_Gl PF00951.13 CBZ56009.1 - 1.7 8.1 6.9 2.4 7.7 4.8 1.2 1 0 0 1 1 1 0 Arterivirus GL envelope glycoprotein PrgI PF12666.2 CBZ56009.1 - 2.3 8.4 8.2 0.77 9.9 3.3 1.8 1 1 1 2 2 2 0 PrgI family protein KOW PF00467.24 CBZ56010.1 - 8.3e-08 31.6 4.0 8.3e-08 31.6 2.8 2.0 2 1 0 2 2 2 1 KOW motif Methyltrans_RNA PF04452.9 CBZ56010.1 - 0.014 14.5 0.6 0.018 14.1 0.4 1.2 1 0 0 1 1 1 0 RNA methyltransferase Glyoxalase PF00903.20 CBZ56011.1 - 1.1e-36 125.5 0.0 4.6e-18 65.4 0.1 2.1 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 CBZ56011.1 - 2.8e-26 92.2 0.7 4.1e-12 46.6 0.0 2.5 2 1 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_4 PF13669.1 CBZ56011.1 - 3.4e-12 46.3 0.0 9.3e-05 22.4 0.0 3.4 2 2 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.1 CBZ56011.1 - 0.0015 18.4 0.0 0.21 11.4 0.0 2.3 2 0 0 2 2 2 1 Glyoxalase-like domain DUF3081 PF11280.3 CBZ56011.1 - 0.0065 15.9 0.0 2.1 7.9 0.0 2.7 2 0 0 2 2 2 2 Protein of unknown function (DUF3081) Toxin_67 PF15545.1 CBZ56011.1 - 0.13 12.1 0.1 0.8 9.6 0.0 2.1 2 0 0 2 2 2 0 Putative toxin 67 CppA_N PF14506.1 CBZ56011.1 - 0.16 11.6 0.0 12 5.6 0.0 2.2 2 0 0 2 2 2 0 CppA N-terminal MFS_1 PF07690.11 CBZ56012.1 - 4.1e-09 35.6 32.3 1.3e-07 30.7 20.9 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily zf-RING_2 PF13639.1 CBZ56015.1 - 1.7e-11 43.7 8.1 2.9e-11 43.0 5.6 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 CBZ56015.1 - 3e-07 30.4 3.9 5.5e-07 29.5 2.7 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 CBZ56015.1 - 6.9e-07 28.8 6.2 1.1e-06 28.2 4.3 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 CBZ56015.1 - 1.5e-06 27.7 8.8 2.4e-06 27.0 6.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CBZ56015.1 - 7.4e-06 25.8 8.1 1.3e-05 25.1 5.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CBZ56015.1 - 1.8e-05 24.3 5.9 3e-05 23.5 4.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DUF1272 PF06906.6 CBZ56015.1 - 0.0019 18.0 2.4 0.0053 16.5 1.4 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1272) zf-Apc11 PF12861.2 CBZ56015.1 - 0.0069 16.1 2.7 0.014 15.2 1.9 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 CBZ56015.1 - 0.035 13.6 5.4 0.074 12.6 3.7 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Baculo_RING PF05883.6 CBZ56015.1 - 0.15 11.8 0.8 0.27 11.0 0.5 1.3 1 0 0 1 1 1 0 Baculovirus U-box/Ring-like domain FANCL_C PF11793.3 CBZ56015.1 - 0.44 10.5 5.6 1 9.3 3.8 1.6 1 1 0 1 1 1 0 FANCL C-terminal domain RINGv PF12906.2 CBZ56015.1 - 1.8 8.6 8.2 3.1 7.9 5.7 1.4 1 0 0 1 1 1 0 RING-variant domain ubiquitin PF00240.18 CBZ56016.1 - 8e-11 41.1 0.1 8.7e-07 28.2 0.0 2.4 2 0 0 2 2 2 2 Ubiquitin family Ubiquitin_2 PF14560.1 CBZ56016.1 - 0.037 14.2 0.4 0.67 10.2 0.1 2.5 2 1 0 2 2 2 0 Ubiquitin-like domain TPR_15 PF13429.1 CBZ56016.1 - 0.11 11.4 0.0 0.17 10.9 0.0 1.1 1 0 0 1 1 1 0 Tetratricopeptide repeat Peptidase_S8 PF00082.17 CBZ56017.1 - 4.3e-28 98.2 0.6 5.6e-28 97.8 0.4 1.1 1 0 0 1 1 1 1 Subtilase family HEPPP_synt_1 PF07307.6 CBZ56017.1 - 0.11 11.9 0.0 0.38 10.1 0.0 1.8 2 0 0 2 2 2 0 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1 Ribosomal_S4 PF00163.14 CBZ56018.1 - 6e-25 87.4 3.2 1.1e-24 86.6 2.2 1.4 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.20 CBZ56018.1 - 5.6e-13 48.1 0.8 5.6e-13 48.1 0.5 2.0 2 0 0 2 2 2 1 S4 domain HTH_31 PF13560.1 CBZ56019.1 - 6.5e-05 23.0 0.4 0.00012 22.2 0.0 1.7 2 1 0 2 2 2 1 Helix-turn-helix domain Nup54 PF13874.1 CBZ56020.1 - 2.9e-27 95.0 1.3 2.9e-27 95.0 0.9 2.8 3 0 0 3 3 3 1 Nucleoporin complex subunit 54 Nucleoporin_FG PF13634.1 CBZ56020.1 - 3.1e-05 24.1 12.8 6.1e-05 23.2 8.9 1.5 1 0 0 1 1 1 1 Nucleoporin FG repeat region Cluap1 PF10234.4 CBZ56020.1 - 0.21 10.7 3.8 1.2 8.3 0.4 2.4 2 0 0 2 2 2 0 Clusterin-associated protein-1 Calpain_inhib PF00748.14 CBZ56020.1 - 0.31 11.3 0.0 0.31 11.3 0.0 2.7 3 0 0 3 3 3 0 Calpain inhibitor Spc7 PF08317.6 CBZ56020.1 - 0.74 8.4 5.0 2 6.9 0.2 2.2 2 0 0 2 2 2 0 Spc7 kinetochore protein BLOC1_2 PF10046.4 CBZ56020.1 - 10 6.3 8.9 16 5.6 0.8 2.6 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Chorein_N PF12624.2 CBZ56021.1 - 0.0032 16.9 0.0 0.0065 15.9 0.0 1.4 1 0 0 1 1 1 1 N-terminal region of Chorein, a TM vesicle-mediated sorter DUF1162 PF06650.7 CBZ56021.1 - 0.013 14.7 0.0 0.12 11.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1162) PI3_PI4_kinase PF00454.22 CBZ56023.1 - 9e-40 136.6 0.0 3.1e-39 134.8 0.0 1.8 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.15 CBZ56023.1 - 9e-08 31.4 0.2 2e-07 30.3 0.1 1.5 1 0 0 1 1 1 1 FATC domain SNase PF00565.12 CBZ56025.1 - 2.3e-14 53.5 4.5 5.8e-06 26.5 0.3 3.4 2 1 0 2 2 2 2 Staphylococcal nuclease homologue CobT PF06213.7 CBZ56025.1 - 0.0067 15.5 0.3 0.016 14.3 0.0 1.7 2 0 0 2 2 2 1 Cobalamin biosynthesis protein CobT Histone PF00125.19 CBZ56027.1 - 1.9e-21 75.9 0.1 2.5e-21 75.5 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 CBZ56027.1 - 0.00012 22.1 0.0 0.00016 21.6 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Ribosomal_L37ae PF01780.14 CBZ56028.1 - 1.7e-39 133.5 9.4 2e-39 133.3 6.5 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family Zn_Tnp_IS1595 PF12760.2 CBZ56028.1 - 0.0053 16.5 2.9 0.0075 16.0 2.0 1.3 1 0 0 1 1 1 1 Transposase zinc-ribbon domain A2L_zn_ribbon PF08792.5 CBZ56028.1 - 0.0056 16.1 2.4 0.066 12.6 0.0 2.2 2 0 0 2 2 2 1 A2L zinc ribbon domain OrfB_Zn_ribbon PF07282.6 CBZ56028.1 - 0.04 13.5 0.7 0.059 13.0 0.5 1.3 1 0 0 1 1 1 0 Putative transposase DNA-binding domain zf-Di19 PF05605.7 CBZ56028.1 - 0.062 13.4 0.1 0.13 12.3 0.1 1.6 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.1 CBZ56028.1 - 0.064 13.6 1.2 3.8 8.0 0.1 2.9 3 0 0 3 3 3 0 C2H2-type zinc finger zf-H2C2_2 PF13465.1 CBZ56028.1 - 0.14 12.5 1.1 1.1 9.6 0.2 2.3 2 0 0 2 2 2 0 Zinc-finger double domain Elf1 PF05129.8 CBZ56028.1 - 0.15 11.7 2.0 0.27 10.9 1.4 1.4 1 1 0 1 1 1 0 Transcription elongation factor Elf1 like zf-BED PF02892.10 CBZ56028.1 - 0.4 10.4 3.2 2.9 7.7 0.2 2.3 1 1 1 2 2 2 0 BED zinc finger zf-C2H2 PF00096.21 CBZ56028.1 - 0.75 10.2 5.6 2.5 8.6 0.2 2.7 3 0 0 3 3 3 0 Zinc finger, C2H2 type Lar_restr_allev PF14354.1 CBZ56028.1 - 2 8.7 4.3 5.4 7.3 3.0 1.8 1 1 0 1 1 1 0 Restriction alleviation protein Lar Ribosomal_L44 PF00935.14 CBZ56028.1 - 6.8 6.7 8.5 15 5.6 4.9 2.2 1 1 1 2 2 2 0 Ribosomal protein L44 DUF2205 PF10224.4 CBZ56029.1 - 0.0014 18.1 1.7 0.0014 18.1 1.2 2.4 1 1 1 2 2 2 1 Predicted coiled-coil protein (DUF2205) CRIC_ras_sig PF10534.4 CBZ56029.1 - 0.002 18.1 0.2 0.0043 17.0 0.1 1.5 1 0 0 1 1 1 1 Connector enhancer of kinase suppressor of ras DUF755 PF05501.6 CBZ56029.1 - 0.03 14.3 2.3 0.03 14.3 1.6 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF755) DUF972 PF06156.8 CBZ56029.1 - 0.066 13.5 0.2 0.066 13.5 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF972) Nup54 PF13874.1 CBZ56029.1 - 0.25 10.9 6.1 0.69 9.5 4.2 1.8 1 1 0 1 1 1 0 Nucleoporin complex subunit 54 MRP-S31 PF15433.1 CBZ56029.1 - 1.9 7.8 7.4 2.8 7.2 4.8 1.5 1 1 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 UBA_4 PF14555.1 CBZ56031.1 - 7.9e-10 38.1 0.3 1.3e-09 37.3 0.2 1.4 1 0 0 1 1 1 1 UBA-like domain Thioredoxin_7 PF13899.1 CBZ56031.1 - 1.2e-07 31.6 0.1 1.2e-07 31.6 0.1 1.9 2 0 0 2 2 2 1 Thioredoxin-like EF1G PF00647.14 CBZ56032.1 - 8.6e-39 131.5 1.1 1.4e-38 130.8 0.1 1.9 2 0 0 2 2 2 1 Elongation factor 1 gamma, conserved domain GST_N_3 PF13417.1 CBZ56032.1 - 1.4e-09 38.0 0.0 2.9e-09 37.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 CBZ56032.1 - 2.6e-09 37.1 0.0 5.1e-09 36.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 CBZ56032.1 - 4.6e-09 36.6 0.0 1.2e-08 35.3 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 CBZ56032.1 - 1.2e-08 34.7 0.0 3.3e-08 33.4 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 CBZ56032.1 - 5.3e-07 29.4 0.0 1.8e-06 27.7 0.0 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 CBZ56032.1 - 9.1e-06 25.5 0.0 2.1e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain AMA-1 PF02430.10 CBZ56033.1 - 2.5e-57 194.8 4.2 3.2e-57 194.4 2.9 1.1 1 0 0 1 1 1 1 Apical membrane antigen 1 Aminotran_5 PF00266.14 CBZ56034.1 - 5e-46 157.1 0.0 2.9e-41 141.4 0.0 3.1 2 1 0 2 2 2 2 Aminotransferase class-V RLL PF10036.4 CBZ56035.1 - 1.8e-30 106.1 0.0 3.5e-30 105.2 0.0 1.6 1 1 0 1 1 1 1 Putative carnitine deficiency-associated protein CLAG PF03805.8 CBZ56036.1 - 7.7e-10 36.8 0.1 6.7e-05 20.4 0.0 3.1 3 0 0 3 3 3 3 Cytoadherence-linked asexual protein DUF454 PF04304.8 CBZ56036.1 - 0.0029 17.5 0.1 0.0029 17.5 0.1 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF454) COPIIcoated_ERV PF07970.7 CBZ56036.1 - 0.14 11.7 0.0 0.28 10.7 0.0 1.4 1 0 0 1 1 1 0 Endoplasmic reticulum vesicle transporter ACDC PF14733.1 CBZ56037.1 - 7.3e-10 38.8 0.8 0.00032 20.7 0.2 2.4 2 0 0 2 2 2 2 AP2-coincident C-terminal SPC22 PF04573.7 CBZ56038.1 - 6.1e-42 142.8 0.0 7e-42 142.6 0.0 1.0 1 0 0 1 1 1 1 Signal peptidase subunit UQ_con PF00179.21 CBZ56040.1 - 1.1e-38 131.8 0.0 1.6e-38 131.2 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme FAST_1 PF06743.10 CBZ56041.1 - 0.058 13.1 0.5 5.4 6.7 0.0 3.6 3 1 1 4 4 4 0 FAST kinase-like protein, subdomain 1 Peptidase_M41 PF01434.13 CBZ56042.1 - 5.6e-62 208.9 0.3 9.7e-62 208.2 0.2 1.3 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 CBZ56042.1 - 1.5e-41 141.6 0.0 4.5e-41 140.1 0.0 1.9 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 CBZ56042.1 - 4.4e-05 22.6 0.0 0.00012 21.2 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 CBZ56042.1 - 7.5e-05 22.4 0.1 0.00029 20.5 0.1 2.0 1 0 0 1 1 1 1 Part of AAA domain AAA_17 PF13207.1 CBZ56042.1 - 7.7e-05 23.4 0.1 0.00032 21.5 0.0 2.1 2 0 0 2 2 1 1 AAA domain AAA_22 PF13401.1 CBZ56042.1 - 8.6e-05 22.6 0.1 0.004 17.3 0.1 3.0 1 1 0 1 1 1 1 AAA domain TIP49 PF06068.8 CBZ56042.1 - 8.8e-05 21.3 0.3 0.00028 19.7 0.1 1.8 2 0 0 2 2 2 1 TIP49 C-terminus AAA_5 PF07728.9 CBZ56042.1 - 0.00066 19.4 0.1 0.0047 16.6 0.1 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.7 CBZ56042.1 - 0.0022 17.1 0.1 0.019 14.0 0.0 2.4 1 1 1 2 2 2 1 Zeta toxin AAA_16 PF13191.1 CBZ56042.1 - 0.0022 17.9 0.2 0.0022 17.9 0.1 4.4 4 1 0 4 4 4 1 AAA ATPase domain IstB_IS21 PF01695.12 CBZ56042.1 - 0.0042 16.5 1.7 0.0071 15.7 0.0 2.2 3 0 0 3 3 3 1 IstB-like ATP binding protein AAA_28 PF13521.1 CBZ56042.1 - 0.007 16.3 1.2 0.061 13.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 CBZ56042.1 - 0.011 15.3 0.3 0.24 11.0 0.0 2.6 2 0 0 2 2 2 0 NACHT domain AAA_33 PF13671.1 CBZ56042.1 - 0.016 15.0 0.0 0.061 13.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 CBZ56042.1 - 0.02 15.1 0.0 0.055 13.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 CBZ56042.1 - 0.026 13.7 0.2 0.056 12.6 0.1 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_25 PF13481.1 CBZ56042.1 - 0.058 12.7 2.0 0.56 9.5 0.1 2.7 2 1 1 3 3 3 0 AAA domain Sigma54_activat PF00158.21 CBZ56042.1 - 0.059 12.8 0.6 0.19 11.1 0.0 2.1 2 1 0 2 2 2 0 Sigma-54 interaction domain AAA_14 PF13173.1 CBZ56042.1 - 0.063 13.1 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain Ribosomal_L18e PF00828.14 CBZ56044.1 - 5.5e-23 81.7 0.1 8.9e-23 81.0 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 Archease PF01951.11 CBZ56045.1 - 6.9e-46 155.6 0.1 9e-46 155.2 0.0 1.2 1 0 0 1 1 1 1 Archease protein family (MTH1598/TM1083) GFO_IDH_MocA_C PF02894.12 CBZ56045.1 - 0.12 12.1 0.0 0.49 10.2 0.0 2.0 2 0 0 2 2 2 0 Oxidoreductase family, C-terminal alpha/beta domain THRAP3_BCLAF1 PF15440.1 CBZ56045.1 - 3.3 6.2 10.3 0.041 12.5 1.6 1.6 2 0 0 2 2 2 0 THRAP3/BCLAF1 family Ribosomal_S27e PF01667.12 CBZ56046.1 - 0.0065 15.9 2.5 0.65 9.5 0.1 2.4 2 0 0 2 2 2 2 Ribosomal protein S27 zf-RING_3 PF14369.1 CBZ56046.1 - 0.075 13.0 2.7 0.11 12.5 0.2 2.6 2 0 0 2 2 2 0 zinc-finger DZR PF12773.2 CBZ56046.1 - 0.63 9.9 4.6 8.9 6.2 3.2 2.7 1 1 1 2 2 2 0 Double zinc ribbon Mu-like_Com PF10122.4 CBZ56046.1 - 2.1 7.4 12.5 9.5 5.3 1.5 3.4 2 2 1 3 3 3 0 Mu-like prophage protein Com Spore_coat_CotO PF14153.1 CBZ56046.1 - 4.3 6.7 16.2 6.4 6.1 11.3 1.2 1 0 0 1 1 1 0 Spore coat protein CotO DUF35_N PF12172.3 CBZ56046.1 - 5.9 6.9 7.9 37 4.3 0.5 3.5 3 0 0 3 3 3 0 Rubredoxin-like zinc ribbon domain (DUF35_N) zf-Sec23_Sec24 PF04810.10 CBZ56046.1 - 7.5 6.2 11.9 15 5.2 3.4 3.4 3 1 0 3 3 3 0 Sec23/Sec24 zinc finger TFIIF_alpha PF05793.7 CBZ56046.1 - 9.4 4.4 23.5 12 4.0 16.3 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) EXS PF03124.9 CBZ56047.1 - 8.8e-33 113.7 2.0 1e-32 113.5 1.4 1.0 1 0 0 1 1 1 1 EXS family Gag_p10 PF02337.12 CBZ56048.1 - 0.046 13.4 18.6 69 3.2 0.1 7.5 7 0 0 7 7 7 0 Retroviral GAG p10 protein EF-hand_7 PF13499.1 CBZ56049.1 - 0.0061 16.6 0.1 0.1 12.7 0.0 2.4 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 CBZ56049.1 - 0.0096 15.1 0.0 0.034 13.4 0.1 2.0 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.1 CBZ56049.1 - 0.033 14.0 0.2 0.15 12.0 0.1 2.1 2 0 0 2 2 2 0 EF-hand domain EF-hand_5 PF13202.1 CBZ56049.1 - 0.18 11.1 0.4 0.49 9.8 0.3 1.8 1 0 0 1 1 1 0 EF hand Aminotran_1_2 PF00155.16 CBZ56050.1 - 2.9e-85 286.3 0.0 3.3e-85 286.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II MFS_1 PF07690.11 CBZ56051.1 - 4.3e-07 28.9 30.1 4.1e-05 22.4 2.4 2.4 2 1 0 2 2 2 2 Major Facilitator Superfamily PRRSV_2b PF07069.6 CBZ56051.1 - 9.8 6.5 9.3 11 6.3 0.0 3.6 3 0 0 3 3 3 0 Porcine reproductive and respiratory syndrome virus 2b Actin PF00022.14 CBZ56052.1 - 1e-125 419.3 0.0 1.3e-125 418.9 0.0 1.0 1 0 0 1 1 1 1 Actin RCC1 PF00415.13 CBZ56053.1 - 3.1e-116 379.5 63.2 3.4e-15 55.9 1.6 16.0 15 1 0 15 15 15 13 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 CBZ56053.1 - 1.6e-61 202.7 96.2 6.6e-08 31.9 1.6 14.7 14 1 0 14 14 14 14 Regulator of chromosome condensation (RCC1) repeat COX14 PF14880.1 CBZ56054.1 - 5.3e-17 61.1 1.0 6.6e-17 60.8 0.7 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c assembly Apc5 PF12862.2 CBZ56054.1 - 0.06 13.1 0.0 0.068 13.0 0.0 1.2 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 5 H_PPase PF03030.11 CBZ56055.1 - 4.6e-236 785.3 32.9 5.6e-236 785.0 22.8 1.0 1 0 0 1 1 1 1 Inorganic H+ pyrophosphatase UCH PF00443.24 CBZ56059.1 - 8.4e-05 21.8 0.0 0.18 10.9 0.1 2.2 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Calcyon PF06387.6 CBZ56061.1 - 0.38 10.1 8.0 9.9 5.4 0.0 4.4 5 0 0 5 5 5 0 D1 dopamine receptor-interacting protein (calcyon) DIM PF08194.7 CBZ56061.1 - 0.48 10.4 3.2 3.7 7.5 0.0 3.2 3 0 0 3 3 3 0 DIM protein cEGF PF12662.2 CBZ56061.1 - 0.75 9.4 0.0 0.75 9.4 0.0 9.8 12 0 0 12 12 12 0 Complement Clr-like EGF-like EB PF01683.13 CBZ56061.1 - 1.4 9.0 34.1 6.5 6.9 2.6 8.9 4 4 2 6 6 6 0 EB module WG_beta_rep PF14903.1 CBZ56062.1 - 2.5e-07 30.6 3.8 1.1e+02 3.2 0.0 8.5 9 0 0 9 9 9 1 WG containing repeat Cadherin-like PF12733.2 CBZ56063.1 - 0.0038 17.4 0.0 0.013 15.7 0.0 1.8 2 0 0 2 2 2 1 Cadherin-like beta sandwich domain Peptidase_S8 PF00082.17 CBZ56064.1 - 1.1e-53 182.2 3.9 1.5e-53 181.7 2.7 1.1 1 0 0 1 1 1 1 Subtilase family DUF3353 PF11833.3 CBZ56065.1 - 3.4 7.0 10.6 67 2.8 0.0 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF3353) SRR1 PF07985.7 CBZ56066.1 - 1.8e-12 47.0 0.0 3.1e-12 46.2 0.0 1.4 1 0 0 1 1 1 1 SRR1 Ribosomal_S21 PF01165.15 CBZ56067.1 - 0.025 13.9 0.0 0.068 12.6 0.0 1.7 1 0 0 1 1 1 0 Ribosomal protein S21 Vps5 PF09325.5 CBZ56067.1 - 0.13 11.4 0.6 1 8.5 0.0 2.1 2 0 0 2 2 2 0 Vps5 C terminal like SMN PF06003.7 CBZ56070.1 - 4.3 6.3 6.0 0.45 9.5 0.5 2.0 2 1 1 3 3 3 0 Survival motor neuron protein (SMN) PI-PLC-X PF00388.14 CBZ56071.1 - 1e-50 170.9 0.0 1.7e-50 170.2 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 CBZ56071.1 - 1e-29 102.8 0.0 2.2e-29 101.8 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain Mcp5_PH PF12814.2 CBZ56071.1 - 2.7e-20 72.4 0.0 4.1e-09 36.4 0.0 2.4 2 0 0 2 2 2 2 Meiotic cell cortex C-terminal pleckstrin homology C2 PF00168.25 CBZ56071.1 - 1.6e-08 34.2 0.0 3.6e-08 33.1 0.0 1.7 1 0 0 1 1 1 1 C2 domain EF-hand_like PF09279.6 CBZ56071.1 - 5e-08 32.8 0.2 4.6e-07 29.7 0.0 2.3 2 0 0 2 2 2 1 Phosphoinositide-specific phospholipase C, efhand-like EF-hand_10 PF14788.1 CBZ56071.1 - 3.8e-07 29.6 0.4 7.5e-07 28.7 0.3 1.5 1 0 0 1 1 1 1 EF hand EF-hand_1 PF00036.27 CBZ56071.1 - 7.8e-05 21.7 0.1 0.00022 20.3 0.0 1.8 1 0 0 1 1 1 1 EF hand EF-hand_8 PF13833.1 CBZ56071.1 - 0.00025 20.5 0.0 0.00047 19.7 0.0 1.5 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_7 PF13499.1 CBZ56071.1 - 0.00054 20.0 3.5 0.0084 16.2 0.1 2.3 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 CBZ56071.1 - 0.0013 18.3 0.1 0.0046 16.7 0.0 1.9 1 0 0 1 1 1 1 EF-hand domain MFS_1 PF07690.11 CBZ56072.1 - 4.8e-23 81.4 37.4 9.6e-23 80.4 24.8 2.3 1 1 0 1 1 1 1 Major Facilitator Superfamily Peptidase_M24 PF00557.19 CBZ56073.1 - 9.9e-43 146.1 0.0 1.3e-42 145.7 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-MYND PF01753.13 CBZ56073.1 - 5.9e-05 22.8 3.8 0.00019 21.2 2.7 1.9 1 0 0 1 1 1 1 MYND finger zf-FCS PF06467.9 CBZ56073.1 - 0.00028 20.4 5.3 0.0011 18.5 3.7 2.0 1 0 0 1 1 1 1 MYM-type Zinc finger with FCS sequence motif SNARE_assoc PF09335.6 CBZ56074.1 - 4.5e-09 36.5 3.0 4.5e-09 36.5 2.1 3.2 2 1 2 4 4 4 1 SNARE associated Golgi protein Ras PF00071.17 CBZ56075.1 - 1.2e-58 197.0 0.1 1.4e-58 196.8 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CBZ56075.1 - 1.9e-20 73.5 0.1 3.5e-20 72.6 0.0 1.5 2 0 0 2 2 1 1 Miro-like protein Arf PF00025.16 CBZ56075.1 - 1.4e-12 47.2 0.0 1.7e-12 46.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 CBZ56075.1 - 1.1e-07 31.7 0.0 1.8e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 CBZ56075.1 - 1.5e-07 31.0 0.0 6.5e-06 25.7 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 CBZ56075.1 - 4.4e-07 29.2 0.1 5.7e-07 28.9 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_22 PF13401.1 CBZ56075.1 - 0.00049 20.2 0.0 0.00081 19.5 0.0 1.7 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 CBZ56075.1 - 0.00088 18.4 0.4 0.002 17.3 0.1 1.7 2 1 0 2 2 2 1 Protein of unknown function, DUF258 Arch_ATPase PF01637.13 CBZ56075.1 - 0.001 18.8 0.4 0.0087 15.7 0.0 2.0 2 0 0 2 2 2 1 Archaeal ATPase AAA_16 PF13191.1 CBZ56075.1 - 0.0011 19.0 0.1 0.028 14.4 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain SRPRB PF09439.5 CBZ56075.1 - 0.0011 18.1 0.0 0.0016 17.7 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit ATP_bind_1 PF03029.12 CBZ56075.1 - 0.0024 17.4 0.2 0.1 12.1 0.0 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein Septin PF00735.13 CBZ56075.1 - 0.0041 16.1 0.1 0.0079 15.2 0.0 1.5 2 0 0 2 2 2 1 Septin AAA_24 PF13479.1 CBZ56075.1 - 0.0043 16.6 0.0 0.0066 16.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain MobB PF03205.9 CBZ56075.1 - 0.007 16.0 0.1 0.011 15.3 0.1 1.7 1 1 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_10 PF12846.2 CBZ56075.1 - 0.0075 15.7 0.0 0.01 15.3 0.0 1.4 1 1 0 1 1 1 1 AAA-like domain cobW PF02492.14 CBZ56075.1 - 0.013 14.9 0.1 0.042 13.3 0.0 1.8 1 1 1 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.4 CBZ56075.1 - 0.021 14.3 0.1 0.074 12.5 0.0 1.9 3 0 0 3 3 2 0 Ethanolamine utilisation - propanediol utilisation AAA_5 PF07728.9 CBZ56075.1 - 0.022 14.4 0.0 0.068 12.8 0.0 1.9 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) FeoB_N PF02421.13 CBZ56075.1 - 0.036 13.3 0.3 0.55 9.4 0.2 2.5 2 1 0 2 2 2 0 Ferrous iron transport protein B RNA_helicase PF00910.17 CBZ56075.1 - 0.045 13.9 0.0 0.19 11.9 0.0 2.0 2 0 0 2 2 2 0 RNA helicase NACHT PF05729.7 CBZ56075.1 - 0.055 13.1 0.0 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 NACHT domain NTPase_1 PF03266.10 CBZ56075.1 - 0.059 13.0 0.0 0.094 12.4 0.0 1.4 1 0 0 1 1 1 0 NTPase AAA PF00004.24 CBZ56075.1 - 0.059 13.5 0.0 0.28 11.3 0.0 2.0 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 CBZ56075.1 - 0.11 12.3 0.1 0.25 11.2 0.0 1.6 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.22 CBZ56075.1 - 0.13 12.6 0.0 0.29 11.4 0.0 1.6 2 0 0 2 2 2 0 ABC transporter Actin PF00022.14 CBZ56076.1 - 1.1e-52 178.8 0.0 3.9e-23 81.5 0.0 3.1 3 0 0 3 3 3 3 Actin zf-CCHC_3 PF13917.1 CBZ56078.1 - 2e-18 65.8 4.2 5.2e-18 64.4 2.9 1.8 1 0 0 1 1 1 1 Zinc knuckle Mito_carr PF00153.22 CBZ56079.1 - 6.8e-53 176.3 1.9 3.4e-16 58.7 0.2 5.1 2 2 1 3 3 3 3 Mitochondrial carrier protein Methyltransf_11 PF08241.7 CBZ56080.1 - 3.2e-06 27.5 0.3 0.00017 22.0 0.0 2.6 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 CBZ56080.1 - 5.1e-06 26.3 0.0 0.065 12.9 0.0 2.7 2 1 1 3 3 3 2 Methyltransferase domain Methyltransf_12 PF08242.7 CBZ56080.1 - 0.0058 17.0 0.1 0.054 13.9 0.1 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CBZ56080.1 - 0.024 15.2 0.8 6.1 7.4 0.0 2.5 1 1 1 2 2 2 0 Methyltransferase domain Methyltransf_9 PF08003.6 CBZ56080.1 - 0.11 11.1 0.0 0.16 10.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) LRR_4 PF12799.2 CBZ56081.1 - 1.1e-14 53.5 5.7 2.2e-05 23.9 0.1 4.7 3 1 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.1 CBZ56081.1 - 1.3e-10 41.1 0.6 0.00049 19.7 0.7 3.1 2 1 0 2 2 2 2 Leucine-rich repeat LRR_8 PF13855.1 CBZ56081.1 - 9.2e-10 38.1 6.0 3.4e-06 26.7 1.5 4.1 2 2 1 3 3 3 2 Leucine rich repeat LRR_1 PF00560.28 CBZ56081.1 - 0.0022 17.7 5.9 7.4 7.0 0.3 4.9 4 1 0 4 4 4 2 Leucine Rich Repeat LRR_7 PF13504.1 CBZ56081.1 - 0.0056 16.6 4.7 6.1 7.5 0.0 5.0 4 1 1 5 5 5 1 Leucine rich repeat LRR_6 PF13516.1 CBZ56081.1 - 0.0074 16.2 6.5 1 9.6 0.2 4.2 4 1 1 5 5 5 2 Leucine Rich repeat Nudc_N PF14050.1 CBZ56082.1 - 1.5e-19 69.6 0.0 4.3e-19 68.2 0.0 1.8 2 0 0 2 2 2 1 N-terminal conserved domain of Nudc. CS PF04969.11 CBZ56082.1 - 5.3e-10 39.7 0.1 8.1e-10 39.1 0.1 1.3 1 0 0 1 1 1 1 CS domain Vsr PF03852.10 CBZ56082.1 - 0.16 11.5 0.7 3.1 7.4 0.0 2.8 3 0 0 3 3 3 0 DNA mismatch endonuclease Vsr Prenylcys_lyase PF07156.9 CBZ56083.1 - 3.1e-15 55.9 0.0 4.8e-07 28.9 0.0 3.2 3 0 0 3 3 3 3 Prenylcysteine lyase NAD_binding_8 PF13450.1 CBZ56083.1 - 6.4e-06 26.0 0.3 2.8e-05 24.0 0.2 2.0 1 1 0 1 1 1 1 NAD(P)-binding Rossmann-like domain RCC1 PF00415.13 CBZ56084.1 - 3.3e-71 235.3 28.4 1.7e-14 53.7 0.1 9.7 8 2 0 8 8 8 8 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 CBZ56084.1 - 8.1e-37 124.0 51.2 2.9e-11 42.6 1.7 8.8 8 0 0 8 8 8 7 Regulator of chromosome condensation (RCC1) repeat CBM_X PF06204.6 CBZ56084.1 - 0.015 14.7 3.8 4.6 6.7 0.0 3.9 4 0 0 4 4 4 0 Putative carbohydrate binding domain Hira PF07569.6 CBZ56084.1 - 0.05 12.8 0.4 23 4.1 0.0 3.7 4 0 0 4 4 4 0 TUP1-like enhancer of split Methyltransf_18 PF12847.2 CBZ56085.1 - 1.1e-11 45.2 0.1 7.6e-10 39.3 0.0 2.4 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 CBZ56085.1 - 2.5e-08 33.6 0.0 1.9e-07 30.7 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 CBZ56085.1 - 8.1e-07 29.0 0.2 1.9e-06 27.8 0.1 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 CBZ56085.1 - 1.8e-05 25.1 0.0 5e-05 23.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CBZ56085.1 - 0.0001 22.0 0.0 0.00025 20.7 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 CBZ56085.1 - 0.00015 21.2 0.0 0.00034 20.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.7 CBZ56085.1 - 0.00017 21.9 0.0 0.00038 20.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CBZ56085.1 - 0.00027 21.2 0.0 0.00075 19.8 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 CBZ56085.1 - 0.0008 18.6 0.0 0.0013 17.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_9 PF08003.6 CBZ56085.1 - 0.002 16.8 0.0 0.0036 16.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Xylo_C PF12529.3 CBZ56085.1 - 0.067 12.5 0.1 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Xylosyltransferase C terminal Pox_MCEL PF03291.11 CBZ56085.1 - 0.07 11.9 0.0 0.1 11.4 0.0 1.2 1 0 0 1 1 1 0 mRNA capping enzyme Kinesin PF00225.18 CBZ56086.1 - 8.7e-92 307.3 0.0 1.3e-91 306.7 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain DUF87 PF01935.12 CBZ56086.1 - 0.99 9.1 4.9 0.77 9.5 0.3 2.2 2 0 0 2 2 2 0 Domain of unknown function DUF87 Exo_endo_phos PF03372.18 CBZ56087.1 - 2.3e-14 53.9 0.0 7.2e-14 52.3 0.0 1.8 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Pex2_Pex12 PF04757.9 CBZ56088.1 - 4.8e-20 71.9 0.1 4.8e-19 68.6 0.0 2.5 2 1 0 2 2 2 1 Pex2 / Pex12 amino terminal region Sybindin PF04099.7 CBZ56088.1 - 9.1e-20 70.8 0.0 1.6e-19 69.9 0.0 1.5 1 0 0 1 1 1 1 Sybindin-like family zf-C3HC4_3 PF13920.1 CBZ56088.1 - 6.6e-06 25.7 3.8 1.4e-05 24.6 2.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CBZ56088.1 - 4e-05 23.5 6.9 0.00012 22.0 4.8 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CBZ56088.1 - 0.006 16.3 6.9 0.006 16.3 4.8 2.2 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.20 CBZ56088.1 - 1.4 8.6 5.6 3.1 7.5 3.9 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) CytochromB561_N PF09786.4 CBZ56089.1 - 0.16 10.3 0.5 0.21 9.9 0.4 1.2 1 0 0 1 1 1 0 Cytochrome B561, N terminal TctB PF07331.6 CBZ56089.1 - 1.7 8.3 10.0 17 5.0 4.5 2.5 1 1 1 2 2 2 0 Tripartite tricarboxylate transporter TctB family LSM PF01423.17 CBZ56090.1 - 1.3e-20 72.7 0.1 1.5e-20 72.4 0.0 1.1 1 0 0 1 1 1 1 LSM domain DLIC PF05783.6 CBZ56091.1 - 8.8e-22 77.4 0.0 8.8e-22 77.4 0.0 4.3 2 2 0 3 3 3 1 Dynein light intermediate chain (DLIC) G-alpha PF00503.15 CBZ56091.1 - 0.001 17.8 0.0 0.0015 17.3 0.0 1.4 1 0 0 1 1 1 1 G-protein alpha subunit Methyltransf_11 PF08241.7 CBZ56092.1 - 1.2e-12 48.1 0.0 2.7e-12 47.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CBZ56092.1 - 4.6e-08 32.9 0.0 7.7e-08 32.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CBZ56092.1 - 3.3e-07 30.0 0.0 1.1e-06 28.2 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 CBZ56092.1 - 3.2e-06 27.5 0.0 7.5e-06 26.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CBZ56092.1 - 0.00055 20.2 0.0 0.0013 19.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 CBZ56092.1 - 0.002 17.2 0.0 0.0032 16.6 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.2 CBZ56092.1 - 0.023 15.2 0.0 0.051 14.1 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Glutaredoxin PF00462.19 CBZ56093.1 - 2.1e-10 40.3 0.0 4.1e-09 36.3 0.0 2.2 1 1 0 1 1 1 1 Glutaredoxin Tctex-1 PF03645.8 CBZ56095.1 - 2.1e-28 98.1 4.7 2.4e-28 97.9 3.3 1.0 1 0 0 1 1 1 1 Tctex-1 family Cpn60_TCP1 PF00118.19 CBZ56096.1 - 2.4e-125 418.9 10.7 2.8e-125 418.6 7.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family TAXi_C PF14541.1 CBZ56096.1 - 0.072 12.6 0.0 0.38 10.2 0.0 2.2 2 0 0 2 2 2 0 Xylanase inhibitor C-terminal ABC2_membrane PF01061.19 CBZ56097.1 - 1e-33 116.2 10.9 1.6e-33 115.6 7.6 1.3 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.22 CBZ56097.1 - 7.7e-16 58.6 0.0 2.2e-15 57.1 0.0 1.7 1 1 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.2 CBZ56097.1 - 7e-06 25.3 11.7 7e-06 25.3 8.1 1.7 2 0 0 2 2 2 1 ABC-2 family transporter protein AAA_29 PF13555.1 CBZ56097.1 - 0.00052 19.4 0.0 0.0011 18.4 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_25 PF13481.1 CBZ56097.1 - 0.00052 19.4 0.0 0.0078 15.6 0.0 2.6 3 0 0 3 3 2 1 AAA domain T2SE PF00437.15 CBZ56097.1 - 0.0016 17.4 0.0 0.0028 16.5 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_16 PF13191.1 CBZ56097.1 - 0.0021 18.0 0.9 0.0043 17.0 0.1 2.0 2 1 0 2 2 1 1 AAA ATPase domain DUF258 PF03193.11 CBZ56097.1 - 0.0026 16.9 0.0 0.0046 16.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_21 PF13304.1 CBZ56097.1 - 0.0027 17.7 0.1 0.016 15.1 0.0 2.2 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.1 CBZ56097.1 - 0.0029 17.7 0.0 0.0096 16.0 0.0 1.9 2 0 0 2 2 1 1 AAA domain AAA_23 PF13476.1 CBZ56097.1 - 0.0039 17.5 0.1 0.0065 16.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.1 CBZ56097.1 - 0.004 17.1 0.0 0.0072 16.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 CBZ56097.1 - 0.0068 17.2 0.0 0.015 16.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain cobW PF02492.14 CBZ56097.1 - 0.0098 15.3 0.1 0.016 14.6 0.0 1.3 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.1 CBZ56097.1 - 0.011 15.5 0.1 0.038 13.8 0.0 2.0 2 0 0 2 2 1 0 AAA domain FtsK_SpoIIIE PF01580.13 CBZ56097.1 - 0.02 14.3 0.3 0.059 12.8 0.0 1.8 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_19 PF13245.1 CBZ56097.1 - 0.021 14.5 0.1 0.076 12.7 0.1 1.9 1 0 0 1 1 1 0 Part of AAA domain NACHT PF05729.7 CBZ56097.1 - 0.022 14.4 0.0 0.059 13.0 0.0 1.7 1 0 0 1 1 1 0 NACHT domain AAA_10 PF12846.2 CBZ56097.1 - 0.022 14.1 0.0 0.043 13.2 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain Arch_ATPase PF01637.13 CBZ56097.1 - 0.034 13.8 0.0 0.054 13.1 0.0 1.2 1 0 0 1 1 1 0 Archaeal ATPase AAA_18 PF13238.1 CBZ56097.1 - 0.039 14.2 0.0 0.078 13.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.1 CBZ56097.1 - 0.049 13.1 0.0 0.091 12.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain UPF0079 PF02367.12 CBZ56097.1 - 0.071 12.7 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 MMR_HSR1 PF01926.18 CBZ56097.1 - 0.092 12.7 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase IstB_IS21 PF01695.12 CBZ56097.1 - 0.11 11.9 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein ABC_ATPase PF09818.4 CBZ56097.1 - 0.16 10.5 0.0 0.24 9.9 0.0 1.2 1 0 0 1 1 1 0 Predicted ATPase of the ABC class AAA_14 PF13173.1 CBZ56097.1 - 0.17 11.7 0.0 0.33 10.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain SRPRB PF09439.5 CBZ56097.1 - 0.2 10.8 0.0 0.35 10.0 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_24 PF13479.1 CBZ56097.1 - 0.29 10.6 0.1 0.52 9.8 0.1 1.3 1 0 0 1 1 1 0 AAA domain Miro PF08477.8 CBZ56097.1 - 0.34 11.4 0.0 0.61 10.6 0.0 1.4 1 0 0 1 1 1 0 Miro-like protein Rad17 PF03215.10 CBZ56097.1 - 0.53 8.9 0.0 0.75 8.4 0.0 1.1 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein FBPase PF00316.15 CBZ56098.1 - 5.3e-122 406.6 0.0 6.2e-122 406.4 0.0 1.0 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase ACOX PF01756.14 CBZ56099.1 - 5.3e-34 117.2 0.0 1.2e-33 116.0 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.1 CBZ56099.1 - 1.4e-12 47.9 0.0 2.7e-12 47.0 0.0 1.4 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal zf-RING_2 PF13639.1 CBZ56100.1 - 1e-09 38.0 3.0 2.8e-09 36.6 2.0 1.8 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 CBZ56100.1 - 2.7e-09 36.9 3.5 6.8e-09 35.6 2.5 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CBZ56100.1 - 1.9e-07 30.6 1.7 4e-07 29.5 1.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 CBZ56100.1 - 6.2e-06 26.2 2.2 1.6e-05 24.9 1.2 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 CBZ56100.1 - 2.5e-05 23.8 0.8 5.3e-05 22.8 0.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBZ56100.1 - 3.7e-05 23.3 2.3 7.7e-05 22.3 1.6 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 CBZ56100.1 - 0.0004 20.1 1.0 0.0009 19.0 0.7 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.1 CBZ56100.1 - 0.0019 18.0 3.4 0.0044 16.8 2.4 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 CBZ56100.1 - 0.0021 17.7 1.3 0.0059 16.3 0.9 1.8 1 0 0 1 1 1 1 RING-type zinc-finger FANCL_C PF11793.3 CBZ56100.1 - 0.0088 15.9 1.7 0.033 14.1 1.1 2.0 1 0 0 1 1 1 1 FANCL C-terminal domain RINGv PF12906.2 CBZ56100.1 - 0.36 10.9 2.4 1.2 9.1 1.4 2.1 1 1 1 2 2 2 0 RING-variant domain Peptidase_C6 PF00851.13 CBZ56100.1 - 1.7 7.2 2.4 2.6 6.5 1.7 1.2 1 0 0 1 1 1 0 Helper component proteinase Nop PF01798.13 CBZ56101.1 - 1.5e-51 173.6 0.1 4.2e-51 172.1 0.1 1.8 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 CBZ56101.1 - 9e-22 76.6 0.0 1.6e-21 75.8 0.0 1.4 1 0 0 1 1 1 1 NOSIC (NUC001) domain NOP5NT PF08156.8 CBZ56101.1 - 2.4e-13 50.0 0.0 8.6e-13 48.2 0.0 2.1 1 0 0 1 1 1 1 NOP5NT (NUC127) domain RR_TM4-6 PF06459.7 CBZ56101.1 - 8.4 6.2 15.8 14 5.4 11.0 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 PCNA_N PF00705.13 CBZ56102.1 - 9.9e-45 151.1 5.3 9.9e-45 151.1 3.7 1.6 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.10 CBZ56102.1 - 1e-29 103.0 0.0 2.3e-29 101.8 0.0 1.5 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, C-terminal domain Rad9 PF04139.8 CBZ56102.1 - 5e-07 29.1 0.2 6.8e-07 28.6 0.1 1.1 1 0 0 1 1 1 1 Rad9 DUF908 PF06012.7 CBZ56103.1 - 2.4 7.4 0.0 4.5 6.4 0.0 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) DUF1206 PF06724.6 CBZ56105.1 - 0.12 12.1 0.3 0.21 11.3 0.2 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1206) DUF3077 PF11275.3 CBZ56106.1 - 0.027 14.4 0.0 0.062 13.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3077) AAA PF00004.24 CBZ56107.1 - 2.4e-30 105.4 0.0 5.3e-30 104.3 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.12 CBZ56107.1 - 0.0014 18.0 0.0 0.0038 16.6 0.0 1.6 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_22 PF13401.1 CBZ56107.1 - 0.033 14.3 0.0 0.094 12.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain MobB PF03205.9 CBZ56107.1 - 0.65 9.7 0.0 1.5 8.5 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Ribul_P_3_epim PF00834.14 CBZ56108.1 - 2e-66 222.9 0.0 2.4e-66 222.7 0.0 1.0 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family PcrB PF01884.12 CBZ56108.1 - 0.0051 16.0 0.0 0.021 14.1 0.0 2.0 1 1 0 1 1 1 1 PcrB family Thioredoxin PF00085.15 CBZ56109.1 - 5.4e-12 45.3 0.0 1.8e-11 43.6 0.0 2.0 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_6 PF13848.1 CBZ56109.1 - 1.1e-06 28.5 0.0 0.00048 19.9 0.1 3.1 3 1 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_2 PF13098.1 CBZ56109.1 - 0.00011 22.3 0.5 0.008 16.3 0.0 3.4 3 1 0 3 3 3 1 Thioredoxin-like domain AhpC-TSA PF00578.16 CBZ56109.1 - 0.0035 17.0 0.1 1.6 8.4 0.0 2.4 2 0 0 2 2 2 2 AhpC/TSA family KaiB PF07689.7 CBZ56109.1 - 0.009 15.4 0.0 0.02 14.3 0.0 1.5 1 0 0 1 1 1 1 KaiB domain PAN_4 PF14295.1 CBZ56110.1 - 7.9e-20 70.3 18.1 6.3e-06 25.7 2.4 4.5 4 0 0 4 4 4 4 PAN domain PAN_1 PF00024.21 CBZ56110.1 - 4.4e-19 68.0 19.6 5.5e-05 22.8 3.2 4.6 4 0 0 4 4 4 4 PAN domain UAA PF08449.6 CBZ56111.1 - 8.8e-14 51.1 2.5 1.1e-13 50.7 0.0 2.0 2 0 0 2 2 2 1 UAA transporter family TPT PF03151.11 CBZ56111.1 - 0.075 12.6 14.7 0.46 10.1 4.4 3.7 3 1 0 3 3 3 0 Triose-phosphate Transporter family Ras PF00071.17 CBZ56112.1 - 3.8e-54 182.4 0.2 5.2e-54 181.9 0.2 1.2 1 0 0 1 1 1 1 Ras family Kelch_4 PF13418.1 CBZ56112.1 - 7.7e-30 102.4 0.9 6.1e-06 25.9 0.0 7.6 7 1 0 7 7 7 6 Galactose oxidase, central domain Kelch_3 PF13415.1 CBZ56112.1 - 2.4e-22 78.5 1.2 0.0034 17.5 0.0 9.6 9 0 0 9 9 9 4 Galactose oxidase, central domain Miro PF08477.8 CBZ56112.1 - 9.1e-18 64.8 0.0 7.6e-17 61.9 0.0 2.1 2 0 0 2 2 2 1 Miro-like protein Kelch_5 PF13854.1 CBZ56112.1 - 9.4e-18 63.7 2.2 0.0029 17.5 0.0 6.9 8 0 0 8 8 8 4 Kelch motif Kelch_2 PF07646.10 CBZ56112.1 - 1.4e-14 53.1 0.0 0.059 13.1 0.0 6.4 7 0 0 7 7 7 3 Kelch motif Kelch_6 PF13964.1 CBZ56112.1 - 1.6e-13 50.1 0.0 0.24 11.6 0.0 6.8 7 0 0 7 7 7 4 Kelch motif Arf PF00025.16 CBZ56112.1 - 3.7e-13 49.0 0.0 5.7e-13 48.4 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 CBZ56112.1 - 8.5e-08 31.6 0.1 1.2e-07 31.1 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Kelch_1 PF01344.20 CBZ56112.1 - 2.9e-07 29.9 0.0 0.6 9.7 0.0 5.2 5 1 0 5 5 5 2 Kelch motif MMR_HSR1 PF01926.18 CBZ56112.1 - 0.0014 18.5 0.0 0.0025 17.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 CBZ56112.1 - 0.0024 17.3 0.0 0.0073 15.7 0.0 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 CBZ56112.1 - 0.15 11.2 0.0 0.25 10.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 BBS2_N PF14781.1 CBZ56112.1 - 0.18 11.4 0.2 0.81 9.3 0.0 2.1 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, N-terminal Thymidylat_synt PF00303.14 CBZ56113.1 - 2.1e-109 364.7 0.0 4.7e-83 278.2 0.0 2.1 2 0 0 2 2 2 2 Thymidylate synthase DHFR_1 PF00186.14 CBZ56113.1 - 2.7e-27 95.3 0.0 2.8e-19 69.2 0.0 2.3 2 0 0 2 2 2 2 Dihydrofolate reductase AP2 PF00847.15 CBZ56114.1 - 0.016 15.3 0.1 0.016 15.3 0.1 1.8 2 0 0 2 2 2 0 AP2 domain TraV PF09676.5 CBZ56114.1 - 1.3 9.7 7.3 0.54 10.9 0.7 2.3 2 0 0 2 2 2 0 Type IV conjugative transfer system lipoprotein (TraV) Ctr PF04145.10 CBZ56115.1 - 2e-21 76.5 11.7 6.2e-20 71.7 8.1 2.1 1 1 0 1 1 1 1 Ctr copper transporter family Bactofilin PF04519.8 CBZ56117.1 - 0.19 11.7 12.3 5.9 6.9 0.0 5.4 4 1 2 6 6 6 0 Polymer-forming cytoskeletal EF-hand_1 PF00036.27 CBZ56118.1 - 1.1e-41 136.9 12.3 2.5e-10 38.8 0.7 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 CBZ56118.1 - 8.6e-37 125.1 6.3 3.3e-20 71.9 1.2 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 CBZ56118.1 - 1.3e-32 111.1 11.2 3e-16 58.7 0.5 4.1 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.1 CBZ56118.1 - 9e-31 102.9 6.4 1.2e-09 37.2 0.1 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 CBZ56118.1 - 1.9e-28 96.4 8.0 8.3e-07 28.0 0.1 4.3 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.1 CBZ56118.1 - 3.3e-15 55.7 0.1 3.5e-08 33.2 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.2 CBZ56118.1 - 1.2e-09 37.7 0.4 0.00022 20.9 0.1 2.2 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 CBZ56118.1 - 1.3e-08 34.8 0.0 0.0014 18.6 0.0 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EFhand_Ca_insen PF08726.5 CBZ56118.1 - 4.7e-06 26.4 1.3 6.2e-05 22.9 0.2 2.3 2 0 0 2 2 2 1 Ca2+ insensitive EF hand UPF0154 PF03672.8 CBZ56118.1 - 7.4e-06 25.4 0.1 0.19 11.3 0.0 3.1 3 0 0 3 3 3 2 Uncharacterised protein family (UPF0154) TerB PF05099.8 CBZ56118.1 - 0.00031 20.4 0.3 0.15 11.7 0.0 2.3 1 1 1 2 2 2 2 Tellurite resistance protein TerB Caleosin PF05042.8 CBZ56118.1 - 0.00048 19.7 0.2 0.037 13.5 0.1 2.6 1 1 0 1 1 1 1 Caleosin related protein DUF1103 PF06513.6 CBZ56118.1 - 0.0037 16.6 1.5 0.0043 16.4 1.0 1.2 1 0 0 1 1 1 1 Repeat of unknown function (DUF1103) RNA_pol_Rpb4 PF03874.11 CBZ56118.1 - 0.0059 16.5 0.4 1.7 8.6 0.1 2.5 2 0 0 2 2 2 1 RNA polymerase Rpb4 YqeY PF09424.5 CBZ56118.1 - 0.0097 15.7 0.3 0.11 12.3 0.1 2.0 1 1 1 2 2 2 1 Yqey-like protein EF-hand_like PF09279.6 CBZ56118.1 - 0.012 15.6 0.8 0.15 12.0 0.1 2.5 2 1 0 2 2 2 0 Phosphoinositide-specific phospholipase C, efhand-like MotA_activ PF09114.5 CBZ56118.1 - 0.03 14.0 0.2 6 6.7 0.0 2.3 2 0 0 2 2 2 0 Transcription factor MotA, activation domain Tenui_NCP PF04876.7 CBZ56118.1 - 0.031 13.8 0.1 0.37 10.3 0.0 2.0 1 1 1 2 2 2 0 Tenuivirus major non-capsid protein DUF853 PF05872.7 CBZ56118.1 - 0.059 11.7 0.1 1.6 6.9 0.0 2.0 1 1 0 2 2 2 0 Bacterial protein of unknown function (DUF853) LNS2 PF08235.8 CBZ56118.1 - 0.061 12.8 0.0 0.44 10.0 0.0 1.9 1 1 0 2 2 2 0 LNS2 (Lipin/Ned1/Smp2) DUF1880 PF08976.6 CBZ56118.1 - 0.083 13.0 0.0 1 9.4 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1880) SpoVIF PF14069.1 CBZ56118.1 - 0.1 12.3 0.4 1.6 8.4 0.1 2.4 2 1 0 2 2 2 0 Stage VI sporulation protein F Toprim_2 PF13155.1 CBZ56118.1 - 0.11 12.8 0.7 13 6.2 0.0 2.6 1 1 1 2 2 2 0 Toprim-like VCBS PF13517.1 CBZ56118.1 - 7.5 7.0 6.5 30 5.0 0.4 2.6 2 2 0 2 2 2 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Ribosomal_L35Ae PF01247.13 CBZ56119.1 - 1.9e-41 139.7 0.4 2.2e-41 139.5 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.13 CBZ56119.1 - 0.012 15.4 0.1 3.1 7.7 0.0 2.4 2 1 0 2 2 2 0 RimM N-terminal domain Pkinase PF00069.20 CBZ56120.1 - 1.8e-51 174.8 0.0 4.2e-24 85.1 0.0 3.2 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ56120.1 - 2e-16 59.8 0.1 1.4e-12 47.3 0.0 3.1 3 0 0 3 3 3 3 Protein tyrosine kinase Kinase-like PF14531.1 CBZ56120.1 - 0.026 13.4 0.0 0.041 12.8 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Seadorna_VP7 PF07387.6 CBZ56120.1 - 0.99 8.1 0.0 1.5 7.6 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 Thioredoxin PF00085.15 CBZ56121.1 - 8.1e-54 179.7 0.0 6.5e-30 102.8 0.0 2.3 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_8 PF13905.1 CBZ56121.1 - 4.7e-11 42.6 0.0 2e-05 24.5 0.0 2.9 2 1 0 2 2 2 2 Thioredoxin-like Thioredoxin_6 PF13848.1 CBZ56121.1 - 5.3e-11 42.6 0.0 3.2e-05 23.8 0.0 3.2 2 1 1 3 3 3 2 Thioredoxin-like domain Thioredoxin_7 PF13899.1 CBZ56121.1 - 3.9e-10 39.6 0.1 0.00052 19.9 0.0 2.6 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_2 PF13098.1 CBZ56121.1 - 1.2e-09 38.2 2.0 0.001 19.2 0.1 4.4 3 2 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_3 PF13192.1 CBZ56121.1 - 2e-06 27.5 0.0 0.06 13.1 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin domain AhpC-TSA PF00578.16 CBZ56121.1 - 3.4e-05 23.5 0.2 0.031 13.9 0.0 2.6 3 0 0 3 3 3 2 AhpC/TSA family Thioredoxin_9 PF14595.1 CBZ56121.1 - 7.3e-05 22.3 0.2 0.11 12.1 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin Redoxin PF08534.5 CBZ56121.1 - 0.00043 19.8 0.1 0.077 12.5 0.0 2.4 2 0 0 2 2 2 1 Redoxin Thioredoxin_4 PF13462.1 CBZ56121.1 - 0.00088 19.3 0.0 0.57 10.1 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin DDE_Tnp_1_2 PF13586.1 CBZ56121.1 - 0.16 12.1 0.0 8.5 6.6 0.0 2.5 2 0 0 2 2 2 0 Transposase DDE domain PIH1 PF08190.7 CBZ56123.1 - 7.7e-09 35.4 0.3 2.1e-08 34.0 0.0 1.8 2 1 0 2 2 2 1 pre-RNA processing PIH1/Nop17 Abhydrolase_5 PF12695.2 CBZ56124.1 - 0.00061 19.5 0.1 0.0034 17.1 0.0 2.2 3 0 0 3 3 3 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 CBZ56124.1 - 0.025 13.7 0.0 0.037 13.2 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 CBZ56124.1 - 0.04 13.8 0.7 0.11 12.3 0.2 2.0 2 1 0 2 2 2 0 Alpha/beta hydrolase family FSH1 PF03959.8 CBZ56124.1 - 0.1 12.0 0.0 0.31 10.4 0.0 1.8 2 0 0 2 2 2 0 Serine hydrolase (FSH1) Neur_chan_memb PF02932.11 CBZ56124.1 - 0.43 10.4 3.0 7.8 6.3 0.0 2.3 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region UPF0172 PF03665.8 CBZ56125.1 - 8.3e-32 110.2 0.1 4.1e-18 65.5 0.0 2.1 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0172) JAB PF01398.16 CBZ56125.1 - 0.017 14.8 0.0 1.5 8.5 0.0 2.3 2 0 0 2 2 2 0 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Flavodoxin_1 PF00258.20 CBZ56126.1 - 1.5e-18 67.1 0.2 2.5e-16 59.9 0.0 2.4 2 0 0 2 2 2 2 Flavodoxin FAD_binding_1 PF00667.15 CBZ56126.1 - 1.7e-09 37.4 0.6 6.5e-08 32.2 0.1 2.8 2 1 0 2 2 2 1 FAD binding domain NAD_binding_1 PF00175.16 CBZ56126.1 - 0.00013 22.5 0.0 0.0028 18.2 0.0 2.8 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain SRP54_N PF02881.14 CBZ56126.1 - 0.42 10.7 1.5 0.69 10.0 0.2 1.9 2 0 0 2 2 2 0 SRP54-type protein, helical bundle domain Rad10 PF03834.9 CBZ56127.1 - 7.5e-18 63.9 0.0 1.2e-17 63.2 0.0 1.3 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) HHH_5 PF14520.1 CBZ56127.1 - 1.1e-05 25.4 0.0 2e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Helix-hairpin-helix domain HHH PF00633.18 CBZ56127.1 - 0.00013 21.4 0.0 0.00028 20.4 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_2 PF12826.2 CBZ56127.1 - 0.0093 15.8 0.0 0.017 15.0 0.0 1.4 1 0 0 1 1 1 1 Helix-hairpin-helix motif Abhydrolase_5 PF12695.2 CBZ56129.1 - 1.4e-14 54.0 0.0 2.8e-14 53.1 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CBZ56129.1 - 2.7e-08 33.9 0.0 6.9e-06 26.1 0.0 2.4 1 1 1 2 2 2 2 Alpha/beta hydrolase family Peptidase_S15 PF02129.13 CBZ56129.1 - 4.1e-06 26.4 0.3 1.1e-05 25.0 0.0 1.8 3 0 0 3 3 3 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_1 PF00561.15 CBZ56129.1 - 3.8e-05 23.3 0.1 0.00085 18.9 0.0 2.2 1 1 1 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.8 CBZ56129.1 - 0.066 12.7 0.1 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold SOG2 PF10428.4 CBZ56129.1 - 4.4 5.8 9.0 5.8 5.4 6.2 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein RED_N PF07808.8 CBZ56130.1 - 1.2e-31 109.8 6.9 1.2e-31 109.8 4.8 2.7 2 1 1 3 3 3 1 RED-like protein N-terminal region RED_C PF07807.6 CBZ56130.1 - 9.8e-15 54.7 3.4 9.8e-15 54.7 2.4 3.5 4 0 0 4 4 4 1 RED-like protein C-terminal region SUI1 PF01253.17 CBZ56131.1 - 1.8e-28 98.1 0.8 2.4e-28 97.7 0.5 1.2 1 0 0 1 1 1 1 Translation initiation factor SUI1 Img2 PF05046.9 CBZ56131.1 - 0.026 14.7 0.2 0.036 14.2 0.2 1.3 1 0 0 1 1 1 0 Mitochondrial large subunit ribosomal protein (Img2) zf-DHHC PF01529.15 CBZ56132.1 - 1.2e-29 102.9 0.7 2.5e-29 101.8 0.5 1.5 1 0 0 1 1 1 1 DHHC palmitoyltransferase RecR PF02132.10 CBZ56132.1 - 1 8.8 4.8 2.3 7.7 3.3 1.5 1 0 0 1 1 1 0 RecR protein ELFV_dehydrog PF00208.16 CBZ56133.1 - 6.5e-47 160.1 0.0 1.1e-46 159.3 0.0 1.4 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.7 CBZ56133.1 - 3.7e-26 90.9 0.0 2.7e-20 71.5 0.0 2.1 2 0 0 2 2 2 2 Bacterial NAD-glutamate dehydrogenase KCNQC3-Ank-G_bd PF11956.3 CBZ56133.1 - 0.071 13.1 0.0 0.19 11.8 0.0 1.7 1 0 0 1 1 1 0 Ankyrin-G binding motif of KCNQ2-3 WD40 PF00400.27 CBZ56137.1 - 2.3e-23 81.1 14.8 1.7e-06 27.6 0.0 7.5 8 0 0 8 8 8 6 WD domain, G-beta repeat Pkinase PF00069.20 CBZ56138.1 - 9.3e-05 21.6 0.0 0.00036 19.7 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Kinase-like PF14531.1 CBZ56138.1 - 0.0031 16.5 0.1 0.0056 15.6 0.0 1.4 1 0 0 1 1 1 1 Kinase-like TPR_11 PF13414.1 CBZ56139.1 - 6.7e-15 54.4 13.1 1.5e-10 40.5 2.3 3.8 3 0 0 3 3 3 2 TPR repeat TPR_1 PF00515.23 CBZ56139.1 - 3.4e-12 45.4 11.7 5.9e-05 22.4 0.6 4.2 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 CBZ56139.1 - 6.2e-10 38.2 11.6 0.011 15.6 0.0 4.6 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_9 PF13371.1 CBZ56139.1 - 0.0022 17.8 9.6 0.19 11.6 2.4 3.7 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 CBZ56139.1 - 0.041 13.6 2.6 59 3.7 0.2 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF3568 PF12092.3 CBZ56139.1 - 0.12 12.0 0.3 1.2 8.8 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3568) TPR_7 PF13176.1 CBZ56139.1 - 0.12 12.1 5.9 0.73 9.7 0.1 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 CBZ56139.1 - 0.28 11.9 0.1 0.28 11.9 0.1 6.5 5 1 1 6 6 4 0 Tetratricopeptide repeat TPR_6 PF13174.1 CBZ56139.1 - 0.31 11.5 6.6 17 6.1 0.0 4.7 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_17 PF13431.1 CBZ56139.1 - 0.31 11.3 3.9 26 5.3 0.3 3.8 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_12 PF13424.1 CBZ56139.1 - 0.65 9.9 10.4 2.1 8.3 1.1 4.0 3 1 0 3 3 3 0 Tetratricopeptide repeat Glycoamylase PF10091.4 CBZ56140.1 - 0.18 10.8 0.0 0.39 9.7 0.0 1.4 1 0 0 1 1 1 0 Putative glucoamylase DUF4398 PF14346.1 CBZ56142.1 - 0.053 13.5 8.1 0.079 13.0 5.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4398) PPP4R2 PF09184.6 CBZ56142.1 - 0.087 12.3 5.6 0.1 12.1 3.9 1.0 1 0 0 1 1 1 0 PPP4R2 RR_TM4-6 PF06459.7 CBZ56142.1 - 0.92 9.3 7.5 1.1 9.0 5.2 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF3435 PF11917.3 CBZ56142.1 - 1.6 7.3 6.9 1.9 7.1 4.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3435) FemAB PF02388.11 CBZ56142.1 - 1.6 7.3 4.8 2.2 6.8 3.3 1.1 1 0 0 1 1 1 0 FemAB family ANAPC15 PF15243.1 CBZ56142.1 - 1.7 8.7 12.3 2.6 8.1 8.5 1.2 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 15 Zip PF02535.17 CBZ56142.1 - 1.8 7.5 6.6 2.7 6.9 4.6 1.5 1 0 0 1 1 1 0 ZIP Zinc transporter IncA PF04156.9 CBZ56142.1 - 2 7.9 5.5 3 7.3 3.8 1.3 1 0 0 1 1 1 0 IncA protein DUF4407 PF14362.1 CBZ56142.1 - 2.5 6.9 5.6 3.2 6.6 3.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) BTV_NS2 PF04514.7 CBZ56142.1 - 3.3 6.4 7.0 3.8 6.2 4.9 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 CRM1_C PF08767.6 CBZ56143.1 - 1.1e-103 346.5 5.2 1.1e-103 346.5 3.6 3.4 3 1 1 4 4 4 1 CRM1 C terminal Xpo1 PF08389.7 CBZ56143.1 - 2.9e-38 131.1 6.8 3.7e-38 130.7 1.4 3.5 4 0 0 4 4 4 1 Exportin 1-like protein IBN_N PF03810.14 CBZ56143.1 - 6.9e-10 38.7 0.0 2.3e-09 37.0 0.0 2.0 1 0 0 1 1 1 1 Importin-beta N-terminal domain TFCD_C PF12612.3 CBZ56143.1 - 0.014 14.8 0.4 0.37 10.1 0.0 3.5 4 0 0 4 4 4 0 Tubulin folding cofactor D C terminal DZR PF12773.2 CBZ56145.1 - 0.012 15.4 16.0 0.098 12.4 6.0 3.6 1 1 1 2 2 2 0 Double zinc ribbon RNA_pol_L PF01193.19 CBZ56146.1 - 1.3e-10 40.1 0.0 3.4e-10 38.8 0.0 1.6 1 1 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_A_bac PF01000.21 CBZ56146.1 - 6.9e-06 26.1 0.0 0.002 18.2 0.0 2.5 2 0 0 2 2 2 2 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L_2 PF13656.1 CBZ56146.1 - 0.18 11.2 0.0 0.36 10.3 0.0 1.4 1 0 0 1 1 1 0 RNA polymerase Rpb3/Rpb11 dimerisation domain TFIIA PF03153.8 CBZ56147.1 - 4.1 7.1 12.1 4.4 7.1 8.4 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit MFS_1 PF07690.11 CBZ56148.1 - 7.5e-11 41.3 15.0 7.5e-11 41.3 10.4 2.2 2 1 0 2 2 2 1 Major Facilitator Superfamily Proteasome PF00227.21 CBZ56149.1 - 7.7e-55 185.1 0.2 1.1e-54 184.6 0.1 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 CBZ56149.1 - 4.2e-13 48.3 0.0 7.9e-13 47.4 0.0 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature MIF4G_like_2 PF09090.6 CBZ56151.1 - 3.8e-10 39.4 1.3 5.5e-10 38.8 0.0 1.9 2 0 0 2 2 2 1 MIF4G like MIF4G_like PF09088.6 CBZ56151.1 - 1.5e-05 24.5 0.5 0.00011 21.7 0.3 2.1 1 1 1 2 2 2 1 MIF4G like Hist_deacetyl PF00850.14 CBZ56152.1 - 5.2e-73 246.0 0.1 8.5e-67 225.6 0.1 2.1 2 0 0 2 2 2 2 Histone deacetylase domain GST_N_3 PF13417.1 CBZ56153.1 - 1.7e-10 40.9 0.0 3.7e-10 39.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 CBZ56153.1 - 1.4e-07 31.8 0.0 2.6e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 CBZ56153.1 - 6.7e-06 26.0 0.0 1.1e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.19 CBZ56153.1 - 3.9e-05 23.5 0.1 6.9e-05 22.7 0.1 1.4 1 0 0 1 1 1 1 Glutaredoxin GST_C_2 PF13410.1 CBZ56153.1 - 0.028 14.2 0.0 0.067 13.0 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain YjeF_N PF03853.10 CBZ56154.1 - 2.7e-39 134.4 0.0 3.3e-39 134.2 0.0 1.1 1 0 0 1 1 1 1 YjeF-related protein N-terminus Mito_carr PF00153.22 CBZ56157.1 - 1.5e-37 127.1 6.6 4.3e-14 51.9 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein ATP-synt_C PF00137.16 CBZ56159.1 - 2.5e-12 46.4 8.7 4.4e-12 45.7 6.0 1.4 1 0 0 1 1 1 1 ATP synthase subunit C PUL PF08324.6 CBZ56160.1 - 0.011 14.5 1.0 1.3 7.7 0.1 2.3 1 1 1 2 2 2 0 PUL domain TMA7 PF09072.5 CBZ56161.1 - 5.8e-13 49.0 14.2 7.3e-13 48.7 9.8 1.2 1 0 0 1 1 1 1 Translation machinery associated TMA7 VKOR PF07884.9 CBZ56163.1 - 2.2e-23 82.6 11.4 2.9e-23 82.2 7.9 1.2 1 0 0 1 1 1 1 Vitamin K epoxide reductase family SPC25 PF06703.6 CBZ56163.1 - 0.41 10.1 5.2 0.83 9.2 2.5 2.1 1 1 1 2 2 2 0 Microsomal signal peptidase 25 kDa subunit (SPC25) Bax1-I PF01027.15 CBZ56164.1 - 2.2e-39 135.2 21.0 2.9e-39 134.7 14.6 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 CPDase PF07823.6 CBZ56165.1 - 1.3e-08 34.5 0.0 1.4e-07 31.1 0.0 2.1 1 1 0 1 1 1 1 Cyclic phosphodiesterase-like protein 2_5_RNA_ligase2 PF13563.1 CBZ56165.1 - 3.2e-05 23.7 0.2 9.4e-05 22.1 0.1 1.8 1 1 0 1 1 1 1 2'-5' RNA ligase superfamily Barstar PF01337.13 CBZ56166.1 - 0.073 12.9 0.0 0.17 11.7 0.0 1.6 1 0 0 1 1 1 0 Barstar (barnase inhibitor) Glyoxalase PF00903.20 CBZ56166.1 - 0.13 12.2 0.0 0.32 10.9 0.0 1.6 1 1 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Sec63 PF02889.11 CBZ56168.1 - 4.3e-118 394.1 0.0 2.4e-67 227.4 0.0 2.9 2 1 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.24 CBZ56168.1 - 1.2e-33 115.9 0.0 3.6e-23 81.9 0.0 3.6 3 1 0 3 3 3 2 DEAD/DEAH box helicase Helicase_C PF00271.26 CBZ56168.1 - 4.5e-16 58.4 0.0 4.2e-07 29.7 0.0 2.6 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.10 CBZ56168.1 - 7.5e-08 32.4 0.0 0.082 12.7 0.0 3.4 3 0 0 3 3 3 3 Type III restriction enzyme, res subunit AAA_19 PF13245.1 CBZ56168.1 - 0.00015 21.4 0.2 0.047 13.4 0.1 3.5 2 0 0 2 2 2 1 Part of AAA domain PhoH PF02562.11 CBZ56168.1 - 0.25 10.5 0.3 3.6 6.7 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein UvrD-helicase PF00580.16 CBZ56168.1 - 0.71 9.1 0.2 1.6 7.9 0.0 1.6 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain ABC_tran PF00005.22 CBZ56169.1 - 1e-30 106.8 0.0 4.7e-30 104.6 0.0 2.1 1 1 0 1 1 1 1 ABC transporter ABC_membrane PF00664.18 CBZ56169.1 - 3.1e-24 85.8 0.4 4.2e-24 85.4 0.3 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.14 CBZ56169.1 - 8.1e-07 28.4 0.0 0.00016 20.9 0.0 2.8 2 1 1 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.1 CBZ56169.1 - 0.00014 21.9 0.0 0.013 15.6 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA_21 PF13304.1 CBZ56169.1 - 0.00043 20.3 0.0 0.022 14.7 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 CBZ56169.1 - 0.00047 20.9 0.0 0.0032 18.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 CBZ56169.1 - 0.00057 19.9 6.8 0.0034 17.4 0.1 3.2 2 1 1 3 3 3 1 AAA ATPase domain DUF258 PF03193.11 CBZ56169.1 - 0.0035 16.5 0.0 0.0082 15.3 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Zeta_toxin PF06414.7 CBZ56169.1 - 0.0036 16.4 0.0 0.0087 15.1 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin AAA_33 PF13671.1 CBZ56169.1 - 0.0057 16.5 0.1 0.36 10.7 0.0 3.1 3 0 0 3 3 3 1 AAA domain ArgK PF03308.11 CBZ56169.1 - 0.0079 14.9 0.0 0.014 14.1 0.0 1.3 1 0 0 1 1 1 1 ArgK protein AAA_29 PF13555.1 CBZ56169.1 - 0.008 15.6 0.1 0.018 14.5 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_10 PF12846.2 CBZ56169.1 - 0.0093 15.4 0.1 0.1 11.9 0.0 2.2 2 0 0 2 2 2 1 AAA-like domain G-alpha PF00503.15 CBZ56169.1 - 0.011 14.4 0.5 0.016 13.8 0.3 1.3 1 1 0 1 1 1 0 G-protein alpha subunit Sigma54_activat PF00158.21 CBZ56169.1 - 0.024 14.1 0.0 0.053 12.9 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain APS_kinase PF01583.15 CBZ56169.1 - 0.025 14.2 0.0 0.052 13.2 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_25 PF13481.1 CBZ56169.1 - 0.035 13.4 0.0 0.13 11.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.17 CBZ56169.1 - 0.037 12.8 0.0 0.067 12.0 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain MobB PF03205.9 CBZ56169.1 - 0.043 13.5 0.0 0.38 10.4 0.0 2.2 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_23 PF13476.1 CBZ56169.1 - 0.052 13.8 0.6 0.19 12.0 0.0 2.2 3 0 0 3 3 1 0 AAA domain ABC_ATPase PF09818.4 CBZ56169.1 - 0.067 11.7 0.0 4.4 5.7 0.0 2.5 3 0 0 3 3 3 0 Predicted ATPase of the ABC class DUF87 PF01935.12 CBZ56169.1 - 0.08 12.7 0.0 0.18 11.5 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function DUF87 AAA_14 PF13173.1 CBZ56169.1 - 0.1 12.5 0.0 0.68 9.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 CBZ56169.1 - 0.12 12.6 0.2 0.51 10.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.18 CBZ56169.1 - 0.16 11.9 0.0 0.54 10.2 0.0 1.9 2 0 0 2 2 1 0 50S ribosome-binding GTPase Dynein_heavy PF03028.10 CBZ56170.1 - 5.3e-210 699.0 0.0 6.6e-208 692.1 0.0 2.3 2 0 0 2 2 2 1 Dynein heavy chain and region D6 of dynein motor DHC_N2 PF08393.8 CBZ56170.1 - 3.6e-126 420.9 0.9 3.6e-126 420.9 0.6 2.6 2 0 0 2 2 2 1 Dynein heavy chain, N-terminal region 2 AAA_6 PF12774.2 CBZ56170.1 - 2.1e-90 302.2 2.8 8.4e-90 300.3 0.1 3.4 4 0 0 4 4 4 1 Hydrolytic ATP binding site of dynein motor region D1 AAA_8 PF12780.2 CBZ56170.1 - 4.1e-67 225.9 0.1 1.3e-66 224.2 0.0 2.0 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 AAA_9 PF12781.2 CBZ56170.1 - 8.1e-53 178.5 0.7 1.5e-52 177.7 0.0 1.8 2 0 0 2 2 2 1 ATP-binding dynein motor region D5 AAA_7 PF12775.2 CBZ56170.1 - 1.6e-42 145.4 0.0 3e-42 144.5 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region D3 MT PF12777.2 CBZ56170.1 - 1.5e-33 116.0 11.0 4.2e-33 114.5 7.6 1.8 1 1 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_5 PF07728.9 CBZ56170.1 - 1.4e-22 79.9 0.4 2.8e-07 30.3 0.0 6.6 6 1 0 6 6 6 3 AAA domain (dynein-related subfamily) AAA PF00004.24 CBZ56170.1 - 2.1e-09 37.7 0.0 0.12 12.5 0.0 4.1 3 0 0 3 3 3 3 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 CBZ56170.1 - 6.3e-08 32.8 0.1 0.073 13.2 0.0 4.7 4 0 0 4 4 4 2 AAA domain T2SE PF00437.15 CBZ56170.1 - 1e-06 27.8 0.4 0.0094 14.8 0.0 3.2 3 0 0 3 3 3 2 Type II/IV secretion system protein AAA_17 PF13207.1 CBZ56170.1 - 4.4e-06 27.5 0.2 0.38 11.5 0.0 4.3 4 0 0 4 4 2 2 AAA domain AAA_19 PF13245.1 CBZ56170.1 - 1.6e-05 24.5 1.1 1.5 8.6 0.1 4.0 3 0 0 3 3 3 1 Part of AAA domain AAA_33 PF13671.1 CBZ56170.1 - 0.00011 22.0 0.1 0.52 10.1 0.0 4.6 4 0 0 4 4 4 1 AAA domain Zeta_toxin PF06414.7 CBZ56170.1 - 0.00013 21.1 1.7 1.5 7.8 0.0 4.2 4 0 0 4 4 4 1 Zeta toxin Sigma54_activat PF00158.21 CBZ56170.1 - 0.0002 20.8 0.1 3 7.3 0.0 3.5 3 0 0 3 3 3 2 Sigma-54 interaction domain DUF853 PF05872.7 CBZ56170.1 - 0.00021 19.7 4.6 1.5 7.0 0.2 3.4 3 0 0 3 3 3 3 Bacterial protein of unknown function (DUF853) AAA_18 PF13238.1 CBZ56170.1 - 0.00023 21.4 0.0 0.96 9.7 0.0 3.7 3 0 0 3 3 2 1 AAA domain RNA_helicase PF00910.17 CBZ56170.1 - 0.00064 19.8 0.0 2.4 8.4 0.0 3.8 3 0 0 3 3 3 1 RNA helicase ResIII PF04851.10 CBZ56170.1 - 0.0031 17.3 0.2 6 6.6 0.0 3.4 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit Mg_chelatase PF01078.16 CBZ56170.1 - 0.0086 15.2 0.4 0.29 10.2 0.0 3.0 4 0 0 4 4 2 1 Magnesium chelatase, subunit ChlI ABC_tran PF00005.22 CBZ56170.1 - 0.013 15.7 0.8 0.42 10.9 0.0 3.7 3 0 0 3 3 2 0 ABC transporter KaiC PF06745.8 CBZ56170.1 - 0.014 14.5 2.2 0.046 12.8 0.0 2.6 2 0 0 2 2 2 0 KaiC DEAD PF00270.24 CBZ56170.1 - 0.02 14.3 0.1 4.1 6.8 0.0 2.9 2 0 0 2 2 2 0 DEAD/DEAH box helicase SRP54 PF00448.17 CBZ56170.1 - 0.027 13.8 2.7 0.84 9.0 0.1 3.5 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain AAA_25 PF13481.1 CBZ56170.1 - 0.035 13.5 1.5 23 4.2 0.0 3.8 4 0 0 4 4 4 0 AAA domain FtsK_SpoIIIE PF01580.13 CBZ56170.1 - 0.036 13.5 1.0 3 7.2 0.0 3.3 4 0 0 4 4 3 0 FtsK/SpoIIIE family MobB PF03205.9 CBZ56170.1 - 0.11 12.2 0.2 5.5 6.6 0.0 3.3 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B Filament PF00038.16 CBZ56172.1 - 0.015 14.8 67.4 0.05 13.0 16.7 4.4 2 1 2 4 4 4 0 Intermediate filament protein OSTMP1 PF09777.4 CBZ56172.1 - 0.036 13.2 0.5 0.068 12.3 0.3 1.4 1 0 0 1 1 1 0 Osteopetrosis-associated transmembrane protein 1 precursor EST1 PF10374.4 CBZ56172.1 - 0.072 13.0 2.3 0.77 9.7 0.1 2.9 2 1 0 2 2 2 0 Telomerase activating protein Est1 Sterile PF03015.14 CBZ56172.1 - 0.093 13.0 0.0 0.28 11.4 0.0 1.8 1 0 0 1 1 1 0 Male sterility protein ABC_membrane_2 PF06472.10 CBZ56172.1 - 0.44 9.6 1.0 0.83 8.7 0.7 1.4 1 0 0 1 1 1 0 ABC transporter transmembrane region 2 Reo_sigmaC PF04582.7 CBZ56172.1 - 1.2 8.2 11.7 2.4 7.2 3.3 2.6 1 1 1 2 2 2 0 Reovirus sigma C capsid protein C2 PF00168.25 CBZ56173.1 - 1.7e-19 69.4 0.1 2.7e-19 68.7 0.1 1.3 1 0 0 1 1 1 1 C2 domain Cyclin_N PF00134.18 CBZ56174.1 - 4.7e-05 22.9 0.0 9e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain GGDN PF05165.7 CBZ56174.1 - 0.59 9.1 0.1 1 8.3 0.0 1.2 1 0 0 1 1 1 0 GGDN family Mito_carr PF00153.22 CBZ56176.1 - 3.1e-68 225.5 4.0 1.5e-24 85.5 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Hydrolase_like2 PF13246.1 CBZ56176.1 - 0.057 13.3 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 Putative hydrolase of sodium-potassium ATPase alpha subunit Pam16 PF03656.8 CBZ56177.1 - 1e-11 44.7 0.3 1.2e-11 44.4 0.2 1.1 1 0 0 1 1 1 1 Pam16 TP_methylase PF00590.15 CBZ56178.1 - 5e-20 72.1 0.0 1.6e-19 70.4 0.0 1.7 1 1 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases Ribosomal_L28e PF01778.12 CBZ56180.1 - 2.6e-27 95.5 1.6 2.6e-27 95.5 1.1 1.8 2 0 0 2 2 2 1 Ribosomal L28e protein family Mak16 PF04874.9 CBZ56180.1 - 3e-09 36.8 30.1 3e-09 36.8 20.8 3.9 5 1 0 5 5 5 1 Mak16 protein C-terminal region Ax_dynein_light PF10211.4 CBZ56181.1 - 5.7e-63 212.1 16.6 1.2e-62 211.1 11.5 1.5 1 1 0 1 1 1 1 Axonemal dynein light chain Allexi_40kDa PF05549.6 CBZ56181.1 - 0.0097 15.2 2.5 0.0097 15.2 1.7 2.3 2 1 1 3 3 3 1 Allexivirus 40kDa protein Syntaxin-6_N PF09177.6 CBZ56181.1 - 0.04 14.3 7.7 0.36 11.2 4.9 2.4 1 1 0 1 1 1 0 Syntaxin 6, N-terminal RasGAP_C PF03836.10 CBZ56181.1 - 0.047 13.3 11.8 0.048 13.3 5.4 2.4 1 1 0 2 2 2 0 RasGAP C-terminus DivIC PF04977.10 CBZ56181.1 - 0.092 12.2 10.3 0.56 9.7 2.6 3.2 3 0 0 3 3 3 0 Septum formation initiator Atg14 PF10186.4 CBZ56181.1 - 0.11 11.4 8.2 0.15 10.9 5.7 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Nsp1_C PF05064.8 CBZ56181.1 - 0.12 12.0 6.6 0.047 13.3 2.5 2.0 2 0 0 2 2 2 0 Nsp1-like C-terminal region Fib_alpha PF08702.5 CBZ56181.1 - 0.3 11.2 5.7 0.42 10.7 3.1 1.9 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family IncA PF04156.9 CBZ56181.1 - 0.39 10.2 12.8 0.23 11.0 7.4 1.7 1 1 1 2 2 2 0 IncA protein Enkurin PF13864.1 CBZ56181.1 - 0.45 10.7 16.8 2 8.6 3.0 2.8 2 1 1 3 3 3 0 Calmodulin-binding Tropomyosin_1 PF12718.2 CBZ56181.1 - 0.53 10.1 18.2 13 5.5 12.6 2.4 1 1 0 1 1 1 0 Tropomyosin like Nnf1 PF03980.9 CBZ56181.1 - 0.64 10.0 10.5 0.16 11.9 2.0 3.0 2 1 1 3 3 3 0 Nnf1 DUF1664 PF07889.7 CBZ56181.1 - 1.6 8.5 5.1 0.87 9.3 1.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Syntaxin PF00804.20 CBZ56181.1 - 5.6 7.1 10.1 39 4.4 7.0 2.3 1 1 0 1 1 1 0 Syntaxin GAS PF13851.1 CBZ56181.1 - 5.8 6.0 18.0 0.32 10.1 6.6 2.2 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding PH PF00169.24 CBZ56182.1 - 5.1e-06 26.6 1.8 1.1e-05 25.5 1.2 1.7 1 1 0 1 1 1 1 PH domain LRR_4 PF12799.2 CBZ56183.1 - 5.4e-14 51.4 5.3 3.7e-08 32.8 0.5 4.1 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CBZ56183.1 - 1.5e-09 37.4 2.1 1.5e-09 37.4 1.5 2.3 3 0 0 3 3 3 1 Leucine rich repeat LRR_1 PF00560.28 CBZ56183.1 - 2.4e-05 23.7 3.9 1.1 9.5 0.0 4.7 4 0 0 4 4 4 1 Leucine Rich Repeat LRR_9 PF14580.1 CBZ56183.1 - 0.00015 21.4 0.1 0.00022 20.8 0.0 1.3 1 0 0 1 1 1 1 Leucine-rich repeat LRR_7 PF13504.1 CBZ56183.1 - 0.00034 20.3 4.0 11 6.6 0.0 4.6 4 0 0 4 4 4 2 Leucine rich repeat LRR_6 PF13516.1 CBZ56183.1 - 0.0011 18.8 5.3 1.2 9.3 0.0 4.7 5 0 0 5 5 5 1 Leucine Rich repeat TPR_MLP1_2 PF07926.7 CBZ56184.1 - 0.0098 15.6 1.0 0.12 12.1 0.7 2.7 2 1 0 2 2 2 1 TPR/MLP1/MLP2-like protein Baculo_PEP_C PF04513.7 CBZ56184.1 - 0.026 14.3 8.7 3.9 7.2 0.6 3.6 1 1 3 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Laminin_II PF06009.7 CBZ56184.1 - 0.029 14.1 1.1 0.11 12.2 0.4 2.2 1 1 1 2 2 2 0 Laminin Domain II DUF4407 PF14362.1 CBZ56184.1 - 0.04 12.8 2.1 0.25 10.2 1.5 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) INCENP_N PF12178.3 CBZ56184.1 - 0.042 13.3 0.5 0.73 9.4 0.0 3.1 4 0 0 4 4 4 0 Chromosome passenger complex (CPC) protein INCENP N terminal DUF4363 PF14276.1 CBZ56184.1 - 0.11 12.1 0.2 2.8 7.6 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4363) Apolipoprotein PF01442.13 CBZ56184.1 - 0.26 10.7 16.2 0.015 14.8 4.9 2.7 2 1 1 3 3 3 0 Apolipoprotein A1/A4/E domain DUF3573 PF12097.3 CBZ56184.1 - 0.54 8.8 1.8 3.2 6.2 0.1 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF3573) BLOC1_2 PF10046.4 CBZ56184.1 - 0.62 10.2 6.0 5.6 7.1 0.1 3.7 2 1 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 IncA PF04156.9 CBZ56184.1 - 4.3 6.8 7.9 1.1e+02 2.2 5.3 2.7 1 1 1 2 2 2 0 IncA protein Sad1_UNC PF07738.8 CBZ56185.1 - 7.6e-24 84.0 0.0 2.5e-11 43.4 0.0 2.4 2 0 0 2 2 2 2 Sad1 / UNC-like C-terminal Spore_III_AB PF09548.5 CBZ56185.1 - 0.027 14.2 1.0 0.061 13.0 0.7 1.5 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) Prominin PF05478.6 CBZ56185.1 - 0.092 10.2 0.0 0.15 9.5 0.0 1.2 1 0 0 1 1 1 0 Prominin NOA36 PF06524.7 CBZ56185.1 - 0.84 8.8 10.9 1.4 8.1 7.5 1.2 1 0 0 1 1 1 0 NOA36 protein OmpH PF03938.9 CBZ56185.1 - 2.1 8.2 13.6 0.19 11.6 5.0 2.1 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) CENP-B_dimeris PF09026.5 CBZ56185.1 - 3.7 7.8 17.2 8.7 6.6 11.9 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain TRAP_alpha PF03896.11 CBZ56185.1 - 4.2 6.2 6.5 7.4 5.4 4.5 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit TFIIS_C PF01096.13 CBZ56188.1 - 4.8e-15 54.9 2.3 4.8e-15 54.9 1.6 3.1 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) Zn-ribbon_8 PF09723.5 CBZ56188.1 - 0.026 14.4 8.7 1.1 9.3 0.0 4.3 4 0 0 4 4 4 0 Zinc ribbon domain DNA_RNApol_7kD PF03604.8 CBZ56188.1 - 0.034 13.6 0.0 0.034 13.6 0.0 4.1 4 0 0 4 4 4 0 DNA directed RNA polymerase, 7 kDa subunit zf-ribbon_3 PF13248.1 CBZ56188.1 - 0.049 12.8 6.9 0.35 10.1 0.1 4.0 3 1 0 3 3 3 0 zinc-ribbon domain Baculo_LEF5_C PF11792.3 CBZ56188.1 - 0.51 9.7 6.8 0.32 10.4 2.5 2.4 2 0 0 2 2 2 0 Baculoviridae late expression factor 5 C-terminal domain DDRGK PF09756.4 CBZ56193.1 - 8.1e-46 155.8 24.3 2e-45 154.5 16.8 1.6 1 1 0 1 1 1 1 DDRGK domain DUF1777 PF08648.7 CBZ56193.1 - 0.19 11.4 21.8 0.31 10.7 15.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) EF-hand_1 PF00036.27 CBZ56194.1 - 3.5e-30 100.9 7.8 2.4e-09 35.8 0.0 4.3 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 CBZ56194.1 - 1.7e-29 101.7 9.7 1.2e-14 54.1 1.3 2.5 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.1 CBZ56194.1 - 2e-24 83.2 7.7 3.1e-09 35.9 0.0 4.5 4 1 1 5 5 5 4 EF-hand domain EF-hand_8 PF13833.1 CBZ56194.1 - 2e-24 84.9 10.4 3.9e-11 42.3 0.3 3.6 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.1 CBZ56194.1 - 8.9e-20 69.0 12.1 1.6e-06 27.1 0.0 4.5 4 1 0 4 4 4 3 EF hand EF-hand_9 PF14658.1 CBZ56194.1 - 4.6e-11 42.4 0.1 2e-07 30.7 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.2 CBZ56194.1 - 4.8e-06 26.2 1.9 0.04 13.6 0.1 3.2 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 CBZ56194.1 - 0.0027 17.7 0.0 2 8.4 0.0 2.1 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region Caleosin PF05042.8 CBZ56194.1 - 0.0044 16.6 0.0 0.11 11.9 0.0 2.3 2 1 0 2 2 2 1 Caleosin related protein TerB PF05099.8 CBZ56194.1 - 0.0089 15.7 0.1 2.9 7.6 0.0 3.0 2 1 0 2 2 2 1 Tellurite resistance protein TerB DUF3008 PF11450.3 CBZ56194.1 - 0.014 15.5 1.1 0.025 14.7 0.1 1.9 2 0 0 2 2 2 0 Protein of unknwon function (DUF3008) Toprim_2 PF13155.1 CBZ56194.1 - 0.015 15.5 0.1 0.91 9.8 0.0 2.3 1 1 1 2 2 2 0 Toprim-like IF2_N PF04760.10 CBZ56194.1 - 0.059 13.0 1.6 13 5.4 0.1 3.1 3 0 0 3 3 3 0 Translation initiation factor IF-2, N-terminal region Acetyltransf_11 PF13720.1 CBZ56194.1 - 0.082 13.1 0.0 1 9.6 0.0 2.3 1 1 2 3 3 3 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 DUF1257 PF06868.6 CBZ56194.1 - 0.094 12.6 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1257) Peptidase_M24 PF00557.19 CBZ56194.1 - 0.13 11.7 0.0 1.1 8.7 0.0 2.0 2 0 0 2 2 2 0 Metallopeptidase family M24 Cript PF10235.4 CBZ56195.1 - 4.5e-16 58.9 6.8 6.6e-16 58.4 4.7 1.3 1 1 0 1 1 1 1 Microtubule-associated protein CRIPT Peptidase_C74 PF12387.3 CBZ56195.1 - 0.0066 15.6 2.1 0.0069 15.5 1.4 1.1 1 0 0 1 1 1 1 Pestivirus NS2 peptidase DZR PF12773.2 CBZ56195.1 - 0.0082 15.9 7.3 0.031 14.0 5.2 1.8 1 1 1 2 2 2 2 Double zinc ribbon DiS_P_DiS PF06750.8 CBZ56195.1 - 0.039 13.7 5.1 0.096 12.4 3.6 1.7 1 1 0 1 1 1 0 Bacterial Peptidase A24 N-terminal domain DUF2039 PF10217.4 CBZ56195.1 - 0.04 13.9 5.5 0.057 13.4 3.8 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2039) zf-C3HC4_3 PF13920.1 CBZ56195.1 - 0.52 10.0 9.4 3.8 7.2 4.1 2.1 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zinc_ribbon_2 PF13240.1 CBZ56195.1 - 0.72 9.4 0.1 0.72 9.4 0.1 2.7 2 1 1 3 3 3 0 zinc-ribbon domain Sar8_2 PF03058.9 CBZ56195.1 - 2.8 8.3 6.1 3.9 7.8 4.2 1.4 1 1 0 1 1 1 0 Sar8.2 family zf-C3HC4_2 PF13923.1 CBZ56195.1 - 2.9 7.9 11.1 6.8 6.8 7.7 1.6 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Abhydrolase_3 PF07859.8 CBZ56196.1 - 1.5e-32 112.9 0.0 1.2e-27 96.8 0.0 2.5 2 1 0 3 3 3 2 alpha/beta hydrolase fold DUF2424 PF10340.4 CBZ56196.1 - 7.3e-10 38.0 0.0 1.1e-09 37.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 CBZ56196.1 - 4.9e-09 36.0 0.0 8.5e-09 35.3 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family RabGAP-TBC PF00566.13 CBZ56197.1 - 1.5e-19 70.3 0.6 3.7e-19 69.0 0.4 1.7 1 1 0 1 1 1 1 Rab-GTPase-TBC domain Pkinase PF00069.20 CBZ56197.1 - 7.2e-12 45.0 0.0 1e-09 37.9 0.0 3.0 3 1 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ56197.1 - 7.1e-05 21.9 0.0 0.00014 21.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Rhodanese PF00581.15 CBZ56197.1 - 0.0036 17.6 0.0 4.6 7.6 0.0 2.7 2 0 0 2 2 2 2 Rhodanese-like domain Pmp3 PF01679.12 CBZ56197.1 - 0.049 13.3 0.5 0.099 12.3 0.4 1.4 1 0 0 1 1 1 0 Proteolipid membrane potential modulator DUF4616 PF15394.1 CBZ56200.1 - 6.9 5.5 15.2 1.1 8.1 5.9 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4616) Ribosomal_L16 PF00252.13 CBZ56201.1 - 0.074 12.8 0.7 0.2 11.3 0.5 1.7 1 0 0 1 1 1 0 Ribosomal protein L16p/L10e Indigoidine_A PF04227.7 CBZ56201.1 - 0.082 12.1 3.4 0.055 12.6 0.4 2.0 2 1 0 3 3 3 0 Indigoidine synthase A like protein AAA_13 PF13166.1 CBZ56201.1 - 0.23 9.8 35.1 0.15 10.4 16.9 2.1 1 1 0 2 2 2 0 AAA domain TBPIP PF07106.8 CBZ56201.1 - 0.49 9.9 43.1 0.05 13.1 7.4 3.5 1 1 1 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) IL3 PF02059.10 CBZ56201.1 - 2.1 8.3 12.4 0.13 12.2 2.5 3.1 3 1 1 4 4 4 0 Interleukin-3 HOOK PF05622.7 CBZ56201.1 - 3.7 5.2 47.8 4.8 4.8 33.1 1.0 1 0 0 1 1 1 0 HOOK protein FlaC_arch PF05377.6 CBZ56201.1 - 5.4 6.9 17.6 11 6.0 0.1 4.8 4 1 1 5 5 5 0 Flagella accessory protein C (FlaC) Baculo_PEP_C PF04513.7 CBZ56201.1 - 6.4 6.5 16.2 5.4 6.8 3.8 3.7 2 1 2 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Reo_sigmaC PF04582.7 CBZ56201.1 - 9.5 5.2 8.4 27 3.7 0.1 2.9 1 1 1 3 3 3 0 Reovirus sigma C capsid protein Ribosomal_L30 PF00327.15 CBZ56202.1 - 0.00084 18.8 0.1 0.0077 15.8 0.0 2.5 1 1 1 2 2 2 1 Ribosomal protein L30p/L7e Yip1 PF04893.12 CBZ56203.1 - 1.1e-14 54.2 10.7 1.8e-14 53.6 7.4 1.4 1 0 0 1 1 1 1 Yip1 domain DUF2964 PF11177.3 CBZ56203.1 - 0.025 14.5 0.3 0.052 13.4 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2964) tRNA_U5-meth_tr PF05958.6 CBZ56204.1 - 3.8e-09 35.6 0.0 1.1e-08 34.1 0.0 1.7 2 0 0 2 2 2 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_26 PF13659.1 CBZ56204.1 - 2.4e-08 34.0 0.1 6.4e-08 32.6 0.1 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CBZ56204.1 - 3.1e-06 26.8 0.1 1.2e-05 24.8 0.1 1.8 1 1 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.13 CBZ56204.1 - 7.2e-05 22.4 0.0 0.00014 21.5 0.0 1.4 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_18 PF12847.2 CBZ56204.1 - 0.00013 22.4 0.2 0.0049 17.4 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 CBZ56204.1 - 0.088 12.1 0.1 11 5.3 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase small domain Met_10 PF02475.11 CBZ56204.1 - 0.16 11.5 0.0 0.29 10.7 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein PCMT PF01135.14 CBZ56204.1 - 0.17 11.4 0.1 1.4 8.3 0.0 2.0 1 1 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_15 PF09445.5 CBZ56204.1 - 0.28 10.7 0.0 1.6 8.2 0.0 2.1 2 0 0 2 2 2 0 RNA cap guanine-N2 methyltransferase PPR_2 PF13041.1 CBZ56205.1 - 6e-53 176.6 0.0 3.3e-12 46.1 0.0 9.3 7 2 3 10 10 10 9 PPR repeat family PPR_1 PF12854.2 CBZ56205.1 - 4.7e-39 131.5 0.2 5.1e-05 22.6 0.0 10.1 10 0 0 10 10 10 7 PPR repeat PPR_3 PF13812.1 CBZ56205.1 - 1.1e-38 128.2 11.0 0.00024 21.1 0.0 12.8 13 0 0 13 13 13 7 Pentatricopeptide repeat domain PPR PF01535.15 CBZ56205.1 - 1.8e-35 118.4 4.9 3.5e-05 23.4 0.0 12.2 13 1 0 13 13 13 7 PPR repeat DEAD PF00270.24 CBZ56206.1 - 4e-41 140.3 0.5 8.3e-41 139.2 0.1 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CBZ56206.1 - 2.5e-27 94.5 0.2 1.1e-26 92.4 0.1 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_19 PF13245.1 CBZ56206.1 - 7.1e-05 22.4 0.1 0.00017 21.2 0.1 1.7 1 0 0 1 1 1 1 Part of AAA domain ResIII PF04851.10 CBZ56206.1 - 0.00015 21.6 0.1 0.00062 19.6 0.0 2.0 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_RecD PF05127.9 CBZ56206.1 - 0.00048 19.8 0.0 0.0017 18.0 0.0 1.8 2 0 0 2 2 2 1 Helicase tRNA-synt_1b PF00579.20 CBZ56206.1 - 0.00053 19.2 0.0 0.0011 18.1 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) AAA_30 PF13604.1 CBZ56206.1 - 0.00077 19.0 0.0 0.0026 17.3 0.0 1.7 1 1 0 1 1 1 1 AAA domain CMS1 PF14617.1 CBZ56206.1 - 0.002 17.2 0.2 0.0062 15.6 0.0 1.8 2 0 0 2 2 2 1 U3-containing 90S pre-ribosomal complex subunit UvrD-helicase PF00580.16 CBZ56206.1 - 0.055 12.7 0.0 0.17 11.1 0.0 1.5 1 1 0 1 1 1 0 UvrD/REP helicase N-terminal domain zf-UBP PF02148.14 CBZ56207.1 - 8.8e-16 57.7 4.7 8.8e-16 57.7 3.3 1.7 2 0 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein DUF2183 PF09949.4 CBZ56208.1 - 2.4e-05 24.1 0.0 6.3e-05 22.8 0.0 1.7 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2183) Herpes_LMP2 PF07415.6 CBZ56209.1 - 2.2 6.7 2.9 5.3 5.5 2.0 1.6 1 0 0 1 1 1 0 Gammaherpesvirus latent membrane protein (LMP2) protein Ribosomal_L29 PF00831.18 CBZ56210.1 - 1.9e-20 72.2 1.7 1.9e-20 72.2 1.2 2.0 2 1 0 2 2 2 1 Ribosomal L29 protein Dynamitin PF04912.9 CBZ56210.1 - 0.0098 14.7 0.5 0.011 14.6 0.3 1.1 1 0 0 1 1 1 1 Dynamitin Snapin_Pallidin PF14712.1 CBZ56210.1 - 0.0099 16.1 1.6 0.0099 16.1 1.1 2.1 2 0 0 2 2 2 1 Snapin/Pallidin Spc42p PF11544.3 CBZ56210.1 - 0.051 13.5 3.1 0.041 13.7 1.2 1.6 1 1 1 2 2 2 0 Spindle pole body component Spc42p Ribosomal_S9 PF00380.14 CBZ56210.1 - 0.06 13.5 4.9 0.081 13.1 3.4 1.3 1 0 0 1 1 1 0 Ribosomal protein S9/S16 DNA_methylase PF00145.12 CBZ56210.1 - 0.11 11.6 1.6 0.12 11.4 1.1 1.0 1 0 0 1 1 1 0 C-5 cytosine-specific DNA methylase ATP-synt_DE PF00401.15 CBZ56210.1 - 0.27 11.1 3.1 1 9.3 0.2 2.3 2 0 0 2 2 2 0 ATP synthase, Delta/Epsilon chain, long alpha-helix domain Ribosomal_L44 PF00935.14 CBZ56210.1 - 0.46 10.5 8.8 0.87 9.6 6.1 1.4 1 0 0 1 1 1 0 Ribosomal protein L44 DivIVA PF05103.8 CBZ56210.1 - 3.1 7.8 8.7 8 6.5 6.0 1.6 1 1 0 1 1 1 0 DivIVA protein SAC3_GANP PF03399.11 CBZ56212.1 - 1.8e-14 53.7 0.0 3e-14 53.0 0.0 1.3 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 CBZ56212.1 - 8e-11 41.8 0.3 4.4e-10 39.4 0.2 2.0 1 1 0 1 1 1 1 COP9 signalosome, subunit CSN8 FliD_N PF02465.13 CBZ56213.1 - 0.013 15.8 0.1 0.013 15.8 0.1 3.9 2 2 1 4 4 4 0 Flagellar hook-associated protein 2 N-terminus Pkinase PF00069.20 CBZ56214.1 - 8.6e-30 103.7 0.0 3.7e-10 39.3 0.0 4.2 4 0 0 4 4 4 4 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ56214.1 - 4.3e-10 39.0 0.2 0.00035 19.7 0.1 3.1 3 0 0 3 3 3 3 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 CBZ56214.1 - 0.72 8.5 0.0 1 8.0 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase zf-DHHC PF01529.15 CBZ56215.1 - 4.3e-23 81.5 3.0 4.3e-23 81.5 2.1 2.4 2 1 1 3 3 3 1 DHHC palmitoyltransferase PfkB PF00294.19 CBZ56216.1 - 3.5e-47 160.9 1.1 6.7e-47 160.0 0.8 1.3 1 1 0 1 1 1 1 pfkB family carbohydrate kinase DNA_pol_A_exo1 PF01612.15 CBZ56217.1 - 8.7e-13 48.1 0.0 1.3e-12 47.5 0.0 1.2 1 0 0 1 1 1 1 3'-5' exonuclease Nuc_recep-AF1 PF11825.3 CBZ56219.1 - 0.17 11.8 4.6 0.3 11.0 3.2 1.5 1 0 0 1 1 1 0 Nuclear/hormone receptor activator site AF-1 Dicistro_VP4 PF11492.3 CBZ56219.1 - 0.8 9.7 2.9 2 8.4 2.0 1.7 1 1 0 1 1 1 0 Cricket paralysis virus, VP4 Mlf1IP PF10248.4 CBZ56220.1 - 1 8.9 6.0 2.5 7.7 4.1 1.6 1 0 0 1 1 1 0 Myelodysplasia-myeloid leukemia factor 1-interacting protein TPR_9 PF13371.1 CBZ56221.1 - 2.9e-05 23.8 1.1 2.9e-05 23.8 0.8 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.12 CBZ56221.1 - 6.3e-05 22.5 4.8 0.0012 18.5 0.2 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat Apc3 PF12895.2 CBZ56221.1 - 0.002 18.2 4.2 0.0068 16.5 1.2 2.3 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 CBZ56221.1 - 0.0039 17.0 1.3 0.0098 15.8 0.1 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.23 CBZ56221.1 - 0.01 15.4 3.4 0.012 15.1 0.2 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.1 CBZ56221.1 - 0.014 15.0 1.0 0.014 15.0 0.7 2.5 2 1 1 3 3 3 0 TPR repeat TPR_6 PF13174.1 CBZ56221.1 - 0.033 14.6 2.3 2.6 8.7 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat IFRD PF05004.8 CBZ56221.1 - 0.035 13.2 2.8 0.89 8.5 0.1 2.1 2 0 0 2 2 2 0 Interferon-related developmental regulator (IFRD) TPR_16 PF13432.1 CBZ56221.1 - 0.038 14.6 1.3 0.1 13.3 0.1 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 CBZ56221.1 - 0.052 14.1 0.6 0.32 11.7 0.2 2.5 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.1 CBZ56221.1 - 0.22 11.9 3.5 0.73 10.2 0.1 2.6 2 1 1 3 3 2 0 Tetratricopeptide repeat Rieske PF00355.21 CBZ56224.1 - 8.1e-06 25.3 0.1 1.1e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.1 CBZ56224.1 - 0.00018 21.1 0.0 0.00027 20.6 0.0 1.4 1 1 0 1 1 1 1 Rieske-like [2Fe-2S] domain UPF0016 PF01169.14 CBZ56225.1 - 7.2e-31 106.1 17.7 1.1e-19 70.3 2.0 2.3 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 eIF3_p135 PF12807.2 CBZ56226.1 - 7.1e-15 55.3 0.0 1.3e-14 54.4 0.0 1.5 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit 135 CLU_N PF15044.1 CBZ56226.1 - 4.2e-11 42.8 0.0 8.1e-11 41.9 0.0 1.5 1 0 0 1 1 1 1 Mitochondrial function, CLU-N-term TPR_12 PF13424.1 CBZ56226.1 - 1.7e-10 40.6 0.7 4.3e-05 23.3 0.0 5.1 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_11 PF13414.1 CBZ56226.1 - 2.9e-07 30.0 0.0 0.003 17.1 0.0 2.9 2 0 0 2 2 2 2 TPR repeat CLU PF13236.1 CBZ56226.1 - 2e-06 27.4 0.0 0.0019 17.6 0.0 2.4 2 0 0 2 2 2 2 Clustered mitochondria TPR_2 PF07719.12 CBZ56226.1 - 0.022 14.6 4.1 2.1 8.4 0.2 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF1319 PF07028.6 CBZ56227.1 - 0.0079 16.3 0.5 0.015 15.5 0.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1319) CR6_interact PF10147.4 CBZ56227.1 - 0.053 12.8 0.4 0.085 12.1 0.3 1.3 1 0 0 1 1 1 0 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 KfrA_N PF11740.3 CBZ56227.1 - 0.35 11.3 9.4 0.11 12.9 3.2 2.2 2 0 0 2 2 2 0 Plasmid replication region DNA-binding N-term EF-hand_8 PF13833.1 CBZ56229.1 - 1.5e-08 34.1 0.1 0.0086 15.6 0.0 3.0 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.1 CBZ56229.1 - 3.8e-05 23.2 2.0 0.021 14.6 0.3 3.5 4 1 0 4 4 4 2 EF-hand domain EF-hand_7 PF13499.1 CBZ56229.1 - 4.3e-05 23.5 1.3 0.0016 18.5 0.9 2.2 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.27 CBZ56229.1 - 4.8e-05 22.3 1.3 0.11 11.8 0.1 3.0 3 0 0 3 3 3 2 EF hand EF-hand_9 PF14658.1 CBZ56229.1 - 0.00011 22.0 0.0 0.48 10.3 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain WD40 PF00400.27 CBZ56230.1 - 0.0028 17.4 1.6 0.21 11.5 0.0 4.1 4 0 0 4 4 4 1 WD domain, G-beta repeat LEA_4 PF02987.11 CBZ56231.1 - 1.1e-08 34.8 16.0 0.024 14.5 0.8 4.6 2 1 0 4 4 4 4 Late embryogenesis abundant protein Herpes_LMP1 PF05297.6 CBZ56231.1 - 7.8e-05 21.7 13.5 0.085 11.7 0.9 3.3 1 1 2 3 3 3 3 Herpesvirus latent membrane protein 1 (LMP1) Apolipoprotein PF01442.13 CBZ56231.1 - 0.00064 19.2 10.9 0.00064 19.2 7.5 3.5 4 0 0 4 4 4 1 Apolipoprotein A1/A4/E domain DUF3826 PF12875.2 CBZ56231.1 - 4.9 6.8 14.2 9.4 5.8 3.7 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3826) CytochromB561_N PF09786.4 CBZ56231.1 - 5.9 5.2 21.6 11 4.3 15.0 1.4 1 0 0 1 1 1 0 Cytochrome B561, N terminal ATP_synt_H PF05493.8 CBZ56232.1 - 4.5e-16 58.6 3.6 6.3e-16 58.1 2.5 1.2 1 0 0 1 1 1 1 ATP synthase subunit H CD34_antigen PF06365.7 CBZ56232.1 - 0.053 13.1 0.0 0.066 12.8 0.0 1.2 1 0 0 1 1 1 0 CD34/Podocalyxin family MFS_2 PF13347.1 CBZ56232.1 - 0.075 11.4 2.6 0.1 10.9 1.8 1.2 1 0 0 1 1 1 0 MFS/sugar transport protein DUF2142 PF09913.4 CBZ56232.1 - 0.084 11.5 0.1 0.092 11.3 0.1 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2142) Otopetrin PF03189.8 CBZ56232.1 - 0.088 11.7 0.0 0.1 11.5 0.0 1.1 1 0 0 1 1 1 0 Otopetrin DUF4131 PF13567.1 CBZ56232.1 - 0.11 11.9 0.2 0.11 11.8 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) Syndecan PF01034.15 CBZ56232.1 - 0.14 11.8 3.9 0.16 11.6 0.0 2.3 2 1 0 2 2 2 0 Syndecan domain Arif-1 PF06770.6 CBZ56232.1 - 0.16 11.3 2.7 0.19 11.0 1.9 1.1 1 0 0 1 1 1 0 Actin-rearrangement-inducing factor (Arif-1) DUF912 PF06024.7 CBZ56232.1 - 0.27 11.2 2.0 0.53 10.3 0.0 1.9 1 1 1 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DEAD PF00270.24 CBZ56233.1 - 1.5e-36 125.4 0.7 2.5e-34 118.1 0.2 3.0 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CBZ56233.1 - 2.3e-17 62.6 0.0 5.8e-17 61.3 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 CBZ56233.1 - 1.6e-11 43.5 0.0 4e-11 42.2 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.10 CBZ56233.1 - 0.085 12.6 0.1 0.44 10.3 0.0 2.4 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit DUF4137 PF13593.1 CBZ56233.1 - 0.17 10.9 0.1 0.68 8.9 0.0 1.8 2 0 0 2 2 2 0 SBF-like CPA transporter family (DUF4137) SDA1 PF05285.7 CBZ56233.1 - 0.4 9.9 33.0 0.15 11.3 9.6 3.4 3 0 0 3 3 3 0 SDA1 Spore_coat_CotO PF14153.1 CBZ56233.1 - 2.6 7.4 14.4 0.058 12.8 1.0 3.1 3 0 0 3 3 3 0 Spore coat protein CotO DUF159 PF02586.9 CBZ56234.1 - 1.6e-40 138.8 0.0 8.8e-40 136.4 0.0 1.9 2 0 0 2 2 2 1 Uncharacterised ACR, COG2135 JAB PF01398.16 CBZ56235.1 - 1.4e-09 37.6 0.1 5.7e-08 32.5 0.0 2.4 1 1 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Bac_DNA_binding PF00216.16 CBZ56235.1 - 0.083 12.9 0.2 0.18 11.8 0.1 1.5 1 0 0 1 1 1 0 Bacterial DNA-binding protein Peptidase_C48 PF02902.14 CBZ56236.1 - 1.5e-18 67.2 1.0 2.4e-17 63.3 0.7 2.2 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Collagen PF01391.13 CBZ56236.1 - 1.7e-08 33.8 32.0 1.7e-08 33.8 22.2 4.9 3 1 0 3 3 3 1 Collagen triple helix repeat (20 copies) NARP1 PF12569.3 CBZ56236.1 - 3.2 6.4 7.9 5.9 5.5 5.4 1.3 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Ycf1 PF05758.7 CBZ56236.1 - 6.4 4.3 4.7 10 3.6 3.2 1.2 1 0 0 1 1 1 0 Ycf1 ACBP PF00887.14 CBZ56239.1 - 1.6e-29 101.4 0.7 1.8e-29 101.2 0.5 1.0 1 0 0 1 1 1 1 Acyl CoA binding protein UVR PF02151.14 CBZ56239.1 - 0.34 10.5 5.3 0.35 10.4 0.7 2.2 2 0 0 2 2 2 0 UvrB/uvrC motif Abi PF02517.11 CBZ56241.1 - 1.5e-14 53.8 7.4 1.5e-14 53.8 5.2 2.6 4 0 0 4 4 4 1 CAAX protease self-immunity Brix PF04427.13 CBZ56243.1 - 1.2e-43 148.9 1.0 2.1e-43 148.1 0.7 1.4 1 0 0 1 1 1 1 Brix domain XPG_I PF00867.13 CBZ56245.1 - 5.7e-30 103.2 0.1 5.7e-30 103.2 0.0 2.1 2 0 0 2 2 2 1 XPG I-region XPG_N PF00752.12 CBZ56245.1 - 7.4e-27 93.5 0.0 2.8e-26 91.6 0.0 2.1 2 0 0 2 2 2 1 XPG N-terminal domain 5_3_exonuc PF01367.15 CBZ56245.1 - 3.2e-06 27.3 0.3 2e-05 24.7 0.0 2.4 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold Nop14 PF04147.7 CBZ56245.1 - 0.42 8.4 34.5 0.68 7.7 23.9 1.2 1 0 0 1 1 1 0 Nop14-like family Cation_efflux PF01545.16 CBZ56246.1 - 3.4e-60 203.5 0.8 4.4e-60 203.1 0.5 1.1 1 0 0 1 1 1 1 Cation efflux family UQ_con PF00179.21 CBZ56247.1 - 3.6e-16 58.8 0.0 4.2e-16 58.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme DUF1103 PF06513.6 CBZ56248.1 - 0.099 12.0 21.1 0.045 13.1 12.7 1.7 1 1 0 1 1 1 0 Repeat of unknown function (DUF1103) GETHR PF05671.6 CBZ56248.1 - 0.57 9.3 13.4 7.3e+02 -0.6 0.0 4.8 2 2 0 2 2 2 0 GETHR pentapeptide repeat (5 copies) SOBP PF15279.1 CBZ56248.1 - 0.61 10.4 19.5 0.85 9.9 13.5 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein MgsA_C PF12002.3 CBZ56249.1 - 6.2e-54 182.1 0.1 1.1e-53 181.3 0.1 1.4 1 0 0 1 1 1 1 MgsA AAA+ ATPase C terminal RuvB_N PF05496.7 CBZ56249.1 - 1.2e-14 53.9 0.1 1.3e-09 37.4 0.0 2.6 1 1 1 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA PF00004.24 CBZ56249.1 - 6.6e-13 48.9 0.0 1.9e-12 47.5 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 CBZ56249.1 - 7.1e-08 32.2 0.0 1.4e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) TIP49 PF06068.8 CBZ56249.1 - 3.5e-06 25.9 0.0 0.0064 15.2 0.0 2.2 1 1 1 2 2 2 2 TIP49 C-terminus Mg_chelatase PF01078.16 CBZ56249.1 - 8.9e-06 25.0 0.4 0.036 13.2 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_14 PF13173.1 CBZ56249.1 - 2.7e-05 24.0 0.0 5.9e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 CBZ56249.1 - 7.4e-05 22.8 3.8 0.036 14.0 0.1 2.9 2 1 0 3 3 3 2 AAA ATPase domain Sigma54_activat PF00158.21 CBZ56249.1 - 8.5e-05 22.0 0.0 0.00099 18.6 0.0 2.1 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_22 PF13401.1 CBZ56249.1 - 0.0011 19.1 0.9 0.21 11.7 0.6 2.9 1 1 0 1 1 1 1 AAA domain DNA_pol3_delta2 PF13177.1 CBZ56249.1 - 0.015 14.9 0.0 0.074 12.7 0.0 1.7 1 1 0 1 1 1 0 DNA polymerase III, delta subunit Viral_helicase1 PF01443.13 CBZ56249.1 - 0.017 14.6 0.0 0.034 13.6 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase DNA_pol3_delta PF06144.8 CBZ56249.1 - 0.035 13.6 0.1 0.057 12.9 0.0 1.3 1 0 0 1 1 1 0 DNA polymerase III, delta subunit AAA_2 PF07724.9 CBZ56249.1 - 0.043 13.7 0.0 0.091 12.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) Sigma54_activ_2 PF14532.1 CBZ56249.1 - 0.048 13.6 0.0 0.11 12.5 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_19 PF13245.1 CBZ56249.1 - 0.064 13.0 0.9 0.2 11.4 0.0 2.3 2 0 0 2 2 2 0 Part of AAA domain AAA_3 PF07726.6 CBZ56249.1 - 0.066 12.8 0.0 0.16 11.5 0.0 1.7 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 CBZ56249.1 - 0.088 12.1 0.0 0.25 10.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain HEAT_2 PF13646.1 CBZ56249.1 - 0.099 12.9 1.2 0.96 9.7 0.2 2.6 2 0 0 2 2 2 0 HEAT repeats Arch_ATPase PF01637.13 CBZ56249.1 - 0.14 11.8 0.0 6.4 6.3 0.0 2.5 1 1 1 2 2 2 0 Archaeal ATPase MAR_sialic_bdg PF10564.4 CBZ56250.1 - 1.5e-36 124.1 22.2 1.3e-15 56.9 4.0 3.4 2 1 1 3 3 3 3 Sialic-acid binding micronemal adhesive repeat TCTP PF00838.12 CBZ56251.1 - 5.2e-47 159.8 0.5 6e-47 159.7 0.4 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein tRNA-synt_2b PF00587.20 CBZ56252.1 - 2.4e-33 115.1 0.0 3.6e-33 114.5 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.17 CBZ56252.1 - 5.5e-21 74.6 3.4 1.1e-20 73.6 2.3 1.5 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain Hormone_1 PF00103.15 CBZ56252.1 - 0.09 12.1 0.1 0.28 10.4 0.0 1.8 1 1 1 2 2 2 0 Somatotropin hormone family DUF4337 PF14235.1 CBZ56252.1 - 0.17 11.6 5.5 0.15 11.9 1.5 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4337) V-SNARE_C PF12352.3 CBZ56253.1 - 0.00018 21.5 0.0 0.0016 18.4 0.0 2.1 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.8 CBZ56253.1 - 0.0047 16.6 0.6 0.023 14.4 0.0 2.2 2 1 0 2 2 2 1 Sec20 FliJ PF02050.11 CBZ56253.1 - 0.046 13.7 1.2 0.26 11.3 0.1 2.4 2 1 1 3 3 3 0 Flagellar FliJ protein HisKA_3 PF07730.8 CBZ56253.1 - 6.7 7.1 7.3 1.8 8.9 1.4 2.6 2 2 0 2 2 2 0 Histidine kinase AP2 PF00847.15 CBZ56255.1 - 1.2e-08 34.9 0.2 3.5e-08 33.4 0.0 1.9 2 0 0 2 2 2 1 AP2 domain MORN PF02493.15 CBZ56256.1 - 8e-23 78.7 42.6 1.8e-05 24.1 1.3 7.5 7 1 0 7 7 7 6 MORN repeat PA28_beta PF02252.13 CBZ56257.1 - 3.7e-58 195.2 0.2 6.2e-58 194.5 0.1 1.3 1 0 0 1 1 1 1 Proteasome activator pa28 beta subunit PA28_alpha PF02251.13 CBZ56257.1 - 0.052 13.7 0.6 0.099 12.8 0.1 1.7 2 0 0 2 2 2 0 Proteasome activator pa28 alpha subunit HSP70 PF00012.15 CBZ56259.1 - 5.2e-268 889.9 12.8 6.1e-268 889.7 8.9 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 CBZ56259.1 - 5.2e-15 54.8 5.2 7.8e-14 51.0 1.3 2.5 2 0 0 2 2 2 2 MreB/Mbl protein FtsA PF14450.1 CBZ56259.1 - 0.00033 20.4 2.4 0.71 9.7 0.0 3.7 2 1 0 2 2 2 2 Cell division protein FtsA FGGY_C PF02782.11 CBZ56259.1 - 0.0014 18.3 0.1 0.0055 16.3 0.1 2.1 2 1 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain HBS1_N PF08938.5 CBZ56259.1 - 0.029 14.4 1.8 0.091 12.8 1.2 1.8 1 0 0 1 1 1 0 HBS1 N-terminus zf-RanBP PF00641.13 CBZ56260.1 - 0.022 13.8 6.7 0.045 12.8 4.6 1.5 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others CDC45 PF02724.9 CBZ56260.1 - 4.8 5.1 7.7 6.2 4.7 5.3 1.1 1 0 0 1 1 1 0 CDC45-like protein eIF-5a PF01287.15 CBZ56262.1 - 1.3e-25 89.0 0.2 2e-25 88.5 0.2 1.3 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold EFP_N PF08207.7 CBZ56262.1 - 0.0013 18.5 0.0 0.0022 17.8 0.0 1.4 1 0 0 1 1 1 1 Elongation factor P (EF-P) KOW-like domain KOW PF00467.24 CBZ56262.1 - 0.051 13.3 0.1 0.12 12.1 0.1 1.6 1 0 0 1 1 1 0 KOW motif Phage_NinH PF06322.6 CBZ56263.1 - 0.064 12.8 0.0 1.7 8.3 0.0 2.9 3 0 0 3 3 3 0 Phage NinH protein Pacs-1 PF10254.4 CBZ56263.1 - 0.21 10.1 0.3 0.3 9.6 0.2 1.2 1 0 0 1 1 1 0 PACS-1 cytosolic sorting protein cEGF PF12662.2 CBZ56263.1 - 5.5 6.7 18.0 5.1 6.8 0.1 5.1 5 0 0 5 5 5 0 Complement Clr-like EGF-like Macoilin PF09726.4 CBZ56264.1 - 3.8 5.6 15.4 5.5 5.1 10.7 1.1 1 0 0 1 1 1 0 Transmembrane protein Metallophos PF00149.23 CBZ56265.1 - 5e-27 94.6 0.4 8.8e-27 93.7 0.2 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase EF-hand_7 PF13499.1 CBZ56265.1 - 7.1e-21 74.1 7.4 1.7e-09 37.6 0.1 4.5 4 0 0 4 4 4 3 EF-hand domain pair EF-hand_1 PF00036.27 CBZ56265.1 - 3.7e-19 66.5 7.2 0.00042 19.4 0.0 6.7 7 0 0 7 7 7 5 EF hand EF-hand_8 PF13833.1 CBZ56265.1 - 1.2e-16 59.9 9.1 8.5e-11 41.3 0.2 5.5 6 0 0 6 6 6 2 EF-hand domain pair CAP_GLY PF01302.20 CBZ56265.1 - 5.7e-16 57.9 0.2 1.3e-15 56.7 0.1 1.7 1 0 0 1 1 1 1 CAP-Gly domain EF-hand_6 PF13405.1 CBZ56265.1 - 1.5e-12 46.2 9.9 0.036 13.9 0.0 6.9 4 1 1 5 5 5 4 EF-hand domain EF-hand_5 PF13202.1 CBZ56265.1 - 8.7e-10 37.4 5.6 0.00086 18.5 0.0 4.9 5 0 0 5 5 5 3 EF hand PPP5 PF08321.7 CBZ56265.1 - 3e-05 23.9 0.0 0.00013 21.8 0.0 2.1 1 0 0 1 1 1 1 PPP5 TPR repeat region IQ PF00612.22 CBZ56265.1 - 0.00025 20.3 1.7 0.00075 18.9 1.2 1.9 1 0 0 1 1 1 1 IQ calmodulin-binding motif EF-hand_4 PF12763.2 CBZ56265.1 - 0.0025 17.5 0.3 0.23 11.2 0.0 3.7 4 1 0 4 4 4 1 Cytoskeletal-regulatory complex EF hand DUF1880 PF08976.6 CBZ56265.1 - 0.023 14.8 0.1 1.1 9.4 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF1880) Histone PF00125.19 CBZ56266.1 - 3.4e-19 68.7 0.1 4.6e-19 68.3 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 CBZ56266.1 - 0.00028 20.8 0.2 0.00057 19.8 0.1 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.8 CBZ56266.1 - 0.00029 21.0 0.0 0.0005 20.2 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A tRNA-synt_1b PF00579.20 CBZ56267.1 - 3e-58 197.2 0.0 3.7e-58 196.9 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) AftA_N PF12250.3 CBZ56269.1 - 0.036 12.8 0.5 0.04 12.6 0.4 1.1 1 0 0 1 1 1 0 Arabinofuranosyltransferase N terminal Es2 PF09751.4 CBZ56271.1 - 7.1e-33 114.6 12.3 8.9e-32 111.0 4.9 2.5 2 1 0 2 2 2 1 Nuclear protein Es2 adh_short_C2 PF13561.1 CBZ56272.1 - 3.9e-74 249.4 0.3 4.5e-41 141.1 0.0 3.1 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase LRR_4 PF12799.2 CBZ56273.1 - 2.7e-22 77.9 13.4 4.3e-06 26.2 0.1 5.5 3 2 3 6 6 6 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CBZ56273.1 - 7e-09 35.3 16.4 0.011 15.5 1.3 4.6 2 2 4 6 6 6 6 Leucine rich repeat LRR_7 PF13504.1 CBZ56273.1 - 7.9e-08 31.2 8.9 6.6 7.4 0.0 8.2 7 2 0 7 7 7 2 Leucine rich repeat LRR_1 PF00560.28 CBZ56273.1 - 2.2e-07 29.9 18.9 0.52 10.5 0.1 7.8 4 3 2 6 6 6 2 Leucine Rich Repeat LRR_9 PF14580.1 CBZ56273.1 - 0.00036 20.1 2.1 0.031 13.8 0.2 2.6 1 1 0 2 2 2 2 Leucine-rich repeat LRR_6 PF13516.1 CBZ56273.1 - 0.0099 15.8 15.4 3.2 8.0 0.5 6.7 4 1 3 7 7 7 2 Leucine Rich repeat SeqA PF03925.8 CBZ56273.1 - 0.13 11.9 1.2 0.58 9.8 1.2 1.6 2 0 0 2 2 2 0 SeqA protein Ribosomal_L12 PF00542.14 CBZ56274.1 - 2.1e-24 85.2 9.6 3.2e-22 78.3 4.9 2.3 2 0 0 2 2 2 2 Ribosomal protein L7/L12 C-terminal domain SAG PF04092.8 CBZ56275.1 - 4.1e-18 65.9 15.3 1e-06 29.1 0.1 3.2 3 0 0 3 3 3 3 SRS domain DUF4109 PF13397.1 CBZ56275.1 - 0.061 13.7 0.1 0.24 11.7 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4109) BCSC_C PF05420.6 CBZ56275.1 - 0.18 10.8 0.0 0.29 10.2 0.0 1.2 1 0 0 1 1 1 0 Cellulose synthase operon protein C C-terminus (BCSC_C) Mito_carr PF00153.22 CBZ56276.1 - 4.9e-34 115.9 11.8 4.1e-19 68.0 0.2 3.6 3 1 0 3 3 3 3 Mitochondrial carrier protein ArsB PF02040.10 CBZ56276.1 - 0.025 13.5 0.2 0.037 12.9 0.1 1.2 1 0 0 1 1 1 0 Arsenical pump membrane protein Peptidase_C14 PF00656.17 CBZ56278.1 - 8.1e-31 107.5 0.0 1.3e-30 106.8 0.0 1.3 1 0 0 1 1 1 1 Caspase domain LSM PF01423.17 CBZ56281.1 - 7.1e-14 51.1 0.0 1.1e-13 50.5 0.0 1.3 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 CBZ56281.1 - 0.058 13.3 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 Ataxin 2 SM domain SLBB PF10531.4 CBZ56281.1 - 0.087 12.7 0.0 0.2 11.5 0.0 1.6 1 0 0 1 1 1 0 SLBB domain HDA2-3 PF11496.3 CBZ56281.1 - 0.12 11.1 0.0 0.15 10.8 0.0 1.1 1 0 0 1 1 1 0 Class II histone deacetylase complex subunits 2 and 3 HECT PF00632.20 CBZ56282.1 - 9.1e-80 268.1 0.0 1.1e-79 267.8 0.0 1.1 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) TTL PF03133.10 CBZ56283.1 - 3.8e-37 127.8 0.1 2e-28 99.1 0.0 2.1 2 0 0 2 2 2 2 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.1 CBZ56283.1 - 1.1e-05 24.3 0.0 0.00074 18.3 0.0 2.2 2 0 0 2 2 2 2 YheC/D like ATP-grasp PALP PF00291.20 CBZ56285.1 - 2.2e-38 132.2 0.0 2.8e-24 85.8 0.0 2.2 1 1 1 2 2 2 2 Pyridoxal-phosphate dependent enzyme Kdo PF06293.9 CBZ56286.1 - 1.8e-05 23.9 0.0 7.1e-05 21.9 0.0 1.9 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.20 CBZ56286.1 - 0.0014 17.8 0.0 0.049 12.7 0.0 2.2 2 0 0 2 2 2 1 Protein kinase domain RIO1 PF01163.17 CBZ56286.1 - 0.13 11.6 0.0 0.29 10.4 0.0 1.5 1 0 0 1 1 1 0 RIO1 family APH PF01636.18 CBZ56286.1 - 0.33 10.6 8.0 0.35 10.5 0.5 3.3 3 1 0 3 3 3 0 Phosphotransferase enzyme family CASP_C PF08172.7 CBZ56287.1 - 5.6e-09 35.3 0.4 5.6e-09 35.3 0.3 4.3 3 1 0 3 3 3 2 CASP C terminal Ribophorin_I PF04597.9 CBZ56287.1 - 2.8 6.3 3.8 4.3 5.7 2.7 1.2 1 0 0 1 1 1 0 Ribophorin I GDA1_CD39 PF01150.12 CBZ56288.1 - 3.4e-68 230.1 0.0 5.3e-68 229.4 0.0 1.3 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Myosin_head PF00063.16 CBZ56289.1 - 3.8e-190 633.3 0.5 3.6e-189 630.1 0.0 2.4 3 0 0 3 3 3 1 Myosin head (motor domain) WD40 PF00400.27 CBZ56289.1 - 4.1e-13 48.6 6.6 0.00095 18.9 0.3 7.1 7 0 0 7 7 7 3 WD domain, G-beta repeat AAA_22 PF13401.1 CBZ56289.1 - 0.00036 20.6 0.1 0.95 9.6 0.0 3.5 4 0 0 4 4 4 2 AAA domain Miro PF08477.8 CBZ56289.1 - 0.0028 18.1 0.0 0.03 14.8 0.0 2.7 2 0 0 2 2 2 1 Miro-like protein AAA_5 PF07728.9 CBZ56289.1 - 0.01 15.5 0.1 0.078 12.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) IQ PF00612.22 CBZ56289.1 - 0.03 13.9 42.0 0.087 12.5 0.8 7.0 7 0 0 7 7 7 0 IQ calmodulin-binding motif AAA_29 PF13555.1 CBZ56289.1 - 0.071 12.6 0.0 6.5 6.3 0.1 2.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain RNA_helicase PF00910.17 CBZ56289.1 - 0.093 12.9 0.0 15 5.8 0.0 2.9 3 0 0 3 3 3 0 RNA helicase AAA_17 PF13207.1 CBZ56289.1 - 0.1 13.3 0.7 11 6.9 0.0 3.8 3 1 0 3 3 3 0 AAA domain KaiC PF06745.8 CBZ56289.1 - 0.18 10.8 0.1 10 5.1 0.1 2.6 2 0 0 2 2 2 0 KaiC ABC_tran PF00005.22 CBZ56289.1 - 0.31 11.3 5.2 5 7.4 0.0 3.8 3 1 0 3 3 2 0 ABC transporter TBPIP PF07106.8 CBZ56289.1 - 2.5 7.6 21.0 0.57 9.6 5.6 2.9 3 0 0 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) TMF_DNA_bd PF12329.3 CBZ56289.1 - 9.2 6.1 33.6 0.78 9.5 5.6 2.9 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding zf-DHHC PF01529.15 CBZ56291.1 - 2e-37 128.2 13.3 2e-37 128.2 9.2 2.1 1 1 1 2 2 2 1 DHHC palmitoyltransferase DUF4351 PF14261.1 CBZ56292.1 - 0.11 12.3 0.2 0.2 11.5 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4351) G6PD_C PF02781.11 CBZ56293.1 - 1.7e-109 365.1 0.0 2.5e-109 364.6 0.0 1.1 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.17 CBZ56293.1 - 1.3e-56 191.6 0.0 2.9e-56 190.5 0.0 1.5 2 0 0 2 2 2 1 Glucose-6-phosphate dehydrogenase, NAD binding domain Glucosamine_iso PF01182.15 CBZ56293.1 - 1.2e-32 113.2 0.0 2.1e-32 112.4 0.0 1.3 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase MFS_1 PF07690.11 CBZ56296.1 - 9.3e-31 106.8 23.6 2.7e-22 78.9 3.7 3.6 3 1 0 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.19 CBZ56296.1 - 0.27 9.7 9.8 0.1 11.1 1.1 2.3 2 0 0 2 2 2 0 Sugar (and other) transporter ubiquitin PF00240.18 CBZ56297.1 - 1.6e-07 30.6 0.0 2.7e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 CBZ56297.1 - 0.0019 17.8 0.0 0.0037 16.9 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Cadherin_2 PF08266.7 CBZ56297.1 - 0.25 10.9 0.9 3.8 7.1 0.3 2.4 2 1 0 2 2 2 0 Cadherin-like Hydrolase PF00702.21 CBZ56298.1 - 0.0057 17.0 0.0 0.023 15.0 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase CAF-1_p150 PF11600.3 CBZ56300.1 - 0.0083 15.5 13.6 0.0083 15.5 9.5 1.9 2 0 0 2 2 2 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal Hamartin PF04388.7 CBZ56300.1 - 7.7 5.0 11.3 10 4.6 7.9 1.1 1 0 0 1 1 1 0 Hamartin protein Orn_Arg_deC_N PF02784.11 CBZ56301.1 - 4.6e-37 127.5 0.0 6.8e-37 127.0 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.17 CBZ56301.1 - 1.3e-13 50.6 0.0 2.5e-13 49.7 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain WD40 PF00400.27 CBZ56302.1 - 0.00014 21.6 0.0 1.6 8.7 0.0 3.6 3 0 0 3 3 3 2 WD domain, G-beta repeat Chor_lyase PF04345.8 CBZ56305.1 - 0.053 12.9 0.0 0.094 12.1 0.0 1.3 1 0 0 1 1 1 0 Chorismate lyase CPW_WPC PF09717.5 CBZ56306.1 - 7.1e-07 29.7 0.1 1.2e-06 29.0 0.0 1.3 1 0 0 1 1 1 1 Plasmodium falciparum domain of unknown function (CPW_WPC) UQ_con PF00179.21 CBZ56308.1 - 2.4e-17 62.6 0.0 4.6e-17 61.7 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_A PF14457.1 CBZ56308.1 - 0.01 15.3 0.0 0.017 14.6 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic E2 family A E1-E2_ATPase PF00122.15 CBZ56310.1 - 1.7e-60 203.9 4.3 2.8e-60 203.2 3.0 1.4 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 CBZ56310.1 - 2.3e-33 115.2 0.0 2.3e-33 115.2 0.0 2.4 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 CBZ56310.1 - 4.9e-33 115.3 1.1 1.4e-27 97.5 0.1 2.9 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 CBZ56310.1 - 1.8e-21 75.3 0.2 6.9e-21 73.4 0.1 2.1 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 CBZ56310.1 - 2.5e-17 63.6 0.1 3e-16 60.1 0.0 2.6 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 CBZ56310.1 - 1.3e-15 57.1 0.0 3.6e-15 55.6 0.0 1.8 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 CBZ56310.1 - 2.8e-06 27.1 1.4 0.0015 18.1 0.5 2.7 2 1 1 3 3 3 2 haloacid dehalogenase-like hydrolase DUF1287 PF06940.6 CBZ56310.1 - 0.071 12.5 0.0 0.18 11.2 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1287) Hydrolase_6 PF13344.1 CBZ56310.1 - 0.082 12.8 0.0 0.26 11.1 0.0 1.8 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 CBZ56310.1 - 0.11 12.7 0.0 0.47 10.6 0.0 2.1 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase zf-MIZ PF02891.15 CBZ56311.1 - 2.2e-16 59.1 3.3 5.3e-16 57.8 2.3 1.7 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger SAP PF02037.22 CBZ56311.1 - 0.00019 20.8 0.0 0.00039 19.8 0.0 1.5 1 0 0 1 1 1 1 SAP domain PINIT PF14324.1 CBZ56311.1 - 0.00039 20.5 0.1 0.00061 19.8 0.1 1.3 1 0 0 1 1 1 1 PINIT domain zf-Nse PF11789.3 CBZ56311.1 - 0.09 12.3 1.5 0.18 11.3 1.0 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit PHD PF00628.24 CBZ56311.1 - 0.12 12.1 15.1 0.16 11.6 3.7 2.5 2 0 0 2 2 2 0 PHD-finger DUF2296 PF10058.4 CBZ56311.1 - 5.9 6.7 8.6 24 4.7 0.2 2.9 2 1 0 2 2 2 0 Predicted integral membrane metal-binding protein (DUF2296) TPR_14 PF13428.1 CBZ56312.1 - 6e-06 26.4 0.1 0.0038 17.7 0.0 3.0 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 CBZ56312.1 - 0.00025 21.3 0.3 0.0012 19.0 0.0 1.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.1 CBZ56312.1 - 0.0011 18.5 0.7 0.084 12.5 0.1 2.6 2 1 1 3 3 3 2 TPR repeat TPR_16 PF13432.1 CBZ56312.1 - 0.0031 18.1 0.1 0.041 14.5 0.0 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.1 CBZ56312.1 - 0.0036 17.3 0.3 3 8.2 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.12 CBZ56312.1 - 0.035 14.0 1.1 1.1 9.3 0.0 3.2 4 0 0 4 4 4 0 Tetratricopeptide repeat Septum_form PF13845.1 CBZ56312.1 - 0.13 11.7 0.0 0.15 11.5 0.0 1.1 1 0 0 1 1 1 0 Septum formation TPR_6 PF13174.1 CBZ56312.1 - 0.15 12.5 0.1 2.4 8.7 0.0 2.5 3 0 0 3 3 3 0 Tetratricopeptide repeat FliT PF05400.8 CBZ56312.1 - 1.6 9.1 5.7 5.4 7.5 0.4 2.1 1 1 1 2 2 2 0 Flagellar protein FliT TPR_11 PF13414.1 CBZ56313.1 - 5.1e-15 54.8 1.1 3.8e-12 45.6 0.4 2.3 2 0 0 2 2 2 2 TPR repeat TPR_1 PF00515.23 CBZ56313.1 - 1.9e-12 46.2 0.9 1.1e-05 24.8 0.4 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 CBZ56313.1 - 4e-09 35.6 0.7 0.0011 18.6 0.5 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 CBZ56313.1 - 1.4e-08 35.1 0.5 0.0042 17.7 0.0 2.9 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.1 CBZ56313.1 - 1.5e-08 34.1 0.2 0.0028 17.7 0.1 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.1 CBZ56313.1 - 1.7e-06 27.7 0.7 0.00065 19.5 0.2 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 CBZ56313.1 - 2.6e-06 27.2 0.1 0.0002 21.2 0.1 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 CBZ56313.1 - 2.8e-06 27.4 0.3 0.26 12.0 0.0 3.7 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 CBZ56313.1 - 4.4e-06 26.9 0.1 0.072 13.4 0.0 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 CBZ56313.1 - 1.2e-05 24.6 0.0 0.0027 17.3 0.2 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_20 PF14561.1 CBZ56313.1 - 0.00063 19.8 0.3 0.0047 17.0 0.0 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.1 CBZ56313.1 - 0.0016 18.7 0.7 1.3 9.6 0.3 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat Apc3 PF12895.2 CBZ56313.1 - 0.0054 16.8 0.1 0.58 10.3 0.1 2.3 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 CBZ56313.1 - 0.021 14.6 0.1 46 4.1 0.1 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat SHNi-TPR PF10516.4 CBZ56313.1 - 0.041 13.1 0.0 0.14 11.3 0.0 1.9 1 0 0 1 1 1 0 SHNi-TPR PPR_1 PF12854.2 CBZ56313.1 - 0.1 12.0 0.0 0.29 10.6 0.0 1.8 1 0 0 1 1 1 0 PPR repeat Hid1 PF12722.2 CBZ56313.1 - 1.9 6.0 5.2 2.6 5.6 3.6 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein TM140 PF14985.1 CBZ56317.1 - 0.039 13.6 0.2 0.039 13.6 0.1 1.0 1 0 0 1 1 1 0 TM140 protein family Atg14 PF10186.4 CBZ56319.1 - 0.0027 16.7 1.5 0.003 16.5 1.0 1.1 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 Macoilin PF09726.4 CBZ56319.1 - 0.0063 14.8 2.8 0.0067 14.7 1.9 1.1 1 0 0 1 1 1 1 Transmembrane protein TMF_DNA_bd PF12329.3 CBZ56319.1 - 0.013 15.2 9.6 0.013 15.2 6.6 1.9 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF4337 PF14235.1 CBZ56319.1 - 0.018 14.9 1.3 0.024 14.4 0.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) EzrA PF06160.7 CBZ56319.1 - 0.038 12.1 1.5 0.048 11.8 1.0 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA OmpH PF03938.9 CBZ56319.1 - 0.057 13.3 1.3 0.073 13.0 0.9 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF972 PF06156.8 CBZ56319.1 - 0.073 13.4 3.8 0.14 12.5 2.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF972) Trigger_C PF05698.9 CBZ56319.1 - 0.074 12.8 4.2 0.11 12.3 2.9 1.2 1 0 0 1 1 1 0 Bacterial trigger factor protein (TF) C-terminus IncA PF04156.9 CBZ56319.1 - 0.081 12.5 11.5 0.12 12.0 7.9 1.2 1 0 0 1 1 1 0 IncA protein DivIVA PF05103.8 CBZ56319.1 - 0.087 12.8 3.2 0.14 12.1 2.2 1.3 1 0 0 1 1 1 0 DivIVA protein DUF342 PF03961.8 CBZ56319.1 - 0.097 11.0 0.6 0.12 10.7 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) CENP-F_leu_zip PF10473.4 CBZ56319.1 - 0.11 12.3 9.4 0.23 11.3 6.3 1.7 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 APG6 PF04111.7 CBZ56319.1 - 0.22 10.5 3.4 0.3 10.1 2.4 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Lectin_N PF03954.9 CBZ56319.1 - 0.33 10.3 4.1 0.21 11.0 1.2 1.7 2 1 0 2 2 2 0 Hepatic lectin, N-terminal domain DivIC PF04977.10 CBZ56319.1 - 1.1 8.8 5.5 1.1 8.8 2.8 1.8 1 1 1 2 2 2 0 Septum formation initiator GTP_EFTU PF00009.22 CBZ56320.1 - 1.2e-35 122.6 0.0 4.4e-35 120.8 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 CBZ56320.1 - 4.2e-10 39.4 0.0 8.7e-06 25.5 0.0 2.5 2 0 0 2 2 2 2 Translation-initiation factor 2 MMR_HSR1 PF01926.18 CBZ56320.1 - 4.8e-07 29.7 0.0 1.2e-06 28.4 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 CBZ56320.1 - 4.6e-05 23.9 0.0 0.00011 22.7 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein FeoB_N PF02421.13 CBZ56320.1 - 0.00028 20.1 0.0 0.00051 19.3 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B Ras PF00071.17 CBZ56320.1 - 0.0016 17.8 0.0 0.0033 16.8 0.0 1.5 1 0 0 1 1 1 1 Ras family SRPRB PF09439.5 CBZ56320.1 - 0.0018 17.5 0.0 0.004 16.4 0.0 1.5 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit PduV-EutP PF10662.4 CBZ56320.1 - 0.043 13.3 0.0 0.089 12.2 0.0 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Arf PF00025.16 CBZ56320.1 - 0.28 10.3 0.0 0.53 9.4 0.0 1.3 1 0 0 1 1 1 0 ADP-ribosylation factor family GTP_EFTU_D4 PF14578.1 CBZ56320.1 - 0.45 10.1 0.1 1.8 8.2 0.1 2.0 1 0 0 1 1 1 0 Elongation factor Tu domain 4 Dynamin_N PF00350.18 CBZ56320.1 - 1.1 9.0 7.2 0.87 9.3 0.0 3.1 4 0 0 4 4 3 0 Dynamin family MBF1 PF08523.5 CBZ56322.1 - 9.9e-21 73.5 0.7 9.9e-21 73.5 0.5 2.0 2 0 0 2 2 2 1 Multiprotein bridging factor 1 HTH_3 PF01381.17 CBZ56322.1 - 1.2e-15 57.0 0.1 2e-15 56.3 0.1 1.3 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.1 CBZ56322.1 - 3.3e-11 43.2 0.0 5.7e-11 42.4 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_19 PF12844.2 CBZ56322.1 - 2.8e-09 36.9 0.0 4.6e-09 36.2 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_37 PF13744.1 CBZ56322.1 - 0.0057 16.4 0.5 0.011 15.4 0.3 1.6 1 1 0 1 1 1 1 Helix-turn-helix domain HTH_25 PF13413.1 CBZ56322.1 - 0.0097 15.5 0.0 0.017 14.7 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain Glycos_transf_2 PF00535.21 CBZ56323.1 - 1.4e-20 73.6 0.0 2.5e-20 72.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.17 CBZ56323.1 - 1.2e-14 54.3 0.6 8.8e-11 41.9 0.5 2.3 2 0 0 2 2 2 2 Ricin-type beta-trefoil lectin domain Glyco_transf_7C PF02709.9 CBZ56323.1 - 2.8e-10 39.5 0.0 6.3e-10 38.3 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_3 PF13641.1 CBZ56323.1 - 4.9e-10 39.6 0.0 1.2e-09 38.2 0.0 1.6 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.4 CBZ56323.1 - 0.00012 21.2 0.0 0.0002 20.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 CBZ56323.1 - 0.066 12.9 0.1 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family group 2 PP2C PF00481.16 CBZ56324.1 - 3.6e-42 144.5 0.0 1.2e-34 119.8 0.0 2.1 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.1 CBZ56324.1 - 0.042 13.2 0.0 0.2 11.0 0.0 2.1 1 1 0 1 1 1 0 Protein phosphatase 2C Homeobox PF00046.24 CBZ56324.1 - 0.16 11.5 0.0 0.46 10.1 0.0 1.7 2 0 0 2 2 2 0 Homeobox domain FtsJ PF01728.14 CBZ56325.1 - 4.9e-19 69.0 0.0 1.6e-18 67.3 0.0 1.8 2 0 0 2 2 2 1 FtsJ-like methyltransferase Methyltrans_Mon PF14314.1 CBZ56325.1 - 0.076 10.8 0.1 0.11 10.2 0.0 1.1 1 0 0 1 1 1 0 Virus-capping methyltransferase zf-C3HC4_2 PF13923.1 CBZ56326.1 - 0.0059 16.6 1.2 0.14 12.1 1.4 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Borrelia_P83 PF05262.6 CBZ56326.1 - 0.056 11.7 3.7 0.066 11.4 2.6 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Rtf2 PF04641.7 CBZ56326.1 - 1.9 7.6 17.5 0.6 9.2 0.0 2.7 2 2 1 3 3 3 0 Rtf2 RING-finger FKBP_N PF01346.13 CBZ56326.1 - 9.7 6.2 12.2 19 5.3 8.4 1.4 1 0 0 1 1 1 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase Sec3_C PF09763.4 CBZ56327.1 - 1.4 6.9 5.0 2.1 6.3 3.4 1.2 1 0 0 1 1 1 0 Exocyst complex component Sec3 DUF1556 PF07590.6 CBZ56329.1 - 0.039 14.1 1.4 0.11 12.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1556) SNF2_N PF00176.18 CBZ56330.1 - 5.8e-64 215.7 0.0 1e-63 214.9 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 CBZ56330.1 - 3.3e-14 52.4 0.0 6.6e-14 51.5 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Bromodomain PF00439.20 CBZ56330.1 - 8.4e-12 44.8 0.0 1.6e-11 43.9 0.0 1.5 1 0 0 1 1 1 1 Bromodomain HDA2-3 PF11496.3 CBZ56330.1 - 5.1e-11 41.9 0.0 1.2e-10 40.7 0.0 1.5 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.10 CBZ56330.1 - 8.4e-08 32.2 0.0 7.1e-07 29.2 0.0 2.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.24 CBZ56330.1 - 0.14 11.6 0.0 6.3 6.2 0.0 2.7 2 0 0 2 2 2 0 DEAD/DEAH box helicase DUF605 PF04652.11 CBZ56339.1 - 0.75 9.1 12.0 0.9 8.8 8.3 1.2 1 0 0 1 1 1 0 Vta1 like Neisseria_TspB PF05616.8 CBZ56345.1 - 1.4 7.1 4.9 2.1 6.6 3.4 1.2 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein ASFV_J13L PF05568.6 CBZ56346.1 - 1.6 8.2 6.3 8.2 5.9 0.3 3.0 3 0 0 3 3 3 0 African swine fever virus J13L protein WD40 PF00400.27 CBZ56349.1 - 2.2e-13 49.5 3.8 1e-05 25.1 0.1 5.6 5 1 0 5 5 5 3 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 CBZ56349.1 - 1.3e-12 47.3 0.1 2.1e-11 43.5 0.1 2.4 1 1 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex Nop10p PF04135.7 CBZ56350.1 - 1e-20 73.2 0.8 1.3e-20 72.8 0.5 1.2 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family PAP_assoc PF03828.14 CBZ56351.1 - 1.1e-06 28.5 0.1 0.00083 19.2 0.1 2.5 2 0 0 2 2 2 2 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 CBZ56351.1 - 0.022 15.0 0.0 0.047 14.0 0.0 1.5 1 0 0 1 1 1 0 Nucleotidyltransferase domain OAS1_C PF10421.4 CBZ56351.1 - 0.19 11.1 0.1 0.36 10.3 0.1 1.3 1 0 0 1 1 1 0 2'-5'-oligoadenylate synthetase 1, domain 2, C-terminus zf-RanBP PF00641.13 CBZ56353.1 - 6.5e-06 25.1 4.5 6.5e-06 25.1 3.1 2.3 3 0 0 3 3 3 1 Zn-finger in Ran binding protein and others Prenyltrans PF00432.16 CBZ56354.1 - 2.9e-28 97.1 13.8 3.8e-11 42.3 1.1 6.9 7 0 0 7 7 7 6 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 CBZ56354.1 - 4.2e-18 65.8 0.0 9.6e-13 48.5 0.0 3.7 3 1 1 4 4 4 3 Prenyltransferase-like Prenyltrans_1 PF13243.1 CBZ56354.1 - 0.0038 17.2 0.0 0.34 10.9 0.0 2.5 1 1 1 2 2 2 1 Prenyltransferase-like KH_1 PF00013.24 CBZ56356.1 - 0.019 14.6 0.0 0.045 13.3 0.0 1.5 1 0 0 1 1 1 0 KH domain Lact_bio_phlase PF09508.5 CBZ56356.1 - 0.22 9.1 0.0 0.32 8.6 0.0 1.1 1 0 0 1 1 1 0 Lacto-N-biose phosphorylase KH_3 PF13014.1 CBZ56356.1 - 0.36 10.5 0.0 0.97 9.1 0.0 1.7 1 0 0 1 1 1 0 KH domain IpaD PF06511.6 CBZ56356.1 - 7.6 5.4 0.1 19 4.0 0.0 1.6 1 0 0 1 1 1 0 Invasion plasmid antigen IpaD Protamine_3 PF08188.6 CBZ56357.1 - 0.047 13.6 1.7 0.047 13.6 1.2 1.9 2 0 0 2 2 2 0 Spermatozal protamine family V-SNARE PF05008.10 CBZ56359.1 - 6.6e-12 45.4 0.6 1.6e-11 44.1 0.4 1.7 1 0 0 1 1 1 1 Vesicle transport v-SNARE protein N-terminus V-SNARE_C PF12352.3 CBZ56359.1 - 4e-05 23.6 1.0 0.00011 22.1 0.2 2.0 1 1 1 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus MscS_porin PF12795.2 CBZ56359.1 - 0.21 10.8 0.1 0.21 10.8 0.0 2.1 3 0 0 3 3 3 0 Mechanosensitive ion channel porin domain zf-C2H2_4 PF13894.1 CBZ56360.1 - 0.82 10.1 4.9 16 6.0 0.7 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger CAP PF00188.21 CBZ56363.1 - 2e-06 28.2 6.4 6.2e-06 26.7 4.4 1.9 1 1 0 1 1 1 1 Cysteine-rich secretory protein family Glucan_synthase PF02364.10 CBZ56364.1 - 2.7e-68 230.6 16.6 6.1e-29 100.5 5.4 3.7 3 1 1 4 4 4 3 1,3-beta-glucan synthase component FKS1_dom1 PF14288.1 CBZ56364.1 - 1.7e-19 69.8 0.5 7.2e-19 67.8 0.4 2.1 1 1 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 DUF605 PF04652.11 CBZ56365.1 - 1 8.7 9.4 1.1 8.5 6.5 1.1 1 0 0 1 1 1 0 Vta1 like DUF605 PF04652.11 CBZ56366.1 - 2.4 7.4 10.3 2.9 7.1 7.1 1.1 1 0 0 1 1 1 0 Vta1 like Dicty_REP PF05086.7 CBZ56367.1 - 1.5 6.4 2.9 1.9 6.1 2.0 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF605 PF04652.11 CBZ56368.1 - 1.9 7.7 11.1 2.2 7.5 7.7 1.1 1 0 0 1 1 1 0 Vta1 like CAP_N PF01213.14 CBZ56369.1 - 0.07 12.4 4.0 0.1 11.8 2.7 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal CAP_N PF01213.14 CBZ56370.1 - 0.071 12.3 4.0 0.1 11.8 2.7 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal CAP_N PF01213.14 CBZ56371.1 - 0.064 12.5 2.6 0.088 12.0 1.8 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal CAP_N PF01213.14 CBZ56372.1 - 0.011 15.0 2.8 0.019 14.2 1.9 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal DUF605 PF04652.11 CBZ56372.1 - 0.7 9.2 12.8 0.83 8.9 8.9 1.1 1 0 0 1 1 1 0 Vta1 like Mre11_DNA_bind PF04152.9 CBZ56373.1 - 6e-30 104.3 0.1 2.5e-25 89.3 0.0 2.7 2 1 0 2 2 2 2 Mre11 DNA-binding presumed domain Metallophos PF00149.23 CBZ56373.1 - 6.3e-23 81.2 0.2 1e-22 80.5 0.2 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 CBZ56373.1 - 0.0001 22.1 0.2 0.00072 19.4 0.2 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Proteasome PF00227.21 CBZ56374.1 - 9.6e-53 178.2 0.0 1.2e-52 178.0 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 CBZ56374.1 - 6.9e-14 50.8 0.5 1.5e-13 49.7 0.0 1.8 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature G-patch PF01585.18 CBZ56375.1 - 6.6e-12 45.0 1.7 8.5e-12 44.6 0.1 2.1 2 0 0 2 2 2 1 G-patch domain G-patch_2 PF12656.2 CBZ56375.1 - 1.5e-10 40.7 0.1 1.5e-10 40.7 0.1 4.5 3 1 1 4 4 4 1 DExH-box splicing factor binding site CDC27 PF09507.5 CBZ56375.1 - 0.1 11.8 43.7 0.12 11.5 30.3 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 PAS_3 PF08447.6 CBZ56376.1 - 0.018 15.1 0.1 0.9 9.6 0.0 2.6 2 0 0 2 2 2 0 PAS fold PAS_9 PF13426.1 CBZ56376.1 - 0.024 15.0 0.0 0.081 13.3 0.0 1.9 2 0 0 2 2 2 0 PAS domain LRR_4 PF12799.2 CBZ56377.1 - 1.2e-12 47.1 5.4 2e-05 24.1 0.8 3.5 3 0 0 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CBZ56377.1 - 6.5e-06 25.8 9.6 0.0075 16.0 4.0 3.0 1 1 2 3 3 3 3 Leucine rich repeat LRR_1 PF00560.28 CBZ56377.1 - 6.1 7.2 14.9 6.1 7.2 0.6 4.8 6 0 0 6 6 6 0 Leucine Rich Repeat OTU PF02338.14 CBZ56378.1 - 2e-09 38.0 0.0 4.8e-09 36.8 0.0 1.6 1 0 0 1 1 1 1 OTU-like cysteine protease zf-C2H2_2 PF12756.2 CBZ56378.1 - 0.014 15.5 0.2 0.024 14.7 0.1 1.4 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) Dynein_light PF01221.13 CBZ56379.1 - 8.9e-25 86.5 0.1 1.1e-24 86.2 0.1 1.1 1 0 0 1 1 1 1 Dynein light chain type 1 Phi-29_GP4 PF05464.6 CBZ56379.1 - 0.024 14.5 0.0 0.03 14.2 0.0 1.2 1 0 0 1 1 1 0 Phi-29-like late genes activator (early protein GP4) Ground-like PF04155.13 CBZ56379.1 - 0.037 14.3 0.0 0.038 14.3 0.0 1.3 1 1 0 1 1 1 0 Ground-like domain Methyltransf_31 PF13847.1 CBZ56379.1 - 0.068 12.7 0.0 0.096 12.2 0.0 1.3 1 1 0 1 1 1 0 Methyltransferase domain Glycos_transf_2 PF00535.21 CBZ56380.1 - 6.9e-32 110.4 0.0 8.2e-32 110.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 CBZ56380.1 - 5.9e-12 45.8 0.0 1.6e-11 44.4 0.0 1.6 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.4 CBZ56380.1 - 4.5e-07 29.2 0.0 6.1e-07 28.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 CBZ56380.1 - 3.6e-05 23.1 0.0 5.8e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_trans_2_3 PF13632.1 CBZ56380.1 - 0.023 14.3 0.0 0.034 13.8 0.0 1.2 1 0 0 1 1 1 0 Glycosyl transferase family group 2 Lipase_3 PF01764.20 CBZ56381.1 - 6.4e-16 58.2 0.0 9.9e-16 57.6 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.2 CBZ56381.1 - 0.034 13.9 0.0 0.58 9.8 0.0 2.3 2 0 0 2 2 2 0 Alpha/beta hydrolase family TSC22 PF01166.13 CBZ56383.1 - 0.02 14.8 0.6 0.02 14.8 0.4 4.0 5 0 0 5 5 5 0 TSC-22/dip/bun family PQQ_3 PF13570.1 CBZ56383.1 - 0.13 12.5 0.9 33 4.9 0.1 3.7 3 0 0 3 3 3 0 PQQ-like domain NDUFA12 PF05071.11 CBZ56383.1 - 0.14 12.6 2.1 0.49 10.8 1.5 1.9 1 0 0 1 1 1 0 NADH ubiquinone oxidoreductase subunit NDUFA12 CLIP PF12032.3 CBZ56384.1 - 0.082 13.0 0.0 0.11 12.5 0.0 1.3 1 1 0 1 1 1 0 Regulatory CLIP domain of proteinases TSP_1 PF00090.14 CBZ56385.1 - 0.00051 20.1 7.4 0.00051 20.1 5.1 3.1 2 1 0 2 2 2 1 Thrombospondin type 1 domain DUF605 PF04652.11 CBZ56385.1 - 0.0085 15.5 12.9 0.012 14.9 9.0 1.4 1 0 0 1 1 1 1 Vta1 like CytochromB561_N PF09786.4 CBZ56385.1 - 2.3 6.5 16.6 3.6 5.9 11.5 1.2 1 0 0 1 1 1 0 Cytochrome B561, N terminal Hid1 PF12722.2 CBZ56385.1 - 4.2 4.9 9.4 6 4.4 6.5 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Spore_coat_CotO PF14153.1 CBZ56386.1 - 0.13 11.7 17.5 0.15 11.4 12.1 1.3 1 0 0 1 1 1 0 Spore coat protein CotO CDC45 PF02724.9 CBZ56386.1 - 0.27 9.2 25.3 0.31 9.0 17.5 1.1 1 0 0 1 1 1 0 CDC45-like protein eIF-3c_N PF05470.7 CBZ56386.1 - 1.4 6.9 17.7 1.5 6.8 12.2 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Nop14 PF04147.7 CBZ56386.1 - 1.6 6.5 41.0 1.7 6.4 28.4 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.7 CBZ56386.1 - 2.4 7.3 39.3 2.9 7.0 27.2 1.4 1 0 0 1 1 1 0 SDA1 Pilt PF15453.1 CBZ56386.1 - 3.8 7.0 13.0 4 7.0 9.0 1.2 1 0 0 1 1 1 0 Protein incorporated later into Tight Junctions DUF4045 PF13254.1 CBZ56386.1 - 6.9 5.8 10.1 7.6 5.6 7.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) DUF1510 PF07423.6 CBZ56386.1 - 7.5 5.8 32.1 10 5.3 22.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) CENP-T PF15511.1 CBZ56386.1 - 8.6 5.4 26.8 11 5.0 18.6 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T UCH PF00443.24 CBZ56387.1 - 1.9e-31 109.1 0.0 3.6e-31 108.2 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CBZ56387.1 - 4.5e-10 39.4 0.0 2.5e-09 36.9 0.0 2.3 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UPF0020 PF01170.13 CBZ56390.1 - 1.1e-14 54.4 0.0 4.5e-09 36.1 0.0 2.3 2 0 0 2 2 2 2 Putative RNA methylase family UPF0020 Methyltransf_26 PF13659.1 CBZ56390.1 - 6.4e-11 42.3 0.0 1.3e-10 41.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain N6_N4_Mtase PF01555.13 CBZ56390.1 - 0.00051 19.6 0.0 0.00051 19.6 0.0 4.9 3 1 0 3 3 3 2 DNA methylase Trypsin_2 PF13365.1 CBZ56391.1 - 2.6e-13 50.0 1.2 3.9e-13 49.4 0.1 1.9 2 0 0 2 2 2 1 Trypsin-like peptidase domain Trypsin PF00089.21 CBZ56391.1 - 5.1e-13 49.1 0.4 8.9e-13 48.3 0.3 1.3 1 0 0 1 1 1 1 Trypsin PDZ_2 PF13180.1 CBZ56391.1 - 9.4e-07 28.6 0.0 1.5e-05 24.7 0.0 2.5 2 0 0 2 2 2 1 PDZ domain PDZ PF00595.19 CBZ56391.1 - 0.00016 21.7 0.1 0.00049 20.2 0.0 1.8 2 0 0 2 2 2 1 PDZ domain (Also known as DHR or GLGF) Peptidase_S7 PF00949.16 CBZ56391.1 - 0.0031 16.8 0.0 0.0072 15.7 0.0 1.5 1 0 0 1 1 1 1 Peptidase S7, Flavivirus NS3 serine protease Ras PF00071.17 CBZ56392.1 - 7e-09 35.2 0.5 0.00071 18.9 0.2 3.2 2 1 0 2 2 2 2 Ras family Miro PF08477.8 CBZ56392.1 - 1.7e-06 28.4 0.0 0.05 14.0 0.0 2.5 3 0 0 3 3 3 2 Miro-like protein Dynamin_N PF00350.18 CBZ56392.1 - 0.0039 17.0 0.0 0.0084 15.9 0.0 1.5 1 0 0 1 1 1 1 Dynamin family Gtr1_RagA PF04670.7 CBZ56392.1 - 0.044 12.9 0.0 2.7 7.0 0.0 2.1 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region AAA_28 PF13521.1 CBZ56392.1 - 0.096 12.6 0.1 0.56 10.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain Abhydrolase_6 PF12697.2 CBZ56393.1 - 2.2e-08 34.2 13.5 3.3e-07 30.4 9.4 2.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CBZ56393.1 - 0.00044 20.0 0.0 0.019 14.6 0.0 2.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CBZ56393.1 - 0.00068 19.2 0.0 0.0012 18.5 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold OmpH PF03938.9 CBZ56394.1 - 0.0085 16.0 2.0 0.011 15.7 1.4 1.3 1 0 0 1 1 1 1 Outer membrane protein (OmpH-like) SecA_SW PF07516.8 CBZ56394.1 - 0.01 15.6 4.7 0.014 15.1 3.3 1.2 1 0 0 1 1 1 0 SecA Wing and Scaffold domain Lipoprotein_20 PF13942.1 CBZ56394.1 - 0.025 14.1 1.3 0.025 14.1 0.9 1.5 2 0 0 2 2 2 0 YfhG lipoprotein IncA PF04156.9 CBZ56394.1 - 0.036 13.6 2.4 0.047 13.2 1.7 1.2 1 0 0 1 1 1 0 IncA protein DUF932 PF06067.6 CBZ56394.1 - 0.075 12.3 2.4 0.1 11.8 1.3 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF932) Atg14 PF10186.4 CBZ56394.1 - 0.71 8.7 6.1 0.78 8.6 4.2 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 CorA PF01544.13 CBZ56394.1 - 5.9 5.8 6.5 14 4.5 4.5 1.6 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein DUF547 PF04784.9 CBZ56395.1 - 1.7e-22 79.4 0.0 2.9e-22 78.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF547 DEP PF00610.16 CBZ56395.1 - 2.9e-11 42.9 0.0 7e-11 41.7 0.0 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Glutaredoxin PF00462.19 CBZ56395.1 - 0.0011 18.8 0.0 0.034 14.1 0.0 2.5 2 0 0 2 2 2 1 Glutaredoxin HeH PF12949.2 CBZ56395.1 - 0.058 12.9 0.1 0.31 10.6 0.0 2.2 2 0 0 2 2 2 0 HeH/LEM domain PWWP PF00855.12 CBZ56396.1 - 2.3e-10 40.5 0.0 2.3e-09 37.3 0.0 2.8 1 0 0 1 1 1 1 PWWP domain DUF2009 PF09418.5 CBZ56397.1 - 3.5e-181 602.9 1.0 4.6e-126 421.2 0.0 3.1 2 1 1 3 3 3 3 Protein of unknown function (DUF2009) GDA1_CD39 PF01150.12 CBZ56399.1 - 1.1e-56 192.2 0.0 1.5e-56 191.7 0.0 1.1 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family DUF972 PF06156.8 CBZ56400.1 - 0.7 10.2 5.2 0.17 12.2 0.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF972) UPF0242 PF06785.6 CBZ56400.1 - 7.6 5.0 5.9 13 4.3 4.1 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) Ribosomal_S14 PF00253.16 CBZ56401.1 - 0.011 15.0 2.5 0.013 14.8 0.8 1.8 2 0 0 2 2 2 0 Ribosomal protein S14p/S29e DUF1279 PF06916.8 CBZ56402.1 - 3e-12 46.6 0.0 7.4e-12 45.4 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1279) PRCC PF10253.4 CBZ56402.1 - 0.2 12.3 8.1 0.48 11.1 5.6 1.7 1 1 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting zf-HIT PF04438.11 CBZ56403.1 - 0.14 11.7 19.1 1.3 8.6 13.2 2.1 1 1 0 1 1 1 0 HIT zinc finger Sec62 PF03839.11 CBZ56403.1 - 0.76 9.1 5.0 0.99 8.7 3.5 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 YEATS PF03366.11 CBZ56405.1 - 0.23 11.1 17.1 27 4.5 0.0 7.6 5 3 2 8 8 8 0 YEATS family PIG-U PF06728.8 CBZ56406.1 - 4.7e-66 223.2 5.3 1.8e-64 217.9 3.7 2.0 1 1 0 1 1 1 1 GPI transamidase subunit PIG-U Fiji_64_capsid PF05880.6 CBZ56407.1 - 5.2 5.2 0.0 7.6 4.7 0.0 1.1 1 0 0 1 1 1 0 Fijivirus 64 kDa capsid protein UvrD-helicase PF00580.16 CBZ56408.1 - 3.3e-40 138.3 1.0 1e-15 57.8 0.0 3.8 4 1 0 4 4 4 3 UvrD/REP helicase N-terminal domain AAA_19 PF13245.1 CBZ56408.1 - 5.5e-12 45.2 2.2 4.5e-11 42.3 0.2 2.8 2 0 0 2 2 2 1 Part of AAA domain AAA_11 PF13086.1 CBZ56408.1 - 0.0076 15.8 0.1 0.032 13.8 0.0 2.1 2 1 0 2 2 2 1 AAA domain CobA_CobO_BtuR PF02572.10 CBZ56408.1 - 0.082 12.5 0.0 2.7 7.5 0.0 2.3 2 0 0 2 2 2 0 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP DEAD PF00270.24 CBZ56408.1 - 0.14 11.6 0.0 0.26 10.7 0.0 1.4 1 0 0 1 1 1 0 DEAD/DEAH box helicase CENP-T PF15511.1 CBZ56409.1 - 0.51 9.5 35.7 0.65 9.1 24.7 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T DUF4045 PF13254.1 CBZ56409.1 - 1.5 7.9 18.1 2.1 7.5 12.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) UvrD_C PF13361.1 CBZ56410.1 - 1.8e-25 90.1 0.0 6.1e-21 75.2 0.0 2.6 2 1 0 2 2 2 2 UvrD-like helicase C-terminal domain UvrD_C_2 PF13538.1 CBZ56410.1 - 2.8e-09 37.0 0.0 0.00038 20.5 0.0 2.8 2 0 0 2 2 2 2 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.13 CBZ56410.1 - 0.066 12.7 0.0 3.2 7.1 0.1 2.3 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_12 PF13087.1 CBZ56410.1 - 0.069 12.5 0.0 0.26 10.6 0.0 2.0 1 1 0 1 1 1 0 AAA domain Slx4 PF09494.5 CBZ56411.1 - 2.4e-10 40.0 0.0 4e-10 39.2 0.0 1.4 1 0 0 1 1 1 1 Slx4 endonuclease Topoisom_bac PF01131.15 CBZ56412.1 - 5e-72 242.9 0.0 1.3e-33 116.4 0.2 5.5 4 1 1 5 5 5 4 DNA topoisomerase Toprim PF01751.17 CBZ56412.1 - 1.1e-13 51.0 0.0 2.9e-13 49.6 0.0 1.7 1 0 0 1 1 1 1 Toprim domain zf-C4_Topoisom PF01396.14 CBZ56412.1 - 4.1e-09 35.7 1.2 7.6e-09 34.9 0.8 1.4 1 0 0 1 1 1 1 Topoisomerase DNA binding C4 zinc finger WD40 PF00400.27 CBZ56413.1 - 1e-13 50.5 8.9 1.6e-05 24.6 0.1 5.6 7 0 0 7 7 7 4 WD domain, G-beta repeat Metal_resist PF13801.1 CBZ56413.1 - 0.083 12.8 5.8 0.28 11.1 4.0 1.9 1 0 0 1 1 1 0 Heavy-metal resistance AAA PF00004.24 CBZ56414.1 - 1.9e-40 138.1 0.0 4.5e-40 136.9 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 CBZ56414.1 - 1.1e-06 28.7 0.1 0.0001 22.4 0.0 2.7 2 1 0 2 2 1 1 AAA domain AAA_5 PF07728.9 CBZ56414.1 - 1.6e-05 24.6 0.1 9.2e-05 22.1 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 CBZ56414.1 - 0.0002 22.1 0.1 0.00049 20.8 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 CBZ56414.1 - 0.00025 21.1 0.0 0.00057 19.9 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.1 CBZ56414.1 - 0.0012 18.5 0.1 0.0028 17.3 0.1 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_2 PF07724.9 CBZ56414.1 - 0.0017 18.2 0.0 0.0043 16.9 0.0 1.7 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.7 CBZ56414.1 - 0.002 17.2 0.0 0.0054 15.7 0.0 1.6 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_33 PF13671.1 CBZ56414.1 - 0.012 15.4 0.0 0.026 14.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 CBZ56414.1 - 0.016 15.2 0.0 0.027 14.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 CBZ56414.1 - 0.02 15.1 0.0 0.046 14.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 CBZ56414.1 - 0.027 13.5 0.0 0.048 12.7 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin DUF815 PF05673.8 CBZ56414.1 - 0.037 12.9 0.0 0.057 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_24 PF13479.1 CBZ56414.1 - 0.047 13.2 0.1 0.1 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 CBZ56414.1 - 0.058 12.8 0.0 0.093 12.1 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein Mg_chelatase PF01078.16 CBZ56414.1 - 0.064 12.4 0.0 0.14 11.3 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_14 PF13173.1 CBZ56414.1 - 0.066 13.1 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.8 CBZ56414.1 - 0.078 11.6 0.0 0.13 10.9 0.0 1.3 1 0 0 1 1 1 0 TIP49 C-terminus T2SE PF00437.15 CBZ56414.1 - 0.091 11.6 0.0 0.22 10.4 0.0 1.4 1 1 0 1 1 1 0 Type II/IV secretion system protein RNA_helicase PF00910.17 CBZ56414.1 - 0.1 12.7 0.0 0.22 11.7 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_11 PF13086.1 CBZ56414.1 - 0.13 11.8 0.0 0.21 11.1 0.0 1.4 1 1 0 1 1 1 0 AAA domain ST7 PF04184.7 CBZ56415.1 - 2.9 6.0 1.9 4.6 5.3 1.3 1.2 1 0 0 1 1 1 0 ST7 protein GDA1_CD39 PF01150.12 CBZ56416.1 - 8.8e-101 337.5 0.0 1.1e-100 337.1 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Rad21_Rec8 PF04824.11 CBZ56417.1 - 0.0023 17.0 0.0 0.0055 15.8 0.0 1.6 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein Rad21_Rec8_N PF04825.8 CBZ56417.1 - 0.061 13.2 0.0 0.15 11.9 0.0 1.6 1 0 0 1 1 1 0 N terminus of Rad21 / Rec8 like protein Clathrin PF00637.15 CBZ56419.1 - 5.8e-06 25.9 0.0 0.004 16.7 0.0 2.5 3 0 0 3 3 3 2 Region in Clathrin and VPS CPSF_A PF03178.10 CBZ56420.1 - 5.1e-19 68.5 0.0 7.6e-19 67.9 0.0 1.2 1 0 0 1 1 1 1 CPSF A subunit region zf-DHHC PF01529.15 CBZ56421.1 - 8.1e-35 119.7 11.7 1.9e-34 118.5 8.1 1.6 1 1 0 1 1 1 1 DHHC palmitoyltransferase Imm10 PF15562.1 CBZ56421.1 - 0.031 14.0 0.1 0.087 12.5 0.0 1.7 1 0 0 1 1 1 0 Immunity protein 10 GDA1_CD39 PF01150.12 CBZ56422.1 - 3.8e-181 602.3 0.0 7.7e-100 334.4 0.0 2.0 2 0 0 2 2 2 2 GDA1/CD39 (nucleoside phosphatase) family Na_H_antiporter PF03553.9 CBZ56422.1 - 0.00049 19.2 0.0 0.83 8.6 0.0 2.3 2 0 0 2 2 2 2 Na+/H+ antiporter family Sensor PF13796.1 CBZ56422.1 - 0.15 11.6 0.0 22 4.6 0.0 2.3 2 0 0 2 2 2 0 Putative sensor Rad21_Rec8 PF04824.11 CBZ56423.1 - 0.0021 17.2 0.0 0.0047 16.0 0.0 1.5 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein AAA_25 PF13481.1 CBZ56425.1 - 1.5e-09 37.5 0.0 3e-06 26.7 0.0 3.2 3 0 0 3 3 3 1 AAA domain Rad51 PF08423.6 CBZ56425.1 - 3.7e-06 26.0 0.0 0.008 15.1 0.0 3.3 3 0 0 3 3 3 2 Rad51 KaiC PF06745.8 CBZ56425.1 - 0.00074 18.6 0.0 0.0016 17.5 0.0 1.5 1 0 0 1 1 1 1 KaiC AAA_22 PF13401.1 CBZ56425.1 - 0.001 19.1 0.0 0.004 17.3 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 CBZ56425.1 - 0.0031 17.2 0.3 0.016 14.9 0.0 2.4 2 1 0 2 2 2 1 Part of AAA domain AAA PF00004.24 CBZ56425.1 - 0.017 15.2 0.1 0.058 13.6 0.0 1.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 CBZ56425.1 - 0.026 15.3 1.1 0.054 14.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain HTH_20 PF12840.2 CBZ56425.1 - 0.033 13.9 0.1 0.1 12.3 0.0 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain AAA_33 PF13671.1 CBZ56425.1 - 0.04 13.7 0.4 0.17 11.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.1 CBZ56425.1 - 0.065 12.8 0.0 0.49 9.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain MobB PF03205.9 CBZ56425.1 - 0.11 12.2 0.0 1.1 8.9 0.0 2.1 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B RNA_helicase PF00910.17 CBZ56425.1 - 0.23 11.6 0.0 0.46 10.6 0.0 1.4 1 0 0 1 1 1 0 RNA helicase XPG_N PF00752.12 CBZ56426.1 - 9.6e-14 51.4 0.0 4.1e-07 30.1 0.0 2.5 2 0 0 2 2 2 2 XPG N-terminal domain XPG_I PF00867.13 CBZ56426.1 - 1.5e-13 50.6 0.3 3.4e-13 49.4 0.2 1.6 1 0 0 1 1 1 1 XPG I-region XPG_I_2 PF12813.2 CBZ56426.1 - 0.00069 19.1 0.2 0.0013 18.3 0.1 1.3 1 0 0 1 1 1 1 XPG domain containing Mito_carr PF00153.22 CBZ56427.1 - 2.4e-56 187.4 1.2 9.9e-21 73.2 0.0 5.0 4 1 0 4 4 4 4 Mitochondrial carrier protein FLYWCH_N PF15423.1 CBZ56428.1 - 0.016 15.3 0.3 0.026 14.7 0.2 1.4 1 0 0 1 1 1 0 FLYWCH-type zinc finger-containing protein NESP55 PF06390.7 CBZ56428.1 - 0.032 13.6 1.2 0.039 13.3 0.9 1.1 1 0 0 1 1 1 0 Neuroendocrine-specific golgi protein P55 (NESP55) SNF2_N PF00176.18 CBZ56429.1 - 2.6e-27 95.4 0.1 1e-25 90.2 0.1 2.1 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 CBZ56429.1 - 3.7e-05 23.5 0.0 0.00041 20.1 0.0 2.4 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 CBZ56429.1 - 0.00032 20.5 0.0 1.9 8.2 0.0 3.2 3 0 0 3 3 3 2 Type III restriction enzyme, res subunit CobT PF06213.7 CBZ56430.1 - 0.05 12.7 32.1 0.0054 15.9 17.0 2.5 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT Astro_capsid PF03115.9 CBZ56430.1 - 2.6 6.1 9.0 4.1 5.5 6.3 1.2 1 0 0 1 1 1 0 Astrovirus capsid protein precursor Hid1 PF12722.2 CBZ56430.1 - 3 5.4 8.9 5.7 4.4 6.2 1.4 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SPRY PF00622.23 CBZ56431.1 - 0.003 17.6 0.7 0.18 11.9 0.1 2.6 2 0 0 2 2 2 2 SPRY domain tRNA-synt_1 PF00133.17 CBZ56432.1 - 1.6e-100 336.8 0.0 4.8e-41 140.4 0.0 8.2 7 1 0 7 7 7 7 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 CBZ56432.1 - 3.7e-22 78.7 0.0 6.8e-22 77.8 0.0 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 CBZ56432.1 - 1e-12 47.4 0.0 2.2e-06 26.6 0.0 4.0 3 1 0 4 4 4 3 tRNA synthetases class I (M) SufE PF02657.10 CBZ56433.1 - 7.3e-22 77.3 0.0 9.8e-22 76.9 0.0 1.1 1 0 0 1 1 1 1 Fe-S metabolism associated domain Sec23_trunk PF04811.10 CBZ56434.1 - 3.2e-19 69.2 0.0 3e-12 46.4 0.0 2.3 2 0 0 2 2 2 2 Sec23/Sec24 trunk domain Sec23_BS PF08033.7 CBZ56434.1 - 4.2e-16 59.2 0.0 8.9e-16 58.1 0.0 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Sec23_helical PF04815.10 CBZ56434.1 - 2.3e-11 43.0 0.3 1e-09 37.7 0.0 2.7 2 1 0 2 2 2 1 Sec23/Sec24 helical domain Gelsolin PF00626.17 CBZ56434.1 - 0.00021 20.8 0.0 0.00054 19.6 0.0 1.7 1 0 0 1 1 1 1 Gelsolin repeat TPR_11 PF13414.1 CBZ56436.1 - 4.3e-11 42.3 3.5 7.5e-07 28.7 0.1 2.9 1 1 1 2 2 2 2 TPR repeat TPR_2 PF07719.12 CBZ56436.1 - 1.5e-07 30.7 6.5 0.0015 18.3 0.4 4.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 CBZ56436.1 - 1.2e-06 27.8 2.8 0.14 11.8 0.0 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 CBZ56436.1 - 0.00041 20.9 2.2 0.99 10.1 0.0 3.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 CBZ56436.1 - 0.0045 17.5 11.6 0.16 12.6 1.8 4.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.1 CBZ56436.1 - 0.021 14.6 8.5 0.028 14.2 1.9 3.5 2 0 0 2 2 2 0 Tetratricopeptide repeat Bact_transglu_N PF08379.5 CBZ56436.1 - 0.021 15.1 0.0 0.051 13.8 0.0 1.6 1 0 0 1 1 1 0 Bacterial transglutaminase-like N-terminal region Apc5 PF12862.2 CBZ56436.1 - 0.081 12.7 0.2 0.32 10.8 0.0 2.1 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 5 F-box-like PF12937.2 CBZ56437.1 - 0.0036 16.9 0.2 0.011 15.4 0.0 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 CBZ56437.1 - 0.031 13.9 0.0 0.1 12.3 0.0 1.8 1 0 0 1 1 1 0 F-box domain RAMP4 PF06624.7 CBZ56438.1 - 3.7e-24 84.0 0.1 4e-24 83.9 0.1 1.0 1 0 0 1 1 1 1 Ribosome associated membrane protein RAMP4 PP2C PF00481.16 CBZ56440.1 - 6.6e-26 91.2 0.0 9.7e-26 90.6 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 CBZ56440.1 - 0.066 12.9 0.0 0.18 11.5 0.0 1.7 1 1 0 1 1 1 0 Stage II sporulation protein E (SpoIIE) PGA2 PF07543.7 CBZ56440.1 - 4 7.2 5.9 11 5.8 4.1 1.7 1 0 0 1 1 1 0 Protein trafficking PGA2 ER_lumen_recept PF00810.13 CBZ56441.1 - 2.7e-49 167.4 10.8 4.3e-49 166.7 7.5 1.3 1 0 0 1 1 1 1 ER lumen protein retaining receptor PQ-loop PF04193.9 CBZ56441.1 - 0.0053 16.2 7.3 0.27 10.8 0.1 3.7 3 1 1 4 4 4 2 PQ loop repeat DUF3021 PF11457.3 CBZ56441.1 - 0.17 11.7 7.8 0.066 13.0 3.1 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3021) Mito_carr PF00153.22 CBZ56442.1 - 0.027 14.1 0.0 0.097 12.3 0.0 1.9 1 1 0 1 1 1 0 Mitochondrial carrier protein YtxH PF12732.2 CBZ56444.1 - 0.00035 20.8 12.6 0.084 13.2 0.5 3.1 1 1 2 3 3 3 3 YtxH-like protein DUF883 PF05957.8 CBZ56444.1 - 0.00043 20.6 11.9 0.16 12.3 0.4 2.5 1 1 1 2 2 2 2 Bacterial protein of unknown function (DUF883) CAP18_C PF12153.3 CBZ56444.1 - 0.0023 17.5 0.2 9.1 6.0 0.4 3.3 3 0 0 3 3 3 2 LPS binding domain of CAP18 (C terminal) Chlorosome_CsmC PF11098.3 CBZ56444.1 - 0.082 12.6 11.1 0.6 9.8 0.4 2.2 1 1 1 2 2 2 0 Chlorosome envelope protein C LEA_4 PF02987.11 CBZ56444.1 - 0.12 12.2 24.3 0.2 11.5 1.4 4.0 2 2 1 3 3 3 0 Late embryogenesis abundant protein Tape_meas_lam_C PF09718.5 CBZ56444.1 - 0.19 11.6 20.2 0.84 9.5 0.6 4.0 1 1 3 4 4 4 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) ATP-synt_B PF00430.13 CBZ56444.1 - 1.4 8.7 10.3 0.22 11.3 0.3 2.1 1 1 1 2 2 2 0 ATP synthase B/B' CF(0) Phasin_2 PF09361.5 CBZ56444.1 - 1.4 8.9 9.9 0.4 10.7 3.7 2.1 1 1 1 2 2 2 0 Phasin protein GTSE1_N PF15259.1 CBZ56445.1 - 0.6 10.0 4.7 0.41 10.5 0.5 2.0 1 1 1 2 2 2 0 G-2 and S-phase expressed 1 DUF883 PF05957.8 CBZ56445.1 - 5 7.6 13.7 19 5.7 1.6 3.4 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF883) Apolipoprotein PF01442.13 CBZ56446.1 - 1.3e-07 31.3 9.5 0.0081 15.6 0.5 3.7 1 1 1 2 2 2 2 Apolipoprotein A1/A4/E domain DUF883 PF05957.8 CBZ56446.1 - 3.4e-06 27.3 63.7 0.042 14.2 2.6 8.2 1 1 7 8 8 8 5 Bacterial protein of unknown function (DUF883) Tmemb_cc2 PF10267.4 CBZ56446.1 - 0.0025 16.4 12.5 0.0025 16.4 8.6 2.7 2 2 0 2 2 2 2 Predicted transmembrane and coiled-coil 2 protein ApoLp-III PF07464.6 CBZ56446.1 - 0.041 13.9 35.0 0.13 12.3 4.5 4.4 2 2 3 5 5 5 0 Apolipophorin-III precursor (apoLp-III) YtxH PF12732.2 CBZ56446.1 - 0.18 12.2 72.1 13 6.2 3.8 9.4 1 1 2 3 3 3 0 YtxH-like protein DUF883 PF05957.8 CBZ56447.1 - 0.0029 17.9 10.9 0.048 14.0 1.4 2.0 1 1 1 2 2 2 2 Bacterial protein of unknown function (DUF883) Apo-CII PF05355.6 CBZ56447.1 - 0.036 13.9 1.1 0.049 13.5 0.1 1.7 2 0 0 2 2 2 0 Apolipoprotein C-II Hemerythrin PF01814.18 CBZ56447.1 - 0.053 13.6 0.9 0.097 12.8 0.1 1.6 1 1 1 2 2 2 0 Hemerythrin HHE cation binding domain MAD PF05557.8 CBZ56447.1 - 0.26 9.3 3.1 0.27 9.2 2.2 1.0 1 0 0 1 1 1 0 Mitotic checkpoint protein Tape_meas_lam_C PF09718.5 CBZ56447.1 - 0.3 11.0 6.5 3.4 7.6 0.3 2.1 1 1 1 2 2 2 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) YtxH PF12732.2 CBZ56447.1 - 0.36 11.2 8.7 43 4.5 6.0 2.1 1 1 0 1 1 1 0 YtxH-like protein Senescence PF06911.7 CBZ56447.1 - 0.61 9.7 7.7 0.77 9.4 5.3 1.1 1 0 0 1 1 1 0 Senescence-associated protein HisKA_3 PF07730.8 CBZ56447.1 - 0.85 10.0 3.6 22 5.4 2.5 2.1 1 1 0 1 1 1 0 Histidine kinase LEA_4 PF02987.11 CBZ56447.1 - 2.2 8.2 11.9 0.088 12.6 1.5 2.5 2 1 0 2 2 2 0 Late embryogenesis abundant protein Chlorosome_CsmC PF11098.3 CBZ56447.1 - 2.6 7.7 6.1 4.8 6.8 0.7 2.0 1 1 1 2 2 2 0 Chlorosome envelope protein C GvpO PF05800.6 CBZ56447.1 - 3.1 7.7 7.4 5.3 6.9 0.8 2.3 1 1 1 2 2 2 0 Gas vesicle synthesis protein GvpO ATP-synt_B PF00430.13 CBZ56447.1 - 8.8 6.1 12.6 2.5 7.9 1.9 2.0 1 1 1 2 2 2 0 ATP synthase B/B' CF(0) LRR_6 PF13516.1 CBZ56448.1 - 0.0082 16.1 3.8 0.09 12.8 0.0 3.4 4 0 0 4 4 4 1 Leucine Rich repeat