# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- OB_NTP_bind PF07717.11 CDI73657.1 - 1e-28 99.4 0.0 2.3e-28 98.2 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 CDI73657.1 - 6.3e-23 80.7 0.0 6.3e-23 80.7 0.0 2.7 2 1 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.26 CDI73657.1 - 2.1e-11 43.5 0.0 4.8e-11 42.3 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain T2SE PF00437.15 CDI73657.1 - 0.00011 21.1 0.0 0.00023 20.1 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein DEAD PF00270.24 CDI73657.1 - 0.00017 21.1 0.0 0.0004 19.9 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 CDI73657.1 - 0.00025 21.1 2.4 0.0011 19.0 0.0 3.1 3 0 0 3 3 3 1 AAA domain cobW PF02492.14 CDI73657.1 - 0.097 12.1 0.0 1.1 8.7 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ABC_tran PF00005.22 CDI73657.1 - 1.6 9.0 3.8 2.1 8.6 0.0 2.9 2 1 0 2 2 2 0 ABC transporter Med3 PF11593.3 CDI73657.1 - 2.7 7.1 10.0 4.6 6.3 6.9 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal AAA_23 PF13476.1 CDI73657.1 - 3.5 7.8 0.0 3.5 7.8 0.0 3.2 2 1 0 2 2 2 0 AAA domain Serpin PF00079.15 CDI73658.1 - 1e-77 261.7 0.0 1.2e-77 261.5 0.0 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) CHD5 PF04420.9 CDI73659.1 - 2.4e-06 27.3 3.5 3.6e-06 26.7 2.4 1.2 1 0 0 1 1 1 1 CHD5-like protein SpaB_C PF14028.1 CDI73659.1 - 0.031 13.8 0.8 0.039 13.5 0.5 1.1 1 0 0 1 1 1 0 SpaB C-terminal domain DUF4349 PF14257.1 CDI73659.1 - 0.062 12.5 4.8 0.11 11.7 3.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) Enterotoxin_HS1 PF08090.6 CDI73659.1 - 0.17 11.6 0.3 0.17 11.6 0.2 2.0 2 0 0 2 2 2 0 Heat stable E.coli enterotoxin 1 PRMT5 PF05185.11 CDI73659.1 - 0.59 8.9 3.4 0.81 8.5 2.4 1.1 1 0 0 1 1 1 0 PRMT5 arginine-N-methyltransferase DUF964 PF06133.6 CDI73659.1 - 0.9 9.5 16.8 8 6.5 11.6 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF964) dsDNA_bind PF01984.15 CDI73660.1 - 3.9e-23 81.4 11.7 4.8e-23 81.1 8.1 1.0 1 0 0 1 1 1 1 Double-stranded DNA-binding domain TrbH PF07283.6 CDI73660.1 - 0.0086 15.9 0.4 0.013 15.3 0.3 1.2 1 0 0 1 1 1 1 Conjugal transfer protein TrbH Cut8_N PF14482.1 CDI73660.1 - 0.15 12.0 5.3 3.7 7.6 0.6 2.4 2 0 0 2 2 2 0 Cut8 proteasome-binding domain RRP14 PF15459.1 CDI73660.1 - 0.25 11.4 5.0 2.3 8.3 2.0 2.2 2 0 0 2 2 2 0 60S ribosome biogenesis protein Rrp14 TPR_16 PF13432.1 CDI73660.1 - 0.4 11.4 2.5 0.61 10.8 1.7 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF1682 PF07946.9 CDI73660.1 - 1.4 7.6 8.2 1.9 7.2 5.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) DivIC PF04977.10 CDI73660.1 - 2.5 7.6 8.5 4.5 6.8 5.9 1.4 1 0 0 1 1 1 0 Septum formation initiator Serpin PF00079.15 CDI73661.1 - 9.9e-77 258.5 0.0 1.2e-76 258.3 0.0 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) Cpn60_TCP1 PF00118.19 CDI73662.1 - 2.7e-121 405.5 9.2 3.1e-121 405.3 6.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family TAXi_C PF14541.1 CDI73662.1 - 0.044 13.3 0.5 6.5 6.2 0.0 3.1 3 0 0 3 3 3 0 Xylanase inhibitor C-terminal Fis1_TPR_C PF14853.1 CDI73663.1 - 5.4e-16 58.2 0.2 1.1e-15 57.2 0.1 1.5 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat Fis1_TPR_N PF14852.1 CDI73663.1 - 5.6e-07 28.7 0.0 1.1e-06 27.7 0.0 1.6 1 0 0 1 1 1 1 Fis1 N-terminal tetratricopeptide repeat TPR_11 PF13414.1 CDI73663.1 - 0.00023 20.7 0.0 0.00045 19.8 0.0 1.5 1 0 0 1 1 1 1 TPR repeat TPR_2 PF07719.12 CDI73663.1 - 0.00044 19.9 0.3 0.0019 17.9 0.0 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 CDI73663.1 - 0.002 18.5 0.4 0.043 14.4 0.0 2.6 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 CDI73663.1 - 0.0044 17.3 0.1 0.0093 16.2 0.0 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_16 PF13432.1 CDI73663.1 - 0.0053 17.3 1.7 0.0082 16.7 0.2 2.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 CDI73663.1 - 0.03 14.2 0.1 0.064 13.2 0.1 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_6 PF13174.1 CDI73663.1 - 0.033 14.6 0.5 0.12 12.8 0.0 2.2 3 0 0 3 3 2 0 Tetratricopeptide repeat Neuropep_like PF15161.1 CDI73663.1 - 0.098 12.1 0.4 0.35 10.3 0.1 2.0 2 0 0 2 2 2 0 Neuropeptide-like UBA PF00627.26 CDI73663.1 - 0.11 12.3 0.0 0.27 11.1 0.0 1.7 1 0 0 1 1 1 0 UBA/TS-N domain TPR_1 PF00515.23 CDI73663.1 - 0.12 11.9 0.1 0.25 11.0 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF3223 PF11523.3 CDI73664.1 - 0.044 14.0 0.0 0.069 13.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3223) DNA_pol_E_B PF04042.11 CDI73666.1 - 3.6e-21 75.3 3.4 4.1e-21 75.2 0.6 2.2 3 0 0 3 3 3 1 DNA polymerase alpha/epsilon subunit B Ima1_N PF09779.4 CDI73666.1 - 0.0094 16.4 0.9 0.018 15.5 0.6 1.5 1 0 0 1 1 1 1 Ima1 N-terminal domain Ribosomal_60s PF00428.14 CDI73666.1 - 0.029 14.7 18.4 0.84 10.0 3.4 3.8 3 0 0 3 3 3 0 60s Acidic ribosomal protein C2 PF00168.25 CDI73667.1 - 8.6e-28 96.0 0.1 2.5e-07 30.4 0.0 7.0 7 0 0 7 7 7 5 C2 domain FerI PF08151.7 CDI73667.1 - 0.045 13.7 0.0 0.71 9.9 0.0 2.4 2 0 0 2 2 2 0 FerI (NUC094) domain zf-RING_2 PF13639.1 CDI73668.1 - 1.7e-13 50.1 9.1 2.7e-13 49.4 6.3 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 CDI73668.1 - 4.5e-08 33.0 3.7 7.9e-08 32.3 2.5 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 CDI73668.1 - 1.6e-06 27.6 9.1 2.4e-06 27.1 6.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 CDI73668.1 - 4.5e-06 26.4 1.7 8e-06 25.6 1.2 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.1 CDI73668.1 - 5.6e-06 25.9 4.8 8.3e-06 25.3 3.4 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CDI73668.1 - 1.6e-05 24.8 10.4 2.4e-05 24.2 7.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CDI73668.1 - 6.2e-05 22.6 7.6 9.4e-05 22.0 5.3 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-Nse PF11789.3 CDI73668.1 - 0.00069 19.0 4.5 0.0013 18.2 3.1 1.3 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit RINGv PF12906.2 CDI73668.1 - 0.013 15.4 8.7 0.025 14.6 6.0 1.5 1 0 0 1 1 1 0 RING-variant domain zf-RING_UBOX PF13445.1 CDI73668.1 - 0.017 14.8 5.7 0.033 13.9 3.9 1.5 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_4 PF15227.1 CDI73668.1 - 0.06 13.2 8.3 0.11 12.3 5.7 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING FANCL_C PF11793.3 CDI73668.1 - 0.58 10.1 8.5 2.8 7.9 5.9 2.0 1 1 0 1 1 1 0 FANCL C-terminal domain PHD PF00628.24 CDI73668.1 - 2.7 7.7 6.2 4.1 7.1 4.3 1.3 1 0 0 1 1 1 0 PHD-finger Ole-e-6 PF09253.5 CDI73669.1 - 0.14 11.7 0.2 0.31 10.7 0.1 1.5 1 0 0 1 1 1 0 Pollen allergen ole e 6 DUF342 PF03961.8 CDI73669.1 - 7.3 4.8 25.7 0.057 11.8 2.8 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF342) Phosphodiest PF01663.17 CDI73670.1 - 0.0027 17.0 0.1 0.0048 16.2 0.1 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Tub_2 PF04525.7 CDI73671.1 - 0.29 10.5 0.1 0.49 9.7 0.0 1.3 1 0 0 1 1 1 0 Tubby C 2 cNMP_binding PF00027.24 CDI73672.1 - 2e-83 274.3 4.8 3.7e-18 65.1 0.0 6.6 6 0 0 6 6 6 6 Cyclic nucleotide-binding domain EF-hand_1 PF00036.27 CDI73672.1 - 0.0036 16.5 1.0 0.2 11.0 0.1 2.8 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.1 CDI73672.1 - 0.056 13.3 0.3 0.99 9.4 0.0 2.8 2 0 0 2 2 2 0 EF-hand domain RRM_6 PF14259.1 CDI73673.1 - 2.3e-05 24.3 0.0 0.0022 17.9 0.0 3.2 3 0 0 3 3 3 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CDI73673.1 - 3.6e-05 23.3 0.0 0.31 10.6 0.0 3.7 3 1 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PRP21_like_P PF12230.3 CDI73674.1 - 4.2e-47 160.5 5.0 4.2e-47 160.5 3.5 2.0 2 0 0 2 2 2 1 Pre-mRNA splicing factor PRP21 like protein Surp PF01805.15 CDI73674.1 - 7e-34 115.2 1.5 2.4e-16 59.1 0.0 2.8 3 0 0 3 3 3 2 Surp module DUF1682 PF07946.9 CDI73674.1 - 0.00018 20.4 3.7 0.00018 20.4 2.5 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1682) EIF_2_alpha PF07541.7 CDI73674.1 - 0.017 14.7 0.1 0.039 13.6 0.1 1.5 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 2 alpha subunit PapD-like PF14874.1 CDI73676.1 - 0.0044 16.9 4.3 0.99 9.3 0.1 4.4 5 0 0 5 5 5 1 Flagellar-associated PapD-like Dpy19 PF10034.4 CDI73676.1 - 0.72 7.9 1.0 3.1 5.8 0.7 2.1 1 0 0 1 1 1 0 Q-cell neuroblast polarisation PMSR PF01625.16 CDI73677.1 - 0.0073 16.2 1.9 0.011 15.6 1.3 1.2 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase Spc7_N PF15402.1 CDI73677.1 - 0.63 7.9 14.2 0.8 7.6 9.9 1.1 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 CBP4 PF07960.6 CDI73677.1 - 1.8 8.1 12.9 3 7.4 8.9 1.3 1 0 0 1 1 1 0 CBP4 Arm PF00514.18 CDI73678.1 - 0.0011 18.6 3.7 0.42 10.5 0.1 4.0 3 0 0 3 3 3 2 Armadillo/beta-catenin-like repeat SurE PF01975.12 CDI73678.1 - 0.016 14.5 0.9 0.016 14.5 0.6 2.5 2 0 0 2 2 2 0 Survival protein SurE Acetyltransf_3 PF13302.1 CDI73678.1 - 0.13 12.4 2.1 1.2 9.2 0.0 2.5 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Sporozoite_P67 PF05642.6 CDI73678.1 - 0.22 9.3 2.3 2.1 6.0 0.6 2.1 2 0 0 2 2 2 0 Sporozoite P67 surface antigen Band_3_cyto PF07565.8 CDI73678.1 - 0.29 10.6 15.8 0.3 10.5 6.5 2.1 2 0 0 2 2 2 0 Band 3 cytoplasmic domain DUF2407_C PF13373.1 CDI73678.1 - 0.37 10.6 7.4 0.49 10.3 2.8 2.1 2 0 0 2 2 2 0 DUF2407 C-terminal domain CemA PF03040.9 CDI73678.1 - 1.2 8.7 8.3 1.6 8.2 2.2 2.2 2 0 0 2 2 2 0 CemA family Rtf2 PF04641.7 CDI73678.1 - 1.3 8.1 11.1 0.77 8.9 4.3 2.2 2 0 0 2 2 2 0 Rtf2 RING-finger Herpes_UL87 PF03043.9 CDI73678.1 - 2 6.7 13.0 3.2 6.0 9.0 1.3 1 0 0 1 1 1 0 Herpesvirus UL87 family Na_trans_assoc PF06512.8 CDI73678.1 - 9.7 6.0 8.1 3.4 7.5 3.0 1.9 2 0 0 2 2 2 0 Sodium ion transport-associated Y_phosphatase3 PF13350.1 CDI73679.1 - 0.0016 18.7 2.0 0.0016 18.7 1.4 1.9 2 0 0 2 2 2 1 Tyrosine phosphatase family DUF4228 PF14009.1 CDI73679.1 - 0.12 12.4 12.0 0.16 12.1 8.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4228) Herpes_UL87 PF03043.9 CDI73679.1 - 0.23 9.7 7.5 0.24 9.7 5.2 1.0 1 0 0 1 1 1 0 Herpesvirus UL87 family Mito_fiss_reg PF05308.6 CDI73679.1 - 0.26 10.6 17.6 0.3 10.4 12.2 1.1 1 0 0 1 1 1 0 Mitochondrial fission regulator DUF1510 PF07423.6 CDI73679.1 - 0.35 10.2 16.2 0.49 9.7 3.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) DUF3801 PF12687.2 CDI73679.1 - 0.4 10.2 19.0 0.48 9.9 13.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3801) PRP1_N PF06424.7 CDI73679.1 - 0.51 10.6 13.3 1.3 9.3 0.0 2.1 2 0 0 2 2 2 0 PRP1 splicing factor, N-terminal PAT1 PF09770.4 CDI73679.1 - 0.58 8.3 52.0 0.7 8.0 36.0 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF1644 PF07800.7 CDI73679.1 - 0.62 9.9 12.6 0.16 11.8 0.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1644) RNA_pol_Rpb1_5 PF04998.12 CDI73679.1 - 1.6 7.9 6.0 2.2 7.4 4.2 1.2 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 DUF3402 PF11882.3 CDI73679.1 - 1.6 7.6 14.7 2 7.4 10.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3402) DUF912 PF06024.7 CDI73679.1 - 2 8.4 13.4 6.6 6.8 3.8 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Peptidase_S49_N PF08496.5 CDI73679.1 - 2.3 7.9 17.7 4.4 7.0 6.2 2.1 2 0 0 2 2 2 0 Peptidase family S49 N-terminal DUF1840 PF08895.6 CDI73679.1 - 2.4 8.2 18.4 3.2 7.8 6.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1840) DUF4557 PF15101.1 CDI73679.1 - 2.7 7.7 33.6 2 8.1 12.9 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4557) CPSF100_C PF13299.1 CDI73679.1 - 3 7.9 13.9 3.4 7.8 4.1 2.1 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal FYDLN_acid PF09538.5 CDI73679.1 - 3.6 8.2 10.0 3.8 8.1 1.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) AIF_C PF14721.1 CDI73679.1 - 3.7 7.7 14.3 7.6 6.7 4.1 2.1 2 0 0 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Pex14_N PF04695.8 CDI73679.1 - 4.5 7.3 26.5 6.1 6.9 3.3 2.2 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Neur_chan_memb PF02932.11 CDI73679.1 - 4.8 7.0 10.7 6.4 6.5 7.4 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF775 PF05603.7 CDI73679.1 - 5.8 6.3 23.7 0.75 9.2 7.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF775) RNase_H2_suC PF08615.6 CDI73679.1 - 9.1 6.1 14.6 5.7 6.7 1.2 2.1 2 0 0 2 2 2 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) eIF_4EBP PF05456.6 CDI73679.1 - 9.8 5.9 17.8 2.5 7.8 0.9 2.2 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) HC2 PF07382.6 CDI73680.1 - 1.9e-14 53.9 177.0 9.1e-10 38.7 59.3 3.4 1 1 3 4 4 4 3 Histone H1-like nucleoprotein HC2 TPR_11 PF13414.1 CDI73681.1 - 5.7e-10 38.7 10.1 1.9e-06 27.4 0.0 4.8 3 1 1 4 4 4 2 TPR repeat TPR_2 PF07719.12 CDI73681.1 - 6.8e-10 38.1 6.7 7e-05 22.4 0.0 6.4 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_17 PF13431.1 CDI73681.1 - 8.9e-10 37.9 0.9 0.014 15.5 0.0 5.1 4 1 1 5 5 4 2 Tetratricopeptide repeat TPR_1 PF00515.23 CDI73681.1 - 1.8e-09 36.7 4.7 0.00028 20.3 0.0 6.2 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_14 PF13428.1 CDI73681.1 - 7.8e-09 35.4 18.2 0.0054 17.2 0.1 6.4 5 2 3 8 8 6 4 Tetratricopeptide repeat TPR_19 PF14559.1 CDI73681.1 - 9.5e-09 35.4 22.8 8.8e-06 25.9 0.1 5.9 4 2 1 5 5 4 2 Tetratricopeptide repeat TPR_12 PF13424.1 CDI73681.1 - 1.8e-07 30.9 3.8 0.005 16.7 0.0 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.1 CDI73681.1 - 7.9e-06 25.3 7.1 0.0025 17.4 0.2 5.4 4 2 1 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.1 CDI73681.1 - 8.1e-06 25.2 6.7 0.95 9.4 0.0 5.6 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_16 PF13432.1 CDI73681.1 - 0.0014 19.2 14.0 0.062 13.9 0.0 4.3 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_6 PF13174.1 CDI73681.1 - 0.012 16.0 4.1 0.61 10.6 0.0 4.5 4 1 0 4 4 4 0 Tetratricopeptide repeat PPR PF01535.15 CDI73681.1 - 0.079 12.9 2.4 19 5.5 0.1 3.7 3 0 0 3 3 3 0 PPR repeat Dehydrin PF00257.14 CDI73681.1 - 0.82 9.9 7.0 0.089 13.1 1.5 1.9 3 0 0 3 3 2 0 Dehydrin DUF1826 PF08856.6 CDI73681.1 - 8.2 6.1 10.1 2.5 7.8 0.8 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1826) Cellulose_synt PF03552.9 CDI73682.1 - 0.25 9.5 1.9 0.42 8.8 1.3 1.3 1 0 0 1 1 1 0 Cellulose synthase Zip PF02535.17 CDI73683.1 - 0.08 11.9 8.1 0.1 11.6 5.6 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter s48_45 PF07422.8 CDI73683.1 - 1.6 8.8 6.7 2.4 8.2 4.6 1.3 1 1 0 1 1 1 0 Sexual stage antigen s48/45 domain PAT1 PF09770.4 CDI73683.1 - 2.2 6.3 31.7 2.9 6.0 22.0 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Herpes_U34 PF04541.8 CDI73683.1 - 10 4.9 10.5 0.62 8.9 1.0 2.1 2 0 0 2 2 2 0 Herpesvirus virion protein U34 zf-IS66 PF13005.2 CDI73684.1 - 6.6 6.7 8.2 4.3 7.3 0.1 2.8 3 0 0 3 3 3 0 zinc-finger binding domain of transposase IS66 Galactosyl_T PF01762.16 CDI73685.1 - 2.3e-47 161.1 0.0 3e-47 160.7 0.0 1.1 1 0 0 1 1 1 1 Galactosyltransferase Fringe PF02434.11 CDI73685.1 - 0.028 13.6 0.0 0.044 12.9 0.0 1.3 1 0 0 1 1 1 0 Fringe-like Galactosyl_T PF01762.16 CDI73686.1 - 1.6e-43 148.5 0.0 2e-43 148.2 0.0 1.1 1 0 0 1 1 1 1 Galactosyltransferase Fringe PF02434.11 CDI73686.1 - 0.0015 17.7 0.0 0.002 17.4 0.0 1.1 1 0 0 1 1 1 1 Fringe-like zf-CCHC_3 PF13917.1 CDI73687.1 - 0.0062 16.2 0.2 0.019 14.6 0.1 1.8 1 0 0 1 1 1 1 Zinc knuckle zf-ribbon_3 PF13248.1 CDI73687.1 - 4.3 6.6 10.8 1.5 8.1 1.3 3.0 2 1 1 3 3 3 0 zinc-ribbon domain DUF1196 PF06709.6 CDI73688.1 - 0.84 9.6 2.1 10 6.1 0.7 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1196) DUF1586 PF07625.6 CDI73688.1 - 0.91 9.3 6.4 0.88 9.3 2.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1586) DEAD PF00270.24 CDI73690.1 - 1.1e-42 145.3 0.0 5.1e-41 139.9 0.0 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CDI73690.1 - 2.2e-26 91.5 0.0 6.4e-26 90.0 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 CDI73690.1 - 5.9e-05 22.9 0.0 0.0021 17.9 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SecA_DEAD PF07517.9 CDI73690.1 - 0.00035 19.9 0.1 0.00066 19.0 0.1 1.4 1 0 0 1 1 1 1 SecA DEAD-like domain Helicase_C_2 PF13307.1 CDI73690.1 - 0.0006 19.7 0.1 1.5 8.7 0.0 2.8 3 0 0 3 3 3 2 Helicase C-terminal domain AAA PF00004.24 CDI73691.1 - 1.8e-29 102.6 0.0 3.3e-29 101.7 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 CDI73691.1 - 8.4e-06 25.9 0.0 0.00063 19.8 0.0 2.5 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 CDI73691.1 - 0.0013 17.7 0.0 0.0021 17.1 0.0 1.2 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 CDI73691.1 - 0.0015 18.2 0.2 0.0037 16.9 0.1 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_33 PF13671.1 CDI73691.1 - 0.0015 18.4 0.0 0.0034 17.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 CDI73691.1 - 0.0018 17.6 0.4 0.11 11.9 0.2 2.4 1 1 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 CDI73691.1 - 0.0026 17.2 0.1 0.0046 16.4 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.16 CDI73691.1 - 0.0027 16.9 0.2 0.0051 15.9 0.1 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 CDI73691.1 - 0.003 17.2 0.1 0.0094 15.6 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 CDI73691.1 - 0.0049 16.8 0.4 0.13 12.2 0.0 2.3 1 1 0 2 2 2 1 AAA ATPase domain AAA_28 PF13521.1 CDI73691.1 - 0.009 15.9 0.0 0.021 14.8 0.0 1.5 1 1 0 1 1 1 1 AAA domain NACHT PF05729.7 CDI73691.1 - 0.013 15.1 0.0 0.88 9.2 0.0 2.5 1 1 1 2 2 2 0 NACHT domain AAA_17 PF13207.1 CDI73691.1 - 0.019 15.7 0.0 0.036 14.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_2 PF07724.9 CDI73691.1 - 0.051 13.4 0.0 0.25 11.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain (Cdc48 subfamily) TIP49 PF06068.8 CDI73691.1 - 0.081 11.6 0.0 0.48 9.0 0.0 1.9 1 1 1 2 2 2 0 TIP49 C-terminus RNA_helicase PF00910.17 CDI73691.1 - 0.11 12.7 0.0 0.73 10.0 0.0 2.3 3 0 0 3 3 2 0 RNA helicase Sigma54_activ_2 PF14532.1 CDI73691.1 - 0.12 12.3 0.0 0.26 11.3 0.0 1.6 1 1 0 1 1 1 0 Sigma-54 interaction domain Parvo_NS1 PF01057.12 CDI73691.1 - 0.13 11.0 0.0 0.19 10.5 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AFG1_ATPase PF03969.11 CDI73691.1 - 0.16 10.7 0.1 0.8 8.4 0.0 1.8 1 1 1 2 2 2 0 AFG1-like ATPase Zeta_toxin PF06414.7 CDI73691.1 - 0.21 10.6 0.1 0.38 9.8 0.1 1.3 1 0 0 1 1 1 0 Zeta toxin PhoH PF02562.11 CDI73691.1 - 0.22 10.7 0.1 0.38 9.9 0.1 1.2 1 0 0 1 1 1 0 PhoH-like protein AAA_24 PF13479.1 CDI73691.1 - 0.23 11.0 0.2 0.4 10.2 0.1 1.3 1 0 0 1 1 1 0 AAA domain BTB PF00651.26 CDI73692.1 - 3.9e-15 55.8 0.0 2.8e-14 53.0 0.0 2.2 2 0 0 2 2 2 1 BTB/POZ domain LAT PF15234.1 CDI73693.1 - 3.9 6.8 7.1 2 7.8 3.6 1.4 2 0 0 2 2 2 0 Linker for activation of T-cells PaaSYMP PF14738.1 CDI73694.1 - 2.6e-24 85.6 2.1 2.6e-24 85.6 1.5 3.0 2 1 1 3 3 3 1 Solute carrier (proton/amino acid symporter), TRAMD3 or PAT1 DUF572 PF04502.8 CDI73694.1 - 4.9 6.2 10.0 7.6 5.6 6.4 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF572) DUF755 PF05501.6 CDI73696.1 - 0.024 14.6 9.1 0.05 13.6 6.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF755) SR-25 PF10500.4 CDI73696.1 - 0.87 9.0 17.6 1.3 8.4 12.2 1.4 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein Med15 PF09606.5 CDI73697.1 - 0.00053 18.3 53.6 0.00053 18.3 37.2 5.1 4 1 0 5 5 5 1 ARC105 or Med15 subunit of Mediator complex non-fungal Abhydrolase_9_N PF15420.1 CDI73698.1 - 4.2 7.0 31.4 0.063 13.0 8.8 3.3 2 1 2 4 4 4 0 Alpha/beta-hydrolase family N-terminus Glyco_trans_1_4 PF13692.1 CDI73699.1 - 1.8e-10 41.0 0.0 4.4e-10 39.8 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.15 CDI73699.1 - 0.0062 15.9 0.0 0.15 11.4 0.0 3.2 2 2 1 3 3 3 1 Glycosyl transferases group 1 SPX PF03105.14 CDI73700.1 - 0.0013 18.5 9.5 0.0015 18.3 6.6 1.2 1 0 0 1 1 1 1 SPX domain Otopetrin PF03189.8 CDI73700.1 - 0.064 12.2 0.5 0.093 11.7 0.3 1.4 1 0 0 1 1 1 0 Otopetrin SAGA-Tad1 PF12767.2 CDI73700.1 - 0.08 12.5 24.1 0.13 11.9 16.7 1.3 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit Hid1 PF12722.2 CDI73700.1 - 0.62 7.6 20.4 0.81 7.2 14.1 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Herpes_DNAp_acc PF04929.7 CDI73700.1 - 3.9 6.3 23.9 9.7 5.0 16.6 1.6 1 0 0 1 1 1 0 Herpes DNA replication accessory factor DUF45 PF01863.12 CDI73700.1 - 6.8 6.4 18.1 12 5.6 12.6 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF45 DUF2217 PF10265.4 CDI73701.1 - 0.0029 16.4 0.5 0.0037 16.0 0.4 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2217) Peptidase_C48 PF02902.14 CDI73701.1 - 0.013 15.1 0.0 0.019 14.5 0.0 1.3 1 0 0 1 1 1 0 Ulp1 protease family, C-terminal catalytic domain SR-25 PF10500.4 CDI73701.1 - 0.019 14.4 12.8 0.03 13.7 8.9 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Macoilin PF09726.4 CDI73701.1 - 0.066 11.5 2.9 0.068 11.4 2.0 1.1 1 0 0 1 1 1 0 Transmembrane protein Presenilin PF01080.12 CDI73701.1 - 0.25 10.1 1.3 0.3 9.8 0.9 1.1 1 0 0 1 1 1 0 Presenilin CAF-1_p150 PF11600.3 CDI73701.1 - 1.8 7.8 4.4 2.4 7.4 3.1 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Secretin_N_2 PF07655.8 CDI73701.1 - 5 7.5 16.8 7.6 7.0 11.7 1.2 1 0 0 1 1 1 0 Secretin N-terminal domain RskA PF10099.4 CDI73701.1 - 5.7 6.6 22.0 33 4.1 7.5 2.3 1 1 1 2 2 2 0 Anti-sigma-K factor rskA Med3 PF11593.3 CDI73701.1 - 7.5 5.6 14.1 10 5.2 9.8 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Med15 PF09606.5 CDI73702.1 - 0.11 10.7 87.0 0.12 10.6 60.3 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal PAT1 PF09770.4 CDI73702.1 - 0.21 9.8 76.0 0.25 9.5 52.6 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 HI0933_like PF03486.9 CDI73702.1 - 0.81 8.0 17.8 1 7.7 12.4 1.1 1 0 0 1 1 1 0 HI0933-like protein BTV_NS2 PF04514.7 CDI73702.1 - 3.6 6.3 24.5 4.9 5.9 17.0 1.2 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Neur_chan_memb PF02932.11 CDI73702.1 - 5 6.9 22.8 6.9 6.4 15.8 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Exonuc_VII_L PF02601.10 CDI73702.1 - 7.4 5.6 27.5 9.2 5.3 19.1 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit PLRV_ORF5 PF01690.12 CDI73702.1 - 8.2 5.4 28.7 9.8 5.1 19.9 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Gti1_Pac2 PF09729.4 CDI73703.1 - 3.6 7.4 14.9 5.2 6.9 0.1 3.0 3 0 0 3 3 3 0 Gti1/Pac2 family FimP PF09766.4 CDI73703.1 - 4.3 6.3 30.0 0.77 8.7 6.0 3.1 3 0 0 3 3 3 0 Fms-interacting protein 60KD_IMP PF02096.15 CDI73703.1 - 5.8 6.5 15.3 0.79 9.3 0.8 2.5 2 0 0 2 2 2 0 60Kd inner membrane protein WD40 PF00400.27 CDI73704.1 - 5.1e-13 48.3 1.2 4.9e-06 26.2 0.0 3.4 3 0 0 3 3 3 2 WD domain, G-beta repeat SR-25 PF10500.4 CDI73704.1 - 3.6e-07 29.9 8.5 3.6e-07 29.9 5.9 2.5 2 1 0 2 2 1 1 Nuclear RNA-splicing-associated protein Nup160 PF11715.3 CDI73704.1 - 8.6e-07 27.4 0.4 8.6e-07 27.4 0.3 1.8 2 0 0 2 2 2 1 Nucleoporin Nup120/160 BRF1 PF07741.8 CDI73704.1 - 0.015 15.5 3.2 0.015 15.5 2.2 2.6 2 0 0 2 2 2 0 Brf1-like TBP-binding domain Rxt3 PF08642.5 CDI73704.1 - 0.03 14.5 2.4 0.03 14.5 1.7 2.3 2 1 0 2 2 2 0 Histone deacetylation protein Rxt3 DUF2000 PF09391.5 CDI73704.1 - 0.11 12.1 1.2 0.21 11.2 0.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2000) AIF_C PF14721.1 CDI73704.1 - 0.18 12.0 11.2 1.3 9.2 0.9 2.5 2 0 0 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Peptidase_S49_N PF08496.5 CDI73704.1 - 0.2 11.4 8.4 1.2 8.8 1.6 2.3 2 0 0 2 2 2 0 Peptidase family S49 N-terminal DUF1777 PF08648.7 CDI73704.1 - 0.32 10.7 11.6 1.2 8.8 3.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1777) Gti1_Pac2 PF09729.4 CDI73704.1 - 0.35 10.7 9.8 2.5 7.9 1.4 2.2 2 0 0 2 2 2 0 Gti1/Pac2 family DUF3807 PF12720.2 CDI73704.1 - 0.37 10.9 18.7 1.1 9.4 3.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3807) NST1 PF13945.1 CDI73704.1 - 0.38 10.7 22.9 0.079 13.0 4.9 2.3 2 0 0 2 2 2 0 Salt tolerance down-regulator DUF1117 PF06547.7 CDI73704.1 - 0.55 10.3 5.6 4.3 7.4 4.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1117) UPF0561 PF10573.4 CDI73704.1 - 0.81 9.5 14.5 2.2 8.1 2.0 2.3 2 0 0 2 2 2 0 Uncharacterised protein family UPF0561 DUF1764 PF08576.5 CDI73704.1 - 2.4 9.0 20.4 4.9 7.9 4.7 2.5 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF1764) Asp-B-Hydro_N PF05279.6 CDI73704.1 - 2.6 7.8 17.8 0.33 10.7 4.7 2.1 2 0 0 2 2 2 0 Aspartyl beta-hydroxylase N-terminal region Baculo_PP31 PF05311.6 CDI73704.1 - 3.2 6.9 15.8 4.1 6.6 2.5 2.2 2 0 0 2 2 2 0 Baculovirus 33KDa late protein (PP31) Ipi1_N PF12333.3 CDI73704.1 - 3.8 7.5 14.1 2.8 7.9 1.6 2.9 3 0 0 3 3 3 0 Rix1 complex component involved in 60S ribosome maturation Sox_N PF12444.3 CDI73704.1 - 4.8 8.3 22.2 16 6.7 8.3 2.7 2 0 0 2 2 2 0 Sox developmental protein N terminal FimP PF09766.4 CDI73704.1 - 4.9 6.1 23.7 0.023 13.7 5.9 2.1 2 0 0 2 2 2 0 Fms-interacting protein DUF3633 PF12315.3 CDI73704.1 - 6.8 5.9 11.3 0.7 9.1 3.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3633) Dehydrin PF00257.14 CDI73704.1 - 7.1 6.9 26.1 4.2 7.6 6.0 2.3 2 0 0 2 2 2 0 Dehydrin DUF913 PF06025.7 CDI73704.1 - 7.1 5.2 11.7 5.5 5.6 2.5 2.1 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) Spt20 PF12090.3 CDI73704.1 - 7.2 5.9 16.7 0.067 12.5 2.6 2.4 3 0 0 3 3 3 0 Spt20 family DUF3408 PF11888.3 CDI73704.1 - 7.6 6.4 14.7 2.5 8.0 1.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3408) Dsh_C PF12316.3 CDI73704.1 - 8.4 6.4 22.4 6.4 6.8 8.6 2.2 2 0 0 2 2 2 0 Segment polarity protein dishevelled (Dsh) C terminal DUF4557 PF15101.1 CDI73704.1 - 8.8 6.1 20.8 1 9.1 5.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4557) DUF4602 PF15375.1 CDI73704.1 - 8.8 6.3 26.7 3.1 7.8 9.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4602) TraG-D_C PF12696.2 CDI73704.1 - 9.6 6.0 18.2 5.1 6.9 7.9 2.3 2 0 0 2 2 2 0 TraM recognition site of TraD and TraG AF-4 PF05110.8 CDI73705.1 - 0.0011 17.0 32.2 0.0011 17.0 22.3 4.6 2 1 0 3 3 3 1 AF-4 proto-oncoprotein Zip PF02535.17 CDI73706.1 - 0.0034 16.4 9.5 0.0034 16.4 6.6 1.5 2 0 0 2 2 2 1 ZIP Zinc transporter NicO PF03824.11 CDI73706.1 - 0.12 11.6 5.0 0.18 11.0 3.5 1.2 1 0 0 1 1 1 0 High-affinity nickel-transport protein PAT1 PF09770.4 CDI73706.1 - 2.4 6.2 38.4 3.7 5.6 26.6 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Peptidase_S49_N PF08496.5 CDI73706.1 - 3 7.6 14.7 2.5 7.8 5.9 2.2 2 0 0 2 2 2 0 Peptidase family S49 N-terminal RIC3 PF15361.1 CDI73706.1 - 6.5 6.9 18.4 0.14 12.4 6.0 2.6 3 0 0 3 3 3 0 Resistance to inhibitors of cholinesterase homologue 3 Med3 PF11593.3 CDI73707.1 - 3.2 6.8 6.4 3.3 6.8 4.5 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal ASFV_J13L PF05568.6 CDI73707.1 - 8.7 5.8 8.3 7.4 6.0 4.7 1.5 1 1 0 1 1 1 0 African swine fever virus J13L protein DUF3850 PF12961.2 CDI73708.1 - 0.032 14.1 2.8 2.5 8.1 0.1 2.3 1 1 1 2 2 2 0 Domain of Unknown Function with PDB structure (DUF3850) ALIX_LYPXL_bnd PF13949.1 CDI73710.1 - 0.13 11.2 1.5 0.18 10.7 1.0 1.1 1 0 0 1 1 1 0 ALIX V-shaped domain binding to HIV CD20 PF04103.10 CDI73711.1 - 0.00039 20.3 0.2 0.00039 20.3 0.1 1.6 2 0 0 2 2 2 1 CD20-like family YfhO PF09586.5 CDI73711.1 - 0.00056 18.0 1.3 0.00056 18.0 0.9 1.3 2 0 0 2 2 1 1 Bacterial membrane protein YfhO FimP PF09766.4 CDI73711.1 - 0.0011 18.1 11.6 0.0011 18.1 8.0 2.2 2 0 0 2 2 2 1 Fms-interacting protein DUF3357 PF11837.3 CDI73711.1 - 0.0023 17.7 0.5 0.0023 17.7 0.4 2.6 2 2 1 3 3 2 1 Domain of unknown function (DUF3357) Herpes_DNAp_acc PF04929.7 CDI73711.1 - 0.0063 15.5 17.8 0.011 14.7 12.3 1.3 1 0 0 1 1 1 1 Herpes DNA replication accessory factor Shisa PF13908.1 CDI73711.1 - 0.014 15.5 5.4 0.014 15.5 3.7 2.0 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator Trp_oprn_chp PF09534.5 CDI73711.1 - 0.018 14.6 3.1 0.018 14.6 2.1 2.4 2 1 1 3 3 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Tetraspannin PF00335.15 CDI73711.1 - 0.12 11.6 3.6 0.53 9.5 3.1 1.4 1 1 0 1 1 1 0 Tetraspanin family DUF3373 PF11853.3 CDI73711.1 - 0.41 9.1 9.3 0.44 9.0 6.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) DUF3573 PF12097.3 CDI73711.1 - 0.78 8.2 4.5 0.77 8.3 3.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) Claudin_2 PF13903.1 CDI73711.1 - 1.3 8.6 6.1 2.1 8.0 4.3 1.3 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction Pilt PF15453.1 CDI73711.1 - 1.8 8.1 24.8 2.2 7.8 17.2 1.1 1 0 0 1 1 1 0 Protein incorporated later into Tight Junctions Peptidase_S49_N PF08496.5 CDI73711.1 - 2.8 7.7 31.0 6.5e+03 -3.3 21.5 2.4 1 1 0 1 1 1 0 Peptidase family S49 N-terminal AIF_C PF14721.1 CDI73711.1 - 3.1 8.0 19.5 0.12 12.5 3.2 2.2 2 0 0 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term 7tm_7 PF08395.7 CDI73711.1 - 6.1 5.7 13.0 0.016 14.2 2.6 1.4 2 0 0 2 2 1 0 7tm Chemosensory receptor PAT1 PF09770.4 CDI73711.1 - 6.3 4.9 42.5 7.7 4.6 29.4 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Ribosomal_L37 PF08561.5 CDI73713.1 - 2.3 7.8 5.3 3.4 7.3 3.7 1.6 1 1 0 1 1 1 0 Mitochondrial ribosomal protein L37 DUF3192 PF11399.3 CDI73713.1 - 4.9 7.1 11.5 7.7 6.5 8.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3192) Apt1 PF10351.4 CDI73714.1 - 7.7 5.2 22.0 9.6 4.9 15.3 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Anticodon_1 PF08264.8 CDI73715.1 - 3.7e-11 43.0 0.1 6.2e-11 42.2 0.1 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA CDK2AP PF09806.4 CDI73715.1 - 1.1 9.5 7.5 1.5 9.0 5.2 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein MSP1_C PF07462.6 CDI73715.1 - 1.8 6.8 4.6 2.2 6.5 3.2 1.2 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus BAF1_ABF1 PF04684.8 CDI73715.1 - 5.5 5.7 12.9 9.6 4.9 9.0 1.6 1 1 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor BRF1 PF07741.8 CDI73715.1 - 8.4 6.6 9.6 1.1e+02 3.0 6.4 2.4 2 1 0 2 2 2 0 Brf1-like TBP-binding domain PBP1_TM PF14812.1 CDI73716.1 - 5.8 7.3 12.3 3.1 8.1 0.3 3.6 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Activator_LAG-3 PF11498.3 CDI73717.1 - 0.0002 20.2 102.7 0.0051 15.6 23.6 3.7 3 0 0 3 3 3 3 Transcriptional activator LAG-3 DUF4207 PF13904.1 CDI73717.1 - 0.00083 18.8 34.3 0.00083 18.8 23.8 5.7 5 1 0 5 5 5 1 Domain of unknown function (DUF4207) PBP1_TM PF14812.1 CDI73717.1 - 0.011 16.0 13.5 0.011 16.0 9.4 5.2 5 0 0 5 5 5 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF3365 PF11845.3 CDI73719.1 - 0.0032 17.3 3.7 0.0033 17.3 2.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3365) Protocadherin PF08374.6 CDI73719.1 - 0.01 15.5 0.4 0.011 15.3 0.3 1.0 1 0 0 1 1 1 0 Protocadherin Baculo_11_kDa PF06143.6 CDI73719.1 - 0.039 13.2 0.5 0.039 13.2 0.4 2.0 1 1 1 2 2 2 0 Baculovirus 11 kDa family TMEM51 PF15345.1 CDI73719.1 - 0.058 13.0 6.3 0.06 13.0 4.4 1.0 1 0 0 1 1 1 0 Transmembrane protein 51 SHR3_chaperone PF08229.6 CDI73719.1 - 0.11 11.4 8.9 0.12 11.3 6.2 1.0 1 0 0 1 1 1 0 ER membrane protein SH3 Stig1 PF04885.8 CDI73719.1 - 0.16 12.1 0.7 0.19 11.9 0.5 1.0 1 0 0 1 1 1 0 Stigma-specific protein, Stig1 Folate_carrier PF01770.13 CDI73719.1 - 0.17 10.3 1.9 0.17 10.3 1.3 1.0 1 0 0 1 1 1 0 Reduced folate carrier MSC PF09402.5 CDI73719.1 - 0.18 10.4 3.9 0.19 10.4 2.7 1.0 1 0 0 1 1 1 0 Man1-Src1p-C-terminal domain DUF3260 PF11658.3 CDI73719.1 - 0.21 9.7 4.1 0.23 9.5 2.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3260) AUX_IAA PF02309.11 CDI73719.1 - 0.3 10.7 2.8 0.31 10.7 1.9 1.0 1 0 0 1 1 1 0 AUX/IAA family Serinc PF03348.10 CDI73719.1 - 0.36 9.4 2.7 0.36 9.5 1.9 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) Neur_chan_memb PF02932.11 CDI73719.1 - 0.37 10.6 3.0 0.39 10.5 2.1 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Mem_trans PF03547.13 CDI73719.1 - 0.39 8.9 1.5 0.45 8.7 1.1 1.0 1 0 0 1 1 1 0 Membrane transport protein Conotoxin PF02950.12 CDI73719.1 - 0.4 11.5 10.4 2 9.3 7.2 1.8 1 1 0 1 1 1 0 Conotoxin ABC2_membrane_2 PF12679.2 CDI73719.1 - 0.45 9.3 1.7 0.47 9.2 1.1 1.0 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF2149 PF09919.4 CDI73719.1 - 0.68 10.0 3.3 0.83 9.7 2.3 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2149) DUF1764 PF08576.5 CDI73719.1 - 0.71 10.6 5.8 0.8 10.5 4.0 1.1 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) Shisa PF13908.1 CDI73719.1 - 0.83 9.8 7.5 0.84 9.7 5.2 1.0 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator GRP PF07172.6 CDI73719.1 - 0.94 9.9 6.9 3.1 8.3 4.8 1.7 1 1 0 1 1 1 0 Glycine rich protein family DUF2232 PF09991.4 CDI73719.1 - 1.2 8.0 5.7 1.5 7.7 3.9 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) YfhO PF09586.5 CDI73719.1 - 1.3 6.9 5.4 1.4 6.8 3.7 1.0 1 0 0 1 1 1 0 Bacterial membrane protein YfhO OATP PF03137.15 CDI73719.1 - 1.3 7.0 3.9 1.4 6.9 2.7 1.0 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Endonuc_Holl PF10107.4 CDI73719.1 - 1.5 8.4 5.3 1.9 8.1 3.6 1.1 1 0 0 1 1 1 0 Endonuclease related to archaeal Holliday junction resolvase DUF3357 PF11837.3 CDI73719.1 - 3.5 7.5 5.3 45 3.9 3.7 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF3357) EphA2_TM PF14575.1 CDI73719.1 - 4.7 7.6 9.1 92 3.5 6.3 2.0 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Band_3_cyto PF07565.8 CDI73719.1 - 5.1 6.5 8.1 5.2 6.5 5.6 1.0 1 0 0 1 1 1 0 Band 3 cytoplasmic domain DUF4589 PF15252.1 CDI73720.1 - 0.0015 18.4 2.9 0.0015 18.4 2.0 2.3 2 1 0 2 2 2 1 Domain of unknown function (DUF4589) Sporozoite_P67 PF05642.6 CDI73720.1 - 0.77 7.5 6.3 1.2 6.8 4.4 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF2029 PF09594.5 CDI73720.1 - 8.5 5.7 28.3 0.15 11.5 10.3 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2029) Tau95 PF09734.4 CDI73721.1 - 0.0037 16.6 0.7 0.008 15.5 0.1 1.8 1 1 1 2 2 2 2 RNA polymerase III transcription factor (TF)IIIC subunit Nop53 PF07767.6 CDI73722.1 - 0.00028 20.0 18.0 0.00029 19.9 12.5 1.2 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) PcfK PF14058.1 CDI73722.1 - 0.019 15.1 12.7 0.022 14.8 8.8 1.2 1 0 0 1 1 1 0 PcfK-like protein Med15 PF09606.5 CDI73722.1 - 0.022 12.9 30.5 0.02 13.0 21.1 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal SprA-related PF12118.3 CDI73722.1 - 0.022 14.0 36.9 0.028 13.7 25.6 1.1 1 0 0 1 1 1 0 SprA-related family Daxx PF03344.10 CDI73722.1 - 0.047 12.1 19.6 0.06 11.8 13.6 1.2 1 0 0 1 1 1 0 Daxx Family Zip PF02535.17 CDI73722.1 - 0.068 12.1 7.4 0.075 12.0 5.1 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Spt5_N PF11942.3 CDI73722.1 - 0.52 10.9 20.7 0.86 10.2 14.4 1.3 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal RR_TM4-6 PF06459.7 CDI73722.1 - 0.59 9.9 18.7 0.68 9.7 13.0 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Suf PF05843.9 CDI73722.1 - 0.61 9.7 19.9 0.73 9.5 13.8 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Radical_SAM_N PF08497.5 CDI73722.1 - 0.66 8.8 6.9 0.65 8.8 4.8 1.1 1 0 0 1 1 1 0 Radical SAM N-terminal Peptidase_U57 PF05582.7 CDI73722.1 - 0.71 8.7 9.7 0.83 8.5 6.7 1.2 1 0 0 1 1 1 0 YabG peptidase U57 Adaptin_binding PF10199.4 CDI73722.1 - 0.78 10.0 22.1 1.1 9.5 15.3 1.2 1 0 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 Serinc PF03348.10 CDI73722.1 - 1.3 7.6 13.3 1.5 7.4 9.2 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) Ycf1 PF05758.7 CDI73722.1 - 1.6 6.3 16.6 1.6 6.3 11.5 1.2 1 0 0 1 1 1 0 Ycf1 OmpH PF03938.9 CDI73722.1 - 1.6 8.6 28.4 1.9 8.3 19.7 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) AAA_23 PF13476.1 CDI73722.1 - 1.7 8.9 26.0 2 8.7 18.0 1.1 1 0 0 1 1 1 0 AAA domain DUF4011 PF13195.1 CDI73722.1 - 1.7 8.6 12.3 2.1 8.3 8.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4011) Silic_transp PF03842.8 CDI73722.1 - 1.8 6.5 7.5 2.1 6.3 5.2 1.1 1 0 0 1 1 1 0 Silicon transporter TFIIA PF03153.8 CDI73722.1 - 1.8 8.3 29.0 2.2 8.0 20.1 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4175 PF13779.1 CDI73722.1 - 1.9 6.1 38.2 2.2 5.8 26.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Raftlin PF15250.1 CDI73722.1 - 2.1 6.7 17.4 2.7 6.4 12.1 1.1 1 0 0 1 1 1 0 Raftlin APG6 PF04111.7 CDI73722.1 - 3.2 6.7 20.0 3.2 6.7 13.9 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 Paramyxo_ncap PF00973.14 CDI73722.1 - 3.8 6.0 11.4 4.1 5.9 7.9 1.2 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein DUF1501 PF07394.7 CDI73722.1 - 4 6.1 13.5 4.5 5.9 9.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) SAGA-Tad1 PF12767.2 CDI73722.1 - 4 7.0 21.8 5.3 6.6 15.1 1.1 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit DUF913 PF06025.7 CDI73722.1 - 6 5.5 11.3 7.7 5.1 7.9 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Na_trans_assoc PF06512.8 CDI73722.1 - 7.2 6.5 17.8 9.9 6.0 12.3 1.2 1 0 0 1 1 1 0 Sodium ion transport-associated GAGA_bind PF06217.7 CDI73722.1 - 9.5 6.0 17.8 11 5.8 12.4 1.0 1 0 0 1 1 1 0 GAGA binding protein-like family Strabismus PF06638.6 CDI73723.1 - 7.1 4.8 13.2 7.1 4.8 9.2 1.0 1 0 0 1 1 1 0 Strabismus protein Mem_trans PF03547.13 CDI73723.1 - 8.6 4.5 21.4 8.8 4.5 14.8 1.0 1 0 0 1 1 1 0 Membrane transport protein Rcd1 PF04078.8 CDI73724.1 - 6.4e-15 54.7 0.1 6.4e-15 54.7 0.1 2.4 2 0 0 2 2 2 1 Cell differentiation family, Rcd1-like Shadoo PF14999.1 CDI73724.1 - 0.0048 16.7 6.3 0.0071 16.2 4.3 1.2 1 0 0 1 1 1 1 Shadow of prion protein, neuroprotective Ribosomal_60s PF00428.14 CDI73724.1 - 0.47 10.8 10.9 1.1 9.7 7.6 1.6 1 0 0 1 1 1 0 60s Acidic ribosomal protein PAT1 PF09770.4 CDI73725.1 - 9 4.3 58.6 9.9 4.2 40.6 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SR-25 PF10500.4 CDI73726.1 - 0.00034 20.1 17.7 0.00034 20.1 12.3 9.1 3 2 3 8 8 8 2 Nuclear RNA-splicing-associated protein SR-25 PF10500.4 CDI73727.1 - 0.00019 20.9 2.8 0.00019 20.9 1.9 5.4 4 1 1 5 5 5 2 Nuclear RNA-splicing-associated protein MFS_Mycoplasma PF07672.8 CDI73727.1 - 0.48 9.5 1.1 1.2 8.2 0.7 1.6 1 0 0 1 1 1 0 Mycoplasma MFS transporter Spt20 PF12090.3 CDI73728.1 - 0.03 13.6 0.1 0.03 13.6 0.1 8.8 4 2 1 5 5 5 0 Spt20 family DUF3801 PF12687.2 CDI73728.1 - 0.031 13.8 0.3 0.031 13.8 0.2 7.7 6 3 0 6 6 6 0 Protein of unknown function (DUF3801) BAF1_ABF1 PF04684.8 CDI73729.1 - 9.6 4.9 11.7 13 4.5 8.1 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor DUF1162 PF06650.7 CDI73730.1 - 4.2e-06 26.1 0.0 2.3e-05 23.7 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1162) Chorein_N PF12624.2 CDI73731.1 - 6.9e-31 106.2 0.0 1.8e-30 104.8 0.0 1.8 1 0 0 1 1 1 1 N-terminal region of Chorein, a TM vesicle-mediated sorter Abhydrolase_3 PF07859.8 CDI73733.1 - 6.4e-10 38.9 0.0 1.2e-09 38.0 0.0 1.5 2 0 0 2 2 2 1 alpha/beta hydrolase fold COesterase PF00135.23 CDI73733.1 - 6e-05 21.9 0.1 9.1e-05 21.3 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.16 CDI73733.1 - 0.0085 15.3 0.0 0.012 14.8 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family DUF2424 PF10340.4 CDI73733.1 - 0.055 12.1 0.0 0.076 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 CDI73733.1 - 0.087 12.5 0.0 0.091 12.5 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family ACP_syn_III_C PF08541.5 CDI73734.1 - 2.3e-34 117.2 0.0 1e-33 115.1 0.0 2.0 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ACP_syn_III PF08545.5 CDI73734.1 - 1.4e-23 82.2 0.3 4.8e-23 80.6 0.2 2.0 1 1 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Chal_sti_synt_C PF02797.10 CDI73734.1 - 4.5e-07 29.9 0.0 8.2e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 Chalcone and stilbene synthases, C-terminal domain Pex14_N PF04695.8 CDI73734.1 - 0.02 14.9 0.2 0.044 13.8 0.2 1.6 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Cupin_4 PF08007.7 CDI73735.1 - 1e-17 64.4 0.0 1e-17 64.4 0.0 2.3 2 0 0 2 2 2 1 Cupin superfamily protein Cupin_8 PF13621.1 CDI73735.1 - 0.00011 21.8 0.0 0.00011 21.8 0.0 2.4 1 1 0 2 2 2 1 Cupin-like domain Cupin_2 PF07883.6 CDI73735.1 - 0.016 14.6 0.0 0.038 13.4 0.0 1.6 1 0 0 1 1 1 0 Cupin domain Ribosomal_60s PF00428.14 CDI73735.1 - 0.026 14.9 7.6 0.026 14.9 5.3 1.9 2 0 0 2 2 2 0 60s Acidic ribosomal protein Cupin_6 PF12852.2 CDI73735.1 - 0.11 12.1 0.0 0.11 12.1 0.0 2.3 2 1 0 2 2 2 0 Cupin Mem_trans PF03547.13 CDI73735.1 - 0.22 9.7 3.1 0.26 9.5 2.2 1.3 1 0 0 1 1 1 0 Membrane transport protein SAGA-Tad1 PF12767.2 CDI73735.1 - 0.83 9.2 31.6 0.18 11.4 19.2 1.7 2 0 0 2 2 2 0 Transcriptional regulator of RNA polII, SAGA, subunit ARD PF03079.9 CDI73735.1 - 3.6 7.5 0.0 3.6 7.5 0.0 3.7 3 1 0 3 3 3 0 ARD/ARD' family WD40 PF00400.27 CDI73736.1 - 2e-53 176.4 31.7 1.5e-12 46.8 0.0 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat PQQ_3 PF13570.1 CDI73736.1 - 0.00011 22.3 0.5 0.012 15.8 0.0 3.6 3 1 0 3 3 3 1 PQQ-like domain Nup160 PF11715.3 CDI73736.1 - 0.019 13.1 13.9 0.87 7.6 1.0 4.4 2 1 3 5 5 5 0 Nucleoporin Nup120/160 Citrate_synt PF00285.16 CDI73737.1 - 1.2e-81 274.2 0.0 7.1e-44 149.9 0.0 2.0 2 0 0 2 2 2 2 Citrate synthase Bac_luciferase PF00296.15 CDI73738.1 - 1.2 8.2 4.3 1.7 7.6 3.0 1.4 1 0 0 1 1 1 0 Luciferase-like monooxygenase PI31_Prot_C PF08577.6 CDI73738.1 - 1.3 9.7 5.4 2.4 8.8 3.8 1.5 1 0 0 1 1 1 0 PI31 proteasome regulator Mitofilin PF09731.4 CDI73738.1 - 1.7 7.1 29.0 2.7 6.5 20.1 1.3 1 0 0 1 1 1 0 Mitochondrial inner membrane protein TPP_enzyme_C PF02775.16 CDI73738.1 - 3 7.3 8.3 0.34 10.4 2.4 1.8 1 1 1 2 2 2 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DUF3295 PF11702.3 CDI73738.1 - 4.2 6.2 20.3 4.9 6.0 14.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) TFIIA PF03153.8 CDI73738.1 - 5.5 6.7 33.3 6.8 6.4 23.1 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Hom_end_hint PF05203.11 CDI73738.1 - 6.4 6.4 14.7 8.5 6.0 10.2 1.1 1 0 0 1 1 1 0 Hom_end-associated Hint PIH1 PF08190.7 CDI73738.1 - 8 5.7 24.2 9.5 5.5 16.8 1.1 1 0 0 1 1 1 0 pre-RNA processing PIH1/Nop17 PAT1 PF09770.4 CDI73738.1 - 8.7 4.4 35.4 11 4.1 24.6 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Ycf1 PF05758.7 CDI73738.1 - 9.9 3.7 20.3 11 3.5 14.1 1.0 1 0 0 1 1 1 0 Ycf1 Med15 PF09606.5 CDI73739.1 - 0.0003 19.1 68.5 0.0003 19.1 47.5 7.9 3 2 4 7 7 7 2 ARC105 or Med15 subunit of Mediator complex non-fungal Herpes_UL87 PF03043.9 CDI73739.1 - 0.016 13.6 0.0 0.016 13.6 0.0 6.9 2 2 3 6 6 6 0 Herpesvirus UL87 family Glyoxalase_5 PF14696.1 CDI73740.1 - 3.9 7.4 5.7 1.5 8.7 2.3 1.6 1 1 1 2 2 2 0 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal Toprim_3 PF13362.1 CDI73741.1 - 0.087 13.0 5.5 2.9 8.1 0.2 2.3 2 0 0 2 2 2 0 Toprim domain DUF4562 PF15123.1 CDI73741.1 - 0.25 11.2 5.0 0.4 10.5 3.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4562) Tub PF01167.13 CDI73741.1 - 0.3 10.0 3.9 0.42 9.5 2.7 1.2 1 0 0 1 1 1 0 Tub family Macoilin PF09726.4 CDI73741.1 - 0.4 8.9 12.6 0.49 8.6 8.7 1.0 1 0 0 1 1 1 0 Transmembrane protein RAB3GAP2_N PF14655.1 CDI73741.1 - 0.51 9.2 6.3 0.52 9.2 3.7 1.5 1 1 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus TFIIA PF03153.8 CDI73741.1 - 3.6 7.3 28.1 5.1 6.8 19.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit IncA PF04156.9 CDI73741.1 - 4.8 6.7 20.8 6.2 6.3 14.4 1.4 1 1 0 1 1 1 0 IncA protein PAT1 PF09770.4 CDI73741.1 - 6.4 4.8 30.3 7.4 4.6 21.0 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Herpes_UL21 PF03252.8 CDI73741.1 - 7.7 4.8 8.8 1.9 6.8 3.0 1.8 1 1 1 2 2 2 0 Herpesvirus UL21 SR-25 PF10500.4 CDI73741.1 - 8.2 5.8 10.2 3.1 7.1 5.2 1.7 1 1 1 2 2 2 0 Nuclear RNA-splicing-associated protein DUF4011 PF13195.1 CDI73741.1 - 9.2 6.2 9.7 8.7 6.3 5.5 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF4011) SprA-related PF12118.3 CDI73742.1 - 1.1e-05 24.9 26.0 1.1e-05 24.9 18.0 11.6 6 2 2 8 8 8 1 SprA-related family N6_N4_Mtase PF01555.13 CDI73742.1 - 0.0025 17.3 0.0 11 5.4 0.0 5.0 4 2 0 4 4 4 1 DNA methylase Dehydrin PF00257.14 CDI73742.1 - 0.0031 17.8 0.0 0.0031 17.8 0.0 11.7 8 5 1 10 10 10 2 Dehydrin DUF1510 PF07423.6 CDI73744.1 - 0.0012 18.2 24.1 0.0014 18.0 16.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) SID-1_RNA_chan PF13965.1 CDI73744.1 - 0.25 9.4 20.2 0.29 9.2 14.0 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Raftlin PF15250.1 CDI73744.1 - 0.59 8.5 25.9 0.67 8.4 18.0 1.0 1 0 0 1 1 1 0 Raftlin NPR3 PF03666.8 CDI73744.1 - 0.67 8.4 25.9 0.76 8.2 18.0 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 CDC45 PF02724.9 CDI73744.1 - 0.74 7.7 27.7 0.79 7.6 19.2 1.0 1 0 0 1 1 1 0 CDC45-like protein Ycf1 PF05758.7 CDI73744.1 - 1.2 6.7 26.7 1.3 6.6 18.5 1.0 1 0 0 1 1 1 0 Ycf1 MRI PF15325.1 CDI73744.1 - 1.4 9.9 10.8 1.8 9.5 7.5 1.1 1 0 0 1 1 1 0 Modulator of retrovirus infection Rtf2 PF04641.7 CDI73744.1 - 1.6 7.8 25.8 2.2 7.4 17.9 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger DUF913 PF06025.7 CDI73744.1 - 2 7.0 14.2 3 6.4 9.8 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Neur_chan_memb PF02932.11 CDI73744.1 - 2.1 8.1 23.7 2.5 7.8 16.4 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Pox_Ag35 PF03286.9 CDI73744.1 - 2.2 7.7 19.4 2.6 7.5 13.4 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DUF1183 PF06682.7 CDI73744.1 - 2.7 7.4 17.8 3.3 7.2 12.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) Mem_trans PF03547.13 CDI73744.1 - 3.1 5.9 14.6 3.8 5.6 10.1 1.2 1 0 0 1 1 1 0 Membrane transport protein Herpes_UL87 PF03043.9 CDI73744.1 - 3.3 5.9 18.0 3.8 5.7 12.5 1.0 1 0 0 1 1 1 0 Herpesvirus UL87 family DUF4638 PF15472.1 CDI73744.1 - 3.4 7.1 21.9 4 6.9 15.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) Herpes_DNAp_acc PF04929.7 CDI73744.1 - 3.6 6.4 25.2 4.4 6.1 17.5 1.0 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Otopetrin PF03189.8 CDI73744.1 - 4.4 6.2 18.3 5.4 5.9 12.7 1.1 1 0 0 1 1 1 0 Otopetrin ExbD PF02472.11 CDI73744.1 - 5.3 7.0 12.7 6.8 6.6 8.8 1.3 1 0 0 1 1 1 0 Biopolymer transport protein ExbD/TolR Herpes_env PF01673.13 CDI73744.1 - 5.4 5.4 20.1 6.5 5.1 13.9 1.1 1 0 0 1 1 1 0 Herpesvirus putative major envelope glycoprotein SAPS PF04499.10 CDI73744.1 - 6.3 5.3 27.2 7.1 5.1 18.9 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein CKAP2_C PF15297.1 CDI73744.1 - 7.2 5.3 29.1 9.8 4.8 20.2 1.1 1 0 0 1 1 1 0 Cytoskeleton-associated protein 2 C-terminus FAM60A PF15396.1 CDI73744.1 - 9.3 5.9 29.0 11 5.6 20.1 1.0 1 0 0 1 1 1 0 Protein Family FAM60A Tim54 PF11711.3 CDI73744.1 - 9.8 4.6 20.0 16 3.9 13.9 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Surface_antigen PF11054.3 CDI73745.1 - 4.2e-25 88.5 9.3 1.5e-24 86.8 6.1 1.9 2 0 0 2 2 2 1 Sporozoite TA4 surface antigen Dicty_REP PF05086.7 CDI73745.1 - 4.9 4.7 9.9 6.4 4.3 6.9 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Herpes_DNAp_acc PF04929.7 CDI73746.1 - 0.72 8.7 0.0 0.72 8.7 0.0 19.1 8 2 8 18 18 18 0 Herpes DNA replication accessory factor AAA_23 PF13476.1 CDI73747.1 - 0.0011 19.2 8.9 0.0014 18.9 6.1 1.2 1 0 0 1 1 1 1 AAA domain FimP PF09766.4 CDI73747.1 - 0.011 14.8 5.2 0.011 14.8 3.6 2.2 2 0 0 2 2 2 0 Fms-interacting protein TFIIA PF03153.8 CDI73747.1 - 0.076 12.9 29.0 0.12 12.2 20.1 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CAF-1_p150 PF11600.3 CDI73747.1 - 1.7 7.9 33.1 0.78 9.0 12.2 2.1 1 1 1 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Bud13 PF09736.4 CDI73747.1 - 2.2 8.5 18.2 0.78 9.9 1.9 2.3 2 0 0 2 2 2 0 Pre-mRNA-splicing factor of RES complex PAT1 PF09770.4 CDI73747.1 - 2.8 6.0 32.0 3.6 5.6 22.2 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF2217 PF10265.4 CDI73747.1 - 3.6 6.2 20.2 4.6 5.8 14.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) DUF2422 PF10337.4 CDI73747.1 - 6.8 5.3 14.9 2.9 6.6 3.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2422) Peptidase_S64 PF08192.6 CDI73747.1 - 8.2 4.6 21.8 11 4.1 15.1 1.3 1 0 0 1 1 1 0 Peptidase family S64 Baculo_PP31 PF05311.6 CDI73748.1 - 0.16 11.1 11.3 0.16 11.1 7.8 1.1 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) FimP PF09766.4 CDI73748.1 - 0.22 10.5 23.9 0.24 10.4 16.5 1.1 1 0 0 1 1 1 0 Fms-interacting protein MMR1 PF08505.5 CDI73748.1 - 0.26 11.3 18.1 0.29 11.1 12.5 1.0 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein RR_TM4-6 PF06459.7 CDI73748.1 - 0.31 10.9 11.8 0.35 10.7 8.2 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SprA-related PF12118.3 CDI73748.1 - 0.34 10.1 32.5 0.36 10.1 22.5 1.0 1 0 0 1 1 1 0 SprA-related family CRF1 PF10380.4 CDI73748.1 - 0.54 10.6 7.0 0.58 10.5 4.8 1.2 1 0 0 1 1 1 0 Transcription factor CRF1 Pex14_N PF04695.8 CDI73748.1 - 0.58 10.2 21.1 0.62 10.1 14.6 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Suf PF05843.9 CDI73748.1 - 0.7 9.5 18.1 0.77 9.4 12.6 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) NARP1 PF12569.3 CDI73748.1 - 0.79 8.3 12.4 0.76 8.4 8.6 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Peptidase_S49_N PF08496.5 CDI73748.1 - 0.99 9.1 11.0 1 9.1 7.6 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal CDC45 PF02724.9 CDI73748.1 - 1 7.2 12.4 1.1 7.2 8.6 1.0 1 0 0 1 1 1 0 CDC45-like protein DDHD PF02862.12 CDI73748.1 - 1.1 9.0 12.0 1.1 9.0 8.3 1.1 1 0 0 1 1 1 0 DDHD domain Filo_glycop PF01611.11 CDI73748.1 - 1.1 7.9 9.0 1.2 7.8 6.2 1.0 1 0 0 1 1 1 0 Filovirus glycoprotein AUX_IAA PF02309.11 CDI73748.1 - 1.2 8.8 10.6 1.2 8.8 7.4 1.1 1 0 0 1 1 1 0 AUX/IAA family Peptidase_U57 PF05582.7 CDI73748.1 - 1.3 7.9 9.7 1.5 7.7 6.8 1.1 1 0 0 1 1 1 0 YabG peptidase U57 PAT1 PF09770.4 CDI73748.1 - 1.3 7.1 31.7 1.4 7.0 21.9 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 FLO_LFY PF01698.11 CDI73748.1 - 1.5 7.6 13.8 1.5 7.6 9.6 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein GvpL_GvpF PF06386.6 CDI73748.1 - 1.6 8.2 13.0 1.7 8.1 9.0 1.0 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF PIH1 PF08190.7 CDI73748.1 - 1.7 8.0 15.8 1.7 8.0 11.0 1.0 1 0 0 1 1 1 0 pre-RNA processing PIH1/Nop17 eIF-3_zeta PF05091.7 CDI73748.1 - 2.1 6.8 18.0 2 6.9 12.5 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Band_3_cyto PF07565.8 CDI73748.1 - 2.2 7.7 15.0 2.5 7.5 10.4 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain DUF4407 PF14362.1 CDI73748.1 - 2.3 7.0 17.7 2.4 7.0 12.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF4557 PF15101.1 CDI73748.1 - 2.4 7.9 24.1 2.4 7.9 16.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) AIF_C PF14721.1 CDI73748.1 - 2.7 8.2 10.6 3 8.1 7.3 1.2 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Gag_spuma PF03276.9 CDI73748.1 - 2.7 6.2 29.7 2.7 6.2 20.6 1.0 1 0 0 1 1 1 0 Spumavirus gag protein DHHW PF14286.1 CDI73748.1 - 2.8 7.1 9.2 2.8 7.1 6.4 1.0 1 0 0 1 1 1 0 DHHW protein Paf1 PF03985.8 CDI73748.1 - 3.4 6.3 18.9 3.4 6.2 13.1 1.0 1 0 0 1 1 1 0 Paf1 DUF3381 PF11861.3 CDI73748.1 - 3.8 6.9 14.6 4 6.9 10.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) zf-DHHC PF01529.15 CDI73748.1 - 4.1 6.7 7.4 5.1 6.4 5.1 1.2 1 0 0 1 1 1 0 DHHC palmitoyltransferase Spore_coat_CotO PF14153.1 CDI73748.1 - 5.1 6.4 20.2 5.7 6.3 14.0 1.1 1 0 0 1 1 1 0 Spore coat protein CotO Serinc PF03348.10 CDI73748.1 - 6.1 5.4 12.9 5.9 5.4 8.9 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) DUF4175 PF13779.1 CDI73748.1 - 6.2 4.3 41.3 6.5 4.3 28.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) MSA-2c PF12238.3 CDI73748.1 - 6.3 6.4 9.6 7 6.2 6.7 1.1 1 0 0 1 1 1 0 Merozoite surface antigen 2c CPSF100_C PF13299.1 CDI73748.1 - 7 6.8 12.0 7.9 6.6 8.3 1.1 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Herpes_DNAp_acc PF04929.7 CDI73748.1 - 7 5.5 9.9 7 5.5 6.9 1.0 1 0 0 1 1 1 0 Herpes DNA replication accessory factor IncA PF04156.9 CDI73748.1 - 7.8 6.0 22.2 8 6.0 15.4 1.2 1 0 0 1 1 1 0 IncA protein DUF1682 PF07946.9 CDI73748.1 - 9.5 4.9 13.6 9.3 4.9 9.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Neur_chan_memb PF02932.11 CDI73748.1 - 9.9 5.9 7.6 10 5.9 5.3 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Pet20 PF08692.5 CDI73749.1 - 0.72 9.7 0.0 0.72 9.7 0.0 3.0 3 0 0 3 3 3 0 Mitochondrial protein Pet20 Med15 PF09606.5 CDI73749.1 - 8 4.5 132.2 0.02 13.1 10.6 4.3 4 0 0 4 4 4 0 ARC105 or Med15 subunit of Mediator complex non-fungal Spt20 PF12090.3 CDI73751.1 - 0.014 14.7 7.5 0.06 12.7 0.9 2.3 2 0 0 2 2 2 0 Spt20 family LIM_bind PF01803.11 CDI73751.1 - 0.019 14.0 8.0 0.68 8.9 1.6 2.4 2 0 0 2 2 2 0 LIM-domain binding protein DUF3371 PF11851.3 CDI73751.1 - 0.022 15.4 11.5 0.78 10.4 0.7 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3371) RAB3GAP2_N PF14655.1 CDI73751.1 - 0.28 10.1 8.6 0.68 8.8 0.7 2.3 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus SpoVR PF04293.8 CDI73751.1 - 2.2 6.5 8.3 0.23 9.7 1.2 2.1 2 0 0 2 2 2 0 SpoVR like protein Pex14_N PF04695.8 CDI73751.1 - 5.6 7.0 24.0 1.5 8.8 5.8 3.2 2 1 1 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF2235 PF09994.4 CDI73751.1 - 7.8 5.7 11.3 0.17 11.2 1.9 2.2 2 1 0 2 2 2 0 Uncharacterized alpha/beta hydrolase domain (DUF2235) DUF2339 PF10101.4 CDI73752.1 - 0.078 11.2 3.8 0.1 10.8 2.6 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2339) Med3 PF11593.3 CDI73752.1 - 9 5.4 18.8 6.4 5.8 1.9 2.1 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal FimP PF09766.4 CDI73753.1 - 0.0056 15.7 20.6 0.0056 15.7 14.3 1.0 1 0 0 1 1 1 1 Fms-interacting protein tRNA-synt_1c PF00749.16 CDI73753.1 - 0.075 11.6 5.9 0.09 11.4 4.1 1.0 1 0 0 1 1 1 0 tRNA synthetases class I (E and Q), catalytic domain Rot1 PF10681.4 CDI73753.1 - 0.13 11.5 5.5 0.14 11.5 3.8 1.0 1 0 0 1 1 1 0 Chaperone for protein-folding within the ER, fungal DUF1764 PF08576.5 CDI73753.1 - 0.16 12.7 12.4 0.19 12.5 8.6 1.1 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) DUF3484 PF11983.3 CDI73753.1 - 0.17 12.7 16.9 0.21 12.4 11.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3484) PBP1_TM PF14812.1 CDI73753.1 - 0.2 11.9 2.8 0.22 11.8 1.9 1.1 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal TraH_2 PF06871.6 CDI73753.1 - 0.26 10.6 4.7 0.27 10.6 3.2 1.0 1 0 0 1 1 1 0 TraH_2 Dala_Dala_lig_N PF01820.16 CDI73753.1 - 0.3 11.4 4.7 0.3 11.3 3.2 1.1 1 0 0 1 1 1 0 D-ala D-ala ligase N-terminus DUF912 PF06024.7 CDI73753.1 - 0.3 11.1 6.9 0.35 10.9 4.8 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Pal1 PF08316.6 CDI73753.1 - 0.32 11.4 3.9 0.39 11.1 2.7 1.1 1 0 0 1 1 1 0 Pal1 cell morphology protein DUF913 PF06025.7 CDI73753.1 - 0.32 9.6 5.9 0.35 9.5 4.1 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DUF2126 PF09899.4 CDI73753.1 - 0.42 8.5 10.8 0.41 8.6 7.5 1.0 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) GOLD_2 PF13897.1 CDI73753.1 - 0.53 10.4 3.0 0.56 10.4 2.1 1.1 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking Rxt3 PF08642.5 CDI73753.1 - 0.55 10.4 5.5 0.64 10.2 3.8 1.2 1 0 0 1 1 1 0 Histone deacetylation protein Rxt3 DUF406 PF04175.7 CDI73753.1 - 0.6 10.6 8.8 0.71 10.3 6.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF406) Kei1 PF08552.6 CDI73753.1 - 0.76 9.4 7.1 0.72 9.4 4.9 1.0 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 DUF3449 PF11931.3 CDI73753.1 - 0.79 9.1 11.9 0.88 9.0 8.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3449) AIF_C PF14721.1 CDI73753.1 - 0.81 9.9 9.5 0.86 9.8 6.6 1.1 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term tRNA_synt_1c_R2 PF04557.10 CDI73753.1 - 0.88 10.3 6.4 1.1 9.9 4.4 1.2 1 0 0 1 1 1 0 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 Folate_carrier PF01770.13 CDI73753.1 - 0.89 7.9 8.3 0.87 8.0 5.7 1.0 1 0 0 1 1 1 0 Reduced folate carrier DDHD PF02862.12 CDI73753.1 - 0.95 9.2 10.2 1 9.1 7.1 1.0 1 0 0 1 1 1 0 DDHD domain FlaG PF03646.10 CDI73753.1 - 0.99 9.5 20.6 1.2 9.2 14.3 1.1 1 0 0 1 1 1 0 FlaG protein RR_TM4-6 PF06459.7 CDI73753.1 - 1.1 9.1 13.3 1.2 9.0 9.2 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Gti1_Pac2 PF09729.4 CDI73753.1 - 1.1 9.1 7.1 1.1 9.0 4.9 1.1 1 0 0 1 1 1 0 Gti1/Pac2 family DUF3535 PF12054.3 CDI73753.1 - 1.1 7.7 12.0 1.1 7.7 8.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3535) DUF4050 PF13259.1 CDI73753.1 - 1.1 9.1 10.0 1.4 8.8 6.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4050) PH_4 PF15404.1 CDI73753.1 - 1.2 8.6 9.9 1.4 8.4 6.9 1.1 1 0 0 1 1 1 0 Pleckstrin homology domain OATP PF03137.15 CDI73753.1 - 1.5 6.7 10.4 1.6 6.7 7.2 1.0 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family RNA_pol_Rpc4 PF05132.9 CDI73753.1 - 1.7 8.6 15.1 1.9 8.5 10.5 1.0 1 0 0 1 1 1 0 RNA polymerase III RPC4 FLO_LFY PF01698.11 CDI73753.1 - 1.7 7.4 11.1 1.6 7.4 7.7 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein FAM176 PF14851.1 CDI73753.1 - 1.9 8.1 6.2 2.2 7.9 4.3 1.1 1 0 0 1 1 1 0 FAM176 family Band_3_cyto PF07565.8 CDI73753.1 - 2 7.8 12.9 1.9 7.9 9.0 1.0 1 0 0 1 1 1 0 Band 3 cytoplasmic domain GvpL_GvpF PF06386.6 CDI73753.1 - 2 7.9 14.4 2.1 7.8 10.0 1.0 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF Zip PF02535.17 CDI73753.1 - 2.1 7.2 4.3 2 7.3 3.0 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter SeqA PF03925.8 CDI73753.1 - 2.2 7.9 11.5 2.3 7.9 8.0 1.0 1 0 0 1 1 1 0 SeqA protein Peroxin-13_N PF04088.8 CDI73753.1 - 2.2 8.2 5.5 2.3 8.1 3.8 1.1 1 0 0 1 1 1 0 Peroxin 13, N-terminal region Suf PF05843.9 CDI73753.1 - 2.3 7.9 21.8 2.5 7.7 15.1 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Baculo_PP31 PF05311.6 CDI73753.1 - 2.3 7.3 14.8 2.5 7.2 10.3 1.0 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) DUF3464 PF11947.3 CDI73753.1 - 2.5 7.5 11.6 2.7 7.4 8.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) RP-C_C PF11800.3 CDI73753.1 - 2.5 7.7 11.4 2.8 7.6 7.9 1.0 1 0 0 1 1 1 0 Replication protein C C-terminal region Pap_E4 PF02711.9 CDI73753.1 - 2.9 8.7 12.7 3.6 8.4 8.8 1.1 1 0 0 1 1 1 0 E4 protein DUF2370 PF10176.4 CDI73753.1 - 2.9 7.1 9.0 3.3 6.9 6.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) Glyco_transf_15 PF01793.11 CDI73753.1 - 3.3 6.5 11.5 3.5 6.4 8.0 1.0 1 0 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase Peptidase_S49_N PF08496.5 CDI73753.1 - 3.4 7.4 11.6 3.4 7.4 8.1 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal NARP1 PF12569.3 CDI73753.1 - 3.5 6.2 12.5 3.6 6.2 8.6 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DUF4557 PF15101.1 CDI73753.1 - 3.5 7.4 23.5 3.5 7.4 16.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) Ctr PF04145.10 CDI73753.1 - 3.5 7.6 7.3 3.6 7.6 5.1 1.1 1 0 0 1 1 1 0 Ctr copper transporter family Pex14_N PF04695.8 CDI73753.1 - 3.6 7.6 22.9 4.2 7.4 15.9 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Tim54 PF11711.3 CDI73753.1 - 3.6 6.0 9.8 4 5.9 6.8 1.0 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DUF4220 PF13968.1 CDI73753.1 - 3.8 6.5 5.4 3.3 6.7 3.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4220) Presenilin PF01080.12 CDI73753.1 - 3.8 6.2 7.0 4 6.1 4.8 1.0 1 0 0 1 1 1 0 Presenilin RIC3 PF15361.1 CDI73753.1 - 3.8 7.7 14.6 4.2 7.5 10.1 1.0 1 0 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 G-alpha PF00503.15 CDI73753.1 - 3.9 6.0 14.0 4.1 5.9 9.7 1.0 1 0 0 1 1 1 0 G-protein alpha subunit EIIBC-GUT_N PF03612.9 CDI73753.1 - 4.1 6.9 10.4 4.3 6.9 7.2 1.1 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus DUF3306 PF11748.3 CDI73753.1 - 4.2 8.0 12.7 4.8 7.8 8.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3306) RED_N PF07808.8 CDI73753.1 - 4.8 6.3 19.9 4.8 6.3 13.8 1.1 1 0 0 1 1 1 0 RED-like protein N-terminal region DUF4199 PF13858.1 CDI73753.1 - 4.8 7.0 8.9 5.3 6.9 6.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) CD20 PF04103.10 CDI73753.1 - 5.1 7.0 5.2 5.3 6.9 3.6 1.2 1 0 0 1 1 1 0 CD20-like family Spore_coat_CotO PF14153.1 CDI73753.1 - 5.2 6.4 19.9 5.7 6.3 13.8 1.0 1 0 0 1 1 1 0 Spore coat protein CotO CPSF100_C PF13299.1 CDI73753.1 - 5.2 7.2 12.2 5.4 7.1 8.5 1.0 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal DUF2201_N PF13203.1 CDI73753.1 - 5.3 6.1 13.4 5.8 5.9 9.3 1.0 1 0 0 1 1 1 0 Putative metallopeptidase domain HGTP_anticodon2 PF12745.2 CDI73753.1 - 5.4 6.0 11.3 5.8 5.9 7.8 1.0 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs DUF3675 PF12428.3 CDI73753.1 - 5.7 7.2 6.5 5.7 7.2 4.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3675) DDRGK PF09756.4 CDI73753.1 - 5.7 6.3 18.8 6.7 6.0 13.0 1.0 1 0 0 1 1 1 0 DDRGK domain WASH-7_C PF14746.1 CDI73753.1 - 5.7 6.5 10.6 6.4 6.3 7.4 1.2 1 0 0 1 1 1 0 WASH complex subunit 7, C-terminal FHIPEP PF00771.15 CDI73753.1 - 5.8 5.1 9.9 6.3 4.9 6.9 1.0 1 0 0 1 1 1 0 FHIPEP family SAGA-Tad1 PF12767.2 CDI73753.1 - 5.8 6.4 16.5 6.3 6.3 11.4 1.1 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit DUF4175 PF13779.1 CDI73753.1 - 5.9 4.4 40.6 6.6 4.3 28.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Glyco_transf_6 PF03414.8 CDI73753.1 - 6 5.2 8.0 5.8 5.2 5.6 1.0 1 0 0 1 1 1 0 Glycosyltransferase family 6 BRF1 PF07741.8 CDI73753.1 - 6.1 7.1 14.3 7.5 6.8 9.9 1.1 1 0 0 1 1 1 0 Brf1-like TBP-binding domain Endonuc_Holl PF10107.4 CDI73753.1 - 6.3 6.4 11.2 6.5 6.4 7.7 1.1 1 0 0 1 1 1 0 Endonuclease related to archaeal Holliday junction resolvase MDFI PF15316.1 CDI73753.1 - 6.3 6.7 7.3 6 6.8 5.0 1.1 1 0 0 1 1 1 0 MyoD family inhibitor DUF106 PF01956.11 CDI73753.1 - 6.5 6.2 13.0 6.6 6.2 9.0 1.0 1 0 0 1 1 1 0 Integral membrane protein DUF106 Herpes_DNAp_acc PF04929.7 CDI73753.1 - 6.5 5.6 9.8 7.1 5.4 6.8 1.0 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Bud13 PF09736.4 CDI73753.1 - 6.6 6.9 18.3 7.6 6.7 12.7 1.1 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex Peptidase_U57 PF05582.7 CDI73753.1 - 6.7 5.5 9.5 7 5.5 6.6 1.0 1 0 0 1 1 1 0 YabG peptidase U57 Sec62 PF03839.11 CDI73753.1 - 6.8 6.0 8.4 7.3 5.9 5.9 1.0 1 0 0 1 1 1 0 Translocation protein Sec62 CRF1 PF10380.4 CDI73753.1 - 7.1 6.9 10.1 7.5 6.9 7.0 1.1 1 0 0 1 1 1 0 Transcription factor CRF1 Neur_chan_memb PF02932.11 CDI73753.1 - 7.2 6.4 7.7 7.8 6.3 5.4 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region CDC45 PF02724.9 CDI73753.1 - 7.3 4.4 11.7 7.7 4.4 8.1 1.0 1 0 0 1 1 1 0 CDC45-like protein eIF3_subunit PF08597.5 CDI73753.1 - 7.4 6.0 14.1 8.1 5.9 9.8 1.0 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit SprA-related PF12118.3 CDI73753.1 - 7.5 5.7 35.5 8.4 5.6 24.6 1.0 1 0 0 1 1 1 0 SprA-related family CagX PF03524.10 CDI73753.1 - 7.7 5.7 12.0 9.8 5.3 8.3 1.3 1 0 0 1 1 1 0 Conjugal transfer protein MRP-S26 PF14943.1 CDI73753.1 - 8.2 5.9 15.9 9.9 5.6 11.0 1.1 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 DUF3276 PF11680.3 CDI73753.1 - 8.3 6.2 8.9 9 6.1 6.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3276) DHHW PF14286.1 CDI73753.1 - 8.6 5.5 10.4 9.2 5.4 7.2 1.0 1 0 0 1 1 1 0 DHHW protein DUF3408 PF11888.3 CDI73753.1 - 9.6 6.1 13.2 11 5.9 9.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) Paramyxo_ncap PF00973.14 CDI73753.1 - 9.8 4.7 9.0 10 4.7 6.3 1.0 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein POM121 PF15229.1 CDI73754.1 - 0.026 13.9 5.5 0.029 13.7 3.8 1.1 1 0 0 1 1 1 0 POM121 family Band_3_cyto PF07565.8 CDI73755.1 - 0.00065 19.2 4.3 0.00079 19.0 3.0 1.2 1 0 0 1 1 1 1 Band 3 cytoplasmic domain Pex14_N PF04695.8 CDI73755.1 - 0.0011 18.9 12.9 0.0011 18.9 9.0 1.5 2 0 0 2 2 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Gti1_Pac2 PF09729.4 CDI73755.1 - 0.0027 17.6 0.4 0.0028 17.5 0.3 1.1 1 0 0 1 1 1 1 Gti1/Pac2 family Peptidase_U57 PF05582.7 CDI73755.1 - 0.0096 14.9 3.2 0.011 14.6 2.2 1.1 1 0 0 1 1 1 1 YabG peptidase U57 Serinc PF03348.10 CDI73755.1 - 0.011 14.4 4.6 0.015 14.0 3.2 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) Otopetrin PF03189.8 CDI73755.1 - 0.014 14.4 0.1 0.014 14.4 0.0 1.1 1 0 0 1 1 1 0 Otopetrin Peroxin-13_N PF04088.8 CDI73755.1 - 0.032 14.1 3.1 0.053 13.4 2.1 1.3 1 0 0 1 1 1 0 Peroxin 13, N-terminal region Neur_chan_memb PF02932.11 CDI73755.1 - 0.038 13.8 1.2 0.04 13.7 0.8 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF2370 PF10176.4 CDI73755.1 - 0.042 13.1 2.0 0.078 12.3 1.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) FimP PF09766.4 CDI73755.1 - 0.075 12.0 20.3 0.1 11.6 14.1 1.1 1 0 0 1 1 1 0 Fms-interacting protein CRF1 PF10380.4 CDI73755.1 - 0.076 13.3 2.5 0.097 13.0 1.7 1.2 1 0 0 1 1 1 0 Transcription factor CRF1 DUF3306 PF11748.3 CDI73755.1 - 0.079 13.6 11.9 0.097 13.3 5.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3306) Zip PF02535.17 CDI73755.1 - 0.11 11.5 3.6 0.18 10.8 2.5 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter Glyco_transf_15 PF01793.11 CDI73755.1 - 0.13 11.1 6.7 0.16 10.8 4.7 1.1 1 0 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase FAM176 PF14851.1 CDI73755.1 - 0.14 11.8 3.5 0.27 10.8 2.4 1.4 1 0 0 1 1 1 0 FAM176 family Suf PF05843.9 CDI73755.1 - 0.15 11.7 12.1 0.23 11.1 8.4 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) SeqA PF03925.8 CDI73755.1 - 0.18 11.4 10.2 0.31 10.7 7.1 1.3 1 0 0 1 1 1 0 SeqA protein OATP PF03137.15 CDI73755.1 - 0.19 9.7 6.9 0.26 9.2 4.8 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Ctr PF04145.10 CDI73755.1 - 0.23 11.5 6.7 0.53 10.3 4.7 1.6 1 0 0 1 1 1 0 Ctr copper transporter family DUF106 PF01956.11 CDI73755.1 - 0.29 10.6 4.8 0.45 10.0 3.3 1.3 1 0 0 1 1 1 0 Integral membrane protein DUF106 CPSF100_C PF13299.1 CDI73755.1 - 0.33 11.1 8.1 0.54 10.4 5.6 1.3 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal EcsC PF12787.2 CDI73755.1 - 0.35 10.2 11.8 0.36 10.1 5.2 2.0 2 0 0 2 2 2 0 EcsC protein family Pap_E4 PF02711.9 CDI73755.1 - 0.36 11.6 11.2 0.59 10.9 7.8 1.3 1 0 0 1 1 1 0 E4 protein SpoVR PF04293.8 CDI73755.1 - 0.62 8.3 10.2 0.79 8.0 7.0 1.1 1 0 0 1 1 1 0 SpoVR like protein DDHD PF02862.12 CDI73755.1 - 0.84 9.3 10.5 1.2 8.9 7.3 1.1 1 0 0 1 1 1 0 DDHD domain FHIPEP PF00771.15 CDI73755.1 - 1.5 7.0 7.0 2.1 6.5 4.9 1.2 1 0 0 1 1 1 0 FHIPEP family DUF4557 PF15101.1 CDI73755.1 - 1.6 8.4 24.2 2.3 7.9 16.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) DUF1266 PF06889.6 CDI73755.1 - 2.1 8.1 10.5 4.1 7.1 7.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1266) Ycf1 PF05758.7 CDI73755.1 - 2.4 5.7 10.6 0.04 11.6 2.9 1.3 2 0 0 2 2 2 0 Ycf1 Spore_coat_CotO PF14153.1 CDI73755.1 - 2.5 7.4 18.1 3.7 6.9 12.5 1.1 1 0 0 1 1 1 0 Spore coat protein CotO AIF_C PF14721.1 CDI73755.1 - 2.8 8.1 11.1 4.6 7.5 7.7 1.2 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term DUF1764 PF08576.5 CDI73755.1 - 2.8 8.7 13.3 4.4 8.1 9.2 1.2 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) DUF2126 PF09899.4 CDI73755.1 - 2.8 5.8 8.1 3.6 5.5 5.6 1.1 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) FLO_LFY PF01698.11 CDI73755.1 - 3.4 6.4 11.2 4.7 5.9 7.8 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein Herpes_glycop PF01528.11 CDI73755.1 - 3.4 6.2 4.7 6.3 5.3 3.3 1.4 1 0 0 1 1 1 0 Herpesvirus glycoprotein M Folate_carrier PF01770.13 CDI73755.1 - 3.5 6.0 12.0 0.23 9.9 4.6 1.6 2 0 0 2 2 2 0 Reduced folate carrier EIIBC-GUT_N PF03612.9 CDI73755.1 - 3.7 7.1 9.1 6 6.4 6.3 1.3 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus DUF912 PF06024.7 CDI73755.1 - 5.6 7.0 7.3 11 6.0 5.1 1.5 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Trp_oprn_chp PF09534.5 CDI73755.1 - 5.7 6.5 22.6 0.047 13.3 2.2 3.0 1 1 1 2 2 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) RR_TM4-6 PF06459.7 CDI73755.1 - 5.9 6.7 12.2 9.4 6.0 8.5 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Hid1 PF12722.2 CDI73755.1 - 6 4.4 13.7 7.5 4.0 9.5 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein LIM_bind PF01803.11 CDI73755.1 - 6.7 5.7 16.5 9.7 5.2 11.4 1.1 1 0 0 1 1 1 0 LIM-domain binding protein FAM91_C PF14648.1 CDI73755.1 - 7.2 5.3 7.2 50 2.5 5.3 1.8 2 0 0 2 2 2 0 FAM91 C-terminus Anoctamin PF04547.7 CDI73755.1 - 7.9 4.9 6.7 11 4.5 4.7 1.1 1 0 0 1 1 1 0 Calcium-activated chloride channel TFIIA PF03153.8 CDI73755.1 - 8 6.2 26.3 0.34 10.7 14.5 1.3 2 0 0 2 2 1 0 Transcription factor IIA, alpha/beta subunit Endonuc_Holl PF10107.4 CDI73755.1 - 8.3 6.0 12.9 12 5.5 8.9 1.2 1 0 0 1 1 1 0 Endonuclease related to archaeal Holliday junction resolvase PAT1 PF09770.4 CDI73755.1 - 8.7 4.4 34.7 11 4.0 24.0 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF4446 PF14584.1 CDI73755.1 - 8.7 6.1 8.0 15 5.3 5.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) FAM60A PF15396.1 CDI73755.1 - 9.7 5.8 9.8 16 5.1 6.8 1.3 1 0 0 1 1 1 0 Protein Family FAM60A Ribosomal_60s PF00428.14 CDI73756.1 - 0.0068 16.7 1.5 0.012 16.0 1.1 1.4 1 0 0 1 1 1 1 60s Acidic ribosomal protein DUF1980 PF09323.5 CDI73756.1 - 0.032 13.9 0.6 0.032 13.9 0.4 3.1 1 1 2 3 3 3 0 Domain of unknown function (DUF1980) Macoilin PF09726.4 CDI73756.1 - 0.21 9.8 41.8 0.33 9.1 29.0 1.2 1 0 0 1 1 1 0 Transmembrane protein DUF1510 PF07423.6 CDI73756.1 - 0.76 9.1 41.6 5.3 6.3 25.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) Utp14 PF04615.8 CDI73756.1 - 1 7.4 48.2 1.3 7.0 33.4 1.1 1 0 0 1 1 1 0 Utp14 protein DUF572 PF04502.8 CDI73756.1 - 7.3 5.7 44.3 9.3 5.3 30.7 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Herpes_env PF01673.13 CDI73756.1 - 7.7 4.9 34.9 9.9 4.5 24.2 1.1 1 0 0 1 1 1 0 Herpesvirus putative major envelope glycoprotein Ycf1 PF05758.7 CDI73757.1 - 6.6 4.3 45.4 0.11 10.2 8.6 4.3 4 0 0 4 4 4 0 Ycf1 CDC45 PF02724.9 CDI73758.1 - 0.0003 18.9 11.6 0.0003 18.9 8.0 2.2 2 0 0 2 2 2 1 CDC45-like protein Suf PF05843.9 CDI73758.1 - 0.0011 18.7 11.5 0.0011 18.7 8.0 3.1 2 1 1 3 3 1 1 Suppressor of forked protein (Suf) Cwf_Cwc_15 PF04889.7 CDI73758.1 - 0.0027 17.4 5.5 0.0027 17.4 3.8 3.1 3 1 0 3 3 2 1 Cwf15/Cwc15 cell cycle control protein MRP-S26 PF14943.1 CDI73758.1 - 0.0066 16.0 7.9 0.0066 16.0 5.5 3.0 2 1 0 2 2 1 1 Mitochondrial ribosome subunit S26 DUF4175 PF13779.1 CDI73758.1 - 0.012 13.3 93.3 0.006 14.3 12.6 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4175) Med15 PF09606.5 CDI73758.1 - 0.078 11.1 123.1 0.1 10.7 85.3 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal SDA1 PF05285.7 CDI73758.1 - 0.25 10.5 32.5 0.076 12.2 4.4 2.2 2 0 0 2 2 2 0 SDA1 DUF92 PF01940.11 CDI73758.1 - 0.3 10.1 13.6 0.31 10.1 0.8 2.3 2 0 0 2 2 2 0 Integral membrane protein DUF92 SOBP PF15279.1 CDI73758.1 - 0.47 10.7 49.1 0.27 11.5 10.1 2.1 2 0 0 2 2 2 0 Sine oculis-binding protein SRP-alpha_N PF04086.8 CDI73758.1 - 0.69 9.2 39.0 0.073 12.4 5.6 2.2 2 0 0 2 2 2 0 Signal recognition particle, alpha subunit, N-terminal Utp14 PF04615.8 CDI73758.1 - 0.71 7.9 52.9 1.2 7.2 11.9 2.0 2 0 0 2 2 2 0 Utp14 protein TT_ORF1 PF02956.9 CDI73758.1 - 0.86 7.9 27.6 0.93 7.8 8.8 2.2 2 0 0 2 2 2 0 TT viral orf 1 Zip PF02535.17 CDI73758.1 - 0.97 8.3 23.0 0.059 12.3 2.0 2.3 2 0 0 2 2 2 0 ZIP Zinc transporter DUF4614 PF15391.1 CDI73758.1 - 1.1 9.0 44.1 0.041 13.6 12.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4614) SAPS PF04499.10 CDI73758.1 - 2.6 6.5 34.7 1.1 7.8 11.4 2.1 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein DUF4551 PF15087.1 CDI73758.1 - 6.8 4.9 40.6 1.3 7.3 9.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4551) DUF4045 PF13254.1 CDI73758.1 - 6.9 5.8 49.6 1.7 7.8 11.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4045) LRR_4 PF12799.2 CDI73759.1 - 2.6e-28 97.1 46.9 3e-06 26.7 1.0 9.5 5 2 4 10 10 10 9 Leucine Rich repeats (2 copies) LRR_9 PF14580.1 CDI73759.1 - 3.6e-23 82.0 0.9 3.9e-13 49.3 0.0 4.5 3 1 0 4 4 4 3 Leucine-rich repeat LRR_8 PF13855.1 CDI73759.1 - 2.9e-21 74.9 41.7 6.3e-06 25.8 1.5 8.7 6 1 2 8 8 8 6 Leucine rich repeat LRR_1 PF00560.28 CDI73759.1 - 2.3e-07 29.8 42.3 0.36 11.0 0.0 11.3 12 0 0 12 12 12 5 Leucine Rich Repeat LRR_6 PF13516.1 CDI73759.1 - 6.4e-06 25.7 23.3 4 7.8 0.1 9.8 7 1 1 8 8 8 3 Leucine Rich repeat LRR_7 PF13504.1 CDI73759.1 - 0.07 13.3 46.9 3.6 8.1 0.1 12.1 14 0 0 14 14 14 0 Leucine rich repeat LRR_4 PF12799.2 CDI73760.1 - 6.7e-13 47.9 10.2 1.9e-06 27.3 0.0 3.7 3 1 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CDI73760.1 - 4.1e-08 32.8 11.6 5e-05 22.9 2.9 2.4 2 0 0 2 2 2 2 Leucine rich repeat LRR_6 PF13516.1 CDI73760.1 - 0.12 12.5 8.0 38 4.7 0.0 5.0 5 1 0 5 5 5 0 Leucine Rich repeat LRR_9 PF14580.1 CDI73760.1 - 0.75 9.3 1.5 6.7 6.2 0.2 2.2 2 0 0 2 2 2 0 Leucine-rich repeat LRR_1 PF00560.28 CDI73760.1 - 1.3 9.3 12.2 17 5.9 0.0 5.3 4 1 0 4 4 4 0 Leucine Rich Repeat Dynein_heavy PF03028.10 CDI73763.1 - 1.3e-223 744.0 0.0 5.2e-223 742.0 0.0 1.9 2 0 0 2 2 2 1 Dynein heavy chain and region D6 of dynein motor AAA_9 PF12781.2 CDI73763.1 - 8.4e-85 283.2 1.2 2.2e-81 272.0 0.1 2.3 1 1 1 2 2 2 2 ATP-binding dynein motor region D5 MT PF12777.2 CDI73763.1 - 1.4e-14 53.6 0.1 2.6e-14 52.7 0.0 1.4 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor EF-hand_1 PF00036.27 CDI73766.1 - 3.1e-31 104.2 2.1 3.3e-07 29.1 0.0 4.4 4 0 0 4 4 4 4 EF hand EF-hand_5 PF13202.1 CDI73766.1 - 3.2e-28 95.7 5.0 1.1e-07 30.8 0.1 5.1 5 0 0 5 5 5 4 EF hand EF-hand_7 PF13499.1 CDI73766.1 - 4.3e-25 87.6 0.8 7.9e-12 45.1 0.1 3.1 3 1 0 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.1 CDI73766.1 - 4.9e-24 82.0 2.1 9e-06 25.1 0.0 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.1 CDI73766.1 - 1.3e-19 69.5 0.4 2.2e-06 27.2 0.1 4.3 3 1 1 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.4 CDI73766.1 - 6.7e-09 35.7 0.5 0.00032 20.7 0.0 3.0 3 0 0 3 3 3 2 Secreted protein acidic and rich in cysteine Ca binding region Pkinase PF00069.20 CDI73766.1 - 1.9e-08 33.8 0.0 2.8e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain EF-hand_4 PF12763.2 CDI73766.1 - 3.1e-08 33.2 0.7 0.0026 17.4 0.1 2.4 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand Excalibur PF05901.6 CDI73766.1 - 0.033 14.5 0.8 37 4.7 0.0 3.5 3 0 0 3 3 3 0 Excalibur calcium-binding domain EF-hand_10 PF14788.1 CDI73766.1 - 0.057 13.0 0.0 6.5 6.5 0.0 3.3 3 0 0 3 3 3 0 EF hand Cyto_ox_2 PF02322.10 CDI73767.1 - 0.03 13.5 7.7 0.045 12.9 5.3 1.2 1 0 0 1 1 1 0 Cytochrome oxidase subunit II ETRAMP PF09716.5 CDI73767.1 - 0.17 11.8 0.3 0.17 11.8 0.2 4.5 4 2 2 6 6 6 0 Malarial early transcribed membrane protein (ETRAMP) CD20 PF04103.10 CDI73768.1 - 0.0062 16.4 0.4 0.0062 16.4 0.3 4.1 2 1 0 2 2 2 1 CD20-like family IncA PF04156.9 CDI73768.1 - 0.008 15.7 8.9 0.008 15.7 6.2 3.2 3 1 0 3 3 3 1 IncA protein Ribosomal_60s PF00428.14 CDI73769.1 - 0.025 14.9 5.9 0.031 14.6 4.1 1.3 1 0 0 1 1 1 0 60s Acidic ribosomal protein Abhydrolase_5 PF12695.2 CDI73769.1 - 0.059 13.1 1.2 0.068 12.9 0.8 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase family Pribosyl_synth PF14572.1 CDI73769.1 - 0.29 10.8 2.4 0.36 10.5 1.6 1.3 1 1 0 1 1 1 0 Phosphoribosyl synthetase-associated domain Band_3_cyto PF07565.8 CDI73769.1 - 0.45 9.9 11.7 0.59 9.5 8.1 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain GPCR_chapero_1 PF11904.3 CDI73769.1 - 1 8.4 9.4 1.2 8.2 6.5 1.1 1 0 0 1 1 1 0 GPCR-chaperone DUF2413 PF10310.4 CDI73769.1 - 1.9 7.1 18.5 2.2 7.0 12.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) SPX PF03105.14 CDI73769.1 - 2.6 7.7 11.3 3 7.5 7.8 1.1 1 0 0 1 1 1 0 SPX domain DUF966 PF06136.8 CDI73769.1 - 6.8 5.9 12.7 8.2 5.7 8.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF966) DUF819 PF05684.7 CDI73770.1 - 0.028 13.2 3.1 0.041 12.6 2.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF819) DUF4220 PF13968.1 CDI73770.1 - 0.028 13.5 4.9 0.034 13.2 3.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4220) Chorion_2 PF03964.10 CDI73770.1 - 0.04 14.4 6.7 0.08 13.4 4.6 1.6 1 0 0 1 1 1 0 Chorion family 2 Mem_trans PF03547.13 CDI73770.1 - 0.052 11.8 3.4 0.063 11.5 2.4 1.1 1 0 0 1 1 1 0 Membrane transport protein Methyltransf_14 PF08484.6 CDI73770.1 - 0.24 10.9 3.8 0.34 10.4 2.6 1.2 1 0 0 1 1 1 0 C-methyltransferase C-terminal domain DUF543 PF04418.7 CDI73770.1 - 0.35 10.8 1.5 1.3 9.0 1.1 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF543) Plasmodium_Vir PF05795.6 CDI73770.1 - 0.43 9.7 3.0 0.48 9.5 2.1 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein TT_ORF1 PF02956.9 CDI73770.1 - 0.49 8.7 11.5 0.67 8.3 7.9 1.1 1 0 0 1 1 1 0 TT viral orf 1 DUF3899 PF13038.1 CDI73770.1 - 0.51 10.5 2.4 3.8 7.7 0.3 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3899) Peptidase_S64 PF08192.6 CDI73770.1 - 0.68 8.1 12.0 0.81 7.9 8.3 1.1 1 0 0 1 1 1 0 Peptidase family S64 Gti1_Pac2 PF09729.4 CDI73770.1 - 0.73 9.6 8.6 1.2 8.9 6.0 1.4 1 0 0 1 1 1 0 Gti1/Pac2 family TAF4 PF05236.9 CDI73770.1 - 1 8.5 29.2 1.8 7.7 19.7 1.8 1 1 1 2 2 2 0 Transcription initiation factor TFIID component TAF4 family SOBP PF15279.1 CDI73770.1 - 1.1 9.6 18.5 1.4 9.1 12.8 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein DUF2217 PF10265.4 CDI73770.1 - 1.1 7.8 12.3 1.4 7.5 8.5 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) Dapper PF15268.1 CDI73770.1 - 1.5 7.5 29.3 1.9 7.1 20.3 1.1 1 0 0 1 1 1 0 Dapper TFIIA PF03153.8 CDI73770.1 - 3.3 7.5 36.8 4.7 6.9 25.5 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Ycf1 PF05758.7 CDI73770.1 - 3.8 5.0 14.4 5.1 4.6 10.0 1.1 1 0 0 1 1 1 0 Ycf1 DUF3373 PF11853.3 CDI73770.1 - 4.8 5.5 12.8 7.4 4.9 8.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) SPX PF03105.14 CDI73770.1 - 6.4 6.4 15.4 8.8 6.0 10.7 1.2 1 0 0 1 1 1 0 SPX domain zf-DHHC PF01529.15 CDI73771.1 - 0.00011 21.6 0.3 0.00018 20.9 0.2 1.3 1 0 0 1 1 1 1 DHHC palmitoyltransferase DUF913 PF06025.7 CDI73771.1 - 0.062 12.0 2.7 0.065 11.9 1.9 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Herpes_DNAp_acc PF04929.7 CDI73771.1 - 0.2 10.5 13.1 0.23 10.3 9.1 1.0 1 0 0 1 1 1 0 Herpes DNA replication accessory factor DUF605 PF04652.11 CDI73771.1 - 0.35 10.2 18.6 0.33 10.3 12.9 1.0 1 0 0 1 1 1 0 Vta1 like PAT1 PF09770.4 CDI73771.1 - 0.65 8.1 35.0 0.69 8.0 24.2 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Gag_spuma PF03276.9 CDI73771.1 - 0.81 7.9 29.2 0.89 7.8 20.2 1.1 1 0 0 1 1 1 0 Spumavirus gag protein Tim54 PF11711.3 CDI73771.1 - 0.92 8.0 12.3 1.1 7.7 8.5 1.0 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 FAM176 PF14851.1 CDI73771.1 - 1.1 8.9 9.6 1.5 8.4 6.7 1.2 1 0 0 1 1 1 0 FAM176 family Peptidase_U57 PF05582.7 CDI73771.1 - 1.1 8.1 13.6 1.2 7.9 9.4 1.0 1 0 0 1 1 1 0 YabG peptidase U57 NPR3 PF03666.8 CDI73771.1 - 1.7 7.0 16.6 2 6.8 11.5 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 RR_TM4-6 PF06459.7 CDI73771.1 - 2 8.2 19.3 2.6 7.8 13.4 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 AUX_IAA PF02309.11 CDI73771.1 - 2.3 7.9 14.3 2.9 7.5 9.9 1.1 1 0 0 1 1 1 0 AUX/IAA family CPSF100_C PF13299.1 CDI73771.1 - 6 7.0 16.3 7.1 6.7 11.3 1.1 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal MMR1 PF08505.5 CDI73771.1 - 6.6 6.6 21.4 7 6.6 14.8 1.0 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein Suf PF05843.9 CDI73771.1 - 9.3 5.8 22.3 16 5.0 15.5 1.4 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Spt20 PF12090.3 CDI73772.1 - 0.018 14.3 0.7 0.023 14.0 0.5 1.3 1 0 0 1 1 1 0 Spt20 family DUF4131 PF13567.1 CDI73772.1 - 0.054 12.8 0.0 0.075 12.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) VIT1 PF01988.14 CDI73772.1 - 0.16 11.4 6.0 0.35 10.3 4.2 1.6 1 0 0 1 1 1 0 VIT family RAB3GAP2_N PF14655.1 CDI73772.1 - 0.27 10.1 6.3 0.4 9.6 4.4 1.2 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Med15 PF09606.5 CDI73772.1 - 0.28 9.3 23.9 0.41 8.7 16.5 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Claudin_2 PF13903.1 CDI73772.1 - 0.36 10.5 1.8 0.56 9.8 1.3 1.2 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction DUF4231 PF14015.1 CDI73772.1 - 1.1 9.3 4.8 2.4 8.1 1.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) PAT1 PF09770.4 CDI73772.1 - 4.9 5.2 27.8 5.7 5.0 19.2 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Corona_nucleoca PF00937.13 CDI73773.1 - 0.33 9.8 28.7 0.38 9.6 19.9 1.1 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein Serinc PF03348.10 CDI73773.1 - 0.62 8.7 11.4 0.64 8.6 7.9 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) CAF-1_p150 PF11600.3 CDI73773.1 - 0.65 9.3 34.2 0.063 12.6 20.8 1.5 1 1 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal BTV_NS2 PF04514.7 CDI73773.1 - 1.7 7.4 11.6 1.7 7.4 8.0 1.2 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 LMBR1 PF04791.11 CDI73773.1 - 5.4 5.4 14.5 5.7 5.4 10.1 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Peptidase_S49_N PF08496.5 CDI73773.1 - 8.5 6.1 21.0 1.6 8.5 11.6 1.8 2 0 0 2 2 2 0 Peptidase family S49 N-terminal PcfK PF14058.1 CDI73773.1 - 9 6.4 23.8 1.2 9.2 13.6 1.6 1 1 1 2 2 2 0 PcfK-like protein BAF1_ABF1 PF04684.8 CDI73775.1 - 0.0015 17.4 20.1 0.0015 17.4 13.9 3.0 1 1 2 3 3 3 1 BAF1 / ABF1 chromatin reorganising factor DUF755 PF05501.6 CDI73775.1 - 0.01 15.8 18.9 0.01 15.8 13.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF755) Chorion_2 PF03964.10 CDI73775.1 - 0.021 15.3 5.6 0.021 15.3 3.9 2.4 2 1 0 2 2 2 0 Chorion family 2 RAP1 PF07218.6 CDI73775.1 - 0.35 8.9 3.5 0.42 8.6 2.4 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) AMP-binding PF00501.23 CDI73775.1 - 2 6.7 10.8 0.76 8.0 5.9 1.4 1 1 0 1 1 1 0 AMP-binding enzyme DUF4604 PF15377.1 CDI73775.1 - 6.9 6.8 33.7 5.4 7.2 4.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4604) SOBP PF15279.1 CDI73775.1 - 7.4 6.8 37.9 12 6.2 26.3 1.4 1 0 0 1 1 1 0 Sine oculis-binding protein TerC PF03741.11 CDI73776.1 - 7.8 5.8 6.4 0.62 9.4 0.1 2.0 1 1 1 2 2 2 0 Integral membrane protein TerC family SOBP PF15279.1 CDI73777.1 - 1.7 8.9 5.0 1.9 8.7 3.5 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein Peptidase_S64 PF08192.6 CDI73777.1 - 5.1 5.3 15.3 5.3 5.2 10.6 1.1 1 0 0 1 1 1 0 Peptidase family S64 Utp14 PF04615.8 CDI73777.1 - 8.1 4.4 14.3 9.4 4.2 9.9 1.0 1 0 0 1 1 1 0 Utp14 protein Herpes_BLLF1 PF05109.8 CDI73777.1 - 8.8 4.1 33.7 12 3.7 23.4 1.1 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) tRNA_bind PF01588.15 CDI73780.1 - 4.1e-25 87.4 0.0 1e-24 86.1 0.0 1.7 2 0 0 2 2 2 1 Putative tRNA binding domain BAF1_ABF1 PF04684.8 CDI73780.1 - 6.6e-06 25.2 11.4 9.1e-06 24.7 7.9 1.1 1 0 0 1 1 1 1 BAF1 / ABF1 chromatin reorganising factor GST_C_3 PF14497.1 CDI73780.1 - 0.0023 18.3 0.0 0.0048 17.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Topoisom_I_N PF02919.10 CDI73780.1 - 0.062 12.5 1.0 0.094 11.9 0.7 1.2 1 0 0 1 1 1 0 Eukaryotic DNA topoisomerase I, DNA binding fragment GST_C_2 PF13410.1 CDI73780.1 - 0.063 13.1 0.0 0.18 11.7 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Med15 PF09606.5 CDI73780.1 - 0.073 11.2 13.5 0.093 10.9 9.4 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal GST_C PF00043.20 CDI73780.1 - 0.1 12.5 0.0 0.22 11.5 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Activator_LAG-3 PF11498.3 CDI73780.1 - 0.72 8.5 22.1 1 8.0 15.3 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Androgen_recep PF02166.11 CDI73780.1 - 4.1 6.1 9.1 6.2 5.5 6.3 1.2 1 0 0 1 1 1 0 Androgen receptor DivIC PF04977.10 CDI73780.1 - 4.9 6.7 9.1 9.9 5.7 6.3 1.4 1 0 0 1 1 1 0 Septum formation initiator Med3 PF11593.3 CDI73780.1 - 9.5 5.3 24.0 0.027 13.7 9.4 1.8 1 1 1 2 2 2 0 Mediator complex subunit 3 fungal YL1 PF05764.8 CDI73781.1 - 0.27 10.8 37.4 0.27 10.7 25.9 1.0 1 0 0 1 1 1 0 YL1 nuclear protein Nop53 PF07767.6 CDI73781.1 - 0.87 8.5 35.9 0.89 8.4 24.9 1.0 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Nop14 PF04147.7 CDI73781.1 - 0.99 7.2 37.3 1.1 7.1 25.8 1.0 1 0 0 1 1 1 0 Nop14-like family ERF PF04404.7 CDI73781.1 - 2.4 7.6 19.6 2.8 7.4 13.6 1.1 1 0 0 1 1 1 0 ERF superfamily LZ_Tnp_IS66 PF13007.2 CDI73781.1 - 3.8 8.2 18.6 5 7.8 12.9 1.3 1 0 0 1 1 1 0 Transposase C of IS166 homeodomain Spt5_N PF11942.3 CDI73781.1 - 4.9 7.8 32.2 6.5 7.4 22.4 1.3 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal RNase_H2-Ydr279 PF09468.5 CDI73781.1 - 7.1 5.7 29.9 7.3 5.6 20.7 1.0 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) YqfQ PF14181.1 CDI73781.1 - 9.8 6.1 28.9 10 6.1 20.0 1.1 1 0 0 1 1 1 0 YqfQ-like protein DUF3355 PF11835.3 CDI73783.1 - 0.045 13.5 1.2 0.11 12.2 0.8 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF3355) FAM104 PF15434.1 CDI73783.1 - 0.4 10.9 2.6 0.94 9.7 1.8 1.8 1 1 0 1 1 1 0 Family 104 Tmemb_cc2 PF10267.4 CDI73784.1 - 0.11 11.1 0.2 0.16 10.5 0.1 1.3 1 1 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein IncA PF04156.9 CDI73784.1 - 1.4 8.4 4.0 1.8 8.1 2.8 1.4 1 1 0 1 1 1 0 IncA protein OmpH PF03938.9 CDI73785.1 - 0.0039 17.1 10.6 0.0039 17.1 7.4 5.3 3 2 1 4 4 4 1 Outer membrane protein (OmpH-like) COPI_assoc PF08507.5 CDI73786.1 - 0.017 14.7 0.1 0.017 14.7 0.1 3.2 2 1 0 2 2 2 0 COPI associated protein PAT1 PF09770.4 CDI73787.1 - 9.9 4.2 60.9 0.32 9.1 36.7 2.0 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 EF-hand_4 PF12763.2 CDI73789.1 - 0.018 14.7 0.0 0.031 14.0 0.0 1.3 1 0 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand DUF4367 PF14285.1 CDI73790.1 - 0.005 16.1 2.4 1.2 8.3 0.1 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF4367) DUF202 PF02656.10 CDI73790.1 - 0.39 10.9 6.0 3.9 7.7 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF202) DUF966 PF06136.8 CDI73790.1 - 0.47 9.8 26.8 0.71 9.2 18.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF966) DUF2899 PF11449.3 CDI73790.1 - 0.62 9.1 5.1 0.23 10.6 0.5 1.9 1 1 0 2 2 2 0 Protein of unknown function (DUF2899) Afi1 PF07792.7 CDI73790.1 - 0.67 9.9 24.2 0.6 10.1 3.2 2.5 1 1 1 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Ldh_1_N PF00056.18 CDI73790.1 - 1.2 8.9 5.6 1.2 9.0 0.2 2.2 2 0 0 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain PAT1 PF09770.4 CDI73790.1 - 2.9 6.0 32.2 3.7 5.6 22.3 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Presenilin PF01080.12 CDI73790.1 - 2.9 6.6 17.7 0.064 12.0 4.7 2.1 1 1 1 2 2 2 0 Presenilin LAP1C PF05609.7 CDI73790.1 - 3.4 6.2 24.0 4.1 5.9 14.2 1.9 1 1 1 2 2 2 0 Lamina-associated polypeptide 1C (LAP1C) zf-A20 PF01754.11 CDI73791.1 - 1.7e-23 81.7 20.3 1.3e-11 43.7 4.3 2.4 2 0 0 2 2 2 2 A20-like zinc finger NMD3 PF04981.8 CDI73791.1 - 0.016 14.3 1.5 2.6 7.1 0.1 2.3 2 0 0 2 2 2 0 NMD3 family DUF164 PF02591.10 CDI73791.1 - 1.1 9.1 12.3 3.2 7.6 0.7 3.3 3 0 0 3 3 3 0 Putative zinc ribbon domain PRTP PF01366.13 CDI73791.1 - 2.3 6.1 12.0 2.8 5.8 1.5 2.4 2 0 0 2 2 2 0 Herpesvirus processing and transport protein PUB PF09409.5 CDI73793.1 - 3.6e-12 45.8 0.0 8.5e-12 44.6 0.0 1.6 1 0 0 1 1 1 1 PUB domain NIL PF09383.5 CDI73793.1 - 0.078 12.5 2.8 0.36 10.4 0.0 2.8 3 0 0 3 3 3 0 NIL domain OmpH PF03938.9 CDI73793.1 - 0.43 10.5 18.6 0.71 9.7 12.9 1.5 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) V_ATPase_I PF01496.14 CDI73793.1 - 0.81 7.4 7.1 0.84 7.4 4.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4613 PF15390.1 CDI73793.1 - 2.1 6.4 6.6 2.5 6.1 4.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) CAF-1_p150 PF11600.3 CDI73793.1 - 2.7 7.3 31.5 4.9 6.4 21.8 1.4 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Oxysterol_BP PF01237.13 CDI73793.1 - 7.2 4.9 10.2 8.6 4.7 7.0 1.2 1 0 0 1 1 1 0 Oxysterol-binding protein AAA_23 PF13476.1 CDI73793.1 - 8.8 6.5 13.0 16 5.7 9.0 1.4 1 0 0 1 1 1 0 AAA domain SRRM_C PF15230.1 CDI73794.1 - 2.1 8.4 9.6 5.7 7.1 6.7 1.7 1 0 0 1 1 1 0 Serine/arginine repetitive matrix protein C-terminus APG6 PF04111.7 CDI73795.1 - 4.4e-08 32.5 1.9 4.4e-08 32.5 1.3 1.5 2 0 0 2 2 2 1 Autophagy protein Apg6 DUF1192 PF06698.6 CDI73795.1 - 0.05 13.4 1.9 0.12 12.2 1.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) DUF4391 PF14335.1 CDI73795.1 - 0.051 12.9 0.3 0.075 12.4 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4391) Macoilin PF09726.4 CDI73795.1 - 0.2 9.8 6.9 0.33 9.1 4.8 1.3 1 0 0 1 1 1 0 Transmembrane protein DUF3613 PF12266.3 CDI73795.1 - 0.39 10.2 5.2 3.6 7.1 0.5 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3613) SpaB_C PF14028.1 CDI73795.1 - 4.1 6.8 10.8 15 4.9 7.5 1.8 1 1 0 1 1 1 0 SpaB C-terminal domain APG6 PF04111.7 CDI73796.1 - 1.8e-17 63.3 0.2 6.2e-17 61.6 0.1 1.7 1 1 0 1 1 1 1 Autophagy protein Apg6 Metallophos PF00149.23 CDI73798.1 - 0.0015 17.9 0.3 0.094 12.1 0.0 2.3 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase TPT PF03151.11 CDI73799.1 - 0.053 13.1 10.2 0.06 13.0 1.8 2.4 2 0 0 2 2 2 0 Triose-phosphate Transporter family SPX PF03105.14 CDI73800.1 - 0.00017 21.4 0.0 0.0008 19.2 0.0 2.1 1 1 1 2 2 2 1 SPX domain AAA_13 PF13166.1 CDI73800.1 - 0.00042 18.9 8.2 0.00042 18.9 5.7 2.5 2 0 0 2 2 2 1 AAA domain RILP PF11461.3 CDI73800.1 - 0.0031 17.6 7.3 0.11 12.6 0.0 3.4 3 0 0 3 3 3 2 Rab interacting lysosomal protein Phage_GP20 PF06810.6 CDI73800.1 - 0.0033 16.8 0.5 0.0033 16.8 0.4 5.6 4 2 1 6 6 6 1 Phage minor structural protein GP20 Sec8_exocyst PF04048.9 CDI73800.1 - 0.0039 16.8 4.5 0.0039 16.8 3.1 3.3 4 0 0 4 4 4 1 Sec8 exocyst complex component specific domain NPV_P10 PF05531.7 CDI73800.1 - 0.19 11.9 7.0 7.2 6.9 0.0 4.8 4 1 1 5 5 5 0 Nucleopolyhedrovirus P10 protein DUF342 PF03961.8 CDI73800.1 - 8.3 4.6 28.6 0.4 9.0 1.7 3.5 1 1 0 3 3 3 0 Protein of unknown function (DUF342) N6_N4_Mtase PF01555.13 CDI73802.1 - 0.028 13.8 0.1 5.5 6.4 0.0 3.1 2 2 1 3 3 3 0 DNA methylase Shadoo PF14999.1 CDI73803.1 - 0.092 12.5 1.2 0.13 12.1 0.8 1.2 1 0 0 1 1 1 0 Shadow of prion protein, neuroprotective U79_P34 PF03064.11 CDI73803.1 - 3 7.2 33.8 3.5 7.0 23.4 1.0 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Macoilin PF09726.4 CDI73805.1 - 0.003 15.9 24.3 0.0042 15.4 16.8 1.2 1 0 0 1 1 1 1 Transmembrane protein Neur_chan_memb PF02932.11 CDI73805.1 - 0.02 14.7 14.5 0.036 13.9 10.1 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region N6_N4_Mtase PF01555.13 CDI73805.1 - 0.034 13.6 0.0 0.094 12.1 0.0 1.8 1 1 0 1 1 1 0 DNA methylase DUF418 PF04235.7 CDI73805.1 - 0.083 12.5 0.9 0.86 9.2 0.1 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF418) TFIIA PF03153.8 CDI73805.1 - 0.086 12.7 49.6 0.13 12.0 34.4 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4401 PF14351.1 CDI73805.1 - 0.097 11.6 7.1 0.019 13.9 1.7 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4401) DUF2413 PF10310.4 CDI73805.1 - 0.17 10.6 30.4 0.016 14.0 6.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2413) DUF3899 PF13038.1 CDI73805.1 - 0.2 11.8 8.4 3.3 7.9 0.5 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF3899) Utp14 PF04615.8 CDI73805.1 - 0.2 9.7 27.9 0.32 9.1 19.3 1.3 1 0 0 1 1 1 0 Utp14 protein DUF1345 PF07077.6 CDI73805.1 - 0.61 9.5 7.5 0.49 9.8 0.1 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF1345) DUF966 PF06136.8 CDI73805.1 - 0.76 9.1 25.6 1 8.7 17.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Plant_vir_prot PF01307.12 CDI73805.1 - 2.1 8.1 13.0 0.35 10.6 0.5 3.7 2 2 2 4 4 4 0 Plant viral movement protein Cytochrom_B_N PF00033.14 CDI73805.1 - 2.2 7.5 4.5 4.7 6.5 0.1 2.2 2 0 0 2 2 2 0 Cytochrome b(N-terminal)/b6/petB PLRV_ORF5 PF01690.12 CDI73805.1 - 2.6 7.0 20.9 3.6 6.6 14.5 1.2 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein DUF819 PF05684.7 CDI73805.1 - 2.8 6.6 9.0 3.3 6.4 0.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF819) TAF1D PF15333.1 CDI73805.1 - 3.2 7.4 18.3 2.5 7.8 4.3 2.2 2 0 0 2 2 2 0 TATA box-binding protein-associated factor 1D RAP1 PF07218.6 CDI73805.1 - 3.2 5.7 5.3 3.9 5.4 3.7 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) PalH PF08733.5 CDI73805.1 - 4 6.1 8.1 1.3 7.7 1.3 2.2 2 0 0 2 2 2 0 PalH/RIM21 PIG-U PF06728.8 CDI73805.1 - 4.1 6.1 10.6 52 2.5 6.9 2.3 1 1 0 1 1 1 0 GPI transamidase subunit PIG-U SR-25 PF10500.4 CDI73805.1 - 5.6 6.3 41.8 0.085 12.3 13.4 2.3 1 1 1 2 2 2 0 Nuclear RNA-splicing-associated protein SprA-related PF12118.3 CDI73805.1 - 5.9 6.1 65.8 0.44 9.8 14.5 2.4 2 0 0 2 2 2 0 SprA-related family TMEM164 PF14808.1 CDI73805.1 - 9 5.4 8.2 0.79 8.8 0.5 2.1 2 0 0 2 2 2 0 TMEM164 family p25-alpha PF05517.7 CDI73807.1 - 1.7e-38 132.2 2.2 1.9e-38 132.1 1.5 1.0 1 0 0 1 1 1 1 p25-alpha SET PF00856.23 CDI73808.1 - 4e-11 43.4 0.3 4.6e-09 36.7 0.4 2.4 2 1 0 2 2 2 2 SET domain DUF1645 PF07816.6 CDI73808.1 - 0.0052 17.2 2.8 0.012 16.1 2.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1645) Med15 PF09606.5 CDI73809.1 - 1.5e-05 23.4 56.9 1.5e-05 23.4 39.4 5.1 2 1 1 3 3 3 1 ARC105 or Med15 subunit of Mediator complex non-fungal CPSF73-100_C PF11718.3 CDI73809.1 - 3.2e-05 23.4 0.9 3.2e-05 23.4 0.6 7.2 4 4 4 8 8 8 2 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Shadoo PF14999.1 CDI73810.1 - 0.047 13.5 0.2 0.047 13.5 0.2 8.4 6 2 1 7 7 7 0 Shadow of prion protein, neuroprotective CAF-1_p150 PF11600.3 CDI73810.1 - 0.082 12.2 65.3 0.013 14.9 10.4 4.3 4 0 0 4 4 4 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal PAT1 PF09770.4 CDI73811.1 - 0.0015 16.8 19.2 0.0015 16.8 13.3 2.2 2 0 0 2 2 2 1 Topoisomerase II-associated protein PAT1 DUF572 PF04502.8 CDI73811.1 - 0.0063 15.7 23.8 0.08 12.1 9.0 2.1 2 0 0 2 2 2 2 Family of unknown function (DUF572) Ycf1 PF05758.7 CDI73811.1 - 5.2 4.6 21.8 0.028 12.1 3.2 2.1 2 0 0 2 2 2 0 Ycf1 Ribosomal_60s PF00428.14 CDI73813.1 - 0.86 10.0 5.5 1.2 9.5 3.8 1.3 1 0 0 1 1 1 0 60s Acidic ribosomal protein CDC45 PF02724.9 CDI73813.1 - 7.9 4.3 29.1 8.7 4.2 20.2 1.0 1 0 0 1 1 1 0 CDC45-like protein Erv26 PF04148.8 CDI73814.1 - 0.54 9.5 0.2 4.2 6.6 0.2 2.6 1 0 0 1 1 1 0 Transmembrane adaptor Erv26 DUF2434 PF10361.4 CDI73814.1 - 2.8 6.9 1.6 3.8 6.4 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2434) DUF3458 PF11940.3 CDI73815.1 - 6.9e-105 350.8 0.0 9.6e-105 350.4 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3458) Peptidase_M1 PF01433.15 CDI73815.1 - 9.4e-57 192.8 0.0 1.3e-56 192.4 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M1 Peptidase_MA_2 PF13485.1 CDI73815.1 - 1.3e-14 54.3 0.0 3.7e-14 52.8 0.0 1.7 1 0 0 1 1 1 1 Peptidase MA superfamily Peptidase_M61 PF05299.7 CDI73815.1 - 0.071 13.0 2.3 0.57 10.1 1.6 2.3 1 1 0 1 1 1 0 M61 glycyl aminopeptidase Ank_5 PF13857.1 CDI73816.1 - 0.038 14.2 0.0 0.17 12.1 0.0 2.1 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Nol1_Nop2_Fmu PF01189.12 CDI73817.1 - 1.1e-24 87.2 0.0 1.4e-15 57.3 0.0 3.3 3 0 0 3 3 3 3 NOL1/NOP2/sun family SNF2_N PF00176.18 CDI73818.1 - 2.4e-43 148.0 0.1 4.4e-43 147.1 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 CDI73818.1 - 6.6e-13 48.3 0.1 1.4e-11 44.1 0.0 2.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_14 PF13173.1 CDI73818.1 - 0.002 18.0 0.0 0.007 16.2 0.0 1.9 1 0 0 1 1 1 1 AAA domain PHD PF00628.24 CDI73818.1 - 0.0036 16.9 7.8 0.0036 16.9 5.4 4.3 4 1 0 4 4 4 1 PHD-finger DEAD PF00270.24 CDI73818.1 - 0.0076 15.7 0.0 0.021 14.3 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 CDI73818.1 - 0.011 15.5 0.0 0.033 14.0 0.0 1.8 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit SET PF00856.23 CDI73820.1 - 1.9e-11 44.5 0.6 9.7e-10 38.9 0.0 3.3 3 0 0 3 3 3 1 SET domain RapA_C PF12137.3 CDI73820.1 - 0.016 14.0 7.3 0.027 13.3 5.0 1.3 1 0 0 1 1 1 0 RNA polymerase recycling family C-terminal IncA PF04156.9 CDI73820.1 - 5.2 6.6 11.2 4.4 6.8 5.4 2.5 2 0 0 2 2 2 0 IncA protein Arm PF00514.18 CDI73821.1 - 1.4e-09 37.3 3.8 0.032 14.0 0.0 5.4 6 0 0 6 6 6 3 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 CDI73821.1 - 3.6e-08 33.5 0.9 0.0002 21.5 0.0 4.2 2 2 2 4 4 4 2 HEAT repeats V-ATPase_H_C PF11698.3 CDI73821.1 - 3.4e-05 23.7 0.0 0.00015 21.6 0.0 2.0 2 0 0 2 2 2 1 V-ATPase subunit H HEAT PF02985.17 CDI73821.1 - 0.0057 16.6 7.9 10 6.5 0.0 5.7 7 0 0 7 7 7 2 HEAT repeat SPO22 PF08631.5 CDI73821.1 - 0.01 14.9 0.0 0.59 9.1 0.0 2.3 2 0 0 2 2 2 0 Meiosis protein SPO22/ZIP4 like HEAT_EZ PF13513.1 CDI73821.1 - 0.085 13.3 2.6 3.3 8.3 0.0 4.4 6 0 0 6 6 6 0 HEAT-like repeat Tim17 PF02466.14 CDI73823.1 - 2.2e-30 105.2 4.1 3.7e-30 104.5 2.8 1.3 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family UPF0060 PF02694.10 CDI73823.1 - 0.086 12.8 0.8 0.12 12.3 0.1 1.6 2 0 0 2 2 2 0 Uncharacterised BCR, YnfA/UPF0060 family DUF1510 PF07423.6 CDI73827.1 - 0.0037 16.6 21.9 0.004 16.5 15.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) CKAP2_C PF15297.1 CDI73827.1 - 0.083 11.6 22.3 0.11 11.2 15.5 1.2 1 0 0 1 1 1 0 Cytoskeleton-associated protein 2 C-terminus Mem_trans PF03547.13 CDI73827.1 - 0.68 8.1 16.2 0.8 7.9 11.2 1.1 1 0 0 1 1 1 0 Membrane transport protein SAPS PF04499.10 CDI73827.1 - 0.73 8.3 26.9 0.89 8.1 18.6 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Ycf1 PF05758.7 CDI73827.1 - 0.79 7.3 25.4 0.86 7.2 17.6 1.0 1 0 0 1 1 1 0 Ycf1 NPR3 PF03666.8 CDI73827.1 - 1.3 7.5 26.3 1.4 7.3 18.2 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Herpes_DNAp_acc PF04929.7 CDI73827.1 - 6.6 5.5 26.2 7.5 5.4 18.2 1.0 1 0 0 1 1 1 0 Herpes DNA replication accessory factor DUF4045 PF13254.1 CDI73827.1 - 9.5 5.3 27.5 11 5.1 19.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) AAA PF00004.24 CDI73828.1 - 0.025 14.7 0.9 0.56 10.4 0.0 3.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 CDI73828.1 - 0.037 13.7 0.0 0.13 12.0 0.0 1.9 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 CDI73828.1 - 0.26 12.1 0.0 0.53 11.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain SR-25 PF10500.4 CDI73830.1 - 0.022 14.2 12.1 0.024 14.1 8.4 1.0 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF1764 PF08576.5 CDI73830.1 - 0.31 11.8 18.6 0.33 11.7 12.9 1.1 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) DDRGK PF09756.4 CDI73830.1 - 0.42 9.9 22.7 0.46 9.8 15.7 1.1 1 0 0 1 1 1 0 DDRGK domain Peptidase_U57 PF05582.7 CDI73830.1 - 0.61 8.9 14.0 0.67 8.8 9.7 1.0 1 0 0 1 1 1 0 YabG peptidase U57 CD20 PF04103.10 CDI73830.1 - 0.62 9.9 4.5 0.81 9.6 3.1 1.3 1 0 0 1 1 1 0 CD20-like family DUF3292 PF11696.3 CDI73830.1 - 0.62 7.8 7.6 0.73 7.6 5.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) F-protein PF00469.15 CDI73830.1 - 0.73 9.1 17.8 0.81 9.0 12.3 1.0 1 0 0 1 1 1 0 Negative factor, (F-Protein) or Nef DUF2052 PF09747.4 CDI73830.1 - 0.8 9.6 21.8 0.93 9.3 15.1 1.0 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) DUF1510 PF07423.6 CDI73830.1 - 0.9 8.8 17.3 0.97 8.7 12.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DUF4175 PF13779.1 CDI73830.1 - 0.92 7.1 44.8 0.9 7.1 31.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) DDHD PF02862.12 CDI73830.1 - 0.97 9.1 18.1 1.1 9.0 12.6 1.0 1 0 0 1 1 1 0 DDHD domain FAM60A PF15396.1 CDI73830.1 - 0.98 9.1 12.6 1.1 8.9 8.7 1.0 1 0 0 1 1 1 0 Protein Family FAM60A MRI PF15325.1 CDI73830.1 - 1.1 10.3 8.6 1.2 10.1 5.9 1.1 1 0 0 1 1 1 0 Modulator of retrovirus infection AIF_C PF14721.1 CDI73830.1 - 1.2 9.3 14.8 1.3 9.2 10.2 1.1 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term FimP PF09766.4 CDI73830.1 - 1.4 7.9 30.3 1.7 7.6 21.0 1.2 1 0 0 1 1 1 0 Fms-interacting protein FYDLN_acid PF09538.5 CDI73830.1 - 1.5 9.4 9.5 1.8 9.2 6.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) DUF3408 PF11888.3 CDI73830.1 - 1.5 8.7 15.9 1.8 8.4 11.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) Bud13 PF09736.4 CDI73830.1 - 1.6 8.9 21.7 1.8 8.8 15.0 1.1 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex FLO_LFY PF01698.11 CDI73830.1 - 1.7 7.3 17.6 2 7.2 12.2 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein PEX11 PF05648.9 CDI73830.1 - 1.8 7.7 9.8 2.2 7.5 6.8 1.1 1 0 0 1 1 1 0 Peroxisomal biogenesis factor 11 (PEX11) FAM176 PF14851.1 CDI73830.1 - 2 8.0 9.9 2.2 7.9 6.9 1.2 1 0 0 1 1 1 0 FAM176 family Neugrin PF06413.6 CDI73830.1 - 2 8.1 14.9 2.4 7.9 10.3 1.0 1 0 0 1 1 1 0 Neugrin Cyclin_C PF02984.14 CDI73830.1 - 2.3 8.1 8.4 2.9 7.8 5.8 1.1 1 0 0 1 1 1 0 Cyclin, C-terminal domain DUF4045 PF13254.1 CDI73830.1 - 2.5 7.2 14.5 2.7 7.1 10.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) DUF3381 PF11861.3 CDI73830.1 - 2.6 7.5 16.7 3 7.3 11.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) Paf1 PF03985.8 CDI73830.1 - 3.1 6.4 21.8 3.2 6.3 15.1 1.0 1 0 0 1 1 1 0 Paf1 Gti1_Pac2 PF09729.4 CDI73830.1 - 3.2 7.6 12.1 3.4 7.5 8.4 1.1 1 0 0 1 1 1 0 Gti1/Pac2 family PPP4R2 PF09184.6 CDI73830.1 - 3.3 7.1 16.0 3.6 7.0 11.1 1.0 1 0 0 1 1 1 0 PPP4R2 Tim54 PF11711.3 CDI73830.1 - 3.6 6.0 13.0 3.8 6.0 9.0 1.0 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Dala_Dala_lig_N PF01820.16 CDI73830.1 - 3.7 7.8 9.0 4.6 7.5 6.2 1.3 1 0 0 1 1 1 0 D-ala D-ala ligase N-terminus Med19 PF10278.4 CDI73830.1 - 3.8 7.1 12.8 4 7.0 8.9 1.1 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 PH_4 PF15404.1 CDI73830.1 - 4.1 6.8 12.7 5.3 6.5 8.8 1.4 1 0 0 1 1 1 0 Pleckstrin homology domain Baculo_PP31 PF05311.6 CDI73830.1 - 4.3 6.5 18.7 4.5 6.4 13.0 1.1 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) Sox_N PF12444.3 CDI73830.1 - 4.4 8.4 11.2 5.8 8.1 7.7 1.2 1 0 0 1 1 1 0 Sox developmental protein N terminal ARF7EP_C PF14949.1 CDI73830.1 - 4.4 7.7 14.0 4.9 7.6 9.7 1.2 1 0 0 1 1 1 0 ARF7 effector protein C-terminus TCP PF03634.8 CDI73830.1 - 4.6 7.6 19.5 5.6 7.3 13.5 1.1 1 0 0 1 1 1 0 TCP family transcription factor DUF3449 PF11931.3 CDI73830.1 - 4.6 6.6 17.7 5 6.5 12.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3449) Spore_coat_CotO PF14153.1 CDI73830.1 - 4.6 6.6 26.6 5 6.5 18.5 1.0 1 0 0 1 1 1 0 Spore coat protein CotO Serinc PF03348.10 CDI73830.1 - 5 5.7 18.7 5.1 5.6 13.0 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) CPSF100_C PF13299.1 CDI73830.1 - 5.3 7.2 15.0 5.6 7.1 10.4 1.1 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Pal1 PF08316.6 CDI73830.1 - 5.7 7.4 9.6 6.4 7.2 6.7 1.1 1 0 0 1 1 1 0 Pal1 cell morphology protein Herpes_env PF01673.13 CDI73830.1 - 5.7 5.3 12.0 5.8 5.3 8.3 1.0 1 0 0 1 1 1 0 Herpesvirus putative major envelope glycoprotein Ctr PF04145.10 CDI73830.1 - 6 6.9 11.3 7.8 6.5 7.9 1.4 1 0 0 1 1 1 0 Ctr copper transporter family SeqA PF03925.8 CDI73830.1 - 6 6.5 14.9 6.4 6.4 10.3 1.1 1 0 0 1 1 1 0 SeqA protein Late_protein_L2 PF00513.13 CDI73830.1 - 6 5.6 11.0 6.3 5.5 7.6 1.0 1 0 0 1 1 1 0 Late Protein L2 Cellulose_synt PF03552.9 CDI73830.1 - 6.1 5.0 8.6 5.7 5.1 6.0 1.0 1 0 0 1 1 1 0 Cellulose synthase RNA_pol_Rpb1_5 PF04998.12 CDI73830.1 - 6.3 5.9 9.8 6.8 5.8 6.8 1.0 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 PRTP PF01366.13 CDI73830.1 - 6.3 4.6 14.3 6 4.7 9.9 1.0 1 0 0 1 1 1 0 Herpesvirus processing and transport protein DUF3373 PF11853.3 CDI73830.1 - 6.4 5.1 15.5 7 5.0 10.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) BORG_CEP PF14957.1 CDI73830.1 - 6.7 7.6 14.0 7.4 7.5 9.7 1.1 1 0 0 1 1 1 0 Cdc42 effector HD-ZIP_N PF04618.7 CDI73830.1 - 7.3 7.1 10.0 9.6 6.7 6.9 1.3 1 0 0 1 1 1 0 HD-ZIP protein N terminus TFIIA PF03153.8 CDI73830.1 - 7.8 6.2 34.2 8.7 6.1 23.7 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Peptidase_S49_N PF08496.5 CDI73830.1 - 7.8 6.2 15.9 9.4 6.0 11.0 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal FAM91_C PF14648.1 CDI73830.1 - 8.6 5.0 8.1 8.9 5.0 5.6 1.0 1 0 0 1 1 1 0 FAM91 C-terminus SprA-related PF12118.3 CDI73830.1 - 9 5.5 42.3 11 5.2 29.3 1.1 1 0 0 1 1 1 0 SprA-related family PIH1 PF08190.7 CDI73830.1 - 9.1 5.6 23.6 8.7 5.6 16.4 1.0 1 0 0 1 1 1 0 pre-RNA processing PIH1/Nop17 DUF702 PF05142.7 CDI73830.1 - 9.2 6.4 16.0 13 5.9 11.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF702) NARP1 PF12569.3 CDI73830.1 - 9.5 4.8 21.5 11 4.6 14.9 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Rtf2 PF04641.7 CDI73830.1 - 9.6 5.3 17.5 9.7 5.2 12.1 1.0 1 0 0 1 1 1 0 Rtf2 RING-finger Spc7_N PF15402.1 CDI73830.1 - 9.6 4.0 22.3 11 3.8 15.5 1.0 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 Hid1 PF12722.2 CDI73830.1 - 9.7 3.7 21.0 10 3.6 14.6 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Band_3_cyto PF07565.8 CDI73830.1 - 9.7 5.6 21.7 10 5.5 15.1 1.0 1 0 0 1 1 1 0 Band 3 cytoplasmic domain GPCR_chapero_1 PF11904.3 CDI73830.1 - 9.8 5.2 14.3 9.2 5.2 9.9 1.0 1 0 0 1 1 1 0 GPCR-chaperone HGTP_anticodon2 PF12745.2 CDI73830.1 - 9.8 5.2 15.4 10 5.1 10.7 1.1 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs IncA PF04156.9 CDI73831.1 - 0.0002 21.0 4.3 0.00024 20.7 3.0 1.1 1 0 0 1 1 1 1 IncA protein Claudin_2 PF13903.1 CDI73831.1 - 0.0023 17.6 6.2 0.0025 17.5 4.3 1.1 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction Peptidase_M56 PF05569.6 CDI73831.1 - 0.39 9.6 7.4 0.43 9.5 5.1 1.0 1 0 0 1 1 1 0 BlaR1 peptidase M56 DUF726 PF05277.7 CDI73831.1 - 0.52 9.1 10.8 0.64 8.8 7.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF726) Med15 PF09606.5 CDI73831.1 - 0.77 7.8 24.1 0.82 7.7 16.7 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF3451 PF11933.3 CDI73831.1 - 0.79 9.4 7.0 1 9.1 4.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3451) Mucin PF01456.12 CDI73831.1 - 1.7 8.4 29.2 2.1 8.1 20.3 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein DUF2232 PF09991.4 CDI73831.1 - 2.4 7.0 5.2 2.9 6.7 3.6 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) DUF4349 PF14257.1 CDI73831.1 - 6 6.0 24.7 8 5.6 17.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) BSP_II PF05432.6 CDI73831.1 - 8.5 5.5 8.3 9.9 5.3 5.7 1.1 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) MSP1_C PF07462.6 CDI73831.1 - 8.8 4.5 20.0 9.8 4.4 13.9 1.1 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus PAT1 PF09770.4 CDI73832.1 - 0.0087 14.3 66.2 0.011 14.0 45.9 1.0 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 SDA1 PF05285.7 CDI73832.1 - 0.0098 15.2 48.0 0.011 15.0 33.3 1.1 1 0 0 1 1 1 1 SDA1 Daxx PF03344.10 CDI73832.1 - 0.098 11.1 54.9 0.11 10.9 38.0 1.0 1 0 0 1 1 1 0 Daxx Family DUF668 PF05003.7 CDI73832.1 - 1.3 9.3 17.8 8.2 6.7 7.6 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF668) Macoilin PF09726.4 CDI73832.1 - 1.5 6.9 50.6 1.9 6.6 35.0 1.0 1 0 0 1 1 1 0 Transmembrane protein Hydantoinase_A PF01968.13 CDI73832.1 - 3 6.8 6.5 4.5 6.2 4.5 1.4 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase Trypan_PARP PF05887.6 CDI73832.1 - 4.3 7.1 20.2 6.3 6.6 14.0 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) YpjP PF14005.1 CDI73832.1 - 9.2 6.0 18.0 26 4.5 10.1 2.5 1 1 1 2 2 2 0 YpjP-like protein Gag_spuma PF03276.9 CDI73833.1 - 0.056 11.7 38.5 0.058 11.7 26.7 1.0 1 0 0 1 1 1 0 Spumavirus gag protein SpoIIP PF07454.6 CDI73833.1 - 0.19 10.8 20.5 0.22 10.6 14.2 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Band_3_cyto PF07565.8 CDI73833.1 - 0.65 9.4 18.4 0.77 9.2 12.8 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain DUF2360 PF10152.4 CDI73833.1 - 0.93 9.7 17.1 1.1 9.4 11.9 1.1 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) Baculo_PP31 PF05311.6 CDI73833.1 - 1.1 8.4 22.5 1.4 8.0 15.6 1.3 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) PAT1 PF09770.4 CDI73833.1 - 1.2 7.3 38.0 1.3 7.1 26.3 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Vfa1 PF08432.5 CDI73833.1 - 1.3 8.9 33.2 1.6 8.7 23.0 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 eIF-3_zeta PF05091.7 CDI73833.1 - 1.3 7.5 28.4 1.4 7.4 19.7 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF966 PF06136.8 CDI73833.1 - 1.5 8.2 22.6 1.5 8.1 15.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF966) SprA-related PF12118.3 CDI73833.1 - 1.5 8.1 44.6 1.7 7.8 30.9 1.2 1 0 0 1 1 1 0 SprA-related family DUF2072 PF09845.4 CDI73833.1 - 1.7 8.5 15.2 2.1 8.2 10.6 1.3 1 0 0 1 1 1 0 Zn-ribbon containing protein (DUF2072) RR_TM4-6 PF06459.7 CDI73833.1 - 1.8 8.3 29.4 2.3 8.0 20.4 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Rtf2 PF04641.7 CDI73833.1 - 2 7.5 27.5 2.2 7.4 19.1 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger Raftlin PF15250.1 CDI73833.1 - 2.1 6.7 21.2 2.3 6.6 14.7 1.0 1 0 0 1 1 1 0 Raftlin LicD PF04991.8 CDI73833.1 - 2.1 8.3 10.1 2.3 8.2 7.0 1.1 1 0 0 1 1 1 0 LicD family Zip PF02535.17 CDI73833.1 - 2.7 6.8 11.6 3.1 6.7 8.1 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter Peptidase_U57 PF05582.7 CDI73833.1 - 2.9 6.7 17.8 3.2 6.6 12.4 1.2 1 0 0 1 1 1 0 YabG peptidase U57 Spore_coat_CotO PF14153.1 CDI73833.1 - 3.1 7.2 36.9 3.2 7.1 25.6 1.1 1 0 0 1 1 1 0 Spore coat protein CotO DDHD PF02862.12 CDI73833.1 - 3.2 7.4 23.9 3.7 7.2 16.6 1.1 1 0 0 1 1 1 0 DDHD domain AUX_IAA PF02309.11 CDI73833.1 - 3.6 7.2 21.8 4.4 6.9 15.1 1.2 1 0 0 1 1 1 0 AUX/IAA family DUF3807 PF12720.2 CDI73833.1 - 3.7 7.6 32.6 4.4 7.4 22.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) CPSF100_C PF13299.1 CDI73833.1 - 4.1 7.5 19.5 5.4 7.1 13.5 1.4 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal TFIIA PF03153.8 CDI73833.1 - 4.5 7.0 36.0 5.3 6.8 25.0 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit FLO_LFY PF01698.11 CDI73833.1 - 4.7 5.9 26.3 5.1 5.8 18.2 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein DUF4557 PF15101.1 CDI73833.1 - 4.7 6.9 31.6 6.5 6.5 21.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) Hid1 PF12722.2 CDI73833.1 - 5.2 4.6 26.0 5.1 4.6 18.1 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Pox_Ag35 PF03286.9 CDI73833.1 - 5.4 6.4 24.6 6.4 6.2 17.0 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein F-protein PF00469.15 CDI73833.1 - 5.5 6.3 20.3 6.2 6.1 14.1 1.1 1 0 0 1 1 1 0 Negative factor, (F-Protein) or Nef BORG_CEP PF14957.1 CDI73833.1 - 5.7 7.8 17.5 7.5 7.4 12.1 1.2 1 0 0 1 1 1 0 Cdc42 effector Paf1 PF03985.8 CDI73833.1 - 5.9 5.5 31.2 6.5 5.3 21.6 1.2 1 0 0 1 1 1 0 Paf1 FNIP_N PF14636.1 CDI73833.1 - 6.3 7.2 20.3 7.5 7.0 14.1 1.3 1 0 0 1 1 1 0 Folliculin-interacting protein N-terminus Hom_end_hint PF05203.11 CDI73833.1 - 6.3 6.4 16.6 7.8 6.1 11.5 1.3 1 0 0 1 1 1 0 Hom_end-associated Hint DUF4045 PF13254.1 CDI73833.1 - 7.1 5.7 24.5 8.1 5.6 17.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) CobT PF06213.7 CDI73833.1 - 7.7 5.5 22.1 8.6 5.3 15.3 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT MDFI PF15316.1 CDI73833.1 - 8 6.4 12.2 9.9 6.1 8.5 1.2 1 0 0 1 1 1 0 MyoD family inhibitor POP1 PF06978.6 CDI73833.1 - 8.2 6.0 22.4 11 5.6 15.5 1.3 1 0 0 1 1 1 0 Ribonucleases P/MRP protein subunit POP1 DHHW PF14286.1 CDI73833.1 - 8.3 5.6 19.9 8.9 5.5 13.8 1.1 1 0 0 1 1 1 0 DHHW protein DDRGK PF09756.4 CDI73833.1 - 8.9 5.6 40.4 11 5.3 28.0 1.3 1 0 0 1 1 1 0 DDRGK domain DUF3513 PF12026.3 CDI73833.1 - 9.3 5.7 27.2 12 5.3 18.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3513) GAGA_bind PF06217.7 CDI73833.1 - 9.8 6.0 26.9 11 5.8 18.6 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family SR-25 PF10500.4 CDI73834.1 - 5.4 6.4 22.1 7.9 5.8 15.3 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein AIF_C PF14721.1 CDI73834.1 - 7 6.9 16.9 7.8 6.7 11.7 1.1 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Pal1 PF08316.6 CDI73834.1 - 9.1 6.7 13.0 9.3 6.7 9.0 1.0 1 0 0 1 1 1 0 Pal1 cell morphology protein Rgp1 PF08737.5 CDI73836.1 - 0.02 13.9 5.3 0.033 13.2 3.7 1.3 1 0 0 1 1 1 0 Rgp1 FimP PF09766.4 CDI73836.1 - 0.066 12.2 20.6 0.015 14.3 9.1 2.0 2 0 0 2 2 2 0 Fms-interacting protein OATP PF03137.15 CDI73836.1 - 0.37 8.7 1.3 0.42 8.5 0.9 1.2 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family DUF3373 PF11853.3 CDI73836.1 - 0.42 9.0 8.6 0.43 9.0 5.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) Presenilin PF01080.12 CDI73836.1 - 0.45 9.2 3.9 0.47 9.2 2.7 1.2 1 0 0 1 1 1 0 Presenilin PAD_M PF08527.5 CDI73836.1 - 0.49 9.7 6.1 0.65 9.3 4.3 1.3 1 0 0 1 1 1 0 Protein-arginine deiminase (PAD) middle domain DUF4446 PF14584.1 CDI73836.1 - 1.5 8.5 12.0 0.74 9.6 3.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) PMSI1 PF15322.1 CDI73836.1 - 2.1 7.3 11.4 0.13 11.3 4.4 1.5 2 0 0 2 2 2 0 Protein missing in infertile sperm 1, putative DUF4228 PF14009.1 CDI73836.1 - 2.6 8.1 13.2 0.82 9.7 4.5 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4228) R_equi_Vir PF05526.6 CDI73836.1 - 3.6 7.1 8.5 0.51 9.9 3.1 1.6 2 0 0 2 2 2 0 Rhodococcus equi virulence-associated protein MARCKS PF02063.12 CDI73836.1 - 4.6 7.0 11.7 6.3 6.5 8.1 1.1 1 0 0 1 1 1 0 MARCKS family DUF775 PF05603.7 CDI73836.1 - 5.4 6.4 13.2 0.28 10.6 5.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF775) Androgen_recep PF02166.11 CDI73837.1 - 0.029 13.2 3.6 0.028 13.2 2.5 1.0 1 0 0 1 1 1 0 Androgen receptor Lipoprotein_19 PF13617.1 CDI73837.1 - 0.12 12.0 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 YnbE-like lipoprotein FimP PF09766.4 CDI73837.1 - 0.3 10.1 7.4 0.27 10.2 5.1 1.1 1 0 0 1 1 1 0 Fms-interacting protein FCP1_C PF09309.5 CDI73837.1 - 0.37 10.0 5.9 0.4 9.9 4.1 1.0 1 0 0 1 1 1 0 FCP1, C-terminal Spt20 PF12090.3 CDI73837.1 - 0.5 9.6 4.3 0.49 9.7 3.0 1.1 1 0 0 1 1 1 0 Spt20 family ERF PF04404.7 CDI73837.1 - 0.92 9.0 8.7 1.1 8.7 6.0 1.2 1 0 0 1 1 1 0 ERF superfamily DUF3682 PF12446.3 CDI73837.1 - 1.8 8.8 17.1 2.2 8.5 11.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) TSA PF03249.8 CDI73837.1 - 1.9 6.9 10.6 2 6.8 7.4 1.0 1 0 0 1 1 1 0 Type specific antigen DUF4175 PF13779.1 CDI73837.1 - 2 5.9 13.1 1.9 6.0 9.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Folate_carrier PF01770.13 CDI73838.1 - 0.87 8.0 7.5 3.3 6.1 0.3 2.6 2 0 0 2 2 2 0 Reduced folate carrier BAF1_ABF1 PF04684.8 CDI73839.1 - 0.023 13.5 8.9 0.03 13.1 6.2 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Mitofilin PF09731.4 CDI73839.1 - 6.1 5.3 18.8 6.8 5.2 13.0 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein NAP PF00956.13 CDI73842.1 - 6e-14 51.7 4.0 9.3e-08 31.4 1.2 3.9 2 1 2 4 4 3 2 Nucleosome assembly protein (NAP) Cwf_Cwc_15 PF04889.7 CDI73842.1 - 0.0078 15.9 3.8 0.0078 15.9 2.6 2.1 2 0 0 2 2 2 1 Cwf15/Cwc15 cell cycle control protein Nop14 PF04147.7 CDI73842.1 - 0.02 12.8 13.6 0.022 12.7 9.4 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.7 CDI73842.1 - 0.028 13.7 17.2 0.048 12.9 12.0 1.4 1 0 0 1 1 1 0 SDA1 Oligomerisation PF02410.10 CDI73842.1 - 0.047 13.7 1.8 0.093 12.7 1.3 1.4 1 0 0 1 1 1 0 Oligomerisation domain Apt1 PF10351.4 CDI73842.1 - 0.056 12.3 4.8 0.09 11.6 3.4 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain FAD-SLDH PF12318.3 CDI73842.1 - 0.13 11.9 9.6 0.45 10.1 5.3 2.4 3 0 0 3 3 3 0 Membrane bound FAD containing D-sorbitol dehydrogenase Med15 PF09606.5 CDI73842.1 - 0.77 7.8 30.1 1 7.5 20.8 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal AAA_33 PF13671.1 CDI73842.1 - 0.82 9.5 5.5 1.6 8.6 3.8 1.4 1 0 0 1 1 1 0 AAA domain Kinetocho_Slk19 PF12709.2 CDI73842.1 - 1.2 9.2 18.9 0.65 10.1 0.4 2.6 2 0 0 2 2 2 0 Central kinetochore-associated OmpH PF03938.9 CDI73842.1 - 3.1 7.7 25.8 0.52 10.2 12.2 2.2 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) DUF904 PF06005.7 CDI73842.1 - 4.8 7.5 20.1 7.6 6.9 9.9 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF904) Nucleoplasmin PF03066.10 CDI73842.1 - 5 6.6 14.1 0.8 9.2 5.4 2.3 2 0 0 2 2 2 0 Nucleoplasmin DUF1840 PF08895.6 CDI73842.1 - 7.5 6.6 12.8 5 7.1 4.5 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF1840) Sigma70_ner PF04546.8 CDI73842.1 - 7.6 6.0 19.7 0.21 11.1 8.9 1.8 2 1 0 2 2 2 0 Sigma-70, non-essential region Hid1 PF12722.2 CDI73842.1 - 9.1 3.8 9.5 11 3.5 6.6 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein AIF_C PF14721.1 CDI73843.1 - 0.007 16.6 10.4 0.011 16.0 7.2 1.2 1 0 0 1 1 1 1 Apoptosis-inducing factor, mitochondrion-associated, C-term DDHD PF02862.12 CDI73843.1 - 0.013 15.3 14.1 0.016 15.0 9.7 1.1 1 0 0 1 1 1 0 DDHD domain RR_TM4-6 PF06459.7 CDI73843.1 - 0.015 15.2 15.2 0.019 14.9 10.5 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Baculo_PP31 PF05311.6 CDI73843.1 - 0.017 14.4 13.3 0.019 14.2 9.2 1.1 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) Tim54 PF11711.3 CDI73843.1 - 0.023 13.3 13.9 0.031 12.8 9.6 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 OmpH PF03938.9 CDI73843.1 - 0.035 14.0 44.5 0.042 13.7 30.9 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF2828 PF11443.3 CDI73843.1 - 0.16 10.1 11.8 0.18 9.9 8.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) FLO_LFY PF01698.11 CDI73843.1 - 0.18 10.6 15.4 0.22 10.3 10.7 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein Ycf1 PF05758.7 CDI73843.1 - 0.23 9.1 17.8 0.26 8.9 12.3 1.0 1 0 0 1 1 1 0 Ycf1 CobT PF06213.7 CDI73843.1 - 0.32 10.1 14.1 0.4 9.7 9.8 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Gag_spuma PF03276.9 CDI73843.1 - 0.34 9.1 38.1 0.56 8.4 26.4 1.3 1 0 0 1 1 1 0 Spumavirus gag protein AUX_IAA PF02309.11 CDI73843.1 - 0.35 10.5 14.1 0.45 10.2 9.8 1.2 1 0 0 1 1 1 0 AUX/IAA family GAGA_bind PF06217.7 CDI73843.1 - 0.35 10.7 16.1 0.42 10.5 11.1 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family AAA_23 PF13476.1 CDI73843.1 - 0.44 10.8 28.2 0.52 10.6 19.5 1.1 1 0 0 1 1 1 0 AAA domain Zip PF02535.17 CDI73843.1 - 0.46 9.4 5.0 0.56 9.1 3.5 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter DUF4045 PF13254.1 CDI73843.1 - 0.54 9.4 16.5 0.67 9.1 11.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Serinc PF03348.10 CDI73843.1 - 0.62 8.7 16.7 0.8 8.3 11.6 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) Band_3_cyto PF07565.8 CDI73843.1 - 0.67 9.4 18.3 0.94 8.9 12.7 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain CPSF100_C PF13299.1 CDI73843.1 - 1.9 8.6 17.9 2.4 8.3 12.4 1.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal OATP PF03137.15 CDI73843.1 - 1.9 6.4 13.1 2.6 6.0 9.1 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Peptidase_S49_N PF08496.5 CDI73843.1 - 2.3 8.0 18.1 3.8 7.3 12.5 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Hid1 PF12722.2 CDI73843.1 - 5.1 4.6 23.8 6.2 4.3 16.5 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Folate_carrier PF01770.13 CDI73843.1 - 5.7 5.3 14.0 7.4 4.9 9.7 1.0 1 0 0 1 1 1 0 Reduced folate carrier DUF3260 PF11658.3 CDI73843.1 - 5.9 4.9 20.1 6.8 4.7 13.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3260) TFIIA PF03153.8 CDI73843.1 - 6.2 6.6 40.6 8.4 6.1 28.1 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit eIF-3_zeta PF05091.7 CDI73843.1 - 7.5 5.0 29.7 9.7 4.6 20.6 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Herpes_DNAp_acc PF04929.7 CDI73843.1 - 8.8 5.1 16.3 11 4.8 11.3 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Band_3_cyto PF07565.8 CDI73844.1 - 0.014 14.9 10.4 0.016 14.7 7.2 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain FAM176 PF14851.1 CDI73844.1 - 0.038 13.6 1.1 0.048 13.3 0.7 1.4 1 0 0 1 1 1 0 FAM176 family TT_ORF1 PF02956.9 CDI73844.1 - 0.042 12.3 6.0 0.045 12.2 4.1 1.1 1 0 0 1 1 1 0 TT viral orf 1 Pex16 PF08610.5 CDI73844.1 - 0.044 12.7 7.1 0.043 12.8 4.9 1.2 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) DUF4045 PF13254.1 CDI73844.1 - 0.052 12.8 9.1 0.061 12.5 6.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) ABC2_membrane_2 PF12679.2 CDI73844.1 - 0.087 11.6 2.1 0.11 11.2 1.4 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein Med15 PF09606.5 CDI73844.1 - 0.11 10.6 48.1 0.18 9.9 33.3 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF940 PF06082.6 CDI73844.1 - 0.15 10.5 8.5 0.2 10.1 5.9 1.3 1 0 0 1 1 1 0 Bacterial putative lipoprotein (DUF940) DUF3449 PF11931.3 CDI73844.1 - 0.21 11.0 10.3 0.33 10.4 7.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3449) AUX_IAA PF02309.11 CDI73844.1 - 0.33 10.6 6.6 0.35 10.5 4.6 1.2 1 0 0 1 1 1 0 AUX/IAA family Hid1 PF12722.2 CDI73844.1 - 0.49 8.0 9.8 0.49 8.0 6.8 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF3984 PF13136.1 CDI73844.1 - 0.6 9.2 10.6 1 8.5 7.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3984) Ycf1 PF05758.7 CDI73844.1 - 0.61 7.7 8.9 0.63 7.6 6.2 1.0 1 0 0 1 1 1 0 Ycf1 DUF966 PF06136.8 CDI73844.1 - 0.78 9.0 11.4 0.95 8.8 7.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Neur_chan_memb PF02932.11 CDI73844.1 - 0.83 9.4 5.9 0.97 9.2 4.1 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region SOBP PF15279.1 CDI73844.1 - 0.83 9.9 11.6 0.99 9.7 8.0 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein FemAB PF02388.11 CDI73844.1 - 0.84 8.2 12.9 0.97 8.0 8.9 1.1 1 0 0 1 1 1 0 FemAB family SID-1_RNA_chan PF13965.1 CDI73844.1 - 1.4 6.9 5.8 1.7 6.6 4.0 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 VID27 PF08553.5 CDI73844.1 - 1.6 6.8 10.3 1.9 6.6 7.1 1.0 1 0 0 1 1 1 0 VID27 cytoplasmic protein Asp-B-Hydro_N PF05279.6 CDI73844.1 - 1.7 8.4 10.4 1.9 8.2 7.2 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Herpes_TAF50 PF03326.8 CDI73844.1 - 2.1 7.1 22.5 2.6 6.8 15.6 1.0 1 0 0 1 1 1 0 Herpesvirus transcription activation factor (transactivator) IER PF05760.7 CDI73844.1 - 3.8 7.3 17.2 4.6 7.0 11.9 1.0 1 0 0 1 1 1 0 Immediate early response protein (IER) Calici_coat_C PF08435.6 CDI73844.1 - 4.3 6.5 14.6 4.3 6.5 10.0 1.2 1 1 0 1 1 1 0 Calicivirus coat protein C-terminal GNT-I PF03071.10 CDI73844.1 - 4.6 5.6 10.2 6.8 5.1 7.1 1.2 1 0 0 1 1 1 0 GNT-I family PAT1 PF09770.4 CDI73844.1 - 4.9 5.2 41.3 6 4.9 28.6 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Hom_end_hint PF05203.11 CDI73844.1 - 5.3 6.7 9.1 9.1 5.9 6.3 1.3 1 0 0 1 1 1 0 Hom_end-associated Hint Mcm10 PF09332.6 CDI73844.1 - 5.5 6.2 15.6 7.2 5.8 10.8 1.2 1 0 0 1 1 1 0 Mcm10 replication factor CPSF100_C PF13299.1 CDI73844.1 - 5.7 7.0 11.8 11 6.2 8.2 1.4 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Paramyxo_ncap PF00973.14 CDI73844.1 - 6.3 5.3 8.4 6.4 5.3 5.9 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Serinc PF03348.10 CDI73844.1 - 6.9 5.2 10.8 9.8 4.7 7.5 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) DUF4175 PF13779.1 CDI73844.1 - 9.7 3.7 38.7 13 3.3 26.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) MOZ_SAS PF01853.13 CDI73846.1 - 7.6e-75 250.2 0.0 1e-74 249.9 0.0 1.1 1 0 0 1 1 1 1 MOZ/SAS family Tudor-knot PF11717.3 CDI73846.1 - 5e-08 32.5 0.0 9.1e-08 31.6 0.0 1.4 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain PP2C PF00481.16 CDI73847.1 - 7.1e-37 127.1 0.0 2.3e-36 125.4 0.0 1.7 2 0 0 2 2 2 1 Protein phosphatase 2C SpoIIE PF07228.7 CDI73847.1 - 0.001 18.8 0.0 0.087 12.5 0.0 2.8 3 0 0 3 3 3 1 Stage II sporulation protein E (SpoIIE) DUF3347 PF11827.3 CDI73847.1 - 0.35 10.8 4.7 0.58 10.1 3.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3347) IncA PF04156.9 CDI73849.1 - 0.00068 19.2 27.4 0.039 13.5 5.3 2.4 2 0 0 2 2 2 2 IncA protein GAS PF13851.1 CDI73849.1 - 0.09 11.9 23.4 0.062 12.4 8.8 2.3 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Cyc-maltodext_C PF10438.4 CDI73849.1 - 0.099 12.7 0.2 0.22 11.5 0.1 1.5 1 0 0 1 1 1 0 Cyclo-malto-dextrinase C-terminal domain Spc7 PF08317.6 CDI73849.1 - 0.22 10.1 20.7 0.16 10.5 8.3 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF3166 PF11365.3 CDI73849.1 - 0.24 11.8 15.7 0.21 12.0 3.4 3.7 2 1 2 4 4 4 0 Protein of unknown function (DUF3166) GNT-I PF03071.10 CDI73849.1 - 0.53 8.7 5.3 0.25 9.8 1.7 1.8 1 1 1 2 2 2 0 GNT-I family Prefoldin PF02996.12 CDI73849.1 - 5.1 6.7 16.8 3.2 7.4 0.8 3.6 2 1 0 3 3 3 0 Prefoldin subunit BLOC1_2 PF10046.4 CDI73849.1 - 9.5 6.4 10.9 2.4 8.3 1.9 3.0 1 1 2 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 E1-E2_ATPase PF00122.15 CDI73850.1 - 2.9e-61 206.4 2.9 5e-61 205.6 2.0 1.4 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 CDI73850.1 - 6.7e-35 120.2 2.8 1.7e-34 118.9 0.0 2.6 2 1 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 CDI73850.1 - 4.6e-30 105.6 0.0 1.8e-29 103.7 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 CDI73850.1 - 4e-19 67.8 0.0 9.9e-19 66.5 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 CDI73850.1 - 1.7e-12 47.9 0.2 8.1e-12 45.6 0.1 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 CDI73850.1 - 5.1e-09 35.9 0.0 1.8e-08 34.2 0.0 1.9 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 CDI73850.1 - 0.0025 17.4 1.0 0.0045 16.6 0.3 1.6 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF1685 PF07939.6 CDI73850.1 - 0.18 11.4 2.9 0.12 12.0 0.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1685) Orbi_VP6 PF01516.11 CDI73850.1 - 0.79 8.7 3.2 1.4 7.9 2.2 1.3 1 0 0 1 1 1 0 Orbivirus helicase VP6 OmpH PF03938.9 CDI73852.1 - 0.33 10.8 0.0 0.33 10.8 0.0 17.7 9 5 3 12 12 12 0 Outer membrane protein (OmpH-like) Med15 PF09606.5 CDI73853.1 - 8.3e-08 30.9 87.5 1e-07 30.6 60.7 1.1 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal PAT1 PF09770.4 CDI73853.1 - 0.11 10.7 66.6 0.14 10.4 46.2 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 RNase_E_G PF10150.4 CDI73853.1 - 0.26 10.4 10.7 0.37 9.9 7.4 1.2 1 0 0 1 1 1 0 Ribonuclease E/G family PsaN PF05479.6 CDI73853.1 - 0.84 9.6 7.4 4.9 7.1 1.3 2.4 2 0 0 2 2 2 0 Photosystem I reaction centre subunit N (PSAN or PSI-N) Herpes_DNAp_acc PF04929.7 CDI73853.1 - 1.2 8.0 10.8 2 7.2 7.5 1.4 1 1 0 1 1 1 0 Herpes DNA replication accessory factor Ribosomal_60s PF00428.14 CDI73853.1 - 1.7 9.1 23.4 2.3 8.6 7.7 2.8 2 0 0 2 2 2 0 60s Acidic ribosomal protein PLRV_ORF5 PF01690.12 CDI73853.1 - 3 6.8 21.2 4.1 6.4 14.7 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein PIG-U PF06728.8 CDI73854.1 - 0.092 11.5 2.2 2.2 7.0 0.0 2.2 2 0 0 2 2 2 0 GPI transamidase subunit PIG-U Ribosomal_60s PF00428.14 CDI73854.1 - 0.54 10.6 50.5 1.2 9.5 9.2 4.4 4 0 0 4 4 4 0 60s Acidic ribosomal protein DUF4483 PF14825.1 CDI73854.1 - 1.3 8.6 18.8 0.043 13.4 2.3 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4483) RskA PF10099.4 CDI73856.1 - 0.0062 16.2 3.4 0.0062 16.2 2.3 2.1 2 0 0 2 2 2 1 Anti-sigma-K factor rskA Zip PF02535.17 CDI73856.1 - 0.028 13.4 6.9 0.11 11.4 4.8 1.8 1 1 0 1 1 1 0 ZIP Zinc transporter Trp_oprn_chp PF09534.5 CDI73856.1 - 0.076 12.6 3.8 2.8 7.5 0.3 2.1 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) OSTbeta PF15048.1 CDI73856.1 - 0.36 10.9 7.5 0.61 10.1 1.0 2.2 2 0 0 2 2 2 0 Organic solute transporter subunit beta protein DUF755 PF05501.6 CDI73856.1 - 0.64 10.0 39.5 0.052 13.5 13.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF755) FHIPEP PF00771.15 CDI73856.1 - 1.2 7.3 8.7 1.2 7.3 0.5 2.0 2 0 0 2 2 2 0 FHIPEP family FxsA PF04186.8 CDI73856.1 - 1.4 8.5 6.5 3.4 7.2 0.8 2.3 2 0 0 2 2 2 0 FxsA cytoplasmic membrane protein Presenilin PF01080.12 CDI73856.1 - 1.8 7.2 8.5 2.7 6.7 5.9 1.2 1 0 0 1 1 1 0 Presenilin Peptidase_S15 PF02129.13 CDI73856.1 - 1.9 7.8 8.0 2.8 7.2 1.0 2.2 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) Peptidase_S49_N PF08496.5 CDI73856.1 - 2.1 8.1 11.1 1.6 8.4 1.6 2.1 2 0 0 2 2 2 0 Peptidase family S49 N-terminal DUF533 PF04391.7 CDI73856.1 - 2.8 7.2 19.8 0.23 10.8 2.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF533) SeqA PF03925.8 CDI73856.1 - 2.9 7.5 11.7 4.2 7.0 2.3 2.2 2 0 0 2 2 2 0 SeqA protein DUF3357 PF11837.3 CDI73856.1 - 2.9 7.7 10.4 1.2 9.0 1.2 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF3357) Apc15p PF05841.6 CDI73856.1 - 3.1 8.5 24.5 2.8 8.6 4.2 2.3 2 0 0 2 2 2 0 Apc15p protein Afi1 PF07792.7 CDI73856.1 - 3.4 7.6 12.5 5.2 7.0 1.8 2.2 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking PAT1 PF09770.4 CDI73856.1 - 3.5 5.7 37.0 0.25 9.5 6.6 2.0 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 AAA_23 PF13476.1 CDI73856.1 - 3.6 7.8 13.0 2.1 8.6 0.2 2.1 2 0 0 2 2 2 0 AAA domain Band_3_cyto PF07565.8 CDI73856.1 - 3.8 6.9 15.1 4.3 6.7 2.2 2.1 2 0 0 2 2 2 0 Band 3 cytoplasmic domain RAP1 PF07218.6 CDI73856.1 - 3.9 5.4 4.7 4.5 5.2 3.2 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) SpoIIIAH PF12685.2 CDI73856.1 - 8.1 5.8 13.1 56 3.1 9.1 1.9 1 1 0 1 1 1 0 SpoIIIAH-like protein DBC1 PF14443.1 CDI73856.1 - 9 5.8 8.8 2.2 7.7 0.1 2.3 2 0 0 2 2 2 0 DBC1 Oleosin PF01277.12 CDI73856.1 - 9.5 5.8 6.4 29 4.2 0.1 2.2 2 0 0 2 2 2 0 Oleosin DUF3115 PF11312.3 CDI73856.1 - 9.5 4.9 14.4 0.056 12.2 3.2 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3115) Med15 PF09606.5 CDI73856.1 - 9.8 4.2 50.6 0.11 10.7 11.1 2.0 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal Pex16 PF08610.5 CDI73856.1 - 9.9 5.0 16.4 3.5 6.5 2.7 2.1 2 0 0 2 2 2 0 Peroxisomal membrane protein (Pex16) EphA2_TM PF14575.1 CDI73857.1 - 1.9e-05 24.9 0.9 0.12 12.7 0.0 2.1 2 0 0 2 2 2 2 Ephrin type-A receptor 2 transmembrane domain DUF3357 PF11837.3 CDI73857.1 - 2.8e-05 23.9 3.5 0.064 13.1 0.2 2.1 1 1 1 2 2 2 2 Domain of unknown function (DUF3357) SIT PF15330.1 CDI73857.1 - 5.8e-05 23.1 8.6 0.017 15.2 0.3 2.3 2 0 0 2 2 2 2 SHP2-interacting transmembrane adaptor protein, SIT OppC_N PF12911.2 CDI73857.1 - 8e-05 21.9 0.3 0.38 10.1 0.0 2.3 2 0 0 2 2 2 2 N-terminal TM domain of oligopeptide transport permease C DUF3530 PF12048.3 CDI73857.1 - 0.00021 20.3 21.2 0.0093 14.9 3.9 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF3530) Conotoxin PF02950.12 CDI73857.1 - 0.00023 21.8 9.8 0.096 13.4 0.6 2.2 2 0 0 2 2 2 2 Conotoxin Brevenin PF03032.10 CDI73857.1 - 0.00031 20.5 5.6 0.11 12.3 0.4 2.2 2 0 0 2 2 2 2 Brevenin/esculentin/gaegurin/rugosin family Rer1 PF03248.8 CDI73857.1 - 0.001 18.7 6.3 0.17 11.4 0.4 2.0 2 0 0 2 2 2 2 Rer1 family NicO PF03824.11 CDI73857.1 - 0.0013 18.1 0.4 0.9 8.8 0.1 2.0 2 0 0 2 2 2 1 High-affinity nickel-transport protein SpoIIIAH PF12685.2 CDI73857.1 - 0.0014 18.1 2.2 0.78 9.2 0.1 2.0 2 0 0 2 2 2 2 SpoIIIAH-like protein DUF1510 PF07423.6 CDI73857.1 - 0.0014 18.0 2.6 0.64 9.3 0.2 2.0 2 0 0 2 2 2 2 Protein of unknown function (DUF1510) DUF2973 PF11189.3 CDI73857.1 - 0.0015 18.2 3.4 0.35 10.6 0.3 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF2973) DUF843 PF05814.6 CDI73857.1 - 0.0018 18.0 0.6 1.2 8.9 0.1 2.1 2 0 0 2 2 2 1 Baculovirus protein of unknown function (DUF843) DUF4199 PF13858.1 CDI73857.1 - 0.0019 18.1 4.5 0.23 11.3 0.3 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF4199) GspL_C PF12693.2 CDI73857.1 - 0.002 17.9 34.9 0.024 14.3 8.9 2.3 2 0 0 2 2 2 2 GspL periplasmic domain OAD_gamma PF04277.8 CDI73857.1 - 0.002 18.4 0.1 2.8 8.4 0.0 2.1 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain GRP PF07172.6 CDI73857.1 - 0.0022 18.4 3.7 0.58 10.6 0.1 2.1 2 0 0 2 2 2 1 Glycine rich protein family DUF1183 PF06682.7 CDI73857.1 - 0.0028 17.3 1.4 0.0045 16.6 1.0 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF1183) Sex_peptide PF08138.6 CDI73857.1 - 0.0028 17.4 2.5 1.1 9.2 0.1 2.2 2 0 0 2 2 2 1 Sex peptide (SP) family UPF0542 PF15086.1 CDI73857.1 - 0.0056 16.3 1.2 1.7 8.4 0.1 2.2 2 0 0 2 2 2 0 Uncharacterised protein family UPF0542 Reticulon PF02453.12 CDI73857.1 - 0.0058 16.2 1.9 0.69 9.5 0.2 2.1 2 0 0 2 2 2 1 Reticulon DUF4366 PF14283.1 CDI73857.1 - 0.0062 15.9 2.0 0.011 15.2 1.1 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4366) CcmH PF03918.9 CDI73857.1 - 0.0064 15.5 5.8 0.31 10.0 0.3 2.1 2 0 0 2 2 2 2 Cytochrome C biogenesis protein UPF0182 PF03699.8 CDI73857.1 - 0.0071 14.3 0.7 0.0085 14.0 0.5 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0182) DUF3278 PF11683.3 CDI73857.1 - 0.0089 16.0 1.8 1.6 8.7 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3278) DUF2149 PF09919.4 CDI73857.1 - 0.0092 16.0 5.1 1.2 9.2 0.6 2.1 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2149) FtsL PF04999.8 CDI73857.1 - 0.0093 15.6 12.0 0.17 11.5 3.2 2.1 2 0 0 2 2 2 2 Cell division protein FtsL ABC2_membrane_2 PF12679.2 CDI73857.1 - 0.0095 14.8 4.2 0.42 9.4 0.2 2.0 2 0 0 2 2 2 1 ABC-2 family transporter protein Pex24p PF06398.6 CDI73857.1 - 0.011 14.6 1.6 1.8 7.2 0.1 2.0 1 1 1 2 2 2 0 Integral peroxisomal membrane peroxin DUF2514 PF10721.4 CDI73857.1 - 0.012 15.2 6.4 0.42 10.2 0.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2514) FGF-BP1 PF06473.7 CDI73857.1 - 0.015 14.8 8.5 0.57 9.7 0.4 2.1 2 0 0 2 2 2 0 FGF binding protein 1 (FGF-BP1) Cytochrom_B_N PF00033.14 CDI73857.1 - 0.02 14.2 0.1 2.8 7.2 0.0 2.0 2 0 0 2 2 2 0 Cytochrome b(N-terminal)/b6/petB TctB PF07331.6 CDI73857.1 - 0.02 14.5 0.0 4.9 6.7 0.0 2.0 1 1 1 2 2 2 0 Tripartite tricarboxylate transporter TctB family Zip PF02535.17 CDI73857.1 - 0.021 13.8 0.2 0.026 13.5 0.1 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter TRP PF06011.7 CDI73857.1 - 0.022 13.3 1.0 2.5 6.5 0.0 2.0 2 0 0 2 2 2 0 Transient receptor potential (TRP) ion channel PSK PF06404.7 CDI73857.1 - 0.023 15.4 6.1 2 9.2 0.8 2.2 2 0 0 2 2 2 0 Phytosulfokine precursor protein (PSK) KASH PF10541.4 CDI73857.1 - 0.025 14.4 7.4 0.79 9.6 0.7 2.2 2 0 0 2 2 2 0 Nuclear envelope localisation domain DUF3394 PF11874.3 CDI73857.1 - 0.032 13.7 6.1 0.37 10.3 0.4 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF3394) Tmemb_9 PF05434.6 CDI73857.1 - 0.039 13.6 6.5 0.62 9.8 0.7 2.1 2 0 0 2 2 2 0 TMEM9 DUF4220 PF13968.1 CDI73857.1 - 0.042 12.9 2.0 0.057 12.5 1.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4220) 60KD_IMP PF02096.15 CDI73857.1 - 0.042 13.4 18.3 0.3 10.7 3.0 2.2 1 1 1 2 2 2 0 60Kd inner membrane protein Peptidase_M56 PF05569.6 CDI73857.1 - 0.045 12.7 2.0 0.056 12.4 1.4 1.1 1 0 0 1 1 1 0 BlaR1 peptidase M56 DUF2782 PF11191.3 CDI73857.1 - 0.047 13.6 5.4 1.5 8.8 0.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2782) PIRT PF15099.1 CDI73857.1 - 0.049 12.8 13.5 0.34 10.1 1.8 2.1 2 0 0 2 2 2 0 Phosphoinositide-interacting protein family PepSY_2 PF13670.1 CDI73857.1 - 0.053 13.4 0.7 9.9 6.1 0.0 2.1 2 0 0 2 2 2 0 Peptidase propeptide and YPEB domain DUF1430 PF07242.6 CDI73857.1 - 0.065 13.3 0.8 9.9 6.3 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1430) DUF2269 PF10027.4 CDI73857.1 - 0.066 12.9 4.0 0.16 11.7 0.1 2.0 1 1 1 2 2 2 0 Predicted integral membrane protein (DUF2269) YjgP_YjgQ PF03739.9 CDI73857.1 - 0.074 11.7 7.4 0.37 9.4 0.4 2.0 2 0 0 2 2 2 0 Predicted permease YjgP/YjgQ family Wound_ind PF08186.6 CDI73857.1 - 0.075 12.9 2.0 3.8 7.4 0.1 2.2 2 0 0 2 2 2 0 Wound-inducible basic protein family DUF4320 PF14208.1 CDI73857.1 - 0.097 12.6 0.9 12 5.8 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4320) DUF506 PF04720.7 CDI73857.1 - 0.11 12.1 5.4 2.8 7.4 0.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF506) Rax2 PF12768.2 CDI73857.1 - 0.12 11.5 2.5 5.4 6.1 0.1 2.0 2 0 0 2 2 2 0 Cortical protein marker for cell polarity MFS_Mycoplasma PF07672.8 CDI73857.1 - 0.12 11.4 5.6 2.2 7.3 0.2 2.0 2 0 0 2 2 2 0 Mycoplasma MFS transporter NPH3 PF03000.9 CDI73857.1 - 0.14 11.6 5.1 2.3 7.6 0.4 2.1 2 0 0 2 2 2 0 NPH3 family Tetraspannin PF00335.15 CDI73857.1 - 0.15 11.3 2.5 6.1 6.0 0.1 2.0 2 0 0 2 2 2 0 Tetraspanin family ETRAMP PF09716.5 CDI73857.1 - 0.15 12.0 1.4 11 6.0 0.1 2.1 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) Endonuc_Holl PF10107.4 CDI73857.1 - 0.18 11.4 8.4 2.1 8.0 0.2 2.0 2 0 0 2 2 2 0 Endonuclease related to archaeal Holliday junction resolvase Ly49 PF08391.5 CDI73857.1 - 0.19 11.8 18.0 0.89 9.7 2.5 2.2 2 0 0 2 2 2 0 Ly49-like protein, N-terminal region DBC1 PF14443.1 CDI73857.1 - 0.21 11.1 8.3 1.6 8.2 0.6 2.1 2 0 0 2 2 2 0 DBC1 Neurensin PF14927.1 CDI73857.1 - 0.22 10.8 5.0 4.8 6.5 0.3 2.2 2 0 0 2 2 2 0 Neurensin TMEM154 PF15102.1 CDI73857.1 - 0.24 11.0 14.5 1.5 8.4 2.2 2.1 1 1 0 2 2 2 0 TMEM154 protein family DUF2899 PF11449.3 CDI73857.1 - 0.28 10.3 0.9 0.51 9.4 0.7 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2899) DUF4149 PF13664.1 CDI73857.1 - 0.31 11.0 2.1 16 5.6 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4149) DUF788 PF05620.6 CDI73857.1 - 0.32 10.8 8.9 2.9 7.7 0.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF788) RskA PF10099.4 CDI73857.1 - 0.34 10.6 9.3 1.9 8.1 0.9 2.2 1 1 1 2 2 2 0 Anti-sigma-K factor rskA Enkurin PF13864.1 CDI73857.1 - 0.44 10.7 14.9 0.87 9.8 1.5 2.1 2 0 0 2 2 2 0 Calmodulin-binding Selenoprotein_S PF06936.6 CDI73857.1 - 0.48 9.9 11.1 2.8 7.4 0.6 2.1 2 0 0 2 2 2 0 Selenoprotein S (SelS) m04gp34like PF12216.3 CDI73857.1 - 0.6 9.4 2.7 13 5.0 0.1 2.0 1 1 1 2 2 2 0 Immune evasion protein DUF4564 PF15169.1 CDI73857.1 - 0.62 9.7 4.4 8.4 6.0 0.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4564) Scs3p PF10261.4 CDI73857.1 - 0.65 8.9 6.2 1.3 7.9 0.7 2.0 1 1 1 2 2 2 0 Inositol phospholipid synthesis and fat-storage-inducing TM DUF1418 PF07214.7 CDI73857.1 - 0.67 9.6 3.0 17 5.1 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1418) Zn_peptidase PF04228.8 CDI73857.1 - 0.71 9.0 14.0 1.6 7.8 1.7 2.0 1 1 1 2 2 2 0 Putative neutral zinc metallopeptidase Haem_bd PF14376.1 CDI73857.1 - 0.72 9.5 10.2 2.5 7.7 0.6 2.2 2 0 0 2 2 2 0 Haem-binding domain DUF1840 PF08895.6 CDI73857.1 - 0.82 9.7 7.8 7 6.7 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1840) Potyvirid-P3 PF13608.1 CDI73857.1 - 0.91 8.5 13.7 1.9 7.5 1.6 2.0 1 1 1 2 2 2 0 Protein P3 of Potyviral polyprotein Virul_fac_BrkB PF03631.10 CDI73857.1 - 0.98 8.7 9.6 4.9 6.4 2.5 2.0 2 0 0 2 2 2 0 Virulence factor BrkB Herpes_UL3 PF03369.8 CDI73857.1 - 0.99 9.3 4.8 1.8 8.5 0.4 2.0 2 0 0 2 2 2 0 Herpesvirus UL3 protein CLPTM1 PF05602.7 CDI73857.1 - 1 8.0 7.7 1.6 7.3 0.5 2.0 1 1 1 2 2 2 0 Cleft lip and palate transmembrane protein 1 (CLPTM1) DUF808 PF05661.7 CDI73857.1 - 1 8.1 3.4 6.6 5.4 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF808) SHR3_chaperone PF08229.6 CDI73857.1 - 1.2 8.0 11.8 2.2 7.1 1.1 2.1 2 0 0 2 2 2 0 ER membrane protein SH3 FAM176 PF14851.1 CDI73857.1 - 1.3 8.6 7.8 5.3 6.6 0.5 2.1 1 1 1 2 2 2 0 FAM176 family eIF-3_zeta PF05091.7 CDI73857.1 - 1.4 7.4 10.3 1.9 6.9 7.1 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) 7TM_GPCR_Srv PF10323.4 CDI73857.1 - 1.4 7.9 3.7 14 4.6 0.3 2.1 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srv DUF4064 PF13273.1 CDI73857.1 - 1.4 9.0 7.6 5.1 7.2 0.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF4064) DUF4316 PF14195.1 CDI73857.1 - 1.4 9.0 6.3 10 6.2 0.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4316) Smr PF01713.16 CDI73857.1 - 1.6 8.9 4.2 15 5.8 0.1 2.2 2 0 0 2 2 2 0 Smr domain 7tm_1 PF00001.16 CDI73857.1 - 1.7 7.7 4.6 9.8 5.2 3.2 1.8 1 1 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) FxsA PF04186.8 CDI73857.1 - 1.8 8.2 11.7 3.3 7.3 0.8 2.1 2 0 0 2 2 2 0 FxsA cytoplasmic membrane protein Anoctamin PF04547.7 CDI73857.1 - 2.1 6.8 7.9 2.9 6.4 5.5 1.2 1 0 0 1 1 1 0 Calcium-activated chloride channel DUF4080 PF13311.1 CDI73857.1 - 2.2 8.2 13.0 3.3 7.6 2.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF4080) DUF2489 PF10675.4 CDI73857.1 - 2.5 7.7 22.0 3.6 7.2 5.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2489) tRNA_synt_1c_R2 PF04557.10 CDI73857.1 - 2.8 8.6 7.8 2.2 9.0 0.7 2.1 2 0 0 2 2 2 0 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 Rpp20 PF12328.3 CDI73857.1 - 3.1 7.4 7.5 6.4 6.4 0.1 2.1 2 0 0 2 2 2 0 Rpp20 subunit of nuclear RNase MRP and P ABC_membrane_3 PF13748.1 CDI73857.1 - 3.2 6.7 7.0 7.5 5.5 1.3 2.0 2 0 0 2 2 2 0 ABC transporter transmembrane region DUF3301 PF11743.3 CDI73857.1 - 3.3 7.3 10.0 5.8 6.5 1.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3301) DivIC PF04977.10 CDI73857.1 - 3.3 7.2 29.5 4.7 6.7 8.0 2.1 2 0 0 2 2 2 0 Septum formation initiator BRF1 PF07741.8 CDI73857.1 - 3.9 7.7 12.0 6.2 7.1 1.2 2.1 2 0 0 2 2 2 0 Brf1-like TBP-binding domain RNA_pol_Rpc4 PF05132.9 CDI73857.1 - 3.9 7.4 11.3 7.3 6.5 1.5 2.1 2 0 0 2 2 2 0 RNA polymerase III RPC4 Agouti PF05039.7 CDI73857.1 - 4.4 7.7 8.0 8 6.8 1.0 2.1 2 0 0 2 2 2 0 Agouti protein RAB3GAP2_N PF14655.1 CDI73857.1 - 4.8 6.0 24.4 1.1 8.1 5.3 2.0 1 1 1 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus APC_CDC26 PF10471.4 CDI73857.1 - 6.1 7.6 35.2 8.6 7.1 9.1 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit 1 PulG PF11773.3 CDI73857.1 - 6.3 6.6 21.0 4.4 7.1 4.7 2.5 2 0 0 2 2 2 0 Type II secretory pathway pseudopilin DUF2227 PF09988.4 CDI73857.1 - 7.8 6.1 6.5 16 5.0 0.9 2.0 2 0 0 2 2 2 0 Uncharacterized metal-binding protein (DUF2227) RED_N PF07808.8 CDI73857.1 - 7.8 5.6 20.6 2.6 7.1 2.8 2.0 2 0 0 2 2 2 0 RED-like protein N-terminal region YfhO PF09586.5 CDI73857.1 - 8.1 4.3 13.4 54 1.6 9.3 1.8 1 1 0 1 1 1 0 Bacterial membrane protein YfhO Neur_chan_memb PF02932.11 CDI73857.1 - 8.2 6.2 10.4 14 5.4 7.2 1.4 1 1 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region RRP14 PF15459.1 CDI73857.1 - 8.8 6.4 15.8 10 6.2 2.6 2.2 2 0 0 2 2 2 0 60S ribosome biogenesis protein Rrp14 Claudin_2 PF13903.1 CDI73857.1 - 9.3 5.9 13.2 2.2 7.9 1.1 2.2 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction DUF4643 PF15485.1 CDI73857.1 - 9.6 5.5 16.4 3.7 6.9 3.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4643) TCP PF03634.8 CDI73858.1 - 9.6 6.5 48.6 8.3 6.7 3.9 3.3 3 0 0 3 3 3 0 TCP family transcription factor DUF1892 PF08987.5 CDI73859.1 - 0.42 10.6 2.8 30 4.6 0.2 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1892) DUF897 PF05982.7 CDI73859.1 - 4.9 5.8 6.8 3.8e+02 -0.4 4.7 2.8 1 1 0 1 1 1 0 Domain of unknown function (DUF897) Myosin_tail_1 PF01576.14 CDI73860.1 - 0.0039 14.9 21.7 0.0044 14.8 15.1 1.0 1 0 0 1 1 1 1 Myosin tail DUF2353 PF09789.4 CDI73860.1 - 0.0053 16.0 14.0 0.0064 15.7 9.7 1.0 1 0 0 1 1 1 1 Uncharacterized coiled-coil protein (DUF2353) MbeD_MobD PF04899.7 CDI73860.1 - 0.0079 16.0 10.9 0.048 13.5 0.3 2.2 1 1 1 2 2 2 1 MbeD/MobD like FH2 PF02181.18 CDI73860.1 - 0.028 13.2 12.5 0.038 12.8 8.7 1.1 1 0 0 1 1 1 0 Formin Homology 2 Domain Talin_middle PF09141.5 CDI73860.1 - 0.03 13.9 3.1 0.034 13.8 2.1 1.1 1 0 0 1 1 1 0 Talin, middle domain NPV_P10 PF05531.7 CDI73860.1 - 0.036 14.3 2.3 0.046 13.9 1.6 1.4 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Laminin_II PF06009.7 CDI73860.1 - 0.14 11.8 10.0 0.13 11.9 6.2 1.5 1 1 1 2 2 2 0 Laminin Domain II Cas_DxTHG PF09455.5 CDI73860.1 - 0.15 11.2 2.2 0.17 10.9 1.6 1.1 1 0 0 1 1 1 0 CRISPR-associated (Cas) DxTHG family Nup54 PF13874.1 CDI73860.1 - 0.19 11.4 13.3 1.3 8.6 2.3 2.2 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 Reo_sigmaC PF04582.7 CDI73860.1 - 0.23 10.6 1.9 0.23 10.5 1.3 1.1 1 0 0 1 1 1 0 Reovirus sigma C capsid protein DUF2115 PF09888.4 CDI73860.1 - 0.25 11.4 3.0 0.29 11.2 2.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2115) DNA_topoisoIV PF00521.15 CDI73860.1 - 0.46 9.2 11.2 0.5 9.1 7.8 1.0 1 0 0 1 1 1 0 DNA gyrase/topoisomerase IV, subunit A DUF1664 PF07889.7 CDI73860.1 - 0.48 10.2 6.2 1.1 9.0 0.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF1501 PF07394.7 CDI73860.1 - 0.48 9.2 5.6 0.53 9.0 3.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) DUF853 PF05872.7 CDI73860.1 - 0.58 8.4 4.5 0.6 8.4 3.1 1.0 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) Phage_GPO PF05929.6 CDI73860.1 - 0.63 9.2 10.9 0.67 9.1 7.6 1.1 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase Fungal_trans_2 PF11951.3 CDI73860.1 - 0.63 8.5 3.0 0.73 8.3 2.1 1.2 1 0 0 1 1 1 0 Fungal specific transcription factor domain Plasmid_stabil PF05016.9 CDI73860.1 - 0.7 10.3 3.4 1.3 9.4 2.2 1.6 1 1 1 2 2 2 0 Plasmid stabilisation system protein DUF2205 PF10224.4 CDI73860.1 - 0.89 9.1 14.2 1 8.9 5.1 2.2 1 1 1 2 2 2 0 Predicted coiled-coil protein (DUF2205) Muted PF14942.1 CDI73860.1 - 0.91 9.3 14.3 1.2 9.0 9.9 1.2 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein CALCOCO1 PF07888.6 CDI73860.1 - 0.98 7.6 20.3 1.8 6.7 10.8 1.6 1 1 1 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like DUF2937 PF11157.3 CDI73860.1 - 0.99 8.7 7.1 1.3 8.2 4.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2937) ComGG PF14173.1 CDI73860.1 - 0.99 9.6 12.4 0.15 12.3 1.5 2.2 1 1 1 2 2 2 0 ComG operon protein 7 SpoVR PF04293.8 CDI73860.1 - 1.4 7.2 6.9 1.6 7.0 4.8 1.0 1 0 0 1 1 1 0 SpoVR like protein DUF607 PF04678.8 CDI73860.1 - 1.4 8.8 6.3 2 8.3 4.4 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF607 ATG16 PF08614.6 CDI73860.1 - 1.4 8.6 19.6 0.19 11.5 6.7 1.9 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) DUF2229 PF09989.4 CDI73860.1 - 1.4 8.2 6.7 1.8 7.9 4.6 1.2 1 0 0 1 1 1 0 CoA enzyme activase uncharacterised domain (DUF2229) Spc7 PF08317.6 CDI73860.1 - 1.6 7.3 14.1 2 7.0 9.8 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein FemAB PF02388.11 CDI73860.1 - 1.6 7.3 8.4 1.8 7.1 5.8 1.1 1 0 0 1 1 1 0 FemAB family IncA PF04156.9 CDI73860.1 - 1.8 8.1 25.9 25 4.4 18.2 1.9 1 1 0 1 1 1 0 IncA protein YlqD PF11068.3 CDI73860.1 - 2.1 8.4 17.5 1.5 8.8 11.2 1.4 1 1 0 1 1 1 0 YlqD protein FUSC PF04632.7 CDI73860.1 - 2.4 6.5 8.3 2.3 6.5 5.7 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF948 PF06103.6 CDI73860.1 - 2.5 8.0 4.7 8.1 6.3 0.9 2.3 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF3287 PF11690.3 CDI73860.1 - 2.6 8.1 5.8 4.2 7.4 0.8 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3287) Exonuc_VII_L PF02601.10 CDI73860.1 - 2.9 7.0 8.6 3.1 6.8 6.0 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Striatin PF08232.7 CDI73860.1 - 3.1 8.0 16.8 16 5.7 1.6 2.2 1 1 1 2 2 2 0 Striatin family DUF972 PF06156.8 CDI73860.1 - 3.8 7.9 16.2 7.7 6.9 4.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF972) V_ATPase_I PF01496.14 CDI73860.1 - 4.1 5.1 10.5 4.5 5.0 7.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Fmp27_WPPW PF10359.4 CDI73860.1 - 4.4 5.6 9.5 4.5 5.5 6.6 1.2 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain DUF342 PF03961.8 CDI73860.1 - 4.4 5.5 11.9 4.9 5.4 8.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF2514 PF10721.4 CDI73860.1 - 4.5 6.9 18.4 14 5.3 12.5 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2514) DUF4047 PF13256.1 CDI73860.1 - 4.6 7.2 9.3 5.4 7.0 6.2 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4047) DUF4446 PF14584.1 CDI73860.1 - 5.4 6.8 10.7 6.8 6.5 2.4 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF4446) Prominin PF05478.6 CDI73860.1 - 5.8 4.3 8.4 6.4 4.1 5.8 1.0 1 0 0 1 1 1 0 Prominin ADIP PF11559.3 CDI73860.1 - 6.8 6.5 18.6 5.7 6.8 12.0 1.6 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding GrpE PF01025.14 CDI73860.1 - 7.5 6.0 18.5 14 5.1 12.8 1.4 1 1 0 1 1 1 0 GrpE Ax_dynein_light PF10211.4 CDI73860.1 - 7.6 6.3 17.4 89 2.8 11.8 2.0 1 1 0 1 1 1 0 Axonemal dynein light chain Spc24 PF08286.6 CDI73860.1 - 8 6.1 15.8 2.2 7.9 5.0 2.2 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 Syntaxin-6_N PF09177.6 CDI73860.1 - 9.2 6.7 10.2 4.3 7.8 3.0 2.1 1 1 1 2 2 2 0 Syntaxin 6, N-terminal IF-2 PF11987.3 CDI73862.1 - 2.2e-10 40.4 0.2 8e-06 25.6 0.0 2.5 2 0 0 2 2 2 2 Translation-initiation factor 2 DUF1107 PF06526.7 CDI73862.1 - 0.13 12.0 0.0 0.87 9.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1107) Biotin_lipoyl_2 PF13533.1 CDI73862.1 - 0.22 11.1 3.3 14 5.4 0.0 3.1 3 0 0 3 3 3 0 Biotin-lipoyl like MSP1_C PF07462.6 CDI73862.1 - 0.46 8.8 4.9 0.68 8.2 3.4 1.2 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus DUF2057 PF09829.4 CDI73862.1 - 0.74 9.4 12.3 0.026 14.1 3.7 1.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2057) CAF-1_p150 PF11600.3 CDI73863.1 - 0.0019 17.6 41.2 0.0025 17.2 28.5 1.1 1 0 0 1 1 1 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal SprA-related PF12118.3 CDI73863.1 - 0.031 13.6 67.7 0.036 13.4 46.9 1.0 1 0 0 1 1 1 0 SprA-related family PAT1 PF09770.4 CDI73863.1 - 0.038 12.2 57.1 0.039 12.1 39.6 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Med15 PF09606.5 CDI73863.1 - 0.063 11.4 77.2 0.063 11.4 53.5 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal RR_TM4-6 PF06459.7 CDI73863.1 - 0.43 10.4 25.5 0.59 9.9 17.7 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Tim54 PF11711.3 CDI73863.1 - 1 7.8 16.8 1.1 7.8 11.6 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Nop53 PF07767.6 CDI73863.1 - 1.6 7.6 33.8 1.8 7.4 23.4 1.0 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) DUF2052 PF09747.4 CDI73863.1 - 1.8 8.4 33.3 1.9 8.3 23.1 1.2 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) Peptidase_S15 PF02129.13 CDI73863.1 - 4.5 6.6 18.9 5.7 6.2 13.1 1.3 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) DUF3987 PF13148.1 CDI73863.1 - 5.7 5.3 18.8 6.4 5.2 13.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) AAA_23 PF13476.1 CDI73863.1 - 5.9 7.1 36.2 6.8 6.9 25.1 1.1 1 0 0 1 1 1 0 AAA domain eIF-3_zeta PF05091.7 CDI73863.1 - 6.6 5.2 38.8 6.9 5.1 26.9 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Peptidase_U57 PF05582.7 CDI73863.1 - 8.6 5.2 18.9 11 4.9 13.1 1.3 1 0 0 1 1 1 0 YabG peptidase U57 Mem_trans PF03547.13 CDI73866.1 - 3.8 5.6 7.1 0.52 8.5 0.4 2.1 2 0 0 2 2 2 0 Membrane transport protein Suf PF05843.9 CDI73866.1 - 3.9 7.1 17.5 0.26 10.9 6.2 2.1 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) HEAT PF02985.17 CDI73867.1 - 2.6e-05 23.9 8.1 0.49 10.6 0.0 5.0 4 0 0 4 4 4 3 HEAT repeat FimP PF09766.4 CDI73867.1 - 0.00056 19.0 7.9 0.00056 19.0 5.5 7.3 5 2 2 7 7 7 1 Fms-interacting protein BAF1_ABF1 PF04684.8 CDI73867.1 - 0.0035 16.2 17.4 0.0035 16.2 12.0 10.2 6 2 3 9 9 9 1 BAF1 / ABF1 chromatin reorganising factor RIC3 PF15361.1 CDI73867.1 - 0.012 15.8 3.0 0.012 15.8 2.1 7.7 10 0 0 10 10 10 0 Resistance to inhibitors of cholinesterase homologue 3 CompInhib_SCIN PF11546.3 CDI73868.1 - 0.055 13.3 8.0 0.061 13.1 5.6 1.0 1 0 0 1 1 1 0 Staphylococcal complement inhibitor SCIN Ribosomal_60s PF00428.14 CDI73869.1 - 0.028 14.8 26.1 0.074 13.4 3.6 3.4 3 0 0 3 3 3 0 60s Acidic ribosomal protein TPR_11 PF13414.1 CDI73873.1 - 7.2e-06 25.5 3.6 7.2e-06 25.5 2.5 3.4 3 1 0 3 3 3 1 TPR repeat TPR_19 PF14559.1 CDI73873.1 - 0.00032 20.9 14.1 0.0019 18.5 1.2 4.1 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.1 CDI73873.1 - 0.0016 18.4 0.9 0.0085 16.2 0.0 2.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 CDI73873.1 - 0.0023 18.4 2.2 0.0023 18.4 1.5 6.2 6 1 1 7 7 7 2 Tetratricopeptide repeat TPR_16 PF13432.1 CDI73873.1 - 0.014 16.0 3.2 0.014 16.0 2.2 5.7 5 1 0 5 5 5 0 Tetratricopeptide repeat TPR_2 PF07719.12 CDI73873.1 - 0.017 15.0 0.4 0.017 15.0 0.3 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.23 CDI73873.1 - 0.11 12.1 6.7 0.37 10.4 0.1 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat Hypoth_Ymh PF09509.5 CDI73874.1 - 0.071 12.7 0.6 2.8 7.5 0.1 2.9 2 1 0 2 2 2 0 Protein of unknown function (Hypoth_ymh) B PF02216.11 CDI73875.1 - 0.11 12.2 0.0 0.24 11.1 0.0 1.5 1 0 0 1 1 1 0 B domain Plexin_cytopl PF08337.7 CDI73882.1 - 0.0031 15.9 2.4 0.0047 15.3 1.7 1.3 1 0 0 1 1 1 1 Plexin cytoplasmic RasGAP domain DUF4602 PF15375.1 CDI73882.1 - 0.0069 16.4 20.4 0.021 14.9 8.8 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4602) dsDNA_bind PF01984.15 CDI73882.1 - 0.0097 15.8 14.2 0.0097 15.8 9.8 3.1 2 1 1 3 3 2 1 Double-stranded DNA-binding domain Ycf1 PF05758.7 CDI73882.1 - 0.043 11.5 9.7 0.05 11.3 6.7 1.1 1 0 0 1 1 1 0 Ycf1 Presenilin PF01080.12 CDI73882.1 - 0.11 11.2 5.3 0.14 10.9 3.7 1.2 1 0 0 1 1 1 0 Presenilin Zip PF02535.17 CDI73882.1 - 0.26 10.2 5.7 0.41 9.6 3.9 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter FYDLN_acid PF09538.5 CDI73882.1 - 0.51 10.9 9.3 0.25 11.9 3.6 1.9 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) PAT1 PF09770.4 CDI73882.1 - 0.52 8.4 53.4 0.62 8.2 37.0 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Baculo_PP31 PF05311.6 CDI73882.1 - 1.1 8.4 17.4 0.049 12.8 6.2 2.0 2 0 0 2 2 2 0 Baculovirus 33KDa late protein (PP31) SAPS PF04499.10 CDI73882.1 - 1.2 7.6 12.1 1.5 7.3 8.4 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Ebola_NP PF05505.7 CDI73882.1 - 1.3 7.0 17.6 1.6 6.7 12.2 1.0 1 0 0 1 1 1 0 Ebola nucleoprotein AIF_C PF14721.1 CDI73882.1 - 1.4 9.1 14.7 0.36 11.0 6.0 2.0 2 0 0 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term SID-1_RNA_chan PF13965.1 CDI73882.1 - 3.8 5.5 5.1 5.5 5.0 3.5 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Pex14_N PF04695.8 CDI73882.1 - 4.4 7.3 30.1 0.54 10.2 13.0 2.3 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DHHW PF14286.1 CDI73882.1 - 4.7 6.4 11.3 0.28 10.4 4.1 1.6 2 0 0 2 2 2 0 DHHW protein DUF4094 PF13334.1 CDI73882.1 - 4.7 7.6 18.6 0.85 10.0 7.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4094) FNIP_N PF14636.1 CDI73882.1 - 5 7.5 18.4 5.4 7.5 9.2 2.1 2 0 0 2 2 2 0 Folliculin-interacting protein N-terminus DUF1764 PF08576.5 CDI73882.1 - 5.3 7.8 20.9 2.5 8.9 8.2 2.2 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF1764) DUF4658 PF15555.1 CDI73882.1 - 6 6.7 7.7 16 5.4 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4658) MDFI PF15316.1 CDI73882.1 - 6 6.8 8.1 1.3 9.0 2.3 1.9 2 0 0 2 2 2 0 MyoD family inhibitor Dynamin_N PF00350.18 CDI73882.1 - 6.1 6.6 8.8 0.98 9.2 2.9 1.8 2 0 0 2 2 2 0 Dynamin family F-protein PF00469.15 CDI73882.1 - 7.2 5.9 15.8 0.56 9.5 6.6 1.9 2 0 0 2 2 2 0 Negative factor, (F-Protein) or Nef SPX PF03105.14 CDI73882.1 - 9.7 5.8 14.5 15 5.2 10.1 1.2 1 0 0 1 1 1 0 SPX domain Peptidase_M17_N PF02789.12 CDI73883.1 - 7.5 6.3 14.9 4.2 7.1 0.4 2.2 2 0 0 2 2 2 0 Cytosol aminopeptidase family, N-terminal domain DUF1510 PF07423.6 CDI73886.1 - 0.24 10.7 16.4 0.29 10.4 11.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) AAA_23 PF13476.1 CDI73886.1 - 0.55 10.5 25.3 0.64 10.2 17.5 1.0 1 0 0 1 1 1 0 AAA domain SelP_N PF04592.9 CDI73886.1 - 0.78 9.0 34.4 0.99 8.7 23.9 1.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Rtf2 PF04641.7 CDI73886.1 - 1 8.5 19.7 1.2 8.2 13.7 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger SRP-alpha_N PF04086.8 CDI73886.1 - 1.5 8.1 17.4 1.8 7.8 12.1 1.0 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal DUF1183 PF06682.7 CDI73886.1 - 4.2 6.8 15.0 5.3 6.5 10.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) DUF4045 PF13254.1 CDI73886.1 - 7.1 5.7 18.8 8 5.6 13.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) FAM60A PF15396.1 CDI73886.1 - 8.8 6.0 22.4 10 5.8 15.5 1.0 1 0 0 1 1 1 0 Protein Family FAM60A DDHD PF02862.12 CDI73886.1 - 9.4 5.9 17.4 13 5.5 12.0 1.2 1 0 0 1 1 1 0 DDHD domain GPCR_chapero_1 PF11904.3 CDI73886.1 - 9.5 5.2 23.6 11 5.0 16.4 1.0 1 0 0 1 1 1 0 GPCR-chaperone MRP-S26 PF14943.1 CDI73887.1 - 0.01 15.4 5.9 0.014 14.9 4.1 1.3 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 MCPVI PF02993.9 CDI73887.1 - 0.01 15.9 13.7 0.013 15.6 9.5 1.2 1 0 0 1 1 1 0 Minor capsid protein VI DUF1644 PF07800.7 CDI73887.1 - 0.027 14.3 0.6 0.038 13.8 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1644) Band_3_cyto PF07565.8 CDI73887.1 - 0.032 13.7 2.1 0.033 13.6 1.5 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Suf PF05843.9 CDI73887.1 - 0.069 12.8 13.5 0.14 11.8 9.4 1.5 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) SIN1 PF05422.7 CDI73887.1 - 0.092 11.2 3.1 0.11 11.0 2.1 1.1 1 0 0 1 1 1 0 Stress-activated map kinase interacting protein 1 (SIN1) Macoilin PF09726.4 CDI73887.1 - 0.095 10.9 6.6 0.11 10.7 4.5 1.1 1 0 0 1 1 1 0 Transmembrane protein Draxin PF15550.1 CDI73887.1 - 0.096 12.3 4.2 0.11 12.1 2.9 1.1 1 0 0 1 1 1 0 Draxin Pex16 PF08610.5 CDI73887.1 - 0.11 11.5 3.3 0.12 11.3 2.3 1.1 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) Peptidase_S49_N PF08496.5 CDI73887.1 - 0.11 12.2 5.6 0.18 11.5 3.8 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Serinc PF03348.10 CDI73887.1 - 0.13 10.9 4.3 0.18 10.4 3.0 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) Mus7 PF09462.5 CDI73887.1 - 0.15 10.8 6.4 0.15 10.8 4.4 1.0 1 0 0 1 1 1 0 Mus7/MMS22 family MAT1 PF06391.8 CDI73887.1 - 0.17 11.4 11.7 0.23 11.0 8.1 1.2 1 0 0 1 1 1 0 CDK-activating kinase assembly factor MAT1 zf-DHHC PF01529.15 CDI73887.1 - 0.17 11.2 0.7 0.19 11.0 0.5 1.2 1 0 0 1 1 1 0 DHHC palmitoyltransferase FHIPEP PF00771.15 CDI73887.1 - 0.34 9.1 9.4 0.017 13.4 2.6 1.6 1 1 1 2 2 2 0 FHIPEP family DUF2331 PF10093.4 CDI73887.1 - 0.42 9.3 11.0 0.56 8.9 7.6 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2331) AAA_23 PF13476.1 CDI73887.1 - 0.6 10.4 10.7 0.72 10.1 7.4 1.1 1 0 0 1 1 1 0 AAA domain FimP PF09766.4 CDI73887.1 - 0.64 9.0 17.3 0.88 8.5 12.0 1.1 1 0 0 1 1 1 0 Fms-interacting protein Ndc1_Nup PF09531.5 CDI73887.1 - 0.7 8.2 8.4 0.8 8.0 5.8 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF3731 PF12531.3 CDI73887.1 - 0.79 9.1 15.5 0.44 10.0 9.3 1.5 1 1 0 1 1 1 0 DNA-K related protein PAT1 PF09770.4 CDI73887.1 - 1.1 7.3 29.9 1.4 7.0 20.7 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 OATP PF03137.15 CDI73887.1 - 1.2 7.1 7.1 1.7 6.6 5.0 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family MDFI PF15316.1 CDI73887.1 - 1.6 8.6 5.4 0.28 11.1 0.6 1.8 2 0 0 2 2 2 0 MyoD family inhibitor IER PF05760.7 CDI73887.1 - 1.7 8.4 15.9 2.3 8.0 11.0 1.1 1 0 0 1 1 1 0 Immediate early response protein (IER) Rpp20 PF12328.3 CDI73887.1 - 2.3 7.8 10.9 4.9 6.8 7.6 1.4 1 0 0 1 1 1 0 Rpp20 subunit of nuclear RNase MRP and P RAB3GAP2_N PF14655.1 CDI73887.1 - 3.4 6.5 10.7 5.1 5.9 7.4 1.2 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Borrelia_P83 PF05262.6 CDI73887.1 - 4.8 5.3 10.6 5.6 5.1 7.4 1.3 1 0 0 1 1 1 0 Borrelia P83/100 protein RED_N PF07808.8 CDI73887.1 - 6.4 5.9 15.0 9.7 5.3 10.4 1.2 1 0 0 1 1 1 0 RED-like protein N-terminal region SR-25 PF10500.4 CDI73888.1 - 1.2e-05 24.9 19.6 1.2e-05 24.9 13.6 14.6 9 4 4 14 14 14 3 Nuclear RNA-splicing-associated protein ABC2_membrane_2 PF12679.2 CDI73888.1 - 0.0045 15.8 0.1 0.0045 15.8 0.1 5.7 5 1 0 5 5 5 1 ABC-2 family transporter protein RCR PF12273.3 CDI73888.1 - 0.006 17.1 5.9 0.006 17.1 4.1 9.9 8 1 2 10 10 10 1 Chitin synthesis regulation, resistance to Congo red Gly-zipper_OmpA PF13436.1 CDI73889.1 - 0.0021 17.7 14.7 0.0021 17.7 10.2 5.2 4 1 1 5 5 5 1 Glycine-zipper containing OmpA-like membrane domain CAF-1_p150 PF11600.3 CDI73889.1 - 0.004 16.5 11.3 0.004 16.5 7.8 1.7 2 0 0 2 2 2 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal Spt20 PF12090.3 CDI73889.1 - 0.011 15.1 1.0 0.019 14.3 0.7 1.4 1 0 0 1 1 1 0 Spt20 family DUF4613 PF15390.1 CDI73889.1 - 0.23 9.5 13.1 0.33 9.0 9.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) Macoilin PF09726.4 CDI73889.1 - 0.36 9.0 22.9 0.57 8.3 15.8 1.4 1 0 0 1 1 1 0 Transmembrane protein Tom37_C PF11801.3 CDI73889.1 - 0.44 10.4 9.8 1 9.2 6.8 1.6 1 0 0 1 1 1 0 Tom37 C-terminal domain Peptidase_C14 PF00656.17 CDI73889.1 - 0.45 10.1 3.5 0.75 9.4 2.5 1.5 1 0 0 1 1 1 0 Caspase domain Peptidase_S64 PF08192.6 CDI73889.1 - 5.5 5.2 10.9 8 4.6 7.6 1.2 1 0 0 1 1 1 0 Peptidase family S64 Med15 PF09606.5 CDI73889.1 - 6.7 4.7 46.3 5.9 4.9 31.2 1.4 1 1 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal LMF1 PF06762.9 CDI73890.1 - 9.3e-17 60.8 0.7 1.5e-16 60.1 0.5 1.3 1 0 0 1 1 1 1 Lipase maturation factor DUF3633 PF12315.3 CDI73890.1 - 0.0058 15.9 0.6 0.0058 15.9 0.4 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3633) Secretin_N_2 PF07655.8 CDI73890.1 - 0.81 10.1 15.1 1.8 9.0 10.4 1.5 1 0 0 1 1 1 0 Secretin N-terminal domain DUF1635 PF07795.6 CDI73890.1 - 7.4 5.8 13.2 6.3 6.1 1.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1635) RskA PF10099.4 CDI73891.1 - 0.00046 19.9 4.8 0.00056 19.6 3.4 1.1 1 0 0 1 1 1 1 Anti-sigma-K factor rskA CAF-1_p150 PF11600.3 CDI73891.1 - 0.0029 17.0 17.4 0.0037 16.6 12.1 1.1 1 0 0 1 1 1 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal Corona_nucleoca PF00937.13 CDI73891.1 - 0.02 13.8 20.0 0.024 13.5 13.9 1.1 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein SprA-related PF12118.3 CDI73891.1 - 0.033 13.5 35.4 0.039 13.2 24.5 1.1 1 0 0 1 1 1 0 SprA-related family Ribosomal_60s PF00428.14 CDI73891.1 - 0.071 13.5 9.7 0.11 12.9 6.7 1.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein Med15 PF09606.5 CDI73891.1 - 0.19 9.8 28.4 0.22 9.6 19.7 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal CDK5_activator PF03261.10 CDI73891.1 - 0.27 10.5 16.0 0.34 10.2 11.1 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein Suf PF05843.9 CDI73891.1 - 0.51 10.0 16.0 0.61 9.7 11.1 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) RAP1 PF07218.6 CDI73891.1 - 0.97 7.4 12.1 0.87 7.6 8.4 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DUF4407 PF14362.1 CDI73891.1 - 3.2 6.6 19.0 3.5 6.4 13.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Apt1 PF10351.4 CDI73891.1 - 3.5 6.3 13.7 5.3 5.7 9.5 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain PAT1 PF09770.4 CDI73891.1 - 5.1 5.2 22.1 6.4 4.8 15.3 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SOBP PF15279.1 CDI73891.1 - 5.3 7.3 18.4 6 7.1 12.8 1.0 1 0 0 1 1 1 0 Sine oculis-binding protein Raftlin PF15250.1 CDI73891.1 - 8.3 4.8 14.6 11 4.4 10.1 1.1 1 0 0 1 1 1 0 Raftlin RAB3GAP2_N PF14655.1 CDI73891.1 - 8.5 5.2 13.0 8.3 5.2 8.3 1.5 1 1 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Pollen_allerg_2 PF01620.11 CDI73892.1 - 0.3 11.3 12.4 0.4 10.9 8.6 1.2 1 0 0 1 1 1 0 Ribonuclease (pollen allergen) AMP-binding PF00501.23 CDI73892.1 - 0.33 9.2 2.8 0.37 9.1 2.0 1.1 1 0 0 1 1 1 0 AMP-binding enzyme DUF1510 PF07423.6 CDI73892.1 - 0.84 8.9 15.9 1.1 8.5 11.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) BTV_NS2 PF04514.7 CDI73892.1 - 1.8 7.3 10.1 2.4 6.9 7.0 1.3 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 FAM60A PF15396.1 CDI73892.1 - 2.5 7.8 16.3 3.2 7.4 11.3 1.1 1 0 0 1 1 1 0 Protein Family FAM60A FLO_LFY PF01698.11 CDI73892.1 - 2.5 6.8 13.9 3.2 6.5 9.6 1.3 1 0 0 1 1 1 0 Floricaula / Leafy protein DUF3474 PF11960.3 CDI73892.1 - 3 7.8 11.2 3.1 7.8 7.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF3474) Herpes_DNAp_acc PF04929.7 CDI73892.1 - 3.1 6.6 17.8 3.4 6.5 12.4 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Herpes_TAF50 PF03326.8 CDI73892.1 - 5.3 5.8 27.9 6.3 5.6 19.3 1.1 1 0 0 1 1 1 0 Herpesvirus transcription activation factor (transactivator) Shadoo PF14999.1 CDI73892.1 - 5.3 6.9 9.8 5.4 6.8 5.9 1.6 2 0 0 2 2 2 0 Shadow of prion protein, neuroprotective YfhO PF09586.5 CDI73892.1 - 7.2 4.4 10.9 7.7 4.3 7.5 1.1 1 0 0 1 1 1 0 Bacterial membrane protein YfhO DUF2215 PF10225.4 CDI73892.1 - 7.3 5.9 9.2 8.3 5.7 6.4 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) Serinc PF03348.10 CDI73892.1 - 7.5 5.1 11.9 9.7 4.7 8.3 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) Folate_carrier PF01770.13 CDI73892.1 - 7.6 4.9 6.8 8.6 4.7 4.7 1.3 1 0 0 1 1 1 0 Reduced folate carrier DDHD PF02862.12 CDI73892.1 - 7.6 6.2 14.6 11 5.6 10.1 1.4 1 0 0 1 1 1 0 DDHD domain Med15 PF09606.5 CDI73892.1 - 7.9 4.5 56.0 8.8 4.3 38.8 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal MIP-T3 PF10243.4 CDI73893.1 - 4.2e-06 25.5 39.5 4.2e-06 25.5 27.4 2.2 2 0 0 2 2 2 1 Microtubule-binding protein MIP-T3 UPF0560 PF10577.4 CDI73893.1 - 0.00012 20.4 15.2 0.00012 20.4 10.5 4.7 2 1 2 5 5 5 1 Uncharacterised protein family UPF0560 Utp14 PF04615.8 CDI73893.1 - 0.21 9.7 64.0 0.054 11.6 6.6 2.3 2 0 0 2 2 2 0 Utp14 protein DUF2076 PF09849.4 CDI73895.1 - 0.004 17.2 4.4 0.0051 16.9 3.0 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) E_Pc_C PF06752.7 CDI73895.1 - 0.061 12.8 9.1 0.083 12.3 6.3 1.2 1 0 0 1 1 1 0 Enhancer of Polycomb C-terminus FHIPEP PF00771.15 CDI73895.1 - 0.09 11.0 2.2 0.12 10.6 1.5 1.2 1 0 0 1 1 1 0 FHIPEP family Daxx PF03344.10 CDI73895.1 - 0.13 10.7 29.9 0.15 10.4 20.7 1.0 1 0 0 1 1 1 0 Daxx Family NOA36 PF06524.7 CDI73895.1 - 0.35 10.0 11.3 0.44 9.7 7.9 1.3 1 0 0 1 1 1 0 NOA36 protein Nop14 PF04147.7 CDI73895.1 - 0.36 8.6 25.3 0.53 8.1 17.5 1.2 1 0 0 1 1 1 0 Nop14-like family DUF3138 PF11336.3 CDI73895.1 - 1.1 7.3 8.5 1.1 7.2 5.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) RAB3GAP2_C PF14656.1 CDI73895.1 - 1.3 7.1 8.3 1.3 7.0 5.8 1.1 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit C-terminus CDC45 PF02724.9 CDI73895.1 - 1.3 6.9 18.2 1.7 6.5 12.6 1.2 1 0 0 1 1 1 0 CDC45-like protein PPP4R2 PF09184.6 CDI73895.1 - 1.4 8.4 27.4 1.9 7.9 19.0 1.2 1 0 0 1 1 1 0 PPP4R2 CDC27 PF09507.5 CDI73895.1 - 1.4 8.0 23.8 1.6 7.8 16.5 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 AAA_23 PF13476.1 CDI73895.1 - 1.6 9.0 12.4 2.2 8.5 8.6 1.2 1 0 0 1 1 1 0 AAA domain BTV_NS2 PF04514.7 CDI73895.1 - 1.6 7.5 20.5 1.9 7.3 14.2 1.0 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Sporozoite_P67 PF05642.6 CDI73895.1 - 1.7 6.4 14.8 1.9 6.2 10.3 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DDHD PF02862.12 CDI73895.1 - 2.2 8.0 12.8 3 7.5 8.9 1.3 1 0 0 1 1 1 0 DDHD domain PAT1 PF09770.4 CDI73895.1 - 2.9 5.9 14.4 3.2 5.8 10.0 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 R_equi_Vir PF05526.6 CDI73895.1 - 3.1 7.4 4.6 3.9 7.0 3.2 1.3 1 0 0 1 1 1 0 Rhodococcus equi virulence-associated protein Zip PF02535.17 CDI73895.1 - 3.3 6.6 8.4 3.8 6.4 5.8 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter RRN3 PF05327.6 CDI73895.1 - 3.7 5.5 14.0 4.8 5.1 9.7 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 ADP_ribosyl_GH PF03747.9 CDI73895.1 - 3.9 7.1 8.5 4.3 7.0 5.9 1.1 1 0 0 1 1 1 0 ADP-ribosylglycohydrolase Pilt PF15453.1 CDI73895.1 - 4.1 6.9 19.6 4.6 6.8 13.6 1.0 1 0 0 1 1 1 0 Protein incorporated later into Tight Junctions DUF1510 PF07423.6 CDI73895.1 - 4.1 6.6 26.7 5.1 6.4 18.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) RNase_H2-Ydr279 PF09468.5 CDI73895.1 - 8.2 5.5 8.2 9.8 5.2 5.7 1.1 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) Milton PF12448.3 CDI73895.1 - 9.1 6.4 9.3 12 6.0 6.4 1.2 1 0 0 1 1 1 0 Kinesin associated protein DUF3537 PF12056.3 CDI73895.1 - 9.3 4.8 6.6 11 4.5 4.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3537) DUF2126 PF09899.4 CDI73897.1 - 0.085 10.8 6.2 0.12 10.3 4.3 1.2 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) FLO_LFY PF01698.11 CDI73897.1 - 0.46 9.2 6.8 1 8.1 4.7 1.5 1 0 0 1 1 1 0 Floricaula / Leafy protein FimP PF09766.4 CDI73897.1 - 0.66 8.9 17.8 0.96 8.4 12.3 1.1 1 0 0 1 1 1 0 Fms-interacting protein Serinc PF03348.10 CDI73897.1 - 0.99 8.0 6.6 1.8 7.2 4.6 1.4 1 0 0 1 1 1 0 Serine incorporator (Serinc) DDHD PF02862.12 CDI73897.1 - 1 9.1 12.3 0.3 10.8 4.2 2.2 2 0 0 2 2 2 0 DDHD domain UPF0560 PF10577.4 CDI73897.1 - 5.3 5.1 21.3 9.4 4.3 14.8 1.3 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Glyco_transf_15 PF01793.11 CDI73897.1 - 6.1 5.6 7.4 11 4.8 5.1 1.3 1 0 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase RR_TM4-6 PF06459.7 CDI73897.1 - 6.3 6.5 17.5 0.11 12.3 6.9 1.8 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Hid1 PF12722.2 CDI73897.1 - 6.8 4.2 7.6 10 3.6 5.3 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein OATP PF03137.15 CDI73897.1 - 8.7 4.2 5.8 14 3.6 4.0 1.2 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family DUF1299 PF06975.6 CDI73898.1 - 0.53 10.1 0.2 0.53 10.1 0.2 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF1299) Suf PF05843.9 CDI73898.1 - 7.6 6.1 9.9 7.7 6.1 6.9 1.0 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) SprA-related PF12118.3 CDI73899.1 - 0.048 12.9 12.7 0.052 12.8 8.8 1.2 1 0 0 1 1 1 0 SprA-related family Suf PF05843.9 CDI73899.1 - 0.11 12.1 8.2 0.12 12.1 5.7 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) RR_TM4-6 PF06459.7 CDI73899.1 - 0.12 12.2 7.7 0.13 12.1 5.3 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Borrelia_P83 PF05262.6 CDI73899.1 - 0.4 8.9 8.0 0.45 8.7 5.5 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Apc13p PF05839.6 CDI73899.1 - 0.66 9.9 5.7 1.1 9.3 4.0 1.3 1 0 0 1 1 1 0 Apc13p protein Sec62 PF03839.11 CDI73899.1 - 0.68 9.3 4.9 0.9 8.9 3.4 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 DDHD PF02862.12 CDI73899.1 - 0.78 9.4 5.4 0.73 9.5 3.8 1.2 1 0 0 1 1 1 0 DDHD domain Cellulose_synt PF03552.9 CDI73899.1 - 0.83 7.8 2.3 0.89 7.7 1.6 1.0 1 0 0 1 1 1 0 Cellulose synthase DUF3682 PF12446.3 CDI73899.1 - 1.6 9.0 13.9 2.6 8.3 9.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) DUF1675 PF07897.6 CDI73899.1 - 1.8 8.3 9.7 2.3 8.0 6.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) DUF2058 PF09831.4 CDI73899.1 - 2.2 8.1 16.4 3.4 7.5 11.3 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2058) OmpH PF03938.9 CDI73899.1 - 2.2 8.1 15.8 3 7.7 11.0 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) UPF0560 PF10577.4 CDI73899.1 - 2.8 6.0 9.8 3.6 5.7 6.8 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Pex14_N PF04695.8 CDI73899.1 - 3.3 7.7 10.7 5.8 6.9 7.4 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region FAM176 PF14851.1 CDI73899.1 - 4.5 6.9 5.9 6.9 6.3 4.1 1.3 1 0 0 1 1 1 0 FAM176 family BAF1_ABF1 PF04684.8 CDI73899.1 - 6.7 5.4 14.0 8.5 5.0 9.7 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Band_3_cyto PF07565.8 CDI73899.1 - 9.4 5.6 9.2 12 5.2 6.4 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain DUF755 PF05501.6 CDI73901.1 - 0.005 16.8 23.9 0.005 16.8 16.6 8.7 6 3 1 7 7 7 3 Domain of unknown function (DUF755) Plug_translocon PF10559.4 CDI73903.1 - 4.9e-19 67.5 0.1 8e-19 66.8 0.0 1.4 1 0 0 1 1 1 1 Plug domain of Sec61p SecY PF00344.15 CDI73903.1 - 7e-18 64.6 1.1 1e-17 64.0 0.8 1.3 1 0 0 1 1 1 1 SecY translocase RRM_1 PF00076.17 CDI73904.1 - 3.3e-31 106.7 0.0 7.1e-12 44.7 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CDI73904.1 - 2.1e-19 69.2 0.0 7.5e-07 29.0 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CDI73904.1 - 3.4e-10 39.6 0.0 0.00083 19.1 0.0 3.0 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 CDI73904.1 - 0.001 18.7 0.0 1.6 8.5 0.0 3.0 3 0 0 3 3 3 2 Limkain b1 RRM_3 PF08777.6 CDI73904.1 - 0.0036 17.1 0.0 11 5.9 0.0 3.2 3 0 0 3 3 3 1 RNA binding motif WD40 PF00400.27 CDI73905.1 - 0.016 15.0 0.0 0.13 12.1 0.0 2.6 2 0 0 2 2 2 0 WD domain, G-beta repeat Guanylate_cyc PF00211.15 CDI73907.1 - 1e-18 67.3 0.1 2.8e-09 36.6 0.0 2.3 2 0 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain Med15 PF09606.5 CDI73908.1 - 0.00011 20.5 78.5 0.00011 20.5 54.4 10.8 6 4 2 9 9 9 2 ARC105 or Med15 subunit of Mediator complex non-fungal SR-25 PF10500.4 CDI73908.1 - 0.0039 16.7 22.8 0.0039 16.7 15.8 16.2 11 4 3 15 15 15 2 Nuclear RNA-splicing-associated protein Tmemb_185A PF10269.4 CDI73908.1 - 4.9 6.6 8.4 55 3.2 0.4 4.5 3 0 0 3 3 3 0 Transmembrane Fragile-X-F protein C2 PF00168.25 CDI73909.1 - 6.6e-16 57.9 0.1 1.3e-09 37.7 0.0 3.9 4 0 0 4 4 4 3 C2 domain PCI PF01399.22 CDI73910.1 - 1e-11 45.0 0.2 1.9e-11 44.2 0.1 1.4 1 0 0 1 1 1 1 PCI domain TPR_2 PF07719.12 CDI73910.1 - 0.017 14.9 0.1 0.46 10.5 0.0 2.9 2 1 0 2 2 2 0 Tetratricopeptide repeat Nucleoporin_FG PF13634.1 CDI73912.1 - 4.1e-17 62.4 93.7 5.2e-10 39.5 29.7 12.5 7 4 4 11 11 11 4 Nucleoporin FG repeat region Nucleoporin2 PF04096.9 CDI73912.1 - 0.011 15.6 0.0 0.011 15.6 0.0 3.8 4 1 0 4 4 4 0 Nucleoporin autopeptidase YjgP_YjgQ PF03739.9 CDI73912.1 - 0.092 11.4 0.0 0.092 11.4 0.0 3.5 3 1 0 3 3 3 0 Predicted permease YjgP/YjgQ family DUF1712 PF08217.6 CDI73913.1 - 0.22 9.7 19.5 0.0079 14.4 8.9 1.8 2 0 0 2 2 2 0 Fungal domain of unknown function (DUF1712) RAP1 PF07218.6 CDI73913.1 - 1.6 6.7 10.1 2 6.4 7.0 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Na_trans_assoc PF06512.8 CDI73913.1 - 3.3 7.6 19.8 8.4 6.2 10.4 2.4 2 0 0 2 2 2 0 Sodium ion transport-associated DUF1183 PF06682.7 CDI73913.1 - 3.4 7.2 32.4 3.6 7.1 16.3 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1183) Shadoo PF14999.1 CDI73913.1 - 4.7 7.0 31.9 0.08 12.8 6.2 3.3 2 1 1 3 3 3 0 Shadow of prion protein, neuroprotective Pap_E4 PF02711.9 CDI73914.1 - 0.026 15.3 0.6 0.026 15.3 0.4 8.2 7 1 3 10 10 10 0 E4 protein HTH_38 PF13936.1 CDI73915.1 - 0.0026 17.2 0.2 0.0026 17.2 0.2 2.0 2 0 0 2 2 1 1 Helix-turn-helix domain DUF1510 PF07423.6 CDI73915.1 - 0.0043 16.4 15.3 0.0043 16.4 10.6 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1510) GerE PF00196.14 CDI73915.1 - 0.014 14.7 0.0 0.025 13.9 0.0 1.3 1 0 0 1 1 1 0 Bacterial regulatory proteins, luxR family Rrf2 PF02082.15 CDI73915.1 - 0.16 12.0 0.1 0.16 12.0 0.0 2.3 3 0 0 3 3 3 0 Transcriptional regulator SpoIIIAH PF12685.2 CDI73915.1 - 0.17 11.3 27.0 0.08 12.4 9.2 2.3 2 0 0 2 2 2 0 SpoIIIAH-like protein DUF3807 PF12720.2 CDI73915.1 - 0.25 11.5 37.2 0.48 10.5 12.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3807) HTH_23 PF13384.1 CDI73915.1 - 0.28 10.9 2.7 0.32 10.7 0.1 2.4 2 0 0 2 2 2 0 Homeodomain-like domain PLRV_ORF5 PF01690.12 CDI73915.1 - 0.69 8.9 28.9 0.9 8.6 20.0 1.2 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Spore_coat_CotO PF14153.1 CDI73915.1 - 0.91 8.9 44.8 2 7.8 18.1 2.2 2 0 0 2 2 2 0 Spore coat protein CotO FYDLN_acid PF09538.5 CDI73915.1 - 1.6 9.3 18.2 3.6 8.2 5.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) TRAP_alpha PF03896.11 CDI73915.1 - 1.7 7.5 12.5 1.1 8.2 3.9 2.1 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit Pox_Ag35 PF03286.9 CDI73915.1 - 3.5 7.1 22.2 5.1 6.5 1.3 2.1 2 0 0 2 2 2 0 Pox virus Ag35 surface protein Rtf2 PF04641.7 CDI73915.1 - 3.6 6.7 31.8 3.6 6.7 3.9 2.1 2 0 0 2 2 2 0 Rtf2 RING-finger Ycf1 PF05758.7 CDI73915.1 - 4.9 4.7 32.4 0.41 8.2 11.6 2.0 2 0 0 2 2 2 0 Ycf1 DUF4175 PF13779.1 CDI73915.1 - 4.9 4.7 88.6 1.3 6.6 18.7 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4175) Herpes_DNAp_acc PF04929.7 CDI73915.1 - 6.3 5.6 27.2 1.7 7.4 9.3 2.1 2 0 0 2 2 2 0 Herpes DNA replication accessory factor PIH1 PF08190.7 CDI73915.1 - 7.3 5.9 40.6 6.4 6.1 15.1 2.1 2 0 0 2 2 2 0 pre-RNA processing PIH1/Nop17 Parvo_coat PF00740.13 CDI73915.1 - 9.7 5.0 32.6 12 4.6 22.6 1.2 1 0 0 1 1 1 0 Parvovirus coat protein VP2 IncA PF04156.9 CDI73916.1 - 4.6e-05 23.1 29.0 5.4e-05 22.8 20.1 1.1 1 0 0 1 1 1 1 IncA protein Ctr PF04145.10 CDI73916.1 - 0.0071 16.4 10.7 0.0096 15.9 7.4 1.2 1 0 0 1 1 1 1 Ctr copper transporter family U79_P34 PF03064.11 CDI73916.1 - 0.063 12.7 18.0 0.069 12.6 12.5 1.0 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Shadoo PF14999.1 CDI73916.1 - 0.074 12.9 2.4 0.093 12.5 1.7 1.2 1 0 0 1 1 1 0 Shadow of prion protein, neuroprotective Ureide_permease PF07168.6 CDI73916.1 - 0.16 10.5 3.5 0.18 10.4 2.4 1.1 1 0 0 1 1 1 0 Ureide permease DUF1510 PF07423.6 CDI73916.1 - 0.17 11.2 23.5 0.19 11.0 16.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) PMSI1 PF15322.1 CDI73916.1 - 0.29 10.1 19.3 0.31 10.0 13.4 1.0 1 0 0 1 1 1 0 Protein missing in infertile sperm 1, putative DUF4446 PF14584.1 CDI73916.1 - 0.31 10.8 12.7 0.36 10.6 8.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) Peptidase_S49_N PF08496.5 CDI73916.1 - 0.38 10.5 19.4 0.48 10.2 13.5 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal HemX PF04375.9 CDI73916.1 - 0.4 9.2 44.6 0.43 9.1 30.9 1.0 1 0 0 1 1 1 0 HemX Pal1 PF08316.6 CDI73916.1 - 0.5 10.8 14.6 0.53 10.7 10.1 1.1 1 0 0 1 1 1 0 Pal1 cell morphology protein Peptidase_S15 PF02129.13 CDI73916.1 - 0.75 9.1 20.2 0.85 8.9 14.0 1.1 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) DDHD PF02862.12 CDI73916.1 - 0.89 9.3 21.2 0.9 9.2 14.7 1.1 1 0 0 1 1 1 0 DDHD domain Herpes_glycop PF01528.11 CDI73916.1 - 1.1 7.9 8.1 1.3 7.6 5.6 1.2 1 0 0 1 1 1 0 Herpesvirus glycoprotein M Serinc PF03348.10 CDI73916.1 - 1.2 7.7 19.2 1.3 7.6 13.3 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) DHHW PF14286.1 CDI73916.1 - 1.4 8.1 19.0 1.5 8.0 13.2 1.0 1 0 0 1 1 1 0 DHHW protein DUF2217 PF10265.4 CDI73916.1 - 1.5 7.5 13.0 1.6 7.4 9.0 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) SID-1_RNA_chan PF13965.1 CDI73916.1 - 2.1 6.3 11.7 2.2 6.3 8.1 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 PPP4R2 PF09184.6 CDI73916.1 - 2.2 7.7 17.5 2.2 7.7 12.1 1.1 1 0 0 1 1 1 0 PPP4R2 PCEMA1 PF07418.6 CDI73916.1 - 2.3 7.5 10.3 2.2 7.5 7.2 1.1 1 0 0 1 1 1 0 Acidic phosphoprotein precursor PCEMA1 FAM60A PF15396.1 CDI73916.1 - 2.3 7.9 18.9 2.4 7.8 13.1 1.0 1 0 0 1 1 1 0 Protein Family FAM60A FMN_dh PF01070.13 CDI73916.1 - 2.5 6.8 13.6 2.8 6.7 9.4 1.1 1 0 0 1 1 1 0 FMN-dependent dehydrogenase CDC45 PF02724.9 CDI73916.1 - 2.8 5.8 20.8 2.9 5.7 14.4 1.1 1 0 0 1 1 1 0 CDC45-like protein FLO_LFY PF01698.11 CDI73916.1 - 3 6.6 23.8 3.2 6.5 16.5 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein DUF4045 PF13254.1 CDI73916.1 - 3.1 6.9 20.3 3.1 6.9 14.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) FNIP_N PF14636.1 CDI73916.1 - 3.1 8.2 21.7 3.7 8.0 15.0 1.3 1 0 0 1 1 1 0 Folliculin-interacting protein N-terminus Chorismate_synt PF01264.16 CDI73916.1 - 3.2 6.1 11.1 4.2 5.7 7.7 1.2 1 0 0 1 1 1 0 Chorismate synthase DUF3357 PF11837.3 CDI73916.1 - 3.2 7.6 12.1 2.3e+02 1.6 8.4 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF3357) Exonuc_VII_L PF02601.10 CDI73916.1 - 3.8 6.6 23.4 4.3 6.4 16.2 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit eIF3_subunit PF08597.5 CDI73916.1 - 4.4 6.8 24.4 4.5 6.7 16.9 1.3 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit Raftlin PF15250.1 CDI73916.1 - 4.6 5.6 22.5 4.7 5.6 15.6 1.0 1 0 0 1 1 1 0 Raftlin Folate_carrier PF01770.13 CDI73916.1 - 4.7 5.6 13.7 5.2 5.4 9.5 1.1 1 0 0 1 1 1 0 Reduced folate carrier DUF2215 PF10225.4 CDI73916.1 - 5.6 6.3 13.3 6.1 6.2 9.3 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) RR_TM4-6 PF06459.7 CDI73916.1 - 5.9 6.7 24.0 5.8 6.7 16.6 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 GAGA_bind PF06217.7 CDI73916.1 - 6.2 6.6 21.4 6.2 6.6 14.9 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family NARP1 PF12569.3 CDI73916.1 - 6.8 5.3 25.2 7.1 5.2 17.5 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 FHIPEP PF00771.15 CDI73916.1 - 7 4.8 21.6 15 3.7 14.9 1.5 1 1 0 1 1 1 0 FHIPEP family DUF822 PF05687.8 CDI73916.1 - 7.2 6.9 16.8 8.2 6.7 11.6 1.2 1 0 0 1 1 1 0 Plant protein of unknown function (DUF822) Peptidase_U57 PF05582.7 CDI73916.1 - 7.3 5.4 18.0 7.7 5.3 12.5 1.1 1 0 0 1 1 1 0 YabG peptidase U57 SAGA-Tad1 PF12767.2 CDI73916.1 - 7.6 6.1 27.2 7.6 6.1 18.9 1.1 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit Tim54 PF11711.3 CDI73916.1 - 9.4 4.7 17.1 9.5 4.6 11.8 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 RNA_pol_Rpb1_5 PF04998.12 CDI73916.1 - 9.6 5.3 14.4 9.5 5.3 10.0 1.0 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 Kelch_1 PF01344.20 CDI73917.1 - 4.9e-16 58.0 0.0 1.5e-08 34.0 0.0 2.6 2 0 0 2 2 2 2 Kelch motif Kelch_4 PF13418.1 CDI73917.1 - 6.1e-16 57.9 0.1 3.3e-07 29.9 0.0 2.7 2 0 0 2 2 2 2 Galactose oxidase, central domain Kelch_2 PF07646.10 CDI73917.1 - 2.6e-13 49.1 0.1 3.6e-07 29.6 0.0 3.0 2 0 0 2 2 2 2 Kelch motif BTB PF00651.26 CDI73917.1 - 3.4e-13 49.5 0.0 6.9e-13 48.5 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain Kelch_3 PF13415.1 CDI73917.1 - 4.5e-12 45.7 8.8 2.7e-06 27.3 0.0 5.2 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_5 PF13854.1 CDI73917.1 - 7.3e-11 41.7 0.0 4.1e-05 23.4 0.0 3.0 3 0 0 3 3 3 2 Kelch motif Kelch_6 PF13964.1 CDI73917.1 - 4.5e-10 39.2 0.0 0.0016 18.4 0.0 3.0 2 0 0 2 2 2 2 Kelch motif DUF2981 PF11200.3 CDI73917.1 - 2.1 7.3 4.5 3.4 6.6 3.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) Cript PF10235.4 CDI73918.1 - 6.1e-16 58.5 7.3 6.1e-16 58.5 5.0 1.7 1 1 0 1 1 1 1 Microtubule-associated protein CRIPT C6_DPF PF10170.4 CDI73918.1 - 0.063 13.3 4.2 0.089 12.8 2.9 1.6 1 1 0 1 1 1 0 Cysteine-rich domain DZR PF12773.2 CDI73918.1 - 0.16 11.7 9.8 0.13 12.1 3.3 2.3 1 1 1 2 2 2 0 Double zinc ribbon DiS_P_DiS PF06750.8 CDI73918.1 - 1.6 8.5 7.2 1.1 9.0 2.4 2.5 1 1 1 2 2 2 0 Bacterial Peptidase A24 N-terminal domain Sar8_2 PF03058.9 CDI73918.1 - 1.7 9.0 13.1 24 5.3 9.1 2.2 1 1 0 1 1 1 0 Sar8.2 family C1_1 PF00130.17 CDI73918.1 - 3.6 7.3 12.2 1.4e+02 2.2 0.7 2.9 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF1272 PF06906.6 CDI73918.1 - 6 6.8 8.3 11 5.9 3.1 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1272) Utp14 PF04615.8 CDI73919.1 - 0.26 9.4 86.9 0.36 8.9 60.3 1.1 1 0 0 1 1 1 0 Utp14 protein Neur_chan_memb PF02932.11 CDI73921.1 - 2.9 7.7 4.6 6.8 6.5 3.2 1.5 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region adh_short PF00106.20 CDI73924.1 - 5.5e-24 84.9 3.0 5.5e-11 42.6 1.8 2.4 1 1 1 2 2 2 2 short chain dehydrogenase KR PF08659.5 CDI73924.1 - 7.9e-11 41.9 1.0 5.5e-08 32.6 0.7 2.2 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 CDI73924.1 - 1.3e-07 31.6 0.1 2.1e-07 30.9 0.1 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Eno-Rase_NADH_b PF12242.3 CDI73924.1 - 0.0054 16.5 0.2 0.015 15.0 0.2 1.8 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF1776 PF08643.5 CDI73924.1 - 0.0085 15.2 0.0 0.014 14.5 0.0 1.3 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.1 CDI73924.1 - 0.019 14.9 0.7 0.036 14.0 0.3 1.7 2 0 0 2 2 2 0 NADH(P)-binding DFP PF04127.10 CDI73924.1 - 0.028 14.0 0.9 0.39 10.3 0.3 2.5 2 2 1 3 3 3 0 DNA / pantothenate metabolism flavoprotein Polysacc_synt_2 PF02719.10 CDI73924.1 - 0.074 11.9 0.0 0.13 11.1 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Epimerase PF01370.16 CDI73924.1 - 0.099 12.0 0.1 0.68 9.3 0.0 2.0 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family LRR_4 PF12799.2 CDI73925.1 - 9.5e-13 47.4 0.2 0.0021 17.6 0.0 5.6 4 1 3 7 7 7 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CDI73925.1 - 6.5e-12 45.0 2.1 3.4e-07 29.9 0.0 3.8 3 1 0 3 3 3 2 Leucine rich repeat LRR_6 PF13516.1 CDI73925.1 - 2.2e-05 24.0 1.3 25 5.3 0.0 6.7 8 0 0 8 8 8 0 Leucine Rich repeat LRR_7 PF13504.1 CDI73925.1 - 6e-05 22.6 6.1 38 5.1 0.0 7.9 7 1 0 7 7 7 0 Leucine rich repeat LRR_1 PF00560.28 CDI73925.1 - 7.5e-05 22.2 5.2 12 6.3 0.0 7.0 6 3 1 7 7 7 1 Leucine Rich Repeat DUF4557 PF15101.1 CDI73925.1 - 0.1 12.3 2.7 0.17 11.7 1.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) DUF3682 PF12446.3 CDI73925.1 - 8.6 6.6 8.1 15 5.9 5.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) DUF3639 PF12341.3 CDI73926.1 - 2.3e-05 24.3 0.9 4.8e-05 23.2 0.6 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3639) Acid_PPase PF12689.2 CDI73927.1 - 0.018 14.6 0.0 0.031 13.9 0.0 1.3 1 0 0 1 1 1 0 Acid Phosphatase HAD_2 PF13419.1 CDI73927.1 - 0.055 13.6 0.0 0.6 10.3 0.0 2.1 2 1 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Glyco_trans_4_4 PF13579.1 CDI73927.1 - 0.087 12.9 0.3 0.13 12.4 0.2 1.2 1 0 0 1 1 1 0 Glycosyl transferase 4-like domain Kri1_C PF12936.2 CDI73927.1 - 0.1 12.5 0.0 0.14 12.0 0.0 1.2 1 0 0 1 1 1 0 KRI1-like family C-terminal DUF4448 PF14610.1 CDI73928.1 - 0.048 13.1 2.1 0.93 8.9 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4448) PAT1 PF09770.4 CDI73928.1 - 0.17 10.0 63.5 0.25 9.5 44.0 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Rifin_STEVOR PF02009.11 CDI73928.1 - 0.62 9.6 14.2 0.12 11.9 0.2 2.2 2 0 0 2 2 2 0 Rifin/stevor family DUF912 PF06024.7 CDI73928.1 - 1.7 8.7 0.0 1.7 8.7 0.0 4.2 4 2 0 4 4 4 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Herpes_DNAp_acc PF04929.7 CDI73929.1 - 0.0056 15.7 10.7 0.0065 15.4 7.4 1.0 1 0 0 1 1 1 1 Herpes DNA replication accessory factor RskA PF10099.4 CDI73929.1 - 0.0084 15.8 4.5 0.011 15.5 3.1 1.3 1 0 0 1 1 1 1 Anti-sigma-K factor rskA Mem_trans PF03547.13 CDI73929.1 - 0.023 13.0 5.2 0.026 12.8 3.6 1.0 1 0 0 1 1 1 0 Membrane transport protein DUF3260 PF11658.3 CDI73929.1 - 0.027 12.6 8.7 0.028 12.5 6.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3260) YfhO PF09586.5 CDI73929.1 - 0.031 12.3 9.1 0.033 12.2 6.3 1.0 1 0 0 1 1 1 0 Bacterial membrane protein YfhO ABC2_membrane_2 PF12679.2 CDI73929.1 - 0.1 11.4 2.8 0.12 11.2 1.9 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein Topoisom_I_N PF02919.10 CDI73929.1 - 0.1 11.8 4.3 0.13 11.5 3.0 1.2 1 0 0 1 1 1 0 Eukaryotic DNA topoisomerase I, DNA binding fragment Med15 PF09606.5 CDI73929.1 - 0.11 10.6 39.2 0.13 10.4 27.1 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Sex_peptide PF08138.6 CDI73929.1 - 0.21 11.4 0.8 0.67 9.8 0.6 2.0 1 0 0 1 1 1 0 Sex peptide (SP) family DDHD PF02862.12 CDI73929.1 - 0.21 11.3 8.5 0.24 11.1 5.9 1.2 1 0 0 1 1 1 0 DDHD domain UPF0565 PF10561.4 CDI73929.1 - 0.33 9.7 7.0 0.38 9.6 4.9 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0565 DUF3357 PF11837.3 CDI73929.1 - 0.33 10.8 4.5 0.17 11.7 1.3 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF3357) DUF506 PF04720.7 CDI73929.1 - 0.39 10.3 8.7 0.45 10.1 6.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF506) GRP PF07172.6 CDI73929.1 - 0.55 10.7 6.0 0.22 12.0 2.0 1.8 1 1 1 2 2 2 0 Glycine rich protein family Pex16 PF08610.5 CDI73929.1 - 0.56 9.1 18.8 0.67 8.8 13.1 1.1 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) ALG3 PF05208.8 CDI73929.1 - 0.79 8.8 5.9 0.92 8.6 4.1 1.1 1 0 0 1 1 1 0 ALG3 protein Glyco_transf_6 PF03414.8 CDI73929.1 - 1.1 7.7 6.8 1.4 7.3 4.7 1.2 1 0 0 1 1 1 0 Glycosyltransferase family 6 DUF1510 PF07423.6 CDI73929.1 - 1.2 8.5 15.0 1.8 7.8 10.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1510) Na_trans_assoc PF06512.8 CDI73929.1 - 1.2 9.0 9.0 1.6 8.6 6.2 1.1 1 0 0 1 1 1 0 Sodium ion transport-associated OAD_gamma PF04277.8 CDI73929.1 - 1.6 9.1 7.4 0.55 10.6 2.5 2.1 2 1 0 2 2 1 0 Oxaloacetate decarboxylase, gamma chain Peptidase_S15 PF02129.13 CDI73929.1 - 2.3 7.5 7.7 2.3 7.5 5.3 1.2 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) DUF4437 PF14499.1 CDI73929.1 - 2.3 7.0 7.6 3.1 6.6 5.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4437) FliP PF00813.15 CDI73929.1 - 3 7.4 7.6 3.6 7.2 5.2 1.1 1 0 0 1 1 1 0 FliP family Neur_chan_memb PF02932.11 CDI73929.1 - 3.9 7.2 7.1 4.6 7.0 4.9 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Peptidase_U57 PF05582.7 CDI73929.1 - 4.7 6.1 8.9 5.4 5.8 6.1 1.2 1 0 0 1 1 1 0 YabG peptidase U57 DUF2309 PF10070.4 CDI73929.1 - 4.8 5.1 18.0 5.6 4.9 12.5 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2309) TFIIA PF03153.8 CDI73929.1 - 6.6 6.5 24.0 7.2 6.4 16.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Stig1 PF04885.8 CDI73929.1 - 7.5 6.7 6.7 11 6.1 4.7 1.4 1 1 0 1 1 1 0 Stigma-specific protein, Stig1 ETRAMP PF09716.5 CDI73929.1 - 8.9 6.3 6.5 1.2 9.1 0.4 2.3 3 0 0 3 3 3 0 Malarial early transcribed membrane protein (ETRAMP) Ctr PF04145.10 CDI73929.1 - 9.4 6.2 12.6 19 5.3 8.8 1.6 1 1 0 1 1 1 0 Ctr copper transporter family PH_4 PF15404.1 CDI73929.1 - 9.6 5.6 14.2 3.5 7.1 8.1 1.5 1 1 0 1 1 1 0 Pleckstrin homology domain Med15 PF09606.5 CDI73930.1 - 0.5 8.5 41.7 0.71 8.0 28.9 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal CD20 PF04103.10 CDI73930.1 - 0.51 10.2 5.1 3.2 7.6 1.3 2.1 2 0 0 2 2 2 0 CD20-like family NMDAR2_C PF10565.4 CDI73930.1 - 0.98 8.0 11.3 1.1 7.7 7.8 1.1 1 0 0 1 1 1 0 N-methyl D-aspartate receptor 2B3 C-terminus DUF3801 PF12687.2 CDI73930.1 - 4 6.9 21.5 5.5 6.4 14.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3801) Hamartin PF04388.7 CDI73930.1 - 5.5 5.5 15.1 8 5.0 10.4 1.2 1 0 0 1 1 1 0 Hamartin protein Utp14 PF04615.8 CDI73931.1 - 0.046 11.8 31.2 0.074 11.2 21.6 1.3 1 0 0 1 1 1 0 Utp14 protein FA_desaturase PF00487.19 CDI73931.1 - 0.56 9.6 4.7 0.17 11.3 0.2 2.3 1 1 0 2 2 2 0 Fatty acid desaturase XAP5 PF04921.9 CDI73931.1 - 1.1 8.7 22.6 0.35 10.3 9.9 2.2 2 0 0 2 2 2 0 XAP5, circadian clock regulator HCO3_cotransp PF00955.16 CDI73932.1 - 0.0045 15.7 1.0 0.0046 15.6 0.7 1.1 1 0 0 1 1 1 1 HCO3- transporter family Raftlin PF15250.1 CDI73932.1 - 0.0079 14.7 12.5 0.0094 14.5 8.7 1.0 1 0 0 1 1 1 1 Raftlin Phage_hub_GP28 PF11110.3 CDI73932.1 - 0.19 11.4 1.1 0.21 11.2 0.4 1.4 1 1 0 1 1 1 0 Baseplate hub distal subunit NPR3 PF03666.8 CDI73932.1 - 0.25 9.8 15.4 0.3 9.5 10.6 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Presenilin PF01080.12 CDI73932.1 - 0.26 10.0 9.6 0.31 9.8 6.7 1.1 1 0 0 1 1 1 0 Presenilin FAM60A PF15396.1 CDI73932.1 - 0.31 10.7 12.8 0.41 10.3 8.9 1.2 1 0 0 1 1 1 0 Protein Family FAM60A Zip PF02535.17 CDI73932.1 - 0.51 9.3 16.3 0.79 8.6 11.3 1.5 1 1 0 1 1 1 0 ZIP Zinc transporter SPX PF03105.14 CDI73932.1 - 0.71 9.5 13.9 0.88 9.2 9.7 1.2 1 0 0 1 1 1 0 SPX domain SOBP PF15279.1 CDI73932.1 - 0.77 10.0 16.6 1.1 9.6 11.5 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein SAGA-Tad1 PF12767.2 CDI73932.1 - 0.85 9.2 18.7 1.2 8.7 13.0 1.2 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit SID-1_RNA_chan PF13965.1 CDI73932.1 - 1.1 7.3 6.2 1.2 7.2 4.3 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Ctr PF04145.10 CDI73932.1 - 1.3 9.1 15.8 0.038 14.0 5.4 1.9 1 1 1 2 2 2 0 Ctr copper transporter family Ribosomal_60s PF00428.14 CDI73932.1 - 1.6 9.1 16.7 2.8 8.4 11.6 1.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein Shadoo PF14999.1 CDI73932.1 - 1.7 8.5 7.3 2.1 8.1 5.1 1.2 1 0 0 1 1 1 0 Shadow of prion protein, neuroprotective Pollen_allerg_2 PF01620.11 CDI73932.1 - 1.8 8.8 9.5 2 8.7 6.6 1.2 1 0 0 1 1 1 0 Ribonuclease (pollen allergen) DUF912 PF06024.7 CDI73932.1 - 2 8.5 17.5 52 3.9 12.1 2.7 1 1 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) LMBR1 PF04791.11 CDI73932.1 - 2 6.8 9.0 2.1 6.8 6.3 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Ycf1 PF05758.7 CDI73932.1 - 3.4 5.2 15.8 4.6 4.8 11.0 1.2 1 0 0 1 1 1 0 Ycf1 Ndc1_Nup PF09531.5 CDI73932.1 - 4.3 5.6 13.4 4.8 5.4 9.3 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF3306 PF11748.3 CDI73932.1 - 4.5 7.9 21.4 0.56 10.8 6.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3306) Kei1 PF08552.6 CDI73932.1 - 4.8 6.8 19.5 0.019 14.6 4.9 2.0 1 1 1 2 2 2 0 Inositolphosphorylceramide synthase subunit Kei1 Hid1 PF12722.2 CDI73932.1 - 6.1 4.3 19.1 7.3 4.1 13.2 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein MDFI PF15316.1 CDI73932.1 - 6.3 6.7 10.5 8 6.4 7.3 1.2 1 0 0 1 1 1 0 MyoD family inhibitor GPCR_chapero_1 PF11904.3 CDI73932.1 - 6.5 5.8 16.1 8.2 5.4 11.2 1.1 1 0 0 1 1 1 0 GPCR-chaperone DUF4045 PF13254.1 CDI73932.1 - 9.8 5.3 17.3 12 5.0 12.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Nuc_recep-AF1 PF11825.3 CDI73933.1 - 0.0054 16.6 4.0 0.0088 15.9 2.8 1.3 1 0 0 1 1 1 1 Nuclear/hormone receptor activator site AF-1 FAM60A PF15396.1 CDI73933.1 - 0.029 14.1 4.3 0.041 13.6 3.0 1.2 1 0 0 1 1 1 0 Protein Family FAM60A PAT1 PF09770.4 CDI73933.1 - 0.032 12.4 33.4 0.035 12.3 23.1 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 CDC45 PF02724.9 CDI73933.1 - 0.12 10.3 2.0 0.15 10.0 1.4 1.2 1 0 0 1 1 1 0 CDC45-like protein Neur_chan_memb PF02932.11 CDI73933.1 - 0.16 11.8 5.5 0.19 11.6 3.3 1.4 1 1 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Ufd2P_core PF10408.4 CDI73933.1 - 0.27 9.4 4.5 0.36 9.0 3.1 1.2 1 0 0 1 1 1 0 Ubiquitin elongating factor core eIF-3_zeta PF05091.7 CDI73933.1 - 0.33 9.5 6.3 0.39 9.2 4.3 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) SPX PF03105.14 CDI73933.1 - 0.35 10.6 7.2 0.44 10.2 5.0 1.2 1 0 0 1 1 1 0 SPX domain TAFII55_N PF04658.8 CDI73933.1 - 0.46 9.9 3.3 0.27 10.7 0.3 1.8 2 0 0 2 2 2 0 TAFII55 protein conserved region AAA_23 PF13476.1 CDI73933.1 - 0.64 10.3 8.6 1.2 9.4 6.0 1.4 1 0 0 1 1 1 0 AAA domain 60KD_IMP PF02096.15 CDI73933.1 - 0.71 9.4 12.3 0.4 10.3 0.3 2.1 2 0 0 2 2 2 0 60Kd inner membrane protein Med15 PF09606.5 CDI73933.1 - 0.85 7.7 37.4 0.93 7.6 26.0 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Kei1 PF08552.6 CDI73933.1 - 1.1 8.9 4.4 1.9 8.1 2.9 1.5 1 1 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 TFIIA PF03153.8 CDI73933.1 - 2.2 8.0 20.9 3.7 7.3 14.5 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit MDFI PF15316.1 CDI73933.1 - 2.5 8.0 6.5 0.85 9.5 2.9 1.3 2 0 0 2 2 1 0 MyoD family inhibitor UPF0233 PF06781.7 CDI73933.1 - 3.2 7.4 5.1 21 4.8 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0233) Presenilin PF01080.12 CDI73933.1 - 4 6.1 5.4 4.5 5.9 3.8 1.1 1 0 0 1 1 1 0 Presenilin Pex16 PF08610.5 CDI73933.1 - 4 6.3 16.0 5.9 5.7 11.1 1.2 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) DUF912 PF06024.7 CDI73933.1 - 4.1 7.4 7.6 4.2 7.4 0.1 2.3 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Hid1 PF12722.2 CDI73933.1 - 7.2 4.1 8.6 7.4 4.1 5.9 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF4519 PF15012.1 CDI73933.1 - 7.3 6.5 7.1 24 4.9 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4519) Myf5 PF12232.3 CDI73933.1 - 7.9 7.1 9.5 1.2 9.8 2.4 2.2 1 1 1 2 2 2 0 Myogenic determination factor 5 Baculo_PP31 PF05311.6 CDI73933.1 - 8.6 5.5 9.6 14 4.8 6.7 1.3 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) BRF1 PF07741.8 CDI73933.1 - 9.9 6.4 12.3 1.2 9.3 1.6 2.3 2 1 0 2 2 2 0 Brf1-like TBP-binding domain DUF3801 PF12687.2 CDI73934.1 - 0.0015 18.1 10.3 0.15 11.6 0.0 3.7 3 0 0 3 3 3 2 Protein of unknown function (DUF3801) CAF-1_p150 PF11600.3 CDI73934.1 - 0.0022 17.3 8.8 0.0022 17.3 6.1 7.2 7 1 0 7 7 7 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF4414 PF14377.1 CDI73935.1 - 2.2e-12 46.8 0.4 1e-06 28.6 0.0 14.0 10 5 1 11 11 11 3 Domain of unknown function (DUF4414) DUF2933 PF11666.3 CDI73935.1 - 0.17 11.4 3.2 2.9 7.5 1.0 3.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2933) SMN PF06003.7 CDI73936.1 - 6.4 5.7 14.2 9.7 5.2 9.8 1.3 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) NDK PF00334.14 CDI73937.1 - 9.9e-18 64.2 0.0 1.7e-10 40.7 0.0 3.5 2 1 1 3 3 3 3 Nucleoside diphosphate kinase GTP_EFTU PF00009.22 CDI73941.1 - 1.5e-14 53.8 0.0 3.2e-14 52.7 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 CDI73941.1 - 0.03 14.2 0.0 0.044 13.7 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase Dynamin_N PF00350.18 CDI73941.1 - 0.091 12.5 0.0 0.5 10.1 0.0 1.9 2 0 0 2 2 2 0 Dynamin family IBR PF01485.16 CDI73941.1 - 0.21 11.4 3.4 7.5 6.5 2.3 2.2 1 1 0 1 1 1 0 IBR domain FACT-Spt16_Nlob PF14826.1 CDI73942.1 - 0.00058 19.4 0.3 0.0012 18.3 0.0 1.7 2 0 0 2 2 2 1 FACT complex subunit SPT16 N-terminal lobe domain Carot_N PF09150.5 CDI73942.1 - 0.037 13.7 1.1 0.037 13.7 0.7 3.6 2 1 2 4 4 4 0 Orange carotenoid protein, N-terminal Peptidase_S64 PF08192.6 CDI73942.1 - 0.17 10.2 8.3 0.21 9.8 5.7 1.1 1 0 0 1 1 1 0 Peptidase family S64 Transketolase_N PF00456.16 CDI73945.1 - 1.8e-137 457.6 0.0 9.7e-137 455.2 0.0 1.8 2 0 0 2 2 2 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.19 CDI73945.1 - 6e-34 117.0 0.0 1.1e-33 116.2 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain DXP_synthase_N PF13292.1 CDI73945.1 - 4.2e-05 22.6 0.0 0.00056 18.9 0.0 2.1 1 1 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase Transketolase_C PF02780.15 CDI73945.1 - 0.00019 21.3 0.0 0.00039 20.3 0.0 1.6 1 0 0 1 1 1 1 Transketolase, C-terminal domain E1_dh PF00676.15 CDI73945.1 - 0.01 14.6 0.0 0.02 13.6 0.0 1.5 1 0 0 1 1 1 1 Dehydrogenase E1 component HTH_3 PF01381.17 CDI73946.1 - 8.7e-15 54.3 0.1 1.3e-14 53.7 0.1 1.3 1 0 0 1 1 1 1 Helix-turn-helix MBF1 PF08523.5 CDI73946.1 - 3.5e-12 46.1 6.0 8.3e-12 44.9 0.7 2.6 3 0 0 3 3 3 1 Multiprotein bridging factor 1 HTH_19 PF12844.2 CDI73946.1 - 2.8e-09 36.8 0.0 5.3e-09 35.9 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_31 PF13560.1 CDI73946.1 - 4.8e-08 33.0 0.0 7.8e-08 32.4 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_37 PF13744.1 CDI73946.1 - 0.014 15.2 0.0 0.023 14.4 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_26 PF13443.1 CDI73946.1 - 0.016 15.3 0.0 0.029 14.5 0.0 1.3 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain HTH_38 PF13936.1 CDI73946.1 - 0.055 13.0 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain Jun PF03957.8 CDI73946.1 - 0.062 13.0 0.0 0.072 12.8 0.0 1.1 1 0 0 1 1 1 0 Jun-like transcription factor HTH_25 PF13413.1 CDI73946.1 - 0.063 12.9 0.0 0.094 12.3 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain Dynein_light PF01221.13 CDI73948.1 - 4.5e-39 132.3 0.8 5.4e-39 132.0 0.6 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 UCH PF00443.24 CDI73948.1 - 0.14 11.2 0.1 0.17 10.9 0.0 1.1 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase DUF4106 PF13388.1 CDI73949.1 - 0.091 11.7 2.5 0.16 10.9 1.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) Herpes_TAF50 PF03326.8 CDI73950.1 - 0.015 14.2 16.3 0.031 13.2 5.9 2.1 2 0 0 2 2 2 0 Herpesvirus transcription activation factor (transactivator) DUF572 PF04502.8 CDI73950.1 - 0.028 13.6 15.1 0.021 14.0 5.3 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF572) Med3 PF11593.3 CDI73950.1 - 1.3 8.1 19.4 0.06 12.5 6.9 2.2 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal eIF3g PF12353.3 CDI73950.1 - 2.3 8.1 8.9 0.16 11.9 1.6 2.3 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit G Pkinase PF00069.20 CDI73951.1 - 4.3e-29 101.4 0.0 6.3e-29 100.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDI73951.1 - 2.3e-12 46.5 0.0 4.1e-12 45.7 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 CDI73951.1 - 4.7e-05 23.2 15.5 0.0011 18.7 0.1 4.1 4 1 0 4 4 4 2 Phosphotransferase enzyme family Kdo PF06293.9 CDI73951.1 - 0.012 14.6 0.1 0.044 12.8 0.0 1.9 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family TPR_11 PF13414.1 CDI73952.1 - 9.4e-35 118.0 12.3 3.7e-19 68.1 0.9 3.8 3 1 1 4 4 4 4 TPR repeat TPR_1 PF00515.23 CDI73952.1 - 3.2e-32 108.7 15.6 4.1e-09 35.6 0.0 5.3 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_2 PF07719.12 CDI73952.1 - 7.2e-26 87.9 12.8 9.2e-07 28.3 0.0 5.3 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_12 PF13424.1 CDI73952.1 - 2.3e-18 65.9 1.6 3.4e-09 36.5 0.3 3.2 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 CDI73952.1 - 8e-14 51.8 0.8 0.00023 21.7 0.0 3.6 2 2 1 3 3 3 3 Tetratricopeptide repeat TPR_17 PF13431.1 CDI73952.1 - 1.8e-11 43.2 4.5 0.014 15.5 0.0 5.4 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.1 CDI73952.1 - 2.2e-11 43.3 0.2 0.068 13.8 0.0 5.2 3 1 2 5 5 5 4 Tetratricopeptide repeat TPR_8 PF13181.1 CDI73952.1 - 2.6e-11 42.4 11.2 0.011 15.4 0.0 5.4 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_7 PF13176.1 CDI73952.1 - 1.6e-10 40.0 2.5 4.1e-05 23.0 0.2 4.4 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_9 PF13371.1 CDI73952.1 - 4.3e-09 36.0 0.2 0.0012 18.7 0.0 3.8 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 CDI73952.1 - 3.1e-07 30.6 3.1 0.16 12.3 0.0 4.0 2 2 2 4 4 4 3 Tetratricopeptide repeat Apc3 PF12895.2 CDI73952.1 - 1.8e-05 24.7 8.1 0.16 12.0 0.0 3.3 1 1 2 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 Fis1_TPR_C PF14853.1 CDI73952.1 - 0.00019 21.2 7.7 0.5 10.2 0.0 4.7 5 0 0 5 5 5 2 Fis1 C-terminal tetratricopeptide repeat TPR_6 PF13174.1 CDI73952.1 - 0.0015 18.8 6.7 0.22 12.0 0.4 4.0 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_10 PF13374.1 CDI73952.1 - 0.0034 17.2 0.7 0.041 13.8 0.0 3.0 4 0 0 4 4 3 1 Tetratricopeptide repeat DnaI_N PF07319.6 CDI73952.1 - 0.025 14.8 2.8 0.052 13.7 0.4 2.5 2 1 1 3 3 3 0 Primosomal protein DnaI N-terminus PPR PF01535.15 CDI73952.1 - 0.13 12.2 0.9 0.41 10.7 0.1 2.3 2 0 0 2 2 1 0 PPR repeat FKBP_N PF01346.13 CDI73952.1 - 0.21 11.6 6.5 2.4 8.2 0.2 2.4 2 0 0 2 2 2 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase DUF2407_C PF13373.1 CDI73953.1 - 0.0065 16.3 0.8 0.0065 16.3 0.5 9.1 5 3 0 6 6 6 1 DUF2407 C-terminal domain Ala_racemase_C PF00842.16 CDI73955.1 - 1 8.7 4.5 9.1 5.7 0.0 3.9 4 1 1 5 5 5 0 Alanine racemase, C-terminal domain Peptidase_M24 PF00557.19 CDI73956.1 - 0.15 11.6 1.6 0.23 11.0 1.1 1.3 1 0 0 1 1 1 0 Metallopeptidase family M24 DEAD PF00270.24 CDI73957.1 - 8.2e-17 61.2 2.9 3.5e-13 49.3 0.0 3.0 3 1 0 3 3 3 2 DEAD/DEAH box helicase ResIII PF04851.10 CDI73957.1 - 5.9e-07 29.4 0.0 5.9e-07 29.4 0.0 3.0 2 1 1 3 3 3 1 Type III restriction enzyme, res subunit AAA_19 PF13245.1 CDI73957.1 - 0.049 13.3 0.2 0.41 10.4 0.0 2.3 2 0 0 2 2 2 0 Part of AAA domain OmpH PF03938.9 CDI73957.1 - 0.76 9.7 49.4 1.8 8.4 34.2 1.7 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF3337 PF11816.3 CDI73957.1 - 2.7 7.3 40.1 4.2 6.6 27.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3337) Med15 PF09606.5 CDI73957.1 - 3 5.9 69.1 4.3 5.4 47.9 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal PAT1 PF09770.4 CDI73957.1 - 5.1 5.1 56.8 7.1 4.7 39.4 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Peptidase_M28 PF04389.12 CDI73958.1 - 1.9e-17 63.5 0.0 2.1e-16 60.2 0.0 2.8 1 1 0 1 1 1 1 Peptidase family M28 RskA PF10099.4 CDI73958.1 - 0.015 15.0 0.3 0.015 15.0 0.2 11.6 8 4 3 11 11 11 0 Anti-sigma-K factor rskA Spt20 PF12090.3 CDI73958.1 - 0.059 12.7 8.1 0.16 11.3 0.9 2.5 2 0 0 2 2 2 0 Spt20 family Mit_ribos_Mrp51 PF11709.3 CDI73958.1 - 0.18 10.9 13.0 1.4 8.0 0.1 3.4 3 0 0 3 3 3 0 Mitochondrial ribosomal protein subunit RAB3GAP2_N PF14655.1 CDI73958.1 - 0.98 8.3 12.4 0.46 9.4 2.6 2.5 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Activator_LAG-3 PF11498.3 CDI73961.1 - 0.00037 19.3 28.4 0.00037 19.3 19.7 15.3 6 2 9 16 16 16 3 Transcriptional activator LAG-3 N6_N4_Mtase PF01555.13 CDI73961.1 - 3 7.2 13.1 17 4.7 0.7 6.5 5 2 0 5 5 5 0 DNA methylase SDA1 PF05285.7 CDI73962.1 - 0.00038 19.8 29.5 0.00038 19.8 20.5 2.4 2 0 0 2 2 2 2 SDA1 CAF-1_p150 PF11600.3 CDI73962.1 - 0.0025 17.2 17.0 0.0025 17.2 11.8 2.5 3 0 0 3 3 3 2 Chromatin assembly factor 1 complex p150 subunit, N-terminal CDC45 PF02724.9 CDI73962.1 - 0.11 10.5 55.9 0.14 10.1 19.0 2.1 2 0 0 2 2 2 0 CDC45-like protein SPX PF03105.14 CDI73962.1 - 1.3 8.7 37.1 0.6 9.8 12.6 2.3 2 0 0 2 2 2 0 SPX domain Pox_Ag35 PF03286.9 CDI73962.1 - 1.9 7.9 47.1 0.17 11.4 15.1 2.3 2 0 0 2 2 2 0 Pox virus Ag35 surface protein Nop14 PF04147.7 CDI73962.1 - 2.1 6.1 67.4 0.032 12.1 27.1 2.1 2 0 0 2 2 2 0 Nop14-like family DUF2457 PF10446.4 CDI73962.1 - 2.2 6.9 63.6 0.23 10.1 28.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) Ycf1 PF05758.7 CDI73962.1 - 2.8 5.5 44.6 1.5 6.4 10.4 2.1 2 0 0 2 2 2 0 Ycf1 DUF2052 PF09747.4 CDI73962.1 - 4.5 7.1 64.5 1.7 8.5 17.5 2.5 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) SID-1_RNA_chan PF13965.1 CDI73962.1 - 9.9 4.1 23.0 0.74 7.9 2.4 2.3 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 Brix PF04427.13 CDI73964.1 - 2.6e-25 89.1 0.1 4.8e-25 88.3 0.1 1.4 1 0 0 1 1 1 1 Brix domain Asp-B-Hydro_N PF05279.6 CDI73964.1 - 1.7 8.4 7.8 2.4 7.9 5.4 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region SET PF00856.23 CDI73965.1 - 5.3e-07 30.0 0.0 5.3e-07 30.0 0.0 3.5 2 1 0 2 2 2 1 SET domain CTNNBL PF08216.6 CDI73965.1 - 0.11 12.0 0.1 0.11 12.0 0.1 2.3 2 0 0 2 2 2 0 Catenin-beta-like, Arm-motif containing nuclear Mon1 PF03164.9 CDI73966.1 - 8.4e-44 149.8 0.0 3.4e-20 72.0 0.0 3.0 2 1 0 2 2 2 2 Trafficking protein Mon1 dUTPase_2 PF08761.6 CDI73967.1 - 0.0027 17.8 1.4 0.0038 17.3 0.2 1.8 2 0 0 2 2 2 1 dUTPase UCH PF00443.24 CDI73967.1 - 0.96 8.5 5.2 1.4 7.9 3.6 1.4 1 1 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase DUF1645 PF07816.6 CDI73967.1 - 3.7 7.9 6.0 0.4 11.1 0.4 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF1645) Corona_nucleoca PF00937.13 CDI73968.1 - 0.00028 19.9 0.7 0.00049 19.1 0.5 1.4 1 0 0 1 1 1 1 Coronavirus nucleocapsid protein Peptidase_S49_N PF08496.5 CDI73968.1 - 0.022 14.5 6.8 0.88 9.3 2.6 2.7 2 0 0 2 2 2 0 Peptidase family S49 N-terminal ANP PF00212.13 CDI73968.1 - 0.18 11.9 1.1 0.6 10.2 0.8 2.0 1 0 0 1 1 1 0 Atrial natriuretic peptide GTPase_Cys_C PF12631.2 CDI73968.1 - 2.9 8.3 11.8 0.75 10.2 0.2 4.2 4 0 0 4 4 4 0 Catalytic cysteine-containing C-terminus of GTPase, MnmE DUF2439 PF10382.4 CDI73977.1 - 9e-06 25.8 0.0 2.6e-05 24.3 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF2439) NDUF_B12 PF08122.7 CDI73977.1 - 0.094 12.4 0.2 0.25 11.1 0.1 1.7 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase B12 subunit family CMV_1a PF12467.3 CDI73977.1 - 0.64 10.3 4.7 9.1 6.6 0.4 2.7 2 0 0 2 2 2 0 Cucumber mosaic virus 1a protein family TrmE_N PF10396.4 CDI73980.1 - 1.4e-05 25.0 3.4 2.6e-05 24.1 0.0 2.9 1 1 2 3 3 3 1 GTP-binding protein TrmE N-terminus Ribosomal_60s PF00428.14 CDI73980.1 - 0.028 14.7 12.8 0.028 14.7 8.9 5.3 3 1 1 4 4 4 0 60s Acidic ribosomal protein Activator_LAG-3 PF11498.3 CDI73980.1 - 0.19 10.4 23.3 0.048 12.4 8.4 2.3 2 0 0 2 2 2 0 Transcriptional activator LAG-3 DUF2232 PF09991.4 CDI73980.1 - 0.42 9.5 2.5 0.62 8.9 1.7 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) DUF413 PF04219.7 CDI73980.1 - 0.46 10.2 3.0 7.9 6.3 0.2 2.6 2 1 0 2 2 2 0 Protein of unknown function, DUF DUF4259 PF14078.1 CDI73980.1 - 1.4 9.4 11.6 5.6 7.4 1.9 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4259) SseC PF04888.7 CDI73983.1 - 0.0035 16.7 36.2 0.0035 16.7 25.1 5.3 4 1 1 5 5 5 1 Secretion system effector C (SseC) like family FluMu_gp41 PF10109.4 CDI73983.1 - 0.37 10.7 0.0 0.37 10.7 0.0 3.6 4 0 0 4 4 4 0 Mu-like prophage FluMu protein gp41 MCPVI PF02993.9 CDI73984.1 - 1 9.4 10.2 1.2 9.2 7.1 1.1 1 0 0 1 1 1 0 Minor capsid protein VI MIP-T3 PF10243.4 CDI73985.1 - 0.061 11.7 43.6 0.067 11.6 30.3 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DUF1777 PF08648.7 CDI73985.1 - 1.8 8.3 84.7 18 4.9 28.3 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1777) Sporozoite_P67 PF05642.6 CDI73987.1 - 0.59 7.9 6.2 0.6 7.9 4.3 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Amastin PF07344.6 CDI73987.1 - 1.1 8.8 6.0 1.5 8.4 4.1 1.2 1 0 0 1 1 1 0 Amastin surface glycoprotein DUF726 PF05277.7 CDI73988.1 - 3.5 6.4 9.6 4.3 6.1 6.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF726) FHA PF00498.21 CDI73989.1 - 7.1e-11 42.0 0.0 1.2e-10 41.2 0.0 1.4 1 0 0 1 1 1 1 FHA domain Oxidored_q3 PF00499.15 CDI73990.1 - 0.039 13.7 0.6 0.055 13.2 0.4 1.3 1 1 0 1 1 1 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 Presenilin PF01080.12 CDI73990.1 - 5.3 5.7 11.3 6.3 5.5 7.8 1.1 1 0 0 1 1 1 0 Presenilin PLRV_ORF5 PF01690.12 CDI73990.1 - 8.7 5.3 17.9 10 5.0 12.4 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein SR-25 PF10500.4 CDI73991.1 - 1.4e-05 24.6 21.3 1.4e-05 24.6 14.8 2.3 2 0 0 2 2 1 1 Nuclear RNA-splicing-associated protein Shisa PF13908.1 CDI73991.1 - 0.0014 18.8 4.6 0.0014 18.8 3.2 2.3 2 0 0 2 2 2 1 Wnt and FGF inhibitory regulator LMBR1 PF04791.11 CDI73991.1 - 0.0021 16.7 0.1 0.026 13.1 0.0 2.1 1 1 1 2 2 1 1 LMBR1-like membrane protein Spc7_N PF15402.1 CDI73991.1 - 0.0022 16.1 11.2 0.0022 16.1 7.8 2.1 2 0 0 2 2 1 1 N-terminus of kinetochore NMS complex subunit Spc7 Serinc PF03348.10 CDI73991.1 - 0.0026 16.5 4.2 0.0026 16.5 2.9 2.2 2 0 0 2 2 2 1 Serine incorporator (Serinc) IncA PF04156.9 CDI73991.1 - 0.0033 17.0 19.3 0.0033 17.0 13.4 3.2 2 1 1 3 3 2 1 IncA protein Spt20 PF12090.3 CDI73991.1 - 0.0042 16.4 22.4 0.0093 15.3 2.5 2.3 2 0 0 2 2 2 2 Spt20 family SPX PF03105.14 CDI73991.1 - 0.0065 16.2 6.1 0.0065 16.2 4.2 2.0 2 0 0 2 2 2 1 SPX domain FAM176 PF14851.1 CDI73991.1 - 0.011 15.3 3.3 0.011 15.3 2.3 2.5 2 1 0 2 2 2 0 FAM176 family N6_N4_Mtase PF01555.13 CDI73991.1 - 0.019 14.4 0.1 0.28 10.6 0.0 2.2 1 1 0 1 1 1 0 DNA methylase PIG-P PF08510.7 CDI73991.1 - 0.028 14.0 2.2 0.57 9.8 0.1 2.4 2 0 0 2 2 2 0 PIG-P Sporozoite_P67 PF05642.6 CDI73991.1 - 0.031 12.1 11.2 0.055 11.3 7.7 1.4 1 1 0 1 1 1 0 Sporozoite P67 surface antigen DUF1510 PF07423.6 CDI73991.1 - 0.052 12.8 33.2 0.031 13.6 5.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) CDC45 PF02724.9 CDI73991.1 - 0.093 10.7 22.8 0.1 10.6 0.7 2.1 2 0 0 2 2 2 0 CDC45-like protein Suf PF05843.9 CDI73991.1 - 0.093 12.4 30.6 0.033 13.9 2.4 2.1 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) RR_TM4-6 PF06459.7 CDI73991.1 - 0.097 12.5 33.0 0.078 12.8 6.4 2.4 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 PEX11 PF05648.9 CDI73991.1 - 0.3 10.3 10.3 0.38 9.9 1.0 2.5 2 0 0 2 2 2 0 Peroxisomal biogenesis factor 11 (PEX11) DUF4131 PF13567.1 CDI73991.1 - 0.3 10.4 0.0 0.3 10.4 0.0 2.9 2 1 1 3 3 1 0 Domain of unknown function (DUF4131) SAGA-Tad1 PF12767.2 CDI73991.1 - 0.35 10.5 26.0 0.067 12.8 7.1 2.1 2 0 0 2 2 2 0 Transcriptional regulator of RNA polII, SAGA, subunit GAGA_bind PF06217.7 CDI73991.1 - 0.62 9.9 24.6 0.11 12.4 1.7 2.1 2 0 0 2 2 2 0 GAGA binding protein-like family Ycf1 PF05758.7 CDI73991.1 - 0.67 7.5 25.2 0.28 8.8 4.7 2.0 2 0 0 2 2 2 0 Ycf1 Raftlin PF15250.1 CDI73991.1 - 0.73 8.2 23.4 0.18 10.3 1.0 2.1 2 0 0 2 2 2 0 Raftlin TT_ORF1 PF02956.9 CDI73991.1 - 0.76 8.1 14.3 0.44 8.9 1.5 2.0 2 0 0 2 2 2 0 TT viral orf 1 DUF737 PF05300.6 CDI73991.1 - 0.86 9.5 37.7 0.4 10.6 12.7 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF737) MLANA PF14991.1 CDI73991.1 - 0.92 9.5 9.1 0.37 10.8 0.3 2.4 2 0 0 2 2 2 0 Protein melan-A SID-1_RNA_chan PF13965.1 CDI73991.1 - 1 7.4 19.0 0.046 11.8 2.3 2.1 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 FLO_LFY PF01698.11 CDI73991.1 - 2.7 6.7 25.2 0.28 9.9 1.6 2.2 2 0 0 2 2 2 0 Floricaula / Leafy protein CPSF100_C PF13299.1 CDI73991.1 - 3 8.0 21.3 0.98 9.5 1.5 2.3 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal DUF2052 PF09747.4 CDI73991.1 - 4.4 7.1 38.6 0.018 14.9 9.1 2.1 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) PAT1 PF09770.4 CDI73991.1 - 5.3 5.1 47.2 0.25 9.5 14.3 2.1 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 AUX_IAA PF02309.11 CDI73991.1 - 6.7 6.3 27.0 1.1 9.0 7.1 2.2 2 0 0 2 2 2 0 AUX/IAA family Band_3_cyto PF07565.8 CDI73991.1 - 8.6 5.7 30.3 0.37 10.2 8.0 2.1 2 0 0 2 2 2 0 Band 3 cytoplasmic domain AAA_11 PF13086.1 CDI73991.1 - 9.4 5.7 23.9 0.87 9.1 2.3 2.2 2 0 0 2 2 2 0 AAA domain Dehydrin PF00257.14 CDI73992.1 - 0.00016 22.0 8.7 0.016 15.5 6.2 6.8 3 2 1 4 4 4 2 Dehydrin SR-25 PF10500.4 CDI73992.1 - 0.0013 18.2 10.9 0.0013 18.2 7.5 7.7 7 1 0 7 7 7 1 Nuclear RNA-splicing-associated protein PRP21_like_P PF12230.3 CDI73992.1 - 0.003 17.0 10.4 0.003 17.0 7.2 6.1 5 1 0 5 5 5 1 Pre-mRNA splicing factor PRP21 like protein Med15 PF09606.5 CDI73992.1 - 0.0081 14.4 1.0 0.0081 14.4 0.7 4.0 3 1 1 5 5 5 1 ARC105 or Med15 subunit of Mediator complex non-fungal DUF4496 PF14908.1 CDI73992.1 - 0.016 15.0 1.8 0.016 15.0 1.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4496) SDA1 PF05285.7 CDI73992.1 - 0.12 11.6 0.0 0.12 11.6 0.0 4.8 3 1 2 5 5 5 0 SDA1 HA2 PF04408.18 CDI73992.1 - 0.13 12.2 0.2 0.13 12.2 0.1 5.8 5 1 0 5 5 5 0 Helicase associated domain (HA2) IncA PF04156.9 CDI73992.1 - 0.8 9.2 0.0 0.8 9.2 0.0 5.4 4 2 0 4 4 4 0 IncA protein DNMT1-RFD PF12047.3 CDI73994.1 - 1.7e-05 24.5 0.0 7.8e-05 22.4 0.0 2.2 1 0 0 1 1 1 1 Cytosine specific DNA methyltransferase replication foci domain FimP PF09766.4 CDI73994.1 - 0.0028 16.7 10.9 0.0028 16.7 7.6 18.1 10 4 9 19 19 19 2 Fms-interacting protein PBP1_TM PF14812.1 CDI73995.1 - 0.0016 18.7 4.7 0.0016 18.7 3.3 3.2 2 1 0 2 2 2 1 Transmembrane domain of transglycosylase PBP1 at N-terminal Phostensin_N PF13916.1 CDI73996.1 - 0.016 15.1 0.5 0.016 15.1 0.4 2.2 1 1 1 2 2 2 0 PP1-regulatory protein, Phostensin N-terminal SART-1 PF03343.8 CDI73996.1 - 0.023 13.0 7.6 0.026 12.8 5.3 1.0 1 0 0 1 1 1 0 SART-1 family WTX PF09422.5 CDI73996.1 - 0.048 12.6 4.5 0.052 12.5 3.1 1.1 1 0 0 1 1 1 0 WTX protein Myc_N PF01056.13 CDI73996.1 - 0.12 11.5 3.8 0.13 11.3 2.6 1.1 1 0 0 1 1 1 0 Myc amino-terminal region TraT PF05818.7 CDI73996.1 - 0.12 11.7 8.9 0.14 11.5 6.2 1.1 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein Helicase_RecD PF05127.9 CDI73996.1 - 0.61 9.7 4.9 0.78 9.3 3.4 1.1 1 0 0 1 1 1 0 Helicase Med15 PF09606.5 CDI73996.1 - 1.9 6.6 27.1 2.3 6.3 18.8 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal TFIIA PF03153.8 CDI73996.1 - 2.6 7.8 19.1 3 7.6 13.3 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit AIF_C PF14721.1 CDI73996.1 - 2.9 8.1 8.2 4.3 7.5 5.7 1.5 1 1 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term DGF-1_C PF11040.3 CDI73996.1 - 3.3 7.6 5.9 14 5.6 1.5 2.2 1 1 1 2 2 2 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus DUF1426 PF07234.6 CDI73996.1 - 4.1 7.1 5.3 3 7.5 2.7 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1426) Suf PF05843.9 CDI73996.1 - 5.8 6.5 9.9 6.4 6.4 6.9 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) PP2C PF00481.16 CDI73997.1 - 0.0022 17.4 0.0 0.0026 17.1 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C Chorion_2 PF03964.10 CDI73997.1 - 1.5 9.4 10.6 0.14 12.6 2.5 2.1 2 0 0 2 2 2 0 Chorion family 2 Ribosomal_60s PF00428.14 CDI73997.1 - 5.5 7.4 18.8 0.25 11.7 4.7 2.2 2 0 0 2 2 2 0 60s Acidic ribosomal protein 5_nucleotid_C PF02872.13 CDI73998.1 - 1.9e-35 122.1 0.0 6.1e-35 120.5 0.0 1.9 2 0 0 2 2 2 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.23 CDI73998.1 - 0.0022 17.4 0.4 0.032 13.6 0.3 2.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase F-box-like PF12937.2 CDI73999.1 - 0.003 17.2 2.1 0.0076 15.9 0.6 2.4 2 0 0 2 2 2 1 F-box-like DUF342 PF03961.8 CDI73999.1 - 0.074 11.4 2.6 0.12 10.7 1.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF342) BAF1_ABF1 PF04684.8 CDI73999.1 - 0.79 8.4 0.0 0.79 8.4 0.0 2.5 2 1 0 3 3 3 0 BAF1 / ABF1 chromatin reorganising factor FA_desaturase PF00487.19 CDI74000.1 - 2.8e-11 43.3 13.6 2.8e-11 43.3 9.4 3.8 3 1 1 4 4 4 2 Fatty acid desaturase OST3_OST6 PF04756.8 CDI74001.1 - 9.9e-08 31.7 0.2 3e-07 30.1 0.1 1.8 1 1 0 1 1 1 1 OST3 / OST6 family Fcf1 PF04900.7 CDI74002.1 - 3.1e-36 123.5 1.1 3.1e-36 123.5 0.7 2.1 2 0 0 2 2 2 1 Fcf1 DUF1183 PF06682.7 CDI74002.1 - 1.7e-05 24.6 0.3 3e-05 23.7 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1183) PIN PF01850.16 CDI74002.1 - 0.051 13.9 0.1 4.9 7.5 0.0 2.4 1 1 1 2 2 2 0 PIN domain IncA PF04156.9 CDI74003.1 - 0.56 9.7 23.2 2.5 7.6 10.4 2.2 2 0 0 2 2 2 0 IncA protein DUF2205 PF10224.4 CDI74003.1 - 1.1 8.8 14.8 0.33 10.5 1.6 3.4 3 0 0 3 3 3 0 Predicted coiled-coil protein (DUF2205) DUF745 PF05335.8 CDI74003.1 - 4.3 6.8 19.2 0.25 10.8 5.1 2.9 2 1 2 4 4 4 0 Protein of unknown function (DUF745) TMPIT PF07851.8 CDI74003.1 - 5.3 6.0 9.3 1.4 7.9 4.1 1.7 2 0 0 2 2 2 0 TMPIT-like protein DUF4201 PF13870.1 CDI74003.1 - 5.3 6.4 26.0 4.4 6.7 1.4 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4201) Rootletin PF15035.1 CDI74003.1 - 6.4 6.7 26.5 0.46 10.4 9.2 3.1 2 1 1 3 3 3 0 Ciliary rootlet component, centrosome cohesion Atg14 PF10186.4 CDI74003.1 - 8.1 5.2 22.1 0.62 8.9 0.4 2.2 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 YscO PF07321.7 CDI74003.1 - 9.5 6.0 29.5 1.8 8.4 4.6 3.2 2 1 1 3 3 3 0 Type III secretion protein YscO Utp14 PF04615.8 CDI74004.1 - 0.28 9.2 41.0 0.34 9.0 28.4 1.1 1 0 0 1 1 1 0 Utp14 protein Nop53 PF07767.6 CDI74004.1 - 0.76 8.7 42.6 1.1 8.2 29.5 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) GAGA_bind PF06217.7 CDI74004.1 - 1.7 8.5 45.1 2.1 8.2 31.2 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family DUF4045 PF13254.1 CDI74004.1 - 7 5.8 40.6 9.7 5.3 28.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) AAA_23 PF13476.1 CDI74005.1 - 0.0095 16.2 1.5 0.0095 16.2 1.0 2.2 2 0 0 2 2 2 1 AAA domain DUF3829 PF12889.2 CDI74005.1 - 2.5 7.2 11.1 0.51 9.4 3.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3829) DUF3371 PF11851.3 CDI74005.1 - 4.6 7.9 25.1 0.84 10.3 2.2 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF3371) DUF2048 PF09752.4 CDI74005.1 - 5.7 5.7 13.4 0.015 14.2 1.9 2.0 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2048) DUF2232 PF09991.4 CDI74005.1 - 7.5 5.4 10.5 0.27 10.1 2.3 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2232) DEAD PF00270.24 CDI74006.1 - 3.1e-14 52.8 10.0 1.2e-10 41.1 4.2 6.8 6 1 0 6 6 6 2 DEAD/DEAH box helicase Helicase_C PF00271.26 CDI74006.1 - 0.00026 20.7 0.0 0.00026 20.7 0.0 6.6 8 0 0 8 8 8 1 Helicase conserved C-terminal domain BRF1 PF07741.8 CDI74008.1 - 0.015 15.5 0.9 0.015 15.5 0.6 6.6 3 1 2 5 5 5 0 Brf1-like TBP-binding domain BAF1_ABF1 PF04684.8 CDI74010.1 - 0.0044 15.9 14.7 0.0044 15.9 10.2 5.2 4 1 1 5 5 5 1 BAF1 / ABF1 chromatin reorganising factor SR-25 PF10500.4 CDI74010.1 - 0.012 15.1 3.4 0.012 15.1 2.4 3.3 3 0 0 3 3 3 0 Nuclear RNA-splicing-associated protein PAT1 PF09770.4 CDI74010.1 - 0.28 9.3 22.6 0.31 9.2 15.6 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Peptidase_S49_N PF08496.5 CDI74011.1 - 0.26 11.0 6.1 0.12 12.1 2.0 2.0 2 0 0 2 2 2 0 Peptidase family S49 N-terminal DUF3801 PF12687.2 CDI74011.1 - 2.5 7.6 15.8 5.6 6.4 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3801) Serinc PF03348.10 CDI74011.1 - 6.1 5.4 8.5 0.65 8.6 2.7 1.8 2 0 0 2 2 2 0 Serine incorporator (Serinc) Band_3_cyto PF07565.8 CDI74011.1 - 7.6 5.9 14.8 12 5.3 5.2 2.4 2 0 0 2 2 2 0 Band 3 cytoplasmic domain FimP PF09766.4 CDI74011.1 - 7.7 5.4 22.8 0.17 10.9 9.4 2.2 2 0 0 2 2 2 0 Fms-interacting protein Methyltransf_5 PF01795.14 CDI74013.1 - 9.6e-28 97.3 7.2 1.3e-17 64.0 0.3 2.8 3 0 0 3 3 3 2 MraW methylase family Spore_coat_CotO PF14153.1 CDI74013.1 - 2.1e-05 24.0 7.1 2.1e-05 24.0 4.9 2.2 2 0 0 2 2 2 1 Spore coat protein CotO SAPS PF04499.10 CDI74013.1 - 0.00017 20.4 1.3 0.00043 19.0 0.9 1.6 1 1 0 1 1 1 1 SIT4 phosphatase-associated protein Plasmodium_Vir PF05795.6 CDI74013.1 - 0.0019 17.4 1.4 0.0032 16.7 0.2 1.8 2 0 0 2 2 2 1 Plasmodium vivax Vir protein SPX PF03105.14 CDI74013.1 - 0.0031 17.3 5.6 0.0099 15.6 0.2 2.7 3 0 0 3 3 3 1 SPX domain DUF4557 PF15101.1 CDI74013.1 - 0.052 13.3 29.3 0.1 12.4 12.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4557) AFT PF08731.6 CDI74013.1 - 0.067 13.3 10.3 0.35 11.0 5.2 2.3 2 0 0 2 2 2 0 Transcription factor AFT Otopetrin PF03189.8 CDI74013.1 - 0.081 11.9 0.4 0.3 10.0 0.0 1.9 2 0 0 2 2 2 0 Otopetrin DUF1764 PF08576.5 CDI74013.1 - 0.14 12.9 21.8 2.1 9.1 10.3 2.4 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF1764) SAGA-Tad1 PF12767.2 CDI74013.1 - 0.28 10.8 25.0 0.26 10.9 7.8 2.2 2 0 0 2 2 2 0 Transcriptional regulator of RNA polII, SAGA, subunit eIF-3_zeta PF05091.7 CDI74013.1 - 0.29 9.6 21.7 0.1 11.2 9.0 2.1 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Tim54 PF11711.3 CDI74013.1 - 0.36 9.3 11.2 0.45 9.0 5.6 2.0 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 AAA_11 PF13086.1 CDI74013.1 - 0.5 9.8 17.5 0.38 10.3 6.6 2.2 2 0 0 2 2 2 0 AAA domain Raftlin PF15250.1 CDI74013.1 - 0.69 8.3 17.0 2.3 6.6 7.6 2.0 2 0 0 2 2 2 0 Raftlin CRF1 PF10380.4 CDI74013.1 - 0.9 9.8 14.9 0.19 12.0 3.9 2.5 3 0 0 3 3 2 0 Transcription factor CRF1 Band_3_cyto PF07565.8 CDI74013.1 - 0.96 8.8 17.9 2.9 7.3 8.1 2.3 2 0 0 2 2 2 0 Band 3 cytoplasmic domain DUF2828 PF11443.3 CDI74013.1 - 1.2 7.2 12.3 1.5 6.9 4.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF2828) Gti1_Pac2 PF09729.4 CDI74013.1 - 1.4 8.7 14.6 0.033 14.0 1.2 2.5 2 1 0 2 2 2 0 Gti1/Pac2 family Cellulose_synt PF03552.9 CDI74013.1 - 1.5 7.0 6.0 0.43 8.8 1.6 1.7 2 0 0 2 2 2 0 Cellulose synthase DUF4011 PF13195.1 CDI74013.1 - 1.8 8.5 11.8 1.2 9.1 3.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4011) CDC45 PF02724.9 CDI74013.1 - 2.2 6.1 15.5 0.25 9.3 5.9 2.1 2 0 0 2 2 2 0 CDC45-like protein AUX_IAA PF02309.11 CDI74013.1 - 2.6 7.7 14.5 2.2 7.9 5.5 2.3 2 0 0 2 2 2 0 AUX/IAA family DUF3395 PF11875.3 CDI74013.1 - 3.4 7.2 22.9 0.12 11.9 8.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3395) Suf PF05843.9 CDI74013.1 - 3.5 7.2 26.9 2.3 7.9 1.5 2.2 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) Rxt3 PF08642.5 CDI74013.1 - 4.5 7.5 7.1 4.4 7.5 1.6 2.3 2 0 0 2 2 2 0 Histone deacetylation protein Rxt3 PAT1 PF09770.4 CDI74013.1 - 4.5 5.4 47.9 0.76 7.9 19.6 2.1 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 Baculo_PP31 PF05311.6 CDI74013.1 - 5.6 6.1 18.6 2.5 7.2 7.6 2.2 2 0 0 2 2 2 0 Baculovirus 33KDa late protein (PP31) CPSF100_C PF13299.1 CDI74013.1 - 5.7 7.0 16.9 3.9 7.6 7.4 2.3 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal Eapp_C PF10238.4 CDI74013.1 - 7 6.5 17.9 6.1 6.7 7.9 2.6 2 0 0 2 2 2 0 E2F-associated phosphoprotein LMBR1 PF04791.11 CDI74013.1 - 7.7 4.9 6.7 11 4.5 2.3 2.0 2 0 0 2 2 2 0 LMBR1-like membrane protein DUF572 PF04502.8 CDI74013.1 - 8.3 5.5 23.7 6 5.9 8.7 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF572) DUF2407_C PF13373.1 CDI74013.1 - 8.7 6.2 11.0 31 4.4 0.1 2.3 2 0 0 2 2 2 0 DUF2407 C-terminal domain FimP PF09766.4 CDI74013.1 - 9.6 5.1 39.7 1.9 7.4 2.8 2.1 2 0 0 2 2 2 0 Fms-interacting protein PPP4R2 PF09184.6 CDI74014.1 - 3.1 7.2 17.2 3.6 7.0 11.9 1.0 1 0 0 1 1 1 0 PPP4R2 Spore_coat_CotO PF14153.1 CDI74014.1 - 9.5 5.6 20.2 13 5.2 14.0 1.3 1 0 0 1 1 1 0 Spore coat protein CotO Med15 PF09606.5 CDI74015.1 - 0.0037 15.5 71.5 0.0044 15.2 49.6 1.1 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal Utp14 PF04615.8 CDI74015.1 - 0.028 12.6 30.1 0.032 12.4 20.9 1.0 1 0 0 1 1 1 0 Utp14 protein Plant_all_beta PF10532.4 CDI74015.1 - 0.038 14.0 0.3 0.038 14.0 0.2 2.4 1 1 1 2 2 2 0 Plant specific N-all beta domain PAT1 PF09770.4 CDI74015.1 - 0.044 12.0 57.2 0.054 11.7 39.7 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Pneumo_phosprot PF02478.11 CDI74015.1 - 1.3 8.4 15.8 2 7.8 11.0 1.2 1 0 0 1 1 1 0 Pneumovirus phosphoprotein Herpes_UL87 PF03043.9 CDI74015.1 - 6.1 5.1 15.3 8 4.7 10.6 1.2 1 0 0 1 1 1 0 Herpesvirus UL87 family cNMP_binding PF00027.24 CDI74016.1 - 4.2e-08 32.8 0.0 6.9e-08 32.2 0.0 1.3 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain CAF-1_p150 PF11600.3 CDI74016.1 - 5.1e-05 22.7 56.0 5.1e-05 22.7 38.8 1.4 2 0 0 2 2 2 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal SprA-related PF12118.3 CDI74016.1 - 0.00094 18.5 80.4 0.00094 18.5 55.7 2.0 2 0 0 2 2 2 1 SprA-related family RAP1 PF07218.6 CDI74016.1 - 0.0017 16.5 20.6 0.0022 16.1 14.3 1.2 1 0 0 1 1 1 1 Rhoptry-associated protein 1 (RAP-1) CDC27 PF09507.5 CDI74016.1 - 0.011 14.9 45.0 0.014 14.6 31.2 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 THRAP3_BCLAF1 PF15440.1 CDI74016.1 - 0.057 12.0 54.6 0.067 11.8 37.8 1.1 1 0 0 1 1 1 0 THRAP3/BCLAF1 family Methyltransf_18 PF12847.2 CDI74016.1 - 0.08 13.5 0.0 0.08 13.5 0.0 2.1 2 1 0 2 2 1 0 Methyltransferase domain Utp14 PF04615.8 CDI74016.1 - 0.1 10.7 44.9 0.12 10.5 31.1 1.1 1 0 0 1 1 1 0 Utp14 protein DUF3337 PF11816.3 CDI74016.1 - 0.14 11.5 32.4 0.17 11.2 22.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3337) Med15 PF09606.5 CDI74016.1 - 0.15 10.2 101.1 0.2 9.8 70.0 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal LMBR1 PF04791.11 CDI74016.1 - 0.3 9.6 17.8 0.36 9.3 12.4 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Hex_IIIa PF02455.11 CDI74016.1 - 2.5 6.6 30.3 4 6.0 21.0 1.3 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) Asp-B-Hydro_N PF05279.6 CDI74016.1 - 4.4 7.0 23.7 5.2 6.8 16.4 1.3 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Parvo_coat PF00740.13 CDI74016.1 - 6.8 5.5 34.3 8.2 5.2 23.7 1.2 1 0 0 1 1 1 0 Parvovirus coat protein VP2 AAA_23 PF13476.1 CDI74017.1 - 0.011 16.0 3.0 0.011 16.0 2.1 7.4 4 1 0 4 4 4 0 AAA domain PAT1 PF09770.4 CDI74018.1 - 2.4 6.2 99.4 3.1 5.9 68.9 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Nha1_C PF08619.5 CDI74018.1 - 2.8 7.1 37.5 3.9 6.6 26.0 1.2 1 0 0 1 1 1 0 Alkali metal cation/H+ antiporter Nha1 C terminus NicO PF03824.11 CDI74019.1 - 5.5 6.2 12.2 8.5 5.5 8.4 1.3 1 0 0 1 1 1 0 High-affinity nickel-transport protein tRNA-synt_1 PF00133.17 CDI74020.1 - 4.3e-09 34.9 25.5 1.7e-07 29.6 6.0 11.0 8 3 4 12 12 12 5 tRNA synthetases class I (I, L, M and V) UPF0564 PF10595.4 CDI74021.1 - 0.0028 16.6 13.0 0.0028 16.6 9.0 4.0 3 1 0 3 3 3 2 Uncharacterised protein family UPF0564 CAF-1_p150 PF11600.3 CDI74021.1 - 0.0045 16.4 38.4 0.0045 16.4 26.6 4.2 3 1 0 4 4 4 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal Ribosomal_60s PF00428.14 CDI74021.1 - 0.0049 17.2 5.4 0.0049 17.2 3.7 9.9 2 1 4 6 6 6 1 60s Acidic ribosomal protein SR-25 PF10500.4 CDI74021.1 - 0.0064 15.9 22.2 0.0064 15.9 15.4 5.7 4 1 0 4 4 4 2 Nuclear RNA-splicing-associated protein IncA PF04156.9 CDI74021.1 - 0.0086 15.6 14.9 0.0086 15.6 10.4 5.3 3 1 1 4 4 4 2 IncA protein Utp14 PF04615.8 CDI74021.1 - 2.2 6.3 83.4 0.21 9.7 27.0 3.1 3 0 0 3 3 3 0 Utp14 protein CDC27 PF09507.5 CDI74022.1 - 0.001 18.3 35.9 0.0013 18.0 24.9 1.0 1 0 0 1 1 1 1 DNA polymerase subunit Cdc27 PA26 PF04636.8 CDI74022.1 - 0.3 9.7 25.5 0.4 9.3 17.7 1.2 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Parvo_coat PF00740.13 CDI74022.1 - 1.5 7.6 42.8 1.6 7.5 29.7 1.0 1 0 0 1 1 1 0 Parvovirus coat protein VP2 GAGA_bind PF06217.7 CDI74022.1 - 2.1 8.2 38.2 3.4 7.5 26.5 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family PAT1 PF09770.4 CDI74022.1 - 4.4 5.4 102.8 5.3 5.1 71.2 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Sec23_trunk PF04811.10 CDI74023.1 - 3.3e-21 75.7 0.0 3.3e-21 75.7 0.0 2.7 4 0 0 4 4 4 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 CDI74023.1 - 1.5e-19 69.3 0.5 5.9e-19 67.4 0.3 2.2 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 CDI74023.1 - 3.3e-09 37.1 0.0 4.6e-08 33.4 0.0 2.9 2 0 0 2 2 2 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 CDI74023.1 - 5.8e-09 35.3 6.0 1.2e-08 34.3 4.2 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Peptidase_M18 PF02127.10 CDI74024.1 - 1.7e-129 432.1 0.0 4.9e-95 318.5 0.0 2.0 2 0 0 2 2 2 2 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.9 CDI74024.1 - 2.1e-06 26.7 0.0 4.9e-05 22.2 0.0 2.1 2 0 0 2 2 2 2 M42 glutamyl aminopeptidase Actin PF00022.14 CDI74026.1 - 1.9e-25 89.1 0.0 1.8e-23 82.6 0.0 2.8 1 1 0 1 1 1 1 Actin PPR_2 PF13041.1 CDI74027.1 - 1.4e-49 165.7 5.1 5e-15 55.2 0.0 6.3 2 1 4 6 6 6 6 PPR repeat family PPR_1 PF12854.2 CDI74027.1 - 1.4e-30 104.4 5.7 2e-08 33.5 0.0 7.4 7 0 0 7 7 7 6 PPR repeat PPR PF01535.15 CDI74027.1 - 3.7e-30 101.7 10.1 2.9e-06 26.8 0.0 8.7 8 2 0 8 8 8 7 PPR repeat PPR_3 PF13812.1 CDI74027.1 - 2.9e-28 95.7 5.7 4.1e-06 26.6 0.0 8.6 8 1 0 8 8 8 4 Pentatricopeptide repeat domain IncA PF04156.9 CDI74028.1 - 0.00034 20.2 3.0 0.00034 20.2 2.1 7.7 5 2 0 6 6 6 2 IncA protein HALZ PF02183.13 CDI74028.1 - 0.0087 15.7 1.9 0.0087 15.7 1.3 13.0 11 3 2 13 13 13 6 Homeobox associated leucine zipper PK PF00224.16 CDI74029.1 - 8.5e-53 179.1 0.1 2.5e-33 115.1 0.1 3.2 3 0 0 3 3 3 3 Pyruvate kinase, barrel domain Gly-zipper_YMGG PF13441.1 CDI74029.1 - 7.7e-06 25.3 0.6 7.7e-06 25.3 0.4 2.7 2 0 0 2 2 1 1 YMGG-like Gly-zipper Gly-zipper_Omp PF13488.1 CDI74029.1 - 0.0034 16.9 1.9 0.0034 16.9 1.3 2.6 2 0 0 2 2 1 1 Glycine zipper OmpH PF03938.9 CDI74029.1 - 0.033 14.1 40.1 0.068 13.0 3.4 3.6 3 0 0 3 3 3 0 Outer membrane protein (OmpH-like) HpcH_HpaI PF03328.9 CDI74029.1 - 0.043 12.6 2.5 4.4 6.1 0.4 2.6 2 1 0 2 2 2 0 HpcH/HpaI aldolase/citrate lyase family TFIIA PF03153.8 CDI74029.1 - 0.096 12.5 38.3 0.23 11.3 17.1 2.3 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit AAA_23 PF13476.1 CDI74029.1 - 0.11 12.7 19.6 5.3 7.3 0.4 3.3 3 0 0 3 3 3 0 AAA domain Pilus_PilP PF11356.3 CDI74029.1 - 0.52 10.5 0.0 0.52 10.5 0.0 3.9 4 0 0 4 4 4 0 Type IV pilus biogenesis DUF2052 PF09747.4 CDI74029.1 - 1.1 9.1 32.5 3 7.7 1.2 3.3 3 0 0 3 3 3 0 Coiled-coil domain containing protein (DUF2052) Usp PF00582.21 CDI74029.1 - 1.1 9.4 6.2 8.5 6.5 0.1 3.1 3 0 0 3 3 3 0 Universal stress protein family FimP PF09766.4 CDI74029.1 - 1.9 7.4 36.2 0.67 8.9 3.0 3.3 3 0 0 3 3 3 0 Fms-interacting protein DDRGK PF09756.4 CDI74029.1 - 4.6 6.6 30.0 2.8 7.2 4.1 3.2 3 0 0 3 3 3 0 DDRGK domain Neur_chan_memb PF02932.11 CDI74029.1 - 9.7 5.9 25.8 5.6 6.7 0.3 2.8 3 0 0 3 3 3 0 Neurotransmitter-gated ion-channel transmembrane region SR-25 PF10500.4 CDI74030.1 - 1.8e-07 30.8 19.9 1.8e-07 30.8 13.8 4.1 4 1 0 4 4 4 2 Nuclear RNA-splicing-associated protein SelP_N PF04592.9 CDI74030.1 - 0.00017 21.0 4.9 0.00017 21.0 3.4 3.5 4 0 0 4 4 4 2 Selenoprotein P, N terminal region BAF1_ABF1 PF04684.8 CDI74030.1 - 0.00072 18.5 9.8 0.00072 18.5 6.8 5.5 4 1 2 6 6 6 1 BAF1 / ABF1 chromatin reorganising factor SOBP PF15279.1 CDI74030.1 - 0.0057 17.0 36.9 0.091 13.1 13.1 2.3 2 0 0 2 2 2 2 Sine oculis-binding protein MFS_Mycoplasma PF07672.8 CDI74030.1 - 0.51 9.4 0.0 0.51 9.4 0.0 3.4 4 1 0 4 4 4 0 Mycoplasma MFS transporter AIF_C PF14721.1 CDI74030.1 - 2.2 8.5 38.6 5.3 7.2 1.1 4.4 4 0 0 4 4 4 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Dala_Dala_lig_N PF01820.16 CDI74030.1 - 10 6.4 20.6 5.6 7.2 3.0 4.3 4 0 0 4 4 4 0 D-ala D-ala ligase N-terminus TFIIF_alpha PF05793.7 CDI74033.1 - 0.0032 15.8 19.7 0.0035 15.7 13.7 1.0 1 0 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF1510 PF07423.6 CDI74033.1 - 0.017 14.5 24.6 0.021 14.1 17.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DNA_pol_viral_N PF00242.12 CDI74033.1 - 0.18 10.8 31.2 0.23 10.4 21.6 1.3 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain Mem_trans PF03547.13 CDI74033.1 - 0.18 10.0 12.4 0.2 9.9 8.6 1.1 1 0 0 1 1 1 0 Membrane transport protein SPX PF03105.14 CDI74033.1 - 0.25 11.0 23.1 0.29 10.8 16.0 1.2 1 0 0 1 1 1 0 SPX domain PAT1 PF09770.4 CDI74033.1 - 0.42 8.8 34.1 0.47 8.6 23.6 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Neur_chan_memb PF02932.11 CDI74033.1 - 0.46 10.3 17.7 0.58 10.0 12.3 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region PLRV_ORF5 PF01690.12 CDI74033.1 - 1 8.4 25.2 1.3 8.0 17.4 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein DUF4647 PF15504.1 CDI74033.1 - 2.3 6.9 26.0 3 6.6 18.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4647) Daxx PF03344.10 CDI74033.1 - 2.3 6.5 25.6 2.8 6.3 17.8 1.0 1 0 0 1 1 1 0 Daxx Family HlyD_2 PF12700.2 CDI74033.1 - 3.7 6.6 20.3 3.7 6.5 14.1 1.1 1 0 0 1 1 1 0 HlyD family secretion protein DUF2217 PF10265.4 CDI74033.1 - 4 6.0 24.9 5.2 5.7 17.3 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) SLD3 PF08639.5 CDI74033.1 - 4 5.9 42.3 4.9 5.6 29.3 1.0 1 0 0 1 1 1 0 DNA replication regulator SLD3 Utp14 PF04615.8 CDI74033.1 - 4.6 5.2 34.2 5.3 5.0 23.7 1.0 1 0 0 1 1 1 0 Utp14 protein Macoilin PF09726.4 CDI74033.1 - 4.8 5.3 39.3 6.7 4.8 27.3 1.1 1 0 0 1 1 1 0 Transmembrane protein Hid1 PF12722.2 CDI74033.1 - 4.8 4.7 33.2 5.8 4.4 23.0 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Plasmodium_Vir PF05795.6 CDI74033.1 - 5 6.2 17.9 6.6 5.8 12.4 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Ndc1_Nup PF09531.5 CDI74033.1 - 5.3 5.3 24.9 5.7 5.2 17.3 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Herpes_env PF01673.13 CDI74033.1 - 6.6 5.1 22.3 8.6 4.7 15.5 1.1 1 0 0 1 1 1 0 Herpesvirus putative major envelope glycoprotein SRP-alpha_N PF04086.8 CDI74033.1 - 6.9 5.9 33.1 8.8 5.6 23.0 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal YjgP_YjgQ PF03739.9 CDI74033.1 - 8.3 5.0 6.2 9.5 4.8 4.3 1.2 1 0 0 1 1 1 0 Predicted permease YjgP/YjgQ family zf-DHHC PF01529.15 CDI74036.1 - 0.83 9.0 4.1 3.1 7.1 0.4 2.5 2 0 0 2 2 2 0 DHHC palmitoyltransferase Tau95 PF09734.4 CDI74036.1 - 2.9 7.1 8.5 8.7 5.5 0.2 2.2 2 0 0 2 2 2 0 RNA polymerase III transcription factor (TF)IIIC subunit eIF-3_zeta PF05091.7 CDI74037.1 - 1.9 6.9 33.9 2.8 6.4 23.5 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) PAT1 PF09770.4 CDI74037.1 - 8.1 4.5 71.5 4.6 5.3 45.6 2.2 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 Pex14_N PF04695.8 CDI74038.1 - 0.0089 16.0 9.8 0.0089 16.0 6.8 13.5 7 5 3 11 11 11 2 Peroxisomal membrane anchor protein (Pex14p) conserved region IncA PF04156.9 CDI74039.1 - 0.00055 19.5 9.7 0.00055 19.5 6.7 5.6 6 1 0 6 6 6 1 IncA protein FimP PF09766.4 CDI74039.1 - 0.0032 16.5 5.4 0.0032 16.5 3.8 3.0 3 0 0 3 3 3 1 Fms-interacting protein Spt20 PF12090.3 CDI74039.1 - 0.0035 16.7 1.1 0.0035 16.7 0.7 3.2 3 0 0 3 3 3 2 Spt20 family Glt_symporter PF03616.9 CDI74039.1 - 0.015 13.7 0.5 0.015 13.7 0.3 2.7 2 0 0 2 2 2 0 Sodium/glutamate symporter HNOBA PF07701.9 CDI74039.1 - 0.034 13.3 0.2 0.034 13.3 0.1 2.8 3 0 0 3 3 3 0 Heme NO binding associated BRF1 PF07741.8 CDI74039.1 - 0.056 13.6 0.4 0.056 13.6 0.3 7.2 3 2 1 4 4 4 0 Brf1-like TBP-binding domain Suc_Fer-like PF06999.7 CDI74039.1 - 0.059 13.3 0.1 0.059 13.3 0.1 2.7 2 0 0 2 2 2 0 Sucrase/ferredoxin-like zf-DHHC PF01529.15 CDI74039.1 - 0.064 12.6 6.9 0.65 9.3 0.0 2.6 3 0 0 3 3 3 0 DHHC palmitoyltransferase Serinc PF03348.10 CDI74039.1 - 0.21 10.2 17.8 0.56 8.8 1.0 2.6 2 0 0 2 2 2 0 Serine incorporator (Serinc) CD20 PF04103.10 CDI74039.1 - 8.3 6.3 15.0 1.5 8.7 0.2 3.5 3 0 0 3 3 3 0 CD20-like family SAPS PF04499.10 CDI74040.1 - 1.1 7.8 7.4 1.8 7.1 5.1 1.7 1 1 0 1 1 1 0 SIT4 phosphatase-associated protein Spt20 PF12090.3 CDI74040.1 - 2.5 7.4 8.3 4.4 6.6 1.4 2.3 2 0 0 2 2 2 0 Spt20 family WBP-1 PF11669.3 CDI74040.1 - 4 7.5 5.5 21 5.2 0.4 2.7 2 0 0 2 2 2 0 WW domain-binding protein 1 Hid1 PF12722.2 CDI74040.1 - 4.7 4.7 6.3 8.4 3.9 4.3 1.3 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein KLRAQ PF10205.4 CDI74041.1 - 0.0058 16.6 4.7 0.012 15.6 3.3 1.5 1 0 0 1 1 1 1 Predicted coiled-coil domain-containing protein MutL PF13941.1 CDI74041.1 - 0.096 10.9 0.2 0.14 10.4 0.2 1.2 1 0 0 1 1 1 0 MutL protein PepSY_2 PF13670.1 CDI74041.1 - 0.62 10.0 3.1 30 4.6 0.0 2.7 2 0 0 2 2 2 0 Peptidase propeptide and YPEB domain DUF755 PF05501.6 CDI74043.1 - 0.0012 18.8 27.8 0.0012 18.8 19.3 5.2 4 1 1 5 5 5 1 Domain of unknown function (DUF755) UPF0139 PF03669.8 CDI74044.1 - 0.00019 20.8 0.0 0.00023 20.6 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0139) Mito_carr PF00153.22 CDI74045.1 - 2.1e-28 97.8 0.1 8.9e-15 54.1 0.0 5.6 4 2 0 4 4 4 3 Mitochondrial carrier protein Pex14_N PF04695.8 CDI74045.1 - 0.0016 18.4 31.4 0.072 13.1 0.0 4.4 4 1 0 4 4 4 3 Peroxisomal membrane anchor protein (Pex14p) conserved region Ribosomal_60s PF00428.14 CDI74045.1 - 0.49 10.8 7.8 0.31 11.4 3.4 2.1 2 0 0 2 2 2 0 60s Acidic ribosomal protein Plasmodium_Vir PF05795.6 CDI74045.1 - 4.5 6.3 12.8 0.14 11.3 2.3 2.4 2 1 0 2 2 2 0 Plasmodium vivax Vir protein Draxin PF15550.1 CDI74045.1 - 4.6 6.8 11.4 9.6 5.7 7.9 1.5 1 0 0 1 1 1 0 Draxin DUF3249 PF11615.3 CDI74047.1 - 0.055 13.2 0.1 0.19 11.5 0.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3249) zf-CCCH PF00642.19 CDI74048.1 - 4e-09 35.9 18.3 9.3e-05 22.0 0.5 3.5 3 0 0 3 3 3 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3H1 PF10650.4 CDI74048.1 - 0.013 15.0 1.7 0.013 15.0 1.2 2.3 2 0 0 2 2 2 0 Putative zinc-finger domain Gly-zipper_OmpA PF13436.1 CDI74048.1 - 5.7 6.6 25.1 0.074 12.7 4.1 2.5 2 0 0 2 2 2 0 Glycine-zipper containing OmpA-like membrane domain PsbQ PF05757.6 CDI74049.1 - 0.22 10.9 6.0 0.29 10.5 4.1 1.1 1 0 0 1 1 1 0 Oxygen evolving enhancer protein 3 (PsbQ) Med15 PF09606.5 CDI74049.1 - 2.5 6.2 17.4 3.1 5.8 12.0 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal YebO PF13974.1 CDI74049.1 - 2.9 7.7 9.1 5.5 6.8 6.3 1.4 1 0 0 1 1 1 0 YebO-like protein DUF588 PF04535.7 CDI74049.1 - 3.9 7.0 11.0 6 6.4 7.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF588) CALCOCO1 PF07888.6 CDI74050.1 - 4.5e-05 21.9 6.2 4.5e-05 21.9 4.3 5.8 3 1 2 5 5 5 1 Calcium binding and coiled-coil domain (CALCOCO1) like IncA PF04156.9 CDI74050.1 - 0.00024 20.7 14.7 0.00024 20.7 10.2 8.9 2 1 5 8 8 8 3 IncA protein Reo_sigmaC PF04582.7 CDI74050.1 - 0.24 10.5 44.1 0.02 14.0 1.5 6.2 4 2 3 7 7 7 0 Reovirus sigma C capsid protein MFMR PF07777.6 CDI74053.1 - 0.12 12.3 11.5 0.13 12.2 7.9 1.0 1 0 0 1 1 1 0 G-box binding protein MFMR DDRGK PF09756.4 CDI74053.1 - 3.2 7.1 29.6 3.4 7.0 20.5 1.0 1 0 0 1 1 1 0 DDRGK domain DUF3807 PF12720.2 CDI74053.1 - 4.4 7.4 23.9 4.8 7.3 16.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) Vfa1 PF08432.5 CDI74053.1 - 7.8 6.4 24.1 8.5 6.3 16.7 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 PRP1_N PF06424.7 CDI74055.1 - 0.00023 21.4 3.4 0.00023 21.4 2.4 5.0 4 1 0 4 4 4 1 PRP1 splicing factor, N-terminal YfhO PF09586.5 CDI74055.1 - 0.001 17.2 3.1 0.001 17.2 2.2 3.8 2 1 2 4 4 4 1 Bacterial membrane protein YfhO Nha1_C PF08619.5 CDI74055.1 - 0.001 18.4 3.3 0.001 18.4 2.3 5.0 4 1 1 5 5 5 1 Alkali metal cation/H+ antiporter Nha1 C terminus Trypan_glycop_C PF10659.4 CDI74055.1 - 0.015 15.5 8.6 0.015 15.5 6.0 6.7 6 1 1 7 7 7 0 Trypanosome variant surface glycoprotein C-terminal domain DUF1510 PF07423.6 CDI74055.1 - 0.04 13.2 0.2 0.04 13.2 0.2 4.6 4 1 0 5 5 5 0 Protein of unknown function (DUF1510) NfeD PF01957.13 CDI74056.1 - 0.23 11.5 0.9 6.7 6.8 0.1 2.4 2 0 0 2 2 2 0 NfeD-like C-terminal, partner-binding LMBR1 PF04791.11 CDI74056.1 - 0.92 8.0 2.4 71 1.7 0.0 2.9 1 1 1 2 2 2 0 LMBR1-like membrane protein Med15 PF09606.5 CDI74058.1 - 8.9e-06 24.2 70.2 8.9e-06 24.2 48.7 3.0 3 0 0 3 3 3 1 ARC105 or Med15 subunit of Mediator complex non-fungal eIF-3_zeta PF05091.7 CDI74058.1 - 0.0012 17.6 20.5 0.0012 17.6 14.2 1.9 3 0 0 3 3 3 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) IncA PF04156.9 CDI74058.1 - 0.0034 17.0 2.8 0.0034 17.0 2.0 4.7 4 1 0 4 4 2 1 IncA protein Ycf1 PF05758.7 CDI74058.1 - 0.011 13.4 15.6 0.017 12.8 10.8 1.2 1 0 0 1 1 1 0 Ycf1 GAGA_bind PF06217.7 CDI74058.1 - 0.012 15.5 16.1 0.012 15.5 11.2 1.6 2 0 0 2 2 1 0 GAGA binding protein-like family CDC45 PF02724.9 CDI74058.1 - 0.023 12.7 16.5 0.0055 14.8 9.3 1.4 2 0 0 2 2 2 0 CDC45-like protein DUF605 PF04652.11 CDI74058.1 - 0.039 13.3 30.9 0.021 14.2 18.9 2.2 2 0 0 2 2 2 0 Vta1 like Hid1 PF12722.2 CDI74058.1 - 0.064 10.9 22.6 0.094 10.3 15.7 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein 7tm_1 PF00001.16 CDI74058.1 - 0.066 12.3 5.7 29 3.7 4.0 3.1 1 1 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) Anoctamin PF04547.7 CDI74058.1 - 0.22 10.1 15.3 0.48 9.0 10.6 1.5 1 0 0 1 1 1 0 Calcium-activated chloride channel DDHD PF02862.12 CDI74058.1 - 0.3 10.8 23.4 0.13 12.0 14.1 2.0 3 0 0 3 3 2 0 DDHD domain AUX_IAA PF02309.11 CDI74058.1 - 0.38 10.4 20.8 0.14 11.9 12.4 1.7 2 0 0 2 2 1 0 AUX/IAA family Neur_chan_memb PF02932.11 CDI74058.1 - 0.43 10.4 19.6 1.5 8.6 13.0 2.1 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Spore_coat_CotO PF14153.1 CDI74058.1 - 0.63 9.4 36.1 0.073 12.5 20.9 2.1 2 0 0 2 2 2 0 Spore coat protein CotO HCO3_cotransp PF00955.16 CDI74058.1 - 0.73 8.4 8.3 1.2 7.6 5.8 1.3 1 0 0 1 1 1 0 HCO3- transporter family PBP1_TM PF14812.1 CDI74058.1 - 0.88 9.9 18.1 0.031 14.5 7.9 2.1 2 1 1 3 3 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF912 PF06024.7 CDI74058.1 - 1.1 9.3 26.0 0.032 14.2 4.6 3.8 2 2 1 3 3 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) RR_TM4-6 PF06459.7 CDI74058.1 - 1.1 9.0 23.6 0.03 14.2 11.5 1.9 2 0 0 2 2 1 0 Ryanodine Receptor TM 4-6 Membralin PF09746.4 CDI74058.1 - 1.8 7.5 7.2 2.6 7.0 5.0 1.2 1 0 0 1 1 1 0 Tumour-associated protein DUF4011 PF13195.1 CDI74058.1 - 1.8 8.5 13.9 1.7 8.6 8.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4011) Spore_YhcN_YlaJ PF09580.5 CDI74058.1 - 1.8 8.6 25.0 27 4.8 15.4 2.5 2 0 0 2 2 2 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) Band_3_cyto PF07565.8 CDI74058.1 - 1.9 7.9 25.1 0.33 10.4 14.4 2.0 2 0 0 2 2 2 0 Band 3 cytoplasmic domain LMBR1 PF04791.11 CDI74058.1 - 2.6 6.5 10.8 4.2 5.8 7.5 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF4045 PF13254.1 CDI74058.1 - 2.6 7.2 22.2 5.9 6.0 15.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Plasmodium_Vir PF05795.6 CDI74058.1 - 3.3 6.8 5.7 5.2 6.1 4.0 1.3 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Nucleoside_tran PF01733.13 CDI74058.1 - 4.3 6.3 10.6 1.4 8.0 5.0 1.9 2 0 0 2 2 2 0 Nucleoside transporter SID-1_RNA_chan PF13965.1 CDI74058.1 - 4.9 5.1 14.9 8.9 4.3 10.4 1.4 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Tim54 PF11711.3 CDI74058.1 - 5.9 5.3 15.8 0.57 8.7 7.9 1.5 2 0 0 2 2 1 0 Inner membrane protein import complex subunit Tim54 G-alpha PF00503.15 CDI74058.1 - 6.3 5.3 20.3 16 4.0 14.1 1.8 1 0 0 1 1 1 0 G-protein alpha subunit YjgP_YjgQ PF03739.9 CDI74058.1 - 6.6 5.3 13.0 12 4.4 9.0 1.5 1 0 0 1 1 1 0 Predicted permease YjgP/YjgQ family Dicty_REP PF05086.7 CDI74058.1 - 7.4 4.1 13.0 9.5 3.8 9.0 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein FAM91_C PF14648.1 CDI74058.1 - 8.4 5.1 15.5 18 4.0 10.8 1.4 1 0 0 1 1 1 0 FAM91 C-terminus FLO_LFY PF01698.11 CDI74058.1 - 9 5.0 25.2 2.4 6.9 15.3 1.5 2 0 0 2 2 2 0 Floricaula / Leafy protein Y_phosphatase3 PF13350.1 CDI74058.1 - 9.8 6.3 10.4 27 4.9 7.2 1.8 1 0 0 1 1 1 0 Tyrosine phosphatase family Roughex PF06020.6 CDI74059.1 - 9.9e-05 21.1 13.8 0.00013 20.7 9.5 1.1 1 0 0 1 1 1 1 Drosophila roughex protein Trypan_PARP PF05887.6 CDI74059.1 - 0.0014 18.4 24.6 0.0014 18.4 17.1 1.9 2 0 0 2 2 2 1 Procyclic acidic repetitive protein (PARP) DUF1510 PF07423.6 CDI74059.1 - 0.29 10.4 35.4 0.067 12.5 20.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) DUF4407 PF14362.1 CDI74059.1 - 0.78 8.6 14.0 1.1 8.1 9.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) V_ATPase_I PF01496.14 CDI74059.1 - 1.2 6.8 8.0 1.6 6.5 5.5 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Hid1 PF12722.2 CDI74059.1 - 1.8 6.1 17.0 2.2 5.8 11.8 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Nop25 PF09805.4 CDI74059.1 - 2.1 8.4 32.8 0.7 9.9 17.9 2.2 2 0 0 2 2 2 0 Nucleolar protein 12 (25kDa) Pilt PF15453.1 CDI74059.1 - 2.2 7.9 27.0 3.3 7.2 18.7 1.2 1 0 0 1 1 1 0 Protein incorporated later into Tight Junctions VESA1_N PF12785.2 CDI74059.1 - 2.2 7.1 16.0 2.8 6.8 11.1 1.2 1 0 0 1 1 1 0 Variant erythrocyte surface antigen-1 BUD22 PF09073.5 CDI74059.1 - 2.5 7.0 29.2 3.7 6.5 20.2 1.2 1 0 0 1 1 1 0 BUD22 Tim54 PF11711.3 CDI74059.1 - 2.8 6.4 21.0 0.069 11.7 9.5 1.9 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 DUF936 PF06075.7 CDI74059.1 - 2.9 6.7 16.9 3.1 6.5 11.7 1.0 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) DUF3504 PF12012.3 CDI74059.1 - 3.2 7.5 16.7 2.3 7.9 1.8 2.6 1 1 2 3 3 3 0 Domain of unknown function (DUF3504) CT47 PF15623.1 CDI74059.1 - 3.7 7.1 42.3 0.04 13.6 23.3 1.8 2 0 0 2 2 2 0 Cancer/testis gene family 47 FTCD_C PF04961.7 CDI74059.1 - 4.3 6.7 15.0 9.4 5.6 10.4 1.6 1 0 0 1 1 1 0 Formiminotransferase-cyclodeaminase Na_trans_assoc PF06512.8 CDI74059.1 - 4.8 7.0 23.9 7.4 6.4 16.5 1.4 1 0 0 1 1 1 0 Sodium ion transport-associated GAGA_bind PF06217.7 CDI74059.1 - 4.9 7.0 13.2 6.2 6.7 9.1 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family Mnd1 PF03962.10 CDI74059.1 - 9.2 5.8 19.2 6.6 6.3 10.2 2.1 2 0 0 2 2 2 0 Mnd1 family Parvo_coat PF00740.13 CDI74059.1 - 9.5 5.0 11.8 12 4.6 8.2 1.1 1 0 0 1 1 1 0 Parvovirus coat protein VP2 DUF3807 PF12720.2 CDI74060.1 - 1.9 8.6 27.6 2.3 8.3 19.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) DUF1510 PF07423.6 CDI74060.1 - 3.1 7.1 23.9 3.6 6.8 16.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DUF2052 PF09747.4 CDI74060.1 - 6.1 6.7 30.9 8.1 6.3 21.4 1.1 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) FAM60A PF15396.1 CDI74060.1 - 6.3 6.4 21.7 7 6.3 15.1 1.0 1 0 0 1 1 1 0 Protein Family FAM60A APG6 PF04111.7 CDI74063.1 - 0.0047 16.0 7.0 0.0047 16.0 4.8 2.7 2 1 0 2 2 2 1 Autophagy protein Apg6 MFS_1 PF07690.11 CDI74064.1 - 1.6e-33 115.8 32.5 2.2e-29 102.2 14.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 CDI74064.1 - 1.6e-06 26.9 14.7 7e-06 24.8 6.4 2.4 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1_like PF12832.2 CDI74064.1 - 0.0027 17.4 0.0 0.24 11.2 0.0 2.9 2 0 0 2 2 2 1 MFS_1 like family ATG22 PF11700.3 CDI74064.1 - 0.0065 15.0 19.7 0.18 10.2 5.8 2.3 1 1 1 2 2 2 2 Vacuole effluxer Atg22 like DnaJ PF00226.26 CDI74065.1 - 6.9e-27 92.9 0.6 1.1e-26 92.3 0.4 1.3 1 0 0 1 1 1 1 DnaJ domain DUF4647 PF15504.1 CDI74066.1 - 0.023 13.5 32.8 0.037 12.8 19.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4647) Hid1 PF12722.2 CDI74066.1 - 1.3 6.6 28.7 1.5 6.3 19.9 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Ndc1_Nup PF09531.5 CDI74066.1 - 3.4 5.9 20.9 3.9 5.7 14.5 1.4 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Herpes_DNAp_acc PF04929.7 CDI74066.1 - 5.5 5.8 21.8 5 5.9 14.3 1.5 1 1 0 1 1 1 0 Herpes DNA replication accessory factor CAF-1_p150 PF11600.3 CDI74067.1 - 0.44 9.8 69.8 0.023 14.1 23.7 2.9 2 1 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal SAGA-Tad1 PF12767.2 CDI74067.1 - 3.4 7.2 68.4 1.1 8.9 14.0 2.7 2 0 0 2 2 2 0 Transcriptional regulator of RNA polII, SAGA, subunit BPD_transp_2 PF02653.11 CDI74068.1 - 0.012 14.6 0.2 0.017 14.1 0.1 1.2 1 0 0 1 1 1 0 Branched-chain amino acid transport system / permease component CDC27 PF09507.5 CDI74068.1 - 2.3 7.3 57.1 3.3 6.8 39.6 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 DUF3123 PF11321.3 CDI74068.1 - 2.5 8.3 12.2 6.5 7.0 8.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3123) Activator_LAG-3 PF11498.3 CDI74069.1 - 2.2e-06 26.7 23.3 2.2e-06 26.7 16.1 13.5 11 3 2 14 14 14 1 Transcriptional activator LAG-3 PQQ PF01011.16 CDI74069.1 - 0.034 13.6 0.9 1.1 8.8 0.0 2.6 2 0 0 2 2 2 0 PQQ enzyme repeat Herpes_DNAp_acc PF04929.7 CDI74069.1 - 7.9 5.3 0.0 7.9 5.3 0.0 10.8 9 3 2 11 11 11 0 Herpes DNA replication accessory factor RAP PF08373.5 CDI74071.1 - 4.6e-09 35.9 0.0 7.6e-09 35.2 0.0 1.3 1 0 0 1 1 1 1 RAP domain AAA_13 PF13166.1 CDI74072.1 - 1.2 7.5 2.4 1.9 6.8 1.6 1.2 1 0 0 1 1 1 0 AAA domain Kinesin PF00225.18 CDI74073.1 - 6.1e-97 324.3 2.8 8.3e-65 218.6 0.2 2.1 1 1 1 2 2 2 2 Kinesin motor domain AAA_22 PF13401.1 CDI74073.1 - 0.0071 16.4 0.2 0.39 10.8 0.0 3.1 3 1 1 4 4 4 1 AAA domain LIM_bind PF01803.11 CDI74073.1 - 0.046 12.8 1.0 2.5 7.1 0.0 2.9 3 0 0 3 3 3 0 LIM-domain binding protein FCP1_C PF09309.5 CDI74074.1 - 0.00062 19.1 7.6 0.00081 18.7 5.3 1.1 1 0 0 1 1 1 1 FCP1, C-terminal Bindin PF02084.10 CDI74074.1 - 0.003 17.6 10.2 0.0037 17.3 7.1 1.1 1 0 0 1 1 1 1 Bindin Med15 PF09606.5 CDI74074.1 - 0.018 13.2 21.0 0.02 13.1 14.5 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Spp-24 PF07448.6 CDI74074.1 - 0.067 13.1 2.7 0.11 12.5 1.9 1.3 1 0 0 1 1 1 0 Secreted phosphoprotein 24 (Spp-24) NARP1 PF12569.3 CDI74074.1 - 0.26 9.9 4.0 0.38 9.4 2.8 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Plasmodium_Vir PF05795.6 CDI74074.1 - 0.33 10.1 2.6 0.4 9.8 1.8 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Neur_chan_memb PF02932.11 CDI74074.1 - 0.48 10.2 5.5 0.57 10.0 3.8 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region eIF-3_zeta PF05091.7 CDI74074.1 - 0.95 8.0 6.8 1 7.9 4.7 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) GRP PF07172.6 CDI74074.1 - 2.5 8.6 8.7 4.1 7.9 6.0 1.3 1 0 0 1 1 1 0 Glycine rich protein family Spt20 PF12090.3 CDI74074.1 - 2.8 7.2 12.5 7.8 5.7 7.6 1.9 2 0 0 2 2 2 0 Spt20 family Hid1 PF12722.2 CDI74074.1 - 3.5 5.1 7.7 4.1 4.9 5.3 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF4175 PF13779.1 CDI74074.1 - 4.2 4.9 22.8 4.9 4.7 15.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) DivIC PF04977.10 CDI74074.1 - 5.6 6.5 14.2 10 5.6 9.8 1.4 1 0 0 1 1 1 0 Septum formation initiator Macoilin PF09726.4 CDI74074.1 - 6 5.0 11.5 7.8 4.6 7.9 1.1 1 0 0 1 1 1 0 Transmembrane protein FimP PF09766.4 CDI74074.1 - 8.4 5.3 14.2 11 4.9 9.8 1.1 1 0 0 1 1 1 0 Fms-interacting protein ATAD4 PF15321.1 CDI74074.1 - 9.5 7.3 9.8 13 6.8 3.9 2.1 2 0 0 2 2 2 0 ATPase family AAA domain containing 4 Cir_N PF10197.4 CDI74075.1 - 2.9e-12 46.3 9.7 2.9e-12 46.3 6.7 3.9 4 1 0 4 4 4 1 N-terminal domain of CBF1 interacting co-repressor CIR APG6 PF04111.7 CDI74075.1 - 4 6.3 16.6 0.22 10.5 6.5 2.0 2 0 0 2 2 2 0 Autophagy protein Apg6 DEAD PF00270.24 CDI74076.1 - 7.1e-27 93.9 0.0 2.1e-25 89.1 0.0 3.0 2 2 1 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CDI74076.1 - 1e-16 60.5 0.0 2.3e-16 59.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain EF-hand_6 PF13405.1 CDI74077.1 - 2e-10 39.6 0.0 0.00033 20.2 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.27 CDI74077.1 - 3.4e-10 38.4 0.0 0.00061 18.9 0.0 2.6 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.1 CDI74077.1 - 1.7e-09 37.6 0.0 0.00046 20.2 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 CDI74077.1 - 1.6e-05 24.3 0.0 0.0078 15.8 0.0 2.8 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_9 PF14658.1 CDI74077.1 - 2.2e-05 24.2 0.1 0.21 11.4 0.0 3.0 3 1 0 3 3 3 2 EF-hand domain EF-hand_5 PF13202.1 CDI74077.1 - 0.011 15.0 0.0 1.2 8.6 0.0 2.6 2 0 0 2 2 2 0 EF hand BRCT PF00533.21 CDI74078.1 - 0.14 12.2 1.0 6 7.0 0.0 3.5 3 2 0 3 3 3 0 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 CDI74078.1 - 0.17 11.7 0.0 54 3.7 0.0 3.2 3 0 0 3 3 3 0 twin BRCT domain GTP_EFTU_D2 PF03144.20 CDI74082.1 - 0.0046 17.0 0.0 0.096 12.8 0.0 2.6 1 1 1 2 2 2 1 Elongation factor Tu domain 2 EFG_II PF14492.1 CDI74082.1 - 0.0054 16.5 0.0 0.0098 15.7 0.0 1.4 1 0 0 1 1 1 1 Elongation Factor G, domain II DUF2510 PF10708.4 CDI74082.1 - 0.032 13.6 1.3 0.032 13.6 0.9 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2510) EFG_C PF00679.19 CDI74082.1 - 0.036 13.9 0.0 0.062 13.1 0.0 1.4 1 0 0 1 1 1 0 Elongation factor G C-terminus MelC1 PF06236.6 CDI74082.1 - 3.1 7.7 17.7 1.5 8.7 4.6 2.2 2 0 0 2 2 2 0 Tyrosinase co-factor MelC1 Med15 PF09606.5 CDI74083.1 - 0.00068 17.9 43.2 0.00068 17.9 29.9 1.1 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal Trypan_PARP PF05887.6 CDI74083.1 - 4.3 7.1 96.8 14 5.4 21.7 3.2 1 1 2 3 3 3 0 Procyclic acidic repetitive protein (PARP) Metallophos PF00149.23 CDI74085.1 - 4.9e-35 120.7 0.1 7e-35 120.2 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase TPR_11 PF13414.1 CDI74085.1 - 1.1e-18 66.6 6.0 8.7e-15 54.1 0.5 2.5 2 0 0 2 2 2 2 TPR repeat PPP5 PF08321.7 CDI74085.1 - 8.1e-15 54.6 0.0 2.2e-14 53.2 0.0 1.8 1 0 0 1 1 1 1 PPP5 TPR repeat region TPR_2 PF07719.12 CDI74085.1 - 9.7e-15 53.2 4.2 0.00063 19.4 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.23 CDI74085.1 - 1.6e-11 43.3 3.8 0.011 15.3 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_14 PF13428.1 CDI74085.1 - 0.0011 19.4 2.5 4.1 8.3 0.0 3.9 2 1 2 4 4 3 1 Tetratricopeptide repeat TPR_17 PF13431.1 CDI74085.1 - 0.0018 18.3 0.1 0.009 16.1 0.0 2.3 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_12 PF13424.1 CDI74085.1 - 0.0029 17.5 2.4 0.05 13.5 0.1 2.7 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.1 CDI74085.1 - 0.0029 17.4 0.2 0.011 15.5 0.0 1.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 CDI74085.1 - 0.081 13.6 6.2 7.3 7.4 0.0 3.5 2 1 1 3 3 3 0 Tetratricopeptide repeat bPH_4 PF06713.6 CDI74085.1 - 0.089 12.6 0.0 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 Bacterial PH domain Zip PF02535.17 CDI74086.1 - 0.28 10.1 4.3 0.36 9.7 2.9 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter SelP_N PF04592.9 CDI74086.1 - 1.6 8.0 11.7 3.6 6.9 8.1 1.5 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Herpes_DNAp_acc PF04929.7 CDI74086.1 - 2.6 6.9 9.0 4.4 6.1 6.3 1.3 1 0 0 1 1 1 0 Herpes DNA replication accessory factor DUF1387 PF07139.6 CDI74086.1 - 2.9 7.4 9.8 5.5 6.5 6.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) PAT1 PF09770.4 CDI74086.1 - 5.6 5.0 29.9 7.4 4.6 20.7 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 tRNA-synt_2 PF00152.15 CDI74087.1 - 2.3e-11 43.0 0.1 3.2e-11 42.5 0.1 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) Spt20 PF12090.3 CDI74087.1 - 0.0092 15.3 2.3 0.0092 15.3 1.6 2.8 2 1 0 2 2 1 1 Spt20 family CDK2AP PF09806.4 CDI74087.1 - 0.021 15.0 10.8 0.021 15.0 7.5 4.4 2 1 1 3 3 1 0 Cyclin-dependent kinase 2-associated protein DUF3801 PF12687.2 CDI74087.1 - 0.067 12.7 0.1 0.067 12.7 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3801) U1snRNP70_N PF12220.3 CDI74087.1 - 0.5 10.7 14.3 0.22 11.8 4.2 2.4 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal DUF4570 PF15134.1 CDI74087.1 - 0.65 9.8 18.9 0.58 10.0 5.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4570) PAP1 PF08601.5 CDI74087.1 - 1.1 8.8 22.8 5.7 6.5 11.2 2.2 2 0 0 2 2 2 0 Transcription factor PAP1 FAM60A PF15396.1 CDI74087.1 - 2.2 7.9 14.4 5.7 6.6 0.5 2.2 2 0 0 2 2 2 0 Protein Family FAM60A DUF572 PF04502.8 CDI74087.1 - 2.8 7.0 20.1 1.8 7.7 8.0 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF572) Neur_chan_memb PF02932.11 CDI74087.1 - 3.1 7.6 9.9 18 5.1 3.9 2.1 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Rsc14 PF08586.5 CDI74087.1 - 4.5 7.7 11.5 0.13 12.7 1.2 2.4 2 1 0 2 2 2 0 RSC complex, Rsc14/Ldb7 subunit DUF1645 PF07816.6 CDI74087.1 - 4.6 7.6 16.9 0.029 14.8 3.5 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1645) dsDNA_bind PF01984.15 CDI74087.1 - 5.8 6.9 29.2 0.57 10.2 8.4 2.5 2 0 0 2 2 2 0 Double-stranded DNA-binding domain Band_3_cyto PF07565.8 CDI74087.1 - 8.5 5.7 14.4 1.5 8.2 0.3 2.2 2 0 0 2 2 2 0 Band 3 cytoplasmic domain NARP1 PF12569.3 CDI74088.1 - 1.2 7.7 30.2 1.4 7.5 20.9 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DUF1510 PF07423.6 CDI74088.1 - 1.3 8.2 32.5 1.4 8.2 22.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DUF1168 PF06658.7 CDI74088.1 - 6.7 6.2 37.5 7.2 6.1 26.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) SprA-related PF12118.3 CDI74089.1 - 0.0038 16.5 34.5 0.0038 16.5 23.9 4.4 3 2 0 3 3 3 1 SprA-related family BAF1_ABF1 PF04684.8 CDI74089.1 - 0.0057 15.5 21.0 0.0057 15.5 14.6 6.7 2 2 4 6 6 6 1 BAF1 / ABF1 chromatin reorganising factor HATPase_c_5 PF14501.1 CDI74089.1 - 0.0081 15.8 0.0 0.034 13.8 0.0 2.0 1 0 0 1 1 1 1 GHKL domain Clathrin_lg_ch PF01086.12 CDI74090.1 - 3.9e-08 33.4 37.2 1.6e-07 31.5 25.7 2.0 1 1 0 1 1 1 1 Clathrin light chain PLRV_ORF5 PF01690.12 CDI74090.1 - 0.35 9.9 28.6 0.42 9.6 19.8 1.0 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein PAT1 PF09770.4 CDI74090.1 - 0.62 8.2 54.8 0.81 7.8 38.0 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 FYVE PF01363.16 CDI74091.1 - 2.8e-16 59.1 11.1 2.8e-16 59.1 7.7 3.3 3 0 0 3 3 3 1 FYVE zinc finger IncA PF04156.9 CDI74091.1 - 0.00027 20.6 4.0 0.00027 20.6 2.7 8.7 7 3 1 8 8 8 2 IncA protein Spt20 PF12090.3 CDI74091.1 - 0.94 8.7 39.6 0.13 11.6 2.7 5.1 5 0 0 5 5 5 0 Spt20 family E_Pc_C PF06752.7 CDI74092.1 - 0.00017 21.1 20.4 0.00017 21.1 14.1 27.5 18 5 6 25 25 25 1 Enhancer of Polycomb C-terminus SHR3_chaperone PF08229.6 CDI74093.1 - 1.3 7.8 7.1 2.2 7.1 4.9 1.4 1 0 0 1 1 1 0 ER membrane protein SH3 DUF788 PF05620.6 CDI74093.1 - 5.1 6.9 10.1 15 5.3 7.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF788) 2OG-FeII_Oxy PF03171.15 CDI74095.1 - 0.015 15.5 0.0 0.15 12.3 0.0 2.3 1 1 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Penaeidin PF05927.6 CDI74095.1 - 2 9.0 5.8 34 5.0 0.1 3.2 3 0 0 3 3 3 0 Penaeidin Arf PF00025.16 CDI74097.1 - 2.2e-30 105.1 0.0 2.8e-30 104.8 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 CDI74097.1 - 6.8e-05 22.3 0.0 8.7e-05 21.9 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.5 CDI74097.1 - 0.00046 19.4 0.0 0.0049 16.0 0.0 2.0 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Miro PF08477.8 CDI74097.1 - 0.0027 18.2 0.0 0.005 17.3 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein GTP_EFTU PF00009.22 CDI74097.1 - 0.0032 16.9 0.0 0.064 12.6 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Band_7 PF01145.20 CDI74098.1 - 4.4e-27 95.1 0.7 5.6e-27 94.7 0.0 1.4 2 0 0 2 2 2 1 SPFH domain / Band 7 family Band_7_1 PF13421.1 CDI74098.1 - 0.015 14.8 0.0 0.049 13.1 0.0 1.8 1 1 1 2 2 2 0 SPFH domain-Band 7 family CDC27 PF09507.5 CDI74100.1 - 1.5 7.9 64.9 0.021 14.0 38.8 1.9 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 Shadoo PF14999.1 CDI74100.1 - 3.9 7.3 15.2 1.6 8.5 7.2 2.6 2 0 0 2 2 2 0 Shadow of prion protein, neuroprotective PAT1 PF09770.4 CDI74100.1 - 6.6 4.8 65.4 10 4.2 45.4 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 CAF-1_p150 PF11600.3 CDI74101.1 - 0.00029 20.3 20.8 0.00029 20.3 14.4 17.1 10 3 5 15 15 15 5 Chromatin assembly factor 1 complex p150 subunit, N-terminal ERCC4 PF02732.10 CDI74102.1 - 5.6e-13 48.8 0.0 5.6e-13 48.8 0.0 2.6 2 1 0 2 2 2 1 ERCC4 domain Cwf_Cwc_15 PF04889.7 CDI74102.1 - 0.00035 20.3 6.1 0.00035 20.3 4.2 5.0 3 1 1 5 5 5 1 Cwf15/Cwc15 cell cycle control protein RAB3GAP2_N PF14655.1 CDI74102.1 - 0.0011 18.1 4.1 0.0011 18.1 2.8 5.5 3 1 0 3 3 3 1 Rab3 GTPase-activating protein regulatory subunit N-terminus SR-25 PF10500.4 CDI74102.1 - 0.0067 15.9 3.8 0.0067 15.9 2.6 11.3 6 4 2 8 8 8 1 Nuclear RNA-splicing-associated protein Gly-zipper_OmpA PF13436.1 CDI74103.1 - 0.93 9.1 13.3 2 8.1 9.2 1.5 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain DUF4207 PF13904.1 CDI74103.1 - 1.7 7.9 9.7 2.1 7.6 6.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4207) Cyto_ox_2 PF02322.10 CDI74103.1 - 5.5 6.0 7.8 6.1 5.9 5.4 1.1 1 0 0 1 1 1 0 Cytochrome oxidase subunit II Spc7 PF08317.6 CDI74104.1 - 0.1 11.2 51.6 0.13 10.9 35.8 1.0 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF3552 PF12072.3 CDI74104.1 - 0.45 9.7 73.8 0.11 11.7 25.6 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF3552) APG6 PF04111.7 CDI74104.1 - 1 8.3 60.9 1.5 7.8 42.2 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF972 PF06156.8 CDI74104.1 - 2.8 8.3 49.1 3 8.2 15.9 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Reo_sigmaC PF04582.7 CDI74104.1 - 8.9 5.3 11.7 12 4.9 8.1 1.2 1 0 0 1 1 1 0 Reovirus sigma C capsid protein CAF-1_p150 PF11600.3 CDI74106.1 - 0.0018 17.6 46.3 0.0018 17.6 32.1 2.0 1 1 1 2 2 2 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal BAF1_ABF1 PF04684.8 CDI74107.1 - 0.008 15.0 0.8 0.008 15.0 0.5 15.1 8 3 6 16 16 16 3 BAF1 / ABF1 chromatin reorganising factor Adaptin_binding PF10199.4 CDI74107.1 - 0.0091 16.2 0.4 0.0091 16.2 0.3 9.3 3 2 1 5 5 5 1 Alpha and gamma adaptin binding protein p34 CKAP2_C PF15297.1 CDI74108.1 - 0.039 12.7 10.1 0.04 12.7 7.0 1.0 1 0 0 1 1 1 0 Cytoskeleton-associated protein 2 C-terminus DUF2457 PF10446.4 CDI74108.1 - 0.14 10.8 29.2 0.16 10.6 20.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) SURF6 PF04935.7 CDI74108.1 - 0.16 11.1 9.4 0.18 11.0 6.5 1.0 1 0 0 1 1 1 0 Surfeit locus protein 6 TRAP_alpha PF03896.11 CDI74108.1 - 0.24 10.3 17.8 0.26 10.2 12.3 1.0 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Prog_receptor PF02161.10 CDI74108.1 - 0.26 10.0 13.3 0.29 9.9 9.2 1.0 1 0 0 1 1 1 0 Progesterone receptor DUF3306 PF11748.3 CDI74108.1 - 0.37 11.4 12.7 0.42 11.2 8.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3306) Nop25 PF09805.4 CDI74108.1 - 0.38 10.8 21.1 0.41 10.7 14.6 1.0 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) DARPP-32 PF05395.7 CDI74108.1 - 0.4 10.8 16.5 0.4 10.8 11.4 1.0 1 0 0 1 1 1 0 Protein phosphatase inhibitor 1/DARPP-32 DUF2722 PF10846.3 CDI74108.1 - 0.53 9.2 10.5 0.54 9.2 7.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Vfa1 PF08432.5 CDI74108.1 - 0.59 10.1 13.7 0.6 10.1 9.5 1.0 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF572 PF04502.8 CDI74108.1 - 0.69 9.0 14.1 0.71 9.0 9.8 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF572) Paf1 PF03985.8 CDI74108.1 - 1 8.0 26.4 1 8.0 18.3 1.0 1 0 0 1 1 1 0 Paf1 Sigma70_ner PF04546.8 CDI74108.1 - 1 8.9 22.9 1.1 8.7 15.9 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region PRP21_like_P PF12230.3 CDI74108.1 - 1.3 8.5 11.8 1.4 8.4 8.2 1.1 1 0 0 1 1 1 0 Pre-mRNA splicing factor PRP21 like protein Orbi_VP6 PF01516.11 CDI74108.1 - 1.6 7.7 14.7 1.7 7.6 10.2 1.0 1 0 0 1 1 1 0 Orbivirus helicase VP6 Pox_Ag35 PF03286.9 CDI74108.1 - 2 7.9 17.2 2.4 7.6 12.0 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Fmp27 PF10344.4 CDI74108.1 - 2 5.9 9.1 2 5.9 6.3 1.0 1 0 0 1 1 1 0 Mitochondrial protein from FMP27 Nop14 PF04147.7 CDI74108.1 - 2.1 6.1 32.1 2.3 6.0 22.2 1.0 1 0 0 1 1 1 0 Nop14-like family Tim54 PF11711.3 CDI74108.1 - 2.2 6.7 10.3 2.2 6.7 7.1 1.0 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 CDC45 PF02724.9 CDI74108.1 - 2.2 6.1 22.1 2.2 6.1 15.3 1.0 1 0 0 1 1 1 0 CDC45-like protein NARP1 PF12569.3 CDI74108.1 - 2.3 6.8 7.8 2.2 6.9 5.4 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Plasmodium_Vir PF05795.6 CDI74108.1 - 2.3 7.3 6.9 2.4 7.2 4.8 1.0 1 0 0 1 1 1 0 Plasmodium vivax Vir protein DDRGK PF09756.4 CDI74108.1 - 2.5 7.4 19.4 2.5 7.4 13.5 1.1 1 0 0 1 1 1 0 DDRGK domain DUF4045 PF13254.1 CDI74108.1 - 2.5 7.2 7.0 2.5 7.2 4.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) FYDLN_acid PF09538.5 CDI74108.1 - 2.9 8.5 20.2 3.3 8.3 14.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) Daxx PF03344.10 CDI74108.1 - 3.3 6.1 32.9 3.4 6.0 22.8 1.0 1 0 0 1 1 1 0 Daxx Family CENP-T PF15511.1 CDI74108.1 - 3.4 6.8 18.1 3.6 6.7 12.5 1.0 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T DUF1510 PF07423.6 CDI74108.1 - 3.4 6.9 22.8 3.7 6.8 15.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) SpoIIIAH PF12685.2 CDI74108.1 - 3.5 7.0 12.8 4 6.8 8.9 1.1 1 0 0 1 1 1 0 SpoIIIAH-like protein VID27 PF08553.5 CDI74108.1 - 3.8 5.6 22.2 3.9 5.5 15.4 1.0 1 0 0 1 1 1 0 VID27 cytoplasmic protein TEX19 PF15553.1 CDI74108.1 - 4.4 7.1 14.0 4.9 6.9 9.7 1.1 1 0 0 1 1 1 0 Testis-expressed protein 19 Zip PF02535.17 CDI74108.1 - 5.1 6.0 7.8 5.4 5.9 5.4 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter YqfQ PF14181.1 CDI74108.1 - 5.2 7.0 13.8 5.9 6.9 9.5 1.1 1 0 0 1 1 1 0 YqfQ-like protein SDA1 PF05285.7 CDI74108.1 - 5.7 6.1 26.9 6.1 6.0 18.6 1.0 1 0 0 1 1 1 0 SDA1 TraH_2 PF06871.6 CDI74108.1 - 5.8 6.2 6.0 6.4 6.1 4.2 1.2 1 0 0 1 1 1 0 TraH_2 XAP5 PF04921.9 CDI74108.1 - 6 6.3 12.1 7.5 6.0 8.4 1.3 1 0 0 1 1 1 0 XAP5, circadian clock regulator Trypan_PARP PF05887.6 CDI74108.1 - 6.2 6.6 24.5 6.9 6.4 17.0 1.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) CobT PF06213.7 CDI74108.1 - 6.7 5.7 31.9 7.1 5.6 22.1 1.0 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT NOA36 PF06524.7 CDI74108.1 - 7.3 5.7 18.4 9.3 5.4 12.8 1.2 1 0 0 1 1 1 0 NOA36 protein RNA_pol_Rpc4 PF05132.9 CDI74108.1 - 7.3 6.5 11.1 9.1 6.2 7.7 1.2 1 0 0 1 1 1 0 RNA polymerase III RPC4 eIF-3c_N PF05470.7 CDI74108.1 - 7.7 4.4 12.2 8.1 4.4 8.5 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Peptidase_S64 PF08192.6 CDI74108.1 - 8 4.6 6.8 7.9 4.6 4.7 1.0 1 0 0 1 1 1 0 Peptidase family S64 NPR3 PF03666.8 CDI74108.1 - 8.6 4.7 7.5 8.9 4.7 5.2 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 RR_TM4-6 PF06459.7 CDI74108.1 - 9.6 6.0 15.1 10 5.9 10.5 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Wbp11 PF09429.5 CDI74110.1 - 9.7e-18 63.9 10.1 1.5e-17 63.3 7.0 1.3 1 0 0 1 1 1 1 WW domain binding protein 11 MSC PF09402.5 CDI74110.1 - 0.091 11.4 2.2 0.1 11.2 1.2 1.4 1 1 0 1 1 1 0 Man1-Src1p-C-terminal domain RapA_C PF12137.3 CDI74110.1 - 0.16 10.7 2.5 0.21 10.4 1.7 1.2 1 0 0 1 1 1 0 RNA polymerase recycling family C-terminal DUF3490 PF11995.3 CDI74110.1 - 1.3 8.5 5.1 1.5 8.3 3.1 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF3490) Herpes_DNAp_acc PF04929.7 CDI74111.1 - 0.0037 16.2 0.0 0.0037 16.2 0.0 9.6 5 4 3 8 8 8 2 Herpes DNA replication accessory factor K_channel_TID PF07941.6 CDI74112.1 - 0.00072 19.7 7.3 0.00072 19.7 5.0 11.0 10 0 0 10 10 10 5 Potassium channel Kv1.4 tandem inactivation domain PRP38_assoc PF12871.2 CDI74113.1 - 0.0016 18.9 17.2 0.0023 18.4 11.9 1.3 1 0 0 1 1 1 1 Pre-mRNA-splicing factor 38-associated hydrophilic C-term SprA-related PF12118.3 CDI74113.1 - 0.018 14.3 27.9 0.018 14.3 19.3 1.1 1 0 0 1 1 1 0 SprA-related family Suf PF05843.9 CDI74113.1 - 0.11 12.1 19.3 0.12 12.0 13.4 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF2201_N PF13203.1 CDI74113.1 - 0.26 10.4 16.6 0.26 10.4 11.5 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain DUF1777 PF08648.7 CDI74113.1 - 0.35 10.5 36.9 0.44 10.2 25.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) RR_TM4-6 PF06459.7 CDI74113.1 - 0.76 9.6 13.8 0.91 9.3 9.6 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SOBP PF15279.1 CDI74113.1 - 1.2 9.4 13.0 1.2 9.4 9.0 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein SAGA-Tad1 PF12767.2 CDI74113.1 - 2.4 7.7 23.8 2.9 7.4 16.5 1.1 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit AAA_23 PF13476.1 CDI74113.1 - 4.4 7.5 17.0 4.8 7.4 11.8 1.2 1 0 0 1 1 1 0 AAA domain Herpes_UL87 PF03043.9 CDI74113.1 - 6.5 5.0 9.7 6.8 4.9 6.7 1.0 1 0 0 1 1 1 0 Herpesvirus UL87 family IBN_N PF03810.14 CDI74114.1 - 9.7e-11 41.4 0.0 2e-10 40.4 0.0 1.6 2 0 0 2 2 2 1 Importin-beta N-terminal domain TBCC PF07986.7 CDI74115.1 - 2.9e-15 55.7 0.6 2.9e-15 55.7 0.4 2.2 3 0 0 3 3 3 1 Tubulin binding cofactor C SseC PF04888.7 CDI74115.1 - 0.0034 16.7 14.3 0.0034 16.7 9.9 6.2 6 0 0 6 6 6 1 Secretion system effector C (SseC) like family Spt20 PF12090.3 CDI74115.1 - 0.0063 15.8 28.9 0.045 13.1 0.1 4.6 5 0 0 5 5 5 3 Spt20 family DUF1764 PF08576.5 CDI74115.1 - 0.33 11.7 0.1 0.33 11.7 0.1 5.0 4 1 0 4 4 4 0 Eukaryotic protein of unknown function (DUF1764) Herpes_UL87 PF03043.9 CDI74115.1 - 1.8 6.8 17.0 0.35 9.2 1.5 3.0 2 2 0 2 2 2 0 Herpesvirus UL87 family FimP PF09766.4 CDI74115.1 - 2.1 7.3 44.9 0.081 11.9 3.3 4.3 4 0 0 4 4 4 0 Fms-interacting protein zf-DHHC PF01529.15 CDI74115.1 - 5 6.4 13.6 6 6.2 0.0 3.6 4 0 0 4 4 4 0 DHHC palmitoyltransferase Neur_chan_memb PF02932.11 CDI74115.1 - 8.5 6.1 26.4 5.5 6.8 10.8 3.4 2 2 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Macoilin PF09726.4 CDI74117.1 - 0.067 11.4 25.1 0.076 11.2 17.4 1.1 1 0 0 1 1 1 0 Transmembrane protein PAT1 PF09770.4 CDI74117.1 - 0.084 11.1 27.9 0.1 10.7 19.3 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TFIIA PF03153.8 CDI74117.1 - 0.16 11.8 24.5 0.25 11.1 17.0 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Suf PF05843.9 CDI74117.1 - 3.1 7.4 15.9 4.5 6.9 11.0 1.4 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF4175 PF13779.1 CDI74117.1 - 5.2 4.6 30.0 7.2 4.1 20.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) DUF4407 PF14362.1 CDI74117.1 - 7.9 5.3 10.9 11 4.8 7.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) AUX_IAA PF02309.11 CDI74117.1 - 8.1 6.1 15.5 13 5.4 10.7 1.5 1 0 0 1 1 1 0 AUX/IAA family Pkinase PF00069.20 CDI74118.1 - 1.6e-31 109.4 7.6 5.1e-13 48.7 0.0 4.1 3 1 1 4 4 4 3 Protein kinase domain Pkinase_Tyr PF07714.12 CDI74118.1 - 2.4e-14 53.0 5.7 4.6e-06 25.8 3.8 2.5 2 1 0 2 2 2 2 Protein tyrosine kinase Plasmodium_Vir PF05795.6 CDI74118.1 - 0.29 10.2 11.6 0.9 8.6 3.2 2.4 2 0 0 2 2 2 0 Plasmodium vivax Vir protein DUF775 PF05603.7 CDI74119.1 - 0.031 13.7 15.4 0.035 13.6 10.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF775) FAM176 PF14851.1 CDI74119.1 - 1.3 8.6 7.1 1.5 8.4 4.9 1.1 1 0 0 1 1 1 0 FAM176 family TMEM237 PF15383.1 CDI74119.1 - 1.7 7.7 8.4 1.8 7.6 5.8 1.1 1 0 0 1 1 1 0 Transmembrane protein 237 DUF2052 PF09747.4 CDI74119.1 - 1.9 8.4 17.6 2 8.3 12.2 1.1 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) Folliculin PF11704.3 CDI74119.1 - 1.9 8.0 10.0 2.1 7.8 6.9 1.1 1 0 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport PEX11 PF05648.9 CDI74119.1 - 2.8 7.1 6.9 3 7.0 4.8 1.1 1 0 0 1 1 1 0 Peroxisomal biogenesis factor 11 (PEX11) PKI PF02827.11 CDI74119.1 - 3.8 7.6 5.9 6 7.0 4.1 1.4 1 0 0 1 1 1 0 cAMP-dependent protein kinase inhibitor Ctr PF04145.10 CDI74119.1 - 5.4 7.0 8.3 5.8 6.9 5.7 1.1 1 0 0 1 1 1 0 Ctr copper transporter family DUF2126 PF09899.4 CDI74119.1 - 6 4.7 10.2 6.2 4.7 7.1 1.0 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) zf-DHHC PF01529.15 CDI74119.1 - 6.9 6.0 9.3 7.5 5.9 6.5 1.1 1 0 0 1 1 1 0 DHHC palmitoyltransferase FAM150 PF15129.1 CDI74119.1 - 8.2 6.3 9.0 9.3 6.1 6.3 1.2 1 0 0 1 1 1 0 FAM150 family Tim54 PF11711.3 CDI74119.1 - 8.6 4.8 10.6 8.6 4.8 7.3 1.0 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Pex14_N PF04695.8 CDI74120.1 - 0.011 15.7 6.3 0.013 15.5 4.4 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Med15 PF09606.5 CDI74120.1 - 0.014 13.6 16.9 0.012 13.8 11.7 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal BAF1_ABF1 PF04684.8 CDI74120.1 - 0.038 12.8 11.6 0.036 12.9 8.0 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor DUF3408 PF11888.3 CDI74120.1 - 0.084 12.7 5.8 0.11 12.3 4.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) Peptidase_S49_N PF08496.5 CDI74120.1 - 0.13 12.0 4.8 0.16 11.7 3.3 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal AUX_IAA PF02309.11 CDI74120.1 - 0.14 11.9 3.2 0.14 11.8 2.2 1.1 1 0 0 1 1 1 0 AUX/IAA family FCP1_C PF09309.5 CDI74120.1 - 0.17 11.1 5.8 0.17 11.1 4.0 1.2 1 0 0 1 1 1 0 FCP1, C-terminal Spt20 PF12090.3 CDI74120.1 - 0.19 11.0 7.4 0.22 10.8 5.1 1.1 1 0 0 1 1 1 0 Spt20 family Suf PF05843.9 CDI74120.1 - 0.2 11.3 9.0 0.23 11.1 6.2 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) eIF-3_zeta PF05091.7 CDI74120.1 - 0.22 10.1 5.8 0.2 10.2 4.0 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Spore_coat_CotO PF14153.1 CDI74120.1 - 0.3 10.5 9.1 0.32 10.4 6.3 1.1 1 0 0 1 1 1 0 Spore coat protein CotO FimP PF09766.4 CDI74120.1 - 0.35 9.8 11.2 0.36 9.8 7.7 1.1 1 0 0 1 1 1 0 Fms-interacting protein DUF1764 PF08576.5 CDI74120.1 - 0.39 11.5 6.5 0.48 11.2 4.5 1.2 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) DUF3043 PF11241.3 CDI74120.1 - 0.45 10.0 3.5 0.56 9.7 2.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) Herpes_U34 PF04541.8 CDI74120.1 - 0.48 9.2 3.3 0.74 8.6 2.3 1.3 1 0 0 1 1 1 0 Herpesvirus virion protein U34 APC_CDC26 PF10471.4 CDI74120.1 - 0.49 11.1 14.7 1.1 10.1 10.2 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex APC subunit 1 PAT1 PF09770.4 CDI74120.1 - 0.54 8.4 17.1 0.55 8.4 11.9 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 RAB3GAP2_N PF14655.1 CDI74120.1 - 0.61 9.0 6.0 0.67 8.8 4.1 1.1 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus DUF4175 PF13779.1 CDI74120.1 - 0.64 7.6 19.7 0.68 7.5 13.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Activator_LAG-3 PF11498.3 CDI74120.1 - 0.8 8.3 23.3 1 8.0 16.2 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Pex16 PF08610.5 CDI74120.1 - 1.2 8.0 4.3 1.2 8.0 3.0 1.1 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) DUF4557 PF15101.1 CDI74120.1 - 1.4 8.6 11.2 1.7 8.4 7.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) Ndc1_Nup PF09531.5 CDI74120.1 - 1.6 7.0 5.5 1.7 6.9 3.8 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF3154 PF11351.3 CDI74120.1 - 1.7 8.4 8.1 2.6 7.8 5.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3154) PHD_3 PF13922.1 CDI74120.1 - 3.4 7.9 10.0 5.7 7.2 6.9 1.4 1 0 0 1 1 1 0 PHD domain of transcriptional enhancer, Asx DUF3597 PF12200.3 CDI74120.1 - 4.3 7.7 6.5 9.1 6.6 4.5 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF3597) DUF3729 PF12526.3 CDI74120.1 - 6.3 8.1 8.0 3.8 8.8 3.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3729) BRF1 PF07741.8 CDI74120.1 - 7.4 6.8 10.2 12 6.2 7.1 1.4 1 1 0 1 1 1 0 Brf1-like TBP-binding domain SHR3_chaperone PF08229.6 CDI74120.1 - 7.5 5.4 9.1 9.9 5.0 6.3 1.1 1 0 0 1 1 1 0 ER membrane protein SH3 Med15 PF09606.5 CDI74121.1 - 0.0019 16.5 16.3 0.0023 16.2 11.3 1.0 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal FhuF PF06276.7 CDI74121.1 - 0.037 13.9 1.9 0.05 13.5 1.3 1.1 1 0 0 1 1 1 0 Ferric iron reductase FhuF-like transporter UPF0118 PF01594.11 CDI74121.1 - 0.073 12.0 0.7 0.095 11.6 0.5 1.1 1 0 0 1 1 1 0 Domain of unknown function DUF20 Activator_LAG-3 PF11498.3 CDI74122.1 - 0.0029 16.4 45.0 0.0029 16.4 31.2 8.7 7 2 0 8 8 8 4 Transcriptional activator LAG-3 Auxin_canalis PF05703.6 CDI74125.1 - 0.012 15.4 22.0 0.015 15.0 15.2 1.2 1 0 0 1 1 1 0 Auxin canalisation Med15 PF09606.5 CDI74125.1 - 0.091 10.9 67.9 0.13 10.4 47.1 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF92 PF01940.11 CDI74125.1 - 2.4 7.2 5.3 4.1 6.4 3.7 1.3 1 0 0 1 1 1 0 Integral membrane protein DUF92 DUF4613 PF15390.1 CDI74125.1 - 2.4 6.2 24.4 3.7 5.6 16.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) PLRV_ORF5 PF01690.12 CDI74125.1 - 3.2 6.8 31.0 3.9 6.5 21.5 1.0 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein TFIIA PF03153.8 CDI74125.1 - 3.8 7.3 48.5 5.3 6.8 33.6 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit IncA PF04156.9 CDI74127.1 - 0.00076 19.1 19.3 0.00076 19.1 13.4 2.2 2 0 0 2 2 2 1 IncA protein CbiQ PF02361.11 CDI74127.1 - 0.0012 18.4 6.7 0.0026 17.3 4.6 1.6 1 0 0 1 1 1 1 Cobalt transport protein SR-25 PF10500.4 CDI74127.1 - 0.0073 15.7 4.2 0.015 14.7 2.9 1.4 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein RCC1_2 PF13540.1 CDI74127.1 - 0.031 13.8 15.8 0.11 12.1 0.1 5.4 5 1 1 6 6 6 0 Regulator of chromosome condensation (RCC1) repeat Spt20 PF12090.3 CDI74127.1 - 0.078 12.3 3.7 0.12 11.7 2.6 1.2 1 0 0 1 1 1 0 Spt20 family DUF3260 PF11658.3 CDI74127.1 - 0.079 11.0 6.4 0.14 10.2 4.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3260) YfhO PF09586.5 CDI74127.1 - 0.28 9.1 13.5 0.38 8.7 9.4 1.2 1 0 0 1 1 1 0 Bacterial membrane protein YfhO Spc7_N PF15402.1 CDI74127.1 - 0.57 8.1 7.3 0.87 7.5 5.1 1.2 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 Pex14_N PF04695.8 CDI74127.1 - 0.66 10.0 14.6 0.19 11.7 7.8 1.8 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Suf PF05843.9 CDI74127.1 - 1.4 8.5 7.3 2.2 7.9 5.0 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Activator_LAG-3 PF11498.3 CDI74127.1 - 1.6 7.3 21.1 2.4 6.7 14.6 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 BNIP3 PF06553.7 CDI74127.1 - 3.8 6.8 10.2 12 5.1 7.0 1.8 1 0 0 1 1 1 0 BNIP3 Shisa PF13908.1 CDI74127.1 - 4.1 7.5 23.1 1.1 9.3 0.1 3.0 2 1 0 2 2 2 0 Wnt and FGF inhibitory regulator Wzy_C PF04932.10 CDI74127.1 - 8.9 6.0 10.8 0.096 12.4 1.6 2.0 2 0 0 2 2 2 0 O-Antigen ligase DUF4460 PF14687.1 CDI74128.1 - 2.7e-10 40.0 14.8 2.4e-08 33.7 10.2 2.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4460) DUF2828 PF11443.3 CDI74128.1 - 0.00028 19.2 2.4 0.00031 19.0 1.6 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF2828) DRY_EERY PF09750.4 CDI74128.1 - 0.0018 18.3 5.6 0.077 13.1 0.3 2.2 2 0 0 2 2 2 2 Alternative splicing regulator Rpp20 PF12328.3 CDI74128.1 - 0.0028 17.3 6.8 0.19 11.3 0.1 2.2 2 0 0 2 2 2 2 Rpp20 subunit of nuclear RNase MRP and P 7tm_1 PF00001.16 CDI74128.1 - 0.0052 15.9 1.2 0.0073 15.4 0.8 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF2722 PF10846.3 CDI74128.1 - 0.023 13.7 12.9 0.028 13.4 1.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) DUF2229 PF09989.4 CDI74128.1 - 0.048 13.1 1.3 0.06 12.8 0.9 1.1 1 0 0 1 1 1 0 CoA enzyme activase uncharacterised domain (DUF2229) DDHD PF02862.12 CDI74128.1 - 0.067 12.9 4.7 0.092 12.5 3.2 1.2 1 0 0 1 1 1 0 DDHD domain PAT1 PF09770.4 CDI74128.1 - 0.22 9.7 31.4 0.24 9.5 21.7 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 APC_CDC26 PF10471.4 CDI74128.1 - 0.25 12.1 30.8 0.67 10.7 5.9 2.6 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit 1 Citrate_synt PF00285.16 CDI74128.1 - 0.31 9.7 2.8 0.34 9.5 2.0 1.1 1 0 0 1 1 1 0 Citrate synthase SOBP PF15279.1 CDI74128.1 - 0.44 10.8 11.4 0.53 10.6 7.9 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein DUF106 PF01956.11 CDI74128.1 - 0.45 10.0 6.4 0.69 9.4 4.4 1.3 1 0 0 1 1 1 0 Integral membrane protein DUF106 PHD_3 PF13922.1 CDI74128.1 - 0.46 10.7 16.3 0.61 10.3 2.6 2.3 2 0 0 2 2 2 0 PHD domain of transcriptional enhancer, Asx DUF2489 PF10675.4 CDI74128.1 - 1.9 8.1 23.9 2.9 7.5 4.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2489) Kinase-PPPase PF03618.9 CDI74128.1 - 1.9 7.8 9.4 1.5 8.2 0.9 2.1 1 1 1 2 2 2 0 Kinase/pyrophosphorylase U3_snoRNA_assoc PF08297.6 CDI74128.1 - 3.1 8.1 10.8 2.6 8.3 2.5 2.4 2 0 0 2 2 2 0 U3 snoRNA associated ERK-JNK_inhib PF15002.1 CDI74128.1 - 3.9 6.7 17.7 0.78 9.0 1.9 2.2 2 0 0 2 2 2 0 ERK and JNK pathways, inhibitor DUF1764 PF08576.5 CDI74128.1 - 5.3 7.8 11.6 6.8 7.5 1.9 2.3 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF1764) Dicty_REP PF05086.7 CDI74128.1 - 6.8 4.3 11.1 9.1 3.8 7.7 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Activator_LAG-3 PF11498.3 CDI74128.1 - 8.9 4.9 54.7 13 4.3 37.9 1.3 1 0 0 1 1 1 0 Transcriptional activator LAG-3 SR-25 PF10500.4 CDI74129.1 - 0.016 14.7 11.2 0.017 14.5 7.7 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Usp PF00582.21 CDI74129.1 - 0.067 13.3 1.4 0.09 12.9 1.0 1.3 1 0 0 1 1 1 0 Universal stress protein family TFIIA PF03153.8 CDI74129.1 - 0.38 10.6 24.1 0.4 10.5 16.7 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF3474 PF11960.3 CDI74129.1 - 0.44 10.5 4.7 0.49 10.4 3.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3474) Cwf_Cwc_15 PF04889.7 CDI74129.1 - 0.5 10.0 9.1 0.61 9.7 6.3 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein SprA-related PF12118.3 CDI74129.1 - 0.94 8.7 30.9 1.1 8.4 21.4 1.1 1 0 0 1 1 1 0 SprA-related family DUF1675 PF07897.6 CDI74129.1 - 1.3 8.7 12.4 1.4 8.7 8.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) FAD-oxidase_C PF02913.14 CDI74129.1 - 1.4 8.2 4.0 1.5 8.0 2.8 1.1 1 0 0 1 1 1 0 FAD linked oxidases, C-terminal domain Senescence_reg PF04520.8 CDI74129.1 - 1.4 9.3 8.3 2 8.8 5.8 1.2 1 0 0 1 1 1 0 Senescence regulator Rtf2 PF04641.7 CDI74129.1 - 1.7 7.7 11.3 2.1 7.4 7.8 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger F-protein PF00469.15 CDI74129.1 - 2.5 7.4 7.9 3 7.1 5.5 1.1 1 0 0 1 1 1 0 Negative factor, (F-Protein) or Nef TCP PF03634.8 CDI74129.1 - 2.9 8.2 15.9 4 7.8 11.0 1.3 1 0 0 1 1 1 0 TCP family transcription factor Peptidase_S8 PF00082.17 CDI74129.1 - 4.4 6.3 9.2 4.6 6.2 6.4 1.2 1 1 0 1 1 1 0 Subtilase family MRI PF15325.1 CDI74129.1 - 4.4 8.3 6.3 20 6.1 0.4 2.1 2 0 0 2 2 2 0 Modulator of retrovirus infection DUF572 PF04502.8 CDI74129.1 - 4.5 6.3 13.9 5.5 6.1 9.6 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF4228 PF14009.1 CDI74129.1 - 6.1 6.9 12.6 6.9 6.7 8.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4228) DDHD PF02862.12 CDI74129.1 - 6.7 6.4 10.3 8.6 6.0 7.2 1.2 1 0 0 1 1 1 0 DDHD domain DUF3881 PF12997.2 CDI74129.1 - 7.2 5.5 7.0 9.9 5.0 4.8 1.3 1 1 0 1 1 1 0 Domain of unknown function, E. rectale Gene description (DUF3881) DUF3752 PF12572.3 CDI74129.1 - 7.6 6.6 16.3 9.4 6.3 11.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3752) zf-RING_4 PF14570.1 CDI74130.1 - 1.1e-19 69.7 10.4 1.8e-19 69.0 7.2 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.1 CDI74130.1 - 5.6e-05 22.7 10.6 6.8e-05 22.4 6.3 1.9 1 1 1 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CDI74130.1 - 0.0011 18.7 12.1 0.0019 17.9 8.4 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 CDI74130.1 - 0.0045 16.6 10.5 0.0081 15.8 7.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-UDP PF14569.1 CDI74130.1 - 0.0058 16.3 3.5 0.014 15.1 2.4 1.6 1 0 0 1 1 1 1 Zinc-binding RING-finger zf-C3HC4_2 PF13923.1 CDI74130.1 - 0.08 12.9 11.0 0.094 12.7 7.0 1.6 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) RRN7 PF11781.3 CDI74130.1 - 0.082 12.4 3.2 0.091 12.2 0.5 2.1 2 0 0 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 RRM_1 PF00076.17 CDI74130.1 - 0.097 12.3 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Baculo_IE-1 PF05290.6 CDI74130.1 - 0.11 12.2 4.9 0.18 11.5 3.4 1.2 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) Rad50_zn_hook PF04423.9 CDI74130.1 - 0.43 10.0 5.0 5.2 6.6 0.7 2.4 2 0 0 2 2 2 0 Rad50 zinc hook motif DZR PF12773.2 CDI74130.1 - 1.3 8.8 9.9 1e+02 2.7 6.9 2.5 1 1 0 1 1 1 0 Double zinc ribbon zf-C3HC4_4 PF15227.1 CDI74130.1 - 1.5 8.7 13.3 1.9 8.4 7.8 2.1 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 CDI74130.1 - 4.2 7.1 10.9 4 7.2 6.6 1.7 1 1 0 1 1 1 0 zinc-RING finger domain Rtf2 PF04641.7 CDI74130.1 - 5.7 6.0 12.3 0.31 10.1 4.5 1.9 2 1 0 2 2 2 0 Rtf2 RING-finger PAT1 PF09770.4 CDI74131.1 - 0.41 8.8 16.9 0.44 8.7 11.7 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 RolB_RolC PF02027.12 CDI74131.1 - 0.46 9.6 3.2 0.5 9.5 2.2 1.1 1 0 0 1 1 1 0 RolB/RolC glucosidase family Spc7_N PF15402.1 CDI74131.1 - 0.97 7.3 4.7 1.2 7.0 3.2 1.0 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 DUF2870 PF11069.3 CDI74131.1 - 3.6 7.6 8.9 2.9 7.9 5.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2870) Med15 PF09606.5 CDI74131.1 - 4.4 5.3 28.1 4.2 5.4 19.5 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Activator_LAG-3 PF11498.3 CDI74131.1 - 6.2 5.4 33.5 7 5.2 23.2 1.3 1 0 0 1 1 1 0 Transcriptional activator LAG-3 EIF4E-T PF10477.4 CDI74131.1 - 6.6 5.4 8.5 6.9 5.3 5.9 1.1 1 0 0 1 1 1 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E Hydrolase_like2 PF13246.1 CDI74133.1 - 2.2e-09 37.1 12.2 7.9e-07 28.9 0.0 4.7 5 0 0 5 5 5 2 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 CDI74133.1 - 5.7e-08 33.1 0.2 0.0027 17.8 0.0 2.8 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase DUF2407_C PF13373.1 CDI74134.1 - 0.15 12.0 0.1 0.15 12.0 0.0 3.2 3 0 0 3 3 3 0 DUF2407 C-terminal domain RNA_pol_Rpb1_5 PF04998.12 CDI74134.1 - 0.41 9.8 4.3 0.14 11.4 0.1 1.9 2 0 0 2 2 2 0 RNA polymerase Rpb1, domain 5 Spt20 PF12090.3 CDI74134.1 - 1.6 8.0 29.5 0.36 10.1 1.3 3.3 3 0 0 3 3 3 0 Spt20 family UPF0233 PF06781.7 CDI74134.1 - 2.2 7.9 4.1 21 4.8 0.0 3.0 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0233) RAP1 PF07218.6 CDI74134.1 - 2.4 6.1 5.0 6.7 4.6 3.5 1.7 1 1 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) PBP1_TM PF14812.1 CDI74135.1 - 0.0012 19.1 5.5 0.0012 19.1 3.8 4.7 4 0 0 4 4 4 1 Transmembrane domain of transglycosylase PBP1 at N-terminal CD20 PF04103.10 CDI74135.1 - 0.0091 15.9 0.5 0.0091 15.9 0.3 6.9 6 1 0 6 6 6 2 CD20-like family Zip PF02535.17 CDI74135.1 - 5.7 5.8 34.3 0.012 14.6 4.7 4.1 4 0 0 4 4 4 0 ZIP Zinc transporter Ycf1 PF05758.7 CDI74135.1 - 8.1 4.0 49.3 0.88 7.2 10.2 3.5 3 0 0 3 3 3 0 Ycf1 Spore_YhcN_YlaJ PF09580.5 CDI74136.1 - 0.028 14.5 18.2 0.055 13.5 12.6 1.4 1 0 0 1 1 1 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) Ycf1 PF05758.7 CDI74137.1 - 0.32 8.6 10.4 0.018 12.8 2.3 1.9 2 0 0 2 2 2 0 Ycf1 Neur_chan_memb PF02932.11 CDI74137.1 - 3.6 7.3 7.7 0.62 9.9 0.8 2.5 2 1 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Herpes_UL87 PF03043.9 CDI74141.1 - 0.89 7.8 20.5 1 7.6 14.2 1.0 1 0 0 1 1 1 0 Herpesvirus UL87 family DUF1510 PF07423.6 CDI74141.1 - 2.2 7.5 32.8 3.2 7.0 22.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Hid1 PF12722.2 CDI74141.1 - 3.1 5.3 34.1 3.6 5.1 23.6 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF4045 PF13254.1 CDI74141.1 - 8.1 5.6 27.4 9.9 5.3 19.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Pkinase PF00069.20 CDI74143.1 - 6.2e-08 32.0 0.0 6.2e-08 32.0 0.0 3.4 2 1 0 3 3 3 1 Protein kinase domain Ribosomal_60s PF00428.14 CDI74143.1 - 0.0063 16.8 12.8 0.0063 16.8 8.9 9.5 4 3 3 7 7 7 1 60s Acidic ribosomal protein Dpy19 PF10034.4 CDI74143.1 - 0.072 11.2 0.1 0.11 10.6 0.1 1.2 1 0 0 1 1 1 0 Q-cell neuroblast polarisation IncA PF04156.9 CDI74143.1 - 0.23 11.0 31.6 0.16 11.5 10.7 3.7 3 1 0 3 3 3 0 IncA protein Claudin_2 PF13903.1 CDI74143.1 - 0.67 9.6 0.0 0.67 9.6 0.0 3.0 4 0 0 4 4 4 0 PMP-22/EMP/MP20/Claudin tight junction Nop14 PF04147.7 CDI74143.1 - 0.68 7.7 49.1 0.1 10.4 5.5 3.1 3 0 0 3 3 3 0 Nop14-like family Dynamin_N PF00350.18 CDI74143.1 - 4.3 7.1 13.9 4.9 6.9 1.1 3.2 3 0 0 3 3 3 0 Dynamin family LRR_4 PF12799.2 CDI74145.1 - 1.5e-05 24.4 17.8 0.0066 16.0 4.4 3.2 3 0 0 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CDI74145.1 - 0.0013 18.4 13.0 0.16 11.7 3.1 2.3 2 0 0 2 2 2 2 Leucine rich repeat LRR_6 PF13516.1 CDI74145.1 - 0.3 11.2 17.0 12 6.2 0.3 4.3 4 0 0 4 4 4 0 Leucine Rich repeat LRR_1 PF00560.28 CDI74145.1 - 1 9.6 21.4 1.9 8.8 1.0 4.2 4 0 0 4 4 4 0 Leucine Rich Repeat CbiD PF01888.12 CDI74146.1 - 0.028 13.4 8.2 0.062 12.2 5.7 1.5 1 0 0 1 1 1 0 CbiD OTU PF02338.14 CDI74147.1 - 2.7e-14 53.7 0.1 2.7e-14 53.7 0.0 3.4 4 0 0 4 4 4 1 OTU-like cysteine protease AAA_31 PF13614.1 CDI74147.1 - 0.085 12.7 1.2 0.17 11.8 0.8 1.5 1 0 0 1 1 1 0 AAA domain Vps53_N PF04100.7 CDI74149.1 - 1.4e-18 66.9 13.5 1.4e-18 66.9 9.4 4.8 3 2 1 4 4 4 1 Vps53-like, N-terminal DUF4207 PF13904.1 CDI74149.1 - 0.016 14.5 1.4 0.016 14.5 0.9 6.1 5 2 0 5 5 5 0 Domain of unknown function (DUF4207) SGT1 PF07093.6 CDI74149.1 - 6.4 5.0 65.0 0.12 10.7 15.9 3.0 2 1 0 2 2 2 0 SGT1 protein PAT1 PF09770.4 CDI74151.1 - 0.29 9.3 73.1 0.33 9.1 50.7 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Utp14 PF04615.8 CDI74151.1 - 0.31 9.1 38.8 0.37 8.9 26.9 1.0 1 0 0 1 1 1 0 Utp14 protein MIP-T3 PF10243.4 CDI74151.1 - 0.87 7.9 51.6 1.1 7.6 35.7 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 PLRV_ORF5 PF01690.12 CDI74151.1 - 1.2 8.1 31.1 1.4 7.9 21.6 1.0 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Mitofilin PF09731.4 CDI74151.1 - 4.1 5.9 32.2 5 5.6 22.4 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein DUF4045 PF13254.1 CDI74151.1 - 4.7 6.3 32.9 6 6.0 22.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Dapper PF15268.1 CDI74151.1 - 6.4 5.4 41.9 7.5 5.2 29.1 1.0 1 0 0 1 1 1 0 Dapper SAGA-Tad1 PF12767.2 CDI74151.1 - 8.6 5.9 35.0 12 5.4 24.2 1.3 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit Surface_antigen PF11054.3 CDI74153.1 - 1.7e-07 30.8 0.8 2.2e-07 30.5 0.5 1.2 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen DUF3053 PF11254.3 CDI74154.1 - 0.035 13.3 0.1 1.2 8.3 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3053) eIF-5a PF01287.15 CDI74154.1 - 0.049 13.5 0.5 0.57 10.1 0.1 2.6 3 0 0 3 3 3 0 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold DUF596 PF04591.7 CDI74154.1 - 0.056 13.3 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF596 CAP PF00188.21 CDI74155.1 - 0.0012 19.2 0.7 0.0023 18.4 0.3 1.6 1 1 1 2 2 2 1 Cysteine-rich secretory protein family CAP PF00188.21 CDI74156.1 - 3.6e-07 30.7 1.3 0.0099 16.3 0.1 2.5 2 1 0 2 2 2 2 Cysteine-rich secretory protein family Cofilin_ADF PF00241.15 CDI74157.1 - 5.6e-29 100.5 0.0 7.3e-29 100.2 0.0 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein DUF3093 PF11292.3 CDI74158.1 - 0.056 13.2 0.5 0.23 11.2 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3093) DUF4149 PF13664.1 CDI74158.1 - 0.8 9.8 6.1 2 8.5 3.3 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4149) DUF4282 PF14110.1 CDI74158.1 - 2.2 8.5 6.4 1.3 9.2 2.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4282) PrgI PF12666.2 CDI74158.1 - 8 6.6 7.0 8 6.6 0.4 2.3 2 0 0 2 2 2 0 PrgI family protein Rtf2 PF04641.7 CDI74159.1 - 3.5e-49 167.3 0.7 5.7e-49 166.6 0.5 1.3 1 0 0 1 1 1 1 Rtf2 RING-finger SR-25 PF10500.4 CDI74159.1 - 0.009 15.5 7.7 0.016 14.7 5.3 1.4 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein MKT1_C PF12246.3 CDI74159.1 - 0.14 11.1 0.3 4.6 6.1 0.0 2.2 2 0 0 2 2 2 0 Temperature dependent protein affecting M2 dsRNA replication Pex14_N PF04695.8 CDI74159.1 - 0.28 11.2 5.1 0.5 10.4 3.5 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region MRI PF15325.1 CDI74159.1 - 1.3 10.0 7.5 3.2 8.7 5.2 1.6 1 0 0 1 1 1 0 Modulator of retrovirus infection Aconitase PF00330.15 CDI74160.1 - 3.2e-142 474.2 0.0 4e-142 473.9 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 CDI74160.1 - 8e-41 139.2 0.0 1.3e-40 138.5 0.0 1.3 1 0 0 1 1 1 1 Aconitase C-terminal domain zf-RING_2 PF13639.1 CDI74161.1 - 3.8e-07 29.8 1.4 1.5e-06 27.9 0.4 2.1 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.1 CDI74161.1 - 0.0028 17.3 0.3 0.0058 16.3 0.2 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 CDI74161.1 - 0.0038 17.2 1.0 0.0068 16.4 0.2 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CDI74161.1 - 0.059 13.0 0.4 0.11 12.2 0.3 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 CDI74161.1 - 0.061 13.4 0.2 0.12 12.5 0.1 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger Med15 PF09606.5 CDI74162.1 - 0.00054 18.3 142.3 0.0006 18.1 98.7 1.1 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal Ribosomal_60s PF00428.14 CDI74162.1 - 0.94 9.9 17.0 1.3 9.4 0.2 2.4 2 0 0 2 2 2 0 60s Acidic ribosomal protein Utp14 PF04615.8 CDI74162.1 - 2.9 5.9 67.0 3.6 5.6 46.5 1.0 1 0 0 1 1 1 0 Utp14 protein Shadoo PF14999.1 CDI74162.1 - 6.2 6.6 8.3 85 3.0 5.2 2.1 2 0 0 2 2 2 0 Shadow of prion protein, neuroprotective AvrE PF11725.3 CDI74162.1 - 7.5 3.4 55.1 8.1 3.3 38.2 1.0 1 0 0 1 1 1 0 Pathogenicity factor BNR_3 PF13859.1 CDI74164.1 - 0.019 14.0 3.3 0.024 13.7 2.3 1.1 1 0 0 1 1 1 0 BNR repeat-like domain CD20 PF04103.10 CDI74164.1 - 0.029 14.2 5.2 0.51 10.2 0.8 2.1 2 0 0 2 2 2 0 CD20-like family DUF2217 PF10265.4 CDI74164.1 - 0.055 12.2 5.5 0.066 11.9 3.8 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) IncA PF04156.9 CDI74164.1 - 0.091 12.3 23.7 0.67 9.5 4.4 2.3 2 0 0 2 2 2 0 IncA protein DUF3735 PF12537.3 CDI74164.1 - 0.17 11.9 8.7 0.23 11.5 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3735) HemX PF04375.9 CDI74164.1 - 0.34 9.4 31.9 0.59 8.6 13.0 2.1 2 0 0 2 2 2 0 HemX DUF3115 PF11312.3 CDI74164.1 - 0.7 8.6 7.2 0.13 11.0 0.4 2.0 1 1 0 2 2 2 0 Protein of unknown function (DUF3115) Activator_LAG-3 PF11498.3 CDI74164.1 - 1.1 7.9 55.1 1.4 7.5 38.2 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Ribosomal_60s PF00428.14 CDI74164.1 - 2.2 8.7 11.5 4.3 7.8 8.0 1.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein FimP PF09766.4 CDI74164.1 - 4.8 6.1 25.0 0.85 8.6 5.0 2.1 2 0 0 2 2 2 0 Fms-interacting protein PAT1 PF09770.4 CDI74164.1 - 4.9 5.2 40.8 5.2 5.1 28.3 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Med15 PF09606.5 CDI74164.1 - 5 5.1 57.7 5.9 4.9 40.0 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal U1snRNP70_N PF12220.3 CDI74164.1 - 6 7.2 17.9 2.9 8.2 1.9 2.9 3 0 0 3 3 3 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal DOR PF14839.1 CDI74164.1 - 8.6 6.0 30.5 3 7.5 4.0 2.2 2 0 0 2 2 2 0 DOR family Oleosin PF01277.12 CDI74164.1 - 9.7 5.7 7.8 6.9 6.2 0.2 2.3 2 0 0 2 2 2 0 Oleosin SR-25 PF10500.4 CDI74165.1 - 2.4 7.5 40.8 1.3 8.3 13.4 2.1 1 1 1 2 2 2 0 Nuclear RNA-splicing-associated protein DTHCT PF08070.6 CDI74165.1 - 6.3 7.5 15.5 11 6.7 10.8 1.6 1 1 0 1 1 1 0 DTHCT (NUC029) region zf-XS PF03470.9 CDI74165.1 - 6.5 6.8 8.9 2.2 8.3 1.8 2.5 1 1 1 2 2 2 0 XS zinc finger domain CDK2AP PF09806.4 CDI74166.1 - 0.01 16.1 3.7 0.01 16.1 2.5 4.2 3 1 0 3 3 3 0 Cyclin-dependent kinase 2-associated protein SprA-related PF12118.3 CDI74166.1 - 0.48 9.7 79.5 1.1 8.5 26.4 2.4 2 0 0 2 2 2 0 SprA-related family Leu_Phe_trans PF03588.9 CDI74167.1 - 1e-05 24.7 0.1 5.8e-05 22.3 0.0 2.0 2 0 0 2 2 2 1 Leucyl/phenylalanyl-tRNA protein transferase Alk_phosphatase PF00245.15 CDI74167.1 - 0.12 11.0 1.5 0.18 10.4 1.0 1.2 1 0 0 1 1 1 0 Alkaline phosphatase Med15 PF09606.5 CDI74168.1 - 0.00016 20.0 37.3 0.00016 20.0 25.9 9.5 6 2 1 7 7 7 2 ARC105 or Med15 subunit of Mediator complex non-fungal MLANA PF14991.1 CDI74168.1 - 0.82 9.7 0.0 0.82 9.7 0.0 5.7 6 1 0 6 6 6 0 Protein melan-A O-antigen_lig PF13425.1 CDI74169.1 - 0.092 12.7 0.3 0.19 11.6 0.2 1.4 1 0 0 1 1 1 0 O-antigen ligase like membrane protein DUF2971 PF11185.3 CDI74169.1 - 5.2 7.8 15.0 1.2 9.9 1.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2971) 14-3-3 PF00244.15 CDI74170.1 - 0.00034 19.7 0.1 0.00034 19.7 0.0 3.1 4 0 0 4 4 4 1 14-3-3 protein TFIIA PF03153.8 CDI74170.1 - 0.15 11.9 37.4 0.61 9.9 18.5 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit BTV_NS2 PF04514.7 CDI74170.1 - 0.51 9.1 22.0 1.1 8.0 8.0 2.1 2 0 0 2 2 2 0 Bluetongue virus non-structural protein NS2 Utp14 PF04615.8 CDI74170.1 - 0.53 8.3 35.3 0.026 12.7 16.2 2.1 2 0 0 2 2 2 0 Utp14 protein Nop14 PF04147.7 CDI74170.1 - 1.1 7.0 26.0 0.021 12.7 10.5 2.2 2 0 0 2 2 2 0 Nop14-like family Med3 PF11593.3 CDI74170.1 - 4.8 6.3 57.0 0.54 9.4 31.2 2.1 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal SecY PF00344.15 CDI74171.1 - 7.9e-74 248.6 12.3 9.7e-74 248.3 8.5 1.0 1 0 0 1 1 1 1 SecY translocase ABC2_membrane_2 PF12679.2 CDI74171.1 - 0.17 10.6 5.0 0.26 10.1 1.1 2.1 2 0 0 2 2 2 0 ABC-2 family transporter protein Sporozoite_P67 PF05642.6 CDI74172.1 - 4.2e-05 21.6 0.0 4.2e-05 21.6 0.0 8.6 4 3 1 8 8 8 2 Sporozoite P67 surface antigen SPRY PF00622.23 CDI74172.1 - 0.00042 20.3 0.2 0.03 14.4 0.0 3.0 3 0 0 3 3 3 1 SPRY domain DUF3801 PF12687.2 CDI74172.1 - 0.21 11.1 0.0 0.042 13.4 4.5 7.3 7 1 0 7 7 7 0 Protein of unknown function (DUF3801) DUF4400 PF14348.1 CDI74173.1 - 0.05 12.9 5.3 0.061 12.7 3.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4400) Pex14_N PF04695.8 CDI74173.1 - 0.26 11.3 17.2 0.63 10.0 11.9 1.8 1 1 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF913 PF06025.7 CDI74173.1 - 0.48 9.1 2.4 0.59 8.8 1.7 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) CAF-1_p150 PF11600.3 CDI74173.1 - 0.99 8.7 9.5 1.3 8.4 6.6 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Stig1 PF04885.8 CDI74173.1 - 1.1 9.5 9.7 1.2 9.3 6.3 1.4 1 1 0 1 1 1 0 Stigma-specific protein, Stig1 DUF737 PF05300.6 CDI74173.1 - 2.1 8.2 12.3 3.8 7.4 8.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF737) DUF1360 PF07098.6 CDI74173.1 - 2.7 7.7 11.3 0.092 12.4 3.7 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1360) Suf PF05843.9 CDI74173.1 - 4.8 6.8 8.2 6.1 6.4 5.7 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Peptidase_S64 PF08192.6 CDI74173.1 - 6.9 4.8 7.3 6.5 4.9 5.0 1.1 1 0 0 1 1 1 0 Peptidase family S64 Spore_coat_CotO PF14153.1 CDI74174.1 - 0.043 13.2 22.5 0.28 10.6 4.1 2.8 2 0 0 2 2 2 0 Spore coat protein CotO DUF755 PF05501.6 CDI74175.1 - 0.0028 17.7 7.9 0.0028 17.7 5.5 17.1 14 3 3 17 17 17 2 Domain of unknown function (DUF755) Ribosomal_60s PF00428.14 CDI74175.1 - 0.012 16.0 1.4 0.012 16.0 1.0 20.7 16 6 1 17 17 17 0 60s Acidic ribosomal protein DUF687 PF05095.7 CDI74176.1 - 3.6 5.8 0.2 6.6 4.9 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF687) HHH_8 PF14716.1 CDI74177.1 - 0.02 15.0 0.0 0.34 11.1 0.0 2.5 2 0 0 2 2 2 0 Helix-hairpin-helix domain DUF4200 PF13863.1 CDI74180.1 - 0.0043 16.9 16.5 0.0043 16.9 11.5 5.0 3 1 1 5 5 5 2 Domain of unknown function (DUF4200) Baculo_PEP_C PF04513.7 CDI74180.1 - 5.7 6.7 12.7 9.3 6.0 1.7 3.2 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus FlaC_arch PF05377.6 CDI74180.1 - 9.8 6.1 9.2 32 4.5 0.5 4.2 4 0 0 4 4 4 0 Flagella accessory protein C (FlaC) Retrotrans_gag PF03732.12 CDI74181.1 - 0.091 12.8 0.2 1.1 9.4 0.0 2.3 2 0 0 2 2 2 0 Retrotransposon gag protein FPL PF09758.4 CDI74182.1 - 3e-44 150.3 4.1 5.6e-44 149.5 2.9 1.4 1 0 0 1 1 1 1 Uncharacterised conserved protein BTB PF00651.26 CDI74183.1 - 6.4e-07 29.3 0.0 1.6e-06 28.1 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain Mannosyl_trans PF05007.8 CDI74184.1 - 3.3e-47 161.3 27.5 1e-28 100.7 6.1 3.5 2 1 1 3 3 3 2 Mannosyltransferase (PIG-M) PIG-U PF06728.8 CDI74184.1 - 1.2e-15 57.2 0.4 1.2e-15 57.2 0.3 2.0 2 0 0 2 2 2 1 GPI transamidase subunit PIG-U APC_CDC26 PF10471.4 CDI74184.1 - 0.17 12.6 7.0 0.29 11.9 4.9 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex APC subunit 1 DUF2029 PF09594.5 CDI74184.1 - 5.9 6.3 35.0 1.2e+03 -1.3 20.2 3.9 2 1 0 2 2 2 0 Protein of unknown function (DUF2029) Myosin_head PF00063.16 CDI74185.1 - 1.5e-29 102.5 0.0 1.3e-21 76.3 0.0 3.9 2 2 0 2 2 2 2 Myosin head (motor domain) RCC1 PF00415.13 CDI74185.1 - 3.3e-29 100.8 2.0 6.8e-10 39.0 0.1 5.5 5 1 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 CDI74185.1 - 5.6e-10 38.5 26.0 2.1e-08 33.5 0.4 5.6 4 1 0 4 4 4 3 Regulator of chromosome condensation (RCC1) repeat IQ PF00612.22 CDI74185.1 - 2.3e-06 26.7 31.8 7e-05 22.1 1.0 6.0 6 0 0 6 6 6 3 IQ calmodulin-binding motif Kin17_mid PF10357.4 CDI74187.1 - 5.8e-43 145.5 2.7 5.8e-43 145.5 1.8 1.9 2 0 0 2 2 2 1 Domain of Kin17 curved DNA-binding protein zf-met PF12874.2 CDI74187.1 - 0.01 16.0 3.6 0.01 16.0 2.5 1.9 2 0 0 2 2 2 1 Zinc-finger of C2H2 type DUF3252 PF11623.3 CDI74187.1 - 0.025 13.9 0.0 0.046 13.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3252) zf-C2H2_jaz PF12171.3 CDI74187.1 - 0.21 11.7 8.1 0.084 13.0 3.2 2.1 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding DUF4525 PF15027.1 CDI74189.1 - 0.057 12.9 4.0 0.077 12.5 1.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4525) DHC_N2 PF08393.8 CDI74192.1 - 1.6e-85 287.0 0.3 1.6e-85 287.0 0.2 2.6 2 0 0 2 2 2 1 Dynein heavy chain, N-terminal region 2 Dynein_heavy PF03028.10 CDI74192.1 - 6.7e-81 272.3 1.0 1.8e-52 178.3 0.0 3.3 2 1 1 3 3 3 2 Dynein heavy chain and region D6 of dynein motor AAA_6 PF12774.2 CDI74192.1 - 7.6e-79 264.4 0.0 1.7e-78 263.3 0.0 1.5 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region D1 MT PF12777.2 CDI74192.1 - 1.7e-55 188.1 4.4 3.9e-55 186.9 3.0 1.6 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_9 PF12781.2 CDI74192.1 - 2.3e-26 92.0 0.1 4.3e-13 48.6 0.0 3.1 3 0 0 3 3 3 2 ATP-binding dynein motor region D5 AAA_8 PF12780.2 CDI74192.1 - 5.2e-16 58.4 0.0 2.3e-14 53.0 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 AAA_7 PF12775.2 CDI74192.1 - 1.5e-10 40.6 0.0 0.00018 20.7 0.0 2.9 3 0 0 3 3 3 2 P-loop containing dynein motor region D3 AAA_5 PF07728.9 CDI74192.1 - 1.4e-07 31.3 3.4 0.11 12.1 0.0 5.7 5 1 0 5 5 5 2 AAA domain (dynein-related subfamily) AAA PF00004.24 CDI74192.1 - 0.00029 21.0 0.8 0.23 11.6 0.0 4.2 4 0 0 4 4 4 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 CDI74192.1 - 0.0018 17.9 4.5 4 7.2 0.2 4.3 3 0 0 3 3 3 2 Part of AAA domain RNA_helicase PF00910.17 CDI74192.1 - 0.029 14.5 0.2 16 5.6 0.0 3.4 3 0 0 3 3 3 0 RNA helicase AAA_17 PF13207.1 CDI74192.1 - 0.092 13.5 0.2 1.3 9.8 0.0 3.0 3 0 0 3 3 2 0 AAA domain DUF1207 PF06727.6 CDI74194.1 - 0.018 13.8 0.9 0.022 13.6 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1207) OCIA PF07051.6 CDI74194.1 - 0.019 14.3 1.4 0.033 13.6 0.9 1.4 1 0 0 1 1 1 0 Ovarian carcinoma immunoreactive antigen (OCIA) DDHD PF02862.12 CDI74194.1 - 0.029 14.1 3.5 0.035 13.9 2.4 1.1 1 0 0 1 1 1 0 DDHD domain Folliculin PF11704.3 CDI74194.1 - 0.12 11.9 3.3 0.19 11.2 2.3 1.3 1 0 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport COX6A PF02046.10 CDI74194.1 - 0.13 12.2 9.0 0.54 10.1 0.2 2.1 1 1 0 2 2 2 0 Cytochrome c oxidase subunit VIa Spt20 PF12090.3 CDI74194.1 - 0.33 10.3 9.3 0.5 9.6 6.4 1.3 1 0 0 1 1 1 0 Spt20 family Fes1 PF08609.5 CDI74194.1 - 0.41 11.1 3.6 0.19 12.2 0.5 1.9 2 0 0 2 2 2 0 Nucleotide exchange factor Fes1 Pex16 PF08610.5 CDI74194.1 - 0.5 9.3 4.2 0.62 8.9 2.9 1.3 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) Peptidase_S49_N PF08496.5 CDI74194.1 - 1.9 8.3 7.2 0.61 9.8 3.0 1.5 2 0 0 2 2 2 0 Peptidase family S49 N-terminal TraH_2 PF06871.6 CDI74194.1 - 2.5 7.4 6.8 8.4 5.7 0.1 2.1 2 0 0 2 2 2 0 TraH_2 MCPVI PF02993.9 CDI74194.1 - 2.8 8.0 12.8 3.3 7.7 8.9 1.1 1 0 0 1 1 1 0 Minor capsid protein VI Ribosomal_60s PF00428.14 CDI74194.1 - 3.9 7.9 29.2 0.76 10.2 16.1 2.4 2 1 0 2 2 2 0 60s Acidic ribosomal protein RED_N PF07808.8 CDI74194.1 - 5.6 6.1 13.0 0.69 9.0 6.2 1.5 2 0 0 2 2 2 0 RED-like protein N-terminal region RAB3GAP2_N PF14655.1 CDI74194.1 - 6.4 5.6 9.3 9.7 5.0 6.4 1.2 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus FlaG PF03646.10 CDI74194.1 - 7 6.8 19.0 2.8 8.1 8.4 2.1 2 0 0 2 2 2 0 FlaG protein Serinc PF03348.10 CDI74194.1 - 7.3 5.1 6.1 11 4.5 4.2 1.3 1 0 0 1 1 1 0 Serine incorporator (Serinc) TRAUB PF08164.7 CDI74195.1 - 7.2e-12 45.2 0.0 7.2e-12 45.2 0.0 3.4 3 1 0 3 3 3 1 Apoptosis-antagonizing transcription factor, C-terminal AATF-Che1 PF13339.1 CDI74195.1 - 0.0044 17.1 11.1 0.0044 17.1 7.7 2.4 1 1 1 2 2 2 1 Apoptosis antagonizing transcription factor PLRV_ORF5 PF01690.12 CDI74195.1 - 0.17 10.9 10.6 0.23 10.5 7.3 1.3 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Med15 PF09606.5 CDI74195.1 - 0.21 9.7 39.2 0.28 9.3 27.2 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Ribosomal_60s PF00428.14 CDI74195.1 - 2.5 8.5 10.1 0.39 11.1 3.9 2.1 2 0 0 2 2 2 0 60s Acidic ribosomal protein LMBR1 PF04791.11 CDI74195.1 - 7 5.1 7.0 9.8 4.6 4.9 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Elongin_A PF06881.6 CDI74196.1 - 0.13 12.6 1.9 0.19 12.1 0.8 1.7 1 1 0 1 1 1 0 RNA polymerase II transcription factor SIII (Elongin) subunit A Herpeto_peptide PF14409.1 CDI74196.1 - 0.15 11.8 0.0 0.41 10.4 0.0 1.7 1 0 0 1 1 1 0 Ribosomally synthesized peptide in Herpetosiphon CHU_C PF13585.1 CDI74196.1 - 0.16 11.8 0.2 0.59 10.0 0.0 1.9 1 1 1 2 2 2 0 C-terminal domain of CHU protein family Med15 PF09606.5 CDI74199.1 - 0.014 13.6 26.6 0.016 13.4 18.4 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal RskA PF10099.4 CDI74199.1 - 0.016 14.9 1.0 0.022 14.4 0.7 1.2 1 0 0 1 1 1 0 Anti-sigma-K factor rskA Ribosomal_60s PF00428.14 CDI74199.1 - 0.024 15.0 12.5 0.14 12.5 3.9 2.2 2 0 0 2 2 2 0 60s Acidic ribosomal protein ISN1 PF06437.6 CDI74199.1 - 0.055 12.1 4.0 0.066 11.9 2.7 1.1 1 0 0 1 1 1 0 IMP-specific 5'-nucleotidase DUF3620 PF12281.3 CDI74199.1 - 0.057 13.1 3.1 0.073 12.7 2.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3620) AMP-binding PF00501.23 CDI74199.1 - 0.15 10.4 0.5 0.2 9.9 0.3 1.1 1 0 0 1 1 1 0 AMP-binding enzyme LMBR1 PF04791.11 CDI74199.1 - 0.19 10.2 3.1 0.2 10.1 2.2 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein Suf PF05843.9 CDI74199.1 - 0.27 10.9 14.8 0.31 10.7 10.3 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) PBP_sp32 PF07222.7 CDI74199.1 - 0.44 9.6 14.6 0.49 9.5 10.1 1.1 1 0 0 1 1 1 0 Proacrosin binding protein sp32 SprA-related PF12118.3 CDI74199.1 - 0.5 9.6 28.7 0.64 9.2 19.9 1.1 1 0 0 1 1 1 0 SprA-related family DDHD PF02862.12 CDI74199.1 - 1.4 8.6 12.6 1.6 8.4 8.7 1.1 1 0 0 1 1 1 0 DDHD domain FimP PF09766.4 CDI74199.1 - 1.4 7.9 19.0 1.7 7.6 13.1 1.2 1 0 0 1 1 1 0 Fms-interacting protein PAT1 PF09770.4 CDI74199.1 - 1.6 6.8 25.4 1.9 6.6 17.6 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF4557 PF15101.1 CDI74199.1 - 1.7 8.4 17.0 2 8.1 11.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) FLO_LFY PF01698.11 CDI74199.1 - 1.9 7.2 11.9 2.4 6.9 8.2 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein CobT PF06213.7 CDI74199.1 - 2 7.5 14.8 2.3 7.2 10.2 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT UPF0560 PF10577.4 CDI74199.1 - 3.2 5.8 14.9 3.2 5.9 10.3 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Band_3_cyto PF07565.8 CDI74199.1 - 3.3 7.1 10.7 3.9 6.9 7.4 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain F-protein PF00469.15 CDI74199.1 - 3.4 6.9 10.9 3.7 6.8 7.6 1.2 1 0 0 1 1 1 0 Negative factor, (F-Protein) or Nef APG6 PF04111.7 CDI74199.1 - 4 6.3 16.3 4.6 6.1 11.3 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF4175 PF13779.1 CDI74199.1 - 4.4 4.8 37.5 5.1 4.6 26.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Peptidase_S64 PF08192.6 CDI74199.1 - 4.7 5.4 12.0 5.4 5.2 8.3 1.0 1 0 0 1 1 1 0 Peptidase family S64 YqfQ PF14181.1 CDI74199.1 - 4.8 7.1 19.9 1.3 9.0 10.9 1.8 2 0 0 2 2 2 0 YqfQ-like protein Serinc PF03348.10 CDI74199.1 - 5 5.7 9.9 5.3 5.6 6.8 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) Paf1 PF03985.8 CDI74199.1 - 5.2 5.6 19.5 6.2 5.4 13.5 1.0 1 0 0 1 1 1 0 Paf1 Neur_chan_memb PF02932.11 CDI74199.1 - 6 6.6 6.9 6.9 6.4 4.8 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF2215 PF10225.4 CDI74199.1 - 7.3 5.9 7.4 11 5.4 5.1 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) DUF3464 PF11947.3 CDI74199.1 - 8.4 5.8 11.9 15 5.0 8.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) Gag_spuma PF03276.9 CDI74199.1 - 8.8 4.5 20.6 9.7 4.3 14.3 1.1 1 0 0 1 1 1 0 Spumavirus gag protein Activator_LAG-3 PF11498.3 CDI74200.1 - 0.0019 17.0 27.9 0.0019 17.0 19.4 4.2 2 1 0 2 2 2 1 Transcriptional activator LAG-3 Shadoo PF14999.1 CDI74200.1 - 0.0025 17.6 1.1 0.0036 17.1 0.8 1.3 1 0 0 1 1 1 1 Shadow of prion protein, neuroprotective SNF PF00209.13 CDI74201.1 - 0.63 8.4 0.1 1 7.7 0.0 1.2 1 0 0 1 1 1 0 Sodium:neurotransmitter symporter family CTDII PF01556.13 CDI74202.1 - 0.026 14.4 0.1 0.051 13.4 0.1 1.5 1 0 0 1 1 1 0 DnaJ C terminal domain PIG-P PF08510.7 CDI74203.1 - 0.013 15.1 0.0 0.021 14.4 0.0 1.5 1 0 0 1 1 1 0 PIG-P Mito_fiss_reg PF05308.6 CDI74203.1 - 0.016 14.6 2.7 0.016 14.6 1.9 2.1 2 0 0 2 2 2 0 Mitochondrial fission regulator TGF_beta PF00019.15 CDI74203.1 - 0.041 14.1 2.8 0.081 13.2 1.9 1.4 1 0 0 1 1 1 0 Transforming growth factor beta like domain Pex24p PF06398.6 CDI74203.1 - 0.053 12.3 1.7 0.075 11.8 1.2 1.3 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin Suf PF05843.9 CDI74203.1 - 0.084 12.5 6.3 0.13 11.9 4.4 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) UPF0182 PF03699.8 CDI74203.1 - 0.37 8.6 3.2 0.51 8.2 2.2 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0182) TMEM51 PF15345.1 CDI74203.1 - 1.3 8.6 5.5 2.9 7.5 3.8 1.4 1 0 0 1 1 1 0 Transmembrane protein 51 CAP_N PF01213.14 CDI74203.1 - 7.3 5.7 13.7 15 4.7 9.5 1.5 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal MDFI PF15316.1 CDI74203.1 - 9.9 6.1 8.2 55 3.6 4.5 2.1 1 1 1 2 2 2 0 MyoD family inhibitor Thioredoxin PF00085.15 CDI74204.1 - 3.6e-07 29.8 0.0 6e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_6 PF13848.1 CDI74204.1 - 0.0077 16.0 0.0 0.016 14.9 0.0 1.4 1 1 0 1 1 1 1 Thioredoxin-like domain PAT1 PF09770.4 CDI74206.1 - 7.1 4.7 112.7 2 6.5 38.4 2.2 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 14-3-3 PF00244.15 CDI74208.1 - 1.4e-108 361.4 9.6 1.8e-108 361.1 6.7 1.0 1 0 0 1 1 1 1 14-3-3 protein DUF4085 PF13315.1 CDI74208.1 - 0.46 9.8 4.8 0.1 11.9 0.7 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4085) EGF_CA PF07645.10 CDI74209.1 - 2.9e-26 91.1 70.4 8.4e-11 41.6 5.3 5.3 5 0 0 5 5 5 5 Calcium-binding EGF domain EGF_3 PF12947.2 CDI74209.1 - 1.2e-12 47.6 67.7 1.8e-06 27.8 6.6 6.0 5 1 1 6 6 6 5 EGF domain cEGF PF12662.2 CDI74209.1 - 2.8e-11 42.8 31.5 0.00011 21.7 0.2 6.4 6 0 0 6 6 6 4 Complement Clr-like EGF-like EGF PF00008.22 CDI74209.1 - 1.3e-05 25.0 64.9 0.00054 19.8 4.9 6.6 6 1 1 7 7 7 4 EGF-like domain EGF_MSP1_1 PF12946.2 CDI74209.1 - 0.0084 15.8 7.9 0.0084 15.8 5.4 4.6 4 0 0 4 4 4 2 MSP1 EGF domain 1 FXa_inhibition PF14670.1 CDI74209.1 - 0.018 15.1 8.4 0.018 15.1 5.8 6.1 6 0 0 6 6 6 0 Coagulation Factor Xa inhibitory site hEGF PF12661.2 CDI74209.1 - 0.18 11.9 14.4 1.4 9.1 0.3 5.2 3 0 0 3 3 3 0 Human growth factor-like EGF DIE2_ALG10 PF04922.7 CDI74210.1 - 1.7 7.6 1.2 4.6 6.1 0.8 1.7 1 0 0 1 1 1 0 DIE2/ALG10 family MIP-T3 PF10243.4 CDI74212.1 - 0.83 8.0 25.1 0.94 7.8 17.4 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 CT47 PF15623.1 CDI74213.1 - 0.0094 15.7 16.0 0.013 15.3 11.1 1.1 1 0 0 1 1 1 1 Cancer/testis gene family 47 Suf PF05843.9 CDI74213.1 - 0.017 14.8 2.5 0.018 14.7 1.7 1.0 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) R_equi_Vir PF05526.6 CDI74213.1 - 0.043 13.4 4.7 0.055 13.1 3.3 1.2 1 0 0 1 1 1 0 Rhodococcus equi virulence-associated protein DivIC PF04977.10 CDI74213.1 - 0.12 11.8 9.3 0.25 10.8 6.5 1.5 1 0 0 1 1 1 0 Septum formation initiator zf-DHHC PF01529.15 CDI74213.1 - 0.12 11.7 0.1 0.13 11.6 0.0 1.1 1 0 0 1 1 1 0 DHHC palmitoyltransferase DUF788 PF05620.6 CDI74213.1 - 0.42 10.4 2.7 0.65 9.8 1.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF788) DUF4366 PF14283.1 CDI74213.1 - 0.54 9.6 5.3 0.77 9.1 3.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) MSP1_C PF07462.6 CDI74213.1 - 1.6 6.9 5.4 1.7 6.9 3.8 1.1 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus DUF162 PF02589.10 CDI74213.1 - 2.6 7.5 5.9 2.9 7.3 4.1 1.1 1 0 0 1 1 1 0 Uncharacterised ACR, YkgG family COG1556 HlyD PF00529.15 CDI74213.1 - 3.4 6.9 26.0 3.7 6.7 18.0 1.0 1 0 0 1 1 1 0 HlyD family secretion protein Peptidase_S15 PF02129.13 CDI74213.1 - 8.5 5.7 7.1 11 5.3 4.9 1.1 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) O-antigen_lig PF13425.1 CDI74217.1 - 7.8 6.4 7.8 15 5.5 1.9 3.6 4 1 0 4 4 4 0 O-antigen ligase like membrane protein Ribosomal_60s PF00428.14 CDI74219.1 - 0.045 14.1 10.7 0.045 14.1 7.4 2.1 2 0 0 2 2 2 0 60s Acidic ribosomal protein DUF732 PF05305.9 CDI74219.1 - 0.28 11.2 15.2 0.16 12.0 8.9 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF732) RseC_MucC PF04246.7 CDI74219.1 - 1.4 8.4 9.3 0.12 11.9 1.5 2.4 1 1 1 2 2 2 0 Positive regulator of sigma(E), RseC/MucC Med15 PF09606.5 CDI74220.1 - 0.4 8.8 76.1 0.06 11.5 32.7 2.1 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal SPT16 PF08644.6 CDI74220.1 - 1.5 8.6 7.1 0.21 11.3 1.2 2.1 2 0 0 2 2 2 0 FACT complex subunit (SPT16/CDC68) Pro_isomerase PF00160.16 CDI74221.1 - 4.5e-12 46.4 0.1 2.6e-06 27.7 0.0 2.0 1 1 1 2 2 2 2 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Bromodomain PF00439.20 CDI74223.1 - 2.1e-16 59.5 0.1 3.3e-16 58.9 0.1 1.3 1 0 0 1 1 1 1 Bromodomain 3HBOH PF10605.4 CDI74223.1 - 0.0049 15.0 1.6 0.0071 14.4 1.1 1.1 1 0 0 1 1 1 1 3HB-oligomer hydrolase (3HBOH) DUF1697 PF08002.6 CDI74223.1 - 0.048 13.6 0.8 0.1 12.6 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1697) DUF1510 PF07423.6 CDI74226.1 - 0.00015 21.1 9.5 0.00015 21.1 6.6 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1510) SR-25 PF10500.4 CDI74226.1 - 0.0016 17.9 58.2 0.64 9.4 17.5 2.3 1 1 1 2 2 2 2 Nuclear RNA-splicing-associated protein EphA2_TM PF14575.1 CDI74226.1 - 0.0054 17.0 0.1 0.0054 17.0 0.1 4.4 3 1 0 3 3 3 1 Ephrin type-A receptor 2 transmembrane domain Baculo_11_kDa PF06143.6 CDI74226.1 - 0.016 14.5 0.3 0.016 14.5 0.2 4.4 4 2 0 4 4 4 0 Baculovirus 11 kDa family Conotoxin PF02950.12 CDI74226.1 - 0.021 15.5 2.9 0.021 15.5 2.0 4.2 2 2 2 4 4 4 0 Conotoxin NicO PF03824.11 CDI74226.1 - 0.052 12.8 0.2 0.052 12.8 0.1 1.9 2 0 0 2 2 2 0 High-affinity nickel-transport protein Cytochrom_B_N PF00033.14 CDI74226.1 - 0.056 12.7 0.0 0.056 12.7 0.0 2.3 3 0 0 3 3 3 0 Cytochrome b(N-terminal)/b6/petB L_HGMIC_fpl PF10242.4 CDI74226.1 - 0.1 12.6 0.2 0.23 11.4 0.2 1.6 1 0 0 1 1 1 0 Lipoma HMGIC fusion partner-like protein 7TM_GPCR_Srv PF10323.4 CDI74226.1 - 0.18 10.8 0.1 0.18 10.8 0.1 3.6 4 0 0 4 4 4 0 Serpentine type 7TM GPCR chemoreceptor Srv DUF4604 PF15377.1 CDI74226.1 - 4.2 7.5 37.0 0.023 14.9 4.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4604) UPF0564 PF10595.4 CDI74227.1 - 9.4e-06 24.7 12.5 9.4e-06 24.7 8.7 5.3 5 0 0 5 5 5 1 Uncharacterised protein family UPF0564 FAM60A PF15396.1 CDI74227.1 - 0.00084 19.1 4.0 0.00084 19.1 2.8 5.7 6 0 0 6 6 6 3 Protein Family FAM60A AAA_23 PF13476.1 CDI74227.1 - 0.0066 16.7 4.2 0.0066 16.7 2.9 5.0 5 0 0 5 5 5 3 AAA domain Plasmodium_Vir PF05795.6 CDI74228.1 - 0.015 14.5 0.0 0.015 14.5 0.0 4.9 3 3 0 4 4 4 0 Plasmodium vivax Vir protein Helicase_C PF00271.26 CDI74229.1 - 1.9e-09 37.2 0.0 1.9e-09 37.2 0.0 3.4 3 0 0 3 3 3 1 Helicase conserved C-terminal domain HA2 PF04408.18 CDI74229.1 - 3.2e-09 36.7 0.0 3.2e-09 36.7 0.0 5.1 4 1 0 4 4 4 1 Helicase associated domain (HA2) Ribosomal_60s PF00428.14 CDI74229.1 - 0.0058 17.0 5.9 0.0058 17.0 4.1 7.6 7 3 0 7 7 7 1 60s Acidic ribosomal protein Med15 PF09606.5 CDI74230.1 - 0.00022 19.5 57.5 0.0003 19.1 39.9 1.1 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal PAT1 PF09770.4 CDI74230.1 - 0.11 10.6 49.0 0.13 10.4 33.9 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SID-1_RNA_chan PF13965.1 CDI74230.1 - 1 7.4 12.2 1.4 7.0 8.5 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Macoilin PF09726.4 CDI74230.1 - 8 4.6 33.2 11 4.1 23.0 1.2 1 0 0 1 1 1 0 Transmembrane protein GAGA_bind PF06217.7 CDI74230.1 - 8.9 6.1 27.2 14 5.5 18.9 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family AAA_23 PF13476.1 CDI74231.1 - 0.00054 20.3 7.7 0.00054 20.3 5.4 5.4 5 1 0 5 5 5 1 AAA domain RabGAP-TBC PF00566.13 CDI74232.1 - 2.3e-08 33.7 0.3 3.7e-08 33.1 0.1 1.4 1 1 0 1 1 1 1 Rab-GTPase-TBC domain Macoilin PF09726.4 CDI74232.1 - 0.083 11.1 40.2 0.0045 15.3 21.6 2.1 2 0 0 2 2 2 0 Transmembrane protein DUF572 PF04502.8 CDI74232.1 - 0.1 11.8 20.4 0.23 10.6 14.1 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF4551 PF15087.1 CDI74232.1 - 2.7 6.2 20.3 4.5 5.5 14.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) MIP-T3 PF10243.4 CDI74232.1 - 4.7 5.5 15.4 9.3 4.5 10.7 1.5 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DDHD PF02862.12 CDI74232.1 - 7.7 6.2 23.5 1.5 8.5 12.6 2.3 2 0 0 2 2 2 0 DDHD domain Cwf_Cwc_15 PF04889.7 CDI74232.1 - 7.8 6.1 14.9 15 5.1 10.4 1.5 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein eIF-3_zeta PF05091.7 CDI74233.1 - 0.0078 14.8 7.1 0.016 13.8 4.9 1.4 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF1510 PF07423.6 CDI74233.1 - 1.4 8.1 14.3 3.2 7.0 1.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) Spore_coat_CotO PF14153.1 CDI74235.1 - 2.4e-07 30.3 11.0 2.7e-07 30.2 7.6 1.2 1 0 0 1 1 1 1 Spore coat protein CotO SAPS PF04499.10 CDI74235.1 - 2.5e-05 23.1 4.8 2.9e-05 22.9 3.3 1.1 1 0 0 1 1 1 1 SIT4 phosphatase-associated protein SPX PF03105.14 CDI74235.1 - 0.00034 20.4 8.7 0.00039 20.2 6.0 1.2 1 0 0 1 1 1 1 SPX domain SAGA-Tad1 PF12767.2 CDI74235.1 - 0.00044 19.9 14.7 0.00068 19.3 10.2 1.3 1 0 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit Ycf1 PF05758.7 CDI74235.1 - 0.00078 17.2 16.5 0.001 16.9 11.4 1.0 1 0 0 1 1 1 1 Ycf1 GPCR_chapero_1 PF11904.3 CDI74235.1 - 0.002 17.3 13.6 0.0028 16.8 9.4 1.2 1 0 0 1 1 1 1 GPCR-chaperone CDC45 PF02724.9 CDI74235.1 - 0.0024 15.9 15.1 0.0031 15.6 10.5 1.1 1 0 0 1 1 1 1 CDC45-like protein DUF2413 PF10310.4 CDI74235.1 - 0.014 14.2 21.1 0.019 13.8 14.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) LMBR1 PF04791.11 CDI74235.1 - 0.027 13.0 1.4 0.029 12.9 1.0 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Tim54 PF11711.3 CDI74235.1 - 0.035 12.7 10.6 0.069 11.7 7.4 1.4 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Mem_trans PF03547.13 CDI74235.1 - 0.039 12.2 2.2 0.042 12.1 1.5 1.1 1 0 0 1 1 1 0 Membrane transport protein DDHD PF02862.12 CDI74235.1 - 0.061 13.1 14.3 0.093 12.5 9.9 1.3 1 0 0 1 1 1 0 DDHD domain Otopetrin PF03189.8 CDI74235.1 - 0.096 11.6 0.9 0.11 11.4 0.6 1.2 1 0 0 1 1 1 0 Otopetrin Pox_Ag35 PF03286.9 CDI74235.1 - 0.096 12.1 15.6 0.16 11.4 10.8 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DUF4045 PF13254.1 CDI74235.1 - 0.098 11.9 17.1 0.13 11.4 11.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) TFIIA PF03153.8 CDI74235.1 - 0.12 12.2 33.8 0.18 11.7 23.4 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Paf1 PF03985.8 CDI74235.1 - 0.14 10.8 26.7 0.21 10.2 18.5 1.1 1 0 0 1 1 1 0 Paf1 Neur_chan_memb PF02932.11 CDI74235.1 - 0.23 11.3 15.5 0.43 10.4 10.7 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region FAM60A PF15396.1 CDI74235.1 - 0.24 11.1 18.8 0.34 10.6 13.0 1.2 1 0 0 1 1 1 0 Protein Family FAM60A DUF1510 PF07423.6 CDI74235.1 - 0.33 10.3 26.2 0.47 9.7 18.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) RR_TM4-6 PF06459.7 CDI74235.1 - 0.36 10.6 20.9 0.54 10.0 14.5 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Med15 PF09606.5 CDI74235.1 - 0.61 8.2 62.2 0.79 7.8 43.1 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal GAGA_bind PF06217.7 CDI74235.1 - 1 9.2 20.7 1.6 8.6 14.3 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family Raftlin PF15250.1 CDI74235.1 - 1.3 7.4 19.9 1.8 7.0 13.8 1.1 1 0 0 1 1 1 0 Raftlin CPSF100_C PF13299.1 CDI74235.1 - 1.3 9.1 16.4 3.2 7.9 11.3 1.6 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Paramyxo_ncap PF00973.14 CDI74235.1 - 2.1 6.9 17.2 2.8 6.5 11.9 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Hid1 PF12722.2 CDI74235.1 - 2.5 5.6 24.9 3.4 5.2 17.3 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein eIF-3_zeta PF05091.7 CDI74235.1 - 3 6.3 26.9 4.1 5.9 18.6 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) PIH1 PF08190.7 CDI74235.1 - 3.1 7.1 26.7 4.6 6.5 18.5 1.1 1 0 0 1 1 1 0 pre-RNA processing PIH1/Nop17 DUF342 PF03961.8 CDI74235.1 - 3.6 5.8 14.9 5.2 5.3 10.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Plasmodium_Vir PF05795.6 CDI74235.1 - 3.9 6.5 7.6 5.6 6.0 5.3 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein AUX_IAA PF02309.11 CDI74235.1 - 3.9 7.1 18.8 6.7 6.3 13.0 1.3 1 0 0 1 1 1 0 AUX/IAA family SprA-related PF12118.3 CDI74235.1 - 4.1 6.6 49.0 6.2 6.0 34.0 1.2 1 0 0 1 1 1 0 SprA-related family Herpes_UL87 PF03043.9 CDI74235.1 - 4.5 5.5 12.4 6.1 5.0 8.6 1.1 1 0 0 1 1 1 0 Herpesvirus UL87 family DUF1675 PF07897.6 CDI74235.1 - 4.5 7.0 15.4 6.7 6.4 10.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) Herpes_DNAp_acc PF04929.7 CDI74235.1 - 5 5.9 21.9 6.8 5.5 15.2 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor AvrE PF11725.3 CDI74235.1 - 6.4 3.6 22.3 8.1 3.3 15.5 1.0 1 0 0 1 1 1 0 Pathogenicity factor Sec62 PF03839.11 CDI74235.1 - 7.3 5.9 19.0 11 5.2 13.2 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 Zip PF02535.17 CDI74235.1 - 7.8 5.4 12.8 12 4.8 8.9 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Band_3_cyto PF07565.8 CDI74235.1 - 8.1 5.8 20.7 16 4.9 14.3 1.5 1 0 0 1 1 1 0 Band 3 cytoplasmic domain DUF853 PF05872.7 CDI74235.1 - 9.9 4.3 14.4 15 3.8 10.0 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) Na_trans_assoc PF06512.8 CDI74236.1 - 0.00093 19.2 6.3 0.0013 18.8 4.3 1.2 1 0 0 1 1 1 1 Sodium ion transport-associated Mucin PF01456.12 CDI74236.1 - 0.00098 18.9 3.7 0.00098 18.9 2.6 2.2 1 1 0 2 2 2 1 Mucin-like glycoprotein EphA2_TM PF14575.1 CDI74236.1 - 0.14 12.5 0.2 0.14 12.5 0.1 2.6 2 1 0 2 2 1 0 Ephrin type-A receptor 2 transmembrane domain DUF45 PF01863.12 CDI74236.1 - 0.17 11.6 5.9 0.067 12.9 0.6 2.1 2 0 0 2 2 2 0 Protein of unknown function DUF45 CD20 PF04103.10 CDI74236.1 - 0.54 10.1 9.7 0.95 9.3 0.3 2.5 3 0 0 3 3 3 0 CD20-like family DUF2232 PF09991.4 CDI74236.1 - 0.59 9.0 12.0 0.58 9.1 2.8 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2232) GRP PF07172.6 CDI74236.1 - 0.64 10.5 0.1 0.64 10.5 0.1 2.5 1 1 0 2 2 2 0 Glycine rich protein family DUF1635 PF07795.6 CDI74236.1 - 0.87 8.9 23.4 0.019 14.3 8.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1635) 7tm_1 PF00001.16 CDI74236.1 - 1.1 8.3 3.5 1.3 8.1 0.1 2.1 2 1 1 3 3 3 0 7 transmembrane receptor (rhodopsin family) Tau95 PF09734.4 CDI74236.1 - 1.5 8.0 8.0 2.2 7.4 5.6 1.2 1 0 0 1 1 1 0 RNA polymerase III transcription factor (TF)IIIC subunit Med15 PF09606.5 CDI74236.1 - 1.6 6.8 57.6 2.6 6.1 39.9 1.4 1 1 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Serinc PF03348.10 CDI74236.1 - 2.2 6.8 13.8 1.7 7.3 0.4 2.2 2 0 0 2 2 2 0 Serine incorporator (Serinc) DUF2215 PF10225.4 CDI74236.1 - 2.6 7.4 8.5 0.44 9.9 2.0 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2215) DUF3449 PF11931.3 CDI74236.1 - 3.2 7.1 11.7 5.8 6.3 3.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3449) Mem_trans PF03547.13 CDI74236.1 - 3.4 5.8 8.5 1.5 7.0 2.7 2.0 2 0 0 2 2 2 0 Membrane transport protein DUF4131 PF13567.1 CDI74236.1 - 5.8 6.2 14.9 0.033 13.5 1.2 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF4131) 60KD_IMP PF02096.15 CDI74236.1 - 6.5 6.3 18.0 2.9 7.5 0.9 2.2 2 0 0 2 2 2 0 60Kd inner membrane protein DUF2149 PF09919.4 CDI74236.1 - 9.2 6.4 9.3 9.7 6.3 2.3 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2149) SprA-related PF12118.3 CDI74237.1 - 0.00015 21.1 46.3 0.00015 21.1 32.1 7.3 5 2 2 7 7 7 2 SprA-related family CAF-1_p150 PF11600.3 CDI74237.1 - 0.00028 20.3 29.9 0.00028 20.3 20.7 9.6 5 2 3 8 8 8 2 Chromatin assembly factor 1 complex p150 subunit, N-terminal Ku_PK_bind PF08785.6 CDI74238.1 - 7.8e-09 35.4 17.1 9.8e-07 28.6 1.8 4.3 3 2 1 4 4 4 2 Ku C terminal domain like Uteroglobin PF01099.12 CDI74238.1 - 0.085 12.6 0.6 18 5.2 0.0 2.7 2 0 0 2 2 2 0 Uteroglobin family Shadoo PF14999.1 CDI74238.1 - 0.2 11.5 17.8 0.27 11.0 0.4 2.3 2 0 0 2 2 2 0 Shadow of prion protein, neuroprotective FAM60A PF15396.1 CDI74238.1 - 0.56 9.9 11.8 2.2 8.0 3.5 2.1 2 0 0 2 2 2 0 Protein Family FAM60A Ribosomal_60s PF00428.14 CDI74238.1 - 2.2 8.7 46.7 1.7 9.0 10.1 3.3 2 2 1 3 3 3 0 60s Acidic ribosomal protein DUF2407_C PF13373.1 CDI74238.1 - 2.3 8.1 15.0 6.1 6.7 1.3 2.4 2 0 0 2 2 2 0 DUF2407 C-terminal domain BTV_NS2 PF04514.7 CDI74238.1 - 2.7 6.8 20.7 0.98 8.2 7.3 2.1 2 0 0 2 2 2 0 Bluetongue virus non-structural protein NS2 eIF-3_zeta PF05091.7 CDI74238.1 - 3.2 6.2 22.5 0.75 8.3 7.7 2.3 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) OMP_b-brl PF13505.1 CDI74238.1 - 4.5 7.1 11.9 3.2 7.6 1.7 2.4 2 0 0 2 2 2 0 Outer membrane protein beta-barrel domain Corona_nucleoca PF00937.13 CDI74238.1 - 5.3 5.8 20.1 3.3 6.5 6.0 2.2 2 0 0 2 2 2 0 Coronavirus nucleocapsid protein CPSF100_C PF13299.1 CDI74238.1 - 8.4 6.5 17.4 7.8 6.6 5.6 2.4 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal Exonuc_VII_L PF02601.10 CDI74240.1 - 0.58 9.2 36.7 0.66 9.1 25.5 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit FimP PF09766.4 CDI74241.1 - 0.00028 20.0 8.0 0.00028 20.0 5.6 8.5 7 3 1 8 8 8 1 Fms-interacting protein N6_N4_Mtase PF01555.13 CDI74241.1 - 3.7 6.9 9.4 49 3.3 0.0 3.9 3 2 0 3 3 3 0 DNA methylase MSP1_C PF07462.6 CDI74242.1 - 0.66 8.2 10.3 0.0086 14.5 1.9 1.6 2 0 0 2 2 2 0 Merozoite surface protein 1 (MSP1) C-terminus DUF3597 PF12200.3 CDI74242.1 - 8.5 6.7 7.7 4.7 7.6 1.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3597) Spore_coat_CotO PF14153.1 CDI74243.1 - 0.16 11.4 14.0 0.21 10.9 9.7 1.2 1 0 0 1 1 1 0 Spore coat protein CotO Ycf1 PF05758.7 CDI74243.1 - 0.28 8.8 3.2 0.25 9.0 2.2 1.1 1 0 0 1 1 1 0 Ycf1 Pox_Ag35 PF03286.9 CDI74243.1 - 1 8.8 13.7 1.7 8.1 9.5 1.5 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Daxx PF03344.10 CDI74243.1 - 1.9 6.8 19.1 2.4 6.5 13.2 1.1 1 0 0 1 1 1 0 Daxx Family DUF2868 PF11067.3 CDI74243.1 - 5.9 5.9 6.4 7.6 5.5 4.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2868) Neur_chan_memb PF02932.11 CDI74243.1 - 6.8 6.4 6.0 9.1 6.0 4.2 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Spt20 PF12090.3 CDI74245.1 - 0.0007 18.9 0.9 0.00075 18.8 0.6 1.0 1 0 0 1 1 1 1 Spt20 family HemX PF04375.9 CDI74245.1 - 0.015 13.9 10.1 0.018 13.6 7.0 1.1 1 0 0 1 1 1 0 HemX BAF1_ABF1 PF04684.8 CDI74245.1 - 0.017 13.9 9.9 0.022 13.6 6.8 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Mitofilin PF09731.4 CDI74245.1 - 0.018 13.7 7.4 0.021 13.5 5.1 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Med15 PF09606.5 CDI74245.1 - 0.043 12.0 9.8 0.045 11.9 6.8 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal COG4 PF08318.7 CDI74245.1 - 0.14 10.9 1.6 0.16 10.6 1.1 1.1 1 0 0 1 1 1 0 COG4 transport protein RAB3GAP2_N PF14655.1 CDI74245.1 - 0.17 10.8 1.4 0.17 10.8 1.0 1.1 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus TMEM51 PF15345.1 CDI74245.1 - 0.25 11.0 3.9 0.31 10.7 2.7 1.2 1 0 0 1 1 1 0 Transmembrane protein 51 CDK2AP PF09806.4 CDI74245.1 - 0.31 11.2 8.6 0.36 11.0 5.9 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein PCYCGC PF13798.1 CDI74245.1 - 0.76 9.4 4.0 0.8 9.3 2.8 1.2 1 1 0 1 1 1 0 Protein of unknown function with PCYCGC motif Macoilin PF09726.4 CDI74245.1 - 0.84 7.8 9.9 1 7.5 6.9 1.0 1 0 0 1 1 1 0 Transmembrane protein DUF4175 PF13779.1 CDI74245.1 - 2.4 5.7 15.5 2.7 5.5 10.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) PPP4R2 PF09184.6 CDI74245.1 - 2.7 7.4 7.4 3.1 7.2 5.1 1.0 1 0 0 1 1 1 0 PPP4R2 DUF4407 PF14362.1 CDI74245.1 - 2.9 6.7 10.4 3.5 6.5 7.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Herpes_UL25 PF01499.11 CDI74245.1 - 3.9 5.6 6.5 5.2 5.2 4.5 1.2 1 0 0 1 1 1 0 Herpesvirus UL25 family Spore_coat_CotO PF14153.1 CDI74245.1 - 4.4 6.7 9.7 5.6 6.3 6.7 1.1 1 0 0 1 1 1 0 Spore coat protein CotO Ribosomal_60s PF00428.14 CDI74245.1 - 4.9 7.6 23.2 0.27 11.6 11.7 1.8 1 1 1 2 2 2 0 60s Acidic ribosomal protein E_Pc_C PF06752.7 CDI74245.1 - 5.9 6.3 13.8 7.3 6.0 9.6 1.1 1 0 0 1 1 1 0 Enhancer of Polycomb C-terminus DUF3138 PF11336.3 CDI74245.1 - 6.8 4.7 11.8 7.3 4.6 8.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) DUF4557 PF15101.1 CDI74245.1 - 7.3 6.3 7.9 8.4 6.1 5.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) rve PF00665.21 CDI74246.1 - 6.6e-13 48.8 0.0 9.4e-13 48.3 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.1 CDI74246.1 - 0.097 12.2 0.1 0.19 11.2 0.1 1.6 1 0 0 1 1 1 0 Integrase core domain gag-asp_proteas PF13975.1 CDI74247.1 - 6.5e-08 32.2 0.0 1.3e-07 31.3 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 CDI74247.1 - 9.8e-07 29.1 0.0 1.8e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.15 CDI74247.1 - 0.0037 17.1 0.0 0.0076 16.1 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease RVP_2 PF08284.6 CDI74247.1 - 0.12 12.3 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease DUF1758 PF05585.7 CDI74247.1 - 0.16 11.4 0.0 0.27 10.7 0.0 1.2 1 0 0 1 1 1 0 Putative peptidase (DUF1758) RVT_1 PF00078.22 CDI74248.1 - 7.9e-08 31.9 0.1 1.7e-07 30.8 0.1 1.6 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_3 PF13456.1 CDI74248.1 - 0.025 14.3 0.0 0.05 13.3 0.0 1.5 1 0 0 1 1 1 0 Reverse transcriptase-like TraT PF05818.7 CDI74253.1 - 0.00036 20.0 8.5 0.00049 19.5 5.9 1.2 1 0 0 1 1 1 1 Enterobacterial TraT complement resistance protein Activator_LAG-3 PF11498.3 CDI74253.1 - 0.0027 16.5 19.2 0.0036 16.1 13.3 1.2 1 0 0 1 1 1 1 Transcriptional activator LAG-3 FimP PF09766.4 CDI74253.1 - 0.025 13.6 14.3 0.033 13.2 9.9 1.1 1 0 0 1 1 1 0 Fms-interacting protein Ycf1 PF05758.7 CDI74253.1 - 0.13 9.9 4.7 0.14 9.8 3.2 1.0 1 0 0 1 1 1 0 Ycf1 UPF0560 PF10577.4 CDI74253.1 - 0.15 10.2 15.4 0.2 9.8 10.7 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 DUF4207 PF13904.1 CDI74253.1 - 0.46 9.8 24.0 0.67 9.2 16.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4207) PMSI1 PF15322.1 CDI74253.1 - 0.63 9.0 13.4 0.87 8.6 9.3 1.1 1 0 0 1 1 1 0 Protein missing in infertile sperm 1, putative FLO_LFY PF01698.11 CDI74253.1 - 1.9 7.2 15.0 2.5 6.8 10.4 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein Hid1 PF12722.2 CDI74253.1 - 2 6.0 7.8 2.3 5.7 5.4 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Pex16 PF08610.5 CDI74253.1 - 2.2 7.2 6.8 3 6.7 4.7 1.1 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) SID-1_RNA_chan PF13965.1 CDI74253.1 - 2.2 6.3 4.7 2.8 6.0 3.2 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Peptidase_S49_N PF08496.5 CDI74253.1 - 2.3 8.0 13.2 3.3 7.4 9.2 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF2215 PF10225.4 CDI74253.1 - 2.4 7.5 4.4 3.2 7.1 3.1 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) Draxin PF15550.1 CDI74253.1 - 2.5 7.6 14.2 3.6 7.1 9.9 1.1 1 0 0 1 1 1 0 Draxin PAT1 PF09770.4 CDI74253.1 - 3.3 5.8 34.2 3.8 5.6 23.7 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF2453 PF10507.4 CDI74253.1 - 3.7 7.4 4.2 6.4 6.6 2.9 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2453) Mlo PF03094.10 CDI74253.1 - 4.1 5.4 7.2 5.6 4.9 5.0 1.1 1 0 0 1 1 1 0 Mlo family Serinc PF03348.10 CDI74253.1 - 4.2 5.9 10.5 5.6 5.5 7.3 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) eIF-3_zeta PF05091.7 CDI74253.1 - 4.2 5.8 14.2 5.5 5.4 9.8 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) BTV_NS2 PF04514.7 CDI74253.1 - 5.4 5.7 12.6 8 5.2 8.7 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Parvo_coat PF00740.13 CDI74253.1 - 6.1 5.6 14.1 8 5.2 9.8 1.1 1 0 0 1 1 1 0 Parvovirus coat protein VP2 TMEM247 PF15444.1 CDI74253.1 - 6.4 6.5 8.9 16 5.2 6.2 1.7 1 0 0 1 1 1 0 Transmembrane protein 247 Suf PF05843.9 CDI74253.1 - 6.5 6.3 16.1 9.3 5.8 11.1 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) HemX PF04375.9 CDI74253.1 - 8 4.9 27.2 11 4.4 18.9 1.1 1 0 0 1 1 1 0 HemX R_equi_Vir PF05526.6 CDI74253.1 - 8.1 6.0 11.2 13 5.4 7.8 1.2 1 0 0 1 1 1 0 Rhodococcus equi virulence-associated protein BOP1NT PF08145.7 CDI74255.1 - 2.4e-06 27.5 0.1 2.4e-06 27.5 0.0 2.4 2 1 0 2 2 2 1 BOP1NT (NUC169) domain CAF-1_p150 PF11600.3 CDI74255.1 - 0.0053 16.1 12.8 0.0053 16.1 8.9 2.5 2 0 0 2 2 2 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal FimP PF09766.4 CDI74255.1 - 0.016 14.3 9.2 0.37 9.8 0.9 2.2 2 0 0 2 2 2 0 Fms-interacting protein 60KD_IMP PF02096.15 CDI74255.1 - 0.055 13.1 5.3 0.93 9.1 0.1 2.3 2 0 0 2 2 2 0 60Kd inner membrane protein DUF3801 PF12687.2 CDI74255.1 - 0.12 11.9 14.8 0.047 13.2 3.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3801) AIF_C PF14721.1 CDI74255.1 - 0.19 12.0 0.1 0.19 12.0 0.1 4.0 2 1 1 4 4 4 0 Apoptosis-inducing factor, mitochondrion-associated, C-term DUF3994 PF13159.1 CDI74255.1 - 0.64 10.3 13.0 8.8 6.6 3.7 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF3994) AAA_23 PF13476.1 CDI74255.1 - 1 9.6 12.4 0.59 10.4 0.6 2.2 2 0 0 2 2 2 0 AAA domain Neur_chan_memb PF02932.11 CDI74255.1 - 1.1 9.0 9.8 91 2.8 6.8 2.2 1 1 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Suf PF05843.9 CDI74255.1 - 1.5 8.4 20.6 0.99 9.0 0.7 2.7 2 1 0 2 2 2 0 Suppressor of forked protein (Suf) DUF2489 PF10675.4 CDI74255.1 - 2.2 7.9 22.4 0.61 9.7 3.8 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2489) NTP_transf_3 PF12804.2 CDI74255.1 - 3.5 7.6 13.9 85 3.1 9.6 2.3 1 1 0 1 1 1 0 MobA-like NTP transferase domain Rpp20 PF12328.3 CDI74255.1 - 8.6 6.0 10.4 13 5.4 1.3 3.1 3 0 0 3 3 3 0 Rpp20 subunit of nuclear RNase MRP and P dsDNA_bind PF01984.15 CDI74255.1 - 9.4 6.2 32.8 15 5.6 7.6 2.8 2 0 0 2 2 2 0 Double-stranded DNA-binding domain DUF2413 PF10310.4 CDI74256.1 - 5.2e-07 28.8 6.8 5.4e-07 28.7 4.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2413) DUF1183 PF06682.7 CDI74256.1 - 2.5e-06 27.3 7.2 3.1e-06 27.0 5.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1183) Zip PF02535.17 CDI74256.1 - 6.5e-06 25.3 1.2 8.8e-06 24.9 0.8 1.2 1 0 0 1 1 1 1 ZIP Zinc transporter DUF605 PF04652.11 CDI74256.1 - 4.8e-05 22.9 15.8 5.3e-05 22.8 11.0 1.1 1 0 0 1 1 1 1 Vta1 like SAGA-Tad1 PF12767.2 CDI74256.1 - 0.00029 20.5 11.8 0.00031 20.4 8.2 1.2 1 0 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit Med15 PF09606.5 CDI74256.1 - 0.0013 17.0 58.3 0.0015 16.8 40.4 1.1 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal SID-1_RNA_chan PF13965.1 CDI74256.1 - 0.0036 15.5 5.3 0.0042 15.3 3.7 1.1 1 0 0 1 1 1 1 dsRNA-gated channel SID-1 GAGA_bind PF06217.7 CDI74256.1 - 0.0074 16.2 13.6 0.0082 16.1 9.4 1.1 1 0 0 1 1 1 1 GAGA binding protein-like family DUF913 PF06025.7 CDI74256.1 - 0.0089 14.8 7.0 0.011 14.4 4.8 1.1 1 0 0 1 1 1 1 Domain of Unknown Function (DUF913) TRAP_alpha PF03896.11 CDI74256.1 - 0.014 14.4 1.7 0.021 13.8 1.2 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit HemX PF04375.9 CDI74256.1 - 0.014 13.9 30.9 0.019 13.6 21.4 1.1 1 0 0 1 1 1 0 HemX DUF2201_N PF13203.1 CDI74256.1 - 0.022 13.9 19.7 0.031 13.4 13.6 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain APG6 PF04111.7 CDI74256.1 - 0.026 13.5 22.4 0.033 13.2 15.6 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF1510 PF07423.6 CDI74256.1 - 0.027 13.8 23.3 0.036 13.4 16.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Neur_chan_memb PF02932.11 CDI74256.1 - 0.033 14.0 12.4 0.045 13.6 8.6 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DDHD PF02862.12 CDI74256.1 - 0.036 13.8 14.3 0.055 13.2 9.9 1.3 1 0 0 1 1 1 0 DDHD domain Ycf1 PF05758.7 CDI74256.1 - 0.04 11.6 19.1 0.052 11.2 13.2 1.0 1 0 0 1 1 1 0 Ycf1 CobT PF06213.7 CDI74256.1 - 0.051 12.7 13.5 0.061 12.4 9.4 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Potyvirid-P3 PF13608.1 CDI74256.1 - 0.079 12.0 13.2 0.095 11.7 9.1 1.1 1 0 0 1 1 1 0 Protein P3 of Potyviral polyprotein TFIIA PF03153.8 CDI74256.1 - 0.099 12.5 33.3 0.12 12.2 23.1 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Sec62 PF03839.11 CDI74256.1 - 0.1 12.0 11.9 0.13 11.6 8.2 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 Peroxin-13_N PF04088.8 CDI74256.1 - 0.12 12.3 11.1 0.31 10.9 0.5 2.2 1 1 1 2 2 2 0 Peroxin 13, N-terminal region SAPS PF04499.10 CDI74256.1 - 0.12 10.9 16.4 0.15 10.7 11.3 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Raftlin PF15250.1 CDI74256.1 - 0.13 10.7 17.1 0.16 10.4 11.8 1.1 1 0 0 1 1 1 0 Raftlin SelP_N PF04592.9 CDI74256.1 - 0.14 11.4 19.4 0.19 11.0 13.5 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region DUF3260 PF11658.3 CDI74256.1 - 0.14 10.2 11.4 0.17 9.9 7.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3260) RR_TM4-6 PF06459.7 CDI74256.1 - 0.16 11.8 20.5 0.21 11.4 14.2 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF4131 PF13567.1 CDI74256.1 - 0.2 11.0 6.1 0.29 10.5 3.9 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4131) IncA PF04156.9 CDI74256.1 - 0.2 11.2 40.0 0.47 10.0 27.8 1.6 1 1 0 1 1 1 0 IncA protein Mgr1 PF08602.5 CDI74256.1 - 0.31 10.0 4.9 0.33 9.9 3.4 1.1 1 0 0 1 1 1 0 Mgr1-like, i-AAA protease complex subunit UPF0233 PF06781.7 CDI74256.1 - 0.35 10.5 0.1 0.35 10.5 0.1 2.8 1 1 1 2 2 1 0 Uncharacterised protein family (UPF0233) Band_3_cyto PF07565.8 CDI74256.1 - 0.35 10.3 18.5 0.55 9.7 12.8 1.3 1 0 0 1 1 1 0 Band 3 cytoplasmic domain CDC45 PF02724.9 CDI74256.1 - 0.46 8.4 21.1 0.6 8.0 14.6 1.1 1 0 0 1 1 1 0 CDC45-like protein G-7-MTase PF12803.2 CDI74256.1 - 0.51 9.4 13.2 0.69 8.9 9.1 1.1 1 0 0 1 1 1 0 mRNA (guanine-7-)methyltransferase (G-7-MTase) HCO3_cotransp PF00955.16 CDI74256.1 - 0.55 8.8 4.1 0.71 8.4 2.8 1.2 1 0 0 1 1 1 0 HCO3- transporter family Ndc1_Nup PF09531.5 CDI74256.1 - 0.8 8.0 24.3 1.1 7.5 16.8 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup FAM60A PF15396.1 CDI74256.1 - 0.85 9.3 17.2 1.1 8.9 11.9 1.1 1 0 0 1 1 1 0 Protein Family FAM60A AvrE PF11725.3 CDI74256.1 - 0.96 6.3 19.4 1 6.2 13.5 1.0 1 0 0 1 1 1 0 Pathogenicity factor DUF4220 PF13968.1 CDI74256.1 - 1.1 8.2 7.8 1.4 7.9 5.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4220) Rtf2 PF04641.7 CDI74256.1 - 1.2 8.3 20.0 1.8 7.6 13.9 1.3 1 0 0 1 1 1 0 Rtf2 RING-finger DUF2407_C PF13373.1 CDI74256.1 - 1.5 8.7 13.5 2.1 8.2 8.9 1.5 1 1 1 2 2 2 0 DUF2407 C-terminal domain MMR1 PF08505.5 CDI74256.1 - 1.5 8.7 22.9 2.1 8.3 15.9 1.2 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein DUF2126 PF09899.4 CDI74256.1 - 1.7 6.5 11.0 2.3 6.1 7.6 1.2 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) DUF1675 PF07897.6 CDI74256.1 - 2 8.2 13.6 2.3 7.9 9.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) Cyto_heme_lyase PF01265.12 CDI74256.1 - 2 7.9 20.1 2.4 7.6 13.9 1.1 1 0 0 1 1 1 0 Cytochrome c/c1 heme lyase Herpes_UL87 PF03043.9 CDI74256.1 - 3.7 5.8 11.4 4.5 5.5 7.9 1.1 1 0 0 1 1 1 0 Herpesvirus UL87 family Tim54 PF11711.3 CDI74256.1 - 4.5 5.7 15.2 7 5.1 10.5 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 CemA PF03040.9 CDI74256.1 - 5.1 6.6 7.9 6.2 6.3 5.5 1.1 1 0 0 1 1 1 0 CemA family Herpes_DNAp_acc PF04929.7 CDI74256.1 - 6.2 5.6 21.1 8 5.3 14.7 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor VID27 PF08553.5 CDI74256.1 - 6.9 4.7 15.0 8.2 4.5 10.4 1.0 1 0 0 1 1 1 0 VID27 cytoplasmic protein DUF912 PF06024.7 CDI74256.1 - 9.2 6.3 19.2 0.25 11.4 2.2 2.3 1 1 1 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DNA_pack_N PF02500.10 CDI74256.1 - 9.2 5.7 15.6 13 5.2 10.8 1.1 1 0 0 1 1 1 0 Probable DNA packing protein, N-terminus Cellulose_synt PF03552.9 CDI74256.1 - 9.6 4.3 10.4 14 3.8 7.2 1.3 1 0 0 1 1 1 0 Cellulose synthase Syja_N PF02383.13 CDI74257.1 - 8.2e-18 64.2 15.4 1.8e-17 63.0 4.5 3.5 3 2 0 3 3 3 2 SacI homology domain SR-25 PF10500.4 CDI74257.1 - 5.6e-05 22.7 13.3 5.6e-05 22.7 9.2 6.6 6 1 0 6 6 6 3 Nuclear RNA-splicing-associated protein DUF2040 PF09745.4 CDI74257.1 - 0.00086 19.1 1.0 0.00086 19.1 0.7 5.9 6 0 0 6 6 6 1 Coiled-coil domain-containing protein 55 (DUF2040) Pentapeptide_4 PF13599.1 CDI74260.1 - 2e-13 49.9 0.1 6.3e-05 22.7 0.0 3.5 1 1 0 1 1 1 1 Pentapeptide repeats (9 copies) CDK2AP PF09806.4 CDI74261.1 - 0.0029 17.8 11.0 0.0029 17.8 7.6 2.1 2 0 0 2 2 2 1 Cyclin-dependent kinase 2-associated protein DUF1180 PF06679.7 CDI74261.1 - 0.0047 16.8 10.6 0.029 14.2 2.6 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1180) RskA PF10099.4 CDI74261.1 - 0.0056 16.4 7.4 0.0056 16.4 5.2 2.1 1 1 1 2 2 2 1 Anti-sigma-K factor rskA Med15 PF09606.5 CDI74261.1 - 0.038 12.1 33.3 0.045 11.9 23.1 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal HemX PF04375.9 CDI74261.1 - 0.071 11.6 25.1 0.098 11.2 17.4 1.2 1 0 0 1 1 1 0 HemX MRP-S31 PF15433.1 CDI74261.1 - 0.096 12.0 22.3 0.12 11.7 15.4 1.1 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 PAT1 PF09770.4 CDI74261.1 - 0.13 10.5 29.6 0.15 10.3 20.5 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF3357 PF11837.3 CDI74261.1 - 0.25 11.1 19.3 0.13 12.1 2.6 3.2 1 1 2 3 3 3 0 Domain of unknown function (DUF3357) DUF2899 PF11449.3 CDI74261.1 - 0.42 9.7 2.3 0.52 9.4 1.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2899) EphA2_TM PF14575.1 CDI74261.1 - 0.44 10.9 15.6 0.44 10.9 0.8 3.0 1 1 2 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain TFIIA PF03153.8 CDI74261.1 - 0.62 9.9 34.8 0.89 9.3 24.2 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Peptidase_S49_N PF08496.5 CDI74261.1 - 0.88 9.3 10.6 1.7 8.4 7.4 1.5 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF106 PF01956.11 CDI74261.1 - 4.5 6.7 8.8 7.5 6.0 6.1 1.4 1 0 0 1 1 1 0 Integral membrane protein DUF106 Nop25 PF09805.4 CDI74261.1 - 5.3 7.1 17.4 2.1 8.4 9.9 1.8 2 0 0 2 2 2 0 Nucleolar protein 12 (25kDa) DUF2615 PF11027.3 CDI74261.1 - 6.7 6.7 10.8 4.1 7.3 3.7 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2615) FCP1_C PF09309.5 CDI74262.1 - 0.0032 16.8 5.9 0.0032 16.8 4.1 6.8 7 1 0 7 7 7 2 FCP1, C-terminal Med15 PF09606.5 CDI74262.1 - 0.035 12.3 142.5 0.018 13.2 53.1 4.0 4 0 0 4 4 4 0 ARC105 or Med15 subunit of Mediator complex non-fungal N6_N4_Mtase PF01555.13 CDI74262.1 - 0.1 12.0 0.0 99 2.3 0.0 3.3 3 1 0 3 3 3 0 DNA methylase PNTB PF02233.11 CDI74263.1 - 1.2e-153 512.2 28.1 3.6e-92 309.5 1.3 2.7 2 1 1 3 3 3 2 NAD(P) transhydrogenase beta subunit AlaDh_PNT_C PF01262.16 CDI74263.1 - 1.2e-41 142.0 0.4 2.3e-41 141.1 0.3 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N PF05222.10 CDI74263.1 - 1.3e-21 77.0 0.0 2.4e-21 76.1 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain 2-Hacid_dh_C PF02826.14 CDI74263.1 - 2.9e-07 29.8 0.0 6e-07 28.7 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TPP_enzyme_M PF00205.17 CDI74263.1 - 0.00014 21.6 0.2 0.001 18.8 0.0 2.6 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain Shikimate_DH PF01488.15 CDI74263.1 - 0.0069 16.4 0.2 0.036 14.1 0.1 2.3 2 1 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Yqai PF09466.5 CDI74263.1 - 0.045 13.7 0.0 16 5.5 0.0 2.5 2 0 0 2 2 2 0 Hypothetical protein Yqai Pyr_redox_2 PF07992.9 CDI74263.1 - 0.078 12.8 0.2 0.18 11.6 0.1 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Methyltransf_31 PF13847.1 CDI74263.1 - 0.084 12.4 0.0 0.19 11.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain DUF2325 PF10087.4 CDI74263.1 - 0.11 12.4 0.0 0.28 11.0 0.0 1.7 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2325) DUF3814 PF12769.2 CDI74263.1 - 0.31 11.2 23.9 0.023 14.8 5.9 5.6 3 2 2 5 5 5 0 Domain of unknown function (DUF3814) DUF4559 PF15112.1 CDI74264.1 - 0.96 8.5 2.7 2.2 7.3 1.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) SNF2_N PF00176.18 CDI74265.1 - 1.7e-27 96.0 2.7 1.5e-14 53.5 0.0 3.3 2 1 1 3 3 3 3 SNF2 family N-terminal domain Helicase_C PF00271.26 CDI74265.1 - 7.1e-07 29.0 0.0 7.1e-07 29.0 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Ycf1 PF05758.7 CDI74265.1 - 0.0093 13.7 1.4 0.013 13.2 1.0 1.1 1 0 0 1 1 1 1 Ycf1 Serinc PF03348.10 CDI74265.1 - 0.039 12.6 2.5 0.064 11.9 1.7 1.3 1 0 0 1 1 1 0 Serine incorporator (Serinc) FimP PF09766.4 CDI74265.1 - 2.5 7.1 20.7 4.8 6.1 14.3 1.4 1 0 0 1 1 1 0 Fms-interacting protein Mem_trans PF03547.13 CDI74265.1 - 3.7 5.7 4.1 0.5 8.6 0.1 1.7 2 0 0 2 2 2 0 Membrane transport protein Melibiase PF02065.13 CDI74266.1 - 0.074 11.7 0.0 0.17 10.5 0.0 1.4 1 1 0 1 1 1 0 Melibiase DUF2217 PF10265.4 CDI74266.1 - 0.31 9.7 6.4 2.8 6.6 5.5 1.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2217) Macoilin PF09726.4 CDI74266.1 - 0.37 9.0 23.3 0.6 8.3 16.1 1.2 1 0 0 1 1 1 0 Transmembrane protein DUF572 PF04502.8 CDI74266.1 - 4.6 6.3 9.4 10 5.1 6.5 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF572) Apt1 PF10351.4 CDI74266.1 - 5.4 5.7 13.7 8.9 5.0 9.5 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain Shadoo PF14999.1 CDI74267.1 - 0.0017 18.2 1.4 0.0021 17.8 1.0 1.2 1 0 0 1 1 1 1 Shadow of prion protein, neuroprotective Med15 PF09606.5 CDI74267.1 - 0.35 9.0 76.7 0.4 8.8 53.2 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal PAT1 PF09770.4 CDI74267.1 - 0.56 8.3 60.9 0.64 8.1 42.2 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 CDK5_activator PF03261.10 CDI74267.1 - 0.93 8.7 21.0 1.5 8.0 14.6 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein GAGA_bind PF06217.7 CDI74267.1 - 5.8 6.7 27.3 6.6 6.6 18.9 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family NMT PF01233.14 CDI74270.1 - 2.1e-05 24.1 0.0 2.9e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain zf-C4H2 PF10146.4 CDI74270.1 - 2.7 7.9 5.7 3.7 7.5 3.9 1.2 1 0 0 1 1 1 0 Zinc finger-containing protein Med3 PF11593.3 CDI74270.1 - 4.5 6.4 11.4 4.7 6.3 7.9 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal PAT1 PF09770.4 CDI74272.1 - 9.5e-05 20.8 51.3 0.0001 20.7 35.5 1.0 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 CDC27 PF09507.5 CDI74272.1 - 0.00012 21.4 38.4 0.00013 21.3 26.6 1.1 1 0 0 1 1 1 1 DNA polymerase subunit Cdc27 Med15 PF09606.5 CDI74272.1 - 0.00049 18.4 62.6 0.00064 18.0 43.4 1.2 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal SR-25 PF10500.4 CDI74272.1 - 0.0079 15.6 39.6 0.0079 15.6 27.4 2.3 1 1 1 2 2 2 1 Nuclear RNA-splicing-associated protein DUF4603 PF15376.1 CDI74272.1 - 1.4 5.9 33.9 2.1 5.4 23.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) ODV-E18 PF10717.4 CDI74272.1 - 6.6 6.2 11.6 0.52 9.7 2.2 2.7 2 1 1 3 3 3 0 Occlusion-derived virus envelope protein ODV-E18 Nucleo_P87 PF07267.6 CDI74272.1 - 8.3 4.9 44.6 11 4.5 30.9 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 RAB3GAP2_N PF14655.1 CDI74273.1 - 0.18 10.7 7.3 0.18 10.7 0.3 2.3 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus SOBP PF15279.1 CDI74273.1 - 0.24 11.7 9.4 0.43 10.9 0.5 2.4 2 0 0 2 2 2 0 Sine oculis-binding protein DUF2681 PF10883.3 CDI74273.1 - 1.4 9.1 14.4 0.77 9.9 1.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) FimP PF09766.4 CDI74273.1 - 2.8 6.9 11.0 1.3 7.9 1.2 2.1 2 0 0 2 2 2 0 Fms-interacting protein Phostensin_N PF13916.1 CDI74273.1 - 3.7 7.5 13.6 3.3 7.7 0.5 2.5 2 0 0 2 2 2 0 PP1-regulatory protein, Phostensin N-terminal DivIC PF04977.10 CDI74273.1 - 4.2 6.9 13.5 1.9 8.0 1.6 2.2 2 0 0 2 2 2 0 Septum formation initiator Daxx PF03344.10 CDI74274.1 - 0.45 8.9 58.4 0.73 8.2 40.5 1.2 1 0 0 1 1 1 0 Daxx Family SpoIIIAH PF12685.2 CDI74275.1 - 1.7 8.1 6.4 5.9 6.3 4.4 1.8 1 1 0 1 1 1 0 SpoIIIAH-like protein Pex14_N PF04695.8 CDI74276.1 - 7.8e-05 22.7 18.8 0.00018 21.5 3.2 2.2 2 0 0 2 2 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Plasmodium_Vir PF05795.6 CDI74276.1 - 0.0021 17.3 2.5 0.0027 16.9 1.7 1.1 1 0 0 1 1 1 1 Plasmodium vivax Vir protein SR-25 PF10500.4 CDI74276.1 - 0.0048 16.4 27.0 0.026 13.9 8.0 2.3 2 0 0 2 2 2 2 Nuclear RNA-splicing-associated protein Med15 PF09606.5 CDI74276.1 - 0.0073 14.5 20.4 0.01 14.1 14.2 1.2 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal Ycf1 PF05758.7 CDI74276.1 - 0.01 13.5 5.4 0.012 13.3 3.7 1.1 1 0 0 1 1 1 0 Ycf1 PRCC PF10253.4 CDI74276.1 - 0.03 15.0 11.4 0.03 15.0 7.9 2.2 2 0 0 2 2 2 0 Mitotic checkpoint regulator, MAD2B-interacting Macoilin PF09726.4 CDI74276.1 - 0.059 11.6 21.7 0.076 11.2 15.1 1.1 1 0 0 1 1 1 0 Transmembrane protein DUF3260 PF11658.3 CDI74276.1 - 0.099 10.7 7.1 0.18 9.8 4.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3260) DDRGK PF09756.4 CDI74276.1 - 0.16 11.3 14.4 0.28 10.5 10.0 1.3 1 0 0 1 1 1 0 DDRGK domain FAM117 PF15388.1 CDI74276.1 - 0.17 11.0 28.9 0.27 10.4 20.0 1.2 1 1 0 1 1 1 0 Protein Family FAM117 XAP5 PF04921.9 CDI74276.1 - 0.36 10.3 10.6 2.7 7.4 4.9 2.1 2 0 0 2 2 2 0 XAP5, circadian clock regulator SprA-related PF12118.3 CDI74276.1 - 0.39 9.9 38.0 0.18 11.1 15.8 2.2 2 0 0 2 2 2 0 SprA-related family CD20 PF04103.10 CDI74276.1 - 0.59 10.0 4.5 1.2 9.0 0.3 2.2 2 0 0 2 2 2 0 CD20-like family FemAB PF02388.11 CDI74276.1 - 0.65 8.6 13.1 1.1 7.8 9.1 1.3 1 0 0 1 1 1 0 FemAB family TFIIA PF03153.8 CDI74276.1 - 1.1 9.0 28.7 0.18 11.6 11.1 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Gti1_Pac2 PF09729.4 CDI74276.1 - 1.2 9.0 10.7 0.58 10.0 1.4 2.1 2 0 0 2 2 2 0 Gti1/Pac2 family Apc15p PF05841.6 CDI74276.1 - 1.2 9.8 20.7 2.5 8.8 5.0 2.5 2 0 0 2 2 2 0 Apc15p protein Maf1 PF09174.5 CDI74276.1 - 1.2 8.9 13.5 0.79 9.5 1.4 2.1 2 0 0 2 2 2 0 Maf1 regulator DUF506 PF04720.7 CDI74276.1 - 1.5 8.4 13.8 1.6 8.3 1.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF506) FimP PF09766.4 CDI74276.1 - 1.6 7.7 19.4 0.067 12.2 9.5 1.6 2 0 0 2 2 2 0 Fms-interacting protein DUF912 PF06024.7 CDI74276.1 - 1.7 8.7 9.6 2.2 8.3 3.7 2.3 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Vfa1 PF08432.5 CDI74276.1 - 2.1 8.3 17.1 0.64 10.0 7.0 2.1 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 FGGY_N PF00370.16 CDI74276.1 - 2.3 7.4 8.0 7.2 5.8 5.4 1.8 2 0 0 2 2 2 0 FGGY family of carbohydrate kinases, N-terminal domain DDHD PF02862.12 CDI74276.1 - 2.6 7.7 18.7 1.6 8.4 5.9 2.2 2 0 0 2 2 2 0 DDHD domain DUF4337 PF14235.1 CDI74276.1 - 2.7 7.8 19.8 0.42 10.4 10.5 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) Asp-B-Hydro_N PF05279.6 CDI74276.1 - 2.7 7.7 13.7 5 6.8 9.5 1.4 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region POX PF07526.6 CDI74276.1 - 3 8.0 16.9 7.7 6.7 1.1 2.3 2 0 0 2 2 2 0 Associated with HOX eIF3_subunit PF08597.5 CDI74276.1 - 4.4 6.7 20.1 2.3 7.7 12.9 1.5 1 1 0 1 1 1 0 Translation initiation factor eIF3 subunit FAM60A PF15396.1 CDI74276.1 - 4.5 6.9 15.5 3.7 7.2 4.4 2.2 2 0 0 2 2 2 0 Protein Family FAM60A Zip PF02535.17 CDI74276.1 - 5.3 5.9 9.8 2.7 6.9 2.5 2.0 2 0 0 2 2 2 0 ZIP Zinc transporter DUF1510 PF07423.6 CDI74276.1 - 5.8 6.2 20.4 2.4 7.4 11.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) Rtf2 PF04641.7 CDI74276.1 - 6.2 5.9 20.4 0.23 10.6 7.5 2.1 2 0 0 2 2 2 0 Rtf2 RING-finger Suf PF05843.9 CDI74276.1 - 7.8 6.1 18.3 0.89 9.2 6.3 2.1 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) TCP PF03634.8 CDI74276.1 - 9.1 6.6 26.9 10 6.5 7.6 2.2 2 0 0 2 2 2 0 TCP family transcription factor DUF3449 PF11931.3 CDI74276.1 - 9.6 5.6 14.3 8.7 5.8 7.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3449) TSP_1 PF00090.14 CDI74277.1 - 0.0055 16.7 15.2 0.031 14.4 0.6 4.5 3 0 0 3 3 3 3 Thrombospondin type 1 domain SPX PF03105.14 CDI74278.1 - 0.0032 17.3 12.9 0.0032 17.3 9.0 4.3 3 2 0 3 3 3 1 SPX domain IncA PF04156.9 CDI74281.1 - 0.0016 18.1 7.9 0.0033 17.0 5.5 1.5 1 0 0 1 1 1 1 IncA protein CDC27 PF09507.5 CDI74281.1 - 0.0039 16.4 16.2 0.0045 16.2 11.2 1.1 1 0 0 1 1 1 1 DNA polymerase subunit Cdc27 Med15 PF09606.5 CDI74281.1 - 0.0041 15.3 35.9 0.0055 14.9 24.9 1.2 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal zf-DHHC PF01529.15 CDI74281.1 - 0.031 13.6 0.2 0.033 13.5 0.1 1.1 1 0 0 1 1 1 0 DHHC palmitoyltransferase RR_TM4-6 PF06459.7 CDI74281.1 - 0.057 13.2 12.8 0.067 13.0 8.9 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 FimP PF09766.4 CDI74281.1 - 0.096 11.7 13.1 0.13 11.2 9.1 1.2 1 0 0 1 1 1 0 Fms-interacting protein DUF4557 PF15101.1 CDI74281.1 - 0.38 10.5 15.3 0.61 9.8 10.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) DUF2052 PF09747.4 CDI74281.1 - 0.52 10.2 20.8 0.77 9.6 14.4 1.2 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) PAT1 PF09770.4 CDI74281.1 - 0.78 7.8 26.4 0.91 7.6 18.3 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Serinc PF03348.10 CDI74281.1 - 0.92 8.1 7.5 1 8.0 5.2 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) Asp-B-Hydro_N PF05279.6 CDI74281.1 - 1.6 8.5 11.0 2.4 7.9 7.6 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Parvo_coat PF00740.13 CDI74281.1 - 1.6 7.5 11.3 1.8 7.4 7.8 1.1 1 0 0 1 1 1 0 Parvovirus coat protein VP2 DUF2215 PF10225.4 CDI74281.1 - 2 7.7 6.0 2.7 7.3 4.2 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) TFIIA PF03153.8 CDI74281.1 - 2.2 8.0 33.2 3 7.6 23.0 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit BTV_NS2 PF04514.7 CDI74281.1 - 2.2 7.0 9.6 2.9 6.6 6.7 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 DUF1510 PF07423.6 CDI74281.1 - 2.4 7.4 15.4 3.6 6.8 10.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) LMBR1 PF04791.11 CDI74281.1 - 2.6 6.5 6.7 3.5 6.1 4.6 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Suf PF05843.9 CDI74281.1 - 2.7 7.6 11.9 3.4 7.3 8.2 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) FLO_LFY PF01698.11 CDI74281.1 - 3.6 6.3 13.8 4.7 5.9 9.5 1.2 1 0 0 1 1 1 0 Floricaula / Leafy protein AAA_23 PF13476.1 CDI74281.1 - 4.1 7.6 9.9 5.4 7.2 6.9 1.1 1 0 0 1 1 1 0 AAA domain Ycf1 PF05758.7 CDI74281.1 - 5.7 4.5 12.1 6.9 4.2 8.4 1.0 1 0 0 1 1 1 0 Ycf1 Pilt PF15453.1 CDI74281.1 - 6.1 6.4 24.1 9.2 5.8 16.7 1.2 1 0 0 1 1 1 0 Protein incorporated later into Tight Junctions AUX_IAA PF02309.11 CDI74281.1 - 8.7 6.0 11.8 12 5.5 8.2 1.3 1 0 0 1 1 1 0 AUX/IAA family APG6 PF04111.7 CDI74281.1 - 9.1 5.2 17.6 13 4.7 12.2 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 HTH_15 PF12324.3 CDI74282.1 - 0.13 11.9 1.1 0.25 11.0 0.1 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain of alkylmercury lyase RVT_1 PF00078.22 CDI74283.1 - 0.00037 19.9 0.0 0.0011 18.3 0.0 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) ELYS PF13934.1 CDI74283.1 - 0.03 14.0 0.1 0.5 10.0 0.1 2.0 1 1 0 1 1 1 0 Nuclear pore complex assembly K_trans PF02705.11 CDI74284.1 - 0.74 8.0 2.8 0.97 7.7 1.9 1.3 1 0 0 1 1 1 0 K+ potassium transporter PAT1 PF09770.4 CDI74284.1 - 0.84 7.8 66.1 1.1 7.3 45.8 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 N6_N4_Mtase PF01555.13 CDI74285.1 - 1.9e-05 24.2 0.0 3.9 6.9 0.0 7.7 9 2 0 9 9 9 1 DNA methylase Spore_coat_CotO PF14153.1 CDI74285.1 - 4.4e-05 22.9 9.2 4.4e-05 22.9 6.4 21.5 21 3 0 23 23 23 4 Spore coat protein CotO PspB PF06667.7 CDI74286.1 - 0.02 14.7 1.8 0.02 14.7 1.3 2.2 2 0 0 2 2 2 0 Phage shock protein B PAT1 PF09770.4 CDI74286.1 - 0.35 9.0 35.7 0.56 8.3 24.7 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Chromo PF00385.19 CDI74287.1 - 4.1e-12 45.5 0.0 7.1e-12 44.8 0.0 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Cyclin PF08613.6 CDI74288.1 - 1.6e-19 70.8 0.0 7.3e-19 68.6 0.0 2.3 1 0 0 1 1 1 1 Cyclin Neur_chan_memb PF02932.11 CDI74288.1 - 5.7 6.7 22.9 0.17 11.7 1.0 4.4 2 2 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region SR-25 PF10500.4 CDI74290.1 - 0.0089 15.5 4.3 0.011 15.2 3.0 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein BSP_II PF05432.6 CDI74290.1 - 0.015 14.5 11.6 0.017 14.4 8.0 1.1 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) CobT PF06213.7 CDI74290.1 - 0.5 9.4 19.6 0.61 9.1 13.6 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT SpoIIIAH PF12685.2 CDI74290.1 - 0.66 9.4 7.1 0.81 9.1 4.9 1.1 1 0 0 1 1 1 0 SpoIIIAH-like protein DUF2735 PF10931.3 CDI74290.1 - 0.7 10.1 4.1 1.9 8.7 2.8 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2735) DUF2201_N PF13203.1 CDI74290.1 - 1 8.4 8.8 1.2 8.1 6.1 1.0 1 0 0 1 1 1 0 Putative metallopeptidase domain CDC45 PF02724.9 CDI74290.1 - 1.1 7.2 7.7 1.3 6.9 5.4 1.1 1 0 0 1 1 1 0 CDC45-like protein Myc_N PF01056.13 CDI74290.1 - 1.6 7.8 11.2 1.9 7.5 7.8 1.2 1 0 0 1 1 1 0 Myc amino-terminal region DUF2457 PF10446.4 CDI74290.1 - 2.3 6.8 10.5 2.8 6.5 7.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Sporozoite_P67 PF05642.6 CDI74290.1 - 2.8 5.7 7.1 3.2 5.4 4.9 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen TRAP_alpha PF03896.11 CDI74290.1 - 3.9 6.4 6.4 4.5 6.1 4.5 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit BUD22 PF09073.5 CDI74290.1 - 4.2 6.3 12.8 5 6.0 8.9 1.1 1 0 0 1 1 1 0 BUD22 Pox_RNA_Pol_19 PF05320.7 CDI74290.1 - 7.7 6.2 6.3 10 5.8 4.4 1.3 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit DUF1510 PF07423.6 CDI74290.1 - 9.9 5.4 11.4 13 5.1 7.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) NicO PF03824.11 CDI74291.1 - 0.99 8.6 4.1 1.6 8.0 2.8 1.2 1 0 0 1 1 1 0 High-affinity nickel-transport protein Suf PF05843.9 CDI74293.1 - 0.3 10.7 4.0 0.47 10.1 2.8 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) FimP PF09766.4 CDI74293.1 - 0.65 8.9 11.0 0.93 8.4 7.6 1.1 1 0 0 1 1 1 0 Fms-interacting protein DUF3987 PF13148.1 CDI74294.1 - 1.3 7.4 8.9 1.4 7.3 6.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) Hid1 PF12722.2 CDI74297.1 - 3.5 5.1 40.6 1.4 6.4 15.9 2.1 2 0 0 2 2 2 0 High-temperature-induced dauer-formation protein Nha1_C PF08619.5 CDI74297.1 - 7.1 5.7 34.9 0.44 9.7 13.9 2.2 2 0 0 2 2 2 0 Alkali metal cation/H+ antiporter Nha1 C terminus PX PF00787.19 CDI74298.1 - 4.7e-15 55.3 0.0 1.4e-14 53.8 0.0 1.8 1 0 0 1 1 1 1 PX domain HlyD_2 PF12700.2 CDI74298.1 - 0.0036 16.4 5.5 0.0036 16.4 3.8 2.5 2 1 0 2 2 2 1 HlyD family secretion protein Syja_N PF02383.13 CDI74299.1 - 3.6e-15 55.5 12.4 1e-09 37.6 2.1 3.5 3 1 0 3 3 3 2 SacI homology domain Tau95 PF09734.4 CDI74299.1 - 0.0003 20.2 7.4 0.00099 18.5 2.5 2.1 2 0 0 2 2 2 1 RNA polymerase III transcription factor (TF)IIIC subunit Spt20 PF12090.3 CDI74299.1 - 0.0012 18.2 32.5 0.089 12.1 3.1 3.4 3 0 0 3 3 3 3 Spt20 family Suf PF05843.9 CDI74299.1 - 0.0024 17.6 5.3 0.0024 17.6 3.7 3.6 4 0 0 4 4 4 2 Suppressor of forked protein (Suf) zf-DHHC PF01529.15 CDI74299.1 - 0.0055 16.1 10.4 0.54 9.6 0.1 3.3 3 0 0 3 3 3 2 DHHC palmitoyltransferase DUF2722 PF10846.3 CDI74299.1 - 0.016 14.2 0.3 0.016 14.2 0.2 4.4 4 2 1 5 5 1 0 Protein of unknown function (DUF2722) Band_3_cyto PF07565.8 CDI74299.1 - 0.12 11.8 29.4 0.74 9.2 2.6 3.2 3 0 0 3 3 3 0 Band 3 cytoplasmic domain FimP PF09766.4 CDI74299.1 - 0.16 10.9 54.0 0.053 12.5 8.8 3.1 3 0 0 3 3 3 0 Fms-interacting protein DcpS_C PF11969.3 CDI74299.1 - 0.17 12.1 4.4 2.6 8.2 0.3 2.4 2 0 0 2 2 2 0 Scavenger mRNA decapping enzyme C-term binding Dala_Dala_lig_N PF01820.16 CDI74299.1 - 0.63 10.3 15.0 0.95 9.7 0.3 3.6 3 0 0 3 3 3 0 D-ala D-ala ligase N-terminus AAA_23 PF13476.1 CDI74299.1 - 0.89 9.8 38.8 0.2 11.9 4.1 3.1 3 0 0 3 3 3 0 AAA domain RED_N PF07808.8 CDI74299.1 - 0.89 8.7 48.9 0.018 14.2 1.5 3.3 3 0 0 3 3 3 0 RED-like protein N-terminal region SPX PF03105.14 CDI74299.1 - 0.92 9.2 24.9 1.2 8.8 2.0 2.8 2 1 0 2 2 2 0 SPX domain EPL1 PF10513.4 CDI74299.1 - 3.2 7.9 25.0 2.5 8.3 2.6 3.4 3 0 0 3 3 3 0 Enhancer of polycomb-like DUF1510 PF07423.6 CDI74299.1 - 5.5 6.2 29.3 0.18 11.1 2.2 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1510) DUF4647 PF15504.1 CDI74299.1 - 5.8 5.6 40.5 0.087 11.6 2.6 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4647) Folate_carrier PF01770.13 CDI74299.1 - 7.2 5.0 18.9 3 6.2 0.3 3.2 3 0 0 3 3 3 0 Reduced folate carrier Serinc PF03348.10 CDI74299.1 - 8 5.0 28.1 2.9 6.5 1.4 3.1 3 0 0 3 3 3 0 Serine incorporator (Serinc) DUF3371 PF11851.3 CDI74299.1 - 8.2 7.1 51.3 9.9 6.8 8.9 3.9 3 0 0 3 3 3 0 Domain of unknown function (DUF3371) YajC PF02699.10 CDI74300.1 - 8.6 6.1 7.6 17 5.2 5.3 1.4 1 0 0 1 1 1 0 Preprotein translocase subunit DUF3742 PF12553.3 CDI74301.1 - 3.7 8.0 0.0 3.7 8.0 0.0 4.9 5 0 0 5 5 5 0 Protein of unknown function (DUF3742) Herpes_UL52 PF03121.10 CDI74302.1 - 0.00026 20.6 0.1 0.00037 20.1 0.0 1.2 1 0 0 1 1 1 1 Herpesviridae UL52/UL70 DNA primase SAPS PF04499.10 CDI74302.1 - 0.16 10.5 1.3 0.2 10.2 0.9 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Daxx PF03344.10 CDI74302.1 - 2.2 6.6 5.7 2.4 6.5 4.0 1.2 1 0 0 1 1 1 0 Daxx Family Nop14 PF04147.7 CDI74302.1 - 2.6 5.8 7.7 2.7 5.7 5.3 1.1 1 0 0 1 1 1 0 Nop14-like family MIP-T3 PF10243.4 CDI74303.1 - 4.5e-05 22.1 9.6 4.5e-05 22.1 6.7 3.0 2 1 0 2 2 2 1 Microtubule-binding protein MIP-T3 CD20 PF04103.10 CDI74303.1 - 0.81 9.5 0.0 0.81 9.5 0.0 4.4 4 2 0 4 4 4 0 CD20-like family Radial_spoke PF04712.7 CDI74303.1 - 2.2 6.9 27.6 0.38 9.4 4.4 2.3 2 0 0 2 2 2 0 Radial spokehead-like protein Band_3_cyto PF07565.8 CDI74303.1 - 5.3 6.4 34.2 2.8 7.3 5.0 3.4 3 0 0 3 3 3 0 Band 3 cytoplasmic domain Pox_Ag35 PF03286.9 CDI74304.1 - 0.012 15.0 15.8 0.016 14.7 11.0 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein SAPS PF04499.10 CDI74304.1 - 0.021 13.4 20.0 0.025 13.2 13.9 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein CDC45 PF02724.9 CDI74304.1 - 0.084 10.9 19.6 0.092 10.7 13.6 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF1510 PF07423.6 CDI74304.1 - 0.1 11.9 25.1 0.12 11.6 17.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DUF4045 PF13254.1 CDI74304.1 - 0.11 11.7 23.0 0.13 11.5 16.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) eIF-3_zeta PF05091.7 CDI74304.1 - 0.13 10.8 26.3 0.15 10.6 18.2 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Raftlin PF15250.1 CDI74304.1 - 0.31 9.5 20.4 0.34 9.3 14.1 1.1 1 0 0 1 1 1 0 Raftlin SMN PF06003.7 CDI74304.1 - 0.31 10.0 8.0 0.39 9.7 5.5 1.1 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) Caldesmon PF02029.10 CDI74304.1 - 0.48 8.7 20.7 0.64 8.3 14.3 1.1 1 0 0 1 1 1 0 Caldesmon RNA_pol_Rpb1_5 PF04998.12 CDI74304.1 - 0.6 9.3 13.0 0.62 9.2 9.0 1.2 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 Strabismus PF06638.6 CDI74304.1 - 0.62 8.2 10.1 0.75 8.0 7.0 1.1 1 0 0 1 1 1 0 Strabismus protein FAM91_C PF14648.1 CDI74304.1 - 0.64 8.7 9.1 0.65 8.7 6.3 1.2 1 0 0 1 1 1 0 FAM91 C-terminus Glyco_transf_6 PF03414.8 CDI74304.1 - 1.1 7.6 11.5 1.3 7.4 7.9 1.3 1 0 0 1 1 1 0 Glycosyltransferase family 6 SpoVR PF04293.8 CDI74304.1 - 1.2 7.3 20.6 1.4 7.1 14.3 1.2 1 0 0 1 1 1 0 SpoVR like protein Hid1 PF12722.2 CDI74304.1 - 1.2 6.6 30.5 1.5 6.4 21.2 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF966 PF06136.8 CDI74304.1 - 1.3 8.3 19.9 1.5 8.1 13.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF966) TT_ORF1 PF02956.9 CDI74304.1 - 1.5 7.1 20.8 1.5 7.2 14.5 1.1 1 0 0 1 1 1 0 TT viral orf 1 Spore_YhcN_YlaJ PF09580.5 CDI74304.1 - 1.6 8.8 21.2 2 8.4 14.7 1.3 1 0 0 1 1 1 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) Tim54 PF11711.3 CDI74304.1 - 1.6 7.2 18.2 1.9 6.9 12.6 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Presenilin PF01080.12 CDI74304.1 - 1.7 7.4 15.0 1.8 7.2 10.4 1.2 1 0 0 1 1 1 0 Presenilin DUF2126 PF09899.4 CDI74304.1 - 2.1 6.2 14.4 2.1 6.3 10.0 1.2 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) GAGA_bind PF06217.7 CDI74304.1 - 2.4 8.0 22.7 2.7 7.8 15.7 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family DUF2228 PF10228.4 CDI74304.1 - 2.6 7.5 15.6 3.4 7.1 10.8 1.2 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2228) Plasmodium_Vir PF05795.6 CDI74304.1 - 2.7 7.1 10.8 3.3 6.8 7.5 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Herpes_env PF01673.13 CDI74304.1 - 2.7 6.4 17.2 3.1 6.2 12.0 1.2 1 0 0 1 1 1 0 Herpesvirus putative major envelope glycoprotein DHHW PF14286.1 CDI74304.1 - 3.2 6.9 18.4 3.5 6.8 12.7 1.1 1 0 0 1 1 1 0 DHHW protein Otopetrin PF03189.8 CDI74304.1 - 4.5 6.1 11.0 5.6 5.8 7.6 1.3 1 0 0 1 1 1 0 Otopetrin Paramyxo_ncap PF00973.14 CDI74304.1 - 5 5.7 19.2 5 5.6 13.3 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Adaptin_binding PF10199.4 CDI74304.1 - 5.7 7.2 29.9 8.6 6.6 20.7 1.3 1 0 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 Cellulose_synt PF03552.9 CDI74304.1 - 5.7 5.1 12.0 6 5.0 8.3 1.1 1 0 0 1 1 1 0 Cellulose synthase Peptidase_S64 PF08192.6 CDI74304.1 - 5.8 5.1 21.1 6.2 5.0 14.6 1.0 1 0 0 1 1 1 0 Peptidase family S64 DUF2828 PF11443.3 CDI74304.1 - 6.1 4.9 17.5 7.2 4.6 12.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Mem_trans PF03547.13 CDI74304.1 - 6.2 5.0 12.2 7.3 4.7 8.5 1.2 1 0 0 1 1 1 0 Membrane transport protein DUF1675 PF07897.6 CDI74304.1 - 6.3 6.5 15.8 7 6.4 11.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) Zip PF02535.17 CDI74304.1 - 6.4 5.6 15.9 6.9 5.5 11.0 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter PLRV_ORF5 PF01690.12 CDI74304.1 - 6.5 5.7 25.3 7.6 5.5 17.6 1.0 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein DUF913 PF06025.7 CDI74304.1 - 6.5 5.4 12.7 7.1 5.2 8.8 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) SAGA-Tad1 PF12767.2 CDI74304.1 - 7.2 6.1 28.0 11 5.6 19.4 1.3 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit CDK5_activator PF03261.10 CDI74304.1 - 7.8 5.7 23.7 9.5 5.4 16.4 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein TFIIA PF03153.8 CDI74304.1 - 7.9 6.2 48.3 9.5 6.0 33.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Neur_chan_memb PF02932.11 CDI74304.1 - 8.9 6.1 20.9 10 5.9 14.5 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Gag_spuma PF03276.9 CDI74304.1 - 9.1 4.4 42.3 10 4.2 29.3 1.1 1 0 0 1 1 1 0 Spumavirus gag protein Dicty_REP PF05086.7 CDI74304.1 - 9.6 3.8 17.4 9.7 3.8 12.0 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein SMC_N PF02463.14 CDI74305.1 - 1.2e-24 86.7 0.2 1.2e-24 86.7 0.1 2.4 2 2 0 2 2 2 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 CDI74305.1 - 1.6e-17 63.5 0.3 1.2e-16 60.7 0.0 2.7 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.1 CDI74305.1 - 3.4e-06 27.5 34.2 3.4e-06 27.5 23.7 6.3 2 2 0 2 2 2 1 AAA domain AAA_21 PF13304.1 CDI74305.1 - 2.4e-05 24.4 0.0 5.1e-05 23.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.1 CDI74305.1 - 0.0015 17.9 0.2 0.0052 16.2 0.0 1.9 2 0 0 2 2 2 1 P-loop containing region of AAA domain ADIP PF11559.3 CDI74305.1 - 0.0048 16.7 17.9 0.0048 16.7 12.4 7.3 5 2 2 7 7 7 1 Afadin- and alpha -actinin-Binding Reo_sigmaC PF04582.7 CDI74305.1 - 0.1 11.7 31.0 0.46 9.6 1.1 4.9 2 2 3 5 5 5 0 Reovirus sigma C capsid protein HlyD PF00529.15 CDI74306.1 - 0.38 10.0 4.3 0.39 9.9 3.0 1.0 1 0 0 1 1 1 0 HlyD family secretion protein DUF4602 PF15375.1 CDI74307.1 - 3.9e-06 26.9 4.1 3.9e-06 26.9 2.8 4.4 4 1 1 5 5 5 1 Domain of unknown function (DUF4602) TALPID3 PF15324.1 CDI74308.1 - 0.41 7.9 10.9 0.79 6.9 7.5 1.3 1 0 0 1 1 1 0 Hedgehog signalling target C2 PF00168.25 CDI74310.1 - 1.8e-13 50.0 0.0 7.2e-13 48.1 0.0 2.0 2 0 0 2 2 2 1 C2 domain SF3b1 PF08920.5 CDI74311.1 - 8.5e-21 74.5 0.0 1.7e-20 73.5 0.0 1.5 1 0 0 1 1 1 1 Splicing factor 3B subunit 1 HEAT_2 PF13646.1 CDI74311.1 - 5.5e-13 49.0 5.3 0.0064 16.7 0.0 7.1 5 2 3 8 8 8 5 HEAT repeats HEAT_EZ PF13513.1 CDI74311.1 - 1.2e-07 32.0 5.3 0.14 12.6 0.0 7.2 7 2 3 10 10 10 2 HEAT-like repeat HEAT PF02985.17 CDI74311.1 - 3.5e-07 29.7 14.1 1.1 9.5 0.1 8.8 9 0 0 9 9 9 2 HEAT repeat Adaptin_N PF01602.15 CDI74311.1 - 6.2e-06 24.8 2.8 0.054 11.8 0.0 4.0 4 1 1 5 5 5 3 Adaptin N terminal region UME PF08064.8 CDI74311.1 - 0.00017 21.5 0.3 0.43 10.5 0.0 4.2 4 0 0 4 4 4 1 UME (NUC010) domain Arm PF00514.18 CDI74311.1 - 0.0004 20.0 5.1 4.7 7.1 0.0 5.4 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat DUF2435 PF10363.4 CDI74311.1 - 0.0094 15.8 3.2 3.1 7.7 0.1 4.5 5 0 0 5 5 5 1 Protein of unknown function (DUF2435) CLASP_N PF12348.3 CDI74311.1 - 0.021 14.1 0.0 1 8.7 0.0 2.7 2 0 0 2 2 2 0 CLASP N terminal Cnd3 PF12719.2 CDI74311.1 - 0.043 12.8 1.1 0.54 9.1 0.0 2.9 3 0 0 3 3 3 0 Nuclear condensing complex subunits, C-term domain Spt20 PF12090.3 CDI74312.1 - 0.34 10.2 7.6 0.21 10.8 1.6 2.2 2 0 0 2 2 2 0 Spt20 family FimP PF09766.4 CDI74312.1 - 4.1 6.3 19.8 0.58 9.1 5.7 2.3 2 0 0 2 2 2 0 Fms-interacting protein P30 PF07390.6 CDI74313.1 - 1.3 8.4 5.4 1.9 7.9 3.7 1.2 1 0 0 1 1 1 0 Mycoplasma P30 protein EF-hand_7 PF13499.1 CDI74314.1 - 4.1e-30 103.7 6.2 1.4e-14 53.9 1.0 2.7 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.27 CDI74314.1 - 8.3e-30 99.8 3.9 1.5e-07 30.2 0.2 4.2 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.1 CDI74314.1 - 1.7e-26 91.5 6.8 4.6e-12 45.3 0.1 4.1 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.1 CDI74314.1 - 3.5e-24 82.4 5.7 2.9e-07 29.8 0.0 4.6 4 1 1 5 5 5 4 EF-hand domain EF-hand_5 PF13202.1 CDI74314.1 - 7.5e-17 59.8 12.2 3.2e-05 23.0 0.4 4.9 4 1 1 5 5 5 4 EF hand EF-hand_9 PF14658.1 CDI74314.1 - 1.7e-14 53.4 0.0 1e-07 31.7 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.2 CDI74314.1 - 2.6e-05 23.8 0.4 0.0098 15.6 0.1 2.7 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand TerB PF05099.8 CDI74314.1 - 0.0031 17.2 0.1 0.98 9.1 0.0 2.9 2 1 1 3 3 3 1 Tellurite resistance protein TerB Caleosin PF05042.8 CDI74314.1 - 0.011 15.2 0.0 0.32 10.5 0.0 2.5 2 1 1 3 3 3 0 Caleosin related protein DUF3008 PF11450.3 CDI74314.1 - 0.03 14.4 0.5 0.063 13.4 0.1 1.8 2 0 0 2 2 2 0 Protein of unknwon function (DUF3008) SPARC_Ca_bdg PF10591.4 CDI74314.1 - 0.032 14.2 0.0 3.8 7.5 0.0 2.2 1 1 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region UPF0154 PF03672.8 CDI74314.1 - 0.061 12.9 0.0 21 4.8 0.0 2.8 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0154) Acetyltransf_11 PF13720.1 CDI74314.1 - 0.1 12.8 0.0 1.6 8.9 0.0 2.3 1 1 0 2 2 2 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 LETM1 PF07766.8 CDI74314.1 - 0.11 11.4 0.1 5.2 6.0 0.1 2.2 1 1 1 2 2 2 0 LETM1-like protein Fe_dep_repress PF01325.14 CDI74314.1 - 0.15 12.0 0.1 0.6 10.0 0.0 2.1 2 0 0 2 2 2 0 Iron dependent repressor, N-terminal DNA binding domain Clathrin PF00637.15 CDI74315.1 - 2.8e-07 30.2 4.0 4.3e-06 26.3 0.3 3.4 2 1 0 2 2 2 1 Region in Clathrin and VPS Spore_coat_CotO PF14153.1 CDI74315.1 - 1.8e-05 24.2 23.6 1.8e-05 24.2 16.4 3.5 3 0 0 3 3 3 1 Spore coat protein CotO Caldesmon PF02029.10 CDI74315.1 - 8.6e-05 21.1 9.7 8.6e-05 21.1 6.7 2.9 4 0 0 4 4 4 1 Caldesmon SPX PF03105.14 CDI74315.1 - 0.00045 20.0 13.9 0.00045 20.0 9.6 2.4 2 1 0 2 2 1 1 SPX domain RR_TM4-6 PF06459.7 CDI74315.1 - 0.0023 17.8 14.1 0.0023 17.8 9.8 3.2 3 1 0 3 3 3 1 Ryanodine Receptor TM 4-6 Mem_trans PF03547.13 CDI74315.1 - 0.0035 15.6 4.7 0.0079 14.5 3.3 1.5 1 0 0 1 1 1 1 Membrane transport protein Neur_chan_memb PF02932.11 CDI74315.1 - 0.0062 16.4 12.9 0.0062 16.4 8.9 3.0 2 1 0 2 2 2 1 Neurotransmitter-gated ion-channel transmembrane region DUF2207 PF09972.4 CDI74315.1 - 0.073 11.6 6.8 0.041 12.4 2.5 2.0 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) SID-1_RNA_chan PF13965.1 CDI74315.1 - 0.12 10.5 10.6 0.26 9.4 7.3 1.7 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Drc1-Sld2 PF11719.3 CDI74315.1 - 0.98 8.4 30.9 0.055 12.5 17.7 1.6 2 0 0 2 2 2 0 DNA replication and checkpoint protein Serinc PF03348.10 CDI74315.1 - 1.1 7.9 31.4 0.0078 14.9 5.7 3.3 2 1 1 3 3 3 0 Serine incorporator (Serinc) PAT1 PF09770.4 CDI74315.1 - 1.8 6.6 105.6 0.015 13.5 52.6 2.1 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 DUF1675 PF07897.6 CDI74315.1 - 6.5 6.5 20.5 18 5.1 14.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) DUF3899 PF13038.1 CDI74315.1 - 8.9 6.5 17.8 0.17 12.0 0.2 4.5 3 1 1 4 4 3 0 Domain of unknown function (DUF3899) DUF1905 PF08922.6 CDI74316.1 - 0.025 14.1 0.0 0.039 13.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1905) BNIP2 PF12496.3 CDI74316.1 - 0.085 13.0 0.7 0.11 12.6 0.5 1.3 1 0 0 1 1 1 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 ADH_zinc_N PF00107.21 CDI74320.1 - 9.9e-24 83.3 0.1 1.4e-23 82.8 0.1 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 CDI74320.1 - 1.8e-15 56.5 2.8 1.8e-15 56.5 1.9 2.1 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain UDPG_MGDP_dh_N PF03721.9 CDI74320.1 - 0.0032 16.8 0.2 0.005 16.2 0.2 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 2-Hacid_dh_C PF02826.14 CDI74320.1 - 0.15 11.1 0.7 0.37 9.9 0.1 1.7 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain PuR_N PF09182.5 CDI74321.1 - 0.089 12.4 0.1 0.17 11.4 0.1 1.4 1 0 0 1 1 1 0 Bacterial purine repressor, N-terminal YSIRK_signal PF04650.12 CDI74321.1 - 3.7 7.1 8.0 3.2 7.3 2.5 2.4 2 0 0 2 2 2 0 YSIRK type signal peptide TRP PF06011.7 CDI74322.1 - 0.021 13.4 0.2 0.043 12.3 0.1 1.5 1 0 0 1 1 1 0 Transient receptor potential (TRP) ion channel Pkinase PF00069.20 CDI74324.1 - 3.7e-67 226.2 0.0 4.5e-67 225.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDI74324.1 - 2.4e-34 118.5 0.0 3e-34 118.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CDI74324.1 - 1.5e-06 27.4 0.0 7.5e-06 25.0 0.0 2.2 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.9 CDI74324.1 - 1.6e-05 24.0 0.0 2.7e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CDI74324.1 - 0.00022 21.0 0.0 0.41 10.3 0.0 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Cytokin-bind PF09265.5 CDI74324.1 - 0.01 14.9 0.0 0.036 13.1 0.0 1.7 2 0 0 2 2 2 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding YrbL-PhoP_reg PF10707.4 CDI74324.1 - 0.012 14.9 0.1 0.066 12.5 0.0 2.0 1 1 1 2 2 2 0 PhoP regulatory network protein YrbL RRM_1 PF00076.17 CDI74325.1 - 4.1e-18 64.7 0.1 6.4e-18 64.1 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CDI74325.1 - 7.9e-15 54.5 0.0 1.4e-14 53.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CDI74325.1 - 3.4e-07 29.9 0.0 6e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 CDI74325.1 - 0.0075 16.0 0.0 0.013 15.2 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif FlxA PF14282.1 CDI74327.1 - 0.0018 18.2 33.7 0.0018 18.2 23.3 10.9 9 2 1 10 10 10 1 FlxA-like protein SKG6 PF08693.5 CDI74327.1 - 0.11 11.8 0.0 0.53 9.6 0.0 2.3 1 0 0 1 1 1 0 Transmembrane alpha-helix domain PAT1 PF09770.4 CDI74328.1 - 0.083 11.1 56.4 0.096 10.9 39.1 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Pilt PF15453.1 CDI74328.1 - 0.09 12.4 26.7 0.13 11.9 18.5 1.2 1 0 0 1 1 1 0 Protein incorporated later into Tight Junctions FAM60A PF15396.1 CDI74328.1 - 0.82 9.3 12.9 1.1 8.9 9.0 1.4 1 0 0 1 1 1 0 Protein Family FAM60A GAGA_bind PF06217.7 CDI74328.1 - 1.5 8.7 20.9 1.9 8.3 14.5 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family Presenilin PF01080.12 CDI74328.1 - 4.3 6.0 14.3 5.7 5.6 9.9 1.3 1 0 0 1 1 1 0 Presenilin DUF2215 PF10225.4 CDI74328.1 - 8.8 5.6 9.2 12 5.2 6.4 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) Ashwin PF15323.1 CDI74330.1 - 1 9.2 13.9 1.2 9.0 9.6 1.1 1 0 0 1 1 1 0 Developmental protein MSP1_C PF07462.6 CDI74330.1 - 4.2 5.6 9.3 4.6 5.5 6.5 1.0 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus SRRM_C PF15230.1 CDI74330.1 - 4.9 7.3 19.4 0.065 13.3 4.6 2.5 2 1 0 2 2 2 0 Serine/arginine repetitive matrix protein C-terminus Phage_integrase PF00589.17 CDI74331.1 - 7.1e-18 64.8 0.0 1e-17 64.3 0.0 1.2 1 0 0 1 1 1 1 Phage integrase family zf-ribbon_3 PF13248.1 CDI74331.1 - 0.019 14.1 0.5 0.035 13.3 0.0 1.7 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_2 PF13240.1 CDI74331.1 - 0.098 12.1 0.8 0.14 11.6 0.0 1.7 2 0 0 2 2 2 0 zinc-ribbon domain DHC_N2 PF08393.8 CDI74335.1 - 5.3e-16 58.1 0.0 5.3e-16 58.1 0.0 2.3 3 1 0 3 3 3 1 Dynein heavy chain, N-terminal region 2 Baculo_PEP_C PF04513.7 CDI74335.1 - 0.0013 18.6 1.8 0.011 15.5 0.1 3.0 2 1 0 3 3 3 1 Baculovirus polyhedron envelope protein, PEP, C terminus FlaC_arch PF05377.6 CDI74335.1 - 0.0058 16.5 0.2 0.19 11.6 0.2 3.5 2 1 2 4 4 4 1 Flagella accessory protein C (FlaC) COG2 PF06148.6 CDI74335.1 - 0.01 15.7 1.4 0.37 10.6 0.5 3.1 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF4200 PF13863.1 CDI74335.1 - 0.013 15.4 4.1 0.079 12.9 0.9 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4200) Spc7 PF08317.6 CDI74335.1 - 0.059 12.0 1.4 0.12 11.0 0.6 1.6 1 1 0 1 1 1 0 Spc7 kinetochore protein DUF479 PF04336.7 CDI74335.1 - 0.067 13.2 0.4 10 6.2 0.0 3.0 2 2 1 3 3 3 0 Protein of unknown function, DUF479 DUF948 PF06103.6 CDI74335.1 - 0.15 11.9 1.5 1.3 8.8 0.1 3.1 2 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) HisKA_3 PF07730.8 CDI74335.1 - 0.19 12.1 1.3 1.7 9.0 0.0 3.1 3 1 1 4 4 4 0 Histidine kinase Reo_sigmaC PF04582.7 CDI74335.1 - 0.31 10.1 1.4 2 7.5 0.1 2.5 2 1 1 3 3 3 0 Reovirus sigma C capsid protein DivIC PF04977.10 CDI74335.1 - 0.45 10.0 2.3 5.2 6.6 1.0 2.9 3 0 0 3 3 3 0 Septum formation initiator NPV_P10 PF05531.7 CDI74335.1 - 1.1 9.5 6.7 0.44 10.8 0.4 3.2 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein TFIIA PF03153.8 CDI74336.1 - 0.74 9.6 50.1 1 9.1 34.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Lactonase PF10282.4 CDI74336.1 - 3.5 6.6 15.9 1.7 7.6 9.7 1.4 1 1 0 1 1 1 0 Lactonase, 7-bladed beta-propeller TraT PF05818.7 CDI74336.1 - 5.6 6.3 23.7 0.16 11.3 5.0 2.4 2 0 0 2 2 2 0 Enterobacterial TraT complement resistance protein PRA1 PF03208.14 CDI74337.1 - 0.001 18.4 0.0 0.033 13.5 0.0 2.1 2 0 0 2 2 2 1 PRA1 family protein Folate_carrier PF01770.13 CDI74337.1 - 0.0037 15.8 5.3 0.062 11.8 0.7 2.1 2 0 0 2 2 2 2 Reduced folate carrier TMEM154 PF15102.1 CDI74337.1 - 0.0039 16.9 7.8 0.2 11.3 0.2 2.1 2 0 0 2 2 2 2 TMEM154 protein family DUF4149 PF13664.1 CDI74337.1 - 0.028 14.4 2.4 0.048 13.7 0.3 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4149) DcuC PF03606.10 CDI74337.1 - 0.03 12.5 0.7 3.4 5.7 0.1 2.2 2 0 0 2 2 2 0 C4-dicarboxylate anaerobic carrier Succ_CoA_lig PF13607.1 CDI74337.1 - 0.05 13.2 4.1 0.8 9.3 0.0 2.3 2 0 0 2 2 2 0 Succinyl-CoA ligase like flavodoxin domain VanZ PF04892.7 CDI74337.1 - 0.051 13.5 0.5 0.13 12.2 0.2 1.8 1 1 0 1 1 1 0 VanZ like family FAM176 PF14851.1 CDI74337.1 - 0.073 12.7 0.3 0.073 12.7 0.2 1.8 2 1 1 3 3 3 0 FAM176 family MFS_Mycoplasma PF07672.8 CDI74337.1 - 0.091 11.9 3.2 1 8.4 0.0 2.1 1 1 1 2 2 2 0 Mycoplasma MFS transporter CDK2AP PF09806.4 CDI74337.1 - 0.091 12.9 11.0 0.042 14.0 0.5 2.1 2 0 0 2 2 2 0 Cyclin-dependent kinase 2-associated protein CemA PF03040.9 CDI74337.1 - 0.096 12.2 6.7 0.79 9.2 0.0 2.1 1 1 1 2 2 2 0 CemA family DUF2215 PF10225.4 CDI74337.1 - 0.12 11.7 1.1 0.22 10.9 0.8 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) DUF4179 PF13786.1 CDI74337.1 - 0.13 12.4 2.4 7.4 6.8 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4179) DUF788 PF05620.6 CDI74337.1 - 0.14 11.9 1.4 0.22 11.3 0.4 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF788) DUF3357 PF11837.3 CDI74337.1 - 0.28 11.0 3.2 1.1 9.1 0.1 2.5 1 1 2 3 3 3 0 Domain of unknown function (DUF3357) Med3 PF11593.3 CDI74337.1 - 0.71 9.0 17.5 1.2 8.2 0.5 2.2 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal DUF2232 PF09991.4 CDI74337.1 - 1.2 8.0 5.4 0.35 9.8 1.3 1.7 2 0 0 2 2 2 0 Predicted membrane protein (DUF2232) CHD5 PF04420.9 CDI74337.1 - 1.5 8.4 7.0 12 5.5 2.4 2.2 2 0 0 2 2 2 0 CHD5-like protein COX16 PF14138.1 CDI74337.1 - 1.7 8.9 9.9 2.8 8.1 3.0 2.5 3 0 0 3 3 2 0 Cytochrome c oxidase assembly protein COX16 RED_N PF07808.8 CDI74337.1 - 1.9 7.6 13.1 2 7.5 7.8 1.9 2 0 0 2 2 2 0 RED-like protein N-terminal region TMEM51 PF15345.1 CDI74337.1 - 2.3 7.8 8.5 9.3 5.8 3.5 2.2 2 1 0 2 2 2 0 Transmembrane protein 51 DUF1682 PF07946.9 CDI74337.1 - 2.3 6.9 13.5 4.1 6.1 9.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) RAB3GAP2_N PF14655.1 CDI74337.1 - 8.1 5.3 13.4 2.2 7.2 5.7 2.2 1 1 2 3 3 3 0 Rab3 GTPase-activating protein regulatory subunit N-terminus OAD_gamma PF04277.8 CDI74337.1 - 9 6.7 16.6 0.1 12.9 1.0 3.2 2 1 1 3 3 3 0 Oxaloacetate decarboxylase, gamma chain Shadoo PF14999.1 CDI74339.1 - 1.5 8.6 9.2 6.8 6.5 1.9 2.4 2 0 0 2 2 2 0 Shadow of prion protein, neuroprotective OPT PF03169.10 CDI74339.1 - 3.9 5.7 5.7 3.2 6.0 0.1 2.3 2 0 0 2 2 2 0 OPT oligopeptide transporter protein Ni_hydr_CYTB PF01292.15 CDI74339.1 - 4 6.7 7.8 2.5 7.4 0.2 3.1 2 1 1 3 3 3 0 Prokaryotic cytochrome b561 RAP1 PF07218.6 CDI74340.1 - 0.016 13.3 23.2 0.021 12.9 16.1 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) BSP_II PF05432.6 CDI74340.1 - 1.2 8.3 13.7 1.6 7.9 9.5 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) DUF2217 PF10265.4 CDI74340.1 - 1.4 7.5 34.6 1.6 7.3 24.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) CDC27 PF09507.5 CDI74340.1 - 3.6 6.7 49.4 4.8 6.2 34.2 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 DUF605 PF04652.11 CDI74340.1 - 4.1 6.7 57.3 4.9 6.4 39.7 1.0 1 0 0 1 1 1 0 Vta1 like Pox_E2-like PF04497.7 CDI74340.1 - 4.1 5.3 6.3 4.7 5.1 4.4 1.1 1 0 0 1 1 1 0 Poxviridae protein TFIIA PF03153.8 CDI74340.1 - 5.3 6.8 66.0 6.6 6.5 45.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit ARGLU PF15346.1 CDI74340.1 - 8.4 6.1 41.1 7.3 6.3 2.1 2.2 2 0 0 2 2 2 0 Arginine and glutamate-rich 1 Peptidase_S49_N PF08496.5 CDI74342.1 - 0.00071 19.3 5.8 0.00072 19.3 4.0 1.1 1 0 0 1 1 1 1 Peptidase family S49 N-terminal TraT PF05818.7 CDI74342.1 - 0.0011 18.4 4.3 0.0014 18.0 3.0 1.1 1 0 0 1 1 1 1 Enterobacterial TraT complement resistance protein FimP PF09766.4 CDI74342.1 - 0.0018 17.4 12.3 0.0018 17.4 8.5 1.0 1 0 0 1 1 1 1 Fms-interacting protein TPP_enzyme_C PF02775.16 CDI74342.1 - 0.0046 16.5 0.2 0.0057 16.2 0.1 1.1 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Serinc PF03348.10 CDI74342.1 - 0.016 13.9 4.3 0.018 13.8 3.0 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) MRP-S31 PF15433.1 CDI74342.1 - 0.025 14.0 11.1 0.037 13.4 7.7 1.2 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 DUF3169 PF11368.3 CDI74342.1 - 0.03 13.5 0.2 0.035 13.3 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3169) PEX11 PF05648.9 CDI74342.1 - 0.035 13.3 4.3 0.038 13.2 3.0 1.2 1 0 0 1 1 1 0 Peroxisomal biogenesis factor 11 (PEX11) KBP_C PF12309.3 CDI74342.1 - 0.037 13.0 10.6 0.038 12.9 7.4 1.0 1 0 0 1 1 1 0 KIF-1 binding protein C terminal SDF PF00375.13 CDI74342.1 - 0.039 12.7 0.2 0.055 12.2 0.2 1.4 1 1 0 1 1 1 0 Sodium:dicarboxylate symporter family OATP PF03137.15 CDI74342.1 - 0.044 11.8 2.8 0.041 11.9 2.0 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family DnaJ-X PF14308.1 CDI74342.1 - 0.052 12.8 9.1 0.06 12.6 6.3 1.1 1 0 0 1 1 1 0 X-domain of DnaJ-containing FAM176 PF14851.1 CDI74342.1 - 0.053 13.1 0.9 0.06 13.0 0.6 1.2 1 0 0 1 1 1 0 FAM176 family DDHD PF02862.12 CDI74342.1 - 0.055 13.2 5.0 0.056 13.2 3.5 1.1 1 0 0 1 1 1 0 DDHD domain RskA PF10099.4 CDI74342.1 - 0.061 13.0 11.4 0.1 12.3 7.9 1.3 1 0 0 1 1 1 0 Anti-sigma-K factor rskA TMEM51 PF15345.1 CDI74342.1 - 0.068 12.8 6.1 0.065 12.9 4.2 1.1 1 0 0 1 1 1 0 Transmembrane protein 51 DcuC PF03606.10 CDI74342.1 - 0.079 11.1 1.9 0.097 10.8 1.3 1.0 1 0 0 1 1 1 0 C4-dicarboxylate anaerobic carrier eIF-3_zeta PF05091.7 CDI74342.1 - 0.12 10.9 9.5 0.12 10.9 6.6 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Suf PF05843.9 CDI74342.1 - 0.13 11.9 12.0 0.13 12.0 8.3 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF2828 PF11443.3 CDI74342.1 - 0.13 10.4 5.9 0.13 10.3 4.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) DUF897 PF05982.7 CDI74342.1 - 0.14 10.9 2.8 0.18 10.5 2.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF897) 7tm_7 PF08395.7 CDI74342.1 - 0.14 11.1 6.1 0.15 11.0 4.2 1.1 1 0 0 1 1 1 0 7tm Chemosensory receptor Ufd2P_core PF10408.4 CDI74342.1 - 0.14 10.3 11.9 0.16 10.2 8.2 1.0 1 0 0 1 1 1 0 Ubiquitin elongating factor core DUF2235 PF09994.4 CDI74342.1 - 0.15 11.3 2.9 0.17 11.2 2.0 1.1 1 0 0 1 1 1 0 Uncharacterized alpha/beta hydrolase domain (DUF2235) Bap31 PF05529.7 CDI74342.1 - 0.16 11.4 11.7 0.21 11.0 8.1 1.2 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like Baculo_PP31 PF05311.6 CDI74342.1 - 0.17 11.1 8.5 0.19 10.9 5.9 1.1 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) Dala_Dala_lig_N PF01820.16 CDI74342.1 - 0.22 11.8 2.5 0.25 11.6 1.7 1.2 1 0 0 1 1 1 0 D-ala D-ala ligase N-terminus DUF4557 PF15101.1 CDI74342.1 - 0.23 11.2 17.2 0.24 11.1 11.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) PAT1 PF09770.4 CDI74342.1 - 0.24 9.5 22.7 0.24 9.6 15.7 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Peptidase_S15 PF02129.13 CDI74342.1 - 0.24 10.7 10.7 0.29 10.5 7.4 1.0 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) CemA PF03040.9 CDI74342.1 - 0.28 10.7 3.8 0.25 10.9 2.6 1.1 1 0 0 1 1 1 0 CemA family DUF2232 PF09991.4 CDI74342.1 - 0.32 9.9 6.6 0.42 9.5 4.6 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) DUF912 PF06024.7 CDI74342.1 - 0.47 10.5 5.4 0.81 9.7 3.8 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Neur_chan_memb PF02932.11 CDI74342.1 - 0.54 10.0 3.1 0.63 9.8 2.1 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF775 PF05603.7 CDI74342.1 - 0.68 9.4 9.4 0.76 9.2 6.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF775) DUF2215 PF10225.4 CDI74342.1 - 0.74 9.2 4.2 0.83 9.0 2.9 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) Peptidase_U57 PF05582.7 CDI74342.1 - 0.77 8.6 6.0 0.77 8.6 4.2 1.1 1 0 0 1 1 1 0 YabG peptidase U57 PBP_sp32 PF07222.7 CDI74342.1 - 0.85 8.7 12.3 0.87 8.7 8.5 1.1 1 0 0 1 1 1 0 Proacrosin binding protein sp32 GvpL_GvpF PF06386.6 CDI74342.1 - 0.89 9.0 11.6 0.92 9.0 8.0 1.2 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF Band_3_cyto PF07565.8 CDI74342.1 - 0.97 8.8 9.6 1.1 8.6 6.7 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain DUF342 PF03961.8 CDI74342.1 - 1 7.7 9.1 1.1 7.6 6.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF1764 PF08576.5 CDI74342.1 - 1.3 9.8 12.1 1.8 9.3 8.4 1.1 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) AIF_C PF14721.1 CDI74342.1 - 1.6 8.9 6.7 2.9 8.1 4.6 1.4 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Pex16 PF08610.5 CDI74342.1 - 1.7 7.5 10.8 2 7.3 7.5 1.1 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) Cyclin_C PF02984.14 CDI74342.1 - 2 8.3 7.8 3 7.7 5.4 1.4 1 0 0 1 1 1 0 Cyclin, C-terminal domain HemX PF04375.9 CDI74342.1 - 2.2 6.7 32.3 2.6 6.5 22.4 1.0 1 0 0 1 1 1 0 HemX DUF1800 PF08811.6 CDI74342.1 - 2.4 6.9 19.0 2.6 6.8 13.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1800) Nucleoside_tran PF01733.13 CDI74342.1 - 2.6 7.1 6.2 2.4 7.2 4.0 1.3 1 1 0 1 1 1 0 Nucleoside transporter Apc1 PF12859.2 CDI74342.1 - 3.2 8.0 8.3 4.2 7.6 5.8 1.2 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 1 RR_TM4-6 PF06459.7 CDI74342.1 - 3.6 7.3 10.5 4.4 7.1 7.3 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 EIIBC-GUT_N PF03612.9 CDI74342.1 - 4 7.0 9.8 5.6 6.5 6.8 1.2 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Glyco_transf_15 PF01793.11 CDI74342.1 - 4.2 6.2 9.1 4.8 6.0 6.3 1.1 1 0 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase CRF1 PF10380.4 CDI74342.1 - 4.7 7.5 6.2 5.6 7.3 4.3 1.1 1 0 0 1 1 1 0 Transcription factor CRF1 Anoctamin PF04547.7 CDI74342.1 - 5.2 5.5 12.0 7.3 5.1 8.3 1.2 1 0 0 1 1 1 0 Calcium-activated chloride channel SHR3_chaperone PF08229.6 CDI74342.1 - 6.9 5.5 12.8 9.4 5.1 8.9 1.2 1 0 0 1 1 1 0 ER membrane protein SH3 RED_N PF07808.8 CDI74342.1 - 8.9 5.4 20.0 11 5.1 13.9 1.1 1 0 0 1 1 1 0 RED-like protein N-terminal region Activator_LAG-3 PF11498.3 CDI74342.1 - 9.6 4.8 43.2 10 4.6 29.9 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Chromo PF00385.19 CDI74345.1 - 4.7e-10 38.9 0.0 7.8e-10 38.2 0.0 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain fn3 PF00041.16 CDI74345.1 - 0.0031 17.6 0.0 0.004 17.2 0.0 1.2 1 0 0 1 1 1 1 Fibronectin type III domain Peptidase_S49_N PF08496.5 CDI74348.1 - 0.00019 21.2 5.3 0.00027 20.7 3.7 1.3 1 0 0 1 1 1 1 Peptidase family S49 N-terminal DUF1510 PF07423.6 CDI74348.1 - 0.00035 20.0 7.3 0.00042 19.7 5.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) Med15 PF09606.5 CDI74348.1 - 0.0021 16.3 22.0 0.0022 16.2 15.3 1.1 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal DUF4446 PF14584.1 CDI74348.1 - 0.0031 17.3 4.2 0.0051 16.6 2.9 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4446) SID-1_RNA_chan PF13965.1 CDI74348.1 - 0.009 14.2 2.5 0.01 14.0 1.7 1.0 1 0 0 1 1 1 1 dsRNA-gated channel SID-1 RAB3GAP2_N PF14655.1 CDI74348.1 - 0.0093 15.0 6.4 0.011 14.7 4.5 1.1 1 0 0 1 1 1 1 Rab3 GTPase-activating protein regulatory subunit N-terminus Ycf1 PF05758.7 CDI74348.1 - 0.013 13.2 0.2 0.014 13.1 0.1 1.0 1 0 0 1 1 1 0 Ycf1 DUF106 PF01956.11 CDI74348.1 - 0.016 14.7 0.9 0.022 14.2 0.6 1.2 1 0 0 1 1 1 0 Integral membrane protein DUF106 Neur_chan_memb PF02932.11 CDI74348.1 - 0.025 14.4 3.8 0.03 14.2 2.6 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF3115 PF11312.3 CDI74348.1 - 0.03 13.1 3.5 0.034 13.0 2.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3115) DUF1980 PF09323.5 CDI74348.1 - 0.046 13.4 0.4 0.066 12.9 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) Spt20 PF12090.3 CDI74348.1 - 0.062 12.6 1.9 0.069 12.4 1.3 1.1 1 0 0 1 1 1 0 Spt20 family Serinc PF03348.10 CDI74348.1 - 0.13 10.8 4.9 0.16 10.6 3.4 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) FimP PF09766.4 CDI74348.1 - 0.17 10.9 6.6 0.2 10.6 4.6 1.1 1 0 0 1 1 1 0 Fms-interacting protein Sporozoite_P67 PF05642.6 CDI74348.1 - 0.19 9.5 13.4 0.21 9.3 9.3 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF4557 PF15101.1 CDI74348.1 - 0.21 11.4 7.6 0.23 11.2 5.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) Mcm10 PF09332.6 CDI74348.1 - 0.26 10.5 11.6 0.32 10.2 8.1 1.2 1 0 0 1 1 1 0 Mcm10 replication factor SIT PF15330.1 CDI74348.1 - 0.32 11.1 5.3 0.47 10.6 3.4 1.4 1 1 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT SP_C-Propep PF08999.5 CDI74348.1 - 0.57 9.7 6.6 1.2 8.6 4.6 1.6 1 0 0 1 1 1 0 Surfactant protein C, N terminal propeptide MCPVI PF02993.9 CDI74348.1 - 0.67 10.0 12.5 0.86 9.7 8.7 1.2 1 0 0 1 1 1 0 Minor capsid protein VI DDHD PF02862.12 CDI74348.1 - 0.72 9.6 4.5 0.83 9.3 3.1 1.1 1 0 0 1 1 1 0 DDHD domain Herpes_gE PF02480.11 CDI74348.1 - 0.82 7.8 9.6 0.024 12.9 1.5 1.8 1 1 1 2 2 2 0 Alphaherpesvirus glycoprotein E DUF2201_N PF13203.1 CDI74348.1 - 0.99 8.5 14.1 1.2 8.2 9.8 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain CDK5_activator PF03261.10 CDI74348.1 - 1.1 8.4 6.6 1.2 8.3 4.6 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein Shisa PF13908.1 CDI74348.1 - 1.3 9.1 21.0 4.2 7.5 14.5 1.8 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator GNT-I PF03071.10 CDI74348.1 - 2.3 6.6 6.0 2.8 6.3 4.1 1.1 1 0 0 1 1 1 0 GNT-I family Hid1 PF12722.2 CDI74348.1 - 2.3 5.7 6.5 2.5 5.6 4.5 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF2217 PF10265.4 CDI74348.1 - 3.2 6.4 7.7 3.8 6.1 5.3 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) Paramyxo_ncap PF00973.14 CDI74348.1 - 3.7 6.1 7.8 4.1 5.9 5.4 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Baculo_11_kDa PF06143.6 CDI74348.1 - 7.1 6.0 8.8 0.39 10.1 0.2 2.4 2 0 0 2 2 2 0 Baculovirus 11 kDa family DUF1675 PF07897.6 CDI74348.1 - 9.6 5.9 10.7 12 5.6 7.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) Med15 PF09606.5 CDI74349.1 - 2.6e-06 26.0 170.4 0.0015 16.8 56.2 3.2 3 0 0 3 3 3 3 ARC105 or Med15 subunit of Mediator complex non-fungal AAA PF00004.24 CDI74350.1 - 2.6e-52 176.5 0.1 3.1e-24 85.6 0.0 6.7 5 1 0 5 5 5 4 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 CDI74350.1 - 2.5e-09 36.9 1.7 0.0035 17.0 0.0 4.2 3 1 1 4 4 4 2 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 CDI74350.1 - 5.7e-08 33.6 0.0 0.0021 18.8 0.0 2.8 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.17 CDI74350.1 - 1.4e-07 31.5 0.1 0.035 14.2 0.0 3.1 2 0 0 2 2 2 2 RNA helicase AAA_14 PF13173.1 CDI74350.1 - 7.8e-07 29.0 0.3 0.023 14.6 0.0 4.0 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.1 CDI74350.1 - 1.4e-06 28.5 8.5 0.014 15.5 0.0 5.1 3 3 0 3 3 2 2 AAA domain AAA_16 PF13191.1 CDI74350.1 - 2.1e-06 27.8 3.9 0.00054 20.0 0.6 7.3 4 3 0 5 5 3 2 AAA ATPase domain IstB_IS21 PF01695.12 CDI74350.1 - 1e-05 25.0 0.0 0.0033 16.8 0.0 3.4 4 0 0 4 4 2 2 IstB-like ATP binding protein AAA_33 PF13671.1 CDI74350.1 - 6.2e-05 22.9 0.4 0.0047 16.8 0.1 7.4 6 2 0 6 6 4 2 AAA domain TIP49 PF06068.8 CDI74350.1 - 0.00018 20.3 5.4 0.076 11.7 0.0 2.8 3 0 0 3 3 2 2 TIP49 C-terminus RuvB_N PF05496.7 CDI74350.1 - 0.001 18.1 9.8 0.012 14.7 0.0 4.7 5 0 0 5 5 4 1 Holliday junction DNA helicase ruvB N-terminus DUF755 PF05501.6 CDI74350.1 - 0.002 18.1 17.6 0.002 18.1 12.2 13.0 8 4 2 10 10 3 2 Domain of unknown function (DUF755) AAA_18 PF13238.1 CDI74350.1 - 0.017 15.4 0.0 0.037 14.3 0.0 4.1 5 1 0 5 5 3 0 AAA domain P12 PF12669.2 CDI74350.1 - 0.54 10.5 7.7 0.24 11.6 1.7 3.3 2 0 0 2 2 2 0 Virus attachment protein p12 family Arch_ATPase PF01637.13 CDI74350.1 - 2.3 7.8 5.4 7.6 6.1 0.0 3.3 4 0 0 4 4 4 0 Archaeal ATPase N6_N4_Mtase PF01555.13 CDI74353.1 - 0.054 12.9 0.0 0.054 12.9 0.0 4.3 3 2 0 3 3 3 0 DNA methylase EF-hand_1 PF00036.27 CDI74354.1 - 9.3e-07 27.7 1.3 1.5e-05 23.9 0.1 2.7 3 0 0 3 3 3 1 EF hand EF-hand_6 PF13405.1 CDI74354.1 - 3.5e-06 26.4 1.0 0.00016 21.2 0.1 2.6 1 1 1 2 2 2 1 EF-hand domain EF-hand_5 PF13202.1 CDI74354.1 - 4.6e-06 25.7 1.0 2e-05 23.7 0.1 2.2 3 0 0 3 3 3 1 EF hand EF-hand_7 PF13499.1 CDI74354.1 - 1.1e-05 25.4 0.2 2.3e-05 24.4 0.1 1.7 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.1 CDI74354.1 - 0.006 16.1 0.7 0.12 12.0 0.1 2.3 1 1 1 2 2 2 1 EF-hand domain pair E1-E2_ATPase PF00122.15 CDI74355.1 - 8.9e-06 24.9 0.2 0.00044 19.3 0.0 2.7 3 0 0 3 3 3 1 E1-E2 ATPase Pex14_N PF04695.8 CDI74355.1 - 0.0025 17.8 4.9 0.0025 17.8 3.4 3.2 3 1 0 3 3 3 1 Peroxisomal membrane anchor protein (Pex14p) conserved region DivIC PF04977.10 CDI74355.1 - 0.011 15.2 7.4 0.027 13.9 5.1 1.6 1 0 0 1 1 1 0 Septum formation initiator RAB3GAP2_N PF14655.1 CDI74355.1 - 0.061 12.3 1.4 0.097 11.6 1.0 1.2 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Suf PF05843.9 CDI74355.1 - 0.098 12.3 2.8 0.2 11.3 1.9 1.4 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) VID27 PF08553.5 CDI74355.1 - 0.17 10.0 0.2 0.26 9.4 0.1 1.1 1 0 0 1 1 1 0 VID27 cytoplasmic protein Hydrolase PF00702.21 CDI74357.1 - 2.2e-08 34.7 4.7 2.4e-06 28.1 0.5 3.4 3 1 0 3 3 3 2 haloacid dehalogenase-like hydrolase HAD PF12710.2 CDI74357.1 - 5.6e-06 26.6 0.0 1.5e-05 25.2 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase PIN_4 PF13638.1 CDI74357.1 - 0.077 13.0 0.3 0.077 13.0 0.2 2.5 2 0 0 2 2 2 0 PIN domain TFIIA PF03153.8 CDI74357.1 - 0.78 9.5 55.3 1.3 8.8 18.3 3.2 3 0 0 3 3 3 0 Transcription factor IIA, alpha/beta subunit OmpH PF03938.9 CDI74357.1 - 1.5 8.7 79.4 1.6 8.6 22.2 3.5 3 0 0 3 3 3 0 Outer membrane protein (OmpH-like) Hydrolase_3 PF08282.7 CDI74357.1 - 9.1 5.7 11.9 0.32 10.5 3.2 2.2 2 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase ApbA PF02558.11 CDI74358.1 - 0.0022 17.4 0.0 0.0061 16.0 0.0 1.7 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA HATPase_c PF02518.21 CDI74360.1 - 6.1e-05 22.6 0.0 0.00025 20.7 0.0 2.0 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SprA-related PF12118.3 CDI74360.1 - 0.0006 19.2 34.6 0.0006 19.2 24.0 7.5 3 1 0 4 4 4 1 SprA-related family DUF605 PF04652.11 CDI74360.1 - 0.00063 19.2 21.3 0.00063 19.2 14.7 4.9 2 1 1 4 4 4 1 Vta1 like Med15 PF09606.5 CDI74360.1 - 0.0018 16.6 30.1 0.0018 16.6 20.9 5.4 5 1 0 5 5 5 2 ARC105 or Med15 subunit of Mediator complex non-fungal DUF3112 PF11309.3 CDI74360.1 - 0.12 12.2 0.9 1.3 8.8 0.0 3.2 3 1 0 3 3 3 0 Protein of unknown function (DUF3112) IncA PF04156.9 CDI74361.1 - 9e-05 22.1 16.2 9e-05 22.1 11.2 3.8 2 2 1 3 3 3 1 IncA protein ABC_tran PF00005.22 CDI74362.1 - 9.1e-31 106.9 9.1 1.3e-28 100.0 4.1 2.9 2 1 0 2 2 1 1 ABC transporter ABC_membrane PF00664.18 CDI74362.1 - 3.4e-11 43.0 0.3 5.6e-11 42.3 0.2 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.14 CDI74362.1 - 2.9e-09 36.5 0.9 3.6e-07 29.6 1.1 2.3 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_25 PF13481.1 CDI74362.1 - 3.4e-05 23.3 0.0 0.038 13.4 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_21 PF13304.1 CDI74362.1 - 4.5e-05 23.5 0.0 0.04 13.8 0.0 2.2 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 CDI74362.1 - 9.3e-05 22.5 3.1 0.085 13.0 0.0 3.3 2 1 1 3 3 3 2 AAA domain AAA_17 PF13207.1 CDI74362.1 - 0.00026 21.8 0.0 0.00066 20.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.1 CDI74362.1 - 0.0012 18.2 0.0 0.0031 17.0 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain Med15 PF09606.5 CDI74362.1 - 0.0025 16.0 49.0 0.0025 16.0 34.0 2.5 3 0 0 3 3 2 2 ARC105 or Med15 subunit of Mediator complex non-fungal AAA PF00004.24 CDI74362.1 - 0.0026 17.9 1.3 2 8.6 0.5 3.0 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 CDI74362.1 - 0.012 15.4 0.0 0.17 11.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.9 CDI74362.1 - 0.015 15.0 0.0 0.044 13.5 0.0 1.8 2 0 0 2 2 1 0 AAA domain (dynein-related subfamily) AAA_10 PF12846.2 CDI74362.1 - 0.016 14.6 0.0 2.2 7.6 0.0 2.4 2 0 0 2 2 2 0 AAA-like domain AAA_23 PF13476.1 CDI74362.1 - 0.024 14.9 25.8 3 8.1 0.0 3.0 3 0 0 3 3 3 0 AAA domain SbcCD_C PF13558.1 CDI74362.1 - 0.065 13.1 3.8 0.12 12.2 0.3 3.3 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit DUF4045 PF13254.1 CDI74362.1 - 0.069 12.4 20.8 0.06 12.6 7.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4045) G-alpha PF00503.15 CDI74362.1 - 0.18 10.4 0.0 0.18 10.4 0.0 2.6 2 1 1 3 3 2 0 G-protein alpha subunit Spore_coat_CotO PF14153.1 CDI74362.1 - 0.31 10.4 28.3 0.071 12.5 14.4 2.2 2 0 0 2 2 2 0 Spore coat protein CotO FLO_LFY PF01698.11 CDI74362.1 - 0.36 9.6 16.0 0.061 12.1 6.9 2.1 2 0 0 2 2 2 0 Floricaula / Leafy protein SAPS PF04499.10 CDI74362.1 - 0.55 8.7 13.1 1.1 7.7 9.2 1.4 1 1 0 1 1 1 0 SIT4 phosphatase-associated protein LMBR1 PF04791.11 CDI74362.1 - 0.62 8.5 1.4 0.9 8.0 1.0 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein DDHD PF02862.12 CDI74362.1 - 0.81 9.4 19.2 0.31 10.8 9.8 2.1 2 0 0 2 2 2 0 DDHD domain GAGA_bind PF06217.7 CDI74362.1 - 1.2 8.9 20.9 2.8 7.8 10.1 2.1 2 0 0 2 2 2 0 GAGA binding protein-like family Band_3_cyto PF07565.8 CDI74362.1 - 2.1 7.7 20.6 0.92 8.9 10.4 2.2 2 0 0 2 2 2 0 Band 3 cytoplasmic domain Dala_Dala_lig_N PF01820.16 CDI74362.1 - 2.2 8.6 9.3 21 5.4 5.0 3.1 3 0 0 3 3 3 0 D-ala D-ala ligase N-terminus Hid1 PF12722.2 CDI74362.1 - 4 4.9 20.3 0.32 8.6 10.3 1.7 2 0 0 2 2 2 0 High-temperature-induced dauer-formation protein DUF702 PF05142.7 CDI74362.1 - 4.1 7.5 28.1 0.09 12.9 10.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF702) DUF1311 PF07007.7 CDI74364.1 - 0.15 12.1 3.0 0.21 11.7 2.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1311) DUF106 PF01956.11 CDI74364.1 - 0.19 11.2 1.1 0.21 11.1 0.7 1.1 1 0 0 1 1 1 0 Integral membrane protein DUF106 TcdB_N PF12918.2 CDI74364.1 - 0.2 11.7 1.0 8.9 6.4 0.4 2.4 1 1 1 2 2 2 0 TcdB toxin N-terminal helical domain YlqD PF11068.3 CDI74364.1 - 0.45 10.5 7.6 0.59 10.1 5.3 1.1 1 0 0 1 1 1 0 YlqD protein Tho2 PF11262.3 CDI74364.1 - 1.7 7.6 6.7 3 6.7 1.2 2.1 1 1 1 2 2 2 0 Transcription factor/nuclear export subunit protein 2 GIY-YIG PF01541.19 CDI74364.1 - 5.7 7.3 9.8 19 5.7 6.8 1.9 1 1 0 1 1 1 0 GIY-YIG catalytic domain DUF3801 PF12687.2 CDI74373.1 - 8.6e-06 25.4 0.2 9.3e-06 25.3 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3801) PAT1 PF09770.4 CDI74373.1 - 0.0085 14.3 42.3 0.01 14.1 29.3 1.2 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 SR-25 PF10500.4 CDI74373.1 - 0.43 10.0 35.5 1.1 8.7 24.6 1.6 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein Med15 PF09606.5 CDI74373.1 - 1.8 6.6 75.6 0.06 11.5 42.2 2.3 2 1 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal FAM60A PF15396.1 CDI74373.1 - 4.1 7.0 19.3 5.8 6.5 13.4 1.2 1 0 0 1 1 1 0 Protein Family FAM60A CDC45 PF02724.9 CDI74373.1 - 7.8 4.4 19.2 9.9 4.0 13.3 1.1 1 0 0 1 1 1 0 CDC45-like protein CDC45 PF02724.9 CDI74374.1 - 0.55 8.2 37.7 0.71 7.8 26.1 1.2 1 0 0 1 1 1 0 CDC45-like protein RAB3GAP2_N PF14655.1 CDI74375.1 - 0.0024 16.9 0.3 0.0024 16.9 0.2 4.2 3 2 1 4 4 4 1 Rab3 GTPase-activating protein regulatory subunit N-terminus BAF1_ABF1 PF04684.8 CDI74376.1 - 1.1e-05 24.4 17.1 1.1e-05 24.4 11.8 4.0 3 1 0 3 3 3 1 BAF1 / ABF1 chromatin reorganising factor WD40 PF00400.27 CDI74376.1 - 0.00061 19.5 0.0 0.00061 19.5 0.0 3.3 3 1 0 3 3 3 1 WD domain, G-beta repeat Gly-zipper_OmpA PF13436.1 CDI74376.1 - 0.00074 19.1 10.7 0.00074 19.1 7.4 4.8 3 1 2 5 5 5 1 Glycine-zipper containing OmpA-like membrane domain CAF-1_p150 PF11600.3 CDI74376.1 - 0.0018 17.7 10.7 0.0018 17.7 7.4 5.7 5 1 0 6 6 6 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal SGT1 PF07093.6 CDI74376.1 - 1.7 6.9 27.9 0.93 7.7 8.4 2.2 2 0 0 2 2 2 0 SGT1 protein DBC1 PF14443.1 CDI74376.1 - 6.1 6.3 9.1 13 5.3 0.5 2.5 2 0 0 2 2 2 0 DBC1 Ycf1 PF05758.7 CDI74377.1 - 0.0036 15.0 10.9 0.0037 15.0 7.6 1.1 1 0 0 1 1 1 1 Ycf1 APC_CDC26 PF10471.4 CDI74377.1 - 0.08 13.6 1.4 0.08 13.6 0.9 4.6 2 1 0 2 2 1 0 Anaphase-promoting complex APC subunit 1 Caldesmon PF02029.10 CDI74377.1 - 0.16 10.3 19.3 0.21 9.9 13.4 1.2 1 0 0 1 1 1 0 Caldesmon DUF2126 PF09899.4 CDI74377.1 - 0.17 9.8 9.6 0.21 9.6 6.7 1.2 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) Utp14 PF04615.8 CDI74377.1 - 0.18 9.9 28.3 0.24 9.5 19.6 1.1 1 0 0 1 1 1 0 Utp14 protein Hid1 PF12722.2 CDI74377.1 - 0.19 9.3 25.5 0.28 8.8 17.7 1.3 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Peptidase_S49_N PF08496.5 CDI74377.1 - 0.23 11.2 13.1 0.57 9.9 9.1 1.8 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Pox_A21 PF05323.7 CDI74377.1 - 0.25 11.7 0.9 0.55 10.6 0.2 1.9 1 1 1 2 2 2 0 Poxvirus A21 Protein Asp-B-Hydro_N PF05279.6 CDI74377.1 - 0.55 10.0 12.7 0.72 9.6 8.8 1.3 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region RR_TM4-6 PF06459.7 CDI74377.1 - 0.94 9.3 22.9 0.079 12.8 12.4 1.8 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 BTV_NS2 PF04514.7 CDI74377.1 - 1 8.1 13.3 1.6 7.5 9.2 1.2 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 DDRGK PF09756.4 CDI74377.1 - 2.6 7.4 26.6 4.3 6.6 18.4 1.3 1 0 0 1 1 1 0 DDRGK domain eIF-3_zeta PF05091.7 CDI74377.1 - 2.8 6.4 23.8 4 5.9 16.5 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Peptidase_U57 PF05582.7 CDI74377.1 - 3.2 6.6 11.2 5.8 5.8 7.7 1.5 1 0 0 1 1 1 0 YabG peptidase U57 Nucleoside_tran PF01733.13 CDI74377.1 - 6.5 5.8 7.8 1.9 7.5 3.3 1.7 2 0 0 2 2 2 0 Nucleoside transporter SID-1_RNA_chan PF13965.1 CDI74377.1 - 7.6 4.5 10.4 10 4.1 7.2 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Dicty_REP PF05086.7 CDI74377.1 - 7.9 4.0 16.7 11 3.5 11.6 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Otopetrin PF03189.8 CDI74377.1 - 8.6 5.2 10.1 13 4.5 7.0 1.5 1 0 0 1 1 1 0 Otopetrin Atrophin-1 PF03154.10 CDI74378.1 - 0.025 12.7 9.1 0.034 12.3 6.3 1.2 1 0 0 1 1 1 0 Atrophin-1 family WD40 PF00400.27 CDI74379.1 - 1.4e-36 123.0 6.7 4.4e-08 32.6 0.0 6.2 6 0 0 6 6 6 6 WD domain, G-beta repeat MIP-T3 PF10243.4 CDI74380.1 - 0.31 9.4 20.7 0.31 9.4 14.4 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Trypan_PARP PF05887.6 CDI74380.1 - 0.32 10.8 18.0 0.38 10.5 12.5 1.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DDHD PF02862.12 CDI74380.1 - 2.1 8.0 8.9 2.3 7.9 6.2 1.1 1 0 0 1 1 1 0 DDHD domain FLO_LFY PF01698.11 CDI74380.1 - 4.5 6.0 11.1 4.5 6.0 7.7 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein UPF0560 PF10577.4 CDI74380.1 - 6.2 4.9 8.9 6.7 4.8 6.2 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 U1snRNP70_N PF12220.3 CDI74380.1 - 9.9 6.5 10.6 14 6.0 7.3 1.3 1 0 0 1 1 1 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal ERK-JNK_inhib PF15002.1 CDI74381.1 - 1.1 8.5 8.0 16 4.7 3.4 2.2 2 0 0 2 2 2 0 ERK and JNK pathways, inhibitor CitT PF12431.3 CDI74383.1 - 0.13 12.3 0.0 0.32 11.0 0.0 1.7 1 0 0 1 1 1 0 Transcriptional regulator MORN PF02493.15 CDI74384.1 - 1.5e-51 169.1 51.6 6e-07 28.8 1.3 10.2 10 0 0 10 10 10 10 MORN repeat Ras PF00071.17 CDI74385.1 - 9.4e-57 190.9 0.0 1.2e-56 190.6 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CDI74385.1 - 1.6e-17 64.1 0.0 2.4e-17 63.5 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CDI74385.1 - 1.2e-13 50.6 0.0 1.6e-13 50.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 CDI74385.1 - 9.3e-08 31.4 0.0 1.1e-07 31.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 CDI74385.1 - 0.00018 21.0 0.0 0.00062 19.2 0.0 1.7 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 CDI74385.1 - 0.00084 19.2 0.0 0.0014 18.5 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.12 CDI74385.1 - 0.019 14.5 0.0 0.036 13.5 0.0 1.4 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein DUF2280 PF10045.4 CDI74385.1 - 0.11 12.4 0.1 0.17 11.8 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2280) Pkinase PF00069.20 CDI74386.1 - 1.1e-37 129.5 1.3 1.2e-26 93.3 0.0 4.9 4 2 0 4 4 4 2 Protein kinase domain Pkinase_Tyr PF07714.12 CDI74386.1 - 1.1e-36 126.3 0.0 3.9e-14 52.3 0.0 4.8 3 2 1 4 4 4 3 Protein tyrosine kinase AAA PF00004.24 CDI74387.1 - 5e-17 62.3 0.8 1.5e-16 60.7 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.1 CDI74387.1 - 4.3e-13 49.2 0.0 1.7e-11 44.0 0.0 2.4 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rep_fac_C PF08542.6 CDI74387.1 - 6.5e-11 42.0 0.0 2.1e-10 40.4 0.0 1.9 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA_22 PF13401.1 CDI74387.1 - 8.6e-08 32.3 0.0 8.3e-07 29.2 0.0 2.5 1 1 0 1 1 1 1 AAA domain AAA_11 PF13086.1 CDI74387.1 - 6.7e-07 29.1 0.5 1.5e-05 24.6 0.0 2.4 2 1 0 2 2 2 1 AAA domain AAA_14 PF13173.1 CDI74387.1 - 4e-06 26.7 0.0 9e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 CDI74387.1 - 7.4e-06 26.0 2.8 6.1e-05 23.0 0.2 2.8 2 1 0 2 2 2 1 AAA ATPase domain AAA_19 PF13245.1 CDI74387.1 - 9.9e-06 25.2 0.0 4.2e-05 23.2 0.0 2.1 1 0 0 1 1 1 1 Part of AAA domain RuvB_N PF05496.7 CDI74387.1 - 7.1e-05 21.9 0.1 0.00042 19.4 0.0 2.1 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_30 PF13604.1 CDI74387.1 - 0.00023 20.8 0.0 0.00023 20.8 0.0 2.0 2 0 0 2 2 1 1 AAA domain Rad17 PF03215.10 CDI74387.1 - 0.0024 16.6 0.0 0.004 15.8 0.0 1.3 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein DEAD PF00270.24 CDI74387.1 - 0.0037 16.7 0.1 0.081 12.4 0.0 2.5 1 1 0 2 2 2 1 DEAD/DEAH box helicase AAA_5 PF07728.9 CDI74387.1 - 0.0039 16.9 0.3 0.024 14.3 0.0 2.5 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 CDI74387.1 - 0.0071 15.5 0.2 0.15 11.2 0.0 2.7 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.1 CDI74387.1 - 0.013 15.3 1.1 0.039 13.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.1 CDI74387.1 - 0.014 15.4 0.4 0.6 10.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.8 CDI74387.1 - 0.022 13.6 0.0 0.039 12.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_24 PF13479.1 CDI74387.1 - 0.03 13.9 0.0 0.064 12.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain ResIII PF04851.10 CDI74387.1 - 0.034 13.9 0.6 0.22 11.3 0.0 2.3 2 1 1 3 3 2 0 Type III restriction enzyme, res subunit AAA_10 PF12846.2 CDI74387.1 - 0.049 13.0 0.2 6.9 6.0 0.0 2.3 1 1 1 2 2 2 0 AAA-like domain AAA_3 PF07726.6 CDI74387.1 - 0.051 13.1 0.1 0.31 10.6 0.0 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 CDI74387.1 - 0.08 12.3 0.3 0.53 9.6 0.1 2.3 2 1 1 3 3 2 0 AAA domain Not3 PF04065.10 CDI74389.1 - 0.0001 21.6 3.1 0.00012 21.4 2.1 1.2 1 0 0 1 1 1 1 Not1 N-terminal domain, CCR4-Not complex component Syntaxin-6_N PF09177.6 CDI74389.1 - 0.013 15.9 3.9 0.018 15.4 2.6 1.3 1 1 0 1 1 1 0 Syntaxin 6, N-terminal Filament PF00038.16 CDI74389.1 - 0.026 13.9 10.3 0.046 13.1 7.1 1.4 1 1 0 1 1 1 0 Intermediate filament protein Tautomerase_2 PF14552.1 CDI74389.1 - 0.032 14.2 0.1 0.047 13.6 0.1 1.3 1 0 0 1 1 1 0 Tautomerase enzyme DUF3006 PF11213.3 CDI74389.1 - 0.054 13.2 0.1 0.054 13.2 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3006) DUF3907 PF13047.1 CDI74389.1 - 0.084 12.4 0.6 0.3 10.7 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3907) CDC37_N PF03234.9 CDI74389.1 - 0.088 13.1 3.8 0.12 12.7 2.7 1.1 1 0 0 1 1 1 0 Cdc37 N terminal kinase binding TetR PF13972.1 CDI74389.1 - 0.11 11.9 1.1 0.13 11.7 0.1 1.7 2 0 0 2 2 2 0 Bacterial transcriptional repressor ACCA PF03255.9 CDI74389.1 - 0.17 11.3 4.7 2.5 7.6 0.4 2.1 1 1 1 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit Baculo_PEP_C PF04513.7 CDI74389.1 - 0.19 11.5 2.5 0.25 11.1 1.7 1.3 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus TPR_6 PF13174.1 CDI74389.1 - 0.21 12.1 1.3 8.5 7.0 0.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat Cob_adeno_trans PF01923.13 CDI74389.1 - 0.25 11.1 3.9 0.27 11.0 2.4 1.3 1 1 0 1 1 1 0 Cobalamin adenosyltransferase TPR_12 PF13424.1 CDI74389.1 - 0.38 10.7 3.5 0.7 9.8 2.4 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF4238 PF14022.1 CDI74389.1 - 0.41 9.8 1.8 0.48 9.6 1.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4238) DUF1640 PF07798.6 CDI74389.1 - 0.49 10.4 4.7 0.81 9.6 3.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) DUF342 PF03961.8 CDI74389.1 - 0.56 8.5 4.1 0.65 8.3 2.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) GAS PF13851.1 CDI74389.1 - 0.6 9.2 10.9 0.17 11.0 5.2 1.6 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding Atg14 PF10186.4 CDI74389.1 - 0.67 8.8 7.4 0.49 9.2 3.9 1.5 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF1664 PF07889.7 CDI74389.1 - 0.83 9.4 3.1 2.2 8.0 2.2 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) IncA PF04156.9 CDI74389.1 - 0.88 9.1 15.8 1.5 8.3 11.0 1.4 1 1 0 1 1 1 0 IncA protein FliJ PF02050.11 CDI74389.1 - 0.89 9.6 15.5 2.4 8.2 10.4 1.9 1 1 1 2 2 2 0 Flagellar FliJ protein Exonuc_VII_L PF02601.10 CDI74389.1 - 0.96 8.5 4.6 1.1 8.4 3.2 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Spc7 PF08317.6 CDI74389.1 - 1 7.9 8.1 0.46 9.0 3.6 1.4 1 1 0 1 1 1 0 Spc7 kinetochore protein OmpH PF03938.9 CDI74389.1 - 2 8.3 12.8 1.5 8.7 8.0 1.3 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) Tropomyosin_1 PF12718.2 CDI74389.1 - 2.5 7.9 14.7 2 8.2 6.2 2.6 1 1 1 2 2 2 0 Tropomyosin like FlxA PF14282.1 CDI74389.1 - 2.8 7.9 8.6 0.78 9.7 3.5 1.8 2 0 0 2 2 2 0 FlxA-like protein ADIP PF11559.3 CDI74389.1 - 3.1 7.6 12.5 1.5 8.6 6.6 1.8 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Mnd1 PF03962.10 CDI74389.1 - 3.8 7.1 10.4 12 5.5 7.2 1.7 1 1 0 1 1 1 0 Mnd1 family Prefoldin PF02996.12 CDI74389.1 - 6.9 6.3 13.4 2.3 7.8 1.1 2.9 2 1 1 3 3 3 0 Prefoldin subunit AAA_23 PF13476.1 CDI74389.1 - 7 6.9 10.8 11 6.2 7.5 1.3 1 0 0 1 1 1 0 AAA domain Microtub_assoc PF07989.6 CDI74389.1 - 7.8 6.4 9.2 13 5.7 1.7 2.9 1 1 1 2 2 2 0 Microtubule associated Cation_efflux PF01545.16 CDI74390.1 - 1.8e-49 168.3 14.1 4.6e-49 167.0 9.8 1.6 1 1 0 1 1 1 1 Cation efflux family Daxx PF03344.10 CDI74391.1 - 0.42 9.0 8.6 0.6 8.5 6.0 1.1 1 0 0 1 1 1 0 Daxx Family DNA_pol_A_exo1 PF01612.15 CDI74392.1 - 1.4e-35 122.3 0.0 2.9e-35 121.3 0.0 1.6 1 0 0 1 1 1 1 3'-5' exonuclease HRDC PF00570.18 CDI74392.1 - 8.3e-14 51.0 0.0 1.8e-13 50.0 0.0 1.6 1 0 0 1 1 1 1 HRDC domain Ctr PF04145.10 CDI74392.1 - 2.4 8.1 11.7 2.7 8.0 0.1 4.2 4 1 0 4 4 4 0 Ctr copper transporter family RNase_T PF00929.19 CDI74393.1 - 5.7e-27 95.0 0.1 1.3e-14 54.7 0.0 2.1 1 1 1 2 2 2 2 Exonuclease DUF3186 PF11382.3 CDI74393.1 - 0.016 14.3 0.1 0.023 13.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3186) PGAP1 PF07819.8 CDI74393.1 - 0.028 14.0 0.2 0.066 12.7 0.1 1.6 1 1 1 2 2 2 0 PGAP1-like protein Ndc80_HEC PF03801.8 CDI74393.1 - 0.074 12.4 0.3 2.1 7.7 0.1 2.6 1 1 2 3 3 3 0 HEC/Ndc80p family GYF PF02213.11 CDI74394.1 - 3.8e-15 55.2 0.1 1.6e-14 53.2 0.0 2.1 1 0 0 1 1 1 1 GYF domain eIF2A PF08662.6 CDI74395.1 - 2.5e-40 138.2 0.0 2.3e-34 118.7 0.0 3.5 4 0 0 4 4 4 2 Eukaryotic translation initiation factor eIF2A TRAM_LAG1_CLN8 PF03798.11 CDI74396.1 - 1.1e-16 61.0 7.9 1.7e-16 60.3 5.4 1.2 1 0 0 1 1 1 1 TLC domain IL32 PF15225.1 CDI74397.1 - 0.062 13.2 1.8 0.14 12.1 0.1 2.2 2 0 0 2 2 2 0 Interleukin 32 AAA_23 PF13476.1 CDI74398.1 - 1.7 8.9 5.4 6.6 6.9 3.7 1.8 1 1 0 1 1 1 0 AAA domain Ribosomal_60s PF00428.14 CDI74398.1 - 1.8 9.0 20.4 0.47 10.8 7.2 2.6 2 0 0 2 2 2 0 60s Acidic ribosomal protein Arf PF00025.16 CDI74399.1 - 1.9e-21 76.0 0.0 4.4e-19 68.3 0.0 2.1 1 1 1 2 2 2 2 ADP-ribosylation factor family G-alpha PF00503.15 CDI74399.1 - 1.3e-05 24.0 0.0 1.7e-05 23.6 0.0 1.1 1 0 0 1 1 1 1 G-protein alpha subunit Miro PF08477.8 CDI74399.1 - 0.003 18.0 0.0 0.0041 17.5 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Peptidase_A24 PF01478.13 CDI74399.1 - 0.15 12.2 2.1 0.15 12.2 1.4 1.3 1 1 0 1 1 1 0 Type IV leader peptidase family Ribosomal_60s PF00428.14 CDI74399.1 - 0.57 10.6 12.5 1.3 9.4 8.6 1.6 1 0 0 1 1 1 0 60s Acidic ribosomal protein RRM_1 PF00076.17 CDI74401.1 - 7.2e-07 28.7 0.0 1.9e-06 27.3 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CDI74401.1 - 0.0013 18.7 0.0 0.0013 18.7 0.0 2.2 2 1 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CDI74401.1 - 0.0075 16.0 0.0 0.0075 16.0 0.0 2.4 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4523 PF15023.1 CDI74401.1 - 0.0096 15.4 0.7 0.02 14.3 0.5 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF4523) PAT1 PF09770.4 CDI74401.1 - 0.42 8.7 36.9 0.009 14.3 21.0 1.4 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 AAA_23 PF13476.1 CDI74401.1 - 4.4 7.5 12.5 8.6 6.6 8.6 1.6 1 0 0 1 1 1 0 AAA domain CDK2AP PF09806.4 CDI74401.1 - 4.9 7.3 0.0 4.9 7.3 0.0 4.7 3 2 1 4 4 4 0 Cyclin-dependent kinase 2-associated protein Helicase_C PF00271.26 CDI74402.1 - 5.4e-15 55.0 0.0 5.4e-15 55.0 0.0 5.9 6 0 0 6 6 6 1 Helicase conserved C-terminal domain Caldesmon PF02029.10 CDI74402.1 - 0.00095 17.6 10.6 0.00095 17.6 7.4 7.4 5 1 2 7 7 7 1 Caldesmon DUF1777 PF08648.7 CDI74403.1 - 9.7 5.8 162.1 1.5e+04 -68.7 112.4 3.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1777) AAA_23 PF13476.1 CDI74405.1 - 0.056 13.7 2.6 0.068 13.4 1.8 1.1 1 0 0 1 1 1 0 AAA domain Spt20 PF12090.3 CDI74405.1 - 0.13 11.5 2.6 0.19 11.0 1.8 1.3 1 0 0 1 1 1 0 Spt20 family FimP PF09766.4 CDI74405.1 - 0.44 9.5 8.8 0.61 9.0 6.1 1.1 1 0 0 1 1 1 0 Fms-interacting protein FAM196 PF15265.1 CDI74405.1 - 2.5 7.2 19.2 3 6.9 13.3 1.2 1 0 0 1 1 1 0 FAM196 family RNA_pol_Rpb1_5 PF04998.12 CDI74407.1 - 0.5 9.5 0.0 0.5 9.5 0.0 3.1 1 1 2 3 3 3 0 RNA polymerase Rpb1, domain 5 RNase_PH PF01138.16 CDI74410.1 - 3.1e-14 53.4 0.1 2.3e-13 50.6 0.0 2.0 1 1 0 1 1 1 1 3' exoribonuclease family, domain 1 Med3 PF11593.3 CDI74410.1 - 0.18 11.0 0.6 0.23 10.6 0.4 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal FLO_LFY PF01698.11 CDI74411.1 - 5 5.8 29.3 5.5 5.7 20.3 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein DUF1510 PF07423.6 CDI74411.1 - 9 5.5 37.2 11 5.2 25.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Pkinase PF00069.20 CDI74412.1 - 1.5e-52 178.3 0.0 1.5e-52 178.3 0.0 3.2 3 1 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDI74412.1 - 6.3e-21 74.6 0.2 1.9e-20 73.0 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Utp14 PF04615.8 CDI74414.1 - 2.2 6.3 43.8 2.9 5.9 30.3 1.1 1 0 0 1 1 1 0 Utp14 protein Gly-zipper_OmpA PF13436.1 CDI74416.1 - 5 6.8 28.1 6.1 6.5 19.5 1.2 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain FAM60A PF15396.1 CDI74417.1 - 0.0095 15.7 0.8 0.0095 15.7 0.5 2.7 2 1 1 3 3 2 1 Protein Family FAM60A DUF1510 PF07423.6 CDI74417.1 - 0.019 14.3 33.8 0.016 14.5 16.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) Suf PF05843.9 CDI74417.1 - 0.02 14.6 52.0 0.45 10.1 7.3 2.4 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) TerC PF03741.11 CDI74417.1 - 0.26 10.7 0.0 0.26 10.7 0.0 2.7 3 0 0 3 3 3 0 Integral membrane protein TerC family DUF2201_N PF13203.1 CDI74417.1 - 0.43 9.7 35.9 0.19 10.8 16.0 2.4 2 0 0 2 2 2 0 Putative metallopeptidase domain LMBR1 PF04791.11 CDI74417.1 - 0.54 8.7 0.0 0.54 8.7 0.0 2.1 1 1 1 2 2 1 0 LMBR1-like membrane protein GAGA_bind PF06217.7 CDI74417.1 - 0.71 9.7 36.8 0.11 12.4 16.4 2.1 2 0 0 2 2 2 0 GAGA binding protein-like family Ycf1 PF05758.7 CDI74417.1 - 0.73 7.4 30.1 0.034 11.8 11.6 2.1 2 0 0 2 2 2 0 Ycf1 eIF-3_zeta PF05091.7 CDI74417.1 - 2.4 6.6 46.1 3.1 6.2 3.2 2.3 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) CDC45 PF02724.9 CDI74417.1 - 9.1 4.1 41.1 3.4 5.6 21.4 2.2 2 0 0 2 2 2 0 CDC45-like protein Med15 PF09606.5 CDI74417.1 - 9.1 4.3 119.3 0.3 9.2 14.6 2.0 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal Med15 PF09606.5 CDI74418.1 - 0.00064 18.0 61.2 0.00064 18.0 42.5 12.5 5 2 4 9 9 9 3 ARC105 or Med15 subunit of Mediator complex non-fungal SR-25 PF10500.4 CDI74418.1 - 0.0029 17.0 6.6 0.0029 17.0 4.6 20.4 15 5 5 20 20 20 5 Nuclear RNA-splicing-associated protein Dehydrin PF00257.14 CDI74418.1 - 0.12 12.7 0.0 0.12 12.7 0.0 21.5 9 8 3 12 12 12 0 Dehydrin TLC PF03219.9 CDI74418.1 - 1.9 6.8 1.5 6.7 5.0 1.1 1.9 1 0 0 1 1 1 0 TLC ATP/ADP transporter PAT1 PF09770.4 CDI74419.1 - 1.1 7.3 27.1 1.3 7.1 18.8 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 CENP-H PF05837.7 CDI74419.1 - 3.7 7.7 12.6 3.8 7.7 5.6 2.1 2 0 0 2 2 2 0 Centromere protein H (CENP-H) Neur_chan_memb PF02932.11 CDI74419.1 - 4 7.2 5.1 4.6 7.0 3.6 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region AAA_23 PF13476.1 CDI74419.1 - 9.4 6.4 13.6 14 5.9 9.4 1.2 1 0 0 1 1 1 0 AAA domain DUF4366 PF14283.1 CDI74421.1 - 0.0026 17.2 4.0 0.0026 17.2 2.8 4.9 3 1 1 4 4 4 1 Domain of unknown function (DUF4366) DUF1510 PF07423.6 CDI74422.1 - 1.6 8.0 26.0 1.6 8.0 18.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Kei1 PF08552.6 CDI74422.1 - 8.6 5.9 18.2 11 5.6 12.6 1.3 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 LMBR1 PF04791.11 CDI74423.1 - 0.11 11.0 7.1 0.9 8.0 0.4 2.7 1 1 0 2 2 2 0 LMBR1-like membrane protein HHH_5 PF14520.1 CDI74424.1 - 0.16 12.1 4.7 0.33 11.1 1.0 2.9 2 1 0 2 2 2 0 Helix-hairpin-helix domain DUF2392 PF10288.4 CDI74424.1 - 0.48 10.7 3.4 29 5.0 0.0 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF2392) DUF2031 PF09592.5 CDI74426.1 - 0.51 9.4 5.7 0.75 8.8 3.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2031) SpoIIIAH PF12685.2 CDI74426.1 - 1.3 8.4 28.3 1.3 8.4 6.6 2.8 2 1 0 2 2 2 0 SpoIIIAH-like protein Rtf2 PF04641.7 CDI74426.1 - 1.8 7.6 20.6 0.53 9.4 8.8 2.1 2 0 0 2 2 2 0 Rtf2 RING-finger DUF1510 PF07423.6 CDI74426.1 - 2.4 7.4 22.8 8.6 5.6 12.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) Herpes_UL87 PF03043.9 CDI74426.1 - 2.6 6.3 18.9 3.3 5.9 13.1 1.0 1 0 0 1 1 1 0 Herpesvirus UL87 family G-alpha PF00503.15 CDI74426.1 - 3.2 6.3 18.3 4.4 5.8 10.4 2.0 2 0 0 2 2 2 0 G-protein alpha subunit DUF912 PF06024.7 CDI74426.1 - 4.4 7.4 23.5 0.12 12.4 4.4 3.3 2 1 1 3 3 3 0 Nucleopolyhedrovirus protein of unknown function (DUF912) FAM60A PF15396.1 CDI74426.1 - 7.5 6.2 19.5 4.9 6.8 10.8 2.1 2 0 0 2 2 2 0 Protein Family FAM60A DDRGK PF09756.4 CDI74427.1 - 0.062 12.7 19.1 0.12 11.7 13.2 1.5 1 0 0 1 1 1 0 DDRGK domain PAT1 PF09770.4 CDI74427.1 - 0.069 11.3 42.6 0.086 11.0 29.5 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Asp-B-Hydro_N PF05279.6 CDI74427.1 - 0.57 9.9 10.9 0.74 9.6 7.5 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region eIF3_subunit PF08597.5 CDI74427.1 - 3.2 7.2 13.8 5.2 6.5 9.6 1.3 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit BUD22 PF09073.5 CDI74428.1 - 0.23 10.5 15.9 0.42 9.6 11.0 1.3 1 0 0 1 1 1 0 BUD22 DEAD PF00270.24 CDI74429.1 - 1.1e-05 25.0 25.4 0.00067 19.1 0.0 4.0 3 2 1 4 4 4 3 DEAD/DEAH box helicase DUF3155 PF11352.3 CDI74429.1 - 0.047 13.9 0.1 0.047 13.9 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3155) Helicase_C PF00271.26 CDI74432.1 - 9.7e-16 57.4 0.0 2.6e-15 56.0 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HSP9_HSP12 PF04119.7 CDI74432.1 - 0.028 14.4 1.3 0.084 12.9 0.9 1.8 1 0 0 1 1 1 0 Heat shock protein 9/12 DUF3154 PF11351.3 CDI74432.1 - 0.84 9.3 5.7 0.73 9.5 0.9 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3154) Prothymosin PF03247.9 CDI74434.1 - 0.011 15.9 13.6 0.016 15.3 9.4 1.2 1 0 0 1 1 1 0 Prothymosin/parathymosin family DUF4179 PF13786.1 CDI74434.1 - 0.021 15.0 0.0 0.029 14.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4179) DUF4604 PF15377.1 CDI74434.1 - 0.033 14.4 19.8 0.038 14.1 5.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4604) GN3L_Grn1 PF08701.6 CDI74434.1 - 0.08 12.8 27.1 0.13 12.2 18.8 1.3 1 1 0 1 1 1 0 GNL3L/Grn1 putative GTPase NST1 PF13945.1 CDI74434.1 - 0.2 11.7 22.0 0.34 10.9 15.3 1.4 1 1 0 1 1 1 0 Salt tolerance down-regulator SOBP PF15279.1 CDI74434.1 - 0.23 11.8 11.5 0.26 11.6 8.0 1.0 1 0 0 1 1 1 0 Sine oculis-binding protein Daxx PF03344.10 CDI74434.1 - 0.27 9.6 18.2 0.33 9.4 12.6 1.0 1 0 0 1 1 1 0 Daxx Family AAA_23 PF13476.1 CDI74434.1 - 0.37 11.1 16.3 0.43 10.8 11.3 1.1 1 0 0 1 1 1 0 AAA domain Med15 PF09606.5 CDI74434.1 - 0.39 8.8 22.6 0.43 8.7 15.7 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal AUX_IAA PF02309.11 CDI74434.1 - 0.4 10.3 12.8 0.54 9.9 8.8 1.2 1 0 0 1 1 1 0 AUX/IAA family SAGA-Tad1 PF12767.2 CDI74434.1 - 0.45 10.1 14.5 0.51 9.9 10.1 1.0 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit Tau95 PF09734.4 CDI74434.1 - 0.68 9.1 11.2 0.81 8.9 7.8 1.0 1 0 0 1 1 1 0 RNA polymerase III transcription factor (TF)IIIC subunit PBP1_TM PF14812.1 CDI74434.1 - 0.71 10.2 11.9 2.8 8.3 2.3 2.1 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF4647 PF15504.1 CDI74434.1 - 0.82 8.4 16.8 0.95 8.2 11.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4647) Zip PF02535.17 CDI74434.1 - 1.1 8.2 7.5 1.2 8.0 5.2 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Cas_CT1975 PF09344.5 CDI74434.1 - 1.4 8.1 9.0 1.7 7.9 6.3 1.1 1 0 0 1 1 1 0 CT1975-like protein DUF1510 PF07423.6 CDI74434.1 - 1.9 7.8 20.0 2.7 7.2 13.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) FNIP_N PF14636.1 CDI74434.1 - 1.9 8.9 11.7 2.3 8.7 8.1 1.1 1 0 0 1 1 1 0 Folliculin-interacting protein N-terminus Hid1 PF12722.2 CDI74434.1 - 2.5 5.6 12.7 2.8 5.5 8.8 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Suf PF05843.9 CDI74434.1 - 2.5 7.7 16.9 3 7.4 11.7 1.0 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) OmpH PF03938.9 CDI74434.1 - 2.7 7.9 25.7 3.2 7.6 17.8 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) CMV_1a PF12467.3 CDI74434.1 - 2.9 8.2 12.3 3.6 7.9 8.5 1.2 1 0 0 1 1 1 0 Cucumber mosaic virus 1a protein family Conotoxin PF02950.12 CDI74434.1 - 3.3 8.5 11.7 5 8.0 2.8 2.1 2 0 0 2 2 2 0 Conotoxin SprA-related PF12118.3 CDI74434.1 - 3.7 6.7 27.4 4.6 6.4 19.0 1.1 1 0 0 1 1 1 0 SprA-related family WBS_methylT PF12589.3 CDI74434.1 - 3.8 8.0 20.7 2.7 8.5 3.3 2.1 2 0 0 2 2 2 0 Methyltransferase involved in Williams-Beuren syndrome DUF1676 PF07898.8 CDI74434.1 - 3.9 7.8 11.4 1.8 8.8 1.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1676) Presenilin PF01080.12 CDI74434.1 - 4.1 6.1 9.4 4.6 5.9 6.5 1.0 1 0 0 1 1 1 0 Presenilin ETRAMP PF09716.5 CDI74434.1 - 4.6 7.2 8.1 0.31 10.9 1.5 1.9 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) CDK5_activator PF03261.10 CDI74434.1 - 5.1 6.3 9.2 6.8 5.9 6.4 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein Spore_coat_CotO PF14153.1 CDI74434.1 - 5.3 6.4 24.5 7.3 5.9 17.0 1.2 1 0 0 1 1 1 0 Spore coat protein CotO DUF4175 PF13779.1 CDI74434.1 - 5.4 4.5 25.6 5.9 4.4 17.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) PBP_sp32 PF07222.7 CDI74434.1 - 5.5 6.0 22.3 6.9 5.7 15.5 1.1 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Anoctamin PF04547.7 CDI74434.1 - 7.2 5.1 7.6 8.8 4.8 5.3 1.2 1 0 0 1 1 1 0 Calcium-activated chloride channel FAM60A PF15396.1 CDI74434.1 - 7.7 6.2 15.6 9.2 5.9 10.8 1.1 1 0 0 1 1 1 0 Protein Family FAM60A Rtf2 PF04641.7 CDI74434.1 - 8 5.5 19.4 11 5.1 13.5 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger NPR3 PF03666.8 CDI74434.1 - 8.1 4.8 15.5 9.5 4.6 10.8 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF3381 PF11861.3 CDI74434.1 - 9.2 5.7 24.1 5.7 6.4 4.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3381) DUF3959 PF13105.1 CDI74434.1 - 9.2 5.5 11.6 11 5.2 8.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3959) PAT1 PF09770.4 CDI74436.1 - 2.5e-05 22.7 32.1 2.9e-05 22.5 22.3 1.2 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 Macoilin PF09726.4 CDI74436.1 - 4.2e-05 22.0 44.0 6.1e-05 21.5 30.5 1.1 1 0 0 1 1 1 1 Transmembrane protein DUF342 PF03961.8 CDI74436.1 - 0.067 11.5 11.3 0.082 11.3 7.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) YjgP_YjgQ PF03739.9 CDI74436.1 - 0.94 8.1 6.2 1.1 7.8 4.3 1.2 1 0 0 1 1 1 0 Predicted permease YjgP/YjgQ family DUF4175 PF13779.1 CDI74436.1 - 1.1 6.9 55.0 1.5 6.4 38.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) DUF4071 PF13281.1 CDI74436.1 - 2 7.1 15.4 2.8 6.6 10.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4071) Hist_deacetyl PF00850.14 CDI74436.1 - 2.9 7.0 8.1 5.3 6.2 5.6 1.4 1 0 0 1 1 1 0 Histone deacetylase domain DUF3584 PF12128.3 CDI74436.1 - 5.9 4.0 40.4 7.5 3.7 28.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) WD40 PF00400.27 CDI74437.1 - 6e-09 35.4 5.5 0.023 14.5 0.0 4.7 5 0 0 5 5 5 3 WD domain, G-beta repeat Gmad1 PF10647.4 CDI74437.1 - 1.2e-05 24.8 3.4 0.044 13.1 0.0 2.7 1 1 2 3 3 3 2 Lipoprotein LpqB beta-propeller domain Sulfotransfer_3 PF13469.1 CDI74437.1 - 0.1 13.5 0.2 0.17 12.7 0.1 1.4 1 0 0 1 1 1 0 Sulfotransferase family Mob1_phocein PF03637.12 CDI74438.1 - 3.7e-10 39.7 0.0 8.2e-05 22.3 0.0 3.1 3 0 0 3 3 3 3 Mob1/phocein family EIF_2_alpha PF07541.7 CDI74439.1 - 5.9e-26 90.4 0.0 9.5e-26 89.7 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.18 CDI74439.1 - 1.5e-09 37.7 0.9 3.1e-09 36.7 0.1 2.0 2 0 0 2 2 2 1 S1 RNA binding domain Phage_1_1 PF08200.6 CDI74439.1 - 0.12 12.5 0.1 0.33 11.1 0.1 1.7 1 0 0 1 1 1 0 Bacteriophage 1.1 Protein DUF3530 PF12048.3 CDI74440.1 - 0.02 13.8 15.6 0.045 12.7 10.8 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3530) SID-1_RNA_chan PF13965.1 CDI74440.1 - 0.041 12.0 1.3 0.047 11.8 0.9 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Conotoxin PF02950.12 CDI74440.1 - 0.047 14.5 0.4 0.047 14.5 0.3 2.3 1 1 1 2 2 1 0 Conotoxin DUF913 PF06025.7 CDI74440.1 - 0.15 10.7 1.7 0.17 10.6 1.1 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DUF3357 PF11837.3 CDI74440.1 - 0.19 11.6 4.3 0.21 11.4 0.0 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF3357) TMEM154 PF15102.1 CDI74440.1 - 0.21 11.2 0.0 0.21 11.2 0.0 2.4 2 1 0 2 2 1 0 TMEM154 protein family DUF1510 PF07423.6 CDI74440.1 - 0.26 10.6 8.9 0.4 10.0 6.2 1.2 1 1 0 1 1 1 0 Protein of unknown function (DUF1510) GRP PF07172.6 CDI74440.1 - 0.29 11.6 0.0 0.29 11.6 0.0 2.2 1 1 0 2 2 2 0 Glycine rich protein family DUF4220 PF13968.1 CDI74440.1 - 0.39 9.7 2.4 0.44 9.5 1.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4220) FAM176 PF14851.1 CDI74440.1 - 0.66 9.6 6.0 5 6.7 1.8 2.1 2 0 0 2 2 2 0 FAM176 family Neur_chan_memb PF02932.11 CDI74440.1 - 0.72 9.6 4.7 0.97 9.2 3.2 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Presenilin PF01080.12 CDI74440.1 - 0.79 8.4 4.4 0.94 8.2 3.0 1.1 1 0 0 1 1 1 0 Presenilin DUF4446 PF14584.1 CDI74440.1 - 0.82 9.4 6.7 13 5.5 3.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) DUF4407 PF14362.1 CDI74440.1 - 1.1 8.0 13.7 1.5 7.6 9.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) SPX PF03105.14 CDI74440.1 - 1.3 8.7 11.3 1.6 8.4 7.8 1.0 1 0 0 1 1 1 0 SPX domain DUF3450 PF11932.3 CDI74440.1 - 1.4 8.0 21.3 1.8 7.7 14.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) AAA_23 PF13476.1 CDI74440.1 - 1.4 9.1 21.1 1.8 8.8 14.6 1.0 1 0 0 1 1 1 0 AAA domain Anoctamin PF04547.7 CDI74440.1 - 2 6.9 5.2 2.3 6.7 3.6 1.1 1 0 0 1 1 1 0 Calcium-activated chloride channel Suf PF05843.9 CDI74440.1 - 2 8.0 17.2 2.8 7.5 11.9 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) FNIP_N PF14636.1 CDI74440.1 - 2.1 8.8 11.3 3.1 8.2 7.9 1.2 1 0 0 1 1 1 0 Folliculin-interacting protein N-terminus DUF3959 PF13105.1 CDI74440.1 - 2.6 7.3 7.3 2.9 7.1 5.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3959) EphA2_TM PF14575.1 CDI74440.1 - 3.8 7.9 0.0 3.8 7.9 0.0 2.5 2 1 0 2 2 1 0 Ephrin type-A receptor 2 transmembrane domain Band_3_cyto PF07565.8 CDI74440.1 - 4.5 6.7 12.3 5.9 6.3 8.5 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Corona_nucleoca PF00937.13 CDI74440.1 - 4.7 6.0 17.9 5.8 5.7 12.4 1.0 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein Folate_carrier PF01770.13 CDI74440.1 - 6.4 5.1 9.9 9.3 4.6 6.9 1.3 1 1 0 1 1 1 0 Reduced folate carrier Herpes_DNAp_acc PF04929.7 CDI74440.1 - 8.6 5.2 11.0 11 4.8 7.6 1.0 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Sec62 PF03839.11 CDI74440.1 - 9.5 5.5 9.1 13 5.1 6.3 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 Daxx PF03344.10 CDI74441.1 - 0.42 9.0 45.4 0.56 8.6 31.5 1.1 1 0 0 1 1 1 0 Daxx Family DUF1510 PF07423.6 CDI74442.1 - 3.9e-05 23.1 17.9 5e-05 22.7 12.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) Zip PF02535.17 CDI74442.1 - 0.0032 16.5 3.9 0.0035 16.3 2.7 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter Neur_chan_memb PF02932.11 CDI74442.1 - 0.0045 16.8 15.6 0.0055 16.6 10.8 1.0 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region PAT1 PF09770.4 CDI74442.1 - 0.016 13.4 45.9 0.017 13.4 31.8 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 GPCR_chapero_1 PF11904.3 CDI74442.1 - 0.025 13.7 17.6 0.027 13.6 12.2 1.0 1 0 0 1 1 1 0 GPCR-chaperone Pneumo_phosprot PF02478.11 CDI74442.1 - 0.065 12.7 7.5 0.078 12.5 5.2 1.1 1 0 0 1 1 1 0 Pneumovirus phosphoprotein RR_TM4-6 PF06459.7 CDI74442.1 - 0.082 12.7 22.2 0.12 12.2 15.4 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DDHD PF02862.12 CDI74442.1 - 0.1 12.3 16.7 0.14 11.9 11.6 1.3 1 0 0 1 1 1 0 DDHD domain Paf1 PF03985.8 CDI74442.1 - 0.11 11.2 22.8 0.12 11.0 15.8 1.0 1 0 0 1 1 1 0 Paf1 SAPS PF04499.10 CDI74442.1 - 0.13 10.8 18.8 0.16 10.6 13.1 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Herpes_DNAp_acc PF04929.7 CDI74442.1 - 0.15 10.9 17.8 0.18 10.7 12.4 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor GAGA_bind PF06217.7 CDI74442.1 - 0.17 11.8 23.2 0.2 11.5 16.1 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family RNase_H2-Ydr279 PF09468.5 CDI74442.1 - 0.22 10.7 11.8 0.32 10.1 8.2 1.2 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) TFIIA PF03153.8 CDI74442.1 - 0.23 11.3 33.5 0.24 11.2 23.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Ycf1 PF05758.7 CDI74442.1 - 0.23 9.1 22.6 0.26 8.9 15.7 1.0 1 0 0 1 1 1 0 Ycf1 Caldesmon PF02029.10 CDI74442.1 - 0.29 9.5 22.8 0.35 9.2 15.8 1.1 1 0 0 1 1 1 0 Caldesmon Glyco_transf_15 PF01793.11 CDI74442.1 - 0.38 9.6 18.8 0.54 9.1 13.0 1.3 1 0 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase NARP1 PF12569.3 CDI74442.1 - 0.41 9.3 21.8 0.54 8.9 15.1 1.3 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DDRGK PF09756.4 CDI74442.1 - 0.56 9.5 34.7 0.83 9.0 24.1 1.2 1 0 0 1 1 1 0 DDRGK domain Presenilin PF01080.12 CDI74442.1 - 0.71 8.6 16.2 0.86 8.3 11.2 1.1 1 0 0 1 1 1 0 Presenilin DUF2052 PF09747.4 CDI74442.1 - 0.73 9.7 27.8 0.91 9.4 19.3 1.1 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) SARG PF15385.1 CDI74442.1 - 0.75 9.0 26.6 0.88 8.8 18.4 1.0 1 0 0 1 1 1 0 Specifically androgen-regulated gene protein HemX PF04375.9 CDI74442.1 - 0.8 8.2 32.3 1.1 7.7 22.4 1.3 1 1 0 1 1 1 0 HemX FLO_LFY PF01698.11 CDI74442.1 - 0.96 8.2 21.9 1.1 7.9 15.2 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein Hid1 PF12722.2 CDI74442.1 - 1 6.9 23.0 1.2 6.7 16.0 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF342 PF03961.8 CDI74442.1 - 1.2 7.4 15.4 1.2 7.4 10.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Med15 PF09606.5 CDI74442.1 - 1.4 7.0 67.1 1.7 6.7 46.5 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Peptidase_S49_N PF08496.5 CDI74442.1 - 1.5 8.5 27.6 54 3.5 19.1 2.1 1 1 0 1 1 1 0 Peptidase family S49 N-terminal Mem_trans PF03547.13 CDI74442.1 - 1.5 7.0 10.0 1.9 6.6 6.9 1.1 1 0 0 1 1 1 0 Membrane transport protein AUX_IAA PF02309.11 CDI74442.1 - 1.6 8.4 20.6 1.9 8.1 14.3 1.2 1 0 0 1 1 1 0 AUX/IAA family RP-C_C PF11800.3 CDI74442.1 - 1.7 8.3 21.4 2.2 7.9 14.9 1.2 1 0 0 1 1 1 0 Replication protein C C-terminal region DUF4220 PF13968.1 CDI74442.1 - 1.7 7.6 9.7 2 7.4 6.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4220) Phage_GPO PF05929.6 CDI74442.1 - 1.8 7.7 20.5 1.9 7.7 14.2 1.1 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase GTA_TIM PF13547.1 CDI74442.1 - 1.8 7.4 9.6 2.3 7.1 6.7 1.1 1 0 0 1 1 1 0 GTA TIM-barrel-like domain DUF4045 PF13254.1 CDI74442.1 - 1.9 7.7 23.5 2.2 7.4 16.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) DUF3260 PF11658.3 CDI74442.1 - 1.9 6.5 14.3 2.7 6.0 9.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3260) CDC45 PF02724.9 CDI74442.1 - 2 6.3 23.5 2.6 5.9 16.3 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF1168 PF06658.7 CDI74442.1 - 2.6 7.5 33.5 3.7 7.0 23.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) Tim54 PF11711.3 CDI74442.1 - 2.8 6.4 16.4 4 5.9 11.4 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 SID-1_RNA_chan PF13965.1 CDI74442.1 - 2.8 6.0 12.2 3.3 5.7 8.4 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 APG6 PF04111.7 CDI74442.1 - 2.9 6.8 26.9 3.4 6.6 18.6 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 HCO3_cotransp PF00955.16 CDI74442.1 - 3.2 6.3 7.7 3.5 6.1 5.3 1.1 1 0 0 1 1 1 0 HCO3- transporter family TT_ORF1 PF02956.9 CDI74442.1 - 3.2 6.0 20.5 4.1 5.7 14.2 1.1 1 0 0 1 1 1 0 TT viral orf 1 Mgr1 PF08602.5 CDI74442.1 - 3.4 6.5 13.5 3.8 6.4 9.4 1.1 1 0 0 1 1 1 0 Mgr1-like, i-AAA protease complex subunit DUF853 PF05872.7 CDI74442.1 - 4.9 5.3 15.6 6.3 5.0 10.8 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) CKAP2_C PF15297.1 CDI74442.1 - 5.1 5.8 28.1 6.3 5.5 19.5 1.1 1 0 0 1 1 1 0 Cytoskeleton-associated protein 2 C-terminus FemAB PF02388.11 CDI74442.1 - 5.1 5.6 25.4 6.3 5.3 17.6 1.2 1 0 0 1 1 1 0 FemAB family HAUS6_N PF14661.1 CDI74442.1 - 5.3 6.3 26.4 6.7 5.9 18.3 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus MDFI PF15316.1 CDI74442.1 - 5.6 6.9 15.3 8.3 6.3 10.6 1.2 1 0 0 1 1 1 0 MyoD family inhibitor MMR1 PF08505.5 CDI74442.1 - 6 6.8 26.4 9.1 6.2 18.3 1.3 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein Selenoprotein_S PF06936.6 CDI74442.1 - 6 6.3 21.0 7.9 5.9 14.6 1.2 1 0 0 1 1 1 0 Selenoprotein S (SelS) Rtf2 PF04641.7 CDI74442.1 - 7.4 5.6 27.8 9.4 5.3 19.3 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger BTV_NS2 PF04514.7 CDI74442.1 - 7.8 5.2 20.2 9.9 4.9 14.0 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Membralin PF09746.4 CDI74442.1 - 8.9 5.2 11.7 10 5.0 8.1 1.1 1 0 0 1 1 1 0 Tumour-associated protein DUF1510 PF07423.6 CDI74444.1 - 0.0045 16.3 14.8 0.0054 16.1 10.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) Rifin_STEVOR PF02009.11 CDI74444.1 - 0.018 14.7 9.4 0.019 14.6 6.5 1.0 1 0 0 1 1 1 0 Rifin/stevor family BTV_NS2 PF04514.7 CDI74444.1 - 0.13 11.0 8.4 0.15 10.9 5.8 1.0 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Plasmodium_Vir PF05795.6 CDI74444.1 - 0.22 10.6 11.0 0.25 10.4 7.7 1.0 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Dicty_REP PF05086.7 CDI74444.1 - 0.22 9.2 20.6 0.26 8.9 14.3 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF4483 PF14825.1 CDI74444.1 - 0.23 11.1 16.8 0.31 10.7 11.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4483) PIH1 PF08190.7 CDI74444.1 - 0.32 10.3 21.3 0.35 10.2 14.8 1.0 1 0 0 1 1 1 0 pre-RNA processing PIH1/Nop17 RED_N PF07808.8 CDI74444.1 - 0.51 9.5 24.6 0.6 9.2 17.1 1.1 1 0 0 1 1 1 0 RED-like protein N-terminal region NPR3 PF03666.8 CDI74444.1 - 0.56 8.6 17.5 0.61 8.5 12.1 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Paramyxo_ncap PF00973.14 CDI74444.1 - 0.66 8.5 17.2 0.75 8.4 12.0 1.0 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Late_protein_L2 PF00513.13 CDI74444.1 - 0.74 8.5 14.0 0.88 8.3 9.7 1.0 1 0 0 1 1 1 0 Late Protein L2 Pap_E4 PF02711.9 CDI74444.1 - 0.75 10.6 25.8 0.26 12.1 12.7 2.0 1 1 1 2 2 2 0 E4 protein Zip PF02535.17 CDI74444.1 - 0.86 8.5 7.8 1.3 7.9 5.4 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter DUF3527 PF12043.3 CDI74444.1 - 0.87 9.0 15.8 1.1 8.7 10.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3527) NOA36 PF06524.7 CDI74444.1 - 0.94 8.6 8.6 1.1 8.4 5.9 1.0 1 0 0 1 1 1 0 NOA36 protein Miff PF05644.6 CDI74444.1 - 1 8.9 17.3 1.2 8.7 12.0 1.0 1 0 0 1 1 1 0 Mitochondrial and peroxisomal fission factor Mff DUF853 PF05872.7 CDI74444.1 - 1 7.6 11.2 1.1 7.4 7.8 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) FAM60A PF15396.1 CDI74444.1 - 1.1 8.9 17.4 1.4 8.6 12.0 1.0 1 0 0 1 1 1 0 Protein Family FAM60A GN3L_Grn1 PF08701.6 CDI74444.1 - 1.1 9.1 13.7 0.26 11.2 4.4 2.1 2 0 0 2 2 2 0 GNL3L/Grn1 putative GTPase DUF3807 PF12720.2 CDI74444.1 - 1.2 9.3 22.0 1.5 8.9 15.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) NABP PF07990.7 CDI74444.1 - 1.3 8.2 22.2 1.5 8.0 15.4 1.0 1 0 0 1 1 1 0 Nucleic acid binding protein NABP HCO3_cotransp PF00955.16 CDI74444.1 - 1.3 7.5 9.2 1.5 7.4 6.4 1.0 1 0 0 1 1 1 0 HCO3- transporter family UPF0565 PF10561.4 CDI74444.1 - 1.5 7.6 16.0 1.9 7.3 11.1 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0565 MAT1 PF06391.8 CDI74444.1 - 1.5 8.3 20.0 1.9 8.0 13.9 1.1 1 0 0 1 1 1 0 CDK-activating kinase assembly factor MAT1 Rtf2 PF04641.7 CDI74444.1 - 1.7 7.7 17.7 2 7.5 12.2 1.0 1 0 0 1 1 1 0 Rtf2 RING-finger Ycf1 PF05758.7 CDI74444.1 - 1.8 6.1 14.8 2 6.0 10.3 1.0 1 0 0 1 1 1 0 Ycf1 DUF1675 PF07897.6 CDI74444.1 - 1.9 8.3 19.3 2.2 8.0 13.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) DDRGK PF09756.4 CDI74444.1 - 2.3 7.5 18.3 2.9 7.2 12.7 1.1 1 0 0 1 1 1 0 DDRGK domain FHIPEP PF00771.15 CDI74444.1 - 2.5 6.3 9.5 3 6.0 6.6 1.2 1 0 0 1 1 1 0 FHIPEP family Na_trans_assoc PF06512.8 CDI74444.1 - 3 7.7 15.7 3.6 7.4 10.9 1.1 1 0 0 1 1 1 0 Sodium ion transport-associated DUF2052 PF09747.4 CDI74444.1 - 3.1 7.7 21.3 3.9 7.3 14.8 1.1 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) Macoilin PF09726.4 CDI74444.1 - 3.2 5.9 20.7 3.7 5.7 14.3 1.0 1 0 0 1 1 1 0 Transmembrane protein Consortin_C PF15281.1 CDI74444.1 - 3.3 7.2 7.0 3 7.3 2.5 2.0 1 1 1 2 2 2 0 Consortin C-terminus Neur_chan_memb PF02932.11 CDI74444.1 - 3.3 7.5 15.6 4 7.2 10.8 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region FAM91_C PF14648.1 CDI74444.1 - 4.4 6.0 12.1 5.1 5.8 8.4 1.1 1 0 0 1 1 1 0 FAM91 C-terminus Mcm10 PF09332.6 CDI74444.1 - 4.8 6.4 15.8 5.7 6.1 10.9 1.0 1 0 0 1 1 1 0 Mcm10 replication factor YABBY PF04690.8 CDI74444.1 - 5.4 7.2 15.0 7.7 6.7 10.4 1.3 1 0 0 1 1 1 0 YABBY protein SAPS PF04499.10 CDI74444.1 - 5.6 5.4 19.8 6.7 5.2 13.7 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF4045 PF13254.1 CDI74444.1 - 5.6 6.1 18.8 6.6 5.8 13.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) G-7-MTase PF12803.2 CDI74444.1 - 5.6 6.0 14.8 6.6 5.7 10.3 1.0 1 0 0 1 1 1 0 mRNA (guanine-7-)methyltransferase (G-7-MTase) VID27 PF08553.5 CDI74444.1 - 5.9 4.9 14.6 6.4 4.8 10.1 1.0 1 0 0 1 1 1 0 VID27 cytoplasmic protein Presenilin PF01080.12 CDI74444.1 - 6.4 5.4 16.8 7.5 5.2 11.7 1.1 1 0 0 1 1 1 0 Presenilin DUF4638 PF15472.1 CDI74444.1 - 7 6.1 14.1 8.3 5.9 9.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) DUF3260 PF11658.3 CDI74444.1 - 7.2 4.6 14.7 8.6 4.3 10.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3260) Mem_trans PF03547.13 CDI74444.1 - 7.2 4.7 12.8 7.8 4.6 8.9 1.1 1 0 0 1 1 1 0 Membrane transport protein TFIIA PF03153.8 CDI74444.1 - 7.6 6.3 32.3 9.9 5.9 22.4 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit GAGA_bind PF06217.7 CDI74444.1 - 8.8 6.1 19.0 10 6.0 13.2 1.0 1 0 0 1 1 1 0 GAGA binding protein-like family NST1 PF13945.1 CDI74444.1 - 9.3 6.2 26.3 11 5.9 18.2 1.1 1 0 0 1 1 1 0 Salt tolerance down-regulator SeqA PF03925.8 CDI74445.1 - 0.055 13.1 2.3 0.058 13.0 1.6 1.0 1 0 0 1 1 1 0 SeqA protein YqfQ PF14181.1 CDI74445.1 - 0.1 12.6 13.9 0.11 12.5 9.6 1.0 1 0 0 1 1 1 0 YqfQ-like protein Sigma70_ner PF04546.8 CDI74445.1 - 0.41 10.2 20.9 0.44 10.1 14.5 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region DUF1777 PF08648.7 CDI74445.1 - 0.7 9.6 5.8 0.7 9.5 4.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) Zip PF02535.17 CDI74445.1 - 0.8 8.6 5.5 0.78 8.6 3.8 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter DUF913 PF06025.7 CDI74445.1 - 0.82 8.3 4.7 0.79 8.4 3.3 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) FYDLN_acid PF09538.5 CDI74445.1 - 0.97 10.0 17.7 1.2 9.8 12.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) DUF3449 PF11931.3 CDI74445.1 - 1.1 8.7 10.4 1 8.8 7.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3449) G-alpha PF00503.15 CDI74445.1 - 1.1 7.8 5.0 1.1 7.8 3.5 1.0 1 0 0 1 1 1 0 G-protein alpha subunit DUF3530 PF12048.3 CDI74445.1 - 1.5 7.7 8.7 1.7 7.5 6.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) Vfa1 PF08432.5 CDI74445.1 - 1.6 8.7 13.6 1.7 8.6 9.4 1.0 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 SpoIIP PF07454.6 CDI74445.1 - 1.7 7.7 8.9 1.9 7.6 6.2 1.0 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) CKAP2_C PF15297.1 CDI74445.1 - 1.8 7.2 12.6 2 7.1 8.8 1.0 1 0 0 1 1 1 0 Cytoskeleton-associated protein 2 C-terminus TRAP_alpha PF03896.11 CDI74445.1 - 2 7.3 20.5 2.2 7.1 14.2 1.0 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit ATP-synt_E PF05680.7 CDI74445.1 - 2 8.4 11.4 2.4 8.1 7.9 1.1 1 0 0 1 1 1 0 ATP synthase E chain DUF2052 PF09747.4 CDI74445.1 - 2.3 8.0 21.3 2.6 7.9 14.8 1.0 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) ECIST_Cterm PF14784.1 CDI74445.1 - 2.6 7.9 6.1 2.9 7.8 4.2 1.1 1 0 0 1 1 1 0 C-terminal domain of the ECSIT protein DUF3276 PF11680.3 CDI74445.1 - 2.7 7.8 11.7 2.9 7.7 8.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3276) AIF_C PF14721.1 CDI74445.1 - 3.1 8.0 6.3 3.4 7.9 4.3 1.1 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term HNOBA PF07701.9 CDI74445.1 - 3.3 6.8 6.5 3.5 6.7 4.5 1.1 1 0 0 1 1 1 0 Heme NO binding associated DDHD PF02862.12 CDI74445.1 - 3.5 7.3 10.2 3.5 7.3 7.1 1.0 1 0 0 1 1 1 0 DDHD domain SspB PF04386.8 CDI74445.1 - 3.8 7.1 13.2 4.2 6.9 9.2 1.1 1 0 0 1 1 1 0 Stringent starvation protein B NPR3 PF03666.8 CDI74445.1 - 4.2 5.8 5.3 4.5 5.7 3.6 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 CobT PF06213.7 CDI74445.1 - 4.8 6.2 27.0 5.3 6.0 18.7 1.0 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT CENP-T PF15511.1 CDI74445.1 - 4.9 6.2 15.5 5.3 6.1 10.8 1.0 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T DUF694 PF05107.7 CDI74445.1 - 5 6.2 6.3 5.6 6.1 4.4 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF694) SprA-related PF12118.3 CDI74445.1 - 5 6.3 12.4 5.5 6.2 8.6 1.0 1 0 0 1 1 1 0 SprA-related family Usp PF00582.21 CDI74445.1 - 5.1 7.2 10.3 5.6 7.1 7.1 1.1 1 0 0 1 1 1 0 Universal stress protein family HAUS6_N PF14661.1 CDI74445.1 - 5.1 6.3 7.2 5.5 6.2 5.0 1.0 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus DUF3381 PF11861.3 CDI74445.1 - 5.3 6.5 24.0 6.5 6.2 16.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) Paf1 PF03985.8 CDI74445.1 - 5.3 5.6 28.0 5.9 5.5 19.4 1.0 1 0 0 1 1 1 0 Paf1 Afi1 PF07792.7 CDI74445.1 - 5.7 6.9 8.9 6.6 6.7 6.2 1.1 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking WBS_methylT PF12589.3 CDI74445.1 - 6 7.4 7.9 8.1 7.0 5.5 1.3 1 0 0 1 1 1 0 Methyltransferase involved in Williams-Beuren syndrome RR_TM4-6 PF06459.7 CDI74445.1 - 7.2 6.4 16.9 7.8 6.3 11.7 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF1510 PF07423.6 CDI74445.1 - 7.4 5.8 23.0 8.5 5.6 16.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) CDC45 PF02724.9 CDI74445.1 - 7.5 4.4 20.0 7.7 4.4 13.9 1.0 1 0 0 1 1 1 0 CDC45-like protein Tim54 PF11711.3 CDI74445.1 - 9.1 4.7 14.5 10 4.5 10.0 1.0 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 PRP21_like_P PF12230.3 CDI74445.1 - 9.4 5.6 15.8 11 5.4 11.0 1.1 1 0 0 1 1 1 0 Pre-mRNA splicing factor PRP21 like protein TraH_2 PF06871.6 CDI74445.1 - 9.4 5.6 7.1 9.9 5.5 4.9 1.1 1 0 0 1 1 1 0 TraH_2 Rtf2 PF04641.7 CDI74447.1 - 0.15 11.2 21.8 0.16 11.1 15.1 1.0 1 0 0 1 1 1 0 Rtf2 RING-finger DUF1510 PF07423.6 CDI74447.1 - 0.31 10.3 20.8 0.33 10.2 14.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DUF2052 PF09747.4 CDI74447.1 - 2.4 8.0 28.0 2.8 7.8 19.4 1.0 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) CDC45 PF02724.9 CDI74447.1 - 2.6 5.9 21.2 2.6 5.9 14.7 1.0 1 0 0 1 1 1 0 CDC45-like protein IncA PF04156.9 CDI74448.1 - 0.00041 19.9 3.6 0.00041 19.9 2.5 1.7 2 0 0 2 2 2 1 IncA protein Med15 PF09606.5 CDI74448.1 - 0.12 10.5 23.2 0.14 10.3 16.1 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal TFIIA PF03153.8 CDI74448.1 - 0.33 10.8 20.5 0.39 10.5 14.2 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Mnd1 PF03962.10 CDI74450.1 - 0.01 15.5 5.5 0.01 15.5 3.8 3.1 2 1 1 3 3 3 0 Mnd1 family Ribosomal_60s PF00428.14 CDI74450.1 - 1.7 9.0 22.7 1.1 9.7 2.6 2.7 3 0 0 3 3 3 0 60s Acidic ribosomal protein Neur_chan_memb PF02932.11 CDI74450.1 - 3.3 7.5 29.9 0.3 10.9 14.6 2.5 2 1 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region N6_N4_Mtase PF01555.13 CDI74451.1 - 0.0015 18.0 0.0 0.11 11.9 0.0 2.8 1 1 0 1 1 1 1 DNA methylase Claudin_2 PF13903.1 CDI74451.1 - 0.0063 16.2 6.2 0.0063 16.2 4.3 5.3 3 1 0 3 3 3 1 PMP-22/EMP/MP20/Claudin tight junction Patatin PF01734.17 CDI74451.1 - 0.0072 16.2 0.6 16 5.3 3.7 2.4 2 1 0 2 2 2 1 Patatin-like phospholipase Ycf1 PF05758.7 CDI74451.1 - 0.38 8.4 38.6 0.23 9.1 22.3 2.2 2 0 0 2 2 2 0 Ycf1 Hid1 PF12722.2 CDI74451.1 - 0.71 7.4 45.4 0.52 7.9 24.5 2.1 2 0 0 2 2 2 0 High-temperature-induced dauer-formation protein Parvo_coat PF00740.13 CDI74451.1 - 1.3 7.9 45.0 0.16 10.8 20.3 2.3 2 0 0 2 2 2 0 Parvovirus coat protein VP2 Hist_deacetyl PF00850.14 CDI74451.1 - 3.5 6.8 24.8 1.2 8.3 2.5 2.4 2 0 0 2 2 2 0 Histone deacetylase domain DUF3357 PF11837.3 CDI74454.1 - 1.4 8.8 15.7 9.3 6.1 5.7 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF3357) TFIIA PF03153.8 CDI74454.1 - 3.3 7.4 57.1 5.3 6.8 39.6 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit FAM60A PF15396.1 CDI74454.1 - 5 6.7 22.3 6.1 6.5 4.8 2.2 2 0 0 2 2 2 0 Protein Family FAM60A FATC PF02260.15 CDI74455.1 - 2.5e-12 46.0 0.0 5.8e-12 44.8 0.0 1.7 1 0 0 1 1 1 1 FATC domain FA_desaturase PF00487.19 CDI74455.1 - 3 7.2 8.0 4.3 6.7 2.9 3.1 3 0 0 3 3 3 0 Fatty acid desaturase Cytochrom_C_asm PF01578.15 CDI74456.1 - 2.3 7.7 1.6 13 5.2 1.1 2.5 1 0 0 1 1 1 0 Cytochrome C assembly protein FBPase PF00316.15 CDI74457.1 - 2e-56 191.2 0.4 1.6e-38 132.3 0.2 2.0 1 1 1 2 2 2 2 Fructose-1-6-bisphosphatase zf-CCHC PF00098.18 CDI74458.1 - 1.3e-06 28.0 7.8 0.0067 16.3 0.3 2.6 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_4 PF14392.1 CDI74458.1 - 0.0002 20.9 2.6 0.26 10.9 0.3 2.7 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_6 PF15288.1 CDI74458.1 - 0.0002 20.9 3.1 0.012 15.2 0.1 2.9 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_2 PF13696.1 CDI74458.1 - 0.23 11.0 3.9 1.7 8.1 0.8 2.4 1 1 1 2 2 2 0 Zinc knuckle zf-CCHC_3 PF13917.1 CDI74458.1 - 0.32 10.7 10.6 1 9.1 0.3 3.7 2 1 1 3 3 3 0 Zinc knuckle DUF3112 PF11309.3 CDI74459.1 - 0.87 9.3 3.9 11 5.8 2.7 2.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3112) DUF4045 PF13254.1 CDI74460.1 - 0.11 11.8 23.4 0.11 11.7 16.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) CDC45 PF02724.9 CDI74460.1 - 0.25 9.3 23.0 0.26 9.2 15.9 1.0 1 0 0 1 1 1 0 CDC45-like protein DUF4175 PF13779.1 CDI74460.1 - 0.65 7.6 71.4 0.73 7.4 49.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) AAA_11 PF13086.1 CDI74460.1 - 0.65 9.5 23.0 0.73 9.3 15.9 1.1 1 0 0 1 1 1 0 AAA domain Bul1_N PF04425.7 CDI74460.1 - 1.2 7.6 20.7 1.1 7.7 14.4 1.0 1 0 0 1 1 1 0 Bul1 N terminus Vfa1 PF08432.5 CDI74460.1 - 1.2 9.0 26.8 1.5 8.8 18.6 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Utp14 PF04615.8 CDI74460.1 - 1.4 7.0 32.4 1.6 6.8 22.5 1.0 1 0 0 1 1 1 0 Utp14 protein Cellulose_synt PF03552.9 CDI74460.1 - 1.7 6.8 11.7 1.7 6.8 8.1 1.0 1 0 0 1 1 1 0 Cellulose synthase Herpes_env PF01673.13 CDI74460.1 - 1.8 7.0 19.3 1.8 7.0 13.4 1.0 1 0 0 1 1 1 0 Herpesvirus putative major envelope glycoprotein PLRV_ORF5 PF01690.12 CDI74460.1 - 1.8 7.6 25.4 1.9 7.5 17.6 1.0 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein DUF966 PF06136.8 CDI74460.1 - 1.9 7.8 27.2 2.2 7.6 18.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Spore_coat_CotO PF14153.1 CDI74460.1 - 1.9 7.8 38.0 2.2 7.6 26.3 1.1 1 0 0 1 1 1 0 Spore coat protein CotO Hid1 PF12722.2 CDI74460.1 - 1.9 6.0 29.5 1.9 6.0 20.5 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein NARP1 PF12569.3 CDI74460.1 - 2 7.0 27.0 2.5 6.7 18.7 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 GAGA_bind PF06217.7 CDI74460.1 - 2.1 8.2 26.0 2.3 8.0 18.0 1.0 1 0 0 1 1 1 0 GAGA binding protein-like family Peptidase_S64 PF08192.6 CDI74460.1 - 2.1 6.5 19.9 2.5 6.3 13.8 1.1 1 0 0 1 1 1 0 Peptidase family S64 DUF2126 PF09899.4 CDI74460.1 - 2.3 6.1 19.8 2.5 6.0 13.7 1.1 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) Neur_chan_memb PF02932.11 CDI74460.1 - 3 7.6 21.7 3.3 7.5 15.0 1.0 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF572 PF04502.8 CDI74460.1 - 3.3 6.8 26.9 3.8 6.6 18.7 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF572) PAT1 PF09770.4 CDI74460.1 - 3.6 5.6 68.3 4 5.5 47.4 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SAPS PF04499.10 CDI74460.1 - 3.7 6.0 25.9 4 5.9 17.9 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF506 PF04720.7 CDI74460.1 - 3.7 7.1 13.5 4.1 6.9 9.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF506) Miff PF05644.6 CDI74460.1 - 3.8 7.0 19.0 4.6 6.8 13.2 1.1 1 0 0 1 1 1 0 Mitochondrial and peroxisomal fission factor Mff DUF4207 PF13904.1 CDI74460.1 - 4.2 6.6 51.9 5.2 6.3 36.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4207) Ycf1 PF05758.7 CDI74460.1 - 4.6 4.8 28.1 4.9 4.7 19.5 1.0 1 0 0 1 1 1 0 Ycf1 Hom_end_hint PF05203.11 CDI74460.1 - 4.8 6.8 19.5 6.2 6.4 13.5 1.2 1 0 0 1 1 1 0 Hom_end-associated Hint TT_ORF1 PF02956.9 CDI74460.1 - 4.8 5.5 22.2 5.3 5.3 15.4 1.1 1 0 0 1 1 1 0 TT viral orf 1 AUX_IAA PF02309.11 CDI74460.1 - 5 6.8 24.5 7.1 6.3 17.0 1.3 1 0 0 1 1 1 0 AUX/IAA family ARD PF03079.9 CDI74460.1 - 5.6 6.8 12.8 6.8 6.6 8.8 1.2 1 0 0 1 1 1 0 ARD/ARD' family PIH1 PF08190.7 CDI74460.1 - 6.5 6.1 36.2 8.3 5.7 25.1 1.2 1 0 0 1 1 1 0 pre-RNA processing PIH1/Nop17 DUF2201_N PF13203.1 CDI74460.1 - 6.8 5.7 32.8 7.6 5.6 22.8 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain Zip PF02535.17 CDI74460.1 - 6.8 5.5 15.6 7.5 5.4 10.8 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter VID27 PF08553.5 CDI74460.1 - 7.3 4.6 23.3 8.4 4.4 16.2 1.0 1 0 0 1 1 1 0 VID27 cytoplasmic protein SPX PF03105.14 CDI74460.1 - 7.5 6.2 26.2 8.7 6.0 18.2 1.1 1 0 0 1 1 1 0 SPX domain DUF2828 PF11443.3 CDI74460.1 - 7.7 4.5 20.2 8.4 4.4 14.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) DUF1510 PF07423.6 CDI74460.1 - 8 5.7 33.7 9.7 5.4 23.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) F-protein PF00469.15 CDI74460.1 - 8.4 5.6 22.4 10 5.3 15.5 1.2 1 0 0 1 1 1 0 Negative factor, (F-Protein) or Nef Paramyxo_ncap PF00973.14 CDI74460.1 - 8.4 4.9 24.3 9.3 4.8 16.8 1.0 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Tim54 PF11711.3 CDI74460.1 - 9 4.7 22.5 11 4.4 15.6 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 HSP70 PF00012.15 CDI74460.1 - 9 4.0 21.8 9.8 3.9 15.1 1.0 1 0 0 1 1 1 0 Hsp70 protein Presenilin PF01080.12 CDI74460.1 - 9.4 4.9 19.1 10 4.8 13.2 1.0 1 0 0 1 1 1 0 Presenilin SMN PF06003.7 CDI74460.1 - 9.5 5.2 9.2 13 4.7 6.4 1.3 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) DUF912 PF06024.7 CDI74461.1 - 0.004 17.1 2.1 0.0045 16.9 1.5 1.1 1 0 0 1 1 1 1 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF2201_N PF13203.1 CDI74461.1 - 0.15 11.2 11.6 0.18 10.9 8.0 1.0 1 0 0 1 1 1 0 Putative metallopeptidase domain Otopetrin PF03189.8 CDI74461.1 - 0.16 10.9 10.1 0.17 10.8 7.0 1.0 1 0 0 1 1 1 0 Otopetrin CagX PF03524.10 CDI74461.1 - 0.26 10.5 5.2 0.29 10.3 3.6 1.0 1 0 0 1 1 1 0 Conjugal transfer protein BRF1 PF07741.8 CDI74461.1 - 0.29 11.3 4.3 0.35 11.1 3.0 1.3 1 0 0 1 1 1 0 Brf1-like TBP-binding domain Zip PF02535.17 CDI74461.1 - 0.32 9.9 15.4 0.29 10.0 10.7 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter Pex14_N PF04695.8 CDI74461.1 - 0.39 10.7 13.5 0.39 10.7 9.4 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Peroxin-13_N PF04088.8 CDI74461.1 - 0.4 10.6 3.3 0.41 10.5 2.3 1.1 1 0 0 1 1 1 0 Peroxin 13, N-terminal region RR_TM4-6 PF06459.7 CDI74461.1 - 0.52 10.1 6.3 0.55 10.0 4.4 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Peptidase_S49_N PF08496.5 CDI74461.1 - 0.53 10.0 8.9 0.57 9.9 6.2 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF1764 PF08576.5 CDI74461.1 - 0.64 10.8 7.8 0.71 10.6 5.4 1.1 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) MDFI PF15316.1 CDI74461.1 - 0.79 9.6 8.7 0.8 9.6 6.0 1.0 1 0 0 1 1 1 0 MyoD family inhibitor Herpes_UL4 PF03277.8 CDI74461.1 - 0.82 8.8 8.3 0.95 8.6 5.8 1.0 1 0 0 1 1 1 0 Herpesvirus UL4 family HD-ZIP_N PF04618.7 CDI74461.1 - 1.1 9.8 6.5 1.2 9.6 4.5 1.1 1 0 0 1 1 1 0 HD-ZIP protein N terminus SelP_N PF04592.9 CDI74461.1 - 1.2 8.5 23.1 1.3 8.3 16.0 1.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region eIF3_subunit PF08597.5 CDI74461.1 - 1.3 8.4 6.6 1.5 8.3 4.6 1.1 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit RIC3 PF15361.1 CDI74461.1 - 1.6 8.9 10.8 1.7 8.8 7.5 1.1 1 0 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 HGTP_anticodon2 PF12745.2 CDI74461.1 - 1.7 7.7 9.1 1.7 7.6 6.3 1.1 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs AIF_C PF14721.1 CDI74461.1 - 1.8 8.8 7.6 2 8.6 5.2 1.1 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Baculo_PP31 PF05311.6 CDI74461.1 - 1.8 7.7 9.2 1.9 7.6 6.4 1.0 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) Pan_kinase PF03309.9 CDI74461.1 - 1.9 7.9 5.0 2.2 7.7 3.4 1.1 1 0 0 1 1 1 0 Type III pantothenate kinase AUX_IAA PF02309.11 CDI74461.1 - 1.9 8.1 8.0 2.1 8.0 5.6 1.0 1 0 0 1 1 1 0 AUX/IAA family TMEM51 PF15345.1 CDI74461.1 - 2 8.0 11.7 2.1 7.9 8.1 1.1 1 0 0 1 1 1 0 Transmembrane protein 51 Gti1_Pac2 PF09729.4 CDI74461.1 - 2 8.2 7.2 2.2 8.1 5.0 1.1 1 0 0 1 1 1 0 Gti1/Pac2 family DUF3675 PF12428.3 CDI74461.1 - 2 8.6 5.4 2.2 8.5 3.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3675) SprA-related PF12118.3 CDI74461.1 - 2.1 7.5 25.7 2.3 7.4 17.8 1.0 1 0 0 1 1 1 0 SprA-related family DUF3464 PF11947.3 CDI74461.1 - 2.6 7.5 6.3 2.9 7.3 4.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) CRF1 PF10380.4 CDI74461.1 - 3 8.1 6.7 3 8.1 4.7 1.1 1 0 0 1 1 1 0 Transcription factor CRF1 Spore_coat_CotO PF14153.1 CDI74461.1 - 3.2 7.1 15.3 3.4 7.0 10.6 1.1 1 0 0 1 1 1 0 Spore coat protein CotO Kei1 PF08552.6 CDI74461.1 - 3.3 7.3 6.2 3.2 7.3 4.3 1.1 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 Folate_carrier PF01770.13 CDI74461.1 - 4.4 5.7 7.1 4.9 5.5 4.9 1.0 1 0 0 1 1 1 0 Reduced folate carrier Bud13 PF09736.4 CDI74461.1 - 4.4 7.5 13.1 5.2 7.3 9.1 1.1 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex DDRGK PF09756.4 CDI74461.1 - 4.5 6.6 13.3 5.2 6.4 9.2 1.1 1 0 0 1 1 1 0 DDRGK domain Serinc PF03348.10 CDI74461.1 - 4.7 5.8 8.9 5.1 5.6 6.2 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) Endonuc_Holl PF10107.4 CDI74461.1 - 4.8 6.8 9.8 5.5 6.6 6.8 1.1 1 0 0 1 1 1 0 Endonuclease related to archaeal Holliday junction resolvase SeqA PF03925.8 CDI74461.1 - 4.8 6.8 9.7 5.3 6.6 6.7 1.1 1 0 0 1 1 1 0 SeqA protein DUF775 PF05603.7 CDI74461.1 - 5.3 6.5 10.3 6.2 6.2 7.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF775) OATP PF03137.15 CDI74461.1 - 6.8 4.6 10.5 6.7 4.6 7.3 1.0 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family DUF2946 PF11162.3 CDI74461.1 - 7.9 6.7 16.5 11 6.2 11.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2946) Hid1 PF12722.2 CDI74461.1 - 8.3 3.9 10.4 8.2 3.9 7.2 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein EIIBC-GUT_N PF03612.9 CDI74461.1 - 8.6 5.9 8.4 9.4 5.8 5.8 1.1 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Neur_chan_memb PF02932.11 CDI74461.1 - 9.3 6.0 8.7 9.9 5.9 6.0 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region BAF1_ABF1 PF04684.8 CDI74462.1 - 5.9e-05 22.1 24.6 8.4e-05 21.6 17.0 1.2 1 0 0 1 1 1 1 BAF1 / ABF1 chromatin reorganising factor Caldesmon PF02029.10 CDI74462.1 - 0.0091 14.4 17.8 0.01 14.2 12.4 1.0 1 0 0 1 1 1 1 Caldesmon Tim54 PF11711.3 CDI74462.1 - 0.017 13.7 10.7 0.018 13.6 7.4 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Dynamin_N PF00350.18 CDI74462.1 - 0.032 14.0 3.1 0.031 14.0 2.2 1.2 1 0 0 1 1 1 0 Dynamin family VIT1 PF01988.14 CDI74462.1 - 0.039 13.4 7.4 0.049 13.1 5.1 1.1 1 0 0 1 1 1 0 VIT family Plasmodium_Vir PF05795.6 CDI74462.1 - 0.045 12.9 8.9 0.051 12.7 6.2 1.0 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Trypan_PARP PF05887.6 CDI74462.1 - 0.064 13.0 4.9 0.079 12.7 3.4 1.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) PAT1 PF09770.4 CDI74462.1 - 0.097 10.8 24.0 0.1 10.7 16.6 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Sporozoite_P67 PF05642.6 CDI74462.1 - 0.11 10.3 10.0 0.12 10.1 6.9 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Pox_Ag35 PF03286.9 CDI74462.1 - 0.11 12.0 16.8 0.13 11.7 11.6 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DUF2052 PF09747.4 CDI74462.1 - 0.12 12.3 20.1 0.14 12.1 13.9 1.1 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) DUF966 PF06136.8 CDI74462.1 - 0.15 11.4 14.4 0.16 11.3 10.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Cwf_Cwc_15 PF04889.7 CDI74462.1 - 0.24 11.0 21.3 0.3 10.7 14.7 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Na_trans_assoc PF06512.8 CDI74462.1 - 0.3 11.0 12.0 0.34 10.8 8.3 1.1 1 0 0 1 1 1 0 Sodium ion transport-associated CENP-T PF15511.1 CDI74462.1 - 0.31 10.2 19.0 0.38 9.9 13.1 1.0 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T CDC73 PF05179.9 CDI74462.1 - 0.32 10.3 13.5 0.38 10.0 9.3 1.0 1 0 0 1 1 1 0 RNA pol II accessory factor, Cdc73 family HCV_NS5a_C PF12941.2 CDI74462.1 - 0.34 10.4 5.6 0.41 10.1 3.9 1.1 1 0 0 1 1 1 0 HCV NS5a protein C-terminal region Pol_alpha_B_N PF08418.5 CDI74462.1 - 0.37 10.3 14.1 0.44 10.0 9.7 1.0 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal ASFV_J13L PF05568.6 CDI74462.1 - 0.43 10.1 4.9 0.52 9.8 3.4 1.2 1 0 0 1 1 1 0 African swine fever virus J13L protein DUF4175 PF13779.1 CDI74462.1 - 0.5 8.0 34.9 0.57 7.8 24.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Med15 PF09606.5 CDI74462.1 - 0.51 8.4 32.2 0.57 8.3 22.3 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DHHW PF14286.1 CDI74462.1 - 0.54 9.5 11.0 0.54 9.5 7.6 1.1 1 0 0 1 1 1 0 DHHW protein DUF4647 PF15504.1 CDI74462.1 - 0.65 8.7 19.3 0.73 8.6 13.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4647) DUF4045 PF13254.1 CDI74462.1 - 0.66 9.2 17.9 0.77 8.9 12.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) PLRV_ORF5 PF01690.12 CDI74462.1 - 0.72 8.9 15.9 0.84 8.7 11.0 1.0 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein DDRGK PF09756.4 CDI74462.1 - 0.73 9.2 28.8 0.86 8.9 19.9 1.1 1 0 0 1 1 1 0 DDRGK domain Asparaginase_2 PF01112.13 CDI74462.1 - 0.78 8.3 7.6 0.9 8.1 5.2 1.1 1 0 0 1 1 1 0 Asparaginase DUF1510 PF07423.6 CDI74462.1 - 0.8 9.0 23.6 0.96 8.7 16.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) FAM176 PF14851.1 CDI74462.1 - 0.81 9.3 11.0 1 9.0 7.6 1.3 1 0 0 1 1 1 0 FAM176 family DUF702 PF05142.7 CDI74462.1 - 0.84 9.7 13.5 1.1 9.4 9.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF702) DUF572 PF04502.8 CDI74462.1 - 0.9 8.7 21.0 1.1 8.4 14.5 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF572) SAPS PF04499.10 CDI74462.1 - 0.9 8.0 16.0 0.99 7.9 11.1 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF3807 PF12720.2 CDI74462.1 - 0.96 9.5 23.3 1.1 9.3 16.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) BTV_NS2 PF04514.7 CDI74462.1 - 1 8.1 12.6 1.2 7.9 8.7 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 DUF4638 PF15472.1 CDI74462.1 - 1.1 8.8 13.5 1.2 8.7 9.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) Hid1 PF12722.2 CDI74462.1 - 1.1 6.8 18.3 1.2 6.7 12.7 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein NST1 PF13945.1 CDI74462.1 - 1.2 9.2 24.1 1.6 8.7 16.7 1.1 1 0 0 1 1 1 0 Salt tolerance down-regulator Afi1 PF07792.7 CDI74462.1 - 1.2 9.0 18.1 1.6 8.7 12.6 1.1 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking FimP PF09766.4 CDI74462.1 - 1.3 7.9 25.1 1.7 7.6 17.4 1.2 1 0 0 1 1 1 0 Fms-interacting protein TMEM51 PF15345.1 CDI74462.1 - 1.4 8.5 19.1 1.7 8.2 13.3 1.0 1 0 0 1 1 1 0 Transmembrane protein 51 Baculo_PP31 PF05311.6 CDI74462.1 - 1.4 8.1 18.7 1.6 7.9 12.9 1.1 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) CDC45 PF02724.9 CDI74462.1 - 1.5 6.7 15.5 1.6 6.6 10.8 1.0 1 0 0 1 1 1 0 CDC45-like protein FLO_LFY PF01698.11 CDI74462.1 - 1.6 7.5 15.3 1.8 7.3 10.6 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein Band_3_cyto PF07565.8 CDI74462.1 - 1.7 8.0 14.4 2 7.8 10.0 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Bud13 PF09736.4 CDI74462.1 - 1.7 8.8 22.9 2.2 8.5 15.9 1.2 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex DUF2126 PF09899.4 CDI74462.1 - 1.8 6.5 12.1 2 6.3 8.4 1.0 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) Dapper PF15268.1 CDI74462.1 - 1.8 7.2 17.9 2 7.0 12.4 1.0 1 0 0 1 1 1 0 Dapper DUF3449 PF11931.3 CDI74462.1 - 2 7.9 18.0 2.2 7.7 12.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3449) Serinc PF03348.10 CDI74462.1 - 2 7.0 12.9 2.1 6.9 9.0 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) Membralin PF09746.4 CDI74462.1 - 2.2 7.2 7.4 2.4 7.1 5.1 1.0 1 0 0 1 1 1 0 Tumour-associated protein FCP1_C PF09309.5 CDI74462.1 - 2.4 7.3 18.7 3.4 6.8 13.0 1.3 1 0 0 1 1 1 0 FCP1, C-terminal Pex16 PF08610.5 CDI74462.1 - 2.6 6.9 11.7 2.7 6.8 8.1 1.1 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) Raftlin PF15250.1 CDI74462.1 - 2.6 6.4 16.2 3 6.2 11.2 1.0 1 0 0 1 1 1 0 Raftlin Rtf2 PF04641.7 CDI74462.1 - 2.8 7.0 20.4 3.8 6.6 14.1 1.3 1 0 0 1 1 1 0 Rtf2 RING-finger DUF2201_N PF13203.1 CDI74462.1 - 2.9 6.9 21.9 3.5 6.7 15.2 1.0 1 0 0 1 1 1 0 Putative metallopeptidase domain Med19 PF10278.4 CDI74462.1 - 3 7.5 18.4 3.5 7.2 12.8 1.2 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 Ndc1_Nup PF09531.5 CDI74462.1 - 3.1 6.0 14.5 3.6 5.8 10.1 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF2122 PF09895.4 CDI74462.1 - 3.2 8.0 8.8 12 6.2 6.1 2.1 1 1 0 1 1 1 0 RecB-family nuclease (DUF2122) Herpes_env PF01673.13 CDI74462.1 - 3.2 6.1 11.1 3.9 5.9 7.7 1.2 1 0 0 1 1 1 0 Herpesvirus putative major envelope glycoprotein TT_ORF1 PF02956.9 CDI74462.1 - 3.3 6.0 11.3 3.5 5.9 7.8 1.0 1 0 0 1 1 1 0 TT viral orf 1 GAGA_bind PF06217.7 CDI74462.1 - 3.4 7.5 18.2 3.9 7.3 12.6 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family Bap31 PF05529.7 CDI74462.1 - 3.5 7.0 14.9 4.2 6.7 10.3 1.3 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like DDHD PF02862.12 CDI74462.1 - 3.5 7.3 17.3 4.3 7.0 12.0 1.2 1 0 0 1 1 1 0 DDHD domain VID27 PF08553.5 CDI74462.1 - 3.6 5.6 14.0 3.8 5.6 9.7 1.0 1 0 0 1 1 1 0 VID27 cytoplasmic protein Hom_end_hint PF05203.11 CDI74462.1 - 4 7.0 10.9 4.5 6.9 7.6 1.2 1 0 0 1 1 1 0 Hom_end-associated Hint eIF-3_zeta PF05091.7 CDI74462.1 - 4.1 5.9 18.9 4.6 5.7 13.1 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) TFIIA PF03153.8 CDI74462.1 - 4.2 7.1 25.8 5.2 6.8 17.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit EPL1 PF10513.4 CDI74462.1 - 4.4 7.5 19.3 5.6 7.1 13.3 1.1 1 0 0 1 1 1 0 Enhancer of polycomb-like TRAP_alpha PF03896.11 CDI74462.1 - 4.9 6.0 10.3 5.7 5.8 7.1 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Peptidase_S64 PF08192.6 CDI74462.1 - 5.2 5.2 12.8 6.5 4.9 8.9 1.2 1 0 0 1 1 1 0 Peptidase family S64 GPCR_chapero_1 PF11904.3 CDI74462.1 - 5.7 5.9 17.8 6.7 5.7 12.3 1.1 1 0 0 1 1 1 0 GPCR-chaperone Ycf1 PF05758.7 CDI74462.1 - 6.5 4.3 21.8 7.4 4.1 15.1 1.0 1 0 0 1 1 1 0 Ycf1 Neur_chan_memb PF02932.11 CDI74462.1 - 6.9 6.4 14.7 8 6.2 10.2 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Apc1 PF12859.2 CDI74462.1 - 7.7 6.7 7.2 12 6.2 5.0 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 1 Zip PF02535.17 CDI74462.1 - 7.8 5.3 8.8 9.6 5.0 6.1 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Glyco_transf_15 PF01793.11 CDI74462.1 - 8.2 5.2 16.0 9.5 5.0 11.1 1.1 1 0 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase AAA_13 PF13166.1 CDI74462.1 - 8.3 4.7 21.4 9.1 4.5 14.8 1.0 1 0 0 1 1 1 0 AAA domain AUX_IAA PF02309.11 CDI74462.1 - 8.3 6.0 15.2 11 5.7 10.5 1.2 1 0 0 1 1 1 0 AUX/IAA family FAM60A PF15396.1 CDI74462.1 - 8.8 6.0 16.1 11 5.7 11.2 1.1 1 0 0 1 1 1 0 Protein Family FAM60A Paramyxo_ncap PF00973.14 CDI74462.1 - 8.9 4.8 16.4 10 4.7 11.4 1.0 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Mem_trans PF03547.13 CDI74462.1 - 8.9 4.4 9.8 10 4.3 6.8 1.1 1 0 0 1 1 1 0 Membrane transport protein Herpes_DNAp_acc PF04929.7 CDI74462.1 - 8.9 5.1 12.5 9.7 5.0 8.7 1.2 1 0 0 1 1 1 0 Herpes DNA replication accessory factor DUF3260 PF11658.3 CDI74462.1 - 9 4.3 13.0 10 4.1 9.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3260) DUF2828 PF11443.3 CDI74462.1 - 9.6 4.2 14.2 10 4.1 9.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) DUF3347 PF11827.3 CDI74462.1 - 9.8 6.1 22.2 13 5.6 15.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3347) PFK PF00365.15 CDI74463.1 - 7.6e-30 103.8 0.1 8.1e-22 77.4 0.0 3.0 2 0 0 2 2 2 2 Phosphofructokinase DUF4401 PF14351.1 CDI74463.1 - 3 6.7 0.7 7.9 5.3 0.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4401) Hydrolase_3 PF08282.7 CDI74464.1 - 6.9e-43 147.0 0.0 8.8e-43 146.7 0.0 1.0 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.8 CDI74464.1 - 5.1e-06 25.9 0.0 0.00016 21.0 0.0 2.1 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase BAF1_ABF1 PF04684.8 CDI74468.1 - 2.8e-05 23.2 14.4 3.1e-05 23.0 10.0 1.0 1 0 0 1 1 1 1 BAF1 / ABF1 chromatin reorganising factor Ribosomal_60s PF00428.14 CDI74468.1 - 0.00076 19.8 8.5 0.0011 19.3 5.9 1.3 1 0 0 1 1 1 1 60s Acidic ribosomal protein DivIC PF04977.10 CDI74468.1 - 0.0097 15.3 8.2 0.018 14.4 5.7 1.5 1 0 0 1 1 1 1 Septum formation initiator Med15 PF09606.5 CDI74468.1 - 0.011 13.9 18.2 0.015 13.5 12.6 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Pex16 PF08610.5 CDI74468.1 - 0.074 12.0 3.0 0.083 11.8 2.1 1.0 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) Sec62 PF03839.11 CDI74468.1 - 0.15 11.4 1.1 0.16 11.3 0.8 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 PP_kinase_N PF13089.1 CDI74468.1 - 0.15 12.1 0.1 0.15 12.1 0.0 2.1 1 1 1 2 2 2 0 Polyphosphate kinase N-terminal domain LCD1 PF09798.4 CDI74468.1 - 0.68 7.8 8.3 0.75 7.7 5.8 1.1 1 0 0 1 1 1 0 DNA damage checkpoint protein Nitroreductase PF00881.19 CDI74468.1 - 0.79 9.5 6.3 0.98 9.2 4.4 1.2 1 0 0 1 1 1 0 Nitroreductase family CDK2AP PF09806.4 CDI74468.1 - 1.5 9.0 19.5 1.7 8.8 13.5 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein DUF3347 PF11827.3 CDI74468.1 - 1.5 8.7 11.8 1.9 8.4 8.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3347) Hid1 PF12722.2 CDI74468.1 - 2.8 5.4 6.8 3 5.4 4.7 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF788 PF05620.6 CDI74468.1 - 6.8 6.5 7.4 3.1 7.6 2.9 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF788) DUF912 PF06024.7 CDI74468.1 - 8.9 6.4 8.7 25 4.9 6.1 1.8 1 1 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) UPF0016 PF01169.14 CDI74469.1 - 4.2e-20 71.6 2.1 5e-20 71.4 1.5 1.1 1 0 0 1 1 1 1 Uncharacterized protein family UPF0016 B12-binding PF02310.14 CDI74469.1 - 0.025 14.4 0.0 0.028 14.2 0.0 1.1 1 0 0 1 1 1 0 B12 binding domain LysE PF01810.13 CDI74469.1 - 0.043 13.0 2.7 0.049 12.9 1.9 1.0 1 0 0 1 1 1 0 LysE type translocator InaF-motif PF15018.1 CDI74469.1 - 0.33 10.4 0.2 0.33 10.4 0.1 1.6 2 0 0 2 2 2 0 TRP-interacting helix RNase_H2_suC PF08615.6 CDI74470.1 - 4e-10 39.6 0.0 6.8e-10 38.9 0.0 1.4 1 1 0 1 1 1 1 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) FAM117 PF15388.1 CDI74471.1 - 0.023 13.9 1.6 0.026 13.7 1.1 1.0 1 0 0 1 1 1 0 Protein Family FAM117 Peptidase_S24 PF00717.18 CDI74472.1 - 1.4e-07 31.0 0.0 2.2e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 Peptidase S24-like DUF3099 PF11298.3 CDI74472.1 - 3.9 7.2 6.3 2 8.2 0.5 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF3099) Mucin PF01456.12 CDI74478.1 - 0.00029 20.6 4.2 0.00029 20.6 2.9 2.7 1 1 1 2 2 2 1 Mucin-like glycoprotein CDK2AP PF09806.4 CDI74478.1 - 0.0057 16.9 11.2 0.0057 16.9 7.8 3.0 2 1 0 2 2 2 1 Cyclin-dependent kinase 2-associated protein YndJ PF14158.1 CDI74478.1 - 0.72 8.8 9.2 0.054 12.5 2.9 1.6 2 0 0 2 2 2 0 YndJ-like protein SR-25 PF10500.4 CDI74479.1 - 0.0083 15.6 5.6 0.0083 15.6 3.9 8.1 3 2 5 8 8 8 1 Nuclear RNA-splicing-associated protein DUF755 PF05501.6 CDI74479.1 - 0.012 15.6 10.6 0.012 15.6 7.3 8.5 5 4 3 8 8 8 0 Domain of unknown function (DUF755) RskA PF10099.4 CDI74480.1 - 0.0045 16.7 1.6 0.0051 16.5 1.1 1.0 1 0 0 1 1 1 1 Anti-sigma-K factor rskA DUF1049 PF06305.6 CDI74480.1 - 0.066 12.6 1.6 0.069 12.6 0.6 1.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1049) Chordopox_A30L PF06015.7 CDI74480.1 - 0.073 12.6 0.1 0.092 12.3 0.1 1.2 1 0 0 1 1 1 0 Chordopoxvirus A30L protein FimP PF09766.4 CDI74481.1 - 0.0018 17.4 9.8 0.18 10.8 0.5 2.3 2 0 0 2 2 2 2 Fms-interacting protein BAF1_ABF1 PF04684.8 CDI74481.1 - 0.0061 15.4 6.4 0.0061 15.4 4.4 9.7 8 3 0 8 8 8 1 BAF1 / ABF1 chromatin reorganising factor ERF PF04404.7 CDI74481.1 - 0.047 13.2 15.4 0.4 10.1 1.0 2.7 2 0 0 2 2 2 0 ERF superfamily RAB3GAP2_N PF14655.1 CDI74481.1 - 0.11 11.4 12.6 0.72 8.7 1.4 2.4 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Cyclin PF08613.6 CDI74481.1 - 0.92 9.9 6.2 34 4.8 0.0 4.0 3 1 0 3 3 3 0 Cyclin Macoilin PF09726.4 CDI74481.1 - 3.7 5.7 20.6 0.36 9.0 4.3 3.2 3 0 0 3 3 3 0 Transmembrane protein Spore_coat_CotO PF14153.1 CDI74483.1 - 0.48 9.8 33.0 0.55 9.6 22.9 1.1 1 0 0 1 1 1 0 Spore coat protein CotO Cellulose_synt PF03552.9 CDI74483.1 - 1.8 6.7 11.7 2 6.6 8.1 1.0 1 0 0 1 1 1 0 Cellulose synthase DUF2413 PF10310.4 CDI74483.1 - 2.5 6.8 32.2 2.9 6.6 22.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) HCO3_cotransp PF00955.16 CDI74483.1 - 2.6 6.6 9.2 2.8 6.4 6.4 1.0 1 0 0 1 1 1 0 HCO3- transporter family DDRGK PF09756.4 CDI74483.1 - 3.2 7.1 30.7 3.9 6.8 21.3 1.3 1 0 0 1 1 1 0 DDRGK domain CDC45 PF02724.9 CDI74483.1 - 4.4 5.2 23.9 4.3 5.2 16.6 1.1 1 0 0 1 1 1 0 CDC45-like protein NPR3 PF03666.8 CDI74483.1 - 6.3 5.2 24.6 6.4 5.1 17.0 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF4045 PF13254.1 CDI74483.1 - 6.5 5.9 26.5 7.3 5.7 18.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Nucleoside_tran PF01733.13 CDI74483.1 - 6.8 5.7 7.5 10 5.1 5.2 1.4 1 0 0 1 1 1 0 Nucleoside transporter Utp14 PF04615.8 CDI74483.1 - 7.6 4.5 32.0 8.4 4.4 22.2 1.0 1 0 0 1 1 1 0 Utp14 protein Draxin PF15550.1 CDI74483.1 - 9.8 5.7 26.2 12 5.4 18.2 1.1 1 0 0 1 1 1 0 Draxin SNF2_N PF00176.18 CDI74484.1 - 3e-72 242.9 1.9 3e-72 242.9 1.3 4.5 4 1 0 4 4 4 1 SNF2 family N-terminal domain Chromo PF00385.19 CDI74485.1 - 1.2e-09 37.7 0.0 1.7e-09 37.1 0.0 1.3 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-CCHC PF00098.18 CDI74486.1 - 5.3e-06 26.1 7.8 0.013 15.3 1.0 2.2 2 0 0 2 2 2 2 Zinc knuckle DnaJ_CXXCXGXG PF00684.14 CDI74486.1 - 0.024 14.6 1.7 0.042 13.9 1.2 1.4 1 0 0 1 1 1 0 DnaJ central domain zf-CCHC_6 PF15288.1 CDI74486.1 - 0.1 12.2 2.7 3.2 7.5 0.2 2.5 2 0 0 2 2 2 0 Zinc knuckle mRNA_triPase PF02940.10 CDI74490.1 - 1.7e-05 24.6 0.4 0.00067 19.4 0.0 2.3 2 1 0 2 2 2 1 mRNA capping enzyme, beta chain eIF3_subunit PF08597.5 CDI74490.1 - 0.0016 18.0 1.6 0.01 15.4 1.8 1.7 2 0 0 2 2 2 1 Translation initiation factor eIF3 subunit Ycf1 PF05758.7 CDI74490.1 - 0.0033 15.2 0.3 0.0033 15.2 0.2 1.0 1 0 0 1 1 1 1 Ycf1 DUF3371 PF11851.3 CDI74490.1 - 0.0044 17.7 7.6 0.0088 16.7 5.3 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3371) Gti1_Pac2 PF09729.4 CDI74490.1 - 0.005 16.7 0.0 0.005 16.7 0.0 1.1 1 0 0 1 1 1 1 Gti1/Pac2 family LMBR1 PF04791.11 CDI74490.1 - 0.046 12.3 0.0 0.06 11.9 0.0 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Ctr PF04145.10 CDI74490.1 - 0.051 13.6 0.5 0.062 13.3 0.3 1.3 1 0 0 1 1 1 0 Ctr copper transporter family Dynamin_N PF00350.18 CDI74490.1 - 0.054 13.3 0.8 0.067 13.0 0.6 1.2 1 0 0 1 1 1 0 Dynamin family DUF4632 PF15451.1 CDI74490.1 - 0.092 12.6 0.2 0.27 11.1 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4632) Neur_chan_memb PF02932.11 CDI74490.1 - 0.13 12.1 0.2 0.12 12.2 0.1 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF3987 PF13148.1 CDI74490.1 - 0.24 9.9 4.0 0.31 9.5 2.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) PAT1 PF09770.4 CDI74490.1 - 0.61 8.2 28.8 0.89 7.7 20.0 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 CDK5_activator PF03261.10 CDI74490.1 - 1.7 7.8 7.6 2.4 7.4 5.3 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein DDHD PF02862.12 CDI74490.1 - 3.5 7.3 8.8 5.4 6.7 6.1 1.2 1 0 0 1 1 1 0 DDHD domain Band_3_cyto PF07565.8 CDI74490.1 - 5.1 6.5 13.0 7.9 5.9 9.0 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain ATP-synt_E PF05680.7 CDI74490.1 - 5.4 7.0 14.0 12 5.9 9.7 1.6 1 0 0 1 1 1 0 ATP synthase E chain FCP1_C PF09309.5 CDI74490.1 - 5.4 6.2 12.8 12 5.1 8.9 1.6 1 0 0 1 1 1 0 FCP1, C-terminal Kei1 PF08552.6 CDI74490.1 - 5.6 6.5 6.4 8 6.0 4.4 1.1 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 Pex14_N PF04695.8 CDI74490.1 - 9.6 6.2 20.2 15 5.6 14.0 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Peptidase_M22 PF00814.20 CDI74491.1 - 8.2e-22 77.9 7.3 1e-15 57.9 0.0 3.4 4 0 0 4 4 3 2 Glycoprotease family Spt20 PF12090.3 CDI74491.1 - 0.0025 17.2 15.0 0.27 10.5 2.6 3.1 3 0 0 3 3 3 2 Spt20 family FHIPEP PF00771.15 CDI74491.1 - 0.0057 15.0 10.6 0.016 13.5 2.2 2.7 3 0 0 3 3 3 2 FHIPEP family DUF4207 PF13904.1 CDI74491.1 - 0.011 15.1 4.2 0.011 15.1 2.9 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4207) AAA_23 PF13476.1 CDI74491.1 - 0.024 14.9 0.8 0.024 14.9 0.6 2.4 2 1 0 2 2 1 0 AAA domain RAB3GAP2_N PF14655.1 CDI74491.1 - 0.066 12.2 20.9 1.3 7.8 2.1 3.1 3 0 0 3 3 3 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Trs65 PF12735.2 CDI74491.1 - 0.089 12.0 0.2 0.089 12.0 0.1 2.3 3 0 0 3 3 3 0 TRAPP trafficking subunit Trs65 FAM176 PF14851.1 CDI74491.1 - 0.24 11.0 3.9 6.6 6.4 0.2 2.8 3 0 0 3 3 3 0 FAM176 family Ctr PF04145.10 CDI74491.1 - 0.7 9.9 9.6 2.8 8.0 0.4 3.3 3 0 0 3 3 3 0 Ctr copper transporter family DUF2371 PF10177.4 CDI74491.1 - 0.76 9.6 3.3 1.6 8.5 0.3 2.3 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2371) DUF3371 PF11851.3 CDI74491.1 - 0.88 10.2 24.2 0.45 11.1 2.3 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF3371) AUX_IAA PF02309.11 CDI74491.1 - 0.92 9.2 8.9 3 7.5 0.6 2.8 3 0 0 3 3 3 0 AUX/IAA family PAT1 PF09770.4 CDI74491.1 - 1.1 7.4 39.3 0.96 7.6 6.2 2.1 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 DUF607 PF04678.8 CDI74491.1 - 1.6 8.5 10.8 2.5 7.9 1.9 3.1 3 0 0 3 3 3 0 Protein of unknown function, DUF607 DUF3464 PF11947.3 CDI74491.1 - 1.7 8.1 12.5 0.21 11.0 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3464) DUF3801 PF12687.2 CDI74491.1 - 1.8 8.1 20.5 0.05 13.1 2.7 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3801) DUF2722 PF10846.3 CDI74491.1 - 2.4 7.0 27.6 0.1 11.5 0.6 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2722) PH_4 PF15404.1 CDI74491.1 - 3.4 7.1 13.6 5.5 6.4 1.4 3.4 4 0 0 4 4 4 0 Pleckstrin homology domain APC_CDC26 PF10471.4 CDI74491.1 - 4 8.2 40.9 3.7 8.3 7.2 3.4 3 0 0 3 3 3 0 Anaphase-promoting complex APC subunit 1 Consortin_C PF15281.1 CDI74491.1 - 4.5 6.8 7.9 1 8.9 1.0 2.7 3 0 0 3 3 3 0 Consortin C-terminus Glt_symporter PF03616.9 CDI74491.1 - 6.2 5.2 9.4 1.8 6.9 2.4 2.1 2 0 0 2 2 2 0 Sodium/glutamate symporter FPN1 PF06963.7 CDI74491.1 - 6.9 4.9 7.7 11 4.2 0.4 2.3 2 0 0 2 2 2 0 Ferroportin1 (FPN1) FimP PF09766.4 CDI74491.1 - 7.6 5.4 29.6 0.73 8.8 5.2 3.0 3 0 0 3 3 3 0 Fms-interacting protein Pap_E4 PF02711.9 CDI74491.1 - 8.2 7.3 10.3 9.7 7.0 1.3 3.3 3 0 0 3 3 3 0 E4 protein PEX11 PF05648.9 CDI74491.1 - 8.8 5.5 12.1 1.1 8.4 0.1 3.0 3 0 0 3 3 3 0 Peroxisomal biogenesis factor 11 (PEX11) PIG-U PF06728.8 CDI74493.1 - 1.8e-15 56.7 8.5 3.2e-11 42.7 0.2 2.8 2 1 0 2 2 2 2 GPI transamidase subunit PIG-U RR_TM4-6 PF06459.7 CDI74493.1 - 0.0013 18.6 29.8 0.071 12.9 13.7 2.5 3 0 0 3 3 3 2 Ryanodine Receptor TM 4-6 FimP PF09766.4 CDI74493.1 - 0.0096 15.0 11.4 0.0096 15.0 7.9 3.7 3 1 1 4 4 3 1 Fms-interacting protein Cytochrom_B_N_2 PF13631.1 CDI74493.1 - 0.011 15.5 0.0 7.4 6.3 0.0 3.1 4 0 0 4 4 4 0 Cytochrome b(N-terminal)/b6/petB DUF1980 PF09323.5 CDI74493.1 - 0.022 14.4 1.6 0.022 14.4 1.1 4.1 3 1 1 4 4 2 0 Domain of unknown function (DUF1980) DUF3801 PF12687.2 CDI74493.1 - 0.024 14.2 1.0 0.024 14.2 0.7 3.4 3 1 0 3 3 2 0 Protein of unknown function (DUF3801) DUF1510 PF07423.6 CDI74493.1 - 0.22 10.8 50.8 0.12 11.7 2.3 3.5 3 1 1 4 4 4 0 Protein of unknown function (DUF1510) DUF3357 PF11837.3 CDI74493.1 - 0.28 11.0 35.8 0.18 11.6 0.1 5.0 2 2 2 4 4 3 0 Domain of unknown function (DUF3357) OPT PF03169.10 CDI74493.1 - 1.3 7.3 5.7 69 1.6 3.9 2.5 1 1 0 1 1 1 0 OPT oligopeptide transporter protein DUF4366 PF14283.1 CDI74493.1 - 2.2 7.6 25.4 22 4.3 7.9 3.5 2 1 1 3 3 2 0 Domain of unknown function (DUF4366) Utp14 PF04615.8 CDI74493.1 - 5.8 4.9 47.3 1.5 6.8 30.4 1.6 2 0 0 2 2 2 0 Utp14 protein FLO_LFY PF01698.11 CDI74493.1 - 8.1 5.1 37.2 1.4 7.6 2.3 2.3 2 0 0 2 2 2 0 Floricaula / Leafy protein SprA-related PF12118.3 CDI74494.1 - 0.0011 18.3 36.7 0.0014 17.9 25.4 1.1 1 0 0 1 1 1 1 SprA-related family Med15 PF09606.5 CDI74494.1 - 0.0084 14.3 41.1 0.0095 14.2 28.5 1.0 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal AAA_23 PF13476.1 CDI74494.1 - 0.024 14.9 3.2 0.027 14.8 2.2 1.2 1 0 0 1 1 1 0 AAA domain TMEM247 PF15444.1 CDI74494.1 - 0.026 14.3 5.4 0.031 14.0 3.8 1.2 1 0 0 1 1 1 0 Transmembrane protein 247 HemX PF04375.9 CDI74494.1 - 0.043 12.4 26.9 0.062 11.8 18.6 1.3 1 0 0 1 1 1 0 HemX Peptidase_M17_N PF02789.12 CDI74494.1 - 0.085 12.6 6.1 0.12 12.1 4.2 1.3 1 0 0 1 1 1 0 Cytosol aminopeptidase family, N-terminal domain TFIIA PF03153.8 CDI74494.1 - 0.26 11.1 33.8 0.31 10.9 23.4 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit BTV_NS2 PF04514.7 CDI74494.1 - 0.67 8.7 7.5 0.8 8.5 5.2 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 SOBP PF15279.1 CDI74494.1 - 0.76 10.0 15.8 0.93 9.8 10.9 1.0 1 0 0 1 1 1 0 Sine oculis-binding protein RAP1 PF07218.6 CDI74494.1 - 0.82 7.6 7.8 0.97 7.4 5.4 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) PAT1 PF09770.4 CDI74494.1 - 1.5 6.9 29.5 1.6 6.8 20.5 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 CAF-1_p150 PF11600.3 CDI74494.1 - 1.6 8.1 22.1 2.5 7.4 15.3 1.3 1 1 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF3337 PF11816.3 CDI74494.1 - 2.5 7.3 10.8 3.1 7.1 7.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3337) Herpes_UL87 PF03043.9 CDI74494.1 - 3.4 5.9 9.5 3.8 5.7 6.6 1.0 1 0 0 1 1 1 0 Herpesvirus UL87 family DUF966 PF06136.8 CDI74494.1 - 6 6.1 19.6 8.4 5.7 13.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Draxin PF15550.1 CDI74494.1 - 7.2 6.1 11.7 8.8 5.8 8.1 1.2 1 0 0 1 1 1 0 Draxin Bac_luciferase PF00296.15 CDI74496.1 - 0.098 11.7 6.1 0.28 10.2 4.2 1.6 1 1 0 1 1 1 0 Luciferase-like monooxygenase Zip PF02535.17 CDI74496.1 - 0.18 10.7 10.0 0.21 10.5 6.9 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter DUF2052 PF09747.4 CDI74496.1 - 0.26 11.1 29.5 0.3 10.9 20.4 1.0 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) Lin-8 PF03353.10 CDI74496.1 - 0.33 10.2 23.5 0.34 10.1 16.3 1.0 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist SelP_N PF04592.9 CDI74496.1 - 0.52 9.6 21.4 0.56 9.5 14.8 1.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Med19 PF10278.4 CDI74496.1 - 0.82 9.3 14.5 0.85 9.2 10.1 1.1 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 DUF4448 PF14610.1 CDI74496.1 - 1.6 8.2 8.4 2 7.8 5.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) PAT1 PF09770.4 CDI74496.1 - 1.6 6.8 50.5 1.7 6.7 35.0 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SMN PF06003.7 CDI74496.1 - 2.1 7.3 10.5 2.4 7.2 7.3 1.0 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) PCEMA1 PF07418.6 CDI74496.1 - 2.5 7.3 15.3 2.8 7.2 10.6 1.1 1 0 0 1 1 1 0 Acidic phosphoprotein precursor PCEMA1 DUF3474 PF11960.3 CDI74496.1 - 4.1 7.4 5.7 5.8 6.9 4.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3474) CDC45 PF02724.9 CDI74496.1 - 5.3 4.9 22.1 6 4.7 15.3 1.0 1 0 0 1 1 1 0 CDC45-like protein BPL_N PF09825.4 CDI74496.1 - 5.7 5.6 12.8 5.8 5.5 8.8 1.0 1 0 0 1 1 1 0 Biotin-protein ligase, N terminal AAA_11 PF13086.1 CDI74496.1 - 7.8 5.9 20.3 8.1 5.9 14.1 1.1 1 0 0 1 1 1 0 AAA domain PAT1 PF09770.4 CDI74498.1 - 0.0064 14.8 57.8 0.008 14.4 40.0 1.3 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 DUF1675 PF07897.6 CDI74498.1 - 0.13 12.1 25.2 0.077 12.8 15.8 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1675) LMBR1 PF04791.11 CDI74499.1 - 8.8 4.7 7.2 16 3.9 5.0 1.4 1 0 0 1 1 1 0 LMBR1-like membrane protein TFIIA PF03153.8 CDI74500.1 - 0.86 9.4 9.4 0.97 9.2 6.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Med15 PF09606.5 CDI74500.1 - 1.6 6.8 15.4 1.8 6.6 10.7 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal R_equi_Vir PF05526.6 CDI74500.1 - 5.3 6.6 6.4 7.7 6.1 4.4 1.2 1 0 0 1 1 1 0 Rhodococcus equi virulence-associated protein RNA_pol_Rpb2_6 PF00562.23 CDI74501.1 - 4.6e-17 61.8 2.5 2.8e-10 39.4 0.0 2.2 1 1 1 2 2 2 2 RNA polymerase Rpb2, domain 6 RAP1 PF07218.6 CDI74501.1 - 0.0017 16.5 9.8 0.0019 16.4 6.8 1.1 1 0 0 1 1 1 1 Rhoptry-associated protein 1 (RAP-1) Med3 PF11593.3 CDI74501.1 - 0.003 16.8 13.4 0.003 16.8 9.3 2.2 2 0 0 2 2 2 1 Mediator complex subunit 3 fungal SprA-related PF12118.3 CDI74501.1 - 0.014 14.6 25.2 0.019 14.3 17.4 1.1 1 0 0 1 1 1 0 SprA-related family Med15 PF09606.5 CDI74501.1 - 0.022 13.0 20.9 0.025 12.7 14.5 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal FimP PF09766.4 CDI74501.1 - 0.084 11.9 12.0 0.13 11.3 8.4 1.2 1 0 0 1 1 1 0 Fms-interacting protein RAB3GAP2_N PF14655.1 CDI74501.1 - 0.16 10.9 7.5 0.22 10.4 5.2 1.2 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus DivIC PF04977.10 CDI74501.1 - 0.26 10.7 10.7 0.41 10.1 6.7 1.7 2 0 0 2 2 2 0 Septum formation initiator Sulfotransfer_2 PF03567.9 CDI74501.1 - 0.5 10.0 5.7 0.42 10.2 3.1 1.4 1 1 0 1 1 1 0 Sulfotransferase family TCP PF03634.8 CDI74501.1 - 1.5 9.1 18.5 0.93 9.8 4.4 2.1 2 0 0 2 2 2 0 TCP family transcription factor SOBP PF15279.1 CDI74501.1 - 1.7 8.9 11.0 2.3 8.5 7.6 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein AIF_C PF14721.1 CDI74501.1 - 1.9 8.7 7.3 4.7 7.4 2.3 2.1 2 0 0 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term DUF1764 PF08576.5 CDI74501.1 - 2.1 9.1 9.6 1.2 9.9 3.8 2.1 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF1764) RIC3 PF15361.1 CDI74501.1 - 2.1 8.5 11.7 3.4 7.8 2.8 2.1 2 0 0 2 2 2 0 Resistance to inhibitors of cholinesterase homologue 3 Afi1 PF07792.7 CDI74501.1 - 2.2 8.2 10.1 1.1 9.2 3.5 2.1 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking SSP160 PF06933.6 CDI74501.1 - 2.4 6.0 16.3 2.8 5.8 11.3 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 TFIIA PF03153.8 CDI74501.1 - 3.2 7.5 18.9 4.6 7.0 13.1 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit tRNA_synt_1c_R2 PF04557.10 CDI74501.1 - 4.9 7.9 8.1 0.34 11.6 1.4 2.1 2 1 0 2 2 2 0 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 Ashwin PF15323.1 CDI74501.1 - 6.5 6.6 19.4 43 4.0 13.5 2.0 1 1 0 1 1 1 0 Developmental protein DUF4175 PF13779.1 CDI74501.1 - 9.3 3.8 21.7 12 3.4 15.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) MRI PF15325.1 CDI74501.1 - 9.4 7.2 10.5 12 6.9 2.3 2.3 2 0 0 2 2 2 0 Modulator of retrovirus infection DUF1759 PF03564.10 CDI74502.1 - 0.073 12.8 2.2 0.12 12.1 1.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1759) SelP_N PF04592.9 CDI74503.1 - 0.088 12.1 11.1 0.13 11.5 7.7 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Hid1 PF12722.2 CDI74503.1 - 0.12 10.0 1.4 0.13 9.9 1.0 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein UPF0560 PF10577.4 CDI74503.1 - 0.19 9.9 13.0 0.26 9.4 9.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Suf PF05843.9 CDI74503.1 - 0.4 10.3 6.8 0.63 9.7 4.7 1.4 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF3464 PF11947.3 CDI74503.1 - 1.8 7.9 10.1 0.083 12.3 2.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3464) REC114-like PF15165.1 CDI74503.1 - 4.5 6.9 11.8 8.4 6.0 8.2 1.5 1 0 0 1 1 1 0 Meiotic recombination protein REC114-like Ribosomal_60s PF00428.14 CDI74504.1 - 0.0096 16.2 8.7 0.021 15.2 6.0 1.6 1 0 0 1 1 1 1 60s Acidic ribosomal protein IncA PF04156.9 CDI74505.1 - 4.1e-05 23.2 1.7 4.1e-05 23.2 1.2 3.3 2 1 1 3 3 3 1 IncA protein HemX PF04375.9 CDI74505.1 - 0.0053 15.3 15.0 0.0053 15.3 10.4 3.9 2 1 1 4 4 4 1 HemX DUF4366 PF14283.1 CDI74505.1 - 0.0056 16.1 0.4 0.0056 16.1 0.3 2.0 3 0 0 3 3 3 1 Domain of unknown function (DUF4366) Suf PF05843.9 CDI74505.1 - 0.19 11.4 7.1 0.23 11.1 4.9 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DivIC PF04977.10 CDI74505.1 - 6.5 6.3 14.8 3.5 7.1 9.0 1.4 2 0 0 2 2 2 0 Septum formation initiator Sporozoite_P67 PF05642.6 CDI74507.1 - 4.1e-06 24.9 4.1 4.1e-06 24.9 2.9 1.8 1 1 1 2 2 2 1 Sporozoite P67 surface antigen Spore_coat_CotO PF14153.1 CDI74508.1 - 0.00036 20.0 20.2 0.00055 19.4 14.0 1.5 1 0 0 1 1 1 1 Spore coat protein CotO SAPS PF04499.10 CDI74508.1 - 0.0029 16.3 11.9 0.0029 16.3 8.2 1.1 1 0 0 1 1 1 1 SIT4 phosphatase-associated protein DUF4045 PF13254.1 CDI74508.1 - 0.0052 16.1 12.0 0.0057 16.0 8.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4045) LMBR1 PF04791.11 CDI74508.1 - 0.0053 15.4 6.1 0.0059 15.2 4.2 1.1 1 0 0 1 1 1 1 LMBR1-like membrane protein PIG-U PF06728.8 CDI74508.1 - 0.014 14.3 0.7 0.023 13.5 0.5 1.5 1 0 0 1 1 1 0 GPI transamidase subunit PIG-U CRT10 PF08728.5 CDI74508.1 - 0.12 10.3 10.2 0.13 10.2 7.1 1.0 1 0 0 1 1 1 0 CRT10 Lin-8 PF03353.10 CDI74508.1 - 0.19 10.9 20.5 0.24 10.6 14.2 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Presenilin PF01080.12 CDI74508.1 - 0.29 9.9 16.1 0.0049 15.7 6.3 1.6 1 1 1 2 2 2 0 Presenilin Plasmodium_Vir PF05795.6 CDI74508.1 - 0.36 9.9 8.9 1.2 8.2 6.2 1.7 1 1 0 1 1 1 0 Plasmodium vivax Vir protein Cellulose_synt PF03552.9 CDI74508.1 - 1 7.5 4.5 1.3 7.2 3.1 1.3 1 0 0 1 1 1 0 Cellulose synthase Ndc1_Nup PF09531.5 CDI74508.1 - 1.1 7.6 13.2 1.2 7.4 9.1 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Raftlin PF15250.1 CDI74508.1 - 1.4 7.3 23.1 1.9 6.9 16.0 1.1 1 0 0 1 1 1 0 Raftlin Sec62 PF03839.11 CDI74508.1 - 4.8 6.5 17.0 6.9 6.0 11.8 1.4 1 0 0 1 1 1 0 Translocation protein Sec62 V_ATPase_I PF01496.14 CDI74509.1 - 0.06 11.1 0.6 0.85 7.3 0.8 2.0 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family DUF4113 PF13438.1 CDI74509.1 - 0.12 11.9 0.0 0.35 10.4 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4113) Herpes_LMP2 PF07415.6 CDI74511.1 - 2.7 6.5 6.3 4.1 5.8 4.4 1.4 1 0 0 1 1 1 0 Gammaherpesvirus latent membrane protein (LMP2) protein Med15 PF09606.5 CDI74512.1 - 0.00033 19.0 103.4 0.0004 18.7 71.6 1.0 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal CAF-1_p150 PF11600.3 CDI74512.1 - 0.0019 17.6 43.6 0.0024 17.3 30.2 1.1 1 0 0 1 1 1 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal SAGA-Tad1 PF12767.2 CDI74512.1 - 0.094 12.3 39.6 0.11 12.1 27.5 1.1 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit TFIIA PF03153.8 CDI74512.1 - 0.63 9.8 69.2 0.95 9.2 47.9 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PAT1 PF09770.4 CDI74512.1 - 1.7 6.8 85.8 1.9 6.6 59.4 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DNA_pol_viral_N PF00242.12 CDI74512.1 - 1.7 7.5 32.4 1.8 7.4 22.4 1.1 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain DUF4045 PF13254.1 CDI74512.1 - 2 7.6 36.5 2.5 7.2 25.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Caldesmon PF02029.10 CDI74512.1 - 2.3 6.5 33.5 2.8 6.2 23.3 1.2 1 0 0 1 1 1 0 Caldesmon Draxin PF15550.1 CDI74512.1 - 2.6 7.6 32.1 3.3 7.3 22.2 1.2 1 0 0 1 1 1 0 Draxin CDC27 PF09507.5 CDI74512.1 - 2.9 6.9 45.5 3.5 6.7 31.5 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Utp14 PF04615.8 CDI74512.1 - 4.2 5.4 45.7 4.8 5.2 31.7 1.0 1 0 0 1 1 1 0 Utp14 protein GAGA_bind PF06217.7 CDI74512.1 - 4.4 7.1 38.0 5.3 6.9 26.3 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family U79_P34 PF03064.11 CDI74512.1 - 6.9 6.1 29.5 9.4 5.6 20.5 1.3 1 0 0 1 1 1 0 HSV U79 / HCMV P34 GOLD_2 PF13897.1 CDI74513.1 - 0.014 15.6 0.8 0.015 15.5 0.6 1.1 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking LIM_bind PF01803.11 CDI74513.1 - 0.18 10.8 16.6 0.2 10.7 11.5 1.1 1 0 0 1 1 1 0 LIM-domain binding protein Cid2 PF09774.4 CDI74513.1 - 0.36 10.9 15.7 0.44 10.6 10.9 1.1 1 0 0 1 1 1 0 Caffeine-induced death protein 2 Toxin_R_bind_C PF07951.7 CDI74513.1 - 0.96 9.0 8.0 1 9.0 5.6 1.0 1 0 0 1 1 1 0 Clostridium neurotoxin, C-terminal receptor binding TT_ORF1 PF02956.9 CDI74513.1 - 1.8 6.9 14.2 2.1 6.7 9.8 1.0 1 0 0 1 1 1 0 TT viral orf 1 eIF-3_zeta PF05091.7 CDI74513.1 - 2.3 6.7 17.1 2.5 6.6 11.8 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) CPSF100_C PF13299.1 CDI74513.1 - 2.4 8.3 11.2 2.7 8.1 7.8 1.1 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal BTV_NS2 PF04514.7 CDI74513.1 - 2.6 6.8 13.4 2.9 6.6 9.3 1.0 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Baculo_PP31 PF05311.6 CDI74513.1 - 3.5 6.8 12.1 3.4 6.8 8.4 1.1 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) Cyto_heme_lyase PF01265.12 CDI74513.1 - 3.9 7.0 11.7 4.2 6.8 8.1 1.1 1 0 0 1 1 1 0 Cytochrome c/c1 heme lyase Kei1 PF08552.6 CDI74513.1 - 4.2 7.0 7.6 4.9 6.7 5.2 1.1 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 DDHD PF02862.12 CDI74513.1 - 4.3 7.0 11.2 4.8 6.9 7.7 1.1 1 0 0 1 1 1 0 DDHD domain Peptidase_U57 PF05582.7 CDI74513.1 - 4.4 6.1 10.5 4.6 6.1 7.3 1.1 1 0 0 1 1 1 0 YabG peptidase U57 HCO3_cotransp PF00955.16 CDI74513.1 - 4.6 5.7 5.0 5.3 5.5 3.4 1.0 1 0 0 1 1 1 0 HCO3- transporter family Band_3_cyto PF07565.8 CDI74513.1 - 5.1 6.5 14.9 6.9 6.1 10.3 1.3 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Gti1_Pac2 PF09729.4 CDI74513.1 - 5.6 6.7 10.3 6.5 6.5 7.1 1.1 1 0 0 1 1 1 0 Gti1/Pac2 family Peptidase_S49_N PF08496.5 CDI74513.1 - 6.5 6.5 13.5 7.7 6.2 9.3 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal FAM60A PF15396.1 CDI74513.1 - 7 6.3 10.2 7.9 6.1 7.1 1.1 1 0 0 1 1 1 0 Protein Family FAM60A AIF_C PF14721.1 CDI74513.1 - 7.5 6.7 9.5 9.2 6.5 6.6 1.3 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Glyco_transf_15 PF01793.11 CDI74513.1 - 7.6 5.3 13.4 9 5.1 9.3 1.0 1 0 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase YABBY PF04690.8 CDI74513.1 - 8 6.6 8.8 8.9 6.5 6.1 1.2 1 0 0 1 1 1 0 YABBY protein SpoVR PF04293.8 CDI74513.1 - 8.6 4.6 16.1 9.8 4.4 11.2 1.0 1 0 0 1 1 1 0 SpoVR like protein Mem_trans PF03547.13 CDI74513.1 - 9.6 4.3 6.5 9.8 4.3 4.5 1.1 1 0 0 1 1 1 0 Membrane transport protein DUF4220 PF13968.1 CDI74513.1 - 9.7 5.1 8.8 9.8 5.1 6.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4220) Thioredoxin_4 PF13462.1 CDI74513.1 - 9.8 6.1 12.7 13 5.7 8.8 1.2 1 0 0 1 1 1 0 Thioredoxin Hist_deacetyl PF00850.14 CDI74514.1 - 1.1e-13 51.1 2.0 1.2e-13 51.0 0.1 2.0 2 0 0 2 2 2 1 Histone deacetylase domain Ank_2 PF12796.2 CDI74514.1 - 3.6e-12 46.4 0.6 1.9e-08 34.4 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 CDI74514.1 - 1.8e-09 37.4 5.7 2.9e-08 33.6 0.7 3.7 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.25 CDI74514.1 - 2.3e-08 33.4 13.3 4.6e-06 26.1 0.7 4.5 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.1 CDI74514.1 - 1.5e-07 30.9 3.3 0.012 15.7 0.1 4.6 5 0 0 5 5 5 2 Ankyrin repeat Ank_4 PF13637.1 CDI74514.1 - 3.7e-07 30.4 6.2 0.00038 20.8 0.4 4.6 4 1 1 5 5 5 3 Ankyrin repeats (many copies) SUZ PF12752.2 CDI74514.1 - 5.5 7.5 0.0 5.5 7.5 0.0 4.5 4 1 0 4 4 4 0 SUZ domain Pex14_N PF04695.8 CDI74515.1 - 0.025 14.6 2.5 0.025 14.6 1.7 3.2 2 1 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF4145 PF13643.1 CDI74515.1 - 0.032 14.0 0.5 0.032 14.0 0.4 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF4145) ThiG PF05690.9 CDI74515.1 - 0.12 11.4 1.7 0.15 11.0 1.0 1.3 1 1 0 1 1 1 0 Thiazole biosynthesis protein ThiG DUF445 PF04286.7 CDI74515.1 - 0.77 9.2 20.3 1.1 8.7 14.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF445) Abhydrolase_9_N PF15420.1 CDI74515.1 - 3.6 7.2 8.4 10 5.7 5.7 1.8 1 1 0 1 1 1 0 Alpha/beta-hydrolase family N-terminus AP2 PF00847.15 CDI74519.1 - 0.00091 19.3 1.6 0.0018 18.3 1.1 1.4 1 0 0 1 1 1 1 AP2 domain Hist_deacetyl PF00850.14 CDI74520.1 - 0.36 10.0 3.6 0.82 8.8 2.5 1.6 1 0 0 1 1 1 0 Histone deacetylase domain Plasmodium_Vir PF05795.6 CDI74521.1 - 3 6.9 12.4 5 6.2 2.5 2.7 2 0 0 2 2 2 0 Plasmodium vivax Vir protein LMBR1 PF04791.11 CDI74522.1 - 9.4e-06 24.4 0.3 0.0069 15.0 0.0 2.7 2 1 0 2 2 2 2 LMBR1-like membrane protein CAF-1_p150 PF11600.3 CDI74523.1 - 0.0094 15.3 29.8 0.012 15.0 20.7 1.0 1 0 0 1 1 1 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal RR_TM4-6 PF06459.7 CDI74523.1 - 0.012 15.5 12.7 0.013 15.4 8.8 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 PAT1 PF09770.4 CDI74523.1 - 0.028 12.6 35.3 0.031 12.5 24.5 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Zip PF02535.17 CDI74523.1 - 0.035 13.1 14.8 0.045 12.7 10.2 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter DUF4337 PF14235.1 CDI74523.1 - 0.076 12.8 15.7 0.099 12.4 10.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Peptidase_S49_N PF08496.5 CDI74523.1 - 0.09 12.5 14.6 0.14 11.9 10.1 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal TRAP_alpha PF03896.11 CDI74523.1 - 0.15 11.0 3.6 0.2 10.6 2.5 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit SprA-related PF12118.3 CDI74523.1 - 0.22 10.8 41.2 0.27 10.5 28.6 1.0 1 0 0 1 1 1 0 SprA-related family Corona_nucleoca PF00937.13 CDI74523.1 - 0.25 10.2 27.2 0.39 9.6 18.8 1.3 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein Med15 PF09606.5 CDI74523.1 - 0.36 8.9 46.7 0.41 8.8 32.4 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF2052 PF09747.4 CDI74523.1 - 0.37 10.7 22.0 0.46 10.3 15.3 1.1 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) Raftlin PF15250.1 CDI74523.1 - 0.47 8.9 17.0 0.53 8.7 11.8 1.1 1 0 0 1 1 1 0 Raftlin TFIIA PF03153.8 CDI74523.1 - 0.48 10.2 30.2 0.58 10.0 20.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Asp-B-Hydro_N PF05279.6 CDI74523.1 - 0.53 10.0 11.0 0.55 10.0 7.6 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region FAM91_C PF14648.1 CDI74523.1 - 0.59 8.9 8.9 0.65 8.7 6.2 1.0 1 0 0 1 1 1 0 FAM91 C-terminus Ycf1 PF05758.7 CDI74523.1 - 0.66 7.6 17.7 0.74 7.4 12.3 1.1 1 0 0 1 1 1 0 Ycf1 Spore_coat_CotO PF14153.1 CDI74523.1 - 0.67 9.3 24.7 0.85 9.0 17.1 1.3 1 0 0 1 1 1 0 Spore coat protein CotO DUF3260 PF11658.3 CDI74523.1 - 0.7 7.9 14.0 0.84 7.7 9.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3260) Hex_IIIa PF02455.11 CDI74523.1 - 0.76 8.3 15.7 0.9 8.1 10.9 1.0 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) Parvo_coat PF00740.13 CDI74523.1 - 0.91 8.4 21.5 0.98 8.2 14.9 1.0 1 0 0 1 1 1 0 Parvovirus coat protein VP2 DUF4045 PF13254.1 CDI74523.1 - 1.2 8.3 20.1 1.8 7.7 14.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) DDHD PF02862.12 CDI74523.1 - 1.2 8.8 20.0 1.6 8.4 13.9 1.2 1 0 0 1 1 1 0 DDHD domain Serinc PF03348.10 CDI74523.1 - 1.2 7.7 15.1 1.5 7.4 10.5 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) FLO_LFY PF01698.11 CDI74523.1 - 1.3 7.8 18.6 1.5 7.6 12.9 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein SelP_N PF04592.9 CDI74523.1 - 1.5 8.1 24.9 2 7.7 17.3 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region DUF4175 PF13779.1 CDI74523.1 - 1.6 6.3 41.9 1.8 6.1 29.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Nucleoside_tran PF01733.13 CDI74523.1 - 1.6 7.8 5.6 1.8 7.6 3.9 1.2 1 0 0 1 1 1 0 Nucleoside transporter Peptidase_S15 PF02129.13 CDI74523.1 - 1.7 7.9 11.9 2 7.8 8.3 1.1 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) AvrE PF11725.3 CDI74523.1 - 1.8 5.4 22.9 2 5.3 15.9 1.0 1 0 0 1 1 1 0 Pathogenicity factor OmpH PF03938.9 CDI74523.1 - 2.3 8.1 33.9 2.7 7.9 23.5 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF3592 PF12158.3 CDI74523.1 - 2.4 7.9 9.2 3 7.6 6.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3592) Dynamin_N PF00350.18 CDI74523.1 - 2.7 7.7 10.3 3.7 7.3 7.1 1.3 1 0 0 1 1 1 0 Dynamin family SOBP PF15279.1 CDI74523.1 - 3.6 7.8 23.2 4.3 7.6 16.1 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein FimP PF09766.4 CDI74523.1 - 3.6 6.5 33.8 5.8 5.8 23.4 1.5 1 1 0 1 1 1 0 Fms-interacting protein DUF4220 PF13968.1 CDI74523.1 - 3.8 6.5 10.1 4.4 6.2 7.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4220) DDRGK PF09756.4 CDI74523.1 - 4.2 6.7 26.7 6.6 6.0 18.5 1.2 1 0 0 1 1 1 0 DDRGK domain DUF4011 PF13195.1 CDI74523.1 - 5.1 7.0 10.6 7 6.6 7.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4011) HCO3_cotransp PF00955.16 CDI74523.1 - 6.2 5.3 7.4 7.9 5.0 5.2 1.1 1 0 0 1 1 1 0 HCO3- transporter family GPCR_chapero_1 PF11904.3 CDI74523.1 - 6.5 5.7 18.1 8 5.4 12.5 1.1 1 0 0 1 1 1 0 GPCR-chaperone DUF2407_C PF13373.1 CDI74523.1 - 7.4 6.4 8.5 9.3 6.1 5.9 1.3 1 0 0 1 1 1 0 DUF2407 C-terminal domain DUF853 PF05872.7 CDI74523.1 - 7.8 4.7 13.4 8.8 4.5 9.3 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) Sec62 PF03839.11 CDI74523.1 - 7.8 5.8 13.6 9.5 5.5 9.4 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 eIF-3_zeta PF05091.7 CDI74523.1 - 8.3 4.9 23.9 9 4.7 16.6 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Hom_end_hint PF05203.11 CDI74523.1 - 9.3 5.9 14.4 12 5.5 10.0 1.3 1 0 0 1 1 1 0 Hom_end-associated Hint RCR PF12273.3 CDI74523.1 - 9.7 6.7 26.9 16 6.1 18.7 1.4 1 0 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red DHHW PF14286.1 CDI74523.1 - 9.8 5.3 15.9 11 5.1 11.0 1.2 1 0 0 1 1 1 0 DHHW protein DUF4175 PF13779.1 CDI74524.1 - 0.0007 17.4 35.5 0.00079 17.2 24.6 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4175) FAM163 PF15069.1 CDI74524.1 - 0.0064 17.0 6.2 0.007 16.9 4.3 1.2 1 0 0 1 1 1 1 FAM163 family MRP-S31 PF15433.1 CDI74524.1 - 0.0086 15.5 11.6 0.011 15.1 8.0 1.3 1 0 0 1 1 1 1 Mitochondrial 28S ribosomal protein S31 G-alpha PF00503.15 CDI74524.1 - 0.014 14.1 10.7 0.017 13.8 7.4 1.0 1 0 0 1 1 1 0 G-protein alpha subunit AUX_IAA PF02309.11 CDI74524.1 - 0.022 14.5 8.1 0.025 14.3 5.6 1.1 1 0 0 1 1 1 0 AUX/IAA family BRF1 PF07741.8 CDI74524.1 - 0.022 14.9 2.2 0.022 14.9 1.5 2.1 2 0 0 2 2 2 0 Brf1-like TBP-binding domain FLO_LFY PF01698.11 CDI74524.1 - 0.027 13.3 6.1 0.033 13.0 4.3 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein OAD_gamma PF04277.8 CDI74524.1 - 0.034 14.5 3.3 1.2 9.5 2.3 2.1 1 1 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain DDHD PF02862.12 CDI74524.1 - 0.035 13.9 7.5 0.044 13.5 5.2 1.1 1 0 0 1 1 1 0 DDHD domain eIF-3_zeta PF05091.7 CDI74524.1 - 0.058 12.0 14.0 0.064 11.8 9.7 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF3357 PF11837.3 CDI74524.1 - 0.081 12.7 5.7 1.9 8.3 0.2 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3357) Spore_YhcN_YlaJ PF09580.5 CDI74524.1 - 0.086 12.9 17.5 0.11 12.6 12.2 1.1 1 0 0 1 1 1 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) Glyco_transf_10 PF00852.14 CDI74524.1 - 0.093 11.2 12.2 0.22 10.0 8.4 1.6 1 1 1 2 2 2 0 Glycosyltransferase family 10 (fucosyltransferase) TT_ORF1 PF02956.9 CDI74524.1 - 0.11 10.9 8.7 0.12 10.8 6.0 1.0 1 0 0 1 1 1 0 TT viral orf 1 Dicty_REP PF05086.7 CDI74524.1 - 0.11 10.2 8.4 0.12 10.0 5.8 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Ribosomal_60s PF00428.14 CDI74524.1 - 0.12 12.7 2.8 0.17 12.2 1.9 1.3 1 0 0 1 1 1 0 60s Acidic ribosomal protein PAT1 PF09770.4 CDI74524.1 - 0.13 10.5 40.8 0.14 10.4 28.3 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Presenilin PF01080.12 CDI74524.1 - 0.13 11.0 3.8 0.15 10.8 2.6 1.1 1 0 0 1 1 1 0 Presenilin G-7-MTase PF12803.2 CDI74524.1 - 0.15 11.1 6.0 0.17 10.9 4.2 1.0 1 0 0 1 1 1 0 mRNA (guanine-7-)methyltransferase (G-7-MTase) Shisa PF13908.1 CDI74524.1 - 0.18 11.9 16.7 0.22 11.6 11.6 1.3 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator PIG-U PF06728.8 CDI74524.1 - 0.18 10.5 1.1 0.27 10.0 0.8 1.3 1 1 0 1 1 1 0 GPI transamidase subunit PIG-U GntP_permease PF02447.11 CDI74524.1 - 0.22 9.9 1.5 0.93 7.9 0.0 1.9 1 1 1 2 2 2 0 GntP family permease Lipase PF00151.14 CDI74524.1 - 0.24 10.5 9.2 0.27 10.4 6.4 1.1 1 0 0 1 1 1 0 Lipase AHS1 PF02682.11 CDI74524.1 - 0.26 10.7 6.7 0.3 10.5 4.7 1.1 1 0 0 1 1 1 0 Allophanate hydrolase subunit 1 DUF4045 PF13254.1 CDI74524.1 - 0.27 10.4 7.0 0.3 10.3 4.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Mit_KHE1 PF10173.4 CDI74524.1 - 0.33 10.7 7.1 0.4 10.5 4.9 1.2 1 0 0 1 1 1 0 Mitochondrial K+-H+ exchange-related Glyco_hydro_1 PF00232.13 CDI74524.1 - 0.38 8.8 4.3 0.42 8.7 3.0 1.0 1 0 0 1 1 1 0 Glycosyl hydrolase family 1 Zip PF02535.17 CDI74524.1 - 0.41 9.6 2.7 0.5 9.3 1.9 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Velvet PF11754.3 CDI74524.1 - 0.47 10.0 10.7 3 7.4 7.4 1.9 1 1 0 1 1 1 0 Velvet factor Mem_trans PF03547.13 CDI74524.1 - 0.48 8.6 2.8 0.61 8.3 2.0 1.3 1 0 0 1 1 1 0 Membrane transport protein DHHW PF14286.1 CDI74524.1 - 0.5 9.6 5.7 0.59 9.4 3.9 1.1 1 0 0 1 1 1 0 DHHW protein FNIP_N PF14636.1 CDI74524.1 - 0.53 10.7 13.5 0.81 10.1 9.4 1.2 1 0 0 1 1 1 0 Folliculin-interacting protein N-terminus Herpes_UL87 PF03043.9 CDI74524.1 - 0.55 8.5 7.2 0.61 8.4 5.0 1.0 1 0 0 1 1 1 0 Herpesvirus UL87 family TFIIA PF03153.8 CDI74524.1 - 0.69 9.7 27.5 0.83 9.4 19.1 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Caldesmon PF02029.10 CDI74524.1 - 0.75 8.1 9.8 0.97 7.7 6.8 1.1 1 0 0 1 1 1 0 Caldesmon Ycf1 PF05758.7 CDI74524.1 - 0.98 7.0 11.4 1.2 6.7 7.9 1.0 1 0 0 1 1 1 0 Ycf1 Rhabdo_glycop PF00974.13 CDI74524.1 - 1.1 7.3 7.4 1.9 6.6 0.4 2.0 1 1 1 2 2 2 0 Rhabdovirus spike glycoprotein SPX PF03105.14 CDI74524.1 - 1.2 8.9 10.4 1.5 8.5 7.2 1.2 1 0 0 1 1 1 0 SPX domain DUF605 PF04652.11 CDI74524.1 - 1.2 8.4 22.3 1.3 8.2 15.4 1.1 1 0 0 1 1 1 0 Vta1 like Lipoprotein_10 PF03202.8 CDI74524.1 - 1.5 8.8 9.8 2.1 8.3 6.8 1.2 1 0 0 1 1 1 0 Putative mycoplasma lipoprotein, C-terminal region TOM13 PF08219.6 CDI74524.1 - 1.5 8.6 5.9 10 5.9 0.5 2.2 2 0 0 2 2 2 0 Outer membrane protein TOM13 Hid1 PF12722.2 CDI74524.1 - 1.7 6.2 12.6 2 5.9 8.8 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein GRP PF07172.6 CDI74524.1 - 2 8.9 7.4 3 8.3 0.8 2.2 1 1 1 2 2 2 0 Glycine rich protein family DUF4647 PF15504.1 CDI74524.1 - 2 7.1 20.2 2.6 6.8 14.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4647) Calici_coat_C PF08435.6 CDI74524.1 - 2.3 7.4 9.7 2.9 7.1 6.8 1.2 1 0 0 1 1 1 0 Calicivirus coat protein C-terminal DUF3881 PF12997.2 CDI74524.1 - 2.4 7.1 7.2 3.1 6.7 5.0 1.2 1 0 0 1 1 1 0 Domain of unknown function, E. rectale Gene description (DUF3881) Conotoxin PF02950.12 CDI74524.1 - 2.8 8.7 17.6 1.4 9.7 3.0 2.3 1 1 1 2 2 2 0 Conotoxin DUF2265 PF10023.4 CDI74524.1 - 3 6.8 18.1 3.4 6.7 12.6 1.0 1 0 0 1 1 1 0 Predicted aminopeptidase (DUF2265) DUF3393 PF11873.3 CDI74524.1 - 3 7.2 14.7 8.6 5.8 10.3 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF3393) EphA2_TM PF14575.1 CDI74524.1 - 3.3 8.1 19.8 2.9 8.3 3.9 2.2 1 1 1 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Cyto_heme_lyase PF01265.12 CDI74524.1 - 3.8 7.0 15.0 4.9 6.6 10.4 1.1 1 0 0 1 1 1 0 Cytochrome c/c1 heme lyase Paramyxo_ncap PF00973.14 CDI74524.1 - 4.3 5.9 7.3 4.5 5.8 5.1 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein DUF1675 PF07897.6 CDI74524.1 - 5 6.9 8.0 6.7 6.4 5.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) Herpes_DNAp_acc PF04929.7 CDI74524.1 - 5.5 5.8 11.1 7.1 5.4 7.7 1.2 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Neur_chan_memb PF02932.11 CDI74524.1 - 5.6 6.7 10.6 8.1 6.2 7.4 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region XAP5 PF04921.9 CDI74524.1 - 5.7 6.4 11.7 7.2 6.0 8.1 1.1 1 0 0 1 1 1 0 XAP5, circadian clock regulator FAM195 PF14799.1 CDI74524.1 - 6.2 6.7 23.3 0.48 10.3 4.4 2.2 2 0 0 2 2 2 0 FAM195 family Neurensin PF14927.1 CDI74524.1 - 7.1 6.0 6.7 7.8 5.8 0.7 2.2 2 0 0 2 2 2 0 Neurensin TORC_M PF12885.2 CDI74524.1 - 7.5 6.2 11.1 9.2 6.0 7.7 1.2 1 0 0 1 1 1 0 Transducer of regulated CREB activity middle domain DUF4512 PF14975.1 CDI74524.1 - 7.7 7.4 10.5 13 6.6 7.3 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4512) DUF2956 PF11169.3 CDI74524.1 - 8.8 6.3 28.6 0.26 11.2 6.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2956) DUF3276 PF11680.3 CDI74524.1 - 9.8 5.9 11.3 8.3 6.2 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3276) VIT1 PF01988.14 CDI74525.1 - 0.064 12.7 4.5 0.12 11.8 3.1 1.5 1 0 0 1 1 1 0 VIT family AAA_23 PF13476.1 CDI74525.1 - 0.21 11.8 23.1 0.27 11.5 16.0 1.1 1 0 0 1 1 1 0 AAA domain Fasciclin PF02469.17 CDI74526.1 - 6.4e-07 29.4 9.7 4.5e-05 23.4 5.5 2.5 2 1 0 2 2 2 1 Fasciclin domain Med15 PF09606.5 CDI74526.1 - 0.00048 18.4 57.2 0.00048 18.4 39.6 1.9 2 0 0 2 2 2 1 ARC105 or Med15 subunit of Mediator complex non-fungal WBP-1 PF11669.3 CDI74526.1 - 0.03 14.3 0.2 0.03 14.3 0.1 3.5 2 1 1 3 3 1 0 WW domain-binding protein 1 MRP-S31 PF15433.1 CDI74526.1 - 0.23 10.8 20.6 0.033 13.6 10.9 1.8 2 0 0 2 2 2 0 Mitochondrial 28S ribosomal protein S31 NAD_binding_1 PF00175.16 CDI74526.1 - 0.56 10.8 8.9 0.51 10.9 5.0 1.7 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain AAA_23 PF13476.1 CDI74526.1 - 0.66 10.2 29.2 0.078 13.2 16.6 1.8 2 0 0 2 2 2 0 AAA domain DUF2347 PF09804.4 CDI74526.1 - 1.1 8.4 10.8 1.9 7.7 7.5 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2347) DUF4446 PF14584.1 CDI74526.1 - 1.3 8.8 17.7 4.8 7.0 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) Peptidase_S49_N PF08496.5 CDI74526.1 - 1.8 8.3 12.3 3.8 7.2 8.6 1.6 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Auxin_inducible PF02519.9 CDI74526.1 - 4.7 7.3 10.8 0.13 12.2 1.9 2.4 2 1 0 2 2 2 0 Auxin responsive protein Suf PF05843.9 CDI74526.1 - 7 6.2 18.9 0.57 9.8 9.9 1.6 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) RCC1 PF00415.13 CDI74527.1 - 1.8e-09 37.6 4.4 1.3e-07 31.7 0.1 3.9 4 0 0 4 4 4 1 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 CDI74527.1 - 2.5e-07 30.1 16.3 0.0029 17.1 0.3 4.1 4 0 0 4 4 4 3 Regulator of chromosome condensation (RCC1) repeat zf-RanBP PF00641.13 CDI74527.1 - 1.4e-05 24.0 5.4 3.4e-05 22.8 3.8 1.6 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others Herpes_BLLF1 PF05109.8 CDI74529.1 - 0.013 13.5 24.8 0.013 13.4 17.2 1.0 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) SOBP PF15279.1 CDI74529.1 - 0.044 14.1 4.9 0.061 13.7 3.4 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein Suf PF05843.9 CDI74529.1 - 0.41 10.3 3.5 0.45 10.1 2.4 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF3115 PF11312.3 CDI74529.1 - 0.5 9.1 3.5 0.66 8.7 2.4 1.2 1 1 0 1 1 1 0 Protein of unknown function (DUF3115) Med13_C PF06333.7 CDI74529.1 - 0.56 8.6 6.8 0.61 8.5 4.7 1.1 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal SseC PF04888.7 CDI74529.1 - 0.74 9.0 31.9 0.96 8.7 22.1 1.0 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family TFIIA PF03153.8 CDI74529.1 - 1.8 8.3 23.2 2.3 8.0 16.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Med15 PF09606.5 CDI74529.1 - 3.3 5.7 22.3 3.9 5.5 15.4 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Ribosomal_60s PF00428.14 CDI74531.1 - 0.0059 16.9 12.7 0.01 16.1 8.8 1.4 1 0 0 1 1 1 1 60s Acidic ribosomal protein Spt20 PF12090.3 CDI74531.1 - 0.012 14.9 2.4 0.013 14.8 1.7 1.1 1 0 0 1 1 1 0 Spt20 family FCP1_C PF09309.5 CDI74531.1 - 0.014 14.7 5.0 0.017 14.4 3.5 1.1 1 0 0 1 1 1 0 FCP1, C-terminal Med15 PF09606.5 CDI74531.1 - 0.021 13.0 18.9 0.027 12.7 13.1 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Pex16 PF08610.5 CDI74531.1 - 0.12 11.3 3.1 0.13 11.2 2.2 1.1 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) TMEM51 PF15345.1 CDI74531.1 - 0.13 11.9 8.2 0.16 11.6 5.7 1.1 1 0 0 1 1 1 0 Transmembrane protein 51 Tnp_P_element PF12017.3 CDI74531.1 - 0.24 10.5 2.2 0.3 10.2 1.5 1.2 1 0 0 1 1 1 0 Transposase protein Cytochrome-c551 PF10643.4 CDI74531.1 - 0.59 9.3 2.8 0.72 9.1 1.9 1.2 1 0 0 1 1 1 0 Photosystem P840 reaction-centre cytochrome c-551 DUF243 PF03103.12 CDI74531.1 - 1.2 9.3 6.7 3.4 7.8 4.6 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF243) CWC25 PF12542.3 CDI74531.1 - 1.4 9.4 14.4 1.4 9.3 7.2 2.2 2 0 0 2 2 2 0 Pre-mRNA splicing factor RAB3GAP2_N PF14655.1 CDI74531.1 - 2.6 6.9 10.8 0.41 9.6 3.9 1.8 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Ycf1 PF05758.7 CDI74533.1 - 1.7e-05 22.8 27.7 2.2e-05 22.4 19.2 1.2 1 0 0 1 1 1 1 Ycf1 FA_desaturase PF00487.19 CDI74533.1 - 0.0073 15.7 0.2 0.011 15.1 0.1 1.2 1 0 0 1 1 1 1 Fatty acid desaturase Herpes_UL87 PF03043.9 CDI74533.1 - 0.048 12.0 10.6 0.061 11.6 7.3 1.2 1 0 0 1 1 1 0 Herpesvirus UL87 family SAGA-Tad1 PF12767.2 CDI74533.1 - 1.3 8.6 38.6 1.7 8.2 26.8 1.2 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit Pex24p PF06398.6 CDI74533.1 - 1.7 7.3 20.9 32 3.1 14.5 2.2 1 1 0 1 1 1 0 Integral peroxisomal membrane peroxin Utp11 PF03998.8 CDI74533.1 - 2.3 7.9 48.9 3 7.6 33.9 1.0 1 0 0 1 1 1 0 Utp11 protein SpoIIIAH PF12685.2 CDI74533.1 - 3.6 7.0 38.3 23 4.4 26.5 2.0 1 1 0 1 1 1 0 SpoIIIAH-like protein DUF2201_N PF13203.1 CDI74533.1 - 3.9 6.5 40.4 5.1 6.1 28.0 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain FLO_LFY PF01698.11 CDI74533.1 - 6.1 5.5 41.1 10 4.8 28.5 1.3 1 0 0 1 1 1 0 Floricaula / Leafy protein DUF1510 PF07423.6 CDI74533.1 - 6.4 6.0 53.1 29 3.9 36.8 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1510) Utp14 PF04615.8 CDI74533.1 - 6.9 4.7 51.5 8.4 4.4 35.7 1.0 1 0 0 1 1 1 0 Utp14 protein MIP-T3 PF10243.4 CDI74533.1 - 8.6 4.6 58.6 10 4.4 40.6 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DUF1917 PF08939.5 CDI74534.1 - 0.49 10.1 15.0 0.64 9.7 10.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1917) PAT1 PF09770.4 CDI74534.1 - 0.63 8.2 42.2 0.77 7.9 29.3 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Ndc1_Nup PF09531.5 CDI74534.1 - 0.75 8.1 19.1 0.89 7.8 13.2 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF1645 PF07816.6 CDI74534.1 - 1.1 9.6 14.8 7.3 6.9 10.0 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1645) Spore_coat_CotO PF14153.1 CDI74534.1 - 2.1 7.7 29.0 1.5 8.1 9.9 2.0 2 0 0 2 2 2 0 Spore coat protein CotO DUF1151 PF06625.6 CDI74534.1 - 3.1 7.5 29.6 1.8 8.3 10.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1151) Bul1_C PF04426.7 CDI74534.1 - 3.6 6.7 13.2 4.6 6.3 9.2 1.1 1 0 0 1 1 1 0 Bul1 C terminus DUF3408 PF11888.3 CDI74534.1 - 4.4 7.2 21.2 1.1 9.1 3.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3408) DUF1764 PF08576.5 CDI74534.1 - 5.4 7.8 20.5 5.5 7.8 2.9 2.2 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF1764) FNIP_N PF14636.1 CDI74534.1 - 8.7 6.8 18.9 4.9 7.6 4.9 2.1 2 0 0 2 2 2 0 Folliculin-interacting protein N-terminus UCH PF00443.24 CDI74535.1 - 5.1e-26 91.3 0.0 5.1e-26 91.3 0.0 3.4 4 0 0 4 4 4 1 Ubiquitin carboxyl-terminal hydrolase Epimerase PF01370.16 CDI74537.1 - 9.9e-61 205.1 0.0 1.1e-60 204.9 0.0 1.0 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 CDI74537.1 - 1.1e-10 40.8 0.0 1.5e-10 40.4 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 CDI74537.1 - 0.0014 17.5 0.0 0.0027 16.6 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.8 CDI74537.1 - 0.0023 17.2 0.0 0.0039 16.4 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 CDI74537.1 - 0.072 13.0 0.0 0.14 12.1 0.0 1.5 1 1 0 1 1 1 0 NADH(P)-binding Suf PF05843.9 CDI74538.1 - 0.14 11.8 8.8 0.2 11.3 6.1 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Presenilin PF01080.12 CDI74538.1 - 1.1 8.0 11.1 1.6 7.4 7.7 1.2 1 0 0 1 1 1 0 Presenilin Hex_IIIa PF02455.11 CDI74538.1 - 1.5 7.4 9.4 2.1 6.9 6.5 1.2 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) FimP PF09766.4 CDI74538.1 - 2.1 7.3 13.3 0.57 9.1 5.0 2.0 2 0 0 2 2 2 0 Fms-interacting protein FAM176 PF14851.1 CDI74538.1 - 2.3 7.8 11.8 1 9.0 2.5 2.2 2 0 0 2 2 2 0 FAM176 family Med15 PF09606.5 CDI74538.1 - 4 5.5 32.7 3.7 5.6 21.9 1.5 1 1 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF1510 PF07423.6 CDI74539.1 - 0.0087 15.4 7.1 0.011 15.1 4.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) Ycf1 PF05758.7 CDI74539.1 - 0.086 10.5 1.1 0.088 10.5 0.8 1.0 1 0 0 1 1 1 0 Ycf1 COX16 PF14138.1 CDI74539.1 - 5.4 7.2 5.5 1.3e+02 2.8 3.8 2.2 1 1 0 1 1 1 0 Cytochrome c oxidase assembly protein COX16 K_channel_TID PF07941.6 CDI74540.1 - 0.0033 17.6 10.3 0.0033 17.6 7.1 15.2 9 4 3 12 12 12 2 Potassium channel Kv1.4 tandem inactivation domain CAF-1_p150 PF11600.3 CDI74540.1 - 0.014 14.7 1.0 0.014 14.7 0.7 8.3 4 1 2 6 6 6 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Ribosomal_60s PF00428.14 CDI74540.1 - 0.023 15.0 2.1 0.023 15.0 1.5 14.1 9 2 2 11 11 11 0 60s Acidic ribosomal protein BAF1_ABF1 PF04684.8 CDI74541.1 - 0.00048 19.1 42.8 0.00094 18.1 15.8 15.9 10 4 5 15 15 15 3 BAF1 / ABF1 chromatin reorganising factor FimP PF09766.4 CDI74541.1 - 0.00061 18.9 10.1 0.00061 18.9 7.0 10.0 7 2 3 10 10 10 3 Fms-interacting protein Med15 PF09606.5 CDI74542.1 - 0.0051 15.0 121.0 0.0058 14.8 83.9 1.0 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal Utp14 PF04615.8 CDI74542.1 - 0.069 11.3 50.4 0.078 11.1 35.0 1.0 1 0 0 1 1 1 0 Utp14 protein SAGA-Tad1 PF12767.2 CDI74542.1 - 0.18 11.4 52.1 0.23 11.0 36.1 1.1 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit Exonuc_VII_L PF02601.10 CDI74542.1 - 0.21 10.7 42.1 0.26 10.4 29.2 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit GAGA_bind PF06217.7 CDI74542.1 - 0.25 11.2 39.6 0.31 10.9 27.4 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family PAT1 PF09770.4 CDI74542.1 - 0.3 9.2 99.5 0.36 9.0 69.0 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SAPS PF04499.10 CDI74542.1 - 0.47 9.0 32.8 0.57 8.7 22.7 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein BTV_NS2 PF04514.7 CDI74542.1 - 1.1 8.0 31.2 1.3 7.7 21.6 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Parvo_coat PF00740.13 CDI74542.1 - 2.7 6.8 44.7 3.3 6.5 31.0 1.1 1 0 0 1 1 1 0 Parvovirus coat protein VP2 CDC45 PF02724.9 CDI74542.1 - 5.6 4.8 45.1 7.6 4.4 31.2 1.2 1 0 0 1 1 1 0 CDC45-like protein Daxx PF03344.10 CDI74542.1 - 7.3 4.9 44.9 8.9 4.6 31.1 1.1 1 0 0 1 1 1 0 Daxx Family Draxin PF15550.1 CDI74542.1 - 7.5 6.1 34.5 11 5.6 23.9 1.3 1 0 0 1 1 1 0 Draxin PA26 PF04636.8 CDI74542.1 - 7.6 5.1 27.6 8.3 4.9 19.2 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Ycf1 PF05758.7 CDI74542.1 - 8.6 3.9 44.8 11 3.6 31.1 1.1 1 0 0 1 1 1 0 Ycf1 Paramyxo_ncap PF00973.14 CDI74542.1 - 8.7 4.9 39.0 11 4.5 27.0 1.2 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein PLRV_ORF5 PF01690.12 CDI74542.1 - 9.8 5.1 43.4 11 5.0 30.1 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein CAF-1_p150 PF11600.3 CDI74543.1 - 0.0021 17.4 31.1 0.0037 16.6 21.4 1.4 1 1 0 1 1 1 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal Med15 PF09606.5 CDI74543.1 - 0.0024 16.2 41.7 0.0027 16.0 28.9 1.1 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal SOBP PF15279.1 CDI74543.1 - 0.013 15.8 18.5 0.016 15.6 12.8 1.0 1 0 0 1 1 1 0 Sine oculis-binding protein Activator_LAG-3 PF11498.3 CDI74543.1 - 0.046 12.4 39.9 0.065 11.9 27.7 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 PAT1 PF09770.4 CDI74543.1 - 0.18 10.0 35.0 0.2 9.8 24.3 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Daxx PF03344.10 CDI74543.1 - 0.47 8.8 26.7 0.55 8.6 18.5 1.0 1 0 0 1 1 1 0 Daxx Family DUF4647 PF15504.1 CDI74543.1 - 0.66 8.7 19.8 0.82 8.4 13.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4647) Asp-B-Hydro_N PF05279.6 CDI74543.1 - 0.74 9.6 17.3 0.87 9.3 12.0 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region PPP4R2 PF09184.6 CDI74543.1 - 0.9 9.0 18.6 1.2 8.5 12.9 1.3 1 0 0 1 1 1 0 PPP4R2 SAGA-Tad1 PF12767.2 CDI74543.1 - 0.98 9.0 22.4 1.3 8.6 15.5 1.2 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit AAA_23 PF13476.1 CDI74543.1 - 1.8 8.8 17.7 2.8 8.2 12.3 1.3 1 0 0 1 1 1 0 AAA domain CDK5_activator PF03261.10 CDI74543.1 - 2.3 7.4 23.9 3.1 7.0 16.6 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein Utp14 PF04615.8 CDI74543.1 - 2.4 6.2 28.4 2.8 5.9 19.7 1.0 1 0 0 1 1 1 0 Utp14 protein GAGA_bind PF06217.7 CDI74543.1 - 4 7.3 17.7 5.2 6.9 12.3 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family DUF4175 PF13779.1 CDI74543.1 - 5.9 4.4 44.8 7.1 4.1 31.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) PLRV_ORF5 PF01690.12 CDI74543.1 - 6 5.9 21.9 7.4 5.5 15.2 1.2 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein LMBR1 PF04791.11 CDI74543.1 - 6.3 5.2 6.3 7.4 5.0 4.4 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Corona_nucleoca PF00937.13 CDI74543.1 - 8.8 5.1 28.6 0.96 8.3 16.7 1.6 1 1 0 1 1 1 0 Coronavirus nucleocapsid protein DUF3584 PF12128.3 CDI74543.1 - 8.8 3.4 33.7 11 3.2 23.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Borrelia_P83 PF05262.6 CDI74543.1 - 9.8 4.3 24.2 11 4.1 16.8 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Nrap PF03813.9 CDI74544.1 - 2e-10 38.9 0.1 2.7e-10 38.5 0.0 1.1 1 0 0 1 1 1 1 Nrap protein DUF2726 PF10881.3 CDI74544.1 - 0.027 14.0 0.1 0.058 13.0 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2726) RNase_H2-Ydr279 PF09468.5 CDI74545.1 - 1.6e-13 50.5 0.0 9.2e-13 48.0 0.0 1.9 1 1 0 1 1 1 1 Ydr279p protein family (RNase H2 complex component) DUF755 PF05501.6 CDI74546.1 - 0.0097 15.9 18.1 0.0097 15.9 12.5 4.1 2 2 1 3 3 1 1 Domain of unknown function (DUF755) Daxx PF03344.10 CDI74546.1 - 0.022 13.2 32.7 0.03 12.8 22.6 1.2 1 0 0 1 1 1 0 Daxx Family TFIIA PF03153.8 CDI74546.1 - 0.052 13.4 57.4 0.17 11.7 26.8 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Vfa1 PF08432.5 CDI74546.1 - 0.69 9.9 36.7 0.76 9.7 18.4 2.2 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 AUX_IAA PF02309.11 CDI74546.1 - 2.1 8.0 30.8 0.88 9.2 13.0 2.3 2 0 0 2 2 2 0 AUX/IAA family DUF3807 PF12720.2 CDI74546.1 - 2.6 8.1 42.8 1.9 8.6 20.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3807) DUF2052 PF09747.4 CDI74546.1 - 2.6 7.9 40.5 2.1 8.2 1.4 2.2 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) Neur_chan_memb PF02932.11 CDI74546.1 - 4 7.2 31.5 0.77 9.5 1.8 2.1 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region SAPS PF04499.10 CDI74546.1 - 4.4 5.8 33.9 3.3 6.2 15.5 2.0 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein Parvo_coat PF00740.13 CDI74546.1 - 5.7 5.7 32.6 2.1 7.2 15.8 2.0 2 0 0 2 2 2 0 Parvovirus coat protein VP2 DUF1510 PF07423.6 CDI74546.1 - 6.1 6.1 48.0 4.1 6.6 5.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) Apt1 PF10351.4 CDI74546.1 - 6.6 5.4 46.6 0.077 11.8 9.6 2.1 2 0 0 2 2 2 0 Golgi-body localisation protein domain DDRGK PF09756.4 CDI74546.1 - 7.3 5.9 45.7 2.6 7.4 26.6 2.1 2 0 0 2 2 2 0 DDRGK domain DUF1510 PF07423.6 CDI74547.1 - 0.062 12.6 25.4 0.061 12.6 17.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) PPP4R2 PF09184.6 CDI74547.1 - 0.32 10.5 22.3 0.34 10.4 15.4 1.0 1 0 0 1 1 1 0 PPP4R2 DUF3987 PF13148.1 CDI74547.1 - 0.68 8.4 15.4 0.8 8.2 10.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) SR-25 PF10500.4 CDI74547.1 - 0.95 8.8 25.6 1.2 8.5 17.7 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Baculo_PP31 PF05311.6 CDI74547.1 - 1.2 8.3 22.9 1.4 8.1 15.9 1.2 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) Pneumo_phosprot PF02478.11 CDI74547.1 - 1.3 8.5 10.9 1.4 8.3 7.6 1.1 1 0 0 1 1 1 0 Pneumovirus phosphoprotein FLO_LFY PF01698.11 CDI74547.1 - 1.3 7.7 23.4 1.4 7.6 16.2 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein Zip PF02535.17 CDI74547.1 - 1.5 7.7 9.7 1.5 7.7 6.8 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter SprA-related PF12118.3 CDI74547.1 - 1.7 7.9 56.3 2 7.6 39.0 1.1 1 0 0 1 1 1 0 SprA-related family Ycf1 PF05758.7 CDI74547.1 - 1.8 6.1 24.9 1.8 6.1 17.3 1.0 1 0 0 1 1 1 0 Ycf1 GAGA_bind PF06217.7 CDI74547.1 - 1.9 8.3 24.1 2.1 8.2 16.7 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family NARP1 PF12569.3 CDI74547.1 - 1.9 7.1 27.7 2 7.0 19.2 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 BTV_NS2 PF04514.7 CDI74547.1 - 2.8 6.7 22.0 2.8 6.7 15.2 1.0 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 YABBY PF04690.8 CDI74547.1 - 2.9 8.0 16.9 3.6 7.7 11.7 1.2 1 0 0 1 1 1 0 YABBY protein PCEMA1 PF07418.6 CDI74547.1 - 3 7.1 12.6 3.3 6.9 8.7 1.2 1 0 0 1 1 1 0 Acidic phosphoprotein precursor PCEMA1 Herpes_DNAp_acc PF04929.7 CDI74547.1 - 3.9 6.3 23.1 4.5 6.1 16.0 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Hamartin PF04388.7 CDI74547.1 - 3.9 6.0 21.1 4.2 5.9 14.6 1.0 1 0 0 1 1 1 0 Hamartin protein SpoVR PF04293.8 CDI74547.1 - 4 5.7 20.7 3.9 5.7 14.4 1.1 1 0 0 1 1 1 0 SpoVR like protein DDHD PF02862.12 CDI74547.1 - 4.8 6.9 25.2 6 6.6 17.5 1.2 1 0 0 1 1 1 0 DDHD domain CobT PF06213.7 CDI74547.1 - 4.9 6.2 20.7 4.8 6.2 14.4 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Pox_Ag35 PF03286.9 CDI74547.1 - 5.9 6.3 21.7 6.5 6.2 15.0 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein PMSI1 PF15322.1 CDI74547.1 - 6.3 5.7 20.1 7 5.6 14.0 1.1 1 0 0 1 1 1 0 Protein missing in infertile sperm 1, putative DUF2126 PF09899.4 CDI74547.1 - 8.3 4.3 20.8 9.3 4.1 14.4 1.0 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) SprA-related PF12118.3 CDI74548.1 - 0.004 16.5 11.2 0.004 16.5 7.8 3.9 2 1 1 3 3 3 1 SprA-related family HEAT PF02985.17 CDI74548.1 - 0.005 16.8 3.6 0.053 13.6 0.1 4.2 4 0 0 4 4 4 1 HEAT repeat Conotoxin PF02950.12 CDI74549.1 - 0.0016 19.1 6.3 0.0016 19.1 4.4 2.2 1 1 1 2 2 2 1 Conotoxin DUF1510 PF07423.6 CDI74549.1 - 0.0041 16.5 19.3 0.0043 16.4 13.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) FAM176 PF14851.1 CDI74549.1 - 0.0079 15.8 8.6 0.011 15.3 6.0 1.3 1 0 0 1 1 1 1 FAM176 family SpoIIIAH PF12685.2 CDI74549.1 - 0.0097 15.4 17.3 0.011 15.2 12.0 1.1 1 0 0 1 1 1 1 SpoIIIAH-like protein TRAP_alpha PF03896.11 CDI74549.1 - 0.024 13.6 3.6 0.027 13.4 2.5 1.0 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit RIC3 PF15361.1 CDI74549.1 - 0.037 14.2 12.7 0.044 14.0 8.8 1.3 1 0 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 DUF3393 PF11873.3 CDI74549.1 - 0.044 13.2 11.6 0.047 13.1 8.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3393) TMEM51 PF15345.1 CDI74549.1 - 0.048 13.3 20.4 0.052 13.2 14.2 1.1 1 0 0 1 1 1 0 Transmembrane protein 51 OAD_gamma PF04277.8 CDI74549.1 - 0.062 13.6 4.5 0.23 11.8 3.1 1.9 1 1 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain Protocadherin PF08374.6 CDI74549.1 - 0.065 12.8 9.4 0.072 12.7 6.5 1.0 1 0 0 1 1 1 0 Protocadherin Gastrin PF00918.12 CDI74549.1 - 0.17 12.7 20.7 0.19 12.5 14.4 1.1 1 0 0 1 1 1 0 Gastrin/cholecystokinin family Tmemb_9 PF05434.6 CDI74549.1 - 0.43 10.3 10.9 0.48 10.1 7.6 1.2 1 0 0 1 1 1 0 TMEM9 PSI_PsaF PF02507.10 CDI74549.1 - 0.64 9.5 5.6 0.74 9.3 3.9 1.1 1 0 0 1 1 1 0 Photosystem I reaction centre subunit III Mucin PF01456.12 CDI74549.1 - 0.67 9.7 8.3 1.2 8.9 5.7 1.4 1 1 0 1 1 1 0 Mucin-like glycoprotein ExbD PF02472.11 CDI74549.1 - 0.91 9.5 8.3 1.2 9.1 5.7 1.3 1 0 0 1 1 1 0 Biopolymer transport protein ExbD/TolR Mem_trans PF03547.13 CDI74549.1 - 0.96 7.6 11.9 0.94 7.7 8.3 1.0 1 0 0 1 1 1 0 Membrane transport protein Tetraspannin PF00335.15 CDI74549.1 - 1.1 8.4 7.3 1.3 8.1 5.1 1.1 1 0 0 1 1 1 0 Tetraspanin family YfhO PF09586.5 CDI74549.1 - 1.1 7.1 12.0 1.4 6.8 8.3 1.2 1 0 0 1 1 1 0 Bacterial membrane protein YfhO DUF2782 PF11191.3 CDI74549.1 - 1.2 9.1 10.6 8.7 6.3 7.4 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF2782) K_trans PF02705.11 CDI74549.1 - 1.2 7.3 5.0 1.3 7.3 3.5 1.0 1 0 0 1 1 1 0 K+ potassium transporter GRP PF07172.6 CDI74549.1 - 1.4 9.4 10.5 21 5.6 7.3 2.1 1 1 0 1 1 1 0 Glycine rich protein family Endonuc_Holl PF10107.4 CDI74549.1 - 1.5 8.4 15.3 2.1 7.9 10.6 1.3 1 0 0 1 1 1 0 Endonuclease related to archaeal Holliday junction resolvase PepSY_2 PF13670.1 CDI74549.1 - 1.6 8.7 8.0 18 5.2 5.5 2.2 1 1 0 1 1 1 0 Peptidase propeptide and YPEB domain Zip PF02535.17 CDI74549.1 - 1.8 7.5 6.5 2.2 7.2 4.5 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter DUF3357 PF11837.3 CDI74549.1 - 1.9 8.3 15.1 0.62 9.9 2.7 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF3357) SID-1_RNA_chan PF13965.1 CDI74549.1 - 2 6.5 12.8 2.1 6.4 8.8 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DUF4446 PF14584.1 CDI74549.1 - 2.9 7.6 9.0 3.5 7.4 6.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) ALG3 PF05208.8 CDI74549.1 - 3 6.9 4.6 3.2 6.8 3.2 1.2 1 0 0 1 1 1 0 ALG3 protein DUF2215 PF10225.4 CDI74549.1 - 3.7 6.9 12.1 4.6 6.6 8.4 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) DUF501 PF04417.7 CDI74549.1 - 4.2 7.2 7.5 4.8 7.0 5.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF501) DUF3260 PF11658.3 CDI74549.1 - 4.5 5.3 15.3 5 5.1 10.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3260) PSK PF06404.7 CDI74549.1 - 4.7 8.0 17.8 0.35 11.6 3.5 2.1 1 1 1 2 2 2 0 Phytosulfokine precursor protein (PSK) Myc_target_1 PF15179.1 CDI74549.1 - 4.7 6.7 13.5 4.8 6.7 9.4 1.1 1 0 0 1 1 1 0 Myc target protein 1 FHIPEP PF00771.15 CDI74549.1 - 5.2 5.2 14.7 5.5 5.1 10.2 1.1 1 0 0 1 1 1 0 FHIPEP family Sex_peptide PF08138.6 CDI74549.1 - 5.7 6.8 6.8 20 5.1 4.6 2.2 1 1 0 1 1 1 0 Sex peptide (SP) family SLD3 PF08639.5 CDI74549.1 - 6.2 5.3 30.0 6.7 5.2 20.8 1.0 1 0 0 1 1 1 0 DNA replication regulator SLD3 MMR1 PF08505.5 CDI74549.1 - 6.3 6.7 28.7 6.9 6.6 19.9 1.1 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein CobT PF06213.7 CDI74549.1 - 6.4 5.8 19.4 7.9 5.5 13.5 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Plasmodium_Vir PF05795.6 CDI74549.1 - 6.9 5.7 13.2 7.8 5.5 9.2 1.0 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Serinc PF03348.10 CDI74549.1 - 7.4 5.1 18.8 9.8 4.7 13.0 1.4 1 1 0 1 1 1 0 Serine incorporator (Serinc) Stig1 PF04885.8 CDI74549.1 - 8.2 6.6 13.5 31 4.7 9.3 1.8 1 1 0 1 1 1 0 Stigma-specific protein, Stig1 FliP PF00813.15 CDI74549.1 - 8.3 6.0 8.8 9.1 5.9 6.1 1.1 1 0 0 1 1 1 0 FliP family Presenilin PF01080.12 CDI74549.1 - 8.5 5.0 16.6 8.9 5.0 11.5 1.1 1 0 0 1 1 1 0 Presenilin Otopetrin PF03189.8 CDI74549.1 - 9.2 5.1 11.9 10 5.0 8.2 1.0 1 0 0 1 1 1 0 Otopetrin XPG_N PF00752.12 CDI74550.1 - 5.5e-08 32.9 3.4 4.3e-07 30.1 2.4 2.3 1 1 0 1 1 1 1 XPG N-terminal domain CD20 PF04103.10 CDI74550.1 - 0.0022 17.9 0.8 0.0029 17.5 0.6 1.2 1 0 0 1 1 1 1 CD20-like family DUF2512 PF10710.4 CDI74550.1 - 0.016 14.6 1.4 0.02 14.3 1.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2512) Pex14_N PF04695.8 CDI74550.1 - 0.017 15.2 8.0 0.021 14.8 5.5 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Med15 PF09606.5 CDI74550.1 - 0.02 13.1 18.2 0.02 13.0 12.6 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal FAM222A PF15258.1 CDI74550.1 - 0.021 14.0 8.8 0.024 13.8 6.1 1.0 1 0 0 1 1 1 0 Protein family of FAM222A Spt20 PF12090.3 CDI74550.1 - 0.024 13.9 2.7 0.023 14.0 1.9 1.1 1 0 0 1 1 1 0 Spt20 family DUF912 PF06024.7 CDI74550.1 - 0.025 14.6 1.6 0.03 14.3 1.1 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) AIF_C PF14721.1 CDI74550.1 - 0.027 14.7 3.1 0.034 14.3 2.1 1.1 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term DUF3260 PF11658.3 CDI74550.1 - 0.034 12.2 2.8 0.04 12.0 2.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3260) SprA-related PF12118.3 CDI74550.1 - 0.041 13.2 16.5 0.044 13.1 11.4 1.1 1 0 0 1 1 1 0 SprA-related family RskA PF10099.4 CDI74550.1 - 0.042 13.5 8.0 0.052 13.2 5.6 1.1 1 0 0 1 1 1 0 Anti-sigma-K factor rskA Peptidase_U57 PF05582.7 CDI74550.1 - 0.044 12.7 2.6 0.049 12.6 1.8 1.0 1 0 0 1 1 1 0 YabG peptidase U57 PAT1 PF09770.4 CDI74550.1 - 0.049 11.8 13.5 0.05 11.8 9.4 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Suf PF05843.9 CDI74550.1 - 0.05 13.3 5.5 0.048 13.3 3.8 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF913 PF06025.7 CDI74550.1 - 0.05 12.3 0.8 0.059 12.1 0.6 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Trp_oprn_chp PF09534.5 CDI74550.1 - 0.052 13.1 5.3 0.056 13.0 3.7 1.1 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) FimP PF09766.4 CDI74550.1 - 0.053 12.5 11.5 0.062 12.3 8.0 1.1 1 0 0 1 1 1 0 Fms-interacting protein Zip PF02535.17 CDI74550.1 - 0.061 12.3 0.8 0.06 12.3 0.6 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter FHIPEP PF00771.15 CDI74550.1 - 0.061 11.6 2.7 0.064 11.5 1.9 1.1 1 0 0 1 1 1 0 FHIPEP family RIC3 PF15361.1 CDI74550.1 - 0.07 13.3 3.8 0.088 13.0 2.6 1.1 1 0 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 Gag_spuma PF03276.9 CDI74550.1 - 0.08 11.2 8.3 0.085 11.1 5.8 1.0 1 0 0 1 1 1 0 Spumavirus gag protein Serinc PF03348.10 CDI74550.1 - 0.081 11.6 3.9 0.089 11.4 2.7 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) TFIIA PF03153.8 CDI74550.1 - 0.083 12.7 10.2 0.081 12.8 7.1 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4557 PF15101.1 CDI74550.1 - 0.15 11.8 8.6 0.16 11.8 5.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) Ctr PF04145.10 CDI74550.1 - 0.17 11.8 1.4 0.2 11.6 1.0 1.1 1 0 0 1 1 1 0 Ctr copper transporter family Adeno_PIX PF03955.9 CDI74550.1 - 0.29 11.6 4.0 0.34 11.4 2.8 1.1 1 0 0 1 1 1 0 Adenovirus hexon-associated protein (IX) Glt_symporter PF03616.9 CDI74550.1 - 0.31 9.4 2.1 0.37 9.2 1.5 1.1 1 0 0 1 1 1 0 Sodium/glutamate symporter DUF1360 PF07098.6 CDI74550.1 - 0.33 10.6 2.8 0.45 10.2 1.5 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1360) R_equi_Vir PF05526.6 CDI74550.1 - 0.41 10.2 5.1 0.52 9.9 3.6 1.2 1 0 0 1 1 1 0 Rhodococcus equi virulence-associated protein OATP PF03137.15 CDI74550.1 - 0.43 8.5 2.1 0.47 8.4 1.5 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family EIIBC-GUT_N PF03612.9 CDI74550.1 - 0.43 10.1 3.0 0.49 9.9 2.1 1.1 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus CBP4 PF07960.6 CDI74550.1 - 0.46 10.1 8.8 0.67 9.5 6.1 1.3 1 0 0 1 1 1 0 CBP4 DUF4175 PF13779.1 CDI74550.1 - 0.54 7.9 17.1 0.63 7.6 11.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) UPF0560 PF10577.4 CDI74550.1 - 0.68 8.1 13.3 0.75 7.9 9.2 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 OmpH PF03938.9 CDI74550.1 - 1.3 8.9 20.5 1.9 8.4 14.2 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Sin_N PF04801.8 CDI74551.1 - 2.3e-16 59.6 1.4 2.3e-16 59.6 1.0 4.1 3 2 0 3 3 3 1 Sin-like protein conserved region DUF2722 PF10846.3 CDI74551.1 - 0.026 13.5 31.1 0.23 10.4 2.2 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2722) Pox_Ag35 PF03286.9 CDI74551.1 - 1.5 8.3 18.7 0.34 10.4 8.3 2.5 2 0 0 2 2 2 0 Pox virus Ag35 surface protein GOLD_2 PF13897.1 CDI74551.1 - 3.4 7.9 12.0 3.6 7.8 3.7 3.0 2 0 0 2 2 2 0 Golgi-dynamics membrane-trafficking RNA_pol_3_Rpc31 PF11705.3 CDI74551.1 - 7.1 6.4 22.4 0.68 9.8 9.8 2.5 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 Prothymosin PF03247.9 CDI74551.1 - 8.9 6.5 38.0 0.23 11.6 18.9 2.5 2 0 0 2 2 2 0 Prothymosin/parathymosin family Serinc PF03348.10 CDI74552.1 - 0.0018 17.0 1.8 0.0018 17.0 1.3 4.0 3 1 0 3 3 3 1 Serine incorporator (Serinc) DUF912 PF06024.7 CDI74552.1 - 0.13 12.3 0.0 0.13 12.3 0.0 5.3 4 2 0 4 4 4 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Ni_hydr_CYTB PF01292.15 CDI74552.1 - 0.27 10.6 1.4 7.5 5.8 0.1 3.3 2 1 0 3 3 3 0 Prokaryotic cytochrome b561 Papilloma_E5 PF03025.9 CDI74552.1 - 1.5 8.8 8.8 10 6.1 2.2 2.3 2 0 0 2 2 2 0 Papillomavirus E5 Herpes_UL87 PF03043.9 CDI74552.1 - 3.4 5.9 19.5 2.6 6.3 0.8 2.3 2 1 0 2 2 2 0 Herpesvirus UL87 family Bystin PF05291.6 CDI74553.1 - 4.3e-109 364.0 0.9 6.7e-109 363.4 0.6 1.2 1 0 0 1 1 1 1 Bystin Ribosomal_L36e PF01158.13 CDI74554.1 - 3.1e-36 123.2 4.9 4e-36 122.9 3.4 1.1 1 0 0 1 1 1 1 Ribosomal protein L36e Mitofilin PF09731.4 CDI74555.1 - 0.0035 16.0 37.7 0.067 11.8 9.1 2.4 2 0 0 2 2 2 2 Mitochondrial inner membrane protein HBS1_N PF08938.5 CDI74555.1 - 0.069 13.2 0.1 0.069 13.2 0.1 3.4 3 1 0 3 3 3 0 HBS1 N-terminus GAS PF13851.1 CDI74556.1 - 1.8 7.6 58.1 0.02 14.1 14.7 3.9 2 1 2 4 4 4 0 Growth-arrest specific micro-tubule binding DUF883 PF05957.8 CDI74557.1 - 0.063 13.6 2.8 0.079 13.3 2.0 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) DHHW PF14286.1 CDI74557.1 - 0.085 12.1 0.6 0.097 11.9 0.4 1.1 1 0 0 1 1 1 0 DHHW protein FbpA PF05833.6 CDI74557.1 - 0.12 10.8 14.6 0.14 10.6 10.1 1.0 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) RraB PF06877.6 CDI74557.1 - 0.15 12.7 5.9 0.18 12.4 4.1 1.1 1 0 0 1 1 1 0 Regulator of ribonuclease activity B DUF4355 PF14265.1 CDI74557.1 - 0.29 11.1 13.8 0.38 10.7 9.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4355) Pex14_N PF04695.8 CDI74557.1 - 0.29 11.1 10.2 0.38 10.8 7.0 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Cauli_AT PF03233.8 CDI74557.1 - 0.29 10.8 3.5 0.31 10.7 2.4 1.0 1 0 0 1 1 1 0 Aphid transmission protein 7tm_7 PF08395.7 CDI74557.1 - 0.46 9.4 15.7 0.54 9.2 10.9 1.0 1 0 0 1 1 1 0 7tm Chemosensory receptor TUDOR PF00567.19 CDI74557.1 - 0.66 9.8 9.5 3.6 7.4 3.4 2.0 1 1 1 2 2 2 0 Tudor domain Peptidase_S15 PF02129.13 CDI74557.1 - 0.71 9.2 6.3 0.7 9.2 4.3 1.0 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) PTPlike_phytase PF14566.1 CDI74557.1 - 0.86 9.6 5.1 0.9 9.5 3.6 1.1 1 0 0 1 1 1 0 Inositol hexakisphosphate DUF972 PF06156.8 CDI74557.1 - 0.89 9.9 12.9 1.1 9.6 9.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF972) DUF2813 PF11398.3 CDI74557.1 - 0.96 8.4 13.2 1.1 8.2 9.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2813) EIIBC-GUT_N PF03612.9 CDI74557.1 - 1.1 8.7 3.5 1.4 8.5 2.4 1.2 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus OATP PF03137.15 CDI74557.1 - 1.4 6.8 6.8 1.6 6.6 4.7 1.0 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family GvpL_GvpF PF06386.6 CDI74557.1 - 1.5 8.3 12.7 1.7 8.1 8.8 1.0 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF V_ATPase_I PF01496.14 CDI74557.1 - 1.6 6.5 9.4 1.6 6.5 6.5 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Cyclin_C PF02984.14 CDI74557.1 - 1.8 8.5 6.1 2.1 8.3 4.2 1.2 1 0 0 1 1 1 0 Cyclin, C-terminal domain Vps39_2 PF10367.4 CDI74557.1 - 2.1 8.5 9.5 2.4 8.3 6.6 1.1 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 2 LON PF02190.11 CDI74557.1 - 2.2 7.9 6.4 2.7 7.6 4.4 1.2 1 0 0 1 1 1 0 ATP-dependent protease La (LON) domain DUF4446 PF14584.1 CDI74557.1 - 2.3 8.0 10.4 2.7 7.8 7.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) DUF2203 PF09969.4 CDI74557.1 - 2.4 8.3 6.9 3.1 8.0 4.8 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) Peptidase_S46 PF10459.4 CDI74557.1 - 2.9 6.1 7.8 3.2 6.0 5.4 1.0 1 0 0 1 1 1 0 Peptidase S46 SecA_DEAD PF07517.9 CDI74557.1 - 3 7.0 10.4 4 6.6 7.2 1.2 1 0 0 1 1 1 0 SecA DEAD-like domain HI0933_like PF03486.9 CDI74557.1 - 4 5.8 9.0 4.1 5.7 6.3 1.0 1 0 0 1 1 1 0 HI0933-like protein Mgr1 PF08602.5 CDI74557.1 - 4 6.3 7.1 4.5 6.1 4.9 1.0 1 0 0 1 1 1 0 Mgr1-like, i-AAA protease complex subunit APG6 PF04111.7 CDI74557.1 - 4.1 6.3 16.6 4.5 6.2 11.5 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF4175 PF13779.1 CDI74557.1 - 4.2 4.9 31.4 4.7 4.7 21.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Med15 PF09606.5 CDI74557.1 - 4.3 5.4 45.0 4.7 5.2 31.2 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal FliP PF00813.15 CDI74557.1 - 4.4 6.9 8.4 5.1 6.7 5.8 1.0 1 0 0 1 1 1 0 FliP family Tweety PF04906.8 CDI74557.1 - 4.6 5.5 12.0 5.1 5.4 8.3 1.0 1 0 0 1 1 1 0 Tweety DOR PF14839.1 CDI74557.1 - 4.6 6.9 14.2 5 6.8 9.8 1.1 1 0 0 1 1 1 0 DOR family EMP24_GP25L PF01105.19 CDI74557.1 - 5.3 6.7 10.3 5.7 6.6 7.2 1.1 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD TFIIA PF03153.8 CDI74557.1 - 5.7 6.7 20.0 5.6 6.7 13.9 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF2232 PF09991.4 CDI74557.1 - 5.9 5.7 15.2 7.1 5.5 10.5 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) UPF0118 PF01594.11 CDI74557.1 - 6.2 5.7 6.9 6.4 5.6 4.8 1.0 1 0 0 1 1 1 0 Domain of unknown function DUF20 IPK PF03770.11 CDI74557.1 - 7 6.2 9.5 8.1 6.0 6.6 1.0 1 0 0 1 1 1 0 Inositol polyphosphate kinase Serinc PF03348.10 CDI74557.1 - 7.1 5.2 7.1 7.9 5.0 4.9 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) PRKCSH-like PF12999.2 CDI74557.1 - 7.1 6.1 8.6 8.4 5.9 6.0 1.0 1 0 0 1 1 1 0 Glucosidase II beta subunit-like DUF4557 PF15101.1 CDI74557.1 - 7.3 6.3 18.3 8.3 6.1 12.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) Ctr PF04145.10 CDI74557.1 - 7.3 6.6 6.1 8.2 6.4 4.2 1.1 1 0 0 1 1 1 0 Ctr copper transporter family DUF607 PF04678.8 CDI74557.1 - 8.2 6.3 9.8 9.4 6.1 6.8 1.1 1 0 0 1 1 1 0 Protein of unknown function, DUF607 Virul_fac_BrkB PF03631.10 CDI74557.1 - 9.1 5.5 7.5 10 5.4 5.2 1.1 1 0 0 1 1 1 0 Virulence factor BrkB Tho2 PF11262.3 CDI74557.1 - 9.4 5.1 10.6 10 5.0 7.3 1.0 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 PCEMA1 PF07418.6 CDI74558.1 - 0.017 14.4 6.1 0.023 14.0 4.2 1.2 1 0 0 1 1 1 0 Acidic phosphoprotein precursor PCEMA1 RNA_lig_T4_1 PF09511.5 CDI74558.1 - 0.031 13.7 3.5 0.037 13.4 2.4 1.1 1 0 0 1 1 1 0 RNA ligase PAT1 PF09770.4 CDI74558.1 - 0.48 8.6 58.5 0.6 8.2 40.5 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 FimP PF09766.4 CDI74558.1 - 0.72 8.8 36.5 0.065 12.3 5.3 2.1 2 0 0 2 2 2 0 Fms-interacting protein SeqA PF03925.8 CDI74558.1 - 1.4 8.5 15.0 0.77 9.4 0.3 2.2 2 0 0 2 2 2 0 SeqA protein PAP_RNA-bind PF04926.10 CDI74558.1 - 1.7 8.1 9.8 0.2 11.1 0.2 2.2 2 0 0 2 2 2 0 Poly(A) polymerase predicted RNA binding domain DUF1800 PF08811.6 CDI74558.1 - 1.8 7.3 29.2 2 7.2 10.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1800) DUF1764 PF08576.5 CDI74558.1 - 2.6 8.8 21.4 6 7.7 1.7 2.7 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF1764) Peptidase_S49_N PF08496.5 CDI74558.1 - 3.6 7.3 20.0 5.1 6.8 7.0 2.3 2 0 0 2 2 2 0 Peptidase family S49 N-terminal MCR_alpha PF02249.12 CDI74558.1 - 5 7.1 8.4 1.7 8.6 0.0 2.5 2 0 0 2 2 2 0 Methyl-coenzyme M reductase alpha subunit, C-terminal domain zf-DHHC PF01529.15 CDI74558.1 - 6.7 6.0 11.7 0.93 8.8 0.1 2.3 2 0 0 2 2 2 0 DHHC palmitoyltransferase SpoIIIAH PF12685.2 CDI74558.1 - 8.2 5.8 27.6 2.1 7.8 14.0 2.1 2 0 0 2 2 2 0 SpoIIIAH-like protein MIF4G_like_2 PF09090.6 CDI74559.1 - 4.1e-10 39.3 0.2 1.9e-09 37.1 0.0 2.0 2 0 0 2 2 2 1 MIF4G like MIF4G_like PF09088.6 CDI74559.1 - 0.18 11.2 0.2 0.58 9.5 0.0 2.0 2 1 0 2 2 2 0 MIF4G like TFIIA PF03153.8 CDI74559.1 - 4.1 7.2 13.0 2.4 7.9 2.6 2.3 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit IncA PF04156.9 CDI74560.1 - 0.0002 20.9 21.7 0.0002 20.9 15.0 4.0 3 1 0 3 3 3 1 IncA protein Rubis-subs-bind PF09273.6 CDI74561.1 - 0.025 14.4 1.1 0.047 13.6 0.1 1.8 2 0 0 2 2 2 0 Rubisco LSMT substrate-binding SR-25 PF10500.4 CDI74563.1 - 0.0012 18.3 19.3 0.0012 18.3 13.4 2.7 2 1 0 2 2 2 1 Nuclear RNA-splicing-associated protein Utp14 PF04615.8 CDI74563.1 - 0.02 13.0 18.8 0.026 12.7 13.0 1.1 1 0 0 1 1 1 0 Utp14 protein DUF1510 PF07423.6 CDI74563.1 - 3.4 6.9 20.9 3 7.1 12.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) DUF4544 PF15077.1 CDI74563.1 - 7.2 6.0 14.4 4.9 6.5 8.8 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4544) DUF243 PF03103.12 CDI74563.1 - 9.5 6.4 18.2 2.1 8.5 0.4 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF243) FHIPEP PF00771.15 CDI74563.1 - 9.7 4.3 12.8 23 3.1 8.9 1.6 1 1 0 1 1 1 0 FHIPEP family Med15 PF09606.5 CDI74564.1 - 0.01 14.0 70.9 0.011 13.9 49.2 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal CDC45 PF02724.9 CDI74564.1 - 0.016 13.2 18.2 0.022 12.7 12.6 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF605 PF04652.11 CDI74564.1 - 0.034 13.5 33.3 0.041 13.2 23.1 1.1 1 0 0 1 1 1 0 Vta1 like FAM60A PF15396.1 CDI74564.1 - 0.051 13.3 17.8 0.075 12.7 12.4 1.3 1 0 0 1 1 1 0 Protein Family FAM60A BTV_NS2 PF04514.7 CDI74564.1 - 0.082 11.7 14.4 0.092 11.6 10.0 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Peptidase_S15 PF02129.13 CDI74564.1 - 0.21 10.9 17.0 0.31 10.4 11.8 1.2 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) SOBP PF15279.1 CDI74564.1 - 0.21 11.9 21.8 0.25 11.7 15.1 1.0 1 0 0 1 1 1 0 Sine oculis-binding protein Ycf1 PF05758.7 CDI74564.1 - 0.22 9.1 16.8 0.23 9.1 11.6 1.0 1 0 0 1 1 1 0 Ycf1 XAP5 PF04921.9 CDI74564.1 - 0.38 10.2 15.0 0.48 9.9 10.4 1.1 1 0 0 1 1 1 0 XAP5, circadian clock regulator SAGA-Tad1 PF12767.2 CDI74564.1 - 0.41 10.2 27.6 0.52 9.9 19.1 1.1 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit Spc7_N PF15402.1 CDI74564.1 - 0.43 8.5 26.0 0.5 8.3 18.0 1.1 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 eIF-3_zeta PF05091.7 CDI74564.1 - 0.44 9.1 25.2 0.5 8.9 17.4 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) PAT1 PF09770.4 CDI74564.1 - 0.79 7.8 55.2 0.88 7.7 38.3 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Herpes_UL87 PF03043.9 CDI74564.1 - 1.2 7.4 13.6 1.1 7.5 9.4 1.1 1 0 0 1 1 1 0 Herpesvirus UL87 family Hid1 PF12722.2 CDI74564.1 - 2 5.9 23.5 2.2 5.8 16.3 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein GAGA_bind PF06217.7 CDI74564.1 - 2.5 7.9 20.8 3 7.7 14.4 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family Nop53 PF07767.6 CDI74564.1 - 2.7 6.8 30.5 3.2 6.6 21.2 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) DUF4045 PF13254.1 CDI74564.1 - 3 7.0 21.0 3.5 6.8 14.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Activator_LAG-3 PF11498.3 CDI74564.1 - 3.2 6.4 70.8 3.5 6.2 49.0 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Presenilin PF01080.12 CDI74564.1 - 3.4 6.3 20.7 4.5 6.0 14.4 1.2 1 0 0 1 1 1 0 Presenilin FAM217 PF15344.1 CDI74564.1 - 3.8 6.9 26.2 4.2 6.8 18.1 1.1 1 0 0 1 1 1 0 FAM217 family Peptidase_S64 PF08192.6 CDI74564.1 - 3.9 5.7 22.2 4.3 5.5 15.4 1.0 1 0 0 1 1 1 0 Peptidase family S64 Utp14 PF04615.8 CDI74564.1 - 4 5.4 28.1 4.5 5.3 19.5 1.0 1 0 0 1 1 1 0 Utp14 protein U1snRNP70_N PF12220.3 CDI74564.1 - 5.4 7.4 25.3 4.8 7.5 6.3 2.2 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal PRP1_N PF06424.7 CDI74564.1 - 5.8 7.2 19.7 7.8 6.8 13.7 1.2 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal Caldesmon PF02029.10 CDI74564.1 - 6.7 5.0 20.8 8.1 4.7 14.4 1.1 1 0 0 1 1 1 0 Caldesmon Neur_chan_memb PF02932.11 CDI74564.1 - 7.8 6.3 15.5 9.9 5.9 10.8 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF3474 PF11960.3 CDI74564.1 - 9.5 6.2 11.1 13 5.8 7.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3474) Asp-B-Hydro_N PF05279.6 CDI74564.1 - 9.5 5.9 16.4 13 5.5 11.4 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region OmpH PF03938.9 CDI74564.1 - 9.7 6.1 56.6 12 5.7 39.2 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Pex14_N PF04695.8 CDI74565.1 - 0.026 14.5 13.5 0.03 14.3 9.4 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF3604 PF12228.3 CDI74565.1 - 0.18 9.9 8.3 0.19 9.8 5.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3604) Gly-zipper_OmpA PF13436.1 CDI74565.1 - 0.23 11.0 15.6 0.27 10.8 10.8 1.1 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain Med15 PF09606.5 CDI74565.1 - 0.29 9.3 34.0 0.27 9.3 23.6 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Hist_deacetyl PF00850.14 CDI74565.1 - 0.46 9.7 4.1 0.54 9.5 2.9 1.0 1 0 0 1 1 1 0 Histone deacetylase domain DUF3371 PF11851.3 CDI74565.1 - 0.5 11.0 14.9 0.55 10.9 10.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3371) DUF4557 PF15101.1 CDI74565.1 - 0.7 9.7 20.6 0.7 9.6 14.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) PsbW PF07123.7 CDI74565.1 - 0.71 9.9 9.0 0.86 9.6 6.3 1.2 1 0 0 1 1 1 0 Photosystem II reaction centre W protein (PsbW) Prp31_C PF09785.4 CDI74565.1 - 0.8 10.1 10.6 0.9 9.9 7.4 1.1 1 0 0 1 1 1 0 Prp31 C terminal domain RED_N PF07808.8 CDI74565.1 - 0.84 8.8 14.1 0.86 8.7 9.8 1.1 1 0 0 1 1 1 0 RED-like protein N-terminal region DUF2052 PF09747.4 CDI74565.1 - 0.85 9.5 11.4 0.87 9.4 7.9 1.0 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) Vps39_1 PF10366.4 CDI74565.1 - 0.92 9.5 7.5 1.2 9.2 5.2 1.1 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 1 FCP1_C PF09309.5 CDI74565.1 - 0.93 8.7 10.1 1 8.6 7.0 1.2 1 0 0 1 1 1 0 FCP1, C-terminal Rxt3 PF08642.5 CDI74565.1 - 1.1 9.5 3.9 1.3 9.3 2.7 1.2 1 0 0 1 1 1 0 Histone deacetylation protein Rxt3 CemA PF03040.9 CDI74565.1 - 1.1 8.7 4.9 1.1 8.8 3.4 1.0 1 0 0 1 1 1 0 CemA family Activator_LAG-3 PF11498.3 CDI74565.1 - 1.1 7.8 39.8 1.2 7.7 27.6 1.0 1 0 0 1 1 1 0 Transcriptional activator LAG-3 HD-ZIP_N PF04618.7 CDI74565.1 - 1.2 9.7 5.0 1.4 9.5 3.5 1.1 1 0 0 1 1 1 0 HD-ZIP protein N terminus Bud13 PF09736.4 CDI74565.1 - 1.2 9.3 13.1 1.3 9.2 9.1 1.1 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex Ctr PF04145.10 CDI74565.1 - 1.3 9.0 7.9 1.5 8.8 5.4 1.1 1 0 0 1 1 1 0 Ctr copper transporter family Ribosomal_60s PF00428.14 CDI74565.1 - 1.3 9.4 9.1 1.5 9.2 6.3 1.2 1 0 0 1 1 1 0 60s Acidic ribosomal protein NifQ PF04891.7 CDI74565.1 - 1.5 8.9 9.4 1.5 8.9 6.5 1.1 1 0 0 1 1 1 0 NifQ DUF4512 PF14975.1 CDI74565.1 - 1.5 9.7 5.1 1.6 9.6 3.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4512) Band_3_cyto PF07565.8 CDI74565.1 - 1.5 8.3 10.2 1.5 8.3 7.0 1.0 1 0 0 1 1 1 0 Band 3 cytoplasmic domain BRF1 PF07741.8 CDI74565.1 - 1.5 9.0 14.0 1.9 8.7 9.7 1.2 1 0 0 1 1 1 0 Brf1-like TBP-binding domain FimP PF09766.4 CDI74565.1 - 1.6 7.7 18.5 1.8 7.5 12.8 1.0 1 0 0 1 1 1 0 Fms-interacting protein DUF2232 PF09991.4 CDI74565.1 - 1.9 7.4 6.0 2.1 7.2 4.2 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) DUF4175 PF13779.1 CDI74565.1 - 1.9 6.1 28.4 1.9 6.0 19.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) FAM60A PF15396.1 CDI74565.1 - 2 8.1 6.4 2.1 8.0 4.5 1.0 1 0 0 1 1 1 0 Protein Family FAM60A Pex16 PF08610.5 CDI74565.1 - 2 7.3 7.7 1.8 7.4 5.3 1.0 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) DUF4647 PF15504.1 CDI74565.1 - 2.1 7.0 12.1 2.2 7.0 8.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4647) DUF912 PF06024.7 CDI74565.1 - 2.1 8.4 5.7 2.5 8.2 3.9 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Gti1_Pac2 PF09729.4 CDI74565.1 - 2.3 8.0 5.8 2.5 7.9 4.0 1.1 1 0 0 1 1 1 0 Gti1/Pac2 family DUF1764 PF08576.5 CDI74565.1 - 2.6 8.8 10.1 3.1 8.6 7.0 1.2 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) Mgr1 PF08602.5 CDI74565.1 - 2.6 6.9 6.2 3 6.7 4.3 1.0 1 0 0 1 1 1 0 Mgr1-like, i-AAA protease complex subunit Hid1 PF12722.2 CDI74565.1 - 2.9 5.4 9.4 3.1 5.3 6.5 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein ATAD4 PF15321.1 CDI74565.1 - 3.3 8.7 7.1 4.1 8.4 4.9 1.3 1 0 0 1 1 1 0 ATPase family AAA domain containing 4 DUF966 PF06136.8 CDI74565.1 - 3.4 6.9 9.8 3.7 6.8 6.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF966) DUF3533 PF12051.3 CDI74565.1 - 3.4 6.2 11.5 3.8 6.1 8.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3533) DUF1448 PF07289.6 CDI74565.1 - 3.8 6.3 7.8 4 6.2 5.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1448) ABC2_membrane_2 PF12679.2 CDI74565.1 - 3.9 6.2 5.1 4.5 6.0 3.5 1.0 1 0 0 1 1 1 0 ABC-2 family transporter protein GPCR_chapero_1 PF11904.3 CDI74565.1 - 4.3 6.3 8.6 4.7 6.2 5.9 1.0 1 0 0 1 1 1 0 GPCR-chaperone Baculo_PP31 PF05311.6 CDI74565.1 - 4.4 6.5 10.0 4.4 6.4 6.9 1.0 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) PIH1 PF08190.7 CDI74565.1 - 4.4 6.6 16.7 4.4 6.6 11.6 1.0 1 0 0 1 1 1 0 pre-RNA processing PIH1/Nop17 Peptidase_U57 PF05582.7 CDI74565.1 - 4.5 6.1 7.7 4.8 6.0 5.4 1.0 1 0 0 1 1 1 0 YabG peptidase U57 Hom_end_hint PF05203.11 CDI74565.1 - 4.7 6.8 6.0 5.1 6.7 4.2 1.1 1 0 0 1 1 1 0 Hom_end-associated Hint Glyco_transf_15 PF01793.11 CDI74565.1 - 4.8 6.0 9.5 5 5.9 6.6 1.0 1 0 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase DUF702 PF05142.7 CDI74565.1 - 4.8 7.3 12.2 4.9 7.2 8.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF702) Suf PF05843.9 CDI74565.1 - 4.9 6.7 14.9 5 6.7 10.3 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) F-protein PF00469.15 CDI74565.1 - 5.4 6.3 9.4 5.3 6.3 6.5 1.0 1 0 0 1 1 1 0 Negative factor, (F-Protein) or Nef PAT1 PF09770.4 CDI74565.1 - 5.4 5.1 27.2 5.3 5.1 18.8 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DDHD PF02862.12 CDI74565.1 - 5.7 6.6 9.1 6 6.5 6.3 1.0 1 0 0 1 1 1 0 DDHD domain Rpp20 PF12328.3 CDI74565.1 - 6 6.5 9.8 6.8 6.3 6.8 1.1 1 0 0 1 1 1 0 Rpp20 subunit of nuclear RNase MRP and P TMEM51 PF15345.1 CDI74565.1 - 6.1 6.4 12.3 6.6 6.3 8.5 1.1 1 0 0 1 1 1 0 Transmembrane protein 51 Herpes_glycop PF01528.11 CDI74565.1 - 6.5 5.3 6.0 7.2 5.1 4.2 1.1 1 0 0 1 1 1 0 Herpesvirus glycoprotein M TFIIA PF03153.8 CDI74565.1 - 6.6 6.5 21.7 6.5 6.5 15.0 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PXA PF02194.10 CDI74565.1 - 6.6 6.2 8.3 6.7 6.2 5.8 1.0 1 0 0 1 1 1 0 PXA domain TraV PF09676.5 CDI74565.1 - 6.8 7.4 12.9 7.3 7.3 9.0 1.1 1 0 0 1 1 1 0 Type IV conjugative transfer system lipoprotein (TraV) EPL1 PF10513.4 CDI74565.1 - 6.9 6.9 10.8 6.7 6.9 7.5 1.1 1 0 0 1 1 1 0 Enhancer of polycomb-like AUX_IAA PF02309.11 CDI74565.1 - 7.8 6.1 8.2 8.4 6.0 5.7 1.1 1 0 0 1 1 1 0 AUX/IAA family DUF2324 PF10086.4 CDI74565.1 - 8.2 5.5 7.0 9.7 5.3 4.9 1.2 1 0 0 1 1 1 0 Putative membrane peptidase family (DUF2324) DUF3306 PF11748.3 CDI74565.1 - 9.4 6.9 14.8 12 6.5 10.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3306) OmpH PF03938.9 CDI74565.1 - 9.4 6.1 30.4 11 5.9 21.1 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF3675 PF12428.3 CDI74565.1 - 9.8 6.4 6.4 12 6.2 4.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3675) Mak10 PF04112.8 CDI74566.1 - 0.25 10.5 0.0 0.25 10.5 0.0 3.0 4 1 0 4 4 4 0 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase SR-25 PF10500.4 CDI74567.1 - 0.007 15.8 20.8 0.007 15.8 14.4 3.8 3 1 1 4 4 4 2 Nuclear RNA-splicing-associated protein DUF4207 PF13904.1 CDI74567.1 - 0.0088 15.4 22.6 0.0088 15.4 15.6 3.9 2 1 0 2 2 2 1 Domain of unknown function (DUF4207) RAP1 PF07218.6 CDI74567.1 - 1.1 7.3 15.3 1.5 6.8 10.6 1.3 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) PAT1 PF09770.4 CDI74567.1 - 3.9 5.6 74.2 1.5 6.9 30.1 2.2 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 Kinesin PF00225.18 CDI74568.1 - 1.1e-10 40.7 0.0 1.1e-10 40.7 0.0 2.6 2 1 1 3 3 3 2 Kinesin motor domain TFIIA PF03153.8 CDI74569.1 - 0.0014 18.5 49.9 0.0018 18.2 34.6 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Med15 PF09606.5 CDI74569.1 - 0.0074 14.5 60.3 0.0083 14.3 41.8 1.1 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal PAT1 PF09770.4 CDI74569.1 - 0.051 11.8 50.8 0.062 11.5 35.2 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF4175 PF13779.1 CDI74569.1 - 0.54 7.8 51.6 0.76 7.3 35.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) SOBP PF15279.1 CDI74569.1 - 1.2 9.4 39.3 1.6 9.0 27.3 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein Utp14 PF04615.8 CDI74569.1 - 1.8 6.6 45.4 3 5.8 31.4 1.4 1 0 0 1 1 1 0 Utp14 protein GAGA_bind PF06217.7 CDI74569.1 - 1.8 8.4 29.8 3.1 7.7 20.7 1.4 1 0 0 1 1 1 0 GAGA binding protein-like family eIF-3_zeta PF05091.7 CDI74569.1 - 1.9 7.0 31.5 2.4 6.7 21.9 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) HemX PF04375.9 CDI74569.1 - 3.2 6.2 40.3 4.6 5.7 27.9 1.2 1 0 0 1 1 1 0 HemX Ycf1 PF05758.7 CDI74569.1 - 3.7 5.1 24.9 4.7 4.7 17.3 1.2 1 0 0 1 1 1 0 Ycf1 Dicty_REP PF05086.7 CDI74569.1 - 4.2 5.0 35.8 5.4 4.6 24.8 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Asp-B-Hydro_N PF05279.6 CDI74569.1 - 5.4 6.7 21.5 0.97 9.2 12.4 1.7 2 0 0 2 2 2 0 Aspartyl beta-hydroxylase N-terminal region AvrE PF11725.3 CDI74569.1 - 6 3.7 39.7 6.8 3.5 27.5 1.0 1 0 0 1 1 1 0 Pathogenicity factor Serinc PF03348.10 CDI74569.1 - 7.4 5.1 25.5 12 4.4 17.7 1.5 1 0 0 1 1 1 0 Serine incorporator (Serinc) Hom_end_hint PF05203.11 CDI74570.1 - 0.08 12.6 0.0 0.08 12.6 0.0 6.1 5 1 0 6 6 6 0 Hom_end-associated Hint Mem_trans PF03547.13 CDI74570.1 - 0.84 7.8 0.0 0.84 7.8 0.0 5.1 5 0 0 5 5 5 0 Membrane transport protein Yae1_N PF09811.4 CDI74571.1 - 0.0022 17.4 0.6 3.1 7.3 0.4 3.5 1 1 0 1 1 1 1 Essential protein Yae1, N terminal SR-25 PF10500.4 CDI74572.1 - 0.013 14.9 16.2 0.013 14.9 11.3 2.8 2 1 0 2 2 2 0 Nuclear RNA-splicing-associated protein Ribosomal_60s PF00428.14 CDI74572.1 - 0.021 15.2 9.1 0.021 15.2 6.3 1.8 2 0 0 2 2 2 0 60s Acidic ribosomal protein MIP-T3 PF10243.4 CDI74572.1 - 0.036 12.5 30.9 0.049 12.1 21.4 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DUF732 PF05305.9 CDI74572.1 - 0.099 12.7 7.0 0.32 11.0 4.9 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF732) DUF572 PF04502.8 CDI74572.1 - 2.1 7.5 36.9 3 6.9 25.6 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) RNF111_N PF15303.1 CDI74572.1 - 2.4 7.6 57.6 31 3.9 39.9 2.2 1 1 0 1 1 1 0 E3 ubiquitin-protein ligase Arkadia N-terminus AF-4 PF05110.8 CDI74572.1 - 5.2 4.8 48.4 1.2 6.8 17.1 2.1 2 0 0 2 2 2 0 AF-4 proto-oncoprotein DUF508 PF04370.7 CDI74572.1 - 5.3 6.6 20.3 0.28 10.8 2.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF508) DUF1510 PF07423.6 CDI74573.1 - 0.00014 21.3 37.3 0.00017 21.0 25.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) Neur_chan_memb PF02932.11 CDI74573.1 - 1.2 8.9 27.1 1.3 8.8 18.8 1.0 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Herpes_DNAp_acc PF04929.7 CDI74573.1 - 5.9 5.7 29.1 7.5 5.4 20.2 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor CTP_transf_3 PF02348.14 CDI74574.1 - 2.8 7.5 10.0 0.31 10.6 1.7 2.2 2 0 0 2 2 2 0 Cytidylyltransferase LAB_N PF07578.6 CDI74575.1 - 0.21 11.5 0.7 65 3.5 0.1 3.4 3 0 0 3 3 3 0 Lipid A Biosynthesis N-terminal domain Hydrolase_3 PF08282.7 CDI74576.1 - 1e-42 146.5 0.0 2.1e-39 135.6 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.8 CDI74576.1 - 9.6e-13 47.9 0.0 4e-07 29.5 0.0 2.1 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase Hydrolase PF00702.21 CDI74576.1 - 5e-05 23.8 0.0 0.00075 19.9 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Trehalose_PPase PF02358.11 CDI74576.1 - 0.0016 17.3 0.0 0.0036 16.2 0.0 1.6 1 1 0 1 1 1 1 Trehalose-phosphatase AMH_N PF04709.7 CDI74576.1 - 0.0035 16.3 0.0 0.0053 15.7 0.0 1.2 1 0 0 1 1 1 1 Anti-Mullerian hormone, N terminal region HAD PF12710.2 CDI74576.1 - 0.018 15.2 0.0 0.31 11.1 0.0 2.4 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.1 CDI74576.1 - 0.11 12.4 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase DNA_pol_viral_N PF00242.12 CDI74577.1 - 0.078 11.9 25.8 0.089 11.8 17.9 1.0 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain DUF572 PF04502.8 CDI74577.1 - 0.22 10.7 21.9 0.26 10.4 15.2 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF2217 PF10265.4 CDI74577.1 - 0.22 10.2 21.4 0.26 10.0 14.9 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) Ashwin PF15323.1 CDI74577.1 - 0.23 11.4 20.6 0.27 11.2 14.3 1.1 1 0 0 1 1 1 0 Developmental protein NABP PF07990.7 CDI74577.1 - 0.33 10.1 24.8 0.39 9.9 17.2 1.0 1 0 0 1 1 1 0 Nucleic acid binding protein NABP Macoilin PF09726.4 CDI74577.1 - 0.58 8.3 29.8 0.84 7.8 20.6 1.2 1 0 0 1 1 1 0 Transmembrane protein PAT1 PF09770.4 CDI74577.1 - 0.72 8.0 30.3 0.88 7.7 21.0 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF936 PF06075.7 CDI74577.1 - 1.3 7.8 22.8 1.5 7.6 15.8 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) SLD3 PF08639.5 CDI74577.1 - 1.4 7.4 28.1 1.6 7.2 19.5 1.1 1 0 0 1 1 1 0 DNA replication regulator SLD3 Utp14 PF04615.8 CDI74577.1 - 1.5 6.8 23.6 1.8 6.6 16.3 1.0 1 0 0 1 1 1 0 Utp14 protein Pex16 PF08610.5 CDI74577.1 - 1.6 7.6 14.8 2.1 7.2 10.3 1.2 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) Ndc1_Nup PF09531.5 CDI74577.1 - 1.7 6.9 21.0 2 6.7 14.5 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup IER PF05760.7 CDI74577.1 - 1.9 8.3 26.3 2.5 7.9 18.3 1.1 1 0 0 1 1 1 0 Immediate early response protein (IER) DUF4175 PF13779.1 CDI74577.1 - 2.4 5.7 29.3 3 5.4 20.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Neur_chan_memb PF02932.11 CDI74577.1 - 2.6 7.8 17.2 3.3 7.5 11.9 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Mcm10 PF09332.6 CDI74577.1 - 2.6 7.3 23.1 3.1 7.0 16.0 1.1 1 0 0 1 1 1 0 Mcm10 replication factor Hid1 PF12722.2 CDI74577.1 - 2.8 5.4 26.3 3.5 5.1 18.2 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SRP-alpha_N PF04086.8 CDI74577.1 - 3.1 7.1 23.4 3.8 6.8 16.2 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal CCDC84 PF14968.1 CDI74577.1 - 3.2 7.1 22.8 4 6.8 15.8 1.0 1 0 0 1 1 1 0 Coiled coil protein 84 PGA2 PF07543.7 CDI74577.1 - 4.2 7.1 10.3 7 6.4 1.7 2.2 2 0 0 2 2 2 0 Protein trafficking PGA2 MAP65_ASE1 PF03999.7 CDI74577.1 - 4.6 5.7 23.9 5.5 5.4 16.6 1.0 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) GPCR_chapero_1 PF11904.3 CDI74577.1 - 4.7 6.2 16.9 6.5 5.7 11.7 1.2 1 0 0 1 1 1 0 GPCR-chaperone DUF1675 PF07897.6 CDI74577.1 - 6.8 6.4 25.8 8 6.2 17.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) DUF1510 PF07423.6 CDI74577.1 - 7.3 5.8 23.7 10 5.4 16.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DUF1681 PF07933.9 CDI74577.1 - 8 5.9 9.6 1.7 8.1 3.9 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1681) CDC45 PF02724.9 CDI74577.1 - 8 4.3 17.9 12 3.7 12.4 1.3 1 0 0 1 1 1 0 CDC45-like protein Spc7_N PF15402.1 CDI74577.1 - 8.8 4.1 28.2 10 4.0 19.5 1.0 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 TFIIA PF03153.8 CDI74577.1 - 9 6.0 36.9 11 5.8 25.5 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PE_PPE_C PF12484.3 CDI74578.1 - 0.011 16.6 15.6 0.51 11.3 2.0 2.2 2 0 0 2 2 2 0 Polymorphic PE/PPE proteins C terminal DUF1764 PF08576.5 CDI74578.1 - 0.027 15.2 7.0 0.52 11.1 0.8 2.4 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF1764) Draxin PF15550.1 CDI74578.1 - 0.24 11.0 11.6 0.34 10.5 8.0 1.3 1 0 0 1 1 1 0 Draxin DUF1972 PF09314.6 CDI74578.1 - 0.26 10.7 1.2 0.52 9.7 0.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1972) PAT1 PF09770.4 CDI74578.1 - 2.3 6.3 43.6 3 5.9 30.2 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 FimP PF09766.4 CDI74578.1 - 3 6.8 24.3 0.93 8.4 7.0 2.1 2 0 0 2 2 2 0 Fms-interacting protein DUF2203 PF09969.4 CDI74578.1 - 3.6 7.8 10.3 0.63 10.2 1.7 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) Ofd1_CTDD PF10637.4 CDI74578.1 - 4.4 6.3 9.9 0.82 8.7 2.3 2.1 2 0 0 2 2 2 0 Oxoglutarate and iron-dependent oxygenase degradation C-term Pex16 PF08610.5 CDI74578.1 - 5.1 5.9 12.8 1.3 7.9 4.6 2.1 2 0 0 2 2 2 0 Peroxisomal membrane protein (Pex16) SeqA PF03925.8 CDI74578.1 - 5.6 6.6 11.3 1.4 8.5 2.0 2.2 2 0 0 2 2 2 0 SeqA protein DUF4484 PF14831.1 CDI74578.1 - 9.4 6.3 13.4 3.8 7.5 3.8 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4484) Pkinase PF00069.20 CDI74581.1 - 7.3e-25 87.5 42.4 8.8e-17 61.1 19.5 5.1 3 1 1 4 4 4 3 Protein kinase domain Pkinase_Tyr PF07714.12 CDI74581.1 - 7.5e-17 61.2 0.9 7.5e-17 61.2 0.6 3.8 2 1 2 4 4 4 2 Protein tyrosine kinase CDC45 PF02724.9 CDI74581.1 - 6.1e-06 24.5 14.5 6.1e-06 24.5 10.1 3.1 2 1 0 2 2 2 1 CDC45-like protein Exonuc_VII_L PF02601.10 CDI74581.1 - 0.066 12.4 39.8 0.031 13.4 12.9 2.5 2 0 0 2 2 2 0 Exonuclease VII, large subunit Suf PF05843.9 CDI74581.1 - 0.19 11.4 78.8 0.35 10.5 6.0 3.5 4 0 0 4 4 4 0 Suppressor of forked protein (Suf) RNA_pol_Rpb1_5 PF04998.12 CDI74581.1 - 0.3 10.2 28.1 1.1 8.4 3.1 2.2 2 0 0 2 2 2 0 RNA polymerase Rpb1, domain 5 FAM176 PF14851.1 CDI74582.1 - 0.67 9.6 4.8 1 9.0 3.3 1.3 1 0 0 1 1 1 0 FAM176 family DUF3866 PF12982.2 CDI74582.1 - 0.88 8.4 7.2 1 8.2 5.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3866) Inhibitor_I71 PF12628.2 CDI74582.1 - 1 9.0 7.8 1.3 8.7 5.4 1.1 1 0 0 1 1 1 0 Falstatin, cysteine peptidase inhibitor NAD_synthase PF02540.12 CDI74582.1 - 1.4 7.7 9.6 1.6 7.5 6.7 1.2 1 0 0 1 1 1 0 NAD synthase 5_nucleotid PF05761.9 CDI74582.1 - 1.7 7.0 18.3 1.9 6.8 12.7 1.0 1 0 0 1 1 1 0 5' nucleotidase family AIP3 PF03915.8 CDI74582.1 - 1.8 7.3 24.0 2 7.2 16.6 1.0 1 0 0 1 1 1 0 Actin interacting protein 3 2OG-FeII_Oxy_5 PF13759.1 CDI74582.1 - 1.8 8.8 8.7 1.9 8.8 5.3 1.5 1 1 1 2 2 2 0 Putative 2OG-Fe(II) oxygenase Plasmodium_Vir PF05795.6 CDI74582.1 - 1.9 7.6 7.2 2.2 7.3 5.0 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein DUF342 PF03961.8 CDI74582.1 - 1.9 6.7 24.4 2.2 6.5 16.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) V_ATPase_I PF01496.14 CDI74582.1 - 2.6 5.7 18.2 2.9 5.6 12.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Neur_chan_memb PF02932.11 CDI74582.1 - 2.8 7.7 14.2 3.2 7.5 9.8 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region PigN PF04987.9 CDI74582.1 - 3.5 6.1 5.8 4.1 5.9 4.0 1.3 1 0 0 1 1 1 0 Phosphatidylinositolglycan class N (PIG-N) DUF1741 PF08427.5 CDI74582.1 - 4.5 6.6 14.3 4.9 6.5 9.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1741) CPSF100_C PF13299.1 CDI74582.1 - 5.8 7.0 15.1 8.2 6.5 10.5 1.3 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal ARD PF03079.9 CDI74582.1 - 6 6.7 11.4 7.5 6.4 7.9 1.2 1 0 0 1 1 1 0 ARD/ARD' family Pox_RNA_Pol_19 PF05320.7 CDI74582.1 - 7.5 6.2 12.6 4.1 7.1 7.6 1.4 1 1 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit DUF4175 PF13779.1 CDI74582.1 - 7.7 4.0 57.7 9 3.8 40.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Hom_end_hint PF05203.11 CDI74582.1 - 8 6.1 16.2 9.5 5.8 11.2 1.1 1 0 0 1 1 1 0 Hom_end-associated Hint DUF3801 PF12687.2 CDI74583.1 - 0.0021 17.6 6.2 0.0021 17.6 4.3 8.3 5 3 0 5 5 5 2 Protein of unknown function (DUF3801) Thioredoxin PF00085.15 CDI74584.1 - 8.8e-56 186.0 0.8 3.9e-31 106.8 0.2 2.4 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_8 PF13905.1 CDI74584.1 - 6.2e-11 42.2 0.2 0.0037 17.3 0.0 4.1 2 2 2 4 4 4 2 Thioredoxin-like Thioredoxin_7 PF13899.1 CDI74584.1 - 9.2e-10 38.4 0.2 0.0004 20.3 0.0 2.8 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_6 PF13848.1 CDI74584.1 - 8.9e-09 35.4 0.0 0.0048 16.7 0.0 3.3 3 0 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_3 PF13192.1 CDI74584.1 - 9.5e-09 34.9 0.2 0.0019 17.9 0.0 2.9 3 0 0 3 3 3 2 Thioredoxin domain Thioredoxin_2 PF13098.1 CDI74584.1 - 5.6e-08 32.9 7.4 0.0077 16.4 0.1 4.6 3 2 0 3 3 3 2 Thioredoxin-like domain AhpC-TSA PF00578.16 CDI74584.1 - 6.2e-05 22.6 0.3 0.14 11.8 0.0 2.6 2 0 0 2 2 2 2 AhpC/TSA family Redoxin PF08534.5 CDI74584.1 - 0.00041 19.9 0.1 0.37 10.3 0.0 2.4 2 0 0 2 2 2 2 Redoxin Thioredoxin_9 PF14595.1 CDI74584.1 - 0.0037 16.8 11.4 0.086 12.4 0.0 3.5 4 0 0 4 4 4 2 Thioredoxin HyaE PF07449.6 CDI74584.1 - 0.0085 15.9 0.0 1.3 8.9 0.0 2.5 2 0 0 2 2 2 1 Hydrogenase-1 expression protein HyaE MsyB PF13984.1 CDI74584.1 - 0.019 15.0 0.0 0.019 15.0 0.0 2.9 4 0 0 4 4 2 0 MsyB protein DUF1840 PF08895.6 CDI74584.1 - 2.1 8.4 12.2 1.3 9.0 0.5 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1840) DUF4175 PF13779.1 CDI74584.1 - 2.8 5.5 28.4 0.099 10.3 7.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4175) OmpH PF03938.9 CDI74584.1 - 8.3 6.3 25.7 3.8 7.4 1.8 2.4 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Trypan_PARP PF05887.6 CDI74585.1 - 0.041 13.6 24.1 0.11 12.3 16.7 1.8 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Pex2_Pex12 PF04757.9 CDI74586.1 - 2.3e-06 27.2 0.1 2.3e-06 27.2 0.1 1.9 2 0 0 2 2 2 1 Pex2 / Pex12 amino terminal region Pex14_N PF04695.8 CDI74586.1 - 0.0043 17.0 14.1 0.0043 17.0 9.7 3.8 3 1 0 4 4 4 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Ribosomal_60s PF00428.14 CDI74586.1 - 0.012 16.0 7.2 0.012 16.0 5.0 6.1 5 2 1 6 6 4 0 60s Acidic ribosomal protein Spt20 PF12090.3 CDI74586.1 - 0.033 13.5 6.6 0.013 14.8 2.2 2.1 2 0 0 2 2 2 0 Spt20 family FLO_LFY PF01698.11 CDI74586.1 - 0.033 13.0 8.6 0.059 12.2 5.9 1.4 1 0 0 1 1 1 0 Floricaula / Leafy protein Ycf1 PF05758.7 CDI74586.1 - 0.036 11.7 0.1 0.038 11.7 0.0 1.1 1 0 0 1 1 1 0 Ycf1 RR_TM4-6 PF06459.7 CDI74586.1 - 0.1 12.4 9.8 0.22 11.3 6.8 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Spore_coat_CotO PF14153.1 CDI74586.1 - 0.25 10.7 13.6 0.56 9.6 9.4 1.5 1 0 0 1 1 1 0 Spore coat protein CotO FimP PF09766.4 CDI74586.1 - 1.1 8.2 19.0 2 7.3 13.2 1.4 1 0 0 1 1 1 0 Fms-interacting protein Suf PF05843.9 CDI74586.1 - 1.6 8.4 19.3 0.014 15.1 6.0 2.3 2 1 0 2 2 2 0 Suppressor of forked protein (Suf) Serinc PF03348.10 CDI74586.1 - 1.9 7.1 6.8 3.5 6.2 4.7 1.4 1 0 0 1 1 1 0 Serine incorporator (Serinc) SR-25 PF10500.4 CDI74586.1 - 3 7.2 38.0 2.6 7.4 5.2 3.4 3 0 0 3 3 3 0 Nuclear RNA-splicing-associated protein AIF_C PF14721.1 CDI74586.1 - 3.3 7.9 9.9 1.3 9.2 4.6 2.1 2 0 0 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Hid1 PF12722.2 CDI74586.1 - 3.5 5.2 9.4 1.7 6.2 3.8 2.0 2 0 0 2 2 2 0 High-temperature-induced dauer-formation protein Gag_spuma PF03276.9 CDI74586.1 - 4.3 5.5 21.8 11 4.2 15.1 1.6 1 0 0 1 1 1 0 Spumavirus gag protein DUF1510 PF07423.6 CDI74586.1 - 5.8 6.2 15.8 0.9 8.8 8.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) ERF PF04404.7 CDI74586.1 - 7.1 6.1 19.2 15 5.1 13.3 1.6 1 0 0 1 1 1 0 ERF superfamily Presenilin PF01080.12 CDI74586.1 - 7.8 5.2 11.5 0.23 10.2 1.5 2.2 2 0 0 2 2 2 0 Presenilin FAM60A PF15396.1 CDI74586.1 - 7.9 6.1 14.8 0.7 9.5 2.6 3.0 3 0 0 3 3 3 0 Protein Family FAM60A Pox_A11 PF05061.8 CDI74587.1 - 6.2 5.7 9.2 1.6 7.7 3.1 2.2 2 0 0 2 2 2 0 Poxvirus A11 Protein GMC_oxred_C PF05199.8 CDI74588.1 - 1.3e-20 74.1 0.0 1.3e-15 57.9 0.0 2.5 2 0 0 2 2 2 2 GMC oxidoreductase GMC_oxred_N PF00732.14 CDI74588.1 - 5.5e-08 32.3 0.4 8e-07 28.4 0.1 2.2 2 0 0 2 2 2 1 GMC oxidoreductase SIR2 PF02146.12 CDI74590.1 - 1.8e-45 154.8 0.0 2.3e-45 154.4 0.0 1.1 1 0 0 1 1 1 1 Sir2 family TPP_enzyme_M PF00205.17 CDI74590.1 - 2.5e-07 30.5 0.0 7.9e-05 22.4 0.0 2.2 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, central domain PNTB PF02233.11 CDI74590.1 - 0.083 11.6 0.0 1.5 7.5 0.0 2.0 2 0 0 2 2 2 0 NAD(P) transhydrogenase beta subunit Ras PF00071.17 CDI74591.1 - 7.2e-57 191.2 0.3 8.3e-57 191.0 0.2 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CDI74591.1 - 3.4e-19 69.4 0.0 5.4e-19 68.8 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CDI74591.1 - 4.1e-13 48.9 0.0 5.1e-13 48.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 CDI74591.1 - 7.1e-08 32.4 0.0 9.7e-08 31.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 CDI74591.1 - 2.3e-07 30.2 0.1 3.4e-07 29.6 0.1 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 CDI74591.1 - 2.2e-06 27.2 0.0 7.8e-05 22.1 0.0 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 CDI74591.1 - 0.00083 18.6 0.0 0.0012 18.0 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Arch_ATPase PF01637.13 CDI74591.1 - 0.0027 17.4 0.9 0.013 15.1 0.6 2.0 1 1 0 1 1 1 1 Archaeal ATPase Septin PF00735.13 CDI74591.1 - 0.011 14.7 0.1 0.02 13.9 0.1 1.4 1 0 0 1 1 1 0 Septin FeoB_N PF02421.13 CDI74591.1 - 0.012 14.9 0.1 0.22 10.7 0.1 2.4 2 1 1 3 3 3 0 Ferrous iron transport protein B AAA_22 PF13401.1 CDI74591.1 - 0.018 15.1 0.0 0.042 13.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain DUF258 PF03193.11 CDI74591.1 - 0.021 14.0 0.8 0.071 12.2 0.1 2.0 2 1 0 2 2 2 0 Protein of unknown function, DUF258 MobB PF03205.9 CDI74591.1 - 0.023 14.4 0.1 0.061 13.0 0.0 1.7 1 1 1 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.1 CDI74591.1 - 0.045 13.7 0.0 0.37 10.7 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain PduV-EutP PF10662.4 CDI74591.1 - 0.064 12.7 0.3 0.12 11.8 0.1 1.8 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF1581 PF07619.6 CDI74593.1 - 4.5 7.3 9.5 16 5.5 0.8 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1581) PQQ_2 PF13360.1 CDI74594.1 - 2e-07 30.7 27.8 0.00053 19.5 8.2 3.6 3 1 0 3 3 3 2 PQQ-like domain PQQ PF01011.16 CDI74594.1 - 0.004 16.6 0.0 1.7 8.3 0.1 3.4 4 0 0 4 4 4 2 PQQ enzyme repeat Claudin_2 PF13903.1 CDI74595.1 - 0.0066 16.1 7.7 0.01 15.5 5.4 1.4 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction DUF755 PF05501.6 CDI74595.1 - 3.8 7.6 18.9 0.3 11.1 6.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF755) Corona_nucleoca PF00937.13 CDI74595.1 - 9.7 5.0 9.5 11 4.8 6.6 1.3 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein Med15 PF09606.5 CDI74596.1 - 0.0026 16.0 35.6 0.0032 15.7 24.7 1.1 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal PAT1 PF09770.4 CDI74596.1 - 0.019 13.2 21.3 0.021 13.1 14.7 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Herpes_UL87 PF03043.9 CDI74596.1 - 0.056 11.8 1.7 0.067 11.5 1.2 1.0 1 0 0 1 1 1 0 Herpesvirus UL87 family CWC25 PF12542.3 CDI74596.1 - 0.11 12.9 19.6 0.18 12.2 13.6 1.4 1 0 0 1 1 1 0 Pre-mRNA splicing factor Peptidase_U57 PF05582.7 CDI74596.1 - 0.51 9.2 8.3 0.7 8.8 5.7 1.1 1 0 0 1 1 1 0 YabG peptidase U57 FKS1_dom1 PF14288.1 CDI74596.1 - 0.74 9.7 5.0 1.2 9.0 3.5 1.3 1 0 0 1 1 1 0 1,3-beta-glucan synthase subunit FKS1, domain-1 Borrelia_P83 PF05262.6 CDI74596.1 - 0.74 8.0 12.3 0.85 7.8 8.5 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein Pex14_N PF04695.8 CDI74596.1 - 0.9 9.5 14.8 1.7 8.7 10.3 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region FLO_LFY PF01698.11 CDI74596.1 - 1.2 7.8 12.4 1.5 7.5 8.6 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein DDHD PF02862.12 CDI74596.1 - 1.5 8.5 7.9 1.9 8.2 5.4 1.3 1 0 0 1 1 1 0 DDHD domain BTV_NS2 PF04514.7 CDI74596.1 - 1.7 7.4 11.1 2.1 7.1 7.7 1.2 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Dicty_REP PF05086.7 CDI74596.1 - 1.8 6.2 7.0 2.1 5.9 4.9 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF2265 PF10023.4 CDI74596.1 - 4.6 6.2 15.9 7.4 5.5 11.0 1.3 1 0 0 1 1 1 0 Predicted aminopeptidase (DUF2265) Sec62 PF03839.11 CDI74596.1 - 6.1 6.1 7.3 8.1 5.7 5.1 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 Ycf1 PF05758.7 CDI74596.1 - 8 4.0 14.1 8.8 3.9 9.8 1.1 1 0 0 1 1 1 0 Ycf1 Gag_spuma PF03276.9 CDI74596.1 - 8.5 4.5 22.3 12 4.0 15.5 1.1 1 0 0 1 1 1 0 Spumavirus gag protein Hid1 PF12722.2 CDI74596.1 - 8.8 3.8 13.4 10 3.6 9.3 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein BAF1_ABF1 PF04684.8 CDI74597.1 - 0.0049 15.7 26.1 0.0064 15.4 18.1 1.1 1 0 0 1 1 1 1 BAF1 / ABF1 chromatin reorganising factor DDRGK PF09756.4 CDI74597.1 - 0.029 13.7 7.0 0.026 13.9 4.9 1.1 1 0 0 1 1 1 0 DDRGK domain Pex14_N PF04695.8 CDI74597.1 - 0.039 13.9 15.0 0.046 13.7 10.4 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF2722 PF10846.3 CDI74597.1 - 0.054 12.5 20.2 0.056 12.4 14.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) TMEM171 PF15471.1 CDI74597.1 - 0.11 11.2 3.0 0.14 10.8 2.0 1.2 1 0 0 1 1 1 0 Transmembrane protein family 171 FimP PF09766.4 CDI74597.1 - 0.14 11.1 14.8 0.14 11.1 10.3 1.1 1 0 0 1 1 1 0 Fms-interacting protein Suf PF05843.9 CDI74597.1 - 0.29 10.8 12.1 0.27 10.9 8.4 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) FAM176 PF14851.1 CDI74597.1 - 0.29 10.7 4.3 0.31 10.7 3.0 1.1 1 0 0 1 1 1 0 FAM176 family Med15 PF09606.5 CDI74597.1 - 0.45 8.6 33.4 0.49 8.5 23.2 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal PEHE PF15275.1 CDI74597.1 - 0.64 10.4 7.2 0.72 10.3 5.0 1.1 1 0 0 1 1 1 0 PEHE domain Gti1_Pac2 PF09729.4 CDI74597.1 - 1.2 9.0 4.2 1.3 8.8 2.9 1.1 1 0 0 1 1 1 0 Gti1/Pac2 family CDK5_activator PF03261.10 CDI74597.1 - 1.5 8.0 14.7 1.6 7.9 10.2 1.0 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein DDHD PF02862.12 CDI74597.1 - 1.6 8.4 6.2 1.7 8.3 4.3 1.1 1 0 0 1 1 1 0 DDHD domain eIF-3_zeta PF05091.7 CDI74597.1 - 2.2 6.8 10.3 2.1 6.8 7.1 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) OATP PF03137.15 CDI74597.1 - 2.2 6.2 4.9 1.9 6.4 3.4 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family RNA_pol_Rbc25 PF08292.7 CDI74597.1 - 2.4 8.3 6.3 3.8 7.7 4.4 1.3 1 0 0 1 1 1 0 RNA polymerase III subunit Rpc25 DUF2126 PF09899.4 CDI74597.1 - 3 5.7 7.6 3.2 5.6 5.3 1.0 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) DUF2819 PF10995.3 CDI74597.1 - 3.2 6.4 12.8 3.2 6.4 8.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2819) Band_3_cyto PF07565.8 CDI74597.1 - 3.3 7.1 8.5 3.2 7.1 5.9 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Spt20 PF12090.3 CDI74597.1 - 4 6.7 12.7 4.6 6.5 8.8 1.2 1 0 0 1 1 1 0 Spt20 family Glyco_transf_15 PF01793.11 CDI74597.1 - 4.2 6.2 7.0 3.8 6.3 4.9 1.1 1 0 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase Hid1 PF12722.2 CDI74597.1 - 4.3 4.8 10.0 4.5 4.8 7.0 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein FAM60A PF15396.1 CDI74597.1 - 4.4 6.9 7.9 4.4 6.9 5.5 1.1 1 0 0 1 1 1 0 Protein Family FAM60A UPF0560 PF10577.4 CDI74597.1 - 4.4 5.4 13.1 4.1 5.5 9.1 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Serinc PF03348.10 CDI74597.1 - 4.7 5.8 7.0 4.1 6.0 4.9 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) Pex16 PF08610.5 CDI74597.1 - 5.1 5.9 7.9 4.8 6.0 5.5 1.0 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) MCPVI PF02993.9 CDI74597.1 - 5.3 7.1 12.9 6.5 6.8 9.0 1.0 1 0 0 1 1 1 0 Minor capsid protein VI Peptidase_S49_N PF08496.5 CDI74597.1 - 5.6 6.7 8.5 8.8 6.1 5.9 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal XRN_N PF03159.13 CDI74597.1 - 6.4 6.0 9.6 6.6 6.0 6.6 1.1 1 0 0 1 1 1 0 XRN 5'-3' exonuclease N-terminus CDK2AP PF09806.4 CDI74597.1 - 8.4 6.5 21.6 10 6.2 15.0 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein HGTP_anticodon2 PF12745.2 CDI74597.1 - 10 5.2 9.8 9.6 5.2 6.8 1.1 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs Utp14 PF04615.8 CDI74598.1 - 0.011 13.9 41.0 0.015 13.5 28.4 1.1 1 0 0 1 1 1 0 Utp14 protein DUF572 PF04502.8 CDI74598.1 - 0.043 13.0 40.7 0.061 12.5 28.2 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) Glyco_hydro_1 PF00232.13 CDI74598.1 - 4.9 5.2 13.6 0.33 9.0 4.4 2.1 2 0 0 2 2 2 0 Glycosyl hydrolase family 1 Helicase_C PF00271.26 CDI74599.1 - 2.7e-21 75.1 0.0 2.7e-21 75.1 0.0 3.3 3 1 0 3 3 3 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 CDI74599.1 - 7.8e-08 31.7 0.1 1.8e-07 30.6 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) DEAD PF00270.24 CDI74599.1 - 4.2e-05 23.0 34.1 9.7e-05 21.9 20.3 2.8 2 1 0 2 2 2 1 DEAD/DEAH box helicase SseC PF04888.7 CDI74599.1 - 0.00098 18.5 18.9 0.00098 18.5 13.1 6.0 6 0 0 6 6 6 1 Secretion system effector C (SseC) like family Med15 PF09606.5 CDI74599.1 - 0.0019 16.5 35.0 0.0019 16.5 24.3 4.1 3 2 0 3 3 3 1 ARC105 or Med15 subunit of Mediator complex non-fungal Dehydrin PF00257.14 CDI74599.1 - 0.0032 17.7 8.9 0.0032 17.7 6.2 6.5 3 3 1 4 4 4 1 Dehydrin Ribosomal_60s PF00428.14 CDI74599.1 - 0.011 16.0 12.2 0.011 16.0 8.4 5.3 4 1 1 5 5 5 0 60s Acidic ribosomal protein Plasmodium_Vir PF05795.6 CDI74599.1 - 2.1 7.4 21.1 0.82 8.8 0.4 3.7 3 0 0 3 3 3 0 Plasmodium vivax Vir protein Daxx PF03344.10 CDI74600.1 - 0.23 9.9 40.4 0.26 9.7 28.0 1.0 1 0 0 1 1 1 0 Daxx Family Spore_coat_CotO PF14153.1 CDI74600.1 - 1.1 8.6 38.1 1.4 8.3 26.4 1.2 1 0 0 1 1 1 0 Spore coat protein CotO BUD22 PF09073.5 CDI74600.1 - 1.2 8.0 47.7 1.4 7.9 33.0 1.1 1 0 0 1 1 1 0 BUD22 NPR3 PF03666.8 CDI74600.1 - 1.8 6.9 24.1 2.3 6.6 16.7 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Herpes_glycop PF01528.11 CDI74600.1 - 2.1 6.9 5.3 2.6 6.6 3.7 1.1 1 0 0 1 1 1 0 Herpesvirus glycoprotein M CENP-T PF15511.1 CDI74600.1 - 2.7 7.1 20.2 3.5 6.7 14.0 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Nop14 PF04147.7 CDI74600.1 - 3.7 5.3 41.0 4.8 4.9 28.5 1.1 1 0 0 1 1 1 0 Nop14-like family XPC-binding PF09280.6 CDI74602.1 - 1.8e-13 49.7 11.1 1.8e-13 49.7 7.7 3.7 2 1 1 3 3 3 1 XPC-binding domain PAT1 PF09770.4 CDI74602.1 - 0.021 13.1 73.8 0.025 12.8 51.1 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Draxin PF15550.1 CDI74602.1 - 2.6 7.6 33.8 0.32 10.6 8.9 2.3 2 0 0 2 2 2 0 Draxin SR-25 PF10500.4 CDI74603.1 - 0.00012 21.6 19.4 0.00012 21.6 13.4 2.7 3 0 0 3 3 3 2 Nuclear RNA-splicing-associated protein Spore_YhcN_YlaJ PF09580.5 CDI74603.1 - 0.0075 16.4 4.7 0.0075 16.4 3.2 2.2 2 0 0 2 2 2 1 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) Apt1 PF10351.4 CDI74603.1 - 3.2 6.5 31.3 2.8 6.6 7.7 2.1 2 0 0 2 2 2 0 Golgi-body localisation protein domain Corona_nucleoca PF00937.13 CDI74603.1 - 4.9 6.0 38.8 0.29 10.0 8.1 2.2 2 0 0 2 2 2 0 Coronavirus nucleocapsid protein DUF2052 PF09747.4 CDI74603.1 - 9.9 6.0 33.6 0.68 9.8 9.5 2.1 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) Pro_isomerase PF00160.16 CDI74604.1 - 5.5e-18 65.6 0.0 6.1e-18 65.4 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD AsnA PF03590.10 CDI74605.1 - 4.5e-80 268.6 0.0 5.5e-80 268.3 0.0 1.0 1 0 0 1 1 1 1 Aspartate-ammonia ligase VPS11_C PF12451.3 CDI74606.1 - 2.6e-08 33.5 0.0 5.1e-08 32.6 0.0 1.5 1 0 0 1 1 1 1 Vacuolar protein sorting protein 11 C terminal Clathrin PF00637.15 CDI74606.1 - 9.2e-06 25.3 0.4 3.7e-05 23.3 0.1 2.2 2 1 0 2 2 2 1 Region in Clathrin and VPS Vps39_2 PF10367.4 CDI74606.1 - 0.0011 19.1 0.3 0.0031 17.6 0.2 1.8 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 PHD PF00628.24 CDI74606.1 - 0.0097 15.5 2.2 0.034 13.8 1.5 2.0 1 0 0 1 1 1 1 PHD-finger DUF1409 PF07197.7 CDI74606.1 - 0.014 15.4 1.1 0.047 13.7 0.8 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1409) zf-C3HC4 PF00097.20 CDI74606.1 - 0.069 12.8 5.3 0.24 11.0 3.7 2.0 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CDI74606.1 - 0.092 12.4 7.5 0.27 10.9 5.2 1.8 1 0 0 1 1 1 0 zinc-RING finger domain zf-rbx1 PF12678.2 CDI74606.1 - 1.9 8.6 9.9 0.77 9.9 0.9 3.4 2 1 1 3 3 3 0 RING-H2 zinc finger zf-RING_2 PF13639.1 CDI74606.1 - 2.9 7.8 11.6 0.6 9.9 5.1 2.2 2 1 0 2 2 2 0 Ring finger domain IMCp PF12314.3 CDI74607.1 - 4.6e-07 29.8 52.1 8.4e-06 25.8 13.0 4.0 2 1 2 4 4 4 3 Inner membrane complex protein ubiquitin PF00240.18 CDI74608.1 - 9.2e-10 37.7 0.3 1e-06 27.9 0.0 2.3 2 0 0 2 2 2 2 Ubiquitin family Rad60-SLD PF11976.3 CDI74608.1 - 0.00017 21.1 0.4 0.0014 18.3 0.2 2.1 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like YukD PF08817.5 CDI74608.1 - 0.0014 19.1 0.0 0.0032 17.9 0.0 1.6 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukD UN_NPL4 PF11543.3 CDI74608.1 - 0.0087 16.3 0.0 0.03 14.5 0.0 1.9 1 0 0 1 1 1 1 Nuclear pore localisation protein NPL4 ANAPC15 PF15243.1 CDI74609.1 - 0.15 12.1 12.6 0.044 13.8 6.3 1.9 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 15 CDC45 PF02724.9 CDI74609.1 - 0.38 8.7 4.9 0.5 8.3 3.4 1.1 1 0 0 1 1 1 0 CDC45-like protein Trypan_PARP PF05887.6 CDI74609.1 - 0.92 9.3 11.0 1.3 8.8 7.7 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Mog1 PF04603.7 CDI74610.1 - 8.3e-23 80.9 0.0 1e-22 80.6 0.0 1.1 1 0 0 1 1 1 1 Ran-interacting Mog1 protein GvpO PF05800.6 CDI74610.1 - 0.14 12.0 0.1 0.38 10.6 0.0 1.7 2 0 0 2 2 2 0 Gas vesicle synthesis protein GvpO AAA_11 PF13086.1 CDI74611.1 - 3.4 7.1 11.0 5.9 6.3 7.6 1.4 1 1 0 1 1 1 0 AAA domain Notch PF00066.12 CDI74612.1 - 6.2e-49 163.9 115.6 2.9e-10 40.2 9.3 6.8 6 1 1 7 7 7 6 LNR domain Fasciclin PF02469.17 CDI74614.1 - 1e-06 28.8 0.0 2.8e-06 27.3 0.0 1.7 1 1 0 1 1 1 1 Fasciclin domain Myb_DNA-binding PF00249.26 CDI74615.1 - 4e-09 36.3 0.3 1.1e-08 34.9 0.2 1.8 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 CDI74615.1 - 8.6e-07 28.9 0.9 3.3e-06 27.1 0.6 2.0 1 0 0 1 1 1 1 Myb-like DNA-binding domain EF-hand_7 PF13499.1 CDI74618.1 - 2.6e-14 53.1 0.0 2.9e-13 49.7 0.1 2.1 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 CDI74618.1 - 9.6e-13 46.4 0.1 5.5e-06 25.3 0.1 3.3 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.1 CDI74618.1 - 2.5e-10 39.8 0.4 3.2e-06 26.6 0.0 2.7 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.1 CDI74618.1 - 3.8e-10 38.7 0.3 3.1e-05 23.4 0.1 3.5 3 0 0 3 3 3 2 EF-hand domain EF-hand_5 PF13202.1 CDI74618.1 - 7.2e-08 31.4 0.7 6.7e-06 25.2 0.0 2.8 3 0 0 3 3 3 1 EF hand SPARC_Ca_bdg PF10591.4 CDI74618.1 - 0.0028 17.6 0.0 0.0034 17.3 0.0 1.4 1 1 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.1 CDI74618.1 - 0.006 16.4 0.0 0.012 15.5 0.0 1.5 1 0 0 1 1 1 1 EF-hand domain MotA_activ PF09114.5 CDI74618.1 - 0.091 12.5 0.1 0.2 11.4 0.1 1.6 1 1 0 1 1 1 0 Transcription factor MotA, activation domain MHCassoc_trimer PF08831.5 CDI74618.1 - 0.1 12.4 0.5 0.48 10.3 0.2 2.0 2 0 0 2 2 2 0 Class II MHC-associated invariant chain trimerisation domain DUF2937 PF11157.3 CDI74620.1 - 2.4 7.4 11.8 8.7 5.6 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2937) Exonuc_VII_L PF02601.10 CDI74620.1 - 3.3 6.8 10.9 0.54 9.4 3.2 2.0 2 0 0 2 2 2 0 Exonuclease VII, large subunit Surfac_D-trimer PF09006.6 CDI74620.1 - 9.6 6.0 9.8 1 9.1 2.1 2.6 2 0 0 2 2 2 0 Lung surfactant protein D coiled-coil trimerisation CS PF04969.11 CDI74621.1 - 5.7e-17 62.0 0.0 9.7e-17 61.2 0.0 1.4 1 0 0 1 1 1 1 CS domain Nudc_N PF14050.1 CDI74621.1 - 5e-16 58.4 0.7 1.5e-15 56.8 0.5 1.8 1 0 0 1 1 1 1 N-terminal conserved domain of Nudc. RAB3GAP2_N PF14655.1 CDI74621.1 - 0.059 12.3 3.0 0.098 11.6 2.1 1.3 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Fucose_iso_N2 PF07882.7 CDI74621.1 - 0.064 12.9 4.3 0.31 10.6 0.3 2.3 2 0 0 2 2 2 0 L-fucose isomerase, second N-terminal domain Muted PF14942.1 CDI74621.1 - 0.48 10.2 18.2 2.1 8.1 8.0 2.2 2 0 0 2 2 2 0 Organelle biogenesis, Muted-like protein DUF3899 PF13038.1 CDI74621.1 - 1.1 9.4 3.4 2.9 8.0 2.4 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3899) Hid1 PF12722.2 CDI74621.1 - 2 5.9 5.7 3.2 5.2 3.9 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Borrelia_P83 PF05262.6 CDI74622.1 - 0.97 7.6 5.3 1.2 7.3 3.7 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein Cnd1 PF12717.2 CDI74623.1 - 0.037 13.8 0.6 0.51 10.1 0.0 3.2 3 1 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.17 CDI74623.1 - 0.062 13.4 5.5 12 6.2 0.0 5.4 4 0 0 4 4 4 0 HEAT repeat Coatomer_WDAD PF04053.9 CDI74624.1 - 6.7e-05 21.8 0.6 0.00088 18.1 0.1 2.1 2 0 0 2 2 2 1 Coatomer WD associated region TPR_7 PF13176.1 CDI74624.1 - 0.015 15.0 2.6 1.6 8.6 0.0 5.4 5 1 2 7 7 7 0 Tetratricopeptide repeat Sec16_C PF12931.2 CDI74624.1 - 0.03 14.0 0.0 0.062 13.0 0.0 1.4 1 0 0 1 1 1 0 Sec23-binding domain of Sec16 TPR_12 PF13424.1 CDI74624.1 - 0.13 12.2 0.0 0.13 12.2 0.0 3.9 5 0 0 5 5 5 0 Tetratricopeptide repeat CLASP_N PF12348.3 CDI74628.1 - 0.00061 19.2 1.2 2.6 7.3 0.1 4.0 3 2 0 3 3 3 2 CLASP N terminal RIX1 PF08167.7 CDI74628.1 - 0.0013 18.4 5.2 0.004 16.8 0.1 3.6 4 0 0 4 4 4 1 rRNA processing/ribosome biogenesis Proteasom_PSMB PF10508.4 CDI74628.1 - 0.0052 15.1 3.5 0.039 12.2 0.6 2.4 2 0 0 2 2 2 1 Proteasome non-ATPase 26S subunit HEAT PF02985.17 CDI74628.1 - 0.014 15.4 15.9 2.9 8.1 0.1 7.0 6 0 0 6 6 6 0 HEAT repeat HEAT_EZ PF13513.1 CDI74628.1 - 4.4 7.9 37.9 0.34 11.4 0.3 8.3 9 0 0 9 9 9 0 HEAT-like repeat Adaptin_N PF01602.15 CDI74628.1 - 6.8 4.8 8.4 0.71 8.1 0.7 2.5 3 0 0 3 3 3 0 Adaptin N terminal region WD40 PF00400.27 CDI74629.1 - 5.4e-06 26.0 10.3 3.5 7.6 0.0 5.8 6 0 0 6 6 6 4 WD domain, G-beta repeat DUF1510 PF07423.6 CDI74631.1 - 0.00011 21.6 5.2 0.00012 21.5 3.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) DUF4512 PF14975.1 CDI74631.1 - 0.0065 17.2 2.5 0.0076 17.0 1.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4512) TRAP_alpha PF03896.11 CDI74631.1 - 0.0087 15.0 1.9 0.009 15.0 1.3 1.0 1 0 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit RBP_receptor PF14752.1 CDI74631.1 - 0.012 13.9 6.4 0.012 13.9 4.5 1.0 1 0 0 1 1 1 0 Retinol binding protein receptor FAM176 PF14851.1 CDI74631.1 - 0.016 14.9 1.9 0.017 14.8 1.3 1.1 1 0 0 1 1 1 0 FAM176 family DUF106 PF01956.11 CDI74631.1 - 0.016 14.7 11.6 0.017 14.6 8.1 1.0 1 0 0 1 1 1 0 Integral membrane protein DUF106 DUF2149 PF09919.4 CDI74631.1 - 0.03 14.4 9.1 0.035 14.2 6.3 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2149) Bap31 PF05529.7 CDI74631.1 - 0.031 13.7 11.0 0.036 13.5 7.6 1.2 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like Ctr PF04145.10 CDI74631.1 - 0.032 14.2 3.0 0.037 14.0 2.1 1.1 1 0 0 1 1 1 0 Ctr copper transporter family Cytochrom_B_N PF00033.14 CDI74631.1 - 0.04 13.2 0.0 0.047 13.0 0.0 1.1 1 0 0 1 1 1 0 Cytochrome b(N-terminal)/b6/petB RIC3 PF15361.1 CDI74631.1 - 0.051 13.8 9.9 0.057 13.6 6.8 1.1 1 0 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 FHIPEP PF00771.15 CDI74631.1 - 0.074 11.3 5.5 0.074 11.3 3.8 1.1 1 0 0 1 1 1 0 FHIPEP family SID-1_RNA_chan PF13965.1 CDI74631.1 - 0.083 11.0 3.6 0.082 11.0 2.5 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Folate_carrier PF01770.13 CDI74631.1 - 0.094 11.2 6.2 0.093 11.2 4.3 1.0 1 0 0 1 1 1 0 Reduced folate carrier DUF4446 PF14584.1 CDI74631.1 - 0.11 12.3 7.2 0.11 12.2 5.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) Peroxin-13_N PF04088.8 CDI74631.1 - 0.13 12.2 4.8 0.14 12.1 3.3 1.1 1 0 0 1 1 1 0 Peroxin 13, N-terminal region Herpes_glycop PF01528.11 CDI74631.1 - 0.13 10.8 1.6 0.14 10.8 1.1 1.0 1 0 0 1 1 1 0 Herpesvirus glycoprotein M Ycf1 PF05758.7 CDI74631.1 - 0.15 9.7 9.9 0.14 9.8 6.8 1.0 1 0 0 1 1 1 0 Ycf1 Kei1 PF08552.6 CDI74631.1 - 0.22 11.1 4.6 0.24 11.0 3.2 1.2 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 OATP PF03137.15 CDI74631.1 - 0.35 8.8 8.8 0.37 8.7 6.1 1.0 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family GRP PF07172.6 CDI74631.1 - 0.36 11.3 5.4 0.57 10.6 3.8 1.4 1 1 0 1 1 1 0 Glycine rich protein family Serinc PF03348.10 CDI74631.1 - 0.36 9.5 9.1 0.37 9.4 6.3 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) K_trans PF02705.11 CDI74631.1 - 0.4 8.9 1.7 0.45 8.8 1.2 1.0 1 0 0 1 1 1 0 K+ potassium transporter DUF3260 PF11658.3 CDI74631.1 - 0.51 8.4 9.9 0.51 8.4 6.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3260) DUF3357 PF11837.3 CDI74631.1 - 0.55 10.1 6.0 2.4 8.0 4.1 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF3357) Neur_chan_memb PF02932.11 CDI74631.1 - 0.61 9.9 5.8 0.63 9.8 4.1 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Nucleoside_tran PF01733.13 CDI74631.1 - 0.65 9.0 3.8 0.69 9.0 2.6 1.0 1 0 0 1 1 1 0 Nucleoside transporter Pap_E4 PF02711.9 CDI74631.1 - 1.6 9.6 12.9 1.9 9.3 8.9 1.1 1 0 0 1 1 1 0 E4 protein YfhO PF09586.5 CDI74631.1 - 1.7 6.5 8.4 1.6 6.6 5.8 1.0 1 0 0 1 1 1 0 Bacterial membrane protein YfhO Mem_trans PF03547.13 CDI74631.1 - 1.9 6.6 6.2 2.1 6.5 4.3 1.1 1 0 0 1 1 1 0 Membrane transport protein Endonuc_Holl PF10107.4 CDI74631.1 - 2 8.0 15.2 2.1 7.9 10.6 1.0 1 0 0 1 1 1 0 Endonuclease related to archaeal Holliday junction resolvase ABC2_membrane_2 PF12679.2 CDI74631.1 - 2.3 7.0 4.4 2.6 6.8 3.0 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF2946 PF11162.3 CDI74631.1 - 2.3 8.4 8.1 2.6 8.2 5.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2946) PXA PF02194.10 CDI74631.1 - 3.8 7.0 8.7 4.4 6.8 6.0 1.1 1 0 0 1 1 1 0 PXA domain SHR3_chaperone PF08229.6 CDI74631.1 - 3.8 6.4 18.5 4.8 6.0 12.8 1.1 1 0 0 1 1 1 0 ER membrane protein SH3 DUF2126 PF09899.4 CDI74631.1 - 3.9 5.3 9.9 3.9 5.3 6.9 1.0 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) SeqA PF03925.8 CDI74631.1 - 4.4 6.9 15.2 5.1 6.7 10.5 1.0 1 0 0 1 1 1 0 SeqA protein Pex16 PF08610.5 CDI74631.1 - 4.8 6.0 15.8 5.5 5.8 11.0 1.0 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) ALG3 PF05208.8 CDI74631.1 - 5.7 6.0 6.4 5.9 6.0 4.4 1.0 1 0 0 1 1 1 0 ALG3 protein DUF1980 PF09323.5 CDI74631.1 - 6.1 6.5 9.4 6.9 6.3 6.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) YABBY PF04690.8 CDI74631.1 - 6.3 7.0 10.0 6.5 6.9 6.9 1.0 1 0 0 1 1 1 0 YABBY protein COX16 PF14138.1 CDI74631.1 - 6.6 6.9 12.8 15 5.8 8.9 1.6 1 1 0 1 1 1 0 Cytochrome c oxidase assembly protein COX16 DUF2215 PF10225.4 CDI74631.1 - 7.9 5.8 8.0 8.4 5.7 5.5 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) UPF0565 PF10561.4 CDI74631.1 - 8 5.2 12.9 8.8 5.1 8.9 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0565 Peptidase_S49_N PF08496.5 CDI74631.1 - 8.5 6.1 13.6 9.9 5.9 9.4 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Baculo_PP31 PF05311.6 CDI74631.1 - 9.1 5.4 14.2 10 5.3 9.8 1.0 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) Spore_coat_CotO PF14153.1 CDI74632.1 - 1.6e-06 27.7 17.1 1.6e-06 27.7 11.8 2.1 2 0 0 2 2 2 1 Spore coat protein CotO SPX PF03105.14 CDI74632.1 - 8.5e-05 22.4 21.0 0.00042 20.1 6.6 2.1 2 0 0 2 2 2 2 SPX domain DEAD PF00270.24 CDI74632.1 - 0.00016 21.1 67.0 0.0098 15.3 46.4 2.6 1 1 0 1 1 1 1 DEAD/DEAH box helicase Ycf1 PF05758.7 CDI74632.1 - 0.00018 19.3 11.2 0.00018 19.3 7.8 2.0 2 0 0 2 2 2 1 Ycf1 SAGA-Tad1 PF12767.2 CDI74632.1 - 0.0015 18.2 30.6 0.0046 16.6 12.7 2.2 2 0 0 2 2 2 2 Transcriptional regulator of RNA polII, SAGA, subunit FLO_LFY PF01698.11 CDI74632.1 - 0.0021 16.9 11.7 0.0021 16.9 8.1 2.2 2 0 0 2 2 2 1 Floricaula / Leafy protein SAPS PF04499.10 CDI74632.1 - 0.0035 16.0 11.3 0.0035 16.0 7.8 2.1 2 0 0 2 2 2 1 SIT4 phosphatase-associated protein Tom37_C PF11801.3 CDI74632.1 - 0.0039 17.0 1.7 0.0039 17.0 1.2 2.7 3 0 0 3 3 2 1 Tom37 C-terminal domain PAT1 PF09770.4 CDI74632.1 - 0.0056 14.9 68.6 0.037 12.2 36.7 2.1 2 0 0 2 2 2 2 Topoisomerase II-associated protein PAT1 DUF966 PF06136.8 CDI74632.1 - 0.014 14.8 24.1 0.026 13.9 8.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF966) Pex14_N PF04695.8 CDI74632.1 - 0.015 15.3 2.8 0.015 15.3 1.9 3.3 2 1 0 2 2 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Zip PF02535.17 CDI74632.1 - 0.23 10.4 18.3 0.0088 15.0 3.0 2.2 2 0 0 2 2 2 0 ZIP Zinc transporter DUF4045 PF13254.1 CDI74632.1 - 0.28 10.4 30.1 0.8 8.9 1.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4045) Pox_Ag35 PF03286.9 CDI74632.1 - 0.28 10.6 26.7 1.1 8.7 2.0 2.1 2 0 0 2 2 2 0 Pox virus Ag35 surface protein DDHD PF02862.12 CDI74632.1 - 0.34 10.6 33.6 1.2 8.8 13.4 2.2 2 0 0 2 2 2 0 DDHD domain CDC45 PF02724.9 CDI74632.1 - 0.46 8.4 40.3 0.071 11.1 4.7 2.1 2 0 0 2 2 2 0 CDC45-like protein CENP-T PF15511.1 CDI74632.1 - 0.49 9.5 38.0 1.8 7.7 12.0 2.9 3 0 0 3 3 3 0 Centromere kinetochore component CENP-T Herpes_UL87 PF03043.9 CDI74632.1 - 0.56 8.5 13.8 1.1 7.6 9.6 1.4 1 1 0 1 1 1 0 Herpesvirus UL87 family FAM60A PF15396.1 CDI74632.1 - 0.93 9.1 32.5 0.6 9.8 13.1 2.2 2 0 0 2 2 2 0 Protein Family FAM60A HlyD_2 PF12700.2 CDI74632.1 - 1.1 8.3 26.3 0.026 13.6 8.9 2.1 2 0 0 2 2 2 0 HlyD family secretion protein Otopetrin PF03189.8 CDI74632.1 - 1.4 7.8 11.1 0.37 9.7 3.7 2.1 2 0 0 2 2 2 0 Otopetrin DUF2413 PF10310.4 CDI74632.1 - 1.6 7.4 41.6 0.81 8.4 18.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2413) DUF1510 PF07423.6 CDI74632.1 - 1.6 8.0 45.2 0.17 11.2 16.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) Nha1_C PF08619.5 CDI74632.1 - 1.6 7.8 38.3 0.37 10.0 13.9 2.1 2 0 0 2 2 2 0 Alkali metal cation/H+ antiporter Nha1 C terminus Lin-8 PF03353.10 CDI74632.1 - 1.7 7.8 35.1 0.95 8.6 15.3 2.2 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist Dsh_C PF12316.3 CDI74632.1 - 1.8 8.6 19.6 1.4 8.9 0.9 2.2 2 0 0 2 2 2 0 Segment polarity protein dishevelled (Dsh) C terminal Neur_chan_memb PF02932.11 CDI74632.1 - 2.5 7.9 24.9 3.8 7.3 11.8 2.1 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Raftlin PF15250.1 CDI74632.1 - 3.4 6.0 33.3 0.43 9.0 12.9 2.1 2 0 0 2 2 2 0 Raftlin LMBR1 PF04791.11 CDI74632.1 - 3.7 6.0 13.0 0.67 8.4 4.9 2.0 2 0 0 2 2 2 0 LMBR1-like membrane protein CRT10 PF08728.5 CDI74632.1 - 3.7 5.4 14.7 0.35 8.8 3.7 2.0 2 0 0 2 2 2 0 CRT10 CDK5_activator PF03261.10 CDI74632.1 - 3.9 6.7 24.8 0.24 10.6 9.5 2.2 2 0 0 2 2 2 0 Cyclin-dependent kinase 5 activator protein Hid1 PF12722.2 CDI74632.1 - 4.8 4.7 37.2 1.1 6.8 15.6 2.0 2 0 0 2 2 2 0 High-temperature-induced dauer-formation protein Parvo_coat PF00740.13 CDI74632.1 - 6.7 5.5 33.8 1 8.2 14.9 2.0 2 0 0 2 2 2 0 Parvovirus coat protein VP2 RabGAP-TBC PF00566.13 CDI74635.1 - 4.4e-30 104.7 3.6 4.1e-28 98.3 2.5 3.0 1 1 0 1 1 1 1 Rab-GTPase-TBC domain Toxin_11 PF07473.6 CDI74635.1 - 0.24 11.2 2.2 18 5.3 0.1 2.5 2 0 0 2 2 2 0 Spasmodic peptide gm9a Oleosin PF01277.12 CDI74635.1 - 0.67 9.5 9.6 4.4 6.9 0.3 2.5 2 0 0 2 2 2 0 Oleosin gag-asp_proteas PF13975.1 CDI74637.1 - 0.0054 16.5 0.0 0.012 15.3 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 CDI74637.1 - 0.043 14.3 0.0 0.087 13.3 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease DUF4207 PF13904.1 CDI74639.1 - 0.021 14.1 0.9 0.021 14.1 0.6 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4207) PAT1 PF09770.4 CDI74639.1 - 0.73 8.0 104.9 0.011 14.0 16.4 2.1 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 Neur_chan_memb PF02932.11 CDI74640.1 - 0.27 11.0 8.6 0.34 10.7 6.0 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF605 PF04652.11 CDI74640.1 - 0.7 9.2 21.3 0.72 9.1 14.8 1.1 1 0 0 1 1 1 0 Vta1 like Herpes_gE PF02480.11 CDI74640.1 - 1.4 7.1 13.5 5.2 5.2 9.3 1.8 1 1 0 1 1 1 0 Alphaherpesvirus glycoprotein E SR-25 PF10500.4 CDI74641.1 - 0.00032 20.2 10.1 0.00032 20.2 7.0 2.1 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein Med15 PF09606.5 CDI74641.1 - 0.0018 16.5 13.3 0.0021 16.3 9.2 1.1 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal Plasmodium_Vir PF05795.6 CDI74641.1 - 0.0087 15.3 4.9 0.011 15.0 3.4 1.0 1 0 0 1 1 1 1 Plasmodium vivax Vir protein Kelch_3 PF13415.1 CDI74641.1 - 0.013 15.6 0.5 0.92 9.7 0.2 2.6 2 1 0 2 2 1 0 Galactose oxidase, central domain ICL PF00463.16 CDI74641.1 - 0.015 13.5 0.8 0.02 13.1 0.6 1.1 1 0 0 1 1 1 0 Isocitrate lyase family Kelch_1 PF01344.20 CDI74641.1 - 0.018 14.5 5.7 0.13 11.8 4.0 2.2 1 1 0 1 1 1 0 Kelch motif RAB3GAP2_C PF14656.1 CDI74641.1 - 0.028 12.5 2.4 0.043 11.9 1.7 1.2 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit C-terminus Kelch_4 PF13418.1 CDI74641.1 - 0.036 13.8 0.2 2.7 7.8 0.0 2.5 2 0 0 2 2 2 0 Galactose oxidase, central domain DUF572 PF04502.8 CDI74641.1 - 0.13 11.4 15.2 0.18 11.0 10.5 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF572) Pex14_N PF04695.8 CDI74641.1 - 0.15 12.1 24.4 0.3 11.1 0.0 2.1 1 1 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Kelch_2 PF07646.10 CDI74641.1 - 0.41 10.4 7.2 18 5.3 5.0 2.7 1 1 0 1 1 1 0 Kelch motif FimP PF09766.4 CDI74641.1 - 0.53 9.2 10.7 0.69 8.9 7.4 1.1 1 0 0 1 1 1 0 Fms-interacting protein Phostensin_N PF13916.1 CDI74641.1 - 0.57 10.1 6.4 0.94 9.4 4.5 1.3 1 0 0 1 1 1 0 PP1-regulatory protein, Phostensin N-terminal CDK5_activator PF03261.10 CDI74641.1 - 0.66 9.2 14.8 0.82 8.9 10.3 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein Kelch_6 PF13964.1 CDI74641.1 - 1.7 8.9 6.9 9.4 6.5 2.8 2.8 2 1 0 2 2 1 0 Kelch motif SprA-related PF12118.3 CDI74641.1 - 2.4 7.3 24.9 1.9 7.7 13.0 2.1 2 0 0 2 2 2 0 SprA-related family CagX PF03524.10 CDI74641.1 - 3.4 6.8 8.1 4.7 6.4 5.6 1.1 1 0 0 1 1 1 0 Conjugal transfer protein Tom37_C PF11801.3 CDI74641.1 - 3.9 7.3 10.6 5.4 6.8 7.3 1.3 1 1 0 1 1 1 0 Tom37 C-terminal domain DUF4175 PF13779.1 CDI74641.1 - 4.7 4.7 16.0 5.7 4.5 11.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Sec62 PF03839.11 CDI74641.1 - 5.6 6.3 6.7 9.3 5.5 4.6 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 DUF4199 PF13858.1 CDI74641.1 - 7.9 6.3 6.6 1.5 8.6 2.2 1.5 2 0 0 2 2 1 0 Protein of unknown function (DUF4199) DUF2371 PF10177.4 CDI74641.1 - 8 6.3 6.1 7.8 6.3 2.6 2.2 1 1 1 2 2 2 0 Uncharacterised conserved protein (DUF2371) Surface_antigen PF11054.3 CDI74642.1 - 1.4e-32 113.1 18.8 2.3e-09 36.9 0.6 7.2 2 2 3 6 6 6 5 Sporozoite TA4 surface antigen Surface_antigen PF11054.3 CDI74644.1 - 2.2e-30 105.9 19.6 2.6e-10 40.1 2.8 5.6 1 1 2 4 4 4 4 Sporozoite TA4 surface antigen MT PF12777.2 CDI74644.1 - 0.03 13.0 0.1 0.054 12.2 0.0 1.3 1 0 0 1 1 1 0 Microtubule-binding stalk of dynein motor Med15 PF09606.5 CDI74645.1 - 1.1 7.4 121.8 0.99 7.5 29.4 2.3 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal Ribosomal_60s PF00428.14 CDI74645.1 - 1.1 9.6 20.0 8.3 6.8 0.3 2.8 2 0 0 2 2 2 0 60s Acidic ribosomal protein XAP5 PF04921.9 CDI74646.1 - 4.6 6.7 37.9 0.16 11.5 5.9 3.0 2 1 1 3 3 3 0 XAP5, circadian clock regulator N6_N4_Mtase PF01555.13 CDI74647.1 - 0.00058 19.4 0.0 75 2.6 0.1 4.4 4 1 0 4 4 4 0 DNA methylase DUF2029 PF09594.5 CDI74647.1 - 0.005 16.3 21.6 0.44 10.0 0.1 4.3 4 0 0 4 4 4 3 Protein of unknown function (DUF2029) Ribosomal_60s PF00428.14 CDI74647.1 - 2.5 8.5 77.3 0.088 13.2 4.7 6.1 6 0 0 6 6 6 0 60s Acidic ribosomal protein PepSY_2 PF13670.1 CDI74648.1 - 0.0046 16.8 2.0 0.0046 16.8 1.4 5.2 5 2 0 5 5 5 1 Peptidase propeptide and YPEB domain WSS_VP PF12175.3 CDI74648.1 - 0.83 8.6 5.4 6 5.9 0.2 2.2 1 1 1 2 2 2 0 White spot syndrome virus structural envelope protein VP Plasmodium_Vir PF05795.6 CDI74649.1 - 0.44 9.6 9.5 0.14 11.3 0.8 2.1 2 0 0 2 2 2 0 Plasmodium vivax Vir protein Na_trans_assoc PF06512.8 CDI74649.1 - 3.5 7.5 15.6 1.6 8.6 0.9 2.3 2 0 0 2 2 2 0 Sodium ion transport-associated Med15 PF09606.5 CDI74650.1 - 0.59 8.2 54.8 0.73 7.9 38.0 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal MIP-T3 PF10243.4 CDI74651.1 - 0.0079 14.7 36.2 0.01 14.3 25.1 1.1 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 PRP38_assoc PF12871.2 CDI74651.1 - 0.011 16.2 66.1 0.034 14.6 15.8 2.2 2 0 0 2 2 2 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term Trypan_PARP PF05887.6 CDI74651.1 - 0.16 11.7 12.6 2.7 7.8 0.2 2.1 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) Pacs-1 PF10254.4 CDI74651.1 - 1.7 7.1 8.4 0.67 8.5 4.4 1.3 1 1 0 1 1 1 0 PACS-1 cytosolic sorting protein Trypan_PARP PF05887.6 CDI74652.1 - 0.0039 17.0 56.7 0.0041 16.9 20.9 2.8 2 1 1 3 3 3 2 Procyclic acidic repetitive protein (PARP) DUF966 PF06136.8 CDI74652.1 - 0.55 9.5 13.4 0.91 8.8 9.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF966) MDFI PF15316.1 CDI74652.1 - 7 6.6 7.2 14 5.6 5.0 1.6 1 0 0 1 1 1 0 MyoD family inhibitor DUF4647 PF15504.1 CDI74652.1 - 7.5 5.2 22.4 11 4.7 15.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4647) DUF2562 PF10814.3 CDI74653.1 - 0.0044 16.9 0.6 0.0073 16.2 0.4 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2562) Med15 PF09606.5 CDI74653.1 - 0.0091 14.2 19.2 0.0094 14.2 13.3 1.1 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal RskA PF10099.4 CDI74653.1 - 0.02 14.6 0.2 0.024 14.3 0.2 1.3 1 0 0 1 1 1 0 Anti-sigma-K factor rskA Pex14_N PF04695.8 CDI74653.1 - 0.044 13.8 11.3 0.072 13.1 4.3 2.1 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region SbcCD_C PF13558.1 CDI74653.1 - 0.054 13.4 0.7 0.054 13.4 0.5 1.5 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit BRF1 PF07741.8 CDI74653.1 - 0.1 12.7 3.4 0.17 12.1 2.4 1.3 1 0 0 1 1 1 0 Brf1-like TBP-binding domain PAT1 PF09770.4 CDI74653.1 - 0.11 10.6 10.1 0.096 10.9 7.0 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Neur_chan_memb PF02932.11 CDI74653.1 - 0.14 12.0 4.5 0.16 11.8 3.1 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region GSG-1 PF07803.6 CDI74653.1 - 0.18 11.3 4.0 0.29 10.7 2.7 1.3 1 0 0 1 1 1 0 GSG1-like protein G-alpha PF00503.15 CDI74653.1 - 0.24 10.0 3.2 0.29 9.7 2.2 1.0 1 0 0 1 1 1 0 G-protein alpha subunit DUF1675 PF07897.6 CDI74653.1 - 0.29 10.9 10.0 0.34 10.7 6.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) DUF4175 PF13779.1 CDI74653.1 - 1.7 6.2 16.1 1.8 6.1 11.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) FimP PF09766.4 CDI74653.1 - 1.9 7.5 11.3 2.3 7.1 7.9 1.1 1 0 0 1 1 1 0 Fms-interacting protein LNP1 PF15419.1 CDI74653.1 - 1.9 8.5 11.7 2.3 8.3 8.1 1.1 1 0 0 1 1 1 0 Leukemia NUP98 fusion partner 1 DUF4407 PF14362.1 CDI74653.1 - 4.2 6.2 8.7 5.4 5.8 6.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Androgen_recep PF02166.11 CDI74653.1 - 7.3 5.3 17.0 8.9 5.0 11.8 1.0 1 0 0 1 1 1 0 Androgen receptor Phosphoprotein PF00922.12 CDI74653.1 - 8.9 5.4 9.8 11 5.0 6.8 1.1 1 0 0 1 1 1 0 Vesiculovirus phosphoprotein Peptidase_U57 PF05582.7 CDI74655.1 - 4.7 6.0 18.8 5 5.9 13.0 1.1 1 0 0 1 1 1 0 YabG peptidase U57 DDRGK PF09756.4 CDI74656.1 - 2.9 7.2 28.4 2 7.8 9.1 2.1 2 0 0 2 2 2 0 DDRGK domain SURF2 PF05477.6 CDI74656.1 - 8.2 5.4 22.7 0.094 11.8 6.1 2.0 2 0 0 2 2 2 0 Surfeit locus protein 2 (SURF2) CDC27 PF09507.5 CDI74658.1 - 0.0002 20.7 13.3 0.0002 20.7 9.2 4.9 4 2 1 5 5 5 1 DNA polymerase subunit Cdc27 Suf PF05843.9 CDI74658.1 - 0.0091 15.7 4.0 0.0091 15.7 2.8 6.2 4 2 2 6 6 6 1 Suppressor of forked protein (Suf) RskA PF10099.4 CDI74659.1 - 1.8 8.2 25.8 0.053 13.2 2.5 2.3 1 1 1 2 2 2 0 Anti-sigma-K factor rskA PAT1 PF09770.4 CDI74660.1 - 0.0036 15.6 55.3 0.0041 15.4 38.3 1.2 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 DUF2163 PF09931.4 CDI74660.1 - 0.047 13.4 0.6 0.094 12.4 0.4 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2163) DUF4613 PF15390.1 CDI74660.1 - 0.39 8.8 6.4 0.46 8.5 4.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) DUF2232 PF09991.4 CDI74662.1 - 0.00018 20.6 5.1 0.00022 20.3 3.5 1.1 1 0 0 1 1 1 1 Predicted membrane protein (DUF2232) Pex14_N PF04695.8 CDI74662.1 - 0.00022 21.2 23.8 0.00022 21.2 16.5 1.5 1 1 1 2 2 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region FimP PF09766.4 CDI74662.1 - 0.00024 20.2 14.6 0.00031 19.9 10.1 1.2 1 0 0 1 1 1 1 Fms-interacting protein Serinc PF03348.10 CDI74662.1 - 0.00036 19.3 7.7 0.00042 19.1 5.4 1.1 1 0 0 1 1 1 1 Serine incorporator (Serinc) OATP PF03137.15 CDI74662.1 - 0.00083 17.5 6.2 0.001 17.2 4.3 1.1 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family Suf PF05843.9 CDI74662.1 - 0.0016 18.2 15.3 0.0019 18.0 10.6 1.1 1 0 0 1 1 1 1 Suppressor of forked protein (Suf) DUF4557 PF15101.1 CDI74662.1 - 0.0017 18.2 21.3 0.0021 17.9 14.8 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4557) OPT PF03169.10 CDI74662.1 - 0.0019 16.7 0.2 0.0029 16.1 0.1 1.3 1 1 0 1 1 1 1 OPT oligopeptide transporter protein DUF3260 PF11658.3 CDI74662.1 - 0.0028 15.9 11.4 0.003 15.7 7.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3260) DUF106 PF01956.11 CDI74662.1 - 0.0036 16.8 7.7 0.0045 16.5 5.3 1.1 1 0 0 1 1 1 1 Integral membrane protein DUF106 CMV_1a PF12467.3 CDI74662.1 - 0.0038 17.6 13.9 0.0049 17.2 9.6 1.0 1 0 0 1 1 1 1 Cucumber mosaic virus 1a protein family Ctr PF04145.10 CDI74662.1 - 0.0039 17.2 6.5 0.0052 16.8 4.5 1.2 1 0 0 1 1 1 1 Ctr copper transporter family RR_TM4-6 PF06459.7 CDI74662.1 - 0.0053 16.6 10.5 0.0059 16.5 7.2 1.1 1 0 0 1 1 1 1 Ryanodine Receptor TM 4-6 AIF_C PF14721.1 CDI74662.1 - 0.0078 16.4 8.3 0.0095 16.1 5.8 1.2 1 0 0 1 1 1 1 Apoptosis-inducing factor, mitochondrion-associated, C-term DUF2370 PF10176.4 CDI74662.1 - 0.0081 15.5 2.5 0.0093 15.3 1.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2370) MDFI PF15316.1 CDI74662.1 - 0.01 15.8 9.2 0.012 15.5 6.4 1.1 1 0 0 1 1 1 0 MyoD family inhibitor Peptidase_S49_N PF08496.5 CDI74662.1 - 0.011 15.5 7.9 0.013 15.3 5.5 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal PalH PF08733.5 CDI74662.1 - 0.011 14.6 3.5 0.014 14.2 2.4 1.3 1 0 0 1 1 1 0 PalH/RIM21 DUF913 PF06025.7 CDI74662.1 - 0.013 14.2 6.8 0.014 14.1 4.7 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) PBP1_TM PF14812.1 CDI74662.1 - 0.015 15.5 0.6 0.021 15.1 0.4 1.1 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Raftlin PF15250.1 CDI74662.1 - 0.017 13.6 8.4 0.019 13.5 5.8 1.0 1 0 0 1 1 1 0 Raftlin Peptidase_M56 PF05569.6 CDI74662.1 - 0.018 14.0 4.5 0.021 13.8 3.1 1.2 1 0 0 1 1 1 0 BlaR1 peptidase M56 RP-C_C PF11800.3 CDI74662.1 - 0.023 14.3 9.7 0.03 14.0 6.7 1.2 1 0 0 1 1 1 0 Replication protein C C-terminal region Kei1 PF08552.6 CDI74662.1 - 0.023 14.3 11.6 0.037 13.6 8.0 1.4 1 1 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 Bac_luciferase PF00296.15 CDI74662.1 - 0.023 13.7 5.2 0.028 13.5 3.6 1.1 1 0 0 1 1 1 0 Luciferase-like monooxygenase Folate_carrier PF01770.13 CDI74662.1 - 0.026 13.0 5.4 0.031 12.7 3.7 1.2 1 0 0 1 1 1 0 Reduced folate carrier SAGA-Tad1 PF12767.2 CDI74662.1 - 0.027 14.1 10.9 0.029 14.0 7.5 1.1 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit HCO3_cotransp PF00955.16 CDI74662.1 - 0.028 13.1 5.9 0.032 12.9 4.1 1.1 1 0 0 1 1 1 0 HCO3- transporter family MMR1 PF08505.5 CDI74662.1 - 0.029 14.4 18.1 0.036 14.0 12.6 1.0 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein Med15 PF09606.5 CDI74662.1 - 0.029 12.5 45.9 0.038 12.2 31.8 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DHHW PF14286.1 CDI74662.1 - 0.03 13.6 9.1 0.031 13.6 6.3 1.0 1 0 0 1 1 1 0 DHHW protein GAGA_bind PF06217.7 CDI74662.1 - 0.03 14.2 8.7 0.034 14.1 6.0 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family Anoctamin PF04547.7 CDI74662.1 - 0.037 12.6 4.1 0.038 12.6 2.8 1.1 1 0 0 1 1 1 0 Calcium-activated chloride channel Herpes_DNAp_acc PF04929.7 CDI74662.1 - 0.037 12.9 10.0 0.045 12.7 6.9 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Peptidase_U57 PF05582.7 CDI74662.1 - 0.039 12.9 7.9 0.044 12.7 5.5 1.0 1 0 0 1 1 1 0 YabG peptidase U57 NPR3 PF03666.8 CDI74662.1 - 0.043 12.3 7.9 0.049 12.1 5.5 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF912 PF06024.7 CDI74662.1 - 0.049 13.6 12.8 0.27 11.3 8.9 2.0 1 1 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) UPF0118 PF01594.11 CDI74662.1 - 0.052 12.5 0.2 0.062 12.2 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function DUF20 Peptidase_S15 PF02129.13 CDI74662.1 - 0.052 12.9 10.4 0.065 12.6 7.2 1.0 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) SID-1_RNA_chan PF13965.1 CDI74662.1 - 0.057 11.5 4.3 0.065 11.4 3.0 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 FAM60A PF15396.1 CDI74662.1 - 0.057 13.1 6.6 0.068 12.9 4.6 1.2 1 0 0 1 1 1 0 Protein Family FAM60A TraT PF05818.7 CDI74662.1 - 0.06 12.7 10.8 0.089 12.1 7.5 1.2 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein DUF2215 PF10225.4 CDI74662.1 - 0.061 12.7 6.4 0.078 12.4 4.5 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) DUF1510 PF07423.6 CDI74662.1 - 0.062 12.6 13.6 0.076 12.3 9.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DUF4079 PF13301.1 CDI74662.1 - 0.074 13.0 2.8 0.099 12.6 2.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4079) FemAB PF02388.11 CDI74662.1 - 0.076 11.6 10.5 0.09 11.4 7.3 1.1 1 0 0 1 1 1 0 FemAB family DUF4192 PF13830.1 CDI74662.1 - 0.079 12.5 11.3 0.094 12.3 7.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4192) Ycf1 PF05758.7 CDI74662.1 - 0.091 10.4 8.8 0.093 10.4 6.1 1.0 1 0 0 1 1 1 0 Ycf1 PSD1 PF07587.6 CDI74662.1 - 0.099 12.0 9.6 0.13 11.6 6.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1553) Band_3_cyto PF07565.8 CDI74662.1 - 0.11 11.9 11.2 0.13 11.7 7.7 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Pox_P35 PF03213.9 CDI74662.1 - 0.12 11.3 3.1 0.14 11.1 2.1 1.1 1 0 0 1 1 1 0 Poxvirus P35 protein Hamartin PF04388.7 CDI74662.1 - 0.14 10.8 10.1 0.16 10.6 7.0 1.0 1 0 0 1 1 1 0 Hamartin protein Dala_Dala_lig_N PF01820.16 CDI74662.1 - 0.14 12.4 4.8 0.19 12.0 3.3 1.2 1 0 0 1 1 1 0 D-ala D-ala ligase N-terminus SpoIIIAH PF12685.2 CDI74662.1 - 0.15 11.5 15.8 0.2 11.1 10.9 1.1 1 0 0 1 1 1 0 SpoIIIAH-like protein Neur_chan_memb PF02932.11 CDI74662.1 - 0.16 11.7 6.5 0.2 11.4 4.5 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF3899 PF13038.1 CDI74662.1 - 0.17 12.0 0.8 0.41 10.8 0.6 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF3899) DUF3112 PF11309.3 CDI74662.1 - 0.19 11.5 2.3 1.3 8.8 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3112) eIF-3_zeta PF05091.7 CDI74662.1 - 0.2 10.2 17.2 0.22 10.0 11.9 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DDHD PF02862.12 CDI74662.1 - 0.2 11.3 11.3 0.24 11.1 7.9 1.1 1 0 0 1 1 1 0 DDHD domain NARP1 PF12569.3 CDI74662.1 - 0.21 10.3 15.2 0.26 9.9 10.5 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Paramyxo_ncap PF00973.14 CDI74662.1 - 0.23 10.1 8.9 0.26 9.9 6.2 1.0 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein SeqA PF03925.8 CDI74662.1 - 0.24 11.1 9.8 0.29 10.8 6.8 1.2 1 0 0 1 1 1 0 SeqA protein MRI PF15325.1 CDI74662.1 - 0.24 12.3 6.2 0.33 11.9 4.3 1.2 1 0 0 1 1 1 0 Modulator of retrovirus infection PAT1 PF09770.4 CDI74662.1 - 0.25 9.5 37.4 0.27 9.4 25.9 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TFIIA PF03153.8 CDI74662.1 - 0.25 11.2 32.2 0.3 10.9 22.3 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Rtf2 PF04641.7 CDI74662.1 - 0.25 10.5 13.4 0.3 10.2 9.3 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger DUF822 PF05687.8 CDI74662.1 - 0.26 11.6 9.2 0.32 11.3 6.4 1.2 1 0 0 1 1 1 0 Plant protein of unknown function (DUF822) Tim54 PF11711.3 CDI74662.1 - 0.26 9.8 9.0 0.3 9.6 6.3 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 AUX_IAA PF02309.11 CDI74662.1 - 0.27 10.9 9.2 0.29 10.8 6.4 1.1 1 0 0 1 1 1 0 AUX/IAA family Dynamin_N PF00350.18 CDI74662.1 - 0.27 11.0 6.0 0.32 10.8 4.1 1.1 1 0 0 1 1 1 0 Dynamin family RIC3 PF15361.1 CDI74662.1 - 0.28 11.4 14.4 0.34 11.1 10.0 1.2 1 0 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 Gti1_Pac2 PF09729.4 CDI74662.1 - 0.32 10.8 6.5 0.36 10.6 4.5 1.1 1 0 0 1 1 1 0 Gti1/Pac2 family PP2C_2 PF13672.1 CDI74662.1 - 0.33 10.3 9.9 0.51 9.7 6.9 1.3 1 0 0 1 1 1 0 Protein phosphatase 2C GOLD_2 PF13897.1 CDI74662.1 - 0.35 11.0 2.3 0.41 10.8 1.6 1.3 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking BORG_CEP PF14957.1 CDI74662.1 - 0.36 11.7 8.1 0.45 11.4 5.6 1.1 1 0 0 1 1 1 0 Cdc42 effector DUF4064 PF13273.1 CDI74662.1 - 0.36 10.9 3.4 4.1 7.5 2.4 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF4064) Sec62 PF03839.11 CDI74662.1 - 0.36 10.1 7.4 0.44 9.9 5.1 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 DUF4045 PF13254.1 CDI74662.1 - 0.36 10.0 11.2 0.4 9.8 7.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) FLO_LFY PF01698.11 CDI74662.1 - 0.38 9.5 12.6 0.43 9.3 8.8 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein AAT PF03417.11 CDI74662.1 - 0.38 10.1 8.0 0.46 9.9 5.6 1.1 1 0 0 1 1 1 0 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase Glyco_transf_15 PF01793.11 CDI74662.1 - 0.39 9.6 13.2 0.49 9.2 9.2 1.0 1 0 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase DUF605 PF04652.11 CDI74662.1 - 0.39 10.0 22.9 0.47 9.7 15.9 1.1 1 0 0 1 1 1 0 Vta1 like SpoIIP PF07454.6 CDI74662.1 - 0.4 9.8 9.8 0.5 9.4 6.8 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) PIH1 PF08190.7 CDI74662.1 - 0.44 9.9 17.4 0.51 9.7 12.1 1.1 1 0 0 1 1 1 0 pre-RNA processing PIH1/Nop17 COX6A PF02046.10 CDI74662.1 - 0.48 10.3 6.2 0.29 11.0 2.6 1.7 1 1 1 2 2 2 0 Cytochrome c oxidase subunit VIa DUF2126 PF09899.4 CDI74662.1 - 0.48 8.3 9.4 0.51 8.3 6.5 1.0 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) AMP-binding PF00501.23 CDI74662.1 - 0.5 8.6 4.1 0.62 8.3 2.8 1.1 1 0 0 1 1 1 0 AMP-binding enzyme CTP_transf_3 PF02348.14 CDI74662.1 - 0.54 9.8 7.7 0.64 9.5 5.3 1.0 1 0 0 1 1 1 0 Cytidylyltransferase DUF3357 PF11837.3 CDI74662.1 - 0.54 10.1 6.5 6.3 6.7 3.7 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3357) SpoVR PF04293.8 CDI74662.1 - 0.54 8.5 11.4 0.6 8.4 7.9 1.0 1 0 0 1 1 1 0 SpoVR like protein CDK5_activator PF03261.10 CDI74662.1 - 0.57 9.4 12.0 0.64 9.2 8.3 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein DUF4446 PF14584.1 CDI74662.1 - 0.61 9.9 7.5 0.58 9.9 4.7 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF4446) BNR_3 PF13859.1 CDI74662.1 - 0.64 9.0 9.1 0.78 8.7 6.3 1.1 1 0 0 1 1 1 0 BNR repeat-like domain FNIP_N PF14636.1 CDI74662.1 - 0.65 10.4 15.3 0.82 10.1 10.6 1.1 1 0 0 1 1 1 0 Folliculin-interacting protein N-terminus RNA_pol_Rpb1_5 PF04998.12 CDI74662.1 - 0.67 9.1 7.0 0.78 8.9 4.8 1.0 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 TCP PF03634.8 CDI74662.1 - 0.76 10.1 15.8 0.98 9.7 10.9 1.2 1 0 0 1 1 1 0 TCP family transcription factor Dicty_REP PF05086.7 CDI74662.1 - 0.78 7.4 15.7 0.91 7.2 10.9 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Trp_oprn_chp PF09534.5 CDI74662.1 - 0.79 9.3 17.1 2.3 7.7 8.2 2.0 1 1 1 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) UPF0560 PF10577.4 CDI74662.1 - 0.8 7.8 19.9 0.92 7.6 13.8 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Glt_symporter PF03616.9 CDI74662.1 - 0.81 8.1 11.3 1.7 7.0 7.8 1.5 1 1 0 1 1 1 0 Sodium/glutamate symporter Baculo_PP31 PF05311.6 CDI74662.1 - 0.84 8.8 15.4 0.97 8.6 10.7 1.1 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) DUF2048 PF09752.4 CDI74662.1 - 0.87 8.4 10.5 1 8.1 7.3 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2048) TMEM223 PF14640.1 CDI74662.1 - 0.87 9.4 7.2 3.6 7.4 5.0 1.9 1 1 0 1 1 1 0 Transmembrane protein 223 DUF2899 PF11449.3 CDI74662.1 - 0.87 8.7 9.1 6.7 5.7 6.3 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2899) Nucleo_P87 PF07267.6 CDI74662.1 - 0.91 8.1 12.9 1 7.9 9.0 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 DUF607 PF04678.8 CDI74662.1 - 0.94 9.3 13.0 1.2 9.0 9.0 1.0 1 0 0 1 1 1 0 Protein of unknown function, DUF607 PPP4R2 PF09184.6 CDI74662.1 - 1 8.8 10.7 1.2 8.6 7.4 1.0 1 0 0 1 1 1 0 PPP4R2 Spc7_N PF15402.1 CDI74662.1 - 1.1 7.2 16.5 1.2 7.0 11.5 1.0 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 F-protein PF00469.15 CDI74662.1 - 1.1 8.5 10.3 1.3 8.3 7.2 1.1 1 0 0 1 1 1 0 Negative factor, (F-Protein) or Nef DUF1675 PF07897.6 CDI74662.1 - 1.2 8.9 9.3 1.5 8.5 6.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) CD20 PF04103.10 CDI74662.1 - 1.2 9.0 12.6 10 6.0 8.8 2.0 1 1 0 1 1 1 0 CD20-like family Nucleoside_tran PF01733.13 CDI74662.1 - 1.3 8.1 10.0 3.3 6.7 7.0 1.6 1 1 1 2 2 2 0 Nucleoside transporter CobT PF06213.7 CDI74662.1 - 1.3 8.0 13.0 1.6 7.8 9.0 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT IncA PF04156.9 CDI74662.1 - 1.5 8.3 30.0 2.1 7.9 20.5 1.4 1 1 0 1 1 1 0 IncA protein Cellulose_synt PF03552.9 CDI74662.1 - 1.5 6.9 4.3 1.6 6.8 3.0 1.1 1 0 0 1 1 1 0 Cellulose synthase DUF4448 PF14610.1 CDI74662.1 - 1.7 8.0 8.0 4.1 6.8 5.1 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF4448) PP_M1 PF03012.9 CDI74662.1 - 1.8 7.8 12.2 2.1 7.6 8.4 1.1 1 0 0 1 1 1 0 Phosphoprotein DUF940 PF06082.6 CDI74662.1 - 1.8 7.0 10.6 2.1 6.8 7.3 1.1 1 0 0 1 1 1 0 Bacterial putative lipoprotein (DUF940) HemX PF04375.9 CDI74662.1 - 2 6.8 30.0 2.4 6.6 20.8 1.0 1 0 0 1 1 1 0 HemX DUF844 PF05815.6 CDI74662.1 - 2.1 7.0 11.8 2.8 6.7 8.2 1.3 1 0 0 1 1 1 0 Baculovirus protein of unknown function (DUF844) DUF1980 PF09323.5 CDI74662.1 - 2.1 8.0 10.7 2.7 7.7 7.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) PGA_cap PF09587.5 CDI74662.1 - 2.2 7.5 7.8 2.9 7.1 5.4 1.2 1 0 0 1 1 1 0 Bacterial capsule synthesis protein PGA_cap DUF3408 PF11888.3 CDI74662.1 - 2.4 8.0 13.5 4.1 7.3 9.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) NapE PF06796.6 CDI74662.1 - 2.8 7.3 5.9 28 4.1 4.1 2.4 1 1 0 1 1 1 0 Periplasmic nitrate reductase protein NapE DUF3450 PF11932.3 CDI74662.1 - 2.8 7.1 31.5 3.7 6.7 21.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) 7tm_1 PF00001.16 CDI74662.1 - 3.1 6.8 9.0 17 4.4 6.2 1.9 1 1 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) Gag_spuma PF03276.9 CDI74662.1 - 3.4 5.9 31.5 4 5.6 21.8 1.1 1 0 0 1 1 1 0 Spumavirus gag protein DUF3381 PF11861.3 CDI74662.1 - 3.4 7.1 13.9 4.3 6.8 9.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) Helicase_RecD PF05127.9 CDI74662.1 - 3.5 7.2 12.7 4.5 6.8 8.8 1.1 1 0 0 1 1 1 0 Helicase UPF0233 PF06781.7 CDI74662.1 - 3.6 7.2 8.1 50 3.6 5.6 2.2 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0233) Gastrin PF00918.12 CDI74662.1 - 3.8 8.3 27.5 0.6 10.9 16.4 1.7 1 1 1 2 2 1 0 Gastrin/cholecystokinin family LMBR1 PF04791.11 CDI74662.1 - 4 5.8 6.3 4.7 5.6 4.4 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Pneumo_phosprot PF02478.11 CDI74662.1 - 4.4 6.7 7.3 5.2 6.5 5.0 1.1 1 0 0 1 1 1 0 Pneumovirus phosphoprotein DUF2407_C PF13373.1 CDI74662.1 - 4.5 7.1 8.6 2.3 8.1 3.8 2.0 1 1 1 2 2 1 0 DUF2407 C-terminal domain CPSF100_C PF13299.1 CDI74662.1 - 6.3 6.9 14.6 8.2 6.5 10.1 1.1 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal GNT-I PF03071.10 CDI74662.1 - 6.4 5.1 11.2 7.2 5.0 7.8 1.0 1 0 0 1 1 1 0 GNT-I family Spore_coat_CotO PF14153.1 CDI74662.1 - 6.5 6.1 23.3 8.4 5.7 16.1 1.1 1 0 0 1 1 1 0 Spore coat protein CotO HD-ZIP_N PF04618.7 CDI74662.1 - 6.7 7.2 7.6 9.6 6.7 5.3 1.3 1 0 0 1 1 1 0 HD-ZIP protein N terminus HA2 PF04408.18 CDI74662.1 - 7.1 6.7 7.1 20 5.2 4.9 1.8 1 1 0 1 1 1 0 Helicase associated domain (HA2) Pal1 PF08316.6 CDI74662.1 - 7.1 7.0 9.9 9.2 6.7 6.9 1.2 1 0 0 1 1 1 0 Pal1 cell morphology protein G-alpha PF00503.15 CDI74662.1 - 7.3 5.1 15.5 9.2 4.8 10.8 1.0 1 0 0 1 1 1 0 G-protein alpha subunit DUF1764 PF08576.5 CDI74662.1 - 7.7 7.3 18.1 11 6.8 12.6 1.2 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) DUF2371 PF10177.4 CDI74662.1 - 8.4 6.2 8.9 40 4.0 6.2 1.9 1 1 0 1 1 1 0 Uncharacterised conserved protein (DUF2371) DUF3708 PF12501.3 CDI74662.1 - 8.4 6.1 14.1 13 5.6 9.8 1.2 1 0 0 1 1 1 0 Phosphate ATP-binding cassette transporter SpaB_C PF14028.1 CDI74662.1 - 8.9 5.7 8.7 11 5.4 6.0 1.1 1 0 0 1 1 1 0 SpaB C-terminal domain DUF1345 PF07077.6 CDI74662.1 - 9.1 5.7 10.1 1.7 8.1 0.4 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF1345) Neur_chan_memb PF02932.11 CDI74663.1 - 3.4 7.4 9.7 25 4.6 4.2 3.0 2 1 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region SPX PF03105.14 CDI74666.1 - 0.011 15.5 10.5 0.024 14.4 5.0 2.3 2 1 0 2 2 2 0 SPX domain Med15 PF09606.5 CDI74666.1 - 0.015 13.4 59.7 0.0097 14.1 27.1 2.3 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal MIF4G_like PF09088.6 CDI74666.1 - 0.021 14.2 0.0 5.7 6.3 0.0 2.4 2 0 0 2 2 2 0 MIF4G like PAT1 PF09770.4 CDI74666.1 - 4.5 5.3 49.2 1.7 6.8 24.8 2.2 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 E_Pc_C PF06752.7 CDI74667.1 - 1.5 8.3 11.6 0.8 9.1 4.1 2.5 2 0 0 2 2 2 0 Enhancer of Polycomb C-terminus zf-CCCH PF00642.19 CDI74669.1 - 5.9e-10 38.5 13.2 2.5e-05 23.8 1.1 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_5 PF13893.1 CDI74669.1 - 4.3e-09 36.0 0.0 7e-09 35.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CDI74669.1 - 4.2e-05 23.0 0.0 7.8e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CDI74669.1 - 0.03 14.2 0.0 0.061 13.3 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Rhodanese PF00581.15 CDI74670.1 - 0.00095 19.5 0.0 0.1 12.9 0.0 2.2 2 0 0 2 2 2 2 Rhodanese-like domain Pkinase PF00069.20 CDI74671.1 - 8.4e-13 48.0 0.0 1.4e-06 27.7 0.0 3.2 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.12 CDI74671.1 - 4.7e-07 29.1 0.0 1.6e-05 24.1 0.0 2.3 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 CDI74671.1 - 0.00088 18.3 0.0 0.0015 17.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like SR-25 PF10500.4 CDI74673.1 - 2.2e-05 24.0 6.0 2.7e-05 23.7 4.1 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein T4SS-DNA_transf PF02534.9 CDI74673.1 - 0.011 14.2 5.6 0.013 14.1 3.9 1.1 1 0 0 1 1 1 0 Type IV secretory system Conjugative DNA transfer HCV_NS5a_C PF12941.2 CDI74673.1 - 0.041 13.4 9.5 0.034 13.7 5.8 1.4 1 1 0 1 1 1 0 HCV NS5a protein C-terminal region Pox_F17 PF04767.7 CDI74673.1 - 0.078 13.2 0.1 0.078 13.2 0.1 2.1 1 1 1 2 2 2 0 DNA-binding 11 kDa phosphoprotein DUF4569 PF15133.1 CDI74673.1 - 0.16 11.3 14.7 0.19 11.0 10.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4569) PAT1 PF09770.4 CDI74673.1 - 0.18 10.0 31.2 0.2 9.8 21.6 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Transposase_mut PF00872.13 CDI74673.1 - 0.22 10.0 6.3 0.27 9.7 4.3 1.0 1 0 0 1 1 1 0 Transposase, Mutator family DUF2201_N PF13203.1 CDI74673.1 - 0.25 10.4 15.3 0.29 10.2 10.6 1.0 1 0 0 1 1 1 0 Putative metallopeptidase domain DUF3474 PF11960.3 CDI74673.1 - 0.42 10.6 4.2 0.52 10.3 2.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3474) SprA-related PF12118.3 CDI74673.1 - 0.56 9.4 31.8 0.72 9.1 22.0 1.1 1 0 0 1 1 1 0 SprA-related family FHIPEP PF00771.15 CDI74673.1 - 0.64 8.2 8.2 0.8 7.9 5.7 1.1 1 0 0 1 1 1 0 FHIPEP family DUF4045 PF13254.1 CDI74673.1 - 0.66 9.1 14.9 0.8 8.9 10.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) TFIIA PF03153.8 CDI74673.1 - 0.78 9.5 28.6 0.98 9.2 19.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit GAGA_bind PF06217.7 CDI74673.1 - 0.86 9.5 11.4 0.92 9.4 7.9 1.0 1 0 0 1 1 1 0 GAGA binding protein-like family Macoilin PF09726.4 CDI74673.1 - 0.98 7.6 10.2 1.4 7.0 7.1 1.2 1 0 0 1 1 1 0 Transmembrane protein Cwf_Cwc_15 PF04889.7 CDI74673.1 - 1.1 8.9 15.7 1.4 8.6 10.9 1.0 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Band_3_cyto PF07565.8 CDI74673.1 - 1.1 8.7 10.0 1.6 8.1 6.9 1.3 1 0 0 1 1 1 0 Band 3 cytoplasmic domain TraG-D_C PF12696.2 CDI74673.1 - 1.2 8.9 14.4 0.054 13.3 5.6 1.7 1 1 1 2 2 2 0 TraM recognition site of TraD and TraG AUX_IAA PF02309.11 CDI74673.1 - 1.5 8.5 9.9 2 8.0 6.9 1.2 1 0 0 1 1 1 0 AUX/IAA family DUF1675 PF07897.6 CDI74673.1 - 2.5 7.9 12.5 2.9 7.6 8.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) HlyD_2 PF12700.2 CDI74673.1 - 3.5 6.6 14.1 4.4 6.3 9.8 1.1 1 0 0 1 1 1 0 HlyD family secretion protein DUF4175 PF13779.1 CDI74673.1 - 3.6 5.1 29.6 4.6 4.8 20.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Herpes_DNAp_acc PF04929.7 CDI74673.1 - 3.9 6.3 17.5 4.6 6.0 12.1 1.0 1 0 0 1 1 1 0 Herpes DNA replication accessory factor HAUS6_N PF14661.1 CDI74673.1 - 4 6.7 15.2 4.9 6.4 10.5 1.0 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Presenilin PF01080.12 CDI74673.1 - 4.5 6.0 13.5 5.4 5.7 9.4 1.1 1 0 0 1 1 1 0 Presenilin MRP-S31 PF15433.1 CDI74673.1 - 5.4 6.3 16.8 6.8 6.0 11.7 1.1 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 CIAPIN1 PF05093.8 CDI74673.1 - 6.4 6.9 8.2 9 6.4 2.6 2.1 2 0 0 2 2 2 0 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis FAM60A PF15396.1 CDI74673.1 - 7.8 6.1 13.5 9.9 5.8 9.4 1.1 1 0 0 1 1 1 0 Protein Family FAM60A DUF912 PF06024.7 CDI74675.1 - 1.7 8.7 7.5 1.8 8.6 0.2 2.8 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF3464 PF11947.3 CDI74675.1 - 2.2 7.7 0.0 2.2 7.7 0.0 3.1 3 1 0 3 3 3 0 Protein of unknown function (DUF3464) BAF1_ABF1 PF04684.8 CDI74676.1 - 0.0008 18.3 15.4 0.0008 18.3 10.7 4.8 3 1 1 4 4 4 2 BAF1 / ABF1 chromatin reorganising factor Gti1_Pac2 PF09729.4 CDI74676.1 - 0.0043 16.9 6.0 0.0043 16.9 4.2 5.3 2 1 0 2 2 2 1 Gti1/Pac2 family Activator_LAG-3 PF11498.3 CDI74676.1 - 0.0073 15.1 17.1 0.0073 15.1 11.8 3.1 3 0 0 3 3 3 2 Transcriptional activator LAG-3 FHIPEP PF00771.15 CDI74676.1 - 0.29 9.4 9.0 0.11 10.7 0.3 2.4 2 0 0 2 2 2 0 FHIPEP family G0-G1_switch_2 PF15103.1 CDI74676.1 - 2.1 8.5 14.5 4.5 7.5 2.8 2.7 2 0 0 2 2 2 0 G0/G1 switch protein 2 DUF788 PF05620.6 CDI74676.1 - 4.1 7.2 19.8 0.08 12.8 1.4 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF788) DUF2149 PF09919.4 CDI74676.1 - 4.9 7.3 9.1 6.2 6.9 1.0 2.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2149) Bud13 PF09736.4 CDI74676.1 - 5.4 7.2 25.6 2.4 8.3 6.4 2.7 2 0 0 2 2 2 0 Pre-mRNA-splicing factor of RES complex eIF_4EBP PF05456.6 CDI74679.1 - 0.026 14.1 11.0 0.039 13.6 7.6 1.4 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) DUF3450 PF11932.3 CDI74679.1 - 0.039 13.2 19.5 0.04 13.1 13.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) FimP PF09766.4 CDI74679.1 - 0.067 12.2 21.5 0.07 12.1 14.9 1.0 1 0 0 1 1 1 0 Fms-interacting protein NARP1 PF12569.3 CDI74679.1 - 0.1 11.3 14.9 0.11 11.2 10.3 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 YqfQ PF14181.1 CDI74679.1 - 0.18 11.8 15.9 0.2 11.6 11.0 1.1 1 0 0 1 1 1 0 YqfQ-like protein OATP PF03137.15 CDI74679.1 - 0.21 9.6 7.0 0.22 9.5 4.9 1.0 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family BORG_CEP PF14957.1 CDI74679.1 - 0.5 11.2 8.3 0.59 11.0 5.8 1.1 1 0 0 1 1 1 0 Cdc42 effector FHIPEP PF00771.15 CDI74679.1 - 0.56 8.4 4.4 0.52 8.5 3.0 1.1 1 0 0 1 1 1 0 FHIPEP family AIF_C PF14721.1 CDI74679.1 - 0.79 9.9 9.2 0.82 9.9 6.4 1.1 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Serinc PF03348.10 CDI74679.1 - 0.86 8.2 10.0 0.91 8.1 7.0 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) RR_TM4-6 PF06459.7 CDI74679.1 - 0.87 9.4 12.9 0.85 9.4 8.9 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 FLO_LFY PF01698.11 CDI74679.1 - 0.9 8.3 10.8 0.94 8.2 7.5 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein FAM176 PF14851.1 CDI74679.1 - 1 9.0 6.6 1.1 8.8 4.6 1.1 1 0 0 1 1 1 0 FAM176 family Peroxin-13_N PF04088.8 CDI74679.1 - 1.4 8.8 9.9 1.7 8.5 6.9 1.1 1 0 0 1 1 1 0 Peroxin 13, N-terminal region Baculo_PP31 PF05311.6 CDI74679.1 - 1.5 8.0 13.4 1.5 8.0 9.3 1.0 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) SprA-related PF12118.3 CDI74679.1 - 1.5 8.0 30.0 1.7 7.9 20.8 1.1 1 0 0 1 1 1 0 SprA-related family RNA_pol_Rpc4 PF05132.9 CDI74679.1 - 1.6 8.7 14.0 1.9 8.4 9.7 1.1 1 0 0 1 1 1 0 RNA polymerase III RPC4 DDHD PF02862.12 CDI74679.1 - 1.7 8.4 12.5 1.7 8.4 8.6 1.0 1 0 0 1 1 1 0 DDHD domain FAM60A PF15396.1 CDI74679.1 - 1.8 8.2 9.5 1.9 8.2 6.6 1.1 1 0 0 1 1 1 0 Protein Family FAM60A Ycf1 PF05758.7 CDI74679.1 - 1.9 6.0 14.0 1.9 6.1 9.7 1.0 1 0 0 1 1 1 0 Ycf1 Tim54 PF11711.3 CDI74679.1 - 2 6.9 12.0 2.1 6.8 8.4 1.0 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Peptidase_U57 PF05582.7 CDI74679.1 - 2.3 7.1 10.3 2.4 7.0 7.1 1.0 1 0 0 1 1 1 0 YabG peptidase U57 DUF3959 PF13105.1 CDI74679.1 - 2.4 7.4 7.5 2.7 7.2 5.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3959) Presenilin PF01080.12 CDI74679.1 - 2.4 6.8 6.9 2.5 6.8 4.8 1.0 1 0 0 1 1 1 0 Presenilin DUF4337 PF14235.1 CDI74679.1 - 2.9 7.7 14.9 3 7.6 10.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) DUF1764 PF08576.5 CDI74679.1 - 3.1 8.6 17.1 3.8 8.3 11.9 1.1 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) AUX_IAA PF02309.11 CDI74679.1 - 3.4 7.3 11.7 3.6 7.2 8.1 1.0 1 0 0 1 1 1 0 AUX/IAA family Dala_Dala_lig_N PF01820.16 CDI74679.1 - 3.5 7.9 6.9 4.3 7.6 4.8 1.2 1 0 0 1 1 1 0 D-ala D-ala ligase N-terminus DUF3987 PF13148.1 CDI74679.1 - 3.6 6.0 11.3 3.8 5.9 7.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) Folate_carrier PF01770.13 CDI74679.1 - 4.4 5.7 8.5 4.8 5.5 5.9 1.0 1 0 0 1 1 1 0 Reduced folate carrier CPSF100_C PF13299.1 CDI74679.1 - 4.9 7.3 11.9 4.9 7.3 8.2 1.1 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Peptidase_S15 PF02129.13 CDI74679.1 - 4.9 6.4 11.1 4.6 6.5 7.7 1.1 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Herpes_DNAp_acc PF04929.7 CDI74679.1 - 5.8 5.7 11.4 6.3 5.6 7.9 1.0 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Pex14_N PF04695.8 CDI74679.1 - 5.9 6.9 21.3 7 6.6 14.8 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region PAT1 PF09770.4 CDI74679.1 - 6.3 4.9 36.3 6.5 4.8 25.1 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Band_3_cyto PF07565.8 CDI74679.1 - 6.4 6.2 13.5 7 6.0 9.4 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain IncA PF04156.9 CDI74679.1 - 6.5 6.2 21.4 7.1 6.1 14.9 1.1 1 0 0 1 1 1 0 IncA protein Dynamin_N PF00350.18 CDI74679.1 - 6.7 6.5 9.0 7.2 6.3 6.2 1.1 1 0 0 1 1 1 0 Dynamin family DUF3464 PF11947.3 CDI74679.1 - 7 6.0 14.2 8.4 5.8 9.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) Gag_spuma PF03276.9 CDI74679.1 - 8.8 4.5 25.6 9.4 4.4 17.8 1.0 1 0 0 1 1 1 0 Spumavirus gag protein DUF912 PF06024.7 CDI74679.1 - 8.9 6.4 8.7 13 5.8 6.0 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Spore_coat_CotO PF14153.1 CDI74679.1 - 9.5 5.6 22.7 11 5.3 15.7 1.1 1 0 0 1 1 1 0 Spore coat protein CotO HlyD_2 PF12700.2 CDI74680.1 - 0.18 10.9 15.3 0.19 10.8 10.6 1.0 1 0 0 1 1 1 0 HlyD family secretion protein NPR3 PF03666.8 CDI74680.1 - 0.18 10.3 16.0 0.22 10.0 11.1 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 CDC45 PF02724.9 CDI74680.1 - 1.9 6.3 15.6 2.3 6.1 10.8 1.1 1 0 0 1 1 1 0 CDC45-like protein Exonuc_VII_L PF02601.10 CDI74680.1 - 2 7.5 13.9 2.4 7.2 9.6 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit GAGA_bind PF06217.7 CDI74680.1 - 2.2 8.1 20.0 2.8 7.8 13.8 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family Cyto_heme_lyase PF01265.12 CDI74680.1 - 7.1 6.1 22.0 9.5 5.7 15.3 1.1 1 0 0 1 1 1 0 Cytochrome c/c1 heme lyase GPCR_chapero_1 PF11904.3 CDI74680.1 - 7.7 5.5 19.9 9.8 5.2 13.8 1.1 1 0 0 1 1 1 0 GPCR-chaperone DUF3535 PF12054.3 CDI74681.1 - 0.042 12.4 8.0 0.049 12.2 5.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3535) Sporozoite_P67 PF05642.6 CDI74681.1 - 0.046 11.5 2.2 0.05 11.4 1.5 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF3439 PF11921.3 CDI74681.1 - 0.059 13.1 0.5 0.073 12.8 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) DREPP PF05558.7 CDI74681.1 - 0.32 10.8 7.3 0.32 10.8 5.1 1.1 1 0 0 1 1 1 0 DREPP plasma membrane polypeptide BAF1_ABF1 PF04684.8 CDI74681.1 - 0.73 8.6 32.5 0.81 8.4 22.5 1.0 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Hist_deacetyl PF00850.14 CDI74681.1 - 1.6 7.9 6.0 1.7 7.8 4.2 1.1 1 0 0 1 1 1 0 Histone deacetylase domain SAGA-Tad1 PF12767.2 CDI74681.1 - 3 7.4 12.5 3.4 7.2 8.7 1.1 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit FAM176 PF14851.1 CDI74681.1 - 3.5 7.2 7.5 4.2 7.0 5.2 1.2 1 0 0 1 1 1 0 FAM176 family DDRGK PF09756.4 CDI74681.1 - 4.2 6.7 14.1 4.6 6.5 9.8 1.1 1 0 0 1 1 1 0 DDRGK domain PIG-S PF10510.4 CDI74681.1 - 5.9 5.4 13.5 7 5.2 9.4 1.1 1 0 0 1 1 1 0 Phosphatidylinositol-glycan biosynthesis class S protein CDK5_activator PF03261.10 CDI74681.1 - 8.9 5.5 15.7 9.1 5.5 10.9 1.0 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein Utp14 PF04615.8 CDI74682.1 - 0.017 13.3 63.3 0.02 13.1 43.9 1.0 1 0 0 1 1 1 0 Utp14 protein Med15 PF09606.5 CDI74682.1 - 0.02 13.0 159.1 0.025 12.8 110.3 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Shadoo PF14999.1 CDI74682.1 - 0.051 13.4 18.6 0.071 12.9 4.3 2.4 2 0 0 2 2 2 0 Shadow of prion protein, neuroprotective PAT1 PF09770.4 CDI74682.1 - 0.36 8.9 123.8 0.44 8.7 85.8 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Asp-B-Hydro_N PF05279.6 CDI74682.1 - 1.3 8.8 45.1 1.6 8.5 31.2 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region DUF1467 PF07330.7 CDI74682.1 - 1.5 8.6 3.9 1.7 8.4 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1467) Daxx PF03344.10 CDI74682.1 - 1.9 6.8 52.4 2.2 6.6 36.3 1.1 1 0 0 1 1 1 0 Daxx Family Caldesmon PF02029.10 CDI74682.1 - 3.9 5.7 48.7 5.2 5.3 33.7 1.2 1 0 0 1 1 1 0 Caldesmon DUF1777 PF08648.7 CDI74682.1 - 4.2 7.0 39.9 6 6.5 27.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) FlxA PF14282.1 CDI74683.1 - 0.0051 16.7 20.0 0.0051 16.7 13.9 7.5 6 1 0 6 6 6 1 FlxA-like protein SPX PF03105.14 CDI74683.1 - 0.02 14.7 41.0 1.8e+02 1.7 28.4 3.8 1 1 0 1 1 1 0 SPX domain SpoIIE PF07228.7 CDI74683.1 - 0.021 14.5 0.1 0.021 14.5 0.0 1.9 2 0 0 2 2 2 0 Stage II sporulation protein E (SpoIIE) BPD_transp_2 PF02653.11 CDI74683.1 - 0.021 13.7 0.1 4.5 6.1 0.5 2.3 2 0 0 2 2 2 0 Branched-chain amino acid transport system / permease component OAD_gamma PF04277.8 CDI74683.1 - 2.6 8.5 0.0 2.6 8.5 0.0 4.9 4 1 1 5 5 5 0 Oxaloacetate decarboxylase, gamma chain PRA1 PF03208.14 CDI74684.1 - 0.044 13.1 1.0 0.14 11.4 0.7 1.9 1 0 0 1 1 1 0 PRA1 family protein DUF3357 PF11837.3 CDI74684.1 - 0.048 13.5 0.9 0.048 13.5 0.6 4.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3357) DUF1180 PF06679.7 CDI74684.1 - 0.45 10.3 6.2 0.63 9.9 4.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1180) EphA2_TM PF14575.1 CDI74684.1 - 2.7 8.4 0.0 2.7 8.4 0.0 5.1 1 1 1 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain MamL-1 PF09596.5 CDI74687.1 - 0.085 12.6 3.2 9.3 6.1 0.2 2.8 2 0 0 2 2 2 0 MamL-1 domain DUF4131 PF13567.1 CDI74687.1 - 0.087 12.2 4.1 2.1 7.7 0.2 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) Prefoldin PF02996.12 CDI74688.1 - 4.4e-17 61.8 6.5 6.6e-17 61.2 4.5 1.3 1 0 0 1 1 1 1 Prefoldin subunit DUF3509 PF12021.3 CDI74688.1 - 0.0055 16.4 1.1 0.008 15.9 0.1 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3509) TMPIT PF07851.8 CDI74688.1 - 0.45 9.5 8.3 0.037 13.0 0.3 2.0 1 1 0 2 2 2 0 TMPIT-like protein CENP-Q PF13094.1 CDI74688.1 - 0.55 10.2 12.0 3 7.8 1.3 2.2 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Cut12 PF11500.3 CDI74688.1 - 0.68 9.6 7.0 0.12 12.0 0.2 2.1 2 0 0 2 2 2 0 Spindle pole body formation-associated protein V_ATPase_I PF01496.14 CDI74688.1 - 0.92 7.2 3.4 1.1 6.9 2.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF3395 PF11875.3 CDI74688.1 - 1.2 8.7 6.7 1.1 8.9 2.3 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF3395) IKKbetaNEMObind PF12179.3 CDI74688.1 - 4.7 7.1 7.4 0.79 9.5 0.1 3.0 3 0 0 3 3 3 0 I-kappa-kinase-beta NEMO binding domain V-SNARE PF05008.10 CDI74688.1 - 8.4 6.6 10.4 2.9 8.1 1.1 2.3 2 0 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus Spc24 PF08286.6 CDI74688.1 - 9 6.0 8.0 2.3 7.9 0.5 2.2 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 DUF2325 PF10087.4 CDI74689.1 - 0.09 12.6 0.1 0.19 11.5 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2325) Cnd1 PF12717.2 CDI74690.1 - 1.6e-06 28.0 0.1 4.9e-05 23.2 0.1 3.5 2 1 2 4 4 2 2 non-SMC mitotic condensation complex subunit 1 Ycf1 PF05758.7 CDI74690.1 - 0.00041 18.2 12.1 0.025 12.2 0.5 2.0 2 0 0 2 2 2 2 Ycf1 SPX PF03105.14 CDI74690.1 - 0.00057 19.7 13.3 0.0093 15.7 0.7 2.3 2 0 0 2 2 2 2 SPX domain FimP PF09766.4 CDI74690.1 - 0.0017 17.5 6.9 0.0017 17.5 4.8 2.4 2 1 0 2 2 1 1 Fms-interacting protein Gag_spuma PF03276.9 CDI74690.1 - 0.0028 16.0 15.8 0.0028 16.0 11.0 3.4 2 1 0 3 3 1 1 Spumavirus gag protein Suf PF05843.9 CDI74690.1 - 0.0035 17.0 26.6 0.036 13.8 4.5 2.4 2 0 0 2 2 2 2 Suppressor of forked protein (Suf) Dynamin_N PF00350.18 CDI74690.1 - 0.0038 17.0 8.6 0.12 12.2 1.0 2.2 2 0 0 2 2 2 2 Dynamin family DDHD PF02862.12 CDI74690.1 - 0.031 14.0 16.1 0.32 10.7 2.0 2.4 2 0 0 2 2 2 0 DDHD domain Fapy_DNA_glyco PF01149.19 CDI74690.1 - 0.041 14.2 0.6 0.18 12.1 0.2 1.9 1 1 1 2 2 2 0 Formamidopyrimidine-DNA glycosylase N-terminal domain Spore_YhcN_YlaJ PF09580.5 CDI74690.1 - 0.043 13.9 14.6 0.8 9.7 2.9 2.3 2 0 0 2 2 2 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) Raftlin PF15250.1 CDI74690.1 - 0.058 11.9 16.5 0.24 9.9 1.5 2.1 2 0 0 2 2 2 0 Raftlin Peptidase_S49_N PF08496.5 CDI74690.1 - 0.16 11.7 18.8 0.17 11.6 4.6 2.3 2 0 0 2 2 2 0 Peptidase family S49 N-terminal SGT1 PF07093.6 CDI74690.1 - 0.18 10.1 23.6 0.58 8.4 9.2 2.1 2 0 0 2 2 2 0 SGT1 protein Band_3_cyto PF07565.8 CDI74690.1 - 0.26 10.7 24.3 0.94 8.9 3.9 2.3 2 0 0 2 2 2 0 Band 3 cytoplasmic domain Plasmodium_Vir PF05795.6 CDI74690.1 - 0.41 9.8 4.9 1.2 8.2 0.2 2.1 2 0 0 2 2 2 0 Plasmodium vivax Vir protein Alg14 PF08660.6 CDI74690.1 - 0.7 9.8 9.3 0.49 10.3 1.1 2.6 2 1 0 2 2 2 0 Oligosaccharide biosynthesis protein Alg14 like SAGA-Tad1 PF12767.2 CDI74690.1 - 0.92 9.1 29.9 1.3 8.6 5.9 2.4 2 0 0 2 2 2 0 Transcriptional regulator of RNA polII, SAGA, subunit Exonuc_VII_L PF02601.10 CDI74690.1 - 0.95 8.5 25.3 2.1 7.4 2.1 2.4 2 0 0 2 2 2 0 Exonuclease VII, large subunit Serinc PF03348.10 CDI74690.1 - 1 7.9 18.8 0.067 11.9 0.9 2.3 2 0 0 2 2 2 0 Serine incorporator (Serinc) FAM176 PF14851.1 CDI74690.1 - 1.1 8.9 12.7 3.6 7.2 1.0 2.5 2 0 0 2 2 2 0 FAM176 family Otopetrin PF03189.8 CDI74690.1 - 1.2 8.1 8.9 4.3 6.2 0.2 2.1 2 0 0 2 2 2 0 Otopetrin Hid1 PF12722.2 CDI74690.1 - 1.5 6.4 22.4 0.48 8.0 2.6 2.1 2 0 0 2 2 2 0 High-temperature-induced dauer-formation protein DUF1510 PF07423.6 CDI74690.1 - 1.9 7.7 24.4 3.6 6.9 5.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) Gti1_Pac2 PF09729.4 CDI74690.1 - 2.2 8.1 14.6 0.5 10.2 0.3 2.4 2 0 0 2 2 2 0 Gti1/Pac2 family V_ATPase_I PF01496.14 CDI74690.1 - 2.3 5.9 20.9 2 6.1 2.0 2.1 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family CRF1 PF10380.4 CDI74690.1 - 3.2 8.0 17.0 2.1 8.6 1.5 2.8 3 0 0 3 3 2 0 Transcription factor CRF1 EPL1 PF10513.4 CDI74690.1 - 3.3 7.9 20.7 1.3 9.2 2.6 2.6 2 0 0 2 2 2 0 Enhancer of polycomb-like Spore_coat_CotO PF14153.1 CDI74690.1 - 3.9 6.8 35.5 0.89 8.9 5.8 2.3 2 0 0 2 2 2 0 Spore coat protein CotO Tim54 PF11711.3 CDI74690.1 - 5.2 5.5 15.2 2 6.8 1.0 2.5 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 AAA_23 PF13476.1 CDI74690.1 - 5.2 7.3 42.8 1.4 9.1 15.8 2.2 2 0 0 2 2 2 0 AAA domain LMBR1 PF04791.11 CDI74690.1 - 6.6 5.2 8.8 3.2 6.2 0.7 2.1 2 0 0 2 2 2 0 LMBR1-like membrane protein HlyD_2 PF12700.2 CDI74690.1 - 8 5.5 26.4 0.93 8.5 6.6 2.2 2 0 0 2 2 2 0 HlyD family secretion protein DUF4355 PF14265.1 CDI74690.1 - 8.4 6.3 39.5 6 6.8 12.5 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4355) Mucin PF01456.12 CDI74691.1 - 7.9e-06 25.7 8.1 7.9e-06 25.7 5.6 2.3 2 0 0 2 2 2 1 Mucin-like glycoprotein Cohesin_HEAT PF12765.2 CDI74691.1 - 0.00037 20.3 1.7 0.068 13.1 0.8 2.6 2 0 0 2 2 2 2 HEAT repeat associated with sister chromatid cohesion DUF2435 PF10363.4 CDI74691.1 - 0.0086 15.9 1.5 0.031 14.1 0.9 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF2435) NMDAR2_C PF10565.4 CDI74691.1 - 0.021 13.5 9.0 0.043 12.4 6.2 1.4 1 1 0 1 1 1 0 N-methyl D-aspartate receptor 2B3 C-terminus Herpes_capsid PF06112.6 CDI74691.1 - 0.61 10.1 13.8 1.3 9.0 5.0 2.5 2 0 0 2 2 2 0 Gammaherpesvirus capsid protein Hid1 PF12722.2 CDI74691.1 - 4.1 4.9 7.7 7.7 4.0 5.4 1.4 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Dicty_REP PF05086.7 CDI74691.1 - 8.4 4.0 5.5 12 3.5 3.8 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein CDK2AP PF09806.4 CDI74692.1 - 0.0038 17.4 6.6 0.0043 17.3 4.6 1.1 1 0 0 1 1 1 1 Cyclin-dependent kinase 2-associated protein Med15 PF09606.5 CDI74692.1 - 0.0088 14.3 12.4 0.008 14.4 8.6 1.1 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal 7tm_2 PF00002.19 CDI74692.1 - 0.029 13.4 0.9 0.031 13.3 0.6 1.1 1 0 0 1 1 1 0 7 transmembrane receptor (Secretin family) DUF1738 PF08401.6 CDI74692.1 - 0.035 13.8 0.2 0.045 13.4 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1738) DUF572 PF04502.8 CDI74692.1 - 0.13 11.4 3.7 0.16 11.1 2.5 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) SoxE PF06525.6 CDI74692.1 - 0.14 11.3 3.2 0.21 10.8 2.2 1.2 1 0 0 1 1 1 0 Sulfocyanin (SoxE) MACPF PF01823.14 CDI74692.1 - 0.32 10.6 5.5 0.36 10.4 3.8 1.1 1 0 0 1 1 1 0 MAC/Perforin domain Mlf1IP PF10248.4 CDI74692.1 - 0.39 10.3 5.3 0.43 10.1 3.7 1.1 1 0 0 1 1 1 0 Myelodysplasia-myeloid leukemia factor 1-interacting protein DUF2489 PF10675.4 CDI74692.1 - 0.48 10.1 8.4 0.64 9.7 5.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2489) Conotoxin PF02950.12 CDI74692.1 - 5.5 7.8 7.6 6.5 7.6 2.0 2.2 1 1 1 2 2 2 0 Conotoxin Spt20 PF12090.3 CDI74692.1 - 5.6 6.2 10.3 4.4 6.5 6.5 1.4 1 1 0 1 1 1 0 Spt20 family DUF912 PF06024.7 CDI74692.1 - 8.4 6.5 6.7 2.3 8.3 1.9 1.9 1 1 1 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Ni_hydr_CYTB PF01292.15 CDI74693.1 - 0.0066 15.8 1.2 0.0093 15.3 0.3 1.7 1 1 1 2 2 2 1 Prokaryotic cytochrome b561 YjgP_YjgQ PF03739.9 CDI74693.1 - 4.7 5.8 7.4 7.4 5.2 5.2 1.3 1 0 0 1 1 1 0 Predicted permease YjgP/YjgQ family Patched PF02460.13 CDI74693.1 - 8 4.2 6.3 15 3.3 4.4 1.4 1 0 0 1 1 1 0 Patched family PAT1 PF09770.4 CDI74696.1 - 0.0016 16.7 73.1 0.0016 16.7 50.7 2.4 2 0 0 2 2 2 1 Topoisomerase II-associated protein PAT1 BRF1 PF07741.8 CDI74697.1 - 0.014 15.5 0.8 0.64 10.2 0.8 2.6 2 0 0 2 2 2 0 Brf1-like TBP-binding domain FCP1_C PF09309.5 CDI74697.1 - 0.99 8.6 14.3 0.033 13.5 3.1 2.4 2 0 0 2 2 2 0 FCP1, C-terminal Pex16 PF08610.5 CDI74697.1 - 4.9 6.0 6.5 5.4 5.9 2.3 2.2 2 0 0 2 2 2 0 Peroxisomal membrane protein (Pex16) Serinc PF03348.10 CDI74697.1 - 5.5 5.5 5.4 6.1 5.4 2.1 2.0 2 0 0 2 2 2 0 Serine incorporator (Serinc) NUDE_C PF04880.8 CDI74700.1 - 0.088 13.1 6.6 0.1 12.9 4.5 1.1 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region DUF677 PF05055.7 CDI74700.1 - 0.29 9.7 4.6 0.35 9.4 3.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF677) Gag_spuma PF03276.9 CDI74700.1 - 0.52 8.5 6.1 0.58 8.4 4.3 1.0 1 0 0 1 1 1 0 Spumavirus gag protein GSK-3_bind PF05350.7 CDI74700.1 - 3.2 7.1 12.1 3.6 6.9 8.4 1.1 1 0 0 1 1 1 0 Glycogen synthase kinase-3 binding FimP PF09766.4 CDI74701.1 - 0.0021 17.1 12.8 0.0021 17.1 8.9 2.8 3 0 0 3 3 3 2 Fms-interacting protein DUF2076 PF09849.4 CDI74701.1 - 0.003 17.6 19.5 0.003 17.6 13.5 3.7 3 1 0 3 3 1 1 Uncharacterized protein conserved in bacteria (DUF2076) DUF4207 PF13904.1 CDI74701.1 - 0.0053 16.1 2.4 0.0053 16.1 1.7 3.5 3 0 0 3 3 3 1 Domain of unknown function (DUF4207) Pex14_N PF04695.8 CDI74701.1 - 0.014 15.4 13.9 0.014 15.4 9.6 4.0 3 1 0 3 3 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region TPR_8 PF13181.1 CDI74701.1 - 0.025 14.3 13.5 0.2 11.4 1.5 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat Gti1_Pac2 PF09729.4 CDI74701.1 - 0.1 12.4 11.6 0.18 11.6 2.6 3.1 3 0 0 3 3 3 0 Gti1/Pac2 family Suf PF05843.9 CDI74701.1 - 0.39 10.3 22.2 0.03 14.0 6.4 3.1 3 0 0 3 3 3 0 Suppressor of forked protein (Suf) Med15 PF09606.5 CDI74701.1 - 1.4 7.0 77.3 0.39 8.8 8.6 3.1 3 0 0 3 3 3 0 ARC105 or Med15 subunit of Mediator complex non-fungal Afi1 PF07792.7 CDI74701.1 - 1.5 8.7 17.7 0.14 12.1 4.3 3.2 3 0 0 3 3 3 0 Docking domain of Afi1 for Arf3 in vesicle trafficking DUF912 PF06024.7 CDI74701.1 - 2.3 8.2 14.0 0.32 11.0 3.0 3.3 3 0 0 3 3 3 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Apc15p PF05841.6 CDI74701.1 - 3.3 8.4 28.2 0.096 13.4 5.8 3.7 3 0 0 3 3 3 0 Apc15p protein Sporozoite_P67 PF05642.6 CDI74701.1 - 5 4.8 9.8 0.18 9.6 0.6 2.3 2 0 0 2 2 2 0 Sporozoite P67 surface antigen TCP PF03634.8 CDI74701.1 - 5.5 7.3 32.4 0.49 10.7 4.7 3.9 4 0 0 4 4 4 0 TCP family transcription factor CPSF100_C PF13299.1 CDI74701.1 - 6.1 7.0 16.9 0.31 11.2 3.9 3.1 3 0 0 3 3 3 0 Cleavage and polyadenylation factor 2 C-terminal Band_3_cyto PF07565.8 CDI74701.1 - 8.2 5.8 22.2 4.2 6.7 7.4 3.3 3 0 0 3 3 3 0 Band 3 cytoplasmic domain GRA6 PF05084.8 CDI74702.1 - 0.0074 15.8 5.8 0.0081 15.7 4.0 1.0 1 0 0 1 1 1 1 Granule antigen protein (GRA6) Suf PF05843.9 CDI74702.1 - 0.061 13.0 15.8 0.066 12.9 11.0 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Bac_luciferase PF00296.15 CDI74702.1 - 0.094 11.8 9.7 0.11 11.5 6.7 1.1 1 0 0 1 1 1 0 Luciferase-like monooxygenase FimP PF09766.4 CDI74702.1 - 0.096 11.7 16.4 0.1 11.6 11.4 1.1 1 0 0 1 1 1 0 Fms-interacting protein Presenilin PF01080.12 CDI74702.1 - 0.11 11.2 5.8 0.13 11.0 4.0 1.1 1 0 0 1 1 1 0 Presenilin Paf1 PF03985.8 CDI74702.1 - 0.14 10.8 7.7 0.15 10.7 5.4 1.1 1 0 0 1 1 1 0 Paf1 Neur_chan_memb PF02932.11 CDI74702.1 - 0.16 11.8 4.2 0.19 11.5 2.9 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF3987 PF13148.1 CDI74702.1 - 0.19 10.2 10.2 0.24 9.9 7.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) Peptidase_C58 PF03543.9 CDI74702.1 - 0.37 10.2 15.6 0.43 10.0 10.8 1.1 1 0 0 1 1 1 0 Yersinia/Haemophilus virulence surface antigen DcuC PF03606.10 CDI74702.1 - 0.4 8.8 2.4 0.49 8.5 1.7 1.1 1 0 0 1 1 1 0 C4-dicarboxylate anaerobic carrier Gag_spuma PF03276.9 CDI74702.1 - 0.69 8.1 19.3 0.71 8.1 13.4 1.2 1 0 0 1 1 1 0 Spumavirus gag protein eIF-3_zeta PF05091.7 CDI74702.1 - 0.9 8.0 11.1 0.89 8.0 7.7 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DDHD PF02862.12 CDI74702.1 - 1 9.1 6.7 1.1 8.9 4.6 1.2 1 0 0 1 1 1 0 DDHD domain Hid1 PF12722.2 CDI74702.1 - 1.2 6.7 6.0 1.2 6.7 4.1 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Conotoxin PF02950.12 CDI74702.1 - 1.3 9.9 13.8 0.5 11.2 0.3 2.3 2 0 0 2 2 2 0 Conotoxin DUF913 PF06025.7 CDI74702.1 - 1.5 7.5 5.0 1.6 7.4 3.5 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DUF4228 PF14009.1 CDI74702.1 - 1.5 8.8 9.8 2 8.5 6.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4228) vMSA PF00695.14 CDI74702.1 - 1.7 7.7 6.8 2 7.5 4.7 1.2 1 0 0 1 1 1 0 Major surface antigen from hepadnavirus FLO_LFY PF01698.11 CDI74702.1 - 2.4 6.9 11.3 2.6 6.8 7.8 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein Med15 PF09606.5 CDI74702.1 - 2.7 6.0 47.7 3.3 5.7 33.1 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF4557 PF15101.1 CDI74702.1 - 5.2 6.8 25.1 6.9 6.4 17.1 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4557) DUF4134 PF13572.1 CDI74702.1 - 8.6 6.5 7.6 6.3 6.9 4.2 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4134) SprA-related PF12118.3 CDI74703.1 - 2.9e-05 23.5 42.2 2.9e-05 23.5 29.2 2.2 2 0 0 2 2 2 1 SprA-related family DUF605 PF04652.11 CDI74703.1 - 0.00029 20.3 28.0 0.00037 20.0 19.4 1.2 1 0 0 1 1 1 1 Vta1 like Cwf_Cwc_15 PF04889.7 CDI74703.1 - 0.0049 16.6 19.0 0.009 15.7 13.2 1.5 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein AAA_23 PF13476.1 CDI74703.1 - 0.008 16.5 10.4 0.011 16.1 7.2 1.3 1 0 0 1 1 1 1 AAA domain SOBP PF15279.1 CDI74703.1 - 0.037 14.4 34.4 0.056 13.8 23.9 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein RR_TM4-6 PF06459.7 CDI74703.1 - 0.84 9.4 14.1 1.4 8.7 9.8 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Utp14 PF04615.8 CDI74703.1 - 3.2 5.7 27.8 4 5.4 19.2 1.1 1 0 0 1 1 1 0 Utp14 protein Tuberin PF03542.11 CDI74703.1 - 6.4 5.7 10.5 12 4.8 7.3 1.5 1 0 0 1 1 1 0 Tuberin Activator_LAG-3 PF11498.3 CDI74703.1 - 8.6 4.9 51.6 0.0097 14.6 27.3 2.1 2 0 0 2 2 2 0 Transcriptional activator LAG-3 WBP-1 PF11669.3 CDI74704.1 - 0.35 10.9 12.1 1.3 9.1 1.6 3.3 3 0 0 3 3 3 0 WW domain-binding protein 1 Spt20 PF12090.3 CDI74704.1 - 0.57 9.5 9.9 1.1 8.5 1.1 3.3 3 0 0 3 3 3 0 Spt20 family SPX PF03105.14 CDI74704.1 - 1.1 8.9 16.8 0.32 10.7 6.7 2.8 2 1 0 2 2 2 0 SPX domain Activator_LAG-3 PF11498.3 CDI74706.1 - 0.0027 16.5 16.5 0.0027 16.5 11.4 3.2 2 1 1 3 3 1 1 Transcriptional activator LAG-3 DUF755 PF05501.6 CDI74706.1 - 0.0081 16.2 21.1 0.0081 16.2 14.6 3.3 2 1 1 3 3 1 1 Domain of unknown function (DUF755) Band_3_cyto PF07565.8 CDI74706.1 - 0.017 14.6 26.4 0.12 11.9 0.6 2.2 2 0 0 2 2 2 0 Band 3 cytoplasmic domain PAT1 PF09770.4 CDI74706.1 - 0.039 12.2 81.8 0.011 14.0 30.9 3.0 3 0 0 3 3 3 0 Topoisomerase II-associated protein PAT1 SPX PF03105.14 CDI74706.1 - 0.047 13.4 25.1 0.23 11.2 10.6 2.1 2 0 0 2 2 2 0 SPX domain Spore_YhcN_YlaJ PF09580.5 CDI74706.1 - 0.058 13.5 17.0 0.16 12.0 8.8 2.3 2 0 0 2 2 2 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) Neur_chan_memb PF02932.11 CDI74706.1 - 0.18 11.6 26.8 1.4 8.7 10.4 2.2 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Suf PF05843.9 CDI74706.1 - 0.28 10.8 41.4 0.071 12.8 17.4 2.4 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) GAGA_bind PF06217.7 CDI74706.1 - 0.33 10.8 21.0 0.056 13.4 7.8 2.2 2 0 0 2 2 2 0 GAGA binding protein-like family SRP-alpha_N PF04086.8 CDI74706.1 - 0.4 10.0 30.5 1.2 8.4 3.1 2.2 2 0 0 2 2 2 0 Signal recognition particle, alpha subunit, N-terminal SAGA-Tad1 PF12767.2 CDI74706.1 - 0.83 9.2 36.6 1.2 8.7 14.9 2.4 2 0 0 2 2 2 0 Transcriptional regulator of RNA polII, SAGA, subunit DUF1510 PF07423.6 CDI74706.1 - 1 8.6 29.5 0.043 13.1 12.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) Hid1 PF12722.2 CDI74706.1 - 1.3 6.5 30.4 0.029 12.0 10.6 2.0 2 0 0 2 2 2 0 High-temperature-induced dauer-formation protein Zip PF02535.17 CDI74706.1 - 1.4 7.8 7.4 1.6 7.6 3.1 2.2 2 0 0 2 2 2 0 ZIP Zinc transporter CDC45 PF02724.9 CDI74706.1 - 2.1 6.2 26.0 0.063 11.3 11.0 2.1 2 0 0 2 2 2 0 CDC45-like protein Cwf_Cwc_15 PF04889.7 CDI74706.1 - 2.3 7.8 28.7 3.3 7.3 12.3 2.2 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein DUF3260 PF11658.3 CDI74706.1 - 2.8 5.9 21.0 0.71 7.9 9.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3260) Spore_coat_CotO PF14153.1 CDI74706.1 - 3 7.2 42.1 0.32 10.4 19.2 2.2 2 0 0 2 2 2 0 Spore coat protein CotO PLRV_ORF5 PF01690.12 CDI74706.1 - 3.1 6.8 24.9 3.5 6.6 10.7 2.2 2 0 0 2 2 2 0 Potato leaf roll virus readthrough protein SOBP PF15279.1 CDI74706.1 - 3.2 8.0 38.0 0.018 15.4 8.8 2.5 2 1 0 2 2 2 0 Sine oculis-binding protein Ofd1_CTDD PF10637.4 CDI74706.1 - 3.8 6.5 21.6 0.35 9.9 7.2 2.2 2 0 0 2 2 2 0 Oxoglutarate and iron-dependent oxygenase degradation C-term FAM60A PF15396.1 CDI74706.1 - 7.4 6.2 28.3 1.7 8.3 10.9 2.2 2 0 0 2 2 2 0 Protein Family FAM60A AAA_11 PF13086.1 CDI74706.1 - 7.4 6.0 33.0 0.027 14.0 12.7 2.2 1 1 0 2 2 2 0 AAA domain Ycf1 PF05758.7 CDI74706.1 - 7.8 4.0 24.5 1.1 6.8 11.6 2.0 2 0 0 2 2 2 0 Ycf1 NARP1 PF12569.3 CDI74706.1 - 8.5 5.0 24.2 0.67 8.6 10.5 2.1 2 0 0 2 2 2 0 NMDA receptor-regulated protein 1 Raftlin PF15250.1 CDI74706.1 - 9.2 4.6 24.9 0.5 8.8 10.4 2.1 2 0 0 2 2 2 0 Raftlin fn3 PF00041.16 CDI74710.1 - 0.067 13.3 0.0 0.087 12.9 0.0 1.2 1 0 0 1 1 1 0 Fibronectin type III domain Dynamin_M PF01031.15 CDI74711.1 - 1.8e-72 243.6 0.3 9.8e-72 241.2 0.1 2.0 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.18 CDI74711.1 - 1.4e-36 125.8 0.0 4.2e-36 124.3 0.0 1.8 2 0 0 2 2 2 1 Dynamin family GED PF02212.13 CDI74711.1 - 1.4e-21 76.1 0.1 4.6e-21 74.5 0.1 2.0 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 CDI74711.1 - 0.024 14.5 0.0 0.12 12.3 0.0 2.2 1 1 0 1 1 1 0 50S ribosome-binding GTPase Miro PF08477.8 CDI74711.1 - 0.048 14.1 0.1 0.26 11.8 0.1 2.3 1 1 1 2 2 2 0 Miro-like protein EF_TS PF00889.14 CDI74713.1 - 1.3e-33 116.1 0.5 1.9e-32 112.3 0.2 2.1 1 1 1 2 2 2 2 Elongation factor TS PS_Dcarbxylase PF02666.10 CDI74714.1 - 4.5e-07 29.3 0.0 7.6e-07 28.6 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase Ycf1 PF05758.7 CDI74715.1 - 0.0015 16.3 5.8 0.0015 16.3 4.0 2.2 2 0 0 2 2 2 2 Ycf1 Spore_coat_CotO PF14153.1 CDI74715.1 - 0.0021 17.5 15.9 0.0021 17.5 11.0 3.8 5 0 0 5 5 5 1 Spore coat protein CotO ubiquitin PF00240.18 CDI74716.1 - 4.5e-12 45.1 1.2 4.5e-12 45.1 0.8 2.0 1 1 1 2 2 1 1 Ubiquitin family Rad60-SLD PF11976.3 CDI74716.1 - 2.6e-05 23.7 0.1 2.6e-05 23.7 0.1 2.1 1 1 1 2 2 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 CDI74716.1 - 0.00025 21.1 3.4 0.00025 21.1 2.4 1.5 2 0 0 2 2 1 1 DUF2407 ubiquitin-like domain DUF4246 PF14033.1 CDI74716.1 - 0.0069 15.0 2.8 0.0076 14.9 1.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) Plasmodium_Vir PF05795.6 CDI74716.1 - 0.0087 15.3 1.7 0.0096 15.1 1.2 1.1 1 0 0 1 1 1 1 Plasmodium vivax Vir protein Cwf_Cwc_15 PF04889.7 CDI74716.1 - 0.009 15.7 9.1 0.012 15.3 6.3 1.1 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein FimP PF09766.4 CDI74716.1 - 0.012 14.7 10.0 0.015 14.4 7.0 1.3 1 0 0 1 1 1 0 Fms-interacting protein Med15 PF09606.5 CDI74716.1 - 0.014 13.6 25.1 0.015 13.5 17.4 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Ubiquitin_2 PF14560.1 CDI74716.1 - 0.024 14.8 3.0 0.077 13.2 2.1 2.0 1 1 0 1 1 1 0 Ubiquitin-like domain Sporozoite_P67 PF05642.6 CDI74716.1 - 0.051 11.4 3.2 0.053 11.3 2.2 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen CDK2AP PF09806.4 CDI74716.1 - 0.056 13.6 12.4 0.092 12.9 8.6 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein DUF572 PF04502.8 CDI74716.1 - 0.077 12.2 8.5 0.095 11.8 5.9 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Lin-8 PF03353.10 CDI74716.1 - 0.085 12.1 8.8 0.1 11.8 6.1 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist PAT1 PF09770.4 CDI74716.1 - 0.14 10.3 17.7 0.16 10.2 12.3 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 FliD_N PF02465.13 CDI74716.1 - 0.15 12.4 11.7 0.36 11.2 8.1 1.6 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 N-terminus FRQ PF09421.5 CDI74716.1 - 0.36 8.5 11.7 0.41 8.3 8.1 1.1 1 0 0 1 1 1 0 Frequency clock protein DUF4175 PF13779.1 CDI74716.1 - 0.46 8.1 23.9 0.49 8.0 16.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) DUF2217 PF10265.4 CDI74716.1 - 0.48 9.1 8.8 0.55 8.9 6.1 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) DUF3280 PF11684.3 CDI74716.1 - 0.48 10.6 5.9 0.76 9.9 4.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2380) BRF1 PF07741.8 CDI74716.1 - 0.84 9.8 9.7 1.1 9.4 6.6 1.5 1 1 0 1 1 1 0 Brf1-like TBP-binding domain RR_TM4-6 PF06459.7 CDI74716.1 - 0.87 9.4 5.8 1.2 9.0 4.0 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DNA_pol_viral_N PF00242.12 CDI74716.1 - 1.3 7.9 17.0 1.6 7.6 11.8 1.0 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain SLD3 PF08639.5 CDI74716.1 - 2.1 6.8 14.8 2.5 6.6 10.2 1.1 1 0 0 1 1 1 0 DNA replication regulator SLD3 Apt1 PF10351.4 CDI74716.1 - 2.5 6.8 8.9 3.2 6.5 6.2 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF912 PF06024.7 CDI74716.1 - 2.7 8.0 7.2 6.3 6.9 3.7 2.0 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Pex16 PF08610.5 CDI74716.1 - 2.8 6.8 7.2 3.8 6.4 5.0 1.2 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) TraG-D_C PF12696.2 CDI74716.1 - 3.3 7.5 11.6 1.4 8.7 0.7 2.3 2 0 0 2 2 2 0 TraM recognition site of TraD and TraG Neur_chan_memb PF02932.11 CDI74716.1 - 3.4 7.5 6.7 4.5 7.1 4.6 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region RAP1 PF07218.6 CDI74716.1 - 3.5 5.6 8.3 4.3 5.3 5.8 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DUF4407 PF14362.1 CDI74716.1 - 3.7 6.4 8.6 4.2 6.2 5.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Hid1 PF12722.2 CDI74716.1 - 5.4 4.5 12.6 7.5 4.0 8.7 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Band_3_cyto PF07565.8 CDI74716.1 - 6.7 6.1 12.7 8.9 5.7 8.8 1.2 1 1 0 1 1 1 0 Band 3 cytoplasmic domain AAA_23 PF13476.1 CDI74716.1 - 7.1 6.8 10.3 10 6.3 7.1 1.3 1 0 0 1 1 1 0 AAA domain Band_3_cyto PF07565.8 CDI74718.1 - 0.18 11.3 6.0 0.35 10.3 4.1 1.5 1 1 0 1 1 1 0 Band 3 cytoplasmic domain PAPA-1 PF04795.7 CDI74718.1 - 1.6 9.5 13.7 0.12 13.0 1.5 2.3 2 0 0 2 2 2 0 PAPA-1-like conserved region TFIIA PF03153.8 CDI74718.1 - 2.4 7.9 19.2 2.8 7.7 13.3 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Baculo_PP31 PF05311.6 CDI74718.1 - 3.8 6.7 7.4 1.6 7.9 1.0 2.0 2 0 0 2 2 2 0 Baculovirus 33KDa late protein (PP31) FimP PF09766.4 CDI74718.1 - 7.2 5.5 13.6 0.041 12.9 2.3 1.9 2 0 0 2 2 2 0 Fms-interacting protein Pkinase PF00069.20 CDI74719.1 - 1.1e-05 24.7 0.0 3.1e-05 23.2 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.1 CDI74719.1 - 0.00046 19.2 0.0 0.0011 17.9 0.0 1.6 1 0 0 1 1 1 1 Kinase-like DUF1365 PF07103.6 CDI74719.1 - 0.0025 16.8 3.8 0.3 10.0 1.2 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF1365) Herpes_UL87 PF03043.9 CDI74719.1 - 0.03 12.7 0.0 1.2 7.4 0.0 2.5 1 1 0 1 1 1 0 Herpesvirus UL87 family Med15 PF09606.5 CDI74719.1 - 0.61 8.2 60.3 0.089 10.9 30.8 2.6 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal ABC1 PF03109.11 CDI74720.1 - 3.2e-05 23.8 3.8 5e-05 23.2 2.6 1.3 1 0 0 1 1 1 1 ABC1 family FimP PF09766.4 CDI74720.1 - 0.00048 19.3 16.2 0.00058 19.0 11.2 1.1 1 0 0 1 1 1 1 Fms-interacting protein APG6 PF04111.7 CDI74720.1 - 0.0038 16.3 7.2 0.0038 16.3 5.0 1.1 1 0 0 1 1 1 1 Autophagy protein Apg6 Suf PF05843.9 CDI74720.1 - 0.0041 16.8 10.2 0.0046 16.7 7.0 1.1 1 0 0 1 1 1 1 Suppressor of forked protein (Suf) Med15 PF09606.5 CDI74720.1 - 0.0063 14.7 32.2 0.0064 14.7 22.3 1.1 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal TFIIA PF03153.8 CDI74720.1 - 0.0071 16.2 17.6 0.0075 16.2 12.2 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit DUF2422 PF10337.4 CDI74720.1 - 0.0095 14.7 9.9 0.012 14.3 6.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2422) SelP_N PF04592.9 CDI74720.1 - 0.01 15.2 10.3 0.014 14.7 7.2 1.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region DUF3987 PF13148.1 CDI74720.1 - 0.011 14.2 3.9 0.013 14.1 2.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) SprA-related PF12118.3 CDI74720.1 - 0.011 15.0 26.8 0.012 14.9 18.6 1.1 1 0 0 1 1 1 0 SprA-related family DUF4557 PF15101.1 CDI74720.1 - 0.015 15.1 13.9 0.016 15.0 9.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) HD-ZIP_N PF04618.7 CDI74720.1 - 0.017 15.6 2.0 0.022 15.3 1.4 1.2 1 0 0 1 1 1 0 HD-ZIP protein N terminus DUF912 PF06024.7 CDI74720.1 - 0.02 14.9 2.6 0.031 14.3 1.8 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF2072 PF09845.4 CDI74720.1 - 0.024 14.5 5.1 0.033 14.0 3.5 1.4 1 0 0 1 1 1 0 Zn-ribbon containing protein (DUF2072) AAA_23 PF13476.1 CDI74720.1 - 0.027 14.7 9.6 0.029 14.7 6.7 1.1 1 0 0 1 1 1 0 AAA domain PAT1 PF09770.4 CDI74720.1 - 0.035 12.3 24.1 0.036 12.3 16.7 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 RR_TM4-6 PF06459.7 CDI74720.1 - 0.05 13.4 9.0 0.056 13.3 6.2 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 AIF_C PF14721.1 CDI74720.1 - 0.051 13.8 6.9 0.072 13.3 4.8 1.2 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Raftlin PF15250.1 CDI74720.1 - 0.054 12.0 7.4 0.057 11.9 5.2 1.1 1 0 0 1 1 1 0 Raftlin Pro_CA PF00484.14 CDI74720.1 - 0.056 13.4 2.5 0.071 13.1 1.7 1.2 1 0 0 1 1 1 0 Carbonic anhydrase Spc7_N PF15402.1 CDI74720.1 - 0.062 11.3 9.2 0.071 11.1 6.4 1.0 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 FNIP_N PF14636.1 CDI74720.1 - 0.082 13.3 9.3 0.1 13.0 6.5 1.1 1 0 0 1 1 1 0 Folliculin-interacting protein N-terminus YABBY PF04690.8 CDI74720.1 - 0.097 12.9 6.2 0.14 12.3 4.3 1.2 1 0 0 1 1 1 0 YABBY protein NPR3 PF03666.8 CDI74720.1 - 0.1 11.0 6.7 0.12 10.9 4.7 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 GNT-I PF03071.10 CDI74720.1 - 0.11 11.0 5.3 0.12 10.8 3.7 1.1 1 0 0 1 1 1 0 GNT-I family RIC3 PF15361.1 CDI74720.1 - 0.12 12.5 8.5 0.18 12.0 5.9 1.3 1 0 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 Paf1 PF03985.8 CDI74720.1 - 0.13 10.9 11.1 0.14 10.8 7.7 1.1 1 0 0 1 1 1 0 Paf1 DUF1800 PF08811.6 CDI74720.1 - 0.14 11.1 11.4 0.14 11.0 7.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1800) Spore_coat_CotO PF14153.1 CDI74720.1 - 0.15 11.5 16.2 0.21 11.0 11.2 1.2 1 0 0 1 1 1 0 Spore coat protein CotO Pal1 PF08316.6 CDI74720.1 - 0.15 12.5 3.0 0.18 12.2 2.1 1.2 1 0 0 1 1 1 0 Pal1 cell morphology protein Serinc PF03348.10 CDI74720.1 - 0.15 10.7 10.4 0.2 10.3 7.2 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) FHIPEP PF00771.15 CDI74720.1 - 0.17 10.1 6.8 0.21 9.8 4.7 1.1 1 0 0 1 1 1 0 FHIPEP family Band_3_cyto PF07565.8 CDI74720.1 - 0.18 11.2 9.8 0.21 11.0 6.8 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain DUF913 PF06025.7 CDI74720.1 - 0.18 10.5 4.6 0.18 10.4 3.2 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Baculo_PP31 PF05311.6 CDI74720.1 - 0.19 10.9 10.1 0.22 10.7 7.0 1.1 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) GOLD_2 PF13897.1 CDI74720.1 - 0.2 11.8 2.5 0.22 11.7 1.7 1.2 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking DUF3381 PF11861.3 CDI74720.1 - 0.21 11.0 10.0 0.24 10.8 6.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) DDHD PF02862.12 CDI74720.1 - 0.22 11.2 8.7 0.24 11.1 6.0 1.1 1 0 0 1 1 1 0 DDHD domain Dynamin_N PF00350.18 CDI74720.1 - 0.22 11.3 2.8 0.26 11.0 2.0 1.2 1 0 0 1 1 1 0 Dynamin family SUFU_C PF12470.3 CDI74720.1 - 0.25 10.9 5.1 0.31 10.6 3.5 1.1 1 0 0 1 1 1 0 Suppressor of Fused Gli/Ci N terminal binding domain DUF940 PF06082.6 CDI74720.1 - 0.28 9.6 5.8 0.29 9.6 4.0 1.0 1 0 0 1 1 1 0 Bacterial putative lipoprotein (DUF940) R_equi_Vir PF05526.6 CDI74720.1 - 0.3 10.7 4.3 0.36 10.4 3.0 1.2 1 0 0 1 1 1 0 Rhodococcus equi virulence-associated protein Tim54 PF11711.3 CDI74720.1 - 0.3 9.6 6.0 0.32 9.5 4.2 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 AUX_IAA PF02309.11 CDI74720.1 - 0.31 10.7 7.7 0.36 10.5 5.4 1.1 1 0 0 1 1 1 0 AUX/IAA family Ycf1 PF05758.7 CDI74720.1 - 0.32 8.6 7.9 0.35 8.5 5.5 1.0 1 0 0 1 1 1 0 Ycf1 DUF4011 PF13195.1 CDI74720.1 - 0.38 10.7 4.4 0.44 10.5 3.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4011) Zip PF02535.17 CDI74720.1 - 0.39 9.6 2.3 0.39 9.6 1.6 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter DUF2126 PF09899.4 CDI74720.1 - 0.4 8.6 5.3 0.43 8.5 3.7 1.1 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) DUF2229 PF09989.4 CDI74720.1 - 0.42 10.0 2.9 0.48 9.8 2.0 1.2 1 0 0 1 1 1 0 CoA enzyme activase uncharacterised domain (DUF2229) PH_4 PF15404.1 CDI74720.1 - 0.47 9.9 6.9 0.63 9.5 4.8 1.2 1 0 0 1 1 1 0 Pleckstrin homology domain CD20 PF04103.10 CDI74720.1 - 0.49 10.3 2.5 0.67 9.8 1.7 1.3 1 0 0 1 1 1 0 CD20-like family LIM_bind PF01803.11 CDI74720.1 - 0.5 9.4 11.6 0.6 9.1 8.0 1.1 1 0 0 1 1 1 0 LIM-domain binding protein CPSF100_C PF13299.1 CDI74720.1 - 0.51 10.5 6.9 0.58 10.3 4.8 1.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Hid1 PF12722.2 CDI74720.1 - 0.52 7.9 7.8 0.52 7.9 5.4 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Sec62 PF03839.11 CDI74720.1 - 0.56 9.5 4.2 0.63 9.4 2.9 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 GvpL_GvpF PF06386.6 CDI74720.1 - 0.6 9.6 10.3 0.76 9.3 7.2 1.2 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF DUF853 PF05872.7 CDI74720.1 - 0.61 8.3 7.5 0.63 8.3 5.2 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) DHHW PF14286.1 CDI74720.1 - 0.65 9.2 6.6 0.67 9.2 4.5 1.1 1 0 0 1 1 1 0 DHHW protein NARP1 PF12569.3 CDI74720.1 - 0.7 8.5 11.5 0.75 8.4 8.0 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Presenilin PF01080.12 CDI74720.1 - 0.74 8.5 6.1 0.79 8.4 4.2 1.1 1 0 0 1 1 1 0 Presenilin FLO_LFY PF01698.11 CDI74720.1 - 0.75 8.5 11.5 0.82 8.4 8.0 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein Folate_carrier PF01770.13 CDI74720.1 - 0.79 8.1 4.9 0.85 8.0 3.4 1.1 1 0 0 1 1 1 0 Reduced folate carrier Peptidase_S49_N PF08496.5 CDI74720.1 - 0.84 9.4 8.7 1.2 8.9 6.0 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Pox_P4B PF03292.9 CDI74720.1 - 0.99 7.2 6.0 1.1 7.0 4.1 1.0 1 0 0 1 1 1 0 Poxvirus P4B major core protein Gti1_Pac2 PF09729.4 CDI74720.1 - 1.1 9.0 5.5 1.4 8.7 3.8 1.2 1 0 0 1 1 1 0 Gti1/Pac2 family Ctr PF04145.10 CDI74720.1 - 1.4 8.9 5.5 2 8.4 3.8 1.3 1 0 0 1 1 1 0 Ctr copper transporter family EIIBC-GUT_N PF03612.9 CDI74720.1 - 1.4 8.4 9.8 1.9 8.0 6.8 1.2 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Neur_chan_memb PF02932.11 CDI74720.1 - 1.5 8.6 6.6 1.7 8.4 4.6 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region HAUS6_N PF14661.1 CDI74720.1 - 1.5 8.1 17.9 1.9 7.7 12.4 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus eIF_4EBP PF05456.6 CDI74720.1 - 1.6 8.4 10.9 2.2 7.9 7.3 1.3 1 1 0 1 1 1 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) Glyco_transf_15 PF01793.11 CDI74720.1 - 1.7 7.4 9.6 2.1 7.2 6.6 1.1 1 0 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase FCP1_C PF09309.5 CDI74720.1 - 1.8 7.7 12.0 2.7 7.2 8.3 1.3 1 0 0 1 1 1 0 FCP1, C-terminal FAM176 PF14851.1 CDI74720.1 - 1.9 8.1 6.1 2.8 7.5 4.2 1.3 1 0 0 1 1 1 0 FAM176 family DUF3450 PF11932.3 CDI74720.1 - 2 7.5 22.9 2.8 7.1 15.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Lig_chan PF00060.21 CDI74720.1 - 2 8.0 6.2 2.5 7.7 4.3 1.1 1 0 0 1 1 1 0 Ligand-gated ion channel HCO3_cotransp PF00955.16 CDI74720.1 - 2.4 6.7 4.6 2.8 6.5 3.2 1.0 1 0 0 1 1 1 0 HCO3- transporter family BTV_NS2 PF04514.7 CDI74720.1 - 2.5 6.8 11.0 3 6.6 7.6 1.0 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Glt_symporter PF03616.9 CDI74720.1 - 2.6 6.4 4.4 3.4 6.0 3.0 1.1 1 0 0 1 1 1 0 Sodium/glutamate symporter RED_N PF07808.8 CDI74720.1 - 2.6 7.1 17.1 3.7 6.7 11.9 1.2 1 0 0 1 1 1 0 RED-like protein N-terminal region Maf1 PF09174.5 CDI74720.1 - 2.6 7.8 6.7 3.1 7.6 4.6 1.1 1 0 0 1 1 1 0 Maf1 regulator OATP PF03137.15 CDI74720.1 - 2.7 5.9 9.6 3.3 5.6 6.7 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Cellulose_synt PF03552.9 CDI74720.1 - 3.2 5.9 7.0 3.7 5.7 4.8 1.1 1 0 0 1 1 1 0 Cellulose synthase Kei1 PF08552.6 CDI74720.1 - 3.3 7.3 10.1 4.6 6.8 7.0 1.1 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 FemAB PF02388.11 CDI74720.1 - 3.7 6.1 13.4 4.8 5.7 9.3 1.1 1 0 0 1 1 1 0 FemAB family Plasmodium_Vir PF05795.6 CDI74720.1 - 4.1 6.4 6.7 4.9 6.2 4.7 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein DUF4407 PF14362.1 CDI74720.1 - 4.2 6.2 17.2 4.8 6.0 11.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Paramyxo_ncap PF00973.14 CDI74720.1 - 4.3 5.9 6.5 4.5 5.8 4.5 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein DUF3584 PF12128.3 CDI74720.1 - 4.7 4.4 20.9 5.3 4.2 14.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Pex14_N PF04695.8 CDI74720.1 - 4.9 7.2 24.8 4.8 7.2 16.6 1.4 1 1 1 2 2 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF106 PF01956.11 CDI74720.1 - 4.9 6.6 9.0 6.5 6.2 6.2 1.1 1 0 0 1 1 1 0 Integral membrane protein DUF106 FYDLN_acid PF09538.5 CDI74720.1 - 4.9 7.7 13.9 2.5 8.7 8.3 1.5 1 1 1 2 2 1 0 Protein of unknown function (FYDLN_acid) RAB3GAP2_N PF14655.1 CDI74720.1 - 5.4 5.9 17.0 21 3.9 11.8 1.8 1 1 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus 5_nucleotid PF05761.9 CDI74720.1 - 5.4 5.4 8.5 7 5.0 5.9 1.1 1 0 0 1 1 1 0 5' nucleotidase family EIF4E-T PF10477.4 CDI74720.1 - 5.4 5.6 13.7 6 5.5 9.5 1.0 1 0 0 1 1 1 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E DUF4355 PF14265.1 CDI74720.1 - 5.5 6.9 23.6 8.2 6.4 16.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4355) Borrelia_P83 PF05262.6 CDI74720.1 - 6 5.0 14.1 6 5.0 9.8 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF4199 PF13858.1 CDI74720.1 - 7 6.5 9.4 10 6.0 6.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) DUF844 PF05815.6 CDI74720.1 - 7.1 5.3 10.5 9.5 4.9 7.3 1.1 1 0 0 1 1 1 0 Baculovirus protein of unknown function (DUF844) Bud13 PF09736.4 CDI74720.1 - 7.8 6.7 17.6 11 6.2 12.2 1.2 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex Cas1_AcylT PF07779.7 CDI74720.1 - 9 4.6 5.9 11 4.3 4.1 1.1 1 0 0 1 1 1 0 10 TM Acyl Transferase domain found in Cas1p DUF3260 PF11658.3 CDI74720.1 - 9.3 4.2 10.9 11 4.0 7.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3260) VIT1 PF01988.14 CDI74720.1 - 9.9 5.5 6.5 16 4.8 4.5 1.3 1 0 0 1 1 1 0 VIT family V-ATPase_H_N PF03224.9 CDI74722.1 - 0.00054 19.1 0.3 0.005 15.9 0.0 2.0 2 0 0 2 2 2 2 V-ATPase subunit H SR-25 PF10500.4 CDI74723.1 - 1.3 8.4 38.6 0.14 11.6 16.6 2.0 1 1 1 2 2 2 0 Nuclear RNA-splicing-associated protein DSPc PF00782.15 CDI74726.1 - 0.0015 18.1 0.0 0.0015 18.1 0.0 2.5 3 0 0 3 3 3 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 CDI74726.1 - 0.0018 18.5 1.2 0.0018 18.5 0.8 3.8 2 2 1 3 3 3 1 Tyrosine phosphatase family PolC_DP2 PF03833.8 CDI74726.1 - 8.8 3.8 10.7 13 3.2 7.0 1.5 2 0 0 2 2 2 0 DNA polymerase II large subunit DP2 PAT1 PF09770.4 CDI74727.1 - 0.0017 16.7 33.9 0.0017 16.7 23.5 6.8 3 2 1 5 5 5 3 Topoisomerase II-associated protein PAT1 CAF-1_p150 PF11600.3 CDI74728.1 - 1.4 8.2 66.0 2.3 7.5 0.1 3.1 3 0 0 3 3 3 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal OmpH PF03938.9 CDI74729.1 - 1.2 9.0 32.7 1.2 9.0 14.8 2.2 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Mitofilin PF09731.4 CDI74729.1 - 1.3 7.5 25.3 1.7 7.2 17.6 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Macoilin PF09726.4 CDI74729.1 - 1.4 7.1 37.4 1.8 6.7 25.9 1.1 1 0 0 1 1 1 0 Transmembrane protein Utp14 PF04615.8 CDI74729.1 - 1.4 6.9 20.5 1.9 6.5 14.2 1.2 1 0 0 1 1 1 0 Utp14 protein Med15 PF09606.5 CDI74731.1 - 1.2 7.2 95.5 1.7 6.7 66.2 1.3 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DivIC PF04977.10 CDI74732.1 - 0.0009 18.6 1.3 0.0009 18.6 0.9 2.6 2 0 0 2 2 2 1 Septum formation initiator OPA3 PF07047.7 CDI74732.1 - 0.0023 17.7 1.1 0.0023 17.7 0.8 2.3 2 0 0 2 2 2 1 Optic atrophy 3 protein (OPA3) ADIP PF11559.3 CDI74732.1 - 0.02 14.8 3.0 0.02 14.8 2.1 2.1 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding DUF1183 PF06682.7 CDI74732.1 - 0.051 13.1 0.0 0.051 13.1 0.0 2.1 2 1 0 2 2 1 0 Protein of unknown function (DUF1183) Tankyrase_bdg_C PF15327.1 CDI74732.1 - 0.12 12.5 7.2 0.16 12.1 5.0 1.0 1 0 0 1 1 1 0 Tankyrase binding protein C terminal domain Mycobact_memb PF05423.8 CDI74732.1 - 0.21 11.3 0.1 0.21 11.3 0.1 3.1 2 1 0 2 2 1 0 Mycobacterium membrane protein Rtf2 PF04641.7 CDI74732.1 - 0.31 10.2 8.3 0.37 9.9 5.8 1.0 1 0 0 1 1 1 0 Rtf2 RING-finger DUF3573 PF12097.3 CDI74732.1 - 0.36 9.3 5.0 0.61 8.6 3.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) Striatin PF08232.7 CDI74732.1 - 0.77 10.0 13.8 1 9.6 9.5 1.1 1 0 0 1 1 1 0 Striatin family APC8 PF04049.8 CDI74732.1 - 1.1 9.0 6.9 1.5 8.5 4.8 1.2 1 0 0 1 1 1 0 Anaphase promoting complex subunit 8 / Cdc23 OmpH PF03938.9 CDI74732.1 - 1.1 9.1 15.6 1.7 8.5 10.8 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF3373 PF11853.3 CDI74732.1 - 4.5 5.6 13.2 7.9 4.8 9.2 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3373) LMBR1 PF04791.11 CDI74732.1 - 6 5.3 23.0 9.3 4.7 16.0 1.4 1 1 0 1 1 1 0 LMBR1-like membrane protein Atg14 PF10186.4 CDI74732.1 - 8.5 5.2 15.7 13 4.6 10.9 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF2072 PF09845.4 CDI74734.1 - 0.11 12.4 0.1 0.21 11.4 0.1 1.5 1 0 0 1 1 1 0 Zn-ribbon containing protein (DUF2072) DBC1 PF14443.1 CDI74734.1 - 1.2 8.6 5.6 0.099 12.1 0.5 1.7 2 0 0 2 2 2 0 DBC1 gpUL132 PF11359.3 CDI74734.1 - 8.4 5.6 9.8 0.84 8.9 3.4 1.7 2 0 0 2 2 2 0 Glycoprotein UL132 Spt20 PF12090.3 CDI74735.1 - 5.6 6.2 8.6 7.7 5.8 6.0 1.2 1 0 0 1 1 1 0 Spt20 family PHD_3 PF13922.1 CDI74735.1 - 9.9 6.4 9.9 29 4.9 6.8 1.8 1 0 0 1 1 1 0 PHD domain of transcriptional enhancer, Asx PH_4 PF15404.1 CDI74736.1 - 0.0085 15.6 7.2 0.0084 15.6 5.0 1.2 1 0 0 1 1 1 1 Pleckstrin homology domain Cwf_Cwc_15 PF04889.7 CDI74736.1 - 0.0098 15.6 7.4 0.011 15.4 5.2 1.1 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein DUF775 PF05603.7 CDI74736.1 - 0.014 14.9 9.3 0.015 14.8 6.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF775) CAF-1_p150 PF11600.3 CDI74736.1 - 0.025 13.9 22.8 0.029 13.7 15.8 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal RAB3GAP2_N PF14655.1 CDI74736.1 - 0.027 13.4 11.1 0.041 12.8 7.7 1.3 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus SprA-related PF12118.3 CDI74736.1 - 0.032 13.5 22.2 0.038 13.3 15.4 1.2 1 0 0 1 1 1 0 SprA-related family Transposase_21 PF02992.9 CDI74736.1 - 0.046 12.8 4.4 0.055 12.5 3.0 1.0 1 0 0 1 1 1 0 Transposase family tnp2 PBP_sp32 PF07222.7 CDI74736.1 - 0.069 12.3 12.7 0.079 12.1 8.8 1.2 1 0 0 1 1 1 0 Proacrosin binding protein sp32 GNT-I PF03071.10 CDI74736.1 - 0.077 11.5 4.4 0.083 11.4 3.0 1.0 1 0 0 1 1 1 0 GNT-I family PRKCSH-like PF12999.2 CDI74736.1 - 0.13 11.8 8.8 0.16 11.5 6.1 1.1 1 0 0 1 1 1 0 Glucosidase II beta subunit-like RR_TM4-6 PF06459.7 CDI74736.1 - 0.24 11.2 9.5 0.24 11.2 6.6 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Corona_nucleoca PF00937.13 CDI74736.1 - 0.53 9.1 21.5 0.61 8.9 14.9 1.0 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein Suf PF05843.9 CDI74736.1 - 0.7 9.5 16.3 0.72 9.5 11.3 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DDHD PF02862.12 CDI74736.1 - 0.95 9.2 14.5 0.99 9.1 10.1 1.1 1 0 0 1 1 1 0 DDHD domain Gag_spuma PF03276.9 CDI74736.1 - 1.1 7.5 14.4 0.99 7.6 10.0 1.1 1 0 0 1 1 1 0 Spumavirus gag protein DUF4407 PF14362.1 CDI74736.1 - 1.3 7.9 9.0 1.3 7.8 6.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Macoilin PF09726.4 CDI74736.1 - 1.4 7.0 15.7 1.7 6.8 10.9 1.2 1 0 0 1 1 1 0 Transmembrane protein SSP160 PF06933.6 CDI74736.1 - 1.7 6.5 14.7 2 6.3 10.2 1.0 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DUF4557 PF15101.1 CDI74736.1 - 1.7 8.3 14.4 2 8.2 10.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) Dicty_REP PF05086.7 CDI74736.1 - 2.1 5.9 13.9 2.2 5.9 9.6 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein CagX PF03524.10 CDI74736.1 - 2.3 7.4 8.7 2.8 7.1 6.0 1.2 1 0 0 1 1 1 0 Conjugal transfer protein CDK2AP PF09806.4 CDI74736.1 - 2.5 8.2 17.6 3.7 7.7 12.2 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein CDK5_activator PF03261.10 CDI74736.1 - 2.5 7.3 17.1 2.9 7.1 11.9 1.0 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein FLO_LFY PF01698.11 CDI74736.1 - 2.6 6.8 11.5 2.8 6.6 8.0 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein DUF3474 PF11960.3 CDI74736.1 - 3.5 7.6 6.6 4.2 7.4 4.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3474) Band_3_cyto PF07565.8 CDI74736.1 - 4.9 6.5 11.4 5.3 6.4 7.9 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain RAP1 PF07218.6 CDI74736.1 - 5.4 4.9 8.2 5.2 5.0 5.7 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Herpes_DNAp_acc PF04929.7 CDI74736.1 - 5.5 5.8 15.4 5.8 5.7 10.7 1.0 1 0 0 1 1 1 0 Herpes DNA replication accessory factor DUF4446 PF14584.1 CDI74736.1 - 5.6 6.7 7.4 7.1 6.4 5.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) DUF3408 PF11888.3 CDI74736.1 - 6.1 6.7 11.7 7.2 6.5 8.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) DUF4228 PF14009.1 CDI74736.1 - 6.3 6.8 14.0 7.8 6.5 9.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4228) AUX_IAA PF02309.11 CDI74736.1 - 7 6.3 12.3 8 6.1 8.5 1.1 1 0 0 1 1 1 0 AUX/IAA family Coiled-coil_56 PF09813.4 CDI74736.1 - 8.4 6.4 10.6 12 5.9 7.3 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 56 DUF3801 PF12687.2 CDI74736.1 - 9.3 5.7 17.9 11 5.5 12.3 1.2 1 1 0 1 1 1 0 Protein of unknown function (DUF3801) SPX PF03105.14 CDI74737.1 - 0.0097 15.7 9.0 0.0092 15.7 6.3 1.2 1 0 0 1 1 1 1 SPX domain SAPS PF04499.10 CDI74737.1 - 0.014 14.0 10.7 0.012 14.3 7.4 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Spore_coat_CotO PF14153.1 CDI74737.1 - 0.074 12.4 24.4 0.082 12.3 16.9 1.1 1 0 0 1 1 1 0 Spore coat protein CotO Hid1 PF12722.2 CDI74737.1 - 0.13 9.8 17.1 0.12 10.0 11.9 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Peptidase_S64 PF08192.6 CDI74737.1 - 0.15 10.3 10.3 0.13 10.5 7.1 1.2 1 0 0 1 1 1 0 Peptidase family S64 TFIIF_alpha PF05793.7 CDI74737.1 - 0.17 10.2 14.6 0.19 10.0 10.1 1.0 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Macoilin PF09726.4 CDI74737.1 - 0.28 9.3 13.4 0.27 9.4 9.3 1.1 1 0 0 1 1 1 0 Transmembrane protein CDC45 PF02724.9 CDI74737.1 - 0.42 8.5 17.5 0.47 8.4 12.1 1.0 1 0 0 1 1 1 0 CDC45-like protein Band_3_cyto PF07565.8 CDI74737.1 - 0.51 9.8 14.7 0.63 9.5 10.2 1.3 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Herpes_BLLF1 PF05109.8 CDI74737.1 - 0.52 8.1 29.7 0.6 8.0 20.6 1.2 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) HlyD_2 PF12700.2 CDI74737.1 - 0.58 9.2 11.5 0.57 9.2 8.0 1.1 1 0 0 1 1 1 0 HlyD family secretion protein Otopetrin PF03189.8 CDI74737.1 - 0.79 8.6 6.5 0.69 8.8 4.5 1.1 1 0 0 1 1 1 0 Otopetrin LMBR1 PF04791.11 CDI74737.1 - 0.88 8.0 3.9 0.74 8.3 2.7 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein SMN PF06003.7 CDI74737.1 - 1.1 8.2 13.4 1.4 7.9 9.3 1.2 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) Plasmodium_Vir PF05795.6 CDI74737.1 - 1.4 8.0 6.1 1.6 7.8 4.2 1.4 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Cellulose_synt PF03552.9 CDI74737.1 - 1.7 6.8 5.3 1.8 6.7 3.7 1.0 1 0 0 1 1 1 0 Cellulose synthase DUF572 PF04502.8 CDI74737.1 - 2.5 7.2 21.0 2.8 7.0 14.6 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) Ycf1 PF05758.7 CDI74737.1 - 6 4.4 20.1 6.5 4.3 13.9 1.0 1 0 0 1 1 1 0 Ycf1 YjgP_YjgQ PF03739.9 CDI74737.1 - 7.2 5.2 5.7 7.4 5.2 3.9 1.1 1 0 0 1 1 1 0 Predicted permease YjgP/YjgQ family CAF-1_p150 PF11600.3 CDI74740.1 - 0.00069 19.0 20.5 0.00069 19.0 14.2 11.2 9 2 2 11 11 11 4 Chromatin assembly factor 1 complex p150 subunit, N-terminal TRAPPC9-Trs120 PF08626.6 CDI74742.1 - 1.5e-10 39.1 0.0 1.5e-10 39.1 0.0 3.1 3 1 1 4 4 4 1 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit Sdh5 PF03937.11 CDI74744.1 - 0.11 12.1 1.4 0.17 11.5 1.0 1.3 1 0 0 1 1 1 0 Flavinator of succinate dehydrogenase Cnd2 PF05786.9 CDI74745.1 - 0.0013 17.3 13.0 0.0016 17.0 9.0 1.2 1 0 0 1 1 1 1 Condensin complex subunit 2 Ribosomal_60s PF00428.14 CDI74745.1 - 0.0039 17.5 23.1 0.014 15.7 4.5 2.5 2 1 1 3 3 2 2 60s Acidic ribosomal protein DUF4175 PF13779.1 CDI74745.1 - 0.0086 13.8 41.4 0.0089 13.7 28.7 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4175) DUF4557 PF15101.1 CDI74745.1 - 0.013 15.3 24.2 0.017 14.9 16.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) Tir_receptor_N PF07490.6 CDI74745.1 - 0.026 14.1 0.8 0.036 13.6 0.6 1.3 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) N-terminus Med15 PF09606.5 CDI74745.1 - 0.059 11.5 57.4 0.065 11.4 39.8 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal SAGA-Tad1 PF12767.2 CDI74745.1 - 0.092 12.3 18.4 0.1 12.2 12.7 1.1 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit DDHD PF02862.12 CDI74745.1 - 0.16 11.7 16.3 0.18 11.5 11.3 1.1 1 0 0 1 1 1 0 DDHD domain Bud13 PF09736.4 CDI74745.1 - 0.19 11.9 22.5 0.27 11.5 15.6 1.4 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex AUX_IAA PF02309.11 CDI74745.1 - 0.2 11.3 13.6 0.23 11.1 9.4 1.2 1 0 0 1 1 1 0 AUX/IAA family FAM60A PF15396.1 CDI74745.1 - 0.34 10.6 15.5 0.44 10.2 10.8 1.1 1 0 0 1 1 1 0 Protein Family FAM60A RR_TM4-6 PF06459.7 CDI74745.1 - 0.36 10.6 18.7 0.48 10.2 13.0 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Hid1 PF12722.2 CDI74745.1 - 0.44 8.1 17.9 0.42 8.2 12.4 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein YjgP_YjgQ PF03739.9 CDI74745.1 - 0.51 9.0 8.0 0.55 8.9 5.6 1.1 1 0 0 1 1 1 0 Predicted permease YjgP/YjgQ family RNA_pol_Rpb1_5 PF04998.12 CDI74745.1 - 0.57 9.3 12.4 0.73 9.0 8.6 1.1 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 CDC45 PF02724.9 CDI74745.1 - 0.57 8.1 16.4 0.54 8.2 11.4 1.0 1 0 0 1 1 1 0 CDC45-like protein LicD PF04991.8 CDI74745.1 - 0.59 10.2 4.2 0.74 9.8 2.9 1.1 1 0 0 1 1 1 0 LicD family PIH1 PF08190.7 CDI74745.1 - 0.59 9.5 20.6 0.63 9.4 14.3 1.1 1 0 0 1 1 1 0 pre-RNA processing PIH1/Nop17 Spore_coat_CotO PF14153.1 CDI74745.1 - 0.7 9.2 26.2 0.83 9.0 18.1 1.2 1 0 0 1 1 1 0 Spore coat protein CotO Raftlin PF15250.1 CDI74745.1 - 0.73 8.2 18.0 0.86 8.0 12.5 1.1 1 0 0 1 1 1 0 Raftlin PAT1 PF09770.4 CDI74745.1 - 0.89 7.7 42.3 0.86 7.7 29.4 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Ycf1 PF05758.7 CDI74745.1 - 0.93 7.1 20.5 1 6.9 14.2 1.0 1 0 0 1 1 1 0 Ycf1 Shadoo PF14999.1 CDI74745.1 - 0.94 9.3 11.3 1.1 9.1 0.1 2.1 2 0 0 2 2 2 0 Shadow of prion protein, neuroprotective Band_3_cyto PF07565.8 CDI74745.1 - 0.99 8.8 18.4 1.3 8.5 12.8 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Cellulose_synt PF03552.9 CDI74745.1 - 1.1 7.4 8.4 1.2 7.3 5.9 1.0 1 0 0 1 1 1 0 Cellulose synthase DUF4045 PF13254.1 CDI74745.1 - 1.2 8.3 20.3 1.3 8.2 14.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) eIF-3_zeta PF05091.7 CDI74745.1 - 1.3 7.5 23.8 1.4 7.4 16.5 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Sec62 PF03839.11 CDI74745.1 - 1.4 8.3 15.6 1.7 8.0 10.8 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 HGTP_anticodon2 PF12745.2 CDI74745.1 - 1.4 7.9 16.5 1.7 7.7 11.4 1.1 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs Dsh_C PF12316.3 CDI74745.1 - 1.6 8.7 11.6 1.8 8.6 8.0 1.1 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal DUF4638 PF15472.1 CDI74745.1 - 1.8 8.0 13.8 2.1 7.9 9.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) Mem_trans PF03547.13 CDI74745.1 - 1.9 6.6 6.8 2 6.6 4.7 1.1 1 0 0 1 1 1 0 Membrane transport protein Glyco_transf_6 PF03414.8 CDI74745.1 - 2 6.8 10.5 2.2 6.6 7.3 1.1 1 0 0 1 1 1 0 Glycosyltransferase family 6 BTV_NS2 PF04514.7 CDI74745.1 - 2.1 7.1 15.9 2.4 6.9 11.0 1.0 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 DUF913 PF06025.7 CDI74745.1 - 2.2 6.9 13.1 2.6 6.6 9.1 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Herpes_env PF01673.13 CDI74745.1 - 2.4 6.6 15.9 2.7 6.4 11.0 1.0 1 0 0 1 1 1 0 Herpesvirus putative major envelope glycoprotein Plasmodium_Vir PF05795.6 CDI74745.1 - 2.7 7.1 8.4 3 6.9 5.8 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Gag_spuma PF03276.9 CDI74745.1 - 2.8 6.1 32.9 3.3 5.9 22.8 1.2 1 0 0 1 1 1 0 Spumavirus gag protein Hom_end_hint PF05203.11 CDI74745.1 - 2.9 7.5 12.5 3.9 7.1 8.7 1.3 1 0 0 1 1 1 0 Hom_end-associated Hint Mgr1 PF08602.5 CDI74745.1 - 2.9 6.8 8.5 3.2 6.6 5.9 1.2 1 0 0 1 1 1 0 Mgr1-like, i-AAA protease complex subunit F-protein PF00469.15 CDI74745.1 - 3.2 7.0 17.3 4.1 6.7 12.0 1.3 1 0 0 1 1 1 0 Negative factor, (F-Protein) or Nef Peptidase_U57 PF05582.7 CDI74745.1 - 3.5 6.5 12.5 4.8 6.0 8.7 1.4 1 0 0 1 1 1 0 YabG peptidase U57 Neur_chan_memb PF02932.11 CDI74745.1 - 3.8 7.3 14.2 3.7 7.3 9.8 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DHHW PF14286.1 CDI74745.1 - 3.9 6.7 14.4 4.1 6.6 10.0 1.1 1 0 0 1 1 1 0 DHHW protein GPCR_chapero_1 PF11904.3 CDI74745.1 - 4 6.4 16.8 5 6.1 11.7 1.2 1 0 0 1 1 1 0 GPCR-chaperone Glyco_transf_15 PF01793.11 CDI74745.1 - 4.1 6.2 14.1 5 5.9 9.8 1.3 1 0 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase FLO_LFY PF01698.11 CDI74745.1 - 4.1 6.1 19.3 5.1 5.8 13.4 1.2 1 0 0 1 1 1 0 Floricaula / Leafy protein Macoilin PF09726.4 CDI74745.1 - 4.2 5.5 21.5 4.7 5.3 14.9 1.1 1 0 0 1 1 1 0 Transmembrane protein YABBY PF04690.8 CDI74745.1 - 4.4 7.5 10.5 6.3 7.0 7.3 1.4 1 0 0 1 1 1 0 YABBY protein Asp-B-Hydro_N PF05279.6 CDI74745.1 - 4.5 7.0 19.5 4.7 6.9 13.5 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region DUF1675 PF07897.6 CDI74745.1 - 4.8 6.9 13.6 6 6.6 9.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) Paramyxo_ncap PF00973.14 CDI74745.1 - 5.3 5.6 16.3 5.5 5.5 11.3 1.0 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Zip PF02535.17 CDI74745.1 - 5.3 5.9 10.1 6.2 5.7 7.0 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter NMDAR2_C PF10565.4 CDI74745.1 - 5.6 5.4 20.4 6.4 5.3 14.1 1.3 1 0 0 1 1 1 0 N-methyl D-aspartate receptor 2B3 C-terminus TFIIA PF03153.8 CDI74745.1 - 6.5 6.5 34.9 8.5 6.1 24.2 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Serinc PF03348.10 CDI74745.1 - 7.8 5.0 16.1 10 4.6 11.2 1.3 1 0 0 1 1 1 0 Serine incorporator (Serinc) Folate_carrier PF01770.13 CDI74745.1 - 8.1 4.8 10.6 9.3 4.6 7.4 1.2 1 0 0 1 1 1 0 Reduced folate carrier Conotoxin PF02950.12 CDI74747.1 - 0.023 15.4 1.1 0.023 15.4 0.8 4.3 4 0 0 4 4 4 0 Conotoxin EphA2_TM PF14575.1 CDI74747.1 - 3.2 8.2 4.5 14 6.1 0.0 3.3 3 0 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain NAM PF02365.10 CDI74748.1 - 0.34 11.0 7.7 0.36 11.0 5.3 1.1 1 0 0 1 1 1 0 No apical meristem (NAM) protein SelP_N PF04592.9 CDI74748.1 - 0.54 9.5 28.4 0.63 9.3 19.7 1.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Spore_YhcN_YlaJ PF09580.5 CDI74748.1 - 0.74 9.8 28.4 0.98 9.5 19.7 1.1 1 0 0 1 1 1 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) DUF688 PF05097.7 CDI74748.1 - 1.7 7.5 19.3 1.8 7.4 13.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF688) FAM60A PF15396.1 CDI74748.1 - 2.7 7.7 17.7 2.9 7.5 12.3 1.1 1 0 0 1 1 1 0 Protein Family FAM60A Macoilin PF09726.4 CDI74748.1 - 6.7 4.8 22.3 7.8 4.6 15.4 1.1 1 0 0 1 1 1 0 Transmembrane protein DUF1510 PF07423.6 CDI74748.1 - 7 5.9 25.8 8.2 5.7 17.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Zip PF02535.17 CDI74748.1 - 7.4 5.4 24.0 8.4 5.2 16.6 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Utp14 PF04615.8 CDI74748.1 - 8.3 4.4 27.1 9.3 4.2 18.8 1.0 1 0 0 1 1 1 0 Utp14 protein DDRGK PF09756.4 CDI74748.1 - 8.8 5.6 30.2 11 5.3 20.9 1.1 1 0 0 1 1 1 0 DDRGK domain F-protein PF00469.15 CDI74748.1 - 8.9 5.6 20.2 9.5 5.5 14.0 1.0 1 0 0 1 1 1 0 Negative factor, (F-Protein) or Nef PAT1 PF09770.4 CDI74749.1 - 3.4e-07 28.9 96.8 4.9e-07 28.4 67.1 1.3 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 LsmAD PF06741.8 CDI74750.1 - 0.00074 19.5 3.5 0.00074 19.5 2.4 5.8 5 1 1 6 6 6 1 LsmAD domain DUF755 PF05501.6 CDI74750.1 - 0.0099 15.9 27.5 0.0099 15.9 19.1 11.8 6 2 4 10 10 10 1 Domain of unknown function (DUF755) DUF4259 PF14078.1 CDI74750.1 - 0.018 15.5 4.0 0.018 15.5 2.8 6.6 6 1 0 6 6 6 0 Domain of unknown function (DUF4259) Pkinase PF00069.20 CDI74752.1 - 1.4e-17 63.7 0.0 3.3e-14 52.6 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CDI74752.1 - 1.3e-10 40.8 0.0 1.6e-10 40.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CDI74752.1 - 8.3e-05 21.6 0.0 0.00013 21.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Chromo PF00385.19 CDI74753.1 - 1.1e-07 31.3 0.0 1.9e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain MSA-2c PF12238.3 CDI74753.1 - 0.2 11.3 2.2 0.25 10.9 1.5 1.1 1 0 0 1 1 1 0 Merozoite surface antigen 2c LCAT PF02450.10 CDI74754.1 - 3.8e-21 75.5 0.0 4.3e-15 55.5 0.0 2.3 2 0 0 2 2 2 2 Lecithin:cholesterol acyltransferase Aminoglyc_resit PF10706.4 CDI74754.1 - 0.086 12.4 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 Aminoglycoside-2''-adenylyltransferase zf-RING_5 PF14634.1 CDI74755.1 - 9e-05 22.1 7.9 0.00028 20.5 5.5 1.9 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 CDI74755.1 - 0.00027 20.7 13.4 0.00075 19.2 8.5 2.4 1 1 0 1 1 1 1 Ring finger domain Prok-RING_1 PF14446.1 CDI74755.1 - 0.0086 15.7 9.4 0.026 14.2 6.5 1.8 1 1 0 1 1 1 1 Prokaryotic RING finger family 1 zf-C3HC4_2 PF13923.1 CDI74755.1 - 0.018 15.0 11.5 0.018 15.0 7.9 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CDI74755.1 - 0.024 14.2 6.9 0.081 12.6 4.8 2.0 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) MscS_porin PF12795.2 CDI74755.1 - 0.063 12.5 5.9 0.086 12.1 3.5 1.5 1 1 0 1 1 1 0 Mechanosensitive ion channel porin domain zf-C3HC4_3 PF13920.1 CDI74755.1 - 0.083 12.5 14.1 0.041 13.5 7.8 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) PhoU PF01895.14 CDI74755.1 - 0.12 12.8 1.8 0.18 12.2 0.9 1.5 1 1 0 1 1 1 0 PhoU domain YPEB PF14620.1 CDI74755.1 - 0.16 10.9 1.6 0.25 10.3 0.1 1.8 1 1 1 2 2 2 0 YpeB sporulation IFP_35_N PF07334.8 CDI74755.1 - 0.91 9.5 4.1 2.9 7.9 0.7 2.9 2 1 0 2 2 2 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus DUF4206 PF13901.1 CDI74755.1 - 1.5 8.3 6.8 1.7 8.1 1.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4206) Med15 PF09606.5 CDI74757.1 - 9 4.3 112.1 0.11 10.7 16.7 2.1 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal Dehydrin PF00257.14 CDI74758.1 - 0.00042 20.6 0.1 0.00042 20.6 0.0 7.7 3 3 0 4 4 4 1 Dehydrin WhiA_N PF10298.4 CDI74758.1 - 0.0035 17.1 1.3 0.0096 15.7 0.9 1.7 1 0 0 1 1 1 1 WhiA N-terminal LAGLIDADG-like domain SseC PF04888.7 CDI74758.1 - 0.0035 16.7 14.3 0.0035 16.7 9.9 8.4 5 2 1 6 6 6 1 Secretion system effector C (SseC) like family Herpes_DNAp_acc PF04929.7 CDI74758.1 - 0.0055 15.7 2.0 0.0055 15.7 1.4 5.2 2 2 1 4 4 4 1 Herpes DNA replication accessory factor AAA_23 PF13476.1 CDI74758.1 - 0.0099 16.2 2.3 0.0099 16.2 1.6 5.5 2 1 1 3 3 3 1 AAA domain DUF1510 PF07423.6 CDI74759.1 - 0.0018 17.6 5.2 0.0018 17.6 3.6 3.2 2 1 1 3 3 3 1 Protein of unknown function (DUF1510) DUF2077 PF09850.4 CDI74759.1 - 0.0057 16.0 1.1 0.0057 16.0 0.8 5.6 4 1 0 6 6 6 1 Uncharacterized protein conserved in bacteria (DUF2077) SKN1 PF03935.10 CDI74759.1 - 0.1 10.7 3.2 0.18 9.9 2.2 1.4 1 0 0 1 1 1 0 Beta-glucan synthesis-associated protein (SKN1) DUF2207 PF09972.4 CDI74759.1 - 8.2 4.8 7.8 0.71 8.3 1.4 1.8 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) Pkinase PF00069.20 CDI74760.1 - 8.8e-29 100.4 4.5 1.5e-27 96.3 3.1 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDI74760.1 - 3.5e-10 39.4 1.3 4.2e-07 29.3 0.1 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.18 CDI74760.1 - 0.00017 21.4 18.6 0.00024 20.9 12.9 1.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family PAT1 PF09770.4 CDI74760.1 - 0.0011 17.2 28.5 0.0014 16.9 19.8 1.1 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 Choline_kinase PF01633.15 CDI74760.1 - 0.01 15.4 2.1 0.01 15.4 1.4 1.8 1 1 0 2 2 2 0 Choline/ethanolamine kinase Kdo PF06293.9 CDI74760.1 - 0.01 14.8 1.3 0.019 14.0 0.6 1.6 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 CDI74760.1 - 0.021 14.2 0.3 0.021 14.2 0.2 1.7 2 1 0 2 2 1 0 RIO1 family RskA PF10099.4 CDI74760.1 - 0.028 14.1 13.6 0.046 13.4 9.4 1.3 1 0 0 1 1 1 0 Anti-sigma-K factor rskA SAGA-Tad1 PF12767.2 CDI74760.1 - 0.029 14.0 7.2 0.042 13.5 5.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit TFIIA PF03153.8 CDI74760.1 - 0.039 13.8 22.0 0.05 13.4 15.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DDHD PF02862.12 CDI74760.1 - 0.049 13.4 3.3 0.069 12.9 2.3 1.2 1 0 0 1 1 1 0 DDHD domain XAP5 PF04921.9 CDI74760.1 - 0.097 12.2 2.6 0.13 11.8 1.8 1.2 1 0 0 1 1 1 0 XAP5, circadian clock regulator Neur_chan_memb PF02932.11 CDI74760.1 - 0.15 11.9 4.0 0.17 11.7 2.8 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region YrbL-PhoP_reg PF10707.4 CDI74760.1 - 0.16 11.2 0.0 0.16 11.2 0.0 2.3 2 1 1 3 3 3 0 PhoP regulatory network protein YrbL Bul1_C PF04426.7 CDI74760.1 - 0.2 10.8 3.6 0.28 10.3 2.5 1.1 1 0 0 1 1 1 0 Bul1 C terminus Herpes_UL87 PF03043.9 CDI74760.1 - 0.34 9.2 3.1 0.39 9.0 2.2 1.1 1 0 0 1 1 1 0 Herpesvirus UL87 family DUF4647 PF15504.1 CDI74760.1 - 0.46 9.3 13.0 0.59 8.9 9.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4647) NPR3 PF03666.8 CDI74760.1 - 0.51 8.8 8.0 0.7 8.3 5.6 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Ndc1_Nup PF09531.5 CDI74760.1 - 0.55 8.5 8.5 0.66 8.3 5.9 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup FAM60A PF15396.1 CDI74760.1 - 0.64 9.7 7.1 0.91 9.2 4.9 1.2 1 0 0 1 1 1 0 Protein Family FAM60A BAT2_N PF07001.6 CDI74760.1 - 1.1 9.5 22.4 1.5 9.1 15.5 1.1 1 0 0 1 1 1 0 BAT2 N-terminus Mif2_N PF15624.1 CDI74760.1 - 1.1 9.8 6.8 1.6 9.3 4.7 1.2 1 0 0 1 1 1 0 Kinetochore CENP-C fungal homologue, Mif2, N-terminal DivIC PF04977.10 CDI74760.1 - 1.5 8.3 18.5 1.8 8.1 4.0 2.3 2 0 0 2 2 2 0 Septum formation initiator Nucleo_P87 PF07267.6 CDI74760.1 - 2 6.9 10.4 2.6 6.6 7.2 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 DUF2201_N PF13203.1 CDI74760.1 - 2.1 7.4 16.2 2.9 7.0 11.2 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain Rtf2 PF04641.7 CDI74760.1 - 2.1 7.4 10.1 2.9 7.0 7.0 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger Lin-8 PF03353.10 CDI74760.1 - 2.3 7.4 12.0 3.8 6.7 8.3 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Hid1 PF12722.2 CDI74760.1 - 2.4 5.7 9.2 2.9 5.4 6.4 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein EphA2_TM PF14575.1 CDI74760.1 - 3.5 8.0 5.5 25 5.3 0.1 2.4 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Presenilin PF01080.12 CDI74760.1 - 5.1 5.8 7.6 6.7 5.4 5.3 1.1 1 0 0 1 1 1 0 Presenilin DUF1180 PF06679.7 CDI74760.1 - 8.6 6.2 7.7 12 5.7 5.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) DUF666 PF05006.7 CDI74761.1 - 0.011 15.7 0.6 0.018 15.0 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF666) DUF1183 PF06682.7 CDI74761.1 - 4.3 6.8 15.3 5.3 6.5 10.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) DUF3357 PF11837.3 CDI74762.1 - 0.051 13.4 2.7 4.8 7.0 0.2 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF3357) Mucin PF01456.12 CDI74762.1 - 0.22 11.2 16.1 0.026 14.3 4.2 2.2 1 1 1 2 2 2 0 Mucin-like glycoprotein SpoIIIAH PF12685.2 CDI74764.1 - 0.091 12.2 10.0 0.11 11.9 6.9 1.0 1 0 0 1 1 1 0 SpoIIIAH-like protein AAA_13 PF13166.1 CDI74764.1 - 0.4 9.0 3.7 0.41 9.0 2.6 1.0 1 0 0 1 1 1 0 AAA domain Cytochrome-c551 PF10643.4 CDI74764.1 - 0.62 9.3 7.9 0.68 9.1 5.5 1.1 1 0 0 1 1 1 0 Photosystem P840 reaction-centre cytochrome c-551 DUF3138 PF11336.3 CDI74764.1 - 1.5 6.8 15.6 1.7 6.7 10.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) TraV PF09676.5 CDI74764.1 - 2.4 8.8 10.1 3 8.5 7.0 1.1 1 0 0 1 1 1 0 Type IV conjugative transfer system lipoprotein (TraV) AIF-MLS PF14962.1 CDI74764.1 - 7.9 6.0 22.7 9.5 5.8 15.7 1.1 1 0 0 1 1 1 0 Mitochondria Localisation Sequence IncA PF04156.9 CDI74766.1 - 0.00012 21.7 16.7 0.00012 21.7 11.6 5.2 3 1 2 5 5 2 1 IncA protein DUF1510 PF07423.6 CDI74766.1 - 0.00016 21.1 0.7 0.00016 21.1 0.5 4.8 4 1 1 5 5 4 1 Protein of unknown function (DUF1510) DUF4131 PF13567.1 CDI74766.1 - 0.00022 20.6 3.8 0.00022 20.6 2.6 3.7 3 1 0 3 3 1 1 Domain of unknown function (DUF4131) FA_desaturase PF00487.19 CDI74766.1 - 0.0003 20.3 0.1 0.00067 19.1 0.1 1.5 1 0 0 1 1 1 1 Fatty acid desaturase FimP PF09766.4 CDI74766.1 - 0.00048 19.3 7.5 0.00048 19.3 5.2 5.1 3 1 2 5 5 3 2 Fms-interacting protein YfhO PF09586.5 CDI74766.1 - 0.00083 17.5 6.0 0.00083 17.5 4.1 3.3 3 0 0 3 3 2 1 Bacterial membrane protein YfhO SpoIIIAH PF12685.2 CDI74766.1 - 0.0049 16.3 0.2 0.0049 16.3 0.2 5.5 3 1 1 4 4 2 2 SpoIIIAH-like protein LMBR1 PF04791.11 CDI74766.1 - 0.01 14.4 0.0 0.01 14.4 0.0 3.5 2 2 2 4 4 3 0 LMBR1-like membrane protein Pex24p PF06398.6 CDI74766.1 - 0.021 13.6 0.4 0.021 13.6 0.3 3.0 3 1 1 4 4 3 0 Integral peroxisomal membrane peroxin Shisa PF13908.1 CDI74766.1 - 0.028 14.5 1.0 0.028 14.5 0.7 6.0 4 1 1 5 5 4 0 Wnt and FGF inhibitory regulator Spore_YhcN_YlaJ PF09580.5 CDI74766.1 - 0.04 14.0 0.1 0.04 14.0 0.1 4.4 4 0 0 4 4 4 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) FAM176 PF14851.1 CDI74766.1 - 0.04 13.6 0.5 0.04 13.6 0.4 5.5 3 1 2 5 5 5 0 FAM176 family PRA1 PF03208.14 CDI74766.1 - 0.06 12.6 2.5 0.2 11.0 1.7 1.9 1 0 0 1 1 1 0 PRA1 family protein TRP PF06011.7 CDI74766.1 - 0.062 11.8 0.0 0.062 11.8 0.0 3.2 3 1 0 3 3 1 0 Transient receptor potential (TRP) ion channel Kei1 PF08552.6 CDI74766.1 - 0.082 12.5 0.2 0.082 12.5 0.1 6.9 3 1 0 3 3 2 0 Inositolphosphorylceramide synthase subunit Kei1 DUF4389 PF14333.1 CDI74766.1 - 0.71 9.6 5.0 1.2 8.8 3.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4389) Herpes_LMP1 PF05297.6 CDI74766.1 - 5.6 5.7 9.7 15 4.3 6.7 1.7 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) Pex14_N PF04695.8 CDI74768.1 - 0.015 15.3 1.2 0.026 14.5 0.8 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF2722 PF10846.3 CDI74768.1 - 0.035 13.1 4.6 0.45 9.4 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) DUF3735 PF12537.3 CDI74768.1 - 0.33 11.0 2.3 14 5.7 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3735) PHD_3 PF13922.1 CDI74768.1 - 5.5 7.3 7.4 0.2 11.9 0.8 2.0 2 0 0 2 2 2 0 PHD domain of transcriptional enhancer, Asx DUF3682 PF12446.3 CDI74769.1 - 0.0098 16.1 20.9 0.0098 16.1 14.5 15.0 8 6 3 11 11 11 2 Protein of unknown function (DUF3682) TPT PF03151.11 CDI74769.1 - 0.57 9.8 2.8 2.1 7.9 1.9 2.0 1 0 0 1 1 1 0 Triose-phosphate Transporter family PAT1 PF09770.4 CDI74770.1 - 0.011 14.0 64.7 0.011 14.0 44.9 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 HemX PF04375.9 CDI74770.1 - 0.35 9.3 41.7 0.72 8.3 28.9 1.5 1 1 0 1 1 1 0 HemX DUF1510 PF07423.6 CDI74770.1 - 0.92 8.8 31.8 1.1 8.6 22.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Pox_Ag35 PF03286.9 CDI74770.1 - 1.5 8.2 21.4 1.8 8.0 14.8 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Bac_luciferase PF00296.15 CDI74770.1 - 1.5 7.8 9.3 18 4.2 6.4 2.0 1 1 0 1 1 1 0 Luciferase-like monooxygenase DUF4045 PF13254.1 CDI74770.1 - 1.7 7.8 28.2 1.8 7.7 19.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) SAGA-Tad1 PF12767.2 CDI74770.1 - 3.2 7.3 33.9 3.6 7.1 23.5 1.1 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit RR_TM4-6 PF06459.7 CDI74770.1 - 3.8 7.3 29.4 5.5 6.8 20.4 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Asp-B-Hydro_N PF05279.6 CDI74770.1 - 4.1 7.1 24.2 4.1 7.1 16.8 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Med15 PF09606.5 CDI74770.1 - 4.4 5.3 93.7 4.9 5.2 64.9 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal CDC45 PF02724.9 CDI74770.1 - 5.2 4.9 32.2 5.9 4.8 22.3 1.0 1 0 0 1 1 1 0 CDC45-like protein PRP1_N PF06424.7 CDI74770.1 - 5.3 7.3 23.0 6.1 7.1 15.9 1.2 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal ABC2_membrane_2 PF12679.2 CDI74771.1 - 0.006 15.4 4.0 0.0077 15.1 2.7 1.2 1 0 0 1 1 1 1 ABC-2 family transporter protein Pex14_N PF04695.8 CDI74771.1 - 0.008 16.2 5.6 0.01 15.9 3.9 1.2 1 0 0 1 1 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region CbiQ PF02361.11 CDI74771.1 - 0.011 15.3 1.9 0.014 14.9 1.3 1.1 1 0 0 1 1 1 0 Cobalt transport protein FAM176 PF14851.1 CDI74771.1 - 0.046 13.4 0.3 0.065 12.9 0.2 1.3 1 0 0 1 1 1 0 FAM176 family MRI PF15325.1 CDI74771.1 - 0.071 14.0 0.5 0.11 13.5 0.3 1.2 1 0 0 1 1 1 0 Modulator of retrovirus infection DUF1510 PF07423.6 CDI74771.1 - 0.12 11.7 5.8 0.38 10.0 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) Ctr PF04145.10 CDI74771.1 - 0.12 12.3 1.8 0.18 11.8 1.1 1.4 1 1 0 1 1 1 0 Ctr copper transporter family APC_CDC26 PF10471.4 CDI74771.1 - 0.27 12.0 10.3 0.49 11.1 7.2 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex APC subunit 1 DUF1635 PF07795.6 CDI74771.1 - 0.89 8.8 9.8 1.2 8.5 6.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) CAF-1_p150 PF11600.3 CDI74771.1 - 1.6 8.0 7.6 2.3 7.5 5.3 1.3 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF1180 PF06679.7 CDI74771.1 - 2.4 7.9 7.7 4.3 7.1 5.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1180) DUF912 PF06024.7 CDI74771.1 - 2.5 8.2 15.1 0.21 11.6 2.9 2.2 1 1 1 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Arv1 PF04161.8 CDI74771.1 - 3.1 7.6 9.0 4.1 7.2 6.3 1.2 1 0 0 1 1 1 0 Arv1-like family Conotoxin PF02950.12 CDI74771.1 - 4.5 8.1 8.9 13 6.7 6.2 1.9 1 1 0 1 1 1 0 Conotoxin MIP-T3 PF10243.4 CDI74773.1 - 1.5 7.1 49.8 1.9 6.8 34.5 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Antistasin PF02822.9 CDI74773.1 - 3.6 7.9 7.2 5.8 7.3 5.0 1.3 1 0 0 1 1 1 0 Antistasin family Daxx PF03344.10 CDI74773.1 - 6 5.2 36.9 7.5 4.9 25.6 1.1 1 0 0 1 1 1 0 Daxx Family EMG1 PF03587.9 CDI74774.1 - 3e-43 147.4 0.1 1.6e-32 112.4 0.1 2.1 1 1 1 2 2 2 2 EMG1/NEP1 methyltransferase Radial_spoke_3 PF06098.6 CDI74775.1 - 4.4e-05 22.6 11.8 4.4e-05 22.6 8.2 2.2 2 0 0 2 2 2 1 Radial spoke protein 3 TRM13 PF05206.9 CDI74776.1 - 2.3e-16 59.8 2.7 4.5e-08 32.6 0.0 4.4 4 1 1 5 5 5 3 Methyltransferase TRM13 zf-U11-48K PF05253.7 CDI74776.1 - 0.028 14.1 0.2 0.059 13.1 0.1 1.6 1 0 0 1 1 1 0 U11-48K-like CHHC zinc finger BAF1_ABF1 PF04684.8 CDI74776.1 - 0.26 10.1 7.8 0.81 8.4 5.4 1.8 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Vac14_Fig4_bd PF11916.3 CDI74777.1 - 3.5e-36 124.0 4.0 1.2e-31 109.2 1.5 2.4 2 0 0 2 2 2 2 Vacuolar protein 14 C-terminal Fig4p binding Shikimate_dh_N PF08501.6 CDI74778.1 - 1.9e-07 30.9 0.1 6.1e-06 26.2 0.0 3.2 2 0 0 2 2 2 1 Shikimate dehydrogenase substrate binding domain EphA2_TM PF14575.1 CDI74779.1 - 0.0023 18.2 1.1 0.0023 18.2 0.8 7.0 5 1 0 5 5 5 1 Ephrin type-A receptor 2 transmembrane domain 60KD_IMP PF02096.15 CDI74779.1 - 0.0078 15.8 0.8 0.0078 15.8 0.6 6.2 3 1 1 4 4 4 1 60Kd inner membrane protein DUF3357 PF11837.3 CDI74779.1 - 0.015 15.1 0.2 0.015 15.1 0.1 6.1 5 2 2 7 7 7 0 Domain of unknown function (DUF3357) DUF165 PF02592.10 CDI74779.1 - 0.31 11.2 0.0 0.31 11.2 0.0 3.1 3 0 0 3 3 3 0 Uncharacterized ACR, YhhQ family COG1738 Syntaxin PF00804.20 CDI74781.1 - 0.0053 16.8 1.3 0.0068 16.5 0.9 1.1 1 0 0 1 1 1 1 Syntaxin IncA PF04156.9 CDI74781.1 - 0.1 12.1 4.9 0.12 11.9 3.4 1.1 1 0 0 1 1 1 0 IncA protein tRNA-synt_His PF13393.1 CDI74781.1 - 0.35 9.8 3.9 0.42 9.6 2.7 1.1 1 0 0 1 1 1 0 Histidyl-tRNA synthetase FUSC PF04632.7 CDI74781.1 - 0.46 8.8 9.6 0.54 8.6 6.6 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family HlyD PF00529.15 CDI74781.1 - 1.4 8.1 13.3 1.6 7.9 9.2 1.0 1 0 0 1 1 1 0 HlyD family secretion protein DUF4404 PF14357.1 CDI74781.1 - 2 8.8 9.3 2.8 8.4 6.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4404) DUF904 PF06005.7 CDI74781.1 - 7 7.0 8.9 1.2 9.5 3.7 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF904) UBA PF00627.26 CDI74782.1 - 3.8e-09 36.1 0.1 9.1e-09 34.9 0.1 1.7 1 0 0 1 1 1 1 UBA/TS-N domain Biotin_lipoyl PF00364.17 CDI74783.1 - 5.4e-12 45.1 0.0 9.3e-12 44.4 0.0 1.3 1 0 0 1 1 1 1 Biotin-requiring enzyme RskA PF10099.4 CDI74783.1 - 0.0065 16.2 8.1 0.0065 16.2 5.6 10.0 3 2 4 7 7 7 2 Anti-sigma-K factor rskA CagX PF03524.10 CDI74783.1 - 0.013 14.7 0.3 0.013 14.7 0.2 7.9 7 3 1 8 8 8 0 Conjugal transfer protein SprA-related PF12118.3 CDI74784.1 - 1.9e-05 24.1 46.9 2.3e-05 23.9 32.5 1.0 1 0 0 1 1 1 1 SprA-related family AAA_23 PF13476.1 CDI74784.1 - 0.069 13.4 16.7 0.088 13.1 11.6 1.2 1 0 0 1 1 1 0 AAA domain SR-25 PF10500.4 CDI74784.1 - 0.19 11.1 55.6 1.2 8.5 21.3 2.2 1 1 1 2 2 2 0 Nuclear RNA-splicing-associated protein DUF4355 PF14265.1 CDI74784.1 - 2 8.3 23.8 1.1 9.1 12.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4355) Med15 PF09606.5 CDI74784.1 - 5.2 5.1 64.9 6.4 4.8 45.0 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal PAT1 PF09770.4 CDI74784.1 - 7.2 4.7 52.9 8.9 4.4 36.6 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF1510 PF07423.6 CDI74785.1 - 0.36 10.1 32.6 0.41 9.9 22.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DUF3520 PF12034.3 CDI74785.1 - 0.45 10.6 17.6 0.69 10.0 12.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3520) DUF4400 PF14348.1 CDI74785.1 - 2.8 7.2 14.5 3.1 7.1 10.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4400) Cwf_Cwc_15 PF04889.7 CDI74785.1 - 5.4 6.6 27.8 7 6.2 19.3 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF2201_N PF13203.1 CDI74785.1 - 5.7 6.0 31.5 6.7 5.7 21.8 1.0 1 0 0 1 1 1 0 Putative metallopeptidase domain FAM60A PF15396.1 CDI74785.1 - 7.1 6.3 21.4 8.5 6.0 14.8 1.1 1 0 0 1 1 1 0 Protein Family FAM60A XAP5 PF04921.9 CDI74785.1 - 7.5 6.0 22.0 11 5.5 15.3 1.2 1 0 0 1 1 1 0 XAP5, circadian clock regulator NPR3 PF03666.8 CDI74785.1 - 9 4.7 22.1 11 4.3 15.3 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 TFIIF_alpha PF05793.7 CDI74785.1 - 9.3 4.4 24.1 12 4.1 16.7 1.0 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Daxx PF03344.10 CDI74785.1 - 9.4 4.5 32.8 11 4.3 22.7 1.1 1 0 0 1 1 1 0 Daxx Family SR-25 PF10500.4 CDI74786.1 - 0.0075 15.7 18.2 0.0075 15.7 12.6 3.8 2 1 1 4 4 4 2 Nuclear RNA-splicing-associated protein Sex_peptide PF08138.6 CDI74787.1 - 0.51 10.2 0.4 1.7 8.5 0.3 1.9 1 0 0 1 1 1 0 Sex peptide (SP) family Spt20 PF12090.3 CDI74787.1 - 5.6 6.2 27.8 2.9 7.2 0.1 3.8 3 0 0 3 3 3 0 Spt20 family DUF4175 PF13779.1 CDI74788.1 - 0.00083 17.1 25.3 0.00085 17.1 17.5 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4175) TFIIF_alpha PF05793.7 CDI74788.1 - 0.012 13.9 12.3 0.015 13.7 8.5 1.0 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Pet20 PF08692.5 CDI74788.1 - 0.048 13.6 3.6 0.041 13.8 1.9 1.4 1 1 0 1 1 1 0 Mitochondrial protein Pet20 ATAD4 PF15321.1 CDI74788.1 - 0.11 13.4 12.4 0.27 12.2 6.4 2.2 2 0 0 2 2 2 0 ATPase family AAA domain containing 4 Daxx PF03344.10 CDI74788.1 - 0.14 10.6 16.5 0.16 10.4 11.4 1.0 1 0 0 1 1 1 0 Daxx Family Mem_trans PF03547.13 CDI74788.1 - 0.19 10.0 4.6 0.21 9.8 3.2 1.1 1 0 0 1 1 1 0 Membrane transport protein FimP PF09766.4 CDI74788.1 - 0.21 10.6 21.2 0.31 10.0 14.7 1.3 1 0 0 1 1 1 0 Fms-interacting protein Draxin PF15550.1 CDI74788.1 - 0.38 10.3 11.1 0.48 10.0 7.7 1.1 1 0 0 1 1 1 0 Draxin Serinc PF03348.10 CDI74788.1 - 0.53 8.9 7.9 0.59 8.7 5.5 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) NPR3 PF03666.8 CDI74788.1 - 0.58 8.6 11.0 0.75 8.2 7.6 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Bud13 PF09736.4 CDI74788.1 - 0.59 10.3 20.2 0.84 9.8 14.0 1.2 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex Plasmodium_Vir PF05795.6 CDI74788.1 - 0.59 9.2 4.5 0.7 9.0 3.1 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Ycf1 PF05758.7 CDI74788.1 - 0.63 7.6 14.6 0.74 7.4 10.1 1.0 1 0 0 1 1 1 0 Ycf1 Pex16 PF08610.5 CDI74788.1 - 0.64 8.9 13.6 0.81 8.6 9.4 1.1 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) Hid1 PF12722.2 CDI74788.1 - 0.77 7.3 14.0 0.82 7.2 9.7 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Hus1 PF04005.7 CDI74788.1 - 0.98 8.3 6.3 1.3 7.9 4.4 1.1 1 0 0 1 1 1 0 Hus1-like protein SLD3 PF08639.5 CDI74788.1 - 1.1 7.7 17.3 1.5 7.3 12.0 1.1 1 0 0 1 1 1 0 DNA replication regulator SLD3 OATP PF03137.15 CDI74788.1 - 1.2 7.0 6.0 1.3 6.9 4.2 1.2 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family eIF-3_zeta PF05091.7 CDI74788.1 - 1.8 7.1 15.3 2.1 6.8 10.6 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF3597 PF12200.3 CDI74788.1 - 1.8 8.9 14.2 4.8 7.5 1.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3597) Sporozoite_P67 PF05642.6 CDI74788.1 - 1.9 6.2 10.5 2.6 5.8 7.3 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF775 PF05603.7 CDI74788.1 - 2.2 7.7 10.4 3.9 6.9 7.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF775) Gag_p17 PF00540.13 CDI74788.1 - 2.2 8.0 8.3 0.83 9.4 1.5 2.1 2 0 0 2 2 2 0 gag gene protein p17 (matrix protein) WASH-7_C PF14746.1 CDI74788.1 - 2.2 7.8 8.2 3.2 7.3 5.7 1.3 1 0 0 1 1 1 0 WASH complex subunit 7, C-terminal DUF912 PF06024.7 CDI74788.1 - 2.3 8.2 7.4 3.2 7.8 4.1 1.9 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Anoctamin PF04547.7 CDI74788.1 - 3.4 6.2 7.2 3.8 6.0 5.0 1.1 1 0 0 1 1 1 0 Calcium-activated chloride channel Ndc1_Nup PF09531.5 CDI74788.1 - 3.8 5.8 11.2 4.3 5.6 7.8 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup SAPS PF04499.10 CDI74788.1 - 4.3 5.8 12.6 5 5.6 8.7 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF4045 PF13254.1 CDI74788.1 - 4.4 6.4 16.9 5.7 6.1 11.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) FAM60A PF15396.1 CDI74788.1 - 5 6.8 10.2 6.1 6.5 7.1 1.2 1 0 0 1 1 1 0 Protein Family FAM60A PH_4 PF15404.1 CDI74788.1 - 5.3 6.5 11.2 6.3 6.2 6.7 1.7 2 0 0 2 2 2 0 Pleckstrin homology domain Herpes_env PF01673.13 CDI74788.1 - 5.8 5.3 10.1 7.2 5.0 7.0 1.1 1 0 0 1 1 1 0 Herpesvirus putative major envelope glycoprotein Fmp27 PF10344.4 CDI74788.1 - 6.2 4.3 8.0 7.2 4.1 5.5 1.1 1 0 0 1 1 1 0 Mitochondrial protein from FMP27 CDC45 PF02724.9 CDI74788.1 - 6.4 4.6 14.5 7.5 4.4 10.0 1.1 1 0 0 1 1 1 0 CDC45-like protein Asp-B-Hydro_N PF05279.6 CDI74788.1 - 6.4 6.5 15.0 7.8 6.2 10.4 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region DUF3408 PF11888.3 CDI74788.1 - 7 6.5 16.5 1.7 8.5 6.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3408) Folate_carrier PF01770.13 CDI74788.1 - 7.1 5.0 6.8 9.2 4.6 4.7 1.2 1 0 0 1 1 1 0 Reduced folate carrier KfrA_N PF11740.3 CDI74788.1 - 7.2 7.0 32.2 5.2 7.5 2.9 2.2 2 0 0 2 2 2 0 Plasmid replication region DNA-binding N-term Spt20 PF12090.3 CDI74789.1 - 5.8 6.2 16.6 0.57 9.5 2.9 2.6 2 0 0 2 2 2 0 Spt20 family ABC_tran PF00005.22 CDI74790.1 - 8.8e-20 71.4 37.7 5.2e-11 42.9 23.9 6.5 5 2 0 5 5 3 2 ABC transporter AAA_21 PF13304.1 CDI74790.1 - 1.7e-15 57.7 0.4 0.00018 21.6 0.1 3.1 3 0 0 3 3 3 3 AAA domain AAA_29 PF13555.1 CDI74790.1 - 4.5e-10 38.8 0.0 0.00059 19.3 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain SMC_N PF02463.14 CDI74790.1 - 1.2e-09 37.7 21.7 1.5e-07 30.9 6.6 3.1 3 1 0 3 3 2 2 RecF/RecN/SMC N terminal domain FtsK_SpoIIIE PF01580.13 CDI74790.1 - 3.2e-08 33.2 0.8 0.0006 19.3 0.1 2.9 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_25 PF13481.1 CDI74790.1 - 9.5e-08 31.6 1.0 0.00033 20.1 0.2 3.1 3 0 0 3 3 2 2 AAA domain AAA_17 PF13207.1 CDI74790.1 - 9.7e-08 32.8 0.0 0.0008 20.2 0.1 2.6 2 0 0 2 2 2 2 AAA domain MobB PF03205.9 CDI74790.1 - 3.7e-07 29.9 0.0 0.01 15.5 0.0 3.0 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_19 PF13245.1 CDI74790.1 - 5.1e-07 29.3 0.1 0.001 18.7 0.0 5.2 4 2 0 4 4 3 2 Part of AAA domain cobW PF02492.14 CDI74790.1 - 1.3e-06 27.9 0.2 0.03 13.7 0.0 3.1 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain Miro PF08477.8 CDI74790.1 - 2.4e-06 28.0 5.4 0.00096 19.6 1.8 4.5 4 1 1 5 5 2 2 Miro-like protein MMR_HSR1 PF01926.18 CDI74790.1 - 7.1e-06 25.9 0.0 0.089 12.7 0.0 3.2 2 0 0 2 2 2 2 50S ribosome-binding GTPase RNA_helicase PF00910.17 CDI74790.1 - 1.8e-05 24.8 0.5 0.062 13.4 0.0 3.3 2 0 0 2 2 2 2 RNA helicase Arch_ATPase PF01637.13 CDI74790.1 - 2.1e-05 24.3 0.3 0.18 11.4 0.0 2.6 2 0 0 2 2 2 2 Archaeal ATPase NTPase_1 PF03266.10 CDI74790.1 - 4.7e-05 23.1 0.2 0.17 11.6 0.1 2.8 2 0 0 2 2 2 2 NTPase IstB_IS21 PF01695.12 CDI74790.1 - 0.00012 21.5 6.6 0.0024 17.3 1.3 4.3 5 0 0 5 5 3 2 IstB-like ATP binding protein PduV-EutP PF10662.4 CDI74790.1 - 0.00013 21.4 5.4 0.038 13.4 0.1 3.1 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation AAA_23 PF13476.1 CDI74790.1 - 0.00015 22.1 4.1 0.0039 17.5 0.1 8.6 7 2 2 9 9 6 3 AAA domain SR-25 PF10500.4 CDI74790.1 - 0.00016 21.2 12.4 0.00016 21.2 8.6 7.0 6 1 0 6 6 5 1 Nuclear RNA-splicing-associated protein AAA_15 PF13175.1 CDI74790.1 - 0.00032 19.8 8.2 0.21 10.6 0.0 3.7 3 2 1 4 4 4 2 AAA ATPase domain Pox_A32 PF04665.7 CDI74790.1 - 0.00092 18.5 0.0 1.2 8.4 0.0 2.6 2 0 0 2 2 2 2 Poxvirus A32 protein T2SE PF00437.15 CDI74790.1 - 0.001 18.0 2.9 0.001 18.0 2.0 4.0 3 1 1 4 4 4 2 Type II/IV secretion system protein AAA_5 PF07728.9 CDI74790.1 - 0.0019 17.9 9.9 0.41 10.3 0.0 4.1 4 1 0 4 4 4 2 AAA domain (dynein-related subfamily) NACHT PF05729.7 CDI74790.1 - 0.0028 17.3 0.2 0.0028 17.3 0.2 5.5 5 1 0 5 5 4 2 NACHT domain Septin PF00735.13 CDI74790.1 - 0.0032 16.5 0.5 0.0032 16.5 0.3 5.3 4 1 1 5 5 4 2 Septin AAA PF00004.24 CDI74790.1 - 0.0055 16.8 14.3 0.1 12.7 0.0 4.4 4 1 0 4 4 3 2 ATPase family associated with various cellular activities (AAA) SbcCD_C PF13558.1 CDI74790.1 - 0.0076 16.1 0.1 0.0076 16.1 0.1 6.0 5 3 1 6 6 3 1 Putative exonuclease SbcCD, C subunit AAA_18 PF13238.1 CDI74790.1 - 0.01 16.1 10.0 0.029 14.6 0.1 4.2 3 2 0 3 3 2 0 AAA domain AAA_14 PF13173.1 CDI74790.1 - 0.012 15.5 8.2 0.44 10.4 0.0 3.7 4 0 0 4 4 3 0 AAA domain AAA_33 PF13671.1 CDI74790.1 - 0.012 15.4 0.3 0.012 15.4 0.2 7.2 4 2 1 5 5 3 0 AAA domain AAA_22 PF13401.1 CDI74790.1 - 0.032 14.3 0.0 0.032 14.3 0.0 5.4 4 2 3 7 7 5 0 AAA domain GTP_EFTU PF00009.22 CDI74790.1 - 0.037 13.4 0.1 0.037 13.4 0.0 4.9 5 1 0 5 5 4 0 Elongation factor Tu GTP binding domain PRK PF00485.13 CDI74790.1 - 0.17 11.4 12.4 0.6 9.6 2.0 3.1 3 0 0 3 3 2 0 Phosphoribulokinase / Uridine kinase family UPF0079 PF02367.12 CDI74790.1 - 0.19 11.3 10.2 0.67 9.6 0.1 3.4 3 1 0 3 3 2 0 Uncharacterised P-loop hydrolase UPF0079 Dynamin_N PF00350.18 CDI74790.1 - 0.29 10.9 0.0 0.29 10.9 0.0 8.2 4 4 2 6 6 3 0 Dynamin family ATP_bind_1 PF03029.12 CDI74790.1 - 0.52 9.8 13.5 0.89 9.0 0.0 4.1 4 1 1 5 5 4 0 Conserved hypothetical ATP binding protein TPIP1 PF15338.1 CDI74791.1 - 0.069 13.0 0.3 0.15 11.8 0.2 1.4 1 1 1 2 2 2 0 p53-regulated apoptosis-inducing protein 1 DUF2360 PF10152.4 CDI74792.1 - 0.006 16.8 4.4 0.0079 16.4 3.0 1.2 1 0 0 1 1 1 1 Predicted coiled-coil domain-containing protein (DUF2360) Herpes_DNAp_acc PF04929.7 CDI74792.1 - 0.14 11.1 1.0 0.16 10.8 0.7 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor WD40 PF00400.27 CDI74795.1 - 1e-14 53.7 0.6 6.6e-09 35.3 0.1 2.5 2 0 0 2 2 2 2 WD domain, G-beta repeat Nucleoporin_N PF08801.6 CDI74795.1 - 0.049 12.3 0.0 0.061 12.0 0.0 1.2 1 0 0 1 1 1 0 Nup133 N terminal like SIM_C PF06621.7 CDI74795.1 - 0.05 13.1 0.2 0.067 12.7 0.2 1.1 1 0 0 1 1 1 0 Single-minded protein C-terminus Gp58 PF07902.6 CDI74795.1 - 0.14 10.3 0.0 0.21 9.7 0.0 1.2 1 0 0 1 1 1 0 gp58-like protein Lipase_3 PF01764.20 CDI74796.1 - 3.3e-18 65.6 0.0 6.4e-18 64.7 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.2 CDI74796.1 - 0.00037 20.4 1.7 0.00072 19.5 0.2 2.2 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CDI74796.1 - 0.019 14.7 0.2 0.085 12.6 0.0 2.1 3 0 0 3 3 3 0 Alpha/beta hydrolase family PGAP1 PF07819.8 CDI74796.1 - 0.034 13.7 0.0 0.073 12.6 0.0 1.5 1 0 0 1 1 1 0 PGAP1-like protein DUF676 PF05057.9 CDI74796.1 - 0.038 13.2 0.0 0.13 11.5 0.0 1.7 2 0 0 2 2 2 0 Putative serine esterase (DUF676) Porphobil_deam PF01379.15 CDI74796.1 - 0.22 10.4 0.0 0.41 9.5 0.0 1.3 1 0 0 1 1 1 0 Porphobilinogen deaminase, dipyromethane cofactor binding domain Pkinase PF00069.20 CDI74797.1 - 5.4e-41 140.4 0.0 2.9e-12 46.2 0.0 4.3 4 0 0 4 4 4 4 Protein kinase domain Pkinase_Tyr PF07714.12 CDI74797.1 - 8.5e-20 70.9 0.0 6.7e-13 48.2 0.0 2.9 2 1 0 2 2 2 2 Protein tyrosine kinase EF-hand_1 PF00036.27 CDI74797.1 - 1.9e-08 33.0 0.0 0.0051 16.0 0.0 3.1 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.1 CDI74797.1 - 9e-07 28.9 0.0 0.15 12.1 0.0 3.5 4 0 0 4 4 4 2 EF-hand domain pair EF-hand_6 PF13405.1 CDI74797.1 - 6.3e-06 25.6 0.6 0.13 12.2 0.1 3.7 3 0 0 3 3 3 2 EF-hand domain EF-hand_5 PF13202.1 CDI74797.1 - 4.7e-05 22.5 0.1 0.26 10.7 0.0 2.6 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.1 CDI74797.1 - 0.0016 18.0 0.2 0.18 11.4 0.1 3.6 4 0 0 4 4 4 1 EF-hand domain pair HIT PF01230.18 CDI74798.1 - 3.8e-15 56.1 2.2 2e-06 28.2 0.0 2.2 1 1 1 2 2 2 2 HIT domain DcpS_C PF11969.3 CDI74798.1 - 1.6e-06 28.3 1.4 0.0014 18.8 0.0 2.1 1 1 1 2 2 2 2 Scavenger mRNA decapping enzyme C-term binding AAA PF00004.24 CDI74800.1 - 1.8e-88 293.4 0.0 1.4e-46 157.9 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) CDC48_N PF02359.13 CDI74800.1 - 5.8e-23 80.6 0.6 1.2e-22 79.6 0.4 1.6 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain CDC48_2 PF02933.12 CDI74800.1 - 7.7e-10 38.2 0.0 1.6e-09 37.2 0.0 1.6 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 AAA_2 PF07724.9 CDI74800.1 - 3.4e-09 36.8 0.0 1.9e-06 27.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 CDI74800.1 - 1e-08 35.4 0.1 5.3e-05 23.3 0.0 3.9 2 2 0 2 2 2 1 AAA domain AAA_17 PF13207.1 CDI74800.1 - 2e-08 35.0 0.0 1e-05 26.2 0.0 2.8 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.7 CDI74800.1 - 2.2e-08 33.4 0.0 6.6e-06 25.3 0.0 2.7 2 1 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_33 PF13671.1 CDI74800.1 - 1e-07 31.9 0.0 1.5e-05 24.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 CDI74800.1 - 2e-07 31.1 0.1 0.00014 21.9 0.0 3.5 2 2 1 3 3 3 1 AAA ATPase domain AAA_14 PF13173.1 CDI74800.1 - 3.3e-07 30.2 0.0 0.00028 20.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 CDI74800.1 - 8.5e-07 28.7 0.1 1.8e-05 24.4 0.0 3.0 2 2 0 2 2 2 1 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.7 CDI74800.1 - 2.6e-05 23.4 0.0 0.0046 16.0 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin TIP49 PF06068.8 CDI74800.1 - 9.2e-05 21.3 0.1 0.00058 18.6 0.0 2.0 2 0 0 2 2 2 1 TIP49 C-terminus Vps4_C PF09336.5 CDI74800.1 - 0.00015 21.6 0.1 0.0038 17.0 0.0 2.4 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain AAA_18 PF13238.1 CDI74800.1 - 0.00023 21.4 0.0 0.022 15.0 0.0 2.8 3 0 0 3 3 2 1 AAA domain AAA_25 PF13481.1 CDI74800.1 - 0.00027 20.3 3.2 0.16 11.3 0.0 3.3 2 2 1 3 3 3 2 AAA domain AAA_19 PF13245.1 CDI74800.1 - 0.00046 19.8 1.2 0.018 14.8 0.4 3.1 2 0 0 2 2 2 1 Part of AAA domain Cytidylate_kin2 PF13189.1 CDI74800.1 - 0.00083 19.3 0.1 0.51 10.2 0.0 2.7 3 0 0 3 3 2 1 Cytidylate kinase-like family NACHT PF05729.7 CDI74800.1 - 0.00097 18.8 0.1 1.7 8.2 0.0 3.8 3 1 0 4 4 4 1 NACHT domain ResIII PF04851.10 CDI74800.1 - 0.0017 18.1 0.0 0.012 15.4 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Arch_ATPase PF01637.13 CDI74800.1 - 0.0025 17.5 0.1 0.051 13.2 0.0 2.7 2 2 1 3 3 3 1 Archaeal ATPase RNA_helicase PF00910.17 CDI74800.1 - 0.003 17.6 0.0 0.31 11.2 0.0 2.6 2 0 0 2 2 2 1 RNA helicase AAA_28 PF13521.1 CDI74800.1 - 0.0031 17.4 0.0 0.087 12.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain Sigma54_activ_2 PF14532.1 CDI74800.1 - 0.0035 17.3 0.0 0.041 13.9 0.0 2.2 2 0 0 2 2 2 1 Sigma-54 interaction domain SKI PF01202.17 CDI74800.1 - 0.0043 16.9 0.1 6.9 6.5 0.0 3.1 3 0 0 3 3 3 0 Shikimate kinase Viral_helicase1 PF01443.13 CDI74800.1 - 0.0047 16.4 0.0 0.51 9.8 0.0 2.3 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase Mg_chelatase PF01078.16 CDI74800.1 - 0.0073 15.4 0.2 0.047 12.8 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.12 CDI74800.1 - 0.012 15.0 0.1 0.092 12.1 0.0 2.1 2 0 0 2 2 2 0 IstB-like ATP binding protein NB-ARC PF00931.17 CDI74800.1 - 0.039 12.8 0.1 0.29 9.9 0.0 2.0 2 0 0 2 2 2 0 NB-ARC domain KaiC PF06745.8 CDI74800.1 - 0.04 13.0 1.4 3 6.9 0.0 2.6 2 1 1 3 3 2 0 KaiC KAP_NTPase PF07693.9 CDI74800.1 - 0.046 12.7 0.0 2.4 7.0 0.0 2.7 2 1 1 3 3 3 0 KAP family P-loop domain ABC_tran PF00005.22 CDI74800.1 - 0.047 13.9 0.0 1.4 9.2 0.0 2.8 2 1 0 2 2 2 0 ABC transporter Sigma54_activat PF00158.21 CDI74800.1 - 0.068 12.6 0.1 1.3 8.5 0.0 2.9 3 1 0 3 3 2 0 Sigma-54 interaction domain AAA_24 PF13479.1 CDI74800.1 - 0.12 11.9 0.2 0.31 10.5 0.0 1.7 2 0 0 2 2 1 0 AAA domain UPF0079 PF02367.12 CDI74800.1 - 0.13 11.8 0.0 5.7 6.5 0.0 2.9 3 0 0 3 3 3 0 Uncharacterised P-loop hydrolase UPF0079 PhoH PF02562.11 CDI74800.1 - 0.14 11.3 0.2 3.7 6.7 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein NTPase_1 PF03266.10 CDI74800.1 - 0.18 11.5 0.7 30 4.2 0.0 3.6 3 0 0 3 3 3 0 NTPase PGM_PMM_I PF02878.11 CDI74801.1 - 4.1e-27 94.3 0.0 7.2e-27 93.5 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.11 CDI74801.1 - 1e-25 89.9 0.0 2.5e-25 88.7 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.11 CDI74801.1 - 7.1e-10 39.1 0.2 6.7e-09 36.0 0.0 2.7 3 0 0 3 3 3 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.15 CDI74801.1 - 9.1e-06 25.5 0.0 3.6e-05 23.6 0.0 2.1 2 1 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain Vfa1 PF08432.5 CDI74802.1 - 0.053 13.5 5.4 0.065 13.2 3.7 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Striatin PF08232.7 CDI74802.1 - 0.15 12.3 6.1 0.18 12.0 4.2 1.2 1 0 0 1 1 1 0 Striatin family FAM60A PF15396.1 CDI74802.1 - 0.28 10.8 12.2 0.34 10.6 8.5 1.1 1 0 0 1 1 1 0 Protein Family FAM60A Zip PF02535.17 CDI74802.1 - 0.39 9.6 7.2 0.43 9.5 5.0 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Cwf_Cwc_15 PF04889.7 CDI74802.1 - 0.53 9.9 9.6 0.61 9.7 6.7 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF3449 PF11931.3 CDI74802.1 - 0.71 9.3 4.4 0.88 9.0 3.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3449) MRP-S31 PF15433.1 CDI74802.1 - 0.8 9.0 8.8 0.94 8.8 6.1 1.0 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 Gag_spuma PF03276.9 CDI74802.1 - 2 6.6 10.4 2.2 6.4 7.2 1.1 1 0 0 1 1 1 0 Spumavirus gag protein Neur_chan_memb PF02932.11 CDI74802.1 - 2.3 8.0 7.3 2.5 7.9 5.1 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF1510 PF07423.6 CDI74802.1 - 2.3 7.5 10.7 2.6 7.3 7.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DUF2215 PF10225.4 CDI74802.1 - 2.3 7.5 7.9 2.7 7.3 5.5 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) CobT PF06213.7 CDI74802.1 - 2.3 7.2 8.2 2.7 7.0 5.7 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT P30 PF07390.6 CDI74802.1 - 2.7 7.4 13.5 3.3 7.1 9.4 1.3 1 0 0 1 1 1 0 Mycoplasma P30 protein Hid1 PF12722.2 CDI74802.1 - 3.2 5.3 17.8 3.6 5.1 12.3 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Raftlin PF15250.1 CDI74802.1 - 3.2 6.1 8.3 3.6 6.0 5.8 1.0 1 0 0 1 1 1 0 Raftlin Band_3_cyto PF07565.8 CDI74802.1 - 3.5 7.0 7.6 4.1 6.8 5.3 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Spc7_N PF15402.1 CDI74802.1 - 4 5.3 23.1 4.7 5.0 16.0 1.0 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 Rifin_STEVOR PF02009.11 CDI74802.1 - 5.1 6.6 6.5 6.3 6.3 4.5 1.1 1 0 0 1 1 1 0 Rifin/stevor family Na_trans_assoc PF06512.8 CDI74802.1 - 6.4 6.6 10.5 7 6.5 7.3 1.1 1 0 0 1 1 1 0 Sodium ion transport-associated AUX_IAA PF02309.11 CDI74802.1 - 9.1 5.9 10.0 11 5.7 7.0 1.2 1 0 0 1 1 1 0 AUX/IAA family DUF566 PF04484.7 CDI74802.1 - 9.2 5.6 22.7 12 5.2 15.7 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF566) AAA_23 PF13476.1 CDI74803.1 - 0.35 11.1 19.9 0.23 11.7 10.2 2.1 2 0 0 2 2 2 0 AAA domain BTV_NS2 PF04514.7 CDI74803.1 - 5.9 5.6 18.1 1 8.1 10.2 1.6 2 0 0 2 2 2 0 Bluetongue virus non-structural protein NS2 TFIIA PF03153.8 CDI74804.1 - 2.2e-05 24.5 21.1 2.8e-05 24.2 14.6 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Folate_carrier PF01770.13 CDI74804.1 - 0.003 16.1 4.0 0.003 16.1 2.8 1.4 2 0 0 2 2 2 1 Reduced folate carrier Ycf1 PF05758.7 CDI74804.1 - 0.023 12.4 9.8 0.03 12.0 6.8 1.1 1 0 0 1 1 1 0 Ycf1 RNA_pol_Rpb1_5 PF04998.12 CDI74804.1 - 0.088 12.0 3.7 4 6.6 4.5 1.8 2 0 0 2 2 2 0 RNA polymerase Rpb1, domain 5 Zip PF02535.17 CDI74804.1 - 0.25 10.2 8.1 0.46 9.4 5.6 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter VAD1-2 PF15310.1 CDI74804.1 - 3.1 7.4 25.4 5.2 6.6 17.6 1.2 1 0 0 1 1 1 0 Vitamin A-deficiency (VAD) rat model signalling PIG-S PF10510.4 CDI74804.1 - 4.2 5.9 20.8 6.8 5.2 14.4 1.2 1 0 0 1 1 1 0 Phosphatidylinositol-glycan biosynthesis class S protein Peptidase_S49_N PF08496.5 CDI74804.1 - 8.3 6.1 16.5 1.7 8.4 6.5 2.3 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Rifin_STEVOR PF02009.11 CDI74805.1 - 0.0017 18.0 9.0 0.0017 18.0 6.2 9.2 4 2 2 9 9 9 1 Rifin/stevor family MACPF PF01823.14 CDI74805.1 - 0.0022 17.6 0.1 0.0022 17.6 0.0 9.6 5 2 7 12 12 12 1 MAC/Perforin domain Sex_peptide PF08138.6 CDI74805.1 - 5.2 6.9 5.4 5.6 6.8 0.2 3.2 2 0 0 2 2 2 0 Sex peptide (SP) family Peptidase_S49_N PF08496.5 CDI74807.1 - 0.00043 20.1 1.9 0.0005 19.8 1.3 1.0 1 0 0 1 1 1 1 Peptidase family S49 N-terminal Med15 PF09606.5 CDI74807.1 - 0.00086 17.6 19.0 0.0009 17.5 13.2 1.0 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal Shisa PF13908.1 CDI74807.1 - 0.0083 16.3 2.4 0.0086 16.2 1.7 1.0 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator Spt20 PF12090.3 CDI74807.1 - 0.025 13.9 2.7 0.022 14.1 1.8 1.1 1 0 0 1 1 1 0 Spt20 family FimP PF09766.4 CDI74807.1 - 0.039 13.0 9.7 0.04 12.9 6.7 1.0 1 0 0 1 1 1 0 Fms-interacting protein RAB3GAP2_N PF14655.1 CDI74807.1 - 0.073 12.0 4.6 0.081 11.9 3.2 1.1 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus SID-1_RNA_chan PF13965.1 CDI74807.1 - 0.084 11.0 0.6 0.087 10.9 0.4 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Serinc PF03348.10 CDI74807.1 - 0.092 11.4 3.2 0.095 11.3 2.2 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) R_equi_Vir PF05526.6 CDI74807.1 - 0.16 11.5 7.0 0.21 11.2 4.8 1.1 1 0 0 1 1 1 0 Rhodococcus equi virulence-associated protein Peptidase_S15 PF02129.13 CDI74807.1 - 0.29 10.4 4.7 0.32 10.3 3.3 1.0 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Gastrin PF00918.12 CDI74807.1 - 0.34 11.7 7.8 0.42 11.4 5.4 1.1 1 0 0 1 1 1 0 Gastrin/cholecystokinin family Ctr PF04145.10 CDI74807.1 - 1.2 9.1 5.0 2 8.4 3.5 1.3 1 1 0 1 1 1 0 Ctr copper transporter family SR-25 PF10500.4 CDI74808.1 - 0.0032 16.9 7.3 0.0032 16.9 5.1 3.1 3 0 0 3 3 3 1 Nuclear RNA-splicing-associated protein CytochromB561_N PF09786.4 CDI74808.1 - 7 4.9 29.2 8 4.7 20.2 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal SOBP PF15279.1 CDI74808.1 - 7.7 6.7 20.8 11 6.3 14.4 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein Sporozoite_P67 PF05642.6 CDI74809.1 - 0.35 8.6 5.1 0.51 8.1 3.5 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Lamp PF01299.12 CDI74809.1 - 0.5 9.4 0.0 0.5 9.4 0.0 2.3 1 1 1 2 2 2 0 Lysosome-associated membrane glycoprotein (Lamp) Pex14_N PF04695.8 CDI74809.1 - 2.2 8.3 9.1 17 5.4 6.3 2.1 1 1 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Pkinase PF00069.20 CDI74810.1 - 8.4e-08 31.6 0.1 1.6e-06 27.4 0.0 2.6 2 0 0 2 2 2 1 Protein kinase domain CDK2AP PF09806.4 CDI74810.1 - 0.00087 19.5 7.5 0.00087 19.5 5.2 5.2 3 1 0 3 3 3 1 Cyclin-dependent kinase 2-associated protein IncA PF04156.9 CDI74810.1 - 0.0015 18.1 1.6 0.0015 18.1 1.1 3.4 3 1 0 3 3 3 1 IncA protein OmpH PF03938.9 CDI74811.1 - 0.00086 19.2 11.0 0.00086 19.2 7.6 7.4 5 2 0 5 5 5 1 Outer membrane protein (OmpH-like) AAA_23 PF13476.1 CDI74811.1 - 0.063 13.5 0.0 0.063 13.5 0.0 4.8 4 1 0 4 4 4 0 AAA domain Spt20 PF12090.3 CDI74812.1 - 0.043 13.1 12.9 0.31 10.3 2.7 2.4 2 0 0 2 2 2 0 Spt20 family PH_4 PF15404.1 CDI74812.1 - 8 5.9 14.4 5.1 6.5 2.2 2.3 2 0 0 2 2 2 0 Pleckstrin homology domain DUF3353 PF11833.3 CDI74813.1 - 0.0069 15.8 5.9 0.0083 15.6 4.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3353) FimP PF09766.4 CDI74813.1 - 0.018 14.0 19.9 0.02 13.9 13.8 1.0 1 0 0 1 1 1 0 Fms-interacting protein NARP1 PF12569.3 CDI74813.1 - 0.05 12.3 7.0 0.047 12.4 4.8 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DUF2347 PF09804.4 CDI74813.1 - 0.1 11.8 7.5 0.13 11.5 5.2 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2347) Gti1_Pac2 PF09729.4 CDI74813.1 - 0.12 12.2 3.6 0.13 12.1 2.5 1.1 1 0 0 1 1 1 0 Gti1/Pac2 family Ctr PF04145.10 CDI74813.1 - 0.13 12.2 3.6 0.17 11.9 2.5 1.2 1 0 0 1 1 1 0 Ctr copper transporter family DUF4407 PF14362.1 CDI74813.1 - 0.2 10.5 11.2 0.26 10.2 7.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Serinc PF03348.10 CDI74813.1 - 0.23 10.1 6.1 0.23 10.1 4.2 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) DDHD PF02862.12 CDI74813.1 - 0.32 10.7 5.5 0.29 10.8 3.8 1.2 1 0 0 1 1 1 0 DDHD domain Tim54 PF11711.3 CDI74813.1 - 0.49 8.9 5.3 0.53 8.8 3.7 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 eIF-3_zeta PF05091.7 CDI74813.1 - 0.5 8.9 11.2 0.47 9.0 7.8 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Draxin PF15550.1 CDI74813.1 - 0.83 9.2 13.3 1 8.9 9.2 1.0 1 0 0 1 1 1 0 Draxin DUF2126 PF09899.4 CDI74813.1 - 1.3 6.9 7.3 1.3 7.0 5.0 1.0 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) Neur_chan_memb PF02932.11 CDI74813.1 - 1.3 8.8 3.5 1.3 8.8 2.4 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region FCP1_C PF09309.5 CDI74813.1 - 1.4 8.1 12.6 1.9 7.7 8.7 1.2 1 0 0 1 1 1 0 FCP1, C-terminal DUF1764 PF08576.5 CDI74813.1 - 1.8 9.4 11.8 3.1 8.6 8.2 1.4 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) BRF1 PF07741.8 CDI74813.1 - 2.8 8.2 11.3 4.8 7.4 7.8 1.5 1 0 0 1 1 1 0 Brf1-like TBP-binding domain PCYCGC PF13798.1 CDI74813.1 - 2.8 7.6 12.4 13 5.3 8.6 2.0 1 1 0 1 1 1 0 Protein of unknown function with PCYCGC motif FHIPEP PF00771.15 CDI74813.1 - 2.8 6.1 11.1 3.7 5.7 7.7 1.2 1 0 0 1 1 1 0 FHIPEP family Anoctamin PF04547.7 CDI74813.1 - 3.6 6.1 8.3 4.1 5.9 5.8 1.2 1 0 0 1 1 1 0 Calcium-activated chloride channel RR_TM4-6 PF06459.7 CDI74813.1 - 4.3 7.1 10.1 4.5 7.0 7.0 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Paramyxo_ncap PF00973.14 CDI74813.1 - 4.6 5.8 6.8 4.1 6.0 4.7 1.0 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein DUF3464 PF11947.3 CDI74813.1 - 5.4 6.4 9.1 6.1 6.2 6.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) Glyco_transf_15 PF01793.11 CDI74813.1 - 6.3 5.6 10.0 6.6 5.5 7.0 1.1 1 0 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase CPSF100_C PF13299.1 CDI74813.1 - 7.7 6.6 9.9 8.7 6.5 6.9 1.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal DUF4647 PF15504.1 CDI74814.1 - 0.06 12.2 20.0 0.066 12.0 13.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4647) Med15 PF09606.5 CDI74814.1 - 0.062 11.4 36.8 0.071 11.3 25.5 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal MIP-T3 PF10243.4 CDI74814.1 - 0.48 8.8 25.3 0.5 8.7 17.5 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 HHV6-IE PF03753.8 CDI74814.1 - 0.62 7.4 12.4 0.69 7.3 8.6 1.0 1 0 0 1 1 1 0 Human herpesvirus 6 immediate early protein CDK5_activator PF03261.10 CDI74814.1 - 0.67 9.2 18.7 0.74 9.0 13.0 1.0 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein DUF4175 PF13779.1 CDI74814.1 - 2.1 5.9 33.8 2.3 5.7 23.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) TFIIA PF03153.8 CDI74814.1 - 2.3 8.0 31.3 2.5 7.9 21.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF1510 PF07423.6 CDI74814.1 - 2.6 7.3 21.2 3.1 7.1 14.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DUF4407 PF14362.1 CDI74814.1 - 2.8 6.8 16.0 2.9 6.7 11.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Adeno_hexon PF01065.14 CDI74814.1 - 2.9 6.6 14.0 3.1 6.5 9.7 1.0 1 0 0 1 1 1 0 Hexon, adenovirus major coat protein, N-terminal domain DUF572 PF04502.8 CDI74814.1 - 3 6.9 22.0 3.3 6.8 15.3 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Plasmodium_Vir PF05795.6 CDI74814.1 - 3 6.9 13.4 3.6 6.6 9.3 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein eIF-3_zeta PF05091.7 CDI74814.1 - 3.2 6.2 21.2 3.7 6.0 14.7 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DDRGK PF09756.4 CDI74814.1 - 3.4 7.0 17.3 4.3 6.7 12.0 1.2 1 0 0 1 1 1 0 DDRGK domain Macoilin PF09726.4 CDI74814.1 - 3.7 5.7 28.7 3.9 5.6 19.9 1.0 1 0 0 1 1 1 0 Transmembrane protein Ycf1 PF05758.7 CDI74814.1 - 4.1 5.0 15.8 4.6 4.8 10.9 1.0 1 0 0 1 1 1 0 Ycf1 Nucleo_P87 PF07267.6 CDI74814.1 - 4.3 5.9 20.4 4.5 5.8 14.1 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 SAPS PF04499.10 CDI74814.1 - 4.6 5.7 18.1 5 5.6 12.6 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein PAT1 PF09770.4 CDI74814.1 - 4.6 5.3 38.4 5 5.2 26.6 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DNA_pol_viral_N PF00242.12 CDI74814.1 - 4.8 6.1 30.0 5.3 5.9 20.8 1.0 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain Borrelia_P83 PF05262.6 CDI74814.1 - 5 5.2 19.4 5.3 5.1 13.5 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Spc7_N PF15402.1 CDI74814.1 - 7.2 4.4 28.0 7.6 4.3 19.4 1.0 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 DUF4638 PF15472.1 CDI74814.1 - 8.1 5.9 18.7 10 5.6 13.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) Membralin PF09746.4 CDI74814.1 - 8.5 5.3 8.6 10 5.0 6.0 1.0 1 0 0 1 1 1 0 Tumour-associated protein Utp14 PF04615.8 CDI74814.1 - 8.6 4.3 25.4 9.3 4.2 17.6 1.0 1 0 0 1 1 1 0 Utp14 protein FAM60A PF15396.1 CDI74814.1 - 8.8 6.0 21.0 12 5.5 14.5 1.2 1 0 0 1 1 1 0 Protein Family FAM60A Peptidase_S64 PF08192.6 CDI74814.1 - 9.2 4.4 22.8 10 4.2 15.8 1.0 1 0 0 1 1 1 0 Peptidase family S64 Dehalogenase PF13486.1 CDI74814.1 - 9.5 5.5 11.6 11 5.3 8.0 1.1 1 0 0 1 1 1 0 Reductive dehalogenase subunit Asp-B-Hydro_N PF05279.6 CDI74814.1 - 9.7 5.9 11.9 12 5.6 8.3 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region AAA_23 PF13476.1 CDI74815.1 - 0.00064 20.0 0.5 0.00064 20.0 0.3 1.4 2 0 0 2 2 2 1 AAA domain DDHD PF02862.12 CDI74815.1 - 0.0047 16.7 6.4 0.0076 16.0 4.4 1.3 1 0 0 1 1 1 1 DDHD domain FHIPEP PF00771.15 CDI74815.1 - 0.16 10.2 1.7 0.22 9.8 1.1 1.1 1 0 0 1 1 1 0 FHIPEP family EphA2_TM PF14575.1 CDI74815.1 - 0.3 11.5 1.3 1.9 8.9 0.9 2.1 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Folate_carrier PF01770.13 CDI74815.1 - 0.61 8.5 3.4 0.9 7.9 2.4 1.2 1 0 0 1 1 1 0 Reduced folate carrier DUF788 PF05620.6 CDI74815.1 - 1.1 9.1 6.7 1.9 8.3 4.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF788) ALG3 PF05208.8 CDI74815.1 - 1.2 8.3 2.7 1.6 7.9 1.9 1.1 1 0 0 1 1 1 0 ALG3 protein SHR3_chaperone PF08229.6 CDI74815.1 - 2.4 7.0 8.6 3.5 6.5 6.0 1.2 1 0 0 1 1 1 0 ER membrane protein SH3 DUF912 PF06024.7 CDI74815.1 - 6.9 6.7 6.1 0.52 10.3 0.7 1.8 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Apt1 PF10351.4 CDI74815.1 - 7.2 5.3 15.4 7.6 5.2 6.1 2.0 2 0 0 2 2 2 0 Golgi-body localisation protein domain PsiA PF06952.6 CDI74816.1 - 0.088 11.8 0.0 0.15 11.0 0.0 1.3 1 0 0 1 1 1 0 PsiA protein Rad4 PF03835.10 CDI74817.1 - 0.00077 18.8 8.2 0.00077 18.8 5.7 6.6 6 2 0 6 6 6 2 Rad4 transglutaminase-like domain RAP PF08373.5 CDI74818.1 - 1.3e-05 24.8 0.0 7.1e-05 22.5 0.0 2.3 1 0 0 1 1 1 1 RAP domain BAF1_ABF1 PF04684.8 CDI74818.1 - 0.00055 18.9 9.5 0.00055 18.9 6.6 16.9 11 5 3 14 14 14 2 BAF1 / ABF1 chromatin reorganising factor SR-25 PF10500.4 CDI74820.1 - 0.0068 15.8 6.6 0.0082 15.6 4.6 1.0 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein DUF1980 PF09323.5 CDI74820.1 - 0.012 15.3 2.8 0.012 15.3 1.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) TMEM51 PF15345.1 CDI74820.1 - 0.016 14.9 5.6 0.016 14.8 3.9 1.1 1 0 0 1 1 1 0 Transmembrane protein 51 FCP1_C PF09309.5 CDI74820.1 - 0.018 14.3 4.5 0.018 14.3 3.1 1.2 1 0 0 1 1 1 0 FCP1, C-terminal DUF4366 PF14283.1 CDI74820.1 - 0.022 14.1 1.9 0.023 14.1 1.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) Med15 PF09606.5 CDI74820.1 - 0.046 11.9 21.0 0.042 12.0 14.5 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Herpes_DNAp_acc PF04929.7 CDI74820.1 - 0.048 12.6 5.9 0.052 12.5 4.1 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor MCPVI PF02993.9 CDI74820.1 - 0.049 13.7 6.8 0.055 13.6 4.7 1.1 1 0 0 1 1 1 0 Minor capsid protein VI SelP_N PF04592.9 CDI74820.1 - 0.061 12.6 3.7 0.066 12.5 2.5 1.0 1 0 0 1 1 1 0 Selenoprotein P, N terminal region RAB3GAP2_N PF14655.1 CDI74820.1 - 0.074 12.0 5.0 0.1 11.5 3.5 1.3 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus FimP PF09766.4 CDI74820.1 - 0.076 12.0 11.5 0.081 11.9 8.0 1.0 1 0 0 1 1 1 0 Fms-interacting protein Neur_chan_memb PF02932.11 CDI74820.1 - 0.09 12.6 1.1 0.1 12.5 0.7 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Gly-zipper_OmpA PF13436.1 CDI74820.1 - 0.091 12.4 10.7 0.12 11.9 7.4 1.3 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain Pex14_N PF04695.8 CDI74820.1 - 0.12 12.3 11.9 0.14 12.1 8.3 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF912 PF06024.7 CDI74820.1 - 0.16 12.0 3.8 0.18 11.8 2.6 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) XRCC4 PF06632.7 CDI74820.1 - 0.18 10.6 5.7 0.17 10.7 4.0 1.0 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 Serinc PF03348.10 CDI74820.1 - 0.19 10.3 6.9 0.21 10.2 4.8 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) FUN14 PF04930.10 CDI74820.1 - 0.2 11.9 0.8 0.24 11.7 0.5 1.1 1 0 0 1 1 1 0 FUN14 family Folate_carrier PF01770.13 CDI74820.1 - 0.23 9.9 3.7 0.25 9.7 2.6 1.0 1 0 0 1 1 1 0 Reduced folate carrier Peptidase_S49_N PF08496.5 CDI74820.1 - 0.24 11.1 6.4 0.28 10.9 4.4 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF702 PF05142.7 CDI74820.1 - 0.27 11.4 10.7 0.32 11.1 7.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF702) IncA PF04156.9 CDI74820.1 - 0.27 10.8 12.6 0.25 10.9 8.3 1.2 1 1 0 1 1 1 0 IncA protein DUF4557 PF15101.1 CDI74820.1 - 0.31 10.8 15.1 0.34 10.7 10.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) OmpH PF03938.9 CDI74820.1 - 0.34 10.8 20.8 0.38 10.6 14.4 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DivIC PF04977.10 CDI74820.1 - 0.34 10.4 11.6 0.41 10.1 8.0 1.2 1 0 0 1 1 1 0 Septum formation initiator Ctr PF04145.10 CDI74820.1 - 0.34 10.9 4.7 0.38 10.8 3.2 1.1 1 0 0 1 1 1 0 Ctr copper transporter family Gag_spuma PF03276.9 CDI74820.1 - 0.35 9.1 11.9 0.35 9.1 8.2 1.0 1 0 0 1 1 1 0 Spumavirus gag protein OsmC PF02566.14 CDI74820.1 - 0.35 11.0 1.9 0.54 10.4 1.3 1.4 1 1 0 1 1 1 0 OsmC-like protein FemAB PF02388.11 CDI74820.1 - 0.36 9.4 8.2 0.36 9.4 5.7 1.0 1 0 0 1 1 1 0 FemAB family Afaf PF15339.1 CDI74820.1 - 0.39 10.2 3.9 0.43 10.1 2.7 1.1 1 0 0 1 1 1 0 Acrosome formation-associated factor DUF2232 PF09991.4 CDI74820.1 - 0.44 9.4 2.2 0.49 9.3 1.5 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) MRP-S26 PF14943.1 CDI74820.1 - 0.49 9.9 11.5 0.57 9.7 8.0 1.1 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 PP_M1 PF03012.9 CDI74820.1 - 0.54 9.5 7.7 0.59 9.4 5.3 1.0 1 0 0 1 1 1 0 Phosphoprotein Gram_pos_anchor PF00746.16 CDI74820.1 - 0.55 10.1 2.9 1.7 8.5 0.2 2.3 2 0 0 2 2 2 0 Gram positive anchor DUF4446 PF14584.1 CDI74820.1 - 0.57 10.0 4.2 0.6 9.9 2.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) Suf PF05843.9 CDI74820.1 - 0.58 9.8 8.8 0.56 9.8 6.1 1.0 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Hep_59 PF07052.6 CDI74820.1 - 0.59 10.5 10.8 0.74 10.2 7.5 1.2 1 0 0 1 1 1 0 Hepatocellular carcinoma-associated antigen 59 Dala_Dala_lig_N PF01820.16 CDI74820.1 - 0.63 10.3 3.4 0.7 10.2 2.3 1.1 1 0 0 1 1 1 0 D-ala D-ala ligase N-terminus DUF106 PF01956.11 CDI74820.1 - 0.69 9.4 3.7 0.76 9.2 2.5 1.1 1 0 0 1 1 1 0 Integral membrane protein DUF106 OATP PF03137.15 CDI74820.1 - 0.71 7.8 3.2 0.71 7.8 2.2 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family ETRAMP PF09716.5 CDI74820.1 - 0.82 9.6 3.1 1.2 9.1 1.7 1.7 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) MRP-S31 PF15433.1 CDI74820.1 - 0.85 8.9 10.7 1 8.7 7.4 1.0 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 Shisa PF13908.1 CDI74820.1 - 0.85 9.7 8.5 0.94 9.6 5.9 1.1 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator RR_TM4-6 PF06459.7 CDI74820.1 - 0.91 9.3 7.9 0.95 9.3 5.4 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF2561 PF10812.3 CDI74820.1 - 0.93 9.0 5.0 1.1 8.8 3.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2561) RNA_pol_Rpb1_5 PF04998.12 CDI74820.1 - 0.99 8.6 5.6 1.2 8.3 3.9 1.0 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 EIIBC-GUT_N PF03612.9 CDI74820.1 - 1.1 8.8 5.5 1 8.9 3.8 1.1 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Spt20 PF12090.3 CDI74820.1 - 1.1 8.5 7.8 1.3 8.3 5.4 1.1 1 0 0 1 1 1 0 Spt20 family HD-ZIP_N PF04618.7 CDI74820.1 - 1.5 9.3 5.7 2 8.9 3.9 1.2 1 0 0 1 1 1 0 HD-ZIP protein N terminus AUX_IAA PF02309.11 CDI74820.1 - 1.6 8.4 6.6 1.6 8.3 4.6 1.0 1 0 0 1 1 1 0 AUX/IAA family PIH1 PF08190.7 CDI74820.1 - 1.6 8.0 11.4 1.8 7.9 7.9 1.1 1 0 0 1 1 1 0 pre-RNA processing PIH1/Nop17 Hid1 PF12722.2 CDI74820.1 - 1.6 6.2 8.0 1.6 6.2 5.6 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DDHD PF02862.12 CDI74820.1 - 1.7 8.3 9.0 1.8 8.2 6.3 1.0 1 0 0 1 1 1 0 DDHD domain DDRGK PF09756.4 CDI74820.1 - 1.7 8.0 12.5 1.9 7.8 8.7 1.1 1 0 0 1 1 1 0 DDRGK domain DUF4175 PF13779.1 CDI74820.1 - 2 6.0 20.6 2.2 5.8 14.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Baculo_PP31 PF05311.6 CDI74820.1 - 2 7.5 8.0 2.2 7.4 5.6 1.1 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) AIF_C PF14721.1 CDI74820.1 - 2.3 8.4 8.0 2.6 8.2 5.6 1.1 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Endonuc_Holl PF10107.4 CDI74820.1 - 3.1 7.4 7.8 3.5 7.2 5.4 1.1 1 0 0 1 1 1 0 Endonuclease related to archaeal Holliday junction resolvase BRF1 PF07741.8 CDI74820.1 - 3.1 8.0 13.7 4.5 7.5 9.5 1.3 1 0 0 1 1 1 0 Brf1-like TBP-binding domain DUF775 PF05603.7 CDI74820.1 - 3.2 7.2 10.2 3.3 7.1 7.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF775) DUF788 PF05620.6 CDI74820.1 - 3.3 7.5 6.7 4.1 7.2 4.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF788) Band_3_cyto PF07565.8 CDI74820.1 - 3.4 7.1 8.2 3.6 7.0 5.7 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain G0-G1_switch_2 PF15103.1 CDI74820.1 - 3.5 7.9 6.5 4.4 7.5 4.5 1.3 1 0 0 1 1 1 0 G0/G1 switch protein 2 DUF3464 PF11947.3 CDI74820.1 - 4.2 6.8 6.0 4.7 6.6 4.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) DUF3675 PF12428.3 CDI74820.1 - 4.9 7.4 5.7 6 7.1 3.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3675) DUF966 PF06136.8 CDI74820.1 - 6.8 6.0 10.8 7.7 5.8 7.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Activator_LAG-3 PF11498.3 CDI74820.1 - 7.8 5.1 26.2 8.4 5.0 18.2 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 DUF4407 PF14362.1 CDI74820.1 - 8 5.3 14.9 9.5 5.0 10.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF3464 PF11947.3 CDI74821.1 - 0.0097 15.3 0.9 0.011 15.2 0.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3464) Peroxin-13_N PF04088.8 CDI74821.1 - 0.02 14.8 1.7 0.022 14.6 1.2 1.2 1 0 0 1 1 1 0 Peroxin 13, N-terminal region DUF4366 PF14283.1 CDI74821.1 - 0.024 14.0 0.7 0.029 13.8 0.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) DcuA_DcuB PF03605.9 CDI74821.1 - 0.024 13.4 0.3 0.028 13.2 0.2 1.0 1 0 0 1 1 1 0 Anaerobic c4-dicarboxylate membrane transporter Consortin_C PF15281.1 CDI74821.1 - 0.031 13.7 1.0 0.04 13.4 0.7 1.2 1 0 0 1 1 1 0 Consortin C-terminus DUF2031 PF09592.5 CDI74821.1 - 0.037 13.1 1.7 0.042 12.9 1.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2031) Plexin_cytopl PF08337.7 CDI74821.1 - 0.038 12.3 4.6 0.039 12.2 3.2 1.0 1 0 0 1 1 1 0 Plexin cytoplasmic RasGAP domain ORC5_C PF14630.1 CDI74821.1 - 0.042 13.2 6.5 0.046 13.1 4.5 1.0 1 0 0 1 1 1 0 Origin recognition complex (ORC) subunit 5 C-terminus DUF912 PF06024.7 CDI74821.1 - 0.043 13.8 4.5 0.084 12.9 3.1 1.5 1 1 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) HCO3_cotransp PF00955.16 CDI74821.1 - 0.055 12.1 2.5 0.059 12.0 1.8 1.0 1 0 0 1 1 1 0 HCO3- transporter family PBP1_TM PF14812.1 CDI74821.1 - 0.057 13.7 0.7 0.083 13.2 0.5 1.2 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Ctr PF04145.10 CDI74821.1 - 0.058 13.4 4.2 0.071 13.1 2.9 1.1 1 0 0 1 1 1 0 Ctr copper transporter family Senescence_reg PF04520.8 CDI74821.1 - 0.058 13.8 0.6 0.061 13.8 0.4 1.1 1 0 0 1 1 1 0 Senescence regulator SKN1 PF03935.10 CDI74821.1 - 0.077 11.1 0.2 0.089 10.9 0.1 1.0 1 0 0 1 1 1 0 Beta-glucan synthesis-associated protein (SKN1) OATP PF03137.15 CDI74821.1 - 0.14 10.1 6.1 0.15 10.0 4.2 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Serinc PF03348.10 CDI74821.1 - 0.14 10.7 5.0 0.17 10.6 3.5 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) RP-C_C PF11800.3 CDI74821.1 - 0.16 11.6 7.1 0.16 11.6 4.9 1.0 1 0 0 1 1 1 0 Replication protein C C-terminal region Anoctamin PF04547.7 CDI74821.1 - 0.17 10.5 3.2 0.19 10.3 2.2 1.0 1 0 0 1 1 1 0 Calcium-activated chloride channel Dala_Dala_lig_N PF01820.16 CDI74821.1 - 0.17 12.2 2.3 0.18 12.0 1.6 1.1 1 0 0 1 1 1 0 D-ala D-ala ligase N-terminus Kei1 PF08552.6 CDI74821.1 - 0.2 11.2 2.1 0.22 11.1 1.5 1.1 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 7tm_1 PF00001.16 CDI74821.1 - 0.23 10.5 1.0 0.25 10.4 0.7 1.2 1 1 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) TraG_N PF07916.6 CDI74821.1 - 0.24 9.7 3.0 0.26 9.6 2.1 1.1 1 0 0 1 1 1 0 TraG-like protein, N-terminal region DUF2232 PF09991.4 CDI74821.1 - 0.34 9.8 5.2 0.4 9.6 3.6 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) CD20 PF04103.10 CDI74821.1 - 0.44 10.4 2.6 0.54 10.1 1.8 1.2 1 0 0 1 1 1 0 CD20-like family Glt_symporter PF03616.9 CDI74821.1 - 0.48 8.8 2.6 0.56 8.6 1.8 1.1 1 0 0 1 1 1 0 Sodium/glutamate symporter DUF4557 PF15101.1 CDI74821.1 - 0.55 10.0 15.0 0.6 9.9 10.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) AIF_C PF14721.1 CDI74821.1 - 0.86 9.8 3.9 1 9.6 2.7 1.1 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term DUF4175 PF13779.1 CDI74821.1 - 0.97 7.0 27.8 1 7.0 19.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Folate_carrier PF01770.13 CDI74821.1 - 1.1 7.7 5.9 1.3 7.4 4.1 1.0 1 0 0 1 1 1 0 Reduced folate carrier Endonuc_Holl PF10107.4 CDI74821.1 - 1.1 8.9 8.1 1.2 8.8 5.6 1.1 1 0 0 1 1 1 0 Endonuclease related to archaeal Holliday junction resolvase OmpH PF03938.9 CDI74821.1 - 1.2 9.0 24.7 1.3 8.9 17.1 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) LMBR1 PF04791.11 CDI74821.1 - 1.2 7.6 5.6 1.3 7.5 3.9 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein Zip PF02535.17 CDI74821.1 - 1.3 7.9 3.7 1.4 7.8 2.6 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter eIF-3_zeta PF05091.7 CDI74821.1 - 1.3 7.5 8.9 1.3 7.5 6.1 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Band_3_cyto PF07565.8 CDI74821.1 - 1.5 8.2 10.8 1.6 8.2 7.5 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain 60KD_IMP PF02096.15 CDI74821.1 - 1.6 8.3 22.5 2.3 7.8 15.6 1.3 1 1 0 1 1 1 0 60Kd inner membrane protein LIM_bind PF01803.11 CDI74821.1 - 1.7 7.7 12.1 1.7 7.7 8.4 1.1 1 0 0 1 1 1 0 LIM-domain binding protein Paramyxo_ncap PF00973.14 CDI74821.1 - 1.9 7.1 5.6 2 7.0 3.9 1.0 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Glyco_transf_15 PF01793.11 CDI74821.1 - 2 7.2 6.4 2.1 7.2 4.4 1.0 1 0 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase EIIBC-GUT_N PF03612.9 CDI74821.1 - 2.1 7.9 4.5 2.4 7.7 3.1 1.2 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Pex14_N PF04695.8 CDI74821.1 - 2.4 8.2 14.8 4.6 7.2 10.3 1.5 1 1 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region SID-1_RNA_chan PF13965.1 CDI74821.1 - 2.4 6.2 5.9 2.5 6.1 4.1 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 TFIIA PF03153.8 CDI74821.1 - 2.8 7.7 18.1 2.8 7.7 12.6 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit BatA PF07584.6 CDI74821.1 - 4.8 7.4 9.0 16 5.7 6.3 2.0 1 1 0 1 1 1 0 Aerotolerance regulator N-terminal DUF106 PF01956.11 CDI74821.1 - 9.6 5.7 8.4 11 5.5 5.9 1.2 1 0 0 1 1 1 0 Integral membrane protein DUF106 TMEM51 PF15345.1 CDI74821.1 - 9.7 5.8 9.9 12 5.5 6.9 1.2 1 0 0 1 1 1 0 Transmembrane protein 51 IPK PF03770.11 CDI74822.1 - 4.3e-10 39.5 0.0 4.3e-10 39.5 0.0 2.5 2 1 0 2 2 2 1 Inositol polyphosphate kinase Spore_coat_CotO PF14153.1 CDI74822.1 - 0.0061 16.0 11.5 0.0061 16.0 7.9 2.2 2 0 0 2 2 2 1 Spore coat protein CotO MIP-T3 PF10243.4 CDI74822.1 - 0.28 9.6 42.5 0.056 11.9 11.1 2.1 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 CAF-1_p150 PF11600.3 CDI74822.1 - 8.4 5.7 54.4 0.087 12.1 13.1 2.1 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal AAA_23 PF13476.1 CDI74824.1 - 0.0057 16.9 6.8 0.0062 16.8 4.7 1.2 1 0 0 1 1 1 1 AAA domain DUF2339 PF10101.4 CDI74824.1 - 0.22 9.7 9.3 0.25 9.5 6.4 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2339) FimP PF09766.4 CDI74824.1 - 0.23 10.5 18.1 0.27 10.2 12.6 1.2 1 0 0 1 1 1 0 Fms-interacting protein Med15 PF09606.5 CDI74824.1 - 0.77 7.8 51.3 0.99 7.5 35.5 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Peptidase_S15 PF02129.13 CDI74824.1 - 1.1 8.6 12.3 1.5 8.1 8.6 1.3 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) OATP PF03137.15 CDI74824.1 - 1.2 7.0 6.6 1.8 6.5 4.6 1.3 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Sporozoite_P67 PF05642.6 CDI74825.1 - 0.00047 18.1 1.0 0.00047 18.1 0.7 2.1 1 1 1 2 2 2 1 Sporozoite P67 surface antigen DUF572 PF04502.8 CDI74825.1 - 0.061 12.5 27.0 0.024 13.8 10.0 2.8 3 0 0 3 3 3 0 Family of unknown function (DUF572) FimP PF09766.4 CDI74825.1 - 0.31 10.0 39.8 0.51 9.3 10.6 3.1 3 0 0 3 3 3 0 Fms-interacting protein PAT1 PF09770.4 CDI74825.1 - 0.37 8.9 52.9 0.36 9.0 31.0 2.1 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 FAM60A PF15396.1 CDI74825.1 - 2.9 7.5 23.4 4.8 6.8 9.7 2.8 3 0 0 3 3 3 0 Protein Family FAM60A FCP1_C PF09309.5 CDI74825.1 - 3.7 6.7 37.8 0.26 10.5 3.3 3.5 3 0 0 3 3 3 0 FCP1, C-terminal Oxidored_q1_C PF01010.14 CDI74825.1 - 4.2 6.8 6.6 7.2 6.0 4.6 1.3 1 0 0 1 1 1 0 NADH-Ubiquinone oxidoreductase (complex I) subunit C-terminus Spt5_N PF11942.3 CDI74825.1 - 8.9 7.0 27.7 0.32 11.6 4.5 3.0 3 0 0 3 3 3 0 Spt5 transcription elongation factor, acidic N-terminal SR-25 PF10500.4 CDI74826.1 - 0.018 14.5 18.5 0.02 14.3 12.8 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein ProSAAS PF07259.7 CDI74826.1 - 0.075 12.5 0.2 0.079 12.4 0.2 1.0 1 0 0 1 1 1 0 ProSAAS precursor CMV_1a PF12467.3 CDI74826.1 - 0.26 11.6 12.5 0.34 11.2 8.6 1.1 1 0 0 1 1 1 0 Cucumber mosaic virus 1a protein family HA2 PF04408.18 CDI74826.1 - 0.41 10.7 4.4 0.6 10.1 3.0 1.4 1 0 0 1 1 1 0 Helicase associated domain (HA2) YL1 PF05764.8 CDI74826.1 - 0.42 10.1 20.1 0.46 10.0 13.9 1.0 1 0 0 1 1 1 0 YL1 nuclear protein GNT-I PF03071.10 CDI74826.1 - 0.46 8.9 7.3 0.52 8.8 5.1 1.0 1 0 0 1 1 1 0 GNT-I family eIF3_subunit PF08597.5 CDI74826.1 - 0.61 9.6 19.5 0.71 9.3 13.5 1.1 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit Pox_Ag35 PF03286.9 CDI74826.1 - 0.65 9.4 16.1 0.74 9.3 11.2 1.0 1 0 0 1 1 1 0 Pox virus Ag35 surface protein SprA-related PF12118.3 CDI74826.1 - 1.1 8.5 18.5 1.2 8.4 12.8 1.0 1 0 0 1 1 1 0 SprA-related family DUF1168 PF06658.7 CDI74826.1 - 1.5 8.2 25.0 2 7.9 17.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) SPOUT_MTase PF02590.12 CDI74826.1 - 2.3 7.9 6.5 2.5 7.8 4.5 1.1 1 0 0 1 1 1 0 Predicted SPOUT methyltransferase SOBP PF15279.1 CDI74826.1 - 2.3 8.5 10.3 2.5 8.4 7.2 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein DUF244 PF03112.9 CDI74826.1 - 3.1 7.3 10.8 3.3 7.2 7.5 1.2 1 0 0 1 1 1 0 Uncharacterized protein family (ORF7) DUF Rtf2 PF04641.7 CDI74826.1 - 3.1 6.9 18.6 3.4 6.8 12.9 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger Vfa1 PF08432.5 CDI74826.1 - 3.1 7.7 18.9 3.6 7.5 13.1 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 PcfK PF14058.1 CDI74826.1 - 3.2 7.9 17.8 3.7 7.6 12.3 1.1 1 0 0 1 1 1 0 PcfK-like protein POP1 PF06978.6 CDI74826.1 - 4 7.0 15.2 5.2 6.6 10.6 1.1 1 0 0 1 1 1 0 Ribonucleases P/MRP protein subunit POP1 Med19 PF10278.4 CDI74826.1 - 4.5 6.8 26.8 2.6 7.6 17.6 1.3 1 1 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 DUF2413 PF10310.4 CDI74826.1 - 5 5.8 18.3 5.7 5.6 12.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) DUF3807 PF12720.2 CDI74826.1 - 5.9 7.0 17.2 7.4 6.7 12.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) Peptidase_U57 PF05582.7 CDI74826.1 - 6.9 5.5 9.8 8.4 5.2 6.8 1.1 1 0 0 1 1 1 0 YabG peptidase U57 HSP90 PF00183.13 CDI74826.1 - 8.4 4.6 15.9 9.1 4.5 11.0 1.0 1 0 0 1 1 1 0 Hsp90 protein PEX11 PF05648.9 CDI74826.1 - 8.9 5.5 6.7 9.3 5.4 4.7 1.2 1 0 0 1 1 1 0 Peroxisomal biogenesis factor 11 (PEX11) Sec62 PF03839.11 CDI74826.1 - 9 5.6 17.4 9.8 5.5 12.1 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 FLO_LFY PF01698.11 CDI74826.1 - 9.6 4.9 13.1 11 4.7 9.0 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein Pol_alpha_B_N PF08418.5 CDI74828.1 - 0.00031 20.3 12.1 0.00036 20.1 8.4 1.1 1 0 0 1 1 1 1 DNA polymerase alpha subunit B N-terminal RskA PF10099.4 CDI74828.1 - 0.0045 16.7 6.2 0.088 12.5 2.3 2.2 2 0 0 2 2 2 1 Anti-sigma-K factor rskA TFIIA PF03153.8 CDI74828.1 - 0.019 14.9 14.2 0.021 14.7 9.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF3373 PF11853.3 CDI74828.1 - 0.03 12.8 2.1 0.036 12.5 1.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) ImcF-related_N PF14331.1 CDI74828.1 - 0.075 11.9 3.9 0.1 11.4 2.7 1.2 1 0 0 1 1 1 0 ImcF-related N-terminal domain CD20 PF04103.10 CDI74828.1 - 0.45 10.4 10.1 2 8.3 2.6 2.4 1 1 1 2 2 2 0 CD20-like family Tetraspannin PF00335.15 CDI74828.1 - 1.1 8.4 10.5 0.93 8.7 6.1 1.7 1 1 0 1 1 1 0 Tetraspanin family DUF4603 PF15376.1 CDI74828.1 - 4.3 4.4 18.6 5.4 4.0 12.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) Na_trans_assoc PF06512.8 CDI74828.1 - 7.1 6.5 12.7 9.8 6.0 8.8 1.1 1 0 0 1 1 1 0 Sodium ion transport-associated GRIN_C PF15235.1 CDI74828.1 - 8.4 6.4 12.5 0.86 9.6 4.2 2.1 1 1 1 2 2 2 0 G protein-regulated inducer of neurite outgrowth C-terminus Dus PF01207.12 CDI74829.1 - 5.6e-11 41.8 22.4 1.2e-10 40.7 12.9 2.7 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) AAA_23 PF13476.1 CDI74829.1 - 0.56 10.4 9.0 1.7 8.9 6.3 1.7 1 1 0 1 1 1 0 AAA domain Med15 PF09606.5 CDI74829.1 - 1.6 6.8 37.1 3.5 5.7 25.7 1.5 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal APG9 PF04109.11 CDI74830.1 - 0.00036 19.5 0.3 0.00043 19.2 0.2 1.1 1 0 0 1 1 1 1 Autophagy protein Apg9 DNA_Packaging PF11053.3 CDI74830.1 - 0.00052 19.6 3.1 0.00088 18.9 2.1 1.3 1 0 0 1 1 1 1 Terminase DNA packaging enzyme DUF4366 PF14283.1 CDI74830.1 - 0.0018 17.7 5.4 0.0025 17.3 3.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4366) SseC PF04888.7 CDI74830.1 - 0.0039 16.5 8.2 0.0039 16.5 5.7 1.8 1 1 1 2 2 2 1 Secretion system effector C (SseC) like family SOBP PF15279.1 CDI74830.1 - 0.015 15.7 12.9 0.018 15.4 9.0 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein DUF506 PF04720.7 CDI74830.1 - 0.015 14.9 6.1 0.022 14.3 4.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF506) ATP-synt_E PF05680.7 CDI74830.1 - 0.018 14.9 4.5 0.018 14.9 3.1 2.3 2 0 0 2 2 2 0 ATP synthase E chain Nuc_sug_transp PF04142.10 CDI74830.1 - 0.032 13.3 0.2 0.05 12.6 0.1 1.4 1 0 0 1 1 1 0 Nucleotide-sugar transporter EspB PF05802.6 CDI74830.1 - 0.14 11.0 11.5 0.17 10.7 8.0 1.2 1 0 0 1 1 1 0 Enterobacterial EspB protein CAF-1_p150 PF11600.3 CDI74830.1 - 0.24 10.7 26.7 0.89 8.8 18.5 1.7 1 1 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal PigN PF04987.9 CDI74830.1 - 0.25 9.9 0.9 0.33 9.5 0.6 1.4 1 0 0 1 1 1 0 Phosphatidylinositolglycan class N (PIG-N) WES_acyltransf PF03007.11 CDI74830.1 - 0.28 10.7 4.8 0.41 10.1 3.3 1.2 1 0 0 1 1 1 0 Wax ester synthase-like Acyl-CoA acyltransferase domain TFIIA PF03153.8 CDI74830.1 - 0.61 9.9 22.5 0.73 9.6 15.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Peroxin-13_N PF04088.8 CDI74830.1 - 0.64 9.9 6.8 0.063 13.2 1.0 2.0 1 1 2 3 3 3 0 Peroxin 13, N-terminal region Corona_nucleoca PF00937.13 CDI74830.1 - 0.82 8.5 26.1 0.019 13.9 13.5 1.5 2 0 0 2 2 2 0 Coronavirus nucleocapsid protein ETRAMP PF09716.5 CDI74830.1 - 1.1 9.3 5.5 7.5 6.5 3.8 2.2 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) NapE PF06796.6 CDI74830.1 - 1.3 8.4 5.6 0.2 10.9 0.5 2.2 2 1 0 2 2 2 0 Periplasmic nitrate reductase protein NapE Dala_Dala_lig_N PF01820.16 CDI74830.1 - 1.4 9.2 9.9 3.7 7.8 6.9 1.8 1 1 0 1 1 1 0 D-ala D-ala ligase N-terminus IncA PF04156.9 CDI74830.1 - 2.6 7.6 25.6 1.8 8.1 11.6 2.1 2 0 0 2 2 2 0 IncA protein Apt1 PF10351.4 CDI74830.1 - 4 6.1 15.0 0.22 10.3 7.0 1.4 2 0 0 2 2 2 0 Golgi-body localisation protein domain DUF4063 PF13272.1 CDI74830.1 - 4.2 7.2 5.0 1.6 8.6 1.6 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF4063) DUF3984 PF13136.1 CDI74830.1 - 5.2 6.2 20.0 0.27 10.4 9.8 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3984) PRP1_N PF06424.7 CDI74830.1 - 9.4 6.5 13.6 0.33 11.2 4.6 1.8 2 0 0 2 2 2 0 PRP1 splicing factor, N-terminal DUF788 PF05620.6 CDI74830.1 - 9.6 6.0 15.1 4.8 7.0 7.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF788) DUF4647 PF15504.1 CDI74830.1 - 9.9 4.8 21.1 7.5 5.2 14.0 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4647) MIP-T3 PF10243.4 CDI74831.1 - 0.00022 19.8 31.1 0.00022 19.8 21.6 2.9 3 0 0 3 3 3 1 Microtubule-binding protein MIP-T3 AUX_IAA PF02309.11 CDI74831.1 - 0.0035 17.1 11.5 0.0035 17.1 8.0 2.3 2 0 0 2 2 2 1 AUX/IAA family Chorion_2 PF03964.10 CDI74831.1 - 0.016 15.6 1.1 0.016 15.6 0.8 7.0 4 2 1 5 5 5 0 Chorion family 2 Sporozoite_P67 PF05642.6 CDI74831.1 - 0.056 11.2 13.5 0.096 10.5 9.4 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen AbiH PF14253.1 CDI74831.1 - 0.063 12.8 5.6 0.15 11.6 3.9 1.5 1 0 0 1 1 1 0 Bacteriophage abortive infection AbiH LMBR1 PF04791.11 CDI74831.1 - 0.16 10.5 5.4 0.25 9.9 3.7 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein Nop14 PF04147.7 CDI74831.1 - 1.3 6.8 32.7 0.74 7.6 2.3 2.2 2 0 0 2 2 2 0 Nop14-like family Zip PF02535.17 CDI74831.1 - 8.2 5.3 8.2 18 4.2 5.7 1.6 1 0 0 1 1 1 0 ZIP Zinc transporter DUF1777 PF08648.7 CDI74831.1 - 8.9 5.9 23.3 1.3 8.7 10.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1777) DUF4164 PF13747.1 CDI74832.1 - 0.099 12.7 12.3 0.073 13.2 7.6 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4164) IncA PF04156.9 CDI74832.1 - 0.11 12.0 27.7 0.14 11.7 19.2 1.3 1 0 0 1 1 1 0 IncA protein APG6 PF04111.7 CDI74832.1 - 0.12 11.3 15.9 0.12 11.4 11.0 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Allexi_40kDa PF05549.6 CDI74832.1 - 0.14 11.4 6.7 0.15 11.3 4.6 1.1 1 0 0 1 1 1 0 Allexivirus 40kDa protein Peptidase_S49_N PF08496.5 CDI74832.1 - 0.21 11.3 10.3 0.24 11.1 7.2 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal RNA_pol_Rpb1_2 PF00623.15 CDI74832.1 - 0.22 11.4 4.2 0.26 11.2 2.9 1.2 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 2 Nuc-transf PF10127.4 CDI74832.1 - 0.23 10.7 6.5 0.25 10.6 4.5 1.0 1 0 0 1 1 1 0 Predicted nucleotidyltransferase Cluap1 PF10234.4 CDI74832.1 - 0.37 9.9 13.8 0.38 9.9 9.6 1.2 1 0 0 1 1 1 0 Clusterin-associated protein-1 PRKCSH-like PF12999.2 CDI74832.1 - 0.41 10.1 7.6 0.49 9.9 5.3 1.1 1 0 0 1 1 1 0 Glucosidase II beta subunit-like Hormone_1 PF00103.15 CDI74832.1 - 0.46 9.8 7.2 0.53 9.5 5.0 1.1 1 0 0 1 1 1 0 Somatotropin hormone family DUF342 PF03961.8 CDI74832.1 - 0.48 8.7 10.3 0.49 8.7 7.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF1943 PF09172.6 CDI74832.1 - 0.5 9.1 5.3 0.58 8.9 3.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1943) IFT57 PF10498.4 CDI74832.1 - 0.74 8.4 19.6 0.94 8.1 13.6 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 PIH1 PF08190.7 CDI74832.1 - 0.84 9.0 13.7 0.86 8.9 9.5 1.1 1 0 0 1 1 1 0 pre-RNA processing PIH1/Nop17 AAA_23 PF13476.1 CDI74832.1 - 0.86 9.8 19.1 0.91 9.8 13.2 1.1 1 0 0 1 1 1 0 AAA domain RE_TdeIII PF09520.5 CDI74832.1 - 0.96 8.6 11.1 1.2 8.4 7.7 1.1 1 0 0 1 1 1 0 Type II restriction endonuclease, TdeIII DUF4446 PF14584.1 CDI74832.1 - 1.1 9.0 6.2 1.4 8.7 4.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) V_ATPase_I PF01496.14 CDI74832.1 - 1.2 6.8 8.1 1.2 6.8 5.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family AAA_11 PF13086.1 CDI74832.1 - 1.4 8.4 13.1 1.5 8.3 9.1 1.1 1 0 0 1 1 1 0 AAA domain Dynamin_N PF00350.18 CDI74832.1 - 1.5 8.5 5.2 1.7 8.4 3.6 1.2 1 0 0 1 1 1 0 Dynamin family DUF4557 PF15101.1 CDI74832.1 - 1.9 8.2 18.9 1.9 8.2 13.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) HCV_NS5a_C PF12941.2 CDI74832.1 - 2.2 7.7 4.7 2.6 7.5 3.3 1.1 1 0 0 1 1 1 0 HCV NS5a protein C-terminal region Hom_end_hint PF05203.11 CDI74832.1 - 2.9 7.5 5.5 2.9 7.5 3.8 1.1 1 0 0 1 1 1 0 Hom_end-associated Hint HlyD_2 PF12700.2 CDI74832.1 - 2.9 6.9 12.2 3 6.9 8.5 1.0 1 0 0 1 1 1 0 HlyD family secretion protein Serinc PF03348.10 CDI74832.1 - 3.4 6.2 8.3 3.6 6.2 5.8 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) Fungal_trans_2 PF11951.3 CDI74832.1 - 3.6 6.0 8.8 5 5.6 6.1 1.2 1 0 0 1 1 1 0 Fungal specific transcription factor domain DUF3810 PF12725.2 CDI74832.1 - 3.8 6.3 7.5 4.2 6.1 5.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) DUF3413 PF11893.3 CDI74832.1 - 4.3 6.1 6.6 7.7 5.3 4.5 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF3413) Cyto_heme_lyase PF01265.12 CDI74832.1 - 4.5 6.7 10.8 5.4 6.5 7.5 1.0 1 0 0 1 1 1 0 Cytochrome c/c1 heme lyase DUF607 PF04678.8 CDI74832.1 - 4.7 7.1 9.0 5.4 6.9 6.2 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF607 DUF3016 PF11454.3 CDI74832.1 - 5.3 6.6 12.4 1.5 8.3 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3016) DUF972 PF06156.8 CDI74832.1 - 5.5 7.3 14.4 8.9 6.7 10.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF972) Band_3_cyto PF07565.8 CDI74832.1 - 6.7 6.1 11.5 7.3 6.0 8.0 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Exonuc_VII_L PF02601.10 CDI74832.1 - 6.9 5.7 14.7 7.2 5.7 10.2 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Cob_adeno_trans PF01923.13 CDI74832.1 - 7.4 6.3 10.6 9.3 6.0 7.3 1.1 1 0 0 1 1 1 0 Cobalamin adenosyltransferase CemA PF03040.9 CDI74832.1 - 7.5 6.0 7.1 7.3 6.1 4.9 1.1 1 0 0 1 1 1 0 CemA family PIG-S PF10510.4 CDI74832.1 - 8.7 4.8 14.3 9.8 4.7 9.9 1.0 1 0 0 1 1 1 0 Phosphatidylinositol-glycan biosynthesis class S protein Med15 PF09606.5 CDI74835.1 - 1.4 7.0 59.3 1.6 6.8 41.1 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal AAA_23 PF13476.1 CDI74835.1 - 3.9 7.7 41.0 2.1 8.6 6.0 2.2 2 0 0 2 2 2 0 AAA domain Activator_LAG-3 PF11498.3 CDI74836.1 - 0.11 11.1 17.1 0.14 10.9 11.9 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 RRM_1 PF00076.17 CDI74837.1 - 3.4e-15 55.4 0.0 7.2e-15 54.3 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) cwf21 PF08312.7 CDI74837.1 - 8.2e-12 44.7 5.1 8.2e-12 44.7 3.6 2.6 2 0 0 2 2 2 1 cwf21 domain RRM_5 PF13893.1 CDI74837.1 - 4.3e-08 32.8 0.0 8.2e-08 31.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CDI74837.1 - 4.2e-07 29.8 0.1 1.1e-06 28.4 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) CTK3 PF12243.3 CDI74837.1 - 0.00017 21.2 0.0 0.00033 20.2 0.0 1.4 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 Surp PF01805.15 CDI74837.1 - 0.00031 20.3 0.2 0.00063 19.3 0.1 1.5 1 0 0 1 1 1 1 Surp module Tubulin PF00091.20 CDI74838.1 - 5.2e-38 131.0 0.0 4.3e-28 98.6 0.0 2.4 1 1 1 2 2 2 2 Tubulin/FtsZ family, GTPase domain Tubulin_2 PF13809.1 CDI74838.1 - 0.0089 15.0 0.1 0.015 14.2 0.1 1.3 1 0 0 1 1 1 1 Tubulin like E1-E2_ATPase PF00122.15 CDI74839.1 - 6.7e-50 169.2 0.1 1.4e-49 168.2 0.0 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 CDI74839.1 - 5.6e-25 89.0 0.1 9.9e-25 88.2 0.1 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 CDI74839.1 - 7e-11 42.6 0.0 1.3e-10 41.7 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 CDI74839.1 - 1.3e-10 40.5 0.0 3.1e-10 39.3 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 CDI74839.1 - 0.0012 18.4 0.1 0.0023 17.5 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 CDI74839.1 - 0.0014 18.5 0.0 0.0031 17.4 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit EF-hand_7 PF13499.1 CDI74841.1 - 4.6e-33 113.1 0.2 1.6e-12 47.4 0.0 4.4 4 0 0 4 4 4 3 EF-hand domain pair EF-hand_8 PF13833.1 CDI74841.1 - 7e-26 89.6 0.0 4.9e-10 38.8 0.0 4.3 3 1 1 4 4 4 4 EF-hand domain pair EF-hand_1 PF00036.27 CDI74841.1 - 8.4e-25 84.1 0.1 2.5e-05 23.2 0.0 6.1 6 0 0 6 6 6 4 EF hand EF-hand_6 PF13405.1 CDI74841.1 - 1.9e-22 77.0 1.3 0.00016 21.2 0.0 6.9 6 0 0 6 6 6 5 EF-hand domain EF-hand_5 PF13202.1 CDI74841.1 - 7.2e-18 63.0 1.7 1.7e-05 23.8 0.0 4.9 4 0 0 4 4 4 3 EF hand HAP2-GCS1 PF10699.4 CDI74841.1 - 2.1e-08 33.9 0.1 8.2e-08 32.0 0.0 2.1 1 0 0 1 1 1 1 Male gamete fusion factor SPARC_Ca_bdg PF10591.4 CDI74841.1 - 0.00061 19.8 0.4 0.025 14.6 0.0 2.9 3 0 0 3 3 3 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_10 PF14788.1 CDI74841.1 - 0.13 11.9 0.0 1.4 8.5 0.0 2.6 2 0 0 2 2 2 0 EF hand EFhand_Ca_insen PF08726.5 CDI74841.1 - 0.15 12.0 0.1 1.2 9.2 0.0 2.4 2 0 0 2 2 2 0 Ca2+ insensitive EF hand Hid1 PF12722.2 CDI74841.1 - 1.6 6.3 5.5 2.3 5.8 3.8 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein MSC PF09402.5 CDI74842.1 - 6.6e-16 57.9 1.8 8.6e-16 57.5 1.3 1.1 1 0 0 1 1 1 1 Man1-Src1p-C-terminal domain LRR_4 PF12799.2 CDI74843.1 - 9.6e-22 76.1 17.0 1.2e-08 34.3 0.5 5.2 3 2 2 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CDI74843.1 - 3.5e-14 52.2 9.9 2.3e-07 30.4 1.8 3.8 2 2 1 3 3 3 3 Leucine rich repeat LRR_1 PF00560.28 CDI74843.1 - 1.2e-07 30.7 17.6 0.26 11.4 0.0 7.4 6 2 0 6 6 6 4 Leucine Rich Repeat LRR_6 PF13516.1 CDI74843.1 - 8.8e-06 25.2 14.0 1.9 8.8 0.0 7.8 7 1 1 8 8 8 2 Leucine Rich repeat LRR_7 PF13504.1 CDI74843.1 - 4.1e-05 23.1 14.0 19 6.0 0.0 7.9 8 1 0 8 8 8 1 Leucine rich repeat LRR_9 PF14580.1 CDI74843.1 - 0.00019 21.0 0.6 0.0022 17.5 0.1 2.2 1 1 1 2 2 2 1 Leucine-rich repeat rve PF00665.21 CDI74846.1 - 2.3e-19 69.6 0.0 6.1e-19 68.2 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.19 CDI74846.1 - 3.9e-11 42.4 0.1 8e-11 41.4 0.1 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain RVT_1 PF00078.22 CDI74846.1 - 1.2e-06 28.0 0.0 2.2e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-H2C2 PF09337.5 CDI74846.1 - 0.04 13.3 0.1 0.097 12.0 0.1 1.7 1 0 0 1 1 1 0 His(2)-Cys(2) zinc finger Asp_protease_2 PF13650.1 CDI74847.1 - 4.8e-08 33.3 0.0 1.1e-07 32.2 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 CDI74847.1 - 8.9e-07 28.6 0.0 2e-06 27.5 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.15 CDI74847.1 - 1.3e-06 28.2 0.0 2.8e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease RVP_2 PF08284.6 CDI74847.1 - 1.8e-06 27.9 0.0 3.5e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.5 CDI74847.1 - 0.0045 16.5 0.0 0.0086 15.6 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease Surface_antigen PF11054.3 CDI74848.1 - 1.6e-44 152.2 6.9 1.1e-42 146.2 4.8 2.0 1 1 0 1 1 1 1 Sporozoite TA4 surface antigen Surface_antigen PF11054.3 CDI74849.1 - 6e-44 150.3 1.9 7.1e-44 150.1 1.3 1.0 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen Surface_antigen PF11054.3 CDI74850.1 - 3e-38 131.6 2.0 3.4e-38 131.4 1.4 1.0 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen Surface_antigen PF11054.3 CDI74851.1 - 1.3e-47 162.3 9.3 1.6e-47 162.0 6.4 1.0 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen Surface_antigen PF11054.3 CDI74852.1 - 4.8e-47 160.4 8.8 5.9e-47 160.1 6.1 1.0 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen Asp_protease PF09668.5 CDI74853.1 - 2.4e-50 169.2 0.0 5.1e-50 168.1 0.0 1.5 2 0 0 2 2 2 1 Aspartyl protease Asp_protease_2 PF13650.1 CDI74853.1 - 2.7e-09 37.3 0.0 5.2e-09 36.4 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease ubiquitin PF00240.18 CDI74853.1 - 3.5e-09 35.9 0.0 7.3e-09 34.8 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family RVP_2 PF08284.6 CDI74853.1 - 1e-06 28.7 0.0 1.9e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 CDI74853.1 - 2.5e-06 27.1 0.0 7.9e-06 25.6 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.15 CDI74853.1 - 0.00022 21.0 0.0 0.00094 19.0 0.0 2.0 1 1 0 1 1 1 1 Retroviral aspartyl protease EzrA PF06160.7 CDI74853.1 - 0.018 13.2 1.5 0.025 12.8 1.1 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA Rad60-SLD PF11976.3 CDI74853.1 - 0.088 12.5 0.0 0.2 11.3 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like DUF2052 PF09747.4 CDI74856.1 - 0.0041 17.0 14.1 0.0048 16.8 9.7 1.1 1 0 0 1 1 1 1 Coiled-coil domain containing protein (DUF2052) Spore_coat_CotO PF14153.1 CDI74856.1 - 0.0071 15.8 12.9 0.0074 15.7 9.0 1.2 1 0 0 1 1 1 1 Spore coat protein CotO Pex16 PF08610.5 CDI74856.1 - 0.021 13.8 10.5 0.023 13.7 7.3 1.1 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) Folate_carrier PF01770.13 CDI74856.1 - 0.023 13.2 7.3 0.027 13.0 5.1 1.0 1 0 0 1 1 1 0 Reduced folate carrier OmpH PF03938.9 CDI74856.1 - 0.025 14.5 29.9 0.029 14.3 20.7 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF2149 PF09919.4 CDI74856.1 - 0.025 14.6 6.3 0.035 14.1 4.4 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2149) DUF912 PF06024.7 CDI74856.1 - 0.044 13.8 6.3 0.07 13.1 4.4 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Peptidase_S66 PF02016.10 CDI74856.1 - 0.045 12.7 1.7 0.052 12.4 1.2 1.1 1 0 0 1 1 1 0 LD-carboxypeptidase Gti1_Pac2 PF09729.4 CDI74856.1 - 0.052 13.4 3.2 0.055 13.3 2.2 1.2 1 0 0 1 1 1 0 Gti1/Pac2 family Ctr PF04145.10 CDI74856.1 - 0.073 13.1 3.1 0.077 13.0 2.1 1.2 1 0 0 1 1 1 0 Ctr copper transporter family Tim54 PF11711.3 CDI74856.1 - 0.075 11.6 4.1 0.074 11.6 2.8 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 FAM176 PF14851.1 CDI74856.1 - 0.089 12.4 2.7 0.12 12.0 1.8 1.2 1 0 0 1 1 1 0 FAM176 family OSTbeta PF15048.1 CDI74856.1 - 0.11 12.5 5.9 0.17 11.9 4.1 1.2 1 0 0 1 1 1 0 Organic solute transporter subunit beta protein PAT1 PF09770.4 CDI74856.1 - 0.12 10.5 37.8 0.11 10.6 26.2 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 AUX_IAA PF02309.11 CDI74856.1 - 0.16 11.7 9.3 0.19 11.4 6.4 1.1 1 0 0 1 1 1 0 AUX/IAA family Band_3_cyto PF07565.8 CDI74856.1 - 0.16 11.4 14.5 0.18 11.3 10.1 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Senescence_reg PF04520.8 CDI74856.1 - 0.26 11.7 4.6 0.26 11.7 3.2 1.3 1 0 0 1 1 1 0 Senescence regulator Herpes_env PF01673.13 CDI74856.1 - 0.26 9.8 6.2 0.27 9.7 4.3 1.0 1 0 0 1 1 1 0 Herpesvirus putative major envelope glycoprotein DUF2561 PF10812.3 CDI74856.1 - 0.31 10.5 1.6 0.4 10.2 1.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2561) Dala_Dala_lig_N PF01820.16 CDI74856.1 - 0.35 11.2 4.1 0.41 10.9 2.8 1.3 1 0 0 1 1 1 0 D-ala D-ala ligase N-terminus DUF4569 PF15133.1 CDI74856.1 - 0.39 10.0 15.1 0.44 9.9 10.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4569) Neur_chan_memb PF02932.11 CDI74856.1 - 0.4 10.5 8.1 0.4 10.5 5.6 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Pal1 PF08316.6 CDI74856.1 - 0.42 11.0 3.4 0.47 10.9 2.4 1.2 1 0 0 1 1 1 0 Pal1 cell morphology protein Peptidase_S49_N PF08496.5 CDI74856.1 - 0.54 10.0 14.7 0.65 9.7 10.2 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal UPF0565 PF10561.4 CDI74856.1 - 0.57 9.0 7.9 0.66 8.8 5.5 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0565 R_equi_Vir PF05526.6 CDI74856.1 - 0.66 9.5 5.1 0.79 9.3 3.6 1.1 1 0 0 1 1 1 0 Rhodococcus equi virulence-associated protein SAGA-Tad1 PF12767.2 CDI74856.1 - 0.68 9.5 16.7 0.76 9.3 11.6 1.1 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit Plasmodium_Vir PF05795.6 CDI74856.1 - 0.84 8.7 2.4 0.79 8.8 1.7 1.0 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Na_trans_assoc PF06512.8 CDI74856.1 - 0.88 9.4 6.9 1 9.3 4.8 1.1 1 0 0 1 1 1 0 Sodium ion transport-associated Serinc PF03348.10 CDI74856.1 - 0.88 8.2 12.5 0.98 8.0 8.6 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) PIH1 PF08190.7 CDI74856.1 - 0.98 8.7 16.4 0.96 8.8 11.4 1.1 1 0 0 1 1 1 0 pre-RNA processing PIH1/Nop17 eIF-3_zeta PF05091.7 CDI74856.1 - 1.2 7.6 17.3 1.2 7.6 12.0 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Nucleoside_tran PF01733.13 CDI74856.1 - 1.5 7.9 4.6 1.8 7.6 3.2 1.1 1 0 0 1 1 1 0 Nucleoside transporter Glyco_transf_15 PF01793.11 CDI74856.1 - 1.7 7.5 10.9 2 7.3 7.6 1.1 1 0 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase Cas1_AcylT PF07779.7 CDI74856.1 - 1.8 6.9 5.9 2 6.7 4.1 1.0 1 0 0 1 1 1 0 10 TM Acyl Transferase domain found in Cas1p TFIIA PF03153.8 CDI74856.1 - 1.9 8.2 28.5 1.9 8.2 19.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Ndc1_Nup PF09531.5 CDI74856.1 - 1.9 6.7 9.9 1.8 6.9 6.9 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup F-protein PF00469.15 CDI74856.1 - 2.1 7.6 12.7 2.4 7.5 8.8 1.1 1 0 0 1 1 1 0 Negative factor, (F-Protein) or Nef FNIP_N PF14636.1 CDI74856.1 - 2.2 8.7 13.5 3 8.3 9.4 1.2 1 0 0 1 1 1 0 Folliculin-interacting protein N-terminus DUF4446 PF14584.1 CDI74856.1 - 2.5 7.9 7.7 3.5 7.4 5.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) Herpes_DNAp_acc PF04929.7 CDI74856.1 - 2.6 6.9 11.4 3 6.7 7.9 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor FAD-SLDH PF12318.3 CDI74856.1 - 2.7 7.6 13.4 3.8 7.1 9.3 1.3 1 0 0 1 1 1 0 Membrane bound FAD containing D-sorbitol dehydrogenase Bul1_N PF04425.7 CDI74856.1 - 2.9 6.3 10.7 3 6.2 7.4 1.1 1 0 0 1 1 1 0 Bul1 N terminus DUF4638 PF15472.1 CDI74856.1 - 3 7.3 9.9 3.1 7.3 6.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) EIIBC-GUT_N PF03612.9 CDI74856.1 - 3.2 7.3 9.8 4.6 6.8 6.8 1.4 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus DUF605 PF04652.11 CDI74856.1 - 3.3 7.0 18.9 3.5 6.9 13.1 1.2 1 0 0 1 1 1 0 Vta1 like DUF1800 PF08811.6 CDI74856.1 - 3.4 6.4 17.0 3.5 6.4 11.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1800) NARP1 PF12569.3 CDI74856.1 - 3.5 6.2 13.7 4.2 6.0 9.5 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Spore_YhcN_YlaJ PF09580.5 CDI74856.1 - 4 7.5 12.2 4.9 7.2 8.5 1.2 1 0 0 1 1 1 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) Totivirus_coat PF05518.6 CDI74856.1 - 4.3 5.0 6.3 4.3 5.0 4.4 1.0 1 0 0 1 1 1 0 Totivirus coat protein FLO_LFY PF01698.11 CDI74856.1 - 4.6 5.9 13.7 5.6 5.7 9.5 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein Ketoacyl-synt_2 PF13723.1 CDI74856.1 - 4.8 6.3 20.4 5.9 6.0 14.1 1.1 1 0 0 1 1 1 0 Beta-ketoacyl synthase, N-terminal domain EIF4E-T PF10477.4 CDI74856.1 - 5.6 5.6 16.1 5.7 5.6 11.1 1.0 1 0 0 1 1 1 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E FimP PF09766.4 CDI74856.1 - 5.8 5.8 28.4 7.7 5.4 19.7 1.2 1 0 0 1 1 1 0 Fms-interacting protein DUF3260 PF11658.3 CDI74856.1 - 5.9 4.9 16.6 7.3 4.6 11.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3260) CPSF100_C PF13299.1 CDI74856.1 - 6 7.0 14.5 7.5 6.7 10.0 1.1 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Zip PF02535.17 CDI74856.1 - 6.9 5.5 6.4 8.4 5.3 4.4 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Peptidase_U57 PF05582.7 CDI74856.1 - 7.3 5.4 11.0 8.6 5.2 7.6 1.1 1 0 0 1 1 1 0 YabG peptidase U57 FAM60A PF15396.1 CDI74856.1 - 7.9 6.1 11.3 9.5 5.9 7.8 1.1 1 0 0 1 1 1 0 Protein Family FAM60A YfhO PF09586.5 CDI74856.1 - 8 4.3 14.7 9.7 4.0 10.2 1.0 1 0 0 1 1 1 0 Bacterial membrane protein YfhO OATP PF03137.15 CDI74856.1 - 8.8 4.2 12.3 11 3.9 8.6 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Conotoxin PF02950.12 CDI74856.1 - 9 7.1 15.5 21 5.9 10.4 1.8 1 1 0 1 1 1 0 Conotoxin FYDLN_acid PF09538.5 CDI74856.1 - 9.1 6.9 8.6 22 5.7 4.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) DUF1764 PF08576.5 CDI74856.1 - 9.1 7.1 18.0 17 6.2 12.5 1.4 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) DUF1980 PF09323.5 CDI74857.1 - 3.1 7.5 8.9 4.5 6.9 6.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) Ctr PF04145.10 CDI74857.1 - 9.8 6.2 10.3 1.7 8.6 3.8 2.1 1 1 1 2 2 2 0 Ctr copper transporter family DUF3523 PF12037.3 CDI74859.1 - 0.0046 15.9 12.3 0.0046 15.9 8.6 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF3523) SpoIIIAH PF12685.2 CDI74859.1 - 0.056 12.9 9.4 0.31 10.4 0.5 2.7 2 0 0 2 2 2 0 SpoIIIAH-like protein Complex1_LYR_2 PF13233.1 CDI74859.1 - 4 7.9 10.6 7.5 7.0 5.7 2.8 2 1 0 2 2 2 0 Complex1_LYR-like AAA_23 PF13476.1 CDI74859.1 - 5.3 7.3 10.2 7 6.9 4.9 2.3 2 0 0 2 2 2 0 AAA domain DUF1840 PF08895.6 CDI74859.1 - 6.4 6.8 11.3 0.053 13.5 1.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF1840) Sin_N PF04801.8 CDI74860.1 - 0.16 10.8 1.4 0.23 10.2 1.0 1.2 1 0 0 1 1 1 0 Sin-like protein conserved region Nha1_C PF08619.5 CDI74860.1 - 8.9 5.4 11.3 1.3 8.2 2.9 2.0 2 0 0 2 2 2 0 Alkali metal cation/H+ antiporter Nha1 C terminus DUF2052 PF09747.4 CDI74861.1 - 0.0029 17.5 14.8 0.0035 17.2 10.3 1.4 1 0 0 1 1 1 1 Coiled-coil domain containing protein (DUF2052) FimP PF09766.4 CDI74861.1 - 0.0058 15.7 17.9 0.0066 15.5 12.4 1.1 1 0 0 1 1 1 1 Fms-interacting protein Gag_spuma PF03276.9 CDI74861.1 - 0.0064 14.8 15.0 0.0066 14.8 10.4 1.2 1 0 0 1 1 1 1 Spumavirus gag protein Pal1 PF08316.6 CDI74861.1 - 0.007 16.8 5.4 0.013 15.9 3.7 1.4 1 0 0 1 1 1 1 Pal1 cell morphology protein DDHD PF02862.12 CDI74861.1 - 0.0076 16.0 9.8 0.0083 15.9 6.8 1.3 1 0 0 1 1 1 1 DDHD domain Hid1 PF12722.2 CDI74861.1 - 0.008 13.9 9.7 0.0079 13.9 6.7 1.0 1 0 0 1 1 1 1 High-temperature-induced dauer-formation protein T4SS-DNA_transf PF02534.9 CDI74861.1 - 0.0091 14.6 4.0 0.011 14.4 2.8 1.0 1 0 0 1 1 1 1 Type IV secretory system Conjugative DNA transfer Band_3_cyto PF07565.8 CDI74861.1 - 0.012 15.1 10.3 0.014 14.8 7.2 1.3 1 0 0 1 1 1 0 Band 3 cytoplasmic domain FAM176 PF14851.1 CDI74861.1 - 0.014 15.1 4.8 0.019 14.6 3.3 1.4 1 0 0 1 1 1 0 FAM176 family PIH1 PF08190.7 CDI74861.1 - 0.018 14.5 12.6 0.019 14.4 8.7 1.1 1 0 0 1 1 1 0 pre-RNA processing PIH1/Nop17 Ycf1 PF05758.7 CDI74861.1 - 0.018 12.7 8.7 0.017 12.9 6.0 1.1 1 0 0 1 1 1 0 Ycf1 ABC2_membrane_2 PF12679.2 CDI74861.1 - 0.023 13.5 1.1 0.029 13.2 0.8 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein DDRGK PF09756.4 CDI74861.1 - 0.068 12.5 20.7 0.1 12.0 14.3 1.2 1 0 0 1 1 1 0 DDRGK domain GAGA_bind PF06217.7 CDI74861.1 - 0.076 12.9 8.7 0.093 12.6 6.0 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family Pex16 PF08610.5 CDI74861.1 - 0.077 11.9 7.7 0.089 11.7 5.4 1.2 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) Gti1_Pac2 PF09729.4 CDI74861.1 - 0.079 12.8 6.2 0.095 12.5 4.3 1.3 1 0 0 1 1 1 0 Gti1/Pac2 family DUF4638 PF15472.1 CDI74861.1 - 0.081 12.5 5.2 0.096 12.2 3.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) eIF-3_zeta PF05091.7 CDI74861.1 - 0.084 11.4 12.4 0.084 11.4 8.6 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Mem_trans PF03547.13 CDI74861.1 - 0.091 11.0 3.3 0.095 10.9 2.3 1.1 1 0 0 1 1 1 0 Membrane transport protein DUF2217 PF10265.4 CDI74861.1 - 0.1 11.3 9.0 0.12 11.1 6.2 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) SGT1 PF07093.6 CDI74861.1 - 0.11 10.8 12.6 0.12 10.7 8.8 1.1 1 0 0 1 1 1 0 SGT1 protein Draxin PF15550.1 CDI74861.1 - 0.12 12.0 9.3 0.14 11.7 6.5 1.1 1 0 0 1 1 1 0 Draxin DUF966 PF06136.8 CDI74861.1 - 0.13 11.6 13.2 0.15 11.4 9.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Plasmodium_Vir PF05795.6 CDI74861.1 - 0.13 11.4 3.5 0.15 11.2 2.4 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein DUF4045 PF13254.1 CDI74861.1 - 0.13 11.4 14.8 0.16 11.2 10.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Raftlin PF15250.1 CDI74861.1 - 0.14 10.6 9.7 0.16 10.4 6.7 1.2 1 0 0 1 1 1 0 Raftlin CRF1 PF10380.4 CDI74861.1 - 0.15 12.4 5.7 0.17 12.2 4.0 1.3 1 0 0 1 1 1 0 Transcription factor CRF1 DUF2828 PF11443.3 CDI74861.1 - 0.16 10.1 9.0 0.17 10.0 6.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) PH_4 PF15404.1 CDI74861.1 - 0.16 11.4 8.4 0.22 11.0 5.8 1.3 1 0 0 1 1 1 0 Pleckstrin homology domain DNA_pol_viral_N PF00242.12 CDI74861.1 - 0.18 10.8 8.6 0.2 10.6 6.0 1.0 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain Membralin PF09746.4 CDI74861.1 - 0.18 10.7 3.3 0.19 10.7 2.3 1.1 1 0 0 1 1 1 0 Tumour-associated protein YfhO PF09586.5 CDI74861.1 - 0.27 9.2 5.5 0.32 8.9 3.8 1.0 1 0 0 1 1 1 0 Bacterial membrane protein YfhO SID-1_RNA_chan PF13965.1 CDI74861.1 - 0.27 9.3 5.7 0.31 9.1 3.9 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 PLRV_ORF5 PF01690.12 CDI74861.1 - 0.28 10.3 15.4 0.33 10.0 10.7 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein DUF4642 PF15484.1 CDI74861.1 - 0.28 11.1 12.5 0.39 10.6 8.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4642) AAA_11 PF13086.1 CDI74861.1 - 0.28 10.7 10.6 0.31 10.5 7.3 1.2 1 0 0 1 1 1 0 AAA domain NPR3 PF03666.8 CDI74861.1 - 0.3 9.5 10.5 0.4 9.1 7.3 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Afi1 PF07792.7 CDI74861.1 - 0.31 11.0 14.2 0.49 10.4 9.8 1.3 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking YABBY PF04690.8 CDI74861.1 - 0.33 11.1 6.4 0.38 10.9 4.4 1.3 1 0 0 1 1 1 0 YABBY protein AUX_IAA PF02309.11 CDI74861.1 - 0.34 10.6 10.1 0.38 10.4 7.0 1.2 1 0 0 1 1 1 0 AUX/IAA family Dynamin_N PF00350.18 CDI74861.1 - 0.34 10.6 4.2 0.38 10.5 2.9 1.3 1 0 0 1 1 1 0 Dynamin family Neur_chan_memb PF02932.11 CDI74861.1 - 0.39 10.5 8.6 0.43 10.4 5.9 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region SHR3_chaperone PF08229.6 CDI74861.1 - 0.4 9.6 16.5 0.81 8.6 11.5 1.6 1 0 0 1 1 1 0 ER membrane protein SH3 Glt_symporter PF03616.9 CDI74861.1 - 0.4 9.1 2.0 0.58 8.5 1.4 1.3 1 0 0 1 1 1 0 Sodium/glutamate symporter FAM60A PF15396.1 CDI74861.1 - 0.46 10.2 8.5 0.54 9.9 5.9 1.2 1 0 0 1 1 1 0 Protein Family FAM60A F-protein PF00469.15 CDI74861.1 - 0.46 9.8 9.0 0.49 9.7 6.3 1.2 1 0 0 1 1 1 0 Negative factor, (F-Protein) or Nef UPF0560 PF10577.4 CDI74861.1 - 0.47 8.6 21.2 0.58 8.3 14.7 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Hom_end_hint PF05203.11 CDI74861.1 - 0.52 10.0 9.2 0.79 9.4 6.4 1.3 1 0 0 1 1 1 0 Hom_end-associated Hint Ppx-GppA PF02541.11 CDI74861.1 - 0.53 9.4 7.9 0.67 9.1 5.5 1.1 1 0 0 1 1 1 0 Ppx/GppA phosphatase family POP1 PF06978.6 CDI74861.1 - 0.55 9.8 9.6 0.73 9.4 6.7 1.3 1 0 0 1 1 1 0 Ribonucleases P/MRP protein subunit POP1 DUF106 PF01956.11 CDI74861.1 - 0.59 9.6 8.8 0.71 9.3 6.1 1.3 1 0 0 1 1 1 0 Integral membrane protein DUF106 DUF1266 PF06889.6 CDI74861.1 - 0.63 9.8 14.2 0.83 9.4 9.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1266) G-7-MTase PF12803.2 CDI74861.1 - 0.68 9.0 5.2 0.83 8.7 3.6 1.1 1 0 0 1 1 1 0 mRNA (guanine-7-)methyltransferase (G-7-MTase) SAPS PF04499.10 CDI74861.1 - 0.81 8.2 13.1 0.86 8.1 9.1 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF3381 PF11861.3 CDI74861.1 - 1 8.8 15.5 1.4 8.3 10.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) Cellulose_synt PF03552.9 CDI74861.1 - 1 7.5 4.6 1.1 7.4 3.2 1.0 1 0 0 1 1 1 0 Cellulose synthase DUF4175 PF13779.1 CDI74861.1 - 1.1 6.9 44.7 1.2 6.7 31.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) MCPVI PF02993.9 CDI74861.1 - 1.4 8.9 14.8 1.6 8.8 10.2 1.1 1 0 0 1 1 1 0 Minor capsid protein VI DUF2215 PF10225.4 CDI74861.1 - 1.5 8.2 5.9 1.8 7.9 4.1 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) Glyco_transf_15 PF01793.11 CDI74861.1 - 1.5 7.6 11.7 1.8 7.3 8.1 1.2 1 0 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase NHase_beta PF02211.10 CDI74861.1 - 1.6 8.3 10.6 0.4 10.3 5.1 1.6 1 1 1 2 2 2 0 Nitrile hydratase beta subunit Sporozoite_P67 PF05642.6 CDI74861.1 - 1.7 6.4 10.0 1.7 6.3 6.9 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Otopetrin PF03189.8 CDI74861.1 - 1.8 7.4 6.5 2 7.3 4.5 1.1 1 0 0 1 1 1 0 Otopetrin Baculo_PP31 PF05311.6 CDI74861.1 - 2 7.6 12.5 2.7 7.2 8.7 1.2 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) RED_N PF07808.8 CDI74861.1 - 2.2 7.4 19.5 3.6 6.7 13.5 1.4 1 0 0 1 1 1 0 RED-like protein N-terminal region TFIIA PF03153.8 CDI74861.1 - 2.2 8.0 31.2 2.8 7.7 21.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PAT1 PF09770.4 CDI74861.1 - 2.5 6.2 33.5 2.7 6.0 23.2 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 OATP PF03137.15 CDI74861.1 - 2.6 5.9 8.9 3.3 5.6 6.2 1.2 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family XRN_N PF03159.13 CDI74861.1 - 2.7 7.3 7.3 3.5 6.9 5.1 1.2 1 0 0 1 1 1 0 XRN 5'-3' exonuclease N-terminus MMR1 PF08505.5 CDI74861.1 - 2.7 7.9 18.6 3.1 7.7 12.9 1.2 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein DUF1675 PF07897.6 CDI74861.1 - 4.7 6.9 11.7 5.6 6.7 8.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) FliP PF00813.15 CDI74861.1 - 5 6.7 7.9 5.5 6.6 5.4 1.3 1 0 0 1 1 1 0 FliP family Herpes_env PF01673.13 CDI74861.1 - 5.1 5.5 14.5 5.9 5.3 10.1 1.1 1 0 0 1 1 1 0 Herpesvirus putative major envelope glycoprotein Peptidase_S64 PF08192.6 CDI74861.1 - 5.2 5.2 15.3 6.1 5.0 10.6 1.0 1 0 0 1 1 1 0 Peptidase family S64 Senescence_reg PF04520.8 CDI74861.1 - 5.7 7.4 13.6 7.9 6.9 9.4 1.3 1 0 0 1 1 1 0 Senescence regulator Glyco_transf_6 PF03414.8 CDI74861.1 - 6 5.2 8.4 7.5 4.8 5.8 1.1 1 0 0 1 1 1 0 Glycosyltransferase family 6 GOLD_2 PF13897.1 CDI74861.1 - 6 7.0 7.2 10 6.3 5.0 1.4 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking Peptidase_U57 PF05582.7 CDI74861.1 - 6.6 5.6 10.1 8.2 5.2 7.0 1.2 1 0 0 1 1 1 0 YabG peptidase U57 DUF3573 PF12097.3 CDI74861.1 - 6.6 5.2 8.0 6.5 5.2 5.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) Endonuc_Holl PF10107.4 CDI74861.1 - 6.8 6.3 14.7 11 5.6 10.2 1.4 1 0 0 1 1 1 0 Endonuclease related to archaeal Holliday junction resolvase FemAB PF02388.11 CDI74861.1 - 7.2 5.1 18.4 8.2 4.9 12.8 1.1 1 0 0 1 1 1 0 FemAB family Asp-B-Hydro_N PF05279.6 CDI74861.1 - 9 6.0 17.6 12 5.6 12.2 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region 5_nucleotid PF05761.9 CDI74861.1 - 9.2 4.6 11.7 11 4.3 8.1 1.1 1 0 0 1 1 1 0 5' nucleotidase family Chromo PF00385.19 CDI74862.1 - 0.00094 18.8 0.0 0.0019 17.8 0.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Bac_DnaA PF00308.13 CDI74862.1 - 0.0022 17.6 0.2 0.011 15.3 0.1 2.3 1 0 0 1 1 1 1 Bacterial dnaA protein Metallothio_11 PF02066.10 CDI74864.1 - 0.16 11.8 18.9 1.5 8.7 3.4 2.8 2 0 0 2 2 2 0 Metallothionein family 11 SPX PF03105.14 CDI74865.1 - 7.4 6.2 34.9 0.041 13.6 6.2 3.2 1 1 1 2 2 2 0 SPX domain Ribosomal_L12 PF00542.14 CDI74866.1 - 0.65 10.0 10.9 20 5.2 0.1 4.9 5 0 0 5 5 5 0 Ribosomal protein L7/L12 C-terminal domain DUF2126 PF09899.4 CDI74867.1 - 0.011 13.8 7.8 0.018 13.1 5.4 1.3 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) Suf PF05843.9 CDI74867.1 - 0.012 15.3 14.7 0.022 14.5 10.2 1.4 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Phage_int_SAM_5 PF13102.1 CDI74867.1 - 0.012 15.5 3.5 0.024 14.6 2.4 1.5 1 0 0 1 1 1 0 Phage integrase SAM-like domain FimP PF09766.4 CDI74867.1 - 0.31 10.0 21.7 0.54 9.2 15.0 1.3 1 0 0 1 1 1 0 Fms-interacting protein Gag_spuma PF03276.9 CDI74867.1 - 4.8 5.3 25.3 11 4.1 17.5 1.5 1 0 0 1 1 1 0 Spumavirus gag protein DUF912 PF06024.7 CDI74867.1 - 5.9 6.9 9.0 3.1 7.8 4.3 1.9 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Baculo_PP31 PF05311.6 CDI74867.1 - 8.3 5.5 13.1 6.6 5.9 8.1 1.5 2 0 0 2 2 2 0 Baculovirus 33KDa late protein (PP31) LicD PF04991.8 CDI74869.1 - 0.099 12.7 3.0 0.13 12.3 2.1 1.1 1 0 0 1 1 1 0 LicD family RR_TM4-6 PF06459.7 CDI74869.1 - 0.35 10.7 28.6 0.4 10.5 19.9 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 MRP-S31 PF15433.1 CDI74869.1 - 0.67 9.3 29.4 0.72 9.2 20.4 1.0 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 Rtf2 PF04641.7 CDI74869.1 - 0.95 8.6 25.3 1.1 8.4 17.6 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger Pox_Ag35 PF03286.9 CDI74869.1 - 1.7 8.1 19.6 2 7.8 13.6 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DUF1510 PF07423.6 CDI74869.1 - 1.8 7.8 33.8 2.2 7.5 23.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) FNIP_N PF14636.1 CDI74869.1 - 2.3 8.7 30.3 2.7 8.4 21.0 1.1 1 0 0 1 1 1 0 Folliculin-interacting protein N-terminus GAGA_bind PF06217.7 CDI74869.1 - 2.9 7.7 31.7 3.3 7.5 22.0 1.0 1 0 0 1 1 1 0 GAGA binding protein-like family PLRV_ORF5 PF01690.12 CDI74869.1 - 3.2 6.7 26.0 3.2 6.7 18.0 1.0 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein DUF4045 PF13254.1 CDI74869.1 - 3.3 6.9 27.6 3.7 6.7 19.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Herpes_DNAp_acc PF04929.7 CDI74869.1 - 3.5 6.5 24.5 3.7 6.3 17.0 1.0 1 0 0 1 1 1 0 Herpes DNA replication accessory factor CDC45 PF02724.9 CDI74869.1 - 4.3 5.2 33.0 4.8 5.0 22.9 1.0 1 0 0 1 1 1 0 CDC45-like protein TFIIA PF03153.8 CDI74869.1 - 5.1 6.8 48.5 5.9 6.6 33.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF2347 PF09804.4 CDI74869.1 - 5.9 6.0 15.1 7.1 5.8 10.5 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2347) DUF2052 PF09747.4 CDI74869.1 - 6.3 6.6 37.2 7.4 6.4 25.8 1.1 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) DUF605 PF04652.11 CDI74869.1 - 6.6 6.0 36.6 8.3 5.6 25.4 1.1 1 0 0 1 1 1 0 Vta1 like ARGLU PF15346.1 CDI74869.1 - 7.9 6.2 43.1 10 5.8 29.9 1.1 1 0 0 1 1 1 0 Arginine and glutamate-rich 1 Raftlin PF15250.1 CDI74869.1 - 9.7 4.5 28.0 11 4.4 19.4 1.1 1 0 0 1 1 1 0 Raftlin CTP_transf_2 PF01467.21 CDI74872.1 - 0.019 15.0 0.0 0.047 13.7 0.0 1.7 2 0 0 2 2 2 0 Cytidylyltransferase NTP_transf_3 PF12804.2 CDI74873.1 - 3.2e-13 50.0 0.0 8.3e-13 48.7 0.0 1.8 1 1 0 1 1 1 1 MobA-like NTP transferase domain NTP_transferase PF00483.18 CDI74873.1 - 2.2e-12 46.8 0.0 5e-12 45.6 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.19 CDI74873.1 - 0.00019 20.7 0.2 0.067 12.7 0.0 2.9 1 1 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) CTP_transf_3 PF02348.14 CDI74873.1 - 0.15 11.6 0.0 0.3 10.6 0.0 1.4 1 0 0 1 1 1 0 Cytidylyltransferase BMF PF15185.1 CDI74874.1 - 0.023 14.0 0.1 0.042 13.1 0.1 1.4 1 0 0 1 1 1 0 Bcl-2-modifying factor, apoptosis TPR_11 PF13414.1 CDI74876.1 - 2.2e-05 24.0 9.1 0.027 14.0 0.3 3.6 3 0 0 3 3 3 3 TPR repeat TPR_2 PF07719.12 CDI74876.1 - 0.00037 20.2 3.1 0.25 11.3 0.2 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 CDI74876.1 - 0.0022 17.5 1.0 0.76 9.4 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 CDI74876.1 - 0.0084 16.6 0.8 0.0084 16.6 0.6 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat DUF4569 PF15133.1 CDI74877.1 - 0.0069 15.8 5.5 0.0069 15.8 3.8 2.9 3 0 0 3 3 3 1 Domain of unknown function (DUF4569) EphA2_TM PF14575.1 CDI74877.1 - 0.73 10.2 16.5 3.2 8.2 0.1 5.1 5 0 0 5 5 5 0 Ephrin type-A receptor 2 transmembrane domain SR-25 PF10500.4 CDI74878.1 - 4.5e-05 23.0 20.1 7.3e-05 22.3 13.9 1.3 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein DUF3984 PF13136.1 CDI74878.1 - 0.011 14.9 18.6 0.014 14.6 12.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3984) DUF1675 PF07897.6 CDI74878.1 - 0.25 11.1 22.5 0.29 10.9 15.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) CDC45 PF02724.9 CDI74878.1 - 0.47 8.4 20.7 0.55 8.1 14.3 1.0 1 0 0 1 1 1 0 CDC45-like protein FLO_LFY PF01698.11 CDI74878.1 - 0.5 9.1 21.3 0.62 8.8 14.8 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein Neur_chan_memb PF02932.11 CDI74878.1 - 2.4 7.9 22.9 2.9 7.7 15.8 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Utp14 PF04615.8 CDI74878.1 - 4.2 5.4 27.5 5 5.1 19.1 1.0 1 0 0 1 1 1 0 Utp14 protein DUF2413 PF10310.4 CDI74878.1 - 4.3 6.0 25.2 5.4 5.7 17.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) Corona_nucleoca PF00937.13 CDI74878.1 - 4.7 6.0 29.1 5.9 5.7 20.2 1.0 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein Macoilin PF09726.4 CDI74878.1 - 6.2 4.9 23.3 8.3 4.5 16.2 1.2 1 0 0 1 1 1 0 Transmembrane protein Cwf_Cwc_15 PF04889.7 CDI74878.1 - 6.7 6.3 25.3 9.1 5.9 17.5 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein XAP5 PF04921.9 CDI74878.1 - 6.9 6.1 18.2 8.7 5.8 12.6 1.1 1 0 0 1 1 1 0 XAP5, circadian clock regulator GRA6 PF05084.8 CDI74878.1 - 7 6.1 7.9 8.1 5.9 5.3 1.3 1 1 0 1 1 1 0 Granule antigen protein (GRA6) SAPS PF04499.10 CDI74878.1 - 7.5 5.0 20.7 8.8 4.8 14.3 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF2217 PF10265.4 CDI74878.1 - 8.9 4.9 18.4 11 4.6 12.8 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) AAA_23 PF13476.1 CDI74880.1 - 0.003 17.9 7.7 0.003 17.9 5.3 2.8 2 1 0 2 2 2 1 AAA domain SWIB PF02201.13 CDI74881.1 - 6.9e-20 70.5 0.1 1.1e-19 69.9 0.1 1.3 1 0 0 1 1 1 1 SWIB/MDM2 domain ATAD4 PF15321.1 CDI74881.1 - 2.3 9.2 8.4 19 6.3 2.0 2.4 2 0 0 2 2 2 0 ATPase family AAA domain containing 4 UBA PF00627.26 CDI74883.1 - 0.013 15.2 0.1 0.03 14.1 0.1 1.6 1 0 0 1 1 1 0 UBA/TS-N domain Ycf1 PF05758.7 CDI74883.1 - 0.77 7.4 17.6 0.019 12.7 4.7 2.2 2 0 0 2 2 2 0 Ycf1 Methyltransf_32 PF13679.1 CDI74883.1 - 3.9 7.1 18.5 0.2 11.3 2.8 3.4 3 0 0 3 3 3 0 Methyltransferase domain RAP1 PF07218.6 CDI74884.1 - 1.1 7.3 6.4 1.3 7.0 4.4 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Spore_coat_CotO PF14153.1 CDI74885.1 - 0.00025 20.5 5.2 0.00026 20.5 3.6 1.1 1 0 0 1 1 1 1 Spore coat protein CotO GCC2_GCC3 PF07699.8 CDI74885.1 - 0.00081 18.9 0.6 0.0019 17.7 0.4 1.7 1 0 0 1 1 1 1 GCC2 and GCC3 Plasmodium_Vir PF05795.6 CDI74885.1 - 0.0034 16.6 0.5 0.004 16.4 0.3 1.0 1 0 0 1 1 1 1 Plasmodium vivax Vir protein PBP1_TM PF14812.1 CDI74885.1 - 0.007 16.6 2.6 0.01 16.0 1.8 1.2 1 0 0 1 1 1 1 Transmembrane domain of transglycosylase PBP1 at N-terminal Ycf1 PF05758.7 CDI74885.1 - 0.0083 13.9 2.8 0.0076 14.0 2.0 1.0 1 0 0 1 1 1 1 Ycf1 DUF912 PF06024.7 CDI74885.1 - 0.0096 15.9 4.8 0.018 15.1 3.3 1.3 1 0 0 1 1 1 1 Nucleopolyhedrovirus protein of unknown function (DUF912) IER PF05760.7 CDI74885.1 - 0.0098 15.8 13.8 0.012 15.6 9.6 1.1 1 0 0 1 1 1 1 Immediate early response protein (IER) DUF4366 PF14283.1 CDI74885.1 - 0.012 15.0 6.8 0.012 15.0 4.7 2.0 1 1 1 2 2 1 0 Domain of unknown function (DUF4366) Band_3_cyto PF07565.8 CDI74885.1 - 0.013 15.0 5.1 0.014 14.9 3.5 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Gti1_Pac2 PF09729.4 CDI74885.1 - 0.023 14.5 0.6 0.024 14.5 0.5 1.1 1 0 0 1 1 1 0 Gti1/Pac2 family FimP PF09766.4 CDI74885.1 - 0.023 13.7 16.6 0.028 13.4 11.5 1.1 1 0 0 1 1 1 0 Fms-interacting protein CD20 PF04103.10 CDI74885.1 - 0.029 14.2 0.7 0.029 14.2 0.5 1.5 2 0 0 2 2 1 0 CD20-like family DUF966 PF06136.8 CDI74885.1 - 0.042 13.2 5.0 0.051 12.9 3.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Peroxin-13_N PF04088.8 CDI74885.1 - 0.05 13.5 4.4 0.076 12.9 3.0 1.2 1 0 0 1 1 1 0 Peroxin 13, N-terminal region CDC45 PF02724.9 CDI74885.1 - 0.051 11.6 3.6 0.057 11.4 2.5 1.0 1 0 0 1 1 1 0 CDC45-like protein Hid1 PF12722.2 CDI74885.1 - 0.063 10.9 3.6 0.061 11.0 2.5 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Glyco_transf_15 PF01793.11 CDI74885.1 - 0.087 11.7 5.3 0.11 11.3 3.7 1.1 1 0 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase Cytochrom_B_N PF00033.14 CDI74885.1 - 0.11 11.7 0.2 0.13 11.5 0.2 1.2 1 0 0 1 1 1 0 Cytochrome b(N-terminal)/b6/petB Ni_hydr_CYTB PF01292.15 CDI74885.1 - 0.12 11.7 0.3 0.14 11.5 0.2 1.2 1 0 0 1 1 1 0 Prokaryotic cytochrome b561 Protocadherin PF08374.6 CDI74885.1 - 0.12 11.9 5.7 0.19 11.3 4.0 1.2 1 0 0 1 1 1 0 Protocadherin Neur_chan_memb PF02932.11 CDI74885.1 - 0.12 12.1 1.8 0.13 12.1 1.2 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region OATP PF03137.15 CDI74885.1 - 0.13 10.3 6.5 0.17 9.9 4.5 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Zip PF02535.17 CDI74885.1 - 0.15 11.0 1.0 0.18 10.7 0.7 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter eIF-3_zeta PF05091.7 CDI74885.1 - 0.15 10.6 8.9 0.18 10.3 6.1 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Rxt3 PF08642.5 CDI74885.1 - 0.18 12.0 3.5 0.29 11.4 2.4 1.3 1 0 0 1 1 1 0 Histone deacetylation protein Rxt3 PIH1 PF08190.7 CDI74885.1 - 0.21 10.9 12.5 0.29 10.5 8.7 1.2 1 0 0 1 1 1 0 pre-RNA processing PIH1/Nop17 Serinc PF03348.10 CDI74885.1 - 0.23 10.1 7.0 0.28 9.8 4.9 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) Paramyxo_ncap PF00973.14 CDI74885.1 - 0.41 9.2 4.3 0.46 9.1 3.0 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein DUF4045 PF13254.1 CDI74885.1 - 0.43 9.8 9.4 0.53 9.5 6.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) DDHD PF02862.12 CDI74885.1 - 0.7 9.6 8.6 1 9.0 6.0 1.2 1 0 0 1 1 1 0 DDHD domain MCPVI PF02993.9 CDI74885.1 - 0.75 9.9 18.3 1 9.4 12.7 1.1 1 0 0 1 1 1 0 Minor capsid protein VI Folate_carrier PF01770.13 CDI74885.1 - 0.94 7.9 5.8 1.3 7.4 4.0 1.1 1 0 0 1 1 1 0 Reduced folate carrier Glt_symporter PF03616.9 CDI74885.1 - 1.2 7.5 3.7 1.8 6.9 2.6 1.2 1 0 0 1 1 1 0 Sodium/glutamate symporter SpoVR PF04293.8 CDI74885.1 - 1.2 7.3 9.3 1.6 7.0 6.5 1.1 1 0 0 1 1 1 0 SpoVR like protein EIIBC-GUT_N PF03612.9 CDI74885.1 - 1.3 8.6 8.2 2.6 7.5 5.7 1.4 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus PH_4 PF15404.1 CDI74885.1 - 1.5 8.3 9.2 2.1 7.8 6.4 1.1 1 0 0 1 1 1 0 Pleckstrin homology domain 2OG-FeII_Oxy_5 PF13759.1 CDI74885.1 - 1.6 9.0 5.5 2.6 8.3 3.8 1.3 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase HGTP_anticodon2 PF12745.2 CDI74885.1 - 1.7 7.7 10.7 2.3 7.2 7.4 1.1 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs Ndc1_Nup PF09531.5 CDI74885.1 - 2.6 6.3 8.8 3 6.1 6.1 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF1764 PF08576.5 CDI74885.1 - 2.7 8.8 15.0 5.1 7.9 10.4 1.4 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) LIM_bind PF01803.11 CDI74885.1 - 2.8 6.9 13.1 4.7 6.2 9.1 1.3 1 0 0 1 1 1 0 LIM-domain binding protein Peptidase_S49_N PF08496.5 CDI74885.1 - 3.3 7.4 11.7 4.7 6.9 8.1 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal CDC37_N PF03234.9 CDI74885.1 - 3.7 7.8 17.0 6.7 7.0 11.8 1.3 1 1 0 1 1 1 0 Cdc37 N terminal kinase binding Pol_alpha_B_N PF08418.5 CDI74885.1 - 4.5 6.7 13.0 5.5 6.4 9.0 1.1 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal 60KD_IMP PF02096.15 CDI74885.1 - 4.8 6.7 13.0 6.5 6.3 9.0 1.3 1 0 0 1 1 1 0 60Kd inner membrane protein RR_TM4-6 PF06459.7 CDI74885.1 - 4.8 6.9 13.4 8.6 6.1 9.3 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 G-alpha PF00503.15 CDI74885.1 - 5.3 5.6 14.6 6.7 5.2 10.1 1.1 1 0 0 1 1 1 0 G-protein alpha subunit DUF106 PF01956.11 CDI74885.1 - 9.8 5.6 9.1 13 5.3 6.3 1.1 1 0 0 1 1 1 0 Integral membrane protein DUF106 CAF-1_p150 PF11600.3 CDI74886.1 - 0.043 13.1 34.6 0.047 13.0 24.0 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Ycf1 PF05758.7 CDI74886.1 - 0.087 10.5 23.3 0.081 10.6 16.2 1.0 1 0 0 1 1 1 0 Ycf1 DUF1510 PF07423.6 CDI74886.1 - 0.11 11.8 29.3 0.12 11.7 20.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) AMP-binding PF00501.23 CDI74886.1 - 0.17 10.2 7.2 0.19 10.0 5.0 1.1 1 0 0 1 1 1 0 AMP-binding enzyme U79_P34 PF03064.11 CDI74886.1 - 0.18 11.2 21.0 0.21 11.1 14.5 1.1 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Spore_coat_CotO PF14153.1 CDI74886.1 - 0.59 9.5 38.4 0.71 9.2 26.6 1.3 1 0 0 1 1 1 0 Spore coat protein CotO IncA PF04156.9 CDI74886.1 - 0.6 9.6 50.6 5.6 6.5 35.1 1.9 1 1 0 1 1 1 0 IncA protein AAA_11 PF13086.1 CDI74886.1 - 1.1 8.8 24.1 1.2 8.6 16.7 1.1 1 0 0 1 1 1 0 AAA domain Med15 PF09606.5 CDI74886.1 - 1.1 7.3 91.7 1.3 7.0 63.6 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Caldesmon PF02029.10 CDI74886.1 - 1.2 7.5 27.7 1.3 7.3 19.2 1.1 1 0 0 1 1 1 0 Caldesmon Raftlin PF15250.1 CDI74886.1 - 1.2 7.6 24.1 1.3 7.4 16.7 1.2 1 0 0 1 1 1 0 Raftlin MMR1 PF08505.5 CDI74886.1 - 2.4 8.1 33.5 3 7.8 23.2 1.2 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein PAT1 PF09770.4 CDI74886.1 - 2.7 6.1 66.6 2.8 6.0 46.2 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Peptidase_S15 PF02129.13 CDI74886.1 - 3.5 6.9 25.7 4.8 6.5 17.8 1.3 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) APG6 PF04111.7 CDI74886.1 - 3.7 6.4 37.2 3.8 6.4 25.8 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF4220 PF13968.1 CDI74886.1 - 4.3 6.3 14.3 4.5 6.2 9.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4220) PPP4R2 PF09184.6 CDI74886.1 - 5.3 6.4 22.2 5.7 6.4 15.4 1.1 1 0 0 1 1 1 0 PPP4R2 MSP1_C PF07462.6 CDI74886.1 - 5.4 5.2 19.0 6.4 5.0 13.2 1.1 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus SAPS PF04499.10 CDI74886.1 - 5.6 5.4 25.5 5.3 5.5 17.7 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein HAUS6_N PF14661.1 CDI74886.1 - 8.6 5.6 42.4 9.7 5.4 29.4 1.0 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus DUF2215 PF10225.4 CDI74886.1 - 9.3 5.6 18.1 11 5.3 12.6 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) MRP-S31 PF15433.1 CDI74886.1 - 9.5 5.5 39.1 11 5.3 27.1 1.1 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 Herpes_DNAp_acc PF04929.7 CDI74886.1 - 9.9 5.0 23.3 9.8 5.0 16.2 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Med15 PF09606.5 CDI74888.1 - 0.07 11.3 25.1 0.12 10.5 17.4 1.4 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF853 PF05872.7 CDI74888.1 - 0.66 8.2 10.0 1.1 7.5 6.9 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) DivIC PF04977.10 CDI74888.1 - 8.1 6.0 12.2 14 5.2 8.5 1.3 1 0 0 1 1 1 0 Septum formation initiator DUF1510 PF07423.6 CDI74889.1 - 2.6e-06 26.9 23.3 3.9e-06 26.3 16.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) Neur_chan_memb PF02932.11 CDI74889.1 - 0.00052 19.9 16.9 0.00056 19.8 11.7 1.0 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region DUF2514 PF10721.4 CDI74889.1 - 0.0019 17.9 16.1 0.0019 17.9 11.2 2.0 1 1 1 2 2 1 1 Protein of unknown function (DUF2514) Ycf1 PF05758.7 CDI74889.1 - 0.0088 13.8 26.9 0.0089 13.8 18.7 1.0 1 0 0 1 1 1 1 Ycf1 TMEM154 PF15102.1 CDI74889.1 - 0.016 14.9 1.2 0.016 14.9 0.8 3.6 1 1 1 2 2 1 0 TMEM154 protein family MLANA PF14991.1 CDI74889.1 - 0.019 14.9 1.1 0.019 14.9 0.8 2.3 1 1 1 2 2 1 0 Protein melan-A SID-1_RNA_chan PF13965.1 CDI74889.1 - 0.064 11.4 17.9 0.095 10.8 12.4 1.3 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 HemY_N PF07219.8 CDI74889.1 - 0.51 9.8 10.0 1.2 8.6 6.9 1.8 1 1 0 1 1 1 0 HemY protein N-terminus SpoIIIAH PF12685.2 CDI74889.1 - 0.78 9.1 34.6 2.1 7.7 24.0 1.6 1 1 0 1 1 1 0 SpoIIIAH-like protein Herpes_UL87 PF03043.9 CDI74889.1 - 0.99 7.7 17.3 1.1 7.4 12.0 1.1 1 0 0 1 1 1 0 Herpesvirus UL87 family FAM163 PF15069.1 CDI74889.1 - 1 9.9 14.4 2.8 8.5 10.0 1.6 1 1 0 1 1 1 0 FAM163 family GAGA_bind PF06217.7 CDI74889.1 - 1.3 8.8 35.3 1.5 8.7 24.5 1.0 1 0 0 1 1 1 0 GAGA binding protein-like family KASH PF10541.4 CDI74889.1 - 1.4 8.8 6.3 2 8.3 4.4 1.3 1 0 0 1 1 1 0 Nuclear envelope localisation domain SAGA-Tad1 PF12767.2 CDI74889.1 - 1.5 8.3 41.4 1.7 8.2 28.7 1.0 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit Presenilin PF01080.12 CDI74889.1 - 1.9 7.1 25.6 2.2 7.0 17.8 1.1 1 0 0 1 1 1 0 Presenilin Zip PF02535.17 CDI74889.1 - 2.8 6.8 19.5 12 4.7 13.5 1.8 1 1 0 1 1 1 0 ZIP Zinc transporter CAF-1_p150 PF11600.3 CDI74889.1 - 3.3 7.0 44.4 4.1 6.7 30.8 1.0 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Hid1 PF12722.2 CDI74889.1 - 3.4 5.2 39.7 3.7 5.1 27.5 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Mem_trans PF03547.13 CDI74889.1 - 3.5 5.8 16.6 4.7 5.3 11.5 1.3 1 0 0 1 1 1 0 Membrane transport protein DC_STAMP PF07782.8 CDI74889.1 - 4.8 6.7 11.9 14 5.2 8.3 1.8 1 1 0 1 1 1 0 DC-STAMP-like protein TRAP_alpha PF03896.11 CDI74889.1 - 5.2 5.9 18.3 0.031 13.2 3.1 2.0 1 1 1 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit BatA PF07584.6 CDI74890.1 - 0.0045 17.1 8.8 0.15 12.2 1.0 2.2 2 0 0 2 2 2 2 Aerotolerance regulator N-terminal DUF2116 PF09889.4 CDI74890.1 - 0.096 12.5 0.8 0.096 12.5 0.5 2.9 2 1 1 3 3 3 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) DUF418 PF04235.7 CDI74890.1 - 0.1 12.2 5.9 0.18 11.4 4.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF418) GLYCAM-1 PF05242.6 CDI74890.1 - 0.13 12.2 1.9 0.26 11.2 1.2 1.6 1 1 0 1 1 1 0 Glycosylation-dependent cell adhesion molecule 1 (GlyCAM-1) Cnd1_N PF12922.2 CDI74890.1 - 0.64 9.6 10.0 0.21 11.1 4.6 1.7 1 1 1 2 2 2 0 non-SMC mitotic condensation complex subunit 1, N-term DUF2339 PF10101.4 CDI74890.1 - 8.4 4.5 13.7 9.6 4.3 9.5 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2339) Utp14 PF04615.8 CDI74892.1 - 1.9 6.5 30.1 2.4 6.2 20.9 1.0 1 0 0 1 1 1 0 Utp14 protein DUF572 PF04502.8 CDI74892.1 - 5.1 6.2 40.7 6.9 5.7 28.2 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Hid1 PF12722.2 CDI74892.1 - 6.3 4.3 41.5 9.8 3.7 28.7 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Parvo_coat PF00740.13 CDI74892.1 - 7.6 5.3 24.7 9.2 5.0 17.1 1.0 1 0 0 1 1 1 0 Parvovirus coat protein VP2 Pex14_N PF04695.8 CDI74893.1 - 0.019 15.0 11.1 0.018 15.0 7.7 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Velvet PF11754.3 CDI74893.1 - 0.026 14.1 4.3 0.025 14.1 3.0 1.0 1 0 0 1 1 1 0 Velvet factor DnaJ-X PF14308.1 CDI74893.1 - 0.069 12.4 6.3 0.075 12.3 4.4 1.0 1 0 0 1 1 1 0 X-domain of DnaJ-containing DUF912 PF06024.7 CDI74893.1 - 0.096 12.7 5.2 0.12 12.4 3.6 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) FCP1_C PF09309.5 CDI74893.1 - 0.13 11.5 9.2 0.14 11.4 6.4 1.1 1 0 0 1 1 1 0 FCP1, C-terminal FimP PF09766.4 CDI74893.1 - 0.15 11.1 17.5 0.15 11.0 12.2 1.0 1 0 0 1 1 1 0 Fms-interacting protein Rxt3 PF08642.5 CDI74893.1 - 0.18 12.0 3.9 0.2 11.9 2.7 1.1 1 0 0 1 1 1 0 Histone deacetylation protein Rxt3 MRP-S26 PF14943.1 CDI74893.1 - 0.19 11.2 8.4 0.21 11.1 5.8 1.1 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 DUF2722 PF10846.3 CDI74893.1 - 0.23 10.4 12.9 0.27 10.2 8.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) PBP1_TM PF14812.1 CDI74893.1 - 0.24 11.7 1.9 0.3 11.4 1.3 1.1 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal FAM176 PF14851.1 CDI74893.1 - 0.24 11.0 6.7 0.26 10.9 4.6 1.1 1 0 0 1 1 1 0 FAM176 family Methyltransf_32 PF13679.1 CDI74893.1 - 0.24 11.0 5.2 0.28 10.8 3.6 1.1 1 0 0 1 1 1 0 Methyltransferase domain Coiled-coil_56 PF09813.4 CDI74893.1 - 0.25 11.3 5.1 0.32 10.9 3.6 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 56 RP-C_C PF11800.3 CDI74893.1 - 0.27 10.9 6.0 0.25 10.9 4.2 1.0 1 0 0 1 1 1 0 Replication protein C C-terminal region DUF4175 PF13779.1 CDI74893.1 - 0.32 8.6 24.6 0.34 8.5 17.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Peptidase_S49_N PF08496.5 CDI74893.1 - 0.32 10.7 6.2 0.37 10.5 4.3 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Bud13 PF09736.4 CDI74893.1 - 0.33 11.2 9.9 0.31 11.2 6.9 1.1 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex TRP PF06011.7 CDI74893.1 - 0.37 9.3 1.8 0.38 9.2 1.2 1.0 1 0 0 1 1 1 0 Transient receptor potential (TRP) ion channel SpoIISA_toxin PF14171.1 CDI74893.1 - 0.39 9.9 2.6 0.46 9.7 1.8 1.0 1 0 0 1 1 1 0 Toxin SpoIISA, type II toxin-antitoxin system XRCC4 PF06632.7 CDI74893.1 - 0.43 9.3 6.3 0.45 9.3 4.4 1.0 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 PAT1 PF09770.4 CDI74893.1 - 0.44 8.7 19.4 0.43 8.7 13.5 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 PEX11 PF05648.9 CDI74893.1 - 0.48 9.6 4.7 0.51 9.5 3.2 1.1 1 0 0 1 1 1 0 Peroxisomal biogenesis factor 11 (PEX11) DUF3371 PF11851.3 CDI74893.1 - 0.55 10.9 13.0 0.6 10.8 9.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3371) PsiA PF06952.6 CDI74893.1 - 0.57 9.2 11.2 0.66 8.9 7.8 1.0 1 0 0 1 1 1 0 PsiA protein FHIPEP PF00771.15 CDI74893.1 - 0.67 8.2 5.7 0.67 8.2 4.0 1.0 1 0 0 1 1 1 0 FHIPEP family Suf PF05843.9 CDI74893.1 - 0.72 9.5 13.9 0.77 9.4 9.6 1.0 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Trypan_glycop_C PF10659.4 CDI74893.1 - 0.74 10.1 10.7 0.81 10.0 7.4 1.1 1 0 0 1 1 1 0 Trypanosome variant surface glycoprotein C-terminal domain DDHD PF02862.12 CDI74893.1 - 0.77 9.5 7.2 0.76 9.5 5.0 1.1 1 0 0 1 1 1 0 DDHD domain Ctr PF04145.10 CDI74893.1 - 0.79 9.7 4.4 0.83 9.6 3.0 1.1 1 0 0 1 1 1 0 Ctr copper transporter family FlaG PF03646.10 CDI74893.1 - 0.81 9.8 14.3 0.89 9.7 9.9 1.1 1 0 0 1 1 1 0 FlaG protein WASH-7_C PF14746.1 CDI74893.1 - 0.85 9.1 9.9 0.96 9.0 6.8 1.0 1 0 0 1 1 1 0 WASH complex subunit 7, C-terminal Pex16 PF08610.5 CDI74893.1 - 0.86 8.5 8.8 0.8 8.6 6.1 1.0 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) CagX PF03524.10 CDI74893.1 - 0.87 8.8 5.7 0.87 8.8 3.9 1.1 1 0 0 1 1 1 0 Conjugal transfer protein IncA PF04156.9 CDI74893.1 - 0.98 8.9 15.8 1.1 8.8 11.0 1.1 1 0 0 1 1 1 0 IncA protein DUF533 PF04391.7 CDI74893.1 - 1 8.6 12.0 1.2 8.4 8.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF533) Gti1_Pac2 PF09729.4 CDI74893.1 - 1.1 9.1 6.8 1.1 9.0 4.7 1.1 1 0 0 1 1 1 0 Gti1/Pac2 family Serinc PF03348.10 CDI74893.1 - 1.1 7.8 8.6 1.2 7.8 6.0 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) Med15 PF09606.5 CDI74893.1 - 1.2 7.2 30.1 1.1 7.4 20.9 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal EIIBC-GUT_N PF03612.9 CDI74893.1 - 1.2 8.7 7.4 1.3 8.6 5.1 1.1 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus eIF-3_zeta PF05091.7 CDI74893.1 - 1.2 7.6 10.1 1.2 7.6 7.0 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF3464 PF11947.3 CDI74893.1 - 1.2 8.5 6.2 1.4 8.3 4.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) DUF4557 PF15101.1 CDI74893.1 - 1.3 8.8 16.0 1.3 8.7 11.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) AIF_C PF14721.1 CDI74893.1 - 1.3 9.3 6.9 1.3 9.2 4.8 1.1 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Ycf1 PF05758.7 CDI74893.1 - 1.3 6.6 8.5 1.3 6.6 5.9 1.0 1 0 0 1 1 1 0 Ycf1 FLO_LFY PF01698.11 CDI74893.1 - 1.4 7.7 7.4 1.2 7.8 5.1 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein DDRGK PF09756.4 CDI74893.1 - 1.4 8.2 12.9 1.7 8.0 8.9 1.1 1 0 0 1 1 1 0 DDRGK domain Med13_N PF11597.3 CDI74893.1 - 1.6 7.2 10.7 1.5 7.3 7.4 1.0 1 0 0 1 1 1 0 Mediator complex subunit 13 N-terminal Paf1 PF03985.8 CDI74893.1 - 1.7 7.2 10.2 1.8 7.2 7.1 1.0 1 0 0 1 1 1 0 Paf1 Folate_carrier PF01770.13 CDI74893.1 - 1.8 6.9 7.1 1.8 6.9 4.9 1.0 1 0 0 1 1 1 0 Reduced folate carrier RR_TM4-6 PF06459.7 CDI74893.1 - 1.9 8.2 8.1 2.1 8.1 5.6 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 BAF1_ABF1 PF04684.8 CDI74893.1 - 1.9 7.2 27.0 1.8 7.3 18.7 1.0 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor DUF2126 PF09899.4 CDI74893.1 - 2 6.3 6.5 2.2 6.2 4.5 1.0 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) Baculo_PP31 PF05311.6 CDI74893.1 - 2 7.5 9.3 2.1 7.5 6.4 1.0 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) Spt20 PF12090.3 CDI74893.1 - 2 7.6 13.3 2.4 7.4 9.2 1.2 1 0 0 1 1 1 0 Spt20 family Glyco_transf_15 PF01793.11 CDI74893.1 - 2.1 7.2 7.3 2.1 7.1 5.1 1.0 1 0 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase Gag_spuma PF03276.9 CDI74893.1 - 2.2 6.4 18.7 2.2 6.5 12.9 1.0 1 0 0 1 1 1 0 Spumavirus gag protein PH_4 PF15404.1 CDI74893.1 - 2.4 7.6 8.5 2.7 7.4 5.9 1.1 1 0 0 1 1 1 0 Pleckstrin homology domain SAGA-Tad1 PF12767.2 CDI74893.1 - 2.4 7.7 12.7 2.5 7.6 8.8 1.0 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit RAB3GAP2_N PF14655.1 CDI74893.1 - 2.5 7.0 10.1 3.2 6.6 7.0 1.3 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus ATAD4 PF15321.1 CDI74893.1 - 2.8 9.0 8.9 3.1 8.8 6.2 1.2 1 0 0 1 1 1 0 ATPase family AAA domain containing 4 DHHW PF14286.1 CDI74893.1 - 3 7.0 6.3 2.9 7.1 4.4 1.0 1 0 0 1 1 1 0 DHHW protein SprA-related PF12118.3 CDI74893.1 - 3.1 7.0 25.3 3.7 6.8 17.5 1.1 1 0 0 1 1 1 0 SprA-related family Band_3_cyto PF07565.8 CDI74893.1 - 3.8 6.9 10.7 4 6.8 7.4 1.0 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Plasmodium_Vir PF05795.6 CDI74893.1 - 4 6.5 5.5 4.5 6.3 3.8 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Hid1 PF12722.2 CDI74893.1 - 4.5 4.8 9.5 4.5 4.8 6.6 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Cellulose_synt PF03552.9 CDI74893.1 - 5.6 5.1 5.9 5.2 5.2 4.1 1.0 1 0 0 1 1 1 0 Cellulose synthase DUF1980 PF09323.5 CDI74893.1 - 5.9 6.6 8.0 6.2 6.5 5.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) OmpH PF03938.9 CDI74893.1 - 6.1 6.7 24.1 7.2 6.5 16.7 1.0 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF3043 PF11241.3 CDI74893.1 - 6.4 6.3 8.1 8 6.0 5.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) G0-G1_switch_2 PF15103.1 CDI74893.1 - 6.8 6.9 9.1 8.6 6.6 6.3 1.2 1 0 0 1 1 1 0 G0/G1 switch protein 2 RED_N PF07808.8 CDI74893.1 - 7.5 5.6 15.0 7.8 5.6 10.4 1.1 1 0 0 1 1 1 0 RED-like protein N-terminal region Kei1 PF08552.6 CDI74893.1 - 7.8 6.1 7.5 7.8 6.1 5.2 1.1 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 DivIC PF04977.10 CDI74893.1 - 8.8 5.8 17.5 12 5.5 12.1 1.2 1 0 0 1 1 1 0 Septum formation initiator Chorion_2 PF03964.10 CDI74894.1 - 0.01 16.3 0.1 0.016 15.7 0.1 1.4 1 0 0 1 1 1 0 Chorion family 2 CAF-1_p150 PF11600.3 CDI74895.1 - 0.00017 21.0 49.9 0.00017 21.0 34.6 3.2 2 1 1 3 3 3 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal Med15 PF09606.5 CDI74896.1 - 0.15 10.2 68.2 0.16 10.1 47.3 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Asp-B-Hydro_N PF05279.6 CDI74896.1 - 2.9 7.6 16.6 3.2 7.5 11.5 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region eIF-3_zeta PF05091.7 CDI74896.1 - 5 5.6 25.4 5.9 5.3 17.6 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) PAT1 PF09770.4 CDI74896.1 - 5.2 5.1 64.2 6.4 4.8 44.5 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Macoilin PF09726.4 CDI74896.1 - 5.4 5.1 38.7 7.5 4.7 26.8 1.2 1 0 0 1 1 1 0 Transmembrane protein Dicty_REP PF05086.7 CDI74896.1 - 7.3 4.2 24.4 9.2 3.8 16.9 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Tcf25 PF04910.9 CDI74897.1 - 0.037 12.9 0.1 0.05 12.5 0.0 1.2 1 1 0 1 1 1 0 Transcriptional repressor TCF25 Corona_nucleoca PF00937.13 CDI74897.1 - 0.47 9.3 4.4 0.24 10.3 1.3 1.7 2 0 0 2 2 2 0 Coronavirus nucleocapsid protein Syntaphilin PF15290.1 CDI74897.1 - 5.3 6.4 8.1 9.2 5.6 5.6 1.3 1 0 0 1 1 1 0 Golgi-localised syntaxin-1-binding clamp PAT1 PF09770.4 CDI74898.1 - 3.7 5.6 79.9 1.3 7.2 45.4 2.3 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 Qn_am_d_aIII PF09099.5 CDI74899.1 - 0.097 12.9 0.0 0.23 11.7 0.0 1.6 1 0 0 1 1 1 0 Quinohemoprotein amine dehydrogenase, alpha subunit domain III DNA_pol3_delta2 PF13177.1 CDI74900.1 - 3.8e-15 55.9 0.0 6e-14 52.0 0.0 2.5 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.24 CDI74900.1 - 1.4e-14 54.4 0.0 2.7e-14 53.4 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.10 CDI74900.1 - 3.2e-08 32.6 0.0 0.0013 17.5 0.0 2.1 2 0 0 2 2 2 2 Rad17 cell cycle checkpoint protein AAA_22 PF13401.1 CDI74900.1 - 5.2e-07 29.8 0.0 2.3e-06 27.7 0.0 2.1 2 2 0 2 2 2 1 AAA domain AAA_14 PF13173.1 CDI74900.1 - 3.1e-05 23.8 0.0 5.6e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.8 CDI74900.1 - 3.2e-05 22.8 0.0 0.0032 16.2 0.0 2.2 2 0 0 2 2 2 1 TIP49 C-terminus AAA_16 PF13191.1 CDI74900.1 - 7.4e-05 22.8 1.7 0.00038 20.4 0.0 2.5 2 1 0 2 2 2 1 AAA ATPase domain RuvB_N PF05496.7 CDI74900.1 - 8.9e-05 21.6 0.0 0.00055 19.0 0.0 2.0 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_10 PF12846.2 CDI74900.1 - 0.00011 21.7 0.1 0.00073 19.0 0.1 2.3 1 1 0 1 1 1 1 AAA-like domain DUF2075 PF09848.4 CDI74900.1 - 0.00014 20.9 0.0 0.0002 20.4 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) FtsK_SpoIIIE PF01580.13 CDI74900.1 - 0.00015 21.2 0.3 0.001 18.5 0.0 2.4 2 1 1 3 3 3 1 FtsK/SpoIIIE family Rep_fac_C PF08542.6 CDI74900.1 - 0.00024 21.0 0.4 0.00079 19.3 0.2 2.0 1 1 0 1 1 1 1 Replication factor C C-terminal domain AAA_19 PF13245.1 CDI74900.1 - 0.00038 20.1 0.3 0.0011 18.6 0.0 2.0 2 0 0 2 2 1 1 Part of AAA domain KTI12 PF08433.5 CDI74900.1 - 0.0004 19.6 0.0 0.00072 18.8 0.0 1.4 1 0 0 1 1 1 1 Chromatin associated protein KTI12 Mg_chelatase PF01078.16 CDI74900.1 - 0.00047 19.3 0.2 0.0024 17.0 0.0 2.2 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_30 PF13604.1 CDI74900.1 - 0.00052 19.6 0.0 0.0014 18.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 CDI74900.1 - 0.00087 19.0 0.1 0.0044 16.7 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) ArgK PF03308.11 CDI74900.1 - 0.0012 17.6 2.5 0.11 11.2 0.0 2.9 2 1 1 3 3 3 1 ArgK protein AAA_25 PF13481.1 CDI74900.1 - 0.0021 17.4 0.1 0.0063 15.9 0.1 1.9 1 1 0 1 1 1 1 AAA domain DEAD PF00270.24 CDI74900.1 - 0.003 17.0 0.0 0.63 9.5 0.0 2.4 1 1 0 2 2 2 1 DEAD/DEAH box helicase AAA_17 PF13207.1 CDI74900.1 - 0.004 17.9 0.0 0.011 16.5 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_11 PF13086.1 CDI74900.1 - 0.0048 16.4 0.0 0.0085 15.6 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 CDI74900.1 - 0.0071 16.6 0.0 0.014 15.6 0.0 1.7 1 1 0 1 1 1 1 AAA domain Zot PF05707.7 CDI74900.1 - 0.0077 15.7 0.0 0.015 14.7 0.0 1.4 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) Arch_ATPase PF01637.13 CDI74900.1 - 0.01 15.5 0.0 0.017 14.8 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase DUF1118 PF06549.7 CDI74900.1 - 0.01 15.9 2.0 0.032 14.3 1.4 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1118) AAA_33 PF13671.1 CDI74900.1 - 0.012 15.5 0.1 0.028 14.2 0.1 1.7 1 1 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 CDI74900.1 - 0.014 14.7 0.0 0.1 11.9 0.0 2.2 1 1 0 1 1 1 0 IstB-like ATP binding protein AAA_28 PF13521.1 CDI74900.1 - 0.015 15.2 0.0 0.033 14.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_2 PF07724.9 CDI74900.1 - 0.03 14.2 0.0 0.1 12.5 0.0 1.8 2 1 0 2 2 2 0 AAA domain (Cdc48 subfamily) Sigma54_activ_2 PF14532.1 CDI74900.1 - 0.032 14.2 0.0 4.9 7.1 0.0 2.9 3 0 0 3 3 3 0 Sigma-54 interaction domain AAA_24 PF13479.1 CDI74900.1 - 0.057 13.0 0.0 0.12 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain SNF2_N PF00176.18 CDI74900.1 - 0.064 12.0 0.0 0.77 8.4 0.0 2.1 1 1 0 2 2 2 0 SNF2 family N-terminal domain ResIII PF04851.10 CDI74900.1 - 0.086 12.6 0.0 0.17 11.7 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Activator_LAG-3 PF11498.3 CDI74903.1 - 0.0012 17.7 30.2 0.0012 17.7 21.0 2.1 2 0 0 2 2 2 1 Transcriptional activator LAG-3 PRP1_N PF06424.7 CDI74904.1 - 3.7 7.8 14.9 11 6.3 10.4 1.8 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal ECH_C PF13766.1 CDI74905.1 - 6.2e-17 61.8 13.0 5.5e-10 39.4 0.4 3.8 3 1 1 4 4 4 2 2-enoyl-CoA Hydratase C-terminal region ECH PF00378.15 CDI74905.1 - 1.5e-11 43.8 0.0 1.5e-11 43.8 0.0 3.5 3 1 1 4 4 4 1 Enoyl-CoA hydratase/isomerase family SAPS PF04499.10 CDI74905.1 - 0.0039 15.8 8.4 0.0077 14.9 0.2 2.1 2 0 0 2 2 2 2 SIT4 phosphatase-associated protein SPX PF03105.14 CDI74905.1 - 0.005 16.6 13.3 0.04 13.7 5.4 2.1 2 0 0 2 2 2 2 SPX domain Pol_alpha_B_N PF08418.5 CDI74905.1 - 0.01 15.3 18.1 0.025 14.1 7.4 2.3 2 0 0 2 2 2 0 DNA polymerase alpha subunit B N-terminal Med15 PF09606.5 CDI74905.1 - 0.066 11.4 53.1 0.11 10.6 15.4 2.2 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF4175 PF13779.1 CDI74905.1 - 0.48 8.0 36.5 1 6.9 7.8 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4175) HlyD_2 PF12700.2 CDI74905.1 - 0.83 8.7 10.5 0.15 11.1 1.4 2.1 2 0 0 2 2 2 0 HlyD family secretion protein TFIIA PF03153.8 CDI74905.1 - 0.95 9.2 35.8 0.6 9.9 7.9 2.3 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Ndc1_Nup PF09531.5 CDI74905.1 - 8.3 4.7 21.1 3.7 5.8 10.3 2.1 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup PDGF_N PF04692.8 CDI74906.1 - 0.0021 18.5 5.3 0.0021 18.5 3.7 3.2 2 1 1 3 3 3 1 Platelet-derived growth factor, N terminal region WD40 PF00400.27 CDI74906.1 - 0.0037 17.0 0.9 0.015 15.1 0.1 2.4 2 0 0 2 2 2 1 WD domain, G-beta repeat Utp14 PF04615.8 CDI74906.1 - 0.54 8.3 21.1 0.61 8.1 14.6 1.1 1 0 0 1 1 1 0 Utp14 protein Peptidase_S64 PF08192.6 CDI74906.1 - 1.5 7.0 26.4 1.8 6.8 18.3 1.3 1 0 0 1 1 1 0 Peptidase family S64 DUF605 PF04652.11 CDI74906.1 - 1.7 7.9 32.3 2.4 7.4 22.4 1.2 1 0 0 1 1 1 0 Vta1 like FAM196 PF15265.1 CDI74906.1 - 2.6 7.1 35.8 3.3 6.8 24.8 1.1 1 0 0 1 1 1 0 FAM196 family Hid1 PF12722.2 CDI74906.1 - 2.6 5.5 21.4 3.7 5.1 14.8 1.3 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Ebola_NP PF05505.7 CDI74906.1 - 6.1 4.7 14.0 7.5 4.4 9.7 1.1 1 0 0 1 1 1 0 Ebola nucleoprotein DUF3801 PF12687.2 CDI74910.1 - 0.022 14.3 18.5 0.027 14.0 12.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3801) RAP1 PF07218.6 CDI74910.1 - 6.9 4.6 7.9 7 4.6 5.5 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) CAF-1_p150 PF11600.3 CDI74910.1 - 9.3 5.5 34.8 1.2 8.4 11.5 2.1 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF2217 PF10265.4 CDI74910.1 - 9.7 4.8 22.7 11 4.6 15.8 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) CagX PF03524.10 CDI74910.1 - 9.9 5.3 17.3 1.7 7.8 4.5 2.0 2 0 0 2 2 2 0 Conjugal transfer protein PH_BEACH PF14844.1 CDI74911.1 - 0.56 10.0 10.5 0.017 14.9 2.2 2.4 2 0 0 2 2 2 0 PH domain associated with Beige/BEACH TFIIA PF03153.8 CDI74914.1 - 0.095 12.5 8.2 0.16 11.8 5.7 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Pex14_N PF04695.8 CDI74914.1 - 0.12 12.3 4.8 0.23 11.4 3.3 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Suf PF05843.9 CDI74914.1 - 0.45 10.2 3.5 0.8 9.3 2.4 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Neisseria_TspB PF05616.8 CDI74914.1 - 1.3 7.3 3.5 2.1 6.6 2.4 1.2 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein DUF3369 PF11849.3 CDI74914.1 - 1.3 8.8 4.7 8.9 6.2 1.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3369) SART-1 PF03343.8 CDI74915.1 - 0.083 11.2 18.2 0.088 11.1 12.6 1.0 1 0 0 1 1 1 0 SART-1 family DUF106 PF01956.11 CDI74915.1 - 0.098 12.1 6.8 0.11 11.9 4.7 1.1 1 0 0 1 1 1 0 Integral membrane protein DUF106 FLO_LFY PF01698.11 CDI74915.1 - 1.3 7.8 12.6 1.6 7.4 8.7 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein PRCH PF03967.8 CDI74915.1 - 1.3 8.5 4.1 1.6 8.3 2.9 1.3 1 0 0 1 1 1 0 Photosynthetic reaction centre, H-chain N-terminal region GAGA_bind PF06217.7 CDI74915.1 - 1.5 8.7 12.7 1.5 8.7 8.8 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family CPSF73-100_C PF11718.3 CDI74915.1 - 1.5 8.1 5.1 1.7 7.9 3.6 1.1 1 0 0 1 1 1 0 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term YL1 PF05764.8 CDI74915.1 - 1.5 8.3 19.9 1.8 8.1 13.8 1.2 1 0 0 1 1 1 0 YL1 nuclear protein SAGA-Tad1 PF12767.2 CDI74915.1 - 2 8.0 9.5 2.2 7.9 6.6 1.1 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit TP53IP5 PF15331.1 CDI74915.1 - 4.6 7.1 14.5 4.9 6.9 10.0 1.2 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 RabGAP-TBC PF00566.13 CDI74915.1 - 5.3 6.4 6.7 6.3 6.2 4.6 1.1 1 0 0 1 1 1 0 Rab-GTPase-TBC domain Peptidase_S49_N PF08496.5 CDI74915.1 - 5.3 6.8 15.0 6.8 6.4 10.4 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal AAA_13 PF13166.1 CDI74915.1 - 5.4 5.3 13.2 5.5 5.3 9.1 1.0 1 0 0 1 1 1 0 AAA domain SR-25 PF10500.4 CDI74917.1 - 0.031 13.7 38.7 0.52 9.7 13.1 2.1 1 1 1 2 2 2 0 Nuclear RNA-splicing-associated protein PAT1 PF09770.4 CDI74917.1 - 2.2 6.4 58.8 2.5 6.2 40.7 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TFIIA PF03153.8 CDI74917.1 - 2.5 7.8 46.1 3.7 7.3 32.0 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Oleosin PF01277.12 CDI74917.1 - 4.1 7.0 16.3 0.17 11.4 1.5 2.5 2 1 1 3 3 3 0 Oleosin DDHD PF02862.12 CDI74918.1 - 0.14 11.9 9.2 0.17 11.6 6.4 1.1 1 0 0 1 1 1 0 DDHD domain GDE_N PF12439.3 CDI74918.1 - 0.22 10.7 10.1 0.24 10.5 7.0 1.1 1 0 0 1 1 1 0 Glycogen debranching enzyme N terminal Syja_N PF02383.13 CDI74918.1 - 0.32 9.7 10.0 0.37 9.5 6.9 1.1 1 0 0 1 1 1 0 SacI homology domain 2OG-FeII_Oxy_5 PF13759.1 CDI74918.1 - 0.79 10.0 8.1 0.23 11.7 2.8 1.9 1 1 1 2 2 2 0 Putative 2OG-Fe(II) oxygenase LAM_C PF12544.3 CDI74918.1 - 1 9.4 7.6 1.4 9.0 5.3 1.3 1 0 0 1 1 1 0 Lysine-2,3-aminomutase Herpes_DNAp_acc PF04929.7 CDI74918.1 - 1.3 7.9 7.5 1.2 8.0 5.2 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor DUF4512 PF14975.1 CDI74918.1 - 1.4 9.7 5.5 2.2 9.1 3.8 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4512) Baculo_PP31 PF05311.6 CDI74918.1 - 1.6 7.9 10.4 2.1 7.5 7.2 1.2 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) Rer1 PF03248.8 CDI74918.1 - 2.6 7.5 7.0 0.45 10.0 0.2 2.1 2 0 0 2 2 2 0 Rer1 family FAM163 PF15069.1 CDI74918.1 - 2.7 8.5 5.1 3.6 8.1 3.5 1.3 1 0 0 1 1 1 0 FAM163 family PAT1 PF09770.4 CDI74918.1 - 3.6 5.7 40.6 4 5.5 28.1 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 eIF-3_zeta PF05091.7 CDI74918.1 - 3.7 6.0 19.1 4.3 5.8 13.2 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) BTV_NS2 PF04514.7 CDI74918.1 - 4.8 5.9 13.6 5.5 5.7 9.4 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Hid1 PF12722.2 CDI74918.1 - 7.8 4.0 15.9 8.2 3.9 11.0 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein IncA PF04156.9 CDI74919.1 - 0.0018 17.9 2.9 0.0018 17.9 2.0 3.0 1 1 2 3 3 1 1 IncA protein DUF4604 PF15377.1 CDI74919.1 - 0.0019 18.4 24.9 0.0025 18.0 17.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4604) GAGA_bind PF06217.7 CDI74919.1 - 0.0019 18.1 10.4 0.0022 18.0 7.2 1.1 1 0 0 1 1 1 1 GAGA binding protein-like family FLO_LFY PF01698.11 CDI74919.1 - 0.0024 16.8 5.5 0.0029 16.5 3.8 1.1 1 0 0 1 1 1 1 Floricaula / Leafy protein DDHD PF02862.12 CDI74919.1 - 0.0052 16.6 6.0 0.0065 16.2 4.2 1.2 1 0 0 1 1 1 1 DDHD domain Serinc PF03348.10 CDI74919.1 - 0.0088 14.7 3.4 0.012 14.4 2.4 1.1 1 0 0 1 1 1 1 Serine incorporator (Serinc) DUF1510 PF07423.6 CDI74919.1 - 0.012 15.0 15.1 0.016 14.5 10.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) U79_P34 PF03064.11 CDI74919.1 - 0.014 14.9 11.3 0.019 14.4 7.8 1.2 1 0 0 1 1 1 0 HSV U79 / HCMV P34 PBP_sp32 PF07222.7 CDI74919.1 - 0.021 14.0 8.2 0.029 13.5 5.7 1.3 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Pex24p PF06398.6 CDI74919.1 - 0.04 12.6 1.8 0.048 12.4 1.2 1.1 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin DUF3807 PF12720.2 CDI74919.1 - 0.055 13.6 12.5 0.076 13.1 8.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) RNase_H2-Ydr279 PF09468.5 CDI74919.1 - 0.068 12.3 20.4 0.095 11.8 14.1 1.3 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) RPOL_N PF14700.1 CDI74919.1 - 0.072 12.3 12.5 0.09 12.0 8.7 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase N-terminal Vfa1 PF08432.5 CDI74919.1 - 0.08 12.9 26.0 0.12 12.4 18.0 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Band_3_cyto PF07565.8 CDI74919.1 - 0.1 12.0 4.3 0.14 11.6 3.0 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain FemAB PF02388.11 CDI74919.1 - 0.1 11.2 15.3 0.17 10.5 10.6 1.3 1 0 0 1 1 1 0 FemAB family Paramyxo_ncap PF00973.14 CDI74919.1 - 0.12 11.0 4.8 0.15 10.7 3.4 1.2 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein RNA_pol_Rpc4 PF05132.9 CDI74919.1 - 0.14 12.1 10.5 0.21 11.5 7.3 1.2 1 0 0 1 1 1 0 RNA polymerase III RPC4 HSNSD PF12062.3 CDI74919.1 - 0.15 10.4 2.7 0.19 10.1 1.8 1.1 1 0 0 1 1 1 0 heparan sulfate-N-deacetylase Peptidase_S49_N PF08496.5 CDI74919.1 - 0.16 11.7 27.7 0.084 12.6 17.7 1.6 1 1 1 2 2 2 0 Peptidase family S49 N-terminal Misat_Tub_SegII PF10644.4 CDI74919.1 - 0.23 11.5 5.0 0.36 10.9 3.5 1.2 1 0 0 1 1 1 0 Misato Segment II tubulin-like domain RR_TM4-6 PF06459.7 CDI74919.1 - 0.33 10.8 16.9 0.44 10.3 11.7 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Neur_chan_memb PF02932.11 CDI74919.1 - 0.36 10.6 2.9 0.48 10.2 2.0 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region OATP PF03137.15 CDI74919.1 - 0.36 8.8 6.3 0.66 7.9 4.4 1.4 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family TATR PF03430.8 CDI74919.1 - 0.44 9.1 12.8 0.54 8.8 8.9 1.1 1 0 0 1 1 1 0 Trans-activating transcriptional regulator Ycf1 PF05758.7 CDI74919.1 - 0.46 8.1 13.5 0.58 7.8 9.3 1.0 1 0 0 1 1 1 0 Ycf1 DDRGK PF09756.4 CDI74919.1 - 0.46 9.8 26.3 0.62 9.4 18.2 1.1 1 0 0 1 1 1 0 DDRGK domain Raftlin PF15250.1 CDI74919.1 - 0.51 8.7 15.6 0.67 8.4 10.8 1.1 1 0 0 1 1 1 0 Raftlin DUF913 PF06025.7 CDI74919.1 - 0.55 8.9 2.9 0.7 8.5 2.0 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) NPR3 PF03666.8 CDI74919.1 - 0.59 8.6 13.7 0.77 8.2 9.5 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Dala_Dala_lig_N PF01820.16 CDI74919.1 - 0.68 10.2 4.5 1.1 9.5 3.1 1.4 1 0 0 1 1 1 0 D-ala D-ala ligase N-terminus Anoctamin PF04547.7 CDI74919.1 - 0.69 8.5 5.0 1.2 7.7 3.5 1.3 1 0 0 1 1 1 0 Calcium-activated chloride channel Rot1 PF10681.4 CDI74919.1 - 1.1 8.5 4.9 1.7 7.9 3.4 1.2 1 0 0 1 1 1 0 Chaperone for protein-folding within the ER, fungal RNA_pol_Rpb1_5 PF04998.12 CDI74919.1 - 1.2 8.3 10.2 1.6 7.9 7.1 1.1 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 Rtf2 PF04641.7 CDI74919.1 - 2 7.5 23.7 3.3 6.8 16.5 1.3 1 0 0 1 1 1 0 Rtf2 RING-finger SHR3_chaperone PF08229.6 CDI74919.1 - 2.6 6.9 14.5 4.2 6.2 10.1 1.3 1 0 0 1 1 1 0 ER membrane protein SH3 Glyco_transf_15 PF01793.11 CDI74919.1 - 2.7 6.8 11.0 3.6 6.4 7.6 1.1 1 0 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase LicD PF04991.8 CDI74919.1 - 3.1 7.8 12.3 3.9 7.5 8.5 1.1 1 0 0 1 1 1 0 LicD family Arc_PepC_II PF06847.6 CDI74919.1 - 3.2 8.2 8.7 5.2 7.5 6.0 1.3 1 0 0 1 1 1 0 Archaeal Peptidase A24 C-terminus Type II Auxin_inducible PF02519.9 CDI74919.1 - 3.2 7.8 9.8 6.3 6.9 6.8 1.5 1 0 0 1 1 1 0 Auxin responsive protein Fmp27 PF10344.4 CDI74919.1 - 3.9 5.0 13.2 4.7 4.7 9.2 1.0 1 0 0 1 1 1 0 Mitochondrial protein from FMP27 Peptidase_U57 PF05582.7 CDI74919.1 - 6.3 5.6 12.2 8.7 5.2 8.5 1.1 1 0 0 1 1 1 0 YabG peptidase U57 Cellulose_synt PF03552.9 CDI74919.1 - 7.6 4.6 8.8 10 4.2 6.1 1.1 1 0 0 1 1 1 0 Cellulose synthase DAGK_prokar PF01219.14 CDI74920.1 - 0.082 12.4 0.1 0.082 12.4 0.1 2.1 1 1 1 2 2 2 0 Prokaryotic diacylglycerol kinase DUF3138 PF11336.3 CDI74920.1 - 0.084 11.0 5.2 0.1 10.7 3.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) CW_binding_2 PF04122.7 CDI74920.1 - 0.92 9.7 4.6 2 8.6 0.0 2.1 2 0 0 2 2 2 0 Putative cell wall binding repeat 2 RR_TM4-6 PF06459.7 CDI74921.1 - 0.012 15.5 9.1 0.015 15.2 6.3 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 TEX19 PF15553.1 CDI74921.1 - 0.023 14.5 1.8 0.029 14.2 1.3 1.1 1 0 0 1 1 1 0 Testis-expressed protein 19 Pex14_N PF04695.8 CDI74921.1 - 0.087 12.8 9.7 0.11 12.5 6.7 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region CDC45 PF02724.9 CDI74921.1 - 0.13 10.2 13.4 0.16 9.9 9.3 1.1 1 0 0 1 1 1 0 CDC45-like protein Spore_YhcN_YlaJ PF09580.5 CDI74921.1 - 0.19 11.8 9.9 0.26 11.3 6.9 1.2 1 0 0 1 1 1 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) RP-C_C PF11800.3 CDI74921.1 - 0.37 10.4 8.3 0.51 10.0 5.8 1.2 1 0 0 1 1 1 0 Replication protein C C-terminal region DUF4175 PF13779.1 CDI74921.1 - 0.4 8.3 23.3 0.47 8.0 16.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Suf PF05843.9 CDI74921.1 - 0.41 10.3 7.8 0.51 10.0 5.4 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) PBP1_TM PF14812.1 CDI74921.1 - 0.44 10.8 10.3 0.96 9.8 7.2 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal SprA-related PF12118.3 CDI74921.1 - 0.48 9.7 24.2 0.64 9.3 16.8 1.1 1 0 0 1 1 1 0 SprA-related family DUF1510 PF07423.6 CDI74921.1 - 0.49 9.7 16.0 0.61 9.4 11.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) FimP PF09766.4 CDI74921.1 - 0.57 9.1 16.5 0.73 8.8 11.5 1.2 1 0 0 1 1 1 0 Fms-interacting protein FAM176 PF14851.1 CDI74921.1 - 1.1 8.9 6.1 1.5 8.4 4.2 1.2 1 0 0 1 1 1 0 FAM176 family DUF2228 PF10228.4 CDI74921.1 - 1.1 8.7 7.0 1.6 8.2 4.6 1.3 1 1 0 1 1 1 0 Uncharacterised conserved protein (DUF2228) DDHD PF02862.12 CDI74921.1 - 1.4 8.7 9.6 1.8 8.3 6.7 1.1 1 0 0 1 1 1 0 DDHD domain Presenilin PF01080.12 CDI74921.1 - 2.9 6.6 7.1 3.2 6.4 5.0 1.1 1 0 0 1 1 1 0 Presenilin Sec62 PF03839.11 CDI74921.1 - 3.3 7.0 8.7 4.1 6.7 6.0 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 DUF2058 PF09831.4 CDI74921.1 - 5.7 6.7 21.5 7.7 6.3 14.9 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2058) Folate_carrier PF01770.13 CDI74921.1 - 7.7 4.9 6.0 9.8 4.5 4.2 1.1 1 0 0 1 1 1 0 Reduced folate carrier Ycf1 PF05758.7 CDI74921.1 - 8.1 4.0 12.4 9.2 3.8 8.6 1.0 1 0 0 1 1 1 0 Ycf1 Kei1 PF08552.6 CDI74921.1 - 8.6 5.9 5.9 11 5.6 4.1 1.2 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 CDK2AP PF09806.4 CDI74922.1 - 0.13 12.4 3.9 0.22 11.7 2.7 1.4 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein NARP1 PF12569.3 CDI74922.1 - 0.58 8.8 5.0 0.77 8.4 3.5 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 GAGA_bind PF06217.7 CDI74922.1 - 2.1 8.2 7.3 2.6 7.9 5.0 1.4 1 1 0 1 1 1 0 GAGA binding protein-like family CAF-1_p150 PF11600.3 CDI74923.1 - 2.2 7.6 58.6 2.7 7.3 40.6 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Utp14 PF04615.8 CDI74923.1 - 2.6 6.1 55.0 2.9 5.9 38.1 1.0 1 0 0 1 1 1 0 Utp14 protein DUF605 PF04652.11 CDI74925.1 - 0.034 13.5 27.0 0.045 13.1 18.7 1.1 1 0 0 1 1 1 0 Vta1 like DUF4175 PF13779.1 CDI74925.1 - 1 6.9 17.0 1.4 6.4 11.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) tRNA_synt_1c_R2 PF04557.10 CDI74925.1 - 2.3 8.9 5.5 17 6.1 1.6 2.7 2 1 0 2 2 2 0 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 FimP PF09766.4 CDI74925.1 - 6.4 5.7 16.9 0.33 9.9 6.4 1.9 2 0 0 2 2 2 0 Fms-interacting protein DUF2052 PF09747.4 CDI74925.1 - 7.1 6.5 15.5 1.2 9.0 4.8 2.1 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) DUF4557 PF15101.1 CDI74925.1 - 7.1 6.4 13.9 0.31 10.8 4.9 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4557) DUF1510 PF07423.6 CDI74925.1 - 8.9 5.6 17.7 6 6.1 2.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) DUF1042 PF06294.6 CDI74926.1 - 0.034 13.7 3.1 0.052 13.1 2.1 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1042) SLD3 PF08639.5 CDI74926.1 - 0.24 9.9 13.2 0.34 9.5 9.2 1.1 1 0 0 1 1 1 0 DNA replication regulator SLD3 BAF1_ABF1 PF04684.8 CDI74926.1 - 0.24 10.1 10.8 0.31 9.8 7.5 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Macoilin PF09726.4 CDI74926.1 - 0.3 9.3 5.9 0.39 8.9 4.1 1.1 1 0 0 1 1 1 0 Transmembrane protein CDK2AP PF09806.4 CDI74926.1 - 0.58 10.3 9.9 1.1 9.4 6.9 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein DNA_pol_viral_N PF00242.12 CDI74926.1 - 0.72 8.8 12.4 0.97 8.3 8.6 1.1 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain Hid1 PF12722.2 CDI74926.1 - 3.4 5.2 9.1 4.3 4.8 6.3 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF4175 PF13779.1 CDI74926.1 - 3.7 5.1 15.7 4.9 4.7 10.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) MDFI PF15316.1 CDI74926.1 - 5.3 7.0 4.9 7.7 6.4 3.4 1.3 1 0 0 1 1 1 0 MyoD family inhibitor Folliculin PF11704.3 CDI74926.1 - 9.6 5.7 8.7 44 3.5 6.1 1.9 1 1 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport FimP PF09766.4 CDI74929.1 - 9.2e-06 24.9 5.9 1.1e-05 24.6 4.1 1.1 1 0 0 1 1 1 1 Fms-interacting protein Fig1 PF12351.3 CDI74929.1 - 0.00038 20.3 5.1 0.00038 20.3 3.5 1.6 2 0 0 2 2 1 1 Ca2+ regulator and membrane fusion protein Fig1 AIF_C PF14721.1 CDI74929.1 - 0.0014 18.8 0.6 0.0022 18.2 0.4 1.4 1 0 0 1 1 1 1 Apoptosis-inducing factor, mitochondrion-associated, C-term Ctr PF04145.10 CDI74929.1 - 0.0094 16.0 2.8 0.026 14.5 1.9 1.8 1 0 0 1 1 1 1 Ctr copper transporter family Kei1 PF08552.6 CDI74929.1 - 0.011 15.4 3.6 0.023 14.3 2.5 1.6 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 SUR7 PF06687.7 CDI74929.1 - 0.013 15.0 0.7 0.013 15.0 0.5 1.5 2 0 0 2 2 1 0 SUR7/PalI family Ycf1 PF05758.7 CDI74929.1 - 0.014 13.1 2.8 0.016 12.9 1.9 1.0 1 0 0 1 1 1 0 Ycf1 RR_TM4-6 PF06459.7 CDI74929.1 - 0.017 15.0 3.4 0.022 14.6 2.3 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF106 PF01956.11 CDI74929.1 - 0.033 13.7 10.2 0.052 13.0 7.1 1.5 1 1 0 1 1 1 0 Integral membrane protein DUF106 FCP1_C PF09309.5 CDI74929.1 - 0.05 12.9 8.4 0.069 12.4 5.8 1.2 1 0 0 1 1 1 0 FCP1, C-terminal PBP1_TM PF14812.1 CDI74929.1 - 0.1 12.9 0.7 0.15 12.3 0.5 1.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal EIIBC-GUT_N PF03612.9 CDI74929.1 - 0.24 11.0 9.1 0.52 9.9 6.3 1.5 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus SeqA PF03925.8 CDI74929.1 - 0.28 10.8 8.9 0.41 10.3 6.1 1.2 1 0 0 1 1 1 0 SeqA protein DUF3043 PF11241.3 CDI74929.1 - 0.36 10.3 10.5 0.056 13.0 4.4 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3043) Suf PF05843.9 CDI74929.1 - 0.59 9.8 11.0 0.75 9.4 7.6 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) CPSF100_C PF13299.1 CDI74929.1 - 0.66 10.1 7.5 0.99 9.5 5.2 1.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Pex14_N PF04695.8 CDI74929.1 - 0.75 9.8 18.9 1.5 8.8 13.1 1.5 1 1 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Peptidase_U57 PF05582.7 CDI74929.1 - 0.78 8.6 8.4 1.2 8.0 5.8 1.2 1 0 0 1 1 1 0 YabG peptidase U57 Colicin PF01024.14 CDI74929.1 - 0.97 8.9 12.9 2.2 7.8 8.9 1.5 1 0 0 1 1 1 0 Colicin pore forming domain EMP24_GP25L PF01105.19 CDI74929.1 - 1.7 8.2 12.3 1.9 8.1 8.0 1.5 1 1 0 1 1 1 0 emp24/gp25L/p24 family/GOLD CRF1 PF10380.4 CDI74929.1 - 2.3 8.5 6.4 3.1 8.1 4.5 1.2 1 0 0 1 1 1 0 Transcription factor CRF1 DUF4557 PF15101.1 CDI74929.1 - 2.6 7.8 20.3 4 7.2 14.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) Endonuc_Holl PF10107.4 CDI74929.1 - 3.2 7.4 12.2 4.9 6.8 8.5 1.2 1 0 0 1 1 1 0 Endonuclease related to archaeal Holliday junction resolvase DUF3464 PF11947.3 CDI74929.1 - 3.7 7.0 10.6 1.5 8.2 5.4 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3464) Med15 PF09606.5 CDI74929.1 - 3.8 5.5 42.4 6.2 4.8 29.4 1.3 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal RED_N PF07808.8 CDI74929.1 - 5.1 6.2 17.5 7.4 5.7 12.1 1.2 1 0 0 1 1 1 0 RED-like protein N-terminal region PAT1 PF09770.4 CDI74929.1 - 5.8 5.0 30.0 6.6 4.8 20.8 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Gag_spuma PF03276.9 CDI74929.1 - 7.5 4.7 20.8 10 4.3 14.4 1.1 1 0 0 1 1 1 0 Spumavirus gag protein UPF0560 PF10577.4 CDI74929.1 - 7.8 4.6 20.5 10 4.2 14.2 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 SR-25 PF10500.4 CDI74930.1 - 0.00055 19.4 28.3 0.0006 19.3 19.6 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein FMN_dh PF01070.13 CDI74930.1 - 2.5 6.8 16.0 3.2 6.5 11.1 1.1 1 0 0 1 1 1 0 FMN-dependent dehydrogenase Suf PF05843.9 CDI74930.1 - 3.1 7.4 42.3 4.5 6.9 29.3 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Herpes_DNAp_acc PF04929.7 CDI74930.1 - 3.8 6.3 30.3 4.4 6.1 21.0 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor PMSI1 PF15322.1 CDI74930.1 - 4.2 6.3 27.2 5.8 5.9 18.9 1.2 1 0 0 1 1 1 0 Protein missing in infertile sperm 1, putative GAGA_bind PF06217.7 CDI74930.1 - 4.4 7.1 34.7 4.7 7.0 24.0 1.0 1 0 0 1 1 1 0 GAGA binding protein-like family FAM60A PF15396.1 CDI74930.1 - 7.9 6.1 31.0 9.2 5.9 21.5 1.1 1 0 0 1 1 1 0 Protein Family FAM60A FLO_LFY PF01698.11 CDI74930.1 - 9.8 4.9 32.3 12 4.6 22.4 1.2 1 0 0 1 1 1 0 Floricaula / Leafy protein DUF4207 PF13904.1 CDI74932.1 - 0.011 15.1 31.9 0.19 11.0 7.2 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4207) HemX PF04375.9 CDI74932.1 - 0.011 14.3 1.4 0.011 14.3 1.0 2.1 1 1 1 2 2 1 0 HemX APC_CDC26 PF10471.4 CDI74932.1 - 0.016 15.9 38.7 0.29 11.8 5.3 3.6 3 0 0 3 3 3 0 Anaphase-promoting complex APC subunit 1 N6_N4_Mtase PF01555.13 CDI74932.1 - 0.05 13.0 0.0 0.11 11.9 0.0 1.6 1 1 0 1 1 1 0 DNA methylase GPCR_chapero_1 PF11904.3 CDI74932.1 - 0.067 12.3 8.0 0.016 14.3 3.5 1.4 2 0 0 2 2 2 0 GPCR-chaperone Ycf1 PF05758.7 CDI74932.1 - 0.12 10.0 6.6 0.14 9.7 4.6 1.1 1 0 0 1 1 1 0 Ycf1 Plasmodium_Vir PF05795.6 CDI74932.1 - 0.17 11.0 2.1 0.23 10.5 1.5 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein SOBP PF15279.1 CDI74932.1 - 0.26 11.6 20.2 0.35 11.2 14.0 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein DUF1180 PF06679.7 CDI74932.1 - 0.89 9.4 8.5 2.3 8.1 5.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Hid1 PF12722.2 CDI74932.1 - 1.1 6.8 13.9 1.1 6.8 9.6 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein eIF-3_zeta PF05091.7 CDI74932.1 - 1.3 7.5 14.9 2 6.9 10.3 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) NYN_YacP PF05991.6 CDI74932.1 - 1.5 8.5 10.7 0.99 9.1 1.6 2.4 2 0 0 2 2 2 0 YacP-like NYN domain G-7-MTase PF12803.2 CDI74932.1 - 1.8 7.6 5.7 2.8 7.0 4.0 1.3 1 0 0 1 1 1 0 mRNA (guanine-7-)methyltransferase (G-7-MTase) Oleosin PF01277.12 CDI74932.1 - 5.6 6.5 9.1 13 5.3 0.2 3.0 3 0 0 3 3 3 0 Oleosin DUF45 PF01863.12 CDI74932.1 - 6.5 6.4 12.0 12 5.6 8.3 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF45 Med15 PF09606.5 CDI74932.1 - 6.9 4.7 66.3 8.6 4.4 46.0 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF2077 PF09850.4 CDI74932.1 - 8.6 5.7 13.6 1.3 8.3 0.3 2.8 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2077) BRF1 PF07741.8 CDI74932.1 - 9 6.5 24.1 5.9 7.1 4.6 3.1 3 0 0 3 3 3 0 Brf1-like TBP-binding domain Dehydrin PF00257.14 CDI74933.1 - 9.5e-07 29.2 0.0 1.2e-05 25.6 1.4 9.3 5 4 0 5 5 5 2 Dehydrin DUF1764 PF08576.5 CDI74933.1 - 0.12 13.1 0.2 0.12 13.1 0.1 7.2 4 1 1 5 5 5 0 Eukaryotic protein of unknown function (DUF1764) Secretin_N_2 PF07655.8 CDI74934.1 - 0.79 10.1 36.6 0.14 12.5 7.4 3.3 3 0 0 3 3 3 0 Secretin N-terminal domain Pap_E4 PF02711.9 CDI74934.1 - 1.7 9.5 12.2 0.36 11.6 0.3 3.2 3 0 0 3 3 3 0 E4 protein SOBP PF15279.1 CDI74934.1 - 2.3 8.5 10.2 3.2 8.0 7.1 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein Mem_trans PF03547.13 CDI74935.1 - 0.013 13.8 8.9 0.015 13.6 6.2 1.1 1 0 0 1 1 1 0 Membrane transport protein Med15 PF09606.5 CDI74935.1 - 0.018 13.3 83.9 0.02 13.1 58.2 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal MRP-S31 PF15433.1 CDI74935.1 - 0.018 14.5 26.4 0.021 14.2 18.3 1.0 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 BPD_transp_2 PF02653.11 CDI74935.1 - 0.018 14.0 0.7 0.021 13.8 0.3 1.3 1 1 0 1 1 1 0 Branched-chain amino acid transport system / permease component DUF4131 PF13567.1 CDI74935.1 - 0.02 14.3 9.1 0.026 13.9 6.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) Bul1_N PF04425.7 CDI74935.1 - 0.069 11.7 17.6 0.081 11.4 12.2 1.0 1 0 0 1 1 1 0 Bul1 N terminus FLO_LFY PF01698.11 CDI74935.1 - 0.082 11.7 20.5 0.085 11.6 14.2 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein AMP-binding PF00501.23 CDI74935.1 - 0.12 10.7 7.0 0.15 10.4 4.9 1.1 1 0 0 1 1 1 0 AMP-binding enzyme GAGA_bind PF06217.7 CDI74935.1 - 0.13 12.2 20.3 0.15 12.0 14.1 1.0 1 0 0 1 1 1 0 GAGA binding protein-like family PAT1 PF09770.4 CDI74935.1 - 0.25 9.5 63.3 0.28 9.3 43.9 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Band_3_cyto PF07565.8 CDI74935.1 - 0.44 10.0 20.8 0.54 9.7 14.4 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain eIF-3_zeta PF05091.7 CDI74935.1 - 0.47 9.0 25.3 0.53 8.8 17.5 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Paramyxo_ncap PF00973.14 CDI74935.1 - 0.52 8.9 19.6 0.61 8.7 13.6 1.0 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein PA26 PF04636.8 CDI74935.1 - 0.54 8.8 13.1 0.59 8.7 9.1 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) DUF4045 PF13254.1 CDI74935.1 - 0.65 9.2 17.7 0.72 9.0 12.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) FAM60A PF15396.1 CDI74935.1 - 0.68 9.6 14.7 0.78 9.4 10.2 1.1 1 0 0 1 1 1 0 Protein Family FAM60A AUX_IAA PF02309.11 CDI74935.1 - 0.74 9.5 18.2 0.9 9.2 12.6 1.3 1 0 0 1 1 1 0 AUX/IAA family RR_TM4-6 PF06459.7 CDI74935.1 - 0.85 9.4 19.4 1 9.2 13.5 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Presenilin PF01080.12 CDI74935.1 - 0.91 8.2 14.9 0.93 8.2 10.3 1.1 1 0 0 1 1 1 0 Presenilin Tetraspannin PF00335.15 CDI74935.1 - 1.1 8.4 5.0 1.5 8.0 3.5 1.3 1 0 0 1 1 1 0 Tetraspanin family Peptidase_S64 PF08192.6 CDI74935.1 - 1.1 7.4 18.7 1.3 7.2 13.0 1.0 1 0 0 1 1 1 0 Peptidase family S64 DUF3260 PF11658.3 CDI74935.1 - 1.2 7.2 20.2 1.4 6.9 14.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3260) YABBY PF04690.8 CDI74935.1 - 1.2 9.3 14.0 1.5 9.0 9.7 1.3 1 0 0 1 1 1 0 YABBY protein Lipoprotein_X PF03305.8 CDI74935.1 - 1.4 8.2 13.8 2.4 7.4 9.6 1.4 1 0 0 1 1 1 0 Mycoplasma MG185/MG260 protein MMR1 PF08505.5 CDI74935.1 - 1.6 8.7 27.7 2.1 8.2 19.2 1.3 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein DUF4220 PF13968.1 CDI74935.1 - 1.6 7.7 6.6 1.9 7.5 4.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4220) Herpes_UL87 PF03043.9 CDI74935.1 - 1.8 6.8 13.6 1.9 6.7 9.4 1.1 1 0 0 1 1 1 0 Herpesvirus UL87 family Hid1 PF12722.2 CDI74935.1 - 2 5.9 21.3 2.2 5.8 14.8 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SAGA-Tad1 PF12767.2 CDI74935.1 - 2.1 7.9 26.3 2.7 7.5 18.2 1.2 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit Med19 PF10278.4 CDI74935.1 - 2.3 7.8 12.8 3 7.4 8.9 1.1 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 TFIIA PF03153.8 CDI74935.1 - 2.4 7.9 49.7 3.2 7.5 34.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Herpes_DNAp_acc PF04929.7 CDI74935.1 - 2.9 6.7 18.4 3.4 6.5 12.8 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Ycf1 PF05758.7 CDI74935.1 - 3.3 5.3 20.6 3.6 5.1 14.3 1.0 1 0 0 1 1 1 0 Ycf1 Ribosomal_60s PF00428.14 CDI74935.1 - 3.5 8.1 16.7 7.2 7.0 11.6 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein DUF913 PF06025.7 CDI74935.1 - 3.6 6.2 13.3 4.6 5.8 9.2 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) MRP-S26 PF14943.1 CDI74935.1 - 4.4 6.8 24.9 5.5 6.5 17.2 1.2 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 POR_N PF01855.14 CDI74935.1 - 4.7 6.6 12.0 6.1 6.2 8.3 1.1 1 0 0 1 1 1 0 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg Exonuc_VII_L PF02601.10 CDI74935.1 - 4.9 6.2 25.6 5 6.2 17.7 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit HCO3_cotransp PF00955.16 CDI74935.1 - 6.9 5.2 8.3 7.7 5.0 5.7 1.2 1 0 0 1 1 1 0 HCO3- transporter family Asp-B-Hydro_N PF05279.6 CDI74935.1 - 7.3 6.3 16.8 8.4 6.1 11.7 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Spore_coat_CotO PF14153.1 CDI74935.1 - 7.4 5.9 36.1 10 5.5 25.0 1.2 1 0 0 1 1 1 0 Spore coat protein CotO FNIP_N PF14636.1 CDI74935.1 - 8.2 6.9 23.2 12 6.3 16.1 1.3 1 0 0 1 1 1 0 Folliculin-interacting protein N-terminus Ndc1_Nup PF09531.5 CDI74935.1 - 8.6 4.6 20.2 9.8 4.4 14.0 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF342 PF03961.8 CDI74935.1 - 9 4.5 14.5 9.4 4.5 10.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) SseC PF04888.7 CDI74936.1 - 0.0012 18.2 22.1 0.0012 18.2 15.3 2.0 2 0 0 2 2 1 1 Secretion system effector C (SseC) like family PEX11 PF05648.9 CDI74936.1 - 0.0093 15.2 12.1 0.27 10.4 0.9 2.1 2 0 0 2 2 2 2 Peroxisomal biogenesis factor 11 (PEX11) Pex14_N PF04695.8 CDI74936.1 - 0.014 15.3 14.3 0.014 15.3 9.9 2.1 1 1 1 2 2 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Zip PF02535.17 CDI74936.1 - 0.017 14.1 1.7 0.024 13.6 1.2 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Ndc1_Nup PF09531.5 CDI74936.1 - 0.042 12.2 16.1 0.049 12.0 11.1 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup SAPS PF04499.10 CDI74936.1 - 0.044 12.4 13.6 0.055 12.1 9.4 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Utp14 PF04615.8 CDI74936.1 - 0.063 11.4 22.8 0.078 11.1 15.8 1.1 1 0 0 1 1 1 0 Utp14 protein DUF966 PF06136.8 CDI74936.1 - 0.068 12.5 18.6 0.086 12.2 12.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) TFIIF_beta PF02270.10 CDI74936.1 - 0.086 12.6 21.1 0.12 12.1 14.6 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, beta subunit PAT1 PF09770.4 CDI74936.1 - 0.096 10.9 52.2 0.11 10.6 36.2 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Spore_coat_CotO PF14153.1 CDI74936.1 - 0.1 12.0 33.0 0.26 10.7 5.8 2.1 2 0 0 2 2 2 0 Spore coat protein CotO PLRV_ORF5 PF01690.12 CDI74936.1 - 0.24 10.5 15.7 0.3 10.1 10.9 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein DUF4557 PF15101.1 CDI74936.1 - 0.28 10.9 41.9 0.36 10.6 9.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4557) RNA_pol_Rpb1_5 PF04998.12 CDI74936.1 - 0.32 10.1 8.9 0.5 9.5 6.1 1.3 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 Peptidase_M56 PF05569.6 CDI74936.1 - 0.33 9.8 6.3 0.44 9.4 4.4 1.1 1 0 0 1 1 1 0 BlaR1 peptidase M56 Ctr PF04145.10 CDI74936.1 - 0.36 10.8 21.5 0.087 12.8 4.1 2.2 1 1 1 2 2 2 0 Ctr copper transporter family DUF429 PF04250.8 CDI74936.1 - 0.44 9.7 10.4 0.62 9.2 7.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF429) DUF4094 PF13334.1 CDI74936.1 - 0.45 10.9 16.7 0.22 11.9 2.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4094) Apt1 PF10351.4 CDI74936.1 - 0.58 8.9 12.3 0.76 8.5 8.6 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF4175 PF13779.1 CDI74936.1 - 0.64 7.6 63.3 0.54 7.8 21.4 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4175) PBP1_TM PF14812.1 CDI74936.1 - 0.65 10.3 14.5 3.2 8.1 0.7 2.2 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF3357 PF11837.3 CDI74936.1 - 0.89 9.4 9.9 0.72 9.7 1.5 2.8 1 1 1 2 2 2 0 Domain of unknown function (DUF3357) DUF4355 PF14265.1 CDI74936.1 - 1.1 9.2 38.1 1.6 8.6 12.8 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4355) DUF4647 PF15504.1 CDI74936.1 - 1.1 7.9 25.1 1.6 7.5 17.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4647) DUF3347 PF11827.3 CDI74936.1 - 1.2 9.1 24.7 1.6 8.7 7.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3347) GPCR_chapero_1 PF11904.3 CDI74936.1 - 1.3 8.1 16.2 1.8 7.6 11.3 1.2 1 0 0 1 1 1 0 GPCR-chaperone FUSC PF04632.7 CDI74936.1 - 1.3 7.3 29.4 1.5 7.1 20.4 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family CD20 PF04103.10 CDI74936.1 - 1.4 8.8 9.9 1.2 9.0 0.2 2.3 2 0 0 2 2 2 0 CD20-like family GD_AH_C PF04295.8 CDI74936.1 - 1.5 7.4 12.0 2 7.0 8.4 1.3 1 0 0 1 1 1 0 D-galactarate dehydratase / Altronate hydrolase, C terminus CRT10 PF08728.5 CDI74936.1 - 1.5 6.7 9.2 1.8 6.4 6.4 1.0 1 0 0 1 1 1 0 CRT10 MRP-S31 PF15433.1 CDI74936.1 - 1.9 7.8 29.8 2.7 7.3 6.4 2.1 2 0 0 2 2 2 0 Mitochondrial 28S ribosomal protein S31 SDH_alpha PF03313.10 CDI74936.1 - 2 7.3 14.0 3.9 6.4 9.7 1.6 1 1 0 1 1 1 0 Serine dehydratase alpha chain Mak16 PF04874.9 CDI74936.1 - 2.3 8.3 14.8 1.1 9.3 1.9 2.3 2 0 0 2 2 2 0 Mak16 protein C-terminal region Herpes_UL87 PF03043.9 CDI74936.1 - 2.3 6.4 10.9 2.9 6.1 7.5 1.2 1 0 0 1 1 1 0 Herpesvirus UL87 family Bud13 PF09736.4 CDI74936.1 - 2.5 8.3 35.3 2.4 8.4 6.9 2.1 2 0 0 2 2 2 0 Pre-mRNA-splicing factor of RES complex DUF2232 PF09991.4 CDI74936.1 - 2.7 6.9 16.6 0.063 12.2 0.7 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2232) DUF4366 PF14283.1 CDI74936.1 - 2.7 7.3 22.3 1.3 8.3 14.2 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4366) Afi1 PF07792.7 CDI74936.1 - 2.7 7.9 22.0 3.9 7.4 4.7 2.1 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking DUF3402 PF11882.3 CDI74936.1 - 2.9 6.8 17.3 3.7 6.4 12.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3402) DUF4628 PF15429.1 CDI74936.1 - 3.2 7.1 16.5 0.63 9.4 2.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4628) Spore_YhcN_YlaJ PF09580.5 CDI74936.1 - 3.4 7.7 23.7 0.64 10.1 6.0 2.2 2 0 0 2 2 2 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) Herpes_DNAp_acc PF04929.7 CDI74936.1 - 3.9 6.3 16.2 4.9 6.0 11.3 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Sox_N PF12444.3 CDI74936.1 - 3.9 8.6 16.8 11 7.2 5.6 2.2 2 0 0 2 2 2 0 Sox developmental protein N terminal SR-25 PF10500.4 CDI74936.1 - 4.1 6.8 20.5 3.6 6.9 3.0 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein PAXIP1_C PF15364.1 CDI74936.1 - 4.3 7.2 22.0 2 8.3 3.6 2.1 2 0 0 2 2 2 0 PAXIP1-associated-protein-1 C term PTIP binding protein DUF2140 PF09911.4 CDI74936.1 - 5.3 6.1 10.5 2.8 7.0 0.3 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2140) Hid1 PF12722.2 CDI74936.1 - 7.2 4.1 24.5 9.5 3.7 17.0 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Rsc14 PF08586.5 CDI74936.1 - 8 7.0 14.8 10 6.6 2.3 2.4 2 0 0 2 2 2 0 RSC complex, Rsc14/Ldb7 subunit ATAD4 PF15321.1 CDI74936.1 - 8.8 7.4 24.6 4.2 8.4 5.3 2.3 2 0 0 2 2 2 0 ATPase family AAA domain containing 4 Endonuc_Holl PF10107.4 CDI74936.1 - 9.6 5.8 22.6 3.6 7.2 5.3 2.2 2 0 0 2 2 2 0 Endonuclease related to archaeal Holliday junction resolvase E1-E2_ATPase PF00122.15 CDI74937.1 - 1.5e-08 33.9 0.0 5.6e-08 32.1 0.0 2.0 1 1 0 1 1 1 1 E1-E2 ATPase SR-25 PF10500.4 CDI74937.1 - 0.00066 19.2 12.4 0.00066 19.2 8.6 8.6 7 1 1 8 8 8 1 Nuclear RNA-splicing-associated protein Ribosomal_60s PF00428.14 CDI74937.1 - 0.0076 16.6 20.3 0.0076 16.6 14.1 16.3 12 4 1 13 13 13 6 60s Acidic ribosomal protein Zip PF02535.17 CDI74938.1 - 0.00012 21.1 5.8 0.00021 20.4 4.0 1.4 1 0 0 1 1 1 1 ZIP Zinc transporter DUF1183 PF06682.7 CDI74938.1 - 0.01 15.4 19.4 0.021 14.4 13.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) Cellulose_synt PF03552.9 CDI74938.1 - 0.47 8.6 8.1 0.94 7.6 5.6 1.5 1 0 0 1 1 1 0 Cellulose synthase DUF2370 PF10176.4 CDI74938.1 - 1.7 7.9 16.5 2.5 7.3 10.5 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF2370) Plasmodium_Vir PF05795.6 CDI74938.1 - 2.4 7.2 7.2 4.4 6.3 5.0 1.4 1 0 0 1 1 1 0 Plasmodium vivax Vir protein DUF3337 PF11816.3 CDI74938.1 - 3.4 6.9 17.2 0.36 10.1 8.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3337) SID-1_RNA_chan PF13965.1 CDI74938.1 - 7.6 4.5 16.5 13 3.7 11.4 1.4 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 KH_1 PF00013.24 CDI74939.1 - 1.5e-22 78.9 0.0 1.3e-06 27.9 0.0 5.7 5 0 0 5 5 5 5 KH domain KH_3 PF13014.1 CDI74939.1 - 3.9e-08 32.7 0.0 0.12 12.0 0.0 4.4 4 0 0 4 4 4 2 KH domain BMC PF00936.14 CDI74939.1 - 0.0001 21.9 0.4 1.7 8.3 0.0 5.0 5 0 0 5 5 5 2 BMC domain KH_2 PF07650.12 CDI74939.1 - 0.017 14.6 8.7 1.5 8.3 0.0 4.4 4 1 0 4 4 4 0 KH domain KH_5 PF13184.1 CDI74939.1 - 0.12 12.2 0.3 2.7 7.8 0.0 3.2 3 0 0 3 3 3 0 NusA-like KH domain CTP_transf_2 PF01467.21 CDI74940.1 - 8.4e-18 64.9 0.1 2.5e-17 63.3 0.1 1.9 1 0 0 1 1 1 1 Cytidylyltransferase TBPIP PF07106.8 CDI74940.1 - 1.8 8.0 29.1 4.8 6.7 5.8 4.1 3 0 0 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) ATG16 PF08614.6 CDI74940.1 - 4.2 7.1 36.9 4.3 7.1 7.4 3.9 3 1 0 3 3 3 0 Autophagy protein 16 (ATG16) Seryl_tRNA_N PF02403.17 CDI74940.1 - 9.3 6.3 23.8 1.6 8.8 2.4 4.1 3 1 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Pribosyltran PF00156.22 CDI74941.1 - 2.6e-13 49.8 0.0 3.6e-13 49.3 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Phage_endo_I PF05367.6 CDI74941.1 - 0.041 13.2 0.0 0.065 12.6 0.0 1.3 1 0 0 1 1 1 0 Phage endonuclease I DUF4207 PF13904.1 CDI74942.1 - 0.075 12.3 25.8 0.15 11.4 17.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4207) Hid1 PF12722.2 CDI74942.1 - 0.13 9.8 11.3 0.14 9.8 7.8 1.3 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Suf PF05843.9 CDI74942.1 - 0.19 11.3 12.5 0.31 10.7 8.7 1.5 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) YjgP_YjgQ PF03739.9 CDI74942.1 - 0.33 9.6 2.1 0.42 9.3 1.4 1.2 1 0 0 1 1 1 0 Predicted permease YjgP/YjgQ family Herpes_DNAp_acc PF04929.7 CDI74942.1 - 0.66 8.8 15.4 1.1 8.1 10.7 1.4 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Herpes_LMP2 PF07415.6 CDI74942.1 - 2.3 6.7 14.4 0.27 9.7 6.9 1.6 1 1 1 2 2 2 0 Gammaherpesvirus latent membrane protein (LMP2) protein Cellulose_synt PF03552.9 CDI74942.1 - 3.3 5.8 6.3 4.5 5.4 4.4 1.1 1 0 0 1 1 1 0 Cellulose synthase CAF-1_p150 PF11600.3 CDI74942.1 - 4.9 6.4 30.1 0.33 10.2 15.9 2.1 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Herpes_UL87 PF03043.9 CDI74943.1 - 0.58 8.4 0.0 0.58 8.4 0.0 3.1 2 2 1 3 3 3 0 Herpesvirus UL87 family E_Pc_C PF06752.7 CDI74944.1 - 0.0027 17.2 8.4 0.0027 17.2 5.8 27.6 7 6 15 22 22 22 1 Enhancer of Polycomb C-terminus PBP1_TM PF14812.1 CDI74945.1 - 9.8e-05 22.5 3.1 9.8e-05 22.5 2.2 4.5 5 1 0 5 5 5 1 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF912 PF06024.7 CDI74945.1 - 0.0016 18.4 0.7 0.0016 18.4 0.5 7.8 8 0 0 8 8 8 1 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF3899 PF13038.1 CDI74945.1 - 0.042 13.9 0.4 0.042 13.9 0.3 3.3 3 1 0 3 3 3 0 Domain of unknown function (DUF3899) Pkinase PF00069.20 CDI74946.1 - 1.2e-32 113.1 0.0 1.6e-32 112.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain EF-hand_7 PF13499.1 CDI74946.1 - 6.1e-15 55.1 0.0 2.4e-08 33.9 0.2 2.7 2 1 1 3 3 3 2 EF-hand domain pair Pkinase_Tyr PF07714.12 CDI74946.1 - 2.4e-12 46.4 0.0 4.9e-12 45.4 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase EF-hand_1 PF00036.27 CDI74946.1 - 1.9e-11 42.4 0.9 0.00027 20.0 0.0 3.3 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.1 CDI74946.1 - 2.7e-11 42.3 1.0 0.00043 19.9 0.1 3.5 3 0 0 3 3 3 2 EF-hand domain EF-hand_5 PF13202.1 CDI74946.1 - 1.3e-07 30.5 7.1 0.0011 18.1 0.4 3.0 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.1 CDI74946.1 - 1.6e-06 27.5 2.1 0.077 12.6 0.1 3.4 2 1 1 3 3 3 2 EF-hand domain pair Kinase-like PF14531.1 CDI74946.1 - 7.3e-06 25.1 0.0 3.3e-05 22.9 0.0 2.0 1 1 1 2 2 2 1 Kinase-like EF-hand_4 PF12763.2 CDI74946.1 - 0.17 11.6 1.2 1.4 8.6 0.1 2.4 1 1 1 2 2 2 0 Cytoskeletal-regulatory complex EF hand FimP PF09766.4 CDI74947.1 - 0.0061 15.6 8.2 0.0065 15.5 5.7 1.1 1 0 0 1 1 1 1 Fms-interacting protein Spt20 PF12090.3 CDI74947.1 - 0.0086 15.4 5.3 0.0086 15.4 3.7 1.1 1 0 0 1 1 1 1 Spt20 family DivIC PF04977.10 CDI74947.1 - 0.028 13.9 9.9 0.034 13.6 6.8 1.2 1 0 0 1 1 1 0 Septum formation initiator RAB3GAP2_N PF14655.1 CDI74947.1 - 0.032 13.2 3.3 0.034 13.1 2.3 1.1 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Peptidase_S49_N PF08496.5 CDI74947.1 - 0.042 13.6 2.4 0.045 13.5 1.7 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF3357 PF11837.3 CDI74947.1 - 0.043 13.6 0.0 0.05 13.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) GRP PF07172.6 CDI74947.1 - 0.048 14.1 0.2 0.065 13.7 0.2 1.2 1 0 0 1 1 1 0 Glycine rich protein family Cnd1_N PF12922.2 CDI74947.1 - 0.049 13.2 3.2 0.064 12.8 2.2 1.1 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1, N-term ERK-JNK_inhib PF15002.1 CDI74947.1 - 0.05 12.9 6.0 0.059 12.7 4.2 1.1 1 0 0 1 1 1 0 ERK and JNK pathways, inhibitor Suf PF05843.9 CDI74947.1 - 0.063 13.0 5.1 0.059 13.0 3.5 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Conotoxin PF02950.12 CDI74947.1 - 0.064 14.0 1.8 0.12 13.1 1.2 1.6 1 0 0 1 1 1 0 Conotoxin Serinc PF03348.10 CDI74947.1 - 0.069 11.8 2.7 0.067 11.8 1.9 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) Med15 PF09606.5 CDI74947.1 - 0.1 10.8 19.5 0.11 10.7 13.5 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Folate_carrier PF01770.13 CDI74947.1 - 0.13 10.7 2.1 0.14 10.6 1.5 1.0 1 0 0 1 1 1 0 Reduced folate carrier FHIPEP PF00771.15 CDI74947.1 - 0.15 10.3 1.4 0.15 10.3 1.0 1.0 1 0 0 1 1 1 0 FHIPEP family zf-DHHC PF01529.15 CDI74947.1 - 0.17 11.2 1.0 0.19 11.0 0.7 1.2 1 0 0 1 1 1 0 DHHC palmitoyltransferase FAM91_C PF14648.1 CDI74947.1 - 0.19 10.5 1.8 0.19 10.5 1.2 1.0 1 0 0 1 1 1 0 FAM91 C-terminus Claudin_2 PF13903.1 CDI74947.1 - 0.2 11.3 1.2 0.25 11.0 0.9 1.1 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction DUF912 PF06024.7 CDI74947.1 - 0.24 11.4 1.3 0.29 11.2 0.9 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Band_3_cyto PF07565.8 CDI74947.1 - 0.25 10.8 3.9 0.25 10.8 2.7 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain DUF788 PF05620.6 CDI74947.1 - 0.25 11.1 8.3 0.35 10.7 5.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF788) RRP14 PF15459.1 CDI74947.1 - 0.26 11.3 14.2 0.39 10.8 9.8 1.3 1 0 0 1 1 1 0 60S ribosome biogenesis protein Rrp14 BAF1_ABF1 PF04684.8 CDI74947.1 - 0.3 9.8 14.9 0.32 9.7 10.4 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor RR_TM4-6 PF06459.7 CDI74947.1 - 0.33 10.7 5.7 0.37 10.6 3.9 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 EphA2_TM PF14575.1 CDI74947.1 - 0.34 11.3 1.3 0.46 10.9 0.9 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain ERF PF04404.7 CDI74947.1 - 0.35 10.4 12.2 0.43 10.1 8.4 1.2 1 0 0 1 1 1 0 ERF superfamily DUF4557 PF15101.1 CDI74947.1 - 0.52 10.1 9.8 0.56 10.0 6.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) Tom22 PF04281.8 CDI74947.1 - 0.58 9.6 6.2 0.77 9.2 4.3 1.2 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 TMEM51 PF15345.1 CDI74947.1 - 0.71 9.5 6.8 0.92 9.1 4.7 1.1 1 0 0 1 1 1 0 Transmembrane protein 51 DUF3373 PF11853.3 CDI74947.1 - 0.72 8.3 4.8 0.74 8.2 3.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) EIIBC-GUT_N PF03612.9 CDI74947.1 - 0.77 9.3 3.7 0.94 9.0 2.6 1.1 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus UPF0560 PF10577.4 CDI74947.1 - 0.82 7.8 8.4 0.87 7.7 5.9 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 DUF4407 PF14362.1 CDI74947.1 - 0.94 8.3 6.8 1 8.2 4.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF4647 PF15504.1 CDI74947.1 - 1.1 8.0 10.3 1.2 7.8 7.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4647) APC_CDC26 PF10471.4 CDI74947.1 - 1.2 9.8 19.3 2 9.1 13.4 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex APC subunit 1 DUF4207 PF13904.1 CDI74947.1 - 2.2 7.5 21.4 3.1 7.1 14.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4207) FCP1_C PF09309.5 CDI74947.1 - 3.1 7.0 12.2 4 6.6 8.5 1.1 1 0 0 1 1 1 0 FCP1, C-terminal SHR3_chaperone PF08229.6 CDI74947.1 - 4.8 6.0 9.5 6.2 5.7 6.6 1.1 1 0 0 1 1 1 0 ER membrane protein SH3 BRF1 PF07741.8 CDI74947.1 - 8.7 6.6 12.5 12 6.2 8.6 1.4 1 1 0 1 1 1 0 Brf1-like TBP-binding domain RAP1 PF07218.6 CDI74948.1 - 0.00044 18.5 11.4 0.00044 18.5 7.9 1.6 2 0 0 2 2 2 1 Rhoptry-associated protein 1 (RAP-1) Conotoxin PF02950.12 CDI74949.1 - 0.00028 21.6 12.5 0.077 13.7 0.3 2.1 2 0 0 2 2 2 2 Conotoxin DUF3357 PF11837.3 CDI74949.1 - 0.0034 17.2 6.5 0.16 11.8 0.2 2.1 1 1 1 2 2 2 2 Domain of unknown function (DUF3357) DUF2264 PF10022.4 CDI74949.1 - 0.0063 15.2 5.8 0.0075 14.9 4.0 1.0 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2264) DUF2782 PF11191.3 CDI74949.1 - 0.025 14.5 7.1 1 9.3 0.9 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2782) DUF2828 PF11443.3 CDI74949.1 - 0.16 10.1 8.2 0.18 9.9 5.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Spore_YhcN_YlaJ PF09580.5 CDI74949.1 - 0.17 11.9 16.2 0.19 11.8 11.3 1.1 1 0 0 1 1 1 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) DUF4336 PF14234.1 CDI74949.1 - 0.25 10.4 5.8 0.3 10.2 4.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4336) TCP PF03634.8 CDI74949.1 - 0.3 11.4 14.7 0.42 10.9 10.2 1.2 1 0 0 1 1 1 0 TCP family transcription factor Zip PF02535.17 CDI74949.1 - 0.46 9.4 6.7 0.53 9.2 4.6 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Neurensin PF14927.1 CDI74949.1 - 0.52 9.6 3.5 10 5.4 0.4 2.2 2 0 0 2 2 2 0 Neurensin TMEM154 PF15102.1 CDI74949.1 - 0.64 9.7 14.1 0.86 9.2 0.5 2.0 2 0 0 2 2 2 0 TMEM154 protein family CcmH PF03918.9 CDI74949.1 - 0.66 8.9 10.3 2.1 7.3 0.6 2.1 2 0 0 2 2 2 0 Cytochrome C biogenesis protein Baculo_PP31 PF05311.6 CDI74949.1 - 0.71 9.0 11.9 0.94 8.6 8.2 1.2 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) DDHD PF02862.12 CDI74949.1 - 0.89 9.3 13.6 1.2 8.8 9.4 1.2 1 0 0 1 1 1 0 DDHD domain DUF4512 PF14975.1 CDI74949.1 - 0.97 10.2 8.1 1.4 9.7 5.6 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4512) Herpes_UL87 PF03043.9 CDI74949.1 - 1.1 7.5 10.4 1.2 7.4 7.2 1.0 1 0 0 1 1 1 0 Herpesvirus UL87 family SID-1_RNA_chan PF13965.1 CDI74949.1 - 1.4 6.9 5.8 1.6 6.7 4.0 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 GRP PF07172.6 CDI74949.1 - 2 8.9 10.9 1.6 9.2 0.7 2.1 1 1 1 2 2 2 0 Glycine rich protein family AUX_IAA PF02309.11 CDI74949.1 - 2.1 8.0 13.7 2.5 7.7 9.5 1.1 1 0 0 1 1 1 0 AUX/IAA family Herpes_DNAp_acc PF04929.7 CDI74949.1 - 2.1 7.2 10.8 2.8 6.8 7.5 1.2 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Rtf2 PF04641.7 CDI74949.1 - 2.2 7.4 15.6 2.5 7.2 10.8 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger DUF4446 PF14584.1 CDI74949.1 - 2.4 7.9 10.4 3.1 7.5 7.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) GAGA_bind PF06217.7 CDI74949.1 - 2.5 7.9 15.3 2.7 7.8 10.6 1.0 1 0 0 1 1 1 0 GAGA binding protein-like family Neur_chan_memb PF02932.11 CDI74949.1 - 2.5 7.9 10.5 3.5 7.4 7.3 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region LTP_2 PF14368.1 CDI74949.1 - 3.2 7.9 6.0 16 5.6 0.3 2.3 2 0 0 2 2 2 0 Probable lipid transfer FLO_LFY PF01698.11 CDI74949.1 - 3.3 6.4 16.0 4.1 6.1 11.1 1.2 1 0 0 1 1 1 0 Floricaula / Leafy protein eIF-3_zeta PF05091.7 CDI74949.1 - 5.3 5.5 23.2 6 5.3 16.1 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) FliP PF00813.15 CDI74949.1 - 5.4 6.6 8.4 6.3 6.4 5.8 1.1 1 0 0 1 1 1 0 FliP family PCYCGC PF13798.1 CDI74949.1 - 8.5 6.0 17.4 6.8 6.3 8.6 2.0 1 1 1 2 2 2 0 Protein of unknown function with PCYCGC motif FAM60A PF15396.1 CDI74949.1 - 8.8 6.0 13.5 11 5.6 9.4 1.1 1 0 0 1 1 1 0 Protein Family FAM60A Med15 PF09606.5 CDI74951.1 - 0.00014 20.2 50.4 0.0002 19.7 5.4 4.0 4 0 0 4 4 4 3 ARC105 or Med15 subunit of Mediator complex non-fungal RED_N PF07808.8 CDI74954.1 - 0.0065 15.7 6.9 0.0065 15.7 4.8 4.0 3 1 1 4 4 4 1 RED-like protein N-terminal region BRICHOS PF04089.9 CDI74955.1 - 4 7.3 8.5 12 5.8 0.1 2.5 2 0 0 2 2 2 0 BRICHOS domain BUD22 PF09073.5 CDI74957.1 - 1.9e-06 27.2 14.2 1.9e-06 27.2 9.9 4.6 4 1 0 4 4 3 1 BUD22 Plasmodium_Vir PF05795.6 CDI74957.1 - 0.00035 19.8 1.6 0.00035 19.8 1.1 4.4 4 1 0 4 4 4 1 Plasmodium vivax Vir protein AAA_29 PF13555.1 CDI74957.1 - 0.00074 18.9 0.0 0.0018 17.7 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain cobW PF02492.14 CDI74957.1 - 0.0009 18.7 0.1 0.0026 17.2 0.0 1.9 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.1 CDI74957.1 - 0.0011 18.9 0.0 0.0011 18.9 0.0 4.3 4 1 0 4 4 2 1 AAA ATPase domain AAA_18 PF13238.1 CDI74957.1 - 0.0019 18.5 0.0 0.0019 18.5 0.0 3.9 4 2 0 4 4 3 1 AAA domain AAA_17 PF13207.1 CDI74957.1 - 0.0021 18.8 0.7 0.011 16.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 CDI74957.1 - 0.0026 17.9 0.0 0.01 15.9 0.0 2.1 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 CDI74957.1 - 0.0081 16.3 0.0 0.034 14.3 0.0 2.2 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) MobB PF03205.9 CDI74957.1 - 0.18 11.5 0.0 0.18 11.5 0.0 2.2 2 0 0 2 2 1 0 Molybdopterin guanine dinucleotide synthesis protein B Miro PF08477.8 CDI74957.1 - 0.98 9.9 0.0 0.98 9.9 0.0 4.5 6 0 0 6 6 4 0 Miro-like protein Med15 PF09606.5 CDI74957.1 - 5.5 5.0 128.9 1.2 7.1 13.9 3.3 3 0 0 3 3 3 0 ARC105 or Med15 subunit of Mediator complex non-fungal rve PF00665.21 CDI74958.1 - 6.8e-20 71.3 2.6 5.8e-19 68.3 0.0 3.5 5 0 0 5 5 5 1 Integrase core domain rve_3 PF13683.1 CDI74958.1 - 9.8e-05 21.8 1.0 5.5 6.6 0.0 4.7 3 1 1 4 4 4 2 Integrase core domain DUF3038 PF11237.3 CDI74958.1 - 0.12 12.1 2.2 0.19 11.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3038) Chromo PF00385.19 CDI74959.1 - 1.4e-08 34.2 0.0 2.2e-08 33.6 0.0 1.2 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Gpi1 PF05024.10 CDI74960.1 - 2.8e-08 33.6 2.4 5.3e-08 32.7 0.2 2.1 2 0 0 2 2 2 1 N-acetylglucosaminyl transferase component (Gpi1) DUF3208 PF11482.3 CDI74961.1 - 0.0011 19.0 0.3 0.003 17.6 0.2 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3208) TSSC4 PF15264.1 CDI74961.1 - 0.024 15.0 0.0 0.056 13.8 0.0 1.7 1 1 0 1 1 1 0 Tumour suppressing sub-chromosomal transferable candidate 4 DUF3953 PF13129.1 CDI74962.1 - 0.73 9.5 4.8 13 5.5 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3953) DEAD PF00270.24 CDI74964.1 - 5.2e-07 29.3 0.0 8.9e-07 28.5 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase SR-25 PF10500.4 CDI74967.1 - 0.011 15.2 13.7 0.012 15.0 9.5 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Shadoo PF14999.1 CDI74967.1 - 0.02 14.7 5.3 0.022 14.6 3.7 1.2 1 0 0 1 1 1 0 Shadow of prion protein, neuroprotective TRM13 PF05206.9 CDI74967.1 - 0.069 12.3 9.9 0.07 12.3 6.8 1.1 1 0 0 1 1 1 0 Methyltransferase TRM13 Med15 PF09606.5 CDI74967.1 - 0.17 10.0 62.3 0.19 9.9 43.2 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Velvet PF11754.3 CDI74967.1 - 0.46 10.0 10.8 0.51 9.9 7.5 1.0 1 0 0 1 1 1 0 Velvet factor Glyco_transf_8 PF01501.15 CDI74967.1 - 0.46 9.7 4.9 0.6 9.4 3.4 1.2 1 0 0 1 1 1 0 Glycosyl transferase family 8 MRP-S31 PF15433.1 CDI74967.1 - 0.54 9.6 27.5 0.62 9.4 19.1 1.0 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 Activator_LAG-3 PF11498.3 CDI74967.1 - 0.9 8.2 59.8 1.1 7.9 41.5 1.0 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Spore_coat_CotO PF14153.1 CDI74967.1 - 1.4 8.3 27.6 1.6 8.1 19.1 1.1 1 0 0 1 1 1 0 Spore coat protein CotO 2OG-FeII_Oxy_5 PF13759.1 CDI74967.1 - 1.4 9.2 8.1 2.1 8.6 5.6 1.3 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase Peptidase_S49_N PF08496.5 CDI74967.1 - 1.6 8.5 16.1 2 8.2 11.2 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Baculo_PP31 PF05311.6 CDI74967.1 - 1.8 7.7 18.2 1.9 7.7 12.6 1.1 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) CDC45 PF02724.9 CDI74967.1 - 2.4 6.0 17.2 2.7 5.9 11.9 1.0 1 0 0 1 1 1 0 CDC45-like protein FLO_LFY PF01698.11 CDI74967.1 - 2.6 6.8 20.2 3 6.6 14.0 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein Peptidase_S15 PF02129.13 CDI74967.1 - 2.7 7.3 17.6 3.2 7.1 12.2 1.0 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Lin-8 PF03353.10 CDI74967.1 - 2.7 7.1 20.3 3.1 7.0 14.1 1.0 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist HemX PF04375.9 CDI74967.1 - 3.1 6.2 37.6 3.6 6.0 26.1 1.0 1 0 0 1 1 1 0 HemX Band_3_cyto PF07565.8 CDI74967.1 - 3.3 7.1 19.4 3.6 7.0 13.4 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain SID-1_RNA_chan PF13965.1 CDI74967.1 - 4.4 5.3 10.5 4.3 5.3 7.3 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Draxin PF15550.1 CDI74967.1 - 4.9 6.7 14.8 6 6.4 10.3 1.1 1 0 0 1 1 1 0 Draxin DUF2048 PF09752.4 CDI74967.1 - 5.2 5.8 11.1 5.7 5.7 7.7 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2048) PCEMA1 PF07418.6 CDI74967.1 - 5.2 6.3 10.1 5.4 6.2 7.0 1.0 1 0 0 1 1 1 0 Acidic phosphoprotein precursor PCEMA1 PMSI1 PF15322.1 CDI74967.1 - 5.2 6.0 19.9 5.9 5.8 13.8 1.1 1 0 0 1 1 1 0 Protein missing in infertile sperm 1, putative DUF4446 PF14584.1 CDI74967.1 - 5.4 6.8 10.7 6.9 6.4 7.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) RNA_pol_Rpb1_5 PF04998.12 CDI74967.1 - 5.5 6.1 11.0 5.7 6.1 7.6 1.0 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 DDHD PF02862.12 CDI74967.1 - 6.3 6.5 18.3 6.8 6.4 12.7 1.1 1 0 0 1 1 1 0 DDHD domain AUX_IAA PF02309.11 CDI74967.1 - 6.8 6.3 16.0 7 6.3 11.1 1.1 1 0 0 1 1 1 0 AUX/IAA family PAT1 PF09770.4 CDI74967.1 - 6.8 4.7 45.8 7.2 4.7 31.7 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Gag_spuma PF03276.9 CDI74967.1 - 7.2 4.8 28.6 7.7 4.7 19.8 1.3 1 0 0 1 1 1 0 Spumavirus gag protein Neur_chan_memb PF02932.11 CDI74967.1 - 7.4 6.3 14.8 7.8 6.3 10.3 1.0 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region GAGA_bind PF06217.7 CDI74967.1 - 7.5 6.4 19.2 7.8 6.3 13.3 1.0 1 0 0 1 1 1 0 GAGA binding protein-like family UPF0052 PF01933.13 CDI74967.1 - 7.5 5.7 10.3 8.5 5.6 7.1 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0052 DUF3381 PF11861.3 CDI74967.1 - 8 5.9 19.5 10 5.6 13.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) Helicase_RecD PF05127.9 CDI74967.1 - 9.2 5.8 13.5 11 5.5 9.4 1.2 1 0 0 1 1 1 0 Helicase YABBY PF04690.8 CDI74967.1 - 9.3 6.4 13.1 11 6.1 9.1 1.3 1 0 0 1 1 1 0 YABBY protein eIF-3_zeta PF05091.7 CDI74967.1 - 9.4 4.7 22.2 9.3 4.7 15.4 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF4367 PF14285.1 CDI74967.1 - 9.7 5.4 11.1 16 4.7 7.7 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4367) Med19 PF10278.4 CDI74967.1 - 9.8 5.8 13.1 12 5.5 9.1 1.1 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 RskA PF10099.4 CDI74968.1 - 0.014 15.1 4.1 0.014 15.1 2.8 5.4 3 1 0 4 4 4 0 Anti-sigma-K factor rskA P12 PF12669.2 CDI74968.1 - 0.016 15.4 1.1 0.041 14.0 0.7 1.8 1 0 0 1 1 1 0 Virus attachment protein p12 family Ribosomal_60s PF00428.14 CDI74968.1 - 0.22 11.9 6.0 0.56 10.6 4.2 1.7 1 0 0 1 1 1 0 60s Acidic ribosomal protein Utp14 PF04615.8 CDI74969.1 - 3 5.9 64.4 3.8 5.5 44.6 1.0 1 0 0 1 1 1 0 Utp14 protein DUF2052 PF09747.4 CDI74970.1 - 0.0017 18.3 12.3 0.002 18.0 8.6 1.1 1 0 0 1 1 1 1 Coiled-coil domain containing protein (DUF2052) Suf PF05843.9 CDI74970.1 - 0.01 15.5 15.5 0.013 15.2 10.7 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF912 PF06024.7 CDI74970.1 - 0.014 15.4 6.3 0.022 14.8 4.4 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF913 PF06025.7 CDI74970.1 - 0.017 13.8 2.9 0.018 13.7 2.0 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DUF853 PF05872.7 CDI74970.1 - 0.042 12.2 10.3 0.046 12.0 7.2 1.0 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) PAT1 PF09770.4 CDI74970.1 - 0.05 11.8 28.8 0.053 11.7 19.9 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 RIC3 PF15361.1 CDI74970.1 - 0.051 13.8 10.5 0.07 13.3 7.3 1.2 1 0 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 eIF-3_zeta PF05091.7 CDI74970.1 - 0.057 12.0 14.0 0.058 12.0 9.7 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DDHD PF02862.12 CDI74970.1 - 0.064 13.0 8.0 0.071 12.8 5.6 1.2 1 0 0 1 1 1 0 DDHD domain DUF4557 PF15101.1 CDI74970.1 - 0.082 12.7 19.6 0.095 12.5 13.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) DUF433 PF04255.9 CDI74970.1 - 0.088 12.2 0.1 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF433) Dala_Dala_lig_N PF01820.16 CDI74970.1 - 0.14 12.4 3.3 0.17 12.1 2.3 1.4 1 0 0 1 1 1 0 D-ala D-ala ligase N-terminus AAA_11 PF13086.1 CDI74970.1 - 0.15 11.6 13.0 0.17 11.4 9.0 1.1 1 0 0 1 1 1 0 AAA domain hDGE_amylase PF14701.1 CDI74970.1 - 0.15 10.9 7.1 0.16 10.8 4.9 1.1 1 0 0 1 1 1 0 glucanotransferase domain of human glycogen debranching enzyme Baculo_PP31 PF05311.6 CDI74970.1 - 0.16 11.2 13.3 0.19 10.9 9.2 1.1 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) SID-1_RNA_chan PF13965.1 CDI74970.1 - 0.16 10.0 4.7 0.17 9.9 3.3 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Peroxin-13_N PF04088.8 CDI74970.1 - 0.18 11.7 4.0 0.21 11.5 2.7 1.2 1 0 0 1 1 1 0 Peroxin 13, N-terminal region Folate_carrier PF01770.13 CDI74970.1 - 0.18 10.2 8.0 0.21 10.0 5.6 1.1 1 0 0 1 1 1 0 Reduced folate carrier FAM60A PF15396.1 CDI74970.1 - 0.2 11.3 6.9 0.2 11.3 4.8 1.2 1 0 0 1 1 1 0 Protein Family FAM60A AIF_C PF14721.1 CDI74970.1 - 0.21 11.8 5.4 0.25 11.5 3.7 1.3 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term EIIBC-GUT_N PF03612.9 CDI74970.1 - 0.21 11.2 8.8 0.27 10.8 6.1 1.1 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Peptidase_S49_N PF08496.5 CDI74970.1 - 0.25 11.1 13.2 0.32 10.7 9.2 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF4192 PF13830.1 CDI74970.1 - 0.29 10.7 4.9 0.34 10.5 3.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4192) MDFI PF15316.1 CDI74970.1 - 0.34 10.8 2.1 0.41 10.6 1.5 1.1 1 0 0 1 1 1 0 MyoD family inhibitor Peptidase_U57 PF05582.7 CDI74970.1 - 0.35 9.7 7.9 0.39 9.6 5.5 1.1 1 0 0 1 1 1 0 YabG peptidase U57 Afi1 PF07792.7 CDI74970.1 - 0.36 10.8 11.9 0.42 10.6 8.3 1.2 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Band_3_cyto PF07565.8 CDI74970.1 - 0.4 10.1 13.1 0.46 9.9 9.1 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain FLO_LFY PF01698.11 CDI74970.1 - 0.41 9.4 10.4 0.44 9.3 7.2 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein CPSF100_C PF13299.1 CDI74970.1 - 0.46 10.6 9.5 0.56 10.3 6.6 1.1 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal DUF2828 PF11443.3 CDI74970.1 - 0.5 8.4 12.7 0.58 8.3 8.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) DUF2347 PF09804.4 CDI74970.1 - 0.55 9.4 8.9 0.64 9.2 6.2 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2347) RskA PF10099.4 CDI74970.1 - 0.55 9.9 11.6 1 9.1 8.0 1.4 1 1 0 1 1 1 0 Anti-sigma-K factor rskA RR_TM4-6 PF06459.7 CDI74970.1 - 0.73 9.6 12.7 0.81 9.5 8.8 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Peptidase_S15 PF02129.13 CDI74970.1 - 0.78 9.1 8.8 0.89 8.9 6.1 1.2 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) OATP PF03137.15 CDI74970.1 - 0.83 7.6 7.5 0.94 7.4 5.2 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family DUF3347 PF11827.3 CDI74970.1 - 0.85 9.6 16.3 0.76 9.7 10.7 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3347) Serinc PF03348.10 CDI74970.1 - 0.93 8.1 9.6 1 8.0 6.6 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) Neur_chan_memb PF02932.11 CDI74970.1 - 1 9.1 5.7 1.1 9.0 4.0 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Kei1 PF08552.6 CDI74970.1 - 1.1 8.8 6.2 1.4 8.5 4.3 1.2 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 Ctr PF04145.10 CDI74970.1 - 1.4 8.9 10.3 2.1 8.3 7.1 1.3 1 0 0 1 1 1 0 Ctr copper transporter family Nucleoside_tran PF01733.13 CDI74970.1 - 1.4 7.9 6.8 1.8 7.6 4.7 1.1 1 0 0 1 1 1 0 Nucleoside transporter DUF2203 PF09969.4 CDI74970.1 - 1.6 9.0 9.5 2.2 8.4 6.6 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) DUF775 PF05603.7 CDI74970.1 - 1.7 8.1 11.8 1.9 7.9 8.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF775) DUF1800 PF08811.6 CDI74970.1 - 1.7 7.4 23.0 2 7.2 15.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1800) Gti1_Pac2 PF09729.4 CDI74970.1 - 1.8 8.4 9.0 2.2 8.1 6.3 1.2 1 0 0 1 1 1 0 Gti1/Pac2 family SprA-related PF12118.3 CDI74970.1 - 2 7.6 31.0 2.4 7.4 21.5 1.2 1 0 0 1 1 1 0 SprA-related family TFIIA PF03153.8 CDI74970.1 - 2 8.2 25.1 2 8.2 17.4 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Paramyxo_ncap PF00973.14 CDI74970.1 - 2.1 6.9 9.3 2 6.9 6.4 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Glyco_transf_15 PF01793.11 CDI74970.1 - 2.8 6.7 12.2 3.5 6.4 8.5 1.1 1 0 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase Tom37_C PF11801.3 CDI74970.1 - 3.2 7.5 21.0 3.9 7.2 14.6 1.1 1 0 0 1 1 1 0 Tom37 C-terminal domain DDRGK PF09756.4 CDI74970.1 - 3.4 7.0 22.6 4.3 6.6 15.7 1.1 1 0 0 1 1 1 0 DDRGK domain YABBY PF04690.8 CDI74970.1 - 3.4 7.8 8.0 4.5 7.5 5.5 1.3 1 0 0 1 1 1 0 YABBY protein NinG PF05766.7 CDI74970.1 - 3.4 7.3 16.9 4.5 6.9 11.7 1.1 1 0 0 1 1 1 0 Bacteriophage Lambda NinG protein DUF4175 PF13779.1 CDI74970.1 - 3.5 5.2 41.4 4 5.0 28.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) LMBR1 PF04791.11 CDI74970.1 - 3.8 5.9 7.5 4.1 5.8 5.2 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein Presenilin PF01080.12 CDI74970.1 - 3.9 6.1 6.1 4.4 6.0 4.2 1.1 1 0 0 1 1 1 0 Presenilin Plasmodium_Vir PF05795.6 CDI74970.1 - 4.7 6.3 6.0 5 6.2 4.2 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein GvpL_GvpF PF06386.6 CDI74970.1 - 5 6.6 16.4 6.8 6.1 11.4 1.2 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF DUF1764 PF08576.5 CDI74970.1 - 6.9 7.5 16.3 11 6.8 11.3 1.3 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) Tho2 PF11262.3 CDI74970.1 - 7.2 5.5 15.8 9 5.2 11.0 1.1 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Glyco_transf_6 PF03414.8 CDI74970.1 - 7.6 4.8 10.2 9.5 4.5 7.1 1.1 1 0 0 1 1 1 0 Glycosyltransferase family 6 OmpH PF03938.9 CDI74970.1 - 7.8 6.4 38.9 10 6.0 27.0 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF1980 PF09323.5 CDI74970.1 - 8.1 6.1 11.2 9.8 5.8 7.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) Med15 PF09606.5 CDI74970.1 - 8.1 4.4 49.2 9.2 4.3 34.1 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Glt_symporter PF03616.9 CDI74970.1 - 8.3 4.7 5.6 11 4.3 3.9 1.3 1 0 0 1 1 1 0 Sodium/glutamate symporter CRF1 PF10380.4 CDI74970.1 - 8.5 6.7 9.1 11 6.4 6.3 1.3 1 0 0 1 1 1 0 Transcription factor CRF1 DUF3464 PF11947.3 CDI74970.1 - 8.9 5.7 12.1 12 5.3 8.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) AAA_23 PF13476.1 CDI74971.1 - 0.0007 19.9 12.4 0.0007 19.9 8.6 3.6 3 1 0 3 3 3 1 AAA domain zf-CCHC_2 PF13696.1 CDI74972.1 - 3.2e-07 29.7 0.4 5.7e-07 28.9 0.3 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.18 CDI74972.1 - 0.051 13.5 4.8 0.093 12.6 3.3 1.4 1 0 0 1 1 1 0 Zinc knuckle LIM_bind PF01803.11 CDI74972.1 - 0.11 11.6 6.7 0.16 11.0 0.5 2.3 2 0 0 2 2 2 0 LIM-domain binding protein zf-CCHC_4 PF14392.1 CDI74972.1 - 1 9.0 3.9 1.7 8.3 2.7 1.3 1 0 0 1 1 1 0 Zinc knuckle RAB3GAP2_N PF14655.1 CDI74972.1 - 2.5 7.0 14.5 0.76 8.7 0.7 2.2 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus DUF4109 PF13397.1 CDI74972.1 - 4.6 7.6 7.8 0.32 11.4 0.8 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4109) DUF912 PF06024.7 CDI74972.1 - 7.5 6.6 7.6 10 6.2 0.6 2.9 2 1 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Med15 PF09606.5 CDI74973.1 - 0.0073 14.5 83.8 0.0091 14.2 58.1 1.2 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal GAGA_bind PF06217.7 CDI74973.1 - 0.45 10.4 22.2 0.48 10.3 15.4 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family Band_3_cyto PF07565.8 CDI74973.1 - 1.2 8.5 28.7 1.7 8.1 19.9 1.3 1 0 0 1 1 1 0 Band 3 cytoplasmic domain PAT1 PF09770.4 CDI74973.1 - 1.5 6.9 65.8 1.6 6.8 45.6 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Exonuc_VII_L PF02601.10 CDI74973.1 - 1.6 7.8 28.5 2.2 7.3 19.8 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit Herpes_UL87 PF03043.9 CDI74973.1 - 6.5 5.0 14.5 7.6 4.7 10.1 1.2 1 0 0 1 1 1 0 Herpesvirus UL87 family PRP1_N PF06424.7 CDI74973.1 - 7.9 6.8 18.9 13 6.0 13.1 1.4 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal APG6 PF04111.7 CDI74973.1 - 8.3 5.3 36.4 10 5.0 25.2 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 RR_TM4-6 PF06459.7 CDI74973.1 - 8.5 6.1 25.3 12 5.6 17.5 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Pyr_redox_2 PF07992.9 CDI74976.1 - 0.073 12.9 0.1 0.086 12.7 0.1 1.1 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase CDK2AP PF09806.4 CDI74976.1 - 0.16 12.2 7.1 0.2 11.8 4.9 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein TFIIA PF03153.8 CDI74976.1 - 0.85 9.4 14.5 1 9.1 10.0 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit zf-C4H2 PF10146.4 CDI74976.1 - 2.7 7.9 6.9 4 7.3 4.8 1.4 1 1 0 1 1 1 0 Zinc finger-containing protein Menin PF05053.8 CDI74976.1 - 3.6 5.6 7.2 4 5.4 5.0 1.0 1 0 0 1 1 1 0 Menin PsbW PF07123.7 CDI74976.1 - 8.6 6.4 8.5 13 5.8 5.7 1.4 1 1 0 1 1 1 0 Photosystem II reaction centre W protein (PsbW) Med13_N PF11597.3 CDI74976.1 - 9.2 4.8 8.0 0.24 10.0 1.3 1.4 2 0 0 2 2 2 0 Mediator complex subunit 13 N-terminal FimP PF09766.4 CDI74977.1 - 0.0015 17.6 7.9 0.0015 17.6 5.5 12.6 6 3 4 10 10 10 2 Fms-interacting protein DUF3343 PF11823.3 CDI74977.1 - 0.0023 17.1 0.0 4.6 6.5 0.0 3.3 2 0 0 2 2 2 2 Protein of unknown function (DUF3343) CD20 PF04103.10 CDI74977.1 - 0.0091 15.9 0.4 0.0091 15.9 0.3 8.1 8 2 0 8 8 8 1 CD20-like family Herpes_DNAp_acc PF04929.7 CDI74977.1 - 0.0097 14.9 0.0 0.0097 14.9 0.0 8.2 3 3 3 6 6 6 1 Herpes DNA replication accessory factor Med15 PF09606.5 CDI74980.1 - 0.0006 18.1 26.2 0.0008 17.7 18.2 1.2 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal OmpH PF03938.9 CDI74980.1 - 0.043 13.7 20.2 0.085 12.7 14.0 1.5 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF4175 PF13779.1 CDI74980.1 - 0.088 10.5 24.2 0.14 9.8 16.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Pex14_N PF04695.8 CDI74980.1 - 0.2 11.6 22.3 0.62 10.1 7.6 2.3 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Afi1 PF07792.7 CDI74980.1 - 0.61 10.0 11.8 1.2 9.1 3.7 2.2 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking V_ATPase_I PF01496.14 CDI74980.1 - 1 7.0 8.7 1.5 6.5 6.1 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF3138 PF11336.3 CDI74980.1 - 1.1 7.3 11.5 1.7 6.7 8.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Bul1_N PF04425.7 CDI74980.1 - 1.2 7.6 12.9 0.49 8.8 3.8 2.1 2 0 0 2 2 2 0 Bul1 N terminus FAM176 PF14851.1 CDI74980.1 - 1.2 8.8 10.0 1.9 8.1 3.0 2.3 2 0 0 2 2 2 0 FAM176 family DUF3154 PF11351.3 CDI74980.1 - 1.3 8.7 7.0 3 7.6 4.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3154) TFIIA PF03153.8 CDI74980.1 - 1.4 8.7 25.1 1.9 8.3 17.4 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit AUX_IAA PF02309.11 CDI74980.1 - 1.5 8.4 10.9 5.4 6.6 0.3 2.2 2 0 0 2 2 2 0 AUX/IAA family SR-25 PF10500.4 CDI74980.1 - 1.6 8.1 36.0 1.4 8.3 12.9 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein FimP PF09766.4 CDI74980.1 - 2.5 7.0 21.1 0.64 9.0 10.5 2.1 2 0 0 2 2 2 0 Fms-interacting protein ATAD4 PF15321.1 CDI74980.1 - 2.6 9.1 14.4 5.9 7.9 3.8 2.5 2 0 0 2 2 2 0 ATPase family AAA domain containing 4 Ctr PF04145.10 CDI74980.1 - 3.1 7.8 8.9 8.5 6.4 2.6 2.4 2 0 0 2 2 2 0 Ctr copper transporter family PEX11 PF05648.9 CDI74980.1 - 4.8 6.3 8.9 1.8 7.7 2.8 2.0 2 0 0 2 2 2 0 Peroxisomal biogenesis factor 11 (PEX11) Folate_carrier PF01770.13 CDI74980.1 - 6.6 5.1 10.1 0.86 8.0 2.9 1.9 2 0 0 2 2 2 0 Reduced folate carrier Band_3_cyto PF07565.8 CDI74980.1 - 7.1 6.0 19.7 7.2 6.0 7.2 2.1 2 0 0 2 2 2 0 Band 3 cytoplasmic domain CDC27 PF09507.5 CDI74982.1 - 0.0027 17.0 48.4 0.0046 16.2 33.6 1.3 1 0 0 1 1 1 1 DNA polymerase subunit Cdc27 TraT PF05818.7 CDI74982.1 - 0.0039 16.6 11.4 0.0039 16.6 7.9 2.2 1 1 1 2 2 1 1 Enterobacterial TraT complement resistance protein PAT1 PF09770.4 CDI74982.1 - 0.0062 14.8 68.5 0.0087 14.3 47.5 1.2 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 Med15 PF09606.5 CDI74982.1 - 0.086 11.0 92.9 0.13 10.4 64.4 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal SAGA-Tad1 PF12767.2 CDI74982.1 - 0.098 12.3 31.1 0.15 11.6 21.6 1.4 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit GAGA_bind PF06217.7 CDI74982.1 - 0.55 10.1 30.2 0.77 9.6 20.9 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family AIF_C PF14721.1 CDI74982.1 - 0.57 10.4 0.0 0.57 10.4 0.0 3.2 1 1 2 3 3 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term BTV_NS2 PF04514.7 CDI74982.1 - 1.2 7.8 28.0 1.7 7.4 19.4 1.3 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Herpes_UL87 PF03043.9 CDI74982.1 - 4.8 5.4 14.9 6.3 5.0 10.3 1.2 1 0 0 1 1 1 0 Herpesvirus UL87 family FAM60A PF15396.1 CDI74982.1 - 4.9 6.8 28.8 10 5.8 19.9 1.6 1 0 0 1 1 1 0 Protein Family FAM60A Caldesmon PF02029.10 CDI74982.1 - 6.2 5.1 42.4 8.3 4.6 29.4 1.1 1 0 0 1 1 1 0 Caldesmon Pkinase PF00069.20 CDI74984.1 - 4.5e-20 71.8 0.2 6.2e-15 55.0 0.1 2.6 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CDI74984.1 - 3.5e-10 39.3 0.5 3.5e-07 29.5 0.1 3.0 2 1 1 3 3 3 2 Protein tyrosine kinase IncA PF04156.9 CDI74985.1 - 0.47 10.0 9.6 0.8 9.2 6.7 1.4 1 0 0 1 1 1 0 IncA protein RAB3GAP2_N PF14655.1 CDI74985.1 - 0.51 9.2 3.4 0.69 8.8 2.4 1.1 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus PC_rep PF01851.17 CDI74987.1 - 8.3e-12 44.6 32.0 0.00029 20.9 0.1 9.1 9 0 0 9 9 9 5 Proteasome/cyclosome repeat HEAT_2 PF13646.1 CDI74987.1 - 0.0015 18.7 8.7 0.075 13.3 0.0 5.0 4 1 1 5 5 5 1 HEAT repeats HEAT_EZ PF13513.1 CDI74987.1 - 0.74 10.3 8.7 26 5.4 0.0 5.0 4 0 0 4 4 4 0 HEAT-like repeat PI3_PI4_kinase PF00454.22 CDI74989.1 - 1.2e-25 90.3 0.0 2.1e-25 89.5 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF1980 PF09323.5 CDI74990.1 - 0.0027 17.4 0.3 0.0051 16.5 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1980) Pex14_N PF04695.8 CDI74990.1 - 0.009 16.0 5.6 0.009 16.0 3.9 3.9 2 1 1 3 3 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region BRF1 PF07741.8 CDI74990.1 - 0.0095 16.1 0.2 0.0095 16.1 0.1 3.0 2 1 0 2 2 1 1 Brf1-like TBP-binding domain RIC3 PF15361.1 CDI74990.1 - 0.033 14.4 0.4 0.033 14.4 0.3 2.9 2 1 0 2 2 2 0 Resistance to inhibitors of cholinesterase homologue 3 Band_3_cyto PF07565.8 CDI74990.1 - 0.12 11.9 2.7 0.18 11.3 0.2 2.0 2 0 0 2 2 2 0 Band 3 cytoplasmic domain FimP PF09766.4 CDI74990.1 - 0.13 11.3 13.1 0.23 10.4 9.1 1.3 1 0 0 1 1 1 0 Fms-interacting protein Pex16 PF08610.5 CDI74990.1 - 0.78 8.6 5.4 0.12 11.3 0.7 1.7 2 0 0 2 2 2 0 Peroxisomal membrane protein (Pex16) Insulin PF00049.13 CDI74990.1 - 1.2 9.9 8.6 1.1 10.0 3.4 2.4 2 0 0 2 2 2 0 Insulin/IGF/Relaxin family DUF912 PF06024.7 CDI74990.1 - 1.4 9.0 4.7 0.33 11.0 0.4 2.0 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF1071 PF06378.6 CDI74990.1 - 1.7 7.7 9.0 3.1 6.9 6.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1071) Plasmodium_Vir PF05795.6 CDI74990.1 - 2.1 7.4 3.2 31 3.6 2.3 2.0 1 1 0 1 1 1 0 Plasmodium vivax Vir protein Spt20 PF12090.3 CDI74990.1 - 3 7.1 10.9 5.5 6.2 7.5 1.3 1 0 0 1 1 1 0 Spt20 family Conotoxin PF02950.12 CDI74990.1 - 7.2 7.4 8.7 1.8 9.4 2.5 2.5 2 0 0 2 2 2 0 Conotoxin YjgP_YjgQ PF03739.9 CDI74991.1 - 1.2 7.8 8.7 2.3 6.8 6.1 1.6 1 0 0 1 1 1 0 Predicted permease YjgP/YjgQ family Med15 PF09606.5 CDI74992.1 - 0.017 13.3 21.3 0.021 13.0 14.7 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal FLO_LFY PF01698.11 CDI74992.1 - 0.12 11.2 3.4 0.14 10.9 2.4 1.2 1 0 0 1 1 1 0 Floricaula / Leafy protein FxsA PF04186.8 CDI74992.1 - 0.73 9.4 3.2 1.5 8.4 2.2 1.5 1 0 0 1 1 1 0 FxsA cytoplasmic membrane protein Activator_LAG-3 PF11498.3 CDI74992.1 - 0.96 8.1 20.3 1.6 7.4 14.1 1.3 1 0 0 1 1 1 0 Transcriptional activator LAG-3 TFIIA PF03153.8 CDI74992.1 - 4.8 6.9 17.7 5.7 6.7 12.3 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RAB3GAP2_N PF14655.1 CDI74992.1 - 5.2 5.9 9.2 6 5.7 6.3 1.4 1 1 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Claudin_2 PF13903.1 CDI74992.1 - 6.4 6.4 6.2 9.2 5.9 4.3 1.4 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction NCD2 PF04905.8 CDI74992.1 - 7.3 6.3 7.0 1.2 8.8 1.1 1.9 1 1 1 2 2 2 0 NAB conserved region 2 (NCD2) Ion_trans PF00520.26 CDI74994.1 - 1.6e-39 135.2 56.6 7.2e-17 61.2 4.7 4.3 4 0 0 4 4 4 4 Ion transport protein ETRAMP PF09716.5 CDI74994.1 - 0.89 9.5 4.4 0.42 10.5 0.0 2.8 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) Activator_LAG-3 PF11498.3 CDI74995.1 - 0.00086 18.1 11.7 0.00086 18.1 8.1 4.1 4 0 0 4 4 4 1 Transcriptional activator LAG-3 Med15 PF09606.5 CDI74995.1 - 0.0024 16.1 113.6 0.06 11.5 68.4 2.1 2 0 0 2 2 2 2 ARC105 or Med15 subunit of Mediator complex non-fungal Mitofilin PF09731.4 CDI74995.1 - 4.5 5.8 50.4 0.44 9.1 25.4 2.3 2 0 0 2 2 2 0 Mitochondrial inner membrane protein SLD3 PF08639.5 CDI74997.1 - 0.02 13.5 16.1 0.02 13.5 11.2 1.1 1 0 0 1 1 1 0 DNA replication regulator SLD3 SAGA-Tad1 PF12767.2 CDI74997.1 - 0.14 11.8 15.0 0.15 11.7 10.4 1.2 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit PRCH PF03967.8 CDI74997.1 - 0.24 10.9 9.3 0.23 11.0 5.9 1.3 1 1 0 1 1 1 0 Photosynthetic reaction centre, H-chain N-terminal region Band_3_cyto PF07565.8 CDI74997.1 - 0.31 10.4 14.4 0.34 10.3 10.0 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Arb1 PF09692.5 CDI74997.1 - 0.47 9.2 7.6 0.62 8.8 5.2 1.2 1 0 0 1 1 1 0 Argonaute siRNA chaperone (ARC) complex subunit Arb1 PAT1 PF09770.4 CDI74997.1 - 0.59 8.3 43.1 0.73 8.0 29.9 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 CDK5_activator PF03261.10 CDI74997.1 - 1.3 8.3 21.3 1.6 8.0 14.7 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein Gag_spuma PF03276.9 CDI74997.1 - 1.6 6.9 25.7 1.7 6.8 17.8 1.2 1 0 0 1 1 1 0 Spumavirus gag protein Mem_trans PF03547.13 CDI74997.1 - 2 6.6 8.5 2.3 6.3 5.9 1.1 1 0 0 1 1 1 0 Membrane transport protein Pex16 PF08610.5 CDI74997.1 - 2.1 7.2 12.5 2.9 6.8 8.6 1.3 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) DUF4045 PF13254.1 CDI74997.1 - 2.5 7.2 20.9 3 7.0 14.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Hid1 PF12722.2 CDI74997.1 - 2.9 5.4 21.1 3.2 5.2 14.6 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein GPCR_chapero_1 PF11904.3 CDI74997.1 - 3 6.8 12.8 3.3 6.7 8.9 1.2 1 0 0 1 1 1 0 GPCR-chaperone DUF4638 PF15472.1 CDI74997.1 - 3.8 7.0 12.7 4.2 6.8 8.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) DUF966 PF06136.8 CDI74997.1 - 4.2 6.7 18.9 5 6.4 13.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) DUF45 PF01863.12 CDI74997.1 - 4.3 7.0 11.7 5.1 6.8 8.1 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF45 SAPS PF04499.10 CDI74997.1 - 4.4 5.8 17.9 5.4 5.5 12.4 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Neur_chan_memb PF02932.11 CDI74997.1 - 4.9 6.9 15.3 5.5 6.8 10.6 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region CRT10 PF08728.5 CDI74997.1 - 5.5 4.8 7.8 5.7 4.8 5.4 1.0 1 0 0 1 1 1 0 CRT10 UPF0560 PF10577.4 CDI74997.1 - 7.2 4.7 23.7 8.2 4.5 16.4 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 G-7-MTase PF12803.2 CDI74997.1 - 7.7 5.5 8.9 8.4 5.4 6.1 1.1 1 0 0 1 1 1 0 mRNA (guanine-7-)methyltransferase (G-7-MTase) Ycf1 PF05758.7 CDI74997.1 - 7.9 4.0 16.4 8.1 4.0 11.4 1.0 1 0 0 1 1 1 0 Ycf1 eIF-3_zeta PF05091.7 CDI74997.1 - 8.2 4.9 21.1 9 4.7 14.6 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) IncA PF04156.9 CDI74997.1 - 9.1 5.8 27.0 11 5.5 18.7 1.2 1 0 0 1 1 1 0 IncA protein Plasmodium_Vir PF05795.6 CDI74997.1 - 9.8 5.2 6.6 11 5.1 4.6 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein PLRV_ORF5 PF01690.12 CDI74997.1 - 9.8 5.1 21.6 12 4.9 14.9 1.0 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Spt20 PF12090.3 CDI75001.1 - 0.0075 15.6 9.2 0.09 12.1 0.9 2.2 2 0 0 2 2 2 2 Spt20 family PAP_RNA-bind PF04926.10 CDI75001.1 - 0.01 15.3 0.5 0.77 9.2 0.2 2.1 2 0 0 2 2 2 0 Poly(A) polymerase predicted RNA binding domain DUF4557 PF15101.1 CDI75001.1 - 0.014 15.2 6.7 0.014 15.2 4.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4557) DUF2722 PF10846.3 CDI75001.1 - 0.015 14.3 12.4 0.07 12.1 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) DUF912 PF06024.7 CDI75001.1 - 0.044 13.8 1.0 1 9.4 0.1 2.3 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DDHD PF02862.12 CDI75001.1 - 0.056 13.2 1.5 0.086 12.6 1.1 1.3 1 0 0 1 1 1 0 DDHD domain CD20 PF04103.10 CDI75001.1 - 0.072 13.0 3.0 0.12 12.2 0.0 2.2 1 1 1 2 2 2 0 CD20-like family DUF3371 PF11851.3 CDI75001.1 - 0.082 13.5 13.8 1.2 9.8 0.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3371) Inhibitor_I71 PF12628.2 CDI75001.1 - 0.1 12.2 1.4 0.39 10.3 0.1 1.9 2 0 0 2 2 2 0 Falstatin, cysteine peptidase inhibitor DUF4366 PF14283.1 CDI75001.1 - 0.11 11.9 10.1 1.6 8.1 3.5 2.3 1 1 0 2 2 2 0 Domain of unknown function (DUF4366) IER PF05760.7 CDI75001.1 - 0.11 12.3 17.8 0.14 12.0 12.3 1.1 1 0 0 1 1 1 0 Immediate early response protein (IER) Presenilin PF01080.12 CDI75001.1 - 0.23 10.2 3.3 0.3 9.8 2.3 1.2 1 0 0 1 1 1 0 Presenilin FNIP_N PF14636.1 CDI75001.1 - 0.28 11.6 6.9 1.4 9.3 2.1 2.1 2 0 0 2 2 2 0 Folliculin-interacting protein N-terminus Ndc1_Nup PF09531.5 CDI75001.1 - 0.41 9.0 6.2 0.5 8.7 4.3 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup MRF_C2 PF13888.1 CDI75001.1 - 0.41 10.4 3.3 6.2 6.6 0.1 2.1 2 0 0 2 2 2 0 Myelin gene regulatory factor C-terminal domain 2 Peptidase_S49_N PF08496.5 CDI75001.1 - 0.45 10.3 4.6 0.95 9.2 0.6 2.2 2 0 0 2 2 2 0 Peptidase family S49 N-terminal FimP PF09766.4 CDI75001.1 - 0.46 9.4 18.0 0.081 11.9 3.2 2.0 2 0 0 2 2 2 0 Fms-interacting protein DUF3464 PF11947.3 CDI75001.1 - 0.63 9.4 7.5 2.3 7.6 0.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3464) Pex14_N PF04695.8 CDI75001.1 - 0.68 9.9 27.7 1.7 8.7 9.5 2.3 1 1 1 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Parvo_coat PF00740.13 CDI75001.1 - 0.86 8.4 8.7 1 8.2 6.0 1.1 1 0 0 1 1 1 0 Parvovirus coat protein VP2 Slp PF03843.8 CDI75001.1 - 1.2 8.1 6.9 0.62 9.0 1.3 2.1 2 0 0 2 2 2 0 Outer membrane lipoprotein Slp family E7 PF00527.13 CDI75001.1 - 2 8.6 7.7 5.1 7.3 0.5 2.2 2 0 0 2 2 2 0 E7 protein, Early protein Pap_E4 PF02711.9 CDI75001.1 - 2.4 9.0 9.7 1.1 10.1 0.5 2.2 2 0 0 2 2 2 0 E4 protein DUF2867 PF11066.3 CDI75001.1 - 3.1 7.5 9.2 0.51 10.0 3.6 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2867) DUF3043 PF11241.3 CDI75001.1 - 3.2 7.3 9.8 1.5 8.3 2.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3043) ARGLU PF15346.1 CDI75001.1 - 4.5 7.0 16.7 2 8.1 4.8 2.1 2 0 0 2 2 2 0 Arginine and glutamate-rich 1 RAB3GAP2_N PF14655.1 CDI75001.1 - 5.5 5.8 16.9 0.85 8.5 2.8 2.1 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus U1snRNP70_N PF12220.3 CDI75001.1 - 8.6 6.7 14.7 10 6.5 3.3 2.2 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal DUF4199 PF13858.1 CDI75001.1 - 9.8 6.0 10.5 0.47 10.3 1.0 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF4199) DUF605 PF04652.11 CDI75002.1 - 3.3 7.0 33.8 4 6.7 23.4 1.0 1 0 0 1 1 1 0 Vta1 like Mito_fiss_reg PF05308.6 CDI75003.1 - 0.00012 21.5 9.8 0.00014 21.3 6.8 1.0 1 0 0 1 1 1 1 Mitochondrial fission regulator DUF4653 PF15546.1 CDI75003.1 - 0.0047 16.2 4.7 0.0057 15.9 3.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4653) Corona_nucleoca PF00937.13 CDI75003.1 - 0.017 14.0 9.7 0.021 13.7 6.7 1.0 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein Phostensin_N PF13916.1 CDI75003.1 - 0.035 14.1 13.6 0.092 12.7 9.2 1.9 2 1 0 2 2 2 0 PP1-regulatory protein, Phostensin N-terminal Apt1 PF10351.4 CDI75003.1 - 0.045 12.5 2.3 0.056 12.2 1.6 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain Activator_LAG-3 PF11498.3 CDI75003.1 - 0.13 11.0 16.7 0.18 10.5 11.6 1.3 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Syntaphilin PF15290.1 CDI75003.1 - 0.32 10.4 7.9 0.4 10.1 5.5 1.2 1 0 0 1 1 1 0 Golgi-localised syntaxin-1-binding clamp Senescence_reg PF04520.8 CDI75003.1 - 0.33 11.4 5.4 0.41 11.1 3.7 1.1 1 0 0 1 1 1 0 Senescence regulator DUF2489 PF10675.4 CDI75003.1 - 0.55 9.9 8.9 0.74 9.4 6.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2489) Conotoxin PF02950.12 CDI75003.1 - 1.3 9.8 4.5 12 6.7 1.8 2.1 2 0 0 2 2 2 0 Conotoxin CAP_N PF01213.14 CDI75003.1 - 3.5 6.8 8.8 5.9 6.0 6.1 1.4 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal DUF605 PF04652.11 CDI75003.1 - 7.8 5.7 19.0 9.9 5.4 13.1 1.1 1 0 0 1 1 1 0 Vta1 like DUF1517 PF07466.6 CDI75003.1 - 8.4 5.2 8.7 14 4.5 6.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1517) Init_tRNA_PT PF04179.7 CDI75004.1 - 0.99 8.1 11.0 1.3 7.8 7.6 1.1 1 0 0 1 1 1 0 Initiator tRNA phosphoribosyl transferase Med15 PF09606.5 CDI75005.1 - 0.00028 19.2 51.6 0.019 13.1 19.5 2.2 2 0 0 2 2 2 2 ARC105 or Med15 subunit of Mediator complex non-fungal DUF3347 PF11827.3 CDI75005.1 - 0.089 12.7 15.2 0.024 14.6 2.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3347) BAF1_ABF1 PF04684.8 CDI75005.1 - 0.14 10.9 48.6 0.13 11.0 16.4 2.6 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor Spt20 PF12090.3 CDI75005.1 - 0.4 9.9 16.5 0.18 11.1 0.3 2.4 2 0 0 2 2 2 0 Spt20 family Tetraspannin PF00335.15 CDI75005.1 - 0.67 9.1 3.1 5.3 6.2 0.2 2.3 2 0 0 2 2 2 0 Tetraspanin family Band_3_cyto PF07565.8 CDI75005.1 - 0.87 9.0 13.6 2.6 7.4 2.4 2.5 2 0 0 2 2 2 0 Band 3 cytoplasmic domain FimP PF09766.4 CDI75005.1 - 1.4 7.9 27.0 0.26 10.2 2.7 2.1 2 0 0 2 2 2 0 Fms-interacting protein Sec62 PF03839.11 CDI75005.1 - 1.7 8.0 6.6 0.49 9.7 0.7 2.1 2 0 0 2 2 2 0 Translocation protein Sec62 PAT1 PF09770.4 CDI75005.1 - 1.9 6.6 42.6 0.75 7.9 13.9 2.1 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 DUF4175 PF13779.1 CDI75005.1 - 2.1 5.9 47.7 0.2 9.3 17.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4175) Spore_coat_CotO PF14153.1 CDI75005.1 - 3.3 7.1 21.0 2.4 7.5 4.1 2.2 2 0 0 2 2 2 0 Spore coat protein CotO E7 PF00527.13 CDI75005.1 - 6.9 6.8 15.3 0.97 9.6 2.4 2.7 2 0 0 2 2 2 0 E7 protein, Early protein OmpH PF03938.9 CDI75005.1 - 7.8 6.4 48.3 8.1 6.3 18.2 2.4 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) VIT1 PF01988.14 CDI75006.1 - 0.0033 16.9 2.6 0.0033 16.9 1.8 2.4 1 1 1 2 2 2 1 VIT family Ribosomal_60s PF00428.14 CDI75006.1 - 2 8.8 10.9 0.91 9.9 2.4 2.8 3 0 0 3 3 3 0 60s Acidic ribosomal protein CybS PF05328.7 CDI75006.1 - 2.4 7.7 5.9 0.49 10.0 1.2 2.1 1 1 0 2 2 2 0 CybS DDOST_48kD PF03345.9 CDI75009.1 - 8.1e-31 106.9 0.0 3.4e-28 98.3 0.0 2.1 2 0 0 2 2 2 2 Oligosaccharyltransferase 48 kDa subunit beta Med15 PF09606.5 CDI75010.1 - 8.8 4.3 21.4 0.42 8.7 8.8 2.2 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal SR-25 PF10500.4 CDI75010.1 - 9.8 5.5 15.2 0.82 9.0 4.0 2.5 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Hid1 PF12722.2 CDI75011.1 - 4.3 4.8 23.7 5.4 4.5 16.4 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein cwf18 PF08315.7 CDI75013.1 - 0.35 11.3 5.1 0.088 13.2 0.3 2.2 2 1 0 2 2 2 0 cwf18 pre-mRNA splicing factor DUF3681 PF12442.3 CDI75014.1 - 0.0082 16.3 4.7 0.047 13.8 0.1 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF3681) Chorion_2 PF03964.10 CDI75014.1 - 5.5 7.6 14.6 3.8 8.1 2.2 2.3 2 0 0 2 2 2 0 Chorion family 2 Med3 PF11593.3 CDI75014.1 - 9.2 5.3 10.5 11 5.1 7.3 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal LRR_4 PF12799.2 CDI75015.1 - 0.0022 17.5 1.8 0.0064 16.0 1.2 1.7 1 0 0 1 1 1 1 Leucine Rich repeats (2 copies) DUF912 PF06024.7 CDI75016.1 - 0.0026 17.7 0.2 0.0026 17.7 0.1 2.8 3 1 0 3 3 3 1 Nucleopolyhedrovirus protein of unknown function (DUF912) OAD_gamma PF04277.8 CDI75016.1 - 0.11 12.8 0.3 0.11 12.8 0.2 4.9 5 1 0 5 5 5 0 Oxaloacetate decarboxylase, gamma chain Mem_trans PF03547.13 CDI75016.1 - 0.39 8.9 1.8 1.2 7.4 1.4 1.5 1 1 0 1 1 1 0 Membrane transport protein Pox_RNA_Pol_19 PF05320.7 CDI75016.1 - 5.4 6.7 8.0 10 5.8 5.6 1.4 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit RAP1 PF07218.6 CDI75016.1 - 9.4 4.1 11.4 15 3.5 7.9 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DnaJ PF00226.26 CDI75017.1 - 2e-12 46.6 0.1 8e-12 44.7 0.0 2.1 1 0 0 1 1 1 1 DnaJ domain DUF1510 PF07423.6 CDI75018.1 - 5.5e-06 25.9 4.6 5.5e-06 25.9 3.2 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF1510) DUF3366 PF11846.3 CDI75018.1 - 0.0001 22.2 0.4 0.00019 21.3 0.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3366) YfhO PF09586.5 CDI75018.1 - 0.00017 19.7 0.5 0.00018 19.6 0.3 1.2 1 0 0 1 1 1 1 Bacterial membrane protein YfhO DUF4131 PF13567.1 CDI75018.1 - 0.00042 19.7 4.8 0.00042 19.7 3.4 1.7 1 1 1 2 2 2 1 Domain of unknown function (DUF4131) Med19 PF10278.4 CDI75018.1 - 0.014 15.0 4.8 0.014 15.0 3.4 1.8 2 0 0 2 2 2 0 Mediator of RNA pol II transcription subunit 19 YqfQ PF14181.1 CDI75018.1 - 0.035 14.1 22.3 0.058 13.4 0.6 3.0 3 0 0 3 3 3 0 YqfQ-like protein Herpes_UL87 PF03043.9 CDI75018.1 - 0.036 12.4 2.3 0.039 12.3 1.6 1.2 1 0 0 1 1 1 0 Herpesvirus UL87 family Methyltransf_26 PF13659.1 CDI75018.1 - 0.068 13.2 0.0 0.076 13.0 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Cas1_AcylT PF07779.7 CDI75018.1 - 0.075 11.4 0.2 0.13 10.6 0.1 1.4 1 0 0 1 1 1 0 10 TM Acyl Transferase domain found in Cas1p DUF3959 PF13105.1 CDI75018.1 - 0.081 12.2 1.3 0.13 11.5 0.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3959) Reticulon PF02453.12 CDI75018.1 - 0.085 12.4 0.9 0.15 11.6 0.1 1.8 1 1 1 2 2 2 0 Reticulon RNA_pol_Rpb1_5 PF04998.12 CDI75018.1 - 0.38 9.9 7.8 0.55 9.4 5.4 1.2 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 DUF4010 PF13194.1 CDI75018.1 - 0.38 10.0 4.2 0.31 10.3 1.9 1.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4010) DUF4097 PF13349.1 CDI75018.1 - 0.4 10.1 2.2 2.7 7.4 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4097) Claudin_2 PF13903.1 CDI75018.1 - 0.55 9.8 7.6 0.2 11.3 3.4 1.7 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction UPF0697 PF15117.1 CDI75018.1 - 1.9 8.3 10.3 0.15 11.8 1.7 2.5 2 0 0 2 2 2 0 Uncharacterised protein family UPF0697 DUF3278 PF11683.3 CDI75018.1 - 2.9 7.9 6.5 1 9.3 0.1 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF3278) DUF3260 PF11658.3 CDI75018.1 - 3.4 5.7 13.5 0.039 12.1 2.4 2.2 1 1 1 3 3 3 0 Protein of unknown function (DUF3260) FHIPEP PF00771.15 CDI75018.1 - 4.8 5.3 20.4 0.029 12.7 2.7 2.5 1 1 2 3 3 3 0 FHIPEP family hDGE_amylase PF14701.1 CDI75018.1 - 5.1 5.8 11.7 7.3 5.3 8.1 1.1 1 0 0 1 1 1 0 glucanotransferase domain of human glycogen debranching enzyme DUF2146 PF10220.4 CDI75018.1 - 5.4 4.8 17.1 0.88 7.4 9.5 1.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2146) Androgen_recep PF02166.11 CDI75018.1 - 7.2 5.3 19.1 4 6.1 8.4 2.2 2 0 0 2 2 2 0 Androgen receptor RskA PF10099.4 CDI75018.1 - 9.9 5.8 16.6 6.7 6.4 9.3 2.3 2 1 0 2 2 2 0 Anti-sigma-K factor rskA TFIIA PF03153.8 CDI75019.1 - 0.12 12.2 32.1 0.19 11.5 15.9 2.0 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit FimP PF09766.4 CDI75019.1 - 0.16 11.0 14.5 0.22 10.5 10.1 1.1 1 0 0 1 1 1 0 Fms-interacting protein Spt20 PF12090.3 CDI75019.1 - 0.34 10.2 7.1 0.55 9.5 4.9 1.3 1 0 0 1 1 1 0 Spt20 family Claudin_2 PF13903.1 CDI75019.1 - 1.1 8.9 8.1 2.7 7.6 1.4 2.2 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction DUF912 PF06024.7 CDI75019.1 - 7.5 6.6 5.5 17 5.5 3.8 1.6 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Endonuclease_NS PF01223.18 CDI75020.1 - 7.8e-07 28.9 0.0 3.4e-06 26.8 0.0 1.9 1 1 0 1 1 1 1 DNA/RNA non-specific endonuclease SNase PF00565.12 CDI75022.1 - 4e-10 39.9 2.0 3.5e-05 24.0 0.0 3.2 3 2 0 3 3 3 2 Staphylococcal nuclease homologue DUF3675 PF12428.3 CDI75022.1 - 0.0017 18.6 0.6 0.021 15.0 0.2 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3675) Prominin PF05478.6 CDI75022.1 - 0.014 12.9 0.5 0.021 12.4 0.3 1.1 1 0 0 1 1 1 0 Prominin DUF912 PF06024.7 CDI75022.1 - 0.069 13.2 0.2 0.069 13.2 0.1 3.9 3 1 1 4 4 4 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF4448 PF14610.1 CDI75022.1 - 0.1 12.0 1.5 0.12 11.8 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4448) Gemini_mov PF01708.11 CDI75022.1 - 0.11 12.0 0.2 0.43 10.1 0.1 2.0 1 0 0 1 1 1 0 Geminivirus putative movement protein YjgP_YjgQ PF03739.9 CDI75022.1 - 0.12 11.0 3.9 0.33 9.6 2.7 1.6 1 0 0 1 1 1 0 Predicted permease YjgP/YjgQ family COX15-CtaA PF02628.10 CDI75022.1 - 0.13 11.0 0.0 0.33 9.7 0.0 1.5 2 0 0 2 2 2 0 Cytochrome oxidase assembly protein PBP1_TM PF14812.1 CDI75022.1 - 8.3 6.7 8.0 73 3.7 5.6 2.6 1 1 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Band_3_cyto PF07565.8 CDI75022.1 - 8.5 5.8 15.9 3.3 7.1 5.2 3.0 3 0 0 3 3 3 0 Band 3 cytoplasmic domain MIP-T3 PF10243.4 CDI75025.1 - 2.2 6.6 56.7 2.3 6.5 39.3 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Utp14 PF04615.8 CDI75025.1 - 7.3 4.6 56.2 7.7 4.5 38.9 1.0 1 0 0 1 1 1 0 Utp14 protein Macoilin PF09726.4 CDI75026.1 - 1.3 7.2 9.4 1.9 6.6 6.5 1.3 1 0 0 1 1 1 0 Transmembrane protein Pex14_N PF04695.8 CDI75026.1 - 5 7.1 12.9 0.71 9.9 1.0 2.9 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region UCH PF00443.24 CDI75029.1 - 4.6e-36 124.3 0.0 4.4e-35 121.0 0.0 2.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CDI75029.1 - 6.2e-11 42.2 0.0 6.2e-11 42.2 0.0 3.6 4 1 0 4 4 4 2 Ubiquitin carboxyl-terminal hydrolase Clp1 PF06807.9 CDI75029.1 - 0.14 11.8 0.0 0.3 10.8 0.0 1.4 1 0 0 1 1 1 0 Pre-mRNA cleavage complex II protein Clp1 Ycf1 PF05758.7 CDI75031.1 - 0.051 11.3 21.0 0.055 11.1 14.5 1.0 1 0 0 1 1 1 0 Ycf1 Rtf2 PF04641.7 CDI75031.1 - 0.11 11.6 16.2 0.12 11.5 11.2 1.0 1 0 0 1 1 1 0 Rtf2 RING-finger Mem_trans PF03547.13 CDI75031.1 - 0.19 10.0 9.6 0.2 9.8 6.7 1.0 1 0 0 1 1 1 0 Membrane transport protein DUF4045 PF13254.1 CDI75031.1 - 0.27 10.4 17.3 0.31 10.2 12.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Gastrin PF00918.12 CDI75031.1 - 0.35 11.7 25.5 0.47 11.2 17.7 1.2 1 0 0 1 1 1 0 Gastrin/cholecystokinin family DDHD PF02862.12 CDI75031.1 - 0.73 9.5 16.6 0.87 9.3 11.5 1.1 1 0 0 1 1 1 0 DDHD domain Pneumo_phosprot PF02478.11 CDI75031.1 - 0.73 9.3 5.5 0.82 9.1 3.8 1.0 1 0 0 1 1 1 0 Pneumovirus phosphoprotein Raftlin PF15250.1 CDI75031.1 - 1.2 7.6 18.6 1.3 7.5 12.9 1.0 1 0 0 1 1 1 0 Raftlin Tim54 PF11711.3 CDI75031.1 - 1.2 7.6 15.0 1.4 7.4 10.4 1.0 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Peptidase_U57 PF05582.7 CDI75031.1 - 1.4 7.7 15.9 1.8 7.4 11.0 1.2 1 0 0 1 1 1 0 YabG peptidase U57 Peptidase_S64 PF08192.6 CDI75031.1 - 1.7 6.9 15.9 1.7 6.8 11.0 1.0 1 0 0 1 1 1 0 Peptidase family S64 Baculo_PP31 PF05311.6 CDI75031.1 - 1.7 7.8 16.5 2.6 7.2 11.4 1.4 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) FHIPEP PF00771.15 CDI75031.1 - 1.9 6.6 14.2 2.2 6.4 9.9 1.1 1 0 0 1 1 1 0 FHIPEP family Zip PF02535.17 CDI75031.1 - 2 7.3 8.0 2.5 7.0 5.6 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Erythro_esteras PF05139.9 CDI75031.1 - 2.1 7.4 17.1 2.6 7.1 11.8 1.1 1 0 0 1 1 1 0 Erythromycin esterase DUF342 PF03961.8 CDI75031.1 - 2.4 6.4 22.3 2.8 6.2 15.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) GBP_C PF02841.9 CDI75031.1 - 2.4 7.2 35.2 2.9 6.9 24.4 1.1 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain VID27 PF08553.5 CDI75031.1 - 2.5 6.2 16.1 2.6 6.1 11.1 1.0 1 0 0 1 1 1 0 VID27 cytoplasmic protein TCP PF03634.8 CDI75031.1 - 2.6 8.4 19.4 3.7 7.9 13.4 1.3 1 0 0 1 1 1 0 TCP family transcription factor SOBP PF15279.1 CDI75031.1 - 2.7 8.2 24.5 3.1 8.0 17.0 1.0 1 0 0 1 1 1 0 Sine oculis-binding protein FLO_LFY PF01698.11 CDI75031.1 - 3 6.6 19.6 3.5 6.3 13.6 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein HCO3_cotransp PF00955.16 CDI75031.1 - 3.6 6.1 8.4 4 5.9 5.9 1.0 1 0 0 1 1 1 0 HCO3- transporter family Hid1 PF12722.2 CDI75031.1 - 3.7 5.1 23.1 4 4.9 16.0 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF2201_N PF13203.1 CDI75031.1 - 3.8 6.6 21.5 4.3 6.4 14.9 1.0 1 0 0 1 1 1 0 Putative metallopeptidase domain FAM60A PF15396.1 CDI75031.1 - 4.1 7.0 18.1 4.7 6.8 12.6 1.1 1 0 0 1 1 1 0 Protein Family FAM60A AUX_IAA PF02309.11 CDI75031.1 - 4.5 6.9 18.6 5.3 6.7 12.9 1.1 1 0 0 1 1 1 0 AUX/IAA family Peptidase_S15 PF02129.13 CDI75031.1 - 4.7 6.5 17.5 5.6 6.2 12.1 1.1 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) CDC45 PF02724.9 CDI75031.1 - 4.9 5.0 19.3 5.8 4.8 13.4 1.0 1 0 0 1 1 1 0 CDC45-like protein Med15 PF09606.5 CDI75031.1 - 4.9 5.2 75.5 5.3 5.1 52.3 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal CAML PF14963.1 CDI75031.1 - 5 6.4 7.0 5.8 6.1 4.9 1.1 1 0 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand PCEMA1 PF07418.6 CDI75031.1 - 5 6.3 14.2 6.2 6.1 9.8 1.0 1 0 0 1 1 1 0 Acidic phosphoprotein precursor PCEMA1 RR_TM4-6 PF06459.7 CDI75031.1 - 5.1 6.9 22.5 6.2 6.6 15.6 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF4220 PF13968.1 CDI75031.1 - 5.5 5.9 10.2 5.9 5.8 7.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4220) DUF940 PF06082.6 CDI75031.1 - 5.8 5.3 14.4 5.9 5.3 10.0 1.1 1 0 0 1 1 1 0 Bacterial putative lipoprotein (DUF940) RNA_pol_Rpb1_5 PF04998.12 CDI75031.1 - 5.9 6.0 14.5 6.7 5.8 10.1 1.1 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 LicD PF04991.8 CDI75031.1 - 6.1 6.8 6.9 7.8 6.5 4.7 1.2 1 0 0 1 1 1 0 LicD family SID-1_RNA_chan PF13965.1 CDI75031.1 - 6.8 4.7 14.8 7.8 4.5 10.3 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Radical_SAM_N PF08497.5 CDI75031.1 - 6.8 5.5 14.5 7.6 5.3 10.1 1.0 1 0 0 1 1 1 0 Radical SAM N-terminal DUF2347 PF09804.4 CDI75031.1 - 7.2 5.8 14.1 8.9 5.4 9.8 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2347) DUF4407 PF14362.1 CDI75031.1 - 7.9 5.3 25.3 11 4.8 17.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Filo_glycop PF01611.11 CDI75031.1 - 8.5 5.0 13.9 9.3 4.9 9.6 1.0 1 0 0 1 1 1 0 Filovirus glycoprotein ABC2_membrane_2 PF12679.2 CDI75031.1 - 8.7 5.1 7.7 67 2.2 5.3 1.9 1 1 0 1 1 1 0 ABC-2 family transporter protein Exonuc_VII_L PF02601.10 CDI75031.1 - 8.9 5.4 26.5 10 5.1 18.4 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit APG6 PF04111.7 CDI75031.1 - 8.9 5.2 32.2 10 5.0 22.3 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 Asp-B-Hydro_N PF05279.6 CDI75031.1 - 9.1 6.0 18.5 11 5.7 12.8 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Orthopox_A47 PF06334.6 CDI75032.1 - 0.13 11.3 0.1 0.18 10.8 0.0 1.1 1 0 0 1 1 1 0 Orthopoxvirus A47 protein zf-CCHC_4 PF14392.1 CDI75032.1 - 0.23 11.1 0.5 0.39 10.4 0.3 1.3 1 0 0 1 1 1 0 Zinc knuckle Pkinase_Tyr PF07714.12 CDI75034.1 - 0.0045 16.0 0.0 0.0073 15.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 CDI75034.1 - 0.0049 16.0 0.0 0.073 12.2 0.0 2.3 2 1 0 2 2 2 1 Protein kinase domain HEAT_2 PF13646.1 CDI75034.1 - 0.028 14.7 0.4 0.028 14.7 0.3 2.3 2 0 0 2 2 2 0 HEAT repeats V-SNARE_C PF12352.3 CDI75035.1 - 1.9e-12 47.0 0.4 6.7e-12 45.2 0.2 2.0 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.8 CDI75035.1 - 0.0007 19.2 0.1 0.0021 17.7 0.0 1.8 2 0 0 2 2 2 1 Sec20 Peptidase_S8 PF00082.17 CDI75036.1 - 2.1e-43 148.4 0.7 4.1e-43 147.5 0.5 1.4 1 0 0 1 1 1 1 Subtilase family Peptidase_C50 PF03568.12 CDI75036.1 - 0.0071 15.0 0.0 0.015 13.9 0.0 1.4 1 0 0 1 1 1 1 Peptidase family C50 Cu-binding_MopE PF11617.3 CDI75036.1 - 1.4 8.7 5.2 3 7.6 3.6 1.6 1 0 0 1 1 1 0 Protein metal binding site SF-assemblin PF06705.6 CDI75037.1 - 4.4e-33 114.4 17.8 5.7e-33 114.0 12.3 1.1 1 0 0 1 1 1 1 SF-assemblin/beta giardin Ribosomal_L17 PF01196.14 CDI75037.1 - 1.9e-14 53.9 3.2 3.7e-14 53.0 0.0 2.6 1 1 1 2 2 2 1 Ribosomal protein L17 DUF4085 PF13315.1 CDI75037.1 - 0.053 12.8 1.7 0.089 12.1 1.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4085) Baculo_PEP_C PF04513.7 CDI75037.1 - 0.44 10.3 10.5 0.099 12.4 0.4 3.4 2 2 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF3708 PF12501.3 CDI75037.1 - 4.3 7.1 6.5 3.7 7.3 0.5 2.6 2 1 0 2 2 2 0 Phosphate ATP-binding cassette transporter FBPase PF00316.15 CDI75039.1 - 1.2e-65 221.4 0.0 1.4e-65 221.2 0.0 1.0 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase Inositol_P PF00459.20 CDI75039.1 - 0.1 11.8 0.2 0.72 9.1 0.0 2.0 2 0 0 2 2 2 0 Inositol monophosphatase family Peptidase_M24 PF00557.19 CDI75040.1 - 7e-53 179.2 0.0 1e-52 178.7 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 CDI75040.1 - 3.2e-13 49.2 0.0 5.7e-13 48.4 0.0 1.4 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain Ank_2 PF12796.2 CDI75041.1 - 1.4e-06 28.5 0.1 2e-06 28.0 0.1 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 CDI75041.1 - 2.2e-06 27.7 0.1 4.3e-06 26.8 0.0 1.5 1 1 0 1 1 1 1 Ankyrin repeats (many copies) Ank_4 PF13637.1 CDI75041.1 - 4.1e-05 23.9 0.1 0.0052 17.2 0.0 1.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 CDI75041.1 - 0.00012 21.9 0.0 0.16 12.3 0.0 2.7 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.25 CDI75041.1 - 0.014 15.1 0.0 6 6.8 0.0 2.6 3 0 0 3 3 3 0 Ankyrin repeat Peptidase_C48 PF02902.14 CDI75043.1 - 2.1e-19 69.9 0.0 5.1e-19 68.7 0.0 1.6 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain SNF2_N PF00176.18 CDI75044.1 - 2.9e-32 111.6 0.0 2.5e-29 102.0 0.0 2.2 1 1 1 2 2 2 2 SNF2 family N-terminal domain zf-C3HC4_2 PF13923.1 CDI75044.1 - 1.8e-06 27.8 11.4 5.2e-06 26.3 7.9 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CDI75044.1 - 2.6e-06 27.0 8.0 7.8e-06 25.5 5.5 1.9 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 CDI75044.1 - 2.7e-05 23.7 9.5 8.6e-05 22.1 6.6 2.0 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CDI75044.1 - 6.6e-05 22.4 8.6 0.00015 21.3 5.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CDI75044.1 - 0.00014 21.6 11.0 0.00041 20.1 7.6 1.9 1 0 0 1 1 1 1 Ring finger domain Helicase_C PF00271.26 CDI75044.1 - 0.00023 20.9 0.0 0.0032 17.2 0.0 2.5 1 1 0 1 1 1 1 Helicase conserved C-terminal domain UBA_4 PF14555.1 CDI75044.1 - 0.0026 17.2 0.0 0.0074 15.8 0.0 1.8 1 0 0 1 1 1 1 UBA-like domain zf-MIZ PF02891.15 CDI75044.1 - 0.0057 16.1 10.0 0.055 12.9 6.1 2.5 2 0 0 2 2 2 1 MIZ/SP-RING zinc finger zf-RING_6 PF14835.1 CDI75044.1 - 0.14 11.9 4.9 0.53 10.1 3.4 2.0 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-C3HC4_4 PF15227.1 CDI75044.1 - 0.31 10.9 12.0 0.99 9.3 8.3 2.0 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING HEAT PF02985.17 CDI75045.1 - 2.5e-07 30.2 8.2 0.014 15.4 0.1 5.2 4 0 0 4 4 4 3 HEAT repeat HEAT_2 PF13646.1 CDI75045.1 - 0.00058 20.1 0.4 2.2 8.6 0.0 3.7 4 1 0 4 4 4 2 HEAT repeats HEAT_EZ PF13513.1 CDI75045.1 - 0.0018 18.6 5.2 0.18 12.3 0.2 4.0 3 0 0 3 3 3 2 HEAT-like repeat Histone PF00125.19 CDI75046.1 - 2.3e-13 50.0 0.0 3.3e-13 49.5 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 XAP5 PF04921.9 CDI75047.1 - 0.33 10.4 2.2 0.5 9.9 0.0 2.0 2 0 0 2 2 2 0 XAP5, circadian clock regulator Cullin PF00888.17 CDI75048.1 - 9e-107 358.0 4.3 1.3e-106 357.5 3.0 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 CDI75048.1 - 6.5e-24 83.5 0.4 2.3e-23 81.7 0.3 2.0 1 0 0 1 1 1 1 Cullin protein neddylation domain DUF3658 PF12395.3 CDI75048.1 - 0.0074 15.8 0.1 0.018 14.5 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function RE_XamI PF09572.5 CDI75048.1 - 0.027 13.9 0.4 0.064 12.6 0.0 1.9 2 0 0 2 2 2 0 XamI restriction endonuclease DUF4065 PF13274.1 CDI75048.1 - 0.037 14.7 0.1 3.3 8.4 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4065) DUF262 PF03235.9 CDI75049.1 - 0.82 9.5 7.8 0.1 12.5 0.9 2.1 1 1 0 2 2 2 0 Protein of unknown function DUF262 Med11 PF10280.4 CDI75049.1 - 1.9 8.5 12.0 0.18 11.8 2.6 2.3 2 1 0 2 2 2 0 Mediator complex protein PAT1 PF09770.4 CDI75050.1 - 0.46 8.6 52.4 0.63 8.2 36.3 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Macoilin PF09726.4 CDI75050.1 - 0.55 8.4 24.2 0.78 7.9 16.8 1.2 1 0 0 1 1 1 0 Transmembrane protein SprA-related PF12118.3 CDI75050.1 - 0.86 8.8 44.0 1.9 7.7 30.5 1.6 1 0 0 1 1 1 0 SprA-related family Pex14_N PF04695.8 CDI75051.1 - 0.013 15.5 10.4 0.014 15.4 7.2 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region BRF1 PF07741.8 CDI75051.1 - 0.021 15.0 3.9 0.018 15.2 2.7 1.1 1 0 0 1 1 1 0 Brf1-like TBP-binding domain Topoisom_I_N PF02919.10 CDI75051.1 - 0.023 14.0 0.6 0.023 13.9 0.4 1.1 1 0 0 1 1 1 0 Eukaryotic DNA topoisomerase I, DNA binding fragment Flavodoxin_NdrI PF07972.6 CDI75051.1 - 0.08 12.8 2.2 0.092 12.6 1.5 1.2 1 0 0 1 1 1 0 NrdI Flavodoxin like HCV_NS5a_C PF12941.2 CDI75051.1 - 0.082 12.4 0.6 0.086 12.3 0.4 1.0 1 0 0 1 1 1 0 HCV NS5a protein C-terminal region ECH PF00378.15 CDI75051.1 - 0.092 11.8 3.1 0.099 11.7 2.1 1.1 1 0 0 1 1 1 0 Enoyl-CoA hydratase/isomerase family Band_3_cyto PF07565.8 CDI75051.1 - 0.11 11.9 5.8 0.098 12.1 4.1 1.0 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Suf PF05843.9 CDI75051.1 - 0.12 12.0 12.9 0.1 12.2 9.0 1.0 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) EIIBC-GUT_N PF03612.9 CDI75051.1 - 0.14 11.7 7.1 0.16 11.5 4.9 1.1 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus DUF775 PF05603.7 CDI75051.1 - 0.17 11.3 8.2 0.17 11.3 5.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF775) Gti1_Pac2 PF09729.4 CDI75051.1 - 0.19 11.5 2.0 0.18 11.6 1.4 1.1 1 0 0 1 1 1 0 Gti1/Pac2 family Peptidase_S49_N PF08496.5 CDI75051.1 - 0.2 11.4 8.4 0.25 11.1 5.8 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal FAM176 PF14851.1 CDI75051.1 - 0.2 11.2 1.2 0.2 11.3 0.8 1.1 1 0 0 1 1 1 0 FAM176 family Ctr PF04145.10 CDI75051.1 - 0.24 11.4 1.5 0.21 11.5 1.1 1.1 1 0 0 1 1 1 0 Ctr copper transporter family DUF3371 PF11851.3 CDI75051.1 - 0.26 11.9 12.2 0.24 12.1 8.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3371) TFIIA PF03153.8 CDI75051.1 - 0.44 10.3 16.0 0.41 10.4 11.1 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit FLO_LFY PF01698.11 CDI75051.1 - 0.56 9.0 5.7 0.54 9.0 4.0 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein TMEM51 PF15345.1 CDI75051.1 - 0.66 9.6 10.0 0.7 9.5 6.9 1.0 1 0 0 1 1 1 0 Transmembrane protein 51 GRP PF07172.6 CDI75051.1 - 0.92 10.0 5.5 1.1 9.7 3.8 1.2 1 0 0 1 1 1 0 Glycine rich protein family RNA_pol_Rbc25 PF08292.7 CDI75051.1 - 1 9.5 6.5 1.3 9.2 4.5 1.2 1 0 0 1 1 1 0 RNA polymerase III subunit Rpc25 DUF605 PF04652.11 CDI75051.1 - 1.1 8.6 11.0 1 8.6 7.6 1.0 1 0 0 1 1 1 0 Vta1 like Ndc1_Nup PF09531.5 CDI75051.1 - 1.4 7.2 5.0 1.3 7.3 3.4 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup FCP1_C PF09309.5 CDI75051.1 - 1.7 7.8 11.9 2 7.6 8.2 1.1 1 0 0 1 1 1 0 FCP1, C-terminal OATP PF03137.15 CDI75051.1 - 2.2 6.2 7.6 2.3 6.1 5.3 1.0 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family DUF853 PF05872.7 CDI75051.1 - 2.3 6.4 7.9 2.3 6.4 5.5 1.0 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) Kei1 PF08552.6 CDI75051.1 - 2.5 7.7 4.9 2.8 7.5 3.4 1.1 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 UPF0560 PF10577.4 CDI75051.1 - 2.6 6.2 14.7 2.2 6.4 10.2 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Gly_rich PF12810.2 CDI75051.1 - 2.6 7.5 7.3 3.1 7.3 5.0 1.1 1 0 0 1 1 1 0 Glycine rich protein Ilar_coat PF01787.11 CDI75051.1 - 2.7 7.5 6.8 2.8 7.4 4.7 1.1 1 0 0 1 1 1 0 Ilarvirus coat protein DUF1764 PF08576.5 CDI75051.1 - 2.8 8.7 10.8 3.2 8.5 7.5 1.1 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) DUF4407 PF14362.1 CDI75051.1 - 4.1 6.2 12.0 4.5 6.1 8.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Dot_icm_IcmQ PF09475.5 CDI75051.1 - 4.5 6.4 8.7 5.5 6.1 6.0 1.1 1 0 0 1 1 1 0 Dot/Icm secretion system protein (dot_icm_IcmQ) Glyco_transf_15 PF01793.11 CDI75051.1 - 4.6 6.0 8.2 4.8 6.0 5.7 1.0 1 0 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase AIF_C PF14721.1 CDI75051.1 - 4.8 7.4 7.7 5.6 7.2 5.4 1.2 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term DUF4175 PF13779.1 CDI75051.1 - 5.6 4.5 32.8 5.8 4.4 22.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) NARP1 PF12569.3 CDI75051.1 - 5.9 5.5 9.3 6.3 5.4 6.4 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Serinc PF03348.10 CDI75051.1 - 6.3 5.3 9.2 6.3 5.3 6.4 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) DUF3464 PF11947.3 CDI75051.1 - 8.8 5.7 8.0 10 5.5 5.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) DUF912 PF06024.7 CDI75051.1 - 9.2 6.3 9.6 12 6.0 6.7 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Conotoxin PF02950.12 CDI75051.1 - 9.3 7.1 6.6 12 6.7 4.6 1.3 1 0 0 1 1 1 0 Conotoxin DUF3499 PF12005.3 CDI75051.1 - 9.4 6.4 6.7 12 6.0 4.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3499) DDHD PF02862.12 CDI75051.1 - 9.7 5.9 8.4 11 5.6 5.8 1.0 1 0 0 1 1 1 0 DDHD domain ATAD4 PF15321.1 CDI75051.1 - 9.8 7.2 10.1 13 6.8 7.0 1.1 1 0 0 1 1 1 0 ATPase family AAA domain containing 4 EphA2_TM PF14575.1 CDI75051.1 - 9.9 6.6 6.8 18 5.7 4.7 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF4557 PF15101.1 CDI75051.1 - 10 5.9 22.1 12 5.7 15.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) YfhO PF09586.5 CDI75052.1 - 0.0068 14.4 2.4 0.0065 14.5 1.7 1.1 1 0 0 1 1 1 1 Bacterial membrane protein YfhO DUF1453 PF07301.6 CDI75052.1 - 0.0096 15.7 0.1 0.013 15.3 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1453) DUF2615 PF11027.3 CDI75052.1 - 0.016 15.1 0.8 0.034 14.0 0.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2615) DUF3357 PF11837.3 CDI75052.1 - 0.02 14.7 2.6 0.02 14.7 1.8 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF3357) SpoIIIAH PF12685.2 CDI75052.1 - 0.023 14.1 3.1 0.023 14.1 2.2 2.2 2 1 0 2 2 2 0 SpoIIIAH-like protein EphA2_TM PF14575.1 CDI75052.1 - 0.028 14.8 4.0 0.028 14.8 2.8 2.2 1 1 1 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain GRP PF07172.6 CDI75052.1 - 0.03 14.7 2.3 0.03 14.7 1.6 2.1 1 1 1 2 2 2 0 Glycine rich protein family DUF1510 PF07423.6 CDI75052.1 - 0.059 12.7 6.2 0.098 12.0 4.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Conotoxin PF02950.12 CDI75052.1 - 0.059 14.1 6.0 0.059 14.1 4.2 2.8 1 1 1 2 2 2 0 Conotoxin FAM176 PF14851.1 CDI75052.1 - 0.099 12.3 0.9 0.19 11.4 0.6 1.4 1 0 0 1 1 1 0 FAM176 family 7tm_1 PF00001.16 CDI75052.1 - 0.1 11.7 0.3 0.14 11.2 0.2 1.3 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) DUF2339 PF10101.4 CDI75052.1 - 0.14 10.4 9.5 0.2 9.8 6.6 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2339) Med15 PF09606.5 CDI75052.1 - 0.14 10.3 49.3 0.17 10.0 34.2 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Mem_trans PF03547.13 CDI75052.1 - 0.19 9.9 1.1 0.21 9.8 0.8 1.2 1 0 0 1 1 1 0 Membrane transport protein OAD_gamma PF04277.8 CDI75052.1 - 0.46 10.8 0.0 0.46 10.8 0.0 2.5 2 0 0 2 2 1 0 Oxaloacetate decarboxylase, gamma chain Serinc PF03348.10 CDI75052.1 - 0.81 8.3 5.0 1.3 7.6 3.4 1.3 1 0 0 1 1 1 0 Serine incorporator (Serinc) Plant_vir_prot PF01307.12 CDI75052.1 - 0.97 9.1 3.5 1.3 8.8 0.3 2.4 2 1 0 2 2 2 0 Plant viral movement protein Ctr PF04145.10 CDI75052.1 - 1.1 9.2 4.6 0.58 10.1 1.4 1.7 1 1 1 2 2 2 0 Ctr copper transporter family DUF3597 PF12200.3 CDI75052.1 - 1.2 9.5 9.3 0.27 11.6 1.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3597) DUF4131 PF13567.1 CDI75052.1 - 1.2 8.4 9.8 2.7 7.3 6.8 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4131) ODV-E18 PF10717.4 CDI75052.1 - 1.8 8.0 4.3 2 7.8 0.9 2.4 1 1 1 2 2 2 0 Occlusion-derived virus envelope protein ODV-E18 Band_3_cyto PF07565.8 CDI75052.1 - 5 6.5 12.4 7.8 5.9 8.6 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain DUF1345 PF07077.6 CDI75052.1 - 7.9 5.9 10.1 0.81 9.1 1.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1345) Sex_peptide PF08138.6 CDI75052.1 - 8.5 6.3 8.1 0.55 10.1 1.1 2.2 1 1 1 2 2 2 0 Sex peptide (SP) family TMEM154 PF15102.1 CDI75052.1 - 9.8 5.8 16.6 5 6.8 8.4 2.3 2 1 1 3 3 3 0 TMEM154 protein family BAF1_ABF1 PF04684.8 CDI75053.1 - 0.13 11.0 12.5 0.16 10.8 8.7 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor DUF4407 PF14362.1 CDI75053.1 - 1.5 7.6 5.6 1.5 7.7 3.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TMEM51 PF15345.1 CDI75053.1 - 7.9 6.0 19.9 10 5.7 13.8 1.3 1 0 0 1 1 1 0 Transmembrane protein 51 Utp14 PF04615.8 CDI75053.1 - 9.1 4.3 21.7 10 4.1 15.0 1.0 1 0 0 1 1 1 0 Utp14 protein Tyrosinase PF00264.15 CDI75053.1 - 9.4 6.3 12.0 11 6.1 8.3 1.1 1 0 0 1 1 1 0 Common central domain of tyrosinase BSP_II PF05432.6 CDI75055.1 - 0.00019 20.8 10.8 0.00019 20.8 7.5 5.7 3 2 2 6 6 6 1 Bone sialoprotein II (BSP-II) DUF755 PF05501.6 CDI75055.1 - 0.0072 16.3 27.7 0.0072 16.3 19.2 8.4 7 2 1 9 9 9 3 Domain of unknown function (DUF755) DUF1779 PF08680.5 CDI75056.1 - 0.043 13.6 5.4 0.056 13.3 3.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1779) Tyrosinase PF00264.15 CDI75056.1 - 0.077 13.1 2.3 0.09 12.9 1.6 1.2 1 0 0 1 1 1 0 Common central domain of tyrosinase DUF572 PF04502.8 CDI75056.1 - 0.5 9.5 15.3 0.65 9.1 10.6 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Med15 PF09606.5 CDI75056.1 - 0.62 8.1 32.2 0.69 8.0 22.3 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal LCD1 PF09798.4 CDI75056.1 - 1.3 6.9 13.5 1.3 6.9 9.3 1.1 1 0 0 1 1 1 0 DNA damage checkpoint protein Borrelia_P83 PF05262.6 CDI75056.1 - 1.9 6.6 15.2 2.1 6.5 10.5 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein Endonuc_Holl PF10107.4 CDI75056.1 - 2.7 7.6 10.0 3.6 7.2 6.9 1.3 1 0 0 1 1 1 0 Endonuclease related to archaeal Holliday junction resolvase Dala_Dala_lig_N PF01820.16 CDI75056.1 - 3.1 8.1 7.5 4.9 7.5 4.5 1.9 1 1 0 1 1 1 0 D-ala D-ala ligase N-terminus TFIIA PF03153.8 CDI75056.1 - 9 6.0 25.3 11 5.8 17.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CRT10 PF08728.5 CDI75058.1 - 5.8 4.7 6.6 8.2 4.2 4.6 1.1 1 0 0 1 1 1 0 CRT10 Spt20 PF12090.3 CDI75059.1 - 0.0029 16.9 2.2 0.0029 16.9 1.5 3.3 2 1 0 2 2 2 1 Spt20 family FimP PF09766.4 CDI75059.1 - 0.0029 16.7 8.2 0.0029 16.7 5.7 2.5 2 1 0 2 2 2 1 Fms-interacting protein Glyco_transf_8 PF01501.15 CDI75059.1 - 0.21 10.8 0.1 0.21 10.8 0.1 2.2 2 0 0 2 2 2 0 Glycosyl transferase family 8 UPF0233 PF06781.7 CDI75059.1 - 0.4 10.3 0.0 0.4 10.3 0.0 3.7 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0233) Yos1 PF08571.5 CDI75059.1 - 0.41 10.7 0.0 0.41 10.7 0.0 2.4 2 1 0 2 2 2 0 Yos1-like TT_ORF1 PF02956.9 CDI75059.1 - 1.1 7.6 17.5 1.3 7.3 0.9 2.1 2 0 0 2 2 2 0 TT viral orf 1 Dynamin_N PF00350.18 CDI75059.1 - 2 8.2 14.0 1.5 8.6 0.7 2.4 2 0 0 2 2 2 0 Dynamin family Zip PF02535.17 CDI75059.1 - 4.8 6.0 21.7 0.065 12.2 1.0 2.2 2 0 0 2 2 2 0 ZIP Zinc transporter YjgP_YjgQ PF03739.9 CDI75059.1 - 8.6 4.9 10.0 6.5 5.3 3.1 2.1 2 0 0 2 2 2 0 Predicted permease YjgP/YjgQ family Drc1-Sld2 PF11719.3 CDI75061.1 - 1.8 7.5 28.6 2.2 7.2 19.8 1.0 1 0 0 1 1 1 0 DNA replication and checkpoint protein Adaptin_binding PF10199.4 CDI75062.1 - 0.76 10.0 0.0 0.76 10.0 0.0 10.1 6 5 0 6 6 6 0 Alpha and gamma adaptin binding protein p34 NAD_binding_8 PF13450.1 CDI75064.1 - 7.2e-09 35.5 2.2 8.7e-08 32.0 1.5 3.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 CDI75064.1 - 7e-05 23.1 3.0 0.00018 21.8 2.1 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 CDI75064.1 - 0.0023 17.8 0.3 0.0023 17.8 0.2 4.5 5 0 0 5 5 5 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 CDI75064.1 - 0.055 12.5 2.1 0.14 11.2 1.5 1.6 1 0 0 1 1 1 0 Thi4 family hDGE_amylase PF14701.1 CDI75065.1 - 2.6e-11 43.0 0.0 1.1e-10 41.0 0.0 1.9 2 0 0 2 2 2 1 glucanotransferase domain of human glycogen debranching enzyme HGD-D PF06050.8 CDI75065.1 - 0.15 10.8 0.0 0.19 10.4 0.0 1.1 1 0 0 1 1 1 0 2-hydroxyglutaryl-CoA dehydratase, D-component Ribosomal_60s PF00428.14 CDI75065.1 - 0.36 11.2 9.2 0.48 10.8 5.4 1.8 2 0 0 2 2 2 0 60s Acidic ribosomal protein BAF1_ABF1 PF04684.8 CDI75065.1 - 1.6 7.5 18.6 0.14 10.9 5.1 2.2 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor Oest_recep PF02159.10 CDI75065.1 - 2.6 8.1 8.1 0.81 9.8 2.1 2.0 2 0 0 2 2 2 0 Oestrogen receptor Androgen_recep PF02166.11 CDI75065.1 - 2.8 6.6 12.8 0.2 10.4 5.2 1.6 2 0 0 2 2 2 0 Androgen receptor FimP PF09766.4 CDI75066.1 - 0.0026 16.9 24.7 0.003 16.6 17.1 1.1 1 0 0 1 1 1 1 Fms-interacting protein PBP1_TM PF14812.1 CDI75066.1 - 0.016 15.4 3.3 0.019 15.2 2.3 1.2 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal NHS PF15273.1 CDI75066.1 - 0.04 12.5 14.5 0.048 12.3 10.1 1.0 1 0 0 1 1 1 0 NHS-like HA2 PF04408.18 CDI75066.1 - 0.05 13.6 4.9 0.072 13.1 3.4 1.3 1 0 0 1 1 1 0 Helicase associated domain (HA2) ADP_ribosyl_GH PF03747.9 CDI75066.1 - 0.068 12.9 3.3 0.072 12.8 2.3 1.0 1 0 0 1 1 1 0 ADP-ribosylglycohydrolase Dala_Dala_lig_N PF01820.16 CDI75066.1 - 0.073 13.3 8.2 0.088 13.1 5.7 1.1 1 0 0 1 1 1 0 D-ala D-ala ligase N-terminus DUF3987 PF13148.1 CDI75066.1 - 0.1 11.1 11.3 0.12 10.8 7.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) Vfa1 PF08432.5 CDI75066.1 - 0.11 12.4 17.4 0.14 12.2 12.0 1.0 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 SprA-related PF12118.3 CDI75066.1 - 0.14 11.4 41.9 0.17 11.1 29.0 1.1 1 0 0 1 1 1 0 SprA-related family MRP-S31 PF15433.1 CDI75066.1 - 0.17 11.3 17.8 0.19 11.1 12.3 1.1 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 RR_TM4-6 PF06459.7 CDI75066.1 - 0.18 11.6 15.5 0.19 11.5 10.8 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 MARCKS PF02063.12 CDI75066.1 - 0.19 11.5 8.4 0.21 11.4 5.8 1.0 1 0 0 1 1 1 0 MARCKS family Serinc PF03348.10 CDI75066.1 - 0.19 10.3 13.3 0.24 10.0 9.2 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) HK PF02110.10 CDI75066.1 - 0.22 10.6 3.5 0.19 10.8 1.8 1.3 1 1 0 1 1 1 0 Hydroxyethylthiazole kinase family Zip PF02535.17 CDI75066.1 - 0.22 10.4 3.4 0.22 10.5 2.4 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter FAM60A PF15396.1 CDI75066.1 - 0.22 11.2 12.8 0.27 10.9 8.9 1.1 1 0 0 1 1 1 0 Protein Family FAM60A OATP PF03137.15 CDI75066.1 - 0.26 9.2 11.3 0.26 9.3 7.8 1.2 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Raftlin PF15250.1 CDI75066.1 - 0.26 9.7 15.7 0.3 9.5 10.9 1.0 1 0 0 1 1 1 0 Raftlin Usp PF00582.21 CDI75066.1 - 0.28 11.3 2.3 0.35 11.0 1.6 1.1 1 0 0 1 1 1 0 Universal stress protein family DDHD PF02862.12 CDI75066.1 - 0.34 10.6 16.2 0.37 10.5 11.2 1.1 1 0 0 1 1 1 0 DDHD domain SpoVR PF04293.8 CDI75066.1 - 0.36 9.1 14.6 0.41 8.9 10.1 1.0 1 0 0 1 1 1 0 SpoVR like protein IPP-2 PF04979.9 CDI75066.1 - 0.4 10.9 12.0 0.53 10.5 8.3 1.1 1 0 0 1 1 1 0 Protein phosphatase inhibitor 2 (IPP-2) Rtf2 PF04641.7 CDI75066.1 - 0.4 9.8 16.3 0.45 9.6 11.3 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger FPN1 PF06963.7 CDI75066.1 - 0.4 8.9 8.1 0.47 8.7 5.6 1.1 1 0 0 1 1 1 0 Ferroportin1 (FPN1) SeqA PF03925.8 CDI75066.1 - 0.41 10.3 13.1 0.55 9.9 9.1 1.3 1 0 0 1 1 1 0 SeqA protein Tim54 PF11711.3 CDI75066.1 - 0.42 9.1 10.1 0.47 8.9 7.0 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DUF913 PF06025.7 CDI75066.1 - 0.43 9.2 9.9 0.45 9.2 6.9 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Peptidase_S49_N PF08496.5 CDI75066.1 - 0.45 10.3 15.8 0.55 10.0 10.9 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF4011 PF13195.1 CDI75066.1 - 0.45 10.5 9.3 0.48 10.4 6.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4011) RP-C_C PF11800.3 CDI75066.1 - 0.45 10.1 14.1 0.49 10.0 9.8 1.2 1 0 0 1 1 1 0 Replication protein C C-terminal region CCDC71L PF15374.1 CDI75066.1 - 0.46 9.7 17.6 0.51 9.6 12.2 1.0 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 71L SelP_N PF04592.9 CDI75066.1 - 0.5 9.7 12.8 0.58 9.4 8.8 1.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region DUF3408 PF11888.3 CDI75066.1 - 0.54 10.1 13.4 0.64 9.9 9.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) Folate_carrier PF01770.13 CDI75066.1 - 0.58 8.6 10.7 0.63 8.4 7.4 1.1 1 0 0 1 1 1 0 Reduced folate carrier Cas1_AcylT PF07779.7 CDI75066.1 - 0.6 8.5 7.2 0.65 8.3 5.0 1.0 1 0 0 1 1 1 0 10 TM Acyl Transferase domain found in Cas1p SR-25 PF10500.4 CDI75066.1 - 0.63 9.4 15.4 0.83 9.0 10.7 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein SUFU_C PF12470.3 CDI75066.1 - 0.65 9.5 8.9 0.78 9.2 6.2 1.1 1 0 0 1 1 1 0 Suppressor of Fused Gli/Ci N terminal binding domain DUF2048 PF09752.4 CDI75066.1 - 0.66 8.7 8.6 0.74 8.6 6.0 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2048) Gti1_Pac2 PF09729.4 CDI75066.1 - 0.72 9.7 9.9 0.86 9.4 6.9 1.2 1 0 0 1 1 1 0 Gti1/Pac2 family SpoIIP PF07454.6 CDI75066.1 - 0.73 8.9 14.4 0.81 8.7 10.0 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Rhabdo_ncap PF00945.13 CDI75066.1 - 0.74 8.3 8.2 0.9 8.0 5.7 1.0 1 0 0 1 1 1 0 Rhabdovirus nucleocapsid protein Pal1 PF08316.6 CDI75066.1 - 0.79 10.1 9.5 0.95 9.9 6.6 1.2 1 0 0 1 1 1 0 Pal1 cell morphology protein DUF2052 PF09747.4 CDI75066.1 - 0.83 9.5 22.3 0.94 9.3 15.5 1.1 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) DUF1510 PF07423.6 CDI75066.1 - 0.98 8.7 19.1 1.1 8.5 13.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) CDC45 PF02724.9 CDI75066.1 - 1 7.3 15.2 1.1 7.2 10.5 1.0 1 0 0 1 1 1 0 CDC45-like protein RNase_H2-Ydr279 PF09468.5 CDI75066.1 - 1.1 8.3 9.5 1.1 8.3 6.6 1.0 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) CKAP2_C PF15297.1 CDI75066.1 - 1.1 7.9 19.0 1.3 7.7 13.2 1.0 1 0 0 1 1 1 0 Cytoskeleton-associated protein 2 C-terminus PPP4R2 PF09184.6 CDI75066.1 - 1.2 8.6 15.1 1.4 8.4 10.5 1.0 1 0 0 1 1 1 0 PPP4R2 FHIPEP PF00771.15 CDI75066.1 - 1.2 7.3 10.2 1.5 7.0 7.1 1.2 1 0 0 1 1 1 0 FHIPEP family DHHW PF14286.1 CDI75066.1 - 1.3 8.3 13.8 1.3 8.2 9.5 1.0 1 0 0 1 1 1 0 DHHW protein DUF1764 PF08576.5 CDI75066.1 - 1.3 9.8 22.4 2 9.2 15.5 1.3 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) DUF4557 PF15101.1 CDI75066.1 - 1.3 8.7 28.9 1.6 8.5 20.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) Cytochrom_NNT PF03264.9 CDI75066.1 - 1.4 8.3 12.6 1.9 7.8 8.7 1.2 1 0 0 1 1 1 0 NapC/NirT cytochrome c family, N-terminal region CPSF100_C PF13299.1 CDI75066.1 - 1.4 9.1 14.0 1.6 8.9 9.7 1.1 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Spc7_N PF15402.1 CDI75066.1 - 1.4 6.8 16.6 1.5 6.7 11.5 1.1 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 AAA_11 PF13086.1 CDI75066.1 - 1.5 8.3 18.2 1.7 8.1 12.6 1.0 1 0 0 1 1 1 0 AAA domain RtcB PF01139.12 CDI75066.1 - 1.5 7.7 11.1 1.7 7.5 7.7 1.0 1 0 0 1 1 1 0 tRNA-splicing ligase RtcB DUF3449 PF11931.3 CDI75066.1 - 1.6 8.2 17.0 1.8 8.0 11.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3449) CobT PF06213.7 CDI75066.1 - 1.6 7.8 18.0 1.9 7.5 12.5 1.0 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF2347 PF09804.4 CDI75066.1 - 1.6 7.9 11.2 1.7 7.8 7.8 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2347) Cellulose_synt PF03552.9 CDI75066.1 - 1.7 6.8 9.8 1.8 6.7 6.8 1.0 1 0 0 1 1 1 0 Cellulose synthase Shisa PF13908.1 CDI75066.1 - 1.7 8.8 21.0 2.2 8.4 14.6 1.1 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Folliculin PF11704.3 CDI75066.1 - 1.8 8.1 11.0 2.4 7.6 7.6 1.3 1 0 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport DUF4045 PF13254.1 CDI75066.1 - 1.8 7.7 16.1 2 7.6 11.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Chorismate_synt PF01264.16 CDI75066.1 - 1.8 6.9 6.0 2 6.8 4.1 1.0 1 0 0 1 1 1 0 Chorismate synthase DDRGK PF09756.4 CDI75066.1 - 1.9 7.8 25.3 2.3 7.5 17.6 1.1 1 0 0 1 1 1 0 DDRGK domain FixO PF02433.10 CDI75066.1 - 2 7.7 9.4 2.4 7.4 6.5 1.1 1 0 0 1 1 1 0 Cytochrome C oxidase, mono-heme subunit/FixO SID-1_RNA_chan PF13965.1 CDI75066.1 - 2 6.4 11.9 2.4 6.2 8.3 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DUF3260 PF11658.3 CDI75066.1 - 2.1 6.3 14.8 2.4 6.1 10.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3260) PAT1 PF09770.4 CDI75066.1 - 2.1 6.4 40.9 2.4 6.3 28.4 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 RNA_pol_Rpb1_5 PF04998.12 CDI75066.1 - 2.4 7.3 9.9 2.6 7.2 6.8 1.1 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 U1snRNP70_N PF12220.3 CDI75066.1 - 2.4 8.5 22.8 3.3 8.1 15.8 1.2 1 0 0 1 1 1 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal HCO3_cotransp PF00955.16 CDI75066.1 - 2.4 6.7 6.8 2.5 6.6 4.7 1.1 1 0 0 1 1 1 0 HCO3- transporter family DUF3464 PF11947.3 CDI75066.1 - 2.5 7.5 12.8 3.5 7.0 8.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) Baculo_PP31 PF05311.6 CDI75066.1 - 2.5 7.2 16.5 3 7.0 11.4 1.1 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) Ycf1 PF05758.7 CDI75066.1 - 2.7 5.5 17.7 2.9 5.4 12.2 1.0 1 0 0 1 1 1 0 Ycf1 SAGA-Tad1 PF12767.2 CDI75066.1 - 2.7 7.5 20.7 3.8 7.1 14.3 1.3 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit DUF1980 PF09323.5 CDI75066.1 - 2.8 7.6 14.3 3 7.5 9.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) BORG_CEP PF14957.1 CDI75066.1 - 2.8 8.8 11.7 3.5 8.5 8.1 1.2 1 0 0 1 1 1 0 Cdc42 effector AUX_IAA PF02309.11 CDI75066.1 - 2.9 7.5 17.1 3.3 7.3 11.8 1.0 1 0 0 1 1 1 0 AUX/IAA family Spore_coat_CotO PF14153.1 CDI75066.1 - 2.9 7.2 27.7 3.5 7.0 19.2 1.1 1 0 0 1 1 1 0 Spore coat protein CotO FAM91_C PF14648.1 CDI75066.1 - 3 6.5 10.6 3.4 6.4 7.3 1.0 1 0 0 1 1 1 0 FAM91 C-terminus DUF2201_N PF13203.1 CDI75066.1 - 3 6.9 16.2 3.5 6.7 11.2 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain GAGA_bind PF06217.7 CDI75066.1 - 3.1 7.6 16.7 3.6 7.4 11.6 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family eIF-3_zeta PF05091.7 CDI75066.1 - 3.4 6.1 20.4 3.6 6.1 14.2 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF853 PF05872.7 CDI75066.1 - 3.4 5.9 13.6 3.9 5.7 9.4 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) NARP1 PF12569.3 CDI75066.1 - 3.4 6.3 19.3 4 6.0 13.4 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 CRF1 PF10380.4 CDI75066.1 - 3.4 8.0 12.1 4.4 7.6 8.4 1.3 1 0 0 1 1 1 0 Transcription factor CRF1 BTV_NS2 PF04514.7 CDI75066.1 - 3.4 6.4 14.6 3.7 6.3 10.1 1.0 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 FNIP_N PF14636.1 CDI75066.1 - 3.7 8.0 16.1 4.8 7.6 11.2 1.2 1 0 0 1 1 1 0 Folliculin-interacting protein N-terminus FLO_LFY PF01698.11 CDI75066.1 - 3.7 6.2 18.0 4.2 6.1 12.5 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein PA26 PF04636.8 CDI75066.1 - 3.9 6.0 13.2 4.2 5.9 9.2 1.0 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Gag_spuma PF03276.9 CDI75066.1 - 3.9 5.6 30.8 4 5.6 21.4 1.0 1 0 0 1 1 1 0 Spumavirus gag protein DUF763 PF05559.6 CDI75066.1 - 4.4 6.1 10.1 5.3 5.8 7.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF763) DUF844 PF05815.6 CDI75066.1 - 4.5 6.0 16.9 5.4 5.7 11.7 1.0 1 0 0 1 1 1 0 Baculovirus protein of unknown function (DUF844) 7tm_7 PF08395.7 CDI75066.1 - 4.5 6.1 11.7 5.7 5.8 8.1 1.2 1 0 0 1 1 1 0 7tm Chemosensory receptor Inhibitor_I71 PF12628.2 CDI75066.1 - 4.6 6.8 8.3 5.2 6.6 5.7 1.1 1 0 0 1 1 1 0 Falstatin, cysteine peptidase inhibitor Peptidase_U57 PF05582.7 CDI75066.1 - 4.8 6.0 13.6 5.5 5.8 9.4 1.1 1 0 0 1 1 1 0 YabG peptidase U57 Asp-B-Hydro_N PF05279.6 CDI75066.1 - 5 6.8 14.7 5.6 6.7 10.2 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Plasmodium_Vir PF05795.6 CDI75066.1 - 5.1 6.2 8.2 5.2 6.1 5.7 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Paf1 PF03985.8 CDI75066.1 - 5.3 5.6 22.5 6.4 5.3 15.6 1.2 1 0 0 1 1 1 0 Paf1 DUF2813 PF11398.3 CDI75066.1 - 5.5 5.9 17.9 5.8 5.8 12.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2813) Herpes_env PF01673.13 CDI75066.1 - 5.6 5.4 16.7 6.7 5.1 11.6 1.0 1 0 0 1 1 1 0 Herpesvirus putative major envelope glycoprotein YABBY PF04690.8 CDI75066.1 - 6 7.0 13.0 7.2 6.8 9.0 1.1 1 0 0 1 1 1 0 YABBY protein PCEMA1 PF07418.6 CDI75066.1 - 6.3 6.0 10.8 7.1 5.9 7.5 1.1 1 0 0 1 1 1 0 Acidic phosphoprotein precursor PCEMA1 Peptidase_S15 PF02129.13 CDI75066.1 - 6.9 6.0 12.8 8.2 5.7 8.8 1.1 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Herpes_DNAp_acc PF04929.7 CDI75066.1 - 8 5.3 13.7 8.6 5.2 9.5 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor DUF4220 PF13968.1 CDI75066.1 - 8 5.4 9.5 8.7 5.3 6.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4220) Anoctamin PF04547.7 CDI75066.1 - 8.1 4.9 17.3 8.9 4.8 12.0 1.0 1 0 0 1 1 1 0 Calcium-activated chloride channel TraH_2 PF06871.6 CDI75066.1 - 8.1 5.8 8.3 9.2 5.6 5.7 1.2 1 0 0 1 1 1 0 TraH_2 Glyco_transf_15 PF01793.11 CDI75066.1 - 8.6 5.1 16.1 10 4.9 11.2 1.1 1 0 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase DUF1800 PF08811.6 CDI75066.1 - 9.3 5.0 24.7 11 4.8 17.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1800) Band_3_cyto PF07565.8 CDI75066.1 - 9.6 5.6 19.8 11 5.3 13.7 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain ATP-synt_B PF00430.13 CDI75068.1 - 8.3 6.2 16.2 0.6 9.9 5.5 2.3 1 1 1 2 2 2 0 ATP synthase B/B' CF(0) DUF4207 PF13904.1 CDI75069.1 - 2.2e-05 23.9 23.9 2.2e-05 23.9 16.6 10.8 7 5 3 10 10 10 1 Domain of unknown function (DUF4207) Mucin PF01456.12 CDI75071.1 - 0.017 14.9 0.6 0.017 14.9 0.4 6.8 6 2 1 7 7 7 0 Mucin-like glycoprotein DUF1510 PF07423.6 CDI75072.1 - 0.0013 18.1 5.4 0.0016 17.8 3.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) TRAP_alpha PF03896.11 CDI75072.1 - 0.0013 17.8 1.2 0.0014 17.7 0.9 1.1 1 0 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit DivIC PF04977.10 CDI75072.1 - 0.0017 17.8 12.3 0.0027 17.1 8.6 1.3 1 0 0 1 1 1 1 Septum formation initiator RskA PF10099.4 CDI75072.1 - 0.0019 17.9 1.3 0.0022 17.7 0.9 1.0 1 0 0 1 1 1 1 Anti-sigma-K factor rskA Protocadherin PF08374.6 CDI75072.1 - 0.0055 16.3 2.2 0.0056 16.3 1.6 1.1 1 0 0 1 1 1 1 Protocadherin SpoIIIAH PF12685.2 CDI75072.1 - 0.0062 16.0 2.9 0.0067 15.9 2.0 1.1 1 0 0 1 1 1 1 SpoIIIAH-like protein Nucleoside_tran PF01733.13 CDI75072.1 - 0.0068 15.6 3.2 0.0066 15.6 2.2 1.0 1 0 0 1 1 1 1 Nucleoside transporter EphA2_TM PF14575.1 CDI75072.1 - 0.0073 16.6 2.9 0.011 16.0 2.0 1.4 1 1 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain FAM176 PF14851.1 CDI75072.1 - 0.01 15.4 1.6 0.012 15.3 1.1 1.1 1 0 0 1 1 1 0 FAM176 family DUF2514 PF10721.4 CDI75072.1 - 0.012 15.3 6.7 0.014 15.1 4.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) RAB3GAP2_N PF14655.1 CDI75072.1 - 0.015 14.3 3.7 0.017 14.1 2.5 1.1 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus DUF2149 PF09919.4 CDI75072.1 - 0.022 14.8 3.5 0.03 14.4 2.4 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2149) HGTP_anticodon2 PF12745.2 CDI75072.1 - 0.033 13.3 4.9 0.038 13.1 3.4 1.1 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs Serinc PF03348.10 CDI75072.1 - 0.037 12.7 1.9 0.039 12.6 1.3 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) Ctr PF04145.10 CDI75072.1 - 0.039 14.0 0.7 0.042 13.8 0.5 1.1 1 0 0 1 1 1 0 Ctr copper transporter family PigN PF04987.9 CDI75072.1 - 0.044 12.4 0.3 0.056 12.0 0.2 1.0 1 0 0 1 1 1 0 Phosphatidylinositolglycan class N (PIG-N) Conotoxin PF02950.12 CDI75072.1 - 0.045 14.5 6.8 0.31 11.8 4.7 2.2 1 1 0 1 1 1 0 Conotoxin Mem_trans PF03547.13 CDI75072.1 - 0.049 11.9 1.9 0.048 11.9 1.3 1.0 1 0 0 1 1 1 0 Membrane transport protein Endonuc_Holl PF10107.4 CDI75072.1 - 0.054 13.1 7.3 0.056 13.1 5.1 1.2 1 0 0 1 1 1 0 Endonuclease related to archaeal Holliday junction resolvase VID27 PF08553.5 CDI75072.1 - 0.08 11.1 5.5 0.082 11.1 3.8 1.0 1 0 0 1 1 1 0 VID27 cytoplasmic protein DUF3357 PF11837.3 CDI75072.1 - 0.083 12.7 0.4 0.13 12.1 0.3 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF3357) GPCR_chapero_1 PF11904.3 CDI75072.1 - 0.099 11.7 4.2 0.11 11.6 2.9 1.0 1 0 0 1 1 1 0 GPCR-chaperone DUF3260 PF11658.3 CDI75072.1 - 0.1 10.7 3.3 0.11 10.6 2.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3260) FHIPEP PF00771.15 CDI75072.1 - 0.12 10.6 2.0 0.11 10.7 1.4 1.1 1 0 0 1 1 1 0 FHIPEP family SHR3_chaperone PF08229.6 CDI75072.1 - 0.13 11.2 9.7 0.17 10.8 6.7 1.2 1 0 0 1 1 1 0 ER membrane protein SH3 ExbD PF02472.11 CDI75072.1 - 0.14 12.2 2.7 0.17 11.8 1.8 1.2 1 0 0 1 1 1 0 Biopolymer transport protein ExbD/TolR DUF4006 PF13179.1 CDI75072.1 - 0.14 11.6 4.1 0.26 10.8 2.9 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF4006) IncA PF04156.9 CDI75072.1 - 0.16 11.5 11.2 0.19 11.3 7.8 1.2 1 0 0 1 1 1 0 IncA protein GLTP PF08718.6 CDI75072.1 - 0.19 11.7 2.3 0.22 11.5 1.6 1.1 1 0 0 1 1 1 0 Glycolipid transfer protein (GLTP) TMEM154 PF15102.1 CDI75072.1 - 0.2 11.3 6.4 0.45 10.2 4.0 1.7 1 1 1 2 2 2 0 TMEM154 protein family DUF808 PF05661.7 CDI75072.1 - 0.21 10.4 2.2 0.23 10.2 1.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF808) TMEM51 PF15345.1 CDI75072.1 - 0.21 11.2 4.2 0.22 11.2 2.9 1.1 1 0 0 1 1 1 0 Transmembrane protein 51 Sporozoite_P67 PF05642.6 CDI75072.1 - 0.23 9.2 2.5 0.28 9.0 1.7 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF2681 PF10883.3 CDI75072.1 - 0.25 11.5 12.2 0.38 10.9 8.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) Folate_carrier PF01770.13 CDI75072.1 - 0.27 9.6 1.1 0.31 9.5 0.7 1.2 1 0 0 1 1 1 0 Reduced folate carrier DUF4637 PF15470.1 CDI75072.1 - 0.28 10.7 5.5 0.35 10.4 3.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) YfhO PF09586.5 CDI75072.1 - 0.29 9.1 1.3 0.3 9.0 0.9 1.0 1 0 0 1 1 1 0 Bacterial membrane protein YfhO Med15 PF09606.5 CDI75072.1 - 0.3 9.2 16.2 0.32 9.1 11.3 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Glyco_transf_15 PF01793.11 CDI75072.1 - 0.3 9.9 4.8 0.34 9.8 3.3 1.0 1 0 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase K_trans PF02705.11 CDI75072.1 - 0.34 9.2 1.4 0.34 9.2 1.0 1.0 1 0 0 1 1 1 0 K+ potassium transporter DUF4199 PF13858.1 CDI75072.1 - 0.35 10.7 2.0 0.43 10.4 1.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) EIIBC-GUT_N PF03612.9 CDI75072.1 - 0.36 10.4 3.5 0.45 10.1 2.4 1.1 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus CIAPIN1 PF05093.8 CDI75072.1 - 0.37 10.8 3.5 0.73 9.9 2.4 1.5 1 1 0 1 1 1 0 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis GspL_C PF12693.2 CDI75072.1 - 0.38 10.5 11.5 0.51 10.0 8.0 1.3 1 1 0 1 1 1 0 GspL periplasmic domain DUF2828 PF11443.3 CDI75072.1 - 0.39 8.8 4.4 0.39 8.8 3.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) DUF1266 PF06889.6 CDI75072.1 - 0.4 10.4 4.0 0.48 10.1 2.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1266) DUF1980 PF09323.5 CDI75072.1 - 0.43 10.3 2.7 0.54 9.9 1.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) SID-1_RNA_chan PF13965.1 CDI75072.1 - 0.63 8.1 3.5 0.6 8.1 2.4 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 OSTbeta PF15048.1 CDI75072.1 - 0.71 9.9 8.3 0.85 9.7 5.7 1.3 1 1 0 1 1 1 0 Organic solute transporter subunit beta protein FPN1 PF06963.7 CDI75072.1 - 0.77 8.0 2.6 0.8 8.0 1.8 1.1 1 0 0 1 1 1 0 Ferroportin1 (FPN1) Dynamin_N PF00350.18 CDI75072.1 - 0.77 9.5 4.3 0.84 9.4 3.0 1.1 1 0 0 1 1 1 0 Dynamin family OAD_gamma PF04277.8 CDI75072.1 - 0.82 10.0 3.8 1.2 9.5 2.7 1.4 1 1 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain WBP-1 PF11669.3 CDI75072.1 - 0.86 9.7 3.8 1.3 9.1 2.6 1.5 1 1 0 1 1 1 0 WW domain-binding protein 1 DDHD PF02862.12 CDI75072.1 - 0.95 9.2 5.8 1 9.1 4.0 1.1 1 0 0 1 1 1 0 DDHD domain Bap31 PF05529.7 CDI75072.1 - 1.1 8.7 7.1 1.2 8.5 4.9 1.1 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like Bud13 PF09736.4 CDI75072.1 - 1.1 9.5 11.9 1.2 9.3 8.2 1.1 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex Prog_receptor PF02161.10 CDI75072.1 - 1.3 7.7 6.0 1.4 7.6 4.1 1.0 1 0 0 1 1 1 0 Progesterone receptor Ly49 PF08391.5 CDI75072.1 - 2.2 8.4 12.2 4.1 7.5 8.5 1.4 1 1 0 1 1 1 0 Ly49-like protein, N-terminal region GRP PF07172.6 CDI75072.1 - 2.4 8.6 4.8 3.3 8.2 3.1 1.4 1 1 0 1 1 1 0 Glycine rich protein family DUF4557 PF15101.1 CDI75072.1 - 2.6 7.8 10.4 2.8 7.7 7.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) DUF3381 PF11861.3 CDI75072.1 - 3.8 6.9 14.9 5.1 6.5 10.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) Ycf1 PF05758.7 CDI75072.1 - 3.9 5.0 10.8 4.1 5.0 7.5 1.0 1 0 0 1 1 1 0 Ycf1 Baculo_11_kDa PF06143.6 CDI75072.1 - 6.4 6.2 7.4 0.73 9.2 1.6 2.0 1 1 1 2 2 2 0 Baculovirus 11 kDa family Activator_LAG-3 PF11498.3 CDI75072.1 - 8 5.0 22.6 9 4.9 15.7 1.0 1 0 0 1 1 1 0 Transcriptional activator LAG-3 DUF4175 PF13779.1 CDI75072.1 - 9.2 3.8 18.8 10 3.6 13.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) MIP-T3 PF10243.4 CDI75075.1 - 0.33 9.3 49.5 0.37 9.1 34.3 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 IncA PF04156.9 CDI75075.1 - 0.53 9.8 32.1 1.3 8.5 22.2 1.6 1 1 0 1 1 1 0 IncA protein VIT1 PF01988.14 CDI75075.1 - 0.88 9.0 5.2 1.5 8.2 3.6 1.5 1 0 0 1 1 1 0 VIT family PAT1 PF09770.4 CDI75075.1 - 8.9 4.4 60.7 9.6 4.2 42.1 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DDRGK PF09756.4 CDI75076.1 - 9.9 5.5 30.6 3.6 6.9 13.2 2.2 2 0 0 2 2 2 0 DDRGK domain Med15 PF09606.5 CDI75077.1 - 1.4 6.9 275.8 0.31 9.2 63.9 2.7 2 1 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF1510 PF07423.6 CDI75080.1 - 0.89 8.8 64.3 0.012 15.0 31.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1510) Claudin_2 PF13903.1 CDI75081.1 - 0.011 15.4 3.9 0.011 15.4 2.7 1.9 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction TPP_enzyme_N PF02776.13 CDI75081.1 - 0.016 14.6 10.0 0.016 14.6 7.0 2.0 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain Hamartin PF04388.7 CDI75081.1 - 0.25 9.9 11.2 0.27 9.8 7.8 1.0 1 0 0 1 1 1 0 Hamartin protein C6 PF01681.12 CDI75081.1 - 0.4 10.7 9.6 0.51 10.4 3.6 2.1 2 0 0 2 2 2 0 C6 domain TFIIA PF03153.8 CDI75081.1 - 6.2 6.6 23.3 7.4 6.3 16.1 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF2232 PF09991.4 CDI75081.1 - 8.4 5.2 7.3 1.2 8.0 2.5 1.4 2 0 0 2 2 2 0 Predicted membrane protein (DUF2232) DUF3446 PF11928.3 CDI75081.1 - 8.6 6.6 9.6 13 6.0 1.3 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3446) PT PF04886.7 CDI75082.1 - 3.6e-12 45.3 21.4 4e-05 22.8 2.0 4.1 1 1 2 3 3 3 3 PT repeat UbiA PF01040.13 CDI75082.1 - 2e-07 30.5 0.0 2e-07 30.5 0.0 2.0 2 0 0 2 2 2 1 UbiA prenyltransferase family SR-25 PF10500.4 CDI75082.1 - 9.6e-06 25.2 20.9 9.6e-06 25.2 14.5 3.0 2 1 0 2 2 2 1 Nuclear RNA-splicing-associated protein Med15 PF09606.5 CDI75082.1 - 7e-05 21.2 19.6 7e-05 21.2 13.6 2.5 3 0 0 3 3 3 1 ARC105 or Med15 subunit of Mediator complex non-fungal DUF605 PF04652.11 CDI75082.1 - 0.00079 18.9 15.4 0.00079 18.9 10.7 3.5 3 1 0 3 3 3 1 Vta1 like ETRAMP PF09716.5 CDI75082.1 - 0.013 15.4 9.0 0.62 10.0 0.1 3.0 1 1 1 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) Macoilin PF09726.4 CDI75082.1 - 0.44 8.7 43.4 0.64 8.2 30.1 1.1 1 0 0 1 1 1 0 Transmembrane protein Dus PF01207.12 CDI75083.1 - 2.9e-58 197.1 0.0 1.7e-51 174.8 0.0 2.0 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) BTB PF00651.26 CDI75084.1 - 7e-07 29.2 0.1 2.2e-06 27.5 0.0 1.8 1 1 1 2 2 2 1 BTB/POZ domain CLTH PF10607.4 CDI75085.1 - 3.1e-14 52.8 0.0 5.5e-14 52.0 0.0 1.3 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain DUF2422 PF10337.4 CDI75089.1 - 0.14 10.8 0.0 0.25 10.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2422) Chordopox_A33R PF05966.7 CDI75089.1 - 0.24 10.1 0.2 0.46 9.2 0.2 1.4 1 0 0 1 1 1 0 Chordopoxvirus A33R protein AAA_11 PF13086.1 CDI75091.1 - 0.0033 17.0 0.8 0.0033 17.0 0.5 2.3 2 0 0 2 2 2 1 AAA domain SAGA-Tad1 PF12767.2 CDI75091.1 - 0.0052 16.4 25.8 0.029 14.0 5.0 2.5 2 0 0 2 2 2 2 Transcriptional regulator of RNA polII, SAGA, subunit zf-DHHC PF01529.15 CDI75091.1 - 0.024 14.0 0.1 0.024 14.0 0.0 2.2 2 0 0 2 2 1 0 DHHC palmitoyltransferase Spore_coat_CotO PF14153.1 CDI75091.1 - 0.3 10.4 41.1 0.51 9.7 11.9 2.2 2 0 0 2 2 2 0 Spore coat protein CotO SR-25 PF10500.4 CDI75091.1 - 0.64 9.4 34.7 0.55 9.6 11.4 2.4 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein DUF1764 PF08576.5 CDI75091.1 - 0.86 10.4 38.4 2.8 8.7 11.2 2.7 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF1764) DUF2052 PF09747.4 CDI75091.1 - 1.7 8.5 36.9 3.6 7.4 11.8 2.2 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) Ycf1 PF05758.7 CDI75091.1 - 2 6.0 26.1 0.27 8.8 5.6 2.0 2 0 0 2 2 2 0 Ycf1 Dynamin_N PF00350.18 CDI75091.1 - 2 8.2 16.2 2.7 7.7 2.6 2.4 2 0 0 2 2 2 0 Dynamin family POP1 PF06978.6 CDI75091.1 - 2.2 7.8 24.2 0.37 10.4 5.0 2.2 2 0 0 2 2 2 0 Ribonucleases P/MRP protein subunit POP1 U79_P34 PF03064.11 CDI75091.1 - 3.1 7.2 26.6 0.067 12.7 3.8 2.2 2 0 0 2 2 2 0 HSV U79 / HCMV P34 SET PF00856.23 CDI75091.1 - 3.1 8.0 9.0 51 4.1 1.3 2.4 2 1 0 2 2 2 0 SET domain eIF3_subunit PF08597.5 CDI75091.1 - 3.5 7.1 35.2 5.5 6.4 11.7 2.6 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit Raftlin PF15250.1 CDI75091.1 - 4.4 5.7 29.6 0.039 12.4 3.3 2.2 2 0 0 2 2 2 0 Raftlin FimP PF09766.4 CDI75091.1 - 6 5.8 60.0 0.024 13.7 12.7 2.1 2 0 0 2 2 2 0 Fms-interacting protein Apt1 PF10351.4 CDI75091.1 - 9.3 4.9 20.8 0.095 11.5 0.1 2.1 2 0 0 2 2 2 0 Golgi-body localisation protein domain Trypsin_2 PF13365.1 CDI75093.1 - 4.8e-11 42.6 0.1 4.8e-11 42.6 0.1 2.4 3 0 0 3 3 3 1 Trypsin-like peptidase domain Trypsin PF00089.21 CDI75093.1 - 3.5e-06 26.7 2.8 9.7e-06 25.3 0.0 2.4 2 0 0 2 2 2 1 Trypsin Apc15p PF05841.6 CDI75094.1 - 0.019 15.6 8.4 0.019 15.6 5.8 5.1 5 1 0 5 5 5 0 Apc15p protein Spt20 PF12090.3 CDI75094.1 - 1.6 8.0 39.3 0.099 11.9 3.3 3.6 4 0 0 4 4 4 0 Spt20 family SKIP_SNW PF02731.10 CDI75094.1 - 2.2 7.7 42.6 0.13 11.6 5.3 3.3 3 0 0 3 3 3 0 SKIP/SNW domain Chorion_2 PF03964.10 CDI75096.1 - 0.005 17.3 5.5 0.005 17.3 3.8 2.3 2 0 0 2 2 2 1 Chorion family 2 CD20 PF04103.10 CDI75096.1 - 0.01 15.7 1.0 0.018 14.9 0.3 1.6 2 0 0 2 2 2 0 CD20-like family zf-B_box PF00643.19 CDI75096.1 - 0.01 15.7 0.7 0.017 14.9 0.5 1.3 1 0 0 1 1 1 0 B-box zinc finger VIT1 PF01988.14 CDI75096.1 - 0.013 14.9 0.8 0.013 14.9 0.5 2.0 2 0 0 2 2 2 0 VIT family Bac_luciferase PF00296.15 CDI75096.1 - 0.017 14.2 3.4 0.027 13.5 2.4 1.3 1 1 0 1 1 1 0 Luciferase-like monooxygenase Peptidase_S8 PF00082.17 CDI75096.1 - 0.053 12.6 0.3 0.053 12.6 0.2 1.6 2 0 0 2 2 2 0 Subtilase family FAM176 PF14851.1 CDI75096.1 - 0.059 13.0 0.4 0.059 13.0 0.3 1.5 2 0 0 2 2 2 0 FAM176 family DUF4094 PF13334.1 CDI75096.1 - 0.073 13.4 4.9 0.071 13.5 1.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4094) SDF PF00375.13 CDI75096.1 - 0.081 11.6 0.0 0.14 10.9 0.0 1.3 1 0 0 1 1 1 0 Sodium:dicarboxylate symporter family Hamartin PF04388.7 CDI75096.1 - 0.14 10.7 6.2 0.16 10.6 4.3 1.0 1 0 0 1 1 1 0 Hamartin protein Pex16 PF08610.5 CDI75096.1 - 0.23 10.4 5.2 0.037 13.0 1.4 1.3 2 0 0 2 2 2 0 Peroxisomal membrane protein (Pex16) FPN1 PF06963.7 CDI75096.1 - 0.23 9.7 1.0 0.38 9.0 0.7 1.3 1 0 0 1 1 1 0 Ferroportin1 (FPN1) OATP PF03137.15 CDI75096.1 - 0.31 9.0 1.4 0.43 8.5 1.0 1.3 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Folate_carrier PF01770.13 CDI75096.1 - 0.32 9.4 2.8 0.091 11.2 0.2 1.3 2 0 0 2 2 2 0 Reduced folate carrier OSTbeta PF15048.1 CDI75096.1 - 0.33 11.0 7.2 0.04 13.9 1.5 1.9 2 0 0 2 2 2 0 Organic solute transporter subunit beta protein TFIIA PF03153.8 CDI75096.1 - 0.53 10.1 24.9 0.8 9.5 17.2 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Neur_chan_memb PF02932.11 CDI75096.1 - 0.68 9.7 3.2 0.92 9.3 2.2 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region FimP PF09766.4 CDI75096.1 - 0.73 8.8 16.3 0.028 13.5 7.3 1.6 2 0 0 2 2 2 0 Fms-interacting protein TetR_C PF02909.12 CDI75096.1 - 1.4 8.5 7.4 0.076 12.6 0.9 1.9 2 0 0 2 2 2 0 Tetracyclin repressor, C-terminal all-alpha domain Ctr PF04145.10 CDI75096.1 - 1.6 8.8 5.9 0.34 10.9 0.8 1.9 2 0 0 2 2 2 0 Ctr copper transporter family Serinc PF03348.10 CDI75096.1 - 2 7.0 11.0 3 6.4 7.6 1.4 1 1 0 1 1 1 0 Serine incorporator (Serinc) DUF2232 PF09991.4 CDI75096.1 - 2.3 7.1 4.4 3.7 6.4 3.1 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) Gag_spuma PF03276.9 CDI75096.1 - 3 6.0 20.7 0.048 11.9 9.2 1.6 2 0 0 2 2 2 0 Spumavirus gag protein Folliculin PF11704.3 CDI75096.1 - 3.3 7.2 7.3 2.1 7.9 3.1 1.8 2 0 0 2 2 2 0 Vesicle coat protein involved in Golgi to plasma membrane transport AIF_C PF14721.1 CDI75096.1 - 5.1 7.3 9.9 1.1 9.5 1.8 2.1 2 0 0 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Peptidase_S15 PF02129.13 CDI75096.1 - 6 6.2 10.3 2.2 7.6 5.4 1.5 1 1 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) PRP3 PF08572.5 CDI75096.1 - 6.7 6.0 16.4 2.5 7.4 6.9 2.2 2 0 0 2 2 2 0 pre-mRNA processing factor 3 (PRP3) IncA PF04156.9 CDI75097.1 - 0.029 13.9 30.9 0.34 10.4 8.7 2.3 2 0 0 2 2 2 0 IncA protein AAA_22 PF13401.1 CDI75097.1 - 8.7 6.5 8.1 2.6 8.2 0.4 2.8 1 1 1 2 2 2 0 AAA domain OmpH PF03938.9 CDI75098.1 - 0.00072 19.5 22.0 0.00072 19.5 15.2 2.8 2 1 0 2 2 2 1 Outer membrane protein (OmpH-like) IncA PF04156.9 CDI75098.1 - 0.018 14.6 28.4 0.2 11.2 8.7 3.4 3 0 0 3 3 3 0 IncA protein TFIIA PF03153.8 CDI75098.1 - 0.2 11.5 35.6 0.023 14.6 3.3 3.1 3 0 0 3 3 3 0 Transcription factor IIA, alpha/beta subunit DDHD PF02862.12 CDI75098.1 - 0.62 9.8 27.7 2.7 7.7 3.7 3.3 3 0 0 3 3 3 0 DDHD domain Trypan_PARP PF05887.6 CDI75098.1 - 1.1 9.1 12.1 1.2 8.9 4.1 2.6 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) DUF2520 PF10728.4 CDI75100.1 - 0.014 14.7 0.6 0.037 13.4 0.4 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF2520) CAF-1_p150 PF11600.3 CDI75101.1 - 7.5e-05 22.2 19.7 9.3e-05 21.9 13.7 1.1 1 0 0 1 1 1 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal DS PF01916.12 CDI75101.1 - 0.00092 18.4 0.1 0.0012 18.0 0.1 1.1 1 0 0 1 1 1 1 Deoxyhypusine synthase SprA-related PF12118.3 CDI75101.1 - 0.0099 15.2 22.0 0.013 14.8 15.3 1.2 1 0 0 1 1 1 1 SprA-related family DUF533 PF04391.7 CDI75101.1 - 0.022 14.1 7.9 0.025 13.9 5.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF533) TMEM51 PF15345.1 CDI75101.1 - 0.023 14.4 11.4 0.028 14.1 7.9 1.1 1 0 0 1 1 1 0 Transmembrane protein 51 DUF3357 PF11837.3 CDI75101.1 - 0.028 14.2 5.1 0.056 13.2 3.4 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF3357) TMEM154 PF15102.1 CDI75101.1 - 0.029 14.0 4.1 0.04 13.6 2.8 1.2 1 0 0 1 1 1 0 TMEM154 protein family Med15 PF09606.5 CDI75101.1 - 0.031 12.4 18.9 0.028 12.6 13.1 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF4175 PF13779.1 CDI75101.1 - 0.033 11.9 17.1 0.03 12.0 11.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) SCF PF02404.10 CDI75101.1 - 0.069 12.3 7.0 0.09 11.9 4.8 1.1 1 0 0 1 1 1 0 Stem cell factor PspB PF06667.7 CDI75101.1 - 0.073 13.0 0.3 0.11 12.3 0.2 1.4 1 0 0 1 1 1 0 Phage shock protein B DUF4179 PF13786.1 CDI75101.1 - 0.082 13.1 0.1 0.13 12.4 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4179) Conotoxin PF02950.12 CDI75101.1 - 0.11 13.2 6.4 0.17 12.7 2.1 2.1 2 0 0 2 2 2 0 Conotoxin FHIPEP PF00771.15 CDI75101.1 - 0.14 10.4 3.9 0.14 10.5 2.7 1.1 1 0 0 1 1 1 0 FHIPEP family SID-1_RNA_chan PF13965.1 CDI75101.1 - 0.17 9.9 3.4 0.18 9.9 2.4 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Corona_nucleoca PF00937.13 CDI75101.1 - 0.19 10.6 22.2 0.22 10.4 15.4 1.0 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein Trp_oprn_chp PF09534.5 CDI75101.1 - 0.22 11.1 1.1 0.25 10.9 0.8 1.1 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Serinc PF03348.10 CDI75101.1 - 0.26 9.9 9.0 0.29 9.8 6.2 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) GDE_N PF12439.3 CDI75101.1 - 0.32 10.2 3.3 0.37 10.0 2.3 1.2 1 0 0 1 1 1 0 Glycogen debranching enzyme N terminal Suf PF05843.9 CDI75101.1 - 0.35 10.5 16.6 0.43 10.2 11.5 1.0 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) UPF0052 PF01933.13 CDI75101.1 - 0.4 9.9 2.5 0.43 9.8 1.8 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0052 DDHD PF02862.12 CDI75101.1 - 0.42 10.3 13.7 0.6 9.8 9.5 1.2 1 0 0 1 1 1 0 DDHD domain AUX_IAA PF02309.11 CDI75101.1 - 0.45 10.2 11.1 0.53 9.9 7.7 1.1 1 0 0 1 1 1 0 AUX/IAA family SAGA-Tad1 PF12767.2 CDI75101.1 - 0.57 9.8 15.1 0.63 9.6 10.4 1.0 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit BLVR PF06375.6 CDI75101.1 - 0.58 9.9 14.9 0.93 9.2 10.3 1.4 1 1 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) DUF3043 PF11241.3 CDI75101.1 - 1.2 8.7 6.2 1.3 8.6 4.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) Peptidase_U57 PF05582.7 CDI75101.1 - 1.4 7.8 6.7 1.5 7.7 4.7 1.1 1 0 0 1 1 1 0 YabG peptidase U57 polyprenyl_synt PF00348.12 CDI75101.1 - 1.7 7.4 7.7 2.1 7.1 5.4 1.1 1 0 0 1 1 1 0 Polyprenyl synthetase Blt1 PF12754.2 CDI75101.1 - 1.7 8.1 15.8 2.1 7.8 10.9 1.0 1 0 0 1 1 1 0 Cell-cycle control medial ring component Zip PF02535.17 CDI75101.1 - 1.8 7.5 7.0 1.9 7.4 4.9 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter FLO_LFY PF01698.11 CDI75101.1 - 1.8 7.3 11.5 2 7.1 8.0 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein DivIC PF04977.10 CDI75101.1 - 3.2 7.2 15.6 4.6 6.8 10.8 1.2 1 0 0 1 1 1 0 Septum formation initiator eIF-3_zeta PF05091.7 CDI75101.1 - 3.4 6.1 14.5 3.6 6.1 10.0 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) RR_TM4-6 PF06459.7 CDI75101.1 - 4.5 7.0 13.0 5.2 6.8 9.0 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF3499 PF12005.3 CDI75101.1 - 6.1 7.0 8.0 19 5.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3499) DUF4199 PF13858.1 CDI75101.1 - 6.4 6.6 6.7 8.7 6.2 4.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) Secretin_N_2 PF07655.8 CDI75101.1 - 7.1 7.0 18.8 1 9.7 6.2 2.1 2 0 0 2 2 2 0 Secretin N-terminal domain Hid1 PF12722.2 CDI75101.1 - 7.3 4.1 13.8 10 3.6 9.6 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SOBP PF15279.1 CDI75101.1 - 7.7 6.8 16.4 9.6 6.4 11.3 1.0 1 0 0 1 1 1 0 Sine oculis-binding protein DUF4228 PF14009.1 CDI75101.1 - 9.7 6.2 13.6 11 6.0 9.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4228) SprA-related PF12118.3 CDI75102.1 - 0.0015 17.9 53.2 0.0017 17.7 36.9 1.1 1 0 0 1 1 1 1 SprA-related family SID-1_RNA_chan PF13965.1 CDI75102.1 - 0.2 9.7 14.6 0.23 9.5 10.1 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 PBP1_TM PF14812.1 CDI75102.1 - 0.37 11.1 12.4 2.7 8.3 0.0 2.1 1 1 1 2 2 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Corona_nucleoca PF00937.13 CDI75102.1 - 0.62 8.9 37.7 0.55 9.1 25.5 1.4 1 1 0 1 1 1 0 Coronavirus nucleocapsid protein AAA_23 PF13476.1 CDI75102.1 - 0.65 10.2 27.0 0.73 10.1 18.7 1.0 1 0 0 1 1 1 0 AAA domain TMEM51 PF15345.1 CDI75102.1 - 0.73 9.4 31.1 0.093 12.4 18.1 1.8 1 1 0 2 2 2 0 Transmembrane protein 51 Med15 PF09606.5 CDI75102.1 - 0.9 7.6 64.6 1 7.4 44.8 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal 7TM_GPCR_Srw PF10324.4 CDI75102.1 - 0.91 8.5 4.5 1.2 8.2 3.1 1.3 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srw GRP PF07172.6 CDI75102.1 - 0.98 9.9 13.4 0.15 12.5 5.3 2.4 1 1 1 2 2 2 0 Glycine rich protein family TAS2R PF05296.8 CDI75102.1 - 1.1 8.1 5.1 1.3 7.8 3.6 1.2 1 0 0 1 1 1 0 Mammalian taste receptor protein (TAS2R) SAGA-Tad1 PF12767.2 CDI75102.1 - 2.1 7.9 31.0 2.5 7.7 21.5 1.1 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit Apt1 PF10351.4 CDI75102.1 - 2.4 6.9 25.1 3 6.6 17.4 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain Plant_vir_prot PF01307.12 CDI75102.1 - 2.8 7.6 4.9 2.1 8.0 1.9 2.0 1 1 0 1 1 1 0 Plant viral movement protein DUF2782 PF11191.3 CDI75102.1 - 3.2 7.7 18.9 4.9 7.1 2.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2782) Cas1_AcylT PF07779.7 CDI75102.1 - 4.8 5.5 7.1 5.8 5.2 4.9 1.1 1 0 0 1 1 1 0 10 TM Acyl Transferase domain found in Cas1p TRAP_alpha PF03896.11 CDI75102.1 - 6.2 5.7 12.2 0.35 9.8 3.7 1.9 1 1 1 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit DUF4446 PF14584.1 CDI75102.1 - 7.2 6.4 12.2 14 5.4 8.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) ALG3 PF05208.8 CDI75102.1 - 8.5 5.4 10.0 10 5.2 6.9 1.1 1 0 0 1 1 1 0 ALG3 protein SR-25 PF10500.4 CDI75103.1 - 1.4e-06 27.9 19.6 1.4e-06 27.9 13.6 4.7 5 1 1 6 6 4 1 Nuclear RNA-splicing-associated protein AAA_25 PF13481.1 CDI75103.1 - 0.00036 20.0 0.4 0.00085 18.7 0.3 1.6 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 CDI75103.1 - 0.00062 19.9 0.5 0.00062 19.9 0.4 3.1 4 1 0 4 4 3 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 CDI75103.1 - 0.0008 19.1 0.3 0.0033 17.1 0.1 2.1 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 CDI75103.1 - 0.0022 17.9 0.0 0.0022 17.9 0.0 3.5 3 1 1 4 4 3 1 AAA ATPase domain AAA_22 PF13401.1 CDI75103.1 - 0.0095 16.0 0.1 0.0095 16.0 0.1 2.5 3 0 0 3 3 3 1 AAA domain AAA_24 PF13479.1 CDI75103.1 - 0.01 15.4 0.3 0.01 15.4 0.2 3.0 3 0 0 3 3 3 0 AAA domain AAA_19 PF13245.1 CDI75103.1 - 0.014 15.1 3.9 0.014 15.1 2.7 3.1 3 0 0 3 3 3 0 Part of AAA domain OmpH PF03938.9 CDI75103.1 - 0.029 14.2 43.3 0.09 12.7 7.2 3.5 3 0 0 3 3 3 0 Outer membrane protein (OmpH-like) AAA_17 PF13207.1 CDI75103.1 - 0.081 13.7 0.1 0.15 12.8 0.1 1.4 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 CDI75103.1 - 0.38 9.8 5.9 0.29 10.2 0.1 2.8 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI Pox_E2-like PF04497.7 CDI75103.1 - 6 4.7 13.3 2.9 5.7 2.9 2.1 2 0 0 2 2 2 0 Poxviridae protein Pkinase PF00069.20 CDI75105.1 - 5.7e-11 42.0 0.0 5.7e-11 42.0 0.0 3.8 4 1 1 5 5 5 1 Protein kinase domain EF-hand_1 PF00036.27 CDI75105.1 - 2.3e-08 32.7 0.0 0.068 12.5 0.0 3.4 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.1 CDI75105.1 - 7.8e-07 28.4 0.2 0.016 15.0 0.0 3.4 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.1 CDI75105.1 - 1.6e-06 28.1 0.0 0.0025 17.9 0.0 2.4 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 CDI75105.1 - 3.3e-06 26.6 0.2 0.028 14.0 0.1 3.3 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_5 PF13202.1 CDI75105.1 - 3.3e-06 26.1 0.5 1.8 8.0 0.0 3.5 3 0 0 3 3 3 3 EF hand Suf PF05843.9 CDI75105.1 - 0.00017 21.4 48.5 0.0063 16.2 1.0 4.3 4 0 0 4 4 4 3 Suppressor of forked protein (Suf) DUF3449 PF11931.3 CDI75105.1 - 0.034 13.6 38.7 0.075 12.5 7.8 4.4 4 0 0 4 4 4 0 Domain of unknown function (DUF3449) PRCC PF10253.4 CDI75105.1 - 0.04 14.5 0.5 0.04 14.5 0.3 6.2 6 0 0 6 6 5 0 Mitotic checkpoint regulator, MAD2B-interacting TOBE_2 PF08402.5 CDI75105.1 - 0.16 12.0 2.9 1.4 8.9 2.0 2.7 1 0 0 1 1 1 0 TOBE domain SpoIIIAH PF12685.2 CDI75105.1 - 0.28 10.6 44.7 0.11 11.9 2.8 5.2 4 1 1 5 5 5 0 SpoIIIAH-like protein Dehydrin PF00257.14 CDI75105.1 - 0.3 11.3 42.5 2.6 8.3 0.2 4.9 4 0 0 4 4 4 0 Dehydrin CD20 PF04103.10 CDI75105.1 - 4.5 7.1 22.6 5.2 6.9 0.0 5.3 6 0 0 6 6 5 0 CD20-like family TP_methylase PF00590.15 CDI75106.1 - 1.9e-09 37.5 0.1 2.2e-09 37.3 0.0 1.0 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases UQ_con PF00179.21 CDI75107.1 - 4.2e-47 159.1 0.0 4.8e-47 158.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 CDI75107.1 - 4.4e-05 23.2 0.0 4.9e-05 23.0 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 CDI75107.1 - 0.0007 19.4 0.0 0.00085 19.1 0.0 1.2 1 0 0 1 1 1 1 RWD domain APG5 PF04106.7 CDI75108.1 - 2.3e-25 89.2 0.0 7.5e-25 87.5 0.0 1.9 1 1 0 1 1 1 1 Autophagy protein Apg5 BRF1 PF07741.8 CDI75109.1 - 0.13 12.4 15.6 0.14 12.3 10.8 1.1 1 0 0 1 1 1 0 Brf1-like TBP-binding domain FimP PF09766.4 CDI75109.1 - 0.8 8.7 28.6 0.9 8.5 19.8 1.1 1 0 0 1 1 1 0 Fms-interacting protein DNA_pol3_a_NII PF11490.3 CDI75109.1 - 0.85 9.2 25.8 1.1 8.8 17.9 1.2 1 0 0 1 1 1 0 DNA polymerase III polC-type N-terminus II DDRGK PF09756.4 CDI75109.1 - 0.97 8.8 22.8 1 8.7 15.8 1.1 1 0 0 1 1 1 0 DDRGK domain GAGA_bind PF06217.7 CDI75109.1 - 1.9 8.3 15.5 1.9 8.3 10.7 1.0 1 0 0 1 1 1 0 GAGA binding protein-like family YABBY PF04690.8 CDI75109.1 - 2 8.6 10.6 2.1 8.5 7.3 1.1 1 0 0 1 1 1 0 YABBY protein NinG PF05766.7 CDI75109.1 - 2.1 8.0 20.1 2.3 7.9 13.9 1.0 1 0 0 1 1 1 0 Bacteriophage Lambda NinG protein FYDLN_acid PF09538.5 CDI75109.1 - 2.4 8.7 10.5 2.5 8.7 7.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) Peptidase_S49_N PF08496.5 CDI75109.1 - 3 7.6 13.9 3.1 7.5 9.7 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal RNA_pol_Rpc4 PF05132.9 CDI75109.1 - 3.4 7.6 15.1 4.3 7.3 10.4 1.1 1 0 0 1 1 1 0 RNA polymerase III RPC4 DUF1764 PF08576.5 CDI75109.1 - 3.5 8.4 19.3 3.8 8.3 13.4 1.2 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) PH_4 PF15404.1 CDI75109.1 - 3.6 7.0 12.8 4.1 6.8 8.9 1.2 1 0 0 1 1 1 0 Pleckstrin homology domain DUF3043 PF11241.3 CDI75109.1 - 3.8 7.0 11.8 4.7 6.7 8.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) AIF_C PF14721.1 CDI75109.1 - 3.9 7.7 14.0 3.9 7.7 9.7 1.1 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Dala_Dala_lig_N PF01820.16 CDI75109.1 - 4.1 7.7 9.1 4.8 7.5 6.3 1.2 1 0 0 1 1 1 0 D-ala D-ala ligase N-terminus FLO_LFY PF01698.11 CDI75109.1 - 5 5.8 17.8 4.7 5.9 12.4 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein DUF3464 PF11947.3 CDI75109.1 - 5.3 6.4 13.9 5.6 6.4 9.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) Bud13 PF09736.4 CDI75109.1 - 5.4 7.2 23.6 5.6 7.2 16.4 1.1 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex Dynamin_N PF00350.18 CDI75109.1 - 5.5 6.7 13.4 5.6 6.7 9.3 1.0 1 0 0 1 1 1 0 Dynamin family FAM176 PF14851.1 CDI75109.1 - 5.6 6.6 13.0 6.9 6.3 9.0 1.1 1 0 0 1 1 1 0 FAM176 family SeqA PF03925.8 CDI75109.1 - 6.1 6.4 15.7 6.4 6.4 10.8 1.1 1 0 0 1 1 1 0 SeqA protein DUF1266 PF06889.6 CDI75109.1 - 6.2 6.5 12.5 7.1 6.4 8.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1266) DUF3306 PF11748.3 CDI75109.1 - 6.2 7.5 17.1 6.6 7.4 11.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3306) PRTP PF01366.13 CDI75109.1 - 6.9 4.5 15.0 6.8 4.5 10.4 1.0 1 0 0 1 1 1 0 Herpesvirus processing and transport protein Gti1_Pac2 PF09729.4 CDI75109.1 - 7.2 6.4 12.9 7.4 6.4 8.9 1.1 1 0 0 1 1 1 0 Gti1/Pac2 family EIIBC-GUT_N PF03612.9 CDI75109.1 - 7.4 6.1 14.0 8.4 5.9 9.7 1.1 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus FAM60A PF15396.1 CDI75109.1 - 7.5 6.2 13.1 7.7 6.1 9.0 1.1 1 0 0 1 1 1 0 Protein Family FAM60A Baculo_PP31 PF05311.6 CDI75109.1 - 8.8 5.5 18.4 8.3 5.5 12.8 1.0 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) DUF4175 PF13779.1 CDI75109.1 - 8.9 3.8 45.1 8.3 3.9 31.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Band_3_cyto PF07565.8 CDI75109.1 - 9 5.7 19.2 8.4 5.8 13.3 1.0 1 0 0 1 1 1 0 Band 3 cytoplasmic domain TraH_2 PF06871.6 CDI75109.1 - 9 5.6 8.9 9.5 5.6 6.2 1.1 1 0 0 1 1 1 0 TraH_2 RIC3 PF15361.1 CDI75109.1 - 9.3 6.4 16.5 9.9 6.3 11.4 1.1 1 0 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 NARP1 PF12569.3 CDI75109.1 - 9.3 4.8 18.1 8.4 5.0 12.6 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Endonuc_Holl PF10107.4 CDI75109.1 - 9.9 5.8 17.8 11 5.6 12.3 1.1 1 0 0 1 1 1 0 Endonuclease related to archaeal Holliday junction resolvase Pex14_N PF04695.8 CDI75110.1 - 0.0036 17.3 15.8 0.0041 17.1 11.0 1.2 1 0 0 1 1 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region PAT1 PF09770.4 CDI75110.1 - 0.007 14.6 27.8 0.0066 14.7 19.3 1.0 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 Med15 PF09606.5 CDI75110.1 - 0.019 13.2 39.4 0.017 13.3 27.3 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal FimP PF09766.4 CDI75110.1 - 0.033 13.2 22.7 0.037 13.0 15.7 1.1 1 0 0 1 1 1 0 Fms-interacting protein Baculo_PP31 PF05311.6 CDI75110.1 - 0.079 12.2 13.3 0.078 12.2 9.2 1.1 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) TFIIA PF03153.8 CDI75110.1 - 0.12 12.3 24.1 0.12 12.2 16.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Gag_spuma PF03276.9 CDI75110.1 - 0.16 10.2 23.0 0.15 10.3 15.9 1.1 1 0 0 1 1 1 0 Spumavirus gag protein EIIBC-GUT_N PF03612.9 CDI75110.1 - 0.17 11.4 9.8 0.19 11.2 6.8 1.1 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus MMR1 PF08505.5 CDI75110.1 - 0.18 11.8 19.8 0.2 11.6 13.7 1.1 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein Spore_coat_CotO PF14153.1 CDI75110.1 - 0.18 11.2 19.4 0.2 11.1 13.5 1.2 1 0 0 1 1 1 0 Spore coat protein CotO SprA-related PF12118.3 CDI75110.1 - 0.21 10.8 32.5 0.24 10.7 22.5 1.1 1 0 0 1 1 1 0 SprA-related family DUF3408 PF11888.3 CDI75110.1 - 0.21 11.5 12.8 0.3 11.0 8.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) Suf PF05843.9 CDI75110.1 - 0.27 10.9 17.8 0.3 10.7 12.4 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Dala_Dala_lig_N PF01820.16 CDI75110.1 - 0.29 11.4 5.7 0.35 11.1 3.9 1.2 1 0 0 1 1 1 0 D-ala D-ala ligase N-terminus DUF4557 PF15101.1 CDI75110.1 - 0.37 10.6 23.2 0.39 10.5 16.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) AIF_C PF14721.1 CDI75110.1 - 0.44 10.7 10.7 0.56 10.4 7.4 1.3 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term DUF4175 PF13779.1 CDI75110.1 - 0.44 8.1 42.1 0.41 8.2 29.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Band_3_cyto PF07565.8 CDI75110.1 - 0.49 9.8 15.1 0.57 9.6 10.5 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain PAXIP1_C PF15364.1 CDI75110.1 - 0.5 10.2 15.3 0.58 10.0 10.6 1.1 1 0 0 1 1 1 0 PAXIP1-associated-protein-1 C term PTIP binding protein Serinc PF03348.10 CDI75110.1 - 0.55 8.8 10.8 0.54 8.9 7.5 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) RED_N PF07808.8 CDI75110.1 - 0.55 9.4 19.6 0.67 9.1 13.6 1.2 1 0 0 1 1 1 0 RED-like protein N-terminal region Bud13 PF09736.4 CDI75110.1 - 0.55 10.4 18.2 0.6 10.3 12.6 1.3 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex DUF1266 PF06889.6 CDI75110.1 - 0.56 9.9 9.5 0.68 9.7 6.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1266) DUF913 PF06025.7 CDI75110.1 - 0.62 8.7 6.1 0.6 8.7 4.2 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Peroxin-13_N PF04088.8 CDI75110.1 - 0.62 10.0 8.6 0.87 9.5 6.0 1.2 1 0 0 1 1 1 0 Peroxin 13, N-terminal region Tim54 PF11711.3 CDI75110.1 - 0.67 8.4 9.4 0.73 8.3 6.5 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DDHD PF02862.12 CDI75110.1 - 0.7 9.6 13.8 0.79 9.4 9.6 1.1 1 0 0 1 1 1 0 DDHD domain R_equi_Vir PF05526.6 CDI75110.1 - 0.72 9.4 5.3 0.87 9.2 3.6 1.1 1 0 0 1 1 1 0 Rhodococcus equi virulence-associated protein AUX_IAA PF02309.11 CDI75110.1 - 0.74 9.5 12.5 0.76 9.4 8.7 1.1 1 0 0 1 1 1 0 AUX/IAA family PXA PF02194.10 CDI75110.1 - 0.75 9.3 10.3 0.87 9.1 7.1 1.1 1 0 0 1 1 1 0 PXA domain Gti1_Pac2 PF09729.4 CDI75110.1 - 0.76 9.6 8.9 0.86 9.4 6.2 1.2 1 0 0 1 1 1 0 Gti1/Pac2 family Folate_carrier PF01770.13 CDI75110.1 - 0.78 8.1 8.6 0.83 8.0 6.0 1.1 1 0 0 1 1 1 0 Reduced folate carrier FAM176 PF14851.1 CDI75110.1 - 0.82 9.3 7.4 0.92 9.1 5.1 1.3 1 0 0 1 1 1 0 FAM176 family DDRGK PF09756.4 CDI75110.1 - 0.86 8.9 20.4 0.93 8.8 14.1 1.3 1 0 0 1 1 1 0 DDRGK domain Ctr PF04145.10 CDI75110.1 - 0.89 9.6 9.7 1.1 9.3 6.7 1.2 1 0 0 1 1 1 0 Ctr copper transporter family Host_attach PF10116.4 CDI75110.1 - 1.1 9.5 13.7 1.3 9.2 9.5 1.2 1 0 0 1 1 1 0 Protein required for attachment to host cells CPSF100_C PF13299.1 CDI75110.1 - 1.1 9.4 11.6 1.1 9.3 8.0 1.1 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal XAP5 PF04921.9 CDI75110.1 - 1.1 8.7 11.9 1.2 8.6 8.2 1.2 1 0 0 1 1 1 0 XAP5, circadian clock regulator HGTP_anticodon2 PF12745.2 CDI75110.1 - 1.2 8.2 13.3 1.4 8.0 9.2 1.1 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs Bac_luciferase PF00296.15 CDI75110.1 - 1.3 8.0 5.3 1.6 7.7 3.7 1.1 1 0 0 1 1 1 0 Luciferase-like monooxygenase SLD3 PF08639.5 CDI75110.1 - 1.3 7.5 19.0 1.6 7.2 13.2 1.1 1 0 0 1 1 1 0 DNA replication regulator SLD3 SpoVR PF04293.8 CDI75110.1 - 1.4 7.2 14.9 1.5 7.0 10.3 1.0 1 0 0 1 1 1 0 SpoVR like protein ST7 PF04184.7 CDI75110.1 - 1.4 7.1 7.0 1.6 6.8 4.8 1.0 1 0 0 1 1 1 0 ST7 protein BORG_CEP PF14957.1 CDI75110.1 - 1.4 9.8 8.4 1.6 9.6 5.8 1.4 1 0 0 1 1 1 0 Cdc42 effector Kei1 PF08552.6 CDI75110.1 - 1.4 8.5 8.2 1.5 8.3 5.7 1.2 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 eIF-3_zeta PF05091.7 CDI75110.1 - 1.4 7.4 20.2 1.5 7.3 14.0 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Zip PF02535.17 CDI75110.1 - 1.5 7.7 4.0 1.7 7.6 2.8 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter RR_TM4-6 PF06459.7 CDI75110.1 - 1.5 8.6 16.4 1.6 8.5 11.4 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Peptidase_S15 PF02129.13 CDI75110.1 - 1.5 8.1 10.8 1.7 8.0 7.5 1.2 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Ndc1_Nup PF09531.5 CDI75110.1 - 1.5 7.1 12.1 1.4 7.2 8.4 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Glyco_transf_15 PF01793.11 CDI75110.1 - 1.6 7.6 13.4 1.8 7.4 9.3 1.1 1 0 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase Peptidase_U57 PF05582.7 CDI75110.1 - 1.8 7.4 11.6 2 7.3 8.0 1.1 1 0 0 1 1 1 0 YabG peptidase U57 TMEM51 PF15345.1 CDI75110.1 - 1.9 8.1 13.2 2 8.0 9.1 1.3 1 0 0 1 1 1 0 Transmembrane protein 51 Pex16 PF08610.5 CDI75110.1 - 1.9 7.3 14.8 2.2 7.2 10.2 1.1 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) AbiH PF14253.1 CDI75110.1 - 2 7.9 8.4 2.4 7.6 5.8 1.1 1 0 0 1 1 1 0 Bacteriophage abortive infection AbiH Mem_trans PF03547.13 CDI75110.1 - 2.2 6.5 6.4 2.3 6.4 4.4 1.1 1 0 0 1 1 1 0 Membrane transport protein Hid1 PF12722.2 CDI75110.1 - 2.2 5.8 15.8 2.2 5.8 10.9 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein FLO_LFY PF01698.11 CDI75110.1 - 2.3 7.0 15.9 2.4 6.9 11.0 1.2 1 0 0 1 1 1 0 Floricaula / Leafy protein Otopetrin PF03189.8 CDI75110.1 - 2.4 7.0 7.4 2.9 6.8 5.2 1.0 1 0 0 1 1 1 0 Otopetrin Pal1 PF08316.6 CDI75110.1 - 2.5 8.5 6.1 2.8 8.3 4.3 1.3 1 0 0 1 1 1 0 Pal1 cell morphology protein SID-1_RNA_chan PF13965.1 CDI75110.1 - 2.6 6.0 11.1 3 5.9 7.7 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DHHW PF14286.1 CDI75110.1 - 2.7 7.2 9.9 2.8 7.1 6.9 1.1 1 0 0 1 1 1 0 DHHW protein Paf1 PF03985.8 CDI75110.1 - 2.8 6.5 19.8 3.2 6.3 13.7 1.1 1 0 0 1 1 1 0 Paf1 DUF2149 PF09919.4 CDI75110.1 - 3 7.9 9.3 4.1 7.5 6.4 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2149) Pox_P4B PF03292.9 CDI75110.1 - 3 5.6 7.8 3.2 5.5 5.4 1.0 1 0 0 1 1 1 0 Poxvirus P4B major core protein OATP PF03137.15 CDI75110.1 - 3.1 5.7 11.3 3.6 5.5 7.8 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family DUF853 PF05872.7 CDI75110.1 - 3.2 6.0 12.8 3.2 6.0 8.9 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) HD-ZIP_N PF04618.7 CDI75110.1 - 3.2 8.3 7.3 4.5 7.8 5.1 1.3 1 0 0 1 1 1 0 HD-ZIP protein N terminus GOLD_2 PF13897.1 CDI75110.1 - 3.3 7.9 5.1 4 7.6 3.5 1.3 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking DUF775 PF05603.7 CDI75110.1 - 3.7 7.0 14.6 4.6 6.7 10.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF775) F-protein PF00469.15 CDI75110.1 - 3.8 6.8 12.2 4.1 6.7 8.4 1.1 1 0 0 1 1 1 0 Negative factor, (F-Protein) or Nef FHIPEP PF00771.15 CDI75110.1 - 4.1 5.6 9.9 4.2 5.5 6.9 1.1 1 0 0 1 1 1 0 FHIPEP family Herpes_DNAp_acc PF04929.7 CDI75110.1 - 4.1 6.2 15.7 4.8 6.0 10.9 1.0 1 0 0 1 1 1 0 Herpes DNA replication accessory factor CRF1 PF10380.4 CDI75110.1 - 4.2 7.7 8.6 5.5 7.3 6.0 1.3 1 0 0 1 1 1 0 Transcription factor CRF1 DUF4407 PF14362.1 CDI75110.1 - 4.2 6.2 19.2 4.7 6.0 13.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) eIF3_subunit PF08597.5 CDI75110.1 - 4.5 6.7 17.2 4.6 6.7 12.0 1.2 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit Shisa PF13908.1 CDI75110.1 - 4.6 7.3 16.2 5.7 7.0 11.3 1.2 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Endonuc_Holl PF10107.4 CDI75110.1 - 4.6 6.9 14.4 5.6 6.6 10.0 1.3 1 0 0 1 1 1 0 Endonuclease related to archaeal Holliday junction resolvase CDC45 PF02724.9 CDI75110.1 - 4.9 5.0 19.4 5.4 4.9 13.5 1.0 1 0 0 1 1 1 0 CDC45-like protein DUF2126 PF09899.4 CDI75110.1 - 5.6 4.8 10.8 6.2 4.7 7.5 1.1 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) Plasmodium_Vir PF05795.6 CDI75110.1 - 5.7 6.0 6.5 5.6 6.0 4.5 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Nucleoside_tran PF01733.13 CDI75110.1 - 6 5.9 6.8 7 5.7 4.7 1.1 1 0 0 1 1 1 0 Nucleoside transporter DUF3260 PF11658.3 CDI75110.1 - 6.1 4.8 12.4 6.8 4.7 8.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3260) DUF605 PF04652.11 CDI75110.1 - 6.1 6.1 20.5 7.2 5.9 14.2 1.1 1 0 0 1 1 1 0 Vta1 like DUF4011 PF13195.1 CDI75110.1 - 6.1 6.8 11.7 6.9 6.6 8.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4011) BAF1_ABF1 PF04684.8 CDI75110.1 - 6.5 5.4 32.8 8 5.1 22.7 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Hom_end_hint PF05203.11 CDI75110.1 - 6.6 6.4 12.2 7.2 6.2 8.5 1.1 1 0 0 1 1 1 0 Hom_end-associated Hint FemAB PF02388.11 CDI75110.1 - 6.6 5.3 16.5 7.1 5.1 11.4 1.1 1 0 0 1 1 1 0 FemAB family Glyco_transf_6 PF03414.8 CDI75110.1 - 6.6 5.0 9.2 7.6 4.8 6.4 1.1 1 0 0 1 1 1 0 Glycosyltransferase family 6 FliP PF00813.15 CDI75110.1 - 6.9 6.3 6.2 8.2 6.0 4.3 1.3 1 0 0 1 1 1 0 FliP family UPF0560 PF10577.4 CDI75110.1 - 8.5 4.4 22.3 9.1 4.3 15.4 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Neur_chan_memb PF02932.11 CDI75110.1 - 9.3 6.0 11.4 10 5.9 7.9 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF2052 PF09747.4 CDI75112.1 - 0.096 12.5 47.5 0.46 10.3 9.9 3.4 3 0 0 3 3 3 0 Coiled-coil domain containing protein (DUF2052) Spore_YhcN_YlaJ PF09580.5 CDI75112.1 - 0.31 11.1 36.2 0.17 12.0 3.7 3.4 3 0 0 3 3 3 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) DUF4647 PF15504.1 CDI75112.1 - 1.9 7.2 48.5 0.41 9.4 7.9 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4647) Ribosomal_S17e PF00833.13 CDI75113.1 - 4.9e-58 194.2 1.8 4.9e-58 194.2 1.3 3.0 3 0 0 3 3 3 1 Ribosomal S17 SprA-related PF12118.3 CDI75113.1 - 0.00014 21.3 10.9 0.00014 21.3 7.6 5.1 3 2 0 4 4 4 1 SprA-related family UPF0564 PF10595.4 CDI75113.1 - 0.025 13.5 0.2 0.025 13.5 0.1 4.2 4 0 0 4 4 4 0 Uncharacterised protein family UPF0564 Spt20 PF12090.3 CDI75113.1 - 0.033 13.5 36.0 0.36 10.1 2.8 4.7 4 0 0 4 4 4 0 Spt20 family SR-25 PF10500.4 CDI75114.1 - 1.2e-05 24.9 15.7 1.6e-05 24.5 10.9 1.3 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein G-alpha PF00503.15 CDI75114.1 - 1.7e-05 23.6 6.4 3.2e-05 22.8 4.4 1.5 1 1 0 1 1 1 1 G-protein alpha subunit AAA_29 PF13555.1 CDI75114.1 - 0.00066 19.1 0.1 0.00066 19.1 0.0 1.9 2 0 0 2 2 1 1 P-loop containing region of AAA domain AAA_17 PF13207.1 CDI75114.1 - 0.0013 19.5 0.3 0.0019 19.0 0.2 1.3 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 CDI75114.1 - 0.0023 17.9 0.3 0.0023 17.9 0.2 2.1 1 1 1 2 2 2 1 AAA ATPase domain NB-ARC PF00931.17 CDI75114.1 - 0.0033 16.3 0.1 0.0045 15.8 0.1 1.2 1 0 0 1 1 1 1 NB-ARC domain ATP_bind_1 PF03029.12 CDI75114.1 - 0.0038 16.7 0.7 0.0061 16.1 0.5 1.3 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_19 PF13245.1 CDI75114.1 - 0.0039 16.8 1.0 0.0039 16.8 0.7 2.3 1 1 1 2 2 2 1 Part of AAA domain AAA_30 PF13604.1 CDI75114.1 - 0.0051 16.4 0.9 0.0051 16.4 0.6 2.2 1 1 1 2 2 1 1 AAA domain AAA_33 PF13671.1 CDI75114.1 - 0.0064 16.3 4.0 0.034 14.0 0.3 2.2 2 0 0 2 2 2 1 AAA domain Pex14_N PF04695.8 CDI75114.1 - 0.0083 16.1 16.9 0.013 15.5 11.7 1.3 1 0 0 1 1 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Viral_helicase1 PF01443.13 CDI75114.1 - 0.013 15.0 4.4 0.046 13.2 0.1 2.1 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase T2SE PF00437.15 CDI75114.1 - 0.013 14.4 0.1 0.013 14.4 0.1 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein DUF4614 PF15391.1 CDI75114.1 - 0.013 15.2 17.1 0.016 15.0 11.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) NTPase_1 PF03266.10 CDI75114.1 - 0.014 15.1 0.2 0.02 14.5 0.1 1.3 1 0 0 1 1 1 0 NTPase NACHT PF05729.7 CDI75114.1 - 0.016 14.8 0.2 0.016 14.8 0.2 1.5 2 0 0 2 2 1 0 NACHT domain Zeta_toxin PF06414.7 CDI75114.1 - 0.018 14.1 0.1 0.018 14.1 0.1 1.7 2 0 0 2 2 2 0 Zeta toxin AAA_23 PF13476.1 CDI75114.1 - 0.019 15.3 0.3 0.21 11.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 CDI75114.1 - 0.022 15.0 0.4 0.035 14.4 0.3 1.3 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 CDI75114.1 - 0.023 14.8 3.6 0.033 14.3 0.3 2.1 1 1 1 2 2 2 0 AAA domain ABC_tran PF00005.22 CDI75114.1 - 0.046 14.0 0.4 0.046 14.0 0.3 2.1 1 1 1 2 2 2 0 ABC transporter cobW PF02492.14 CDI75114.1 - 0.048 13.1 0.4 0.081 12.3 0.2 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain DUF815 PF05673.8 CDI75114.1 - 0.072 12.0 0.0 0.077 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) MobB PF03205.9 CDI75114.1 - 0.1 12.2 0.3 0.25 11.0 0.2 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B FLO_LFY PF01698.11 CDI75114.1 - 0.12 11.2 5.0 0.13 11.0 3.5 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein APS_kinase PF01583.15 CDI75114.1 - 0.12 11.9 0.1 0.22 11.1 0.1 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase Adeno_IVa2 PF02456.10 CDI75114.1 - 0.12 10.9 0.1 0.12 11.0 0.1 1.2 1 0 0 1 1 1 0 Adenovirus IVa2 protein Macoilin PF09726.4 CDI75114.1 - 0.16 10.2 17.8 0.16 10.2 12.4 1.0 1 0 0 1 1 1 0 Transmembrane protein AAA_14 PF13173.1 CDI75114.1 - 0.22 11.4 0.1 0.22 11.4 0.0 1.6 2 0 0 2 2 1 0 AAA domain NARP1 PF12569.3 CDI75114.1 - 0.73 8.5 4.6 0.82 8.3 3.2 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DUF3533 PF12051.3 CDI75114.1 - 0.83 8.3 3.5 0.91 8.2 2.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3533) PCNP PF15473.1 CDI75114.1 - 1 9.6 15.9 1.4 9.2 11.0 1.1 1 0 0 1 1 1 0 PEST, proteolytic signal-containing nuclear protein family DUF4551 PF15087.1 CDI75114.1 - 1.2 7.3 10.6 1.3 7.3 7.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) DUF566 PF04484.7 CDI75114.1 - 1.3 8.5 19.0 1.4 8.3 13.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF566) Hid1 PF12722.2 CDI75114.1 - 1.6 6.2 11.0 1.7 6.2 7.6 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Herpes_Helicase PF02689.9 CDI75114.1 - 1.8 6.2 5.5 0.21 9.3 0.1 1.7 1 1 1 2 2 2 0 Helicase AAA_28 PF13521.1 CDI75114.1 - 1.8 8.5 4.8 0.81 9.6 0.2 2.1 2 0 0 2 2 2 0 AAA domain DUF966 PF06136.8 CDI75114.1 - 2.4 7.4 16.7 2.7 7.3 11.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) DUF3337 PF11816.3 CDI75114.1 - 2.5 7.4 10.0 2.6 7.3 6.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3337) PsbQ PF05757.6 CDI75114.1 - 2.6 7.4 10.8 3.3 7.0 7.5 1.2 1 0 0 1 1 1 0 Oxygen evolving enhancer protein 3 (PsbQ) PsbW PF07123.7 CDI75114.1 - 3.1 7.8 15.0 4.7 7.2 10.4 1.2 1 0 0 1 1 1 0 Photosystem II reaction centre W protein (PsbW) PAP1 PF08601.5 CDI75114.1 - 3.2 7.3 20.3 3.4 7.2 14.1 1.0 1 0 0 1 1 1 0 Transcription factor PAP1 PPP4R2 PF09184.6 CDI75114.1 - 3.5 7.1 12.8 4.3 6.7 8.9 1.2 1 0 0 1 1 1 0 PPP4R2 TFIIA PF03153.8 CDI75114.1 - 3.5 7.4 16.9 3.6 7.3 11.7 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF2413 PF10310.4 CDI75114.1 - 6.4 5.4 18.5 6.3 5.4 12.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) DUF1675 PF07897.6 CDI75114.1 - 7.2 6.3 14.4 9 6.0 10.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) Rifin_STEVOR PF02009.11 CDI75114.1 - 7.2 6.1 9.0 8.7 5.8 6.2 1.1 1 0 0 1 1 1 0 Rifin/stevor family Peptidase_S64 PF08192.6 CDI75114.1 - 7.4 4.7 13.0 7.3 4.7 9.0 1.0 1 0 0 1 1 1 0 Peptidase family S64 CDC45 PF02724.9 CDI75114.1 - 8 4.3 11.1 7.8 4.3 7.7 1.1 1 0 0 1 1 1 0 CDC45-like protein PRP38_assoc PF12871.2 CDI75115.1 - 0.12 12.9 22.1 0.21 12.1 15.3 1.4 1 0 0 1 1 1 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term DUF1777 PF08648.7 CDI75115.1 - 7.2 6.3 30.2 25 4.5 20.9 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1777) WD40 PF00400.27 CDI75116.1 - 0.0058 16.4 10.0 0.19 11.6 0.5 4.0 5 0 0 5 5 5 2 WD domain, G-beta repeat PQQ_3 PF13570.1 CDI75116.1 - 0.071 13.4 1.2 13 6.2 0.2 3.8 4 1 0 4 4 4 0 PQQ-like domain DUF755 PF05501.6 CDI75117.1 - 0.0013 18.7 28.6 0.0013 18.7 19.8 8.1 7 1 1 8 8 8 1 Domain of unknown function (DUF755) CP12 PF02672.10 CDI75117.1 - 0.0036 17.7 4.1 0.0036 17.7 2.9 6.9 8 1 0 8 8 8 1 CP12 domain CT47 PF15623.1 CDI75118.1 - 0.086 12.5 6.0 0.1 12.2 4.2 1.0 1 0 0 1 1 1 0 Cancer/testis gene family 47 Spt20 PF12090.3 CDI75118.1 - 0.1 11.9 3.2 0.11 11.8 2.2 1.2 1 0 0 1 1 1 0 Spt20 family SAGA-Tad1 PF12767.2 CDI75118.1 - 0.12 12.0 7.8 0.13 11.8 5.4 1.1 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit MMR1 PF08505.5 CDI75118.1 - 0.16 11.9 5.5 0.2 11.6 3.8 1.0 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein Serinc PF03348.10 CDI75118.1 - 0.36 9.4 1.7 0.41 9.2 1.2 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) Rrn6 PF10214.4 CDI75118.1 - 1.1 7.3 7.1 1.1 7.2 4.9 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor DUF3759 PF12585.3 CDI75119.1 - 0.025 14.4 9.5 0.046 13.6 6.6 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3759) Trp_oprn_chp PF09534.5 CDI75119.1 - 0.14 11.7 4.2 0.17 11.4 2.9 1.1 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Herpes_glycop PF01528.11 CDI75119.1 - 0.93 8.1 3.0 1 8.0 2.1 1.1 1 0 0 1 1 1 0 Herpesvirus glycoprotein M DUF3357 PF11837.3 CDI75119.1 - 1.1 9.0 5.3 2.1 8.2 3.6 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF3357) FLO_LFY PF01698.11 CDI75119.1 - 1.2 7.8 13.8 1.4 7.6 9.6 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein Spore_coat_CotO PF14153.1 CDI75119.1 - 1.3 8.4 23.7 1.5 8.2 16.4 1.1 1 0 0 1 1 1 0 Spore coat protein CotO Herpes_UL87 PF03043.9 CDI75119.1 - 1.7 6.9 11.5 1.8 6.8 8.0 1.0 1 0 0 1 1 1 0 Herpesvirus UL87 family Tcf25 PF04910.9 CDI75119.1 - 1.7 7.5 10.8 2 7.2 7.5 1.1 1 0 0 1 1 1 0 Transcriptional repressor TCF25 DDHD PF02862.12 CDI75119.1 - 1.9 8.2 13.9 2.3 7.9 9.6 1.1 1 0 0 1 1 1 0 DDHD domain BTV_NS2 PF04514.7 CDI75119.1 - 1.9 7.2 11.9 2.2 7.0 8.3 1.0 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 FNIP_N PF14636.1 CDI75119.1 - 2 8.9 17.5 2.6 8.5 12.1 1.1 1 0 0 1 1 1 0 Folliculin-interacting protein N-terminus DUF4512 PF14975.1 CDI75119.1 - 2.2 9.1 9.1 4 8.3 6.3 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4512) HNOBA PF07701.9 CDI75119.1 - 2.4 7.3 19.4 19 4.3 13.8 1.8 1 1 1 2 2 2 0 Heme NO binding associated UPF0565 PF10561.4 CDI75119.1 - 2.4 6.9 11.2 3 6.6 7.7 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0565 DUF1675 PF07897.6 CDI75119.1 - 2.6 7.8 12.6 2.8 7.7 8.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) FAM60A PF15396.1 CDI75119.1 - 2.6 7.7 13.9 2.8 7.6 9.6 1.1 1 0 0 1 1 1 0 Protein Family FAM60A DUF3474 PF11960.3 CDI75119.1 - 2.8 7.9 7.2 3.4 7.7 5.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3474) Presenilin PF01080.12 CDI75119.1 - 3.3 6.4 11.7 3.5 6.3 8.1 1.0 1 0 0 1 1 1 0 Presenilin FTO_NTD PF12933.2 CDI75119.1 - 3.5 6.7 7.5 6.2 5.8 5.2 1.5 1 1 0 1 1 1 0 FTO catalytic domain Prog_receptor PF02161.10 CDI75119.1 - 3.8 6.2 11.7 4.4 6.0 8.1 1.0 1 0 0 1 1 1 0 Progesterone receptor DUF2126 PF09899.4 CDI75119.1 - 4.3 5.2 12.0 5.2 4.9 8.3 1.1 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) EF_assoc_2 PF08356.7 CDI75119.1 - 5.9 6.7 9.7 0.94 9.2 3.2 2.1 2 0 0 2 2 2 0 EF hand associated AUX_IAA PF02309.11 CDI75119.1 - 6.1 6.5 13.8 7.2 6.2 9.6 1.1 1 0 0 1 1 1 0 AUX/IAA family MRP-S26 PF14943.1 CDI75119.1 - 6.4 6.3 18.3 9.9 5.6 12.7 1.3 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 Neur_chan_memb PF02932.11 CDI75119.1 - 7.4 6.3 12.8 8.9 6.1 8.9 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region MDFI PF15316.1 CDI75119.1 - 9.1 6.2 11.9 11 5.9 8.2 1.1 1 0 0 1 1 1 0 MyoD family inhibitor NAM PF02365.10 CDI75120.1 - 0.32 11.1 10.9 0.47 10.6 7.6 1.3 1 0 0 1 1 1 0 No apical meristem (NAM) protein Raftlin PF15250.1 CDI75120.1 - 6.1 5.2 22.7 7.1 5.0 15.7 1.1 1 0 0 1 1 1 0 Raftlin PAT1 PF09770.4 CDI75121.1 - 7.4 4.6 54.9 1.1 7.4 28.1 2.2 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 SR-25 PF10500.4 CDI75122.1 - 0.016 14.7 9.3 0.016 14.6 6.4 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein CAF-1_p150 PF11600.3 CDI75122.1 - 0.22 10.8 3.6 0.23 10.8 2.5 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Gag_spuma PF03276.9 CDI75122.1 - 0.47 8.7 2.5 0.47 8.7 1.7 1.0 1 0 0 1 1 1 0 Spumavirus gag protein Macoilin PF09726.4 CDI75122.1 - 2.2 6.4 5.5 2.4 6.3 3.8 1.1 1 0 0 1 1 1 0 Transmembrane protein DUF515 PF04415.7 CDI75122.1 - 2.4 6.3 4.7 2.5 6.2 3.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Corona_nucleoca PF00937.13 CDI75122.1 - 4.3 6.1 6.7 4.8 6.0 4.6 1.0 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein Med15 PF09606.5 CDI75125.1 - 6.1e-05 21.4 42.5 6.1e-05 21.4 29.4 2.2 2 0 0 2 2 2 2 ARC105 or Med15 subunit of Mediator complex non-fungal Utp13 PF08625.6 CDI75125.1 - 0.00054 19.6 10.6 0.00054 19.6 7.3 4.1 1 1 2 3 3 3 1 Utp13 specific WD40 associated domain Ribosomal_60s PF00428.14 CDI75125.1 - 0.32 11.4 23.4 0.079 13.3 7.4 3.5 2 2 1 3 3 3 0 60s Acidic ribosomal protein Hid1 PF12722.2 CDI75125.1 - 1.3 6.6 41.1 0.1 10.2 13.3 2.1 2 0 0 2 2 2 0 High-temperature-induced dauer-formation protein SOBP PF15279.1 CDI75125.1 - 3.2 8.0 34.4 5 7.4 13.5 2.2 2 0 0 2 2 2 0 Sine oculis-binding protein eIF-3_zeta PF05091.7 CDI75125.1 - 3.6 6.1 41.4 0.26 9.8 12.3 2.1 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF853 PF05872.7 CDI75125.1 - 4 5.6 30.5 0.42 8.9 7.4 2.3 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF853) Raftlin PF15250.1 CDI75125.1 - 5.4 5.4 30.2 0.64 8.4 8.4 2.3 2 0 0 2 2 2 0 Raftlin DUF2362 PF10154.4 CDI75127.1 - 0.0018 17.0 17.1 0.0067 15.1 0.0 4.3 5 0 0 5 5 5 3 Uncharacterized conserved protein (DUF2362) Ank_2 PF12796.2 CDI75128.1 - 3.6e-08 33.6 0.3 2.3e-07 31.0 0.1 2.3 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 CDI75128.1 - 5.8e-05 23.4 0.1 0.00028 21.3 0.1 2.2 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.25 CDI75128.1 - 0.00011 21.8 0.5 0.023 14.4 0.1 3.3 1 1 1 2 2 2 1 Ankyrin repeat Ank_5 PF13857.1 CDI75128.1 - 0.00085 19.5 0.5 0.0052 16.9 0.2 2.6 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 CDI75128.1 - 0.019 15.1 0.9 0.2 11.9 0.0 3.1 3 0 0 3 3 3 0 Ankyrin repeat Methyltransf_26 PF13659.1 CDI75128.1 - 1.1 9.3 6.6 0.46 10.5 1.6 2.6 3 1 0 3 3 3 0 Methyltransferase domain Hepatitis_core PF00906.15 CDI75130.1 - 0.84 9.2 5.9 1.8 8.1 4.1 1.5 1 0 0 1 1 1 0 Hepatitis core antigen DENN PF02141.16 CDI75131.1 - 9.4e-20 71.1 7.2 9.4e-20 71.1 5.0 3.2 4 0 0 4 4 4 2 DENN (AEX-3) domain uDENN PF03456.13 CDI75131.1 - 3.2e-06 27.0 2.6 0.00052 19.9 0.0 3.5 3 0 0 3 3 3 2 uDENN domain Adeno_E1B_55K_N PF04623.7 CDI75132.1 - 1.5 9.3 4.9 0.47 10.9 0.7 2.1 2 0 0 2 2 2 0 Adenovirus E1B protein N-terminus Shadoo PF14999.1 CDI75133.1 - 0.00086 19.1 2.5 0.00096 19.0 1.7 1.1 1 0 0 1 1 1 1 Shadow of prion protein, neuroprotective RskA PF10099.4 CDI75133.1 - 0.072 12.8 7.6 0.09 12.5 5.3 1.2 1 0 0 1 1 1 0 Anti-sigma-K factor rskA DUF3450 PF11932.3 CDI75133.1 - 0.21 10.8 8.0 0.27 10.4 5.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Fusion_gly PF00523.13 CDI75133.1 - 8.5 4.3 9.5 8.9 4.2 6.6 1.1 1 0 0 1 1 1 0 Fusion glycoprotein F0 Activator_LAG-3 PF11498.3 CDI75134.1 - 0.00016 20.5 42.3 0.00016 20.5 29.3 8.0 5 1 3 8 8 8 3 Transcriptional activator LAG-3 VCBS PF13517.1 CDI75135.1 - 1.7e-22 79.5 8.6 2e-06 28.0 0.1 8.5 7 2 3 10 10 10 7 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.18 CDI75135.1 - 1e-20 72.7 20.6 4e-05 23.1 0.4 8.4 8 0 0 8 8 8 4 FG-GAP repeat FimP PF09766.4 CDI75135.1 - 1e-07 31.3 30.5 4.8e-05 22.6 1.1 3.2 3 0 0 3 3 3 3 Fms-interacting protein Spt20 PF12090.3 CDI75135.1 - 1.5e-05 24.4 24.8 0.0062 15.8 0.8 3.5 3 0 0 3 3 3 3 Spt20 family Med15 PF09606.5 CDI75135.1 - 0.00019 19.8 83.4 0.00099 17.4 9.9 3.4 3 0 0 3 3 3 3 ARC105 or Med15 subunit of Mediator complex non-fungal DUF4647 PF15504.1 CDI75135.1 - 0.0026 16.7 30.1 0.0078 15.1 1.5 3.1 3 0 0 3 3 3 2 Domain of unknown function (DUF4647) AAA_23 PF13476.1 CDI75135.1 - 0.0045 17.3 21.9 0.26 11.5 0.1 3.3 3 0 0 3 3 3 2 AAA domain zf-DHHC PF01529.15 CDI75135.1 - 0.0064 15.9 4.6 2.3 7.5 0.1 3.2 3 0 0 3 3 3 1 DHHC palmitoyltransferase CDK2AP PF09806.4 CDI75135.1 - 0.0095 16.1 11.7 0.0095 16.1 8.1 7.9 4 1 1 7 7 4 2 Cyclin-dependent kinase 2-associated protein EF-hand_1 PF00036.27 CDI75135.1 - 0.11 11.8 10.5 1.2 8.6 0.1 4.2 5 0 0 5 5 4 0 EF hand EF-hand_5 PF13202.1 CDI75135.1 - 0.21 10.9 11.6 3.8 7.0 0.2 4.0 4 0 0 4 4 3 0 EF hand PAT1 PF09770.4 CDI75135.1 - 0.22 9.6 64.8 0.53 8.4 8.0 3.1 3 0 0 3 3 3 0 Topoisomerase II-associated protein PAT1 EF-hand_7 PF13499.1 CDI75135.1 - 0.23 11.5 0.5 54 4.0 0.0 3.7 4 0 0 4 4 4 0 EF-hand domain pair RNA_lig_T4_1 PF09511.5 CDI75135.1 - 0.43 10.0 5.1 5.4 6.4 0.0 2.9 3 0 0 3 3 3 0 RNA ligase Plasmodium_Vir PF05795.6 CDI75135.1 - 0.45 9.6 25.2 0.87 8.7 2.0 3.2 2 1 1 3 3 3 0 Plasmodium vivax Vir protein Slu7 PF11708.3 CDI75135.1 - 0.69 9.6 23.9 0.021 14.5 0.9 3.3 3 0 0 3 3 3 0 Pre-mRNA splicing Prp18-interacting factor Spore_coat_CotO PF14153.1 CDI75135.1 - 0.81 9.1 31.1 0.079 12.3 3.0 3.4 3 0 0 3 3 3 0 Spore coat protein CotO MAT1 PF06391.8 CDI75135.1 - 6.2 6.3 37.9 0.088 12.3 1.8 3.2 3 0 0 3 3 3 0 CDK-activating kinase assembly factor MAT1 Serinc PF03348.10 CDI75135.1 - 7 5.2 18.4 6.5 5.3 2.6 3.3 3 0 0 3 3 3 0 Serine incorporator (Serinc) IncA PF04156.9 CDI75136.1 - 5e-05 22.9 8.0 5e-05 22.9 5.5 3.3 3 1 0 3 3 2 1 IncA protein FAM176 PF14851.1 CDI75136.1 - 0.0012 18.5 2.2 0.0012 18.5 1.5 2.3 2 0 0 2 2 2 1 FAM176 family DUF788 PF05620.6 CDI75136.1 - 0.0099 15.7 1.4 0.029 14.2 0.5 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF788) YfhO PF09586.5 CDI75136.1 - 0.016 13.2 2.1 0.021 12.8 1.5 1.2 1 0 0 1 1 1 0 Bacterial membrane protein YfhO Zip PF02535.17 CDI75136.1 - 0.067 12.1 1.5 0.11 11.4 1.0 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter SID-1_RNA_chan PF13965.1 CDI75136.1 - 0.21 9.7 7.6 0.25 9.4 3.5 1.9 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 TMEM51 PF15345.1 CDI75136.1 - 0.66 9.6 18.1 0.26 10.9 7.1 2.6 2 0 0 2 2 2 0 Transmembrane protein 51 DUF2232 PF09991.4 CDI75136.1 - 0.67 8.8 3.4 2.1 7.2 1.5 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2232) Ycf1 PF05758.7 CDI75136.1 - 1.2 6.7 13.2 2 6.0 9.1 1.4 1 1 0 1 1 1 0 Ycf1 DUF2215 PF10225.4 CDI75136.1 - 2.3 7.5 5.5 4.8 6.5 3.8 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) Mem_trans PF03547.13 CDI75136.1 - 2.4 6.3 8.2 4.2 5.5 5.7 1.4 1 0 0 1 1 1 0 Membrane transport protein Otopetrin PF03189.8 CDI75136.1 - 2.9 6.8 5.6 6.4 5.6 3.9 1.5 1 0 0 1 1 1 0 Otopetrin DUF1510 PF07423.6 CDI75136.1 - 6.3 6.0 24.5 0.23 10.8 7.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) OATP PF03137.15 CDI75136.1 - 6.8 4.6 8.2 1.2 7.0 3.1 1.5 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Renin_r PF07850.9 CDI75136.1 - 7.7 6.9 5.8 1.3 9.4 0.4 2.3 1 1 1 2 2 2 0 Renin receptor-like protein TFIIA PF03153.8 CDI75136.1 - 9.6 5.9 47.9 1.8 8.3 22.7 2.3 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Isy1 PF06246.7 CDI75137.1 - 0.072 12.4 14.7 0.35 10.2 5.4 2.2 2 0 0 2 2 2 0 Isy1-like splicing family Ribosomal_S26e PF01283.14 CDI75137.1 - 0.15 12.3 6.4 0.037 14.2 1.1 2.0 2 0 0 2 2 2 0 Ribosomal protein S26e CAAD PF14159.1 CDI75137.1 - 0.26 10.9 0.1 0.26 10.9 0.1 3.3 3 1 1 4 4 4 0 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase PNRC PF15365.1 CDI75137.1 - 6.6 6.8 20.1 13 5.9 5.0 3.4 3 0 0 3 3 3 0 Proline-rich nuclear receptor coactivator EF_TS PF00889.14 CDI75138.1 - 1.3e-26 93.3 15.0 3e-21 75.7 4.0 2.7 2 1 0 2 2 2 2 Elongation factor TS UBA PF00627.26 CDI75138.1 - 0.0081 15.9 0.0 0.0081 15.9 0.0 2.5 2 0 0 2 2 2 1 UBA/TS-N domain DUF572 PF04502.8 CDI75138.1 - 2.3 7.3 18.3 0.54 9.4 8.4 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF572) TSP9 PF11493.3 CDI75139.1 - 1.2 9.7 9.9 1.1 9.8 2.1 2.6 2 1 0 2 2 2 0 Thylakoid soluble phosphoprotein TSP9 DUF4482 PF14818.1 CDI75139.1 - 1.9 9.1 6.1 3.2 8.4 4.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4482) DUF2217 PF10265.4 CDI75139.1 - 2.1 6.9 5.6 2.7 6.6 3.9 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) RAP1 PF07218.6 CDI75139.1 - 3.2 5.7 11.9 4 5.4 8.2 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) FimP PF09766.4 CDI75140.1 - 0.0019 17.3 8.5 0.0019 17.3 5.9 8.0 7 1 1 8 8 8 5 Fms-interacting protein zf-DHHC PF01529.15 CDI75140.1 - 2.5 7.4 26.9 1.1 8.5 0.3 6.4 6 0 0 6 6 6 0 DHHC palmitoyltransferase PRA1 PF03208.14 CDI75141.1 - 0.063 12.6 0.3 0.36 10.1 0.1 2.2 2 0 0 2 2 2 0 PRA1 family protein SSP160 PF06933.6 CDI75143.1 - 0.04 11.9 24.3 0.05 11.5 16.8 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Macoilin PF09726.4 CDI75143.1 - 0.79 7.9 45.7 0.94 7.6 31.7 1.0 1 0 0 1 1 1 0 Transmembrane protein Na_trans_assoc PF06512.8 CDI75143.1 - 2.6 7.9 29.6 3.1 7.7 20.5 1.1 1 0 0 1 1 1 0 Sodium ion transport-associated ACDC PF14733.1 CDI75144.1 - 1.4e-15 57.1 0.1 2.8e-15 56.1 0.1 1.5 1 0 0 1 1 1 1 AP2-coincident C-terminal AP2 PF00847.15 CDI75144.1 - 1.2e-06 28.5 4.4 1.2e-06 28.5 3.1 2.2 2 0 0 2 2 2 1 AP2 domain TetR_C PF02909.12 CDI75144.1 - 0.019 14.6 0.5 0.1 12.2 0.7 2.0 2 0 0 2 2 2 0 Tetracyclin repressor, C-terminal all-alpha domain Transposase_22 PF02994.9 CDI75146.1 - 6 5.2 10.5 0.48 8.8 0.5 2.5 3 0 0 3 3 3 0 L1 transposable element DnaJ PF00226.26 CDI75147.1 - 5.4e-12 45.2 0.0 1.4e-11 43.9 0.0 1.7 1 0 0 1 1 1 1 DnaJ domain PITH PF06201.8 CDI75149.1 - 4.3e-21 75.2 0.0 7.2e-21 74.5 0.0 1.3 1 0 0 1 1 1 1 PITH domain Scs3p PF10261.4 CDI75151.1 - 6.1e-05 22.1 8.5 0.016 14.2 0.3 2.4 1 1 1 2 2 2 2 Inositol phospholipid synthesis and fat-storage-inducing TM Apt1 PF10351.4 CDI75151.1 - 6.3e-05 22.0 3.3 6.3e-05 22.0 2.3 2.1 2 0 0 2 2 2 1 Golgi-body localisation protein domain SPX PF03105.14 CDI75151.1 - 0.00014 21.7 0.3 0.00014 21.7 0.2 2.1 1 1 1 2 2 2 1 SPX domain ECH PF00378.15 CDI75151.1 - 0.0047 16.0 0.6 4.3 6.3 0.0 3.0 3 0 0 3 3 3 1 Enoyl-CoA hydratase/isomerase family YjeF_N PF03853.10 CDI75151.1 - 0.0066 16.0 0.2 3.5 7.2 0.0 2.7 3 0 0 3 3 3 2 YjeF-related protein N-terminus Pex14_N PF04695.8 CDI75151.1 - 0.015 15.3 27.7 0.099 12.6 2.2 3.3 2 1 1 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region SprA-related PF12118.3 CDI75151.1 - 0.018 14.3 32.5 0.011 15.1 12.1 2.2 2 0 0 2 2 2 0 SprA-related family MYCBPAP PF14646.1 CDI75151.1 - 0.044 12.4 20.3 0.048 12.3 1.9 2.8 2 1 1 3 3 3 0 MYCBP-associated protein family EIIBC-GUT_N PF03612.9 CDI75151.1 - 0.063 12.8 6.1 18 4.8 0.5 3.2 3 0 0 3 3 3 0 Sorbitol phosphotransferase enzyme II N-terminus Neocarzinostat PF00960.13 CDI75151.1 - 0.11 12.4 7.7 1.3 8.9 0.7 2.3 2 0 0 2 2 2 0 Neocarzinostatin family PBP1_TM PF14812.1 CDI75151.1 - 0.15 12.4 8.7 5.2 7.4 0.3 3.3 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF4604 PF15377.1 CDI75151.1 - 3.2 7.9 25.4 4.3 7.5 2.7 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4604) Tir_receptor_N PF07490.6 CDI75151.1 - 4 6.9 15.9 1.5 8.3 2.1 2.3 2 0 0 2 2 2 0 Translocated intimin receptor (Tir) N-terminus FAM60A PF15396.1 CDI75151.1 - 5 6.8 21.2 0.47 10.1 0.8 3.2 3 0 0 3 3 3 0 Protein Family FAM60A Pox_Ag35 PF03286.9 CDI75151.1 - 6.6 6.2 20.5 9.5 5.6 2.8 3.2 3 0 0 3 3 3 0 Pox virus Ag35 surface protein Herpes_gE PF02480.11 CDI75151.1 - 8.7 4.4 9.5 10 4.2 5.7 1.7 1 1 1 2 2 2 0 Alphaherpesvirus glycoprotein E Med15 PF09606.5 CDI75152.1 - 1.3e-05 23.7 62.7 1.4e-05 23.5 43.5 1.0 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal DUF1510 PF07423.6 CDI75152.1 - 0.0028 17.0 22.3 0.0033 16.8 15.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) MIP-T3 PF10243.4 CDI75152.1 - 0.0057 15.1 31.8 0.0065 15.0 22.0 1.1 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 SprA-related PF12118.3 CDI75152.1 - 0.014 14.7 52.7 0.019 14.2 36.5 1.2 1 0 0 1 1 1 0 SprA-related family PAT1 PF09770.4 CDI75152.1 - 0.047 11.9 51.3 0.054 11.7 35.5 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 U79_P34 PF03064.11 CDI75152.1 - 0.063 12.8 20.9 0.087 12.3 14.5 1.2 1 0 0 1 1 1 0 HSV U79 / HCMV P34 CAF-1_p150 PF11600.3 CDI75152.1 - 0.08 12.3 35.0 0.094 12.0 24.2 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Herpes_DNAp_acc PF04929.7 CDI75152.1 - 0.096 11.6 14.2 0.1 11.5 9.8 1.2 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Nop53 PF07767.6 CDI75152.1 - 0.16 10.9 34.0 0.17 10.8 23.5 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) DDHD PF02862.12 CDI75152.1 - 0.23 11.2 19.1 0.33 10.7 13.3 1.3 1 0 0 1 1 1 0 DDHD domain Raftlin PF15250.1 CDI75152.1 - 0.29 9.5 20.3 0.33 9.4 14.1 1.1 1 0 0 1 1 1 0 Raftlin Paramyxo_ncap PF00973.14 CDI75152.1 - 0.3 9.7 19.0 0.35 9.5 13.2 1.0 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein RR_TM4-6 PF06459.7 CDI75152.1 - 0.41 10.5 24.4 0.58 10.0 16.9 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SelP_N PF04592.9 CDI75152.1 - 0.43 9.9 28.4 0.62 9.3 19.7 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region DUF4045 PF13254.1 CDI75152.1 - 0.54 9.4 22.1 0.64 9.2 15.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) SAGA-Tad1 PF12767.2 CDI75152.1 - 0.62 9.6 25.0 0.69 9.5 17.3 1.1 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit Asp-B-Hydro_N PF05279.6 CDI75152.1 - 0.86 9.4 20.7 0.9 9.3 14.4 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region eIF-3_zeta PF05091.7 CDI75152.1 - 1.3 7.5 28.9 1.6 7.2 20.1 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) CDC45 PF02724.9 CDI75152.1 - 1.5 6.7 24.2 1.9 6.4 16.8 1.1 1 0 0 1 1 1 0 CDC45-like protein FAM60A PF15396.1 CDI75152.1 - 1.9 8.1 27.1 2.6 7.7 18.8 1.1 1 0 0 1 1 1 0 Protein Family FAM60A GAGA_bind PF06217.7 CDI75152.1 - 2.1 8.2 24.6 2.5 8.0 17.0 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family Ycf1 PF05758.7 CDI75152.1 - 2.4 5.7 27.3 2.7 5.6 19.0 1.0 1 0 0 1 1 1 0 Ycf1 CDK5_activator PF03261.10 CDI75152.1 - 2.5 7.3 18.0 2.8 7.2 12.5 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein SID-1_RNA_chan PF13965.1 CDI75152.1 - 3 5.8 12.3 3.6 5.6 8.5 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 RCR PF12273.3 CDI75152.1 - 3.3 8.2 27.5 4.4 7.8 19.0 1.2 1 0 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red FAM217 PF15344.1 CDI75152.1 - 4 6.9 28.0 5.6 6.4 19.4 1.1 1 0 0 1 1 1 0 FAM217 family DUF3523 PF12037.3 CDI75152.1 - 4.3 6.2 38.6 5 6.0 26.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3523) AUX_IAA PF02309.11 CDI75152.1 - 5.6 6.6 23.7 7.3 6.2 16.4 1.3 1 0 0 1 1 1 0 AUX/IAA family NARP1 PF12569.3 CDI75152.1 - 6 5.4 30.3 9.1 4.9 21.0 1.3 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Macoilin PF09726.4 CDI75152.1 - 6.4 4.9 24.6 9.3 4.3 17.1 1.3 1 0 0 1 1 1 0 Transmembrane protein PMSI1 PF15322.1 CDI75152.1 - 7.5 5.5 20.0 13 4.8 13.8 1.4 1 0 0 1 1 1 0 Protein missing in infertile sperm 1, putative Presenilin PF01080.12 CDI75152.1 - 8.3 5.1 16.1 10 4.8 11.2 1.2 1 0 0 1 1 1 0 Presenilin Apt1 PF10351.4 CDI75153.1 - 1.2 7.9 0.0 0.65 8.7 0.7 3.9 3 1 0 4 4 4 0 Golgi-body localisation protein domain Suf PF05843.9 CDI75154.1 - 0.0014 18.4 5.3 0.0014 18.4 3.7 2.1 2 0 0 2 2 2 1 Suppressor of forked protein (Suf) BRF1 PF07741.8 CDI75154.1 - 0.011 15.9 3.7 0.011 15.9 2.6 3.6 2 1 0 2 2 1 0 Brf1-like TBP-binding domain SAGA-Tad1 PF12767.2 CDI75154.1 - 0.47 10.0 13.4 0.022 14.4 3.6 2.1 2 0 0 2 2 2 0 Transcriptional regulator of RNA polII, SAGA, subunit DUF2215 PF10225.4 CDI75154.1 - 0.5 9.7 2.3 0.91 8.9 1.6 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) Peptidase_S49_N PF08496.5 CDI75154.1 - 0.63 9.8 11.3 0.029 14.1 2.4 2.3 2 0 0 2 2 2 0 Peptidase family S49 N-terminal DUF2232 PF09991.4 CDI75154.1 - 0.71 8.8 2.8 1.6 7.6 1.9 1.6 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) AAA_23 PF13476.1 CDI75154.1 - 0.86 9.8 12.0 0.1 12.8 4.1 2.0 2 0 0 2 2 2 0 AAA domain FNIP_N PF14636.1 CDI75154.1 - 1.3 9.4 9.6 0.14 12.6 1.5 2.4 2 0 0 2 2 2 0 Folliculin-interacting protein N-terminus RED_N PF07808.8 CDI75154.1 - 1.7 7.8 19.1 0.025 13.8 4.8 2.7 3 0 0 3 3 3 0 RED-like protein N-terminal region DUF2992 PF11208.3 CDI75154.1 - 2 8.3 19.6 1.3 8.9 9.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2992) OATP PF03137.15 CDI75154.1 - 5 5.0 5.0 0.53 8.2 0.6 1.4 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family DUF4557 PF15101.1 CDI75154.1 - 6.6 6.5 19.3 1.1 9.0 8.6 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4557) PAT1 PF09770.4 CDI75154.1 - 7.1 4.7 40.1 11 4.1 27.8 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Serinc PF03348.10 CDI75154.1 - 9.7 4.7 9.6 0.6 8.7 3.2 1.5 2 0 0 2 2 2 0 Serine incorporator (Serinc) Fe-ADH_2 PF13685.1 CDI75155.1 - 7.6 5.7 10.0 0.11 11.7 0.9 2.2 1 1 1 2 2 2 0 Iron-containing alcohol dehydrogenase FNIP_N PF14636.1 CDI75156.1 - 0.011 16.1 0.8 0.013 15.9 0.6 1.1 1 0 0 1 1 1 0 Folliculin-interacting protein N-terminus DUF533 PF04391.7 CDI75156.1 - 0.017 14.5 8.3 0.02 14.2 5.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF533) Bacillus_HBL PF05791.6 CDI75156.1 - 0.021 14.1 4.8 0.032 13.5 3.3 1.3 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) SprA-related PF12118.3 CDI75156.1 - 0.066 12.5 17.8 0.079 12.2 12.4 1.0 1 0 0 1 1 1 0 SprA-related family Peptidase_U57 PF05582.7 CDI75156.1 - 0.073 12.0 0.8 0.09 11.7 0.5 1.0 1 0 0 1 1 1 0 YabG peptidase U57 Spt20 PF12090.3 CDI75156.1 - 0.099 11.9 2.8 0.098 11.9 1.9 1.1 1 0 0 1 1 1 0 Spt20 family DUF3708 PF12501.3 CDI75156.1 - 0.1 12.4 3.3 0.12 12.1 2.3 1.1 1 0 0 1 1 1 0 Phosphate ATP-binding cassette transporter 2-ph_phosp PF04029.9 CDI75156.1 - 0.12 11.2 0.6 0.13 11.1 0.4 1.1 1 0 0 1 1 1 0 2-phosphosulpholactate phosphatase Prominin PF05478.6 CDI75156.1 - 0.24 8.9 4.1 0.29 8.6 2.9 1.0 1 0 0 1 1 1 0 Prominin Phage_GPO PF05929.6 CDI75156.1 - 0.3 10.2 5.3 0.35 10.0 3.6 1.0 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase DOR PF14839.1 CDI75156.1 - 0.6 9.8 9.8 0.71 9.5 6.8 1.0 1 0 0 1 1 1 0 DOR family HlyD PF00529.15 CDI75156.1 - 0.67 9.2 21.4 0.76 9.0 14.8 1.0 1 0 0 1 1 1 0 HlyD family secretion protein HlyD_2 PF12700.2 CDI75156.1 - 0.9 8.6 4.4 0.99 8.4 3.0 1.1 1 0 0 1 1 1 0 HlyD family secretion protein Med15 PF09606.5 CDI75156.1 - 0.95 7.5 17.6 1 7.4 12.2 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Androgen_recep PF02166.11 CDI75156.1 - 1 8.1 12.6 1.5 7.6 8.8 1.3 1 1 0 1 1 1 0 Androgen receptor Activator_LAG-3 PF11498.3 CDI75156.1 - 2.2 6.9 19.4 2.5 6.7 13.4 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 DivIC PF04977.10 CDI75156.1 - 7.3 6.1 12.8 32 4.1 7.2 2.2 2 0 0 2 2 2 0 Septum formation initiator Shadoo PF14999.1 CDI75156.1 - 9.7 6.0 9.3 0.19 11.5 0.8 1.8 1 1 1 2 2 2 0 Shadow of prion protein, neuroprotective SNase PF00565.12 CDI75158.1 - 4.4e-11 42.9 0.2 0.0025 18.0 0.0 4.9 4 1 0 4 4 4 3 Staphylococcal nuclease homologue Med15 PF09606.5 CDI75159.1 - 8e-05 21.0 64.8 8e-05 21.0 44.9 2.1 2 0 0 2 2 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal PAT1 PF09770.4 CDI75159.1 - 0.0035 15.6 53.7 0.0051 15.1 37.2 1.4 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 DUF4045 PF13254.1 CDI75159.1 - 0.079 12.2 22.3 0.11 11.8 15.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) DUF4175 PF13779.1 CDI75159.1 - 0.091 10.4 53.3 0.13 9.9 36.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) CDK5_activator PF03261.10 CDI75159.1 - 0.14 11.4 24.9 0.19 11.0 17.2 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein Mem_trans PF03547.13 CDI75159.1 - 0.3 9.3 6.8 0.45 8.7 4.7 1.3 1 0 0 1 1 1 0 Membrane transport protein PLRV_ORF5 PF01690.12 CDI75159.1 - 0.87 8.6 26.8 1.1 8.2 18.6 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein DUF4647 PF15504.1 CDI75159.1 - 0.93 8.2 31.3 1.1 8.0 21.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4647) HlyD_2 PF12700.2 CDI75159.1 - 1.3 8.1 20.9 1.7 7.7 14.5 1.1 1 0 0 1 1 1 0 HlyD family secretion protein Exonuc_VII_L PF02601.10 CDI75159.1 - 2.1 7.4 23.5 2.6 7.1 16.3 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF966 PF06136.8 CDI75159.1 - 3.3 7.0 22.4 4.4 6.6 15.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) DUF572 PF04502.8 CDI75159.1 - 3.9 6.6 28.5 4.8 6.3 19.7 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF572) SRP-alpha_N PF04086.8 CDI75159.1 - 4.1 6.6 26.2 5.2 6.3 18.1 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Macoilin PF09726.4 CDI75159.1 - 4.5 5.4 22.4 5.8 5.0 15.5 1.1 1 0 0 1 1 1 0 Transmembrane protein Herpes_UL87 PF03043.9 CDI75159.1 - 5.4 5.2 14.5 6.2 5.0 10.0 1.1 1 0 0 1 1 1 0 Herpesvirus UL87 family LMBR1 PF04791.11 CDI75159.1 - 5.9 5.3 9.4 6.5 5.2 6.5 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein SPX PF03105.14 CDI75159.1 - 7.1 6.3 21.5 8.9 5.9 14.9 1.1 1 0 0 1 1 1 0 SPX domain Asp-B-Hydro_N PF05279.6 CDI75159.1 - 7.3 6.3 24.4 9 6.0 16.9 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region PIG-S PF10510.4 CDI75159.1 - 8.3 4.9 23.8 12 4.4 16.5 1.2 1 0 0 1 1 1 0 Phosphatidylinositol-glycan biosynthesis class S protein Ank_2 PF12796.2 CDI75160.1 - 1.5e-16 60.5 1.5 8.3e-14 51.6 0.0 2.8 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.25 CDI75160.1 - 8.7e-14 50.5 0.7 1.7e-07 30.7 0.1 3.3 3 0 0 3 3 3 2 Ankyrin repeat Methyltransf_16 PF10294.4 CDI75160.1 - 3.1e-12 46.2 0.1 9.9e-11 41.3 0.0 2.5 1 1 0 1 1 1 1 Putative methyltransferase Ank_4 PF13637.1 CDI75160.1 - 3.6e-11 43.2 5.7 1.6e-06 28.4 0.1 3.7 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 CDI75160.1 - 1.3e-10 41.1 6.0 1e-06 28.7 0.1 3.9 2 2 2 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 CDI75160.1 - 4.5e-10 38.7 0.9 8.4e-06 25.5 0.0 3.7 3 0 0 3 3 3 2 Ankyrin repeat Methyltransf_23 PF13489.1 CDI75160.1 - 5.7e-07 29.3 0.0 5.7e-07 29.3 0.0 2.3 2 1 1 3 3 3 1 Methyltransferase domain Methyltransf_18 PF12847.2 CDI75160.1 - 0.0013 19.2 0.0 0.0013 19.2 0.0 2.8 3 0 0 3 3 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 CDI75160.1 - 0.0082 16.5 0.0 0.0082 16.5 0.0 3.6 3 1 0 3 3 2 1 Methyltransferase domain Ribosomal_60s PF00428.14 CDI75160.1 - 0.018 15.4 6.0 0.018 15.4 4.2 4.6 4 0 0 4 4 4 0 60s Acidic ribosomal protein MTS PF05175.9 CDI75160.1 - 0.038 13.3 2.4 0.046 13.1 0.0 2.4 2 0 0 2 2 2 0 Methyltransferase small domain RAB3GAP2_N PF14655.1 CDI75160.1 - 0.055 12.4 0.2 0.055 12.4 0.1 4.1 3 1 0 3 3 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus FGE-sulfatase PF03781.11 CDI75160.1 - 0.086 12.1 0.2 0.086 12.1 0.2 2.5 2 0 0 2 2 2 0 Sulfatase-modifying factor enzyme 1 DUF4350 PF14258.1 CDI75160.1 - 0.16 12.2 1.9 6.2 7.1 0.0 3.9 3 1 0 3 3 3 0 Domain of unknown function (DUF4350) Herpes_UL87 PF03043.9 CDI75160.1 - 0.2 10.0 15.3 0.88 7.8 9.2 2.3 1 1 0 1 1 1 0 Herpesvirus UL87 family DUF897 PF05982.7 CDI75160.1 - 0.24 10.1 4.6 0.054 12.2 0.4 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF897) Zip PF02535.17 CDI75160.1 - 0.3 10.0 2.6 0.95 8.4 1.8 1.9 1 0 0 1 1 1 0 ZIP Zinc transporter Ycf1 PF05758.7 CDI75160.1 - 0.41 8.3 13.0 0.038 11.7 5.1 1.9 2 0 0 2 2 2 0 Ycf1 Methyltransf_26 PF13659.1 CDI75160.1 - 0.5 10.4 0.0 0.5 10.4 0.0 4.5 2 1 0 2 2 1 0 Methyltransferase domain DUF1765 PF08578.5 CDI75161.1 - 3.8e-13 49.5 0.7 7.3e-13 48.6 0.5 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1765) F-box-like PF12937.2 CDI75162.1 - 1.2e-07 31.3 0.6 2.9e-07 30.1 0.0 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 CDI75162.1 - 0.00014 21.4 0.0 0.00077 19.0 0.0 2.2 2 0 0 2 2 2 1 F-box domain Cupin_5 PF06172.6 CDI75164.1 - 0.025 14.5 1.9 0.83 9.5 0.1 2.3 2 0 0 2 2 2 0 Cupin superfamily (DUF985) Spt20 PF12090.3 CDI75164.1 - 0.16 11.3 16.1 0.36 10.1 0.5 2.7 3 0 0 3 3 3 0 Spt20 family FimP PF09766.4 CDI75164.1 - 0.22 10.5 19.3 1.1 8.2 2.2 2.2 2 0 0 2 2 2 0 Fms-interacting protein RAB3GAP2_N PF14655.1 CDI75164.1 - 0.34 9.8 16.0 0.85 8.5 1.2 2.4 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus dsDNA_bind PF01984.15 CDI75164.1 - 0.48 10.4 33.7 0.81 9.7 8.8 2.9 2 0 0 2 2 2 0 Double-stranded DNA-binding domain AAA_23 PF13476.1 CDI75164.1 - 8.4 6.6 10.9 15 5.8 1.8 2.2 2 0 0 2 2 2 0 AAA domain MIP-T3 PF10243.4 CDI75165.1 - 0.00092 17.8 44.3 0.0011 17.4 30.7 1.0 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 Macoilin PF09726.4 CDI75165.1 - 0.13 10.5 41.5 0.18 10.0 28.8 1.1 1 0 0 1 1 1 0 Transmembrane protein DUF572 PF04502.8 CDI75165.1 - 2.5 7.2 40.3 3.8 6.6 27.9 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) Utp14 PF04615.8 CDI75165.1 - 3.8 5.5 42.6 4.8 5.2 29.5 1.0 1 0 0 1 1 1 0 Utp14 protein SR-25 PF10500.4 CDI75166.1 - 0.052 13.0 30.2 0.069 12.6 20.9 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF1510 PF07423.6 CDI75166.1 - 7.6 5.8 33.1 9.6 5.5 23.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DUF2126 PF09899.4 CDI75166.1 - 7.6 4.4 21.7 8.7 4.2 15.1 1.1 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) RR_TM4-6 PF06459.7 CDI75166.1 - 8.3 6.2 33.4 10 5.8 23.1 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Pox_Ag35 PF03286.9 CDI75166.1 - 9.1 5.7 22.2 11 5.4 15.4 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Kinesin PF00225.18 CDI75167.1 - 2.4e-85 286.2 6.8 1.1e-43 149.2 0.0 3.2 3 0 0 3 3 3 2 Kinesin motor domain FHA PF00498.21 CDI75167.1 - 0.0064 16.5 0.0 0.017 15.2 0.0 1.7 1 0 0 1 1 1 1 FHA domain AAA_13 PF13166.1 CDI75167.1 - 0.011 14.1 23.8 0.27 9.6 0.4 2.3 2 0 0 2 2 2 0 AAA domain IncA PF04156.9 CDI75167.1 - 1.7 8.2 37.7 0.16 11.5 15.4 2.6 2 1 0 2 2 2 0 IncA protein LMBR1 PF04791.11 CDI75167.1 - 2 6.9 5.6 4.3 5.8 3.9 1.5 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF1664 PF07889.7 CDI75167.1 - 4.9 6.9 13.4 1.4 8.7 5.3 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) AAA_23 PF13476.1 CDI75169.1 - 0.0028 17.9 6.5 0.0035 17.6 4.5 1.1 1 0 0 1 1 1 1 AAA domain DUF533 PF04391.7 CDI75169.1 - 0.072 12.4 19.5 0.1 11.9 9.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF533) Neur_chan_memb PF02932.11 CDI75169.1 - 0.63 9.8 11.7 0.84 9.4 8.1 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region ADP_ribosyl_GH PF03747.9 CDI75169.1 - 0.64 9.7 9.9 0.88 9.2 6.9 1.2 1 0 0 1 1 1 0 ADP-ribosylglycohydrolase Oleosin PF01277.12 CDI75169.1 - 0.94 9.0 5.0 0.8 9.2 1.2 2.0 2 0 0 2 2 2 0 Oleosin Macoilin PF09726.4 CDI75169.1 - 1.1 7.4 27.5 1.6 6.9 19.1 1.3 1 0 0 1 1 1 0 Transmembrane protein DUF2232 PF09991.4 CDI75169.1 - 1.6 7.6 8.3 0.89 8.4 2.7 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2232) DUF3373 PF11853.3 CDI75169.1 - 3.5 6.0 12.9 6 5.2 9.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) HA2 PF04408.18 CDI75169.1 - 3.5 7.6 6.9 2.7 8.0 1.6 2.1 2 0 0 2 2 2 0 Helicase associated domain (HA2) Cwf_Cwc_15 PF04889.7 CDI75169.1 - 4.3 6.9 21.8 0.29 10.8 1.8 2.1 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein SOBP PF15279.1 CDI75169.1 - 8.7 6.6 22.7 11 6.3 15.8 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein DUF4367 PF14285.1 CDI75170.1 - 0.024 13.9 4.6 0.082 12.2 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4367) DUF2339 PF10101.4 CDI75170.1 - 0.029 12.6 5.5 0.034 12.4 3.8 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2339) NicO PF03824.11 CDI75170.1 - 0.039 13.2 2.6 0.058 12.6 1.8 1.2 1 0 0 1 1 1 0 High-affinity nickel-transport protein SOBP PF15279.1 CDI75170.1 - 0.22 11.8 31.8 0.29 11.4 22.1 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein DUF2391 PF09622.5 CDI75170.1 - 0.92 8.6 7.3 1.5 7.8 5.0 1.4 1 1 0 1 1 1 0 Putative integral membrane protein (DUF2391) DUF92 PF01940.11 CDI75170.1 - 1.4 8.0 9.7 1.9 7.5 6.7 1.3 1 0 0 1 1 1 0 Integral membrane protein DUF92 Draxin PF15550.1 CDI75170.1 - 1.5 8.3 22.1 1.7 8.2 15.3 1.0 1 0 0 1 1 1 0 Draxin Abhydrolase_9_N PF15420.1 CDI75170.1 - 1.9 8.2 12.0 2.8 7.6 8.4 1.2 1 0 0 1 1 1 0 Alpha/beta-hydrolase family N-terminus APC_CDC26 PF10471.4 CDI75170.1 - 2.6 8.8 37.1 7.9 7.3 6.6 2.6 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit 1 DUF572 PF04502.8 CDI75170.1 - 2.8 7.0 19.5 3.5 6.7 13.5 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Peptidase_S64 PF08192.6 CDI75170.1 - 2.9 6.0 20.5 3.4 5.8 14.2 1.0 1 0 0 1 1 1 0 Peptidase family S64 SMN PF06003.7 CDI75170.1 - 7.4 5.5 19.6 13 4.8 13.6 1.3 1 1 0 1 1 1 0 Survival motor neuron protein (SMN) VIT1 PF01988.14 CDI75171.1 - 7.7e-06 25.5 1.2 9.3e-06 25.2 0.8 1.1 1 0 0 1 1 1 1 VIT family YbgS PF13985.1 CDI75171.1 - 0.00058 19.7 10.7 0.00085 19.2 7.4 1.3 1 0 0 1 1 1 1 YbgS-like protein Med15 PF09606.5 CDI75171.1 - 0.0015 16.8 40.9 0.0017 16.6 28.4 1.0 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal DUF605 PF04652.11 CDI75171.1 - 0.0049 16.3 22.7 0.0055 16.1 15.7 1.0 1 0 0 1 1 1 1 Vta1 like Peptidase_S49_N PF08496.5 CDI75171.1 - 0.0059 16.4 9.5 0.0075 16.0 6.6 1.1 1 0 0 1 1 1 1 Peptidase family S49 N-terminal DUF4557 PF15101.1 CDI75171.1 - 0.0094 15.8 18.1 0.013 15.3 12.6 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4557) Suf PF05843.9 CDI75171.1 - 0.014 15.1 15.0 0.017 14.8 10.4 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Spore_coat_CotO PF14153.1 CDI75171.1 - 0.018 14.4 18.9 0.021 14.2 13.1 1.1 1 0 0 1 1 1 0 Spore coat protein CotO MRP-S31 PF15433.1 CDI75171.1 - 0.027 13.9 18.2 0.033 13.6 12.6 1.0 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 Activator_LAG-3 PF11498.3 CDI75171.1 - 0.034 12.9 38.9 0.043 12.5 27.0 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Macoilin PF09726.4 CDI75171.1 - 0.037 12.3 20.2 0.046 12.0 14.0 1.1 1 0 0 1 1 1 0 Transmembrane protein Raftlin PF15250.1 CDI75171.1 - 0.064 11.7 13.5 0.065 11.7 9.3 1.1 1 0 0 1 1 1 0 Raftlin CKAP2_C PF15297.1 CDI75171.1 - 0.068 11.9 13.6 0.071 11.9 9.4 1.1 1 0 0 1 1 1 0 Cytoskeleton-associated protein 2 C-terminus HemX PF04375.9 CDI75171.1 - 0.07 11.7 25.6 0.083 11.4 17.7 1.0 1 0 0 1 1 1 0 HemX FHIPEP PF00771.15 CDI75171.1 - 0.073 11.3 5.2 0.11 10.8 3.6 1.3 1 0 0 1 1 1 0 FHIPEP family Ycf1 PF05758.7 CDI75171.1 - 0.098 10.3 12.2 0.11 10.2 8.5 1.0 1 0 0 1 1 1 0 Ycf1 RR_TM4-6 PF06459.7 CDI75171.1 - 0.12 12.2 11.3 0.14 12.0 7.8 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DDRGK PF09756.4 CDI75171.1 - 0.13 11.6 18.3 0.16 11.3 12.7 1.1 1 0 0 1 1 1 0 DDRGK domain Gag_spuma PF03276.9 CDI75171.1 - 0.13 10.5 25.0 0.14 10.4 17.3 1.1 1 0 0 1 1 1 0 Spumavirus gag protein MMR1 PF08505.5 CDI75171.1 - 0.14 12.1 21.1 0.17 11.9 14.6 1.1 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein PPP4R2 PF09184.6 CDI75171.1 - 0.17 11.4 12.7 0.19 11.2 8.8 1.1 1 0 0 1 1 1 0 PPP4R2 TFIIA PF03153.8 CDI75171.1 - 0.18 11.6 33.4 0.22 11.4 23.1 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SprA-related PF12118.3 CDI75171.1 - 0.2 10.9 38.1 0.26 10.6 26.4 1.1 1 0 0 1 1 1 0 SprA-related family Parvo_coat PF00740.13 CDI75171.1 - 0.22 10.4 22.0 0.25 10.2 15.2 1.0 1 0 0 1 1 1 0 Parvovirus coat protein VP2 Peptidase_S15 PF02129.13 CDI75171.1 - 0.25 10.7 12.2 0.33 10.3 8.4 1.1 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) PBP_sp32 PF07222.7 CDI75171.1 - 0.27 10.3 18.6 0.32 10.1 12.9 1.1 1 0 0 1 1 1 0 Proacrosin binding protein sp32 CDK5_activator PF03261.10 CDI75171.1 - 0.27 10.5 14.3 0.31 10.3 9.9 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein Hex_IIIa PF02455.11 CDI75171.1 - 0.28 9.8 13.7 0.33 9.5 9.5 1.0 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) Dicty_REP PF05086.7 CDI75171.1 - 0.28 8.8 18.8 0.33 8.6 13.0 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Peptidase_S64 PF08192.6 CDI75171.1 - 0.34 9.2 14.8 0.39 9.0 10.3 1.0 1 0 0 1 1 1 0 Peptidase family S64 DUF1387 PF07139.6 CDI75171.1 - 0.37 10.3 11.1 0.44 10.1 7.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) Sec62 PF03839.11 CDI75171.1 - 0.38 10.1 7.7 0.41 10.0 5.4 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 DUF2215 PF10225.4 CDI75171.1 - 0.43 9.9 7.9 0.51 9.7 5.5 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) MSP1_C PF07462.6 CDI75171.1 - 0.46 8.8 9.8 0.55 8.5 6.8 1.1 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus DUF1510 PF07423.6 CDI75171.1 - 0.47 9.7 17.5 0.54 9.5 12.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DDHD PF02862.12 CDI75171.1 - 0.59 9.8 15.0 0.69 9.6 10.4 1.1 1 0 0 1 1 1 0 DDHD domain RNA_pol_Rpb1_5 PF04998.12 CDI75171.1 - 0.62 9.2 13.2 0.76 8.9 9.1 1.1 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 DUF3260 PF11658.3 CDI75171.1 - 0.72 7.9 10.2 0.9 7.6 7.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3260) DUF2048 PF09752.4 CDI75171.1 - 0.75 8.6 8.2 0.53 9.0 4.6 1.5 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2048) SPX PF03105.14 CDI75171.1 - 0.78 9.4 16.1 0.91 9.2 11.1 1.1 1 0 0 1 1 1 0 SPX domain AUX_IAA PF02309.11 CDI75171.1 - 0.8 9.4 12.9 0.94 9.1 9.0 1.2 1 0 0 1 1 1 0 AUX/IAA family FLO_LFY PF01698.11 CDI75171.1 - 0.98 8.1 18.7 1.1 7.9 13.0 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein DUF4045 PF13254.1 CDI75171.1 - 1.1 8.4 17.0 1.3 8.2 11.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) SGIII PF15467.1 CDI75171.1 - 1.1 8.2 12.1 1.3 8.0 8.4 1.0 1 0 0 1 1 1 0 Secretogranin-3 RP-C_C PF11800.3 CDI75171.1 - 1.1 8.8 16.0 1.4 8.5 11.1 1.2 1 0 0 1 1 1 0 Replication protein C C-terminal region DUF4220 PF13968.1 CDI75171.1 - 1.4 7.9 9.6 1.6 7.7 6.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4220) PAT1 PF09770.4 CDI75171.1 - 1.5 6.9 38.2 1.7 6.8 26.5 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 FAM60A PF15396.1 CDI75171.1 - 1.6 8.4 15.6 1.9 8.1 10.8 1.1 1 0 0 1 1 1 0 Protein Family FAM60A Serinc PF03348.10 CDI75171.1 - 1.6 7.3 13.0 2.2 6.8 9.0 1.3 1 0 0 1 1 1 0 Serine incorporator (Serinc) SID-1_RNA_chan PF13965.1 CDI75171.1 - 1.7 6.7 6.3 1.8 6.6 4.4 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 HGTP_anticodon2 PF12745.2 CDI75171.1 - 1.7 7.6 15.0 2.1 7.4 10.4 1.2 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs Hid1 PF12722.2 CDI75171.1 - 1.8 6.1 18.7 1.9 6.0 12.9 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Paramyxo_ncap PF00973.14 CDI75171.1 - 2.1 6.9 15.7 2.4 6.7 10.9 1.0 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein IncA PF04156.9 CDI75171.1 - 2.1 7.8 17.8 3.4 7.2 12.3 1.5 1 1 0 1 1 1 0 IncA protein DUF3984 PF13136.1 CDI75171.1 - 2.2 7.4 20.4 2.7 7.1 14.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3984) BTV_NS2 PF04514.7 CDI75171.1 - 2.3 7.0 12.7 2.5 6.8 8.8 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Herpes_TAF50 PF03326.8 CDI75171.1 - 2.8 6.8 25.9 3.1 6.6 17.9 1.0 1 0 0 1 1 1 0 Herpesvirus transcription activation factor (transactivator) DUF4446 PF14584.1 CDI75171.1 - 3 7.6 6.2 4.6 7.0 4.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) Presenilin PF01080.12 CDI75171.1 - 3.4 6.3 14.0 3.7 6.2 9.7 1.1 1 0 0 1 1 1 0 Presenilin LMBR1 PF04791.11 CDI75171.1 - 3.5 6.0 8.5 3.8 5.9 5.9 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein NHS PF15273.1 CDI75171.1 - 3.6 6.0 21.2 4.4 5.8 14.7 1.0 1 0 0 1 1 1 0 NHS-like CPSF100_C PF13299.1 CDI75171.1 - 4.3 7.4 18.8 5.8 7.0 13.0 1.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal FAM217 PF15344.1 CDI75171.1 - 4.5 6.7 19.1 5.4 6.4 13.2 1.1 1 0 0 1 1 1 0 FAM217 family DUF913 PF06025.7 CDI75171.1 - 5.6 5.6 11.9 6.1 5.4 8.2 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Hom_end_hint PF05203.11 CDI75171.1 - 5.7 6.6 13.4 7 6.3 9.3 1.3 1 0 0 1 1 1 0 Hom_end-associated Hint Ndc1_Nup PF09531.5 CDI75171.1 - 5.9 5.1 12.1 6.3 5.0 8.4 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup HCO3_cotransp PF00955.16 CDI75171.1 - 6.5 5.2 10.3 16 4.0 7.1 1.7 1 1 0 1 1 1 0 HCO3- transporter family Neur_chan_memb PF02932.11 CDI75171.1 - 7.1 6.4 17.7 8.5 6.1 12.3 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Cellulose_synt PF03552.9 CDI75171.1 - 7.3 4.7 6.7 7.9 4.6 4.7 1.1 1 0 0 1 1 1 0 Cellulose synthase RCR PF12273.3 CDI75171.1 - 8.1 7.0 21.3 9.7 6.7 14.8 1.3 1 0 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red DUF1275 PF06912.6 CDI75173.1 - 0.00085 18.5 0.4 0.0014 17.8 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) BatA PF07584.6 CDI75173.1 - 0.076 13.2 0.5 0.076 13.2 0.3 3.4 3 2 1 4 4 4 0 Aerotolerance regulator N-terminal SAGA-Tad1 PF12767.2 CDI75174.1 - 3.6 7.1 32.2 4.3 6.9 22.3 1.1 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit Daxx PF03344.10 CDI75174.1 - 5.9 5.2 44.6 7 5.0 30.9 1.0 1 0 0 1 1 1 0 Daxx Family UPF0564 PF10595.4 CDI75175.1 - 0.0013 17.6 6.2 0.0013 17.6 4.3 5.9 5 1 0 5 5 5 2 Uncharacterised protein family UPF0564 ApbE PF02424.10 CDI75176.1 - 1 8.6 7.2 1.2 8.4 5.0 1.0 1 0 0 1 1 1 0 ApbE family DUF1183 PF06682.7 CDI75176.1 - 1.7 8.1 14.4 2.2 7.8 10.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) Rtf2 PF04641.7 CDI75176.1 - 3.2 6.8 13.4 4.1 6.5 9.3 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger AUX_IAA PF02309.11 CDI75176.1 - 3.7 7.2 11.8 4.5 6.9 8.2 1.2 1 0 0 1 1 1 0 AUX/IAA family DUF1675 PF07897.6 CDI75176.1 - 4.2 7.1 13.4 4.9 6.9 9.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) DDHD PF02862.12 CDI75176.1 - 4.5 7.0 14.4 5.8 6.6 10.0 1.1 1 0 0 1 1 1 0 DDHD domain Glyco_hydro_1 PF00232.13 CDI75176.1 - 4.7 5.2 10.0 4.7 5.2 6.9 1.0 1 0 0 1 1 1 0 Glycosyl hydrolase family 1 Herpes_DNAp_acc PF04929.7 CDI75176.1 - 5.2 5.9 15.6 5.6 5.8 10.8 1.0 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Lipoprotein_X PF03305.8 CDI75176.1 - 5.2 6.3 11.3 6 6.1 7.8 1.1 1 0 0 1 1 1 0 Mycoplasma MG185/MG260 protein DUF3449 PF11931.3 CDI75176.1 - 5.4 6.4 15.9 7.3 6.0 11.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3449) FAM60A PF15396.1 CDI75176.1 - 6.1 6.5 14.1 7.1 6.3 9.8 1.1 1 0 0 1 1 1 0 Protein Family FAM60A FLO_LFY PF01698.11 CDI75176.1 - 7.7 5.2 15.4 8.5 5.1 10.7 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein TRM13 PF05206.9 CDI75176.1 - 9.7 5.3 11.1 14 4.8 7.7 1.2 1 0 0 1 1 1 0 Methyltransferase TRM13 GETHR PF05671.6 CDI75178.1 - 0.00064 18.8 11.9 0.00064 18.8 8.2 7.2 2 2 3 5 5 5 2 GETHR pentapeptide repeat (5 copies) ERGIC_N PF13850.1 CDI75179.1 - 0.019 14.9 0.4 0.087 12.8 0.3 2.1 1 0 0 1 1 1 0 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) NGP1NT PF08153.7 CDI75180.1 - 1.8e-34 118.4 0.3 1.1e-33 115.9 0.0 2.4 2 1 0 2 2 2 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.18 CDI75180.1 - 3.4e-17 62.4 0.0 4.7e-14 52.3 0.0 2.4 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.13 CDI75180.1 - 1.2e-05 24.6 0.0 0.004 16.4 0.0 2.4 2 0 0 2 2 2 2 Ferrous iron transport protein B GTP_EFTU PF00009.22 CDI75180.1 - 6.1e-05 22.5 0.1 0.0013 18.2 0.0 2.5 1 1 1 3 3 3 1 Elongation factor Tu GTP binding domain Arf PF00025.16 CDI75180.1 - 0.00014 21.1 0.1 0.24 10.6 0.0 2.3 2 0 0 2 2 2 2 ADP-ribosylation factor family DUF258 PF03193.11 CDI75180.1 - 0.0015 17.7 0.0 0.0027 16.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Dynamin_N PF00350.18 CDI75180.1 - 0.013 15.3 0.2 3.4 7.4 0.0 3.0 2 1 1 3 3 3 0 Dynamin family Beta-Casp PF10996.3 CDI75181.1 - 1.5e-18 66.9 0.0 5e-18 65.2 0.0 1.8 2 0 0 2 2 2 1 Beta-Casp domain RMMBL PF07521.7 CDI75181.1 - 4.7e-11 42.3 0.1 1.1e-10 41.1 0.0 1.7 2 0 0 2 2 2 1 RNA-metabolising metallo-beta-lactamase Lactamase_B_2 PF12706.2 CDI75181.1 - 4.3e-07 29.6 0.0 2.8e-06 27.0 0.0 2.2 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 CDI75181.1 - 8.8e-07 28.7 0.2 5e-05 23.0 0.0 3.2 3 1 0 3 3 3 1 Metallo-beta-lactamase superfamily Cpn60_TCP1 PF00118.19 CDI75182.1 - 1.6e-103 346.9 0.0 2.8e-103 346.1 0.0 1.4 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family SecA_SW PF07516.8 CDI75182.1 - 0.025 14.3 1.5 0.069 12.8 1.0 1.7 1 1 0 1 1 1 0 SecA Wing and Scaffold domain DUF1192 PF06698.6 CDI75182.1 - 0.32 10.8 2.2 9.9 6.0 0.0 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1192) DNA_primase_lrg PF04104.9 CDI75182.1 - 0.74 9.0 3.4 2.3 7.3 0.2 2.2 1 1 1 2 2 2 0 Eukaryotic and archaeal DNA primase, large subunit Mnd1 PF03962.10 CDI75182.1 - 1.7 8.3 6.5 77 2.8 0.4 2.4 1 1 1 2 2 2 0 Mnd1 family Aminotran_1_2 PF00155.16 CDI75183.1 - 1.9e-38 132.3 0.0 3e-38 131.7 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 CDI75183.1 - 0.00029 19.2 0.0 0.00043 18.6 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme OKR_DC_1 PF01276.15 CDI75183.1 - 0.0004 19.0 0.1 0.0016 17.0 0.0 1.8 1 1 0 1 1 1 1 Orn/Lys/Arg decarboxylase, major domain DegT_DnrJ_EryC1 PF01041.12 CDI75183.1 - 0.0012 17.9 2.0 0.15 11.0 1.4 3.1 2 1 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.16 CDI75183.1 - 0.0065 15.6 0.0 0.011 14.8 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase ORC6 PF05460.8 CDI75184.1 - 0.3 10.1 8.6 0.37 9.8 6.0 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) YL1 PF05764.8 CDI75184.1 - 1.3 8.5 13.2 1.6 8.2 9.2 1.1 1 0 0 1 1 1 0 YL1 nuclear protein DUF2393 PF09624.5 CDI75186.1 - 0.01 15.3 0.5 0.01 15.3 0.4 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2393) Plant_all_beta PF10532.4 CDI75186.1 - 0.016 15.2 0.2 0.025 14.6 0.1 1.2 1 0 0 1 1 1 0 Plant specific N-all beta domain Condensation PF00668.15 CDI75186.1 - 0.03 13.1 10.8 0.036 12.9 7.5 1.1 1 0 0 1 1 1 0 Condensation domain CDC73 PF05179.9 CDI75186.1 - 0.26 10.6 6.0 0.34 10.2 4.2 1.2 1 0 0 1 1 1 0 RNA pol II accessory factor, Cdc73 family EpoR_lig-bind PF09067.5 CDI75186.1 - 0.45 10.5 2.8 0.89 9.5 1.7 1.6 2 0 0 2 2 2 0 Erythropoietin receptor, ligand binding UPF0542 PF15086.1 CDI75186.1 - 0.63 9.7 3.8 1 9.1 0.7 2.2 2 0 0 2 2 2 0 Uncharacterised protein family UPF0542 TP53IP5 PF15331.1 CDI75186.1 - 0.83 9.5 7.1 1 9.2 4.9 1.1 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 BAF1_ABF1 PF04684.8 CDI75186.1 - 2.7 6.7 17.3 4.3 6.0 12.0 1.3 1 1 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor DUF1098 PF06497.6 CDI75186.1 - 4.7 7.3 7.5 0.49 10.4 2.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1098) PAT1 PF09770.4 CDI75186.1 - 4.7 5.3 21.4 5.2 5.1 14.8 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 YfhO PF09586.5 CDI75186.1 - 6.1 4.7 5.5 6.9 4.5 3.8 1.0 1 0 0 1 1 1 0 Bacterial membrane protein YfhO SprA-related PF12118.3 CDI75187.1 - 0.0046 16.3 21.9 0.0046 16.3 15.2 10.9 5 3 3 8 8 8 2 SprA-related family PAT1 PF09770.4 CDI75189.1 - 0.0011 17.3 37.5 0.0011 17.3 26.0 1.1 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 Ycf1 PF05758.7 CDI75189.1 - 0.0016 16.2 7.4 0.0016 16.2 5.1 1.0 1 0 0 1 1 1 1 Ycf1 Peptidase_S49_N PF08496.5 CDI75189.1 - 0.0026 17.5 8.9 0.0031 17.2 6.2 1.3 1 0 0 1 1 1 1 Peptidase family S49 N-terminal SAGA-Tad1 PF12767.2 CDI75189.1 - 0.0028 17.3 14.0 0.0029 17.3 9.7 1.1 1 0 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit Raftlin PF15250.1 CDI75189.1 - 0.0033 16.0 10.2 0.0034 15.9 7.1 1.0 1 0 0 1 1 1 1 Raftlin Med15 PF09606.5 CDI75189.1 - 0.0059 14.8 58.5 0.0081 14.4 40.6 1.2 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal DDHD PF02862.12 CDI75189.1 - 0.013 15.3 13.9 0.015 15.1 9.6 1.2 1 0 0 1 1 1 0 DDHD domain Serinc PF03348.10 CDI75189.1 - 0.015 14.0 11.5 0.018 13.7 8.0 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) Mnd1 PF03962.10 CDI75189.1 - 0.016 14.8 16.8 0.026 14.2 11.6 1.3 1 0 0 1 1 1 0 Mnd1 family Plasmodium_Vir PF05795.6 CDI75189.1 - 0.018 14.2 3.6 0.021 14.0 2.5 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein AUX_IAA PF02309.11 CDI75189.1 - 0.025 14.3 13.2 0.029 14.1 9.2 1.1 1 0 0 1 1 1 0 AUX/IAA family Parvo_coat PF00740.13 CDI75189.1 - 0.04 12.8 16.7 0.042 12.8 11.5 1.0 1 0 0 1 1 1 0 Parvovirus coat protein VP2 Anoctamin PF04547.7 CDI75189.1 - 0.046 12.3 4.6 0.045 12.4 3.2 1.2 1 0 0 1 1 1 0 Calcium-activated chloride channel Pilt PF15453.1 CDI75189.1 - 0.054 13.1 16.4 0.062 12.9 11.4 1.1 1 0 0 1 1 1 0 Protein incorporated later into Tight Junctions GAGA_bind PF06217.7 CDI75189.1 - 0.071 13.0 11.9 0.075 12.9 8.3 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family UPF0118 PF01594.11 CDI75189.1 - 0.078 11.9 0.1 0.087 11.8 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function DUF20 Spc7_N PF15402.1 CDI75189.1 - 0.13 10.3 22.0 0.16 9.9 15.2 1.1 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 Tim54 PF11711.3 CDI75189.1 - 0.13 10.8 9.1 0.14 10.6 6.3 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 eIF-3_zeta PF05091.7 CDI75189.1 - 0.13 10.9 21.9 0.14 10.7 15.1 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) SID-1_RNA_chan PF13965.1 CDI75189.1 - 0.13 10.4 6.2 0.14 10.3 4.3 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 SpoIIP PF07454.6 CDI75189.1 - 0.14 11.2 11.2 0.18 10.9 7.8 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) DUF913 PF06025.7 CDI75189.1 - 0.15 10.8 8.4 0.17 10.5 5.8 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DUF4557 PF15101.1 CDI75189.1 - 0.18 11.6 27.4 0.25 11.1 19.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) Hamartin PF04388.7 CDI75189.1 - 0.22 10.1 11.6 0.23 10.1 8.0 1.1 1 0 0 1 1 1 0 Hamartin protein Cyto_heme_lyase PF01265.12 CDI75189.1 - 0.25 10.8 14.6 0.28 10.7 10.1 1.2 1 0 0 1 1 1 0 Cytochrome c/c1 heme lyase MRP-S31 PF15433.1 CDI75189.1 - 0.26 10.6 18.2 0.34 10.2 12.6 1.2 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 FAM176 PF14851.1 CDI75189.1 - 0.27 10.8 7.1 0.38 10.4 4.9 1.3 1 0 0 1 1 1 0 FAM176 family PPP4R2 PF09184.6 CDI75189.1 - 0.3 10.5 13.4 0.36 10.3 9.3 1.1 1 0 0 1 1 1 0 PPP4R2 GOLD_2 PF13897.1 CDI75189.1 - 0.32 11.2 3.7 0.46 10.7 2.5 1.3 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking CDC45 PF02724.9 CDI75189.1 - 0.33 8.9 13.4 0.37 8.7 9.3 1.1 1 0 0 1 1 1 0 CDC45-like protein Neur_chan_memb PF02932.11 CDI75189.1 - 0.39 10.5 9.2 0.46 10.3 6.3 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Activator_LAG-3 PF11498.3 CDI75189.1 - 0.53 8.9 54.7 0.8 8.3 37.9 1.3 1 0 0 1 1 1 0 Transcriptional activator LAG-3 DUF2048 PF09752.4 CDI75189.1 - 0.53 9.1 11.2 0.8 8.5 7.7 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2048) PH_4 PF15404.1 CDI75189.1 - 0.53 9.7 11.2 0.73 9.3 7.8 1.3 1 0 0 1 1 1 0 Pleckstrin homology domain TFIIA PF03153.8 CDI75189.1 - 0.54 10.1 40.9 0.67 9.7 28.3 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SeqA PF03925.8 CDI75189.1 - 0.58 9.8 15.2 0.74 9.4 10.6 1.2 1 0 0 1 1 1 0 SeqA protein YABBY PF04690.8 CDI75189.1 - 0.69 10.1 10.6 0.97 9.6 7.3 1.3 1 0 0 1 1 1 0 YABBY protein CPSF100_C PF13299.1 CDI75189.1 - 0.7 10.0 14.3 0.85 9.7 9.9 1.3 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal RR_TM4-6 PF06459.7 CDI75189.1 - 0.72 9.6 18.5 0.92 9.3 12.8 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Spore_coat_CotO PF14153.1 CDI75189.1 - 0.74 9.2 24.6 0.91 8.9 17.0 1.1 1 0 0 1 1 1 0 Spore coat protein CotO BORG_CEP PF14957.1 CDI75189.1 - 0.75 10.7 12.6 1 10.2 8.8 1.2 1 0 0 1 1 1 0 Cdc42 effector FAM60A PF15396.1 CDI75189.1 - 0.78 9.4 14.6 0.96 9.1 10.1 1.1 1 0 0 1 1 1 0 Protein Family FAM60A DUF106 PF01956.11 CDI75189.1 - 0.81 9.2 12.2 1.1 8.7 8.5 1.3 1 0 0 1 1 1 0 Integral membrane protein DUF106 Dicty_REP PF05086.7 CDI75189.1 - 0.84 7.3 11.6 0.94 7.1 8.0 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF2126 PF09899.4 CDI75189.1 - 0.87 7.5 12.6 0.99 7.3 8.7 1.1 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) Endonuc_Holl PF10107.4 CDI75189.1 - 0.9 9.2 15.1 1.1 8.9 10.5 1.2 1 0 0 1 1 1 0 Endonuclease related to archaeal Holliday junction resolvase DUF2215 PF10225.4 CDI75189.1 - 0.93 8.8 10.5 1.2 8.4 7.3 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) SPX PF03105.14 CDI75189.1 - 0.95 9.1 17.0 1.1 8.9 11.8 1.1 1 0 0 1 1 1 0 SPX domain Herpes_DNAp_acc PF04929.7 CDI75189.1 - 1.1 8.0 11.9 1.3 7.9 8.3 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor FLO_LFY PF01698.11 CDI75189.1 - 1.3 7.8 17.5 1.6 7.4 12.1 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein DUF4011 PF13195.1 CDI75189.1 - 1.3 9.0 12.1 1.6 8.7 8.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4011) Peptidase_S64 PF08192.6 CDI75189.1 - 1.3 7.2 16.9 1.6 6.9 11.7 1.0 1 0 0 1 1 1 0 Peptidase family S64 Herpes_glycop PF01528.11 CDI75189.1 - 1.4 7.5 10.8 2.2 6.8 7.5 1.4 1 1 0 1 1 1 0 Herpesvirus glycoprotein M DUF4045 PF13254.1 CDI75189.1 - 1.6 7.9 17.5 2 7.5 12.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Cellulose_synt PF03552.9 CDI75189.1 - 1.7 6.8 7.4 2 6.6 5.1 1.1 1 0 0 1 1 1 0 Cellulose synthase Pal1 PF08316.6 CDI75189.1 - 1.8 9.0 11.2 3.3 8.1 7.8 1.5 1 0 0 1 1 1 0 Pal1 cell morphology protein Het-C PF07217.6 CDI75189.1 - 1.8 6.6 11.3 2.1 6.4 7.8 1.1 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C APG6 PF04111.7 CDI75189.1 - 1.9 7.4 22.0 2.1 7.2 15.3 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Pex16 PF08610.5 CDI75189.1 - 1.9 7.3 17.8 2.6 6.9 12.3 1.1 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) AMP-binding PF00501.23 CDI75189.1 - 2.3 6.5 6.3 2.8 6.2 4.3 1.1 1 0 0 1 1 1 0 AMP-binding enzyme Paramyxo_ncap PF00973.14 CDI75189.1 - 2.4 6.7 15.5 3 6.4 10.7 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein DUF2232 PF09991.4 CDI75189.1 - 2.6 6.9 12.9 4.7 6.1 8.9 1.5 1 1 0 1 1 1 0 Predicted membrane protein (DUF2232) Hom_end_hint PF05203.11 CDI75189.1 - 2.7 7.6 11.9 3.6 7.2 8.2 1.2 1 0 0 1 1 1 0 Hom_end-associated Hint Baculo_PP31 PF05311.6 CDI75189.1 - 3 7.0 17.2 3.7 6.7 12.0 1.2 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) Gti1_Pac2 PF09729.4 CDI75189.1 - 3.1 7.6 12.8 4.2 7.2 8.9 1.2 1 0 0 1 1 1 0 Gti1/Pac2 family DUF342 PF03961.8 CDI75189.1 - 3.3 6.0 12.0 3.8 5.8 8.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Presenilin PF01080.12 CDI75189.1 - 3.7 6.2 16.3 4.5 6.0 11.3 1.1 1 0 0 1 1 1 0 Presenilin Ctr PF04145.10 CDI75189.1 - 3.8 7.5 16.0 6.3 6.8 11.0 1.5 1 1 0 1 1 1 0 Ctr copper transporter family DHHW PF14286.1 CDI75189.1 - 4.3 6.5 15.7 5 6.3 10.9 1.1 1 0 0 1 1 1 0 DHHW protein FemAB PF02388.11 CDI75189.1 - 4.5 5.8 19.3 6.3 5.3 13.3 1.2 1 0 0 1 1 1 0 FemAB family DUF4106 PF13388.1 CDI75189.1 - 4.9 6.0 34.3 5.4 5.8 23.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) Glyco_transf_15 PF01793.11 CDI75189.1 - 5.2 5.9 16.7 6.9 5.5 11.6 1.1 1 0 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase Spore_YhcN_YlaJ PF09580.5 CDI75189.1 - 5.5 7.0 16.8 7.7 6.5 11.6 1.2 1 0 0 1 1 1 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) Gryzun PF07919.7 CDI75189.1 - 6.2 5.0 19.3 9.9 4.3 13.4 1.3 1 0 0 1 1 1 0 Gryzun, putative trafficking through Golgi CDK5_activator PF03261.10 CDI75189.1 - 6.3 6.0 17.2 8.1 5.6 11.9 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein Band_3_cyto PF07565.8 CDI75189.1 - 6.4 6.2 21.2 8.4 5.8 14.7 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Paf1 PF03985.8 CDI75189.1 - 6.4 5.4 22.3 7.8 5.1 15.4 1.1 1 0 0 1 1 1 0 Paf1 Bestrophin PF01062.16 CDI75189.1 - 7.3 5.4 9.0 9.5 5.0 6.2 1.2 1 0 0 1 1 1 0 Bestrophin, RFP-TM, chloride channel MMR1 PF08505.5 CDI75189.1 - 8.4 6.3 24.8 11 5.9 17.2 1.2 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein Hid1 PF12722.2 CDI75189.1 - 8.7 3.8 21.2 10 3.6 14.7 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein LMBR1 PF04791.11 CDI75189.1 - 9.4 4.6 7.2 9.9 4.6 5.0 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Bud13 PF09736.4 CDI75189.1 - 9.4 6.4 25.4 13 6.0 17.6 1.2 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex Neur_chan_memb PF02932.11 CDI75190.1 - 0.15 11.8 11.4 1.2 9.0 3.8 2.3 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Band_3_cyto PF07565.8 CDI75190.1 - 0.23 10.9 24.8 0.067 12.7 5.7 2.3 2 0 0 2 2 2 0 Band 3 cytoplasmic domain Ycf1 PF05758.7 CDI75190.1 - 0.76 7.4 21.5 0.021 12.6 1.9 2.0 2 0 0 2 2 2 0 Ycf1 SAGA-Tad1 PF12767.2 CDI75190.1 - 1.1 8.8 32.4 0.04 13.5 9.8 2.3 2 0 0 2 2 2 0 Transcriptional regulator of RNA polII, SAGA, subunit DUF1269 PF06897.7 CDI75190.1 - 2 8.4 12.7 0.3 11.1 0.1 3.8 2 1 0 3 3 3 0 Protein of unknown function (DUF1269) Draxin PF15550.1 CDI75190.1 - 2.9 7.4 17.2 2 8.0 0.6 2.3 2 0 0 2 2 2 0 Draxin DUF4407 PF14362.1 CDI75190.1 - 7 5.5 38.4 0.18 10.7 7.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Linocin_M18 PF04454.7 CDI75191.1 - 0.12 11.2 0.2 0.15 10.9 0.1 1.1 1 0 0 1 1 1 0 Encapsulating protein for peroxidase TraG-D_C PF12696.2 CDI75191.1 - 5.1 6.9 15.4 0.85 9.4 0.7 2.4 2 0 0 2 2 2 0 TraM recognition site of TraD and TraG DUF966 PF06136.8 CDI75191.1 - 9.1 5.5 23.1 11 5.3 16.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Med15 PF09606.5 CDI75192.1 - 1.4 7.0 38.6 1.5 6.8 26.7 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal PRKCSH_1 PF13015.1 CDI75193.1 - 0.092 12.2 0.0 5.7 6.3 0.0 2.3 2 0 0 2 2 2 0 Glucosidase II beta subunit-like protein SNF PF00209.13 CDI75194.1 - 0.00024 19.7 2.8 0.00033 19.2 0.0 2.1 2 1 0 2 2 2 1 Sodium:neurotransmitter symporter family IQ PF00612.22 CDI75195.1 - 0.38 10.5 7.1 15 5.5 3.6 2.5 2 0 0 2 2 2 0 IQ calmodulin-binding motif SF-assemblin PF06705.6 CDI75197.1 - 1.6e-28 99.5 15.7 2.2e-20 72.8 6.0 2.0 1 1 1 2 2 2 2 SF-assemblin/beta giardin LUC7 PF03194.10 CDI75197.1 - 0.0068 15.9 9.7 0.033 13.7 0.8 2.3 1 1 1 2 2 2 2 LUC7 N_terminus Apolipoprotein PF01442.13 CDI75197.1 - 0.1 12.0 17.1 0.41 10.1 0.1 2.7 2 1 0 2 2 2 0 Apolipoprotein A1/A4/E domain FUSC-like PF12805.2 CDI75197.1 - 0.62 8.9 6.2 0.41 9.5 3.3 1.4 1 1 0 1 1 1 0 FUSC-like inner membrane protein yccS Acetyltransf_1 PF00583.19 CDI75197.1 - 0.72 9.9 4.2 0.92 9.5 1.4 2.2 1 1 1 2 2 2 0 Acetyltransferase (GNAT) family DUF445 PF04286.7 CDI75197.1 - 0.9 9.0 8.7 1.5 8.2 0.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF445) zf-C2H2 PF00096.21 CDI75198.1 - 1.1e-05 25.4 0.4 2.1e-05 24.5 0.2 1.5 1 0 0 1 1 1 1 Zinc finger, C2H2 type XPA_N PF01286.13 CDI75198.1 - 0.0028 17.3 0.1 0.0046 16.5 0.1 1.2 1 0 0 1 1 1 1 XPA protein N-terminal zf-C2H2_4 PF13894.1 CDI75198.1 - 0.011 15.9 0.2 0.025 14.8 0.1 1.6 1 0 0 1 1 1 0 C2H2-type zinc finger Prefoldin_2 PF01920.15 CDI75198.1 - 0.078 12.7 14.2 0.17 11.6 8.3 2.6 1 1 1 2 2 2 0 Prefoldin subunit DUF3533 PF12051.3 CDI75198.1 - 6.1 5.4 7.0 9 4.9 4.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3533) MORN PF02493.15 CDI75200.1 - 4.2e-12 45.0 28.5 1.7e-05 24.2 0.5 6.2 6 0 0 6 6 6 5 MORN repeat GCC2_GCC3 PF07699.8 CDI75204.1 - 0.002 17.6 0.9 0.002 17.6 0.6 28.6 16 9 9 26 26 26 18 GCC2 and GCC3 tRNA-synt_2 PF00152.15 CDI75205.1 - 5.6e-87 291.6 0.0 8.2e-87 291.0 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 CDI75205.1 - 5.8e-10 38.8 0.0 1.2e-09 37.8 0.0 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 CDI75205.1 - 3.5e-08 32.9 0.0 2.1e-05 23.8 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) tRNA-synt_2b PF00587.20 CDI75205.1 - 0.00078 19.0 0.1 0.19 11.3 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetase class II core domain (G, H, P, S and T) GCR1_C PF12550.3 CDI75205.1 - 0.03 14.1 1.0 0.22 11.3 0.0 2.8 4 0 0 4 4 4 0 Transcriptional activator of glycolytic enzymes NARP1 PF12569.3 CDI75205.1 - 0.59 8.8 7.4 0.89 8.2 5.1 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 rve PF00665.21 CDI75206.1 - 9.4e-05 22.5 0.0 0.00012 22.1 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain DUF1662 PF07878.6 CDI75209.1 - 0.072 12.8 0.1 1.4 8.6 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1662) Kelch_4 PF13418.1 CDI75211.1 - 5e-19 67.8 5.2 2.8e-09 36.6 0.1 3.5 3 0 0 3 3 3 3 Galactose oxidase, central domain Kelch_5 PF13854.1 CDI75211.1 - 2.6e-10 40.0 1.4 0.00068 19.5 0.0 3.5 3 0 0 3 3 3 2 Kelch motif Kelch_3 PF13415.1 CDI75211.1 - 3e-09 36.7 8.6 0.00091 19.3 0.1 3.5 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_1 PF01344.20 CDI75211.1 - 2.7e-08 33.2 2.7 0.011 15.2 0.0 3.3 3 0 0 3 3 3 3 Kelch motif Kelch_6 PF13964.1 CDI75211.1 - 1.6e-05 24.8 4.3 0.14 12.3 0.1 3.4 2 1 1 3 3 3 2 Kelch motif Kelch_2 PF07646.10 CDI75211.1 - 0.0039 16.8 2.5 1.4 8.7 0.1 3.4 3 0 0 3 3 3 1 Kelch motif EGF_2 PF07974.8 CDI75211.1 - 2.4 8.3 10.0 5.7 7.1 6.9 1.7 1 0 0 1 1 1 0 EGF-like domain Pex14_N PF04695.8 CDI75213.1 - 0.077 13.0 9.6 0.089 12.8 6.6 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region FAM60A PF15396.1 CDI75213.1 - 0.081 12.6 8.0 0.1 12.3 5.6 1.1 1 0 0 1 1 1 0 Protein Family FAM60A CDK2AP PF09806.4 CDI75213.1 - 0.085 13.0 13.6 0.12 12.5 9.4 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein Herpes_capsid PF06112.6 CDI75213.1 - 0.13 12.2 17.5 0.14 12.2 12.1 1.2 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein GEMIN8 PF15348.1 CDI75213.1 - 0.23 11.4 7.7 0.27 11.2 5.3 1.1 1 0 0 1 1 1 0 Gemini of Cajal bodies-associated protein 8 DUF2201_N PF13203.1 CDI75213.1 - 0.25 10.4 7.8 0.31 10.1 5.4 1.0 1 0 0 1 1 1 0 Putative metallopeptidase domain RAP1 PF07218.6 CDI75213.1 - 0.36 8.8 21.7 0.38 8.7 15.0 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) HGTP_anticodon2 PF12745.2 CDI75213.1 - 0.36 9.9 12.6 0.45 9.6 8.7 1.0 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs BicD PF09730.4 CDI75213.1 - 0.38 9.0 9.1 0.44 8.8 6.3 1.0 1 0 0 1 1 1 0 Microtubule-associated protein Bicaudal-D Sec3_C PF09763.4 CDI75213.1 - 0.45 8.6 12.4 0.5 8.4 8.6 1.0 1 0 0 1 1 1 0 Exocyst complex component Sec3 DHHW PF14286.1 CDI75213.1 - 0.5 9.6 7.5 0.58 9.4 5.2 1.0 1 0 0 1 1 1 0 DHHW protein CAF-1_p150 PF11600.3 CDI75213.1 - 0.61 9.4 20.3 0.83 8.9 14.1 1.3 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal TCP PF03634.8 CDI75213.1 - 0.77 10.1 13.4 0.92 9.8 9.3 1.1 1 0 0 1 1 1 0 TCP family transcription factor Apt1 PF10351.4 CDI75213.1 - 0.85 8.4 20.0 0.97 8.2 13.8 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Lin-8 PF03353.10 CDI75213.1 - 0.88 8.7 7.4 1 8.5 5.1 1.0 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Macoilin PF09726.4 CDI75213.1 - 0.9 7.7 22.8 1 7.5 15.8 1.0 1 0 0 1 1 1 0 Transmembrane protein SprA-related PF12118.3 CDI75213.1 - 0.93 8.7 15.1 1 8.6 10.5 1.1 1 0 0 1 1 1 0 SprA-related family Period_C PF12114.3 CDI75213.1 - 1.1 8.8 22.5 1.3 8.5 15.6 1.2 1 0 0 1 1 1 0 Period protein 2/3C-terminal region DUF515 PF04415.7 CDI75213.1 - 1.1 7.4 19.9 1.2 7.3 13.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) DUF789 PF05623.7 CDI75213.1 - 1.3 8.3 8.9 1.6 8.1 6.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF789) DUF605 PF04652.11 CDI75213.1 - 1.6 8.0 11.1 1.7 7.9 7.7 1.1 1 0 0 1 1 1 0 Vta1 like DUF1675 PF07897.6 CDI75213.1 - 1.7 8.4 15.7 2.1 8.1 10.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) SSP160 PF06933.6 CDI75213.1 - 1.9 6.3 29.9 2.2 6.1 20.8 1.0 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Ndc1_Nup PF09531.5 CDI75213.1 - 2.2 6.6 11.5 2.3 6.5 8.0 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup AF-4 PF05110.8 CDI75213.1 - 2.2 6.0 31.4 2.1 6.0 21.8 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Sox_N PF12444.3 CDI75213.1 - 2.4 9.3 18.2 3.9 8.6 12.6 1.3 1 0 0 1 1 1 0 Sox developmental protein N terminal PPP4R2 PF09184.6 CDI75213.1 - 2.6 7.5 12.9 2.8 7.4 9.0 1.1 1 0 0 1 1 1 0 PPP4R2 CDC45 PF02724.9 CDI75213.1 - 3 5.7 12.4 3.3 5.6 8.6 1.0 1 0 0 1 1 1 0 CDC45-like protein Mcm10 PF09332.6 CDI75213.1 - 3.4 6.9 10.6 4 6.6 7.3 1.0 1 0 0 1 1 1 0 Mcm10 replication factor DUF2146 PF10220.4 CDI75213.1 - 3.9 5.3 12.2 4.6 5.0 8.5 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2146) Kei1 PF08552.6 CDI75213.1 - 4.4 6.9 5.7 4.9 6.7 4.0 1.3 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 Paramyxo_C PF01692.13 CDI75213.1 - 5 6.6 10.3 5.8 6.4 7.1 1.1 1 0 0 1 1 1 0 Paramyxovirus non-structural protein c Corona_nucleoca PF00937.13 CDI75213.1 - 5.2 5.9 19.5 6.4 5.6 13.5 1.2 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein DNA_pol_viral_N PF00242.12 CDI75213.1 - 5.6 5.8 17.1 6.2 5.7 11.8 1.1 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain CytochromB561_N PF09786.4 CDI75213.1 - 6.2 5.1 15.7 6.6 5.0 10.9 1.0 1 0 0 1 1 1 0 Cytochrome B561, N terminal DDHD PF02862.12 CDI75213.1 - 6.6 6.4 14.3 7.5 6.2 9.9 1.1 1 0 0 1 1 1 0 DDHD domain DUF2217 PF10265.4 CDI75213.1 - 6.8 5.3 17.7 7.2 5.2 12.2 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) Na_trans_assoc PF06512.8 CDI75213.1 - 7.2 6.5 13.9 8.8 6.2 9.7 1.1 1 0 0 1 1 1 0 Sodium ion transport-associated Peptidase_S64 PF08192.6 CDI75213.1 - 8.8 4.5 15.3 10 4.2 10.6 1.0 1 0 0 1 1 1 0 Peptidase family S64 YajC PF02699.10 CDI75214.1 - 0.025 14.2 0.3 0.03 13.9 0.2 1.1 1 0 0 1 1 1 0 Preprotein translocase subunit Pentapeptide PF00805.17 CDI75215.1 - 1.8e-10 39.7 3.3 0.29 10.4 0.0 6.8 1 1 8 10 10 10 5 Pentapeptide repeats (8 copies) Pentapeptide_4 PF13599.1 CDI75215.1 - 0.0033 17.1 0.0 1.4 8.7 0.0 2.9 1 1 2 3 3 3 2 Pentapeptide repeats (9 copies) CfAFP PF05264.6 CDI75215.1 - 0.011 15.4 0.6 2.8 7.6 0.1 2.6 1 1 1 2 2 2 0 Choristoneura fumiferana antifreeze protein (CfAFP) GTP_EFTU_D4 PF14578.1 CDI75215.1 - 0.094 12.3 39.0 6.1 6.5 0.3 7.5 1 1 2 3 3 3 0 Elongation factor Tu domain 4 Nop14 PF04147.7 CDI75216.1 - 0.058 11.3 36.2 0.059 11.2 25.1 1.0 1 0 0 1 1 1 0 Nop14-like family DUF4337 PF14235.1 CDI75216.1 - 0.086 12.6 2.7 0.11 12.3 1.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Spore_coat_CotO PF14153.1 CDI75216.1 - 0.34 10.3 23.1 0.37 10.1 16.0 1.1 1 0 0 1 1 1 0 Spore coat protein CotO SDA1 PF05285.7 CDI75216.1 - 0.42 9.8 33.1 0.44 9.7 22.9 1.0 1 0 0 1 1 1 0 SDA1 CENP-T PF15511.1 CDI75216.1 - 0.89 8.7 24.3 0.87 8.7 16.8 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Tim54 PF11711.3 CDI75216.1 - 1.6 7.2 12.2 1.9 7.0 8.5 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Glypican PF01153.14 CDI75216.1 - 1.8 7.0 7.4 2 6.9 5.2 1.0 1 0 0 1 1 1 0 Glypican Plasmodium_Vir PF05795.6 CDI75216.1 - 2.7 7.1 9.3 3.5 6.7 6.4 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein CKAP2_C PF15297.1 CDI75216.1 - 3.3 6.4 15.0 3.4 6.3 10.4 1.1 1 0 0 1 1 1 0 Cytoskeleton-associated protein 2 C-terminus CDC45 PF02724.9 CDI75216.1 - 5.2 4.9 23.3 5.6 4.8 16.1 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF913 PF06025.7 CDI75216.1 - 6 5.4 5.8 6.4 5.4 4.0 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Raftlin PF15250.1 CDI75216.1 - 6.4 5.1 11.2 6.9 5.0 7.7 1.0 1 0 0 1 1 1 0 Raftlin DDRGK PF09756.4 CDI75216.1 - 7.6 5.8 27.4 11 5.3 19.0 1.2 1 0 0 1 1 1 0 DDRGK domain BUD22 PF09073.5 CDI75216.1 - 8 5.4 32.8 8.4 5.3 22.7 1.1 1 0 0 1 1 1 0 BUD22 F_actin_cap_B PF01115.12 CDI75217.1 - 3.3e-26 91.9 0.0 5.3e-26 91.2 0.0 1.2 1 0 0 1 1 1 1 F-actin capping protein, beta subunit DUF3337 PF11816.3 CDI75217.1 - 0.023 14.0 0.1 0.03 13.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3337) Macoilin PF09726.4 CDI75217.1 - 9.2 4.4 9.4 14 3.8 6.5 1.2 1 0 0 1 1 1 0 Transmembrane protein Spt20 PF12090.3 CDI75218.1 - 0.44 9.8 7.5 0.22 10.8 0.7 2.1 2 0 0 2 2 2 0 Spt20 family DUF3357 PF11837.3 CDI75218.1 - 4 7.3 8.9 9.5 6.1 0.4 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF3357) Mucin PF01456.12 CDI75218.1 - 4.1 7.1 19.4 7.8 6.2 13.5 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein AAA_23 PF13476.1 CDI75219.1 - 3.4 7.9 86.9 0.094 13.0 8.5 4.1 4 0 0 4 4 4 0 AAA domain PAT1 PF09770.4 CDI75221.1 - 2.2 6.4 33.7 0.016 13.5 16.4 2.0 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 Ndc1_Nup PF09531.5 CDI75222.1 - 0.0027 16.2 7.4 0.0031 15.9 5.1 1.2 1 0 0 1 1 1 1 Nucleoporin protein Ndc1-Nup Peptidase_S64 PF08192.6 CDI75222.1 - 0.021 13.2 12.9 0.023 13.0 9.0 1.0 1 0 0 1 1 1 0 Peptidase family S64 CobN-Mg_chel PF02514.11 CDI75222.1 - 0.048 11.0 0.8 0.059 10.7 0.6 1.0 1 0 0 1 1 1 0 CobN/Magnesium Chelatase DUF566 PF04484.7 CDI75222.1 - 0.28 10.6 20.6 0.34 10.3 14.3 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF566) Mem_trans PF03547.13 CDI75222.1 - 0.47 8.6 6.4 0.53 8.5 4.4 1.1 1 0 0 1 1 1 0 Membrane transport protein Macoilin PF09726.4 CDI75222.1 - 0.49 8.6 27.2 0.6 8.3 18.9 1.1 1 0 0 1 1 1 0 Transmembrane protein Presenilin PF01080.12 CDI75222.1 - 0.66 8.7 13.2 0.92 8.2 9.1 1.2 1 0 0 1 1 1 0 Presenilin Raftlin PF15250.1 CDI75222.1 - 1.2 7.5 10.4 1.5 7.2 7.2 1.1 1 0 0 1 1 1 0 Raftlin DUF605 PF04652.11 CDI75222.1 - 1.6 8.0 17.0 1.9 7.7 11.8 1.1 1 0 0 1 1 1 0 Vta1 like Sec3_C PF09763.4 CDI75222.1 - 1.6 6.7 12.9 2.7 6.0 9.0 1.3 1 0 0 1 1 1 0 Exocyst complex component Sec3 CytochromB561_N PF09786.4 CDI75222.1 - 2.5 6.4 21.4 2.8 6.2 14.8 1.0 1 0 0 1 1 1 0 Cytochrome B561, N terminal AvrE PF11725.3 CDI75222.1 - 2.5 5.0 13.2 2.9 4.8 9.2 1.0 1 0 0 1 1 1 0 Pathogenicity factor Utp14 PF04615.8 CDI75222.1 - 2.7 6.0 11.2 3.1 5.8 7.8 1.0 1 0 0 1 1 1 0 Utp14 protein Cnd1_N PF12922.2 CDI75222.1 - 3 7.4 11.1 4.8 6.7 0.4 2.2 1 1 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1, N-term DUF1675 PF07897.6 CDI75222.1 - 3.7 7.3 18.6 4.8 6.9 12.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) Hydrolase_3 PF08282.7 CDI75224.1 - 1.8e-36 126.0 0.0 1.1e-21 77.5 0.0 2.0 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase S6PP PF05116.8 CDI75224.1 - 5.7e-07 29.0 0.0 0.00033 20.0 0.0 2.2 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase Hydrolase PF00702.21 CDI75224.1 - 0.0031 17.9 1.0 0.97 9.8 0.2 2.7 2 1 1 3 3 3 2 haloacid dehalogenase-like hydrolase HAD PF12710.2 CDI75224.1 - 0.0078 16.4 1.2 0.27 11.3 0.8 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Clathrin_bdg PF15045.1 CDI75224.1 - 0.11 12.0 0.0 0.22 11.0 0.0 1.4 1 0 0 1 1 1 0 Clathrin-binding box of Aftiphilin, vesicle trafficking DUF572 PF04502.8 CDI75226.1 - 0.014 14.6 26.9 0.022 13.9 18.7 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) ASFV_J13L PF05568.6 CDI75227.1 - 7 6.1 8.2 3.4 7.1 3.2 2.1 2 0 0 2 2 2 0 African swine fever virus J13L protein Med15 PF09606.5 CDI75228.1 - 0.016 13.4 41.9 0.019 13.1 29.0 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Ketoacyl-synt_2 PF13723.1 CDI75228.1 - 0.073 12.3 6.1 0.1 11.8 4.2 1.3 1 0 0 1 1 1 0 Beta-ketoacyl synthase, N-terminal domain PAT1 PF09770.4 CDI75228.1 - 1.4 7.0 38.1 1.6 6.8 26.4 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TFIIA PF03153.8 CDI75228.1 - 1.5 8.6 19.7 1.8 8.3 13.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit AP2 PF00847.15 CDI75229.1 - 2e-07 31.0 0.2 2e-07 31.0 0.2 2.8 3 0 0 3 3 3 1 AP2 domain SAGA-Tad1 PF12767.2 CDI75232.1 - 0.05 13.2 13.1 0.057 13.0 9.1 1.1 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit Protocadherin PF08374.6 CDI75232.1 - 0.11 12.0 5.8 0.13 11.9 4.1 1.2 1 0 0 1 1 1 0 Protocadherin DUF2457 PF10446.4 CDI75232.1 - 0.13 10.9 7.2 0.15 10.7 5.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DUF2115 PF09888.4 CDI75232.1 - 0.22 11.6 4.2 0.31 11.1 2.9 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2115) IncA PF04156.9 CDI75232.1 - 0.23 11.0 26.7 0.32 10.5 18.5 1.2 1 0 0 1 1 1 0 IncA protein SAPS PF04499.10 CDI75232.1 - 0.73 8.3 9.0 0.84 8.2 6.2 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Glyco_hydro_1 PF00232.13 CDI75232.1 - 0.88 7.6 5.6 1 7.4 3.9 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 1 AbiH PF14253.1 CDI75232.1 - 0.9 9.0 4.4 1.1 8.7 3.0 1.1 1 0 0 1 1 1 0 Bacteriophage abortive infection AbiH Band_3_cyto PF07565.8 CDI75232.1 - 1.1 8.7 10.9 1.2 8.5 7.5 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain TMEM51 PF15345.1 CDI75232.1 - 1.3 8.6 17.0 1.8 8.1 11.8 1.2 1 0 0 1 1 1 0 Transmembrane protein 51 Ycf1 PF05758.7 CDI75232.1 - 3.1 5.3 13.3 3.9 5.0 9.2 1.0 1 0 0 1 1 1 0 Ycf1 eIF-3_zeta PF05091.7 CDI75232.1 - 3.2 6.2 15.6 4 5.9 10.8 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF4647 PF15504.1 CDI75232.1 - 3.2 6.5 16.8 3.6 6.3 11.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4647) Herpes_env PF01673.13 CDI75232.1 - 4.3 5.7 13.3 5 5.5 9.2 1.0 1 0 0 1 1 1 0 Herpesvirus putative major envelope glycoprotein SpoVR PF04293.8 CDI75232.1 - 5 5.3 12.2 7 4.9 8.5 1.3 1 0 0 1 1 1 0 SpoVR like protein ThylakoidFormat PF11264.3 CDI75232.1 - 5.7 6.4 17.9 0.58 9.7 9.6 1.4 2 0 0 2 2 2 0 Thylakoid formation protein Hid1 PF12722.2 CDI75232.1 - 6.7 4.2 11.8 7.2 4.1 8.2 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Ndc1_Nup PF09531.5 CDI75232.1 - 8.2 4.7 10.6 8.3 4.6 7.3 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Exonuc_VII_L PF02601.10 CDI75232.1 - 8.7 5.4 18.7 11 5.1 13.0 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Activator_LAG-3 PF11498.3 CDI75233.1 - 0.013 14.2 30.5 0.014 14.1 21.1 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 DUF445 PF04286.7 CDI75233.1 - 0.015 14.8 9.4 0.016 14.7 6.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF445) HI0933_like PF03486.9 CDI75233.1 - 0.21 10.0 10.9 0.23 9.8 7.6 1.2 1 0 0 1 1 1 0 HI0933-like protein FliL PF03748.9 CDI75233.1 - 0.57 10.2 13.5 0.029 14.3 3.0 2.1 1 1 1 2 2 2 0 Flagellar basal body-associated protein FliL Band_7_1 PF13421.1 CDI75233.1 - 0.95 8.9 4.9 1.2 8.6 3.4 1.2 1 0 0 1 1 1 0 SPFH domain-Band 7 family SOBP PF15279.1 CDI75233.1 - 2.6 8.3 9.3 2.8 8.2 6.5 1.0 1 0 0 1 1 1 0 Sine oculis-binding protein Med15 PF09606.5 CDI75233.1 - 3.3 5.8 41.5 3.6 5.6 28.8 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Chlam_vir PF05475.6 CDI75233.1 - 3.8 6.5 8.1 1.8 7.5 2.8 1.9 1 1 1 2 2 2 0 Chlamydia virulence protein PGP3-D Trigger_N PF05697.8 CDI75233.1 - 6.7 6.5 7.4 5.6 6.7 0.9 2.2 1 1 1 2 2 2 0 Bacterial trigger factor protein (TF) RE_TdeIII PF09520.5 CDI75234.1 - 0.027 13.7 2.5 0.033 13.4 1.7 1.3 1 0 0 1 1 1 0 Type II restriction endonuclease, TdeIII Pol_alpha_B_N PF08418.5 CDI75234.1 - 0.034 13.7 10.3 0.048 13.1 7.1 1.2 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal DUF445 PF04286.7 CDI75234.1 - 0.061 12.8 5.6 0.061 12.8 3.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF445) DUF330 PF03886.8 CDI75234.1 - 0.066 12.5 26.0 0.0098 15.2 9.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF330) Salt_tol_Pase PF09506.5 CDI75234.1 - 0.096 11.2 3.7 0.1 11.1 2.5 1.1 1 0 0 1 1 1 0 Glucosylglycerol-phosphate phosphatase (Salt_tol_Pase) OTU PF02338.14 CDI75234.1 - 0.16 12.5 1.6 0.17 12.4 1.1 1.3 1 0 0 1 1 1 0 OTU-like cysteine protease DUF668 PF05003.7 CDI75234.1 - 0.18 12.0 5.4 0.35 11.1 3.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF668) DUF1690 PF07956.6 CDI75234.1 - 0.2 11.6 11.8 0.23 11.4 8.2 1.1 1 0 0 1 1 1 0 Protein of Unknown function (DUF1690) CsoSCA PF08936.5 CDI75234.1 - 0.29 9.4 10.2 0.32 9.2 7.1 1.1 1 0 0 1 1 1 0 Carboxysome Shell Carbonic Anhydrase YpjP PF14005.1 CDI75234.1 - 0.31 10.8 2.5 0.43 10.3 1.7 1.3 1 0 0 1 1 1 0 YpjP-like protein FragX_IP PF05994.6 CDI75234.1 - 0.35 8.6 8.2 0.41 8.3 5.7 1.0 1 0 0 1 1 1 0 Cytoplasmic Fragile-X interacting family Ofd1_CTDD PF10637.4 CDI75234.1 - 0.57 9.2 7.0 0.6 9.1 4.9 1.1 1 0 0 1 1 1 0 Oxoglutarate and iron-dependent oxygenase degradation C-term Mmp37 PF09139.6 CDI75234.1 - 0.81 8.6 8.5 0.85 8.5 5.9 1.1 1 0 0 1 1 1 0 Mitochondrial matrix Mmp37 MCPVI PF02993.9 CDI75234.1 - 1.3 9.1 12.5 1.7 8.7 8.7 1.1 1 0 0 1 1 1 0 Minor capsid protein VI DUF3533 PF12051.3 CDI75234.1 - 1.3 7.6 15.5 0.97 8.1 9.9 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3533) LCD1 PF09798.4 CDI75234.1 - 1.5 6.6 15.2 1.8 6.4 10.5 1.0 1 0 0 1 1 1 0 DNA damage checkpoint protein DUF3589 PF12141.3 CDI75234.1 - 1.6 6.8 7.5 1.9 6.6 5.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3589) DUF2294 PF10057.4 CDI75234.1 - 2 8.0 8.3 3.7 7.2 5.8 1.5 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2294) PAT1 PF09770.4 CDI75234.1 - 2.2 6.4 23.1 2.1 6.4 16.0 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 HI0933_like PF03486.9 CDI75234.1 - 5.9 5.2 15.0 4.3 5.7 9.8 1.3 1 1 0 1 1 1 0 HI0933-like protein Vps39_2 PF10367.4 CDI75234.1 - 6.5 6.9 11.9 10 6.3 8.2 1.3 1 1 0 1 1 1 0 Vacuolar sorting protein 39 domain 2 2OG-FeII_Oxy_2 PF13532.1 CDI75234.1 - 7.7 6.2 7.5 8.2 6.2 5.2 1.1 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Med15 PF09606.5 CDI75235.1 - 0.00064 18.0 87.7 0.00067 18.0 60.8 1.0 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal CD20 PF04103.10 CDI75235.1 - 0.0038 17.1 0.1 0.0038 17.1 0.0 2.5 2 1 1 3 3 3 1 CD20-like family TauE PF01925.14 CDI75235.1 - 0.069 12.5 0.9 0.09 12.2 0.6 1.1 1 0 0 1 1 1 0 Sulfite exporter TauE/SafE PAT1 PF09770.4 CDI75235.1 - 0.12 10.5 75.4 0.14 10.3 52.2 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Ycf1 PF05758.7 CDI75235.1 - 0.2 9.3 22.7 0.18 9.4 15.7 1.2 1 0 0 1 1 1 0 Ycf1 GAGA_bind PF06217.7 CDI75235.1 - 2.8 7.8 33.9 3.3 7.5 23.5 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family DUF588 PF04535.7 CDI75235.1 - 3.4 7.2 8.0 6.4 6.3 5.5 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF588) CAF-1_p150 PF11600.3 CDI75235.1 - 7.6 5.8 54.0 19 4.5 37.4 1.6 1 1 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Ribosomal_60s PF00428.14 CDI75236.1 - 2.1 8.7 13.8 7.6 7.0 9.5 1.9 1 0 0 1 1 1 0 60s Acidic ribosomal protein SSP160 PF06933.6 CDI75237.1 - 0.00086 17.4 28.1 0.00095 17.2 19.4 1.0 1 0 0 1 1 1 1 Special lobe-specific silk protein SSP160 Pex14_N PF04695.8 CDI75237.1 - 0.046 13.7 5.1 0.058 13.4 3.5 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Plasmodium_Vir PF05795.6 CDI75237.1 - 0.3 10.2 5.0 0.36 9.9 3.4 1.0 1 0 0 1 1 1 0 Plasmodium vivax Vir protein DUF566 PF04484.7 CDI75237.1 - 1.8 7.9 19.7 2.1 7.7 13.7 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF566) DUF4602 PF15375.1 CDI75237.1 - 2 8.4 8.1 5.6 7.0 5.6 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4602) Apc1 PF12859.2 CDI75237.1 - 3.2 8.0 9.4 4.5 7.5 6.5 1.2 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 1 Macoilin PF09726.4 CDI75237.1 - 4.1 5.5 21.0 4.9 5.3 14.6 1.0 1 0 0 1 1 1 0 Transmembrane protein PAP1 PF08601.5 CDI75237.1 - 4.4 6.8 17.1 5.3 6.6 11.9 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 Presenilin PF01080.12 CDI75237.1 - 4.9 5.8 8.5 5.1 5.8 5.9 1.1 1 0 0 1 1 1 0 Presenilin Sec3_C PF09763.4 CDI75237.1 - 5.3 5.0 12.3 6.5 4.7 8.5 1.0 1 0 0 1 1 1 0 Exocyst complex component Sec3 NPR3 PF03666.8 CDI75237.1 - 7.1 5.0 8.2 8.7 4.7 5.7 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Pox_A12 PF04651.8 CDI75237.1 - 7.9 6.5 15.2 11 6.1 10.5 1.2 1 0 0 1 1 1 0 Poxvirus A12 protein DUF605 PF04652.11 CDI75238.1 - 0.00043 19.7 31.9 0.00043 19.7 22.1 6.1 4 2 1 5 5 5 1 Vta1 like PAT1 PF09770.4 CDI75238.1 - 0.0022 16.3 41.0 0.0022 16.3 28.4 5.3 4 1 0 5 5 5 2 Topoisomerase II-associated protein PAT1 Ribosomal_60s PF00428.14 CDI75239.1 - 0.078 13.3 15.0 0.16 12.4 3.2 2.2 2 0 0 2 2 2 0 60s Acidic ribosomal protein Mit_ribos_Mrp51 PF11709.3 CDI75239.1 - 0.089 12.0 0.6 0.11 11.7 0.4 1.0 1 0 0 1 1 1 0 Mitochondrial ribosomal protein subunit DRY_EERY PF09750.4 CDI75239.1 - 0.091 12.8 2.2 0.58 10.2 0.0 2.1 2 0 0 2 2 2 0 Alternative splicing regulator Chorion_2 PF03964.10 CDI75239.1 - 0.28 11.7 10.1 1.1 9.8 0.9 2.2 2 0 0 2 2 2 0 Chorion family 2 Herpes_capsid PF06112.6 CDI75239.1 - 1.3 9.0 6.7 1.7 8.6 4.7 1.1 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein DUF966 PF06136.8 CDI75239.1 - 1.6 8.0 5.7 1.8 7.8 4.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Prenyltrans PF00432.16 CDI75239.1 - 3.5 7.2 6.6 0.19 11.3 0.6 1.9 2 0 0 2 2 2 0 Prenyltransferase and squalene oxidase repeat Ldh_1_C PF02866.13 CDI75239.1 - 4 7.1 7.3 5 6.8 4.2 1.6 1 1 1 2 2 2 0 lactate/malate dehydrogenase, alpha/beta C-terminal domain Hist_deacetyl PF00850.14 CDI75239.1 - 5.1 6.2 8.3 34 3.5 5.8 1.9 1 1 0 1 1 1 0 Histone deacetylase domain LMBR1 PF04791.11 CDI75240.1 - 0.78 8.2 7.9 1.8 7.0 5.5 1.6 1 1 0 1 1 1 0 LMBR1-like membrane protein CAF-1_p150 PF11600.3 CDI75240.1 - 6 6.1 41.1 0.22 10.8 7.0 2.4 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal NST1 PF13945.1 CDI75241.1 - 0.0099 15.9 2.6 0.011 15.7 1.8 1.2 1 0 0 1 1 1 1 Salt tolerance down-regulator TraW_N PF12477.3 CDI75241.1 - 0.051 13.5 2.9 0.051 13.5 2.0 3.2 3 0 0 3 3 3 0 Sex factor F TraW protein N terminal DUF3807 PF12720.2 CDI75241.1 - 0.24 11.5 3.6 0.3 11.2 2.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) DUF2890 PF11081.3 CDI75241.1 - 1.1 9.3 5.5 1.5 8.8 3.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) Nop53 PF07767.6 CDI75241.1 - 1.4 7.8 7.1 1.5 7.7 4.9 1.0 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Rox3 PF08633.5 CDI75241.1 - 2.6 8.3 6.2 3.9 7.7 4.3 1.5 1 1 0 1 1 1 0 Rox3 mediator complex subunit DUF1682 PF07946.9 CDI75241.1 - 4 6.2 5.5 5 5.8 3.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Prenyltrans_2 PF13249.1 CDI75241.1 - 4.3 7.7 11.3 6.9 7.1 7.9 1.4 1 1 0 1 1 1 0 Prenyltransferase-like Med3 PF11593.3 CDI75242.1 - 0.00018 20.9 46.5 0.00018 20.9 32.2 19.6 10 6 6 16 16 16 1 Mediator complex subunit 3 fungal OmpH PF03938.9 CDI75242.1 - 0.0049 16.8 29.3 0.0049 16.8 20.3 10.6 4 2 2 6 6 6 1 Outer membrane protein (OmpH-like) Ribosomal_60s PF00428.14 CDI75243.1 - 0.00037 20.8 17.3 0.00037 20.8 12.0 5.5 4 1 0 4 4 4 1 60s Acidic ribosomal protein UBA_e1_thiolCys PF10585.4 CDI75245.1 - 8.2e-13 47.5 0.7 2.3e-12 46.0 0.5 1.8 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site DUF1510 PF07423.6 CDI75245.1 - 7.3e-06 25.5 11.5 7.3e-06 25.5 8.0 3.5 2 1 1 3 3 3 1 Protein of unknown function (DUF1510) IncA PF04156.9 CDI75245.1 - 0.00016 21.3 16.7 0.00016 21.3 11.6 3.7 2 1 1 3 3 3 1 IncA protein Utp14 PF04615.8 CDI75245.1 - 0.00027 19.2 9.8 0.00027 19.2 6.8 3.0 2 1 1 3 3 3 1 Utp14 protein Raftlin PF15250.1 CDI75245.1 - 0.0033 16.0 8.8 0.0033 16.0 6.1 3.1 2 1 1 3 3 3 1 Raftlin ApbA PF02558.11 CDI75245.1 - 0.0044 16.4 0.4 0.017 14.5 0.3 2.0 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ThiF PF00899.16 CDI75245.1 - 0.015 15.1 0.6 0.042 13.6 0.4 1.7 1 0 0 1 1 1 0 ThiF family TPP_enzyme_C PF02775.16 CDI75245.1 - 0.75 9.3 14.5 0.072 12.6 3.1 3.3 2 2 1 3 3 3 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Thionin PF00321.12 CDI75245.1 - 3.3 8.0 8.3 0.094 12.9 0.9 2.1 2 0 0 2 2 2 0 Plant thionin eIF3_subunit PF08597.5 CDI75246.1 - 4.1 6.9 11.9 6.1 6.3 8.3 1.2 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit YlqD PF11068.3 CDI75246.1 - 7.7 6.5 15.6 11 6.0 10.8 1.1 1 0 0 1 1 1 0 YlqD protein NAM-associated PF14303.1 CDI75247.1 - 0.0097 16.2 8.1 0.0097 16.2 5.6 8.5 6 3 1 8 8 8 1 No apical meristem-associated C-terminal domain LMBR1 PF04791.11 CDI75248.1 - 4.9e-05 22.1 0.0 0.0029 16.2 0.0 2.1 1 1 0 2 2 2 1 LMBR1-like membrane protein Ribosomal_60s PF00428.14 CDI75248.1 - 0.00012 22.3 34.1 0.03 14.6 6.3 3.8 3 0 0 3 3 3 2 60s Acidic ribosomal protein DUF3617 PF12276.3 CDI75248.1 - 0.00077 18.9 1.5 0.00077 18.9 1.0 4.6 4 1 0 4 4 4 1 Protein of unknown function (DUF3617) 60KD_IMP PF02096.15 CDI75248.1 - 0.057 13.0 0.0 0.057 13.0 0.0 3.9 3 1 0 3 3 3 0 60Kd inner membrane protein DUF457 PF04307.9 CDI75248.1 - 0.088 12.1 0.0 0.3 10.4 0.0 1.9 2 1 0 2 2 2 0 Predicted membrane-bound metal-dependent hydrolase (DUF457) OppC_N PF12911.2 CDI75248.1 - 0.1 11.9 0.2 0.39 10.1 0.1 2.0 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C EphA2_TM PF14575.1 CDI75248.1 - 0.65 10.4 0.0 0.65 10.4 0.0 4.8 3 2 1 4 4 4 0 Ephrin type-A receptor 2 transmembrane domain MASE1 PF05231.9 CDI75248.1 - 4.6 6.1 9.9 0.58 9.1 0.1 2.7 2 1 1 3 3 3 0 MASE1 GAGA_bind PF06217.7 CDI75248.1 - 5.4 6.8 30.7 0.76 9.6 7.0 2.3 2 0 0 2 2 2 0 GAGA binding protein-like family Hid1 PF12722.2 CDI75248.1 - 9.1 3.8 33.6 1.4 6.5 8.1 2.2 2 0 0 2 2 2 0 High-temperature-induced dauer-formation protein UPF0564 PF10595.4 CDI75249.1 - 0.0074 15.2 32.7 0.061 12.2 16.4 2.3 2 0 0 2 2 2 2 Uncharacterised protein family UPF0564 AAA_23 PF13476.1 CDI75249.1 - 0.046 14.0 0.4 0.046 14.0 0.3 2.7 3 0 0 3 3 3 0 AAA domain CAF-1_p150 PF11600.3 CDI75250.1 - 0.0005 19.5 115.8 0.039 13.3 41.1 2.4 2 0 0 2 2 2 2 Chromatin assembly factor 1 complex p150 subunit, N-terminal CDC27 PF09507.5 CDI75250.1 - 3.2 6.8 110.1 0.076 12.2 41.2 2.0 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 AA_permease_2 PF13520.1 CDI75251.1 - 0.00012 20.7 0.2 0.00058 18.5 0.4 1.8 2 0 0 2 2 2 1 Amino acid permease TMEM154 PF15102.1 CDI75251.1 - 0.00052 19.7 3.3 0.00052 19.7 2.3 9.1 5 2 2 8 8 8 1 TMEM154 protein family DUF4064 PF13273.1 CDI75251.1 - 0.012 15.7 0.5 0.012 15.7 0.4 5.1 5 2 0 5 5 5 0 Protein of unknown function (DUF4064) EphA2_TM PF14575.1 CDI75251.1 - 0.019 15.3 1.4 0.019 15.3 1.0 8.4 5 3 3 8 8 8 0 Ephrin type-A receptor 2 transmembrane domain CD20 PF04103.10 CDI75251.1 - 0.039 13.8 0.1 0.039 13.8 0.1 6.1 3 2 2 5 5 5 0 CD20-like family DUF843 PF05814.6 CDI75251.1 - 0.048 13.4 1.4 4.9 7.0 0.0 3.2 2 1 1 3 3 3 0 Baculovirus protein of unknown function (DUF843) GPI2 PF06432.6 CDI75251.1 - 0.32 10.3 4.4 8.7 5.6 0.0 3.2 4 0 0 4 4 4 0 Phosphatidylinositol N-acetylglucosaminyltransferase Frag1 PF10277.4 CDI75251.1 - 0.32 10.4 1.2 1.1 8.6 0.2 2.0 2 0 0 2 2 2 0 Frag1/DRAM/Sfk1 family PBP1_TM PF14812.1 CDI75251.1 - 3.9 7.8 26.9 24 5.3 0.9 5.6 4 0 0 4 4 4 0 Transmembrane domain of transglycosylase PBP1 at N-terminal SUR7 PF06687.7 CDI75251.1 - 7.1 6.1 7.0 1.3 8.5 1.4 2.1 1 1 1 2 2 2 0 SUR7/PalI family WD40 PF00400.27 CDI75252.1 - 3.6e-20 71.0 17.0 6.9e-07 28.9 0.1 6.3 6 0 0 6 6 6 4 WD domain, G-beta repeat Nucleoporin_N PF08801.6 CDI75252.1 - 0.51 9.0 6.4 1.6 7.4 4.5 1.7 1 1 1 2 2 2 0 Nup133 N terminal like SPX PF03105.14 CDI75253.1 - 0.0098 15.6 0.5 0.0098 15.6 0.4 2.1 2 0 0 2 2 2 1 SPX domain Secretin_N_2 PF07655.8 CDI75253.1 - 0.029 14.7 8.4 0.029 14.7 5.8 2.6 3 0 0 3 3 3 0 Secretin N-terminal domain Corona_nucleoca PF00937.13 CDI75253.1 - 10 4.9 29.2 0.22 10.4 2.2 3.1 3 0 0 3 3 3 0 Coronavirus nucleocapsid protein PCEMA1 PF07418.6 CDI75255.1 - 5.2 6.3 9.9 6.9 5.9 6.9 1.1 1 0 0 1 1 1 0 Acidic phosphoprotein precursor PCEMA1 DUF4512 PF14975.1 CDI75255.1 - 9.4 7.1 11.1 1.2 10.0 3.1 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4512) PIH1 PF08190.7 CDI75257.1 - 1.9e-15 57.1 0.0 8.3e-13 48.4 0.0 2.3 1 1 1 2 2 2 2 pre-RNA processing PIH1/Nop17 FLO_LFY PF01698.11 CDI75258.1 - 0.0018 17.2 4.8 0.0021 17.0 3.4 1.1 1 0 0 1 1 1 1 Floricaula / Leafy protein NMDAR2_C PF10565.4 CDI75258.1 - 0.0035 16.1 14.9 0.0039 15.9 10.3 1.0 1 0 0 1 1 1 1 N-methyl D-aspartate receptor 2B3 C-terminus SAGA-Tad1 PF12767.2 CDI75258.1 - 0.0045 16.6 10.3 0.0049 16.5 7.1 1.1 1 0 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit PsaN PF05479.6 CDI75258.1 - 0.0061 16.5 6.9 0.46 10.4 0.5 2.1 2 0 0 2 2 2 2 Photosystem I reaction centre subunit N (PSAN or PSI-N) Med15 PF09606.5 CDI75258.1 - 0.017 13.3 33.5 0.019 13.2 23.3 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal HemX PF04375.9 CDI75258.1 - 0.038 12.5 23.5 0.05 12.1 16.3 1.2 1 0 0 1 1 1 0 HemX PA26 PF04636.8 CDI75258.1 - 0.054 12.1 6.8 0.059 12.0 4.7 1.0 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) DUF4045 PF13254.1 CDI75258.1 - 0.057 12.7 9.6 0.063 12.5 6.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Ycf1 PF05758.7 CDI75258.1 - 0.067 10.9 11.9 0.072 10.8 8.2 1.0 1 0 0 1 1 1 0 Ycf1 PAT1 PF09770.4 CDI75258.1 - 0.079 11.1 30.5 0.089 11.0 21.2 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Zip PF02535.17 CDI75258.1 - 0.17 10.8 2.5 0.2 10.6 1.7 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter TFIIA PF03153.8 CDI75258.1 - 0.17 11.7 20.6 0.18 11.6 14.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Cellulose_synt PF03552.9 CDI75258.1 - 0.19 9.9 1.6 0.2 9.8 1.1 1.1 1 0 0 1 1 1 0 Cellulose synthase TMEM51 PF15345.1 CDI75258.1 - 0.2 11.3 12.6 0.27 10.8 8.7 1.2 1 0 0 1 1 1 0 Transmembrane protein 51 Dicty_REP PF05086.7 CDI75258.1 - 0.27 8.9 5.8 0.3 8.7 4.0 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein YjgP_YjgQ PF03739.9 CDI75258.1 - 0.28 9.9 2.8 0.34 9.6 1.9 1.1 1 0 0 1 1 1 0 Predicted permease YjgP/YjgQ family DUF2201_N PF13203.1 CDI75258.1 - 0.33 10.0 15.4 0.41 9.7 10.6 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain DUF4192 PF13830.1 CDI75258.1 - 0.4 10.2 13.8 0.58 9.7 9.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4192) AUX_IAA PF02309.11 CDI75258.1 - 0.44 10.2 7.9 0.52 10.0 5.5 1.2 1 0 0 1 1 1 0 AUX/IAA family CDC45 PF02724.9 CDI75258.1 - 0.45 8.5 11.7 0.51 8.2 8.1 1.0 1 0 0 1 1 1 0 CDC45-like protein DUF2076 PF09849.4 CDI75258.1 - 0.45 10.5 24.3 0.6 10.1 4.2 2.0 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2076) FAM60A PF15396.1 CDI75258.1 - 0.53 9.9 10.2 0.65 9.7 7.1 1.1 1 0 0 1 1 1 0 Protein Family FAM60A RR_TM4-6 PF06459.7 CDI75258.1 - 0.58 10.0 13.5 0.68 9.7 9.4 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Hid1 PF12722.2 CDI75258.1 - 0.59 7.7 13.0 0.65 7.5 9.0 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF1754 PF08555.5 CDI75258.1 - 0.6 10.7 15.6 0.87 10.2 10.8 1.2 1 0 0 1 1 1 0 Eukaryotic family of unknown function (DUF1754) eIF-3_zeta PF05091.7 CDI75258.1 - 0.7 8.4 14.6 0.82 8.2 10.1 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF4578 PF15147.1 CDI75258.1 - 0.81 10.0 15.3 1.2 9.5 10.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4578) Rtf2 PF04641.7 CDI75258.1 - 0.9 8.6 14.3 1.2 8.3 9.9 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger Gag_spuma PF03276.9 CDI75258.1 - 0.98 7.6 25.5 1.3 7.2 17.7 1.1 1 0 0 1 1 1 0 Spumavirus gag protein Hist_deacetyl PF00850.14 CDI75258.1 - 1 8.5 5.4 1.3 8.1 3.8 1.1 1 0 0 1 1 1 0 Histone deacetylase domain Suf PF05843.9 CDI75258.1 - 1.1 8.9 15.4 1.5 8.4 10.7 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF4175 PF13779.1 CDI75258.1 - 1.3 6.6 35.0 1.5 6.3 24.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) SpoVR PF04293.8 CDI75258.1 - 1.4 7.2 15.9 1.8 6.8 11.0 1.1 1 0 0 1 1 1 0 SpoVR like protein Paramyxo_ncap PF00973.14 CDI75258.1 - 1.7 7.2 8.4 1.9 7.1 5.8 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein DDHD PF02862.12 CDI75258.1 - 1.8 8.3 12.2 2.2 8.0 8.5 1.1 1 0 0 1 1 1 0 DDHD domain SprA-related PF12118.3 CDI75258.1 - 1.8 7.7 31.3 3.5 6.8 21.7 1.5 1 0 0 1 1 1 0 SprA-related family LMBR1 PF04791.11 CDI75258.1 - 2.1 6.8 6.4 2.4 6.6 4.4 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein NARP1 PF12569.3 CDI75258.1 - 2.2 6.9 15.9 2.6 6.7 11.0 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 SelP_N PF04592.9 CDI75258.1 - 2.3 7.5 13.5 3.2 7.0 9.4 1.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region RNA_pol_Rpb1_5 PF04998.12 CDI75258.1 - 3.4 6.8 7.6 4.2 6.5 5.2 1.1 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 Spore_coat_CotO PF14153.1 CDI75258.1 - 4 6.8 23.5 4.8 6.5 16.3 1.1 1 0 0 1 1 1 0 Spore coat protein CotO Bud13 PF09736.4 CDI75258.1 - 4.2 7.6 26.0 5.8 7.1 18.0 1.1 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex DUF3464 PF11947.3 CDI75258.1 - 5 6.5 13.3 7.2 6.0 9.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) F-protein PF00469.15 CDI75258.1 - 5.2 6.3 11.5 7 5.9 8.0 1.1 1 0 0 1 1 1 0 Negative factor, (F-Protein) or Nef Gti1_Pac2 PF09729.4 CDI75258.1 - 5.7 6.7 10.2 8 6.2 7.1 1.2 1 0 0 1 1 1 0 Gti1/Pac2 family DHHW PF14286.1 CDI75258.1 - 6 6.0 9.1 7 5.8 6.3 1.1 1 0 0 1 1 1 0 DHHW protein Peptidase_S64 PF08192.6 CDI75258.1 - 6 5.0 9.9 7.3 4.7 6.8 1.0 1 0 0 1 1 1 0 Peptidase family S64 DOR PF14839.1 CDI75258.1 - 6.2 6.5 21.7 8.1 6.1 15.0 1.3 1 0 0 1 1 1 0 DOR family Neur_chan_memb PF02932.11 CDI75258.1 - 7.7 6.3 9.7 9.6 6.0 6.7 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Band_3_cyto PF07565.8 CDI75258.1 - 8.3 5.8 13.7 12 5.3 9.5 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Presenilin PF01080.12 CDI75258.1 - 8.7 5.0 7.9 10 4.8 5.5 1.1 1 0 0 1 1 1 0 Presenilin Radical_SAM_N PF08497.5 CDI75258.1 - 9.1 5.1 8.1 12 4.7 5.6 1.1 1 0 0 1 1 1 0 Radical SAM N-terminal CEP170_C PF15308.1 CDI75259.1 - 0.52 8.4 6.7 0.55 8.4 4.6 1.0 1 0 0 1 1 1 0 CEP170 C-terminus Collagen PF01391.13 CDI75260.1 - 0.00034 20.1 4.5 0.00034 20.1 3.1 2.3 2 0 0 2 2 2 1 Collagen triple helix repeat (20 copies) CDC45 PF02724.9 CDI75261.1 - 6.8 4.5 42.6 7.5 4.4 29.5 1.1 1 0 0 1 1 1 0 CDC45-like protein FAM60A PF15396.1 CDI75262.1 - 0.76 9.4 30.2 1.4 8.5 7.1 2.2 2 0 0 2 2 2 0 Protein Family FAM60A Zip PF02535.17 CDI75262.1 - 2.1 7.2 12.9 0.78 8.6 0.6 2.2 2 0 0 2 2 2 0 ZIP Zinc transporter DUF1510 PF07423.6 CDI75262.1 - 2.5 7.4 39.2 3.5 6.9 9.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) DUF258 PF03193.11 CDI75264.1 - 5.1e-05 22.5 0.0 6.9e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 CDI75264.1 - 0.00038 20.4 2.3 0.00047 20.1 0.1 1.9 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 CDI75264.1 - 0.0083 16.2 0.1 0.016 15.3 0.0 1.5 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 CDI75264.1 - 0.0099 16.6 0.0 0.016 16.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.10 CDI75264.1 - 0.016 13.9 0.0 0.02 13.5 0.0 1.0 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein NACHT PF05729.7 CDI75264.1 - 0.017 14.7 0.2 0.026 14.1 0.1 1.3 1 0 0 1 1 1 0 NACHT domain Zeta_toxin PF06414.7 CDI75264.1 - 0.039 13.0 0.4 0.061 12.4 0.2 1.4 1 1 0 1 1 1 0 Zeta toxin AAA_18 PF13238.1 CDI75264.1 - 0.065 13.5 0.2 0.1 12.9 0.2 1.2 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 CDI75264.1 - 0.073 13.3 0.0 0.13 12.6 0.0 1.3 1 0 0 1 1 1 0 ABC transporter AAA_30 PF13604.1 CDI75264.1 - 0.079 12.5 0.4 0.079 12.5 0.2 2.2 1 1 1 2 2 1 0 AAA domain Guanylate_kin PF00625.16 CDI75264.1 - 0.17 11.3 0.0 0.25 10.7 0.0 1.3 1 0 0 1 1 1 0 Guanylate kinase AAA_29 PF13555.1 CDI75264.1 - 0.23 11.0 0.0 0.23 11.0 0.0 1.8 2 0 0 2 2 1 0 P-loop containing region of AAA domain AAA_33 PF13671.1 CDI75264.1 - 0.27 11.1 2.4 0.45 10.3 0.1 2.0 2 0 0 2 2 2 0 AAA domain Pribosyltran PF00156.22 CDI75266.1 - 7.3 6.3 12.1 5.6 6.6 0.1 4.4 4 0 0 4 4 4 0 Phosphoribosyl transferase domain DUF2029 PF09594.5 CDI75267.1 - 0.41 10.1 12.2 1.7 8.0 0.6 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2029) Peptidase_U4 PF03419.8 CDI75267.1 - 2.4 7.1 2.2 22 4.0 1.5 2.8 1 0 0 1 1 1 0 Sporulation factor SpoIIGA Caldesmon PF02029.10 CDI75268.1 - 0.00026 19.5 20.8 0.00026 19.5 14.4 4.1 3 1 1 4 4 4 2 Caldesmon Pox_Ag35 PF03286.9 CDI75268.1 - 0.0016 17.9 13.5 0.0016 17.9 9.4 4.6 6 0 0 6 6 6 2 Pox virus Ag35 surface protein IncA PF04156.9 CDI75268.1 - 0.0039 16.8 4.9 0.0039 16.8 3.4 6.7 5 2 1 6 6 6 1 IncA protein Ribosomal_60s PF00428.14 CDI75268.1 - 0.0095 16.3 8.9 0.0095 16.3 6.2 15.6 8 5 2 11 11 11 3 60s Acidic ribosomal protein SR-25 PF10500.4 CDI75269.1 - 0.0012 18.3 21.1 0.0013 18.2 14.6 1.0 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein PBP1_TM PF14812.1 CDI75269.1 - 0.55 10.5 8.9 0.7 10.2 6.2 1.2 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Gti1_Pac2 PF09729.4 CDI75269.1 - 0.56 10.0 15.2 0.62 9.9 10.5 1.1 1 0 0 1 1 1 0 Gti1/Pac2 family Spc7_N PF15402.1 CDI75269.1 - 1.1 7.1 25.7 1.3 6.9 17.8 1.0 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 DUF4175 PF13779.1 CDI75269.1 - 2.1 5.9 42.3 2.5 5.6 29.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) FYDLN_acid PF09538.5 CDI75269.1 - 2.8 8.5 8.5 3.2 8.3 5.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) SelP_N PF04592.9 CDI75269.1 - 3.6 6.8 18.9 3.9 6.7 13.1 1.0 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Dsh_C PF12316.3 CDI75269.1 - 3.7 7.6 17.0 4.2 7.4 11.8 1.0 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal FimP PF09766.4 CDI75269.1 - 3.9 6.4 29.9 4.4 6.2 20.7 1.1 1 0 0 1 1 1 0 Fms-interacting protein BRF1 PF07741.8 CDI75269.1 - 4.3 7.6 18.9 5 7.4 13.1 1.2 1 0 0 1 1 1 0 Brf1-like TBP-binding domain DUF3306 PF11748.3 CDI75269.1 - 4.4 7.9 14.6 4.8 7.8 10.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3306) DUF1764 PF08576.5 CDI75269.1 - 4.6 8.0 22.6 5.4 7.8 15.6 1.1 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) SprA-related PF12118.3 CDI75269.1 - 4.9 6.4 39.6 4.9 6.3 27.5 1.0 1 0 0 1 1 1 0 SprA-related family Bud13 PF09736.4 CDI75269.1 - 5.7 7.1 24.4 6.2 7.0 16.9 1.1 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex Pal1 PF08316.6 CDI75269.1 - 5.8 7.3 14.6 6.3 7.2 10.1 1.0 1 0 0 1 1 1 0 Pal1 cell morphology protein NARP1 PF12569.3 CDI75269.1 - 6 5.5 19.8 5.5 5.6 13.7 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DDRGK PF09756.4 CDI75269.1 - 6.2 6.1 24.9 6.6 6.0 17.2 1.0 1 0 0 1 1 1 0 DDRGK domain Peptidase_S49_N PF08496.5 CDI75269.1 - 7.3 6.3 17.0 8 6.2 11.8 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal RR_TM4-6 PF06459.7 CDI75269.1 - 7.3 6.3 18.6 7.6 6.3 12.9 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF4407 PF14362.1 CDI75269.1 - 7.6 5.3 20.4 8.2 5.2 14.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF853 PF05872.7 CDI75269.1 - 8.1 4.6 15.4 8.5 4.5 10.7 1.0 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) YqfQ PF14181.1 CDI75269.1 - 9.3 6.2 23.9 9.9 6.1 16.6 1.1 1 0 0 1 1 1 0 YqfQ-like protein Kinase-like PF14531.1 CDI75270.1 - 0.00086 18.3 0.0 0.0023 16.9 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Pkinase PF00069.20 CDI75270.1 - 0.037 13.1 0.0 0.055 12.6 0.0 1.3 1 0 0 1 1 1 0 Protein kinase domain Pkinase PF00069.20 CDI75271.1 - 1.8e-12 46.9 0.0 3.7e-11 42.6 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Kinase-like PF14531.1 CDI75271.1 - 2.8e-08 33.0 0.0 4.5e-08 32.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_Tyr PF07714.12 CDI75271.1 - 1.9e-06 27.1 0.0 5.3e-06 25.6 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Solute_trans_a PF03619.11 CDI75272.1 - 2.8e-09 36.7 0.0 0.0002 20.7 0.0 2.5 3 0 0 3 3 3 2 Organic solute transporter Ostalpha Pro_isomerase PF00160.16 CDI75274.1 - 3.3e-25 89.0 0.0 1.7e-22 80.2 0.0 2.1 1 1 1 2 2 2 2 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Kinase-like PF14531.1 CDI75275.1 - 0.00017 20.6 0.0 0.00029 19.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_Tyr PF07714.12 CDI75275.1 - 0.00038 19.6 0.0 0.00058 19.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 CDI75275.1 - 0.003 16.7 0.0 0.0044 16.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain DUF3186 PF11382.3 CDI75275.1 - 0.11 11.5 0.0 0.24 10.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3186) DnaJ PF00226.26 CDI75276.1 - 4.5e-33 112.7 4.7 4.1e-23 80.8 0.8 2.3 2 0 0 2 2 2 2 DnaJ domain Raftlin PF15250.1 CDI75276.1 - 0.024 13.2 0.0 0.029 12.9 0.0 1.2 1 0 0 1 1 1 0 Raftlin UPF0081 PF03652.10 CDI75277.1 - 1.3e-07 31.7 3.3 0.00022 21.3 0.0 3.8 3 1 0 3 3 3 2 Uncharacterised protein family (UPF0081) Med15 PF09606.5 CDI75277.1 - 0.77 7.8 71.6 0.071 11.3 31.6 2.2 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal RAB3GAP2_N PF14655.1 CDI75277.1 - 0.92 8.4 23.3 0.34 9.8 3.2 3.2 3 0 0 3 3 3 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Ribosomal_60s PF00428.14 CDI75277.1 - 1.1 9.7 53.1 0.055 13.8 2.3 4.7 4 0 0 4 4 4 0 60s Acidic ribosomal protein DUF2722 PF10846.3 CDI75277.1 - 3.7 6.4 28.5 1.2 8.0 1.1 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2722) Ndc1_Nup PF09531.5 CDI75277.1 - 9.6 4.4 15.2 18 3.6 0.0 2.1 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup DUF4131 PF13567.1 CDI75279.1 - 0.0019 17.6 0.1 0.0022 17.4 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4131) DUF3357 PF11837.3 CDI75279.1 - 0.024 14.4 1.6 0.44 10.4 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3357) DUF3506 PF12014.3 CDI75279.1 - 0.17 11.7 0.9 0.23 11.2 0.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3506) Ribosomal_L37 PF08561.5 CDI75279.1 - 0.28 10.7 2.3 0.41 10.2 1.6 1.4 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L37 DUF2489 PF10675.4 CDI75279.1 - 0.38 10.4 14.3 0.34 10.5 6.8 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2489) RAB3GAP2_N PF14655.1 CDI75279.1 - 0.93 8.4 5.6 1.1 8.1 3.9 1.2 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus p12I PF12233.3 CDI75279.1 - 0.95 9.7 6.1 1.2 9.4 4.2 1.2 1 0 0 1 1 1 0 Human adult T cell leukemia/lymphoma virus protein DUF4414 PF14377.1 CDI75279.1 - 1.8 8.5 12.0 2.3 8.1 8.3 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4414) Baculo_11_kDa PF06143.6 CDI75279.1 - 2 7.8 4.7 1.7 8.0 0.3 2.1 2 0 0 2 2 2 0 Baculovirus 11 kDa family YajC PF02699.10 CDI75279.1 - 2.5 7.8 10.3 2.2 8.0 1.8 2.3 2 0 0 2 2 2 0 Preprotein translocase subunit CAF-1_p150 PF11600.3 CDI75280.1 - 0.003 16.9 25.7 0.003 16.9 17.8 3.9 4 0 0 4 4 4 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal Neur_chan_memb PF02932.11 CDI75280.1 - 0.084 12.7 11.4 1.8 8.3 3.4 2.8 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region DUF1510 PF07423.6 CDI75280.1 - 2.4 7.4 22.9 1.5 8.1 10.3 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) Ycf1 PF05758.7 CDI75280.1 - 7.9 4.0 17.6 0.86 7.2 6.3 2.1 2 0 0 2 2 2 0 Ycf1 Herpes_UL87 PF03043.9 CDI75280.1 - 9.7 4.4 13.0 0.63 8.3 1.0 2.2 2 0 0 2 2 2 0 Herpesvirus UL87 family Pex14_N PF04695.8 CDI75281.1 - 0.017 15.1 3.7 0.017 15.1 2.6 2.2 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region POX PF07526.6 CDI75281.1 - 0.72 10.0 7.9 0.33 11.1 2.2 2.2 2 0 0 2 2 2 0 Associated with HOX VirE2 PF07229.7 CDI75281.1 - 3.5 5.9 5.7 4.7 5.5 3.9 1.1 1 0 0 1 1 1 0 VirE2 Pap_E4 PF02711.9 CDI75281.1 - 7 7.5 6.4 24 5.8 4.5 1.9 1 1 0 1 1 1 0 E4 protein Macoilin PF09726.4 CDI75281.1 - 9.4 4.3 16.4 14 3.8 11.4 1.3 1 0 0 1 1 1 0 Transmembrane protein DUF3395 PF11875.3 CDI75282.1 - 2.2e-21 76.0 0.0 3.1e-21 75.6 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3395) DUF1510 PF07423.6 CDI75283.1 - 1 8.6 39.3 1.1 8.6 27.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) PAT1 PF09770.4 CDI75284.1 - 1.8 6.6 102.2 1.6 6.8 29.4 2.3 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 DSPc PF00782.15 CDI75286.1 - 4.6e-06 26.2 0.2 4.6e-06 26.2 0.1 3.2 4 0 0 4 4 4 1 Dual specificity phosphatase, catalytic domain Spore_coat_CotO PF14153.1 CDI75286.1 - 0.00079 18.9 12.1 0.00079 18.9 8.4 7.6 6 2 1 7 7 7 4 Spore coat protein CotO Caldesmon PF02029.10 CDI75286.1 - 0.0023 16.4 18.9 0.0023 16.4 13.1 5.6 5 1 0 5 5 5 2 Caldesmon Hom_end_hint PF05203.11 CDI75286.1 - 0.0087 15.8 0.0 0.0087 15.8 0.0 6.4 7 0 0 7 7 7 1 Hom_end-associated Hint Zip PF02535.17 CDI75287.1 - 0.002 17.1 4.7 0.002 17.1 3.3 6.0 4 2 0 4 4 4 1 ZIP Zinc transporter Tim54 PF11711.3 CDI75287.1 - 0.0054 15.3 1.4 0.0054 15.3 0.9 6.5 5 3 1 6 6 6 1 Inner membrane protein import complex subunit Tim54 Pkinase PF00069.20 CDI75288.1 - 3.8e-12 45.9 0.0 3.8e-12 45.9 0.0 2.0 1 1 1 2 2 1 1 Protein kinase domain Spore_coat_CotO PF14153.1 CDI75288.1 - 0.0083 15.5 8.7 0.0085 15.5 6.1 1.1 1 0 0 1 1 1 1 Spore coat protein CotO Ctr PF04145.10 CDI75288.1 - 0.011 15.8 0.9 0.012 15.6 0.6 1.2 1 0 0 1 1 1 0 Ctr copper transporter family Folate_carrier PF01770.13 CDI75288.1 - 0.011 14.3 4.2 0.013 14.0 2.9 1.1 1 0 0 1 1 1 0 Reduced folate carrier Pex14_N PF04695.8 CDI75288.1 - 0.012 15.6 15.7 0.019 14.9 10.9 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region RskA PF10099.4 CDI75288.1 - 0.027 14.2 9.1 0.039 13.6 6.3 1.2 1 0 0 1 1 1 0 Anti-sigma-K factor rskA Nitroreductase PF00881.19 CDI75288.1 - 0.032 14.0 3.9 0.039 13.7 2.7 1.2 1 0 0 1 1 1 0 Nitroreductase family HSP90 PF00183.13 CDI75288.1 - 0.038 12.4 0.0 0.046 12.1 0.0 1.0 1 0 0 1 1 1 0 Hsp90 protein CD20 PF04103.10 CDI75288.1 - 0.047 13.6 0.8 0.078 12.9 0.5 1.4 1 0 0 1 1 1 0 CD20-like family Raftlin PF15250.1 CDI75288.1 - 0.084 11.3 8.5 0.093 11.2 5.9 1.0 1 0 0 1 1 1 0 Raftlin FimP PF09766.4 CDI75288.1 - 0.085 11.9 16.9 0.1 11.6 11.7 1.1 1 0 0 1 1 1 0 Fms-interacting protein Spt20 PF12090.3 CDI75288.1 - 0.2 10.9 10.9 0.27 10.5 7.6 1.3 1 0 0 1 1 1 0 Spt20 family Suf PF05843.9 CDI75288.1 - 0.22 11.2 16.5 0.23 11.1 11.4 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Med15 PF09606.5 CDI75288.1 - 0.25 9.4 39.8 0.31 9.2 27.6 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal R_equi_Vir PF05526.6 CDI75288.1 - 0.31 10.6 10.7 0.38 10.3 7.4 1.1 1 0 0 1 1 1 0 Rhodococcus equi virulence-associated protein DUF2828 PF11443.3 CDI75288.1 - 0.45 8.6 7.3 0.52 8.4 5.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) DUF106 PF01956.11 CDI75288.1 - 0.58 9.6 4.8 0.71 9.3 3.3 1.1 1 0 0 1 1 1 0 Integral membrane protein DUF106 HemX PF04375.9 CDI75288.1 - 0.77 8.2 22.1 0.9 8.0 15.3 1.1 1 0 0 1 1 1 0 HemX AIF_C PF14721.1 CDI75288.1 - 0.79 9.9 9.6 1.1 9.5 6.7 1.2 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Glt_symporter PF03616.9 CDI75288.1 - 0.9 7.9 4.6 1.3 7.4 3.2 1.2 1 0 0 1 1 1 0 Sodium/glutamate symporter Peptidase_S49_N PF08496.5 CDI75288.1 - 0.9 9.3 9.0 1.2 8.9 6.2 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal SelP_N PF04592.9 CDI75288.1 - 1.1 8.6 19.6 1.3 8.3 13.6 1.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region DUF1980 PF09323.5 CDI75288.1 - 1.1 8.9 7.1 1.4 8.6 4.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) DUF2232 PF09991.4 CDI75288.1 - 1.3 7.9 5.6 1.6 7.6 3.9 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) Lycopene_cycl PF05834.7 CDI75288.1 - 1.4 7.7 7.2 1.7 7.5 5.0 1.1 1 0 0 1 1 1 0 Lycopene cyclase protein Gag_spuma PF03276.9 CDI75288.1 - 1.5 7.0 23.9 1.8 6.7 16.6 1.0 1 0 0 1 1 1 0 Spumavirus gag protein Serinc PF03348.10 CDI75288.1 - 1.5 7.4 12.8 1.8 7.2 8.9 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) PAT1 PF09770.4 CDI75288.1 - 1.8 6.7 32.0 2 6.5 22.2 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Wzz PF02706.10 CDI75288.1 - 2 8.2 6.3 2.9 7.7 4.4 1.2 1 0 0 1 1 1 0 Chain length determinant protein DUF2956 PF11169.3 CDI75288.1 - 2.1 8.3 20.3 2.7 7.9 14.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2956) DUF4175 PF13779.1 CDI75288.1 - 2.2 5.8 31.6 2.6 5.6 21.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) OATP PF03137.15 CDI75288.1 - 2.4 6.0 8.5 3.1 5.7 5.9 1.2 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family TFIIA PF03153.8 CDI75288.1 - 2.5 7.9 28.4 2.9 7.7 19.7 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Hamartin PF04388.7 CDI75288.1 - 2.7 6.5 11.0 3.2 6.3 7.7 1.0 1 0 0 1 1 1 0 Hamartin protein CKAP2_C PF15297.1 CDI75288.1 - 2.8 6.6 13.7 3.2 6.4 9.5 1.0 1 0 0 1 1 1 0 Cytoskeleton-associated protein 2 C-terminus FLO_LFY PF01698.11 CDI75288.1 - 2.9 6.6 13.3 3.2 6.5 9.2 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein Macoilin PF09726.4 CDI75288.1 - 3 6.0 14.4 3.4 5.8 10.0 1.0 1 0 0 1 1 1 0 Transmembrane protein Zip PF02535.17 CDI75288.1 - 3.1 6.7 10.5 4 6.3 7.3 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter eIF-3_zeta PF05091.7 CDI75288.1 - 3.3 6.2 16.0 3.7 6.0 11.1 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Pal1 PF08316.6 CDI75288.1 - 3.4 8.1 9.8 4.6 7.6 6.8 1.1 1 0 0 1 1 1 0 Pal1 cell morphology protein DUF4557 PF15101.1 CDI75288.1 - 3.5 7.4 20.7 4.7 6.9 14.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) DUF3450 PF11932.3 CDI75288.1 - 3.6 6.7 26.1 4.9 6.3 18.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Pex16 PF08610.5 CDI75288.1 - 3.7 6.4 9.1 4.6 6.1 6.3 1.1 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) FAM222A PF15258.1 CDI75288.1 - 3.9 6.5 22.9 5 6.2 15.9 1.1 1 0 0 1 1 1 0 Protein family of FAM222A Peptidase_U57 PF05582.7 CDI75288.1 - 3.9 6.3 8.6 4.7 6.0 6.0 1.1 1 0 0 1 1 1 0 YabG peptidase U57 TCP PF03634.8 CDI75288.1 - 4 7.8 15.7 5.3 7.4 10.9 1.1 1 0 0 1 1 1 0 TCP family transcription factor AUX_IAA PF02309.11 CDI75288.1 - 4.8 6.8 10.0 5.8 6.5 6.9 1.1 1 0 0 1 1 1 0 AUX/IAA family DUF2215 PF10225.4 CDI75288.1 - 5.5 6.3 5.8 6.9 6.0 4.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) Band_3_cyto PF07565.8 CDI75288.1 - 5.8 6.3 11.8 7 6.0 8.2 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain GOLD_2 PF13897.1 CDI75288.1 - 6.2 7.0 6.3 8.5 6.6 4.4 1.2 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking Paramyxo_ncap PF00973.14 CDI75288.1 - 6.5 5.3 12.7 7.7 5.0 8.8 1.0 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Spc7_N PF15402.1 CDI75288.1 - 6.6 4.6 17.8 7.9 4.3 12.4 1.0 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 Neur_chan_memb PF02932.11 CDI75288.1 - 7.7 6.3 9.5 8.5 6.1 6.6 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Helicase_RecD PF05127.9 CDI75288.1 - 7.8 6.1 8.9 11 5.6 6.2 1.3 1 0 0 1 1 1 0 Helicase UPF0560 PF10577.4 CDI75288.1 - 8 4.5 21.0 9.3 4.3 14.6 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 DUF1387 PF07139.6 CDI75288.1 - 8.4 5.8 11.5 11 5.5 8.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) Ndc1_Nup PF09531.5 CDI75288.1 - 9.6 4.4 9.9 11 4.2 6.9 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Rhodanese PF00581.15 CDI75289.1 - 2.6 8.4 6.6 2.5 8.4 0.3 3.1 1 1 3 4 4 4 0 Rhodanese-like domain Dapper PF15268.1 CDI75289.1 - 4.5 5.9 58.3 6.1 5.5 40.4 1.1 1 0 0 1 1 1 0 Dapper Pribosyltran PF00156.22 CDI75289.1 - 7.8 6.2 9.4 3.7 7.2 3.0 2.9 2 1 0 2 2 2 0 Phosphoribosyl transferase domain DUF2217 PF10265.4 CDI75290.1 - 4.7 5.8 8.4 7 5.2 5.8 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) DUF3357 PF11837.3 CDI75292.1 - 0.13 12.1 5.8 0.51 10.2 0.0 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF3357) Utp14 PF04615.8 CDI75293.1 - 0.092 10.8 48.5 0.11 10.6 33.6 1.1 1 0 0 1 1 1 0 Utp14 protein Sporozoite_P67 PF05642.6 CDI75293.1 - 1.4 6.7 27.5 0.54 8.0 17.2 1.6 2 0 0 2 2 2 0 Sporozoite P67 surface antigen DUF572 PF04502.8 CDI75293.1 - 1.5 7.9 44.2 2.6 7.1 30.7 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF4551 PF15087.1 CDI75293.1 - 1.8 6.8 26.6 2.6 6.3 18.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) DUF966 PF06136.8 CDI75293.1 - 4.6 6.5 34.5 0.2 11.0 20.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF966) Plasmodium_Vir PF05795.6 CDI75293.1 - 7.6 5.6 18.4 0.65 9.1 1.0 2.4 2 0 0 2 2 2 0 Plasmodium vivax Vir protein MDMPI_N PF11716.3 CDI75294.1 - 1.3 9.4 27.1 1.6 9.1 18.8 1.1 1 0 0 1 1 1 0 Mycothiol maleylpyruvate isomerase N-terminal domain DUF1059 PF06348.6 CDI75295.1 - 0.098 12.4 0.1 0.23 11.3 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1059) MFS_Mycoplasma PF07672.8 CDI75295.1 - 0.96 8.5 6.5 8.9 5.3 0.0 4.3 3 0 0 3 3 3 0 Mycoplasma MFS transporter RskA PF10099.4 CDI75302.1 - 0.0031 17.2 7.8 0.0046 16.6 5.4 1.3 1 0 0 1 1 1 1 Anti-sigma-K factor rskA PA26 PF04636.8 CDI75302.1 - 0.24 10.0 12.0 0.26 9.9 8.3 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) MAT1 PF06391.8 CDI75302.1 - 0.35 10.4 10.8 0.44 10.1 7.5 1.1 1 0 0 1 1 1 0 CDK-activating kinase assembly factor MAT1 DUF2217 PF10265.4 CDI75302.1 - 0.4 9.4 22.2 0.56 8.9 15.4 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) Peptidase_U57 PF05582.7 CDI75302.1 - 0.46 9.4 6.6 0.59 9.0 4.6 1.2 1 0 0 1 1 1 0 YabG peptidase U57 Plasmodium_Vir PF05795.6 CDI75302.1 - 0.5 9.5 11.2 0.58 9.3 7.7 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein ARGLU PF15346.1 CDI75302.1 - 1.1 8.9 14.4 1.6 8.4 10.0 1.2 1 0 0 1 1 1 0 Arginine and glutamate-rich 1 SOBP PF15279.1 CDI75302.1 - 2.2 8.5 20.2 3.3 7.9 14.0 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein DUF1712 PF08217.6 CDI75302.1 - 2.9 6.0 14.8 3.3 5.8 10.3 1.1 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1712) CRT10 PF08728.5 CDI75302.1 - 3.1 5.6 15.2 3.2 5.6 10.5 1.0 1 0 0 1 1 1 0 CRT10 DUF3332 PF11810.3 CDI75302.1 - 3.9 7.1 6.3 6 6.4 4.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3332) Membralin PF09746.4 CDI75302.1 - 6.3 5.7 8.0 7.1 5.5 5.5 1.1 1 0 0 1 1 1 0 Tumour-associated protein ZYG-11_interact PF05884.7 CDI75302.1 - 7.4 5.5 11.3 9.7 5.1 7.8 1.2 1 0 0 1 1 1 0 Interactor of ZYG-11 DUF2215 PF10225.4 CDI75302.1 - 9.8 5.5 12.2 12 5.2 8.5 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) SR-25 PF10500.4 CDI75303.1 - 3.3e-05 23.4 14.8 4.1e-05 23.1 10.3 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein TIP_N PF12457.3 CDI75303.1 - 0.00013 21.9 11.1 0.00017 21.5 7.7 1.0 1 0 0 1 1 1 1 Tuftelin interacting protein N terminal Cwf_Cwc_15 PF04889.7 CDI75303.1 - 0.0064 16.2 8.2 0.0081 15.9 5.7 1.0 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein Prog_receptor PF02161.10 CDI75303.1 - 0.019 13.8 7.9 0.02 13.7 5.5 1.0 1 0 0 1 1 1 0 Progesterone receptor Period_C PF12114.3 CDI75303.1 - 0.037 13.6 12.9 0.038 13.6 9.0 1.1 1 0 0 1 1 1 0 Period protein 2/3C-terminal region RAB3GAP2_N PF14655.1 CDI75303.1 - 0.047 12.7 2.5 0.05 12.5 1.7 1.0 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Pex14_N PF04695.8 CDI75303.1 - 0.1 12.6 5.6 0.12 12.3 3.9 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Bul1_C PF04426.7 CDI75303.1 - 0.16 11.1 2.2 0.16 11.1 1.5 1.0 1 0 0 1 1 1 0 Bul1 C terminus CDK2AP PF09806.4 CDI75303.1 - 0.26 11.4 7.5 0.36 11.0 5.2 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein BNIP3 PF06553.7 CDI75303.1 - 0.44 9.9 11.1 0.51 9.6 7.7 1.0 1 0 0 1 1 1 0 BNIP3 Presenilin PF01080.12 CDI75303.1 - 0.47 9.2 4.6 0.53 9.0 3.2 1.0 1 0 0 1 1 1 0 Presenilin Phostensin_N PF13916.1 CDI75303.1 - 0.51 10.3 5.0 0.68 9.9 3.5 1.2 1 0 0 1 1 1 0 PP1-regulatory protein, Phostensin N-terminal NPR3 PF03666.8 CDI75303.1 - 0.73 8.2 4.3 0.85 8.0 3.0 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 CDC45 PF02724.9 CDI75303.1 - 0.81 7.6 7.6 0.92 7.4 5.3 1.0 1 0 0 1 1 1 0 CDC45-like protein DDHD PF02862.12 CDI75303.1 - 0.94 9.2 7.8 1 9.1 5.4 1.0 1 0 0 1 1 1 0 DDHD domain Spore_coat_CotO PF14153.1 CDI75303.1 - 1 8.7 9.4 1.2 8.5 6.5 1.0 1 0 0 1 1 1 0 Spore coat protein CotO PBP_sp32 PF07222.7 CDI75303.1 - 1.2 8.2 8.1 1.3 8.1 5.6 1.1 1 0 0 1 1 1 0 Proacrosin binding protein sp32 DUF508 PF04370.7 CDI75303.1 - 1.6 8.3 6.3 1.9 8.1 4.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF508) DUF4614 PF15391.1 CDI75303.1 - 1.9 8.2 12.1 2 8.1 8.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) Apt1 PF10351.4 CDI75303.1 - 2.7 6.7 10.6 3.1 6.5 7.3 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF515 PF04415.7 CDI75303.1 - 2.8 6.0 12.6 3 5.9 8.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Serinc PF03348.10 CDI75303.1 - 3.4 6.2 5.5 3.7 6.1 3.8 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) MRI PF15325.1 CDI75303.1 - 6 7.8 11.1 7.7 7.5 7.7 1.1 1 0 0 1 1 1 0 Modulator of retrovirus infection MIP-T3 PF10243.4 CDI75304.1 - 3.2e-10 39.1 63.3 3.2e-10 39.1 43.9 4.4 4 1 0 4 4 4 3 Microtubule-binding protein MIP-T3 DUF4175 PF13779.1 CDI75305.1 - 3.7e-05 21.6 64.4 3.7e-05 21.6 44.7 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4175) CRT10 PF08728.5 CDI75305.1 - 5 5.0 14.3 4.8 5.0 9.9 1.1 1 0 0 1 1 1 0 CRT10 DDHD PF02862.12 CDI75306.1 - 1.1 9.0 63.6 0.24 11.1 8.5 3.2 3 0 0 3 3 3 0 DDHD domain CAF-1_p150 PF11600.3 CDI75306.1 - 2.4 7.5 81.4 0.022 14.1 13.5 3.2 3 0 0 3 3 3 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Raftlin PF15250.1 CDI75306.1 - 3.6 6.0 56.5 0.25 9.7 10.0 3.1 3 0 0 3 3 3 0 Raftlin CDC45 PF02724.9 CDI75307.1 - 0.073 11.1 40.5 0.094 10.7 28.1 1.3 1 0 0 1 1 1 0 CDC45-like protein SAGA-Tad1 PF12767.2 CDI75307.1 - 0.11 12.1 27.3 0.14 11.7 18.9 1.2 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit PAT1 PF09770.4 CDI75307.1 - 0.24 9.5 53.2 0.28 9.3 36.9 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 GAGA_bind PF06217.7 CDI75307.1 - 1.5 8.7 33.9 1.9 8.3 23.5 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family CENP-T PF15511.1 CDI75307.1 - 2.6 7.2 40.1 3.1 6.9 27.8 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T eIF-3_zeta PF05091.7 CDI75307.1 - 3.1 6.2 33.1 4.6 5.7 22.9 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Lin-8 PF03353.10 CDI75307.1 - 4 6.6 42.1 4.7 6.4 29.2 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist CDC27 PF09507.5 CDI75307.1 - 5.9 6.0 46.2 7.1 5.7 32.0 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Dapper PF15268.1 CDI75307.1 - 7.9 5.1 35.9 8.8 4.9 24.9 1.1 1 0 0 1 1 1 0 Dapper Herpes_env PF01673.13 CDI75307.1 - 8.6 4.7 29.0 16 3.8 20.1 1.4 1 1 0 1 1 1 0 Herpesvirus putative major envelope glycoprotein PLRV_ORF5 PF01690.12 CDI75307.1 - 9 5.3 37.9 11 5.0 26.3 1.0 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Macoilin PF09726.4 CDI75310.1 - 0.011 14.1 12.9 0.02 13.1 8.9 1.4 1 0 0 1 1 1 0 Transmembrane protein Neur_chan_memb PF02932.11 CDI75313.1 - 9.7 5.9 14.2 2 8.2 0.2 2.3 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region UPF0564 PF10595.4 CDI75315.1 - 7.8e-05 21.7 10.3 9.6e-05 21.4 7.1 1.2 1 0 0 1 1 1 1 Uncharacterised protein family UPF0564 Med15 PF09606.5 CDI75315.1 - 0.00027 19.2 47.9 0.00031 19.1 33.2 1.1 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal DUF3357 PF11837.3 CDI75315.1 - 0.0014 18.4 10.6 0.002 17.9 1.5 2.9 3 1 0 3 3 3 1 Domain of unknown function (DUF3357) DUF605 PF04652.11 CDI75315.1 - 0.003 17.0 23.8 0.004 16.6 16.5 1.1 1 0 0 1 1 1 1 Vta1 like SR-25 PF10500.4 CDI75315.1 - 0.0079 15.6 0.5 0.0079 15.6 0.4 2.7 2 1 0 2 2 1 1 Nuclear RNA-splicing-associated protein Macoilin PF09726.4 CDI75315.1 - 0.026 12.8 18.5 0.035 12.4 12.9 1.1 1 0 0 1 1 1 0 Transmembrane protein CD20 PF04103.10 CDI75315.1 - 0.028 14.3 1.9 0.028 14.3 1.3 2.8 2 1 1 3 3 3 0 CD20-like family PAT1 PF09770.4 CDI75315.1 - 0.081 11.1 40.4 0.11 10.7 28.0 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Cytochrom_C_asm PF01578.15 CDI75315.1 - 0.12 11.9 0.9 0.63 9.5 0.1 2.1 2 0 0 2 2 2 0 Cytochrome C assembly protein FAM60A PF15396.1 CDI75315.1 - 0.21 11.2 12.8 0.077 12.7 3.1 2.2 2 0 0 2 2 2 0 Protein Family FAM60A HCO3_cotransp PF00955.16 CDI75315.1 - 0.28 9.7 3.9 0.39 9.3 2.7 1.1 1 0 0 1 1 1 0 HCO3- transporter family Spore_coat_CotO PF14153.1 CDI75315.1 - 0.54 9.6 16.3 0.9 8.9 11.3 1.4 1 0 0 1 1 1 0 Spore coat protein CotO Rxt3 PF08642.5 CDI75315.1 - 0.62 10.3 8.3 4.4 7.5 6.0 2.1 1 1 1 2 2 2 0 Histone deacetylation protein Rxt3 FLO_LFY PF01698.11 CDI75315.1 - 1.3 7.7 9.8 2.1 7.1 6.8 1.3 1 0 0 1 1 1 0 Floricaula / Leafy protein RR_TM4-6 PF06459.7 CDI75315.1 - 1.9 8.3 10.7 3.4 7.4 7.4 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Asp-B-Hydro_N PF05279.6 CDI75315.1 - 2.1 8.1 8.0 2.8 7.7 5.5 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region DUF1631 PF07793.6 CDI75315.1 - 2.6 6.0 32.2 3 5.8 22.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) Presenilin PF01080.12 CDI75315.1 - 3.5 6.3 12.5 0.5 9.1 4.9 1.9 2 0 0 2 2 2 0 Presenilin G-alpha PF00503.15 CDI75315.1 - 3.7 6.1 15.7 0.47 9.0 7.4 1.8 2 0 0 2 2 2 0 G-protein alpha subunit Claudin_2 PF13903.1 CDI75315.1 - 6.9 6.3 22.9 1e+03 -0.8 15.9 2.4 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction EphA2_TM PF14575.1 CDI75315.1 - 7.8 6.9 15.1 0.082 13.3 1.5 3.0 2 1 1 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain AAA_23 PF13476.1 CDI75315.1 - 7.9 6.7 19.0 13 6.0 13.2 1.3 1 0 0 1 1 1 0 AAA domain Zip PF02535.17 CDI75316.1 - 0.11 11.4 18.0 0.34 9.8 0.0 3.5 3 1 0 3 3 3 0 ZIP Zinc transporter LMBR1 PF04791.11 CDI75316.1 - 9.1 4.7 18.5 0.044 12.3 2.1 3.6 2 2 1 3 3 3 0 LMBR1-like membrane protein PIG-P PF08510.7 CDI75318.1 - 0.0033 17.0 0.1 0.12 11.9 0.0 2.4 2 0 0 2 2 2 1 PIG-P PAS PF00989.19 CDI75318.1 - 0.009 15.7 4.4 0.044 13.5 0.2 2.2 2 0 0 2 2 2 1 PAS fold Zn_peptidase PF04228.8 CDI75318.1 - 0.0095 15.1 0.7 0.0095 15.1 0.5 2.6 2 1 1 3 3 3 1 Putative neutral zinc metallopeptidase Peptidase_S49_N PF08496.5 CDI75318.1 - 0.036 13.8 12.2 0.22 11.2 0.9 3.3 4 0 0 4 4 4 0 Peptidase family S49 N-terminal Ribosomal_60s PF00428.14 CDI75318.1 - 0.72 10.2 18.8 0.55 10.6 3.7 2.4 2 0 0 2 2 2 0 60s Acidic ribosomal protein Peptidase_C12 PF01088.16 CDI75318.1 - 1.1 8.4 13.1 2.3 7.3 1.5 2.7 2 0 0 2 2 2 0 Ubiquitin carboxyl-terminal hydrolase, family 1 DUF2722 PF10846.3 CDI75318.1 - 4 6.3 41.3 0.02 13.9 1.4 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2722) FAM176 PF14851.1 CDI75318.1 - 6.6 6.4 14.9 12 5.5 0.0 3.5 4 0 0 4 4 4 0 FAM176 family Anoctamin PF04547.7 CDI75318.1 - 7.3 5.1 10.4 17 3.9 4.0 2.4 2 0 0 2 2 2 0 Calcium-activated chloride channel DUF2149 PF09919.4 CDI75318.1 - 8.6 6.5 10.6 4.8 7.3 1.2 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2149) Herpes_UL6 PF01763.11 CDI75321.1 - 0.71 7.9 11.3 1.5 6.9 7.8 1.5 1 0 0 1 1 1 0 Herpesvirus UL6 like PAT1 PF09770.4 CDI75322.1 - 0.28 9.3 60.4 0.32 9.1 41.9 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 GAGA_bind PF06217.7 CDI75322.1 - 5.4 6.9 25.7 7.6 6.4 17.8 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family OAD_gamma PF04277.8 CDI75327.1 - 0.5 10.7 0.0 0.5 10.7 0.0 5.4 3 2 1 4 4 4 0 Oxaloacetate decarboxylase, gamma chain BAF1_ABF1 PF04684.8 CDI75328.1 - 0.0016 17.4 14.7 0.0016 17.4 10.2 7.8 1 1 6 8 8 8 2 BAF1 / ABF1 chromatin reorganising factor DEAD PF00270.24 CDI75329.1 - 9.3e-26 90.3 0.0 1.4e-12 47.4 0.0 2.2 1 1 0 2 2 2 2 DEAD/DEAH box helicase AAA_22 PF13401.1 CDI75329.1 - 0.025 14.7 0.1 2.8 8.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain Glyco_transf_90 PF05686.7 CDI75331.1 - 4.5e-68 229.7 0.0 6.2e-68 229.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 90 Thioredoxin PF00085.15 CDI75331.1 - 1.2e-41 140.6 0.0 8.3e-22 76.8 0.0 3.4 3 0 0 3 3 3 3 Thioredoxin Thioredoxin_2 PF13098.1 CDI75331.1 - 8.2e-11 42.0 0.8 0.0006 19.9 0.1 3.9 2 2 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_7 PF13899.1 CDI75331.1 - 3e-09 36.7 0.0 0.00093 19.1 0.0 2.9 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_9 PF14595.1 CDI75331.1 - 7.7e-05 22.2 0.2 0.027 14.0 0.0 3.1 3 0 0 3 3 3 1 Thioredoxin Thioredoxin_6 PF13848.1 CDI75331.1 - 0.00028 20.7 0.0 0.11 12.3 0.0 2.9 3 0 0 3 3 3 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 CDI75331.1 - 0.00068 19.7 0.2 4.3 7.5 0.0 3.8 3 1 1 4 4 4 2 Thioredoxin-like Glyco_trans_1_2 PF13524.1 CDI75331.1 - 0.00071 19.7 0.0 0.0021 18.2 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 ERp29_N PF07912.8 CDI75331.1 - 0.0032 17.4 0.0 0.04 13.8 0.0 2.3 2 0 0 2 2 2 1 ERp29, N-terminal domain Redoxin PF08534.5 CDI75331.1 - 0.078 12.5 0.0 4.3 6.8 0.0 3.0 3 0 0 3 3 3 0 Redoxin Glutaredoxin PF00462.19 CDI75331.1 - 0.081 12.9 0.0 8.6 6.4 0.0 2.9 2 0 0 2 2 2 0 Glutaredoxin Filamin PF00630.14 CDI75331.1 - 0.17 12.4 0.0 0.34 11.4 0.0 1.4 1 0 0 1 1 1 0 Filamin/ABP280 repeat EF-hand_1 PF00036.27 CDI75333.1 - 3.5e-27 91.5 5.0 2.4e-07 29.5 0.1 4.5 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 CDI75333.1 - 2.4e-25 88.4 2.0 2.6e-12 46.6 0.4 2.7 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.1 CDI75333.1 - 4.5e-25 85.8 1.5 9.1e-07 27.9 0.1 4.8 5 0 0 5 5 5 4 EF hand EF-hand_6 PF13405.1 CDI75333.1 - 7.9e-20 68.9 4.2 0.0012 18.5 0.0 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.1 CDI75333.1 - 4.6e-15 54.9 6.4 1.6e-05 24.3 1.3 4.6 3 1 1 4 4 4 3 EF-hand domain pair SPARC_Ca_bdg PF10591.4 CDI75333.1 - 4.1e-09 36.4 0.0 0.0013 18.7 0.0 2.2 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 CDI75333.1 - 3.7e-05 23.4 2.4 0.12 12.0 0.3 3.2 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.1 CDI75333.1 - 0.00056 19.7 0.1 0.02 14.7 0.0 3.0 3 0 0 3 3 3 1 EF-hand domain Caleosin PF05042.8 CDI75333.1 - 0.063 12.8 0.5 5.2 6.5 0.0 3.0 2 1 2 4 4 4 0 Caleosin related protein VCBS PF13517.1 CDI75333.1 - 0.27 11.6 3.2 0.4 11.0 0.2 2.6 2 1 0 2 2 2 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella PUB PF09409.5 CDI75334.1 - 0.00024 20.7 0.0 0.00045 19.9 0.0 1.4 1 0 0 1 1 1 1 PUB domain Asp PF00026.18 CDI75334.1 - 0.053 12.7 0.0 0.072 12.3 0.0 1.2 1 0 0 1 1 1 0 Eukaryotic aspartyl protease Mito_carr PF00153.22 CDI75335.1 - 1.9e-37 126.8 0.8 2.9e-15 55.7 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein NicO PF03824.11 CDI75337.1 - 0.58 9.4 8.5 2.4 7.4 5.9 2.0 1 0 0 1 1 1 0 High-affinity nickel-transport protein Arc_PepC PF06819.6 CDI75338.1 - 0.12 12.3 0.0 0.31 10.9 0.0 1.7 1 0 0 1 1 1 0 Archaeal Peptidase A24 C-terminal Domain CbiA PF01656.18 CDI75339.1 - 5.1e-08 32.5 0.0 1.2e-07 31.3 0.0 1.6 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ArsA_ATPase PF02374.10 CDI75339.1 - 3.5e-05 23.0 0.2 3.5e-05 23.0 0.1 2.3 2 1 0 2 2 2 1 Anion-transporting ATPase MipZ PF09140.6 CDI75339.1 - 0.00018 20.6 0.1 0.0011 18.0 0.0 1.9 2 0 0 2 2 2 1 ATPase MipZ YhjQ PF06564.7 CDI75339.1 - 0.0003 20.2 1.6 0.0018 17.6 0.0 2.1 2 0 0 2 2 2 1 YhjQ protein AAA_31 PF13614.1 CDI75339.1 - 0.00045 20.1 0.1 0.0011 18.9 0.0 1.6 2 0 0 2 2 1 1 AAA domain DUF258 PF03193.11 CDI75339.1 - 0.00086 18.5 0.0 0.0015 17.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 G-alpha PF00503.15 CDI75339.1 - 0.0009 18.0 0.7 0.0012 17.5 0.5 1.1 1 0 0 1 1 1 1 G-protein alpha subunit Shadoo PF14999.1 CDI75339.1 - 0.0018 18.1 13.5 0.21 11.4 0.1 2.3 2 0 0 2 2 2 2 Shadow of prion protein, neuroprotective AAA_17 PF13207.1 CDI75339.1 - 0.0044 17.8 0.0 0.0069 17.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.17 CDI75339.1 - 0.0061 15.4 0.1 0.0061 15.4 0.0 1.4 2 0 0 2 2 1 1 NB-ARC domain T2SE PF00437.15 CDI75339.1 - 0.007 15.3 0.0 0.007 15.3 0.0 1.4 2 0 0 2 2 2 1 Type II/IV secretion system protein Herpes_DNAp_acc PF04929.7 CDI75339.1 - 0.0074 15.2 0.7 0.012 14.5 0.5 1.3 1 0 0 1 1 1 1 Herpes DNA replication accessory factor ArgK PF03308.11 CDI75339.1 - 0.0081 14.9 0.8 0.026 13.3 0.0 2.0 2 0 0 2 2 2 1 ArgK protein APS_kinase PF01583.15 CDI75339.1 - 0.0095 15.6 0.0 0.016 14.8 0.0 1.4 1 0 0 1 1 1 1 Adenylylsulphate kinase KTI12 PF08433.5 CDI75339.1 - 0.018 14.2 0.9 0.077 12.1 0.0 2.0 2 0 0 2 2 2 0 Chromatin associated protein KTI12 DUF1049 PF06305.6 CDI75339.1 - 0.022 14.2 2.1 0.043 13.2 1.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) CD20 PF04103.10 CDI75339.1 - 0.022 14.6 0.2 0.022 14.6 0.1 1.9 1 1 1 2 2 2 0 CD20-like family UPF0104 PF03706.8 CDI75339.1 - 0.023 13.9 0.7 0.18 11.0 0.1 1.9 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0104) AAA_25 PF13481.1 CDI75339.1 - 0.027 13.8 1.0 0.053 12.9 0.2 1.7 1 1 0 1 1 1 0 AAA domain RAB3GAP2_N PF14655.1 CDI75339.1 - 0.03 13.3 5.4 0.27 10.1 3.7 2.0 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus AAA_18 PF13238.1 CDI75339.1 - 0.043 14.1 0.8 0.061 13.6 0.0 1.6 2 0 0 2 2 1 0 AAA domain NTPase_1 PF03266.10 CDI75339.1 - 0.046 13.4 0.0 0.074 12.7 0.0 1.3 1 0 0 1 1 1 0 NTPase DUF3357 PF11837.3 CDI75339.1 - 0.049 13.4 0.3 0.17 11.7 0.0 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF3357) AAA_29 PF13555.1 CDI75339.1 - 0.058 12.9 0.0 0.16 11.5 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain Fer4_NifH PF00142.13 CDI75339.1 - 0.078 12.1 0.2 0.15 11.2 0.0 1.5 2 0 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family EphA2_TM PF14575.1 CDI75339.1 - 0.089 13.1 0.2 0.16 12.3 0.1 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF2512 PF10710.4 CDI75339.1 - 0.099 12.0 0.2 0.16 11.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2512) Rad17 PF03215.10 CDI75339.1 - 0.11 11.1 0.0 0.15 10.6 0.0 1.1 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein Spt20 PF12090.3 CDI75339.1 - 0.16 11.3 3.4 0.27 10.5 2.4 1.3 1 0 0 1 1 1 0 Spt20 family AAA_23 PF13476.1 CDI75339.1 - 0.21 11.9 8.6 0.97 9.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain DUF2489 PF10675.4 CDI75339.1 - 0.25 11.0 8.9 0.46 10.1 6.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2489) DUF4367 PF14285.1 CDI75339.1 - 0.32 10.3 2.1 3.3 7.0 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4367) Oleosin PF01277.12 CDI75339.1 - 0.33 10.5 0.1 0.33 10.5 0.1 2.0 3 0 0 3 3 2 0 Oleosin AAA_22 PF13401.1 CDI75339.1 - 0.61 10.2 2.9 0.54 10.3 0.3 2.0 1 1 1 2 2 2 0 AAA domain DUF2681 PF10883.3 CDI75339.1 - 0.71 10.1 14.7 0.11 12.6 6.7 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) CcmD PF04995.9 CDI75339.1 - 0.74 9.5 4.3 2 8.2 3.0 1.7 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) IstB_IS21 PF01695.12 CDI75339.1 - 1.1 8.6 5.9 2 7.7 0.0 2.2 2 0 0 2 2 2 0 IstB-like ATP binding protein FxsA PF04186.8 CDI75339.1 - 1.2 8.7 3.5 2.6 7.6 2.4 1.6 1 1 0 1 1 1 0 FxsA cytoplasmic membrane protein Ctr PF04145.10 CDI75339.1 - 1.3 9.0 3.6 2.2 8.3 2.5 1.5 1 1 0 1 1 1 0 Ctr copper transporter family PAT1 PF09770.4 CDI75339.1 - 2 6.5 14.2 2.5 6.2 9.8 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Abhydrolase_5 PF12695.2 CDI75339.1 - 2.9 7.6 8.5 5.4 6.7 5.5 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase family FHIPEP PF00771.15 CDI75339.1 - 4 5.6 6.5 1.1 7.4 2.4 1.4 1 1 1 2 2 2 0 FHIPEP family DNA_pol_alpha_N PF12254.3 CDI75340.1 - 5.3e-15 54.9 8.7 2.4e-14 52.8 6.0 2.2 1 0 0 1 1 1 1 DNA polymerase alpha subunit p180 N terminal RBM39linker PF15519.1 CDI75340.1 - 5.2 7.4 8.1 0.3 11.4 0.2 3.0 2 1 0 2 2 2 0 linker between RRM2 and RRM3 domains in RBM39 protein CDC27 PF09507.5 CDI75341.1 - 1.8 7.6 53.4 2.5 7.2 37.0 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 DUF3357 PF11837.3 CDI75341.1 - 5.2 6.9 15.6 1.8 8.4 2.7 3.8 1 1 3 4 4 4 0 Domain of unknown function (DUF3357) Chloroa_b-bind PF00504.16 CDI75341.1 - 9.5 6.4 9.6 12 6.1 6.1 1.7 1 1 0 1 1 1 0 Chlorophyll A-B binding protein Bac_Ubq_Cox PF01654.12 CDI75341.1 - 9.6 4.4 10.2 13 4.0 7.1 1.2 1 0 0 1 1 1 0 Bacterial Cytochrome Ubiquinol Oxidase DUF1510 PF07423.6 CDI75343.1 - 0.095 12.0 19.9 0.11 11.9 13.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DUF3260 PF11658.3 CDI75343.1 - 0.21 9.6 19.0 0.24 9.4 13.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3260) Rtf2 PF04641.7 CDI75343.1 - 0.32 10.1 16.6 0.34 10.0 11.5 1.0 1 0 0 1 1 1 0 Rtf2 RING-finger YABBY PF04690.8 CDI75343.1 - 0.36 11.0 15.3 0.44 10.7 10.6 1.1 1 0 0 1 1 1 0 YABBY protein Folate_carrier PF01770.13 CDI75343.1 - 0.38 9.2 13.4 0.44 8.9 9.3 1.1 1 0 0 1 1 1 0 Reduced folate carrier Neur_chan_memb PF02932.11 CDI75343.1 - 0.4 10.5 22.5 0.43 10.4 15.6 1.0 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region UPF0565 PF10561.4 CDI75343.1 - 0.59 8.9 17.9 0.68 8.7 12.4 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0565 Mem_trans PF03547.13 CDI75343.1 - 0.69 8.1 12.1 0.75 8.0 8.4 1.0 1 0 0 1 1 1 0 Membrane transport protein FAM176 PF14851.1 CDI75343.1 - 0.83 9.3 10.6 1.3 8.6 7.4 1.3 1 1 0 1 1 1 0 FAM176 family Neur PF00064.13 CDI75343.1 - 1.1 7.2 5.8 1.2 7.1 4.0 1.0 1 0 0 1 1 1 0 Neuraminidase Pox_Ag35 PF03286.9 CDI75343.1 - 1.2 8.6 10.7 1.3 8.5 7.4 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Tim54 PF11711.3 CDI75343.1 - 1.3 7.5 13.1 1.4 7.4 9.1 1.0 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DUF2052 PF09747.4 CDI75343.1 - 1.3 8.8 25.0 1.6 8.5 17.3 1.1 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) FAM60A PF15396.1 CDI75343.1 - 1.4 8.5 18.0 1.5 8.5 12.5 1.0 1 0 0 1 1 1 0 Protein Family FAM60A Serinc PF03348.10 CDI75343.1 - 2.1 6.9 15.4 2.4 6.7 10.7 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) SID-1_RNA_chan PF13965.1 CDI75343.1 - 3.6 5.6 11.3 4 5.4 7.9 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Pex16 PF08610.5 CDI75343.1 - 3.7 6.4 19.0 5.3 5.9 13.1 1.3 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) Herpes_DNAp_acc PF04929.7 CDI75343.1 - 3.7 6.4 16.7 4.3 6.2 11.6 1.0 1 0 0 1 1 1 0 Herpes DNA replication accessory factor DUF2232 PF09991.4 CDI75343.1 - 3.8 6.4 6.3 4.4 6.2 4.3 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) Baculo_PP31 PF05311.6 CDI75343.1 - 4.6 6.4 18.9 6.5 5.9 13.1 1.3 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) DUF853 PF05872.7 CDI75343.1 - 5 5.3 13.4 5.8 5.1 9.3 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) CDC45 PF02724.9 CDI75343.1 - 5.8 4.8 20.2 6.9 4.5 14.0 1.0 1 0 0 1 1 1 0 CDC45-like protein DUF4446 PF14584.1 CDI75343.1 - 6.1 6.6 12.3 7.3 6.3 8.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) PAT1 PF09770.4 CDI75343.1 - 6.2 4.9 54.5 6.1 4.9 37.8 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 AUX_IAA PF02309.11 CDI75343.1 - 6.3 6.4 18.0 7.1 6.3 12.5 1.1 1 0 0 1 1 1 0 AUX/IAA family Spore_coat_CotO PF14153.1 CDI75343.1 - 6.7 6.0 32.8 8.4 5.7 22.7 1.0 1 0 0 1 1 1 0 Spore coat protein CotO DUF4045 PF13254.1 CDI75343.1 - 6.9 5.8 19.6 7.3 5.7 13.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Plasmodium_Vir PF05795.6 CDI75343.1 - 7.2 5.7 8.1 7.1 5.7 5.6 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein FLO_LFY PF01698.11 CDI75343.1 - 7.8 5.2 21.3 9 5.0 14.7 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein DDHD PF02862.12 CDI75343.1 - 8.3 6.1 18.3 10 5.8 12.7 1.1 1 0 0 1 1 1 0 DDHD domain CKAP2_C PF15297.1 CDI75343.1 - 8.4 5.0 23.3 9.4 4.9 16.1 1.0 1 0 0 1 1 1 0 Cytoskeleton-associated protein 2 C-terminus Raftlin PF15250.1 CDI75343.1 - 8.5 4.7 22.3 8.9 4.7 15.5 1.0 1 0 0 1 1 1 0 Raftlin Hid1 PF12722.2 CDI75343.1 - 8.9 3.8 24.0 9.2 3.7 16.6 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Ycf1 PF05758.7 CDI75343.1 - 9.2 3.8 22.0 9.4 3.7 15.3 1.0 1 0 0 1 1 1 0 Ycf1 FHIPEP PF00771.15 CDI75343.1 - 9.2 4.4 13.5 11 4.1 9.3 1.2 1 0 0 1 1 1 0 FHIPEP family Herpes_UL87 PF03043.9 CDI75343.1 - 9.4 4.4 14.9 10 4.3 10.3 1.0 1 0 0 1 1 1 0 Herpesvirus UL87 family DUF936 PF06075.7 CDI75344.1 - 7.6e-05 21.8 28.2 7.6e-05 21.8 19.5 2.2 2 0 0 2 2 2 2 Plant protein of unknown function (DUF936) Pex14_N PF04695.8 CDI75345.1 - 0.061 13.3 12.8 0.078 13.0 8.8 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF4614 PF15391.1 CDI75345.1 - 0.22 11.2 17.7 0.25 11.1 12.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) Secretin_N_2 PF07655.8 CDI75345.1 - 0.93 9.9 26.3 1.3 9.4 18.3 1.2 1 0 0 1 1 1 0 Secretin N-terminal domain Band_3_cyto PF07565.8 CDI75345.1 - 1.2 8.6 4.6 1.2 8.6 3.2 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Bul1_C PF04426.7 CDI75345.1 - 1.5 7.9 7.3 1.7 7.7 5.1 1.1 1 0 0 1 1 1 0 Bul1 C terminus DUF966 PF06136.8 CDI75345.1 - 2.1 7.6 16.5 2.2 7.5 11.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Hid1 PF12722.2 CDI75345.1 - 2.5 5.6 9.4 2.5 5.6 6.5 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein NST1 PF13945.1 CDI75345.1 - 3.1 7.8 11.9 3.5 7.6 8.3 1.1 1 0 0 1 1 1 0 Salt tolerance down-regulator Apt1 PF10351.4 CDI75345.1 - 3.4 6.4 14.1 3.6 6.3 9.8 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain Rifin_STEVOR PF02009.11 CDI75345.1 - 4 6.9 11.9 4.6 6.7 8.3 1.1 1 0 0 1 1 1 0 Rifin/stevor family Corona_nucleoca PF00937.13 CDI75345.1 - 4.8 6.0 19.0 5.2 5.9 13.2 1.1 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein FGF-BP1 PF06473.7 CDI75345.1 - 5.2 6.5 8.9 6.2 6.3 6.2 1.1 1 0 0 1 1 1 0 FGF binding protein 1 (FGF-BP1) DUF4551 PF15087.1 CDI75345.1 - 5.3 5.2 10.8 5.9 5.1 7.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Sec3_C PF09763.4 CDI75345.1 - 8.1 4.4 9.8 8.1 4.4 6.8 1.0 1 0 0 1 1 1 0 Exocyst complex component Sec3 Macoilin PF09726.4 CDI75345.1 - 8.3 4.5 24.2 8.8 4.4 16.8 1.0 1 0 0 1 1 1 0 Transmembrane protein Senescence_reg PF04520.8 CDI75345.1 - 8.8 6.8 11.2 12 6.3 7.8 1.2 1 0 0 1 1 1 0 Senescence regulator BAF1_ABF1 PF04684.8 CDI75345.1 - 9.3 4.9 10.4 12 4.5 7.2 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor SprA-related PF12118.3 CDI75346.1 - 0.0046 16.3 19.9 0.0058 16.0 13.8 1.1 1 0 0 1 1 1 1 SprA-related family Senescence_reg PF04520.8 CDI75346.1 - 0.22 12.0 12.9 0.3 11.5 8.9 1.2 1 0 0 1 1 1 0 Senescence regulator Suf PF05843.9 CDI75346.1 - 0.67 9.6 9.8 0.83 9.3 6.8 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) SOBP PF15279.1 CDI75346.1 - 0.71 10.2 19.7 0.83 9.9 13.6 1.0 1 0 0 1 1 1 0 Sine oculis-binding protein TFIIA PF03153.8 CDI75346.1 - 2.1 8.1 17.8 2.5 7.9 12.3 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4349 PF14257.1 CDI75346.1 - 2.1 7.4 13.7 2.5 7.2 9.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) CDC45 PF02724.9 CDI75346.1 - 2.8 5.8 20.0 3.6 5.5 13.9 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF572 PF04502.8 CDI75346.1 - 6.5 5.8 19.2 7.8 5.6 13.3 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF1631 PF07793.6 CDI75346.1 - 7.1 4.6 11.6 7.6 4.5 8.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) Not1 PF04054.10 CDI75347.1 - 0.41 9.4 0.1 0.63 8.8 0.1 1.1 1 0 0 1 1 1 0 CCR4-Not complex component, Not1 Spore_coat_CotO PF14153.1 CDI75348.1 - 1.6e-05 24.4 8.1 1.7e-05 24.3 5.6 1.2 1 0 0 1 1 1 1 Spore coat protein CotO Ycf1 PF05758.7 CDI75348.1 - 7.2e-05 20.7 3.3 7.2e-05 20.7 2.3 1.0 1 0 0 1 1 1 1 Ycf1 Hom_end_hint PF05203.11 CDI75348.1 - 0.0016 18.1 2.9 0.0017 18.1 2.0 1.2 1 0 0 1 1 1 1 Hom_end-associated Hint Plasmodium_Vir PF05795.6 CDI75348.1 - 0.011 14.9 1.2 0.011 14.9 0.8 1.7 2 0 0 2 2 2 0 Plasmodium vivax Vir protein DUF4637 PF15470.1 CDI75348.1 - 0.014 15.0 4.8 0.024 14.2 3.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) CDC45 PF02724.9 CDI75348.1 - 0.03 12.3 7.3 0.033 12.2 5.0 1.1 1 0 0 1 1 1 0 CDC45-like protein Es2 PF09751.4 CDI75348.1 - 0.041 13.2 9.5 0.059 12.7 6.6 1.1 1 0 0 1 1 1 0 Nuclear protein Es2 Otopetrin PF03189.8 CDI75348.1 - 0.1 11.6 0.6 0.088 11.7 0.4 1.2 1 0 0 1 1 1 0 Otopetrin YjgP_YjgQ PF03739.9 CDI75348.1 - 0.16 10.7 1.3 0.16 10.6 0.9 1.2 1 0 0 1 1 1 0 Predicted permease YjgP/YjgQ family LMBR1 PF04791.11 CDI75348.1 - 0.31 9.5 1.6 0.3 9.6 1.1 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Borrelia_P83 PF05262.6 CDI75348.1 - 0.46 8.6 14.5 0.44 8.7 10.1 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein PAT1 PF09770.4 CDI75348.1 - 0.49 8.5 40.1 0.61 8.2 27.8 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 N6_N4_Mtase PF01555.13 CDI75348.1 - 0.7 9.3 3.4 0.94 8.9 2.4 1.2 1 0 0 1 1 1 0 DNA methylase DUF4045 PF13254.1 CDI75348.1 - 0.79 8.9 12.2 1 8.5 8.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Band_3_cyto PF07565.8 CDI75348.1 - 0.84 9.0 14.1 1.2 8.5 9.8 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Rtf2 PF04641.7 CDI75348.1 - 0.9 8.6 17.8 6.7 5.8 13.5 1.5 2 0 0 2 2 2 0 Rtf2 RING-finger Hid1 PF12722.2 CDI75348.1 - 0.91 7.1 13.4 1.3 6.6 9.3 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein AUX_IAA PF02309.11 CDI75348.1 - 1.3 8.7 20.3 1.9 8.1 13.9 1.4 1 1 0 1 1 1 0 AUX/IAA family Cellulose_synt PF03552.9 CDI75348.1 - 1.8 6.7 4.1 2.2 6.4 2.9 1.1 1 0 0 1 1 1 0 Cellulose synthase Neur_chan_memb PF02932.11 CDI75348.1 - 1.9 8.2 12.2 1.3 8.8 5.9 2.0 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Gti1_Pac2 PF09729.4 CDI75348.1 - 2.1 8.1 8.4 3.3 7.5 5.8 1.3 1 0 0 1 1 1 0 Gti1/Pac2 family VP4_haemagglut PF00426.13 CDI75348.1 - 3.4 5.5 9.0 4.5 5.1 6.2 1.1 1 0 0 1 1 1 0 Outer Capsid protein VP4 (Hemagglutinin) Spt20 PF12090.3 CDI75350.1 - 0.02 14.2 3.5 0.44 9.8 0.9 2.5 2 0 0 2 2 2 0 Spt20 family Spt20 PF12090.3 CDI75351.1 - 1.1 8.6 20.0 1.1 8.6 1.6 3.7 3 0 0 3 3 3 0 Spt20 family Glyco_hydro_35 PF01301.14 CDI75351.1 - 3.6 6.8 7.2 0.23 10.7 0.3 2.1 2 0 0 2 2 2 0 Glycosyl hydrolases family 35 CDK2AP PF09806.4 CDI75352.1 - 0.037 14.2 6.9 0.045 14.0 4.8 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein BAF1_ABF1 PF04684.8 CDI75352.1 - 5.7 5.6 13.0 10 4.8 9.0 1.5 1 1 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor SR-25 PF10500.4 CDI75354.1 - 0.022 14.2 17.8 0.023 14.1 12.4 1.0 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Glycophorin_A PF01102.13 CDI75354.1 - 2.8 7.7 10.9 3.1 7.5 7.6 1.1 1 0 0 1 1 1 0 Glycophorin A Hamartin PF04388.7 CDI75354.1 - 3.9 6.0 13.2 4 5.9 9.2 1.0 1 0 0 1 1 1 0 Hamartin protein Pol_alpha_B_N PF08418.5 CDI75356.1 - 0.0075 15.8 14.5 0.0075 15.8 10.0 3.2 2 1 0 2 2 2 1 DNA polymerase alpha subunit B N-terminal BRF1 PF07741.8 CDI75356.1 - 0.0085 16.2 3.6 0.0085 16.2 2.5 4.6 4 2 0 4 4 4 1 Brf1-like TBP-binding domain SeqA PF03925.8 CDI75356.1 - 0.018 14.7 1.3 0.018 14.7 0.9 3.7 4 0 0 4 4 4 0 SeqA protein Myosin_head PF00063.16 CDI75357.1 - 5.6e-13 47.8 0.1 5.6e-13 47.8 0.1 2.6 1 1 1 2 2 1 1 Myosin head (motor domain) AAA_19 PF13245.1 CDI75357.1 - 0.00097 18.8 0.0 0.0014 18.2 0.0 1.3 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 CDI75357.1 - 0.0016 18.5 0.1 0.0016 18.5 0.0 2.2 1 1 1 2 2 1 1 AAA domain AAA_16 PF13191.1 CDI75357.1 - 0.0057 16.6 0.9 0.0057 16.6 0.6 2.1 1 1 1 2 2 1 1 AAA ATPase domain AAA_18 PF13238.1 CDI75357.1 - 0.032 14.5 0.1 0.032 14.5 0.1 2.6 2 1 0 2 2 1 0 AAA domain SAPS PF04499.10 CDI75357.1 - 0.091 11.3 20.0 0.1 11.1 13.9 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Kinesin PF00225.18 CDI75357.1 - 0.1 11.2 19.6 0.15 10.6 13.6 1.2 1 0 0 1 1 1 0 Kinesin motor domain UPF0079 PF02367.12 CDI75357.1 - 0.13 11.8 0.0 0.13 11.8 0.0 2.3 1 1 1 2 2 1 0 Uncharacterised P-loop hydrolase UPF0079 Dicty_REP PF05086.7 CDI75357.1 - 0.22 9.2 18.5 0.22 9.2 12.8 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein PAT1 PF09770.4 CDI75357.1 - 0.29 9.3 61.4 0.33 9.1 42.6 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 RNA_helicase PF00910.17 CDI75357.1 - 0.44 10.7 0.0 0.44 10.7 0.0 2.3 2 1 0 2 2 1 0 RNA helicase SAGA-Tad1 PF12767.2 CDI75357.1 - 0.52 9.9 32.3 0.6 9.7 22.4 1.1 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit DUF1675 PF07897.6 CDI75357.1 - 0.83 9.4 19.3 0.89 9.3 13.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) CAF-1_p150 PF11600.3 CDI75357.1 - 1.2 8.5 35.4 1.3 8.3 24.5 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF1777 PF08648.7 CDI75357.1 - 1.2 8.8 24.5 1.4 8.5 17.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) Spore_coat_CotO PF14153.1 CDI75357.1 - 1.8 7.9 40.2 2 7.8 27.9 1.1 1 0 0 1 1 1 0 Spore coat protein CotO TFIIA PF03153.8 CDI75357.1 - 1.8 8.3 45.0 2.4 7.9 31.2 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Mem_trans PF03547.13 CDI75357.1 - 4 5.6 13.4 4.4 5.5 9.3 1.1 1 0 0 1 1 1 0 Membrane transport protein DUF4045 PF13254.1 CDI75357.1 - 4.1 6.5 26.4 4.5 6.4 18.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) BTV_NS2 PF04514.7 CDI75357.1 - 4.4 6.0 23.5 5.2 5.8 16.3 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 DUF572 PF04502.8 CDI75357.1 - 4.5 6.3 29.4 5.4 6.1 20.4 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF572) PLRV_ORF5 PF01690.12 CDI75357.1 - 4.6 6.2 24.5 5.4 6.0 17.0 1.0 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Membralin PF09746.4 CDI75357.1 - 5.2 6.0 11.6 5.7 5.8 8.0 1.1 1 0 0 1 1 1 0 Tumour-associated protein FLO_LFY PF01698.11 CDI75357.1 - 6.6 5.4 26.5 9.6 4.9 18.4 1.3 1 0 0 1 1 1 0 Floricaula / Leafy protein Exonuc_VII_L PF02601.10 CDI75357.1 - 6.8 5.7 26.7 7.7 5.6 18.5 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Raftlin PF15250.1 CDI75357.1 - 7.6 4.9 25.6 10 4.5 17.7 1.2 1 0 0 1 1 1 0 Raftlin AUX_IAA PF02309.11 CDI75357.1 - 9.6 5.8 24.2 14 5.3 16.8 1.3 1 0 0 1 1 1 0 AUX/IAA family LMBR1 PF04791.11 CDI75359.1 - 0.27 9.7 15.4 0.4 9.2 10.7 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Borrelia_P83 PF05262.6 CDI75359.1 - 2.4 6.3 34.9 3.4 5.8 24.2 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein PAT1 PF09770.4 CDI75359.1 - 4.3 5.4 94.4 4.7 5.3 65.0 1.3 1 1 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Septum_form PF13845.1 CDI75360.1 - 0.00056 19.4 5.5 0.00056 19.4 3.8 3.8 3 0 0 3 3 3 2 Septum formation DUF3357 PF11837.3 CDI75360.1 - 0.0055 16.5 1.0 0.0055 16.5 0.7 5.7 4 2 2 6 6 6 1 Domain of unknown function (DUF3357) ETRAMP PF09716.5 CDI75360.1 - 0.049 13.5 0.0 0.049 13.5 0.0 6.5 5 3 2 7 7 7 0 Malarial early transcribed membrane protein (ETRAMP) Mid2 PF04478.7 CDI75360.1 - 0.21 10.9 2.1 3.8 6.9 0.1 3.1 3 0 0 3 3 3 0 Mid2 like cell wall stress sensor 7TM_GPCR_Str PF10326.4 CDI75360.1 - 0.28 10.2 1.7 0.47 9.5 1.2 1.3 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Str BatD PF13584.1 CDI75360.1 - 4.6 5.7 15.3 0.023 13.2 4.1 1.9 2 0 0 2 2 2 0 Oxygen tolerance RskA PF10099.4 CDI75361.1 - 0.43 10.3 12.1 0.8 9.4 8.4 1.5 1 0 0 1 1 1 0 Anti-sigma-K factor rskA DUF2232 PF09991.4 CDI75361.1 - 6.2 5.7 5.8 8.7 5.2 4.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) Inositol_P PF00459.20 CDI75362.1 - 0.0058 15.9 0.0 0.0058 15.9 0.0 4.7 5 1 0 5 5 5 2 Inositol monophosphatase family GPCR_chapero_1 PF11904.3 CDI75362.1 - 9.3 5.2 26.4 39 3.2 12.7 3.2 3 0 0 3 3 3 0 GPCR-chaperone RNA_pol_Rpb1_1 PF04997.7 CDI75365.1 - 0.0084 15.4 0.0 0.0084 15.4 0.0 2.5 2 1 0 2 2 2 1 RNA polymerase Rpb1, domain 1 Tmemb_9 PF05434.6 CDI75365.1 - 0.027 14.2 0.1 0.027 14.2 0.1 3.3 2 1 1 3 3 3 0 TMEM9 PAT1 PF09770.4 CDI75365.1 - 0.12 10.5 29.0 0.15 10.2 20.1 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Med15 PF09606.5 CDI75365.1 - 0.74 7.9 34.8 0.94 7.5 24.1 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal EphA2_TM PF14575.1 CDI75365.1 - 3.4 8.1 7.0 57 4.2 2.2 3.3 3 0 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain ABC_membrane_3 PF13748.1 CDI75365.1 - 7.2 5.5 9.7 3.2 6.7 0.4 2.2 2 0 0 2 2 2 0 ABC transporter transmembrane region Pox_F17 PF04767.7 CDI75366.1 - 0.37 11.0 3.2 0.32 11.2 0.9 1.9 1 1 1 2 2 2 0 DNA-binding 11 kDa phosphoprotein Ribosomal_60s PF00428.14 CDI75367.1 - 0.056 13.8 0.1 0.2 12.0 0.0 2.0 2 0 0 2 2 2 0 60s Acidic ribosomal protein MIP-T3 PF10243.4 CDI75368.1 - 0.0031 16.0 26.6 0.0031 16.0 18.4 2.4 2 0 0 2 2 2 1 Microtubule-binding protein MIP-T3 Draxin PF15550.1 CDI75368.1 - 0.57 9.7 52.0 0.094 12.3 13.0 2.1 2 0 0 2 2 2 0 Draxin PLRV_ORF5 PF01690.12 CDI75368.1 - 5.5 6.0 63.8 0.19 10.8 15.6 2.1 2 0 0 2 2 2 0 Potato leaf roll virus readthrough protein DUF2981 PF11200.3 CDI75368.1 - 7.9 5.4 14.7 18 4.2 10.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) DUF2454 PF10521.4 CDI75369.1 - 0.0069 15.4 0.0 0.016 14.2 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2454) SRA1 PF07304.6 CDI75369.1 - 0.19 11.4 0.8 1.4 8.6 0.1 2.2 2 0 0 2 2 2 0 Steroid receptor RNA activator (SRA1) AAA_11 PF13086.1 CDI75370.1 - 7e-70 235.2 0.3 4.1e-69 232.7 0.0 2.4 2 1 0 2 2 2 1 AAA domain AAA_12 PF13087.1 CDI75370.1 - 7.4e-54 182.1 0.0 2.3e-53 180.5 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 CDI75370.1 - 9.2e-11 41.3 0.4 1.1e-05 25.1 0.0 3.4 3 0 0 3 3 3 2 Part of AAA domain AAA_30 PF13604.1 CDI75370.1 - 5.3e-07 29.4 4.6 0.0044 16.6 0.5 4.1 4 0 0 4 4 4 2 AAA domain Viral_helicase1 PF01443.13 CDI75370.1 - 0.001 18.6 0.1 0.043 13.3 0.0 2.7 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase UvrD-helicase PF00580.16 CDI75370.1 - 0.0073 15.6 0.0 2.8 7.1 0.1 3.4 3 1 1 4 4 4 1 UvrD/REP helicase N-terminal domain AAA_29 PF13555.1 CDI75370.1 - 0.13 11.7 0.1 0.31 10.6 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain RRM_1 PF00076.17 CDI75372.1 - 2.6e-37 126.2 0.2 2.5e-14 52.6 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CDI75372.1 - 7.1e-27 93.1 0.2 6.4e-10 38.8 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CDI75372.1 - 9.8e-26 89.3 0.0 1.2e-07 31.5 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 CDI75372.1 - 0.0058 16.4 0.4 2.7 7.9 0.0 3.2 3 0 0 3 3 3 2 RNA binding motif FUSC PF04632.7 CDI75372.1 - 4.6 5.5 6.4 8.9 4.6 4.4 1.4 1 0 0 1 1 1 0 Fusaric acid resistance protein family PIP5K PF01504.13 CDI75373.1 - 2.7e-62 210.1 0.0 4.6e-62 209.4 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase EF-hand_1 PF00036.27 CDI75373.1 - 0.00011 21.1 0.5 0.00043 19.3 0.1 2.3 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.1 CDI75373.1 - 0.0028 17.7 0.1 0.01 15.9 0.0 2.0 2 0 0 2 2 2 1 EF-hand domain pair DUF1319 PF07028.6 CDI75373.1 - 0.0039 17.3 1.5 0.0073 16.4 1.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1319) EF-hand_6 PF13405.1 CDI75373.1 - 0.012 15.4 0.1 0.064 13.1 0.0 2.3 1 0 0 1 1 1 0 EF-hand domain EF-hand_8 PF13833.1 CDI75373.1 - 0.021 14.4 3.2 0.2 11.3 0.4 2.7 2 0 0 2 2 2 0 EF-hand domain pair HXXSHH PF07586.6 CDI75373.1 - 0.05 12.5 0.8 0.086 11.7 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1552) Herpes_UL25 PF01499.11 CDI75373.1 - 0.59 8.3 2.6 0.87 7.8 1.8 1.2 1 0 0 1 1 1 0 Herpesvirus UL25 family zf-RING_2 PF13639.1 CDI75374.1 - 2.2e-07 30.5 9.4 5.7e-07 29.2 6.5 1.8 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 CDI75374.1 - 4.2e-07 29.8 8.7 9.8e-07 28.6 6.0 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CDI75374.1 - 6.9e-07 28.8 4.3 1.9e-06 27.4 3.0 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CDI75374.1 - 8.1e-07 28.5 7.3 2.1e-06 27.2 5.0 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CDI75374.1 - 1.1e-06 28.2 5.7 3.6e-06 26.5 4.0 2.0 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_6 PF14835.1 CDI75374.1 - 8e-05 22.3 1.9 0.00019 21.1 1.3 1.5 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-C3HC4_4 PF15227.1 CDI75374.1 - 0.0016 18.2 10.9 0.0016 18.2 7.5 2.3 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 CDI75374.1 - 0.0031 17.1 6.7 0.0097 15.6 4.6 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.2 CDI75374.1 - 0.037 14.1 1.3 0.13 12.4 0.9 2.0 1 0 0 1 1 1 0 RING-H2 zinc finger CpXC PF14353.1 CDI75374.1 - 0.1 12.5 0.2 0.1 12.5 0.1 4.0 4 0 0 4 4 4 0 CpXC protein GYD PF08734.6 CDI75374.1 - 0.87 9.3 6.0 0.12 12.1 0.3 2.5 2 0 0 2 2 2 0 GYD domain CAF-1_p150 PF11600.3 CDI75375.1 - 0.09 12.1 7.3 0.096 12.0 5.1 1.0 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF3027 PF11228.3 CDI75375.1 - 0.18 11.4 0.4 0.2 11.3 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3027) UPF0270 PF06794.7 CDI75375.1 - 0.27 11.0 5.0 0.56 9.9 3.4 1.7 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0270) SOXp PF12336.3 CDI75375.1 - 0.43 11.2 3.3 0.52 10.9 2.3 1.2 1 0 0 1 1 1 0 SOX transcription factor Med15 PF09606.5 CDI75375.1 - 2.6 6.1 26.5 2.4 6.2 18.4 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal CpXC PF14353.1 CDI75379.1 - 0.00044 20.2 2.1 0.00044 20.2 1.5 3.7 3 1 1 4 4 4 1 CpXC protein zf-C2H2 PF00096.21 CDI75379.1 - 0.0018 18.5 8.2 0.0029 17.8 5.7 1.3 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CDI75379.1 - 0.0063 16.7 4.3 0.011 15.9 3.0 1.4 1 0 0 1 1 1 1 C2H2-type zinc finger AAA_23 PF13476.1 CDI75379.1 - 0.0072 16.6 17.1 0.0072 16.6 11.8 2.3 2 0 0 2 2 2 2 AAA domain Activator_LAG-3 PF11498.3 CDI75379.1 - 0.098 11.3 68.6 0.014 14.1 7.2 2.6 2 0 0 2 2 2 0 Transcriptional activator LAG-3 zf-H2C2_2 PF13465.1 CDI75379.1 - 1.5 9.2 7.4 13 6.3 0.4 2.4 2 0 0 2 2 2 0 Zinc-finger double domain Dehydrin PF00257.14 CDI75380.1 - 0.014 15.7 7.3 0.014 15.7 5.1 7.3 5 2 1 6 6 6 0 Dehydrin CAF-1_p150 PF11600.3 CDI75381.1 - 0.05 12.9 27.8 0.068 12.5 19.3 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal SprA-related PF12118.3 CDI75381.1 - 0.055 12.7 49.6 0.065 12.5 34.4 1.0 1 0 0 1 1 1 0 SprA-related family RAP1 PF07218.6 CDI75381.1 - 0.064 11.3 7.6 0.063 11.3 5.2 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) HemX PF04375.9 CDI75381.1 - 0.1 11.1 33.1 0.12 10.9 22.9 1.0 1 0 0 1 1 1 0 HemX DUF4131 PF13567.1 CDI75381.1 - 0.13 11.6 5.0 0.2 11.0 3.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) DUF812 PF05667.6 CDI75381.1 - 0.57 8.6 26.1 0.68 8.3 18.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF812) PAT1 PF09770.4 CDI75381.1 - 0.74 7.9 45.4 0.88 7.7 31.5 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Med15 PF09606.5 CDI75381.1 - 1.4 7.0 59.0 1.4 6.9 40.9 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Herpes_UL87 PF03043.9 CDI75381.1 - 1.9 6.8 12.4 2.2 6.5 8.6 1.1 1 0 0 1 1 1 0 Herpesvirus UL87 family Dsh_C PF12316.3 CDI75381.1 - 4.2 7.4 25.6 5.5 7.0 17.8 1.2 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal DUF4175 PF13779.1 CDI75381.1 - 4.7 4.7 41.8 4.6 4.8 29.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) RskA PF10099.4 CDI75381.1 - 5.5 6.6 20.2 10 5.7 14.0 1.5 1 1 0 1 1 1 0 Anti-sigma-K factor rskA MelC1 PF06236.6 CDI75381.1 - 7.1 6.6 11.5 7.5 6.5 7.5 1.4 1 1 0 1 1 1 0 Tyrosinase co-factor MelC1 DUF966 PF06136.8 CDI75381.1 - 9.2 5.5 31.3 11 5.3 21.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Tetraspannin PF00335.15 CDI75383.1 - 0.037 13.2 6.1 0.051 12.8 4.3 1.1 1 0 0 1 1 1 0 Tetraspanin family Rifin_STEVOR PF02009.11 CDI75383.1 - 0.069 12.7 9.7 0.08 12.5 6.8 1.0 1 0 0 1 1 1 0 Rifin/stevor family Band_3_cyto PF07565.8 CDI75383.1 - 5.7 6.3 11.3 6.8 6.1 7.9 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain DUF3807 PF12720.2 CDI75383.1 - 7.1 6.7 9.9 9.4 6.3 6.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) DUF912 PF06024.7 CDI75383.1 - 7.9 6.6 9.3 79 3.3 6.4 2.2 1 1 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Ycf1 PF05758.7 CDI75384.1 - 0.00064 17.5 14.3 0.00064 17.5 9.9 5.2 3 2 2 5 5 5 1 Ycf1 Pox_Ag35 PF03286.9 CDI75384.1 - 0.00094 18.7 5.6 0.00094 18.7 3.9 7.0 6 1 0 6 6 6 2 Pox virus Ag35 surface protein LMBR1 PF04791.11 CDI75384.1 - 3 6.3 0.0 3 6.3 0.0 5.3 2 2 2 5 5 5 0 LMBR1-like membrane protein LRR_4 PF12799.2 CDI75385.1 - 0.00038 20.0 0.6 0.054 13.1 0.0 2.5 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 CDI75385.1 - 0.014 15.4 1.0 0.54 10.5 0.0 3.4 3 0 0 3 3 3 0 Leucine Rich repeat WD40 PF00400.27 CDI75386.1 - 0.00016 21.3 0.0 0.054 13.3 0.0 2.7 2 1 0 2 2 2 2 WD domain, G-beta repeat AP2 PF00847.15 CDI75387.1 - 0.01 15.9 0.9 0.017 15.2 0.6 1.4 1 0 0 1 1 1 0 AP2 domain AP2 PF00847.15 CDI75388.1 - 6e-20 71.1 5.7 4.4e-09 36.3 0.2 3.8 3 0 0 3 3 3 3 AP2 domain ACDC PF14733.1 CDI75388.1 - 0.1 12.7 0.0 0.23 11.6 0.0 1.6 1 0 0 1 1 1 0 AP2-coincident C-terminal Cut8_N PF14482.1 CDI75389.1 - 0.046 13.7 0.6 0.088 12.8 0.4 1.5 1 0 0 1 1 1 0 Cut8 proteasome-binding domain DUF1496 PF07383.7 CDI75389.1 - 0.16 11.2 0.3 0.26 10.5 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1496) Actin PF00022.14 CDI75390.1 - 1.8e-153 510.6 0.0 2e-153 510.4 0.0 1.0 1 0 0 1 1 1 1 Actin ESSS PF10183.4 CDI75390.1 - 0.13 12.6 0.0 0.46 10.8 0.0 1.8 1 1 1 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Pkinase PF00069.20 CDI75391.1 - 5.6e-50 169.9 0.0 8.4e-50 169.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDI75391.1 - 5.9e-42 143.5 0.0 8.3e-42 143.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CDI75391.1 - 0.015 14.2 0.0 0.029 13.3 0.0 1.4 1 0 0 1 1 1 0 Kinase-like RIO1 PF01163.17 CDI75391.1 - 0.021 14.1 0.0 0.037 13.3 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Med21 PF11221.3 CDI75394.1 - 0.00013 21.9 3.0 0.00054 19.9 2.1 1.8 1 1 0 1 1 1 1 Subunit 21 of Mediator complex UPF0184 PF03670.8 CDI75394.1 - 0.056 13.6 0.2 0.081 13.1 0.1 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0184) APG6 PF04111.7 CDI75394.1 - 0.073 12.1 2.0 0.087 11.8 1.4 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 V-SNARE PF05008.10 CDI75394.1 - 0.16 12.1 2.3 0.24 11.5 1.6 1.3 1 0 0 1 1 1 0 Vesicle transport v-SNARE protein N-terminus IncA PF04156.9 CDI75394.1 - 0.18 11.3 1.5 0.22 11.1 1.0 1.1 1 0 0 1 1 1 0 IncA protein Ubiq_cyt_C_chap PF03981.7 CDI75395.1 - 0.00042 20.1 0.1 0.0096 15.7 0.0 2.4 2 1 1 3 3 3 1 Ubiquinol-cytochrome C chaperone zf-DHHC PF01529.15 CDI75396.1 - 0.0061 15.9 0.8 0.033 13.5 0.1 2.0 2 0 0 2 2 2 1 DHHC palmitoyltransferase TB PF00683.12 CDI75396.1 - 0.04 13.4 0.8 0.075 12.6 0.6 1.3 1 0 0 1 1 1 0 TB domain SID-1_RNA_chan PF13965.1 CDI75396.1 - 0.05 11.7 0.5 0.056 11.6 0.3 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 PrgI PF12666.2 CDI75396.1 - 1.4 9.1 3.8 4.1 7.6 2.6 1.9 1 1 0 1 1 1 0 PrgI family protein IRK PF01007.15 CDI75398.1 - 0.0001 21.2 0.0 0.00019 20.3 0.0 1.4 1 1 0 1 1 1 1 Inward rectifier potassium channel Dpy-30 PF05186.8 CDI75399.1 - 4.3e-13 48.5 0.7 1.1e-12 47.1 0.5 1.8 1 0 0 1 1 1 1 Dpy-30 motif Sporozoite_P67 PF05642.6 CDI75401.1 - 1.4e-06 26.4 7.4 1.4e-06 26.4 5.1 6.5 2 2 1 4 4 4 1 Sporozoite P67 surface antigen Apc1 PF12859.2 CDI75402.1 - 0.039 14.1 0.2 0.039 14.1 0.1 3.6 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 1 ATP-grasp PF02222.17 CDI75402.1 - 0.094 12.0 0.1 0.094 12.0 0.1 3.5 3 1 1 4 4 4 0 ATP-grasp domain Afi1 PF07792.7 CDI75402.1 - 1.6 8.7 23.4 0.04 13.9 5.9 3.4 3 0 0 3 3 3 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Peptidase_S49_N PF08496.5 CDI75402.1 - 4.7 6.9 20.1 1.5 8.6 2.7 3.3 3 0 0 3 3 3 0 Peptidase family S49 N-terminal DUF4483 PF14825.1 CDI75403.1 - 0.11 12.2 4.6 0.17 11.5 3.2 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4483) Med15 PF09606.5 CDI75403.1 - 0.17 10.0 18.3 0.15 10.2 12.7 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Suf PF05843.9 CDI75403.1 - 4.1 7.0 6.8 4.3 6.9 4.7 1.0 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) RNase_H PF00075.19 CDI75404.1 - 0.042 14.1 2.5 0.054 13.8 1.7 1.2 1 0 0 1 1 1 0 RNase H DivIC PF04977.10 CDI75404.1 - 0.095 12.2 24.3 0.17 11.4 5.6 2.1 2 0 0 2 2 2 0 Septum formation initiator OmpH PF03938.9 CDI75404.1 - 0.13 12.1 27.8 0.15 11.9 19.3 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) FAM60A PF15396.1 CDI75404.1 - 0.24 11.1 4.8 0.23 11.1 3.3 1.1 1 0 0 1 1 1 0 Protein Family FAM60A Presenilin PF01080.12 CDI75404.1 - 0.58 8.9 2.4 0.59 8.8 1.7 1.0 1 0 0 1 1 1 0 Presenilin Pex16 PF08610.5 CDI75404.1 - 0.64 8.9 9.1 0.61 9.0 6.3 1.1 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) Slu7 PF11708.3 CDI75404.1 - 2.1 8.0 11.4 2.8 7.6 7.9 1.2 1 0 0 1 1 1 0 Pre-mRNA splicing Prp18-interacting factor Neur_chan_memb PF02932.11 CDI75404.1 - 2.1 8.1 4.2 2.4 8.0 2.9 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region UCH PF00443.24 CDI75404.1 - 2.9 6.9 12.5 2.7 7.0 8.7 1.1 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase DUF822 PF05687.8 CDI75404.1 - 3.3 8.0 12.0 4.5 7.6 8.3 1.2 1 0 0 1 1 1 0 Plant protein of unknown function (DUF822) PAT1 PF09770.4 CDI75404.1 - 4.8 5.2 38.2 5.5 5.0 26.5 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF106 PF01956.11 CDI75404.1 - 8.8 5.8 9.0 12 5.3 6.2 1.2 1 0 0 1 1 1 0 Integral membrane protein DUF106 Sporozoite_P67 PF05642.6 CDI75405.1 - 0.14 9.9 15.1 0.13 10.0 10.1 1.3 1 1 0 1 1 1 0 Sporozoite P67 surface antigen DUF2981 PF11200.3 CDI75405.1 - 0.14 11.1 1.5 0.13 11.2 1.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) Plasmodium_Vir PF05795.6 CDI75405.1 - 0.34 10.0 3.2 0.41 9.8 2.2 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Rifin_STEVOR PF02009.11 CDI75405.1 - 0.35 10.4 3.8 0.53 9.8 2.7 1.3 1 0 0 1 1 1 0 Rifin/stevor family Golgin_A5 PF09787.4 CDI75405.1 - 1.1 7.7 20.1 1.3 7.4 14.0 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 NPR3 PF03666.8 CDI75405.1 - 1.2 7.6 6.1 1.3 7.4 4.2 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF1712 PF08217.6 CDI75405.1 - 1.2 7.2 4.9 1.3 7.1 3.4 1.0 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1712) Med15 PF09606.5 CDI75405.1 - 1.4 7.0 19.6 1.5 6.8 13.6 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal ATP-synt_C PF00137.16 CDI75405.1 - 1.6 8.6 9.9 0.76 9.7 1.2 2.1 2 0 0 2 2 2 0 ATP synthase subunit C DUF1675 PF07897.6 CDI75405.1 - 2.3 7.9 8.8 2.8 7.7 6.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) Guanylin PF02058.10 CDI75405.1 - 2.6 8.1 5.1 17 5.5 1.5 2.1 1 1 1 2 2 2 0 Guanylin precursor DUF2029 PF09594.5 CDI75405.1 - 3.2 7.1 14.6 6.7 6.1 10.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2029) FAM220 PF15487.1 CDI75405.1 - 5 6.4 15.9 7.8 5.7 11.0 1.3 1 0 0 1 1 1 0 FAM220 family DNA_pol_viral_N PF00242.12 CDI75405.1 - 5.8 5.8 12.2 6.3 5.7 8.4 1.2 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain DUF4551 PF15087.1 CDI75405.1 - 6.6 4.9 10.4 6.8 4.9 7.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Mcm10 PF09332.6 CDI75405.1 - 9.9 5.3 16.0 11 5.2 11.1 1.0 1 0 0 1 1 1 0 Mcm10 replication factor IFT57 PF10498.4 CDI75406.1 - 1.7e-14 53.3 0.1 6.8e-08 31.6 0.2 2.1 2 0 0 2 2 2 2 Intra-flagellar transport protein 57 KxDL PF10241.4 CDI75406.1 - 0.00043 20.1 0.6 0.072 12.9 0.4 2.6 2 0 0 2 2 2 1 Uncharacterized conserved protein Cation_efflux PF01545.16 CDI75406.1 - 0.002 17.2 0.2 0.0037 16.3 0.1 1.4 1 0 0 1 1 1 1 Cation efflux family Retrotrans_gag PF03732.12 CDI75406.1 - 0.0029 17.6 0.5 0.0079 16.2 0.0 2.0 2 0 0 2 2 2 1 Retrotransposon gag protein DUF883 PF05957.8 CDI75406.1 - 0.014 15.8 4.1 0.34 11.3 1.3 2.9 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) Mt_ATP-synt_B PF05405.9 CDI75406.1 - 0.043 13.2 1.8 0.077 12.4 1.3 1.4 1 0 0 1 1 1 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) DUF4200 PF13863.1 CDI75406.1 - 0.088 12.7 7.1 0.037 13.9 1.7 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) CCDC-167 PF15188.1 CDI75406.1 - 0.13 12.1 3.8 0.32 10.9 2.5 1.8 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 167 RRF PF01765.14 CDI75406.1 - 0.14 11.6 1.9 0.29 10.6 1.3 1.5 1 0 0 1 1 1 0 Ribosome recycling factor Spc7 PF08317.6 CDI75406.1 - 0.46 9.0 3.8 0.78 8.3 2.6 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein Hemerythrin PF01814.18 CDI75406.1 - 0.53 10.4 5.8 2.2 8.4 4.0 2.2 1 1 0 1 1 1 0 Hemerythrin HHE cation binding domain DUF445 PF04286.7 CDI75407.1 - 0.0043 16.6 39.8 0.4 10.1 24.4 2.8 1 1 1 2 2 2 2 Protein of unknown function (DUF445) RHD3 PF05879.7 CDI75407.1 - 0.038 11.9 23.3 0.045 11.6 16.2 1.1 1 0 0 1 1 1 0 Root hair defective 3 GTP-binding protein (RHD3) COMPASS-Shg1 PF05205.7 CDI75407.1 - 0.057 13.7 21.6 34 4.7 0.3 4.5 1 1 1 2 2 2 0 COMPASS (Complex proteins associated with Set1p) component shg1 YpjP PF14005.1 CDI75407.1 - 0.079 12.7 24.6 3.7 7.3 0.4 3.7 1 1 1 2 2 2 0 YpjP-like protein SecA_SW PF07516.8 CDI75407.1 - 0.25 11.0 30.6 1.1 8.9 9.5 2.2 1 1 1 2 2 2 0 SecA Wing and Scaffold domain HK97-gp10_like PF04883.7 CDI75407.1 - 0.38 11.7 13.5 1.5e+04 -4.2 9.3 4.5 1 1 0 1 1 0 0 Bacteriophage HK97-gp10, putative tail-component Penicil_amidase PF01804.13 CDI75407.1 - 0.61 9.0 4.5 0.76 8.7 3.1 1.1 1 0 0 1 1 1 0 Penicillin amidase DinB_2 PF12867.2 CDI75407.1 - 0.73 10.1 6.9 2.1e+02 2.2 4.8 3.4 1 1 0 1 1 1 0 DinB superfamily Tcp11 PF05794.8 CDI75407.1 - 1.5 7.4 20.7 2.7 6.5 14.3 1.4 1 1 0 1 1 1 0 T-complex protein 11 DUF4163 PF13739.1 CDI75407.1 - 2.2 9.0 18.7 24 5.8 0.9 3.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4163) CBFD_NFYB_HMF PF00808.18 CDI75407.1 - 2.6 8.1 41.0 35 4.5 1.8 6.0 1 1 1 2 2 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Spore_SspJ PF09575.5 CDI75407.1 - 2.8 8.2 4.3 15 5.8 0.0 3.7 1 1 2 3 3 3 0 Small spore protein J (Spore_SspJ) DUF3819 PF12842.2 CDI75407.1 - 4.1 7.0 24.2 4.1 7.0 5.2 2.9 1 1 1 2 2 2 0 Domain of unknown function (DUF3819) Neur_chan_memb PF02932.11 CDI75407.1 - 8.9 6.1 14.0 2.2e+02 1.5 9.7 2.2 1 1 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Spore_coat_CotO PF14153.1 CDI75408.1 - 0.018 14.4 14.4 0.029 13.8 10.0 1.3 1 0 0 1 1 1 0 Spore coat protein CotO DUF3449 PF11931.3 CDI75408.1 - 0.047 13.2 8.3 0.075 12.5 5.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3449) PAT1 PF09770.4 CDI75408.1 - 0.29 9.3 50.6 0.36 9.0 35.1 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SAPS PF04499.10 CDI75408.1 - 0.61 8.6 8.4 0.78 8.3 5.8 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF3792 PF12670.2 CDI75408.1 - 1.1 9.1 4.3 2.4 8.0 3.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3792) Tim54 PF11711.3 CDI75408.1 - 1.2 7.6 13.8 2 6.9 9.6 1.4 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DUF4131 PF13567.1 CDI75408.1 - 1.4 8.3 14.1 1.4e+02 1.8 9.8 2.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4131) SAGA-Tad1 PF12767.2 CDI75408.1 - 1.6 8.3 14.6 2.4 7.7 10.1 1.3 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit Med15 PF09606.5 CDI75408.1 - 3.5 5.6 57.5 4.9 5.2 39.8 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal FAM60A PF15396.1 CDI75408.1 - 4.2 7.0 10.3 6.2 6.5 7.1 1.2 1 0 0 1 1 1 0 Protein Family FAM60A Dala_Dala_lig_N PF01820.16 CDI75408.1 - 4.5 7.6 8.3 1.6e+02 2.6 5.7 2.5 2 1 0 2 2 2 0 D-ala D-ala ligase N-terminus SpoIIIAH PF12685.2 CDI75408.1 - 7.4 6.0 22.0 31 4.0 0.0 2.3 1 1 1 2 2 2 0 SpoIIIAH-like protein eIF-3_zeta PF05091.7 CDI75408.1 - 7.5 5.0 15.8 9.6 4.6 10.9 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Hid1 PF12722.2 CDI75408.1 - 9 3.8 18.5 12 3.4 12.8 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein FHA PF00498.21 CDI75409.1 - 0.0022 18.0 0.0 0.0022 18.0 0.0 2.0 2 0 0 2 2 2 1 FHA domain Rtt106 PF08512.7 CDI75411.1 - 8.5e-27 92.9 0.0 1.7e-26 92.0 0.0 1.5 1 0 0 1 1 1 1 Histone chaperone Rttp106-like SDA1 PF05285.7 CDI75411.1 - 0.39 9.9 24.5 0.54 9.4 17.0 1.2 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.7 CDI75411.1 - 0.56 8.0 27.3 0.71 7.7 18.9 1.1 1 0 0 1 1 1 0 Nop14-like family YL1 PF05764.8 CDI75411.1 - 1.4 8.4 31.3 0.075 12.6 18.1 1.4 2 0 0 2 2 2 0 YL1 nuclear protein RNase_H2-Ydr279 PF09468.5 CDI75411.1 - 2.6 7.1 10.3 3.5 6.7 7.1 1.3 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) RNA_pol_Rpc4 PF05132.9 CDI75413.1 - 3e-14 53.1 10.6 1.3e-09 38.0 0.1 3.8 4 1 0 4 4 4 2 RNA polymerase III RPC4 AP2 PF00847.15 CDI75415.1 - 2.3e-09 37.2 0.1 5.7e-09 35.9 0.1 1.7 1 0 0 1 1 1 1 AP2 domain DUF4200 PF13863.1 CDI75417.1 - 4e-19 68.7 11.8 4e-19 68.7 8.2 2.7 1 1 1 2 2 2 1 Domain of unknown function (DUF4200) Med11 PF10280.4 CDI75417.1 - 0.092 12.7 15.6 0.19 11.8 4.6 2.6 2 0 0 2 2 2 0 Mediator complex protein DUF3584 PF12128.3 CDI75418.1 - 0.0077 13.6 6.4 0.0085 13.4 4.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) Prefoldin_2 PF01920.15 CDI75418.1 - 0.01 15.6 1.5 0.01 15.6 1.0 2.0 2 1 0 2 2 2 0 Prefoldin subunit AAA_13 PF13166.1 CDI75418.1 - 0.015 13.7 0.8 0.016 13.6 0.5 1.0 1 0 0 1 1 1 0 AAA domain Caps_synth_GfcC PF06251.6 CDI75418.1 - 0.027 13.6 1.4 0.032 13.3 0.9 1.1 1 0 0 1 1 1 0 Capsule biosynthesis GfcC UBN_AB PF14075.1 CDI75418.1 - 0.029 14.0 0.7 0.034 13.8 0.5 1.2 1 0 0 1 1 1 0 Ubinuclein conserved middle domain COG2 PF06148.6 CDI75418.1 - 0.034 14.0 2.5 0.068 13.0 1.5 1.7 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 APG6 PF04111.7 CDI75418.1 - 0.039 12.9 5.0 0.045 12.8 3.5 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 Flagellin_N PF00669.15 CDI75418.1 - 0.045 13.5 1.6 0.071 12.9 1.1 1.3 1 0 0 1 1 1 0 Bacterial flagellin N-terminal helical region Vir_act_alpha_C PF10400.4 CDI75418.1 - 0.068 13.5 5.7 0.63 10.4 1.0 2.2 2 0 0 2 2 2 0 Virulence activator alpha C-term GrpE PF01025.14 CDI75418.1 - 0.07 12.6 4.9 0.087 12.3 3.4 1.2 1 1 0 1 1 1 0 GrpE HSBP1 PF06825.7 CDI75418.1 - 0.081 12.5 0.0 0.57 9.7 0.0 2.3 2 0 0 2 2 2 0 Heat shock factor binding protein 1 DUF3016 PF11454.3 CDI75418.1 - 0.1 12.1 0.3 1.7 8.1 0.2 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF3016) Atg14 PF10186.4 CDI75418.1 - 0.11 11.4 5.0 0.097 11.6 2.9 1.3 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 L31 PF09784.4 CDI75418.1 - 0.13 12.3 0.7 0.22 11.5 0.2 1.6 1 1 1 2 2 2 0 Mitochondrial ribosomal protein L31 Herpes_BLRF2 PF05812.7 CDI75418.1 - 0.15 11.9 4.1 0.55 10.0 2.8 1.8 1 1 0 1 1 1 0 Herpesvirus BLRF2 protein Paramyxo_NS_C PF02725.9 CDI75418.1 - 0.15 11.6 3.8 0.19 11.3 2.7 1.2 1 0 0 1 1 1 0 Non-structural protein C Packaging_FI PF14000.1 CDI75418.1 - 0.19 11.9 3.3 0.28 11.3 1.5 1.7 1 1 1 2 2 2 0 DNA packaging protein FI Mt_ATP-synt_B PF05405.9 CDI75418.1 - 0.22 10.9 3.2 0.29 10.5 2.2 1.1 1 0 0 1 1 1 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) GvpK PF05121.7 CDI75418.1 - 0.28 11.0 2.9 0.53 10.1 1.9 1.7 1 1 1 2 2 2 0 Gas vesicle protein K TBCA PF02970.11 CDI75418.1 - 0.33 11.0 5.5 4.2 7.5 3.9 2.1 1 1 1 2 2 2 0 Tubulin binding cofactor A HrpB7 PF09486.5 CDI75418.1 - 0.37 10.6 12.6 0.54 10.1 8.7 1.2 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) DUF1515 PF07439.6 CDI75418.1 - 0.4 10.5 1.8 0.6 9.9 1.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1515) DUF4461 PF14688.1 CDI75418.1 - 0.47 9.7 4.8 0.61 9.3 3.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4461) Spc24 PF08286.6 CDI75418.1 - 0.52 10.0 3.5 0.43 10.2 1.5 1.5 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 DUF1409 PF07197.7 CDI75418.1 - 0.68 10.0 4.4 7.3 6.7 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1409) OmpH PF03938.9 CDI75418.1 - 0.95 9.3 9.4 1.1 9.1 6.5 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) SlyX PF04102.7 CDI75418.1 - 2.2 8.7 6.7 1.7 9.0 3.4 1.8 2 0 0 2 2 2 0 SlyX Mnd1 PF03962.10 CDI75418.1 - 3.3 7.3 6.9 4.6 6.8 4.8 1.3 1 1 0 1 1 1 0 Mnd1 family Sugarporin_N PF11471.3 CDI75418.1 - 3.8 7.2 12.8 0.11 12.1 1.3 3.0 2 1 2 4 4 3 0 Maltoporin periplasmic N-terminal extension HSCB_C PF07743.8 CDI75418.1 - 4.7 7.7 11.5 2.3 8.7 4.1 2.3 1 1 0 2 2 2 0 HSCB C-terminal oligomerisation domain Striatin PF08232.7 CDI75418.1 - 4.8 7.5 8.8 39 4.5 6.1 2.4 1 1 0 1 1 1 0 Striatin family YqjK PF13997.1 CDI75418.1 - 5.7 7.1 6.7 1.8 8.7 1.7 2.3 3 0 0 3 3 3 0 YqjK-like protein FlxA PF14282.1 CDI75418.1 - 7.7 6.5 13.9 7 6.6 7.9 2.0 1 1 1 2 2 2 0 FlxA-like protein DUF1777 PF08648.7 CDI75420.1 - 8.6 6.0 94.3 15 5.2 24.9 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1777) Ribosomal_60s PF00428.14 CDI75421.1 - 0.02 15.2 6.3 0.02 15.2 4.4 2.2 2 0 0 2 2 2 0 60s Acidic ribosomal protein Asp-B-Hydro_N PF05279.6 CDI75421.1 - 1.2 8.9 50.8 0.1 12.4 29.4 2.2 2 0 0 2 2 2 0 Aspartyl beta-hydroxylase N-terminal region DUF3678 PF12435.3 CDI75421.1 - 1.3 8.6 11.0 1.3 8.6 1.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3678) Daxx PF03344.10 CDI75421.1 - 3 6.2 64.3 4.3 5.6 44.6 1.2 1 0 0 1 1 1 0 Daxx Family tRNA-synt_2b PF00587.20 CDI75422.1 - 8.5e-13 48.2 0.0 6.5e-11 42.1 0.0 2.4 1 1 1 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) Spt20 PF12090.3 CDI75422.1 - 0.0013 18.1 1.7 0.0013 18.1 1.2 2.7 2 1 0 2 2 1 1 Spt20 family TFIIA PF03153.8 CDI75422.1 - 0.0018 18.2 23.3 0.096 12.5 4.9 2.0 2 0 0 2 2 2 2 Transcription factor IIA, alpha/beta subunit zf-DHHC PF01529.15 CDI75422.1 - 0.019 14.3 0.2 0.019 14.3 0.2 2.1 2 0 0 2 2 2 0 DHHC palmitoyltransferase FAM176 PF14851.1 CDI75422.1 - 0.02 14.6 0.3 0.02 14.6 0.2 2.1 2 0 0 2 2 2 0 FAM176 family CDC45 PF02724.9 CDI75422.1 - 0.021 12.8 0.3 0.021 12.8 0.2 2.0 2 0 0 2 2 2 0 CDC45-like protein DUF2956 PF11169.3 CDI75422.1 - 0.023 14.6 30.3 0.05 13.5 7.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2956) Pex14_N PF04695.8 CDI75422.1 - 0.032 14.2 25.5 0.58 10.2 5.3 2.2 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF913 PF06025.7 CDI75422.1 - 0.04 12.6 0.3 0.04 12.6 0.2 2.1 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) Suf PF05843.9 CDI75422.1 - 0.048 13.3 22.9 0.019 14.7 3.9 2.2 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) DUF4011 PF13195.1 CDI75422.1 - 0.058 13.4 6.0 1.2 9.0 1.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4011) Spore_YhcN_YlaJ PF09580.5 CDI75422.1 - 0.087 12.9 9.5 0.14 12.2 0.3 2.2 2 0 0 2 2 2 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) Neur_chan_memb PF02932.11 CDI75422.1 - 0.17 11.7 7.6 0.34 10.7 5.3 1.4 1 1 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region FAM222A PF15258.1 CDI75422.1 - 0.23 10.6 28.6 0.28 10.3 8.3 2.1 2 0 0 2 2 2 0 Protein family of FAM222A Gti1_Pac2 PF09729.4 CDI75422.1 - 0.32 10.8 8.0 5.5 6.8 2.6 2.1 2 0 0 2 2 2 0 Gti1/Pac2 family DUF3306 PF11748.3 CDI75422.1 - 0.63 10.7 12.1 2.7 8.6 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3306) EPL1 PF10513.4 CDI75422.1 - 0.7 10.1 13.6 0.63 10.2 0.2 2.2 2 0 0 2 2 2 0 Enhancer of polycomb-like DUF4557 PF15101.1 CDI75422.1 - 0.82 9.4 37.9 0.14 12.0 9.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4557) DDHD PF02862.12 CDI75422.1 - 0.83 9.4 11.7 0.64 9.7 1.0 2.1 2 0 0 2 2 2 0 DDHD domain Dala_Dala_lig_N PF01820.16 CDI75422.1 - 0.85 9.9 7.5 8.7 6.6 0.3 2.2 2 0 0 2 2 2 0 D-ala D-ala ligase N-terminus Kei1 PF08552.6 CDI75422.1 - 1.6 8.3 7.9 6.9 6.2 0.2 2.1 2 0 0 2 2 2 0 Inositolphosphorylceramide synthase subunit Kei1 SeqA PF03925.8 CDI75422.1 - 1.8 8.2 17.7 2.3 7.8 3.0 2.1 2 0 0 2 2 2 0 SeqA protein LIM_bind PF01803.11 CDI75422.1 - 1.9 7.5 22.4 0.21 10.6 3.1 2.1 2 0 0 2 2 2 0 LIM-domain binding protein Spore_coat_CotO PF14153.1 CDI75422.1 - 3.1 7.2 23.4 0.5 9.7 2.4 2.1 2 0 0 2 2 2 0 Spore coat protein CotO DUF912 PF06024.7 CDI75422.1 - 3.5 7.7 11.0 3.9 7.5 1.7 2.3 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Peroxin-13_N PF04088.8 CDI75422.1 - 4.5 7.2 8.9 5.3 6.9 1.7 2.2 2 0 0 2 2 2 0 Peroxin 13, N-terminal region Ctr PF04145.10 CDI75422.1 - 4.6 7.2 13.1 9.4 6.2 0.9 2.2 2 0 0 2 2 2 0 Ctr copper transporter family GPCR_chapero_1 PF11904.3 CDI75422.1 - 4.9 6.2 13.3 1.8 7.6 1.0 2.1 2 0 0 2 2 2 0 GPCR-chaperone PAT1 PF09770.4 CDI75422.1 - 5.3 5.1 50.8 1.3 7.1 14.1 2.0 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 Agouti PF05039.7 CDI75422.1 - 5.5 7.3 15.3 2.5 8.5 4.5 2.3 2 0 0 2 2 2 0 Agouti protein Tim54 PF11711.3 CDI75422.1 - 5.7 5.4 10.3 1.7 7.1 0.8 2.1 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 CDK5_activator PF03261.10 CDI75422.1 - 6.6 5.9 20.0 0.16 11.2 3.4 2.1 2 0 0 2 2 2 0 Cyclin-dependent kinase 5 activator protein DUF605 PF04652.11 CDI75422.1 - 7.5 5.8 27.7 1.3 8.3 5.8 2.2 2 0 0 2 2 2 0 Vta1 like BRF1 PF07741.8 CDI75422.1 - 7.8 6.7 17.1 12 6.1 0.8 2.3 2 0 0 2 2 2 0 Brf1-like TBP-binding domain Band_3_cyto PF07565.8 CDI75422.1 - 9.1 5.7 19.9 1.8 7.9 3.4 2.2 2 0 0 2 2 2 0 Band 3 cytoplasmic domain DUF1644 PF07800.7 CDI75422.1 - 9.1 6.1 12.7 1.8 8.3 2.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1644) Folate_carrier PF01770.13 CDI75422.1 - 9.4 4.6 13.0 1.2 7.6 1.4 2.0 2 0 0 2 2 2 0 Reduced folate carrier Eaf7 PF07904.8 CDI75424.1 - 3.3 7.7 9.3 7.9 6.5 6.4 1.5 1 0 0 1 1 1 0 Chromatin modification-related protein EAF7 V_ATPase_I PF01496.14 CDI75424.1 - 6 4.5 10.0 8.4 4.1 6.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family AAA_8 PF12780.2 CDI75425.1 - 8.4e-09 34.7 1.0 0.00031 19.8 0.1 2.1 2 0 0 2 2 2 2 P-loop containing dynein motor region D4 Activator_LAG-3 PF11498.3 CDI75425.1 - 2e-07 30.1 38.8 2e-07 30.1 26.9 1.8 2 0 0 2 2 2 1 Transcriptional activator LAG-3 TMEM51 PF15345.1 CDI75425.1 - 0.0015 18.2 10.2 0.0015 18.2 7.1 2.3 2 0 0 2 2 2 1 Transmembrane protein 51 RRN3 PF05327.6 CDI75425.1 - 0.0024 16.0 9.9 0.0024 16.0 6.8 1.8 2 0 0 2 2 2 1 RNA polymerase I specific transcription initiation factor RRN3 CAF-1_p150 PF11600.3 CDI75425.1 - 0.0032 16.8 18.6 0.0032 16.8 12.9 2.4 2 0 0 2 2 2 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal FimP PF09766.4 CDI75425.1 - 0.0047 16.0 21.4 0.0047 16.0 14.8 1.6 2 0 0 2 2 2 1 Fms-interacting protein DUF572 PF04502.8 CDI75425.1 - 0.0059 15.8 30.1 0.021 14.0 3.3 2.1 2 0 0 2 2 2 2 Family of unknown function (DUF572) DUF2561 PF10812.3 CDI75425.1 - 0.0072 15.9 0.5 0.0072 15.9 0.3 1.8 2 0 0 2 2 1 1 Protein of unknown function (DUF2561) RAP1 PF07218.6 CDI75425.1 - 0.45 8.5 26.0 0.9 7.5 12.2 2.1 2 0 0 2 2 2 0 Rhoptry-associated protein 1 (RAP-1) Peptidase_S49_N PF08496.5 CDI75425.1 - 0.47 10.2 11.2 1.1 9.0 7.8 1.7 1 0 0 1 1 1 0 Peptidase family S49 N-terminal SOBP PF15279.1 CDI75425.1 - 0.95 9.7 27.0 0.89 9.8 9.7 2.2 2 0 0 2 2 2 0 Sine oculis-binding protein DDRGK PF09756.4 CDI75425.1 - 1.2 8.4 24.0 0.073 12.4 13.0 1.6 2 0 0 2 2 1 0 DDRGK domain DUF4446 PF14584.1 CDI75425.1 - 1.3 8.8 15.8 0.98 9.2 8.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) Med15 PF09606.5 CDI75425.1 - 1.5 6.9 55.0 0.078 11.1 31.4 2.1 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal PBP_sp32 PF07222.7 CDI75425.1 - 1.8 7.7 20.9 3.7 6.6 14.5 1.5 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Serinc PF03348.10 CDI75425.1 - 1.9 7.0 23.0 0.021 13.5 10.4 1.6 2 0 0 2 2 2 0 Serine incorporator (Serinc) 60KD_IMP PF02096.15 CDI75425.1 - 2.2 7.9 14.8 5.4 6.6 10.3 1.7 1 0 0 1 1 1 0 60Kd inner membrane protein SID-1_RNA_chan PF13965.1 CDI75425.1 - 2.4 6.2 10.5 4.3 5.3 7.3 1.3 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Nucleoside_tran PF01733.13 CDI75425.1 - 2.5 7.1 4.6 4.2 6.4 3.2 1.4 1 0 0 1 1 1 0 Nucleoside transporter SSP160 PF06933.6 CDI75425.1 - 3.8 5.3 26.8 2.4 6.0 2.0 2.1 2 0 0 2 2 2 0 Special lobe-specific silk protein SSP160 DUF342 PF03961.8 CDI75425.1 - 4.3 5.6 12.6 5.9 5.1 8.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) 7tm_7 PF08395.7 CDI75425.1 - 4.3 6.2 6.3 6.8 5.6 4.3 1.3 1 0 0 1 1 1 0 7tm Chemosensory receptor Peptidase_U57 PF05582.7 CDI75425.1 - 4.4 6.1 12.1 7.5 5.4 8.4 1.3 1 0 0 1 1 1 0 YabG peptidase U57 FSIP1 PF15554.1 CDI75425.1 - 4.9 5.8 36.5 0.1 11.4 12.7 3.1 3 0 0 3 3 3 0 FSIP1 family CemA PF03040.9 CDI75425.1 - 6.2 6.3 12.3 3.4 7.2 7.1 1.7 2 0 0 2 2 2 0 CemA family Apt1 PF10351.4 CDI75425.1 - 7.1 5.3 29.4 2 7.2 4.7 2.1 2 0 0 2 2 2 0 Golgi-body localisation protein domain Cas1_AcylT PF07779.7 CDI75425.1 - 8.3 4.7 5.9 17 3.6 4.0 1.6 1 1 1 2 2 2 0 10 TM Acyl Transferase domain found in Cas1p Spc7_N PF15402.1 CDI75425.1 - 8.3 4.2 39.3 0.86 7.5 13.7 2.1 2 0 0 2 2 2 0 N-terminus of kinetochore NMS complex subunit Spc7 Neur_chan_memb PF02932.11 CDI75425.1 - 8.4 6.2 19.3 11 5.7 0.6 2.2 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region RED_N PF07808.8 CDI75425.1 - 10 5.2 24.1 0.17 11.0 11.3 2.1 2 0 0 2 2 2 0 RED-like protein N-terminal region PAT1 PF09770.4 CDI75426.1 - 0.00035 18.9 83.6 0.00045 18.6 58.0 1.1 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 SAGA-Tad1 PF12767.2 CDI75426.1 - 0.076 12.6 43.9 0.12 11.9 30.4 1.3 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit Utp14 PF04615.8 CDI75426.1 - 0.19 9.8 49.6 0.25 9.4 34.4 1.0 1 0 0 1 1 1 0 Utp14 protein Macoilin PF09726.4 CDI75426.1 - 0.28 9.3 38.3 0.36 9.0 26.6 1.1 1 0 0 1 1 1 0 Transmembrane protein Asp-B-Hydro_N PF05279.6 CDI75426.1 - 1 9.1 30.9 1.5 8.6 21.4 1.3 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Draxin PF15550.1 CDI75426.1 - 4.4 6.8 30.9 5.8 6.4 21.4 1.1 1 0 0 1 1 1 0 Draxin GAGA_bind PF06217.7 CDI75426.1 - 4.6 7.1 38.5 7.8 6.3 26.7 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family DUF572 PF04502.8 CDI75426.1 - 5.8 6.0 42.6 7.7 5.6 29.6 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Myosin_head PF00063.16 CDI75430.1 - 3.2e-117 392.3 3.9 2.3e-90 303.5 0.1 3.3 3 0 0 3 3 3 3 Myosin head (motor domain) Zeta_toxin PF06414.7 CDI75430.1 - 0.016 14.2 0.1 0.032 13.3 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin Myosin_head PF00063.16 CDI75431.1 - 1.9e-133 445.9 1.5 1.1e-94 317.9 0.0 3.2 3 0 0 3 3 3 3 Myosin head (motor domain) Zeta_toxin PF06414.7 CDI75431.1 - 0.0042 16.1 0.3 0.043 12.9 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin AAA_22 PF13401.1 CDI75431.1 - 0.032 14.3 0.6 0.32 11.1 0.1 2.9 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.1 CDI75431.1 - 0.12 13.1 0.2 0.54 11.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain Fmp27_WPPW PF10359.4 CDI75432.1 - 0.045 12.1 24.2 0.054 11.9 16.8 1.0 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain DUF605 PF04652.11 CDI75432.1 - 0.075 12.4 23.1 0.091 12.1 16.0 1.1 1 0 0 1 1 1 0 Vta1 like RNA_pol_Rpc4 PF05132.9 CDI75432.1 - 0.45 10.4 24.9 0.1 12.6 4.6 2.1 2 0 0 2 2 2 0 RNA polymerase III RPC4 PAT1 PF09770.4 CDI75432.1 - 0.49 8.5 47.6 0.56 8.3 33.0 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 tRNA_synt_1c_R2 PF04557.10 CDI75432.1 - 0.51 11.0 19.3 0.3 11.8 3.0 2.1 2 0 0 2 2 2 0 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 Presenilin PF01080.12 CDI75432.1 - 1.1 8.0 12.8 1.3 7.8 8.9 1.1 1 0 0 1 1 1 0 Presenilin BTV_NS2 PF04514.7 CDI75432.1 - 2.4 6.9 18.9 2.8 6.7 13.1 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Ycf1 PF05758.7 CDI75432.1 - 2.8 5.5 24.2 3.3 5.3 16.8 1.0 1 0 0 1 1 1 0 Ycf1 DHHW PF14286.1 CDI75432.1 - 2.8 7.1 16.9 3.6 6.8 11.7 1.2 1 0 0 1 1 1 0 DHHW protein FAM60A PF15396.1 CDI75432.1 - 2.9 7.5 18.8 3.5 7.3 13.0 1.2 1 0 0 1 1 1 0 Protein Family FAM60A DUF4045 PF13254.1 CDI75432.1 - 7.1 5.7 21.5 8 5.6 14.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) SAGA-Tad1 PF12767.2 CDI75432.1 - 7.8 6.0 27.2 9.3 5.8 18.8 1.1 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit U3_snoRNA_assoc PF08297.6 CDI75432.1 - 8 6.7 23.6 1.3 9.2 5.5 2.2 2 0 0 2 2 2 0 U3 snoRNA associated Aminotran_5 PF00266.14 CDI75435.1 - 1.8e-19 69.7 0.1 3.1e-19 68.9 0.1 1.4 1 0 0 1 1 1 1 Aminotransferase class-V Na_K-ATPase PF00287.13 CDI75435.1 - 0.012 14.3 0.7 0.021 13.5 0.5 1.3 1 0 0 1 1 1 0 Sodium / potassium ATPase beta chain Peptidase_S49_N PF08496.5 CDI75435.1 - 2.2 8.0 11.4 0.32 10.7 3.3 2.3 2 0 0 2 2 2 0 Peptidase family S49 N-terminal DUF1266 PF06889.6 CDI75435.1 - 2.5 7.8 7.8 3.5 7.4 1.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1266) AUX_IAA PF02309.11 CDI75435.1 - 4.1 7.0 8.4 1.4 8.5 3.2 1.9 2 0 0 2 2 2 0 AUX/IAA family SR-25 PF10500.4 CDI75436.1 - 0.00096 18.6 15.5 0.0011 18.4 10.7 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Corona_nucleoca PF00937.13 CDI75436.1 - 0.051 12.5 22.4 0.055 12.4 15.5 1.0 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein DUF4207 PF13904.1 CDI75436.1 - 0.056 12.8 25.8 0.066 12.5 17.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4207) PAT1 PF09770.4 CDI75436.1 - 0.066 11.4 33.6 0.07 11.3 23.3 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 CAF-1_p150 PF11600.3 CDI75436.1 - 0.13 11.6 21.5 0.15 11.4 14.9 1.0 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF4048 PF13257.1 CDI75436.1 - 0.16 11.5 17.8 0.19 11.3 12.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4048) Saw1 PF11561.3 CDI75436.1 - 0.28 10.5 8.3 0.33 10.2 5.7 1.0 1 0 0 1 1 1 0 Single strand annealing-weakened 1 Spore_coat_CotO PF14153.1 CDI75436.1 - 0.29 10.5 21.5 0.31 10.4 14.9 1.0 1 0 0 1 1 1 0 Spore coat protein CotO Hormone_1 PF00103.15 CDI75436.1 - 0.57 9.4 8.8 0.62 9.3 6.1 1.1 1 0 0 1 1 1 0 Somatotropin hormone family SprA-related PF12118.3 CDI75436.1 - 0.71 9.1 33.7 0.76 9.0 23.4 1.1 1 0 0 1 1 1 0 SprA-related family RR_TM4-6 PF06459.7 CDI75436.1 - 0.78 9.5 14.1 0.86 9.4 9.8 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF4551 PF15087.1 CDI75436.1 - 1.1 7.4 17.1 1.1 7.5 11.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) NARP1 PF12569.3 CDI75436.1 - 1.3 7.7 12.0 1.3 7.6 8.3 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 APG6 PF04111.7 CDI75436.1 - 1.4 7.9 16.1 1.5 7.7 11.1 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 OmpH PF03938.9 CDI75436.1 - 1.4 8.8 30.7 1.3 8.9 21.3 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Pal1 PF08316.6 CDI75436.1 - 1.7 9.0 9.0 2.1 8.8 6.2 1.2 1 0 0 1 1 1 0 Pal1 cell morphology protein Activator_LAG-3 PF11498.3 CDI75436.1 - 2.1 6.9 47.0 2.2 6.9 32.6 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 DUF4011 PF13195.1 CDI75436.1 - 2.6 8.0 10.3 3.1 7.7 7.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4011) Suf PF05843.9 CDI75436.1 - 2.7 7.6 23.4 3.4 7.3 16.3 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF4220 PF13968.1 CDI75436.1 - 2.8 6.9 9.7 3.3 6.7 6.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4220) AUX_IAA PF02309.11 CDI75436.1 - 2.8 7.6 15.0 3.1 7.4 10.4 1.0 1 0 0 1 1 1 0 AUX/IAA family FLO_LFY PF01698.11 CDI75436.1 - 2.9 6.6 14.0 3.2 6.5 9.7 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein AAA_23 PF13476.1 CDI75436.1 - 3.8 7.7 18.1 4.7 7.4 12.5 1.1 1 0 0 1 1 1 0 AAA domain SAGA-Tad1 PF12767.2 CDI75436.1 - 3.9 7.0 24.4 4 7.0 16.9 1.0 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit Med15 PF09606.5 CDI75436.1 - 3.9 5.5 43.4 3.9 5.5 30.1 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Zip PF02535.17 CDI75436.1 - 4.7 6.1 7.6 5.3 5.9 5.3 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter CDK5_activator PF03261.10 CDI75436.1 - 4.9 6.3 17.7 5.6 6.2 12.3 1.0 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein Raftlin PF15250.1 CDI75436.1 - 5.3 5.4 16.6 5.7 5.3 11.5 1.0 1 0 0 1 1 1 0 Raftlin DUF4228 PF14009.1 CDI75436.1 - 5.4 7.1 14.8 5.8 7.0 10.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4228) GNT-I PF03071.10 CDI75436.1 - 6.3 5.2 10.9 6.9 5.1 7.6 1.0 1 0 0 1 1 1 0 GNT-I family DUF3435 PF11917.3 CDI75436.1 - 6.3 5.3 21.1 6.9 5.2 14.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3435) DUF4407 PF14362.1 CDI75436.1 - 7.3 5.4 16.0 8.3 5.2 11.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DDHD PF02862.12 CDI75436.1 - 7.5 6.2 17.9 8.7 6.0 12.4 1.1 1 0 0 1 1 1 0 DDHD domain F-protein PF00469.15 CDI75436.1 - 7.7 5.8 12.1 9.6 5.5 8.4 1.3 1 0 0 1 1 1 0 Negative factor, (F-Protein) or Nef PBP_sp32 PF07222.7 CDI75436.1 - 8.2 5.5 18.9 10 5.1 13.1 1.2 1 0 0 1 1 1 0 Proacrosin binding protein sp32 UPF0560 PF10577.4 CDI75436.1 - 8.3 4.5 22.0 9.7 4.3 15.2 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Band_3_cyto PF07565.8 CDI75436.1 - 8.6 5.7 15.5 11 5.3 10.7 1.3 1 0 0 1 1 1 0 Band 3 cytoplasmic domain DUF342 PF03961.8 CDI75436.1 - 9.1 4.5 10.4 9.8 4.4 7.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF4544 PF15077.1 CDI75436.1 - 9.4 5.6 12.8 11 5.4 8.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4544) DUF2422 PF10337.4 CDI75436.1 - 9.6 4.8 8.6 9.4 4.8 6.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2422) Spt20 PF12090.3 CDI75437.1 - 0.013 14.8 0.2 0.013 14.8 0.1 1.0 1 0 0 1 1 1 0 Spt20 family GN3L_Grn1 PF08701.6 CDI75437.1 - 3 7.8 12.6 4 7.4 8.8 1.1 1 0 0 1 1 1 0 GNL3L/Grn1 putative GTPase PT PF04886.7 CDI75437.1 - 3.5 7.0 30.5 0.76 9.1 6.5 4.6 3 1 1 4 4 4 0 PT repeat Btz PF09405.5 CDI75440.1 - 1.3e-11 44.6 1.0 1.3e-11 44.6 0.7 1.8 2 0 0 2 2 2 1 CASC3/Barentsz eIF4AIII binding TFIIA PF03153.8 CDI75441.1 - 0.0012 18.7 31.1 0.0019 18.1 21.6 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit SOBP PF15279.1 CDI75441.1 - 0.074 13.4 15.4 0.12 12.7 6.1 2.1 2 0 0 2 2 2 0 Sine oculis-binding protein Nucleo_P87 PF07267.6 CDI75441.1 - 0.53 8.9 7.4 0.78 8.3 5.1 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 CAF-1_p150 PF11600.3 CDI75441.1 - 2.1 7.7 30.9 5.5 6.3 21.4 1.6 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Bacteriocin_IIc PF10439.4 CDI75441.1 - 2.7 8.1 12.5 0.071 13.2 4.2 1.6 2 0 0 2 2 2 0 Bacteriocin class II with double-glycine leader peptide SR-25 PF10500.4 CDI75441.1 - 4 6.8 43.7 0.44 9.9 19.9 2.5 1 1 1 2 2 2 0 Nuclear RNA-splicing-associated protein Ycf1 PF05758.7 CDI75441.1 - 8.2 3.9 10.0 12 3.4 6.9 1.2 1 0 0 1 1 1 0 Ycf1 EcsB PF05975.7 CDI75442.1 - 0.00061 18.3 5.2 0.00061 18.3 3.6 1.6 1 1 0 1 1 1 1 Bacterial ABC transporter protein EcsB Hid1 PF12722.2 CDI75442.1 - 0.0088 13.7 39.6 0.011 13.5 27.5 1.1 1 0 0 1 1 1 1 High-temperature-induced dauer-formation protein FA_desaturase PF00487.19 CDI75442.1 - 0.022 14.2 0.6 0.022 14.2 0.4 2.1 2 0 0 2 2 2 0 Fatty acid desaturase PRA1 PF03208.14 CDI75442.1 - 0.28 10.5 4.9 0.7 9.2 3.4 1.7 1 1 0 1 1 1 0 PRA1 family protein Dicty_REP PF05086.7 CDI75442.1 - 0.39 8.4 30.6 0.53 7.9 21.2 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF1510 PF07423.6 CDI75442.1 - 2.5 7.4 47.0 0.021 14.1 14.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1510) YjgP_YjgQ PF03739.9 CDI75442.1 - 5.1 5.7 26.4 7.1 5.2 18.3 1.2 1 0 0 1 1 1 0 Predicted permease YjgP/YjgQ family DUF4110 PF13422.1 CDI75443.1 - 0.0038 17.0 11.6 0.0048 16.7 8.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4110) Nucleoplasmin PF03066.10 CDI75443.1 - 0.023 14.2 19.4 0.028 13.9 13.5 1.2 1 0 0 1 1 1 0 Nucleoplasmin NOA36 PF06524.7 CDI75443.1 - 0.04 13.1 11.4 0.038 13.2 7.9 1.0 1 0 0 1 1 1 0 NOA36 protein Prothymosin PF03247.9 CDI75443.1 - 0.057 13.5 30.6 0.069 13.3 21.2 1.1 1 0 0 1 1 1 0 Prothymosin/parathymosin family Mpp10 PF04006.7 CDI75443.1 - 0.096 11.0 16.5 0.098 11.0 11.4 1.0 1 0 0 1 1 1 0 Mpp10 protein Spore_coat_CotO PF14153.1 CDI75443.1 - 0.12 11.7 9.3 0.14 11.6 6.5 1.1 1 0 0 1 1 1 0 Spore coat protein CotO Nop14 PF04147.7 CDI75443.1 - 0.13 10.1 17.7 0.13 10.1 12.3 1.0 1 0 0 1 1 1 0 Nop14-like family Paf1 PF03985.8 CDI75443.1 - 0.13 10.9 16.4 0.13 10.9 11.4 1.0 1 0 0 1 1 1 0 Paf1 DUF1510 PF07423.6 CDI75443.1 - 0.2 11.0 13.2 0.19 11.0 9.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Pox_Ag35 PF03286.9 CDI75443.1 - 0.24 10.8 10.5 0.24 10.8 7.3 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Laps PF10169.4 CDI75443.1 - 0.32 11.2 7.7 0.34 11.1 5.3 1.1 1 0 0 1 1 1 0 Learning-associated protein Usp PF00582.21 CDI75443.1 - 0.33 11.1 5.1 0.33 11.1 3.6 1.1 1 0 0 1 1 1 0 Universal stress protein family Daxx PF03344.10 CDI75443.1 - 0.37 9.2 19.9 0.37 9.2 13.8 1.0 1 0 0 1 1 1 0 Daxx Family BUD22 PF09073.5 CDI75443.1 - 0.39 9.7 14.0 0.36 9.8 9.7 1.0 1 0 0 1 1 1 0 BUD22 RNA_pol_Rpc4 PF05132.9 CDI75443.1 - 0.41 10.6 6.1 0.4 10.6 4.2 1.1 1 0 0 1 1 1 0 RNA polymerase III RPC4 HSP90 PF00183.13 CDI75443.1 - 0.41 8.9 17.9 0.45 8.8 12.4 1.0 1 0 0 1 1 1 0 Hsp90 protein Sigma70_ner PF04546.8 CDI75443.1 - 0.43 10.1 17.8 0.5 9.9 12.4 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region CDC45 PF02724.9 CDI75443.1 - 0.46 8.4 12.9 0.43 8.5 8.9 1.0 1 0 0 1 1 1 0 CDC45-like protein DUF3504 PF12012.3 CDI75443.1 - 0.47 10.1 2.6 0.47 10.1 1.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3504) CobT PF06213.7 CDI75443.1 - 0.53 9.3 16.8 0.54 9.3 11.7 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT EIIBC-GUT_N PF03612.9 CDI75443.1 - 0.58 9.7 2.2 0.58 9.7 1.6 1.0 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Vfa1 PF08432.5 CDI75443.1 - 0.61 10.0 11.2 0.61 10.0 7.8 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 SspB PF04386.8 CDI75443.1 - 0.63 9.6 9.3 0.74 9.4 6.4 1.1 1 0 0 1 1 1 0 Stringent starvation protein B TRAP_alpha PF03896.11 CDI75443.1 - 0.64 8.9 13.4 0.65 8.9 9.3 1.0 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit ANAPC15 PF15243.1 CDI75443.1 - 0.73 9.9 19.9 0.86 9.7 13.8 1.2 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 15 TFIIF_alpha PF05793.7 CDI75443.1 - 0.76 8.0 17.0 0.74 8.1 11.8 1.0 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) TLP-20 PF06088.6 CDI75443.1 - 0.79 9.3 5.6 0.82 9.3 3.9 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) OAD_gamma PF04277.8 CDI75443.1 - 0.81 10.1 4.0 0.97 9.8 2.8 1.2 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain Kin17_mid PF10357.4 CDI75443.1 - 0.84 9.2 5.7 0.95 9.1 4.0 1.1 1 0 0 1 1 1 0 Domain of Kin17 curved DNA-binding protein XAP5 PF04921.9 CDI75443.1 - 0.88 9.0 8.7 0.94 8.9 6.0 1.2 1 0 0 1 1 1 0 XAP5, circadian clock regulator DUF2457 PF10446.4 CDI75443.1 - 0.9 8.1 21.0 0.96 8.1 14.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Rhabdo_ncap PF00945.13 CDI75443.1 - 0.95 7.9 6.6 1 7.8 4.6 1.0 1 0 0 1 1 1 0 Rhabdovirus nucleocapsid protein Tim54 PF11711.3 CDI75443.1 - 1.3 7.5 9.8 1.3 7.5 6.8 1.0 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 RabGAP-TBC PF00566.13 CDI75443.1 - 1.5 8.2 3.3 1.8 7.9 2.3 1.0 1 0 0 1 1 1 0 Rab-GTPase-TBC domain SMN PF06003.7 CDI75443.1 - 1.5 7.8 4.7 1.7 7.6 3.3 1.0 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) Upf2 PF04050.9 CDI75443.1 - 1.5 8.5 17.3 1.7 8.3 12.0 1.1 1 0 0 1 1 1 0 Up-frameshift suppressor 2 PPP4R2 PF09184.6 CDI75443.1 - 1.6 8.2 18.7 1.5 8.2 13.0 1.1 1 0 0 1 1 1 0 PPP4R2 SDA1 PF05285.7 CDI75443.1 - 1.6 7.9 16.8 1.6 7.9 11.6 1.0 1 0 0 1 1 1 0 SDA1 HNOBA PF07701.9 CDI75443.1 - 1.6 7.8 4.5 1.8 7.7 3.1 1.1 1 0 0 1 1 1 0 Heme NO binding associated RNA_pol_3_Rpc31 PF11705.3 CDI75443.1 - 1.7 8.5 20.8 1.8 8.4 14.5 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Nop53 PF07767.6 CDI75443.1 - 1.8 7.4 15.6 1.9 7.4 10.8 1.0 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) TraH_2 PF06871.6 CDI75443.1 - 2 7.7 4.1 2.1 7.7 2.8 1.1 1 0 0 1 1 1 0 TraH_2 YqfQ PF14181.1 CDI75443.1 - 2.1 8.3 10.6 2.4 8.1 7.3 1.1 1 0 0 1 1 1 0 YqfQ-like protein eIF-3c_N PF05470.7 CDI75443.1 - 2.2 6.2 10.0 2.3 6.2 6.9 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Myb_Cef PF11831.3 CDI75443.1 - 2.5 7.2 15.0 2.4 7.3 10.4 1.1 1 0 0 1 1 1 0 pre-mRNA splicing factor component DUF3381 PF11861.3 CDI75443.1 - 2.5 7.5 16.3 2.9 7.3 11.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) VID27 PF08553.5 CDI75443.1 - 2.7 6.0 17.4 2.7 6.1 12.0 1.0 1 0 0 1 1 1 0 VID27 cytoplasmic protein DUF2722 PF10846.3 CDI75443.1 - 3.2 6.6 6.2 3.1 6.7 4.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) DUF2146 PF10220.4 CDI75443.1 - 3.3 5.5 7.4 3.2 5.6 5.1 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2146) BTV_NS2 PF04514.7 CDI75443.1 - 3.3 6.4 13.3 3.5 6.4 9.2 1.0 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Afi1 PF07792.7 CDI75443.1 - 3.4 7.6 6.4 3.5 7.6 4.4 1.1 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Ycf1 PF05758.7 CDI75443.1 - 3.5 5.2 9.9 3.7 5.1 6.8 1.0 1 0 0 1 1 1 0 Ycf1 DDHD PF02862.12 CDI75443.1 - 4.3 7.0 5.5 4.3 7.0 3.8 1.1 1 0 0 1 1 1 0 DDHD domain Prog_receptor PF02161.10 CDI75443.1 - 4.5 5.9 9.6 4.5 5.9 6.7 1.0 1 0 0 1 1 1 0 Progesterone receptor DUF3530 PF12048.3 CDI75443.1 - 5.4 5.9 6.6 5.4 5.9 4.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) Tom22 PF04281.8 CDI75443.1 - 5.5 6.5 14.4 6.1 6.3 10.0 1.1 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 Sporozoite_P67 PF05642.6 CDI75443.1 - 6.8 4.4 10.6 7.1 4.3 7.3 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen PTRF_SDPR PF15237.1 CDI75443.1 - 6.8 6.0 10.4 6.8 6.0 7.2 1.0 1 0 0 1 1 1 0 PTRF/SDPR family CAF1A PF12253.3 CDI75443.1 - 7.7 6.7 19.9 9.1 6.4 13.8 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 subunit A RAB3GAP2_C PF14656.1 CDI75443.1 - 8 4.4 6.5 7.8 4.4 4.5 1.1 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit C-terminus DUF4337 PF14235.1 CDI75443.1 - 9.2 6.0 6.5 8.5 6.1 4.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) GOLD_2 PF13897.1 CDI75443.1 - 9.6 6.4 8.3 13 6.0 5.8 1.3 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking Med15 PF09606.5 CDI75448.1 - 0.077 11.1 26.4 0.11 10.6 18.3 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal HSP70 PF00012.15 CDI75449.1 - 2.7e-210 699.3 10.4 3e-210 699.1 7.2 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 CDI75449.1 - 1e-18 67.0 0.4 1.6e-18 66.4 0.2 1.2 1 0 0 1 1 1 1 MreB/Mbl protein DDR PF08841.5 CDI75449.1 - 0.0058 15.4 0.3 1.2 7.9 0.1 2.3 2 0 0 2 2 2 2 Diol dehydratase reactivase ATPase-like domain FGGY_C PF02782.11 CDI75449.1 - 0.007 15.9 0.0 0.015 14.9 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Hydantoinase_A PF01968.13 CDI75449.1 - 0.014 14.4 0.5 0.047 12.7 0.4 2.0 1 1 0 1 1 1 0 Hydantoinase/oxoprolinase DUF883 PF05957.8 CDI75449.1 - 5.2 7.5 7.3 5.6 7.4 1.5 3.2 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) SR-25 PF10500.4 CDI75450.1 - 3.9e-05 23.2 8.4 3.9e-05 23.2 5.8 16.4 8 4 5 13 13 13 3 Nuclear RNA-splicing-associated protein AAA_23 PF13476.1 CDI75450.1 - 0.0085 16.4 3.9 0.0085 16.4 2.7 7.7 7 2 0 7 7 7 1 AAA domain MIP-T3 PF10243.4 CDI75451.1 - 6.2e-05 21.6 71.4 6.9e-05 21.5 49.5 1.0 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 Med15 PF09606.5 CDI75451.1 - 0.15 10.2 9.3 0.19 9.9 6.4 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal RskA PF10099.4 CDI75452.1 - 0.19 11.4 14.2 0.26 11.0 9.9 1.2 1 0 0 1 1 1 0 Anti-sigma-K factor rskA Ribosomal_60s PF00428.14 CDI75453.1 - 4e-05 23.9 7.7 4e-05 23.9 5.3 8.5 3 1 5 8 8 8 1 60s Acidic ribosomal protein TFIIF_alpha PF05793.7 CDI75453.1 - 0.36 9.1 29.0 0.063 11.6 14.6 2.3 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Chorion_2 PF03964.10 CDI75454.1 - 0.029 14.9 1.0 0.031 14.7 0.7 1.3 1 0 0 1 1 1 0 Chorion family 2 BAF1_ABF1 PF04684.8 CDI75454.1 - 0.24 10.2 9.6 0.24 10.2 6.7 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Orbi_VP6 PF01516.11 CDI75454.1 - 0.48 9.4 8.0 0.49 9.4 5.5 1.0 1 0 0 1 1 1 0 Orbivirus helicase VP6 DUF1311 PF07007.7 CDI75454.1 - 0.79 9.8 7.9 1.3 9.1 5.5 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1311) CDK2AP PF09806.4 CDI75454.1 - 2.3 8.4 6.2 2.7 8.1 4.3 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein BRF1 PF07741.8 CDI75454.1 - 3.6 7.8 9.2 4.4 7.5 6.4 1.2 1 0 0 1 1 1 0 Brf1-like TBP-binding domain Pox_Ag35 PF03286.9 CDI75454.1 - 3.9 6.9 10.0 4 6.9 6.9 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DUF2890 PF11081.3 CDI75454.1 - 5.4 7.0 12.4 7.1 6.6 8.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) Pox_RNA_Pol_19 PF05320.7 CDI75454.1 - 9.1 5.9 8.0 11 5.7 5.6 1.1 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit Med15 PF09606.5 CDI75455.1 - 6e-05 21.4 171.9 0.00012 20.4 90.8 2.1 2 0 0 2 2 2 2 ARC105 or Med15 subunit of Mediator complex non-fungal Ribosomal_60s PF00428.14 CDI75455.1 - 0.003 17.9 0.0 0.003 17.9 0.0 7.0 4 2 0 4 4 4 1 60s Acidic ribosomal protein Hint_2 PF13403.1 CDI75457.1 - 2.9 7.8 9.8 0.48 10.3 3.8 1.8 2 0 0 2 2 2 0 Hint domain Peptidase_S46 PF10459.4 CDI75457.1 - 4.6 5.5 27.0 5.7 5.2 18.7 1.0 1 0 0 1 1 1 0 Peptidase S46 DUF3459 PF11941.3 CDI75457.1 - 5.8 7.1 9.3 1.7 8.8 0.2 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF3459) VWA PF00092.23 CDI75458.1 - 0.00048 19.9 0.1 2 8.0 0.0 3.1 1 1 1 3 3 3 2 von Willebrand factor type A domain IstB_IS21 PF01695.12 CDI75458.1 - 0.042 13.2 0.0 0.12 11.7 0.0 1.8 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_5 PF07728.9 CDI75460.1 - 8.7e-14 51.4 0.0 2.4e-06 27.3 0.0 2.8 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) DUF815 PF05673.8 CDI75460.1 - 0.006 15.5 0.3 0.031 13.1 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA PF00004.24 CDI75460.1 - 0.012 15.7 0.0 0.033 14.3 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Dynein_heavy PF03028.10 CDI75460.1 - 0.04 11.9 0.0 0.13 10.2 0.0 1.8 2 0 0 2 2 2 0 Dynein heavy chain and region D6 of dynein motor UPF0079 PF02367.12 CDI75460.1 - 0.11 12.1 0.0 0.24 11.0 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 ABC_tran PF00005.22 CDI75460.1 - 0.15 12.3 3.4 0.16 12.3 0.0 2.6 2 0 0 2 2 2 0 ABC transporter PXA PF02194.10 CDI75460.1 - 0.8 9.2 7.6 0.036 13.6 0.5 2.3 2 0 0 2 2 2 0 PXA domain GpcrRhopsn4 PF10192.4 CDI75460.1 - 0.93 8.6 0.2 35 3.4 0.0 2.1 2 0 0 2 2 2 0 Rhodopsin-like GPCR transmembrane domain AAA_5 PF07728.9 CDI75461.1 - 1.1e-13 51.0 0.0 1.3e-07 31.4 0.0 2.4 1 1 1 2 2 2 2 AAA domain (dynein-related subfamily) CDP-OH_P_transf PF01066.16 CDI75463.1 - 2.6e-10 40.5 2.4 2.6e-10 40.5 1.7 2.1 2 0 0 2 2 2 1 CDP-alcohol phosphatidyltransferase CAF-1_p150 PF11600.3 CDI75465.1 - 0.031 13.6 38.2 0.041 13.2 26.4 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal SR-25 PF10500.4 CDI75465.1 - 0.08 12.4 39.4 0.19 11.1 27.3 1.6 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein Spc7_N PF15402.1 CDI75465.1 - 0.15 10.0 31.7 0.18 9.7 22.0 1.0 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 DUF4603 PF15376.1 CDI75465.1 - 0.72 6.9 21.0 0.82 6.7 14.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) SprA-related PF12118.3 CDI75465.1 - 0.75 9.0 49.3 1.1 8.5 34.2 1.2 1 0 0 1 1 1 0 SprA-related family PPP4R2 PF09184.6 CDI75465.1 - 0.79 9.2 25.8 0.98 8.9 17.9 1.1 1 0 0 1 1 1 0 PPP4R2 YABBY PF04690.8 CDI75465.1 - 0.98 9.6 16.8 1.2 9.3 11.6 1.3 1 0 0 1 1 1 0 YABBY protein PAT1 PF09770.4 CDI75465.1 - 1 7.5 48.8 1.1 7.3 33.8 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TFIIA PF03153.8 CDI75465.1 - 1.1 9.1 43.6 1.2 8.9 30.2 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Corona_nucleoca PF00937.13 CDI75465.1 - 1.5 7.7 30.8 1.7 7.5 21.3 1.1 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein DUF605 PF04652.11 CDI75465.1 - 1.9 7.8 31.5 2.2 7.6 21.8 1.1 1 0 0 1 1 1 0 Vta1 like Band_3_cyto PF07565.8 CDI75465.1 - 2.6 7.4 26.1 3.6 7.0 18.1 1.3 1 0 0 1 1 1 0 Band 3 cytoplasmic domain NARP1 PF12569.3 CDI75465.1 - 3 6.4 25.3 3.6 6.2 17.6 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 N6_N4_Mtase PF01555.13 CDI75465.1 - 3.4 7.0 9.7 3.6 7.0 6.7 1.1 1 0 0 1 1 1 0 DNA methylase DUF4045 PF13254.1 CDI75465.1 - 5.2 6.2 26.8 5.9 6.0 18.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) DDRGK PF09756.4 CDI75465.1 - 5.3 6.4 34.7 6.7 6.0 24.1 1.3 1 0 0 1 1 1 0 DDRGK domain Raftlin PF15250.1 CDI75465.1 - 5.6 5.3 29.1 6.4 5.1 20.2 1.1 1 0 0 1 1 1 0 Raftlin Pal1 PF08316.6 CDI75465.1 - 5.6 7.4 15.0 7.5 7.0 10.4 1.3 1 0 0 1 1 1 0 Pal1 cell morphology protein Peptidase_S15 PF02129.13 CDI75465.1 - 6.9 6.0 16.3 7.9 5.8 11.3 1.1 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) FLO_LFY PF01698.11 CDI75465.1 - 8.1 5.1 29.0 9.4 4.9 20.1 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein DUF853 PF05872.7 CDI75465.1 - 9.9 4.3 19.1 13 3.9 13.2 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) DUF308 PF03729.8 CDI75466.1 - 0.00085 19.2 0.6 0.0019 18.1 0.4 1.6 1 0 0 1 1 1 1 Short repeat of unknown function (DUF308) Bax1-I PF01027.15 CDI75466.1 - 0.023 14.3 0.4 0.032 13.8 0.3 1.1 1 0 0 1 1 1 0 Inhibitor of apoptosis-promoting Bax1 DUF1469 PF07332.6 CDI75466.1 - 0.19 11.4 3.3 0.11 12.1 0.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1469) DUF3953 PF13129.1 CDI75466.1 - 0.32 10.6 6.4 3.1 7.5 4.4 2.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3953) DUF3592 PF12158.3 CDI75466.1 - 0.39 10.5 0.1 0.39 10.5 0.0 2.7 1 1 0 2 2 2 0 Protein of unknown function (DUF3592) DUF1418 PF07214.7 CDI75466.1 - 0.39 10.3 0.0 0.39 10.3 0.0 2.6 3 1 0 3 3 3 0 Protein of unknown function (DUF1418) Ribosomal_60s PF00428.14 CDI75466.1 - 1.5 9.2 7.2 3.1 8.2 5.0 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein TCP PF03634.8 CDI75466.1 - 2.9 8.2 19.2 9.1 6.6 10.3 2.3 2 0 0 2 2 2 0 TCP family transcription factor Draxin PF15550.1 CDI75466.1 - 4.1 6.9 14.4 6.3 6.3 10.0 1.3 1 0 0 1 1 1 0 Draxin SR-25 PF10500.4 CDI75467.1 - 0.0026 17.2 22.0 0.0026 17.2 15.2 10.0 4 3 5 9 9 9 1 Nuclear RNA-splicing-associated protein Spt20 PF12090.3 CDI75468.1 - 0.021 14.2 1.5 0.02 14.2 1.0 1.2 1 0 0 1 1 1 0 Spt20 family Baculo_PP31 PF05311.6 CDI75468.1 - 0.037 13.2 2.2 0.064 12.5 1.5 1.3 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) RAB3GAP2_N PF14655.1 CDI75468.1 - 0.24 10.3 3.9 0.26 10.2 2.7 1.3 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus vMSA PF00695.14 CDI75468.1 - 0.86 8.7 5.9 1.2 8.2 4.1 1.2 1 0 0 1 1 1 0 Major surface antigen from hepadnavirus Bud13 PF09736.4 CDI75468.1 - 4.2 7.6 15.3 0.35 11.1 6.7 1.8 2 0 0 2 2 2 0 Pre-mRNA-splicing factor of RES complex Shadoo PF14999.1 CDI75471.1 - 0.03 14.1 0.4 0.03 14.1 0.3 6.1 2 1 4 6 6 6 0 Shadow of prion protein, neuroprotective DUF1183 PF06682.7 CDI75472.1 - 0.03 13.9 4.3 0.032 13.8 3.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) UPF0139 PF03669.8 CDI75472.1 - 0.065 12.7 0.3 0.091 12.2 0.2 1.3 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0139) DUF966 PF06136.8 CDI75472.1 - 0.07 12.5 10.4 0.11 11.8 7.2 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF966) DDHD PF02862.12 CDI75472.1 - 0.15 11.7 8.3 0.18 11.5 5.8 1.0 1 0 0 1 1 1 0 DDHD domain Rtf2 PF04641.7 CDI75472.1 - 0.28 10.3 6.5 0.33 10.1 4.5 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger Toxin_49 PF15529.1 CDI75472.1 - 0.3 11.0 2.1 1.2 9.1 0.0 2.1 2 0 0 2 2 2 0 Putative toxin 49 SPX PF03105.14 CDI75472.1 - 1 9.0 9.9 1.1 9.0 6.9 1.0 1 0 0 1 1 1 0 SPX domain NUDIX_2 PF13869.1 CDI75472.1 - 1 8.6 7.3 1.1 8.5 5.0 1.0 1 0 0 1 1 1 0 Nucleotide hydrolase DUF3402 PF11882.3 CDI75472.1 - 1.7 7.5 9.6 1.9 7.4 6.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3402) G-alpha PF00503.15 CDI75472.1 - 1.9 7.0 6.9 2.3 6.8 4.8 1.2 1 0 0 1 1 1 0 G-protein alpha subunit DUF2407_C PF13373.1 CDI75472.1 - 3 7.7 6.3 0.49 10.3 0.5 1.9 1 1 1 2 2 2 0 DUF2407 C-terminal domain COG4 PF08318.7 CDI75472.1 - 3 6.5 11.7 3.7 6.2 8.1 1.1 1 0 0 1 1 1 0 COG4 transport protein Peptidase_S49_N PF08496.5 CDI75472.1 - 3.2 7.5 11.1 1.4 8.6 4.1 2.0 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Ndc1_Nup PF09531.5 CDI75472.1 - 3.7 5.8 7.6 3.9 5.7 5.3 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Afi1 PF07792.7 CDI75472.1 - 3.8 7.5 10.8 5.1 7.0 7.5 1.2 1 1 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking dsDNA_bind PF01984.15 CDI75472.1 - 4.4 7.3 38.6 1.4 8.9 5.0 2.1 2 0 0 2 2 2 0 Double-stranded DNA-binding domain Neur_chan_memb PF02932.11 CDI75472.1 - 5.2 6.8 7.0 6.5 6.5 4.9 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF4355 PF14265.1 CDI75472.1 - 5.6 6.9 24.1 6.2 6.8 3.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4355) eIF-3_zeta PF05091.7 CDI75472.1 - 6.3 5.2 14.1 7.9 4.9 9.8 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF912 PF06024.7 CDI75472.1 - 6.4 6.8 12.4 0.46 10.5 3.0 2.0 1 1 1 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Peroxin-13_N PF04088.8 CDI75472.1 - 6.8 6.6 6.6 0.78 9.6 1.1 1.8 1 1 1 2 2 2 0 Peroxin 13, N-terminal region FlaG PF03646.10 CDI75472.1 - 7.3 6.7 22.9 2.3 8.3 7.7 2.1 2 0 0 2 2 2 0 FlaG protein ARF7EP_C PF14949.1 CDI75472.1 - 7.4 7.0 10.9 12 6.3 0.1 2.1 2 0 0 2 2 2 0 ARF7 effector protein C-terminus OMPdecase PF00215.19 CDI75472.1 - 7.5 5.8 8.4 9 5.6 5.9 1.2 1 0 0 1 1 1 0 Orotidine 5'-phosphate decarboxylase / HUMPS family DUF3959 PF13105.1 CDI75472.1 - 9.1 5.5 7.0 11 5.2 4.6 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3959) Mito_fiss_reg PF05308.6 CDI75473.1 - 2.1 7.6 7.4 2.1 7.6 5.1 1.1 1 0 0 1 1 1 0 Mitochondrial fission regulator CDC27 PF09507.5 CDI75473.1 - 2.6 7.1 8.4 2.8 7.0 5.8 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 PIH1 PF08190.7 CDI75474.1 - 2.2e-10 40.5 15.9 2.2e-10 40.5 11.0 4.0 2 1 1 4 4 4 1 pre-RNA processing PIH1/Nop17 Tmemb_9 PF05434.6 CDI75475.1 - 0.00045 20.0 2.9 0.0027 17.4 0.0 2.5 2 0 0 2 2 2 1 TMEM9 Spt20 PF12090.3 CDI75475.1 - 0.3 10.3 8.2 1.1 8.5 1.0 2.2 2 0 0 2 2 2 0 Spt20 family DUF1183 PF06682.7 CDI75475.1 - 0.46 10.0 3.7 2 7.9 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1183) DUF3371 PF11851.3 CDI75475.1 - 0.95 10.1 10.8 7.6 7.2 0.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3371) Serinc PF03348.10 CDI75475.1 - 1.8 7.2 3.8 6.2 5.4 1.9 2.1 2 0 0 2 2 2 0 Serine incorporator (Serinc) RRM_1 PF00076.17 CDI75477.1 - 1.2e-22 79.2 0.0 6.4e-16 57.7 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CDI75477.1 - 6.7e-19 67.6 0.0 2.9e-11 43.1 0.0 4.1 3 1 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CDI75477.1 - 1.3e-11 44.1 0.0 0.0011 18.7 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Chromo PF00385.19 CDI75479.1 - 9e-11 41.2 0.0 2.1e-10 40.0 0.0 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain RVT_1 PF00078.22 CDI75479.1 - 2.6e-09 36.7 0.1 5e-09 35.8 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF111 PF01969.12 CDI75481.1 - 0.016 13.9 0.0 0.017 13.9 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function DUF111 FKS1_dom1 PF14288.1 CDI75484.1 - 0.29 11.0 6.3 48 3.8 0.0 4.2 4 0 0 4 4 4 0 1,3-beta-glucan synthase subunit FKS1, domain-1 Activin_recp PF01064.18 CDI75484.1 - 4.5 7.9 13.9 0.73 10.5 0.1 3.3 4 0 0 4 4 4 0 Activin types I and II receptor domain HSP70 PF00012.15 CDI75486.1 - 5.2e-176 586.1 14.6 4.3e-129 431.1 1.1 2.0 1 1 1 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.8 CDI75486.1 - 2.5e-12 46.0 2.1 2.3e-10 39.6 0.1 2.5 3 0 0 3 3 3 2 MreB/Mbl protein Hydantoinase_A PF01968.13 CDI75486.1 - 0.0021 17.2 0.1 0.0058 15.7 0.1 1.9 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase ABC2_membrane_3 PF12698.2 CDI75486.1 - 0.45 9.4 1.9 0.67 8.9 1.3 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein SAGA-Tad1 PF12767.2 CDI75487.1 - 0.0035 17.0 12.6 0.0035 17.0 8.7 5.9 3 1 0 4 4 4 1 Transcriptional regulator of RNA polII, SAGA, subunit Conotoxin PF02950.12 CDI75487.1 - 0.02 15.6 1.0 0.02 15.6 0.7 9.3 9 3 1 11 11 11 0 Conotoxin Ribosomal_60s PF00428.14 CDI75487.1 - 0.094 13.1 49.9 0.44 10.9 4.8 5.5 5 0 0 5 5 5 0 60s Acidic ribosomal protein GRP PF07172.6 CDI75487.1 - 1.5 9.3 0.0 1.5 9.3 0.0 6.4 7 1 0 7 7 7 0 Glycine rich protein family Macoilin PF09726.4 CDI75489.1 - 9.5 4.3 17.5 12 4.0 12.1 1.1 1 0 0 1 1 1 0 Transmembrane protein Bud13 PF09736.4 CDI75490.1 - 1.4e-37 129.1 5.5 1.4e-37 129.1 3.8 2.8 3 0 0 3 3 3 1 Pre-mRNA-splicing factor of RES complex AAA PF00004.24 CDI75491.1 - 5.5e-38 130.1 0.0 2.9e-36 124.5 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 CDI75491.1 - 5.6e-06 26.4 3.8 3.4e-05 23.8 0.3 3.2 1 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 CDI75491.1 - 8e-05 22.7 0.7 0.012 15.7 0.0 3.4 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.9 CDI75491.1 - 0.00051 19.7 0.2 0.0036 17.0 0.0 2.4 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 CDI75491.1 - 0.00097 19.0 0.0 0.0028 17.5 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 CDI75491.1 - 0.0026 17.4 1.9 0.06 13.1 0.0 3.2 3 0 0 3 3 3 1 Part of AAA domain AAA_17 PF13207.1 CDI75491.1 - 0.0062 17.3 1.1 0.026 15.3 0.1 2.5 2 1 0 2 2 1 1 AAA domain RuvB_N PF05496.7 CDI75491.1 - 0.0071 15.4 0.0 0.14 11.1 0.0 2.2 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus PhoH PF02562.11 CDI75491.1 - 0.011 14.9 0.5 0.021 14.0 0.0 1.6 2 0 0 2 2 2 0 PhoH-like protein IstB_IS21 PF01695.12 CDI75491.1 - 0.018 14.4 0.0 0.06 12.7 0.0 1.8 2 0 0 2 2 2 0 IstB-like ATP binding protein TIP49 PF06068.8 CDI75491.1 - 0.026 13.2 2.8 0.093 11.4 0.1 2.6 3 1 0 3 3 3 0 TIP49 C-terminus Mg_chelatase PF01078.16 CDI75491.1 - 0.028 13.6 0.0 0.069 12.2 0.0 1.7 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_25 PF13481.1 CDI75491.1 - 0.031 13.6 0.2 0.27 10.6 0.1 2.4 1 1 1 2 2 2 0 AAA domain AAA_18 PF13238.1 CDI75491.1 - 0.041 14.1 0.2 1.3 9.2 0.0 2.7 3 0 0 3 3 3 0 AAA domain DUF815 PF05673.8 CDI75491.1 - 0.052 12.4 0.0 0.27 10.1 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Zeta_toxin PF06414.7 CDI75491.1 - 0.055 12.5 0.5 0.4 9.7 0.1 2.1 2 0 0 2 2 2 0 Zeta toxin Sigma54_activ_2 PF14532.1 CDI75491.1 - 0.056 13.4 0.1 0.44 10.5 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain Sigma54_activat PF00158.21 CDI75491.1 - 0.072 12.5 0.0 0.27 10.6 0.0 2.0 1 0 0 1 1 1 0 Sigma-54 interaction domain ABC_tran PF00005.22 CDI75491.1 - 0.099 12.9 0.1 0.26 11.5 0.0 1.7 1 0 0 1 1 1 0 ABC transporter NACHT PF05729.7 CDI75491.1 - 0.12 12.0 2.1 0.36 10.4 0.0 2.5 2 1 1 3 3 3 0 NACHT domain AAA_30 PF13604.1 CDI75491.1 - 0.17 11.4 1.4 0.26 10.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 CDI75491.1 - 0.24 11.6 0.0 0.47 10.6 0.0 1.5 1 0 0 1 1 1 0 RNA helicase RRM_1 PF00076.17 CDI75493.1 - 3.5e-37 125.8 0.1 1.4e-17 63.1 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CDI75493.1 - 1.5e-33 114.5 0.0 4.4e-17 61.8 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CDI75493.1 - 1.1e-19 70.0 0.0 3.6e-09 36.3 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 CDI75493.1 - 2.4e-05 24.0 0.0 0.033 13.9 0.0 2.3 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif FixQ PF05545.6 CDI75494.1 - 0.0026 17.3 0.5 0.026 14.1 0.1 2.4 2 0 0 2 2 2 1 Cbb3-type cytochrome oxidase component FixQ DUF3450 PF11932.3 CDI75494.1 - 0.0031 16.8 6.4 0.0045 16.2 4.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) AKNA PF12443.3 CDI75494.1 - 0.014 15.4 2.2 0.021 14.8 1.5 1.4 1 0 0 1 1 1 0 AT-hook-containing transcription factor DUF418 PF04235.7 CDI75494.1 - 0.017 14.8 1.0 0.022 14.4 0.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF418) PP2C_2 PF13672.1 CDI75494.1 - 0.067 12.5 2.1 0.1 11.9 1.5 1.2 1 0 0 1 1 1 0 Protein phosphatase 2C Peptidase_S49_N PF08496.5 CDI75494.1 - 0.24 11.1 4.9 4.5 7.0 3.3 2.2 2 0 0 2 2 2 0 Peptidase family S49 N-terminal DUF342 PF03961.8 CDI75494.1 - 0.34 9.2 5.1 0.43 8.9 3.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF1993 PF09351.5 CDI75494.1 - 0.47 10.3 3.6 0.75 9.7 2.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1993) Ycf1 PF05758.7 CDI75494.1 - 0.98 7.0 4.7 1.2 6.7 3.3 1.1 1 0 0 1 1 1 0 Ycf1 DUF3373 PF11853.3 CDI75494.1 - 2 6.8 6.6 2.9 6.3 4.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) IncA PF04156.9 CDI75494.1 - 2.3 7.7 13.3 2.8 7.4 8.2 1.8 2 0 0 2 2 2 0 IncA protein RRF PF01765.14 CDI75494.1 - 5.1 6.5 12.5 10 5.5 8.6 1.4 1 0 0 1 1 1 0 Ribosome recycling factor YflT PF11181.3 CDI75497.1 - 0.1 12.7 0.4 0.18 11.9 0.3 1.4 1 0 0 1 1 1 0 Heat induced stress protein YflT Salp15 PF12115.3 CDI75497.1 - 0.31 11.2 1.5 0.95 9.6 1.1 1.8 1 0 0 1 1 1 0 Salivary protein of 15kDa inhibits CD4+ T cell activation SOBP PF15279.1 CDI75497.1 - 2.4 8.4 8.1 4.1 7.7 5.6 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein SDA1 PF05285.7 CDI75498.1 - 0.0068 15.7 42.5 0.0096 15.2 29.4 1.2 1 0 0 1 1 1 1 SDA1 LRR_9 PF14580.1 CDI75498.1 - 0.011 15.3 0.0 0.018 14.6 0.0 1.3 1 0 0 1 1 1 0 Leucine-rich repeat Suf PF05843.9 CDI75498.1 - 0.18 11.4 12.0 0.22 11.2 8.3 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) CENP-T PF15511.1 CDI75498.1 - 1.6 7.8 37.7 2.1 7.4 26.1 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T PIP5K PF01504.13 CDI75499.1 - 0.00015 21.0 0.6 0.00015 20.9 0.4 1.1 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase SseC PF04888.7 CDI75499.1 - 0.00056 19.3 23.0 0.00063 19.1 15.9 1.0 1 0 0 1 1 1 1 Secretion system effector C (SseC) like family Pex14_N PF04695.8 CDI75499.1 - 0.0015 18.5 15.1 0.0021 18.1 10.4 1.2 1 0 0 1 1 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Apc15p PF05841.6 CDI75499.1 - 0.0093 16.6 10.8 0.011 16.4 7.5 1.0 1 0 0 1 1 1 1 Apc15p protein Peptidase_S49_N PF08496.5 CDI75499.1 - 0.012 15.4 8.4 0.013 15.2 5.8 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal HD-ZIP_N PF04618.7 CDI75499.1 - 0.019 15.5 3.7 0.021 15.3 2.5 1.1 1 0 0 1 1 1 0 HD-ZIP protein N terminus Sporozoite_P67 PF05642.6 CDI75499.1 - 0.022 12.6 0.8 0.031 12.1 0.6 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen FCP1_C PF09309.5 CDI75499.1 - 0.029 13.6 7.8 0.034 13.4 5.4 1.3 1 0 0 1 1 1 0 FCP1, C-terminal ATG22 PF11700.3 CDI75499.1 - 0.037 12.5 1.7 0.041 12.3 1.2 1.1 1 0 0 1 1 1 0 Vacuole effluxer Atg22 like DUF3371 PF11851.3 CDI75499.1 - 0.043 14.4 12.4 0.044 14.4 8.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3371) TerC PF03741.11 CDI75499.1 - 0.046 13.1 0.2 0.053 12.9 0.1 1.1 1 0 0 1 1 1 0 Integral membrane protein TerC family Ndc1_Nup PF09531.5 CDI75499.1 - 0.062 11.7 7.7 0.062 11.7 5.3 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DDRGK PF09756.4 CDI75499.1 - 0.087 12.2 10.8 0.087 12.2 7.5 1.1 1 0 0 1 1 1 0 DDRGK domain Herpes_gE PF02480.11 CDI75499.1 - 0.089 11.0 1.1 0.098 10.8 0.8 1.0 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E DUF2235 PF09994.4 CDI75499.1 - 0.098 12.0 3.1 0.1 11.9 2.1 1.0 1 0 0 1 1 1 0 Uncharacterized alpha/beta hydrolase domain (DUF2235) ATE_C PF04377.10 CDI75499.1 - 0.12 12.4 2.3 0.14 12.2 1.6 1.1 1 0 0 1 1 1 0 Arginine-tRNA-protein transferase, C terminus Afi1 PF07792.7 CDI75499.1 - 0.13 12.2 8.4 0.15 12.0 5.8 1.1 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking DUF2076 PF09849.4 CDI75499.1 - 0.14 12.1 20.4 0.17 11.8 14.1 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) CPSF100_C PF13299.1 CDI75499.1 - 0.15 12.1 7.5 0.16 12.1 5.2 1.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal MRF_C2 PF13888.1 CDI75499.1 - 0.19 11.5 4.7 0.24 11.1 3.3 1.3 1 0 0 1 1 1 0 Myelin gene regulatory factor C-terminal domain 2 Gti1_Pac2 PF09729.4 CDI75499.1 - 0.19 11.5 4.8 0.19 11.5 3.3 1.1 1 0 0 1 1 1 0 Gti1/Pac2 family SAGA-Tad1 PF12767.2 CDI75499.1 - 0.2 11.3 9.6 0.19 11.3 6.6 1.1 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit Ctr PF04145.10 CDI75499.1 - 0.24 11.4 6.8 0.26 11.3 4.7 1.1 1 0 0 1 1 1 0 Ctr copper transporter family Med15 PF09606.5 CDI75499.1 - 0.3 9.2 39.3 0.33 9.0 27.2 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Glt_symporter PF03616.9 CDI75499.1 - 0.3 9.5 4.0 0.35 9.3 2.8 1.2 1 0 0 1 1 1 0 Sodium/glutamate symporter SLD3 PF08639.5 CDI75499.1 - 0.34 9.4 9.9 0.31 9.6 6.9 1.1 1 0 0 1 1 1 0 DNA replication regulator SLD3 Bud13 PF09736.4 CDI75499.1 - 0.35 11.1 11.6 0.34 11.1 8.1 1.2 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex DUF912 PF06024.7 CDI75499.1 - 0.35 10.9 10.3 0.35 10.9 6.6 1.4 1 1 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) FAM176 PF14851.1 CDI75499.1 - 0.37 10.4 5.2 0.43 10.2 3.6 1.1 1 0 0 1 1 1 0 FAM176 family Rot1 PF10681.4 CDI75499.1 - 0.37 10.1 5.7 0.44 9.8 3.9 1.1 1 0 0 1 1 1 0 Chaperone for protein-folding within the ER, fungal DUF4647 PF15504.1 CDI75499.1 - 0.39 9.5 12.2 0.37 9.5 8.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4647) DDHD PF02862.12 CDI75499.1 - 0.39 10.4 6.5 0.38 10.5 4.5 1.1 1 0 0 1 1 1 0 DDHD domain PAT1 PF09770.4 CDI75499.1 - 0.44 8.7 26.1 0.41 8.8 18.1 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Pex16 PF08610.5 CDI75499.1 - 0.48 9.3 6.6 0.45 9.4 4.5 1.1 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) Suf PF05843.9 CDI75499.1 - 0.48 10.1 15.6 0.5 10.0 10.8 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) BRF1 PF07741.8 CDI75499.1 - 0.56 10.4 18.1 0.89 9.8 12.5 1.4 1 1 0 1 1 1 0 Brf1-like TBP-binding domain AAA_28 PF13521.1 CDI75499.1 - 0.56 10.1 6.3 0.65 9.9 4.3 1.1 1 0 0 1 1 1 0 AAA domain Serinc PF03348.10 CDI75499.1 - 0.69 8.5 8.0 0.73 8.4 5.6 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) FAM60A PF15396.1 CDI75499.1 - 0.7 9.6 6.5 0.71 9.5 4.5 1.1 1 0 0 1 1 1 0 Protein Family FAM60A Band_3_cyto PF07565.8 CDI75499.1 - 0.74 9.2 9.7 0.7 9.3 6.7 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain MSP1_C PF07462.6 CDI75499.1 - 0.75 8.1 4.5 0.85 7.9 3.1 1.2 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus OATP PF03137.15 CDI75499.1 - 0.79 7.6 8.7 0.78 7.7 6.0 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Abhydrolase_4 PF08386.5 CDI75499.1 - 0.83 9.5 6.0 1.2 9.0 4.1 1.4 1 1 0 1 1 1 0 TAP-like protein WES_acyltransf PF03007.11 CDI75499.1 - 0.85 9.1 9.6 0.87 9.0 6.6 1.0 1 0 0 1 1 1 0 Wax ester synthase-like Acyl-CoA acyltransferase domain DUF1980 PF09323.5 CDI75499.1 - 0.85 9.3 6.5 0.86 9.3 4.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) DUF966 PF06136.8 CDI75499.1 - 0.97 8.7 9.9 1 8.7 6.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Neur_chan_memb PF02932.11 CDI75499.1 - 1 9.2 3.7 0.96 9.2 2.6 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Hist_deacetyl PF00850.14 CDI75499.1 - 1.1 8.5 5.4 1.2 8.3 3.7 1.1 1 0 0 1 1 1 0 Histone deacetylase domain Sec62 PF03839.11 CDI75499.1 - 1.2 8.4 4.9 1.3 8.4 3.4 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 Hid1 PF12722.2 CDI75499.1 - 1.3 6.6 9.5 1.2 6.7 6.6 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Mucin PF01456.12 CDI75499.1 - 1.4 8.7 12.1 1.8 8.3 8.4 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein ABC2_membrane_2 PF12679.2 CDI75499.1 - 1.4 7.7 5.4 1.9 7.2 3.7 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF2232 PF09991.4 CDI75499.1 - 1.4 7.8 7.5 1.6 7.6 5.2 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) Anoctamin PF04547.7 CDI75499.1 - 1.4 7.4 4.9 1.3 7.6 3.4 1.1 1 0 0 1 1 1 0 Calcium-activated chloride channel eIF-3_zeta PF05091.7 CDI75499.1 - 1.5 7.3 12.3 1.3 7.5 8.6 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Glyco_transf_15 PF01793.11 CDI75499.1 - 1.6 7.6 8.5 1.5 7.7 5.9 1.1 1 0 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase Peptidase_C58 PF03543.9 CDI75499.1 - 1.7 8.1 19.5 1.8 8.0 13.5 1.0 1 0 0 1 1 1 0 Yersinia/Haemophilus virulence surface antigen Baculo_PP31 PF05311.6 CDI75499.1 - 1.7 7.8 9.7 1.6 7.8 6.7 1.2 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) DUF4192 PF13830.1 CDI75499.1 - 1.9 8.0 14.3 2.2 7.8 9.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4192) Ycf1 PF05758.7 CDI75499.1 - 2 6.0 8.4 1.7 6.2 5.8 1.0 1 0 0 1 1 1 0 Ycf1 Lin-8 PF03353.10 CDI75499.1 - 2.1 7.5 13.0 2.3 7.4 9.0 1.0 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Otopetrin PF03189.8 CDI75499.1 - 2.2 7.1 7.2 2.2 7.2 5.0 1.0 1 0 0 1 1 1 0 Otopetrin G-alpha PF00503.15 CDI75499.1 - 2.3 6.8 9.1 2.8 6.5 6.3 1.1 1 0 0 1 1 1 0 G-protein alpha subunit DUF3292 PF11696.3 CDI75499.1 - 2.7 5.7 7.6 2.9 5.6 5.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) Peptidase_S64 PF08192.6 CDI75499.1 - 2.7 6.2 8.5 2.8 6.1 5.9 1.0 1 0 0 1 1 1 0 Peptidase family S64 Rtf2 PF04641.7 CDI75499.1 - 2.7 7.1 12.2 2.7 7.1 8.5 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger Rpp20 PF12328.3 CDI75499.1 - 3 7.5 8.5 3.1 7.4 5.9 1.2 1 0 0 1 1 1 0 Rpp20 subunit of nuclear RNase MRP and P AUX_IAA PF02309.11 CDI75499.1 - 3.5 7.3 8.9 3.5 7.3 6.2 1.1 1 0 0 1 1 1 0 AUX/IAA family zf-DHHC PF01529.15 CDI75499.1 - 4 6.8 6.5 4.7 6.5 4.5 1.2 1 0 0 1 1 1 0 DHHC palmitoyltransferase UPF0560 PF10577.4 CDI75499.1 - 4.1 5.5 16.2 4 5.5 11.3 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 PIH1 PF08190.7 CDI75499.1 - 4.3 6.6 15.7 4.6 6.5 10.9 1.0 1 0 0 1 1 1 0 pre-RNA processing PIH1/Nop17 DUF3347 PF11827.3 CDI75499.1 - 4.6 7.1 14.5 5.3 7.0 10.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3347) GlnE PF03710.10 CDI75499.1 - 6.2 5.9 14.1 6.7 5.8 9.8 1.0 1 0 0 1 1 1 0 Glutamate-ammonia ligase adenylyltransferase DHHW PF14286.1 CDI75499.1 - 6.3 6.0 8.6 6.3 5.9 6.0 1.1 1 0 0 1 1 1 0 DHHW protein WASH-7_C PF14746.1 CDI75499.1 - 6.5 6.3 10.0 7.4 6.1 6.9 1.2 1 0 0 1 1 1 0 WASH complex subunit 7, C-terminal Nop53 PF07767.6 CDI75499.1 - 8 5.3 17.9 8.3 5.2 12.4 1.0 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) NMDAR2_C PF10565.4 CDI75499.1 - 8.5 4.9 12.7 8.2 4.9 8.8 1.1 1 0 0 1 1 1 0 N-methyl D-aspartate receptor 2B3 C-terminus Paramyxo_ncap PF00973.14 CDI75499.1 - 9.8 4.7 8.2 11 4.6 5.7 1.0 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein CDC45 PF02724.9 CDI75500.1 - 0.022 12.8 28.8 0.025 12.6 19.9 1.0 1 0 0 1 1 1 0 CDC45-like protein SAPS PF04499.10 CDI75500.1 - 0.31 9.6 26.5 0.34 9.4 18.4 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein FAM60A PF15396.1 CDI75500.1 - 3.1 7.4 30.9 5.3 6.7 21.4 1.4 1 0 0 1 1 1 0 Protein Family FAM60A DUF4045 PF13254.1 CDI75500.1 - 7.9 5.6 32.8 9.4 5.3 22.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) VID27 PF08553.5 CDI75500.1 - 8.1 4.5 29.5 9.3 4.3 20.4 1.0 1 0 0 1 1 1 0 VID27 cytoplasmic protein SR-25 PF10500.4 CDI75502.1 - 0.0033 16.9 31.2 0.0033 16.9 21.6 18.6 7 6 9 17 17 17 1 Nuclear RNA-splicing-associated protein DUF3042 PF11240.3 CDI75504.1 - 0.064 13.0 1.2 0.11 12.3 0.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3042) Med15 PF09606.5 CDI75504.1 - 0.69 8.0 146.9 0.87 7.7 101.9 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal CAF-1_p150 PF11600.3 CDI75504.1 - 1.5 8.1 63.2 2.5 7.4 43.8 1.3 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal PAT1 PF09770.4 CDI75504.1 - 1.7 6.7 119.0 2 6.5 82.5 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Utp14 PF04615.8 CDI75504.1 - 2.3 6.2 64.2 2.9 5.9 44.5 1.0 1 0 0 1 1 1 0 Utp14 protein DUF3916 PF13079.1 CDI75505.1 - 0.0032 17.1 0.1 0.0063 16.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3916) Glyco_transf_17 PF04724.8 CDI75506.1 - 5.7e-14 51.8 5.1 1.3e-13 50.6 3.5 1.6 1 1 0 1 1 1 1 Glycosyltransferase family 17 Esterase PF00756.15 CDI75506.1 - 0.02 14.3 0.8 0.041 13.3 0.5 1.4 1 0 0 1 1 1 0 Putative esterase Rota_VP2 PF05087.7 CDI75506.1 - 5.5 4.7 4.5 8 4.2 3.2 1.1 1 0 0 1 1 1 0 Rotavirus VP2 protein Epimerase PF01370.16 CDI75507.1 - 5.2e-41 140.6 0.0 7.2e-41 140.1 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 CDI75507.1 - 3.7e-05 22.7 0.0 5.7e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 CDI75507.1 - 0.016 14.1 0.3 0.041 12.7 0.0 1.6 1 1 1 2 2 2 0 Polysaccharide biosynthesis protein Lebercilin PF15619.1 CDI75509.1 - 1 8.7 30.7 1 8.7 0.3 3.8 3 1 1 4 4 4 0 Ciliary protein causing Leber congenital amaurosis disease Ax_dynein_light PF10211.4 CDI75509.1 - 1.9 8.3 24.6 0.17 11.7 9.5 3.1 3 0 0 3 3 3 0 Axonemal dynein light chain RD3 PF14473.1 CDI75509.1 - 2.1 7.8 11.5 0.69 9.3 4.7 2.4 2 0 0 2 2 2 0 RD3 protein DUF4064 PF13273.1 CDI75510.1 - 0.099 12.7 1.9 20 5.3 0.2 3.7 3 0 0 3 3 3 0 Protein of unknown function (DUF4064) DUF2899 PF11449.3 CDI75510.1 - 0.3 10.2 13.7 0.47 9.5 3.9 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2899) Tetraspannin PF00335.15 CDI75510.1 - 8.7 5.5 14.9 12 5.1 2.6 4.2 4 1 0 4 4 4 0 Tetraspanin family DUF169 PF02596.10 CDI75511.1 - 0.00021 20.7 3.2 0.24 10.7 0.1 2.5 2 0 0 2 2 2 2 Uncharacterised ArCR, COG2043 Activator_LAG-3 PF11498.3 CDI75512.1 - 6.4e-06 25.1 18.3 9.2e-06 24.6 12.7 1.2 1 0 0 1 1 1 1 Transcriptional activator LAG-3 Med15 PF09606.5 CDI75512.1 - 0.03 12.5 30.0 0.042 12.0 20.8 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal PAT1 PF09770.4 CDI75512.1 - 0.46 8.6 25.9 0.56 8.3 17.9 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Asp-B-Hydro_N PF05279.6 CDI75512.1 - 0.52 10.1 17.0 0.86 9.3 11.8 1.4 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Parvo_coat PF00740.13 CDI75512.1 - 1.1 8.0 15.1 1.4 7.8 10.4 1.1 1 0 0 1 1 1 0 Parvovirus coat protein VP2 Ycf1 PF05758.7 CDI75512.1 - 1.3 6.6 15.1 1.9 6.0 10.4 1.2 1 0 0 1 1 1 0 Ycf1 DUF2052 PF09747.4 CDI75512.1 - 2.3 8.0 23.6 0.5 10.2 12.7 2.1 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) CDC45 PF02724.9 CDI75512.1 - 3.3 5.6 25.1 1.1 7.2 13.1 2.0 2 0 0 2 2 2 0 CDC45-like protein FAM60A PF15396.1 CDI75512.1 - 3.8 7.2 22.7 1 9.0 10.4 2.1 2 0 0 2 2 2 0 Protein Family FAM60A Plasmodium_Vir PF05795.6 CDI75512.1 - 3.9 6.5 15.3 3.3 6.8 7.3 2.0 2 0 0 2 2 2 0 Plasmodium vivax Vir protein CKAP2_C PF15297.1 CDI75512.1 - 4 6.1 18.9 17 4.0 12.6 1.9 2 0 0 2 2 2 0 Cytoskeleton-associated protein 2 C-terminus RP-C_C PF11800.3 CDI75512.1 - 5.4 6.6 26.6 11 5.6 0.1 2.4 1 1 1 2 2 2 0 Replication protein C C-terminal region LMBR1 PF04791.11 CDI75512.1 - 7.5 5.0 8.0 11 4.5 5.6 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Zip PF02535.17 CDI75514.1 - 0.024 13.6 9.9 0.035 13.1 6.9 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter eIF-3_zeta PF05091.7 CDI75514.1 - 0.089 11.3 22.1 0.11 11.0 15.3 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Herpes_DNAp_acc PF04929.7 CDI75514.1 - 3.6 6.4 15.2 4.7 6.0 10.6 1.4 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Herpes_UL87 PF03043.9 CDI75514.1 - 3.7 5.8 10.2 3.9 5.7 7.0 1.1 1 0 0 1 1 1 0 Herpesvirus UL87 family PAT1 PF09770.4 CDI75514.1 - 6.6 4.8 63.4 7.6 4.6 43.9 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Hid1 PF12722.2 CDI75514.1 - 6.7 4.2 22.9 8.7 3.8 15.8 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein PCEMA1 PF07418.6 CDI75514.1 - 6.8 5.9 11.1 9.8 5.4 7.7 1.3 1 0 0 1 1 1 0 Acidic phosphoprotein precursor PCEMA1 UCH PF00443.24 CDI75515.1 - 1.2e-21 77.0 0.0 1.4e-20 73.5 0.0 2.4 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase N6_N4_Mtase PF01555.13 CDI75515.1 - 0.12 11.8 2.1 4 6.8 0.3 2.3 2 0 0 2 2 2 0 DNA methylase zf-DHHC PF01529.15 CDI75515.1 - 0.57 9.5 7.7 9.7 5.5 0.0 3.1 4 0 0 4 4 4 0 DHHC palmitoyltransferase Spt20 PF12090.3 CDI75515.1 - 4.1 6.7 28.8 3.6 6.9 4.5 3.5 3 0 0 3 3 3 0 Spt20 family Med15 PF09606.5 CDI75516.1 - 0.00011 20.6 42.1 0.00011 20.5 29.2 1.2 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal IncA PF04156.9 CDI75516.1 - 0.0018 17.8 19.8 0.0022 17.5 13.7 1.3 1 0 0 1 1 1 1 IncA protein DUF4367 PF14285.1 CDI75516.1 - 0.015 14.6 13.7 0.025 13.8 9.5 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4367) PAT1 PF09770.4 CDI75516.1 - 0.02 13.1 37.3 0.02 13.1 25.8 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Cwf_Cwc_15 PF04889.7 CDI75516.1 - 0.035 13.8 19.1 0.042 13.5 13.2 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF1176 PF06674.6 CDI75516.1 - 0.038 13.0 14.3 0.045 12.8 9.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1176) GBP_C PF02841.9 CDI75516.1 - 0.047 12.8 27.7 0.059 12.5 19.2 1.2 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain Peptidase_C58 PF03543.9 CDI75516.1 - 0.052 13.0 19.3 0.064 12.7 13.4 1.2 1 0 0 1 1 1 0 Yersinia/Haemophilus virulence surface antigen DUF4175 PF13779.1 CDI75516.1 - 0.071 10.8 36.6 0.085 10.5 25.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) DUF2235 PF09994.4 CDI75516.1 - 0.14 11.5 6.0 0.15 11.3 4.2 1.2 1 0 0 1 1 1 0 Uncharacterized alpha/beta hydrolase domain (DUF2235) DDRGK PF09756.4 CDI75516.1 - 0.14 11.5 20.5 0.18 11.2 14.2 1.2 1 0 0 1 1 1 0 DDRGK domain Gag_spuma PF03276.9 CDI75516.1 - 0.24 9.6 24.5 0.25 9.6 17.0 1.2 1 0 0 1 1 1 0 Spumavirus gag protein Asp-B-Hydro_N PF05279.6 CDI75516.1 - 0.29 10.9 12.2 0.31 10.8 8.5 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region eIF-3_zeta PF05091.7 CDI75516.1 - 0.31 9.6 21.3 0.34 9.4 14.8 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Peptidase_S15 PF02129.13 CDI75516.1 - 0.34 10.2 10.1 0.39 10.0 7.0 1.1 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) CTNNB1_binding PF08347.6 CDI75516.1 - 0.51 10.5 14.6 0.61 10.3 10.1 1.1 1 0 0 1 1 1 0 N-terminal CTNNB1 binding DUF2228 PF10228.4 CDI75516.1 - 0.64 9.5 13.1 0.83 9.1 9.1 1.1 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2228) Arena_RNA_pol PF06317.6 CDI75516.1 - 0.68 6.4 19.3 0.8 6.2 13.4 1.0 1 0 0 1 1 1 0 Arenavirus RNA polymerase AAA_11 PF13086.1 CDI75516.1 - 1 8.8 24.6 0.97 8.9 16.7 1.2 1 1 0 1 1 1 0 AAA domain DUF3492 PF11997.3 CDI75516.1 - 1.3 8.4 9.3 1.3 8.5 6.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3492) DUF572 PF04502.8 CDI75516.1 - 1.4 8.0 26.9 1.6 7.8 18.6 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF3617 PF12276.3 CDI75516.1 - 1.7 8.0 32.6 3.4 7.1 22.6 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3617) 5_nucleotid PF05761.9 CDI75516.1 - 1.7 7.0 14.8 1.9 6.8 10.2 1.1 1 0 0 1 1 1 0 5' nucleotidase family FliP PF00813.15 CDI75516.1 - 1.8 8.2 9.4 2 8.0 6.5 1.3 1 0 0 1 1 1 0 FliP family Cellulose_synt PF03552.9 CDI75516.1 - 2.2 6.5 14.1 2.4 6.3 9.8 1.0 1 0 0 1 1 1 0 Cellulose synthase VIT1 PF01988.14 CDI75516.1 - 2.2 7.7 9.9 2.5 7.5 6.8 1.1 1 0 0 1 1 1 0 VIT family DUF3801 PF12687.2 CDI75516.1 - 2.6 7.5 21.8 3.5 7.1 15.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3801) PP2C_2 PF13672.1 CDI75516.1 - 2.6 7.3 13.1 3.1 7.1 9.1 1.3 1 0 0 1 1 1 0 Protein phosphatase 2C CoA_transf_3 PF02515.12 CDI75516.1 - 2.7 7.1 10.5 3.1 6.9 7.3 1.1 1 0 0 1 1 1 0 CoA-transferase family III Exonuc_VII_L PF02601.10 CDI75516.1 - 3.2 6.8 26.7 3.6 6.6 18.5 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit ARGLU PF15346.1 CDI75516.1 - 3.9 7.2 31.8 5.6 6.7 22.1 1.2 1 0 0 1 1 1 0 Arginine and glutamate-rich 1 DUF106 PF01956.11 CDI75516.1 - 3.9 6.9 23.6 4.5 6.7 16.2 1.3 1 1 0 1 1 1 0 Integral membrane protein DUF106 DUF3450 PF11932.3 CDI75516.1 - 4.3 6.5 36.8 6.1 6.0 25.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Ribosomal_60s PF00428.14 CDI75516.1 - 5 7.5 16.9 9.5 6.7 11.7 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein DUF4220 PF13968.1 CDI75516.1 - 5.1 6.0 11.3 5.6 5.9 7.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4220) MAT1 PF06391.8 CDI75516.1 - 5.2 6.6 29.3 7.4 6.1 20.3 1.3 1 0 0 1 1 1 0 CDK-activating kinase assembly factor MAT1 DUF2217 PF10265.4 CDI75516.1 - 5.5 5.6 23.6 6.4 5.4 16.4 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) DUF2265 PF10023.4 CDI75516.1 - 6.1 5.8 18.7 7.1 5.6 13.0 1.1 1 0 0 1 1 1 0 Predicted aminopeptidase (DUF2265) Mem_trans PF03547.13 CDI75516.1 - 6.3 4.9 18.9 7.4 4.7 13.1 1.1 1 0 0 1 1 1 0 Membrane transport protein GNT-I PF03071.10 CDI75516.1 - 6.3 5.2 16.2 7.1 5.0 11.3 1.1 1 0 0 1 1 1 0 GNT-I family Endonuc_Holl PF10107.4 CDI75516.1 - 6.5 6.4 20.9 11 5.7 14.5 1.4 1 0 0 1 1 1 0 Endonuclease related to archaeal Holliday junction resolvase ZYG-11_interact PF05884.7 CDI75516.1 - 6.5 5.7 18.1 7.1 5.6 12.6 1.1 1 0 0 1 1 1 0 Interactor of ZYG-11 Pex16 PF08610.5 CDI75516.1 - 6.7 5.6 19.3 8.3 5.3 13.3 1.1 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) 7TM_transglut PF14402.1 CDI75516.1 - 7.6 5.3 13.4 8.6 5.1 9.3 1.0 1 0 0 1 1 1 0 7 transmembrane helices usually fused to an inactive transglutaminase Lin-8 PF03353.10 CDI75516.1 - 9.4 5.4 24.1 13 4.9 16.7 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist PAT1 PF09770.4 CDI75517.1 - 0.92 7.6 146.5 1 7.5 101.5 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 LMBR1 PF04791.11 CDI75518.1 - 4.7 5.6 10.2 4.7 5.6 2.5 2.7 1 1 0 2 2 2 0 LMBR1-like membrane protein RLL PF10036.4 CDI75518.1 - 7.8 5.8 39.7 0.018 14.5 6.5 3.5 2 1 1 3 3 3 0 Putative carnitine deficiency-associated protein CAF-1_p150 PF11600.3 CDI75519.1 - 0.0054 16.1 29.6 0.0054 16.1 20.5 5.1 3 1 1 4 4 4 2 Chromatin assembly factor 1 complex p150 subunit, N-terminal SPARC_Ca_bdg PF10591.4 CDI75520.1 - 0.032 14.2 0.3 0.032 14.2 0.2 1.4 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region SH3BP5 PF05276.9 CDI75520.1 - 0.14 11.4 1.0 0.15 11.3 0.1 1.4 2 0 0 2 2 2 0 SH3 domain-binding protein 5 (SH3BP5) IncA PF04156.9 CDI75520.1 - 1.3 8.6 3.5 3.5 7.1 2.4 1.6 1 1 0 1 1 1 0 IncA protein IncA PF04156.9 CDI75521.1 - 0.0029 17.2 12.2 0.0029 17.2 8.4 4.4 2 1 3 5 5 5 1 IncA protein Pox_A_type_inc PF04508.7 CDI75521.1 - 0.33 10.8 0.0 0.33 10.8 0.0 7.4 9 1 0 9 9 9 0 Viral A-type inclusion protein repeat Reo_sigmaC PF04582.7 CDI75521.1 - 0.81 8.8 10.0 0.47 9.5 1.5 2.5 2 1 1 3 3 3 0 Reovirus sigma C capsid protein NPV_P10 PF05531.7 CDI75521.1 - 7.2 6.9 17.6 0.66 10.2 1.6 5.2 3 2 1 5 5 5 0 Nucleopolyhedrovirus P10 protein Ribophorin_I PF04597.9 CDI75522.1 - 1.5e-58 198.3 0.0 3.4e-58 197.2 0.0 1.5 2 0 0 2 2 2 1 Ribophorin I SET PF00856.23 CDI75523.1 - 2.5e-06 27.8 0.0 6e-06 26.6 0.0 1.6 1 0 0 1 1 1 1 SET domain Daxx PF03344.10 CDI75524.1 - 0.69 8.3 14.6 0.69 8.3 10.1 1.1 1 0 0 1 1 1 0 Daxx Family DUF1510 PF07423.6 CDI75524.1 - 1.3 8.3 8.6 1.9 7.8 6.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) TT_ORF2 PF02957.10 CDI75524.1 - 4.6 7.9 7.4 9.8 6.9 5.1 1.6 1 0 0 1 1 1 0 TT viral ORF2 SOBP PF15279.1 CDI75525.1 - 6e-05 23.5 44.3 0.00079 19.8 16.6 2.1 2 0 0 2 2 2 2 Sine oculis-binding protein Claudin_2 PF13903.1 CDI75525.1 - 0.0013 18.4 3.0 0.0013 18.4 2.1 5.0 2 1 3 5 5 5 1 PMP-22/EMP/MP20/Claudin tight junction AAA_23 PF13476.1 CDI75525.1 - 0.0021 18.4 16.2 0.17 12.1 0.3 2.3 2 0 0 2 2 2 2 AAA domain SGT1 PF07093.6 CDI75525.1 - 0.0041 15.5 0.7 0.0041 15.5 0.5 3.0 3 0 0 3 3 3 1 SGT1 protein TFIIA PF03153.8 CDI75525.1 - 0.0055 16.6 17.6 0.0055 16.6 12.2 2.6 2 1 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit Cwf_Cwc_15 PF04889.7 CDI75525.1 - 0.12 12.0 35.0 0.27 10.9 1.0 4.1 4 0 0 4 4 4 0 Cwf15/Cwc15 cell cycle control protein EphA2_TM PF14575.1 CDI75525.1 - 8.6 6.8 19.7 13 6.2 1.6 4.2 4 0 0 4 4 4 0 Ephrin type-A receptor 2 transmembrane domain AF1Q PF15017.1 CDI75526.1 - 0.064 13.1 0.0 0.099 12.5 0.0 1.2 1 0 0 1 1 1 0 Drug resistance and apoptosis regulator MLANA PF14991.1 CDI75526.1 - 0.13 12.2 0.1 0.21 11.5 0.1 1.4 1 1 0 1 1 1 0 Protein melan-A Spc7_N PF15402.1 CDI75526.1 - 0.16 9.9 2.3 0.2 9.6 1.6 1.1 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 Alpha-mann_mid PF09261.6 CDI75526.1 - 0.17 12.0 2.8 0.26 11.4 1.7 1.5 1 1 0 1 1 1 0 Alpha mannosidase, middle domain E_Pc_C PF06752.7 CDI75526.1 - 2.5 7.5 30.0 0.027 13.9 13.7 2.2 2 0 0 2 2 2 0 Enhancer of Polycomb C-terminus OmpH PF03938.9 CDI75527.1 - 1.7e-07 31.3 0.1 3.1e-07 30.4 0.1 1.3 1 1 0 1 1 1 1 Outer membrane protein (OmpH-like) Zip PF02535.17 CDI75527.1 - 0.0011 17.9 6.8 0.0015 17.6 4.7 1.2 1 0 0 1 1 1 1 ZIP Zinc transporter Raftlin PF15250.1 CDI75527.1 - 0.42 9.0 11.1 0.012 14.1 3.6 1.4 2 0 0 2 2 2 0 Raftlin PAT1 PF09770.4 CDI75527.1 - 0.44 8.7 29.2 0.2 9.8 15.1 2.1 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 DUF3306 PF11748.3 CDI75527.1 - 3.8 8.1 10.8 5.3 7.7 5.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3306) WD40 PF00400.27 CDI75528.1 - 3.3e-06 26.7 0.6 0.064 13.1 0.0 3.1 3 0 0 3 3 3 2 WD domain, G-beta repeat Ycf1 PF05758.7 CDI75528.1 - 0.00091 17.0 12.1 0.00091 17.0 8.4 3.0 3 0 0 3 3 3 1 Ycf1 Daxx PF03344.10 CDI75528.1 - 0.0015 17.1 17.2 0.0015 17.1 11.9 3.2 4 0 0 4 4 4 1 Daxx Family Phostensin_N PF13916.1 CDI75528.1 - 0.0036 17.2 2.6 0.0036 17.2 1.8 8.4 7 2 2 9 9 9 1 PP1-regulatory protein, Phostensin N-terminal RAB3GAP2_N PF14655.1 CDI75528.1 - 0.02 13.9 0.4 0.02 13.9 0.3 6.0 5 1 2 7 7 7 0 Rab3 GTPase-activating protein regulatory subunit N-terminus DUF2722 PF10846.3 CDI75528.1 - 0.022 13.8 0.1 0.022 13.8 0.0 5.9 4 1 0 5 5 5 0 Protein of unknown function (DUF2722) LMBR1 PF04791.11 CDI75528.1 - 7.3 5.0 9.0 14 4.1 5.3 2.0 2 0 0 2 2 2 0 LMBR1-like membrane protein TBP PF00352.16 CDI75530.1 - 2.5e-33 113.3 0.0 8.6e-21 73.1 0.0 2.3 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.3 CDI75530.1 - 0.032 14.2 0.1 0.099 12.7 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3378) Med15 PF09606.5 CDI75531.1 - 0.002 16.4 115.4 0.002 16.4 80.0 5.3 1 1 2 5 5 5 3 ARC105 or Med15 subunit of Mediator complex non-fungal IncA PF04156.9 CDI75531.1 - 0.0034 17.0 17.7 0.0034 17.0 12.3 6.3 4 3 1 5 5 5 1 IncA protein HXXEE PF13787.1 CDI75532.1 - 1.4 9.3 5.9 31 4.9 0.0 5.5 5 0 0 5 5 5 0 Protein of unknown function with HXXEE motif DUF4201 PF13870.1 CDI75533.1 - 2e-18 66.4 23.4 2e-18 66.4 16.2 3.8 1 1 2 3 3 3 2 Domain of unknown function (DUF4201) Bestrophin PF01062.16 CDI75533.1 - 7.1 5.4 13.1 0.46 9.3 2.7 2.3 2 0 0 2 2 2 0 Bestrophin, RFP-TM, chloride channel Ank_2 PF12796.2 CDI75534.1 - 4.4e-31 107.0 10.9 3e-10 40.2 0.6 5.3 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 CDI75534.1 - 3.6e-26 89.6 12.5 5.7e-05 22.7 0.0 7.9 8 0 0 8 8 8 5 Ankyrin repeat Ank_5 PF13857.1 CDI75534.1 - 1.5e-25 88.5 14.0 5.3e-12 45.5 0.2 6.1 4 2 1 5 5 5 4 Ankyrin repeats (many copies) Ank_4 PF13637.1 CDI75534.1 - 2.6e-22 78.7 3.6 7.2e-08 32.7 0.1 6.3 3 2 4 7 7 7 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 CDI75534.1 - 1.7e-17 61.7 5.9 0.0017 18.4 0.0 7.2 7 0 0 7 7 7 4 Ankyrin repeat Sushi PF00084.15 CDI75534.1 - 2.6e-05 24.4 0.1 4.5e-05 23.7 0.1 1.4 1 0 0 1 1 1 1 Sushi domain (SCR repeat) Sec63 PF02889.11 CDI75535.1 - 2.8e-32 112.1 0.0 1.5e-26 93.3 0.0 2.2 1 1 1 2 2 2 2 Sec63 Brl domain DnaJ PF00226.26 CDI75535.1 - 4.8e-21 74.2 0.4 1.2e-20 73.0 0.3 1.7 1 0 0 1 1 1 1 DnaJ domain TIP49 PF06068.8 CDI75537.1 - 3.8e-58 197.0 15.9 1.6e-30 106.1 1.8 2.5 2 1 1 3 3 2 2 TIP49 C-terminus AAA PF00004.24 CDI75537.1 - 1e-11 45.1 2.4 2.3e-07 31.0 0.1 3.8 3 1 1 4 4 3 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 CDI75537.1 - 6.7e-09 35.1 4.7 7.2e-05 21.9 0.1 3.2 2 1 1 3 3 3 2 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 CDI75537.1 - 9.2e-09 36.1 0.7 0.0016 19.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.9 CDI75537.1 - 1e-07 31.7 1.0 0.014 15.1 0.1 2.7 1 1 1 2 2 2 2 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 CDI75537.1 - 3.6e-07 29.7 7.2 0.0029 17.0 0.4 2.9 2 1 1 3 3 3 2 AAA domain DnaB_C PF03796.10 CDI75537.1 - 1.6e-06 27.1 8.2 8e-05 21.6 0.0 3.2 2 1 1 3 3 3 2 DnaB-like helicase C terminal domain Zeta_toxin PF06414.7 CDI75537.1 - 1.4e-05 24.2 5.6 0.00098 18.2 0.6 3.4 2 2 2 4 4 2 2 Zeta toxin APS_kinase PF01583.15 CDI75537.1 - 5.1e-05 22.9 0.1 0.31 10.6 0.0 2.8 1 1 1 2 2 2 2 Adenylylsulphate kinase AAA_18 PF13238.1 CDI75537.1 - 5.5e-05 23.4 0.8 0.0085 16.3 0.0 3.3 3 1 1 4 4 2 2 AAA domain AAA_16 PF13191.1 CDI75537.1 - 9.3e-05 22.4 9.4 0.0027 17.7 3.9 4.2 2 2 1 3 3 2 2 AAA ATPase domain RNA_helicase PF00910.17 CDI75537.1 - 0.00011 22.2 0.2 0.71 10.0 0.0 3.0 1 1 1 2 2 2 2 RNA helicase DUF2075 PF09848.4 CDI75537.1 - 0.00063 18.8 1.0 0.031 13.2 0.0 4.5 4 1 1 5 5 5 2 Uncharacterized conserved protein (DUF2075) AAA_3 PF07726.6 CDI75537.1 - 0.00099 18.7 0.4 1.4 8.5 0.0 2.8 1 1 1 2 2 2 2 ATPase family associated with various cellular activities (AAA) Spt20 PF12090.3 CDI75537.1 - 0.0012 18.2 0.0 0.0012 18.2 0.0 4.1 3 1 0 3 3 2 1 Spt20 family Med15 PF09606.5 CDI75537.1 - 0.003 15.8 13.8 0.003 15.8 9.6 3.1 2 1 1 3 3 3 2 ARC105 or Med15 subunit of Mediator complex non-fungal NACHT PF05729.7 CDI75537.1 - 0.0038 16.9 2.9 0.062 12.9 0.1 3.6 4 1 1 5 5 2 2 NACHT domain AAA_19 PF13245.1 CDI75537.1 - 0.0051 16.5 1.4 0.0051 16.5 1.0 5.3 3 2 1 4 4 2 2 Part of AAA domain AAA_22 PF13401.1 CDI75537.1 - 0.0061 16.7 0.4 0.14 12.3 0.0 4.1 4 2 1 6 6 3 2 AAA domain KaiC PF06745.8 CDI75537.1 - 0.0086 15.2 7.7 0.025 13.7 0.1 2.5 2 1 1 3 3 2 1 KaiC Cytidylate_kin2 PF13189.1 CDI75537.1 - 0.012 15.5 0.8 5.1 6.9 0.1 2.8 1 1 1 2 2 2 0 Cytidylate kinase-like family DUF898 PF05987.8 CDI75537.1 - 0.015 14.2 2.8 0.025 13.4 1.9 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF898) AAA_29 PF13555.1 CDI75537.1 - 0.019 14.4 1.8 1.9 8.0 0.1 2.7 1 1 1 2 2 2 0 P-loop containing region of AAA domain SPX PF03105.14 CDI75537.1 - 0.035 13.8 14.3 0.78 9.4 3.9 3.0 3 0 0 3 3 3 0 SPX domain Suf PF05843.9 CDI75537.1 - 0.037 13.7 42.5 0.46 10.1 11.5 3.2 3 0 0 3 3 3 0 Suppressor of forked protein (Suf) IstB_IS21 PF01695.12 CDI75537.1 - 0.046 13.1 0.4 0.046 13.1 0.3 3.9 4 1 1 5 5 2 0 IstB-like ATP binding protein GvpD PF07088.6 CDI75537.1 - 0.06 11.6 0.5 4.6 5.4 0.1 2.1 1 1 1 2 2 2 0 GvpD gas vesicle protein AAA_31 PF13614.1 CDI75537.1 - 0.071 13.0 0.2 8.9 6.2 0.0 2.7 1 1 1 2 2 2 0 AAA domain ATP-synt_ab PF00006.20 CDI75537.1 - 0.072 12.5 5.8 2.2 7.7 0.1 3.1 2 1 1 3 3 3 0 ATP synthase alpha/beta family, nucleotide-binding domain CPT PF07931.7 CDI75537.1 - 0.083 12.5 7.0 1 8.9 0.1 3.3 2 1 1 3 3 2 0 Chloramphenicol phosphotransferase-like protein Spore_YhcN_YlaJ PF09580.5 CDI75537.1 - 0.23 11.5 21.2 0.23 11.5 3.8 3.3 3 0 0 3 3 3 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) NTPase_1 PF03266.10 CDI75537.1 - 0.31 10.7 5.5 4 7.1 0.1 2.8 2 1 1 3 3 2 0 NTPase Gti1_Pac2 PF09729.4 CDI75537.1 - 0.32 10.8 17.0 0.22 11.3 3.3 3.2 3 0 0 3 3 3 0 Gti1/Pac2 family DUF3464 PF11947.3 CDI75537.1 - 0.38 10.2 18.7 2.4 7.6 0.0 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3464) FtsK_SpoIIIE PF01580.13 CDI75537.1 - 0.85 9.0 10.4 2.2 7.6 0.3 3.2 2 1 1 3 3 3 0 FtsK/SpoIIIE family SAGA-Tad1 PF12767.2 CDI75537.1 - 0.96 9.0 32.4 0.95 9.0 7.3 3.2 3 0 0 3 3 3 0 Transcriptional regulator of RNA polII, SAGA, subunit Spore_coat_CotO PF14153.1 CDI75537.1 - 2 7.8 36.0 0.039 13.4 5.8 3.3 3 0 0 3 3 3 0 Spore coat protein CotO Hid1 PF12722.2 CDI75537.1 - 3.7 5.1 19.1 0.88 7.1 5.4 2.9 3 0 0 3 3 3 0 High-temperature-induced dauer-formation protein Mg_chelatase PF01078.16 CDI75537.1 - 5.8 6.0 22.8 0.15 11.2 0.1 4.0 3 1 1 4 4 3 0 Magnesium chelatase, subunit ChlI DUF1635 PF07795.6 CDI75539.1 - 0.1 11.9 12.8 0.18 11.1 8.6 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1635) MutS_II PF05188.12 CDI75539.1 - 0.2 11.7 3.8 0.15 12.0 0.8 2.0 1 1 1 2 2 2 0 MutS domain II Met_synt_B12 PF02965.12 CDI75539.1 - 0.41 9.8 9.1 2.9 7.0 1.4 2.3 1 1 1 2 2 2 0 Vitamin B12 dependent methionine synthase, activation domain Imm35 PF15581.1 CDI75539.1 - 1.9 8.5 3.9 9 6.3 1.3 2.3 2 0 0 2 2 2 0 Immunity protein 35 PAT1 PF09770.4 CDI75539.1 - 8 4.5 27.9 9 4.3 19.3 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 PsaN PF05479.6 CDI75539.1 - 9 6.2 20.0 2.3 8.2 0.6 3.5 1 1 2 3 3 3 0 Photosystem I reaction centre subunit N (PSAN or PSI-N) Ribosomal_60s PF00428.14 CDI75540.1 - 0.0072 16.7 2.8 0.0072 16.7 1.9 2.6 2 0 0 2 2 2 1 60s Acidic ribosomal protein Peptidase_MA_2 PF13485.1 CDI75540.1 - 0.072 13.1 0.1 0.16 12.0 0.1 1.6 1 0 0 1 1 1 0 Peptidase MA superfamily DUF2029 PF09594.5 CDI75541.1 - 2.7e-05 23.7 23.8 0.00028 20.4 2.8 3.2 2 1 1 3 3 3 2 Protein of unknown function (DUF2029) DUF21 PF01595.15 CDI75541.1 - 1.3 8.2 15.0 1.3 8.3 1.9 3.1 3 0 0 3 3 3 0 Domain of unknown function DUF21 Ribosomal_60s PF00428.14 CDI75542.1 - 0.021 15.2 5.6 0.021 15.2 3.9 4.2 2 1 2 4 4 4 0 60s Acidic ribosomal protein SPX PF03105.14 CDI75542.1 - 0.052 13.3 13.3 0.073 12.8 9.2 1.2 1 0 0 1 1 1 0 SPX domain Phage_int_SAM_1 PF02899.12 CDI75542.1 - 0.099 12.8 4.8 4.2 7.6 0.1 2.8 2 0 0 2 2 2 0 Phage integrase, N-terminal SAM-like domain Med15 PF09606.5 CDI75542.1 - 0.1 10.7 28.4 0.032 12.4 10.5 2.1 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal MSP1_C PF07462.6 CDI75542.1 - 0.58 8.4 12.5 0.12 10.7 0.5 2.1 2 0 0 2 2 2 0 Merozoite surface protein 1 (MSP1) C-terminus Glyco_transf_15 PF01793.11 CDI75542.1 - 1.1 8.1 6.9 2.2 7.1 4.8 1.4 1 0 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase Cyclin_N PF00134.18 CDI75542.1 - 1.4 8.5 5.2 1 8.8 0.1 2.2 2 0 0 2 2 2 0 Cyclin, N-terminal domain MRI PF15325.1 CDI75542.1 - 1.6 9.7 11.8 8.2 7.4 4.1 2.5 2 0 0 2 2 2 0 Modulator of retrovirus infection F-protein PF00469.15 CDI75542.1 - 1.7 7.9 7.0 4 6.7 4.9 1.6 1 0 0 1 1 1 0 Negative factor, (F-Protein) or Nef Shadoo PF14999.1 CDI75542.1 - 3.3 7.5 16.2 2.4 8.0 2.0 2.3 2 0 0 2 2 2 0 Shadow of prion protein, neuroprotective DUF913 PF06025.7 CDI75542.1 - 5.1 5.7 8.4 0.49 9.0 1.6 2.0 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) Dynamin_N PF00350.18 CDI75542.1 - 8.4 6.1 9.3 1.2 8.9 3.0 2.1 2 1 0 2 2 2 0 Dynamin family Afi1 PF07792.7 CDI75542.1 - 8.7 6.3 11.8 0.42 10.6 2.8 2.3 2 1 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Herpes_UL43 PF05072.8 CDI75543.1 - 1.9 7.1 8.4 0.66 8.6 0.9 2.3 2 0 0 2 2 2 0 Herpesvirus UL43 protein OTU PF02338.14 CDI75546.1 - 0.00051 20.6 4.1 0.0014 19.1 0.0 2.1 1 1 0 2 2 2 1 OTU-like cysteine protease Sulfatase PF00884.18 CDI75546.1 - 0.042 13.0 0.6 0.044 12.9 0.4 1.1 1 0 0 1 1 1 0 Sulfatase FNIP_N PF14636.1 CDI75546.1 - 0.076 13.4 5.6 0.11 13.0 3.9 1.2 1 0 0 1 1 1 0 Folliculin-interacting protein N-terminus SAGA-Tad1 PF12767.2 CDI75546.1 - 0.11 12.1 11.1 0.13 11.9 7.7 1.1 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit DUF4486 PF14858.1 CDI75546.1 - 0.15 10.3 2.6 0.18 10.0 1.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4486) DUF775 PF05603.7 CDI75546.1 - 0.19 11.2 8.1 0.26 10.7 5.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF775) TFIIA PF03153.8 CDI75546.1 - 0.45 10.3 20.5 0.52 10.1 14.2 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF1800 PF08811.6 CDI75546.1 - 0.76 8.6 12.0 0.88 8.4 8.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1800) Band_3_cyto PF07565.8 CDI75546.1 - 1.1 8.7 8.4 1.3 8.4 5.8 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Peptidase_S49_N PF08496.5 CDI75546.1 - 1.5 8.6 7.7 2.1 8.1 5.4 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Anoctamin PF04547.7 CDI75546.1 - 1.8 7.1 5.8 2.3 6.7 4.0 1.1 1 0 0 1 1 1 0 Calcium-activated chloride channel eIF3g PF12353.3 CDI75546.1 - 1.8 8.4 10.0 0.46 10.4 3.3 2.0 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit G PAT1 PF09770.4 CDI75546.1 - 2.5 6.2 35.8 2.9 6.0 24.8 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF1764 PF08576.5 CDI75546.1 - 2.9 8.7 11.0 4.5 8.1 7.7 1.2 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) Neur_chan_memb PF02932.11 CDI75546.1 - 2.9 7.7 5.0 3.7 7.3 3.5 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region CDK5_activator PF03261.10 CDI75546.1 - 3.4 6.9 8.1 4.7 6.4 5.6 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein HemX PF04375.9 CDI75546.1 - 4.2 5.8 24.6 5 5.6 17.1 1.0 1 0 0 1 1 1 0 HemX Med15 PF09606.5 CDI75546.1 - 4.9 5.2 46.5 6.1 4.9 32.2 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Serinc PF03348.10 CDI75546.1 - 8.2 5.0 5.8 12 4.5 4.0 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) AIF_C PF14721.1 CDI75546.1 - 9.1 6.5 10.5 52 4.0 7.3 1.9 1 1 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term SARG PF15385.1 CDI75547.1 - 0.03 13.6 11.9 0.036 13.4 8.3 1.0 1 0 0 1 1 1 0 Specifically androgen-regulated gene protein DUF2512 PF10710.4 CDI75547.1 - 0.033 13.6 0.3 0.033 13.6 0.2 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2512) Sec23_trunk PF04811.10 CDI75547.1 - 0.066 12.5 3.9 0.079 12.3 2.7 1.1 1 0 0 1 1 1 0 Sec23/Sec24 trunk domain DUF755 PF05501.6 CDI75547.1 - 0.071 13.1 31.0 0.13 12.3 21.5 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF755) APC_CDC26 PF10471.4 CDI75547.1 - 0.1 13.3 29.6 0.6 10.8 2.8 2.4 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit 1 SpecificRecomb PF10136.4 CDI75547.1 - 0.27 9.2 11.7 0.32 8.9 8.1 1.0 1 0 0 1 1 1 0 Site-specific recombinase WWbp PF10349.4 CDI75547.1 - 0.31 11.9 4.5 0.47 11.3 3.1 1.3 1 0 0 1 1 1 0 WW-domain ligand protein Macoilin PF09726.4 CDI75547.1 - 0.47 8.6 15.1 0.6 8.3 10.5 1.0 1 0 0 1 1 1 0 Transmembrane protein DUF2681 PF10883.3 CDI75547.1 - 1.1 9.5 20.2 0.54 10.4 5.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) DUF1754 PF08555.5 CDI75547.1 - 1.1 9.8 10.7 2.2 8.9 0.2 2.2 2 0 0 2 2 2 0 Eukaryotic family of unknown function (DUF1754) DUF1387 PF07139.6 CDI75547.1 - 1.8 8.1 10.5 2.3 7.7 7.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) DUF506 PF04720.7 CDI75547.1 - 2.4 7.7 7.6 3.1 7.3 5.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF506) Hid1 PF12722.2 CDI75547.1 - 3.9 5.0 12.2 4.9 4.7 8.5 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein PAT1 PF09770.4 CDI75547.1 - 4.8 5.2 31.8 5.6 5.0 22.0 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 CHD5 PF04420.9 CDI75547.1 - 7.1 6.2 9.6 12 5.5 2.9 2.1 2 0 0 2 2 2 0 CHD5-like protein NPH3 PF03000.9 CDI75547.1 - 7.2 6.0 11.6 0.56 9.6 0.2 2.0 1 1 1 2 2 2 0 NPH3 family PELOTA_1 PF15608.1 CDI75547.1 - 9.1 6.1 11.3 0.32 10.7 0.2 2.1 1 1 1 2 2 2 0 PELOTA RNA binding domain PAT1 PF09770.4 CDI75548.1 - 1.7 6.7 123.0 2.1 6.4 85.3 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Pkinase PF00069.20 CDI75549.1 - 8.4e-78 261.1 0.0 1.3e-77 260.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDI75549.1 - 2.2e-37 128.5 0.0 2.9e-37 128.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_1 PF00036.27 CDI75549.1 - 1.2e-16 58.6 0.9 6.3e-09 34.5 1.0 2.6 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.1 CDI75549.1 - 1.9e-12 45.9 0.5 8.1e-05 22.1 0.1 2.8 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.1 CDI75549.1 - 6.9e-12 44.1 2.8 7.8e-05 21.8 0.9 2.5 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.1 CDI75549.1 - 7e-12 45.3 0.0 1.6e-11 44.1 0.0 1.6 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.1 CDI75549.1 - 1.6e-11 43.6 1.9 1.1e-06 28.1 0.7 2.6 2 0 0 2 2 2 2 EF-hand domain pair Kinase-like PF14531.1 CDI75549.1 - 2.3e-05 23.5 0.0 6.5e-05 22.0 0.0 1.8 1 1 0 1 1 1 1 Kinase-like APH PF01636.18 CDI75549.1 - 0.0008 19.2 0.0 0.0016 18.2 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family EF-hand_9 PF14658.1 CDI75549.1 - 0.027 14.4 0.2 2.9 7.8 0.0 2.5 2 0 0 2 2 2 0 EF-hand domain Kdo PF06293.9 CDI75549.1 - 0.044 12.8 0.0 0.09 11.8 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Dockerin_1 PF00404.13 CDI75549.1 - 0.077 12.7 2.2 0.35 10.6 0.0 2.4 2 0 0 2 2 2 0 Dockerin type I repeat ApoL PF05461.6 CDI75550.1 - 0.0034 16.6 3.0 0.0081 15.4 2.1 1.6 1 0 0 1 1 1 1 Apolipoprotein L B2 PF11473.3 CDI75550.1 - 0.0091 15.5 0.2 3.8 7.1 0.0 2.5 2 0 0 2 2 2 2 RNA binding protein B2 Cas_NE0113 PF09623.5 CDI75550.1 - 0.037 13.4 0.3 0.1 12.0 0.1 1.7 2 0 0 2 2 2 0 CRISPR-associated protein NE0113 (Cas_NE0113) CHASE3 PF05227.8 CDI75550.1 - 0.078 12.6 2.4 0.15 11.7 1.7 1.5 1 0 0 1 1 1 0 CHASE3 domain Peptidase_C50 PF03568.12 CDI75550.1 - 0.094 11.3 3.1 0.12 11.0 2.2 1.1 1 0 0 1 1 1 0 Peptidase family C50 Fes1 PF08609.5 CDI75551.1 - 3.7 8.0 6.8 0.5 10.8 0.4 2.6 3 0 0 3 3 3 0 Nucleotide exchange factor Fes1 MAF_flag10 PF01973.13 CDI75552.1 - 0.072 12.5 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF115 TIP49 PF06068.8 CDI75553.1 - 3.2e-172 572.7 0.0 4.3e-172 572.3 0.0 1.2 1 0 0 1 1 1 1 TIP49 C-terminus AAA PF00004.24 CDI75553.1 - 1.6e-12 47.7 0.0 1.3e-08 35.1 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 CDI75553.1 - 7.9e-10 38.1 0.2 3.9e-07 29.3 0.0 2.3 2 0 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 CDI75553.1 - 5.4e-08 33.0 0.0 0.002 18.1 0.0 2.3 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.1 CDI75553.1 - 4.5e-07 30.0 0.0 0.015 15.4 0.0 3.1 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.9 CDI75553.1 - 9.7e-06 25.3 0.1 0.0014 18.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 CDI75553.1 - 8e-05 22.3 0.0 0.00023 20.8 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_17 PF13207.1 CDI75553.1 - 0.00032 21.4 0.0 0.00098 19.9 0.0 1.9 2 0 0 2 2 1 1 AAA domain AAA_25 PF13481.1 CDI75553.1 - 0.00036 20.0 0.0 0.00065 19.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 CDI75553.1 - 0.00042 19.5 0.3 0.016 14.3 0.1 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.12 CDI75553.1 - 0.00058 19.3 0.0 0.0011 18.4 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_14 PF13173.1 CDI75553.1 - 0.00058 19.7 0.0 0.66 9.8 0.0 2.4 2 0 0 2 2 2 2 AAA domain Sigma54_activat PF00158.21 CDI75553.1 - 0.00087 18.7 0.1 0.38 10.2 0.0 2.4 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_33 PF13671.1 CDI75553.1 - 0.00096 19.0 0.0 0.023 14.5 0.0 2.6 3 0 0 3 3 3 1 AAA domain AAA_18 PF13238.1 CDI75553.1 - 0.0012 19.1 0.0 0.0086 16.3 0.0 2.2 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 CDI75553.1 - 0.0018 17.3 0.1 0.0044 16.1 0.1 1.6 1 0 0 1 1 1 1 Zeta toxin AAA_28 PF13521.1 CDI75553.1 - 0.005 16.8 0.0 0.0093 15.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.4 CDI75553.1 - 0.012 14.6 0.0 0.049 12.6 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) NTPase_1 PF03266.10 CDI75553.1 - 0.012 15.3 0.1 0.066 12.9 0.0 2.3 2 0 0 2 2 2 0 NTPase AAA_11 PF13086.1 CDI75553.1 - 0.015 14.8 0.0 0.023 14.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain DnaB_C PF03796.10 CDI75553.1 - 0.017 14.0 0.1 0.03 13.2 0.0 1.3 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain Parvo_NS1 PF01057.12 CDI75553.1 - 0.018 13.9 0.1 0.033 13.0 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 ResIII PF04851.10 CDI75553.1 - 0.018 14.8 0.1 0.19 11.5 0.0 2.1 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit PhoH PF02562.11 CDI75553.1 - 0.027 13.7 0.1 0.056 12.6 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein PIF1 PF05970.9 CDI75553.1 - 0.028 13.3 0.0 1.5 7.6 0.0 2.2 2 0 0 2 2 2 0 PIF1-like helicase Sigma54_activ_2 PF14532.1 CDI75553.1 - 0.029 14.4 0.0 3.3 7.7 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain RNA_helicase PF00910.17 CDI75553.1 - 0.034 14.3 0.0 0.081 13.1 0.0 1.6 1 0 0 1 1 1 0 RNA helicase UPF0079 PF02367.12 CDI75553.1 - 0.057 13.0 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_23 PF13476.1 CDI75553.1 - 0.062 13.6 0.0 0.11 12.8 0.0 1.4 1 1 0 1 1 1 0 AAA domain NACHT PF05729.7 CDI75553.1 - 0.063 12.9 0.0 0.14 11.8 0.0 1.6 1 0 0 1 1 1 0 NACHT domain Torsin PF06309.6 CDI75553.1 - 0.064 13.1 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 Torsin Arch_ATPase PF01637.13 CDI75553.1 - 0.091 12.4 0.0 0.84 9.2 0.0 2.0 2 0 0 2 2 2 0 Archaeal ATPase G6PD_C PF02781.11 CDI75554.1 - 2.9e-90 302.0 0.0 8.9e-46 156.0 0.0 2.1 1 1 1 2 2 2 2 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.17 CDI75554.1 - 4.1e-48 164.0 0.0 1.4e-46 159.0 0.0 2.5 2 1 0 2 2 2 1 Glucose-6-phosphate dehydrogenase, NAD binding domain Glucosamine_iso PF01182.15 CDI75554.1 - 1.2e-36 126.3 0.0 2.1e-36 125.5 0.0 1.3 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Pantoate_transf PF02548.10 CDI75555.1 - 2e-48 164.7 2.6 4.4e-48 163.6 1.0 2.1 1 1 1 2 2 2 1 Ketopantoate hydroxymethyltransferase ApbA_C PF08546.6 CDI75555.1 - 2.3e-24 85.7 0.1 5.5e-24 84.5 0.1 1.7 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal PEP_mutase PF13714.1 CDI75555.1 - 0.0005 19.3 1.3 0.0012 18.1 0.9 1.6 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ApbA PF02558.11 CDI75555.1 - 0.05 13.0 0.0 7.7 5.9 0.0 2.5 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Rep_fac-A_C PF08646.5 CDI75556.1 - 3.5e-10 39.7 5.3 2.7e-07 30.4 3.7 3.0 1 1 0 1 1 1 1 Replication factor-A C terminal domain zinc-ribbons_6 PF07191.7 CDI75556.1 - 0.019 14.7 1.0 0.036 13.8 0.7 1.4 1 0 0 1 1 1 0 zinc-ribbons TSA PF03249.8 CDI75556.1 - 0.11 10.9 0.7 0.18 10.2 0.5 1.2 1 0 0 1 1 1 0 Type specific antigen DZR PF12773.2 CDI75556.1 - 0.13 12.1 2.1 0.26 11.1 1.5 1.5 1 0 0 1 1 1 0 Double zinc ribbon DUF2318 PF10080.4 CDI75556.1 - 0.16 11.7 1.8 0.28 10.9 1.2 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2318) tRNA_anti-codon PF01336.20 CDI75557.1 - 3.8e-05 23.4 0.0 0.00015 21.5 0.0 1.9 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain TFIIA PF03153.8 CDI75558.1 - 0.093 12.6 8.8 0.1 12.4 6.1 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Pex14_N PF04695.8 CDI75558.1 - 0.13 12.3 6.3 0.3 11.1 4.4 1.6 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Suf PF05843.9 CDI75558.1 - 1.3 8.7 5.5 1.7 8.3 3.8 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF605 PF04652.11 CDI75558.1 - 3 7.1 13.2 0.38 10.0 6.6 1.3 2 0 0 2 2 2 0 Vta1 like Tim17 PF02466.14 CDI75559.1 - 3.8e-28 98.0 5.7 5.3e-28 97.6 3.9 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family OB_NTP_bind PF07717.11 CDI75560.1 - 2.2e-12 46.8 0.0 1.2e-11 44.4 0.0 2.3 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 CDI75560.1 - 6.2e-10 39.0 0.1 1.8e-09 37.5 0.1 1.8 1 0 0 1 1 1 1 Helicase associated domain (HA2) CRAL_TRIO PF00650.15 CDI75561.1 - 1.8e-15 56.8 0.0 3.3e-15 55.9 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain GOLD_2 PF13897.1 CDI75561.1 - 0.043 14.0 0.4 1.8 8.7 0.0 2.4 1 1 1 2 2 2 0 Golgi-dynamics membrane-trafficking V_ATPase_I PF01496.14 CDI75562.1 - 0.083 10.7 0.3 0.086 10.6 0.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family cNMP_binding PF00027.24 CDI75563.1 - 0.00068 19.4 0.1 0.041 13.7 0.0 2.5 2 0 0 2 2 2 1 Cyclic nucleotide-binding domain DUF2157 PF09925.4 CDI75563.1 - 3.9 7.0 8.1 6.6 6.3 0.2 3.0 3 0 0 3 3 3 0 Predicted membrane protein (DUF2157) MIP-T3 PF10243.4 CDI75564.1 - 0.11 10.8 33.7 0.14 10.5 23.4 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 SPX PF03105.14 CDI75566.1 - 1.3 8.7 49.9 2.6 7.7 1.0 4.4 4 0 0 4 4 4 0 SPX domain EFG_II PF14492.1 CDI75567.1 - 2.2e-14 53.0 0.0 4.3e-14 52.1 0.0 1.4 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_IV PF03764.13 CDI75567.1 - 0.026 14.1 0.1 0.075 12.5 0.1 1.7 1 0 0 1 1 1 0 Elongation factor G, domain IV Apt1 PF10351.4 CDI75567.1 - 0.71 8.6 12.9 1.1 7.9 8.9 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain MAP65_ASE1 PF03999.7 CDI75567.1 - 1.9 6.9 19.8 2.8 6.4 13.7 1.1 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) RBFA PF02033.13 CDI75569.1 - 1.4e-05 25.0 0.0 5.7e-05 23.0 0.0 2.1 1 0 0 1 1 1 1 Ribosome-binding factor A DUF912 PF06024.7 CDI75569.1 - 0.049 13.6 0.2 0.049 13.6 0.1 4.5 5 0 0 5 5 5 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Scs3p PF10261.4 CDI75569.1 - 0.089 11.8 0.0 0.089 11.8 0.0 3.3 2 1 1 3 3 3 0 Inositol phospholipid synthesis and fat-storage-inducing TM PBP1_TM PF14812.1 CDI75569.1 - 0.22 11.8 0.0 0.22 11.8 0.0 4.8 5 0 0 5 5 5 0 Transmembrane domain of transglycosylase PBP1 at N-terminal PGA_cap PF09587.5 CDI75569.1 - 0.35 10.1 0.0 0.35 10.1 0.0 3.3 3 1 0 3 3 3 0 Bacterial capsule synthesis protein PGA_cap FimP PF09766.4 CDI75569.1 - 0.54 9.2 66.1 0.061 12.3 8.4 4.1 4 0 0 4 4 4 0 Fms-interacting protein PRA1 PF03208.14 CDI75569.1 - 2.7 7.2 5.6 89 2.3 3.9 2.5 1 1 0 1 1 1 0 PRA1 family protein FCP1_C PF09309.5 CDI75569.1 - 2.8 7.1 59.8 0.21 10.8 6.8 4.3 3 1 1 4 4 4 0 FCP1, C-terminal DUF1180 PF06679.7 CDI75569.1 - 4 7.3 9.8 0.64 9.9 2.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) Tim54 PF11711.3 CDI75570.1 - 0.02 13.5 22.9 0.023 13.3 15.9 1.0 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Gly_rich PF12810.2 CDI75570.1 - 0.059 12.9 0.1 0.073 12.6 0.1 1.1 1 0 0 1 1 1 0 Glycine rich protein Dirigent PF03018.9 CDI75570.1 - 0.14 11.7 0.8 0.17 11.3 0.5 1.3 1 0 0 1 1 1 0 Dirigent-like protein SDA1 PF05285.7 CDI75570.1 - 1.1 8.4 31.8 1.7 7.8 22.1 1.3 1 0 0 1 1 1 0 SDA1 Surp PF01805.15 CDI75571.1 - 0.00043 19.8 0.0 0.0012 18.4 0.0 1.8 1 0 0 1 1 1 1 Surp module Neur_chan_memb PF02932.11 CDI75571.1 - 1.7 8.5 9.0 1.9 8.3 6.2 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF3984 PF13136.1 CDI75571.1 - 6.5 5.8 11.9 10 5.2 8.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3984) CTD_bind PF04818.8 CDI75572.1 - 0.015 15.4 2.9 1.6 8.9 0.1 3.0 2 1 1 3 3 3 0 RNA polymerase II-binding domain. POX PF07526.6 CDI75572.1 - 0.033 14.4 10.2 0.028 14.6 2.9 2.2 2 0 0 2 2 2 0 Associated with HOX SPX PF03105.14 CDI75572.1 - 0.15 11.8 13.5 0.2 11.4 1.8 2.1 2 0 0 2 2 2 0 SPX domain DUF4614 PF15391.1 CDI75572.1 - 0.69 9.6 27.6 0.17 11.6 8.7 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4614) RAP1 PF07218.6 CDI75572.1 - 0.73 7.8 26.3 0.056 11.5 12.3 2.0 2 0 0 2 2 2 0 Rhoptry-associated protein 1 (RAP-1) DUF2217 PF10265.4 CDI75572.1 - 0.83 8.3 17.6 0.39 9.4 8.0 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2217) DUF1980 PF09323.5 CDI75572.1 - 2.5 7.8 6.1 5.2 6.7 4.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) RP-C_C PF11800.3 CDI75572.1 - 3.8 7.1 9.8 4.3 6.9 2.0 2.2 2 0 0 2 2 2 0 Replication protein C C-terminal region DUF566 PF04484.7 CDI75572.1 - 3.8 6.9 27.4 0.56 9.6 10.3 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF566) Ctr PF04145.10 CDI75572.1 - 6.2 6.8 7.3 10 6.1 0.7 2.4 2 0 0 2 2 2 0 Ctr copper transporter family Pex14_N PF04695.8 CDI75572.1 - 7.7 6.5 14.1 0.31 11.0 4.3 2.3 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Claudin_2 PF13903.1 CDI75573.1 - 0.31 10.6 1.1 1.2 8.8 0.8 2.0 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction DUF2232 PF09991.4 CDI75573.1 - 7 5.5 7.8 13 4.6 2.1 2.5 2 0 0 2 2 2 0 Predicted membrane protein (DUF2232) Macoilin PF09726.4 CDI75574.1 - 0.34 9.1 42.9 0.4 8.9 29.7 1.1 1 0 0 1 1 1 0 Transmembrane protein Spc7_N PF15402.1 CDI75574.1 - 0.56 8.1 39.4 0.67 7.8 27.3 1.1 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 DUF4407 PF14362.1 CDI75574.1 - 1.1 8.2 25.7 1.4 7.8 17.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Mucin PF01456.12 CDI75574.1 - 2.7 7.7 13.5 3.9 7.2 9.4 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein OmpH PF03938.9 CDI75574.1 - 5.7 6.8 30.8 2.2 8.2 15.3 2.1 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) BAF1_ABF1 PF04684.8 CDI75576.1 - 0.00017 20.5 38.2 0.00017 20.5 26.5 9.1 3 3 7 10 10 10 1 BAF1 / ABF1 chromatin reorganising factor Activator_LAG-3 PF11498.3 CDI75577.1 - 0.0043 15.8 50.0 0.0043 15.8 34.6 3.3 2 1 1 3 3 3 1 Transcriptional activator LAG-3 HMG_box PF00505.14 CDI75578.1 - 2.6e-17 62.8 4.8 7.4e-17 61.3 3.3 1.8 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 CDI75578.1 - 2.2e-06 27.9 6.7 2.2e-06 27.9 4.7 1.9 1 1 0 1 1 1 1 HMG-box domain Phage_tail_S PF05069.8 CDI75578.1 - 0.43 10.3 8.3 0.19 11.5 4.0 1.6 1 1 0 1 1 1 0 Phage virion morphogenesis family DUF3322 PF11795.3 CDI75578.1 - 0.92 9.1 8.0 0.31 10.6 1.5 2.1 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria N-term (DUF3322) ubiquitin PF00240.18 CDI75579.1 - 1.5e-61 203.6 6.5 6.3e-35 118.4 0.3 2.7 2 1 0 2 2 2 2 Ubiquitin family Rad60-SLD PF11976.3 CDI75579.1 - 4.1e-36 122.4 4.9 3.4e-20 71.4 0.3 2.6 2 1 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 CDI75579.1 - 3.4e-09 36.8 0.4 1.3e-05 25.3 0.1 3.2 2 2 0 2 2 2 2 Ubiquitin-like domain Rad60-SLD_2 PF13881.1 CDI75579.1 - 9.8e-07 28.6 0.0 0.027 14.3 0.0 2.5 2 1 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like Telomere_Sde2 PF13019.1 CDI75579.1 - 5.5e-06 26.1 0.1 0.00071 19.2 0.0 2.3 2 1 0 2 2 2 1 Telomere stability and silencing DUF2870 PF11069.3 CDI75579.1 - 6.2e-05 22.9 0.0 0.49 10.4 0.0 2.5 2 1 0 2 2 2 2 Protein of unknown function (DUF2870) DUF2407 PF10302.4 CDI75579.1 - 6.8e-05 22.9 0.0 0.067 13.3 0.0 2.2 1 1 1 2 2 2 2 DUF2407 ubiquitin-like domain CTDII PF01556.13 CDI75579.1 - 0.0088 15.9 2.4 1.2 9.0 0.2 2.2 1 1 1 2 2 2 2 DnaJ C terminal domain TUG-UBL1 PF11470.3 CDI75579.1 - 0.012 15.5 0.1 0.2 11.6 0.0 2.6 2 1 0 2 2 2 0 GLUT4 regulating protein TUG Phage_fiber_C PF06820.7 CDI75579.1 - 0.12 12.4 0.2 0.86 9.7 0.0 2.2 2 0 0 2 2 2 0 Putative prophage tail fibre C-terminus Plexin_cytopl PF08337.7 CDI75579.1 - 0.19 9.9 0.5 2.8 6.1 0.1 2.5 1 1 1 2 2 2 0 Plexin cytoplasmic RasGAP domain FERM_N PF09379.5 CDI75579.1 - 0.27 11.3 1.5 12 6.0 0.1 3.4 2 2 1 3 3 3 0 FERM N-terminal domain MS_channel PF00924.13 CDI75580.1 - 9e-19 67.6 1.3 1.3e-18 67.0 0.9 1.3 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_8 PF13833.1 CDI75580.1 - 0.014 14.9 0.0 0.027 14.0 0.0 1.4 1 0 0 1 1 1 0 EF-hand domain pair TIM PF00121.13 CDI75581.1 - 3e-88 295.0 1.6 3.4e-88 294.8 1.1 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase DUF1802 PF08819.6 CDI75581.1 - 0.041 13.4 0.0 0.072 12.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1802) Kinesin PF00225.18 CDI75582.1 - 5.9e-90 301.3 0.1 9.2e-90 300.7 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain Claudin_2 PF13903.1 CDI75583.1 - 0.00087 19.0 7.7 0.00087 19.0 5.3 2.0 1 1 1 2 2 1 1 PMP-22/EMP/MP20/Claudin tight junction DUF2899 PF11449.3 CDI75583.1 - 0.0048 16.1 5.6 0.0056 15.8 3.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2899) CD20 PF04103.10 CDI75583.1 - 0.012 15.5 2.2 0.012 15.5 1.6 2.1 1 1 1 2 2 2 0 CD20-like family CDK2AP PF09806.4 CDI75583.1 - 0.026 14.7 33.4 0.034 14.3 23.1 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein DUF4131 PF13567.1 CDI75583.1 - 0.041 13.2 1.6 0.042 13.2 0.4 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4131) TAF4 PF05236.9 CDI75583.1 - 0.096 11.9 19.3 0.14 11.3 13.4 1.2 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family OPT PF03169.10 CDI75583.1 - 0.28 9.5 4.1 0.34 9.2 2.8 1.1 1 0 0 1 1 1 0 OPT oligopeptide transporter protein SR-25 PF10500.4 CDI75583.1 - 0.39 10.1 33.6 1.4 8.2 23.3 1.7 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF4613 PF15390.1 CDI75583.1 - 0.53 8.3 12.7 0.6 8.2 8.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) Neur_chan_memb PF02932.11 CDI75583.1 - 0.63 9.8 13.7 0.74 9.6 9.5 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF912 PF06024.7 CDI75583.1 - 0.65 10.0 14.2 0.62 10.1 1.8 2.2 1 1 1 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) SOBP PF15279.1 CDI75583.1 - 0.69 10.2 13.3 0.98 9.7 9.2 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein TMEM223 PF14640.1 CDI75583.1 - 0.7 9.8 8.0 2.5 7.9 0.4 2.1 1 1 1 2 2 2 0 Transmembrane protein 223 DUF202 PF02656.10 CDI75583.1 - 0.84 9.9 7.5 24 5.2 5.2 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF202) DUF3984 PF13136.1 CDI75583.1 - 0.94 8.6 23.4 1.2 8.2 16.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3984) RskA PF10099.4 CDI75583.1 - 1.3 8.7 25.6 1.2e+02 2.3 17.8 2.1 1 1 0 1 1 1 0 Anti-sigma-K factor rskA DUF4366 PF14283.1 CDI75583.1 - 1.9 7.8 11.7 3 7.2 1.4 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4366) DUF4207 PF13904.1 CDI75583.1 - 2.7 7.3 37.2 3.9 6.7 25.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4207) PAT1 PF09770.4 CDI75583.1 - 2.7 6.1 43.0 2.8 6.0 29.8 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF1675 PF07897.6 CDI75583.1 - 2.9 7.6 21.3 3.5 7.4 14.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) Ndc1_Nup PF09531.5 CDI75583.1 - 3.8 5.8 19.5 4.4 5.5 13.5 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Myco_19_kDa PF05481.7 CDI75583.1 - 4.2 7.1 10.1 6.6 6.5 7.0 1.3 1 0 0 1 1 1 0 Mycobacterium 19 kDa lipoprotein antigen Ycf1 PF05758.7 CDI75583.1 - 4.3 4.9 11.1 5.7 4.5 7.7 1.1 1 0 0 1 1 1 0 Ycf1 FAM60A PF15396.1 CDI75583.1 - 4.4 7.0 21.7 8.7 6.0 15.1 1.4 1 1 0 1 1 1 0 Protein Family FAM60A DUF2413 PF10310.4 CDI75583.1 - 5 5.8 28.4 6 5.5 19.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) ERF PF04404.7 CDI75583.1 - 5 6.6 27.9 5.1 6.6 6.1 2.2 2 0 0 2 2 2 0 ERF superfamily Peptidase_S64 PF08192.6 CDI75583.1 - 5.1 5.3 18.7 5.7 5.1 13.0 1.0 1 0 0 1 1 1 0 Peptidase family S64 MRI PF15325.1 CDI75583.1 - 5.2 8.0 13.6 0.62 11.0 5.5 1.9 1 1 1 2 2 2 0 Modulator of retrovirus infection DUF3357 PF11837.3 CDI75583.1 - 5.7 6.8 11.3 33 4.3 6.9 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF3357) Pam17 PF08566.5 CDI75583.1 - 6.4 6.4 14.1 6.4 6.4 3.0 2.1 1 1 1 2 2 2 0 Mitochondrial import protein Pam17 CD99L2 PF12301.3 CDI75583.1 - 7.4 6.2 14.7 0.32 10.6 3.0 2.2 1 1 1 2 2 2 0 CD99 antigen like protein 2 DUF2146 PF10220.4 CDI75583.1 - 9.5 4.0 15.2 11 3.8 10.6 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2146) DUF2116 PF09889.4 CDI75584.1 - 0.81 9.5 3.3 16 5.3 0.3 2.4 2 0 0 2 2 2 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) Ribosomal_60s PF00428.14 CDI75585.1 - 0.003 17.9 17.7 0.0041 17.4 12.2 1.3 1 0 0 1 1 1 1 60s Acidic ribosomal protein DUF3138 PF11336.3 CDI75585.1 - 0.0052 15.0 9.5 0.0055 14.9 6.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3138) TMF_DNA_bd PF12329.3 CDI75585.1 - 0.0057 16.4 7.3 0.18 11.6 0.1 2.1 2 0 0 2 2 2 2 TATA element modulatory factor 1 DNA binding Baculo_p24 PF05073.7 CDI75585.1 - 0.032 13.7 0.4 0.24 10.9 0.2 1.9 1 1 0 1 1 1 0 Baculovirus P24 capsid protein DUF4200 PF13863.1 CDI75585.1 - 0.044 13.7 4.9 0.055 13.4 3.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) Shadoo PF14999.1 CDI75585.1 - 0.045 13.6 5.6 0.044 13.6 3.9 1.2 1 0 0 1 1 1 0 Shadow of prion protein, neuroprotective AAA_23 PF13476.1 CDI75585.1 - 0.11 12.7 0.2 0.13 12.5 0.2 1.1 1 0 0 1 1 1 0 AAA domain DUF3987 PF13148.1 CDI75585.1 - 0.12 10.9 7.3 0.14 10.7 5.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) Paralemmin PF03285.10 CDI75585.1 - 0.12 11.7 5.0 0.14 11.5 3.5 1.1 1 0 0 1 1 1 0 Paralemmin UPF0565 PF10561.4 CDI75585.1 - 0.38 9.5 2.7 0.4 9.5 1.9 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0565 DSBA PF01323.15 CDI75585.1 - 0.5 9.8 5.8 0.54 9.7 4.0 1.0 1 0 0 1 1 1 0 DSBA-like thioredoxin domain OmpH PF03938.9 CDI75585.1 - 0.63 9.9 13.6 0.76 9.7 9.4 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Seryl_tRNA_N PF02403.17 CDI75585.1 - 0.64 10.0 7.4 0.79 9.7 5.1 1.2 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Lzipper-MIP1 PF14389.1 CDI75585.1 - 0.64 10.1 7.8 2.4 8.3 5.4 1.8 1 1 0 1 1 1 0 Leucine-zipper of ternary complex factor MIP1 TSC22 PF01166.13 CDI75585.1 - 0.7 9.8 3.5 3.6 7.6 0.6 2.2 2 0 0 2 2 2 0 TSC-22/dip/bun family DUF3373 PF11853.3 CDI75585.1 - 0.9 7.9 5.3 0.6 8.5 3.0 1.2 1 1 0 1 1 1 0 Protein of unknown function (DUF3373) DUF2057 PF09829.4 CDI75585.1 - 1.1 8.8 6.8 1.3 8.5 4.7 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2057) V-SNARE PF05008.10 CDI75585.1 - 1.4 9.1 8.2 0.39 10.9 2.5 2.0 1 1 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus FUSC PF04632.7 CDI75585.1 - 1.9 6.8 12.1 2.1 6.6 8.4 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family Bap31 PF05529.7 CDI75585.1 - 2.1 7.7 5.2 2.5 7.5 3.6 1.1 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like HlyD PF00529.15 CDI75585.1 - 5.2 6.2 15.5 5.7 6.1 10.7 1.1 1 0 0 1 1 1 0 HlyD family secretion protein DivIVA PF05103.8 CDI75585.1 - 6.3 6.8 11.9 7.7 6.5 8.2 1.1 1 0 0 1 1 1 0 DivIVA protein SlyX PF04102.7 CDI75585.1 - 6.5 7.1 6.8 11 6.5 2.3 2.1 1 1 1 2 2 2 0 SlyX PepSY_2 PF13670.1 CDI75585.1 - 8.9 6.2 13.9 17 5.4 9.6 1.4 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain SMC_N PF02463.14 CDI75586.1 - 2.1e-08 33.6 2.6 2.1e-08 33.6 1.8 2.3 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 CDI75586.1 - 5.5e-05 23.2 0.0 6.3e-05 23.0 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_15 PF13175.1 CDI75586.1 - 0.00014 21.1 0.0 0.00023 20.3 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain DUF1244 PF06844.6 CDI75586.1 - 0.043 13.6 6.0 0.079 12.7 4.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1244) ODC_AZ PF02100.12 CDI75586.1 - 0.063 12.7 0.2 0.14 11.6 0.0 1.6 2 0 0 2 2 2 0 Ornithine decarboxylase antizyme CagX PF03524.10 CDI75586.1 - 0.065 12.5 1.2 0.085 12.1 0.8 1.3 1 0 0 1 1 1 0 Conjugal transfer protein RAB3GAP2_N PF14655.1 CDI75586.1 - 0.14 11.1 4.4 0.23 10.4 3.1 1.4 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus RepB PF07506.6 CDI75586.1 - 0.48 10.2 5.2 0.59 9.9 3.0 1.6 1 1 1 2 2 2 0 RepB plasmid partitioning protein DUF544 PF04424.8 CDI75586.1 - 0.5 10.1 4.7 0.26 11.1 1.8 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF544) Dehydrin PF00257.14 CDI75586.1 - 0.73 10.1 8.1 2.8 8.2 0.1 2.2 2 0 0 2 2 2 0 Dehydrin OmpH PF03938.9 CDI75586.1 - 0.9 9.4 0.0 0.9 9.4 0.0 2.1 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) SbcCD_C PF13558.1 CDI75586.1 - 1.7 8.6 9.0 0.17 11.8 2.4 2.2 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Pex14_N PF04695.8 CDI75586.1 - 4.5 7.3 16.0 15 5.6 7.0 2.2 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region ATAD4 PF15321.1 CDI75586.1 - 5.9 7.9 8.6 19 6.3 3.4 2.2 2 0 0 2 2 2 0 ATPase family AAA domain containing 4 MRP-S31 PF15433.1 CDI75586.1 - 6.4 6.0 13.3 8.8 5.6 9.2 1.2 1 1 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 E2_bind PF08825.5 CDI75587.1 - 0.2 11.4 4.4 0.085 12.6 1.2 1.8 2 0 0 2 2 2 0 E2 binding domain NCKAP5 PF15246.1 CDI75587.1 - 9.1 5.5 16.5 13 5.0 10.6 1.8 1 1 1 2 2 2 0 Nck-associated protein 5, Peripheral clock protein Cwf_Cwc_15 PF04889.7 CDI75588.1 - 5.3 6.6 19.6 9.7 5.8 13.6 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein MAT1 PF06391.8 CDI75588.1 - 5.7 6.4 8.6 8.2 5.9 5.9 1.2 1 0 0 1 1 1 0 CDK-activating kinase assembly factor MAT1 Utp14 PF04615.8 CDI75588.1 - 6.3 4.8 22.1 6.8 4.7 15.3 1.1 1 0 0 1 1 1 0 Utp14 protein Rer1 PF03248.8 CDI75590.1 - 0.096 12.2 0.0 0.096 12.2 0.0 3.4 4 0 0 4 4 4 0 Rer1 family DUF4184 PF13803.1 CDI75590.1 - 8.5 5.6 12.1 5.7 6.1 4.2 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4184) Pex14_N PF04695.8 CDI75591.1 - 0.00015 21.7 6.4 0.00015 21.7 4.5 5.2 2 2 3 5 5 5 2 Peroxisomal membrane anchor protein (Pex14p) conserved region Hist_deacetyl PF00850.14 CDI75591.1 - 0.0046 16.3 6.4 0.86 8.8 0.0 2.3 1 1 0 2 2 2 2 Histone deacetylase domain SR-25 PF10500.4 CDI75591.1 - 0.012 15.1 8.6 0.012 15.1 5.9 5.1 4 1 0 4 4 4 0 Nuclear RNA-splicing-associated protein N6_N4_Mtase PF01555.13 CDI75591.1 - 0.03 13.7 0.0 0.43 10.0 0.0 2.7 2 1 0 2 2 2 0 DNA methylase Cupin_6 PF12852.2 CDI75591.1 - 0.052 13.1 0.0 0.052 13.1 0.0 3.1 2 1 0 3 3 3 0 Cupin Auxin_inducible PF02519.9 CDI75591.1 - 0.068 13.2 0.4 0.068 13.2 0.3 5.2 4 1 1 5 5 5 0 Auxin responsive protein Na_trans_assoc PF06512.8 CDI75591.1 - 0.35 10.8 28.1 0.0095 15.9 4.7 3.2 3 0 0 3 3 3 0 Sodium ion transport-associated TRC8_N PF13705.1 CDI75591.1 - 0.89 8.0 3.5 0.29 9.6 0.1 1.9 2 0 0 2 2 2 0 TRC8 N-terminal domain FimP PF09766.4 CDI75591.1 - 4.2 6.3 64.3 0.13 11.2 8.0 4.1 4 0 0 4 4 4 0 Fms-interacting protein DivIC PF04977.10 CDI75591.1 - 4.7 6.7 58.4 0.034 13.6 4.5 4.3 4 0 0 4 4 4 0 Septum formation initiator SR-25 PF10500.4 CDI75592.1 - 1.9 7.8 76.4 1.9 7.8 27.1 2.7 1 1 1 2 2 2 0 Nuclear RNA-splicing-associated protein Raftlin PF15250.1 CDI75592.1 - 5.2 5.4 46.5 0.83 8.0 10.6 2.2 2 0 0 2 2 2 0 Raftlin PBP PF01161.15 CDI75593.1 - 0.0014 18.5 0.0 0.0021 17.9 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Ecm29 PF13001.2 CDI75594.1 - 3.3e-12 45.6 8.6 1.1e-06 27.4 1.0 2.9 3 0 0 3 3 3 2 Proteasome stabiliser HEAT PF02985.17 CDI75594.1 - 0.012 15.6 8.6 0.017 15.1 0.0 5.4 5 0 0 5 5 5 0 HEAT repeat Suf PF05843.9 CDI75594.1 - 8.5 6.0 5.6 5.1 6.7 1.4 2.5 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) zf-HIT PF04438.11 CDI75595.1 - 0.046 13.3 6.1 0.099 12.3 4.3 1.6 1 0 0 1 1 1 0 HIT zinc finger CENP-T PF15511.1 CDI75595.1 - 0.23 10.6 11.9 0.28 10.3 8.3 1.0 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Med15 PF09606.5 CDI75595.1 - 0.37 8.9 16.6 0.36 8.9 11.5 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF2052 PF09747.4 CDI75595.1 - 0.47 10.3 14.6 0.61 9.9 10.1 1.1 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) U79_P34 PF03064.11 CDI75595.1 - 0.67 9.4 13.6 0.86 9.0 9.4 1.2 1 0 0 1 1 1 0 HSV U79 / HCMV P34 ORC3_N PF07034.6 CDI75595.1 - 3.3 6.5 6.2 4.4 6.1 4.3 1.1 1 0 0 1 1 1 0 Origin recognition complex (ORC) subunit 3 N-terminus Hid1 PF12722.2 CDI75595.1 - 3.7 5.1 8.6 3.9 5.0 6.0 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Endonuc_Holl PF10107.4 CDI75595.1 - 8.1 6.1 8.4 13 5.4 5.8 1.3 1 0 0 1 1 1 0 Endonuclease related to archaeal Holliday junction resolvase DTW PF03942.10 CDI75596.1 - 1.4e-14 53.7 3.8 9.3e-08 31.5 0.1 2.8 2 1 0 2 2 2 2 DTW domain DUF2721 PF11026.3 CDI75597.1 - 0.0077 15.8 1.3 0.014 15.0 0.9 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2721) Herpes_US9 PF06072.6 CDI75597.1 - 0.021 14.6 0.7 0.021 14.6 0.5 2.1 2 1 1 3 3 3 0 Alphaherpesvirus tegument protein US9 DUF92 PF01940.11 CDI75597.1 - 0.029 13.5 2.7 0.041 13.0 1.9 1.1 1 0 0 1 1 1 0 Integral membrane protein DUF92 Abhydrolase_5 PF12695.2 CDI75597.1 - 0.047 13.4 0.0 0.081 12.6 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF21 PF01595.15 CDI75597.1 - 0.054 12.7 2.9 0.061 12.6 0.8 1.8 2 0 0 2 2 2 0 Domain of unknown function DUF21 TcpE PF12648.2 CDI75597.1 - 0.064 13.4 1.0 0.12 12.4 0.7 1.5 1 0 0 1 1 1 0 TcpE family Flavi_NS4A PF01350.12 CDI75597.1 - 0.12 11.8 2.9 0.21 11.1 2.0 1.3 1 0 0 1 1 1 0 Flavivirus non-structural protein NS4A UPF0258 PF06789.7 CDI75597.1 - 0.13 12.3 0.6 0.26 11.3 0.0 1.8 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0258) Sdh_cyt PF01127.17 CDI75597.1 - 0.38 10.6 8.1 0.56 10.0 5.6 1.2 1 0 0 1 1 1 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit SieB PF14163.1 CDI75597.1 - 0.49 9.9 4.3 0.87 9.1 3.0 1.4 1 0 0 1 1 1 0 Superinfection exclusion protein B DUF677 PF05055.7 CDI75597.1 - 1.4 7.4 4.5 3.1 6.3 3.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF677) DUF1700 PF08006.6 CDI75597.1 - 9 5.5 7.4 10 5.4 4.6 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1700) WD40 PF00400.27 CDI75598.1 - 7.7e-07 28.7 4.8 0.0054 16.5 0.1 4.9 6 0 0 6 6 6 1 WD domain, G-beta repeat TFIIA PF03153.8 CDI75598.1 - 0.037 13.9 20.6 0.049 13.5 14.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SAPS PF04499.10 CDI75598.1 - 0.05 12.2 11.5 0.062 11.9 8.0 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Baculo_PP31 PF05311.6 CDI75598.1 - 0.47 9.6 12.9 0.92 8.7 9.0 1.4 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) Band_3_cyto PF07565.8 CDI75598.1 - 0.68 9.3 12.9 1 8.8 9.0 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain DNA_pol_viral_N PF00242.12 CDI75598.1 - 0.97 8.3 18.7 1.4 7.8 12.9 1.2 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain BUD22 PF09073.5 CDI75598.1 - 1.4 7.8 27.6 2.8 6.9 19.1 1.4 1 0 0 1 1 1 0 BUD22 RAP1 PF07218.6 CDI75598.1 - 1.7 6.6 8.2 2.3 6.2 5.7 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DUF2967 PF11179.3 CDI75598.1 - 1.8 8.0 24.4 4.2 6.7 16.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2967) NARP1 PF12569.3 CDI75598.1 - 2 7.1 15.1 2.9 6.5 10.4 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DDRGK PF09756.4 CDI75598.1 - 2 7.7 21.1 3.1 7.1 14.6 1.3 1 0 0 1 1 1 0 DDRGK domain DUF4407 PF14362.1 CDI75598.1 - 2.5 6.9 10.4 3.5 6.4 7.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Neur_chan_memb PF02932.11 CDI75598.1 - 3.8 7.3 10.4 6.3 6.6 7.2 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF4557 PF15101.1 CDI75598.1 - 4 7.2 17.9 7.4 6.3 12.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) Dehydrin PF00257.14 CDI75598.1 - 6 7.1 25.1 9.3 6.5 12.9 2.2 2 0 0 2 2 2 0 Dehydrin DUF4175 PF13779.1 CDI75598.1 - 6.6 4.2 35.6 8.7 3.8 24.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) SR-25 PF10500.4 CDI75598.1 - 7 6.0 44.0 0.14 11.6 2.3 2.5 2 1 0 2 2 2 0 Nuclear RNA-splicing-associated protein DUF2215 PF10225.4 CDI75598.1 - 7.3 5.9 6.9 13 5.1 4.8 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) FLO_LFY PF01698.11 CDI75598.1 - 8.2 5.1 15.9 13 4.5 11.0 1.2 1 0 0 1 1 1 0 Floricaula / Leafy protein DUF1675 PF07897.6 CDI75598.1 - 8.7 6.1 18.1 16 5.2 12.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) POP1 PF06978.6 CDI75599.1 - 0.068 12.8 15.8 0.022 14.3 6.9 2.1 2 0 0 2 2 2 0 Ribonucleases P/MRP protein subunit POP1 Med15 PF09606.5 CDI75599.1 - 0.077 11.1 72.7 0.1 10.8 50.4 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF2052 PF09747.4 CDI75599.1 - 0.23 11.3 27.1 2.1 8.2 14.0 2.1 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) Ycf1 PF05758.7 CDI75599.1 - 0.37 8.4 19.2 0.037 11.7 8.5 1.9 2 0 0 2 2 2 0 Ycf1 CDC45 PF02724.9 CDI75599.1 - 0.39 8.6 18.6 0.35 8.8 9.6 2.0 2 0 0 2 2 2 0 CDC45-like protein Nop53 PF07767.6 CDI75599.1 - 0.57 9.1 30.4 0.85 8.5 21.1 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) DUF4045 PF13254.1 CDI75599.1 - 0.81 8.9 17.1 0.47 9.6 8.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4045) Spore_coat_CotO PF14153.1 CDI75599.1 - 1.4 8.3 33.7 0.37 10.2 15.0 2.1 2 0 0 2 2 2 0 Spore coat protein CotO Herpes_UL87 PF03043.9 CDI75599.1 - 1.7 6.9 13.3 2.2 6.5 9.2 1.1 1 0 0 1 1 1 0 Herpesvirus UL87 family SelP_N PF04592.9 CDI75599.1 - 2.4 7.4 31.4 2.7 7.3 14.0 2.1 2 0 0 2 2 2 0 Selenoprotein P, N terminal region DUF1510 PF07423.6 CDI75599.1 - 2.8 7.2 26.6 2.8 7.2 12.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) Lin-8 PF03353.10 CDI75599.1 - 3.1 7.0 24.5 0.43 9.8 11.1 2.1 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist Caldesmon PF02029.10 CDI75599.1 - 3.2 6.0 20.5 0.11 10.9 8.1 1.9 2 0 0 2 2 2 0 Caldesmon SprA-related PF12118.3 CDI75599.1 - 3.4 6.9 55.6 0.45 9.8 25.4 2.3 2 0 0 2 2 2 0 SprA-related family Pox_Ag35 PF03286.9 CDI75599.1 - 3.5 7.1 14.9 1 8.8 6.2 2.0 2 0 0 2 2 2 0 Pox virus Ag35 surface protein Tim54 PF11711.3 CDI75599.1 - 5.5 5.4 14.2 1.1 7.7 5.7 2.0 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 DUF3984 PF13136.1 CDI75599.1 - 8 5.5 23.6 1.5 7.9 9.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3984) Otopetrin PF03189.8 CDI75599.1 - 8.6 5.2 12.4 6.4 5.6 0.4 2.2 2 0 0 2 2 2 0 Otopetrin Med15 PF09606.5 CDI75600.1 - 0.0013 17.0 84.8 0.0013 17.0 58.8 2.7 2 1 1 3 3 3 1 ARC105 or Med15 subunit of Mediator complex non-fungal RCR PF12273.3 CDI75600.1 - 0.0017 18.9 15.3 0.0017 18.9 10.6 3.1 3 0 0 3 3 3 1 Chitin synthesis regulation, resistance to Congo red IncA PF04156.9 CDI75600.1 - 0.0033 17.0 13.6 0.0033 17.0 9.5 4.1 3 1 1 4 4 4 1 IncA protein Tetraspannin PF00335.15 CDI75600.1 - 0.42 9.8 16.5 0.15 11.2 8.3 2.4 2 1 0 2 2 2 0 Tetraspanin family Arv1 PF04161.8 CDI75600.1 - 7.8 6.3 8.0 19 5.0 5.2 1.9 1 1 0 1 1 1 0 Arv1-like family Med15 PF09606.5 CDI75601.1 - 1.6 6.8 54.2 0.035 12.3 17.8 2.1 1 1 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal Spt20 PF12090.3 CDI75601.1 - 4.9 6.4 12.7 2.4 7.4 2.2 2.4 2 0 0 2 2 2 0 Spt20 family PAT1 PF09770.4 CDI75601.1 - 8.1 4.5 31.8 2.6 6.1 13.7 2.1 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 Suf PF05843.9 CDI75601.1 - 9.8 5.8 17.9 1.2 8.8 4.4 2.1 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) FimP PF09766.4 CDI75602.1 - 0.002 17.2 13.3 0.002 17.2 9.2 3.6 3 1 0 3 3 3 1 Fms-interacting protein SprA-related PF12118.3 CDI75602.1 - 0.0032 16.8 25.0 0.0032 16.8 17.3 5.6 4 1 0 5 5 5 1 SprA-related family Peptidase_S49_N PF08496.5 CDI75602.1 - 0.012 15.3 6.1 0.012 15.3 4.2 3.4 3 0 0 3 3 3 0 Peptidase family S49 N-terminal AAA_23 PF13476.1 CDI75602.1 - 9.7 6.4 26.1 4.8 7.4 0.3 3.3 3 0 0 3 3 3 0 AAA domain Raftlin PF15250.1 CDI75603.1 - 5 5.5 25.6 5.4 5.4 17.8 1.0 1 0 0 1 1 1 0 Raftlin CKAP2_C PF15297.1 CDI75603.1 - 6.3 5.5 26.7 6.3 5.5 18.5 1.1 1 0 0 1 1 1 0 Cytoskeleton-associated protein 2 C-terminus CDC45 PF02724.9 CDI75603.1 - 7.7 4.4 26.6 8 4.3 18.5 1.0 1 0 0 1 1 1 0 CDC45-like protein Gti1_Pac2 PF09729.4 CDI75603.1 - 8.2 6.2 20.6 10 5.9 14.3 1.2 1 0 0 1 1 1 0 Gti1/Pac2 family Zip PF02535.17 CDI75603.1 - 9.3 5.1 12.6 9.3 5.1 8.7 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter Vfa1 PF08432.5 CDI75603.1 - 9.3 6.2 27.9 9.9 6.1 19.3 1.0 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 FimP PF09766.4 CDI75604.1 - 0.015 14.3 23.0 0.016 14.2 15.9 1.1 1 0 0 1 1 1 0 Fms-interacting protein Pex14_N PF04695.8 CDI75604.1 - 0.022 14.7 18.1 0.024 14.6 12.6 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region NARP1 PF12569.3 CDI75604.1 - 0.024 13.3 10.9 0.025 13.3 7.6 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Arena_RNA_pol PF06317.6 CDI75604.1 - 0.031 10.9 5.6 0.031 10.9 3.9 1.0 1 0 0 1 1 1 0 Arenavirus RNA polymerase MRP-S26 PF14943.1 CDI75604.1 - 0.034 13.6 13.7 0.035 13.6 9.5 1.1 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 Plasmodium_Vir PF05795.6 CDI75604.1 - 0.047 12.8 4.0 0.053 12.7 2.8 1.0 1 0 0 1 1 1 0 Plasmodium vivax Vir protein eIF3_subunit PF08597.5 CDI75604.1 - 0.064 12.8 13.8 0.07 12.6 9.6 1.0 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit RAB3GAP2_C PF14656.1 CDI75604.1 - 0.072 11.2 8.3 0.084 10.9 5.7 1.0 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit C-terminus DUF3306 PF11748.3 CDI75604.1 - 0.081 13.5 10.6 0.092 13.4 7.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3306) SpoIIP PF07454.6 CDI75604.1 - 0.085 12.0 12.0 0.087 11.9 8.3 1.0 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Bud13 PF09736.4 CDI75604.1 - 0.21 11.8 18.1 0.22 11.7 12.5 1.1 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex Suf PF05843.9 CDI75604.1 - 0.25 11.0 18.7 0.32 10.6 12.9 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) CDC45 PF02724.9 CDI75604.1 - 0.25 9.3 10.9 0.27 9.2 7.6 1.0 1 0 0 1 1 1 0 CDC45-like protein Muted PF14942.1 CDI75604.1 - 0.26 11.1 18.8 0.29 10.9 13.0 1.1 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein Ribosomal_L6e PF01159.14 CDI75604.1 - 0.29 11.3 9.8 0.32 11.2 6.8 1.2 1 0 0 1 1 1 0 Ribosomal protein L6e TFIIA PF03153.8 CDI75604.1 - 0.3 10.9 24.4 0.28 11.0 16.9 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF1800 PF08811.6 CDI75604.1 - 0.31 9.9 17.4 0.32 9.8 12.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1800) DHHW PF14286.1 CDI75604.1 - 0.33 10.2 12.9 0.4 9.9 9.0 1.0 1 0 0 1 1 1 0 DHHW protein Serinc PF03348.10 CDI75604.1 - 0.38 9.4 11.7 0.35 9.5 8.1 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) GOLD_2 PF13897.1 CDI75604.1 - 0.39 10.9 8.2 0.47 10.6 5.7 1.1 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking RED_N PF07808.8 CDI75604.1 - 0.4 9.8 20.0 0.42 9.7 13.9 1.1 1 0 0 1 1 1 0 RED-like protein N-terminal region EcoRI_methylase PF13651.1 CDI75604.1 - 0.42 9.6 5.5 0.44 9.5 3.8 1.1 1 0 0 1 1 1 0 Adenine-specific methyltransferase EcoRI AUX_IAA PF02309.11 CDI75604.1 - 0.44 10.2 11.0 0.48 10.1 7.6 1.1 1 0 0 1 1 1 0 AUX/IAA family PIH1 PF08190.7 CDI75604.1 - 0.46 9.8 15.7 0.43 9.9 10.9 1.1 1 0 0 1 1 1 0 pre-RNA processing PIH1/Nop17 Gti1_Pac2 PF09729.4 CDI75604.1 - 0.51 10.1 9.0 0.5 10.2 6.2 1.1 1 0 0 1 1 1 0 Gti1/Pac2 family DUF3449 PF11931.3 CDI75604.1 - 0.54 9.7 13.2 0.56 9.6 9.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3449) FAM176 PF14851.1 CDI75604.1 - 0.56 9.8 8.5 0.63 9.7 5.9 1.1 1 0 0 1 1 1 0 FAM176 family Kei1 PF08552.6 CDI75604.1 - 0.6 9.7 7.5 0.58 9.7 5.2 1.1 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 SAGA-Tad1 PF12767.2 CDI75604.1 - 0.61 9.7 14.6 0.67 9.5 10.1 1.1 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit DUF3464 PF11947.3 CDI75604.1 - 0.61 9.5 13.3 0.68 9.3 9.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) F-protein PF00469.15 CDI75604.1 - 0.62 9.3 11.4 0.6 9.4 7.9 1.1 1 0 0 1 1 1 0 Negative factor, (F-Protein) or Nef Tim54 PF11711.3 CDI75604.1 - 0.63 8.5 9.3 0.68 8.4 6.5 1.0 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 RR_TM4-6 PF06459.7 CDI75604.1 - 0.64 9.8 13.3 0.66 9.8 9.2 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF3402 PF11882.3 CDI75604.1 - 0.66 8.9 11.5 0.73 8.8 8.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3402) DUF4175 PF13779.1 CDI75604.1 - 0.71 7.5 40.1 0.76 7.3 27.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Raftlin PF15250.1 CDI75604.1 - 0.76 8.2 12.8 0.74 8.2 8.9 1.0 1 0 0 1 1 1 0 Raftlin DUF853 PF05872.7 CDI75604.1 - 0.77 8.0 9.7 0.72 8.1 6.7 1.0 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) FAM60A PF15396.1 CDI75604.1 - 0.89 9.2 9.6 0.88 9.2 6.7 1.1 1 0 0 1 1 1 0 Protein Family FAM60A BRF1 PF07741.8 CDI75604.1 - 0.91 9.7 11.8 1.1 9.4 8.2 1.3 1 0 0 1 1 1 0 Brf1-like TBP-binding domain Dala_Dala_lig_N PF01820.16 CDI75604.1 - 0.94 9.8 6.7 1.1 9.6 4.6 1.2 1 0 0 1 1 1 0 D-ala D-ala ligase N-terminus Glyco_transf_15 PF01793.11 CDI75604.1 - 0.94 8.3 12.3 0.94 8.3 8.5 1.1 1 0 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase SeqA PF03925.8 CDI75604.1 - 1 9.0 12.3 1 9.0 8.5 1.1 1 0 0 1 1 1 0 SeqA protein Spore_coat_CotO PF14153.1 CDI75604.1 - 1.1 8.6 22.5 1.3 8.4 15.6 1.1 1 0 0 1 1 1 0 Spore coat protein CotO DUF4045 PF13254.1 CDI75604.1 - 1.1 8.4 13.3 1 8.5 9.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) DUF4557 PF15101.1 CDI75604.1 - 1.1 9.0 24.3 1.2 8.9 16.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) PAT1 PF09770.4 CDI75604.1 - 1.1 7.3 34.0 1.1 7.4 23.6 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 ATAD4 PF15321.1 CDI75604.1 - 1.2 10.1 12.9 1.8 9.6 8.9 1.4 1 0 0 1 1 1 0 ATPase family AAA domain containing 4 FYDLN_acid PF09538.5 CDI75604.1 - 1.2 9.6 9.0 1.5 9.4 6.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) Hid1 PF12722.2 CDI75604.1 - 1.3 6.6 17.1 1.2 6.6 11.9 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Rtf2 PF04641.7 CDI75604.1 - 1.3 8.1 12.9 1.5 7.9 8.9 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger Maf1 PF09174.5 CDI75604.1 - 1.6 8.5 9.0 1.6 8.5 6.2 1.1 1 0 0 1 1 1 0 Maf1 regulator Dynamin_N PF00350.18 CDI75604.1 - 1.6 8.5 8.5 1.8 8.3 5.9 1.1 1 0 0 1 1 1 0 Dynamin family DUF1764 PF08576.5 CDI75604.1 - 1.8 9.3 17.1 2.4 9.0 11.9 1.1 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) Dehalogenase PF13486.1 CDI75604.1 - 1.8 7.9 9.8 2 7.7 6.8 1.0 1 0 0 1 1 1 0 Reductive dehalogenase subunit Glyco_transf_6 PF03414.8 CDI75604.1 - 1.8 6.9 8.1 1.7 7.0 5.6 1.1 1 0 0 1 1 1 0 Glycosyltransferase family 6 DUF605 PF04652.11 CDI75604.1 - 1.9 7.8 19.1 1.9 7.7 13.2 1.0 1 0 0 1 1 1 0 Vta1 like GvpL_GvpF PF06386.6 CDI75604.1 - 2 7.9 16.2 2.1 7.8 11.2 1.0 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF DUF2347 PF09804.4 CDI75604.1 - 2.1 7.5 9.7 2.2 7.4 6.7 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2347) DDRGK PF09756.4 CDI75604.1 - 2.1 7.6 21.5 2.4 7.5 14.9 1.0 1 0 0 1 1 1 0 DDRGK domain Ndc1_Nup PF09531.5 CDI75604.1 - 2.2 6.6 11.8 2.5 6.4 8.2 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF2828 PF11443.3 CDI75604.1 - 2.2 6.3 10.0 2.1 6.4 7.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) DUF2126 PF09899.4 CDI75604.1 - 2.4 6.0 9.8 2.2 6.1 6.8 1.0 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) Hom_end_hint PF05203.11 CDI75604.1 - 2.5 7.7 10.2 2.6 7.7 7.1 1.1 1 0 0 1 1 1 0 Hom_end-associated Hint CPSF100_C PF13299.1 CDI75604.1 - 2.7 8.1 12.7 2.8 8.1 8.8 1.1 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Folate_carrier PF01770.13 CDI75604.1 - 2.7 6.3 9.1 2.5 6.5 6.3 1.1 1 0 0 1 1 1 0 Reduced folate carrier RNA_pol_Rpb1_5 PF04998.12 CDI75604.1 - 2.9 7.0 9.1 2.9 7.0 6.3 1.0 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 HSP70 PF00012.15 CDI75604.1 - 2.9 5.6 11.0 3 5.6 7.6 1.0 1 0 0 1 1 1 0 Hsp70 protein Ycf1 PF05758.7 CDI75604.1 - 3 5.4 15.7 3.1 5.3 10.9 1.0 1 0 0 1 1 1 0 Ycf1 AIF_C PF14721.1 CDI75604.1 - 3.1 8.0 13.4 3.6 7.8 9.3 1.1 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Asp-B-Hydro_N PF05279.6 CDI75604.1 - 3.1 7.5 11.8 3.5 7.4 8.1 1.0 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region RP-C_C PF11800.3 CDI75604.1 - 3.1 7.4 14.7 3.2 7.4 10.2 1.1 1 0 0 1 1 1 0 Replication protein C C-terminal region Bul1_N PF04425.7 CDI75604.1 - 3.3 6.1 13.0 3.5 6.0 9.0 1.0 1 0 0 1 1 1 0 Bul1 N terminus EIIBC-GUT_N PF03612.9 CDI75604.1 - 3.4 7.2 12.1 4 7.0 8.4 1.1 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus eIF-3_zeta PF05091.7 CDI75604.1 - 3.6 6.1 18.7 3.8 6.0 13.0 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Draxin PF15550.1 CDI75604.1 - 3.6 7.1 12.8 3.9 7.0 8.9 1.0 1 0 0 1 1 1 0 Draxin Peptidase_S15 PF02129.13 CDI75604.1 - 3.6 6.9 10.7 3.6 6.9 7.5 1.1 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) CRF1 PF10380.4 CDI75604.1 - 3.7 7.9 11.2 4.2 7.7 7.7 1.1 1 0 0 1 1 1 0 Transcription factor CRF1 Gag_spuma PF03276.9 CDI75604.1 - 3.9 5.7 29.9 4.4 5.5 20.7 1.0 1 0 0 1 1 1 0 Spumavirus gag protein PBP1_TM PF14812.1 CDI75604.1 - 3.9 7.8 8.9 5.3 7.4 6.2 1.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DDHD PF02862.12 CDI75604.1 - 4 7.1 15.3 4.4 7.0 10.6 1.1 1 0 0 1 1 1 0 DDHD domain DUF913 PF06025.7 CDI75604.1 - 4.2 6.0 9.0 4.7 5.8 6.2 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) SpoVR PF04293.8 CDI75604.1 - 4.9 5.4 15.6 5.2 5.3 10.8 1.0 1 0 0 1 1 1 0 SpoVR like protein Neur_chan_memb PF02932.11 CDI75604.1 - 5 6.9 9.0 5 6.9 6.2 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF1266 PF06889.6 CDI75604.1 - 5.2 6.8 9.6 5.6 6.7 6.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1266) Otopetrin PF03189.8 CDI75604.1 - 5.4 5.9 7.1 5.5 5.8 4.9 1.0 1 0 0 1 1 1 0 Otopetrin ATP-synt_E PF05680.7 CDI75604.1 - 5.7 6.9 13.2 7.3 6.6 9.2 1.3 1 0 0 1 1 1 0 ATP synthase E chain PPP4R2 PF09184.6 CDI75604.1 - 5.8 6.3 16.1 6.2 6.2 11.2 1.0 1 0 0 1 1 1 0 PPP4R2 DUF4638 PF15472.1 CDI75604.1 - 6 6.3 10.1 6.1 6.3 7.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) Nucleo_P87 PF07267.6 CDI75604.1 - 6.1 5.4 16.0 6.5 5.3 11.1 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 DUF2203 PF09969.4 CDI75604.1 - 6.1 7.0 10.9 6.8 6.9 7.6 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) Baculo_PP31 PF05311.6 CDI75604.1 - 6.3 5.9 17.3 7.1 5.7 12.0 1.1 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) Peptidase_U57 PF05582.7 CDI75604.1 - 6.5 5.6 11.8 6.2 5.6 8.1 1.1 1 0 0 1 1 1 0 YabG peptidase U57 DUF2058 PF09831.4 CDI75604.1 - 6.7 6.5 26.6 7.8 6.3 18.4 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2058) Pex16 PF08610.5 CDI75604.1 - 6.8 5.5 13.4 7.1 5.5 9.3 1.1 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) RIC3 PF15361.1 CDI75604.1 - 7.3 6.8 14.4 8.1 6.6 10.0 1.2 1 0 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 FLO_LFY PF01698.11 CDI75604.1 - 7.6 5.2 15.5 8 5.1 10.7 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein DUF3260 PF11658.3 CDI75604.1 - 7.6 4.5 12.7 8.6 4.3 8.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3260) Peptidase_S49_N PF08496.5 CDI75604.1 - 8.8 6.1 14.5 10 5.9 10.1 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Spc7_N PF15402.1 CDI75604.1 - 8.9 4.1 16.9 8.7 4.2 11.7 1.0 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 FHIPEP PF00771.15 CDI75604.1 - 8.9 4.5 9.7 9.1 4.4 6.7 1.1 1 0 0 1 1 1 0 FHIPEP family SID-1_RNA_chan PF13965.1 CDI75604.1 - 9 4.3 10.2 8.3 4.4 7.1 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DUF2201_N PF13203.1 CDI75604.1 - 9.2 5.3 15.9 11 5.0 11.0 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain Paramyxo_ncap PF00973.14 CDI75604.1 - 9.3 4.8 12.1 9.4 4.8 8.4 1.0 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Nucleoside_tran PF01733.13 CDI75604.1 - 9.3 5.3 7.0 9.6 5.2 4.9 1.0 1 0 0 1 1 1 0 Nucleoside transporter DUF2681 PF10883.3 CDI75605.1 - 0.021 15.0 0.2 0.021 15.0 0.1 8.2 4 3 3 7 7 7 0 Protein of unknown function (DUF2681) BAF1_ABF1 PF04684.8 CDI75606.1 - 0.0037 16.1 3.8 0.0037 16.1 2.6 5.7 4 1 2 6 6 6 1 BAF1 / ABF1 chromatin reorganising factor Med15 PF09606.5 CDI75607.1 - 7.3e-06 24.4 62.7 7.3e-06 24.4 43.4 3.8 3 1 1 4 4 4 1 ARC105 or Med15 subunit of Mediator complex non-fungal Plasmodium_Vir PF05795.6 CDI75607.1 - 0.0001 21.6 6.1 0.0061 15.8 0.6 2.3 2 0 0 2 2 2 2 Plasmodium vivax Vir protein Ycf1 PF05758.7 CDI75607.1 - 0.55 7.8 28.7 0.016 12.9 0.8 2.2 2 0 0 2 2 2 0 Ycf1 SAPS PF04499.10 CDI75607.1 - 1.1 7.7 31.1 0.088 11.4 1.2 2.1 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein SPX PF03105.14 CDI75607.1 - 4.8 6.8 35.8 0.15 11.8 2.3 2.3 2 0 0 2 2 2 0 SPX domain LMBR1 PF04791.11 CDI75607.1 - 6 5.3 20.8 1.4 7.4 1.1 2.2 2 0 0 2 2 2 0 LMBR1-like membrane protein MRP-S31 PF15433.1 CDI75607.1 - 6.5 6.0 46.7 0.79 9.0 17.8 2.3 2 0 0 2 2 2 0 Mitochondrial 28S ribosomal protein S31 Pox_Ag35 PF03286.9 CDI75607.1 - 6.7 6.1 26.3 2.7 7.4 5.9 2.3 2 0 0 2 2 2 0 Pox virus Ag35 surface protein Herpes_UL87 PF03043.9 CDI75608.1 - 0.027 12.8 3.9 0.03 12.7 2.7 1.1 1 0 0 1 1 1 0 Herpesvirus UL87 family DUF2371 PF10177.4 CDI75608.1 - 0.037 13.9 3.8 0.13 12.1 2.6 1.9 1 1 0 1 1 1 0 Uncharacterised conserved protein (DUF2371) PRP38_assoc PF12871.2 CDI75608.1 - 0.041 14.3 28.2 0.15 12.5 19.5 1.9 1 0 0 1 1 1 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term Gastrin PF00918.12 CDI75608.1 - 0.066 14.0 0.5 0.066 14.0 0.3 3.2 3 0 0 3 3 3 0 Gastrin/cholecystokinin family YjgP_YjgQ PF03739.9 CDI75608.1 - 0.13 10.9 5.9 0.18 10.5 4.1 1.1 1 0 0 1 1 1 0 Predicted permease YjgP/YjgQ family CDC45 PF02724.9 CDI75608.1 - 0.19 9.7 25.6 0.0082 14.2 4.0 2.1 2 0 0 2 2 2 0 CDC45-like protein Rtf2 PF04641.7 CDI75608.1 - 0.19 10.8 15.9 0.051 12.7 6.5 2.1 2 0 0 2 2 2 0 Rtf2 RING-finger OSTbeta PF15048.1 CDI75608.1 - 0.37 10.8 0.0 0.37 10.8 0.0 2.8 3 0 0 3 3 3 0 Organic solute transporter subunit beta protein LMBR1 PF04791.11 CDI75608.1 - 1.1 7.7 4.1 4.6 5.6 3.5 1.6 1 1 0 1 1 1 0 LMBR1-like membrane protein DUF3824 PF12868.2 CDI75608.1 - 1.5 9.7 0.0 1.5 9.7 0.0 3.9 3 1 0 3 3 2 0 Domain of unknwon function (DUF3824) DUF4557 PF15101.1 CDI75608.1 - 2.5 7.8 35.6 0.023 14.5 14.1 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4557) DUF4199 PF13858.1 CDI75608.1 - 2.8 7.8 9.6 2.6 7.9 3.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4199) SAGA-Tad1 PF12767.2 CDI75608.1 - 4.7 6.8 29.2 1.3 8.6 9.6 3.1 3 0 0 3 3 3 0 Transcriptional regulator of RNA polII, SAGA, subunit DUF2324 PF10086.4 CDI75608.1 - 9.6 5.3 9.8 4.6 6.3 0.0 2.2 2 0 0 2 2 2 0 Putative membrane peptidase family (DUF2324) Vfa1 PF08432.5 CDI75609.1 - 0.56 10.2 15.0 0.62 10.0 10.4 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 SDA1 PF05285.7 CDI75609.1 - 0.68 9.1 15.7 0.69 9.1 10.8 1.0 1 0 0 1 1 1 0 SDA1 FRG2 PF15315.1 CDI75609.1 - 1.9 8.4 10.1 2.1 8.2 7.0 1.1 1 0 0 1 1 1 0 Facioscapulohumeral muscular dystrophy candidate 2 Rtf2 PF04641.7 CDI75609.1 - 5.3 6.1 15.0 5.6 6.0 10.4 1.0 1 0 0 1 1 1 0 Rtf2 RING-finger Nop14 PF04147.7 CDI75609.1 - 5.7 4.7 16.5 5.9 4.6 11.4 1.0 1 0 0 1 1 1 0 Nop14-like family DUF1510 PF07423.6 CDI75609.1 - 6.4 6.0 24.0 7.2 5.9 16.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DUF3513 PF12026.3 CDI75609.1 - 8.9 5.7 8.4 9.7 5.6 5.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3513) IMPDH PF00478.20 CDI75611.1 - 4.7e-135 450.0 0.0 6.7e-86 288.3 6.4 2.3 1 1 1 2 2 2 2 IMP dehydrogenase / GMP reductase domain NMO PF03060.10 CDI75611.1 - 6.4e-14 51.8 2.5 8e-10 38.3 0.4 2.9 3 0 0 3 3 3 2 Nitronate monooxygenase CBS PF00571.23 CDI75611.1 - 1.2e-13 50.5 0.1 2.8e-06 27.0 0.0 2.9 3 0 0 3 3 3 2 CBS domain FMN_dh PF01070.13 CDI75611.1 - 1.9e-09 36.8 3.8 1.9e-09 36.8 1.2 1.9 2 0 0 2 2 2 1 FMN-dependent dehydrogenase His_biosynth PF00977.16 CDI75611.1 - 3.5e-06 26.4 3.8 0.00026 20.3 2.6 3.2 1 1 0 1 1 1 1 Histidine biosynthesis protein NanE PF04131.9 CDI75611.1 - 0.00035 19.5 1.2 0.35 9.8 0.0 3.2 2 1 0 3 3 3 2 Putative N-acetylmannosamine-6-phosphate epimerase ThiG PF05690.9 CDI75611.1 - 0.00058 19.0 1.1 0.0012 18.0 0.8 1.5 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG PcrB PF01884.12 CDI75611.1 - 0.013 14.7 3.7 2 7.6 0.1 3.4 2 1 1 3 3 3 0 PcrB family DHO_dh PF01180.16 CDI75611.1 - 0.016 14.1 1.0 0.03 13.2 0.2 1.7 1 1 0 2 2 2 0 Dihydroorotate dehydrogenase Response_reg PF00072.19 CDI75611.1 - 0.035 14.1 0.1 0.16 11.9 0.0 2.3 2 0 0 2 2 1 0 Response regulator receiver domain TMP-TENI PF02581.12 CDI75611.1 - 0.051 12.6 2.7 0.24 10.5 1.6 2.3 2 1 0 2 2 2 0 Thiamine monophosphate synthase/TENI Exo_endo_phos PF03372.18 CDI75612.1 - 5.4e-06 26.5 0.0 9.6e-05 22.4 0.0 2.5 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Pkinase PF00069.20 CDI75613.1 - 3.6e-38 131.2 0.0 5.4e-38 130.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDI75613.1 - 6.1e-24 84.4 0.0 9.6e-24 83.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CDI75613.1 - 0.0075 16.0 0.3 0.015 15.0 0.1 1.6 2 0 0 2 2 2 1 Phosphotransferase enzyme family LRV PF01816.12 CDI75614.1 - 0.079 13.1 3.4 0.34 11.1 2.4 2.3 1 0 0 1 1 1 0 Leucine rich repeat variant PAM2 PF07145.10 CDI75615.1 - 1.6e-05 24.0 1.7 3.7e-05 22.9 1.2 1.7 1 0 0 1 1 1 1 Ataxin-2 C-terminal region Mucin PF01456.12 CDI75616.1 - 0.0032 17.2 15.4 0.0032 17.2 10.6 5.0 1 1 3 4 4 4 1 Mucin-like glycoprotein Bud13 PF09736.4 CDI75616.1 - 0.27 11.4 7.5 0.14 12.3 3.8 1.6 2 0 0 2 2 2 0 Pre-mRNA-splicing factor of RES complex SOBP PF15279.1 CDI75616.1 - 1.4 9.1 31.6 0.69 10.2 13.6 2.1 2 0 0 2 2 2 0 Sine oculis-binding protein GrpE PF01025.14 CDI75619.1 - 1e-31 109.6 11.8 4.9e-31 107.5 8.2 2.2 1 1 0 1 1 1 1 GrpE Tir_receptor_N PF07490.6 CDI75619.1 - 0.0047 16.5 6.3 0.0064 16.1 4.3 1.1 1 0 0 1 1 1 1 Translocated intimin receptor (Tir) N-terminus Spt20 PF12090.3 CDI75619.1 - 0.016 14.5 3.4 0.018 14.4 2.3 1.3 1 0 0 1 1 1 0 Spt20 family Nop16 PF09420.5 CDI75619.1 - 0.016 15.2 6.0 0.023 14.7 4.2 1.3 1 0 0 1 1 1 0 Ribosome biogenesis protein Nop16 DUF3371 PF11851.3 CDI75619.1 - 0.028 15.0 8.9 0.053 14.2 6.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3371) Dot_icm_IcmQ PF09475.5 CDI75619.1 - 0.039 13.1 2.9 0.057 12.6 2.0 1.3 1 0 0 1 1 1 0 Dot/Icm secretion system protein (dot_icm_IcmQ) Med15 PF09606.5 CDI75619.1 - 0.067 11.3 20.6 0.066 11.4 14.3 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal RAB3GAP2_N PF14655.1 CDI75619.1 - 0.082 11.9 5.3 0.11 11.4 3.7 1.2 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Cwf_Cwc_15 PF04889.7 CDI75619.1 - 0.084 12.5 14.2 0.11 12.1 9.9 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein FH2 PF02181.18 CDI75619.1 - 0.1 11.4 6.7 0.13 11.1 4.7 1.1 1 0 0 1 1 1 0 Formin Homology 2 Domain Muted PF14942.1 CDI75619.1 - 0.11 12.3 11.3 0.17 11.7 7.8 1.4 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein Bac_luciferase PF00296.15 CDI75619.1 - 0.15 11.1 2.3 0.19 10.7 1.6 1.2 1 0 0 1 1 1 0 Luciferase-like monooxygenase SYF2 PF08231.7 CDI75619.1 - 0.25 11.4 10.5 0.55 10.3 7.3 1.6 1 1 0 1 1 1 0 SYF2 splicing factor Suf PF05843.9 CDI75619.1 - 0.28 10.8 8.8 0.35 10.5 6.1 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) SprA-related PF12118.3 CDI75619.1 - 0.54 9.5 30.0 0.69 9.1 20.8 1.1 1 0 0 1 1 1 0 SprA-related family DUF106 PF01956.11 CDI75619.1 - 0.72 9.3 3.2 0.92 9.0 2.2 1.2 1 0 0 1 1 1 0 Integral membrane protein DUF106 IpaD PF06511.6 CDI75619.1 - 0.87 8.5 9.5 0.7 8.8 5.3 1.7 1 1 0 1 1 1 0 Invasion plasmid antigen IpaD Macoilin PF09726.4 CDI75619.1 - 0.93 7.6 14.4 1.2 7.3 10.0 1.1 1 0 0 1 1 1 0 Transmembrane protein PDGLE PF13190.1 CDI75619.1 - 0.99 9.1 4.9 3.3 7.4 3.4 1.8 1 1 0 1 1 1 0 PDGLE domain ZYG-11_interact PF05884.7 CDI75619.1 - 1.1 8.2 4.7 1.2 8.1 3.2 1.2 1 0 0 1 1 1 0 Interactor of ZYG-11 DUF1664 PF07889.7 CDI75619.1 - 1.2 8.8 7.2 1.8 8.3 4.7 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) DUF972 PF06156.8 CDI75619.1 - 1.3 9.3 9.9 2.8 8.3 6.8 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF972) DUF1525 PF07511.6 CDI75619.1 - 1.6 8.7 17.1 2.5 8.0 11.6 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1525) IncA PF04156.9 CDI75619.1 - 1.8 8.1 15.6 2.4 7.6 10.8 1.2 1 0 0 1 1 1 0 IncA protein DUF2422 PF10337.4 CDI75619.1 - 3.8 6.1 8.5 4.6 5.9 5.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2422) SKIP_SNW PF02731.10 CDI75619.1 - 4.2 6.8 12.8 4.5 6.7 8.2 1.5 1 1 0 1 1 1 0 SKIP/SNW domain Spore_III_AF PF09581.5 CDI75619.1 - 6 6.6 10.2 9.4 6.0 7.1 1.3 1 0 0 1 1 1 0 Stage III sporulation protein AF (Spore_III_AF) Sox_N PF12444.3 CDI75619.1 - 8.2 7.6 11.3 4 8.5 0.4 2.3 2 0 0 2 2 2 0 Sox developmental protein N terminal FA_synthesis PF02504.10 CDI75620.1 - 2.6 6.8 6.8 4.2 6.1 4.7 1.2 1 0 0 1 1 1 0 Fatty acid synthesis protein IncA PF04156.9 CDI75621.1 - 0.0055 16.3 5.3 0.0064 16.1 3.7 1.1 1 0 0 1 1 1 1 IncA protein Claudin_2 PF13903.1 CDI75621.1 - 0.23 11.1 5.3 0.3 10.7 3.7 1.1 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction Zip PF02535.17 CDI75621.1 - 0.8 8.6 6.9 0.87 8.5 4.8 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter VIT1 PF01988.14 CDI75621.1 - 1 8.8 12.9 0.078 12.4 5.2 1.7 1 1 0 1 1 1 0 VIT family DUF4603 PF15376.1 CDI75621.1 - 3.1 4.8 9.7 3.3 4.7 6.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) Med15 PF09606.5 CDI75621.1 - 3.1 5.8 34.7 3.6 5.6 24.1 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal FHIPEP PF00771.15 CDI75621.1 - 4.6 5.4 12.1 5 5.3 8.4 1.0 1 0 0 1 1 1 0 FHIPEP family MIP-T3 PF10243.4 CDI75622.1 - 0.049 12.1 57.4 0.059 11.8 39.8 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 PAT1 PF09770.4 CDI75622.1 - 0.14 10.4 113.3 0.14 10.3 78.5 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Utp14 PF04615.8 CDI75622.1 - 0.54 8.3 59.0 0.63 8.1 40.9 1.0 1 0 0 1 1 1 0 Utp14 protein Asp-B-Hydro_N PF05279.6 CDI75622.1 - 1.6 8.5 39.3 1.8 8.3 27.2 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region DUF1675 PF07897.6 CDI75622.1 - 2.4 7.9 38.7 3.7 7.3 26.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) Caldesmon PF02029.10 CDI75622.1 - 5.6 5.2 45.0 6.9 4.9 31.2 1.1 1 0 0 1 1 1 0 Caldesmon SAGA-Tad1 PF12767.2 CDI75624.1 - 0.01 15.5 26.9 0.012 15.2 18.6 1.2 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit TFIIF_alpha PF05793.7 CDI75624.1 - 0.21 9.9 18.8 0.25 9.6 13.1 1.0 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Ycf1 PF05758.7 CDI75624.1 - 0.27 8.9 21.2 0.3 8.7 14.7 1.1 1 0 0 1 1 1 0 Ycf1 SOBP PF15279.1 CDI75624.1 - 0.91 9.8 26.8 1.2 9.4 18.6 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein Utp14 PF04615.8 CDI75624.1 - 1 7.4 38.9 1.2 7.1 26.9 1.0 1 0 0 1 1 1 0 Utp14 protein YjgP_YjgQ PF03739.9 CDI75624.1 - 1.1 7.9 9.3 1.2 7.7 6.4 1.2 1 0 0 1 1 1 0 Predicted permease YjgP/YjgQ family DUF4647 PF15504.1 CDI75624.1 - 1.6 7.5 32.5 1.9 7.2 22.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4647) Arena_RNA_pol PF06317.6 CDI75624.1 - 2.4 4.6 9.0 2.8 4.4 6.2 1.0 1 0 0 1 1 1 0 Arenavirus RNA polymerase PLRV_ORF5 PF01690.12 CDI75624.1 - 2.6 7.1 31.7 3.2 6.8 22.0 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein PAT1 PF09770.4 CDI75624.1 - 2.8 6.0 65.7 3.9 5.5 45.5 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 CRT10 PF08728.5 CDI75624.1 - 3.1 5.6 12.6 3.4 5.5 8.7 1.0 1 0 0 1 1 1 0 CRT10 DUF2215 PF10225.4 CDI75624.1 - 3.7 6.9 13.4 5.3 6.4 9.3 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) RNA_pol_Rpb1_5 PF04998.12 CDI75624.1 - 4.4 6.4 12.6 5.1 6.2 8.7 1.3 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 Paf1 PF03985.8 CDI75624.1 - 5.5 5.6 28.0 8.2 5.0 19.4 1.3 1 0 0 1 1 1 0 Paf1 Cellulose_synt PF03552.9 CDI75624.1 - 6.1 5.0 10.5 6.9 4.8 7.3 1.2 1 0 0 1 1 1 0 Cellulose synthase Macoilin PF09726.4 CDI75624.1 - 6.7 4.8 32.5 8.8 4.4 22.5 1.1 1 0 0 1 1 1 0 Transmembrane protein DUF4638 PF15472.1 CDI75624.1 - 9.1 5.7 20.3 12 5.4 14.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) RAP1 PF07218.6 CDI75625.1 - 0.45 8.5 13.2 0.96 7.4 9.1 1.5 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) FimP PF09766.4 CDI75626.1 - 0.0028 16.7 38.0 0.0083 15.2 7.5 2.1 2 0 0 2 2 2 2 Fms-interacting protein IncA PF04156.9 CDI75626.1 - 0.009 15.6 5.9 0.009 15.6 4.1 2.9 3 0 0 3 3 3 1 IncA protein Conotoxin PF02950.12 CDI75626.1 - 0.16 12.7 0.7 0.16 12.7 0.5 3.2 3 1 0 3 3 3 0 Conotoxin RNA_replicase_B PF03431.8 CDI75626.1 - 0.31 9.1 7.7 0.45 8.6 5.3 1.3 1 0 0 1 1 1 0 RNA replicase, beta-chain zf-DHHC PF01529.15 CDI75626.1 - 1 8.7 13.2 0.56 9.5 0.2 2.2 2 0 0 2 2 2 0 DHHC palmitoyltransferase DUF3915 PF13054.1 CDI75626.1 - 1.4 8.8 6.1 0.82 9.6 0.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3915) OATP PF03137.15 CDI75626.1 - 3 5.7 20.2 0.14 10.1 1.8 2.2 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Pertussis_S1 PF02917.9 CDI75626.1 - 3.2 7.2 17.1 0.69 9.4 8.8 1.9 1 1 1 2 2 2 0 Pertussis toxin, subunit 1 TRM13 PF05206.9 CDI75626.1 - 6.3 5.9 15.1 1.5 8.0 1.6 2.2 2 0 0 2 2 2 0 Methyltransferase TRM13 DUF2561 PF10812.3 CDI75627.1 - 0.44 10.1 7.7 0.31 10.6 1.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2561) SAPS PF04499.10 CDI75627.1 - 1.9 7.0 27.5 2.5 6.6 19.1 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Daxx PF03344.10 CDI75628.1 - 0.013 14.0 22.7 0.015 13.8 15.7 1.1 1 0 0 1 1 1 0 Daxx Family PAT1 PF09770.4 CDI75628.1 - 0.027 12.7 53.9 0.032 12.5 37.4 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 PLRV_ORF5 PF01690.12 CDI75628.1 - 0.058 12.5 24.8 0.07 12.2 17.2 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein LMBR1 PF04791.11 CDI75628.1 - 1 7.8 9.0 1.3 7.4 6.2 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein GPCR_chapero_1 PF11904.3 CDI75628.1 - 1.7 7.7 22.3 3 6.8 15.4 1.5 1 0 0 1 1 1 0 GPCR-chaperone DHHW PF14286.1 CDI75628.1 - 2.3 7.4 17.7 3.4 6.9 12.2 1.4 1 0 0 1 1 1 0 DHHW protein Parvo_coat PF00740.13 CDI75628.1 - 6.4 5.5 28.0 7.9 5.3 19.4 1.1 1 0 0 1 1 1 0 Parvovirus coat protein VP2 Ndc1_Nup PF09531.5 CDI75628.1 - 7.6 4.8 22.4 9.7 4.4 15.6 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF1510 PF07423.6 CDI75628.1 - 8.1 5.7 34.7 16 4.7 24.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) BTV_NS2 PF04514.7 CDI75628.1 - 9.8 4.9 25.0 14 4.4 17.3 1.2 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 PAT1 PF09770.4 CDI75629.1 - 7.7e-07 27.7 26.0 7.7e-07 27.7 18.0 1.2 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 Pox_Ag35 PF03286.9 CDI75629.1 - 0.054 13.0 5.9 0.094 12.2 4.1 1.4 1 1 0 1 1 1 0 Pox virus Ag35 surface protein DUF3552 PF12072.3 CDI75629.1 - 0.44 9.7 19.3 0.97 8.6 13.4 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF3552) LMBR1 PF04791.11 CDI75629.1 - 0.55 8.7 3.2 0.67 8.4 2.2 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein RR_TM4-6 PF06459.7 CDI75629.1 - 0.57 10.0 15.0 1.1 9.1 10.4 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Band_3_cyto PF07565.8 CDI75629.1 - 1 8.7 13.8 1.6 8.2 9.5 1.3 1 0 0 1 1 1 0 Band 3 cytoplasmic domain BTV_NS2 PF04514.7 CDI75629.1 - 2.3 7.0 13.5 3.1 6.5 9.4 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Suf PF05843.9 CDI75629.1 - 3.6 7.2 22.3 5.3 6.6 15.5 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) CAF-1_p150 PF11600.3 CDI75630.1 - 1.4 8.2 55.4 1.7 7.9 38.4 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Herpes_gE PF02480.11 CDI75631.1 - 0.0069 14.6 4.2 0.0092 14.2 2.9 1.1 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E SMN PF06003.7 CDI75631.1 - 0.029 13.4 6.0 0.032 13.3 4.1 1.2 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) HemX PF04375.9 CDI75631.1 - 0.045 12.3 51.1 0.051 12.1 35.4 1.0 1 0 0 1 1 1 0 HemX OPT PF03169.10 CDI75631.1 - 0.56 8.5 2.5 0.8 8.0 1.7 1.3 1 1 0 1 1 1 0 OPT oligopeptide transporter protein Peptidase_S49_N PF08496.5 CDI75631.1 - 0.67 9.7 21.8 0.95 9.2 15.1 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Ycf1 PF05758.7 CDI75631.1 - 0.74 7.4 23.2 0.67 7.5 16.1 1.0 1 0 0 1 1 1 0 Ycf1 UPF0564 PF10595.4 CDI75631.1 - 0.94 8.3 43.0 1.1 8.1 29.8 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0564 AAA_23 PF13476.1 CDI75631.1 - 1.2 9.4 33.2 1.5 9.1 23.0 1.2 1 0 0 1 1 1 0 AAA domain CDC45 PF02724.9 CDI75631.1 - 1.3 6.9 23.3 1.3 6.9 16.1 1.1 1 0 0 1 1 1 0 CDC45-like protein DDHD PF02862.12 CDI75631.1 - 1.3 8.7 25.2 1.8 8.3 17.5 1.2 1 0 0 1 1 1 0 DDHD domain FAM60A PF15396.1 CDI75631.1 - 1.5 8.5 20.5 1.7 8.3 14.2 1.2 1 0 0 1 1 1 0 Protein Family FAM60A TrmE_N PF10396.4 CDI75631.1 - 2.3 8.1 5.1 4 7.4 3.6 1.5 1 1 0 1 1 1 0 GTP-binding protein TrmE N-terminus CD20 PF04103.10 CDI75631.1 - 3.6 7.4 20.3 1.2e+02 2.6 14.0 2.2 1 1 0 1 1 1 0 CD20-like family Hid1 PF12722.2 CDI75631.1 - 3.7 5.1 27.7 3.7 5.0 19.2 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein PPP4R2 PF09184.6 CDI75631.1 - 3.7 7.0 20.4 4.5 6.7 14.2 1.2 1 0 0 1 1 1 0 PPP4R2 PCEMA1 PF07418.6 CDI75631.1 - 5.2 6.3 12.8 5.3 6.3 8.9 1.2 1 0 0 1 1 1 0 Acidic phosphoprotein precursor PCEMA1 DUF4446 PF14584.1 CDI75631.1 - 6.4 6.5 14.7 9 6.1 10.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) Raftlin PF15250.1 CDI75631.1 - 6.4 5.1 25.9 6.7 5.1 18.0 1.1 1 0 0 1 1 1 0 Raftlin FLO_LFY PF01698.11 CDI75631.1 - 7 5.3 27.4 8 5.1 19.0 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein PMSI1 PF15322.1 CDI75631.1 - 8.1 5.4 21.8 8.8 5.3 15.1 1.1 1 0 0 1 1 1 0 Protein missing in infertile sperm 1, putative SPX PF03105.14 CDI75631.1 - 8.5 6.0 24.5 10 5.7 17.0 1.3 1 0 0 1 1 1 0 SPX domain Paf1 PF03985.8 CDI75631.1 - 8.6 4.9 32.2 10 4.6 22.3 1.2 1 0 0 1 1 1 0 Paf1 Utp14 PF04615.8 CDI75632.1 - 0.37 8.9 48.3 0.48 8.5 33.5 1.1 1 0 0 1 1 1 0 Utp14 protein SprA-related PF12118.3 CDI75634.1 - 0.00022 20.6 34.4 0.00027 20.3 23.9 1.1 1 0 0 1 1 1 1 SprA-related family AAA_23 PF13476.1 CDI75634.1 - 0.0033 17.7 7.1 0.0033 17.7 5.0 1.2 1 0 0 1 1 1 1 AAA domain Baculo_PP31 PF05311.6 CDI75634.1 - 0.0063 15.8 8.0 0.0094 15.2 5.5 1.3 1 0 0 1 1 1 1 Baculovirus 33KDa late protein (PP31) DUF500 PF04366.7 CDI75634.1 - 0.0072 15.7 1.6 0.0095 15.3 1.1 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF500) Ycf1 PF05758.7 CDI75634.1 - 0.011 13.4 6.6 0.01 13.6 4.6 1.1 1 0 0 1 1 1 0 Ycf1 IncA PF04156.9 CDI75634.1 - 0.012 15.2 18.2 0.02 14.5 12.6 1.3 1 0 0 1 1 1 0 IncA protein Activator_LAG-3 PF11498.3 CDI75634.1 - 0.014 14.2 37.0 0.016 14.0 25.7 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Med15 PF09606.5 CDI75634.1 - 0.017 13.3 42.3 0.02 13.0 29.4 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Paf1 PF03985.8 CDI75634.1 - 0.02 13.6 13.5 0.025 13.3 9.3 1.2 1 0 0 1 1 1 0 Paf1 Serinc PF03348.10 CDI75634.1 - 0.029 13.1 9.5 0.03 13.0 6.6 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) Ribosomal_60s PF00428.14 CDI75634.1 - 0.03 14.7 7.2 0.058 13.8 5.0 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein Raftlin PF15250.1 CDI75634.1 - 0.03 12.8 9.5 0.031 12.8 6.6 1.1 1 0 0 1 1 1 0 Raftlin Chorismate_synt PF01264.16 CDI75634.1 - 0.042 12.3 9.0 0.054 11.9 6.2 1.0 1 0 0 1 1 1 0 Chorismate synthase eIF-3_zeta PF05091.7 CDI75634.1 - 0.044 12.4 13.3 0.045 12.3 9.2 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) PCEMA1 PF07418.6 CDI75634.1 - 0.068 12.5 3.8 0.072 12.4 2.7 1.2 1 0 0 1 1 1 0 Acidic phosphoprotein precursor PCEMA1 CMV_1a PF12467.3 CDI75634.1 - 0.091 13.1 8.3 0.11 12.8 5.7 1.2 1 0 0 1 1 1 0 Cucumber mosaic virus 1a protein family PAT1 PF09770.4 CDI75634.1 - 0.098 10.8 31.6 0.1 10.8 21.9 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Apt1 PF10351.4 CDI75634.1 - 0.11 11.3 11.9 0.16 10.8 8.3 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain FLO_LFY PF01698.11 CDI75634.1 - 0.12 11.2 13.8 0.14 11.0 9.5 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein PA26 PF04636.8 CDI75634.1 - 0.13 10.9 5.8 0.16 10.6 4.0 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) DUF4557 PF15101.1 CDI75634.1 - 0.13 12.0 24.1 0.19 11.5 16.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) TFIIA PF03153.8 CDI75634.1 - 0.19 11.6 28.1 0.21 11.4 19.5 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit FimP PF09766.4 CDI75634.1 - 0.23 10.5 26.6 0.31 10.0 18.4 1.2 1 0 0 1 1 1 0 Fms-interacting protein Peptidase_S49_N PF08496.5 CDI75634.1 - 0.24 11.1 9.8 0.32 10.7 6.8 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Borrelia_P83 PF05262.6 CDI75634.1 - 0.24 9.5 15.4 0.26 9.5 10.7 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein AMP-binding PF00501.23 CDI75634.1 - 0.33 9.2 3.7 0.38 9.0 2.6 1.1 1 0 0 1 1 1 0 AMP-binding enzyme SpoVR PF04293.8 CDI75634.1 - 0.34 9.2 10.2 0.35 9.1 7.1 1.1 1 0 0 1 1 1 0 SpoVR like protein HemX PF04375.9 CDI75634.1 - 0.35 9.4 26.9 0.47 8.9 18.7 1.1 1 0 0 1 1 1 0 HemX Ctr PF04145.10 CDI75634.1 - 0.37 10.8 10.1 0.25 11.3 5.8 1.6 1 1 1 2 2 1 0 Ctr copper transporter family DUF4199 PF13858.1 CDI75634.1 - 0.38 10.6 8.5 0.49 10.2 5.1 1.8 2 0 0 2 2 1 0 Protein of unknown function (DUF4199) Peptidase_S15 PF02129.13 CDI75634.1 - 0.44 9.9 12.0 0.57 9.5 8.3 1.1 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) DUF4544 PF15077.1 CDI75634.1 - 0.44 10.0 3.1 0.52 9.7 2.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4544) RR_TM4-6 PF06459.7 CDI75634.1 - 0.49 10.2 14.0 0.62 9.9 9.7 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Rtf2 PF04641.7 CDI75634.1 - 0.56 9.3 12.6 0.71 9.0 8.8 1.3 1 0 0 1 1 1 0 Rtf2 RING-finger DUF2232 PF09991.4 CDI75634.1 - 0.62 9.0 8.1 1.1 8.2 5.6 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) Anoctamin PF04547.7 CDI75634.1 - 0.64 8.6 5.0 0.67 8.5 3.5 1.1 1 0 0 1 1 1 0 Calcium-activated chloride channel Shisa PF13908.1 CDI75634.1 - 0.87 9.7 14.4 1.2 9.2 10.0 1.3 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Peptidase_U57 PF05582.7 CDI75634.1 - 1.1 8.2 11.4 1.4 7.8 7.9 1.1 1 0 0 1 1 1 0 YabG peptidase U57 DUF2228 PF10228.4 CDI75634.1 - 1.1 8.7 8.2 1.4 8.4 5.7 1.1 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2228) SID-1_RNA_chan PF13965.1 CDI75634.1 - 1.2 7.1 5.8 1.4 7.0 4.0 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DUF913 PF06025.7 CDI75634.1 - 1.3 7.7 12.5 1.7 7.3 8.6 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) APG6 PF04111.7 CDI75634.1 - 1.8 7.5 17.2 2.2 7.2 11.9 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 PBP_sp32 PF07222.7 CDI75634.1 - 2.1 7.4 15.4 2.5 7.2 10.7 1.2 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Dala_Dala_lig_N PF01820.16 CDI75634.1 - 2.1 8.6 8.5 3.6 7.9 5.9 1.4 1 0 0 1 1 1 0 D-ala D-ala ligase N-terminus AAT PF03417.11 CDI75634.1 - 2.2 7.6 10.9 2.8 7.3 7.6 1.2 1 0 0 1 1 1 0 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase DUF3537 PF12056.3 CDI75634.1 - 2.3 6.8 6.7 2.7 6.6 4.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3537) Tim54 PF11711.3 CDI75634.1 - 2.3 6.7 11.0 2.7 6.4 7.7 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 F-protein PF00469.15 CDI75634.1 - 2.4 7.5 12.3 3.1 7.1 8.5 1.2 1 0 0 1 1 1 0 Negative factor, (F-Protein) or Nef Dicty_REP PF05086.7 CDI75634.1 - 2.4 5.7 8.6 2.5 5.7 5.9 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Pal1 PF08316.6 CDI75634.1 - 2.4 8.5 9.0 4.5 7.7 6.3 1.5 1 0 0 1 1 1 0 Pal1 cell morphology protein RIC3 PF15361.1 CDI75634.1 - 2.5 8.3 14.0 3.7 7.7 8.9 1.9 2 0 0 2 2 2 0 Resistance to inhibitors of cholinesterase homologue 3 Folate_carrier PF01770.13 CDI75634.1 - 2.6 6.4 8.5 3.7 5.9 5.9 1.3 1 0 0 1 1 1 0 Reduced folate carrier R_equi_Vir PF05526.6 CDI75634.1 - 2.9 7.4 12.8 4.9 6.7 8.9 1.4 1 0 0 1 1 1 0 Rhodococcus equi virulence-associated protein Spore_coat_CotO PF14153.1 CDI75634.1 - 3.1 7.2 21.6 4.4 6.7 15.0 1.2 1 0 0 1 1 1 0 Spore coat protein CotO DUF3260 PF11658.3 CDI75634.1 - 3.1 5.8 12.0 3.7 5.5 8.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3260) Het-C PF07217.6 CDI75634.1 - 3.6 5.6 11.1 4 5.5 7.7 1.2 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C DUF1764 PF08576.5 CDI75634.1 - 3.7 8.3 17.6 7.7 7.3 12.2 1.6 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) DUF853 PF05872.7 CDI75634.1 - 3.7 5.7 15.2 4.3 5.5 10.5 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) AIF_C PF14721.1 CDI75634.1 - 3.7 7.7 15.4 1.1 9.5 8.4 1.8 2 1 0 2 2 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term YABBY PF04690.8 CDI75634.1 - 4.4 7.5 9.2 7.3 6.8 6.4 1.4 1 0 0 1 1 1 0 YABBY protein SIP PF04954.8 CDI75634.1 - 4.5 7.6 10.3 6.4 7.1 7.1 1.2 1 0 0 1 1 1 0 Siderophore-interacting protein YfhO PF09586.5 CDI75634.1 - 4.6 5.1 9.8 6.3 4.6 6.8 1.2 1 0 0 1 1 1 0 Bacterial membrane protein YfhO DUF4367 PF14285.1 CDI75634.1 - 5.5 6.2 8.8 10 5.3 6.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4367) Herpes_glycop PF01528.11 CDI75634.1 - 5.9 5.4 5.4 9.2 4.8 3.7 1.4 1 0 0 1 1 1 0 Herpesvirus glycoprotein M DUF3043 PF11241.3 CDI75634.1 - 6.5 6.3 10.3 8.6 5.9 7.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) AUX_IAA PF02309.11 CDI75634.1 - 6.6 6.4 14.3 0.31 10.7 6.6 1.4 2 0 0 2 2 1 0 AUX/IAA family Zip PF02535.17 CDI75634.1 - 7 5.5 8.8 7.9 5.3 6.1 1.3 1 1 0 1 1 1 0 ZIP Zinc transporter DUF3408 PF11888.3 CDI75634.1 - 7.8 6.4 16.6 14 5.6 11.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) MARCKS PF02063.12 CDI75634.1 - 8.3 6.1 28.0 10 5.8 19.4 1.3 1 1 0 1 1 1 0 MARCKS family PGI PF00342.14 CDI75635.1 - 4.2e-95 318.9 0.0 4.6e-95 318.8 0.0 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase DER1 PF04511.10 CDI75636.1 - 2e-41 141.6 15.4 2.3e-41 141.5 10.6 1.0 1 0 0 1 1 1 1 Der1-like family Rhomboid PF01694.17 CDI75636.1 - 5e-06 26.6 16.4 7.9e-06 25.9 11.4 1.3 1 0 0 1 1 1 1 Rhomboid family OATP PF03137.15 CDI75638.1 - 1.1 7.1 3.2 2.1 6.3 2.2 1.4 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family CDC45 PF02724.9 CDI75638.1 - 2.1 6.2 12.2 5.2 4.9 0.0 2.0 2 0 0 2 2 2 0 CDC45-like protein RED_N PF07808.8 CDI75638.1 - 8 5.6 15.1 19 4.4 10.4 1.5 1 0 0 1 1 1 0 RED-like protein N-terminal region SMC_N PF02463.14 CDI75640.1 - 2.3e-06 27.0 0.5 0.00023 20.4 0.2 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 CDI75640.1 - 0.0018 18.2 0.2 0.0027 17.7 0.1 1.2 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.1 CDI75640.1 - 0.0022 18.3 0.0 0.0029 17.9 0.0 1.1 1 0 0 1 1 1 1 AAA domain Shadoo PF14999.1 CDI75640.1 - 0.11 12.3 10.6 0.19 11.5 7.4 1.4 1 0 0 1 1 1 0 Shadow of prion protein, neuroprotective AAA_29 PF13555.1 CDI75640.1 - 0.11 12.0 0.2 0.5 9.9 0.0 2.1 2 0 0 2 2 2 0 P-loop containing region of AAA domain Ribosomal_60s PF00428.14 CDI75640.1 - 0.32 11.4 13.8 0.52 10.7 9.6 1.3 1 0 0 1 1 1 0 60s Acidic ribosomal protein SR-25 PF10500.4 CDI75641.1 - 0.002 17.6 29.3 0.002 17.6 20.3 7.1 4 2 2 7 7 7 2 Nuclear RNA-splicing-associated protein Conotoxin PF02950.12 CDI75642.1 - 0.23 12.2 11.3 0.37 11.6 0.4 3.2 2 0 0 2 2 2 0 Conotoxin EphA2_TM PF14575.1 CDI75642.1 - 0.4 11.1 8.0 1 9.7 0.1 2.5 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain GRP PF07172.6 CDI75642.1 - 0.6 10.6 5.7 0.79 10.2 0.1 2.3 2 0 0 2 2 2 0 Glycine rich protein family Herpes_BLLF1 PF05109.8 CDI75642.1 - 1.2 7.0 32.1 1.5 6.7 22.2 1.2 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) Spt20 PF12090.3 CDI75642.1 - 1.2 8.4 17.4 1.2 8.4 0.6 2.2 2 0 0 2 2 2 0 Spt20 family Pex16 PF08610.5 CDI75642.1 - 3.1 6.7 19.6 4.3 6.2 7.1 2.1 2 0 0 2 2 2 0 Peroxisomal membrane protein (Pex16) RAB3GAP2_N PF14655.1 CDI75642.1 - 3.8 6.4 17.8 1.4 7.8 1.8 2.2 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus FimP PF09766.4 CDI75642.1 - 3.8 6.4 28.3 0.91 8.5 2.7 2.1 2 0 0 2 2 2 0 Fms-interacting protein zf-DHHC PF01529.15 CDI75642.1 - 7.8 5.8 7.7 26 4.1 0.0 2.2 2 0 0 2 2 2 0 DHHC palmitoyltransferase Stig1 PF04885.8 CDI75642.1 - 8.7 6.5 8.1 36 4.5 0.0 2.5 2 0 0 2 2 2 0 Stigma-specific protein, Stig1 Na_trans_assoc PF06512.8 CDI75642.1 - 9.6 6.1 12.1 4.3 7.2 4.5 2.1 2 0 0 2 2 2 0 Sodium ion transport-associated Mto2_bdg PF12808.2 CDI75643.1 - 0.0051 16.8 2.8 0.64 10.1 1.4 2.6 2 0 0 2 2 2 1 Micro-tubular organiser Mto1 C-term Mto2-binding region Syntaxin-6_N PF09177.6 CDI75643.1 - 0.059 13.7 0.5 0.14 12.5 0.3 1.6 1 0 0 1 1 1 0 Syntaxin 6, N-terminal V_ATPase_I PF01496.14 CDI75643.1 - 0.51 8.1 0.2 0.72 7.6 0.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TPR_MLP1_2 PF07926.7 CDI75643.1 - 1.8 8.3 9.7 0.076 12.7 2.2 1.9 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein DUF2968 PF11180.3 CDI75643.1 - 3.5 6.9 8.1 0.24 10.7 1.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2968) IncA PF04156.9 CDI75643.1 - 8.8 5.8 9.3 0.67 9.5 3.0 1.6 2 0 0 2 2 2 0 IncA protein Glt_symporter PF03616.9 CDI75644.1 - 0.0068 14.9 0.7 0.0068 14.9 0.5 4.3 3 1 0 3 3 3 1 Sodium/glutamate symporter DUF2029 PF09594.5 CDI75644.1 - 1 8.8 39.6 0.074 12.5 9.7 3.7 4 0 0 4 4 4 0 Protein of unknown function (DUF2029) SPX PF03105.14 CDI75645.1 - 5.2e-06 26.4 0.8 1.4 8.5 0.0 2.2 1 1 1 2 2 2 1 SPX domain Med15 PF09606.5 CDI75645.1 - 2.7e-05 22.6 74.0 4.5e-05 21.8 51.3 1.3 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal Ycf1 PF05758.7 CDI75645.1 - 0.00014 19.8 1.0 0.00014 19.8 0.7 1.1 1 0 0 1 1 1 1 Ycf1 FimP PF09766.4 CDI75645.1 - 0.0074 15.4 31.0 0.14 11.2 13.7 2.2 2 0 0 2 2 2 2 Fms-interacting protein Utp14 PF04615.8 CDI75645.1 - 0.13 10.3 23.3 0.2 9.8 16.2 1.2 1 0 0 1 1 1 0 Utp14 protein CDC27 PF09507.5 CDI75645.1 - 1.1 8.4 38.2 0.0092 15.2 21.0 1.5 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 PAT1 PF09770.4 CDI75645.1 - 1.7 6.7 78.6 2.6 6.1 54.5 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Apc1 PF12859.2 CDI75645.1 - 2.8 8.2 0.0 2.8 8.2 0.0 3.3 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 1 AAA_23 PF13476.1 CDI75645.1 - 5 7.4 23.2 9.7 6.4 16.1 1.4 1 0 0 1 1 1 0 AAA domain Tim54 PF11711.3 CDI75646.1 - 0.00026 19.7 4.7 0.00038 19.1 3.3 1.3 1 0 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 Mem_trans PF03547.13 CDI75646.1 - 0.00051 18.4 5.7 0.00059 18.2 3.9 1.1 1 0 0 1 1 1 1 Membrane transport protein GAGA_bind PF06217.7 CDI75646.1 - 0.00057 19.9 15.7 0.00057 19.9 10.9 1.1 1 0 0 1 1 1 1 GAGA binding protein-like family GPCR_chapero_1 PF11904.3 CDI75646.1 - 0.01 14.9 14.8 0.014 14.5 10.3 1.3 1 0 0 1 1 1 0 GPCR-chaperone Raftlin PF15250.1 CDI75646.1 - 0.025 13.1 19.5 0.03 12.8 13.5 1.1 1 0 0 1 1 1 0 Raftlin SAPS PF04499.10 CDI75646.1 - 0.029 13.0 18.7 0.036 12.7 13.0 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein PLRV_ORF5 PF01690.12 CDI75646.1 - 0.037 13.1 17.9 0.044 12.9 12.4 1.0 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Ycf1 PF05758.7 CDI75646.1 - 0.079 10.6 25.8 0.1 10.3 17.9 1.1 1 0 0 1 1 1 0 Ycf1 DUF572 PF04502.8 CDI75646.1 - 0.083 12.1 23.0 0.099 11.8 15.9 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Exonuc_VII_L PF02601.10 CDI75646.1 - 0.095 11.8 22.1 0.1 11.7 15.3 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF1510 PF07423.6 CDI75646.1 - 0.12 11.7 26.7 0.16 11.3 18.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) PA26 PF04636.8 CDI75646.1 - 0.14 10.8 15.7 0.18 10.4 10.9 1.3 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Hid1 PF12722.2 CDI75646.1 - 0.14 9.8 26.7 0.18 9.4 18.5 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF2201_N PF13203.1 CDI75646.1 - 0.18 10.9 28.3 0.23 10.5 19.6 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain Peptidase_S64 PF08192.6 CDI75646.1 - 0.18 10.1 16.3 0.2 9.9 11.3 1.1 1 0 0 1 1 1 0 Peptidase family S64 MRP-S26 PF14943.1 CDI75646.1 - 0.3 10.6 31.2 0.44 10.0 21.6 1.2 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 FLO_LFY PF01698.11 CDI75646.1 - 0.39 9.5 23.5 0.5 9.1 16.3 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein Atg14 PF10186.4 CDI75646.1 - 0.43 9.4 39.1 0.56 9.1 27.1 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 VID27 PF08553.5 CDI75646.1 - 0.47 8.6 19.1 0.53 8.4 13.2 1.0 1 0 0 1 1 1 0 VID27 cytoplasmic protein Peptidase_S46 PF10459.4 CDI75646.1 - 0.5 8.7 21.7 0.52 8.6 15.0 1.0 1 0 0 1 1 1 0 Peptidase S46 PAT1 PF09770.4 CDI75646.1 - 0.65 8.1 72.7 0.81 7.8 50.4 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF1501 PF07394.7 CDI75646.1 - 0.72 8.6 22.9 0.82 8.4 15.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) Cyto_heme_lyase PF01265.12 CDI75646.1 - 0.74 9.3 22.4 1 8.8 15.5 1.2 1 0 0 1 1 1 0 Cytochrome c/c1 heme lyase LMBR1 PF04791.11 CDI75646.1 - 0.8 8.2 13.0 1 7.8 9.0 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein SPX PF03105.14 CDI75646.1 - 0.95 9.1 25.9 1.2 8.8 18.0 1.1 1 0 0 1 1 1 0 SPX domain HSP70 PF00012.15 CDI75646.1 - 1 7.1 19.7 1.2 6.9 13.7 1.1 1 0 0 1 1 1 0 Hsp70 protein eIF-3_zeta PF05091.7 CDI75646.1 - 1.4 7.4 33.3 2.1 6.8 23.1 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) APG6 PF04111.7 CDI75646.1 - 1.4 7.8 36.6 1.9 7.4 25.4 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 HlyD_2 PF12700.2 CDI75646.1 - 1.7 7.7 26.2 2.1 7.4 18.2 1.3 1 0 0 1 1 1 0 HlyD family secretion protein DUF4045 PF13254.1 CDI75646.1 - 1.7 7.8 24.7 2.3 7.4 17.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Nha1_C PF08619.5 CDI75646.1 - 2.3 7.4 27.4 3 7.0 19.0 1.1 1 0 0 1 1 1 0 Alkali metal cation/H+ antiporter Nha1 C terminus Cellulose_synt PF03552.9 CDI75646.1 - 2.5 6.2 8.5 3.5 5.8 5.9 1.4 1 0 0 1 1 1 0 Cellulose synthase Presenilin PF01080.12 CDI75646.1 - 3.2 6.4 19.0 4.6 5.9 13.2 1.2 1 0 0 1 1 1 0 Presenilin BPL_N PF09825.4 CDI75646.1 - 4.2 6.0 12.9 5.4 5.6 8.9 1.1 1 0 0 1 1 1 0 Biotin-protein ligase, N terminal NARP1 PF12569.3 CDI75646.1 - 4.5 5.9 30.6 27 3.3 21.2 1.9 1 1 0 1 1 1 0 NMDA receptor-regulated protein 1 CDC45 PF02724.9 CDI75646.1 - 4.8 5.1 26.2 6.1 4.7 18.1 1.1 1 0 0 1 1 1 0 CDC45-like protein Ndc1_Nup PF09531.5 CDI75646.1 - 5 5.4 24.9 6 5.1 17.3 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DHHW PF14286.1 CDI75646.1 - 7.5 5.7 21.0 11 5.2 14.6 1.2 1 0 0 1 1 1 0 DHHW protein AlaDh_PNT_N PF05222.10 CDI75647.1 - 1.3e-22 80.2 0.0 1.6e-22 79.9 0.0 1.1 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain BAF1_ABF1 PF04684.8 CDI75648.1 - 0.0037 16.1 34.6 0.0037 16.1 24.0 5.2 1 1 4 5 5 5 1 BAF1 / ABF1 chromatin reorganising factor LMBR1 PF04791.11 CDI75648.1 - 0.17 10.4 7.2 0.18 10.3 4.7 1.4 1 1 0 1 1 1 0 LMBR1-like membrane protein DUF4647 PF15504.1 CDI75648.1 - 2.2 7.0 36.0 3.6 6.3 25.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4647) BTV_NS2 PF04514.7 CDI75648.1 - 4.7 5.9 19.4 9.3 5.0 13.5 1.7 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 BAF1_ABF1 PF04684.8 CDI75649.1 - 0.0021 16.9 17.0 0.0021 16.9 11.8 10.6 6 2 4 10 10 10 2 BAF1 / ABF1 chromatin reorganising factor Med15 PF09606.5 CDI75650.1 - 0.00081 17.7 66.4 0.00081 17.7 46.0 10.5 4 2 3 8 8 8 1 ARC105 or Med15 subunit of Mediator complex non-fungal Daxx PF03344.10 CDI75651.1 - 0.88 7.9 80.2 1.1 7.5 55.6 1.1 1 0 0 1 1 1 0 Daxx Family Med15 PF09606.5 CDI75652.1 - 8.5e-05 20.9 99.4 0.00011 20.6 68.9 1.0 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal CAF-1_p150 PF11600.3 CDI75652.1 - 0.0028 17.0 31.6 0.004 16.5 21.9 1.3 1 0 0 1 1 1 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal RAP1 PF07218.6 CDI75652.1 - 0.0067 14.5 0.7 0.0076 14.4 0.5 1.0 1 0 0 1 1 1 1 Rhoptry-associated protein 1 (RAP-1) MRP-S31 PF15433.1 CDI75652.1 - 0.13 11.6 38.3 0.23 10.8 26.5 1.4 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 FLO_LFY PF01698.11 CDI75652.1 - 0.17 10.6 22.4 0.25 10.1 15.5 1.4 1 0 0 1 1 1 0 Floricaula / Leafy protein PCEMA1 PF07418.6 CDI75652.1 - 0.94 8.7 12.0 1.2 8.4 8.3 1.2 1 0 0 1 1 1 0 Acidic phosphoprotein precursor PCEMA1 Ycf1 PF05758.7 CDI75652.1 - 1.2 6.7 26.4 1.4 6.5 18.3 1.0 1 0 0 1 1 1 0 Ycf1 Hid1 PF12722.2 CDI75652.1 - 6.9 4.2 34.5 8 3.9 23.9 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Sporozoite_P67 PF05642.6 CDI75653.1 - 9.4e-07 27.0 3.5 9.4e-07 27.0 2.4 10.1 3 3 7 10 10 10 1 Sporozoite P67 surface antigen Mucin PF01456.12 CDI75653.1 - 0.014 15.2 0.0 0.014 15.2 0.0 7.9 8 2 1 9 9 9 0 Mucin-like glycoprotein His_Phos_1 PF00300.17 CDI75654.1 - 3.4e-14 53.2 6.2 2.6e-13 50.3 4.0 2.4 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) SprA-related PF12118.3 CDI75654.1 - 3.6e-05 23.2 1.5 3.6e-05 23.2 1.0 4.3 2 2 0 3 3 3 1 SprA-related family Med15 PF09606.5 CDI75654.1 - 9.9e-05 20.7 78.1 0.0085 14.3 27.6 3.1 3 0 0 3 3 3 3 ARC105 or Med15 subunit of Mediator complex non-fungal RFXA_RFXANK_bdg PF15289.1 CDI75654.1 - 0.0084 16.2 1.8 0.0084 16.2 1.3 5.8 7 0 0 7 7 7 1 Regulatory factor X-associated C-terminal binding domain MIP-T3 PF10243.4 CDI75655.1 - 0.086 11.2 61.3 0.11 10.9 42.5 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 RAP1 PF07218.6 CDI75655.1 - 0.23 9.5 22.4 0.28 9.2 15.5 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) PAT1 PF09770.4 CDI75655.1 - 0.72 8.0 105.4 0.8 7.8 73.1 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 CAF-1_p150 PF11600.3 CDI75655.1 - 1.3 8.3 77.2 7.7 5.8 53.5 1.8 1 1 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal SOBP PF15279.1 CDI75655.1 - 2.2 8.5 56.1 3.4 7.9 38.9 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein Utp14 PF04615.8 CDI75655.1 - 2.3 6.3 65.9 2.8 6.0 45.7 1.0 1 0 0 1 1 1 0 Utp14 protein Pox_E2-like PF04497.7 CDI75655.1 - 5.9 4.7 6.1 7.2 4.5 4.3 1.1 1 0 0 1 1 1 0 Poxviridae protein ketoacyl-synt PF00109.21 CDI75658.1 - 3.1e-134 446.2 0.4 4.7e-67 226.1 0.1 2.3 2 0 0 2 2 2 2 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 CDI75658.1 - 1.5e-36 124.8 0.2 3.5e-36 123.6 0.1 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.20 CDI75658.1 - 1.2e-09 38.2 0.0 3.7e-09 36.7 0.0 1.9 2 0 0 2 2 2 1 Phosphopantetheine attachment site Thiolase_N PF00108.18 CDI75658.1 - 0.00012 21.1 4.8 0.0018 17.2 0.1 3.1 3 0 0 3 3 3 1 Thiolase, N-terminal domain ACP_syn_III PF08545.5 CDI75658.1 - 0.016 14.8 0.3 0.016 14.8 0.2 3.2 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III DUF503 PF04456.7 CDI75658.1 - 0.25 10.9 0.1 0.55 9.8 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF503) DUF1126 PF06565.7 CDI75659.1 - 2.1e-15 55.8 2.0 1e-11 44.0 0.0 3.2 3 0 0 3 3 3 2 Repeat of unknown function (DUF1126) EF-hand_1 PF00036.27 CDI75659.1 - 0.0017 17.4 0.2 0.0043 16.2 0.1 1.7 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.1 CDI75659.1 - 0.0034 17.4 0.1 0.009 16.1 0.0 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.1 CDI75659.1 - 0.0039 16.7 0.3 0.0088 15.6 0.2 1.6 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 CDI75659.1 - 0.082 12.8 0.0 0.31 11.0 0.0 1.9 1 0 0 1 1 1 0 EF-hand domain HEAT PF02985.17 CDI75659.1 - 0.25 11.5 7.1 2.4 8.4 0.1 5.1 5 0 0 5 5 5 0 HEAT repeat EF-hand_5 PF13202.1 CDI75659.1 - 0.36 10.2 0.0 1.1 8.7 0.0 1.8 1 0 0 1 1 1 0 EF hand Sigma70_ner PF04546.8 CDI75660.1 - 0.00036 20.2 12.6 0.00066 19.3 8.7 1.4 1 0 0 1 1 1 1 Sigma-70, non-essential region BTV_NS2 PF04514.7 CDI75660.1 - 1.3 7.8 9.5 2 7.2 6.6 1.3 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Daxx PF03344.10 CDI75660.1 - 1.4 7.3 17.3 2.6 6.4 12.0 1.4 1 0 0 1 1 1 0 Daxx Family SGT1 PF07093.6 CDI75660.1 - 4.5 5.5 18.4 6.4 5.0 12.8 1.1 1 0 0 1 1 1 0 SGT1 protein GTP_EFTU PF00009.22 CDI75663.1 - 8.4e-06 25.3 0.1 8.4e-06 25.3 0.1 1.8 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain SGT1 PF07093.6 CDI75663.1 - 0.16 10.3 19.4 0.32 9.3 6.5 2.2 2 0 0 2 2 2 0 SGT1 protein FA_desaturase PF00487.19 CDI75663.1 - 0.2 11.0 0.0 0.31 10.4 0.0 1.2 1 0 0 1 1 1 0 Fatty acid desaturase Med15 PF09606.5 CDI75664.1 - 0.0004 18.7 89.0 0.00058 18.2 45.3 2.2 2 0 0 2 2 2 2 ARC105 or Med15 subunit of Mediator complex non-fungal IncA PF04156.9 CDI75664.1 - 0.0025 17.4 9.6 0.0025 17.4 6.6 3.4 2 1 1 3 3 3 3 IncA protein PAT1 PF09770.4 CDI75664.1 - 0.71 8.0 84.6 0.05 11.8 42.2 2.2 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 Shisa PF13908.1 CDI75665.1 - 4.7 7.3 6.2 5.6 7.1 4.3 1.1 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Utp11 PF03998.8 CDI75666.1 - 7.4e-13 48.8 48.1 1.7e-12 47.6 6.8 3.1 2 1 1 3 3 3 3 Utp11 protein Herpes_PAP PF03325.8 CDI75666.1 - 0.77 9.2 7.9 0.26 10.7 3.5 1.7 1 1 1 2 2 2 0 Herpesvirus polymerase accessory protein Neisseria_TspB PF05616.8 CDI75667.1 - 1.4 7.1 7.7 3 6.1 5.3 1.5 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein Ribosomal_60s PF00428.14 CDI75669.1 - 0.0032 17.8 16.7 0.016 15.5 1.4 2.2 2 0 0 2 2 2 2 60s Acidic ribosomal protein Draxin PF15550.1 CDI75669.1 - 0.0046 16.6 5.8 0.0056 16.3 4.0 1.1 1 0 0 1 1 1 1 Draxin E1-E2_ATPase PF00122.15 CDI75669.1 - 0.008 15.2 0.1 0.013 14.5 0.0 1.4 1 1 0 1 1 1 1 E1-E2 ATPase DUF4175 PF13779.1 CDI75669.1 - 0.13 9.9 38.5 0.15 9.7 26.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Med15 PF09606.5 CDI75669.1 - 0.15 10.2 44.2 0.19 9.8 30.6 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF2370 PF10176.4 CDI75669.1 - 0.16 11.2 3.6 0.24 10.7 2.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) Hanta_G1 PF01567.11 CDI75669.1 - 0.39 8.9 3.1 0.48 8.6 2.2 1.1 1 0 0 1 1 1 0 Hantavirus glycoprotein G1 MMR1 PF08505.5 CDI75669.1 - 0.45 10.5 13.6 0.59 10.1 9.4 1.1 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein Tetraspannin PF00335.15 CDI75669.1 - 0.58 9.3 2.0 0.58 9.4 1.4 1.1 1 0 0 1 1 1 0 Tetraspanin family PAT1 PF09770.4 CDI75669.1 - 0.67 8.1 31.6 0.72 8.0 21.9 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF2052 PF09747.4 CDI75669.1 - 1.8 8.4 16.2 2.7 7.9 11.3 1.2 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) Band_3_cyto PF07565.8 CDI75669.1 - 3 7.2 13.1 3.8 6.9 9.1 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain GPCR_chapero_1 PF11904.3 CDI75669.1 - 6.2 5.8 11.4 7.9 5.5 7.9 1.1 1 0 0 1 1 1 0 GPCR-chaperone BAF1_ABF1 PF04684.8 CDI75670.1 - 0.0054 15.6 33.3 0.0079 15.0 23.1 1.3 1 0 0 1 1 1 1 BAF1 / ABF1 chromatin reorganising factor CDC45 PF02724.9 CDI75670.1 - 0.023 12.7 12.8 0.022 12.7 8.9 1.0 1 0 0 1 1 1 0 CDC45-like protein LELP1 PF15042.1 CDI75670.1 - 0.042 14.0 1.5 0.053 13.7 1.1 1.1 1 0 0 1 1 1 0 Late cornified envelope-like proline-rich protein 1 Spore_coat_CotO PF14153.1 CDI75670.1 - 0.061 12.7 20.2 0.057 12.8 14.0 1.2 1 0 0 1 1 1 0 Spore coat protein CotO Mem_trans PF03547.13 CDI75670.1 - 0.063 11.5 6.7 0.069 11.4 4.6 1.2 1 0 0 1 1 1 0 Membrane transport protein DUF4175 PF13779.1 CDI75670.1 - 0.077 10.6 46.9 0.082 10.5 32.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Ycf1 PF05758.7 CDI75670.1 - 0.27 8.8 14.5 0.26 8.9 10.1 1.0 1 0 0 1 1 1 0 Ycf1 Pex16 PF08610.5 CDI75670.1 - 0.28 10.1 14.2 0.31 9.9 9.8 1.1 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) Cellulose_synt PF03552.9 CDI75670.1 - 0.29 9.3 6.9 0.28 9.4 4.8 1.0 1 0 0 1 1 1 0 Cellulose synthase Dynamin_N PF00350.18 CDI75670.1 - 0.33 10.7 7.4 0.34 10.7 5.1 1.2 1 0 0 1 1 1 0 Dynamin family Gti1_Pac2 PF09729.4 CDI75670.1 - 0.36 10.6 9.1 0.37 10.6 6.3 1.2 1 0 0 1 1 1 0 Gti1/Pac2 family YjgP_YjgQ PF03739.9 CDI75670.1 - 0.39 9.4 8.9 0.48 9.1 6.2 1.1 1 0 0 1 1 1 0 Predicted permease YjgP/YjgQ family Bud13 PF09736.4 CDI75670.1 - 0.79 9.9 23.9 1 9.5 16.5 1.2 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex Band_3_cyto PF07565.8 CDI75670.1 - 0.96 8.9 14.9 1 8.8 10.3 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain AAA_13 PF13166.1 CDI75670.1 - 0.97 7.8 14.0 0.86 7.9 9.7 1.0 1 0 0 1 1 1 0 AAA domain Hid1 PF12722.2 CDI75670.1 - 0.99 6.9 16.5 0.92 7.1 11.4 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein GAGA_bind PF06217.7 CDI75670.1 - 0.99 9.3 13.3 0.91 9.4 9.2 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family ABC2_membrane_2 PF12679.2 CDI75670.1 - 1.3 7.7 4.3 1.5 7.6 3.0 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein FAM60A PF15396.1 CDI75670.1 - 1.4 8.6 11.7 1.4 8.6 8.1 1.2 1 0 0 1 1 1 0 Protein Family FAM60A DUF1510 PF07423.6 CDI75670.1 - 1.4 8.2 19.0 1.6 8.0 13.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DUF4045 PF13254.1 CDI75670.1 - 1.5 7.9 20.0 1.6 7.9 13.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Asp-B-Hydro_N PF05279.6 CDI75670.1 - 1.6 8.5 12.6 1.5 8.5 8.7 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region HGTP_anticodon2 PF12745.2 CDI75670.1 - 1.6 7.8 12.8 1.8 7.6 8.9 1.1 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs PA26 PF04636.8 CDI75670.1 - 1.6 7.3 14.0 1.7 7.2 9.7 1.0 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) SLD3 PF08639.5 CDI75670.1 - 1.7 7.2 18.8 1.5 7.3 13.0 1.1 1 0 0 1 1 1 0 DNA replication regulator SLD3 FemAB PF02388.11 CDI75670.1 - 1.7 7.2 18.5 2 6.9 12.8 1.1 1 0 0 1 1 1 0 FemAB family Tfb4 PF03850.9 CDI75670.1 - 1.9 7.6 10.3 2.2 7.4 7.2 1.2 1 0 0 1 1 1 0 Transcription factor Tfb4 Otopetrin PF03189.8 CDI75670.1 - 1.9 7.3 7.4 1.8 7.4 5.2 1.0 1 0 0 1 1 1 0 Otopetrin Tim54 PF11711.3 CDI75670.1 - 1.9 6.9 13.7 2.3 6.7 9.5 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 FAM176 PF14851.1 CDI75670.1 - 2 8.0 8.7 2.5 7.7 6.0 1.2 1 0 0 1 1 1 0 FAM176 family CDC73 PF05179.9 CDI75670.1 - 2.4 7.4 17.7 2.7 7.2 12.2 1.0 1 0 0 1 1 1 0 RNA pol II accessory factor, Cdc73 family SAPS PF04499.10 CDI75670.1 - 2.4 6.6 12.3 2.3 6.7 8.5 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Fumble PF03630.9 CDI75670.1 - 2.5 6.8 5.0 2.6 6.7 3.5 1.0 1 0 0 1 1 1 0 Fumble Plasmodium_Vir PF05795.6 CDI75670.1 - 2.7 7.1 6.1 2.5 7.1 4.2 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein AUX_IAA PF02309.11 CDI75670.1 - 2.8 7.6 13.8 3 7.5 9.6 1.2 1 0 0 1 1 1 0 AUX/IAA family Atg14 PF10186.4 CDI75670.1 - 2.8 6.7 27.8 3.2 6.5 19.3 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 GOLD_2 PF13897.1 CDI75670.1 - 3 8.0 7.6 4 7.6 5.2 1.2 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking CRF1 PF10380.4 CDI75670.1 - 3.1 8.1 9.8 3.8 7.8 6.8 1.3 1 0 0 1 1 1 0 Transcription factor CRF1 Afi1 PF07792.7 CDI75670.1 - 3.4 7.6 17.3 4.1 7.3 12.0 1.2 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking DUF4613 PF15390.1 CDI75670.1 - 4 5.4 11.3 3.6 5.6 7.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) DUF3492 PF11997.3 CDI75670.1 - 4.1 6.8 10.0 4.1 6.8 6.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3492) Membralin PF09746.4 CDI75670.1 - 4.6 6.1 6.4 4.3 6.2 4.4 1.0 1 0 0 1 1 1 0 Tumour-associated protein Rtf2 PF04641.7 CDI75670.1 - 5.3 6.1 18.5 5.4 6.1 12.8 1.2 1 0 0 1 1 1 0 Rtf2 RING-finger LCD1 PF09798.4 CDI75670.1 - 5.5 4.8 26.8 5.8 4.7 18.5 1.0 1 0 0 1 1 1 0 DNA damage checkpoint protein PIH1 PF08190.7 CDI75670.1 - 6.4 6.1 22.0 6.4 6.1 15.2 1.1 1 0 0 1 1 1 0 pre-RNA processing PIH1/Nop17 CPSF100_C PF13299.1 CDI75670.1 - 6.6 6.8 15.1 8 6.6 10.5 1.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Paramyxo_ncap PF00973.14 CDI75670.1 - 7.3 5.1 13.4 7 5.2 9.3 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein HSP70 PF00012.15 CDI75670.1 - 7.4 4.3 14.3 7.7 4.2 9.9 1.0 1 0 0 1 1 1 0 Hsp70 protein FHIPEP PF00771.15 CDI75670.1 - 7.7 4.7 11.8 8.2 4.6 8.2 1.3 1 0 0 1 1 1 0 FHIPEP family Dehalogenase PF13486.1 CDI75670.1 - 7.9 5.8 12.2 8.2 5.7 8.5 1.1 1 0 0 1 1 1 0 Reductive dehalogenase subunit Draxin PF15550.1 CDI75670.1 - 8 6.0 14.9 11 5.5 10.3 1.3 1 0 0 1 1 1 0 Draxin DUF966 PF06136.8 CDI75670.1 - 8.4 5.6 16.9 10 5.4 11.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) eIF-3_zeta PF05091.7 CDI75670.1 - 8.7 4.8 23.0 9.5 4.7 15.9 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF2828 PF11443.3 CDI75670.1 - 8.7 4.4 12.9 8.2 4.4 8.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) VIT1 PF01988.14 CDI75670.1 - 9.1 5.6 11.7 13 5.1 8.1 1.3 1 0 0 1 1 1 0 VIT family Glyco_transf_15 PF01793.11 CDI75670.1 - 9.6 5.0 16.1 12 4.7 11.2 1.1 1 0 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase PAP1 PF08601.5 CDI75671.1 - 4.7 6.8 13.6 5.8 6.4 9.5 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 Pex14_N PF04695.8 CDI75672.1 - 0.0001 22.3 12.9 0.00012 22.1 9.0 1.1 1 0 0 1 1 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region BAF1_ABF1 PF04684.8 CDI75672.1 - 0.00015 20.7 31.9 0.00022 20.2 22.1 1.2 1 0 0 1 1 1 1 BAF1 / ABF1 chromatin reorganising factor Med15 PF09606.5 CDI75672.1 - 0.0035 15.6 32.7 0.004 15.4 22.6 1.1 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal Suf PF05843.9 CDI75672.1 - 0.0062 16.3 15.2 0.0071 16.1 10.5 1.1 1 0 0 1 1 1 1 Suppressor of forked protein (Suf) DUF3899 PF13038.1 CDI75672.1 - 0.023 14.8 0.3 0.036 14.2 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3899) DUF2370 PF10176.4 CDI75672.1 - 0.024 13.9 2.3 0.031 13.6 1.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) FimP PF09766.4 CDI75672.1 - 0.024 13.7 17.9 0.027 13.5 12.4 1.1 1 0 0 1 1 1 0 Fms-interacting protein PAT1 PF09770.4 CDI75672.1 - 0.03 12.5 24.2 0.03 12.6 16.8 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF4175 PF13779.1 CDI75672.1 - 0.031 12.0 29.7 0.04 11.6 20.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) CDC45 PF02724.9 CDI75672.1 - 0.036 12.1 5.9 0.037 12.0 4.1 1.1 1 0 0 1 1 1 0 CDC45-like protein Spore_coat_CotO PF14153.1 CDI75672.1 - 0.042 13.3 12.0 0.044 13.2 8.3 1.1 1 0 0 1 1 1 0 Spore coat protein CotO Neurensin PF14927.1 CDI75672.1 - 0.042 13.2 0.3 0.072 12.4 0.2 1.4 1 1 0 1 1 1 0 Neurensin RICTOR_N PF14664.1 CDI75672.1 - 0.043 12.4 4.6 0.048 12.2 3.2 1.0 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR, N-term Band_3_cyto PF07565.8 CDI75672.1 - 0.054 13.0 7.7 0.058 12.8 5.4 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Peptidase_S49_N PF08496.5 CDI75672.1 - 0.061 13.1 5.7 0.067 12.9 3.9 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal MFS_Mycoplasma PF07672.8 CDI75672.1 - 0.061 12.4 0.7 0.073 12.2 0.5 1.0 1 0 0 1 1 1 0 Mycoplasma MFS transporter SeqA PF03925.8 CDI75672.1 - 0.065 12.9 9.5 0.079 12.6 6.6 1.1 1 0 0 1 1 1 0 SeqA protein DUF912 PF06024.7 CDI75672.1 - 0.065 13.2 6.4 0.11 12.5 4.4 1.5 1 1 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Peptidase_U57 PF05582.7 CDI75672.1 - 0.071 12.0 5.5 0.076 11.9 3.8 1.1 1 0 0 1 1 1 0 YabG peptidase U57 OmpH PF03938.9 CDI75672.1 - 0.079 12.8 30.0 0.1 12.5 20.8 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) MDFI PF15316.1 CDI75672.1 - 0.08 12.9 2.8 0.086 12.8 1.9 1.1 1 0 0 1 1 1 0 MyoD family inhibitor BTV_NS2 PF04514.7 CDI75672.1 - 0.084 11.7 3.3 0.085 11.7 2.3 1.0 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 DUF4557 PF15101.1 CDI75672.1 - 0.085 12.6 17.6 0.098 12.4 12.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) TMEM51 PF15345.1 CDI75672.1 - 0.092 12.4 9.0 0.1 12.3 6.2 1.3 1 0 0 1 1 1 0 Transmembrane protein 51 Coiled-coil_56 PF09813.4 CDI75672.1 - 0.1 12.6 12.2 0.21 11.6 8.5 1.6 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 56 Glt_symporter PF03616.9 CDI75672.1 - 0.11 10.9 2.9 0.13 10.7 2.0 1.1 1 0 0 1 1 1 0 Sodium/glutamate symporter PBP1_TM PF14812.1 CDI75672.1 - 0.13 12.5 2.2 0.18 12.0 1.5 1.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Baculo_ODV-E27 PF05314.6 CDI75672.1 - 0.13 11.2 3.6 0.16 11.0 2.5 1.0 1 0 0 1 1 1 0 Baculovirus occlusion-derived virus envelope protein EC27 Rtf2 PF04641.7 CDI75672.1 - 0.14 11.3 7.5 0.15 11.2 5.2 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger FLO_LFY PF01698.11 CDI75672.1 - 0.15 10.8 6.0 0.16 10.8 4.2 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein RR_TM4-6 PF06459.7 CDI75672.1 - 0.15 11.8 10.7 0.19 11.6 7.4 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Gti1_Pac2 PF09729.4 CDI75672.1 - 0.16 11.8 4.3 0.17 11.7 3.0 1.1 1 0 0 1 1 1 0 Gti1/Pac2 family CTNNB1_binding PF08347.6 CDI75672.1 - 0.16 12.1 6.5 0.19 11.9 4.5 1.1 1 0 0 1 1 1 0 N-terminal CTNNB1 binding DUF605 PF04652.11 CDI75672.1 - 0.21 10.9 16.0 0.24 10.7 11.1 1.0 1 0 0 1 1 1 0 Vta1 like RNA_pol_Rpc4 PF05132.9 CDI75672.1 - 0.22 11.5 8.8 0.27 11.2 6.1 1.1 1 0 0 1 1 1 0 RNA polymerase III RPC4 AIF_C PF14721.1 CDI75672.1 - 0.22 11.7 7.1 0.31 11.3 4.9 1.2 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term PIH1 PF08190.7 CDI75672.1 - 0.23 10.8 11.8 0.22 10.9 8.2 1.1 1 0 0 1 1 1 0 pre-RNA processing PIH1/Nop17 CPSF100_C PF13299.1 CDI75672.1 - 0.27 11.4 8.1 0.3 11.2 5.6 1.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal RED_N PF07808.8 CDI75672.1 - 0.28 10.3 14.8 0.32 10.1 10.3 1.2 1 0 0 1 1 1 0 RED-like protein N-terminal region DUF3353 PF11833.3 CDI75672.1 - 0.31 10.4 8.6 0.4 10.1 6.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3353) Spc7_N PF15402.1 CDI75672.1 - 0.32 8.9 15.7 0.41 8.5 10.9 1.1 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 7tm_1 PF00001.16 CDI75672.1 - 0.33 10.0 1.2 0.4 9.7 0.8 1.2 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) Ycf1 PF05758.7 CDI75672.1 - 0.39 8.3 7.2 0.37 8.4 5.0 1.0 1 0 0 1 1 1 0 Ycf1 DUF2126 PF09899.4 CDI75672.1 - 0.4 8.6 7.0 0.39 8.7 4.8 1.0 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) Glyco_transf_15 PF01793.11 CDI75672.1 - 0.42 9.5 7.6 0.45 9.4 5.3 1.1 1 0 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase DUF913 PF06025.7 CDI75672.1 - 0.43 9.2 5.7 0.51 9.0 4.0 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DUF2828 PF11443.3 CDI75672.1 - 0.46 8.6 6.2 0.46 8.6 4.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Neur_chan_memb PF02932.11 CDI75672.1 - 0.47 10.3 3.4 0.45 10.3 2.4 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region eIF-3_zeta PF05091.7 CDI75672.1 - 0.56 8.7 11.9 0.59 8.6 8.2 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DHHW PF14286.1 CDI75672.1 - 0.58 9.4 7.3 0.6 9.3 5.1 1.0 1 0 0 1 1 1 0 DHHW protein Herpes_env PF01673.13 CDI75672.1 - 0.59 8.6 8.5 0.67 8.4 5.9 1.0 1 0 0 1 1 1 0 Herpesvirus putative major envelope glycoprotein EIIBC-GUT_N PF03612.9 CDI75672.1 - 0.59 9.7 6.5 0.63 9.6 4.5 1.2 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus CD20 PF04103.10 CDI75672.1 - 0.6 10.0 6.9 1.1 9.2 4.8 1.5 1 1 0 1 1 1 0 CD20-like family OATP PF03137.15 CDI75672.1 - 0.61 8.0 8.0 0.67 7.9 5.6 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family ABC2_membrane_2 PF12679.2 CDI75672.1 - 0.65 8.8 3.0 0.81 8.4 2.1 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein Serinc PF03348.10 CDI75672.1 - 0.65 8.6 9.5 0.74 8.4 6.6 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) Het-C PF07217.6 CDI75672.1 - 0.69 8.0 6.4 0.73 7.9 4.4 1.1 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C DUF4638 PF15472.1 CDI75672.1 - 0.71 9.4 6.4 0.78 9.2 4.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) Sec62 PF03839.11 CDI75672.1 - 0.71 9.2 5.7 0.84 9.0 3.9 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 UPF0233 PF06781.7 CDI75672.1 - 0.76 9.4 3.0 1.2 8.8 2.1 1.6 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0233) DUF775 PF05603.7 CDI75672.1 - 0.88 9.0 10.9 0.93 8.9 7.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF775) Ndc1_Nup PF09531.5 CDI75672.1 - 0.93 7.8 7.4 0.94 7.8 5.1 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF3347 PF11827.3 CDI75672.1 - 1.1 9.2 12.4 1.4 8.8 8.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3347) Bul1_N PF04425.7 CDI75672.1 - 1.1 7.7 8.4 1.1 7.7 5.8 1.0 1 0 0 1 1 1 0 Bul1 N terminus PH_4 PF15404.1 CDI75672.1 - 1.2 8.6 9.8 1.7 8.1 6.8 1.3 1 0 0 1 1 1 0 Pleckstrin homology domain Presenilin PF01080.12 CDI75672.1 - 1.5 7.5 4.7 1.6 7.4 3.3 1.2 1 0 0 1 1 1 0 Presenilin BRF1 PF07741.8 CDI75672.1 - 1.6 9.0 12.5 2.2 8.5 8.7 1.3 1 1 0 1 1 1 0 Brf1-like TBP-binding domain DUF2347 PF09804.4 CDI75672.1 - 1.6 7.9 7.1 2 7.6 4.9 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2347) Zip PF02535.17 CDI75672.1 - 1.9 7.4 7.8 3.1 6.7 5.4 1.3 1 1 0 1 1 1 0 ZIP Zinc transporter DUF3408 PF11888.3 CDI75672.1 - 2 8.3 10.6 2.7 7.9 7.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) RIC3 PF15361.1 CDI75672.1 - 2.1 8.5 14.2 0.21 11.8 6.9 1.5 2 0 0 2 2 1 0 Resistance to inhibitors of cholinesterase homologue 3 Hid1 PF12722.2 CDI75672.1 - 2.1 5.9 11.5 2.2 5.8 8.0 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein FHIPEP PF00771.15 CDI75672.1 - 2.1 6.5 10.6 2.4 6.3 7.4 1.0 1 0 0 1 1 1 0 FHIPEP family FAM60A PF15396.1 CDI75672.1 - 2.1 8.0 9.0 2.9 7.5 6.3 1.1 1 0 0 1 1 1 0 Protein Family FAM60A DDHD PF02862.12 CDI75672.1 - 2.3 7.9 11.5 2.9 7.6 8.0 1.1 1 0 0 1 1 1 0 DDHD domain Paramyxo_ncap PF00973.14 CDI75672.1 - 2.3 6.8 6.8 2.3 6.8 4.7 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein zf-DHHC PF01529.15 CDI75672.1 - 2.7 7.3 5.3 3.4 7.0 3.7 1.4 1 0 0 1 1 1 0 DHHC palmitoyltransferase DUF3675 PF12428.3 CDI75672.1 - 2.8 8.2 8.0 3.8 7.7 5.5 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3675) DUF4366 PF14283.1 CDI75672.1 - 2.8 7.3 9.5 5.4 6.3 6.6 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4366) Tim54 PF11711.3 CDI75672.1 - 3.1 6.3 9.0 3.6 6.0 6.2 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DUF4544 PF15077.1 CDI75672.1 - 3.1 7.2 5.8 3.4 7.1 4.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4544) Peroxin-13_N PF04088.8 CDI75672.1 - 3.4 7.6 7.6 4.3 7.2 5.0 1.3 1 1 0 1 1 1 0 Peroxin 13, N-terminal region G-alpha PF00503.15 CDI75672.1 - 4.3 5.9 11.0 5.1 5.6 7.6 1.1 1 0 0 1 1 1 0 G-protein alpha subunit AUX_IAA PF02309.11 CDI75672.1 - 4.5 6.9 9.7 5.8 6.6 6.8 1.1 1 0 0 1 1 1 0 AUX/IAA family BaxI_1 PF12811.2 CDI75672.1 - 5.1 6.1 7.7 6.5 5.8 5.3 1.3 1 0 0 1 1 1 0 Bax inhibitor 1 like Kei1 PF08552.6 CDI75672.1 - 5.2 6.6 10.3 4.4 6.9 6.7 1.3 1 1 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 SID-1_RNA_chan PF13965.1 CDI75672.1 - 5.7 4.9 6.2 6.4 4.8 4.3 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Pex16 PF08610.5 CDI75672.1 - 6.2 5.7 10.8 6.7 5.5 7.5 1.1 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) LIM_bind PF01803.11 CDI75672.1 - 6.2 5.8 13.8 7.3 5.6 9.6 1.1 1 0 0 1 1 1 0 LIM-domain binding protein LMBR1 PF04791.11 CDI75672.1 - 7.1 5.0 5.9 8 4.9 4.1 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein NifQ PF04891.7 CDI75672.1 - 7.2 6.7 11.5 8.8 6.4 8.0 1.1 1 0 0 1 1 1 0 NifQ FNIP_N PF14636.1 CDI75672.1 - 7.7 7.0 14.8 11 6.4 10.2 1.2 1 0 0 1 1 1 0 Folliculin-interacting protein N-terminus Auxin_inducible PF02519.9 CDI75672.1 - 9.8 6.3 8.2 14 5.8 5.5 1.5 1 1 0 1 1 1 0 Auxin responsive protein CDP-OH_P_transf PF01066.16 CDI75673.1 - 5.1e-12 45.9 11.0 2.8e-11 43.5 7.7 2.3 1 1 0 1 1 1 1 CDP-alcohol phosphatidyltransferase DUF936 PF06075.7 CDI75673.1 - 3.3 6.5 19.8 6.3 5.6 13.7 1.4 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) DUF605 PF04652.11 CDI75673.1 - 7.2 5.9 22.2 11 5.2 15.4 1.2 1 0 0 1 1 1 0 Vta1 like DUF966 PF06136.8 CDI75674.1 - 0.011 15.1 13.3 0.017 14.5 9.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF966) DUF4207 PF13904.1 CDI75674.1 - 0.2 11.0 10.7 0.27 10.5 7.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4207) SR-25 PF10500.4 CDI75674.1 - 0.34 10.3 41.2 1.1 8.6 9.0 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Cyto_ox_2 PF02322.10 CDI75674.1 - 0.7 8.9 17.2 0.85 8.7 11.9 1.1 1 0 0 1 1 1 0 Cytochrome oxidase subunit II DUF1980 PF09323.5 CDI75674.1 - 3.3 7.4 8.2 8.2 6.1 0.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) FA_desaturase PF00487.19 CDI75674.1 - 5.9 6.2 6.5 12 5.2 4.5 1.6 1 1 0 1 1 1 0 Fatty acid desaturase Secretin_N_2 PF07655.8 CDI75674.1 - 7.8 6.9 28.8 7.4 7.0 7.1 2.2 2 0 0 2 2 2 0 Secretin N-terminal domain Metallophos PF00149.23 CDI75675.1 - 0.0004 19.8 0.2 0.00062 19.2 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase IR1-M PF12185.3 CDI75676.1 - 0.17 11.6 1.6 0.23 11.1 1.1 1.3 1 0 0 1 1 1 0 Nup358/RanBP2 E3 ligase domain BSP_II PF05432.6 CDI75676.1 - 0.19 10.9 5.2 0.2 10.8 3.6 1.1 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Patatin PF01734.17 CDI75676.1 - 0.34 10.8 2.0 0.34 10.7 1.4 1.0 1 0 0 1 1 1 0 Patatin-like phospholipase Fibrillarin PF01269.12 CDI75677.1 - 4.5e-103 343.0 0.0 5.1e-103 342.9 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.5 CDI75677.1 - 0.00038 20.0 0.0 0.00058 19.4 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_31 PF13847.1 CDI75677.1 - 0.0018 17.8 0.0 0.0023 17.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CDI75677.1 - 0.011 16.2 0.0 0.018 15.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain DREV PF05219.7 CDI75677.1 - 0.033 13.0 0.0 0.047 12.5 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase PCMT PF01135.14 CDI75677.1 - 0.043 13.3 0.0 0.071 12.6 0.0 1.3 1 1 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Med15 PF09606.5 CDI75678.1 - 0.00026 19.3 79.8 0.00037 18.8 55.3 1.2 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal HI0933_like PF03486.9 CDI75679.1 - 0.015 13.7 11.8 0.015 13.7 8.2 1.0 1 0 0 1 1 1 0 HI0933-like protein Trigger_C PF05698.9 CDI75679.1 - 0.032 14.0 19.1 0.036 13.9 13.3 1.0 1 0 0 1 1 1 0 Bacterial trigger factor protein (TF) C-terminus DUF445 PF04286.7 CDI75679.1 - 0.04 13.4 6.1 0.041 13.4 4.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF445) RE_TdeIII PF09520.5 CDI75679.1 - 0.047 12.9 6.7 0.076 12.2 4.6 1.4 1 1 0 1 1 1 0 Type II restriction endonuclease, TdeIII WASH-7_mid PF14744.1 CDI75679.1 - 0.099 11.4 10.6 0.11 11.3 7.3 1.0 1 0 0 1 1 1 0 WASH complex subunit 7 DUF521 PF04412.8 CDI75679.1 - 0.14 10.7 1.0 0.16 10.4 0.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF521) Ofd1_CTDD PF10637.4 CDI75679.1 - 0.2 10.7 9.9 0.2 10.7 6.9 1.0 1 0 0 1 1 1 0 Oxoglutarate and iron-dependent oxygenase degradation C-term PIG-S PF10510.4 CDI75679.1 - 0.25 9.9 11.4 0.31 9.6 7.9 1.3 1 0 0 1 1 1 0 Phosphatidylinositol-glycan biosynthesis class S protein RHD3 PF05879.7 CDI75679.1 - 0.26 9.1 5.3 0.25 9.2 3.7 1.0 1 0 0 1 1 1 0 Root hair defective 3 GTP-binding protein (RHD3) DUF45 PF01863.12 CDI75679.1 - 0.27 10.9 4.7 0.36 10.5 3.3 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF45 DUF3589 PF12141.3 CDI75679.1 - 0.3 9.2 6.3 0.32 9.1 4.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3589) GlnE PF03710.10 CDI75679.1 - 0.34 10.1 9.8 0.38 9.9 6.8 1.0 1 0 0 1 1 1 0 Glutamate-ammonia ligase adenylyltransferase YkuI_C PF10388.4 CDI75679.1 - 0.36 10.5 12.1 0.42 10.2 8.4 1.1 1 0 0 1 1 1 0 EAL-domain associated signalling protein domain Herpes_UL92 PF03048.9 CDI75679.1 - 0.38 10.3 3.1 0.4 10.2 2.2 1.0 1 0 0 1 1 1 0 UL92 family DUF3987 PF13148.1 CDI75679.1 - 0.55 8.7 5.6 0.56 8.7 3.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) DUF668 PF05003.7 CDI75679.1 - 0.6 10.3 6.3 0.81 9.9 4.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF668) IcmF-related PF06761.7 CDI75679.1 - 0.67 9.1 19.1 0.8 8.9 13.3 1.1 1 0 0 1 1 1 0 Intracellular multiplication and human macrophage-killing Prp18 PF02840.10 CDI75679.1 - 0.79 9.5 8.0 0.87 9.3 5.6 1.1 1 0 0 1 1 1 0 Prp18 domain DUF2939 PF11159.3 CDI75679.1 - 0.8 9.9 21.5 2.8e+02 1.7 14.9 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2939) OmpH PF03938.9 CDI75679.1 - 0.89 9.4 36.0 1.1 9.1 24.9 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Peptidase_C50 PF03568.12 CDI75679.1 - 1 8.0 9.0 1.1 7.8 6.2 1.0 1 0 0 1 1 1 0 Peptidase family C50 Peptidase_S46 PF10459.4 CDI75679.1 - 1 7.7 7.8 1.2 7.4 5.4 1.2 1 0 0 1 1 1 0 Peptidase S46 DUF3417 PF11897.3 CDI75679.1 - 1.1 9.1 7.5 1.3 9.0 5.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3417) MRP-S27 PF10037.4 CDI75679.1 - 1.5 7.6 13.6 1.6 7.5 9.4 1.2 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S27 DDE_Tnp_IS66 PF03050.9 CDI75679.1 - 2 7.5 9.5 2.3 7.3 6.6 1.2 1 0 0 1 1 1 0 Transposase IS66 family FliP PF00813.15 CDI75679.1 - 2.2 7.9 6.1 2.3 7.8 4.2 1.1 1 0 0 1 1 1 0 FliP family DUF4496 PF14908.1 CDI75679.1 - 2.2 8.1 6.7 3 7.7 4.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4496) SPG48 PF14764.1 CDI75679.1 - 2.4 6.5 9.2 2.6 6.4 6.4 1.0 1 0 0 1 1 1 0 AP-5 complex subunit, vesicle trafficking Mmp37 PF09139.6 CDI75679.1 - 2.8 6.8 9.4 3 6.7 6.5 1.0 1 0 0 1 1 1 0 Mitochondrial matrix Mmp37 Spore_II_R PF09551.5 CDI75679.1 - 3 7.8 7.5 4.1 7.4 5.2 1.3 1 0 0 1 1 1 0 Stage II sporulation protein R (spore_II_R) Tweety PF04906.8 CDI75679.1 - 3.9 5.8 11.2 4.5 5.5 7.8 1.1 1 0 0 1 1 1 0 Tweety SICA_alpha PF12887.2 CDI75679.1 - 4.3 7.0 10.2 13 5.4 7.1 1.7 1 1 0 1 1 1 0 SICA extracellular alpha domain DUF972 PF06156.8 CDI75679.1 - 5.4 7.4 14.0 6.3 7.2 9.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF972) Cluap1 PF10234.4 CDI75679.1 - 6.1 5.9 15.7 7.3 5.7 10.9 1.1 1 0 0 1 1 1 0 Clusterin-associated protein-1 DUF940 PF06082.6 CDI75679.1 - 6.6 5.1 7.7 6.9 5.0 5.3 1.0 1 0 0 1 1 1 0 Bacterial putative lipoprotein (DUF940) Exonuc_VII_L PF02601.10 CDI75679.1 - 7.4 5.6 14.9 7.7 5.6 10.3 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit UPF0118 PF01594.11 CDI75679.1 - 7.4 5.4 7.3 8.3 5.2 5.1 1.1 1 0 0 1 1 1 0 Domain of unknown function DUF20 FHIPEP PF00771.15 CDI75679.1 - 8.8 4.5 11.8 9.1 4.4 8.2 1.1 1 0 0 1 1 1 0 FHIPEP family CsoSCA PF08936.5 CDI75679.1 - 8.9 4.5 9.8 9.6 4.4 6.8 1.0 1 0 0 1 1 1 0 Carboxysome Shell Carbonic Anhydrase Tctex-1 PF03645.8 CDI75679.1 - 9 6.2 6.8 13 5.7 4.7 1.3 1 0 0 1 1 1 0 Tctex-1 family DUF2094 PF09867.4 CDI75679.1 - 9.2 6.1 10.4 14 5.5 6.9 1.5 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2094) Mak16 PF04874.9 CDI75680.1 - 8.9e-12 44.9 24.2 8.9e-12 44.9 16.8 3.4 2 1 1 3 3 3 1 Mak16 protein C-terminal region Nop14 PF04147.7 CDI75680.1 - 0.85 7.4 29.4 1.2 7.0 20.4 1.2 1 0 0 1 1 1 0 Nop14-like family BNIP2 PF12496.3 CDI75680.1 - 9.9 6.3 13.2 16 5.6 9.0 1.6 1 1 0 1 1 1 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 BT1 PF03092.11 CDI75682.1 - 1.1e-65 222.1 20.3 2.9e-65 220.6 14.1 1.6 1 1 0 1 1 1 1 BT1 family MFS_1 PF07690.11 CDI75682.1 - 0.0013 17.5 45.4 0.005 15.6 6.7 3.9 2 2 2 4 4 4 3 Major Facilitator Superfamily Suf PF05843.9 CDI75683.1 - 0.0027 17.4 7.4 0.0027 17.4 5.1 3.2 2 1 1 3 3 3 1 Suppressor of forked protein (Suf) PAT1 PF09770.4 CDI75683.1 - 0.014 13.6 33.5 0.041 12.1 3.5 2.3 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 G-patch_2 PF12656.2 CDI75683.1 - 0.28 11.0 3.2 1.6 8.6 0.5 2.8 2 0 0 2 2 2 0 DExH-box splicing factor binding site DUF3853 PF12964.2 CDI75683.1 - 2.1 8.1 5.0 23 4.8 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3853) Med15 PF09606.5 CDI75683.1 - 4.9 5.2 58.9 0.0052 15.0 9.3 2.8 3 0 0 3 3 3 0 ARC105 or Med15 subunit of Mediator complex non-fungal BatD PF13584.1 CDI75684.1 - 0.00011 20.9 6.7 0.00011 20.9 4.7 3.0 1 1 2 3 3 2 2 Oxygen tolerance eIF-3c_N PF05470.7 CDI75684.1 - 0.00019 19.6 0.0 0.00019 19.6 0.0 2.5 1 1 1 2 2 1 1 Eukaryotic translation initiation factor 3 subunit 8 N-terminus DUF912 PF06024.7 CDI75684.1 - 0.00037 20.4 2.4 0.00037 20.4 1.7 4.8 3 2 1 4 4 3 1 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF3169 PF11368.3 CDI75684.1 - 0.0011 18.2 0.4 0.0011 18.2 0.3 2.8 2 2 1 3 3 1 1 Protein of unknown function (DUF3169) DUF2207 PF09972.4 CDI75684.1 - 0.002 16.8 2.2 0.002 16.8 1.5 2.8 1 1 1 3 3 2 1 Predicted membrane protein (DUF2207) GRP PF07172.6 CDI75684.1 - 0.0021 18.4 0.5 0.0021 18.4 0.4 5.0 4 1 0 4 4 2 1 Glycine rich protein family V_ATPase_I PF01496.14 CDI75684.1 - 0.0025 15.7 6.3 0.0025 15.7 4.4 2.9 1 1 2 3 3 1 1 V-type ATPase 116kDa subunit family Peptidase_M56 PF05569.6 CDI75684.1 - 0.0031 16.5 4.7 0.0031 16.5 3.3 1.6 1 1 0 1 1 1 1 BlaR1 peptidase M56 MIP-T3 PF10243.4 CDI75684.1 - 0.0037 15.8 81.7 0.042 12.3 6.4 2.6 2 1 0 2 2 2 2 Microtubule-binding protein MIP-T3 TMEM154 PF15102.1 CDI75684.1 - 0.0069 16.1 12.7 0.0069 16.1 8.8 4.4 3 2 0 3 3 1 1 TMEM154 protein family Tmemb_9 PF05434.6 CDI75684.1 - 0.0069 16.1 3.7 0.0069 16.1 2.6 3.4 2 1 1 3 3 1 1 TMEM9 EphA2_TM PF14575.1 CDI75684.1 - 0.0086 16.4 0.2 0.0086 16.4 0.1 5.7 2 1 1 3 3 1 1 Ephrin type-A receptor 2 transmembrane domain RskA PF10099.4 CDI75684.1 - 0.0097 15.6 2.6 0.025 14.2 1.7 1.8 1 1 1 2 2 2 1 Anti-sigma-K factor rskA FimP PF09766.4 CDI75684.1 - 0.015 14.4 7.0 0.015 14.4 4.9 4.7 2 1 1 4 4 2 0 Fms-interacting protein DUF3357 PF11837.3 CDI75684.1 - 0.017 14.9 1.1 0.017 14.9 0.8 4.3 1 1 3 4 4 4 0 Domain of unknown function (DUF3357) CD20 PF04103.10 CDI75684.1 - 0.02 14.8 2.6 0.02 14.8 1.8 2.9 2 2 1 3 3 2 0 CD20-like family Pex14_N PF04695.8 CDI75684.1 - 0.022 14.7 6.5 0.022 14.7 4.5 3.4 2 1 1 3 3 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Scs3p PF10261.4 CDI75684.1 - 0.023 13.7 0.6 0.023 13.7 0.4 3.0 1 1 2 3 3 1 0 Inositol phospholipid synthesis and fat-storage-inducing TM Pex24p PF06398.6 CDI75684.1 - 0.024 13.4 0.9 0.024 13.4 0.6 3.3 1 1 2 3 3 2 0 Integral peroxisomal membrane peroxin DUF1510 PF07423.6 CDI75684.1 - 0.03 13.7 0.3 0.03 13.7 0.2 4.0 2 1 2 4 4 3 0 Protein of unknown function (DUF1510) UPF0182 PF03699.8 CDI75684.1 - 0.058 11.3 2.9 0.078 10.8 2.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0182) RELT PF12606.3 CDI75684.1 - 0.061 12.4 0.0 0.061 12.4 0.0 5.9 4 1 0 4 4 2 0 Tumour necrosis factor receptor superfamily member 19 DUF3899 PF13038.1 CDI75684.1 - 0.061 13.4 0.2 0.061 13.4 0.2 5.4 3 1 1 4 4 3 0 Domain of unknown function (DUF3899) HemY_N PF07219.8 CDI75684.1 - 0.1 12.1 0.0 0.1 12.1 0.0 2.7 3 0 0 3 3 3 0 HemY protein N-terminus Herpes_LMP1 PF05297.6 CDI75684.1 - 0.11 11.3 0.1 0.16 10.8 0.1 1.4 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) NicO PF03824.11 CDI75684.1 - 0.12 11.6 2.8 0.19 11.0 1.9 1.3 1 0 0 1 1 1 0 High-affinity nickel-transport protein MAPEG PF01124.13 CDI75684.1 - 0.15 11.6 0.0 0.15 11.6 0.0 2.1 2 0 0 2 2 1 0 MAPEG family Herpes_gE PF02480.11 CDI75684.1 - 0.18 10.0 11.2 1.6 6.8 7.6 2.3 1 1 0 1 1 1 0 Alphaherpesvirus glycoprotein E TAS2R PF05296.8 CDI75684.1 - 0.23 10.3 7.0 0.33 9.7 4.8 1.2 1 0 0 1 1 1 0 Mammalian taste receptor protein (TAS2R) Gemini_mov PF01708.11 CDI75684.1 - 0.28 10.7 2.3 0.74 9.3 1.5 1.9 1 1 1 2 2 2 0 Geminivirus putative movement protein PBP1_TM PF14812.1 CDI75684.1 - 0.37 11.1 0.0 0.37 11.1 0.0 4.7 4 1 0 4 4 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal TRC8_N PF13705.1 CDI75684.1 - 0.55 8.7 5.2 0.74 8.3 3.6 1.1 1 0 0 1 1 1 0 TRC8 N-terminal domain ATP-synt_8 PF00895.15 CDI75684.1 - 0.61 10.3 0.0 0.61 10.3 0.0 5.3 4 1 0 4 4 3 0 ATP synthase protein 8 DUF4064 PF13273.1 CDI75684.1 - 1.5 8.9 8.2 0.39 10.8 0.6 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF4064) DUF4448 PF14610.1 CDI75684.1 - 2.7 7.4 0.0 2.7 7.4 0.0 4.5 3 2 1 4 4 2 0 Protein of unknown function (DUF4448) DUF936 PF06075.7 CDI75684.1 - 5.1 5.8 37.3 4.9 5.9 24.9 1.6 1 1 0 1 1 1 0 Plant protein of unknown function (DUF936) HGTP_anticodon2 PF12745.2 CDI75685.1 - 0.0088 15.2 8.6 0.01 14.9 5.9 1.0 1 0 0 1 1 1 1 Anticodon binding domain of tRNAs RskA PF10099.4 CDI75685.1 - 0.021 14.5 1.5 0.025 14.3 1.0 1.1 1 0 0 1 1 1 0 Anti-sigma-K factor rskA Peptidase_S49_N PF08496.5 CDI75685.1 - 0.095 12.4 14.0 0.11 12.2 9.7 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Chordopox_G3 PF06129.7 CDI75685.1 - 0.2 11.8 2.2 0.31 11.2 1.5 1.4 1 1 0 1 1 1 0 Chordopoxvirus G3 protein RR_TM4-6 PF06459.7 CDI75685.1 - 0.23 11.3 10.0 0.23 11.3 6.9 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Serinc PF03348.10 CDI75685.1 - 0.24 10.0 10.5 0.27 9.9 7.3 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) ABC2_membrane_2 PF12679.2 CDI75685.1 - 0.26 10.1 2.8 0.37 9.6 2.0 1.4 1 1 0 1 1 1 0 ABC-2 family transporter protein KASH PF10541.4 CDI75685.1 - 0.31 10.8 3.8 0.56 10.0 2.7 1.4 1 0 0 1 1 1 0 Nuclear envelope localisation domain Dynamin_N PF00350.18 CDI75685.1 - 0.34 10.7 6.1 0.42 10.4 4.2 1.1 1 0 0 1 1 1 0 Dynamin family GDE_N PF12439.3 CDI75685.1 - 0.54 9.4 7.8 0.66 9.1 5.4 1.1 1 0 0 1 1 1 0 Glycogen debranching enzyme N terminal Pex14_N PF04695.8 CDI75685.1 - 0.58 10.2 15.3 0.83 9.7 10.6 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region FimP PF09766.4 CDI75685.1 - 0.61 9.0 22.7 0.7 8.8 15.7 1.1 1 0 0 1 1 1 0 Fms-interacting protein Ycf1 PF05758.7 CDI75685.1 - 0.63 7.6 15.0 0.71 7.5 10.4 1.0 1 0 0 1 1 1 0 Ycf1 DDHD PF02862.12 CDI75685.1 - 0.65 9.7 11.9 0.76 9.5 8.2 1.1 1 0 0 1 1 1 0 DDHD domain YfhO PF09586.5 CDI75685.1 - 0.72 7.7 9.3 0.77 7.6 6.4 1.0 1 0 0 1 1 1 0 Bacterial membrane protein YfhO FLO_LFY PF01698.11 CDI75685.1 - 0.74 8.5 10.4 0.75 8.5 7.2 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein Neur_chan_memb PF02932.11 CDI75685.1 - 0.79 9.5 6.7 0.91 9.3 4.7 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Ctr PF04145.10 CDI75685.1 - 0.79 9.7 5.4 1 9.3 3.8 1.3 1 0 0 1 1 1 0 Ctr copper transporter family PAT1 PF09770.4 CDI75685.1 - 0.87 7.7 29.9 0.87 7.7 20.7 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 BORG_CEP PF14957.1 CDI75685.1 - 0.89 10.4 9.0 1 10.3 6.2 1.1 1 0 0 1 1 1 0 Cdc42 effector DUF1980 PF09323.5 CDI75685.1 - 0.97 9.1 9.6 1.2 8.8 6.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) DUF3260 PF11658.3 CDI75685.1 - 1 7.4 10.5 1.2 7.2 7.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3260) Presenilin PF01080.12 CDI75685.1 - 1.1 8.0 4.3 1.3 7.8 3.0 1.2 1 0 0 1 1 1 0 Presenilin DUF4638 PF15472.1 CDI75685.1 - 1.1 8.7 13.3 1.3 8.5 9.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) YABBY PF04690.8 CDI75685.1 - 1.1 9.4 9.3 1.4 9.1 6.5 1.1 1 0 0 1 1 1 0 YABBY protein FMN_dh PF01070.13 CDI75685.1 - 1.3 7.7 7.0 1.4 7.6 4.9 1.0 1 0 0 1 1 1 0 FMN-dependent dehydrogenase Endonuc_Holl PF10107.4 CDI75685.1 - 1.6 8.4 13.3 2.1 8.0 9.2 1.3 1 0 0 1 1 1 0 Endonuclease related to archaeal Holliday junction resolvase Folate_carrier PF01770.13 CDI75685.1 - 1.7 7.0 7.6 1.7 7.0 5.3 1.1 1 0 0 1 1 1 0 Reduced folate carrier SID-1_RNA_chan PF13965.1 CDI75685.1 - 1.8 6.6 9.3 2 6.4 6.4 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Hid1 PF12722.2 CDI75685.1 - 1.9 6.0 13.1 2.1 5.9 9.1 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Asp-B-Hydro_N PF05279.6 CDI75685.1 - 2.2 8.0 11.5 2.7 7.7 7.9 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Sec62 PF03839.11 CDI75685.1 - 2.2 7.6 9.9 2.6 7.4 6.9 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 Suf PF05843.9 CDI75685.1 - 2.3 7.8 15.2 2.9 7.5 10.5 1.4 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Shisa PF13908.1 CDI75685.1 - 2.4 8.2 10.3 3.1 7.9 7.2 1.2 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator RNA_pol_Rpb1_5 PF04998.12 CDI75685.1 - 2.6 7.2 8.1 2.8 7.1 5.6 1.0 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 Scs3p PF10261.4 CDI75685.1 - 2.7 6.9 5.8 5 6.1 4.0 1.4 1 1 0 1 1 1 0 Inositol phospholipid synthesis and fat-storage-inducing TM DUF4446 PF14584.1 CDI75685.1 - 3 7.6 11.3 4.1 7.2 7.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) FliP PF00813.15 CDI75685.1 - 3.1 7.4 12.7 3.7 7.2 8.8 1.1 1 0 0 1 1 1 0 FliP family Gag_spuma PF03276.9 CDI75685.1 - 3.6 5.8 22.9 3.4 5.8 15.9 1.0 1 0 0 1 1 1 0 Spumavirus gag protein Band_3_cyto PF07565.8 CDI75685.1 - 3.6 7.0 18.2 4.1 6.8 12.6 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain DUF2072 PF09845.4 CDI75685.1 - 3.6 7.5 8.4 4.4 7.2 5.8 1.2 1 0 0 1 1 1 0 Zn-ribbon containing protein (DUF2072) Mem_trans PF03547.13 CDI75685.1 - 4.2 5.5 5.2 4.5 5.4 3.6 1.1 1 0 0 1 1 1 0 Membrane transport protein FAM60A PF15396.1 CDI75685.1 - 4.3 7.0 10.1 5.3 6.7 7.0 1.1 1 0 0 1 1 1 0 Protein Family FAM60A DUF1764 PF08576.5 CDI75685.1 - 4.6 8.0 15.0 7 7.4 10.4 1.4 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) Dehydrin PF00257.14 CDI75685.1 - 4.9 7.4 15.2 7.6 6.8 10.6 1.2 1 0 0 1 1 1 0 Dehydrin Paramyxo_ncap PF00973.14 CDI75685.1 - 5.4 5.5 11.3 5.7 5.5 7.8 1.0 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Bud13 PF09736.4 CDI75685.1 - 5.8 7.1 19.4 8.1 6.6 13.4 1.3 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex Gti1_Pac2 PF09729.4 CDI75685.1 - 7.1 6.4 10.6 8.7 6.1 7.3 1.2 1 0 0 1 1 1 0 Gti1/Pac2 family AIF_C PF14721.1 CDI75685.1 - 9.3 6.5 10.7 13 6.0 7.4 1.2 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Hom_end_hint PF05203.11 CDI75685.1 - 9.5 5.8 9.5 12 5.5 6.6 1.1 1 0 0 1 1 1 0 Hom_end-associated Hint SR-25 PF10500.4 CDI75686.1 - 0.00033 20.2 9.6 0.00033 20.2 6.7 5.1 3 2 0 3 3 3 1 Nuclear RNA-splicing-associated protein AAA_23 PF13476.1 CDI75686.1 - 5.2 7.3 28.2 1.3 9.3 2.2 3.1 3 0 0 3 3 3 0 AAA domain DUF755 PF05501.6 CDI75688.1 - 0.0046 17.0 20.6 0.0046 17.0 14.3 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF755) RAB3GAP2_N PF14655.1 CDI75688.1 - 0.16 10.9 10.3 0.26 10.2 7.2 1.3 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus DUF2215 PF10225.4 CDI75688.1 - 0.34 10.3 4.2 0.51 9.7 2.9 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) IMCp PF12314.3 CDI75689.1 - 7.6e-27 93.2 52.1 2.1e-25 88.6 25.5 2.7 2 1 2 4 4 4 3 Inner membrane complex protein IMCp PF12314.3 CDI75690.1 - 8.6e-19 67.4 51.9 3e-14 52.9 19.1 2.1 1 1 1 2 2 2 2 Inner membrane complex protein CDC45 PF02724.9 CDI75691.1 - 9.2 4.1 14.4 18 3.1 10.0 1.4 1 0 0 1 1 1 0 CDC45-like protein DUF3373 PF11853.3 CDI75692.1 - 0.21 10.0 9.7 0.37 9.2 6.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) Raftlin PF15250.1 CDI75692.1 - 0.21 10.0 26.0 0.019 13.5 10.8 2.1 2 0 0 2 2 2 0 Raftlin Cwf_Cwc_15 PF04889.7 CDI75692.1 - 0.46 10.1 32.0 1 9.0 1.2 2.4 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein DUF966 PF06136.8 CDI75692.1 - 3.9 6.8 27.2 2.8 7.2 1.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF966) LcrR PF09621.5 CDI75693.1 - 0.017 14.4 0.0 0.038 13.2 0.0 1.6 1 0 0 1 1 1 0 Type III secretion system regulator (LcrR) ERM PF00769.14 CDI75694.1 - 0.015 14.8 11.3 0.026 14.0 7.8 1.3 1 0 0 1 1 1 0 Ezrin/radixin/moesin family Arfaptin PF06456.8 CDI75694.1 - 0.11 11.7 2.6 2.1 7.6 1.3 2.1 1 1 1 2 2 2 0 Arfaptin-like domain Corona_nucleoca PF00937.13 CDI75695.1 - 1 8.2 34.9 1 8.2 24.2 1.0 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein CDK2AP PF09806.4 CDI75695.1 - 1.1 9.4 20.7 1.3 9.2 14.4 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein Spt20 PF12090.3 CDI75695.1 - 1.9 7.7 10.4 2.1 7.6 7.2 1.2 1 0 0 1 1 1 0 Spt20 family Med19 PF10278.4 CDI75695.1 - 4.6 6.8 12.6 4.8 6.8 8.7 1.1 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 Period_C PF12114.3 CDI75695.1 - 4.8 6.7 28.2 5 6.6 19.5 1.0 1 0 0 1 1 1 0 Period protein 2/3C-terminal region CAF-1_p150 PF11600.3 CDI75695.1 - 6.4 6.0 30.3 7 5.9 21.0 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal SprA-related PF12118.3 CDI75695.1 - 7.6 5.7 25.9 8.3 5.6 18.0 1.1 1 0 0 1 1 1 0 SprA-related family Spore_coat_CotO PF14153.1 CDI75695.1 - 8.1 5.8 20.4 8.7 5.7 14.1 1.0 1 0 0 1 1 1 0 Spore coat protein CotO DUF3984 PF13136.1 CDI75695.1 - 10 5.2 29.6 10 5.2 20.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3984) PIG-U PF06728.8 CDI75696.1 - 0.028 13.2 3.8 0.55 9.0 0.1 3.2 1 1 2 3 3 3 0 GPI transamidase subunit PIG-U Glyco_hydro_1 PF00232.13 CDI75696.1 - 8.9 4.3 9.8 0.69 8.0 2.6 2.1 2 0 0 2 2 2 0 Glycosyl hydrolase family 1 Conotoxin PF02950.12 CDI75697.1 - 0.0039 17.9 3.6 0.0039 17.9 2.5 6.9 4 1 3 7 7 7 1 Conotoxin FimP PF09766.4 CDI75697.1 - 0.0041 16.2 8.1 0.0041 16.2 5.6 5.3 4 1 1 5 5 5 1 Fms-interacting protein DUF1510 PF07423.6 CDI75697.1 - 0.016 14.6 0.7 0.016 14.6 0.5 4.4 3 1 1 4 4 4 0 Protein of unknown function (DUF1510) GRP PF07172.6 CDI75697.1 - 0.017 15.5 0.7 0.017 15.5 0.5 5.6 4 1 0 4 4 4 0 Glycine rich protein family SIT PF15330.1 CDI75697.1 - 0.021 14.9 4.4 0.021 14.9 3.0 6.8 6 1 1 7 7 7 0 SHP2-interacting transmembrane adaptor protein, SIT EphA2_TM PF14575.1 CDI75697.1 - 0.053 13.9 0.2 0.053 13.9 0.1 6.4 4 1 0 4 4 4 0 Ephrin type-A receptor 2 transmembrane domain DUF4512 PF14975.1 CDI75697.1 - 0.11 13.3 0.1 0.11 13.3 0.0 5.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4512) RAP1 PF07218.6 CDI75697.1 - 1.4 6.9 19.0 2.1 6.3 13.2 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) RasGEF_N PF00618.15 CDI75697.1 - 3.3 7.8 0.0 3.3 7.8 0.0 5.6 2 1 1 3 3 3 0 RasGEF N-terminal motif TRC8_N PF13705.1 CDI75697.1 - 3.9 5.9 13.6 1.4 7.4 5.8 2.2 2 0 0 2 2 2 0 TRC8 N-terminal domain Cohesin_HEAT PF12765.2 CDI75699.1 - 0.033 14.1 2.7 3.7 7.6 0.1 3.2 2 0 0 2 2 2 0 HEAT repeat associated with sister chromatid cohesion Med15 PF09606.5 CDI75700.1 - 0.13 10.4 72.0 0.15 10.2 49.9 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF1675 PF07897.6 CDI75700.1 - 0.73 9.6 37.2 0.84 9.4 25.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) YcaO PF02624.11 CDI75700.1 - 2.5 7.5 13.4 3.1 7.2 9.3 1.0 1 0 0 1 1 1 0 YcaO-like family Ycf1 PF05758.7 CDI75700.1 - 7.1 4.1 36.4 8.6 3.9 25.2 1.1 1 0 0 1 1 1 0 Ycf1 RNA_pol_Rpb1_5 PF04998.12 CDI75700.1 - 7.3 5.7 20.4 10 5.2 14.1 1.4 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 FLO_LFY PF01698.11 CDI75700.1 - 8.8 5.0 37.0 12 4.5 25.7 1.2 1 0 0 1 1 1 0 Floricaula / Leafy protein Hid1 PF12722.2 CDI75700.1 - 8.8 3.8 36.0 12 3.4 25.0 1.3 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SR-25 PF10500.4 CDI75701.1 - 6.4e-05 22.5 24.2 6.4e-05 22.5 16.8 4.5 3 1 1 4 4 4 2 Nuclear RNA-splicing-associated protein RskA PF10099.4 CDI75701.1 - 0.0073 16.0 15.1 0.0073 16.0 10.5 5.6 3 2 2 5 5 5 1 Anti-sigma-K factor rskA Peptidase_S49_N PF08496.5 CDI75701.1 - 0.0089 15.8 0.5 0.0089 15.8 0.3 4.7 4 1 1 5 5 5 3 Peptidase family S49 N-terminal Herpes_UL87 PF03043.9 CDI75701.1 - 0.023 13.0 0.0 0.023 13.0 0.0 2.6 1 1 1 2 2 2 0 Herpesvirus UL87 family Macoilin PF09726.4 CDI75701.1 - 0.79 7.9 41.9 0.011 14.0 21.4 2.3 2 0 0 2 2 2 0 Transmembrane protein SOBP PF15279.1 CDI75702.1 - 0.28 11.5 21.8 0.36 11.1 15.1 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein PAT1 PF09770.4 CDI75702.1 - 0.5 8.5 69.3 0.6 8.2 48.0 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Med15 PF09606.5 CDI75702.1 - 3.5 5.6 84.3 4.9 5.2 58.4 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal PLRV_ORF5 PF01690.12 CDI75702.1 - 8 5.4 26.1 10 5.1 18.1 1.2 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein DUF940 PF06082.6 CDI75703.1 - 0.14 10.6 6.0 0.29 9.6 4.2 1.6 1 1 0 1 1 1 0 Bacterial putative lipoprotein (DUF940) AAA_23 PF13476.1 CDI75703.1 - 0.14 12.4 8.1 0.34 11.2 1.5 2.2 2 0 0 2 2 2 0 AAA domain RAP1 PF07218.6 CDI75703.1 - 0.31 9.0 1.2 0.32 9.0 0.8 1.4 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Mito_fiss_reg PF05308.6 CDI75703.1 - 2.1 7.6 12.5 0.065 12.6 4.0 1.9 2 0 0 2 2 2 0 Mitochondrial fission regulator Kelch_1 PF01344.20 CDI75704.1 - 2.3e-18 65.4 0.1 3.3e-09 36.1 0.0 2.8 3 0 0 3 3 3 2 Kelch motif Kelch_6 PF13964.1 CDI75704.1 - 3.1e-17 61.9 0.1 2.5e-11 43.2 0.1 2.1 1 1 1 2 2 2 2 Kelch motif Kelch_4 PF13418.1 CDI75704.1 - 3.3e-16 58.7 0.7 3.9e-10 39.3 0.1 2.9 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_3 PF13415.1 CDI75704.1 - 4.5e-15 55.3 0.3 1.9e-08 34.2 0.2 2.1 2 0 0 2 2 2 2 Galactose oxidase, central domain Kelch_2 PF07646.10 CDI75704.1 - 1.9e-08 33.7 0.1 0.0015 18.1 0.1 2.4 2 0 0 2 2 2 2 Kelch motif Kelch_5 PF13854.1 CDI75704.1 - 2.1e-05 24.3 0.1 0.00038 20.3 0.0 2.5 3 0 0 3 3 3 1 Kelch motif DUF1668 PF07893.8 CDI75704.1 - 0.042 12.9 0.0 0.043 12.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1668) CN_hydrolase PF00795.17 CDI75705.1 - 3.4e-08 33.0 17.7 7.8e-05 22.0 4.0 2.3 2 0 0 2 2 2 2 Carbon-nitrogen hydrolase Med15 PF09606.5 CDI75706.1 - 0.23 9.6 155.6 0.0057 14.9 36.4 4.1 4 0 0 4 4 4 0 ARC105 or Med15 subunit of Mediator complex non-fungal Activator_LAG-3 PF11498.3 CDI75707.1 - 0.0033 16.2 6.0 0.0033 16.2 4.1 6.9 6 2 1 7 7 7 3 Transcriptional activator LAG-3 Dehydrin PF00257.14 CDI75708.1 - 0.28 11.4 0.0 0.28 11.4 0.0 5.3 5 1 0 6 6 6 0 Dehydrin zf-DHHC PF01529.15 CDI75708.1 - 0.82 9.0 12.7 1.3 8.4 0.0 3.4 3 0 0 3 3 3 0 DHHC palmitoyltransferase FCP1_C PF09309.5 CDI75709.1 - 0.036 13.3 9.9 0.046 13.0 6.8 1.1 1 0 0 1 1 1 0 FCP1, C-terminal Plasmodium_Vir PF05795.6 CDI75709.1 - 0.53 9.4 5.8 0.66 9.1 4.0 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein DUF3403 PF11883.3 CDI75709.1 - 0.88 9.8 7.6 1.6 9.0 1.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3403) FAM220 PF15487.1 CDI75709.1 - 2.1 7.6 17.5 2.4 7.4 12.1 1.1 1 0 0 1 1 1 0 FAM220 family Rifin_STEVOR PF02009.11 CDI75709.1 - 5.2 6.6 11.4 6.2 6.3 7.9 1.1 1 0 0 1 1 1 0 Rifin/stevor family IncA PF04156.9 CDI75710.1 - 0.013 15.0 12.7 0.013 15.0 8.8 2.6 1 1 0 2 2 2 0 IncA protein Med15 PF09606.5 CDI75710.1 - 0.035 12.3 74.4 0.05 11.7 51.6 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal PLRV_ORF5 PF01690.12 CDI75710.1 - 0.15 11.1 13.1 0.21 10.6 9.1 1.2 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Herpes_UL87 PF03043.9 CDI75710.1 - 0.21 9.9 8.5 0.25 9.7 5.9 1.1 1 0 0 1 1 1 0 Herpesvirus UL87 family COPI_assoc PF08507.5 CDI75710.1 - 0.6 9.7 0.0 0.6 9.7 0.0 1.9 2 1 0 2 2 2 0 COPI associated protein Ribosomal_60s PF00428.14 CDI75710.1 - 1 9.8 18.7 0.25 11.7 5.1 2.4 2 0 0 2 2 2 0 60s Acidic ribosomal protein FAM60A PF15396.1 CDI75710.1 - 3 7.5 11.2 12 5.6 0.1 2.2 2 0 0 2 2 2 0 Protein Family FAM60A RskA PF10099.4 CDI75710.1 - 7.1 6.3 32.7 0.02 14.6 2.7 3.1 1 1 2 3 3 3 0 Anti-sigma-K factor rskA Clr2 PF10383.4 CDI75710.1 - 9.3 6.2 13.2 8.4 6.3 8.2 1.6 1 1 0 1 1 1 0 Transcription-silencing protein Clr2 DUF3626 PF12294.3 CDI75712.1 - 0.00052 19.1 0.6 0.053 12.5 0.0 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF3626) Pkinase PF00069.20 CDI75713.1 - 1.8e-36 125.6 0.0 2e-36 125.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDI75713.1 - 3.3e-16 59.1 0.0 4.1e-16 58.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 CDI75713.1 - 0.048 12.4 0.1 0.074 11.8 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase DUF839 PF05787.8 CDI75714.1 - 0.11 11.3 0.0 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF839) DUF4349 PF14257.1 CDI75714.1 - 1.9 7.6 4.6 1.9 7.6 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4349) DUF948 PF06103.6 CDI75717.1 - 0.19 11.6 2.2 1.5 8.7 0.1 3.6 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF1664 PF07889.7 CDI75717.1 - 1.1 9.0 6.1 0.7 9.7 1.1 2.9 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) TBPIP PF07106.8 CDI75717.1 - 4 6.9 11.2 1.2 8.6 3.1 2.9 2 1 1 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) FERM_M PF00373.13 CDI75721.1 - 2.1 8.5 8.9 0.097 12.8 1.0 2.5 2 2 0 2 2 2 0 FERM central domain DUF1825 PF08855.5 CDI75724.1 - 0.014 15.4 3.3 0.014 15.4 2.3 3.0 3 1 1 4 4 4 0 Domain of unknown function (DUF1825) IQ PF00612.22 CDI75724.1 - 0.019 14.6 0.2 0.06 13.0 0.1 2.0 1 0 0 1 1 1 0 IQ calmodulin-binding motif zf-HC2 PF13490.1 CDI75724.1 - 0.29 11.1 3.4 0.49 10.3 1.0 2.5 2 0 0 2 2 2 0 Putative zinc-finger IZUMO PF15005.1 CDI75724.1 - 2.1 8.3 8.5 0.22 11.5 0.4 2.7 1 1 1 2 2 2 0 Izumo sperm-egg fusion Imm35 PF15581.1 CDI75724.1 - 2.6 8.1 4.9 0.66 10.0 0.1 2.5 3 0 0 3 3 3 0 Immunity protein 35 AAA_13 PF13166.1 CDI75724.1 - 9.8 4.4 33.7 1.6 7.1 19.8 2.0 1 1 1 2 2 2 0 AAA domain Dpy-30 PF05186.8 CDI75725.1 - 6.4e-08 31.9 0.0 1.4e-07 30.8 0.0 1.5 1 0 0 1 1 1 1 Dpy-30 motif DUF2215 PF10225.4 CDI75725.1 - 0.18 11.2 3.2 0.32 10.4 2.2 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) DUF1918 PF08940.6 CDI75726.1 - 0.11 11.8 0.2 0.45 9.9 0.0 2.1 3 0 0 3 3 3 0 Domain of unknown function (DUF1918) Trypsin_2 PF13365.1 CDI75727.1 - 2.2e-15 56.6 0.0 3.8e-15 55.9 0.0 1.4 1 0 0 1 1 1 1 Trypsin-like peptidase domain PDZ PF00595.19 CDI75727.1 - 5.3e-05 23.3 0.0 0.00011 22.3 0.0 1.6 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 CDI75727.1 - 9.7e-05 22.1 0.0 0.00018 21.3 0.0 1.4 1 0 0 1 1 1 1 PDZ domain Peptidase_S7 PF00949.16 CDI75727.1 - 0.049 13.0 0.0 0.092 12.1 0.0 1.4 1 0 0 1 1 1 0 Peptidase S7, Flavivirus NS3 serine protease Peptidase_S29 PF02907.10 CDI75727.1 - 0.06 12.8 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 Hepatitis C virus NS3 protease Trypsin PF00089.21 CDI75727.1 - 0.071 12.6 0.0 0.33 10.5 0.0 2.0 1 1 0 1 1 1 0 Trypsin EF-hand_8 PF13833.1 CDI75728.1 - 0.015 14.9 0.0 2.7 7.6 0.0 3.2 3 0 0 3 3 3 0 EF-hand domain pair Lamprin PF06403.6 CDI75729.1 - 0.049 13.3 0.7 0.074 12.7 0.5 1.3 1 0 0 1 1 1 0 Lamprin Ribosomal_S3Ae PF01015.13 CDI75730.1 - 8.1e-81 270.0 0.6 9.8e-81 269.7 0.4 1.1 1 0 0 1 1 1 1 Ribosomal S3Ae family Kelch_3 PF13415.1 CDI75731.1 - 1.5e-20 72.7 5.6 4.2e-07 29.9 0.1 5.2 4 1 0 4 4 4 3 Galactose oxidase, central domain Kelch_5 PF13854.1 CDI75731.1 - 4.9e-17 61.4 2.1 0.0016 18.3 0.0 5.7 5 0 0 5 5 5 4 Kelch motif Kelch_4 PF13418.1 CDI75731.1 - 6.5e-16 57.8 8.1 6.1e-06 25.8 0.1 5.7 5 0 0 5 5 5 4 Galactose oxidase, central domain HATPase_c_3 PF13589.1 CDI75731.1 - 8.9e-10 38.3 0.0 1.7e-09 37.4 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Kelch_1 PF01344.20 CDI75731.1 - 5.9e-05 22.5 0.1 1.4 8.4 0.0 3.9 4 0 0 4 4 4 2 Kelch motif HATPase_c PF02518.21 CDI75731.1 - 0.00018 21.1 0.0 0.00035 20.2 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Kelch_6 PF13964.1 CDI75731.1 - 0.00052 20.0 3.8 0.2 11.9 0.1 4.5 3 1 2 5 5 5 1 Kelch motif PDCD2_C PF04194.8 CDI75732.1 - 7.3e-37 126.4 0.1 7.3e-37 126.4 0.0 1.6 2 0 0 2 2 2 1 Programmed cell death protein 2, C-terminal putative domain zinc_ribbon_2 PF13240.1 CDI75732.1 - 0.048 13.1 4.0 3.5 7.2 0.1 3.5 3 0 0 3 3 3 0 zinc-ribbon domain PhnA_Zn_Ribbon PF08274.7 CDI75732.1 - 0.065 13.0 1.0 0.41 10.4 0.1 2.4 2 0 0 2 2 2 0 PhnA Zinc-Ribbon Lar_restr_allev PF14354.1 CDI75732.1 - 0.087 13.1 0.2 0.087 13.1 0.2 2.9 3 1 0 3 3 3 0 Restriction alleviation protein Lar Zn_Tnp_IS1595 PF12760.2 CDI75732.1 - 0.69 9.7 7.1 1 9.2 0.0 2.7 2 0 0 2 2 2 0 Transposase zinc-ribbon domain vATP-synt_E PF01991.13 CDI75733.1 - 4e-58 195.9 2.3 4.8e-58 195.7 1.6 1.1 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit DUF4239 PF14023.1 CDI75733.1 - 0.042 13.1 5.0 0.12 11.7 3.7 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4239) Rota_NSP3 PF01665.11 CDI75733.1 - 0.056 12.3 4.4 0.068 12.1 3.0 1.1 1 0 0 1 1 1 0 Rotavirus non-structural protein NSP3 CDC37_N PF03234.9 CDI75733.1 - 0.86 9.9 7.9 1 9.6 5.1 1.5 1 1 0 1 1 1 0 Cdc37 N terminal kinase binding HrpE PF06188.7 CDI75733.1 - 9.1 5.9 13.7 47 3.6 9.5 2.0 1 1 0 1 1 1 0 HrpE/YscL/FliH and V-type ATPase subunit E CutA1 PF03091.10 CDI75734.1 - 4.4e-15 55.2 0.1 5.2e-15 54.9 0.0 1.1 1 0 0 1 1 1 1 CutA1 divalent ion tolerance protein Lipase_3 PF01764.20 CDI75735.1 - 2.2e-17 62.9 0.0 3.3e-17 62.3 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.2 CDI75735.1 - 9e-05 22.2 1.4 0.054 13.2 0.0 2.4 2 0 0 2 2 2 2 Alpha/beta hydrolase family Cutinase PF01083.17 CDI75735.1 - 0.029 14.0 0.0 0.078 12.7 0.0 1.6 1 0 0 1 1 1 0 Cutinase MA3 PF02847.12 CDI75737.1 - 1.4e-33 114.9 3.0 2.8e-11 43.0 0.0 3.2 3 0 0 3 3 3 3 MA3 domain B56 PF01603.15 CDI75737.1 - 0.12 10.9 0.0 0.19 10.2 0.0 1.2 1 0 0 1 1 1 0 Protein phosphatase 2A regulatory B subunit (B56 family) PARP PF00644.15 CDI75738.1 - 4.7e-10 39.2 0.0 4.1e-05 23.0 0.0 2.5 2 0 0 2 2 2 2 Poly(ADP-ribose) polymerase catalytic domain Pex16 PF08610.5 CDI75739.1 - 1.1e-21 77.1 0.8 1.1e-21 77.1 0.6 2.9 2 1 0 2 2 2 1 Peroxisomal membrane protein (Pex16) DUF1917 PF08939.5 CDI75739.1 - 0.51 10.0 2.7 0.84 9.3 0.7 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1917) PAT1 PF09770.4 CDI75739.1 - 5.7 5.0 11.7 9.3 4.3 8.1 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Pex14_N PF04695.8 CDI75739.1 - 6.5 6.8 9.4 7.9 6.5 5.4 2.0 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Sec7 PF01369.15 CDI75740.1 - 3e-63 212.9 0.0 4.9e-63 212.2 0.0 1.3 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.2 CDI75740.1 - 1.1e-13 51.0 0.1 3e-13 49.5 0.1 1.8 1 0 0 1 1 1 1 Guanine nucleotide exchange factor in Golgi transport N-terminal Piwi PF02171.12 CDI75742.1 - 1.8e-11 43.5 0.3 2.8e-06 26.5 0.0 3.0 2 1 0 2 2 2 2 Piwi domain PAZ PF02170.17 CDI75742.1 - 2.5e-09 36.5 0.0 9e-09 34.7 0.0 1.9 2 0 0 2 2 2 1 PAZ domain DUF2428 PF10350.4 CDI75743.1 - 1.5e-14 53.6 1.2 1.5e-14 53.6 0.8 3.3 4 0 0 4 4 4 1 Putative death-receptor fusion protein (DUF2428) Biotin_lipoyl PF00364.17 CDI75746.1 - 2.8e-11 42.8 0.3 3.6e-11 42.5 0.2 1.2 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.1 CDI75746.1 - 3.1e-08 33.1 0.2 4e-08 32.7 0.1 1.2 1 0 0 1 1 1 1 Biotin-lipoyl like HlyD PF00529.15 CDI75746.1 - 8e-06 25.3 0.0 8e-06 25.3 0.0 1.1 1 0 0 1 1 1 1 HlyD family secretion protein HlyD_2 PF12700.2 CDI75746.1 - 3.4e-05 23.1 0.0 3.5e-05 23.1 0.0 1.0 1 0 0 1 1 1 1 HlyD family secretion protein PTS_EIIA_1 PF00358.15 CDI75746.1 - 0.017 14.6 0.0 0.023 14.2 0.0 1.1 1 0 0 1 1 1 0 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 HlyD_3 PF13437.1 CDI75746.1 - 0.077 13.3 0.0 0.11 12.9 0.0 1.2 1 0 0 1 1 1 0 HlyD family secretion protein Gag_p12 PF01141.13 CDI75746.1 - 0.094 12.8 5.8 0.13 12.3 4.0 1.2 1 0 0 1 1 1 0 Gag polyprotein, inner coat protein p12 DUF2360 PF10152.4 CDI75746.1 - 0.19 12.0 1.4 0.17 12.1 1.0 1.1 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) Spt20 PF12090.3 CDI75747.1 - 0.1 11.9 0.1 0.1 11.9 0.1 10.0 3 2 1 4 4 4 0 Spt20 family Ras PF00071.17 CDI75748.1 - 6.9e-55 184.8 0.1 6.9e-55 184.8 0.1 2.5 2 1 0 2 2 1 1 Ras family Miro PF08477.8 CDI75748.1 - 2.5e-19 69.9 0.0 2.5e-19 69.9 0.0 3.1 2 1 0 2 2 1 1 Miro-like protein Arf PF00025.16 CDI75748.1 - 4.9e-14 51.9 0.1 4.9e-14 51.9 0.0 2.0 2 1 0 2 2 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 CDI75748.1 - 0.00083 18.5 0.0 0.00083 18.5 0.0 2.2 2 0 0 2 2 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 CDI75748.1 - 0.0019 17.6 0.0 0.0019 17.6 0.0 3.2 2 2 0 2 2 1 1 Elongation factor Tu GTP binding domain TFIIA PF03153.8 CDI75748.1 - 0.0035 17.3 41.4 0.0035 17.3 28.7 2.0 2 0 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit MMR_HSR1 PF01926.18 CDI75748.1 - 0.0049 16.8 0.0 0.0049 16.8 0.0 2.7 3 1 0 3 3 3 1 50S ribosome-binding GTPase RAP1 PF07218.6 CDI75748.1 - 1 7.3 11.0 1.5 6.8 7.6 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) LicD PF04991.8 CDI75748.1 - 1.5 8.9 6.1 2.6 8.0 4.2 1.4 1 0 0 1 1 1 0 LicD family SOBP PF15279.1 CDI75748.1 - 2.3 8.5 28.3 5.6 7.2 19.6 1.6 1 0 0 1 1 1 0 Sine oculis-binding protein Macoilin PF09726.4 CDI75748.1 - 2.4 6.3 40.1 3.5 5.8 27.8 1.1 1 0 0 1 1 1 0 Transmembrane protein Med15 PF09606.5 CDI75749.1 - 0.054 11.6 46.2 0.074 11.2 32.0 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Draxin PF15550.1 CDI75749.1 - 0.074 12.6 11.8 0.091 12.4 8.2 1.1 1 0 0 1 1 1 0 Draxin Pox_Ag35 PF03286.9 CDI75749.1 - 0.12 11.8 5.0 0.14 11.6 3.5 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Mitofilin PF09731.4 CDI75749.1 - 0.19 10.3 17.1 0.21 10.2 11.9 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein NABP PF07990.7 CDI75749.1 - 0.33 10.1 16.7 0.38 9.9 11.6 1.0 1 0 0 1 1 1 0 Nucleic acid binding protein NABP DUF4045 PF13254.1 CDI75749.1 - 0.45 9.7 16.4 0.54 9.4 11.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) MSP1_C PF07462.6 CDI75749.1 - 0.82 7.9 6.2 1.1 7.5 4.3 1.2 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus eIF-3_zeta PF05091.7 CDI75749.1 - 1.2 7.6 15.2 1.5 7.3 10.5 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF4638 PF15472.1 CDI75749.1 - 1.4 8.4 7.2 1.5 8.3 5.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) Ycf1 PF05758.7 CDI75749.1 - 1.6 6.3 10.1 1.6 6.3 7.0 1.0 1 0 0 1 1 1 0 Ycf1 RR_TM4-6 PF06459.7 CDI75749.1 - 1.8 8.3 10.1 2.1 8.1 7.0 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 PCNP PF15473.1 CDI75749.1 - 2.1 8.6 7.0 2.7 8.2 4.9 1.2 1 0 0 1 1 1 0 PEST, proteolytic signal-containing nuclear protein family Hid1 PF12722.2 CDI75749.1 - 2.3 5.7 18.5 2.8 5.5 12.8 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein PAT1 PF09770.4 CDI75749.1 - 3.2 5.8 38.0 3.7 5.6 26.3 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 HGTP_anticodon2 PF12745.2 CDI75749.1 - 3.6 6.6 12.2 4.8 6.2 8.5 1.1 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs PLRV_ORF5 PF01690.12 CDI75749.1 - 4 6.4 15.1 4.4 6.3 10.5 1.0 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein TMEM51 PF15345.1 CDI75749.1 - 4.1 7.0 19.3 4.9 6.7 13.4 1.1 1 0 0 1 1 1 0 Transmembrane protein 51 Lin-8 PF03353.10 CDI75749.1 - 7.7 5.7 17.4 10 5.3 12.1 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Otopetrin PF03189.8 CDI75749.1 - 8.3 5.2 11.5 11 4.8 7.9 1.2 1 0 0 1 1 1 0 Otopetrin PAT1 PF09770.4 CDI75750.1 - 2 6.5 141.9 2.8 6.0 98.4 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Med15 PF09606.5 CDI75751.1 - 0.0029 15.8 56.7 0.0038 15.4 39.3 1.1 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal Hid1 PF12722.2 CDI75751.1 - 0.35 8.4 13.6 0.46 8.1 9.4 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Ndc1_Nup PF09531.5 CDI75751.1 - 0.89 7.9 9.9 0.88 7.9 6.8 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF2079 PF09852.4 CDI75751.1 - 1.2 7.8 8.6 2 7.0 6.0 1.4 1 1 0 1 1 1 0 Predicted membrane protein (DUF2079) Neur_chan_memb PF02932.11 CDI75751.1 - 1.3 8.8 12.0 2 8.2 8.3 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region FAM60A PF15396.1 CDI75751.1 - 2.3 7.9 9.4 3.4 7.3 6.5 1.3 1 0 0 1 1 1 0 Protein Family FAM60A Hom_end_hint PF05203.11 CDI75751.1 - 2.5 7.7 8.6 4 7.1 6.0 1.3 1 0 0 1 1 1 0 Hom_end-associated Hint PAT1 PF09770.4 CDI75751.1 - 2.7 6.1 51.9 3.2 5.8 35.9 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Med15 PF09606.5 CDI75753.1 - 0.00011 20.6 19.7 0.00011 20.6 13.7 5.2 3 2 1 4 4 4 2 ARC105 or Med15 subunit of Mediator complex non-fungal BAF1_ABF1 PF04684.8 CDI75753.1 - 0.00039 19.4 24.7 0.00039 19.4 17.1 10.5 6 3 2 8 8 8 1 BAF1 / ABF1 chromatin reorganising factor Pex14_N PF04695.8 CDI75754.1 - 0.007 16.4 18.1 0.0093 16.0 12.6 1.2 1 0 0 1 1 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF4175 PF13779.1 CDI75754.1 - 0.015 13.0 34.0 0.017 12.8 23.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) SseC PF04888.7 CDI75754.1 - 0.028 13.7 25.6 0.038 13.3 17.7 1.2 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family CIAPIN1 PF05093.8 CDI75754.1 - 0.028 14.4 9.3 0.035 14.1 6.4 1.3 1 0 0 1 1 1 0 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis CD20 PF04103.10 CDI75754.1 - 0.029 14.3 1.9 0.037 13.9 1.3 1.2 1 0 0 1 1 1 0 CD20-like family FAM176 PF14851.1 CDI75754.1 - 0.11 12.2 4.2 0.1 12.2 2.9 1.1 1 0 0 1 1 1 0 FAM176 family NPR3 PF03666.8 CDI75754.1 - 0.12 10.8 8.0 0.12 10.9 5.6 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Trypan_glycop_C PF10659.4 CDI75754.1 - 0.12 12.6 9.6 0.15 12.3 6.6 1.3 1 0 0 1 1 1 0 Trypanosome variant surface glycoprotein C-terminal domain DUF808 PF05661.7 CDI75754.1 - 0.17 10.6 1.4 0.16 10.7 1.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF808) SR-25 PF10500.4 CDI75754.1 - 0.21 11.0 13.3 0.25 10.8 9.2 1.0 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Gly-zipper_OmpA PF13436.1 CDI75754.1 - 0.22 11.1 23.5 0.28 10.8 16.3 1.2 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain Pex16 PF08610.5 CDI75754.1 - 0.24 10.3 9.8 0.25 10.2 6.8 1.0 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) CKAP2_C PF15297.1 CDI75754.1 - 0.27 10.0 10.7 0.29 9.8 7.4 1.0 1 0 0 1 1 1 0 Cytoskeleton-associated protein 2 C-terminus Glyco_transf_15 PF01793.11 CDI75754.1 - 0.35 9.7 11.1 0.37 9.6 7.7 1.0 1 0 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase Dala_Dala_lig_N PF01820.16 CDI75754.1 - 0.35 11.1 4.2 0.4 11.0 2.9 1.2 1 0 0 1 1 1 0 D-ala D-ala ligase N-terminus Med15 PF09606.5 CDI75754.1 - 0.41 8.7 46.6 0.42 8.7 32.3 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal WBS_methylT PF12589.3 CDI75754.1 - 0.47 10.9 15.2 0.61 10.6 10.5 1.1 1 0 0 1 1 1 0 Methyltransferase involved in Williams-Beuren syndrome Band_3_cyto PF07565.8 CDI75754.1 - 0.52 9.7 12.8 0.58 9.6 8.9 1.0 1 0 0 1 1 1 0 Band 3 cytoplasmic domain FAM60A PF15396.1 CDI75754.1 - 0.55 9.9 8.7 0.61 9.8 6.0 1.1 1 0 0 1 1 1 0 Protein Family FAM60A ABC2_membrane_2 PF12679.2 CDI75754.1 - 0.57 9.0 3.8 0.63 8.8 2.6 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein TMEM51 PF15345.1 CDI75754.1 - 0.59 9.7 12.1 0.57 9.8 8.4 1.2 1 0 0 1 1 1 0 Transmembrane protein 51 CDC45 PF02724.9 CDI75754.1 - 0.62 8.0 8.9 0.64 7.9 6.2 1.0 1 0 0 1 1 1 0 CDC45-like protein CTNNB1_binding PF08347.6 CDI75754.1 - 0.69 10.1 9.3 0.8 9.9 6.4 1.0 1 0 0 1 1 1 0 N-terminal CTNNB1 binding UPF0560 PF10577.4 CDI75754.1 - 0.71 8.0 23.0 0.79 7.8 15.9 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Peroxin-13_N PF04088.8 CDI75754.1 - 0.77 9.6 5.5 0.96 9.3 3.8 1.2 1 0 0 1 1 1 0 Peroxin 13, N-terminal region OATP PF03137.15 CDI75754.1 - 0.93 7.4 10.2 1 7.3 7.1 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Serinc PF03348.10 CDI75754.1 - 1 7.9 10.7 0.98 8.0 7.4 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) DUF4557 PF15101.1 CDI75754.1 - 1.1 9.1 26.9 1.2 8.8 18.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) PP_M1 PF03012.9 CDI75754.1 - 1.1 8.6 10.1 1.1 8.5 7.0 1.0 1 0 0 1 1 1 0 Phosphoprotein FLO_LFY PF01698.11 CDI75754.1 - 1.1 8.0 11.6 1.2 7.8 8.0 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein Afi1 PF07792.7 CDI75754.1 - 1.1 9.2 10.6 1.4 8.9 7.4 1.2 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Folate_carrier PF01770.13 CDI75754.1 - 1.2 7.6 7.2 1.2 7.5 5.0 1.1 1 0 0 1 1 1 0 Reduced folate carrier DDHD PF02862.12 CDI75754.1 - 1.2 8.8 11.1 1.4 8.6 7.7 1.2 1 0 0 1 1 1 0 DDHD domain PAT1 PF09770.4 CDI75754.1 - 1.2 7.2 33.7 1.3 7.2 23.4 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 FAM222A PF15258.1 CDI75754.1 - 1.2 8.2 23.9 1.5 7.9 16.5 1.0 1 0 0 1 1 1 0 Protein family of FAM222A Cellulose_synt PF03552.9 CDI75754.1 - 1.3 7.2 5.1 1.1 7.4 3.5 1.0 1 0 0 1 1 1 0 Cellulose synthase PsbW PF07123.7 CDI75754.1 - 1.3 9.0 12.8 1.8 8.5 8.9 1.3 1 0 0 1 1 1 0 Photosystem II reaction centre W protein (PsbW) Raftlin PF15250.1 CDI75754.1 - 1.3 7.4 10.9 1.4 7.3 7.5 1.0 1 0 0 1 1 1 0 Raftlin Mem_trans PF03547.13 CDI75754.1 - 1.3 7.2 4.0 1.5 7.0 2.8 1.1 1 0 0 1 1 1 0 Membrane transport protein PH_4 PF15404.1 CDI75754.1 - 1.3 8.4 9.5 1.4 8.3 6.6 1.1 1 0 0 1 1 1 0 Pleckstrin homology domain Hid1 PF12722.2 CDI75754.1 - 1.3 6.5 12.2 1.4 6.5 8.4 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Gti1_Pac2 PF09729.4 CDI75754.1 - 1.4 8.7 9.7 1.6 8.5 6.8 1.1 1 0 0 1 1 1 0 Gti1/Pac2 family VIT1 PF01988.14 CDI75754.1 - 1.5 8.2 7.2 1.9 7.9 5.0 1.2 1 0 0 1 1 1 0 VIT family DDRGK PF09756.4 CDI75754.1 - 1.6 8.1 18.2 1.8 7.9 12.6 1.0 1 0 0 1 1 1 0 DDRGK domain DUF4199 PF13858.1 CDI75754.1 - 2.1 8.2 8.3 2.5 8.0 5.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) Spore_coat_CotO PF14153.1 CDI75754.1 - 2.1 7.7 18.6 2.3 7.6 12.9 1.1 1 0 0 1 1 1 0 Spore coat protein CotO Neur_chan_memb PF02932.11 CDI75754.1 - 2.1 8.1 8.3 2.2 8.1 5.8 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Ycf1 PF05758.7 CDI75754.1 - 2.4 5.7 11.2 2.5 5.7 7.8 1.0 1 0 0 1 1 1 0 Ycf1 eIF-3_zeta PF05091.7 CDI75754.1 - 2.4 6.6 18.1 2.5 6.6 12.5 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF4045 PF13254.1 CDI75754.1 - 2.5 7.2 13.6 3 7.0 9.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) SAGA-Tad1 PF12767.2 CDI75754.1 - 2.5 7.6 16.7 2.7 7.5 11.6 1.1 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit Kei1 PF08552.6 CDI75754.1 - 2.5 7.7 12.2 2.9 7.5 8.5 1.2 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 Suf PF05843.9 CDI75754.1 - 2.6 7.7 19.7 2.9 7.5 13.6 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) MRP-S31 PF15433.1 CDI75754.1 - 2.6 7.3 15.4 3 7.2 10.7 1.1 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 PIH1 PF08190.7 CDI75754.1 - 2.6 7.3 19.4 2.9 7.2 13.4 1.0 1 0 0 1 1 1 0 pre-RNA processing PIH1/Nop17 AUX_IAA PF02309.11 CDI75754.1 - 2.8 7.6 12.6 3 7.5 8.7 1.1 1 0 0 1 1 1 0 AUX/IAA family DUF913 PF06025.7 CDI75754.1 - 2.9 6.5 6.4 3 6.5 4.4 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) EIIBC-GUT_N PF03612.9 CDI75754.1 - 3.1 7.3 11.2 3.5 7.1 7.8 1.2 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Plasmodium_Vir PF05795.6 CDI75754.1 - 3.1 6.8 5.5 3 6.9 3.8 1.0 1 0 0 1 1 1 0 Plasmodium vivax Vir protein DUF912 PF06024.7 CDI75754.1 - 3.2 7.8 9.2 4.7 7.3 6.4 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Paramyxo_ncap PF00973.14 CDI75754.1 - 3.4 6.2 9.5 3.6 6.1 6.6 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein NMDAR2_C PF10565.4 CDI75754.1 - 3.7 6.0 13.0 3.7 6.1 9.0 1.1 1 0 0 1 1 1 0 N-methyl D-aspartate receptor 2B3 C-terminus TFIIA PF03153.8 CDI75754.1 - 3.8 7.3 27.5 4.5 7.0 19.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF2215 PF10225.4 CDI75754.1 - 4 6.8 6.1 4.4 6.6 4.2 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) Dynamin_N PF00350.18 CDI75754.1 - 4.1 7.1 7.5 4.7 7.0 5.2 1.1 1 0 0 1 1 1 0 Dynamin family DUF966 PF06136.8 CDI75754.1 - 4.2 6.7 15.5 4.8 6.4 10.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF966) DUF1675 PF07897.6 CDI75754.1 - 4.2 7.1 14.4 4.4 7.0 10.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) Peptidase_S49_N PF08496.5 CDI75754.1 - 4.3 7.1 12.2 5.2 6.8 8.5 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal SLD3 PF08639.5 CDI75754.1 - 4.3 5.8 15.7 4.3 5.8 10.9 1.0 1 0 0 1 1 1 0 DNA replication regulator SLD3 HGTP_anticodon2 PF12745.2 CDI75754.1 - 4.3 6.3 11.5 4.9 6.2 8.0 1.1 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs Tim54 PF11711.3 CDI75754.1 - 4.4 5.8 9.2 4.5 5.7 6.3 1.0 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 CPSF100_C PF13299.1 CDI75754.1 - 4.6 7.3 11.4 5.1 7.2 7.9 1.1 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal DUF2217 PF10265.4 CDI75754.1 - 5 5.7 8.9 5.5 5.6 6.2 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) Bul1_N PF04425.7 CDI75754.1 - 5.1 5.5 9.8 5.2 5.5 6.8 1.0 1 0 0 1 1 1 0 Bul1 N terminus Peptidase_S64 PF08192.6 CDI75754.1 - 5.2 5.2 12.0 6.1 5.0 8.3 1.0 1 0 0 1 1 1 0 Peptidase family S64 SID-1_RNA_chan PF13965.1 CDI75754.1 - 5.6 5.0 5.5 5.6 5.0 3.8 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 SeqA PF03925.8 CDI75754.1 - 5.7 6.5 11.3 6.1 6.4 7.9 1.1 1 0 0 1 1 1 0 SeqA protein Ctr PF04145.10 CDI75754.1 - 6.4 6.8 11.7 7.7 6.5 8.1 1.1 1 0 0 1 1 1 0 Ctr copper transporter family G-alpha PF00503.15 CDI75754.1 - 6.8 5.2 12.3 7.1 5.2 8.5 1.0 1 0 0 1 1 1 0 G-protein alpha subunit eIF3_subunit PF08597.5 CDI75754.1 - 6.8 6.1 14.3 6.9 6.1 9.9 1.2 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit ATAD4 PF15321.1 CDI75754.1 - 7 7.7 13.5 9.6 7.2 9.4 1.3 1 0 0 1 1 1 0 ATPase family AAA domain containing 4 Spc7_N PF15402.1 CDI75754.1 - 7.1 4.4 17.0 8 4.3 11.8 1.0 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 FemAB PF02388.11 CDI75754.1 - 7.4 5.1 15.6 8 5.0 10.8 1.0 1 0 0 1 1 1 0 FemAB family RR_TM4-6 PF06459.7 CDI75754.1 - 7.4 6.3 14.6 8.1 6.2 10.1 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SAPS PF04499.10 CDI75754.1 - 7.9 4.9 10.8 8.1 4.9 7.5 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein vMSA PF00695.14 CDI75754.1 - 8.3 5.4 7.4 9.4 5.3 5.1 1.0 1 0 0 1 1 1 0 Major surface antigen from hepadnavirus DNA_pol_viral_N PF00242.12 CDI75754.1 - 8.5 5.2 14.0 9.2 5.1 9.7 1.1 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain DUF4647 PF15504.1 CDI75754.1 - 8.8 5.0 17.9 9.9 4.8 12.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4647) NARP1 PF12569.3 CDI75754.1 - 9 4.9 14.7 9.2 4.8 10.2 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 EPL1 PF10513.4 CDI75754.1 - 9.9 6.3 14.2 12 6.1 9.8 1.1 1 0 0 1 1 1 0 Enhancer of polycomb-like DUF1266 PF06889.6 CDI75755.1 - 0.04 13.7 23.5 0.085 12.6 4.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1266) CD20 PF04103.10 CDI75755.1 - 0.043 13.7 0.9 0.043 13.7 0.6 2.6 3 0 0 3 3 2 0 CD20-like family Daxx PF03344.10 CDI75755.1 - 0.14 10.6 25.5 0.17 10.3 17.7 1.0 1 0 0 1 1 1 0 Daxx Family Gti1_Pac2 PF09729.4 CDI75755.1 - 0.17 11.7 14.0 0.047 13.5 1.5 2.1 2 0 0 2 2 2 0 Gti1/Pac2 family FimP PF09766.4 CDI75755.1 - 0.48 9.4 44.3 0.2 10.7 15.7 2.1 2 0 0 2 2 2 0 Fms-interacting protein DUF4199 PF13858.1 CDI75755.1 - 0.76 9.6 19.7 0.58 10.0 4.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4199) Afi1 PF07792.7 CDI75755.1 - 0.78 9.7 25.5 1.3 9.0 6.9 2.1 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking MRP-S31 PF15433.1 CDI75755.1 - 0.89 8.9 35.0 1.3 8.3 24.3 1.2 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 Pex16 PF08610.5 CDI75755.1 - 2.1 7.2 27.8 1.8 7.5 7.1 2.1 2 0 0 2 2 2 0 Peroxisomal membrane protein (Pex16) XAP5 PF04921.9 CDI75755.1 - 2.5 7.6 19.9 0.69 9.4 5.0 2.1 2 0 0 2 2 2 0 XAP5, circadian clock regulator CDC45 PF02724.9 CDI75755.1 - 2.6 5.9 18.0 0.13 10.2 3.3 2.0 2 0 0 2 2 2 0 CDC45-like protein Ycf1 PF05758.7 CDI75755.1 - 2.9 5.4 22.5 0.18 9.4 4.8 2.0 2 0 0 2 2 2 0 Ycf1 EIIBC-GUT_N PF03612.9 CDI75755.1 - 3.3 7.2 24.2 1.6 8.3 6.1 2.2 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus Parvo_coat PF00740.13 CDI75755.1 - 6.6 5.5 35.4 7.4 5.3 24.6 1.0 1 0 0 1 1 1 0 Parvovirus coat protein VP2 PRP1_N PF06424.7 CDI75755.1 - 6.8 7.0 21.6 2.3 8.5 4.5 2.3 2 0 0 2 2 2 0 PRP1 splicing factor, N-terminal DUF572 PF04502.8 CDI75755.1 - 7.2 5.7 28.1 10 5.2 19.5 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF3464 PF11947.3 CDI75755.1 - 7.8 5.9 25.1 3.7 7.0 6.9 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3464) Na_trans_assoc PF06512.8 CDI75755.1 - 8.1 6.3 20.3 4.8 7.0 3.2 2.1 2 0 0 2 2 2 0 Sodium ion transport-associated SR-25 PF10500.4 CDI75755.1 - 9.7 5.5 26.5 4.3 6.7 6.8 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein DUF615 PF04751.9 CDI75756.1 - 0.099 12.2 1.3 6.2 6.4 0.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF615) SpoIIIAH PF12685.2 CDI75757.1 - 0.49 9.8 1.2 1.3 8.5 0.0 2.0 2 0 0 2 2 2 0 SpoIIIAH-like protein Ribosomal_60s PF00428.14 CDI75758.1 - 9.6 6.6 21.5 2.3 8.6 4.3 3.2 3 0 0 3 3 3 0 60s Acidic ribosomal protein DUF501 PF04417.7 CDI75759.1 - 0.0079 16.0 0.3 0.23 11.3 0.0 2.6 1 1 1 2 2 2 1 Protein of unknown function (DUF501) DUF4475 PF14753.1 CDI75761.1 - 2e-05 24.1 0.4 2e-05 24.1 0.3 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4475) Rtf2 PF04641.7 CDI75761.1 - 0.00021 20.5 14.1 0.00024 20.3 9.7 1.1 1 0 0 1 1 1 1 Rtf2 RING-finger DUF605 PF04652.11 CDI75761.1 - 0.034 13.5 23.6 0.034 13.5 16.3 1.1 1 0 0 1 1 1 0 Vta1 like Hepar_II_III PF07940.8 CDI75761.1 - 0.1 12.4 0.3 0.16 11.8 0.2 1.5 1 1 0 1 1 1 0 Heparinase II/III-like protein DDHD PF02862.12 CDI75761.1 - 0.17 11.6 13.8 0.18 11.5 9.5 1.2 1 0 0 1 1 1 0 DDHD domain Myticin-prepro PF10690.4 CDI75761.1 - 0.2 11.7 2.4 0.47 10.5 1.7 1.8 1 1 0 1 1 1 0 Myticin pre-proprotein from the mussel FAM60A PF15396.1 CDI75761.1 - 0.38 10.4 16.6 0.5 10.0 11.5 1.2 1 0 0 1 1 1 0 Protein Family FAM60A SpaB_C PF14028.1 CDI75761.1 - 0.46 10.0 4.0 0.59 9.6 2.8 1.3 1 0 0 1 1 1 0 SpaB C-terminal domain GAGA_bind PF06217.7 CDI75761.1 - 0.6 10.0 17.9 0.68 9.8 12.4 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family FMN_dh PF01070.13 CDI75761.1 - 1.1 8.0 4.7 1.1 8.0 3.3 1.1 1 0 0 1 1 1 0 FMN-dependent dehydrogenase DUF1501 PF07394.7 CDI75761.1 - 1.2 7.9 16.3 1.2 7.8 11.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) Herpes_DNAp_acc PF04929.7 CDI75761.1 - 1.7 7.4 20.2 2.2 7.1 14.0 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor NPR3 PF03666.8 CDI75761.1 - 2 6.8 20.9 2.3 6.6 14.5 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Med15 PF09606.5 CDI75761.1 - 5.3 5.1 62.0 6.1 4.9 43.0 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF2215 PF10225.4 CDI75761.1 - 6.1 6.2 10.8 8.1 5.8 7.5 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) CDC45 PF02724.9 CDI75761.1 - 7.3 4.4 21.5 8.9 4.2 14.9 1.0 1 0 0 1 1 1 0 CDC45-like protein Ycf1 PF05758.7 CDI75761.1 - 7.9 4.0 20.0 9 3.8 13.8 1.0 1 0 0 1 1 1 0 Ycf1 Mucin PF01456.12 CDI75762.1 - 0.0036 17.0 11.0 0.0036 17.0 7.6 2.5 2 0 0 2 2 2 1 Mucin-like glycoprotein DUF2052 PF09747.4 CDI75762.1 - 1.1 9.1 46.5 0.15 11.9 11.7 2.3 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) Med15 PF09606.5 CDI75763.1 - 0.00037 18.8 39.8 0.00048 18.4 27.6 1.3 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal ArfGap PF01412.13 CDI75763.1 - 0.049 13.4 1.8 0.19 11.5 0.1 2.2 2 0 0 2 2 2 0 Putative GTPase activating protein for Arf PAT1 PF09770.4 CDI75763.1 - 0.064 11.4 36.0 0.09 11.0 25.0 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TAP42 PF04177.7 CDI75763.1 - 0.16 10.8 18.3 0.063 12.2 3.0 2.1 2 0 0 2 2 2 0 TAP42-like family HABP4_PAI-RBP1 PF04774.10 CDI75763.1 - 0.97 9.9 11.4 0.28 11.7 1.1 2.3 2 0 0 2 2 2 0 Hyaluronan / mRNA binding family Pex14_N PF04695.8 CDI75763.1 - 1.9 8.4 34.8 0.26 11.3 9.7 2.7 1 1 2 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Activator_LAG-3 PF11498.3 CDI75763.1 - 2.9 6.5 52.2 0.28 9.8 10.5 2.2 2 0 0 2 2 2 0 Transcriptional activator LAG-3 DFF40 PF09230.5 CDI75763.1 - 6.8 5.9 8.1 0.37 10.1 0.7 1.9 2 0 0 2 2 2 0 DNA fragmentation factor 40 kDa MIP-T3 PF10243.4 CDI75765.1 - 1.3 7.4 65.1 1.6 7.1 45.1 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Trypan_PARP PF05887.6 CDI75765.1 - 3.4 7.4 28.2 1.5 8.6 7.6 2.1 1 1 1 2 2 2 0 Procyclic acidic repetitive protein (PARP) DUF4603 PF15376.1 CDI75766.1 - 0.0015 15.8 3.4 0.0016 15.7 2.4 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4603) Presenilin PF01080.12 CDI75766.1 - 0.029 13.1 4.1 0.03 13.1 2.8 1.0 1 0 0 1 1 1 0 Presenilin Gastrin PF00918.12 CDI75766.1 - 0.049 14.4 16.4 0.069 13.9 11.4 1.1 1 0 0 1 1 1 0 Gastrin/cholecystokinin family FAP PF07174.6 CDI75766.1 - 0.061 12.6 3.8 0.074 12.3 2.6 1.1 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) DUF1510 PF07423.6 CDI75766.1 - 0.078 12.3 5.7 0.093 12.0 3.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Macoilin PF09726.4 CDI75766.1 - 0.09 11.0 12.8 0.13 10.4 8.9 1.3 1 0 0 1 1 1 0 Transmembrane protein DUF3450 PF11932.3 CDI75766.1 - 0.091 12.0 20.7 0.11 11.6 14.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF2140 PF09911.4 CDI75766.1 - 0.094 11.8 0.2 0.12 11.5 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2140) CAF-1_p150 PF11600.3 CDI75766.1 - 0.1 11.9 11.8 0.13 11.6 8.2 1.0 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF1180 PF06679.7 CDI75766.1 - 0.16 11.8 2.3 0.19 11.5 1.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Herpes_DNAp_acc PF04929.7 CDI75766.1 - 0.19 10.6 8.9 0.21 10.5 6.2 1.0 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Spc7_N PF15402.1 CDI75766.1 - 0.21 9.5 20.3 0.25 9.2 14.1 1.0 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 Med15 PF09606.5 CDI75766.1 - 0.3 9.2 39.4 0.31 9.1 27.3 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal FAM60A PF15396.1 CDI75766.1 - 0.4 10.4 8.2 0.43 10.2 5.7 1.1 1 0 0 1 1 1 0 Protein Family FAM60A RR_TM4-6 PF06459.7 CDI75766.1 - 0.41 10.4 10.9 0.46 10.3 7.6 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF3984 PF13136.1 CDI75766.1 - 0.41 9.8 18.7 0.49 9.5 12.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3984) DUF4557 PF15101.1 CDI75766.1 - 0.5 10.1 15.3 0.61 9.8 10.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) Serinc PF03348.10 CDI75766.1 - 0.52 8.9 6.4 0.59 8.7 4.5 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) Pex16 PF08610.5 CDI75766.1 - 0.66 8.9 7.1 0.84 8.5 4.9 1.2 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) Gag_spuma PF03276.9 CDI75766.1 - 0.68 8.2 19.2 0.76 8.0 13.3 1.1 1 0 0 1 1 1 0 Spumavirus gag protein eIF-3_zeta PF05091.7 CDI75766.1 - 0.88 8.1 14.0 0.99 7.9 9.7 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Tim54 PF11711.3 CDI75766.1 - 0.89 8.0 11.7 1 7.8 8.1 1.0 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Sec62 PF03839.11 CDI75766.1 - 0.97 8.7 4.5 1 8.6 3.1 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 TCP PF03634.8 CDI75766.1 - 0.98 9.7 18.6 1.3 9.3 12.9 1.2 1 0 0 1 1 1 0 TCP family transcription factor Peptidase_S49_N PF08496.5 CDI75766.1 - 0.99 9.1 6.5 1.3 8.7 4.5 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF4175 PF13779.1 CDI75766.1 - 1 7.0 30.2 1.1 6.8 20.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Exonuc_VII_L PF02601.10 CDI75766.1 - 1.2 8.2 14.6 1.5 7.9 10.1 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF4045 PF13254.1 CDI75766.1 - 1.3 8.2 10.5 1.5 8.0 7.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Band_3_cyto PF07565.8 CDI75766.1 - 1.5 8.2 10.9 1.8 8.0 7.5 1.3 1 0 0 1 1 1 0 Band 3 cytoplasmic domain PAT1 PF09770.4 CDI75766.1 - 2 6.5 42.5 2.1 6.4 29.4 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Nha1_C PF08619.5 CDI75766.1 - 2.5 7.2 14.7 2.8 7.1 10.2 1.0 1 0 0 1 1 1 0 Alkali metal cation/H+ antiporter Nha1 C terminus AUX_IAA PF02309.11 CDI75766.1 - 3 7.5 8.5 3.4 7.3 5.9 1.1 1 0 0 1 1 1 0 AUX/IAA family Neur_chan_memb PF02932.11 CDI75766.1 - 3.1 7.6 12.1 3.5 7.4 8.4 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Hid1 PF12722.2 CDI75766.1 - 3.3 5.2 12.0 3.5 5.1 8.3 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein CDK5_activator PF03261.10 CDI75766.1 - 3.3 6.9 11.9 3.8 6.7 8.3 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein Paramyxo_ncap PF00973.14 CDI75766.1 - 3.4 6.2 8.0 3.6 6.1 5.5 1.0 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein DUF605 PF04652.11 CDI75766.1 - 3.6 6.8 24.1 4.2 6.6 16.7 1.1 1 0 0 1 1 1 0 Vta1 like DUF3260 PF11658.3 CDI75766.1 - 3.7 5.5 12.9 4.4 5.3 8.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3260) DDRGK PF09756.4 CDI75766.1 - 3.8 6.8 15.9 4.8 6.5 11.0 1.1 1 0 0 1 1 1 0 DDRGK domain RCR PF12273.3 CDI75766.1 - 4.1 7.9 21.0 5.3 7.5 14.5 1.3 1 0 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red MMR1 PF08505.5 CDI75766.1 - 4.7 7.1 17.7 5.9 6.8 12.3 1.1 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein Asp-B-Hydro_N PF05279.6 CDI75766.1 - 5 6.9 7.4 5.3 6.8 5.1 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region DUF1387 PF07139.6 CDI75766.1 - 5.2 6.5 12.7 6.2 6.3 8.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) FliP PF00813.15 CDI75766.1 - 5.2 6.7 6.1 5.7 6.5 4.2 1.1 1 0 0 1 1 1 0 FliP family TFIIA PF03153.8 CDI75766.1 - 5.5 6.7 28.6 6.2 6.6 19.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Pox_Ag35 PF03286.9 CDI75766.1 - 5.6 6.4 8.2 7.1 6.1 5.7 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Med5 PF08689.5 CDI75766.1 - 5.8 4.4 11.5 6 4.4 7.9 1.0 1 0 0 1 1 1 0 Mediator complex subunit Med5 Endostatin PF06482.6 CDI75766.1 - 8.6 5.6 14.8 10 5.4 10.3 1.1 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin Nop14 PF04147.7 CDI75767.1 - 0.12 10.3 39.6 0.22 9.3 27.4 1.5 1 0 0 1 1 1 0 Nop14-like family Daxx PF03344.10 CDI75767.1 - 0.12 10.8 52.7 0.16 10.4 36.6 1.0 1 0 0 1 1 1 0 Daxx Family YajC PF02699.10 CDI75768.1 - 0.3 10.7 1.2 0.52 10.0 0.9 1.3 1 0 0 1 1 1 0 Preprotein translocase subunit Utp14 PF04615.8 CDI75768.1 - 3.8 5.5 11.9 3.8 5.5 8.3 1.2 1 0 0 1 1 1 0 Utp14 protein GAGA_bind PF06217.7 CDI75769.1 - 0.00092 19.2 13.3 0.00092 19.2 9.2 3.6 3 1 0 3 3 3 1 GAGA binding protein-like family Herpes_UL87 PF03043.9 CDI75769.1 - 0.081 11.3 19.2 0.84 7.9 12.2 2.3 1 1 1 2 2 2 0 Herpesvirus UL87 family SAGA-Tad1 PF12767.2 CDI75769.1 - 0.59 9.7 42.5 0.25 10.9 6.3 3.1 3 0 0 3 3 3 0 Transcriptional regulator of RNA polII, SAGA, subunit PAT1 PF09770.4 CDI75769.1 - 1.2 7.2 98.7 0.069 11.3 31.6 3.2 3 0 0 3 3 3 0 Topoisomerase II-associated protein PAT1 CAF-1_p150 PF11600.3 CDI75771.1 - 0.11 11.7 64.0 0.19 11.0 44.4 1.3 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal zf-C3HC4_4 PF15227.1 CDI75773.1 - 1.4e-06 28.0 10.0 6.9e-06 25.8 6.9 2.3 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.1 CDI75773.1 - 1.2e-05 25.0 11.2 2.4e-05 24.0 7.8 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 CDI75773.1 - 5.7e-05 23.0 9.6 0.00011 22.1 6.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Macoilin PF09726.4 CDI75773.1 - 7.5e-05 21.2 36.2 0.0001 20.7 25.1 1.1 1 0 0 1 1 1 1 Transmembrane protein zf-C3HC4 PF00097.20 CDI75773.1 - 0.0019 17.7 10.3 0.005 16.4 7.1 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 CDI75773.1 - 0.014 15.1 7.3 0.075 12.7 4.8 2.5 1 1 1 2 2 2 0 RING-type zinc-finger zf-C3HC4_3 PF13920.1 CDI75773.1 - 0.031 13.9 7.9 0.064 12.9 5.5 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 CDI75773.1 - 0.15 11.9 6.3 0.47 10.3 4.4 1.9 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.1 CDI75773.1 - 0.35 10.6 14.9 3.4 7.4 10.6 2.4 1 1 1 2 2 2 0 zinc-RING finger domain zf-rbx1 PF12678.2 CDI75773.1 - 0.95 9.6 12.9 2.8 8.1 8.9 1.8 1 1 0 1 1 1 0 RING-H2 zinc finger DUF2229 PF09989.4 CDI75773.1 - 3.4 7.0 8.0 7.9 5.8 5.5 1.5 1 0 0 1 1 1 0 CoA enzyme activase uncharacterised domain (DUF2229) AMP-binding_C_2 PF14535.1 CDI75773.1 - 3.6 7.7 9.4 53 3.9 6.5 2.3 1 1 0 1 1 1 0 AMP-binding enzyme C-terminal domain Fasciclin PF02469.17 CDI75773.1 - 5.5 6.9 10.0 12 5.9 6.9 1.5 1 0 0 1 1 1 0 Fasciclin domain WW PF00397.21 CDI75774.1 - 5.8e-09 35.6 2.2 9.6e-09 34.9 1.6 1.4 1 0 0 1 1 1 1 WW domain DUF1510 PF07423.6 CDI75774.1 - 5.3e-05 22.6 0.8 0.00018 20.9 0.6 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) Yip1 PF04893.12 CDI75774.1 - 0.00012 21.6 14.3 0.0032 16.9 9.5 3.2 2 1 1 3 3 3 1 Yip1 domain YIF1 PF03878.10 CDI75774.1 - 0.011 14.9 0.3 1.3 8.1 0.0 2.3 2 0 0 2 2 2 0 YIF1 Neur_chan_memb PF02932.11 CDI75774.1 - 5.7 6.7 10.5 0.076 12.8 1.1 2.3 2 1 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Bud13 PF09736.4 CDI75776.1 - 0.01 16.0 14.9 0.01 16.0 10.3 1.9 2 1 0 2 2 2 0 Pre-mRNA-splicing factor of RES complex PTPlike_phytase PF14566.1 CDI75776.1 - 0.41 10.6 5.4 0.85 9.6 3.7 1.5 1 0 0 1 1 1 0 Inositol hexakisphosphate DUF1777 PF08648.7 CDI75779.1 - 0.83 9.3 132.7 3.8 7.2 36.3 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF1777) MIP-T3 PF10243.4 CDI75779.1 - 3.6 5.9 74.4 4.9 5.5 51.6 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DNA_topoisoIV PF00521.15 CDI75781.1 - 1.5e-21 76.7 1.2 2.2e-21 76.1 0.8 1.3 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A Queuosine_synth PF02547.10 CDI75781.1 - 0.026 13.2 0.1 0.041 12.6 0.1 1.2 1 0 0 1 1 1 0 Queuosine biosynthesis protein Ribosomal_60s PF00428.14 CDI75782.1 - 8.3 6.8 30.3 4.9 7.6 7.6 2.7 2 0 0 2 2 2 0 60s Acidic ribosomal protein SAPS PF04499.10 CDI75783.1 - 0.016 13.8 16.8 0.015 13.9 11.6 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein GAGA_bind PF06217.7 CDI75783.1 - 0.042 13.8 19.6 0.045 13.7 13.6 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family Tim54 PF11711.3 CDI75783.1 - 0.09 11.3 9.0 0.099 11.2 6.2 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 AUX_IAA PF02309.11 CDI75783.1 - 0.2 11.4 16.1 0.22 11.2 11.2 1.2 1 0 0 1 1 1 0 AUX/IAA family PIH1 PF08190.7 CDI75783.1 - 0.3 10.4 22.7 0.36 10.2 15.7 1.3 1 0 0 1 1 1 0 pre-RNA processing PIH1/Nop17 RCR PF12273.3 CDI75783.1 - 0.44 11.1 29.4 0.55 10.7 20.4 1.3 1 0 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red Parvo_coat PF00740.13 CDI75783.1 - 1.2 8.0 29.4 1.3 7.8 20.4 1.1 1 0 0 1 1 1 0 Parvovirus coat protein VP2 Herpes_env PF01673.13 CDI75783.1 - 1.4 7.3 21.2 1.6 7.1 14.7 1.0 1 0 0 1 1 1 0 Herpesvirus putative major envelope glycoprotein NPR3 PF03666.8 CDI75783.1 - 1.7 7.1 26.5 2.1 6.7 18.4 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 AvrE PF11725.3 CDI75783.1 - 2.3 5.1 24.7 2.2 5.1 17.1 1.0 1 0 0 1 1 1 0 Pathogenicity factor CDC45 PF02724.9 CDI75783.1 - 2.8 5.8 26.0 3.2 5.6 18.0 1.0 1 0 0 1 1 1 0 CDC45-like protein HlyD_2 PF12700.2 CDI75783.1 - 3.3 6.7 14.9 3.3 6.7 10.3 1.1 1 0 0 1 1 1 0 HlyD family secretion protein DHHW PF14286.1 CDI75783.1 - 3.9 6.6 17.9 4.1 6.6 12.4 1.1 1 0 0 1 1 1 0 DHHW protein HCO3_cotransp PF00955.16 CDI75783.1 - 4.7 5.7 12.5 6.1 5.3 8.7 1.1 1 0 0 1 1 1 0 HCO3- transporter family SPX PF03105.14 CDI75783.1 - 6.5 6.4 23.0 6.9 6.3 15.9 1.1 1 0 0 1 1 1 0 SPX domain CKAP2_C PF15297.1 CDI75783.1 - 7.2 5.3 25.9 8.5 5.0 18.0 1.1 1 0 0 1 1 1 0 Cytoskeleton-associated protein 2 C-terminus FimP PF09766.4 CDI75784.1 - 0.0003 19.9 8.8 0.00032 19.8 6.1 1.0 1 0 0 1 1 1 1 Fms-interacting protein Conotoxin PF02950.12 CDI75784.1 - 0.00035 21.3 2.3 0.00035 21.3 1.6 1.4 2 0 0 2 2 1 1 Conotoxin Activator_LAG-3 PF11498.3 CDI75784.1 - 0.0032 16.2 26.6 0.0032 16.2 18.4 1.1 1 0 0 1 1 1 1 Transcriptional activator LAG-3 RskA PF10099.4 CDI75784.1 - 0.0033 17.1 5.6 0.0041 16.8 3.9 1.2 1 0 0 1 1 1 1 Anti-sigma-K factor rskA DUF897 PF05982.7 CDI75784.1 - 0.0063 15.3 2.7 0.0068 15.2 1.9 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF897) FHIPEP PF00771.15 CDI75784.1 - 0.0064 14.8 4.1 0.0069 14.7 2.8 1.0 1 0 0 1 1 1 1 FHIPEP family DUF3260 PF11658.3 CDI75784.1 - 0.017 13.2 3.4 0.017 13.3 2.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3260) Gag_spuma PF03276.9 CDI75784.1 - 0.017 13.4 9.7 0.015 13.6 6.7 1.1 1 0 0 1 1 1 0 Spumavirus gag protein Mem_trans PF03547.13 CDI75784.1 - 0.019 13.2 1.9 0.019 13.3 1.3 1.2 1 0 0 1 1 1 0 Membrane transport protein OSTbeta PF15048.1 CDI75784.1 - 0.021 14.9 0.8 0.023 14.7 0.6 1.3 1 0 0 1 1 1 0 Organic solute transporter subunit beta protein Spt20 PF12090.3 CDI75784.1 - 0.024 13.9 6.3 0.029 13.7 4.3 1.3 1 0 0 1 1 1 0 Spt20 family Med15 PF09606.5 CDI75784.1 - 0.024 12.8 28.3 0.024 12.8 19.6 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Cons_hypoth698 PF03601.9 CDI75784.1 - 0.033 12.8 2.1 0.044 12.4 1.5 1.3 1 1 0 1 1 1 0 Conserved hypothetical protein 698 zf-DHHC PF01529.15 CDI75784.1 - 0.048 13.0 2.5 0.059 12.7 1.7 1.1 1 0 0 1 1 1 0 DHHC palmitoyltransferase Suf PF05843.9 CDI75784.1 - 0.057 13.1 10.2 0.058 13.1 7.1 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Serinc PF03348.10 CDI75784.1 - 0.063 11.9 5.2 0.06 12.0 3.6 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) R_equi_Vir PF05526.6 CDI75784.1 - 0.063 12.9 3.1 0.071 12.7 2.1 1.1 1 0 0 1 1 1 0 Rhodococcus equi virulence-associated protein TRC8_N PF13705.1 CDI75784.1 - 0.067 11.7 0.4 0.085 11.4 0.3 1.1 1 0 0 1 1 1 0 TRC8 N-terminal domain DUF3959 PF13105.1 CDI75784.1 - 0.069 12.4 1.3 0.083 12.2 0.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3959) Virul_fac_BrkB PF03631.10 CDI75784.1 - 0.07 12.4 1.6 0.083 12.2 1.1 1.1 1 0 0 1 1 1 0 Virulence factor BrkB ATAD4 PF15321.1 CDI75784.1 - 0.087 13.8 2.9 0.09 13.7 2.0 1.3 1 0 0 1 1 1 0 ATPase family AAA domain containing 4 Peptidase_S49_N PF08496.5 CDI75784.1 - 0.091 12.5 2.9 0.13 12.0 2.0 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Parvo_coat PF00740.13 CDI75784.1 - 0.13 11.2 8.4 0.13 11.1 5.8 1.0 1 0 0 1 1 1 0 Parvovirus coat protein VP2 PIG-U PF06728.8 CDI75784.1 - 0.13 11.0 0.1 0.14 10.9 0.0 1.1 1 0 0 1 1 1 0 GPI transamidase subunit PIG-U Oleosin PF01277.12 CDI75784.1 - 0.16 11.5 1.7 0.21 11.1 1.2 1.2 1 0 0 1 1 1 0 Oleosin eIF_4EBP PF05456.6 CDI75784.1 - 0.16 11.6 5.4 0.21 11.3 3.7 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) SHR3_chaperone PF08229.6 CDI75784.1 - 0.16 10.8 6.3 0.18 10.7 4.3 1.2 1 0 0 1 1 1 0 ER membrane protein SH3 Bac_luciferase PF00296.15 CDI75784.1 - 0.17 10.9 1.4 0.17 10.9 1.0 1.0 1 0 0 1 1 1 0 Luciferase-like monooxygenase Band_3_cyto PF07565.8 CDI75784.1 - 0.21 11.0 4.7 0.2 11.1 3.2 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Ycf1 PF05758.7 CDI75784.1 - 0.23 9.1 5.3 0.21 9.2 3.6 1.0 1 0 0 1 1 1 0 Ycf1 YfhO PF09586.5 CDI75784.1 - 0.23 9.4 1.3 0.22 9.4 0.9 1.0 1 0 0 1 1 1 0 Bacterial membrane protein YfhO Folate_carrier PF01770.13 CDI75784.1 - 0.23 9.9 1.6 0.22 9.9 1.1 1.2 1 0 0 1 1 1 0 Reduced folate carrier UPF0560 PF10577.4 CDI75784.1 - 0.27 9.4 10.4 0.24 9.6 7.2 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Peptidase_S15 PF02129.13 CDI75784.1 - 0.3 10.4 5.0 0.39 10.1 3.5 1.2 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Glt_symporter PF03616.9 CDI75784.1 - 0.34 9.3 1.5 0.38 9.1 1.0 1.1 1 0 0 1 1 1 0 Sodium/glutamate symporter Herpes_DNAp_acc PF04929.7 CDI75784.1 - 0.38 9.6 7.0 0.39 9.6 4.8 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor TMEM154 PF15102.1 CDI75784.1 - 0.4 10.3 10.1 0.73 9.5 7.0 1.6 1 1 0 1 1 1 0 TMEM154 protein family FAM176 PF14851.1 CDI75784.1 - 0.44 10.2 3.0 0.53 9.9 2.1 1.2 1 0 0 1 1 1 0 FAM176 family PAT1 PF09770.4 CDI75784.1 - 0.46 8.6 22.1 0.44 8.7 15.3 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 OATP PF03137.15 CDI75784.1 - 0.54 8.2 2.8 0.52 8.2 1.9 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family DUF2572 PF10833.3 CDI75784.1 - 0.59 9.5 8.0 0.72 9.2 5.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2572) Pex16 PF08610.5 CDI75784.1 - 0.74 8.7 8.0 0.86 8.5 5.5 1.1 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) TFIIA PF03153.8 CDI75784.1 - 1 9.2 19.5 0.98 9.2 13.5 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit EphA2_TM PF14575.1 CDI75784.1 - 1.2 9.6 5.8 1.6 9.1 4.0 1.5 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain AAA_23 PF13476.1 CDI75784.1 - 1.3 9.3 10.8 1.4 9.2 7.5 1.1 1 0 0 1 1 1 0 AAA domain MscS_TM PF12794.2 CDI75784.1 - 1.3 7.5 4.0 1.3 7.5 2.7 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 Kei1 PF08552.6 CDI75784.1 - 1.4 8.5 4.4 1.6 8.3 3.0 1.2 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 DUF2232 PF09991.4 CDI75784.1 - 1.4 7.8 4.4 1.5 7.6 3.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) EIIBC-GUT_N PF03612.9 CDI75784.1 - 1.6 8.3 5.3 2.4 7.7 3.7 1.3 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus 60KD_IMP PF02096.15 CDI75784.1 - 1.8 8.1 10.4 2.3 7.8 7.2 1.3 1 0 0 1 1 1 0 60Kd inner membrane protein DUF4557 PF15101.1 CDI75784.1 - 1.9 8.3 16.3 2.7 7.7 11.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) Rpp20 PF12328.3 CDI75784.1 - 3.5 7.2 7.5 5.3 6.6 5.2 1.2 1 0 0 1 1 1 0 Rpp20 subunit of nuclear RNase MRP and P RED_N PF07808.8 CDI75784.1 - 4 6.5 15.2 4.9 6.3 10.5 1.1 1 0 0 1 1 1 0 RED-like protein N-terminal region DUF4175 PF13779.1 CDI75784.1 - 5.8 4.4 29.3 8.2 3.9 20.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) DUF788 PF05620.6 CDI75784.1 - 6.3 6.6 10.4 8.9 6.1 7.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF788) YjgP_YjgQ PF03739.9 CDI75785.1 - 0.0054 15.5 0.4 0.0078 14.9 0.3 1.2 1 0 0 1 1 1 1 Predicted permease YjgP/YjgQ family Macoilin PF09726.4 CDI75785.1 - 0.047 11.9 15.9 0.061 11.6 11.0 1.0 1 0 0 1 1 1 0 Transmembrane protein SAPS PF04499.10 CDI75785.1 - 0.052 12.1 8.2 0.059 11.9 5.7 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein UNC-79 PF14776.1 CDI75785.1 - 0.12 10.7 4.2 0.16 10.3 2.9 1.1 1 0 0 1 1 1 0 Cation-channel complex subunit UNC-79 Ycf1 PF05758.7 CDI75785.1 - 0.12 10.0 7.4 0.13 9.9 5.1 1.0 1 0 0 1 1 1 0 Ycf1 Ndc1_Nup PF09531.5 CDI75785.1 - 0.15 10.4 9.2 0.18 10.1 6.4 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Orbi_VP6 PF01516.11 CDI75785.1 - 0.16 10.9 4.1 0.19 10.7 2.8 1.1 1 0 0 1 1 1 0 Orbivirus helicase VP6 Spc7_N PF15402.1 CDI75785.1 - 0.26 9.2 17.0 0.33 8.9 11.8 1.1 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 SpoIIIAH PF12685.2 CDI75785.1 - 0.39 10.1 20.5 0.54 9.7 14.2 1.1 1 0 0 1 1 1 0 SpoIIIAH-like protein Otopetrin PF03189.8 CDI75785.1 - 0.41 9.5 2.5 0.46 9.4 1.8 1.1 1 0 0 1 1 1 0 Otopetrin Plasmodium_Vir PF05795.6 CDI75785.1 - 0.53 9.4 3.8 0.68 9.0 2.7 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein DUF966 PF06136.8 CDI75785.1 - 0.57 9.5 17.2 0.71 9.2 11.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF966) PTS_EIIC PF02378.13 CDI75785.1 - 0.62 8.8 5.7 0.93 8.2 4.0 1.3 1 0 0 1 1 1 0 Phosphotransferase system, EIIC FimP PF09766.4 CDI75785.1 - 1.1 8.1 23.6 1.5 7.7 16.4 1.1 1 0 0 1 1 1 0 Fms-interacting protein GOLD_2 PF13897.1 CDI75785.1 - 1.3 9.2 5.5 2 8.6 3.8 1.3 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking Sugar_tr PF00083.19 CDI75785.1 - 1.3 7.5 15.6 0.0051 15.4 1.9 2.6 2 1 1 3 3 3 0 Sugar (and other) transporter PLRV_ORF5 PF01690.12 CDI75785.1 - 1.4 8.0 18.1 1.8 7.6 12.5 1.0 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein DUF572 PF04502.8 CDI75785.1 - 1.7 7.7 18.4 2.4 7.2 12.7 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Peptidase_S49_N PF08496.5 CDI75785.1 - 2 8.1 10.9 3.6 7.3 7.6 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal G-alpha PF00503.15 CDI75785.1 - 2.6 6.6 14.0 11 4.6 7.6 2.0 2 0 0 2 2 2 0 G-protein alpha subunit RED_N PF07808.8 CDI75785.1 - 2.7 7.1 21.5 5.1 6.2 14.9 1.4 1 0 0 1 1 1 0 RED-like protein N-terminal region DUF912 PF06024.7 CDI75785.1 - 3 7.9 6.8 8.1 6.5 4.7 1.7 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) LCD1 PF09798.4 CDI75785.1 - 3.4 5.5 14.5 4.3 5.2 10.1 1.3 1 0 0 1 1 1 0 DNA damage checkpoint protein Hid1 PF12722.2 CDI75785.1 - 3.8 5.0 15.8 4 5.0 10.9 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF4045 PF13254.1 CDI75785.1 - 5.5 6.1 17.0 8.5 5.5 11.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) FAM176 PF14851.1 CDI75785.1 - 6.3 6.4 11.1 1.8 8.2 4.3 2.3 2 0 0 2 2 2 0 FAM176 family MFS_1 PF07690.11 CDI75785.1 - 6.5 5.3 23.5 0.95 8.1 8.0 2.4 1 1 1 2 2 2 0 Major Facilitator Superfamily HD-ZIP_N PF04618.7 CDI75785.1 - 6.6 7.3 12.5 0.43 11.1 3.5 2.1 1 1 1 2 2 2 0 HD-ZIP protein N terminus Bud13 PF09736.4 CDI75785.1 - 6.9 6.9 19.2 12 6.1 13.3 1.3 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex DUF106 PF01956.11 CDI75785.1 - 7.8 6.0 9.2 9.7 5.6 6.4 1.2 1 0 0 1 1 1 0 Integral membrane protein DUF106 Neur_chan_memb PF02932.11 CDI75785.1 - 9.3 6.0 10.2 14 5.4 7.1 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Herpes_DNAp_acc PF04929.7 CDI75786.1 - 0.00035 19.6 0.3 0.00035 19.6 0.2 4.0 1 1 2 3 3 3 1 Herpes DNA replication accessory factor zf-DHHC PF01529.15 CDI75787.1 - 0.21 10.9 5.9 2.6 7.3 0.4 2.3 2 0 0 2 2 2 0 DHHC palmitoyltransferase BBS2_C PF14782.1 CDI75787.1 - 4.9 5.6 25.6 0.045 12.3 2.0 2.3 1 1 1 2 2 2 0 Ciliary BBSome complex subunit 2, C-terminal DUF4024 PF13216.1 CDI75790.1 - 0.2 11.5 1.4 0.33 10.7 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4024) Asp-B-Hydro_N PF05279.6 CDI75790.1 - 2.5 7.9 52.4 3.3 7.4 36.3 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region MIP-T3 PF10243.4 CDI75790.1 - 3 6.2 76.1 3.8 5.8 52.8 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Utp14 PF04615.8 CDI75790.1 - 6.3 4.8 70.9 8 4.4 49.1 1.0 1 0 0 1 1 1 0 Utp14 protein SR-25 PF10500.4 CDI75791.1 - 0.65 9.4 51.2 0.25 10.8 18.9 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Neur_chan_memb PF02932.11 CDI75791.1 - 2.8 7.7 14.7 0.28 11.0 6.7 1.8 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Zip PF02535.17 CDI75791.1 - 4.2 6.2 6.9 36 3.2 4.8 2.0 1 1 0 1 1 1 0 ZIP Zinc transporter FAM60A PF15396.1 CDI75791.1 - 4.2 7.0 20.7 3 7.5 10.9 2.2 2 0 0 2 2 2 0 Protein Family FAM60A DUF1427 PF07235.6 CDI75791.1 - 9.5 6.3 9.7 0.32 11.1 0.2 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1427) NAM PF02365.10 CDI75792.1 - 0.078 13.1 0.2 0.078 13.1 0.1 3.4 4 0 0 4 4 4 0 No apical meristem (NAM) protein MIP-T3 PF10243.4 CDI75793.1 - 3.7 5.8 74.5 4.3 5.6 51.6 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 BAF1_ABF1 PF04684.8 CDI75794.1 - 0.0083 15.0 18.4 0.0083 15.0 12.8 6.0 3 2 3 6 6 6 1 BAF1 / ABF1 chromatin reorganising factor PCEMA1 PF07418.6 CDI75794.1 - 0.94 8.7 21.9 0.13 11.5 9.9 2.4 2 0 0 2 2 2 0 Acidic phosphoprotein precursor PCEMA1 Nramp PF01566.13 CDI75797.1 - 0.024 13.4 0.1 0.024 13.4 0.1 1.5 1 1 1 2 2 2 0 Natural resistance-associated macrophage protein SR-25 PF10500.4 CDI75797.1 - 0.96 8.8 31.2 2.3 7.6 21.6 1.6 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein SR-25 PF10500.4 CDI75798.1 - 0.00064 19.2 3.7 0.00064 19.2 2.6 3.1 3 0 0 3 3 3 3 Nuclear RNA-splicing-associated protein CD20 PF04103.10 CDI75799.1 - 0.014 15.3 7.8 1.2 9.0 0.1 4.1 4 1 0 4 4 4 0 CD20-like family ISN1 PF06437.6 CDI75799.1 - 0.15 10.7 10.1 1.3 7.5 0.6 2.5 2 0 0 2 2 2 0 IMP-specific 5'-nucleotidase Acetyltransf_1 PF00583.19 CDI75800.1 - 0.004 17.1 0.3 0.011 15.7 0.2 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family DUF605 PF04652.11 CDI75801.1 - 1.1 8.5 30.7 1.5 8.0 21.3 1.2 1 0 0 1 1 1 0 Vta1 like TFIIA PF03153.8 CDI75801.1 - 3.1 7.6 23.3 3.8 7.3 16.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SOBP PF15279.1 CDI75801.1 - 9.8 6.4 24.6 12 6.1 17.0 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein DUF1510 PF07423.6 CDI75802.1 - 0.17 11.2 30.0 0.2 11.0 20.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) CDC45 PF02724.9 CDI75802.1 - 1.9 6.3 30.0 2.1 6.2 20.8 1.0 1 0 0 1 1 1 0 CDC45-like protein Spore_YhcN_YlaJ PF09580.5 CDI75802.1 - 5.2 7.1 31.9 7.2 6.6 22.1 1.3 1 0 0 1 1 1 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) Rtf2 PF04641.7 CDI75802.1 - 5.8 6.0 30.5 6.7 5.8 21.1 1.0 1 0 0 1 1 1 0 Rtf2 RING-finger PBP1_TM PF14812.1 CDI75803.1 - 0.052 13.8 0.7 0.052 13.8 0.5 3.9 4 0 0 4 4 4 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Nha1_C PF08619.5 CDI75803.1 - 0.3 10.3 25.3 0.06 12.6 7.7 2.2 2 0 0 2 2 2 0 Alkali metal cation/H+ antiporter Nha1 C terminus DUF966 PF06136.8 CDI75803.1 - 0.95 8.8 28.8 0.34 10.2 11.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF966) Herpes_UL87 PF03043.9 CDI75803.1 - 1.7 6.9 19.7 3.5 5.9 13.7 1.4 1 1 0 1 1 1 0 Herpesvirus UL87 family SAPS PF04499.10 CDI75803.1 - 2.4 6.7 27.6 2.7 6.5 9.2 2.1 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein Herpes_gE PF02480.11 CDI75803.1 - 5.1 5.2 9.0 1.6 6.8 3.0 2.0 2 0 0 2 2 2 0 Alphaherpesvirus glycoprotein E Hid1 PF12722.2 CDI75803.1 - 8.9 3.8 32.1 1.3 6.6 11.4 2.1 2 0 0 2 2 2 0 High-temperature-induced dauer-formation protein Carb_kinase PF01256.12 CDI75804.1 - 6.7e-20 71.3 0.0 6.7e-20 71.3 0.0 4.3 5 0 0 5 5 5 1 Carbohydrate kinase BAF1_ABF1 PF04684.8 CDI75804.1 - 0.00014 20.8 18.1 0.00014 20.8 12.6 4.1 3 1 1 4 4 4 1 BAF1 / ABF1 chromatin reorganising factor Med15 PF09606.5 CDI75804.1 - 0.0031 15.7 10.1 0.0031 15.7 7.0 3.1 3 0 0 3 3 3 2 ARC105 or Med15 subunit of Mediator complex non-fungal Spt20 PF12090.3 CDI75804.1 - 0.014 14.7 0.7 0.12 11.7 0.1 2.3 2 0 0 2 2 2 0 Spt20 family Macoilin PF09726.4 CDI75804.1 - 0.13 10.5 23.4 0.57 8.3 1.9 2.2 2 0 0 2 2 2 0 Transmembrane protein CWC25 PF12542.3 CDI75804.1 - 4.5 7.7 11.6 4.6 7.7 0.3 3.3 3 0 0 3 3 3 0 Pre-mRNA splicing factor IncA PF04156.9 CDI75805.1 - 0.00015 21.4 14.9 0.0002 21.0 10.3 1.4 1 0 0 1 1 1 1 IncA protein FimP PF09766.4 CDI75805.1 - 0.0072 15.4 23.4 0.0077 15.3 16.2 1.2 1 0 0 1 1 1 1 Fms-interacting protein Paf1 PF03985.8 CDI75805.1 - 0.092 11.4 15.4 0.08 11.6 10.7 1.2 1 0 0 1 1 1 0 Paf1 DUF1980 PF09323.5 CDI75805.1 - 0.12 12.0 11.7 0.13 11.9 8.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) SR-25 PF10500.4 CDI75805.1 - 0.18 11.2 18.2 0.21 11.0 12.6 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Folate_carrier PF01770.13 CDI75805.1 - 0.19 10.1 11.2 0.22 9.9 7.8 1.2 1 0 0 1 1 1 0 Reduced folate carrier DUF2232 PF09991.4 CDI75805.1 - 0.2 10.6 9.2 0.23 10.3 6.4 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) AAA_23 PF13476.1 CDI75805.1 - 0.22 11.7 14.1 0.2 11.9 9.7 1.1 1 0 0 1 1 1 0 AAA domain ATG22 PF11700.3 CDI75805.1 - 0.25 9.7 2.8 0.28 9.6 1.9 1.1 1 0 0 1 1 1 0 Vacuole effluxer Atg22 like GDE_N PF12439.3 CDI75805.1 - 0.53 9.4 9.9 0.54 9.4 6.8 1.2 1 0 0 1 1 1 0 Glycogen debranching enzyme N terminal PPP4R2 PF09184.6 CDI75805.1 - 0.54 9.7 11.7 0.54 9.7 8.1 1.1 1 0 0 1 1 1 0 PPP4R2 Pex16 PF08610.5 CDI75805.1 - 0.61 9.0 9.9 0.54 9.2 6.8 1.2 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) OATP PF03137.15 CDI75805.1 - 0.79 7.6 10.4 0.83 7.6 7.2 1.2 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Nucleoside_tran PF01733.13 CDI75805.1 - 0.88 8.6 5.0 0.86 8.7 3.5 1.1 1 0 0 1 1 1 0 Nucleoside transporter Hid1 PF12722.2 CDI75805.1 - 1.4 6.5 16.2 1.2 6.7 11.2 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF3801 PF12687.2 CDI75805.1 - 1.5 8.3 16.9 1.6 8.2 11.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3801) Peptidase_U57 PF05582.7 CDI75805.1 - 1.6 7.6 12.5 1.5 7.7 8.7 1.2 1 0 0 1 1 1 0 YabG peptidase U57 CD20 PF04103.10 CDI75805.1 - 1.8 8.5 11.1 4.3 7.2 7.7 1.7 1 1 0 1 1 1 0 CD20-like family TraT PF05818.7 CDI75805.1 - 1.9 7.8 22.6 2.6 7.4 15.7 1.2 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein FHIPEP PF00771.15 CDI75805.1 - 2 6.6 15.1 2.4 6.3 10.5 1.1 1 0 0 1 1 1 0 FHIPEP family Serinc PF03348.10 CDI75805.1 - 2 7.0 20.1 2.4 6.7 13.9 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) His_Phos_2 PF00328.17 CDI75805.1 - 2.3 7.4 19.6 2.8 7.1 13.6 1.1 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 2) DUF2215 PF10225.4 CDI75805.1 - 2.7 7.3 9.9 2.9 7.2 6.9 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) CDK5_activator PF03261.10 CDI75805.1 - 4.5 6.5 20.5 5.1 6.3 14.2 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein DDHD PF02862.12 CDI75805.1 - 4.5 6.9 21.3 5.3 6.7 14.8 1.2 1 0 0 1 1 1 0 DDHD domain Sec62 PF03839.11 CDI75805.1 - 4.7 6.5 10.3 4.9 6.4 7.2 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 AMP-binding PF00501.23 CDI75805.1 - 5.5 5.2 8.2 5.9 5.1 5.7 1.0 1 0 0 1 1 1 0 AMP-binding enzyme FLO_LFY PF01698.11 CDI75805.1 - 5.5 5.7 25.2 5.9 5.6 17.5 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein Raftlin PF15250.1 CDI75805.1 - 6.3 5.2 19.4 6.3 5.2 13.4 1.1 1 0 0 1 1 1 0 Raftlin Ycf1 PF05758.7 CDI75805.1 - 7.1 4.1 15.6 6.6 4.2 10.8 1.1 1 0 0 1 1 1 0 Ycf1 SID-1_RNA_chan PF13965.1 CDI75805.1 - 7.6 4.5 8.9 7.7 4.5 6.2 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Ctr PF04145.10 CDI75805.1 - 9.9 6.2 16.8 6.8 6.7 10.3 1.7 1 1 1 2 2 2 0 Ctr copper transporter family MR_MLE_C PF13378.1 CDI75807.1 - 0.57 10.1 5.0 7.2 6.6 0.9 2.4 2 0 0 2 2 2 0 Enolase C-terminal domain-like Hid1 PF12722.2 CDI75807.1 - 2.1 5.9 13.6 2.7 5.5 9.4 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein FimP PF09766.4 CDI75807.1 - 3 6.8 13.6 1 8.3 4.6 2.1 2 0 0 2 2 2 0 Fms-interacting protein DUF1510 PF07423.6 CDI75809.1 - 0.05 12.9 15.6 0.054 12.8 10.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) HCV_NS5a_C PF12941.2 CDI75809.1 - 0.17 11.4 4.1 0.18 11.3 2.9 1.1 1 0 0 1 1 1 0 HCV NS5a protein C-terminal region FHIPEP PF00771.15 CDI75809.1 - 0.29 9.4 8.9 0.34 9.1 6.2 1.1 1 0 0 1 1 1 0 FHIPEP family UPF0565 PF10561.4 CDI75809.1 - 0.3 9.9 12.1 0.32 9.8 8.4 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0565 PH_4 PF15404.1 CDI75809.1 - 0.38 10.2 12.2 0.44 10.0 8.4 1.3 1 0 0 1 1 1 0 Pleckstrin homology domain Spore_coat_CotO PF14153.1 CDI75809.1 - 0.64 9.4 25.2 0.66 9.3 17.5 1.1 1 0 0 1 1 1 0 Spore coat protein CotO FYDLN_acid PF09538.5 CDI75809.1 - 0.65 10.6 6.9 0.73 10.4 4.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) DUF3984 PF13136.1 CDI75809.1 - 0.72 9.0 12.8 0.82 8.8 8.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3984) RED_N PF07808.8 CDI75809.1 - 0.77 8.9 24.5 0.93 8.6 17.0 1.3 1 0 0 1 1 1 0 RED-like protein N-terminal region MRP-S26 PF14943.1 CDI75809.1 - 0.94 9.0 18.6 1 8.9 12.9 1.1 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 Hom_end_hint PF05203.11 CDI75809.1 - 0.98 9.1 13.9 1 9.0 9.7 1.0 1 0 0 1 1 1 0 Hom_end-associated Hint Paf1 PF03985.8 CDI75809.1 - 1.2 7.8 24.2 1.2 7.8 16.8 1.0 1 0 0 1 1 1 0 Paf1 Peptidase_U57 PF05582.7 CDI75809.1 - 1.2 8.0 14.2 1.2 8.0 9.9 1.0 1 0 0 1 1 1 0 YabG peptidase U57 Peptidase_S49_N PF08496.5 CDI75809.1 - 1.3 8.8 15.5 1.4 8.7 10.8 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF3381 PF11861.3 CDI75809.1 - 1.3 8.4 17.1 1.3 8.4 11.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) Gti1_Pac2 PF09729.4 CDI75809.1 - 1.3 8.8 12.5 1.4 8.7 8.7 1.2 1 0 0 1 1 1 0 Gti1/Pac2 family AIF_C PF14721.1 CDI75809.1 - 1.5 9.0 15.4 1.8 8.8 10.7 1.1 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term CDC45 PF02724.9 CDI75809.1 - 1.7 6.6 15.2 1.7 6.6 10.5 1.0 1 0 0 1 1 1 0 CDC45-like protein Tim54 PF11711.3 CDI75809.1 - 1.7 7.1 12.9 1.8 7.0 9.0 1.0 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DUF3306 PF11748.3 CDI75809.1 - 1.8 9.2 15.5 2.4 8.8 10.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3306) RR_TM4-6 PF06459.7 CDI75809.1 - 1.9 8.3 19.3 2.1 8.1 13.4 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 RNA_pol_Rpc4 PF05132.9 CDI75809.1 - 1.9 8.4 17.0 2.3 8.2 11.8 1.2 1 0 0 1 1 1 0 RNA polymerase III RPC4 GOLD_2 PF13897.1 CDI75809.1 - 2.1 8.5 6.9 2.4 8.3 4.8 1.3 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking Band_3_cyto PF07565.8 CDI75809.1 - 2.1 7.8 20.4 2 7.8 14.2 1.0 1 0 0 1 1 1 0 Band 3 cytoplasmic domain DDHD PF02862.12 CDI75809.1 - 2.2 8.0 17.7 2.4 7.9 12.3 1.1 1 0 0 1 1 1 0 DDHD domain SprA-related PF12118.3 CDI75809.1 - 2.2 7.5 42.1 2.4 7.4 29.1 1.1 1 0 0 1 1 1 0 SprA-related family NARP1 PF12569.3 CDI75809.1 - 2.2 6.9 18.5 2.4 6.8 12.8 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Baculo_PP31 PF05311.6 CDI75809.1 - 2.4 7.3 19.1 2.6 7.2 13.2 1.1 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) Pal1 PF08316.6 CDI75809.1 - 2.6 8.4 9.3 2.8 8.3 6.4 1.1 1 0 0 1 1 1 0 Pal1 cell morphology protein DUF4557 PF15101.1 CDI75809.1 - 2.6 7.8 31.0 3.2 7.5 21.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) FLO_LFY PF01698.11 CDI75809.1 - 2.7 6.7 20.0 2.7 6.7 13.8 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein N6_N4_Mtase PF01555.13 CDI75809.1 - 2.8 7.3 8.3 3.4 7.1 5.8 1.2 1 0 0 1 1 1 0 DNA methylase DUF1266 PF06889.6 CDI75809.1 - 2.8 7.7 12.6 2.9 7.6 8.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1266) FAM60A PF15396.1 CDI75809.1 - 3.4 7.3 14.2 3.8 7.2 9.8 1.1 1 0 0 1 1 1 0 Protein Family FAM60A Dala_Dala_lig_N PF01820.16 CDI75809.1 - 3.5 7.9 10.2 4.9 7.4 7.1 1.3 1 0 0 1 1 1 0 D-ala D-ala ligase N-terminus Med19 PF10278.4 CDI75809.1 - 3.8 7.1 13.6 4 7.0 9.4 1.1 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 Herpes_DNAp_acc PF04929.7 CDI75809.1 - 3.8 6.3 15.4 4 6.2 10.7 1.0 1 0 0 1 1 1 0 Herpes DNA replication accessory factor SpoIIP PF07454.6 CDI75809.1 - 4.1 6.5 15.3 4.5 6.3 10.6 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) DUF2072 PF09845.4 CDI75809.1 - 4.1 7.3 11.3 4.6 7.1 7.8 1.1 1 0 0 1 1 1 0 Zn-ribbon containing protein (DUF2072) Mem_trans PF03547.13 CDI75809.1 - 4.5 5.4 8.6 4.8 5.3 6.0 1.0 1 0 0 1 1 1 0 Membrane transport protein DUF4175 PF13779.1 CDI75809.1 - 4.8 4.7 53.0 4.4 4.8 36.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Dynamin_N PF00350.18 CDI75809.1 - 5 6.9 11.9 5.8 6.7 8.3 1.1 1 0 0 1 1 1 0 Dynamin family Serinc PF03348.10 CDI75809.1 - 5.3 5.6 17.3 5.4 5.6 12.0 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) Herpes_env PF01673.13 CDI75809.1 - 5.4 5.4 12.2 5.6 5.3 8.4 1.0 1 0 0 1 1 1 0 Herpesvirus putative major envelope glycoprotein PPP4R2 PF09184.6 CDI75809.1 - 5.4 6.4 16.1 5.2 6.5 11.1 1.0 1 0 0 1 1 1 0 PPP4R2 Raftlin PF15250.1 CDI75809.1 - 5.6 5.3 18.6 5.9 5.2 12.9 1.0 1 0 0 1 1 1 0 Raftlin DUF3260 PF11658.3 CDI75809.1 - 5.7 4.9 16.0 6.4 4.7 11.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3260) DUF4045 PF13254.1 CDI75809.1 - 5.7 6.1 18.0 6 6.0 12.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) EIIBC-GUT_N PF03612.9 CDI75809.1 - 5.8 6.4 14.0 7.8 6.0 9.7 1.3 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus AUX_IAA PF02309.11 CDI75809.1 - 5.9 6.5 16.6 6.5 6.4 11.5 1.1 1 0 0 1 1 1 0 AUX/IAA family DUF2203 PF09969.4 CDI75809.1 - 6 7.1 12.7 7 6.8 8.8 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) RIC3 PF15361.1 CDI75809.1 - 6.1 7.0 18.8 7.5 6.7 13.0 1.3 1 0 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 DUF4512 PF14975.1 CDI75809.1 - 6.2 7.7 11.9 7.3 7.4 8.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4512) NPR3 PF03666.8 CDI75809.1 - 6.2 5.2 17.4 6.5 5.1 12.1 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 FAM176 PF14851.1 CDI75809.1 - 6.5 6.4 10.8 8.8 5.9 7.5 1.2 1 0 0 1 1 1 0 FAM176 family Zip PF02535.17 CDI75809.1 - 6.6 5.6 10.1 6.5 5.6 7.0 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter CPSF100_C PF13299.1 CDI75809.1 - 6.8 6.8 17.2 7.3 6.7 11.9 1.1 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal DUF2828 PF11443.3 CDI75809.1 - 7 4.7 13.7 7.5 4.6 9.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Rtf2 PF04641.7 CDI75809.1 - 7.2 5.7 18.6 8.5 5.4 12.9 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger Hid1 PF12722.2 CDI75809.1 - 7.2 4.1 20.6 6.9 4.2 14.3 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF2201_N PF13203.1 CDI75809.1 - 7.6 5.6 20.0 7.3 5.6 13.9 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain Maf1 PF09174.5 CDI75809.1 - 7.6 6.3 10.6 8.6 6.1 7.4 1.2 1 0 0 1 1 1 0 Maf1 regulator RNA_pol_Rpb1_5 PF04998.12 CDI75809.1 - 8.5 5.5 11.9 9.1 5.4 8.2 1.0 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 FNIP_N PF14636.1 CDI75809.1 - 8.7 6.8 19.7 10 6.5 13.6 1.1 1 0 0 1 1 1 0 Folliculin-interacting protein N-terminus HGTP_anticodon2 PF12745.2 CDI75809.1 - 9.5 5.2 17.6 11 5.1 12.2 1.1 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs TraH_2 PF06871.6 CDI75809.1 - 9.6 5.5 8.8 11 5.3 6.1 1.2 1 0 0 1 1 1 0 TraH_2 DHHW PF14286.1 CDI75809.1 - 9.7 5.3 14.8 9.3 5.4 10.3 1.0 1 0 0 1 1 1 0 DHHW protein CAF-1_p150 PF11600.3 CDI75811.1 - 0.0077 15.6 43.9 0.011 15.1 30.5 1.2 1 0 0 1 1 1 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal RAP1 PF07218.6 CDI75811.1 - 0.0091 14.1 10.3 0.01 13.9 7.1 1.0 1 0 0 1 1 1 1 Rhoptry-associated protein 1 (RAP-1) SprA-related PF12118.3 CDI75811.1 - 0.11 11.8 70.7 0.15 11.3 49.0 1.2 1 0 0 1 1 1 0 SprA-related family Plasmodium_Vir PF05795.6 CDI75813.1 - 0.38 9.9 4.4 0.54 9.4 3.0 1.3 1 0 0 1 1 1 0 Plasmodium vivax Vir protein PH PF00169.24 CDI75814.1 - 6.3e-09 35.9 0.0 4.9e-05 23.4 0.0 3.3 2 1 1 3 3 3 3 PH domain Nop14 PF04147.7 CDI75814.1 - 0.14 10.0 26.9 0.19 9.6 18.6 1.1 1 0 0 1 1 1 0 Nop14-like family Utp14 PF04615.8 CDI75814.1 - 5.1 5.1 8.4 7.6 4.5 5.9 1.2 1 0 0 1 1 1 0 Utp14 protein Daxx PF03344.10 CDI75814.1 - 8.7 4.6 21.7 14 4.0 15.1 1.2 1 0 0 1 1 1 0 Daxx Family DKCLD PF08068.7 CDI75815.1 - 2.3e-26 91.4 0.0 3.5e-26 90.9 0.0 1.3 1 0 0 1 1 1 1 DKCLD (NUC011) domain TruB_N PF01509.13 CDI75815.1 - 2.4e-12 47.2 0.2 3e-12 46.9 0.1 1.1 1 0 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) Kinesin PF00225.18 CDI75816.1 - 1.8e-104 349.0 0.0 2.4e-104 348.6 0.0 1.1 1 0 0 1 1 1 1 Kinesin motor domain DUF1049 PF06305.6 CDI75818.1 - 0.0042 16.5 3.6 0.0042 16.5 2.5 7.0 7 0 0 7 7 3 1 Protein of unknown function (DUF1049) Conotoxin PF02950.12 CDI75818.1 - 0.0076 17.0 1.9 0.0076 17.0 1.3 7.3 6 1 1 7 7 6 1 Conotoxin DUF2681 PF10883.3 CDI75818.1 - 0.014 15.5 7.8 0.014 15.5 5.4 7.9 7 1 1 8 8 6 0 Protein of unknown function (DUF2681) Ctr PF04145.10 CDI75818.1 - 0.018 15.0 0.8 0.018 15.0 0.5 6.3 3 3 1 4 4 2 0 Ctr copper transporter family Cytochrom_B_N PF00033.14 CDI75818.1 - 0.02 14.2 0.2 0.96 8.7 0.0 3.3 3 0 0 3 3 3 0 Cytochrome b(N-terminal)/b6/petB SpoIIIAH PF12685.2 CDI75818.1 - 0.052 13.0 0.1 0.052 13.0 0.0 6.1 2 2 1 4 4 1 0 SpoIIIAH-like protein EphA2_TM PF14575.1 CDI75818.1 - 0.065 13.6 0.1 0.065 13.6 0.1 7.0 6 1 1 7 7 6 0 Ephrin type-A receptor 2 transmembrane domain TMEM154 PF15102.1 CDI75818.1 - 0.08 12.6 0.3 0.08 12.6 0.2 6.7 7 1 1 8 8 8 0 TMEM154 protein family DUF3357 PF11837.3 CDI75818.1 - 0.12 12.2 0.0 0.12 12.2 0.0 6.6 6 2 1 7 7 7 0 Domain of unknown function (DUF3357) 7tm_1 PF00001.16 CDI75818.1 - 0.14 11.2 0.0 0.14 11.2 0.0 4.2 3 2 0 3 3 1 0 7 transmembrane receptor (rhodopsin family) Pex24p PF06398.6 CDI75818.1 - 0.19 10.4 0.3 1.1 7.9 0.0 2.3 2 0 0 2 2 2 0 Integral peroxisomal membrane peroxin OSTbeta PF15048.1 CDI75818.1 - 0.32 11.0 0.1 0.32 11.0 0.1 5.3 6 1 0 6 6 4 0 Organic solute transporter subunit beta protein DUF1510 PF07423.6 CDI75818.1 - 0.4 10.0 0.0 0.13 11.5 6.9 5.2 5 1 1 6 6 6 0 Protein of unknown function (DUF1510) Dpy19 PF10034.4 CDI75818.1 - 0.92 7.5 0.0 0.92 7.5 0.0 2.7 2 1 0 2 2 1 0 Q-cell neuroblast polarisation DUF2149 PF09919.4 CDI75818.1 - 1.2 9.2 0.0 1.2 9.2 0.0 5.4 6 1 0 6 6 5 0 Uncharacterized conserved protein (DUF2149) SID-1_RNA_chan PF13965.1 CDI75818.1 - 1.3 7.0 0.0 1.3 7.0 0.0 3.2 4 0 0 4 4 4 0 dsRNA-gated channel SID-1 CD20 PF04103.10 CDI75818.1 - 3 7.7 0.0 3 7.7 0.0 6.6 5 2 0 6 6 5 0 CD20-like family Ycf1 PF05758.7 CDI75818.1 - 6.6 4.3 26.5 3.1 5.4 9.5 3.3 3 0 0 3 3 3 0 Ycf1 FimP PF09766.4 CDI75819.1 - 0.0054 15.8 6.3 0.0054 15.8 4.3 1.0 1 0 0 1 1 1 1 Fms-interacting protein TRAP_alpha PF03896.11 CDI75819.1 - 0.022 13.7 14.7 0.027 13.4 10.2 1.0 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Rrp15p PF07890.7 CDI75819.1 - 0.14 12.2 10.5 0.17 11.9 7.3 1.1 1 0 0 1 1 1 0 Rrp15p DHHW PF14286.1 CDI75819.1 - 0.39 9.9 9.6 0.39 9.9 6.6 1.0 1 0 0 1 1 1 0 DHHW protein DUF1510 PF07423.6 CDI75819.1 - 0.4 10.0 20.6 0.4 10.0 14.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Spore_coat_CotO PF14153.1 CDI75819.1 - 0.41 10.0 21.6 0.44 9.9 15.0 1.1 1 0 0 1 1 1 0 Spore coat protein CotO Tim54 PF11711.3 CDI75819.1 - 0.43 9.1 12.7 0.42 9.1 8.8 1.0 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 TLP-20 PF06088.6 CDI75819.1 - 0.51 10.0 7.9 0.57 9.8 5.5 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) PPP4R2 PF09184.6 CDI75819.1 - 0.91 9.0 24.5 1 8.8 17.0 1.1 1 0 0 1 1 1 0 PPP4R2 RNA_pol_3_Rpc31 PF11705.3 CDI75819.1 - 1.2 9.0 23.2 1.5 8.6 16.1 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Serinc PF03348.10 CDI75819.1 - 1.3 7.6 5.4 1.5 7.4 3.7 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) NOA36 PF06524.7 CDI75819.1 - 1.4 8.1 11.0 1.4 8.0 7.6 1.1 1 0 0 1 1 1 0 NOA36 protein Vfa1 PF08432.5 CDI75819.1 - 1.4 8.8 15.2 1.5 8.8 10.5 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF4557 PF15101.1 CDI75819.1 - 1.6 8.5 4.5 1.6 8.5 3.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) PRTP PF01366.13 CDI75819.1 - 1.7 6.5 6.9 1.7 6.5 4.8 1.0 1 0 0 1 1 1 0 Herpesvirus processing and transport protein FYDLN_acid PF09538.5 CDI75819.1 - 1.8 9.1 17.6 2.5 8.7 12.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) Daxx PF03344.10 CDI75819.1 - 2 6.7 27.9 2.1 6.7 19.4 1.0 1 0 0 1 1 1 0 Daxx Family RR_TM4-6 PF06459.7 CDI75819.1 - 3.4 7.4 21.0 3.8 7.3 14.6 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF4512 PF14975.1 CDI75819.1 - 4.2 8.2 5.3 5.5 7.8 3.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4512) Zip PF02535.17 CDI75819.1 - 4.9 6.0 7.7 5.4 5.9 5.3 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter DDHD PF02862.12 CDI75819.1 - 5 6.8 12.1 5.1 6.8 8.4 1.1 1 0 0 1 1 1 0 DDHD domain SspB PF04386.8 CDI75819.1 - 5 6.7 13.0 6.7 6.2 9.0 1.3 1 0 0 1 1 1 0 Stringent starvation protein B RNA_polI_A34 PF08208.6 CDI75819.1 - 5.2 6.6 19.1 5.8 6.5 13.3 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Ycf1 PF05758.7 CDI75819.1 - 5.5 4.5 14.9 5.1 4.6 10.3 1.0 1 0 0 1 1 1 0 Ycf1 DUF913 PF06025.7 CDI75819.1 - 7.5 5.1 7.9 8.4 5.0 5.5 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) CDC45 PF02724.9 CDI75819.1 - 8.2 4.3 19.4 8.1 4.3 13.4 1.0 1 0 0 1 1 1 0 CDC45-like protein Raftlin PF15250.1 CDI75819.1 - 8.7 4.7 9.3 8.6 4.7 6.5 1.0 1 0 0 1 1 1 0 Raftlin TraH_2 PF06871.6 CDI75819.1 - 9 5.6 8.1 9.9 5.5 5.6 1.1 1 0 0 1 1 1 0 TraH_2 CENP-T PF15511.1 CDI75819.1 - 9.1 5.4 18.4 10 5.2 12.8 1.0 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T SR-25 PF10500.4 CDI75821.1 - 7.1e-06 25.6 18.3 7.1e-06 25.6 12.7 2.1 2 0 0 2 2 2 2 Nuclear RNA-splicing-associated protein CAF-1_p150 PF11600.3 CDI75821.1 - 0.74 9.1 33.2 0.1 11.9 14.1 2.2 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal SAGA-Tad1 PF12767.2 CDI75821.1 - 9.4 5.8 23.1 1.1 8.8 9.5 2.2 2 0 0 2 2 2 0 Transcriptional regulator of RNA polII, SAGA, subunit IncA PF04156.9 CDI75824.1 - 0.063 12.8 8.5 0.079 12.5 5.9 1.2 1 0 0 1 1 1 0 IncA protein Nop14 PF04147.7 CDI75824.1 - 0.067 11.1 39.5 0.075 10.9 27.4 1.0 1 0 0 1 1 1 0 Nop14-like family MIP-T3 PF10243.4 CDI75824.1 - 0.12 10.8 29.7 0.13 10.7 20.6 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Spore_coat_CotO PF14153.1 CDI75824.1 - 0.25 10.7 31.2 0.29 10.5 21.6 1.1 1 0 0 1 1 1 0 Spore coat protein CotO DUF1510 PF07423.6 CDI75824.1 - 0.31 10.3 35.0 0.38 10.0 24.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) CKAP2_C PF15297.1 CDI75824.1 - 0.45 9.2 22.1 0.54 9.0 15.3 1.1 1 0 0 1 1 1 0 Cytoskeleton-associated protein 2 C-terminus LMBR1 PF04791.11 CDI75824.1 - 0.64 8.5 2.4 0.62 8.5 1.7 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein DHHW PF14286.1 CDI75824.1 - 0.65 9.2 17.0 0.74 9.0 11.8 1.0 1 0 0 1 1 1 0 DHHW protein SDA1 PF05285.7 CDI75824.1 - 0.76 8.9 37.3 0.88 8.7 25.8 1.0 1 0 0 1 1 1 0 SDA1 Med12-LCEWAV PF12145.3 CDI75824.1 - 0.87 7.9 8.1 0.98 7.8 5.6 1.0 1 0 0 1 1 1 0 Eukaryotic Mediator 12 subunit domain CENP-T PF15511.1 CDI75824.1 - 0.91 8.7 25.7 1.1 8.4 17.8 1.0 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T DUF4045 PF13254.1 CDI75824.1 - 0.97 8.6 16.3 1 8.5 11.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) CDC45 PF02724.9 CDI75824.1 - 1.1 7.2 30.2 1.2 7.0 20.9 1.0 1 0 0 1 1 1 0 CDC45-like protein Vfa1 PF08432.5 CDI75824.1 - 1.4 8.9 25.4 1.7 8.6 17.6 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Mpp10 PF04006.7 CDI75824.1 - 1.4 7.1 41.5 1.8 6.8 28.8 1.0 1 0 0 1 1 1 0 Mpp10 protein Merozoite_SPAM PF07133.6 CDI75824.1 - 1.6 8.5 54.6 2.3 8.1 37.9 1.3 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) Hid1 PF12722.2 CDI75824.1 - 1.9 6.0 12.6 2.1 5.9 8.7 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein FAM60A PF15396.1 CDI75824.1 - 2.3 7.9 5.2 2.8 7.6 3.6 1.1 1 0 0 1 1 1 0 Protein Family FAM60A AvrE PF11725.3 CDI75824.1 - 2.4 5.0 10.3 2.7 4.9 7.2 1.0 1 0 0 1 1 1 0 Pathogenicity factor YqfQ PF14181.1 CDI75824.1 - 2.5 8.1 29.2 19 5.2 20.3 2.0 1 1 0 1 1 1 0 YqfQ-like protein Daxx PF03344.10 CDI75824.1 - 2.5 6.4 43.5 3.3 6.1 30.1 1.1 1 0 0 1 1 1 0 Daxx Family RR_TM4-6 PF06459.7 CDI75824.1 - 3.2 7.5 28.4 3.9 7.2 19.7 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Raftlin PF15250.1 CDI75824.1 - 3.7 5.9 17.6 4.2 5.7 12.2 1.0 1 0 0 1 1 1 0 Raftlin Ycf1 PF05758.7 CDI75824.1 - 5 4.7 24.5 5.5 4.5 17.0 1.0 1 0 0 1 1 1 0 Ycf1 Drc1-Sld2 PF11719.3 CDI75824.1 - 6 5.8 24.3 8.5 5.3 16.9 1.2 1 0 0 1 1 1 0 DNA replication and checkpoint protein DUF913 PF06025.7 CDI75824.1 - 6.5 5.3 8.7 8.4 5.0 6.0 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Pilt PF15453.1 CDI75824.1 - 7.6 6.1 19.7 9.2 5.8 13.6 1.1 1 0 0 1 1 1 0 Protein incorporated later into Tight Junctions PLRV_ORF5 PF01690.12 CDI75824.1 - 9.1 5.2 17.0 10 5.1 11.8 1.0 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Zip PF02535.17 CDI75824.1 - 9.2 5.1 12.4 12 4.8 8.6 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Neur_chan_memb PF02932.11 CDI75824.1 - 10 5.9 7.2 12 5.7 5.0 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region rve PF00665.21 CDI75825.1 - 9.5e-20 70.9 0.0 2.6e-19 69.5 0.0 1.8 2 0 0 2 2 2 1 Integrase core domain RVT_1 PF00078.22 CDI75825.1 - 3.8e-07 29.6 0.0 6.6e-07 28.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.18 CDI75826.1 - 1.6e-05 24.6 10.0 3e-05 23.7 3.6 2.4 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_2 PF13696.1 CDI75826.1 - 0.33 10.4 2.1 0.6 9.6 1.4 1.4 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_4 PF14392.1 CDI75826.1 - 7.4 6.3 6.6 0.49 10.1 1.1 1.7 2 0 0 2 2 2 0 Zinc knuckle Pkinase PF00069.20 CDI75827.1 - 2.2e-07 30.3 0.7 3.7e-07 29.5 0.1 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDI75827.1 - 7.2e-06 25.2 0.0 1.5e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_1 PF00036.27 CDI75828.1 - 7.9e-14 49.8 0.4 8.7e-06 24.6 0.1 3.0 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.1 CDI75828.1 - 2.7e-12 46.6 0.0 6.4e-12 45.4 0.0 1.6 1 1 0 1 1 1 1 EF-hand domain pair Pkinase PF00069.20 CDI75828.1 - 1.9e-10 40.3 0.0 6e-10 38.7 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain EF-hand_6 PF13405.1 CDI75828.1 - 3.9e-08 32.5 0.4 0.0054 16.5 0.0 3.0 3 0 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.1 CDI75828.1 - 7.1e-08 31.9 0.7 0.0013 18.3 0.0 3.2 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.1 CDI75828.1 - 1.8e-07 30.1 0.5 0.028 13.7 0.0 3.2 3 0 0 3 3 3 2 EF hand DUF2267 PF10025.4 CDI75828.1 - 0.012 15.7 0.0 0.032 14.2 0.0 1.7 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2267) EF-hand_4 PF12763.2 CDI75828.1 - 0.033 13.9 0.4 0.25 11.1 0.2 2.3 1 1 1 2 2 2 0 Cytoskeletal-regulatory complex EF hand Kinase-like PF14531.1 CDI75828.1 - 0.079 11.8 0.2 0.15 11.0 0.1 1.5 1 1 1 2 2 2 0 Kinase-like Pkinase_Tyr PF07714.12 CDI75828.1 - 0.14 11.1 0.0 0.24 10.4 0.0 1.4 1 0 0 1 1 1 0 Protein tyrosine kinase SEC-C PF02810.10 CDI75829.1 - 0.0021 17.5 3.1 0.0082 15.6 2.1 2.0 1 0 0 1 1 1 1 SEC-C motif CAF-1_p150 PF11600.3 CDI75830.1 - 0.064 12.6 43.4 0.08 12.3 30.1 1.0 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal RR_TM4-6 PF06459.7 CDI75830.1 - 0.79 9.5 30.9 1.1 9.0 21.4 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SprA-related PF12118.3 CDI75830.1 - 0.94 8.7 68.8 1.4 8.1 47.7 1.2 1 0 0 1 1 1 0 SprA-related family Caldesmon PF02029.10 CDI75830.1 - 1.2 7.5 31.8 1.3 7.3 22.0 1.0 1 0 0 1 1 1 0 Caldesmon SR-25 PF10500.4 CDI75830.1 - 1.9 7.8 51.7 18 4.6 35.8 1.9 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF1510 PF07423.6 CDI75830.1 - 3.8 6.8 38.2 4.7 6.5 26.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DUF3987 PF13148.1 CDI75830.1 - 4.1 5.8 17.8 5.3 5.5 12.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) Dsh_C PF12316.3 CDI75830.1 - 5.5 7.0 32.2 6.5 6.7 22.3 1.1 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal Utp14 PF04615.8 CDI75830.1 - 6.5 4.7 41.4 7.5 4.5 28.7 1.0 1 0 0 1 1 1 0 Utp14 protein tRNA-synt_1c PF00749.16 CDI75831.1 - 4.5e-65 219.3 5.0 4.7e-34 117.4 0.0 4.7 4 1 0 4 4 4 3 tRNA synthetases class I (E and Q), catalytic domain PAT1 PF09770.4 CDI75831.1 - 0.26 9.4 21.9 0.5 8.5 15.2 1.4 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 FYDLN_acid PF09538.5 CDI75831.1 - 7.4 7.2 9.3 7 7.2 0.3 2.6 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) Med15 PF09606.5 CDI75833.1 - 0.0032 15.7 16.1 0.003 15.8 11.1 1.1 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal CAF-1_p150 PF11600.3 CDI75833.1 - 0.011 15.1 10.2 0.014 14.8 7.1 1.0 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Suf PF05843.9 CDI75833.1 - 0.013 15.2 4.9 0.013 15.2 3.4 1.0 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF3801 PF12687.2 CDI75833.1 - 0.014 14.9 2.1 0.015 14.8 1.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3801) Corona_nucleoca PF00937.13 CDI75833.1 - 0.021 13.8 7.9 0.026 13.5 5.5 1.1 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein Cwf_Cwc_15 PF04889.7 CDI75833.1 - 0.024 14.3 4.1 0.03 14.0 2.9 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Activator_LAG-3 PF11498.3 CDI75833.1 - 0.031 13.0 20.3 0.035 12.8 14.1 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 AUX_IAA PF02309.11 CDI75833.1 - 0.052 13.2 2.1 0.056 13.1 1.5 1.1 1 0 0 1 1 1 0 AUX/IAA family DUF4011 PF13195.1 CDI75833.1 - 0.071 13.1 0.6 0.082 12.9 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4011) FimP PF09766.4 CDI75833.1 - 0.25 10.3 11.8 0.27 10.2 8.2 1.1 1 0 0 1 1 1 0 Fms-interacting protein CDK2AP PF09806.4 CDI75833.1 - 0.61 10.2 10.7 0.86 9.8 7.4 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein DUF4175 PF13779.1 CDI75833.1 - 0.77 7.3 17.2 0.79 7.3 12.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) BAF1_ABF1 PF04684.8 CDI75833.1 - 1.2 7.8 18.2 1.4 7.6 12.6 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Serinc PF03348.10 CDI75833.1 - 2.7 6.6 5.6 3.1 6.3 3.9 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) IncA PF04156.9 CDI75836.1 - 0.27 10.8 17.3 0.3 10.6 12.0 1.3 1 0 0 1 1 1 0 IncA protein Bud13 PF09736.4 CDI75836.1 - 0.39 10.9 15.9 0.57 10.4 11.0 1.3 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex Ycf1 PF05758.7 CDI75836.1 - 0.41 8.3 9.3 0.46 8.1 6.5 1.0 1 0 0 1 1 1 0 Ycf1 DUF2877 PF11392.3 CDI75836.1 - 0.56 10.4 3.1 0.81 9.9 2.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2877) Med15 PF09606.5 CDI75836.1 - 0.56 8.3 40.6 0.72 7.9 28.1 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Bindin PF02084.10 CDI75836.1 - 0.62 10.0 11.3 0.057 13.4 1.4 2.0 1 1 1 2 2 2 0 Bindin DUF4175 PF13779.1 CDI75836.1 - 0.77 7.3 36.8 0.98 7.0 25.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) PAT1 PF09770.4 CDI75836.1 - 1.2 7.3 32.6 1.4 7.0 22.6 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 PIH1 PF08190.7 CDI75836.1 - 1.2 8.4 17.6 1.5 8.1 12.2 1.1 1 0 0 1 1 1 0 pre-RNA processing PIH1/Nop17 FHIPEP PF00771.15 CDI75836.1 - 2.3 6.4 6.6 2.4 6.3 4.6 1.1 1 0 0 1 1 1 0 FHIPEP family Plasmodium_Vir PF05795.6 CDI75836.1 - 2.5 7.2 7.9 3.3 6.7 5.5 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein RAP1 PF07218.6 CDI75836.1 - 7.8 4.4 9.3 8.8 4.2 6.5 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) NESP55 PF06390.7 CDI75837.1 - 1.4 8.2 19.4 1.8 7.8 13.4 1.4 1 0 0 1 1 1 0 Neuroendocrine-specific golgi protein P55 (NESP55) Sec62 PF03839.11 CDI75837.1 - 2 7.7 13.6 2 7.7 9.4 1.0 1 0 0 1 1 1 0 Translocation protein Sec62 Trypan_PARP PF05887.6 CDI75837.1 - 3.5 7.4 26.2 4.7 7.0 18.2 1.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) YqfQ PF14181.1 CDI75837.1 - 4.4 7.3 19.7 4.8 7.1 13.7 1.1 1 0 0 1 1 1 0 YqfQ-like protein MIP-T3 PF10243.4 CDI75837.1 - 4.8 5.5 28.1 4.5 5.6 19.4 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DUF2413 PF10310.4 CDI75837.1 - 5.2 5.7 15.9 5.5 5.7 11.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) SpoIIP PF07454.6 CDI75837.1 - 6.4 5.8 10.9 6.3 5.8 7.6 1.0 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Pox_Ag35 PF03286.9 CDI75837.1 - 9.8 5.6 19.2 12 5.4 13.3 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DUF755 PF05501.6 CDI75838.1 - 0.042 13.9 3.9 0.042 13.9 2.7 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF755) SR-25 PF10500.4 CDI75838.1 - 0.11 11.8 12.8 0.17 11.3 8.8 1.3 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF3628 PF12300.3 CDI75838.1 - 0.15 12.0 6.6 0.18 11.8 4.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3628) DUF4587 PF15248.1 CDI75838.1 - 0.17 12.4 14.6 0.14 12.7 1.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4587) HA2 PF04408.18 CDI75838.1 - 0.22 11.5 1.4 3.8 7.5 1.0 2.0 1 1 0 1 1 1 0 Helicase associated domain (HA2) Bot1p PF12298.3 CDI75838.1 - 0.65 9.9 8.6 0.62 9.9 5.4 1.3 1 1 0 1 1 1 0 Eukaryotic mitochondrial regulator protein FAM60A PF15396.1 CDI75838.1 - 0.77 9.4 7.9 0.88 9.2 5.5 1.1 1 0 0 1 1 1 0 Protein Family FAM60A Rtf2 PF04641.7 CDI75838.1 - 1.2 8.2 5.6 1.4 8.1 3.9 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger PALP PF00291.20 CDI75838.1 - 1.3 8.1 5.0 21 4.2 0.0 2.1 2 0 0 2 2 2 0 Pyridoxal-phosphate dependent enzyme Ribosomal_60s PF00428.14 CDI75838.1 - 1.4 9.3 15.7 7.3 7.0 6.8 2.1 2 0 0 2 2 2 0 60s Acidic ribosomal protein YscJ_FliF_C PF08345.6 CDI75838.1 - 1.7 8.6 8.6 2.1 8.3 6.0 1.3 1 0 0 1 1 1 0 Flagellar M-ring protein C-terminal G6PD_bact PF10786.4 CDI75838.1 - 2.6 7.4 6.5 6 6.2 4.5 1.7 1 1 0 1 1 1 0 Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49) CDK5_activator PF03261.10 CDI75838.1 - 4.1 6.6 7.5 4.6 6.4 5.2 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein YppG PF14179.1 CDI75838.1 - 4.4 7.9 20.7 6.6 7.3 14.3 1.4 1 0 0 1 1 1 0 YppG-like protein Suf PF05843.9 CDI75838.1 - 5.1 6.7 13.4 5.8 6.5 9.3 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Peptidase_M20 PF01546.23 CDI75839.1 - 0.045 13.2 0.4 0.072 12.5 0.3 1.3 1 0 0 1 1 1 0 Peptidase family M20/M25/M40 MCR_alpha PF02249.12 CDI75839.1 - 4.5 7.2 15.6 5.4 7.0 1.8 2.2 1 1 1 2 2 2 0 Methyl-coenzyme M reductase alpha subunit, C-terminal domain MIG-14_Wnt-bd PF06664.7 CDI75840.1 - 0.11 11.3 5.9 0.37 9.5 4.0 1.7 2 0 0 2 2 2 0 Wnt-binding factor required for Wnt secretion DUF4200 PF13863.1 CDI75841.1 - 0.027 14.4 0.7 0.05 13.5 0.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) DUF3538 PF12057.3 CDI75841.1 - 0.12 11.9 0.1 0.22 11.1 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3538) Spectrin PF00435.16 CDI75842.1 - 0.073 13.3 0.0 0.14 12.4 0.0 1.4 1 0 0 1 1 1 0 Spectrin repeat Spt20 PF12090.3 CDI75849.1 - 0.012 14.9 2.9 0.34 10.2 0.1 2.9 3 0 0 3 3 3 0 Spt20 family O-antigen_lig PF13425.1 CDI75849.1 - 1.5 8.8 7.0 3.5 7.6 4.8 1.6 1 0 0 1 1 1 0 O-antigen ligase like membrane protein Phostensin_N PF13916.1 CDI75849.1 - 3 7.8 18.0 3.9 7.5 2.4 3.7 3 0 0 3 3 3 0 PP1-regulatory protein, Phostensin N-terminal YajC PF02699.10 CDI75849.1 - 9.7 5.9 20.4 0.55 9.9 0.6 3.2 3 0 0 3 3 3 0 Preprotein translocase subunit Utp14 PF04615.8 CDI75852.1 - 0.54 8.3 42.3 0.86 7.6 29.4 1.2 1 0 0 1 1 1 0 Utp14 protein Med15 PF09606.5 CDI75852.1 - 1.6 6.7 104.6 2.4 6.2 72.5 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF2142 PF09913.4 CDI75852.1 - 2.8 6.5 6.8 5.1 5.6 4.7 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2142) SGT1 PF07093.6 CDI75852.1 - 4.9 5.4 37.1 7.2 4.8 25.7 1.2 1 0 0 1 1 1 0 SGT1 protein DUF3121 PF11319.3 CDI75853.1 - 0.016 14.7 11.2 0.018 14.5 7.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3121) Pex14_N PF04695.8 CDI75853.1 - 0.088 12.8 19.2 0.1 12.6 13.3 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Band_3_cyto PF07565.8 CDI75853.1 - 0.096 12.1 14.6 0.1 12.0 10.2 1.0 1 0 0 1 1 1 0 Band 3 cytoplasmic domain DUF4355 PF14265.1 CDI75853.1 - 0.19 11.6 22.2 0.21 11.5 15.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4355) F-protein PF00469.15 CDI75853.1 - 0.24 10.7 13.0 0.25 10.7 9.0 1.0 1 0 0 1 1 1 0 Negative factor, (F-Protein) or Nef DUF2126 PF09899.4 CDI75853.1 - 0.3 9.0 12.1 0.36 8.7 8.4 1.0 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) DUF1764 PF08576.5 CDI75853.1 - 0.41 11.4 17.6 0.62 10.8 12.2 1.3 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) CAML PF14963.1 CDI75853.1 - 0.53 9.5 3.8 0.74 9.1 2.6 1.2 1 0 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand ARF7EP_C PF14949.1 CDI75853.1 - 0.54 10.6 12.0 0.66 10.4 8.3 1.2 1 0 0 1 1 1 0 ARF7 effector protein C-terminus DUF3464 PF11947.3 CDI75853.1 - 0.59 9.5 10.8 0.65 9.4 7.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) Plasmodium_Vir PF05795.6 CDI75853.1 - 0.59 9.2 5.2 0.63 9.1 3.6 1.0 1 0 0 1 1 1 0 Plasmodium vivax Vir protein SpoIIP PF07454.6 CDI75853.1 - 0.59 9.2 12.6 0.62 9.1 8.7 1.0 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Zip PF02535.17 CDI75853.1 - 0.65 8.9 9.9 0.71 8.8 6.9 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter FLO_LFY PF01698.11 CDI75853.1 - 0.65 8.7 15.8 0.69 8.6 11.0 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein Kei1 PF08552.6 CDI75853.1 - 0.7 9.5 10.4 0.81 9.3 7.2 1.1 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 DUF702 PF05142.7 CDI75853.1 - 0.71 10.0 12.4 0.83 9.8 8.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF702) Raftlin PF15250.1 CDI75853.1 - 0.94 7.9 14.8 0.94 7.9 10.2 1.0 1 0 0 1 1 1 0 Raftlin FAM60A PF15396.1 CDI75853.1 - 1.2 8.8 12.7 1.3 8.7 8.8 1.0 1 0 0 1 1 1 0 Protein Family FAM60A Dehydrin PF00257.14 CDI75853.1 - 1.5 9.1 24.5 2 8.7 17.0 1.1 1 0 0 1 1 1 0 Dehydrin Maf1 PF09174.5 CDI75853.1 - 2 8.2 8.4 2.2 8.1 5.8 1.1 1 0 0 1 1 1 0 Maf1 regulator DUF3984 PF13136.1 CDI75853.1 - 2.1 7.4 15.5 2.3 7.3 10.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3984) CDC45 PF02724.9 CDI75853.1 - 2.3 6.1 14.2 2.4 6.0 9.9 1.0 1 0 0 1 1 1 0 CDC45-like protein DUF913 PF06025.7 CDI75853.1 - 2.4 6.8 8.6 2.3 6.8 5.9 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DHHW PF14286.1 CDI75853.1 - 2.4 7.3 12.4 2.4 7.3 8.6 1.0 1 0 0 1 1 1 0 DHHW protein UPF0560 PF10577.4 CDI75853.1 - 2.7 6.1 26.8 2.9 6.0 18.6 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 DUF4557 PF15101.1 CDI75853.1 - 2.9 7.7 27.1 3 7.6 18.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) BNR_3 PF13859.1 CDI75853.1 - 2.9 6.8 7.0 3.3 6.7 4.9 1.1 1 0 0 1 1 1 0 BNR repeat-like domain CDK5_activator PF03261.10 CDI75853.1 - 2.9 7.1 19.5 3.1 7.0 13.5 1.0 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein CPSF100_C PF13299.1 CDI75853.1 - 3.1 7.9 12.8 3.7 7.7 8.8 1.1 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal TT_ORF1 PF02956.9 CDI75853.1 - 3.4 6.0 13.8 3.3 6.0 9.5 1.0 1 0 0 1 1 1 0 TT viral orf 1 BORG_CEP PF14957.1 CDI75853.1 - 3.4 8.6 13.0 4 8.3 9.0 1.1 1 0 0 1 1 1 0 Cdc42 effector Pox_Ag35 PF03286.9 CDI75853.1 - 3.4 7.1 12.2 3.8 6.9 8.5 1.0 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Peptidase_S15 PF02129.13 CDI75853.1 - 3.7 6.8 12.5 4 6.7 8.7 1.1 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) SelP_N PF04592.9 CDI75853.1 - 3.8 6.8 19.6 4 6.7 13.6 1.0 1 0 0 1 1 1 0 Selenoprotein P, N terminal region EPL1 PF10513.4 CDI75853.1 - 4 7.6 16.4 4.2 7.5 11.4 1.1 1 0 0 1 1 1 0 Enhancer of polycomb-like APG6 PF04111.7 CDI75853.1 - 4.5 6.2 20.4 4.3 6.2 14.2 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 LIM_bind PF01803.11 CDI75853.1 - 5.2 6.0 18.0 6.3 5.8 12.5 1.1 1 0 0 1 1 1 0 LIM-domain binding protein Neur_chan_memb PF02932.11 CDI75853.1 - 5.4 6.8 12.1 5.8 6.7 8.4 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF2072 PF09845.4 CDI75853.1 - 6.1 6.7 11.8 7.9 6.4 8.2 1.2 1 0 0 1 1 1 0 Zn-ribbon containing protein (DUF2072) DUF1754 PF08555.5 CDI75853.1 - 6.2 7.4 19.2 8 7.1 13.3 1.1 1 0 0 1 1 1 0 Eukaryotic family of unknown function (DUF1754) RNA_pol_Rpb1_5 PF04998.12 CDI75853.1 - 6.5 5.9 11.2 6.7 5.8 7.8 1.0 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 FemAB PF02388.11 CDI75853.1 - 6.7 5.2 17.3 7.1 5.1 12.0 1.0 1 0 0 1 1 1 0 FemAB family FYDLN_acid PF09538.5 CDI75853.1 - 6.9 7.3 10.0 9.2 6.8 7.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) CKAP2_C PF15297.1 CDI75853.1 - 6.9 5.3 18.7 7.2 5.3 13.0 1.0 1 0 0 1 1 1 0 Cytoskeleton-associated protein 2 C-terminus RED_N PF07808.8 CDI75853.1 - 7.8 5.6 23.8 11 5.2 16.5 1.3 1 0 0 1 1 1 0 RED-like protein N-terminal region DUF822 PF05687.8 CDI75853.1 - 8.2 6.7 11.5 8.3 6.7 8.0 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF822) AUX_IAA PF02309.11 CDI75853.1 - 8.5 6.0 14.5 9.1 5.9 10.0 1.1 1 0 0 1 1 1 0 AUX/IAA family SPX PF03105.14 CDI75853.1 - 8.6 6.0 16.9 9.4 5.9 11.7 1.0 1 0 0 1 1 1 0 SPX domain DDRGK PF09756.4 CDI75853.1 - 8.8 5.6 28.4 9.6 5.5 19.7 1.1 1 0 0 1 1 1 0 DDRGK domain Mem_trans PF03547.13 CDI75853.1 - 9.2 4.4 9.6 10 4.2 6.6 1.0 1 0 0 1 1 1 0 Membrane transport protein Peptidase_U57 PF05582.7 CDI75853.1 - 9.3 5.1 15.5 10 5.0 10.7 1.1 1 0 0 1 1 1 0 YabG peptidase U57 DUF3357 PF11837.3 CDI75854.1 - 0.0034 17.2 0.4 0.15 11.9 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF3357) MIP-T3 PF10243.4 CDI75857.1 - 1e-05 24.2 27.7 1.2e-05 24.0 19.2 1.3 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 Transformer PF06495.6 CDI75857.1 - 0.019 14.8 22.4 0.022 14.6 15.5 1.2 1 0 0 1 1 1 0 Fruit fly transformer protein Claudin_2 PF13903.1 CDI75857.1 - 0.023 14.3 0.6 0.023 14.3 0.4 2.1 1 1 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction DUF1510 PF07423.6 CDI75857.1 - 0.025 13.9 20.3 0.038 13.3 14.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DUF1777 PF08648.7 CDI75857.1 - 0.041 13.6 39.3 0.05 13.3 27.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) Draxin PF15550.1 CDI75857.1 - 0.11 12.1 19.6 0.16 11.6 13.6 1.3 1 0 0 1 1 1 0 Draxin CDC45 PF02724.9 CDI75857.1 - 0.21 9.5 27.8 0.28 9.1 19.2 1.1 1 0 0 1 1 1 0 CDC45-like protein Med15 PF09606.5 CDI75857.1 - 0.23 9.6 10.9 0.33 9.1 7.5 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal SOBP PF15279.1 CDI75857.1 - 0.53 10.6 10.5 0.71 10.1 7.3 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein Asp-B-Hydro_N PF05279.6 CDI75857.1 - 0.55 10.0 22.9 0.67 9.7 15.9 1.3 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Merozoite_SPAM PF07133.6 CDI75857.1 - 0.79 9.6 23.5 1.3 8.9 16.3 1.3 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) PLRV_ORF5 PF01690.12 CDI75857.1 - 1 8.4 19.7 1.2 8.2 13.7 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Herpes_capsid PF06112.6 CDI75857.1 - 2.7 8.0 13.3 5.6 7.0 1.4 2.4 2 0 0 2 2 2 0 Gammaherpesvirus capsid protein Ycf1 PF05758.7 CDI75857.1 - 5.7 4.5 21.7 7.9 4.0 15.0 1.2 1 0 0 1 1 1 0 Ycf1 Hid1 PF12722.2 CDI75857.1 - 6.6 4.2 17.1 7 4.1 11.8 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Parvo_coat PF00740.13 CDI75857.1 - 6.6 5.5 10.7 7.3 5.4 7.4 1.2 1 0 0 1 1 1 0 Parvovirus coat protein VP2 Mem_trans PF03547.13 CDI75857.1 - 6.7 4.8 5.8 10 4.2 4.0 1.4 1 0 0 1 1 1 0 Membrane transport protein LMBR1 PF04791.11 CDI75857.1 - 7 5.1 12.9 8.8 4.7 9.0 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF1686 PF07937.6 CDI75857.1 - 7.8 6.0 7.0 1.4 8.4 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1686) Cupin_2 PF07883.6 CDI75858.1 - 0.00012 21.5 0.0 0.00024 20.5 0.0 1.5 1 0 0 1 1 1 1 Cupin domain DDRGK PF09756.4 CDI75860.1 - 0.28 10.5 12.8 0.35 10.2 8.9 1.3 1 0 0 1 1 1 0 DDRGK domain DivIC PF04977.10 CDI75860.1 - 2.7 7.5 12.1 5.9 6.4 8.4 1.6 1 0 0 1 1 1 0 Septum formation initiator PLRV_ORF5 PF01690.12 CDI75861.1 - 6.5 5.7 41.4 8.1 5.4 28.7 1.0 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Med15 PF09606.5 CDI75862.1 - 3.7e-06 25.4 152.7 8e-05 21.0 51.6 2.4 2 0 0 2 2 2 2 ARC105 or Med15 subunit of Mediator complex non-fungal Sex_peptide PF08138.6 CDI75863.1 - 0.58 10.0 1.1 11 6.0 0.2 3.4 2 0 0 2 2 2 0 Sex peptide (SP) family GYF PF02213.11 CDI75866.1 - 3e-07 29.9 0.0 3e-07 29.9 0.0 2.0 2 0 0 2 2 2 1 GYF domain CPSase_L_D2 PF02786.12 CDI75867.1 - 6.2e-19 68.1 0.2 8.1e-19 67.7 0.1 1.2 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp_4 PF13535.1 CDI75867.1 - 0.00028 20.6 0.1 0.00039 20.1 0.1 1.2 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_5 PF13549.1 CDI75867.1 - 0.0034 16.6 0.1 0.0043 16.2 0.1 1.1 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp PF02222.17 CDI75867.1 - 0.021 14.2 0.0 0.028 13.7 0.0 1.2 1 0 0 1 1 1 0 ATP-grasp domain Secretin_N_2 PF07655.8 CDI75867.1 - 0.028 14.7 23.1 0.038 14.3 16.0 1.3 1 0 0 1 1 1 0 Secretin N-terminal domain Macoilin PF09726.4 CDI75867.1 - 0.033 12.4 8.3 0.031 12.5 5.8 1.1 1 0 0 1 1 1 0 Transmembrane protein Sporozoite_P67 PF05642.6 CDI75867.1 - 0.038 11.8 3.6 0.041 11.7 2.5 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen CASP_C PF08172.7 CDI75867.1 - 0.099 11.6 3.6 0.12 11.3 2.5 1.1 1 0 0 1 1 1 0 CASP C terminal Kei1 PF08552.6 CDI75867.1 - 0.18 11.4 0.8 0.25 10.9 0.5 1.2 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 DUF4614 PF15391.1 CDI75867.1 - 0.19 11.4 6.1 0.21 11.3 4.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) SR-25 PF10500.4 CDI75867.1 - 1 8.8 14.6 1.1 8.7 10.1 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF912 PF06024.7 CDI75867.1 - 2.9 8.0 6.5 5.2 7.1 4.5 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Presenilin PF01080.12 CDI75867.1 - 3.3 6.4 5.4 3.6 6.3 3.8 1.1 1 0 0 1 1 1 0 Presenilin SprA-related PF12118.3 CDI75867.1 - 7.7 5.7 12.0 9.6 5.4 8.3 1.1 1 0 0 1 1 1 0 SprA-related family SNAP PF14938.1 CDI75868.1 - 0.016 14.4 13.1 0.024 13.7 9.1 1.4 1 1 0 1 1 1 0 Soluble NSF attachment protein, SNAP SelP_N PF04592.9 CDI75868.1 - 0.22 10.8 16.6 0.24 10.7 11.5 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region SMN PF06003.7 CDI75868.1 - 0.56 9.2 3.6 0.58 9.2 2.5 1.2 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) Zip PF02535.17 CDI75868.1 - 0.98 8.3 10.4 1 8.3 7.2 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Hid1 PF12722.2 CDI75868.1 - 1.1 6.8 21.1 1.2 6.6 14.7 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein FLO_LFY PF01698.11 CDI75868.1 - 1.3 7.8 13.8 1.3 7.7 9.6 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein Spore_YhcN_YlaJ PF09580.5 CDI75868.1 - 2.1 8.4 13.1 2 8.5 9.1 1.2 1 0 0 1 1 1 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) FAM60A PF15396.1 CDI75868.1 - 3.7 7.2 11.2 3.8 7.2 7.8 1.1 1 0 0 1 1 1 0 Protein Family FAM60A SID-1_RNA_chan PF13965.1 CDI75868.1 - 4.2 5.4 8.3 4.3 5.3 5.8 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Hom_end_hint PF05203.11 CDI75868.1 - 4.6 6.9 12.9 4.8 6.8 9.0 1.1 1 0 0 1 1 1 0 Hom_end-associated Hint Glyco_transf_15 PF01793.11 CDI75868.1 - 4.8 6.0 12.8 4.6 6.0 8.9 1.2 1 0 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase DDHD PF02862.12 CDI75868.1 - 5.4 6.7 13.6 5.5 6.7 9.4 1.1 1 0 0 1 1 1 0 DDHD domain Nucleoside_tran PF01733.13 CDI75868.1 - 5.9 5.9 5.3 6.8 5.7 3.7 1.1 1 0 0 1 1 1 0 Nucleoside transporter PAT1 PF09770.4 CDI75868.1 - 6.1 4.9 40.5 6.2 4.9 28.0 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 NlpE PF04170.7 CDI75868.1 - 6.4 7.2 13.0 10 6.5 9.0 1.5 1 1 0 1 1 1 0 NlpE N-terminal domain UPF0565 PF10561.4 CDI75868.1 - 6.9 5.4 14.2 8.3 5.2 9.9 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0565 DUF4446 PF14584.1 CDI75868.1 - 7 6.4 11.6 8.5 6.1 8.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) Activator_LAG-3 PF11498.3 CDI75872.1 - 0.0015 17.3 20.1 0.0015 17.3 13.9 10.8 10 1 1 11 11 11 4 Transcriptional activator LAG-3 Pkinase PF00069.20 CDI75874.1 - 0.042 12.9 10.8 0.083 12.0 0.0 3.9 4 1 1 5 5 5 0 Protein kinase domain Med15 PF09606.5 CDI75875.1 - 3.9e-05 22.0 93.7 3.9e-05 22.0 64.9 4.3 2 1 0 3 3 3 1 ARC105 or Med15 subunit of Mediator complex non-fungal Sporozoite_P67 PF05642.6 CDI75875.1 - 0.0012 16.8 8.8 0.0012 16.8 6.1 4.9 3 1 0 4 4 4 1 Sporozoite P67 surface antigen CAF-1_p150 PF11600.3 CDI75876.1 - 0.45 9.8 12.8 0.75 9.1 8.8 1.4 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Med15 PF09606.5 CDI75876.1 - 1.4 7.0 21.3 1.9 6.5 14.8 1.3 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal BLVR PF06375.6 CDI75878.1 - 0.00048 19.9 3.3 0.00048 19.9 2.3 3.1 3 0 0 3 3 3 1 Bovine leukaemia virus receptor (BLVR) Herpes_DNAp_acc PF04929.7 CDI75878.1 - 0.0013 17.7 1.0 0.0013 17.7 0.7 2.3 1 1 0 2 2 2 1 Herpes DNA replication accessory factor Peptidase_S49_N PF08496.5 CDI75878.1 - 0.0044 16.8 33.3 0.021 14.5 4.9 3.2 3 0 0 3 3 3 2 Peptidase family S49 N-terminal DUF2052 PF09747.4 CDI75878.1 - 0.01 15.7 46.3 0.47 10.3 8.9 3.1 3 0 0 3 3 3 0 Coiled-coil domain containing protein (DUF2052) FAM176 PF14851.1 CDI75878.1 - 0.017 14.8 27.2 0.25 11.0 3.3 3.3 3 0 0 3 3 3 0 FAM176 family BAF1_ABF1 PF04684.8 CDI75878.1 - 0.042 12.6 99.0 0.055 12.3 20.9 3.1 3 0 0 3 3 3 0 BAF1 / ABF1 chromatin reorganising factor DUF1510 PF07423.6 CDI75878.1 - 0.082 12.2 46.2 0.8 9.0 9.7 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1510) 2-Hacid_dh_C PF02826.14 CDI75878.1 - 0.11 11.6 0.1 0.11 11.6 0.1 3.3 3 1 0 3 3 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain OATP PF03137.15 CDI75878.1 - 0.17 9.8 27.3 0.076 11.0 1.8 3.1 3 0 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family Isy1 PF06246.7 CDI75878.1 - 0.19 11.1 34.1 0.42 9.9 5.2 3.0 3 0 0 3 3 3 0 Isy1-like splicing family EIIBC-GUT_N PF03612.9 CDI75878.1 - 0.19 11.3 30.0 2.1 7.9 0.6 3.2 3 0 0 3 3 3 0 Sorbitol phosphotransferase enzyme II N-terminus DUF2956 PF11169.3 CDI75878.1 - 0.23 11.4 49.8 0.58 10.1 10.2 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2956) Dala_Dala_lig_N PF01820.16 CDI75878.1 - 0.25 11.6 23.0 1.1 9.6 3.1 3.2 3 0 0 3 3 3 0 D-ala D-ala ligase N-terminus CRF1 PF10380.4 CDI75878.1 - 0.6 10.4 27.1 0.58 10.5 3.2 3.2 3 0 0 3 3 3 0 Transcription factor CRF1 DUF1266 PF06889.6 CDI75878.1 - 0.65 9.7 33.0 2.9 7.6 1.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1266) PAXIP1_C PF15364.1 CDI75878.1 - 0.83 9.5 38.4 0.6 10.0 4.0 3.4 3 0 0 3 3 3 0 PAXIP1-associated-protein-1 C term PTIP binding protein Cwf_Cwc_15 PF04889.7 CDI75878.1 - 0.93 9.1 45.3 0.022 14.4 7.5 3.1 3 0 0 3 3 3 0 Cwf15/Cwc15 cell cycle control protein Pox_Ag35 PF03286.9 CDI75878.1 - 0.94 8.9 35.5 0.25 10.8 5.4 3.1 3 0 0 3 3 3 0 Pox virus Ag35 surface protein BORG_CEP PF14957.1 CDI75878.1 - 1.2 10.0 29.1 4.6 8.1 5.2 3.2 3 0 0 3 3 3 0 Cdc42 effector F-protein PF00469.15 CDI75878.1 - 2.5 7.4 39.1 0.082 12.2 8.3 3.1 3 0 0 3 3 3 0 Negative factor, (F-Protein) or Nef Glyco_transf_15 PF01793.11 CDI75878.1 - 2.5 6.9 35.7 0.8 8.5 6.1 3.0 3 0 0 3 3 3 0 Glycolipid 2-alpha-mannosyltransferase DUF2201_N PF13203.1 CDI75878.1 - 2.7 7.0 45.3 1.6 7.8 6.6 3.0 3 0 0 3 3 3 0 Putative metallopeptidase domain DUF3449 PF11931.3 CDI75878.1 - 4.6 6.7 41.5 0.95 8.9 8.6 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF3449) DUF3807 PF12720.2 CDI75878.1 - 5 7.2 49.9 1 9.5 8.9 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3807) GOLD_2 PF13897.1 CDI75878.1 - 5.3 7.2 24.2 7.4 6.7 2.7 3.3 3 0 0 3 3 3 0 Golgi-dynamics membrane-trafficking DUF572 PF04502.8 CDI75878.1 - 6 5.9 39.7 1.7 7.7 7.7 3.0 3 0 0 3 3 3 0 Family of unknown function (DUF572) Pap_E4 PF02711.9 CDI75878.1 - 6.3 7.6 33.6 5.7 7.8 4.8 3.2 3 0 0 3 3 3 0 E4 protein Pex14_N PF04695.8 CDI75878.1 - 7.3 6.6 64.6 0.45 10.5 2.5 3.1 2 1 1 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region CDC45 PF02724.9 CDI75878.1 - 8.1 4.3 35.2 3.1 5.7 5.4 3.0 3 0 0 3 3 3 0 CDC45-like protein DUF3121 PF11319.3 CDI75878.1 - 8.6 5.8 33.2 0.57 9.6 3.6 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3121) U79_P34 PF03064.11 CDI75878.1 - 9.1 5.7 29.3 1.4 8.4 3.0 3.1 3 0 0 3 3 3 0 HSV U79 / HCMV P34 SDA1 PF05285.7 CDI75878.1 - 9.2 5.4 37.8 3.3 6.8 0.1 2.2 2 1 0 2 2 2 0 SDA1 Stig1 PF04885.8 CDI75878.1 - 9.8 6.3 20.7 3.7 7.7 4.4 3.1 3 0 0 3 3 3 0 Stigma-specific protein, Stig1 Trypan_PARP PF05887.6 CDI75879.1 - 6.9e-06 25.9 8.7 6.9e-06 25.9 6.1 4.5 2 2 2 4 4 4 1 Procyclic acidic repetitive protein (PARP) DUF1510 PF07423.6 CDI75880.1 - 2.5 7.4 24.7 2.5 7.4 17.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) SelP_N PF04592.9 CDI75880.1 - 3.8 6.8 26.6 3.8 6.8 18.4 1.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region FYDLN_acid PF09538.5 CDI75880.1 - 7.7 7.1 12.4 9.8 6.8 8.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) Zip PF02535.17 CDI75880.1 - 7.9 5.3 21.3 7.9 5.3 14.8 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter TMCO5 PF14992.1 CDI75881.1 - 0.017 14.2 5.5 0.019 14.0 3.8 1.1 1 0 0 1 1 1 0 TMCO5 family ERM PF00769.14 CDI75881.1 - 0.031 13.8 8.1 0.035 13.6 5.6 1.1 1 0 0 1 1 1 0 Ezrin/radixin/moesin family APG6 PF04111.7 CDI75881.1 - 0.045 12.7 7.6 0.051 12.6 5.2 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF2400 PF09674.5 CDI75881.1 - 0.047 13.3 0.7 0.055 13.1 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) OmpH PF03938.9 CDI75881.1 - 0.063 13.2 7.0 0.071 13.0 4.9 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF2408 PF10303.4 CDI75881.1 - 0.064 13.3 3.3 0.078 13.0 2.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) Suppressor_APC PF11414.3 CDI75881.1 - 0.065 13.0 3.5 0.093 12.5 2.4 1.3 1 0 0 1 1 1 0 Adenomatous polyposis coli tumour suppressor protein YbfN PF13982.1 CDI75881.1 - 0.071 13.2 0.3 0.25 11.5 0.0 1.9 1 1 2 3 3 3 0 YbfN-like lipoprotein Spc7 PF08317.6 CDI75881.1 - 0.072 11.7 6.7 0.091 11.4 4.6 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein GAS PF13851.1 CDI75881.1 - 0.12 11.6 9.8 0.14 11.3 6.8 1.1 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding COX16 PF14138.1 CDI75881.1 - 0.13 12.4 1.2 0.21 11.7 0.8 1.4 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein COX16 DUF4200 PF13863.1 CDI75881.1 - 0.14 12.0 11.4 0.15 12.0 7.2 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) MT PF12777.2 CDI75881.1 - 0.27 9.9 4.0 0.29 9.8 2.8 1.0 1 0 0 1 1 1 0 Microtubule-binding stalk of dynein motor DUF972 PF06156.8 CDI75881.1 - 0.3 11.4 4.5 0.37 11.1 3.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF972) DUF4220 PF13968.1 CDI75881.1 - 0.33 9.9 1.4 0.36 9.8 1.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4220) V_ATPase_I PF01496.14 CDI75881.1 - 0.35 8.6 4.1 0.37 8.5 2.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CorA PF01544.13 CDI75881.1 - 0.47 9.4 4.6 0.62 9.0 3.2 1.3 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein Syntaxin-6_N PF09177.6 CDI75881.1 - 0.58 10.6 4.5 0.87 10.0 0.9 2.1 1 1 1 2 2 2 0 Syntaxin 6, N-terminal ADIP PF11559.3 CDI75881.1 - 0.61 9.9 11.1 0.37 10.6 2.0 2.1 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DUF342 PF03961.8 CDI75881.1 - 0.72 8.1 6.9 0.77 8.1 4.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Atg14 PF10186.4 CDI75881.1 - 0.83 8.5 7.3 0.91 8.4 5.1 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 HAUS6_N PF14661.1 CDI75881.1 - 0.88 8.8 5.4 1.1 8.5 3.8 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus IncA PF04156.9 CDI75881.1 - 1.6 8.3 10.2 2.5 7.6 7.1 1.4 1 1 0 1 1 1 0 IncA protein FlxA PF14282.1 CDI75881.1 - 1.9 8.5 9.3 3.8 7.5 6.5 1.6 1 1 0 1 1 1 0 FlxA-like protein Syntaxin PF00804.20 CDI75881.1 - 1.9 8.7 8.4 1.1 9.4 4.1 1.8 1 1 1 2 2 2 0 Syntaxin DUF4337 PF14235.1 CDI75881.1 - 4.4 7.1 6.5 7.7 6.3 4.4 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4337) DUF2522 PF10747.4 CDI75883.1 - 0.18 11.8 4.0 0.46 10.5 2.7 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2522) DUF4604 PF15377.1 CDI75884.1 - 0.068 13.3 9.4 0.15 12.2 6.5 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4604) Chorein_N PF12624.2 CDI75884.1 - 0.11 12.0 1.2 0.32 10.5 0.9 1.8 1 0 0 1 1 1 0 N-terminal region of Chorein, a TM vesicle-mediated sorter DUF1469 PF07332.6 CDI75884.1 - 0.13 12.0 13.1 0.25 11.0 9.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1469) DUF4647 PF15504.1 CDI75884.1 - 0.16 10.8 16.5 0.23 10.3 11.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4647) SR-25 PF10500.4 CDI75884.1 - 0.37 10.2 11.9 0.2 11.0 0.4 3.0 3 0 0 3 3 3 0 Nuclear RNA-splicing-associated protein APC_CDC26 PF10471.4 CDI75884.1 - 0.39 11.4 42.2 0.4 11.4 5.4 3.6 3 0 0 3 3 3 0 Anaphase-promoting complex APC subunit 1 Dehydrin PF00257.14 CDI75884.1 - 1.8 8.8 17.6 4 7.7 12.2 1.5 1 1 0 1 1 1 0 Dehydrin IncA PF04156.9 CDI75885.1 - 4.2e-05 23.2 3.4 4.2e-05 23.2 2.3 2.6 3 0 0 3 3 3 1 IncA protein FA_desaturase PF00487.19 CDI75885.1 - 0.032 13.6 0.4 0.047 13.1 0.3 1.3 1 0 0 1 1 1 0 Fatty acid desaturase Draxin PF15550.1 CDI75885.1 - 0.43 10.1 25.0 1.7 8.2 8.7 2.4 2 0 0 2 2 2 0 Draxin DUF2052 PF09747.4 CDI75885.1 - 0.53 10.1 31.1 0.78 9.6 4.9 2.4 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) DUF4647 PF15504.1 CDI75885.1 - 0.76 8.5 39.9 0.2 10.5 14.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4647) CDC45 PF02724.9 CDI75885.1 - 1.3 7.0 25.9 0.62 8.0 4.2 2.1 2 0 0 2 2 2 0 CDC45-like protein DUF572 PF04502.8 CDI75885.1 - 1.6 7.8 41.6 0.65 9.1 16.2 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF572) Utp14 PF04615.8 CDI75885.1 - 1.7 6.7 42.2 1.3 7.1 15.9 2.0 2 0 0 2 2 2 0 Utp14 protein FAM60A PF15396.1 CDI75885.1 - 2.2 7.9 37.5 1 9.0 6.7 2.2 2 0 0 2 2 2 0 Protein Family FAM60A SPX PF03105.14 CDI75885.1 - 2.5 7.8 33.1 4.5 6.9 7.6 2.3 2 0 0 2 2 2 0 SPX domain Neur_chan_memb PF02932.11 CDI75885.1 - 2.5 7.9 34.8 0.7 9.7 6.0 2.1 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region DUF1510 PF07423.6 CDI75885.1 - 8.7 5.6 42.0 0.098 12.0 5.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) Ribosomal_60s PF00428.14 CDI75887.1 - 0.057 13.8 7.2 0.084 13.2 5.0 1.3 1 0 0 1 1 1 0 60s Acidic ribosomal protein ERM PF00769.14 CDI75887.1 - 0.28 10.6 19.4 0.33 10.4 13.5 1.1 1 0 0 1 1 1 0 Ezrin/radixin/moesin family SpaB_C PF14028.1 CDI75887.1 - 0.42 10.1 14.3 0.5 9.8 9.9 1.1 1 0 0 1 1 1 0 SpaB C-terminal domain Ycf1 PF05758.7 CDI75887.1 - 0.64 7.6 8.4 0.56 7.8 5.8 1.1 1 0 0 1 1 1 0 Ycf1 PAT1 PF09770.4 CDI75887.1 - 0.68 8.0 53.5 0.73 8.0 37.1 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF4175 PF13779.1 CDI75887.1 - 1.2 6.8 43.1 1.4 6.5 29.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) DUF1266 PF06889.6 CDI75887.1 - 4.5 7.0 7.9 7.1 6.4 5.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1266) FUSC PF04632.7 CDI75887.1 - 4.6 5.5 14.5 5.9 5.1 10.1 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family BRF1 PF07741.8 CDI75887.1 - 7.3 6.8 18.3 0.67 10.2 6.8 2.4 2 0 0 2 2 2 0 Brf1-like TBP-binding domain DUF572 PF04502.8 CDI75888.1 - 0.00076 18.7 37.0 0.00093 18.4 25.7 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) SSP160 PF06933.6 CDI75888.1 - 0.22 9.4 22.6 0.26 9.2 15.7 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 MIP-T3 PF10243.4 CDI75888.1 - 0.23 9.9 46.9 0.35 9.2 32.5 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Herpes_LMP2 PF07415.6 CDI75888.1 - 0.6 8.6 3.9 0.85 8.1 2.7 1.3 1 0 0 1 1 1 0 Gammaherpesvirus latent membrane protein (LMP2) protein DUF2981 PF11200.3 CDI75888.1 - 1.2 8.1 10.8 1.6 7.6 7.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) ERM PF00769.14 CDI75888.1 - 2.2 7.7 40.2 2.8 7.3 27.9 1.1 1 0 0 1 1 1 0 Ezrin/radixin/moesin family Daxx PF03344.10 CDI75888.1 - 3 6.2 43.4 3.8 5.8 30.1 1.0 1 0 0 1 1 1 0 Daxx Family Utp14 PF04615.8 CDI75888.1 - 3.3 5.7 45.9 4.1 5.4 31.8 1.0 1 0 0 1 1 1 0 Utp14 protein AIF-MLS PF14962.1 CDI75888.1 - 5.5 6.6 41.8 0.072 12.7 24.0 1.5 2 0 0 2 2 2 0 Mitochondria Localisation Sequence PAT1 PF09770.4 CDI75889.1 - 2.9 6.0 130.1 3.7 5.6 90.2 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SR-25 PF10500.4 CDI75890.1 - 7.5e-05 22.3 16.7 0.00011 21.7 11.6 1.2 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Med15 PF09606.5 CDI75890.1 - 0.0013 17.1 35.6 0.0015 16.8 24.7 1.0 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal Med3 PF11593.3 CDI75890.1 - 0.23 10.6 25.8 0.55 9.4 4.1 2.2 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal eIF_4EBP PF05456.6 CDI75890.1 - 0.28 10.8 15.0 0.15 11.7 0.8 2.1 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) Macoilin PF09726.4 CDI75890.1 - 0.32 9.2 13.7 0.36 9.0 9.5 1.0 1 0 0 1 1 1 0 Transmembrane protein DUF912 PF06024.7 CDI75890.1 - 0.34 11.0 9.5 3.2 7.8 1.8 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) PAT1 PF09770.4 CDI75890.1 - 0.35 9.0 29.3 0.41 8.8 20.3 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Hid1 PF12722.2 CDI75890.1 - 0.5 7.9 15.8 0.57 7.7 11.0 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Ant_C PF05586.6 CDI75890.1 - 0.73 10.3 3.8 1.2 9.6 0.2 2.1 2 0 0 2 2 2 0 Anthrax receptor C-terminus region U1snRNP70_N PF12220.3 CDI75890.1 - 0.87 9.9 15.2 3.2 8.1 4.4 2.1 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal PBP1_TM PF14812.1 CDI75890.1 - 1.9 8.8 9.8 5.6 7.3 0.1 2.2 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal PHD_3 PF13922.1 CDI75890.1 - 2.2 8.5 19.3 5.1 7.4 2.0 2.5 2 0 0 2 2 2 0 PHD domain of transcriptional enhancer, Asx DUF2547 PF10818.3 CDI75890.1 - 3.5 8.3 23.1 2.7 8.6 2.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2547) PH_4 PF15404.1 CDI75890.1 - 3.8 6.9 11.4 4 6.9 3.0 2.1 2 0 0 2 2 2 0 Pleckstrin homology domain FixO PF02433.10 CDI75890.1 - 3.9 6.7 10.5 6.9 5.9 6.7 1.7 1 1 1 2 2 2 0 Cytochrome C oxidase, mono-heme subunit/FixO DUF3408 PF11888.3 CDI75890.1 - 4 7.3 14.7 3.7 7.4 0.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3408) Trypan_glycop_C PF10659.4 CDI75890.1 - 4.4 7.6 14.1 3.6 7.9 4.4 2.2 2 0 0 2 2 2 0 Trypanosome variant surface glycoprotein C-terminal domain RLL PF10036.4 CDI75890.1 - 5 6.4 14.6 2 7.7 3.7 2.1 2 0 0 2 2 2 0 Putative carnitine deficiency-associated protein DUF3484 PF11983.3 CDI75890.1 - 5.8 7.8 20.7 4.1 8.3 1.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3484) Herpes_DNAp_acc PF04929.7 CDI75890.1 - 6.3 5.6 13.1 9.3 5.1 9.1 1.4 1 1 0 1 1 1 0 Herpes DNA replication accessory factor DUF3499 PF12005.3 CDI75890.1 - 7.3 6.7 7.0 7.8 6.6 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3499) FimP PF09766.4 CDI75891.1 - 0.072 12.1 23.2 0.077 12.0 16.1 1.2 1 0 0 1 1 1 0 Fms-interacting protein Topoisom_I_N PF02919.10 CDI75891.1 - 0.21 10.8 7.2 0.33 10.1 5.0 1.3 1 0 0 1 1 1 0 Eukaryotic DNA topoisomerase I, DNA binding fragment DUF4557 PF15101.1 CDI75891.1 - 0.32 10.8 25.2 0.34 10.7 17.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) FLO_LFY PF01698.11 CDI75891.1 - 0.37 9.5 17.0 0.4 9.4 11.8 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein DUF4392 PF14336.1 CDI75891.1 - 0.84 8.3 2.9 0.88 8.3 2.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4392) DUF702 PF05142.7 CDI75891.1 - 0.99 9.5 14.4 1.1 9.3 10.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF702) Pex14_N PF04695.8 CDI75891.1 - 1.2 9.2 22.2 1.4 8.9 15.4 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region TCP PF03634.8 CDI75891.1 - 1.3 9.4 17.7 1.4 9.2 12.2 1.1 1 0 0 1 1 1 0 TCP family transcription factor DUF2146 PF10220.4 CDI75891.1 - 1.7 6.5 15.5 1.8 6.4 10.7 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2146) FHIPEP PF00771.15 CDI75891.1 - 1.7 6.8 11.7 1.7 6.8 8.1 1.0 1 0 0 1 1 1 0 FHIPEP family DUF4045 PF13254.1 CDI75891.1 - 1.9 7.6 16.3 2.2 7.4 11.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) GOLD_2 PF13897.1 CDI75891.1 - 2.1 8.5 8.7 2.4 8.3 6.0 1.2 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking PIH1 PF08190.7 CDI75891.1 - 2.5 7.4 20.1 2.7 7.3 14.0 1.0 1 0 0 1 1 1 0 pre-RNA processing PIH1/Nop17 DUF913 PF06025.7 CDI75891.1 - 2.5 6.7 9.5 2.7 6.6 6.6 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Hid1 PF12722.2 CDI75891.1 - 2.5 5.6 19.2 2.8 5.5 13.3 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Ctr PF04145.10 CDI75891.1 - 2.5 8.1 8.9 3.2 7.7 6.2 1.3 1 0 0 1 1 1 0 Ctr copper transporter family FYDLN_acid PF09538.5 CDI75891.1 - 2.7 8.6 10.5 3.3 8.3 7.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) FAM60A PF15396.1 CDI75891.1 - 3.2 7.4 12.7 3.5 7.3 8.8 1.1 1 0 0 1 1 1 0 Protein Family FAM60A Peptidase_U57 PF05582.7 CDI75891.1 - 3.3 6.5 11.1 3.2 6.6 7.7 1.1 1 0 0 1 1 1 0 YabG peptidase U57 Auxin_canalis PF05703.6 CDI75891.1 - 3.4 7.4 7.5 3.6 7.3 5.2 1.0 1 0 0 1 1 1 0 Auxin canalisation DUF1510 PF07423.6 CDI75891.1 - 3.5 6.9 21.5 3.9 6.7 14.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) SAPS PF04499.10 CDI75891.1 - 3.7 6.0 14.9 4.1 5.9 10.3 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein LIM_bind PF01803.11 CDI75891.1 - 3.8 6.5 16.6 4.2 6.4 11.5 1.1 1 0 0 1 1 1 0 LIM-domain binding protein Gti1_Pac2 PF09729.4 CDI75891.1 - 3.9 7.3 12.2 4.5 7.1 8.5 1.2 1 0 0 1 1 1 0 Gti1/Pac2 family Raftlin PF15250.1 CDI75891.1 - 3.9 5.9 16.6 3.9 5.8 11.5 1.0 1 0 0 1 1 1 0 Raftlin TFIIA PF03153.8 CDI75891.1 - 3.9 7.2 28.4 4.4 7.1 19.7 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Late_protein_L2 PF00513.13 CDI75891.1 - 4.1 6.1 9.1 4.5 6.0 6.3 1.0 1 0 0 1 1 1 0 Late Protein L2 DDRGK PF09756.4 CDI75891.1 - 4.3 6.6 27.7 5.1 6.4 19.2 1.0 1 0 0 1 1 1 0 DDRGK domain Bud13 PF09736.4 CDI75891.1 - 4.4 7.5 24.6 5.4 7.2 17.0 1.1 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex PAT1 PF09770.4 CDI75891.1 - 4.8 5.3 37.1 4.8 5.2 25.7 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Suf PF05843.9 CDI75891.1 - 4.8 6.8 19.3 6.6 6.3 13.4 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Paramyxo_ncap PF00973.14 CDI75891.1 - 5.1 5.6 14.2 5.4 5.6 9.9 1.0 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Dynamin_N PF00350.18 CDI75891.1 - 5.3 6.8 10.1 7.1 6.4 7.0 1.3 1 0 0 1 1 1 0 Dynamin family HD-ZIP_N PF04618.7 CDI75891.1 - 5.4 7.5 8.4 7 7.2 5.9 1.2 1 0 0 1 1 1 0 HD-ZIP protein N terminus EIIBC-GUT_N PF03612.9 CDI75891.1 - 5.4 6.5 13.6 6 6.4 9.4 1.2 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Pal1 PF08316.6 CDI75891.1 - 5.6 7.4 8.7 6.6 7.1 6.0 1.2 1 0 0 1 1 1 0 Pal1 cell morphology protein SAGA-Tad1 PF12767.2 CDI75891.1 - 6.2 6.4 19.3 6.9 6.2 13.4 1.1 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit DUF2201_N PF13203.1 CDI75891.1 - 7 5.7 18.4 7.6 5.6 12.7 1.0 1 0 0 1 1 1 0 Putative metallopeptidase domain RR_TM4-6 PF06459.7 CDI75891.1 - 7.2 6.4 18.9 8.3 6.2 13.1 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Spore_coat_CotO PF14153.1 CDI75891.1 - 7.3 5.9 28.5 8.5 5.7 19.8 1.0 1 0 0 1 1 1 0 Spore coat protein CotO HGTP_anticodon2 PF12745.2 CDI75891.1 - 7.6 5.5 16.9 8.8 5.3 11.7 1.0 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs Serinc PF03348.10 CDI75891.1 - 7.8 5.0 15.7 8.1 5.0 10.9 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) Band_3_cyto PF07565.8 CDI75891.1 - 8.1 5.8 18.0 9.6 5.6 12.5 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain DDHD PF02862.12 CDI75891.1 - 8.1 6.1 17.2 8.8 6.0 12.0 1.1 1 0 0 1 1 1 0 DDHD domain IncA PF04156.9 CDI75891.1 - 8.3 5.9 28.3 8.2 5.9 19.6 1.1 1 0 0 1 1 1 0 IncA protein Tim54 PF11711.3 CDI75891.1 - 8.4 4.8 14.2 9.8 4.6 9.9 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 HSP70 PF00012.15 CDI75891.1 - 8.9 4.0 13.8 9.5 3.9 9.6 1.0 1 0 0 1 1 1 0 Hsp70 protein DUF4613 PF15390.1 CDI75891.1 - 9.1 4.3 12.8 10 4.1 8.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) GvpL_GvpF PF06386.6 CDI75891.1 - 9.2 5.7 17.4 9.8 5.6 12.1 1.0 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF Peptidase_S15 PF02129.13 CDI75891.1 - 9.3 5.5 12.2 9.9 5.4 8.5 1.1 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) DUF605 PF04652.11 CDI75892.1 - 0.00087 18.7 34.7 0.0011 18.5 24.1 1.1 1 0 0 1 1 1 1 Vta1 like DUF2232 PF09991.4 CDI75892.1 - 0.14 11.1 2.9 0.21 10.5 2.0 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) SR-25 PF10500.4 CDI75892.1 - 1.9 7.9 0.0 1.9 7.9 0.0 4.0 2 1 1 3 3 3 0 Nuclear RNA-splicing-associated protein Mitofilin PF09731.4 CDI75892.1 - 8.7 4.8 25.3 12 4.3 17.5 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein YqfQ PF14181.1 CDI75893.1 - 2.9 7.9 25.4 3.3 7.7 17.6 1.2 1 0 0 1 1 1 0 YqfQ-like protein DUF4407 PF14362.1 CDI75893.1 - 5.1 5.9 35.4 5.6 5.8 24.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) EGF_CA PF07645.10 CDI75894.1 - 7.9e-10 38.5 7.1 1.3e-09 37.8 5.0 1.3 1 0 0 1 1 1 1 Calcium-binding EGF domain cEGF PF12662.2 CDI75894.1 - 1.6e-05 24.4 6.5 0.0024 17.4 2.6 2.6 2 0 0 2 2 2 2 Complement Clr-like EGF-like EGF_3 PF12947.2 CDI75894.1 - 7.7e-05 22.5 7.7 7.7e-05 22.5 5.3 1.6 1 1 0 1 1 1 1 EGF domain FXa_inhibition PF14670.1 CDI75894.1 - 0.00044 20.3 7.8 0.00094 19.2 5.4 1.6 1 0 0 1 1 1 1 Coagulation Factor Xa inhibitory site EGF_MSP1_1 PF12946.2 CDI75894.1 - 0.044 13.5 1.2 0.084 12.6 0.8 1.5 1 0 0 1 1 1 0 MSP1 EGF domain 1 EGF PF00008.22 CDI75894.1 - 0.3 11.0 9.4 1.4 8.9 6.5 2.1 1 1 0 1 1 1 0 EGF-like domain Peptidase_C11 PF03415.9 CDI75895.1 - 8.7e-14 51.2 0.0 1.6e-11 43.8 0.0 2.2 2 0 0 2 2 2 2 Clostripain family GST_C_3 PF14497.1 CDI75896.1 - 0.0014 19.0 0.0 0.0094 16.4 0.0 2.5 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain CLAG PF03805.8 CDI75896.1 - 0.0043 14.4 0.0 0.76 7.0 0.0 2.2 2 0 0 2 2 2 2 Cytoadherence-linked asexual protein Exonuc_VII_L PF02601.10 CDI75897.1 - 2.9 7.0 9.2 8.8 5.4 6.3 1.7 1 1 0 1 1 1 0 Exonuclease VII, large subunit DUF663 PF04950.7 CDI75899.1 - 5.4e-69 232.4 0.0 2.3e-59 200.7 0.0 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF663) AARP2CN PF08142.7 CDI75899.1 - 7.4e-06 25.4 0.0 1.9e-05 24.0 0.0 1.7 1 0 0 1 1 1 1 AARP2CN (NUC121) domain CRAL_TRIO PF00650.15 CDI75900.1 - 2e-08 33.8 0.2 1e-07 31.6 0.1 1.9 1 1 1 2 2 2 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.1 CDI75900.1 - 0.087 12.7 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain CRAL_TRIO_N PF03765.10 CDI75900.1 - 0.11 12.6 0.1 0.24 11.5 0.1 1.6 1 0 0 1 1 1 0 CRAL/TRIO, N-terminal domain Guanylate_cyc PF00211.15 CDI75902.1 - 2.7e-50 170.2 0.0 8.9e-30 103.4 0.0 3.8 2 2 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain E1-E2_ATPase PF00122.15 CDI75902.1 - 0.0063 15.5 0.2 0.04 12.9 0.0 2.3 2 0 0 2 2 2 1 E1-E2 ATPase ABC_tran PF00005.22 CDI75907.1 - 2.3e-50 170.4 0.0 7.1e-27 94.3 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.2 CDI75907.1 - 2.3e-33 115.6 25.3 4.3e-26 91.7 3.6 2.4 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_21 PF13304.1 CDI75907.1 - 5e-17 62.7 0.1 4.1e-08 33.5 0.0 4.2 4 0 0 4 4 4 3 AAA domain AAA_29 PF13555.1 CDI75907.1 - 6e-06 25.6 1.1 0.06 12.8 0.1 3.0 3 0 0 3 3 3 2 P-loop containing region of AAA domain EF-hand_1 PF00036.27 CDI75907.1 - 2.2e-05 23.4 0.1 7.8e-05 21.6 0.0 2.1 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.1 CDI75907.1 - 2.9e-05 23.5 0.1 0.00012 21.6 0.0 2.1 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.1 CDI75907.1 - 0.00061 19.8 0.1 0.0018 18.3 0.1 1.8 1 0 0 1 1 1 1 EF-hand domain pair DUF258 PF03193.11 CDI75907.1 - 0.0008 18.6 0.1 0.047 12.8 0.1 2.5 3 0 0 3 3 2 1 Protein of unknown function, DUF258 AAA_23 PF13476.1 CDI75907.1 - 0.0013 19.0 2.1 0.079 13.2 0.1 2.4 2 0 0 2 2 2 1 AAA domain EF-hand_5 PF13202.1 CDI75907.1 - 0.0021 17.3 0.0 0.0058 15.9 0.0 1.8 1 0 0 1 1 1 1 EF hand SMC_N PF02463.14 CDI75907.1 - 0.004 16.3 0.2 11 5.2 0.1 3.7 3 1 0 3 3 3 0 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.1 CDI75907.1 - 0.005 16.7 0.0 0.95 9.4 0.0 2.8 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_25 PF13481.1 CDI75907.1 - 0.018 14.4 0.3 3.2 7.1 0.0 3.5 4 0 0 4 4 4 0 AAA domain MMR_HSR1 PF01926.18 CDI75907.1 - 0.029 14.3 0.4 1.1 9.2 0.1 3.1 3 0 0 3 3 3 0 50S ribosome-binding GTPase EF-hand_8 PF13833.1 CDI75907.1 - 0.08 12.5 0.6 6.8 6.3 0.0 3.1 3 0 0 3 3 3 0 EF-hand domain pair AAA_15 PF13175.1 CDI75907.1 - 0.13 11.3 0.0 3.9 6.4 0.0 2.7 3 0 0 3 3 3 0 AAA ATPase domain PCP_red PF08369.5 CDI75907.1 - 0.22 11.4 2.5 0.65 9.9 1.7 1.8 1 0 0 1 1 1 0 Proto-chlorophyllide reductase 57 kD subunit Zeta_toxin PF06414.7 CDI75907.1 - 0.24 10.4 0.1 0.71 8.9 0.0 1.8 2 0 0 2 2 2 0 Zeta toxin ArgK PF03308.11 CDI75907.1 - 0.6 8.8 0.6 2 7.1 0.1 2.0 2 0 0 2 2 2 0 ArgK protein AAA_10 PF12846.2 CDI75907.1 - 1.7 7.9 3.8 3.9 6.8 0.2 2.3 2 0 0 2 2 2 0 AAA-like domain DUF87 PF01935.12 CDI75907.1 - 1.9 8.2 2.7 2.9 7.6 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function DUF87 Activator_LAG-3 PF11498.3 CDI75909.1 - 0.17 10.5 41.2 0.18 10.5 28.5 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Suf PF05843.9 CDI75909.1 - 0.19 11.4 18.0 0.2 11.3 12.5 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Spore_coat_CotO PF14153.1 CDI75909.1 - 0.23 10.8 18.9 0.22 10.9 13.1 1.2 1 0 0 1 1 1 0 Spore coat protein CotO PBP_sp32 PF07222.7 CDI75909.1 - 0.34 10.0 15.1 0.37 9.9 10.5 1.1 1 0 0 1 1 1 0 Proacrosin binding protein sp32 DUF2232 PF09991.4 CDI75909.1 - 0.35 9.8 5.9 0.55 9.1 4.1 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) Bac_luciferase PF00296.15 CDI75909.1 - 0.54 9.3 19.9 0.64 9.0 13.8 1.0 1 0 0 1 1 1 0 Luciferase-like monooxygenase Baculo_PP31 PF05311.6 CDI75909.1 - 0.72 9.0 11.1 0.68 9.1 7.7 1.1 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) eIF-3_zeta PF05091.7 CDI75909.1 - 0.74 8.3 14.4 0.66 8.5 10.0 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) PAT1 PF09770.4 CDI75909.1 - 0.88 7.7 35.8 0.85 7.7 24.8 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 RbsD_FucU PF05025.8 CDI75909.1 - 1 9.6 12.0 1.5 9.1 8.3 1.4 1 1 0 1 1 1 0 RbsD / FucU transport protein family Serinc PF03348.10 CDI75909.1 - 1.1 7.9 12.0 1 8.0 8.3 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) CPSF100_C PF13299.1 CDI75909.1 - 1.8 8.7 10.7 1.8 8.7 7.4 1.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal FLO_LFY PF01698.11 CDI75909.1 - 1.8 7.3 14.0 1.9 7.2 9.7 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein Neur_chan_memb PF02932.11 CDI75909.1 - 1.9 8.3 5.8 1.8 8.4 4.0 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DDHD PF02862.12 CDI75909.1 - 2.4 7.8 12.0 2.4 7.8 8.3 1.1 1 0 0 1 1 1 0 DDHD domain AMP-binding PF00501.23 CDI75909.1 - 2.5 6.3 7.2 2.7 6.2 5.0 1.0 1 0 0 1 1 1 0 AMP-binding enzyme SID-1_RNA_chan PF13965.1 CDI75909.1 - 2.5 6.1 4.8 2.2 6.3 3.3 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Hamartin PF04388.7 CDI75909.1 - 2.8 6.4 14.4 2.9 6.4 10.0 1.0 1 0 0 1 1 1 0 Hamartin protein TraT PF05818.7 CDI75909.1 - 3.5 6.9 21.2 4.4 6.6 14.7 1.1 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein OATP PF03137.15 CDI75909.1 - 3.6 5.5 7.2 3.2 5.6 5.0 1.2 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family RR_TM4-6 PF06459.7 CDI75909.1 - 3.9 7.2 15.4 4.1 7.2 10.6 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF2215 PF10225.4 CDI75909.1 - 5.8 6.2 6.0 5.8 6.2 4.2 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) AAA_23 PF13476.1 CDI75909.1 - 6.1 7.1 15.4 6.7 6.9 10.6 1.1 1 0 0 1 1 1 0 AAA domain Shadoo PF14999.1 CDI75910.1 - 0.061 13.1 8.3 0.078 12.8 5.7 1.3 1 0 0 1 1 1 0 Shadow of prion protein, neuroprotective PLRV_ORF5 PF01690.12 CDI75912.1 - 2.3 7.2 33.8 3.3 6.7 23.4 1.2 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Vfa1 PF08432.5 CDI75912.1 - 6.4 6.7 32.1 3.5 7.6 2.0 2.2 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 FAM60A PF15396.1 CDI75912.1 - 6.7 6.3 32.3 5.2 6.7 12.7 2.2 2 0 0 2 2 2 0 Protein Family FAM60A MRP-S31 PF15433.1 CDI75913.1 - 0.0013 18.1 21.7 0.0017 17.8 15.0 1.1 1 0 0 1 1 1 1 Mitochondrial 28S ribosomal protein S31 Rxt3 PF08642.5 CDI75913.1 - 0.0092 16.2 5.0 0.037 14.2 0.8 2.2 2 0 0 2 2 2 1 Histone deacetylation protein Rxt3 SGT1 PF07093.6 CDI75913.1 - 0.0093 14.3 16.3 0.012 13.9 11.3 1.1 1 0 0 1 1 1 1 SGT1 protein AAA_23 PF13476.1 CDI75913.1 - 0.0096 16.2 19.1 0.016 15.5 0.2 2.1 2 0 0 2 2 2 1 AAA domain Utp12 PF04003.7 CDI75913.1 - 1.4 8.8 11.3 1.7 8.5 7.2 1.6 1 1 0 1 1 1 0 Dip2/Utp12 Family Ribonuclease_3 PF00636.21 CDI75913.1 - 2.6 8.5 6.6 7.8 6.9 4.6 1.9 1 1 0 1 1 1 0 Ribonuclease III domain Transglut_core3 PF13471.1 CDI75913.1 - 2.9 7.7 6.0 1 9.1 0.2 2.4 2 1 1 3 3 3 0 Transglutaminase-like superfamily Hid1 PF12722.2 CDI75913.1 - 8.1 3.9 16.3 11 3.5 11.3 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein PAT1 PF09770.4 CDI75913.1 - 8.2 4.5 41.5 10 4.1 28.8 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Presenilin PF01080.12 CDI75913.1 - 9.9 4.8 9.6 14 4.3 6.7 1.3 1 0 0 1 1 1 0 Presenilin Amastin PF07344.6 CDI75914.1 - 0.087 12.4 3.0 0.16 11.5 2.1 1.5 1 0 0 1 1 1 0 Amastin surface glycoprotein DUF2721 PF11026.3 CDI75914.1 - 0.099 12.2 9.2 0.018 14.6 2.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) Macoilin PF09726.4 CDI75914.1 - 4.4 5.4 7.3 5.2 5.2 5.1 1.1 1 0 0 1 1 1 0 Transmembrane protein Med15 PF09606.5 CDI75915.1 - 0.00074 17.8 29.2 0.065 11.4 0.5 2.2 2 0 0 2 2 2 2 ARC105 or Med15 subunit of Mediator complex non-fungal E_Pc_C PF06752.7 CDI75915.1 - 0.0063 16.0 19.6 0.0063 16.0 13.6 2.2 2 0 0 2 2 2 1 Enhancer of Polycomb C-terminus Folliculin PF11704.3 CDI75915.1 - 0.14 11.7 7.0 0.19 11.2 1.4 2.6 2 0 0 2 2 2 0 Vesicle coat protein involved in Golgi to plasma membrane transport AAA_23 PF13476.1 CDI75915.1 - 2.8 8.2 14.4 0.12 12.6 3.8 2.3 2 0 0 2 2 2 0 AAA domain DUF2910 PF11139.3 CDI75915.1 - 6.7 5.7 21.7 0.21 10.7 9.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2910) Tmemb_9 PF05434.6 CDI75915.1 - 8.2 6.1 9.7 4 7.1 3.2 2.5 2 0 0 2 2 2 0 TMEM9 DUF2894 PF11445.3 CDI75917.1 - 0.049 13.8 2.2 0.065 13.4 1.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2894) CTP_transf_1 PF01148.15 CDI75917.1 - 0.069 12.8 1.8 0.092 12.3 1.3 1.1 1 0 0 1 1 1 0 Cytidylyltransferase family Ribosomal_60s PF00428.14 CDI75917.1 - 0.21 12.0 5.5 0.34 11.3 3.8 1.3 1 0 0 1 1 1 0 60s Acidic ribosomal protein Mmp37 PF09139.6 CDI75918.1 - 2e-18 66.4 0.0 5.5e-17 61.7 0.0 2.5 1 1 0 1 1 1 1 Mitochondrial matrix Mmp37 SR-25 PF10500.4 CDI75919.1 - 0.00018 21.0 19.5 0.00018 21.0 13.5 2.0 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein MIP-T3 PF10243.4 CDI75919.1 - 2.9 6.2 20.6 5.2 5.4 14.3 1.4 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 SOBP PF15279.1 CDI75919.1 - 4.2 7.6 14.2 5.3 7.3 0.6 2.1 2 0 0 2 2 2 0 Sine oculis-binding protein rve PF00665.21 CDI75920.1 - 9.5e-12 45.0 0.0 1e-10 41.7 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain Chromo PF00385.19 CDI75920.1 - 5.9e-11 41.8 0.1 1.2e-10 40.8 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain RskA PF10099.4 CDI75923.1 - 0.64 9.7 24.8 1.2 8.8 8.7 2.3 2 0 0 2 2 2 0 Anti-sigma-K factor rskA Glyco_transf_34 PF05637.7 CDI75923.1 - 0.74 9.2 9.5 0.93 8.9 6.6 1.1 1 0 0 1 1 1 0 galactosyl transferase GMA12/MNN10 family Med15 PF09606.5 CDI75923.1 - 1.3 7.1 64.8 1.5 6.8 44.9 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Neur_chan_memb PF02932.11 CDI75923.1 - 9.1 6.0 13.3 12 5.6 9.2 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region SR-25 PF10500.4 CDI75925.1 - 0.0075 15.7 18.2 0.0075 15.7 12.6 7.5 3 3 4 7 7 7 2 Nuclear RNA-splicing-associated protein DNA_topoisoIV PF00521.15 CDI75926.1 - 1.1e-89 301.2 0.0 2.5e-89 300.0 0.0 1.5 1 1 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A DNA_gyraseB PF00204.20 CDI75926.1 - 3.4e-28 98.0 0.4 7.9e-28 96.8 0.2 1.5 1 0 0 1 1 1 1 DNA gyrase B Toprim PF01751.17 CDI75926.1 - 5.5e-14 51.9 0.1 3.8e-13 49.2 0.0 2.2 2 0 0 2 2 2 1 Toprim domain Draxin PF15550.1 CDI75927.1 - 0.0068 16.1 24.9 0.0085 15.7 17.2 1.2 1 0 0 1 1 1 1 Draxin MIP-T3 PF10243.4 CDI75927.1 - 1.1 7.6 46.2 1.5 7.2 32.0 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Macoilin PF09726.4 CDI75927.1 - 2 6.5 53.2 2.6 6.2 36.9 1.1 1 0 0 1 1 1 0 Transmembrane protein DUF936 PF06075.7 CDI75927.1 - 6.9 5.4 32.6 7.5 5.3 22.6 1.2 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) EphA2_TM PF14575.1 CDI75928.1 - 0.12 12.8 5.9 0.41 11.0 0.4 2.4 1 1 1 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain SDF PF00375.13 CDI75928.1 - 0.54 8.9 12.6 0.58 8.8 0.9 2.0 1 1 1 2 2 2 0 Sodium:dicarboxylate symporter family DUF4179 PF13786.1 CDI75928.1 - 0.8 9.9 14.2 0.27 11.4 1.8 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4179) CD20 PF04103.10 CDI75928.1 - 0.82 9.5 9.2 0.85 9.5 3.6 2.1 1 1 1 2 2 2 0 CD20-like family Semialdhyde_dhC PF02774.13 CDI75928.1 - 1.1 9.1 12.9 1.2 8.9 8.9 1.0 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, dimerisation domain RAB3GAP2_N PF14655.1 CDI75928.1 - 1.6 7.6 21.0 0.46 9.4 3.8 2.0 1 1 1 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus RskA PF10099.4 CDI75928.1 - 3.3 7.4 40.6 11 5.6 13.8 2.5 1 1 1 2 2 2 0 Anti-sigma-K factor rskA Claudin_2 PF13903.1 CDI75928.1 - 3.4 7.3 22.2 0.7 9.5 4.6 2.3 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction DUF2967 PF11179.3 CDI75928.1 - 3.9 6.8 31.2 0.98 8.8 11.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2967) FAM60A PF15396.1 CDI75928.1 - 7 6.3 10.3 9.4 5.9 7.2 1.4 1 0 0 1 1 1 0 Protein Family FAM60A Tmemb_9 PF05434.6 CDI75928.1 - 8.6 6.0 11.0 6.9 6.4 1.0 2.3 2 0 0 2 2 2 0 TMEM9 Otopetrin PF03189.8 CDI75928.1 - 9 5.1 9.2 11 4.8 6.4 1.2 1 0 0 1 1 1 0 Otopetrin CAF-1_p150 PF11600.3 CDI75929.1 - 0.014 14.7 18.1 0.016 14.5 12.6 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Asp-B-Hydro_N PF05279.6 CDI75929.1 - 0.31 10.8 16.7 0.34 10.7 11.5 1.0 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region FLO_LFY PF01698.11 CDI75929.1 - 1.3 7.8 12.5 1.3 7.7 8.6 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein AAA_23 PF13476.1 CDI75929.1 - 1.6 9.0 16.2 1.9 8.7 11.2 1.2 1 0 0 1 1 1 0 AAA domain BTV_NS2 PF04514.7 CDI75929.1 - 3.5 6.4 12.3 3.5 6.4 8.5 1.0 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 HemX PF04375.9 CDI75929.1 - 5.1 5.5 31.3 5.9 5.3 21.7 1.0 1 0 0 1 1 1 0 HemX DUF2407_C PF13373.1 CDI75929.1 - 6.2 6.7 10.4 6.7 6.6 7.2 1.2 1 0 0 1 1 1 0 DUF2407 C-terminal domain MFS_1 PF07690.11 CDI75931.1 - 3.2e-21 75.4 0.7 1e-14 54.0 0.0 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 CDI75931.1 - 1.4e-07 30.2 0.1 3.4e-07 29.0 0.0 1.5 1 1 0 1 1 1 1 MFS/sugar transport protein OATP PF03137.15 CDI75931.1 - 1.7e-07 29.7 0.3 3e-06 25.5 0.0 2.1 2 0 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family ATG22 PF11700.3 CDI75931.1 - 3.2e-06 25.9 0.0 0.0035 15.8 0.0 2.3 2 0 0 2 2 2 2 Vacuole effluxer Atg22 like Sugar_tr PF00083.19 CDI75931.1 - 4.3e-05 22.2 8.9 0.00054 18.6 6.2 2.9 1 1 0 1 1 1 1 Sugar (and other) transporter IncA PF04156.9 CDI75931.1 - 5.1e-05 22.9 13.4 0.019 14.5 1.5 3.1 2 0 0 2 2 2 2 IncA protein DUF533 PF04391.7 CDI75931.1 - 0.0053 16.1 4.8 0.0053 16.1 3.3 3.3 3 0 0 3 3 3 1 Protein of unknown function (DUF533) DUF4199 PF13858.1 CDI75931.1 - 0.027 14.3 1.5 2.8 7.8 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4199) zf-DHHC PF01529.15 CDI75931.1 - 0.11 11.9 0.0 5.6 6.3 0.0 2.3 2 0 0 2 2 2 0 DHHC palmitoyltransferase FHIPEP PF00771.15 CDI75931.1 - 0.17 10.2 2.7 3.5 5.8 0.2 2.1 2 0 0 2 2 2 0 FHIPEP family FPN1 PF06963.7 CDI75931.1 - 0.25 9.6 2.7 3.6 5.8 0.7 2.5 2 1 0 2 2 2 0 Ferroportin1 (FPN1) EphA2_TM PF14575.1 CDI75931.1 - 0.7 10.3 3.0 4.3 7.8 0.2 2.7 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Spt20 PF12090.3 CDI75931.1 - 0.86 8.9 14.0 2.7 7.3 4.4 2.5 3 0 0 3 3 3 0 Spt20 family G0-G1_switch_2 PF15103.1 CDI75931.1 - 6 7.1 13.6 3.3 7.9 0.2 3.2 3 0 0 3 3 3 0 G0/G1 switch protein 2 FAM176 PF14851.1 CDI75931.1 - 6.6 6.3 15.5 0.05 13.2 0.7 3.0 3 0 0 3 3 3 0 FAM176 family Kinesin PF00225.18 CDI75932.1 - 7.8e-05 21.5 0.7 3.2 6.3 0.0 4.6 4 1 0 4 4 4 3 Kinesin motor domain DUF1003 PF06210.6 CDI75933.1 - 0.059 13.2 0.1 0.11 12.4 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1003) DUF1777 PF08648.7 CDI75934.1 - 0.22 11.2 141.5 4.3 7.0 41.9 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF1777) MIP-T3 PF10243.4 CDI75934.1 - 2.8 6.3 102.1 3.7 5.8 70.8 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 CAF-1_p150 PF11600.3 CDI75935.1 - 2.4 7.5 55.5 3.2 7.0 38.4 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Peptidase_S49_N PF08496.5 CDI75936.1 - 1.1 8.9 29.8 0.13 12.0 8.5 2.1 2 0 0 2 2 2 0 Peptidase family S49 N-terminal SAPS PF04499.10 CDI75936.1 - 1.4 7.4 21.6 1.8 7.0 15.0 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF3123 PF11321.3 CDI75936.1 - 1.6 9.0 28.3 0.17 12.1 6.6 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3123) Pap_E4 PF02711.9 CDI75936.1 - 4 8.3 25.8 8.2 7.3 5.8 2.4 2 0 0 2 2 2 0 E4 protein AAA_23 PF13476.1 CDI75936.1 - 6.3 7.0 30.1 3.7 7.8 7.6 2.1 2 0 0 2 2 2 0 AAA domain Peptidase_U57 PF05582.7 CDI75936.1 - 9 5.1 24.7 3.4 6.5 8.6 2.1 2 0 0 2 2 2 0 YabG peptidase U57 DIPSY PF11763.3 CDI75938.1 - 0.05 13.3 0.0 0.077 12.7 0.0 1.3 1 1 0 1 1 1 0 Cell-wall adhesin ligand-binding C-terminal WD40 PF00400.27 CDI75939.1 - 8.2e-16 57.2 5.1 2.1e-05 24.1 0.0 4.1 4 0 0 4 4 4 3 WD domain, G-beta repeat AAA_23 PF13476.1 CDI75939.1 - 0.23 11.7 5.6 0.037 14.3 0.6 2.0 2 1 0 2 2 2 0 AAA domain DUF3035 PF11233.3 CDI75941.1 - 0.67 9.9 9.3 0.087 12.8 3.4 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3035) DUF4557 PF15101.1 CDI75942.1 - 0.016 15.0 26.1 0.017 15.0 18.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) Paf1 PF03985.8 CDI75942.1 - 0.052 12.2 15.8 0.052 12.2 10.9 1.0 1 0 0 1 1 1 0 Paf1 Sugar_tr PF00083.19 CDI75942.1 - 0.055 12.0 1.8 0.059 11.9 1.3 1.0 1 0 0 1 1 1 0 Sugar (and other) transporter FimP PF09766.4 CDI75942.1 - 0.077 12.0 25.4 0.083 11.9 17.6 1.2 1 0 0 1 1 1 0 Fms-interacting protein Polyoma_lg_T_C PF06431.6 CDI75942.1 - 0.21 10.2 5.9 0.22 10.1 4.1 1.0 1 0 0 1 1 1 0 Polyomavirus large T antigen C-terminus DDHD PF02862.12 CDI75942.1 - 0.22 11.2 13.3 0.23 11.2 9.2 1.0 1 0 0 1 1 1 0 DDHD domain CPSF100_C PF13299.1 CDI75942.1 - 0.26 11.4 12.0 0.27 11.4 8.3 1.1 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Band_3_cyto PF07565.8 CDI75942.1 - 0.62 9.5 16.9 0.62 9.5 11.7 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain PP_kinase_N PF13089.1 CDI75942.1 - 0.63 10.1 11.5 0.81 9.8 8.0 1.3 1 0 0 1 1 1 0 Polyphosphate kinase N-terminal domain Otopetrin PF03189.8 CDI75942.1 - 0.65 8.9 5.8 0.62 8.9 4.0 1.0 1 0 0 1 1 1 0 Otopetrin KfrA_N PF11740.3 CDI75942.1 - 1.2 9.5 28.4 1.4 9.3 19.7 1.1 1 0 0 1 1 1 0 Plasmid replication region DNA-binding N-term Hid1 PF12722.2 CDI75942.1 - 1.7 6.2 15.5 1.7 6.2 10.8 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein AUX_IAA PF02309.11 CDI75942.1 - 1.8 8.2 15.8 1.9 8.1 10.9 1.1 1 0 0 1 1 1 0 AUX/IAA family Baculo_PP31 PF05311.6 CDI75942.1 - 2.3 7.4 18.5 2.4 7.3 12.8 1.0 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) Na_trans_assoc PF06512.8 CDI75942.1 - 2.3 8.1 13.7 3 7.7 9.5 1.2 1 0 0 1 1 1 0 Sodium ion transport-associated DUF3987 PF13148.1 CDI75942.1 - 2.7 6.4 14.2 3 6.3 9.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) FAM60A PF15396.1 CDI75942.1 - 4.2 7.0 12.9 4.4 7.0 8.9 1.1 1 0 0 1 1 1 0 Protein Family FAM60A Het-C PF07217.6 CDI75942.1 - 4.2 5.4 12.4 3.8 5.5 8.6 1.0 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C UPF0052 PF01933.13 CDI75942.1 - 4.8 6.4 6.7 5.1 6.3 4.6 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0052 Cellulose_synt PF03552.9 CDI75942.1 - 5.1 5.2 6.9 4.7 5.3 4.8 1.0 1 0 0 1 1 1 0 Cellulose synthase Zip PF02535.17 CDI75942.1 - 5.5 5.9 8.9 5.5 5.8 6.2 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter DUF3276 PF11680.3 CDI75942.1 - 6 6.6 12.0 7.7 6.3 8.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3276) PAT1 PF09770.4 CDI75942.1 - 7 4.7 41.7 7.1 4.7 28.9 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 AAA_23 PF13476.1 CDI75942.1 - 7 6.9 21.6 7.5 6.8 15.0 1.1 1 0 0 1 1 1 0 AAA domain FLO_LFY PF01698.11 CDI75942.1 - 7.2 5.3 16.8 7.2 5.3 11.6 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein AIF_C PF14721.1 CDI75942.1 - 7.3 6.8 17.0 9.3 6.5 11.8 1.1 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term EIIBC-GUT_N PF03612.9 CDI75942.1 - 8.1 6.0 13.4 8.6 5.9 9.3 1.1 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus DUF4220 PF13968.1 CDI75942.1 - 8.1 5.4 8.4 7.9 5.4 5.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4220) SprA-related PF12118.3 CDI75942.1 - 8.4 5.6 40.7 8.5 5.6 28.2 1.0 1 0 0 1 1 1 0 SprA-related family DUF4512 PF14975.1 CDI75942.1 - 9.1 7.1 10.3 12 6.8 7.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4512) Pal1 PF08316.6 CDI75942.1 - 9.5 6.6 9.4 10 6.5 6.5 1.1 1 0 0 1 1 1 0 Pal1 cell morphology protein AAA_23 PF13476.1 CDI75943.1 - 0.0017 18.7 7.9 0.0022 18.3 5.5 1.1 1 0 0 1 1 1 1 AAA domain FAM196 PF15265.1 CDI75943.1 - 0.96 8.6 39.6 1.2 8.3 27.4 1.1 1 0 0 1 1 1 0 FAM196 family Rep_4 PF05797.6 CDI75943.1 - 7.2 5.2 13.2 11 4.5 9.1 1.4 1 1 0 1 1 1 0 Yeast trans-acting factor (REP1/REP2) Pox_E2-like PF04497.7 CDI75944.1 - 0.47 8.4 6.8 0.59 8.0 4.7 1.0 1 0 0 1 1 1 0 Poxviridae protein RAP1 PF07218.6 CDI75944.1 - 3.8 5.4 18.8 4.7 5.1 13.0 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) RTC_insert PF05189.8 CDI75945.1 - 1.5e-06 28.1 19.1 5.4e-06 26.3 0.1 3.6 3 1 1 4 4 4 2 RNA 3'-terminal phosphate cyclase (RTC), insert domain TerB-C PF15615.1 CDI75945.1 - 0.22 11.7 6.5 4.4 7.5 0.2 2.9 3 0 0 3 3 3 0 TerB-C domain Trypan_PARP PF05887.6 CDI75946.1 - 0.0033 17.2 20.1 0.0038 17.0 13.9 1.0 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) zf-C4H2 PF10146.4 CDI75946.1 - 0.025 14.6 5.9 0.032 14.2 4.1 1.1 1 0 0 1 1 1 0 Zinc finger-containing protein Nop14 PF04147.7 CDI75946.1 - 0.046 11.6 7.6 0.045 11.6 5.2 1.0 1 0 0 1 1 1 0 Nop14-like family NAM-associated PF14303.1 CDI75946.1 - 0.14 12.5 9.0 0.14 12.4 6.2 1.1 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain SMN PF06003.7 CDI75946.1 - 0.17 10.9 4.2 0.22 10.6 2.9 1.1 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) CDC45 PF02724.9 CDI75946.1 - 0.18 9.7 8.2 0.16 9.9 5.7 1.0 1 0 0 1 1 1 0 CDC45-like protein CAP_N PF01213.14 CDI75946.1 - 0.64 9.2 6.4 0.8 8.9 4.5 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Ebola_NP PF05505.7 CDI75946.1 - 1.1 7.1 6.3 1.3 7.0 4.4 1.0 1 0 0 1 1 1 0 Ebola nucleoprotein DUF4551 PF15087.1 CDI75946.1 - 1.5 7.1 4.9 1.5 7.0 3.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) SAPS PF04499.10 CDI75946.1 - 1.8 7.1 5.3 1.7 7.1 3.7 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Shadoo PF14999.1 CDI75946.1 - 2 8.2 15.5 3.1 7.6 10.7 1.3 1 0 0 1 1 1 0 Shadow of prion protein, neuroprotective VID27 PF08553.5 CDI75946.1 - 2.7 6.1 5.2 2.4 6.2 3.6 1.0 1 0 0 1 1 1 0 VID27 cytoplasmic protein Cytomega_UL84 PF06284.6 CDI75946.1 - 3.3 6.0 5.8 3.5 5.9 4.0 1.1 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein MCPVI PF02993.9 CDI75946.1 - 9.7 6.2 8.4 13 5.8 5.8 1.2 1 0 0 1 1 1 0 Minor capsid protein VI SAGA-Tad1 PF12767.2 CDI75947.1 - 0.0016 18.1 27.2 0.0019 17.9 18.9 1.0 1 0 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit Cwf_Cwc_15 PF04889.7 CDI75947.1 - 0.19 11.3 20.6 0.32 10.6 14.3 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Vfa1 PF08432.5 CDI75947.1 - 0.46 10.4 26.0 0.62 10.0 18.0 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Plasmodium_Vir PF05795.6 CDI75947.1 - 0.48 9.5 7.2 0.67 9.0 5.0 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein DUF4647 PF15504.1 CDI75947.1 - 0.52 9.1 30.2 0.67 8.7 20.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4647) AvrE PF11725.3 CDI75947.1 - 2.3 5.1 27.5 2.5 5.0 19.1 1.0 1 0 0 1 1 1 0 Pathogenicity factor APC_CDC26 PF10471.4 CDI75948.1 - 0.011 16.4 4.4 0.011 16.4 3.0 4.6 2 1 0 2 2 2 0 Anaphase-promoting complex APC subunit 1 PAT1 PF09770.4 CDI75948.1 - 0.74 7.9 74.9 0.044 12.0 41.6 2.1 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 SAGA-Tad1 PF12767.2 CDI75948.1 - 0.9 9.1 29.2 1.5 8.4 17.1 2.2 2 0 0 2 2 2 0 Transcriptional regulator of RNA polII, SAGA, subunit Band_3_cyto PF07565.8 CDI75948.1 - 4.4 6.7 29.2 21 4.4 17.9 2.3 2 0 0 2 2 2 0 Band 3 cytoplasmic domain Rhodanese PF00581.15 CDI75949.1 - 3.2e-15 56.4 0.3 0.00019 21.7 0.0 3.3 3 0 0 3 3 3 3 Rhodanese-like domain Med15 PF09606.5 CDI75949.1 - 3.7e-06 25.4 6.0 3.7e-06 25.4 4.2 2.6 2 1 0 2 2 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal Secretin_N_2 PF07655.8 CDI75949.1 - 0.0022 18.3 5.9 0.0022 18.3 4.1 3.9 3 1 0 3 3 2 1 Secretin N-terminal domain DUF2722 PF10846.3 CDI75949.1 - 0.0047 16.0 0.4 0.0047 16.0 0.3 3.8 2 1 1 3 3 2 1 Protein of unknown function (DUF2722) Ribosomal_60s PF00428.14 CDI75949.1 - 0.033 14.5 1.5 0.033 14.5 1.1 2.6 3 0 0 3 3 2 0 60s Acidic ribosomal protein Serinc PF03348.10 CDI75949.1 - 0.062 12.0 4.8 0.96 8.0 0.4 2.6 2 0 0 2 2 2 0 Serine incorporator (Serinc) Spt20 PF12090.3 CDI75949.1 - 0.17 11.2 20.7 0.11 11.8 0.9 3.3 4 0 0 4 4 4 0 Spt20 family Mus7 PF09462.5 CDI75949.1 - 0.27 10.0 11.3 0.43 9.3 1.4 2.2 2 0 0 2 2 2 0 Mus7/MMS22 family CemA PF03040.9 CDI75949.1 - 0.41 10.2 2.2 1.5 8.3 0.2 2.1 2 0 0 2 2 2 0 CemA family Glt_symporter PF03616.9 CDI75949.1 - 0.58 8.5 2.0 2.9 6.2 0.2 2.1 2 0 0 2 2 2 0 Sodium/glutamate symporter 7tm_1 PF00001.16 CDI75949.1 - 0.59 9.2 3.0 8.3 5.4 0.0 2.5 2 0 0 2 2 2 0 7 transmembrane receptor (rhodopsin family) AAA_11 PF13086.1 CDI75949.1 - 0.91 9.0 13.0 1.9 8.0 0.6 2.7 2 1 0 2 2 2 0 AAA domain FHIPEP PF00771.15 CDI75949.1 - 0.99 7.6 7.7 6.3 5.0 0.1 2.3 2 0 0 2 2 2 0 FHIPEP family NPH3 PF03000.9 CDI75949.1 - 1.1 8.6 9.3 0.31 10.5 0.3 2.6 3 0 0 3 3 3 0 NPH3 family DUF808 PF05661.7 CDI75949.1 - 2.4 6.8 5.5 2.4 6.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF808) Ctr PF04145.10 CDI75949.1 - 3 7.8 11.6 2.7 8.0 0.1 3.6 3 1 0 3 3 3 0 Ctr copper transporter family GDE_N PF12439.3 CDI75949.1 - 6.6 5.8 8.8 2.5 7.2 0.7 2.2 2 0 0 2 2 2 0 Glycogen debranching enzyme N terminal RAB3GAP2_N PF14655.1 CDI75949.1 - 8 5.3 23.5 0.28 10.1 2.3 2.7 3 0 0 3 3 3 0 Rab3 GTPase-activating protein regulatory subunit N-terminus IncA PF04156.9 CDI75951.1 - 0.22 11.1 18.5 0.38 10.3 12.9 1.4 1 0 0 1 1 1 0 IncA protein GPCR_chapero_1 PF11904.3 CDI75951.1 - 0.38 9.8 16.6 0.098 11.7 8.5 1.9 2 0 0 2 2 2 0 GPCR-chaperone Tetraspannin PF00335.15 CDI75951.1 - 3 7.0 12.7 3.7 6.7 7.5 1.9 2 0 0 2 2 2 0 Tetraspanin family DUF4557 PF15101.1 CDI75951.1 - 3.1 7.5 21.7 0.13 12.0 11.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4557) Peptidase_S49_N PF08496.5 CDI75951.1 - 3.9 7.2 14.5 6.3 6.5 10.0 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal CAF-1_p150 PF11600.3 CDI75951.1 - 4.2 6.6 28.2 3.4 6.9 9.2 2.2 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF2347 PF09804.4 CDI75951.1 - 5.5 6.1 13.4 0.12 11.6 4.6 1.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2347) CoA_binding PF02629.14 CDI75952.1 - 2.5e-25 88.8 0.0 8.5e-25 87.0 0.0 1.9 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.14 CDI75952.1 - 4.6e-11 42.5 0.7 2.4e-09 36.9 0.1 2.2 1 1 1 2 2 2 2 CoA-ligase SseB PF07179.7 CDI75952.1 - 0.026 14.3 0.0 0.048 13.4 0.0 1.3 1 0 0 1 1 1 0 SseB protein N-terminal domain DUF384 PF04064.8 CDI75953.1 - 2.3e-11 43.0 0.0 5.4e-11 41.8 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF384) FimP PF09766.4 CDI75953.1 - 0.86 8.6 22.9 0.69 8.9 6.7 3.2 3 0 0 3 3 3 0 Fms-interacting protein DUF912 PF06024.7 CDI75953.1 - 2 8.4 9.1 25 5.0 3.0 3.1 3 0 0 3 3 3 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DDHD PF02862.12 CDI75953.1 - 3.1 7.5 7.7 1.9 8.2 3.5 1.9 2 0 0 2 2 2 0 DDHD domain Pex14_N PF04695.8 CDI75953.1 - 3.8 7.5 16.0 2.8 7.9 2.4 3.3 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF2828 PF11443.3 CDI75953.1 - 4.4 5.4 8.4 8.8 4.3 5.8 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF2828) Peptidase_C14 PF00656.17 CDI75954.1 - 3.7e-29 102.1 0.0 3.7e-29 102.1 0.0 3.2 3 1 0 3 3 3 1 Caspase domain Cpn60_TCP1 PF00118.19 CDI75957.1 - 3.8e-20 71.9 0.0 4.4e-20 71.7 0.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family SprA-related PF12118.3 CDI75958.1 - 0.00085 18.7 37.1 0.00085 18.7 25.7 14.3 4 2 4 8 8 8 2 SprA-related family BAF1_ABF1 PF04684.8 CDI75958.1 - 0.0017 17.3 16.3 0.0017 17.3 11.3 21.9 8 7 11 21 21 21 1 BAF1 / ABF1 chromatin reorganising factor Herpes_UL87 PF03043.9 CDI75958.1 - 0.013 13.9 0.0 0.013 13.9 0.0 6.7 3 2 4 7 7 7 0 Herpesvirus UL87 family TauE PF01925.14 CDI75959.1 - 0.38 10.1 19.1 0.042 13.2 7.2 2.4 2 0 0 2 2 2 0 Sulfite exporter TauE/SafE UBA PF00627.26 CDI75960.1 - 1.3e-07 31.2 0.2 4.1e-07 29.6 0.2 1.9 1 0 0 1 1 1 1 UBA/TS-N domain PUB PF09409.5 CDI75960.1 - 8.9e-05 22.1 0.0 0.001 18.7 0.0 2.3 2 0 0 2 2 2 1 PUB domain Med15 PF09606.5 CDI75960.1 - 0.042 12.0 31.3 0.056 11.6 21.7 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF16 PF01519.11 CDI75960.1 - 0.05 13.8 6.2 0.081 13.1 4.3 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF16 DUF1863 PF08937.6 CDI75960.1 - 0.3 11.1 1.8 6.6 6.7 0.0 2.3 2 0 0 2 2 2 0 MTH538 TIR-like domain (DUF1863) TFIIA PF03153.8 CDI75960.1 - 8.4 6.1 28.2 14 5.4 19.5 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PAT1 PF09770.4 CDI75960.1 - 8.8 4.4 25.3 11 4.0 17.6 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Ribosomal_60s PF00428.14 CDI75961.1 - 0.0089 16.4 5.4 0.0089 16.4 3.7 5.4 3 2 1 4 4 4 1 60s Acidic ribosomal protein LMBR1 PF04791.11 CDI75961.1 - 0.47 8.9 1.9 1 7.8 1.3 1.6 1 0 0 1 1 1 0 LMBR1-like membrane protein FimP PF09766.4 CDI75961.1 - 1.7 7.6 34.9 6.6 5.6 16.9 3.4 3 0 0 3 3 3 0 Fms-interacting protein DUF4220 PF13968.1 CDI75961.1 - 4.3 6.3 11.6 0.87 8.6 4.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4220) 5_nucleotid PF05761.9 CDI75961.1 - 6.5 5.1 11.0 15 3.9 7.6 1.6 1 0 0 1 1 1 0 5' nucleotidase family DUF4557 PF15101.1 CDI75962.1 - 0.0018 18.1 25.0 0.002 18.0 17.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4557) Rtf2 PF04641.7 CDI75962.1 - 0.002 17.3 10.9 0.002 17.3 7.5 1.1 1 0 0 1 1 1 1 Rtf2 RING-finger UPF0560 PF10577.4 CDI75962.1 - 0.0035 15.6 25.1 0.0037 15.6 17.4 1.0 1 0 0 1 1 1 1 Uncharacterised protein family UPF0560 FLO_LFY PF01698.11 CDI75962.1 - 0.018 13.9 12.2 0.017 13.9 8.4 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein Raftlin PF15250.1 CDI75962.1 - 0.035 12.6 12.5 0.034 12.6 8.7 1.1 1 0 0 1 1 1 0 Raftlin Band_3_cyto PF07565.8 CDI75962.1 - 0.039 13.4 14.8 0.046 13.2 10.2 1.3 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Pex14_N PF04695.8 CDI75962.1 - 0.04 13.9 27.4 0.061 13.3 19.0 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF2201_N PF13203.1 CDI75962.1 - 0.043 12.9 17.3 0.048 12.8 12.0 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain HGTP_anticodon2 PF12745.2 CDI75962.1 - 0.056 12.5 11.1 0.064 12.4 7.7 1.2 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs Hid1 PF12722.2 CDI75962.1 - 0.061 11.0 19.5 0.07 10.8 13.5 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein PAT1 PF09770.4 CDI75962.1 - 0.062 11.5 49.0 0.06 11.5 33.9 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Pox_Ag35 PF03286.9 CDI75962.1 - 0.063 12.8 11.2 0.069 12.6 7.8 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein GAGA_bind PF06217.7 CDI75962.1 - 0.072 13.0 14.1 0.07 13.0 9.8 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family DDHD PF02862.12 CDI75962.1 - 0.075 12.8 16.1 0.085 12.6 11.2 1.1 1 0 0 1 1 1 0 DDHD domain Baculo_PP31 PF05311.6 CDI75962.1 - 0.08 12.1 14.0 0.091 12.0 9.7 1.1 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) CDC45 PF02724.9 CDI75962.1 - 0.1 10.6 12.9 0.11 10.5 8.9 1.0 1 0 0 1 1 1 0 CDC45-like protein CobT PF06213.7 CDI75962.1 - 0.13 11.3 13.0 0.18 10.9 9.0 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Herpes_DNAp_acc PF04929.7 CDI75962.1 - 0.33 9.8 13.2 0.32 9.9 9.2 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Zip PF02535.17 CDI75962.1 - 0.42 9.5 5.7 0.4 9.6 3.9 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Pneumo_phosprot PF02478.11 CDI75962.1 - 0.47 9.9 5.7 0.54 9.7 4.0 1.1 1 0 0 1 1 1 0 Pneumovirus phosphoprotein Hom_end_hint PF05203.11 CDI75962.1 - 0.47 10.1 10.1 0.56 9.8 7.0 1.3 1 0 0 1 1 1 0 Hom_end-associated Hint OATP PF03137.15 CDI75962.1 - 0.65 7.9 10.2 0.75 7.7 7.1 1.3 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Paf1 PF03985.8 CDI75962.1 - 0.71 8.5 22.3 0.81 8.3 15.5 1.1 1 0 0 1 1 1 0 Paf1 RP-C_C PF11800.3 CDI75962.1 - 0.79 9.3 19.3 0.99 9.0 13.4 1.1 1 0 0 1 1 1 0 Replication protein C C-terminal region DUF4045 PF13254.1 CDI75962.1 - 0.98 8.6 19.2 1.1 8.4 13.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) RR_TM4-6 PF06459.7 CDI75962.1 - 1.2 8.9 21.6 1.4 8.7 15.0 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CDK5_activator PF03261.10 CDI75962.1 - 1.2 8.3 15.7 1.1 8.4 10.9 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein AIF_C PF14721.1 CDI75962.1 - 1.2 9.3 17.6 1.8 8.7 12.2 1.3 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Med15 PF09606.5 CDI75962.1 - 1.3 7.1 66.6 1.3 7.1 46.2 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal FAM91_C PF14648.1 CDI75962.1 - 1.3 7.7 8.5 1.4 7.6 5.9 1.0 1 0 0 1 1 1 0 FAM91 C-terminus XRN_N PF03159.13 CDI75962.1 - 1.5 8.1 9.4 1.7 7.9 6.5 1.3 1 0 0 1 1 1 0 XRN 5'-3' exonuclease N-terminus DUF4220 PF13968.1 CDI75962.1 - 1.6 7.7 8.6 1.8 7.6 6.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4220) DUF3260 PF11658.3 CDI75962.1 - 1.6 6.7 16.7 1.7 6.7 11.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3260) SprA-related PF12118.3 CDI75962.1 - 1.7 7.9 47.6 2 7.6 33.0 1.1 1 0 0 1 1 1 0 SprA-related family Presenilin PF01080.12 CDI75962.1 - 1.7 7.3 13.8 1.9 7.2 9.6 1.1 1 0 0 1 1 1 0 Presenilin DUF966 PF06136.8 CDI75962.1 - 1.8 7.8 18.8 2.1 7.7 13.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) HD-ZIP_N PF04618.7 CDI75962.1 - 2 8.9 13.8 3 8.3 9.6 1.2 1 0 0 1 1 1 0 HD-ZIP protein N terminus DUF4638 PF15472.1 CDI75962.1 - 2.3 7.7 15.2 2.6 7.5 10.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) G-7-MTase PF12803.2 CDI75962.1 - 3.2 6.8 9.7 3.4 6.7 6.7 1.1 1 0 0 1 1 1 0 mRNA (guanine-7-)methyltransferase (G-7-MTase) SAGA-Tad1 PF12767.2 CDI75962.1 - 3.2 7.3 24.1 4.2 6.9 16.7 1.2 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit Membralin PF09746.4 CDI75962.1 - 3.3 6.6 8.0 3.3 6.6 5.6 1.1 1 0 0 1 1 1 0 Tumour-associated protein 5_nucleotid PF05761.9 CDI75962.1 - 3.4 6.0 14.9 4.1 5.8 10.3 1.1 1 0 0 1 1 1 0 5' nucleotidase family Gag_spuma PF03276.9 CDI75962.1 - 3.4 5.8 39.1 4.1 5.6 27.1 1.1 1 0 0 1 1 1 0 Spumavirus gag protein DUF1631 PF07793.6 CDI75962.1 - 3.6 5.5 32.7 4.2 5.3 22.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) DUF4407 PF14362.1 CDI75962.1 - 3.7 6.4 26.4 4.4 6.1 18.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Tim54 PF11711.3 CDI75962.1 - 3.8 6.0 16.3 4.5 5.7 11.3 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Folate_carrier PF01770.13 CDI75962.1 - 3.8 5.9 11.0 4.6 5.6 7.6 1.2 1 0 0 1 1 1 0 Reduced folate carrier CPSF100_C PF13299.1 CDI75962.1 - 3.9 7.6 19.7 5 7.2 13.6 1.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal BORG_CEP PF14957.1 CDI75962.1 - 4.3 8.2 13.6 6.2 7.7 9.5 1.3 1 0 0 1 1 1 0 Cdc42 effector Mem_trans PF03547.13 CDI75962.1 - 4.5 5.4 7.8 4.8 5.3 5.4 1.1 1 0 0 1 1 1 0 Membrane transport protein SID-1_RNA_chan PF13965.1 CDI75962.1 - 4.6 5.2 10.0 4.8 5.2 6.9 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 RIC3 PF15361.1 CDI75962.1 - 4.8 7.4 21.6 7 6.8 15.0 1.2 1 0 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 MMR1 PF08505.5 CDI75962.1 - 5.5 6.9 26.6 5.5 6.9 18.4 1.1 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein Med19 PF10278.4 CDI75962.1 - 5.7 6.5 12.9 7.5 6.1 8.9 1.2 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 Spore_coat_CotO PF14153.1 CDI75962.1 - 6.1 6.2 29.8 7.7 5.9 20.7 1.1 1 0 0 1 1 1 0 Spore coat protein CotO FAM60A PF15396.1 CDI75962.1 - 7 6.3 16.5 9 5.9 11.4 1.1 1 0 0 1 1 1 0 Protein Family FAM60A AAA_23 PF13476.1 CDI75962.1 - 8 6.7 26.0 8.8 6.5 18.0 1.1 1 0 0 1 1 1 0 AAA domain TFIIA PF03153.8 CDI75962.1 - 8 6.2 41.4 8.2 6.2 28.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Asp-B-Hydro_N PF05279.6 CDI75962.1 - 8.1 6.2 16.0 8.6 6.1 11.1 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region FYDLN_acid PF09538.5 CDI75962.1 - 8.5 7.0 11.3 14 6.3 7.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) SeqA PF03925.8 CDI75962.1 - 8.6 6.0 18.4 13 5.4 12.7 1.4 1 0 0 1 1 1 0 SeqA protein DUF913 PF06025.7 CDI75962.1 - 8.6 4.9 13.1 10 4.7 9.0 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) AUX_IAA PF02309.11 CDI75962.1 - 9.9 5.8 21.5 12 5.5 14.9 1.1 1 0 0 1 1 1 0 AUX/IAA family SR-25 PF10500.4 CDI75964.1 - 0.00078 18.9 10.3 0.00078 18.9 7.2 10.2 5 2 4 10 10 10 2 Nuclear RNA-splicing-associated protein Trypan_PARP PF05887.6 CDI75965.1 - 3.1 7.6 33.7 0.068 12.9 16.6 2.1 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) PP2C_2 PF13672.1 CDI75966.1 - 9.1e-07 28.4 0.0 2.8e-06 26.8 0.0 1.8 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 CDI75966.1 - 7.7e-06 25.7 0.0 7.2e-05 22.5 0.0 2.4 2 1 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) PP2C PF00481.16 CDI75966.1 - 0.0042 16.5 0.0 0.39 10.0 0.0 2.2 2 0 0 2 2 2 2 Protein phosphatase 2C SR-25 PF10500.4 CDI75966.1 - 0.007 15.8 9.9 0.014 14.9 6.9 1.4 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Tim54 PF11711.3 CDI75967.1 - 0.04 12.5 7.6 0.048 12.2 5.3 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Ycf1 PF05758.7 CDI75967.1 - 0.055 11.1 12.8 0.059 11.0 8.9 1.0 1 0 0 1 1 1 0 Ycf1 Cellulose_synt PF03552.9 CDI75967.1 - 0.068 11.4 4.8 0.072 11.3 3.3 1.0 1 0 0 1 1 1 0 Cellulose synthase FAM176 PF14851.1 CDI75967.1 - 0.074 12.7 2.5 0.1 12.2 1.8 1.3 1 0 0 1 1 1 0 FAM176 family YABBY PF04690.8 CDI75967.1 - 0.11 12.7 7.7 0.14 12.3 5.3 1.2 1 0 0 1 1 1 0 YABBY protein DDRGK PF09756.4 CDI75967.1 - 0.13 11.6 17.8 0.21 10.9 12.3 1.3 1 0 0 1 1 1 0 DDRGK domain Mem_trans PF03547.13 CDI75967.1 - 0.14 10.4 3.2 0.14 10.4 2.2 1.1 1 0 0 1 1 1 0 Membrane transport protein Zip PF02535.17 CDI75967.1 - 0.15 11.0 2.5 0.18 10.8 1.8 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter TMEM51 PF15345.1 CDI75967.1 - 0.18 11.4 13.2 0.23 11.1 9.1 1.4 1 0 0 1 1 1 0 Transmembrane protein 51 FLO_LFY PF01698.11 CDI75967.1 - 0.3 9.9 9.6 0.34 9.7 6.7 1.2 1 0 0 1 1 1 0 Floricaula / Leafy protein PBP1_TM PF14812.1 CDI75967.1 - 0.33 11.2 2.5 0.65 10.3 1.7 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Kei1 PF08552.6 CDI75967.1 - 0.42 10.2 7.8 0.63 9.6 5.4 1.4 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 BNR_3 PF13859.1 CDI75967.1 - 0.44 9.5 5.6 0.51 9.3 3.9 1.1 1 0 0 1 1 1 0 BNR repeat-like domain BTV_NS2 PF04514.7 CDI75967.1 - 0.72 8.6 10.7 0.85 8.4 7.4 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 SID-1_RNA_chan PF13965.1 CDI75967.1 - 0.72 7.9 7.3 0.68 8.0 5.1 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DUF775 PF05603.7 CDI75967.1 - 0.75 9.2 13.8 1 8.8 9.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF775) Rax2 PF12768.2 CDI75967.1 - 1.1 8.3 7.9 1.5 7.9 5.5 1.1 1 0 0 1 1 1 0 Cortical protein marker for cell polarity Hid1 PF12722.2 CDI75967.1 - 1.2 6.7 14.2 1.4 6.5 9.8 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF4045 PF13254.1 CDI75967.1 - 1.3 8.2 9.8 1.4 8.1 6.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) MMR1 PF08505.5 CDI75967.1 - 1.3 8.9 18.6 1.6 8.7 12.9 1.1 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein FAM60A PF15396.1 CDI75967.1 - 1.4 8.6 10.9 1.6 8.4 7.6 1.1 1 0 0 1 1 1 0 Protein Family FAM60A TFIIA PF03153.8 CDI75967.1 - 1.8 8.3 31.9 2.1 8.1 22.1 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit AIF_C PF14721.1 CDI75967.1 - 2.9 8.1 11.3 4.2 7.6 7.9 1.3 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term DUF4647 PF15504.1 CDI75967.1 - 3.1 6.5 20.2 3.8 6.2 14.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4647) Spc7_N PF15402.1 CDI75967.1 - 3.8 5.3 14.8 4.6 5.1 10.3 1.0 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 SDH_beta PF03315.10 CDI75967.1 - 4 7.4 8.4 5.6 6.9 5.8 1.2 1 0 0 1 1 1 0 Serine dehydratase beta chain DUF1800 PF08811.6 CDI75967.1 - 4.3 6.1 20.7 5.1 5.9 14.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1800) PAT1 PF09770.4 CDI75967.1 - 4.4 5.4 43.2 5.3 5.1 29.9 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Hom_end_hint PF05203.11 CDI75967.1 - 4.6 6.9 8.8 5.4 6.6 6.1 1.1 1 0 0 1 1 1 0 Hom_end-associated Hint Paramyxo_ncap PF00973.14 CDI75967.1 - 4.9 5.7 11.6 5.2 5.6 8.0 1.0 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein CD20 PF04103.10 CDI75967.1 - 6.4 6.6 7.1 15 5.4 4.8 1.9 1 1 0 1 1 1 0 CD20-like family DUF822 PF05687.8 CDI75967.1 - 9.4 6.5 10.8 14 6.0 7.5 1.3 1 0 0 1 1 1 0 Plant protein of unknown function (DUF822) Ldh_1_C PF02866.13 CDI75968.1 - 1.9e-26 92.8 0.0 1.9e-26 92.8 0.0 2.1 2 0 0 2 2 2 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.18 CDI75968.1 - 2.6e-24 85.6 0.9 1.8e-23 82.9 0.1 2.2 2 0 0 2 2 2 1 lactate/malate dehydrogenase, NAD binding domain Mucin PF01456.12 CDI75968.1 - 0.0034 17.1 9.6 0.0049 16.6 6.7 1.2 1 0 0 1 1 1 1 Mucin-like glycoprotein DSHCT PF08148.7 CDI75968.1 - 0.036 13.3 0.3 0.16 11.1 0.0 2.0 2 0 0 2 2 2 0 DSHCT (NUC185) domain DUF2360 PF10152.4 CDI75968.1 - 1.9 8.7 7.9 3.2 8.0 5.5 1.3 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) Med3 PF11593.3 CDI75968.1 - 2.7 7.1 14.7 3.8 6.6 10.2 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DUF3246 PF11596.3 CDI75972.1 - 0.027 13.7 5.3 0.036 13.3 3.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) BUD22 PF09073.5 CDI75972.1 - 1.1 8.2 8.8 1.3 7.9 6.1 1.1 1 0 0 1 1 1 0 BUD22 SDA1 PF05285.7 CDI75972.1 - 2.2 7.4 14.7 2.6 7.2 10.2 1.1 1 0 0 1 1 1 0 SDA1 PepSY_2 PF13670.1 CDI75972.1 - 6.5 6.7 18.7 0.67 9.8 1.9 2.8 3 0 0 3 3 3 0 Peptidase propeptide and YPEB domain SPT2 PF08243.6 CDI75972.1 - 9.2 6.6 19.2 1.6 9.0 6.8 2.1 2 0 0 2 2 2 0 SPT2 chromatin protein RskA PF10099.4 CDI75973.1 - 0.0016 18.1 5.5 0.0016 18.1 3.8 4.0 4 0 0 4 4 4 2 Anti-sigma-K factor rskA DUF1777 PF08648.7 CDI75973.1 - 0.0022 17.7 53.7 0.0022 17.7 37.2 6.5 3 2 2 5 5 5 1 Protein of unknown function (DUF1777) zf-RanBP PF00641.13 CDI75973.1 - 0.03 13.4 0.8 0.03 13.4 0.5 2.4 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others Spt20 PF12090.3 CDI75975.1 - 0.14 11.4 4.4 0.14 11.4 3.0 1.2 1 0 0 1 1 1 0 Spt20 family HXXEE PF13787.1 CDI75975.1 - 0.17 12.2 1.3 0.35 11.2 0.9 1.6 1 1 0 1 1 1 0 Protein of unknown function with HXXEE motif Mitofilin PF09731.4 CDI75975.1 - 1.2 7.7 21.9 1.3 7.5 15.2 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein FimP PF09766.4 CDI75975.1 - 1.2 8.0 6.9 1.5 7.7 4.8 1.1 1 0 0 1 1 1 0 Fms-interacting protein PAT1 PF09770.4 CDI75975.1 - 1.3 7.1 17.8 1.4 7.1 12.4 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Draxin PF15550.1 CDI75975.1 - 1.7 8.1 5.5 2.3 7.8 3.8 1.2 1 0 0 1 1 1 0 Draxin PIH1 PF08190.7 CDI75975.1 - 2 7.7 12.9 2.2 7.6 8.9 1.2 1 0 0 1 1 1 0 pre-RNA processing PIH1/Nop17 CCDC84 PF14968.1 CDI75975.1 - 2.2 7.7 7.3 2.5 7.5 5.1 1.0 1 0 0 1 1 1 0 Coiled coil protein 84 Hid1 PF12722.2 CDI75975.1 - 2.4 5.7 6.5 2.7 5.5 4.5 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Peptidase_S64 PF08192.6 CDI75975.1 - 4.5 5.4 10.7 5.1 5.3 7.4 1.0 1 0 0 1 1 1 0 Peptidase family S64 DUF1071 PF06378.6 CDI75975.1 - 5.7 6.0 6.9 11 5.0 4.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1071) vMSA PF00695.14 CDI75975.1 - 7.3 5.6 8.7 8.4 5.4 6.0 1.2 1 0 0 1 1 1 0 Major surface antigen from hepadnavirus SRP-alpha_N PF04086.8 CDI75975.1 - 8.1 5.7 8.9 9.2 5.5 6.2 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal GDI PF00996.13 CDI75979.1 - 8.8e-33 113.2 6.6 6.5e-32 110.4 4.6 2.1 1 1 0 1 1 1 1 GDP dissociation inhibitor SAPS PF04499.10 CDI75979.1 - 9.2e-05 21.2 15.4 0.0001 21.0 10.7 1.1 1 0 0 1 1 1 1 SIT4 phosphatase-associated protein Nha1_C PF08619.5 CDI75979.1 - 0.032 13.4 27.4 0.043 13.1 19.0 1.0 1 0 0 1 1 1 0 Alkali metal cation/H+ antiporter Nha1 C terminus LMBR1 PF04791.11 CDI75979.1 - 0.098 11.2 12.6 0.18 10.3 8.8 1.4 1 1 0 1 1 1 0 LMBR1-like membrane protein Hid1 PF12722.2 CDI75979.1 - 0.26 8.9 31.4 0.31 8.6 21.8 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein GAGA_bind PF06217.7 CDI75979.1 - 2 8.2 34.1 2.9 7.7 23.6 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family Herpes_DNAp_acc PF04929.7 CDI75979.1 - 2.9 6.7 25.7 5.5 5.8 17.8 1.4 1 0 0 1 1 1 0 Herpes DNA replication accessory factor PAT1 PF09770.4 CDI75979.1 - 4 5.5 92.3 5.1 5.1 64.0 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SR-25 PF10500.4 CDI75983.1 - 0.0026 17.2 20.9 0.0026 17.2 14.5 8.6 3 2 6 9 9 9 2 Nuclear RNA-splicing-associated protein HSP70 PF00012.15 CDI75984.1 - 4.6e-12 44.6 3.6 4.6e-12 44.6 2.5 6.6 2 1 3 5 5 5 1 Hsp70 protein CAF-1_p150 PF11600.3 CDI75984.1 - 5.5e-05 22.6 27.0 5.5e-05 22.6 18.7 4.1 3 1 0 4 4 4 2 Chromatin assembly factor 1 complex p150 subunit, N-terminal AAA_23 PF13476.1 CDI75985.1 - 0.47 10.7 12.2 0.34 11.2 3.6 2.3 2 0 0 2 2 2 0 AAA domain TMEM247 PF15444.1 CDI75987.1 - 0.0012 18.6 0.6 0.0012 18.6 0.4 6.1 7 0 0 7 7 7 1 Transmembrane protein 247 SprA-related PF12118.3 CDI75987.1 - 0.0017 17.7 19.4 0.0017 17.7 13.5 11.7 9 5 1 10 10 10 1 SprA-related family RskA PF10099.4 CDI75987.1 - 0.015 15.0 0.2 0.015 15.0 0.1 16.8 10 6 6 17 17 17 0 Anti-sigma-K factor rskA SR-25 PF10500.4 CDI75989.1 - 0.0024 17.3 2.0 0.0024 17.3 1.4 3.1 3 0 0 3 3 3 1 Nuclear RNA-splicing-associated protein PAT1 PF09770.4 CDI75989.1 - 0.016 13.4 101.2 0.019 13.2 70.1 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Di19_C PF14571.1 CDI75989.1 - 0.018 15.3 6.6 0.018 15.3 4.6 3.7 2 1 0 3 3 3 0 Stress-induced protein Di19, C-terminal FLO_LFY PF01698.11 CDI75991.1 - 0.0046 15.8 10.8 0.0046 15.8 7.5 2.2 2 0 0 2 2 2 1 Floricaula / Leafy protein Suf PF05843.9 CDI75991.1 - 0.0086 15.8 35.4 0.035 13.8 13.6 2.3 2 0 0 2 2 2 2 Suppressor of forked protein (Suf) DUF1510 PF07423.6 CDI75991.1 - 0.014 14.7 23.7 0.028 13.7 10.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) Ycf1 PF05758.7 CDI75991.1 - 0.67 7.5 21.2 1.4 6.4 10.1 2.0 2 0 0 2 2 2 0 Ycf1 SAGA-Tad1 PF12767.2 CDI75991.1 - 2.6 7.6 32.0 0.69 9.5 2.1 2.2 2 0 0 2 2 2 0 Transcriptional regulator of RNA polII, SAGA, subunit GAGA_bind PF06217.7 CDI75991.1 - 2.8 7.8 28.1 2.1 8.2 12.8 2.1 2 0 0 2 2 2 0 GAGA binding protein-like family DUF2052 PF09747.4 CDI75991.1 - 3.4 7.5 40.2 0.48 10.3 2.8 2.1 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) Gti1_Pac2 PF09729.4 CDI75991.1 - 4.9 6.9 21.6 3.2 7.5 0.2 2.2 2 0 0 2 2 2 0 Gti1/Pac2 family Dynamin_N PF00350.18 CDI75991.1 - 5.2 6.8 12.8 2.5 7.8 3.2 2.4 2 0 0 2 2 2 0 Dynamin family Herpes_DNAp_acc PF04929.7 CDI75991.1 - 7.3 5.4 22.1 1.3 7.9 8.8 2.3 2 0 0 2 2 2 0 Herpes DNA replication accessory factor eIF-3_zeta PF05091.7 CDI75991.1 - 7.5 5.0 37.7 1.3 7.5 1.9 2.1 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) SID-1_RNA_chan PF13965.1 CDI75991.1 - 9.8 4.1 13.0 3 5.8 4.2 2.2 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 rve PF00665.21 CDI75992.1 - 1.8e-11 44.1 0.0 3.6e-11 43.2 0.0 1.6 2 0 0 2 2 2 1 Integrase core domain Chromo PF00385.19 CDI75992.1 - 6.4e-05 22.5 0.0 0.35 10.5 0.0 2.6 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain rve_3 PF13683.1 CDI75992.1 - 0.09 12.3 0.1 0.19 11.2 0.1 1.5 1 0 0 1 1 1 0 Integrase core domain Hydrolase_4 PF12146.3 CDI75992.1 - 0.2 11.5 0.9 17 5.3 0.0 3.0 2 1 0 3 3 3 0 Putative lysophospholipase DUF1360 PF07098.6 CDI75993.1 - 0.82 9.4 12.1 9.4 6.0 0.0 5.2 4 0 0 4 4 4 0 Protein of unknown function (DUF1360) Med15 PF09606.5 CDI75994.1 - 6.7 4.7 98.8 9.6 4.2 68.5 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF2392 PF10288.4 CDI75996.1 - 6.5e-05 23.2 0.0 0.00015 22.0 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2392) Pox_Ag35 PF03286.9 CDI75996.1 - 0.085 12.3 0.8 0.14 11.6 0.6 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein UPF0560 PF10577.4 CDI75996.1 - 0.17 10.1 6.2 0.21 9.8 4.3 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 PAT1 PF09770.4 CDI75996.1 - 0.17 10.0 13.2 0.22 9.7 9.2 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF4175 PF13779.1 CDI75996.1 - 0.71 7.4 16.0 0.99 7.0 11.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) CLAG PF03805.8 CDI75997.1 - 0.00053 17.5 0.0 0.0012 16.3 0.0 1.5 1 0 0 1 1 1 1 Cytoadherence-linked asexual protein PmbA_TldD PF01523.11 CDI75999.1 - 0.11 11.7 5.9 0.21 10.8 4.1 1.5 1 0 0 1 1 1 0 Putative modulator of DNA gyrase CENP-T PF15511.1 CDI75999.1 - 0.2 10.8 8.8 0.27 10.4 6.1 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Effector_1 PF04518.7 CDI75999.1 - 1.1 8.2 5.5 1.3 7.9 3.8 1.1 1 0 0 1 1 1 0 Effector from type III secretion system Activator_LAG-3 PF11498.3 CDI76000.1 - 5.1e-05 22.2 8.3 5.1e-05 22.2 5.8 4.3 4 0 0 4 4 4 2 Transcriptional activator LAG-3 EphA2_TM PF14575.1 CDI76000.1 - 0.02 15.2 9.1 1.6 9.1 0.1 3.6 3 0 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain Spt20 PF12090.3 CDI76000.1 - 0.026 13.8 0.0 0.026 13.8 0.0 3.8 2 1 0 2 2 2 0 Spt20 family CD20 PF04103.10 CDI76000.1 - 0.077 12.9 10.4 1.7 8.5 0.0 3.9 4 0 0 4 4 4 0 CD20-like family zf-DHHC PF01529.15 CDI76000.1 - 0.53 9.6 5.6 5.9 6.2 0.0 3.0 2 1 1 3 3 3 0 DHHC palmitoyltransferase RAB3GAP2_N PF14655.1 CDI76000.1 - 1.1 8.1 28.1 0.22 10.4 2.5 3.8 4 0 0 4 4 4 0 Rab3 GTPase-activating protein regulatory subunit N-terminus 7tm_1 PF00001.16 CDI76000.1 - 1.8 7.6 10.3 1.9 7.5 2.5 3.1 2 1 0 2 2 2 0 7 transmembrane receptor (rhodopsin family) Apc1 PF12859.2 CDI76000.1 - 4.2 7.6 16.4 2.1 8.5 0.5 4.1 4 0 0 4 4 4 0 Anaphase-promoting complex subunit 1 CDC27 PF09507.5 CDI76001.1 - 0.1 11.8 32.0 0.13 11.4 22.2 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 DUF566 PF04484.7 CDI76001.1 - 0.21 11.0 19.4 0.29 10.6 13.4 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF566) DUF4614 PF15391.1 CDI76001.1 - 0.35 10.6 13.6 0.63 9.7 9.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) DNA_pol_viral_N PF00242.12 CDI76001.1 - 0.57 9.1 15.0 0.83 8.6 10.4 1.2 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain Corona_nucleoca PF00937.13 CDI76001.1 - 1.1 8.1 12.6 1.2 7.9 8.7 1.2 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein MDFI PF15316.1 CDI76001.1 - 2.6 8.0 8.6 4.8 7.1 5.9 1.4 1 0 0 1 1 1 0 MyoD family inhibitor Ndc1_Nup PF09531.5 CDI76001.1 - 4.7 5.5 9.0 5.4 5.3 6.2 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Aminotran_5 PF00266.14 CDI76002.1 - 3.2e-29 101.8 0.0 1.3e-14 53.7 0.0 2.2 1 1 1 2 2 2 2 Aminotransferase class-V RAB3GAP2_N PF14655.1 CDI76002.1 - 0.011 14.8 2.8 0.016 14.2 1.9 1.1 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Spt20 PF12090.3 CDI76002.1 - 0.011 15.0 0.0 0.015 14.6 0.0 1.2 1 0 0 1 1 1 0 Spt20 family Suf PF05843.9 CDI76002.1 - 0.085 12.5 2.1 0.15 11.7 1.5 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) TGT PF01702.13 CDI76003.1 - 3e-10 39.8 0.2 3e-10 39.8 0.1 3.0 3 0 0 3 3 3 1 Queuine tRNA-ribosyltransferase BAF1_ABF1 PF04684.8 CDI76003.1 - 0.00052 18.9 14.9 0.00052 18.9 10.4 9.6 8 3 2 10 10 10 1 BAF1 / ABF1 chromatin reorganising factor RskA PF10099.4 CDI76003.1 - 0.00076 19.2 1.3 0.00076 19.2 0.9 9.6 5 3 1 7 7 7 2 Anti-sigma-K factor rskA Ribosomal_60s PF00428.14 CDI76003.1 - 0.0036 17.6 8.3 0.0036 17.6 5.7 9.1 8 2 1 9 9 9 4 60s Acidic ribosomal protein Herpes_MCP PF03122.9 CDI76004.1 - 0.01 13.2 6.5 0.011 13.1 4.5 1.0 1 0 0 1 1 1 0 Herpes virus major capsid protein MSA-2c PF12238.3 CDI76004.1 - 0.15 11.6 8.0 0.23 11.0 5.5 1.4 1 0 0 1 1 1 0 Merozoite surface antigen 2c IL3 PF02059.10 CDI76004.1 - 0.29 11.1 4.9 0.47 10.4 3.4 1.4 1 0 0 1 1 1 0 Interleukin-3 FemAB PF02388.11 CDI76004.1 - 0.93 8.1 15.1 0.99 8.0 10.5 1.2 1 0 0 1 1 1 0 FemAB family XRN_N PF03159.13 CDI76004.1 - 1.1 8.5 9.3 1.3 8.3 6.4 1.2 1 0 0 1 1 1 0 XRN 5'-3' exonuclease N-terminus SMN PF06003.7 CDI76004.1 - 1.6 7.7 5.4 1.9 7.5 3.8 1.2 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) CDC45 PF02724.9 CDI76004.1 - 1.6 6.6 19.4 1.7 6.6 13.4 1.0 1 0 0 1 1 1 0 CDC45-like protein Baculo_PP31 PF05311.6 CDI76004.1 - 2 7.6 14.0 3.1 6.9 9.7 1.3 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) Zip PF02535.17 CDI76004.1 - 2.1 7.2 6.8 2.5 7.0 4.7 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter SAPS PF04499.10 CDI76004.1 - 2.3 6.7 16.9 2.2 6.8 11.7 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF4638 PF15472.1 CDI76004.1 - 2.3 7.7 11.3 2.5 7.6 7.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) Peptidase_S21 PF00716.12 CDI76004.1 - 2.6 7.3 13.1 3.1 7.0 9.1 1.1 1 0 0 1 1 1 0 Assemblin (Peptidase family S21) Folate_carrier PF01770.13 CDI76004.1 - 3.2 6.1 7.1 3.8 5.9 4.9 1.2 1 0 0 1 1 1 0 Reduced folate carrier Mem_trans PF03547.13 CDI76004.1 - 5.1 5.2 4.9 5.6 5.1 3.4 1.2 1 0 0 1 1 1 0 Membrane transport protein Plasmodium_Vir PF05795.6 CDI76004.1 - 5.2 6.1 6.7 5.2 6.1 4.7 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein DUF853 PF05872.7 CDI76004.1 - 5.6 5.1 13.1 7.2 4.8 9.1 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) Glyco_transf_15 PF01793.11 CDI76004.1 - 5.9 5.7 12.9 8.7 5.1 8.9 1.3 1 0 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase Anoctamin PF04547.7 CDI76004.1 - 6.1 5.3 9.9 7.3 5.1 6.8 1.2 1 0 0 1 1 1 0 Calcium-activated chloride channel LMBR1 PF04791.11 CDI76004.1 - 6.2 5.2 8.7 6.4 5.2 6.0 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein PCEMA1 PF07418.6 CDI76004.1 - 7.7 5.7 9.7 8.7 5.6 6.7 1.2 1 0 0 1 1 1 0 Acidic phosphoprotein precursor PCEMA1 Ycf1 PF05758.7 CDI76004.1 - 8.9 3.8 16.6 8.9 3.8 11.5 1.1 1 0 0 1 1 1 0 Ycf1 DHHW PF14286.1 CDI76004.1 - 9.2 5.4 12.9 11 5.1 8.9 1.2 1 0 0 1 1 1 0 DHHW protein DNA_pol3_delta PF06144.8 CDI76005.1 - 0.034 13.6 0.0 0.046 13.2 0.0 1.2 1 0 0 1 1 1 0 DNA polymerase III, delta subunit Bac_DnaA PF00308.13 CDI76005.1 - 0.12 12.0 0.1 0.15 11.6 0.1 1.1 1 0 0 1 1 1 0 Bacterial dnaA protein DUF2142 PF09913.4 CDI76006.1 - 0.00088 18.0 10.3 0.0012 17.5 7.1 1.2 1 0 0 1 1 1 1 Predicted membrane protein (DUF2142) LMBR1 PF04791.11 CDI76006.1 - 0.0051 15.4 0.2 0.0067 15.0 0.2 1.3 1 1 0 1 1 1 1 LMBR1-like membrane protein Cellulose_synt PF03552.9 CDI76006.1 - 0.45 8.7 5.6 0.54 8.4 3.9 1.3 1 0 0 1 1 1 0 Cellulose synthase Cwf_Cwc_15 PF04889.7 CDI76006.1 - 0.65 9.6 29.9 1.1 8.9 20.7 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein YjgP_YjgQ PF03739.9 CDI76006.1 - 0.68 8.6 9.5 1.1 7.8 6.6 1.4 1 1 0 1 1 1 0 Predicted permease YjgP/YjgQ family Bud13 PF09736.4 CDI76006.1 - 0.85 9.8 25.7 1.4 9.1 17.8 1.4 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex Spore_coat_CotO PF14153.1 CDI76006.1 - 0.88 8.9 30.1 1.9 7.9 20.9 1.5 1 0 0 1 1 1 0 Spore coat protein CotO CDC45 PF02724.9 CDI76006.1 - 2.1 6.2 22.2 3.5 5.5 15.4 1.3 1 0 0 1 1 1 0 CDC45-like protein DUF1635 PF07795.6 CDI76006.1 - 2.3 7.5 25.1 3.7 6.8 17.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) Hid1 PF12722.2 CDI76006.1 - 2.4 5.7 31.2 3.8 5.0 21.6 1.3 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Dapper PF15268.1 CDI76006.1 - 2.7 6.6 38.8 3.3 6.3 26.9 1.0 1 0 0 1 1 1 0 Dapper SAGA-Tad1 PF12767.2 CDI76006.1 - 4.9 6.7 30.2 7.7 6.0 20.9 1.3 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit NABP PF07990.7 CDI76006.1 - 9.7 5.3 33.1 12 4.9 22.9 1.1 1 0 0 1 1 1 0 Nucleic acid binding protein NABP Ribosomal_60s PF00428.14 CDI76007.1 - 0.017 15.4 9.2 0.029 14.7 6.4 1.3 1 0 0 1 1 1 0 60s Acidic ribosomal protein CobT PF06213.7 CDI76007.1 - 0.04 13.0 2.0 0.045 12.8 1.4 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Mem_trans PF03547.13 CDI76007.1 - 0.048 11.9 0.8 0.057 11.6 0.5 1.2 1 0 0 1 1 1 0 Membrane transport protein Nop14 PF04147.7 CDI76007.1 - 0.32 8.8 5.5 0.41 8.4 3.8 1.1 1 0 0 1 1 1 0 Nop14-like family Presenilin PF01080.12 CDI76007.1 - 0.4 9.4 2.3 0.42 9.3 1.6 1.2 1 0 0 1 1 1 0 Presenilin Apt1 PF10351.4 CDI76007.1 - 2 7.1 15.8 2.5 6.8 11.0 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF2217 PF10265.4 CDI76007.1 - 7.8 5.1 12.1 9.3 4.8 8.4 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) DUF755 PF05501.6 CDI76009.1 - 0.00065 19.7 17.8 0.00065 19.7 12.3 7.0 6 1 1 7 7 7 1 Domain of unknown function (DUF755) SR-25 PF10500.4 CDI76009.1 - 0.0071 15.8 9.8 0.0071 15.8 6.8 6.0 5 1 1 6 6 6 1 Nuclear RNA-splicing-associated protein DUF912 PF06024.7 CDI76009.1 - 0.012 15.6 3.0 0.012 15.6 2.1 6.9 5 2 2 7 7 7 0 Nucleopolyhedrovirus protein of unknown function (DUF912) HTH_35 PF13693.1 CDI76009.1 - 0.56 10.0 7.3 1.2 8.9 0.0 3.2 3 0 0 3 3 3 0 Winged helix-turn-helix DNA-binding Ribosomal_60s PF00428.14 CDI76011.1 - 0.25 11.7 14.8 0.26 11.6 4.2 2.4 2 0 0 2 2 2 0 60s Acidic ribosomal protein MIP-T3 PF10243.4 CDI76012.1 - 0.00031 19.3 73.9 0.00031 19.3 51.2 3.5 2 2 0 2 2 2 1 Microtubule-binding protein MIP-T3 BRCT PF00533.21 CDI76012.1 - 0.0013 18.8 0.0 0.0028 17.7 0.0 1.5 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain P12 PF12669.2 CDI76014.1 - 0.0016 18.5 5.3 0.0016 18.5 3.7 4.4 4 1 0 4 4 4 1 Virus attachment protein p12 family Sporozoite_P67 PF05642.6 CDI76018.1 - 0.033 12.0 0.3 0.047 11.5 0.2 1.4 1 1 0 1 1 1 0 Sporozoite P67 surface antigen PMSR PF01625.16 CDI76018.1 - 0.043 13.6 1.8 0.073 12.9 1.3 1.3 1 0 0 1 1 1 0 Peptide methionine sulfoxide reductase zf-DHHC PF01529.15 CDI76022.1 - 0.099 12.0 0.3 0.09 12.1 0.2 1.2 1 0 0 1 1 1 0 DHHC palmitoyltransferase AAA_23 PF13476.1 CDI76022.1 - 0.13 12.5 13.8 0.14 12.4 9.6 1.2 1 0 0 1 1 1 0 AAA domain DUF2215 PF10225.4 CDI76022.1 - 5.6 6.3 7.0 9 5.6 4.8 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) Spt20 PF12090.3 CDI76032.1 - 0.00048 19.5 5.5 0.00048 19.5 3.8 2.3 2 0 0 2 2 2 1 Spt20 family FCP1_C PF09309.5 CDI76032.1 - 0.00078 18.8 22.5 0.047 12.9 5.9 2.5 2 0 0 2 2 2 2 FCP1, C-terminal FimP PF09766.4 CDI76032.1 - 0.0022 17.1 39.3 0.1 11.6 9.9 2.1 2 0 0 2 2 2 2 Fms-interacting protein Pex14_N PF04695.8 CDI76032.1 - 0.0053 16.8 7.0 0.0053 16.8 4.8 3.4 2 1 1 3 3 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF2052 PF09747.4 CDI76032.1 - 0.029 14.2 29.9 0.37 10.7 5.1 2.1 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) DUF4207 PF13904.1 CDI76032.1 - 0.03 13.7 42.7 0.019 14.3 8.3 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4207) TMEM51 PF15345.1 CDI76032.1 - 0.037 13.7 29.0 0.12 12.0 5.5 2.3 2 0 0 2 2 2 0 Transmembrane protein 51 DUF4557 PF15101.1 CDI76032.1 - 0.22 11.3 41.0 0.066 13.0 8.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4557) MRP-S31 PF15433.1 CDI76032.1 - 0.25 10.7 25.3 1.1 8.6 7.2 2.2 2 0 0 2 2 2 0 Mitochondrial 28S ribosomal protein S31 Gti1_Pac2 PF09729.4 CDI76032.1 - 0.29 11.0 14.9 0.9 9.3 1.9 2.4 2 0 0 2 2 2 0 Gti1/Pac2 family DUF4175 PF13779.1 CDI76032.1 - 0.33 8.5 66.2 0.62 7.6 16.9 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4175) Serinc PF03348.10 CDI76032.1 - 0.39 9.3 23.0 1 7.9 6.3 2.1 2 0 0 2 2 2 0 Serine incorporator (Serinc) Dehydrin PF00257.14 CDI76032.1 - 0.41 10.9 23.5 0.072 13.4 3.1 2.5 2 0 0 2 2 2 0 Dehydrin DUF1266 PF06889.6 CDI76032.1 - 0.42 10.3 17.8 1.8 8.3 4.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1266) FLO_LFY PF01698.11 CDI76032.1 - 0.53 9.0 22.0 1.2 7.9 4.4 2.1 2 0 0 2 2 2 0 Floricaula / Leafy protein NARP1 PF12569.3 CDI76032.1 - 0.85 8.2 29.7 0.23 10.1 3.3 2.1 2 0 0 2 2 2 0 NMDA receptor-regulated protein 1 Dynamin_N PF00350.18 CDI76032.1 - 1 9.1 10.8 1 9.1 0.7 2.4 2 0 0 2 2 2 0 Dynamin family DUF4045 PF13254.1 CDI76032.1 - 1.1 8.5 30.6 1.9 7.6 5.8 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4045) DUF1510 PF07423.6 CDI76032.1 - 1.1 8.5 27.2 2.4 7.4 6.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) Tim54 PF11711.3 CDI76032.1 - 1.2 7.5 19.3 1.5 7.3 3.8 2.1 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 Spore_coat_CotO PF14153.1 CDI76032.1 - 1.3 8.3 39.2 0.51 9.7 8.0 2.2 2 0 0 2 2 2 0 Spore coat protein CotO MAT1 PF06391.8 CDI76032.1 - 1.4 8.4 38.8 0.49 9.9 7.4 2.1 2 0 0 2 2 2 0 CDK-activating kinase assembly factor MAT1 DUF4355 PF14265.1 CDI76032.1 - 1.6 8.6 38.7 1.5 8.7 6.7 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4355) DUF3449 PF11931.3 CDI76032.1 - 1.7 8.1 25.9 1.8 8.0 4.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3449) Isy1 PF06246.7 CDI76032.1 - 2.3 7.5 28.0 0.17 11.2 3.8 2.1 2 0 0 2 2 2 0 Isy1-like splicing family Folliculin PF11704.3 CDI76032.1 - 2.3 7.7 19.4 3.5 7.1 2.7 2.3 2 0 0 2 2 2 0 Vesicle coat protein involved in Golgi to plasma membrane transport PAXIP1_C PF15364.1 CDI76032.1 - 2.4 8.0 26.7 0.82 9.5 6.2 2.2 2 0 0 2 2 2 0 PAXIP1-associated-protein-1 C term PTIP binding protein NMDAR2_C PF10565.4 CDI76032.1 - 2.9 6.4 23.0 2.5 6.6 4.5 2.2 2 0 0 2 2 2 0 N-methyl D-aspartate receptor 2B3 C-terminus AAT PF03417.11 CDI76032.1 - 2.9 7.2 14.8 0.67 9.3 2.2 2.2 2 0 0 2 2 2 0 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase Otopetrin PF03189.8 CDI76032.1 - 3 6.7 10.9 1.7 7.5 0.5 2.1 2 0 0 2 2 2 0 Otopetrin Peptidase_C58 PF03543.9 CDI76032.1 - 3.2 7.1 27.8 1.9 7.9 6.1 2.2 2 0 0 2 2 2 0 Yersinia/Haemophilus virulence surface antigen CKAP2_C PF15297.1 CDI76032.1 - 3.4 6.3 28.0 1.2 7.8 5.7 2.1 2 0 0 2 2 2 0 Cytoskeleton-associated protein 2 C-terminus Dala_Dala_lig_N PF01820.16 CDI76032.1 - 3.6 7.9 17.8 3 8.1 2.4 2.4 2 0 0 2 2 2 0 D-ala D-ala ligase N-terminus Afi1 PF07792.7 CDI76032.1 - 3.7 7.5 21.1 6.1 6.8 4.2 2.4 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking DUF572 PF04502.8 CDI76032.1 - 5.8 6.0 31.6 1.3 8.1 6.6 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF572) SRP-alpha_N PF04086.8 CDI76032.1 - 6.7 6.0 29.8 3.5 6.9 5.5 2.1 2 0 0 2 2 2 0 Signal recognition particle, alpha subunit, N-terminal Hid1 PF12722.2 CDI76032.1 - 7 4.1 28.5 1.7 6.2 6.4 2.0 2 0 0 2 2 2 0 High-temperature-induced dauer-formation protein Tom22 PF04281.8 CDI76032.1 - 7.5 6.0 18.0 1.2 8.7 2.5 2.5 2 0 0 2 2 2 0 Mitochondrial import receptor subunit Tom22 CDC45 PF02724.9 CDI76032.1 - 7.6 4.4 26.9 0.8 7.6 6.3 2.1 2 0 0 2 2 2 0 CDC45-like protein Peptidase_S49_N PF08496.5 CDI76032.1 - 8 6.2 26.5 2.1 8.1 3.9 2.2 2 0 0 2 2 2 0 Peptidase family S49 N-terminal AAA_11 PF13086.1 CDI76032.1 - 8 5.9 25.8 3 7.3 3.6 2.1 2 0 0 2 2 2 0 AAA domain Herpes_UL87 PF03043.9 CDI76032.1 - 8.6 4.6 15.2 17 3.6 10.5 1.4 1 1 0 1 1 1 0 Herpesvirus UL87 family DUF1644 PF07800.7 CDI76032.1 - 9.7 6.0 17.0 8.4 6.2 4.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1644) Raftlin PF15250.1 CDI76032.1 - 9.9 4.5 25.6 1.1 7.7 5.1 2.1 2 0 0 2 2 2 0 Raftlin PAT1 PF09770.4 CDI76034.1 - 0.076 11.2 137.4 0.13 10.5 52.8 2.2 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 DUF177 PF02620.12 CDI76052.1 - 0.095 12.7 2.0 0.1 12.6 0.1 2.0 2 0 0 2 2 2 0 Uncharacterized ACR, COG1399 Med15 PF09606.5 CDI76052.1 - 0.22 9.7 56.8 0.0063 14.7 31.8 2.1 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal Med19 PF10278.4 CDI76052.1 - 9.4 5.8 13.7 21 4.7 5.9 2.4 2 0 0 2 2 2 0 Mediator of RNA pol II transcription subunit 19 PRCH PF03967.8 CDI76052.1 - 9.7 5.7 7.6 2.2 7.8 1.1 2.4 2 0 0 2 2 2 0 Photosynthetic reaction centre, H-chain N-terminal region O-antigen_lig PF13425.1 CDI76066.1 - 0.029 14.3 0.0 0.041 13.8 0.0 1.1 1 0 0 1 1 1 0 O-antigen ligase like membrane protein DUF2919 PF11143.3 CDI76066.1 - 0.11 12.3 3.3 0.19 11.5 2.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2919) 2HCT PF03390.10 CDI76066.1 - 0.81 8.0 4.5 0.41 8.9 1.8 1.5 1 1 0 1 1 1 0 2-hydroxycarboxylate transporter family FAM60A PF15396.1 CDI76074.1 - 0.42 10.3 34.4 0.55 9.9 23.9 1.1 1 0 0 1 1 1 0 Protein Family FAM60A SAPS PF04499.10 CDI76074.1 - 0.91 8.0 34.5 1 7.9 23.9 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein CDC45 PF02724.9 CDI76074.1 - 5.6 4.8 43.3 6.3 4.7 30.0 1.0 1 0 0 1 1 1 0 CDC45-like protein VID27 PF08553.5 CDI76074.1 - 7.2 4.7 34.7 7.7 4.6 24.1 1.0 1 0 0 1 1 1 0 VID27 cytoplasmic protein Utp14 PF04615.8 CDI76074.1 - 7.4 4.5 49.8 8.6 4.3 34.5 1.0 1 0 0 1 1 1 0 Utp14 protein DUF1777 PF08648.7 CDI76074.1 - 9.1 5.9 30.0 12 5.5 20.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) CENP-T PF15511.1 CDI76074.1 - 9.8 5.2 38.5 12 5.0 26.7 1.0 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Hid1 PF12722.2 CDI76074.1 - 10 3.6 46.2 11 3.5 32.0 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein FYDLN_acid PF09538.5 CDI76082.1 - 0.5 10.9 27.1 0.6 10.7 18.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) RNA_pol_3_Rpc31 PF11705.3 CDI76082.1 - 0.83 9.5 33.4 1.2 9.0 23.2 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Ribosomal_60s PF00428.14 CDI76082.1 - 0.91 9.9 59.9 0.15 12.4 23.6 2.1 1 1 1 2 2 1 0 60s Acidic ribosomal protein MIP-T3 PF10243.4 CDI76082.1 - 1.7 7.0 25.2 1.9 6.8 17.5 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 CDC45 PF02724.9 CDI76082.1 - 2.4 6.0 29.3 2.7 5.9 20.3 1.0 1 0 0 1 1 1 0 CDC45-like protein TFIIA PF03153.8 CDI76082.1 - 2.6 7.8 26.0 2.8 7.7 18.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF2796 PF10986.3 CDI76082.1 - 2.8 7.9 15.4 3.7 7.5 10.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2796) DUF2052 PF09747.4 CDI76082.1 - 3.2 7.6 25.5 4.2 7.2 17.7 1.2 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) Pox_Ag35 PF03286.9 CDI76082.1 - 4.6 6.7 22.9 5.3 6.5 15.9 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein FLO_LFY PF01698.11 CDI76082.1 - 4.7 5.9 17.3 5.2 5.8 12.0 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein DDHD PF02862.12 CDI76082.1 - 8.8 6.0 15.0 11 5.7 10.4 1.0 1 0 0 1 1 1 0 DDHD domain Spore_coat_CotO PF14153.1 CDI76082.1 - 9.2 5.6 26.2 10 5.4 18.1 1.1 1 0 0 1 1 1 0 Spore coat protein CotO Daxx PF03344.10 CDI76082.1 - 9.4 4.5 37.2 10 4.4 25.8 1.0 1 0 0 1 1 1 0 Daxx Family CDK5_activator PF03261.10 CDI76088.1 - 0.017 14.4 7.1 0.022 14.0 4.9 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein CDC27 PF09507.5 CDI76088.1 - 1.5 7.9 41.6 1.9 7.6 28.8 1.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Na_trans_assoc PF06512.8 CDI76088.1 - 1.9 8.3 29.9 2.4 8.0 20.8 1.1 1 0 0 1 1 1 0 Sodium ion transport-associated Pox_Ag35 PF03286.9 CDI76088.1 - 9.5 5.6 39.9 1.1 8.7 9.0 2.1 1 1 1 2 2 2 0 Pox virus Ag35 surface protein SKIP_SNW PF02731.10 CDI76090.1 - 6.1e-16 58.2 7.6 6.1e-16 58.2 5.3 2.1 2 0 0 2 2 2 1 SKIP/SNW domain Spore_coat_CotO PF14153.1 CDI76090.1 - 0.16 11.4 4.9 0.18 11.2 3.4 1.2 1 0 0 1 1 1 0 Spore coat protein CotO CAF-1_p150 PF11600.3 CDI76090.1 - 6.3 6.1 24.3 8.2 5.7 16.9 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Abhydrolase_2 PF02230.11 CDI76091.1 - 1.8e-49 168.1 0.0 3.6e-49 167.1 0.0 1.5 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 CDI76091.1 - 2.3e-08 33.9 0.0 2.3e-08 33.9 0.0 2.4 2 1 0 2 2 2 1 Alpha/beta hydrolase family SET PF00856.23 CDI76091.1 - 7.3e-07 29.6 0.0 0.036 14.3 0.0 2.7 2 0 0 2 2 2 2 SET domain Abhydrolase_6 PF12697.2 CDI76091.1 - 1.2e-05 25.2 0.2 1.2e-05 25.2 0.2 4.1 4 2 1 5 5 5 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 CDI76091.1 - 0.0024 17.4 0.0 0.016 14.7 0.0 2.3 1 1 1 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 CDI76091.1 - 0.0027 16.9 0.1 0.27 10.4 0.0 2.5 2 0 0 2 2 2 1 Prolyl oligopeptidase family FSH1 PF03959.8 CDI76091.1 - 0.024 14.1 0.0 0.054 12.9 0.0 1.5 1 0 0 1 1 1 0 Serine hydrolase (FSH1) HA PF03457.9 CDI76091.1 - 0.031 14.3 0.5 0.1 12.7 0.3 1.8 1 0 0 1 1 1 0 Helicase associated domain Abhydrolase_1 PF00561.15 CDI76091.1 - 0.057 12.9 0.0 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold AXE1 PF05448.7 CDI76091.1 - 0.17 10.3 0.0 0.35 9.3 0.0 1.4 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) TPR_11 PF13414.1 CDI76093.1 - 1.3e-11 44.0 1.0 2.7e-07 30.1 0.5 2.9 2 0 0 2 2 2 2 TPR repeat TPR_19 PF14559.1 CDI76093.1 - 1.2e-08 35.1 2.4 3.4e-08 33.6 1.7 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.12 CDI76093.1 - 3.1e-08 32.9 0.8 0.011 15.6 0.0 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 CDI76093.1 - 9.1e-08 31.3 0.4 0.0014 18.1 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.1 CDI76093.1 - 9.5e-08 32.5 0.4 9.5e-08 32.5 0.3 3.7 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_9 PF13371.1 CDI76093.1 - 2.2e-07 30.5 9.4 2.3e-07 30.5 0.8 3.5 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 CDI76093.1 - 1.3e-05 25.3 1.2 1.3e-05 25.3 0.8 4.7 4 1 1 5 5 3 2 Tetratricopeptide repeat TPR_6 PF13174.1 CDI76093.1 - 1.4e-05 25.2 2.0 0.0005 20.3 0.2 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 CDI76093.1 - 5.8e-05 22.9 0.6 0.0002 21.2 0.4 1.9 1 0 0 1 1 1 1 Tetratricopeptide repeat Apc3 PF12895.2 CDI76093.1 - 0.00015 21.8 2.5 0.00052 20.0 0.3 2.5 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.1 CDI76093.1 - 0.00053 19.9 0.2 0.0022 18.0 0.2 2.2 1 0 0 1 1 1 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 CDI76093.1 - 0.009 15.8 0.4 3 7.7 0.0 2.8 1 1 1 2 2 2 1 Fis1 C-terminal tetratricopeptide repeat TPR_8 PF13181.1 CDI76093.1 - 0.011 15.5 0.2 0.11 12.2 0.0 2.4 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_4 PF07721.9 CDI76093.1 - 0.018 15.4 0.5 0.018 15.4 0.3 4.2 4 0 0 4 4 2 0 Tetratricopeptide repeat bZIP_Maf PF03131.12 CDI76093.1 - 0.062 13.6 6.1 1.1 9.5 1.0 2.9 2 0 0 2 2 2 0 bZIP Maf transcription factor Pex19 PF04614.7 CDI76093.1 - 0.1 12.2 4.6 0.11 12.1 2.1 1.7 1 1 0 1 1 1 0 Pex19 protein family Na_trans_assoc PF06512.8 CDI76093.1 - 0.13 12.1 0.1 0.13 12.1 0.1 2.6 3 0 0 3 3 3 0 Sodium ion transport-associated ORC5_C PF14630.1 CDI76094.1 - 0.11 11.8 0.0 0.18 11.2 0.0 1.2 1 0 0 1 1 1 0 Origin recognition complex (ORC) subunit 5 C-terminus IQ PF00612.22 CDI76096.1 - 0.007 15.9 0.2 0.015 14.9 0.1 1.6 1 0 0 1 1 1 1 IQ calmodulin-binding motif Med19 PF10278.4 CDI76110.1 - 0.0012 18.5 1.2 0.0018 17.9 0.9 1.3 1 0 0 1 1 1 1 Mediator of RNA pol II transcription subunit 19 PAT1 PF09770.4 CDI76110.1 - 0.0053 15.0 21.4 0.0046 15.2 14.9 1.1 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 FimP PF09766.4 CDI76110.1 - 0.11 11.4 15.7 0.14 11.2 10.9 1.2 1 0 0 1 1 1 0 Fms-interacting protein Ribosomal_60s PF00428.14 CDI76110.1 - 0.33 11.3 20.8 0.35 11.3 5.2 2.3 2 0 0 2 2 2 0 60s Acidic ribosomal protein Glt_symporter PF03616.9 CDI76110.1 - 0.82 8.0 3.4 0.63 8.4 1.7 1.3 1 1 0 1 1 1 0 Sodium/glutamate symporter DUF605 PF04652.11 CDI76110.1 - 1.2 8.4 22.2 1.5 8.1 15.4 1.1 1 0 0 1 1 1 0 Vta1 like SR-25 PF10500.4 CDI76110.1 - 2.4 7.5 25.0 1.2 8.5 6.7 2.3 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein EIIBC-GUT_N PF03612.9 CDI76110.1 - 4.6 6.8 6.8 7.8 6.0 4.7 1.4 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Ribosomal_60s PF00428.14 CDI76111.1 - 0.00012 22.4 39.4 0.13 12.6 4.3 3.2 3 0 0 3 3 3 3 60s Acidic ribosomal protein DUF775 PF05603.7 CDI76111.1 - 0.14 11.6 3.9 0.19 11.2 2.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF775) APC_CDC26 PF10471.4 CDI76111.1 - 0.44 11.3 8.5 0.82 10.4 5.9 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex APC subunit 1 PHD_3 PF13922.1 CDI76111.1 - 1.1 9.5 7.3 2.9 8.1 5.1 1.7 1 0 0 1 1 1 0 PHD domain of transcriptional enhancer, Asx TFIIA PF03153.8 CDI76111.1 - 2.1 8.1 10.4 2.8 7.7 7.2 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit UPF0565 PF10561.4 CDI76111.1 - 2.4 6.9 7.6 1.2 7.9 3.6 1.6 1 1 0 2 2 2 0 Uncharacterised protein family UPF0565 Tetraspannin PF00335.15 CDI76111.1 - 6.5 5.9 9.0 7.7 5.7 5.2 1.7 2 0 0 2 2 2 0 Tetraspanin family Glyco_trans_4_4 PF13579.1 CDI76112.1 - 0.0043 17.2 4.2 0.0057 16.8 2.9 1.2 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain DUF4640 PF15480.1 CDI76112.1 - 0.0045 16.6 2.9 0.0059 16.2 2.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4640) 2_5_RNA_ligase2 PF13563.1 CDI76112.1 - 0.029 14.0 2.5 0.032 13.9 1.2 1.5 1 1 0 1 1 1 0 2'-5' RNA ligase superfamily DUF506 PF04720.7 CDI76112.1 - 0.05 13.2 0.5 0.069 12.7 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF506) Cwf_Cwc_15 PF04889.7 CDI76112.1 - 0.69 9.5 5.7 0.061 13.0 1.0 1.5 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein POX PF07526.6 CDI76112.1 - 1 9.5 9.9 4.6 7.4 3.9 2.3 1 1 1 2 2 2 0 Associated with HOX DUF1635 PF07795.6 CDI76112.1 - 1.2 8.4 8.0 0.24 10.7 3.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1635) BSP_II PF05432.6 CDI76112.1 - 1.3 8.2 10.8 0.083 12.1 3.7 1.6 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) Med3 PF11593.3 CDI76112.1 - 2.1 7.4 10.9 2.9 7.0 7.6 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Herpes_capsid PF06112.6 CDI76112.1 - 9.2 6.2 16.0 8.8 6.3 3.6 2.3 2 0 0 2 2 2 0 Gammaherpesvirus capsid protein Raftlin PF15250.1 CDI76115.1 - 0.19 10.1 17.9 0.25 9.8 12.4 1.0 1 0 0 1 1 1 0 Raftlin Rtf2 PF04641.7 CDI76115.1 - 0.36 9.9 12.1 0.44 9.7 8.4 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger RR_TM4-6 PF06459.7 CDI76115.1 - 0.55 10.0 16.9 0.6 9.9 11.7 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Maf1 PF09174.5 CDI76115.1 - 0.6 9.9 8.4 0.78 9.5 5.8 1.2 1 0 0 1 1 1 0 Maf1 regulator Lipoprotein_X PF03305.8 CDI76115.1 - 0.72 9.1 12.4 0.8 9.0 8.6 1.1 1 0 0 1 1 1 0 Mycoplasma MG185/MG260 protein POP1 PF06978.6 CDI76115.1 - 0.95 9.0 16.2 1.3 8.6 11.2 1.2 1 0 0 1 1 1 0 Ribonucleases P/MRP protein subunit POP1 DUF4175 PF13779.1 CDI76115.1 - 0.95 7.0 49.3 1.1 6.9 34.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Lipoprotein_2 PF00921.12 CDI76115.1 - 1.1 9.2 3.5 1.5 8.8 2.5 1.2 1 0 0 1 1 1 0 Borrelia lipoprotein DDRGK PF09756.4 CDI76115.1 - 1.3 8.4 25.1 1.5 8.2 17.4 1.1 1 0 0 1 1 1 0 DDRGK domain DUF2407 PF10302.4 CDI76115.1 - 1.4 9.1 7.7 1.8 8.8 5.3 1.2 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain DUF2126 PF09899.4 CDI76115.1 - 1.6 6.7 13.1 1.7 6.5 9.1 1.1 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) UPF0233 PF06781.7 CDI76115.1 - 1.7 8.2 8.8 1.2 8.8 0.6 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0233) DUF605 PF04652.11 CDI76115.1 - 2 7.6 23.7 2.1 7.6 16.4 1.0 1 0 0 1 1 1 0 Vta1 like SpoIIP PF07454.6 CDI76115.1 - 2.5 7.2 12.9 3.2 6.8 8.9 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Bud13 PF09736.4 CDI76115.1 - 3.2 7.9 23.0 5.2 7.3 15.9 1.4 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex DUF2246 PF10229.4 CDI76115.1 - 3.3 6.9 11.9 3.7 6.7 8.2 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2246) DUF4045 PF13254.1 CDI76115.1 - 3.5 6.8 14.4 3.8 6.6 10.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) DUF45 PF01863.12 CDI76115.1 - 4.2 7.1 13.3 5.3 6.7 9.2 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF45 BNR_3 PF13859.1 CDI76115.1 - 4.5 6.2 6.1 5.7 5.9 4.3 1.2 1 0 0 1 1 1 0 BNR repeat-like domain DHHW PF14286.1 CDI76115.1 - 4.5 6.4 12.0 5.1 6.3 8.3 1.1 1 0 0 1 1 1 0 DHHW protein AUX_IAA PF02309.11 CDI76115.1 - 4.6 6.9 13.4 5.6 6.6 9.3 1.2 1 0 0 1 1 1 0 AUX/IAA family SPX PF03105.14 CDI76115.1 - 4.7 6.9 15.3 5.5 6.6 10.6 1.1 1 0 0 1 1 1 0 SPX domain HCO3_cotransp PF00955.16 CDI76115.1 - 5 5.6 6.7 5.7 5.4 4.7 1.0 1 0 0 1 1 1 0 HCO3- transporter family Trypan_glycop_C PF10659.4 CDI76115.1 - 5.7 7.3 13.9 1.8 8.8 2.5 2.1 2 0 0 2 2 2 0 Trypanosome variant surface glycoprotein C-terminal domain FLO_LFY PF01698.11 CDI76115.1 - 6.4 5.5 15.8 6.8 5.4 11.0 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein Mem_trans PF03547.13 CDI76115.1 - 6.6 4.9 8.7 7.4 4.7 6.0 1.1 1 0 0 1 1 1 0 Membrane transport protein eIF-3_zeta PF05091.7 CDI76115.1 - 7.2 5.1 23.9 7.5 5.0 16.6 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF1675 PF07897.6 CDI76115.1 - 7.8 6.2 10.6 8.4 6.1 7.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) Phycobilisome PF00502.14 CDI76115.1 - 8 6.1 8.0 21 4.8 5.5 1.6 1 1 0 1 1 1 0 Phycobilisome protein Baculo_PP31 PF05311.6 CDI76115.1 - 8.1 5.6 16.6 11 5.1 11.5 1.3 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) BTV_NS2 PF04514.7 CDI76115.1 - 8.6 5.1 15.1 9.1 5.0 10.5 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 SAPS PF04499.10 CDI76119.1 - 1.2e-05 24.1 8.8 0.29 9.7 0.0 3.2 2 1 0 2 2 2 1 SIT4 phosphatase-associated protein Activator_LAG-3 PF11498.3 CDI76119.1 - 0.00015 20.6 31.8 0.00015 20.6 22.0 2.4 2 0 0 2 2 2 1 Transcriptional activator LAG-3 UPF0564 PF10595.4 CDI76135.1 - 0.13 11.1 36.3 0.14 11.0 25.1 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0564 GAGA_bind PF06217.7 CDI76135.1 - 1.5 8.7 23.5 1.5 8.7 16.3 1.0 1 0 0 1 1 1 0 GAGA binding protein-like family DUF1510 PF07423.6 CDI76135.1 - 2 7.7 21.2 2.7 7.3 14.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Peptidase_S64 PF08192.6 CDI76135.1 - 2 6.6 14.5 2.2 6.4 10.1 1.0 1 0 0 1 1 1 0 Peptidase family S64 PAT1 PF09770.4 CDI76135.1 - 2.1 6.4 62.4 2.3 6.3 43.2 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 BTV_NS2 PF04514.7 CDI76135.1 - 2.5 6.8 17.5 3.2 6.5 12.1 1.2 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 DDHD PF02862.12 CDI76135.1 - 3.1 7.5 17.1 4.7 6.9 11.8 1.3 1 0 0 1 1 1 0 DDHD domain Hid1 PF12722.2 CDI76135.1 - 3.5 5.2 21.6 3.7 5.1 15.0 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Ycf1 PF05758.7 CDI76135.1 - 3.8 5.1 20.8 4.2 4.9 14.4 1.0 1 0 0 1 1 1 0 Ycf1 eIF-3_zeta PF05091.7 CDI76135.1 - 3.9 5.9 26.3 4.7 5.7 18.2 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Pox_Ag35 PF03286.9 CDI76135.1 - 4.2 6.8 13.9 5.7 6.4 9.6 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein PCEMA1 PF07418.6 CDI76135.1 - 4.4 6.5 11.0 4.8 6.4 7.6 1.2 1 0 0 1 1 1 0 Acidic phosphoprotein precursor PCEMA1 Lipoprotein_X PF03305.8 CDI76135.1 - 4.8 6.4 15.9 6.9 5.9 11.1 1.2 1 0 0 1 1 1 0 Mycoplasma MG185/MG260 protein FAM60A PF15396.1 CDI76135.1 - 5.8 6.5 21.2 6.9 6.3 14.7 1.1 1 0 0 1 1 1 0 Protein Family FAM60A Herpes_UL87 PF03043.9 CDI76135.1 - 7.7 4.7 14.1 7.8 4.7 9.8 1.0 1 0 0 1 1 1 0 Herpesvirus UL87 family TFIIA PF03153.8 CDI76135.1 - 8.2 6.2 39.6 9.2 6.0 27.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit ETRAMP PF09716.5 CDI76137.1 - 0.69 9.8 0.0 0.69 9.8 0.0 3.9 3 1 0 3 3 3 0 Malarial early transcribed membrane protein (ETRAMP) Secretin_N_2 PF07655.8 CDI76137.1 - 2.9 8.3 17.6 6.4 7.2 12.2 1.5 1 0 0 1 1 1 0 Secretin N-terminal domain DUF1645 PF07816.6 CDI76137.1 - 7.5 6.9 25.7 0.19 12.1 9.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1645) EPL1 PF10513.4 CDI76155.1 - 0.019 15.2 10.6 0.019 15.1 7.3 1.0 1 0 0 1 1 1 0 Enhancer of polycomb-like Med19 PF10278.4 CDI76155.1 - 0.024 14.3 5.0 0.029 14.0 3.5 1.1 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 FimP PF09766.4 CDI76155.1 - 0.025 13.6 19.1 0.027 13.5 13.2 1.1 1 0 0 1 1 1 0 Fms-interacting protein MT-A70 PF05063.9 CDI76155.1 - 0.026 14.1 2.3 0.04 13.4 0.0 2.0 2 0 0 2 2 2 0 MT-A70 PAT1 PF09770.4 CDI76155.1 - 0.046 11.9 24.2 0.047 11.9 16.8 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SAE2 PF08573.5 CDI76155.1 - 0.067 13.9 2.9 0.076 13.7 2.0 1.2 1 0 0 1 1 1 0 DNA repair protein endonuclease SAE2/CtIP C-terminus Suf PF05843.9 CDI76155.1 - 0.1 12.3 13.2 0.1 12.2 9.2 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) HCV_NS5a_C PF12941.2 CDI76155.1 - 0.1 12.1 5.1 0.12 11.9 3.5 1.1 1 0 0 1 1 1 0 HCV NS5a protein C-terminal region UPF0560 PF10577.4 CDI76155.1 - 0.13 10.5 18.1 0.15 10.3 12.6 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 OATP PF03137.15 CDI76155.1 - 0.14 10.2 4.6 0.14 10.1 3.2 1.0 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family AUX_IAA PF02309.11 CDI76155.1 - 0.16 11.6 6.1 0.16 11.6 4.2 1.1 1 0 0 1 1 1 0 AUX/IAA family LIM_bind PF01803.11 CDI76155.1 - 0.17 11.0 8.1 0.15 11.1 5.6 1.1 1 0 0 1 1 1 0 LIM-domain binding protein AIF_C PF14721.1 CDI76155.1 - 0.24 11.6 6.0 0.26 11.5 4.2 1.1 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term FAM60A PF15396.1 CDI76155.1 - 0.27 10.9 4.2 0.28 10.8 2.9 1.1 1 0 0 1 1 1 0 Protein Family FAM60A TFIIA PF03153.8 CDI76155.1 - 0.37 10.6 19.9 0.38 10.6 13.8 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Endonuc_Holl PF10107.4 CDI76155.1 - 0.38 10.4 7.5 0.4 10.3 5.2 1.1 1 0 0 1 1 1 0 Endonuclease related to archaeal Holliday junction resolvase Band_3_cyto PF07565.8 CDI76155.1 - 0.38 10.2 8.4 0.39 10.1 5.8 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain RIC3 PF15361.1 CDI76155.1 - 0.39 10.9 11.1 0.46 10.7 7.7 1.1 1 0 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 DUF3449 PF11931.3 CDI76155.1 - 0.51 9.8 10.1 0.59 9.6 7.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3449) zf-DHHC PF01529.15 CDI76155.1 - 0.52 9.6 3.9 0.53 9.6 2.7 1.1 1 0 0 1 1 1 0 DHHC palmitoyltransferase CagX PF03524.10 CDI76155.1 - 0.53 9.5 7.6 0.59 9.3 5.3 1.2 1 0 0 1 1 1 0 Conjugal transfer protein CDC45 PF02724.9 CDI76155.1 - 0.54 8.2 8.0 0.57 8.1 5.6 1.0 1 0 0 1 1 1 0 CDC45-like protein Peptidase_S49_N PF08496.5 CDI76155.1 - 0.55 10.0 9.1 0.63 9.8 6.3 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Baculo_PP31 PF05311.6 CDI76155.1 - 0.59 9.3 7.6 0.61 9.2 5.3 1.1 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) Pal1 PF08316.6 CDI76155.1 - 0.66 10.4 3.5 0.75 10.2 2.4 1.1 1 0 0 1 1 1 0 Pal1 cell morphology protein Gag_spuma PF03276.9 CDI76155.1 - 0.78 7.9 22.1 0.79 7.9 15.3 1.0 1 0 0 1 1 1 0 Spumavirus gag protein FLO_LFY PF01698.11 CDI76155.1 - 0.79 8.5 9.6 0.86 8.3 6.7 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein eIF-3_zeta PF05091.7 CDI76155.1 - 0.79 8.2 13.3 0.84 8.1 9.2 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Hid1 PF12722.2 CDI76155.1 - 0.82 7.2 9.9 0.81 7.2 6.9 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein PIH1 PF08190.7 CDI76155.1 - 0.85 9.0 13.4 0.9 8.9 9.3 1.0 1 0 0 1 1 1 0 pre-RNA processing PIH1/Nop17 DUF2201_N PF13203.1 CDI76155.1 - 0.91 8.6 11.9 0.97 8.5 8.3 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain Paf1 PF03985.8 CDI76155.1 - 0.93 8.1 14.9 0.98 8.0 10.3 1.1 1 0 0 1 1 1 0 Paf1 NARP1 PF12569.3 CDI76155.1 - 1.1 7.9 11.4 1.1 7.8 7.9 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DUF4407 PF14362.1 CDI76155.1 - 1.3 7.9 13.1 1.2 7.9 9.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Med15 PF09606.5 CDI76155.1 - 1.4 7.0 39.4 1.5 6.9 27.3 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Gti1_Pac2 PF09729.4 CDI76155.1 - 1.4 8.7 6.7 1.6 8.5 4.7 1.1 1 0 0 1 1 1 0 Gti1/Pac2 family DHHW PF14286.1 CDI76155.1 - 1.5 8.1 6.4 1.5 8.0 4.5 1.0 1 0 0 1 1 1 0 DHHW protein MDFI PF15316.1 CDI76155.1 - 1.5 8.8 5.1 1.7 8.6 3.5 1.1 1 0 0 1 1 1 0 MyoD family inhibitor Spore_coat_CotO PF14153.1 CDI76155.1 - 1.5 8.2 16.5 1.6 8.1 11.4 1.1 1 0 0 1 1 1 0 Spore coat protein CotO SprA-related PF12118.3 CDI76155.1 - 1.7 7.9 27.4 1.8 7.8 19.0 1.1 1 0 0 1 1 1 0 SprA-related family DDHD PF02862.12 CDI76155.1 - 1.8 8.3 10.0 1.9 8.2 6.9 1.1 1 0 0 1 1 1 0 DDHD domain DUF1764 PF08576.5 CDI76155.1 - 1.9 9.3 13.4 2.4 8.9 9.3 1.1 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) EIIBC-GUT_N PF03612.9 CDI76155.1 - 1.9 8.0 7.2 2 7.9 5.0 1.2 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus RR_TM4-6 PF06459.7 CDI76155.1 - 2 8.2 11.2 2.2 8.1 7.8 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Pex14_N PF04695.8 CDI76155.1 - 2.5 8.1 16.2 3 7.9 11.2 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Neur_chan_memb PF02932.11 CDI76155.1 - 2.6 7.8 5.1 2.6 7.8 3.5 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region CRF1 PF10380.4 CDI76155.1 - 2.7 8.3 7.2 3.2 8.1 5.0 1.2 1 0 0 1 1 1 0 Transcription factor CRF1 Serinc PF03348.10 CDI76155.1 - 3 6.4 10.2 3.1 6.3 7.1 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) DUF4446 PF14584.1 CDI76155.1 - 3.1 7.6 8.6 3.8 7.3 6.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) Paramyxo_ncap PF00973.14 CDI76155.1 - 3.2 6.3 6.5 3.1 6.3 4.5 1.0 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein DUF4175 PF13779.1 CDI76155.1 - 3.2 5.3 36.3 3.7 5.1 25.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) BRF1 PF07741.8 CDI76155.1 - 3.3 7.9 13.2 4.2 7.6 9.2 1.2 1 0 0 1 1 1 0 Brf1-like TBP-binding domain DUF912 PF06024.7 CDI76155.1 - 3.5 7.7 7.5 4.5 7.3 5.2 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Ctr PF04145.10 CDI76155.1 - 3.5 7.6 7.3 4.6 7.2 5.1 1.1 1 0 0 1 1 1 0 Ctr copper transporter family EFF-AFF PF14884.1 CDI76155.1 - 3.7 5.4 9.4 4.2 5.3 6.5 1.0 1 0 0 1 1 1 0 Type I membrane glycoproteins cell-cell fusogen Borrelia_P83 PF05262.6 CDI76155.1 - 3.8 5.6 14.9 4.1 5.5 10.4 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein FAM176 PF14851.1 CDI76155.1 - 3.9 7.1 6.5 4.9 6.8 4.5 1.2 1 0 0 1 1 1 0 FAM176 family V_ATPase_I PF01496.14 CDI76155.1 - 4.2 5.1 7.0 4.8 4.9 4.8 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Peptidase_U57 PF05582.7 CDI76155.1 - 4.4 6.1 7.7 4.7 6.0 5.4 1.0 1 0 0 1 1 1 0 YabG peptidase U57 CobT PF06213.7 CDI76155.1 - 4.5 6.3 11.9 5.2 6.1 8.2 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF2215 PF10225.4 CDI76155.1 - 4.6 6.6 6.3 4.6 6.6 4.4 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) AAA_23 PF13476.1 CDI76155.1 - 4.7 7.4 21.1 5.5 7.2 14.6 1.0 1 0 0 1 1 1 0 AAA domain Pex16 PF08610.5 CDI76155.1 - 4.9 6.0 12.2 5.6 5.8 8.5 1.1 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) ATAD4 PF15321.1 CDI76155.1 - 4.9 8.2 10.2 7 7.7 7.0 1.4 1 0 0 1 1 1 0 ATPase family AAA domain containing 4 Plasmodium_Vir PF05795.6 CDI76155.1 - 5 6.2 5.6 5.4 6.1 3.9 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Pex26 PF07163.7 CDI76155.1 - 5.1 5.9 13.8 6.1 5.6 9.6 1.1 1 0 0 1 1 1 0 Pex26 protein DUF4557 PF15101.1 CDI76155.1 - 5.7 6.7 22.9 6.8 6.4 15.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) Peroxin-13_N PF04088.8 CDI76155.1 - 5.8 6.8 6.7 8.1 6.3 4.6 1.3 1 0 0 1 1 1 0 Peroxin 13, N-terminal region FCP1_C PF09309.5 CDI76155.1 - 6.4 6.0 16.4 7.7 5.7 11.4 1.1 1 0 0 1 1 1 0 FCP1, C-terminal APG6 PF04111.7 CDI76155.1 - 8 5.4 15.3 8.2 5.3 10.6 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF3043 PF11241.3 CDI76155.1 - 9.5 5.7 10.4 12 5.4 7.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) Ycf1 PF05758.7 CDI76155.1 - 9.8 3.7 11.5 10 3.7 8.0 1.0 1 0 0 1 1 1 0 Ycf1 Bromodomain PF00439.20 CDI76164.1 - 2.1e-19 69.2 0.0 3.2e-19 68.6 0.0 1.3 1 0 0 1 1 1 1 Bromodomain Ribosomal_60s PF00428.14 CDI76164.1 - 0.47 10.8 6.0 0.88 10.0 4.2 1.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein Acetyltransf_7 PF13508.1 CDI76167.1 - 4.3e-08 33.2 0.0 8e-08 32.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 CDI76167.1 - 6.5e-08 32.4 0.0 1.2e-07 31.5 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 CDI76167.1 - 0.0028 17.7 0.0 0.018 15.1 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 CDI76167.1 - 0.02 15.0 0.0 0.045 13.9 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Flg_hook PF02120.11 CDI76168.1 - 0.035 13.7 1.0 0.19 11.4 0.1 2.7 2 1 1 3 3 3 0 Flagellar hook-length control protein FliK Glycoprotein_B PF00606.13 CDI76168.1 - 0.13 10.2 0.2 0.18 9.7 0.2 1.1 1 0 0 1 1 1 0 Herpesvirus Glycoprotein B RNA_binding PF01877.12 CDI76168.1 - 0.39 10.7 3.7 0.87 9.6 2.6 1.5 1 0 0 1 1 1 0 RNA binding APG6 PF04111.7 CDI76169.1 - 0.0019 17.3 4.2 0.0019 17.3 2.9 1.7 2 0 0 2 2 2 1 Autophagy protein Apg6 Tropomyosin_1 PF12718.2 CDI76169.1 - 0.0023 17.7 7.7 0.0023 17.7 5.3 2.0 2 0 0 2 2 2 1 Tropomyosin like PAH PF02671.16 CDI76169.1 - 0.018 14.6 2.0 0.02 14.4 0.2 1.9 2 0 0 2 2 2 0 Paired amphipathic helix repeat Macoilin PF09726.4 CDI76169.1 - 0.021 13.1 3.2 0.037 12.3 2.2 1.4 1 0 0 1 1 1 0 Transmembrane protein Mnd1 PF03962.10 CDI76169.1 - 0.054 13.1 9.4 0.019 14.6 4.2 1.7 2 0 0 2 2 2 0 Mnd1 family V_ATPase_I PF01496.14 CDI76169.1 - 0.072 10.9 1.7 0.081 10.7 1.2 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Phlebovirus_NSM PF07246.6 CDI76169.1 - 0.08 12.0 3.7 0.13 11.4 2.6 1.2 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M TMF_TATA_bd PF12325.3 CDI76169.1 - 0.084 12.6 12.1 0.18 11.5 6.3 2.1 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF2353 PF09789.4 CDI76169.1 - 0.1 11.8 8.6 0.051 12.8 3.9 1.7 2 0 0 2 2 2 0 Uncharacterized coiled-coil protein (DUF2353) Laminin_I PF06008.9 CDI76169.1 - 0.11 11.7 11.1 1.4 8.1 4.7 2.1 2 0 0 2 2 2 0 Laminin Domain I TMF_DNA_bd PF12329.3 CDI76169.1 - 0.16 11.7 15.9 0.38 10.5 6.6 2.9 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding ATG16 PF08614.6 CDI76169.1 - 0.18 11.6 13.8 0.054 13.3 4.5 2.7 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) GAS PF13851.1 CDI76169.1 - 0.24 10.5 10.1 0.13 11.4 4.3 2.1 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Phage_GP20 PF06810.6 CDI76169.1 - 0.24 10.8 11.3 0.25 10.7 5.6 2.3 2 1 0 2 2 2 0 Phage minor structural protein GP20 ADIP PF11559.3 CDI76169.1 - 0.79 9.6 15.6 0.4 10.5 8.0 2.2 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding DUF948 PF06103.6 CDI76169.1 - 2.9 7.7 6.2 5.9 6.8 1.6 2.6 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) Spc7 PF08317.6 CDI76169.1 - 3.3 6.2 12.3 3.2 6.3 6.4 2.1 2 1 0 2 2 2 0 Spc7 kinetochore protein CENP-Q PF13094.1 CDI76169.1 - 4.9 7.1 13.6 1.5 8.8 6.7 2.0 2 1 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF972 PF06156.8 CDI76169.1 - 6 7.2 9.4 3 8.2 3.8 2.2 2 1 1 3 3 3 0 Protein of unknown function (DUF972) COG2 PF06148.6 CDI76169.1 - 6.7 6.5 8.2 2.6 7.8 3.9 1.5 2 0 0 2 2 1 0 COG (conserved oligomeric Golgi) complex component, COG2 FUSC PF04632.7 CDI76169.1 - 7.3 4.8 7.8 3.1 6.1 3.6 1.5 1 1 0 1 1 1 0 Fusaric acid resistance protein family DUF4140 PF13600.1 CDI76169.1 - 7.8 7.0 10.9 15 6.1 0.3 3.0 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) Atg14 PF10186.4 CDI76169.1 - 9.4 5.0 11.7 3.7 6.4 6.5 1.4 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 MMR_HSR1 PF01926.18 CDI76170.1 - 3.8e-18 65.5 0.1 2.6e-15 56.3 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.13 CDI76170.1 - 9.7e-06 24.9 0.0 4.2e-05 22.8 0.0 1.9 2 0 0 2 2 2 1 Ferrous iron transport protein B DUF258 PF03193.11 CDI76170.1 - 0.00072 18.7 0.1 0.0017 17.6 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Dynamin_N PF00350.18 CDI76170.1 - 0.021 14.6 1.1 0.18 11.6 0.1 2.8 2 1 1 3 3 3 0 Dynamin family Miro PF08477.8 CDI76170.1 - 0.022 15.2 0.0 0.068 13.6 0.0 1.8 1 0 0 1 1 1 0 Miro-like protein zf-CDGSH PF09360.5 CDI76171.1 - 7.2e-08 32.1 0.6 7.2e-08 32.1 0.4 2.1 3 0 0 3 3 3 1 Iron-binding zinc finger CDGSH type BT1 PF03092.11 CDI76174.1 - 9.2e-41 139.9 7.9 2.2e-40 138.6 5.5 1.5 1 1 0 1 1 1 1 BT1 family Mt_ATP-synt_B PF05405.9 CDI76174.1 - 0.028 13.8 1.4 0.12 11.7 1.2 1.9 2 0 0 2 2 2 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) Prominin PF05478.6 CDI76174.1 - 0.47 7.9 1.6 0.78 7.2 1.1 1.2 1 0 0 1 1 1 0 Prominin STT3 PF02516.9 CDI76175.1 - 8.3e-48 163.5 35.6 8.3e-48 163.5 24.6 1.6 1 1 0 2 2 2 1 Oligosaccharyl transferase STT3 subunit DUF859 PF05895.7 CDI76175.1 - 0.12 10.6 0.0 0.17 10.1 0.0 1.1 1 0 0 1 1 1 0 Siphovirus protein of unknown function (DUF859) Foie-gras_1 PF11817.3 CDI76176.1 - 1.1e-10 41.3 0.4 3.3e-10 39.8 0.3 1.8 1 1 0 1 1 1 1 Foie gras liver health family 1 Gryzun PF07919.7 CDI76176.1 - 0.00032 19.1 0.0 0.00046 18.6 0.0 1.2 1 0 0 1 1 1 1 Gryzun, putative trafficking through Golgi MHC_I_C PF06623.6 CDI76176.1 - 0.044 13.2 0.1 0.094 12.2 0.1 1.6 1 0 0 1 1 1 0 MHC_I C-terminus WD40 PF00400.27 CDI76177.1 - 2.6e-06 27.0 6.5 0.00019 21.1 0.2 4.7 5 0 0 5 5 5 2 WD domain, G-beta repeat FUSC_2 PF13515.1 CDI76179.1 - 3e-13 49.8 11.6 3e-13 49.8 8.0 3.1 3 1 0 3 3 3 1 Fusaric acid resistance protein-like Peptidase_C2 PF00648.16 CDI76179.1 - 0.048 12.6 0.0 0.091 11.7 0.0 1.4 1 0 0 1 1 1 0 Calpain family cysteine protease MMtag PF10159.4 CDI76180.1 - 1.9e-16 59.8 4.7 1.9e-16 59.8 3.3 4.4 4 2 0 4 4 4 1 Kinase phosphorylation protein E1-E2_ATPase PF00122.15 CDI76183.1 - 4.7e-54 182.8 0.0 4.7e-54 182.8 0.0 2.5 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 CDI76183.1 - 2.9e-29 101.9 0.1 2.9e-29 101.9 0.1 4.2 5 0 0 5 5 5 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 CDI76183.1 - 1.7e-23 84.1 0.0 1.4e-22 81.1 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 CDI76183.1 - 6.1e-14 51.7 0.1 1.3e-13 50.6 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 CDI76183.1 - 3.4e-13 50.1 0.0 1.2e-12 48.4 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 CDI76183.1 - 9.5e-09 34.5 0.0 3e-08 32.9 0.0 1.9 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 CDI76183.1 - 0.00013 21.6 0.5 0.0014 18.2 0.2 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase YABBY PF04690.8 CDI76183.1 - 0.06 13.5 0.0 0.14 12.3 0.0 1.6 1 0 0 1 1 1 0 YABBY protein AMP-binding PF00501.23 CDI76184.1 - 2.1e-84 283.3 0.0 1.1e-83 280.9 0.0 1.8 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 CDI76184.1 - 2.3e-16 60.4 1.2 6e-16 59.1 0.8 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Pex14_N PF04695.8 CDI76191.1 - 0.0033 17.4 30.9 0.0079 16.2 7.7 8.5 3 1 3 6 6 6 2 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF2052 PF09747.4 CDI76191.1 - 0.011 15.6 8.0 0.011 15.6 5.5 6.2 3 1 2 5 5 5 0 Coiled-coil domain containing protein (DUF2052) Cpn60_TCP1 PF00118.19 CDI76192.1 - 1.9e-98 330.2 4.1 3.6e-56 190.7 0.3 2.0 1 1 1 2 2 2 2 TCP-1/cpn60 chaperonin family HycA_repressor PF11046.3 CDI76192.1 - 0.068 13.1 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 Transcriptional repressor of hyc and hyp operons LUC7 PF03194.10 CDI76193.1 - 8.5e-41 140.1 2.6 1e-40 139.8 1.8 1.0 1 0 0 1 1 1 1 LUC7 N_terminus Occludin_ELL PF07303.8 CDI76193.1 - 0.00025 21.7 2.6 0.00042 21.0 1.8 1.3 1 0 0 1 1 1 1 Occludin homology domain HSCB_C PF07743.8 CDI76193.1 - 0.011 16.2 6.6 0.025 15.0 3.7 2.1 1 1 2 3 3 3 0 HSCB C-terminal oligomerisation domain Mnd1 PF03962.10 CDI76193.1 - 0.042 13.5 4.8 0.059 13.0 3.3 1.2 1 0 0 1 1 1 0 Mnd1 family V_ATPase_I PF01496.14 CDI76193.1 - 0.075 10.8 1.9 0.095 10.5 1.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family FCD PF07729.7 CDI76193.1 - 0.086 13.1 2.5 0.14 12.5 0.6 2.0 1 1 1 2 2 2 0 FCD domain NPV_P10 PF05531.7 CDI76193.1 - 0.12 12.6 5.2 3.8 7.8 0.1 2.3 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein HSBP1 PF06825.7 CDI76193.1 - 0.14 11.7 0.1 0.14 11.7 0.1 2.6 3 0 0 3 3 3 0 Heat shock factor binding protein 1 IncA PF04156.9 CDI76193.1 - 0.18 11.4 7.6 0.25 10.8 5.3 1.1 1 0 0 1 1 1 0 IncA protein ADIP PF11559.3 CDI76193.1 - 0.24 11.3 8.2 0.65 9.8 2.9 2.1 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding TnpV PF14198.1 CDI76193.1 - 0.24 11.2 1.9 0.47 10.3 1.3 1.4 1 0 0 1 1 1 0 Transposon-encoded protein TnpV DUF1192 PF06698.6 CDI76193.1 - 0.28 11.0 2.9 4 7.3 0.0 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1192) Syntaxin_2 PF14523.1 CDI76193.1 - 0.39 10.7 4.4 2 8.5 2.9 1.9 1 1 1 2 2 2 0 Syntaxin-like protein SlyX PF04102.7 CDI76193.1 - 0.46 10.8 5.9 15 6.0 0.0 2.8 1 1 0 2 2 2 0 SlyX DUF1090 PF06476.7 CDI76193.1 - 0.46 10.1 5.6 0.74 9.4 3.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1090) bZIP_Maf PF03131.12 CDI76193.1 - 0.78 10.0 5.2 1.3 9.3 1.4 2.3 1 1 1 2 2 2 0 bZIP Maf transcription factor bZIP_2 PF07716.10 CDI76193.1 - 0.82 9.5 13.4 6.2 6.7 1.4 3.3 3 0 0 3 3 3 0 Basic region leucine zipper DUF4164 PF13747.1 CDI76193.1 - 1 9.5 8.6 9.7 6.4 5.9 2.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4164) DUF972 PF06156.8 CDI76193.1 - 2.5 8.4 6.4 11 6.3 4.5 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF972) DivIC PF04977.10 CDI76193.1 - 5.6 6.5 8.3 15 5.1 0.1 2.7 1 1 1 3 3 3 0 Septum formation initiator DnaJ-X PF14308.1 CDI76194.1 - 1.6e-21 76.5 0.4 1.6e-21 76.5 0.3 2.4 2 0 0 2 2 2 1 X-domain of DnaJ-containing ATG_C PF09333.6 CDI76194.1 - 7.8e-05 22.7 0.0 0.00027 21.0 0.0 1.9 1 0 0 1 1 1 1 ATG C terminal domain SR-25 PF10500.4 CDI76194.1 - 0.01 15.3 16.4 0.01 15.3 11.4 3.1 3 0 0 3 3 3 0 Nuclear RNA-splicing-associated protein Med15 PF09606.5 CDI76194.1 - 0.034 12.3 39.6 0.055 11.6 11.6 2.2 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF1183 PF06682.7 CDI76194.1 - 0.45 10.0 28.1 0.042 13.4 1.5 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1183) Spt20 PF12090.3 CDI76194.1 - 0.91 8.8 16.6 0.46 9.8 1.5 2.3 2 0 0 2 2 2 0 Spt20 family OmpH PF03938.9 CDI76194.1 - 1.3 8.9 30.8 0.016 15.1 5.8 2.3 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) FNIP_N PF14636.1 CDI76194.1 - 1.9 8.9 28.7 0.3 11.5 1.2 3.3 3 0 0 3 3 3 0 Folliculin-interacting protein N-terminus Peptidase_U57 PF05582.7 CDI76194.1 - 9.7 5.0 9.8 0.85 8.5 0.4 2.2 2 0 0 2 2 2 0 YabG peptidase U57 A_amylase_inhib PF01356.14 CDI76207.1 - 0.0011 18.6 0.2 0.0025 17.5 0.1 1.5 1 0 0 1 1 1 1 Alpha amylase inhibitor CAF-1_p150 PF11600.3 CDI76207.1 - 0.0042 16.4 33.4 0.0042 16.4 23.1 3.6 3 1 0 3 3 3 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal Rib_5-P_isom_A PF06026.9 CDI76211.1 - 1.8e-42 144.6 0.1 1.7e-24 86.0 0.1 2.2 2 0 0 2 2 2 2 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) Ycf1 PF05758.7 CDI76214.1 - 6.5e-05 20.8 1.4 6.5e-05 20.8 1.0 1.0 1 0 0 1 1 1 1 Ycf1 Neur_chan_memb PF02932.11 CDI76214.1 - 0.0028 17.5 1.1 0.0028 17.5 0.8 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Spore_coat_CotO PF14153.1 CDI76214.1 - 0.018 14.5 18.3 0.025 14.0 12.7 1.2 1 0 0 1 1 1 0 Spore coat protein CotO vMSA PF00695.14 CDI76214.1 - 0.042 13.0 2.1 0.065 12.4 1.4 1.2 1 0 0 1 1 1 0 Major surface antigen from hepadnavirus PAT1 PF09770.4 CDI76214.1 - 0.05 11.8 35.1 0.073 11.3 24.3 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Pex14_N PF04695.8 CDI76214.1 - 0.099 12.6 20.2 0.066 13.2 12.2 2.0 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region CDK5_activator PF03261.10 CDI76214.1 - 0.2 10.9 12.4 0.088 12.1 6.6 1.7 2 0 0 2 2 2 0 Cyclin-dependent kinase 5 activator protein NARP1 PF12569.3 CDI76214.1 - 0.32 9.7 17.4 0.49 9.0 12.1 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 BORG_CEP PF14957.1 CDI76214.1 - 0.34 11.8 13.9 0.61 11.0 9.6 1.4 1 0 0 1 1 1 0 Cdc42 effector CDC45 PF02724.9 CDI76214.1 - 1.2 7.1 13.9 1.5 6.7 9.7 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF605 PF04652.11 CDI76214.1 - 1.4 8.2 23.3 2.5 7.4 16.2 1.3 1 0 0 1 1 1 0 Vta1 like UPF0560 PF10577.4 CDI76214.1 - 1.8 6.7 21.6 2.3 6.3 15.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Peptidase_U57 PF05582.7 CDI76214.1 - 1.9 7.4 8.7 2.7 6.8 6.0 1.2 1 0 0 1 1 1 0 YabG peptidase U57 AUX_IAA PF02309.11 CDI76214.1 - 2.3 7.8 12.6 3.7 7.2 8.7 1.2 1 0 0 1 1 1 0 AUX/IAA family RR_TM4-6 PF06459.7 CDI76214.1 - 3 7.6 18.1 4.6 7.0 12.5 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 V_ATPase_I PF01496.14 CDI76214.1 - 3.4 5.4 5.9 4.1 5.1 4.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4557 PF15101.1 CDI76214.1 - 3.6 7.3 26.8 7.5 6.3 18.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) FAM60A PF15396.1 CDI76214.1 - 3.6 7.2 14.0 5.4 6.7 9.7 1.2 1 0 0 1 1 1 0 Protein Family FAM60A TFIIA PF03153.8 CDI76214.1 - 3.9 7.2 32.7 0.1 12.4 17.4 1.8 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit YqfQ PF14181.1 CDI76214.1 - 5.2 7.0 24.9 3.5 7.6 11.7 2.3 2 0 0 2 2 2 0 YqfQ-like protein Dicty_REP PF05086.7 CDI76214.1 - 5.3 4.6 10.3 6.7 4.3 7.2 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein MMR1 PF08505.5 CDI76214.1 - 6.5 6.7 22.5 11 6.0 15.6 1.3 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein Gti1_Pac2 PF09729.4 CDI76214.1 - 8.8 6.1 10.6 15 5.4 7.4 1.4 1 0 0 1 1 1 0 Gti1/Pac2 family DDHD PF02862.12 CDI76214.1 - 9.3 5.9 17.8 15 5.2 12.4 1.3 1 0 0 1 1 1 0 DDHD domain FLO_LFY PF01698.11 CDI76214.1 - 9.4 4.9 19.3 15 4.3 13.4 1.2 1 0 0 1 1 1 0 Floricaula / Leafy protein PAT1 PF09770.4 CDI76216.1 - 0.0027 16.0 30.5 0.0024 16.1 21.2 1.2 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 SAGA-Tad1 PF12767.2 CDI76216.1 - 0.055 13.1 13.1 0.058 13.0 9.1 1.2 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit Ycf1 PF05758.7 CDI76216.1 - 0.06 11.0 9.9 0.053 11.2 6.8 1.0 1 0 0 1 1 1 0 Ycf1 MAT1 PF06391.8 CDI76216.1 - 0.17 11.4 19.1 0.19 11.2 13.2 1.1 1 0 0 1 1 1 0 CDK-activating kinase assembly factor MAT1 Band_3_cyto PF07565.8 CDI76216.1 - 0.34 10.4 10.8 0.36 10.2 7.5 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain TT_ORF1 PF02956.9 CDI76216.1 - 0.49 8.7 8.6 0.44 8.9 6.0 1.0 1 0 0 1 1 1 0 TT viral orf 1 YjgP_YjgQ PF03739.9 CDI76216.1 - 0.49 9.0 3.7 0.47 9.1 2.6 1.2 1 0 0 1 1 1 0 Predicted permease YjgP/YjgQ family Hid1 PF12722.2 CDI76216.1 - 0.56 7.8 11.2 0.5 7.9 7.8 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Maf1 PF09174.5 CDI76216.1 - 0.59 9.9 11.8 0.76 9.6 8.2 1.1 1 0 0 1 1 1 0 Maf1 regulator Utp14 PF04615.8 CDI76216.1 - 0.75 7.8 17.7 0.77 7.8 12.3 1.0 1 0 0 1 1 1 0 Utp14 protein DUF4220 PF13968.1 CDI76216.1 - 1.1 8.3 9.0 1.4 7.9 6.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4220) Afi1 PF07792.7 CDI76216.1 - 1.2 9.1 15.2 1.6 8.7 10.5 1.3 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking PBP1_TM PF14812.1 CDI76216.1 - 1.3 9.3 6.7 1.9 8.8 4.6 1.2 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF1632 PF07857.7 CDI76216.1 - 1.8 7.7 4.4 2.6 7.2 3.1 1.2 1 0 0 1 1 1 0 CEO family (DUF1632) LMBR1 PF04791.11 CDI76216.1 - 2 6.8 6.0 1.8 7.0 4.2 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein FAM60A PF15396.1 CDI76216.1 - 2.1 8.0 8.3 2.2 7.9 5.7 1.3 1 0 0 1 1 1 0 Protein Family FAM60A Neur_chan_memb PF02932.11 CDI76216.1 - 2.4 8.0 6.3 2.4 7.9 4.4 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF4045 PF13254.1 CDI76216.1 - 2.5 7.3 12.8 2.6 7.2 8.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) FemAB PF02388.11 CDI76216.1 - 2.5 6.6 17.0 2.5 6.6 11.8 1.2 1 0 0 1 1 1 0 FemAB family SecA_DEAD PF07517.9 CDI76216.1 - 2.6 7.2 10.5 2.6 7.2 7.3 1.2 1 0 0 1 1 1 0 SecA DEAD-like domain RHSP PF07999.6 CDI76216.1 - 2.7 6.4 6.2 3 6.3 4.3 1.1 1 0 0 1 1 1 0 Retrotransposon hot spot protein DUF913 PF06025.7 CDI76216.1 - 2.8 6.5 13.0 2 7.0 8.3 1.3 1 1 0 1 1 1 0 Domain of Unknown Function (DUF913) HGTP_anticodon2 PF12745.2 CDI76216.1 - 2.9 6.9 16.8 3.6 6.6 11.6 1.1 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs Plasmodium_Vir PF05795.6 CDI76216.1 - 3.4 6.7 4.6 4.3 6.4 3.2 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Phage_int_SAM_5 PF13102.1 CDI76216.1 - 3.9 7.4 12.9 5.2 7.0 9.0 1.2 1 0 0 1 1 1 0 Phage integrase SAM-like domain eIF-3_zeta PF05091.7 CDI76216.1 - 4.7 5.7 18.1 4.8 5.6 12.6 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) HlyD_2 PF12700.2 CDI76216.1 - 5.2 6.1 20.8 5.2 6.1 14.4 1.1 1 0 0 1 1 1 0 HlyD family secretion protein DUF4484 PF14831.1 CDI76216.1 - 5.5 7.0 9.8 6.7 6.7 6.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4484) PLRV_ORF5 PF01690.12 CDI76216.1 - 6.2 5.8 15.0 6.9 5.6 10.4 1.0 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Glyco_transf_15 PF01793.11 CDI76216.1 - 6.6 5.5 15.3 8.2 5.2 10.6 1.1 1 0 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase DUF2126 PF09899.4 CDI76216.1 - 7.3 4.4 10.2 7.2 4.5 7.0 1.2 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) Ric8 PF10165.4 CDI76216.1 - 7.6 5.2 13.9 8.7 5.0 9.6 1.1 1 0 0 1 1 1 0 Guanine nucleotide exchange factor synembryn V_ATPase_I PF01496.14 CDI76216.1 - 7.9 4.1 10.6 7.9 4.1 7.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF3492 PF11997.3 CDI76216.1 - 9 5.7 13.3 11 5.5 9.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3492) Cellulose_synt PF03552.9 CDI76216.1 - 9.8 4.3 7.1 10 4.2 4.9 1.1 1 0 0 1 1 1 0 Cellulose synthase Spt20 PF12090.3 CDI76232.1 - 0.0015 17.9 1.7 0.0015 17.9 1.2 2.1 1 1 1 2 2 2 1 Spt20 family DUF1637 PF07847.7 CDI76232.1 - 0.01 15.2 1.1 0.022 14.1 0.7 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1637) DUF1180 PF06679.7 CDI76232.1 - 0.23 11.3 4.1 7.4 6.4 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) TraT PF05818.7 CDI76232.1 - 0.4 10.0 9.4 0.23 10.8 1.1 2.1 2 0 0 2 2 2 0 Enterobacterial TraT complement resistance protein PHD_3 PF13922.1 CDI76232.1 - 1.6 9.0 11.4 0.88 9.8 2.4 2.5 2 0 0 2 2 2 0 PHD domain of transcriptional enhancer, Asx RAB3GAP2_N PF14655.1 CDI76232.1 - 2.8 6.8 13.7 0.35 9.8 4.1 2.1 1 1 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus G0-G1_switch_2 PF15103.1 CDI76232.1 - 3.2 8.0 6.7 19 5.5 0.3 2.3 2 0 0 2 2 2 0 G0/G1 switch protein 2 DUF1528 PF07515.6 CDI76232.1 - 5.3 7.1 9.8 0.21 11.6 2.8 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1528) DUF3530 PF12048.3 CDI76233.1 - 0.0014 17.7 15.6 0.0015 17.5 10.8 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3530) AIF_C PF14721.1 CDI76233.1 - 0.0019 18.4 12.9 0.0024 18.1 9.0 1.1 1 0 0 1 1 1 1 Apoptosis-inducing factor, mitochondrion-associated, C-term FAM176 PF14851.1 CDI76233.1 - 0.0054 16.4 8.1 0.0076 15.9 5.6 1.3 1 0 0 1 1 1 1 FAM176 family TRAP_alpha PF03896.11 CDI76233.1 - 0.0063 15.5 4.0 0.0063 15.5 2.8 1.2 1 1 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit Zip PF02535.17 CDI76233.1 - 0.01 14.8 2.4 0.013 14.5 1.6 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Gag_spuma PF03276.9 CDI76233.1 - 0.017 13.4 31.0 0.016 13.6 21.5 1.1 1 0 0 1 1 1 0 Spumavirus gag protein Plasmodium_Vir PF05795.6 CDI76233.1 - 0.019 14.1 6.7 0.023 13.9 4.6 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein DUF2052 PF09747.4 CDI76233.1 - 0.048 13.5 24.5 0.068 13.0 17.0 1.2 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) Serinc PF03348.10 CDI76233.1 - 0.049 12.3 11.6 0.053 12.2 8.0 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) CDC45 PF02724.9 CDI76233.1 - 0.058 11.4 20.2 0.07 11.1 14.0 1.0 1 0 0 1 1 1 0 CDC45-like protein Pex14_N PF04695.8 CDI76233.1 - 0.064 13.3 21.9 0.1 12.6 15.2 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Ycf1 PF05758.7 CDI76233.1 - 0.067 10.8 21.6 0.07 10.8 14.9 1.0 1 0 0 1 1 1 0 Ycf1 Peptidase_U57 PF05582.7 CDI76233.1 - 0.094 11.6 13.3 0.11 11.4 9.2 1.2 1 0 0 1 1 1 0 YabG peptidase U57 Raftlin PF15250.1 CDI76233.1 - 0.094 11.2 18.6 0.11 10.9 12.9 1.0 1 0 0 1 1 1 0 Raftlin ABC2_membrane_2 PF12679.2 CDI76233.1 - 0.12 11.1 1.9 0.16 10.7 1.3 1.3 1 0 0 1 1 1 0 ABC-2 family transporter protein HCO3_cotransp PF00955.16 CDI76233.1 - 0.14 10.7 3.5 0.16 10.6 2.4 1.0 1 0 0 1 1 1 0 HCO3- transporter family Folate_carrier PF01770.13 CDI76233.1 - 0.15 10.5 10.0 0.16 10.4 6.9 1.2 1 0 0 1 1 1 0 Reduced folate carrier PAT1 PF09770.4 CDI76233.1 - 0.15 10.2 42.5 0.17 10.0 29.5 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF2370 PF10176.4 CDI76233.1 - 0.17 11.1 8.5 0.2 10.9 5.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) Neur PF00064.13 CDI76233.1 - 0.17 9.9 3.7 0.18 9.8 2.6 1.0 1 0 0 1 1 1 0 Neuraminidase DUF3365 PF11845.3 CDI76233.1 - 0.18 11.6 8.9 0.21 11.4 6.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3365) SAPS PF04499.10 CDI76233.1 - 0.19 10.3 14.2 0.2 10.2 9.8 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Peptidase_S66 PF02016.10 CDI76233.1 - 0.2 10.5 3.4 0.23 10.3 2.4 1.1 1 0 0 1 1 1 0 LD-carboxypeptidase DUF4175 PF13779.1 CDI76233.1 - 0.2 9.3 50.9 0.22 9.1 35.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) DUF1191 PF06697.7 CDI76233.1 - 0.23 10.2 5.6 0.41 9.4 3.9 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1191) Mem_trans PF03547.13 CDI76233.1 - 0.23 9.7 7.8 0.24 9.6 5.4 1.1 1 0 0 1 1 1 0 Membrane transport protein OATP PF03137.15 CDI76233.1 - 0.25 9.3 9.0 0.29 9.1 6.3 1.3 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family DUF4366 PF14283.1 CDI76233.1 - 0.27 10.6 9.4 0.41 10.0 6.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) RP-C_C PF11800.3 CDI76233.1 - 0.3 10.7 16.6 0.36 10.5 11.5 1.2 1 0 0 1 1 1 0 Replication protein C C-terminal region Herpes_env PF01673.13 CDI76233.1 - 0.35 9.3 11.2 0.36 9.3 7.8 1.1 1 0 0 1 1 1 0 Herpesvirus putative major envelope glycoprotein SID-1_RNA_chan PF13965.1 CDI76233.1 - 0.42 8.7 10.3 0.44 8.6 7.1 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 BCS1_N PF08740.6 CDI76233.1 - 0.42 10.1 14.9 0.5 9.9 10.3 1.2 1 0 0 1 1 1 0 BCS1 N terminal Band_3_cyto PF07565.8 CDI76233.1 - 0.44 10.0 18.5 0.53 9.7 12.8 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain DUF3260 PF11658.3 CDI76233.1 - 0.5 8.4 14.7 0.56 8.2 10.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3260) Herpes_DNAp_acc PF04929.7 CDI76233.1 - 0.59 9.0 18.5 0.69 8.8 12.8 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor DUF2561 PF10812.3 CDI76233.1 - 0.61 9.6 3.8 0.75 9.3 2.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2561) Kei1 PF08552.6 CDI76233.1 - 0.62 9.6 10.6 0.84 9.2 7.4 1.2 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 DUF966 PF06136.8 CDI76233.1 - 0.66 9.3 16.6 0.78 9.0 11.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Hid1 PF12722.2 CDI76233.1 - 0.67 7.5 22.1 0.8 7.3 15.3 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF2126 PF09899.4 CDI76233.1 - 0.69 7.8 12.2 0.74 7.7 8.4 1.0 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) Neur_chan_memb PF02932.11 CDI76233.1 - 0.69 9.7 12.8 0.83 9.4 8.8 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF4045 PF13254.1 CDI76233.1 - 0.79 8.9 16.3 0.9 8.7 11.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Presenilin PF01080.12 CDI76233.1 - 1 8.0 11.1 1.1 7.9 7.7 1.1 1 0 0 1 1 1 0 Presenilin Vfa1 PF08432.5 CDI76233.1 - 1.1 9.3 29.8 1.3 8.9 20.7 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 FAM91_C PF14648.1 CDI76233.1 - 1.1 8.0 8.9 1.3 7.7 6.2 1.1 1 0 0 1 1 1 0 FAM91 C-terminus PIH1 PF08190.7 CDI76233.1 - 1.1 8.5 25.1 1.4 8.2 17.4 1.1 1 0 0 1 1 1 0 pre-RNA processing PIH1/Nop17 DUF3853 PF12964.2 CDI76233.1 - 1.2 9.0 15.6 2.5e+03 -1.7 10.8 2.5 1 1 0 1 1 0 0 Protein of unknown function (DUF3853) Glyco_transf_15 PF01793.11 CDI76233.1 - 1.3 7.8 18.3 1.5 7.7 12.7 1.2 1 0 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase DUF2201_N PF13203.1 CDI76233.1 - 1.3 8.0 18.4 1.5 7.9 12.8 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain R_equi_Vir PF05526.6 CDI76233.1 - 1.3 8.5 4.0 1.6 8.3 2.7 1.3 1 0 0 1 1 1 0 Rhodococcus equi virulence-associated protein Med15 PF09606.5 CDI76233.1 - 1.4 7.0 59.1 1.4 6.9 41.0 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Nucleoside_tran PF01733.13 CDI76233.1 - 1.4 8.0 7.2 1.5 7.9 5.0 1.2 1 0 0 1 1 1 0 Nucleoside transporter DUF913 PF06025.7 CDI76233.1 - 1.5 7.5 8.9 1.6 7.3 6.2 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) SPX PF03105.14 CDI76233.1 - 1.5 8.5 20.1 1.8 8.2 13.9 1.1 1 0 0 1 1 1 0 SPX domain AUX_IAA PF02309.11 CDI76233.1 - 1.7 8.3 15.9 2.2 7.9 11.0 1.3 1 0 0 1 1 1 0 AUX/IAA family Adeno_hexon PF01065.14 CDI76233.1 - 1.8 7.3 13.1 1.9 7.2 9.1 1.0 1 0 0 1 1 1 0 Hexon, adenovirus major coat protein, N-terminal domain UPF0565 PF10561.4 CDI76233.1 - 1.8 7.3 13.5 2.3 7.0 9.4 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0565 PPP4R2 PF09184.6 CDI76233.1 - 1.8 8.0 16.5 2.2 7.7 11.4 1.1 1 0 0 1 1 1 0 PPP4R2 TFIIA PF03153.8 CDI76233.1 - 1.8 8.3 34.6 2 8.2 24.0 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit FemAB PF02388.11 CDI76233.1 - 2.5 6.6 21.3 2.8 6.5 14.8 1.1 1 0 0 1 1 1 0 FemAB family YfhO PF09586.5 CDI76233.1 - 2.7 5.9 10.7 2.8 5.8 7.4 1.2 1 0 0 1 1 1 0 Bacterial membrane protein YfhO DUF2828 PF11443.3 CDI76233.1 - 2.7 6.1 17.2 2.9 5.9 11.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Peptidase_S64 PF08192.6 CDI76233.1 - 2.7 6.1 16.3 3.2 5.9 11.3 1.0 1 0 0 1 1 1 0 Peptidase family S64 Glyco_transf_6 PF03414.8 CDI76233.1 - 2.9 6.2 10.5 3.2 6.1 7.3 1.2 1 0 0 1 1 1 0 Glycosyltransferase family 6 Rtt102p PF09510.5 CDI76233.1 - 3 7.8 15.6 3.6 7.5 10.8 1.1 1 0 0 1 1 1 0 Rtt102p-like transcription regulator protein Tetraspannin PF00335.15 CDI76233.1 - 3 7.0 5.2 3 7.0 3.6 1.1 1 0 0 1 1 1 0 Tetraspanin family MRP-S31 PF15433.1 CDI76233.1 - 3.1 7.1 26.4 3.9 6.8 18.3 1.1 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 DUF605 PF04652.11 CDI76233.1 - 3.2 7.0 24.8 3.6 6.8 17.2 1.1 1 0 0 1 1 1 0 Vta1 like HemX PF04375.9 CDI76233.1 - 3.4 6.1 34.9 3.6 6.0 24.2 1.1 1 0 0 1 1 1 0 HemX BNR_3 PF13859.1 CDI76233.1 - 3.5 6.6 8.4 4.1 6.3 5.8 1.2 1 0 0 1 1 1 0 BNR repeat-like domain DUF1510 PF07423.6 CDI76233.1 - 3.7 6.8 28.2 7.2 5.9 19.5 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1510) Senescence_reg PF04520.8 CDI76233.1 - 3.7 8.0 14.7 5 7.5 10.2 1.2 1 0 0 1 1 1 0 Senescence regulator DHHW PF14286.1 CDI76233.1 - 3.8 6.7 17.2 4.6 6.4 11.9 1.0 1 0 0 1 1 1 0 DHHW protein YqfQ PF14181.1 CDI76233.1 - 4.1 7.4 26.5 0.38 10.7 14.9 1.7 2 0 0 2 2 2 0 YqfQ-like protein Dynamin_N PF00350.18 CDI76233.1 - 4.2 7.1 12.4 5.6 6.7 8.6 1.3 1 0 0 1 1 1 0 Dynamin family Spore_YhcN_YlaJ PF09580.5 CDI76233.1 - 4.4 7.3 19.6 5.4 7.0 13.6 1.2 1 0 0 1 1 1 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) K_trans PF02705.11 CDI76233.1 - 4.5 5.5 7.0 5.2 5.3 4.8 1.0 1 0 0 1 1 1 0 K+ potassium transporter Shisa PF13908.1 CDI76233.1 - 5.1 7.2 17.3 6.9 6.8 12.0 1.2 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator RBP_receptor PF14752.1 CDI76233.1 - 6.3 4.9 8.6 6.8 4.8 5.9 1.2 1 0 0 1 1 1 0 Retinol binding protein receptor eIF-3_zeta PF05091.7 CDI76233.1 - 7 5.1 27.9 8.2 4.9 19.3 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) FliP PF00813.15 CDI76233.1 - 8.3 6.0 8.9 9.1 5.9 6.1 1.2 1 0 0 1 1 1 0 FliP family DUF1800 PF08811.6 CDI76233.1 - 9.3 5.0 23.1 10 4.9 16.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1800) Paramyxo_ncap PF00973.14 CDI76233.1 - 9.5 4.7 17.1 10 4.6 11.8 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein PDEase_I PF00233.14 CDI76236.1 - 6.5e-21 75.1 0.4 1.1e-20 74.4 0.3 1.3 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase HD PF01966.17 CDI76236.1 - 0.011 15.7 0.5 0.049 13.6 0.0 2.1 2 0 0 2 2 2 0 HD domain MCPVI PF02993.9 CDI76236.1 - 0.074 13.1 1.3 0.098 12.7 0.9 1.1 1 0 0 1 1 1 0 Minor capsid protein VI Trypan_PARP PF05887.6 CDI76236.1 - 2 8.2 10.9 3 7.6 7.6 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Presenilin PF01080.12 CDI76242.1 - 0.25 10.1 15.6 0.22 10.2 8.8 1.9 2 0 0 2 2 2 0 Presenilin Nse4_C PF08743.5 CDI76254.1 - 0.0045 16.9 1.5 0.0045 16.9 1.0 1.9 2 0 0 2 2 2 1 Nse4 C-terminal DUF788 PF05620.6 CDI76254.1 - 0.015 15.2 1.3 0.015 15.2 0.9 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF788) DUF3357 PF11837.3 CDI76254.1 - 0.021 14.6 0.7 1.4 8.7 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3357) 7tm_1 PF00001.16 CDI76254.1 - 0.025 13.7 0.9 0.031 13.4 0.6 1.1 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) DUF4199 PF13858.1 CDI76254.1 - 0.048 13.5 6.8 0.087 12.7 3.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4199) YfhO PF09586.5 CDI76254.1 - 0.05 11.6 2.1 0.057 11.4 1.4 1.1 1 0 0 1 1 1 0 Bacterial membrane protein YfhO FHIPEP PF00771.15 CDI76254.1 - 0.06 11.6 3.3 0.069 11.4 2.3 1.1 1 0 0 1 1 1 0 FHIPEP family MarC PF01914.12 CDI76254.1 - 0.26 10.3 1.7 6.1 5.9 0.0 2.1 2 0 0 2 2 2 0 MarC family integral membrane protein RRN9 PF10680.4 CDI76254.1 - 0.57 9.9 3.8 1.4 8.6 1.5 2.1 2 0 0 2 2 2 0 RNA polymerase I specific transcription initiation factor Conotoxin PF02950.12 CDI76254.1 - 0.76 10.6 6.8 3.1 8.6 0.8 2.1 2 0 0 2 2 2 0 Conotoxin Serinc PF03348.10 CDI76254.1 - 0.77 8.3 5.1 0.18 10.4 0.9 1.7 2 0 0 2 2 2 0 Serine incorporator (Serinc) C1q PF00386.16 CDI76254.1 - 1.4 8.9 7.5 0.37 10.7 2.1 1.9 2 0 0 2 2 2 0 C1q domain Ctr PF04145.10 CDI76254.1 - 1.7 8.6 4.1 2.8 7.9 1.2 1.9 2 0 0 2 2 2 0 Ctr copper transporter family DivIC PF04977.10 CDI76254.1 - 4.2 6.9 26.1 4.3 6.8 2.4 2.1 2 0 0 2 2 2 0 Septum formation initiator EphA2_TM PF14575.1 CDI76254.1 - 5.5 7.4 9.6 36 4.8 0.0 2.3 2 1 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain DUF2489 PF10675.4 CDI76254.1 - 6.2 6.5 26.3 0.09 12.4 0.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2489) SprA-related PF12118.3 CDI76255.1 - 0.0037 16.6 52.9 0.0047 16.3 36.7 1.0 1 0 0 1 1 1 1 SprA-related family SAGA-Tad1 PF12767.2 CDI76255.1 - 0.24 11.0 31.9 0.29 10.7 22.1 1.2 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit Utp14 PF04615.8 CDI76255.1 - 0.3 9.2 38.3 0.35 8.9 26.5 1.0 1 0 0 1 1 1 0 Utp14 protein AAA_23 PF13476.1 CDI76255.1 - 0.58 10.4 24.8 0.71 10.1 17.2 1.1 1 0 0 1 1 1 0 AAA domain OmpH PF03938.9 CDI76255.1 - 1 9.2 32.5 1.3 8.9 22.5 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Med15 PF09606.5 CDI76255.1 - 2.2 6.4 62.2 2.3 6.3 43.1 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Activator_LAG-3 PF11498.3 CDI76255.1 - 3.6 6.2 51.2 4.7 5.8 35.5 1.3 1 0 0 1 1 1 0 Transcriptional activator LAG-3 rve PF00665.21 CDI76259.1 - 2.6e-19 69.4 0.0 6.4e-19 68.2 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.1 CDI76259.1 - 0.096 12.2 0.2 0.84 9.2 0.1 2.3 2 0 0 2 2 2 0 Integrase core domain DUF572 PF04502.8 CDI76293.1 - 0.0033 16.7 8.6 0.0047 16.1 5.9 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF572) Pol_alpha_B_N PF08418.5 CDI76293.1 - 0.044 13.3 2.0 0.058 12.9 1.4 1.2 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal Abhydrolase_5 PF12695.2 CDI76293.1 - 0.063 13.0 3.9 0.083 12.6 2.7 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase family PTS_EIIC PF02378.13 CDI76293.1 - 0.13 11.1 0.8 0.2 10.4 0.6 1.4 1 0 0 1 1 1 0 Phosphotransferase system, EIIC Draxin PF15550.1 CDI76293.1 - 0.23 11.0 5.1 0.31 10.6 3.6 1.2 1 0 0 1 1 1 0 Draxin DUF966 PF06136.8 CDI76293.1 - 1.4 8.2 5.9 1.7 7.9 4.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) TORC_M PF12885.2 CDI76293.1 - 4.5 7.0 8.2 2.7 7.7 1.6 2.3 2 0 0 2 2 2 0 Transducer of regulated CREB activity middle domain Ribosomal_60s PF00428.14 CDI76294.1 - 0.48 10.8 9.2 0.58 10.5 6.4 1.3 1 0 0 1 1 1 0 60s Acidic ribosomal protein F420_oxidored PF03807.12 CDI76294.1 - 0.82 10.1 4.5 1 9.8 3.1 1.2 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent DUF4647 PF15504.1 CDI76294.1 - 1.3 7.8 21.7 1.4 7.6 15.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4647) Glycophorin_A PF01102.13 CDI76294.1 - 4.3 7.1 8.3 5.8 6.7 5.8 1.3 1 0 0 1 1 1 0 Glycophorin A Alg14 PF08660.6 CDI76294.1 - 5.2 7.0 8.7 9.6 6.1 6.0 1.6 1 1 0 1 1 1 0 Oligosaccharide biosynthesis protein Alg14 like DUF2422 PF10337.4 CDI76294.1 - 7.1 5.2 11.3 9.7 4.8 7.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2422) DUF3123 PF11321.3 CDI76294.1 - 8.8 6.6 10.5 13 6.1 7.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3123) TSP_1 PF00090.14 CDI76316.1 - 5.1e-107 349.8 235.4 1e-11 44.7 3.1 21.1 20 1 0 20 20 20 17 Thrombospondin type 1 domain Notch PF00066.12 CDI76316.1 - 3.6e-27 94.3 103.6 2.8e-09 37.1 9.8 8.7 7 0 0 7 7 7 4 LNR domain DUF4381 PF14316.1 CDI76316.1 - 0.054 13.6 0.1 0.14 12.2 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) HemX PF04375.9 CDI76316.1 - 0.14 10.7 3.2 0.24 9.9 2.2 1.2 1 0 0 1 1 1 0 HemX RIO1 PF01163.17 CDI76333.1 - 1.9e-10 40.3 0.0 4.5e-10 39.1 0.0 1.6 1 0 0 1 1 1 1 RIO1 family RNA_pol_3_Rpc31 PF11705.3 CDI76333.1 - 0.0046 16.9 19.3 0.0046 16.9 13.4 2.5 3 0 0 3 3 3 1 DNA-directed RNA polymerase III subunit Rpc31 AraC_N PF06719.8 CDI76333.1 - 0.057 12.7 1.5 0.095 11.9 1.1 1.3 1 0 0 1 1 1 0 AraC-type transcriptional regulator N-terminus DUF668 PF05003.7 CDI76333.1 - 0.068 13.3 0.8 0.21 11.8 0.5 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF668) Utp14 PF04615.8 CDI76335.1 - 0.013 13.6 56.5 0.015 13.4 39.1 1.1 1 0 0 1 1 1 0 Utp14 protein PAT1 PF09770.4 CDI76335.1 - 1.2 7.3 71.9 1.6 6.8 49.8 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Med15 PF09606.5 CDI76335.1 - 1.6 6.8 88.0 2.5 6.2 61.0 1.3 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Shadoo PF14999.1 CDI76347.1 - 0.017 14.9 2.0 0.017 14.9 1.4 2.6 2 1 1 3 3 3 0 Shadow of prion protein, neuroprotective DUF389 PF04087.9 CDI76347.1 - 0.046 13.6 1.1 0.089 12.7 0.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF389) PAP2 PF01569.16 CDI76347.1 - 0.048 13.3 0.1 0.12 12.0 0.0 1.7 2 0 0 2 2 2 0 PAP2 superfamily EI24 PF07264.6 CDI76348.1 - 1.2e-08 34.6 1.7 0.0011 18.4 0.0 2.5 2 0 0 2 2 2 2 Etoposide-induced protein 2.4 (EI24) DUF2076 PF09849.4 CDI76348.1 - 0.68 9.9 56.2 0.038 14.0 18.1 3.1 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2076) Zip PF02535.17 CDI76348.1 - 1.5 7.7 13.1 3.5 6.5 9.1 1.8 1 1 0 1 1 1 0 ZIP Zinc transporter SR-25 PF10500.4 CDI76348.1 - 5.7 6.3 22.0 0.84 9.0 0.5 2.5 2 1 0 2 2 2 0 Nuclear RNA-splicing-associated protein ETRAMP PF09716.5 CDI76349.1 - 0.017 15.0 0.3 0.017 15.0 0.2 2.9 1 1 1 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) zf-C3HC4 PF00097.20 CDI76349.1 - 0.041 13.5 1.6 0.16 11.6 1.1 2.2 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Ribosomal_60s PF00428.14 CDI76349.1 - 1.6 9.1 8.9 0.15 12.5 3.1 1.5 2 0 0 2 2 2 0 60s Acidic ribosomal protein MRP-S31 PF15433.1 CDI76349.1 - 2.9 7.2 35.9 3.6 6.9 24.9 1.2 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 DUF605 PF04652.11 CDI76360.1 - 0.93 8.8 50.4 1.2 8.4 34.9 1.1 1 0 0 1 1 1 0 Vta1 like Utp14 PF04615.8 CDI76360.1 - 2.4 6.1 44.2 3.3 5.7 30.7 1.1 1 0 0 1 1 1 0 Utp14 protein DUF1777 PF08648.7 CDI76363.1 - 0.00068 19.4 62.3 0.0037 17.0 16.6 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF1777) TT_ORF1 PF02956.9 CDI76364.1 - 0.017 13.5 12.5 0.02 13.3 8.7 1.0 1 0 0 1 1 1 0 TT viral orf 1 SelP_N PF04592.9 CDI76364.1 - 0.04 13.2 10.8 0.05 12.9 7.5 1.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Rtf2 PF04641.7 CDI76364.1 - 0.068 12.3 7.7 0.079 12.1 5.4 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger DUF1183 PF06682.7 CDI76364.1 - 0.13 11.8 9.1 0.15 11.6 6.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) Folate_carrier PF01770.13 CDI76364.1 - 0.17 10.3 4.3 0.19 10.2 3.0 1.1 1 0 0 1 1 1 0 Reduced folate carrier DUF1180 PF06679.7 CDI76364.1 - 0.21 11.4 0.9 0.25 11.1 0.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Herpes_DNAp_acc PF04929.7 CDI76364.1 - 0.26 10.1 12.3 0.32 9.9 8.5 1.0 1 0 0 1 1 1 0 Herpes DNA replication accessory factor FLO_LFY PF01698.11 CDI76364.1 - 0.27 10.0 8.9 0.31 9.8 6.1 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein TMEM219 PF14940.1 CDI76364.1 - 0.3 10.1 3.1 0.36 9.8 2.2 1.1 1 0 0 1 1 1 0 Transmembrane 219 Zip PF02535.17 CDI76364.1 - 0.4 9.6 5.9 0.42 9.5 4.1 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter RP-C_C PF11800.3 CDI76364.1 - 0.42 10.2 11.3 0.49 10.0 7.8 1.0 1 0 0 1 1 1 0 Replication protein C C-terminal region DDHD PF02862.12 CDI76364.1 - 0.44 10.2 8.2 0.51 10.0 5.7 1.1 1 0 0 1 1 1 0 DDHD domain PAT1 PF09770.4 CDI76364.1 - 0.46 8.6 36.1 0.49 8.5 25.0 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 RR_TM4-6 PF06459.7 CDI76364.1 - 0.47 10.2 9.7 0.55 10.0 6.7 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Spore_coat_CotO PF14153.1 CDI76364.1 - 0.49 9.8 16.1 0.59 9.5 11.2 1.2 1 0 0 1 1 1 0 Spore coat protein CotO eIF-3_zeta PF05091.7 CDI76364.1 - 0.65 8.5 12.2 0.67 8.5 8.5 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Presenilin PF01080.12 CDI76364.1 - 0.77 8.5 7.2 0.82 8.4 5.0 1.1 1 0 0 1 1 1 0 Presenilin Band_3_cyto PF07565.8 CDI76364.1 - 0.79 9.1 12.0 0.9 9.0 8.3 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Baculo_PP31 PF05311.6 CDI76364.1 - 0.8 8.9 8.1 0.87 8.7 5.6 1.1 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) AUX_IAA PF02309.11 CDI76364.1 - 0.95 9.1 7.5 1.2 8.8 5.2 1.1 1 0 0 1 1 1 0 AUX/IAA family DUF4512 PF14975.1 CDI76364.1 - 1.1 10.1 6.0 1.5 9.7 4.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4512) Hid1 PF12722.2 CDI76364.1 - 1.3 6.6 12.0 1.3 6.5 8.3 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Neur_chan_memb PF02932.11 CDI76364.1 - 1.5 8.6 9.2 1.6 8.5 6.4 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Endonuc_Holl PF10107.4 CDI76364.1 - 1.5 8.5 9.0 2 8.1 6.2 1.2 1 0 0 1 1 1 0 Endonuclease related to archaeal Holliday junction resolvase DUF3260 PF11658.3 CDI76364.1 - 1.6 6.8 8.4 1.6 6.7 5.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3260) Gag_spuma PF03276.9 CDI76364.1 - 2 6.6 20.7 2.4 6.3 14.3 1.1 1 0 0 1 1 1 0 Spumavirus gag protein Kei1 PF08552.6 CDI76364.1 - 2.2 7.8 7.3 2.9 7.5 5.1 1.3 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 Med15 PF09606.5 CDI76364.1 - 3.4 5.7 43.7 3.7 5.6 30.3 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Myco_haema PF05692.7 CDI76364.1 - 3.8 6.1 12.2 0.17 10.5 0.2 1.9 1 1 1 2 2 2 0 Mycoplasma haemagglutinin TFIIA PF03153.8 CDI76364.1 - 3.9 7.2 24.6 4.6 7.0 17.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4175 PF13779.1 CDI76364.1 - 4.1 4.9 38.4 5.2 4.6 26.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) MRI PF15325.1 CDI76364.1 - 5.7 7.9 6.2 8.1 7.4 4.3 1.2 1 0 0 1 1 1 0 Modulator of retrovirus infection DUF3357 PF11837.3 CDI76364.1 - 6.9 6.5 8.7 2.5 7.9 0.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF3357) Dicty_REP PF05086.7 CDI76364.1 - 7 4.2 11.6 7.8 4.1 8.1 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein MDFI PF15316.1 CDI76364.1 - 7.6 6.4 8.2 13 5.7 5.7 1.3 1 0 0 1 1 1 0 MyoD family inhibitor AAA_23 PF13476.1 CDI76364.1 - 9 6.5 17.2 11 6.2 11.9 1.1 1 0 0 1 1 1 0 AAA domain FAM150 PF15129.1 CDI76371.1 - 0.056 13.3 0.2 0.1 12.4 0.2 1.5 1 0 0 1 1 1 0 FAM150 family DUF3995 PF13160.1 CDI76371.1 - 0.26 11.3 3.5 0.46 10.5 2.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3995) CBFB_NFYA PF02045.10 CDI76371.1 - 0.47 11.0 3.8 0.36 11.3 0.5 2.1 2 0 0 2 2 2 0 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B DUF3597 PF12200.3 CDI76371.1 - 0.67 10.3 6.2 0.21 11.9 2.6 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3597) Glyco_hydro_9 PF00759.14 CDI76371.1 - 3.6 6.3 7.3 5.1 5.8 5.1 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 9 RskA PF10099.4 CDI76371.1 - 4.3 7.0 21.9 0.058 13.1 9.2 1.8 1 1 1 2 2 2 0 Anti-sigma-K factor rskA TSA PF03249.8 CDI76371.1 - 9.1 4.6 11.9 12 4.3 8.2 1.2 1 0 0 1 1 1 0 Type specific antigen Rifin_STEVOR PF02009.11 CDI76372.1 - 3.3 7.2 7.6 4.3 6.8 5.3 1.2 1 0 0 1 1 1 0 Rifin/stevor family DUF4404 PF14357.1 CDI76376.1 - 0.0019 18.5 0.5 0.0026 18.1 0.4 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4404) DUF3558 PF12079.3 CDI76376.1 - 0.058 13.0 0.1 0.065 12.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3558) Pribosyltran_N PF13793.1 CDI76390.1 - 9.5e-47 157.5 0.2 1.6e-45 153.5 0.0 2.3 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.1 CDI76390.1 - 1.5e-35 122.5 1.0 2.8e-35 121.7 0.7 1.4 1 0 0 1 1 1 1 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 CDI76390.1 - 4e-10 39.4 0.6 1.3e-09 37.8 0.4 1.9 1 1 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 CDI76390.1 - 0.00054 19.2 0.0 0.00089 18.5 0.0 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase PAP1 PF08601.5 CDI76391.1 - 1.8 8.1 25.2 2.1 7.9 17.5 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 PAT1 PF09770.4 CDI76391.1 - 3 5.9 27.0 3.6 5.6 18.7 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF1631 PF07793.6 CDI76391.1 - 3.2 5.7 16.4 3.6 5.5 11.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) CDC73 PF05179.9 CDI76391.1 - 6.8 5.9 12.9 7.7 5.7 9.0 1.3 1 0 0 1 1 1 0 RNA pol II accessory factor, Cdc73 family DUF1510 PF07423.6 CDI76392.1 - 3.2e-05 23.4 10.4 3.6e-05 23.2 7.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) SpoIIIAH PF12685.2 CDI76392.1 - 0.00026 20.5 8.6 0.0003 20.3 6.0 1.1 1 0 0 1 1 1 1 SpoIIIAH-like protein FAM176 PF14851.1 CDI76392.1 - 0.00034 20.3 6.1 0.0004 20.1 4.2 1.0 1 0 0 1 1 1 1 FAM176 family TRAP_alpha PF03896.11 CDI76392.1 - 0.002 17.1 3.5 0.0022 17.0 2.5 1.0 1 0 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit T2SM PF04612.7 CDI76392.1 - 0.0032 17.2 30.2 0.0048 16.6 21.0 1.3 1 0 0 1 1 1 1 Type II secretion system (T2SS), protein M SID-1_RNA_chan PF13965.1 CDI76392.1 - 0.004 15.3 8.9 0.0041 15.3 6.2 1.0 1 0 0 1 1 1 1 dsRNA-gated channel SID-1 DUF843 PF05814.6 CDI76392.1 - 0.0068 16.1 1.6 0.0068 16.1 1.1 1.7 1 1 1 2 2 2 1 Baculovirus protein of unknown function (DUF843) Ctr PF04145.10 CDI76392.1 - 0.0095 15.9 7.0 0.011 15.7 4.8 1.2 1 0 0 1 1 1 1 Ctr copper transporter family DUF3530 PF12048.3 CDI76392.1 - 0.0099 14.8 26.2 0.014 14.4 18.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3530) Serinc PF03348.10 CDI76392.1 - 0.01 14.5 12.6 0.011 14.4 8.7 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) RIC3 PF15361.1 CDI76392.1 - 0.026 14.7 14.9 0.031 14.5 10.3 1.1 1 0 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 Neur_chan_memb PF02932.11 CDI76392.1 - 0.038 13.8 9.8 0.042 13.7 6.8 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF4512 PF14975.1 CDI76392.1 - 0.039 14.7 6.8 0.045 14.5 4.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4512) DUF4446 PF14584.1 CDI76392.1 - 0.048 13.5 13.5 0.05 13.4 9.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) Ni_hydr_CYTB PF01292.15 CDI76392.1 - 0.048 13.0 0.2 0.052 12.9 0.2 1.2 1 0 0 1 1 1 0 Prokaryotic cytochrome b561 Pex24p PF06398.6 CDI76392.1 - 0.053 12.3 1.2 0.056 12.2 0.8 1.1 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin OAD_gamma PF04277.8 CDI76392.1 - 0.072 13.4 2.4 0.17 12.2 1.7 1.7 1 1 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain Stig1 PF04885.8 CDI76392.1 - 0.074 13.2 5.9 0.1 12.8 4.1 1.2 1 0 0 1 1 1 0 Stigma-specific protein, Stig1 DUF4131 PF13567.1 CDI76392.1 - 0.085 12.2 11.5 0.099 12.0 7.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) Cytochrom_B_N PF00033.14 CDI76392.1 - 0.093 12.0 4.1 0.14 11.4 2.8 1.4 1 1 0 1 1 1 0 Cytochrome b(N-terminal)/b6/petB Peptidase_S49_N PF08496.5 CDI76392.1 - 0.097 12.4 13.9 0.13 12.0 9.6 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Folate_carrier PF01770.13 CDI76392.1 - 0.098 11.1 11.2 0.1 11.0 7.7 1.0 1 0 0 1 1 1 0 Reduced folate carrier OATP PF03137.15 CDI76392.1 - 0.098 10.6 11.5 0.1 10.6 8.0 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family DUF2514 PF10721.4 CDI76392.1 - 0.1 12.2 20.2 0.12 12.0 14.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) NicO PF03824.11 CDI76392.1 - 0.11 11.8 0.2 0.11 11.7 0.1 1.1 1 0 0 1 1 1 0 High-affinity nickel-transport protein Baculo_PP31 PF05311.6 CDI76392.1 - 0.15 11.3 14.7 0.16 11.2 10.2 1.1 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) MLANA PF14991.1 CDI76392.1 - 0.17 11.8 1.2 0.22 11.5 0.9 1.3 1 0 0 1 1 1 0 Protein melan-A Gastrin PF00918.12 CDI76392.1 - 0.19 12.5 23.2 0.23 12.2 16.1 1.1 1 0 0 1 1 1 0 Gastrin/cholecystokinin family Ycf1 PF05758.7 CDI76392.1 - 0.2 9.3 16.6 0.21 9.2 11.5 1.0 1 0 0 1 1 1 0 Ycf1 Nucleoside_tran PF01733.13 CDI76392.1 - 0.22 10.6 6.8 0.22 10.6 4.7 1.0 1 0 0 1 1 1 0 Nucleoside transporter IncA PF04156.9 CDI76392.1 - 0.24 10.9 39.4 0.28 10.7 27.3 1.1 1 0 0 1 1 1 0 IncA protein SDF PF00375.13 CDI76392.1 - 0.31 9.7 1.4 0.45 9.2 0.9 1.4 1 1 0 1 1 1 0 Sodium:dicarboxylate symporter family DUF3260 PF11658.3 CDI76392.1 - 0.32 9.1 17.8 0.32 9.1 12.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3260) Herpes_glycop PF01528.11 CDI76392.1 - 0.34 9.5 5.6 0.38 9.4 3.9 1.2 1 0 0 1 1 1 0 Herpesvirus glycoprotein M Mem_trans PF03547.13 CDI76392.1 - 0.37 9.0 9.9 0.4 8.9 6.9 1.1 1 0 0 1 1 1 0 Membrane transport protein PIG-P PF08510.7 CDI76392.1 - 0.38 10.3 6.1 0.71 9.5 4.2 1.5 1 1 0 1 1 1 0 PIG-P DUF913 PF06025.7 CDI76392.1 - 0.39 9.4 7.2 0.4 9.3 5.0 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) YfhO PF09586.5 CDI76392.1 - 0.4 8.6 13.7 0.47 8.4 9.5 1.2 1 0 0 1 1 1 0 Bacterial membrane protein YfhO DUF3365 PF11845.3 CDI76392.1 - 0.51 10.1 13.0 0.57 10.0 9.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3365) FHIPEP PF00771.15 CDI76392.1 - 0.53 8.5 14.5 0.7 8.1 10.1 1.2 1 0 0 1 1 1 0 FHIPEP family DUF3357 PF11837.3 CDI76392.1 - 0.56 10.0 12.6 13 5.7 8.7 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF3357) TAS2R PF05296.8 CDI76392.1 - 0.6 8.9 3.1 0.65 8.8 2.2 1.1 1 0 0 1 1 1 0 Mammalian taste receptor protein (TAS2R) ABC2_membrane_2 PF12679.2 CDI76392.1 - 0.64 8.8 7.6 0.83 8.4 5.3 1.3 1 0 0 1 1 1 0 ABC-2 family transporter protein Shisa PF13908.1 CDI76392.1 - 0.82 9.8 19.3 0.82 9.8 13.4 1.1 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Pap_E4 PF02711.9 CDI76392.1 - 0.83 10.5 19.5 1.1 10.1 13.5 1.2 1 0 0 1 1 1 0 E4 protein Neur PF00064.13 CDI76392.1 - 0.85 7.6 6.3 0.92 7.5 4.4 1.0 1 0 0 1 1 1 0 Neuraminidase Tetraspannin PF00335.15 CDI76392.1 - 0.86 8.8 10.0 0.97 8.6 6.9 1.1 1 0 0 1 1 1 0 Tetraspanin family Endonuc_Holl PF10107.4 CDI76392.1 - 0.92 9.1 19.3 1.1 8.9 13.4 1.0 1 0 0 1 1 1 0 Endonuclease related to archaeal Holliday junction resolvase RP-C_C PF11800.3 CDI76392.1 - 1 9.0 15.0 1 9.0 10.4 1.0 1 0 0 1 1 1 0 Replication protein C C-terminal region RICTOR_N PF14664.1 CDI76392.1 - 1.1 7.7 7.6 1.2 7.6 5.3 1.0 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR, N-term GRP PF07172.6 CDI76392.1 - 1.2 9.6 12.4 6.4 7.3 8.6 1.9 1 1 0 1 1 1 0 Glycine rich protein family Peptidase_M56 PF05569.6 CDI76392.1 - 1.2 8.0 5.2 1.3 7.9 3.6 1.1 1 0 0 1 1 1 0 BlaR1 peptidase M56 DUF2370 PF10176.4 CDI76392.1 - 1.5 8.1 10.3 1.7 7.9 7.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) EphA2_TM PF14575.1 CDI76392.1 - 1.6 9.2 19.6 1.3e+03 -0.2 13.6 2.2 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF2561 PF10812.3 CDI76392.1 - 1.6 8.3 3.4 1.6 8.2 2.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2561) Raftlin PF15250.1 CDI76392.1 - 1.6 7.1 17.4 1.7 7.0 12.0 1.0 1 0 0 1 1 1 0 Raftlin OSTbeta PF15048.1 CDI76392.1 - 1.6 8.8 13.9 2.4 8.2 9.6 1.3 1 0 0 1 1 1 0 Organic solute transporter subunit beta protein Otopetrin PF03189.8 CDI76392.1 - 1.8 7.4 7.9 1.9 7.3 5.5 1.1 1 0 0 1 1 1 0 Otopetrin DUF3450 PF11932.3 CDI76392.1 - 1.9 7.7 35.9 2.1 7.5 24.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) K_trans PF02705.11 CDI76392.1 - 2.2 6.5 5.8 2.6 6.3 4.0 1.1 1 0 0 1 1 1 0 K+ potassium transporter Herpes_DNAp_acc PF04929.7 CDI76392.1 - 2.3 7.1 15.4 2.6 6.9 10.7 1.0 1 0 0 1 1 1 0 Herpes DNA replication accessory factor ALG3 PF05208.8 CDI76392.1 - 2.5 7.2 11.1 2.6 7.2 7.7 1.1 1 0 0 1 1 1 0 ALG3 protein ETRAMP PF09716.5 CDI76392.1 - 2.7 8.0 6.3 6.8 6.7 4.4 1.7 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) FliP PF00813.15 CDI76392.1 - 2.8 7.6 15.0 3.2 7.4 10.4 1.0 1 0 0 1 1 1 0 FliP family Cas1_AcylT PF07779.7 CDI76392.1 - 2.8 6.3 6.8 3 6.1 4.7 1.2 1 0 0 1 1 1 0 10 TM Acyl Transferase domain found in Cas1p Tim54 PF11711.3 CDI76392.1 - 2.8 6.4 13.9 2.9 6.3 9.7 1.0 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 AUX_IAA PF02309.11 CDI76392.1 - 3.5 7.3 16.5 3.9 7.1 11.5 1.0 1 0 0 1 1 1 0 AUX/IAA family DUF2615 PF11027.3 CDI76392.1 - 3.8 7.4 17.0 2e+02 1.9 12.0 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF2615) DUF2828 PF11443.3 CDI76392.1 - 3.8 5.5 15.2 4.1 5.4 10.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Conotoxin PF02950.12 CDI76392.1 - 3.8 8.3 23.9 1.8e+02 3.0 16.5 2.2 1 1 0 1 1 1 0 Conotoxin Sec62 PF03839.11 CDI76392.1 - 3.8 6.8 15.3 4.1 6.7 10.6 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 Tmemb_9 PF05434.6 CDI76392.1 - 4.2 7.1 22.0 4.9 6.8 15.3 1.0 1 0 0 1 1 1 0 TMEM9 BORG_CEP PF14957.1 CDI76392.1 - 4.5 8.2 12.0 5.6 7.9 8.3 1.1 1 0 0 1 1 1 0 Cdc42 effector UPF0565 PF10561.4 CDI76392.1 - 4.6 6.0 15.4 4.8 5.9 10.7 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0565 ODV-E18 PF10717.4 CDI76392.1 - 4.7 6.7 6.4 10 5.6 4.4 1.8 1 1 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 Rtf2 PF04641.7 CDI76392.1 - 5.7 6.0 19.6 6.7 5.8 13.6 1.0 1 0 0 1 1 1 0 Rtf2 RING-finger DUF2946 PF11162.3 CDI76392.1 - 6.3 7.0 15.4 9.8 6.4 10.7 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2946) HGTP_anticodon2 PF12745.2 CDI76392.1 - 6.5 5.8 19.5 7 5.7 13.5 1.0 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs Het-C PF07217.6 CDI76392.1 - 6.6 4.7 12.2 7.5 4.6 8.5 1.2 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C Trp_oprn_chp PF09534.5 CDI76392.1 - 7.9 6.0 6.4 18 4.8 4.4 1.7 1 1 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) YABBY PF04690.8 CDI76392.1 - 8.3 6.6 16.0 9.2 6.4 11.1 1.0 1 0 0 1 1 1 0 YABBY protein NARP1 PF12569.3 CDI76392.1 - 9.3 4.8 21.3 10 4.7 14.8 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DUF4220 PF13968.1 CDI76392.1 - 9.3 5.2 9.6 9.8 5.1 6.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4220) HCO3_cotransp PF00955.16 CDI76392.1 - 9.3 4.7 6.4 9.2 4.7 4.4 1.1 1 0 0 1 1 1 0 HCO3- transporter family Pex16 PF08610.5 CDI76392.1 - 9.5 5.1 19.4 12 4.7 13.4 1.1 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) Conotoxin PF02950.12 CDI76395.1 - 0.00095 19.9 0.1 0.00095 19.9 0.1 3.7 3 1 1 4 4 4 1 Conotoxin Viral_Beta_CD PF04530.7 CDI76395.1 - 0.0073 16.4 1.1 0.0073 16.4 0.7 2.2 3 0 0 3 3 2 1 Viral Beta C/D like family IncA PF04156.9 CDI76395.1 - 0.008 15.7 11.1 0.008 15.7 7.7 2.4 2 1 0 2 2 2 1 IncA protein Ribosomal_60s PF00428.14 CDI76395.1 - 0.012 16.0 9.3 0.012 16.0 6.4 2.2 2 0 0 2 2 2 0 60s Acidic ribosomal protein RskA PF10099.4 CDI76395.1 - 0.012 15.3 17.8 0.11 12.1 6.0 2.4 2 1 0 2 2 2 0 Anti-sigma-K factor rskA SprA-related PF12118.3 CDI76395.1 - 0.072 12.4 37.9 0.25 10.6 4.5 2.2 2 0 0 2 2 2 0 SprA-related family RAP1 PF07218.6 CDI76395.1 - 0.088 10.9 2.9 0.13 10.3 2.0 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DUF912 PF06024.7 CDI76395.1 - 0.11 12.6 14.0 0.25 11.4 2.1 3.0 2 2 1 3 3 3 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF4259 PF14078.1 CDI76395.1 - 0.27 11.7 7.2 8.7 6.8 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4259) EphA2_TM PF14575.1 CDI76395.1 - 0.43 11.0 0.0 0.43 11.0 0.0 3.3 3 1 0 3 3 2 0 Ephrin type-A receptor 2 transmembrane domain CD20 PF04103.10 CDI76395.1 - 0.68 9.8 11.2 0.12 12.3 1.3 2.9 2 1 1 3 3 3 0 CD20-like family Peptidase_S49_N PF08496.5 CDI76395.1 - 1.1 9.0 8.1 7.6 6.3 3.5 2.3 2 0 0 2 2 2 0 Peptidase family S49 N-terminal AAA_23 PF13476.1 CDI76395.1 - 2.5 8.4 13.8 3.8 7.7 9.6 1.3 1 1 0 1 1 1 0 AAA domain PAT1 PF09770.4 CDI76395.1 - 4.2 5.4 34.8 5.7 5.0 24.1 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Spt20 PF12090.3 CDI76395.1 - 5.2 6.3 21.0 2 7.7 5.8 2.4 2 1 0 2 2 2 0 Spt20 family Ribosomal_60s PF00428.14 CDI76396.1 - 0.0063 16.8 7.9 0.24 11.8 3.5 2.7 2 0 0 2 2 2 2 60s Acidic ribosomal protein DUF2029 PF09594.5 CDI76397.1 - 1.2 8.6 15.9 0.39 10.1 1.4 2.4 1 1 2 3 3 3 0 Protein of unknown function (DUF2029) PIG-X PF08320.7 CDI76412.1 - 0.00074 18.8 1.5 0.7 9.1 0.1 2.7 3 0 0 3 3 3 2 PIG-X / PBN1 DUF2217 PF10265.4 CDI76412.1 - 8.9 4.9 16.4 0.12 11.1 5.3 1.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2217) DUF1510 PF07423.6 CDI76414.1 - 6e-06 25.7 6.3 6e-06 25.7 4.3 3.5 3 1 0 3 3 3 1 Protein of unknown function (DUF1510) DUF3675 PF12428.3 CDI76414.1 - 0.00041 20.6 6.3 0.00041 20.6 4.4 4.4 3 1 1 4 4 3 1 Protein of unknown function (DUF3675) TRAP_alpha PF03896.11 CDI76414.1 - 0.0019 17.2 0.9 0.0019 17.2 0.6 2.9 3 0 0 3 3 3 1 Translocon-associated protein (TRAP), alpha subunit SPX PF03105.14 CDI76414.1 - 0.002 17.9 4.1 0.002 17.9 2.9 2.3 1 1 0 2 2 1 1 SPX domain SpoIIIAH PF12685.2 CDI76414.1 - 0.0021 17.6 1.1 0.0021 17.6 0.8 2.9 2 1 0 2 2 2 1 SpoIIIAH-like protein Ycf1 PF05758.7 CDI76414.1 - 0.0028 15.4 15.7 0.0028 15.4 10.8 2.9 1 1 1 2 2 1 1 Ycf1 Dehydrin PF00257.14 CDI76414.1 - 0.0037 17.6 13.6 0.0037 17.6 9.4 3.0 2 2 0 2 2 1 1 Dehydrin Peptidase_S49_N PF08496.5 CDI76414.1 - 0.014 15.2 32.4 0.045 13.5 8.5 3.2 3 0 0 3 3 3 0 Peptidase family S49 N-terminal ATP-synt_8 PF00895.15 CDI76414.1 - 0.16 12.2 0.3 0.16 12.2 0.2 2.4 2 0 0 2 2 2 0 ATP synthase protein 8 ODV-E18 PF10717.4 CDI76414.1 - 4.2 6.8 8.9 0.75 9.2 0.2 2.9 2 0 0 2 2 2 0 Occlusion-derived virus envelope protein ODV-E18 RIC3 PF15361.1 CDI76414.1 - 6.2 7.0 42.5 0.41 10.8 11.4 4.1 4 0 0 4 4 4 0 Resistance to inhibitors of cholinesterase homologue 3 DUF4446 PF14584.1 CDI76414.1 - 7.2 6.4 28.2 0.064 13.0 5.2 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF4446) DUF755 PF05501.6 CDI76417.1 - 0.0027 17.7 31.1 0.0027 17.7 21.6 6.5 6 0 0 6 6 6 1 Domain of unknown function (DUF755) Activator_LAG-3 PF11498.3 CDI76417.1 - 0.0042 15.9 26.1 0.0042 15.9 18.1 4.1 4 0 0 4 4 4 2 Transcriptional activator LAG-3 SNF PF00209.13 CDI76417.1 - 0.018 13.5 3.5 0.35 9.2 1.7 2.2 2 0 0 2 2 2 0 Sodium:neurotransmitter symporter family IncA PF04156.9 CDI76417.1 - 0.3 10.6 0.0 0.015 14.9 8.9 6.0 5 1 0 5 5 5 0 IncA protein DUF3373 PF11853.3 CDI76417.1 - 4 5.8 26.0 2.5 6.5 4.4 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3373) DUF2667 PF10868.3 CDI76423.1 - 0.33 11.3 1.7 0.7 10.3 1.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2667) PGA_cap PF09587.5 CDI76423.1 - 3 7.1 8.5 0.46 9.8 2.8 2.0 2 1 0 2 2 2 0 Bacterial capsule synthesis protein PGA_cap Ribosomal_60s PF00428.14 CDI76432.1 - 0.00011 22.5 3.1 0.00011 22.5 2.2 1.5 2 0 0 2 2 1 1 60s Acidic ribosomal protein DUF2828 PF11443.3 CDI76432.1 - 0.024 12.8 2.9 0.026 12.7 2.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Suf PF05843.9 CDI76432.1 - 0.033 13.9 15.3 0.039 13.6 10.6 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Nop53 PF07767.6 CDI76432.1 - 0.035 13.1 13.8 0.039 12.9 9.6 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Cwf_Cwc_15 PF04889.7 CDI76432.1 - 0.099 12.3 11.1 0.11 12.1 7.7 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF4048 PF13257.1 CDI76432.1 - 0.11 12.0 9.1 0.14 11.8 6.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4048) FimP PF09766.4 CDI76432.1 - 0.15 11.1 17.2 0.21 10.6 12.0 1.2 1 0 0 1 1 1 0 Fms-interacting protein RAB3GAP2_N PF14655.1 CDI76432.1 - 0.22 10.5 9.0 0.3 10.0 6.2 1.2 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus DUF4207 PF13904.1 CDI76432.1 - 0.25 10.6 21.6 0.4 10.0 15.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4207) DUF4131 PF13567.1 CDI76432.1 - 0.37 10.1 5.9 0.64 9.4 4.1 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4131) SprA-related PF12118.3 CDI76432.1 - 0.44 9.8 28.9 0.57 9.4 20.0 1.2 1 0 0 1 1 1 0 SprA-related family Lin-8 PF03353.10 CDI76432.1 - 0.45 9.7 14.2 0.59 9.3 9.8 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Hid1 PF12722.2 CDI76432.1 - 0.74 7.4 7.0 0.8 7.3 4.9 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DDHD PF02862.12 CDI76432.1 - 0.81 9.4 6.9 0.96 9.2 4.8 1.2 1 0 0 1 1 1 0 DDHD domain FAM60A PF15396.1 CDI76432.1 - 0.86 9.3 5.8 1 9.0 4.0 1.2 1 0 0 1 1 1 0 Protein Family FAM60A Rtf2 PF04641.7 CDI76432.1 - 0.87 8.7 11.2 1.1 8.4 7.7 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger RR_TM4-6 PF06459.7 CDI76432.1 - 0.97 9.2 10.8 1.3 8.9 7.5 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 FLO_LFY PF01698.11 CDI76432.1 - 1.7 7.3 11.2 2 7.1 7.8 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein AAA_23 PF13476.1 CDI76432.1 - 2.6 8.2 13.4 3.4 7.9 9.3 1.2 1 0 0 1 1 1 0 AAA domain OATP PF03137.15 CDI76432.1 - 3.1 5.7 4.9 3.8 5.4 3.4 1.3 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family TMEM247 PF15444.1 CDI76432.1 - 3.2 7.5 8.1 4 7.2 5.6 1.2 1 0 0 1 1 1 0 Transmembrane protein 247 Peptidase_U57 PF05582.7 CDI76432.1 - 3.3 6.5 8.0 4.6 6.1 5.6 1.2 1 0 0 1 1 1 0 YabG peptidase U57 RskA PF10099.4 CDI76432.1 - 3.6 7.2 17.8 6 6.5 11.0 2.0 1 1 1 2 2 2 0 Anti-sigma-K factor rskA DUF1943 PF09172.6 CDI76432.1 - 4.4 6.0 8.8 1 8.1 3.5 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1943) ERF PF04404.7 CDI76432.1 - 4.4 6.8 18.3 8.6 5.8 12.7 1.5 1 0 0 1 1 1 0 ERF superfamily Tetraspannin PF00335.15 CDI76432.1 - 5.5 6.1 7.6 23 4.1 5.3 1.8 1 1 0 1 1 1 0 Tetraspanin family CDC45 PF02724.9 CDI76432.1 - 7.4 4.4 12.9 10 4.0 8.9 1.1 1 0 0 1 1 1 0 CDC45-like protein Glt_symporter PF03616.9 CDI76432.1 - 9.1 4.6 7.1 0.47 8.8 1.2 1.6 2 0 0 2 2 2 0 Sodium/glutamate symporter AAA_28 PF13521.1 CDI76433.1 - 0.017 15.1 1.6 0.017 15.1 1.1 2.0 1 1 0 2 2 2 0 AAA domain Med15 PF09606.5 CDI76433.1 - 0.071 11.2 26.1 0.081 11.1 18.1 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Activator_LAG-3 PF11498.3 CDI76433.1 - 0.074 11.7 34.8 0.11 11.2 24.1 1.3 1 0 0 1 1 1 0 Transcriptional activator LAG-3 DUF2076 PF09849.4 CDI76433.1 - 0.47 10.4 21.3 0.91 9.5 1.6 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2076) Phostensin_N PF13916.1 CDI76433.1 - 0.58 10.1 17.9 0.5 10.3 5.0 2.4 2 1 0 2 2 2 0 PP1-regulatory protein, Phostensin N-terminal APC_CDC26 PF10471.4 CDI76433.1 - 3.2 8.5 17.6 7.8 7.3 3.3 2.4 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit 1 LTP_2 PF14368.1 CDI76433.1 - 7 6.8 10.7 0.24 11.5 1.5 2.3 2 1 0 2 2 2 0 Probable lipid transfer DUF4246 PF14033.1 CDI76438.1 - 0.13 10.8 0.8 0.16 10.5 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4246) EPL1 PF10513.4 CDI76438.1 - 0.24 11.6 3.2 0.47 10.6 2.2 1.4 1 0 0 1 1 1 0 Enhancer of polycomb-like Rubis-subs-bind PF09273.6 CDI76438.1 - 4.8 7.0 6.5 4.4 7.2 3.7 1.5 2 0 0 2 2 2 0 Rubisco LSMT substrate-binding SR-25 PF10500.4 CDI76449.1 - 0.0016 17.9 15.7 0.0016 17.9 10.9 5.3 3 1 1 4 4 4 1 Nuclear RNA-splicing-associated protein DUF2761 PF10959.3 CDI76449.1 - 0.16 11.6 2.0 0.29 10.7 1.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2761) Pro_isomerase PF00160.16 CDI76449.1 - 0.3 11.2 0.0 0.3 11.2 0.0 2.3 2 1 0 2 2 2 0 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD SR-25 PF10500.4 CDI76461.1 - 0.44 9.9 48.8 1.3 8.4 23.8 2.3 1 1 2 3 3 3 0 Nuclear RNA-splicing-associated protein PAP1 PF08601.5 CDI76461.1 - 0.45 10.1 16.7 0.59 9.7 11.6 1.3 1 0 0 1 1 1 0 Transcription factor PAP1 CytochromB561_N PF09786.4 CDI76461.1 - 0.87 7.9 18.6 0.99 7.7 12.9 1.0 1 0 0 1 1 1 0 Cytochrome B561, N terminal Macoilin PF09726.4 CDI76461.1 - 1 7.5 23.0 1.6 6.9 15.9 1.3 1 0 0 1 1 1 0 Transmembrane protein Cwf_Cwc_15 PF04889.7 CDI76461.1 - 1.5 8.4 12.1 2.4 7.8 8.4 1.4 1 1 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF4207 PF13904.1 CDI76461.1 - 3.1 7.0 27.4 0.15 11.4 14.4 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4207) TFIIF_alpha PF05793.7 CDI76461.1 - 6.6 4.9 16.0 7.8 4.7 11.1 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Herpes_UL32 PF06070.6 CDI76462.1 - 0.076 11.4 1.0 0.12 10.7 0.7 1.2 1 0 0 1 1 1 0 Herpesvirus large structural phosphoprotein UL32 MCPVI PF02993.9 CDI76476.1 - 0.11 12.6 9.5 0.12 12.5 6.6 1.0 1 0 0 1 1 1 0 Minor capsid protein VI DUF444 PF04285.7 CDI76476.1 - 0.74 8.3 4.8 0.89 8.1 3.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF444) DUF4386 PF14329.1 CDI76476.1 - 1.8 8.0 15.6 2.4 7.5 10.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4386) DUF1828 PF08861.5 CDI76476.1 - 2.4 7.8 4.8 4.3 7.0 3.3 1.4 1 0 0 1 1 1 0 Domain of unknown function DUF1828 Med15 PF09606.5 CDI76476.1 - 8.7 4.4 33.8 10 4.1 23.4 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Activator_LAG-3 PF11498.3 CDI76476.1 - 9.9 4.7 28.9 11 4.6 20.1 1.0 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Med15 PF09606.5 CDI76491.1 - 4.1e-05 22.0 53.8 4.1e-05 22.0 37.3 6.2 4 3 2 6 6 6 2 ARC105 or Med15 subunit of Mediator complex non-fungal SseC PF04888.7 CDI76491.1 - 0.0011 18.4 12.8 0.0011 18.4 8.9 10.6 10 1 1 11 11 11 1 Secretion system effector C (SseC) like family TFIIA PF03153.8 CDI76494.1 - 0.00079 19.4 26.8 0.001 19.0 18.5 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit DUF4011 PF13195.1 CDI76494.1 - 0.0023 17.9 5.7 0.0029 17.6 4.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4011) TP53IP5 PF15331.1 CDI76494.1 - 0.0033 17.3 7.5 0.0047 16.8 5.2 1.3 1 0 0 1 1 1 1 Cellular tumour antigen p53-inducible 5 DDHD PF02862.12 CDI76494.1 - 0.0045 16.8 4.9 0.0049 16.6 3.4 1.1 1 0 0 1 1 1 1 DDHD domain DUF912 PF06024.7 CDI76494.1 - 0.036 14.1 6.7 0.052 13.5 1.7 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Med15 PF09606.5 CDI76494.1 - 0.048 11.8 53.0 0.064 11.4 36.7 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal SPX PF03105.14 CDI76494.1 - 0.05 13.3 4.7 0.066 12.9 3.3 1.2 1 0 0 1 1 1 0 SPX domain PAT1 PF09770.4 CDI76494.1 - 0.064 11.4 35.6 0.086 11.0 24.7 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF4207 PF13904.1 CDI76494.1 - 0.076 12.3 26.2 0.026 13.9 6.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4207) DUF1764 PF08576.5 CDI76494.1 - 0.082 13.6 11.0 0.96 10.2 4.1 2.2 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF1764) FimP PF09766.4 CDI76494.1 - 0.084 11.9 23.3 0.068 12.2 10.0 2.1 2 0 0 2 2 2 0 Fms-interacting protein BNR_3 PF13859.1 CDI76494.1 - 0.13 11.3 4.4 0.15 11.1 3.0 1.1 1 0 0 1 1 1 0 BNR repeat-like domain DUF4484 PF14831.1 CDI76494.1 - 0.16 12.0 3.4 0.23 11.5 2.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4484) Gti1_Pac2 PF09729.4 CDI76494.1 - 0.17 11.7 3.2 0.25 11.1 2.2 1.3 1 0 0 1 1 1 0 Gti1/Pac2 family Peptidase_M56 PF05569.6 CDI76494.1 - 0.31 9.9 7.7 0.38 9.6 5.4 1.1 1 0 0 1 1 1 0 BlaR1 peptidase M56 U1snRNP70_N PF12220.3 CDI76494.1 - 0.36 11.1 18.7 0.78 10.1 6.3 2.2 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal Herpes_UL87 PF03043.9 CDI76494.1 - 0.64 8.3 7.7 0.71 8.1 5.3 1.1 1 0 0 1 1 1 0 Herpesvirus UL87 family DUF3853 PF12964.2 CDI76494.1 - 1.5 8.7 6.5 1.8 8.4 1.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3853) DUF913 PF06025.7 CDI76494.1 - 2.3 6.8 14.0 0.095 11.4 5.3 1.7 1 1 1 2 2 2 0 Domain of Unknown Function (DUF913) DUF2722 PF10846.3 CDI76494.1 - 3.5 6.5 19.6 2.1 7.2 7.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) SprA-related PF12118.3 CDI76494.1 - 5.2 6.3 44.9 0.25 10.6 18.6 2.1 2 0 0 2 2 2 0 SprA-related family CIAPIN1 PF05093.8 CDI76494.1 - 5.8 7.0 9.7 0.72 9.9 1.6 2.2 2 0 0 2 2 2 0 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis ATAD4 PF15321.1 CDI76494.1 - 5.8 7.9 12.4 1.4 10.0 2.5 2.2 2 0 0 2 2 2 0 ATPase family AAA domain containing 4 MDFI PF15316.1 CDI76494.1 - 6.6 6.6 13.0 0.34 10.8 5.0 1.7 1 1 1 2 2 2 0 MyoD family inhibitor DUF4355 PF14265.1 CDI76494.1 - 6.8 6.6 23.4 0.38 10.7 6.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4355) DUF3295 PF11702.3 CDI76494.1 - 7.1 5.4 13.1 8.5 5.2 9.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) CD20 PF04103.10 CDI76494.1 - 9.2 6.1 8.2 41 4.0 5.7 2.0 1 1 0 1 1 1 0 CD20-like family DHHW PF14286.1 CDI76494.1 - 9.8 5.3 13.7 14 4.8 9.5 1.3 1 1 0 1 1 1 0 DHHW protein DUF788 PF05620.6 CDI76507.1 - 0.017 14.9 2.1 0.017 14.9 1.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF788) EphA2_TM PF14575.1 CDI76507.1 - 0.15 12.4 2.4 0.23 11.8 0.1 2.3 1 1 1 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Salp15 PF12115.3 CDI76507.1 - 0.59 10.3 4.3 1.2 9.3 3.0 1.4 1 0 0 1 1 1 0 Salivary protein of 15kDa inhibits CD4+ T cell activation Hid1 PF12722.2 CDI76507.1 - 3.4 5.2 9.7 3.9 5.0 6.7 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Phostensin_N PF13916.1 CDI76507.1 - 4.1 7.4 19.7 0.24 11.4 2.3 3.3 3 0 0 3 3 3 0 PP1-regulatory protein, Phostensin N-terminal ExbD PF02472.11 CDI76507.1 - 6.1 6.8 9.5 1.4 8.8 4.0 1.9 2 0 0 2 2 2 0 Biopolymer transport protein ExbD/TolR Glycos_transf_1 PF00534.15 CDI76521.1 - 4.5e-29 101.0 0.0 5.5e-27 94.2 0.0 3.1 2 1 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 CDI76521.1 - 9.1e-12 45.3 3.8 7.8e-10 39.1 0.8 3.9 3 1 0 3 3 3 1 Glycosyl transferase 4-like domain Alpha-amylase_C PF02806.13 CDI76521.1 - 5.5e-11 42.4 0.0 1.4e-10 41.1 0.0 1.7 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain Glyco_transf_4 PF13439.1 CDI76521.1 - 1.2e-10 41.4 1.1 5.4e-07 29.4 0.0 2.5 1 1 1 2 2 2 2 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.1 CDI76521.1 - 1.3e-10 41.5 0.0 3.3e-10 40.2 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Alpha-amylase PF00128.19 CDI76521.1 - 2.4e-10 40.3 0.0 5.2e-07 29.3 0.0 2.7 2 1 0 3 3 3 2 Alpha amylase, catalytic domain CBM_48 PF02922.13 CDI76521.1 - 1.3e-09 37.9 0.1 4.4e-08 33.0 0.0 2.4 1 1 0 2 2 2 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Glyco_trans_1_2 PF13524.1 CDI76521.1 - 0.00028 21.0 0.0 0.00082 19.5 0.0 1.8 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_5 PF08323.6 CDI76521.1 - 0.002 17.6 1.0 0.049 13.1 0.1 2.6 2 1 1 3 3 3 1 Starch synthase catalytic domain Glyco_hydro_31 PF01055.21 CDI76521.1 - 0.045 12.5 0.0 0.073 11.8 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolases family 31 TTL PF03133.10 CDI76522.1 - 0.00075 18.5 0.1 0.0012 17.8 0.0 1.4 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family NapB PF03892.9 CDI76522.1 - 0.0056 16.3 1.5 0.013 15.1 1.0 1.6 1 0 0 1 1 1 1 Nitrate reductase cytochrome c-type subunit (NapB) FANCI_HD1 PF14679.1 CDI76522.1 - 0.02 14.6 0.3 0.035 13.8 0.2 1.4 1 0 0 1 1 1 0 FANCI helical domain 1 zf-CCCH_2 PF14608.1 CDI76523.1 - 2.2e-08 33.7 31.0 0.0029 17.5 4.6 3.5 3 0 0 3 3 3 3 Zinc finger C-x8-C-x5-C-x3-H type zf-CCCH PF00642.19 CDI76523.1 - 0.0095 15.5 0.7 0.0095 15.5 0.5 4.1 3 1 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCHH PF10283.4 CDI76523.1 - 0.17 11.7 16.3 1.8 8.4 0.9 3.7 3 0 0 3 3 3 0 Zinc-finger (CX5CX6HX5H) motif HlyD_2 PF12700.2 CDI76523.1 - 2.8 7.0 12.0 5.6 6.0 8.3 1.4 1 0 0 1 1 1 0 HlyD family secretion protein RAP1 PF07218.6 CDI76538.1 - 2.4 6.1 11.9 2.9 5.8 8.3 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Peptidase_C2 PF00648.16 CDI76548.1 - 0.17 10.8 4.0 0.17 10.8 2.7 1.0 1 0 0 1 1 1 0 Calpain family cysteine protease PSP1 PF04468.7 CDI76548.1 - 0.23 11.4 3.9 0.38 10.7 2.7 1.3 1 0 0 1 1 1 0 PSP1 C-terminal conserved region Alpha-amylase PF00128.19 CDI76548.1 - 0.29 10.4 7.1 0.32 10.3 4.9 1.0 1 0 0 1 1 1 0 Alpha amylase, catalytic domain MACPF PF01823.14 CDI76548.1 - 0.62 9.7 9.1 0.75 9.4 6.3 1.1 1 0 0 1 1 1 0 MAC/Perforin domain BBS2_C PF14782.1 CDI76548.1 - 0.9 8.0 12.9 0.94 7.9 8.9 1.0 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, C-terminal YniB PF14002.1 CDI76548.1 - 1.1 8.6 5.2 1.5 8.2 3.6 1.2 1 0 0 1 1 1 0 YniB-like protein CemA PF03040.9 CDI76548.1 - 1.3 8.6 4.4 1.5 8.3 3.1 1.1 1 0 0 1 1 1 0 CemA family DUF3573 PF12097.3 CDI76548.1 - 1.5 7.3 17.6 1.6 7.2 12.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) Chorion_2 PF03964.10 CDI76548.1 - 2.1 8.9 8.5 3.2 8.3 5.9 1.4 1 1 0 1 1 1 0 Chorion family 2 DUF3523 PF12037.3 CDI76548.1 - 2.9 6.7 22.4 3.3 6.6 15.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3523) Herpes_pp85 PF04637.7 CDI76548.1 - 4 5.6 14.1 4.5 5.4 9.8 1.0 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) Pep_M12B_propep PF01562.14 CDI76548.1 - 4.2 7.1 8.3 5.1 6.8 5.7 1.3 1 1 0 1 1 1 0 Reprolysin family propeptide Membralin PF09746.4 CDI76548.1 - 5.6 5.9 8.4 5.2 6.0 5.8 1.1 1 0 0 1 1 1 0 Tumour-associated protein DUF2368 PF10166.4 CDI76548.1 - 5.8 6.5 14.8 7.9 6.1 10.2 1.3 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2368) Baculo_p24 PF05073.7 CDI76548.1 - 6.4 6.2 10.9 8.2 5.9 7.6 1.1 1 0 0 1 1 1 0 Baculovirus P24 capsid protein HGTP_anticodon2 PF12745.2 CDI76548.1 - 7 5.7 14.0 8.8 5.3 9.7 1.0 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs Borrelia_P83 PF05262.6 CDI76548.1 - 7.3 4.7 16.8 7.5 4.6 11.6 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein 5_nucleotid PF05761.9 CDI76548.1 - 7.4 4.9 9.1 7.9 4.8 6.3 1.1 1 0 0 1 1 1 0 5' nucleotidase family Ribosomal_60s PF00428.14 CDI76574.1 - 0.0069 16.7 33.9 0.25 11.7 2.3 3.6 3 0 0 3 3 3 3 60s Acidic ribosomal protein Shadoo PF14999.1 CDI76574.1 - 0.021 14.6 1.0 0.021 14.6 0.7 3.3 3 0 0 3 3 3 0 Shadow of prion protein, neuroprotective Herpes_UL87 PF03043.9 CDI76574.1 - 0.78 8.0 21.6 0.85 7.9 14.0 1.6 1 1 0 1 1 1 0 Herpesvirus UL87 family SR-25 PF10500.4 CDI76574.1 - 1.6 8.1 54.0 2.1 7.7 6.2 3.2 2 1 0 3 3 3 0 Nuclear RNA-splicing-associated protein FimP PF09766.4 CDI76577.1 - 0.11 11.5 10.5 0.098 11.7 7.3 1.0 1 0 0 1 1 1 0 Fms-interacting protein CD20 PF04103.10 CDI76577.1 - 0.34 10.8 2.4 0.44 10.4 1.7 1.2 1 0 0 1 1 1 0 CD20-like family Spt20 PF12090.3 CDI76577.1 - 0.46 9.8 8.4 0.4 9.9 5.8 1.1 1 0 0 1 1 1 0 Spt20 family Activator_LAG-3 PF11498.3 CDI76577.1 - 1.5 7.4 28.0 1.5 7.4 19.4 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 CbiD PF01888.12 CDI76577.1 - 2.1 7.2 7.0 2.5 7.0 4.9 1.1 1 0 0 1 1 1 0 CbiD RAB3GAP2_N PF14655.1 CDI76577.1 - 2.6 6.9 10.1 2.5 6.9 7.0 1.1 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus DUF2232 PF09991.4 CDI76577.1 - 3.1 6.7 5.1 3.2 6.6 3.6 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) Aminotran_1_2 PF00155.16 CDI76577.1 - 5.5 5.8 10.2 6 5.7 7.0 1.0 1 0 0 1 1 1 0 Aminotransferase class I and II Suf PF05843.9 CDI76577.1 - 5.9 6.5 13.2 5.6 6.6 9.1 1.0 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) CD99L2 PF12301.3 CDI76577.1 - 6.2 6.4 9.5 7.6 6.1 6.6 1.2 1 0 0 1 1 1 0 CD99 antigen like protein 2 Med15 PF09606.5 CDI76577.1 - 6.4 4.8 33.6 6.7 4.7 23.3 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal E_Pc_C PF06752.7 CDI76578.1 - 2.1e-05 24.1 12.4 2.1e-05 24.1 8.6 12.1 7 3 1 9 9 9 1 Enhancer of Polycomb C-terminus IspD PF01128.14 CDI76584.1 - 2.8e-13 49.9 23.9 5.9e-12 45.5 3.5 3.8 3 1 0 3 3 3 2 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase IncA PF04156.9 CDI76584.1 - 0.0048 16.5 1.1 0.0048 16.5 0.8 6.0 4 3 0 4 4 4 1 IncA protein TMF_TATA_bd PF12325.3 CDI76597.1 - 0.0029 17.3 23.6 0.0029 17.3 16.3 2.9 1 1 2 3 3 3 1 TATA element modulatory factor 1 TATA binding IncA PF04156.9 CDI76597.1 - 0.031 13.8 63.4 0.04 13.4 13.6 2.1 1 1 1 2 2 2 0 IncA protein DUF3407 PF11887.3 CDI76597.1 - 0.046 13.0 3.2 0.029 13.6 0.7 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3407) Sigma_1_2 PF03084.9 CDI76597.1 - 3.7 6.0 6.4 5.3 5.5 4.5 1.3 1 0 0 1 1 1 0 Reoviral Sigma1/Sigma2 family DC_STAMP PF07782.8 CDI76597.1 - 7.9 6.0 8.5 0.48 10.0 0.0 2.2 2 0 0 2 2 2 0 DC-STAMP-like protein Tsg PF04668.7 CDI76599.1 - 0.1 12.8 0.0 0.11 12.6 0.0 1.1 1 0 0 1 1 1 0 Twisted gastrulation (Tsg) protein conserved region OPT PF03169.10 CDI76602.1 - 9.7 4.4 7.5 1.7 6.9 2.5 1.7 1 1 1 2 2 2 0 OPT oligopeptide transporter protein Methyltransf_15 PF09445.5 CDI76606.1 - 1.7e-30 105.7 0.0 2.8e-30 105.0 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_26 PF13659.1 CDI76606.1 - 2.3e-05 24.4 0.9 7e-05 22.8 0.1 2.2 2 1 0 2 2 2 1 Methyltransferase domain Met_10 PF02475.11 CDI76606.1 - 0.00048 19.7 0.0 0.00094 18.8 0.0 1.4 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_18 PF12847.2 CDI76606.1 - 0.037 14.6 0.0 0.11 13.0 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain HSP90 PF00183.13 CDI76607.1 - 1.2e-79 268.1 0.0 4.2e-77 259.7 0.0 2.2 1 1 1 2 2 2 2 Hsp90 protein HATPase_c_3 PF13589.1 CDI76607.1 - 1.1e-12 47.8 0.0 1.9e-12 46.9 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 CDI76607.1 - 1.4e-07 31.2 0.0 2.9e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF2183 PF09949.4 CDI76607.1 - 0.0045 16.9 0.2 1.9 8.4 0.0 2.6 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2183) CBP4 PF07960.6 CDI76607.1 - 0.086 12.4 3.8 0.23 11.0 2.7 1.7 1 0 0 1 1 1 0 CBP4 OmpH PF03938.9 CDI76614.1 - 0.0039 17.1 55.6 0.0039 17.1 38.6 4.0 3 1 0 3 3 3 1 Outer membrane protein (OmpH-like) MARCKS PF02063.12 CDI76622.1 - 0.093 12.5 56.6 0.23 11.2 13.2 2.2 2 0 0 2 2 2 0 MARCKS family Zip PF02535.17 CDI76622.1 - 2.2 7.2 26.5 0.28 10.1 4.1 2.4 2 1 0 2 2 2 0 ZIP Zinc transporter Vfa1 PF08432.5 CDI76622.1 - 2.6 8.0 60.4 0.46 10.4 7.6 2.1 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 OPT PF03169.10 CDI76622.1 - 8.3 4.6 10.2 3.7 5.8 0.5 2.2 2 0 0 2 2 2 0 OPT oligopeptide transporter protein UPF0020 PF01170.13 CDI76632.1 - 1.9e-06 27.5 0.1 4.3e-06 26.4 0.0 1.6 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Activator_LAG-3 PF11498.3 CDI76632.1 - 0.004 15.9 0.2 0.004 15.9 0.1 4.1 4 0 0 4 4 4 1 Transcriptional activator LAG-3 Methyltransf_26 PF13659.1 CDI76632.1 - 0.036 14.1 0.1 0.036 14.1 0.1 4.6 3 2 0 3 3 3 0 Methyltransferase domain DUF2217 PF10265.4 CDI76632.1 - 2.1 7.0 6.5 4.9 5.7 4.5 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) DUF2215 PF10225.4 CDI76632.1 - 2.3 7.6 7.3 2.4 7.5 1.3 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2215) Reo_sigmaC PF04582.7 CDI76636.1 - 0.00029 20.1 7.6 0.00029 20.1 5.2 3.4 1 1 2 3 3 3 2 Reovirus sigma C capsid protein Sporozoite_P67 PF05642.6 CDI76650.1 - 0.00022 19.2 7.9 0.00022 19.2 5.5 3.5 3 1 1 4 4 4 1 Sporozoite P67 surface antigen Ribosomal_60s PF00428.14 CDI76650.1 - 0.0068 16.7 5.8 0.0068 16.7 4.0 8.6 6 1 2 8 8 8 2 60s Acidic ribosomal protein WD40 PF00400.27 CDI76650.1 - 0.021 14.7 0.0 5.5 7.0 0.0 3.8 4 0 0 4 4 4 0 WD domain, G-beta repeat YfhO PF09586.5 CDI76650.1 - 7.7 4.3 26.5 3.5 5.5 0.1 2.2 2 0 0 2 2 2 0 Bacterial membrane protein YfhO PAXIP1_C PF15364.1 CDI76655.1 - 0.00082 19.2 2.8 0.0013 18.6 2.0 1.3 1 0 0 1 1 1 1 PAXIP1-associated-protein-1 C term PTIP binding protein Suf PF05843.9 CDI76655.1 - 0.0025 17.5 4.6 0.0025 17.5 3.2 1.2 1 0 0 1 1 1 1 Suppressor of forked protein (Suf) BAF1_ABF1 PF04684.8 CDI76655.1 - 0.0058 15.5 22.2 0.007 15.2 15.4 1.2 1 0 0 1 1 1 1 BAF1 / ABF1 chromatin reorganising factor SAM_adeno_trans PF01887.11 CDI76655.1 - 0.0063 15.5 0.1 0.0085 15.1 0.0 1.1 1 0 0 1 1 1 1 S-adenosyl-l-methionine hydroxide adenosyltransferase FimP PF09766.4 CDI76655.1 - 0.024 13.7 10.7 0.03 13.4 7.4 1.2 1 0 0 1 1 1 0 Fms-interacting protein CENP-L PF13092.1 CDI76655.1 - 0.026 14.2 2.0 0.15 11.8 1.7 1.7 2 0 0 2 2 2 0 Kinetochore complex Sim4 subunit Fta1 DUF3897 PF13036.1 CDI76655.1 - 0.036 13.6 10.8 0.039 13.5 7.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3897) Gag_spuma PF03276.9 CDI76655.1 - 0.037 12.3 10.8 0.047 12.0 7.5 1.1 1 0 0 1 1 1 0 Spumavirus gag protein Toxin_R_bind_C PF07951.7 CDI76655.1 - 0.12 12.0 8.2 0.14 11.7 5.7 1.2 1 0 0 1 1 1 0 Clostridium neurotoxin, C-terminal receptor binding Zip PF02535.17 CDI76655.1 - 0.14 11.1 0.6 0.14 11.1 0.4 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Serinc PF03348.10 CDI76655.1 - 0.29 9.7 6.0 0.35 9.5 4.2 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) WASH-7_C PF14746.1 CDI76655.1 - 0.31 10.6 5.8 0.56 9.7 4.0 1.5 1 0 0 1 1 1 0 WASH complex subunit 7, C-terminal SHR3_chaperone PF08229.6 CDI76655.1 - 0.43 9.4 5.5 0.81 8.6 3.8 1.5 1 0 0 1 1 1 0 ER membrane protein SH3 DUF775 PF05603.7 CDI76655.1 - 1.2 8.6 13.1 0.7 9.3 8.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF775) Conotoxin PF02950.12 CDI76655.1 - 3.1 8.6 5.6 6.5 7.6 3.9 1.5 1 0 0 1 1 1 0 Conotoxin EphA2_TM PF14575.1 CDI76655.1 - 6.1 7.3 7.0 0.98 9.8 1.8 2.0 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain SDH_alpha PF03313.10 CDI76656.1 - 0.0092 15.0 10.2 0.012 14.6 7.1 1.2 1 0 0 1 1 1 1 Serine dehydratase alpha chain Med15 PF09606.5 CDI76656.1 - 0.088 10.9 61.5 0.13 10.4 42.7 1.3 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal FlxA PF14282.1 CDI76656.1 - 0.13 12.2 77.3 0.025 14.5 50.2 2.0 2 0 0 2 2 2 0 FlxA-like protein SR-25 PF10500.4 CDI76656.1 - 0.19 11.2 49.2 9.4e+02 -1.0 34.1 2.4 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein ABC2_membrane_2 PF12679.2 CDI76656.1 - 0.46 9.2 3.2 0.62 8.8 2.2 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein eIF-3_zeta PF05091.7 CDI76656.1 - 0.74 8.3 28.4 0.83 8.2 19.7 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF1501 PF07394.7 CDI76656.1 - 1.6 7.4 27.1 2.1 7.1 18.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) DUF342 PF03961.8 CDI76656.1 - 2.7 6.2 15.0 3 6.1 10.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) PAT1 PF09770.4 CDI76656.1 - 2.9 6.0 55.2 3.6 5.7 38.3 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 V_ATPase_I PF01496.14 CDI76656.1 - 3.2 5.5 16.4 3.6 5.3 11.4 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CAF-1_p150 PF11600.3 CDI76656.1 - 4 6.7 45.9 1.1 8.5 29.8 1.5 1 1 1 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF3584 PF12128.3 CDI76656.1 - 5.6 4.1 43.5 6 4.0 30.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Utp14 PF04615.8 CDI76656.1 - 8.7 4.3 39.2 10 4.1 27.1 1.0 1 0 0 1 1 1 0 Utp14 protein SOBP PF15279.1 CDI76656.1 - 8.9 6.5 35.3 11 6.2 24.4 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein Band_3_cyto PF07565.8 CDI76667.1 - 0.041 13.3 34.9 0.37 10.2 17.5 2.1 2 0 0 2 2 2 0 Band 3 cytoplasmic domain PAT1 PF09770.4 CDI76667.1 - 0.21 9.7 94.5 0.26 9.4 65.5 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 HI0933_like PF03486.9 CDI76668.1 - 0.013 14.0 5.4 0.014 13.9 3.8 1.0 1 0 0 1 1 1 0 HI0933-like protein Inositol_P PF00459.20 CDI76668.1 - 0.021 14.1 5.2 0.024 13.9 3.6 1.0 1 0 0 1 1 1 0 Inositol monophosphatase family AAA_32 PF13654.1 CDI76668.1 - 0.043 12.4 7.3 0.047 12.3 5.1 1.0 1 0 0 1 1 1 0 AAA domain DUF3662 PF12401.3 CDI76668.1 - 0.052 13.7 7.5 2.1 8.5 5.2 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF2662) DUF445 PF04286.7 CDI76668.1 - 0.093 12.2 9.8 0.11 12.0 6.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF445) Mmp37 PF09139.6 CDI76668.1 - 0.1 11.6 4.3 0.1 11.5 3.0 1.0 1 0 0 1 1 1 0 Mitochondrial matrix Mmp37 Ofd1_CTDD PF10637.4 CDI76668.1 - 0.1 11.6 8.8 0.11 11.6 6.1 1.0 1 0 0 1 1 1 0 Oxoglutarate and iron-dependent oxygenase degradation C-term OmpH PF03938.9 CDI76668.1 - 0.13 12.2 28.8 0.16 11.9 19.9 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF2203 PF09969.4 CDI76668.1 - 0.15 12.2 5.7 0.19 11.9 4.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) DUF4127 PF13552.1 CDI76668.1 - 0.17 10.2 5.3 0.2 10.0 3.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4127) DUF668 PF05003.7 CDI76668.1 - 0.23 11.6 6.3 0.31 11.2 4.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF668) DUF45 PF01863.12 CDI76668.1 - 0.24 11.1 6.1 0.31 10.7 4.2 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF45 CHAD PF05235.9 CDI76668.1 - 0.27 10.8 9.8 0.27 10.7 6.8 1.0 1 0 0 1 1 1 0 CHAD domain DUF3878 PF12994.2 CDI76668.1 - 0.33 10.0 4.0 0.41 9.7 2.8 1.0 1 0 0 1 1 1 0 Domain of unknown function, E. rectale Gene description (DUF3878) PIG-S PF10510.4 CDI76668.1 - 0.34 9.5 7.3 0.42 9.2 5.1 1.2 1 0 0 1 1 1 0 Phosphatidylinositol-glycan biosynthesis class S protein DUF2743 PF10899.3 CDI76668.1 - 0.41 9.9 3.0 0.48 9.7 2.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2743) CotH PF08757.6 CDI76668.1 - 0.47 9.6 3.9 0.56 9.4 2.7 1.0 1 0 0 1 1 1 0 CotH protein WASH-7_mid PF14744.1 CDI76668.1 - 0.5 9.1 5.6 0.6 8.9 3.8 1.0 1 0 0 1 1 1 0 WASH complex subunit 7 DUF4355 PF14265.1 CDI76668.1 - 0.56 10.1 19.7 1 9.3 13.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4355) KGK PF08872.5 CDI76668.1 - 0.58 10.3 4.1 10 6.2 2.9 2.0 1 1 0 1 1 1 0 KGK domain DUF2924 PF11149.3 CDI76668.1 - 0.7 9.9 7.7 0.83 9.6 5.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2924) Spore_II_R PF09551.5 CDI76668.1 - 0.71 9.8 9.6 0.88 9.6 6.7 1.1 1 0 0 1 1 1 0 Stage II sporulation protein R (spore_II_R) Band_7_1 PF13421.1 CDI76668.1 - 1.1 8.7 5.6 1.4 8.4 3.9 1.1 1 0 0 1 1 1 0 SPFH domain-Band 7 family MRP-L46 PF11788.3 CDI76668.1 - 1.1 9.9 7.2 1.8 9.2 5.0 1.4 1 0 0 1 1 1 0 39S mitochondrial ribosomal protein L46 RED_N PF07808.8 CDI76668.1 - 1.5 7.9 13.3 1.4 8.0 9.2 1.1 1 0 0 1 1 1 0 RED-like protein N-terminal region Exonuc_VII_L PF02601.10 CDI76668.1 - 1.7 7.7 7.8 1.9 7.6 5.4 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF1690 PF07956.6 CDI76668.1 - 1.7 8.5 17.3 2.3 8.1 12.0 1.1 1 0 0 1 1 1 0 Protein of Unknown function (DUF1690) AMP-binding_C_2 PF14535.1 CDI76668.1 - 1.9 8.6 6.3 8.7 6.4 4.4 1.9 1 1 0 1 1 1 0 AMP-binding enzyme C-terminal domain DUF330 PF03886.8 CDI76668.1 - 1.9 7.8 15.1 7.6 5.8 3.7 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF330) Vps39_2 PF10367.4 CDI76668.1 - 2 8.6 7.5 2.6 8.2 5.2 1.3 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 2 TPD PF14811.1 CDI76668.1 - 2.8 7.4 8.3 4.6 6.7 5.7 1.4 1 1 0 1 1 1 0 Protein of unknown function TPD sequence-motif GbpC PF08363.5 CDI76668.1 - 3 7.0 5.2 3.5 6.7 3.6 1.0 1 0 0 1 1 1 0 Glucan-binding protein C HlyD_2 PF12700.2 CDI76668.1 - 3.4 6.7 9.8 3.3 6.7 6.8 1.0 1 0 0 1 1 1 0 HlyD family secretion protein DUF3646 PF12362.3 CDI76668.1 - 4.1 7.3 11.7 66 3.4 8.1 2.0 1 1 0 1 1 1 0 DNA polymerase III gamma and tau subunits C terminal FliL PF03748.9 CDI76668.1 - 4.4 7.3 17.6 16 5.5 12.2 1.7 1 1 0 1 1 1 0 Flagellar basal body-associated protein FliL DUF3313 PF11769.3 CDI76668.1 - 5.3 6.3 20.5 8.9 5.6 6.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3313) DUF3683 PF12447.3 CDI76668.1 - 5.4 6.8 7.4 7.2 6.4 5.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3683) DUF1800 PF08811.6 CDI76668.1 - 5.8 5.7 11.6 6.8 5.5 8.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1800) DDE_Tnp_IS66 PF03050.9 CDI76668.1 - 6 6.0 9.2 7.1 5.7 6.4 1.1 1 0 0 1 1 1 0 Transposase IS66 family FHIPEP PF00771.15 CDI76668.1 - 6.6 4.9 12.2 7.6 4.7 8.5 1.0 1 0 0 1 1 1 0 FHIPEP family MCPVI PF02993.9 CDI76668.1 - 7 6.7 11.6 8.5 6.4 8.0 1.2 1 0 0 1 1 1 0 Minor capsid protein VI FUSC PF04632.7 CDI76668.1 - 7.1 4.9 7.0 6.7 5.0 4.9 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family Rad50_zn_hook PF04423.9 CDI76668.1 - 8.8 5.8 11.5 3.3e+03 -2.4 8.0 2.6 1 1 0 1 1 1 0 Rad50 zinc hook motif Spore_coat_CotO PF14153.1 CDI76669.1 - 0.0043 16.5 12.0 0.0043 16.5 8.3 4.4 3 1 1 4 4 4 1 Spore coat protein CotO Nop53 PF07767.6 CDI76671.1 - 1.1e-14 54.2 16.0 1.1e-14 54.2 11.1 9.4 5 3 4 9 9 9 1 Nop53 (60S ribosomal biogenesis) La PF05383.12 CDI76671.1 - 7.3e-08 32.0 0.0 0.00012 21.8 0.0 2.5 2 0 0 2 2 2 2 La domain PTEN_C2 PF10409.4 CDI76678.1 - 0.023 14.4 0.1 0.023 14.4 0.1 3.0 2 1 0 2 2 2 0 C2 domain of PTEN tumour-suppressor protein DDHD PF02862.12 CDI76678.1 - 0.21 11.3 17.6 0.67 9.7 8.6 2.1 2 0 0 2 2 2 0 DDHD domain Spore_coat_CotO PF14153.1 CDI76678.1 - 6.2 6.2 33.8 3.5 7.0 16.5 2.3 2 0 0 2 2 2 0 Spore coat protein CotO SpoVR PF04293.8 CDI76678.1 - 8.1 4.6 27.4 1.3 7.3 12.1 2.1 2 0 0 2 2 2 0 SpoVR like protein Glycos_transf_4 PF00953.16 CDI76686.1 - 8.1e-08 32.2 0.3 8.1e-08 32.2 0.2 1.7 2 0 0 2 2 2 1 Glycosyl transferase family 4 SR-25 PF10500.4 CDI76686.1 - 0.00034 20.1 8.1 0.00034 20.1 5.6 1.7 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein Pex14_N PF04695.8 CDI76686.1 - 0.00046 20.2 31.1 0.042 13.8 13.4 2.2 2 0 0 2 2 2 2 Peroxisomal membrane anchor protein (Pex14p) conserved region FimP PF09766.4 CDI76686.1 - 0.00075 18.6 25.0 0.032 13.3 13.9 2.1 2 0 0 2 2 2 2 Fms-interacting protein DUF3722 PF12519.3 CDI76686.1 - 0.0033 16.7 9.3 0.0033 16.7 6.4 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF3722) PAT1 PF09770.4 CDI76686.1 - 0.0034 15.7 51.9 0.0046 15.2 35.9 1.0 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 NARP1 PF12569.3 CDI76686.1 - 0.0065 15.2 11.8 0.0065 15.2 8.2 1.7 1 1 0 2 2 2 1 NMDA receptor-regulated protein 1 Raftlin PF15250.1 CDI76686.1 - 0.014 13.9 16.0 0.017 13.6 11.1 1.1 1 0 0 1 1 1 0 Raftlin MRP-S31 PF15433.1 CDI76686.1 - 0.019 14.4 25.3 0.024 14.0 17.6 1.1 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 Kei1 PF08552.6 CDI76686.1 - 0.02 14.5 11.9 0.17 11.5 2.7 2.2 2 0 0 2 2 2 0 Inositolphosphorylceramide synthase subunit Kei1 Ribosomal_60s PF00428.14 CDI76686.1 - 0.029 14.7 11.0 0.3 11.5 1.8 2.3 2 0 0 2 2 2 0 60s Acidic ribosomal protein Zip PF02535.17 CDI76686.1 - 0.11 11.4 6.5 0.17 10.8 4.5 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter DUF1682 PF07946.9 CDI76686.1 - 0.17 10.6 17.9 0.23 10.2 12.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) DUF3801 PF12687.2 CDI76686.1 - 0.43 10.1 19.4 0.76 9.3 13.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3801) 2OG-FeII_Oxy_5 PF13759.1 CDI76686.1 - 0.44 10.8 10.6 4.2 7.7 5.0 2.1 2 0 0 2 2 2 0 Putative 2OG-Fe(II) oxygenase Nha1_C PF08619.5 CDI76686.1 - 0.55 9.4 15.8 0.75 9.0 10.9 1.1 1 0 0 1 1 1 0 Alkali metal cation/H+ antiporter Nha1 C terminus SpoVR PF04293.8 CDI76686.1 - 1 7.6 22.0 0.044 12.1 10.7 1.7 1 1 1 2 2 2 0 SpoVR like protein NifQ PF04891.7 CDI76686.1 - 1.1 9.3 17.0 0.12 12.5 2.5 2.2 2 0 0 2 2 2 0 NifQ AIF_C PF14721.1 CDI76686.1 - 1.8 8.7 15.8 0.61 10.3 5.6 2.2 2 0 0 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term DUF4446 PF14584.1 CDI76686.1 - 2.1 8.1 13.6 6.2 6.6 6.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) PBP1_TM PF14812.1 CDI76686.1 - 2.6 8.4 5.3 0.58 10.4 1.1 1.7 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF4512 PF14975.1 CDI76686.1 - 3.1 8.6 12.2 32 5.4 5.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4512) DUF940 PF06082.6 CDI76686.1 - 3.3 6.1 15.3 4.2 5.8 10.6 1.1 1 0 0 1 1 1 0 Bacterial putative lipoprotein (DUF940) Pox_P21 PF05313.7 CDI76686.1 - 5.8 6.1 9.3 0.076 12.2 0.5 2.1 1 1 1 2 2 2 0 Poxvirus P21 membrane protein SID-1_RNA_chan PF13965.1 CDI76686.1 - 6 4.9 11.7 8.1 4.4 8.1 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Gastrin PF00918.12 CDI76686.1 - 8 7.3 30.6 2.2 9.1 11.8 2.3 2 0 0 2 2 2 0 Gastrin/cholecystokinin family FNIP_N PF14636.1 CDI76686.1 - 9.3 6.7 23.1 2.2 8.7 10.8 2.1 2 0 0 2 2 2 0 Folliculin-interacting protein N-terminus SPT16 PF08644.6 CDI76686.1 - 9.3 6.0 16.6 4.3 7.1 0.2 2.2 2 0 0 2 2 2 0 FACT complex subunit (SPT16/CDC68) CD20 PF04103.10 CDI76686.1 - 9.8 6.0 15.5 0.17 11.8 3.4 2.7 1 1 1 2 2 2 0 CD20-like family EphA2_TM PF14575.1 CDI76702.1 - 0.035 14.5 13.8 0.76 10.2 2.0 2.2 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain DDHD PF02862.12 CDI76702.1 - 0.17 11.6 14.7 0.22 11.3 10.2 1.2 1 0 0 1 1 1 0 DDHD domain Pan_kinase PF03309.9 CDI76702.1 - 0.4 10.1 8.2 0.49 9.8 5.7 1.1 1 0 0 1 1 1 0 Type III pantothenate kinase Laps PF10169.4 CDI76702.1 - 0.47 10.7 16.2 0.6 10.3 11.3 1.1 1 0 0 1 1 1 0 Learning-associated protein Plasmodium_Vir PF05795.6 CDI76702.1 - 2.5 7.2 5.6 3.4 6.7 3.9 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein DUF3474 PF11960.3 CDI76702.1 - 2.6 8.0 8.9 3.3 7.7 6.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3474) BNR_3 PF13859.1 CDI76702.1 - 3.1 6.7 8.6 4 6.4 6.0 1.2 1 0 0 1 1 1 0 BNR repeat-like domain DUF2894 PF11445.3 CDI76702.1 - 3.4 7.8 18.9 4.5 7.4 13.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2894) Glyco_hydro_2 PF00703.16 CDI76702.1 - 3.5 8.0 9.3 2.2 8.7 1.5 2.0 1 1 1 2 2 2 0 Glycosyl hydrolases family 2 Neur_chan_memb PF02932.11 CDI76702.1 - 3.7 7.3 17.4 4.1 7.2 12.0 1.0 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Herpes_UL87 PF03043.9 CDI76702.1 - 4.9 5.4 13.6 5.7 5.2 9.4 1.1 1 0 0 1 1 1 0 Herpesvirus UL87 family tRNA_synt_1c_R2 PF04557.10 CDI76702.1 - 5.7 7.7 11.4 4 8.2 2.4 2.1 2 0 0 2 2 2 0 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 NUC194 PF08163.7 CDI76702.1 - 5.9 5.6 16.8 7.4 5.3 11.7 1.2 1 0 0 1 1 1 0 NUC194 domain DUF3959 PF13105.1 CDI76702.1 - 6.2 6.0 10.2 8 5.7 7.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3959) FAM60A PF15396.1 CDI76702.1 - 6.5 6.4 17.9 7.8 6.1 12.4 1.1 1 0 0 1 1 1 0 Protein Family FAM60A Zip PF02535.17 CDI76702.1 - 6.6 5.6 7.8 8.7 5.2 5.4 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Cas_Csy2 PF09614.5 CDI76702.1 - 7.4 5.6 17.2 13 4.9 11.9 1.3 1 1 0 1 1 1 0 CRISPR-associated protein (Cas_Csy2) Herpes_DNAp_acc PF04929.7 CDI76702.1 - 7.7 5.3 15.0 8.9 5.1 10.4 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor DUF4407 PF14362.1 CDI76702.1 - 8.3 5.2 22.1 9.6 5.0 15.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) FlaG PF03646.10 CDI76702.1 - 9.5 6.4 25.2 5.4 7.1 7.4 2.2 2 0 0 2 2 2 0 FlaG protein DUF1510 PF07423.6 CDI76703.1 - 0.55 9.5 23.9 0.56 9.5 16.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) APG6 PF04111.7 CDI76703.1 - 1.6 7.7 28.7 1.6 7.7 19.9 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 Caldesmon PF02029.10 CDI76703.1 - 2.7 6.2 22.1 2.9 6.2 15.3 1.0 1 0 0 1 1 1 0 Caldesmon Gastrin PF00918.12 CDI76703.1 - 3.4 8.5 27.7 3.6 8.4 19.2 1.0 1 0 0 1 1 1 0 Gastrin/cholecystokinin family IncA PF04156.9 CDI76703.1 - 4.7 6.7 32.5 5.9 6.4 22.6 1.2 1 0 0 1 1 1 0 IncA protein NARP1 PF12569.3 CDI76703.1 - 5.1 5.7 26.3 5.4 5.6 18.2 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Ycf1 PF05758.7 CDI76703.1 - 7.2 4.1 23.3 6.7 4.2 16.1 1.0 1 0 0 1 1 1 0 Ycf1 FAM60A PF15396.1 CDI76706.1 - 6.8 6.3 25.2 8.4 6.0 17.5 1.2 1 0 0 1 1 1 0 Protein Family FAM60A DEPP PF15343.1 CDI76709.1 - 1.1 8.9 25.0 1.3 8.5 17.3 1.0 1 0 0 1 1 1 0 Decidual protein induced by progesterone family DUF4647 PF15504.1 CDI76709.1 - 7.6 5.2 19.4 9.1 5.0 13.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4647) Vfa1 PF08432.5 CDI76711.1 - 0.11 12.5 21.0 0.074 13.0 7.2 2.1 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 DUF4407 PF14362.1 CDI76711.1 - 0.13 11.1 10.5 0.2 10.5 7.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Gag_spuma PF03276.9 CDI76711.1 - 0.93 7.7 25.5 1.3 7.3 17.7 1.1 1 0 0 1 1 1 0 Spumavirus gag protein DUF1510 PF07423.6 CDI76711.1 - 2.1 7.6 27.3 0.018 14.4 7.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) DUF2897 PF11446.3 CDI76711.1 - 2.3 8.1 7.9 3.1 7.7 4.5 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF2897) Baculo_PP31 PF05311.6 CDI76711.1 - 2.3 7.3 17.8 1.8 7.7 4.9 2.2 2 0 0 2 2 2 0 Baculovirus 33KDa late protein (PP31) AIF_C PF14721.1 CDI76711.1 - 6.6 6.9 18.7 5.4 7.2 6.0 2.2 2 0 0 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term RRM_1 PF00076.17 CDI76750.1 - 8.6e-24 82.9 0.1 8.5e-16 57.3 0.0 3.3 2 1 1 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CDI76750.1 - 1.5e-18 66.5 0.0 4.2e-13 49.0 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CDI76750.1 - 2e-06 27.5 0.0 5.6e-05 22.9 0.0 2.6 2 1 1 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Cwf_Cwc_15 PF04889.7 CDI76750.1 - 0.83 9.3 39.8 0.07 12.8 1.1 3.2 3 0 0 3 3 3 0 Cwf15/Cwc15 cell cycle control protein RAP1 PF07218.6 CDI76750.1 - 4.1 5.3 11.9 6.1 4.7 8.3 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) TerD PF02342.13 CDI76751.1 - 9.5e-17 60.9 0.0 3.3e-16 59.1 0.0 1.8 2 0 0 2 2 2 1 TerD domain DUF2730 PF10805.3 CDI76751.1 - 0.0002 21.0 0.4 0.00041 20.0 0.3 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2730) Nsp1_C PF05064.8 CDI76751.1 - 0.04 13.5 0.2 0.084 12.5 0.1 1.5 1 0 0 1 1 1 0 Nsp1-like C-terminal region DUF4600 PF15372.1 CDI76751.1 - 0.094 12.9 2.2 1.6 8.9 1.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4600) Helicase_C PF00271.26 CDI76752.1 - 1.7e-25 88.7 0.0 5.5e-25 87.0 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF1253 PF06862.7 CDI76752.1 - 0.062 11.6 0.0 0.088 11.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1253) Dispanin PF04505.7 CDI76752.1 - 0.21 11.1 0.1 0.21 11.1 0.1 1.8 2 0 0 2 2 2 0 Interferon-induced transmembrane protein DEAD PF00270.24 CDI76754.1 - 3.5e-28 98.1 0.0 4.6e-28 97.8 0.0 1.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase Proteasome PF00227.21 CDI76755.1 - 2.3e-32 111.8 0.0 1.2e-17 63.8 0.0 2.2 1 1 1 2 2 2 2 Proteasome subunit Proteasome_A_N PF10584.4 CDI76755.1 - 1.3e-10 40.3 0.0 1.3e-10 40.3 0.0 2.1 3 0 0 3 3 3 1 Proteasome subunit A N-terminal signature ATPgrasp_YheCD PF14398.1 CDI76755.1 - 0.063 12.0 0.0 0.12 11.1 0.0 1.4 1 1 0 1 1 1 0 YheC/D like ATP-grasp RecA PF00154.16 CDI76755.1 - 0.12 11.3 0.0 0.17 10.9 0.0 1.2 1 0 0 1 1 1 0 recA bacterial DNA recombination protein IncA PF04156.9 CDI76764.1 - 0.00012 21.7 14.8 0.00015 21.4 10.2 1.1 1 0 0 1 1 1 1 IncA protein BTV_NS2 PF04514.7 CDI76764.1 - 0.0008 18.3 4.4 0.0008 18.3 3.0 1.2 1 0 0 1 1 1 1 Bluetongue virus non-structural protein NS2 VAD1-2 PF15310.1 CDI76764.1 - 0.011 15.4 16.3 0.015 15.0 11.3 1.2 1 0 0 1 1 1 0 Vitamin A-deficiency (VAD) rat model signalling eIF-3_zeta PF05091.7 CDI76764.1 - 0.016 13.8 12.6 0.016 13.8 8.8 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Suf PF05843.9 CDI76764.1 - 0.022 14.5 17.6 0.025 14.3 12.2 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Activator_LAG-3 PF11498.3 CDI76764.1 - 0.051 12.3 37.3 0.057 12.1 25.9 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Med15 PF09606.5 CDI76764.1 - 0.052 11.7 47.8 0.059 11.5 33.1 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal MRP-S31 PF15433.1 CDI76764.1 - 0.063 12.6 24.8 0.08 12.3 17.2 1.0 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 Raftlin PF15250.1 CDI76764.1 - 0.069 11.6 9.8 0.073 11.5 6.8 1.1 1 0 0 1 1 1 0 Raftlin FLO_LFY PF01698.11 CDI76764.1 - 0.084 11.7 14.7 0.11 11.3 10.2 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein AMP-binding PF00501.23 CDI76764.1 - 0.19 10.0 3.7 0.21 9.9 2.5 1.1 1 0 0 1 1 1 0 AMP-binding enzyme zf-DHHC PF01529.15 CDI76764.1 - 0.24 10.8 3.2 0.29 10.5 2.2 1.3 1 0 0 1 1 1 0 DHHC palmitoyltransferase PAT1 PF09770.4 CDI76764.1 - 0.24 9.6 35.7 0.26 9.4 24.7 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Baculo_PP31 PF05311.6 CDI76764.1 - 0.25 10.5 11.7 0.3 10.3 8.1 1.4 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) RNA_pol_Rpb1_5 PF04998.12 CDI76764.1 - 0.26 10.5 7.2 0.33 10.1 5.0 1.1 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 Pap_E4 PF02711.9 CDI76764.1 - 0.31 11.8 14.4 0.59 10.9 10.0 1.4 1 0 0 1 1 1 0 E4 protein UPF0560 PF10577.4 CDI76764.1 - 0.32 9.1 16.3 0.32 9.2 11.3 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Serinc PF03348.10 CDI76764.1 - 0.36 9.4 9.4 0.37 9.4 6.5 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) Zip PF02535.17 CDI76764.1 - 0.37 9.7 3.4 0.4 9.6 2.4 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter GAGA_bind PF06217.7 CDI76764.1 - 0.43 10.5 17.3 0.51 10.2 12.0 1.0 1 0 0 1 1 1 0 GAGA binding protein-like family FimP PF09766.4 CDI76764.1 - 0.47 9.4 24.0 0.6 9.1 16.6 1.1 1 0 0 1 1 1 0 Fms-interacting protein Glyco_transf_15 PF01793.11 CDI76764.1 - 0.48 9.3 11.6 0.63 8.9 8.0 1.2 1 0 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase Neur_chan_memb PF02932.11 CDI76764.1 - 0.5 10.2 7.9 0.53 10.1 5.5 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Ycf1 PF05758.7 CDI76764.1 - 0.61 7.7 12.5 0.68 7.5 8.6 1.0 1 0 0 1 1 1 0 Ycf1 Folate_carrier PF01770.13 CDI76764.1 - 0.67 8.4 5.0 0.72 8.2 3.4 1.2 1 0 0 1 1 1 0 Reduced folate carrier SAGA-Tad1 PF12767.2 CDI76764.1 - 0.68 9.5 18.6 0.84 9.2 12.9 1.1 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit SpoVR PF04293.8 CDI76764.1 - 0.71 8.1 9.7 0.74 8.1 6.8 1.1 1 0 0 1 1 1 0 SpoVR like protein SpoIIP PF07454.6 CDI76764.1 - 0.81 8.7 12.1 1.2 8.2 8.4 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) DUF342 PF03961.8 CDI76764.1 - 0.88 7.9 8.6 0.9 7.8 6.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) HemX PF04375.9 CDI76764.1 - 1.1 7.8 36.9 1.3 7.5 25.6 1.0 1 0 0 1 1 1 0 HemX Endonuc_Holl PF10107.4 CDI76764.1 - 1.3 8.6 12.7 2.1 8.0 8.8 1.3 1 0 0 1 1 1 0 Endonuclease related to archaeal Holliday junction resolvase Hom_end_hint PF05203.11 CDI76764.1 - 1.3 8.6 9.0 2 8.0 6.2 1.3 1 0 0 1 1 1 0 Hom_end-associated Hint Band_3_cyto PF07565.8 CDI76764.1 - 1.4 8.4 16.7 1.8 8.0 11.6 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain PMSI1 PF15322.1 CDI76764.1 - 1.4 7.8 13.7 1.9 7.5 9.5 1.2 1 0 0 1 1 1 0 Protein missing in infertile sperm 1, putative CRF1 PF10380.4 CDI76764.1 - 1.5 9.2 7.8 2.3 8.5 5.4 1.4 1 0 0 1 1 1 0 Transcription factor CRF1 FAM176 PF14851.1 CDI76764.1 - 1.6 8.3 8.1 2.8 7.6 5.6 1.4 1 0 0 1 1 1 0 FAM176 family Hex_IIIa PF02455.11 CDI76764.1 - 1.7 7.2 14.9 2 7.0 10.3 1.0 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) DUF2215 PF10225.4 CDI76764.1 - 1.7 7.9 8.3 2.1 7.7 5.7 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) PBP1_TM PF14812.1 CDI76764.1 - 1.8 8.8 9.8 3.1 8.1 6.8 1.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal PPP4R2 PF09184.6 CDI76764.1 - 1.9 7.9 12.8 2.6 7.5 8.9 1.1 1 0 0 1 1 1 0 PPP4R2 Gti1_Pac2 PF09729.4 CDI76764.1 - 2 8.2 10.4 3 7.6 7.2 1.4 1 0 0 1 1 1 0 Gti1/Pac2 family TFIIA PF03153.8 CDI76764.1 - 2.5 7.8 35.2 3.2 7.5 24.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Herpes_DNAp_acc PF04929.7 CDI76764.1 - 2.7 6.8 15.1 3.1 6.6 10.5 1.2 1 0 0 1 1 1 0 Herpes DNA replication accessory factor DUF4220 PF13968.1 CDI76764.1 - 3.4 6.6 6.1 3.9 6.4 4.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4220) Pex16 PF08610.5 CDI76764.1 - 3.9 6.3 14.3 5.4 5.9 9.9 1.2 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) DUF4638 PF15472.1 CDI76764.1 - 4.3 6.8 16.3 5.8 6.4 11.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) vMSA PF00695.14 CDI76764.1 - 4.7 6.2 10.0 5.2 6.1 7.0 1.1 1 0 0 1 1 1 0 Major surface antigen from hepadnavirus Mem_trans PF03547.13 CDI76764.1 - 5.1 5.2 5.7 5.7 5.1 3.9 1.1 1 0 0 1 1 1 0 Membrane transport protein NPR3 PF03666.8 CDI76764.1 - 5.4 5.4 15.2 7 5.0 10.6 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Sec62 PF03839.11 CDI76764.1 - 5.5 6.3 13.7 7.2 5.9 9.5 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 Bud13 PF09736.4 CDI76764.1 - 5.5 7.2 21.6 9.1 6.5 14.9 1.3 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex Paramyxo_ncap PF00973.14 CDI76764.1 - 5.6 5.5 13.1 6.7 5.2 9.1 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein YABBY PF04690.8 CDI76764.1 - 5.9 7.1 11.8 8.9 6.5 8.2 1.3 1 0 0 1 1 1 0 YABBY protein Peptidase_S15 PF02129.13 CDI76764.1 - 6.3 6.1 15.4 8.5 5.7 10.7 1.2 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Cellulose_synt PF03552.9 CDI76764.1 - 6.4 4.9 6.3 7.4 4.7 4.4 1.1 1 0 0 1 1 1 0 Cellulose synthase XRCC4 PF06632.7 CDI76764.1 - 6.5 5.4 17.1 8.3 5.1 11.8 1.1 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 DUF4512 PF14975.1 CDI76764.1 - 7.9 7.3 11.5 19 6.1 6.8 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4512) PBP_sp32 PF07222.7 CDI76764.1 - 9.8 5.2 18.9 11 5.0 13.1 1.1 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Abhydrolase_9_N PF15420.1 CDI76765.1 - 0.00027 20.7 4.1 0.00027 20.7 2.9 2.2 2 1 0 2 2 2 1 Alpha/beta-hydrolase family N-terminus DUF1183 PF06682.7 CDI76765.1 - 0.47 9.9 4.1 0.8 9.2 2.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) ODV-E18 PF10717.4 CDI76783.1 - 0.0022 17.4 0.5 0.014 14.8 0.0 2.7 2 1 1 3 3 3 1 Occlusion-derived virus envelope protein ODV-E18 FLO_LFY PF01698.11 CDI76783.1 - 0.23 10.2 63.8 0.18 10.5 20.9 2.2 2 0 0 2 2 2 0 Floricaula / Leafy protein ATP-synt_8 PF00895.15 CDI76783.1 - 0.24 11.6 0.3 0.24 11.6 0.2 2.9 3 1 0 3 3 3 0 ATP synthase protein 8 N6_N4_Mtase PF01555.13 CDI76783.1 - 3.7 6.9 19.2 1.5e+04 -6.1 13.3 3.3 1 1 0 1 1 1 0 DNA methylase DUF755 PF05501.6 CDI76786.1 - 0.015 15.3 20.1 0.015 15.3 14.0 4.1 3 1 1 4 4 4 0 Domain of unknown function (DUF755) DUF572 PF04502.8 CDI76786.1 - 1.1 8.4 28.9 1.6 7.8 20.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) Secretin_N_2 PF07655.8 CDI76786.1 - 2.6 8.5 40.4 1.9 8.9 12.1 2.9 3 0 0 3 3 3 0 Secretin N-terminal domain Utp14 PF04615.8 CDI76786.1 - 6.2 4.8 23.3 9.5 4.2 16.1 1.2 1 0 0 1 1 1 0 Utp14 protein Ank_2 PF12796.2 CDI76793.1 - 1.8e-24 85.8 0.0 7e-13 48.7 0.0 2.4 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.1 CDI76793.1 - 2.2e-17 62.6 0.3 5.9e-08 32.7 0.0 3.4 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 CDI76793.1 - 3e-15 56.2 0.2 1.4e-10 41.4 0.1 3.3 3 1 0 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.25 CDI76793.1 - 1e-13 50.3 0.3 2.2e-07 30.3 0.0 3.9 3 1 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.1 CDI76793.1 - 1e-11 43.8 0.0 7.8e-05 22.5 0.0 4.2 4 0 0 4 4 4 2 Ankyrin repeat LCD1 PF09798.4 CDI76802.1 - 0.094 10.6 4.2 0.12 10.3 2.9 1.0 1 0 0 1 1 1 0 DNA damage checkpoint protein HemX PF04375.9 CDI76812.1 - 0.0048 15.5 16.0 0.0048 15.5 11.1 1.6 1 1 1 2 2 2 1 HemX DUF4366 PF14283.1 CDI76812.1 - 0.0056 16.1 7.6 0.0072 15.7 5.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4366) Zip PF02535.17 CDI76812.1 - 0.013 14.5 7.9 0.014 14.4 5.5 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter CD20 PF04103.10 CDI76812.1 - 0.042 13.7 0.7 0.077 12.9 0.5 1.4 1 0 0 1 1 1 0 CD20-like family CAP_N PF01213.14 CDI76812.1 - 0.044 13.0 20.4 0.053 12.8 14.1 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Suf PF05843.9 CDI76812.1 - 0.37 10.4 17.3 0.54 9.9 12.0 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) VIT1 PF01988.14 CDI76812.1 - 0.56 9.6 4.5 0.14 11.6 0.5 1.7 2 0 0 2 2 2 0 VIT family Mito_fiss_reg PF05308.6 CDI76812.1 - 0.74 9.1 28.1 0.47 9.7 17.5 1.8 1 1 0 1 1 1 0 Mitochondrial fission regulator Shadoo PF14999.1 CDI76812.1 - 1.7 8.4 10.2 0.1 12.4 0.7 2.1 2 0 0 2 2 2 0 Shadow of prion protein, neuroprotective Neur_chan_memb PF02932.11 CDI76812.1 - 2.1 8.1 7.2 2.6 7.8 5.0 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Hid1 PF12722.2 CDI76812.1 - 2.3 5.7 6.0 2.5 5.6 4.2 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF3357 PF11837.3 CDI76812.1 - 5.1 6.9 10.1 4.5 7.1 5.2 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF3357) Rrp15p PF07890.7 CDI76812.1 - 6.2 6.8 14.8 0.72 9.9 6.1 1.9 2 0 0 2 2 2 0 Rrp15p DUF4407 PF14362.1 CDI76812.1 - 6.9 5.5 17.0 9.2 5.1 11.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) SelP_N PF04592.9 CDI76812.1 - 8.7 5.6 22.7 0.98 8.7 12.8 1.5 2 0 0 2 2 2 0 Selenoprotein P, N terminal region Abhydro_lipase PF04083.11 CDI76829.1 - 0.017 14.4 0.2 0.079 12.3 0.1 2.3 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region NPR3 PF03666.8 CDI76831.1 - 0.36 9.3 16.9 0.46 8.9 11.7 1.3 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 HCO3_cotransp PF00955.16 CDI76831.1 - 0.97 8.0 6.6 1.2 7.7 4.6 1.1 1 0 0 1 1 1 0 HCO3- transporter family Zip PF02535.17 CDI76831.1 - 1 8.3 7.3 1.2 8.0 5.1 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Ebola_NP PF05505.7 CDI76831.1 - 1.7 6.5 20.0 1.9 6.4 13.9 1.0 1 0 0 1 1 1 0 Ebola nucleoprotein DUF2828 PF11443.3 CDI76831.1 - 2.9 5.9 13.5 3.8 5.5 9.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) MDFI PF15316.1 CDI76831.1 - 4.1 7.3 15.3 5 7.0 10.6 1.1 1 0 0 1 1 1 0 MyoD family inhibitor PAT1 PF09770.4 CDI76831.1 - 4.4 5.4 58.1 4.8 5.3 40.3 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF3306 PF11748.3 CDI76831.1 - 5.5 7.6 27.1 0.57 10.8 7.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3306) Raftlin PF15250.1 CDI76831.1 - 8.8 4.7 20.6 12 4.2 14.3 1.3 1 0 0 1 1 1 0 Raftlin LMBR1 PF04791.11 CDI76841.1 - 0.00012 20.8 5.8 0.0048 15.5 0.0 2.6 1 1 1 2 2 2 1 LMBR1-like membrane protein Hid1 PF12722.2 CDI76867.1 - 0.02 12.5 28.0 0.024 12.3 19.4 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Med15 PF09606.5 CDI76867.1 - 0.026 12.7 32.4 0.032 12.4 22.5 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF4220 PF13968.1 CDI76867.1 - 0.085 11.9 7.1 0.098 11.7 4.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4220) DUF106 PF01956.11 CDI76867.1 - 0.17 11.4 5.7 0.05 13.1 1.0 1.9 1 1 1 2 2 2 0 Integral membrane protein DUF106 Utp14 PF04615.8 CDI76867.1 - 0.48 8.5 29.7 0.59 8.2 20.6 1.0 1 0 0 1 1 1 0 Utp14 protein SAGA-Tad1 PF12767.2 CDI76867.1 - 0.62 9.6 30.1 0.78 9.3 20.9 1.1 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit PAT1 PF09770.4 CDI76867.1 - 0.71 8.0 27.0 0.84 7.8 18.7 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 ORC6 PF05460.8 CDI76867.1 - 2.4 7.1 25.0 3 6.8 17.3 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Ribosomal_60s PF00428.14 CDI76867.1 - 2.7 8.4 11.5 5.2 7.5 8.0 1.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein CytochromB561_N PF09786.4 CDI76867.1 - 3.1 6.1 30.8 3.9 5.7 21.4 1.2 1 0 0 1 1 1 0 Cytochrome B561, N terminal Ebola_NP PF05505.7 CDI76867.1 - 3.2 5.6 16.4 3.8 5.4 11.3 1.1 1 0 0 1 1 1 0 Ebola nucleoprotein DUF936 PF06075.7 CDI76867.1 - 3.3 6.5 35.2 4.1 6.2 24.4 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) BTV_NS2 PF04514.7 CDI76867.1 - 8.8 5.0 14.9 12 4.6 10.3 1.3 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 IncA PF04156.9 CDI76879.1 - 0.0004 20.0 0.3 0.0004 20.0 0.2 5.1 4 1 1 5 5 5 1 IncA protein Med15 PF09606.5 CDI76884.1 - 0.00013 20.3 54.6 0.00014 20.2 37.8 1.1 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal PAT1 PF09770.4 CDI76884.1 - 0.0017 16.7 43.4 0.0022 16.3 30.1 1.1 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 FAM60A PF15396.1 CDI76884.1 - 0.0039 16.9 13.6 0.0039 16.9 9.4 2.1 2 0 0 2 2 2 1 Protein Family FAM60A Peptidase_S49_N PF08496.5 CDI76884.1 - 0.0065 16.2 10.5 0.0065 16.2 7.3 1.5 2 0 0 2 2 1 1 Peptidase family S49 N-terminal DUF605 PF04652.11 CDI76884.1 - 0.023 14.1 28.3 0.032 13.6 19.6 1.2 1 0 0 1 1 1 0 Vta1 like Apt1 PF10351.4 CDI76884.1 - 0.027 13.3 11.8 0.04 12.7 8.2 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain eIF-3_zeta PF05091.7 CDI76884.1 - 0.041 12.5 20.4 0.051 12.1 14.1 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Anoctamin PF04547.7 CDI76884.1 - 0.058 12.0 2.3 0.062 11.9 1.6 1.3 1 0 0 1 1 1 0 Calcium-activated chloride channel DUF2126 PF09899.4 CDI76884.1 - 0.087 10.8 13.3 0.12 10.4 9.2 1.1 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) Ycf1 PF05758.7 CDI76884.1 - 0.13 9.9 16.8 0.17 9.5 11.7 1.2 1 0 0 1 1 1 0 Ycf1 Hid1 PF12722.2 CDI76884.1 - 0.17 9.5 18.9 0.22 9.1 13.1 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein HemX PF04375.9 CDI76884.1 - 0.17 10.4 35.5 0.22 10.0 24.6 1.1 1 0 0 1 1 1 0 HemX SR-25 PF10500.4 CDI76884.1 - 0.27 10.6 38.2 0.35 10.3 10.4 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein AAA_11 PF13086.1 CDI76884.1 - 0.37 10.3 17.5 0.032 13.7 8.8 1.6 2 0 0 2 2 2 0 AAA domain Pox_Ag35 PF03286.9 CDI76884.1 - 0.41 10.1 16.3 0.036 13.5 7.4 1.8 2 0 0 2 2 2 0 Pox virus Ag35 surface protein Folate_carrier PF01770.13 CDI76884.1 - 0.46 8.9 8.1 0.71 8.3 5.6 1.5 1 0 0 1 1 1 0 Reduced folate carrier Ndc1_Nup PF09531.5 CDI76884.1 - 0.7 8.2 17.2 0.77 8.1 11.9 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup AUX_IAA PF02309.11 CDI76884.1 - 0.73 9.5 17.4 2.7 7.7 11.3 1.9 2 0 0 2 2 2 0 AUX/IAA family Herpes_UL87 PF03043.9 CDI76884.1 - 0.75 8.1 11.6 0.87 7.9 8.0 1.1 1 0 0 1 1 1 0 Herpesvirus UL87 family DUF4220 PF13968.1 CDI76884.1 - 0.89 8.5 9.0 1.5 7.8 6.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4220) CAF-1_p150 PF11600.3 CDI76884.1 - 1.4 8.2 34.5 1.3 8.3 14.8 2.0 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF3260 PF11658.3 CDI76884.1 - 2.2 6.3 16.1 2.8 5.9 11.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3260) Peptidase_U57 PF05582.7 CDI76884.1 - 2.3 7.0 13.4 3.6 6.4 9.3 1.3 1 0 0 1 1 1 0 YabG peptidase U57 DUF4448 PF14610.1 CDI76884.1 - 2.6 7.5 6.5 1.1e+02 2.2 4.5 2.5 1 1 0 1 1 1 0 Protein of unknown function (DUF4448) APG6 PF04111.7 CDI76884.1 - 2.6 7.0 22.9 4.2 6.3 15.9 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 Cellulose_synt PF03552.9 CDI76884.1 - 3.2 5.9 8.0 4.3 5.4 5.5 1.2 1 0 0 1 1 1 0 Cellulose synthase NARP1 PF12569.3 CDI76884.1 - 3.3 6.3 20.1 4.8 5.8 14.0 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 SAGA-Tad1 PF12767.2 CDI76884.1 - 3.3 7.3 26.6 0.18 11.4 14.0 1.9 2 0 0 2 2 2 0 Transcriptional regulator of RNA polII, SAGA, subunit DUF4045 PF13254.1 CDI76884.1 - 3.4 6.8 23.1 0.096 11.9 10.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4045) FemAB PF02388.11 CDI76884.1 - 3.4 6.2 18.8 4.7 5.7 13.1 1.1 1 0 0 1 1 1 0 FemAB family DUF4011 PF13195.1 CDI76884.1 - 4 7.4 11.3 7.8 6.4 7.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4011) AvrE PF11725.3 CDI76884.1 - 4.1 4.2 25.7 4.6 4.1 17.8 1.0 1 0 0 1 1 1 0 Pathogenicity factor DUF4446 PF14584.1 CDI76884.1 - 5.5 6.7 11.3 9.7 6.0 7.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) DUF822 PF05687.8 CDI76884.1 - 5.7 7.2 22.3 1.3 9.3 9.1 2.2 2 0 0 2 2 2 0 Plant protein of unknown function (DUF822) HCO3_cotransp PF00955.16 CDI76884.1 - 6.1 5.3 7.1 7.9 5.0 4.9 1.2 1 0 0 1 1 1 0 HCO3- transporter family CDC45 PF02724.9 CDI76884.1 - 7.1 4.5 22.1 0.052 11.5 9.4 1.6 2 0 0 2 2 2 0 CDC45-like protein DUF1510 PF07423.6 CDI76884.1 - 9.6 5.5 25.2 0.37 10.1 13.2 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) FliP PF00813.15 CDI76884.1 - 9.7 5.8 11.2 14 5.3 7.7 1.2 1 0 0 1 1 1 0 FliP family Asp-B-Hydro_N PF05279.6 CDI76884.1 - 9.9 5.9 15.9 15 5.3 11.0 1.3 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region E1-E2_ATPase PF00122.15 CDI76916.1 - 8.3e-15 54.4 1.9 8.3e-07 28.2 0.0 3.3 3 0 0 3 3 3 2 E1-E2 ATPase Hydrolase PF00702.21 CDI76916.1 - 2.4e-11 44.4 8.8 2.1e-06 28.3 2.7 4.3 4 1 0 4 4 4 3 haloacid dehalogenase-like hydrolase HAD PF12710.2 CDI76916.1 - 9.5e-10 38.9 0.0 0.00093 19.4 0.0 3.4 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 CDI76916.1 - 7.4e-06 25.8 0.1 5.6e-05 23.0 0.0 2.5 1 1 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 CDI76916.1 - 0.026 14.1 0.1 1.1 8.7 0.0 2.4 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase MFS_1 PF07690.11 CDI76921.1 - 6.4e-20 71.1 34.5 9.5e-20 70.5 20.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 CDI76921.1 - 4.9e-08 31.9 15.4 1.3e-05 24.0 6.4 2.8 1 1 2 3 3 3 2 Sugar (and other) transporter ATG22 PF11700.3 CDI76921.1 - 0.002 16.7 15.9 0.0023 16.4 4.0 2.2 2 0 0 2 2 2 2 Vacuole effluxer Atg22 like Nuc_H_symport PF03825.11 CDI76921.1 - 0.0057 15.4 0.7 0.0096 14.7 0.5 1.3 1 0 0 1 1 1 1 Nucleoside H+ symporter COX6C PF02937.10 CDI76921.1 - 0.13 12.1 0.0 0.87 9.5 0.1 2.2 2 0 0 2 2 2 0 Cytochrome c oxidase subunit VIc Methyltransf_8 PF05148.10 CDI76924.1 - 5.9e-46 156.8 0.0 1e-45 156.0 0.0 1.3 1 0 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_11 PF08241.7 CDI76924.1 - 7.9e-08 32.6 0.0 2.2e-07 31.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CDI76924.1 - 0.042 13.4 0.0 0.78 9.3 0.0 2.3 1 1 1 2 2 2 0 Methyltransferase domain Methyltransf_12 PF08242.7 CDI76924.1 - 0.099 13.1 0.0 3.4 8.2 0.0 2.8 1 1 1 2 2 2 0 Methyltransferase domain Macoilin PF09726.4 CDI76924.1 - 0.37 9.0 12.2 0.48 8.6 8.4 1.0 1 0 0 1 1 1 0 Transmembrane protein Sas10 PF09368.5 CDI76927.1 - 4.5e-21 74.7 5.8 4.5e-21 74.7 4.0 2.4 2 0 0 2 2 2 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.10 CDI76927.1 - 7.1e-20 70.9 2.9 4.6e-19 68.3 1.8 2.7 2 0 0 2 2 2 1 Sas10/Utp3/C1D family RRM_1 PF00076.17 CDI76931.1 - 9.6e-17 60.3 0.0 1.2e-16 60.1 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CDI76931.1 - 2.8e-14 52.8 0.0 3.5e-14 52.5 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CDI76931.1 - 3.5e-08 33.1 0.0 4.9e-08 32.6 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Rhomboid PF01694.17 CDI76932.1 - 5.2e-30 104.4 10.6 5.2e-30 104.4 7.3 2.0 2 0 0 2 2 2 1 Rhomboid family PseudoU_synth_2 PF00849.17 CDI76932.1 - 4.9e-08 32.9 0.0 9.8e-08 31.9 0.0 1.5 1 0 0 1 1 1 1 RNA pseudouridylate synthase DUF1751 PF08551.5 CDI76932.1 - 0.00014 22.0 0.8 0.00065 19.9 0.5 2.1 1 0 0 1 1 1 1 Eukaryotic integral membrane protein (DUF1751) DER1 PF04511.10 CDI76932.1 - 0.066 12.7 0.9 0.1 12.1 0.2 1.6 2 0 0 2 2 2 0 Der1-like family C2 PF00168.25 CDI76934.1 - 8.7e-08 31.9 0.2 7.6e-06 25.6 0.1 2.7 1 1 0 1 1 1 1 C2 domain Totivirus_coat PF05518.6 CDI76935.1 - 0.014 13.2 1.4 0.022 12.6 1.0 1.2 1 0 0 1 1 1 0 Totivirus coat protein DUF1126 PF06565.7 CDI76936.1 - 2.1e-23 81.4 1.4 1.9e-09 36.8 0.1 3.8 3 0 0 3 3 3 3 Repeat of unknown function (DUF1126) TBP PF00352.16 CDI76937.1 - 4.6e-11 41.9 0.0 2.9e-05 23.3 0.0 2.4 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) RNA_pol_Rpb2_6 PF00562.23 CDI76939.1 - 2.7e-85 286.4 0.0 3.2e-85 286.2 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_7 PF04560.15 CDI76939.1 - 8.7e-31 106.0 0.1 1.4e-30 105.3 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 SH2 PF00017.19 CDI76939.1 - 0.015 15.0 0.0 0.065 13.0 0.0 2.0 2 0 0 2 2 2 0 SH2 domain Med15 PF09606.5 CDI76945.1 - 0.022 12.9 52.1 0.031 12.5 36.1 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF1570 PF07607.6 CDI76945.1 - 0.13 12.2 4.5 1.1 9.3 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1570) PRP1_N PF06424.7 CDI76945.1 - 0.32 11.3 0.1 0.32 11.3 0.0 2.2 2 0 0 2 2 2 0 PRP1 splicing factor, N-terminal ChaC PF04752.7 CDI76945.1 - 0.9 9.4 3.8 1.9 8.4 2.6 1.4 1 0 0 1 1 1 0 ChaC-like protein Mnd1 PF03962.10 CDI76945.1 - 2.1 8.0 21.3 0.19 11.4 3.8 2.2 2 0 0 2 2 2 0 Mnd1 family Pex14_N PF04695.8 CDI76945.1 - 3.1 7.8 18.0 0.32 11.0 5.0 2.3 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region GET2 PF08690.5 CDI76946.1 - 0.35 10.0 5.8 0.43 9.7 4.1 1.1 1 0 0 1 1 1 0 GET complex subunit GET2 TFIIA PF03153.8 CDI76946.1 - 0.46 10.3 14.7 0.6 9.9 10.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Suf PF05843.9 CDI76946.1 - 4.6 6.8 7.9 5.9 6.5 5.5 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) PAT1 PF09770.4 CDI76946.1 - 5.8 5.0 21.9 6.6 4.8 15.1 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Ribosomal_60s PF00428.14 CDI76947.1 - 0.0012 19.2 16.1 0.023 15.0 5.5 2.4 2 0 0 2 2 2 2 60s Acidic ribosomal protein DUF2880 PF11082.3 CDI76948.1 - 0.42 10.5 3.1 0.69 9.8 2.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2880) Ribosomal_60s PF00428.14 CDI76948.1 - 0.98 9.8 8.8 0.31 11.4 4.1 1.7 2 0 0 2 2 2 0 60s Acidic ribosomal protein SR-25 PF10500.4 CDI76950.1 - 0.0054 16.2 1.8 0.0062 16.0 1.3 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Cwf_Cwc_15 PF04889.7 CDI76950.1 - 0.011 15.4 1.7 0.013 15.2 1.2 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein PspA_IM30 PF04012.7 CDI76950.1 - 0.013 14.8 6.3 0.013 14.8 4.4 1.6 2 0 0 2 2 2 0 PspA/IM30 family DUF1168 PF06658.7 CDI76950.1 - 0.016 14.7 5.6 0.016 14.7 3.9 2.2 2 1 1 3 3 3 0 Protein of unknown function (DUF1168) DASH_Spc19 PF08287.6 CDI76950.1 - 0.023 14.2 0.7 0.038 13.5 0.5 1.3 1 0 0 1 1 1 0 Spc19 Glypican PF01153.14 CDI76950.1 - 0.075 11.6 3.4 0.081 11.5 2.3 1.0 1 0 0 1 1 1 0 Glypican DUF3987 PF13148.1 CDI76950.1 - 0.12 10.9 5.2 0.14 10.6 3.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) Rtf2 PF04641.7 CDI76950.1 - 0.17 11.0 6.2 0.27 10.3 4.3 1.3 1 0 0 1 1 1 0 Rtf2 RING-finger DUF2951 PF11166.3 CDI76950.1 - 0.44 10.4 4.2 0.67 9.8 2.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2951) Dsh_C PF12316.3 CDI76950.1 - 0.51 10.4 8.0 0.46 10.5 4.9 1.3 2 0 0 2 2 1 0 Segment polarity protein dishevelled (Dsh) C terminal DUF1183 PF06682.7 CDI76950.1 - 2.4 7.7 8.0 2.8 7.4 5.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) DUF2763 PF10961.3 CDI76950.1 - 3.3 8.1 10.4 13 6.3 3.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2763) Gag_p17 PF00540.13 CDI76950.1 - 3.7 7.3 9.5 0.34 10.6 1.1 2.3 2 0 0 2 2 2 0 gag gene protein p17 (matrix protein) APC_CDC26 PF10471.4 CDI76950.1 - 8.1 7.2 7.6 2.6 8.8 2.3 2.1 1 1 1 2 2 2 0 Anaphase-promoting complex APC subunit 1 Nha1_C PF08619.5 CDI76952.1 - 1 8.5 24.5 1.1 8.4 17.0 1.0 1 0 0 1 1 1 0 Alkali metal cation/H+ antiporter Nha1 C terminus Spore_coat_CotO PF14153.1 CDI76952.1 - 1.1 8.7 40.9 1.3 8.4 28.3 1.0 1 0 0 1 1 1 0 Spore coat protein CotO DDRGK PF09756.4 CDI76952.1 - 1.2 8.4 38.3 1.7 8.0 26.5 1.2 1 0 0 1 1 1 0 DDRGK domain Raftlin PF15250.1 CDI76952.1 - 1.3 7.4 24.5 1.5 7.2 17.0 1.0 1 0 0 1 1 1 0 Raftlin PPP4R2 PF09184.6 CDI76952.1 - 1.3 8.4 29.0 1.5 8.2 20.1 1.0 1 0 0 1 1 1 0 PPP4R2 DUF1510 PF07423.6 CDI76952.1 - 1.5 8.1 33.0 1.8 7.8 22.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Nop53 PF07767.6 CDI76952.1 - 1.7 7.5 36.2 1.8 7.4 25.1 1.0 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) BTV_NS2 PF04514.7 CDI76952.1 - 2 7.2 25.1 2.3 7.0 17.4 1.0 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Fmp27_WPPW PF10359.4 CDI76952.1 - 2.2 6.6 29.3 2.5 6.4 20.3 1.0 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Rtf2 PF04641.7 CDI76952.1 - 3 6.9 24.0 3.4 6.7 16.6 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger FAM60A PF15396.1 CDI76952.1 - 3.1 7.4 22.1 3.8 7.2 15.3 1.0 1 0 0 1 1 1 0 Protein Family FAM60A F-protein PF00469.15 CDI76952.1 - 4.4 6.6 22.7 5.5 6.2 15.7 1.2 1 0 0 1 1 1 0 Negative factor, (F-Protein) or Nef DUF2894 PF11445.3 CDI76952.1 - 5.2 7.2 22.6 5.6 7.1 15.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2894) DUF4045 PF13254.1 CDI76952.1 - 7.5 5.7 23.3 8.6 5.5 16.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Daxx PF03344.10 CDI76952.1 - 9.3 4.5 30.9 14 3.9 21.4 1.2 1 0 0 1 1 1 0 Daxx Family Apt1 PF10351.4 CDI76952.1 - 10 4.8 20.1 11 4.7 13.9 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain SAGA-Tad1 PF12767.2 CDI76953.1 - 0.34 10.5 42.5 0.41 10.2 29.4 1.1 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit PAT1 PF09770.4 CDI76953.1 - 1.3 7.2 88.6 1.4 7.0 61.4 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Utp14 PF04615.8 CDI76953.1 - 1.8 6.6 43.6 2.1 6.4 30.2 1.0 1 0 0 1 1 1 0 Utp14 protein DUF4045 PF13254.1 CDI76953.1 - 2.2 7.4 32.8 2.7 7.1 22.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) DUF2217 PF10265.4 CDI76953.1 - 2.2 6.9 17.6 2.8 6.6 12.2 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) Daxx PF03344.10 CDI76953.1 - 2.9 6.2 39.3 3.2 6.1 27.3 1.0 1 0 0 1 1 1 0 Daxx Family PLRV_ORF5 PF01690.12 CDI76953.1 - 4.3 6.3 34.7 4.9 6.1 24.1 1.0 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein DUF1510 PF07423.6 CDI76954.1 - 1.1e-09 37.9 17.2 1.4e-09 37.6 11.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) DUF2514 PF10721.4 CDI76954.1 - 1.1e-06 28.3 5.6 1.5e-06 28.0 3.9 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2514) IncA PF04156.9 CDI76954.1 - 1.3e-06 28.2 20.8 1.5e-06 27.9 14.4 1.2 1 0 0 1 1 1 1 IncA protein Neur_chan_memb PF02932.11 CDI76954.1 - 1.4e-06 28.4 15.5 1.7e-06 28.1 10.7 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Tetraspannin PF00335.15 CDI76954.1 - 1.8e-06 27.4 8.3 2.7e-06 26.8 5.7 1.3 1 0 0 1 1 1 1 Tetraspanin family Peptidase_S49_N PF08496.5 CDI76954.1 - 2.2e-05 24.2 10.6 2.9e-05 23.9 7.3 1.1 1 0 0 1 1 1 1 Peptidase family S49 N-terminal DUF3260 PF11658.3 CDI76954.1 - 2.8e-05 22.4 13.0 3e-05 22.3 9.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3260) YfhO PF09586.5 CDI76954.1 - 0.00021 19.4 18.5 0.00024 19.3 12.8 1.0 1 0 0 1 1 1 1 Bacterial membrane protein YfhO Mem_trans PF03547.13 CDI76954.1 - 0.00026 19.4 18.4 0.00032 19.1 12.8 1.1 1 0 0 1 1 1 1 Membrane transport protein Ycf1 PF05758.7 CDI76954.1 - 0.0005 17.9 14.2 0.00057 17.7 9.9 1.0 1 0 0 1 1 1 1 Ycf1 DUF2217 PF10265.4 CDI76954.1 - 0.00078 18.3 16.8 0.00094 18.0 11.6 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2217) TMEM51 PF15345.1 CDI76954.1 - 0.0011 18.7 23.0 0.0017 18.0 15.9 1.4 1 0 0 1 1 1 1 Transmembrane protein 51 Shisa PF13908.1 CDI76954.1 - 0.0015 18.7 18.0 0.0015 18.7 12.5 2.0 1 1 1 2 2 1 1 Wnt and FGF inhibitory regulator DUF3365 PF11845.3 CDI76954.1 - 0.0016 18.3 6.2 0.0021 17.9 4.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3365) RIC3 PF15361.1 CDI76954.1 - 0.0019 18.4 15.5 0.0019 18.4 10.8 1.8 1 1 1 2 2 2 1 Resistance to inhibitors of cholinesterase homologue 3 SoxE PF06525.6 CDI76954.1 - 0.002 17.4 8.1 0.11 11.7 5.6 2.4 1 1 0 1 1 1 1 Sulfocyanin (SoxE) DcuC PF03606.10 CDI76954.1 - 0.0022 16.2 2.5 0.0022 16.2 1.7 2.0 1 1 1 2 2 1 1 C4-dicarboxylate anaerobic carrier SID-1_RNA_chan PF13965.1 CDI76954.1 - 0.0026 16.0 12.3 0.0032 15.7 8.5 1.2 1 0 0 1 1 1 1 dsRNA-gated channel SID-1 EcsB PF05975.7 CDI76954.1 - 0.0054 15.2 1.3 0.0062 15.0 0.9 1.2 1 0 0 1 1 1 1 Bacterial ABC transporter protein EcsB DUF2254 PF10011.4 CDI76954.1 - 0.0089 14.5 3.7 0.011 14.2 2.6 1.2 1 0 0 1 1 1 1 Predicted membrane protein (DUF2254) Ion_trans PF00520.26 CDI76954.1 - 0.014 14.6 0.0 0.018 14.2 0.0 1.2 1 0 0 1 1 1 0 Ion transport protein DUF318 PF03773.8 CDI76954.1 - 0.023 13.6 3.4 0.027 13.4 2.4 1.1 1 0 0 1 1 1 0 Predicted permease NicO PF03824.11 CDI76954.1 - 0.027 13.8 4.0 0.034 13.4 2.7 1.2 1 0 0 1 1 1 0 High-affinity nickel-transport protein FHIPEP PF00771.15 CDI76954.1 - 0.031 12.6 14.4 0.066 11.5 10.0 1.6 1 1 0 1 1 1 0 FHIPEP family Choline_transpo PF04515.7 CDI76954.1 - 0.031 13.0 1.8 0.043 12.5 1.2 1.5 1 1 0 1 1 1 0 Plasma-membrane choline transporter Endonuc_Holl PF10107.4 CDI76954.1 - 0.04 13.5 12.7 0.054 13.1 8.8 1.4 1 0 0 1 1 1 0 Endonuclease related to archaeal Holliday junction resolvase PRA1 PF03208.14 CDI76954.1 - 0.045 13.1 4.0 0.06 12.6 2.8 1.4 1 1 0 1 1 1 0 PRA1 family protein DUF805 PF05656.9 CDI76954.1 - 0.048 13.5 0.1 0.075 12.8 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF805) Hid1 PF12722.2 CDI76954.1 - 0.049 11.3 29.4 0.056 11.1 20.4 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF4220 PF13968.1 CDI76954.1 - 0.056 12.5 9.4 0.083 11.9 6.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4220) DUF4446 PF14584.1 CDI76954.1 - 0.061 13.1 15.0 0.1 12.4 10.3 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF4446) DUF2561 PF10812.3 CDI76954.1 - 0.062 12.8 5.4 0.17 11.4 3.8 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2561) Ni_hydr_CYTB PF01292.15 CDI76954.1 - 0.063 12.6 2.0 0.21 10.9 1.4 1.8 1 1 0 1 1 1 0 Prokaryotic cytochrome b561 RAP1 PF07218.6 CDI76954.1 - 0.066 11.3 20.2 0.083 10.9 14.0 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) TRAP_alpha PF03896.11 CDI76954.1 - 0.086 11.8 10.4 0.13 11.2 7.2 1.5 1 1 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Plasmodium_Vir PF05795.6 CDI76954.1 - 0.13 11.4 16.2 0.16 11.1 11.2 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein OAD_gamma PF04277.8 CDI76954.1 - 0.13 12.6 6.0 0.61 10.5 4.1 2.2 1 1 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain CD20 PF04103.10 CDI76954.1 - 0.13 12.1 15.9 21 5.0 11.0 2.4 1 1 0 1 1 1 0 CD20-like family Med15 PF09606.5 CDI76954.1 - 0.13 10.4 53.7 0.15 10.2 37.2 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Nucleoside_tran PF01733.13 CDI76954.1 - 0.14 11.2 14.1 0.36 9.9 9.7 1.6 1 1 0 1 1 1 0 Nucleoside transporter DUF3450 PF11932.3 CDI76954.1 - 0.15 11.2 28.5 0.19 10.9 19.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Nha1_C PF08619.5 CDI76954.1 - 0.18 11.0 27.7 0.22 10.7 19.2 1.0 1 0 0 1 1 1 0 Alkali metal cation/H+ antiporter Nha1 C terminus Frizzled PF01534.12 CDI76954.1 - 0.24 10.1 6.7 0.055 12.2 2.2 1.6 1 1 1 2 2 2 0 Frizzled/Smoothened family membrane region HemY_N PF07219.8 CDI76954.1 - 0.24 10.9 4.9 0.53 9.8 3.4 1.7 1 1 0 1 1 1 0 HemY protein N-terminus DUF4389 PF14333.1 CDI76954.1 - 0.24 11.1 7.5 0.38 10.4 5.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4389) DUF4131 PF13567.1 CDI76954.1 - 0.27 10.6 8.5 0.46 9.8 5.9 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4131) Menin PF05053.8 CDI76954.1 - 0.34 9.0 11.2 0.39 8.8 7.7 1.0 1 0 0 1 1 1 0 Menin SpoIIIAH PF12685.2 CDI76954.1 - 0.42 10.0 30.8 5 6.5 21.4 2.2 1 1 0 1 1 1 0 SpoIIIAH-like protein DDRGK PF09756.4 CDI76954.1 - 0.45 9.8 24.0 0.55 9.6 16.6 1.1 1 0 0 1 1 1 0 DDRGK domain FA_desaturase PF00487.19 CDI76954.1 - 0.6 9.5 6.2 0.98 8.8 4.3 1.5 1 1 0 1 1 1 0 Fatty acid desaturase NARP1 PF12569.3 CDI76954.1 - 0.66 8.6 15.3 0.78 8.4 10.6 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 SOG2 PF10428.4 CDI76954.1 - 0.69 8.5 29.0 0.88 8.1 20.1 1.0 1 0 0 1 1 1 0 RAM signalling pathway protein ASFV_J13L PF05568.6 CDI76954.1 - 0.85 9.1 8.1 2.1 7.8 5.6 1.7 1 1 0 1 1 1 0 African swine fever virus J13L protein ALG3 PF05208.8 CDI76954.1 - 0.86 8.7 6.7 1.1 8.4 4.6 1.3 1 0 0 1 1 1 0 ALG3 protein DUF4199 PF13858.1 CDI76954.1 - 0.87 9.4 15.7 6.2 6.7 10.9 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF4199) CKAP2_C PF15297.1 CDI76954.1 - 0.95 8.2 22.5 1.1 7.9 15.6 1.1 1 0 0 1 1 1 0 Cytoskeleton-associated protein 2 C-terminus Pex24p PF06398.6 CDI76954.1 - 1.1 8.0 11.0 2.6 6.7 7.5 1.8 1 1 0 1 1 1 0 Integral peroxisomal membrane peroxin TT_ORF1 PF02956.9 CDI76954.1 - 1.1 7.6 19.4 1.3 7.3 13.5 1.0 1 0 0 1 1 1 0 TT viral orf 1 LpxB PF02684.10 CDI76954.1 - 1.3 7.5 10.1 1.8 7.1 7.0 1.1 1 0 0 1 1 1 0 Lipid-A-disaccharide synthetase FAM176 PF14851.1 CDI76954.1 - 1.8 8.2 21.8 0.13 11.9 2.3 2.1 1 1 1 2 2 2 0 FAM176 family Ebola_NP PF05505.7 CDI76954.1 - 1.9 6.4 26.0 2.3 6.1 18.0 1.0 1 0 0 1 1 1 0 Ebola nucleoprotein DUF3573 PF12097.3 CDI76954.1 - 1.9 7.0 24.8 2.3 6.7 17.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) RskA PF10099.4 CDI76954.1 - 2 8.0 15.0 17 5.0 10.4 2.0 1 1 0 1 1 1 0 Anti-sigma-K factor rskA Bud13 PF09736.4 CDI76954.1 - 2.1 8.6 24.9 2.6 8.2 17.3 1.2 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex DUF2500 PF10694.4 CDI76954.1 - 2.1 8.3 17.4 9.3 6.3 12.1 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF2500) DUF3373 PF11853.3 CDI76954.1 - 2.2 6.7 16.2 2.7 6.3 11.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) Na_trans_assoc PF06512.8 CDI76954.1 - 2.3 8.1 20.3 3.8 7.4 14.1 1.3 1 0 0 1 1 1 0 Sodium ion transport-associated Rer1 PF03248.8 CDI76954.1 - 2.4 7.7 9.8 6.3 6.3 6.8 1.7 1 1 0 1 1 1 0 Rer1 family Folate_carrier PF01770.13 CDI76954.1 - 2.5 6.5 21.6 8.6 4.7 14.9 1.8 1 1 0 1 1 1 0 Reduced folate carrier eIF-3_zeta PF05091.7 CDI76954.1 - 2.5 6.5 26.1 3 6.3 18.1 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Neur PF00064.13 CDI76954.1 - 2.6 6.0 13.6 4.5 5.2 9.4 1.5 1 1 0 1 1 1 0 Neuraminidase PIG-S PF10510.4 CDI76954.1 - 2.8 6.4 27.5 3.4 6.2 19.0 1.0 1 0 0 1 1 1 0 Phosphatidylinositol-glycan biosynthesis class S protein DUF4045 PF13254.1 CDI76954.1 - 3.3 6.8 30.3 4 6.6 21.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) G0-G1_switch_2 PF15103.1 CDI76954.1 - 4.5 7.5 19.6 42 4.4 13.6 2.1 1 1 0 1 1 1 0 G0/G1 switch protein 2 Gastrin PF00918.12 CDI76954.1 - 4.6 8.0 29.5 0.69 10.7 16.9 2.0 1 1 1 2 2 2 0 Gastrin/cholecystokinin family Draxin PF15550.1 CDI76954.1 - 4.7 6.7 21.3 5.8 6.4 14.8 1.1 1 0 0 1 1 1 0 Draxin CDC73 PF05179.9 CDI76954.1 - 4.8 6.4 22.2 5.7 6.2 15.4 1.0 1 0 0 1 1 1 0 RNA pol II accessory factor, Cdc73 family DUF2852 PF11014.3 CDI76954.1 - 4.9 7.1 11.5 34 4.4 8.0 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF2852) FAM220 PF15487.1 CDI76954.1 - 5.6 6.2 27.7 7.1 5.9 19.2 1.0 1 0 0 1 1 1 0 FAM220 family Macoilin PF09726.4 CDI76954.1 - 6.8 4.8 38.4 8.7 4.4 26.6 1.1 1 0 0 1 1 1 0 Transmembrane protein Nop25 PF09805.4 CDI76954.1 - 8 6.5 27.6 9.9 6.2 19.1 1.1 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) TFIIF_alpha PF05793.7 CDI76954.1 - 8.3 4.6 28.3 10 4.3 19.6 1.0 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) ETRAMP PF09716.5 CDI76954.1 - 8.5 6.4 8.3 1e+02 2.9 5.8 2.7 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) Med15 PF09606.5 CDI76964.1 - 0.18 9.9 62.9 0.31 9.2 43.6 1.4 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Actin PF00022.14 CDI76967.1 - 5.8e-06 24.9 0.0 5.8e-06 24.9 0.0 2.8 3 0 0 3 3 3 1 Actin BAF1_ABF1 PF04684.8 CDI76967.1 - 0.0026 16.7 22.2 0.0026 16.7 15.4 7.4 4 2 2 7 7 7 2 BAF1 / ABF1 chromatin reorganising factor N6_N4_Mtase PF01555.13 CDI76967.1 - 0.037 13.5 3.2 13 5.2 2.2 3.6 1 1 0 1 1 1 0 DNA methylase RAP1 PF07218.6 CDI76967.1 - 5.4 4.9 17.2 0.07 11.2 2.6 2.3 2 0 0 2 2 2 0 Rhoptry-associated protein 1 (RAP-1) PTPS PF01242.14 CDI76972.1 - 3.5e-09 36.4 3.5 4.5e-05 23.1 0.1 2.7 2 1 1 3 3 2 2 6-pyruvoyl tetrahydropterin synthase Otopetrin PF03189.8 CDI76972.1 - 0.068 12.1 1.0 0.068 12.1 0.7 1.2 1 0 0 1 1 1 0 Otopetrin Band_3_cyto PF07565.8 CDI76972.1 - 0.096 12.1 5.3 0.11 11.9 3.7 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Spt20 PF12090.3 CDI76972.1 - 0.12 11.6 7.4 0.2 11.0 5.1 1.4 1 0 0 1 1 1 0 Spt20 family DUF4199 PF13858.1 CDI76972.1 - 0.13 12.1 1.5 1.3 8.9 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4199) CDK5_activator PF03261.10 CDI76972.1 - 0.14 11.4 14.2 0.26 10.6 9.9 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein Macoilin PF09726.4 CDI76972.1 - 0.51 8.5 21.3 0.65 8.2 14.8 1.1 1 0 0 1 1 1 0 Transmembrane protein PAT1 PF09770.4 CDI76972.1 - 0.6 8.2 29.0 0.93 7.6 20.1 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Hid1 PF12722.2 CDI76972.1 - 0.77 7.3 7.9 0.89 7.1 5.5 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein PBP1_TM PF14812.1 CDI76972.1 - 3.3 8.0 7.5 17 5.7 0.2 2.2 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF4557 PF15101.1 CDI76972.1 - 3.7 7.3 17.8 0.64 9.8 9.6 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4557) Neur_chan_memb PF02932.11 CDI76972.1 - 4.7 7.0 8.0 6.8 6.4 5.5 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF3245 PF11595.3 CDI76972.1 - 4.9 7.4 18.9 0.13 12.5 2.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3245) Peptidase_S64 PF08192.6 CDI76972.1 - 7.1 4.8 15.1 10 4.3 10.4 1.2 1 0 0 1 1 1 0 Peptidase family S64 RIC3 PF15361.1 CDI76972.1 - 9.9 6.3 15.0 74 3.5 9.8 2.1 2 0 0 2 2 2 0 Resistance to inhibitors of cholinesterase homologue 3 PBP PF01161.15 CDI76985.1 - 2.1e-20 73.0 0.1 5.1e-20 71.8 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein SAPS PF04499.10 CDI76985.1 - 0.0013 17.4 7.8 0.0018 16.9 5.4 1.1 1 0 0 1 1 1 1 SIT4 phosphatase-associated protein Spore_coat_CotO PF14153.1 CDI76985.1 - 0.005 16.3 17.7 0.005 16.3 12.3 2.1 2 0 0 2 2 2 1 Spore coat protein CotO SAGA-Tad1 PF12767.2 CDI76985.1 - 0.0064 16.1 10.2 0.0064 16.1 7.1 2.1 2 0 0 2 2 2 1 Transcriptional regulator of RNA polII, SAGA, subunit TFIIA PF03153.8 CDI76985.1 - 0.0093 15.9 40.8 0.022 14.6 20.3 2.1 2 0 0 2 2 2 2 Transcription factor IIA, alpha/beta subunit Herpes_env PF01673.13 CDI76985.1 - 0.24 9.9 9.6 0.1 11.1 3.9 1.9 2 0 0 2 2 2 0 Herpesvirus putative major envelope glycoprotein GAGA_bind PF06217.7 CDI76985.1 - 0.29 11.0 17.1 0.088 12.7 7.2 2.1 2 0 0 2 2 2 0 GAGA binding protein-like family TraV PF09676.5 CDI76985.1 - 0.49 11.1 15.3 0.019 15.6 3.9 2.3 2 0 0 2 2 2 0 Type IV conjugative transfer system lipoprotein (TraV) PAT1 PF09770.4 CDI76985.1 - 0.58 8.3 61.7 0.41 8.8 30.9 2.0 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 Apt1 PF10351.4 CDI76985.1 - 0.63 8.8 11.1 0.43 9.3 4.7 2.0 2 0 0 2 2 2 0 Golgi-body localisation protein domain Kei1 PF08552.6 CDI76985.1 - 0.86 9.2 13.1 1.3 8.5 6.1 2.1 2 0 0 2 2 2 0 Inositolphosphorylceramide synthase subunit Kei1 DUF4045 PF13254.1 CDI76985.1 - 1.5 8.0 19.2 1.2 8.2 10.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4045) FAM222A PF15258.1 CDI76985.1 - 1.6 7.8 33.4 0.27 10.4 15.2 2.1 2 0 0 2 2 2 0 Protein family of FAM222A Cellulose_synt PF03552.9 CDI76985.1 - 2 6.5 8.5 11 4.1 0.0 2.0 2 0 0 2 2 2 0 Cellulose synthase Dicty_REP PF05086.7 CDI76985.1 - 2.2 5.9 13.0 0.098 10.4 4.6 1.7 2 0 0 2 2 2 0 Dictyostelium (Slime Mold) REP protein Bul1_N PF04425.7 CDI76985.1 - 2.3 6.6 18.7 0.13 10.7 7.5 2.0 2 0 0 2 2 2 0 Bul1 N terminus AUX_IAA PF02309.11 CDI76985.1 - 2.8 7.6 16.8 7.5 6.2 8.8 2.2 2 0 0 2 2 2 0 AUX/IAA family Peptidase_U57 PF05582.7 CDI76985.1 - 3.2 6.6 11.7 0.18 10.7 2.5 2.1 2 0 0 2 2 2 0 YabG peptidase U57 AAA_11 PF13086.1 CDI76985.1 - 3.4 7.1 21.1 4.6 6.7 10.9 2.1 2 0 0 2 2 2 0 AAA domain Senescence_reg PF04520.8 CDI76985.1 - 4.1 7.8 14.8 5.6 7.4 7.2 2.1 2 0 0 2 2 2 0 Senescence regulator CPSF100_C PF13299.1 CDI76985.1 - 4.7 7.3 18.8 15 5.7 9.2 2.2 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal Mem_trans PF03547.13 CDI76985.1 - 4.8 5.3 9.0 4 5.6 2.4 2.1 2 0 0 2 2 2 0 Membrane transport protein Band_3_cyto PF07565.8 CDI76985.1 - 5.2 6.5 23.2 9.1 5.7 0.9 2.8 3 0 0 3 3 3 0 Band 3 cytoplasmic domain DUF1510 PF07423.6 CDI76985.1 - 5.4 6.3 28.2 4.5 6.5 14.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) FAM60A PF15396.1 CDI76985.1 - 8.8 6.0 18.4 27 4.4 10.1 2.1 2 0 0 2 2 2 0 Protein Family FAM60A HAUS5 PF14817.1 CDI76987.1 - 0.019 13.5 8.5 0.024 13.1 5.9 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 5 DUF3138 PF11336.3 CDI76987.1 - 0.045 11.9 18.3 0.052 11.7 12.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) UPF0565 PF10561.4 CDI76987.1 - 0.061 12.2 0.9 0.055 12.3 0.6 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0565 Activator_LAG-3 PF11498.3 CDI76987.1 - 0.086 11.5 10.9 0.11 11.2 7.6 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Med15 PF09606.5 CDI76987.1 - 0.13 10.4 16.7 0.16 10.1 11.6 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Herpes_capsid PF06112.6 CDI76987.1 - 0.18 11.8 6.4 0.26 11.3 4.4 1.2 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein CDK2AP PF09806.4 CDI76987.1 - 0.23 11.6 16.2 0.37 10.9 11.2 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein DUF4259 PF14078.1 CDI76987.1 - 0.3 11.5 11.7 0.15 12.5 0.4 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4259) FAD-oxidase_C PF02913.14 CDI76987.1 - 0.43 9.8 7.0 0.58 9.4 4.8 1.2 1 0 0 1 1 1 0 FAD linked oxidases, C-terminal domain DUF4657 PF15552.1 CDI76987.1 - 0.45 9.7 8.8 0.59 9.3 6.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4657) SpaB_C PF14028.1 CDI76987.1 - 0.6 9.6 14.8 0.76 9.2 10.3 1.2 1 0 0 1 1 1 0 SpaB C-terminal domain Phage_Gp23 PF10669.4 CDI76987.1 - 1.2 9.3 4.7 2.5 8.2 3.3 1.5 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) DUF2819 PF10995.3 CDI76987.1 - 1.3 7.7 8.3 1.9 7.1 5.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2819) FliD_N PF02465.13 CDI76987.1 - 2 8.8 15.7 3.5 8.0 10.9 1.3 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 N-terminus BAF1_ABF1 PF04684.8 CDI76987.1 - 5.7 5.6 22.6 8.2 5.1 15.5 1.3 1 1 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor DUF4316 PF14195.1 CDI76987.1 - 6.3 6.9 6.8 6.9 6.8 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4316) FNIP_N PF14636.1 CDI76988.1 - 0.1 13.0 5.2 0.12 12.8 3.0 1.4 2 0 0 2 2 2 0 Folliculin-interacting protein N-terminus Activator_LAG-3 PF11498.3 CDI76991.1 - 0.047 12.4 13.3 0.064 12.0 9.2 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 HEAT PF02985.17 CDI76992.1 - 0.0055 16.6 0.3 0.019 14.9 0.2 2.0 1 0 0 1 1 1 1 HEAT repeat Ribosomal_60s PF00428.14 CDI76992.1 - 0.021 15.1 1.0 0.021 15.1 0.7 3.2 4 0 0 4 4 4 0 60s Acidic ribosomal protein Packaging_FI PF14000.1 CDI76992.1 - 0.2 11.8 10.6 0.59 10.3 1.7 2.5 2 0 0 2 2 2 0 DNA packaging protein FI DUF2371 PF10177.4 CDI76992.1 - 0.34 10.7 1.9 0.81 9.5 1.4 1.7 1 1 0 1 1 1 0 Uncharacterised conserved protein (DUF2371) Zip PF02535.17 CDI76992.1 - 0.43 9.5 2.8 0.77 8.7 1.9 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter RNA_pol_Rpb1_5 PF04998.12 CDI76992.1 - 0.86 8.8 6.1 1.2 8.3 4.2 1.3 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 DHHW PF14286.1 CDI76992.1 - 1.5 8.0 9.9 2.3 7.4 6.9 1.3 1 0 0 1 1 1 0 DHHW protein DUF912 PF06024.7 CDI76992.1 - 1.5 8.8 15.8 2 8.4 0.9 3.0 3 0 0 3 3 3 0 Nucleopolyhedrovirus protein of unknown function (DUF912) PBP1_TM PF14812.1 CDI76992.1 - 1.6 9.1 13.1 1.4 9.2 1.7 2.6 3 0 0 3 3 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal FAM176 PF14851.1 CDI76992.1 - 2.7 7.6 13.0 3.2 7.4 1.5 3.0 3 0 0 3 3 3 0 FAM176 family DUF506 PF04720.7 CDI76992.1 - 3.5 7.2 12.0 4.4 6.8 2.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF506) ARL6IP6 PF15062.1 CDI76992.1 - 6.9 6.6 15.3 0.052 13.4 2.6 3.1 2 1 2 4 4 4 0 Haemopoietic lineage transmembrane helix RNA_pol_Rpc4 PF05132.9 CDI76992.1 - 7 6.6 19.2 0.66 9.9 1.9 2.6 3 0 0 3 3 3 0 RNA polymerase III RPC4 Rtf2 PF04641.7 CDI76992.1 - 7.4 5.6 18.6 0.24 10.5 8.0 1.9 2 0 0 2 2 2 0 Rtf2 RING-finger EIIBC-GUT_N PF03612.9 CDI76992.1 - 7.9 6.0 17.9 3.6 7.1 1.6 2.7 3 0 0 3 3 3 0 Sorbitol phosphotransferase enzyme II N-terminus Vfa1 PF08432.5 CDI77003.1 - 5.9 6.8 26.7 6.4 6.7 18.5 1.0 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Zip PF02535.17 CDI77004.1 - 0.029 13.3 0.4 0.041 12.8 0.3 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter DUF2370 PF10176.4 CDI77004.1 - 0.034 13.4 4.7 0.065 12.5 3.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) Consortin_C PF15281.1 CDI77004.1 - 0.31 10.5 6.0 0.21 11.1 2.8 1.6 1 1 1 2 2 2 0 Consortin C-terminus Activator_LAG-3 PF11498.3 CDI77004.1 - 0.36 9.5 69.4 0.53 8.9 48.1 1.3 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Peptidase_M56 PF05569.6 CDI77004.1 - 1.2 8.0 7.4 2 7.3 5.1 1.3 1 0 0 1 1 1 0 BlaR1 peptidase M56 TFIIA PF03153.8 CDI77004.1 - 1.7 8.4 31.4 0.14 11.9 18.5 1.6 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit MDFI PF15316.1 CDI77004.1 - 2.5 8.0 7.9 5.1 7.0 5.3 1.7 1 1 0 1 1 1 0 MyoD family inhibitor SPT6_acidic PF14632.1 CDI77005.1 - 1.1e-09 38.3 10.3 1.1e-09 38.3 7.1 12.3 11 3 2 13 13 13 1 Acidic N-terminal SPT6 SR-25 PF10500.4 CDI77005.1 - 0.00037 20.0 11.2 0.00037 20.0 7.8 15.1 10 4 5 15 15 15 3 Nuclear RNA-splicing-associated protein DUF1510 PF07423.6 CDI77006.1 - 0.22 10.8 38.6 0.26 10.6 26.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) NPR3 PF03666.8 CDI77006.1 - 0.82 8.1 31.9 0.92 7.9 22.1 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Pox_Ag35 PF03286.9 CDI77006.1 - 1.1 8.7 22.1 1.3 8.4 15.3 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein SAPS PF04499.10 CDI77006.1 - 1.2 7.7 33.6 1.4 7.4 23.3 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Rhabdo_ncap PF00945.13 CDI77006.1 - 2.3 6.7 14.7 2.8 6.4 10.2 1.1 1 0 0 1 1 1 0 Rhabdovirus nucleocapsid protein Caldesmon PF02029.10 CDI77006.1 - 3.3 6.0 33.4 4 5.7 23.1 1.0 1 0 0 1 1 1 0 Caldesmon DUF4045 PF13254.1 CDI77006.1 - 3.6 6.7 31.9 4.4 6.4 22.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Raftlin PF15250.1 CDI77006.1 - 4 5.8 33.0 4.7 5.6 22.8 1.0 1 0 0 1 1 1 0 Raftlin DUF2052 PF09747.4 CDI77006.1 - 4.5 7.1 41.4 5.9 6.7 28.7 1.2 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) FAM60A PF15396.1 CDI77006.1 - 5.8 6.5 32.6 7 6.3 22.6 1.0 1 0 0 1 1 1 0 Protein Family FAM60A Hid1 PF12722.2 CDI77006.1 - 8.2 3.9 39.9 8.7 3.8 27.7 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Rtf2 PF04641.7 CDI77006.1 - 8.7 5.4 36.6 12 5.0 25.4 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger SMC_N PF02463.14 CDI77007.1 - 2.8e-18 65.9 0.8 1.1e-17 63.9 0.0 1.9 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 CDI77007.1 - 1.5e-08 34.9 0.6 2e-08 34.5 0.0 1.4 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 CDI77007.1 - 1.9e-07 30.4 0.0 5.4e-07 29.0 0.0 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.1 CDI77007.1 - 4.6e-06 26.7 5.1 4.6e-06 26.7 3.5 1.6 2 0 0 2 2 2 1 AAA ATPase domain ABC_tran PF00005.22 CDI77007.1 - 0.00014 22.1 1.0 0.00055 20.2 0.6 2.0 1 1 0 1 1 1 1 ABC transporter Zeta_toxin PF06414.7 CDI77007.1 - 0.013 14.5 2.7 0.068 12.2 1.9 2.0 1 1 1 2 2 2 0 Zeta toxin AAA_23 PF13476.1 CDI77007.1 - 0.018 15.3 21.0 0.082 13.2 12.0 3.0 1 1 1 2 2 1 0 AAA domain AAA_22 PF13401.1 CDI77007.1 - 0.024 14.7 0.1 0.049 13.7 0.1 1.6 1 1 0 1 1 1 0 AAA domain BUD22 PF09073.5 CDI77007.1 - 0.03 13.4 14.7 0.04 13.0 10.2 1.2 1 0 0 1 1 1 0 BUD22 DUF258 PF03193.11 CDI77007.1 - 0.037 13.2 0.0 0.071 12.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 MobB PF03205.9 CDI77007.1 - 0.056 13.1 0.2 0.37 10.5 0.0 2.2 1 1 1 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_5 PF07728.9 CDI77007.1 - 0.084 12.5 0.1 0.48 10.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) MAT1 PF06391.8 CDI77007.1 - 3.7 7.0 12.3 1.1 8.8 5.1 2.0 2 0 0 2 2 2 0 CDK-activating kinase assembly factor MAT1 Ndc1_Nup PF09531.5 CDI77010.1 - 2.1 6.6 4.5 3.3 6.0 3.1 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup LMF1 PF06762.9 CDI77011.1 - 1.5e-13 50.3 0.0 2.7e-13 49.4 0.0 1.4 1 0 0 1 1 1 1 Lipase maturation factor DUF3753 PF12575.3 CDI77015.1 - 0.015 15.0 3.3 0.026 14.2 2.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3753) CDC45 PF02724.9 CDI77015.1 - 0.91 7.4 16.5 1.1 7.2 11.5 1.0 1 0 0 1 1 1 0 CDC45-like protein DDRGK PF09756.4 CDI77015.1 - 2.2 7.6 29.7 2.5 7.4 20.6 1.1 1 0 0 1 1 1 0 DDRGK domain DUF4400 PF14348.1 CDI77015.1 - 3.6 6.9 13.1 4.3 6.6 9.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4400) NDUF_B5 PF09781.4 CDI77015.1 - 4.5 6.5 8.8 0.45 9.7 2.6 1.7 1 1 1 2 2 2 0 NADH:ubiquinone oxidoreductase, NDUFB5/SGDH subunit DUF3492 PF11997.3 CDI77015.1 - 5.4 6.4 15.1 5.6 6.4 10.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3492) Fmp27_WPPW PF10359.4 CDI77015.1 - 7.1 4.9 25.5 7.9 4.7 17.7 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain RNA_pol_Rpb1_1 PF04997.7 CDI77015.1 - 8 5.6 18.0 9.5 5.3 12.5 1.0 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 1 Peptidase_U57 PF05582.7 CDI77015.1 - 9.2 5.1 16.5 12 4.7 11.5 1.3 1 0 0 1 1 1 0 YabG peptidase U57 SprA-related PF12118.3 CDI77019.1 - 0.042 13.1 18.9 0.038 13.3 13.1 1.1 1 0 0 1 1 1 0 SprA-related family YqfQ PF14181.1 CDI77019.1 - 0.082 12.9 11.1 0.088 12.8 7.7 1.2 1 0 0 1 1 1 0 YqfQ-like protein Tim54 PF11711.3 CDI77019.1 - 0.14 10.7 7.7 0.13 10.7 5.3 1.0 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 FimP PF09766.4 CDI77019.1 - 0.15 11.0 17.8 0.15 11.0 12.3 1.0 1 0 0 1 1 1 0 Fms-interacting protein FLO_LFY PF01698.11 CDI77019.1 - 0.18 10.6 6.9 0.16 10.7 4.8 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein AAA_23 PF13476.1 CDI77019.1 - 0.21 11.9 10.6 0.19 12.0 7.3 1.1 1 0 0 1 1 1 0 AAA domain RR_TM4-6 PF06459.7 CDI77019.1 - 0.22 11.3 11.8 0.2 11.5 8.2 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF3408 PF11888.3 CDI77019.1 - 0.22 11.4 9.7 0.22 11.4 6.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) zf-DHHC PF01529.15 CDI77019.1 - 0.37 10.1 4.7 0.32 10.3 3.3 1.1 1 0 0 1 1 1 0 DHHC palmitoyltransferase Band_3_cyto PF07565.8 CDI77019.1 - 0.48 9.9 6.7 0.42 10.0 4.6 1.0 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Med15 PF09606.5 CDI77019.1 - 0.86 7.7 24.5 0.75 7.9 16.9 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF775 PF05603.7 CDI77019.1 - 0.87 9.0 8.2 0.78 9.2 5.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF775) Suf PF05843.9 CDI77019.1 - 1.3 8.6 13.0 1.3 8.6 9.0 1.0 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) PAT1 PF09770.4 CDI77019.1 - 1.3 7.1 23.2 1.3 7.1 16.1 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Pap_E4 PF02711.9 CDI77019.1 - 1.5 9.7 8.6 1.6 9.6 6.0 1.2 1 0 0 1 1 1 0 E4 protein Herpes_DNAp_acc PF04929.7 CDI77019.1 - 1.6 7.5 9.6 1.6 7.6 6.7 1.0 1 0 0 1 1 1 0 Herpes DNA replication accessory factor DUF913 PF06025.7 CDI77019.1 - 1.8 7.2 5.4 1.6 7.3 3.7 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Presenilin PF01080.12 CDI77019.1 - 2.1 7.0 3.9 1.9 7.2 2.7 1.0 1 0 0 1 1 1 0 Presenilin Hid1 PF12722.2 CDI77019.1 - 4.6 4.7 9.0 4.4 4.8 6.3 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Serinc PF03348.10 CDI77019.1 - 4.7 5.8 10.0 4.5 5.8 6.9 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) TraH_2 PF06871.6 CDI77019.1 - 5.2 6.4 7.6 5.7 6.3 5.2 1.1 1 0 0 1 1 1 0 TraH_2 DUF106 PF01956.11 CDI77019.1 - 6.8 6.1 8.1 6.4 6.2 5.6 1.0 1 0 0 1 1 1 0 Integral membrane protein DUF106 DHHW PF14286.1 CDI77019.1 - 7.5 5.7 9.2 7.4 5.7 6.4 1.0 1 0 0 1 1 1 0 DHHW protein SGT1 PF07093.6 CDI77024.1 - 0.0022 16.4 10.3 0.0022 16.4 7.1 3.7 3 2 0 3 3 3 1 SGT1 protein RAB3GAP2_N PF14655.1 CDI77042.1 - 2.2 7.1 6.3 0.22 10.5 0.5 1.9 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus DUF4010 PF13194.1 CDI77044.1 - 0.67 9.2 2.3 6.1 6.0 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4010) Med15 PF09606.5 CDI77045.1 - 3.4e-06 25.5 113.2 4.1e-06 25.3 78.4 1.1 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal DUF3995 PF13160.1 CDI77045.1 - 1.5 8.8 4.3 0.93 9.5 1.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3995) DUF971 PF06155.7 CDI77047.1 - 0.44 11.0 0.1 0.44 11.0 0.0 3.5 4 0 0 4 4 4 0 Protein of unknown function (DUF971) PAT1 PF09770.4 CDI77047.1 - 6.3 4.9 113.8 0.14 10.3 21.6 2.1 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 Activator_LAG-3 PF11498.3 CDI77050.1 - 0.00072 18.4 38.4 0.00099 17.9 26.6 1.1 1 0 0 1 1 1 1 Transcriptional activator LAG-3 SR-25 PF10500.4 CDI77050.1 - 0.0012 18.3 1.9 0.0018 17.7 1.3 1.2 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Band_3_cyto PF07565.8 CDI77050.1 - 0.0015 18.0 4.9 0.002 17.6 3.4 1.1 1 0 0 1 1 1 1 Band 3 cytoplasmic domain SPX PF03105.14 CDI77050.1 - 0.016 14.9 5.9 0.019 14.7 4.1 1.1 1 0 0 1 1 1 0 SPX domain CDC45 PF02724.9 CDI77050.1 - 0.39 8.6 5.2 0.47 8.4 3.6 1.1 1 0 0 1 1 1 0 CDC45-like protein PAT1 PF09770.4 CDI77050.1 - 0.51 8.5 24.0 0.62 8.2 16.7 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DDHD PF02862.12 CDI77050.1 - 0.85 9.3 4.8 1.1 8.9 3.4 1.2 1 0 0 1 1 1 0 DDHD domain DUF4647 PF15504.1 CDI77050.1 - 0.92 8.2 10.7 1.1 7.9 7.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4647) DUF3994 PF13159.1 CDI77050.1 - 1.2 9.4 10.9 11 6.2 7.6 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF3994) Neur_chan_memb PF02932.11 CDI77050.1 - 1.2 8.9 4.6 1.5 8.6 3.2 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Ndc1_Nup PF09531.5 CDI77050.1 - 2.5 6.4 5.3 2.9 6.2 3.7 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup FLO_LFY PF01698.11 CDI77050.1 - 2.9 6.6 8.7 4.3 6.0 6.0 1.3 1 0 0 1 1 1 0 Floricaula / Leafy protein Rtf2 PF04641.7 CDI77050.1 - 3.9 6.6 10.9 5.9 6.0 7.6 1.2 1 0 0 1 1 1 0 Rtf2 RING-finger FRQ PF09421.5 CDI77050.1 - 5.5 4.6 10.5 7.8 4.1 7.3 1.1 1 0 0 1 1 1 0 Frequency clock protein DUF2217 PF10265.4 CDI77052.1 - 0.43 9.2 14.5 0.52 9.0 10.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) PAP1 PF08601.5 CDI77052.1 - 4.6 6.8 15.5 5.1 6.6 10.8 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 Lactamase_B_4 PF13691.1 CDI77064.1 - 0.033 13.6 0.8 0.79 9.2 0.1 2.7 3 0 0 3 3 3 0 tRNase Z endonuclease Cellulose_synt PF03552.9 CDI77064.1 - 0.049 11.9 1.4 0.074 11.3 1.0 1.2 1 0 0 1 1 1 0 Cellulose synthase Band_3_cyto PF07565.8 CDI77064.1 - 1.1 8.6 7.6 0.46 9.9 0.2 2.3 2 0 0 2 2 2 0 Band 3 cytoplasmic domain TFIIA PF03153.8 CDI77064.1 - 1.7 8.4 27.4 2.9 7.7 4.0 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Med15 PF09606.5 CDI77066.1 - 4.3e-05 21.9 23.5 4.3e-05 21.9 16.3 2.2 2 0 0 2 2 2 1 ARC105 or Med15 subunit of Mediator complex non-fungal Spore_coat_CotO PF14153.1 CDI77066.1 - 0.0043 16.5 3.3 0.0043 16.5 2.3 2.4 3 0 0 3 3 3 1 Spore coat protein CotO DUF3306 PF11748.3 CDI77066.1 - 0.088 13.4 22.0 0.59 10.8 2.8 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3306) DUF4484 PF14831.1 CDI77066.1 - 0.37 10.8 10.7 0.39 10.8 0.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4484) FHIPEP PF00771.15 CDI77066.1 - 0.46 8.7 13.8 0.29 9.3 3.4 2.1 2 0 0 2 2 2 0 FHIPEP family Apc15p PF05841.6 CDI77066.1 - 0.87 10.3 29.2 2.1 9.0 6.9 3.2 3 0 0 3 3 3 0 Apc15p protein HlyD_2 PF12700.2 CDI77066.1 - 1.9 7.5 19.6 0.089 11.9 5.0 2.2 2 0 0 2 2 2 0 HlyD family secretion protein PAT1 PF09770.4 CDI77066.1 - 2.4 6.2 52.4 0.39 8.8 10.3 2.2 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 MAT1 PF06391.8 CDI77066.1 - 2.7 7.5 29.6 2.7 7.5 5.5 2.2 2 0 0 2 2 2 0 CDK-activating kinase assembly factor MAT1 AAA_23 PF13476.1 CDI77066.1 - 2.8 8.2 28.8 0.82 9.9 4.4 2.2 2 0 0 2 2 2 0 AAA domain Bul1_N PF04425.7 CDI77066.1 - 3.4 6.1 16.5 3.4 6.1 5.7 2.1 2 0 0 2 2 2 0 Bul1 N terminus Glt_symporter PF03616.9 CDI77066.1 - 5.1 5.4 7.2 0.36 9.2 0.7 2.1 2 0 0 2 2 2 0 Sodium/glutamate symporter MRP-S26 PF14943.1 CDI77066.1 - 8.3 5.9 24.6 5.5 6.5 7.2 2.4 2 0 0 2 2 2 0 Mitochondrial ribosome subunit S26 KBP_C PF12309.3 CDI77066.1 - 8.8 5.1 23.5 1.4 7.8 8.0 2.3 2 0 0 2 2 2 0 KIF-1 binding protein C terminal TCP PF03634.8 CDI77066.1 - 9.8 6.5 29.4 5.9 7.2 6.3 3.2 3 0 0 3 3 3 0 TCP family transcription factor DUF755 PF05501.6 CDI77077.1 - 0.011 15.7 21.2 0.011 15.7 14.7 7.5 7 1 1 8 8 8 0 Domain of unknown function (DUF755) SOBP PF15279.1 CDI77092.1 - 0.1 12.9 17.9 0.14 12.5 12.4 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein Med15 PF09606.5 CDI77092.1 - 0.13 10.3 88.1 0.0075 14.5 40.6 2.0 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal SR-25 PF10500.4 CDI77092.1 - 0.61 9.5 22.9 0.0097 15.4 7.1 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein SpoIIIAH PF12685.2 CDI77092.1 - 9.5 5.6 37.5 10 5.5 8.2 2.2 1 1 1 2 2 2 0 SpoIIIAH-like protein cobW PF02492.14 CDI77109.1 - 2.6e-08 33.4 12.4 7.8e-05 22.1 1.1 3.5 2 1 1 3 3 3 2 CobW/HypB/UreG, nucleotide-binding domain SR-25 PF10500.4 CDI77109.1 - 0.0041 16.6 10.8 0.0041 16.6 7.5 5.2 4 1 0 4 4 4 1 Nuclear RNA-splicing-associated protein Transposase_20 PF02371.11 CDI77109.1 - 0.0043 17.1 1.4 0.013 15.6 0.9 1.8 1 0 0 1 1 1 1 Transposase IS116/IS110/IS902 family SprA-related PF12118.3 CDI77112.1 - 0.00051 19.4 63.4 0.0017 17.7 30.4 2.1 2 0 0 2 2 2 2 SprA-related family AAA_28 PF13521.1 CDI77112.1 - 0.0079 16.1 0.9 0.0079 16.1 0.6 2.7 2 1 0 2 2 2 1 AAA domain GAGA_bind PF06217.7 CDI77112.1 - 0.54 10.1 22.6 0.21 11.5 11.6 2.1 2 0 0 2 2 2 0 GAGA binding protein-like family DUF605 PF04652.11 CDI77112.1 - 0.85 8.9 44.7 1.2 8.4 31.0 1.2 1 0 0 1 1 1 0 Vta1 like DUF2052 PF09747.4 CDI77112.1 - 0.94 9.3 33.3 0.86 9.4 0.3 2.1 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) PAT1 PF09770.4 CDI77112.1 - 5.9 5.0 68.7 9.5 4.3 47.6 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Ycf1 PF05758.7 CDI77112.1 - 5.9 4.4 25.0 5 4.7 0.4 2.0 2 0 0 2 2 2 0 Ycf1 ATP-synt_D PF01813.12 CDI77115.1 - 4.5e-30 104.6 0.9 5.6e-30 104.3 0.6 1.2 1 0 0 1 1 1 1 ATP synthase subunit D mIF3 PF14877.1 CDI77115.1 - 0.0021 17.4 0.1 0.0025 17.2 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial translation initiation factor PAE PF03283.8 CDI77115.1 - 0.018 13.7 0.0 0.23 10.0 0.0 2.0 2 0 0 2 2 2 0 Pectinacetylesterase Med2 PF11214.3 CDI77115.1 - 0.083 12.9 0.7 0.14 12.1 0.5 1.4 1 0 0 1 1 1 0 Mediator complex subunit 2 Metallophos PF00149.23 CDI77127.1 - 2.1e-23 82.7 0.1 3.6e-23 82.0 0.1 1.3 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase DUF1180 PF06679.7 CDI77127.1 - 0.052 13.4 8.2 0.08 12.8 5.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) DUF2360 PF10152.4 CDI77127.1 - 2.1 8.6 9.7 0.86 9.8 3.0 2.1 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) ParA PF10609.4 CDI77128.1 - 0.13 12.1 0.0 0.18 11.7 0.0 1.2 1 0 0 1 1 1 0 ParA/MinD ATPase like Utp14 PF04615.8 CDI77131.1 - 1.6 6.8 79.4 1.9 6.5 55.1 1.1 1 0 0 1 1 1 0 Utp14 protein CDC27 PF09507.5 CDI77131.1 - 9.8 5.2 73.4 13 4.8 50.9 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 SR-25 PF10500.4 CDI77132.1 - 7.8e-05 22.2 8.3 0.00012 21.6 5.8 1.2 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Peptidase_S49_N PF08496.5 CDI77132.1 - 0.00015 21.6 4.3 0.00017 21.4 3.0 1.1 1 0 0 1 1 1 1 Peptidase family S49 N-terminal Pex14_N PF04695.8 CDI77132.1 - 0.00037 20.5 11.8 0.00053 20.0 8.2 1.3 1 0 0 1 1 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region T2SE PF00437.15 CDI77132.1 - 0.00073 18.5 0.2 0.00091 18.2 0.1 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_16 PF13191.1 CDI77132.1 - 0.00092 19.2 0.0 0.00092 19.2 0.0 2.1 1 1 1 2 2 1 1 AAA ATPase domain CDC73 PF05179.9 CDI77132.1 - 0.0019 17.6 4.0 0.0019 17.6 2.8 1.1 1 0 0 1 1 1 1 RNA pol II accessory factor, Cdc73 family Adeno_IVa2 PF02456.10 CDI77132.1 - 0.0039 15.8 0.2 0.0046 15.6 0.1 1.1 1 0 0 1 1 1 1 Adenovirus IVa2 protein G-alpha PF00503.15 CDI77132.1 - 0.0043 15.7 11.3 0.0052 15.5 7.8 1.1 1 0 0 1 1 1 1 G-protein alpha subunit DUF4175 PF13779.1 CDI77132.1 - 0.0083 13.8 30.5 0.0088 13.8 21.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4175) Dala_Dala_lig_N PF01820.16 CDI77132.1 - 0.0084 16.4 1.9 0.012 15.9 1.3 1.2 1 0 0 1 1 1 1 D-ala D-ala ligase N-terminus Arch_ATPase PF01637.13 CDI77132.1 - 0.0088 15.7 0.0 0.02 14.5 0.0 1.5 1 1 1 2 2 1 1 Archaeal ATPase TAF1D PF15333.1 CDI77132.1 - 0.0097 15.7 4.5 0.013 15.2 3.1 1.1 1 0 0 1 1 1 1 TATA box-binding protein-associated factor 1D AAA_19 PF13245.1 CDI77132.1 - 0.012 15.3 0.1 0.021 14.5 0.0 1.5 1 1 0 1 1 1 0 Part of AAA domain Nitroreductase PF00881.19 CDI77132.1 - 0.013 15.3 2.1 0.016 15.0 1.5 1.2 1 0 0 1 1 1 0 Nitroreductase family Spore_coat_CotO PF14153.1 CDI77132.1 - 0.017 14.5 12.8 0.019 14.4 8.9 1.1 1 0 0 1 1 1 0 Spore coat protein CotO AFG1_ATPase PF03969.11 CDI77132.1 - 0.022 13.6 3.7 0.026 13.3 2.5 1.1 1 0 0 1 1 1 0 AFG1-like ATPase cobW PF02492.14 CDI77132.1 - 0.022 14.1 0.9 0.044 13.2 0.0 1.9 2 1 0 2 2 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_29 PF13555.1 CDI77132.1 - 0.025 14.0 0.0 0.044 13.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain OATP PF03137.15 CDI77132.1 - 0.026 12.5 7.2 0.032 12.2 5.0 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Suf PF05843.9 CDI77132.1 - 0.037 13.7 12.5 0.043 13.5 8.6 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) PBP1_TM PF14812.1 CDI77132.1 - 0.039 14.2 7.9 0.063 13.5 5.5 1.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal MutS_V PF00488.16 CDI77132.1 - 0.041 13.2 0.1 0.055 12.8 0.0 1.2 1 0 0 1 1 1 0 MutS domain V Med15 PF09606.5 CDI77132.1 - 0.05 11.7 36.2 0.052 11.7 25.1 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF4366 PF14283.1 CDI77132.1 - 0.051 12.9 2.3 0.07 12.5 1.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) AAA_22 PF13401.1 CDI77132.1 - 0.057 13.5 1.5 0.12 12.5 0.0 2.0 1 1 1 2 2 1 0 AAA domain OmpH PF03938.9 CDI77132.1 - 0.062 13.2 23.4 0.074 12.9 16.2 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) PAT1 PF09770.4 CDI77132.1 - 0.062 11.5 24.8 0.064 11.4 17.2 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 AAA_14 PF13173.1 CDI77132.1 - 0.066 13.1 0.2 0.17 11.7 0.0 1.7 2 0 0 2 2 1 0 AAA domain Kei1 PF08552.6 CDI77132.1 - 0.068 12.8 3.8 0.084 12.5 2.6 1.2 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 eIF-3_zeta PF05091.7 CDI77132.1 - 0.078 11.5 10.6 0.079 11.5 7.3 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) TFIIA PF03153.8 CDI77132.1 - 0.092 12.6 17.8 0.099 12.5 12.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit FLO_LFY PF01698.11 CDI77132.1 - 0.1 11.4 8.5 0.12 11.1 5.9 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein CDK5_activator PF03261.10 CDI77132.1 - 0.1 11.8 11.6 0.12 11.6 8.1 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein Peptidase_M56 PF05569.6 CDI77132.1 - 0.1 11.5 2.3 0.14 11.1 1.6 1.1 1 0 0 1 1 1 0 BlaR1 peptidase M56 UPF0565 PF10561.4 CDI77132.1 - 0.11 11.4 4.7 0.11 11.3 3.2 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0565 Peroxin-13_N PF04088.8 CDI77132.1 - 0.12 12.3 3.3 0.18 11.7 2.3 1.2 1 0 0 1 1 1 0 Peroxin 13, N-terminal region Ycf1 PF05758.7 CDI77132.1 - 0.12 10.0 7.0 0.12 10.0 4.9 1.0 1 0 0 1 1 1 0 Ycf1 BRF1 PF07741.8 CDI77132.1 - 0.13 12.4 6.6 0.19 11.9 4.6 1.4 1 0 0 1 1 1 0 Brf1-like TBP-binding domain Peptidase_C58 PF03543.9 CDI77132.1 - 0.15 11.5 13.9 0.19 11.2 9.6 1.1 1 0 0 1 1 1 0 Yersinia/Haemophilus virulence surface antigen Folate_carrier PF01770.13 CDI77132.1 - 0.15 10.5 7.2 0.2 10.1 5.0 1.1 1 0 0 1 1 1 0 Reduced folate carrier Gti1_Pac2 PF09729.4 CDI77132.1 - 0.18 11.6 4.5 0.2 11.5 3.1 1.2 1 0 0 1 1 1 0 Gti1/Pac2 family Plasmodium_Vir PF05795.6 CDI77132.1 - 0.2 10.8 1.5 0.23 10.6 1.0 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein GNT-I PF03071.10 CDI77132.1 - 0.21 10.0 6.2 0.25 9.8 4.3 1.1 1 0 0 1 1 1 0 GNT-I family RR_TM4-6 PF06459.7 CDI77132.1 - 0.23 11.3 8.1 0.27 11.1 5.6 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Glyco_transf_15 PF01793.11 CDI77132.1 - 0.24 10.3 6.5 0.29 10.0 4.5 1.1 1 0 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase DUF2561 PF10812.3 CDI77132.1 - 0.25 10.9 1.5 0.34 10.4 1.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2561) DUF605 PF04652.11 CDI77132.1 - 0.26 10.6 13.1 0.27 10.6 9.0 1.1 1 0 0 1 1 1 0 Vta1 like E3_UbLigase_R4 PF13764.1 CDI77132.1 - 0.29 8.9 6.8 0.36 8.6 4.7 1.1 1 0 0 1 1 1 0 E3 ubiquitin-protein ligase UBR4 DUF3474 PF11960.3 CDI77132.1 - 0.36 10.8 1.9 0.43 10.5 1.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3474) LMBR1 PF04791.11 CDI77132.1 - 0.43 9.1 2.0 0.41 9.1 1.4 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein SprA-related PF12118.3 CDI77132.1 - 0.47 9.7 31.6 0.65 9.2 21.9 1.2 1 0 0 1 1 1 0 SprA-related family Ctr PF04145.10 CDI77132.1 - 0.49 10.4 5.8 0.63 10.0 4.1 1.2 1 0 0 1 1 1 0 Ctr copper transporter family AAA_23 PF13476.1 CDI77132.1 - 0.51 10.6 19.4 37 4.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain Glt_symporter PF03616.9 CDI77132.1 - 0.53 8.7 2.8 0.68 8.3 2.0 1.2 1 0 0 1 1 1 0 Sodium/glutamate symporter DUF2048 PF09752.4 CDI77132.1 - 0.58 8.9 5.3 0.75 8.5 3.7 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2048) FHIPEP PF00771.15 CDI77132.1 - 0.6 8.3 6.0 0.63 8.3 4.1 1.1 1 0 0 1 1 1 0 FHIPEP family Gag_spuma PF03276.9 CDI77132.1 - 0.61 8.3 29.3 18 3.4 0.0 2.0 2 0 0 2 2 2 0 Spumavirus gag protein SeqA PF03925.8 CDI77132.1 - 0.7 9.5 10.2 0.97 9.0 7.0 1.2 1 0 0 1 1 1 0 SeqA protein AAA PF00004.24 CDI77132.1 - 0.71 10.0 0.0 0.71 10.0 0.0 2.3 2 1 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 CDI77132.1 - 0.73 9.7 12.2 1.2 9.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain DUF912 PF06024.7 CDI77132.1 - 0.84 9.7 8.4 1.6 8.8 5.8 1.5 1 1 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF106 PF01956.11 CDI77132.1 - 0.98 8.9 6.7 1.1 8.8 4.6 1.1 1 0 0 1 1 1 0 Integral membrane protein DUF106 DUF1800 PF08811.6 CDI77132.1 - 1.1 8.1 13.6 1.2 7.9 9.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1800) DUF2126 PF09899.4 CDI77132.1 - 1.2 7.0 7.9 1.4 6.8 5.5 1.0 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) DUF2072 PF09845.4 CDI77132.1 - 1.3 8.9 5.9 1.9 8.4 4.1 1.2 1 0 0 1 1 1 0 Zn-ribbon containing protein (DUF2072) Neur_chan_memb PF02932.11 CDI77132.1 - 1.3 8.8 5.1 1.5 8.6 3.5 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region AIF_C PF14721.1 CDI77132.1 - 1.4 9.1 8.7 2 8.6 6.1 1.2 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Cas1_AcylT PF07779.7 CDI77132.1 - 1.4 7.2 7.2 1.9 6.8 5.0 1.0 1 0 0 1 1 1 0 10 TM Acyl Transferase domain found in Cas1p ABC_tran PF00005.22 CDI77132.1 - 1.7 8.9 0.0 1.7 8.9 0.0 2.1 1 1 1 2 2 1 0 ABC transporter DUF1764 PF08576.5 CDI77132.1 - 1.8 9.3 13.1 2.7 8.7 9.1 1.3 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) Peptidase_U57 PF05582.7 CDI77132.1 - 1.9 7.4 9.6 2.7 6.8 6.7 1.2 1 0 0 1 1 1 0 YabG peptidase U57 DUF2232 PF09991.4 CDI77132.1 - 1.9 7.4 4.9 2.3 7.1 3.4 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) Cellulose_synt PF03552.9 CDI77132.1 - 2.1 6.5 3.8 2.1 6.5 2.6 1.0 1 0 0 1 1 1 0 Cellulose synthase Paramyxo_ncap PF00973.14 CDI77132.1 - 2.1 6.9 7.6 2.2 6.8 5.2 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein PAF-AH_p_II PF03403.8 CDI77132.1 - 2.2 6.4 10.1 2.7 6.1 7.0 1.1 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II Raftlin PF15250.1 CDI77132.1 - 2.3 6.6 13.9 2.6 6.4 9.6 1.1 1 0 0 1 1 1 0 Raftlin Serinc PF03348.10 CDI77132.1 - 2.3 6.8 12.2 3.3 6.3 8.4 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) Fes1 PF08609.5 CDI77132.1 - 2.4 8.6 7.4 11 6.5 5.2 1.9 1 1 0 1 1 1 0 Nucleotide exchange factor Fes1 EIIBC-GUT_N PF03612.9 CDI77132.1 - 2.5 7.6 8.4 4.5 6.8 5.8 1.4 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus DUF4407 PF14362.1 CDI77132.1 - 2.6 6.9 15.8 3.2 6.6 10.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) RED_N PF07808.8 CDI77132.1 - 2.8 7.0 17.8 3.8 6.6 12.3 1.2 1 0 0 1 1 1 0 RED-like protein N-terminal region Herpes_DNAp_acc PF04929.7 CDI77132.1 - 2.9 6.7 11.3 3.9 6.3 7.8 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Spc7_N PF15402.1 CDI77132.1 - 3.5 5.5 18.7 4.4 5.1 12.9 1.0 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 YABBY PF04690.8 CDI77132.1 - 3.5 7.8 9.3 4.7 7.4 6.4 1.2 1 0 0 1 1 1 0 YABBY protein AAA_28 PF13521.1 CDI77132.1 - 3.7 7.4 0.0 3.7 7.4 0.0 2.3 2 0 0 2 2 1 0 AAA domain DDHD PF02862.12 CDI77132.1 - 3.7 7.2 13.0 5.2 6.8 9.0 1.1 1 0 0 1 1 1 0 DDHD domain GOLD_2 PF13897.1 CDI77132.1 - 3.9 7.7 6.7 6.1 7.0 4.7 1.3 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking DUF4557 PF15101.1 CDI77132.1 - 3.9 7.2 22.8 5.1 6.8 15.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) FimP PF09766.4 CDI77132.1 - 4.6 6.2 24.6 6.1 5.8 17.0 1.1 1 0 0 1 1 1 0 Fms-interacting protein P5-ATPase PF12409.3 CDI77132.1 - 4.7 7.0 10.4 6.8 6.5 7.2 1.2 1 0 0 1 1 1 0 P5-type ATPase cation transporter KAP_NTPase PF07693.9 CDI77132.1 - 4.7 6.0 0.0 4.7 6.0 0.0 2.1 1 1 1 2 2 1 0 KAP family P-loop domain Miro PF08477.8 CDI77132.1 - 4.8 7.7 0.0 4.8 7.7 0.0 2.2 1 1 1 2 2 1 0 Miro-like protein Anoctamin PF04547.7 CDI77132.1 - 5.2 5.5 8.0 5.9 5.4 5.5 1.1 1 0 0 1 1 1 0 Calcium-activated chloride channel DUF3675 PF12428.3 CDI77132.1 - 6.2 7.1 5.6 10 6.4 3.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3675) PEX11 PF05648.9 CDI77132.1 - 7 5.8 8.5 12 5.1 5.9 1.4 1 0 0 1 1 1 0 Peroxisomal biogenesis factor 11 (PEX11) Sec62 PF03839.11 CDI77132.1 - 8.2 5.7 9.2 13 5.1 6.3 1.3 1 0 0 1 1 1 0 Translocation protein Sec62 DHHW PF14286.1 CDI77132.1 - 9.9 5.3 8.7 12 5.0 6.1 1.1 1 0 0 1 1 1 0 DHHW protein DXP_synthase_N PF13292.1 CDI77133.1 - 2.2e-37 128.4 0.1 2.2e-37 128.4 0.1 3.4 4 0 0 4 4 4 1 1-deoxy-D-xylulose-5-phosphate synthase Transket_pyr PF02779.19 CDI77133.1 - 1.3e-28 99.7 0.1 5.3e-28 97.7 0.1 2.1 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain SAPS PF04499.10 CDI77133.1 - 0.65 8.5 30.0 0.031 12.9 0.0 3.5 2 1 0 2 2 2 0 SIT4 phosphatase-associated protein Fumble PF03630.9 CDI77134.1 - 0.008 15.0 0.0 0.008 15.0 0.0 5.6 2 1 4 6 6 6 2 Fumble DUF1757 PF08560.5 CDI77134.1 - 0.078 12.6 4.4 0.043 13.5 1.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1757) RAP1 PF07218.6 CDI77134.1 - 6.2 4.7 30.7 0.057 11.5 5.4 2.2 2 0 0 2 2 2 0 Rhoptry-associated protein 1 (RAP-1) Abhydrolase_6 PF12697.2 CDI77154.1 - 1.5e-06 28.2 2.8 1.5e-06 28.2 1.9 3.1 2 1 0 2 2 2 1 Alpha/beta hydrolase family Rpp20 PF12328.3 CDI77154.1 - 0.017 14.8 0.5 0.017 14.8 0.3 2.1 2 0 0 2 2 2 0 Rpp20 subunit of nuclear RNase MRP and P DUF3276 PF11680.3 CDI77154.1 - 0.64 9.8 4.7 0.16 11.7 0.9 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3276) Vma12 PF11712.3 CDI77154.1 - 0.97 9.1 8.3 0.31 10.7 0.2 2.5 2 0 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Suf PF05843.9 CDI77154.1 - 1.1 8.9 10.6 0.45 10.2 1.1 2.3 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) DUF1510 PF07423.6 CDI77156.1 - 0.00052 19.4 4.9 0.001 18.4 3.4 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1510) DUF1469 PF07332.6 CDI77156.1 - 0.068 12.9 4.9 0.26 11.0 1.0 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1469) DUF1109 PF06532.6 CDI77156.1 - 0.074 12.4 7.9 0.074 12.4 0.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1109) Ycf1 PF05758.7 CDI77156.1 - 0.12 10.0 0.1 0.13 9.9 0.1 1.1 1 0 0 1 1 1 0 Ycf1 DUF92 PF01940.11 CDI77156.1 - 0.15 11.2 1.9 0.75 8.9 0.3 2.2 2 0 0 2 2 2 0 Integral membrane protein DUF92 Cwf_Cwc_15 PF04889.7 CDI77156.1 - 0.2 11.3 13.7 0.24 11.1 9.5 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF2782 PF11191.3 CDI77156.1 - 1.6 8.7 10.8 1.4 8.9 2.6 2.9 1 1 0 2 2 2 0 Protein of unknown function (DUF2782) PsbW PF07123.7 CDI77156.1 - 2.5 8.1 10.3 0.63 10.0 4.6 1.8 2 0 0 2 2 2 0 Photosystem II reaction centre W protein (PsbW) Trp_oprn_chp PF09534.5 CDI77156.1 - 3.4 7.2 19.3 0.33 10.5 0.5 2.1 1 1 1 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) RskA PF10099.4 CDI77156.1 - 6 6.5 23.9 2.3 7.9 8.4 2.8 1 1 2 3 3 3 0 Anti-sigma-K factor rskA Med3 PF11593.3 CDI77156.1 - 7.4 5.6 7.4 11 5.0 5.2 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DUF3138 PF11336.3 CDI77156.1 - 8.3 4.4 6.9 11 4.0 4.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) TRAP_alpha PF03896.11 CDI77185.1 - 0.0052 15.8 4.4 0.033 13.2 0.2 3.4 4 0 0 4 4 4 1 Translocon-associated protein (TRAP), alpha subunit DUF755 PF05501.6 CDI77185.1 - 0.021 14.8 10.3 0.021 14.8 7.1 7.6 5 2 2 7 7 7 0 Domain of unknown function (DUF755) RIC3 PF15361.1 CDI77185.1 - 6.5 6.9 33.3 6.7 6.9 2.6 5.1 5 0 0 5 5 5 0 Resistance to inhibitors of cholinesterase homologue 3 Suf PF05843.9 CDI77196.1 - 0.0029 17.3 11.2 0.003 17.3 7.8 1.2 1 0 0 1 1 1 1 Suppressor of forked protein (Suf) Trypan_glycop_C PF10659.4 CDI77196.1 - 0.018 15.3 4.3 0.027 14.7 3.0 1.3 1 0 0 1 1 1 0 Trypanosome variant surface glycoprotein C-terminal domain FLO_LFY PF01698.11 CDI77196.1 - 0.019 13.8 6.8 0.025 13.4 4.7 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein zf-DHHC PF01529.15 CDI77196.1 - 0.029 13.7 0.3 0.026 13.9 0.2 1.1 1 0 0 1 1 1 0 DHHC palmitoyltransferase NARP1 PF12569.3 CDI77196.1 - 0.099 11.3 8.8 0.13 11.0 6.1 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DUF4557 PF15101.1 CDI77196.1 - 0.12 12.1 20.1 0.17 11.7 13.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) Neur_chan_memb PF02932.11 CDI77196.1 - 0.21 11.4 2.2 0.2 11.4 1.5 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region RR_TM4-6 PF06459.7 CDI77196.1 - 0.21 11.4 12.9 0.27 11.0 8.9 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Band_3_cyto PF07565.8 CDI77196.1 - 0.25 10.8 8.9 0.31 10.5 6.2 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Agouti PF05039.7 CDI77196.1 - 0.25 11.7 6.6 0.44 10.9 4.5 1.4 1 0 0 1 1 1 0 Agouti protein Stig1 PF04885.8 CDI77196.1 - 0.26 11.4 6.1 0.37 10.9 4.3 1.2 1 0 0 1 1 1 0 Stigma-specific protein, Stig1 DUF3675 PF12428.3 CDI77196.1 - 0.28 11.4 4.1 0.41 10.9 2.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3675) Zip PF02535.17 CDI77196.1 - 0.4 9.6 1.2 0.42 9.5 0.8 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Glyco_transf_15 PF01793.11 CDI77196.1 - 0.45 9.3 6.6 0.56 9.1 4.6 1.0 1 0 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase DUF913 PF06025.7 CDI77196.1 - 0.56 8.9 6.2 0.7 8.5 4.3 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) FimP PF09766.4 CDI77196.1 - 0.68 8.9 24.1 0.86 8.6 16.7 1.1 1 0 0 1 1 1 0 Fms-interacting protein OATP PF03137.15 CDI77196.1 - 0.79 7.6 7.3 0.91 7.4 5.1 1.0 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Med15 PF09606.5 CDI77196.1 - 0.95 7.5 54.6 1.2 7.2 37.8 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF3043 PF11241.3 CDI77196.1 - 1.1 8.7 7.5 1.9 8.0 5.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) FAM176 PF14851.1 CDI77196.1 - 1.5 8.4 4.4 2.2 7.9 3.1 1.2 1 0 0 1 1 1 0 FAM176 family AUX_IAA PF02309.11 CDI77196.1 - 1.6 8.3 10.0 2.2 7.9 7.0 1.2 1 0 0 1 1 1 0 AUX/IAA family DUF1675 PF07897.6 CDI77196.1 - 1.6 8.4 9.8 2.2 8.0 6.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) Ndc1_Nup PF09531.5 CDI77196.1 - 1.9 6.7 7.0 1.9 6.7 4.9 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Ycf1 PF05758.7 CDI77196.1 - 2.2 5.9 9.1 2.5 5.7 6.3 1.0 1 0 0 1 1 1 0 Ycf1 MDFI PF15316.1 CDI77196.1 - 2.5 8.0 7.9 4.3 7.3 5.5 1.4 1 0 0 1 1 1 0 MyoD family inhibitor DDHD PF02862.12 CDI77196.1 - 2.9 7.6 11.1 3.9 7.2 7.7 1.1 1 0 0 1 1 1 0 DDHD domain Presenilin PF01080.12 CDI77196.1 - 3.3 6.4 8.9 4.5 5.9 6.1 1.2 1 0 0 1 1 1 0 Presenilin DUF3464 PF11947.3 CDI77196.1 - 3.4 7.1 9.0 6 6.3 6.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) Spore_coat_CotO PF14153.1 CDI77196.1 - 4.3 6.7 19.0 5.7 6.3 13.2 1.1 1 0 0 1 1 1 0 Spore coat protein CotO CPSF100_C PF13299.1 CDI77196.1 - 4.8 7.3 10.0 7.6 6.6 6.9 1.3 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal DUF4175 PF13779.1 CDI77196.1 - 5.9 4.4 37.3 10 3.6 25.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) DUF775 PF05603.7 CDI77196.1 - 6.9 6.1 13.6 10 5.5 9.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF775) UPF0560 PF10577.4 CDI77196.1 - 6.9 4.7 20.3 8.4 4.5 14.1 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Peptidase_U57 PF05582.7 CDI77196.1 - 8.8 5.2 8.1 11 4.8 5.6 1.1 1 0 0 1 1 1 0 YabG peptidase U57 Folate_carrier PF01770.13 CDI77196.1 - 9.8 4.5 7.1 12 4.2 4.9 1.1 1 0 0 1 1 1 0 Reduced folate carrier Pox_Ag35 PF03286.9 CDI77197.1 - 0.63 9.5 25.9 0.62 9.5 18.0 1.0 1 0 0 1 1 1 0 Pox virus Ag35 surface protein SR-25 PF10500.4 CDI77197.1 - 0.94 8.8 30.2 1.1 8.6 20.9 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein TT_ORF2 PF02957.10 CDI77197.1 - 1.3 9.7 6.7 1.5 9.5 4.7 1.0 1 0 0 1 1 1 0 TT viral ORF2 CENP-B_dimeris PF09026.5 CDI77197.1 - 2.4 8.4 6.1 2.5 8.4 4.0 1.3 1 1 0 1 1 1 0 Centromere protein B dimerisation domain Adaptin_binding PF10199.4 CDI77197.1 - 4.1 7.6 14.2 4.5 7.5 9.8 1.0 1 0 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 PSK PF06404.7 CDI77197.1 - 7.7 7.3 11.7 11 6.8 8.1 1.2 1 0 0 1 1 1 0 Phytosulfokine precursor protein (PSK) CDC27 PF09507.5 CDI77197.1 - 7.8 5.6 27.8 8.1 5.5 19.3 1.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 DUF2029 PF09594.5 CDI77213.1 - 0.00096 18.7 6.7 0.038 13.5 2.8 2.3 2 1 0 2 2 2 2 Protein of unknown function (DUF2029) DUF4407 PF14362.1 CDI77213.1 - 2 7.2 37.1 3 6.7 25.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Med15 PF09606.5 CDI77213.1 - 2.2 6.3 81.2 2.9 5.9 56.3 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal RskA PF10099.4 CDI77213.1 - 7.1 6.3 38.8 7.5 6.2 14.6 2.6 2 1 1 3 3 3 0 Anti-sigma-K factor rskA Med3 PF11593.3 CDI77222.1 - 0.74 8.9 24.5 0.86 8.7 17.0 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal FAP PF07174.6 CDI77222.1 - 1.7 7.8 32.2 2.6 7.2 22.3 1.3 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) CAF-1_p150 PF11600.3 CDI77224.1 - 4.8e-05 22.8 28.6 5.1e-05 22.7 19.9 1.0 1 0 0 1 1 1 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal Corona_nucleoca PF00937.13 CDI77224.1 - 0.2 10.5 34.8 0.22 10.4 24.1 1.0 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein DUF3801 PF12687.2 CDI77224.1 - 0.3 10.6 14.8 0.37 10.3 10.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3801) SprA-related PF12118.3 CDI77224.1 - 0.45 9.8 43.3 0.53 9.5 30.0 1.1 1 0 0 1 1 1 0 SprA-related family AAA_23 PF13476.1 CDI77224.1 - 0.64 10.3 13.3 0.85 9.9 9.2 1.2 1 0 0 1 1 1 0 AAA domain Suf PF05843.9 CDI77224.1 - 1.2 8.7 27.8 1.4 8.6 19.3 1.0 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Nop53 PF07767.6 CDI77224.1 - 1.3 7.9 20.1 1.5 7.7 14.0 1.0 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) eIF3_subunit PF08597.5 CDI77224.1 - 1.5 8.3 16.9 1.6 8.2 11.7 1.1 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit OmpH PF03938.9 CDI77224.1 - 3.9 7.4 27.9 4.3 7.2 19.3 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) SOBP PF15279.1 CDI77224.1 - 4 7.7 24.8 4.6 7.5 17.2 1.0 1 0 0 1 1 1 0 Sine oculis-binding protein RAP1 PF07218.6 CDI77224.1 - 4.4 5.2 15.3 4.8 5.1 10.6 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Med15 PF09606.5 CDI77224.1 - 6.1 4.9 39.7 7 4.7 27.5 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Herpes_DNAp_acc PF04929.7 CDI77224.1 - 6.3 5.6 23.7 6.2 5.6 16.4 1.0 1 0 0 1 1 1 0 Herpes DNA replication accessory factor DUF2229 PF09989.4 CDI77224.1 - 6.7 6.0 6.7 7.2 5.9 4.6 1.1 1 0 0 1 1 1 0 CoA enzyme activase uncharacterised domain (DUF2229) DUF2890 PF11081.3 CDI77224.1 - 9.2 6.2 20.7 11 5.9 14.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) Prenyltrans_2 PF13249.1 CDI77225.1 - 0.35 11.2 5.9 0.49 10.8 0.2 2.4 1 1 1 2 2 2 0 Prenyltransferase-like LZ_Tnp_IS66 PF13007.2 CDI77225.1 - 7 7.3 11.5 12 6.6 1.2 2.4 2 0 0 2 2 2 0 Transposase C of IS166 homeodomain DUF2215 PF10225.4 CDI77260.1 - 0.0081 15.6 5.3 0.0094 15.4 3.7 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2215) Ribonuc_P_40 PF08584.6 CDI77260.1 - 0.042 12.8 3.6 0.054 12.4 2.5 1.1 1 0 0 1 1 1 0 Ribonuclease P 40kDa (Rpp40) subunit DUF4175 PF13779.1 CDI77260.1 - 0.089 10.4 33.4 0.091 10.4 23.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Folliculin PF11704.3 CDI77260.1 - 0.2 11.2 7.3 0.23 11.0 5.1 1.2 1 0 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport UvrD_C PF13361.1 CDI77260.1 - 0.24 10.7 8.6 0.26 10.7 6.0 1.0 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain Hid1 PF12722.2 CDI77260.1 - 0.33 8.6 9.9 0.33 8.5 6.8 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein AMP-binding PF00501.23 CDI77260.1 - 0.33 9.2 2.6 0.35 9.1 1.8 1.0 1 0 0 1 1 1 0 AMP-binding enzyme Draxin PF15550.1 CDI77260.1 - 0.41 10.2 6.7 0.42 10.2 4.6 1.0 1 0 0 1 1 1 0 Draxin DUF3449 PF11931.3 CDI77260.1 - 0.43 10.0 9.5 0.45 9.9 6.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3449) Prismane PF03063.15 CDI77260.1 - 0.48 8.7 4.3 0.54 8.5 3.0 1.0 1 0 0 1 1 1 0 Prismane/CO dehydrogenase family Peptidase_S49_N PF08496.5 CDI77260.1 - 0.5 10.1 10.0 0.59 9.9 6.9 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal AIF_C PF14721.1 CDI77260.1 - 0.67 10.2 3.7 0.75 10.0 2.6 1.3 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Band_3_cyto PF07565.8 CDI77260.1 - 0.67 9.4 10.6 0.73 9.3 7.3 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Serinc PF03348.10 CDI77260.1 - 0.8 8.3 5.9 0.79 8.3 4.1 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) Phage_GPO PF05929.6 CDI77260.1 - 1.1 8.5 13.4 1.2 8.3 9.3 1.1 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase Bac_GDH PF05088.7 CDI77260.1 - 1.1 6.5 11.7 1.1 6.4 8.1 1.0 1 0 0 1 1 1 0 Bacterial NAD-glutamate dehydrogenase DDHD PF02862.12 CDI77260.1 - 1.2 8.8 8.3 1.4 8.6 5.7 1.1 1 0 0 1 1 1 0 DDHD domain DUF4446 PF14584.1 CDI77260.1 - 1.7 8.4 9.1 2.1 8.1 6.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) SID-1_RNA_chan PF13965.1 CDI77260.1 - 1.7 6.6 4.0 1.8 6.6 2.8 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 AAA_11 PF13086.1 CDI77260.1 - 1.8 8.1 13.6 2.1 7.8 9.5 1.1 1 0 0 1 1 1 0 AAA domain Gag_spuma PF03276.9 CDI77260.1 - 2 6.6 20.1 2.2 6.5 13.9 1.1 1 0 0 1 1 1 0 Spumavirus gag protein Peptidase_U57 PF05582.7 CDI77260.1 - 2.1 7.2 6.6 2.3 7.1 4.6 1.1 1 0 0 1 1 1 0 YabG peptidase U57 YABBY PF04690.8 CDI77260.1 - 2.2 8.5 8.0 2.6 8.2 5.5 1.2 1 0 0 1 1 1 0 YABBY protein RE_TdeIII PF09520.5 CDI77260.1 - 2.2 7.5 11.9 2.6 7.2 8.3 1.2 1 0 0 1 1 1 0 Type II restriction endonuclease, TdeIII PAT1 PF09770.4 CDI77260.1 - 2.2 6.4 33.5 2.5 6.2 23.2 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Bestrophin PF01062.16 CDI77260.1 - 2.4 7.0 8.1 2.7 6.8 5.6 1.1 1 0 0 1 1 1 0 Bestrophin, RFP-TM, chloride channel Baculo_PP31 PF05311.6 CDI77260.1 - 2.6 7.2 9.1 2.9 7.0 6.3 1.1 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) Hom_end_hint PF05203.11 CDI77260.1 - 3.1 7.4 6.3 3.8 7.1 4.4 1.2 1 0 0 1 1 1 0 Hom_end-associated Hint DUF1764 PF08576.5 CDI77260.1 - 3.4 8.4 10.1 4.6 8.0 7.0 1.3 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) Peptidase_S15 PF02129.13 CDI77260.1 - 3.7 6.8 7.6 4.2 6.7 5.3 1.1 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) APG6 PF04111.7 CDI77260.1 - 5.8 5.8 19.8 6.8 5.6 13.7 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 Rpp20 PF12328.3 CDI77260.1 - 6 6.5 12.1 8.2 6.0 8.4 1.3 1 0 0 1 1 1 0 Rpp20 subunit of nuclear RNase MRP and P DUF342 PF03961.8 CDI77260.1 - 6.7 5.0 9.7 7 4.9 6.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) AAA_23 PF13476.1 CDI77260.1 - 7.1 6.9 23.8 8.1 6.7 16.5 1.1 1 0 0 1 1 1 0 AAA domain Med15 PF09606.5 CDI77260.1 - 8.1 4.4 45.6 9.2 4.3 31.6 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal OATP PF03137.15 CDI77260.1 - 8.8 4.2 6.8 8.9 4.2 4.7 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Anoctamin PF04547.7 CDI77260.1 - 9.3 4.7 9.0 11 4.5 6.2 1.0 1 0 0 1 1 1 0 Calcium-activated chloride channel Endonuc_Holl PF10107.4 CDI77260.1 - 9.3 5.9 15.3 12 5.5 10.6 1.2 1 0 0 1 1 1 0 Endonuclease related to archaeal Holliday junction resolvase HAUS6_N PF14661.1 CDI77260.1 - 9.9 5.4 19.2 11 5.2 13.3 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus SHMT PF00464.14 CDI77276.1 - 2.5e-167 556.2 0.0 5.7e-91 304.8 0.0 2.1 1 1 1 2 2 2 2 Serine hydroxymethyltransferase zf-DNA_Pol PF08996.5 CDI77281.1 - 0.03 13.6 6.2 0.045 13.0 4.3 1.3 1 0 0 1 1 1 0 DNA Polymerase alpha zinc finger Spt20 PF12090.3 CDI77281.1 - 0.035 13.4 4.9 0.037 13.3 3.4 1.1 1 0 0 1 1 1 0 Spt20 family DUF4094 PF13334.1 CDI77281.1 - 0.1 12.9 4.6 0.12 12.7 3.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4094) Serinc PF03348.10 CDI77281.1 - 0.41 9.2 3.7 0.44 9.1 2.6 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) Suf PF05843.9 CDI77281.1 - 0.72 9.5 8.8 0.82 9.3 6.1 1.0 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DivIC PF04977.10 CDI77281.1 - 2.3 7.7 14.8 2.9 7.4 10.3 1.2 1 0 0 1 1 1 0 Septum formation initiator Med15 PF09606.5 CDI77281.1 - 2.5 6.1 29.0 2.8 6.0 20.1 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF2232 PF09991.4 CDI77281.1 - 3.3 6.6 6.2 4 6.3 4.3 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) DUF4557 PF15101.1 CDI77281.1 - 3.9 7.2 13.5 4 7.2 9.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) Gag_spuma PF03276.9 CDI77281.1 - 4.1 5.6 14.2 4.5 5.4 9.8 1.0 1 0 0 1 1 1 0 Spumavirus gag protein DUF4199 PF13858.1 CDI77281.1 - 4.7 7.0 4.9 6 6.7 3.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) BAF1_ABF1 PF04684.8 CDI77281.1 - 7.3 5.3 28.7 7.5 5.2 19.9 1.0 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor SHR3_chaperone PF08229.6 CDI77281.1 - 7.4 5.4 10.5 9 5.1 7.3 1.1 1 0 0 1 1 1 0 ER membrane protein SH3 YfhO PF09586.5 CDI77301.1 - 0.00098 17.2 0.8 0.0011 17.1 0.6 1.0 1 0 0 1 1 1 1 Bacterial membrane protein YfhO BPD_transp_2 PF02653.11 CDI77301.1 - 0.0024 16.8 3.4 0.0039 16.1 2.4 1.3 1 0 0 1 1 1 1 Branched-chain amino acid transport system / permease component Bax1-I PF01027.15 CDI77301.1 - 0.048 13.2 0.6 0.06 12.9 0.4 1.2 1 0 0 1 1 1 0 Inhibitor of apoptosis-promoting Bax1 Suf PF05843.9 CDI77301.1 - 0.052 13.2 2.8 0.061 13.0 2.0 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) AAA_23 PF13476.1 CDI77301.1 - 0.23 11.7 8.8 0.24 11.7 6.1 1.1 1 0 0 1 1 1 0 AAA domain Peptidase_U57 PF05582.7 CDI77301.1 - 0.31 9.9 2.3 0.41 9.5 1.6 1.1 1 0 0 1 1 1 0 YabG peptidase U57 Endonuc_Holl PF10107.4 CDI77301.1 - 0.58 9.8 9.6 0.92 9.1 6.7 1.2 1 0 0 1 1 1 0 Endonuclease related to archaeal Holliday junction resolvase DUF4446 PF14584.1 CDI77301.1 - 0.84 9.4 4.8 1.6 8.5 3.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) DUF2149 PF09919.4 CDI77301.1 - 4.2 7.5 7.1 6.9 6.8 4.9 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2149) Kei1 PF08552.6 CDI77301.1 - 4.5 6.8 7.3 8.8 5.9 1.0 2.1 2 0 0 2 2 2 0 Inositolphosphorylceramide synthase subunit Kei1 DUF4131 PF13567.1 CDI77301.1 - 8.8 5.6 18.3 69 2.7 12.7 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4131) Helicase_C PF00271.26 CDI77308.1 - 5.1e-23 80.7 0.0 9e-23 79.9 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF966 PF06136.8 CDI77308.1 - 0.19 11.1 6.9 0.21 10.9 4.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Cluap1 PF10234.4 CDI77309.1 - 5.1e-06 25.8 0.1 5.1e-06 25.8 0.1 2.7 2 2 0 3 3 3 1 Clusterin-associated protein-1 YebG PF07130.7 CDI77309.1 - 0.49 10.1 3.1 1.3 8.7 0.3 3.0 4 0 0 4 4 4 0 YebG protein Peptidase_C15 PF01470.12 CDI77310.1 - 2.1e-16 60.3 0.0 2.4e-11 43.8 0.0 2.2 2 0 0 2 2 2 2 Pyroglutamyl peptidase RNA_pol PF00940.14 CDI77312.1 - 6.4e-130 433.2 0.0 6.4e-130 433.2 0.0 3.5 4 2 0 4 4 4 1 DNA-dependent RNA polymerase RPOL_N PF14700.1 CDI77312.1 - 1e-20 74.2 2.9 8.4e-13 48.2 0.6 8.3 6 3 2 8 8 8 3 DNA-directed RNA polymerase N-terminal Pex14_N PF04695.8 CDI77312.1 - 0.025 14.6 0.2 0.025 14.6 0.1 13.7 8 3 2 10 10 10 0 Peroxisomal membrane anchor protein (Pex14p) conserved region YgbB PF02542.11 CDI77313.1 - 2.9e-42 144.1 1.4 3.7e-42 143.8 0.9 1.1 1 0 0 1 1 1 1 YgbB family SR-25 PF10500.4 CDI77313.1 - 0.17 11.3 9.6 0.24 10.8 6.6 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein CD99L2 PF12301.3 CDI77322.1 - 0.033 13.8 8.7 0.55 9.9 4.6 2.7 1 1 1 2 2 2 0 CD99 antigen like protein 2 Spt20 PF12090.3 CDI77322.1 - 0.091 12.0 14.0 0.052 12.8 1.4 2.2 2 0 0 2 2 2 0 Spt20 family DUF1632 PF07857.7 CDI77322.1 - 0.17 11.0 0.0 0.17 11.0 0.0 1.5 2 0 0 2 2 2 0 CEO family (DUF1632) Flavodoxin_NdrI PF07972.6 CDI77322.1 - 0.22 11.4 1.9 0.38 10.6 0.3 1.9 2 0 0 2 2 2 0 NrdI Flavodoxin like DUF4366 PF14283.1 CDI77322.1 - 0.23 10.8 5.3 0.18 11.1 1.7 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4366) Med15 PF09606.5 CDI77322.1 - 1.6 6.8 50.4 2.2 6.3 35.0 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Pap_E4 PF02711.9 CDI77322.1 - 2.2 9.1 9.4 14 6.5 0.3 2.5 2 0 0 2 2 2 0 E4 protein TFIIA PF03153.8 CDI77322.1 - 2.6 7.8 30.4 4 7.2 21.1 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Neur_chan_memb PF02932.11 CDI77322.1 - 2.8 7.7 9.4 4.1 7.2 6.5 1.4 1 1 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region OATP PF03137.15 CDI77322.1 - 5.6 4.8 7.9 0.72 7.8 0.7 2.0 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family FimP PF09766.4 CDI77322.1 - 6.5 5.7 23.6 0.13 11.2 4.5 2.3 2 0 0 2 2 2 0 Fms-interacting protein DUF912 PF06024.7 CDI77322.1 - 7.3 6.7 10.1 2.6 8.1 1.5 2.4 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Parvo_coat PF00740.13 CDI77322.1 - 9.6 5.0 13.3 11 4.8 9.2 1.1 1 0 0 1 1 1 0 Parvovirus coat protein VP2 SGT1 PF07093.6 CDI77334.1 - 1.6 7.0 49.0 0.038 12.3 27.3 2.3 2 0 0 2 2 2 0 SGT1 protein SR-25 PF10500.4 CDI77341.1 - 5.1e-05 22.8 16.9 5.1e-05 22.8 11.7 4.8 3 1 1 4 4 4 2 Nuclear RNA-splicing-associated protein Zip PF02535.17 CDI77341.1 - 2.7 6.9 17.1 0.054 12.4 3.1 2.7 2 0 0 2 2 2 0 ZIP Zinc transporter SprA-related PF12118.3 CDI77346.1 - 0.015 14.6 15.1 0.021 14.1 10.5 1.2 1 0 0 1 1 1 0 SprA-related family Pex14_N PF04695.8 CDI77346.1 - 0.023 14.7 17.4 0.042 13.9 12.1 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF737 PF05300.6 CDI77346.1 - 0.051 13.5 8.1 0.06 13.2 5.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF737) DUF4557 PF15101.1 CDI77346.1 - 0.053 13.3 9.2 0.06 13.1 6.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) Suf PF05843.9 CDI77346.1 - 0.06 13.0 10.2 0.062 13.0 7.1 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Baculo_PP31 PF05311.6 CDI77346.1 - 0.081 12.1 4.5 0.089 12.0 3.1 1.0 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) Corona_nucleoca PF00937.13 CDI77346.1 - 0.082 11.8 13.2 0.089 11.7 9.2 1.1 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein FLO_LFY PF01698.11 CDI77346.1 - 0.082 11.7 3.1 0.088 11.6 2.1 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein FNIP_N PF14636.1 CDI77346.1 - 0.084 13.3 9.9 0.1 13.0 6.9 1.1 1 0 0 1 1 1 0 Folliculin-interacting protein N-terminus CAF-1_p150 PF11600.3 CDI77346.1 - 0.091 12.1 16.7 0.11 11.8 11.6 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal CDC45 PF02724.9 CDI77346.1 - 0.11 10.5 6.7 0.13 10.3 4.6 1.0 1 0 0 1 1 1 0 CDC45-like protein TCP PF03634.8 CDI77346.1 - 0.15 12.3 8.9 0.19 12.1 6.1 1.2 1 0 0 1 1 1 0 TCP family transcription factor Band_3_cyto PF07565.8 CDI77346.1 - 0.19 11.2 7.5 0.23 10.9 5.2 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Herpes_DNAp_acc PF04929.7 CDI77346.1 - 0.25 10.2 7.6 0.27 10.1 5.3 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor FAM60A PF15396.1 CDI77346.1 - 0.26 11.0 6.7 0.32 10.7 4.6 1.2 1 0 0 1 1 1 0 Protein Family FAM60A BAF1_ABF1 PF04684.8 CDI77346.1 - 0.26 10.1 21.6 0.31 9.8 15.0 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor PRCC PF10253.4 CDI77346.1 - 0.3 11.7 19.8 0.37 11.4 13.7 1.1 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting Herpes_TAF50 PF03326.8 CDI77346.1 - 0.33 9.8 17.4 0.37 9.6 12.1 1.1 1 0 0 1 1 1 0 Herpesvirus transcription activation factor (transactivator) Herpes_UL87 PF03043.9 CDI77346.1 - 0.33 9.2 2.5 0.39 9.0 1.7 1.0 1 0 0 1 1 1 0 Herpesvirus UL87 family DUF4603 PF15376.1 CDI77346.1 - 0.35 7.9 11.8 0.43 7.7 8.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) DUF605 PF04652.11 CDI77346.1 - 0.44 9.9 19.0 0.52 9.6 13.2 1.0 1 0 0 1 1 1 0 Vta1 like SR-25 PF10500.4 CDI77346.1 - 0.46 9.9 30.6 1.4 8.3 21.2 1.6 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein PAT1 PF09770.4 CDI77346.1 - 0.48 8.5 21.0 0.51 8.5 14.6 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Spc7_N PF15402.1 CDI77346.1 - 0.66 7.9 15.6 0.8 7.6 10.8 1.0 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 Neur_chan_memb PF02932.11 CDI77346.1 - 0.7 9.7 4.1 0.75 9.6 2.9 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region CDK5_activator PF03261.10 CDI77346.1 - 0.7 9.1 11.5 0.86 8.8 8.0 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein Bul1_N PF04425.7 CDI77346.1 - 0.89 8.0 12.6 1.1 7.7 8.7 1.0 1 0 0 1 1 1 0 Bul1 N terminus Gag_spuma PF03276.9 CDI77346.1 - 1.1 7.5 13.7 1.2 7.3 9.5 1.1 1 0 0 1 1 1 0 Spumavirus gag protein Presenilin PF01080.12 CDI77346.1 - 1.1 7.9 4.7 1.2 7.8 3.3 1.1 1 0 0 1 1 1 0 Presenilin DUF1980 PF09323.5 CDI77346.1 - 1.3 8.7 5.8 1.5 8.5 4.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) THRAP3_BCLAF1 PF15440.1 CDI77346.1 - 1.6 7.3 21.9 2 7.0 15.2 1.0 1 0 0 1 1 1 0 THRAP3/BCLAF1 family UPF0560 PF10577.4 CDI77346.1 - 6.7 4.8 14.7 8.6 4.4 10.2 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 MSA-2c PF12238.3 CDI77346.1 - 8.1 6.0 11.6 10 5.6 8.1 1.2 1 0 0 1 1 1 0 Merozoite surface antigen 2c DUF972 PF06156.8 CDI77396.1 - 1.5e-05 25.3 17.5 0.32 11.3 0.2 7.0 3 3 3 6 6 6 4 Protein of unknown function (DUF972) Herpes_U30 PF04523.8 CDI77396.1 - 0.9 6.9 3.0 14 2.9 0.0 3.0 2 1 0 2 2 2 0 Herpes virus tegument protein U30 APG17 PF04108.7 CDI77396.1 - 3.5 6.3 53.6 0.082 11.6 1.8 5.8 1 1 4 5 5 5 0 Autophagy protein Apg17 GPCR_chapero_1 PF11904.3 CDI77398.1 - 0.0073 15.4 6.7 0.0088 15.2 4.6 1.3 1 0 0 1 1 1 1 GPCR-chaperone Mucin PF01456.12 CDI77398.1 - 0.0096 15.6 10.3 0.0096 15.6 7.1 2.2 2 1 0 2 2 1 1 Mucin-like glycoprotein Med15 PF09606.5 CDI77398.1 - 0.015 13.4 52.2 0.018 13.2 36.2 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Shisa PF13908.1 CDI77398.1 - 0.022 14.9 1.1 0.022 14.9 0.7 3.3 2 1 0 2 2 1 0 Wnt and FGF inhibitory regulator DUF2413 PF10310.4 CDI77398.1 - 0.15 10.8 23.8 0.27 10.0 16.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) DUF1510 PF07423.6 CDI77398.1 - 0.45 9.8 24.1 0.7 9.2 16.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) RR_TM4-6 PF06459.7 CDI77398.1 - 0.82 9.5 16.3 1.5 8.6 11.3 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF4045 PF13254.1 CDI77398.1 - 1.3 8.1 18.2 2.1 7.5 12.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) PAT1 PF09770.4 CDI77398.1 - 2.2 6.4 44.6 2.9 5.9 30.9 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Hid1 PF12722.2 CDI77398.1 - 2.4 5.7 20.3 3 5.4 14.1 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein CDC45 PF02724.9 CDI77398.1 - 3.4 5.6 23.3 4.3 5.2 16.2 1.1 1 0 0 1 1 1 0 CDC45-like protein FAM60A PF15396.1 CDI77398.1 - 6.8 6.3 16.5 12 5.5 11.4 1.4 1 0 0 1 1 1 0 Protein Family FAM60A DUF3595 PF12166.3 CDI77398.1 - 7.7 5.2 11.6 10 4.8 8.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3595) IQ PF00612.22 CDI77410.1 - 0.00059 19.2 0.3 0.0029 17.0 0.0 2.4 2 0 0 2 2 2 1 IQ calmodulin-binding motif OmpH PF03938.9 CDI77410.1 - 0.15 12.0 17.8 1.8 8.4 4.3 2.8 2 1 0 2 2 2 0 Outer membrane protein (OmpH-like) DUF3984 PF13136.1 CDI77411.1 - 0.0035 16.6 21.1 0.0035 16.6 14.6 3.9 5 0 0 5 5 5 1 Protein of unknown function (DUF3984) Suf PF05843.9 CDI77411.1 - 0.035 13.8 10.5 0.058 13.1 3.7 2.5 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) Activator_LAG-3 PF11498.3 CDI77411.1 - 3.9 6.1 45.0 0.32 9.6 13.5 2.4 2 0 0 2 2 2 0 Transcriptional activator LAG-3 DUF3617 PF12276.3 CDI77421.1 - 0.088 12.2 8.1 0.11 11.9 5.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3617) TALPID3 PF15324.1 CDI77421.1 - 0.43 7.8 15.8 0.45 7.8 10.9 1.0 1 0 0 1 1 1 0 Hedgehog signalling target DUF2215 PF10225.4 CDI77421.1 - 0.69 9.3 3.3 0.73 9.2 2.3 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) Shadoo PF14999.1 CDI77421.1 - 1.9 8.3 6.8 2.2 8.1 4.7 1.1 1 0 0 1 1 1 0 Shadow of prion protein, neuroprotective Activator_LAG-3 PF11498.3 CDI77421.1 - 5.7 5.5 31.3 6.1 5.4 21.7 1.0 1 0 0 1 1 1 0 Transcriptional activator LAG-3 HemX PF04375.9 CDI77421.1 - 7.7 4.9 21.6 8.7 4.8 15.0 1.0 1 0 0 1 1 1 0 HemX RNA_pol_Rpc4 PF05132.9 CDI77423.1 - 2.7e-08 33.8 8.4 2.7e-08 33.8 5.8 6.5 5 2 1 6 6 6 1 RNA polymerase III RPC4 SprA-related PF12118.3 CDI77423.1 - 0.0007 19.0 39.4 0.0007 19.0 27.3 5.0 3 1 0 4 4 4 1 SprA-related family DUF755 PF05501.6 CDI77423.1 - 0.0021 18.0 13.7 0.0021 18.0 9.5 7.5 6 2 0 6 6 6 1 Domain of unknown function (DUF755) BLVR PF06375.6 CDI77423.1 - 0.018 14.9 2.4 0.018 14.9 1.7 5.3 5 1 0 5 5 5 0 Bovine leukaemia virus receptor (BLVR) Rubella_E2 PF05749.6 CDI77423.1 - 0.041 13.1 0.1 0.077 12.2 0.0 1.5 1 0 0 1 1 1 0 Rubella membrane glycoprotein E2 Utp14 PF04615.8 CDI77423.1 - 0.8 7.8 65.3 1.4 6.9 13.8 2.4 2 0 0 2 2 2 0 Utp14 protein SoxE PF06525.6 CDI77423.1 - 3.6 6.8 7.9 3.1 7.0 1.9 2.4 2 0 0 2 2 2 0 Sulfocyanin (SoxE) Macoilin PF09726.4 CDI77424.1 - 8e-05 21.1 42.1 0.00014 20.3 29.2 1.3 1 0 0 1 1 1 1 Transmembrane protein Ribosomal_S10 PF00338.17 CDI77424.1 - 0.0011 18.7 6.2 0.0019 17.9 0.0 2.6 2 0 0 2 2 2 1 Ribosomal protein S10p/S20e HemX PF04375.9 CDI77424.1 - 0.0041 15.7 24.5 0.0041 15.7 17.0 2.9 2 1 1 3 3 2 1 HemX PAT1 PF09770.4 CDI77424.1 - 0.16 10.2 70.8 0.0016 16.7 44.0 1.3 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 Asp-B-Hydro_N PF05279.6 CDI77424.1 - 0.38 10.5 15.7 0.64 9.8 10.9 1.3 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region GPCR_chapero_1 PF11904.3 CDI77424.1 - 0.49 9.4 24.2 0.063 12.3 8.9 2.1 2 0 0 2 2 2 0 GPCR-chaperone Hid1 PF12722.2 CDI77424.1 - 2.1 5.9 42.9 0.51 7.9 4.8 2.1 2 0 0 2 2 2 0 High-temperature-induced dauer-formation protein Na_trans_assoc PF06512.8 CDI77424.1 - 2.5 8.0 25.0 1 9.2 0.8 2.4 2 0 0 2 2 2 0 Sodium ion transport-associated Spore_coat_CotO PF14153.1 CDI77424.1 - 3.5 7.0 38.9 0.35 10.2 22.4 2.1 2 0 0 2 2 2 0 Spore coat protein CotO GAGA_bind PF06217.7 CDI77424.1 - 5.1 6.9 27.1 0.94 9.3 13.9 2.1 2 0 0 2 2 2 0 GAGA binding protein-like family Herpes_env PF01673.13 CDI77424.1 - 5.1 5.5 24.8 0.33 9.4 13.0 1.8 2 0 0 2 2 2 0 Herpesvirus putative major envelope glycoprotein Ycf1 PF05758.7 CDI77424.1 - 6.3 4.3 26.4 0.16 9.6 13.5 1.7 2 0 0 2 2 2 0 Ycf1 DUF572 PF04502.8 CDI77424.1 - 6.6 5.8 44.8 0.37 9.9 15.3 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF572) Neur_chan_memb PF02932.11 CDI77424.1 - 7.1 6.4 24.0 1 9.2 10.4 2.2 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region SAPS PF04499.10 CDI77424.1 - 7.5 5.0 29.8 1.2 7.6 13.3 2.1 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein V_ATPase_I PF01496.14 CDI77432.1 - 0.015 13.1 2.9 0.018 12.9 2.0 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4446 PF14584.1 CDI77432.1 - 0.047 13.5 0.6 0.047 13.5 0.4 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF4446) DUF572 PF04502.8 CDI77432.1 - 0.08 12.1 8.5 0.1 11.8 5.9 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF572) APG6 PF04111.7 CDI77432.1 - 0.14 11.1 15.4 0.019 13.9 6.5 1.9 2 0 0 2 2 2 0 Autophagy protein Apg6 DUF3584 PF12128.3 CDI77432.1 - 0.63 7.3 17.6 0.6 7.3 10.5 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) DUF972 PF06156.8 CDI77432.1 - 0.68 10.3 3.4 1.6 9.1 2.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF972) Frankia_peptide PF14407.1 CDI77432.1 - 1.1 9.0 10.2 0.077 12.7 0.8 3.0 2 1 1 3 3 3 0 Ribosomally synthesized peptide prototyped by Frankia Franean1_4349. Spc7 PF08317.6 CDI77432.1 - 3.1 6.3 10.2 0.22 10.1 3.8 1.4 2 0 0 2 2 2 0 Spc7 kinetochore protein AAA_23 PF13476.1 CDI77432.1 - 3.3 7.9 5.8 4.6 7.5 4.0 1.1 1 0 0 1 1 1 0 AAA domain Phage_GP20 PF06810.6 CDI77432.1 - 6.8 6.1 13.5 0.081 12.3 3.8 1.9 2 0 0 2 2 2 0 Phage minor structural protein GP20 DUF2360 PF10152.4 CDI77432.1 - 7 6.9 9.4 8.8 6.6 6.0 1.6 1 1 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) Seryl_tRNA_N PF02403.17 CDI77432.1 - 9.9 6.2 16.6 0.75 9.8 6.6 2.1 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Suf PF05843.9 CDI77441.1 - 0.0008 19.2 19.3 0.0058 16.4 2.3 2.3 2 0 0 2 2 2 2 Suppressor of forked protein (Suf) FimP PF09766.4 CDI77441.1 - 0.00097 18.2 23.3 0.0016 17.5 6.1 2.2 2 0 0 2 2 2 2 Fms-interacting protein Spt20 PF12090.3 CDI77441.1 - 0.0039 16.5 1.7 0.0039 16.5 1.2 2.5 2 1 0 2 2 1 1 Spt20 family DUF4448 PF14610.1 CDI77441.1 - 0.0068 15.9 4.9 0.014 14.8 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF4448) PH_4 PF15404.1 CDI77441.1 - 0.031 13.7 12.0 0.26 10.7 0.7 2.4 2 0 0 2 2 2 0 Pleckstrin homology domain PBP1_TM PF14812.1 CDI77441.1 - 0.11 12.8 6.5 0.16 12.3 1.3 2.5 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF106 PF01956.11 CDI77441.1 - 0.22 11.0 12.7 0.017 14.6 3.1 2.2 2 0 0 2 2 2 0 Integral membrane protein DUF106 CLN3 PF02487.12 CDI77441.1 - 1.2 7.8 8.2 0.021 13.6 0.7 1.7 2 0 0 2 2 2 0 CLN3 protein Cwf_Cwc_15 PF04889.7 CDI77441.1 - 1.4 8.5 24.8 3 7.4 5.2 2.3 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein CDC45 PF02724.9 CDI77441.1 - 1.4 6.8 20.8 1.4 6.8 6.6 2.3 2 0 0 2 2 2 0 CDC45-like protein Sec62 PF03839.11 CDI77441.1 - 1.8 7.9 14.3 0.16 11.4 3.4 2.1 2 0 0 2 2 2 0 Translocation protein Sec62 TMEM223 PF14640.1 CDI77441.1 - 4.8 7.0 6.9 11 5.9 0.2 2.3 2 0 0 2 2 2 0 Transmembrane protein 223 DUF3801 PF12687.2 CDI77441.1 - 5.1 6.6 26.6 0.15 11.6 1.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3801) Herpes_BLLF1 PF05109.8 CDI77441.1 - 8.3 4.2 30.3 10 3.9 21.0 1.1 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) Mem_trans PF03547.13 CDI77445.1 - 9 4.4 13.2 1.2 7.3 0.1 2.8 2 0 0 2 2 2 0 Membrane transport protein PIG-U PF06728.8 CDI77456.1 - 0.7 8.6 0.5 2.4 6.9 0.3 1.9 1 0 0 1 1 1 0 GPI transamidase subunit PIG-U Sporozoite_P67 PF05642.6 CDI77457.1 - 9.2e-05 20.5 2.2 9.2e-05 20.5 1.5 12.4 11 2 0 12 12 12 4 Sporozoite P67 surface antigen Med15 PF09606.5 CDI77457.1 - 0.00018 19.8 19.7 0.00018 19.8 13.6 17.1 11 6 3 14 14 14 2 ARC105 or Med15 subunit of Mediator complex non-fungal SR-25 PF10500.4 CDI77457.1 - 0.0019 17.7 15.4 0.0019 17.7 10.7 28.4 26 8 6 32 32 32 1 Nuclear RNA-splicing-associated protein SprA-related PF12118.3 CDI77508.1 - 0.00034 20.0 40.5 0.00045 19.6 28.1 1.1 1 0 0 1 1 1 1 SprA-related family DUF4366 PF14283.1 CDI77508.1 - 0.00051 19.5 5.8 0.00061 19.2 4.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4366) Plasmodium_Vir PF05795.6 CDI77508.1 - 0.022 13.9 5.8 0.023 13.9 4.0 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Isy1 PF06246.7 CDI77508.1 - 0.025 13.9 19.9 0.03 13.7 13.8 1.1 1 0 0 1 1 1 0 Isy1-like splicing family Dsh_C PF12316.3 CDI77508.1 - 0.029 14.4 7.5 0.038 14.1 5.2 1.2 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal LMBR1 PF04791.11 CDI77508.1 - 0.13 10.8 9.4 0.15 10.5 6.5 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Raftlin PF15250.1 CDI77508.1 - 0.22 10.0 18.2 0.26 9.7 12.6 1.1 1 0 0 1 1 1 0 Raftlin DUF897 PF05982.7 CDI77508.1 - 0.26 10.0 1.5 0.25 10.1 1.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF897) ABC2_membrane_3 PF12698.2 CDI77508.1 - 0.35 9.8 5.4 0.37 9.7 3.7 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein HCO3_cotransp PF00955.16 CDI77508.1 - 0.36 9.4 4.4 0.41 9.2 3.1 1.1 1 0 0 1 1 1 0 HCO3- transporter family DUF1088 PF06469.6 CDI77508.1 - 0.39 10.1 11.4 0.68 9.3 7.9 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1088) S_layer_C PF05124.7 CDI77508.1 - 0.51 9.9 3.8 0.66 9.5 2.6 1.1 1 0 0 1 1 1 0 S-layer like family, C-terminal region Cas1_AcylT PF07779.7 CDI77508.1 - 0.56 8.6 4.1 0.77 8.1 2.8 1.3 1 0 0 1 1 1 0 10 TM Acyl Transferase domain found in Cas1p eIF-3_zeta PF05091.7 CDI77508.1 - 0.57 8.7 23.1 0.69 8.4 16.0 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) YjgP_YjgQ PF03739.9 CDI77508.1 - 0.65 8.6 8.2 0.75 8.4 5.7 1.2 1 0 0 1 1 1 0 Predicted permease YjgP/YjgQ family Nucleoside_tran PF01733.13 CDI77508.1 - 0.79 8.8 8.7 1.1 8.3 6.0 1.2 1 0 0 1 1 1 0 Nucleoside transporter Peptidase_M56 PF05569.6 CDI77508.1 - 1.4 7.7 7.3 1.8 7.4 5.1 1.1 1 0 0 1 1 1 0 BlaR1 peptidase M56 Kei1 PF08552.6 CDI77508.1 - 3.1 7.4 16.4 5.1 6.7 11.3 1.6 1 1 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 DUF3708 PF12501.3 CDI77508.1 - 3.9 7.2 7.1 5.3 6.8 4.9 1.3 1 0 0 1 1 1 0 Phosphate ATP-binding cassette transporter Gti1_Pac2 PF09729.4 CDI77508.1 - 4.4 7.1 19.9 0.3 10.9 9.5 1.8 1 1 1 2 2 2 0 Gti1/Pac2 family Cellulose_synt PF03552.9 CDI77508.1 - 4.6 5.4 7.1 4.4 5.4 4.9 1.1 1 0 0 1 1 1 0 Cellulose synthase DUF4526 PF15029.1 CDI77508.1 - 5 6.6 8.0 7.1 6.1 5.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4526) Corona_nucleoca PF00937.13 CDI77508.1 - 5 5.9 29.2 0.22 10.4 16.2 1.6 2 0 0 2 2 2 0 Coronavirus nucleocapsid protein Anoctamin PF04547.7 CDI77508.1 - 5.8 5.4 13.3 7.8 5.0 9.2 1.3 1 0 0 1 1 1 0 Calcium-activated chloride channel RR_TM4-6 PF06459.7 CDI77508.1 - 5.9 6.7 17.1 0.053 13.4 6.5 1.5 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 PBP1_TM PF14812.1 CDI77508.1 - 6 7.2 20.7 0.041 14.1 5.0 2.5 2 1 1 3 3 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF3446 PF11928.3 CDI77510.1 - 0.022 14.9 15.9 0.022 14.9 11.0 3.6 2 1 0 2 2 2 0 Domain of unknown function (DUF3446) SR-25 PF10500.4 CDI77510.1 - 0.046 13.1 58.8 0.18 11.2 17.4 2.2 1 1 0 2 2 2 0 Nuclear RNA-splicing-associated protein DUF4367 PF14285.1 CDI77510.1 - 0.1 11.9 1.0 0.14 11.4 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4367) Cwf_Cwc_15 PF04889.7 CDI77510.1 - 0.2 11.3 25.4 0.42 10.2 1.7 2.1 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein DUF4179 PF13786.1 CDI77510.1 - 0.4 10.9 3.7 0.63 10.3 1.4 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4179) AAA_23 PF13476.1 CDI77510.1 - 0.79 10.0 22.9 0.36 11.1 8.5 2.1 2 0 0 2 2 2 0 AAA domain RskA PF10099.4 CDI77510.1 - 6.9 6.3 32.3 0.28 10.9 17.1 2.3 2 1 0 2 2 2 0 Anti-sigma-K factor rskA MLANA PF14991.1 CDI77510.1 - 9.6 6.2 9.6 0.16 12.0 0.3 2.2 2 1 0 2 2 2 0 Protein melan-A Shadoo PF14999.1 CDI77522.1 - 4 7.3 15.0 0.072 12.9 3.6 2.2 2 0 0 2 2 2 0 Shadow of prion protein, neuroprotective DUF390 PF04094.9 CDI77529.1 - 0.046 11.7 11.8 0.054 11.5 8.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF390) SpaB_C PF14028.1 CDI77529.1 - 0.19 11.2 7.1 0.23 10.9 4.9 1.2 1 0 0 1 1 1 0 SpaB C-terminal domain Med15 PF09606.5 CDI77529.1 - 0.38 8.9 18.0 0.44 8.6 12.5 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF3708 PF12501.3 CDI77529.1 - 0.51 10.1 10.8 0.97 9.2 7.5 1.4 1 1 0 1 1 1 0 Phosphate ATP-binding cassette transporter Exonuc_VII_L PF02601.10 CDI77529.1 - 0.97 8.5 13.6 1.1 8.3 9.4 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit Band_3_cyto PF07565.8 CDI77529.1 - 1.3 8.4 9.1 1.5 8.2 6.3 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain DUF2413 PF10310.4 CDI77529.1 - 3.5 6.3 15.5 4.2 6.0 10.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) DDHD PF02862.12 CDI77529.1 - 3.6 7.3 8.1 4.5 6.9 5.6 1.2 1 0 0 1 1 1 0 DDHD domain RR_TM4-6 PF06459.7 CDI77529.1 - 9.3 6.0 13.7 14 5.5 9.5 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Neur_chan_memb PF02932.11 CDI77529.1 - 9.8 5.9 10.1 14 5.4 7.0 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region EGF_CA PF07645.10 CDI77531.1 - 4.2e-57 189.8 79.9 1.1e-11 44.5 5.2 6.1 6 0 0 6 6 6 6 Calcium-binding EGF domain EGF_3 PF12947.2 CDI77531.1 - 4.4e-44 148.1 85.4 2.8e-09 36.7 7.0 6.3 6 0 0 6 6 6 6 EGF domain cEGF PF12662.2 CDI77531.1 - 9.1e-29 98.7 53.9 1.7e-07 30.7 3.0 6.2 6 0 0 6 6 6 5 Complement Clr-like EGF-like EGF PF00008.22 CDI77531.1 - 2.7e-25 87.9 71.1 3.6e-06 26.8 6.1 6.5 6 0 0 6 6 6 6 EGF-like domain EGF_MSP1_1 PF12946.2 CDI77531.1 - 2.1e-11 43.4 54.7 0.0037 17.0 3.5 6.2 6 0 0 6 6 6 5 MSP1 EGF domain 1 FXa_inhibition PF14670.1 CDI77531.1 - 3.6e-10 39.7 80.3 0.00073 19.6 3.3 6.5 6 1 0 6 6 6 5 Coagulation Factor Xa inhibitory site hEGF PF12661.2 CDI77531.1 - 6.3e-09 35.3 26.6 0.018 15.0 0.3 6.2 5 0 0 5 5 5 4 Human growth factor-like EGF EGF_2 PF07974.8 CDI77531.1 - 1.7e-07 31.2 67.1 0.00012 22.1 2.3 6.5 6 0 0 6 6 6 4 EGF-like domain Ycf1 PF05758.7 CDI77541.1 - 0.00045 18.1 0.3 0.00045 18.1 0.2 1.0 1 0 0 1 1 1 1 Ycf1 DUF4557 PF15101.1 CDI77541.1 - 0.00072 19.4 5.4 0.00072 19.4 3.8 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4557) V_ATPase_I PF01496.14 CDI77541.1 - 0.12 10.2 6.6 0.16 9.8 4.6 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF342 PF03961.8 CDI77541.1 - 0.51 8.6 9.1 0.67 8.2 6.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF4175 PF13779.1 CDI77541.1 - 5.4 4.5 35.3 9.9 3.7 24.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Cpn60_TCP1 PF00118.19 CDI77543.1 - 3e-117 392.2 1.4 3.6e-117 391.9 1.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family TB2_DP1_HVA22 PF03134.14 CDI77544.1 - 5.1e-19 67.7 3.3 7.3e-19 67.3 2.3 1.2 1 0 0 1 1 1 1 TB2/DP1, HVA22 family Aa_trans PF01490.13 CDI77544.1 - 0.08 11.4 0.7 0.13 10.7 0.5 1.3 1 0 0 1 1 1 0 Transmembrane amino acid transporter protein SURF1 PF02104.10 CDI77545.1 - 1.1e-28 100.4 0.5 5.5e-25 88.4 0.4 3.2 1 1 0 1 1 1 1 SURF1 family ATP-synt_ab PF00006.20 CDI77545.1 - 0.031 13.7 0.0 0.056 12.9 0.0 1.3 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain DUF4367 PF14285.1 CDI77552.1 - 0.067 12.4 0.1 0.067 12.4 0.1 8.1 9 3 0 9 9 9 0 Domain of unknown function (DUF4367) OPT PF03169.10 CDI77556.1 - 0.2 10.0 0.4 2.1 6.6 0.0 2.3 2 1 0 2 2 2 0 OPT oligopeptide transporter protein SF-assemblin PF06705.6 CDI77558.1 - 0.011 14.9 7.0 0.014 14.5 4.8 1.2 1 0 0 1 1 1 0 SF-assemblin/beta giardin UPF0278 PF08745.6 CDI77558.1 - 0.03 13.5 0.4 0.047 12.9 0.3 1.3 1 0 0 1 1 1 0 UPF0278 family Alpha-2-MRAP_C PF06401.6 CDI77558.1 - 0.031 14.1 2.7 0.039 13.7 1.9 1.1 1 0 0 1 1 1 0 Alpha-2-macroglobulin RAP, C-terminal domain DUF1741 PF08427.5 CDI77558.1 - 0.16 11.3 1.9 0.2 11.1 1.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1741) CDC37_N PF03234.9 CDI77558.1 - 0.2 11.9 4.4 0.28 11.4 3.0 1.3 1 1 0 1 1 1 0 Cdc37 N terminal kinase binding DUF445 PF04286.7 CDI77558.1 - 0.93 8.9 5.5 1 8.8 3.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF445) HrpA_pilin PF09589.5 CDI77558.1 - 1.4 9.3 3.9 2.4 8.6 2.7 1.6 1 1 0 1 1 1 0 HrpA pilus formation protein ATP-synt_B PF00430.13 CDI77558.1 - 1.8 8.3 10.0 3.3 7.5 7.0 1.5 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) DUF4363 PF14276.1 CDI77558.1 - 2 8.1 4.6 2.6 7.7 0.9 2.4 1 1 2 3 3 3 0 Domain of unknown function (DUF4363) DUF2458 PF10454.4 CDI77558.1 - 4.2 7.2 7.5 5.1 6.9 2.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2458) YtxH PF12732.2 CDI77558.1 - 5.1 7.5 8.1 1.5e+02 2.8 5.6 2.4 1 1 0 1 1 1 0 YtxH-like protein CAF-1_p150 PF11600.3 CDI77566.1 - 0.0034 16.7 26.3 0.0038 16.6 18.2 1.2 1 0 0 1 1 1 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal Med15 PF09606.5 CDI77566.1 - 0.022 12.9 27.5 0.022 12.9 19.1 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Nop53 PF07767.6 CDI77566.1 - 0.023 13.7 18.9 0.026 13.5 13.1 1.0 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) SprA-related PF12118.3 CDI77566.1 - 0.12 11.7 37.6 0.13 11.5 26.1 1.1 1 0 0 1 1 1 0 SprA-related family CDK5_activator PF03261.10 CDI77566.1 - 0.13 11.5 23.7 0.13 11.6 16.4 1.0 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein THRAP3_BCLAF1 PF15440.1 CDI77566.1 - 0.23 10.1 37.8 0.31 9.6 26.2 1.2 1 0 0 1 1 1 0 THRAP3/BCLAF1 family Suf PF05843.9 CDI77566.1 - 0.33 10.6 27.0 0.39 10.4 18.7 1.0 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) PGA2 PF07543.7 CDI77566.1 - 0.37 10.5 8.3 0.44 10.3 5.7 1.2 1 0 0 1 1 1 0 Protein trafficking PGA2 RR_TM4-6 PF06459.7 CDI77566.1 - 0.37 10.6 14.9 0.38 10.5 10.3 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 AAA_23 PF13476.1 CDI77566.1 - 0.64 10.3 13.4 0.71 10.1 9.3 1.1 1 0 0 1 1 1 0 AAA domain CDC45 PF02724.9 CDI77566.1 - 0.93 7.4 22.3 1 7.3 15.4 1.0 1 0 0 1 1 1 0 CDC45-like protein DUF737 PF05300.6 CDI77566.1 - 1.5 8.7 22.9 2 8.3 15.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF737) DUF3801 PF12687.2 CDI77566.1 - 1.6 8.2 18.3 2.2 7.8 12.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3801) Spore_coat_CotO PF14153.1 CDI77566.1 - 1.6 8.0 22.7 2 7.8 15.7 1.1 1 0 0 1 1 1 0 Spore coat protein CotO SAGA-Tad1 PF12767.2 CDI77566.1 - 1.7 8.2 23.9 1.9 8.0 16.5 1.1 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit NARP1 PF12569.3 CDI77566.1 - 1.7 7.2 15.5 1.9 7.1 10.7 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 NPR3 PF03666.8 CDI77566.1 - 1.8 7.0 23.6 2.1 6.7 16.4 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF4175 PF13779.1 CDI77566.1 - 2.1 5.9 29.7 2.1 5.9 20.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) PAT1 PF09770.4 CDI77566.1 - 2.2 6.4 29.3 2.4 6.3 20.3 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF1510 PF07423.6 CDI77566.1 - 2.3 7.5 19.7 2.6 7.3 13.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) SR-25 PF10500.4 CDI77566.1 - 2.3 7.6 49.6 19 4.6 34.4 1.9 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein Corona_nucleoca PF00937.13 CDI77566.1 - 2.7 6.8 33.1 3.5 6.4 23.0 1.1 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein DDHD PF02862.12 CDI77566.1 - 2.7 7.7 22.4 3.2 7.5 15.6 1.2 1 0 0 1 1 1 0 DDHD domain Zip PF02535.17 CDI77566.1 - 3 6.7 14.4 3.2 6.6 10.0 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter FLO_LFY PF01698.11 CDI77566.1 - 3.1 6.5 19.3 3.3 6.4 13.4 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein Rtf2 PF04641.7 CDI77566.1 - 3.3 6.8 18.9 3.8 6.6 13.1 1.2 1 0 0 1 1 1 0 Rtf2 RING-finger Prog_receptor PF02161.10 CDI77566.1 - 3.5 6.3 15.8 3.8 6.2 10.9 1.0 1 0 0 1 1 1 0 Progesterone receptor VID27 PF08553.5 CDI77566.1 - 4.1 5.4 16.1 4.3 5.4 11.1 1.0 1 0 0 1 1 1 0 VID27 cytoplasmic protein DUF2201_N PF13203.1 CDI77566.1 - 5.6 6.0 20.8 6.4 5.8 14.4 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain DUF4407 PF14362.1 CDI77566.1 - 5.9 5.7 10.4 6.2 5.6 7.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Macoilin PF09726.4 CDI77566.1 - 6.1 5.0 27.6 7.9 4.6 19.2 1.2 1 0 0 1 1 1 0 Transmembrane protein AUX_IAA PF02309.11 CDI77566.1 - 6.2 6.5 18.0 7.9 6.1 12.5 1.3 1 0 0 1 1 1 0 AUX/IAA family Spc7_N PF15402.1 CDI77566.1 - 6.4 4.6 26.5 7.6 4.3 18.4 1.2 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 MRP-S31 PF15433.1 CDI77566.1 - 6.7 6.0 20.9 7.9 5.8 14.5 1.2 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 DUF2413 PF10310.4 CDI77566.1 - 6.8 5.3 23.7 7.2 5.3 16.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) Serinc PF03348.10 CDI77566.1 - 7.2 5.1 15.1 8 5.0 10.5 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) DUF572 PF04502.8 CDI77566.1 - 7.3 5.7 26.2 7.6 5.6 18.2 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF605 PF04652.11 CDI77566.1 - 7.7 5.7 34.2 9.4 5.5 23.7 1.0 1 0 0 1 1 1 0 Vta1 like Raftlin PF15250.1 CDI77566.1 - 9.1 4.6 22.0 11 4.4 15.2 1.1 1 0 0 1 1 1 0 Raftlin PBP_sp32 PF07222.7 CDI77566.1 - 9.3 5.3 21.2 11 5.1 14.7 1.1 1 0 0 1 1 1 0 Proacrosin binding protein sp32 DUF601 PF04642.7 CDI77566.1 - 9.7 5.4 18.6 10 5.3 12.9 1.1 1 0 0 1 1 1 0 Protein of unknown function, DUF601 Sec62 PF03839.11 CDI77566.1 - 9.7 5.5 15.7 11 5.2 10.9 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 Hep_59 PF07052.6 CDI77567.1 - 6.5e-20 71.4 2.8 6.5e-20 71.4 1.9 1.7 2 0 0 2 2 2 1 Hepatocellular carcinoma-associated antigen 59 Eaf7 PF07904.8 CDI77567.1 - 0.32 10.9 4.1 0.36 10.8 1.4 2.1 3 0 0 3 3 3 0 Chromatin modification-related protein EAF7 CDP-OH_P_transf PF01066.16 CDI77576.1 - 1.3e-16 60.7 1.4 1.3e-16 60.7 1.0 3.8 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase DUF3467 PF11950.3 CDI77585.1 - 0.77 9.8 0.0 0.77 9.8 0.0 3.8 3 2 0 3 3 3 0 Protein of unknown function (DUF3467) ELMO_CED12 PF04727.8 CDI77596.1 - 5.4e-10 39.0 0.0 1.5e-09 37.6 0.0 1.7 1 1 1 2 2 2 1 ELMO/CED-12 family His_Phos_2 PF00328.17 CDI77597.1 - 8.8e-13 48.2 18.8 2.6e-05 23.7 0.0 4.4 4 1 0 4 4 4 3 Histidine phosphatase superfamily (branch 2) Spt20 PF12090.3 CDI77597.1 - 0.06 12.7 6.1 0.17 11.1 0.5 2.7 2 0 0 2 2 2 0 Spt20 family AAA_23 PF13476.1 CDI77597.1 - 5.3 7.3 9.9 1.3 9.3 0.3 2.6 3 0 0 3 3 3 0 AAA domain DUF4094 PF13334.1 CDI77597.1 - 7.2 7.0 10.7 2.6 8.5 0.4 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4094) SOG2 PF10428.4 CDI77611.1 - 0.094 11.3 6.1 0.1 11.2 4.2 1.0 1 0 0 1 1 1 0 RAM signalling pathway protein DUF2464 PF10240.4 CDI77611.1 - 0.16 11.2 1.2 0.18 11.1 0.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2464) Apc15p PF05841.6 CDI77611.1 - 0.17 12.6 6.0 0.2 12.4 4.2 1.1 1 0 0 1 1 1 0 Apc15p protein SRP-alpha_N PF04086.8 CDI77611.1 - 0.18 11.1 1.7 0.22 10.8 1.2 1.0 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal DUF1180 PF06679.7 CDI77611.1 - 0.3 10.9 6.7 0.34 10.7 4.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) PAP1 PF08601.5 CDI77611.1 - 0.73 9.4 4.9 0.81 9.3 3.4 1.0 1 0 0 1 1 1 0 Transcription factor PAP1 DUF2360 PF10152.4 CDI77611.1 - 1.2 9.4 8.6 1.4 9.1 6.0 1.2 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) DLIC PF05783.6 CDI77611.1 - 1.6 7.2 4.6 1.8 7.1 3.2 1.0 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) Herpes_capsid PF06112.6 CDI77611.1 - 2.6 8.0 12.2 3 7.8 8.4 1.1 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein TFIIA PF03153.8 CDI77611.1 - 2.8 7.7 8.4 3.2 7.5 5.8 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Med3 PF11593.3 CDI77611.1 - 5.5 6.1 15.5 7.2 5.7 10.7 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DUF3138 PF11336.3 CDI77611.1 - 9.7 4.2 14.4 12 3.9 10.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) rve PF00665.21 CDI77620.1 - 2.3e-18 66.4 0.0 6.1e-18 65.0 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 CDI77620.1 - 5.8e-15 55.2 0.0 1.1e-14 54.3 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.19 CDI77620.1 - 1.2e-12 47.2 0.1 2.3e-12 46.3 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain gag-asp_proteas PF13975.1 CDI77620.1 - 4.1e-08 32.9 0.0 1e-07 31.6 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 CDI77620.1 - 7.3e-08 32.8 0.0 1.7e-07 31.6 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.15 CDI77620.1 - 2.2e-06 27.5 0.0 4.6e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease RVP_2 PF08284.6 CDI77620.1 - 1.1e-05 25.3 0.0 2.2e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.5 CDI77620.1 - 0.0024 17.4 0.0 0.005 16.4 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease DUF1758 PF05585.7 CDI77620.1 - 0.2 11.1 0.0 0.43 10.1 0.0 1.4 1 0 0 1 1 1 0 Putative peptidase (DUF1758) SRP54_N PF02881.14 CDI77633.1 - 1.4e-08 34.6 0.3 7.9e-08 32.2 0.1 2.0 2 0 0 2 2 2 1 SRP54-type protein, helical bundle domain PAT1 PF09770.4 CDI77633.1 - 0.00013 20.4 41.4 0.00013 20.4 28.7 2.0 2 0 0 2 2 2 1 Topoisomerase II-associated protein PAT1 SPX PF03105.14 CDI77633.1 - 0.00032 20.5 18.0 0.025 14.3 8.1 2.1 2 0 0 2 2 2 2 SPX domain Spore_coat_CotO PF14153.1 CDI77633.1 - 0.001 18.5 21.0 0.001 18.5 14.5 2.2 2 0 0 2 2 2 1 Spore coat protein CotO Utp14 PF04615.8 CDI77633.1 - 0.0034 15.6 25.6 0.012 13.8 12.9 2.0 2 0 0 2 2 2 2 Utp14 protein Band_3_cyto PF07565.8 CDI77633.1 - 0.021 14.3 26.5 0.64 9.4 0.4 2.2 2 0 0 2 2 2 0 Band 3 cytoplasmic domain Hid1 PF12722.2 CDI77633.1 - 0.028 12.1 24.5 0.038 11.6 11.4 2.0 2 0 0 2 2 2 0 High-temperature-induced dauer-formation protein FAM176 PF14851.1 CDI77633.1 - 0.086 12.5 17.5 0.53 9.9 0.4 2.4 2 0 0 2 2 2 0 FAM176 family Anoctamin PF04547.7 CDI77633.1 - 0.17 10.5 14.4 0.064 11.8 8.2 1.6 1 1 1 2 2 2 0 Calcium-activated chloride channel POP1 PF06978.6 CDI77633.1 - 0.19 11.3 17.6 0.13 11.8 8.1 2.2 2 0 0 2 2 2 0 Ribonucleases P/MRP protein subunit POP1 FAM60A PF15396.1 CDI77633.1 - 0.28 10.8 25.7 1.6 8.3 0.8 2.3 2 0 0 2 2 2 0 Protein Family FAM60A Gti1_Pac2 PF09729.4 CDI77633.1 - 0.61 9.9 21.7 0.097 12.5 6.6 2.6 3 0 0 3 3 3 0 Gti1/Pac2 family SoxE PF06525.6 CDI77633.1 - 0.76 9.0 10.5 0.59 9.3 0.7 2.3 2 0 0 2 2 2 0 Sulfocyanin (SoxE) DUF4045 PF13254.1 CDI77633.1 - 1.4 8.1 29.5 0.19 10.9 12.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4045) PLRV_ORF5 PF01690.12 CDI77633.1 - 1.7 7.6 27.9 2.5 7.1 19.3 1.2 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Nucleoside_tran PF01733.13 CDI77633.1 - 1.8 7.6 12.8 3.4 6.7 5.2 2.2 2 0 0 2 2 2 0 Nucleoside transporter SR-25 PF10500.4 CDI77633.1 - 2 7.8 46.6 0.037 13.5 10.7 2.3 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein SRP-alpha_N PF04086.8 CDI77633.1 - 2.7 7.2 28.1 0.62 9.4 11.5 2.2 2 0 0 2 2 2 0 Signal recognition particle, alpha subunit, N-terminal Cwf_Cwc_15 PF04889.7 CDI77633.1 - 3.4 7.3 29.8 2.7 7.6 0.1 2.2 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Ndc1_Nup PF09531.5 CDI77633.1 - 4.4 5.5 32.7 1.2 7.4 2.2 2.0 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup Draxin PF15550.1 CDI77633.1 - 5.6 6.5 22.1 0.95 9.0 11.1 2.0 2 0 0 2 2 2 0 Draxin YjgP_YjgQ PF03739.9 CDI77633.1 - 6 5.4 12.8 0.14 10.9 4.2 1.7 2 0 0 2 2 2 0 Predicted permease YjgP/YjgQ family PCYCGC PF13798.1 CDI77633.1 - 8.4 6.0 19.2 0.79 9.3 8.2 2.2 2 0 0 2 2 2 0 Protein of unknown function with PCYCGC motif DUF1510 PF07423.6 CDI77634.1 - 0.016 14.5 10.6 0.016 14.5 7.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DUF2946 PF11162.3 CDI77634.1 - 0.02 15.1 8.8 0.023 14.8 6.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2946) FAM176 PF14851.1 CDI77634.1 - 0.037 13.7 5.9 0.044 13.4 4.1 1.2 1 0 0 1 1 1 0 FAM176 family Conotoxin PF02950.12 CDI77634.1 - 0.049 14.4 5.6 0.049 14.4 3.9 2.0 1 1 1 2 2 2 0 Conotoxin DUF4512 PF14975.1 CDI77634.1 - 0.081 13.7 7.2 0.085 13.6 5.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4512) RIC3 PF15361.1 CDI77634.1 - 0.25 11.5 10.7 0.26 11.5 7.4 1.1 1 0 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 7TM_GPCR_Srw PF10324.4 CDI77634.1 - 0.31 10.0 1.6 0.37 9.8 1.1 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srw Protocadherin PF08374.6 CDI77634.1 - 0.33 10.5 9.0 0.34 10.5 6.2 1.0 1 0 0 1 1 1 0 Protocadherin Pap_E4 PF02711.9 CDI77634.1 - 0.45 11.3 16.9 0.51 11.1 11.7 1.1 1 0 0 1 1 1 0 E4 protein DUF4446 PF14584.1 CDI77634.1 - 0.46 10.3 10.6 0.49 10.2 7.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) DUF2370 PF10176.4 CDI77634.1 - 0.56 9.4 8.1 0.6 9.4 5.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) SHR3_chaperone PF08229.6 CDI77634.1 - 0.66 8.8 16.9 0.79 8.6 11.7 1.2 1 0 0 1 1 1 0 ER membrane protein SH3 NicO PF03824.11 CDI77634.1 - 0.82 8.9 4.7 0.86 8.8 3.3 1.0 1 0 0 1 1 1 0 High-affinity nickel-transport protein Serinc PF03348.10 CDI77634.1 - 0.95 8.1 11.6 0.96 8.0 8.0 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) DUF2782 PF11191.3 CDI77634.1 - 1.1 9.2 6.5 2 8.4 4.5 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2782) SID-1_RNA_chan PF13965.1 CDI77634.1 - 1.1 7.2 7.1 1.2 7.2 4.9 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Folate_carrier PF01770.13 CDI77634.1 - 1.2 7.6 10.6 1.1 7.6 7.4 1.0 1 0 0 1 1 1 0 Reduced folate carrier DUF3530 PF12048.3 CDI77634.1 - 1.2 8.0 16.4 1.6 7.6 11.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) Ctr PF04145.10 CDI77634.1 - 1.5 8.8 7.1 1.8 8.6 4.9 1.2 1 0 0 1 1 1 0 Ctr copper transporter family Mem_trans PF03547.13 CDI77634.1 - 1.6 6.9 6.7 1.6 6.9 4.7 1.0 1 0 0 1 1 1 0 Membrane transport protein DUF2149 PF09919.4 CDI77634.1 - 1.7 8.7 7.3 2.1 8.4 5.1 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2149) OAD_gamma PF04277.8 CDI77634.1 - 2 8.8 4.6 8.4 6.8 3.2 1.8 1 1 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain Neur_chan_memb PF02932.11 CDI77634.1 - 2.4 7.9 11.2 2.5 7.9 7.7 1.0 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Endonuc_Holl PF10107.4 CDI77634.1 - 2.5 7.7 16.5 2.6 7.7 11.5 1.0 1 0 0 1 1 1 0 Endonuclease related to archaeal Holliday junction resolvase Zip PF02535.17 CDI77634.1 - 2.7 6.9 11.1 3 6.7 7.7 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Herpes_glycop PF01528.11 CDI77634.1 - 2.9 6.4 7.2 2.9 6.4 5.0 1.0 1 0 0 1 1 1 0 Herpesvirus glycoprotein M DUF3260 PF11658.3 CDI77634.1 - 3.2 5.7 12.2 3.3 5.7 8.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3260) OATP PF03137.15 CDI77634.1 - 3.5 5.5 12.2 3.7 5.4 8.4 1.0 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Peroxin-13_N PF04088.8 CDI77634.1 - 4.1 7.3 8.1 4.9 7.0 5.6 1.3 1 0 0 1 1 1 0 Peroxin 13, N-terminal region Cyto_heme_lyase PF01265.12 CDI77634.1 - 5 6.6 17.0 5.2 6.5 11.8 1.0 1 0 0 1 1 1 0 Cytochrome c/c1 heme lyase Ycf1 PF05758.7 CDI77634.1 - 5.9 4.4 14.8 5.6 4.5 10.3 1.0 1 0 0 1 1 1 0 Ycf1 Otopetrin PF03189.8 CDI77634.1 - 6.7 5.5 10.3 6.9 5.5 7.1 1.0 1 0 0 1 1 1 0 Otopetrin Kei1 PF08552.6 CDI77634.1 - 7.3 6.2 8.9 7.9 6.0 6.2 1.2 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 DUF3357 PF11837.3 CDI77634.1 - 7.5 6.4 10.3 3.2e+02 1.2 7.1 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF3357) Rtf2 PF04641.7 CDI77634.1 - 8.3 5.5 18.1 8.9 5.4 12.6 1.0 1 0 0 1 1 1 0 Rtf2 RING-finger FA_desaturase PF00487.19 CDI77636.1 - 0.037 13.4 0.1 0.084 12.2 0.1 1.6 1 0 0 1 1 1 0 Fatty acid desaturase DivIC PF04977.10 CDI77636.1 - 1.1 8.7 20.5 0.08 12.4 3.6 2.9 3 0 0 3 3 3 0 Septum formation initiator PAT1 PF09770.4 CDI77638.1 - 0.0094 14.2 119.6 0.012 13.9 82.9 1.0 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 V_ATPase_I PF01496.14 CDI77643.1 - 2.6e-13 48.7 0.0 2.6e-13 48.7 0.0 2.1 2 0 0 2 2 2 1 V-type ATPase 116kDa subunit family PLA2_B PF01735.13 CDI77643.1 - 0.012 13.8 0.7 0.021 13.0 0.5 1.3 1 0 0 1 1 1 0 Lysophospholipase catalytic domain Tsg PF04668.7 CDI77643.1 - 1.1 9.4 0.0 1.1 9.4 0.0 2.8 3 0 0 3 3 3 0 Twisted gastrulation (Tsg) protein conserved region FimP PF09766.4 CDI77643.1 - 1.2 8.1 23.3 0.043 12.8 8.3 2.8 3 0 0 3 3 3 0 Fms-interacting protein MRP-S31 PF15433.1 CDI77643.1 - 1.8 7.9 16.7 0.81 9.0 5.3 2.4 2 0 0 2 2 2 0 Mitochondrial 28S ribosomal protein S31 OmpH PF03938.9 CDI77643.1 - 3.6 7.5 38.5 0.43 10.4 13.3 3.7 3 0 0 3 3 3 0 Outer membrane protein (OmpH-like) Ctr PF04145.10 CDI77643.1 - 3.7 7.5 8.3 5.9 6.9 1.0 2.7 2 0 0 2 2 2 0 Ctr copper transporter family SR-25 PF10500.4 CDI77643.1 - 7.5 5.9 30.2 2.3 7.6 12.4 2.3 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Proteasome PF00227.21 CDI77650.1 - 3.1e-49 166.8 0.0 3.7e-49 166.5 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 CDI77650.1 - 3.8e-11 42.0 0.0 6.7e-11 41.3 0.0 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature DHC_N2 PF08393.8 CDI77652.1 - 2.1e-91 306.4 5.5 1.3e-64 218.2 0.0 7.3 7 1 1 8 8 8 3 Dynein heavy chain, N-terminal region 2 DHC_N1 PF08385.7 CDI77652.1 - 7.6e-91 305.2 10.3 7.6e-91 305.2 7.2 4.8 4 1 0 4 4 4 1 Dynein heavy chain, N-terminal region 1 AAA_6 PF12774.2 CDI77652.1 - 2.4e-84 282.4 0.3 3.4e-78 262.3 0.1 3.6 2 1 1 3 3 3 2 Hydrolytic ATP binding site of dynein motor region D1 AAA_8 PF12780.2 CDI77652.1 - 1.5e-73 247.0 0.1 4.2e-73 245.6 0.1 1.9 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_9 PF12781.2 CDI77652.1 - 7.2e-57 191.8 0.2 1.6e-56 190.6 0.1 1.6 1 0 0 1 1 1 1 ATP-binding dynein motor region D5 MT PF12777.2 CDI77652.1 - 1.3e-39 135.8 15.4 1.3e-39 135.8 10.7 2.7 4 0 0 4 4 3 1 Microtubule-binding stalk of dynein motor Dynein_heavy PF03028.10 CDI77652.1 - 1e-33 116.4 0.2 7.8e-33 113.4 0.1 2.3 1 1 0 1 1 1 1 Dynein heavy chain and region D6 of dynein motor AAA_7 PF12775.2 CDI77652.1 - 1e-18 67.3 0.0 3.3e-18 65.7 0.0 1.9 2 0 0 2 2 2 1 P-loop containing dynein motor region D3 AAA_5 PF07728.9 CDI77652.1 - 2.4e-14 53.2 0.1 3.5e-07 30.0 0.0 5.7 5 1 0 5 5 5 2 AAA domain (dynein-related subfamily) AAA PF00004.24 CDI77652.1 - 0.004 17.3 2.3 0.6 10.3 0.0 4.4 4 0 0 4 4 4 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 CDI77652.1 - 0.011 15.6 0.7 2.6 7.9 0.0 3.7 3 0 0 3 3 3 0 AAA domain RNA_helicase PF00910.17 CDI77652.1 - 0.024 14.8 0.6 11 6.2 0.0 3.9 3 0 0 3 3 3 0 RNA helicase AAA_17 PF13207.1 CDI77652.1 - 0.039 14.7 2.4 7.9 7.3 0.0 4.8 4 0 0 4 4 2 0 AAA domain AAA_29 PF13555.1 CDI77652.1 - 0.077 12.5 1.2 0.31 10.6 0.1 2.3 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_19 PF13245.1 CDI77652.1 - 0.1 12.3 3.1 16 5.2 0.1 3.4 3 0 0 3 3 3 0 Part of AAA domain EutH PF04346.7 CDI77652.1 - 3.5 6.4 0.0 6 5.7 0.0 1.2 1 0 0 1 1 1 0 Ethanolamine utilisation protein, EutH Dynein_heavy PF03028.10 CDI77653.1 - 8.5e-88 295.1 0.0 9.7e-88 294.9 0.0 1.0 1 0 0 1 1 1 1 Dynein heavy chain and region D6 of dynein motor Motilin_ghrelin PF04644.7 CDI77653.1 - 0.015 15.0 0.2 0.034 13.9 0.1 1.6 1 0 0 1 1 1 0 Motilin/ghrelin DnaB_bind PF10410.4 CDI77653.1 - 0.077 13.0 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 DnaB-helicase binding domain of primase Chorein_N PF12624.2 CDI77654.1 - 1.9e-22 78.9 0.0 4.3e-22 77.8 0.0 1.6 1 0 0 1 1 1 1 N-terminal region of Chorein, a TM vesicle-mediated sorter DUF1162 PF06650.7 CDI77654.1 - 7.9e-16 58.0 0.0 5.2e-15 55.3 0.0 2.3 1 1 0 1 1 1 1 Protein of unknown function (DUF1162) Lin0512_fam PF09585.5 CDI77654.1 - 0.022 14.3 0.0 0.13 11.8 0.0 2.1 2 0 0 2 2 2 0 Conserved hypothetical protein (Lin0512_fam) Choline_kinase PF01633.15 CDI77705.1 - 2.3e-16 60.0 0.1 6.7e-10 38.9 0.0 2.1 2 0 0 2 2 2 2 Choline/ethanolamine kinase APH PF01636.18 CDI77705.1 - 3e-05 23.8 0.0 6.9e-05 22.6 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF4557 PF15101.1 CDI77705.1 - 0.045 13.6 7.7 0.061 13.1 5.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) CBF_beta PF02312.12 CDI77705.1 - 0.094 12.3 5.1 0.14 11.7 3.5 1.1 1 0 0 1 1 1 0 Core binding factor beta subunit Fmp27 PF10344.4 CDI77705.1 - 0.55 7.8 5.6 0.71 7.4 3.9 1.1 1 0 0 1 1 1 0 Mitochondrial protein from FMP27 Folliculin PF11704.3 CDI77705.1 - 0.8 9.2 5.7 1.3 8.5 3.9 1.3 1 0 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport FimP PF09766.4 CDI77705.1 - 1.2 8.0 15.2 1.7 7.6 10.5 1.1 1 0 0 1 1 1 0 Fms-interacting protein DUF2951 PF11166.3 CDI77705.1 - 5.6 6.8 9.0 10 6.0 6.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2951) BAF1_ABF1 PF04684.8 CDI77705.1 - 7 5.3 18.7 9.8 4.8 13.0 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor HCO3_cotransp PF00955.16 CDI77720.1 - 0.0036 16.0 4.2 0.0037 15.9 2.9 1.0 1 0 0 1 1 1 1 HCO3- transporter family PBP1_TM PF14812.1 CDI77720.1 - 0.0094 16.2 6.3 0.012 15.9 4.3 1.1 1 0 0 1 1 1 1 Transmembrane domain of transglycosylase PBP1 at N-terminal Kei1 PF08552.6 CDI77720.1 - 0.01 15.5 9.9 0.012 15.2 6.9 1.0 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 SR-25 PF10500.4 CDI77720.1 - 0.033 13.6 12.8 0.039 13.4 8.9 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Peptidase_S49_N PF08496.5 CDI77720.1 - 0.033 13.9 13.6 0.043 13.6 9.5 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Peptidase_M56 PF05569.6 CDI77720.1 - 0.049 12.5 2.1 0.056 12.4 1.4 1.1 1 0 0 1 1 1 0 BlaR1 peptidase M56 DUF2370 PF10176.4 CDI77720.1 - 0.054 12.8 8.9 0.06 12.6 6.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) DUF2052 PF09747.4 CDI77720.1 - 0.06 13.2 20.2 0.063 13.2 14.0 1.1 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) HD-ZIP_N PF04618.7 CDI77720.1 - 0.061 13.8 9.4 0.075 13.5 6.5 1.1 1 0 0 1 1 1 0 HD-ZIP protein N terminus CDC45 PF02724.9 CDI77720.1 - 0.061 11.3 13.2 0.064 11.2 9.1 1.0 1 0 0 1 1 1 0 CDC45-like protein DUF4557 PF15101.1 CDI77720.1 - 0.064 13.1 29.1 0.076 12.8 20.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) FAM176 PF14851.1 CDI77720.1 - 0.068 12.8 7.6 0.078 12.6 5.3 1.2 1 0 0 1 1 1 0 FAM176 family DUF2561 PF10812.3 CDI77720.1 - 0.082 12.4 3.6 0.11 12.0 2.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2561) Serinc PF03348.10 CDI77720.1 - 0.11 11.2 14.4 0.12 11.1 10.0 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) DUF1632 PF07857.7 CDI77720.1 - 0.12 11.6 2.3 0.14 11.4 1.6 1.1 1 0 0 1 1 1 0 CEO family (DUF1632) Zip PF02535.17 CDI77720.1 - 0.13 11.1 4.5 0.15 11.0 3.1 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter DUF4366 PF14283.1 CDI77720.1 - 0.14 11.5 7.3 0.18 11.2 5.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) DUF4045 PF13254.1 CDI77720.1 - 0.14 11.4 12.9 0.15 11.3 8.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) PAT1 PF09770.4 CDI77720.1 - 0.15 10.2 45.9 0.16 10.1 31.8 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Ycf1 PF05758.7 CDI77720.1 - 0.16 9.6 16.3 0.16 9.6 11.3 1.0 1 0 0 1 1 1 0 Ycf1 Spore_coat_CotO PF14153.1 CDI77720.1 - 0.17 11.3 26.2 0.19 11.1 18.2 1.1 1 0 0 1 1 1 0 Spore coat protein CotO NARP1 PF12569.3 CDI77720.1 - 0.17 10.6 16.8 0.19 10.4 11.6 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Maf1 PF09174.5 CDI77720.1 - 0.17 11.7 9.3 0.2 11.5 6.4 1.1 1 0 0 1 1 1 0 Maf1 regulator Tim54 PF11711.3 CDI77720.1 - 0.2 10.2 11.2 0.21 10.1 7.8 1.0 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Cas1_AcylT PF07779.7 CDI77720.1 - 0.21 9.9 2.4 0.25 9.7 1.7 1.3 1 0 0 1 1 1 0 10 TM Acyl Transferase domain found in Cas1p DUF3464 PF11947.3 CDI77720.1 - 0.22 10.9 13.0 0.28 10.6 9.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) DUF2126 PF09899.4 CDI77720.1 - 0.22 9.4 12.3 0.23 9.4 8.5 1.0 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) Band_3_cyto PF07565.8 CDI77720.1 - 0.23 10.9 16.1 0.27 10.7 11.2 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Glyco_transf_15 PF01793.11 CDI77720.1 - 0.24 10.3 15.6 0.26 10.2 10.8 1.0 1 0 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase AIF_C PF14721.1 CDI77720.1 - 0.25 11.5 13.0 0.33 11.1 9.0 1.3 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Raftlin PF15250.1 CDI77720.1 - 0.31 9.4 16.3 0.36 9.2 11.3 1.0 1 0 0 1 1 1 0 Raftlin SpoIIP PF07454.6 CDI77720.1 - 0.32 10.1 12.9 0.35 10.0 8.9 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Folate_carrier PF01770.13 CDI77720.1 - 0.34 9.3 13.1 0.4 9.1 9.1 1.0 1 0 0 1 1 1 0 Reduced folate carrier Gti1_Pac2 PF09729.4 CDI77720.1 - 0.41 10.4 11.1 0.48 10.2 7.7 1.2 1 0 0 1 1 1 0 Gti1/Pac2 family DUF605 PF04652.11 CDI77720.1 - 0.44 9.8 24.0 0.45 9.8 16.7 1.0 1 0 0 1 1 1 0 Vta1 like DUF2407_C PF13373.1 CDI77720.1 - 0.45 10.4 8.6 0.59 10.0 5.9 1.3 1 0 0 1 1 1 0 DUF2407 C-terminal domain SUFU_C PF12470.3 CDI77720.1 - 0.46 10.0 9.6 0.56 9.7 6.6 1.0 1 0 0 1 1 1 0 Suppressor of Fused Gli/Ci N terminal binding domain eIF-3_zeta PF05091.7 CDI77720.1 - 0.47 9.0 24.8 0.52 8.8 17.2 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Spc7_N PF15402.1 CDI77720.1 - 0.48 8.3 17.8 0.48 8.3 12.3 1.0 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 Pex14_N PF04695.8 CDI77720.1 - 0.49 10.4 31.9 0.95 9.5 22.1 1.5 1 1 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region SID-1_RNA_chan PF13965.1 CDI77720.1 - 0.5 8.4 12.3 0.59 8.2 8.5 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 AUX_IAA PF02309.11 CDI77720.1 - 0.51 10.0 14.1 0.57 9.8 9.8 1.1 1 0 0 1 1 1 0 AUX/IAA family MDFI PF15316.1 CDI77720.1 - 0.55 10.1 9.0 0.69 9.8 6.3 1.1 1 0 0 1 1 1 0 MyoD family inhibitor RR_TM4-6 PF06459.7 CDI77720.1 - 0.57 10.0 18.9 0.64 9.8 13.1 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Pal1 PF08316.6 CDI77720.1 - 0.6 10.5 7.2 0.68 10.3 5.0 1.2 1 0 0 1 1 1 0 Pal1 cell morphology protein DUF1764 PF08576.5 CDI77720.1 - 0.6 10.9 19.7 0.91 10.3 13.7 1.3 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) DUF702 PF05142.7 CDI77720.1 - 0.65 10.1 15.8 0.78 9.9 10.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF702) DUF3700 PF12481.3 CDI77720.1 - 0.68 9.0 6.6 0.79 8.8 4.6 1.1 1 0 0 1 1 1 0 Aluminium induced protein RNA_pol_Rpb1_5 PF04998.12 CDI77720.1 - 0.73 9.0 10.0 0.75 8.9 6.9 1.0 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 DUF2828 PF11443.3 CDI77720.1 - 0.73 7.9 13.8 0.84 7.7 9.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) DHHW PF14286.1 CDI77720.1 - 0.75 9.0 13.5 0.81 8.9 9.4 1.0 1 0 0 1 1 1 0 DHHW protein RIC3 PF15361.1 CDI77720.1 - 0.76 10.0 17.2 1 9.5 11.9 1.1 1 0 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 DUF913 PF06025.7 CDI77720.1 - 0.79 8.4 8.9 0.79 8.4 6.2 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DUF1510 PF07423.6 CDI77720.1 - 0.79 9.0 21.4 0.94 8.7 14.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) AMP-binding PF00501.23 CDI77720.1 - 0.88 7.8 3.3 0.92 7.8 2.3 1.0 1 0 0 1 1 1 0 AMP-binding enzyme Nucleoside_tran PF01733.13 CDI77720.1 - 0.92 8.6 9.6 1.1 8.3 6.6 1.0 1 0 0 1 1 1 0 Nucleoside transporter TFIIA PF03153.8 CDI77720.1 - 0.92 9.3 34.8 0.93 9.3 24.1 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit TT_ORF1 PF02956.9 CDI77720.1 - 1 7.7 15.8 1 7.7 10.9 1.0 1 0 0 1 1 1 0 TT viral orf 1 UPF0565 PF10561.4 CDI77720.1 - 1.1 8.1 12.2 1.2 7.9 8.4 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0565 Peptidase_S15 PF02129.13 CDI77720.1 - 1.1 8.5 14.9 1.3 8.4 10.3 1.1 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) DUF3449 PF11931.3 CDI77720.1 - 1.2 8.6 19.9 1.4 8.3 13.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3449) OATP PF03137.15 CDI77720.1 - 1.2 7.0 15.3 1.7 6.6 10.6 1.3 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family AAA_11 PF13086.1 CDI77720.1 - 1.3 8.5 19.2 1.4 8.3 13.3 1.0 1 0 0 1 1 1 0 AAA domain Cellulose_synt PF03552.9 CDI77720.1 - 1.3 7.2 8.7 1.4 7.1 6.0 1.0 1 0 0 1 1 1 0 Cellulose synthase Bul1_N PF04425.7 CDI77720.1 - 1.3 7.4 16.3 1.5 7.2 11.3 1.0 1 0 0 1 1 1 0 Bul1 N terminus ETRAMP PF09716.5 CDI77720.1 - 1.3 8.9 6.9 6.3 6.8 4.8 1.9 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) CemA PF03040.9 CDI77720.1 - 1.4 8.5 11.2 1.6 8.3 7.8 1.0 1 0 0 1 1 1 0 CemA family Paramyxo_ncap PF00973.14 CDI77720.1 - 1.4 7.5 13.3 1.4 7.5 9.2 1.0 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein DUF3260 PF11658.3 CDI77720.1 - 1.4 6.9 17.3 1.5 6.9 12.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3260) FAM60A PF15396.1 CDI77720.1 - 1.4 8.5 14.2 1.6 8.3 9.8 1.1 1 0 0 1 1 1 0 Protein Family FAM60A DUF1675 PF07897.6 CDI77720.1 - 1.4 8.7 11.9 1.5 8.6 8.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) GAGA_bind PF06217.7 CDI77720.1 - 1.4 8.7 17.0 1.7 8.5 11.8 1.0 1 0 0 1 1 1 0 GAGA binding protein-like family Rtf2 PF04641.7 CDI77720.1 - 1.5 7.9 17.9 1.7 7.7 12.4 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger SeqA PF03925.8 CDI77720.1 - 1.5 8.4 15.6 1.9 8.1 10.8 1.2 1 0 0 1 1 1 0 SeqA protein FLO_LFY PF01698.11 CDI77720.1 - 1.5 7.5 17.2 1.8 7.3 11.9 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein DUF106 PF01956.11 CDI77720.1 - 1.5 8.2 16.6 1.8 8.0 11.5 1.1 1 0 0 1 1 1 0 Integral membrane protein DUF106 CPSF100_C PF13299.1 CDI77720.1 - 1.6 8.9 16.7 1.8 8.7 11.6 1.1 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Pap_E4 PF02711.9 CDI77720.1 - 1.7 9.4 14.6 2.4 9.0 10.1 1.3 1 0 0 1 1 1 0 E4 protein BTV_NS2 PF04514.7 CDI77720.1 - 1.8 7.3 15.2 1.9 7.2 10.5 1.0 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 MAT1 PF06391.8 CDI77720.1 - 1.8 8.1 27.2 2.2 7.8 18.9 1.2 1 0 0 1 1 1 0 CDK-activating kinase assembly factor MAT1 Fusion_gly_K PF01621.12 CDI77720.1 - 1.8 7.5 4.3 2.2 7.2 3.0 1.0 1 0 0 1 1 1 0 Cell fusion glycoprotein K GvpL_GvpF PF06386.6 CDI77720.1 - 1.8 8.0 15.9 2.2 7.8 11.0 1.3 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF DUF2269 PF10027.4 CDI77720.1 - 1.9 8.2 8.4 7.6 6.2 1.6 2.0 1 1 1 2 2 2 0 Predicted integral membrane protein (DUF2269) SPX PF03105.14 CDI77720.1 - 1.9 8.1 16.0 1.9 8.1 11.1 1.1 1 0 0 1 1 1 0 SPX domain UvrD_C_2 PF13538.1 CDI77720.1 - 2 8.5 9.5 2.6 8.2 6.6 1.2 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain Dynamin_N PF00350.18 CDI77720.1 - 2 8.1 10.4 2.8 7.7 7.2 1.3 1 0 0 1 1 1 0 Dynamin family DUF2072 PF09845.4 CDI77720.1 - 2.1 8.3 9.7 2.5 8.0 6.7 1.2 1 0 0 1 1 1 0 Zn-ribbon containing protein (DUF2072) Sec62 PF03839.11 CDI77720.1 - 2.1 7.6 13.8 2.3 7.5 9.6 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 SAGA-Tad1 PF12767.2 CDI77720.1 - 2.1 7.9 23.2 2.6 7.6 16.1 1.1 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit Ca_hom_mod PF14798.1 CDI77720.1 - 2.1 7.2 11.4 2.6 6.9 7.9 1.0 1 0 0 1 1 1 0 Calcium homeostasis modulator FemAB PF02388.11 CDI77720.1 - 2.2 6.8 20.1 2.5 6.7 13.9 1.1 1 0 0 1 1 1 0 FemAB family DUF3675 PF12428.3 CDI77720.1 - 2.2 8.5 10.1 3 8.1 7.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3675) Alg14 PF08660.6 CDI77720.1 - 2.3 8.1 6.5 2.9 7.8 4.5 1.2 1 0 0 1 1 1 0 Oligosaccharide biosynthesis protein Alg14 like NPR3 PF03666.8 CDI77720.1 - 2.3 6.6 16.8 2.7 6.4 11.6 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF3984 PF13136.1 CDI77720.1 - 2.4 7.2 13.4 2.7 7.1 9.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3984) Senescence_reg PF04520.8 CDI77720.1 - 2.7 8.4 10.4 2.8 8.4 7.2 1.1 1 0 0 1 1 1 0 Senescence regulator Peroxin-13_N PF04088.8 CDI77720.1 - 2.8 7.8 12.8 5.6 6.9 8.9 1.5 1 1 0 1 1 1 0 Peroxin 13, N-terminal region Neur_chan_memb PF02932.11 CDI77720.1 - 2.8 7.7 11.9 3.1 7.6 8.3 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region SpoVR PF04293.8 CDI77720.1 - 2.8 6.1 18.4 3.2 6.0 12.8 1.1 1 0 0 1 1 1 0 SpoVR like protein ABC2_membrane_2 PF12679.2 CDI77720.1 - 3 6.6 5.7 4.4 6.0 3.9 1.3 1 0 0 1 1 1 0 ABC-2 family transporter protein BORG_CEP PF14957.1 CDI77720.1 - 3.1 8.7 11.7 3.8 8.4 8.1 1.2 1 0 0 1 1 1 0 Cdc42 effector Shisa PF13908.1 CDI77720.1 - 3.5 7.7 20.6 3.7 7.6 14.3 1.1 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Presenilin PF01080.12 CDI77720.1 - 3.6 6.3 11.9 3.8 6.2 8.2 1.1 1 0 0 1 1 1 0 Presenilin DUF4220 PF13968.1 CDI77720.1 - 4.1 6.4 9.7 4.4 6.2 6.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4220) DUF1644 PF07800.7 CDI77720.1 - 4.2 7.2 16.7 69 3.2 11.6 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1644) DUF3604 PF12228.3 CDI77720.1 - 4.2 5.4 16.0 4.9 5.1 11.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3604) IncA PF04156.9 CDI77720.1 - 4.3 6.8 35.6 5.3 6.5 24.7 1.2 1 0 0 1 1 1 0 IncA protein DUF853 PF05872.7 CDI77720.1 - 4.7 5.4 16.0 5.3 5.2 11.1 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) DUF912 PF06024.7 CDI77720.1 - 4.8 7.2 19.8 1.1e+02 2.9 13.7 2.0 1 1 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Ctr PF04145.10 CDI77720.1 - 4.9 7.2 14.4 6.6 6.7 10.0 1.2 1 0 0 1 1 1 0 Ctr copper transporter family DUF4175 PF13779.1 CDI77720.1 - 5 4.7 58.5 5.8 4.4 40.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) DUF2058 PF09831.4 CDI77720.1 - 5.2 6.9 35.2 6.4 6.6 24.4 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2058) Glyco_transf_6 PF03414.8 CDI77720.1 - 5.3 5.4 12.1 6 5.2 8.4 1.1 1 0 0 1 1 1 0 Glycosyltransferase family 6 Plasmodium_Vir PF05795.6 CDI77720.1 - 5.3 6.1 7.7 5.4 6.1 5.4 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein GNT-I PF03071.10 CDI77720.1 - 5.5 5.4 14.0 5.9 5.3 9.7 1.0 1 0 0 1 1 1 0 GNT-I family COX6A PF02046.10 CDI77720.1 - 5.6 6.9 12.4 12 5.8 8.6 1.6 1 1 0 1 1 1 0 Cytochrome c oxidase subunit VIa DDHD PF02862.12 CDI77720.1 - 5.8 6.6 20.6 7.2 6.3 14.3 1.1 1 0 0 1 1 1 0 DDHD domain FYDLN_acid PF09538.5 CDI77720.1 - 6 7.5 13.9 8 7.1 9.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) Peptidase_U57 PF05582.7 CDI77720.1 - 6.1 5.7 16.4 7.5 5.4 11.4 1.1 1 0 0 1 1 1 0 YabG peptidase U57 Hid1 PF12722.2 CDI77720.1 - 6.2 4.3 21.5 6.9 4.2 14.9 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein PIH1 PF08190.7 CDI77720.1 - 7 5.9 25.2 7.8 5.8 17.5 1.0 1 0 0 1 1 1 0 pre-RNA processing PIH1/Nop17 DUF4446 PF14584.1 CDI77720.1 - 7.5 6.3 13.2 9 6.1 9.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) Spore_YhcN_YlaJ PF09580.5 CDI77720.1 - 7.6 6.6 21.7 8.8 6.4 15.1 1.1 1 0 0 1 1 1 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) 5_nucleotid PF05761.9 CDI77720.1 - 7.8 4.8 16.9 8.7 4.7 11.7 1.0 1 0 0 1 1 1 0 5' nucleotidase family YjgP_YjgQ PF03739.9 CDI77720.1 - 8.2 5.0 9.8 9.4 4.8 6.8 1.1 1 0 0 1 1 1 0 Predicted permease YjgP/YjgQ family ARD PF03079.9 CDI77720.1 - 8.3 6.3 10.6 11 5.9 7.3 1.1 1 0 0 1 1 1 0 ARD/ARD' family DUF822 PF05687.8 CDI77720.1 - 8.6 6.7 13.8 10 6.4 9.5 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF822) Mem_trans PF03547.13 CDI77720.1 - 8.7 4.5 8.0 9.5 4.3 5.6 1.2 1 0 0 1 1 1 0 Membrane transport protein DUF1800 PF08811.6 CDI77720.1 - 9.2 5.0 26.6 9.8 4.9 18.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1800) DDRGK PF09756.4 CDI77720.1 - 9.3 5.6 33.5 12 5.2 23.2 1.1 1 0 0 1 1 1 0 DDRGK domain G-7-MTase PF12803.2 CDI77720.1 - 9.8 5.2 10.7 10 5.1 7.4 1.1 1 0 0 1 1 1 0 mRNA (guanine-7-)methyltransferase (G-7-MTase) DIM1 PF02966.11 CDI77728.1 - 3.5e-67 223.9 0.5 4e-67 223.8 0.3 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin PF00085.15 CDI77728.1 - 0.0065 16.1 0.1 0.0084 15.7 0.1 1.2 1 0 0 1 1 1 1 Thioredoxin Orbi_VP3 PF01700.11 CDI77728.1 - 0.051 11.0 0.0 0.057 10.8 0.0 1.0 1 0 0 1 1 1 0 Orbivirus VP3 (T2) protein Herpes_UL56 PF04534.7 CDI77752.1 - 0.0019 17.9 0.0 0.003 17.3 0.0 1.3 1 0 0 1 1 1 1 Herpesvirus UL56 protein DUF4446 PF14584.1 CDI77760.1 - 0.94 9.2 0.0 0.94 9.2 0.0 4.6 6 0 0 6 6 6 0 Protein of unknown function (DUF4446) IncA PF04156.9 CDI77768.1 - 0.00061 19.4 5.0 0.00061 19.4 3.5 7.5 8 0 0 8 8 8 3 IncA protein FimP PF09766.4 CDI77768.1 - 0.00074 18.6 12.5 0.00074 18.6 8.6 6.7 5 2 2 7 7 7 2 Fms-interacting protein Dehydrin PF00257.14 CDI77775.1 - 0.0088 16.3 1.3 0.0088 16.3 0.9 3.6 2 1 0 2 2 2 1 Dehydrin EphA2_TM PF14575.1 CDI77775.1 - 2.6 8.5 5.0 1.8 8.9 0.8 2.8 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain SR-25 PF10500.4 CDI77806.1 - 1.9e-05 24.2 51.5 0.0047 16.4 20.6 2.4 2 0 0 2 2 2 2 Nuclear RNA-splicing-associated protein SOBP PF15279.1 CDI77806.1 - 0.48 10.7 17.1 0.66 10.3 11.8 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein DUF4231 PF14015.1 CDI77809.1 - 0.0012 18.7 0.9 0.0029 17.5 0.6 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF4231) DUF4179 PF13786.1 CDI77809.1 - 0.082 13.1 4.1 0.82 9.9 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4179) RskA PF10099.4 CDI77809.1 - 0.11 12.2 29.9 0.33 10.6 11.2 2.2 1 1 1 2 2 2 0 Anti-sigma-K factor rskA CD20 PF04103.10 CDI77809.1 - 0.22 11.4 0.0 0.22 11.4 0.0 2.7 2 1 0 2 2 1 0 CD20-like family Claudin_2 PF13903.1 CDI77809.1 - 0.49 10.0 10.1 1 9.0 7.0 1.6 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction DUF3381 PF11861.3 CDI77809.1 - 0.56 9.6 8.0 3 7.3 1.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3381) zf-DHHC PF01529.15 CDI77809.1 - 0.56 9.5 6.1 1.3 8.3 0.2 2.2 2 0 0 2 2 2 0 DHHC palmitoyltransferase Herpes_US9 PF06072.6 CDI77809.1 - 0.61 9.9 3.1 15 5.5 0.5 2.8 2 0 0 2 2 2 0 Alphaherpesvirus tegument protein US9 EphA2_TM PF14575.1 CDI77809.1 - 0.81 10.1 0.1 0.81 10.1 0.1 3.4 2 1 1 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain Sec62 PF03839.11 CDI77809.1 - 1.6 8.0 7.0 0.64 9.3 0.8 2.1 2 0 0 2 2 2 0 Translocation protein Sec62 DUF4366 PF14283.1 CDI77809.1 - 1.9 7.8 12.9 5.8 6.2 9.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4366) RAB3GAP2_N PF14655.1 CDI77809.1 - 1.9 7.3 20.1 1.4 7.8 3.4 2.1 1 1 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus DUF4386 PF14329.1 CDI77809.1 - 2.9 7.3 8.6 5.4 6.4 6.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4386) DUF605 PF04652.11 CDI77809.1 - 5.8 6.1 40.0 7.9 5.7 27.7 1.1 1 0 0 1 1 1 0 Vta1 like DUF533 PF04391.7 CDI77809.1 - 9.9 5.4 21.8 4.6 6.5 5.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF533) PRCC PF10253.4 CDI77816.1 - 0.07 13.8 22.3 0.083 13.5 15.5 1.0 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting Glyco_transf_15 PF01793.11 CDI77816.1 - 3.9 6.3 12.9 4.9 5.9 9.0 1.3 1 0 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase SWI-SNF_Ssr4 PF08549.5 CDI77827.1 - 0.2 9.9 5.6 0.23 9.7 3.9 1.0 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) MSP1_C PF07462.6 CDI77827.1 - 2.5 6.4 8.1 2.7 6.2 5.6 1.0 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus DUF3597 PF12200.3 CDI77827.1 - 4.9 7.5 6.9 6.9 7.0 4.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3597) Ank PF00023.25 CDI77845.1 - 0.0021 17.7 0.1 0.005 16.6 0.1 1.6 1 0 0 1 1 1 1 Ankyrin repeat MMR1 PF08505.5 CDI77845.1 - 0.0088 16.1 19.4 0.011 15.7 13.4 1.1 1 0 0 1 1 1 1 Mitochondrial Myo2 receptor-related protein Ank_2 PF12796.2 CDI77845.1 - 0.061 13.6 0.0 0.061 13.6 0.0 2.1 3 0 0 3 3 3 0 Ankyrin repeats (3 copies) PLRV_ORF5 PF01690.12 CDI77845.1 - 0.081 12.0 18.0 0.095 11.8 12.4 1.0 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein GPCR_chapero_1 PF11904.3 CDI77845.1 - 0.16 11.0 7.0 0.19 10.8 4.9 1.2 1 0 0 1 1 1 0 GPCR-chaperone DUF572 PF04502.8 CDI77845.1 - 0.27 10.4 18.6 0.34 10.0 12.9 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) CDK2AP PF09806.4 CDI77845.1 - 0.41 10.8 23.2 0.61 10.2 16.1 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein IER PF05760.7 CDI77845.1 - 0.79 9.5 27.4 1 9.2 19.0 1.0 1 0 0 1 1 1 0 Immediate early response protein (IER) Menin PF05053.8 CDI77845.1 - 1.6 6.7 11.5 2 6.4 8.0 1.1 1 0 0 1 1 1 0 Menin DUF4613 PF15390.1 CDI77845.1 - 2.2 6.3 11.0 2.8 6.0 7.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) Med15 PF09606.5 CDI77845.1 - 2.5 6.1 42.1 3.3 5.7 29.2 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal TFIIA PF03153.8 CDI77845.1 - 3.1 7.5 38.0 4.1 7.2 26.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit BSP_II PF05432.6 CDI77845.1 - 3.7 6.7 8.2 5.4 6.2 5.7 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Neur_chan_memb PF02932.11 CDI77845.1 - 4.4 7.1 12.8 5.8 6.7 8.8 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF966 PF06136.8 CDI77845.1 - 4.7 6.5 13.6 7.1 5.9 9.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Hid1 PF12722.2 CDI77845.1 - 6.1 4.3 13.1 7.1 4.1 9.1 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF605 PF04652.11 CDI77846.1 - 0.0072 15.7 36.1 0.011 15.1 25.0 1.3 1 0 0 1 1 1 1 Vta1 like SR-25 PF10500.4 CDI77846.1 - 0.019 14.4 23.1 0.038 13.4 16.0 1.5 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein PAT1 PF09770.4 CDI77846.1 - 0.099 10.8 76.2 0.13 10.4 52.8 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 CENP-T PF15511.1 CDI77846.1 - 0.19 10.9 34.8 0.31 10.2 24.2 1.3 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Ndc1_Nup PF09531.5 CDI77846.1 - 0.31 9.4 20.8 0.42 8.9 14.5 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup SARG PF15385.1 CDI77846.1 - 0.36 10.1 36.8 0.53 9.5 25.5 1.2 1 0 0 1 1 1 0 Specifically androgen-regulated gene protein DUF966 PF06136.8 CDI77846.1 - 2.6 7.3 26.6 3.7 6.8 18.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Asp-B-Hydro_N PF05279.6 CDI77846.1 - 7.3 6.3 33.9 12 5.6 23.5 1.3 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region gag-asp_proteas PF13975.1 CDI77879.1 - 4.7e-06 26.3 0.0 1e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 CDI77879.1 - 0.0027 18.1 0.0 0.0052 17.2 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease SAGA-Tad1 PF12767.2 CDI77889.1 - 0.0082 15.8 9.4 0.0086 15.7 6.5 1.2 1 0 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit DUF4175 PF13779.1 CDI77889.1 - 0.014 13.1 36.8 0.019 12.7 25.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) PAT1 PF09770.4 CDI77889.1 - 0.13 10.4 53.7 0.14 10.3 37.2 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 EPL1 PF10513.4 CDI77889.1 - 1.7 8.8 12.5 2.3 8.4 8.6 1.2 1 0 0 1 1 1 0 Enhancer of polycomb-like Peptidase_S15 PF02129.13 CDI77889.1 - 7.4 5.9 16.2 0.061 12.7 5.4 1.7 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) DUF2723 PF11028.3 CDI77890.1 - 0.12 11.7 1.7 0.15 11.5 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2723) N6_N4_Mtase PF01555.13 CDI77890.1 - 0.24 10.8 2.6 9.1 5.6 0.4 3.2 2 1 0 2 2 2 0 DNA methylase SelP_N PF04592.9 CDI77926.1 - 1.7 8.0 22.5 2 7.7 15.6 1.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region TCP PF03634.8 CDI77926.1 - 3 8.1 22.2 4 7.8 15.4 1.2 1 0 0 1 1 1 0 TCP family transcription factor Zip PF02535.17 CDI77926.1 - 3.4 6.5 14.0 4 6.3 9.7 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Bul1_N PF04425.7 CDI77926.1 - 4.6 5.6 20.7 5.5 5.4 14.4 1.1 1 0 0 1 1 1 0 Bul1 N terminus GAGA_bind PF06217.7 CDI77926.1 - 4.7 7.0 28.8 4.7 7.0 20.0 1.0 1 0 0 1 1 1 0 GAGA binding protein-like family FLO_LFY PF01698.11 CDI77926.1 - 4.9 5.9 28.6 5.4 5.7 19.8 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein ABC2_membrane_3 PF12698.2 CDI77927.1 - 4.6 6.1 9.0 6.3 5.7 6.2 1.4 1 0 0 1 1 1 0 ABC-2 family transporter protein HECT PF00632.20 CDI77954.1 - 2.4e-58 197.8 0.0 4.9e-58 196.7 0.0 1.5 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) GILT PF03227.11 CDI77954.1 - 8.3e-18 64.2 0.1 2e-17 63.0 0.0 1.6 1 0 0 1 1 1 1 Gamma interferon inducible lysosomal thiol reductase (GILT) UPF0220 PF05255.6 CDI77955.1 - 0.1 11.8 0.1 0.21 10.8 0.1 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0220) Neur_chan_memb PF02932.11 CDI77962.1 - 0.97 9.2 32.9 1.4 8.7 22.8 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Ycf1 PF05758.7 CDI77962.1 - 0.98 7.0 36.8 1.3 6.6 25.5 1.1 1 0 0 1 1 1 0 Ycf1 CDC45 PF02724.9 CDI77962.1 - 3.2 5.6 38.4 3.8 5.4 26.6 1.1 1 0 0 1 1 1 0 CDC45-like protein AAA_12 PF13087.1 CDI77964.1 - 7.5e-36 123.3 0.1 7.5e-36 123.3 0.1 3.5 2 1 0 2 2 2 1 AAA domain PAT1 PF09770.4 CDI77977.1 - 0.001 17.4 102.7 0.0012 17.1 71.2 1.1 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 CDC27 PF09507.5 CDI77977.1 - 0.088 12.0 46.0 0.11 11.6 31.9 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 AAA_23 PF13476.1 CDI77984.1 - 0.00013 22.3 22.0 0.00018 21.9 15.3 1.1 1 0 0 1 1 1 1 AAA domain DUF1682 PF07946.9 CDI77984.1 - 0.00096 18.0 7.3 0.0011 17.8 5.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) DUF2244 PF10003.4 CDI77984.1 - 0.042 13.2 2.0 0.12 11.7 1.4 1.8 1 0 0 1 1 1 0 Integral membrane protein (DUF2244) DUF2207 PF09972.4 CDI77988.1 - 0.0059 15.2 2.5 0.0066 15.0 1.7 1.2 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) TrkH PF02386.11 CDI77988.1 - 0.3 9.5 2.2 0.29 9.6 1.6 1.2 1 0 0 1 1 1 0 Cation transport protein ABC2_membrane_3 PF12698.2 CDI77988.1 - 0.41 9.6 12.6 0.52 9.2 8.8 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein Tweety PF04906.8 CDI77988.1 - 0.46 8.8 23.3 0.53 8.6 16.2 1.0 1 0 0 1 1 1 0 Tweety DUF3899 PF13038.1 CDI77988.1 - 0.53 10.4 3.3 1.2 9.3 2.3 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF3899) DUF912 PF06024.7 CDI77988.1 - 0.82 9.7 14.9 15 5.7 10.4 2.1 1 1 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Peptidase_M56 PF05569.6 CDI77988.1 - 0.97 8.3 7.2 1.9 7.4 5.0 1.6 1 1 0 1 1 1 0 BlaR1 peptidase M56 DUF3753 PF12575.3 CDI77988.1 - 0.98 9.2 3.9 0.31 10.8 0.6 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3753) HCO3_cotransp PF00955.16 CDI77988.1 - 1.4 7.4 7.7 1.6 7.2 5.3 1.0 1 0 0 1 1 1 0 HCO3- transporter family DUF3357 PF11837.3 CDI77988.1 - 2.1 8.2 6.0 0.73 9.7 2.1 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF3357) PAT1 PF09770.4 CDI77988.1 - 2.7 6.1 43.9 2.7 6.1 30.4 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF3708 PF12501.3 CDI77988.1 - 3.5 7.4 11.0 4.7 7.0 7.6 1.2 1 0 0 1 1 1 0 Phosphate ATP-binding cassette transporter CD20 PF04103.10 CDI77988.1 - 3.5 7.5 9.9 10 6.0 6.9 1.7 1 1 0 1 1 1 0 CD20-like family DUF3619 PF12279.3 CDI77988.1 - 4.4 7.3 18.9 5.8 7.0 13.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3619) YjgP_YjgQ PF03739.9 CDI77988.1 - 5.8 5.5 16.2 6.7 5.3 11.2 1.1 1 0 0 1 1 1 0 Predicted permease YjgP/YjgQ family RNA_pol_Rpb1_2 PF00623.15 CDI77988.1 - 7.3 6.5 9.8 9 6.2 6.8 1.1 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 2 DUF3492 PF11997.3 CDI77988.1 - 7.5 6.0 11.2 8 5.9 7.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3492) Scs3p PF10261.4 CDI77988.1 - 7.6 5.4 7.1 6.7 5.6 4.0 1.6 1 1 1 2 2 2 0 Inositol phospholipid synthesis and fat-storage-inducing TM Pex24p PF06398.6 CDI77988.1 - 8.8 5.0 8.2 11 4.6 5.7 1.2 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin Spatacsin_C PF14649.1 CDI78009.1 - 2.9e-07 29.6 11.1 0.001 17.9 7.3 2.4 2 0 0 2 2 2 2 Spatacsin C-terminus DUF1571 PF07608.6 CDI78009.1 - 0.13 11.4 0.0 0.21 10.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1571) PDEase_I PF00233.14 CDI78024.1 - 4.1e-51 174.0 0.1 6.7e-51 173.3 0.1 1.4 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase CDK2AP PF09806.4 CDI78024.1 - 0.0087 16.3 5.8 0.03 14.5 4.0 1.9 1 0 0 1 1 1 1 Cyclin-dependent kinase 2-associated protein HD PF01966.17 CDI78024.1 - 0.016 15.1 0.2 0.045 13.7 0.1 1.7 1 0 0 1 1 1 0 HD domain K_channel_TID PF07941.6 CDI78024.1 - 0.051 13.8 14.0 0.16 12.2 9.7 1.8 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain DUF4407 PF14362.1 CDI78024.1 - 0.29 10.0 8.1 0.72 8.7 5.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) VIT1 PF01988.14 CDI78024.1 - 0.32 10.4 5.5 1 8.7 3.8 1.9 1 1 0 1 1 1 0 VIT family Spt20 PF12090.3 CDI78024.1 - 0.63 9.3 6.9 2.4 7.4 0.7 2.4 2 0 0 2 2 2 0 Spt20 family Pex14_N PF04695.8 CDI78024.1 - 1.9 8.5 10.8 0.78 9.7 0.7 2.8 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Prefoldin PF02996.12 CDI78029.1 - 3.2e-18 65.5 1.2 1.8e-17 63.0 0.8 1.9 1 1 0 1 1 1 1 Prefoldin subunit GCV_T PF01571.16 CDI78029.1 - 0.0061 15.9 0.1 0.011 15.1 0.0 1.4 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain Transferase PF02458.10 CDI78029.1 - 0.096 11.1 0.4 0.16 10.3 0.1 1.4 2 0 0 2 2 2 0 Transferase family TPR_11 PF13414.1 CDI78032.1 - 9.8e-05 21.9 0.5 0.0014 18.2 0.1 2.7 1 1 1 2 2 2 2 TPR repeat DUF3626 PF12294.3 CDI78033.1 - 0.0034 16.4 0.0 0.46 9.4 0.0 2.7 2 1 0 2 2 2 1 Protein of unknown function (DUF3626) ERbeta_N PF12497.3 CDI78033.1 - 0.26 11.1 3.8 0.14 12.0 0.4 2.3 2 0 0 2 2 2 0 Estrogen receptor beta OmpH PF03938.9 CDI78034.1 - 5e-09 36.2 22.7 5e-09 36.2 15.7 5.5 4 1 0 4 4 4 1 Outer membrane protein (OmpH-like) SprA-related PF12118.3 CDI78034.1 - 5.7e-07 29.1 22.2 5.7e-07 29.1 15.4 8.8 8 2 1 9 9 9 1 SprA-related family Ycf1 PF05758.7 CDI78034.1 - 0.00079 17.2 4.5 0.00079 17.2 3.1 3.3 3 1 0 3 3 3 1 Ycf1 IncA PF04156.9 CDI78034.1 - 0.0021 17.6 3.0 0.0021 17.6 2.1 6.6 5 1 1 6 6 6 1 IncA protein SseC PF04888.7 CDI78034.1 - 0.0035 16.7 28.9 0.0035 16.7 20.0 7.1 7 1 0 7 7 7 1 Secretion system effector C (SseC) like family Med15 PF09606.5 CDI78037.1 - 0.023 12.9 78.1 0.033 12.4 54.1 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal PAT1 PF09770.4 CDI78037.1 - 7.2 4.7 72.8 9.1 4.3 50.5 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Hid1 PF12722.2 CDI78046.1 - 0.042 11.5 5.2 0.041 11.5 3.6 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein FAM176 PF14851.1 CDI78046.1 - 0.86 9.2 7.1 1.6 8.4 4.9 1.4 1 0 0 1 1 1 0 FAM176 family DDHD PF02862.12 CDI78046.1 - 1.2 8.8 6.9 2.1 8.0 4.8 1.5 1 0 0 1 1 1 0 DDHD domain PBP1_TM PF14812.1 CDI78046.1 - 2.9 8.2 5.5 5.5 7.3 3.8 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Methyltransf_14 PF08484.6 CDI78054.1 - 1.8 8.1 5.7 4.7 6.7 4.0 1.7 1 0 0 1 1 1 0 C-methyltransferase C-terminal domain Tetraspannin PF00335.15 CDI78062.1 - 0.00099 18.4 1.7 0.00099 18.4 1.2 4.0 1 1 1 2 2 2 1 Tetraspanin family DUF3260 PF11658.3 CDI78062.1 - 0.0061 14.7 0.4 0.0061 14.7 0.3 4.4 2 2 1 4 4 4 1 Protein of unknown function (DUF3260) DUF1510 PF07423.6 CDI78062.1 - 0.007 15.7 22.7 0.007 15.7 15.7 5.1 2 2 3 5 5 5 1 Protein of unknown function (DUF1510) DUF4063 PF13272.1 CDI78062.1 - 0.69 9.7 0.0 0.69 9.7 0.0 4.9 2 1 0 2 2 2 0 Protein of unknown function (DUF4063) Ribosomal_60s PF00428.14 CDI78068.1 - 0.017 15.5 2.1 0.025 14.9 1.5 1.3 1 0 0 1 1 1 0 60s Acidic ribosomal protein Zip PF02535.17 CDI78068.1 - 2.6 6.9 8.9 3.8 6.4 6.1 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter PAT1 PF09770.4 CDI78069.1 - 2.9 6.0 79.4 3.3 5.8 55.1 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Ribosomal_60s PF00428.14 CDI78077.1 - 5.1 7.5 21.7 3.8 7.9 4.3 3.6 4 0 0 4 4 4 0 60s Acidic ribosomal protein DUF1180 PF06679.7 CDI78078.1 - 0.021 14.7 2.0 0.021 14.7 1.4 2.6 1 1 1 3 3 3 0 Protein of unknown function (DUF1180) TRAP_alpha PF03896.11 CDI78078.1 - 0.022 13.7 0.3 0.035 13.1 0.2 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit AUX_IAA PF02309.11 CDI78078.1 - 0.084 12.6 4.8 0.13 11.9 3.3 1.3 1 0 0 1 1 1 0 AUX/IAA family DUF702 PF05142.7 CDI78078.1 - 0.28 11.3 8.6 0.7 10.0 6.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF702) TFIIA PF03153.8 CDI78078.1 - 0.5 10.2 15.2 0.73 9.6 10.6 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Spore_YhcN_YlaJ PF09580.5 CDI78078.1 - 0.65 10.0 7.6 0.86 9.6 5.2 1.1 1 0 0 1 1 1 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) Gag_spuma PF03276.9 CDI78078.1 - 5.6 5.1 15.4 8 4.6 10.6 1.2 1 0 0 1 1 1 0 Spumavirus gag protein DUF4131 PF13567.1 CDI78078.1 - 8.4 5.7 10.2 1.5 8.1 2.8 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) DUF3943 PF13084.1 CDI78090.1 - 0.063 12.8 0.3 20 4.8 0.0 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3943) IncA PF04156.9 CDI78105.1 - 7e-07 29.0 11.7 7e-07 29.0 8.1 2.1 2 0 0 2 2 2 1 IncA protein MFS_2 PF13347.1 CDI78105.1 - 0.058 11.7 0.0 0.091 11.1 0.0 1.3 1 0 0 1 1 1 0 MFS/sugar transport protein DUF3357 PF11837.3 CDI78106.1 - 0.073 12.9 2.9 0.38 10.6 0.2 2.3 1 1 0 2 2 2 0 Domain of unknown function (DUF3357) Plant_vir_prot PF01307.12 CDI78106.1 - 0.087 12.5 0.0 0.23 11.1 0.0 1.8 1 1 0 1 1 1 0 Plant viral movement protein RskA PF10099.4 CDI78106.1 - 0.93 9.2 23.6 0.067 12.9 7.0 2.2 1 1 0 2 2 2 0 Anti-sigma-K factor rskA FimP PF09766.4 CDI78107.1 - 0.0035 16.4 5.4 0.0035 16.4 3.7 6.8 5 1 2 7 7 7 2 Fms-interacting protein SAPS PF04499.10 CDI78107.1 - 0.0061 15.2 0.2 0.0061 15.2 0.1 4.9 4 1 0 4 4 4 1 SIT4 phosphatase-associated protein Plasmodium_Vir PF05795.6 CDI78108.1 - 0.0023 17.2 10.4 0.34 10.0 8.2 2.1 1 1 1 2 2 2 2 Plasmodium vivax Vir protein DUF1510 PF07423.6 CDI78108.1 - 0.0056 16.0 18.4 0.0056 16.0 12.8 2.6 3 0 0 3 3 3 2 Protein of unknown function (DUF1510) PDR_CDR PF06422.7 CDI78108.1 - 0.0063 16.1 0.3 0.0063 16.1 0.2 2.7 2 1 0 2 2 2 1 CDR ABC transporter Pox_P21 PF05313.7 CDI78108.1 - 3.9 6.7 7.1 0.2 10.9 0.2 2.1 2 0 0 2 2 2 0 Poxvirus P21 membrane protein Peptidase_M56 PF05569.6 CDI78108.1 - 8.9 5.1 11.7 0.061 12.2 1.1 2.1 1 1 1 2 2 2 0 BlaR1 peptidase M56 Spt20 PF12090.3 CDI78111.1 - 0.0059 15.9 0.9 0.011 15.1 0.6 1.6 1 0 0 1 1 1 1 Spt20 family AAA_33 PF13671.1 CDI78118.1 - 0.0072 16.1 0.1 0.012 15.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.1 CDI78120.1 - 4.3 7.6 10.1 7.6 6.7 7.0 1.4 1 0 0 1 1 1 0 AAA domain Adipogenin PF15202.1 CDI78121.1 - 0.059 13.2 2.4 0.74 9.7 1.1 2.3 2 0 0 2 2 2 0 Adipogenin PGA2 PF07543.7 CDI78121.1 - 0.16 11.7 0.0 0.16 11.7 0.0 2.0 2 0 0 2 2 2 0 Protein trafficking PGA2 FAM163 PF15069.1 CDI78121.1 - 0.25 11.9 4.4 0.43 11.1 0.1 2.5 2 1 0 2 2 2 0 FAM163 family Tmemb_9 PF05434.6 CDI78121.1 - 0.53 10.0 2.4 0.54 9.9 0.2 2.1 2 1 0 2 2 2 0 TMEM9 PRA1 PF03208.14 CDI78121.1 - 1.1 8.5 5.8 0.16 11.2 0.6 2.1 3 0 0 3 3 3 0 PRA1 family protein TRAP_alpha PF03896.11 CDI78121.1 - 1.3 7.9 4.2 0.61 9.0 0.8 1.8 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit Med3 PF11593.3 CDI78138.1 - 0.95 8.6 9.6 1.2 8.2 6.7 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Ribosomal_60s PF00428.14 CDI78143.1 - 0.25 11.7 0.1 0.25 11.7 0.1 5.9 5 1 0 5 5 5 0 60s Acidic ribosomal protein RAB3GAP2_N PF14655.1 CDI78143.1 - 2.8 6.8 12.2 3.1 6.6 3.0 2.5 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus DDHD PF02862.12 CDI78172.1 - 0.016 15.0 7.0 0.3 10.8 0.7 2.8 2 1 0 2 2 2 0 DDHD domain Chorion_2 PF03964.10 CDI78172.1 - 0.05 14.1 0.1 0.05 14.1 0.0 5.5 4 1 1 5 5 5 0 Chorion family 2 DUF778 PF05608.7 CDI78172.1 - 0.16 11.8 0.0 0.46 10.4 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF778) Rxt3 PF08642.5 CDI78172.1 - 3 8.1 6.0 7.3 6.8 0.8 2.7 3 0 0 3 3 3 0 Histone deacetylation protein Rxt3 FimP PF09766.4 CDI78172.1 - 3.9 6.4 21.6 0.16 11.0 4.7 2.3 2 0 0 2 2 2 0 Fms-interacting protein Pex14_N PF04695.8 CDI78172.1 - 8.3 6.4 25.4 13 5.8 6.8 3.4 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region PEX11 PF05648.9 CDI78172.1 - 9 5.4 13.4 1.2 8.3 1.3 2.6 3 0 0 3 3 3 0 Peroxisomal biogenesis factor 11 (PEX11) FHIPEP PF00771.15 CDI78172.1 - 9.1 4.4 15.8 0.062 11.6 0.9 2.9 3 0 0 3 3 3 0 FHIPEP family EphA2_TM PF14575.1 CDI78289.1 - 5.8 7.3 10.2 3.8 7.9 0.0 3.7 4 1 0 4 4 4 0 Ephrin type-A receptor 2 transmembrane domain FLO_LFY PF01698.11 CDI78290.1 - 0.23 10.2 13.0 0.23 10.2 9.0 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein Zip PF02535.17 CDI78290.1 - 0.38 9.6 2.1 0.44 9.5 1.5 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Med15 PF09606.5 CDI78290.1 - 1.5 6.9 73.3 1.7 6.7 50.8 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Ycf1 PF05758.7 CDI78290.1 - 2.9 5.5 21.7 3.2 5.3 15.1 1.0 1 0 0 1 1 1 0 Ycf1 AAA_23 PF13476.1 CDI78290.1 - 2.9 8.1 20.3 4 7.7 14.1 1.2 1 0 0 1 1 1 0 AAA domain MRP-S31 PF15433.1 CDI78290.1 - 7.4 5.8 25.7 9.7 5.5 17.8 1.2 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 PAT1 PF09770.4 CDI78290.1 - 8.3 4.5 58.0 8.6 4.4 40.2 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 MIP-T3 PF10243.4 CDI78312.1 - 0.32 9.4 53.7 0.36 9.2 37.2 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Polysacc_deac_1 PF01522.16 CDI78313.1 - 0.97 9.0 3.2 0.93 9.1 1.5 1.4 1 1 0 1 1 1 0 Polysaccharide deacetylase SprA-related PF12118.3 CDI78313.1 - 2.9 7.1 53.5 4 6.6 37.1 1.2 1 0 0 1 1 1 0 SprA-related family PAT1 PF09770.4 CDI78318.1 - 0.0011 17.3 26.5 0.0014 17.0 18.4 1.2 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 Fungal_trans_2 PF11951.3 CDI78318.1 - 0.056 12.0 8.4 0.19 10.2 0.7 2.2 2 0 0 2 2 2 0 Fungal specific transcription factor domain Herpes_UL87 PF03043.9 CDI78318.1 - 0.064 11.6 2.5 0.063 11.6 1.8 1.2 1 0 0 1 1 1 0 Herpesvirus UL87 family PRP1_N PF06424.7 CDI78318.1 - 0.08 13.2 12.7 0.12 12.6 8.8 1.3 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal Mem_trans PF03547.13 CDI78318.1 - 0.11 10.7 1.4 0.14 10.4 0.9 1.3 1 0 0 1 1 1 0 Membrane transport protein PLRV_ORF5 PF01690.12 CDI78318.1 - 0.2 10.7 11.2 0.25 10.4 7.8 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Cwf_Cwc_15 PF04889.7 CDI78318.1 - 0.23 11.1 19.2 0.32 10.6 13.3 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein CDC45 PF02724.9 CDI78318.1 - 0.74 7.7 15.1 0.91 7.4 10.5 1.1 1 0 0 1 1 1 0 CDC45-like protein Hid1 PF12722.2 CDI78318.1 - 0.87 7.1 14.3 1 6.9 9.9 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Ycf1 PF05758.7 CDI78318.1 - 2.7 5.5 15.1 3.4 5.2 10.4 1.1 1 0 0 1 1 1 0 Ycf1 Ndc1_Nup PF09531.5 CDI78318.1 - 2.8 6.2 7.3 3.4 5.9 5.1 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Sulfatase_C PF14707.1 CDI78318.1 - 2.9 8.1 9.6 6.5 7.0 6.6 1.5 1 0 0 1 1 1 0 C-terminal region of aryl-sulfatase DUF1675 PF07897.6 CDI78318.1 - 3.2 7.5 10.4 5.5 6.7 7.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) GET2 PF08690.5 CDI78318.1 - 3.7 6.6 12.3 5.2 6.2 8.5 1.2 1 0 0 1 1 1 0 GET complex subunit GET2 DUF4207 PF13904.1 CDI78318.1 - 4.1 6.7 35.8 6.4 6.0 24.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4207) Asp-B-Hydro_N PF05279.6 CDI78318.1 - 8 6.2 18.7 12 5.6 12.9 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Paramyxo_ncap PF00973.14 CDI78318.1 - 9.9 4.7 16.9 17 3.9 11.7 1.3 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Baculo_PP31 PF05311.6 CDI78321.1 - 0.0061 15.8 0.1 0.01 15.1 0.0 1.3 1 0 0 1 1 1 1 Baculovirus 33KDa late protein (PP31) Gly-zipper_OmpA PF13436.1 CDI78321.1 - 0.016 14.8 1.2 0.016 14.8 0.8 7.0 6 2 2 8 8 8 0 Glycine-zipper containing OmpA-like membrane domain Suf PF05843.9 CDI78321.1 - 0.021 14.5 7.6 0.034 13.8 5.3 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) PAT1 PF09770.4 CDI78321.1 - 0.29 9.3 32.7 0.51 8.5 22.7 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 FimP PF09766.4 CDI78321.1 - 4.7 6.1 21.2 6.7 5.6 14.7 1.1 1 0 0 1 1 1 0 Fms-interacting protein DUF4220 PF13968.1 CDI78321.1 - 6 5.8 5.8 10 5.1 4.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4220) RskA PF10099.4 CDI78329.1 - 0.0017 18.1 7.7 0.0022 17.7 5.3 1.1 1 0 0 1 1 1 1 Anti-sigma-K factor rskA FimP PF09766.4 CDI78329.1 - 0.0056 15.8 13.5 0.0056 15.8 9.3 1.0 1 0 0 1 1 1 1 Fms-interacting protein DUF4557 PF15101.1 CDI78329.1 - 0.049 13.4 15.2 0.056 13.2 10.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) HemX PF04375.9 CDI78329.1 - 0.075 11.6 17.0 0.082 11.4 11.8 1.0 1 0 0 1 1 1 0 HemX FHIPEP PF00771.15 CDI78329.1 - 0.11 10.7 4.6 0.12 10.6 3.2 1.0 1 0 0 1 1 1 0 FHIPEP family Activator_LAG-3 PF11498.3 CDI78329.1 - 0.18 10.4 30.7 0.17 10.6 21.3 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 zf-DHHC PF01529.15 CDI78329.1 - 0.28 10.5 2.3 0.25 10.7 1.6 1.1 1 0 0 1 1 1 0 DHHC palmitoyltransferase Suf PF05843.9 CDI78329.1 - 0.34 10.6 12.9 0.32 10.7 9.0 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Peptidase_S49_N PF08496.5 CDI78329.1 - 0.66 9.7 6.3 0.61 9.8 4.4 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Shadoo PF14999.1 CDI78329.1 - 0.85 9.4 6.0 1 9.2 4.2 1.2 1 0 0 1 1 1 0 Shadow of prion protein, neuroprotective DUF788 PF05620.6 CDI78329.1 - 1.1 9.0 8.6 1.2 8.9 5.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF788) Spt20 PF12090.3 CDI78329.1 - 1.2 8.4 14.2 1.3 8.2 9.8 1.2 1 0 0 1 1 1 0 Spt20 family OATP PF03137.15 CDI78329.1 - 1.5 6.7 4.8 1.3 6.9 3.3 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Band_3_cyto PF07565.8 CDI78329.1 - 1.7 8.0 8.1 1.8 8.0 5.6 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Serinc PF03348.10 CDI78329.1 - 1.9 7.0 8.4 1.8 7.1 5.8 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) Folate_carrier PF01770.13 CDI78329.1 - 2.5 6.5 4.8 2.4 6.5 3.4 1.1 1 0 0 1 1 1 0 Reduced folate carrier TALPID3 PF15324.1 CDI78329.1 - 2.6 5.2 15.7 2.8 5.1 10.9 1.0 1 0 0 1 1 1 0 Hedgehog signalling target Peptidase_S15 PF02129.13 CDI78329.1 - 3.8 6.8 10.5 4.3 6.6 7.3 1.1 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) R_equi_Vir PF05526.6 CDI78329.1 - 4.1 6.9 7.9 4.8 6.7 5.5 1.1 1 0 0 1 1 1 0 Rhodococcus equi virulence-associated protein PAT1 PF09770.4 CDI78329.1 - 4.9 5.2 27.1 4.6 5.3 18.8 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TFIIA PF03153.8 CDI78329.1 - 6.3 6.5 23.1 7 6.4 16.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Usp PF00582.21 CDI78329.1 - 6.5 6.9 6.0 8.2 6.6 4.2 1.1 1 0 0 1 1 1 0 Universal stress protein family DUF1980 PF09323.5 CDI78329.1 - 9 5.9 7.4 11 5.7 5.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) Auto_anti-p27 PF06677.7 CDI78332.1 - 5.5e-12 45.2 0.2 9.6e-12 44.4 0.2 1.4 1 0 0 1 1 1 1 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) TFIIA PF03153.8 CDI78332.1 - 0.0035 17.2 43.3 0.0044 16.9 30.0 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit SR-25 PF10500.4 CDI78332.1 - 0.22 10.9 23.9 0.084 12.3 5.9 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein DUF429 PF04250.8 CDI78332.1 - 0.29 10.3 4.7 0.28 10.4 2.3 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF429) IncA PF04156.9 CDI78332.1 - 0.37 10.3 40.9 0.31 10.6 19.3 2.4 2 0 0 2 2 2 0 IncA protein PLRV_ORF5 PF01690.12 CDI78332.1 - 0.8 8.7 22.6 1.2 8.1 15.6 1.3 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein FAM60A PF15396.1 CDI78332.1 - 0.81 9.3 23.1 1.8 8.2 1.6 2.3 2 0 0 2 2 2 0 Protein Family FAM60A DUF2052 PF09747.4 CDI78332.1 - 1.1 9.1 35.8 1.8 8.4 12.6 2.2 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) Ndc1_Nup PF09531.5 CDI78332.1 - 2.1 6.6 21.6 2.6 6.3 15.0 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Oxysterol_BP PF01237.13 CDI78342.1 - 4.5e-20 71.4 0.0 2.4e-15 55.9 0.0 5.1 4 1 0 5 5 5 2 Oxysterol-binding protein PH PF00169.24 CDI78342.1 - 1.4e-10 41.2 0.3 3.8e-10 39.9 0.2 1.8 1 0 0 1 1 1 1 PH domain SprA-related PF12118.3 CDI78342.1 - 0.0031 16.8 51.4 0.0031 16.8 35.7 9.8 3 2 3 6 6 6 1 SprA-related family SOBP PF15279.1 CDI78342.1 - 0.0037 17.6 24.3 0.0037 17.6 16.9 6.4 2 1 3 5 5 5 1 Sine oculis-binding protein Pox_Ag35 PF03286.9 CDI78344.1 - 0.00032 20.2 6.9 0.00032 20.2 4.8 2.6 3 0 0 3 3 3 1 Pox virus Ag35 surface protein RAP1 PF07218.6 CDI78344.1 - 0.14 10.2 8.3 0.011 13.9 0.8 2.0 2 0 0 2 2 2 0 Rhoptry-associated protein 1 (RAP-1) Peptidase_S46 PF10459.4 CDI78344.1 - 2.4 6.4 30.6 3.5 5.9 21.2 1.1 1 0 0 1 1 1 0 Peptidase S46 Spore_coat_CotO PF14153.1 CDI78344.1 - 3.6 7.0 41.9 1.3 8.4 19.1 2.3 2 0 0 2 2 2 0 Spore coat protein CotO Membralin PF09746.4 CDI78344.1 - 6.9 5.5 16.2 0.8 8.6 7.7 1.8 1 1 1 2 2 2 0 Tumour-associated protein DUF605 PF04652.11 CDI78428.1 - 2.3 7.5 40.2 3 7.1 27.9 1.1 1 0 0 1 1 1 0 Vta1 like DivIC PF04977.10 CDI78428.1 - 2.7 7.5 10.7 4 6.9 7.4 1.3 1 0 0 1 1 1 0 Septum formation initiator CCDC84 PF14968.1 CDI78428.1 - 5.1 6.4 26.1 6 6.2 18.1 1.0 1 0 0 1 1 1 0 Coiled coil protein 84 Dicty_REP PF05086.7 CDI78475.1 - 0.021 12.6 30.2 0.024 12.4 21.0 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein MIP-T3 PF10243.4 CDI78475.1 - 0.021 13.3 54.6 0.025 13.0 37.8 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Utp14 PF04615.8 CDI78475.1 - 0.057 11.5 51.9 0.066 11.3 36.0 1.0 1 0 0 1 1 1 0 Utp14 protein Macoilin PF09726.4 CDI78475.1 - 0.14 10.3 53.7 0.18 10.0 37.2 1.1 1 0 0 1 1 1 0 Transmembrane protein Med15 PF09606.5 CDI78475.1 - 0.27 9.4 117.9 0.32 9.1 81.7 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF2413 PF10310.4 CDI78475.1 - 2.1 7.1 51.1 3.1 6.5 35.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) PAT1 PF09770.4 CDI78475.1 - 2.7 6.1 104.2 3.1 5.9 72.2 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF966 PF06136.8 CDI78475.1 - 3.4 7.0 45.0 4.7 6.5 31.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF966) PLRV_ORF5 PF01690.12 CDI78475.1 - 5.5 6.0 42.9 6.7 5.7 29.7 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Birna_RdRp PF04197.7 CDI78475.1 - 7.8 4.3 23.3 8.8 4.2 16.2 1.0 1 0 0 1 1 1 0 Birnavirus RNA dependent RNA polymerase (VP1) Asp-B-Hydro_N PF05279.6 CDI78475.1 - 8.5 6.1 43.6 11 5.8 30.2 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region CAF-1_p150 PF11600.3 CDI78534.1 - 0.026 13.8 47.3 0.036 13.4 32.8 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal GAGA_bind PF06217.7 CDI78534.1 - 0.31 10.9 34.1 0.38 10.6 23.6 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family SOBP PF15279.1 CDI78534.1 - 0.38 11.0 32.0 0.43 10.9 22.2 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein Utp14 PF04615.8 CDI78534.1 - 0.56 8.3 43.7 0.62 8.1 30.3 1.1 1 0 0 1 1 1 0 Utp14 protein Med15 PF09606.5 CDI78534.1 - 0.9 7.6 97.1 1 7.4 67.3 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Parvo_coat PF00740.13 CDI78534.1 - 4.9 5.9 38.9 5.2 5.8 27.0 1.1 1 0 0 1 1 1 0 Parvovirus coat protein VP2 FimP PF09766.4 CDI78545.1 - 0.00083 18.5 6.2 0.00083 18.5 4.3 10.3 5 2 4 9 9 9 2 Fms-interacting protein tRNA-synt_1 PF00133.17 CDI78555.1 - 2.3e-66 224.0 0.0 5.5e-28 97.3 0.0 5.5 5 1 0 5 5 5 5 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 CDI78555.1 - 9.6e-20 70.8 0.0 2.1e-19 69.7 0.0 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 CDI78555.1 - 2.2e-10 39.7 0.9 1.2e-07 30.7 0.0 3.4 4 0 0 4 4 4 2 tRNA synthetases class I (M) DUF2012 PF09430.5 CDI78557.1 - 8.5e-10 38.5 0.0 1.2e-09 38.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2012) IncA PF04156.9 CDI78557.1 - 0.014 14.9 0.5 0.026 14.1 0.3 1.3 1 0 0 1 1 1 0 IncA protein OTU PF02338.14 CDI78559.1 - 1.1e-12 48.5 0.0 3.8e-12 46.8 0.0 2.0 2 0 0 2 2 2 1 OTU-like cysteine protease Peptidase_C65 PF10275.4 CDI78559.1 - 0.00065 19.1 0.1 0.0041 16.5 0.1 2.0 1 1 1 2 2 2 1 Peptidase C65 Otubain VWA PF00092.23 CDI78561.1 - 3.1e-38 131.2 0.0 4.5e-38 130.7 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain TSP_1 PF00090.14 CDI78561.1 - 1.3e-24 86.0 66.1 3.9e-09 36.4 1.9 7.2 6 1 0 6 6 6 5 Thrombospondin type 1 domain VWA_2 PF13519.1 CDI78561.1 - 1.1e-14 54.8 0.0 2e-14 54.0 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.1 CDI78561.1 - 0.0036 17.0 0.0 0.0061 16.2 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain vWA-TerF-like PF10138.4 CDI78561.1 - 0.17 11.6 0.0 0.29 10.9 0.0 1.3 1 0 0 1 1 1 0 vWA found in TerF C terminus NRN1 PF15056.1 CDI78561.1 - 8 6.4 8.1 13 5.7 0.2 2.9 3 0 0 3 3 3 0 Neuritin protein family DUF2457 PF10446.4 CDI78571.1 - 0.017 13.9 30.7 0.018 13.8 21.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Kei1 PF08552.6 CDI78571.1 - 0.022 14.4 1.1 0.026 14.2 0.8 1.0 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 DUF912 PF06024.7 CDI78571.1 - 0.063 13.3 0.2 0.079 13.0 0.1 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Zip PF02535.17 CDI78571.1 - 0.1 11.6 6.5 0.1 11.5 4.5 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter DUF913 PF06025.7 CDI78571.1 - 0.31 9.7 6.1 0.29 9.8 4.3 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DUF2058 PF09831.4 CDI78571.1 - 0.32 10.8 11.3 0.38 10.6 7.9 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2058) TRAP_alpha PF03896.11 CDI78571.1 - 0.35 9.8 19.6 0.35 9.8 13.6 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit SURF6 PF04935.7 CDI78571.1 - 0.43 9.8 21.8 0.46 9.7 15.1 1.0 1 0 0 1 1 1 0 Surfeit locus protein 6 NPR3 PF03666.8 CDI78571.1 - 0.54 8.7 11.5 0.65 8.4 7.9 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF2052 PF09747.4 CDI78571.1 - 0.75 9.6 26.8 0.8 9.5 18.6 1.1 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) DUF3306 PF11748.3 CDI78571.1 - 0.77 10.4 18.5 0.91 10.1 12.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3306) Raftlin PF15250.1 CDI78571.1 - 0.85 8.0 9.8 0.87 8.0 6.8 1.0 1 0 0 1 1 1 0 Raftlin FGF-BP1 PF06473.7 CDI78571.1 - 1 8.9 10.3 1.1 8.7 7.2 1.0 1 0 0 1 1 1 0 FGF binding protein 1 (FGF-BP1) OATP PF03137.15 CDI78571.1 - 1.1 7.2 3.0 1.1 7.2 2.1 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Paf1 PF03985.8 CDI78571.1 - 1.3 7.6 35.1 1.6 7.4 24.4 1.0 1 0 0 1 1 1 0 Paf1 Nucleoside_tran PF01733.13 CDI78571.1 - 1.4 8.0 6.8 1.5 7.9 4.7 1.2 1 0 0 1 1 1 0 Nucleoside transporter Folate_carrier PF01770.13 CDI78571.1 - 1.5 7.2 6.1 1.5 7.2 4.2 1.1 1 0 0 1 1 1 0 Reduced folate carrier DUF1168 PF06658.7 CDI78571.1 - 1.6 8.2 24.8 1.9 7.9 17.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) Rtf2 PF04641.7 CDI78571.1 - 2 7.5 12.7 2.3 7.3 8.8 1.0 1 0 0 1 1 1 0 Rtf2 RING-finger DUF3449 PF11931.3 CDI78571.1 - 2 7.8 17.3 2.1 7.8 12.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3449) BUD22 PF09073.5 CDI78571.1 - 2 7.3 27.4 2.4 7.1 19.0 1.0 1 0 0 1 1 1 0 BUD22 DUF3408 PF11888.3 CDI78571.1 - 2.1 8.2 15.6 2.4 8.1 10.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) SpoIIIAH PF12685.2 CDI78571.1 - 2.1 7.8 15.1 2.2 7.7 10.5 1.0 1 0 0 1 1 1 0 SpoIIIAH-like protein RR_TM4-6 PF06459.7 CDI78571.1 - 2.3 8.0 21.6 2.5 7.9 15.0 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Vfa1 PF08432.5 CDI78571.1 - 2.3 8.2 21.2 2.7 7.9 14.7 1.0 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Glyco_transf_15 PF01793.11 CDI78571.1 - 2.3 7.0 8.6 2.5 6.9 6.0 1.0 1 0 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase EIIBC-GUT_N PF03612.9 CDI78571.1 - 2.4 7.7 5.5 2.7 7.5 3.8 1.1 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Serinc PF03348.10 CDI78571.1 - 2.5 6.7 6.9 2.7 6.6 4.8 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) Spore_coat_CotO PF14153.1 CDI78571.1 - 2.8 7.3 29.7 3.4 7.0 20.6 1.0 1 0 0 1 1 1 0 Spore coat protein CotO Tim54 PF11711.3 CDI78571.1 - 2.8 6.4 17.2 3.2 6.2 12.0 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 RRN3 PF05327.6 CDI78571.1 - 2.9 5.9 16.2 2.9 5.8 11.2 1.0 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Sigma70_ner PF04546.8 CDI78571.1 - 2.9 7.4 25.3 3.6 7.1 17.5 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region FAM60A PF15396.1 CDI78571.1 - 3 7.5 5.4 3.2 7.4 3.7 1.0 1 0 0 1 1 1 0 Protein Family FAM60A DDHD PF02862.12 CDI78571.1 - 3 7.5 16.8 3.3 7.4 11.7 1.0 1 0 0 1 1 1 0 DDHD domain Pox_Ag35 PF03286.9 CDI78571.1 - 3.1 7.2 23.1 4.3 6.8 16.0 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein RP-C_C PF11800.3 CDI78571.1 - 3.3 7.3 10.0 3.6 7.2 7.0 1.0 1 0 0 1 1 1 0 Replication protein C C-terminal region DUF3899 PF13038.1 CDI78571.1 - 3.4 7.9 12.1 0.32 11.1 0.9 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF3899) AIF_C PF14721.1 CDI78571.1 - 3.5 7.8 9.8 4.1 7.6 6.8 1.1 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term DUF2828 PF11443.3 CDI78571.1 - 3.8 5.5 5.8 3.8 5.6 4.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Cnd2 PF05786.9 CDI78571.1 - 3.9 5.8 12.1 3.7 5.9 8.4 1.2 1 0 0 1 1 1 0 Condensin complex subunit 2 Upf2 PF04050.9 CDI78571.1 - 3.9 7.2 27.9 4.3 7.0 19.3 1.1 1 0 0 1 1 1 0 Up-frameshift suppressor 2 Nop14 PF04147.7 CDI78571.1 - 4.4 5.1 36.0 5 4.9 25.0 1.0 1 0 0 1 1 1 0 Nop14-like family POX PF07526.6 CDI78571.1 - 5.2 7.2 8.0 6.1 7.0 5.5 1.1 1 0 0 1 1 1 0 Associated with HOX DUF4246 PF14033.1 CDI78571.1 - 5.2 5.5 15.4 5.4 5.4 10.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4246) DDRGK PF09756.4 CDI78571.1 - 6 6.2 35.5 6.8 6.0 24.6 1.0 1 0 0 1 1 1 0 DDRGK domain TFIIA PF03153.8 CDI78571.1 - 6.7 6.4 23.0 7.5 6.3 15.9 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit NARP1 PF12569.3 CDI78571.1 - 6.8 5.3 17.5 7.1 5.2 12.1 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DUF3530 PF12048.3 CDI78571.1 - 7.3 5.4 12.3 7.8 5.3 8.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) DUF4011 PF13195.1 CDI78571.1 - 7.6 6.5 9.8 9.1 6.2 6.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4011) PRP21_like_P PF12230.3 CDI78571.1 - 8.4 5.8 20.6 12 5.3 14.3 1.3 1 0 0 1 1 1 0 Pre-mRNA splicing factor PRP21 like protein FYDLN_acid PF09538.5 CDI78571.1 - 8.6 6.9 22.4 12 6.5 15.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) Tankyrase_bdg_C PF15327.1 CDI78571.1 - 9 6.4 13.0 14 5.8 9.0 1.3 1 0 0 1 1 1 0 Tankyrase binding protein C terminal domain SID-1_RNA_chan PF13965.1 CDI78571.1 - 9.4 4.2 8.2 9.7 4.2 5.7 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Plasmodium_Vir PF05795.6 CDI78571.1 - 9.6 5.2 11.1 12 5.0 7.7 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Gag_spuma PF03276.9 CDI78588.1 - 0.00046 18.6 18.5 0.00048 18.6 12.8 1.0 1 0 0 1 1 1 1 Spumavirus gag protein Serinc PF03348.10 CDI78588.1 - 0.00057 18.7 2.9 0.00063 18.5 2.0 1.1 1 0 0 1 1 1 1 Serine incorporator (Serinc) AIF_C PF14721.1 CDI78588.1 - 0.00082 19.6 2.5 0.00094 19.4 1.7 1.2 1 0 0 1 1 1 1 Apoptosis-inducing factor, mitochondrion-associated, C-term DUF2076 PF09849.4 CDI78588.1 - 0.002 18.2 17.7 0.0021 18.1 12.3 1.0 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) FimP PF09766.4 CDI78588.1 - 0.0031 16.6 18.1 0.0033 16.5 12.6 1.1 1 0 0 1 1 1 1 Fms-interacting protein CDC45 PF02724.9 CDI78588.1 - 0.0053 14.8 2.5 0.0052 14.8 1.8 1.0 1 0 0 1 1 1 1 CDC45-like protein OATP PF03137.15 CDI78588.1 - 0.0064 14.5 1.7 0.0049 14.9 1.2 1.1 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family Folate_carrier PF01770.13 CDI78588.1 - 0.0077 14.7 1.0 0.0073 14.8 0.7 1.1 1 0 0 1 1 1 1 Reduced folate carrier DUF913 PF06025.7 CDI78588.1 - 0.0096 14.7 1.2 0.0094 14.7 0.8 1.0 1 0 0 1 1 1 1 Domain of Unknown Function (DUF913) FHIPEP PF00771.15 CDI78588.1 - 0.014 13.7 1.7 0.012 13.9 1.2 1.1 1 0 0 1 1 1 0 FHIPEP family FLO_LFY PF01698.11 CDI78588.1 - 0.017 13.9 5.4 0.019 13.8 3.7 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein Peptidase_U57 PF05582.7 CDI78588.1 - 0.023 13.6 2.8 0.025 13.5 1.9 1.1 1 0 0 1 1 1 0 YabG peptidase U57 DUF3260 PF11658.3 CDI78588.1 - 0.025 12.7 3.7 0.024 12.7 2.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3260) Peptidase_S15 PF02129.13 CDI78588.1 - 0.033 13.6 5.1 0.034 13.5 3.5 1.1 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Tim54 PF11711.3 CDI78588.1 - 0.036 12.6 2.6 0.039 12.5 1.8 1.0 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 zf-DHHC PF01529.15 CDI78588.1 - 0.04 13.3 1.6 0.044 13.1 1.1 1.2 1 0 0 1 1 1 0 DHHC palmitoyltransferase AUX_IAA PF02309.11 CDI78588.1 - 0.046 13.4 5.4 0.05 13.3 3.8 1.1 1 0 0 1 1 1 0 AUX/IAA family YABBY PF04690.8 CDI78588.1 - 0.049 13.8 1.2 0.053 13.7 0.9 1.1 1 0 0 1 1 1 0 YABBY protein DDHD PF02862.12 CDI78588.1 - 0.056 13.2 6.3 0.063 13.0 4.4 1.1 1 0 0 1 1 1 0 DDHD domain GvpL_GvpF PF06386.6 CDI78588.1 - 0.067 12.7 7.0 0.081 12.5 4.8 1.1 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF PIH1 PF08190.7 CDI78588.1 - 0.082 12.3 11.8 0.087 12.2 8.2 1.0 1 0 0 1 1 1 0 pre-RNA processing PIH1/Nop17 AAA_23 PF13476.1 CDI78588.1 - 0.087 13.1 12.0 0.088 13.1 8.3 1.1 1 0 0 1 1 1 0 AAA domain Baculo_PP31 PF05311.6 CDI78588.1 - 0.093 11.9 8.9 0.11 11.7 6.2 1.1 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) Nucleoside_tran PF01733.13 CDI78588.1 - 0.11 11.7 0.5 0.11 11.6 0.4 1.2 1 0 0 1 1 1 0 Nucleoside transporter Suf PF05843.9 CDI78588.1 - 0.13 11.9 16.4 0.16 11.6 11.4 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) U1snRNP70_N PF12220.3 CDI78588.1 - 0.15 12.3 12.9 0.2 11.9 9.0 1.2 1 0 0 1 1 1 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal Rtf2 PF04641.7 CDI78588.1 - 0.17 11.0 8.3 0.2 10.8 5.8 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger DUF3573 PF12097.3 CDI78588.1 - 0.18 10.4 5.8 0.17 10.4 4.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) SAGA-Tad1 PF12767.2 CDI78588.1 - 0.21 11.2 11.9 0.22 11.1 8.2 1.1 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit DUF702 PF05142.7 CDI78588.1 - 0.22 11.7 9.1 0.29 11.2 6.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF702) EIIBC-GUT_N PF03612.9 CDI78588.1 - 0.24 10.9 6.9 0.28 10.7 4.8 1.1 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus PAT1 PF09770.4 CDI78588.1 - 0.27 9.4 30.3 0.3 9.2 21.0 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Pan_kinase PF03309.9 CDI78588.1 - 0.29 10.6 3.3 0.47 9.9 2.3 1.3 1 0 0 1 1 1 0 Type III pantothenate kinase DUF4557 PF15101.1 CDI78588.1 - 0.33 10.7 21.4 0.39 10.5 14.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) CPSF100_C PF13299.1 CDI78588.1 - 0.37 10.9 7.0 0.42 10.7 4.9 1.1 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Pex14_N PF04695.8 CDI78588.1 - 0.38 10.7 19.8 0.51 10.3 13.7 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Band_3_cyto PF07565.8 CDI78588.1 - 0.4 10.1 10.7 0.55 9.7 7.4 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain DUF3408 PF11888.3 CDI78588.1 - 0.43 10.4 8.4 0.52 10.2 5.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) MDFI PF15316.1 CDI78588.1 - 0.46 10.4 2.8 0.56 10.1 1.9 1.2 1 0 0 1 1 1 0 MyoD family inhibitor CagX PF03524.10 CDI78588.1 - 0.5 9.6 8.5 0.64 9.2 5.9 1.2 1 0 0 1 1 1 0 Conjugal transfer protein Med15 PF09606.5 CDI78588.1 - 0.54 8.3 44.9 0.6 8.2 31.1 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF1764 PF08576.5 CDI78588.1 - 0.59 10.9 12.6 0.79 10.5 8.7 1.2 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) DUF3306 PF11748.3 CDI78588.1 - 0.61 10.7 10.8 0.8 10.3 7.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3306) Dala_Dala_lig_N PF01820.16 CDI78588.1 - 0.61 10.4 4.4 0.8 10.0 3.0 1.2 1 0 0 1 1 1 0 D-ala D-ala ligase N-terminus TFIIA PF03153.8 CDI78588.1 - 0.68 9.7 21.5 0.76 9.6 14.9 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CRF1 PF10380.4 CDI78588.1 - 0.76 10.1 6.4 0.89 9.8 4.5 1.1 1 0 0 1 1 1 0 Transcription factor CRF1 Peroxin-13_N PF04088.8 CDI78588.1 - 0.76 9.7 5.9 1 9.3 4.1 1.2 1 0 0 1 1 1 0 Peroxin 13, N-terminal region DUF4199 PF13858.1 CDI78588.1 - 0.87 9.4 11.5 0.2 11.6 6.0 1.5 2 0 0 2 2 1 0 Protein of unknown function (DUF4199) Gti1_Pac2 PF09729.4 CDI78588.1 - 0.96 9.3 7.1 1.2 9.0 4.9 1.1 1 0 0 1 1 1 0 Gti1/Pac2 family NARP1 PF12569.3 CDI78588.1 - 1.1 7.9 11.5 1.3 7.7 8.0 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 RR_TM4-6 PF06459.7 CDI78588.1 - 1.2 9.0 11.1 1.4 8.7 7.7 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 FAM60A PF15396.1 CDI78588.1 - 1.2 8.8 7.3 1.4 8.5 5.0 1.1 1 0 0 1 1 1 0 Protein Family FAM60A DUF3464 PF11947.3 CDI78588.1 - 1.2 8.5 9.4 1.8 8.0 6.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) HCV_NS5a_C PF12941.2 CDI78588.1 - 1.4 8.4 4.1 1.7 8.1 2.8 1.1 1 0 0 1 1 1 0 HCV NS5a protein C-terminal region SprA-related PF12118.3 CDI78588.1 - 1.4 8.1 31.3 1.7 7.9 21.7 1.0 1 0 0 1 1 1 0 SprA-related family Neur_chan_memb PF02932.11 CDI78588.1 - 1.5 8.6 7.2 1.7 8.4 3.8 1.7 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Hid1 PF12722.2 CDI78588.1 - 1.6 6.3 11.7 1.8 6.1 8.1 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Ctr PF04145.10 CDI78588.1 - 1.7 8.7 7.4 2.4 8.2 5.2 1.3 1 0 0 1 1 1 0 Ctr copper transporter family SeqA PF03925.8 CDI78588.1 - 1.8 8.1 10.3 2.2 7.9 7.1 1.1 1 0 0 1 1 1 0 SeqA protein Kei1 PF08552.6 CDI78588.1 - 1.9 8.0 9.3 2.7 7.6 6.4 1.2 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 Spc7_N PF15402.1 CDI78588.1 - 2.3 6.1 13.1 2.4 6.0 9.1 1.0 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 ATAD4 PF15321.1 CDI78588.1 - 2.3 9.2 12.7 3 8.9 8.8 1.1 1 0 0 1 1 1 0 ATPase family AAA domain containing 4 DUF3675 PF12428.3 CDI78588.1 - 2.5 8.3 4.7 3.4 7.9 3.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3675) DUF853 PF05872.7 CDI78588.1 - 2.5 6.3 9.9 2.9 6.1 6.8 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) DDRGK PF09756.4 CDI78588.1 - 2.6 7.4 18.2 3.3 7.0 12.6 1.1 1 0 0 1 1 1 0 DDRGK domain RED_N PF07808.8 CDI78588.1 - 2.9 7.0 22.9 3.4 6.8 15.9 1.1 1 0 0 1 1 1 0 RED-like protein N-terminal region DUF605 PF04652.11 CDI78588.1 - 3.1 7.1 18.2 3.7 6.8 12.6 1.0 1 0 0 1 1 1 0 Vta1 like BRF1 PF07741.8 CDI78588.1 - 3.3 7.9 13.1 4.6 7.5 9.1 1.1 1 0 0 1 1 1 0 Brf1-like TBP-binding domain FCP1_C PF09309.5 CDI78588.1 - 3.7 6.7 16.5 6.7 5.9 11.4 1.3 1 0 0 1 1 1 0 FCP1, C-terminal Glyco_transf_15 PF01793.11 CDI78588.1 - 4 6.2 11.2 5 5.9 7.7 1.1 1 0 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase UPF0560 PF10577.4 CDI78588.1 - 4.5 5.4 20.8 4.9 5.2 14.4 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 FAM176 PF14851.1 CDI78588.1 - 4.8 6.8 7.8 0.94 9.1 3.3 1.3 2 0 0 2 2 1 0 FAM176 family TMEM51 PF15345.1 CDI78588.1 - 4.8 6.8 16.7 6.3 6.4 11.6 1.1 1 0 0 1 1 1 0 Transmembrane protein 51 Bud13 PF09736.4 CDI78588.1 - 7.1 6.8 18.8 9 6.5 13.0 1.1 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex DUF912 PF06024.7 CDI78588.1 - 7.2 6.7 11.4 0.19 11.8 3.8 1.5 2 0 0 2 2 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) G0-G1_switch_2 PF15103.1 CDI78588.1 - 8.1 6.7 9.8 13 6.0 6.8 1.4 1 0 0 1 1 1 0 G0/G1 switch protein 2 DUF4175 PF13779.1 CDI78588.1 - 8.2 3.9 41.1 10 3.6 28.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Paramyxo_ncap PF00973.14 CDI78588.1 - 8.8 4.8 8.7 10 4.6 6.0 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Med15 PF09606.5 CDI78590.1 - 0.068 11.3 42.1 0.08 11.1 29.2 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal SR-25 PF10500.4 CDI78590.1 - 0.31 10.4 21.9 0.4 10.0 15.2 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein SprA-related PF12118.3 CDI78590.1 - 0.35 10.1 47.5 0.55 9.5 32.9 1.2 1 0 0 1 1 1 0 SprA-related family Corona_nucleoca PF00937.13 CDI78590.1 - 0.81 8.5 25.8 1 8.2 17.9 1.2 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein DUF966 PF06136.8 CDI78590.1 - 1.4 8.2 24.9 1.9 7.8 17.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Pox_E2-like PF04497.7 CDI78590.1 - 1.7 6.6 5.1 1.8 6.4 3.5 1.0 1 0 0 1 1 1 0 Poxviridae protein DUF1675 PF07897.6 CDI78590.1 - 4.5 7.0 26.1 5.5 6.7 18.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) PA26 PF04636.8 CDI78590.1 - 7.3 5.1 14.7 9 4.8 10.2 1.0 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) GPCR_chapero_1 PF11904.3 CDI78590.1 - 7.7 5.5 18.7 9.3 5.2 13.0 1.2 1 0 0 1 1 1 0 GPCR-chaperone GAGA_bind PF06217.7 CDI78590.1 - 8.1 6.3 22.8 10 5.9 15.8 1.0 1 0 0 1 1 1 0 GAGA binding protein-like family PAT1 PF09770.4 CDI78590.1 - 9.4 4.3 36.9 11 4.1 25.6 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Activator_LAG-3 PF11498.3 CDI78595.1 - 0.00037 19.3 27.5 0.00037 19.3 19.1 3.6 4 1 0 4 4 4 2 Transcriptional activator LAG-3 Pkinase PF00069.20 CDI78653.1 - 1.1e-12 47.6 0.7 1.9e-12 46.9 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDI78653.1 - 1.8e-06 27.2 0.7 3.4e-06 26.3 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase DUF1566 PF07603.6 CDI78653.1 - 0.1 12.3 0.1 0.17 11.6 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1566) Pkinase PF00069.20 CDI78657.1 - 4.9e-20 71.7 0.0 9e-20 70.9 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDI78657.1 - 0.00053 19.1 0.0 0.0011 18.0 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Metallophos PF00149.23 CDI78660.1 - 0.015 14.7 0.0 0.021 14.2 0.0 1.3 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase Cas_DxTHG PF09455.5 CDI78662.1 - 0.22 10.6 2.8 0.31 10.1 2.0 1.2 1 0 0 1 1 1 0 CRISPR-associated (Cas) DxTHG family DUF883 PF05957.8 CDI78662.1 - 0.42 11.0 12.1 3.6 8.0 2.3 3.2 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF883) Aconitase_B_N PF11791.3 CDI78662.1 - 3.3 7.5 8.4 0.38 10.5 0.6 2.3 2 0 0 2 2 2 0 Aconitate B N-terminal domain PP_kinase_N PF13089.1 CDI78662.1 - 7.2 6.7 16.6 4.6 7.3 3.5 2.7 2 0 0 2 2 2 0 Polyphosphate kinase N-terminal domain TMPIT PF07851.8 CDI78662.1 - 9.4 5.1 18.5 2.1 7.3 4.0 2.3 2 0 0 2 2 2 0 TMPIT-like protein Spt20 PF12090.3 CDI78665.1 - 0.88 8.8 11.1 17 4.7 0.0 3.8 4 0 0 4 4 4 0 Spt20 family PPI_Ypi1 PF07491.6 CDI78666.1 - 6.1e-21 73.8 0.1 1e-20 73.1 0.0 1.4 1 0 0 1 1 1 1 Protein phosphatase inhibitor MTBP_C PF14920.1 CDI78666.1 - 0.0072 15.8 5.6 0.009 15.5 3.9 1.2 1 0 0 1 1 1 1 MDM2-binding SR-25 PF10500.4 CDI78666.1 - 0.026 13.9 2.2 0.029 13.8 1.6 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Pkinase PF00069.20 CDI78667.1 - 2.5e-15 56.3 0.0 4.5e-14 52.2 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.1 CDI78667.1 - 7.8e-15 54.5 0.0 3.4e-14 52.4 0.0 1.9 1 1 0 1 1 1 1 Kinase-like Pkinase_Tyr PF07714.12 CDI78667.1 - 1.2e-06 27.8 0.0 1.9e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 CDI78669.1 - 6.9e-13 48.3 0.0 3.4e-12 46.0 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.1 CDI78669.1 - 2.3e-09 36.6 0.0 4.2e-09 35.7 0.0 1.3 1 1 0 1 1 1 1 Kinase-like Pkinase_Tyr PF07714.12 CDI78669.1 - 7.7e-05 21.8 0.0 0.00012 21.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase DUF4229 PF14012.1 CDI78669.1 - 0.054 13.4 0.3 0.11 12.3 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4229) DUF3591 PF12157.3 CDI78673.1 - 4.1e-19 68.3 0.0 2.3e-14 52.6 0.0 3.2 2 1 0 2 2 2 2 Protein of unknown function (DUF3591) Bromodomain PF00439.20 CDI78673.1 - 2.1e-14 53.1 0.0 4.1e-14 52.2 0.0 1.4 1 0 0 1 1 1 1 Bromodomain DUF1487 PF07368.6 CDI78673.1 - 0.18 11.0 0.0 0.34 10.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1487) Hormone_4 PF00220.12 CDI78673.1 - 0.43 10.3 4.3 0.51 10.1 0.2 2.6 2 0 0 2 2 2 0 Neurohypophysial hormones, N-terminal Domain Patched PF02460.13 CDI78675.1 - 2.7e-87 293.5 10.5 1.3e-51 175.4 0.2 3.7 3 1 0 3 3 3 2 Patched family Sterol-sensing PF12349.3 CDI78675.1 - 7.4e-28 96.9 4.9 7.4e-28 96.9 3.4 2.3 2 0 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation ACR_tran PF00873.14 CDI78675.1 - 2.7e-05 21.8 10.5 6.1e-05 20.6 7.3 1.5 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family Ank PF00023.25 CDI78676.1 - 1.8e-27 93.7 16.6 9.5e-08 31.4 0.0 8.9 9 1 0 9 9 9 7 Ankyrin repeat Ank_2 PF12796.2 CDI78676.1 - 2.5e-24 85.3 9.6 4.7e-05 23.6 0.5 5.5 3 2 3 6 6 6 6 Ankyrin repeats (3 copies) Ank_3 PF13606.1 CDI78676.1 - 5.7e-16 57.0 11.3 2.1e-05 24.3 0.0 8.3 9 0 0 9 9 9 3 Ankyrin repeat Ank_4 PF13637.1 CDI78676.1 - 7.6e-15 54.9 6.5 0.0029 18.0 0.0 6.7 5 2 0 5 5 5 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 CDI78676.1 - 2e-11 43.7 10.0 0.0013 18.9 0.0 7.6 5 3 2 8 8 8 3 Ankyrin repeats (many copies) LRR19-TM PF15176.1 CDI78677.1 - 0.11 12.2 0.0 0.24 11.0 0.0 1.6 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain Herpes_gE PF02480.11 CDI78677.1 - 0.67 8.1 0.0 0.67 8.1 0.0 1.9 2 0 0 2 2 2 0 Alphaherpesvirus glycoprotein E Med15 PF09606.5 CDI78678.1 - 9.4e-05 20.8 47.1 9.4e-05 20.8 32.6 2.6 2 1 0 2 2 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal PAT1 PF09770.4 CDI78678.1 - 0.0006 18.2 32.8 0.0006 18.2 22.8 2.1 2 0 0 2 2 2 1 Topoisomerase II-associated protein PAT1 DUF2514 PF10721.4 CDI78678.1 - 0.0012 18.5 6.9 0.0012 18.5 4.8 4.3 4 0 0 4 4 3 2 Protein of unknown function (DUF2514) Yip1 PF04893.12 CDI78678.1 - 0.0036 16.8 6.1 0.53 9.7 1.7 2.6 2 0 0 2 2 2 2 Yip1 domain TarH PF02203.10 CDI78678.1 - 0.011 15.6 1.9 0.011 15.6 1.3 4.0 2 1 1 3 3 2 0 Tar ligand binding domain homologue Tmemb_9 PF05434.6 CDI78678.1 - 0.24 11.1 0.0 0.24 11.1 0.0 2.4 2 0 0 2 2 1 0 TMEM9 DUF1510 PF07423.6 CDI78678.1 - 0.28 10.5 22.6 1.5 8.1 15.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) DUF2126 PF09899.4 CDI78678.1 - 0.6 8.0 13.3 0.18 9.8 7.3 1.4 2 0 0 2 2 2 0 Putative amidoligase enzyme (DUF2126) Herpes_UL87 PF03043.9 CDI78678.1 - 0.61 8.4 15.1 5.9 5.1 9.3 2.1 2 0 0 2 2 2 0 Herpesvirus UL87 family TT_ORF1 PF02956.9 CDI78678.1 - 0.61 8.4 17.9 0.99 7.7 12.4 1.3 1 0 0 1 1 1 0 TT viral orf 1 eIF-3_zeta PF05091.7 CDI78678.1 - 0.83 8.1 29.8 0.045 12.3 16.7 1.6 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) FLO_LFY PF01698.11 CDI78678.1 - 1.2 7.8 17.7 0.17 10.6 9.6 1.6 2 0 0 2 2 2 0 Floricaula / Leafy protein RNA_pol_Rpb1_2 PF00623.15 CDI78678.1 - 1.3 9.0 9.2 35 4.2 5.9 2.3 2 0 0 2 2 2 0 RNA polymerase Rpb1, domain 2 AUX_IAA PF02309.11 CDI78678.1 - 1.5 8.4 20.7 0.26 10.9 10.7 2.2 2 0 0 2 2 2 0 AUX/IAA family DUF342 PF03961.8 CDI78678.1 - 1.9 6.7 12.1 2.8 6.2 8.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Ycf1 PF05758.7 CDI78678.1 - 3 5.4 20.0 4.6 4.8 13.9 1.2 1 0 0 1 1 1 0 Ycf1 zf-DHHC PF01529.15 CDI78678.1 - 5 6.4 20.6 16 4.8 0.0 3.2 1 1 1 2 2 1 0 DHHC palmitoyltransferase UPF0560 PF10577.4 CDI78678.1 - 6.3 4.9 29.7 16 3.5 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised protein family UPF0560 SAGA-Tad1 PF12767.2 CDI78678.1 - 6.8 6.2 30.1 2.7 7.5 17.7 2.2 2 0 0 2 2 2 0 Transcriptional regulator of RNA polII, SAGA, subunit Acetyltransf_1 PF00583.19 CDI78684.1 - 0.0015 18.4 0.1 0.0034 17.3 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family SP_C-Propep PF08999.5 CDI78684.1 - 0.36 10.3 2.1 4.9 6.6 0.7 2.3 2 0 0 2 2 2 0 Surfactant protein C, N terminal propeptide Peptidase_M41 PF01434.13 CDI78685.1 - 9.4e-47 159.2 0.1 4.3e-46 157.0 0.0 2.1 2 0 0 2 2 2 1 Peptidase family M41 AAA PF00004.24 CDI78685.1 - 3.6e-11 43.3 0.2 0.00021 21.4 0.0 3.2 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.16 CDI78685.1 - 0.0056 15.8 0.1 0.017 14.2 0.1 1.8 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_19 PF13245.1 CDI78685.1 - 0.013 15.2 0.2 0.058 13.1 0.1 2.1 1 0 0 1 1 1 0 Part of AAA domain AAA_5 PF07728.9 CDI78685.1 - 0.028 14.1 0.1 0.064 12.9 0.1 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 CDI78685.1 - 0.04 13.8 0.0 0.04 13.8 0.0 3.4 5 0 0 5 5 5 0 AAA ATPase domain AAA_22 PF13401.1 CDI78685.1 - 0.047 13.8 0.5 0.26 11.4 0.0 2.5 3 0 0 3 3 3 0 AAA domain IstB_IS21 PF01695.12 CDI78685.1 - 0.08 12.3 0.4 0.3 10.5 0.0 2.0 2 0 0 2 2 2 0 IstB-like ATP binding protein Pex14_N PF04695.8 CDI78685.1 - 5.3 7.0 18.6 0.12 12.4 0.9 4.0 4 0 0 4 4 4 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DEAD PF00270.24 CDI78686.1 - 2.2e-31 108.6 0.0 1.3e-22 80.0 0.0 2.2 2 0 0 2 2 2 2 DEAD/DEAH box helicase ResIII PF04851.10 CDI78686.1 - 2.8e-05 24.0 0.0 0.00017 21.4 0.0 2.0 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit NACHT PF05729.7 CDI78686.1 - 0.021 14.4 0.2 0.049 13.3 0.1 1.5 1 0 0 1 1 1 0 NACHT domain AAA_22 PF13401.1 CDI78686.1 - 0.081 13.0 0.0 3.4 7.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain Methyltransf_26 PF13659.1 CDI78692.1 - 4.8e-12 45.9 1.9 1.2e-11 44.7 1.3 1.6 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 CDI78692.1 - 1.7e-10 40.5 0.3 7.7e-05 22.1 0.0 2.1 2 0 0 2 2 2 2 Methyltransferase small domain Methyltrans_SAM PF10672.4 CDI78692.1 - 1.5e-09 37.1 0.1 2.1e-07 30.0 0.0 2.1 2 0 0 2 2 2 2 S-adenosylmethionine-dependent methyltransferase Methyltransf_18 PF12847.2 CDI78692.1 - 7.5e-09 36.1 0.0 3.1e-08 34.1 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.10 CDI78692.1 - 8.2e-06 25.3 0.8 0.032 13.6 0.6 2.1 2 0 0 2 2 2 2 Conserved hypothetical protein 95 Methyltransf_31 PF13847.1 CDI78692.1 - 4.2e-05 23.1 0.0 0.2 11.2 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.7 CDI78692.1 - 0.0033 17.8 0.2 0.89 10.0 0.0 2.5 1 1 1 2 2 2 1 Methyltransferase domain PrmA PF06325.8 CDI78692.1 - 0.004 16.3 0.2 0.0086 15.2 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) N6-adenineMlase PF10237.4 CDI78692.1 - 0.034 13.8 0.0 0.056 13.0 0.0 1.3 1 0 0 1 1 1 0 Probable N6-adenine methyltransferase Methyltransf_24 PF13578.1 CDI78692.1 - 0.042 14.6 0.7 0.15 12.9 0.5 2.0 1 1 0 1 1 1 0 Methyltransferase domain UPF0020 PF01170.13 CDI78692.1 - 0.069 12.7 0.0 8.4 5.9 0.0 2.1 1 1 0 2 2 2 0 Putative RNA methylase family UPF0020 Methyltransf_25 PF13649.1 CDI78692.1 - 0.069 13.5 0.1 0.46 10.8 0.0 2.2 1 1 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.13 CDI78692.1 - 0.17 10.9 0.0 18 4.3 0.0 2.2 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family Activator_LAG-3 PF11498.3 CDI78699.1 - 1.4e-06 27.3 67.6 0.00058 18.7 31.3 3.5 3 0 0 3 3 3 2 Transcriptional activator LAG-3 SR-25 PF10500.4 CDI78699.1 - 0.004 16.6 2.4 0.004 16.6 1.7 3.5 2 1 1 3 3 3 1 Nuclear RNA-splicing-associated protein CAF-1_p150 PF11600.3 CDI78699.1 - 0.39 10.0 41.3 0.057 12.7 19.8 2.5 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal CDC45 PF02724.9 CDI78699.1 - 3.4 5.5 24.8 7.6 4.4 17.2 1.6 1 0 0 1 1 1 0 CDC45-like protein GPCR_chapero_1 PF11904.3 CDI78699.1 - 5.9 5.9 16.8 14 4.6 11.7 1.7 1 0 0 1 1 1 0 GPCR-chaperone CD20 PF04103.10 CDI78739.1 - 3.4 7.5 6.5 16 5.3 0.7 3.3 3 0 0 3 3 3 0 CD20-like family CRM1_C PF08767.6 CDI78770.1 - 6.5e-84 281.5 11.1 5.3e-83 278.5 2.0 3.1 2 1 0 3 3 3 2 CRM1 C terminal Vac14_Fab1_bd PF12755.2 CDI78770.1 - 0.16 12.4 1.7 1.5 9.2 0.0 3.0 3 1 1 4 4 4 0 Vacuolar 14 Fab1-binding region rve PF00665.21 CDI78777.1 - 7.2e-15 55.1 0.0 7.2e-13 48.7 0.0 2.4 2 0 0 2 2 2 1 Integrase core domain Biotin_carb_C PF02785.14 CDI78777.1 - 0.00032 20.6 0.0 0.31 11.0 0.0 2.4 2 0 0 2 2 2 2 Biotin carboxylase C-terminal domain DUF3288 PF11691.3 CDI78777.1 - 0.015 15.0 0.2 11 5.8 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3288) rve_3 PF13683.1 CDI78777.1 - 0.022 14.3 0.1 0.046 13.2 0.1 1.5 1 0 0 1 1 1 0 Integrase core domain DUF849 PF05853.7 CDI78777.1 - 0.14 11.0 0.0 0.41 9.4 0.0 1.7 2 0 0 2 2 2 0 Prokaryotic protein of unknown function (DUF849) HAUS4 PF14735.1 CDI78782.1 - 0.031 13.5 0.6 0.048 12.9 0.4 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 4 Antimicrobial12 PF08107.6 CDI78782.1 - 0.18 11.4 0.2 0.33 10.5 0.2 1.4 1 0 0 1 1 1 0 Pleurocidin family Med15 PF09606.5 CDI78784.1 - 0.0013 17.0 28.5 0.0013 17.0 19.7 1.3 2 0 0 2 2 2 1 ARC105 or Med15 subunit of Mediator complex non-fungal SR-25 PF10500.4 CDI78784.1 - 0.0067 15.9 21.6 0.17 11.2 3.1 2.2 2 0 0 2 2 2 2 Nuclear RNA-splicing-associated protein SOBP PF15279.1 CDI78784.1 - 0.023 15.1 9.9 0.028 14.8 6.9 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein Apt1 PF10351.4 CDI78784.1 - 0.07 11.9 5.9 0.1 11.4 4.1 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain PAT1 PF09770.4 CDI78784.1 - 0.12 10.6 16.5 0.13 10.4 11.4 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 CAF-1_p150 PF11600.3 CDI78784.1 - 0.28 10.5 16.7 1.4 8.2 1.2 2.1 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal FimP PF09766.4 CDI78784.1 - 0.31 10.0 13.8 0.45 9.5 9.6 1.2 1 0 0 1 1 1 0 Fms-interacting protein TFIIA PF03153.8 CDI78784.1 - 0.39 10.5 27.1 0.56 10.0 18.8 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CPSF100_C PF13299.1 CDI78784.1 - 0.8 9.8 6.6 2 8.5 1.8 2.1 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal MDFI PF15316.1 CDI78784.1 - 1.9 8.4 14.6 6.5 6.7 5.5 2.2 2 0 0 2 2 2 0 MyoD family inhibitor Raftlin PF15250.1 CDI78785.1 - 0.0017 16.9 8.2 0.0018 16.8 5.7 1.1 1 0 0 1 1 1 1 Raftlin Ycf1 PF05758.7 CDI78785.1 - 0.0021 15.8 10.5 0.0025 15.6 7.3 1.0 1 0 0 1 1 1 1 Ycf1 Potyvirid-P3 PF13608.1 CDI78785.1 - 0.0035 16.5 9.5 0.0047 16.1 6.6 1.2 1 0 0 1 1 1 1 Protein P3 of Potyviral polyprotein DUF1980 PF09323.5 CDI78785.1 - 0.0061 16.3 6.8 0.0088 15.8 4.7 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1980) Hid1 PF12722.2 CDI78785.1 - 0.017 12.8 10.4 0.018 12.7 7.2 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SID-1_RNA_chan PF13965.1 CDI78785.1 - 0.03 12.5 5.7 0.038 12.1 4.0 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 SAGA-Tad1 PF12767.2 CDI78785.1 - 0.041 13.5 16.0 0.062 12.9 11.1 1.4 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit DUF4446 PF14584.1 CDI78785.1 - 0.17 11.6 8.0 0.39 10.5 5.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) MLANA PF14991.1 CDI78785.1 - 0.2 11.6 1.7 0.38 10.7 0.8 1.9 1 1 0 1 1 1 0 Protein melan-A FAM176 PF14851.1 CDI78785.1 - 0.81 9.3 6.4 1.6 8.3 4.5 1.6 1 0 0 1 1 1 0 FAM176 family PIG-U PF06728.8 CDI78785.1 - 1.8 7.3 10.2 2.1 7.1 6.3 1.6 1 1 0 1 1 1 0 GPI transamidase subunit PIG-U Parvo_coat PF00740.13 CDI78785.1 - 3 6.7 23.2 3.7 6.4 16.1 1.2 1 0 0 1 1 1 0 Parvovirus coat protein VP2 SR-25 PF10500.4 CDI78789.1 - 0.0013 18.2 34.3 0.0029 17.0 23.8 1.6 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Folate_carrier PF01770.13 CDI78789.1 - 0.81 8.1 4.2 1.3 7.4 2.9 1.3 1 0 0 1 1 1 0 Reduced folate carrier Apt1 PF10351.4 CDI78789.1 - 1 8.1 13.7 1.2 7.8 9.5 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain CDC45 PF02724.9 CDI78789.1 - 5.8 4.8 15.7 7.4 4.4 10.9 1.1 1 0 0 1 1 1 0 CDC45-like protein His_Phos_1 PF00300.17 CDI78802.1 - 8.6e-42 142.9 0.0 1.6e-41 142.0 0.0 1.5 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Ribosomal_60s PF00428.14 CDI78802.1 - 0.64 10.4 10.1 1.9 8.9 7.0 1.8 1 0 0 1 1 1 0 60s Acidic ribosomal protein DNA_primase_lrg PF04104.9 CDI78803.1 - 7.4e-05 22.1 0.0 0.0064 15.7 0.0 2.3 1 1 1 2 2 2 2 Eukaryotic and archaeal DNA primase, large subunit Chorion_2 PF03964.10 CDI78803.1 - 0.057 13.9 0.2 0.16 12.5 0.1 1.7 1 0 0 1 1 1 0 Chorion family 2 Ribosomal_60s PF00428.14 CDI78803.1 - 0.25 11.7 9.0 0.32 11.4 3.4 2.4 2 0 0 2 2 2 0 60s Acidic ribosomal protein Caps_assemb_Wzi PF14052.1 CDI78824.1 - 0.084 11.7 8.7 0.093 11.5 6.0 1.0 1 0 0 1 1 1 0 Capsule assembly protein Wzi SR-25 PF10500.4 CDI78824.1 - 0.36 10.2 17.4 0.44 9.9 12.0 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Cas1_AcylT PF07779.7 CDI78824.1 - 0.5 8.7 3.8 0.56 8.6 2.7 1.1 1 0 0 1 1 1 0 10 TM Acyl Transferase domain found in Cas1p OAD_gamma PF04277.8 CDI78824.1 - 1.4 9.3 9.2 0.28 11.5 0.3 2.2 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain CAF-1_p150 PF11600.3 CDI78824.1 - 4.5 6.6 18.5 6.1 6.1 12.8 1.3 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal TFIIF_alpha PF05793.7 CDI78824.1 - 4.5 5.5 15.2 5.2 5.3 10.6 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Ashwin PF15323.1 CDI78824.1 - 9.1 6.2 19.4 11 5.8 13.4 1.1 1 0 0 1 1 1 0 Developmental protein IncA PF04156.9 CDI78835.1 - 5.4e-06 26.1 1.1 1.4e-05 24.8 0.7 1.7 1 0 0 1 1 1 1 IncA protein Tetraspannin PF00335.15 CDI78835.1 - 0.034 13.4 0.2 0.034 13.4 0.1 2.2 2 0 0 2 2 2 0 Tetraspanin family B12D PF06522.6 CDI78835.1 - 0.052 13.2 0.3 0.052 13.2 0.2 3.4 3 1 1 4 4 4 0 NADH-ubiquinone reductase complex 1 MLRQ subunit FA_desaturase PF00487.19 CDI78835.1 - 0.066 12.6 0.3 0.11 11.9 0.2 1.3 1 0 0 1 1 1 0 Fatty acid desaturase Cwf_Cwc_15 PF04889.7 CDI78837.1 - 0.0061 16.2 6.2 0.0069 16.1 4.3 1.0 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein SpoIIIAH PF12685.2 CDI78837.1 - 0.057 12.9 1.8 0.061 12.8 1.2 1.0 1 0 0 1 1 1 0 SpoIIIAH-like protein Alpha-mann_mid PF09261.6 CDI78837.1 - 0.1 12.8 2.3 0.14 12.4 1.6 1.2 1 0 0 1 1 1 0 Alpha mannosidase, middle domain SDP_N PF12278.3 CDI78837.1 - 0.11 12.1 7.4 0.13 11.8 5.2 1.1 1 0 0 1 1 1 0 Sex determination protein N terminal Plasmodium_Vir PF05795.6 CDI78837.1 - 0.15 11.1 2.8 0.17 11.0 2.0 1.0 1 0 0 1 1 1 0 Plasmodium vivax Vir protein DUF755 PF05501.6 CDI78837.1 - 1 9.4 21.9 1.8 8.5 15.2 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF755) Dehydrin PF00257.14 CDI78837.1 - 1.3 9.3 12.6 1.9 8.7 8.7 1.3 1 0 0 1 1 1 0 Dehydrin Mis14 PF08641.7 CDI78837.1 - 1.3 9.0 8.1 2 8.4 5.5 1.5 1 1 0 1 1 1 0 Kinetochore protein Mis14 like TMEM51 PF15345.1 CDI78837.1 - 1.4 8.6 8.6 2.5 7.7 5.9 1.4 1 1 0 1 1 1 0 Transmembrane protein 51 60KD_IMP PF02096.15 CDI78837.1 - 2.6 7.6 6.8 3.4 7.2 4.7 1.1 1 0 0 1 1 1 0 60Kd inner membrane protein DUF4175 PF13779.1 CDI78837.1 - 4.1 4.9 17.3 4.4 4.8 12.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) DUF573 PF04504.9 CDI78837.1 - 8.3 6.7 8.9 4.2 7.7 4.5 1.7 1 1 1 2 2 2 0 Protein of unknown function, DUF573 HemX PF04375.9 CDI78850.1 - 0.0002 20.0 32.2 0.0002 20.0 22.3 4.4 4 0 0 4 4 4 1 HemX SAPS PF04499.10 CDI78850.1 - 0.0024 16.5 46.9 0.018 13.6 1.0 3.1 3 0 0 3 3 3 3 SIT4 phosphatase-associated protein Tudor-knot PF11717.3 CDI78850.1 - 0.0045 16.6 0.1 0.029 14.0 0.1 2.5 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain AAA_11 PF13086.1 CDI78850.1 - 0.01 15.4 48.4 0.053 13.0 0.1 3.8 3 1 0 3 3 3 0 AAA domain HHH_2 PF12826.2 CDI78850.1 - 0.033 14.0 0.0 0.069 13.0 0.0 1.5 1 0 0 1 1 1 0 Helix-hairpin-helix motif Cytochrom_B558a PF05038.8 CDI78850.1 - 0.09 12.4 0.0 0.09 12.4 0.0 2.7 3 1 0 3 3 3 0 Cytochrome Cytochrome b558 alpha-subunit Raftlin PF15250.1 CDI78850.1 - 8.5 4.7 59.5 0.22 10.0 6.8 4.0 4 0 0 4 4 4 0 Raftlin PsbQ PF05757.6 CDI78865.1 - 0.0039 16.6 5.5 0.0039 16.6 3.8 2.1 2 0 0 2 2 2 1 Oxygen evolving enhancer protein 3 (PsbQ) CD20 PF04103.10 CDI78865.1 - 0.0067 16.3 0.3 0.88 9.4 0.0 2.3 2 0 0 2 2 2 1 CD20-like family TFIIA PF03153.8 CDI78865.1 - 0.022 14.6 12.8 0.028 14.3 8.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Shadoo PF14999.1 CDI78865.1 - 0.05 13.4 8.7 0.91 9.3 2.5 2.4 2 0 0 2 2 2 0 Shadow of prion protein, neuroprotective SYS1 PF09801.4 CDI78865.1 - 0.059 13.3 0.2 0.09 12.7 0.1 1.3 1 0 0 1 1 1 0 Integral membrane protein S linking to the trans Golgi network Methyltransf_12 PF08242.7 CDI78865.1 - 0.7 10.4 2.5 0.91 10.0 0.1 2.0 1 1 1 2 2 2 0 Methyltransferase domain TPP_enzyme_C PF02775.16 CDI78865.1 - 1.4 8.5 6.1 0.38 10.3 0.1 2.4 2 1 1 3 3 3 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Phostensin_N PF13916.1 CDI78865.1 - 9.8 6.2 12.0 16 5.5 1.5 2.5 2 0 0 2 2 2 0 PP1-regulatory protein, Phostensin N-terminal POX PF07526.6 CDI78870.1 - 0.01 16.0 9.1 0.01 16.0 6.3 3.4 3 0 0 3 3 3 0 Associated with HOX Herpes_UL87 PF03043.9 CDI78870.1 - 0.2 10.0 1.8 2.6 6.3 0.0 1.8 1 1 1 2 2 2 0 Herpesvirus UL87 family Glyco_transf_15 PF01793.11 CDI78870.1 - 3 6.6 23.4 0.58 9.0 6.3 2.2 2 0 0 2 2 2 0 Glycolipid 2-alpha-mannosyltransferase Herpes_DNAp_acc PF04929.7 CDI78870.1 - 4.5 6.1 18.7 0.35 9.7 7.1 2.6 2 1 0 2 2 2 0 Herpes DNA replication accessory factor Ycf1 PF05758.7 CDI78870.1 - 9.8 3.7 20.4 0.2 9.3 3.3 2.0 2 0 0 2 2 2 0 Ycf1 Sterol-sensing PF12349.3 CDI78883.1 - 2.3e-05 23.8 1.0 2.3e-05 23.8 0.7 2.6 3 1 1 4 4 4 1 Sterol-sensing domain of SREBP cleavage-activation CAF-1_p150 PF11600.3 CDI78883.1 - 0.0048 16.3 10.9 0.0048 16.3 7.5 5.1 5 0 0 5 5 5 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal Patched PF02460.13 CDI78883.1 - 0.0049 14.8 0.1 0.0049 14.8 0.1 2.6 4 0 0 4 4 4 1 Patched family DUF3049 PF11250.3 CDI78883.1 - 0.025 14.3 0.7 0.076 12.7 0.5 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3049) LMBR1 PF04791.11 CDI78883.1 - 0.071 11.6 0.0 6.9 5.1 0.3 3.0 2 1 0 2 2 2 0 LMBR1-like membrane protein VirB3 PF05101.8 CDI78883.1 - 0.23 11.4 0.7 0.91 9.5 0.0 2.3 2 0 0 2 2 2 0 Type IV secretory pathway, VirB3-like protein MSP1_C PF07462.6 CDI78894.1 - 0.2 10.0 11.9 0.22 9.8 8.2 1.0 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus DUF3729 PF12526.3 CDI78894.1 - 0.47 11.8 3.9 0.66 11.3 2.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3729) DUF2910 PF11139.3 CDI78894.1 - 0.92 8.5 13.8 1.4 8.0 9.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2910) SSP160 PF06933.6 CDI78894.1 - 1.3 6.9 24.5 1.5 6.7 17.0 1.0 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Med15 PF09606.5 CDI78894.1 - 2.3 6.3 10.1 2.6 6.1 7.0 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal IncA PF04156.9 CDI78895.1 - 4.2e-09 36.2 6.4 4.2e-09 36.2 4.4 6.7 4 1 2 6 6 6 1 IncA protein DUF4557 PF15101.1 CDI78895.1 - 0.0017 18.2 17.8 0.0017 18.2 12.3 9.6 3 1 6 9 9 9 1 Domain of unknown function (DUF4557) OmpH PF03938.9 CDI78899.1 - 0.0065 16.4 20.8 0.007 16.3 14.4 1.2 1 0 0 1 1 1 1 Outer membrane protein (OmpH-like) DUF4647 PF15504.1 CDI78899.1 - 0.016 14.0 20.5 0.019 13.8 14.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4647) Plexin_cytopl PF08337.7 CDI78899.1 - 0.026 12.8 5.8 0.03 12.6 4.0 1.2 1 0 0 1 1 1 0 Plexin cytoplasmic RasGAP domain Med15 PF09606.5 CDI78899.1 - 0.15 10.2 41.2 0.17 10.0 28.6 1.3 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Daxx PF03344.10 CDI78899.1 - 0.15 10.5 17.8 0.18 10.2 12.3 1.1 1 0 0 1 1 1 0 Daxx Family PAT1 PF09770.4 CDI78899.1 - 0.33 9.1 39.1 0.36 9.0 27.1 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Totivirus_coat PF05518.6 CDI78899.1 - 0.86 7.3 11.4 0.92 7.2 7.9 1.0 1 0 0 1 1 1 0 Totivirus coat protein Asp-B-Hydro_N PF05279.6 CDI78899.1 - 1.1 9.0 7.5 1.3 8.7 5.2 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region DUF4175 PF13779.1 CDI78899.1 - 2.1 5.9 33.1 2.5 5.7 22.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) EssA PF10661.4 CDI78899.1 - 4.4 6.9 12.1 2.7 7.6 5.2 2.1 2 0 0 2 2 2 0 WXG100 protein secretion system (Wss), protein EssA Paramyxo_ncap PF00973.14 CDI78899.1 - 5.1 5.6 16.2 5.7 5.5 11.2 1.2 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Bul1_N PF04425.7 CDI78899.1 - 5.9 5.3 22.8 7.7 4.9 15.8 1.2 1 0 0 1 1 1 0 Bul1 N terminus Utp14 PF04615.8 CDI78899.1 - 6.6 4.7 22.6 8.3 4.4 15.7 1.0 1 0 0 1 1 1 0 Utp14 protein ABC_tran_2 PF12848.2 CDI78899.1 - 7.6 6.4 21.3 8.2 6.3 4.5 2.2 2 0 0 2 2 2 0 ABC transporter Neur_chan_memb PF02932.11 CDI78899.1 - 8 6.2 18.1 10 5.9 12.5 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF4407 PF14362.1 CDI78899.1 - 8.1 5.2 13.4 10 4.9 9.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Apt1 PF10351.4 CDI78900.1 - 0.038 12.8 6.0 0.048 12.5 4.2 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain SpoIIIAH PF12685.2 CDI78900.1 - 0.15 11.5 1.7 0.23 10.9 1.2 1.2 1 0 0 1 1 1 0 SpoIIIAH-like protein Secretin_N_2 PF07655.8 CDI78900.1 - 0.2 12.0 26.7 0.48 10.8 6.2 2.2 2 0 0 2 2 2 0 Secretin N-terminal domain DUF3446 PF11928.3 CDI78900.1 - 0.49 10.6 25.6 1.7 8.9 10.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3446) Cnd1_N PF12922.2 CDI78900.1 - 0.71 9.4 2.7 0.88 9.1 0.0 1.9 1 1 1 2 2 2 0 non-SMC mitotic condensation complex subunit 1, N-term DUF3633 PF12315.3 CDI78900.1 - 0.86 8.8 5.7 4.5 6.5 0.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3633) Pheromone PF08015.6 CDI78900.1 - 4.1 8.2 12.4 0.63 10.8 2.3 2.3 2 0 0 2 2 2 0 Fungal mating-type pheromone BUD22 PF09073.5 CDI78900.1 - 4.5 6.2 7.5 6.6 5.6 5.2 1.2 1 0 0 1 1 1 0 BUD22 SUZ PF12752.2 CDI78900.1 - 7.6 7.1 11.2 1.6 9.3 0.4 2.3 2 0 0 2 2 2 0 SUZ domain PP2C PF00481.16 CDI78902.1 - 2.8e-33 115.4 0.0 7.3e-33 114.0 0.0 1.7 2 0 0 2 2 2 1 Protein phosphatase 2C PP2C_2 PF13672.1 CDI78902.1 - 2.4e-05 23.8 0.0 0.0001 21.8 0.0 2.0 1 1 0 1 1 1 1 Protein phosphatase 2C YjgF_endoribonc PF14588.1 CDI78902.1 - 0.044 13.7 0.0 0.092 12.6 0.0 1.4 1 0 0 1 1 1 0 YjgF/chorismate_mutase-like, putative endoribonuclease CKS PF01111.14 CDI78904.1 - 3.9e-19 68.2 0.0 7.1e-19 67.4 0.0 1.4 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit PAT1 PF09770.4 CDI78904.1 - 1.8 6.6 29.4 2.3 6.3 20.4 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 PIGA PF08288.7 CDI78905.1 - 8e-39 131.9 3.2 1.8e-38 130.7 2.2 1.6 1 0 0 1 1 1 1 PIGA (GPI anchor biosynthesis) Glycos_transf_1 PF00534.15 CDI78905.1 - 3e-12 46.2 0.0 9.5e-06 25.1 0.0 2.4 1 1 1 2 2 2 2 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 CDI78905.1 - 5.1e-09 36.4 0.5 1.8e-07 31.4 0.0 2.6 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_transf_4 PF13439.1 CDI78905.1 - 4.1e-07 29.8 2.5 7.4e-07 29.0 1.8 1.4 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.1 CDI78905.1 - 2.7e-06 27.5 0.1 0.02 15.0 0.0 2.4 1 1 1 2 2 2 2 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 CDI78905.1 - 4.1e-05 23.7 0.0 0.00011 22.4 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_2 PF13477.1 CDI78905.1 - 5.6e-05 22.9 1.0 9.8e-05 22.2 0.7 1.4 1 0 0 1 1 1 1 Glycosyl transferase 4-like DUF1282 PF06930.7 CDI78913.1 - 7.7 6.1 9.3 9 5.9 1.1 3.7 2 1 1 4 4 4 0 Protein of unknown function (DUF1282) DUF1510 PF07423.6 CDI78915.1 - 1.6 8.0 24.0 1.8 7.9 16.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Paf1 PF03985.8 CDI78915.1 - 2.1 6.9 22.3 2.1 7.0 15.4 1.1 1 0 0 1 1 1 0 Paf1 Neur PF00064.13 CDI78915.1 - 2.3 6.2 7.7 2.5 6.0 5.3 1.0 1 0 0 1 1 1 0 Neuraminidase FLO_LFY PF01698.11 CDI78915.1 - 5.7 5.6 19.6 6.1 5.5 13.6 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein BNIP3 PF06553.7 CDI78915.1 - 6.6 6.0 19.2 7 5.9 13.3 1.0 1 0 0 1 1 1 0 BNIP3 NARP1 PF12569.3 CDI78915.1 - 7.4 5.2 23.1 8.1 5.0 16.0 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DDHD PF02862.12 CDI78915.1 - 7.4 6.2 19.8 8.3 6.1 13.7 1.1 1 0 0 1 1 1 0 DDHD domain DUF2561 PF10812.3 CDI78915.1 - 7.5 6.0 6.2 9.4 5.7 4.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2561) Rtf2 PF04641.7 CDI78915.1 - 9.1 5.3 22.4 9.5 5.3 15.5 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger DEAD PF00270.24 CDI78926.1 - 5.6e-09 35.7 3.2 5.6e-09 35.7 2.2 3.5 3 1 1 4 4 4 1 DEAD/DEAH box helicase Ribosomal_60s PF00428.14 CDI78926.1 - 0.00057 20.2 3.6 0.00057 20.2 2.5 9.9 6 3 1 7 7 7 1 60s Acidic ribosomal protein DUF4044 PF13253.1 CDI78926.1 - 0.048 12.8 0.8 0.09 11.9 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4044) Herpes_BLLF1 PF05109.8 CDI78928.1 - 0.16 9.9 13.6 0.2 9.6 9.5 1.1 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) HhH-GPD PF00730.20 CDI78928.1 - 1.1 9.5 14.1 0.4 10.9 3.4 2.6 1 1 0 2 2 2 0 HhH-GPD superfamily base excision DNA repair protein PAT1 PF09770.4 CDI78928.1 - 1.9 6.6 53.5 2.8 6.0 37.1 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 YfhO PF09586.5 CDI78945.1 - 0.00061 17.9 2.7 0.00066 17.8 1.9 1.0 1 0 0 1 1 1 1 Bacterial membrane protein YfhO 7tm_1 PF00001.16 CDI78945.1 - 0.0015 17.7 0.2 0.002 17.3 0.1 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF2339 PF10101.4 CDI78945.1 - 0.0045 15.3 5.5 0.0049 15.2 3.8 1.0 1 0 0 1 1 1 1 Predicted membrane protein (DUF2339) EcsB PF05975.7 CDI78945.1 - 0.0047 15.4 11.2 0.0054 15.2 7.8 1.1 1 0 0 1 1 1 1 Bacterial ABC transporter protein EcsB NicO PF03824.11 CDI78945.1 - 0.0079 15.5 1.1 0.0079 15.5 0.8 2.0 1 1 1 2 2 2 1 High-affinity nickel-transport protein DUF2500 PF10694.4 CDI78945.1 - 0.012 15.5 1.4 1.9 8.5 0.2 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2500) NnrS PF05940.7 CDI78945.1 - 0.029 13.3 4.1 0.033 13.0 2.9 1.1 1 0 0 1 1 1 0 NnrS protein YajC PF02699.10 CDI78945.1 - 0.049 13.3 3.1 0.049 13.3 2.2 3.7 1 1 1 2 2 1 0 Preprotein translocase subunit PigN PF04987.9 CDI78945.1 - 0.057 12.0 5.1 0.063 11.9 3.5 1.2 1 0 0 1 1 1 0 Phosphatidylinositolglycan class N (PIG-N) DUF1510 PF07423.6 CDI78945.1 - 0.058 12.7 6.0 0.33 10.2 0.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) DUF3357 PF11837.3 CDI78945.1 - 0.17 11.7 7.9 0.53 10.1 0.6 2.9 1 1 2 3 3 3 0 Domain of unknown function (DUF3357) DUF4184 PF13803.1 CDI78945.1 - 0.17 11.1 3.8 1.3 8.2 0.3 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4184) Exosortase_EpsH PF09721.5 CDI78945.1 - 0.19 10.9 5.9 0.25 10.5 4.1 1.2 1 0 0 1 1 1 0 Transmembrane exosortase (Exosortase_EpsH) DUF3397 PF11877.3 CDI78945.1 - 0.22 11.5 7.9 0.27 11.2 5.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3397) DUF4131 PF13567.1 CDI78945.1 - 0.22 10.9 8.4 0.65 9.3 4.2 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) Yip1 PF04893.12 CDI78945.1 - 0.23 10.9 3.0 0.39 10.1 2.1 1.4 1 1 0 1 1 1 0 Yip1 domain ABC2_membrane_2 PF12679.2 CDI78945.1 - 0.31 9.8 8.9 0.37 9.5 6.2 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein BatD PF13584.1 CDI78945.1 - 0.4 9.2 5.3 1.3 7.4 0.5 2.1 1 1 0 2 2 2 0 Oxygen tolerance Peptidase_M50B PF13398.1 CDI78945.1 - 0.55 9.5 13.6 0.21 10.9 3.5 2.0 1 1 1 2 2 2 0 Peptidase M50B-like DUF1686 PF07937.6 CDI78945.1 - 0.55 9.8 5.3 0.55 9.8 2.5 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1686) OAD_gamma PF04277.8 CDI78945.1 - 0.57 10.5 5.6 3.9 7.9 0.7 2.6 1 1 2 3 3 3 0 Oxaloacetate decarboxylase, gamma chain 7TM-7TMR_HD PF07698.6 CDI78945.1 - 0.61 9.4 10.4 0.82 9.0 7.2 1.2 1 0 0 1 1 1 0 7TM receptor with intracellular HD hydrolase Wzy_C PF04932.10 CDI78945.1 - 0.67 9.7 5.1 4.2 7.1 3.6 1.9 1 1 0 1 1 1 0 O-Antigen ligase EphA2_TM PF14575.1 CDI78945.1 - 0.76 10.2 11.1 1.1 9.7 0.1 3.4 1 1 1 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain PRA1 PF03208.14 CDI78945.1 - 1.3 8.3 7.1 6.9 5.9 5.0 1.9 1 1 1 2 2 2 0 PRA1 family protein DUF1345 PF07077.6 CDI78945.1 - 1.5 8.2 4.8 6.5 6.2 2.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1345) DUF3522 PF12036.3 CDI78945.1 - 1.6 8.5 7.6 3.8 7.2 4.8 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3522) zf-DHHC PF01529.15 CDI78945.1 - 3.8 6.8 10.8 0.27 10.6 3.5 1.8 1 1 1 2 2 2 0 DHHC palmitoyltransferase DUF475 PF04332.10 CDI78945.1 - 4.1 6.8 6.9 5.8 6.3 4.8 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF475) DUF2615 PF11027.3 CDI78945.1 - 4.4 7.2 13.8 3.8 7.4 3.2 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF2615) CTP_transf_1 PF01148.15 CDI78945.1 - 4.9 6.7 6.7 5.8 6.4 4.6 1.1 1 0 0 1 1 1 0 Cytidylyltransferase family RseC_MucC PF04246.7 CDI78945.1 - 5.8 6.4 8.8 12 5.4 0.2 2.2 1 1 1 2 2 2 0 Positive regulator of sigma(E), RseC/MucC DUF2723 PF11028.3 CDI78945.1 - 5.9 6.3 6.8 8 5.9 4.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2723) TMEM154 PF15102.1 CDI78945.1 - 6.6 6.4 20.9 0.94 9.1 2.8 2.7 1 1 0 2 2 2 0 TMEM154 protein family DUF4079 PF13301.1 CDI78945.1 - 6.9 6.6 10.6 11 5.9 7.3 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF4079) DUF2231 PF09990.4 CDI78945.1 - 7.4 6.9 6.3 2.4 8.5 0.8 2.0 1 1 1 2 2 2 0 Predicted membrane protein (DUF2231) DUF4395 PF14340.1 CDI78945.1 - 7.5 6.6 7.6 0.27 11.3 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4395) Cytochrom_C_asm PF01578.15 CDI78945.1 - 8 5.9 7.2 89 2.5 5.2 1.9 1 1 0 1 1 1 0 Cytochrome C assembly protein DUF2029 PF09594.5 CDI78945.1 - 8.6 5.7 8.4 11 5.4 5.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2029) DUF805 PF05656.9 CDI78945.1 - 8.7 6.1 8.1 3e+02 1.2 5.7 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF805) Uricase PF01014.13 CDI78948.1 - 0.058 13.4 1.5 0.16 12.0 1.0 1.7 1 0 0 1 1 1 0 Uricase PBP1_TM PF14812.1 CDI78948.1 - 0.27 11.5 4.5 0.8 10.0 0.4 2.4 2 1 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Pox_RNA_Pol_19 PF05320.7 CDI78948.1 - 0.86 9.3 6.7 0.67 9.6 0.8 2.4 2 0 0 2 2 2 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit PH_BEACH PF14844.1 CDI78948.1 - 1.3 8.9 6.6 0.2 11.4 1.1 2.2 1 1 1 2 2 2 0 PH domain associated with Beige/BEACH SprA-related PF12118.3 CDI78948.1 - 2.2 7.5 56.2 3 7.0 21.3 2.2 2 0 0 2 2 2 0 SprA-related family SprA-related PF12118.3 CDI78949.1 - 2.1e-05 23.9 39.8 2.1e-05 23.9 27.6 5.1 3 2 0 3 3 3 1 SprA-related family DUF755 PF05501.6 CDI78949.1 - 0.0059 16.6 2.0 0.0059 16.6 1.4 8.8 5 4 1 6 6 6 1 Domain of unknown function (DUF755) Ribosomal_60s PF00428.14 CDI78949.1 - 0.019 15.3 6.5 0.019 15.3 4.5 6.9 5 3 0 5 5 5 0 60s Acidic ribosomal protein 2HCT PF03390.10 CDI78954.1 - 0.016 13.6 4.1 0.02 13.3 2.8 1.1 1 0 0 1 1 1 0 2-hydroxycarboxylate transporter family DUF4386 PF14329.1 CDI78954.1 - 0.022 14.2 3.9 0.028 13.9 2.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4386) DUF2215 PF10225.4 CDI78954.1 - 0.086 12.2 9.8 0.1 12.0 6.8 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) Med15 PF09606.5 CDI78954.1 - 0.11 10.6 56.6 0.13 10.4 39.2 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Nop53 PF07767.6 CDI78954.1 - 0.13 11.2 33.6 0.14 11.1 23.3 1.0 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) YbgS PF13985.1 CDI78954.1 - 0.26 11.2 16.0 0.31 10.9 11.1 1.1 1 0 0 1 1 1 0 YbgS-like protein Tetraspannin PF00335.15 CDI78954.1 - 0.27 10.4 5.2 0.31 10.2 3.6 1.1 1 0 0 1 1 1 0 Tetraspanin family FHIPEP PF00771.15 CDI78954.1 - 0.43 8.8 13.1 0.5 8.6 9.1 1.2 1 0 0 1 1 1 0 FHIPEP family Lgl_C PF08596.5 CDI78954.1 - 0.54 8.6 7.3 0.67 8.3 5.0 1.1 1 0 0 1 1 1 0 Lethal giant larvae(Lgl) like, C-terminal MIP-T3 PF10243.4 CDI78954.1 - 0.69 8.3 33.3 0.81 8.0 23.1 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Bac_luciferase PF00296.15 CDI78954.1 - 0.98 8.4 14.6 1.2 8.2 10.1 1.3 1 1 0 1 1 1 0 Luciferase-like monooxygenase Rtf2 PF04641.7 CDI78954.1 - 1.2 8.3 24.2 1.3 8.1 16.7 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger CCD PF07860.6 CDI78954.1 - 1.2 8.6 3.8 1.7 8.1 2.5 1.4 1 1 0 1 1 1 0 WisP family C-Terminal Region TATR PF03430.8 CDI78954.1 - 1.4 7.4 15.6 1.6 7.2 10.8 1.1 1 0 0 1 1 1 0 Trans-activating transcriptional regulator DUF1754 PF08555.5 CDI78954.1 - 2.2 8.9 25.9 3.7 8.2 18.0 1.4 1 1 0 1 1 1 0 Eukaryotic family of unknown function (DUF1754) FAM60A PF15396.1 CDI78954.1 - 2.5 7.7 20.4 2.7 7.6 14.1 1.1 1 0 0 1 1 1 0 Protein Family FAM60A Folate_carrier PF01770.13 CDI78954.1 - 2.8 6.3 9.9 3.6 6.0 6.9 1.4 1 0 0 1 1 1 0 Reduced folate carrier Anoctamin PF04547.7 CDI78954.1 - 2.9 6.4 8.5 3 6.4 5.9 1.3 1 0 0 1 1 1 0 Calcium-activated chloride channel FadA PF09403.5 CDI78954.1 - 3.8 7.5 19.6 5.2 7.0 13.6 1.3 1 0 0 1 1 1 0 Adhesion protein FadA SID-1_RNA_chan PF13965.1 CDI78954.1 - 5.5 5.0 11.0 5.5 5.0 7.6 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 RNA_pol_Rpb1_5 PF04998.12 CDI78954.1 - 6.5 5.9 12.6 6.9 5.8 8.7 1.1 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 LMBR1 PF04791.11 CDI78954.1 - 8.9 4.7 11.1 9.7 4.6 7.7 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein CDC45 PF02724.9 CDI78954.1 - 9.4 4.1 19.5 10 4.0 13.5 1.1 1 0 0 1 1 1 0 CDC45-like protein RRM_1 PF00076.17 CDI78984.1 - 1.4e-29 101.4 0.1 1.4e-16 59.8 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CDI78984.1 - 1.6e-23 82.4 0.0 3e-12 46.3 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CDI78984.1 - 5.8e-05 22.8 0.0 0.00046 19.9 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) tRNA-synt_2c PF01411.14 CDI78985.1 - 6.6e-194 645.2 0.0 8.2e-194 644.9 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.9 CDI78985.1 - 5.7e-16 58.1 0.1 1.2e-15 57.0 0.0 1.6 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.14 CDI78985.1 - 0.00044 19.8 0.9 0.0018 17.9 0.1 2.4 2 0 0 2 2 2 1 DHHA1 domain DUF3381 PF11861.3 CDI78993.1 - 0.0041 16.6 12.7 0.036 13.5 0.1 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3381) DUF4126 PF13548.1 CDI78993.1 - 0.41 10.0 6.7 0.7 9.3 4.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4126) DUF912 PF06024.7 CDI78993.1 - 0.66 10.0 8.8 0.77 9.8 1.1 2.5 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF1917 PF08939.5 CDI78993.1 - 0.77 9.4 10.2 1.7 8.3 7.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1917) DUF808 PF05661.7 CDI78993.1 - 1.9 7.2 6.0 0.45 9.3 0.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF808) Bacteriocin_IIc PF10439.4 CDI78993.1 - 2.3 8.4 13.9 0.38 10.8 6.8 1.8 2 0 0 2 2 2 0 Bacteriocin class II with double-glycine leader peptide RED_N PF07808.8 CDI78993.1 - 3.5 6.7 26.2 0.54 9.4 8.5 2.2 2 0 0 2 2 2 0 RED-like protein N-terminal region Hid1 PF12722.2 CDI78993.1 - 4.1 4.9 13.7 6 4.4 9.5 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF3408 PF11888.3 CDI78993.1 - 4.3 7.2 15.6 1.9 8.4 3.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3408) PROL5-SMR PF15621.1 CDI78993.1 - 4.4 7.7 9.7 8.1 6.9 6.7 1.4 1 0 0 1 1 1 0 Proline-rich submaxillary gland androgen-regulated family Peroxin-13_N PF04088.8 CDI78993.1 - 4.7 7.1 15.0 0.1 12.5 2.8 2.3 1 1 1 2 2 2 0 Peroxin 13, N-terminal region DUF2203 PF09969.4 CDI78993.1 - 5.5 7.2 17.9 0.37 11.0 5.8 2.5 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) Herpes_DNAp_acc PF04929.7 CDI78993.1 - 6 5.7 16.8 9.3 5.0 11.6 1.3 1 0 0 1 1 1 0 Herpes DNA replication accessory factor SR-25 PF10500.4 CDI78998.1 - 0.0063 16.0 25.0 0.0063 16.0 17.3 6.0 2 2 2 4 4 4 2 Nuclear RNA-splicing-associated protein Rhodanese PF00581.15 CDI79002.1 - 1.5e-08 34.9 2.6 5.3e-06 26.7 0.0 4.0 3 2 1 4 4 4 1 Rhodanese-like domain DUF755 PF05501.6 CDI79002.1 - 0.012 15.6 16.8 0.012 15.6 11.6 6.9 6 1 1 7 7 7 0 Domain of unknown function (DUF755) CAF-1_p150 PF11600.3 CDI79005.1 - 0.00096 18.5 20.9 0.00096 18.5 14.5 2.1 2 0 0 2 2 2 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal TctA PF01970.11 CDI79005.1 - 0.016 13.6 2.4 0.02 13.3 1.6 1.3 1 0 0 1 1 1 0 Tripartite tricarboxylate transporter TctA family RAP1 PF07218.6 CDI79005.1 - 0.81 7.7 4.0 0.88 7.5 2.8 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) BCCT PF02028.12 CDI79005.1 - 4.7 5.3 8.8 2.2 6.4 4.7 1.4 1 1 0 1 1 1 0 BCCT family transporter ExoD PF06055.7 CDI79005.1 - 4.9 6.2 6.7 0.19 10.8 0.1 1.9 2 0 0 2 2 2 0 Exopolysaccharide synthesis, ExoD LMBR1 PF04791.11 CDI79031.1 - 0.004 15.8 6.3 0.03 12.9 0.0 3.2 1 1 1 2 2 2 1 LMBR1-like membrane protein CDV3 PF15359.1 CDI79043.1 - 0.16 12.0 8.7 1 9.4 1.6 2.8 2 0 0 2 2 2 0 Carnitine deficiency-associated protein 3 Pkinase PF00069.20 CDI79061.1 - 1.8e-61 207.6 0.0 2e-61 207.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDI79061.1 - 4.9e-31 107.7 0.0 5.9e-31 107.4 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CDI79061.1 - 1.4e-07 30.7 0.0 2.1e-07 30.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 CDI79061.1 - 0.013 14.9 0.0 0.023 14.0 0.0 1.3 1 0 0 1 1 1 0 RIO1 family APH PF01636.18 CDI79061.1 - 0.051 13.3 0.0 0.15 11.7 0.0 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 CDI79061.1 - 0.08 12.2 0.0 0.16 11.3 0.0 1.5 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Med15 PF09606.5 CDI79070.1 - 0.044 12.0 36.0 0.049 11.8 25.0 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal MOSP_N PF02707.11 CDI79070.1 - 0.15 11.6 1.6 0.27 10.7 1.1 1.4 1 0 0 1 1 1 0 Major Outer Sheath Protein N-terminal region EB1_binding PF05937.6 CDI79070.1 - 0.96 9.7 10.4 1.3 9.4 6.7 1.5 1 1 0 1 1 1 0 EB-1 Binding Domain Utp14 PF04615.8 CDI79093.1 - 0.0024 16.1 25.1 0.0026 15.9 17.4 1.1 1 0 0 1 1 1 1 Utp14 protein PAT1 PF09770.4 CDI79093.1 - 0.027 12.7 54.4 0.034 12.4 37.7 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 HlyD_2 PF12700.2 CDI79093.1 - 0.048 12.8 21.0 0.062 12.4 14.6 1.2 1 0 0 1 1 1 0 HlyD family secretion protein CDC45 PF02724.9 CDI79093.1 - 0.048 11.6 20.9 0.063 11.2 14.5 1.1 1 0 0 1 1 1 0 CDC45-like protein Spore_coat_CotO PF14153.1 CDI79093.1 - 0.055 12.9 36.9 0.12 11.7 25.6 1.6 1 0 0 1 1 1 0 Spore coat protein CotO Cwf_Cwc_15 PF04889.7 CDI79093.1 - 0.082 12.6 27.2 0.12 12.0 18.9 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Ycf1 PF05758.7 CDI79093.1 - 0.085 10.5 21.8 0.1 10.2 15.1 1.1 1 0 0 1 1 1 0 Ycf1 Tim54 PF11711.3 CDI79093.1 - 0.13 10.8 13.2 0.22 10.0 9.2 1.4 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 GAGA_bind PF06217.7 CDI79093.1 - 0.15 11.9 21.1 0.21 11.5 14.6 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family LMBR1 PF04791.11 CDI79093.1 - 0.22 10.0 9.8 0.28 9.7 6.8 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Cellulose_synt PF03552.9 CDI79093.1 - 0.25 9.6 8.9 0.31 9.3 6.2 1.1 1 0 0 1 1 1 0 Cellulose synthase Raftlin PF15250.1 CDI79093.1 - 0.43 9.0 20.0 0.59 8.6 13.8 1.3 1 0 0 1 1 1 0 Raftlin PPP4R2 PF09184.6 CDI79093.1 - 0.71 9.3 23.5 1 8.8 16.3 1.3 1 0 0 1 1 1 0 PPP4R2 Pox_Ag35 PF03286.9 CDI79093.1 - 0.76 9.2 21.2 1.5 8.2 14.7 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DDRGK PF09756.4 CDI79093.1 - 0.94 8.8 35.0 1.5 8.1 24.3 1.3 1 0 0 1 1 1 0 DDRGK domain SAPS PF04499.10 CDI79093.1 - 0.99 7.9 20.2 1.4 7.5 14.0 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Paramyxo_ncap PF00973.14 CDI79093.1 - 1 7.9 19.5 1.4 7.5 13.5 1.4 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Hid1 PF12722.2 CDI79093.1 - 1.1 6.8 28.1 1.5 6.3 19.5 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein PRP1_N PF06424.7 CDI79093.1 - 2 8.7 27.1 4.2 7.7 18.8 1.5 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal DUF4647 PF15504.1 CDI79093.1 - 2.6 6.7 28.3 3.6 6.3 19.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4647) Cyto_ox_2 PF02322.10 CDI79093.1 - 2.8 7.0 15.8 0.25 10.4 7.3 1.7 2 0 0 2 2 2 0 Cytochrome oxidase subunit II HCO3_cotransp PF00955.16 CDI79093.1 - 3 6.3 4.8 4.1 5.9 3.3 1.3 1 0 0 1 1 1 0 HCO3- transporter family RAP1 PF07218.6 CDI79093.1 - 3.2 5.7 11.8 0.52 8.3 5.9 1.3 1 1 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) V_ATPase_I PF01496.14 CDI79093.1 - 4 5.1 12.8 5 4.8 8.8 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family PCEMA1 PF07418.6 CDI79093.1 - 4.5 6.5 17.6 6 6.1 12.2 1.2 1 0 0 1 1 1 0 Acidic phosphoprotein precursor PCEMA1 BTV_NS2 PF04514.7 CDI79093.1 - 6.8 5.4 20.7 9.8 4.9 14.4 1.2 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Parvo_coat PF00740.13 CDI79093.1 - 6.9 5.4 29.4 9 5.1 20.4 1.2 1 0 0 1 1 1 0 Parvovirus coat protein VP2 Otopetrin PF03189.8 CDI79093.1 - 9.9 5.0 9.3 14 4.5 6.4 1.4 1 0 0 1 1 1 0 Otopetrin DUF1180 PF06679.7 CDI79106.1 - 6.5 6.6 12.8 0.22 11.4 3.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) DUF2967 PF11179.3 CDI79120.1 - 0.0015 18.0 10.6 0.0025 17.3 7.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2967) Corona_nucleoca PF00937.13 CDI79120.1 - 0.0025 16.8 6.5 0.0036 16.3 4.5 1.1 1 0 0 1 1 1 1 Coronavirus nucleocapsid protein Period_C PF12114.3 CDI79120.1 - 0.056 13.0 11.1 0.55 9.8 4.1 2.9 3 0 0 3 3 3 0 Period protein 2/3C-terminal region Chorion_2 PF03964.10 CDI79120.1 - 0.094 13.2 7.4 3.2 8.3 0.1 2.4 2 0 0 2 2 2 0 Chorion family 2 CDK2AP PF09806.4 CDI79120.1 - 0.22 11.7 7.4 6.7 6.9 0.0 2.2 2 0 0 2 2 2 0 Cyclin-dependent kinase 2-associated protein DUF3446 PF11928.3 CDI79120.1 - 0.35 11.0 13.2 0.23 11.6 5.8 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3446) NDT80_PhoG PF05224.7 CDI79164.1 - 0.041 13.8 2.2 0.074 13.0 1.5 1.4 1 0 0 1 1 1 0 NDT80 / PhoG like DNA-binding family LPP PF04728.8 CDI79166.1 - 0.0035 17.0 6.3 0.071 12.9 0.1 4.1 5 0 0 5 5 5 2 Lipoprotein leucine-zipper NPV_P10 PF05531.7 CDI79166.1 - 0.026 14.7 24.3 8.6 6.6 0.2 7.2 6 2 2 8 8 8 0 Nucleopolyhedrovirus P10 protein Reo_sigmaC PF04582.7 CDI79166.1 - 0.78 8.8 27.6 3.3 6.7 0.7 5.1 3 1 1 5 5 5 0 Reovirus sigma C capsid protein GAS PF13851.1 CDI79166.1 - 0.92 8.6 71.4 0.0095 15.1 7.3 4.5 4 0 0 4 4 4 0 Growth-arrest specific micro-tubule binding PUA PF01472.15 CDI79169.1 - 2.2e-15 56.1 0.0 3.4e-15 55.5 0.0 1.3 1 0 0 1 1 1 1 PUA domain Activator_LAG-3 PF11498.3 CDI79178.1 - 0.0021 16.8 32.9 0.0021 16.8 22.8 3.6 2 1 1 3 3 3 1 Transcriptional activator LAG-3 Mucin PF01456.12 CDI79188.1 - 0.0058 16.4 3.1 0.0058 16.4 2.2 2.3 2 0 0 2 2 2 1 Mucin-like glycoprotein Activator_LAG-3 PF11498.3 CDI79188.1 - 0.0072 15.1 12.7 0.013 14.2 8.8 1.4 1 0 0 1 1 1 1 Transcriptional activator LAG-3 PAT1 PF09770.4 CDI79188.1 - 2.2 6.3 11.5 2.6 6.2 8.0 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 AAA_23 PF13476.1 CDI79195.1 - 0.018 15.3 22.0 0.022 15.0 15.2 1.2 1 0 0 1 1 1 0 AAA domain V_ATPase_I PF01496.14 CDI79195.1 - 5.3 4.7 14.2 7.9 4.1 9.8 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4446 PF14584.1 CDI79195.1 - 8.4 6.2 11.0 20 4.9 7.6 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) Daxx PF03344.10 CDI79220.1 - 0.00068 18.2 29.9 0.0008 18.0 20.7 1.0 1 0 0 1 1 1 1 Daxx Family Nop14 PF04147.7 CDI79220.1 - 0.00099 17.1 23.0 0.0012 16.8 15.9 1.1 1 0 0 1 1 1 1 Nop14-like family DUF2890 PF11081.3 CDI79220.1 - 0.064 13.3 28.0 0.076 13.0 19.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) SDA1 PF05285.7 CDI79220.1 - 0.088 12.0 26.8 0.13 11.5 18.5 1.2 1 0 0 1 1 1 0 SDA1 Med15 PF09606.5 CDI79220.1 - 0.1 10.7 29.5 0.087 11.0 20.5 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF2946 PF11162.3 CDI79220.1 - 0.18 12.0 1.5 0.24 11.6 1.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2946) DUF912 PF06024.7 CDI79220.1 - 0.32 11.0 9.8 4.3 7.4 3.7 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) CENP-T PF15511.1 CDI79220.1 - 1.2 8.3 25.4 1.5 8.0 17.6 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Pap_E4 PF02711.9 CDI79220.1 - 1.7 9.4 20.5 2.8 8.8 7.4 2.1 2 0 0 2 2 2 0 E4 protein FYDLN_acid PF09538.5 CDI79220.1 - 1.7 9.2 23.6 2.8 8.5 9.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) LIM_bind PF01803.11 CDI79220.1 - 2.8 6.9 13.5 4.5 6.3 9.3 1.3 1 0 0 1 1 1 0 LIM-domain binding protein eRF1_3 PF03465.10 CDI79229.1 - 6.4e-05 23.1 1.1 6.4e-05 23.1 0.7 1.6 1 1 1 2 2 2 1 eRF1 domain 3 DUF2930 PF11152.3 CDI79229.1 - 0.092 11.8 0.4 0.12 11.5 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2930) APC_CDC26 PF10471.4 CDI79229.1 - 0.8 10.4 32.2 2.1 9.1 4.8 2.1 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit 1 DUF4643 PF15485.1 CDI79229.1 - 0.92 8.9 6.8 1.4 8.3 4.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4643) OAD_gamma PF04277.8 CDI79229.1 - 0.95 9.8 4.3 0.64 10.4 1.4 1.8 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain GAGA_bind PF06217.7 CDI79229.1 - 1.9 8.3 10.4 2.3 8.1 7.2 1.0 1 0 0 1 1 1 0 GAGA binding protein-like family Phostensin_N PF13916.1 CDI79229.1 - 3 7.9 11.9 2.4 8.2 1.5 2.4 2 0 0 2 2 2 0 PP1-regulatory protein, Phostensin N-terminal RepL PF05732.6 CDI79229.1 - 5 6.3 9.4 0.25 10.5 1.9 1.9 2 0 0 2 2 2 0 Firmicute plasmid replication protein (RepL) CytochromB561_N PF09786.4 CDI79229.1 - 5.5 5.3 10.3 6.3 5.1 7.2 1.0 1 0 0 1 1 1 0 Cytochrome B561, N terminal BTV_NS2 PF04514.7 CDI79229.1 - 5.6 5.7 11.5 6.8 5.4 7.9 1.2 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 DUF1764 PF08576.5 CDI79229.1 - 6.8 7.5 13.5 5.5 7.8 0.7 2.1 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF1764) SelP_N PF04592.9 CDI79232.1 - 0.054 12.8 23.3 0.063 12.6 16.1 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region DUF1510 PF07423.6 CDI79232.1 - 0.39 10.0 34.2 0.41 9.9 23.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Pox_Ag35 PF03286.9 CDI79232.1 - 0.64 9.5 22.4 0.72 9.3 15.5 1.0 1 0 0 1 1 1 0 Pox virus Ag35 surface protein HCO3_cotransp PF00955.16 CDI79232.1 - 1.9 7.0 11.3 2.2 6.8 7.8 1.0 1 0 0 1 1 1 0 HCO3- transporter family DUF2201_N PF13203.1 CDI79232.1 - 3 6.9 35.1 3.1 6.8 24.4 1.0 1 0 0 1 1 1 0 Putative metallopeptidase domain Raftlin PF15250.1 CDI79232.1 - 4.4 5.7 30.4 4.6 5.6 21.0 1.0 1 0 0 1 1 1 0 Raftlin Zip PF02535.17 CDI79232.1 - 6.6 5.6 17.2 8.9 5.2 11.9 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter CDC45 PF02724.9 CDI79232.1 - 6.9 4.5 33.1 7.1 4.5 22.9 1.0 1 0 0 1 1 1 0 CDC45-like protein RR_TM4-6 PF06459.7 CDI79232.1 - 7.7 6.3 31.6 11 5.8 21.9 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF4045 PF13254.1 CDI79232.1 - 7.8 5.6 29.9 8.1 5.6 20.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Rtf2 PF04641.7 CDI79232.1 - 9.8 5.2 32.2 11 5.1 22.3 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger LAT PF15234.1 CDI79234.1 - 0.017 14.5 0.1 0.018 14.5 0.1 1.0 1 0 0 1 1 1 0 Linker for activation of T-cells DUF4175 PF13779.1 CDI79234.1 - 0.02 12.6 10.8 0.018 12.7 7.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) dsDNA_bind PF01984.15 CDI79234.1 - 0.031 14.2 12.0 0.031 14.2 8.3 1.2 1 0 0 1 1 1 0 Double-stranded DNA-binding domain Flavodoxin_NdrI PF07972.6 CDI79234.1 - 0.044 13.6 0.6 0.044 13.6 0.4 1.1 1 0 0 1 1 1 0 NrdI Flavodoxin like Afi1 PF07792.7 CDI79234.1 - 0.066 13.2 2.6 0.068 13.1 1.8 1.0 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Pex16 PF08610.5 CDI79234.1 - 0.13 11.1 5.0 0.14 11.1 3.5 1.0 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) DUF2722 PF10846.3 CDI79234.1 - 0.16 10.9 6.5 0.15 11.0 4.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Activator_LAG-3 PF11498.3 CDI79234.1 - 0.18 10.5 19.4 0.16 10.6 13.4 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Pex14_N PF04695.8 CDI79234.1 - 0.23 11.4 7.0 0.25 11.4 4.8 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF912 PF06024.7 CDI79234.1 - 0.46 10.5 1.9 0.52 10.3 1.3 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) RAB3GAP2_N PF14655.1 CDI79234.1 - 0.54 9.2 6.4 0.58 9.0 4.5 1.0 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus OATP PF03137.15 CDI79234.1 - 0.56 8.1 3.3 0.56 8.1 2.3 1.0 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Spt20 PF12090.3 CDI79234.1 - 0.67 9.2 7.7 0.66 9.2 5.3 1.1 1 0 0 1 1 1 0 Spt20 family BRF1 PF07741.8 CDI79234.1 - 1.1 9.4 7.3 1.3 9.3 5.0 1.1 1 0 0 1 1 1 0 Brf1-like TBP-binding domain Dpy19 PF10034.4 CDI79234.1 - 1.2 7.1 3.5 1.3 7.1 2.4 1.0 1 0 0 1 1 1 0 Q-cell neuroblast polarisation Med15 PF09606.5 CDI79234.1 - 1.6 6.8 24.4 1.6 6.8 16.9 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF3306 PF11748.3 CDI79234.1 - 1.6 9.4 9.6 1.9 9.1 6.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3306) TraV PF09676.5 CDI79234.1 - 1.7 9.3 8.0 1.8 9.3 5.6 1.0 1 0 0 1 1 1 0 Type IV conjugative transfer system lipoprotein (TraV) Suf PF05843.9 CDI79234.1 - 2.1 8.0 8.5 1.9 8.1 5.9 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) UPF0560 PF10577.4 CDI79234.1 - 2.4 6.3 8.0 2 6.5 5.5 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 DUF4557 PF15101.1 CDI79234.1 - 2.5 7.8 9.3 2.3 8.0 6.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) PAT1 PF09770.4 CDI79234.1 - 4.3 5.4 14.7 3.8 5.6 10.2 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 CAF-1_p150 PF11600.3 CDI79251.1 - 0.0046 16.3 22.7 0.0046 16.3 15.7 10.8 8 2 2 10 10 10 2 Chromatin assembly factor 1 complex p150 subunit, N-terminal TraT PF05818.7 CDI79251.1 - 0.061 12.7 0.1 0.061 12.7 0.1 10.1 9 3 2 11 11 11 0 Enterobacterial TraT complement resistance protein DUF137 PF02006.11 CDI79251.1 - 4.8 6.5 10.4 0.034 13.5 0.4 2.5 2 0 0 2 2 2 0 Protein of unknown function DUF137 MIP-T3 PF10243.4 CDI79252.1 - 0.01 14.3 36.7 0.014 13.8 25.4 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Daxx PF03344.10 CDI79252.1 - 0.42 9.0 33.5 0.47 8.8 23.2 1.1 1 0 0 1 1 1 0 Daxx Family Utp14 PF04615.8 CDI79252.1 - 0.89 7.6 35.3 1.2 7.2 24.4 1.1 1 0 0 1 1 1 0 Utp14 protein DDRGK PF09756.4 CDI79252.1 - 6.1 6.2 22.7 9.9 5.5 15.7 1.3 1 0 0 1 1 1 0 DDRGK domain Syja_N PF02383.13 CDI79260.1 - 3.3e-14 52.3 12.1 1.4e-10 40.4 7.7 6.6 6 2 0 6 6 6 2 SacI homology domain SR-25 PF10500.4 CDI79260.1 - 0.00061 19.3 4.5 0.00061 19.3 3.1 12.4 10 3 2 13 13 13 2 Nuclear RNA-splicing-associated protein IncA PF04156.9 CDI79260.1 - 0.0056 16.3 8.4 0.0056 16.3 5.9 9.3 7 3 1 8 8 8 2 IncA protein DUF3801 PF12687.2 CDI79260.1 - 0.016 14.7 0.2 0.016 14.7 0.2 8.0 8 0 0 8 8 8 0 Protein of unknown function (DUF3801) EphA2_TM PF14575.1 CDI79260.1 - 0.033 14.5 0.6 0.033 14.5 0.4 8.0 8 0 0 8 8 8 0 Ephrin type-A receptor 2 transmembrane domain Abhydrolase_5 PF12695.2 CDI79273.1 - 0.014 15.1 0.1 0.025 14.3 0.1 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family MutS_V PF00488.16 CDI79314.1 - 1.4e-10 40.9 0.3 0.00099 18.5 0.0 3.2 3 0 0 3 3 3 2 MutS domain V Sporozoite_P67 PF05642.6 CDI79314.1 - 9e-08 30.4 10.6 9e-08 30.4 7.3 3.4 3 1 0 3 3 3 1 Sporozoite P67 surface antigen SR-25 PF10500.4 CDI79314.1 - 0.0055 16.1 11.0 0.0055 16.1 7.7 6.2 3 2 2 6 6 6 1 Nuclear RNA-splicing-associated protein Mucin PF01456.12 CDI79314.1 - 0.0089 15.8 4.0 0.0089 15.8 2.8 5.1 4 1 1 5 5 5 1 Mucin-like glycoprotein Ribosomal_60s PF00428.14 CDI79314.1 - 0.014 15.7 6.9 0.014 15.7 4.8 7.1 5 1 0 5 5 5 0 60s Acidic ribosomal protein Herpes_UL87 PF03043.9 CDI79324.1 - 2.6e-05 22.8 10.1 2.6e-05 22.8 7.0 3.5 2 1 0 3 3 3 2 Herpesvirus UL87 family SOBP PF15279.1 CDI79324.1 - 0.00019 21.9 12.1 0.00019 21.9 8.4 4.7 4 1 1 5 5 5 2 Sine oculis-binding protein SIS PF01380.17 CDI79326.1 - 3.6e-33 113.9 0.3 3.4e-18 65.5 0.0 2.9 3 0 0 3 3 3 2 SIS domain GATase_6 PF13522.1 CDI79326.1 - 1e-21 77.3 0.0 2e-21 76.3 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.1 CDI79326.1 - 3.2e-18 65.6 0.0 6.6e-18 64.6 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_2 PF00310.16 CDI79326.1 - 6.9e-14 51.3 0.4 1.2e-11 43.9 0.0 2.4 1 1 1 2 2 2 2 Glutamine amidotransferases class-II GATase_4 PF13230.1 CDI79326.1 - 5.1e-07 28.6 0.2 9.9e-07 27.7 0.1 1.4 1 0 0 1 1 1 1 Glutamine amidotransferases class-II LRR_4 PF12799.2 CDI79329.1 - 1.3e-16 59.8 13.3 3.3e-07 29.7 0.2 3.6 3 0 0 3 3 3 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 CDI79329.1 - 1.7e-09 36.4 19.4 0.36 11.0 0.4 6.8 5 1 1 6 6 6 5 Leucine Rich Repeat LRR_7 PF13504.1 CDI79329.1 - 4.9e-06 25.8 16.7 0.77 10.2 0.1 6.6 6 0 0 6 6 6 3 Leucine rich repeat LRR_8 PF13855.1 CDI79329.1 - 6e-06 25.9 14.3 0.00037 20.1 1.1 3.5 1 1 3 4 4 4 4 Leucine rich repeat LRR_6 PF13516.1 CDI79329.1 - 0.00011 21.8 17.8 5 7.4 0.0 6.6 6 0 0 6 6 6 3 Leucine Rich repeat LRR_9 PF14580.1 CDI79329.1 - 0.0019 17.7 1.6 0.0066 16.0 0.6 2.0 1 1 0 2 2 2 1 Leucine-rich repeat DUF3357 PF11837.3 CDI79346.1 - 0.0024 17.7 0.4 0.0024 17.7 0.3 2.4 1 1 1 2 2 1 1 Domain of unknown function (DUF3357) DUF1510 PF07423.6 CDI79346.1 - 0.011 15.0 26.6 0.016 14.6 18.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Herpes_DNAp_acc PF04929.7 CDI79346.1 - 0.35 9.7 22.2 0.41 9.5 15.4 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor GAGA_bind PF06217.7 CDI79346.1 - 0.71 9.7 25.9 0.78 9.6 18.0 1.0 1 0 0 1 1 1 0 GAGA binding protein-like family SAPS PF04499.10 CDI79346.1 - 2 6.9 25.4 2.4 6.6 17.6 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein TFIIA PF03153.8 CDI79346.1 - 2.1 8.1 44.3 2.9 7.7 30.7 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit K_trans PF02705.11 CDI79346.1 - 2.5 6.3 8.1 3 6.0 5.6 1.1 1 0 0 1 1 1 0 K+ potassium transporter Hid1 PF12722.2 CDI79346.1 - 2.6 5.6 31.7 2.9 5.4 22.0 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Ycf1 PF05758.7 CDI79346.1 - 2.8 5.5 29.2 3.2 5.3 20.3 1.1 1 0 0 1 1 1 0 Ycf1 eIF-3_zeta PF05091.7 CDI79346.1 - 3.5 6.1 32.0 5 5.6 22.2 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Dicty_REP PF05086.7 CDI79346.1 - 3.7 5.1 21.5 4.7 4.8 14.9 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF1675 PF07897.6 CDI79346.1 - 4.1 7.1 20.1 4.8 6.9 14.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) MAPEG PF01124.13 CDI79346.1 - 4.5 6.8 4.8 18 4.9 3.3 1.9 1 1 0 1 1 1 0 MAPEG family Neur_chan_memb PF02932.11 CDI79346.1 - 5 6.9 22.2 6.5 6.5 15.4 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region CLPTM1 PF05602.7 CDI79346.1 - 5.1 5.7 15.4 6.1 5.4 10.7 1.1 1 0 0 1 1 1 0 Cleft lip and palate transmembrane protein 1 (CLPTM1) MRP-S26 PF14943.1 CDI79346.1 - 5.8 6.4 35.6 7.6 6.0 24.7 1.1 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 GPCR_chapero_1 PF11904.3 CDI79346.1 - 6.9 5.7 25.5 7.9 5.5 17.7 1.1 1 0 0 1 1 1 0 GPCR-chaperone CENP-T PF15511.1 CDI79346.1 - 7.5 5.6 32.9 9.1 5.4 22.8 1.0 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T SID-1_RNA_chan PF13965.1 CDI79346.1 - 7.7 4.5 17.0 11 4.1 11.8 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 FLO_LFY PF01698.11 CDI79346.1 - 9.3 4.9 28.3 14 4.3 19.6 1.2 1 0 0 1 1 1 0 Floricaula / Leafy protein SAGA-Tad1 PF12767.2 CDI79346.1 - 9.4 5.8 30.8 12 5.4 21.4 1.2 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit Lin-8 PF03353.10 CDI79346.1 - 9.4 5.4 36.2 12 5.0 25.1 1.0 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist DUF4045 PF13254.1 CDI79346.1 - 9.5 5.3 24.8 12 5.0 17.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) VIT1 PF01988.14 CDI79348.1 - 0.011 15.2 5.8 0.021 14.2 4.0 1.4 1 0 0 1 1 1 0 VIT family GAGA_bind PF06217.7 CDI79348.1 - 0.02 14.8 15.9 0.021 14.7 11.0 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family Adenosine_kin PF04008.9 CDI79348.1 - 0.066 12.7 0.7 0.15 11.5 0.2 1.8 1 1 0 2 2 2 0 Adenosine specific kinase CRT10 PF08728.5 CDI79348.1 - 0.12 10.2 10.3 0.13 10.2 7.2 1.0 1 0 0 1 1 1 0 CRT10 PLRV_ORF5 PF01690.12 CDI79348.1 - 0.2 10.7 17.9 0.24 10.4 12.4 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein DUF4045 PF13254.1 CDI79348.1 - 0.22 10.7 17.7 0.27 10.4 12.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) HGTP_anticodon2 PF12745.2 CDI79348.1 - 0.22 10.6 17.1 0.35 9.9 11.9 1.4 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs BPL_N PF09825.4 CDI79348.1 - 0.26 10.0 7.9 0.29 9.8 5.5 1.1 1 0 0 1 1 1 0 Biotin-protein ligase, N terminal Corona_nucleoca PF00937.13 CDI79348.1 - 0.44 9.4 22.5 0.59 9.0 15.6 1.2 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein LMBR1 PF04791.11 CDI79348.1 - 0.46 9.0 7.6 0.53 8.8 5.3 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein HlyD_2 PF12700.2 CDI79348.1 - 0.81 8.7 20.5 1.1 8.3 14.2 1.4 1 0 0 1 1 1 0 HlyD family secretion protein Afi1 PF07792.7 CDI79348.1 - 0.87 9.5 20.3 3.7 7.5 13.3 2.0 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking V_ATPase_I PF01496.14 CDI79348.1 - 1.7 6.3 15.1 2 6.2 10.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family BTV_NS2 PF04514.7 CDI79348.1 - 2.3 7.0 20.0 3.3 6.5 13.9 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Raftlin PF15250.1 CDI79348.1 - 3 6.2 21.6 4.2 5.7 15.0 1.2 1 0 0 1 1 1 0 Raftlin Peptidase_S64 PF08192.6 CDI79348.1 - 4.1 5.6 23.2 5.2 5.2 16.1 1.1 1 0 0 1 1 1 0 Peptidase family S64 Mem_trans PF03547.13 CDI79348.1 - 5.5 5.1 6.2 7 4.8 4.3 1.4 1 0 0 1 1 1 0 Membrane transport protein DUF4220 PF13968.1 CDI79348.1 - 5.6 5.9 9.9 8.6 5.3 6.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4220) DUF4613 PF15390.1 CDI79348.1 - 5.7 4.9 21.9 7.2 4.6 15.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) DUF4544 PF15077.1 CDI79348.1 - 5.8 6.3 13.3 10 5.5 9.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4544) Draxin PF15550.1 CDI79348.1 - 6.4 6.3 18.2 7.9 6.0 12.6 1.2 1 0 0 1 1 1 0 Draxin EutN_CcmL PF03319.8 CDI79348.1 - 7.8 6.9 7.0 1.5 9.2 0.6 2.8 2 1 1 3 3 3 0 Ethanolamine utilisation protein EutN/carboxysome Ycf1 PF05758.7 CDI79348.1 - 8.6 3.9 25.4 10 3.6 17.6 1.1 1 0 0 1 1 1 0 Ycf1 Med15 PF09606.5 CDI79351.1 - 0.00011 20.6 4.8 0.00011 20.6 3.4 1.2 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal CR6_interact PF10147.4 CDI79351.1 - 0.0024 17.2 0.3 0.0024 17.2 0.2 1.9 2 0 0 2 2 2 1 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 DUF4175 PF13779.1 CDI79351.1 - 0.15 9.6 12.2 0.17 9.5 8.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Spt20 PF12090.3 CDI79351.1 - 0.28 10.5 4.1 0.48 9.7 2.8 1.3 1 0 0 1 1 1 0 Spt20 family TraV PF09676.5 CDI79351.1 - 0.44 11.2 7.0 0.51 11.0 1.3 2.1 2 0 0 2 2 2 0 Type IV conjugative transfer system lipoprotein (TraV) Pex14_N PF04695.8 CDI79351.1 - 0.63 10.0 8.1 2 8.4 3.9 2.1 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Activator_LAG-3 PF11498.3 CDI79351.1 - 0.73 8.5 21.8 1.3 7.6 15.1 1.3 1 0 0 1 1 1 0 Transcriptional activator LAG-3 PAT1 PF09770.4 CDI79351.1 - 0.88 7.7 13.3 1.1 7.3 9.2 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Androgen_recep PF02166.11 CDI79351.1 - 1 8.1 8.6 1.3 7.8 5.9 1.2 1 0 0 1 1 1 0 Androgen receptor RAB3GAP2_N PF14655.1 CDI79351.1 - 1.1 8.1 4.2 1.6 7.6 2.9 1.2 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus DUF1840 PF08895.6 CDI79351.1 - 1.6 8.7 6.2 5.5 7.0 0.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1840) G0-G1_switch_2 PF15103.1 CDI79351.1 - 2.2 8.5 6.8 1.6 9.0 1.1 2.2 2 0 0 2 2 2 0 G0/G1 switch protein 2 OmpH PF03938.9 CDI79351.1 - 2.3 8.1 18.4 2.8 7.8 7.6 2.1 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) PHD_3 PF13922.1 CDI79351.1 - 2.3 8.5 7.8 3.4 7.9 4.2 2.1 2 0 0 2 2 2 0 PHD domain of transcriptional enhancer, Asx BAF1_ABF1 PF04684.8 CDI79351.1 - 5.3 5.7 14.8 7.5 5.2 10.3 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Serinc PF03348.10 CDI79358.1 - 3.7 6.1 22.7 0.28 9.8 4.1 2.3 2 0 0 2 2 2 0 Serine incorporator (Serinc) Ribosomal_60s PF00428.14 CDI79364.1 - 0.0011 19.3 11.9 0.0011 19.3 8.3 10.1 4 2 1 6 6 6 1 60s Acidic ribosomal protein BAF1_ABF1 PF04684.8 CDI79364.1 - 0.005 15.7 27.7 0.005 15.7 19.2 9.0 6 3 2 10 10 10 1 BAF1 / ABF1 chromatin reorganising factor DUF3915 PF13054.1 CDI79364.1 - 0.7 9.8 7.5 0.65 9.9 0.1 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF3915) La PF05383.12 CDI79384.1 - 3.5e-07 29.9 0.4 6.1e-07 29.1 0.3 1.3 1 0 0 1 1 1 1 La domain AAA_23 PF13476.1 CDI79384.1 - 0.013 15.7 29.2 0.018 15.3 20.2 1.1 1 0 0 1 1 1 0 AAA domain Herpes_BLLF1 PF05109.8 CDI79384.1 - 0.13 10.2 29.3 0.12 10.2 20.3 1.1 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) Borrelia_P83 PF05262.6 CDI79384.1 - 2.2 6.4 28.7 2.1 6.4 19.4 1.4 1 1 0 1 1 1 0 Borrelia P83/100 protein PAT1 PF09770.4 CDI79384.1 - 4.2 5.4 65.7 5.7 5.0 45.5 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Ycf1 PF05758.7 CDI79395.1 - 0.83 7.2 2.8 1.1 6.9 2.0 1.1 1 0 0 1 1 1 0 Ycf1 CDC45 PF02724.9 CDI79395.1 - 1.4 6.8 7.6 1.8 6.4 5.3 1.3 1 0 0 1 1 1 0 CDC45-like protein Spore_III_AF PF09581.5 CDI79396.1 - 3.6 7.4 6.8 0.41 10.4 1.6 1.7 2 0 0 2 2 2 0 Stage III sporulation protein AF (Spore_III_AF) PNK3P PF08645.6 CDI79397.1 - 1.4e-34 118.8 0.0 2.8e-22 78.8 0.0 2.4 2 0 0 2 2 2 2 Polynucleotide kinase 3 phosphatase AAA_33 PF13671.1 CDI79397.1 - 1.1e-13 51.2 0.2 1.1e-12 48.0 0.1 2.6 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 CDI79397.1 - 4.6e-06 25.8 0.4 0.0076 15.3 0.1 2.4 1 1 1 2 2 2 2 Zeta toxin AAA_16 PF13191.1 CDI79397.1 - 1.4e-05 25.1 0.1 4.9e-05 23.3 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 CDI79397.1 - 1.6e-05 25.0 0.0 4e-05 23.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain tRNA_lig_kinase PF08303.6 CDI79397.1 - 3.1e-05 23.9 0.0 4.9e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 tRNA ligase kinase domain DUF258 PF03193.11 CDI79397.1 - 0.00078 18.6 0.0 0.0017 17.5 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 G-alpha PF00503.15 CDI79397.1 - 0.002 16.8 1.2 0.0054 15.4 0.8 1.6 1 1 0 1 1 1 1 G-protein alpha subunit AAA_17 PF13207.1 CDI79397.1 - 0.0031 18.3 0.0 0.0068 17.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain cobW PF02492.14 CDI79397.1 - 0.0041 16.5 0.0 0.045 13.2 0.0 2.5 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_29 PF13555.1 CDI79397.1 - 0.0046 16.4 0.0 0.011 15.2 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain 6PF2K PF01591.13 CDI79397.1 - 0.0046 16.0 0.1 2.3 7.2 0.0 2.5 1 1 1 2 2 2 1 6-phosphofructo-2-kinase AAA_28 PF13521.1 CDI79397.1 - 0.0049 16.8 0.0 0.011 15.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 CDI79397.1 - 0.0074 16.5 0.3 0.037 14.3 0.2 2.1 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 CDI79397.1 - 0.009 15.7 0.1 0.033 13.9 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) MMR_HSR1 PF01926.18 CDI79397.1 - 0.01 15.7 0.0 0.031 14.2 0.0 1.8 2 0 0 2 2 1 0 50S ribosome-binding GTPase ABC_tran PF00005.22 CDI79397.1 - 0.016 15.4 0.0 0.04 14.2 0.0 1.7 1 0 0 1 1 1 0 ABC transporter NACHT PF05729.7 CDI79397.1 - 0.018 14.7 0.0 0.034 13.8 0.0 1.5 1 0 0 1 1 1 0 NACHT domain KTI12 PF08433.5 CDI79397.1 - 0.018 14.2 1.3 0.15 11.2 0.1 2.2 1 1 1 2 2 2 0 Chromatin associated protein KTI12 Miro PF08477.8 CDI79397.1 - 0.023 15.1 0.3 0.09 13.2 0.0 2.2 2 0 0 2 2 2 0 Miro-like protein HAD_2 PF13419.1 CDI79397.1 - 0.032 14.4 0.2 1.9 8.6 0.0 2.9 1 1 1 2 2 2 0 Haloacid dehalogenase-like hydrolase Mg_chelatase PF01078.16 CDI79397.1 - 0.033 13.3 0.0 0.15 11.1 0.0 1.9 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI ArgK PF03308.11 CDI79397.1 - 0.036 12.8 0.0 0.072 11.8 0.0 1.5 1 0 0 1 1 1 0 ArgK protein AAA_19 PF13245.1 CDI79397.1 - 0.052 13.3 0.0 0.12 12.1 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain AAA_14 PF13173.1 CDI79397.1 - 0.06 13.2 0.0 0.13 12.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 CDI79397.1 - 0.083 13.0 0.0 0.37 10.9 0.0 2.1 2 0 0 2 2 1 0 RNA helicase AAA_10 PF12846.2 CDI79397.1 - 0.12 11.8 0.0 0.21 10.9 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain V-ATPase_G PF03179.10 CDI79398.1 - 4.3e-10 39.8 12.0 1e-09 38.6 8.3 1.7 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit HrpE PF06188.7 CDI79398.1 - 0.31 10.7 10.7 0.11 12.1 4.5 2.0 1 1 1 2 2 2 0 HrpE/YscL/FliH and V-type ATPase subunit E ATP-synt_B PF00430.13 CDI79398.1 - 9.7 6.0 17.7 1.1 9.0 8.5 2.1 1 1 1 2 2 2 0 ATP synthase B/B' CF(0) RRM_6 PF14259.1 CDI79399.1 - 0.028 14.4 0.0 0.63 10.0 0.0 2.7 3 0 0 3 3 3 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF3995 PF13160.1 CDI79416.1 - 0.001 19.1 9.0 0.069 13.1 0.5 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF3995) Med15 PF09606.5 CDI79416.1 - 0.92 7.6 36.2 1.3 7.1 25.1 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF4056 PF13265.1 CDI79416.1 - 2.7 6.8 8.8 0.49 9.3 3.3 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF4056) TFIIA PF03153.8 CDI79416.1 - 2.9 7.6 20.9 4.6 7.0 14.5 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Mucin PF01456.12 CDI79429.1 - 0.0033 17.1 26.4 0.0041 16.9 18.3 1.2 1 0 0 1 1 1 1 Mucin-like glycoprotein DUF3439 PF11921.3 CDI79429.1 - 0.011 15.4 11.1 0.014 15.1 7.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Dicty_REP PF05086.7 CDI79429.1 - 0.1 10.3 4.7 0.098 10.4 3.3 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein SSP160 PF06933.6 CDI79429.1 - 0.31 8.9 23.7 0.34 8.8 16.4 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Tir_receptor_C PF07489.6 CDI79429.1 - 0.91 9.2 15.6 1.1 8.9 10.8 1.1 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) C-terminus OAD_gamma PF04277.8 CDI79429.1 - 2.5 8.5 15.9 33 4.9 8.9 2.1 1 1 1 2 2 2 0 Oxaloacetate decarboxylase, gamma chain Gp23 PF07068.6 CDI79429.1 - 3.1 6.2 11.7 3.7 5.9 8.1 1.0 1 0 0 1 1 1 0 Major capsid protein Gp23 Tetraspannin PF00335.15 CDI79436.1 - 0.001 18.3 1.6 0.0015 17.8 1.1 1.3 1 0 0 1 1 1 1 Tetraspanin family MipZ PF09140.6 CDI79436.1 - 0.14 11.1 1.3 0.18 10.8 0.9 1.2 1 0 0 1 1 1 0 ATPase MipZ DUF2215 PF10225.4 CDI79436.1 - 0.22 10.9 9.4 0.34 10.3 6.5 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) PMSI1 PF15322.1 CDI79436.1 - 0.38 9.7 19.7 0.63 9.0 13.7 1.3 1 0 0 1 1 1 0 Protein missing in infertile sperm 1, putative DUF2146 PF10220.4 CDI79436.1 - 0.46 8.4 11.7 0.55 8.1 8.1 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2146) Na_trans_assoc PF06512.8 CDI79436.1 - 0.57 10.1 7.8 0.71 9.7 5.4 1.1 1 0 0 1 1 1 0 Sodium ion transport-associated DUF4551 PF15087.1 CDI79436.1 - 0.6 8.4 17.4 0.66 8.2 12.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) PAT1 PF09770.4 CDI79436.1 - 0.88 7.7 19.9 0.98 7.5 13.8 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Neur_chan_memb PF02932.11 CDI79436.1 - 1.5 8.6 12.7 4.8 6.9 8.9 1.7 1 1 1 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region PAP1 PF08601.5 CDI79436.1 - 1.8 8.1 31.2 2.5 7.6 21.7 1.2 1 0 0 1 1 1 0 Transcription factor PAP1 CDC27 PF09507.5 CDI79436.1 - 4.1 6.5 22.1 6.2 5.9 15.3 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 SnoaL_4 PF13577.1 CDI79436.1 - 4.7 7.1 5.7 1.2 9.0 1.7 1.6 2 0 0 2 2 2 0 SnoaL-like domain SpoIIIAH PF12685.2 CDI79436.1 - 8.6 5.8 28.3 2.1e+02 1.2 19.6 2.2 1 1 0 1 1 1 0 SpoIIIAH-like protein FUN14 PF04930.10 CDI79436.1 - 8.9 6.6 7.1 62 3.9 4.5 2.3 1 1 0 1 1 1 0 FUN14 family N6_N4_Mtase PF01555.13 CDI79445.1 - 0.16 11.4 18.5 0.56 9.6 0.0 4.1 1 1 2 3 3 3 0 DNA methylase PAT1 PF09770.4 CDI79453.1 - 2.6 6.2 31.0 2 6.5 9.4 2.1 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 FHIPEP PF00771.15 CDI79453.1 - 7.1 4.8 7.4 1.5 7.0 1.0 2.3 2 1 0 2 2 2 0 FHIPEP family Spt20 PF12090.3 CDI79458.1 - 0.0081 15.5 15.6 0.37 10.1 5.8 2.4 2 0 0 2 2 2 2 Spt20 family DDHD PF02862.12 CDI79458.1 - 0.052 13.3 10.6 2.1 8.0 4.1 2.2 2 0 0 2 2 2 0 DDHD domain Peptidase_S49_N PF08496.5 CDI79458.1 - 0.054 13.2 12.5 0.18 11.5 1.9 2.4 2 0 0 2 2 2 0 Peptidase family S49 N-terminal DUF1107 PF06526.7 CDI79458.1 - 0.19 11.5 1.3 0.33 10.7 0.0 2.1 2 0 0 2 2 1 0 Protein of unknown function (DUF1107) Peroxin-13_N PF04088.8 CDI79458.1 - 0.31 10.9 5.8 0.52 10.2 0.4 2.3 2 0 0 2 2 2 0 Peroxin 13, N-terminal region PH_4 PF15404.1 CDI79458.1 - 0.4 10.1 12.7 1.4 8.3 4.3 2.3 2 0 0 2 2 2 0 Pleckstrin homology domain FimP PF09766.4 CDI79458.1 - 0.62 9.0 29.0 1.9 7.4 12.6 2.3 2 0 0 2 2 2 0 Fms-interacting protein AAA_23 PF13476.1 CDI79458.1 - 0.85 9.9 15.7 3 8.1 6.1 2.2 2 0 0 2 2 2 0 AAA domain Phage_pRha PF09669.5 CDI79458.1 - 1.2 9.5 5.5 5.4 7.4 0.5 2.4 2 0 0 2 2 2 0 Phage regulatory protein Rha (Phage_pRha) Herpes_UL87 PF03043.9 CDI79458.1 - 1.9 6.7 9.4 1.7 6.9 2.4 2.1 2 0 0 2 2 2 0 Herpesvirus UL87 family SPX PF03105.14 CDI79458.1 - 6.9 6.3 14.7 2.3 7.9 3.2 2.1 2 0 0 2 2 2 0 SPX domain Dala_Dala_lig_N PF01820.16 CDI79458.1 - 7.5 6.8 9.1 3.1 8.1 1.9 2.5 2 0 0 2 2 2 0 D-ala D-ala ligase N-terminus DUF913 PF06025.7 CDI79458.1 - 7.6 5.1 8.2 0.84 8.3 1.1 2.2 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) Rxt3 PF08642.5 CDI79458.1 - 8.2 6.7 12.8 2.9 8.1 0.1 2.5 2 1 0 2 2 2 0 Histone deacetylation protein Rxt3 DnaJ-X PF14308.1 CDI79458.1 - 8.3 5.6 16.1 3 7.0 3.0 2.3 2 0 0 2 2 2 0 X-domain of DnaJ-containing FLO_LFY PF01698.11 CDI79458.1 - 9.4 4.9 13.7 8.7 5.0 4.2 2.3 2 0 0 2 2 2 0 Floricaula / Leafy protein DUF912 PF06024.7 CDI79458.1 - 9.5 6.3 12.0 1.6 8.8 2.7 2.4 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF1510 PF07423.6 CDI79459.1 - 4.4 6.6 37.3 4.8 6.4 25.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) SAPS PF04499.10 CDI79459.1 - 8.3 4.9 30.4 9.2 4.7 21.1 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Mucin PF01456.12 CDI79461.1 - 0.00095 18.9 9.5 0.00095 18.9 6.6 1.7 2 0 0 2 2 2 1 Mucin-like glycoprotein Ycf1 PF05758.7 CDI79461.1 - 0.14 9.8 16.7 0.17 9.6 11.6 1.1 1 0 0 1 1 1 0 Ycf1 DUF1675 PF07897.6 CDI79461.1 - 2.3 8.0 21.7 3.1 7.6 15.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) Cellulose_synt PF03552.9 CDI79461.1 - 3 6.0 6.2 4.3 5.5 4.3 1.2 1 0 0 1 1 1 0 Cellulose synthase Herpes_env PF01673.13 CDI79463.1 - 0.69 8.3 16.6 1 7.8 11.5 1.3 1 0 0 1 1 1 0 Herpesvirus putative major envelope glycoprotein GDI PF00996.13 CDI79465.1 - 2.8e-19 68.7 0.0 9.1e-10 37.4 0.0 4.3 5 0 0 5 5 5 3 GDP dissociation inhibitor Activator_LAG-3 PF11498.3 CDI79466.1 - 0.0015 17.4 45.9 0.0015 17.4 31.8 15.2 8 3 8 16 16 16 1 Transcriptional activator LAG-3 BAF1_ABF1 PF04684.8 CDI79466.1 - 0.0022 16.9 8.0 0.0022 16.9 5.6 28.0 13 5 13 26 26 26 1 BAF1 / ABF1 chromatin reorganising factor Herpes_UL87 PF03043.9 CDI79466.1 - 0.0069 14.8 0.0 0.0069 14.8 0.0 8.5 6 2 2 8 8 8 1 Herpesvirus UL87 family WD40 PF00400.27 CDI79478.1 - 1.3e-09 37.5 10.0 0.12 12.3 0.4 5.6 5 0 0 5 5 5 5 WD domain, G-beta repeat Med15 PF09606.5 CDI79484.1 - 0.24 9.5 34.8 0.33 9.1 24.1 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Herpes_DNAp_acc PF04929.7 CDI79484.1 - 0.34 9.8 10.9 0.44 9.4 7.5 1.2 1 0 0 1 1 1 0 Herpes DNA replication accessory factor FimP PF09766.4 CDI79486.1 - 9.9e-07 28.1 45.4 0.00059 19.0 7.5 2.3 2 0 0 2 2 2 2 Fms-interacting protein Spore_coat_CotO PF14153.1 CDI79486.1 - 0.0002 20.8 36.5 0.015 14.7 13.4 2.4 2 0 0 2 2 2 2 Spore coat protein CotO Serinc PF03348.10 CDI79486.1 - 0.00027 19.7 22.9 0.00099 17.9 6.6 2.1 2 0 0 2 2 2 2 Serine incorporator (Serinc) Ycf1 PF05758.7 CDI79486.1 - 0.00045 18.0 19.2 0.0028 15.4 6.3 2.0 2 0 0 2 2 2 2 Ycf1 DUF4175 PF13779.1 CDI79486.1 - 0.0014 16.4 18.7 0.0014 16.4 13.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4175) Band_3_cyto PF07565.8 CDI79486.1 - 0.0017 17.9 24.2 0.021 14.3 1.2 2.5 2 0 0 2 2 2 2 Band 3 cytoplasmic domain SprA-related PF12118.3 CDI79486.1 - 0.0032 16.8 24.1 0.0032 16.8 16.7 2.8 3 0 0 3 3 2 1 SprA-related family Suf PF05843.9 CDI79486.1 - 0.0034 17.1 11.0 0.0034 17.1 7.6 2.7 2 1 0 2 2 1 1 Suppressor of forked protein (Suf) PAT1 PF09770.4 CDI79486.1 - 0.0038 15.5 76.6 0.023 12.9 26.9 2.1 2 0 0 2 2 2 2 Topoisomerase II-associated protein PAT1 NARP1 PF12569.3 CDI79486.1 - 0.0039 16.0 36.3 0.096 11.4 12.5 2.2 2 0 0 2 2 2 2 NMDA receptor-regulated protein 1 SAGA-Tad1 PF12767.2 CDI79486.1 - 0.0086 15.7 34.7 0.23 11.0 11.0 2.3 2 0 0 2 2 2 2 Transcriptional regulator of RNA polII, SAGA, subunit PIH1 PF08190.7 CDI79486.1 - 0.0096 15.4 33.6 0.021 14.2 10.3 2.5 2 0 0 2 2 2 1 pre-RNA processing PIH1/Nop17 SPX PF03105.14 CDI79486.1 - 0.01 15.6 25.1 0.23 11.1 4.0 2.1 2 0 0 2 2 2 0 SPX domain DUF2052 PF09747.4 CDI79486.1 - 0.016 15.1 38.2 0.086 12.7 15.1 2.2 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) NPR3 PF03666.8 CDI79486.1 - 0.018 13.5 24.3 0.15 10.5 8.8 2.2 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 Herpes_UL87 PF03043.9 CDI79486.1 - 0.032 12.6 11.6 0.1 11.0 8.0 1.7 1 1 0 1 1 1 0 Herpesvirus UL87 family Gti1_Pac2 PF09729.4 CDI79486.1 - 0.046 13.5 19.6 0.6 9.9 1.1 2.3 2 0 0 2 2 2 0 Gti1/Pac2 family DUF2126 PF09899.4 CDI79486.1 - 0.054 11.5 23.7 0.084 10.8 6.6 2.2 2 0 0 2 2 2 0 Putative amidoligase enzyme (DUF2126) Alpha_E3_glycop PF01563.11 CDI79486.1 - 0.074 12.8 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 Alphavirus E3 glycoprotein Otopetrin PF03189.8 CDI79486.1 - 0.093 11.7 7.0 0.22 10.4 0.4 2.1 2 0 0 2 2 2 0 Otopetrin POP1 PF06978.6 CDI79486.1 - 0.099 12.2 22.6 0.29 10.7 7.1 2.3 2 0 0 2 2 2 0 Ribonucleases P/MRP protein subunit POP1 SR-25 PF10500.4 CDI79486.1 - 0.15 11.5 27.8 0.96 8.8 3.9 2.3 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Pox_Ag35 PF03286.9 CDI79486.1 - 0.15 11.5 25.4 0.077 12.5 6.3 2.5 2 1 0 2 2 2 0 Pox virus Ag35 surface protein DUF4045 PF13254.1 CDI79486.1 - 0.16 11.2 29.5 0.56 9.4 4.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4045) PLRV_ORF5 PF01690.12 CDI79486.1 - 0.24 10.5 24.3 0.98 8.4 7.7 2.1 2 0 0 2 2 2 0 Potato leaf roll virus readthrough protein Glyco_transf_15 PF01793.11 CDI79486.1 - 0.34 9.8 25.8 0.64 8.9 9.1 2.2 2 0 0 2 2 2 0 Glycolipid 2-alpha-mannosyltransferase DUF572 PF04502.8 CDI79486.1 - 0.35 10.0 29.8 0.42 9.7 5.6 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF572) CDC45 PF02724.9 CDI79486.1 - 0.39 8.6 28.1 0.68 7.8 10.4 2.1 2 0 0 2 2 2 0 CDC45-like protein Raftlin PF15250.1 CDI79486.1 - 0.45 8.9 29.7 0.19 10.2 2.9 2.2 2 0 0 2 2 2 0 Raftlin DUF966 PF06136.8 CDI79486.1 - 0.59 9.4 24.7 1.1 8.5 7.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF966) eIF-3_zeta PF05091.7 CDI79486.1 - 0.68 8.4 40.1 0.9 8.0 6.2 2.1 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Dynamin_N PF00350.18 CDI79486.1 - 0.7 9.6 15.9 1.7 8.4 0.4 2.3 2 0 0 2 2 2 0 Dynamin family Vfa1 PF08432.5 CDI79486.1 - 0.76 9.7 32.1 3.1 7.7 11.7 2.4 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 Hid1 PF12722.2 CDI79486.1 - 0.94 7.0 33.1 0.99 6.9 4.9 2.1 2 0 0 2 2 2 0 High-temperature-induced dauer-formation protein SeqA PF03925.8 CDI79486.1 - 0.95 9.1 27.8 0.74 9.4 3.1 2.4 2 0 0 2 2 2 0 SeqA protein GAGA_bind PF06217.7 CDI79486.1 - 0.97 9.3 33.5 1.6 8.6 11.8 2.1 2 0 0 2 2 2 0 GAGA binding protein-like family SOBP PF15279.1 CDI79486.1 - 1 9.6 32.6 2.2 8.5 6.3 2.1 2 0 0 2 2 2 0 Sine oculis-binding protein DDRGK PF09756.4 CDI79486.1 - 1.1 8.6 47.2 1.5 8.1 19.0 2.4 2 0 0 2 2 2 0 DDRGK domain Bud13 PF09736.4 CDI79486.1 - 1.1 9.5 43.7 3.8 7.7 7.7 2.3 2 0 0 2 2 2 0 Pre-mRNA-splicing factor of RES complex DDHD PF02862.12 CDI79486.1 - 1.3 8.8 34.3 0.24 11.1 3.4 2.3 2 0 0 2 2 2 0 DDHD domain Parvo_coat PF00740.13 CDI79486.1 - 1.4 7.7 33.3 1.2 7.9 7.0 2.1 2 0 0 2 2 2 0 Parvovirus coat protein VP2 DHHW PF14286.1 CDI79486.1 - 1.6 7.9 25.3 0.43 9.8 6.9 2.3 2 0 0 2 2 2 0 DHHW protein TT_ORF1 PF02956.9 CDI79486.1 - 1.9 6.8 21.9 2.3 6.5 1.5 2.1 2 0 0 2 2 2 0 TT viral orf 1 EPL1 PF10513.4 CDI79486.1 - 2 8.6 30.0 4.3 7.5 4.9 2.3 2 0 0 2 2 2 0 Enhancer of polycomb-like Neur_chan_memb PF02932.11 CDI79486.1 - 2.2 8.1 22.7 4.4 7.1 3.3 2.2 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Plasmodium_Vir PF05795.6 CDI79486.1 - 2.5 7.1 14.6 3.8 6.6 4.6 2.1 2 0 0 2 2 2 0 Plasmodium vivax Vir protein XAP5 PF04921.9 CDI79486.1 - 2.7 7.5 20.4 4.4 6.8 1.7 2.3 2 0 0 2 2 2 0 XAP5, circadian clock regulator Ndc1_Nup PF09531.5 CDI79486.1 - 4 5.7 27.8 0.99 7.7 8.3 2.1 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup SRP-alpha_N PF04086.8 CDI79486.1 - 4.1 6.7 33.0 0.72 9.1 8.5 2.2 2 0 0 2 2 2 0 Signal recognition particle, alpha subunit, N-terminal Lin-8 PF03353.10 CDI79486.1 - 4.1 6.6 35.4 4.9 6.3 12.8 2.3 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist Zip PF02535.17 CDI79486.1 - 4.6 6.1 19.3 0.59 9.0 2.3 2.2 2 0 0 2 2 2 0 ZIP Zinc transporter DUF605 PF04652.11 CDI79486.1 - 5 6.4 49.5 4.2 6.6 16.0 2.2 2 0 0 2 2 2 0 Vta1 like DUF702 PF05142.7 CDI79486.1 - 5.2 7.2 33.5 3.8 7.6 5.8 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF702) Peptidase_C58 PF03543.9 CDI79486.1 - 5.3 6.4 40.5 1.5 8.2 6.5 2.4 2 0 0 2 2 2 0 Yersinia/Haemophilus virulence surface antigen RR_TM4-6 PF06459.7 CDI79486.1 - 5.8 6.7 38.4 1.1 9.0 6.3 2.2 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 CRF1 PF10380.4 CDI79486.1 - 6.4 7.1 22.2 3.8 7.8 1.7 2.6 2 0 0 2 2 2 0 Transcription factor CRF1 SpoIIP PF07454.6 CDI79486.1 - 6.9 5.7 26.8 2.2 7.3 8.8 2.3 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) Nucleo_P87 PF07267.6 CDI79486.1 - 8.4 4.9 26.7 0.21 10.2 2.5 2.1 2 0 0 2 2 2 0 Nucleopolyhedrovirus capsid protein P87 Baculo_PP31 PF05311.6 CDI79486.1 - 9 5.4 36.8 0.4 9.9 4.7 2.3 2 0 0 2 2 2 0 Baculovirus 33KDa late protein (PP31) TRAP_alpha PF03896.11 CDI79486.1 - 9 5.1 14.1 0.24 10.3 2.6 2.1 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit YqfQ PF14181.1 CDI79496.1 - 0.00047 20.2 8.3 0.00055 20.0 5.8 1.0 1 0 0 1 1 1 1 YqfQ-like protein FimP PF09766.4 CDI79496.1 - 0.0067 15.5 19.5 0.0072 15.4 13.5 1.0 1 0 0 1 1 1 1 Fms-interacting protein Peptidase_S49_N PF08496.5 CDI79496.1 - 0.0071 16.1 7.3 0.0082 15.9 5.1 1.2 1 0 0 1 1 1 1 Peptidase family S49 N-terminal DUF4512 PF14975.1 CDI79496.1 - 0.015 16.0 6.5 0.022 15.5 4.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4512) Tim54 PF11711.3 CDI79496.1 - 0.023 13.2 3.3 0.023 13.3 2.3 1.0 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 RNA_pol_Rpc4 PF05132.9 CDI79496.1 - 0.036 14.0 7.2 0.044 13.7 5.0 1.1 1 0 0 1 1 1 0 RNA polymerase III RPC4 FLO_LFY PF01698.11 CDI79496.1 - 0.052 12.3 7.5 0.052 12.3 5.2 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein AAA_11 PF13086.1 CDI79496.1 - 0.066 12.7 8.9 0.075 12.5 6.2 1.0 1 0 0 1 1 1 0 AAA domain Apc15p PF05841.6 CDI79496.1 - 0.094 13.4 16.1 0.11 13.2 11.2 1.1 1 0 0 1 1 1 0 Apc15p protein AUX_IAA PF02309.11 CDI79496.1 - 0.1 12.3 8.5 0.11 12.2 5.9 1.0 1 0 0 1 1 1 0 AUX/IAA family Serinc PF03348.10 CDI79496.1 - 0.13 10.9 8.7 0.14 10.8 6.1 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) DDHD PF02862.12 CDI79496.1 - 0.18 11.5 10.5 0.21 11.3 7.3 1.1 1 0 0 1 1 1 0 DDHD domain PPP4R2 PF09184.6 CDI79496.1 - 0.21 11.1 7.2 0.2 11.1 5.0 1.0 1 0 0 1 1 1 0 PPP4R2 YfhO PF09586.5 CDI79496.1 - 0.21 9.5 5.2 0.2 9.6 3.6 1.0 1 0 0 1 1 1 0 Bacterial membrane protein YfhO Sporozoite_P67 PF05642.6 CDI79496.1 - 0.21 9.3 4.1 0.23 9.2 2.9 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF3408 PF11888.3 CDI79496.1 - 0.27 11.1 7.9 0.29 11.0 5.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) Peroxin-13_N PF04088.8 CDI79496.1 - 0.29 11.0 4.5 0.34 10.8 3.2 1.1 1 0 0 1 1 1 0 Peroxin 13, N-terminal region Peptidase_U57 PF05582.7 CDI79496.1 - 0.34 9.8 7.1 0.36 9.7 5.0 1.0 1 0 0 1 1 1 0 YabG peptidase U57 Band_3_cyto PF07565.8 CDI79496.1 - 0.39 10.1 11.9 0.43 10.0 8.3 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Folate_carrier PF01770.13 CDI79496.1 - 0.44 9.0 5.6 0.46 8.9 3.9 1.0 1 0 0 1 1 1 0 Reduced folate carrier PBP1_TM PF14812.1 CDI79496.1 - 0.45 10.8 5.7 0.6 10.4 4.0 1.1 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal PAT1 PF09770.4 CDI79496.1 - 0.48 8.6 28.9 0.52 8.4 20.1 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 CPSF100_C PF13299.1 CDI79496.1 - 0.49 10.5 9.5 0.55 10.4 6.6 1.1 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Dala_Dala_lig_N PF01820.16 CDI79496.1 - 0.5 10.6 4.3 0.56 10.5 3.0 1.2 1 0 0 1 1 1 0 D-ala D-ala ligase N-terminus CobT PF06213.7 CDI79496.1 - 0.55 9.3 8.3 0.64 9.1 5.7 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT GPCR_chapero_1 PF11904.3 CDI79496.1 - 0.57 9.2 9.6 0.6 9.1 6.7 1.0 1 0 0 1 1 1 0 GPCR-chaperone PIH1 PF08190.7 CDI79496.1 - 0.58 9.5 14.1 0.59 9.5 9.8 1.0 1 0 0 1 1 1 0 pre-RNA processing PIH1/Nop17 EIIBC-GUT_N PF03612.9 CDI79496.1 - 0.61 9.6 7.6 0.68 9.5 5.2 1.1 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus DUF2828 PF11443.3 CDI79496.1 - 0.67 8.0 7.4 0.72 7.9 5.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Mem_trans PF03547.13 CDI79496.1 - 0.76 8.0 3.1 0.76 8.0 2.2 1.1 1 0 0 1 1 1 0 Membrane transport protein YABBY PF04690.8 CDI79496.1 - 0.77 9.9 7.5 0.78 9.9 5.2 1.1 1 0 0 1 1 1 0 YABBY protein Gag_spuma PF03276.9 CDI79496.1 - 0.77 8.0 25.4 0.84 7.8 17.6 1.0 1 0 0 1 1 1 0 Spumavirus gag protein Pex26 PF07163.7 CDI79496.1 - 0.84 8.4 7.8 1 8.2 5.4 1.1 1 0 0 1 1 1 0 Pex26 protein Baculo_PP31 PF05311.6 CDI79496.1 - 0.84 8.8 11.2 0.91 8.7 7.8 1.0 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) Med19 PF10278.4 CDI79496.1 - 0.84 9.2 7.7 0.99 9.0 5.3 1.1 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 Hom_end_hint PF05203.11 CDI79496.1 - 0.87 9.2 7.1 0.96 9.1 4.9 1.1 1 0 0 1 1 1 0 Hom_end-associated Hint FAM176 PF14851.1 CDI79496.1 - 0.9 9.2 5.9 1.1 8.9 4.1 1.1 1 0 0 1 1 1 0 FAM176 family DUF3381 PF11861.3 CDI79496.1 - 0.94 8.9 14.0 1.2 8.5 9.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) TFIIA PF03153.8 CDI79496.1 - 0.95 9.2 22.5 1 9.2 15.6 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RIC3 PF15361.1 CDI79496.1 - 0.95 9.6 10.9 1.1 9.4 7.5 1.1 1 0 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 Ycf1 PF05758.7 CDI79496.1 - 0.96 7.0 10.7 1.1 6.9 7.4 1.0 1 0 0 1 1 1 0 Ycf1 DUF2215 PF10225.4 CDI79496.1 - 1.1 8.6 4.8 1.1 8.6 3.3 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) Ctr PF04145.10 CDI79496.1 - 1.1 9.2 7.4 1.4 8.9 5.1 1.2 1 0 0 1 1 1 0 Ctr copper transporter family DUF3708 PF12501.3 CDI79496.1 - 1.2 8.9 3.3 1.2 8.9 2.3 1.2 1 0 0 1 1 1 0 Phosphate ATP-binding cassette transporter Suf PF05843.9 CDI79496.1 - 1.3 8.6 16.1 1.5 8.5 11.1 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF3371 PF11851.3 CDI79496.1 - 1.4 9.6 17.8 1.9 9.1 12.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3371) Pex16 PF08610.5 CDI79496.1 - 1.4 7.8 12.6 1.5 7.6 8.8 1.1 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) Fe_bilin_red PF05996.7 CDI79496.1 - 1.4 8.3 12.2 1.6 8.1 8.4 1.1 1 0 0 1 1 1 0 Ferredoxin-dependent bilin reductase OATP PF03137.15 CDI79496.1 - 1.4 6.8 9.4 1.5 6.7 6.5 1.0 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family IncA PF04156.9 CDI79496.1 - 1.5 8.3 19.6 1.7 8.2 13.6 1.2 1 0 0 1 1 1 0 IncA protein FAM60A PF15396.1 CDI79496.1 - 1.5 8.4 9.4 1.9 8.1 6.5 1.1 1 0 0 1 1 1 0 Protein Family FAM60A Hid1 PF12722.2 CDI79496.1 - 1.7 6.2 14.4 2 6.0 10.0 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Afi1 PF07792.7 CDI79496.1 - 1.7 8.6 12.2 1.9 8.5 8.5 1.1 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Plasmodium_Vir PF05795.6 CDI79496.1 - 1.8 7.6 4.1 1.9 7.5 2.9 1.0 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Neur_chan_memb PF02932.11 CDI79496.1 - 1.8 8.3 6.8 2 8.2 4.7 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region RED_N PF07808.8 CDI79496.1 - 1.9 7.6 21.2 2.3 7.3 14.7 1.1 1 0 0 1 1 1 0 RED-like protein N-terminal region DUF1980 PF09323.5 CDI79496.1 - 1.9 8.2 8.5 2.2 7.9 5.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) ATAD4 PF15321.1 CDI79496.1 - 2 9.5 14.0 2.4 9.2 9.7 1.1 1 0 0 1 1 1 0 ATPase family AAA domain containing 4 FCP1_C PF09309.5 CDI79496.1 - 2 7.6 17.2 2.4 7.4 11.9 1.1 1 0 0 1 1 1 0 FCP1, C-terminal Pex14_N PF04695.8 CDI79496.1 - 2.1 8.4 19.3 2.7 8.0 13.4 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region PH_4 PF15404.1 CDI79496.1 - 2.1 7.8 11.0 2.5 7.5 7.7 1.1 1 0 0 1 1 1 0 Pleckstrin homology domain RR_TM4-6 PF06459.7 CDI79496.1 - 2.2 8.1 12.3 2.6 7.8 8.5 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 zf-DHHC PF01529.15 CDI79496.1 - 2.2 7.6 6.7 2.8 7.3 4.6 1.3 1 0 0 1 1 1 0 DHHC palmitoyltransferase SID-1_RNA_chan PF13965.1 CDI79496.1 - 2.2 6.3 5.3 2.4 6.2 3.7 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DUF3043 PF11241.3 CDI79496.1 - 2.5 7.6 6.8 3 7.3 4.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) Otopetrin PF03189.8 CDI79496.1 - 2.5 7.0 5.6 2.5 6.9 3.3 1.3 1 1 0 1 1 1 0 Otopetrin DUF3260 PF11658.3 CDI79496.1 - 2.7 6.0 10.1 2.9 5.9 7.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3260) DUF1800 PF08811.6 CDI79496.1 - 2.7 6.8 14.3 2.7 6.8 9.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1800) BRF1 PF07741.8 CDI79496.1 - 2.8 8.2 14.6 4.2 7.6 10.1 1.3 1 0 0 1 1 1 0 Brf1-like TBP-binding domain DUF2946 PF11162.3 CDI79496.1 - 3 8.0 7.8 3.8 7.7 5.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2946) Wound_ind PF08186.6 CDI79496.1 - 4.1 7.3 5.9 3.3e+02 1.2 4.2 2.3 1 1 0 1 1 1 0 Wound-inducible basic protein family SeqA PF03925.8 CDI79496.1 - 4.4 6.9 11.1 5.3 6.6 7.7 1.1 1 0 0 1 1 1 0 SeqA protein DUF4407 PF14362.1 CDI79496.1 - 4.5 6.1 16.6 5.3 5.9 11.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) AIF_C PF14721.1 CDI79496.1 - 4.7 7.4 12.1 5.9 7.1 8.4 1.1 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Zip PF02535.17 CDI79496.1 - 4.8 6.0 6.4 5.6 5.8 4.4 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter CDC45 PF02724.9 CDI79496.1 - 5 5.0 12.6 5.8 4.8 8.7 1.0 1 0 0 1 1 1 0 CDC45-like protein Glycoprotein_B PF00606.13 CDI79496.1 - 5.1 5.0 10.6 5.4 4.9 7.3 1.0 1 0 0 1 1 1 0 Herpesvirus Glycoprotein B FliP PF00813.15 CDI79496.1 - 5.3 6.6 5.5 6.2 6.4 3.8 1.1 1 0 0 1 1 1 0 FliP family Gti1_Pac2 PF09729.4 CDI79496.1 - 5.5 6.8 10.5 6.8 6.5 7.3 1.1 1 0 0 1 1 1 0 Gti1/Pac2 family FHIPEP PF00771.15 CDI79496.1 - 6 5.0 8.0 6.1 5.0 5.6 1.1 1 0 0 1 1 1 0 FHIPEP family DUF3373 PF11853.3 CDI79496.1 - 6.3 5.1 11.7 6.8 5.1 8.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) Endonuc_Holl PF10107.4 CDI79496.1 - 7.2 6.2 12.9 8.3 6.0 8.9 1.1 1 0 0 1 1 1 0 Endonuclease related to archaeal Holliday junction resolvase Orbi_VP6 PF01516.11 CDI79496.1 - 7.5 5.5 8.5 8.9 5.2 5.9 1.0 1 0 0 1 1 1 0 Orbivirus helicase VP6 DDRGK PF09756.4 CDI79496.1 - 8.2 5.7 20.7 10 5.4 14.3 1.1 1 0 0 1 1 1 0 DDRGK domain TMEM51 PF15345.1 CDI79496.1 - 8.5 5.9 15.0 10 5.7 10.4 1.1 1 0 0 1 1 1 0 Transmembrane protein 51 MIase PF02426.11 CDI79496.1 - 9 6.1 8.6 0.41 10.4 0.6 2.2 1 1 2 3 3 2 0 Muconolactone delta-isomerase DUF2149 PF09919.4 CDI79496.1 - 9 6.4 7.7 12 6.0 5.3 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2149) Peptidase_S15 PF02129.13 CDI79496.1 - 9.6 5.5 12.7 12 5.2 8.8 1.1 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) DUF4557 PF15101.1 CDI79496.1 - 9.7 5.9 26.7 12 5.6 18.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) Fumarate_red_D PF02313.12 CDI79498.1 - 0.028 14.2 3.6 3.4 7.5 0.0 2.5 2 1 0 2 2 2 0 Fumarate reductase subunit D Fe-S_assembly PF04384.8 CDI79498.1 - 0.089 13.1 0.1 21 5.5 0.0 2.3 2 0 0 2 2 2 0 Iron-sulphur cluster assembly CP12 PF02672.10 CDI79498.1 - 2.4 8.6 4.9 22 5.5 0.1 2.2 2 0 0 2 2 2 0 CP12 domain CT47 PF15623.1 CDI79507.1 - 0.73 9.5 24.6 0.041 13.6 13.3 1.6 2 0 0 2 2 2 0 Cancer/testis gene family 47 SR-25 PF10500.4 CDI79509.1 - 0.25 10.7 83.4 0.11 12.0 39.0 2.2 1 1 1 2 2 2 0 Nuclear RNA-splicing-associated protein Pkinase PF00069.20 CDI79515.1 - 1.6e-08 33.9 0.0 3.6e-07 29.6 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDI79515.1 - 0.00044 19.3 0.0 0.00076 18.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase DUF788 PF05620.6 CDI79515.1 - 0.5 10.2 2.3 1 9.2 1.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF788) EF-hand_1 PF00036.27 CDI79520.1 - 1.5e-39 130.2 10.7 2.6e-09 35.6 0.1 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 CDI79520.1 - 2.8e-35 120.2 4.3 1.3e-18 66.8 0.4 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 CDI79520.1 - 7.5e-33 111.9 11.0 6.7e-17 60.8 0.4 4.2 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.1 CDI79520.1 - 1.7e-27 92.8 7.1 1.9e-09 36.5 0.1 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 CDI79520.1 - 7.5e-26 88.2 7.7 1.3e-06 27.4 0.1 4.3 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.1 CDI79520.1 - 1.8e-13 50.1 0.1 6.8e-08 32.3 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.2 CDI79520.1 - 5.5e-09 35.6 0.3 0.00057 19.5 0.1 2.4 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 CDI79520.1 - 4.4e-08 33.1 0.0 0.011 15.7 0.0 2.2 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region UPF0154 PF03672.8 CDI79520.1 - 5e-05 22.8 0.0 0.34 10.5 0.0 2.7 3 0 0 3 3 3 2 Uncharacterised protein family (UPF0154) EFhand_Ca_insen PF08726.5 CDI79520.1 - 0.00086 19.2 0.9 0.0097 15.8 0.0 2.4 2 1 0 2 2 2 1 Ca2+ insensitive EF hand Caleosin PF05042.8 CDI79520.1 - 0.0017 17.9 0.0 0.13 11.7 0.0 2.5 2 1 0 2 2 2 1 Caleosin related protein TerB PF05099.8 CDI79520.1 - 0.0028 17.3 0.5 0.43 10.3 0.0 2.6 1 1 1 2 2 2 1 Tellurite resistance protein TerB YqeY PF09424.5 CDI79520.1 - 0.024 14.5 0.7 0.32 10.8 0.0 2.4 1 1 2 3 3 3 0 Yqey-like protein DUF1103 PF06513.6 CDI79520.1 - 0.03 13.7 2.8 0.041 13.2 2.0 1.3 1 0 0 1 1 1 0 Repeat of unknown function (DUF1103) LINES_C PF14695.1 CDI79520.1 - 0.053 12.7 0.0 0.097 11.9 0.0 1.4 1 0 0 1 1 1 0 Lines C-terminus RNA_pol_Rpb4 PF03874.11 CDI79520.1 - 0.055 13.4 2.2 3.2 7.7 0.1 2.6 3 0 0 3 3 2 0 RNA polymerase Rpb4 DUF853 PF05872.7 CDI79520.1 - 0.058 11.7 0.1 1.1 7.5 0.0 2.0 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF853) Toprim_2 PF13155.1 CDI79520.1 - 0.11 12.8 0.4 3.7 7.9 0.2 2.4 1 1 0 1 1 1 0 Toprim-like Ribosomal_S10 PF00338.17 CDI79521.1 - 3.6e-29 100.4 0.1 4.1e-29 100.2 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e DUF1922 PF09082.5 CDI79521.1 - 0.011 15.7 0.3 0.026 14.5 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1922) Ribosomal_L35Ae PF01247.13 CDI79522.1 - 4.8e-43 144.8 0.6 5.9e-43 144.5 0.4 1.1 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.13 CDI79522.1 - 0.024 14.5 0.1 7.8 6.4 0.0 2.2 2 0 0 2 2 2 0 RimM N-terminal domain OMPdecase PF00215.19 CDI79523.1 - 2e-24 86.2 0.0 5.3e-24 84.8 0.0 1.6 1 1 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family DHDPS PF00701.17 CDI79523.1 - 0.11 11.0 0.2 0.96 7.9 0.0 2.3 3 0 0 3 3 3 0 Dihydrodipicolinate synthetase family HEAT PF02985.17 CDI79526.1 - 2.6e-09 36.3 16.4 0.52 10.5 0.0 8.5 9 0 0 9 9 9 4 HEAT repeat HEAT_2 PF13646.1 CDI79526.1 - 6.5e-08 32.7 22.8 0.047 13.9 0.3 7.2 5 3 1 7 7 7 4 HEAT repeats HEAT_EZ PF13513.1 CDI79526.1 - 8.1e-08 32.5 0.7 8.1e-08 32.5 0.5 8.4 7 1 2 9 9 9 1 HEAT-like repeat IBN_N PF03810.14 CDI79526.1 - 3.1e-05 23.7 0.1 3.1e-05 23.7 0.1 3.3 4 0 0 4 4 4 1 Importin-beta N-terminal domain Herpes_IE68 PF02479.11 CDI79526.1 - 0.054 12.7 0.0 0.12 11.5 0.0 1.6 1 0 0 1 1 1 0 Herpesvirus immediate early protein PEARLI-4 PF05278.7 CDI79526.1 - 0.11 11.9 0.2 0.49 9.7 0.1 2.0 2 0 0 2 2 2 0 Arabidopsis phospholipase-like protein (PEARLI 4) Cohesin_HEAT PF12765.2 CDI79526.1 - 1.6 8.8 7.4 32 4.6 0.1 4.1 3 0 0 3 3 3 0 HEAT repeat associated with sister chromatid cohesion Proteasome PF00227.21 CDI79528.1 - 7.5e-59 198.2 0.0 9.1e-59 197.9 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 CDI79528.1 - 1.5e-14 52.9 0.4 2.5e-14 52.2 0.2 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature GM_CSF PF01109.12 CDI79528.1 - 0.0092 15.9 0.2 0.022 14.6 0.0 1.7 2 0 0 2 2 2 1 Granulocyte-macrophage colony-stimulating factor DSPc PF00782.15 CDI79531.1 - 3e-26 91.5 0.0 4.6e-26 90.9 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.1 CDI79531.1 - 0.0015 18.5 0.1 0.0033 17.4 0.0 1.5 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase PF00102.22 CDI79531.1 - 0.0018 17.6 0.0 0.0028 17.0 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DUF1573 PF07610.6 CDI79532.1 - 0.045 13.3 0.0 0.086 12.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1573) Sec1 PF00995.18 CDI79534.1 - 9.4e-87 291.9 0.3 1.1e-65 222.4 0.0 2.2 1 1 1 2 2 2 2 Sec1 family YlbD_coat PF14071.1 CDI79534.1 - 0.0054 16.7 0.3 0.061 13.3 0.2 2.2 2 0 0 2 2 2 1 Putative coat protein SEO_C PF14577.1 CDI79534.1 - 0.009 15.4 0.3 0.023 14.0 0.2 1.6 2 0 0 2 2 2 1 Sieve element occlusion C-terminus Dor1 PF04124.7 CDI79536.1 - 1.3e-10 40.3 0.1 7.9e-07 27.8 0.0 2.4 2 0 0 2 2 2 2 Dor1-like family PK PF00224.16 CDI79538.1 - 6.5e-145 482.1 0.7 9.2e-145 481.6 0.5 1.2 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.11 CDI79538.1 - 6.5e-33 112.7 1.1 5.6e-32 109.7 0.5 2.5 2 0 0 2 2 2 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.9 CDI79538.1 - 0.00028 19.8 0.2 0.001 18.0 0.1 2.0 2 1 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family Vps8 PF12816.2 CDI79538.1 - 0.08 12.1 0.1 0.14 11.3 0.1 1.3 1 0 0 1 1 1 0 Golgi CORVET complex core vacuolar protein 8 JAB PF01398.16 CDI79540.1 - 6.5e-26 90.3 0.3 4.1e-25 87.7 0.2 2.1 1 1 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.1 CDI79540.1 - 1.3e-07 31.0 0.0 5.6e-07 29.0 0.0 2.1 1 1 0 1 1 1 1 Prokaryotic homologs of the JAB domain UPF0172 PF03665.8 CDI79540.1 - 0.00093 18.7 0.0 0.0018 17.8 0.0 1.5 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0172) Sporozoite_P67 PF05642.6 CDI79543.1 - 4.3e-05 21.6 10.2 4.3e-05 21.6 7.1 8.3 2 1 1 5 5 5 1 Sporozoite P67 surface antigen SR-25 PF10500.4 CDI79543.1 - 0.0027 17.2 19.6 0.0027 17.2 13.6 15.0 8 6 6 14 14 14 3 Nuclear RNA-splicing-associated protein Autophagy_N PF03986.8 CDI79544.1 - 2.8e-31 108.2 0.0 4.2e-31 107.6 0.0 1.2 1 0 0 1 1 1 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_act_C PF03987.10 CDI79544.1 - 3.5e-28 97.5 0.2 5.6e-28 96.8 0.1 1.3 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain DUF3123 PF11321.3 CDI79544.1 - 2.4 8.4 6.1 5.5 7.3 4.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3123) Myc_N PF01056.13 CDI79546.1 - 0.043 12.9 5.7 0.06 12.5 4.0 1.2 1 0 0 1 1 1 0 Myc amino-terminal region Apis_Csd PF11671.3 CDI79546.1 - 0.12 12.1 15.1 0.053 13.3 8.8 1.7 2 0 0 2 2 2 0 Complementary sex determiner protein TFIIA PF03153.8 CDI79546.1 - 4.2 7.1 9.5 5.4 6.8 6.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Daxx PF03344.10 CDI79568.1 - 0.00034 19.2 29.9 0.00052 18.6 20.7 1.3 1 0 0 1 1 1 1 Daxx Family PLRV_ORF5 PF01690.12 CDI79578.1 - 9.5 5.2 20.8 16 4.5 14.4 1.3 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein CobT PF06213.7 CDI79586.1 - 0.38 9.8 16.2 0.017 14.2 4.3 2.1 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT Ycf1 PF05758.7 CDI79586.1 - 0.65 7.6 21.2 0.84 7.2 14.7 1.1 1 0 0 1 1 1 0 Ycf1 Rtf2 PF04641.7 CDI79586.1 - 1.8 7.7 20.5 2.7 7.1 14.2 1.3 1 0 0 1 1 1 0 Rtf2 RING-finger Hid1 PF12722.2 CDI79586.1 - 5.7 4.4 27.6 6.8 4.2 19.1 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein YqfQ PF14181.1 CDI79586.1 - 8 6.4 28.3 2.9 7.9 10.4 2.1 2 0 0 2 2 2 0 YqfQ-like protein DUF4613 PF15390.1 CDI79586.1 - 8.5 4.4 18.8 9.5 4.2 13.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) Herpes_UL87 PF03043.9 CDI79586.1 - 8.8 4.5 13.5 11 4.2 9.4 1.1 1 0 0 1 1 1 0 Herpesvirus UL87 family Claudin_2 PF13903.1 CDI79591.1 - 0.017 14.8 6.1 0.017 14.8 4.2 2.6 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction Neur_chan_memb PF02932.11 CDI79591.1 - 0.058 13.2 9.8 0.077 12.8 6.8 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Tetraspannin PF00335.15 CDI79591.1 - 0.11 11.7 0.9 0.46 9.7 0.4 1.9 1 1 1 2 2 2 0 Tetraspanin family EphA2_TM PF14575.1 CDI79591.1 - 0.13 12.6 7.0 1.4 9.3 1.6 2.6 2 1 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain PAT1 PF09770.4 CDI79591.1 - 0.25 9.5 37.2 0.27 9.4 25.8 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 CD20 PF04103.10 CDI79591.1 - 0.25 11.2 3.3 2.8 7.8 0.5 2.3 2 0 0 2 2 2 0 CD20-like family FimP PF09766.4 CDI79591.1 - 0.38 9.7 26.0 0.15 11.0 3.9 2.0 2 0 0 2 2 2 0 Fms-interacting protein APC_CDC26 PF10471.4 CDI79591.1 - 0.45 11.2 30.3 0.6 10.8 6.9 2.6 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit 1 DUF3439 PF11921.3 CDI79591.1 - 0.73 9.5 17.0 1.3 8.7 4.7 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) DUF1764 PF08576.5 CDI79591.1 - 0.75 10.6 16.9 3.4 8.5 2.8 2.3 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF1764) Choline_transpo PF04515.7 CDI79591.1 - 1.3 7.6 5.3 15 4.2 2.9 2.2 1 1 0 1 1 1 0 Plasma-membrane choline transporter Hid1 PF12722.2 CDI79591.1 - 1.9 6.0 18.4 2.2 5.8 12.7 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF4355 PF14265.1 CDI79591.1 - 2.4 8.1 26.0 3.1 7.7 5.7 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4355) Bud13 PF09736.4 CDI79591.1 - 2.4 8.3 20.3 3.3 7.9 5.0 2.1 2 0 0 2 2 2 0 Pre-mRNA-splicing factor of RES complex PLRV_ORF5 PF01690.12 CDI79591.1 - 3.3 6.7 21.2 3.9 6.5 14.7 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein DUF4094 PF13334.1 CDI79591.1 - 3.3 8.1 11.3 1.4 9.3 0.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4094) DUF966 PF06136.8 CDI79591.1 - 3.7 6.8 23.3 6.1 6.1 16.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Utp14 PF04615.8 CDI79591.1 - 4.5 5.3 24.9 5.2 5.1 17.3 1.0 1 0 0 1 1 1 0 Utp14 protein Apt1 PF10351.4 CDI79591.1 - 4.8 5.9 9.6 6.5 5.4 6.7 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Conotoxin PF02950.12 CDI79591.1 - 5 7.9 15.2 1.2 9.9 2.0 2.6 2 0 0 2 2 2 0 Conotoxin Daxx PF03344.10 CDI79591.1 - 6.7 5.0 19.9 9.4 4.5 13.8 1.3 1 0 0 1 1 1 0 Daxx Family DUF4199 PF13858.1 CDI79591.1 - 7 6.5 17.8 0.26 11.1 3.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4199) DDRGK PF09756.4 CDI79591.1 - 7 6.0 19.5 6.5 6.1 3.7 2.1 2 0 0 2 2 2 0 DDRGK domain zf-DHHC PF01529.15 CDI79591.1 - 8.3 5.7 10.3 3.6 6.9 1.9 2.1 2 0 0 2 2 2 0 DHHC palmitoyltransferase Gryzun PF07919.7 CDI79591.1 - 8.7 4.5 13.2 3.8 5.7 1.6 2.0 2 0 0 2 2 2 0 Gryzun, putative trafficking through Golgi Agouti PF05039.7 CDI79591.1 - 9 6.7 13.9 7.1 7.0 2.4 2.2 2 0 0 2 2 2 0 Agouti protein Spc7_N PF15402.1 CDI79591.1 - 9.8 4.0 31.5 12 3.8 21.8 1.0 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 SR-25 PF10500.4 CDI79607.1 - 0.0022 17.4 14.5 0.0022 17.4 10.0 4.2 3 1 0 4 4 4 2 Nuclear RNA-splicing-associated protein DUF4557 PF15101.1 CDI79607.1 - 0.0059 16.4 8.1 0.0059 16.4 5.6 5.8 2 1 3 6 6 6 1 Domain of unknown function (DUF4557) Suf PF05843.9 CDI79656.1 - 0.45 10.1 9.7 0.64 9.6 6.7 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Senescence_reg PF04520.8 CDI79656.1 - 1.6 9.1 7.7 2.1 8.7 5.4 1.1 1 0 0 1 1 1 0 Senescence regulator DUF4483 PF14825.1 CDI79656.1 - 1.8 8.2 11.4 0.034 13.8 1.3 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4483) Spore_coat_CotO PF14153.1 CDI79656.1 - 2.5 7.4 8.5 3.4 7.0 5.9 1.3 1 0 0 1 1 1 0 Spore coat protein CotO DUF4629 PF15442.1 CDI79656.1 - 2.6 8.1 12.0 3.6 7.6 8.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4629) Med15 PF09606.5 CDI79656.1 - 4 5.5 28.6 4.7 5.2 19.8 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Tetraspannin PF00335.15 CDI79656.1 - 6 6.0 6.3 10 5.3 4.4 1.4 1 1 0 1 1 1 0 Tetraspanin family TFIIA PF03153.8 CDI79656.1 - 8.1 6.2 19.6 11 5.8 13.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PAT1 PF09770.4 CDI79656.1 - 8.7 4.4 23.7 10 4.2 16.4 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TMEM51 PF15345.1 CDI79656.1 - 9.9 5.7 12.1 12 5.5 8.4 1.1 1 0 0 1 1 1 0 Transmembrane protein 51 AIF_C PF14721.1 CDI79660.1 - 8.5e-05 22.8 7.1 8.5e-05 22.8 4.9 2.1 1 1 1 2 2 2 1 Apoptosis-inducing factor, mitochondrion-associated, C-term DUF4175 PF13779.1 CDI79660.1 - 0.002 15.9 26.5 0.002 15.9 18.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4175) DUF4604 PF15377.1 CDI79660.1 - 0.0034 17.6 19.5 0.0044 17.2 13.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4604) Med15 PF09606.5 CDI79660.1 - 0.0068 14.6 32.5 0.0074 14.5 22.5 1.2 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal FCP1_C PF09309.5 CDI79660.1 - 0.016 14.5 20.1 0.023 14.0 14.0 1.2 1 0 0 1 1 1 0 FCP1, C-terminal Plasmodium_Vir PF05795.6 CDI79660.1 - 0.021 14.0 10.6 0.024 13.8 7.4 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Nucleo_P87 PF07267.6 CDI79660.1 - 0.046 12.4 16.8 0.052 12.2 11.6 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 VKG_Carbox PF05090.9 CDI79660.1 - 0.061 12.1 0.8 0.079 11.8 0.6 1.1 1 0 0 1 1 1 0 Vitamin K-dependent gamma-carboxylase Ndc1_Nup PF09531.5 CDI79660.1 - 0.12 10.8 21.3 0.12 10.7 14.8 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF3347 PF11827.3 CDI79660.1 - 0.21 11.6 22.5 0.26 11.2 15.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3347) DNA_pol_viral_N PF00242.12 CDI79660.1 - 0.24 10.3 22.9 0.29 10.1 15.9 1.0 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain Spc7_N PF15402.1 CDI79660.1 - 0.26 9.2 23.6 0.28 9.1 16.4 1.0 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 TFIIF_alpha PF05793.7 CDI79660.1 - 0.54 8.5 22.7 0.71 8.1 15.7 1.0 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Herpes_UL87 PF03043.9 CDI79660.1 - 0.59 8.4 13.2 0.67 8.2 9.2 1.1 1 0 0 1 1 1 0 Herpesvirus UL87 family SID-1_RNA_chan PF13965.1 CDI79660.1 - 0.6 8.2 8.9 0.72 7.9 6.2 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Oleosin PF01277.12 CDI79660.1 - 0.71 9.4 5.3 0.31 10.6 1.7 1.8 1 1 0 2 2 2 0 Oleosin DUF3357 PF11837.3 CDI79660.1 - 1.1 9.1 10.6 8.9 6.2 1.2 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF3357) Paf1 PF03985.8 CDI79660.1 - 1.2 7.7 24.1 0.0084 14.8 7.7 2.0 2 0 0 2 2 2 0 Paf1 SeqA PF03925.8 CDI79660.1 - 1.2 8.7 19.8 0.044 13.4 8.1 1.9 1 1 1 2 2 2 0 SeqA protein FHIPEP PF00771.15 CDI79660.1 - 1.2 7.3 6.4 1.3 7.2 4.5 1.3 1 0 0 1 1 1 0 FHIPEP family DUF106 PF01956.11 CDI79660.1 - 1.3 8.5 12.5 2 7.9 8.6 1.4 1 1 0 1 1 1 0 Integral membrane protein DUF106 SRP-alpha_N PF04086.8 CDI79660.1 - 1.4 8.2 24.3 1.9 7.8 16.9 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal DUF2615 PF11027.3 CDI79660.1 - 1.4 8.8 11.7 0.6 10.0 5.7 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2615) DUF4106 PF13388.1 CDI79660.1 - 2 7.3 19.7 2.3 7.0 13.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) YqfQ PF14181.1 CDI79660.1 - 2.2 8.3 23.9 0.86 9.6 10.1 2.1 2 0 0 2 2 2 0 YqfQ-like protein PBP1_TM PF14812.1 CDI79660.1 - 2.3 8.6 12.5 0.29 11.4 5.1 2.0 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Hid1 PF12722.2 CDI79660.1 - 2.7 5.5 27.9 3.4 5.2 19.3 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein PAT1 PF09770.4 CDI79660.1 - 3 5.9 33.1 4.1 5.5 23.0 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Secretin_N_2 PF07655.8 CDI79660.1 - 4.1 7.8 27.9 2.6 8.4 10.6 2.8 3 0 0 3 3 3 0 Secretin N-terminal domain SUZ PF12752.2 CDI79660.1 - 5 7.7 16.4 3.6e+03 -1.5 11.3 2.6 1 1 0 1 1 1 0 SUZ domain Neur_chan_memb PF02932.11 CDI79660.1 - 5.8 6.7 15.6 8.3 6.2 10.8 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region YfhO PF09586.5 CDI79660.1 - 6.5 4.6 15.5 6.7 4.5 10.8 1.1 1 0 0 1 1 1 0 Bacterial membrane protein YfhO FAM60A PF15396.1 CDI79660.1 - 7.1 6.3 21.4 11 5.6 14.8 1.3 1 0 0 1 1 1 0 Protein Family FAM60A DUF1754 PF08555.5 CDI79660.1 - 7.2 7.2 23.5 8.3 7.0 9.2 2.2 2 0 0 2 2 2 0 Eukaryotic family of unknown function (DUF1754) DUF605 PF04652.11 CDI79664.1 - 1.6 8.0 15.9 2.1 7.6 11.0 1.1 1 0 0 1 1 1 0 Vta1 like PAP1 PF08601.5 CDI79664.1 - 1.8 8.1 21.8 2.4 7.7 15.1 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 Apc15p PF05841.6 CDI79664.1 - 2.5 8.8 11.2 4.9 7.9 7.8 1.5 1 0 0 1 1 1 0 Apc15p protein DUF2217 PF10265.4 CDI79664.1 - 8 5.0 13.8 11 4.5 9.6 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) ABC_ATPase PF09818.4 CDI79709.1 - 4.8e-78 262.7 1.0 2.9e-77 260.1 0.7 1.9 1 1 0 1 1 1 1 Predicted ATPase of the ABC class AAA_23 PF13476.1 CDI79709.1 - 0.0013 19.1 0.1 0.0015 18.9 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.1 CDI79709.1 - 0.047 13.2 0.0 0.13 11.7 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_25 PF13481.1 CDI79709.1 - 0.14 11.5 0.0 0.23 10.8 0.0 1.4 1 1 0 1 1 1 0 AAA domain FimP PF09766.4 CDI79729.1 - 0.009 15.1 4.7 0.009 15.1 3.3 2.2 2 0 0 2 2 2 1 Fms-interacting protein DUF3801 PF12687.2 CDI79729.1 - 0.022 14.3 11.2 0.066 12.7 8.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3801) U1snRNP70_N PF12220.3 CDI79729.1 - 0.32 11.3 13.3 0.75 10.1 0.7 2.3 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal DUF1168 PF06658.7 CDI79729.1 - 0.33 10.4 26.2 0.04 13.4 5.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1168) Pox_Ag35 PF03286.9 CDI79729.1 - 0.56 9.7 15.3 0.31 10.5 4.2 2.2 2 0 0 2 2 2 0 Pox virus Ag35 surface protein MAT1 PF06391.8 CDI79729.1 - 1.6 8.2 19.4 1.6 8.2 0.5 2.1 2 0 0 2 2 2 0 CDK-activating kinase assembly factor MAT1 Suf PF05843.9 CDI79740.1 - 1.6 8.3 0.0 1.6 8.3 0.0 5.9 3 1 1 4 4 4 0 Suppressor of forked protein (Suf) Synaptobrevin PF00957.16 CDI79746.1 - 2.2 7.9 3.7 24 4.5 0.1 2.4 2 0 0 2 2 2 0 Synaptobrevin PAT1 PF09770.4 CDI79748.1 - 0.0007 17.9 25.0 0.0007 17.9 17.4 7.4 6 1 0 7 7 7 3 Topoisomerase II-associated protein PAT1 Pex14_N PF04695.8 CDI79748.1 - 0.0057 16.6 11.7 0.0057 16.6 8.1 17.7 10 4 5 16 16 16 3 Peroxisomal membrane anchor protein (Pex14p) conserved region WD40 PF00400.27 CDI79748.1 - 0.012 15.5 0.0 0.012 15.5 0.0 2.8 3 0 0 3 3 3 0 WD domain, G-beta repeat RskA PF10099.4 CDI79749.1 - 0.075 12.7 18.1 0.096 12.4 12.6 1.2 1 0 0 1 1 1 0 Anti-sigma-K factor rskA Trp_oprn_chp PF09534.5 CDI79749.1 - 0.18 11.3 12.1 0.18 11.3 8.4 1.0 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF4366 PF14283.1 CDI79749.1 - 0.24 10.8 12.7 0.28 10.5 8.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) DUF4259 PF14078.1 CDI79749.1 - 5.3 7.5 10.6 6.7 7.2 7.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4259) Lipoprotein_2 PF00921.12 CDI79749.1 - 6.7 6.6 16.9 7.8 6.4 11.7 1.1 1 0 0 1 1 1 0 Borrelia lipoprotein Nop14 PF04147.7 CDI79752.1 - 1.3 6.8 21.5 1.5 6.6 14.9 1.1 1 0 0 1 1 1 0 Nop14-like family DNA_pol3_a_NII PF11490.3 CDI79752.1 - 2.3 7.8 18.7 4.3 6.9 13.0 1.4 1 0 0 1 1 1 0 DNA polymerase III polC-type N-terminus II DUF4647 PF15504.1 CDI79752.1 - 2.3 6.9 25.8 2.7 6.7 17.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4647) DUF572 PF04502.8 CDI79752.1 - 3 6.9 42.4 4 6.5 29.4 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) Utp14 PF04615.8 CDI79752.1 - 6 4.8 37.7 7.5 4.5 26.1 1.1 1 0 0 1 1 1 0 Utp14 protein Hid1 PF12722.2 CDI79752.1 - 6.4 4.3 40.2 7.5 4.1 27.8 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein RAB3GAP2_N PF14655.1 CDI79804.1 - 0.31 9.9 10.7 0.37 9.7 7.0 1.4 1 1 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus PAT1 PF09770.4 CDI79804.1 - 1.9 6.6 26.1 2.1 6.4 18.1 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TFIIA PF03153.8 CDI79804.1 - 2.1 8.1 29.9 2.8 7.7 20.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Peptidase_S15 PF02129.13 CDI79804.1 - 9.5 5.5 12.4 2.9 7.2 6.7 1.5 1 1 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) HABP4_PAI-RBP1 PF04774.10 CDI79808.1 - 2.9e-17 63.0 13.6 2.9e-17 63.0 9.4 3.3 2 1 1 3 3 3 1 Hyaluronan / mRNA binding family Med15 PF09606.5 CDI79808.1 - 0.46 8.6 31.6 0.58 8.3 21.9 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Spt20 PF12090.3 CDI79808.1 - 0.86 8.9 7.6 2.2 7.5 5.3 1.7 1 0 0 1 1 1 0 Spt20 family CD20 PF04103.10 CDI79811.1 - 0.3 10.9 0.0 0.3 10.9 0.0 3.5 3 1 0 3 3 3 0 CD20-like family HhH-GPD PF00730.20 CDI79824.1 - 2.2e-06 27.9 0.0 2.4e-06 27.7 0.0 1.1 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein DUF2400 PF09674.5 CDI79824.1 - 0.14 11.8 0.0 0.14 11.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) RNA_pol_A_CTD PF03118.10 CDI79825.1 - 8e-05 21.9 0.0 0.00015 21.0 0.0 1.6 1 0 0 1 1 1 1 Bacterial RNA polymerase, alpha chain C terminal domain SDA1 PF05285.7 CDI79825.1 - 0.0015 17.8 8.6 0.0015 17.8 5.9 1.1 1 0 0 1 1 1 1 SDA1 CDC45 PF02724.9 CDI79825.1 - 0.0035 15.4 9.5 0.003 15.6 6.6 1.1 1 0 0 1 1 1 1 CDC45-like protein Spore_coat_CotO PF14153.1 CDI79825.1 - 0.0075 15.7 17.6 0.0075 15.7 12.2 1.1 1 0 0 1 1 1 1 Spore coat protein CotO Pex14_N PF04695.8 CDI79825.1 - 0.017 15.1 8.8 0.018 15.1 6.1 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region GIDA_assoc_3 PF13932.1 CDI79825.1 - 0.025 14.6 0.7 0.025 14.6 0.5 3.1 1 1 1 2 2 1 0 GidA associated domain 3 HHH_5 PF14520.1 CDI79825.1 - 0.031 14.4 0.0 0.046 13.8 0.0 1.3 1 0 0 1 1 1 0 Helix-hairpin-helix domain UPF0560 PF10577.4 CDI79825.1 - 0.064 11.5 18.0 0.062 11.5 12.5 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Ycf1 PF05758.7 CDI79825.1 - 0.067 10.8 11.8 0.056 11.1 8.2 1.0 1 0 0 1 1 1 0 Ycf1 SAPS PF04499.10 CDI79825.1 - 0.07 11.7 8.7 0.06 11.9 6.0 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein SPX PF03105.14 CDI79825.1 - 0.11 12.2 8.1 0.1 12.3 5.6 1.1 1 0 0 1 1 1 0 SPX domain SpoVR PF04293.8 CDI79825.1 - 0.11 10.8 8.4 0.1 10.9 5.8 1.1 1 0 0 1 1 1 0 SpoVR like protein Med15 PF09606.5 CDI79825.1 - 0.15 10.2 35.2 0.13 10.4 24.4 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Presenilin PF01080.12 CDI79825.1 - 0.18 10.5 5.3 0.17 10.6 3.6 1.1 1 0 0 1 1 1 0 Presenilin eIF-3_zeta PF05091.7 CDI79825.1 - 0.2 10.2 12.1 0.2 10.2 8.4 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) LMBR1 PF04791.11 CDI79825.1 - 0.38 9.2 3.0 0.4 9.2 2.1 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF506 PF04720.7 CDI79825.1 - 0.42 10.2 5.7 0.42 10.2 3.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF506) TT_ORF1 PF02956.9 CDI79825.1 - 0.43 8.9 4.4 0.39 9.1 3.1 1.0 1 0 0 1 1 1 0 TT viral orf 1 Spore_YhcN_YlaJ PF09580.5 CDI79825.1 - 0.57 10.2 13.0 0.73 9.9 9.0 1.1 1 0 0 1 1 1 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) DUF4011 PF13195.1 CDI79825.1 - 0.63 10.0 7.6 0.66 9.9 5.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4011) RP-C_C PF11800.3 CDI79825.1 - 1.2 8.7 10.7 1.4 8.5 7.4 1.2 1 0 0 1 1 1 0 Replication protein C C-terminal region CDK5_activator PF03261.10 CDI79825.1 - 1.5 8.0 10.0 1.6 8.0 7.0 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein Ndc1_Nup PF09531.5 CDI79825.1 - 1.6 7.0 5.5 1.4 7.2 3.8 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Dynamin_N PF00350.18 CDI79825.1 - 1.6 8.5 5.2 1.9 8.2 3.6 1.3 1 0 0 1 1 1 0 Dynamin family Peptidase_S64 PF08192.6 CDI79825.1 - 1.6 6.9 8.0 1.7 6.8 5.6 1.0 1 0 0 1 1 1 0 Peptidase family S64 DHHW PF14286.1 CDI79825.1 - 1.8 7.8 10.8 1.7 7.8 7.5 1.1 1 0 0 1 1 1 0 DHHW protein SelP_N PF04592.9 CDI79825.1 - 2.6 7.3 18.1 3.1 7.1 12.6 1.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region PAT1 PF09770.4 CDI79825.1 - 2.7 6.1 29.9 2.8 6.0 20.7 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Borrelia_P83 PF05262.6 CDI79825.1 - 4.5 5.4 17.5 4.5 5.4 12.2 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF4175 PF13779.1 CDI79825.1 - 5.2 4.6 41.0 6.4 4.3 28.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) YqfQ PF14181.1 CDI79825.1 - 5.7 6.9 20.9 7.4 6.5 14.5 1.1 1 0 0 1 1 1 0 YqfQ-like protein FHIPEP PF00771.15 CDI79825.1 - 6.2 5.0 6.9 6.7 4.9 4.8 1.2 1 0 0 1 1 1 0 FHIPEP family Gti1_Pac2 PF09729.4 CDI79825.1 - 6.4 6.6 11.3 8.1 6.2 7.8 1.1 1 0 0 1 1 1 0 Gti1/Pac2 family Tim54 PF11711.3 CDI79825.1 - 6.7 5.2 13.9 7.4 5.0 9.6 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DUF4407 PF14362.1 CDI79825.1 - 7.7 5.3 17.5 9.8 5.0 12.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) OATP PF03137.15 CDI79825.1 - 8.1 4.3 7.7 10 4.0 5.3 1.3 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family DUF1454 PF07305.7 CDI79841.1 - 0.99 8.4 8.9 0.057 12.5 1.2 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1454) Spore_YhcN_YlaJ PF09580.5 CDI79841.1 - 9.9 6.2 10.8 1.2 9.2 0.2 3.1 3 0 0 3 3 3 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) PAT1 PF09770.4 CDI79877.1 - 0.18 10.0 92.0 0.18 9.9 63.8 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Spt20 PF12090.3 CDI79883.1 - 0.0015 17.9 3.4 0.0016 17.7 2.4 1.1 1 0 0 1 1 1 1 Spt20 family Pol_alpha_B_N PF08418.5 CDI79883.1 - 0.061 12.8 8.0 0.075 12.5 5.5 1.1 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal Band_3_cyto PF07565.8 CDI79883.1 - 0.064 12.7 3.1 0.08 12.4 2.1 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Allexi_40kDa PF05549.6 CDI79883.1 - 0.26 10.5 5.3 0.33 10.1 3.7 1.1 1 0 0 1 1 1 0 Allexivirus 40kDa protein PIH1 PF08190.7 CDI79883.1 - 0.75 9.1 9.1 1 8.7 6.3 1.1 1 0 0 1 1 1 0 pre-RNA processing PIH1/Nop17 PAT1 PF09770.4 CDI79883.1 - 0.79 7.8 17.6 0.88 7.7 12.2 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Hamartin PF04388.7 CDI79883.1 - 0.96 8.0 8.8 1.1 7.8 6.1 1.1 1 0 0 1 1 1 0 Hamartin protein Macoilin PF09726.4 CDI79883.1 - 0.98 7.6 8.4 1.2 7.3 5.9 1.1 1 0 0 1 1 1 0 Transmembrane protein EIIBC-GUT_N PF03612.9 CDI79883.1 - 5.5 6.5 6.9 13 5.3 4.8 1.6 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus FimP PF09766.4 CDI79883.1 - 6.3 5.7 15.9 8 5.4 11.0 1.1 1 0 0 1 1 1 0 Fms-interacting protein DivIC PF04977.10 CDI79883.1 - 7.4 6.1 14.4 13 5.3 10.0 1.4 1 0 0 1 1 1 0 Septum formation initiator DUF4557 PF15101.1 CDI79883.1 - 9.6 5.9 15.7 15 5.3 10.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) PT PF04886.7 CDI79891.1 - 1.4e-07 30.6 28.9 0.00032 19.9 1.2 4.7 3 2 0 3 3 3 3 PT repeat Ribosomal_60s PF00428.14 CDI79891.1 - 0.0076 16.6 24.4 0.073 13.4 12.8 2.8 2 0 0 2 2 2 2 60s Acidic ribosomal protein SOG2 PF10428.4 CDI79891.1 - 0.26 9.8 29.6 0.064 11.9 15.1 2.4 2 0 0 2 2 2 0 RAM signalling pathway protein Rifin_STEVOR PF02009.11 CDI79891.1 - 6.1 6.3 6.8 13 5.2 4.7 1.5 1 0 0 1 1 1 0 Rifin/stevor family RskA PF10099.4 CDI79906.1 - 0.0031 17.2 4.2 0.0033 17.1 2.9 1.2 1 0 0 1 1 1 1 Anti-sigma-K factor rskA DUF4207 PF13904.1 CDI79906.1 - 0.0051 16.2 29.4 0.0075 15.6 20.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4207) PTPlike_phytase PF14566.1 CDI79906.1 - 0.044 13.8 2.6 0.048 13.7 1.8 1.2 1 0 0 1 1 1 0 Inositol hexakisphosphate Med15 PF09606.5 CDI79906.1 - 0.15 10.2 30.5 0.18 9.9 21.2 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Trp_oprn_chp PF09534.5 CDI79906.1 - 0.17 11.4 6.0 0.2 11.2 4.2 1.2 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) SprA-related PF12118.3 CDI79906.1 - 0.34 10.1 42.8 0.46 9.7 29.7 1.1 1 0 0 1 1 1 0 SprA-related family bZIP_C PF12498.3 CDI79906.1 - 0.49 11.6 23.9 0.64 11.2 16.6 1.1 1 0 0 1 1 1 0 Basic leucine-zipper C terminal DUF2413 PF10310.4 CDI79906.1 - 0.57 8.9 32.3 0.71 8.6 22.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) Suf PF05843.9 CDI79906.1 - 0.59 9.8 22.6 0.77 9.4 15.7 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Corona_nucleoca PF00937.13 CDI79906.1 - 0.7 8.7 33.9 1 8.2 23.5 1.2 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein BaxI_1 PF12811.2 CDI79906.1 - 0.87 8.6 8.1 1 8.4 5.6 1.2 1 0 0 1 1 1 0 Bax inhibitor 1 like DUF3457 PF11939.3 CDI79906.1 - 1 8.8 8.1 1.1 8.7 5.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3457) DUF4358 PF14270.1 CDI79906.1 - 1.1 9.1 10.2 1.1 9.2 6.4 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4358) ICAP-1_inte_bdg PF10480.4 CDI79906.1 - 1.4 8.6 17.8 1.7 8.3 12.3 1.1 1 0 0 1 1 1 0 Beta-1 integrin binding protein ACC_epsilon PF13822.1 CDI79906.1 - 1.6 9.1 6.8 7.6 6.9 4.7 2.1 1 1 0 1 1 1 0 Acyl-CoA carboxylase epsilon subunit NAM-associated PF14303.1 CDI79906.1 - 1.8 8.8 20.8 2.6 8.3 14.4 1.3 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain PepSY_2 PF13670.1 CDI79906.1 - 1.8 8.5 7.5 2.7 7.9 5.2 1.2 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain SR-25 PF10500.4 CDI79906.1 - 2.1 7.7 51.6 0.17 11.3 14.3 2.0 1 1 1 2 2 2 0 Nuclear RNA-splicing-associated protein DUF605 PF04652.11 CDI79906.1 - 2.3 7.5 30.3 2.7 7.3 21.0 1.0 1 0 0 1 1 1 0 Vta1 like DUF572 PF04502.8 CDI79906.1 - 3.4 6.8 28.4 3.9 6.6 19.7 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF3807 PF12720.2 CDI79906.1 - 4.1 7.5 24.6 5.1 7.2 17.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) RR_TM4-6 PF06459.7 CDI79906.1 - 4.9 6.9 16.0 5.7 6.7 11.1 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Ald_Xan_dh_C2 PF02738.13 CDI79906.1 - 5.2 5.2 12.4 2.1 6.5 7.3 1.2 1 1 0 1 1 1 0 Molybdopterin-binding domain of aldehyde dehydrogenase TFIIA PF03153.8 CDI79906.1 - 5.4 6.8 34.6 6.8 6.4 24.0 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF2201_N PF13203.1 CDI79906.1 - 6.3 5.8 24.1 7.3 5.6 16.7 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain Utp14 PF04615.8 CDI79906.1 - 8 4.4 26.4 9.1 4.3 18.3 1.0 1 0 0 1 1 1 0 Utp14 protein DUF3154 PF11351.3 CDI79906.1 - 8.6 6.1 10.9 15 5.3 7.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3154) DUF3801 PF12687.2 CDI79906.1 - 8.8 5.8 18.4 12 5.4 12.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3801) DUF1675 PF07897.6 CDI79906.1 - 8.9 6.0 30.6 10 5.9 21.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) RAP1 PF07218.6 CDI79906.1 - 9.7 4.1 24.0 11 3.9 16.7 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) BNIP2 PF12496.3 CDI79906.1 - 9.9 6.3 9.8 13 6.0 6.8 1.1 1 0 0 1 1 1 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 Baculo_ODV-E27 PF05314.6 CDI79933.1 - 1.2 8.1 13.9 1.7 7.6 9.6 1.3 1 1 0 1 1 1 0 Baculovirus occlusion-derived virus envelope protein EC27 Herpes_env PF01673.13 CDI79933.1 - 9.9 4.5 24.5 11 4.4 17.0 1.0 1 0 0 1 1 1 0 Herpesvirus putative major envelope glycoprotein UPF0552 PF10574.4 CDI79944.1 - 0.013 14.9 0.1 0.013 14.9 0.1 3.6 3 1 1 5 5 5 0 Uncharacterised protein family UPF0552 PAS_6 PF08348.6 CDI79944.1 - 1.4 8.4 0.0 1.4 8.4 0.0 3.3 2 1 2 4 4 4 0 YheO-like PAS domain TPR_11 PF13414.1 CDI79964.1 - 2.6e-07 30.1 0.6 1.1e-06 28.2 0.0 2.1 2 0 0 2 2 2 1 TPR repeat BAF1_ABF1 PF04684.8 CDI79964.1 - 5.9e-05 22.1 24.1 5.9e-05 22.1 16.7 2.9 3 0 0 3 3 3 1 BAF1 / ABF1 chromatin reorganising factor TPR_2 PF07719.12 CDI79964.1 - 0.00056 19.6 0.0 0.025 14.4 0.0 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 CDI79964.1 - 0.0014 19.2 0.0 0.0014 19.2 0.0 3.5 3 0 0 3 3 2 1 Tetratricopeptide repeat Shadoo PF14999.1 CDI79964.1 - 0.0078 16.0 11.9 0.032 14.0 0.5 3.0 3 0 0 3 3 3 1 Shadow of prion protein, neuroprotective PAT1 PF09770.4 CDI79964.1 - 0.0086 14.3 46.7 0.011 13.9 32.3 1.1 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 TPR_1 PF00515.23 CDI79964.1 - 0.014 15.0 0.0 0.051 13.2 0.0 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat Med15 PF09606.5 CDI79964.1 - 0.026 12.7 58.4 0.045 11.9 40.5 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal TPR_14 PF13428.1 CDI79964.1 - 0.091 13.4 0.0 0.091 13.4 0.0 4.5 4 2 2 6 6 3 0 Tetratricopeptide repeat TPR_17 PF13431.1 CDI79964.1 - 0.14 12.4 0.0 0.14 12.4 0.0 3.0 3 1 0 3 3 1 0 Tetratricopeptide repeat MLANA PF14991.1 CDI79964.1 - 0.22 11.5 5.9 1.5 8.8 0.1 2.4 2 0 0 2 2 2 0 Protein melan-A DUF966 PF06136.8 CDI79964.1 - 0.26 10.6 17.5 0.054 12.9 8.6 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF966) FimP PF09766.4 CDI79964.1 - 0.31 10.0 27.6 2.3 7.1 0.2 2.2 2 0 0 2 2 2 0 Fms-interacting protein DUF4647 PF15504.1 CDI79964.1 - 0.81 8.4 23.0 0.098 11.4 9.7 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4647) DUF4175 PF13779.1 CDI79964.1 - 0.97 7.0 46.0 1.1 6.9 23.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4175) Herpes_LMP2 PF07415.6 CDI79964.1 - 1.9 6.9 9.0 3.1 6.2 6.2 1.4 1 0 0 1 1 1 0 Gammaherpesvirus latent membrane protein (LMP2) protein Herpes_DNAp_acc PF04929.7 CDI79964.1 - 2.3 7.1 11.2 3.3 6.5 7.8 1.3 1 0 0 1 1 1 0 Herpes DNA replication accessory factor DUF2681 PF10883.3 CDI79964.1 - 9.2 6.5 31.9 0.84 9.8 2.4 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) BSD PF03909.12 CDI79980.1 - 0.0005 19.7 0.0 0.00093 18.8 0.0 1.4 1 0 0 1 1 1 1 BSD domain DUF1424 PF07232.6 CDI79980.1 - 0.091 11.5 0.2 4.7 5.8 0.1 2.1 2 0 0 2 2 2 0 Putative rep protein (DUF1424) WD40 PF00400.27 CDI79982.1 - 1.7e-06 27.6 0.2 0.047 13.5 0.0 4.2 3 0 0 3 3 3 2 WD domain, G-beta repeat DEAD PF00270.24 CDI79986.1 - 8.1e-13 48.2 0.3 1.4e-12 47.4 0.2 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 CDI79986.1 - 0.0095 15.7 0.1 0.03 14.1 0.0 1.7 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit KH_2 PF07650.12 CDI79986.1 - 0.13 11.8 0.7 0.29 10.7 0.5 1.6 1 0 0 1 1 1 0 KH domain Ribosomal_60s PF00428.14 CDI79998.1 - 1.5 9.3 13.8 2.1 8.8 4.1 2.2 2 0 0 2 2 2 0 60s Acidic ribosomal protein Phostensin_N PF13916.1 CDI79998.1 - 2.4 8.1 10.7 6 6.9 0.6 2.4 2 0 0 2 2 2 0 PP1-regulatory protein, Phostensin N-terminal Myb_DNA-binding PF00249.26 CDI80017.1 - 5.1e-10 39.2 0.0 1.1e-09 38.2 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 CDI80017.1 - 3.2e-07 30.3 0.0 6.4e-07 29.3 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain DUF966 PF06136.8 CDI80017.1 - 0.0017 17.8 12.7 0.0021 17.5 8.8 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF966) CytochromB561_N PF09786.4 CDI80017.1 - 0.065 11.6 10.9 0.082 11.3 7.6 1.3 1 0 0 1 1 1 0 Cytochrome B561, N terminal Myb_DNA-bind_4 PF13837.1 CDI80017.1 - 0.074 13.1 0.2 0.61 10.2 0.0 2.5 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain PAP1 PF08601.5 CDI80017.1 - 0.17 11.5 18.2 0.25 11.0 12.6 1.2 1 0 0 1 1 1 0 Transcription factor PAP1 Macoilin PF09726.4 CDI80017.1 - 0.92 7.7 24.1 1.3 7.2 16.7 1.1 1 0 0 1 1 1 0 Transmembrane protein Cwf_Cwc_15 PF04889.7 CDI80017.1 - 1.7 8.2 11.2 0.19 11.3 4.5 1.8 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Peptidase_S64 PF08192.6 CDI80017.1 - 5.9 5.0 18.6 7.6 4.7 12.9 1.1 1 0 0 1 1 1 0 Peptidase family S64 Plasmodium_Vir PF05795.6 CDI80017.1 - 7.9 5.5 7.3 11 5.0 5.1 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Mcm10 PF09332.6 CDI80017.1 - 8.4 5.6 14.0 16 4.7 9.7 1.4 1 0 0 1 1 1 0 Mcm10 replication factor RRM_1 PF00076.17 CDI80030.1 - 1.8e-14 53.1 0.0 2.7e-14 52.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CDI80030.1 - 4.3e-12 45.8 0.0 6.4e-12 45.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CDI80030.1 - 3.1e-07 30.1 0.0 4.9e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PAT1 PF09770.4 CDI80035.1 - 5.2 5.1 36.3 6.4 4.8 25.2 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SR-25 PF10500.4 CDI80043.1 - 0.0084 15.6 23.8 0.0084 15.6 16.5 4.3 1 1 2 4 4 4 2 Nuclear RNA-splicing-associated protein Methyltransf_21 PF05050.7 CDI80043.1 - 1.2 9.0 5.9 16 5.3 0.1 3.2 3 0 0 3 3 3 0 Methyltransferase FkbM domain FHIPEP PF00771.15 CDI80049.1 - 0.36 9.0 14.3 0.37 9.0 9.9 1.1 1 0 0 1 1 1 0 FHIPEP family Gti1_Pac2 PF09729.4 CDI80049.1 - 2 8.2 13.2 2.2 8.1 9.1 1.1 1 0 0 1 1 1 0 Gti1/Pac2 family FYDLN_acid PF09538.5 CDI80049.1 - 2.3 8.8 7.4 2.6 8.6 5.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) SID-1_RNA_chan PF13965.1 CDI80049.1 - 5 5.1 12.0 5.1 5.1 8.3 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DUF4045 PF13254.1 CDI80049.1 - 6 6.0 17.1 5.8 6.0 11.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) FLO_LFY PF01698.11 CDI80049.1 - 6.5 5.4 17.2 6.6 5.4 11.9 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein Med15 PF09606.5 CDI80050.1 - 0.067 11.3 74.9 0.082 11.1 51.9 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal MAP7 PF05672.6 CDI80050.1 - 0.33 10.3 30.7 0.47 9.8 21.3 1.1 1 0 0 1 1 1 0 MAP7 (E-MAP-115) family DUF3552 PF12072.3 CDI80050.1 - 0.57 9.3 33.7 0.63 9.2 23.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) Activator_LAG-3 PF11498.3 CDI80050.1 - 1.2 7.8 76.5 1.3 7.7 53.0 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Spc7_N PF15402.1 CDI80050.1 - 1.7 6.5 27.3 2.4 6.0 18.9 1.2 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 DUF2217 PF10265.4 CDI80050.1 - 1.9 7.1 15.7 2.5 6.7 10.9 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) SAGA-Tad1 PF12767.2 CDI80050.1 - 2.3 7.8 28.8 2.7 7.5 20.0 1.1 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit SOBP PF15279.1 CDI80050.1 - 3.7 7.8 28.9 4 7.7 20.0 1.0 1 0 0 1 1 1 0 Sine oculis-binding protein DUF2215 PF10225.4 CDI80050.1 - 4.7 6.5 14.8 5.8 6.2 10.3 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) K_trans PF02705.11 CDI80050.1 - 8.3 4.6 7.4 9.6 4.4 5.1 1.1 1 0 0 1 1 1 0 K+ potassium transporter Potyvirid-P3 PF13608.1 CDI80068.1 - 0.013 14.6 0.6 0.013 14.6 0.4 2.9 2 1 0 3 3 3 0 Protein P3 of Potyviral polyprotein DUF1754 PF08555.5 CDI80093.1 - 6.4e-05 23.4 0.1 6.4e-05 23.4 0.1 2.6 2 1 0 2 2 2 1 Eukaryotic family of unknown function (DUF1754) zf-C3HC4_4 PF15227.1 CDI80095.1 - 1.1e-05 25.1 7.1 1.1e-05 25.1 4.9 4.1 4 0 0 4 4 4 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.1 CDI80095.1 - 8.3e-05 22.5 7.4 8.3e-05 22.5 5.1 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) IncA PF04156.9 CDI80096.1 - 5.5e-08 32.6 16.9 5.5e-08 32.6 11.7 2.4 2 1 0 2 2 2 1 IncA protein Med15 PF09606.5 CDI80096.1 - 0.00026 19.3 84.8 0.00031 19.1 58.8 1.1 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal PAT1 PF09770.4 CDI80096.1 - 0.64 8.1 70.4 0.74 7.9 48.8 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 PP2C PF00481.16 CDI80097.1 - 1.6e-12 47.3 5.6 3.6e-10 39.6 2.6 4.7 4 1 0 4 4 4 2 Protein phosphatase 2C FimP PF09766.4 CDI80111.1 - 0.059 12.4 9.3 0.076 12.0 6.4 1.1 1 0 0 1 1 1 0 Fms-interacting protein G0-G1_switch_2 PF15103.1 CDI80111.1 - 0.76 10.0 5.8 1.4 9.1 4.1 1.4 1 0 0 1 1 1 0 G0/G1 switch protein 2 Hid1 PF12722.2 CDI80111.1 - 1.4 6.4 5.0 1.3 6.5 3.4 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF4557 PF15101.1 CDI80111.1 - 1.7 8.4 10.7 2.7 7.8 7.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) SOBP PF15279.1 CDI80111.1 - 2.3 8.5 13.9 3.1 8.1 9.6 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein Plasmodium_Vir PF05795.6 CDI80111.1 - 2.3 7.3 4.1 3.4 6.7 2.9 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein SR-25 PF10500.4 CDI80111.1 - 2.5 7.5 33.2 0.0089 15.5 11.5 2.0 1 1 1 2 2 2 0 Nuclear RNA-splicing-associated protein DUF4544 PF15077.1 CDI80111.1 - 3.8 6.9 7.1 5.4 6.4 4.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4544) DUF1980 PF09323.5 CDI80111.1 - 5 6.8 6.3 7.9 6.1 4.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) DUF4629 PF15442.1 CDI80112.1 - 0.67 10.0 12.4 0.86 9.7 8.4 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4629) Pox_Ag35 PF03286.9 CDI80112.1 - 2 7.8 12.8 1.9 7.9 8.6 1.3 1 1 0 1 1 1 0 Pox virus Ag35 surface protein GAGA_bind PF06217.7 CDI80112.1 - 3.1 7.6 12.9 3.7 7.4 8.9 1.0 1 0 0 1 1 1 0 GAGA binding protein-like family Calc_CGRP_IAPP PF00214.14 CDI80112.1 - 3.6 7.6 10.6 6.6 6.7 7.3 1.6 1 1 0 1 1 1 0 Calcitonin / CGRP / IAPP family PAT1 PF09770.4 CDI80112.1 - 6.4 4.8 20.1 7.1 4.7 13.9 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Med15 PF09606.5 CDI80113.1 - 0.011 14.0 23.5 0.012 13.9 16.3 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF1469 PF07332.6 CDI80113.1 - 0.43 10.3 8.9 0.67 9.6 6.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1469) Pex24p PF06398.6 CDI80125.1 - 0.0011 17.8 0.3 0.0011 17.8 0.2 3.6 3 1 0 3 3 3 1 Integral peroxisomal membrane peroxin DUF755 PF05501.6 CDI80125.1 - 0.004 17.2 7.4 0.004 17.2 5.1 7.3 6 1 1 7 7 7 1 Domain of unknown function (DUF755) DUF1628 PF07790.6 CDI80125.1 - 0.024 15.3 0.1 0.024 15.3 0.0 4.0 6 0 0 6 6 6 0 Protein of unknown function (DUF1628) DUF1510 PF07423.6 CDI80125.1 - 0.061 12.6 0.1 0.061 12.6 0.1 5.9 5 1 1 6 6 6 0 Protein of unknown function (DUF1510) Tetraspannin PF00335.15 CDI80125.1 - 0.061 12.5 0.3 0.061 12.5 0.2 4.6 4 1 0 4 4 4 0 Tetraspanin family OAD_gamma PF04277.8 CDI80125.1 - 0.25 11.7 0.1 0.25 11.7 0.1 6.4 7 1 1 8 8 8 0 Oxaloacetate decarboxylase, gamma chain DUF4097 PF13349.1 CDI80125.1 - 0.49 9.9 2.0 5.4 6.5 0.0 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4097) THRAP3_BCLAF1 PF15440.1 CDI80129.1 - 0.0013 17.5 36.9 0.0015 17.3 25.6 1.0 1 0 0 1 1 1 1 THRAP3/BCLAF1 family CAF-1_p150 PF11600.3 CDI80129.1 - 0.0091 15.4 41.8 0.011 15.0 29.0 1.1 1 0 0 1 1 1 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal SDA1 PF05285.7 CDI80129.1 - 0.013 14.8 22.3 0.015 14.5 15.5 1.0 1 0 0 1 1 1 0 SDA1 Nop53 PF07767.6 CDI80129.1 - 0.051 12.5 29.5 0.06 12.3 20.4 1.0 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) CKAP2_C PF15297.1 CDI80129.1 - 0.052 12.3 25.3 0.068 11.9 17.5 1.2 1 0 0 1 1 1 0 Cytoskeleton-associated protein 2 C-terminus DUF4175 PF13779.1 CDI80129.1 - 0.079 10.6 50.6 0.076 10.7 35.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Borrelia_P83 PF05262.6 CDI80129.1 - 0.2 9.9 21.5 0.22 9.7 14.9 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein SprA-related PF12118.3 CDI80129.1 - 0.25 10.6 61.1 0.32 10.2 42.3 1.1 1 0 0 1 1 1 0 SprA-related family LicD PF04991.8 CDI80129.1 - 0.26 11.3 4.9 0.36 10.9 3.4 1.3 1 0 0 1 1 1 0 LicD family SAGA-Tad1 PF12767.2 CDI80129.1 - 0.46 10.1 37.0 0.55 9.8 25.6 1.0 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit Peptidase_S15 PF02129.13 CDI80129.1 - 0.6 9.4 14.4 0.69 9.2 10.0 1.1 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Tim54 PF11711.3 CDI80129.1 - 0.69 8.4 15.2 0.9 8.0 10.5 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 TFIIA PF03153.8 CDI80129.1 - 0.8 9.5 45.4 0.92 9.3 31.4 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Hex_IIIa PF02455.11 CDI80129.1 - 0.8 8.3 21.2 0.95 8.0 14.7 1.0 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) FixO PF02433.10 CDI80129.1 - 1.1 8.5 8.9 1.3 8.3 6.2 1.3 1 0 0 1 1 1 0 Cytochrome C oxidase, mono-heme subunit/FixO Med15 PF09606.5 CDI80129.1 - 1.2 7.2 64.5 1.3 7.1 44.7 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal PAT1 PF09770.4 CDI80129.1 - 1.3 7.1 52.3 1.4 7.0 36.3 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 NARP1 PF12569.3 CDI80129.1 - 1.3 7.6 23.3 1.5 7.4 16.2 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 GAGA_bind PF06217.7 CDI80129.1 - 1.4 8.8 26.1 1.4 8.7 18.1 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family DUF4045 PF13254.1 CDI80129.1 - 1.7 7.8 31.1 2.2 7.5 21.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) DUF763 PF05559.6 CDI80129.1 - 1.8 7.4 11.5 1.9 7.3 7.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF763) Utp14 PF04615.8 CDI80129.1 - 1.9 6.5 36.4 2.2 6.3 25.2 1.0 1 0 0 1 1 1 0 Utp14 protein RR_TM4-6 PF06459.7 CDI80129.1 - 2 8.2 29.0 2.5 7.8 20.1 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF4407 PF14362.1 CDI80129.1 - 2.2 7.1 26.5 2.6 6.9 18.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF501 PF04417.7 CDI80129.1 - 2.9 7.7 8.7 3.8 7.3 6.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF501) DUF4603 PF15376.1 CDI80129.1 - 3.4 4.7 25.9 3.7 4.5 18.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) eIF-3_zeta PF05091.7 CDI80129.1 - 3.9 5.9 32.2 4.5 5.7 22.3 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF3337 PF11816.3 CDI80129.1 - 4 6.7 25.9 4.8 6.4 18.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3337) DUF4355 PF14265.1 CDI80129.1 - 4.3 7.3 31.0 5.5 6.9 21.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4355) eIF3_subunit PF08597.5 CDI80129.1 - 4.4 6.7 23.2 5.8 6.4 16.1 1.3 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit SOBP PF15279.1 CDI80129.1 - 4.4 7.5 33.4 4.9 7.4 23.2 1.0 1 0 0 1 1 1 0 Sine oculis-binding protein DUF853 PF05872.7 CDI80129.1 - 4.6 5.4 19.5 5.1 5.3 13.5 1.0 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) AUX_IAA PF02309.11 CDI80129.1 - 5.7 6.6 26.2 9.2 5.9 18.2 1.3 1 0 0 1 1 1 0 AUX/IAA family GNT-I PF03071.10 CDI80129.1 - 6.1 5.2 14.3 7.4 5.0 9.9 1.2 1 0 0 1 1 1 0 GNT-I family Ycf1 PF05758.7 CDI80129.1 - 6.3 4.3 25.8 7 4.2 17.9 1.0 1 0 0 1 1 1 0 Ycf1 Cellulose_synt PF03552.9 CDI80129.1 - 6.4 4.9 12.6 7 4.8 8.8 1.1 1 0 0 1 1 1 0 Cellulose synthase Parvo_coat PF00740.13 CDI80129.1 - 6.5 5.5 28.0 7.5 5.3 19.4 1.0 1 0 0 1 1 1 0 Parvovirus coat protein VP2 DUF4011 PF13195.1 CDI80129.1 - 6.8 6.6 15.7 8.6 6.3 10.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4011) DUF1510 PF07423.6 CDI80129.1 - 6.9 5.9 33.1 11 5.2 22.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DDRGK PF09756.4 CDI80129.1 - 7 6.0 29.8 9.8 5.5 20.6 1.3 1 0 0 1 1 1 0 DDRGK domain Dsh_C PF12316.3 CDI80129.1 - 7.3 6.6 29.9 10 6.1 20.8 1.3 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal Asp-B-Hydro_N PF05279.6 CDI80129.1 - 8.8 6.1 19.2 11 5.8 13.3 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region DUF2126 PF09899.4 CDI80129.1 - 9.8 4.0 15.4 10 3.9 10.7 1.1 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) Kelch_3 PF13415.1 CDI80145.1 - 1.2e-10 41.2 4.3 1.7e-06 28.0 0.3 4.3 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_1 PF01344.20 CDI80145.1 - 1.9e-09 36.9 0.0 4.3e-06 26.1 0.0 2.7 2 0 0 2 2 2 2 Kelch motif Kelch_4 PF13418.1 CDI80145.1 - 2.7e-09 36.6 4.0 0.00021 20.9 0.0 4.5 4 0 0 4 4 4 3 Galactose oxidase, central domain Kelch_6 PF13964.1 CDI80145.1 - 3.9e-08 33.1 2.1 0.0083 16.2 0.0 4.8 4 0 0 4 4 4 2 Kelch motif Kelch_2 PF07646.10 CDI80145.1 - 1.4e-07 31.0 2.7 0.0028 17.3 1.3 3.7 3 1 0 3 3 3 2 Kelch motif Kelch_5 PF13854.1 CDI80145.1 - 2.8e-06 27.1 0.1 0.00024 20.9 0.1 3.3 3 0 0 3 3 3 1 Kelch motif Spore_coat_CotO PF14153.1 CDI80145.1 - 0.00056 19.4 8.8 0.00056 19.4 6.1 4.1 3 1 0 3 3 3 1 Spore coat protein CotO Paf1 PF03985.8 CDI80178.1 - 0.068 11.9 15.9 0.089 11.5 11.0 1.1 1 0 0 1 1 1 0 Paf1 UPF0560 PF10577.4 CDI80178.1 - 0.79 7.9 16.6 0.86 7.7 11.5 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Gti1_Pac2 PF09729.4 CDI80178.1 - 1 9.2 8.4 1.9 8.3 5.8 1.5 1 0 0 1 1 1 0 Gti1/Pac2 family Herpes_DNAp_acc PF04929.7 CDI80178.1 - 1.4 7.7 13.9 1.7 7.5 7.5 1.9 1 1 0 1 1 1 0 Herpes DNA replication accessory factor SUFU_C PF12470.3 CDI80178.1 - 1.6 8.2 8.7 3.4 7.2 6.0 1.5 1 0 0 1 1 1 0 Suppressor of Fused Gli/Ci N terminal binding domain Ycf1 PF05758.7 CDI80178.1 - 1.9 6.1 15.5 2.5 5.7 10.7 1.1 1 0 0 1 1 1 0 Ycf1 AAA_23 PF13476.1 CDI80178.1 - 1.9 8.7 20.5 2.4 8.4 14.2 1.1 1 0 0 1 1 1 0 AAA domain Hid1 PF12722.2 CDI80178.1 - 3 5.4 16.3 4 5.0 11.3 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SID-1_RNA_chan PF13965.1 CDI80178.1 - 4.5 5.3 9.7 5.6 4.9 6.7 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 AMMECR1 PF01871.12 CDI80209.1 - 5.8e-07 28.8 0.0 5.8e-07 28.8 0.0 2.5 3 0 0 3 3 3 1 AMMECR1 TMEM151 PF14857.1 CDI80209.1 - 0.0032 16.1 7.5 0.0042 15.7 5.2 1.1 1 0 0 1 1 1 1 TMEM151 family NMDAR2_C PF10565.4 CDI80209.1 - 0.014 14.1 20.4 0.019 13.6 14.2 1.2 1 0 0 1 1 1 0 N-methyl D-aspartate receptor 2B3 C-terminus Sporozoite_P67 PF05642.6 CDI80209.1 - 0.36 8.6 4.5 0.6 7.8 3.1 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen RAP1 PF07218.6 CDI80209.1 - 1.6 6.7 5.4 2 6.4 3.7 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) FUSC PF04632.7 CDI80209.1 - 9.1 4.5 14.3 11 4.3 9.9 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Tim54 PF11711.3 CDI80212.1 - 3.5 6.1 15.5 5.8 5.3 10.7 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 BTV_NS2 PF04514.7 CDI80212.1 - 3.6 6.3 24.7 4.5 6.0 17.1 1.0 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 GAGA_bind PF06217.7 CDI80212.1 - 4.1 7.2 27.7 4.9 7.0 19.2 1.0 1 0 0 1 1 1 0 GAGA binding protein-like family U1snRNP70_N PF12220.3 CDI80222.1 - 0.027 14.8 2.1 0.027 14.8 1.4 8.6 5 2 2 8 8 8 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal Pkinase PF00069.20 CDI80231.1 - 8.8e-58 195.4 0.0 1.1e-57 195.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDI80231.1 - 8.5e-32 110.2 0.0 1.1e-31 109.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CDI80231.1 - 1.9e-08 33.6 0.0 2.4e-08 33.3 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 CDI80231.1 - 3.2e-05 23.0 0.1 4e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 CDI80231.1 - 0.0005 19.4 0.2 0.00066 19.0 0.1 1.1 1 0 0 1 1 1 1 RIO1 family APH PF01636.18 CDI80231.1 - 0.00054 19.7 0.8 0.018 14.8 0.3 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family YukC PF10140.4 CDI80231.1 - 0.004 15.7 0.1 0.0045 15.5 0.0 1.1 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukC Choline_kinase PF01633.15 CDI80231.1 - 0.019 14.5 0.3 0.023 14.2 0.2 1.3 1 1 0 1 1 1 0 Choline/ethanolamine kinase YrbL-PhoP_reg PF10707.4 CDI80231.1 - 0.14 11.4 0.0 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Glucan_synthase PF02364.10 CDI80237.1 - 3.2e-123 412.3 12.6 2.1e-106 356.7 9.0 3.0 2 2 0 2 2 2 2 1,3-beta-glucan synthase component FtsJ PF01728.14 CDI80239.1 - 0.016 15.1 0.1 0.037 14.0 0.0 1.6 1 0 0 1 1 1 0 FtsJ-like methyltransferase DUF4081 PF13312.1 CDI80239.1 - 0.077 12.9 0.2 2.8 7.9 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4081) AAA_23 PF13476.1 CDI80244.1 - 2.4 8.4 20.2 0.32 11.3 9.9 2.1 2 0 0 2 2 2 0 AAA domain SelP_N PF04592.9 CDI80248.1 - 3.7 6.8 31.6 4.2 6.6 21.9 1.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region DUF702 PF05142.7 CDI80248.1 - 8.4 6.5 19.5 11 6.2 13.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF702) DUF3881 PF12997.2 CDI80249.1 - 0.061 12.3 5.5 0.079 11.9 3.8 1.2 1 0 0 1 1 1 0 Domain of unknown function, E. rectale Gene description (DUF3881) DUF4483 PF14825.1 CDI80249.1 - 0.36 10.4 13.8 0.43 10.2 9.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4483) DUF1754 PF08555.5 CDI80249.1 - 0.56 10.8 11.8 0.77 10.3 8.2 1.2 1 0 0 1 1 1 0 Eukaryotic family of unknown function (DUF1754) Fumble PF03630.9 CDI80249.1 - 0.86 8.3 5.9 0.99 8.1 4.1 1.1 1 0 0 1 1 1 0 Fumble FAM60A PF15396.1 CDI80249.1 - 1.3 8.7 8.5 1.5 8.5 5.9 1.1 1 0 0 1 1 1 0 Protein Family FAM60A PAT1 PF09770.4 CDI80249.1 - 1.3 7.1 37.1 1.3 7.1 25.7 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DDHD PF02862.12 CDI80249.1 - 1.4 8.6 11.4 1.7 8.3 7.9 1.1 1 0 0 1 1 1 0 DDHD domain Ofd1_CTDD PF10637.4 CDI80249.1 - 1.7 7.6 9.1 1.9 7.5 6.3 1.1 1 0 0 1 1 1 0 Oxoglutarate and iron-dependent oxygenase degradation C-term Nitroreductase PF00881.19 CDI80249.1 - 2.9 7.6 8.7 4 7.2 6.1 1.4 1 1 0 1 1 1 0 Nitroreductase family GPCR_chapero_1 PF11904.3 CDI80249.1 - 3.3 6.7 10.0 4 6.4 6.9 1.1 1 0 0 1 1 1 0 GPCR-chaperone DUF4613 PF15390.1 CDI80249.1 - 3.5 5.6 10.6 4 5.4 7.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) Asp-B-Hydro_N PF05279.6 CDI80249.1 - 4.1 7.1 10.4 4.7 6.9 7.2 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region DUF4544 PF15077.1 CDI80249.1 - 6.7 6.1 9.4 8.5 5.7 6.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4544) 2OG-FeII_Oxy_5 PF13759.1 CDI80249.1 - 8.2 6.7 8.2 16 5.8 5.0 1.9 1 1 1 2 2 2 0 Putative 2OG-Fe(II) oxygenase TFIIA PF03153.8 CDI80249.1 - 9.4 6.0 26.6 11 5.7 18.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4175 PF13779.1 CDI80249.1 - 9.8 3.7 42.0 11 3.5 29.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) SOBP PF15279.1 CDI80256.1 - 0.00018 22.0 19.0 0.00018 22.0 13.2 3.3 2 1 0 2 2 2 1 Sine oculis-binding protein BAF1_ABF1 PF04684.8 CDI80256.1 - 0.0056 15.6 13.8 0.0056 15.6 9.6 7.1 5 1 1 7 7 7 2 BAF1 / ABF1 chromatin reorganising factor FAM176 PF14851.1 CDI80256.1 - 0.086 12.5 0.1 0.086 12.5 0.1 4.5 4 1 0 4 4 4 0 FAM176 family PAT1 PF09770.4 CDI80256.1 - 3.2 5.8 90.7 0.043 12.0 16.9 3.2 3 0 0 3 3 3 0 Topoisomerase II-associated protein PAT1 DUF572 PF04502.8 CDI80256.1 - 8.5 5.4 47.3 0.12 11.6 0.2 4.1 4 0 0 4 4 4 0 Family of unknown function (DUF572) Med15 PF09606.5 CDI80266.1 - 0.0055 14.9 45.7 0.0071 14.6 31.7 1.2 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal RLL PF10036.4 CDI80266.1 - 0.087 12.2 0.3 0.087 12.2 0.2 2.5 2 1 1 3 3 3 0 Putative carnitine deficiency-associated protein DUF3959 PF13105.1 CDI80266.1 - 0.098 11.9 4.4 0.13 11.5 3.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3959) Phage_int_SAM_5 PF13102.1 CDI80266.1 - 0.25 11.3 6.7 0.52 10.3 4.6 1.5 1 0 0 1 1 1 0 Phage integrase SAM-like domain PAT1 PF09770.4 CDI80266.1 - 0.99 7.5 40.4 1.3 7.2 28.0 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 UPF0052 PF01933.13 CDI80266.1 - 1.2 8.4 4.0 2 7.6 2.8 1.3 1 0 0 1 1 1 0 Uncharacterised protein family UPF0052 DUF2828 PF11443.3 CDI80266.1 - 1.2 7.2 10.7 0.55 8.3 5.7 1.4 1 1 1 2 2 2 0 Domain of unknown function (DUF2828) tRNA_synt_1c_R2 PF04557.10 CDI80266.1 - 1.3 9.7 10.4 0.8 10.4 2.2 2.4 2 0 0 2 2 2 0 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 DUF1631 PF07793.6 CDI80266.1 - 6.5 4.7 34.1 7.6 4.5 23.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) AAA_23 PF13476.1 CDI80266.1 - 9.2 6.5 23.2 12 6.1 16.1 1.2 1 0 0 1 1 1 0 AAA domain TMEM51 PF15345.1 CDI80269.1 - 0.0046 16.6 0.8 0.0046 16.6 0.6 5.8 6 1 0 6 6 6 1 Transmembrane protein 51 Rxt3 PF08642.5 CDI80269.1 - 0.51 10.5 0.0 0.51 10.5 0.0 4.6 4 1 1 5 5 5 0 Histone deacetylation protein Rxt3 Herpes_UL87 PF03043.9 CDI80269.1 - 9.6 4.4 20.0 2.4 6.4 1.1 3.5 2 1 0 3 3 3 0 Herpesvirus UL87 family Beta-lactamase PF00144.19 CDI80271.1 - 0.18 10.7 6.9 0.047 12.7 2.6 1.4 1 1 0 1 1 1 0 Beta-lactamase DUF1028 PF06267.7 CDI80271.1 - 3.6 6.9 13.8 5.4 6.4 3.2 2.4 1 1 1 2 2 2 0 Family of unknown function (DUF1028) Pol_alpha_B_N PF08418.5 CDI80272.1 - 0.012 15.1 4.7 0.014 14.9 3.3 1.0 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal Bindin PF02084.10 CDI80272.1 - 0.46 10.4 6.6 0.51 10.3 4.6 1.0 1 0 0 1 1 1 0 Bindin Ribosomal_60s PF00428.14 CDI80272.1 - 0.86 10.0 13.5 1.4 9.3 9.3 1.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein Med15 PF09606.5 CDI80272.1 - 2 6.4 11.0 2.7 6.0 7.6 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal RAP1 PF07218.6 CDI80272.1 - 3.6 5.5 8.5 4 5.4 5.9 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DUF3138 PF11336.3 CDI80272.1 - 3.9 5.5 11.4 3.7 5.6 7.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Auxin_canalis PF05703.6 CDI80272.1 - 4.6 6.9 16.6 6 6.6 11.5 1.4 1 1 0 1 1 1 0 Auxin canalisation Herpes_capsid PF06112.6 CDI80272.1 - 6.6 6.7 19.9 10 6.1 13.8 1.2 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein DUF2681 PF10883.3 CDI80273.1 - 0.012 15.7 5.8 0.012 15.7 4.0 2.2 2 0 0 2 2 1 0 Protein of unknown function (DUF2681) Usp PF00582.21 CDI80273.1 - 0.062 13.4 0.1 0.062 13.4 0.1 1.4 2 0 0 2 2 1 0 Universal stress protein family DUF4407 PF14362.1 CDI80273.1 - 0.19 10.6 14.3 0.24 10.3 9.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) PAS PF00989.19 CDI80273.1 - 0.24 11.2 5.8 2.1 8.1 0.1 2.1 2 0 0 2 2 2 0 PAS fold G-alpha PF00503.15 CDI80273.1 - 0.31 9.6 5.9 0.37 9.4 4.1 1.1 1 0 0 1 1 1 0 G-protein alpha subunit DUF3043 PF11241.3 CDI80273.1 - 0.69 9.4 7.8 1.6 8.2 2.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3043) PBP1_TM PF14812.1 CDI80273.1 - 0.74 10.1 3.0 1.9 8.8 0.6 2.0 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Pneumo_phosprot PF02478.11 CDI80273.1 - 0.77 9.2 5.1 0.88 9.0 3.5 1.2 1 0 0 1 1 1 0 Pneumovirus phosphoprotein Hid1 PF12722.2 CDI80273.1 - 0.8 7.3 11.1 0.96 7.0 7.7 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein FAM176 PF14851.1 CDI80273.1 - 0.98 9.0 5.6 0.14 11.8 0.7 1.8 2 0 0 2 2 2 0 FAM176 family CDK2AP PF09806.4 CDI80273.1 - 1.2 9.3 18.6 0.82 9.8 7.9 2.0 2 0 0 2 2 2 0 Cyclin-dependent kinase 2-associated protein Peptidase_S49_N PF08496.5 CDI80273.1 - 1.3 8.7 6.9 0.62 9.8 1.5 2.0 2 0 0 2 2 2 0 Peptidase family S49 N-terminal DUF1644 PF07800.7 CDI80273.1 - 1.3 8.8 6.8 8.9 6.1 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1644) Endonuc_Holl PF10107.4 CDI80273.1 - 1.4 8.5 8.0 0.15 11.7 1.2 1.9 2 0 0 2 2 2 0 Endonuclease related to archaeal Holliday junction resolvase Presenilin PF01080.12 CDI80273.1 - 1.6 7.4 7.5 2 7.1 5.2 1.1 1 0 0 1 1 1 0 Presenilin PSCyt3 PF07627.6 CDI80273.1 - 2 8.3 8.0 5.3 6.9 4.8 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1588) Folate_carrier PF01770.13 CDI80273.1 - 2 6.8 5.9 2.8 6.3 4.1 1.4 1 1 0 1 1 1 0 Reduced folate carrier DUF2126 PF09899.4 CDI80273.1 - 2.2 6.2 8.3 2.3 6.1 5.8 1.0 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) Dicty_REP PF05086.7 CDI80273.1 - 2.5 5.7 11.9 3.7 5.1 8.2 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF912 PF06024.7 CDI80273.1 - 3.1 7.8 7.6 11 6.0 2.9 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) FCP1_C PF09309.5 CDI80273.1 - 4.2 6.5 17.8 1.3 8.2 5.3 2.1 2 0 0 2 2 2 0 FCP1, C-terminal RNA_pol_Rpc4 PF05132.9 CDI80273.1 - 4.6 7.2 12.1 0.72 9.8 4.2 2.0 2 0 0 2 2 2 0 RNA polymerase III RPC4 Bud13 PF09736.4 CDI80273.1 - 5.5 7.2 15.4 3 8.0 5.2 2.0 2 0 0 2 2 2 0 Pre-mRNA-splicing factor of RES complex Mcm10 PF09332.6 CDI80273.1 - 7.1 5.8 16.8 0.024 14.0 4.4 1.8 2 0 0 2 2 2 0 Mcm10 replication factor PAT1 PF09770.4 CDI80273.1 - 7.6 4.6 34.5 8.6 4.4 23.9 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Dynamin_N PF00350.18 CDI80273.1 - 8.1 6.2 8.8 0.38 10.5 2.0 1.7 1 1 1 2 2 2 0 Dynamin family SAE2 PF08573.5 CDI80273.1 - 9.8 6.9 7.8 2.2 9.0 1.7 2.0 2 0 0 2 2 2 0 DNA repair protein endonuclease SAE2/CtIP C-terminus MIP-T3 PF10243.4 CDI80274.1 - 0.089 11.2 68.3 0.12 10.8 47.3 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Spore_coat_CotO PF14153.1 CDI80289.1 - 0.0016 17.9 29.4 0.0016 17.9 20.4 5.0 5 0 0 5 5 5 1 Spore coat protein CotO DUF1003 PF06210.6 CDI80289.1 - 0.0079 16.1 0.7 0.0079 16.1 0.5 4.9 3 1 2 5 5 5 1 Protein of unknown function (DUF1003) RskA PF10099.4 CDI80290.1 - 0.00041 20.1 1.6 0.00066 19.4 1.1 1.3 1 0 0 1 1 1 1 Anti-sigma-K factor rskA DUF4259 PF14078.1 CDI80290.1 - 0.79 10.2 3.1 1.9 9.0 2.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4259) Ribosomal_60s PF00428.14 CDI80290.1 - 2 8.8 8.8 0.2 12.0 2.8 1.7 2 0 0 2 2 2 0 60s Acidic ribosomal protein DUF3617 PF12276.3 CDI80290.1 - 5.7 6.3 18.0 15 5.0 12.5 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3617) Arteri_nucleo PF01481.11 CDI80295.1 - 0.083 12.9 0.1 0.13 12.3 0.0 1.2 1 0 0 1 1 1 0 Arterivirus nucleocapsid protein HEAT_2 PF13646.1 CDI80295.1 - 0.2 11.9 9.3 0.38 11.0 2.6 3.0 2 1 0 2 2 2 0 HEAT repeats tRNA-synt_2b PF00587.20 CDI80303.1 - 3.5e-24 85.2 0.0 5e-24 84.8 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA-synt_2 PF00152.15 CDI80303.1 - 0.21 10.3 0.0 0.32 9.7 0.0 1.2 1 0 0 1 1 1 0 tRNA synthetases class II (D, K and N) Glycos_transf_1 PF00534.15 CDI80304.1 - 3.9e-19 68.6 0.0 4.1e-09 36.0 0.0 2.1 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 CDI80304.1 - 4.1e-06 26.9 0.0 8.5e-05 22.7 0.0 2.2 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 CDI80304.1 - 0.00012 22.2 0.0 0.00021 21.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Vps51 PF08700.6 CDI80310.1 - 8.5e-05 22.3 0.0 0.00021 21.0 0.0 1.6 1 0 0 1 1 1 1 Vps51/Vps67 DUF2664 PF10867.3 CDI80310.1 - 0.0045 17.5 3.4 0.0089 16.6 0.1 2.9 3 0 0 3 3 3 1 Protein of unknown function (DUF2664) MA3 PF02847.12 CDI80313.1 - 0.0054 16.4 0.1 0.016 14.9 0.1 1.9 1 0 0 1 1 1 1 MA3 domain SNF2_N PF00176.18 CDI80324.1 - 2.3e-50 171.1 0.0 3.4e-50 170.5 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 CDI80324.1 - 1.5e-12 47.2 0.0 3e-12 46.2 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 CDI80324.1 - 1.8e-05 24.2 0.0 3.3e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 CDI80324.1 - 2.9e-05 23.9 0.0 6.7e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.3 CDI80324.1 - 0.00014 20.8 0.0 0.00042 19.2 0.0 1.7 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 DUF2075 PF09848.4 CDI80324.1 - 0.014 14.4 0.1 0.037 12.9 0.0 1.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.1 CDI80324.1 - 0.081 13.0 0.0 0.46 10.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain RNA_GG_bind PF10258.4 CDI80331.1 - 2.2e-23 81.7 0.0 3.8e-23 80.9 0.0 1.4 1 0 0 1 1 1 1 PHAX RNA-binding domain HDPD PF02924.9 CDI80331.1 - 0.093 12.5 0.0 0.2 11.4 0.0 1.5 1 0 0 1 1 1 0 Bacteriophage lambda head decoration protein D HCV_capsid PF01543.12 CDI80331.1 - 0.74 9.8 4.4 4.5 7.2 1.6 2.3 2 0 0 2 2 2 0 Hepatitis C virus capsid protein rve PF00665.21 CDI80337.1 - 1.7e-18 66.8 0.0 4.9e-18 65.3 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.5 CDI80337.1 - 0.073 12.4 0.1 0.19 11.1 0.1 1.8 1 0 0 1 1 1 0 His(2)-Cys(2) zinc finger RVP PF00077.15 CDI80340.1 - 9.6e-06 25.4 0.0 2.1e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.1 CDI80340.1 - 2.8e-05 24.5 0.0 6.4e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.6 CDI80340.1 - 3.2e-05 23.8 0.0 7.5e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 CDI80340.1 - 0.0005 19.8 0.1 0.0013 18.5 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease zf-CCHC PF00098.18 CDI80340.1 - 0.04 13.8 1.3 0.04 13.8 0.9 2.2 3 0 0 3 3 3 0 Zinc knuckle Asp_protease PF09668.5 CDI80340.1 - 0.043 13.3 0.0 0.081 12.4 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease ABC1 PF03109.11 CDI80344.1 - 6.3e-15 55.2 0.0 8.1e-11 41.9 0.0 2.3 2 0 0 2 2 2 2 ABC1 family ICAM_N PF03921.9 CDI80344.1 - 0.035 13.5 0.0 0.079 12.4 0.0 1.5 1 0 0 1 1 1 0 Intercellular adhesion molecule (ICAM), N-terminal domain Helicase_C PF00271.26 CDI80355.1 - 7.2e-08 32.1 0.1 1.7e-07 31.0 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 CDI80355.1 - 3.6e-05 23.3 0.4 0.00012 21.6 0.3 1.9 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_19 PF13245.1 CDI80355.1 - 0.0092 15.7 0.3 0.035 13.8 0.2 2.0 1 0 0 1 1 1 1 Part of AAA domain HA2 PF04408.18 CDI80355.1 - 0.041 13.9 0.1 0.041 13.9 0.0 2.1 2 0 0 2 2 2 0 Helicase associated domain (HA2) ABC_tran PF00005.22 CDI80355.1 - 0.05 13.8 0.0 0.17 12.1 0.0 1.9 1 0 0 1 1 1 0 ABC transporter T2SE PF00437.15 CDI80355.1 - 0.088 11.7 0.1 0.18 10.7 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_23 PF13476.1 CDI80355.1 - 1.5 9.0 8.5 0.33 11.2 0.4 2.4 2 0 0 2 2 2 0 AAA domain DUF4207 PF13904.1 CDI80356.1 - 0.64 9.3 28.4 0.16 11.3 5.4 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4207) Ycf1 PF05758.7 CDI80356.1 - 1.1 6.8 4.4 1.6 6.3 3.1 1.2 1 0 0 1 1 1 0 Ycf1 Atg14 PF10186.4 CDI80356.1 - 2.4 7.0 25.7 1 8.2 10.1 2.8 2 1 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 IncA PF04156.9 CDI80356.1 - 3.6 7.1 38.2 0.098 12.2 12.1 3.6 3 0 0 3 3 3 0 IncA protein PPTA PF01239.17 CDI80393.1 - 1.7e-07 30.2 3.6 0.0091 15.3 0.0 3.0 2 1 0 2 2 2 2 Protein prenyltransferase alpha subunit repeat Med15 PF09606.5 CDI80393.1 - 0.0014 16.9 22.3 0.0014 16.9 15.4 2.1 2 0 0 2 2 2 1 ARC105 or Med15 subunit of Mediator complex non-fungal Plasmodium_Vir PF05795.6 CDI80393.1 - 0.0026 17.0 10.1 0.0026 17.0 7.0 2.1 2 0 0 2 2 2 1 Plasmodium vivax Vir protein DUF572 PF04502.8 CDI80393.1 - 0.0087 15.3 53.4 0.035 13.3 11.8 2.2 2 0 0 2 2 2 2 Family of unknown function (DUF572) AAA_23 PF13476.1 CDI80393.1 - 0.011 16.0 48.0 0.023 15.0 14.3 2.2 2 0 0 2 2 2 0 AAA domain DUF755 PF05501.6 CDI80393.1 - 0.011 15.7 35.5 0.011 15.7 24.6 3.8 2 1 1 3 3 2 0 Domain of unknown function (DUF755) Borrelia_P83 PF05262.6 CDI80393.1 - 0.012 13.8 32.7 0.0055 15.0 8.0 2.1 2 0 0 2 2 2 0 Borrelia P83/100 protein BUD22 PF09073.5 CDI80393.1 - 0.02 13.9 43.8 0.25 10.3 13.7 2.4 2 0 0 2 2 2 0 BUD22 CDC45 PF02724.9 CDI80393.1 - 0.026 12.5 42.7 0.0094 14.0 14.0 2.1 2 0 0 2 2 2 0 CDC45-like protein DNA_pol_viral_N PF00242.12 CDI80393.1 - 0.24 10.4 55.8 0.0063 15.5 15.0 2.1 2 0 0 2 2 2 0 DNA polymerase (viral) N-terminal domain Pol_alpha_B_N PF08418.5 CDI80393.1 - 0.3 10.6 44.6 0.0098 15.4 12.5 2.4 2 0 0 2 2 2 0 DNA polymerase alpha subunit B N-terminal APG6 PF04111.7 CDI80393.1 - 0.3 10.0 46.4 0.21 10.6 11.1 2.2 2 0 0 2 2 2 0 Autophagy protein Apg6 DUF1266 PF06889.6 CDI80393.1 - 0.31 10.8 21.0 1.8 8.3 2.9 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1266) Cwf_Cwc_15 PF04889.7 CDI80393.1 - 0.42 10.2 54.2 0.15 11.7 9.5 2.3 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein DUF2052 PF09747.4 CDI80393.1 - 0.56 10.1 53.7 0.78 9.6 11.3 2.4 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) RR_TM4-6 PF06459.7 CDI80393.1 - 0.69 9.7 35.1 0.56 10.0 12.1 2.3 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 DDRGK PF09756.4 CDI80393.1 - 1.3 8.3 51.1 2.5 7.4 7.8 2.4 2 0 0 2 2 2 0 DDRGK domain DUF1510 PF07423.6 CDI80393.1 - 3 7.1 58.7 0.098 12.0 19.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) DUF3381 PF11861.3 CDI80393.1 - 3.1 7.2 40.6 1.6 8.1 6.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3381) Asp-B-Hydro_N PF05279.6 CDI80393.1 - 3.8 7.2 34.3 0.28 11.0 3.5 2.1 2 0 0 2 2 2 0 Aspartyl beta-hydroxylase N-terminal region Draxin PF15550.1 CDI80393.1 - 5 6.6 38.1 0.35 10.4 9.8 2.1 2 0 0 2 2 2 0 Draxin CobT PF06213.7 CDI80393.1 - 5.3 6.0 42.9 1.5 7.8 6.2 2.2 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT DUF4045 PF13254.1 CDI80393.1 - 6 6.0 51.8 4.7 6.3 15.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4045) PAT1 PF09770.4 CDI80393.1 - 6.1 4.9 73.8 0.031 12.5 14.6 2.1 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 TRAP_alpha PF03896.11 CDI80393.1 - 7.6 5.4 23.6 1.4 7.8 6.4 2.1 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit MCR_alpha PF02249.12 CDI80407.1 - 0.54 10.2 5.2 0.62 10.0 3.6 1.1 1 0 0 1 1 1 0 Methyl-coenzyme M reductase alpha subunit, C-terminal domain DUF4392 PF14336.1 CDI80407.1 - 4.6 5.9 6.8 5 5.8 4.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4392) Thioredoxin PF00085.15 CDI80419.1 - 1e-29 102.2 0.0 1.6e-29 101.6 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 CDI80419.1 - 3.1e-09 37.0 0.0 1.9e-08 34.4 0.0 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 CDI80419.1 - 2.7e-05 24.1 0.0 0.00014 21.8 0.0 1.9 1 1 1 2 2 2 1 Thioredoxin-like Thioredoxin_7 PF13899.1 CDI80419.1 - 8.9e-05 22.4 0.0 0.00019 21.3 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_6 PF13848.1 CDI80419.1 - 0.0019 18.0 0.0 0.0029 17.4 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_3 PF13192.1 CDI80419.1 - 0.0039 16.9 0.0 0.0064 16.2 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin domain Thioredoxin_9 PF14595.1 CDI80419.1 - 0.0076 15.8 0.0 0.011 15.2 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin HyaE PF07449.6 CDI80419.1 - 0.015 15.2 0.0 0.032 14.1 0.0 1.5 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE Redoxin PF08534.5 CDI80419.1 - 0.048 13.1 0.0 0.083 12.4 0.0 1.5 1 0 0 1 1 1 0 Redoxin TraF PF13728.1 CDI80419.1 - 0.059 12.8 0.0 0.1 12.0 0.0 1.3 1 0 0 1 1 1 0 F plasmid transfer operon protein Thioredoxin_4 PF13462.1 CDI80419.1 - 0.095 12.7 0.0 1.4 8.9 0.0 2.0 1 1 1 2 2 2 0 Thioredoxin JAB PF01398.16 CDI80420.1 - 4.4e-11 42.5 0.0 8e-11 41.6 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 CDI80420.1 - 4e-10 39.7 0.0 5.7e-10 39.3 0.0 1.2 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function HTH_3 PF01381.17 CDI80420.1 - 0.033 14.0 0.0 0.061 13.1 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix Apolipoprotein PF01442.13 CDI80420.1 - 0.042 13.3 0.2 0.063 12.7 0.1 1.2 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain ALIX_LYPXL_bnd PF13949.1 CDI80421.1 - 0.086 11.7 5.6 0.32 9.9 0.6 2.7 3 0 0 3 3 3 0 ALIX V-shaped domain binding to HIV TAFH PF07531.9 CDI80421.1 - 0.63 9.7 2.7 1.9 8.2 0.1 2.6 2 1 1 3 3 3 0 NHR1 homology to TAF ATG16 PF08614.6 CDI80423.1 - 3.9e-05 23.5 8.7 3.9e-05 23.5 6.0 1.9 1 1 1 2 2 2 1 Autophagy protein 16 (ATG16) Cor1 PF04803.7 CDI80423.1 - 4.5e-05 23.2 2.4 8.3e-05 22.3 1.7 1.4 1 0 0 1 1 1 1 Cor1/Xlr/Xmr conserved region AAA_13 PF13166.1 CDI80423.1 - 0.00023 19.8 5.6 0.0003 19.4 3.9 1.2 1 0 0 1 1 1 1 AAA domain IncA PF04156.9 CDI80423.1 - 0.00039 20.0 20.0 0.00045 19.8 13.0 1.7 1 1 1 2 2 2 1 IncA protein Atg14 PF10186.4 CDI80423.1 - 0.0014 17.6 12.7 0.002 17.1 8.8 1.2 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 APG6 PF04111.7 CDI80423.1 - 0.0019 17.2 12.9 0.0024 16.9 8.9 1.1 1 0 0 1 1 1 1 Autophagy protein Apg6 Phage_lysis PF03245.8 CDI80423.1 - 0.0026 17.7 8.0 0.0026 17.7 5.5 2.5 1 1 1 2 2 2 1 Bacteriophage Rz lysis protein WEMBL PF05701.6 CDI80423.1 - 0.0029 16.1 15.6 0.0036 15.8 10.8 1.1 1 0 0 1 1 1 1 Weak chloroplast movement under blue light Spc7 PF08317.6 CDI80423.1 - 0.0033 16.1 13.7 0.0043 15.7 9.5 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein BAR_2 PF10455.4 CDI80423.1 - 0.0053 15.7 6.1 0.0067 15.3 4.2 1.1 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking TMF_TATA_bd PF12325.3 CDI80423.1 - 0.0059 16.3 11.6 0.0059 16.3 8.0 2.2 1 1 1 2 2 2 1 TATA element modulatory factor 1 TATA binding Flagellin_N PF00669.15 CDI80423.1 - 0.02 14.6 2.8 0.02 14.6 1.9 1.8 1 1 1 2 2 2 0 Bacterial flagellin N-terminal helical region Hamartin PF04388.7 CDI80423.1 - 0.035 12.8 7.6 0.073 11.7 5.3 1.6 1 1 0 1 1 1 0 Hamartin protein DivIC PF04977.10 CDI80423.1 - 0.036 13.5 18.6 0.15 11.5 4.6 3.5 3 1 1 4 4 4 0 Septum formation initiator PA28_beta PF02252.13 CDI80423.1 - 0.06 12.8 2.0 0.21 11.0 0.5 2.0 1 1 1 2 2 2 0 Proteasome activator pa28 beta subunit SlyX PF04102.7 CDI80423.1 - 0.089 13.1 18.9 0.072 13.4 2.6 3.9 1 1 3 4 4 4 0 SlyX TMF_DNA_bd PF12329.3 CDI80423.1 - 0.14 11.9 19.2 0.029 14.1 6.5 2.8 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding Med2 PF11214.3 CDI80423.1 - 0.2 11.6 7.5 0.35 10.9 5.2 1.4 1 0 0 1 1 1 0 Mediator complex subunit 2 Reo_sigmaC PF04582.7 CDI80423.1 - 0.3 10.2 2.1 2 7.5 0.8 1.7 1 1 1 2 2 2 0 Reovirus sigma C capsid protein LMP PF04778.7 CDI80423.1 - 0.33 10.6 7.1 0.53 10.0 4.9 1.4 1 1 0 1 1 1 0 LMP repeated region Glutaredoxin2_C PF04399.8 CDI80423.1 - 0.35 10.4 3.7 0.32 10.5 0.7 2.1 1 1 1 2 2 2 0 Glutaredoxin 2, C terminal domain FlaC_arch PF05377.6 CDI80423.1 - 0.37 10.7 6.8 1.1 9.2 0.1 3.0 2 1 2 4 4 4 0 Flagella accessory protein C (FlaC) Exonuc_VII_L PF02601.10 CDI80423.1 - 0.37 9.9 7.0 0.49 9.5 4.8 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit WXG100 PF06013.7 CDI80423.1 - 0.4 10.7 9.6 1.9 8.5 0.6 2.7 1 1 1 2 2 2 0 Proteins of 100 residues with WXG DivIVA PF05103.8 CDI80423.1 - 0.45 10.5 15.7 0.15 12.1 6.8 2.2 1 1 1 2 2 2 0 DivIVA protein COG2 PF06148.6 CDI80423.1 - 0.65 9.8 10.6 0.29 10.9 2.9 2.3 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF972 PF06156.8 CDI80423.1 - 0.79 10.0 11.8 0.22 11.9 3.6 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF972) SIMPL PF04402.9 CDI80423.1 - 0.85 9.4 7.8 1.9 8.3 5.4 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF541) DUF724 PF05266.9 CDI80423.1 - 0.97 9.0 13.3 2.2 7.8 9.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF724) HTH_38 PF13936.1 CDI80423.1 - 1 8.9 4.1 1.6 8.3 0.2 2.6 2 0 0 2 2 2 0 Helix-turn-helix domain DUF1732 PF08340.6 CDI80423.1 - 1.5 8.6 8.3 0.54 10.1 1.9 2.7 1 1 1 3 3 3 0 Domain of unknown function (DUF1732) FliJ PF02050.11 CDI80423.1 - 1.6 8.7 18.8 3.1 7.8 11.5 2.0 1 1 1 2 2 2 0 Flagellar FliJ protein AAA_23 PF13476.1 CDI80423.1 - 1.8 8.8 6.9 2.6 8.2 4.8 1.2 1 0 0 1 1 1 0 AAA domain SpaB_C PF14028.1 CDI80423.1 - 2.5 7.5 8.4 3.2 7.2 5.3 1.5 1 1 0 1 1 1 0 SpaB C-terminal domain HAUS-augmin3 PF14932.1 CDI80423.1 - 3.3 6.8 18.4 5 6.2 1.8 2.1 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 HALZ PF02183.13 CDI80423.1 - 3.3 7.4 14.8 3.1 7.6 0.6 4.1 4 0 0 4 4 4 0 Homeobox associated leucine zipper GvpK PF05121.7 CDI80423.1 - 3.5 7.5 11.4 0.38 10.5 2.5 2.7 1 1 2 3 3 3 0 Gas vesicle protein K V_ATPase_I PF01496.14 CDI80423.1 - 4.1 5.1 7.4 5.3 4.7 5.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family NPV_P10 PF05531.7 CDI80423.1 - 4.4 7.6 7.1 1.6e+02 2.6 3.4 3.0 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein DASH_Duo1 PF08651.5 CDI80423.1 - 4.6 6.8 8.9 24 4.5 1.7 3.5 3 1 1 4 4 3 0 DASH complex subunit Duo1 DUF1003 PF06210.6 CDI80423.1 - 4.9 7.1 10.4 1.3 8.9 2.0 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1003) BLOC1_2 PF10046.4 CDI80423.1 - 5 7.3 9.6 3.9 7.6 2.0 2.5 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF1664 PF07889.7 CDI80423.1 - 5.2 6.8 7.9 8 6.2 1.8 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) ADIP PF11559.3 CDI80423.1 - 6.5 6.6 18.1 5.2 6.9 4.8 2.1 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF2203 PF09969.4 CDI80423.1 - 7.2 6.8 12.0 4.8 7.4 1.7 2.2 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) Zein-binding PF04576.10 CDI80423.1 - 7.3 6.8 19.5 0.4 10.8 6.0 2.5 1 1 1 2 2 2 0 Zein-binding Toxin_39 PF15500.1 CDI80423.1 - 9.3 6.4 8.8 3.7 7.7 2.4 2.6 1 1 1 3 3 3 0 Putative RNase-like toxin XRCC4 PF06632.7 CDI80452.1 - 0.49 9.2 5.0 0.82 8.4 3.4 1.3 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 Adeno_PIX PF03955.9 CDI80465.1 - 0.95 10.0 18.8 1.6 9.3 2.1 2.3 2 0 0 2 2 2 0 Adenovirus hexon-associated protein (IX) DUF1777 PF08648.7 CDI80465.1 - 3.8 7.2 25.7 1.4 8.5 16.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1777) Asp-B-Hydro_N PF05279.6 CDI80465.1 - 9.7 5.9 20.0 12 5.6 13.9 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Med15 PF09606.5 CDI80470.1 - 0.00081 17.7 54.6 0.00094 17.5 37.8 1.0 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal CAF-1_p150 PF11600.3 CDI80470.1 - 0.0051 16.2 27.2 0.0072 15.7 18.8 1.1 1 0 0 1 1 1 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal SOBP PF15279.1 CDI80470.1 - 0.082 13.2 16.8 0.093 13.1 11.6 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein SR-25 PF10500.4 CDI80470.1 - 0.29 10.5 39.8 0.028 13.8 12.7 2.1 1 1 1 2 2 2 0 Nuclear RNA-splicing-associated protein AAA_11 PF13086.1 CDI80470.1 - 0.38 10.3 15.3 0.5 9.9 10.6 1.3 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.1 CDI80470.1 - 0.44 10.8 24.0 0.55 10.5 16.6 1.1 1 0 0 1 1 1 0 AAA domain PAT1 PF09770.4 CDI80470.1 - 0.64 8.1 41.4 0.78 7.9 28.7 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 GAGA_bind PF06217.7 CDI80470.1 - 1.1 9.1 17.5 1.3 8.9 12.1 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family Tyr-DNA_phospho PF06087.7 CDI80470.1 - 3.9 5.9 17.2 4.7 5.7 11.9 1.0 1 0 0 1 1 1 0 Tyrosyl-DNA phosphodiesterase Ycf1 PF05758.7 CDI80475.1 - 0.049 11.3 10.4 0.048 11.3 7.2 1.1 1 0 0 1 1 1 0 Ycf1 Pox_Ag35 PF03286.9 CDI80475.1 - 0.23 10.9 19.0 0.47 9.9 13.2 1.5 1 0 0 1 1 1 0 Pox virus Ag35 surface protein PLRV_ORF5 PF01690.12 CDI80475.1 - 1.4 8.0 26.0 2 7.4 18.0 1.2 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein FimP PF09766.4 CDI80475.1 - 5.7 5.9 24.7 8.3 5.3 17.1 1.3 1 0 0 1 1 1 0 Fms-interacting protein LMBR1 PF04791.11 CDI80475.1 - 6.9 5.1 5.7 7 5.1 4.0 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Beach PF02138.13 CDI80481.1 - 6.2e-26 91.4 0.0 1.3e-23 83.8 0.0 3.1 2 1 0 2 2 2 2 Beige/BEACH domain Pkinase PF00069.20 CDI80494.1 - 4.8e-70 235.6 0.0 6.9e-70 235.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDI80494.1 - 4.1e-36 124.3 0.0 6.1e-36 123.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CDI80494.1 - 1.3e-05 25.0 8.0 6.3e-05 22.8 0.0 3.4 3 0 0 3 3 3 2 Phosphotransferase enzyme family Kinase-like PF14531.1 CDI80494.1 - 0.00022 20.2 0.0 0.0013 17.7 0.0 2.0 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.9 CDI80494.1 - 0.0019 17.2 0.2 0.0039 16.2 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 CDI80494.1 - 0.02 14.4 0.0 0.035 13.6 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Phosducin PF02114.11 CDI80494.1 - 0.2 10.3 0.0 0.43 9.2 0.0 1.4 1 0 0 1 1 1 0 Phosducin YukC PF10140.4 CDI80494.1 - 0.61 8.5 0.0 0.94 7.9 0.0 1.2 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC YchF-GTPase_C PF06071.8 CDI80495.1 - 4e-05 23.3 2.4 0.00013 21.6 0.0 2.7 2 1 1 3 3 3 1 Protein of unknown function (DUF933) MOR2-PAG1_C PF14225.1 CDI80495.1 - 0.0056 16.4 0.5 0.0082 15.9 0.3 1.2 1 0 0 1 1 1 1 Cell morphogenesis C-terminal PEP-utilisers_N PF05524.8 CDI80495.1 - 0.056 13.2 1.1 0.1 12.3 0.8 1.4 1 0 0 1 1 1 0 PEP-utilising enzyme, N-terminal DUF1338 PF07063.8 CDI80495.1 - 0.08 11.9 2.2 0.12 11.4 1.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1338) DUF972 PF06156.8 CDI80495.1 - 0.18 12.1 4.9 1.9 8.8 0.0 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF972) Telomere_Sde2 PF13019.1 CDI80495.1 - 1.7 8.2 4.9 4.4 6.9 3.3 1.7 2 0 0 2 2 2 0 Telomere stability and silencing Rabaptin PF03528.10 CDI80496.1 - 0.0032 17.3 2.7 0.0032 17.3 1.9 2.5 3 0 0 3 3 3 1 Rabaptin Ribosomal_60s PF00428.14 CDI80496.1 - 0.027 14.8 9.9 0.027 14.8 6.9 5.6 5 1 0 5 5 5 0 60s Acidic ribosomal protein ORC4_C PF14629.1 CDI80496.1 - 0.042 13.2 0.1 0.13 11.5 0.0 2.0 1 1 0 1 1 1 0 Origin recognition complex (ORC) subunit 4 C-terminus Activator_LAG-3 PF11498.3 CDI80496.1 - 3.4 6.3 17.5 1.4 7.5 6.7 2.2 2 0 0 2 2 2 0 Transcriptional activator LAG-3 NESP55 PF06390.7 CDI80503.1 - 5e-05 22.8 30.3 5e-05 22.8 21.0 4.1 1 1 4 5 5 5 2 Neuroendocrine-specific golgi protein P55 (NESP55) Trypan_PARP PF05887.6 CDI80503.1 - 0.0038 17.0 24.5 0.0038 17.0 16.9 2.3 1 1 1 2 2 2 1 Procyclic acidic repetitive protein (PARP) NAD_binding_5 PF07994.7 CDI80503.1 - 1.3 8.4 0.0 1.3 8.4 0.0 2.6 1 1 1 2 2 2 0 Myo-inositol-1-phosphate synthase IlvGEDA_leader PF08046.6 CDI80503.1 - 6.9 5.9 7.0 11 5.2 4.9 1.3 1 0 0 1 1 1 0 IlvGEDA operon leader peptide RAB3GAP2_N PF14655.1 CDI80521.1 - 0.00013 21.1 2.9 0.00013 21.1 2.0 2.5 1 1 1 2 2 2 1 Rab3 GTPase-activating protein regulatory subunit N-terminus Med15 PF09606.5 CDI80521.1 - 0.00013 20.3 47.4 0.00013 20.3 32.9 2.1 2 0 0 2 2 2 1 ARC105 or Med15 subunit of Mediator complex non-fungal PAT1 PF09770.4 CDI80521.1 - 0.00029 19.2 35.0 0.00029 19.2 24.3 1.5 2 0 0 2 2 2 1 Topoisomerase II-associated protein PAT1 Hid1 PF12722.2 CDI80521.1 - 0.034 11.8 10.3 0.04 11.6 7.1 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein eIF-3_zeta PF05091.7 CDI80521.1 - 0.29 9.7 16.8 0.39 9.2 11.6 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) SAGA-Tad1 PF12767.2 CDI80521.1 - 0.84 9.2 21.7 1.4 8.5 15.1 1.3 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit Presenilin PF01080.12 CDI80521.1 - 2.7 6.6 11.5 7 5.3 8.0 1.7 1 0 0 1 1 1 0 Presenilin FCP1_C PF09309.5 CDI80521.1 - 5.7 6.1 24.1 1.8 7.8 6.4 2.6 2 0 0 2 2 2 0 FCP1, C-terminal DivIC PF04977.10 CDI80521.1 - 7.2 6.1 31.6 1.1 8.8 3.8 2.4 2 0 0 2 2 2 0 Septum formation initiator HlyD_2 PF12700.2 CDI80521.1 - 7.9 5.5 13.9 14 4.7 9.6 1.4 1 0 0 1 1 1 0 HlyD family secretion protein FimP PF09766.4 CDI80539.1 - 0.0022 17.1 11.1 0.0023 17.0 7.7 1.0 1 0 0 1 1 1 1 Fms-interacting protein Suf PF05843.9 CDI80539.1 - 0.004 16.9 8.3 0.004 16.9 5.7 1.0 1 0 0 1 1 1 1 Suppressor of forked protein (Suf) Spt20 PF12090.3 CDI80539.1 - 0.0041 16.4 5.8 0.0041 16.4 4.0 1.1 1 0 0 1 1 1 1 Spt20 family Cnd2 PF05786.9 CDI80539.1 - 0.006 15.1 3.7 0.0067 14.9 2.5 1.0 1 0 0 1 1 1 1 Condensin complex subunit 2 Topoisom_I_N PF02919.10 CDI80539.1 - 0.0085 15.4 1.2 0.0094 15.2 0.8 1.1 1 0 0 1 1 1 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Ctr PF04145.10 CDI80539.1 - 0.012 15.6 2.4 0.014 15.4 1.6 1.1 1 0 0 1 1 1 0 Ctr copper transporter family Glt_symporter PF03616.9 CDI80539.1 - 0.018 13.5 2.0 0.021 13.3 1.4 1.0 1 0 0 1 1 1 0 Sodium/glutamate symporter DUF4557 PF15101.1 CDI80539.1 - 0.018 14.8 12.3 0.019 14.8 8.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) VIT1 PF01988.14 CDI80539.1 - 0.03 13.7 4.1 0.036 13.5 2.8 1.1 1 0 0 1 1 1 0 VIT family DUF3357 PF11837.3 CDI80539.1 - 0.035 13.9 0.2 0.052 13.4 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) FHIPEP PF00771.15 CDI80539.1 - 0.036 12.3 4.2 0.037 12.3 2.9 1.0 1 0 0 1 1 1 0 FHIPEP family Med15 PF09606.5 CDI80539.1 - 0.042 12.0 33.3 0.046 11.9 23.1 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal MAPEG PF01124.13 CDI80539.1 - 0.048 13.2 2.4 0.06 12.9 1.7 1.2 1 0 0 1 1 1 0 MAPEG family Trp_oprn_chp PF09534.5 CDI80539.1 - 0.054 13.1 6.9 0.072 12.7 4.8 1.3 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Cyto_heme_lyase PF01265.12 CDI80539.1 - 0.063 12.8 6.7 0.066 12.7 4.6 1.0 1 0 0 1 1 1 0 Cytochrome c/c1 heme lyase SAGA-Tad1 PF12767.2 CDI80539.1 - 0.067 12.8 7.8 0.067 12.8 5.4 1.1 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit DUF533 PF04391.7 CDI80539.1 - 0.068 12.5 15.2 0.073 12.4 10.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF533) DUF2232 PF09991.4 CDI80539.1 - 0.069 12.1 2.3 0.082 11.8 1.6 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) DUF1071 PF06378.6 CDI80539.1 - 0.073 12.2 4.4 0.075 12.1 3.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1071) zf-DHHC PF01529.15 CDI80539.1 - 0.074 12.4 2.4 0.075 12.4 1.7 1.1 1 0 0 1 1 1 0 DHHC palmitoyltransferase DUF3767 PF12597.3 CDI80539.1 - 0.075 12.6 8.0 0.096 12.3 5.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3767) SAMP PF05924.6 CDI80539.1 - 0.079 12.1 0.1 0.15 11.2 0.0 1.3 1 0 0 1 1 1 0 SAMP Motif ATG2_CAD PF13329.1 CDI80539.1 - 0.082 12.4 3.2 0.11 12.0 2.2 1.1 1 0 0 1 1 1 0 Autophagy-related protein 2 CAD motif UPF0560 PF10577.4 CDI80539.1 - 0.11 10.7 11.1 0.097 10.9 7.7 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 FLO_LFY PF01698.11 CDI80539.1 - 0.12 11.2 5.5 0.13 11.1 3.8 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein Peptidase_S15 PF02129.13 CDI80539.1 - 0.12 11.7 6.7 0.13 11.6 4.6 1.0 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) ERF PF04404.7 CDI80539.1 - 0.12 11.9 12.2 0.13 11.8 8.5 1.2 1 0 0 1 1 1 0 ERF superfamily Serinc PF03348.10 CDI80539.1 - 0.12 11.0 5.8 0.13 10.9 4.0 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) DUF4199 PF13858.1 CDI80539.1 - 0.12 12.2 2.3 0.15 11.9 1.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) Gag_spuma PF03276.9 CDI80539.1 - 0.13 10.5 14.3 0.13 10.5 9.9 1.1 1 0 0 1 1 1 0 Spumavirus gag protein DUF2453 PF10507.4 CDI80539.1 - 0.14 12.0 2.5 0.17 11.7 1.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2453) RIC3 PF15361.1 CDI80539.1 - 0.15 12.3 6.8 0.15 12.2 4.7 1.2 1 0 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 HemX PF04375.9 CDI80539.1 - 0.15 10.6 18.1 0.17 10.4 12.5 1.0 1 0 0 1 1 1 0 HemX R_equi_Vir PF05526.6 CDI80539.1 - 0.15 11.6 9.2 0.17 11.4 6.4 1.0 1 0 0 1 1 1 0 Rhodococcus equi virulence-associated protein AIF_C PF14721.1 CDI80539.1 - 0.17 12.1 5.5 0.21 11.8 3.8 1.1 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term FCP1_C PF09309.5 CDI80539.1 - 0.19 11.0 8.8 0.24 10.6 6.1 1.2 1 0 0 1 1 1 0 FCP1, C-terminal PAT1 PF09770.4 CDI80539.1 - 0.23 9.6 20.9 0.19 9.9 14.5 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Hid1 PF12722.2 CDI80539.1 - 0.25 8.9 2.9 0.25 9.0 2.0 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein RbsD_FucU PF05025.8 CDI80539.1 - 0.28 11.4 3.7 0.4 11.0 2.6 1.3 1 0 0 1 1 1 0 RbsD / FucU transport protein family Zip PF02535.17 CDI80539.1 - 0.31 10.0 1.3 0.38 9.7 0.9 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter TCP PF03634.8 CDI80539.1 - 0.32 11.3 8.7 0.38 11.1 6.1 1.1 1 0 0 1 1 1 0 TCP family transcription factor Band_3_cyto PF07565.8 CDI80539.1 - 0.34 10.3 5.7 0.35 10.3 3.9 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain TMEM51 PF15345.1 CDI80539.1 - 0.48 10.0 6.5 0.49 10.0 4.5 1.2 1 0 0 1 1 1 0 Transmembrane protein 51 RR_TM4-6 PF06459.7 CDI80539.1 - 0.48 10.2 4.8 0.45 10.3 3.3 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF912 PF06024.7 CDI80539.1 - 0.48 10.4 5.3 0.72 9.9 3.7 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) G0-G1_switch_2 PF15103.1 CDI80539.1 - 0.54 10.5 6.1 0.65 10.2 4.2 1.2 1 0 0 1 1 1 0 G0/G1 switch protein 2 Pex16 PF08610.5 CDI80539.1 - 0.54 9.1 5.8 0.58 9.0 4.0 1.0 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) FAM176 PF14851.1 CDI80539.1 - 0.57 9.8 3.5 0.74 9.4 2.4 1.1 1 0 0 1 1 1 0 FAM176 family EIIBC-GUT_N PF03612.9 CDI80539.1 - 0.76 9.3 5.0 0.81 9.2 3.5 1.2 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus PP2C_2 PF13672.1 CDI80539.1 - 0.77 9.1 8.1 0.94 8.8 5.6 1.1 1 0 0 1 1 1 0 Protein phosphatase 2C DUF788 PF05620.6 CDI80539.1 - 0.87 9.4 7.3 1 9.2 5.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF788) DUF3450 PF11932.3 CDI80539.1 - 0.9 8.7 18.9 1.1 8.4 13.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF775 PF05603.7 CDI80539.1 - 1 8.8 8.9 1 8.8 6.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF775) MARCKS PF02063.12 CDI80539.1 - 1 9.1 14.4 1.2 8.9 10.0 1.0 1 0 0 1 1 1 0 MARCKS family Trypan_glycop_C PF10659.4 CDI80539.1 - 1.1 9.5 7.5 1.8 8.9 5.2 1.3 1 0 0 1 1 1 0 Trypanosome variant surface glycoprotein C-terminal domain SRRM_C PF15230.1 CDI80539.1 - 1.1 9.3 3.3 1.6 8.8 2.3 1.2 1 0 0 1 1 1 0 Serine/arginine repetitive matrix protein C-terminus TFIIA PF03153.8 CDI80539.1 - 1.1 9.0 20.6 1.2 8.9 14.3 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4179 PF13786.1 CDI80539.1 - 1.2 9.4 3.0 2 8.6 2.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4179) SHR3_chaperone PF08229.6 CDI80539.1 - 1.2 8.0 8.4 1.2 8.0 5.8 1.1 1 0 0 1 1 1 0 ER membrane protein SH3 CoA_transf_3 PF02515.12 CDI80539.1 - 1.7 7.8 10.5 2 7.6 7.3 1.1 1 0 0 1 1 1 0 CoA-transferase family III Kei1 PF08552.6 CDI80539.1 - 2 8.0 6.5 2.4 7.7 4.5 1.1 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 MDFI PF15316.1 CDI80539.1 - 2.2 8.2 6.0 2.5 8.0 4.2 1.1 1 0 0 1 1 1 0 MyoD family inhibitor Glyco_transf_15 PF01793.11 CDI80539.1 - 2.6 6.9 6.3 3 6.6 4.3 1.1 1 0 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase DUF2574 PF10836.3 CDI80539.1 - 2.6 7.8 5.3 4 7.2 3.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2574) IncA PF04156.9 CDI80539.1 - 3.5 7.1 19.9 5.9 6.4 13.8 1.3 1 1 0 1 1 1 0 IncA protein DUF3373 PF11853.3 CDI80539.1 - 7.3 4.9 8.4 8.6 4.7 5.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) CD20 PF04103.10 CDI80539.1 - 8.2 6.3 7.5 12 5.7 5.2 1.4 1 1 0 1 1 1 0 CD20-like family RAB3GAP2_N PF14655.1 CDI80539.1 - 8.9 5.1 13.7 15 4.4 9.5 1.4 1 1 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus PsbW PF07123.7 CDI80539.1 - 9.2 6.3 11.1 12 6.0 7.7 1.1 1 0 0 1 1 1 0 Photosystem II reaction centre W protein (PsbW) CAF-1_p150 PF11600.3 CDI80541.1 - 0.0025 17.2 34.1 0.0025 17.2 23.6 4.2 3 1 1 4 4 4 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal Ribosomal_60s PF00428.14 CDI80541.1 - 2.6 8.4 11.0 6.2 7.2 7.6 1.6 1 0 0 1 1 1 0 60s Acidic ribosomal protein SPX PF03105.14 CDI80543.1 - 0.12 12.1 15.6 0.13 11.9 10.8 1.0 1 0 0 1 1 1 0 SPX domain DUF2217 PF10265.4 CDI80543.1 - 0.26 9.9 17.1 0.36 9.5 11.8 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) DUF4603 PF15376.1 CDI80543.1 - 0.56 7.3 15.2 0.63 7.1 10.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) FUSC PF04632.7 CDI80543.1 - 0.57 8.5 19.4 0.69 8.2 13.5 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF3598 PF12204.3 CDI80543.1 - 0.96 8.6 14.7 1.2 8.2 10.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3598) Herpes_glycop_H PF02489.11 CDI80543.1 - 1.4 6.8 6.0 1.6 6.6 4.2 1.0 1 0 0 1 1 1 0 Herpesvirus glycoprotein H Ant_C PF05586.6 CDI80543.1 - 1.8 9.1 7.6 1.1 9.8 2.4 2.1 2 0 0 2 2 2 0 Anthrax receptor C-terminus region SR-25 PF10500.4 CDI80543.1 - 2.3 7.6 27.8 5.4 6.4 19.3 1.6 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein FAM60A PF15396.1 CDI80543.1 - 2.4 7.8 15.4 2.7 7.6 10.7 1.2 1 0 0 1 1 1 0 Protein Family FAM60A dsDNA_bind PF01984.15 CDI80543.1 - 2.7 8.0 27.9 2.6 8.0 11.6 2.4 2 0 0 2 2 2 0 Double-stranded DNA-binding domain DUF572 PF04502.8 CDI80543.1 - 2.8 7.0 20.1 3.5 6.7 13.9 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) DNA_pol_viral_N PF00242.12 CDI80543.1 - 2.8 6.8 22.2 3 6.7 15.4 1.0 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain Hamartin PF04388.7 CDI80543.1 - 3.1 6.3 19.5 3.7 6.1 13.5 1.0 1 0 0 1 1 1 0 Hamartin protein LpxK PF02606.9 CDI80543.1 - 3.5 6.4 10.5 5.2 5.9 7.3 1.3 1 0 0 1 1 1 0 Tetraacyldisaccharide-1-P 4'-kinase Sporozoite_P67 PF05642.6 CDI80543.1 - 4.4 5.0 17.7 5.3 4.7 12.3 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen CDC73 PF05179.9 CDI80543.1 - 4.5 6.5 13.6 5.7 6.1 9.4 1.3 1 0 0 1 1 1 0 RNA pol II accessory factor, Cdc73 family DUF4175 PF13779.1 CDI80543.1 - 5.2 4.6 36.7 6.7 4.2 25.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Mem_trans PF03547.13 CDI80543.1 - 6 5.0 8.2 6.7 4.9 5.7 1.2 1 0 0 1 1 1 0 Membrane transport protein Ndc1_Nup PF09531.5 CDI80543.1 - 8 4.7 20.7 7.9 4.7 14.3 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup FtsJ PF01728.14 CDI80551.1 - 1.4e-21 77.2 6.2 3.7e-20 72.6 3.5 2.7 1 1 0 1 1 1 1 FtsJ-like methyltransferase Hist_deacetyl PF00850.14 CDI80551.1 - 0.0012 18.1 0.0 0.0012 18.1 0.0 2.5 2 2 0 2 2 1 1 Histone deacetylase domain Med15 PF09606.5 CDI80551.1 - 0.0014 16.9 41.5 0.0014 16.9 28.8 2.3 2 1 0 2 2 2 1 ARC105 or Med15 subunit of Mediator complex non-fungal SpoIIIAH PF12685.2 CDI80551.1 - 0.003 17.1 8.9 0.003 17.1 6.2 4.1 4 0 0 4 4 4 1 SpoIIIAH-like protein IncA PF04156.9 CDI80551.1 - 0.0034 16.9 21.2 0.0034 16.9 14.7 3.8 4 0 0 4 4 3 1 IncA protein SID-1_RNA_chan PF13965.1 CDI80551.1 - 0.004 15.4 9.6 0.004 15.4 6.6 3.0 3 0 0 3 3 3 1 dsRNA-gated channel SID-1 Cytochrom_B_N PF00033.14 CDI80551.1 - 0.0055 16.0 1.1 0.06 12.6 0.2 2.1 2 0 0 2 2 2 1 Cytochrome b(N-terminal)/b6/petB ODV-E18 PF10717.4 CDI80551.1 - 0.0072 15.7 0.6 0.0072 15.7 0.4 4.0 3 1 0 3 3 2 1 Occlusion-derived virus envelope protein ODV-E18 DUF1510 PF07423.6 CDI80551.1 - 0.0074 15.6 11.3 0.0074 15.6 7.8 4.0 3 1 1 4 4 4 1 Protein of unknown function (DUF1510) Ni_hydr_CYTB PF01292.15 CDI80551.1 - 0.012 15.0 0.2 0.1 11.9 0.0 2.0 2 0 0 2 2 2 0 Prokaryotic cytochrome b561 FAM176 PF14851.1 CDI80551.1 - 0.013 15.1 4.9 0.013 15.1 3.4 4.3 3 2 2 5 5 4 0 FAM176 family OAD_gamma PF04277.8 CDI80551.1 - 0.037 14.4 0.3 0.037 14.4 0.2 5.2 4 2 0 4 4 2 0 Oxaloacetate decarboxylase, gamma chain SOBP PF15279.1 CDI80551.1 - 0.055 13.8 36.9 0.34 11.2 13.0 2.1 2 0 0 2 2 2 0 Sine oculis-binding protein SAPS PF04499.10 CDI80551.1 - 0.11 11.1 0.0 0.11 11.1 0.0 3.1 2 1 1 3 3 2 0 SIT4 phosphatase-associated protein Methyltransf_23 PF13489.1 CDI80551.1 - 0.15 11.7 4.4 1.7 8.3 0.0 2.7 2 1 0 2 2 2 0 Methyltransferase domain DUF1467 PF07330.7 CDI80551.1 - 0.96 9.2 7.4 2.2 8.1 2.7 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1467) ABC2_membrane_2 PF12679.2 CDI80551.1 - 3.1 6.5 12.6 4 6.2 4.9 2.4 2 0 0 2 2 2 0 ABC-2 family transporter protein CbiA PF01656.18 CDI80551.1 - 6.2 6.1 8.6 3.1 7.1 4.1 2.0 1 1 1 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain DUF607 PF04678.8 CDI80557.1 - 0.24 11.3 3.7 0.3 11.0 2.6 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF607 TFIIA PF03153.8 CDI80557.1 - 2.8 7.7 23.0 3.8 7.2 16.0 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Hamartin PF04388.7 CDI80557.1 - 3.3 6.2 10.0 3.7 6.1 6.9 1.1 1 0 0 1 1 1 0 Hamartin protein DUF2232 PF09991.4 CDI80558.1 - 0.016 14.2 3.1 0.019 13.9 2.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) UPF0182 PF03699.8 CDI80558.1 - 0.028 12.4 3.1 0.032 12.1 2.1 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0182) FimP PF09766.4 CDI80558.1 - 0.053 12.5 8.5 0.077 12.0 5.9 1.3 1 0 0 1 1 1 0 Fms-interacting protein Med15 PF09606.5 CDI80558.1 - 0.065 11.4 30.9 0.078 11.1 21.4 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal EphA2_TM PF14575.1 CDI80558.1 - 0.1 13.0 0.8 0.31 11.4 0.3 1.9 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain RLL PF10036.4 CDI80558.1 - 0.13 11.6 5.9 0.14 11.5 4.1 1.2 1 0 0 1 1 1 0 Putative carnitine deficiency-associated protein MarC PF01914.12 CDI80558.1 - 0.15 11.1 0.1 0.15 11.1 0.1 1.7 1 1 1 2 2 2 0 MarC family integral membrane protein MRF_C2 PF13888.1 CDI80558.1 - 0.16 11.7 1.9 0.21 11.4 1.3 1.3 1 0 0 1 1 1 0 Myelin gene regulatory factor C-terminal domain 2 bHLH-MYC_N PF14215.1 CDI80558.1 - 0.33 11.1 7.3 0.42 10.7 5.1 1.2 1 0 0 1 1 1 0 bHLH-MYC and R2R3-MYB transcription factors N-terminal Porph_ging PF09697.5 CDI80558.1 - 0.59 10.3 2.6 1.3 9.1 1.8 1.8 1 1 0 1 1 1 0 Protein of unknown function (Porph_ging) DUF1183 PF06682.7 CDI80558.1 - 0.61 9.6 10.5 0.65 9.5 7.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) DUF4342 PF14242.1 CDI80558.1 - 0.99 9.2 9.0 2.1 8.1 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4342) RAB3GAP2_N PF14655.1 CDI80558.1 - 1.1 8.1 12.3 0.6 9.0 7.6 1.4 1 1 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus FHIPEP PF00771.15 CDI80558.1 - 1.4 7.2 11.5 1.5 7.0 7.9 1.2 1 1 0 1 1 1 0 FHIPEP family Spt20 PF12090.3 CDI80558.1 - 2.1 7.6 10.3 0.11 11.8 3.8 1.4 2 0 0 2 2 2 0 Spt20 family FliP PF00813.15 CDI80558.1 - 4.1 7.0 5.0 4.7 6.8 3.5 1.1 1 0 0 1 1 1 0 FliP family Dicty_REP PF05086.7 CDI80558.1 - 4.9 4.7 10.1 5 4.7 7.0 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein SpaB_C PF14028.1 CDI80558.1 - 6.5 6.2 19.0 9.8 5.6 13.2 1.3 1 0 0 1 1 1 0 SpaB C-terminal domain CD20 PF04103.10 CDI80558.1 - 7 6.5 6.7 1.3 8.8 0.9 1.9 1 1 1 2 2 2 0 CD20-like family CAF-1_p150 PF11600.3 CDI80558.1 - 7.1 5.9 18.9 0.15 11.4 4.6 2.1 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal AAA_23 PF13476.1 CDI80569.1 - 0.018 15.4 21.4 0.029 14.7 14.8 1.4 1 0 0 1 1 1 0 AAA domain Macoilin PF09726.4 CDI80569.1 - 0.4 8.9 39.4 0.7 8.0 27.3 1.3 1 0 0 1 1 1 0 Transmembrane protein Ribosomal_60s PF00428.14 CDI80569.1 - 1.6 9.1 16.1 1.2 9.6 9.3 2.0 2 0 0 2 2 2 0 60s Acidic ribosomal protein PAT1 PF09770.4 CDI80569.1 - 9.2 4.3 58.5 12 3.9 40.5 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Actin PF00022.14 CDI80591.1 - 6.4e-30 103.8 17.0 2.3e-17 62.5 8.1 2.7 2 1 0 2 2 2 2 Actin BAF1_ABF1 PF04684.8 CDI80591.1 - 7.4e-05 21.7 18.0 7.4e-05 21.7 12.5 6.9 4 2 0 5 5 5 1 BAF1 / ABF1 chromatin reorganising factor NicO PF03824.11 CDI80591.1 - 0.7 9.1 12.6 3.5 6.8 0.3 2.4 2 0 0 2 2 2 0 High-affinity nickel-transport protein MFS_2 PF13347.1 CDI80591.1 - 0.89 7.8 3.2 13 4.0 0.1 2.4 2 0 0 2 2 2 0 MFS/sugar transport protein MIP-T3 PF10243.4 CDI80629.1 - 0.49 8.7 62.8 0.57 8.5 43.5 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 TT_ORF1 PF02956.9 CDI80629.1 - 1.5 7.1 23.9 2.7 6.3 16.6 1.4 1 0 0 1 1 1 0 TT viral orf 1 Daxx PF03344.10 CDI80629.1 - 4.8 5.5 52.9 6.5 5.1 36.7 1.2 1 0 0 1 1 1 0 Daxx Family DUF755 PF05501.6 CDI80654.1 - 0.013 15.5 16.3 0.013 15.5 11.3 9.0 8 1 0 8 8 8 0 Domain of unknown function (DUF755) DUF3915 PF13054.1 CDI80654.1 - 2.4 8.1 0.0 2.4 8.1 0.0 4.2 4 0 0 4 4 4 0 Protein of unknown function (DUF3915) DUF45 PF01863.12 CDI80660.1 - 1.2 8.8 10.1 1.8 8.2 7.0 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF45 LAM_C PF12544.3 CDI80660.1 - 1.7 8.7 6.9 3 7.8 4.8 1.4 1 0 0 1 1 1 0 Lysine-2,3-aminomutase Mem_trans PF03547.13 CDI80678.1 - 4.4 5.4 0.0 4.4 5.4 0.0 7.1 6 2 0 6 6 6 0 Membrane transport protein DUF4647 PF15504.1 CDI80681.1 - 0.00095 18.1 11.5 0.0015 17.4 8.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4647) Pkinase PF00069.20 CDI80681.1 - 0.0021 17.2 7.1 0.066 12.3 3.7 2.9 2 1 0 2 2 2 1 Protein kinase domain RNA_lig_T4_1 PF09511.5 CDI80681.1 - 0.037 13.5 3.1 0.054 12.9 2.1 1.3 1 0 0 1 1 1 0 RNA ligase DivIC PF04977.10 CDI80681.1 - 0.078 12.4 22.2 0.31 10.5 4.9 2.3 2 0 0 2 2 2 0 Septum formation initiator AAA_23 PF13476.1 CDI80681.1 - 0.08 13.2 15.3 0.11 12.7 10.6 1.2 1 0 0 1 1 1 0 AAA domain 7TM_transglut PF14402.1 CDI80681.1 - 1.9 7.3 6.2 3 6.6 4.3 1.2 1 0 0 1 1 1 0 7 transmembrane helices usually fused to an inactive transglutaminase PHD_3 PF13922.1 CDI80681.1 - 7.9 6.8 21.8 0.41 10.9 2.4 3.0 3 1 0 3 3 3 0 PHD domain of transcriptional enhancer, Asx RLL PF10036.4 CDI80684.1 - 5.3e-14 52.2 10.5 1.9e-13 50.4 7.3 1.8 1 1 0 1 1 1 1 Putative carnitine deficiency-associated protein Ndc1_Nup PF09531.5 CDI80684.1 - 0.21 9.9 1.4 0.24 9.7 1.0 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup RAB3GAP2_N PF14655.1 CDI80684.1 - 0.56 9.1 6.1 0.77 8.6 1.6 2.0 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus DUF1071 PF06378.6 CDI80684.1 - 8.5 5.4 7.1 25 3.9 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1071) DNA_ligase_aden PF01653.13 CDI80691.1 - 2e-05 23.6 1.9 2.7e-05 23.2 0.2 2.0 2 1 0 2 2 2 1 NAD-dependent DNA ligase adenylation domain FimP PF09766.4 CDI80691.1 - 0.00062 18.9 20.2 0.0014 17.7 1.6 2.2 2 0 0 2 2 2 2 Fms-interacting protein ARF7EP_C PF14949.1 CDI80691.1 - 0.0096 16.3 0.4 0.0096 16.3 0.2 3.3 3 1 1 4 4 4 1 ARF7 effector protein C-terminus MAT1 PF06391.8 CDI80691.1 - 0.31 10.5 14.4 0.17 11.4 0.6 2.3 2 0 0 2 2 2 0 CDK-activating kinase assembly factor MAT1 RAB3GAP2_N PF14655.1 CDI80691.1 - 0.35 9.8 21.7 0.37 9.7 4.9 2.6 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus DUF4355 PF14265.1 CDI80691.1 - 1.6 8.6 23.0 0.16 11.8 3.8 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4355) CAF-1_p150 PF11600.3 CDI80691.1 - 3.7 6.8 50.3 0.39 10.0 15.6 3.3 3 0 0 3 3 3 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal OMPdecase PF00215.19 CDI80691.1 - 6.7 6.0 11.3 3.2 7.0 3.1 2.3 2 0 0 2 2 2 0 Orotidine 5'-phosphate decarboxylase / HUMPS family DUF3801 PF12687.2 CDI80692.1 - 0.2 11.2 43.6 0.097 12.2 0.8 3.6 3 1 0 3 3 3 0 Protein of unknown function (DUF3801) TMEM164 PF14808.1 CDI80692.1 - 4.9 6.2 5.8 2.4 7.2 0.1 2.7 3 0 0 3 3 3 0 TMEM164 family DUF1510 PF07423.6 CDI80698.1 - 0.00097 18.5 7.8 0.00097 18.5 5.4 2.1 1 1 0 2 2 2 1 Protein of unknown function (DUF1510) IncA PF04156.9 CDI80698.1 - 0.0094 15.5 14.3 0.0094 15.5 9.9 2.3 1 1 1 2 2 2 1 IncA protein DUF3357 PF11837.3 CDI80698.1 - 0.049 13.4 0.3 0.049 13.4 0.2 3.1 1 1 1 3 3 3 0 Domain of unknown function (DUF3357) DUF572 PF04502.8 CDI80698.1 - 0.054 12.7 24.4 0.068 12.3 16.9 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Otopetrin PF03189.8 CDI80698.1 - 0.078 11.9 8.9 0.097 11.6 6.2 1.0 1 0 0 1 1 1 0 Otopetrin DUF2149 PF09919.4 CDI80698.1 - 0.1 12.7 11.8 0.055 13.5 1.5 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2149) DUF3334 PF11813.3 CDI80698.1 - 0.17 11.3 11.0 0.88 9.0 0.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3334) EphA2_TM PF14575.1 CDI80698.1 - 0.26 11.6 15.9 2.7 8.4 5.0 2.9 2 1 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain GRP PF07172.6 CDI80698.1 - 0.33 11.4 8.4 0.14 12.6 1.6 2.3 2 1 0 2 2 2 0 Glycine rich protein family DUF1632 PF07857.7 CDI80698.1 - 0.43 9.7 3.3 0.16 11.2 0.2 1.7 2 0 0 2 2 2 0 CEO family (DUF1632) FAM176 PF14851.1 CDI80698.1 - 0.5 10.0 7.6 0.74 9.4 0.5 2.4 2 0 0 2 2 2 0 FAM176 family TRAUB PF08164.7 CDI80698.1 - 1 9.4 12.9 0.044 13.8 1.4 2.4 2 0 0 2 2 2 0 Apoptosis-antagonizing transcription factor, C-terminal DUF966 PF06136.8 CDI80698.1 - 1.1 8.6 21.0 1.6 8.0 14.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF966) DUF2217 PF10265.4 CDI80698.1 - 2 7.1 18.8 2.3 6.8 13.0 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) DUF2140 PF09911.4 CDI80698.1 - 2.4 7.3 8.0 1.1 8.4 1.0 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2140) MSP1_C PF07462.6 CDI80698.1 - 4.4 5.5 12.9 6.7 4.9 8.9 1.3 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Claudin_2 PF13903.1 CDI80698.1 - 4.4 6.9 28.0 0.088 12.4 8.7 2.1 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction CD20 PF04103.10 CDI80698.1 - 7.3 6.5 12.7 3.9 7.4 0.8 2.5 1 1 0 2 2 2 0 CD20-like family Tetraspannin PF00335.15 CDI80698.1 - 9.6 5.4 12.0 0.86 8.8 2.3 2.1 1 1 0 2 2 2 0 Tetraspanin family Herpes_LMP1 PF05297.6 CDI80699.1 - 0.2 10.5 0.6 0.38 9.6 0.4 1.4 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) LMBR1 PF04791.11 CDI80699.1 - 0.21 10.1 0.0 0.21 10.1 0.0 3.1 1 1 1 3 3 3 0 LMBR1-like membrane protein DUF814 PF05670.8 CDI80700.1 - 4.9e-18 64.7 0.7 4.9e-18 64.7 0.5 3.8 2 1 0 2 2 2 1 Domain of unknown function (DUF814) Herpes_DNAp_acc PF04929.7 CDI80700.1 - 0.00098 18.1 7.6 0.00098 18.1 5.3 9.5 5 4 3 8 8 8 2 Herpes DNA replication accessory factor EF-hand_1 PF00036.27 CDI80709.1 - 0.1 11.9 0.0 0.21 10.9 0.0 1.4 1 0 0 1 1 1 0 EF hand EF-hand_5 PF13202.1 CDI80709.1 - 0.18 11.2 0.0 0.34 10.3 0.0 1.4 1 0 0 1 1 1 0 EF hand FimP PF09766.4 CDI80713.1 - 0.098 11.7 24.4 0.11 11.4 16.9 1.1 1 0 0 1 1 1 0 Fms-interacting protein Pex14_N PF04695.8 CDI80713.1 - 0.22 11.5 21.0 0.25 11.3 14.6 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region TMEM51 PF15345.1 CDI80713.1 - 0.43 10.2 13.2 0.44 10.1 9.2 1.3 1 0 0 1 1 1 0 Transmembrane protein 51 Baculo_PP31 PF05311.6 CDI80713.1 - 0.63 9.2 13.2 0.66 9.1 9.2 1.2 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) CPSF100_C PF13299.1 CDI80713.1 - 0.79 9.8 13.2 0.97 9.6 9.1 1.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Herpes_DNAp_acc PF04929.7 CDI80713.1 - 1.3 7.8 12.7 1.5 7.6 8.8 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor SprA-related PF12118.3 CDI80713.1 - 1.6 8.0 35.8 1.8 7.7 24.8 1.1 1 0 0 1 1 1 0 SprA-related family Peptidase_S49_N PF08496.5 CDI80713.1 - 2 8.2 18.6 2.4 7.9 12.9 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Serinc PF03348.10 CDI80713.1 - 2.1 6.9 12.2 2.2 6.8 8.4 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) zf-DHHC PF01529.15 CDI80713.1 - 3 7.1 6.9 3.5 6.9 4.8 1.3 1 0 0 1 1 1 0 DHHC palmitoyltransferase RR_TM4-6 PF06459.7 CDI80713.1 - 3.1 7.5 12.0 3.4 7.4 8.3 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Peptidase_U57 PF05582.7 CDI80713.1 - 3.4 6.5 10.8 3.6 6.4 7.5 1.1 1 0 0 1 1 1 0 YabG peptidase U57 DUF1266 PF06889.6 CDI80713.1 - 3.9 7.2 11.3 4.4 7.0 7.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1266) DUF4407 PF14362.1 CDI80713.1 - 4.2 6.2 18.6 4.4 6.1 12.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Endonuc_Holl PF10107.4 CDI80713.1 - 4.2 7.0 14.3 6.7 6.3 9.9 1.3 1 0 0 1 1 1 0 Endonuclease related to archaeal Holliday junction resolvase eIF-3_zeta PF05091.7 CDI80713.1 - 4.5 5.7 21.0 4.4 5.8 14.6 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) SAGA-Tad1 PF12767.2 CDI80713.1 - 5.4 6.5 23.8 6 6.4 16.5 1.0 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit AUX_IAA PF02309.11 CDI80713.1 - 6.6 6.4 12.2 7.6 6.2 8.5 1.2 1 0 0 1 1 1 0 AUX/IAA family FLO_LFY PF01698.11 CDI80713.1 - 6.7 5.4 17.2 7.9 5.2 11.9 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein Gag_spuma PF03276.9 CDI80713.1 - 7.1 4.8 28.4 6.9 4.8 19.7 1.1 1 0 0 1 1 1 0 Spumavirus gag protein Kei1 PF08552.6 CDI80713.1 - 7.2 6.2 7.9 7.2 6.2 5.5 1.2 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 DDHD PF02862.12 CDI80713.1 - 7.6 6.2 14.9 8.6 6.0 10.4 1.0 1 0 0 1 1 1 0 DDHD domain EIIBC-GUT_N PF03612.9 CDI80713.1 - 7.7 6.0 10.1 8.6 5.9 7.0 1.3 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus PAT1 PF09770.4 CDI80713.1 - 8.4 4.4 40.1 8.7 4.4 27.8 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Folliculin PF11704.3 CDI80713.1 - 8.6 5.9 11.3 11 5.5 7.8 1.2 1 0 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport Endonuc-BglII PF09195.6 CDI80713.1 - 8.9 5.7 10.1 12 5.3 7.0 1.2 1 0 0 1 1 1 0 Restriction endonuclease BglII FAM60A PF15396.1 CDI80713.1 - 9.8 5.8 12.6 12 5.5 8.7 1.1 1 0 0 1 1 1 0 Protein Family FAM60A CAF-1_p150 PF11600.3 CDI80725.1 - 0.008 15.5 42.4 0.0082 15.5 29.4 1.1 1 0 0 1 1 1 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal AMP-binding PF00501.23 CDI80725.1 - 0.01 14.2 8.3 0.015 13.6 5.7 1.3 1 0 0 1 1 1 0 AMP-binding enzyme DUF1510 PF07423.6 CDI80725.1 - 0.24 10.7 39.4 0.28 10.5 27.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Raftlin PF15250.1 CDI80725.1 - 1.3 7.4 30.2 1.5 7.2 21.0 1.3 1 0 0 1 1 1 0 Raftlin Mem_trans PF03547.13 CDI80725.1 - 1.8 6.7 17.3 2 6.6 12.0 1.1 1 0 0 1 1 1 0 Membrane transport protein U79_P34 PF03064.11 CDI80725.1 - 2 7.8 29.3 2.5 7.5 20.3 1.2 1 0 0 1 1 1 0 HSV U79 / HCMV P34 SID-1_RNA_chan PF13965.1 CDI80725.1 - 2.4 6.2 20.3 2.5 6.1 14.1 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DHHW PF14286.1 CDI80725.1 - 2.4 7.3 28.7 2.5 7.3 19.9 1.2 1 0 0 1 1 1 0 DHHW protein BTV_NS2 PF04514.7 CDI80725.1 - 2.8 6.7 26.4 3.3 6.5 18.3 1.3 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Asp-B-Hydro_N PF05279.6 CDI80725.1 - 4.2 7.1 31.0 4.4 7.0 21.5 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Pilt PF15453.1 CDI80725.1 - 4.9 6.7 35.7 5.6 6.5 24.7 1.0 1 0 0 1 1 1 0 Protein incorporated later into Tight Junctions PCEMA1 PF07418.6 CDI80725.1 - 7.1 5.9 21.3 7.5 5.8 14.8 1.1 1 0 0 1 1 1 0 Acidic phosphoprotein precursor PCEMA1 Med15 PF09606.5 CDI80725.1 - 7.7 4.5 108.9 9 4.3 75.5 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal PAT1 PF09770.4 CDI80725.1 - 9.3 4.3 79.7 9.6 4.2 55.2 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 IncA PF04156.9 CDI80726.1 - 0.011 15.2 9.5 0.011 15.2 6.6 2.6 4 0 0 4 4 2 0 IncA protein Spt20 PF12090.3 CDI80726.1 - 0.028 13.7 3.7 0.041 13.2 2.5 1.3 1 0 0 1 1 1 0 Spt20 family Macoilin PF09726.4 CDI80726.1 - 0.03 12.6 13.5 0.032 12.5 9.3 1.1 1 0 0 1 1 1 0 Transmembrane protein DUF3984 PF13136.1 CDI80726.1 - 0.038 13.2 13.3 0.049 12.8 9.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3984) Peptidase_S49_N PF08496.5 CDI80726.1 - 0.047 13.4 5.6 0.073 12.8 3.9 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal HD-ZIP_N PF04618.7 CDI80726.1 - 0.19 12.2 4.9 0.42 11.1 3.4 1.6 1 0 0 1 1 1 0 HD-ZIP protein N terminus ERF PF04404.7 CDI80726.1 - 0.19 11.2 8.5 0.33 10.4 5.9 1.4 1 0 0 1 1 1 0 ERF superfamily DDHD PF02862.12 CDI80726.1 - 0.45 10.2 6.8 0.59 9.8 4.7 1.3 1 0 0 1 1 1 0 DDHD domain SOBP PF15279.1 CDI80726.1 - 0.9 9.8 20.7 1.4 9.2 14.3 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein DUF912 PF06024.7 CDI80726.1 - 1.8 8.6 4.1 3.7 7.6 2.8 1.5 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Otopetrin PF03189.8 CDI80726.1 - 2 7.3 4.6 2.3 7.1 3.2 1.1 1 0 0 1 1 1 0 Otopetrin Hid1 PF12722.2 CDI80726.1 - 2.1 5.9 7.6 2.3 5.7 5.3 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Neur_chan_memb PF02932.11 CDI80726.1 - 2.1 8.1 5.6 2.6 7.8 3.9 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF2215 PF10225.4 CDI80726.1 - 2.5 7.4 4.6 3.7 6.9 3.2 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) DivIC PF04977.10 CDI80726.1 - 6.6 6.2 12.9 1.9 8.0 6.8 1.6 2 0 0 2 2 2 0 Septum formation initiator DUF2217 PF10265.4 CDI80726.1 - 9.5 4.8 13.0 13 4.4 9.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) BAF1_ABF1 PF04684.8 CDI80740.1 - 0.00045 19.2 14.7 0.00045 19.2 10.2 25.0 12 4 9 25 25 25 4 BAF1 / ABF1 chromatin reorganising factor SAPS PF04499.10 CDI80740.1 - 0.68 8.5 0.0 0.68 8.5 0.0 9.5 8 3 1 9 9 9 0 SIT4 phosphatase-associated protein CAF-1_p150 PF11600.3 CDI80743.1 - 0.0036 16.7 15.6 0.0039 16.5 10.8 1.1 1 0 0 1 1 1 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal Spore_coat_CotO PF14153.1 CDI80743.1 - 0.047 13.1 19.4 0.048 13.0 13.5 1.2 1 0 0 1 1 1 0 Spore coat protein CotO SelP_N PF04592.9 CDI80743.1 - 0.13 11.6 14.3 0.14 11.5 9.9 1.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region NPR3 PF03666.8 CDI80743.1 - 0.15 10.5 11.6 0.15 10.5 8.0 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Med15 PF09606.5 CDI80743.1 - 0.16 10.1 56.6 0.19 9.9 39.2 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal CDC45 PF02724.9 CDI80743.1 - 0.16 9.9 10.2 0.18 9.8 7.1 1.2 1 0 0 1 1 1 0 CDC45-like protein PPP4R2 PF09184.6 CDI80743.1 - 0.17 11.4 11.1 0.18 11.3 7.7 1.1 1 0 0 1 1 1 0 PPP4R2 Baculo_PP31 PF05311.6 CDI80743.1 - 0.19 10.9 13.5 0.2 10.8 9.4 1.2 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) eIF-3_zeta PF05091.7 CDI80743.1 - 0.25 9.9 19.2 0.24 9.9 13.3 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) FLO_LFY PF01698.11 CDI80743.1 - 0.26 10.0 15.3 0.29 9.9 10.6 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein FHIPEP PF00771.15 CDI80743.1 - 0.34 9.1 11.3 0.42 8.8 7.8 1.1 1 0 0 1 1 1 0 FHIPEP family Peptidase_S49_N PF08496.5 CDI80743.1 - 0.44 10.3 11.2 0.55 10.0 7.8 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal RR_TM4-6 PF06459.7 CDI80743.1 - 0.45 10.3 17.6 0.51 10.1 12.2 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 PAT1 PF09770.4 CDI80743.1 - 0.52 8.4 46.6 0.59 8.2 32.3 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Serinc PF03348.10 CDI80743.1 - 0.52 8.9 14.4 0.55 8.8 9.9 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) Raftlin PF15250.1 CDI80743.1 - 0.58 8.6 15.5 0.62 8.5 10.7 1.0 1 0 0 1 1 1 0 Raftlin DUF2126 PF09899.4 CDI80743.1 - 0.64 7.9 11.8 0.69 7.8 8.2 1.1 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) DDHD PF02862.12 CDI80743.1 - 0.64 9.7 14.9 0.72 9.6 10.3 1.2 1 0 0 1 1 1 0 DDHD domain GAGA_bind PF06217.7 CDI80743.1 - 0.68 9.8 16.1 0.73 9.7 11.2 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family SprA-related PF12118.3 CDI80743.1 - 0.72 9.1 48.0 1.1 8.5 33.3 1.2 1 0 0 1 1 1 0 SprA-related family UPF0560 PF10577.4 CDI80743.1 - 0.73 8.0 22.9 0.71 8.0 15.9 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 AAA_23 PF13476.1 CDI80743.1 - 0.9 9.8 15.8 0.94 9.7 11.0 1.1 1 0 0 1 1 1 0 AAA domain DUF4603 PF15376.1 CDI80743.1 - 0.94 6.5 11.7 1.1 6.3 8.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) PBP_sp32 PF07222.7 CDI80743.1 - 0.97 8.5 18.5 1.2 8.2 12.8 1.2 1 0 0 1 1 1 0 Proacrosin binding protein sp32 DUF3381 PF11861.3 CDI80743.1 - 0.97 8.9 15.0 1.2 8.6 10.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) Tim54 PF11711.3 CDI80743.1 - 1.1 7.7 12.5 1.1 7.7 8.6 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 NARP1 PF12569.3 CDI80743.1 - 1.2 7.8 21.1 1.4 7.5 14.6 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DUF4045 PF13254.1 CDI80743.1 - 1.3 8.2 16.9 1.6 7.8 11.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) FAM60A PF15396.1 CDI80743.1 - 1.4 8.5 12.6 1.6 8.4 8.7 1.2 1 0 0 1 1 1 0 Protein Family FAM60A SAGA-Tad1 PF12767.2 CDI80743.1 - 1.5 8.4 18.8 1.7 8.2 13.0 1.1 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit Lin-8 PF03353.10 CDI80743.1 - 2 7.6 18.8 2.2 7.5 13.0 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Sec62 PF03839.11 CDI80743.1 - 2.2 7.6 9.7 2.4 7.5 6.7 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 CDK5_activator PF03261.10 CDI80743.1 - 2.2 7.5 15.5 3 7.1 10.7 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein Cellulose_synt PF03552.9 CDI80743.1 - 2.5 6.3 6.4 2.6 6.2 4.5 1.0 1 0 0 1 1 1 0 Cellulose synthase DUF2215 PF10225.4 CDI80743.1 - 2.5 7.4 7.6 2.7 7.3 5.2 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) DUF4220 PF13968.1 CDI80743.1 - 2.8 6.9 6.0 2.6 7.0 4.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4220) OATP PF03137.15 CDI80743.1 - 3 5.7 11.5 3.3 5.6 7.9 1.2 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family DUF4228 PF14009.1 CDI80743.1 - 3 7.9 15.3 4.4 7.4 10.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4228) Ycf1 PF05758.7 CDI80743.1 - 3 5.4 16.5 3.4 5.2 11.4 1.0 1 0 0 1 1 1 0 Ycf1 Exonuc_VII_L PF02601.10 CDI80743.1 - 4.5 6.3 18.9 5.9 5.9 13.1 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Hid1 PF12722.2 CDI80743.1 - 4.9 4.7 18.6 5.7 4.4 12.9 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Hamartin PF04388.7 CDI80743.1 - 5.2 5.6 18.5 5.8 5.4 12.8 1.0 1 0 0 1 1 1 0 Hamartin protein Ndc1_Nup PF09531.5 CDI80743.1 - 5.3 5.3 13.9 4.7 5.5 9.6 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Peptidase_U57 PF05582.7 CDI80743.1 - 5.4 5.9 12.8 6.8 5.5 8.9 1.1 1 0 0 1 1 1 0 YabG peptidase U57 Neur_chan_memb PF02932.11 CDI80743.1 - 5.5 6.8 12.0 6 6.6 8.3 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region SID-1_RNA_chan PF13965.1 CDI80743.1 - 5.7 4.9 8.6 5.9 4.9 5.9 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Band_3_cyto PF07565.8 CDI80743.1 - 6.5 6.1 18.7 8.5 5.8 13.0 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain DUF3449 PF11931.3 CDI80743.1 - 7 6.1 18.1 9.5 5.6 12.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3449) DUF913 PF06025.7 CDI80743.1 - 7.7 5.1 13.0 8.4 5.0 9.0 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) PBP1_TM PF14812.1 CDI80743.1 - 8 6.8 9.2 12 6.3 6.4 1.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Paramyxo_ncap PF00973.14 CDI80743.1 - 8.7 4.9 14.7 9.2 4.8 10.2 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Na_Ca_ex PF01699.19 CDI80749.1 - 0.015 14.9 0.4 0.019 14.5 0.3 1.1 1 0 0 1 1 1 0 Sodium/calcium exchanger protein Yip1 PF04893.12 CDI80749.1 - 0.019 14.4 4.9 0.025 14.1 3.4 1.1 1 0 0 1 1 1 0 Yip1 domain MASE1 PF05231.9 CDI80749.1 - 0.031 13.3 6.8 0.037 13.0 4.7 1.0 1 0 0 1 1 1 0 MASE1 IncA PF04156.9 CDI80749.1 - 0.049 13.2 0.2 0.059 12.9 0.1 1.2 1 0 0 1 1 1 0 IncA protein DUF1129 PF06570.6 CDI80749.1 - 0.071 12.4 0.1 0.092 12.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) Rifin_STEVOR PF02009.11 CDI80749.1 - 1.7 8.2 8.8 2.7 7.5 6.1 1.3 1 0 0 1 1 1 0 Rifin/stevor family Gate PF07670.9 CDI80749.1 - 3.2 7.6 9.8 10 6.0 6.0 1.9 2 0 0 2 2 2 0 Nucleoside recognition SGT1 PF07093.6 CDI80761.1 - 9.8e-05 20.9 9.3 0.00012 20.5 6.5 1.2 1 0 0 1 1 1 1 SGT1 protein DUF4045 PF13254.1 CDI80761.1 - 0.055 12.7 8.1 0.11 11.7 5.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Daxx PF03344.10 CDI80761.1 - 0.11 10.9 15.5 0.19 10.2 10.7 1.3 1 0 0 1 1 1 0 Daxx Family Neur_chan_memb PF02932.11 CDI80761.1 - 0.39 10.5 7.7 0.64 9.8 5.4 1.5 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Ndc1_Nup PF09531.5 CDI80761.1 - 0.71 8.2 10.5 1 7.7 7.3 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup CDC45 PF02724.9 CDI80761.1 - 0.99 7.3 13.2 1.5 6.8 9.1 1.2 1 0 0 1 1 1 0 CDC45-like protein Med15 PF09606.5 CDI80761.1 - 1 7.4 77.7 0.052 11.7 49.5 1.8 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal eIF-3_zeta PF05091.7 CDI80761.1 - 5.8 5.4 18.0 9.3 4.7 12.5 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) HSBP1 PF06825.7 CDI80781.1 - 2.4e-10 39.8 0.3 5.1e-10 38.7 0.2 1.5 1 0 0 1 1 1 1 Heat shock factor binding protein 1 Sporozoite_P67 PF05642.6 CDI80781.1 - 0.27 9.0 14.8 0.025 12.4 2.1 2.1 2 0 0 2 2 2 0 Sporozoite P67 surface antigen Zip PF02535.17 CDI80781.1 - 0.28 10.1 6.0 1.4 7.8 2.6 2.4 2 0 0 2 2 2 0 ZIP Zinc transporter Herpes_UL87 PF03043.9 CDI80781.1 - 0.32 9.3 8.0 0.53 8.6 5.5 1.6 1 1 0 1 1 1 0 Herpesvirus UL87 family DNA_pol_viral_N PF00242.12 CDI80781.1 - 2.3 7.1 25.7 0.98 8.3 4.8 2.2 2 0 0 2 2 2 0 DNA polymerase (viral) N-terminal domain Mem_trans PF03547.13 CDI80781.1 - 4.9 5.3 8.6 0.68 8.1 0.5 2.2 2 0 0 2 2 2 0 Membrane transport protein FAM60A PF15396.1 CDI80781.1 - 8.2 6.1 25.9 2 8.1 7.3 2.4 2 1 0 2 2 2 0 Protein Family FAM60A ODV-E18 PF10717.4 CDI80783.1 - 0.068 12.6 0.6 0.3 10.5 0.4 2.2 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 Bap31 PF05529.7 CDI80783.1 - 0.15 11.5 0.2 0.35 10.2 0.2 1.7 1 1 0 1 1 1 0 B-cell receptor-associated protein 31-like DUF179 PF02622.10 CDI80802.1 - 8.3e-08 32.0 5.2 6.5e-05 22.6 0.7 3.0 2 1 0 2 2 2 2 Uncharacterized ACR, COG1678 zf-DHHC PF01529.15 CDI80802.1 - 0.14 11.5 4.5 2.4 7.5 1.7 2.5 2 0 0 2 2 2 0 DHHC palmitoyltransferase RRM_1 PF00076.17 CDI80803.1 - 4.1e-08 32.7 0.0 7e-08 31.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CDI80803.1 - 0.0014 18.5 0.0 0.0026 17.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) SR-25 PF10500.4 CDI80803.1 - 0.0047 16.4 29.8 0.008 15.6 20.7 1.4 1 1 0 1 1 1 1 Nuclear RNA-splicing-associated protein DUF1635 PF07795.6 CDI80803.1 - 0.045 13.1 8.0 0.33 10.2 4.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1635) NID PF07292.8 CDI80803.1 - 0.098 12.7 0.0 9 6.4 0.0 2.4 2 0 0 2 2 2 0 Nmi/IFP 35 domain (NID) DUF2215 PF10225.4 CDI80803.1 - 2.6 7.4 4.5 3.7 6.9 3.2 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) TFIIA PF03153.8 CDI80803.1 - 2.7 7.8 21.1 3.5 7.4 14.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PAP1 PF08601.5 CDI80803.1 - 3 7.4 17.2 3.9 7.0 11.9 1.2 1 0 0 1 1 1 0 Transcription factor PAP1 BAF1_ABF1 PF04684.8 CDI80805.1 - 0.0004 19.3 14.2 0.0004 19.3 9.9 8.9 7 2 2 9 9 9 2 BAF1 / ABF1 chromatin reorganising factor zf-C4_ClpX PF06689.8 CDI80807.1 - 0.022 14.2 3.3 0.039 13.4 2.3 1.3 1 0 0 1 1 1 0 ClpX C4-type zinc finger Spt20 PF12090.3 CDI80807.1 - 0.92 8.8 3.7 1.4 8.2 2.6 1.2 1 0 0 1 1 1 0 Spt20 family Podoplanin PF05808.6 CDI80810.1 - 0.047 13.2 0.2 0.055 13.0 0.1 1.1 1 0 0 1 1 1 0 Podoplanin Med15 PF09606.5 CDI80814.1 - 0.057 11.6 113.6 0.075 11.2 78.7 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal ETRAMP PF09716.5 CDI80814.1 - 0.059 13.3 9.9 14 5.7 6.9 3.5 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) GAGA_bind PF06217.7 CDI80814.1 - 0.16 11.9 45.5 0.26 11.2 31.5 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family CDC27 PF09507.5 CDI80814.1 - 0.23 10.6 53.6 0.3 10.2 37.2 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 PAT1 PF09770.4 CDI80814.1 - 0.95 7.6 98.4 1.2 7.2 68.2 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SSP160 PF06933.6 CDI80814.1 - 1.1 7.1 13.2 1.4 6.8 9.2 1.0 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Dehydrin PF00257.14 CDI80823.1 - 0.0068 16.7 7.9 0.014 15.7 5.4 1.6 1 0 0 1 1 1 1 Dehydrin UPF0560 PF10577.4 CDI80823.1 - 0.0082 14.4 7.8 0.0086 14.4 5.4 1.2 1 0 0 1 1 1 1 Uncharacterised protein family UPF0560 TFIIF_alpha PF05793.7 CDI80823.1 - 0.032 12.6 10.3 0.038 12.3 7.2 1.0 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF4647 PF15504.1 CDI80823.1 - 0.038 12.8 8.4 0.04 12.7 5.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4647) CDC45 PF02724.9 CDI80823.1 - 0.059 11.3 7.6 0.062 11.3 5.3 1.1 1 0 0 1 1 1 0 CDC45-like protein Hid1 PF12722.2 CDI80823.1 - 0.084 10.5 10.1 0.085 10.5 7.0 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Spt20 PF12090.3 CDI80823.1 - 0.092 12.0 6.9 0.12 11.7 4.8 1.3 1 0 0 1 1 1 0 Spt20 family Macoilin PF09726.4 CDI80823.1 - 0.13 10.4 19.8 0.17 10.1 13.7 1.1 1 0 0 1 1 1 0 Transmembrane protein FimP PF09766.4 CDI80823.1 - 0.14 11.1 13.4 0.18 10.8 9.3 1.1 1 0 0 1 1 1 0 Fms-interacting protein DUF572 PF04502.8 CDI80823.1 - 0.19 10.9 15.7 0.23 10.6 10.8 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Plasmodium_Vir PF05795.6 CDI80823.1 - 0.34 10.0 5.0 0.42 9.7 3.5 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein DUF3573 PF12097.3 CDI80823.1 - 0.45 9.0 7.4 0.54 8.8 5.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) Neur_chan_memb PF02932.11 CDI80823.1 - 0.52 10.1 7.1 0.63 9.8 4.9 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Ycf1 PF05758.7 CDI80823.1 - 0.64 7.6 5.9 0.69 7.5 4.1 1.0 1 0 0 1 1 1 0 Ycf1 PLRV_ORF5 PF01690.12 CDI80823.1 - 0.86 8.6 14.3 1 8.4 9.9 1.0 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Paramyxo_ncap PF00973.14 CDI80823.1 - 0.97 8.0 9.1 1.1 7.9 6.3 1.2 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein CDC73 PF05179.9 CDI80823.1 - 1.4 8.2 12.4 1.7 7.9 8.6 1.3 1 1 0 1 1 1 0 RNA pol II accessory factor, Cdc73 family NPR3 PF03666.8 CDI80823.1 - 1.6 7.1 13.1 2.1 6.7 9.1 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF2681 PF10883.3 CDI80823.1 - 1.7 8.9 15.6 5.4 7.3 10.8 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) Herpes_env PF01673.13 CDI80823.1 - 2.1 6.8 17.2 2.4 6.5 11.9 1.0 1 0 0 1 1 1 0 Herpesvirus putative major envelope glycoprotein Hep_59 PF07052.6 CDI80823.1 - 2.7 8.4 18.7 0.96 9.8 10.8 1.9 1 1 1 2 2 2 0 Hepatocellular carcinoma-associated antigen 59 Pex16 PF08610.5 CDI80823.1 - 3.3 6.5 8.7 4.2 6.2 6.0 1.2 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) Paf1 PF03985.8 CDI80823.1 - 3.5 6.2 13.3 4.6 5.8 9.2 1.1 1 0 0 1 1 1 0 Paf1 DivIC PF04977.10 CDI80823.1 - 3.8 7.0 14.9 7.6 6.0 10.4 1.4 1 0 0 1 1 1 0 Septum formation initiator FAM176 PF14851.1 CDI80823.1 - 5.7 6.5 9.6 8.7 6.0 6.6 1.3 1 0 0 1 1 1 0 FAM176 family Anoctamin PF04547.7 CDI80823.1 - 5.9 5.4 7.5 7.6 5.0 5.2 1.1 1 0 0 1 1 1 0 Calcium-activated chloride channel Miff PF05644.6 CDI80823.1 - 7 6.1 12.5 9.2 5.8 8.6 1.3 1 0 0 1 1 1 0 Mitochondrial and peroxisomal fission factor Mff Peptidase_S64 PF08192.6 CDI80823.1 - 7.7 4.7 18.9 9.4 4.4 13.1 1.1 1 0 0 1 1 1 0 Peptidase family S64 DNA_pol_viral_N PF00242.12 CDI80823.1 - 9.4 5.1 18.3 12 4.8 12.7 1.1 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain Ndc1_Nup PF09531.5 CDI80823.1 - 9.5 4.5 13.1 10 4.3 9.1 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF2146 PF10220.4 CDI80823.1 - 9.7 4.0 12.6 12 3.7 8.7 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2146) Choline_transpo PF04515.7 CDI80825.1 - 0.28 9.8 0.0 0.28 9.8 0.0 2.0 2 1 0 2 2 2 0 Plasma-membrane choline transporter DUF1510 PF07423.6 CDI80825.1 - 6 6.1 42.1 2.9 7.1 8.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1510) N6_N4_Mtase PF01555.13 CDI80830.1 - 0.00056 19.4 4.1 0.32 10.4 2.8 3.2 1 1 0 1 1 1 1 DNA methylase Conotoxin PF02950.12 CDI80830.1 - 0.022 15.5 1.7 0.022 15.5 1.2 5.8 4 2 1 5 5 5 0 Conotoxin ODV-E18 PF10717.4 CDI80830.1 - 0.058 12.8 0.1 0.26 10.7 0.0 2.2 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 SR-25 PF10500.4 CDI80837.1 - 1.7e-05 24.4 17.6 1.7e-05 24.4 12.2 3.1 2 1 1 3 3 3 2 Nuclear RNA-splicing-associated protein Zip PF02535.17 CDI80837.1 - 0.006 15.6 7.2 0.006 15.6 5.0 3.0 2 1 1 3 3 3 1 ZIP Zinc transporter CAF-1_p150 PF11600.3 CDI80837.1 - 0.022 14.1 46.3 0.2 11.0 13.5 2.4 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Cwf_Cwc_15 PF04889.7 CDI80837.1 - 0.037 13.7 29.9 0.21 11.2 10.0 2.1 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein FA_desaturase PF00487.19 CDI80837.1 - 0.048 13.1 3.3 0.067 12.6 2.3 1.3 1 1 0 1 1 1 0 Fatty acid desaturase CDC45 PF02724.9 CDI80837.1 - 0.15 10.0 26.2 0.0075 14.3 3.0 2.1 2 0 0 2 2 2 0 CDC45-like protein DUF605 PF04652.11 CDI80837.1 - 1.2 8.4 48.6 1.7 7.9 10.2 2.1 2 0 0 2 2 2 0 Vta1 like Macoilin PF09726.4 CDI80837.1 - 4 5.5 51.0 1.1 7.5 12.8 2.2 2 0 0 2 2 2 0 Transmembrane protein RR_TM4-6 PF06459.7 CDI80837.1 - 4.2 7.1 28.7 1.2 9.0 5.0 2.2 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 DDHD PF02862.12 CDI80837.1 - 7.1 6.3 41.4 5.2 6.8 9.9 2.2 2 0 0 2 2 2 0 DDHD domain SAPS PF04499.10 CDI80838.1 - 0.1 11.1 21.3 0.13 10.8 14.8 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Neur_chan_memb PF02932.11 CDI80838.1 - 0.22 11.3 18.2 0.16 11.7 6.7 2.0 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Spore_coat_CotO PF14153.1 CDI80838.1 - 0.23 10.8 39.8 0.2 11.0 16.1 2.1 2 0 0 2 2 2 0 Spore coat protein CotO DUF1764 PF08576.5 CDI80838.1 - 0.3 11.8 32.1 0.26 12.0 11.2 2.3 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF1764) PAT1 PF09770.4 CDI80838.1 - 0.44 8.7 62.8 0.38 8.9 27.0 2.0 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 Pex14_N PF04695.8 CDI80838.1 - 0.64 10.0 42.8 0.036 14.1 14.9 2.1 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF2052 PF09747.4 CDI80838.1 - 1.2 8.9 35.5 1.3 8.9 14.7 2.1 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) DUF2360 PF10152.4 CDI80838.1 - 1.4 9.1 24.7 3.7 7.8 10.8 2.1 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) DUF3408 PF11888.3 CDI80838.1 - 1.8 8.4 26.9 3.4 7.5 1.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3408) Vfa1 PF08432.5 CDI80838.1 - 2 8.4 28.4 0.19 11.7 10.2 2.1 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 RR_TM4-6 PF06459.7 CDI80838.1 - 3 7.6 31.1 4.4 7.1 13.2 2.1 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 TRAP_alpha PF03896.11 CDI80838.1 - 7.3 5.5 13.0 0.46 9.4 3.7 2.0 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit AIF_C PF14721.1 CDI80838.1 - 7.8 6.7 31.0 1.7 8.8 12.1 2.1 2 0 0 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term TCP PF03634.8 CDI80838.1 - 8.7 6.7 29.7 5 7.5 2.9 2.3 2 0 0 2 2 2 0 TCP family transcription factor YqfQ PF14181.1 CDI80838.1 - 9.4 6.2 35.5 3.5 7.6 2.9 2.1 2 0 0 2 2 2 0 YqfQ-like protein DUF702 PF05142.7 CDI80838.1 - 9.8 6.3 25.8 3.7 7.6 9.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF702) DUF755 PF05501.6 CDI80842.1 - 0.00044 20.3 19.7 0.00044 20.3 13.7 4.2 4 0 0 4 4 4 1 Domain of unknown function (DUF755) eIF-3_zeta PF05091.7 CDI80842.1 - 6.8 5.1 29.2 2.2 6.7 9.1 2.2 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Na_trans_assoc PF06512.8 CDI80842.1 - 8.9 6.2 21.9 1.8 8.4 6.8 2.3 2 0 0 2 2 2 0 Sodium ion transport-associated AAA_23 PF13476.1 CDI80857.1 - 5.5 7.2 30.2 1.2 9.4 8.3 2.6 2 0 0 2 2 2 0 AAA domain TatD_DNase PF01026.16 CDI80858.1 - 2.5e-41 141.6 0.0 3.4e-41 141.1 0.0 1.1 1 0 0 1 1 1 1 TatD related DNase CAF-1_p150 PF11600.3 CDI80858.1 - 0.083 12.2 5.8 0.15 11.4 4.0 1.3 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Corona_nucleoca PF00937.13 CDI80858.1 - 0.11 11.4 6.9 0.16 10.9 4.8 1.1 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein RAP1 PF07218.6 CDI80858.1 - 0.12 10.4 2.2 0.14 10.2 1.5 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DUF4228 PF14009.1 CDI80858.1 - 0.36 10.9 3.7 0.61 10.2 1.8 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4228) PAT1 PF09770.4 CDI80859.1 - 0.0026 16.0 101.4 0.0037 15.5 70.3 1.3 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 Shadoo PF14999.1 CDI80860.1 - 0.041 13.7 5.1 0.66 9.8 2.9 2.2 2 0 0 2 2 2 0 Shadow of prion protein, neuroprotective Ribosomal_60s PF00428.14 CDI80860.1 - 0.051 13.9 21.6 0.53 10.7 1.4 2.5 2 0 0 2 2 2 0 60s Acidic ribosomal protein Cellulose_synt PF03552.9 CDI80860.1 - 7.8 4.6 6.0 7.6 4.6 4.1 1.3 1 0 0 1 1 1 0 Cellulose synthase TPK_catalytic PF04263.11 CDI80872.1 - 0.015 14.9 0.6 0.033 13.7 0.1 2.0 1 1 1 2 2 2 0 Thiamin pyrophosphokinase, catalytic domain PAT1 PF09770.4 CDI80872.1 - 0.018 13.3 60.1 0.024 12.9 41.7 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 MIP-T3 PF10243.4 CDI80872.1 - 0.026 13.0 34.1 0.036 12.5 23.6 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Ycf1 PF05758.7 CDI80872.1 - 0.04 11.6 19.4 0.054 11.2 13.5 1.2 1 0 0 1 1 1 0 Ycf1 Neur_chan_memb PF02932.11 CDI80872.1 - 0.058 13.2 19.5 0.074 12.9 13.5 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region PLRV_ORF5 PF01690.12 CDI80872.1 - 0.084 12.0 21.2 0.098 11.7 14.7 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein SAPS PF04499.10 CDI80872.1 - 0.31 9.6 19.6 0.39 9.2 13.6 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF1510 PF07423.6 CDI80872.1 - 0.51 9.6 27.0 0.97 8.7 18.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Hid1 PF12722.2 CDI80872.1 - 0.62 7.6 28.8 0.74 7.4 20.0 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Mem_trans PF03547.13 CDI80872.1 - 0.76 8.0 9.6 1.2 7.3 6.7 1.4 1 0 0 1 1 1 0 Membrane transport protein Dicty_REP PF05086.7 CDI80872.1 - 1.1 6.9 14.5 1.3 6.6 10.0 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein GPCR_chapero_1 PF11904.3 CDI80872.1 - 1.4 8.0 21.7 2.1 7.4 15.0 1.3 1 0 0 1 1 1 0 GPCR-chaperone CDC45 PF02724.9 CDI80872.1 - 1.8 6.4 29.0 2.4 6.1 20.1 1.1 1 0 0 1 1 1 0 CDC45-like protein Ndc1_Nup PF09531.5 CDI80872.1 - 2.1 6.6 21.6 2.5 6.3 15.0 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup GAGA_bind PF06217.7 CDI80872.1 - 3.9 7.3 29.6 5.3 6.9 20.6 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family Herpes_DNAp_acc PF04929.7 CDI80872.1 - 5.7 5.7 22.5 8.2 5.2 15.6 1.3 1 0 0 1 1 1 0 Herpes DNA replication accessory factor DUF4045 PF13254.1 CDI80872.1 - 7.7 5.6 26.0 13 4.9 18.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) FLO_LFY PF01698.11 CDI80872.1 - 8.1 5.1 27.6 14 4.4 19.1 1.3 1 0 0 1 1 1 0 Floricaula / Leafy protein RAB3GAP2_N PF14655.1 CDI80902.1 - 0.037 13.0 0.4 0.037 13.0 0.3 7.3 3 1 3 7 7 7 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Topo_C_assoc PF14370.1 CDI80902.1 - 0.5 10.0 0.1 0.5 10.0 0.0 5.9 5 1 0 5 5 5 0 C-terminal topoisomerase domain Ocnus PF05005.10 CDI80903.1 - 0.0017 18.1 0.0 0.003 17.4 0.0 1.3 1 0 0 1 1 1 1 Janus/Ocnus family (Ocnus) E1_dh PF00676.15 CDI80905.1 - 9.6e-62 208.3 0.0 1.1e-61 208.1 0.0 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component Transketolase_N PF00456.16 CDI80905.1 - 0.00022 20.1 0.0 0.00025 19.9 0.0 1.2 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain TPP_enzyme_C PF02775.16 CDI80905.1 - 0.00094 18.7 0.3 0.0073 15.8 0.1 2.2 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DXP_synthase_N PF13292.1 CDI80905.1 - 0.0036 16.2 0.0 0.0053 15.7 0.0 1.4 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase DNA_Packaging PF11053.3 CDI80905.1 - 0.023 14.3 0.0 0.54 9.8 0.0 2.2 2 0 0 2 2 2 0 Terminase DNA packaging enzyme Sda PF08970.5 CDI80905.1 - 0.18 11.3 0.2 0.43 10.1 0.2 1.6 1 0 0 1 1 1 0 Sporulation inhibitor A DUF755 PF05501.6 CDI80906.1 - 0.011 15.7 8.7 0.011 15.7 6.0 3.1 2 1 0 2 2 1 0 Domain of unknown function (DUF755) Herpes_UL87 PF03043.9 CDI80906.1 - 0.053 11.9 9.7 0.06 11.7 6.8 1.1 1 0 0 1 1 1 0 Herpesvirus UL87 family DUF1510 PF07423.6 CDI80906.1 - 0.065 12.6 21.6 0.086 12.2 10.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) Pox_Ag35 PF03286.9 CDI80906.1 - 0.076 12.5 12.6 0.037 13.5 5.9 2.0 2 0 0 2 2 2 0 Pox virus Ag35 surface protein SpoIIIAH PF12685.2 CDI80906.1 - 0.14 11.6 23.7 0.45 9.9 7.9 2.2 2 0 0 2 2 2 0 SpoIIIAH-like protein DUF913 PF06025.7 CDI80906.1 - 0.21 10.2 10.8 0.023 13.4 3.5 1.9 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) Neur_chan_memb PF02932.11 CDI80906.1 - 0.5 10.2 18.7 1.1 9.1 13.0 1.5 1 1 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region LMBR1 PF04791.11 CDI80906.1 - 0.74 8.3 8.8 1 7.8 5.9 1.4 1 1 0 1 1 1 0 LMBR1-like membrane protein BORG_CEP PF14957.1 CDI80906.1 - 0.75 10.7 21.3 0.68 10.8 0.9 2.3 2 0 0 2 2 2 0 Cdc42 effector Peptidase_S49_N PF08496.5 CDI80906.1 - 0.98 9.1 19.7 4.3 7.1 10.8 2.3 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Raftlin PF15250.1 CDI80906.1 - 1.6 7.1 21.8 3.3 6.1 12.1 2.0 2 0 0 2 2 2 0 Raftlin Peptidase_C6 PF00851.13 CDI80906.1 - 2.1 6.8 20.0 4 5.9 11.6 2.0 2 0 0 2 2 2 0 Helper component proteinase DUF1387 PF07139.6 CDI80906.1 - 2.8 7.4 20.2 3.9 7.0 0.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1387) RNA_pol_Rpb1_5 PF04998.12 CDI80906.1 - 2.8 7.1 13.8 3.4 6.8 7.9 1.9 2 0 0 2 2 2 0 RNA polymerase Rpb1, domain 5 AUX_IAA PF02309.11 CDI80906.1 - 3.7 7.2 21.9 6.3 6.4 10.7 2.1 2 0 0 2 2 2 0 AUX/IAA family DUF4045 PF13254.1 CDI80906.1 - 3.9 6.6 22.4 2.1 7.5 10.6 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4045) Serinc PF03348.10 CDI80906.1 - 4.3 5.9 21.4 7.5 5.1 0.3 2.3 2 0 0 2 2 2 0 Serine incorporator (Serinc) FAM163 PF15069.1 CDI80906.1 - 4.9 7.7 7.8 1.8 9.0 2.9 2.0 2 0 0 2 2 2 0 FAM163 family RCR PF12273.3 CDI80906.1 - 5.6 7.5 29.5 17 5.9 15.9 2.3 2 0 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red Band_3_cyto PF07565.8 CDI80906.1 - 5.6 6.3 27.6 8.5 5.8 0.7 2.2 2 0 0 2 2 2 0 Band 3 cytoplasmic domain DUF4613 PF15390.1 CDI80906.1 - 5.8 4.9 24.6 7.8 4.5 13.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4613) PPP4R2 PF09184.6 CDI80906.1 - 8.9 5.7 20.8 10 5.5 0.0 2.1 2 0 0 2 2 2 0 PPP4R2 Prok-JAB PF14464.1 CDI80908.1 - 0.00096 18.6 0.3 0.00096 18.6 0.2 3.7 3 2 0 3 3 3 1 Prokaryotic homologs of the JAB domain DUF3357 PF11837.3 CDI80908.1 - 0.051 13.4 0.5 0.051 13.4 0.4 4.8 2 2 2 5 5 5 0 Domain of unknown function (DUF3357) CD20 PF04103.10 CDI80908.1 - 0.1 12.5 11.1 0.5 10.2 0.6 3.2 2 1 1 3 3 3 0 CD20-like family DUF4064 PF13273.1 CDI80908.1 - 0.11 12.6 0.1 0.11 12.6 0.1 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF4064) DUF2615 PF11027.3 CDI80908.1 - 0.25 11.2 9.9 1.2 9.1 4.2 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF2615) SID-1_RNA_chan PF13965.1 CDI80908.1 - 1.7 6.7 7.9 2.8 6.0 5.5 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 PIG-P PF08510.7 CDI80908.1 - 2.7 7.6 6.5 70 3.0 2.6 3.0 2 1 0 2 2 2 0 PIG-P Serinc PF03348.10 CDI80908.1 - 8.5 4.9 26.3 1.2 7.7 3.2 2.9 2 1 1 3 3 3 0 Serine incorporator (Serinc) Methyltransf_26 PF13659.1 CDI80919.1 - 0.0012 18.8 6.1 0.0041 17.1 0.4 2.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 CDI80919.1 - 0.0058 17.1 0.1 0.0058 17.1 0.1 3.0 3 0 0 3 3 3 1 Methyltransferase domain MTS PF05175.9 CDI80919.1 - 0.0062 15.9 0.6 0.017 14.5 0.4 1.8 1 0 0 1 1 1 1 Methyltransferase small domain AAA_23 PF13476.1 CDI80919.1 - 0.037 14.3 0.2 0.037 14.3 0.2 3.0 2 1 0 2 2 2 0 AAA domain Methyltransf_11 PF08241.7 CDI80919.1 - 0.56 10.7 5.3 6.2 7.3 0.0 3.9 4 0 0 4 4 4 0 Methyltransferase domain PIG-P PF08510.7 CDI80919.1 - 0.82 9.3 4.2 8.7 5.9 0.1 2.6 2 0 0 2 2 2 0 PIG-P Spt20 PF12090.3 CDI80919.1 - 1.2 8.4 22.6 0.044 13.1 1.5 3.2 3 0 0 3 3 3 0 Spt20 family Methyltransf_12 PF08242.7 CDI80919.1 - 1.4 9.4 10.2 1.1 9.7 0.1 3.8 3 1 0 3 3 3 0 Methyltransferase domain PBP1_TM PF14812.1 CDI80919.1 - 1.9 8.8 12.3 19 5.6 0.4 3.4 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Methyltransf_23 PF13489.1 CDI80919.1 - 2.1 8.0 0.0 2.1 8.0 0.0 3.2 2 1 0 3 3 3 0 Methyltransferase domain RAP1 PF07218.6 CDI80933.1 - 0.069 11.2 1.8 0.081 11.0 1.2 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Ribosomal_60s PF00428.14 CDI80933.1 - 0.21 12.0 5.6 0.16 12.4 1.2 2.2 2 0 0 2 2 2 0 60s Acidic ribosomal protein PAT1 PF09770.4 CDI80934.1 - 0.0091 14.2 37.0 0.0084 14.4 25.6 1.1 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 Med15 PF09606.5 CDI80934.1 - 0.03 12.5 56.1 0.034 12.3 38.9 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Cons_hypoth698 PF03601.9 CDI80934.1 - 0.032 12.9 11.1 0.055 12.1 7.7 1.5 1 1 0 1 1 1 0 Conserved hypothetical protein 698 DUF819 PF05684.7 CDI80934.1 - 0.048 12.4 4.5 0.06 12.1 3.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF819) Serinc PF03348.10 CDI80934.1 - 0.075 11.7 13.5 0.077 11.6 9.4 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) AAA_23 PF13476.1 CDI80934.1 - 0.075 13.3 19.3 0.08 13.2 13.4 1.2 1 0 0 1 1 1 0 AAA domain TMEM51 PF15345.1 CDI80934.1 - 0.095 12.3 15.7 0.14 11.8 10.9 1.4 1 0 0 1 1 1 0 Transmembrane protein 51 SMN PF06003.7 CDI80934.1 - 0.13 11.3 2.6 0.16 11.0 1.8 1.1 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) Raftlin PF15250.1 CDI80934.1 - 0.14 10.6 13.9 0.14 10.6 9.6 1.0 1 0 0 1 1 1 0 Raftlin DDHD PF02862.12 CDI80934.1 - 0.14 11.8 14.2 0.14 11.8 9.8 1.2 1 0 0 1 1 1 0 DDHD domain eIF-3_zeta PF05091.7 CDI80934.1 - 0.15 10.6 21.0 0.14 10.7 14.6 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) YfhO PF09586.5 CDI80934.1 - 0.16 9.9 8.9 0.15 10.0 6.1 1.1 1 0 0 1 1 1 0 Bacterial membrane protein YfhO DUF2828 PF11443.3 CDI80934.1 - 0.2 9.8 11.4 0.19 9.8 7.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) FHIPEP PF00771.15 CDI80934.1 - 0.26 9.5 13.2 0.32 9.2 9.1 1.1 1 0 0 1 1 1 0 FHIPEP family DUF4395 PF14340.1 CDI80934.1 - 0.32 11.0 8.3 0.058 13.4 3.0 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4395) FLO_LFY PF01698.11 CDI80934.1 - 0.33 9.7 20.9 0.34 9.7 14.5 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein FPN1 PF06963.7 CDI80934.1 - 0.33 9.2 6.1 0.44 8.8 4.2 1.2 1 0 0 1 1 1 0 Ferroportin1 (FPN1) Folate_carrier PF01770.13 CDI80934.1 - 0.34 9.3 9.7 0.37 9.2 6.7 1.2 1 0 0 1 1 1 0 Reduced folate carrier DUF3260 PF11658.3 CDI80934.1 - 0.35 8.9 15.2 0.37 8.8 10.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3260) Bac_luciferase PF00296.15 CDI80934.1 - 0.46 9.5 11.8 0.61 9.1 8.2 1.1 1 0 0 1 1 1 0 Luciferase-like monooxygenase SID-1_RNA_chan PF13965.1 CDI80934.1 - 0.47 8.5 7.3 0.52 8.4 5.1 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 AUX_IAA PF02309.11 CDI80934.1 - 0.58 9.8 13.6 0.6 9.8 9.4 1.2 1 0 0 1 1 1 0 AUX/IAA family Pap_E4 PF02711.9 CDI80934.1 - 0.59 10.9 16.1 0.83 10.5 11.1 1.2 1 0 0 1 1 1 0 E4 protein Peptidase_S15 PF02129.13 CDI80934.1 - 0.69 9.2 16.6 0.76 9.1 11.5 1.2 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Peptidase_S49_N PF08496.5 CDI80934.1 - 0.7 9.6 16.4 0.93 9.2 11.4 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal TFIIA PF03153.8 CDI80934.1 - 0.83 9.4 34.4 1 9.1 23.8 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit MRP-S31 PF15433.1 CDI80934.1 - 0.83 9.0 22.9 0.91 8.8 15.9 1.1 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 Herpes_DNAp_acc PF04929.7 CDI80934.1 - 0.97 8.3 12.5 1.1 8.1 8.7 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Peroxin-13_N PF04088.8 CDI80934.1 - 1 9.2 9.2 1.5 8.7 6.4 1.4 1 0 0 1 1 1 0 Peroxin 13, N-terminal region DUF2232 PF09991.4 CDI80934.1 - 1.5 7.7 10.7 2 7.3 7.4 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) AMP-binding PF00501.23 CDI80934.1 - 1.5 7.0 5.8 1.6 7.0 4.1 1.1 1 0 0 1 1 1 0 AMP-binding enzyme Band_3_cyto PF07565.8 CDI80934.1 - 1.6 8.2 18.8 1.8 8.0 13.1 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain FAM60A PF15396.1 CDI80934.1 - 1.7 8.3 12.2 1.8 8.2 8.5 1.2 1 0 0 1 1 1 0 Protein Family FAM60A DUF342 PF03961.8 CDI80934.1 - 2 6.7 11.3 1.9 6.7 7.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Activator_LAG-3 PF11498.3 CDI80934.1 - 2.1 7.0 60.7 2.5 6.7 42.1 1.3 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Cellulose_synt PF03552.9 CDI80934.1 - 2.1 6.5 6.0 2 6.5 4.2 1.2 1 0 0 1 1 1 0 Cellulose synthase Nucleoside_tran PF01733.13 CDI80934.1 - 2.6 7.1 5.7 2.9 6.9 3.9 1.1 1 0 0 1 1 1 0 Nucleoside transporter SHR3_chaperone PF08229.6 CDI80934.1 - 2.8 6.8 23.0 4.3 6.2 15.9 1.3 1 0 0 1 1 1 0 ER membrane protein SH3 Baculo_PP31 PF05311.6 CDI80934.1 - 2.9 7.0 18.3 3.3 6.9 12.7 1.2 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) DUF913 PF06025.7 CDI80934.1 - 3 6.5 11.4 3.6 6.2 7.9 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DUF897 PF05982.7 CDI80934.1 - 4 6.1 10.3 5.6 5.6 7.2 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF897) DUF4446 PF14584.1 CDI80934.1 - 4.3 7.1 10.7 5.3 6.8 7.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) DUF2215 PF10225.4 CDI80934.1 - 4.6 6.6 9.9 5.1 6.4 6.8 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) Ycf1 PF05758.7 CDI80934.1 - 5 4.7 16.9 5.1 4.6 11.7 1.1 1 0 0 1 1 1 0 Ycf1 APG6 PF04111.7 CDI80934.1 - 5 6.0 23.9 4.9 6.0 16.6 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 YABBY PF04690.8 CDI80934.1 - 5.5 7.2 12.1 6.4 6.9 8.4 1.2 1 0 0 1 1 1 0 YABBY protein Neur_chan_memb PF02932.11 CDI80934.1 - 5.5 6.7 12.9 6.5 6.5 8.9 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Pex16 PF08610.5 CDI80934.1 - 5.7 5.8 20.3 6.8 5.5 14.1 1.1 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) OATP PF03137.15 CDI80934.1 - 6.7 4.6 15.4 7.1 4.5 10.2 1.4 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family RNA_pol_Rpb1_5 PF04998.12 CDI80934.1 - 7.4 5.7 12.3 8.9 5.4 8.5 1.1 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 Presenilin PF01080.12 CDI80934.1 - 9.8 4.8 13.4 11 4.7 9.3 1.1 1 0 0 1 1 1 0 Presenilin Peptidase_U57 PF05582.7 CDI80934.1 - 9.8 5.0 15.6 11 4.9 10.8 1.1 1 0 0 1 1 1 0 YabG peptidase U57 DUF1510 PF07423.6 CDI80944.1 - 0.002 17.5 26.3 0.0024 17.3 18.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) Pox_Ag35 PF03286.9 CDI80944.1 - 0.018 14.5 16.3 0.022 14.2 11.3 1.0 1 0 0 1 1 1 0 Pox virus Ag35 surface protein SAPS PF04499.10 CDI80944.1 - 0.059 12.0 18.6 0.052 12.1 12.9 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein FYDLN_acid PF09538.5 CDI80944.1 - 0.077 13.5 12.3 0.13 12.8 8.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) Ycf1 PF05758.7 CDI80944.1 - 0.094 10.4 24.6 0.1 10.3 17.0 1.0 1 0 0 1 1 1 0 Ycf1 PPP4R2 PF09184.6 CDI80944.1 - 0.13 11.7 20.5 0.16 11.4 14.2 1.2 1 0 0 1 1 1 0 PPP4R2 Peptidase_U57 PF05582.7 CDI80944.1 - 0.18 10.7 16.9 0.21 10.5 11.7 1.1 1 0 0 1 1 1 0 YabG peptidase U57 Dicty_REP PF05086.7 CDI80944.1 - 0.27 8.9 20.1 0.3 8.7 13.9 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Rtf2 PF04641.7 CDI80944.1 - 0.31 10.2 25.3 0.34 10.0 17.5 1.0 1 0 0 1 1 1 0 Rtf2 RING-finger YABBY PF04690.8 CDI80944.1 - 0.32 11.2 14.2 0.39 10.9 9.8 1.2 1 0 0 1 1 1 0 YABBY protein DDHD PF02862.12 CDI80944.1 - 0.4 10.4 24.2 0.44 10.3 16.8 1.1 1 0 0 1 1 1 0 DDHD domain Zip PF02535.17 CDI80944.1 - 0.44 9.5 9.5 0.44 9.5 6.6 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter AAA_11 PF13086.1 CDI80944.1 - 0.51 9.8 22.3 0.54 9.7 15.5 1.1 1 0 0 1 1 1 0 AAA domain DUF913 PF06025.7 CDI80944.1 - 0.51 9.0 15.2 0.57 8.8 10.5 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) POR_N PF01855.14 CDI80944.1 - 0.51 9.7 5.6 0.61 9.5 3.9 1.0 1 0 0 1 1 1 0 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg Gag_spuma PF03276.9 CDI80944.1 - 0.63 8.3 41.1 0.78 7.9 28.5 1.1 1 0 0 1 1 1 0 Spumavirus gag protein Plasmodium_Vir PF05795.6 CDI80944.1 - 0.66 9.1 10.8 0.75 8.9 7.5 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Baculo_PP31 PF05311.6 CDI80944.1 - 0.73 9.0 22.6 0.83 8.8 15.6 1.1 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) GAGA_bind PF06217.7 CDI80944.1 - 0.79 9.6 22.0 0.81 9.5 15.2 1.0 1 0 0 1 1 1 0 GAGA binding protein-like family OHA PF14418.1 CDI80944.1 - 0.82 9.2 0.0 0.82 9.2 0.0 3.0 1 1 1 2 2 1 0 OST-HTH Associated domain DUF2347 PF09804.4 CDI80944.1 - 0.92 8.7 14.1 0.96 8.6 9.8 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2347) Herpes_DNAp_acc PF04929.7 CDI80944.1 - 0.92 8.3 20.7 0.96 8.3 14.3 1.0 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Neur_chan_memb PF02932.11 CDI80944.1 - 0.96 9.2 16.8 1 9.1 11.6 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF822 PF05687.8 CDI80944.1 - 1 9.7 14.5 1.2 9.5 10.0 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF822) Gastrin PF00918.12 CDI80944.1 - 1 10.1 26.9 1.2 9.9 18.6 1.1 1 0 0 1 1 1 0 Gastrin/cholecystokinin family Gti1_Pac2 PF09729.4 CDI80944.1 - 1.3 8.8 21.2 1.7 8.5 14.7 1.1 1 0 0 1 1 1 0 Gti1/Pac2 family TT_ORF1 PF02956.9 CDI80944.1 - 1.4 7.3 19.0 1.4 7.2 13.1 1.0 1 0 0 1 1 1 0 TT viral orf 1 Hid1 PF12722.2 CDI80944.1 - 1.7 6.2 27.4 1.7 6.2 19.0 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SID-1_RNA_chan PF13965.1 CDI80944.1 - 1.8 6.6 16.3 2 6.4 11.3 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DUF2201_N PF13203.1 CDI80944.1 - 2 7.5 25.4 2.1 7.4 17.6 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain HCO3_cotransp PF00955.16 CDI80944.1 - 2.4 6.7 9.0 2.4 6.7 6.2 1.0 1 0 0 1 1 1 0 HCO3- transporter family NARP1 PF12569.3 CDI80944.1 - 2.4 6.8 26.2 2.7 6.6 18.2 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 PA26 PF04636.8 CDI80944.1 - 2.9 6.4 16.2 3 6.4 11.2 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) FAM91_C PF14648.1 CDI80944.1 - 3.4 6.3 12.6 3.6 6.3 8.7 1.1 1 0 0 1 1 1 0 FAM91 C-terminus DUF3260 PF11658.3 CDI80944.1 - 3.5 5.6 20.6 4.3 5.3 14.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3260) Peptidase_S64 PF08192.6 CDI80944.1 - 3.6 5.8 17.6 3.5 5.8 12.2 1.1 1 0 0 1 1 1 0 Peptidase family S64 Presenilin PF01080.12 CDI80944.1 - 4.3 6.0 19.4 5.1 5.8 13.4 1.1 1 0 0 1 1 1 0 Presenilin FLO_LFY PF01698.11 CDI80944.1 - 4.6 5.9 27.2 5.5 5.7 18.8 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein MMR1 PF08505.5 CDI80944.1 - 4.8 7.1 32.3 5 7.0 22.4 1.0 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein Med19 PF10278.4 CDI80944.1 - 4.9 6.7 17.1 6.1 6.4 11.8 1.1 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 NPR3 PF03666.8 CDI80944.1 - 5 5.5 25.1 5.5 5.4 17.4 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Peptidase_S49_N PF08496.5 CDI80944.1 - 5.1 6.8 26.8 8.4 6.1 18.5 1.4 1 1 0 1 1 1 0 Peptidase family S49 N-terminal Pal1 PF08316.6 CDI80944.1 - 5.8 7.3 16.6 8.3 6.8 11.5 1.2 1 0 0 1 1 1 0 Pal1 cell morphology protein RR_TM4-6 PF06459.7 CDI80944.1 - 5.8 6.7 27.4 6.4 6.5 19.0 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF2561 PF10812.3 CDI80944.1 - 5.9 6.4 6.9 7.8 6.0 4.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2561) Peptidase_S15 PF02129.13 CDI80944.1 - 6.5 6.0 19.7 8.7 5.6 13.7 1.1 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) CKAP2_C PF15297.1 CDI80944.1 - 6.6 5.4 29.1 7.1 5.3 20.1 1.1 1 0 0 1 1 1 0 Cytoskeleton-associated protein 2 C-terminus Cellulose_synt PF03552.9 CDI80944.1 - 6.7 4.8 13.9 7.7 4.6 9.6 1.1 1 0 0 1 1 1 0 Cellulose synthase RNA_pol_Rpb1_5 PF04998.12 CDI80944.1 - 7.6 5.7 16.8 8.1 5.6 11.6 1.1 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 FliP PF00813.15 CDI80944.1 - 7.7 6.1 14.2 10 5.7 9.9 1.2 1 0 0 1 1 1 0 FliP family Herpes_UL87 PF03043.9 CDI80944.1 - 8 4.7 14.2 8.4 4.6 9.9 1.1 1 0 0 1 1 1 0 Herpesvirus UL87 family Raftlin PF15250.1 CDI80944.1 - 8.5 4.7 26.7 9.5 4.6 18.5 1.0 1 0 0 1 1 1 0 Raftlin DUF3987 PF13148.1 CDI80944.1 - 9.5 4.6 18.3 9.7 4.6 12.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) CAF-1_p150 PF11600.3 CDI80945.1 - 0.33 10.3 40.3 0.39 10.0 27.9 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal PAT1 PF09770.4 CDI80945.1 - 1.2 7.2 83.5 1.4 7.0 57.9 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Herpes_env PF01673.13 CDI80945.1 - 1.3 7.4 16.5 1.8 7.0 11.4 1.3 1 0 0 1 1 1 0 Herpesvirus putative major envelope glycoprotein Ndc1_Nup PF09531.5 CDI80945.1 - 2 6.7 33.6 2.7 6.3 23.3 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Ycf1 PF05758.7 CDI80945.1 - 2 6.0 29.0 2.6 5.6 20.1 1.2 1 0 0 1 1 1 0 Ycf1 CAP_N PF01213.14 CDI80945.1 - 2.1 7.5 15.1 2.9 7.0 10.4 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal FAM60A PF15396.1 CDI80945.1 - 2.6 7.7 25.8 3.4 7.3 17.9 1.2 1 0 0 1 1 1 0 Protein Family FAM60A Utp14 PF04615.8 CDI80945.1 - 2.7 6.0 39.2 3.3 5.7 27.2 1.0 1 0 0 1 1 1 0 Utp14 protein Hid1 PF12722.2 CDI80945.1 - 3.9 5.0 35.8 4.5 4.8 24.8 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein CDC45 PF02724.9 CDI80945.1 - 6.4 4.6 31.9 7.8 4.4 22.1 1.1 1 0 0 1 1 1 0 CDC45-like protein Exonuc_VII_L PF02601.10 CDI80945.1 - 6.7 5.8 28.4 7.9 5.5 19.7 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF2360 PF10152.4 CDI80948.1 - 4 7.7 5.2 32 4.8 1.2 2.7 2 2 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) Robl_LC7 PF03259.12 CDI80949.1 - 8e-08 31.7 0.0 1.1e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 Roadblock/LC7 domain Arm PF00514.18 CDI80950.1 - 1.1e-15 56.8 8.8 0.0066 16.2 0.1 8.0 7 1 1 8 8 8 5 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 CDI80950.1 - 1.1e-08 35.2 18.5 0.001 19.2 1.9 4.9 2 2 2 4 4 4 3 HEAT repeats HEAT PF02985.17 CDI80950.1 - 6.9e-06 25.7 5.7 6.2 7.1 0.0 6.6 6 0 0 6 6 6 2 HEAT repeat Adaptin_N PF01602.15 CDI80950.1 - 0.0003 19.2 0.4 1.7 6.9 0.0 3.6 3 2 0 3 3 3 2 Adaptin N terminal region HEAT_EZ PF13513.1 CDI80950.1 - 0.0085 16.5 23.1 0.026 14.9 0.1 6.0 3 2 2 5 5 5 3 HEAT-like repeat Proteasom_PSMB PF10508.4 CDI80950.1 - 0.027 12.7 0.1 0.58 8.3 0.0 2.7 3 0 0 3 3 3 0 Proteasome non-ATPase 26S subunit ADIP PF11559.3 CDI80952.1 - 0.026 14.4 0.9 0.04 13.8 0.6 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding MIP-T3 PF10243.4 CDI80952.1 - 0.044 12.2 0.5 0.06 11.8 0.3 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 SlyX PF04102.7 CDI80952.1 - 0.057 13.7 1.6 0.092 13.1 0.2 1.9 1 1 1 2 2 2 0 SlyX Reo_sigmaC PF04582.7 CDI80952.1 - 0.1 11.7 0.4 0.15 11.1 0.3 1.4 1 0 0 1 1 1 0 Reovirus sigma C capsid protein F-box PF00646.28 CDI80955.1 - 0.0008 19.0 0.3 0.003 17.1 0.2 2.0 1 0 0 1 1 1 1 F-box domain TSP_1 PF00090.14 CDI80958.1 - 1e-05 25.5 10.8 0.0013 18.7 0.5 2.8 3 0 0 3 3 3 2 Thrombospondin type 1 domain CTDII PF01556.13 CDI80961.1 - 2.6e-23 81.7 0.1 6.1e-14 51.6 0.0 2.3 2 0 0 2 2 2 2 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 CDI80961.1 - 8.2e-07 28.9 14.0 1.9e-06 27.8 9.7 1.7 1 0 0 1 1 1 1 DnaJ central domain RIX1 PF08167.7 CDI80961.1 - 0.074 12.7 0.0 1.2 8.7 0.0 2.1 2 0 0 2 2 2 0 rRNA processing/ribosome biogenesis A_deaminase PF00962.17 CDI80962.1 - 2.1e-50 171.5 0.0 8.4e-50 169.5 0.0 1.9 1 1 0 1 1 1 1 Adenosine/AMP deaminase Med15 PF09606.5 CDI80967.1 - 0.00018 19.8 28.9 0.0002 19.7 20.0 1.2 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal Dehydrin PF00257.14 CDI80967.1 - 0.015 15.6 8.1 16 5.8 5.7 2.7 1 1 0 1 1 1 0 Dehydrin IncA PF04156.9 CDI80967.1 - 0.019 14.5 12.2 0.019 14.5 8.5 2.0 2 1 1 3 3 3 0 IncA protein VIT1 PF01988.14 CDI80967.1 - 0.099 12.1 9.7 0.048 13.1 4.0 1.9 2 0 0 2 2 2 0 VIT family PAT1 PF09770.4 CDI80967.1 - 0.32 9.1 28.8 0.38 8.9 20.0 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SOBP PF15279.1 CDI80967.1 - 0.4 11.0 14.7 0.61 10.4 10.2 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein RAP1 PF07218.6 CDI80967.1 - 0.61 8.1 6.4 0.91 7.5 4.5 1.3 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) RNA_pol_Rpc4 PF05132.9 CDI80967.1 - 0.67 9.9 11.5 0.3 11.0 3.5 2.2 2 0 0 2 2 2 0 RNA polymerase III RPC4 CAF-1_p150 PF11600.3 CDI80967.1 - 0.78 9.0 23.7 1.5 8.1 6.5 2.1 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal BSP_II PF05432.6 CDI80967.1 - 0.88 8.7 7.3 1.8 7.8 0.1 2.0 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) EphA2_TM PF14575.1 CDI80967.1 - 1 9.7 4.5 4.9 7.6 1.7 2.5 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Tetraspannin PF00335.15 CDI80967.1 - 3.2 6.9 4.8 1.2 8.3 1.5 1.6 2 0 0 2 2 2 0 Tetraspanin family SR-25 PF10500.4 CDI80967.1 - 3.6 6.9 36.1 0.5 9.7 4.7 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Pap_E4 PF02711.9 CDI80967.1 - 4.2 8.2 15.7 13 6.6 5.3 2.4 2 0 0 2 2 2 0 E4 protein TCP PF03634.8 CDI80967.1 - 5 7.5 22.9 3.6 7.9 1.3 2.3 2 0 0 2 2 2 0 TCP family transcription factor TraG-D_C PF12696.2 CDI80967.1 - 5.1 6.9 13.5 3 7.7 1.6 2.2 2 0 0 2 2 2 0 TraM recognition site of TraD and TraG FimP PF09766.4 CDI80967.1 - 5.4 5.9 22.1 0.18 10.8 10.9 1.6 2 0 0 2 2 2 0 Fms-interacting protein MDFI PF15316.1 CDI80967.1 - 8.6 6.3 18.6 17 5.3 8.2 2.1 2 0 0 2 2 2 0 MyoD family inhibitor DUF3449 PF11931.3 CDI80967.1 - 9.5 5.6 12.8 3.2 7.2 4.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3449) DUF2413 PF10310.4 CDI80972.1 - 7.6 5.2 82.2 0.19 10.5 9.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2413) DUF1510 PF07423.6 CDI80975.1 - 0.001 18.5 22.9 0.001 18.5 15.8 2.3 1 1 1 2 2 2 1 Protein of unknown function (DUF1510) Peptidase_S49_N PF08496.5 CDI80975.1 - 0.0022 17.7 16.0 0.0022 17.7 11.1 3.5 1 1 1 2 2 2 1 Peptidase family S49 N-terminal PRA1 PF03208.14 CDI80975.1 - 3.8 6.8 8.1 8.2 5.7 5.4 1.8 1 1 0 1 1 1 0 PRA1 family protein Fork_head_N PF08430.7 CDI80980.1 - 0.052 13.9 3.3 0.064 13.6 2.3 1.1 1 0 0 1 1 1 0 Forkhead N-terminal region TFIIA PF03153.8 CDI80980.1 - 0.11 12.3 15.1 0.1 12.4 10.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CDK2AP PF09806.4 CDI80980.1 - 0.32 11.1 13.8 0.38 10.9 9.5 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein DOR PF14839.1 CDI80980.1 - 0.39 10.4 13.5 0.46 10.1 9.4 1.2 1 0 0 1 1 1 0 DOR family PepSY_2 PF13670.1 CDI80980.1 - 1.3 8.9 12.7 2 8.3 8.8 1.3 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain CcmD PF04995.9 CDI80980.1 - 1.7 8.4 6.3 2.7 7.7 4.4 1.4 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) Med3 PF11593.3 CDI80980.1 - 2.5 7.2 16.2 3.7 6.6 11.2 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Cgr1 PF03879.9 CDI80984.1 - 0.0091 16.1 17.5 0.0091 16.1 12.2 2.2 2 0 0 2 2 2 1 Cgr1 family SprA-related PF12118.3 CDI80984.1 - 1.5 8.1 81.5 0.12 11.6 33.2 2.1 2 0 0 2 2 2 0 SprA-related family TFIIA PF03153.8 CDI80984.1 - 3.5 7.4 65.3 4.8 6.9 45.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Peptidase_S64 PF08192.6 CDI80984.1 - 5.7 5.1 34.5 8 4.6 23.9 1.2 1 0 0 1 1 1 0 Peptidase family S64 CAF-1_p150 PF11600.3 CDI80984.1 - 7.3 5.9 42.8 0.9 8.8 18.5 2.1 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal ERCC4 PF02732.10 CDI81008.1 - 1e-15 57.7 0.0 1e-15 57.7 0.0 3.6 3 1 0 3 3 3 2 ERCC4 domain SAPS PF04499.10 CDI81008.1 - 0.00015 20.5 4.3 0.0031 16.2 2.3 2.2 2 0 0 2 2 2 2 SIT4 phosphatase-associated protein GAGA_bind PF06217.7 CDI81012.1 - 1.7 8.5 12.6 0.65 9.9 0.6 2.1 2 0 0 2 2 2 0 GAGA binding protein-like family PsbQ PF05757.6 CDI81012.1 - 2.8 7.3 20.7 0.41 10.0 6.5 2.4 1 1 1 2 2 2 0 Oxygen evolving enhancer protein 3 (PsbQ) Pox_Ag35 PF03286.9 CDI81016.1 - 4.6e-05 23.0 16.2 4.6e-05 23.0 11.3 3.0 3 0 0 3 3 3 1 Pox virus Ag35 surface protein PAT1 PF09770.4 CDI81016.1 - 8.2e-05 21.0 61.0 8.2e-05 21.0 42.3 3.1 2 1 1 3 3 3 1 Topoisomerase II-associated protein PAT1 SprA-related PF12118.3 CDI81016.1 - 0.00018 20.9 46.7 0.00018 20.9 32.4 3.5 3 1 0 3 3 3 1 SprA-related family DUF4401 PF14351.1 CDI81016.1 - 0.36 9.7 7.0 0.46 9.4 3.9 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4401) DUF4045 PF13254.1 CDI81016.1 - 0.49 9.6 38.6 0.069 12.4 15.3 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4045) CAF-1_p150 PF11600.3 CDI81021.1 - 1.2e-05 24.7 42.8 1.6e-05 24.4 29.7 1.1 1 0 0 1 1 1 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal Med15 PF09606.5 CDI81021.1 - 0.001 17.4 91.7 0.0011 17.3 63.6 1.0 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal SOBP PF15279.1 CDI81021.1 - 0.029 14.7 30.4 0.035 14.4 21.1 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein CDC45 PF02724.9 CDI81021.1 - 0.054 11.5 35.4 0.071 11.1 24.5 1.1 1 0 0 1 1 1 0 CDC45-like protein Utp14 PF04615.8 CDI81021.1 - 0.076 11.1 41.1 0.089 10.9 28.5 1.1 1 0 0 1 1 1 0 Utp14 protein DUF4045 PF13254.1 CDI81021.1 - 0.077 12.2 30.1 0.099 11.9 20.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) PAT1 PF09770.4 CDI81021.1 - 0.096 10.9 77.3 0.11 10.6 53.6 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 GAGA_bind PF06217.7 CDI81021.1 - 0.14 12.0 34.8 0.17 11.8 24.1 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family TFIIA PF03153.8 CDI81021.1 - 0.15 11.9 60.2 0.19 11.5 41.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CENP-T PF15511.1 CDI81021.1 - 0.3 10.2 32.3 0.37 9.9 22.4 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Hid1 PF12722.2 CDI81021.1 - 0.42 8.2 38.1 0.53 7.9 26.4 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein TATR PF03430.8 CDI81021.1 - 0.58 8.7 30.5 0.75 8.3 21.2 1.1 1 0 0 1 1 1 0 Trans-activating transcriptional regulator Atg14 PF10186.4 CDI81021.1 - 0.94 8.3 37.4 1.1 8.1 25.9 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Ycf1 PF05758.7 CDI81021.1 - 1 7.0 35.0 1.2 6.7 24.2 1.1 1 0 0 1 1 1 0 Ycf1 Nha1_C PF08619.5 CDI81021.1 - 1.1 8.4 37.3 1.6 7.9 25.8 1.1 1 0 0 1 1 1 0 Alkali metal cation/H+ antiporter Nha1 C terminus PLRV_ORF5 PF01690.12 CDI81021.1 - 1.6 7.8 34.0 2 7.5 23.5 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein DUF853 PF05872.7 CDI81021.1 - 1.8 6.8 32.7 3.1 6.0 22.6 1.5 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF853) Caldesmon PF02029.10 CDI81021.1 - 1.8 6.8 39.6 2.3 6.5 27.4 1.0 1 0 0 1 1 1 0 Caldesmon DUF2201_N PF13203.1 CDI81021.1 - 2 7.5 37.8 2.6 7.1 26.2 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain Asp-B-Hydro_N PF05279.6 CDI81021.1 - 2.3 7.9 33.6 3 7.6 23.3 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region AvrE PF11725.3 CDI81021.1 - 4 4.3 38.5 4.6 4.1 26.7 1.0 1 0 0 1 1 1 0 Pathogenicity factor Daxx PF03344.10 CDI81021.1 - 6.8 5.0 39.9 8.2 4.7 27.7 1.1 1 0 0 1 1 1 0 Daxx Family Parvo_coat PF00740.13 CDI81021.1 - 7.2 5.4 41.2 8.6 5.1 28.6 1.1 1 0 0 1 1 1 0 Parvovirus coat protein VP2 Mitofilin PF09731.4 CDI81021.1 - 9.2 4.7 42.0 11 4.5 29.1 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Utp14 PF04615.8 CDI81037.1 - 8.1 4.4 126.4 11 4.0 87.6 1.1 1 0 0 1 1 1 0 Utp14 protein FAM176 PF14851.1 CDI81038.1 - 0.18 11.4 4.4 1 9.0 1.3 2.4 2 0 0 2 2 2 0 FAM176 family Anoctamin PF04547.7 CDI81038.1 - 0.28 9.8 2.8 0.14 10.7 0.3 1.6 2 0 0 2 2 2 0 Calcium-activated chloride channel Pex16 PF08610.5 CDI81038.1 - 1.1 8.1 8.8 1.3 7.9 3.5 2.1 2 0 0 2 2 2 0 Peroxisomal membrane protein (Pex16) Utp14 PF04615.8 CDI81039.1 - 0.29 9.2 43.3 0.36 8.9 30.0 1.0 1 0 0 1 1 1 0 Utp14 protein Baculo_PP31 PF05311.6 CDI81045.1 - 0.0024 17.1 1.0 0.0033 16.7 0.7 1.1 1 0 0 1 1 1 1 Baculovirus 33KDa late protein (PP31) TMEM51 PF15345.1 CDI81045.1 - 0.0069 16.1 4.4 0.01 15.5 3.0 1.2 1 0 0 1 1 1 1 Transmembrane protein 51 Beta-lactamase PF00144.19 CDI81045.1 - 0.022 13.7 0.1 0.036 13.0 0.1 1.3 1 0 0 1 1 1 0 Beta-lactamase Dehydrin PF00257.14 CDI81045.1 - 2 8.7 10.5 3 8.1 4.4 2.3 2 0 0 2 2 2 0 Dehydrin Agouti PF05039.7 CDI81045.1 - 6.2 7.2 6.6 9.7 6.6 4.2 1.7 1 1 0 1 1 1 0 Agouti protein FHIPEP PF00771.15 CDI81047.1 - 0.00015 20.2 17.7 0.0044 15.4 8.7 2.1 2 0 0 2 2 2 2 FHIPEP family Med15 PF09606.5 CDI81047.1 - 0.00077 17.7 71.4 0.011 13.9 41.1 2.1 2 0 0 2 2 2 2 ARC105 or Med15 subunit of Mediator complex non-fungal WD40 PF00400.27 CDI81047.1 - 0.0087 15.9 0.1 0.19 11.6 0.0 2.7 2 1 0 2 2 2 1 WD domain, G-beta repeat SR-25 PF10500.4 CDI81047.1 - 0.011 15.1 13.0 0.011 15.1 9.0 3.6 3 1 1 4 4 2 0 Nuclear RNA-splicing-associated protein V_ATPase_I PF01496.14 CDI81047.1 - 0.019 12.8 15.6 0.027 12.3 10.8 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Zip PF02535.17 CDI81047.1 - 0.061 12.3 4.0 0.22 10.5 0.8 2.2 2 0 0 2 2 2 0 ZIP Zinc transporter Nha1_C PF08619.5 CDI81047.1 - 0.21 10.8 27.2 0.2 10.8 11.4 2.1 2 0 0 2 2 2 0 Alkali metal cation/H+ antiporter Nha1 C terminus N6_N4_Mtase PF01555.13 CDI81047.1 - 0.29 10.5 3.2 0.81 9.1 2.3 1.6 1 1 0 1 1 1 0 DNA methylase Herpes_UL87 PF03043.9 CDI81047.1 - 0.48 8.7 17.3 1.2 7.3 7.0 2.1 2 0 0 2 2 2 0 Herpesvirus UL87 family FAM60A PF15396.1 CDI81047.1 - 1.8 8.2 29.2 4.4 6.9 14.0 2.3 2 0 0 2 2 2 0 Protein Family FAM60A Rtf2 PF04641.7 CDI81047.1 - 1.9 7.6 32.0 2.4 7.2 1.5 2.2 2 0 0 2 2 2 0 Rtf2 RING-finger PA26 PF04636.8 CDI81047.1 - 2.2 6.8 15.3 0.18 10.4 7.2 1.6 2 0 0 2 2 2 0 PA26 p53-induced protein (sestrin) SOBP PF15279.1 CDI81047.1 - 3.9 7.7 32.3 4.7 7.4 12.9 2.1 2 0 0 2 2 2 0 Sine oculis-binding protein Corona_nucleoca PF00937.13 CDI81047.1 - 4 6.2 45.2 0.14 11.0 7.6 2.4 2 0 0 2 2 2 0 Coronavirus nucleocapsid protein HCO3_cotransp PF00955.16 CDI81047.1 - 4.4 5.8 5.1 8 4.9 3.5 1.4 1 0 0 1 1 1 0 HCO3- transporter family DUF1510 PF07423.6 CDI81047.1 - 4.8 6.4 32.3 0.21 10.9 13.9 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1510) PAT1 PF09770.4 CDI81047.1 - 9.6 4.2 64.4 2.5 6.2 2.7 2.2 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 K_channel_TID PF07941.6 CDI81050.1 - 0.0059 16.8 6.3 0.0059 16.8 4.4 2.5 3 0 0 3 3 3 1 Potassium channel Kv1.4 tandem inactivation domain Vfa1 PF08432.5 CDI81068.1 - 0.046 13.7 22.0 0.056 13.4 15.2 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 YqfQ PF14181.1 CDI81068.1 - 0.14 12.2 27.0 0.16 12.0 18.7 1.0 1 0 0 1 1 1 0 YqfQ-like protein DUF1510 PF07423.6 CDI81068.1 - 0.17 11.1 27.6 0.19 11.0 19.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DUF2072 PF09845.4 CDI81068.1 - 0.31 10.9 14.1 0.39 10.6 9.8 1.1 1 0 0 1 1 1 0 Zn-ribbon containing protein (DUF2072) Drc1-Sld2 PF11719.3 CDI81068.1 - 0.37 9.8 23.5 0.44 9.5 16.3 1.0 1 0 0 1 1 1 0 DNA replication and checkpoint protein DUF3449 PF11931.3 CDI81068.1 - 0.72 9.3 23.1 0.78 9.2 16.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3449) DUF3807 PF12720.2 CDI81068.1 - 0.74 9.9 26.4 0.82 9.8 18.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) DDHD PF02862.12 CDI81068.1 - 0.86 9.3 20.7 1 9.1 14.3 1.2 1 0 0 1 1 1 0 DDHD domain Caldesmon PF02029.10 CDI81068.1 - 1.3 7.3 26.6 1.5 7.1 18.5 1.0 1 0 0 1 1 1 0 Caldesmon TRAP_alpha PF03896.11 CDI81068.1 - 1.7 7.5 14.0 1.9 7.4 9.7 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Rtf2 PF04641.7 CDI81068.1 - 2.3 7.3 25.0 2.6 7.1 17.3 1.0 1 0 0 1 1 1 0 Rtf2 RING-finger CDC45 PF02724.9 CDI81068.1 - 2.8 5.8 24.1 2.8 5.8 16.7 1.0 1 0 0 1 1 1 0 CDC45-like protein DUF4446 PF14584.1 CDI81068.1 - 2.8 7.7 16.3 3.3 7.5 11.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) Pox_Ag35 PF03286.9 CDI81068.1 - 3 7.3 18.5 3.4 7.1 12.8 1.0 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Trypan_PARP PF05887.6 CDI81068.1 - 3.1 7.6 6.0 3.7 7.3 4.2 1.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) RR_TM4-6 PF06459.7 CDI81068.1 - 3.3 7.5 25.8 3.9 7.3 17.9 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 BORG_CEP PF14957.1 CDI81068.1 - 3.5 8.5 15.0 4.1 8.3 10.4 1.2 1 0 0 1 1 1 0 Cdc42 effector DUF4045 PF13254.1 CDI81068.1 - 3.5 6.8 21.6 3.6 6.7 15.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) FYDLN_acid PF09538.5 CDI81068.1 - 3.8 8.1 16.4 5.8 7.5 11.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) Abi_2 PF07751.6 CDI81068.1 - 4.7 7.3 7.8 5 7.2 5.4 1.0 1 0 0 1 1 1 0 Abi-like protein Zip PF02535.17 CDI81068.1 - 4.8 6.1 12.2 5 6.0 8.5 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter DUF913 PF06025.7 CDI81068.1 - 5 5.7 14.7 4.9 5.8 10.2 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Sec62 PF03839.11 CDI81068.1 - 5.2 6.4 20.2 5.6 6.3 14.0 1.0 1 0 0 1 1 1 0 Translocation protein Sec62 Spore_coat_CotO PF14153.1 CDI81068.1 - 6.1 6.2 37.9 6.6 6.1 26.2 1.0 1 0 0 1 1 1 0 Spore coat protein CotO Paf1 PF03985.8 CDI81068.1 - 6.1 5.4 34.1 6.9 5.2 23.6 1.0 1 0 0 1 1 1 0 Paf1 SelP_N PF04592.9 CDI81068.1 - 6.2 6.1 18.1 7.2 5.9 12.5 1.0 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Gag_spuma PF03276.9 CDI81068.1 - 6.4 4.9 39.5 7.8 4.6 27.4 1.0 1 0 0 1 1 1 0 Spumavirus gag protein Paramyxo_ncap PF00973.14 CDI81068.1 - 6.5 5.3 19.3 6.5 5.3 13.4 1.0 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Raftlin PF15250.1 CDI81068.1 - 6.5 5.1 22.0 7.4 4.9 15.3 1.0 1 0 0 1 1 1 0 Raftlin RRN3 PF05327.6 CDI81068.1 - 6.7 4.6 17.8 6.6 4.7 12.4 1.0 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Gti1_Pac2 PF09729.4 CDI81068.1 - 7.4 6.4 16.3 9 6.1 11.3 1.2 1 0 0 1 1 1 0 Gti1/Pac2 family NARP1 PF12569.3 CDI81068.1 - 7.4 5.1 23.8 8.2 5.0 16.5 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DDRGK PF09756.4 CDI81068.1 - 7.8 5.8 36.6 8.9 5.6 25.4 1.0 1 0 0 1 1 1 0 DDRGK domain DUF4637 PF15470.1 CDI81068.1 - 8 6.0 10.0 9.5 5.8 6.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) DUF3987 PF13148.1 CDI81068.1 - 8.5 4.8 22.7 9.4 4.6 15.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) Tim54 PF11711.3 CDI81068.1 - 8.5 4.8 21.4 10 4.5 14.9 1.0 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 SprA-related PF12118.3 CDI81068.1 - 8.7 5.5 51.7 10 5.3 35.8 1.1 1 0 0 1 1 1 0 SprA-related family TraV PF09676.5 CDI81068.1 - 9 7.0 17.0 16 6.2 11.8 1.3 1 0 0 1 1 1 0 Type IV conjugative transfer system lipoprotein (TraV) FAM60A PF15396.1 CDI81068.1 - 9 5.9 18.9 10 5.7 13.1 1.0 1 0 0 1 1 1 0 Protein Family FAM60A NPR3 PF03666.8 CDI81068.1 - 9.1 4.6 21.2 10 4.5 14.7 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 MRP-S31 PF15433.1 CDI81068.1 - 9.4 5.5 26.2 9.8 5.4 18.1 1.0 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 RP-C_C PF11800.3 CDI81068.1 - 9.5 5.8 22.6 9.8 5.8 15.6 1.0 1 0 0 1 1 1 0 Replication protein C C-terminal region CENP-T PF15511.1 CDI81068.1 - 9.8 5.2 24.3 11 5.1 16.9 1.0 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T K_channel_TID PF07941.6 CDI81070.1 - 0.077 13.2 17.4 0.042 14.0 6.0 3.0 3 0 0 3 3 3 0 Potassium channel Kv1.4 tandem inactivation domain Mgr1 PF08602.5 CDI81070.1 - 1.1 8.1 6.3 0.29 10.1 0.1 2.1 2 0 0 2 2 2 0 Mgr1-like, i-AAA protease complex subunit Med15 PF09606.5 CDI81070.1 - 9.6 4.2 91.1 0.082 11.1 17.0 2.3 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal SUV3_C PF12513.3 CDI81071.1 - 0.99 8.8 4.0 2.2 7.7 0.1 3.1 2 1 1 3 3 3 0 Mitochondrial degradasome RNA helicase subunit C terminal Prominin PF05478.6 CDI81071.1 - 4.3 4.7 7.5 5 4.5 5.2 1.3 1 0 0 1 1 1 0 Prominin WD40 PF00400.27 CDI81072.1 - 2.3e-13 49.4 4.9 3.7e-06 26.6 0.0 4.7 5 0 0 5 5 5 3 WD domain, G-beta repeat BBS2_Mid PF14783.1 CDI81072.1 - 0.033 13.9 0.0 8.8 6.1 0.0 2.4 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, middle region Med16 PF11635.3 CDI81072.1 - 0.15 9.9 0.0 0.64 7.9 0.0 1.8 2 1 0 2 2 2 0 Mediator complex subunit 16 DUF4557 PF15101.1 CDI81072.1 - 0.9 9.3 6.3 1.6 8.4 4.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) CDK5_activator PF03261.10 CDI81072.1 - 5.4 6.2 8.2 13 4.9 5.7 1.6 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein Suf PF05843.9 CDI81072.1 - 7.8 6.1 8.5 13 5.3 5.9 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) His_Phos_1 PF00300.17 CDI81079.1 - 1.2e-08 35.2 4.6 0.00032 20.8 0.0 2.2 1 1 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) Nitroreductase PF00881.19 CDI81079.1 - 0.00044 20.1 5.2 0.00048 19.9 3.6 1.1 1 0 0 1 1 1 1 Nitroreductase family Activator_LAG-3 PF11498.3 CDI81079.1 - 0.016 13.9 14.4 0.021 13.5 10.0 1.3 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Med15 PF09606.5 CDI81079.1 - 0.02 13.0 17.4 0.025 12.8 12.0 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF3371 PF11851.3 CDI81079.1 - 0.089 13.4 4.8 0.12 13.0 3.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3371) IER PF05760.7 CDI81079.1 - 0.09 12.6 6.8 0.092 12.6 4.7 1.1 1 0 0 1 1 1 0 Immediate early response protein (IER) PadR PF03551.9 CDI81079.1 - 0.13 12.0 0.9 0.28 10.9 0.0 1.9 2 0 0 2 2 2 0 Transcriptional regulator PadR-like family CDK2AP PF09806.4 CDI81079.1 - 0.32 11.1 12.1 0.44 10.7 8.4 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein Mcm10 PF09332.6 CDI81079.1 - 0.39 10.0 3.8 0.44 9.8 2.6 1.1 1 0 0 1 1 1 0 Mcm10 replication factor PAT1 PF09770.4 CDI81079.1 - 0.4 8.8 12.4 0.42 8.7 8.6 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF4557 PF15101.1 CDI81079.1 - 0.63 9.8 5.5 0.78 9.5 3.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) DUF4139 PF13598.1 CDI81079.1 - 1.5 8.0 8.7 1.8 7.8 6.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4139) UPF0560 PF10577.4 CDI81079.1 - 6.4 4.8 8.5 7.7 4.6 5.9 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 TFIIA PF03153.8 CDI81079.1 - 8.2 6.2 12.2 10 5.8 8.5 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Zip PF02535.17 CDI81080.1 - 0.093 11.7 12.9 0.0098 14.9 1.9 2.3 2 0 0 2 2 2 0 ZIP Zinc transporter RuBisCO_large_N PF02788.11 CDI81080.1 - 0.64 9.7 0.0 0.64 9.7 0.0 2.5 3 0 0 3 3 3 0 Ribulose bisphosphate carboxylase large chain, N-terminal domain AAA_23 PF13476.1 CDI81080.1 - 2.8 8.1 48.0 0.24 11.6 9.0 2.2 2 0 0 2 2 2 0 AAA domain Peptidase_S49_N PF08496.5 CDI81085.1 - 0.2 11.4 2.2 0.7 9.6 1.5 1.9 1 0 0 1 1 1 0 Peptidase family S49 N-terminal TFIIA PF03153.8 CDI81085.1 - 5.6 6.7 48.4 2.3 8.0 21.3 3.3 3 0 0 3 3 3 0 Transcription factor IIA, alpha/beta subunit CTP_transf_2 PF01467.21 CDI81089.1 - 0.0038 17.2 2.5 0.0038 17.2 1.8 3.5 1 1 1 2 2 2 1 Cytidylyltransferase Alpha-amylase PF00128.19 CDI81090.1 - 0.21 10.9 7.4 0.25 10.7 5.1 1.0 1 0 0 1 1 1 0 Alpha amylase, catalytic domain DDHD PF02862.12 CDI81090.1 - 5 6.8 20.1 6.3 6.5 13.9 1.2 1 0 0 1 1 1 0 DDHD domain DUF2361 PF10153.4 CDI81090.1 - 7.9 6.7 23.5 10 6.3 16.3 1.2 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2361) DUF3439 PF11921.3 CDI81091.1 - 0.003 17.2 7.6 0.0044 16.7 5.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3439) SSP160 PF06933.6 CDI81091.1 - 0.007 14.4 16.1 0.0081 14.2 11.2 1.0 1 0 0 1 1 1 1 Special lobe-specific silk protein SSP160 Sporozoite_P67 PF05642.6 CDI81091.1 - 0.0099 13.8 4.2 0.011 13.6 2.9 1.2 1 0 0 1 1 1 1 Sporozoite P67 surface antigen PsaN PF05479.6 CDI81091.1 - 0.015 15.2 1.9 0.017 15.0 1.3 1.2 1 0 0 1 1 1 0 Photosystem I reaction centre subunit N (PSAN or PSI-N) Rubella_E2 PF05749.6 CDI81091.1 - 0.032 13.4 1.7 0.039 13.2 1.2 1.2 1 0 0 1 1 1 0 Rubella membrane glycoprotein E2 PGA2 PF07543.7 CDI81091.1 - 0.042 13.6 5.7 0.055 13.2 3.9 1.1 1 0 0 1 1 1 0 Protein trafficking PGA2 SpoIIIAH PF12685.2 CDI81091.1 - 0.27 10.7 17.3 0.32 10.4 12.0 1.0 1 0 0 1 1 1 0 SpoIIIAH-like protein MSP1_C PF07462.6 CDI81091.1 - 0.37 9.1 12.4 0.42 8.9 8.6 1.1 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus VIT1 PF01988.14 CDI81091.1 - 0.98 8.8 10.3 0.035 13.6 1.6 1.9 1 1 1 2 2 2 0 VIT family FAM60A PF15396.1 CDI81091.1 - 0.99 9.1 9.9 1.2 8.8 6.8 1.1 1 0 0 1 1 1 0 Protein Family FAM60A CD20 PF04103.10 CDI81091.1 - 3.4 7.5 5.7 1.6 8.6 0.3 2.0 1 1 1 2 2 2 0 CD20-like family DUF2681 PF10883.3 CDI81091.1 - 5.2 7.3 22.4 3.5 7.8 6.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) Utp14 PF04615.8 CDI81091.1 - 7.8 4.5 17.8 9.3 4.2 12.3 1.0 1 0 0 1 1 1 0 Utp14 protein Dicty_REP PF05086.7 CDI81091.1 - 9 3.9 20.4 13 3.4 14.1 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein AF-4 PF05110.8 CDI81094.1 - 1.1e-05 23.5 39.6 1.4e-05 23.2 27.4 1.0 1 0 0 1 1 1 1 AF-4 proto-oncoprotein TraU PF06834.6 CDI81094.1 - 0.23 10.5 7.3 0.24 10.4 1.8 2.4 1 1 1 2 2 2 0 TraU protein DUF4629 PF15442.1 CDI81094.1 - 0.38 10.8 31.5 0.14 12.2 7.5 3.5 3 1 0 3 3 3 0 Domain of unknown function (DUF4629) FimP PF09766.4 CDI81094.1 - 1.5 7.7 21.2 0.52 9.3 9.0 2.5 3 0 0 3 3 3 0 Fms-interacting protein DUF3141 PF11339.3 CDI81094.1 - 2 6.6 8.7 3.5 5.8 6.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3141) Spt5_N PF11942.3 CDI81094.1 - 2.9 8.5 15.3 2.4 8.8 2.7 3.3 3 0 0 3 3 3 0 Spt5 transcription elongation factor, acidic N-terminal SR-25 PF10500.4 CDI81094.1 - 4.4 6.7 53.4 1.3 8.4 8.4 3.1 2 1 1 3 3 3 0 Nuclear RNA-splicing-associated protein BAF1_ABF1 PF04684.8 CDI81094.1 - 4.7 5.9 18.9 0.22 10.3 9.3 1.7 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor Patched PF02460.13 CDI81095.1 - 7.3e-98 328.4 6.8 1.1e-80 271.7 0.0 3.0 2 1 0 2 2 2 2 Patched family Sterol-sensing PF12349.3 CDI81095.1 - 3.9e-32 110.8 8.3 3.9e-32 110.8 5.8 2.7 3 0 0 3 3 3 1 Sterol-sensing domain of SREBP cleavage-activation VIT1 PF01988.14 CDI81095.1 - 0.041 13.3 0.2 0.041 13.3 0.1 4.9 6 0 0 6 6 6 0 VIT family IZUMO PF15005.1 CDI81095.1 - 0.4 10.6 1.8 0.35 10.9 0.1 1.7 2 0 0 2 2 2 0 Izumo sperm-egg fusion ACR_tran PF00873.14 CDI81095.1 - 1.5 6.0 9.7 2.3 5.4 6.7 1.2 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family MORN PF02493.15 CDI81096.1 - 1.2e-31 106.5 41.8 2.3e-06 26.9 1.0 8.0 8 0 0 8 8 8 7 MORN repeat CRAL_TRIO_2 PF13716.1 CDI81097.1 - 0.00013 21.8 0.1 0.0002 21.2 0.1 1.2 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO PF00650.15 CDI81097.1 - 0.0012 18.3 0.1 0.0028 17.1 0.1 1.6 1 1 0 1 1 1 1 CRAL/TRIO domain Ribosomal_60s PF00428.14 CDI81097.1 - 0.0022 18.3 5.9 0.0022 18.3 4.1 1.8 2 0 0 2 2 2 1 60s Acidic ribosomal protein DUF4286 PF14114.1 CDI81100.1 - 0.1 12.8 0.1 0.16 12.2 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4286) Pox_Ag35 PF03286.9 CDI81103.1 - 0.047 13.2 12.1 0.052 13.0 8.4 1.0 1 0 0 1 1 1 0 Pox virus Ag35 surface protein AUX_IAA PF02309.11 CDI81103.1 - 0.1 12.3 14.9 0.12 12.1 10.3 1.0 1 0 0 1 1 1 0 AUX/IAA family Rtf2 PF04641.7 CDI81103.1 - 0.15 11.2 23.0 0.19 10.9 15.9 1.0 1 0 0 1 1 1 0 Rtf2 RING-finger F-protein PF00469.15 CDI81103.1 - 0.24 10.7 19.9 0.28 10.5 13.8 1.0 1 0 0 1 1 1 0 Negative factor, (F-Protein) or Nef Na_trans_assoc PF06512.8 CDI81103.1 - 0.74 9.7 15.8 0.91 9.4 10.9 1.1 1 0 0 1 1 1 0 Sodium ion transport-associated Auxin_canalis PF05703.6 CDI81103.1 - 0.88 9.3 11.2 1.1 8.9 7.8 1.1 1 0 0 1 1 1 0 Auxin canalisation SGT1 PF07093.6 CDI81103.1 - 1.7 6.9 22.5 2.1 6.5 15.6 1.1 1 0 0 1 1 1 0 SGT1 protein PFEMP PF03011.10 CDI81103.1 - 1.8 8.8 22.8 2 8.7 15.8 1.0 1 0 0 1 1 1 0 PFEMP DBL domain CDC45 PF02724.9 CDI81103.1 - 2.1 6.2 18.4 2.3 6.1 12.8 1.0 1 0 0 1 1 1 0 CDC45-like protein Apt1 PF10351.4 CDI81103.1 - 2.3 6.9 16.1 2.6 6.7 11.1 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain Glyco_transf_15 PF01793.11 CDI81103.1 - 2.8 6.8 15.7 3.9 6.3 10.9 1.3 1 0 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase Hid1 PF12722.2 CDI81103.1 - 2.9 5.4 22.4 3.3 5.2 15.5 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Pan_kinase PF03309.9 CDI81103.1 - 3 7.3 11.9 3.6 7.0 8.3 1.1 1 0 0 1 1 1 0 Type III pantothenate kinase DUF1510 PF07423.6 CDI81103.1 - 3.3 7.0 22.4 4 6.7 15.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) FAM60A PF15396.1 CDI81103.1 - 4.7 6.8 18.8 5.5 6.6 13.0 1.0 1 0 0 1 1 1 0 Protein Family FAM60A DUF2201_N PF13203.1 CDI81103.1 - 4.7 6.2 25.9 5.6 6.0 18.0 1.0 1 0 0 1 1 1 0 Putative metallopeptidase domain DUF966 PF06136.8 CDI81103.1 - 6.1 6.1 20.8 7.1 5.9 14.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF966) hDGE_amylase PF14701.1 CDI81103.1 - 6.1 5.6 16.4 6.2 5.5 11.4 1.0 1 0 0 1 1 1 0 glucanotransferase domain of human glycogen debranching enzyme Glyco_hydro_3_C PF01915.17 CDI81103.1 - 7.3 6.0 8.9 8.8 5.7 6.1 1.0 1 0 0 1 1 1 0 Glycosyl hydrolase family 3 C-terminal domain PGP_phosphatase PF09419.5 CDI81103.1 - 7.3 5.9 7.1 13 5.0 4.9 1.6 1 1 0 1 1 1 0 Mitochondrial PGP phosphatase Lin-8 PF03353.10 CDI81103.1 - 7.7 5.7 30.3 8.8 5.5 21.0 1.0 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Med15 PF09606.5 CDI81107.1 - 0.00075 17.8 88.8 0.00083 17.6 27.6 2.1 2 0 0 2 2 2 2 ARC105 or Med15 subunit of Mediator complex non-fungal PT PF04886.7 CDI81113.1 - 0.0026 17.0 11.2 0.012 14.9 0.5 3.3 1 1 1 2 2 2 2 PT repeat Suf PF05843.9 CDI81116.1 - 0.08 12.6 3.5 0.13 12.0 2.4 1.4 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF912 PF06024.7 CDI81116.1 - 0.1 12.6 0.0 0.24 11.4 0.0 1.6 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) UNC45-central PF11701.3 CDI81116.1 - 0.13 11.9 1.2 0.23 11.1 0.8 1.4 1 0 0 1 1 1 0 Myosin-binding striated muscle assembly central ABC2_membrane_2 PF12679.2 CDI81116.1 - 0.18 10.6 0.3 0.26 10.1 0.2 1.3 1 0 0 1 1 1 0 ABC-2 family transporter protein EIIBC-GUT_N PF03612.9 CDI81116.1 - 0.18 11.3 1.3 0.36 10.4 0.9 1.4 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus DUF4557 PF15101.1 CDI81116.1 - 1.1 9.0 9.2 2 8.2 6.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) AAA_23 PF13476.1 CDI81116.1 - 1.6 9.0 6.0 2 8.6 4.1 1.1 1 0 0 1 1 1 0 AAA domain Pex14_N PF04695.8 CDI81116.1 - 3.3 7.7 14.3 0.059 13.4 3.6 2.3 2 1 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF4094 PF13334.1 CDI81116.1 - 7.6 7.0 9.3 17 5.8 6.3 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4094) Peptidase_C65 PF10275.4 CDI81118.1 - 1.9e-22 79.8 2.8 3.3e-22 79.0 2.0 1.4 1 1 0 1 1 1 1 Peptidase C65 Otubain Peptidase_M91 PF14891.1 CDI81118.1 - 0.0091 16.0 0.2 0.28 11.2 0.0 2.2 2 0 0 2 2 2 1 Effector protein Spt20 PF12090.3 CDI81118.1 - 0.02 14.2 1.2 0.024 14.0 0.8 1.4 1 0 0 1 1 1 0 Spt20 family Activator_LAG-3 PF11498.3 CDI81118.1 - 0.027 13.2 17.6 0.036 12.8 12.2 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Med15 PF09606.5 CDI81118.1 - 0.032 12.4 17.4 0.038 12.1 12.0 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal OTU PF02338.14 CDI81118.1 - 0.072 13.6 1.4 0.075 13.6 0.0 1.8 2 0 0 2 2 2 0 OTU-like cysteine protease DUF3336 PF11815.3 CDI81118.1 - 0.1 12.1 1.9 0.43 10.0 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3336) Suf PF05843.9 CDI81118.1 - 0.14 11.8 4.2 0.19 11.4 2.9 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) SR-25 PF10500.4 CDI81118.1 - 0.17 11.3 14.9 0.058 12.8 2.8 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Peptidase_M64 PF09471.5 CDI81118.1 - 0.27 10.8 3.9 0.05 13.2 0.4 1.5 2 0 0 2 2 2 0 IgA Peptidase M64 CDK2AP PF09806.4 CDI81118.1 - 0.31 11.2 10.2 2 8.6 2.7 2.2 2 0 0 2 2 2 0 Cyclin-dependent kinase 2-associated protein Ribosomal_60s PF00428.14 CDI81118.1 - 1.5 9.2 8.7 3.4 8.1 6.1 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein Flavodoxin_2 PF02525.12 CDI81118.1 - 2.4 7.5 6.4 6.4 6.2 2.3 2.1 2 0 0 2 2 2 0 Flavodoxin-like fold DUF935 PF06074.7 CDI81118.1 - 4.9 5.7 12.5 28 3.2 8.7 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF935) CAF-1_p150 PF11600.3 CDI81118.1 - 5.6 6.2 13.2 10 5.4 9.2 1.4 1 1 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal mTERF PF02536.9 CDI81119.1 - 1.3e-09 37.1 0.1 1e-07 30.9 0.0 2.2 2 0 0 2 2 2 2 mTERF DUF2098 PF09871.4 CDI81119.1 - 0.019 14.8 3.3 0.022 14.6 0.2 2.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2098) IF-2B PF01008.12 CDI81120.1 - 1.6e-09 37.1 0.4 7.6e-09 34.9 0.3 1.9 1 1 0 1 1 1 1 Initiation factor 2 subunit family Suf PF05843.9 CDI81120.1 - 0.0016 18.2 3.5 0.0016 18.2 2.4 3.0 2 1 0 3 3 2 1 Suppressor of forked protein (Suf) Band_3_cyto PF07565.8 CDI81120.1 - 0.0028 17.1 11.6 0.013 14.9 0.9 2.4 2 0 0 2 2 2 2 Band 3 cytoplasmic domain DUF4557 PF15101.1 CDI81120.1 - 0.0055 16.5 7.5 0.0055 16.5 5.2 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4557) Spt20 PF12090.3 CDI81120.1 - 0.012 15.0 0.6 0.012 15.0 0.4 2.7 2 1 0 2 2 1 0 Spt20 family Peptidase_S49_N PF08496.5 CDI81120.1 - 0.021 14.6 8.6 0.035 13.8 0.0 2.4 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Neur_chan_memb PF02932.11 CDI81120.1 - 0.15 11.9 10.2 1.6 8.5 0.3 2.5 2 1 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Apt1 PF10351.4 CDI81120.1 - 0.54 9.0 11.0 0.028 13.2 1.0 2.2 2 0 0 2 2 2 0 Golgi-body localisation protein domain CPSF100_C PF13299.1 CDI81120.1 - 0.54 10.4 10.4 0.56 10.3 0.5 2.6 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal TFIIA PF03153.8 CDI81120.1 - 0.66 9.8 44.2 1.3 8.8 17.1 2.3 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Phage_int_SAM_5 PF13102.1 CDI81120.1 - 0.7 9.8 11.9 0.48 10.4 0.5 2.3 2 0 0 2 2 2 0 Phage integrase SAM-like domain Spore_YhcN_YlaJ PF09580.5 CDI81120.1 - 0.94 9.5 13.9 0.36 10.9 0.7 2.4 2 0 0 2 2 2 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) RCR PF12273.3 CDI81120.1 - 1.1 9.7 30.1 0.19 12.3 9.7 2.8 2 0 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red eIF-3_zeta PF05091.7 CDI81120.1 - 1.2 7.6 19.5 0.22 10.0 3.2 2.1 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) FAM176 PF14851.1 CDI81120.1 - 1.4 8.6 6.9 1.3 8.7 0.2 2.6 2 0 0 2 2 2 0 FAM176 family zf-DHHC PF01529.15 CDI81120.1 - 2.2 7.6 11.8 1.4 8.3 0.1 2.2 2 0 0 2 2 2 0 DHHC palmitoyltransferase ARS2 PF04959.8 CDI81121.1 - 3.7e-05 24.0 0.1 5.8e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Arsenite-resistance protein 2 PocR PF10114.4 CDI81121.1 - 0.016 14.3 0.0 0.03 13.4 0.0 1.4 1 0 0 1 1 1 0 Sensory domain found in PocR AIP3 PF03915.8 CDI81121.1 - 0.02 13.8 3.1 0.028 13.3 2.1 1.2 1 0 0 1 1 1 0 Actin interacting protein 3 HNH PF01844.18 CDI81121.1 - 0.052 13.4 1.9 5.3 7.0 0.5 2.4 2 0 0 2 2 2 0 HNH endonuclease Cnd1_N PF12922.2 CDI81121.1 - 0.096 12.3 2.3 0.18 11.3 1.6 1.4 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1, N-term DUF506 PF04720.7 CDI81121.1 - 0.27 10.8 3.6 0.49 9.9 2.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF506) zf-C2H2 PF00096.21 CDI81121.1 - 1.2 9.5 5.9 3.1 8.3 4.1 1.7 1 0 0 1 1 1 0 Zinc finger, C2H2 type Pex14_N PF04695.8 CDI81121.1 - 2.1 8.4 9.8 7.4 6.6 6.8 2.0 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Rotamase_2 PF13145.1 CDI81121.1 - 2.2 8.9 7.3 15 6.2 0.0 3.2 3 0 0 3 3 3 0 PPIC-type PPIASE domain Tmemb_9 PF05434.6 CDI81121.1 - 2.7 7.7 5.7 7.4 6.3 4.0 1.7 1 0 0 1 1 1 0 TMEM9 DUF1777 PF08648.7 CDI81121.1 - 7 6.3 14.6 1.1 8.9 5.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1777) P12 PF12669.2 CDI81125.1 - 3 8.1 0.0 3 8.1 0.0 3.4 3 0 0 3 3 3 0 Virus attachment protein p12 family YceG PF02618.11 CDI81127.1 - 0.01 14.8 3.7 0.013 14.5 2.6 1.1 1 0 0 1 1 1 0 YceG-like family RIB43A PF05914.7 CDI81127.1 - 0.79 8.2 27.8 0.65 8.5 0.9 2.0 2 0 0 2 2 2 0 RIB43A CBP4 PF07960.6 CDI81127.1 - 0.81 9.3 18.2 0.55 9.8 7.1 2.4 2 0 0 2 2 2 0 CBP4 YfhO PF09586.5 CDI81127.1 - 0.87 7.5 8.4 0.99 7.3 5.8 1.0 1 0 0 1 1 1 0 Bacterial membrane protein YfhO CDK2AP PF09806.4 CDI81127.1 - 0.93 9.6 34.2 0.1 12.8 5.2 2.0 1 1 1 2 2 2 0 Cyclin-dependent kinase 2-associated protein SR-25 PF10500.4 CDI81127.1 - 1.2 8.5 19.1 0.85 9.0 4.8 2.1 1 1 1 2 2 2 0 Nuclear RNA-splicing-associated protein DUF4407 PF14362.1 CDI81127.1 - 1.4 7.7 15.1 2.2 7.1 10.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF755 PF05501.6 CDI81131.1 - 0.0078 16.2 25.6 0.0078 16.2 17.7 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF755) TFIIF_alpha PF05793.7 CDI81131.1 - 0.027 12.8 12.6 0.035 12.4 8.7 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Med15 PF09606.5 CDI81131.1 - 0.057 11.6 39.3 0.069 11.3 27.2 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal SAPS PF04499.10 CDI81131.1 - 0.12 11.0 6.9 0.12 10.9 4.8 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Hid1 PF12722.2 CDI81131.1 - 0.24 9.0 14.6 0.26 8.9 10.1 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF2217 PF10265.4 CDI81131.1 - 0.86 8.2 17.5 1.7 7.3 8.8 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2217) Cwf_Cwc_15 PF04889.7 CDI81131.1 - 2.4 7.8 19.3 0.71 9.5 11.2 1.6 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Plasmodium_Vir PF05795.6 CDI81131.1 - 4.7 6.3 9.9 6.8 5.7 6.9 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein FAM60A PF15396.1 CDI81131.1 - 5.5 6.6 13.8 2.3 7.8 6.9 1.9 2 0 0 2 2 2 0 Protein Family FAM60A DUF3807 PF12720.2 CDI81131.1 - 9.5 6.3 22.0 4.6 7.3 11.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3807) Macoilin PF09726.4 CDI81131.1 - 9.5 4.3 22.5 11 4.1 15.6 1.1 1 0 0 1 1 1 0 Transmembrane protein Shadoo PF14999.1 CDI81135.1 - 0.0012 18.6 2.4 0.0017 18.2 1.6 1.2 1 0 0 1 1 1 1 Shadow of prion protein, neuroprotective CAF-1_p150 PF11600.3 CDI81135.1 - 0.0067 15.8 31.3 0.0083 15.5 21.7 1.1 1 0 0 1 1 1 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal Utp14 PF04615.8 CDI81135.1 - 0.62 8.1 35.9 0.64 8.1 24.9 1.0 1 0 0 1 1 1 0 Utp14 protein DUF4045 PF13254.1 CDI81135.1 - 0.9 8.7 28.5 0.95 8.6 19.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) PAT1 PF09770.4 CDI81135.1 - 1.4 7.1 79.4 1.5 6.9 55.0 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Ycf1 PF05758.7 CDI81135.1 - 1.6 6.3 29.8 1.7 6.2 20.7 1.0 1 0 0 1 1 1 0 Ycf1 Med15 PF09606.5 CDI81135.1 - 1.6 6.8 103.6 1.9 6.5 71.8 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF1510 PF07423.6 CDI81135.1 - 2 7.7 33.4 2.5 7.4 23.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Asp-B-Hydro_N PF05279.6 CDI81135.1 - 2.5 7.8 26.0 2.8 7.7 18.0 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region DUF3450 PF11932.3 CDI81135.1 - 3 7.0 55.1 4.7 6.3 38.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) PMSI1 PF15322.1 CDI81135.1 - 3.2 6.7 23.7 5.2 6.0 16.5 1.3 1 0 0 1 1 1 0 Protein missing in infertile sperm 1, putative DUF342 PF03961.8 CDI81135.1 - 3.8 5.8 19.6 4 5.7 13.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Hid1 PF12722.2 CDI81135.1 - 3.9 5.0 33.3 4.1 4.9 23.1 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein GAGA_bind PF06217.7 CDI81135.1 - 4 7.3 32.3 4.6 7.1 22.4 1.0 1 0 0 1 1 1 0 GAGA binding protein-like family Caldesmon PF02029.10 CDI81135.1 - 6.1 5.1 29.3 7.3 4.8 20.3 1.1 1 0 0 1 1 1 0 Caldesmon BTV_NS2 PF04514.7 CDI81135.1 - 7.1 5.4 25.0 8.8 5.1 17.4 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Macoilin PF09726.4 CDI81135.1 - 7.5 4.7 26.1 9.5 4.3 18.1 1.2 1 0 0 1 1 1 0 Transmembrane protein PLRV_ORF5 PF01690.12 CDI81135.1 - 7.7 5.5 30.9 8.6 5.3 21.4 1.0 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein SAGA-Tad1 PF12767.2 CDI81135.1 - 9.8 5.7 40.7 11 5.6 28.2 1.1 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit Cwf_Cwc_15 PF04889.7 CDI81137.1 - 0.037 13.7 7.8 0.042 13.5 5.4 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Podoplanin PF05808.6 CDI81137.1 - 0.037 13.5 3.7 0.047 13.2 2.6 1.1 1 0 0 1 1 1 0 Podoplanin FAM60A PF15396.1 CDI81137.1 - 0.055 13.2 2.8 0.062 13.0 1.9 1.1 1 0 0 1 1 1 0 Protein Family FAM60A Pap_E4 PF02711.9 CDI81137.1 - 0.083 13.7 2.0 0.17 12.7 1.4 1.5 1 0 0 1 1 1 0 E4 protein DUF2217 PF10265.4 CDI81137.1 - 0.094 11.4 4.0 0.099 11.3 2.8 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) APC_CDC26 PF10471.4 CDI81137.1 - 0.097 13.4 12.2 0.19 12.5 8.4 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex APC subunit 1 PMSI1 PF15322.1 CDI81137.1 - 0.12 11.4 7.9 0.15 11.0 5.5 1.2 1 0 0 1 1 1 0 Protein missing in infertile sperm 1, putative MFMR PF07777.6 CDI81137.1 - 0.13 12.1 9.8 0.17 11.8 6.8 1.1 1 0 0 1 1 1 0 G-box binding protein MFMR Plasmodium_Vir PF05795.6 CDI81137.1 - 0.14 11.3 2.5 0.15 11.2 1.8 1.0 1 0 0 1 1 1 0 Plasmodium vivax Vir protein DUF1510 PF07423.6 CDI81137.1 - 0.19 11.0 6.9 0.22 10.8 4.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Hid1 PF12722.2 CDI81137.1 - 0.2 9.2 3.9 0.2 9.3 2.7 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Vfa1 PF08432.5 CDI81137.1 - 0.2 11.6 6.2 0.27 11.2 4.3 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Hex_IIIa PF02455.11 CDI81137.1 - 0.41 9.2 3.9 0.48 9.0 2.7 1.0 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) DUF3449 PF11931.3 CDI81137.1 - 0.43 10.0 3.8 0.52 9.8 2.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3449) Presenilin PF01080.12 CDI81137.1 - 0.5 9.1 2.6 0.56 8.9 1.8 1.2 1 0 0 1 1 1 0 Presenilin DUF1635 PF07795.6 CDI81137.1 - 0.61 9.4 7.9 0.8 9.0 5.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) RAP1 PF07218.6 CDI81137.1 - 0.63 8.0 9.8 0.62 8.0 6.8 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) CobT PF06213.7 CDI81137.1 - 0.74 8.8 10.9 0.81 8.7 7.6 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Macoilin PF09726.4 CDI81137.1 - 1.1 7.4 12.0 1.2 7.3 8.3 1.1 1 0 0 1 1 1 0 Transmembrane protein DUF2051 PF09738.4 CDI81137.1 - 1.3 8.2 10.9 1.7 7.8 7.6 1.1 1 0 0 1 1 1 0 Double stranded RNA binding protein (DUF2051) DNA_pol_viral_N PF00242.12 CDI81137.1 - 2 7.3 7.7 2.4 7.0 5.4 1.1 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain NPR3 PF03666.8 CDI81137.1 - 2.1 6.8 6.6 2.4 6.5 4.6 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 TFIIF_alpha PF05793.7 CDI81137.1 - 2.1 6.6 11.0 2.5 6.3 7.6 1.0 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF4636 PF15468.1 CDI81137.1 - 3.4 7.0 11.6 4.6 6.6 8.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4636) B12D PF06522.6 CDI81137.1 - 3.9 7.2 6.4 0.49 10.1 1.5 1.7 2 0 0 2 2 2 0 NADH-ubiquinone reductase complex 1 MLRQ subunit Apt1 PF10351.4 CDI81137.1 - 4.2 6.1 11.2 4.6 5.9 7.7 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF3827 PF12877.2 CDI81137.1 - 4.6 5.2 11.2 5.6 4.9 7.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) DUF2146 PF10220.4 CDI81137.1 - 4.7 5.0 8.9 5 4.9 6.2 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2146) CDC45 PF02724.9 CDI81137.1 - 7.4 4.4 11.7 9.1 4.1 8.1 1.1 1 0 0 1 1 1 0 CDC45-like protein RAB3GAP2_N PF14655.1 CDI81140.1 - 5.1 5.9 33.7 1.2 8.0 1.9 3.6 3 0 0 3 3 3 0 Rab3 GTPase-activating protein regulatory subunit N-terminus DUF4248 PF14053.1 CDI81148.1 - 0.068 12.7 1.8 7.2 6.2 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4248) VPR PF00522.13 CDI81148.1 - 0.21 11.4 1.3 0.51 10.1 0.1 2.2 2 0 0 2 2 2 0 VPR/VPX protein Corona_nucleoca PF00937.13 CDI81149.1 - 0.044 12.7 1.1 0.066 12.1 0.7 1.2 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein EDR1 PF14381.1 CDI81150.1 - 8.7e-19 67.9 0.0 1.9e-18 66.7 0.0 1.5 1 0 0 1 1 1 1 Ethylene-responsive protein kinase Le-CTR1 LRR_6 PF13516.1 CDI81150.1 - 1.7e-06 27.5 1.4 6 7.2 0.0 6.5 7 0 0 7 7 7 2 Leucine Rich repeat LRR_1 PF00560.28 CDI81150.1 - 0.0072 16.1 6.1 58 4.3 0.0 6.4 7 0 0 7 7 7 0 Leucine Rich Repeat LRR_7 PF13504.1 CDI81150.1 - 3.9 8.1 13.2 2.4e+02 2.6 0.0 7.0 8 0 0 8 8 8 0 Leucine rich repeat Ribosomal_60s PF00428.14 CDI81174.1 - 0.11 12.9 1.0 0.17 12.3 0.7 1.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein Suf PF05843.9 CDI81174.1 - 0.23 11.1 13.3 0.29 10.8 9.2 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF605 PF04652.11 CDI81174.1 - 0.35 10.2 26.3 0.4 10.0 18.2 1.0 1 0 0 1 1 1 0 Vta1 like Ebola_NP PF05505.7 CDI81174.1 - 2 6.3 14.9 2.3 6.2 10.3 1.0 1 0 0 1 1 1 0 Ebola nucleoprotein CAF-1_p150 PF11600.3 CDI81174.1 - 2.5 7.4 30.5 0.71 9.2 10.5 2.1 1 1 1 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF572 PF04502.8 CDI81174.1 - 4.1 6.5 13.4 5.3 6.1 9.3 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) GEMIN8 PF15348.1 CDI81184.1 - 0.0094 16.0 0.8 0.0094 16.0 0.6 3.5 2 1 1 3 3 2 1 Gemini of Cajal bodies-associated protein 8 RskA PF10099.4 CDI81184.1 - 0.013 15.2 0.2 0.013 15.2 0.1 4.0 2 1 1 3 3 2 0 Anti-sigma-K factor rskA Med15 PF09606.5 CDI81184.1 - 0.12 10.5 90.5 0.48 8.5 4.5 2.1 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF4199 PF13858.1 CDI81184.1 - 0.25 11.2 0.0 0.25 11.2 0.0 3.9 2 1 0 2 2 1 0 Protein of unknown function (DUF4199) P12 PF12669.2 CDI81184.1 - 0.29 11.3 0.2 0.12 12.6 3.4 5.1 4 3 1 5 5 3 0 Virus attachment protein p12 family EphA2_TM PF14575.1 CDI81184.1 - 0.73 10.2 0.0 0.73 10.2 0.0 6.5 3 2 1 4 4 3 0 Ephrin type-A receptor 2 transmembrane domain DUF843 PF05814.6 CDI81184.1 - 0.74 9.6 11.0 1.3 8.8 0.0 3.6 3 1 0 3 3 3 0 Baculovirus protein of unknown function (DUF843) TFIIF_alpha PF05793.7 CDI81184.1 - 1.5 7.1 28.0 0.04 12.2 15.1 1.5 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF4131 PF13567.1 CDI81184.1 - 5.6 6.3 25.0 0.041 13.2 3.5 3.3 2 1 1 3 3 2 0 Domain of unknown function (DUF4131) YfhO PF09586.5 CDI81184.1 - 5.8 4.7 20.0 0.095 10.7 1.0 2.3 2 0 0 2 2 2 0 Bacterial membrane protein YfhO LMBR1 PF04791.11 CDI81184.1 - 7.1 5.0 14.2 23 3.4 9.5 1.9 1 1 1 2 2 2 0 LMBR1-like membrane protein zf-C3HC4_4 PF15227.1 CDI81191.1 - 0.018 14.8 2.7 0.038 13.8 1.9 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING RAP PF08373.5 CDI81211.1 - 1.6e-15 56.6 0.0 2.7e-15 55.8 0.0 1.4 1 0 0 1 1 1 1 RAP domain DUF559 PF04480.7 CDI81211.1 - 0.3 10.7 2.5 0.36 10.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF559) DUF2924 PF11149.3 CDI81211.1 - 1.7 8.6 5.0 9.7 6.2 2.5 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF2924) FeS PF04060.8 CDI81212.1 - 0.011 15.2 6.0 1.1 8.9 0.3 2.9 2 0 0 2 2 2 0 Putative Fe-S cluster MIP-T3 PF10243.4 CDI81213.1 - 1.3 7.4 74.7 2 6.7 51.8 1.3 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Sporozoite_P67 PF05642.6 CDI81218.1 - 1.3e-07 29.9 15.2 1.3e-07 29.9 10.5 1.3 1 1 0 1 1 1 1 Sporozoite P67 surface antigen Activator_LAG-3 PF11498.3 CDI81218.1 - 0.0013 17.5 19.1 0.0013 17.5 13.2 3.1 2 1 1 3 3 3 1 Transcriptional activator LAG-3 SR-25 PF10500.4 CDI81218.1 - 0.011 15.2 6.5 0.011 15.2 4.5 3.1 2 1 1 3 3 3 0 Nuclear RNA-splicing-associated protein SAGA-Tad1 PF12767.2 CDI81218.1 - 0.042 13.5 52.0 0.031 13.9 22.6 2.1 2 0 0 2 2 2 0 Transcriptional regulator of RNA polII, SAGA, subunit Herpes_LMP2 PF07415.6 CDI81218.1 - 4.9 5.6 21.4 0.047 12.2 7.3 2.1 2 0 0 2 2 2 0 Gammaherpesvirus latent membrane protein (LMP2) protein Caldesmon PF02029.10 CDI81218.1 - 5.2 5.3 41.1 0.088 11.2 17.7 2.2 2 0 0 2 2 2 0 Caldesmon CAF-1_p150 PF11600.3 CDI81218.1 - 5.7 6.2 59.6 2.1 7.6 28.7 2.1 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Utp14 PF04615.8 CDI81218.1 - 8.2 4.4 60.0 0.057 11.5 26.9 2.0 2 0 0 2 2 2 0 Utp14 protein CAF-1_p150 PF11600.3 CDI81219.1 - 0.00061 19.2 28.3 0.00075 18.9 19.6 1.1 1 0 0 1 1 1 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal AAA_23 PF13476.1 CDI81219.1 - 0.0017 18.6 7.5 0.0018 18.6 5.2 1.1 1 0 0 1 1 1 1 AAA domain Med15 PF09606.5 CDI81219.1 - 0.0021 16.3 34.6 0.0021 16.3 24.0 1.1 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal PAT1 PF09770.4 CDI81219.1 - 0.0088 14.3 25.7 0.0084 14.4 17.8 1.1 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 SprA-related PF12118.3 CDI81219.1 - 0.01 15.2 35.9 0.016 14.5 24.9 1.3 1 0 0 1 1 1 0 SprA-related family FimP PF09766.4 CDI81219.1 - 0.083 11.9 24.7 0.11 11.6 17.1 1.1 1 0 0 1 1 1 0 Fms-interacting protein DUF737 PF05300.6 CDI81219.1 - 0.11 12.4 18.2 0.14 12.0 12.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF737) eIF-3_zeta PF05091.7 CDI81219.1 - 0.14 10.7 14.2 0.14 10.7 9.9 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) RR_TM4-6 PF06459.7 CDI81219.1 - 0.15 11.9 11.0 0.17 11.7 7.6 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 NARP1 PF12569.3 CDI81219.1 - 0.15 10.7 11.6 0.17 10.6 8.1 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Suf PF05843.9 CDI81219.1 - 0.27 10.9 20.4 0.34 10.6 14.2 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) BTV_NS2 PF04514.7 CDI81219.1 - 0.55 9.0 9.9 0.55 9.0 6.9 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 DUF4407 PF14362.1 CDI81219.1 - 0.7 8.7 14.9 0.79 8.6 10.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) FLO_LFY PF01698.11 CDI81219.1 - 0.78 8.5 16.9 0.86 8.3 11.7 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein Tim54 PF11711.3 CDI81219.1 - 0.94 8.0 9.3 0.93 8.0 6.5 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Corona_nucleoca PF00937.13 CDI81219.1 - 0.98 8.3 28.7 1.2 7.9 19.9 1.0 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein PcfK PF14058.1 CDI81219.1 - 1.5 9.0 18.3 1.9 8.6 12.7 1.2 1 0 0 1 1 1 0 PcfK-like protein DUF853 PF05872.7 CDI81219.1 - 1.6 6.9 8.8 1.6 6.9 6.1 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) VESA1_N PF12785.2 CDI81219.1 - 1.7 7.4 30.6 2 7.3 21.2 1.0 1 0 0 1 1 1 0 Variant erythrocyte surface antigen-1 Hamartin PF04388.7 CDI81219.1 - 1.9 7.0 21.8 2.1 6.8 15.1 1.0 1 0 0 1 1 1 0 Hamartin protein Raftlin PF15250.1 CDI81219.1 - 2.1 6.7 22.2 2.4 6.5 15.4 1.0 1 0 0 1 1 1 0 Raftlin TFIIA PF03153.8 CDI81219.1 - 2.3 8.0 27.8 2.8 7.7 19.2 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit AUX_IAA PF02309.11 CDI81219.1 - 2.6 7.7 17.2 3.4 7.3 11.9 1.2 1 0 0 1 1 1 0 AUX/IAA family Hex_IIIa PF02455.11 CDI81219.1 - 3.7 6.1 15.0 4.2 5.9 10.4 1.0 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) Sec62 PF03839.11 CDI81219.1 - 4.2 6.7 9.6 4.6 6.5 6.6 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 DUF3533 PF12051.3 CDI81219.1 - 4.3 5.9 17.3 4.7 5.8 12.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3533) DUF2126 PF09899.4 CDI81219.1 - 4.6 5.1 9.0 4.5 5.1 6.3 1.0 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) DUF913 PF06025.7 CDI81219.1 - 5.1 5.7 12.5 5.4 5.6 8.7 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DUF3801 PF12687.2 CDI81219.1 - 5.1 6.6 17.1 7.8 6.0 11.8 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3801) Cellulose_synt PF03552.9 CDI81219.1 - 5.5 5.1 14.0 6.4 4.9 9.7 1.0 1 0 0 1 1 1 0 Cellulose synthase DUF4175 PF13779.1 CDI81219.1 - 9.7 3.7 41.4 11 3.5 28.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) SOBP PF15279.1 CDI81230.1 - 2.7 8.2 10.9 3.1 8.0 7.6 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein Hid1 PF12722.2 CDI81230.1 - 3.7 5.0 6.8 3.6 5.1 4.7 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein RLL PF10036.4 CDI81230.1 - 7.9 5.8 10.4 11 5.3 7.2 1.2 1 0 0 1 1 1 0 Putative carnitine deficiency-associated protein PAT1 PF09770.4 CDI81231.1 - 0.0012 17.2 92.9 0.0012 17.2 64.4 1.1 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 DUF3675 PF12428.3 CDI81234.1 - 0.0037 17.4 3.4 0.031 14.5 0.5 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3675) BatD PF13584.1 CDI81234.1 - 0.0055 15.3 12.0 0.013 14.1 3.1 2.0 2 0 0 2 2 2 2 Oxygen tolerance Yip1 PF04893.12 CDI81234.1 - 0.011 15.2 3.0 1.7 8.1 0.0 3.0 2 1 0 3 3 3 0 Yip1 domain TMEM154 PF15102.1 CDI81234.1 - 0.012 15.3 11.4 0.27 10.9 1.2 2.3 2 0 0 2 2 2 0 TMEM154 protein family Herpes_gE PF02480.11 CDI81234.1 - 0.031 12.5 2.4 0.062 11.5 0.2 1.9 1 1 1 2 2 2 0 Alphaherpesvirus glycoprotein E ABC_membrane PF00664.18 CDI81234.1 - 0.07 12.5 2.6 1 8.7 0.0 2.2 1 1 0 2 2 2 0 ABC transporter transmembrane region DC_STAMP PF07782.8 CDI81234.1 - 0.075 12.6 6.8 0.14 11.7 4.3 1.8 1 1 0 1 1 1 0 DC-STAMP-like protein DUF3357 PF11837.3 CDI81234.1 - 0.22 11.4 16.1 1.7 8.5 5.4 3.3 1 1 2 3 3 3 0 Domain of unknown function (DUF3357) LMBR1 PF04791.11 CDI81234.1 - 0.32 9.5 8.7 0.46 9.0 6.1 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein 7tm_1 PF00001.16 CDI81234.1 - 0.51 9.4 10.0 2.9 6.9 6.6 2.1 1 1 1 2 2 2 0 7 transmembrane receptor (rhodopsin family) Conotoxin PF02950.12 CDI81234.1 - 0.96 10.2 20.4 1.2 10.0 1.0 3.4 3 1 0 3 3 3 0 Conotoxin TFIIA PF03153.8 CDI81234.1 - 1.4 8.7 36.0 1.8 8.4 24.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF2721 PF11026.3 CDI81234.1 - 1.5 8.4 8.6 0.94 9.1 2.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) Sex_peptide PF08138.6 CDI81234.1 - 1.5 8.6 6.7 7.1 6.5 0.2 2.9 3 0 0 3 3 3 0 Sex peptide (SP) family EphA2_TM PF14575.1 CDI81234.1 - 1.8 8.9 0.0 1.8 8.9 0.0 4.0 2 1 2 4 4 4 0 Ephrin type-A receptor 2 transmembrane domain DUF912 PF06024.7 CDI81234.1 - 1.9 8.6 13.9 0.29 11.1 1.8 2.4 1 1 1 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF4307 PF14155.1 CDI81234.1 - 2.1 8.1 0.0 2.1 8.1 0.0 3.9 1 1 3 4 4 4 0 Domain of unknown function (DUF4307) DUF966 PF06136.8 CDI81234.1 - 3.5 6.9 18.7 4.9 6.4 12.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Chordopox_A13L PF05961.6 CDI81234.1 - 3.8 7.5 0.0 3.8 7.5 0.0 2.9 4 0 0 4 4 3 0 Chordopoxvirus A13L protein Citrate_synt PF00285.16 CDI81234.1 - 4.2 5.9 13.7 1.4 7.5 6.8 1.8 1 1 1 2 2 2 0 Citrate synthase DivIC PF04977.10 CDI81234.1 - 4.9 6.7 34.4 4 6.9 7.6 3.2 3 0 0 3 3 3 0 Septum formation initiator UPF0233 PF06781.7 CDI81234.1 - 5.4 6.7 5.9 8.9 6.0 0.4 2.7 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0233) DUF4401 PF14351.1 CDI81234.1 - 7.8 5.3 11.4 0.5 9.2 2.7 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4401) FIST_C PF10442.4 CDI81234.1 - 8.6 6.3 7.8 22 5.0 0.3 2.3 2 0 0 2 2 2 0 FIST C domain AAA PF00004.24 CDI81238.1 - 4.7e-07 30.0 11.1 0.00031 20.9 0.0 4.5 4 1 0 4 4 4 2 ATPase family associated with various cellular activities (AAA) Ribosomal_60s PF00428.14 CDI81238.1 - 0.0042 17.4 10.1 0.026 14.9 3.4 7.0 6 1 0 6 6 6 4 60s Acidic ribosomal protein CDC45 PF02724.9 CDI81239.1 - 0.00034 18.7 10.1 0.00041 18.5 7.0 1.1 1 0 0 1 1 1 1 CDC45-like protein RICTOR_N PF14664.1 CDI81239.1 - 0.0036 15.9 4.5 0.44 9.0 0.3 2.2 2 0 0 2 2 2 2 Rapamycin-insensitive companion of mTOR, N-term DUF1510 PF07423.6 CDI81239.1 - 0.025 13.9 18.2 0.036 13.4 12.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) SGT1 PF07093.6 CDI81239.1 - 0.14 10.4 16.7 0.16 10.2 11.5 1.1 1 0 0 1 1 1 0 SGT1 protein PRP1_N PF06424.7 CDI81239.1 - 0.16 12.2 15.1 0.24 11.6 10.4 1.2 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal Hid1 PF12722.2 CDI81239.1 - 0.17 9.5 15.3 0.21 9.2 10.6 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Ycf1 PF05758.7 CDI81239.1 - 0.21 9.2 16.5 0.26 8.9 11.5 1.0 1 0 0 1 1 1 0 Ycf1 SID-1_RNA_chan PF13965.1 CDI81239.1 - 0.25 9.4 8.8 0.32 9.1 6.1 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DUF4045 PF13254.1 CDI81239.1 - 0.32 10.2 15.8 0.4 9.9 10.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Endostatin PF06482.6 CDI81239.1 - 0.32 10.3 17.4 0.23 10.8 11.2 1.3 1 1 0 1 1 1 0 Collagenase NC10 and Endostatin Miff PF05644.6 CDI81239.1 - 0.44 10.1 10.5 0.55 9.8 7.3 1.3 1 0 0 1 1 1 0 Mitochondrial and peroxisomal fission factor Mff Mem_trans PF03547.13 CDI81239.1 - 0.47 8.6 5.5 0.67 8.1 3.8 1.2 1 0 0 1 1 1 0 Membrane transport protein Neur_chan_memb PF02932.11 CDI81239.1 - 0.53 10.1 19.8 0.92 9.3 13.7 1.4 1 1 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF572 PF04502.8 CDI81239.1 - 0.63 9.2 19.4 0.85 8.7 13.4 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) FAM60A PF15396.1 CDI81239.1 - 1 9.0 13.9 1.6 8.4 9.6 1.4 1 0 0 1 1 1 0 Protein Family FAM60A Tim54 PF11711.3 CDI81239.1 - 1 7.8 10.0 1.3 7.4 6.9 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 PLRV_ORF5 PF01690.12 CDI81239.1 - 1.1 8.2 16.9 1.4 7.9 11.7 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein SET PF00856.23 CDI81239.1 - 1.1 9.5 4.5 1.7 8.8 3.1 1.5 1 1 0 1 1 1 0 SET domain Parvo_coat PF00740.13 CDI81239.1 - 1.2 8.0 19.0 1.4 7.8 13.2 1.1 1 0 0 1 1 1 0 Parvovirus coat protein VP2 PCEMA1 PF07418.6 CDI81239.1 - 1.4 8.1 10.4 1.7 7.9 7.2 1.1 1 0 0 1 1 1 0 Acidic phosphoprotein precursor PCEMA1 HlyD_2 PF12700.2 CDI81239.1 - 1.6 7.8 16.1 1.8 7.6 11.1 1.1 1 0 0 1 1 1 0 HlyD family secretion protein RR_TM4-6 PF06459.7 CDI81239.1 - 2 8.2 18.3 3.3 7.5 12.7 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SAMP PF05924.6 CDI81239.1 - 2.1 7.6 6.0 11 5.3 0.0 2.9 3 0 0 3 3 3 0 SAMP Motif Pox_Ag35 PF03286.9 CDI81239.1 - 3.4 7.1 15.2 4.9 6.6 10.5 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DUF2347 PF09804.4 CDI81239.1 - 3.4 6.8 11.2 5.3 6.2 7.8 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2347) LMBR1 PF04791.11 CDI81239.1 - 3.8 5.9 6.4 4 5.9 4.4 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein eIF-3_zeta PF05091.7 CDI81239.1 - 3.9 5.9 19.2 4.9 5.6 13.3 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Presenilin PF01080.12 CDI81239.1 - 4.4 6.0 11.0 7 5.3 7.6 1.3 1 0 0 1 1 1 0 Presenilin Sporozoite_P67 PF05642.6 CDI81239.1 - 4.5 4.9 6.8 5.4 4.7 4.7 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF1675 PF07897.6 CDI81239.1 - 5.1 6.8 12.8 6.7 6.4 8.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) DUF4011 PF13195.1 CDI81239.1 - 6.5 6.7 15.9 11 5.9 11.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4011) HAUS6_N PF14661.1 CDI81239.1 - 6.5 6.0 28.7 0.31 10.3 0.1 2.3 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus Ndc1_Nup PF09531.5 CDI81239.1 - 6.5 5.0 20.3 8.7 4.6 14.0 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup NTP_transf_2 PF01909.18 CDI81245.1 - 3 8.2 0.0 5.4 7.4 0.0 1.3 1 0 0 1 1 1 0 Nucleotidyltransferase domain Peptidase_S49_N PF08496.5 CDI81246.1 - 0.0048 16.7 12.8 0.17 11.6 1.0 3.1 3 0 0 3 3 3 2 Peptidase family S49 N-terminal Tmemb_9 PF05434.6 CDI81246.1 - 0.005 16.6 5.6 0.005 16.6 3.8 3.4 3 0 0 3 3 2 1 TMEM9 DUF1510 PF07423.6 CDI81246.1 - 0.048 13.0 0.2 0.048 13.0 0.1 3.6 2 1 0 3 3 3 0 Protein of unknown function (DUF1510) TRAP_alpha PF03896.11 CDI81246.1 - 0.06 12.3 4.3 0.18 10.7 0.3 2.3 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit G0-G1_switch_2 PF15103.1 CDI81246.1 - 0.083 13.1 11.1 0.19 11.9 1.0 2.6 2 0 0 2 2 2 0 G0/G1 switch protein 2 GBP_C PF02841.9 CDI81246.1 - 0.34 10.0 26.1 0.42 9.7 9.0 2.2 2 0 0 2 2 2 0 Guanylate-binding protein, C-terminal domain DUF4446 PF14584.1 CDI81246.1 - 0.4 10.5 15.1 0.023 14.5 2.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF4446) MAT1 PF06391.8 CDI81246.1 - 0.59 9.6 18.0 1.3 8.5 4.6 2.5 2 0 0 2 2 2 0 CDK-activating kinase assembly factor MAT1 UPF0118 PF01594.11 CDI81246.1 - 1.1 8.1 17.3 0.19 10.6 1.7 2.3 2 0 0 2 2 2 0 Domain of unknown function DUF20 Tetraspannin PF00335.15 CDI81246.1 - 1.2 8.3 26.4 1.5e+04 -6.3 18.3 2.8 1 1 0 1 1 0 0 Tetraspanin family DUF106 PF01956.11 CDI81246.1 - 2.1 7.8 8.5 17 4.9 0.1 2.8 2 1 1 3 3 3 0 Integral membrane protein DUF106 Endonuc_Holl PF10107.4 CDI81246.1 - 3.1 7.4 12.0 0.59 9.8 1.0 2.6 2 0 0 2 2 2 0 Endonuclease related to archaeal Holliday junction resolvase Zea_mays_MuDR PF05928.6 CDI81247.1 - 0.017 14.5 7.7 0.021 14.2 5.3 1.1 1 0 0 1 1 1 0 Zea mays MURB-like protein (MuDR) Med15 PF09606.5 CDI81247.1 - 0.062 11.5 50.1 0.072 11.2 34.7 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF2232 PF09991.4 CDI81247.1 - 0.076 11.9 1.6 0.098 11.6 1.1 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) DUF2215 PF10225.4 CDI81247.1 - 0.4 10.0 10.3 0.5 9.7 7.2 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) PAT1 PF09770.4 CDI81247.1 - 0.91 7.6 43.5 0.97 7.5 30.2 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 FHIPEP PF00771.15 CDI81247.1 - 1.8 6.7 14.6 2 6.6 10.1 1.1 1 0 0 1 1 1 0 FHIPEP family FAM60A PF15396.1 CDI81247.1 - 2.5 7.8 14.4 2.5 7.7 10.0 1.2 1 0 0 1 1 1 0 Protein Family FAM60A DDHD PF02862.12 CDI81247.1 - 2.6 7.7 14.9 3 7.5 10.3 1.2 1 0 0 1 1 1 0 DDHD domain DUF4179 PF13786.1 CDI81247.1 - 2.8 8.2 10.8 74 3.6 7.5 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4179) Hid1 PF12722.2 CDI81247.1 - 4.3 4.8 18.4 4.2 4.9 12.7 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Ycf1 PF05758.7 CDI81247.1 - 4.7 4.7 16.2 4.7 4.7 11.2 1.0 1 0 0 1 1 1 0 Ycf1 Neur_chan_memb PF02932.11 CDI81247.1 - 4.8 6.9 15.0 5.2 6.8 10.4 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Peptidase_S15 PF02129.13 CDI81247.1 - 5.4 6.3 18.2 7.5 5.8 12.6 1.3 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) DUF342 PF03961.8 CDI81247.1 - 6.1 5.1 10.5 6.3 5.1 7.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) MCM PF00493.18 CDI81249.1 - 0.028 13.2 0.6 0.028 13.2 0.4 1.6 2 0 0 2 2 2 0 MCM2/3/5 family CPSF_A PF03178.10 CDI81249.1 - 0.083 11.9 2.4 0.084 11.9 1.7 1.2 1 0 0 1 1 1 0 CPSF A subunit region Muted PF14942.1 CDI81249.1 - 0.46 10.3 19.1 0.65 9.8 13.2 1.3 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein APG6 PF04111.7 CDI81249.1 - 1.6 7.7 23.5 1.9 7.4 16.3 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 RtcB PF01139.12 CDI81249.1 - 1.8 7.4 9.0 2.2 7.1 6.3 1.0 1 0 0 1 1 1 0 tRNA-splicing ligase RtcB AAA_23 PF13476.1 CDI81249.1 - 2.2 8.5 21.4 2.8 8.2 14.9 1.1 1 0 0 1 1 1 0 AAA domain FLO_LFY PF01698.11 CDI81249.1 - 2.8 6.6 13.9 3.1 6.5 9.6 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein Phe_hydrox_dim PF07976.7 CDI81249.1 - 6.2 6.3 9.5 8.2 5.9 6.6 1.3 1 0 0 1 1 1 0 Phenol hydroxylase, C-terminal dimerisation domain SR-25 PF10500.4 CDI81254.1 - 0.00032 20.2 24.5 0.00039 19.9 11.8 2.4 2 0 0 2 2 2 2 Nuclear RNA-splicing-associated protein DUF4589 PF15252.1 CDI81254.1 - 0.022 14.5 17.5 0.032 14.0 12.1 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4589) Raftlin PF15250.1 CDI81254.1 - 2 6.8 19.7 1.5 7.2 13.1 1.2 1 1 0 1 1 1 0 Raftlin Robl_LC7 PF03259.12 CDI81254.1 - 3.7 7.1 6.8 2.4 7.7 0.3 2.7 3 0 0 3 3 3 0 Roadblock/LC7 domain Ribosomal_60s PF00428.14 CDI81254.1 - 5.1 7.5 18.5 0.18 12.2 1.8 2.7 2 1 0 2 2 2 0 60s Acidic ribosomal protein SID-1_RNA_chan PF13965.1 CDI81254.1 - 6.2 4.8 6.9 7.6 4.5 4.8 1.3 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Defensin_big PF14862.1 CDI81254.1 - 8.6 6.5 6.7 18 5.5 0.2 2.4 2 0 0 2 2 2 0 Big defensin DEPP PF15343.1 CDI81266.1 - 0.0017 17.9 1.1 0.0019 17.8 0.8 1.0 1 0 0 1 1 1 1 Decidual protein induced by progesterone family Mito_fiss_reg PF05308.6 CDI81266.1 - 0.054 12.8 2.9 0.058 12.7 2.0 1.0 1 0 0 1 1 1 0 Mitochondrial fission regulator LptC PF06835.8 CDI81266.1 - 0.32 10.3 5.9 0.4 10.0 4.1 1.0 1 0 0 1 1 1 0 Lipopolysaccharide-assembly, LptC-related Mucin PF01456.12 CDI81266.1 - 0.88 9.3 12.1 0.94 9.2 8.4 1.0 1 0 0 1 1 1 0 Mucin-like glycoprotein Pex14_N PF04695.8 CDI81266.1 - 0.99 9.4 10.2 1.2 9.2 7.0 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region LAP1C PF05609.7 CDI81266.1 - 1.1 7.8 6.6 1.3 7.6 4.5 1.0 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Mei5 PF10376.4 CDI81266.1 - 4.7 6.6 10.0 5.3 6.5 7.0 1.0 1 0 0 1 1 1 0 Double-strand recombination repair protein DUF822 PF05687.8 CDI81266.1 - 5.6 7.3 8.1 6.2 7.1 5.6 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF822) DNA_pol_viral_N PF00242.12 CDI81266.1 - 7.8 5.4 9.6 8.6 5.2 6.6 1.0 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain DUF89 PF01937.14 CDI81282.1 - 2.8e-16 59.2 0.6 4.3e-15 55.3 0.4 2.0 1 1 0 1 1 1 1 Protein of unknown function DUF89 CDK2AP PF09806.4 CDI81282.1 - 7.1e-05 23.1 9.0 9.7e-05 22.6 6.3 1.1 1 0 0 1 1 1 1 Cyclin-dependent kinase 2-associated protein Med15 PF09606.5 CDI81282.1 - 0.0043 15.3 11.3 0.005 15.1 7.8 1.2 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal DUF572 PF04502.8 CDI81282.1 - 0.029 13.5 4.0 0.038 13.2 2.8 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF4175 PF13779.1 CDI81282.1 - 0.036 11.7 9.7 0.039 11.6 6.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) FimP PF09766.4 CDI81282.1 - 0.068 12.2 6.5 0.37 9.8 4.9 1.7 2 0 0 2 2 2 0 Fms-interacting protein SSP160 PF06933.6 CDI81282.1 - 0.26 9.1 11.6 0.29 9.0 8.1 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DNA_pol_viral_N PF00242.12 CDI81282.1 - 0.3 10.0 10.2 0.39 9.7 7.1 1.1 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain Trs65 PF12735.2 CDI81282.1 - 0.38 10.0 12.8 0.53 9.5 8.9 1.1 1 0 0 1 1 1 0 TRAPP trafficking subunit Trs65 Sporozoite_P67 PF05642.6 CDI81282.1 - 0.57 7.9 7.7 0.83 7.4 5.4 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Herpes_DNAp_acc PF04929.7 CDI81282.1 - 0.83 8.5 8.1 1.3 7.8 5.6 1.3 1 0 0 1 1 1 0 Herpes DNA replication accessory factor BMF PF15185.1 CDI81282.1 - 0.88 8.8 8.8 0.061 12.6 1.0 2.0 2 0 0 2 2 2 0 Bcl-2-modifying factor, apoptosis Lin-8 PF03353.10 CDI81282.1 - 1.3 8.2 7.3 1.6 7.9 5.1 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Spc7_N PF15402.1 CDI81282.1 - 2.5 6.0 12.1 3.2 5.6 8.4 1.0 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 NPR3 PF03666.8 CDI81282.1 - 2.7 6.4 9.3 3.8 5.9 6.5 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Apt1 PF10351.4 CDI81282.1 - 2.9 6.6 14.0 4.5 6.0 9.7 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain RAP1 PF07218.6 CDI81282.1 - 4 5.4 14.3 5.1 5.0 9.9 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Glycos_transf_2 PF00535.21 CDI81285.1 - 1.1e-22 80.4 0.0 1.6e-22 80.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_7C PF02709.9 CDI81285.1 - 3.1e-11 42.5 0.3 8.4e-11 41.1 0.1 1.8 2 0 0 2 2 2 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_3 PF13641.1 CDI81285.1 - 1.8e-10 41.0 0.0 3.5e-10 40.0 0.0 1.4 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.4 CDI81285.1 - 3.6e-08 32.8 0.0 8.9e-08 31.5 0.0 1.7 2 1 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 CDI81285.1 - 0.011 15.0 0.0 0.021 14.1 0.0 1.5 1 1 0 1 1 1 0 Glycosyl transferase family 21 Glyco_trans_2_3 PF13632.1 CDI81285.1 - 0.016 14.9 0.1 0.028 14.1 0.1 1.4 1 0 0 1 1 1 0 Glycosyl transferase family group 2 Shadoo PF14999.1 CDI81286.1 - 0.0018 18.1 3.9 0.0018 18.1 2.7 1.5 2 0 0 2 2 1 1 Shadow of prion protein, neuroprotective DUF3984 PF13136.1 CDI81286.1 - 0.058 12.6 15.8 0.072 12.3 10.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3984) Pox_Ag35 PF03286.9 CDI81286.1 - 0.11 11.9 9.9 0.13 11.8 6.9 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein BTV_NS2 PF04514.7 CDI81286.1 - 0.21 10.4 14.7 0.22 10.3 10.2 1.0 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 DUF1510 PF07423.6 CDI81286.1 - 0.21 10.9 17.4 0.23 10.8 12.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DUF4045 PF13254.1 CDI81286.1 - 0.34 10.1 15.4 0.37 10.0 10.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Med15 PF09606.5 CDI81286.1 - 0.36 8.9 60.2 0.44 8.6 41.7 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal PAT1 PF09770.4 CDI81286.1 - 0.38 8.9 42.7 0.42 8.8 29.6 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Peptidase_S49_N PF08496.5 CDI81286.1 - 0.57 9.9 14.9 0.79 9.4 10.3 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Raftlin PF15250.1 CDI81286.1 - 0.68 8.4 15.8 0.75 8.2 10.9 1.0 1 0 0 1 1 1 0 Raftlin DUF3450 PF11932.3 CDI81286.1 - 0.68 9.1 38.8 0.81 8.9 26.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Cellulose_synt PF03552.9 CDI81286.1 - 0.74 8.0 6.5 0.76 7.9 4.5 1.0 1 0 0 1 1 1 0 Cellulose synthase Zip PF02535.17 CDI81286.1 - 0.79 8.6 5.1 0.89 8.4 3.6 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter FHIPEP PF00771.15 CDI81286.1 - 0.83 7.9 14.3 0.98 7.6 9.9 1.1 1 0 0 1 1 1 0 FHIPEP family BORG_CEP PF14957.1 CDI81286.1 - 0.96 10.3 9.5 1.3 9.9 6.6 1.3 1 0 0 1 1 1 0 Cdc42 effector Membralin PF09746.4 CDI81286.1 - 1.2 8.1 7.1 1.2 8.1 4.9 1.0 1 0 0 1 1 1 0 Tumour-associated protein eIF-3_zeta PF05091.7 CDI81286.1 - 1.7 7.1 23.8 1.8 7.0 16.5 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) SAGA-Tad1 PF12767.2 CDI81286.1 - 1.7 8.2 19.8 2.1 7.9 13.7 1.1 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit AUX_IAA PF02309.11 CDI81286.1 - 1.8 8.2 14.0 2 8.0 9.7 1.1 1 0 0 1 1 1 0 AUX/IAA family Spore_coat_CotO PF14153.1 CDI81286.1 - 1.9 7.9 25.8 2.1 7.7 17.9 1.2 1 0 0 1 1 1 0 Spore coat protein CotO PPP4R2 PF09184.6 CDI81286.1 - 1.9 7.9 13.0 2.1 7.8 9.0 1.1 1 0 0 1 1 1 0 PPP4R2 Pal1 PF08316.6 CDI81286.1 - 2.2 8.7 11.3 2.9 8.3 7.8 1.2 1 0 0 1 1 1 0 Pal1 cell morphology protein DUF3987 PF13148.1 CDI81286.1 - 2.7 6.4 15.4 3.5 6.0 10.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) FAM60A PF15396.1 CDI81286.1 - 2.7 7.6 16.8 3.2 7.4 11.6 1.0 1 0 0 1 1 1 0 Protein Family FAM60A CDK5_activator PF03261.10 CDI81286.1 - 2.9 7.1 16.3 3.1 7.0 11.3 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein DUF3591 PF12157.3 CDI81286.1 - 3.1 6.0 17.9 3.5 5.9 12.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3591) Parvo_coat PF00740.13 CDI81286.1 - 3.2 6.5 20.2 3.5 6.4 14.0 1.0 1 0 0 1 1 1 0 Parvovirus coat protein VP2 Bac_luciferase PF00296.15 CDI81286.1 - 3.2 6.7 12.3 4 6.4 8.5 1.1 1 0 0 1 1 1 0 Luciferase-like monooxygenase GAGA_bind PF06217.7 CDI81286.1 - 3.3 7.5 17.8 3.7 7.4 12.4 1.0 1 0 0 1 1 1 0 GAGA binding protein-like family Paf1 PF03985.8 CDI81286.1 - 3.4 6.3 21.3 3.9 6.1 14.7 1.0 1 0 0 1 1 1 0 Paf1 Ycf1 PF05758.7 CDI81286.1 - 3.5 5.2 18.7 3.7 5.1 13.0 1.0 1 0 0 1 1 1 0 Ycf1 FLO_LFY PF01698.11 CDI81286.1 - 3.7 6.3 18.0 4.5 6.0 12.4 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein Cyto_heme_lyase PF01265.12 CDI81286.1 - 3.8 7.0 20.0 4.3 6.8 13.8 1.0 1 0 0 1 1 1 0 Cytochrome c/c1 heme lyase DUF2146 PF10220.4 CDI81286.1 - 3.8 5.3 19.0 4.5 5.1 13.2 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2146) Neur_chan_memb PF02932.11 CDI81286.1 - 4.2 7.1 12.3 4.6 7.0 8.5 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region SpoVR PF04293.8 CDI81286.1 - 4.2 5.6 16.1 4.5 5.5 11.1 1.1 1 0 0 1 1 1 0 SpoVR like protein DUF4220 PF13968.1 CDI81286.1 - 4.3 6.3 10.7 4.7 6.2 7.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4220) PBP1_TM PF14812.1 CDI81286.1 - 4.3 7.7 12.3 7.5 6.9 8.5 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF4446 PF14584.1 CDI81286.1 - 4.5 7.0 11.4 5.2 6.8 7.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) Spc7_N PF15402.1 CDI81286.1 - 4.6 5.1 22.2 5.3 4.9 15.4 1.0 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 RNA_pol_Rpb1_5 PF04998.12 CDI81286.1 - 4.7 6.3 10.7 5.5 6.1 7.4 1.0 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 Paramyxo_ncap PF00973.14 CDI81286.1 - 4.7 5.7 16.5 5.2 5.6 11.5 1.0 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Mem_trans PF03547.13 CDI81286.1 - 4.7 5.3 8.4 5.2 5.2 5.9 1.1 1 0 0 1 1 1 0 Membrane transport protein Band_3_cyto PF07565.8 CDI81286.1 - 4.9 6.5 17.7 6.1 6.2 12.2 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain DUF2370 PF10176.4 CDI81286.1 - 5 6.3 11.5 5.8 6.1 8.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) CDC45 PF02724.9 CDI81286.1 - 5.1 4.9 16.3 5.5 4.8 11.3 1.0 1 0 0 1 1 1 0 CDC45-like protein DUF2126 PF09899.4 CDI81286.1 - 5.2 4.9 13.0 5.6 4.8 9.0 1.0 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) DDHD PF02862.12 CDI81286.1 - 5.8 6.6 18.0 6.6 6.4 12.5 1.1 1 0 0 1 1 1 0 DDHD domain Bud13 PF09736.4 CDI81286.1 - 6.2 7.0 25.0 8 6.7 17.4 1.2 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex APG6 PF04111.7 CDI81286.1 - 6.4 5.7 22.2 6.6 5.6 15.4 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Spore_YhcN_YlaJ PF09580.5 CDI81286.1 - 7 6.7 19.7 8 6.5 13.6 1.2 1 0 0 1 1 1 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) AMP-binding PF00501.23 CDI81286.1 - 7.1 4.8 6.8 7.9 4.7 4.7 1.1 1 0 0 1 1 1 0 AMP-binding enzyme Gti1_Pac2 PF09729.4 CDI81286.1 - 7.5 6.3 13.5 10 5.9 9.4 1.2 1 0 0 1 1 1 0 Gti1/Pac2 family YABBY PF04690.8 CDI81286.1 - 7.7 6.7 10.8 9.7 6.3 7.5 1.4 1 0 0 1 1 1 0 YABBY protein FliP PF00813.15 CDI81286.1 - 8 6.1 9.6 8.4 6.0 6.6 1.1 1 0 0 1 1 1 0 FliP family GBP_C PF02841.9 CDI81286.1 - 8.3 5.4 29.2 11 5.0 20.3 1.1 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain Helicase_RecD PF05127.9 CDI81286.1 - 8.4 5.9 12.0 9.5 5.8 8.3 1.1 1 0 0 1 1 1 0 Helicase Presenilin PF01080.12 CDI81286.1 - 8.4 5.1 14.0 10 4.8 9.7 1.0 1 0 0 1 1 1 0 Presenilin MRP-S31 PF15433.1 CDI81286.1 - 8.7 5.6 29.2 18 4.6 20.4 1.4 1 1 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 RR_TM4-6 PF06459.7 CDI81286.1 - 8.8 6.1 20.8 10 5.9 14.4 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 PMSI1 PF15322.1 CDI81286.1 - 8.8 5.3 17.3 10 5.1 12.0 1.0 1 0 0 1 1 1 0 Protein missing in infertile sperm 1, putative Gag_spuma PF03276.9 CDI81286.1 - 8.9 4.5 35.3 11 4.2 24.5 1.1 1 0 0 1 1 1 0 Spumavirus gag protein TFIIA PF03153.8 CDI81286.1 - 9.6 5.9 37.5 12 5.6 26.0 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF2215 PF10225.4 CDI81286.1 - 9.9 5.5 8.9 12 5.2 6.2 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) Peptidase_S15 PF02129.13 CDI81286.1 - 9.9 5.4 16.8 13 5.0 11.7 1.1 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) DUF3357 PF11837.3 CDI81288.1 - 0.26 11.1 4.8 4.7 7.1 0.0 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF3357) Sporozoite_P67 PF05642.6 CDI81294.1 - 0.0099 13.8 16.9 0.014 13.3 11.7 1.1 1 0 0 1 1 1 1 Sporozoite P67 surface antigen Nucleoplasmin PF03066.10 CDI81294.1 - 0.095 12.2 2.0 0.19 11.2 1.4 1.4 1 0 0 1 1 1 0 Nucleoplasmin NOA36 PF06524.7 CDI81294.1 - 0.24 10.6 3.8 0.44 9.7 2.7 1.3 1 0 0 1 1 1 0 NOA36 protein CENP-B_dimeris PF09026.5 CDI81294.1 - 0.79 9.9 9.2 1.7 8.9 6.4 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Cpn10 PF00166.16 CDI81297.1 - 3e-25 87.9 0.3 1.7e-16 59.8 0.0 3.1 3 0 0 3 3 3 2 Chaperonin 10 Kd subunit Myco_19_kDa PF05481.7 CDI81297.1 - 1.1 9.0 5.5 1.9 8.3 3.8 1.3 1 0 0 1 1 1 0 Mycobacterium 19 kDa lipoprotein antigen DUF1180 PF06679.7 CDI81297.1 - 1.8 8.3 5.7 2.4 8.0 2.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) SR-25 PF10500.4 CDI81297.1 - 9.7 5.5 8.6 14 5.0 6.0 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Neur_chan_memb PF02932.11 CDI81298.1 - 0.018 14.9 1.1 0.038 13.8 0.8 1.6 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF4293 PF14126.1 CDI81298.1 - 0.054 13.4 0.3 0.054 13.4 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4293) CRPA PF05745.6 CDI81298.1 - 0.077 12.7 0.3 0.32 10.7 0.2 2.0 1 0 0 1 1 1 0 Chlamydia 15 kDa cysteine-rich outer membrane protein (CRPA) CAML PF14963.1 CDI81298.1 - 0.083 12.2 7.0 0.16 11.2 4.9 1.4 1 0 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand Mem_trans PF03547.13 CDI81298.1 - 0.2 9.9 16.1 0.56 8.4 11.2 1.8 1 1 0 1 1 1 0 Membrane transport protein Lin-8 PF03353.10 CDI81298.1 - 0.43 9.8 3.0 0.91 8.7 2.1 1.6 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist DUF912 PF06024.7 CDI81298.1 - 2.8 8.0 8.6 91 3.1 5.9 3.0 1 1 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Hid1 PF12722.2 CDI81298.1 - 6.2 4.3 22.2 9.1 3.8 15.4 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein TFIIA PF03153.8 CDI81298.1 - 8.9 6.0 26.1 16 5.2 18.1 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Helicase_C_2 PF13307.1 CDI81300.1 - 1.2e-16 61.1 0.0 1.4e-16 60.9 0.0 1.1 1 0 0 1 1 1 1 Helicase C-terminal domain Ribosomal_60s PF00428.14 CDI81300.1 - 0.15 12.4 9.8 0.33 11.3 6.8 1.7 1 0 0 1 1 1 0 60s Acidic ribosomal protein PIH1 PF08190.7 CDI81305.1 - 1.4e-07 31.2 1.8 2.2e-05 24.0 0.0 2.1 2 0 0 2 2 2 2 pre-RNA processing PIH1/Nop17 Rsc14 PF08586.5 CDI81305.1 - 0.0084 16.5 0.4 0.014 15.9 0.3 1.3 1 0 0 1 1 1 1 RSC complex, Rsc14/Ldb7 subunit SMN PF06003.7 CDI81305.1 - 0.012 14.7 0.3 0.016 14.3 0.2 1.2 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) His_Phos_2 PF00328.17 CDI81305.1 - 0.022 14.1 0.7 0.025 13.9 0.5 1.0 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 2) Tricho_coat PF05892.6 CDI81305.1 - 0.039 13.1 0.2 0.052 12.7 0.1 1.1 1 0 0 1 1 1 0 Trichovirus coat protein SR-25 PF10500.4 CDI81326.1 - 0.002 17.6 18.6 0.002 17.6 12.9 2.3 1 1 1 2 2 2 1 Nuclear RNA-splicing-associated protein Secretin_N_2 PF07655.8 CDI81326.1 - 0.7 10.3 26.9 2.7 8.4 10.0 2.2 2 0 0 2 2 2 0 Secretin N-terminal domain PAT1 PF09770.4 CDI81326.1 - 1.5 6.9 17.7 1.4 7.0 12.3 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Claudin_2 PF13903.1 CDI81326.1 - 2.2 7.9 7.5 3.2 7.3 2.6 2.2 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction Auxin_canalis PF05703.6 CDI81326.1 - 6.7 6.4 27.2 7.7 6.2 15.7 2.4 1 1 1 2 2 2 0 Auxin canalisation DUF2201_N PF13203.1 CDI81333.1 - 0.35 10.0 21.1 0.0052 16.0 6.8 2.0 2 0 0 2 2 2 0 Putative metallopeptidase domain SM-ATX PF14438.1 CDI81333.1 - 0.36 10.8 0.0 0.36 10.8 0.0 1.8 2 0 0 2 2 2 0 Ataxin 2 SM domain TFIIA PF03153.8 CDI81333.1 - 0.79 9.5 38.7 1.1 9.0 26.8 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit tRNA_synt_1c_R2 PF04557.10 CDI81333.1 - 1.7 9.3 13.6 0.064 13.9 3.2 2.2 2 0 0 2 2 2 0 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 DUF533 PF04391.7 CDI81333.1 - 4.6 6.5 25.1 2.6 7.3 9.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF533) PRP1_N PF06424.7 CDI81333.1 - 5.6 7.2 18.7 13 6.1 0.2 2.4 2 1 0 2 2 2 0 PRP1 splicing factor, N-terminal FAM60A PF15396.1 CDI81333.1 - 8.4 6.0 13.7 1.1 8.9 3.9 2.0 2 0 0 2 2 2 0 Protein Family FAM60A LMBR1 PF04791.11 CDI81338.1 - 0.014 14.0 0.1 0.26 9.8 0.0 2.7 1 1 1 2 2 2 0 LMBR1-like membrane protein SAPS PF04499.10 CDI81338.1 - 0.03 12.9 18.5 0.0045 15.6 2.2 3.0 3 0 0 3 3 3 0 SIT4 phosphatase-associated protein DDHD PF02862.12 CDI81338.1 - 3.7 7.2 28.9 2.3 7.9 0.5 3.3 3 0 0 3 3 3 0 DDHD domain SR-25 PF10500.4 CDI81346.1 - 0.0007 19.1 30.2 0.00093 18.7 20.9 1.2 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein AA_permease_N PF08403.5 CDI81346.1 - 0.0096 15.2 0.1 0.0096 15.2 0.0 2.3 2 1 0 2 2 2 1 Amino acid permease N-terminal TATR PF03430.8 CDI81346.1 - 0.14 10.8 12.7 0.15 10.6 8.8 1.0 1 0 0 1 1 1 0 Trans-activating transcriptional regulator DUF1777 PF08648.7 CDI81346.1 - 0.15 11.7 21.8 0.19 11.4 15.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) DNA_pol_viral_N PF00242.12 CDI81346.1 - 0.4 9.6 14.0 0.46 9.4 9.7 1.0 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain Nucleo_P87 PF07267.6 CDI81346.1 - 0.53 8.9 13.9 0.62 8.6 9.6 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 DUF1510 PF07423.6 CDI81346.1 - 0.61 9.4 23.1 0.82 8.9 16.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DDHD PF02862.12 CDI81346.1 - 0.77 9.5 13.5 1.1 9.0 9.4 1.3 1 0 0 1 1 1 0 DDHD domain Med19 PF10278.4 CDI81346.1 - 0.9 9.1 31.4 0.22 11.2 19.5 1.6 1 1 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 IncFII_repA PF02387.10 CDI81346.1 - 1.7 7.7 15.6 2.2 7.3 10.8 1.2 1 0 0 1 1 1 0 IncFII RepA protein family GAGA_bind PF06217.7 CDI81346.1 - 2.3 8.1 15.4 3 7.7 10.7 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family CDC45 PF02724.9 CDI81346.1 - 3 5.7 19.2 3.6 5.5 13.3 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF2413 PF10310.4 CDI81346.1 - 3.1 6.5 21.4 3.6 6.2 14.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) DUF2201_N PF13203.1 CDI81346.1 - 3.4 6.7 12.1 4.1 6.4 8.4 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain Rubella_Capsid PF05750.6 CDI81346.1 - 6 6.1 6.9 7.8 5.7 4.8 1.2 1 0 0 1 1 1 0 Rubella capsid protein DUF1168 PF06658.7 CDI81346.1 - 7.5 6.0 36.9 1.3 8.5 22.4 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1168) Herpes_DNAp_acc PF04929.7 CDI81346.1 - 7.9 5.3 18.2 10 4.9 12.6 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Apt1 PF10351.4 CDI81346.1 - 9.4 4.9 18.5 10 4.8 12.8 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF4125 PF13526.1 CDI81348.1 - 0.14 11.6 0.0 1.9 7.9 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4125) Lipase_3 PF01764.20 CDI81349.1 - 9.9e-12 44.6 0.0 1.8e-11 43.8 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Voldacs PF03517.8 CDI81350.1 - 5.4e-23 81.3 0.6 3.7e-22 78.6 0.5 2.1 2 1 0 2 2 2 1 Regulator of volume decrease after cellular swelling DUF1448 PF07289.6 CDI81350.1 - 0.01 14.7 0.0 0.011 14.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1448) Coatomer_WDAD PF04053.9 CDI81352.1 - 8.3e-07 28.1 0.4 0.0021 16.9 0.1 3.4 3 0 0 3 3 3 2 Coatomer WD associated region PPR PF01535.15 CDI81352.1 - 0.16 12.0 0.1 50 4.1 0.0 4.2 4 0 0 4 4 4 0 PPR repeat ubiquitin PF00240.18 CDI81354.1 - 0.00025 20.3 0.0 0.00052 19.3 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family DUF4131 PF13567.1 CDI81354.1 - 0.081 12.3 2.9 0.14 11.6 2.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) AhpC-TSA PF00578.16 CDI81357.1 - 1.8e-30 105.1 0.0 2.2e-30 104.8 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 CDI81357.1 - 3.3e-12 46.1 0.0 4.1e-12 45.8 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.4 CDI81357.1 - 7.1e-10 38.3 0.2 1.4e-09 37.4 0.0 1.6 2 0 0 2 2 2 1 C-terminal domain of 1-Cys peroxiredoxin AhpC-TSA_2 PF13911.1 CDI81357.1 - 0.0033 17.3 0.0 0.0045 16.8 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme GSHPx PF00255.14 CDI81357.1 - 0.086 12.2 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 Glutathione peroxidase CDK5_activator PF03261.10 CDI81358.1 - 0.076 12.3 0.4 7.4 5.8 0.0 2.2 2 0 0 2 2 2 0 Cyclin-dependent kinase 5 activator protein SET PF00856.23 CDI81359.1 - 2.1e-05 24.8 0.3 0.00067 20.0 0.2 2.4 2 0 0 2 2 2 1 SET domain ADK PF00406.17 CDI81360.1 - 1.5e-30 106.0 0.0 6.3e-20 71.5 0.0 2.0 2 0 0 2 2 2 2 Adenylate kinase AAA_17 PF13207.1 CDI81360.1 - 3.3e-09 37.5 0.0 8e-09 36.3 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 CDI81360.1 - 1.8e-05 24.6 0.0 0.00028 20.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 CDI81360.1 - 0.00039 20.7 0.4 0.0018 18.5 0.0 2.2 2 1 0 2 2 2 1 AAA domain ADK_lid PF05191.9 CDI81360.1 - 0.01 15.4 1.6 0.051 13.2 1.1 2.1 1 1 0 1 1 1 0 Adenylate kinase, active site lid AAA PF00004.24 CDI81360.1 - 0.032 14.4 0.0 0.065 13.4 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.17 CDI81360.1 - 0.048 13.8 0.0 8.8 6.5 0.0 2.4 2 0 0 2 2 2 0 RNA helicase SKI PF01202.17 CDI81360.1 - 0.12 12.2 0.0 0.3 10.9 0.0 1.7 1 0 0 1 1 1 0 Shikimate kinase NACHT PF05729.7 CDI81360.1 - 0.14 11.8 0.3 12 5.5 0.0 2.3 2 0 0 2 2 2 0 NACHT domain Ribosomal_60s PF00428.14 CDI81361.1 - 1.1 9.7 7.0 0.28 11.5 0.5 2.6 2 0 0 2 2 2 0 60s Acidic ribosomal protein PDEase_I PF00233.14 CDI81363.1 - 2e-45 155.3 0.1 1.9e-43 148.9 0.0 2.7 2 1 1 3 3 3 2 3'5'-cyclic nucleotide phosphodiesterase Dot_icm_IcmQ PF09475.5 CDI81363.1 - 0.17 11.0 0.8 0.32 10.1 0.6 1.3 1 0 0 1 1 1 0 Dot/Icm secretion system protein (dot_icm_IcmQ) Sporozoite_P67 PF05642.6 CDI81371.1 - 0.19 9.5 18.7 0.24 9.2 13.0 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Hid1 PF12722.2 CDI81371.1 - 1.2 6.7 4.1 1.4 6.5 2.8 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein PHD_3 PF13922.1 CDI81371.1 - 1.9 8.7 8.3 6.3 7.1 5.8 2.0 1 0 0 1 1 1 0 PHD domain of transcriptional enhancer, Asx RskA PF10099.4 CDI81372.1 - 0.0053 16.5 4.5 0.0069 16.1 3.1 1.2 1 0 0 1 1 1 1 Anti-sigma-K factor rskA SR-25 PF10500.4 CDI81372.1 - 0.014 14.8 0.9 0.015 14.7 0.6 1.0 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein VIT1 PF01988.14 CDI81372.1 - 0.033 13.6 2.1 0.038 13.4 1.4 1.1 1 0 0 1 1 1 0 VIT family CST-I PF06002.7 CDI81372.1 - 0.033 13.4 0.0 0.038 13.2 0.0 1.1 1 0 0 1 1 1 0 Alpha-2,3-sialyltransferase (CST-I) K_channel_TID PF07941.6 CDI81372.1 - 0.04 14.1 1.9 0.04 14.1 1.3 1.9 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain Glt_symporter PF03616.9 CDI81372.1 - 0.049 12.1 0.7 0.053 11.9 0.5 1.0 1 0 0 1 1 1 0 Sodium/glutamate symporter AAA_23 PF13476.1 CDI81372.1 - 0.38 11.0 6.9 0.44 10.8 4.8 1.2 1 0 0 1 1 1 0 AAA domain FLO_LFY PF01698.11 CDI81372.1 - 1 8.1 7.7 1.1 8.0 5.3 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein OATP PF03137.15 CDI81372.1 - 2.4 6.1 4.4 2.5 6.0 3.0 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Med13_N PF11597.3 CDI81372.1 - 7.2 5.1 10.6 8.3 4.9 7.4 1.1 1 0 0 1 1 1 0 Mediator complex subunit 13 N-terminal DUF912 PF06024.7 CDI81373.1 - 0.0036 17.3 0.1 0.0036 17.3 0.1 9.0 9 2 0 9 9 9 1 Nucleopolyhedrovirus protein of unknown function (DUF912) Toprim_2 PF13155.1 CDI81377.1 - 0.068 13.5 0.7 0.068 13.5 0.5 2.5 2 0 0 2 2 2 0 Toprim-like T2SF PF00482.18 CDI81377.1 - 3.9 7.3 6.6 3.2 7.6 0.3 3.1 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein F CDC27 PF09507.5 CDI81377.1 - 4 6.5 60.7 1.5 7.9 31.2 2.2 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 Activator_LAG-3 PF11498.3 CDI81381.1 - 0.00047 19.0 65.4 0.00047 19.0 45.4 6.7 5 1 1 6 6 6 3 Transcriptional activator LAG-3 Tyrosinase PF00264.15 CDI81383.1 - 0.88 9.6 10.6 0.97 9.5 7.3 1.0 1 0 0 1 1 1 0 Common central domain of tyrosinase DUF1510 PF07423.6 CDI81383.1 - 1.2 8.5 26.9 1.5 8.1 18.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Serinc PF03348.10 CDI81383.1 - 6.2 5.4 17.1 7.3 5.1 11.8 1.3 1 0 0 1 1 1 0 Serine incorporator (Serinc) Pal1 PF08316.6 CDI81383.1 - 8.3 6.8 16.7 9.8 6.6 11.6 1.0 1 0 0 1 1 1 0 Pal1 cell morphology protein DUF2052 PF09747.4 CDI81383.1 - 9.7 6.0 29.9 11 5.9 20.7 1.1 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) SpoVR PF04293.8 CDI81383.1 - 9.8 4.4 20.8 11 4.2 14.4 1.0 1 0 0 1 1 1 0 SpoVR like protein IncA PF04156.9 CDI81392.1 - 4.2e-05 23.2 23.4 5.4e-05 22.8 16.2 1.1 1 0 0 1 1 1 1 IncA protein UPF0564 PF10595.4 CDI81392.1 - 0.014 14.2 37.8 0.015 14.2 26.2 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0564 FLO_LFY PF01698.11 CDI81392.1 - 0.017 14.0 21.7 0.019 13.8 15.0 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein Shadoo PF14999.1 CDI81392.1 - 0.03 14.1 3.0 0.038 13.8 2.1 1.2 1 0 0 1 1 1 0 Shadow of prion protein, neuroprotective CAF-1_p150 PF11600.3 CDI81392.1 - 0.039 13.3 34.3 0.045 13.1 23.8 1.0 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF4175 PF13779.1 CDI81392.1 - 0.041 11.5 52.7 0.048 11.3 36.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) MIP-T3 PF10243.4 CDI81392.1 - 0.067 11.6 33.8 0.08 11.3 23.4 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 U79_P34 PF03064.11 CDI81392.1 - 0.11 12.0 24.0 0.13 11.7 16.6 1.0 1 0 0 1 1 1 0 HSV U79 / HCMV P34 DUF4220 PF13968.1 CDI81392.1 - 0.12 11.4 11.7 0.13 11.3 8.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4220) DDHD PF02862.12 CDI81392.1 - 0.13 11.9 21.6 0.16 11.7 15.0 1.1 1 0 0 1 1 1 0 DDHD domain Zip PF02535.17 CDI81392.1 - 0.14 11.0 8.2 0.17 10.8 5.6 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter DUF1510 PF07423.6 CDI81392.1 - 0.17 11.2 26.4 0.19 11.0 18.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Vfa1 PF08432.5 CDI81392.1 - 0.2 11.6 28.2 0.23 11.4 19.6 1.0 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Pox_Ag35 PF03286.9 CDI81392.1 - 0.2 11.1 16.2 0.25 10.8 11.2 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Med15 PF09606.5 CDI81392.1 - 0.25 9.5 63.9 0.3 9.2 44.3 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal BTV_NS2 PF04514.7 CDI81392.1 - 0.25 10.1 22.3 0.31 9.8 15.5 1.0 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Gag_spuma PF03276.9 CDI81392.1 - 0.3 9.3 40.3 0.37 9.0 27.9 1.2 1 0 0 1 1 1 0 Spumavirus gag protein SprA-related PF12118.3 CDI81392.1 - 0.34 10.1 53.0 0.54 9.5 36.7 1.3 1 0 0 1 1 1 0 SprA-related family Ycf1 PF05758.7 CDI81392.1 - 0.39 8.3 23.1 0.41 8.3 16.0 1.0 1 0 0 1 1 1 0 Ycf1 AUX_IAA PF02309.11 CDI81392.1 - 0.39 10.4 19.1 0.44 10.2 13.3 1.1 1 0 0 1 1 1 0 AUX/IAA family HemX PF04375.9 CDI81392.1 - 0.44 9.0 40.1 0.51 8.8 27.8 1.0 1 0 0 1 1 1 0 HemX Dsh_C PF12316.3 CDI81392.1 - 0.45 10.5 10.6 0.48 10.4 7.3 1.1 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal FAM60A PF15396.1 CDI81392.1 - 0.45 10.2 22.5 0.54 9.9 15.6 1.0 1 0 0 1 1 1 0 Protein Family FAM60A SR-25 PF10500.4 CDI81392.1 - 0.59 9.5 26.3 0.87 9.0 18.3 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF2217 PF10265.4 CDI81392.1 - 0.6 8.8 12.6 0.74 8.5 8.8 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) PAT1 PF09770.4 CDI81392.1 - 0.6 8.2 49.7 0.62 8.2 34.5 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 FAM91_C PF14648.1 CDI81392.1 - 0.69 8.6 8.5 0.68 8.7 5.9 1.1 1 0 0 1 1 1 0 FAM91 C-terminus PPP4R2 PF09184.6 CDI81392.1 - 0.8 9.1 15.5 0.9 9.0 10.8 1.1 1 0 0 1 1 1 0 PPP4R2 SOBP PF15279.1 CDI81392.1 - 1 9.7 21.9 1.1 9.5 15.1 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein DUF3450 PF11932.3 CDI81392.1 - 1 8.5 43.7 1.3 8.2 30.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) SAGA-Tad1 PF12767.2 CDI81392.1 - 1 8.9 26.8 1.2 8.7 18.6 1.1 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit Raftlin PF15250.1 CDI81392.1 - 1.1 7.7 22.8 1.2 7.5 15.8 1.0 1 0 0 1 1 1 0 Raftlin GAGA_bind PF06217.7 CDI81392.1 - 1.1 9.1 22.7 1.4 8.8 15.8 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family RR_TM4-6 PF06459.7 CDI81392.1 - 1.3 8.8 25.7 1.5 8.6 17.8 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Pilt PF15453.1 CDI81392.1 - 1.3 8.6 23.4 1.5 8.4 16.2 1.0 1 0 0 1 1 1 0 Protein incorporated later into Tight Junctions Herpes_UL95 PF03038.9 CDI81392.1 - 1.3 7.7 12.3 1.4 7.6 8.5 1.1 1 0 0 1 1 1 0 UL95 family CDC45 PF02724.9 CDI81392.1 - 1.3 6.9 26.8 1.6 6.6 18.5 1.0 1 0 0 1 1 1 0 CDC45-like protein DUF2126 PF09899.4 CDI81392.1 - 1.8 6.5 14.3 2 6.3 9.9 1.3 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) LicD PF04991.8 CDI81392.1 - 1.8 8.6 5.9 1.9 8.5 4.1 1.1 1 0 0 1 1 1 0 LicD family AAA_23 PF13476.1 CDI81392.1 - 1.9 8.7 27.1 2.4 8.4 18.8 1.3 1 0 0 1 1 1 0 AAA domain CKAP2_C PF15297.1 CDI81392.1 - 1.9 7.1 24.7 2.4 6.8 17.1 1.1 1 0 0 1 1 1 0 Cytoskeleton-associated protein 2 C-terminus SID-1_RNA_chan PF13965.1 CDI81392.1 - 2.1 6.4 13.4 2.3 6.2 9.3 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Hamartin PF04388.7 CDI81392.1 - 2.1 6.9 15.8 2.3 6.7 10.9 1.1 1 0 0 1 1 1 0 Hamartin protein Corona_nucleoca PF00937.13 CDI81392.1 - 2.1 7.1 27.7 2.6 6.9 19.2 1.1 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein DUF4045 PF13254.1 CDI81392.1 - 2.6 7.2 22.5 3 7.0 15.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Parvo_coat PF00740.13 CDI81392.1 - 3 6.6 25.2 3.4 6.5 17.5 1.0 1 0 0 1 1 1 0 Parvovirus coat protein VP2 YABBY PF04690.8 CDI81392.1 - 3.4 7.9 14.3 4 7.6 9.9 1.3 1 0 0 1 1 1 0 YABBY protein Gastrin PF00918.12 CDI81392.1 - 3.7 8.3 30.0 4.9 7.9 20.8 1.2 1 0 0 1 1 1 0 Gastrin/cholecystokinin family MRP-S31 PF15433.1 CDI81392.1 - 3.7 6.8 28.3 4.5 6.6 19.6 1.1 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 Cellulose_synt PF03552.9 CDI81392.1 - 3.9 5.6 12.4 4.2 5.5 8.6 1.1 1 0 0 1 1 1 0 Cellulose synthase Presenilin PF01080.12 CDI81392.1 - 3.9 6.1 18.8 4.5 6.0 13.0 1.0 1 0 0 1 1 1 0 Presenilin Neur_chan_memb PF02932.11 CDI81392.1 - 4.1 7.2 17.9 4.8 7.0 12.4 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Asp-B-Hydro_N PF05279.6 CDI81392.1 - 4.3 7.1 20.9 5 6.9 14.5 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region DUF2215 PF10225.4 CDI81392.1 - 4.3 6.7 14.4 5.3 6.4 10.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) DUF4446 PF14584.1 CDI81392.1 - 4.4 7.1 13.0 5.9 6.6 9.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) TFIIA PF03153.8 CDI81392.1 - 4.9 6.9 42.9 5.9 6.6 29.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RNA_pol_Rpb1_5 PF04998.12 CDI81392.1 - 5.8 6.0 16.4 6.7 5.8 11.4 1.0 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 DUF913 PF06025.7 CDI81392.1 - 5.8 5.5 15.2 7.1 5.2 10.6 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) CRT10 PF08728.5 CDI81392.1 - 6.1 4.7 12.4 6.1 4.6 8.6 1.0 1 0 0 1 1 1 0 CRT10 DUF2052 PF09747.4 CDI81392.1 - 6.4 6.6 30.5 7.8 6.3 21.1 1.1 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) DUF2146 PF10220.4 CDI81392.1 - 6.8 4.5 22.1 7.7 4.3 15.3 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2146) Herpes_DNAp_acc PF04929.7 CDI81392.1 - 8 5.3 21.2 9.5 5.0 14.7 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor AvrE PF11725.3 CDI81392.1 - 9 3.1 26.0 9.4 3.0 18.0 1.0 1 0 0 1 1 1 0 Pathogenicity factor MMR1 PF08505.5 CDI81392.1 - 9.4 6.1 30.3 14 5.6 21.0 1.2 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein Peptidase_S64 PF08192.6 CDI81392.1 - 9.6 4.3 18.0 11 4.2 12.5 1.0 1 0 0 1 1 1 0 Peptidase family S64 Filo_glycop PF01611.11 CDI81392.1 - 9.7 4.8 15.0 10 4.7 10.4 1.1 1 0 0 1 1 1 0 Filovirus glycoprotein AAA_11 PF13086.1 CDI81392.1 - 9.7 5.6 24.2 11 5.4 16.8 1.2 1 0 0 1 1 1 0 AAA domain Apt1 PF10351.4 CDI81392.1 - 9.9 4.8 19.6 12 4.6 13.6 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF2040 PF09745.4 CDI81394.1 - 8.3e-07 28.8 34.1 0.00056 19.7 11.6 3.7 3 1 0 3 3 3 2 Coiled-coil domain-containing protein 55 (DUF2040) Gly-zipper_OmpA PF13436.1 CDI81394.1 - 0.028 14.0 40.6 0.03 13.9 11.4 3.5 3 0 0 3 3 3 0 Glycine-zipper containing OmpA-like membrane domain Sporozoite_P67 PF05642.6 CDI81394.1 - 0.14 9.9 23.6 2.3 5.9 16.4 2.2 1 1 0 1 1 1 0 Sporozoite P67 surface antigen PAT1 PF09770.4 CDI81394.1 - 0.63 8.2 37.9 0.79 7.8 26.3 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Pyr_redox_2 PF07992.9 CDI81394.1 - 2.6 7.8 9.3 1.3 8.8 1.7 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase RAP1 PF07218.6 CDI81394.1 - 3 5.8 33.3 2.5 6.0 2.1 2.1 2 0 0 2 2 2 0 Rhoptry-associated protein 1 (RAP-1) EF-hand_7 PF13499.1 CDI81407.1 - 8.3e-08 32.2 0.1 1.7e-07 31.2 0.1 1.5 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 CDI81407.1 - 1.9e-05 24.1 0.1 0.21 11.5 0.1 2.7 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.27 CDI81407.1 - 3.2e-05 22.9 0.0 0.0055 15.9 0.1 2.4 2 0 0 2 2 2 1 EF hand BAF1_ABF1 PF04684.8 CDI81407.1 - 6.2e-05 22.0 13.4 6.2e-05 22.0 9.3 6.7 6 1 0 7 7 7 2 BAF1 / ABF1 chromatin reorganising factor EF-hand_8 PF13833.1 CDI81407.1 - 0.0002 20.8 0.3 0.011 15.3 0.1 2.5 2 0 0 2 2 2 1 EF-hand domain pair SR-25 PF10500.4 CDI81407.1 - 0.0012 18.4 49.0 0.0061 16.0 5.1 4.5 4 0 0 4 4 4 3 Nuclear RNA-splicing-associated protein FCP1_C PF09309.5 CDI81407.1 - 0.0057 16.0 3.7 0.0057 16.0 2.6 5.9 5 1 0 6 6 6 2 FCP1, C-terminal YppG PF14179.1 CDI81407.1 - 0.024 15.2 2.5 0.024 15.2 1.8 5.7 5 1 0 5 5 5 0 YppG-like protein Auxin_repressed PF05564.7 CDI81407.1 - 1.2 9.7 10.2 1.1 9.8 0.0 3.4 2 1 1 3 3 3 0 Dormancy/auxin associated protein SR-25 PF10500.4 CDI81408.1 - 0.00072 19.0 2.6 0.00072 19.0 1.8 2.9 3 0 0 3 3 3 2 Nuclear RNA-splicing-associated protein DUF4207 PF13904.1 CDI81408.1 - 0.0099 15.2 4.8 0.0099 15.2 3.3 3.3 3 0 0 3 3 3 1 Domain of unknown function (DUF4207) FimP PF09766.4 CDI81408.1 - 0.016 14.3 19.7 0.093 11.7 1.3 3.2 3 0 0 3 3 3 0 Fms-interacting protein Spt20 PF12090.3 CDI81408.1 - 0.058 12.7 13.5 1.2 8.4 0.9 3.2 3 0 0 3 3 3 0 Spt20 family AAA_23 PF13476.1 CDI81408.1 - 0.12 12.6 16.5 1.9 8.7 5.1 3.1 3 0 0 3 3 3 0 AAA domain SAPS PF04499.10 CDI81408.1 - 2.3 6.7 9.6 0.93 8.0 4.1 2.1 2 1 0 2 2 2 0 SIT4 phosphatase-associated protein DUF3881 PF12997.2 CDI81408.1 - 4.3 6.2 6.3 7.1 5.5 0.1 2.8 3 0 0 3 3 3 0 Domain of unknown function, E. rectale Gene description (DUF3881) DUF3638 PF12340.3 CDI81411.1 - 4e-07 29.2 0.0 8.1e-07 28.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3638) Pex14_N PF04695.8 CDI81411.1 - 0.013 15.5 10.4 0.67 9.9 1.9 2.5 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region ResIII PF04851.10 CDI81411.1 - 0.051 13.4 0.4 0.45 10.3 0.0 2.2 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit APC_CDC26 PF10471.4 CDI81411.1 - 0.69 10.6 11.3 0.32 11.7 1.5 2.5 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit 1 Herpes_pp85 PF04637.7 CDI81411.1 - 4.3 5.5 10.2 0.22 9.7 3.1 1.6 2 0 0 2 2 2 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) Macoilin PF09726.4 CDI81411.1 - 8.1 4.5 17.3 8.9 4.4 8.7 2.0 2 0 0 2 2 2 0 Transmembrane protein SEFIR PF08357.6 CDI81416.1 - 2.8 7.9 10.2 1.2 9.1 1.6 2.8 3 0 0 3 3 3 0 SEFIR domain BAF1_ABF1 PF04684.8 CDI81436.1 - 0.00072 18.5 15.3 0.00072 18.5 10.6 2.9 1 1 2 3 3 2 1 BAF1 / ABF1 chromatin reorganising factor FimP PF09766.4 CDI81436.1 - 0.0016 17.6 28.6 0.023 13.7 4.5 2.2 2 0 0 2 2 2 2 Fms-interacting protein IncA PF04156.9 CDI81436.1 - 0.0054 16.3 3.9 0.0054 16.3 2.7 2.4 2 1 0 2 2 1 1 IncA protein OmpH PF03938.9 CDI81436.1 - 0.018 14.9 8.8 0.018 14.9 6.1 2.4 2 1 0 2 2 1 0 Outer membrane protein (OmpH-like) PAT1 PF09770.4 CDI81436.1 - 0.079 11.2 39.8 0.085 11.0 27.6 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 zf-DHHC PF01529.15 CDI81436.1 - 0.092 12.1 6.6 1.6 8.0 0.9 2.1 2 0 0 2 2 2 0 DHHC palmitoyltransferase Hamartin PF04388.7 CDI81436.1 - 0.36 9.4 20.3 0.28 9.7 13.3 1.2 1 1 0 1 1 1 0 Hamartin protein FHIPEP PF00771.15 CDI81436.1 - 1.2 7.3 15.4 0.95 7.7 4.2 2.1 2 0 0 2 2 2 0 FHIPEP family DUF4207 PF13904.1 CDI81436.1 - 1.5 8.0 38.1 1.7 7.9 6.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4207) CD20 PF04103.10 CDI81436.1 - 4.4 7.2 7.0 1.6 8.6 0.1 2.2 2 0 0 2 2 2 0 CD20-like family Serinc PF03348.10 CDI81436.1 - 5.3 5.6 19.6 1.7 7.2 1.7 2.1 2 0 0 2 2 2 0 Serine incorporator (Serinc) PEX11 PF05648.9 CDI81436.1 - 7.4 5.7 9.2 4.9 6.3 1.3 2.2 2 0 0 2 2 2 0 Peroxisomal biogenesis factor 11 (PEX11) Baculo_PP31 PF05311.6 CDI81436.1 - 7.7 5.6 18.3 1.5 8.0 1.0 2.3 2 0 0 2 2 2 0 Baculovirus 33KDa late protein (PP31) UPF0560 PF10577.4 CDI81436.1 - 9.7 4.3 31.1 2.6 6.1 4.8 2.2 2 0 0 2 2 2 0 Uncharacterised protein family UPF0560 POPLD PF08170.7 CDI81443.1 - 9.6e-06 25.3 0.0 9.6e-06 25.3 0.0 5.3 4 1 1 5 5 5 1 POPLD (NUC188) domain CDK2AP PF09806.4 CDI81443.1 - 0.0054 16.9 4.9 0.0054 16.9 3.4 9.4 5 3 2 7 7 7 1 Cyclin-dependent kinase 2-associated protein Ribosomal_60s PF00428.14 CDI81450.1 - 0.0083 16.5 4.9 0.013 15.8 3.4 1.3 1 0 0 1 1 1 1 60s Acidic ribosomal protein BAF1_ABF1 PF04684.8 CDI81450.1 - 0.0096 14.8 13.8 0.013 14.3 9.6 1.2 1 0 0 1 1 1 1 BAF1 / ABF1 chromatin reorganising factor Chorion_2 PF03964.10 CDI81450.1 - 0.015 15.7 1.4 0.026 15.0 1.0 1.4 1 0 0 1 1 1 0 Chorion family 2 Med15 PF09606.5 CDI81450.1 - 0.14 10.2 17.6 0.15 10.2 12.2 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal FliD_N PF02465.13 CDI81450.1 - 0.26 11.6 7.4 0.37 11.1 5.1 1.2 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 N-terminus DUF429 PF04250.8 CDI81450.1 - 1.4 8.1 5.8 1.9 7.7 4.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF429) Macoilin PF09726.4 CDI81450.1 - 2.6 6.2 15.0 3.2 5.9 10.4 1.0 1 0 0 1 1 1 0 Transmembrane protein DUF788 PF05620.6 CDI81450.1 - 3.6 7.4 6.2 3.6 7.4 1.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF788) RCC1 PF00415.13 CDI81451.1 - 8.7e-09 35.4 0.1 0.0028 17.8 0.0 4.5 4 0 0 4 4 4 3 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 CDI81451.1 - 1.3e-06 27.8 11.5 3.4e-05 23.3 0.1 4.7 4 0 0 4 4 4 2 Regulator of chromosome condensation (RCC1) repeat RNA_pol_Rpb1_5 PF04998.12 CDI81451.1 - 6.2 5.9 13.7 1.4e+02 1.5 0.0 2.0 2 0 0 2 2 2 0 RNA polymerase Rpb1, domain 5 Peptidase_C2 PF00648.16 CDI81453.1 - 1e-05 24.7 0.0 2e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Calpain family cysteine protease zf-DHHC PF01529.15 CDI81453.1 - 0.25 10.7 7.0 2 7.7 0.0 3.5 5 0 0 5 5 5 0 DHHC palmitoyltransferase LRR_6 PF13516.1 CDI81454.1 - 0.00096 18.9 11.3 1.1 9.5 0.1 6.7 7 0 0 7 7 7 2 Leucine Rich repeat LRR_4 PF12799.2 CDI81454.1 - 0.0011 18.5 5.8 0.0087 15.6 0.1 3.9 3 2 1 5 5 5 2 Leucine Rich repeats (2 copies) Spt20 PF12090.3 CDI81457.1 - 0.00011 21.6 15.4 0.05 12.9 0.3 3.1 3 0 0 3 3 3 3 Spt20 family DUF4414 PF14377.1 CDI81457.1 - 0.028 14.3 0.4 0.028 14.3 0.3 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4414) Neur_chan_memb PF02932.11 CDI81457.1 - 0.067 13.0 8.0 0.28 11.0 2.1 2.2 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region DUF3371 PF11851.3 CDI81457.1 - 0.49 11.0 22.5 0.88 10.2 0.9 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF3371) DUF775 PF05603.7 CDI81457.1 - 2.2 7.7 20.7 0.15 11.5 0.3 3.5 4 0 0 4 4 4 0 Protein of unknown function (DUF775) Activator_LAG-3 PF11498.3 CDI81457.1 - 3.3 6.3 57.7 0.1 11.3 4.3 3.1 3 0 0 3 3 3 0 Transcriptional activator LAG-3 DUF1043 PF06295.7 CDI81457.1 - 3.5 7.2 18.0 0.28 10.8 0.3 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1043) SPX PF03105.14 CDI81457.1 - 7 6.3 10.4 30 4.2 7.2 1.9 1 1 0 1 1 1 0 SPX domain RAP1 PF07218.6 CDI81459.1 - 0.33 9.0 5.5 0.31 9.0 3.8 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DDHD PF02862.12 CDI81459.1 - 0.37 10.5 8.6 0.45 10.2 6.0 1.3 1 0 0 1 1 1 0 DDHD domain CAF-1_p150 PF11600.3 CDI81459.1 - 0.44 9.8 19.5 0.026 13.8 9.7 1.6 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal PmbA_TldD PF01523.11 CDI81459.1 - 1.6 7.9 5.3 2 7.6 3.7 1.1 1 0 0 1 1 1 0 Putative modulator of DNA gyrase PBP_sp32 PF07222.7 CDI81459.1 - 3.5 6.7 15.8 5.6 6.0 10.9 1.2 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Corona_nucleoca PF00937.13 CDI81459.1 - 5.7 5.7 21.2 7.1 5.4 14.6 1.3 1 1 0 1 1 1 0 Coronavirus nucleocapsid protein Golgin_A5 PF09787.4 CDI81459.1 - 6.1 5.2 21.7 8.7 4.7 15.1 1.3 1 1 0 1 1 1 0 Golgin subfamily A member 5 SRP-alpha_N PF04086.8 CDI81459.1 - 6.3 6.0 14.7 0.27 10.5 2.4 2.0 2 0 0 2 2 2 0 Signal recognition particle, alpha subunit, N-terminal DUF4602 PF15375.1 CDI81459.1 - 6.3 6.8 14.5 17 5.4 0.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4602) RAM PF15320.1 CDI81459.1 - 6.4 7.1 11.2 1.3 9.3 4.4 2.0 2 0 0 2 2 2 0 mRNA cap methylation, RNMT-activating mini protein DUF912 PF06024.7 CDI81459.1 - 6.6 6.8 9.0 6 6.9 2.3 2.4 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) TPR_14 PF13428.1 CDI81460.1 - 0.013 16.1 6.1 1.6 9.5 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat Apc3 PF12895.2 CDI81460.1 - 0.029 14.5 1.0 0.077 13.1 0.7 1.8 1 1 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 Ribosomal_60s PF00428.14 CDI81460.1 - 0.14 12.5 6.0 0.25 11.7 4.1 1.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein Chorion_2 PF03964.10 CDI81460.1 - 0.9 10.1 4.8 1.6 9.3 3.3 1.4 1 0 0 1 1 1 0 Chorion family 2 PIRT PF15099.1 CDI81466.1 - 0.013 14.7 0.4 0.013 14.7 0.3 5.1 5 0 0 5 5 5 0 Phosphoinositide-interacting protein family DUF3995 PF13160.1 CDI81466.1 - 3.1 7.8 10.6 0.98 9.4 1.8 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3995) Ribosomal_60s PF00428.14 CDI81470.1 - 0.021 15.2 27.4 0.039 14.3 4.5 2.4 2 0 0 2 2 2 0 60s Acidic ribosomal protein Shadoo PF14999.1 CDI81470.1 - 0.14 12.0 14.4 0.44 10.3 1.0 2.2 2 0 0 2 2 2 0 Shadow of prion protein, neuroprotective CAF-1_p150 PF11600.3 CDI81472.1 - 0.00013 21.4 19.9 0.00013 21.4 13.8 5.2 4 1 1 5 5 5 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal SR-25 PF10500.4 CDI81472.1 - 0.0015 18.0 6.8 0.0015 18.0 4.7 6.0 4 1 1 5 5 5 2 Nuclear RNA-splicing-associated protein DUF4179 PF13786.1 CDI81472.1 - 1.5 9.0 8.4 2.3 8.5 0.3 3.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4179) DUF2899 PF11449.3 CDI81472.1 - 7.7 5.6 16.8 0.02 14.0 1.1 3.6 2 1 1 3 3 3 0 Protein of unknown function (DUF2899) BCCT PF02028.12 CDI81491.1 - 0.15 10.2 0.8 9.2 4.3 0.2 2.2 2 0 0 2 2 2 0 BCCT family transporter Chordopox_G3 PF06129.7 CDI81491.1 - 0.27 11.3 0.0 0.27 11.3 0.0 4.9 4 1 1 5 5 5 0 Chordopoxvirus G3 protein FAM176 PF14851.1 CDI81491.1 - 0.45 10.1 25.2 0.58 9.8 0.1 5.1 5 0 0 5 5 5 0 FAM176 family Cytochrom_B_N PF00033.14 CDI81491.1 - 4.1 6.7 5.8 0.83 8.9 0.1 2.6 3 0 0 3 3 3 0 Cytochrome b(N-terminal)/b6/petB AP2 PF00847.15 CDI81493.1 - 0.00018 21.5 0.8 0.00018 21.5 0.6 9.2 13 1 0 13 13 13 1 AP2 domain DUF4342 PF14242.1 CDI81494.1 - 0.5 10.1 10.5 0.55 10.0 0.0 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4342) Med15 PF09606.5 CDI81498.1 - 0.00093 17.5 42.7 0.0011 17.3 29.6 1.0 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal DUF677 PF05055.7 CDI81498.1 - 0.0031 16.2 0.7 0.0037 15.9 0.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF677) DUF2721 PF11026.3 CDI81498.1 - 0.0085 15.7 2.0 0.011 15.3 1.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2721) Plasmodium_Vir PF05795.6 CDI81498.1 - 0.039 13.1 16.1 0.051 12.7 11.2 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein DUF4395 PF14340.1 CDI81498.1 - 0.071 13.1 3.5 0.095 12.7 2.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4395) RskA PF10099.4 CDI81498.1 - 0.15 11.7 16.3 0.21 11.3 11.3 1.3 1 0 0 1 1 1 0 Anti-sigma-K factor rskA Na_trans_assoc PF06512.8 CDI81498.1 - 0.23 11.4 23.8 0.29 11.0 16.5 1.1 1 0 0 1 1 1 0 Sodium ion transport-associated Tmemb_cc2 PF10267.4 CDI81498.1 - 0.3 9.6 29.0 0.4 9.2 20.1 1.1 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein DUF1911 PF08929.5 CDI81498.1 - 0.37 11.5 4.7 0.6 10.8 3.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1911) SpaB_C PF14028.1 CDI81498.1 - 0.47 9.9 9.9 0.53 9.7 6.9 1.0 1 0 0 1 1 1 0 SpaB C-terminal domain MAP65_ASE1 PF03999.7 CDI81498.1 - 0.83 8.1 37.1 0.94 8.0 25.7 1.0 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) Macoilin PF09726.4 CDI81498.1 - 1.4 7.1 44.3 1.7 6.8 30.7 1.0 1 0 0 1 1 1 0 Transmembrane protein WES_acyltransf PF03007.11 CDI81498.1 - 2.2 7.7 11.3 2.6 7.5 7.8 1.2 1 0 0 1 1 1 0 Wax ester synthase-like Acyl-CoA acyltransferase domain BAF1_ABF1 PF04684.8 CDI81502.1 - 0.0001 21.3 51.3 0.0001 21.3 35.5 3.7 1 1 3 4 4 1 1 BAF1 / ABF1 chromatin reorganising factor DUF1510 PF07423.6 CDI81502.1 - 0.039 13.3 18.2 0.049 12.9 12.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Plasmodium_Vir PF05795.6 CDI81502.1 - 0.057 12.6 2.1 0.065 12.4 1.5 1.3 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Bul1_N PF04425.7 CDI81502.1 - 0.2 10.1 10.2 0.22 10.0 7.1 1.2 1 0 0 1 1 1 0 Bul1 N terminus Ycf1 PF05758.7 CDI81502.1 - 0.27 8.8 12.8 0.31 8.7 8.9 1.0 1 0 0 1 1 1 0 Ycf1 Raftlin PF15250.1 CDI81502.1 - 0.37 9.2 11.0 0.41 9.1 7.6 1.3 1 0 0 1 1 1 0 Raftlin Pap_E4 PF02711.9 CDI81502.1 - 0.42 11.4 10.1 0.81 10.5 7.0 1.5 1 0 0 1 1 1 0 E4 protein SDA1 PF05285.7 CDI81502.1 - 0.59 9.3 18.8 0.71 9.0 13.0 1.2 1 0 0 1 1 1 0 SDA1 Cellulose_synt PF03552.9 CDI81502.1 - 0.65 8.2 4.5 0.68 8.1 3.1 1.1 1 0 0 1 1 1 0 Cellulose synthase MMR1 PF08505.5 CDI81502.1 - 1.1 9.2 20.5 1.4 8.9 14.2 1.2 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein Dicty_REP PF05086.7 CDI81502.1 - 1.2 6.8 10.7 1.5 6.4 7.4 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF966 PF06136.8 CDI81502.1 - 1.5 8.1 17.5 2 7.7 12.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF966) SAPS PF04499.10 CDI81502.1 - 1.8 7.1 13.5 2.3 6.7 9.4 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein PLRV_ORF5 PF01690.12 CDI81502.1 - 2.1 7.4 22.5 2.4 7.1 15.6 1.0 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein MscS_TM PF12794.2 CDI81502.1 - 2.2 6.8 14.0 0.27 9.7 6.7 1.7 1 1 1 2 2 2 0 Mechanosensitive ion channel inner membrane domain 1 CDC45 PF02724.9 CDI81502.1 - 2.6 5.9 17.3 3 5.7 12.0 1.1 1 0 0 1 1 1 0 CDC45-like protein Macoilin PF09726.4 CDI81502.1 - 6.2 4.9 24.5 7.9 4.6 17.0 1.1 1 0 0 1 1 1 0 Transmembrane protein Daxx PF03344.10 CDI81502.1 - 7.5 4.9 26.4 8.9 4.6 18.3 1.0 1 0 0 1 1 1 0 Daxx Family Asp-B-Hydro_N PF05279.6 CDI81502.1 - 7.6 6.2 22.3 11 5.7 15.4 1.3 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Herpes_LMP2 PF07415.6 CDI81502.1 - 9.3 4.7 6.4 12 4.3 4.5 1.1 1 0 0 1 1 1 0 Gammaherpesvirus latent membrane protein (LMP2) protein SOG2 PF10428.4 CDI81504.1 - 0.11 11.1 11.4 0.16 10.5 7.9 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein Bac_luciferase PF00296.15 CDI81513.1 - 0.016 14.3 0.1 0.016 14.3 0.1 2.1 1 1 1 2 2 2 0 Luciferase-like monooxygenase PBP1_TM PF14812.1 CDI81513.1 - 0.27 11.5 5.7 6.5 7.1 0.0 2.3 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal MOR2-PAG1_N PF14222.1 CDI81513.1 - 3.9 6.0 9.7 5.3 5.5 6.7 1.3 1 0 0 1 1 1 0 Cell morphogenesis N-terminal POX PF07526.6 CDI81513.1 - 6.1 7.0 21.2 1 9.5 1.5 2.2 2 0 0 2 2 2 0 Associated with HOX Peroxin-13_N PF04088.8 CDI81513.1 - 7.5 6.4 9.6 2.7 7.9 0.1 2.2 2 0 0 2 2 2 0 Peroxin 13, N-terminal region DUF1917 PF08939.5 CDI81513.1 - 8.4 6.0 15.7 12 5.5 10.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1917) DUF1510 PF07423.6 CDI81521.1 - 1.8e-06 27.5 9.4 1.9e-06 27.4 6.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) RIC3 PF15361.1 CDI81521.1 - 0.00054 20.2 14.8 0.0006 20.0 10.2 1.1 1 0 0 1 1 1 1 Resistance to inhibitors of cholinesterase homologue 3 DUF4131 PF13567.1 CDI81521.1 - 0.00075 18.9 11.5 0.00091 18.6 8.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4131) YfhO PF09586.5 CDI81521.1 - 0.0021 16.2 13.6 0.0027 15.8 9.4 1.2 1 0 0 1 1 1 1 Bacterial membrane protein YfhO DUF3260 PF11658.3 CDI81521.1 - 0.0026 15.9 15.8 0.0027 15.9 10.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3260) Ycf1 PF05758.7 CDI81521.1 - 0.0037 15.0 14.3 0.0035 15.1 9.9 1.0 1 0 0 1 1 1 1 Ycf1 Pex24p PF06398.6 CDI81521.1 - 0.0081 14.9 1.0 0.013 14.3 0.7 1.4 1 1 0 1 1 1 1 Integral peroxisomal membrane peroxin SID-1_RNA_chan PF13965.1 CDI81521.1 - 0.0086 14.3 7.3 0.0089 14.2 5.1 1.0 1 0 0 1 1 1 1 dsRNA-gated channel SID-1 Neur_chan_memb PF02932.11 CDI81521.1 - 0.01 15.7 7.6 0.01 15.7 5.3 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Folate_carrier PF01770.13 CDI81521.1 - 0.016 13.7 11.4 0.017 13.6 7.9 1.1 1 0 0 1 1 1 0 Reduced folate carrier TRAP_alpha PF03896.11 CDI81521.1 - 0.017 14.1 8.2 0.02 13.8 5.7 1.2 1 1 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Serinc PF03348.10 CDI81521.1 - 0.036 12.7 14.4 0.041 12.6 10.0 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) DUF4512 PF14975.1 CDI81521.1 - 0.04 14.7 10.1 0.054 14.3 7.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4512) Neur PF00064.13 CDI81521.1 - 0.058 11.4 3.3 0.065 11.3 2.3 1.0 1 0 0 1 1 1 0 Neuraminidase Herpes_glycop PF01528.11 CDI81521.1 - 0.062 11.9 4.0 0.069 11.8 2.8 1.3 1 0 0 1 1 1 0 Herpesvirus glycoprotein M DUF3429 PF11911.3 CDI81521.1 - 0.07 13.0 0.7 0.1 12.5 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3429) DUF2561 PF10812.3 CDI81521.1 - 0.076 12.6 3.5 0.085 12.4 2.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2561) Mem_trans PF03547.13 CDI81521.1 - 0.093 11.0 7.5 0.099 10.9 5.2 1.1 1 0 0 1 1 1 0 Membrane transport protein Peptidase_M50B PF13398.1 CDI81521.1 - 0.13 11.6 1.4 0.17 11.2 1.0 1.2 1 0 0 1 1 1 0 Peptidase M50B-like Nucleoside_tran PF01733.13 CDI81521.1 - 0.18 10.9 6.0 0.2 10.8 4.2 1.1 1 0 0 1 1 1 0 Nucleoside transporter K_trans PF02705.11 CDI81521.1 - 0.21 9.9 2.8 0.26 9.6 2.0 1.3 1 0 0 1 1 1 0 K+ potassium transporter PRA1 PF03208.14 CDI81521.1 - 0.29 10.4 1.3 0.4 10.0 0.9 1.4 1 1 0 1 1 1 0 PRA1 family protein Tmp39 PF10271.4 CDI81521.1 - 0.36 9.4 7.2 0.38 9.3 5.0 1.1 1 0 0 1 1 1 0 Putative transmembrane protein Baculo_PP31 PF05311.6 CDI81521.1 - 0.37 9.9 18.1 0.44 9.7 12.5 1.2 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) Sre PF03125.13 CDI81521.1 - 0.64 8.8 3.3 0.7 8.7 2.3 1.0 1 0 0 1 1 1 0 C. elegans Sre G protein-coupled chemoreceptor Stig1 PF04885.8 CDI81521.1 - 0.75 10.0 8.0 1.1 9.4 5.6 1.3 1 0 0 1 1 1 0 Stigma-specific protein, Stig1 TerC PF03741.11 CDI81521.1 - 1.4 8.3 7.4 4.9 6.5 5.1 1.8 1 1 0 1 1 1 0 Integral membrane protein TerC family DUF4010 PF13194.1 CDI81521.1 - 1.4 8.1 8.1 2.2 7.5 5.6 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4010) FHIPEP PF00771.15 CDI81521.1 - 1.9 6.6 19.3 4.2 5.5 13.4 1.5 1 1 0 1 1 1 0 FHIPEP family ALG3 PF05208.8 CDI81521.1 - 2 7.5 10.2 2.3 7.3 7.1 1.2 1 0 0 1 1 1 0 ALG3 protein DUF1980 PF09323.5 CDI81521.1 - 2.2 8.0 19.2 0.43 10.3 11.2 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF1980) FAM91_C PF14648.1 CDI81521.1 - 2.5 6.8 10.5 2.6 6.7 7.3 1.0 1 0 0 1 1 1 0 FAM91 C-terminus DUF4446 PF14584.1 CDI81521.1 - 2.7 7.8 19.4 4.1 7.2 13.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF4446) Dynamin_N PF00350.18 CDI81521.1 - 3.2 7.5 11.0 4.5 7.0 7.7 1.4 1 0 0 1 1 1 0 Dynamin family BORG_CEP PF14957.1 CDI81521.1 - 4.2 8.3 13.8 4.9 8.0 9.5 1.1 1 0 0 1 1 1 0 Cdc42 effector HemY_N PF07219.8 CDI81521.1 - 5.1 6.7 7.9 8.9 5.9 5.5 1.5 1 1 0 1 1 1 0 HemY protein N-terminus RP-C_C PF11800.3 CDI81521.1 - 5.2 6.7 19.3 5.7 6.5 13.3 1.1 1 0 0 1 1 1 0 Replication protein C C-terminal region RBP_receptor PF14752.1 CDI81521.1 - 5.5 5.1 10.7 6.6 4.9 7.4 1.2 1 0 0 1 1 1 0 Retinol binding protein receptor AGTRAP PF06396.6 CDI81521.1 - 5.8 6.5 5.5 6.8 6.3 3.8 1.3 1 0 0 1 1 1 0 Angiotensin II, type I receptor-associated protein (AGTRAP) FAM176 PF14851.1 CDI81521.1 - 6.1 6.5 17.7 10 5.7 12.1 1.6 1 1 0 1 1 1 0 FAM176 family LpxB PF02684.10 CDI81521.1 - 6.1 5.3 14.2 7 5.1 9.8 1.2 1 0 0 1 1 1 0 Lipid-A-disaccharide synthetase Anoctamin PF04547.7 CDI81521.1 - 7.2 5.1 15.4 8.6 4.8 10.7 1.3 1 0 0 1 1 1 0 Calcium-activated chloride channel R_equi_Vir PF05526.6 CDI81521.1 - 8.9 5.9 7.5 12 5.4 5.2 1.3 1 0 0 1 1 1 0 Rhodococcus equi virulence-associated protein Herpes_DNAp_acc PF04929.7 CDI81521.1 - 9.3 5.1 18.9 10 4.9 13.1 1.0 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Med15 PF09606.5 CDI81525.1 - 0.0006 18.1 41.9 0.0006 18.1 29.1 3.1 3 0 0 3 3 3 1 ARC105 or Med15 subunit of Mediator complex non-fungal DUF1510 PF07423.6 CDI81525.1 - 0.0014 18.0 31.5 0.0014 18.0 21.9 3.8 2 2 1 3 3 3 1 Protein of unknown function (DUF1510) Neur_chan_memb PF02932.11 CDI81525.1 - 0.0035 17.2 22.7 0.0035 17.2 15.8 3.2 1 1 1 2 2 2 1 Neurotransmitter-gated ion-channel transmembrane region PIH1 PF08190.7 CDI81527.1 - 1.2e-05 24.9 0.4 0.001 18.5 0.0 8.4 3 2 5 9 9 9 2 pre-RNA processing PIH1/Nop17 Cellulose_synt PF03552.9 CDI81528.1 - 3.1 5.9 14.1 2.3 6.4 2.9 2.3 2 0 0 2 2 2 0 Cellulose synthase Mucin PF01456.12 CDI81530.1 - 1.3e-05 24.9 1.9 1.6e-05 24.7 1.3 1.1 1 0 0 1 1 1 1 Mucin-like glycoprotein SpoIIIAH PF12685.2 CDI81530.1 - 4e-05 23.1 7.5 4.9e-05 22.9 5.2 1.1 1 0 0 1 1 1 1 SpoIIIAH-like protein FAM176 PF14851.1 CDI81530.1 - 8.2e-05 22.3 2.1 9.6e-05 22.1 1.4 1.1 1 0 0 1 1 1 1 FAM176 family DUF2514 PF10721.4 CDI81530.1 - 0.00013 21.6 22.6 0.00018 21.2 15.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2514) Ctr PF04145.10 CDI81530.1 - 0.0056 16.7 5.4 0.0067 16.4 3.7 1.2 1 0 0 1 1 1 1 Ctr copper transporter family Tetraspannin PF00335.15 CDI81530.1 - 0.0058 15.9 1.9 0.006 15.8 1.3 1.2 1 0 0 1 1 1 1 Tetraspanin family RIC3 PF15361.1 CDI81530.1 - 0.0062 16.7 4.5 0.0073 16.5 3.1 1.2 1 0 0 1 1 1 1 Resistance to inhibitors of cholinesterase homologue 3 DUF4446 PF14584.1 CDI81530.1 - 0.0096 15.7 6.9 0.011 15.5 4.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4446) SID-1_RNA_chan PF13965.1 CDI81530.1 - 0.011 13.9 4.7 0.012 13.8 3.3 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DUF3357 PF11837.3 CDI81530.1 - 0.014 15.2 4.9 0.015 15.1 0.7 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF3357) TRAP_alpha PF03896.11 CDI81530.1 - 0.014 14.4 1.6 0.015 14.3 1.1 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Pex16 PF08610.5 CDI81530.1 - 0.014 14.4 8.1 0.015 14.2 5.6 1.0 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) TMEM51 PF15345.1 CDI81530.1 - 0.017 14.7 17.9 0.038 13.6 12.4 1.6 1 1 0 1 1 1 0 Transmembrane protein 51 BAF1_ABF1 PF04684.8 CDI81530.1 - 0.017 13.9 36.4 0.021 13.6 25.2 1.0 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor V_ATPase_I PF01496.14 CDI81530.1 - 0.019 12.8 1.6 0.019 12.8 1.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF3007 PF11460.3 CDI81530.1 - 0.022 14.8 5.5 0.034 14.2 3.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3007) YfhO PF09586.5 CDI81530.1 - 0.029 12.4 5.8 0.03 12.3 4.0 1.1 1 0 0 1 1 1 0 Bacterial membrane protein YfhO SDF PF00375.13 CDI81530.1 - 0.031 13.0 1.8 0.035 12.8 1.3 1.1 1 0 0 1 1 1 0 Sodium:dicarboxylate symporter family ABC2_membrane_2 PF12679.2 CDI81530.1 - 0.032 13.0 3.9 0.039 12.7 2.7 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF4512 PF14975.1 CDI81530.1 - 0.037 14.8 0.7 0.054 14.3 0.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4512) Cytochrom_B_N PF00033.14 CDI81530.1 - 0.038 13.3 0.2 0.042 13.2 0.2 1.2 1 0 0 1 1 1 0 Cytochrome b(N-terminal)/b6/petB Endonuc_Holl PF10107.4 CDI81530.1 - 0.045 13.4 8.4 0.052 13.2 5.8 1.3 1 0 0 1 1 1 0 Endonuclease related to archaeal Holliday junction resolvase MLANA PF14991.1 CDI81530.1 - 0.06 13.3 1.0 0.077 13.0 0.6 1.3 1 1 0 1 1 1 0 Protein melan-A Neur_chan_memb PF02932.11 CDI81530.1 - 0.066 13.0 2.6 0.075 12.9 1.8 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region NicO PF03824.11 CDI81530.1 - 0.067 12.4 2.5 0.078 12.2 1.7 1.1 1 0 0 1 1 1 0 High-affinity nickel-transport protein Neur PF00064.13 CDI81530.1 - 0.07 11.2 2.4 0.071 11.1 1.7 1.0 1 0 0 1 1 1 0 Neuraminidase Ycf1 PF05758.7 CDI81530.1 - 0.075 10.7 4.0 0.075 10.7 2.8 1.0 1 0 0 1 1 1 0 Ycf1 OATP PF03137.15 CDI81530.1 - 0.079 10.9 2.0 0.083 10.9 1.4 1.2 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family PIG-P PF08510.7 CDI81530.1 - 0.089 12.4 1.0 0.1 12.2 0.7 1.2 1 1 0 1 1 1 0 PIG-P DUF4386 PF14329.1 CDI81530.1 - 0.11 11.9 3.1 0.78 9.1 0.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4386) HRXXH PF13933.1 CDI81530.1 - 0.14 11.5 8.1 0.17 11.2 5.6 1.1 1 0 0 1 1 1 0 Putative peptidase family Scs3p PF10261.4 CDI81530.1 - 0.16 11.0 1.1 0.19 10.7 0.8 1.2 1 0 0 1 1 1 0 Inositol phospholipid synthesis and fat-storage-inducing TM Spt20 PF12090.3 CDI81530.1 - 0.16 11.2 12.9 0.2 11.0 8.9 1.1 1 0 0 1 1 1 0 Spt20 family OAD_gamma PF04277.8 CDI81530.1 - 0.17 12.3 8.6 0.82 10.0 6.0 1.9 1 1 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain Folate_carrier PF01770.13 CDI81530.1 - 0.17 10.3 4.2 0.17 10.3 2.9 1.1 1 0 0 1 1 1 0 Reduced folate carrier tRNA_anti-like PF12869.2 CDI81530.1 - 0.18 11.3 4.2 0.28 10.6 2.9 1.5 1 1 0 1 1 1 0 tRNA_anti-like Otopetrin PF03189.8 CDI81530.1 - 0.22 10.5 5.6 0.23 10.3 3.9 1.1 1 0 0 1 1 1 0 Otopetrin FAM222A PF15258.1 CDI81530.1 - 0.24 10.5 20.6 0.29 10.3 14.3 1.0 1 0 0 1 1 1 0 Protein family of FAM222A Apc15p PF05841.6 CDI81530.1 - 0.25 12.0 15.7 0.3 11.8 10.9 1.1 1 0 0 1 1 1 0 Apc15p protein DUF2232 PF09991.4 CDI81530.1 - 0.26 10.2 7.8 0.3 10.0 5.4 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) 7tm_1 PF00001.16 CDI81530.1 - 0.26 10.3 3.2 0.43 9.6 2.2 1.5 1 1 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) IncA PF04156.9 CDI81530.1 - 0.28 10.7 27.9 0.51 9.9 19.3 1.6 1 1 0 1 1 1 0 IncA protein HN PF00423.14 CDI81530.1 - 0.28 9.4 3.9 0.29 9.3 2.7 1.1 1 0 0 1 1 1 0 Haemagglutinin-neuraminidase EphA2_TM PF14575.1 CDI81530.1 - 0.28 11.5 8.1 0.85 10.0 5.6 2.0 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Peptidase_M56 PF05569.6 CDI81530.1 - 0.3 9.9 3.1 0.38 9.6 2.2 1.2 1 0 0 1 1 1 0 BlaR1 peptidase M56 K_trans PF02705.11 CDI81530.1 - 0.33 9.2 2.8 0.37 9.1 2.0 1.0 1 0 0 1 1 1 0 K+ potassium transporter Cas1_AcylT PF07779.7 CDI81530.1 - 0.33 9.3 2.8 0.33 9.3 1.9 1.1 1 0 0 1 1 1 0 10 TM Acyl Transferase domain found in Cas1p FUN14 PF04930.10 CDI81530.1 - 0.34 11.2 2.9 0.4 10.9 2.0 1.2 1 0 0 1 1 1 0 FUN14 family LpxB PF02684.10 CDI81530.1 - 0.35 9.4 5.0 0.37 9.3 3.4 1.1 1 0 0 1 1 1 0 Lipid-A-disaccharide synthetase Ribosomal_60s PF00428.14 CDI81530.1 - 0.42 11.0 6.3 0.56 10.6 4.3 1.3 1 0 0 1 1 1 0 60s Acidic ribosomal protein FliP PF00813.15 CDI81530.1 - 0.46 10.1 7.1 0.53 9.9 4.9 1.1 1 0 0 1 1 1 0 FliP family Mem_trans PF03547.13 CDI81530.1 - 0.54 8.5 2.6 0.57 8.4 1.8 1.1 1 0 0 1 1 1 0 Membrane transport protein DUF3260 PF11658.3 CDI81530.1 - 0.6 8.1 9.8 0.69 7.9 6.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3260) Herpes_glycop PF01528.11 CDI81530.1 - 0.79 8.3 4.1 0.93 8.1 2.9 1.3 1 1 0 1 1 1 0 Herpesvirus glycoprotein M DUF2140 PF09911.4 CDI81530.1 - 0.84 8.7 8.1 1.5 7.9 5.6 1.6 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2140) UPF0542 PF15086.1 CDI81530.1 - 0.84 9.4 9.0 1 9.1 4.9 1.9 1 1 1 2 2 2 0 Uncharacterised protein family UPF0542 MSC PF09402.5 CDI81530.1 - 0.88 8.2 9.1 1.2 7.8 6.3 1.2 1 0 0 1 1 1 0 Man1-Src1p-C-terminal domain GRP PF07172.6 CDI81530.1 - 0.92 10.0 7.2 1.4 9.4 5.0 1.7 1 1 0 1 1 1 0 Glycine rich protein family DUF3365 PF11845.3 CDI81530.1 - 1.1 9.1 10.8 1.3 8.8 7.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3365) TMEM154 PF15102.1 CDI81530.1 - 1.1 8.9 20.1 0.093 12.4 5.4 2.1 1 1 1 2 2 2 0 TMEM154 protein family FPN1 PF06963.7 CDI81530.1 - 1.1 7.5 6.1 1.2 7.4 4.0 1.3 1 1 0 1 1 1 0 Ferroportin1 (FPN1) Pal1 PF08316.6 CDI81530.1 - 1.2 9.6 7.2 1.3 9.4 5.0 1.1 1 0 0 1 1 1 0 Pal1 cell morphology protein DUF3573 PF12097.3 CDI81530.1 - 1.2 7.6 11.2 1.4 7.4 7.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) Hid1 PF12722.2 CDI81530.1 - 1.3 6.6 11.4 1.5 6.4 7.9 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Hom_end_hint PF05203.11 CDI81530.1 - 1.3 8.6 7.3 1.4 8.5 5.0 1.1 1 0 0 1 1 1 0 Hom_end-associated Hint DUF966 PF06136.8 CDI81530.1 - 1.4 8.2 11.3 1.6 8.0 7.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Gti1_Pac2 PF09729.4 CDI81530.1 - 1.5 8.6 7.0 1.8 8.4 4.9 1.1 1 0 0 1 1 1 0 Gti1/Pac2 family BRF1 PF07741.8 CDI81530.1 - 1.6 9.0 13.6 2.7 8.2 9.4 1.4 1 0 0 1 1 1 0 Brf1-like TBP-binding domain FemAB PF02388.11 CDI81530.1 - 1.8 7.1 12.9 1.9 7.0 8.9 1.0 1 0 0 1 1 1 0 FemAB family ALG3 PF05208.8 CDI81530.1 - 1.8 7.7 5.6 1.8 7.7 3.9 1.1 1 0 0 1 1 1 0 ALG3 protein DUF2368 PF10166.4 CDI81530.1 - 1.8 8.1 16.9 2.2 7.8 11.7 1.2 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2368) Conotoxin PF02950.12 CDI81530.1 - 1.9 9.3 14.1 13 6.6 9.7 2.3 1 1 0 1 1 1 0 Conotoxin ETRAMP PF09716.5 CDI81530.1 - 1.9 8.4 4.7 5.1 7.1 3.2 1.7 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) DUF3347 PF11827.3 CDI81530.1 - 2 8.3 14.5 2.4 8.1 10.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3347) GPCR_chapero_1 PF11904.3 CDI81530.1 - 2.3 7.3 9.9 2.7 7.0 6.9 1.0 1 0 0 1 1 1 0 GPCR-chaperone Band_3_cyto PF07565.8 CDI81530.1 - 2.3 7.6 10.4 2.7 7.4 7.2 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain MAT1 PF06391.8 CDI81530.1 - 2.3 7.7 15.6 2.8 7.4 10.8 1.1 1 0 0 1 1 1 0 CDK-activating kinase assembly factor MAT1 Stig1 PF04885.8 CDI81530.1 - 2.6 8.2 6.9 4 7.6 4.8 1.4 1 1 0 1 1 1 0 Stigma-specific protein, Stig1 Pam17 PF08566.5 CDI81530.1 - 2.6 7.7 8.7 3.2 7.4 6.0 1.1 1 0 0 1 1 1 0 Mitochondrial import protein Pam17 DUF2149 PF09919.4 CDI81530.1 - 2.6 8.1 7.3 2.2 8.4 4.0 1.6 1 1 1 2 2 1 0 Uncharacterized conserved protein (DUF2149) DUF2973 PF11189.3 CDI81530.1 - 3 7.6 8.9 9.4 6.0 6.1 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF2973) OSTbeta PF15048.1 CDI81530.1 - 3.6 7.6 12.7 6.9 6.7 8.8 1.6 1 1 0 1 1 1 0 Organic solute transporter subunit beta protein DUF3138 PF11336.3 CDI81530.1 - 4 5.5 17.4 4.6 5.3 12.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) PsbW PF07123.7 CDI81530.1 - 4.2 7.4 8.6 6 6.9 6.0 1.3 1 0 0 1 1 1 0 Photosystem II reaction centre W protein (PsbW) Bap31 PF05529.7 CDI81530.1 - 4.5 6.6 14.4 9.9 5.5 10.0 1.6 1 1 0 1 1 1 0 B-cell receptor-associated protein 31-like AAA_23 PF13476.1 CDI81530.1 - 5 7.4 10.2 5.1 7.3 7.1 1.2 1 0 0 1 1 1 0 AAA domain DUF4638 PF15472.1 CDI81530.1 - 5 6.6 8.6 5.6 6.4 5.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) FAM60A PF15396.1 CDI81530.1 - 5 6.7 10.2 5.9 6.5 7.1 1.0 1 0 0 1 1 1 0 Protein Family FAM60A DUF2946 PF11162.3 CDI81530.1 - 5.1 7.3 17.0 23 5.2 11.8 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2946) DUF506 PF04720.7 CDI81530.1 - 5.2 6.6 7.9 6.2 6.3 5.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF506) DDRGK PF09756.4 CDI81530.1 - 5.3 6.4 17.0 6.3 6.1 11.8 1.0 1 0 0 1 1 1 0 DDRGK domain Ammonium_transp PF00909.16 CDI81530.1 - 6.2 5.1 6.8 7.3 4.9 1.7 2.0 2 0 0 2 2 2 0 Ammonium Transporter Family Serinc PF03348.10 CDI81530.1 - 6.4 5.3 10.8 7.4 5.1 7.5 1.3 1 1 0 1 1 1 0 Serine incorporator (Serinc) Abhydrolase_9_N PF15420.1 CDI81530.1 - 6.4 6.4 8.4 7.6 6.2 0.4 2.0 1 1 1 2 2 2 0 Alpha/beta-hydrolase family N-terminus MAPEG PF01124.13 CDI81530.1 - 6.7 6.3 9.8 11 5.6 6.8 1.4 1 1 0 1 1 1 0 MAPEG family DDHD PF02862.12 CDI81530.1 - 6.8 6.4 10.4 8.1 6.1 7.2 1.1 1 0 0 1 1 1 0 DDHD domain DUF4131 PF13567.1 CDI81530.1 - 7 6.0 10.4 9.4 5.5 7.2 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4131) Peptidase_C58 PF03543.9 CDI81530.1 - 7.3 6.0 21.5 8.4 5.8 14.9 1.1 1 0 0 1 1 1 0 Yersinia/Haemophilus virulence surface antigen DUF4557 PF15101.1 CDI81530.1 - 7.7 6.2 23.2 10 5.8 16.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) Peptidase_S64 PF08192.6 CDI81530.1 - 8 4.6 11.4 9.6 4.4 7.9 1.0 1 0 0 1 1 1 0 Peptidase family S64 Tmemb_9 PF05434.6 CDI81530.1 - 8.6 6.0 11.0 5.9 6.6 6.4 1.6 1 1 1 2 2 2 0 TMEM9 DUF843 PF05814.6 CDI81530.1 - 9.7 6.0 6.8 20 5.0 4.7 1.6 1 1 0 1 1 1 0 Baculovirus protein of unknown function (DUF843) HemY_N PF07219.8 CDI81530.1 - 9.7 5.7 14.5 20 4.7 10.0 1.7 1 1 0 1 1 1 0 HemY protein N-terminus DEAD PF00270.24 CDI81532.1 - 6.9e-15 54.9 0.0 6.9e-15 54.9 0.0 1.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase ATP-grasp_4 PF13535.1 CDI81532.1 - 0.13 11.9 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 ATP-grasp domain CMS1 PF14617.1 CDI81532.1 - 0.17 10.9 0.4 0.23 10.5 0.3 1.2 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit Shadoo PF14999.1 CDI81532.1 - 7.8 6.3 14.8 2.1 8.1 6.8 2.1 2 0 0 2 2 2 0 Shadow of prion protein, neuroprotective MOZART1 PF12554.3 CDI81538.1 - 2.2e-20 71.8 0.6 3.3e-20 71.2 0.4 1.3 1 0 0 1 1 1 1 Mitotic-spindle organizing gamma-tubulin ring associated PAP2 PF01569.16 CDI81543.1 - 0.00094 18.8 1.5 1 9.0 0.3 2.8 1 1 1 2 2 2 2 PAP2 superfamily Merozoite_SPAM PF07133.6 CDI81545.1 - 1.5 8.7 25.6 1.8 8.3 17.7 1.2 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) AIF-MLS PF14962.1 CDI81545.1 - 6.7 6.3 23.4 7.7 6.1 16.2 1.1 1 0 0 1 1 1 0 Mitochondria Localisation Sequence Mitofilin PF09731.4 CDI81545.1 - 8.5 4.8 20.0 9.3 4.7 13.8 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein YppG PF14179.1 CDI81546.1 - 1.1 9.8 10.6 1.8 9.2 7.4 1.2 1 0 0 1 1 1 0 YppG-like protein DUF1115 PF06544.7 CDI81550.1 - 0.068 12.8 6.6 0.09 12.4 4.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1115) FimP PF09766.4 CDI81550.1 - 0.074 12.1 21.1 0.069 12.2 14.6 1.0 1 0 0 1 1 1 0 Fms-interacting protein Baculo_PP31 PF05311.6 CDI81550.1 - 0.086 12.1 7.7 0.085 12.1 5.3 1.0 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) Fmp27_WPPW PF10359.4 CDI81550.1 - 0.15 10.3 10.0 0.17 10.2 6.9 1.0 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain UPF0565 PF10561.4 CDI81550.1 - 0.21 10.4 7.6 0.24 10.2 5.3 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0565 DUF1764 PF08576.5 CDI81550.1 - 0.26 12.0 13.7 0.3 11.8 9.5 1.0 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) DUF3449 PF11931.3 CDI81550.1 - 0.42 10.0 10.7 0.45 9.9 7.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3449) NARP1 PF12569.3 CDI81550.1 - 0.43 9.2 11.8 0.41 9.3 8.2 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 SeqA PF03925.8 CDI81550.1 - 0.48 10.0 8.0 0.52 9.9 5.6 1.0 1 0 0 1 1 1 0 SeqA protein Peptidase_S49_N PF08496.5 CDI81550.1 - 0.5 10.1 12.1 0.59 9.9 8.4 1.0 1 0 0 1 1 1 0 Peptidase family S49 N-terminal YcbB PF08664.5 CDI81550.1 - 0.59 9.9 7.3 0.62 9.8 5.1 1.0 1 0 0 1 1 1 0 YcbB domain Herpes_U44 PF04533.8 CDI81550.1 - 0.62 9.2 8.9 0.71 9.0 6.2 1.0 1 0 0 1 1 1 0 Herpes virus U44 protein DUF2828 PF11443.3 CDI81550.1 - 0.67 8.0 7.2 0.7 8.0 5.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Suf PF05843.9 CDI81550.1 - 0.7 9.5 16.4 0.69 9.5 11.4 1.0 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) PRTP PF01366.13 CDI81550.1 - 0.7 7.8 10.0 0.7 7.8 6.9 1.0 1 0 0 1 1 1 0 Herpesvirus processing and transport protein Tim54 PF11711.3 CDI81550.1 - 0.74 8.3 7.3 0.75 8.3 5.1 1.0 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 FCP1_C PF09309.5 CDI81550.1 - 0.79 8.9 13.2 1 8.6 9.2 1.3 1 0 0 1 1 1 0 FCP1, C-terminal F-protein PF00469.15 CDI81550.1 - 0.84 8.9 10.4 0.93 8.8 7.2 1.0 1 0 0 1 1 1 0 Negative factor, (F-Protein) or Nef DUF912 PF06024.7 CDI81550.1 - 0.84 9.7 7.3 0.98 9.5 5.1 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Pex14_N PF04695.8 CDI81550.1 - 0.86 9.6 14.6 0.95 9.5 10.1 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Maf1 PF09174.5 CDI81550.1 - 0.91 9.3 7.4 0.93 9.3 5.2 1.0 1 0 0 1 1 1 0 Maf1 regulator DUF1266 PF06889.6 CDI81550.1 - 0.93 9.2 9.1 0.96 9.2 6.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1266) FYDLN_acid PF09538.5 CDI81550.1 - 0.93 10.0 6.2 1 10.0 4.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) Band_3_cyto PF07565.8 CDI81550.1 - 1.1 8.7 12.4 1.1 8.6 8.6 1.0 1 0 0 1 1 1 0 Band 3 cytoplasmic domain FNIP_N PF14636.1 CDI81550.1 - 1.1 9.7 10.4 1.2 9.5 7.2 1.1 1 0 0 1 1 1 0 Folliculin-interacting protein N-terminus FLO_LFY PF01698.11 CDI81550.1 - 1.1 8.0 11.0 1.2 7.9 7.6 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein SAPS PF04499.10 CDI81550.1 - 1.2 7.7 11.5 1.2 7.6 8.0 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein BRF1 PF07741.8 CDI81550.1 - 1.2 9.4 13.4 1.4 9.1 9.3 1.1 1 0 0 1 1 1 0 Brf1-like TBP-binding domain HGTP_anticodon2 PF12745.2 CDI81550.1 - 1.2 8.2 10.0 1.2 8.1 6.9 1.0 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs DDHD PF02862.12 CDI81550.1 - 1.2 8.8 11.0 1.3 8.7 7.6 1.0 1 0 0 1 1 1 0 DDHD domain Ctr PF04145.10 CDI81550.1 - 1.3 9.1 4.9 1.2 9.1 3.4 1.1 1 0 0 1 1 1 0 Ctr copper transporter family DUF3306 PF11748.3 CDI81550.1 - 1.3 9.7 11.9 1.3 9.6 8.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3306) Afi1 PF07792.7 CDI81550.1 - 1.3 9.0 13.0 1.4 8.8 9.0 1.0 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking AAA_28 PF13521.1 CDI81550.1 - 1.3 8.9 6.6 1.5 8.7 4.6 1.1 1 0 0 1 1 1 0 AAA domain DUF4518 PF15008.1 CDI81550.1 - 1.3 7.9 10.6 1.5 7.8 7.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4518) RR_TM4-6 PF06459.7 CDI81550.1 - 1.4 8.7 14.0 1.6 8.5 9.7 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Neur_chan_memb PF02932.11 CDI81550.1 - 1.5 8.6 6.8 1.7 8.4 4.7 1.0 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region PAT1 PF09770.4 CDI81550.1 - 1.5 6.9 26.3 1.6 6.9 18.2 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DDRGK PF09756.4 CDI81550.1 - 1.5 8.1 18.5 1.7 8.0 12.9 1.1 1 0 0 1 1 1 0 DDRGK domain Topoisom_I_N PF02919.10 CDI81550.1 - 1.6 7.9 8.6 1.7 7.9 6.0 1.0 1 0 0 1 1 1 0 Eukaryotic DNA topoisomerase I, DNA binding fragment FAM60A PF15396.1 CDI81550.1 - 1.7 8.3 7.1 1.9 8.2 4.9 1.0 1 0 0 1 1 1 0 Protein Family FAM60A DUF808 PF05661.7 CDI81550.1 - 1.8 7.3 5.3 2.1 7.0 3.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF808) Conotoxin PF02950.12 CDI81550.1 - 1.9 9.3 7.6 2.4 9.0 5.3 1.2 1 0 0 1 1 1 0 Conotoxin Herpes_DNAp_acc PF04929.7 CDI81550.1 - 2 7.3 8.1 2 7.2 5.6 1.0 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Gti1_Pac2 PF09729.4 CDI81550.1 - 2 8.2 7.6 2.1 8.2 5.3 1.1 1 0 0 1 1 1 0 Gti1/Pac2 family Peptidase_S15 PF02129.13 CDI81550.1 - 2.1 7.7 8.5 2.1 7.7 5.9 1.0 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) CKAP2_C PF15297.1 CDI81550.1 - 2.2 6.9 14.3 2.5 6.8 9.9 1.0 1 0 0 1 1 1 0 Cytoskeleton-associated protein 2 C-terminus DUF3513 PF12026.3 CDI81550.1 - 2.3 7.7 16.4 2.5 7.5 11.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3513) MDFI PF15316.1 CDI81550.1 - 2.4 8.1 6.4 2.7 7.9 4.4 1.1 1 0 0 1 1 1 0 MyoD family inhibitor PBP1_TM PF14812.1 CDI81550.1 - 2.5 8.4 7.1 3.2 8.1 4.9 1.1 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal FAM176 PF14851.1 CDI81550.1 - 2.5 7.7 8.5 2.6 7.7 5.9 1.1 1 0 0 1 1 1 0 FAM176 family DUF4175 PF13779.1 CDI81550.1 - 2.6 5.6 35.0 2.5 5.6 24.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Pal1 PF08316.6 CDI81550.1 - 2.6 8.4 5.2 2.6 8.5 3.6 1.1 1 0 0 1 1 1 0 Pal1 cell morphology protein AIF_C PF14721.1 CDI81550.1 - 2.7 8.2 10.7 2.9 8.1 7.4 1.1 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term DUF3371 PF11851.3 CDI81550.1 - 2.7 8.6 18.0 3.1 8.5 12.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3371) DUF3464 PF11947.3 CDI81550.1 - 2.8 7.4 9.7 3 7.2 6.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) eIF-3_zeta PF05091.7 CDI81550.1 - 2.8 6.4 13.3 2.8 6.4 9.2 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Glyco_transf_15 PF01793.11 CDI81550.1 - 2.8 6.8 10.3 3 6.7 7.1 1.0 1 0 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase DUF4557 PF15101.1 CDI81550.1 - 2.9 7.6 22.3 3.2 7.5 15.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) Trypan_glycop_C PF10659.4 CDI81550.1 - 3 8.1 10.9 3.6 7.9 7.5 1.2 1 0 0 1 1 1 0 Trypanosome variant surface glycoprotein C-terminal domain Dala_Dala_lig_N PF01820.16 CDI81550.1 - 3 8.1 7.0 3.4 7.9 4.9 1.1 1 0 0 1 1 1 0 D-ala D-ala ligase N-terminus DUF3492 PF11997.3 CDI81550.1 - 3.1 7.2 7.0 3.5 7.1 4.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3492) DUF2203 PF09969.4 CDI81550.1 - 3.1 8.0 9.3 3.4 7.8 6.4 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) ATAD4 PF15321.1 CDI81550.1 - 3.2 8.8 11.1 3.8 8.5 7.7 1.2 1 0 0 1 1 1 0 ATPase family AAA domain containing 4 AUX_IAA PF02309.11 CDI81550.1 - 3.2 7.4 9.3 3.5 7.3 6.5 1.0 1 0 0 1 1 1 0 AUX/IAA family DUF2201_N PF13203.1 CDI81550.1 - 3.5 6.7 12.1 3.3 6.7 8.4 1.0 1 0 0 1 1 1 0 Putative metallopeptidase domain DUF3043 PF11241.3 CDI81550.1 - 3.5 7.1 8.4 3.9 7.0 5.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) CPSF100_C PF13299.1 CDI81550.1 - 3.6 7.7 9.9 3.7 7.6 6.8 1.1 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal DUF3276 PF11680.3 CDI81550.1 - 3.6 7.3 11.0 4.3 7.1 7.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3276) EIIBC-GUT_N PF03612.9 CDI81550.1 - 3.7 7.1 11.0 4.1 6.9 7.6 1.0 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus TT_ORF1 PF02956.9 CDI81550.1 - 3.8 5.8 9.0 3.9 5.8 6.3 1.0 1 0 0 1 1 1 0 TT viral orf 1 YABBY PF04690.8 CDI81550.1 - 4.2 7.5 6.7 4.3 7.5 4.7 1.1 1 0 0 1 1 1 0 YABBY protein MCPVI PF02993.9 CDI81550.1 - 4.2 7.4 12.3 4.7 7.2 8.5 1.0 1 0 0 1 1 1 0 Minor capsid protein VI Paf1 PF03985.8 CDI81550.1 - 4.3 5.9 18.3 4.5 5.8 12.7 1.0 1 0 0 1 1 1 0 Paf1 TraH_2 PF06871.6 CDI81550.1 - 4.4 6.6 6.4 4.7 6.6 4.4 1.0 1 0 0 1 1 1 0 TraH_2 DUF3533 PF12051.3 CDI81550.1 - 4.5 5.9 7.3 4.4 5.9 5.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3533) Hid1 PF12722.2 CDI81550.1 - 4.7 4.7 13.5 5 4.6 9.4 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DHHW PF14286.1 CDI81550.1 - 4.7 6.4 9.5 5 6.3 6.6 1.0 1 0 0 1 1 1 0 DHHW protein CRF1 PF10380.4 CDI81550.1 - 4.8 7.5 9.2 5.3 7.4 6.4 1.1 1 0 0 1 1 1 0 Transcription factor CRF1 LIM_bind PF01803.11 CDI81550.1 - 4.8 6.2 14.1 4.8 6.2 9.7 1.0 1 0 0 1 1 1 0 LIM-domain binding protein PH_4 PF15404.1 CDI81550.1 - 5.1 6.5 10.1 5.5 6.4 7.0 1.1 1 0 0 1 1 1 0 Pleckstrin homology domain DUF3408 PF11888.3 CDI81550.1 - 5.3 6.9 12.7 6.4 6.7 8.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) Glyco_transf_6 PF03414.8 CDI81550.1 - 6.1 5.1 7.3 6.4 5.1 5.1 1.0 1 0 0 1 1 1 0 Glycosyltransferase family 6 DUF2126 PF09899.4 CDI81550.1 - 6.7 4.6 8.6 6.6 4.6 5.9 1.0 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) Bap31 PF05529.7 CDI81550.1 - 6.8 6.1 11.7 7.6 5.9 8.1 1.1 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like Folliculin PF11704.3 CDI81550.1 - 7.1 6.1 8.9 8.4 5.9 6.2 1.2 1 0 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport Paramyxo_ncap PF00973.14 CDI81550.1 - 7.1 5.2 8.1 6.9 5.2 5.6 1.0 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Het-C PF07217.6 CDI81550.1 - 7.1 4.6 8.6 7.4 4.6 6.0 1.0 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C CagX PF03524.10 CDI81550.1 - 7.2 5.8 9.7 8 5.6 6.8 1.1 1 0 0 1 1 1 0 Conjugal transfer protein Endonuc_Holl PF10107.4 CDI81550.1 - 7.2 6.2 12.5 7.7 6.1 8.7 1.1 1 0 0 1 1 1 0 Endonuclease related to archaeal Holliday junction resolvase Peroxin-13_N PF04088.8 CDI81550.1 - 7.3 6.5 8.0 8.6 6.3 5.6 1.1 1 0 0 1 1 1 0 Peroxin 13, N-terminal region Peptidase_U57 PF05582.7 CDI81550.1 - 8 5.3 10.0 8.6 5.2 6.9 1.0 1 0 0 1 1 1 0 YabG peptidase U57 V_ATPase_I PF01496.14 CDI81550.1 - 8.1 4.1 9.3 8.4 4.1 6.4 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family eIF_4EBP PF05456.6 CDI81550.1 - 8.3 6.1 11.1 10 5.8 7.7 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) Folate_carrier PF01770.13 CDI81550.1 - 8.4 4.7 9.1 8.9 4.7 6.3 1.0 1 0 0 1 1 1 0 Reduced folate carrier Spore_coat_CotO PF14153.1 CDI81550.1 - 8.4 5.7 21.5 9.1 5.6 14.9 1.0 1 0 0 1 1 1 0 Spore coat protein CotO DUF3260 PF11658.3 CDI81550.1 - 8.5 4.3 10.3 9.1 4.2 7.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3260) DUF775 PF05603.7 CDI81550.1 - 9 5.7 14.7 10 5.5 10.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF775) RED_N PF07808.8 CDI81550.1 - 9.4 5.3 23.8 11 5.1 16.5 1.0 1 0 0 1 1 1 0 RED-like protein N-terminal region Fmp27 PF10344.4 CDI81550.1 - 9.8 3.7 9.5 9.6 3.7 6.6 1.0 1 0 0 1 1 1 0 Mitochondrial protein from FMP27 Gag_spuma PF03276.9 CDI81550.1 - 9.9 4.3 23.6 10 4.3 16.4 1.0 1 0 0 1 1 1 0 Spumavirus gag protein DsrH PF04077.7 CDI81553.1 - 0.043 13.4 0.2 0.043 13.4 0.1 2.7 2 1 1 3 3 3 0 DsrH like protein Pribosyltran PF00156.22 CDI81553.1 - 0.21 11.3 2.0 0.66 9.7 1.0 2.2 1 1 0 1 1 1 0 Phosphoribosyl transferase domain Hydrolase PF00702.21 CDI81553.1 - 0.33 11.3 5.2 0.29 11.5 2.1 2.1 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Oxidored_q6 PF01058.17 CDI81553.1 - 1.1 8.8 4.9 0.26 10.8 1.0 1.7 1 1 1 2 2 2 0 NADH ubiquinone oxidoreductase, 20 Kd subunit FimP PF09766.4 CDI81554.1 - 0.043 12.8 44.8 0.44 9.5 10.3 2.2 2 0 0 2 2 2 0 Fms-interacting protein SOBP PF15279.1 CDI81554.1 - 0.085 13.2 26.3 0.11 12.9 18.2 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein FYDLN_acid PF09538.5 CDI81554.1 - 0.13 12.8 19.5 0.49 10.9 4.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) Ebola_NP PF05505.7 CDI81554.1 - 0.84 7.6 34.7 0.96 7.4 24.1 1.0 1 0 0 1 1 1 0 Ebola nucleoprotein SelP_N PF04592.9 CDI81554.1 - 1.2 8.5 36.4 0.2 10.9 14.3 2.1 2 0 0 2 2 2 0 Selenoprotein P, N terminal region RIC3 PF15361.1 CDI81554.1 - 2.6 8.2 30.6 4.2 7.5 11.9 2.2 2 0 0 2 2 2 0 Resistance to inhibitors of cholinesterase homologue 3 Peptidase_S49_N PF08496.5 CDI81554.1 - 4.7 6.9 27.8 0.23 11.2 5.7 2.1 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Spore_coat_CotO PF14153.1 CDI81554.1 - 5.6 6.3 43.0 3.8 6.9 9.9 2.2 2 0 0 2 2 2 0 Spore coat protein CotO PAT1 PF09770.4 CDI81554.1 - 7.9 4.5 67.2 10 4.2 46.6 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF1764 PF08576.5 CDI81554.1 - 8.4 7.2 32.9 3.1 8.6 8.7 2.4 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF1764) IncA PF04156.9 CDI81554.1 - 9.3 5.7 49.5 13 5.2 34.3 1.3 1 0 0 1 1 1 0 IncA protein AIF_C PF14721.1 CDI81554.1 - 9.4 6.4 27.0 2.2 8.5 7.1 2.3 2 0 0 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term cwf18 PF08315.7 CDI81554.1 - 9.4 6.7 27.4 0.044 14.2 5.5 2.2 2 0 0 2 2 2 0 cwf18 pre-mRNA splicing factor MIP-T3 PF10243.4 CDI81557.1 - 2.2 6.6 64.4 2.8 6.3 44.7 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 BAF1_ABF1 PF04684.8 CDI81562.1 - 5.1e-05 22.3 20.4 5.1e-05 22.3 14.2 4.0 2 2 1 4 4 4 2 BAF1 / ABF1 chromatin reorganising factor Bud13 PF09736.4 CDI81562.1 - 1.1 9.4 34.2 1.9 8.7 6.6 2.5 2 0 0 2 2 2 0 Pre-mRNA-splicing factor of RES complex DUF3439 PF11921.3 CDI81562.1 - 1.9 8.2 14.9 0.23 11.2 0.7 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF3439) DDRGK PF09756.4 CDI81562.1 - 3.4 7.0 38.0 0.44 9.9 6.7 2.3 2 0 0 2 2 2 0 DDRGK domain DivIC PF04977.10 CDI81562.1 - 3.5 7.1 41.8 3.4 7.2 0.0 3.4 3 0 0 3 3 3 0 Septum formation initiator SR-25 PF10500.4 CDI81562.1 - 4.5 6.6 58.4 0.21 11.0 20.1 3.2 2 1 1 3 3 3 0 Nuclear RNA-splicing-associated protein SR-25 PF10500.4 CDI81565.1 - 6.5e-06 25.7 6.8 6.5e-06 25.7 4.7 2.5 2 1 0 2 2 2 1 Nuclear RNA-splicing-associated protein PIN_4 PF13638.1 CDI81565.1 - 1.9 8.5 5.5 0.65 10.0 0.8 2.0 2 0 0 2 2 2 0 PIN domain SPX PF03105.14 CDI81565.1 - 2.3 7.9 20.8 1.8 8.2 3.1 2.1 2 0 0 2 2 2 0 SPX domain FLO_LFY PF01698.11 CDI81565.1 - 3 6.6 15.4 1.7 7.3 4.8 2.1 2 0 0 2 2 2 0 Floricaula / Leafy protein DUF3801 PF12687.2 CDI81565.1 - 3.4 7.1 14.2 0.022 14.3 2.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3801) FimP PF09766.4 CDI81565.1 - 3.6 6.5 17.6 0.83 8.6 7.8 2.0 2 0 0 2 2 2 0 Fms-interacting protein AAR2 PF05282.6 CDI81565.1 - 6.7 5.5 14.5 5.5 5.8 1.2 2.0 2 0 0 2 2 2 0 AAR2 protein RR_TM4-6 PF06459.7 CDI81567.1 - 0.03 14.2 0.0 0.03 14.2 0.0 5.3 4 1 1 5 5 5 0 Ryanodine Receptor TM 4-6 NAD_binding_8 PF13450.1 CDI81569.1 - 5.5e-09 35.9 0.0 1.4e-08 34.6 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 CDI81569.1 - 3.1e-06 26.3 0.1 8.5e-06 24.8 0.0 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 CDI81569.1 - 0.00011 22.0 0.4 0.00032 20.5 0.3 1.9 1 1 0 1 1 1 1 FAD-NAD(P)-binding SR-25 PF10500.4 CDI81569.1 - 0.00021 20.8 14.2 0.00021 20.8 9.8 3.9 3 1 0 3 3 2 1 Nuclear RNA-splicing-associated protein Pyr_redox_3 PF13738.1 CDI81569.1 - 0.00029 20.9 0.1 0.00029 20.9 0.1 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase TSA PF03249.8 CDI81569.1 - 0.00083 18.0 7.0 0.00083 18.0 4.9 2.2 2 0 0 2 2 1 1 Type specific antigen Strep_67kDa_ant PF06100.6 CDI81569.1 - 0.0011 17.4 0.0 0.0018 16.7 0.0 1.3 1 0 0 1 1 1 1 Streptococcal 67 kDa myosin-cross-reactive antigen like family FAD_binding_2 PF00890.19 CDI81569.1 - 0.0011 17.9 0.5 0.0016 17.3 0.3 1.2 1 0 0 1 1 1 1 FAD binding domain MACPF PF01823.14 CDI81569.1 - 0.0067 16.1 0.3 0.0067 16.1 0.2 3.4 3 0 0 3 3 3 1 MAC/Perforin domain Trp_halogenase PF04820.9 CDI81569.1 - 0.044 12.4 0.0 0.078 11.5 0.0 1.4 1 0 0 1 1 1 0 Tryptophan halogenase Pyr_redox_2 PF07992.9 CDI81569.1 - 0.051 13.4 0.0 0.087 12.6 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 CDI81569.1 - 0.056 12.5 3.4 0.14 11.1 2.3 1.6 1 1 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox PF00070.22 CDI81569.1 - 0.058 13.7 0.1 0.2 12.0 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 CDI81569.1 - 0.13 11.1 0.0 0.13 11.1 0.0 1.8 2 0 0 2 2 2 0 Lycopene cyclase protein Pap_E4 PF02711.9 CDI81569.1 - 0.26 12.1 0.0 0.26 12.1 0.0 5.1 3 2 1 4 4 3 0 E4 protein Med15 PF09606.5 CDI81569.1 - 4.4 5.3 38.4 3.5 5.7 10.4 2.1 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal Pex16 PF08610.5 CDI81570.1 - 8.8 5.2 10.9 0.29 10.0 2.7 1.8 2 0 0 2 2 2 0 Peroxisomal membrane protein (Pex16) RskA PF10099.4 CDI81587.1 - 0.00071 19.3 13.1 0.00071 19.3 9.0 6.3 4 2 3 7 7 7 2 Anti-sigma-K factor rskA Ribosomal_60s PF00428.14 CDI81587.1 - 0.0039 17.5 8.6 0.0039 17.5 6.0 5.1 4 0 0 4 4 4 2 60s Acidic ribosomal protein E7 PF00527.13 CDI81587.1 - 0.03 14.4 1.4 0.03 14.4 1.0 6.3 5 1 1 6 6 6 0 E7 protein, Early protein DUF605 PF04652.11 CDI81587.1 - 3.1 7.1 53.3 1.4 8.2 20.4 3.3 3 0 0 3 3 3 0 Vta1 like Zip PF02535.17 CDI81588.1 - 0.076 12.0 14.9 0.081 11.9 10.3 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter DUF4557 PF15101.1 CDI81588.1 - 0.3 10.8 19.3 0.33 10.7 13.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) GSK-3_bind PF05350.7 CDI81588.1 - 0.38 10.1 14.6 0.45 9.9 10.1 1.0 1 0 0 1 1 1 0 Glycogen synthase kinase-3 binding Peptidase_S15 PF02129.13 CDI81588.1 - 0.47 9.8 11.3 0.53 9.6 7.9 1.0 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Gastrin PF00918.12 CDI81588.1 - 0.67 10.7 20.6 0.79 10.5 14.3 1.0 1 0 0 1 1 1 0 Gastrin/cholecystokinin family Med19 PF10278.4 CDI81588.1 - 0.71 9.5 10.5 0.76 9.4 7.3 1.1 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 AAT PF03417.11 CDI81588.1 - 0.72 9.2 14.3 0.85 9.0 9.9 1.1 1 0 0 1 1 1 0 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase DUF3450 PF11932.3 CDI81588.1 - 1.7 7.8 21.9 2.2 7.4 15.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Helicase_RecD PF05127.9 CDI81588.1 - 2.1 7.9 11.5 2.5 7.7 8.0 1.1 1 0 0 1 1 1 0 Helicase Hamartin PF04388.7 CDI81588.1 - 2.1 6.8 15.1 2.3 6.7 10.4 1.0 1 0 0 1 1 1 0 Hamartin protein MSP1_C PF07462.6 CDI81588.1 - 2.9 6.1 9.3 3 6.1 6.4 1.0 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Serinc PF03348.10 CDI81588.1 - 3.6 6.2 10.1 3.4 6.2 7.0 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) Baculo_PP31 PF05311.6 CDI81588.1 - 4.3 6.5 12.9 4.1 6.5 8.9 1.1 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) Peptidase_S49_N PF08496.5 CDI81588.1 - 4.4 7.0 8.8 4.7 6.9 6.1 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DDHD PF02862.12 CDI81588.1 - 5.2 6.7 11.7 5.2 6.7 8.1 1.1 1 0 0 1 1 1 0 DDHD domain Herpes_DNAp_acc PF04929.7 CDI81588.1 - 5.3 5.9 13.1 5.4 5.8 9.1 1.0 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Med15 PF09606.5 CDI81588.1 - 6.2 4.8 43.5 7.2 4.6 30.2 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal AUX_IAA PF02309.11 CDI81588.1 - 6.4 6.4 11.3 6.5 6.4 7.9 1.1 1 0 0 1 1 1 0 AUX/IAA family Herpes_env PF01673.13 CDI81588.1 - 8 4.8 14.6 8.8 4.7 10.2 1.1 1 0 0 1 1 1 0 Herpesvirus putative major envelope glycoprotein PSS PF03034.10 CDI81600.1 - 4.1e-52 177.3 14.5 6.6e-52 176.6 10.0 1.3 1 0 0 1 1 1 1 Phosphatidyl serine synthase DUF3357 PF11837.3 CDI81600.1 - 8.4 6.3 6.9 4.3 7.2 0.3 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF3357) NIF PF03031.13 CDI81601.1 - 6e-20 71.5 0.0 1e-19 70.7 0.0 1.4 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase HAD_2 PF13419.1 CDI81601.1 - 0.0026 17.9 0.1 0.036 14.2 0.0 2.4 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Porin_3 PF01459.17 CDI81602.1 - 7.2e-24 84.5 0.0 8.3e-24 84.3 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic porin Utp14 PF04615.8 CDI81608.1 - 0.12 10.4 65.6 0.16 10.1 45.5 1.2 1 0 0 1 1 1 0 Utp14 protein MFS_Mycoplasma PF07672.8 CDI81608.1 - 0.46 9.6 0.0 0.46 9.6 0.0 4.3 2 1 1 3 3 3 0 Mycoplasma MFS transporter DUF842 PF05811.8 CDI81611.1 - 0.0018 17.7 5.6 0.0032 16.9 3.8 1.3 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF842) Dehydrin PF00257.14 CDI81611.1 - 0.021 15.1 12.5 0.071 13.4 0.3 2.3 1 1 1 2 2 2 0 Dehydrin Plasmodium_Vir PF05795.6 CDI81611.1 - 1 8.5 4.4 1.5 7.9 3.1 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Med15 PF09606.5 CDI81611.1 - 2.2 6.3 36.6 0.63 8.1 23.6 1.3 1 1 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal TFIIA PF03153.8 CDI81611.1 - 2.4 7.9 30.6 3.4 7.4 21.2 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF2215 PF10225.4 CDI81611.1 - 5.2 6.4 9.0 7.2 5.9 6.2 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) PP_kinase_N PF13089.1 CDI81611.1 - 9.5 6.3 8.8 1.5 8.9 2.5 2.4 3 0 0 3 3 3 0 Polyphosphate kinase N-terminal domain BAF1_ABF1 PF04684.8 CDI81612.1 - 0.0025 16.7 19.3 0.0025 16.7 13.4 6.5 3 2 4 7 7 7 1 BAF1 / ABF1 chromatin reorganising factor Spt20 PF12090.3 CDI81612.1 - 0.0093 15.3 2.5 0.0093 15.3 1.7 6.4 3 2 2 5 5 5 1 Spt20 family RNA_pol_Rpb1_5 PF04998.12 CDI81612.1 - 0.13 11.4 0.0 0.13 11.4 0.0 3.1 1 1 1 2 2 2 0 RNA polymerase Rpb1, domain 5 CAF-1_p150 PF11600.3 CDI81612.1 - 0.16 11.2 82.9 0.0099 15.2 34.0 3.2 3 0 0 3 3 3 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Trichoplein PF13868.1 CDI81615.1 - 2.2e-14 52.6 60.9 2.4e-14 52.4 42.2 1.0 1 0 0 1 1 1 1 Tumour suppressor, Mitostatin DUF4509 PF14970.1 CDI81615.1 - 1.9 8.0 8.3 2.7 7.5 5.7 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4509) UPF0004 PF00919.15 CDI81620.1 - 3.7e-11 42.7 4.2 4.5e-05 23.1 0.0 3.7 3 0 0 3 3 3 2 Uncharacterized protein family UPF0004 Radical_SAM PF04055.16 CDI81620.1 - 4e-07 30.3 0.3 1.4e-06 28.5 0.1 2.0 2 0 0 2 2 2 1 Radical SAM superfamily Drc1-Sld2 PF11719.3 CDI81620.1 - 0.0012 18.0 5.5 0.0021 17.2 3.8 1.3 1 1 0 1 1 1 1 DNA replication and checkpoint protein Ribosomal_60s PF00428.14 CDI81620.1 - 0.0033 17.7 49.0 0.1 12.9 4.5 4.7 4 0 0 4 4 4 2 60s Acidic ribosomal protein Spt20 PF12090.3 CDI81620.1 - 0.016 14.6 2.6 0.03 13.6 1.8 1.4 1 0 0 1 1 1 0 Spt20 family DUF1510 PF07423.6 CDI81620.1 - 0.1 11.9 14.3 0.039 13.3 0.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) Nucleoplasmin PF03066.10 CDI81620.1 - 0.16 11.4 5.0 0.29 10.6 1.3 2.2 2 0 0 2 2 2 0 Nucleoplasmin Pex14_N PF04695.8 CDI81620.1 - 0.17 11.9 14.3 0.029 14.4 3.3 2.9 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF4011 PF13195.1 CDI81620.1 - 0.3 11.0 5.5 7.5 6.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4011) Ctr PF04145.10 CDI81620.1 - 0.5 10.4 4.6 0.24 11.4 0.1 2.4 2 1 0 2 2 2 0 Ctr copper transporter family Spt5_N PF11942.3 CDI81620.1 - 0.7 10.5 25.0 0.1 13.2 7.8 2.3 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal Suf PF05843.9 CDI81620.1 - 0.71 9.5 12.1 0.019 14.7 2.6 2.0 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) Gag_spuma PF03276.9 CDI81620.1 - 0.89 7.8 19.5 0.26 9.5 8.6 2.1 2 0 0 2 2 2 0 Spumavirus gag protein CDC45 PF02724.9 CDI81620.1 - 1.1 7.2 10.4 1.1 7.2 0.3 2.1 2 0 0 2 2 2 0 CDC45-like protein AUX_IAA PF02309.11 CDI81620.1 - 1.1 8.9 8.0 0.44 10.2 1.2 2.1 2 0 0 2 2 2 0 AUX/IAA family PBP1_TM PF14812.1 CDI81620.1 - 1.2 9.5 7.3 4.6 7.6 0.8 2.3 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal FHIPEP PF00771.15 CDI81620.1 - 1.3 7.2 4.2 1.3 7.3 0.5 2.1 2 0 0 2 2 2 0 FHIPEP family Med15 PF09606.5 CDI81620.1 - 2.4 6.2 25.5 0.018 13.2 12.1 1.4 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal RR_TM4-6 PF06459.7 CDI81620.1 - 2.8 7.7 19.2 0.25 11.2 2.1 2.2 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 DDHD PF02862.12 CDI81620.1 - 6.3 6.5 7.6 0.92 9.2 0.5 2.2 2 0 0 2 2 2 0 DDHD domain DUF4045 PF13254.1 CDI81620.1 - 6.5 5.9 13.0 7.3 5.7 1.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4045) Activator_LAG-3 PF11498.3 CDI81620.1 - 6.6 5.3 25.8 14 4.3 17.9 1.4 1 0 0 1 1 1 0 Transcriptional activator LAG-3 DUF775 PF05603.7 CDI81620.1 - 7.2 6.0 11.9 0.13 11.7 2.9 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF775) Serinc PF03348.10 CDI81620.1 - 7.4 5.1 6.6 0.66 8.6 1.2 1.6 2 0 0 2 2 2 0 Serine incorporator (Serinc) Nop53 PF07767.6 CDI81620.1 - 8.9 5.1 25.1 4.4 6.2 6.6 2.1 2 0 0 2 2 2 0 Nop53 (60S ribosomal biogenesis) Shadoo PF14999.1 CDI81624.1 - 0.012 15.5 1.6 0.012 15.5 1.1 3.3 3 0 0 3 3 3 0 Shadow of prion protein, neuroprotective Ribosomal_60s PF00428.14 CDI81624.1 - 1.5 9.3 45.6 0.46 10.8 4.2 3.4 3 0 0 3 3 3 0 60s Acidic ribosomal protein PAT1 PF09770.4 CDI81628.1 - 0.026 12.7 22.2 0.022 13.0 15.4 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Spore_coat_CotO PF14153.1 CDI81628.1 - 0.036 13.4 11.5 0.035 13.5 8.0 1.1 1 0 0 1 1 1 0 Spore coat protein CotO Bud13 PF09736.4 CDI81628.1 - 0.14 12.4 11.6 0.15 12.3 8.0 1.2 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex Activator_LAG-3 PF11498.3 CDI81628.1 - 0.19 10.4 36.8 0.18 10.5 25.5 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 RED_N PF07808.8 CDI81628.1 - 0.19 10.9 18.4 0.21 10.7 12.8 1.1 1 0 0 1 1 1 0 RED-like protein N-terminal region EIIBC-GUT_N PF03612.9 CDI81628.1 - 0.19 11.3 7.8 0.23 11.0 5.4 1.1 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus BAF1_ABF1 PF04684.8 CDI81628.1 - 0.22 10.3 30.0 0.21 10.3 20.8 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor BRF1 PF07741.8 CDI81628.1 - 0.26 11.5 7.9 0.31 11.3 5.5 1.3 1 0 0 1 1 1 0 Brf1-like TBP-binding domain DUF4557 PF15101.1 CDI81628.1 - 0.26 11.0 18.3 0.26 11.1 12.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) SpoIIIAH PF12685.2 CDI81628.1 - 0.36 10.2 11.4 0.43 10.0 7.9 1.0 1 0 0 1 1 1 0 SpoIIIAH-like protein TFIIA PF03153.8 CDI81628.1 - 0.38 10.5 19.2 0.38 10.6 13.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Peptidase_S49_N PF08496.5 CDI81628.1 - 0.62 9.8 8.0 0.75 9.5 5.5 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal CagX PF03524.10 CDI81628.1 - 0.76 9.0 9.1 0.92 8.7 6.3 1.2 1 0 0 1 1 1 0 Conjugal transfer protein FimP PF09766.4 CDI81628.1 - 1 8.3 23.4 1.2 8.0 16.2 1.1 1 0 0 1 1 1 0 Fms-interacting protein SAGA-Tad1 PF12767.2 CDI81628.1 - 1 8.9 16.8 1.1 8.8 11.7 1.1 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit DUF4175 PF13779.1 CDI81628.1 - 1.1 6.8 34.3 1.3 6.5 23.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) RR_TM4-6 PF06459.7 CDI81628.1 - 1.1 9.0 9.1 1.4 8.7 6.3 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF3373 PF11853.3 CDI81628.1 - 1.4 7.3 9.6 1.5 7.3 6.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) BNR_3 PF13859.1 CDI81628.1 - 1.5 7.7 7.4 1.6 7.6 5.2 1.0 1 0 0 1 1 1 0 BNR repeat-like domain Zip PF02535.17 CDI81628.1 - 1.6 7.6 4.8 1.4 7.8 3.3 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Band_3_cyto PF07565.8 CDI81628.1 - 1.7 8.0 11.8 1.7 8.0 8.1 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain FlaG PF03646.10 CDI81628.1 - 1.7 8.8 18.0 0.12 12.4 9.5 1.4 2 0 0 2 2 1 0 FlaG protein FLO_LFY PF01698.11 CDI81628.1 - 2.2 7.0 10.4 2.5 6.8 7.2 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein DUF853 PF05872.7 CDI81628.1 - 2.4 6.3 7.7 2.4 6.3 5.4 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) DUF775 PF05603.7 CDI81628.1 - 2.9 7.3 13.1 3.3 7.1 9.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF775) RBP_receptor PF14752.1 CDI81628.1 - 3 6.0 9.3 3.6 5.8 6.5 1.0 1 0 0 1 1 1 0 Retinol binding protein receptor DUF1800 PF08811.6 CDI81628.1 - 3 6.6 13.5 2.8 6.7 9.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1800) eIF-3_zeta PF05091.7 CDI81628.1 - 3.2 6.2 15.9 3.4 6.1 11.0 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF3154 PF11351.3 CDI81628.1 - 3.2 7.4 6.4 4.3 7.1 4.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3154) DUF3306 PF11748.3 CDI81628.1 - 3.8 8.1 11.7 5.7 7.6 8.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3306) DDRGK PF09756.4 CDI81628.1 - 4.5 6.6 17.1 5.6 6.3 11.8 1.1 1 0 0 1 1 1 0 DDRGK domain Apc15p PF05841.6 CDI81628.1 - 4.7 7.9 21.1 6.1 7.5 14.6 1.1 1 0 0 1 1 1 0 Apc15p protein Spore_YhcN_YlaJ PF09580.5 CDI81628.1 - 4.8 7.2 10.9 4.7 7.2 7.6 1.2 1 0 0 1 1 1 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) GOLD_2 PF13897.1 CDI81628.1 - 5 7.3 10.0 6.4 7.0 6.9 1.2 1 1 0 1 1 1 0 Golgi-dynamics membrane-trafficking Peptidase_S15 PF02129.13 CDI81628.1 - 5.2 6.4 10.4 5.6 6.2 7.2 1.1 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) AFT PF08731.6 CDI81628.1 - 5.2 7.2 10.2 6 7.1 6.8 1.3 1 1 0 1 1 1 0 Transcription factor AFT FHIPEP PF00771.15 CDI81628.1 - 5.6 5.1 7.8 6.2 5.0 5.4 1.0 1 0 0 1 1 1 0 FHIPEP family Serinc PF03348.10 CDI81628.1 - 6.4 5.3 13.9 6.9 5.2 9.6 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) DUF2126 PF09899.4 CDI81628.1 - 8.2 4.3 8.3 8.5 4.2 5.8 1.0 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) PIH1 PF08190.7 CDI81628.1 - 8.8 5.6 19.2 8.8 5.6 13.3 1.0 1 0 0 1 1 1 0 pre-RNA processing PIH1/Nop17 FPN1 PF06963.7 CDI81628.1 - 9.3 4.5 6.7 9.9 4.4 4.7 1.2 1 0 0 1 1 1 0 Ferroportin1 (FPN1) BSP_II PF05432.6 CDI81632.1 - 0.25 10.5 4.1 0.33 10.1 2.8 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Adeno_PV PF03910.8 CDI81632.1 - 0.5 9.3 8.0 0.57 9.2 5.5 1.1 1 0 0 1 1 1 0 Adenovirus minor core protein PV HlyD_2 PF12700.2 CDI81632.1 - 0.83 8.7 10.5 0.85 8.7 7.3 1.0 1 0 0 1 1 1 0 HlyD family secretion protein Mucin PF01456.12 CDI81632.1 - 1.1 9.0 21.4 1.7 8.4 14.8 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein Macoilin PF09726.4 CDI81632.1 - 1.4 7.0 15.4 1.6 6.9 10.7 1.0 1 0 0 1 1 1 0 Transmembrane protein Plasmodium_Vir PF05795.6 CDI81632.1 - 1.7 7.7 6.7 1.9 7.5 4.7 1.0 1 0 0 1 1 1 0 Plasmodium vivax Vir protein SOBP PF15279.1 CDI81632.1 - 2.6 8.3 18.3 3 8.1 12.7 1.0 1 0 0 1 1 1 0 Sine oculis-binding protein DUF2052 PF09747.4 CDI81632.1 - 3.5 7.5 11.9 4.5 7.1 8.2 1.1 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) Nha1_C PF08619.5 CDI81632.1 - 8 5.6 15.9 8.5 5.5 11.0 1.0 1 0 0 1 1 1 0 Alkali metal cation/H+ antiporter Nha1 C terminus NPR3 PF03666.8 CDI81632.1 - 9 4.7 12.9 9.8 4.5 8.9 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 FimP PF09766.4 CDI81633.1 - 0.67 8.9 27.0 0.64 9.0 18.7 1.1 1 0 0 1 1 1 0 Fms-interacting protein FAM60A PF15396.1 CDI81633.1 - 2 8.1 11.2 2 8.1 7.8 1.0 1 0 0 1 1 1 0 Protein Family FAM60A AIF_C PF14721.1 CDI81633.1 - 3.8 7.7 12.8 4 7.6 8.9 1.1 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Dala_Dala_lig_N PF01820.16 CDI81633.1 - 4.3 7.6 7.6 4.7 7.5 5.2 1.2 1 0 0 1 1 1 0 D-ala D-ala ligase N-terminus DUF3408 PF11888.3 CDI81633.1 - 5.3 6.9 15.0 5.6 6.8 10.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) DUF1764 PF08576.5 CDI81633.1 - 5.4 7.8 18.1 5.7 7.7 12.6 1.1 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) Peptidase_S49_N PF08496.5 CDI81633.1 - 5.7 6.7 13.5 6.1 6.6 9.3 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Gti1_Pac2 PF09729.4 CDI81633.1 - 6.3 6.6 10.3 6.2 6.6 7.1 1.1 1 0 0 1 1 1 0 Gti1/Pac2 family Pex14_N PF04695.8 CDI81633.1 - 6.4 6.8 25.0 7.5 6.6 17.3 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region PH_4 PF15404.1 CDI81633.1 - 7.5 6.0 12.6 8.5 5.8 8.7 1.1 1 0 0 1 1 1 0 Pleckstrin homology domain DDRGK PF09756.4 CDI81633.1 - 7.6 5.8 20.7 7.4 5.9 14.3 1.1 1 0 0 1 1 1 0 DDRGK domain DUF3381 PF11861.3 CDI81633.1 - 8 5.9 17.8 8.4 5.8 12.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) FAM176 PF14851.1 CDI81633.1 - 8.9 5.9 8.5 9.1 5.9 5.9 1.2 1 0 0 1 1 1 0 FAM176 family Sox_N PF12444.3 CDI81633.1 - 8.9 7.4 10.8 12 7.0 7.5 1.2 1 0 0 1 1 1 0 Sox developmental protein N terminal HCV_NS5a_C PF12941.2 CDI81633.1 - 9.1 5.7 8.8 11 5.5 6.1 1.0 1 0 0 1 1 1 0 HCV NS5a protein C-terminal region DUF775 PF05603.7 CDI81633.1 - 9.7 5.6 17.8 10 5.6 12.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF775) PAT1 PF09770.4 CDI81633.1 - 9.9 4.2 36.1 11 4.1 25.0 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 YABBY PF04690.8 CDI81633.1 - 9.9 6.3 10.6 11 6.2 7.3 1.1 1 0 0 1 1 1 0 YABBY protein DUF4217 PF13959.1 CDI81634.1 - 4.3e-05 22.9 0.0 0.0001 21.7 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Med15 PF09606.5 CDI81634.1 - 2 6.5 42.9 2.5 6.1 29.8 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF3678 PF12435.3 CDI81634.1 - 8.5 6.0 19.0 0.15 11.6 3.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3678) Glutaredoxin PF00462.19 CDI81635.1 - 2.4e-16 59.4 0.0 3e-16 59.1 0.0 1.1 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_3 PF13192.1 CDI81635.1 - 0.00068 19.4 0.0 0.0019 17.9 0.0 1.8 1 1 0 1 1 1 1 Thioredoxin domain Thioredoxin_9 PF14595.1 CDI81635.1 - 0.0009 18.8 0.0 0.0011 18.5 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin DUF836 PF05768.9 CDI81635.1 - 0.0029 17.8 0.0 0.0056 16.9 0.0 1.6 1 1 0 1 1 1 1 Glutaredoxin-like domain (DUF836) DSBA PF01323.15 CDI81635.1 - 0.0046 16.5 0.2 0.089 12.3 0.0 2.0 2 0 0 2 2 2 1 DSBA-like thioredoxin domain Thioredoxin_4 PF13462.1 CDI81635.1 - 0.025 14.5 0.4 2.4 8.1 0.3 2.1 1 1 1 2 2 2 0 Thioredoxin Cys_rich_CPXG PF14255.1 CDI81635.1 - 0.041 13.7 0.1 0.062 13.1 0.1 1.3 1 0 0 1 1 1 0 Cysteine-rich CPXCG Thioredoxin_2 PF13098.1 CDI81635.1 - 0.11 12.7 0.4 0.6 10.3 0.3 1.9 1 1 0 1 1 1 0 Thioredoxin-like domain Thioredoxin_8 PF13905.1 CDI81635.1 - 0.12 12.4 0.1 1.6 8.8 0.0 2.0 1 1 1 2 2 2 0 Thioredoxin-like zinc_ribbon_2 PF13240.1 CDI81635.1 - 0.19 11.2 1.1 0.35 10.4 0.1 1.9 2 0 0 2 2 2 0 zinc-ribbon domain CDC37_C PF08564.5 CDI81636.1 - 0.052 13.3 0.1 0.15 11.9 0.0 1.9 1 1 1 2 2 2 0 Cdc37 C terminal domain RIO1 PF01163.17 CDI81639.1 - 4.1e-46 156.7 0.0 6.7e-46 156.0 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Rio2_N PF09202.6 CDI81639.1 - 1.2e-31 108.5 0.5 2.7e-31 107.4 0.4 1.6 1 0 0 1 1 1 1 Rio2, N-terminal APH PF01636.18 CDI81639.1 - 1.7e-09 37.8 3.5 6.4e-05 22.8 0.4 2.6 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 CDI81639.1 - 2.5e-06 26.7 0.2 6.7e-05 22.0 0.1 2.3 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family WaaY PF06176.6 CDI81639.1 - 0.0025 17.0 0.1 0.0043 16.3 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide core biosynthesis protein (WaaY) HTH_45 PF14947.1 CDI81639.1 - 0.026 14.3 0.0 0.45 10.3 0.1 2.8 3 0 0 3 3 3 0 Winged helix-turn-helix Nop14 PF04147.7 CDI81639.1 - 5.8 4.7 25.1 11 3.7 17.4 1.4 1 0 0 1 1 1 0 Nop14-like family OATP PF03137.15 CDI81640.1 - 4.1 5.3 4.6 5.7 4.8 3.2 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family MIP-T3 PF10243.4 CDI81641.1 - 1.2e-05 23.9 29.2 1.4e-05 23.7 20.2 1.1 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 DUF1777 PF08648.7 CDI81641.1 - 0.0055 16.4 101.9 0.25 11.0 27.7 2.4 1 1 1 2 2 2 2 Protein of unknown function (DUF1777) Yip1 PF04893.12 CDI81645.1 - 6.3e-06 25.8 0.1 6.3e-06 25.8 0.1 2.0 2 0 0 2 2 2 1 Yip1 domain Ribosomal_60s PF00428.14 CDI81645.1 - 0.1 13.0 10.4 0.24 11.8 7.2 1.6 1 0 0 1 1 1 0 60s Acidic ribosomal protein AP2 PF00847.15 CDI81656.1 - 0.0046 17.0 0.1 0.0046 17.0 0.0 4.8 6 1 1 7 7 7 1 AP2 domain DUF3157 PF11355.3 CDI81661.1 - 3.1 7.0 7.3 3.4 6.9 5.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3157) ENTH PF01417.15 CDI81666.1 - 5.5e-09 35.9 0.0 8.5e-09 35.3 0.0 1.3 1 0 0 1 1 1 1 ENTH domain RskA PF10099.4 CDI81667.1 - 0.005 16.6 9.1 0.0062 16.2 6.3 1.2 1 0 0 1 1 1 1 Anti-sigma-K factor rskA SR-25 PF10500.4 CDI81667.1 - 0.0059 16.1 25.5 0.013 15.0 10.9 1.9 1 1 1 2 2 2 2 Nuclear RNA-splicing-associated protein CAP59_mtransfer PF11735.3 CDI81667.1 - 0.05 12.8 7.3 0.061 12.5 5.0 1.2 1 0 0 1 1 1 0 Cryptococcal mannosyltransferase 1 MRJP PF03022.11 CDI81667.1 - 0.059 12.5 7.5 0.077 12.1 5.2 1.2 1 0 0 1 1 1 0 Major royal jelly protein PMSI1 PF15322.1 CDI81667.1 - 0.12 11.4 13.3 0.14 11.2 9.2 1.1 1 0 0 1 1 1 0 Protein missing in infertile sperm 1, putative DUF1308 PF07000.6 CDI81667.1 - 0.33 9.5 12.1 0.38 9.3 8.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1308) FLO_LFY PF01698.11 CDI81667.1 - 1.1 7.9 20.0 1.4 7.7 13.8 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein Zip PF02535.17 CDI81667.1 - 1.3 7.9 15.1 1.6 7.6 10.5 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter TALPID3 PF15324.1 CDI81667.1 - 1.4 6.1 23.2 1.7 5.8 16.0 1.0 1 0 0 1 1 1 0 Hedgehog signalling target HemX PF04375.9 CDI81667.1 - 2.1 6.8 28.1 2.4 6.6 19.4 1.0 1 0 0 1 1 1 0 HemX Mif2_N PF15624.1 CDI81667.1 - 2.2 8.8 13.3 3.1 8.4 9.2 1.2 1 0 0 1 1 1 0 Kinetochore CENP-C fungal homologue, Mif2, N-terminal DUF3801 PF12687.2 CDI81667.1 - 2.6 7.5 21.6 3.3 7.2 15.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3801) DUF844 PF05815.6 CDI81667.1 - 4.2 6.1 14.9 6.1 5.5 10.3 1.2 1 0 0 1 1 1 0 Baculovirus protein of unknown function (DUF844) Suf PF05843.9 CDI81667.1 - 4.3 6.9 23.2 6.9 6.3 16.1 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Herpes_UL87 PF03043.9 CDI81667.1 - 5 5.4 14.6 5.7 5.2 10.1 1.1 1 0 0 1 1 1 0 Herpesvirus UL87 family ETRAMP PF09716.5 CDI81667.1 - 5.7 6.9 9.1 0.75 9.7 0.3 2.3 1 1 1 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) Herpes_TK PF00693.13 CDI81667.1 - 6.7 5.7 17.1 0.021 14.0 2.0 2.0 1 1 1 2 2 2 0 Thymidine kinase from herpesvirus SprA-related PF12118.3 CDI81667.1 - 8.1 5.6 39.4 11 5.2 27.3 1.2 1 0 0 1 1 1 0 SprA-related family Macoilin PF09726.4 CDI81667.1 - 8.3 4.5 23.3 10 4.2 16.1 1.1 1 0 0 1 1 1 0 Transmembrane protein SID-1_RNA_chan PF13965.1 CDI81667.1 - 8.6 4.3 11.3 10 4.1 7.8 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 CoA_transf_3 PF02515.12 CDI81667.1 - 8.8 5.5 9.0 13 4.9 6.2 1.3 1 1 0 1 1 1 0 CoA-transferase family III DUF572 PF04502.8 CDI81671.1 - 4 6.5 20.6 4.5 6.3 14.2 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF572) DRY_EERY PF09750.4 CDI81671.1 - 4.9 7.2 15.5 5.9 7.0 10.7 1.2 1 0 0 1 1 1 0 Alternative splicing regulator TRM PF02005.11 CDI81672.1 - 2.4e-34 118.8 6.6 6.2e-21 74.7 0.0 3.5 2 1 1 4 4 4 3 N2,N2-dimethylguanosine tRNA methyltransferase HemX PF04375.9 CDI81672.1 - 5.2e-06 25.2 10.4 9.8e-06 24.3 7.2 1.5 1 0 0 1 1 1 1 HemX Spt20 PF12090.3 CDI81672.1 - 0.00036 19.9 1.9 0.00068 19.0 1.3 1.5 1 0 0 1 1 1 1 Spt20 family Borrelia_P83 PF05262.6 CDI81672.1 - 0.0042 15.4 5.8 0.0055 15.0 4.0 1.1 1 0 0 1 1 1 1 Borrelia P83/100 protein SAGA-Tad1 PF12767.2 CDI81672.1 - 0.033 13.8 12.4 0.055 13.1 8.6 1.3 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit SAPS PF04499.10 CDI81672.1 - 0.046 12.3 9.9 0.063 11.9 6.8 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Anoctamin PF04547.7 CDI81672.1 - 0.14 10.7 0.4 0.18 10.4 0.3 1.1 1 0 0 1 1 1 0 Calcium-activated chloride channel Dehydrin PF00257.14 CDI81672.1 - 0.24 11.7 20.4 0.49 10.7 14.1 1.5 1 0 0 1 1 1 0 Dehydrin DUF4557 PF15101.1 CDI81672.1 - 0.28 11.0 20.1 0.51 10.1 13.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) Zip PF02535.17 CDI81672.1 - 0.28 10.1 0.8 0.37 9.7 0.6 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter Ycf1 PF05758.7 CDI81672.1 - 0.28 8.8 12.9 0.36 8.4 8.9 1.0 1 0 0 1 1 1 0 Ycf1 DNA_pol_viral_N PF00242.12 CDI81672.1 - 0.29 10.1 17.5 0.46 9.4 12.1 1.3 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain DDRGK PF09756.4 CDI81672.1 - 0.69 9.2 21.2 1.2 8.5 14.7 1.3 1 0 0 1 1 1 0 DDRGK domain eIF-3_zeta PF05091.7 CDI81672.1 - 0.94 8.0 15.8 1.6 7.2 10.9 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Nop25 PF09805.4 CDI81672.1 - 1.4 9.0 24.0 2.3 8.3 16.6 1.3 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) RR_TM4-6 PF06459.7 CDI81672.1 - 1.5 8.6 15.0 2.8 7.7 10.4 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF2217 PF10265.4 CDI81672.1 - 1.7 7.2 14.7 2.5 6.7 10.2 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) Cwf_Cwc_15 PF04889.7 CDI81672.1 - 2.3 7.8 25.4 3.6 7.2 17.6 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Folate_carrier PF01770.13 CDI81672.1 - 2.4 6.6 5.5 3.3 6.1 3.8 1.2 1 0 0 1 1 1 0 Reduced folate carrier Plasmodium_Vir PF05795.6 CDI81672.1 - 2.4 7.2 12.8 4 6.5 8.9 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Macoilin PF09726.4 CDI81672.1 - 2.4 6.3 18.1 5 5.2 12.5 1.4 1 0 0 1 1 1 0 Transmembrane protein FLO_LFY PF01698.11 CDI81672.1 - 2.8 6.6 13.2 4.3 6.0 9.1 1.2 1 0 0 1 1 1 0 Floricaula / Leafy protein DUF755 PF05501.6 CDI81672.1 - 4 7.5 35.9 8.3 6.4 24.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF755) Pox_Ag35 PF03286.9 CDI81672.1 - 4.3 6.8 16.6 7.9 5.9 11.0 1.7 2 0 0 2 2 2 0 Pox virus Ag35 surface protein PBP1_TM PF14812.1 CDI81672.1 - 4.7 7.5 12.6 9.7 6.5 8.8 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal SRP-alpha_N PF04086.8 CDI81672.1 - 5 6.4 23.4 9.6 5.4 16.2 1.4 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Otopetrin PF03189.8 CDI81672.1 - 5.6 5.8 6.2 7.6 5.4 4.3 1.1 1 0 0 1 1 1 0 Otopetrin DUF2413 PF10310.4 CDI81672.1 - 7.7 5.2 26.6 72 2.0 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2413) Neur_chan_memb PF02932.11 CDI81672.1 - 7.7 6.3 12.9 14 5.4 8.9 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Band_3_cyto PF07565.8 CDI81672.1 - 9.9 5.5 14.1 15 4.9 9.8 1.3 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Collagen PF01391.13 CDI81673.1 - 2.8e-05 23.5 25.7 2.8e-05 23.5 17.8 3.5 5 0 0 5 5 5 1 Collagen triple helix repeat (20 copies) Cpn60_TCP1 PF00118.19 CDI81679.1 - 3.5e-06 25.9 0.0 4.8e-06 25.4 0.0 1.2 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family S1-P1_nuclease PF02265.11 CDI81679.1 - 0.0066 16.0 0.4 0.0073 15.9 0.3 1.2 1 0 0 1 1 1 1 S1/P1 Nuclease FimP PF09766.4 CDI81679.1 - 0.012 14.6 7.8 0.012 14.6 5.4 1.2 1 0 0 1 1 1 0 Fms-interacting protein KBP_C PF12309.3 CDI81679.1 - 0.013 14.4 5.2 0.015 14.2 3.6 1.0 1 0 0 1 1 1 0 KIF-1 binding protein C terminal Spt20 PF12090.3 CDI81679.1 - 0.018 14.4 4.1 0.018 14.3 2.8 1.2 1 0 0 1 1 1 0 Spt20 family Rsm1 PF08600.5 CDI81679.1 - 0.018 14.8 2.3 0.027 14.3 0.7 1.7 2 0 0 2 2 2 0 Rsm1-like FliL PF03748.9 CDI81679.1 - 0.019 14.9 0.1 0.019 14.9 0.1 2.1 2 0 0 2 2 2 0 Flagellar basal body-associated protein FliL Suf PF05843.9 CDI81679.1 - 0.023 14.4 7.9 0.026 14.2 5.4 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) SHR3_chaperone PF08229.6 CDI81679.1 - 0.031 13.2 6.0 0.036 13.0 4.2 1.1 1 0 0 1 1 1 0 ER membrane protein SH3 Peroxin-13_N PF04088.8 CDI81679.1 - 0.061 13.2 0.6 0.065 13.1 0.4 1.2 1 0 0 1 1 1 0 Peroxin 13, N-terminal region DUF4175 PF13779.1 CDI81679.1 - 0.078 10.6 17.1 0.08 10.6 11.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) OATP PF03137.15 CDI81679.1 - 0.23 9.4 1.4 0.25 9.3 1.0 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Serinc PF03348.10 CDI81679.1 - 0.46 9.1 2.8 0.5 9.0 2.0 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) LIM_bind PF01803.11 CDI81679.1 - 0.67 9.0 10.1 5.4 6.0 5.3 2.0 2 0 0 2 2 2 0 LIM-domain binding protein DUF912 PF06024.7 CDI81679.1 - 0.93 9.5 3.2 0.55 10.3 1.1 1.5 2 0 0 2 2 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) PBP1_TM PF14812.1 CDI81679.1 - 1.2 9.4 5.7 4.4 7.6 4.0 2.0 1 1 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal G0-G1_switch_2 PF15103.1 CDI81679.1 - 1.3 9.2 9.2 2.7 8.2 6.2 1.6 1 1 1 2 2 2 0 G0/G1 switch protein 2 WASH-7_C PF14746.1 CDI81679.1 - 1.5 8.3 6.1 2.5 7.7 4.2 1.3 1 0 0 1 1 1 0 WASH complex subunit 7, C-terminal MCPVI PF02993.9 CDI81679.1 - 2.3 8.2 10.8 3.1 7.8 7.5 1.1 1 0 0 1 1 1 0 Minor capsid protein VI Pex14_N PF04695.8 CDI81679.1 - 2.5 8.1 11.5 1.8 8.6 7.1 1.4 2 0 0 2 2 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region AAA_23 PF13476.1 CDI81679.1 - 3.8 7.7 8.7 4.5 7.5 6.0 1.2 1 0 0 1 1 1 0 AAA domain DUF775 PF05603.7 CDI81679.1 - 4.9 6.6 12.3 26 4.2 6.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF775) UPF0560 PF10577.4 CDI81679.1 - 5.9 5.0 11.2 7.5 4.6 7.8 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 ATAD4 PF15321.1 CDI81679.1 - 7.2 7.6 8.4 11 7.0 4.0 2.0 2 0 0 2 2 2 0 ATPase family AAA domain containing 4 Utp14 PF04615.8 CDI81681.1 - 0.091 10.9 78.1 0.051 11.7 34.8 2.4 2 0 0 2 2 2 0 Utp14 protein TRC8_N PF13705.1 CDI81681.1 - 0.82 8.1 7.3 1.8 7.0 5.0 1.6 1 1 0 1 1 1 0 TRC8 N-terminal domain RNA_pol_Rpo13 PF12136.3 CDI81681.1 - 0.9 9.2 12.4 1.6 8.4 8.6 1.4 1 0 0 1 1 1 0 RNA polymerase Rpo13 subunit HTH domain DUF3628 PF12300.3 CDI81681.1 - 1.4 8.9 19.4 8.8 6.3 8.9 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3628) MIP-T3 PF10243.4 CDI81681.1 - 3.8 5.8 89.3 0.014 13.8 36.9 3.3 3 0 0 3 3 3 0 Microtubule-binding protein MIP-T3 NPR3 PF03666.8 CDI81684.1 - 0.9 8.0 11.3 0.38 9.2 5.8 1.7 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 Apt1 PF10351.4 CDI81684.1 - 8.7 5.0 17.7 14 4.3 12.2 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF605 PF04652.11 CDI81688.1 - 0.013 14.9 24.6 0.1 11.9 0.7 2.2 2 0 0 2 2 2 0 Vta1 like AUX_IAA PF02309.11 CDI81688.1 - 0.015 15.0 1.3 0.015 15.0 0.9 2.3 2 0 0 2 2 2 0 AUX/IAA family Hid1 PF12722.2 CDI81688.1 - 0.5 7.9 23.0 0.55 7.8 6.7 2.0 2 0 0 2 2 2 0 High-temperature-induced dauer-formation protein SAPS PF04499.10 CDI81688.1 - 0.65 8.5 11.7 1 7.9 1.7 2.1 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein SRP-alpha_N PF04086.8 CDI81688.1 - 0.84 8.9 21.9 0.46 9.8 2.0 2.2 2 0 0 2 2 2 0 Signal recognition particle, alpha subunit, N-terminal DUF1675 PF07897.6 CDI81688.1 - 2.1 8.1 25.7 0.36 10.6 0.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1675) Neur_chan_memb PF02932.11 CDI81688.1 - 3 7.6 16.0 4.8 6.9 2.9 2.1 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Raftlin PF15250.1 CDI81688.1 - 3.5 6.0 15.7 0.46 8.9 0.7 2.3 2 0 0 2 2 2 0 Raftlin DUF3807 PF12720.2 CDI81688.1 - 3.9 7.5 19.3 1.4 9.0 5.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3807) SR-25 PF10500.4 CDI81691.1 - 0.24 10.8 28.5 0.15 11.5 8.1 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Apt1 PF10351.4 CDI81691.1 - 0.32 9.8 5.3 0.43 9.3 3.7 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain TraG-D_C PF12696.2 CDI81691.1 - 0.36 10.6 3.9 2.7 7.8 0.5 2.1 2 0 0 2 2 2 0 TraM recognition site of TraD and TraG Rifin_STEVOR PF02009.11 CDI81691.1 - 0.88 9.1 2.9 0.98 8.9 2.0 1.1 1 0 0 1 1 1 0 Rifin/stevor family ISG65-75 PF11727.3 CDI81691.1 - 1.2 8.0 5.5 0.26 10.2 0.1 1.9 2 0 0 2 2 2 0 Invariant surface glycoprotein TrbI PF03743.9 CDI81691.1 - 9.4 5.6 8.3 2.7 7.4 0.3 2.1 2 0 0 2 2 2 0 Bacterial conjugation TrbI-like protein Ribosomal_60s PF00428.14 CDI81695.1 - 0.0074 16.6 5.5 0.0075 16.6 3.8 1.2 1 0 0 1 1 1 1 60s Acidic ribosomal protein Med15 PF09606.5 CDI81695.1 - 0.21 9.7 13.7 0.2 9.7 9.5 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal MRP-L28 PF09812.4 CDI81695.1 - 0.57 9.9 4.5 0.68 9.7 3.1 1.1 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L28 wnt PF00110.14 CDI81705.1 - 0.0038 16.4 1.0 0.0041 16.3 0.7 1.0 1 0 0 1 1 1 1 wnt family DUF3643 PF12356.3 CDI81705.1 - 0.076 12.3 0.3 0.086 12.1 0.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3643) Sec23_helical PF04815.10 CDI81705.1 - 0.094 12.1 0.4 0.12 11.8 0.3 1.2 1 0 0 1 1 1 0 Sec23/Sec24 helical domain RAB3GAP2_N PF14655.1 CDI81705.1 - 0.095 11.6 2.6 0.1 11.5 1.8 1.0 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Atg14 PF10186.4 CDI81705.1 - 0.11 11.4 6.1 0.11 11.3 4.2 1.0 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Med15 PF09606.5 CDI81705.1 - 0.13 10.4 12.8 0.11 10.6 8.9 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal PID_2 PF14719.1 CDI81705.1 - 0.14 11.7 1.5 0.15 11.6 1.0 1.1 1 0 0 1 1 1 0 Phosphotyrosine interaction domain (PTB/PID) DUF2894 PF11445.3 CDI81705.1 - 0.16 12.2 5.3 0.18 12.0 3.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2894) RP-C_C PF11800.3 CDI81705.1 - 0.16 11.6 3.4 0.16 11.6 2.3 1.0 1 0 0 1 1 1 0 Replication protein C C-terminal region Spt20 PF12090.3 CDI81705.1 - 0.24 10.7 4.2 0.26 10.6 2.9 1.1 1 0 0 1 1 1 0 Spt20 family DNA_pol3_a_NII PF11490.3 CDI81705.1 - 0.29 10.7 9.6 0.36 10.4 6.6 1.2 1 0 0 1 1 1 0 DNA polymerase III polC-type N-terminus II Androgen_recep PF02166.11 CDI81705.1 - 0.57 8.9 5.0 0.64 8.8 3.5 1.1 1 0 0 1 1 1 0 Androgen receptor IncA PF04156.9 CDI81705.1 - 1.1 8.7 10.3 1.4 8.4 7.1 1.1 1 0 0 1 1 1 0 IncA protein TMEM154 PF15102.1 CDI81705.1 - 1.6 8.4 5.4 2 8.1 3.8 1.2 1 0 0 1 1 1 0 TMEM154 protein family DUF3987 PF13148.1 CDI81705.1 - 1.8 7.0 6.1 1.9 6.9 4.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) TSA PF03249.8 CDI81705.1 - 2.6 6.4 11.0 2.6 6.4 7.6 1.0 1 0 0 1 1 1 0 Type specific antigen DUF4407 PF14362.1 CDI81705.1 - 2.8 6.7 9.1 2.9 6.7 6.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Med3 PF11593.3 CDI81705.1 - 3.1 6.9 9.8 2.9 7.0 6.8 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DUF4199 PF13858.1 CDI81705.1 - 3.6 7.4 4.7 4.1 7.3 3.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) Macoilin PF09726.4 CDI81705.1 - 3.8 5.6 9.4 3.9 5.6 6.5 1.0 1 0 0 1 1 1 0 Transmembrane protein AAA_23 PF13476.1 CDI81705.1 - 3.9 7.7 7.9 4.7 7.4 5.4 1.2 1 0 0 1 1 1 0 AAA domain APC_CDC26 PF10471.4 CDI81705.1 - 6.5 7.5 14.8 10 6.9 10.2 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex APC subunit 1 BAF1_ABF1 PF04684.8 CDI81705.1 - 9.8 4.8 13.4 10 4.8 9.3 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Lge1 PF11488.3 CDI81708.1 - 0.043 13.9 0.5 0.052 13.7 0.4 1.3 1 0 0 1 1 1 0 Transcriptional regulatory protein LGE1 Peptidase_C1 PF00112.18 CDI81710.1 - 7.6e-50 169.8 1.8 1.2e-49 169.1 1.2 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Propeptide_C1 PF08127.8 CDI81710.1 - 0.0081 15.7 0.0 0.015 14.9 0.0 1.4 1 0 0 1 1 1 1 Peptidase family C1 propeptide SSFA2_C PF14723.1 CDI81710.1 - 0.019 14.7 1.2 0.033 13.9 0.0 1.9 3 0 0 3 3 3 0 Sperm-specific antigen 2 C-terminus Peptidase_C1_2 PF03051.10 CDI81710.1 - 0.75 8.2 1.9 11 4.3 0.0 2.1 2 0 0 2 2 2 0 Peptidase C1-like family DEAD PF00270.24 CDI81711.1 - 7.6e-15 54.8 0.0 1.3e-14 53.9 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CDI81711.1 - 2.8e-07 30.3 0.0 7.9e-07 28.8 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_25 PF13481.1 CDI81711.1 - 0.053 12.9 0.1 0.1 12.0 0.1 1.4 1 0 0 1 1 1 0 AAA domain Helicase_C PF00271.26 CDI81713.1 - 8.5e-05 22.3 0.1 0.00012 21.8 0.1 1.2 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4366 PF14283.1 CDI81723.1 - 0.026 13.9 3.5 0.035 13.5 2.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) RskA PF10099.4 CDI81723.1 - 0.042 13.5 3.2 0.051 13.3 2.2 1.2 1 0 0 1 1 1 0 Anti-sigma-K factor rskA Chloroa_b-bind PF00504.16 CDI81723.1 - 0.13 12.5 1.6 0.13 12.4 1.1 1.1 1 0 0 1 1 1 0 Chlorophyll A-B binding protein DUF1183 PF06682.7 CDI81723.1 - 0.31 10.6 10.5 0.4 10.2 7.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) DUF3357 PF11837.3 CDI81723.1 - 0.52 10.1 8.0 6.5 6.6 4.7 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3357) 7tm_2 PF00002.19 CDI81723.1 - 0.65 9.0 4.7 0.43 9.6 2.3 1.5 1 1 1 2 2 2 0 7 transmembrane receptor (Secretin family) TMEM154 PF15102.1 CDI81723.1 - 0.91 9.2 17.9 0.49 10.0 2.9 2.2 1 1 1 2 2 2 0 TMEM154 protein family DUF4512 PF14975.1 CDI81723.1 - 1.5 9.7 8.8 2.7 8.8 6.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4512) DUF572 PF04502.8 CDI81723.1 - 2.3 7.3 20.3 2.9 7.0 14.1 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF572) RNA_pol_3_Rpc31 PF11705.3 CDI81723.1 - 2.6 7.9 12.7 3 7.6 8.8 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 CDC45 PF02724.9 CDI81723.1 - 2.9 5.8 13.7 3.7 5.4 9.5 1.2 1 0 0 1 1 1 0 CDC45-like protein Plasmodium_Vir PF05795.6 CDI81723.1 - 3.1 6.8 7.2 4.1 6.4 5.0 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Glycogen_syn PF05693.8 CDI81723.1 - 3.6 5.7 8.1 3.7 5.6 5.6 1.0 1 0 0 1 1 1 0 Glycogen synthase ATP-synt_E PF05680.7 CDI81723.1 - 3.6 7.5 17.2 0.079 12.9 2.6 2.1 2 0 0 2 2 2 0 ATP synthase E chain GN3L_Grn1 PF08701.6 CDI81723.1 - 4.3 7.3 24.2 2.7 7.9 5.8 2.3 2 0 0 2 2 2 0 GNL3L/Grn1 putative GTPase MRP-S31 PF15433.1 CDI81723.1 - 4.5 6.6 21.8 5.5 6.3 15.1 1.0 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 NPR3 PF03666.8 CDI81723.1 - 5.2 5.4 17.0 6.3 5.2 11.8 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 EphA2_TM PF14575.1 CDI81723.1 - 5.4 7.4 16.3 1 9.7 2.9 2.3 1 1 1 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain AUX_IAA PF02309.11 CDI81723.1 - 5.5 6.6 15.1 6.5 6.4 10.5 1.1 1 0 0 1 1 1 0 AUX/IAA family BTV_NS2 PF04514.7 CDI81723.1 - 7.2 5.3 16.1 8.4 5.1 11.1 1.0 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 FRQ PF09421.5 CDI81723.1 - 8 4.0 14.5 9 3.9 10.1 1.0 1 0 0 1 1 1 0 Frequency clock protein GPCR_chapero_1 PF11904.3 CDI81723.1 - 8.4 5.4 14.5 10 5.1 10.0 1.1 1 0 0 1 1 1 0 GPCR-chaperone Baculo_PP31 PF05311.6 CDI81723.1 - 9.1 5.4 15.5 11 5.1 10.8 1.1 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) LAM_C PF12544.3 CDI81723.1 - 9.3 6.3 9.9 12 6.0 6.9 1.2 1 0 0 1 1 1 0 Lysine-2,3-aminomutase FimP PF09766.4 CDI81724.1 - 0.00035 19.7 10.9 0.00035 19.7 7.5 4.6 3 1 1 4 4 4 1 Fms-interacting protein Herpes_UL87 PF03043.9 CDI81724.1 - 0.087 11.1 17.3 1.3 7.3 12.0 2.3 1 1 0 1 1 1 0 Herpesvirus UL87 family PAT1 PF09770.4 CDI81724.1 - 0.91 7.6 118.0 0.0053 15.0 53.3 2.8 3 0 0 3 3 3 0 Topoisomerase II-associated protein PAT1 Pox_Ag35 PF03286.9 CDI81731.1 - 9.6 5.6 29.2 6.2 6.2 11.1 2.5 2 0 0 2 2 2 0 Pox virus Ag35 surface protein Daxx PF03344.10 CDI81733.1 - 0.035 12.6 26.0 0.043 12.3 18.0 1.0 1 0 0 1 1 1 0 Daxx Family YjgP_YjgQ PF03739.9 CDI81733.1 - 0.13 10.9 4.4 0.17 10.6 3.0 1.1 1 0 0 1 1 1 0 Predicted permease YjgP/YjgQ family Plasmodium_Vir PF05795.6 CDI81733.1 - 0.61 9.2 10.2 0.76 8.9 7.0 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Auxin_canalis PF05703.6 CDI81733.1 - 0.63 9.8 35.1 0.78 9.5 24.3 1.1 1 0 0 1 1 1 0 Auxin canalisation FUSC PF04632.7 CDI81733.1 - 0.82 8.0 25.7 1.3 7.4 17.8 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family SR-25 PF10500.4 CDI81733.1 - 2.7 7.3 48.3 0.062 12.7 15.4 2.1 1 1 1 2 2 2 0 Nuclear RNA-splicing-associated protein Utp14 PF04615.8 CDI81733.1 - 3 5.8 30.0 3.8 5.5 20.8 1.1 1 0 0 1 1 1 0 Utp14 protein NABP PF07990.7 CDI81733.1 - 3.4 6.8 24.4 4.1 6.5 16.9 1.1 1 0 0 1 1 1 0 Nucleic acid binding protein NABP DUF4647 PF15504.1 CDI81733.1 - 4.2 6.1 28.0 5 5.8 19.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4647) Ndc1_Nup PF09531.5 CDI81733.1 - 4.3 5.6 24.9 5 5.4 17.3 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup HlyD_2 PF12700.2 CDI81733.1 - 4.6 6.2 20.3 5.8 5.9 14.0 1.2 1 0 0 1 1 1 0 HlyD family secretion protein PLRV_ORF5 PF01690.12 CDI81733.1 - 6.4 5.8 23.7 8.1 5.4 16.5 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein DUF572 PF04502.8 CDI81733.1 - 7.8 5.6 31.0 10 5.2 21.5 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) PAT1 PF09770.4 CDI81733.1 - 8.6 4.4 41.5 9.6 4.2 28.8 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Med15 PF09606.5 CDI81737.1 - 0.79 7.8 29.4 0.83 7.7 20.4 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Suf PF05843.9 CDI81737.1 - 4.4 6.9 7.8 4.5 6.9 5.4 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) R_equi_Vir PF05526.6 CDI81737.1 - 6.6 6.3 12.2 8.1 6.0 8.5 1.1 1 0 0 1 1 1 0 Rhodococcus equi virulence-associated protein SR-25 PF10500.4 CDI81738.1 - 6.6e-06 25.7 13.9 0.0029 17.1 1.6 2.5 2 0 0 2 2 2 2 Nuclear RNA-splicing-associated protein Transposase_24 PF03004.9 CDI81738.1 - 3 7.7 9.8 3.2 7.6 0.2 2.9 3 0 0 3 3 3 0 Plant transposase (Ptta/En/Spm family) Corona_nucleoca PF00937.13 CDI81738.1 - 3.2 6.6 14.4 5.1 5.9 0.6 2.2 2 0 0 2 2 2 0 Coronavirus nucleocapsid protein CAF-1_p150 PF11600.3 CDI81738.1 - 7.8 5.8 12.4 1.5 8.1 1.5 2.5 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal VTC PF09359.5 CDI81748.1 - 2.8e-86 289.0 0.0 4.2e-86 288.4 0.0 1.3 1 0 0 1 1 1 1 VTC domain DUF202 PF02656.10 CDI81748.1 - 4.1e-05 23.6 0.3 0.00012 22.1 0.2 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF202) SPX PF03105.14 CDI81748.1 - 0.0024 17.6 0.0 0.0049 16.6 0.0 1.5 1 0 0 1 1 1 1 SPX domain DUF972 PF06156.8 CDI81749.1 - 0.041 14.2 3.8 0.065 13.5 2.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF972) Ribosomal_S2 PF00318.15 CDI81749.1 - 0.098 11.8 1.3 0.13 11.4 0.9 1.1 1 0 0 1 1 1 0 Ribosomal protein S2 BBS2_C PF14782.1 CDI81749.1 - 0.1 11.1 4.2 0.14 10.6 2.9 1.1 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, C-terminal DUF3381 PF11861.3 CDI81749.1 - 0.41 10.1 6.8 0.57 9.6 4.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) DUF948 PF06103.6 CDI81749.1 - 1.2 9.0 4.4 1.8 8.4 3.1 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Ribosomal_L6 PF00347.18 CDI81750.1 - 2.2e-23 82.5 0.5 7.5e-11 42.3 0.0 2.2 2 0 0 2 2 2 2 Ribosomal protein L6 DnaJ PF00226.26 CDI81751.1 - 1.6e-10 40.5 0.5 2.4e-09 36.7 0.0 2.7 3 0 0 3 3 3 1 DnaJ domain TPR_11 PF13414.1 CDI81751.1 - 0.0005 19.6 5.1 0.2 11.3 0.1 2.7 2 0 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 CDI81751.1 - 0.21 11.6 7.1 0.5 10.4 1.5 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat Mito_carr PF00153.22 CDI81755.1 - 3.7e-42 141.9 3.0 1.4e-18 66.3 0.0 3.7 3 1 0 3 3 3 3 Mitochondrial carrier protein RNA_pol_Rpb4 PF03874.11 CDI81757.1 - 5.1e-11 42.6 0.0 5.1e-11 42.6 0.0 3.2 3 1 0 3 3 3 1 RNA polymerase Rpb4 TT_ORF2 PF02957.10 CDI81758.1 - 1 10.0 8.4 0.43 11.2 3.0 2.4 2 0 0 2 2 2 0 TT viral ORF2 Shisa PF13908.1 CDI81759.1 - 0.024 14.8 0.5 0.045 13.9 0.4 1.5 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Retrotrans_gag PF03732.12 CDI81760.1 - 0.076 13.0 0.3 0.19 11.8 0.0 1.8 2 0 0 2 2 2 0 Retrotransposon gag protein RVT_1 PF00078.22 CDI81762.1 - 1.1e-12 47.7 0.1 2.2e-12 46.7 0.1 1.5 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 CDI81763.1 - 1.2e-20 73.7 0.0 1.8e-20 73.2 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.1 CDI81763.1 - 0.077 12.5 0.1 0.58 9.7 0.1 2.1 2 0 0 2 2 2 0 Integrase core domain DUF2870 PF11069.3 CDI81765.1 - 4.2e-18 65.1 0.4 2.7e-11 43.3 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF2870) Trypsin_2 PF13365.1 CDI81767.1 - 8e-11 41.9 0.6 3.8e-10 39.8 0.1 2.6 2 0 0 2 2 2 1 Trypsin-like peptidase domain PDZ_2 PF13180.1 CDI81767.1 - 0.00012 21.8 0.2 0.00042 20.1 0.0 1.9 2 0 0 2 2 2 1 PDZ domain GN3L_Grn1 PF08701.6 CDI81768.1 - 3.5e-18 65.2 17.7 3.5e-18 65.2 12.3 3.7 3 1 0 3 3 3 1 GNL3L/Grn1 putative GTPase MMR_HSR1 PF01926.18 CDI81768.1 - 1.3e-16 60.5 0.2 1.7e-13 50.5 0.0 2.8 2 1 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.13 CDI81768.1 - 8.3e-09 34.9 0.0 1.1e-05 24.7 0.0 2.3 2 0 0 2 2 2 2 Ferrous iron transport protein B DUF258 PF03193.11 CDI81768.1 - 0.0028 16.8 0.1 0.0075 15.4 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function, DUF258 ArgK PF03308.11 CDI81768.1 - 0.019 13.7 0.1 0.082 11.6 0.1 2.1 1 0 0 1 1 1 0 ArgK protein GTP_EFTU PF00009.22 CDI81768.1 - 0.064 12.6 5.7 0.14 11.6 0.0 3.2 4 1 0 4 4 4 0 Elongation factor Tu GTP binding domain Miro PF08477.8 CDI81768.1 - 0.072 13.5 0.8 1.7 9.1 0.0 2.7 2 0 0 2 2 2 0 Miro-like protein MobB PF03205.9 CDI81768.1 - 0.077 12.6 0.1 0.24 11.0 0.1 1.9 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Dynamin_N PF00350.18 CDI81768.1 - 2.7 7.7 17.1 1.2 8.8 0.0 4.5 3 2 0 4 4 4 0 Dynamin family RRM_6 PF14259.1 CDI81771.1 - 1.1e-23 83.0 0.0 1.7e-07 31.1 0.0 4.1 3 1 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CDI81771.1 - 7.4e-20 70.3 0.0 9.3e-08 31.5 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CDI81771.1 - 8.1e-10 38.4 0.0 0.021 14.6 0.0 3.6 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) EB1 PF03271.12 CDI81775.1 - 4e-11 42.7 0.1 4e-11 42.7 0.1 2.1 2 0 0 2 2 1 1 EB1-like C-terminal motif Cwf_Cwc_15 PF04889.7 CDI81775.1 - 0.038 13.7 6.9 0.058 13.0 4.8 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein FCP1_C PF09309.5 CDI81775.1 - 0.055 12.7 15.6 0.079 12.2 10.8 1.2 1 0 0 1 1 1 0 FCP1, C-terminal DUF572 PF04502.8 CDI81775.1 - 0.081 12.1 10.1 0.1 11.8 7.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) Pol_alpha_B_N PF08418.5 CDI81775.1 - 0.11 12.0 11.6 0.14 11.6 8.0 1.3 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal Apt1 PF10351.4 CDI81775.1 - 0.13 11.1 14.1 0.38 9.5 9.8 1.7 1 1 0 1 1 1 0 Golgi-body localisation protein domain Neur_chan_memb PF02932.11 CDI81775.1 - 0.14 12.0 6.4 0.16 11.8 4.4 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Ndc1_Nup PF09531.5 CDI81775.1 - 0.39 9.0 12.6 0.46 8.8 8.7 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Plasmodium_Vir PF05795.6 CDI81775.1 - 0.55 9.3 6.1 0.7 9.0 4.2 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein DUF1183 PF06682.7 CDI81775.1 - 0.89 9.1 22.9 1.2 8.6 15.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) RAP1 PF07218.6 CDI81775.1 - 0.97 7.4 13.4 0.98 7.4 9.3 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Golgin_A5 PF09787.4 CDI81775.1 - 0.99 7.8 19.4 1.3 7.5 13.5 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 SAPS PF04499.10 CDI81775.1 - 1.2 7.7 7.1 1.4 7.4 4.9 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein PAT1 PF09770.4 CDI81775.1 - 1.5 7.0 17.3 1.8 6.7 12.0 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF2217 PF10265.4 CDI81775.1 - 1.6 7.4 16.2 2 7.0 11.2 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) DNA_pol_viral_N PF00242.12 CDI81775.1 - 2.2 7.2 21.7 2.5 7.0 15.1 1.1 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain DUF3115 PF11312.3 CDI81775.1 - 2.7 6.7 6.6 3.3 6.4 4.5 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3115) Peptidase_S64 PF08192.6 CDI81775.1 - 4 5.6 13.1 4.3 5.5 9.1 1.1 1 0 0 1 1 1 0 Peptidase family S64 DUF1675 PF07897.6 CDI81775.1 - 4.2 7.1 19.0 5.8 6.7 13.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) CAF-1_p150 PF11600.3 CDI81775.1 - 4.6 6.5 20.1 1.3 8.3 5.0 2.1 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal SOG2 PF10428.4 CDI81775.1 - 7.6 5.0 20.3 9.5 4.7 14.1 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein DUF2413 PF10310.4 CDI81775.1 - 8.7 5.0 22.2 11 4.6 15.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) EGF_2 PF07974.8 CDI81777.1 - 0.027 14.6 35.9 0.057 13.5 4.8 4.1 3 0 0 3 3 3 0 EGF-like domain BAT2_N PF07001.6 CDI81779.1 - 1.8 8.8 6.5 2.4 8.4 4.5 1.1 1 0 0 1 1 1 0 BAT2 N-terminus TPR_11 PF13414.1 CDI81781.1 - 1.3e-15 56.7 6.3 5.3e-14 51.6 2.9 2.3 2 0 0 2 2 2 1 TPR repeat U-box PF04564.10 CDI81781.1 - 2e-14 53.3 0.2 9.4e-14 51.1 0.0 2.1 2 0 0 2 2 2 1 U-box domain TPR_1 PF00515.23 CDI81781.1 - 3.4e-14 51.7 6.6 3e-05 23.4 0.1 3.3 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 CDI81781.1 - 3.3e-12 45.3 7.0 0.00041 20.0 0.7 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.1 CDI81781.1 - 1.4e-08 34.5 5.9 6e-06 26.1 1.0 2.9 1 1 2 3 3 3 3 Tetratricopeptide repeat Apc3 PF12895.2 CDI81781.1 - 5.9e-08 32.7 1.0 1e-07 31.9 0.7 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.1 CDI81781.1 - 1e-07 31.2 5.3 0.0099 15.6 0.0 3.6 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_16 PF13432.1 CDI81781.1 - 9.9e-05 22.9 11.2 0.0004 20.9 1.6 2.9 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.1 CDI81781.1 - 0.0005 19.8 2.6 0.0043 16.8 0.6 2.9 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.1 CDI81781.1 - 0.0019 18.2 0.5 0.34 11.2 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 CDI81781.1 - 0.0042 17.5 3.6 0.88 10.3 0.0 3.6 1 1 2 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 CDI81781.1 - 0.0053 17.0 3.8 0.011 16.1 1.6 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.1 CDI81781.1 - 0.01 15.7 5.7 1.1 9.3 0.2 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat Bac_DNA_binding PF00216.16 CDI81781.1 - 0.032 14.2 0.0 0.061 13.3 0.0 1.5 1 0 0 1 1 1 0 Bacterial DNA-binding protein SHNi-TPR PF10516.4 CDI81781.1 - 0.087 12.0 0.1 0.3 10.3 0.1 1.9 1 0 0 1 1 1 0 SHNi-TPR DUF3435 PF11917.3 CDI81781.1 - 0.09 11.4 0.6 0.12 11.0 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3435) TPR_7 PF13176.1 CDI81781.1 - 0.092 12.5 6.7 11 6.1 0.0 4.0 3 1 1 4 4 4 0 Tetratricopeptide repeat RPN7 PF10602.4 CDI81781.1 - 0.11 11.9 0.6 0.38 10.1 0.1 1.9 1 1 1 2 2 2 0 26S proteasome subunit RPN7 TPR_6 PF13174.1 CDI81781.1 - 0.53 10.8 2.9 18 6.0 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat ubiquitin PF00240.18 CDI81783.1 - 7.6e-35 118.1 0.4 1e-34 117.7 0.3 1.2 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_L40e PF01020.12 CDI81783.1 - 5.9e-31 105.8 10.9 9.4e-31 105.1 7.5 1.3 1 0 0 1 1 1 1 Ribosomal L40e family Rad60-SLD PF11976.3 CDI81783.1 - 8e-21 73.5 0.5 1.2e-20 72.9 0.4 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 CDI81783.1 - 1.1e-06 28.8 0.1 3.5e-06 27.1 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Telomere_Sde2 PF13019.1 CDI81783.1 - 0.00044 19.9 0.0 0.00069 19.3 0.0 1.3 1 0 0 1 1 1 1 Telomere stability and silencing TUG-UBL1 PF11470.3 CDI81783.1 - 0.015 15.2 0.0 0.023 14.6 0.0 1.4 1 0 0 1 1 1 0 GLUT4 regulating protein TUG Rad60-SLD_2 PF13881.1 CDI81783.1 - 0.016 15.0 0.0 0.033 14.0 0.0 1.6 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 CDI81783.1 - 0.021 15.0 0.0 0.022 14.9 0.0 1.2 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Fer2_3 PF13085.1 CDI81783.1 - 0.41 10.4 2.0 2.4 8.0 1.1 2.2 1 1 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain SNARE_assoc PF09335.6 CDI81784.1 - 2.3e-16 60.1 9.6 1.6e-15 57.4 4.9 2.4 2 0 0 2 2 2 1 SNARE associated Golgi protein DUF2842 PF11003.3 CDI81784.1 - 0.11 12.3 4.4 0.26 11.1 0.2 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF2842) PARG_cat PF05028.9 CDI81786.1 - 9.6e-68 228.9 0.0 1.4e-66 225.1 0.0 2.0 1 1 0 1 1 1 1 Poly (ADP-ribose) glycohydrolase (PARG) FAD_binding_4 PF01565.18 CDI81789.1 - 9.1e-24 83.5 0.2 2.5e-23 82.0 0.1 1.7 1 1 0 1 1 1 1 FAD binding domain FAD-oxidase_C PF02913.14 CDI81789.1 - 7.2e-20 71.3 0.0 1.1e-19 70.7 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain Surface_antigen PF11054.3 CDI81791.1 - 1.1e-48 165.8 2.3 1.3e-48 165.5 1.6 1.0 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen DUF3439 PF11921.3 CDI81791.1 - 0.18 11.5 8.6 0.49 10.1 6.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) zf-RING_2 PF13639.1 CDI81793.1 - 2.1e-10 40.2 12.8 4e-10 39.3 8.9 1.5 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 CDI81793.1 - 2.6e-06 27.4 8.0 6.6e-06 26.1 5.6 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 CDI81793.1 - 6.8e-06 26.0 7.1 1.3e-05 25.0 4.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CDI81793.1 - 0.00033 20.2 8.5 0.0006 19.4 5.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CDI81793.1 - 0.00052 19.6 7.1 0.0011 18.6 4.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CDI81793.1 - 0.0024 17.5 10.0 0.0047 16.6 6.9 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 CDI81793.1 - 0.0033 17.1 1.7 0.0072 16.0 1.2 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-Apc11 PF12861.2 CDI81793.1 - 0.21 11.4 7.4 0.21 11.4 3.9 1.9 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger PP_M1 PF03012.9 CDI81793.1 - 0.26 10.5 4.6 0.62 9.3 3.2 1.5 1 0 0 1 1 1 0 Phosphoprotein Plasmodium_Vir PF05795.6 CDI81793.1 - 0.32 10.1 0.4 0.86 8.7 0.3 1.6 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Serinc PF03348.10 CDI81793.1 - 0.34 9.5 2.6 0.68 8.5 1.8 1.4 1 0 0 1 1 1 0 Serine incorporator (Serinc) Band_3_cyto PF07565.8 CDI81793.1 - 0.38 10.2 3.7 1 8.7 2.5 1.7 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Macoilin PF09726.4 CDI81793.1 - 0.94 7.6 7.9 2 6.6 5.4 1.5 1 0 0 1 1 1 0 Transmembrane protein Suf PF05843.9 CDI81793.1 - 3.1 7.4 9.0 0.061 13.0 1.3 1.7 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) SIT PF15330.1 CDI81796.1 - 0.25 11.4 0.9 0.67 10.1 0.6 1.7 1 0 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT CcoS PF03597.10 CDI81796.1 - 0.56 9.7 3.0 1.2 8.6 2.1 1.5 1 0 0 1 1 1 0 Cytochrome oxidase maturation protein cbb3-type DUF202 PF02656.10 CDI81798.1 - 0.036 14.2 1.3 0.058 13.6 0.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF202) MitoNEET_N PF10660.4 CDI81798.1 - 0.037 13.9 0.3 0.085 12.7 0.2 1.6 1 0 0 1 1 1 0 Iron-containing outer mitochondrial membrane protein N-terminus RAP1 PF07218.6 CDI81822.1 - 0.0015 16.7 3.4 0.0017 16.5 2.3 1.2 1 0 0 1 1 1 1 Rhoptry-associated protein 1 (RAP-1) PAT1 PF09770.4 CDI81822.1 - 7.5 4.6 92.2 8.7 4.4 63.9 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Ribosomal_S11 PF00411.14 CDI81825.1 - 0.097 12.8 2.0 0.13 12.4 1.4 1.2 1 0 0 1 1 1 0 Ribosomal protein S11 DUF3474 PF11960.3 CDI81825.1 - 0.79 9.7 3.9 0.98 9.4 2.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3474) Activator_LAG-3 PF11498.3 CDI81825.1 - 0.8 8.3 20.6 0.9 8.2 14.3 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Med15 PF09606.5 CDI81825.1 - 3.3 5.7 23.7 3.8 5.5 16.4 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal XRCC4 PF06632.7 CDI81825.1 - 3.8 6.2 8.1 4.1 6.1 5.6 1.0 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 Cyclin PF08613.6 CDI81825.1 - 7.4 6.9 7.2 4 7.8 3.5 1.6 1 1 1 2 2 2 0 Cyclin DUF3617 PF12276.3 CDI81825.1 - 9.5 5.6 14.4 15 5.0 10.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3617) FAM60A PF15396.1 CDI81826.1 - 0.31 10.7 13.9 0.37 10.5 9.7 1.1 1 0 0 1 1 1 0 Protein Family FAM60A PPP4R2 PF09184.6 CDI81826.1 - 0.35 10.3 7.9 0.39 10.2 5.5 1.1 1 0 0 1 1 1 0 PPP4R2 Presenilin PF01080.12 CDI81826.1 - 2 7.1 15.5 2.4 6.8 10.7 1.0 1 0 0 1 1 1 0 Presenilin Herpes_DNAp_acc PF04929.7 CDI81826.1 - 3.2 6.6 15.6 3.8 6.3 10.8 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor DDHD PF02862.12 CDI81826.1 - 3.7 7.2 15.2 4.5 6.9 10.5 1.1 1 0 0 1 1 1 0 DDHD domain Med15 PF09606.5 CDI81826.1 - 4.2 5.4 58.5 4.5 5.3 40.6 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Zip PF02535.17 CDI81826.1 - 6.3 5.6 7.8 6.9 5.5 5.4 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter PMSI1 PF15322.1 CDI81826.1 - 6.8 5.6 18.0 7 5.6 12.5 1.0 1 0 0 1 1 1 0 Protein missing in infertile sperm 1, putative Pec_lyase_N PF04431.8 CDI81829.1 - 0.09 12.8 0.1 8.8 6.5 0.0 2.4 2 0 0 2 2 2 0 Pectate lyase, N terminus MerR-DNA-bind PF09278.6 CDI81829.1 - 0.24 11.8 3.8 0.41 11.0 2.6 1.4 1 0 0 1 1 1 0 MerR, DNA binding Med15 PF09606.5 CDI81831.1 - 0.34 9.0 103.2 0.45 8.6 26.3 2.1 1 1 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal RR_TM4-6 PF06459.7 CDI81839.1 - 0.021 14.7 15.7 0.024 14.5 10.9 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CDC45 PF02724.9 CDI81839.1 - 0.054 11.5 15.8 0.057 11.4 11.0 1.0 1 0 0 1 1 1 0 CDC45-like protein DUF702 PF05142.7 CDI81839.1 - 0.055 13.6 15.4 0.068 13.3 10.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF702) DUF4045 PF13254.1 CDI81839.1 - 0.15 11.3 14.9 0.16 11.2 10.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) HCO3_cotransp PF00955.16 CDI81839.1 - 0.16 10.5 5.7 0.19 10.3 4.0 1.0 1 0 0 1 1 1 0 HCO3- transporter family Peptidase_U57 PF05582.7 CDI81839.1 - 0.19 10.6 12.0 0.22 10.4 8.3 1.2 1 0 0 1 1 1 0 YabG peptidase U57 Macoilin PF09726.4 CDI81839.1 - 0.2 9.9 14.9 0.2 9.8 10.3 1.0 1 0 0 1 1 1 0 Transmembrane protein RRN3 PF05327.6 CDI81839.1 - 0.21 9.6 14.9 0.24 9.4 10.3 1.0 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 SelP_N PF04592.9 CDI81839.1 - 0.25 10.7 18.7 0.3 10.4 13.0 1.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region PAT1 PF09770.4 CDI81839.1 - 0.25 9.5 49.3 0.28 9.3 34.2 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DHHW PF14286.1 CDI81839.1 - 0.28 10.4 13.0 0.3 10.3 9.0 1.0 1 0 0 1 1 1 0 DHHW protein Zip PF02535.17 CDI81839.1 - 0.3 10.0 13.0 0.36 9.7 9.0 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Raftlin PF15250.1 CDI81839.1 - 0.31 9.5 17.4 0.35 9.3 12.0 1.0 1 0 0 1 1 1 0 Raftlin Herpes_DNAp_acc PF04929.7 CDI81839.1 - 0.31 9.9 13.3 0.36 9.7 9.2 1.0 1 0 0 1 1 1 0 Herpes DNA replication accessory factor TFIIA PF03153.8 CDI81839.1 - 0.32 10.8 34.3 0.35 10.7 23.8 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit NARP1 PF12569.3 CDI81839.1 - 0.35 9.5 17.9 0.43 9.2 12.4 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 NPR3 PF03666.8 CDI81839.1 - 0.37 9.2 17.6 0.4 9.1 12.2 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Asp-B-Hydro_N PF05279.6 CDI81839.1 - 0.45 10.3 12.9 0.49 10.2 9.0 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region DDHD PF02862.12 CDI81839.1 - 0.46 10.2 15.8 0.59 9.8 11.0 1.2 1 0 0 1 1 1 0 DDHD domain Hid1 PF12722.2 CDI81839.1 - 0.48 8.0 20.1 0.5 7.9 13.9 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF1510 PF07423.6 CDI81839.1 - 0.49 9.7 21.6 0.61 9.4 15.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) SprA-related PF12118.3 CDI81839.1 - 0.52 9.5 46.6 0.66 9.2 32.3 1.1 1 0 0 1 1 1 0 SprA-related family Spore_coat_CotO PF14153.1 CDI81839.1 - 0.55 9.6 26.7 0.66 9.3 18.5 1.1 1 0 0 1 1 1 0 Spore coat protein CotO Rtf2 PF04641.7 CDI81839.1 - 0.59 9.2 17.4 0.76 8.9 12.1 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger DUF822 PF05687.8 CDI81839.1 - 0.63 10.3 12.8 0.82 10.0 8.8 1.2 1 0 0 1 1 1 0 Plant protein of unknown function (DUF822) SAGA-Tad1 PF12767.2 CDI81839.1 - 0.66 9.5 22.6 0.86 9.2 15.6 1.2 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit AAA_11 PF13086.1 CDI81839.1 - 0.72 9.3 19.9 0.85 9.1 13.8 1.1 1 0 0 1 1 1 0 AAA domain DDRGK PF09756.4 CDI81839.1 - 0.78 9.1 27.2 0.99 8.7 18.9 1.2 1 0 0 1 1 1 0 DDRGK domain Tim54 PF11711.3 CDI81839.1 - 0.88 8.0 11.7 1 7.8 8.1 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DUF605 PF04652.11 CDI81839.1 - 0.99 8.7 26.7 1.2 8.5 18.5 1.1 1 0 0 1 1 1 0 Vta1 like RP-C_C PF11800.3 CDI81839.1 - 1.1 8.9 18.1 1.2 8.8 12.6 1.1 1 0 0 1 1 1 0 Replication protein C C-terminal region Cellulose_synt PF03552.9 CDI81839.1 - 1.2 7.3 6.8 1.2 7.3 4.7 1.0 1 0 0 1 1 1 0 Cellulose synthase FAM60A PF15396.1 CDI81839.1 - 1.2 8.7 16.7 1.4 8.5 11.6 1.1 1 0 0 1 1 1 0 Protein Family FAM60A BTV_NS2 PF04514.7 CDI81839.1 - 1.3 7.8 14.1 1.4 7.7 9.8 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 HGTP_anticodon2 PF12745.2 CDI81839.1 - 1.4 7.9 15.5 1.6 7.7 10.7 1.2 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs DUF4175 PF13779.1 CDI81839.1 - 1.4 6.5 55.4 1.7 6.2 38.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Lin-8 PF03353.10 CDI81839.1 - 1.4 8.1 21.2 1.5 7.9 14.7 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist FLO_LFY PF01698.11 CDI81839.1 - 1.5 7.6 16.7 1.6 7.4 11.6 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein Paramyxo_ncap PF00973.14 CDI81839.1 - 1.5 7.4 18.2 1.7 7.2 12.6 1.0 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein PCEMA1 PF07418.6 CDI81839.1 - 1.6 8.0 9.1 1.7 7.9 6.3 1.1 1 0 0 1 1 1 0 Acidic phosphoprotein precursor PCEMA1 DUF2201_N PF13203.1 CDI81839.1 - 1.7 7.7 20.1 1.9 7.6 13.9 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain DUF3984 PF13136.1 CDI81839.1 - 2.1 7.5 17.4 2.4 7.2 12.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3984) Kei1 PF08552.6 CDI81839.1 - 2.2 7.9 12.4 3.2 7.3 8.6 1.2 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 SPX PF03105.14 CDI81839.1 - 2.9 7.6 19.4 3.3 7.4 13.4 1.1 1 0 0 1 1 1 0 SPX domain HI0933_like PF03486.9 CDI81839.1 - 3.2 6.1 13.9 3.6 5.9 9.6 1.0 1 0 0 1 1 1 0 HI0933-like protein RNA_pol_Rpb1_5 PF04998.12 CDI81839.1 - 3.3 6.8 12.0 3.8 6.6 8.3 1.0 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 Ycf1 PF05758.7 CDI81839.1 - 3.4 5.2 21.5 3.7 5.1 14.9 1.0 1 0 0 1 1 1 0 Ycf1 CPSF100_C PF13299.1 CDI81839.1 - 4 7.5 17.1 6 7.0 11.8 1.3 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Peptidase_S15 PF02129.13 CDI81839.1 - 4.7 6.5 14.1 6.3 6.1 9.8 1.3 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Senescence_reg PF04520.8 CDI81839.1 - 5.2 7.5 13.6 6.5 7.2 9.4 1.2 1 0 0 1 1 1 0 Senescence regulator DUF4220 PF13968.1 CDI81839.1 - 5.3 6.0 13.9 6.5 5.7 9.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4220) Mem_trans PF03547.13 CDI81839.1 - 5.6 5.1 9.7 6.4 4.9 6.7 1.0 1 0 0 1 1 1 0 Membrane transport protein CDK5_activator PF03261.10 CDI81839.1 - 6 6.1 20.1 7.3 5.8 13.9 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein DUF4407 PF14362.1 CDI81839.1 - 6 5.7 21.7 7.9 5.3 15.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Calici_coat_C PF08435.6 CDI81839.1 - 6.3 6.0 15.0 7.7 5.7 10.4 1.1 1 0 0 1 1 1 0 Calicivirus coat protein C-terminal FemAB PF02388.11 CDI81839.1 - 6.3 5.3 21.0 7.4 5.1 14.5 1.0 1 0 0 1 1 1 0 FemAB family DOR PF14839.1 CDI81839.1 - 6.4 6.4 28.2 7.4 6.2 19.5 1.1 1 0 0 1 1 1 0 DOR family eIF-3_zeta PF05091.7 CDI81839.1 - 7.6 5.0 25.7 8.6 4.8 17.8 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) SpoVR PF04293.8 CDI81839.1 - 8.3 4.6 20.7 9.7 4.4 14.4 1.1 1 0 0 1 1 1 0 SpoVR like protein Ofd1_CTDD PF10637.4 CDI81839.1 - 8.8 5.3 17.5 11 5.0 12.1 1.1 1 0 0 1 1 1 0 Oxoglutarate and iron-dependent oxygenase degradation C-term Peptidase_S49_N PF08496.5 CDI81839.1 - 9.7 5.9 23.5 36 4.1 16.3 1.8 1 1 0 1 1 1 0 Peptidase family S49 N-terminal Med19 PF10278.4 CDI81839.1 - 9.8 5.8 19.5 13 5.3 13.5 1.1 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 DUF615 PF04751.9 CDI81845.1 - 0.076 12.6 0.5 0.1 12.2 0.3 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF615) IncA PF04156.9 CDI81851.1 - 0.008 15.7 19.1 0.008 15.7 13.3 3.8 3 1 0 3 3 3 1 IncA protein YjgP_YjgQ PF03739.9 CDI81851.1 - 5.7 5.5 11.5 1.7 7.3 2.5 2.4 2 0 0 2 2 2 0 Predicted permease YjgP/YjgQ family Apt1 PF10351.4 CDI81851.1 - 7.9 5.2 16.7 0.87 8.3 2.2 2.2 2 0 0 2 2 2 0 Golgi-body localisation protein domain Peptidase_C6 PF00851.13 CDI81861.1 - 0.0024 16.5 0.3 0.0028 16.3 0.2 1.0 1 0 0 1 1 1 1 Helper component proteinase Phage_sheath_1 PF04984.9 CDI81861.1 - 0.036 12.5 0.1 0.038 12.4 0.1 1.0 1 0 0 1 1 1 0 Phage tail sheath protein Ashwin PF15323.1 CDI81861.1 - 0.12 12.3 7.9 0.14 12.1 5.5 1.1 1 0 0 1 1 1 0 Developmental protein Glyco_hydro_3_C PF01915.17 CDI81861.1 - 0.73 9.3 4.0 1.2 8.6 2.8 1.4 1 1 0 1 1 1 0 Glycosyl hydrolase family 3 C-terminal domain TMEM171 PF15471.1 CDI81861.1 - 0.79 8.4 6.5 0.9 8.2 4.5 1.1 1 0 0 1 1 1 0 Transmembrane protein family 171 Pex14_N PF04695.8 CDI81861.1 - 0.88 9.6 11.7 1.1 9.2 8.1 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Presenilin PF01080.12 CDI81861.1 - 1.8 7.2 5.8 2 7.1 4.0 1.1 1 0 0 1 1 1 0 Presenilin PAP1 PF08601.5 CDI81861.1 - 1.9 8.1 14.2 1.9 8.0 9.8 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 SOG2 PF10428.4 CDI81861.1 - 1.9 7.0 13.6 2.1 6.8 9.4 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein TFIIA PF03153.8 CDI81861.1 - 2.3 8.0 9.4 2.5 7.9 6.5 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF3827 PF12877.2 CDI81861.1 - 4.1 5.3 9.7 4.5 5.2 6.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) Gag_p12 PF01141.13 CDI81861.1 - 4.2 7.5 8.9 11 6.2 6.2 1.8 1 1 0 1 1 1 0 Gag polyprotein, inner coat protein p12 FNIP_N PF14636.1 CDI81861.1 - 5.3 7.5 11.2 6.8 7.1 7.8 1.1 1 0 0 1 1 1 0 Folliculin-interacting protein N-terminus DUF2217 PF10265.4 CDI81861.1 - 5.5 5.6 9.2 6.8 5.3 6.4 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) Macoilin PF09726.4 CDI81861.1 - 5.5 5.1 13.4 6.1 4.9 9.3 1.0 1 0 0 1 1 1 0 Transmembrane protein KIAA1328 PF15369.1 CDI81861.1 - 6 6.5 10.8 6.8 6.3 7.5 1.1 1 0 0 1 1 1 0 Uncharacterised protein KIAA1328 Ribosomal_60s PF00428.14 CDI81868.1 - 0.00074 19.8 43.4 0.11 12.8 6.0 3.6 3 0 0 3 3 3 3 60s Acidic ribosomal protein Shadoo PF14999.1 CDI81868.1 - 0.12 12.2 32.4 0.44 10.3 3.1 3.2 3 0 0 3 3 3 0 Shadow of prion protein, neuroprotective DUF4342 PF14242.1 CDI81868.1 - 1.4 8.7 0.0 1.4 8.7 0.0 3.7 4 0 0 4 4 4 0 Domain of unknown function (DUF4342) Chorion_2 PF03964.10 CDI81872.1 - 0.00027 21.4 6.1 0.0062 17.0 0.2 2.4 2 0 0 2 2 2 2 Chorion family 2 DUF4207 PF13904.1 CDI81872.1 - 0.0022 17.4 9.7 0.0022 17.4 6.7 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4207) PBP1_TM PF14812.1 CDI81872.1 - 1.2 9.4 26.8 0.059 13.6 7.4 3.3 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Peptidase_S8 PF00082.17 CDI81872.1 - 3.8 6.5 6.7 0.69 9.0 1.9 1.6 1 1 0 2 2 2 0 Subtilase family RRM_1 PF00076.17 CDI81873.1 - 7e-06 25.5 0.2 7.1e-05 22.3 0.0 2.5 2 1 1 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CDI81873.1 - 0.11 12.4 0.0 0.39 10.7 0.0 1.9 1 1 1 2 2 2 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF966 PF06136.8 CDI81873.1 - 7.1 5.9 9.2 9.5 5.5 6.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Herpes_UL87 PF03043.9 CDI81874.1 - 0.08 11.3 16.1 0.083 11.2 11.1 1.0 1 0 0 1 1 1 0 Herpesvirus UL87 family Rtf2 PF04641.7 CDI81874.1 - 0.16 11.1 18.6 0.2 10.8 12.9 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger GAGA_bind PF06217.7 CDI81874.1 - 0.25 11.2 22.6 0.3 10.9 15.6 1.0 1 0 0 1 1 1 0 GAGA binding protein-like family PAT1 PF09770.4 CDI81874.1 - 0.41 8.8 64.2 0.48 8.5 44.5 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 BTV_NS2 PF04514.7 CDI81874.1 - 0.48 9.2 22.4 0.54 9.0 15.6 1.0 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Presenilin PF01080.12 CDI81874.1 - 1.1 8.0 11.4 1.3 7.7 7.9 1.1 1 0 0 1 1 1 0 Presenilin DUF4045 PF13254.1 CDI81874.1 - 1.6 7.9 19.9 1.9 7.6 13.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) FAM60A PF15396.1 CDI81874.1 - 1.8 8.2 21.4 2.3 7.9 14.9 1.1 1 0 0 1 1 1 0 Protein Family FAM60A HCO3_cotransp PF00955.16 CDI81874.1 - 2.3 6.8 7.6 2.4 6.7 5.2 1.2 1 0 0 1 1 1 0 HCO3- transporter family DUF2201_N PF13203.1 CDI81874.1 - 2.5 7.1 22.2 3.1 6.8 15.4 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain Ycf1 PF05758.7 CDI81874.1 - 2.8 5.5 24.7 3 5.4 17.1 1.1 1 0 0 1 1 1 0 Ycf1 Late_protein_L2 PF00513.13 CDI81874.1 - 3 6.5 12.9 3.7 6.2 8.9 1.1 1 0 0 1 1 1 0 Late Protein L2 DUF1675 PF07897.6 CDI81874.1 - 5.5 6.7 16.9 6.9 6.4 11.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) Membralin PF09746.4 CDI81874.1 - 7.4 5.5 15.2 9 5.2 10.5 1.1 1 0 0 1 1 1 0 Tumour-associated protein Neur_chan_memb PF02932.11 CDI81874.1 - 8.1 6.2 18.3 11 5.7 12.7 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Trypan_PARP PF05887.6 CDI81875.1 - 0.00012 21.9 3.6 0.00012 21.9 2.5 3.1 4 1 0 4 4 4 1 Procyclic acidic repetitive protein (PARP) TFIIA PF03153.8 CDI81875.1 - 0.0024 17.8 46.2 0.0024 17.8 32.0 4.0 3 1 0 3 3 3 1 Transcription factor IIA, alpha/beta subunit SDA1 PF05285.7 CDI81875.1 - 0.0046 16.2 26.2 0.0046 16.2 18.2 4.0 3 1 0 3 3 3 2 SDA1 Vfa1 PF08432.5 CDI81875.1 - 0.0056 16.7 4.4 0.0056 16.7 3.0 5.2 5 0 0 5 5 5 1 AAA-ATPase Vps4-associated protein 1 Med15 PF09606.5 CDI81875.1 - 0.074 11.2 178.8 0.0072 14.5 18.6 3.2 3 0 0 3 3 3 0 ARC105 or Med15 subunit of Mediator complex non-fungal PRP38_assoc PF12871.2 CDI81875.1 - 6.1 7.4 33.0 0.095 13.2 6.3 3.4 3 0 0 3 3 3 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term DUF1777 PF08648.7 CDI81893.1 - 0.01 15.5 28.9 0.046 13.4 9.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1777) Utp14 PF04615.8 CDI81893.1 - 0.079 11.1 54.6 0.11 10.6 37.9 1.1 1 0 0 1 1 1 0 Utp14 protein CDC45 PF02724.9 CDI81893.1 - 0.16 10.0 36.8 0.36 8.8 2.7 2.2 2 0 0 2 2 2 0 CDC45-like protein CAF-1_p150 PF11600.3 CDI81893.1 - 0.29 10.4 52.6 0.039 13.3 18.5 2.1 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Parvo_coat PF00740.13 CDI81893.1 - 7.7 5.3 52.4 11 4.8 36.3 1.2 1 0 0 1 1 1 0 Parvovirus coat protein VP2 SR-25 PF10500.4 CDI81894.1 - 0.0003 20.3 34.9 0.0012 18.3 8.7 7.0 5 1 2 7 7 7 3 Nuclear RNA-splicing-associated protein DUF755 PF05501.6 CDI81894.1 - 0.00039 20.4 31.8 0.00039 20.4 22.0 9.8 7 3 2 9 9 9 2 Domain of unknown function (DUF755) CAF-1_p150 PF11600.3 CDI81894.1 - 0.0018 17.6 34.1 0.0018 17.6 23.7 6.7 4 2 2 6 6 6 2 Chromatin assembly factor 1 complex p150 subunit, N-terminal Ribosomal_60s PF00428.14 CDI81898.1 - 0.021 15.2 7.8 0.021 15.2 5.4 2.3 2 0 0 2 2 2 0 60s Acidic ribosomal protein ETRAMP PF09716.5 CDI81921.1 - 8.7 6.3 0.0 8.7 6.3 0.0 6.5 6 2 0 6 6 6 0 Malarial early transcribed membrane protein (ETRAMP) SR-25 PF10500.4 CDI81923.1 - 0.0018 17.8 11.3 0.0018 17.8 7.8 22.9 17 5 3 22 22 22 3 Nuclear RNA-splicing-associated protein LRR_4 PF12799.2 CDI81923.1 - 0.0023 17.4 6.9 0.0023 17.4 4.8 3.3 3 1 1 4 4 4 2 Leucine Rich repeats (2 copies) Ank_4 PF13637.1 CDI81923.1 - 0.01 16.3 2.1 0.059 13.8 0.0 3.2 3 0 0 3 3 3 0 Ankyrin repeats (many copies) Ank PF00023.25 CDI81923.1 - 0.012 15.4 4.6 0.06 13.1 0.1 4.2 4 0 0 4 4 4 0 Ankyrin repeat Ank_3 PF13606.1 CDI81923.1 - 0.041 14.1 0.3 7.5 7.1 0.0 4.3 4 0 0 4 4 4 0 Ankyrin repeat Activator_LAG-3 PF11498.3 CDI81946.1 - 0.035 12.8 44.4 0.088 11.5 10.2 3.5 3 0 0 3 3 3 0 Transcriptional activator LAG-3 Rxt3 PF08642.5 CDI81946.1 - 0.2 11.9 5.6 0.5 10.6 0.0 3.0 3 0 0 3 3 3 0 Histone deacetylation protein Rxt3 CAF-1_p150 PF11600.3 CDI81946.1 - 1.4 8.2 29.9 0.11 11.8 9.9 3.2 3 0 0 3 3 3 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Corona_nucleoca PF00937.13 CDI81948.1 - 0.00012 21.1 39.4 0.00021 20.3 27.3 1.3 1 0 0 1 1 1 1 Coronavirus nucleocapsid protein HCO3_cotransp PF00955.16 CDI81948.1 - 0.017 13.8 5.9 0.018 13.7 4.1 1.3 1 0 0 1 1 1 0 HCO3- transporter family CAF-1_p150 PF11600.3 CDI81948.1 - 0.023 14.0 43.0 0.028 13.7 29.8 1.0 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal NARP1 PF12569.3 CDI81948.1 - 0.045 12.5 19.2 0.048 12.4 13.3 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 PAT1 PF09770.4 CDI81948.1 - 0.083 11.1 60.9 0.089 11.0 42.2 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 RR_TM4-6 PF06459.7 CDI81948.1 - 0.1 12.4 24.1 0.15 11.9 16.7 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF2126 PF09899.4 CDI81948.1 - 0.13 10.2 15.5 0.14 10.1 10.8 1.1 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) Raftlin PF15250.1 CDI81948.1 - 0.18 10.3 25.5 0.26 9.7 17.7 1.3 1 0 0 1 1 1 0 Raftlin Tim54 PF11711.3 CDI81948.1 - 0.21 10.1 15.0 0.23 9.9 10.4 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 SprA-related PF12118.3 CDI81948.1 - 0.31 10.3 68.3 0.41 9.9 47.3 1.0 1 0 0 1 1 1 0 SprA-related family YjgP_YjgQ PF03739.9 CDI81948.1 - 0.33 9.6 12.5 0.34 9.5 8.6 1.1 1 0 0 1 1 1 0 Predicted permease YjgP/YjgQ family Presenilin PF01080.12 CDI81948.1 - 0.47 9.2 22.9 0.53 9.0 15.9 1.1 1 0 0 1 1 1 0 Presenilin SID-1_RNA_chan PF13965.1 CDI81948.1 - 0.73 7.9 16.0 0.76 7.8 11.1 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Med15 PF09606.5 CDI81948.1 - 0.73 7.9 81.6 0.81 7.8 56.5 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Ycf1 PF05758.7 CDI81948.1 - 0.84 7.2 25.4 0.91 7.1 17.6 1.1 1 0 0 1 1 1 0 Ycf1 eIF3_subunit PF08597.5 CDI81948.1 - 1.1 8.7 25.0 1.2 8.6 17.3 1.2 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit Peptidase_S15 PF02129.13 CDI81948.1 - 1.8 7.8 17.2 2.2 7.6 11.9 1.3 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) FAM91_C PF14648.1 CDI81948.1 - 2.1 7.0 13.2 2.6 6.7 9.1 1.2 1 0 0 1 1 1 0 FAM91 C-terminus DUF853 PF05872.7 CDI81948.1 - 2.7 6.2 18.8 3.5 5.8 13.0 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) TFIIA PF03153.8 CDI81948.1 - 3.2 7.5 50.7 3.8 7.3 35.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit AAA_23 PF13476.1 CDI81948.1 - 3.6 7.8 35.7 4.3 7.6 24.8 1.1 1 0 0 1 1 1 0 AAA domain SAPS PF04499.10 CDI81948.1 - 4.3 5.8 24.3 5 5.6 16.9 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF1800 PF08811.6 CDI81948.1 - 6 5.6 28.7 6.8 5.4 19.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1800) Asp-B-Hydro_N PF05279.6 CDI81948.1 - 6 6.6 20.7 7 6.4 14.4 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region GPCR_chapero_1 PF11904.3 CDI81948.1 - 7.8 5.5 26.6 10 5.1 18.5 1.2 1 0 0 1 1 1 0 GPCR-chaperone SOBP PF15279.1 CDI81948.1 - 8.3 6.6 34.2 10 6.4 23.7 1.0 1 0 0 1 1 1 0 Sine oculis-binding protein Daxx PF03344.10 CDI81948.1 - 8.4 4.7 34.1 10 4.4 23.6 1.0 1 0 0 1 1 1 0 Daxx Family FemAB PF02388.11 CDI81948.1 - 10 4.7 27.5 13 4.3 19.0 1.1 1 0 0 1 1 1 0 FemAB family Herpes_TAF50 PF03326.8 CDI81948.1 - 10 4.9 45.0 11 4.8 31.2 1.0 1 0 0 1 1 1 0 Herpesvirus transcription activation factor (transactivator) Ycf1 PF05758.7 CDI81952.1 - 0.021 12.5 21.4 0.022 12.5 14.8 1.3 1 0 0 1 1 1 0 Ycf1 LMBR1 PF04791.11 CDI81952.1 - 0.066 11.7 8.1 0.087 11.3 5.6 1.3 1 1 0 1 1 1 0 LMBR1-like membrane protein Daxx PF03344.10 CDI81952.1 - 3.3 6.0 43.4 4.2 5.7 30.1 1.1 1 0 0 1 1 1 0 Daxx Family MIP-T3 PF10243.4 CDI81952.1 - 4.3 5.6 62.4 5.6 5.3 43.2 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 V_ATPase_I PF01496.14 CDI81952.1 - 6.8 4.4 21.7 8.1 4.1 15.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Utp14 PF04615.8 CDI81952.1 - 7.1 4.6 52.2 9 4.3 36.2 1.0 1 0 0 1 1 1 0 Utp14 protein Nop53 PF07767.6 CDI81955.1 - 0.0021 17.0 25.0 0.0023 16.9 17.3 1.0 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) ETRAMP PF09716.5 CDI81955.1 - 0.012 15.5 4.8 0.016 15.1 3.3 1.2 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) TIMELESS_C PF05029.8 CDI81955.1 - 0.069 12.0 18.0 0.073 11.9 12.5 1.0 1 0 0 1 1 1 0 Timeless protein C terminal region Conotoxin PF02950.12 CDI81955.1 - 0.1 13.3 6.8 1.8 9.3 4.7 2.0 1 1 0 1 1 1 0 Conotoxin DUF1510 PF07423.6 CDI81955.1 - 0.13 11.6 18.2 0.12 11.6 12.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) YqfQ PF14181.1 CDI81955.1 - 0.13 12.3 22.3 0.14 12.1 15.5 1.0 1 0 0 1 1 1 0 YqfQ-like protein Prog_receptor PF02161.10 CDI81955.1 - 0.15 10.8 7.0 0.15 10.8 4.9 1.0 1 0 0 1 1 1 0 Progesterone receptor Spt5_N PF11942.3 CDI81955.1 - 0.17 12.5 23.7 0.2 12.2 16.4 1.1 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal DUF2890 PF11081.3 CDI81955.1 - 0.27 11.2 20.0 0.3 11.1 13.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) RNase_H2-Ydr279 PF09468.5 CDI81955.1 - 0.31 10.1 21.0 0.33 10.1 14.5 1.0 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) HSP90 PF00183.13 CDI81955.1 - 0.39 9.0 27.0 0.42 8.9 18.7 1.0 1 0 0 1 1 1 0 Hsp90 protein TRAP_alpha PF03896.11 CDI81955.1 - 0.41 9.5 9.5 0.42 9.5 6.6 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DUF3408 PF11888.3 CDI81955.1 - 0.46 10.4 14.7 0.49 10.3 10.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) Presenilin PF01080.12 CDI81955.1 - 0.51 9.1 3.1 0.52 9.0 2.2 1.0 1 0 0 1 1 1 0 Presenilin DUF3381 PF11861.3 CDI81955.1 - 0.6 9.6 30.4 0.67 9.4 21.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) SspB PF04386.8 CDI81955.1 - 0.6 9.7 13.2 0.76 9.3 9.1 1.2 1 0 0 1 1 1 0 Stringent starvation protein B SURF2 PF05477.6 CDI81955.1 - 0.67 9.0 19.5 0.7 8.9 13.5 1.0 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) XAP5 PF04921.9 CDI81955.1 - 0.71 9.4 16.8 0.81 9.2 11.6 1.1 1 0 0 1 1 1 0 XAP5, circadian clock regulator TLP-20 PF06088.6 CDI81955.1 - 0.81 9.3 12.5 0.99 9.0 8.7 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) WBS_methylT PF12589.3 CDI81955.1 - 0.84 10.1 21.1 1.1 9.8 14.6 1.1 1 0 0 1 1 1 0 Methyltransferase involved in Williams-Beuren syndrome Herpes_DNAp_acc PF04929.7 CDI81955.1 - 0.87 8.4 18.2 0.93 8.3 12.6 1.0 1 0 0 1 1 1 0 Herpes DNA replication accessory factor CENP-B_dimeris PF09026.5 CDI81955.1 - 0.91 9.7 14.9 1.1 9.5 10.3 1.2 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Nucleoside_tran PF01733.13 CDI81955.1 - 1 8.4 7.2 1.1 8.2 5.0 1.0 1 0 0 1 1 1 0 Nucleoside transporter RNA_polI_A34 PF08208.6 CDI81955.1 - 1.3 8.7 37.6 1.4 8.5 26.1 1.0 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Usp PF00582.21 CDI81955.1 - 1.3 9.2 5.1 1.3 9.1 3.5 1.1 1 0 0 1 1 1 0 Universal stress protein family DRY_EERY PF09750.4 CDI81955.1 - 1.5 8.9 11.6 1.9 8.6 8.1 1.2 1 0 0 1 1 1 0 Alternative splicing regulator Serinc PF03348.10 CDI81955.1 - 1.6 7.3 4.3 1.6 7.3 3.0 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) Nop14 PF04147.7 CDI81955.1 - 1.6 6.5 28.6 1.8 6.3 19.8 1.0 1 0 0 1 1 1 0 Nop14-like family TEX19 PF15553.1 CDI81955.1 - 1.6 8.5 10.4 1.7 8.4 7.2 1.0 1 0 0 1 1 1 0 Testis-expressed protein 19 GAGA_bind PF06217.7 CDI81955.1 - 1.7 8.5 16.2 1.8 8.4 11.2 1.0 1 0 0 1 1 1 0 GAGA binding protein-like family DUF4448 PF14610.1 CDI81955.1 - 1.8 8.0 4.7 1.9 7.9 3.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Herpes_gE PF02480.11 CDI81955.1 - 2.1 6.4 6.9 2.3 6.3 4.8 1.0 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E eIF3_subunit PF08597.5 CDI81955.1 - 2.3 7.7 31.0 2.5 7.6 21.5 1.0 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit Cnd2 PF05786.9 CDI81955.1 - 2.6 6.4 15.8 3 6.2 11.0 1.1 1 0 0 1 1 1 0 Condensin complex subunit 2 YL1 PF05764.8 CDI81955.1 - 2.7 7.5 29.1 3.2 7.2 20.2 1.1 1 0 0 1 1 1 0 YL1 nuclear protein Pox_RNA_Pol_19 PF05320.7 CDI81955.1 - 2.7 7.6 15.8 3 7.5 11.0 1.0 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit CDC45 PF02724.9 CDI81955.1 - 3 5.7 19.3 3.2 5.6 13.4 1.0 1 0 0 1 1 1 0 CDC45-like protein Mem_trans PF03547.13 CDI81955.1 - 3.4 5.8 6.4 3.4 5.8 4.4 1.0 1 0 0 1 1 1 0 Membrane transport protein eIF-3c_N PF05470.7 CDI81955.1 - 3.9 5.4 15.2 4.1 5.3 10.6 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus AIF_C PF14721.1 CDI81955.1 - 4.2 7.6 10.2 4.5 7.5 7.0 1.1 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Folate_carrier PF01770.13 CDI81955.1 - 4.3 5.7 6.7 4.1 5.8 4.6 1.0 1 0 0 1 1 1 0 Reduced folate carrier RRN3 PF05327.6 CDI81955.1 - 4.7 5.1 11.9 4.7 5.2 8.3 1.0 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 TSGP1 PF07771.6 CDI81955.1 - 4.9 7.0 17.6 5.8 6.8 12.2 1.2 1 0 0 1 1 1 0 Tick salivary peptide group 1 Tom37_C PF11801.3 CDI81955.1 - 6.5 6.5 13.0 8.2 6.2 9.0 1.3 1 0 0 1 1 1 0 Tom37 C-terminal domain DUF1168 PF06658.7 CDI81955.1 - 7.3 6.0 30.5 8.7 5.8 21.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) VID27 PF08553.5 CDI81955.1 - 7.5 4.6 18.1 7.7 4.5 12.5 1.0 1 0 0 1 1 1 0 VID27 cytoplasmic protein PDCD2_C PF04194.8 CDI81955.1 - 7.8 6.0 15.8 8.5 5.9 10.9 1.0 1 0 0 1 1 1 0 Programmed cell death protein 2, C-terminal putative domain Fmp27 PF10344.4 CDI81955.1 - 8.2 3.9 17.3 9 3.8 12.0 1.0 1 0 0 1 1 1 0 Mitochondrial protein from FMP27 Zip PF02535.17 CDI81955.1 - 8.7 5.2 9.6 8.6 5.2 6.7 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Peptidase_C37 PF05416.7 CDI81955.1 - 9.9 4.3 12.6 10 4.2 8.7 1.0 1 0 0 1 1 1 0 Southampton virus-type processing peptidase Parvo_coat PF00740.13 CDI81964.1 - 2.4 7.0 4.0 2.8 6.7 2.8 1.0 1 0 0 1 1 1 0 Parvovirus coat protein VP2 FimP PF09766.4 CDI81968.1 - 0.0047 16.0 45.2 0.087 11.8 13.6 3.4 3 0 0 3 3 3 3 Fms-interacting protein zf-DHHC PF01529.15 CDI81968.1 - 4 6.7 12.1 3.3 7.0 1.0 3.2 3 0 0 3 3 3 0 DHHC palmitoyltransferase LpxB PF02684.10 CDI81968.1 - 5.1 5.6 16.0 0.05 12.2 5.0 1.9 2 0 0 2 2 2 0 Lipid-A-disaccharide synthetase AAA_23 PF13476.1 CDI81968.1 - 8 6.7 28.2 14 5.9 2.2 3.2 3 0 0 3 3 3 0 AAA domain Rpp20 PF12328.3 CDI81972.1 - 1.3e-07 31.3 1.0 0.091 12.4 0.0 3.1 2 1 1 3 3 3 3 Rpp20 subunit of nuclear RNase MRP and P Alba PF01918.16 CDI81972.1 - 1.9e-06 27.3 0.0 3.6e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 Alba He_PIG PF05345.7 CDI81974.1 - 0.0018 18.2 0.0 0.0042 17.0 0.0 1.6 1 0 0 1 1 1 1 Putative Ig domain Dus PF01207.12 CDI81975.1 - 1e-24 86.9 0.1 8.7e-15 54.3 0.0 2.3 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) DUF3529 PF12046.3 CDI81977.1 - 0.0086 15.1 1.0 0.017 14.1 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3529) DUF788 PF05620.6 CDI81977.1 - 0.01 15.6 3.0 0.01 15.6 2.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF788) RE_TdeIII PF09520.5 CDI81977.1 - 0.014 14.7 0.7 0.014 14.7 0.5 2.0 1 1 1 2 2 1 0 Type II restriction endonuclease, TdeIII Oleosin PF01277.12 CDI81977.1 - 0.038 13.5 0.5 0.038 13.5 0.3 2.1 2 0 0 2 2 2 0 Oleosin YqfQ PF14181.1 CDI81977.1 - 0.16 12.0 22.5 0.99 9.4 2.4 2.0 2 0 0 2 2 2 0 YqfQ-like protein U1snRNP70_N PF12220.3 CDI81977.1 - 0.18 12.1 26.3 0.24 11.7 8.4 2.1 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal AIF_C PF14721.1 CDI81977.1 - 0.25 11.5 14.8 0.14 12.4 3.3 2.0 2 0 0 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term CENP-T PF15511.1 CDI81977.1 - 0.32 10.1 15.5 0.44 9.7 10.8 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T DUF1510 PF07423.6 CDI81977.1 - 0.36 10.1 18.9 0.068 12.5 5.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) FYDLN_acid PF09538.5 CDI81977.1 - 0.37 11.3 9.6 0.35 11.4 2.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) OAD_gamma PF04277.8 CDI81977.1 - 0.43 10.9 3.0 0.73 10.2 0.1 2.0 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain FAM176 PF14851.1 CDI81977.1 - 0.68 9.6 11.7 1 9.0 4.0 2.1 2 0 0 2 2 2 0 FAM176 family DUF3899 PF13038.1 CDI81977.1 - 0.91 9.7 10.3 2.6 8.2 3.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3899) Zip PF02535.17 CDI81977.1 - 1.1 8.2 4.6 1.3 7.9 3.2 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Pap_E4 PF02711.9 CDI81977.1 - 1.2 9.9 16.4 0.39 11.5 1.7 2.1 2 0 0 2 2 2 0 E4 protein AAA_11 PF13086.1 CDI81977.1 - 1.4 8.4 15.1 1.8 8.0 10.5 1.2 1 0 0 1 1 1 0 AAA domain DUF1764 PF08576.5 CDI81977.1 - 1.4 9.7 22.5 3.8 8.3 2.1 2.1 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF1764) DUF4366 PF14283.1 CDI81977.1 - 1.7 7.9 12.7 2.8 7.2 8.8 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4366) SID-1_RNA_chan PF13965.1 CDI81977.1 - 1.8 6.6 8.2 2.3 6.3 5.7 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DUF2072 PF09845.4 CDI81977.1 - 2 8.3 11.5 0.84 9.5 3.2 2.0 2 0 0 2 2 2 0 Zn-ribbon containing protein (DUF2072) Spore_coat_CotO PF14153.1 CDI81977.1 - 3 7.2 29.4 3.7 6.9 2.8 2.1 2 0 0 2 2 2 0 Spore coat protein CotO Porph_ging PF09697.5 CDI81977.1 - 3.1 8.0 7.2 1.9 8.6 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (Porph_ging) Neur_chan_memb PF02932.11 CDI81977.1 - 3.8 7.3 11.6 4.9 6.9 8.0 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region HsdM_N PF12161.3 CDI81977.1 - 4.2 7.8 8.1 1.1 9.6 1.7 2.0 2 0 0 2 2 2 0 HsdM N-terminal domain DUF3357 PF11837.3 CDI81977.1 - 5.6 6.8 8.0 2.7 7.8 0.1 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3357) DUF2140 PF09911.4 CDI81977.1 - 6 5.9 10.7 1.1 8.3 0.6 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2140) Na_trans_assoc PF06512.8 CDI81977.1 - 7 6.5 16.4 6.7 6.6 5.9 2.0 2 0 0 2 2 2 0 Sodium ion transport-associated PSK PF06404.7 CDI81977.1 - 8.6 7.2 13.2 6.6 7.5 3.4 2.1 2 0 0 2 2 2 0 Phytosulfokine precursor protein (PSK) Herpes_UL87 PF03043.9 CDI81977.1 - 9.9 4.4 10.4 12 4.1 7.2 1.0 1 0 0 1 1 1 0 Herpesvirus UL87 family MCM PF00493.18 CDI81990.1 - 7.6e-58 195.8 5.3 4.4e-32 111.1 1.0 2.5 1 1 1 2 2 2 2 MCM2/3/5 family Mg_chelatase PF01078.16 CDI81990.1 - 2.3e-07 30.1 0.7 1.9e-05 23.9 0.0 2.6 2 1 1 3 3 3 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 CDI81990.1 - 2e-06 27.5 0.0 0.00058 19.6 0.0 2.4 1 1 1 2 2 2 2 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.21 CDI81990.1 - 0.00012 21.5 0.1 0.054 12.9 0.0 2.2 1 1 1 2 2 2 2 Sigma-54 interaction domain AAA_3 PF07726.6 CDI81990.1 - 0.0029 17.1 0.1 0.033 13.8 0.1 2.2 1 1 1 2 2 2 1 ATPase family associated with various cellular activities (AAA) tRNA_synt_1c_R2 PF04557.10 CDI81990.1 - 0.056 14.1 0.7 0.17 12.6 0.2 1.9 2 0 0 2 2 2 0 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 AAA_2 PF07724.9 CDI81990.1 - 0.11 12.3 3.8 0.84 9.5 0.0 2.8 2 1 1 3 3 3 0 AAA domain (Cdc48 subfamily) BUD22 PF09073.5 CDI81996.1 - 0.00081 18.5 21.0 0.00081 18.5 14.5 4.5 4 1 1 5 5 5 1 BUD22 TRAP_alpha PF03896.11 CDI81996.1 - 6.4 5.6 19.3 12 4.7 13.4 1.4 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Claudin_2 PF13903.1 CDI82000.1 - 0.00015 21.4 5.4 0.00015 21.4 3.7 2.6 3 0 0 3 3 3 1 PMP-22/EMP/MP20/Claudin tight junction Med15 PF09606.5 CDI82000.1 - 0.003 15.8 90.3 0.0041 15.4 62.6 1.1 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal DUF2899 PF11449.3 CDI82000.1 - 0.016 14.3 5.7 0.027 13.6 3.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2899) K_trans PF02705.11 CDI82000.1 - 0.024 13.0 6.9 0.036 12.4 4.8 1.3 1 0 0 1 1 1 0 K+ potassium transporter MSP1_C PF07462.6 CDI82000.1 - 2 6.7 18.9 3.4 5.9 13.1 1.5 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus FHIPEP PF00771.15 CDI82000.1 - 8.5 4.5 31.2 11 4.1 21.6 1.2 1 0 0 1 1 1 0 FHIPEP family DUF2721 PF11026.3 CDI82001.1 - 0.0028 17.3 6.7 0.0048 16.5 4.7 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF2721) DUF4448 PF14610.1 CDI82001.1 - 0.015 14.7 0.1 0.023 14.1 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) ATG22 PF11700.3 CDI82001.1 - 0.023 13.1 5.3 0.027 12.9 3.7 1.0 1 0 0 1 1 1 0 Vacuole effluxer Atg22 like DUF2207 PF09972.4 CDI82001.1 - 0.025 13.1 0.4 0.029 12.9 0.3 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Plasmodium_Vir PF05795.6 CDI82001.1 - 0.025 13.7 0.7 0.027 13.6 0.5 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Kei1 PF08552.6 CDI82001.1 - 0.049 13.2 13.3 0.061 12.9 9.2 1.1 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 DUF2417 PF10329.4 CDI82001.1 - 0.056 12.8 0.1 0.07 12.5 0.1 1.1 1 0 0 1 1 1 0 Region of unknown function (DUF2417) DUF4366 PF14283.1 CDI82001.1 - 0.12 11.8 9.5 0.22 10.9 6.6 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4366) DUF4064 PF13273.1 CDI82001.1 - 0.15 12.1 7.8 0.5 10.5 5.0 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF4064) BCCT PF02028.12 CDI82001.1 - 0.16 10.2 3.6 0.18 9.9 2.5 1.1 1 0 0 1 1 1 0 BCCT family transporter DUF912 PF06024.7 CDI82001.1 - 0.17 11.9 15.4 0.58 10.2 10.6 1.9 1 1 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Fig1 PF12351.3 CDI82001.1 - 0.19 11.5 2.6 0.25 11.2 1.8 1.3 1 0 0 1 1 1 0 Ca2+ regulator and membrane fusion protein Fig1 DHHW PF14286.1 CDI82001.1 - 0.45 9.7 13.8 0.53 9.5 9.5 1.1 1 0 0 1 1 1 0 DHHW protein Nucleoside_tran PF01733.13 CDI82001.1 - 0.48 9.5 5.1 0.54 9.3 3.6 1.2 1 0 0 1 1 1 0 Nucleoside transporter DUF966 PF06136.8 CDI82001.1 - 0.51 9.7 11.9 0.58 9.5 8.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Rtf2 PF04641.7 CDI82001.1 - 0.59 9.2 12.6 0.76 8.9 8.7 1.2 1 0 0 1 1 1 0 Rtf2 RING-finger BNR_3 PF13859.1 CDI82001.1 - 0.77 8.7 8.8 0.88 8.5 6.1 1.1 1 0 0 1 1 1 0 BNR repeat-like domain Glt_symporter PF03616.9 CDI82001.1 - 0.78 8.1 4.7 0.98 7.8 3.2 1.2 1 0 0 1 1 1 0 Sodium/glutamate symporter Trypan_glycop_C PF10659.4 CDI82001.1 - 0.88 9.8 12.4 0.041 14.1 4.2 1.8 1 1 1 2 2 2 0 Trypanosome variant surface glycoprotein C-terminal domain DUF95 PF01944.12 CDI82001.1 - 1.2 8.7 6.3 2.8 7.5 4.4 1.6 1 1 0 1 1 1 0 Integral membrane protein DUF95 DUF2126 PF09899.4 CDI82001.1 - 1.2 7.0 10.1 1.1 7.1 7.0 1.1 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) Peptidase_M56 PF05569.6 CDI82001.1 - 1.4 7.8 9.1 1.6 7.6 6.3 1.1 1 0 0 1 1 1 0 BlaR1 peptidase M56 DUF2930 PF11152.3 CDI82001.1 - 1.4 8.0 9.8 1.7 7.7 6.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2930) Cellulose_synt PF03552.9 CDI82001.1 - 2.1 6.5 4.7 2.2 6.4 3.2 1.1 1 0 0 1 1 1 0 Cellulose synthase Pap_E4 PF02711.9 CDI82001.1 - 2.1 9.2 12.5 0.48 11.2 6.3 1.6 2 0 0 2 2 1 0 E4 protein HCO3_cotransp PF00955.16 CDI82001.1 - 2.2 6.8 5.9 2.5 6.6 4.1 1.1 1 0 0 1 1 1 0 HCO3- transporter family HXXEE PF13787.1 CDI82001.1 - 2.3 8.6 5.8 4.6 7.6 3.8 1.8 1 1 0 1 1 1 0 Protein of unknown function with HXXEE motif Apc15p PF05841.6 CDI82001.1 - 2.7 8.7 22.9 4.6 7.9 15.9 1.4 1 1 0 1 1 1 0 Apc15p protein Pex14_N PF04695.8 CDI82001.1 - 2.7 8.0 31.6 0.037 14.0 14.7 2.0 1 1 1 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Peptidase_S64 PF08192.6 CDI82001.1 - 3.1 6.0 14.3 3.4 5.8 9.9 1.0 1 0 0 1 1 1 0 Peptidase family S64 DUF3357 PF11837.3 CDI82001.1 - 3.3 7.6 13.2 1.7 8.4 3.2 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3357) LMBR1 PF04791.11 CDI82001.1 - 3.8 5.9 7.8 4.2 5.8 5.4 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein ABC2_membrane_3 PF12698.2 CDI82001.1 - 4.3 6.2 10.7 5.1 6.0 7.5 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein Pal1 PF08316.6 CDI82001.1 - 4.7 7.6 8.4 2.9 8.3 3.8 1.9 2 0 0 2 2 2 0 Pal1 cell morphology protein 7tm_7 PF08395.7 CDI82001.1 - 5.2 5.9 10.3 6.5 5.6 7.1 1.3 1 0 0 1 1 1 0 7tm Chemosensory receptor Paramyxo_ncap PF00973.14 CDI82001.1 - 7 5.2 9.9 7.1 5.2 6.9 1.2 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein TFIIA PF03153.8 CDI82001.1 - 7.1 6.4 34.3 9.9 5.9 23.8 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF106 PF01956.11 CDI82001.1 - 7.5 6.0 17.8 12 5.4 12.3 1.3 1 1 0 1 1 1 0 Integral membrane protein DUF106 PSK PF06404.7 CDI82001.1 - 7.6 7.3 15.7 24 5.7 7.8 2.5 2 1 0 2 2 2 0 Phytosulfokine precursor protein (PSK) DUF1764 PF08576.5 CDI82001.1 - 8 7.3 18.8 0.49 11.1 7.9 2.0 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF1764) DivIC PF04977.10 CDI82001.1 - 9.4 5.7 31.3 5.5 6.5 14.4 2.4 2 0 0 2 2 2 0 Septum formation initiator DUF4011 PF13195.1 CDI82001.1 - 9.8 6.1 12.4 13 5.7 8.6 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF4011) RskA PF10099.4 CDI82007.1 - 0.0052 16.5 7.8 0.0067 16.1 5.4 1.2 1 0 0 1 1 1 1 Anti-sigma-K factor rskA FimP PF09766.4 CDI82007.1 - 0.018 14.0 18.6 0.021 13.8 12.9 1.0 1 0 0 1 1 1 0 Fms-interacting protein ATHILA PF03078.10 CDI82007.1 - 0.089 11.3 5.0 0.093 11.2 3.5 1.0 1 0 0 1 1 1 0 ATHILA ORF-1 family Med15 PF09606.5 CDI82007.1 - 0.096 10.8 34.3 0.11 10.7 23.8 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Pex14_N PF04695.8 CDI82007.1 - 0.12 12.4 18.4 0.14 12.2 12.7 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Spt20 PF12090.3 CDI82007.1 - 0.14 11.5 10.9 0.17 11.2 7.5 1.3 1 0 0 1 1 1 0 Spt20 family CoA_transf_3 PF02515.12 CDI82007.1 - 0.14 11.3 8.1 0.15 11.2 5.6 1.0 1 0 0 1 1 1 0 CoA-transferase family III FNIP_N PF14636.1 CDI82007.1 - 0.2 12.1 13.3 0.24 11.8 9.2 1.1 1 0 0 1 1 1 0 Folliculin-interacting protein N-terminus Totivirus_coat PF05518.6 CDI82007.1 - 0.27 9.0 10.4 0.31 8.8 7.2 1.0 1 0 0 1 1 1 0 Totivirus coat protein MARCKS PF02063.12 CDI82007.1 - 0.3 10.8 17.5 0.33 10.7 12.1 1.0 1 0 0 1 1 1 0 MARCKS family DUF3408 PF11888.3 CDI82007.1 - 0.46 10.4 9.0 0.52 10.2 6.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) Suf PF05843.9 CDI82007.1 - 0.48 10.0 18.7 0.52 9.9 12.9 1.0 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) MelC1 PF06236.6 CDI82007.1 - 0.64 10.0 10.3 0.85 9.6 7.1 1.2 1 0 0 1 1 1 0 Tyrosinase co-factor MelC1 Peptidase_S15 PF02129.13 CDI82007.1 - 0.66 9.3 9.4 0.76 9.1 6.5 1.0 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) 2OG-FeII_Oxy_5 PF13759.1 CDI82007.1 - 0.75 10.1 4.8 1.1 9.6 3.3 1.3 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase PigN PF04987.9 CDI82007.1 - 0.98 7.9 3.6 1.2 7.7 2.5 1.1 1 0 0 1 1 1 0 Phosphatidylinositolglycan class N (PIG-N) DUF3729 PF12526.3 CDI82007.1 - 1 10.7 4.9 1.2 10.4 3.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3729) OMPdecase PF00215.19 CDI82007.1 - 1 8.7 7.6 1.1 8.5 5.3 1.1 1 0 0 1 1 1 0 Orotidine 5'-phosphate decarboxylase / HUMPS family OATP PF03137.15 CDI82007.1 - 1.2 7.0 6.8 1.2 7.0 4.7 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family DUF2232 PF09991.4 CDI82007.1 - 1.4 7.8 3.7 1.5 7.7 2.5 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) DUF4557 PF15101.1 CDI82007.1 - 1.4 8.7 20.9 1.7 8.4 14.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) R_equi_Vir PF05526.6 CDI82007.1 - 1.4 8.4 10.4 1.5 8.3 7.2 1.1 1 0 0 1 1 1 0 Rhodococcus equi virulence-associated protein Pex16 PF08610.5 CDI82007.1 - 1.6 7.6 8.7 1.7 7.5 6.0 1.1 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) Band_3_cyto PF07565.8 CDI82007.1 - 1.9 7.9 10.9 2 7.8 7.6 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Macoilin PF09726.4 CDI82007.1 - 1.9 6.6 15.0 2 6.6 10.4 1.0 1 0 0 1 1 1 0 Transmembrane protein Serinc PF03348.10 CDI82007.1 - 2.8 6.5 11.5 3 6.4 8.0 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) Pal1 PF08316.6 CDI82007.1 - 2.8 8.3 8.7 3.1 8.2 6.0 1.1 1 0 0 1 1 1 0 Pal1 cell morphology protein Zip PF02535.17 CDI82007.1 - 3 6.7 6.7 3.1 6.7 4.7 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Baculo_PP31 PF05311.6 CDI82007.1 - 3.1 7.0 11.5 3.4 6.8 8.0 1.1 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) Gag_spuma PF03276.9 CDI82007.1 - 3.1 6.0 21.6 3.5 5.8 14.9 1.0 1 0 0 1 1 1 0 Spumavirus gag protein Hid1 PF12722.2 CDI82007.1 - 3.3 5.2 10.4 3.2 5.3 7.2 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SelP_N PF04592.9 CDI82007.1 - 3.4 6.9 12.7 3.8 6.8 8.8 1.0 1 0 0 1 1 1 0 Selenoprotein P, N terminal region PAT1 PF09770.4 CDI82007.1 - 3.5 5.7 28.2 3.6 5.6 19.5 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SRP-alpha_N PF04086.8 CDI82007.1 - 3.6 6.8 13.5 4.1 6.7 9.3 1.0 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal FAM60A PF15396.1 CDI82007.1 - 3.6 7.2 11.7 3.9 7.1 8.1 1.1 1 0 0 1 1 1 0 Protein Family FAM60A Tim54 PF11711.3 CDI82007.1 - 3.7 6.0 8.7 4 5.9 6.0 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DivIC PF04977.10 CDI82007.1 - 3.8 7.0 15.4 6.4 6.3 10.7 1.4 1 0 0 1 1 1 0 Septum formation initiator UPF0560 PF10577.4 CDI82007.1 - 4.3 5.4 16.2 4.3 5.4 11.2 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Ribosomal_60s PF00428.14 CDI82007.1 - 4.5 7.7 14.3 7.5 7.0 9.9 1.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein vMSA PF00695.14 CDI82007.1 - 4.9 6.2 9.1 5.1 6.1 6.3 1.0 1 0 0 1 1 1 0 Major surface antigen from hepadnavirus Cellulose_synt PF03552.9 CDI82007.1 - 5.2 5.2 5.4 5.6 5.1 3.7 1.0 1 0 0 1 1 1 0 Cellulose synthase MSA-2c PF12238.3 CDI82007.1 - 5.7 6.5 17.5 4.2 6.9 11.2 1.4 1 1 1 2 2 2 0 Merozoite surface antigen 2c CDK5_activator PF03261.10 CDI82007.1 - 5.9 6.1 13.1 6.1 6.0 9.1 1.0 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein DUF3484 PF11983.3 CDI82007.1 - 6 7.7 19.3 9.1 7.1 13.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3484) Helicase_RecD PF05127.9 CDI82007.1 - 6.4 6.3 9.7 9.4 5.8 6.8 1.2 1 0 0 1 1 1 0 Helicase DUF4207 PF13904.1 CDI82007.1 - 6.6 6.0 24.2 7.3 5.8 16.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4207) Dala_Dala_lig_N PF01820.16 CDI82007.1 - 7 6.9 8.7 10 6.4 6.0 1.3 1 1 0 1 1 1 0 D-ala D-ala ligase N-terminus TFIIA PF03153.8 CDI82007.1 - 7.1 6.4 26.5 7.9 6.2 18.4 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit FLO_LFY PF01698.11 CDI82007.1 - 7.6 5.2 16.0 8.6 5.0 11.1 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein DUF913 PF06025.7 CDI82007.1 - 7.9 5.1 9.6 8.7 4.9 6.6 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) AUX_IAA PF02309.11 CDI82007.1 - 9.6 5.8 11.8 11 5.6 8.2 1.1 1 0 0 1 1 1 0 AUX/IAA family Rtf2 PF04641.7 CDI82007.1 - 9.6 5.3 16.3 11 5.1 11.3 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger Peptidase_U57 PF05582.7 CDI82007.1 - 9.8 5.0 9.2 10 4.9 6.4 1.0 1 0 0 1 1 1 0 YabG peptidase U57 Rtf2 PF04641.7 CDI82008.1 - 0.0082 15.3 6.2 0.0082 15.3 4.3 2.0 2 0 0 2 2 2 1 Rtf2 RING-finger Ycf1 PF05758.7 CDI82008.1 - 0.05 11.3 7.2 0.058 11.1 5.0 1.1 1 0 0 1 1 1 0 Ycf1 Zip PF02535.17 CDI82008.1 - 0.09 11.7 0.3 0.14 11.1 0.2 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter PAT1 PF09770.4 CDI82008.1 - 0.14 10.3 41.5 0.19 9.9 28.8 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 PBP1_TM PF14812.1 CDI82008.1 - 0.23 11.7 6.3 0.045 14.0 1.8 1.7 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal SOBP PF15279.1 CDI82008.1 - 0.28 11.5 13.4 0.38 11.0 9.3 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein SPX PF03105.14 CDI82008.1 - 0.33 10.6 15.9 0.46 10.2 11.0 1.3 1 0 0 1 1 1 0 SPX domain AAA_23 PF13476.1 CDI82008.1 - 0.51 10.6 18.8 0.84 9.9 13.1 1.3 1 0 0 1 1 1 0 AAA domain Hid1 PF12722.2 CDI82008.1 - 1.3 6.5 13.1 1.6 6.3 9.1 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Herpes_env PF01673.13 CDI82008.1 - 1.6 7.1 9.0 2.2 6.7 6.2 1.2 1 0 0 1 1 1 0 Herpesvirus putative major envelope glycoprotein Het-C PF07217.6 CDI82008.1 - 3.8 5.5 10.6 5 5.1 7.3 1.2 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C AP4E_app_platf PF14807.1 CDI82012.1 - 4.1e-09 36.6 0.0 1.2e-08 35.1 0.0 1.8 1 0 0 1 1 1 1 Adaptin AP4 complex epsilon appendage platform SR-25 PF10500.4 CDI82012.1 - 0.0024 17.3 16.4 0.18 11.2 6.1 2.5 2 0 0 2 2 2 2 Nuclear RNA-splicing-associated protein AMA-1 PF02430.10 CDI82023.1 - 2.9e-64 217.6 0.2 4.5e-64 217.0 0.1 1.2 1 0 0 1 1 1 1 Apical membrane antigen 1 YHS PF04945.8 CDI82023.1 - 0.00041 20.1 0.1 1.3 8.9 0.0 2.7 2 0 0 2 2 2 2 YHS domain DUF3508 PF12018.3 CDI82023.1 - 0.0033 16.4 1.0 0.55 9.1 0.0 3.1 3 0 0 3 3 3 2 Domain of unknown function (DUF3508) ADK PF00406.17 CDI82023.1 - 0.011 15.6 0.0 0.61 9.9 0.0 3.5 4 0 0 4 4 4 0 Adenylate kinase Lamp PF01299.12 CDI82023.1 - 3.8 6.5 3.7 8.7 5.3 0.0 2.6 2 0 0 2 2 2 0 Lysosome-associated membrane glycoprotein (Lamp) Rhabdo_ncap PF00945.13 CDI82023.1 - 7.1 5.1 1.7 19 3.7 1.2 1.6 1 0 0 1 1 1 0 Rhabdovirus nucleocapsid protein Spt20 PF12090.3 CDI82027.1 - 0.0073 15.6 0.6 0.0088 15.4 0.4 1.2 1 0 0 1 1 1 1 Spt20 family DUF4446 PF14584.1 CDI82027.1 - 0.0085 15.9 0.2 0.012 15.4 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4446) Med15 PF09606.5 CDI82027.1 - 0.016 13.4 31.0 0.019 13.1 21.5 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal PAT1 PF09770.4 CDI82027.1 - 5.7 5.0 25.6 7.2 4.7 17.7 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Suf PF05843.9 CDI82027.1 - 8.2 6.0 11.7 9.9 5.7 8.1 1.3 1 1 0 1 1 1 0 Suppressor of forked protein (Suf) CDC45 PF02724.9 CDI82029.1 - 0.19 9.7 39.5 0.23 9.4 27.4 1.4 1 0 0 1 1 1 0 CDC45-like protein U79_P34 PF03064.11 CDI82029.1 - 0.96 8.9 36.2 1.3 8.5 25.1 1.2 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Hid1 PF12722.2 CDI82029.1 - 8 3.9 48.0 9 3.8 33.2 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein PAP2 PF01569.16 CDI82031.1 - 0.0059 16.2 0.6 0.011 15.4 0.4 1.4 1 1 0 1 1 1 1 PAP2 superfamily DUF3995 PF13160.1 CDI82031.1 - 0.014 15.4 0.2 0.014 15.4 0.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3995) SARG PF15385.1 CDI82031.1 - 0.022 14.1 6.5 0.027 13.8 4.5 1.2 1 0 0 1 1 1 0 Specifically androgen-regulated gene protein DUF3801 PF12687.2 CDI82031.1 - 0.054 13.0 1.2 0.088 12.3 0.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3801) APC_CDC26 PF10471.4 CDI82031.1 - 0.56 10.9 11.5 4.2 8.1 0.7 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit 1 TFIIA PF03153.8 CDI82031.1 - 0.67 9.7 6.8 0.93 9.3 4.7 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4131 PF13567.1 CDI82031.1 - 1.3 8.3 8.8 0.27 10.6 3.4 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) Phostensin_N PF13916.1 CDI82031.1 - 2.3 8.2 10.7 6 6.9 1.7 2.4 2 0 0 2 2 2 0 PP1-regulatory protein, Phostensin N-terminal YppG PF14179.1 CDI82031.1 - 3.6 8.2 16.7 6.4 7.4 11.6 1.3 1 0 0 1 1 1 0 YppG-like protein Ribosomal_60s PF00428.14 CDI82031.1 - 4.5 7.7 11.1 0.48 10.8 3.7 2.1 2 0 0 2 2 2 0 60s Acidic ribosomal protein DUF4407 PF14362.1 CDI82031.1 - 9.3 5.1 8.5 20 4.0 5.9 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Nop14 PF04147.7 CDI82033.1 - 0.00095 17.2 10.7 0.0012 16.8 7.4 1.0 1 0 0 1 1 1 1 Nop14-like family CDC45 PF02724.9 CDI82033.1 - 0.017 13.2 2.9 0.019 12.9 2.0 1.1 1 0 0 1 1 1 0 CDC45-like protein Daxx PF03344.10 CDI82033.1 - 0.06 11.8 10.7 0.064 11.7 7.4 1.1 1 0 0 1 1 1 0 Daxx Family Ycf1 PF05758.7 CDI82033.1 - 0.095 10.4 1.8 0.1 10.2 1.3 1.2 1 0 0 1 1 1 0 Ycf1 Mito_fiss_reg PF05308.6 CDI82033.1 - 0.11 11.8 6.8 0.15 11.3 4.7 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator DUF2890 PF11081.3 CDI82033.1 - 0.53 10.3 15.0 0.83 9.6 10.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) CAP_N PF01213.14 CDI82033.1 - 0.8 8.9 11.3 1.2 8.3 7.9 1.4 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Prothymosin PF03247.9 CDI82033.1 - 1.4 9.1 33.9 2.7 8.1 23.5 1.4 1 0 0 1 1 1 0 Prothymosin/parathymosin family Paf1 PF03985.8 CDI82033.1 - 3.6 6.2 19.8 4.8 5.8 13.8 1.1 1 0 0 1 1 1 0 Paf1 DUF605 PF04652.11 CDI82033.1 - 9.3 5.5 13.2 13 5.0 9.1 1.2 1 0 0 1 1 1 0 Vta1 like AIF_C PF14721.1 CDI82034.1 - 0.02 15.1 6.2 0.023 14.9 4.3 1.0 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Rxt3 PF08642.5 CDI82034.1 - 0.14 12.4 0.1 0.16 12.1 0.0 1.2 1 0 0 1 1 1 0 Histone deacetylation protein Rxt3 TRAP_alpha PF03896.11 CDI82034.1 - 0.17 10.8 17.7 0.19 10.7 12.3 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Sigma70_ner PF04546.8 CDI82034.1 - 0.18 11.4 22.4 0.21 11.2 15.5 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region BUD22 PF09073.5 CDI82034.1 - 0.21 10.6 20.1 0.24 10.4 13.9 1.1 1 0 0 1 1 1 0 BUD22 Raftlin PF15250.1 CDI82034.1 - 0.27 9.7 6.3 0.29 9.6 4.4 1.0 1 0 0 1 1 1 0 Raftlin CobT PF06213.7 CDI82034.1 - 0.33 10.0 26.8 0.33 10.0 18.6 1.0 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT YqfQ PF14181.1 CDI82034.1 - 0.33 10.9 17.5 0.38 10.7 12.1 1.0 1 0 0 1 1 1 0 YqfQ-like protein Serinc PF03348.10 CDI82034.1 - 0.42 9.2 4.1 0.43 9.2 2.9 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) FHIPEP PF00771.15 CDI82034.1 - 0.49 8.6 4.2 0.54 8.5 2.9 1.1 1 0 0 1 1 1 0 FHIPEP family CPSF100_C PF13299.1 CDI82034.1 - 0.52 10.4 6.9 0.54 10.4 4.8 1.1 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal SpoIIIAH PF12685.2 CDI82034.1 - 0.56 9.6 13.6 0.68 9.3 9.5 1.0 1 0 0 1 1 1 0 SpoIIIAH-like protein Eapp_C PF10238.4 CDI82034.1 - 0.58 10.0 4.3 0.69 9.8 2.9 1.2 1 0 0 1 1 1 0 E2F-associated phosphoprotein DUF2052 PF09747.4 CDI82034.1 - 0.63 9.9 24.1 0.7 9.7 16.7 1.0 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) DDHD PF02862.12 CDI82034.1 - 0.71 9.6 11.8 0.8 9.4 8.2 1.0 1 0 0 1 1 1 0 DDHD domain DUF1510 PF07423.6 CDI82034.1 - 0.82 8.9 24.0 0.94 8.7 16.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DUF913 PF06025.7 CDI82034.1 - 0.99 8.0 5.2 1.1 7.9 3.6 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Bud13 PF09736.4 CDI82034.1 - 1 9.6 13.4 1.1 9.4 9.3 1.1 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex NPR3 PF03666.8 CDI82034.1 - 1 7.8 7.2 1 7.7 5.0 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 FLO_LFY PF01698.11 CDI82034.1 - 1.1 8.0 7.4 1.2 7.8 5.1 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein DHHW PF14286.1 CDI82034.1 - 1.2 8.4 7.6 1.1 8.4 5.3 1.0 1 0 0 1 1 1 0 DHHW protein Zip PF02535.17 CDI82034.1 - 1.2 8.0 8.5 1.3 7.9 5.9 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter CENP-T PF15511.1 CDI82034.1 - 1.5 8.0 16.8 1.7 7.7 11.7 1.0 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T CDC45 PF02724.9 CDI82034.1 - 1.6 6.6 19.5 1.8 6.5 13.5 1.0 1 0 0 1 1 1 0 CDC45-like protein Glyco_transf_15 PF01793.11 CDI82034.1 - 1.6 7.5 6.3 1.9 7.3 4.4 1.0 1 0 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase Vfa1 PF08432.5 CDI82034.1 - 2 8.3 17.8 2.4 8.1 12.3 1.0 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF3824 PF12868.2 CDI82034.1 - 2.1 9.2 6.2 2.5 9.0 4.3 1.1 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) Tim54 PF11711.3 CDI82034.1 - 2.4 6.6 13.7 2.7 6.5 9.5 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 FemAB PF02388.11 CDI82034.1 - 2.5 6.6 8.6 3 6.4 5.9 1.0 1 0 0 1 1 1 0 FemAB family DUF4246 PF14033.1 CDI82034.1 - 2.6 6.5 9.8 2.8 6.4 6.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4246) ADP_ribosyl_GH PF03747.9 CDI82034.1 - 2.6 7.7 5.3 2.7 7.6 3.7 1.0 1 0 0 1 1 1 0 ADP-ribosylglycohydrolase EIIBC-GUT_N PF03612.9 CDI82034.1 - 2.7 7.5 4.5 3.3 7.2 3.1 1.2 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Fmp27_WPPW PF10359.4 CDI82034.1 - 2.7 6.2 8.9 2.9 6.2 6.2 1.0 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Tom37_C PF11801.3 CDI82034.1 - 2.8 7.7 9.8 3.7 7.3 6.8 1.2 1 0 0 1 1 1 0 Tom37 C-terminal domain CKAP2_C PF15297.1 CDI82034.1 - 2.9 6.6 13.9 3.2 6.4 9.6 1.0 1 0 0 1 1 1 0 Cytoskeleton-associated protein 2 C-terminus SpoIIP PF07454.6 CDI82034.1 - 3.3 6.8 10.7 3.6 6.6 7.4 1.0 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) FYDLN_acid PF09538.5 CDI82034.1 - 3.5 8.2 20.6 4.3 7.9 14.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) DUF4628 PF15429.1 CDI82034.1 - 3.7 6.8 11.9 4.2 6.7 8.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4628) G-alpha PF00503.15 CDI82034.1 - 3.8 6.0 9.3 3.9 6.0 6.4 1.0 1 0 0 1 1 1 0 G-protein alpha subunit SAPS PF04499.10 CDI82034.1 - 5.3 5.5 11.3 5.7 5.4 7.9 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein ECIST_Cterm PF14784.1 CDI82034.1 - 5.3 7.0 6.9 7.7 6.4 4.8 1.3 1 0 0 1 1 1 0 C-terminal domain of the ECSIT protein DUF2722 PF10846.3 CDI82034.1 - 5.5 5.9 9.9 6 5.7 6.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Sec62 PF03839.11 CDI82034.1 - 5.7 6.2 8.7 6.5 6.1 6.0 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 DUF4011 PF13195.1 CDI82034.1 - 5.7 6.9 10.1 6.7 6.6 7.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4011) SHR3_chaperone PF08229.6 CDI82034.1 - 5.8 5.8 11.5 8.1 5.3 7.9 1.3 1 1 0 1 1 1 0 ER membrane protein SH3 TraH_2 PF06871.6 CDI82034.1 - 5.9 6.2 8.0 6.8 6.0 5.6 1.1 1 0 0 1 1 1 0 TraH_2 RR_TM4-6 PF06459.7 CDI82034.1 - 6.2 6.6 21.8 7.3 6.3 15.1 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DDRGK PF09756.4 CDI82034.1 - 6.2 6.1 29.2 7.5 5.9 20.2 1.1 1 0 0 1 1 1 0 DDRGK domain Kei1 PF08552.6 CDI82034.1 - 6.3 6.4 6.2 7.1 6.2 4.3 1.0 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 Rtf2 PF04641.7 CDI82034.1 - 6.9 5.7 11.1 7.8 5.6 7.7 1.0 1 0 0 1 1 1 0 Rtf2 RING-finger SprA-related PF12118.3 CDI82034.1 - 7.1 5.8 18.7 8.3 5.6 13.0 1.0 1 0 0 1 1 1 0 SprA-related family Pox_Ag35 PF03286.9 CDI82034.1 - 7.1 6.1 21.2 8.8 5.7 14.7 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein POX PF07526.6 CDI82034.1 - 7.1 6.8 8.6 8.4 6.6 5.9 1.0 1 0 0 1 1 1 0 Associated with HOX SID-1_RNA_chan PF13965.1 CDI82034.1 - 8.4 4.4 6.2 8.9 4.3 4.3 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 RED_N PF07808.8 CDI82043.1 - 9.3e-05 21.7 2.2 9.3e-05 21.7 1.5 2.1 2 0 0 2 2 2 1 RED-like protein N-terminal region FlxA PF14282.1 CDI82043.1 - 0.00037 20.3 20.8 0.00037 20.3 14.4 2.3 2 0 0 2 2 2 1 FlxA-like protein HOOK PF05622.7 CDI82043.1 - 0.0012 16.8 6.7 0.0012 16.8 4.6 2.0 2 0 0 2 2 2 1 HOOK protein DUF607 PF04678.8 CDI82043.1 - 0.38 10.6 10.7 0.11 12.4 4.6 1.9 2 0 0 2 2 2 0 Protein of unknown function, DUF607 Activator_LAG-3 PF11498.3 CDI82043.1 - 0.43 9.2 40.1 0.0098 14.6 9.7 2.2 2 0 0 2 2 2 0 Transcriptional activator LAG-3 Herpes_UL87 PF03043.9 CDI82043.1 - 1.7 6.9 4.3 2.3 6.4 3.0 1.3 1 1 0 1 1 1 0 Herpesvirus UL87 family DUF4355 PF14265.1 CDI82043.1 - 2.7 7.9 22.9 0.084 12.8 7.9 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4355) Suf PF05843.9 CDI82043.1 - 3.4 7.3 10.2 1.5 8.5 3.4 2.0 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) DUF3371 PF11851.3 CDI82043.1 - 4.3 8.0 17.7 2.2 8.9 3.6 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3371) SprA-related PF12118.3 CDI82045.1 - 3.7e-05 23.1 57.6 4.5e-05 22.9 39.9 1.0 1 0 0 1 1 1 1 SprA-related family CAF-1_p150 PF11600.3 CDI82045.1 - 0.00024 20.5 38.8 0.00036 19.9 26.9 1.3 1 0 0 1 1 1 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal Nop53 PF07767.6 CDI82045.1 - 1.2 8.0 32.2 1.5 7.7 22.3 1.0 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) UPF0564 PF10595.4 CDI82045.1 - 1.8 7.4 40.6 2 7.2 28.1 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0564 TFIIA PF03153.8 CDI82045.1 - 2 8.2 55.5 2.4 7.9 38.4 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Med15 PF09606.5 CDI82045.1 - 2.6 6.1 61.3 3.3 5.7 42.5 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal RR_TM4-6 PF06459.7 CDI82045.1 - 4.1 7.2 27.5 5.2 6.8 19.1 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 AAA_23 PF13476.1 CDI82045.1 - 4.4 7.5 25.8 5.7 7.2 17.9 1.1 1 0 0 1 1 1 0 AAA domain RAP1 PF07218.6 CDI82045.1 - 5.3 5.0 17.2 6.5 4.7 11.9 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DUF3337 PF11816.3 CDI82045.1 - 5.4 6.3 34.9 6.9 5.9 24.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3337) SOBP PF15279.1 CDI82045.1 - 7.1 6.9 39.5 8.4 6.6 27.4 1.0 1 0 0 1 1 1 0 Sine oculis-binding protein CDC27 PF09507.5 CDI82045.1 - 8.9 5.4 36.7 11 5.1 25.4 1.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Calici_coat PF00915.15 CDI82049.1 - 5.5 5.8 8.3 6 5.6 5.7 1.1 1 0 0 1 1 1 0 Calicivirus coat protein MIP-T3 PF10243.4 CDI82054.1 - 0.71 8.2 33.8 0.78 8.1 23.4 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DUF1510 PF07423.6 CDI82054.1 - 1.5 8.1 26.9 1.8 7.9 18.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) GAGA_bind PF06217.7 CDI82054.1 - 1.5 8.6 32.2 1.7 8.5 22.3 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family DUF4175 PF13779.1 CDI82054.1 - 1.9 6.0 63.3 2.2 5.8 43.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) DUF4045 PF13254.1 CDI82054.1 - 2 7.6 32.8 2.4 7.3 22.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) CDC45 PF02724.9 CDI82054.1 - 2.2 6.2 23.8 2.5 6.0 16.5 1.0 1 0 0 1 1 1 0 CDC45-like protein Cellulose_synt PF03552.9 CDI82054.1 - 2.5 6.2 10.1 2.7 6.1 7.0 1.1 1 0 0 1 1 1 0 Cellulose synthase Raftlin PF15250.1 CDI82054.1 - 3.2 6.1 25.8 3.7 5.9 17.9 1.2 1 0 0 1 1 1 0 Raftlin Ribosomal_60s PF00428.14 CDI82054.1 - 5.4 7.4 17.8 1.9 8.9 4.7 2.2 2 0 0 2 2 2 0 60s Acidic ribosomal protein NARP1 PF12569.3 CDI82054.1 - 6.3 5.4 28.1 8 5.0 19.5 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Peptidase_S15 PF02129.13 CDI82054.1 - 6.6 6.0 24.0 8.1 5.7 16.7 1.2 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) DUF3123 PF11321.3 CDI82054.1 - 7.4 6.8 14.6 1 9.6 4.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3123) FLO_LFY PF01698.11 CDI82054.1 - 8.1 5.1 26.4 10 4.8 18.3 1.2 1 0 0 1 1 1 0 Floricaula / Leafy protein SAGA-Tad1 PF12767.2 CDI82054.1 - 8.4 5.9 33.6 9.9 5.7 23.3 1.1 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit UPF0564 PF10595.4 CDI82056.1 - 7.3e-05 21.8 14.8 7.3e-05 21.8 10.3 3.2 2 1 1 3 3 3 1 Uncharacterised protein family UPF0564 CAF-1_p150 PF11600.3 CDI82056.1 - 0.0014 18.1 26.2 0.0014 18.1 18.2 3.4 2 1 1 3 3 3 2 Chromatin assembly factor 1 complex p150 subunit, N-terminal Utp14 PF04615.8 CDI82056.1 - 0.071 11.2 75.5 0.088 10.9 31.5 2.2 2 0 0 2 2 2 0 Utp14 protein MAP7 PF05672.6 CDI82056.1 - 0.074 12.4 80.8 0.21 10.9 28.9 2.2 2 0 0 2 2 2 0 MAP7 (E-MAP-115) family MIP-T3 PF10243.4 CDI82059.1 - 1 7.7 112.4 1.3 7.4 77.9 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DUF1184 PF06683.6 CDI82062.1 - 0.11 12.1 0.1 0.23 11.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1184) TPR_2 PF07719.12 CDI82063.1 - 0.14 12.1 0.3 0.37 10.8 0.2 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF972 PF06156.8 CDI82065.1 - 0.01 16.1 11.2 0.52 10.6 1.8 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF972) DUF2353 PF09789.4 CDI82065.1 - 0.029 13.6 11.2 0.035 13.3 7.5 1.3 1 1 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) DUF837 PF05769.6 CDI82065.1 - 0.068 12.6 8.4 0.12 11.8 1.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF837) Spc7 PF08317.6 CDI82065.1 - 0.093 11.3 12.1 0.14 10.8 8.4 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein APG6 PF04111.7 CDI82065.1 - 0.099 11.6 14.9 0.13 11.2 10.3 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 CAF-1_p150 PF11600.3 CDI82065.1 - 0.21 10.9 9.8 0.39 10.0 6.8 1.5 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal KaiC PF06745.8 CDI82065.1 - 0.7 8.9 3.3 4.9 6.2 0.7 2.0 1 1 1 2 2 2 0 KaiC GAS PF13851.1 CDI82065.1 - 1.1 8.4 14.3 1.9 7.6 9.2 1.9 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF1003 PF06210.6 CDI82065.1 - 1.5 8.8 8.6 3.8 7.4 0.5 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1003) HALZ PF02183.13 CDI82065.1 - 2 8.1 11.5 3 7.6 1.2 2.6 2 0 0 2 2 2 0 Homeobox associated leucine zipper CtIP_N PF10482.4 CDI82065.1 - 2.5 7.9 13.4 3.8 7.3 9.3 1.3 1 0 0 1 1 1 0 Tumour-suppressor protein CtIP N-terminal domain Mod_r PF07200.8 CDI82065.1 - 2.5 7.9 16.2 0.24 11.3 3.8 2.2 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein FlaC_arch PF05377.6 CDI82065.1 - 3.3 7.6 5.3 2.4 8.1 0.1 2.5 3 0 0 3 3 2 0 Flagella accessory protein C (FlaC) bZIP_1 PF00170.16 CDI82065.1 - 5.5 7.0 18.0 0.59 10.1 0.7 3.6 1 1 1 3 3 3 0 bZIP transcription factor FimP PF09766.4 CDI82067.1 - 0.0013 17.8 26.7 0.023 13.7 8.7 2.1 2 0 0 2 2 2 2 Fms-interacting protein Spt20 PF12090.3 CDI82067.1 - 0.0016 17.8 16.6 0.032 13.5 3.3 2.2 2 0 0 2 2 2 2 Spt20 family CAF-1_p150 PF11600.3 CDI82067.1 - 0.062 12.6 15.6 0.4 10.0 5.3 2.2 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal SR-25 PF10500.4 CDI82067.1 - 0.066 12.6 25.4 0.025 14.0 5.8 2.1 1 1 1 2 2 2 0 Nuclear RNA-splicing-associated protein DUF4207 PF13904.1 CDI82067.1 - 0.072 12.4 33.3 0.57 9.5 10.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4207) 60KD_IMP PF02096.15 CDI82067.1 - 0.15 11.6 12.7 0.18 11.4 2.3 2.3 2 0 0 2 2 2 0 60Kd inner membrane protein DUF3371 PF11851.3 CDI82067.1 - 0.17 12.5 27.9 0.16 12.6 3.9 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3371) IPP-2 PF04979.9 CDI82067.1 - 0.32 11.2 8.7 0.32 11.2 1.5 2.4 2 0 0 2 2 2 0 Protein phosphatase inhibitor 2 (IPP-2) AAA_23 PF13476.1 CDI82067.1 - 0.55 10.5 13.3 0.4 10.9 2.4 2.0 2 0 0 2 2 2 0 AAA domain zf-DHHC PF01529.15 CDI82067.1 - 0.65 9.3 7.7 0.57 9.5 0.2 2.1 2 0 0 2 2 2 0 DHHC palmitoyltransferase DUF3801 PF12687.2 CDI82067.1 - 0.71 9.4 15.9 0.28 10.7 2.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3801) DUF4064 PF13273.1 CDI82067.1 - 0.77 9.8 2.5 9.7 6.3 0.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) OATP PF03137.15 CDI82067.1 - 0.95 7.4 13.1 0.22 9.5 3.2 2.1 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family EphA2_TM PF14575.1 CDI82067.1 - 1.6 9.1 11.0 0.86 10.0 1.0 2.5 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain SelP_N PF04592.9 CDI82067.1 - 1.7 7.9 13.2 1.2 8.4 3.6 2.1 2 0 0 2 2 2 0 Selenoprotein P, N terminal region CD20 PF04103.10 CDI82067.1 - 2 8.2 13.6 5.9 6.8 3.7 2.6 1 1 1 2 2 2 0 CD20-like family Ndc1_Nup PF09531.5 CDI82067.1 - 2.6 6.3 19.4 3.7 5.8 13.4 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF1632 PF07857.7 CDI82067.1 - 3.1 6.9 5.2 0.68 9.1 0.9 1.8 2 0 0 2 2 2 0 CEO family (DUF1632) TMEM223 PF14640.1 CDI82067.1 - 3.4 7.5 7.5 5.5 6.8 1.1 2.2 2 0 0 2 2 2 0 Transmembrane protein 223 Rxt3 PF08642.5 CDI82067.1 - 4.8 7.4 8.5 6.7 6.9 1.3 2.4 2 0 0 2 2 2 0 Histone deacetylation protein Rxt3 Suf PF05843.9 CDI82067.1 - 5.1 6.7 41.3 0.31 10.7 12.9 2.0 1 1 1 2 2 2 0 Suppressor of forked protein (Suf) MAT1 PF06391.8 CDI82067.1 - 6.6 6.2 21.2 3.6 7.1 1.9 2.1 2 0 0 2 2 2 0 CDK-activating kinase assembly factor MAT1 DUF3381 PF11861.3 CDI82067.1 - 8.2 5.9 13.3 12 5.4 4.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3381) Utp14 PF04615.8 CDI82067.1 - 9.9 4.1 25.1 14 3.6 17.4 1.2 1 0 0 1 1 1 0 Utp14 protein HC2 PF07382.6 CDI82068.1 - 6.7e-05 22.8 15.8 6.7e-05 22.8 11.0 2.4 2 0 0 2 2 2 1 Histone H1-like nucleoprotein HC2 SR-25 PF10500.4 CDI82069.1 - 7.7e-05 22.2 12.2 7.7e-05 22.2 8.4 1.5 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein DUF4614 PF15391.1 CDI82069.1 - 0.2 11.4 13.0 0.029 14.1 6.3 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4614) Adaptin_binding PF10199.4 CDI82069.1 - 0.24 11.7 4.7 3.1 8.1 3.2 2.2 1 1 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 DUF605 PF04652.11 CDI82069.1 - 2.1 7.6 35.1 2.5 7.4 24.3 1.1 1 0 0 1 1 1 0 Vta1 like Corona_nucleoca PF00937.13 CDI82069.1 - 4.7 6.0 12.2 7.5 5.3 8.4 1.3 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein Macoilin PF09726.4 CDI82069.1 - 5.9 5.0 13.7 9.7 4.3 9.5 1.3 1 0 0 1 1 1 0 Transmembrane protein UPF0565 PF10561.4 CDI82071.1 - 0.03 13.2 1.5 0.038 12.9 1.1 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0565 Ant_C PF05586.6 CDI82071.1 - 0.63 10.5 9.2 0.46 10.9 1.8 2.0 2 0 0 2 2 2 0 Anthrax receptor C-terminus region DUF4647 PF15504.1 CDI82071.1 - 0.88 8.3 18.7 0.92 8.2 13.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4647) Pan_kinase PF03309.9 CDI82071.1 - 3.2 7.2 6.0 3.7 6.9 4.2 1.1 1 0 0 1 1 1 0 Type III pantothenate kinase ATG22 PF11700.3 CDI82071.1 - 4.2 5.7 8.7 0.49 8.8 0.1 2.0 1 1 1 2 2 2 0 Vacuole effluxer Atg22 like DUF445 PF04286.7 CDI82072.1 - 0.0033 17.0 2.0 0.0061 16.1 1.4 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF445) CBFD_NFYB_HMF PF00808.18 CDI82072.1 - 0.7 10.0 14.9 1.8e+03 -0.9 10.3 2.7 1 1 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Activator_LAG-3 PF11498.3 CDI82102.1 - 0.00014 20.7 10.2 0.00014 20.7 7.1 16.9 6 4 10 17 17 17 1 Transcriptional activator LAG-3 SPX PF03105.14 CDI82104.1 - 0.0053 16.5 3.5 0.0053 16.5 2.4 2.6 2 1 0 2 2 1 1 SPX domain DUF1183 PF06682.7 CDI82104.1 - 0.0077 15.8 2.3 0.0077 15.8 1.6 3.5 3 1 1 4 4 3 1 Protein of unknown function (DUF1183) DUF3357 PF11837.3 CDI82104.1 - 0.019 14.8 0.6 0.019 14.8 0.4 5.4 5 1 2 7 7 7 0 Domain of unknown function (DUF3357) WD40 PF00400.27 CDI82104.1 - 0.029 14.2 1.0 8.6 6.4 0.3 2.7 2 0 0 2 2 2 0 WD domain, G-beta repeat DUF3753 PF12575.3 CDI82104.1 - 0.18 11.6 0.1 0.6 9.9 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3753) ODV-E18 PF10717.4 CDI82104.1 - 0.74 9.2 0.0 0.74 9.2 0.0 3.0 3 0 0 3 3 3 0 Occlusion-derived virus envelope protein ODV-E18 SID-1_RNA_chan PF13965.1 CDI82104.1 - 0.76 7.8 14.2 0.066 11.3 2.8 2.1 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 7TM_GPCR_Sru PF10322.4 CDI82104.1 - 0.96 8.4 1.5 1.6 7.7 0.0 2.0 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Sru DUF3899 PF13038.1 CDI82104.1 - 1.7 8.8 5.4 7.3 6.8 0.0 3.6 3 1 0 3 3 3 0 Domain of unknown function (DUF3899) HlyD_2 PF12700.2 CDI82104.1 - 1.9 7.5 19.6 0.97 8.5 1.1 2.4 2 0 0 2 2 2 0 HlyD family secretion protein DUF912 PF06024.7 CDI82104.1 - 3.7 7.6 25.4 0.043 13.8 1.9 5.0 3 1 1 4 4 3 0 Nucleopolyhedrovirus protein of unknown function (DUF912) RRM_1 PF00076.17 CDI82105.1 - 1.9e-16 59.4 0.0 3.2e-16 58.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CDI82105.1 - 1.3e-12 47.4 0.0 2.4e-12 46.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CDI82105.1 - 3e-09 36.5 0.1 5.5e-09 35.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AAA_23 PF13476.1 CDI82105.1 - 0.0098 16.2 7.5 0.012 15.9 5.2 1.2 1 0 0 1 1 1 1 AAA domain His_Phos_2 PF00328.17 CDI82105.1 - 0.34 10.2 8.9 0.42 9.8 6.2 1.3 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 2) Med15 PF09606.5 CDI82105.1 - 1.2 7.2 56.5 1.6 6.8 39.2 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal PAT1 PF09770.4 CDI82105.1 - 1.2 7.2 36.0 1.3 7.1 25.0 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 UPF0561 PF10573.4 CDI82108.1 - 1 9.2 14.3 2.2 8.1 3.5 2.1 1 1 1 2 2 2 0 Uncharacterised protein family UPF0561 SR-25 PF10500.4 CDI82113.1 - 0.58 9.6 20.1 0.032 13.6 10.0 1.8 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Ycf1 PF05758.7 CDI82119.1 - 0.27 8.9 5.6 0.43 8.2 3.9 1.3 1 0 0 1 1 1 0 Ycf1 Trypan_PARP PF05887.6 CDI82127.1 - 0.00062 19.6 20.2 0.00062 19.6 14.0 2.1 1 1 1 2 2 2 1 Procyclic acidic repetitive protein (PARP) MIP-T3 PF10243.4 CDI82127.1 - 0.0029 16.1 55.7 0.0032 16.0 38.6 1.1 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 DUF1777 PF08648.7 CDI82127.1 - 7 6.3 90.7 2.1e+03 -1.8 62.9 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1777) DUF4557 PF15101.1 CDI82130.1 - 0.0013 18.5 10.3 0.0013 18.5 7.1 3.5 3 0 0 3 3 3 1 Domain of unknown function (DUF4557) Utp14 PF04615.8 CDI82130.1 - 0.28 9.3 26.6 0.066 11.3 4.2 2.3 2 0 0 2 2 2 0 Utp14 protein FimP PF09766.4 CDI82130.1 - 8.6 5.3 32.6 0.042 12.9 11.9 2.2 2 0 0 2 2 2 0 Fms-interacting protein SpoIISB_antitox PF14185.1 CDI82132.1 - 0.015 15.0 0.0 4.6 7.0 0.0 2.4 2 0 0 2 2 2 0 Antitoxin SpoIISB, type II toxin-antitoxin system YebO PF13974.1 CDI82133.1 - 0.61 9.9 0.0 0.61 9.9 0.0 8.2 4 3 2 6 6 6 0 YebO-like protein Utp14 PF04615.8 CDI82157.1 - 1.2 7.1 70.3 1.6 6.8 48.7 1.1 1 0 0 1 1 1 0 Utp14 protein Herpes_UL87 PF03043.9 CDI82157.1 - 1.4 7.1 34.0 2 6.7 23.6 1.4 1 0 0 1 1 1 0 Herpesvirus UL87 family DUF4658 PF15555.1 CDI82158.1 - 0.00046 20.0 1.7 0.00076 19.3 1.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4658) Merozoite_SPAM PF07133.6 CDI82158.1 - 0.021 14.6 17.9 0.027 14.3 12.4 1.1 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) Pox_Ag35 PF03286.9 CDI82158.1 - 0.033 13.7 14.9 0.041 13.4 10.3 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DUF2890 PF11081.3 CDI82158.1 - 0.043 13.8 15.6 0.049 13.6 10.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) ESX-1_EspG PF14011.1 CDI82158.1 - 0.052 12.8 4.1 0.06 12.5 2.8 1.1 1 0 0 1 1 1 0 EspG family Gly-zipper_OmpA PF13436.1 CDI82158.1 - 0.12 12.0 9.9 0.18 11.4 6.9 1.3 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain CDC27 PF09507.5 CDI82158.1 - 0.15 11.2 19.6 0.19 10.8 13.6 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 DUF605 PF04652.11 CDI82158.1 - 0.37 10.1 19.6 0.43 9.9 13.6 1.2 1 0 0 1 1 1 0 Vta1 like Suf PF05843.9 CDI82158.1 - 0.47 10.1 24.5 0.57 9.8 17.0 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF4569 PF15133.1 CDI82158.1 - 0.52 9.6 15.8 0.62 9.4 10.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4569) DUF4551 PF15087.1 CDI82158.1 - 0.69 8.2 15.9 0.79 8.0 11.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Pex14_N PF04695.8 CDI82158.1 - 0.84 9.6 23.3 1.2 9.2 15.9 1.4 1 1 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF3708 PF12501.3 CDI82158.1 - 1.1 9.1 3.7 1.3 8.8 2.6 1.2 1 0 0 1 1 1 0 Phosphate ATP-binding cassette transporter Menin PF05053.8 CDI82158.1 - 1.4 7.0 10.7 1.6 6.8 7.4 1.1 1 0 0 1 1 1 0 Menin PAT1 PF09770.4 CDI82158.1 - 1.6 6.8 33.9 1.8 6.6 23.5 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF572 PF04502.8 CDI82158.1 - 1.9 7.6 21.3 2.1 7.4 14.8 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF572) Lin-8 PF03353.10 CDI82158.1 - 1.9 7.6 21.3 2.3 7.4 14.8 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist UPF0560 PF10577.4 CDI82158.1 - 2.3 6.3 18.1 2.6 6.2 12.5 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 DUF966 PF06136.8 CDI82158.1 - 2.3 7.5 16.9 2.8 7.2 11.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF966) AvrE PF11725.3 CDI82158.1 - 2.8 4.8 21.3 3 4.7 14.8 1.0 1 0 0 1 1 1 0 Pathogenicity factor Band_3_cyto PF07565.8 CDI82158.1 - 3.7 6.9 14.7 4.3 6.7 10.2 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain FLO_LFY PF01698.11 CDI82158.1 - 4 6.1 19.1 5 5.8 13.2 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein SAPS PF04499.10 CDI82158.1 - 4.2 5.9 14.8 5 5.6 10.3 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Macoilin PF09726.4 CDI82158.1 - 4.4 5.4 15.2 5.4 5.1 10.5 1.2 1 0 0 1 1 1 0 Transmembrane protein DUF2228 PF10228.4 CDI82158.1 - 4.5 6.7 8.9 5.6 6.4 6.2 1.1 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2228) PsbW PF07123.7 CDI82158.1 - 5.6 7.0 7.9 8 6.5 5.5 1.3 1 0 0 1 1 1 0 Photosystem II reaction centre W protein (PsbW) Otopetrin PF03189.8 CDI82158.1 - 5.7 5.8 7.8 6.1 5.7 5.4 1.2 1 0 0 1 1 1 0 Otopetrin Neur_chan_memb PF02932.11 CDI82158.1 - 5.9 6.7 11.3 7.4 6.3 7.9 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Glyco_hydro_63 PF03200.11 CDI82158.1 - 6.1 4.5 12.0 6.5 4.4 8.3 1.0 1 0 0 1 1 1 0 Mannosyl oligosaccharide glucosidase GAGA_bind PF06217.7 CDI82158.1 - 6.5 6.6 18.6 7.8 6.3 12.9 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family SprA-related PF12118.3 CDI82158.1 - 6.6 5.9 34.7 8.5 5.6 24.1 1.2 1 0 0 1 1 1 0 SprA-related family BTV_NS2 PF04514.7 CDI82158.1 - 6.9 5.4 16.1 7.5 5.3 11.2 1.0 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 RR_TM4-6 PF06459.7 CDI82158.1 - 7 6.4 23.7 8.4 6.1 16.4 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Peptidase_S64 PF08192.6 CDI82158.1 - 7.4 4.7 12.3 8.5 4.5 8.5 1.2 1 0 0 1 1 1 0 Peptidase family S64 Med15 PF09606.5 CDI82158.1 - 8.1 4.5 40.8 8.8 4.3 28.3 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal VID27 PF08553.5 CDI82158.1 - 8.4 4.4 14.6 9.5 4.2 10.1 1.1 1 0 0 1 1 1 0 VID27 cytoplasmic protein NARP1 PF12569.3 CDI82158.1 - 9.6 4.8 19.9 11 4.5 13.8 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DNA_pol_viral_N PF00242.12 CDI82158.1 - 9.8 5.0 17.3 12 4.8 12.0 1.0 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain Daxx PF03344.10 CDI82162.1 - 0.0051 15.3 34.6 0.0059 15.1 24.0 1.1 1 0 0 1 1 1 1 Daxx Family MIP-T3 PF10243.4 CDI82162.1 - 0.006 15.1 39.8 0.0069 14.9 27.6 1.1 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 Ycf1 PF05758.7 CDI82162.1 - 0.3 8.7 26.5 0.37 8.4 18.4 1.2 1 0 0 1 1 1 0 Ycf1 Utp14 PF04615.8 CDI82162.1 - 0.49 8.4 41.7 0.63 8.1 28.9 1.1 1 0 0 1 1 1 0 Utp14 protein PLRV_ORF5 PF01690.12 CDI82162.1 - 0.55 9.3 34.0 0.74 8.8 23.5 1.2 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein LMBR1 PF04791.11 CDI82162.1 - 0.56 8.7 15.9 0.66 8.4 11.0 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Macoilin PF09726.4 CDI82162.1 - 0.63 8.2 38.3 0.77 7.9 26.5 1.1 1 0 0 1 1 1 0 Transmembrane protein TFIIF_alpha PF05793.7 CDI82162.1 - 0.69 8.2 28.1 0.95 7.7 19.5 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF572 PF04502.8 CDI82162.1 - 1.4 8.0 41.1 1.9 7.6 28.5 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) eIF-3_zeta PF05091.7 CDI82162.1 - 1.8 7.0 31.2 2.3 6.7 21.6 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) PAT1 PF09770.4 CDI82162.1 - 4.3 5.4 69.7 5.4 5.1 48.3 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 RR_TM4-6 PF06459.7 CDI82163.1 - 0.0033 17.3 17.8 0.0038 17.1 12.4 1.1 1 0 0 1 1 1 1 Ryanodine Receptor TM 4-6 Med15 PF09606.5 CDI82163.1 - 0.0045 15.2 65.9 0.0054 15.0 45.7 1.0 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal Ycf1 PF05758.7 CDI82163.1 - 0.013 13.3 12.8 0.013 13.2 8.9 1.0 1 0 0 1 1 1 0 Ycf1 PIH1 PF08190.7 CDI82163.1 - 0.023 14.1 17.6 0.024 14.0 12.2 1.2 1 0 0 1 1 1 0 pre-RNA processing PIH1/Nop17 Pox_Ag35 PF03286.9 CDI82163.1 - 0.028 13.9 11.3 0.039 13.4 7.8 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein SAGA-Tad1 PF12767.2 CDI82163.1 - 0.032 13.8 18.2 0.039 13.6 12.6 1.1 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit DUF2048 PF09752.4 CDI82163.1 - 0.058 12.2 7.6 0.082 11.7 5.3 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2048) DDHD PF02862.12 CDI82163.1 - 0.065 13.0 13.9 0.076 12.8 9.7 1.2 1 0 0 1 1 1 0 DDHD domain GAGA_bind PF06217.7 CDI82163.1 - 0.089 12.7 14.9 0.1 12.5 10.3 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family MMR1 PF08505.5 CDI82163.1 - 0.098 12.6 19.2 0.11 12.4 13.3 1.2 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein Draxin PF15550.1 CDI82163.1 - 0.11 12.1 15.4 0.16 11.6 10.7 1.3 1 0 0 1 1 1 0 Draxin DUF2828 PF11443.3 CDI82163.1 - 0.12 10.5 9.5 0.13 10.4 6.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Raftlin PF15250.1 CDI82163.1 - 0.13 10.7 17.1 0.16 10.4 11.9 1.0 1 0 0 1 1 1 0 Raftlin AUX_IAA PF02309.11 CDI82163.1 - 0.14 11.9 12.7 0.16 11.6 8.8 1.2 1 0 0 1 1 1 0 AUX/IAA family eIF-3_zeta PF05091.7 CDI82163.1 - 0.15 10.6 21.1 0.17 10.4 14.6 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) FAM60A PF15396.1 CDI82163.1 - 0.16 11.7 14.1 0.19 11.4 9.8 1.2 1 0 0 1 1 1 0 Protein Family FAM60A FLO_LFY PF01698.11 CDI82163.1 - 0.26 10.0 16.9 0.31 9.8 11.7 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein Parvo_coat PF00740.13 CDI82163.1 - 0.27 10.1 21.0 0.3 9.9 14.5 1.0 1 0 0 1 1 1 0 Parvovirus coat protein VP2 Spore_coat_CotO PF14153.1 CDI82163.1 - 0.38 10.1 26.3 0.51 9.7 18.2 1.2 1 0 0 1 1 1 0 Spore coat protein CotO Neur_chan_memb PF02932.11 CDI82163.1 - 0.47 10.3 15.5 0.58 9.9 10.8 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DHHW PF14286.1 CDI82163.1 - 0.48 9.6 12.9 0.51 9.5 8.9 1.2 1 0 0 1 1 1 0 DHHW protein CDC45 PF02724.9 CDI82163.1 - 0.56 8.1 15.9 0.68 7.8 11.0 1.1 1 0 0 1 1 1 0 CDC45-like protein Spore_YhcN_YlaJ PF09580.5 CDI82163.1 - 0.62 10.1 15.8 0.79 9.8 10.9 1.3 1 0 0 1 1 1 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) DUF1510 PF07423.6 CDI82163.1 - 0.62 9.3 21.1 0.82 8.9 14.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Chorismate_synt PF01264.16 CDI82163.1 - 0.64 8.4 8.7 0.9 7.9 6.0 1.4 1 0 0 1 1 1 0 Chorismate synthase EIF4E-T PF10477.4 CDI82163.1 - 0.77 8.4 18.5 0.89 8.2 12.8 1.1 1 0 0 1 1 1 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E Asp-B-Hydro_N PF05279.6 CDI82163.1 - 0.98 9.2 13.4 1.2 8.9 9.3 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region NARP1 PF12569.3 CDI82163.1 - 1.2 7.8 21.6 1.5 7.4 15.0 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 BORG_CEP PF14957.1 CDI82163.1 - 1.2 10.0 13.3 2 9.3 9.2 1.4 1 0 0 1 1 1 0 Cdc42 effector PAT1 PF09770.4 CDI82163.1 - 1.3 7.2 54.5 1.4 7.0 37.8 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 IncA PF04156.9 CDI82163.1 - 1.3 8.5 35.1 0.024 14.2 18.9 2.0 1 1 1 2 2 2 0 IncA protein Cellulose_synt PF03552.9 CDI82163.1 - 1.4 7.1 5.9 1.6 6.9 4.1 1.0 1 0 0 1 1 1 0 Cellulose synthase DUF4220 PF13968.1 CDI82163.1 - 1.4 7.9 8.8 1.7 7.6 6.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4220) Peptidase_S49_N PF08496.5 CDI82163.1 - 1.6 8.4 17.7 2.9 7.6 12.2 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal PPP4R2 PF09184.6 CDI82163.1 - 1.7 8.1 14.4 2.1 7.8 10.0 1.1 1 0 0 1 1 1 0 PPP4R2 Paramyxo_ncap PF00973.14 CDI82163.1 - 1.8 7.1 15.9 2 7.0 11.0 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein SAPS PF04499.10 CDI82163.1 - 2.1 6.9 17.2 2.5 6.6 11.9 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein AvrE PF11725.3 CDI82163.1 - 2.4 5.0 30.8 2.8 4.8 21.3 1.0 1 0 0 1 1 1 0 Pathogenicity factor Presenilin PF01080.12 CDI82163.1 - 2.4 6.8 13.6 2.9 6.6 9.4 1.1 1 0 0 1 1 1 0 Presenilin DUF3523 PF12037.3 CDI82163.1 - 2.9 6.7 32.4 3.6 6.4 22.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3523) Hid1 PF12722.2 CDI82163.1 - 3.4 5.2 20.5 4 4.9 14.2 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF4638 PF15472.1 CDI82163.1 - 3.9 6.9 16.7 5.1 6.6 11.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) DUF2347 PF09804.4 CDI82163.1 - 3.9 6.6 12.7 4.8 6.3 8.8 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2347) Exonuc_VII_L PF02601.10 CDI82163.1 - 4 6.5 21.3 4.6 6.3 14.8 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Peptidase_S64 PF08192.6 CDI82163.1 - 4.1 5.6 18.5 4.8 5.3 12.8 1.0 1 0 0 1 1 1 0 Peptidase family S64 Baculo_PP31 PF05311.6 CDI82163.1 - 4.6 6.4 17.8 7.7 5.7 12.3 1.4 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) Peptidase_U57 PF05582.7 CDI82163.1 - 4.6 6.1 13.9 6 5.7 9.7 1.2 1 0 0 1 1 1 0 YabG peptidase U57 Med5 PF08689.5 CDI82163.1 - 5.4 4.5 16.7 5.7 4.4 11.6 1.0 1 0 0 1 1 1 0 Mediator complex subunit Med5 YjgP_YjgQ PF03739.9 CDI82163.1 - 5.4 5.6 8.8 6.7 5.3 6.1 1.2 1 0 0 1 1 1 0 Predicted permease YjgP/YjgQ family VID27 PF08553.5 CDI82163.1 - 7.1 4.7 14.5 8.4 4.4 10.0 1.1 1 0 0 1 1 1 0 VID27 cytoplasmic protein TFIIA PF03153.8 CDI82163.1 - 7.3 6.3 49.7 9.2 6.0 34.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit APG6 PF04111.7 CDI82163.1 - 7.5 5.4 24.7 9.3 5.1 17.1 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF2215 PF10225.4 CDI82163.1 - 7.8 5.8 9.4 10 5.4 6.5 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) Med19 PF10278.4 CDI82163.1 - 8.8 5.9 18.9 13 5.4 13.1 1.3 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 BTV_NS2 PF04514.7 CDI82163.1 - 9 5.0 15.6 11 4.7 10.8 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 LMBR1 PF04791.11 CDI82163.1 - 9.5 4.6 9.8 11 4.4 6.8 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein FYDLN_acid PF09538.5 CDI82163.1 - 10 6.7 14.6 1.6 9.3 6.8 1.9 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) Ribosomal_60s PF00428.14 CDI82165.1 - 0.0008 19.7 10.3 0.0008 19.7 7.1 5.4 4 1 1 5 5 5 3 60s Acidic ribosomal protein HlyD_2 PF12700.2 CDI82170.1 - 0.0041 16.3 18.4 0.0043 16.2 12.8 1.1 1 0 0 1 1 1 1 HlyD family secretion protein SAPS PF04499.10 CDI82170.1 - 0.0052 15.4 19.4 0.0047 15.6 13.5 1.0 1 0 0 1 1 1 1 SIT4 phosphatase-associated protein Utp14 PF04615.8 CDI82170.1 - 0.04 12.1 32.7 0.042 12.0 22.7 1.0 1 0 0 1 1 1 0 Utp14 protein LMBR1 PF04791.11 CDI82170.1 - 0.06 11.9 10.9 0.061 11.8 7.6 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF4045 PF13254.1 CDI82170.1 - 0.6 9.3 31.6 0.71 9.0 21.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) PLRV_ORF5 PF01690.12 CDI82170.1 - 0.89 8.6 28.6 0.98 8.4 19.8 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Pox_Ag35 PF03286.9 CDI82170.1 - 1.4 8.3 18.8 2.4 7.6 13.1 1.5 1 0 0 1 1 1 0 Pox virus Ag35 surface protein SAGA-Tad1 PF12767.2 CDI82170.1 - 2.6 7.6 36.2 3.6 7.1 25.1 1.3 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit Raftlin PF15250.1 CDI82170.1 - 2.7 6.4 30.0 3.2 6.1 20.8 1.2 1 0 0 1 1 1 0 Raftlin Neur_chan_memb PF02932.11 CDI82170.1 - 2.9 7.7 26.2 3.6 7.3 18.1 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Sporozoite_P67 PF05642.6 CDI82170.1 - 3.3 5.4 22.5 4.3 5.0 15.6 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen RNA_pol_Rpb1_5 PF04998.12 CDI82170.1 - 3.4 6.8 16.0 5.5 6.1 11.1 1.4 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 Herpes_UL87 PF03043.9 CDI82170.1 - 4.3 5.6 18.6 4.3 5.6 12.9 1.1 1 0 0 1 1 1 0 Herpesvirus UL87 family DUF4131 PF13567.1 CDI82171.1 - 0.00012 21.5 5.4 0.00016 21.1 3.7 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4131) DUF1510 PF07423.6 CDI82171.1 - 0.00021 20.7 5.9 0.00024 20.5 4.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) Peptidase_S49_N PF08496.5 CDI82171.1 - 0.00023 21.0 16.2 0.00026 20.8 11.3 1.0 1 0 0 1 1 1 1 Peptidase family S49 N-terminal Pex24p PF06398.6 CDI82171.1 - 0.00038 19.3 1.2 0.00047 19.0 0.8 1.2 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin Ion_trans PF00520.26 CDI82171.1 - 0.0016 17.7 2.8 0.0018 17.6 1.9 1.1 1 0 0 1 1 1 1 Ion transport protein DUF3487 PF11990.3 CDI82171.1 - 0.0045 16.3 7.4 0.0058 16.0 5.1 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF3487) Shisa PF13908.1 CDI82171.1 - 0.013 15.7 14.5 0.015 15.4 10.0 1.1 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator SID-1_RNA_chan PF13965.1 CDI82171.1 - 0.018 13.2 12.9 0.023 12.9 9.0 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DUF3260 PF11658.3 CDI82171.1 - 0.036 12.2 20.5 0.038 12.1 14.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3260) HemY_N PF07219.8 CDI82171.1 - 0.057 12.9 6.6 0.08 12.5 4.6 1.3 1 0 0 1 1 1 0 HemY protein N-terminus Ycf1 PF05758.7 CDI82171.1 - 0.059 11.0 15.6 0.065 10.9 10.8 1.0 1 0 0 1 1 1 0 Ycf1 IgaA PF07095.6 CDI82171.1 - 0.1 10.3 11.7 0.12 10.1 8.1 1.0 1 0 0 1 1 1 0 Intracellular growth attenuator protein IgaA DUF3646 PF12362.3 CDI82171.1 - 0.11 12.4 14.6 0.16 11.9 10.1 1.2 1 0 0 1 1 1 0 DNA polymerase III gamma and tau subunits C terminal DUF3810 PF12725.2 CDI82171.1 - 0.13 11.0 13.6 0.16 10.8 9.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) DUF4446 PF14584.1 CDI82171.1 - 0.2 11.4 23.4 0.33 10.7 16.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF4446) P5-ATPase PF12409.3 CDI82171.1 - 0.2 11.4 3.9 0.27 11.0 2.7 1.3 1 0 0 1 1 1 0 P5-type ATPase cation transporter Nucleoside_tran PF01733.13 CDI82171.1 - 0.33 10.0 6.3 0.44 9.6 4.4 1.3 1 0 0 1 1 1 0 Nucleoside transporter DUF3365 PF11845.3 CDI82171.1 - 0.39 10.5 12.1 0.55 10.0 8.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3365) PSI_PsaF PF02507.10 CDI82171.1 - 0.44 10.0 7.0 0.64 9.5 4.9 1.3 1 1 0 1 1 1 0 Photosystem I reaction centre subunit III DUF4512 PF14975.1 CDI82171.1 - 0.48 11.2 4.5 0.66 10.8 3.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4512) Choline_transpo PF04515.7 CDI82171.1 - 0.68 8.6 4.4 0.99 8.0 3.1 1.4 1 1 0 1 1 1 0 Plasma-membrane choline transporter AAA_11 PF13086.1 CDI82171.1 - 0.84 9.1 16.3 0.89 9.0 11.3 1.0 1 0 0 1 1 1 0 AAA domain PRA1 PF03208.14 CDI82171.1 - 1 8.6 8.8 1.2 8.4 6.0 1.4 1 1 0 1 1 1 0 PRA1 family protein Neur_chan_memb PF02932.11 CDI82171.1 - 1 9.1 18.8 1.6 8.5 13.0 1.3 1 1 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region MRP-S26 PF14943.1 CDI82171.1 - 1.5 8.3 20.5 1.7 8.1 14.2 1.1 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 PAT1 PF09770.4 CDI82171.1 - 1.6 6.8 45.8 1.6 6.8 31.7 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TRAP_alpha PF03896.11 CDI82171.1 - 1.7 7.5 11.1 2.5 7.0 7.7 1.3 1 1 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Tic20 PF09685.5 CDI82171.1 - 1.7 8.6 7.8 2.2 8.2 5.4 1.2 1 0 0 1 1 1 0 Tic20-like protein Neur PF00064.13 CDI82171.1 - 1.9 6.5 9.3 2.1 6.3 6.5 1.0 1 0 0 1 1 1 0 Neuraminidase Amidase PF01425.16 CDI82171.1 - 2.2 7.0 8.0 2.6 6.8 5.6 1.0 1 0 0 1 1 1 0 Amidase DUF1512 PF07431.7 CDI82171.1 - 2.7 6.6 11.5 3.2 6.4 8.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1512) DDHD PF02862.12 CDI82171.1 - 3.1 7.5 13.3 3.8 7.2 9.2 1.1 1 0 0 1 1 1 0 DDHD domain ORC5_C PF14630.1 CDI82171.1 - 4 6.8 11.1 4.4 6.6 7.7 1.1 1 0 0 1 1 1 0 Origin recognition complex (ORC) subunit 5 C-terminus UPF0118 PF01594.11 CDI82171.1 - 4.9 6.0 11.3 7.5 5.4 7.8 1.4 1 0 0 1 1 1 0 Domain of unknown function DUF20 Peptidase_S15 PF02129.13 CDI82171.1 - 6.3 6.1 12.6 7.5 5.8 8.7 1.1 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) MacB_PCD PF12704.2 CDI82171.1 - 6.6 6.2 11.7 10 5.6 8.1 1.4 1 1 0 1 1 1 0 MacB-like periplasmic core domain Band_3_cyto PF07565.8 CDI82171.1 - 8.1 5.8 18.9 8.3 5.8 13.1 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain DUF3449 PF11931.3 CDI82171.1 - 9.2 5.7 19.5 11 5.4 13.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3449) PAT1 PF09770.4 CDI82173.1 - 0.72 8.0 116.6 0.36 9.0 55.0 2.3 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 SNF2_N PF00176.18 CDI82174.1 - 9.4e-07 27.9 14.4 8.7e-06 24.7 0.0 3.8 2 2 2 4 4 4 2 SNF2 family N-terminal domain DUF2052 PF09747.4 CDI82174.1 - 0.007 16.3 17.9 0.007 16.3 12.4 2.5 2 0 0 2 2 2 2 Coiled-coil domain containing protein (DUF2052) DUF1528 PF07515.6 CDI82174.1 - 0.051 13.6 0.8 0.051 13.6 0.5 3.1 2 1 0 2 2 2 0 Protein of unknown function (DUF1528) YjgP_YjgQ PF03739.9 CDI82174.1 - 0.73 8.5 14.0 0.15 10.7 6.2 2.0 2 0 0 2 2 2 0 Predicted permease YjgP/YjgQ family CDC45 PF02724.9 CDI82174.1 - 8.3 4.3 34.8 0.023 12.7 11.5 2.6 2 1 1 3 3 3 0 CDC45-like protein DUF607 PF04678.8 CDI82174.1 - 8.9 6.1 20.5 0.69 9.8 0.1 2.9 2 0 0 2 2 2 0 Protein of unknown function, DUF607 Vfa1 PF08432.5 CDI82174.1 - 9.4 6.2 32.1 6.1 6.8 15.5 2.6 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 Macoilin PF09726.4 CDI82180.1 - 0.012 13.9 38.3 0.032 12.5 22.4 2.1 2 0 0 2 2 2 0 Transmembrane protein DUF1180 PF06679.7 CDI82180.1 - 0.015 15.1 6.2 3.7 7.3 2.1 3.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1180) E7 PF00527.13 CDI82180.1 - 0.028 14.5 4.8 0.028 14.5 3.4 4.6 3 1 0 3 3 1 0 E7 protein, Early protein TMEM154 PF15102.1 CDI82180.1 - 0.039 13.6 0.5 0.039 13.6 0.3 4.9 2 1 3 5 5 3 0 TMEM154 protein family Med15 PF09606.5 CDI82180.1 - 0.16 10.1 105.7 0.26 9.4 14.5 2.1 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal Borrelia_P83 PF05262.6 CDI82180.1 - 0.19 9.9 39.5 0.0059 14.9 18.4 2.1 2 0 0 2 2 2 0 Borrelia P83/100 protein Cytochrom_B_N PF00033.14 CDI82180.1 - 0.48 9.7 1.5 1.3 8.3 0.1 2.2 2 0 0 2 2 2 0 Cytochrome b(N-terminal)/b6/petB Utp14 PF04615.8 CDI82180.1 - 2.1 6.3 51.8 3 5.8 31.8 2.1 2 0 0 2 2 2 0 Utp14 protein TFIIA PF03153.8 CDI82180.1 - 3.3 7.4 72.7 0.41 10.4 6.5 2.3 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit PLRV_ORF5 PF01690.12 CDI82180.1 - 6.8 5.7 39.1 19 4.2 24.1 2.1 2 0 0 2 2 2 0 Potato leaf roll virus readthrough protein SAGA-Tad1 PF12767.2 CDI82180.1 - 7.5 6.1 47.6 2 8.0 2.8 2.5 2 0 0 2 2 2 0 Transcriptional regulator of RNA polII, SAGA, subunit DUF4366 PF14283.1 CDI82182.1 - 0.022 14.1 6.6 0.025 14.0 4.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) BatD PF13584.1 CDI82182.1 - 0.038 12.5 10.4 0.041 12.4 7.2 1.0 1 0 0 1 1 1 0 Oxygen tolerance Trp_oprn_chp PF09534.5 CDI82182.1 - 0.11 12.0 7.3 0.12 11.9 5.1 1.0 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Zip PF02535.17 CDI82182.1 - 0.25 10.3 1.3 0.26 10.2 0.9 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter COX6A PF02046.10 CDI82182.1 - 0.26 11.2 6.1 0.39 10.6 4.2 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase subunit VIa Leo1 PF04004.8 CDI82182.1 - 0.29 10.8 10.2 0.33 10.6 7.1 1.1 1 0 0 1 1 1 0 Leo1-like protein RskA PF10099.4 CDI82182.1 - 0.55 9.9 18.3 1 9.0 12.7 1.4 1 1 0 1 1 1 0 Anti-sigma-K factor rskA DUF2681 PF10883.3 CDI82182.1 - 0.68 10.1 28.6 0.54 10.4 2.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) DUF853 PF05872.7 CDI82182.1 - 0.79 8.0 12.0 0.91 7.7 8.3 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) DUF3357 PF11837.3 CDI82182.1 - 1 9.2 4.0 2.6 7.9 2.8 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF3357) Cas_Cas1 PF01867.11 CDI82182.1 - 1.3 8.0 11.8 2.1 7.3 8.2 1.4 1 1 0 1 1 1 0 CRISPR associated protein Cas1 FAM222A PF15258.1 CDI82182.1 - 1.5 7.9 24.4 1.9 7.6 16.9 1.2 1 0 0 1 1 1 0 Protein family of FAM222A DDHD PF02862.12 CDI82182.1 - 1.8 8.2 14.3 2.3 7.9 9.9 1.2 1 0 0 1 1 1 0 DDHD domain SPX PF03105.14 CDI82182.1 - 2.6 7.7 15.1 2.8 7.6 10.5 1.1 1 0 0 1 1 1 0 SPX domain DUF1395 PF07160.7 CDI82182.1 - 2.7 7.4 17.5 3.2 7.1 12.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1395) GAGA_bind PF06217.7 CDI82182.1 - 3.6 7.4 16.4 4.2 7.2 11.4 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family GPCR_chapero_1 PF11904.3 CDI82182.1 - 5.3 6.0 14.3 5.9 5.9 9.9 1.0 1 0 0 1 1 1 0 GPCR-chaperone SAPS PF04499.10 CDI82182.1 - 5.4 5.5 14.9 6.1 5.3 10.3 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Presenilin PF01080.12 CDI82182.1 - 7.6 5.2 9.8 8.7 5.0 6.8 1.1 1 0 0 1 1 1 0 Presenilin FLO_LFY PF01698.11 CDI82182.1 - 9.6 4.9 18.8 11 4.6 13.1 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein Trp_oprn_chp PF09534.5 CDI82183.1 - 0.0029 17.2 7.4 0.0029 17.2 5.1 8.5 6 3 2 8 8 8 1 Tryptophan-associated transmembrane protein (Trp_oprn_chp) 7TM_GPCR_Sru PF10322.4 CDI82183.1 - 1.3 8.0 1.9 2.9 6.9 0.1 2.7 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Sru Macoilin PF09726.4 CDI82184.1 - 0.018 13.3 48.9 0.022 13.0 33.9 1.1 1 0 0 1 1 1 0 Transmembrane protein DUF912 PF06024.7 CDI82185.1 - 0.003 17.5 4.0 0.003 17.5 2.8 8.5 7 2 1 8 8 8 1 Nucleopolyhedrovirus protein of unknown function (DUF912) AAA_23 PF13476.1 CDI82185.1 - 0.011 16.0 8.9 0.011 16.0 6.2 6.1 6 0 0 6 6 6 0 AAA domain TAS2R PF05296.8 CDI82185.1 - 0.07 12.0 0.5 0.15 10.9 0.3 1.5 1 0 0 1 1 1 0 Mammalian taste receptor protein (TAS2R) DUF747 PF05346.6 CDI82185.1 - 1.1 8.2 5.5 0.63 9.0 0.1 2.6 2 0 0 2 2 2 0 Eukaryotic membrane protein family Pkinase PF00069.20 CDI82186.1 - 5.3e-19 68.3 0.0 7.2e-10 38.4 0.0 6.6 7 0 0 7 7 7 2 Protein kinase domain SR-25 PF10500.4 CDI82188.1 - 1.7 8.0 18.4 1.8 7.9 12.8 1.0 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein 2OG-FeII_Oxy_5 PF13759.1 CDI82188.1 - 4.8 7.5 10.1 5.1 7.4 7.0 1.1 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase RNA_pol_Rpc4 PF05132.9 CDI82188.1 - 5.5 6.9 16.1 6.5 6.7 11.2 1.2 1 0 0 1 1 1 0 RNA polymerase III RPC4 zf-DHHC PF01529.15 CDI82191.1 - 0.044 13.1 0.2 0.075 12.4 0.1 1.6 1 0 0 1 1 1 0 DHHC palmitoyltransferase Ycf1 PF05758.7 CDI82191.1 - 1.1 6.9 13.5 1.4 6.4 9.4 1.1 1 0 0 1 1 1 0 Ycf1 DUF2232 PF09991.4 CDI82191.1 - 2.3 7.1 5.3 5.3 5.9 3.7 1.6 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) Cellulose_synt PF03552.9 CDI82191.1 - 8.4 4.5 6.4 12 4.0 4.4 1.2 1 0 0 1 1 1 0 Cellulose synthase DUF1510 PF07423.6 CDI82201.1 - 0.25 10.6 17.2 0.24 10.7 11.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Tfb4 PF03850.9 CDI82201.1 - 0.91 8.7 14.0 0.92 8.7 9.7 1.0 1 0 0 1 1 1 0 Transcription factor Tfb4 Serinc PF03348.10 CDI82201.1 - 1.1 7.9 15.4 1 7.9 10.7 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) AIF_C PF14721.1 CDI82201.1 - 1.7 8.8 15.9 1.8 8.7 11.0 1.1 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Neur_chan_memb PF02932.11 CDI82201.1 - 3.6 7.3 12.2 3.5 7.4 8.5 1.0 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Herpes_UL4 PF03277.8 CDI82201.1 - 4.3 6.5 11.9 4.6 6.4 8.3 1.2 1 0 0 1 1 1 0 Herpesvirus UL4 family DUF2072 PF09845.4 CDI82201.1 - 4.4 7.2 14.5 4.8 7.1 10.0 1.0 1 0 0 1 1 1 0 Zn-ribbon containing protein (DUF2072) Di19_C PF14571.1 CDI82201.1 - 4.6 7.6 16.6 5.3 7.3 11.5 1.1 1 0 0 1 1 1 0 Stress-induced protein Di19, C-terminal Peroxin-13_N PF04088.8 CDI82201.1 - 6.9 6.6 10.8 8.8 6.2 7.5 1.3 1 0 0 1 1 1 0 Peroxin 13, N-terminal region Zip PF02535.17 CDI82201.1 - 8 5.3 16.8 8.2 5.3 11.7 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter AraC_binding_2 PF14525.1 CDI82202.1 - 0.78 9.2 9.0 1 8.8 6.2 1.2 1 0 0 1 1 1 0 AraC-binding-like domain DUF3597 PF12200.3 CDI82202.1 - 1 9.7 7.1 1.3 9.3 4.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3597) DUF3157 PF11355.3 CDI82202.1 - 1.2 8.3 6.1 1.6 8.0 4.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3157) Calici_coat PF00915.15 CDI82202.1 - 2.8 6.7 5.1 3 6.6 3.5 1.0 1 0 0 1 1 1 0 Calicivirus coat protein DUF2057 PF09829.4 CDI82202.1 - 4.8 6.7 9.2 6.2 6.4 6.4 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2057) Med15 PF09606.5 CDI82209.1 - 0.00088 17.6 9.3 0.00088 17.6 6.5 4.9 3 1 0 4 4 4 1 ARC105 or Med15 subunit of Mediator complex non-fungal MAPEG PF01124.13 CDI82209.1 - 0.001 18.6 0.8 0.0053 16.3 0.0 2.6 2 0 0 2 2 2 1 MAPEG family Rifin_STEVOR PF02009.11 CDI82209.1 - 0.0067 16.1 0.1 0.0067 16.1 0.1 4.0 5 0 0 5 5 5 1 Rifin/stevor family Dehydrin PF00257.14 CDI82209.1 - 0.02 15.2 0.2 0.02 15.2 0.1 7.5 5 3 1 6 6 6 0 Dehydrin DUF912 PF06024.7 CDI82209.1 - 0.098 12.7 0.1 0.098 12.7 0.1 7.0 6 2 0 6 6 6 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Nucleoplasmin PF03066.10 CDI82215.1 - 0.0019 17.7 4.7 0.0053 16.2 3.3 1.8 1 0 0 1 1 1 1 Nucleoplasmin DUF775 PF05603.7 CDI82215.1 - 0.0066 16.0 0.8 0.0066 16.0 0.6 3.7 4 0 0 4 4 4 1 Protein of unknown function (DUF775) Phostensin_N PF13916.1 CDI82215.1 - 3.7 7.6 13.6 2.7 8.0 2.0 2.4 2 0 0 2 2 2 0 PP1-regulatory protein, Phostensin N-terminal PBP1_TM PF14812.1 CDI82215.1 - 6.2 7.1 22.1 0.074 13.3 8.7 2.6 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Peptidase_A22B PF04258.8 CDI82216.1 - 1.5e-47 162.5 11.0 3.9e-44 151.3 4.8 2.3 1 1 1 2 2 2 2 Signal peptide peptidase Chromo PF00385.19 CDI82217.1 - 5.7e-09 35.5 0.9 9e-09 34.8 0.0 1.9 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain zf-CCHC PF00098.18 CDI82217.1 - 0.0012 18.6 2.0 0.003 17.4 1.4 1.7 1 0 0 1 1 1 1 Zinc knuckle Kelch_5 PF13854.1 CDI82218.1 - 4.1e-10 39.3 0.0 3.7e-06 26.7 0.0 3.5 3 0 0 3 3 3 2 Kelch motif Kelch_4 PF13418.1 CDI82218.1 - 4.6e-07 29.5 0.0 0.001 18.7 0.0 3.4 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_3 PF13415.1 CDI82218.1 - 5.6e-07 29.5 9.4 0.28 11.4 0.7 5.8 4 1 0 4 4 4 3 Galactose oxidase, central domain Kelch_6 PF13964.1 CDI82218.1 - 0.0034 17.4 0.0 0.097 12.8 0.0 3.3 3 0 0 3 3 3 1 Kelch motif UPF0203 PF05254.7 CDI82219.1 - 1.3e-07 31.3 1.0 0.014 15.1 0.0 2.4 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0203) Tmemb_cc2 PF10267.4 CDI82219.1 - 0.68 8.4 4.3 0.9 8.0 3.0 1.1 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein Thioredoxin_8 PF13905.1 CDI82220.1 - 2e-20 72.6 0.0 3.2e-20 72.0 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.1 CDI82220.1 - 4.8e-07 29.9 0.0 1.3e-06 28.6 0.0 1.7 1 1 0 1 1 1 1 Thioredoxin-like domain AhpC-TSA PF00578.16 CDI82220.1 - 7.7e-06 25.6 0.0 4.9e-05 23.0 0.0 2.1 1 1 0 1 1 1 1 AhpC/TSA family Thioredoxin PF00085.15 CDI82220.1 - 0.0011 18.5 0.0 0.025 14.2 0.0 2.3 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_7 PF13899.1 CDI82220.1 - 0.0025 17.8 0.0 0.0059 16.6 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin-like Med15 PF09606.5 CDI82225.1 - 0.0023 16.2 35.0 0.0029 15.9 24.3 1.1 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal SAGA-Tad1 PF12767.2 CDI82225.1 - 0.54 9.8 13.6 0.96 9.0 9.4 1.4 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit PAT1 PF09770.4 CDI82225.1 - 0.69 8.0 28.9 0.86 7.7 20.0 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 RED_N PF07808.8 CDI82225.1 - 1.5 7.9 13.5 3.2 6.9 9.4 1.5 1 0 0 1 1 1 0 RED-like protein N-terminal region Activator_LAG-3 PF11498.3 CDI82225.1 - 9.4 4.8 41.7 14 4.2 28.9 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Nop53 PF07767.6 CDI82227.1 - 0.0018 17.3 8.6 0.0018 17.3 6.0 1.7 2 0 0 2 2 2 1 Nop53 (60S ribosomal biogenesis) Snapin_Pallidin PF14712.1 CDI82227.1 - 0.042 14.1 2.6 1.1 9.6 0.0 2.7 3 0 0 3 3 3 0 Snapin/Pallidin HSCB_C PF07743.8 CDI82227.1 - 0.71 10.3 7.5 1.9 9.0 0.5 3.1 3 0 0 3 3 3 0 HSCB C-terminal oligomerisation domain DUF1180 PF06679.7 CDI82227.1 - 10 6.0 7.3 4.3 7.2 1.0 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF1180) Met_10 PF02475.11 CDI82228.1 - 1.7e-47 161.6 0.0 2e-47 161.4 0.0 1.1 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_18 PF12847.2 CDI82228.1 - 2.1e-06 28.2 0.3 7.6e-06 26.4 0.1 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 CDI82228.1 - 3.5e-06 27.0 0.2 1.9e-05 24.6 0.2 2.0 2 0 0 2 2 2 1 Methyltransferase domain TRM PF02005.11 CDI82228.1 - 0.00025 20.1 0.1 0.00048 19.1 0.0 1.4 1 1 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase Methyltransf_15 PF09445.5 CDI82228.1 - 0.00091 18.8 0.0 0.0014 18.2 0.0 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Cons_hypoth95 PF03602.10 CDI82228.1 - 0.0014 18.0 0.1 0.0024 17.3 0.1 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 MTS PF05175.9 CDI82228.1 - 0.0033 16.8 0.0 0.0056 16.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain SAM_MT PF04445.8 CDI82228.1 - 0.034 13.3 0.2 0.078 12.1 0.1 1.5 1 1 0 1 1 1 0 Putative SAM-dependent methyltransferase Methyltransf_31 PF13847.1 CDI82228.1 - 0.099 12.2 0.0 0.51 9.9 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain Na_trans_assoc PF06512.8 CDI82229.1 - 0.05 13.5 11.5 0.062 13.2 8.0 1.2 1 0 0 1 1 1 0 Sodium ion transport-associated GAGA_bind PF06217.7 CDI82229.1 - 0.3 11.0 13.0 0.35 10.7 9.0 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family DUF853 PF05872.7 CDI82229.1 - 0.44 8.8 10.2 0.55 8.5 7.1 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) NPR3 PF03666.8 CDI82229.1 - 0.55 8.7 15.7 0.77 8.2 10.9 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 AvrE PF11725.3 CDI82229.1 - 0.56 7.1 19.2 0.62 7.0 13.3 1.0 1 0 0 1 1 1 0 Pathogenicity factor Spore_coat_CotO PF14153.1 CDI82229.1 - 0.93 8.9 24.7 1.6 8.1 17.1 1.4 1 0 0 1 1 1 0 Spore coat protein CotO Hid1 PF12722.2 CDI82229.1 - 1 6.9 17.1 1.3 6.5 11.9 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein MIP-T3 PF10243.4 CDI82229.1 - 1.2 7.5 31.2 1.7 7.0 21.6 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Apt1 PF10351.4 CDI82229.1 - 1.5 7.6 14.4 1.9 7.2 10.0 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Suf PF05843.9 CDI82229.1 - 1.6 8.3 11.2 2.1 8.0 7.8 1.4 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF2201_N PF13203.1 CDI82229.1 - 1.9 7.5 16.1 3.2 6.8 11.2 1.3 1 0 0 1 1 1 0 Putative metallopeptidase domain Parvo_coat PF00740.13 CDI82229.1 - 2 7.3 12.2 2.2 7.1 8.5 1.0 1 0 0 1 1 1 0 Parvovirus coat protein VP2 Ycf1 PF05758.7 CDI82229.1 - 2.1 5.9 14.8 2.2 5.8 10.3 1.1 1 0 0 1 1 1 0 Ycf1 Adeno_hexon PF01065.14 CDI82229.1 - 2.2 7.0 6.7 3 6.5 4.6 1.2 1 0 0 1 1 1 0 Hexon, adenovirus major coat protein, N-terminal domain FLO_LFY PF01698.11 CDI82229.1 - 2.6 6.7 17.3 3.6 6.3 12.0 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein Adeno_PIX PF03955.9 CDI82229.1 - 4.5 7.8 8.8 5.3 7.6 0.0 2.3 2 0 0 2 2 2 0 Adenovirus hexon-associated protein (IX) Paf1 PF03985.8 CDI82229.1 - 4.9 5.7 20.8 6.6 5.3 14.4 1.2 1 0 0 1 1 1 0 Paf1 Pex16 PF08610.5 CDI82229.1 - 7.7 5.4 13.8 11 4.9 9.5 1.2 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) Ribosomal_60s PF00428.14 CDI82250.1 - 0.0048 17.2 57.6 0.0061 16.9 2.5 4.3 4 0 0 4 4 4 3 60s Acidic ribosomal protein Med15 PF09606.5 CDI82250.1 - 0.042 12.0 42.1 0.0053 15.0 8.1 2.2 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal Glyco_hydro_85 PF03644.8 CDI82250.1 - 0.76 8.8 9.0 0.13 11.3 2.5 2.0 2 0 0 2 2 2 0 Glycosyl hydrolase family 85 Activator_LAG-3 PF11498.3 CDI82250.1 - 0.88 8.2 44.5 0.35 9.5 12.2 2.3 2 0 0 2 2 2 0 Transcriptional activator LAG-3 SR-25 PF10500.4 CDI82255.1 - 0.00012 21.6 37.9 0.00012 21.6 26.3 5.5 3 2 2 5 5 5 1 Nuclear RNA-splicing-associated protein HemY_N PF07219.8 CDI82255.1 - 0.0038 16.7 8.4 0.0038 16.7 5.8 6.7 3 3 6 9 9 9 1 HemY protein N-terminus STT3 PF02516.9 CDI82255.1 - 0.38 9.6 3.3 0.59 9.0 2.3 1.3 1 0 0 1 1 1 0 Oligosaccharyl transferase STT3 subunit DUF2142 PF09913.4 CDI82255.1 - 4.5 5.8 9.1 0.041 12.5 0.5 1.9 2 0 0 2 2 2 0 Predicted membrane protein (DUF2142) LMBR1 PF04791.11 CDI82259.1 - 0.023 13.2 1.2 0.023 13.2 0.8 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Mem_trans PF03547.13 CDI82259.1 - 0.037 12.3 1.7 0.037 12.3 1.2 1.2 1 0 0 1 1 1 0 Membrane transport protein SAPS PF04499.10 CDI82259.1 - 0.04 12.5 17.3 0.052 12.1 12.0 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Pox_Ag35 PF03286.9 CDI82259.1 - 0.056 12.9 16.2 0.091 12.2 11.2 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Otopetrin PF03189.8 CDI82259.1 - 0.062 12.3 0.5 0.064 12.2 0.3 1.2 1 0 0 1 1 1 0 Otopetrin HlyD_2 PF12700.2 CDI82259.1 - 4.8 6.2 22.3 6.6 5.7 15.5 1.2 1 0 0 1 1 1 0 HlyD family secretion protein Tim54 PF11711.3 CDI82259.1 - 7.3 5.0 18.0 18 3.7 12.5 1.7 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 HC2 PF07382.6 CDI82260.1 - 0.12 12.1 69.6 1.4 8.7 24.6 2.2 1 1 1 2 2 2 0 Histone H1-like nucleoprotein HC2 CAF-1_p150 PF11600.3 CDI82264.1 - 0.00063 19.1 29.0 0.00063 19.1 20.1 3.1 3 0 0 3 3 3 2 Chromatin assembly factor 1 complex p150 subunit, N-terminal RskA PF10099.4 CDI82264.1 - 0.022 14.5 1.3 0.022 14.5 0.9 2.8 2 1 0 2 2 2 0 Anti-sigma-K factor rskA DUF3025 PF11227.3 CDI82264.1 - 0.033 13.6 0.8 0.081 12.4 0.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3025) PAT1 PF09770.4 CDI82264.1 - 0.33 9.1 38.7 0.0048 15.2 21.8 1.4 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 DUF3373 PF11853.3 CDI82264.1 - 2.2 6.7 13.8 0.44 9.0 1.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3373) RAP1 PF07218.6 CDI82265.1 - 0.045 11.8 5.4 0.057 11.5 3.7 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) FimP PF09766.4 CDI82265.1 - 0.27 10.2 18.0 0.12 11.3 10.9 1.7 2 0 0 2 2 2 0 Fms-interacting protein IncA PF04156.9 CDI82265.1 - 2.1 7.8 20.3 0.021 14.4 5.7 2.7 2 1 0 2 2 2 0 IncA protein EPL1 PF10513.4 CDI82265.1 - 7 6.8 17.1 13 5.9 6.2 2.4 2 0 0 2 2 2 0 Enhancer of polycomb-like DUF788 PF05620.6 CDI82265.1 - 8.9 6.1 10.5 19 5.0 7.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF788) zf-C3HC4 PF00097.20 CDI82268.1 - 0.066 12.8 0.5 0.14 11.8 0.4 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) KIF1B PF12423.3 CDI82268.1 - 0.13 12.2 0.7 0.92 9.5 0.0 2.3 2 0 0 2 2 2 0 Kinesin protein 1B LSM PF01423.17 CDI82270.1 - 3.7e-16 58.4 0.3 4.5e-16 58.1 0.2 1.2 1 0 0 1 1 1 1 LSM domain SPC22 PF04573.7 CDI82271.1 - 4.5e-35 120.4 0.0 5.5e-35 120.1 0.0 1.1 1 0 0 1 1 1 1 Signal peptidase subunit TSA PF03249.8 CDI82271.1 - 0.0033 16.0 2.4 0.0044 15.6 1.6 1.1 1 0 0 1 1 1 1 Type specific antigen DUF976 PF06162.7 CDI82271.1 - 0.012 15.1 0.4 0.091 12.2 0.0 2.0 1 1 1 2 2 2 0 Caenorhabditis elegans protein of unknown function (DUF976) His_Phos_1 PF00300.17 CDI82272.1 - 3.6e-05 23.9 0.0 0.00038 20.5 0.1 2.0 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) CAF-1_p150 PF11600.3 CDI82280.1 - 6.1e-05 22.5 29.4 7.1e-05 22.2 20.4 1.1 1 0 0 1 1 1 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal CDC45 PF02724.9 CDI82280.1 - 0.00036 18.7 21.3 0.00039 18.6 14.8 1.1 1 0 0 1 1 1 1 CDC45-like protein Med15 PF09606.5 CDI82280.1 - 0.00086 17.6 93.3 0.0011 17.3 64.7 1.0 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal Ycf1 PF05758.7 CDI82280.1 - 0.0032 15.3 23.8 0.0034 15.2 16.5 1.0 1 0 0 1 1 1 1 Ycf1 MIP-T3 PF10243.4 CDI82280.1 - 0.0034 15.9 36.0 0.0042 15.6 25.0 1.1 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 Paramyxo_ncap PF00973.14 CDI82280.1 - 0.0056 15.4 22.9 0.0074 15.0 15.9 1.2 1 0 0 1 1 1 1 Paramyxovirus nucleocapsid protein GAGA_bind PF06217.7 CDI82280.1 - 0.0082 16.1 27.3 0.0097 15.9 18.9 1.1 1 0 0 1 1 1 1 GAGA binding protein-like family DUF1510 PF07423.6 CDI82280.1 - 0.0093 15.3 31.1 0.014 14.8 21.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) Hid1 PF12722.2 CDI82280.1 - 0.018 12.7 29.4 0.019 12.6 20.4 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein PAT1 PF09770.4 CDI82280.1 - 0.089 11.0 74.5 0.1 10.8 51.6 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Parvo_coat PF00740.13 CDI82280.1 - 0.14 11.0 32.5 0.16 10.8 22.6 1.1 1 0 0 1 1 1 0 Parvovirus coat protein VP2 DUF4045 PF13254.1 CDI82280.1 - 0.21 10.8 29.0 0.26 10.5 20.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) SAGA-Tad1 PF12767.2 CDI82280.1 - 0.34 10.5 37.0 0.45 10.1 25.6 1.1 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit Herpes_UL87 PF03043.9 CDI82280.1 - 0.36 9.1 14.4 0.45 8.8 10.0 1.2 1 0 0 1 1 1 0 Herpesvirus UL87 family GPCR_chapero_1 PF11904.3 CDI82280.1 - 1.1 8.3 26.1 1.4 7.9 18.1 1.3 1 0 0 1 1 1 0 GPCR-chaperone U79_P34 PF03064.11 CDI82280.1 - 1.1 8.7 27.7 1.6 8.2 19.2 1.2 1 0 0 1 1 1 0 HSV U79 / HCMV P34 AvrE PF11725.3 CDI82280.1 - 1.2 6.0 33.7 1.4 5.8 23.4 1.0 1 0 0 1 1 1 0 Pathogenicity factor DUF342 PF03961.8 CDI82280.1 - 1.6 7.0 17.2 1.9 6.8 11.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) K_trans PF02705.11 CDI82280.1 - 2.1 6.6 8.1 2.5 6.3 5.6 1.2 1 0 0 1 1 1 0 K+ potassium transporter FLO_LFY PF01698.11 CDI82280.1 - 2.5 6.8 33.9 3.6 6.3 23.5 1.2 1 0 0 1 1 1 0 Floricaula / Leafy protein Neur_chan_memb PF02932.11 CDI82280.1 - 3 7.6 27.9 4.5 7.0 19.3 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region TT_ORF1 PF02956.9 CDI82280.1 - 3.5 5.9 27.0 4.8 5.5 18.7 1.1 1 0 0 1 1 1 0 TT viral orf 1 LMBR1 PF04791.11 CDI82280.1 - 3.6 6.0 15.8 4.6 5.7 10.9 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein NST1 PF13945.1 CDI82280.1 - 7.6 6.5 40.9 11 6.0 28.3 1.2 1 0 0 1 1 1 0 Salt tolerance down-regulator Dapper PF15268.1 CDI82280.1 - 8.9 4.9 40.2 10 4.7 27.9 1.0 1 0 0 1 1 1 0 Dapper Pheromone PF08015.6 CDI82292.1 - 0.34 11.7 15.6 0.18 12.6 5.8 2.6 2 0 0 2 2 2 0 Fungal mating-type pheromone Pox_E2-like PF04497.7 CDI82292.1 - 1.8 6.4 3.4 1.8 6.4 2.4 1.2 1 0 0 1 1 1 0 Poxviridae protein SSP160 PF06933.6 CDI82292.1 - 2.2 6.1 12.8 2.9 5.7 8.9 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Med15 PF09606.5 CDI82293.1 - 0.024 12.8 21.3 0.03 12.5 14.8 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF687 PF05095.7 CDI82293.1 - 0.027 12.8 0.6 0.031 12.6 0.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF687) DUF912 PF06024.7 CDI82293.1 - 0.039 14.0 1.7 0.048 13.7 0.3 1.7 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Activator_LAG-3 PF11498.3 CDI82293.1 - 0.068 11.9 15.7 0.078 11.7 10.9 1.3 1 0 0 1 1 1 0 Transcriptional activator LAG-3 FimP PF09766.4 CDI82293.1 - 0.2 10.6 8.4 0.25 10.3 5.8 1.1 1 0 0 1 1 1 0 Fms-interacting protein DUF3464 PF11947.3 CDI82293.1 - 0.36 10.2 3.1 0.5 9.8 2.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3464) TMEM51 PF15345.1 CDI82293.1 - 0.67 9.5 6.0 0.94 9.1 4.2 1.2 1 0 0 1 1 1 0 Transmembrane protein 51 Herpes_gE PF02480.11 CDI82293.1 - 1.2 7.3 7.5 0.29 9.3 0.2 2.0 1 1 1 2 2 2 0 Alphaherpesvirus glycoprotein E Ilar_coat PF01787.11 CDI82293.1 - 2.9 7.4 7.0 3.7 7.0 4.8 1.1 1 0 0 1 1 1 0 Ilarvirus coat protein Trypan_glycop_C PF10659.4 CDI82293.1 - 3.3 8.0 7.5 2 8.7 1.3 2.2 2 0 0 2 2 2 0 Trypanosome variant surface glycoprotein C-terminal domain DivIC PF04977.10 CDI82293.1 - 6.7 6.2 9.9 12 5.5 6.9 1.3 1 0 0 1 1 1 0 Septum formation initiator TFIIA PF03153.8 CDI82293.1 - 7.4 6.3 21.8 8.3 6.2 15.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Peptidase_S49_N PF08496.5 CDI82302.1 - 0.0016 18.2 3.4 0.0017 18.2 2.3 1.0 1 0 0 1 1 1 1 Peptidase family S49 N-terminal DUF912 PF06024.7 CDI82302.1 - 0.0023 17.9 7.9 0.039 14.0 2.0 2.1 1 1 1 2 2 2 1 Nucleopolyhedrovirus protein of unknown function (DUF912) Serinc PF03348.10 CDI82302.1 - 0.011 14.4 2.9 0.013 14.2 2.0 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) Methyltransf_29 PF03141.11 CDI82302.1 - 0.016 13.6 0.4 0.017 13.5 0.3 1.0 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase PSK PF06404.7 CDI82302.1 - 0.019 15.7 3.3 0.019 15.7 2.3 1.8 2 0 0 2 2 1 0 Phytosulfokine precursor protein (PSK) DUF1510 PF07423.6 CDI82302.1 - 0.027 13.8 6.1 0.036 13.4 4.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Peroxin-13_N PF04088.8 CDI82302.1 - 0.039 13.8 2.1 0.048 13.6 1.2 1.3 1 1 0 1 1 1 0 Peroxin 13, N-terminal region CagX PF03524.10 CDI82302.1 - 0.06 12.6 2.6 0.073 12.3 1.8 1.2 1 0 0 1 1 1 0 Conjugal transfer protein FAM176 PF14851.1 CDI82302.1 - 0.083 12.5 0.9 0.13 11.9 0.6 1.3 1 0 0 1 1 1 0 FAM176 family Zip PF02535.17 CDI82302.1 - 0.1 11.5 1.2 0.12 11.3 0.8 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter TRAP_alpha PF03896.11 CDI82302.1 - 0.12 11.3 1.0 0.16 10.9 0.7 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DUF3260 PF11658.3 CDI82302.1 - 0.14 10.2 6.9 0.16 10.0 4.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3260) CPSF100_C PF13299.1 CDI82302.1 - 0.18 12.0 4.2 0.21 11.7 2.9 1.1 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Folate_carrier PF01770.13 CDI82302.1 - 0.21 10.0 2.6 0.23 9.9 1.8 1.1 1 0 0 1 1 1 0 Reduced folate carrier TFIIA PF03153.8 CDI82302.1 - 0.23 11.3 16.4 0.3 10.9 11.3 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Gryzun PF07919.7 CDI82302.1 - 0.55 8.4 10.5 0.62 8.3 7.3 1.0 1 0 0 1 1 1 0 Gryzun, putative trafficking through Golgi NapE PF06796.6 CDI82302.1 - 0.62 9.4 3.9 1.6 8.1 1.4 2.5 2 1 0 2 2 2 0 Periplasmic nitrate reductase protein NapE Band_3_cyto PF07565.8 CDI82302.1 - 0.64 9.4 11.5 0.77 9.2 8.0 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain DUF3959 PF13105.1 CDI82302.1 - 0.69 9.1 5.3 0.79 8.9 3.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3959) DUF605 PF04652.11 CDI82302.1 - 0.7 9.2 12.4 0.82 9.0 8.6 1.2 1 0 0 1 1 1 0 Vta1 like ORC5_C PF14630.1 CDI82302.1 - 0.89 8.9 5.7 1.1 8.6 3.9 1.2 1 0 0 1 1 1 0 Origin recognition complex (ORC) subunit 5 C-terminus RBM39linker PF15519.1 CDI82302.1 - 0.93 9.8 4.1 1.4 9.2 2.1 1.8 2 0 0 2 2 2 0 linker between RRM2 and RRM3 domains in RBM39 protein YfhO PF09586.5 CDI82302.1 - 0.95 7.4 6.0 1.2 7.1 4.1 1.1 1 0 0 1 1 1 0 Bacterial membrane protein YfhO DUF3984 PF13136.1 CDI82302.1 - 0.97 8.5 7.3 1.1 8.3 5.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3984) DUF3357 PF11837.3 CDI82302.1 - 1.2 9.0 4.6 2.8 7.8 3.2 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF3357) Kei1 PF08552.6 CDI82302.1 - 1.2 8.7 5.5 1.7 8.2 3.8 1.4 1 1 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 Baculo_PP31 PF05311.6 CDI82302.1 - 1.5 7.9 6.2 1.9 7.6 4.3 1.2 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) Cas1_AcylT PF07779.7 CDI82302.1 - 1.6 7.1 3.9 1.9 6.8 2.7 1.1 1 0 0 1 1 1 0 10 TM Acyl Transferase domain found in Cas1p Spore_YhcN_YlaJ PF09580.5 CDI82302.1 - 2.3 8.2 7.2 3.1 7.8 5.0 1.1 1 0 0 1 1 1 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) ALG3 PF05208.8 CDI82302.1 - 3.7 6.6 7.1 4.3 6.4 4.9 1.1 1 0 0 1 1 1 0 ALG3 protein PAT1 PF09770.4 CDI82302.1 - 4 5.5 30.4 5.3 5.1 21.1 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Pex14_N PF04695.8 CDI82302.1 - 4.1 7.4 17.0 2.7 8.0 9.8 1.8 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region G-alpha PF00503.15 CDI82302.1 - 4.9 5.7 9.2 6.1 5.4 6.4 1.1 1 0 0 1 1 1 0 G-protein alpha subunit OATP PF03137.15 CDI82302.1 - 5.3 4.9 8.8 6.1 4.7 6.1 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Conotoxin PF02950.12 CDI82302.1 - 9.5 7.1 15.0 1.2 9.9 5.5 2.2 1 1 1 2 2 2 0 Conotoxin Ank_2 PF12796.2 CDI82306.1 - 0.025 14.9 0.0 0.054 13.8 0.0 1.6 1 1 0 1 1 1 0 Ankyrin repeats (3 copies) Surfac_D-trimer PF09006.6 CDI82307.1 - 0.18 11.5 8.0 0.015 15.0 1.3 2.4 2 0 0 2 2 2 0 Lung surfactant protein D coiled-coil trimerisation Prefoldin PF02996.12 CDI82307.1 - 0.22 11.1 11.1 0.073 12.7 1.1 2.8 2 0 0 2 2 2 0 Prefoldin subunit Phage_GP20 PF06810.6 CDI82307.1 - 1.6 8.1 12.9 0.26 10.7 3.2 2.4 2 0 0 2 2 2 0 Phage minor structural protein GP20 Ribosomal_L37e PF01907.14 CDI82309.1 - 0.0011 18.6 0.9 0.0028 17.4 0.6 1.7 1 0 0 1 1 1 1 Ribosomal protein L37e Med15 PF09606.5 CDI82309.1 - 0.0085 14.3 11.1 0.0091 14.2 7.7 1.1 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal Lactamase_B_2 PF12706.2 CDI82309.1 - 0.013 15.0 0.0 0.021 14.3 0.0 1.3 1 0 0 1 1 1 0 Beta-lactamase superfamily domain Ctr PF04145.10 CDI82314.1 - 0.00011 22.3 1.2 0.00011 22.2 0.6 1.2 1 1 0 1 1 1 1 Ctr copper transporter family IncA PF04156.9 CDI82314.1 - 0.00011 21.8 9.4 0.00012 21.7 6.5 1.1 1 0 0 1 1 1 1 IncA protein BatD PF13584.1 CDI82314.1 - 0.00012 20.8 0.4 0.00013 20.7 0.3 1.0 1 0 0 1 1 1 1 Oxygen tolerance DUF1510 PF07423.6 CDI82314.1 - 0.00014 21.3 1.8 0.00016 21.0 1.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) SpoIIIAH PF12685.2 CDI82314.1 - 0.00017 21.1 0.5 0.00021 20.8 0.3 1.1 1 0 0 1 1 1 1 SpoIIIAH-like protein EphA2_TM PF14575.1 CDI82314.1 - 0.00027 21.2 3.3 0.00027 21.2 2.3 1.9 1 1 1 2 2 1 1 Ephrin type-A receptor 2 transmembrane domain FHIPEP PF00771.15 CDI82314.1 - 0.00054 18.4 0.6 0.00054 18.4 0.4 1.0 1 0 0 1 1 1 1 FHIPEP family OAD_gamma PF04277.8 CDI82314.1 - 0.00064 20.0 0.1 0.00064 20.0 0.1 1.4 2 0 0 2 2 1 1 Oxaloacetate decarboxylase, gamma chain DUF3357 PF11837.3 CDI82314.1 - 0.00069 19.4 0.4 0.00086 19.1 0.3 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF3357) GRP PF07172.6 CDI82314.1 - 0.00077 19.8 2.8 0.00077 19.8 1.9 1.5 1 1 1 2 2 1 1 Glycine rich protein family YfhO PF09586.5 CDI82314.1 - 0.00083 17.5 2.8 0.00087 17.4 1.9 1.0 1 0 0 1 1 1 1 Bacterial membrane protein YfhO Tetraspannin PF00335.15 CDI82314.1 - 0.00086 18.6 0.4 0.00086 18.6 0.2 1.5 2 0 0 2 2 1 1 Tetraspanin family DUF843 PF05814.6 CDI82314.1 - 0.001 18.8 1.4 0.0013 18.4 1.0 1.2 1 0 0 1 1 1 1 Baculovirus protein of unknown function (DUF843) Pex24p PF06398.6 CDI82314.1 - 0.0013 17.5 0.0 0.0014 17.4 0.0 1.0 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin DUF2615 PF11027.3 CDI82314.1 - 0.0018 18.1 0.9 0.0026 17.6 0.7 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF2615) TMEM154 PF15102.1 CDI82314.1 - 0.0022 17.7 7.7 0.0022 17.7 5.4 1.6 1 1 0 1 1 1 1 TMEM154 protein family DUF3278 PF11683.3 CDI82314.1 - 0.0022 17.9 0.6 0.0025 17.8 0.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3278) DUF4010 PF13194.1 CDI82314.1 - 0.0022 17.3 0.1 0.0024 17.1 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4010) Tmemb_9 PF05434.6 CDI82314.1 - 0.0023 17.7 1.5 0.0027 17.4 1.0 1.3 1 0 0 1 1 1 1 TMEM9 MAPEG PF01124.13 CDI82314.1 - 0.0027 17.2 0.0 0.0027 17.2 0.0 1.3 2 0 0 2 2 1 1 MAPEG family DUF4131 PF13567.1 CDI82314.1 - 0.0031 16.9 0.2 0.0035 16.7 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4131) DUF4381 PF14316.1 CDI82314.1 - 0.0033 17.5 3.5 0.005 16.9 2.4 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4381) FAM176 PF14851.1 CDI82314.1 - 0.0036 16.9 2.0 0.0038 16.9 1.4 1.2 1 0 0 1 1 1 1 FAM176 family 7tm_1 PF00001.16 CDI82314.1 - 0.0041 16.2 0.5 0.0047 16.1 0.4 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) SID-1_RNA_chan PF13965.1 CDI82314.1 - 0.0044 15.2 0.7 0.0047 15.1 0.5 1.0 1 0 0 1 1 1 1 dsRNA-gated channel SID-1 OSTbeta PF15048.1 CDI82314.1 - 0.005 16.9 3.9 0.0061 16.6 2.7 1.2 1 0 0 1 1 1 1 Organic solute transporter subunit beta protein CcmH PF03918.9 CDI82314.1 - 0.0051 15.8 3.9 0.0072 15.3 2.7 1.5 1 1 0 1 1 1 1 Cytochrome C biogenesis protein COPI_assoc PF08507.5 CDI82314.1 - 0.0055 16.3 0.1 0.0057 16.3 0.1 1.0 1 0 0 1 1 1 1 COPI associated protein Cytochrom_B_N PF00033.14 CDI82314.1 - 0.007 15.7 0.5 0.01 15.1 0.0 1.5 1 1 1 2 2 2 1 Cytochrome b(N-terminal)/b6/petB SHR3_chaperone PF08229.6 CDI82314.1 - 0.0075 15.2 5.7 0.008 15.1 4.0 1.2 1 0 0 1 1 1 1 ER membrane protein SH3 DUF3397 PF11877.3 CDI82314.1 - 0.008 16.1 1.0 0.0098 15.8 0.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3397) DUF3366 PF11846.3 CDI82314.1 - 0.0083 16.0 0.3 0.0096 15.8 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3366) DUF2140 PF09911.4 CDI82314.1 - 0.0087 15.2 0.9 0.012 14.8 0.6 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2140) DUF3530 PF12048.3 CDI82314.1 - 0.0088 15.0 5.6 0.011 14.7 3.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3530) DUF2393 PF09624.5 CDI82314.1 - 0.0093 15.5 1.5 0.01 15.3 0.8 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF2393) Syndecan PF01034.15 CDI82314.1 - 0.012 15.2 0.0 0.02 14.5 0.0 1.4 1 0 0 1 1 1 0 Syndecan domain Scs3p PF10261.4 CDI82314.1 - 0.013 14.6 1.4 0.018 14.1 1.0 1.3 1 0 0 1 1 1 0 Inositol phospholipid synthesis and fat-storage-inducing TM TRAP_alpha PF03896.11 CDI82314.1 - 0.013 14.5 1.7 0.013 14.5 1.2 1.4 1 1 1 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit V_ATPase_I PF01496.14 CDI82314.1 - 0.013 13.3 3.6 0.014 13.3 2.5 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TauE PF01925.14 CDI82314.1 - 0.022 14.2 0.0 0.022 14.2 0.0 1.1 1 0 0 1 1 1 0 Sulfite exporter TauE/SafE DUF2933 PF11666.3 CDI82314.1 - 0.022 14.2 8.5 0.068 12.7 5.9 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2933) 7TM_GPCR_Srv PF10323.4 CDI82314.1 - 0.023 13.8 0.4 0.026 13.6 0.3 1.3 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srv DUF2149 PF09919.4 CDI82314.1 - 0.024 14.6 3.2 0.031 14.3 2.2 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2149) Protocadherin PF08374.6 CDI82314.1 - 0.025 14.2 0.5 0.026 14.1 0.4 1.1 1 0 0 1 1 1 0 Protocadherin PRA1 PF03208.14 CDI82314.1 - 0.026 13.8 0.0 0.031 13.6 0.0 1.1 1 0 0 1 1 1 0 PRA1 family protein RskA PF10099.4 CDI82314.1 - 0.027 14.2 0.1 0.03 14.0 0.0 1.1 1 0 0 1 1 1 0 Anti-sigma-K factor rskA TRP PF06011.7 CDI82314.1 - 0.027 13.0 0.2 0.038 12.5 0.1 1.1 1 0 0 1 1 1 0 Transient receptor potential (TRP) ion channel Zn_peptidase PF04228.8 CDI82314.1 - 0.028 13.6 2.6 0.03 13.5 1.8 1.0 1 0 0 1 1 1 0 Putative neutral zinc metallopeptidase HN PF00423.14 CDI82314.1 - 0.028 12.7 1.5 0.031 12.5 1.1 1.0 1 0 0 1 1 1 0 Haemagglutinin-neuraminidase Herpes_LMP1 PF05297.6 CDI82314.1 - 0.028 13.3 1.1 0.031 13.2 0.7 1.0 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) DUF2681 PF10883.3 CDI82314.1 - 0.029 14.5 13.2 0.046 13.9 9.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) PSK PF06404.7 CDI82314.1 - 0.031 15.0 2.6 0.031 15.0 1.8 1.5 2 0 0 2 2 1 0 Phytosulfokine precursor protein (PSK) Herpes_glycop PF01528.11 CDI82314.1 - 0.038 12.6 0.2 0.04 12.6 0.2 1.1 1 0 0 1 1 1 0 Herpesvirus glycoprotein M Mem_trans PF03547.13 CDI82314.1 - 0.038 12.2 2.4 0.038 12.2 1.6 1.0 1 0 0 1 1 1 0 Membrane transport protein DUF3260 PF11658.3 CDI82314.1 - 0.039 12.1 2.6 0.039 12.1 1.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3260) DUF2269 PF10027.4 CDI82314.1 - 0.04 13.7 0.5 0.046 13.4 0.4 1.2 1 0 0 1 1 1 0 Predicted integral membrane protein (DUF2269) Spt20 PF12090.3 CDI82314.1 - 0.04 13.2 3.4 0.039 13.3 2.4 1.2 1 0 0 1 1 1 0 Spt20 family Nodulin-like PF06813.8 CDI82314.1 - 0.04 13.1 0.4 0.049 12.8 0.3 1.2 1 0 0 1 1 1 0 Nodulin-like MSC PF09402.5 CDI82314.1 - 0.041 12.5 5.3 0.044 12.5 3.7 1.1 1 0 0 1 1 1 0 Man1-Src1p-C-terminal domain OATP PF03137.15 CDI82314.1 - 0.045 11.8 0.4 0.045 11.8 0.3 1.2 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Ni_hydr_CYTB PF01292.15 CDI82314.1 - 0.047 13.0 0.3 0.078 12.3 0.2 1.5 1 1 0 1 1 1 0 Prokaryotic cytochrome b561 PIG-P PF08510.7 CDI82314.1 - 0.05 13.2 1.0 0.062 12.9 0.7 1.3 1 1 0 1 1 1 0 PIG-P Cas1_AcylT PF07779.7 CDI82314.1 - 0.056 11.9 2.0 0.058 11.8 1.4 1.0 1 0 0 1 1 1 0 10 TM Acyl Transferase domain found in Cas1p MscS_TM PF12794.2 CDI82314.1 - 0.057 12.0 7.7 0.065 11.8 5.4 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 DUF4245 PF14030.1 CDI82314.1 - 0.058 13.1 0.5 0.075 12.7 0.1 1.4 1 1 1 2 2 1 0 Protein of unknown function (DUF4245) FPN1 PF06963.7 CDI82314.1 - 0.058 11.7 0.5 0.063 11.6 0.3 1.1 1 0 0 1 1 1 0 Ferroportin1 (FPN1) DUF3959 PF13105.1 CDI82314.1 - 0.061 12.6 1.8 0.073 12.3 1.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3959) NfeD PF01957.13 CDI82314.1 - 0.064 13.4 0.0 0.069 13.2 0.0 1.2 1 0 0 1 1 1 0 NfeD-like C-terminal, partner-binding DUF1430 PF07242.6 CDI82314.1 - 0.068 13.2 1.1 0.097 12.7 0.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1430) Folate_carrier PF01770.13 CDI82314.1 - 0.069 11.6 1.4 0.082 11.4 1.0 1.2 1 0 0 1 1 1 0 Reduced folate carrier ABC_membrane PF00664.18 CDI82314.1 - 0.072 12.4 0.1 0.077 12.4 0.0 1.1 1 0 0 1 1 1 0 ABC transporter transmembrane region DUF443 PF04276.7 CDI82314.1 - 0.072 12.5 0.4 0.078 12.4 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF443) RseC_MucC PF04246.7 CDI82314.1 - 0.073 12.6 1.9 0.11 12.1 1.3 1.4 1 1 0 1 1 1 0 Positive regulator of sigma(E), RseC/MucC ATP-synt_8 PF00895.15 CDI82314.1 - 0.073 13.2 1.7 0.079 13.1 0.1 1.9 2 1 0 2 2 1 0 ATP synthase protein 8 Pox_P21 PF05313.7 CDI82314.1 - 0.075 12.2 0.3 0.084 12.1 0.2 1.1 1 0 0 1 1 1 0 Poxvirus P21 membrane protein Suf PF05843.9 CDI82314.1 - 0.077 12.7 5.6 0.07 12.8 3.9 1.0 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) PgaD PF13994.1 CDI82314.1 - 0.077 12.4 0.3 0.092 12.2 0.2 1.3 1 0 0 1 1 1 0 PgaD-like protein UPF0104 PF03706.8 CDI82314.1 - 0.082 12.1 0.0 0.082 12.1 0.0 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0104) ABC2_membrane_2 PF12679.2 CDI82314.1 - 0.091 11.6 0.5 0.1 11.4 0.4 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein DcuC PF03606.10 CDI82314.1 - 0.097 10.8 0.1 0.11 10.7 0.1 1.2 1 0 0 1 1 1 0 C4-dicarboxylate anaerobic carrier MFS_Mycoplasma PF07672.8 CDI82314.1 - 0.1 11.7 0.7 0.11 11.6 0.5 1.2 1 0 0 1 1 1 0 Mycoplasma MFS transporter O-ag_pol_Wzy PF14296.1 CDI82314.1 - 0.11 10.9 0.0 0.12 10.8 0.0 1.1 1 0 0 1 1 1 0 O-antigen polysaccharide polymerase Wzy MFS_2 PF13347.1 CDI82314.1 - 0.13 10.6 0.0 0.13 10.6 0.0 1.0 1 0 0 1 1 1 0 MFS/sugar transport protein DUF1345 PF07077.6 CDI82314.1 - 0.14 11.7 0.2 0.16 11.4 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1345) Stig1 PF04885.8 CDI82314.1 - 0.14 12.3 1.1 0.17 12.0 0.7 1.1 1 0 0 1 1 1 0 Stigma-specific protein, Stig1 Bap31 PF05529.7 CDI82314.1 - 0.14 11.5 8.0 0.19 11.1 5.5 1.2 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like K_trans PF02705.11 CDI82314.1 - 0.15 10.4 0.5 0.14 10.5 0.3 1.1 1 0 0 1 1 1 0 K+ potassium transporter Nucleoside_tran PF01733.13 CDI82314.1 - 0.15 11.1 0.5 0.16 11.0 0.4 1.1 1 0 0 1 1 1 0 Nucleoside transporter Neur_chan_memb PF02932.11 CDI82314.1 - 0.16 11.7 1.0 0.17 11.7 0.7 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Peroxin-13_N PF04088.8 CDI82314.1 - 0.19 11.6 1.5 0.21 11.5 1.0 1.1 1 0 0 1 1 1 0 Peroxin 13, N-terminal region RCR PF12273.3 CDI82314.1 - 0.29 11.6 14.5 0.68 10.5 10.1 1.6 1 1 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red HemY_N PF07219.8 CDI82314.1 - 0.36 10.4 3.2 0.16 11.5 0.9 1.4 1 1 1 2 2 2 0 HemY protein N-terminus DUF2215 PF10225.4 CDI82314.1 - 0.39 10.1 4.2 0.45 9.9 2.9 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) ALG3 PF05208.8 CDI82314.1 - 0.45 9.6 4.2 0.49 9.5 2.9 1.0 1 0 0 1 1 1 0 ALG3 protein OPA3 PF07047.7 CDI82314.1 - 0.51 10.1 10.1 0.56 9.9 7.0 1.1 1 0 0 1 1 1 0 Optic atrophy 3 protein (OPA3) PIRT PF15099.1 CDI82314.1 - 0.61 9.2 6.6 0.89 8.7 4.6 1.4 1 1 0 1 1 1 0 Phosphoinositide-interacting protein family ODV-E18 PF10717.4 CDI82314.1 - 0.71 9.3 4.9 0.38 10.2 2.2 1.7 1 1 1 2 2 2 0 Occlusion-derived virus envelope protein ODV-E18 Anoctamin PF04547.7 CDI82314.1 - 0.76 8.3 4.1 0.9 8.1 2.8 1.3 1 0 0 1 1 1 0 Calcium-activated chloride channel MLANA PF14991.1 CDI82314.1 - 0.76 9.8 3.8 0.14 12.1 0.2 1.6 1 1 1 2 2 1 0 Protein melan-A Endonuc_Holl PF10107.4 CDI82314.1 - 1.1 8.9 8.9 1.2 8.7 6.2 1.1 1 0 0 1 1 1 0 Endonuclease related to archaeal Holliday junction resolvase DUF2946 PF11162.3 CDI82314.1 - 2.1 8.5 4.7 4.1 7.6 3.3 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2946) DUF2270 PF10028.4 CDI82314.1 - 4.1 6.8 5.7 4.3 6.7 4.0 1.3 1 1 0 1 1 1 0 Predicted integral membrane protein (DUF2270) ERF PF04404.7 CDI82314.1 - 7.2 6.1 13.9 7.9 5.9 9.6 1.1 1 0 0 1 1 1 0 ERF superfamily DUF3357 PF11837.3 CDI82316.1 - 0.0016 18.2 0.2 0.0022 17.7 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3357) DUF3115 PF11312.3 CDI82316.1 - 0.0022 16.9 0.9 0.0028 16.5 0.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3115) DUF2309 PF10070.4 CDI82316.1 - 0.0093 14.1 0.6 0.0095 14.0 0.4 1.0 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2309) Coiled-coil_56 PF09813.4 CDI82316.1 - 0.012 15.5 2.3 0.012 15.5 1.6 2.1 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 56 AAA_22 PF13401.1 CDI82316.1 - 0.018 15.2 1.2 0.03 14.4 0.8 1.3 1 0 0 1 1 1 0 AAA domain NAD_binding_8 PF13450.1 CDI82316.1 - 0.023 14.6 0.2 0.055 13.5 0.1 1.7 1 1 0 1 1 1 0 NAD(P)-binding Rossmann-like domain DUF605 PF04652.11 CDI82316.1 - 0.075 12.4 9.8 0.1 11.9 6.8 1.2 1 0 0 1 1 1 0 Vta1 like Topoisom_I_N PF02919.10 CDI82316.1 - 0.081 12.2 2.5 1.9 7.7 0.4 2.0 2 0 0 2 2 2 0 Eukaryotic DNA topoisomerase I, DNA binding fragment DUF4647 PF15504.1 CDI82316.1 - 0.094 11.5 9.9 0.12 11.2 6.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4647) Rrn6 PF10214.4 CDI82316.1 - 0.11 10.5 8.9 0.13 10.3 6.2 1.0 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor NAD_binding_9 PF13454.1 CDI82316.1 - 0.18 11.5 0.2 0.18 11.5 0.1 2.9 3 1 0 3 3 2 0 FAD-NAD(P)-binding DDE_3 PF13358.1 CDI82316.1 - 0.27 10.9 2.4 0.36 10.5 1.7 1.1 1 0 0 1 1 1 0 DDE superfamily endonuclease Activator_LAG-3 PF11498.3 CDI82316.1 - 0.31 9.7 48.1 0.38 9.4 33.3 1.0 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Nha1_C PF08619.5 CDI82316.1 - 0.46 9.7 7.1 0.56 9.4 4.9 1.1 1 0 0 1 1 1 0 Alkali metal cation/H+ antiporter Nha1 C terminus DUF2489 PF10675.4 CDI82316.1 - 0.67 9.6 22.1 0.097 12.3 2.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2489) 7TM_GPCR_Srv PF10323.4 CDI82316.1 - 0.73 8.9 8.3 1.4 7.9 5.7 1.5 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srv CIAPIN1 PF05093.8 CDI82316.1 - 0.77 9.8 5.2 9.1 6.4 0.1 2.1 2 0 0 2 2 2 0 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis DUF2722 PF10846.3 CDI82316.1 - 0.85 8.5 17.2 0.045 12.7 0.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) DDHD PF02862.12 CDI82316.1 - 1.1 9.0 6.0 1.6 8.4 4.1 1.2 1 0 0 1 1 1 0 DDHD domain AAA_23 PF13476.1 CDI82316.1 - 1.2 9.4 12.0 2 8.7 8.3 1.3 1 0 0 1 1 1 0 AAA domain Pex14_N PF04695.8 CDI82316.1 - 1.2 9.1 22.1 0.055 13.5 4.2 2.1 1 1 1 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region RRN9 PF10680.4 CDI82316.1 - 1.2 8.8 0.0 1.2 8.8 0.0 2.3 2 0 0 2 2 2 0 RNA polymerase I specific transcription initiation factor 2-Hacid_dh_C PF02826.14 CDI82316.1 - 1.3 8.1 3.7 3.2 6.8 2.6 1.5 1 1 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Neur_chan_memb PF02932.11 CDI82316.1 - 1.3 8.8 5.0 1.8 8.3 3.4 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Rpp20 PF12328.3 CDI82316.1 - 1.5 8.4 9.5 2.6 7.7 0.7 2.2 2 0 0 2 2 2 0 Rpp20 subunit of nuclear RNase MRP and P Baculo_PP31 PF05311.6 CDI82316.1 - 1.5 7.9 8.8 2 7.6 6.1 1.1 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) PAT1 PF09770.4 CDI82316.1 - 2 6.5 29.0 2.5 6.2 20.1 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Ndc1_Nup PF09531.5 CDI82316.1 - 3.2 6.0 6.1 3.5 5.9 4.2 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF1764 PF08576.5 CDI82316.1 - 3.3 8.5 10.6 9.7 7.0 0.3 2.1 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF1764) Pyr_redox_2 PF07992.9 CDI82316.1 - 3.6 7.4 7.7 1.1 9.0 0.1 2.9 2 1 1 3 3 2 0 Pyridine nucleotide-disulphide oxidoreductase ATAD4 PF15321.1 CDI82316.1 - 3.7 8.6 10.1 7.5 7.6 0.2 2.1 2 0 0 2 2 2 0 ATPase family AAA domain containing 4 DUF243 PF03103.12 CDI82316.1 - 4.1 7.5 11.1 1.1 9.3 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF243) DUF912 PF06024.7 CDI82316.1 - 4.6 7.3 9.8 9.6 6.3 0.6 2.1 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) UPF0240 PF06784.6 CDI82316.1 - 5.5 6.6 9.5 0.86 9.2 0.5 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0240) FCP1_C PF09309.5 CDI82316.1 - 5.8 6.1 14.7 1.6 7.9 0.5 2.1 2 0 0 2 2 2 0 FCP1, C-terminal 7tm_1 PF00001.16 CDI82316.1 - 5.8 5.9 7.4 11 5.0 5.1 1.4 1 1 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) eIF-3_zeta PF05091.7 CDI82316.1 - 7.3 5.0 12.4 10 4.6 8.6 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF4660 PF15559.1 CDI82316.1 - 7.5 6.6 8.5 1.1 9.3 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4660) CagX PF03524.10 CDI82316.1 - 8.3 5.6 8.4 11 5.2 0.1 2.1 2 0 0 2 2 2 0 Conjugal transfer protein DUF3154 PF11351.3 CDI82316.1 - 9.7 5.9 13.4 13 5.5 3.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3154) Gly-zipper_OmpA PF13436.1 CDI82320.1 - 0.0005 19.7 7.1 0.0012 18.5 4.9 1.7 1 0 0 1 1 1 1 Glycine-zipper containing OmpA-like membrane domain BAF1_ABF1 PF04684.8 CDI82320.1 - 0.032 13.0 12.2 0.046 12.5 8.4 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Macoilin PF09726.4 CDI82320.1 - 0.055 11.7 8.8 0.074 11.3 6.1 1.1 1 0 0 1 1 1 0 Transmembrane protein Mcm10 PF09332.6 CDI82320.1 - 0.32 10.2 4.4 0.45 9.7 3.1 1.2 1 0 0 1 1 1 0 Mcm10 replication factor RR_TM4-6 PF06459.7 CDI82320.1 - 0.37 10.6 6.9 0.49 10.2 4.8 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 MSP1_C PF07462.6 CDI82320.1 - 4.1 5.6 4.6 5.2 5.3 3.2 1.2 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus PBP1_TM PF14812.1 CDI82324.1 - 0.023 14.9 2.2 0.023 14.9 1.5 3.1 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF4658 PF15555.1 CDI82324.1 - 0.041 13.7 0.9 0.078 12.8 0.2 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4658) CTI PF06934.6 CDI82324.1 - 0.18 10.0 14.5 0.23 9.6 10.0 1.1 1 0 0 1 1 1 0 Fatty acid cis/trans isomerase (CTI) PLRV_ORF5 PF01690.12 CDI82324.1 - 0.28 10.3 17.0 0.35 9.9 11.8 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein eIF-3_zeta PF05091.7 CDI82324.1 - 0.28 9.7 13.9 0.36 9.3 9.6 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) PAT1 PF09770.4 CDI82324.1 - 0.58 8.3 49.8 1.1 7.4 34.5 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF3533 PF12051.3 CDI82324.1 - 1.3 7.6 8.9 2.1 7.0 6.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3533) Shadoo PF14999.1 CDI82324.1 - 6.4 6.6 17.6 2.2 8.1 2.1 2.4 2 0 0 2 2 2 0 Shadow of prion protein, neuroprotective DUF4231 PF14015.1 CDI82324.1 - 6.9 6.7 10.7 0.54 10.2 1.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) Ndc1_Nup PF09531.5 CDI82324.1 - 8.8 4.6 12.3 13 4.0 8.5 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup RRM_5 PF13893.1 CDI82326.1 - 0.0011 18.7 0.0 0.0019 18.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CDI82326.1 - 0.0022 17.5 0.0 0.0054 16.3 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PNK3P PF08645.6 CDI82327.1 - 0.019 14.4 0.1 0.054 12.9 0.0 1.7 1 1 0 1 1 1 0 Polynucleotide kinase 3 phosphatase SR-25 PF10500.4 CDI82330.1 - 0.0093 15.4 6.0 0.0093 15.4 4.1 7.1 5 1 3 8 8 8 2 Nuclear RNA-splicing-associated protein Med15 PF09606.5 CDI82330.1 - 0.35 8.9 57.7 0.031 12.4 16.5 2.5 3 0 0 3 3 3 0 ARC105 or Med15 subunit of Mediator complex non-fungal Methyltransf_21 PF05050.7 CDI82330.1 - 8.3 6.3 6.5 4.5 7.1 1.5 2.7 1 1 1 2 2 2 0 Methyltransferase FkbM domain CAF-1_p150 PF11600.3 CDI82340.1 - 0.0021 17.4 39.4 0.0021 17.4 27.3 2.2 2 0 0 2 2 2 2 Chromatin assembly factor 1 complex p150 subunit, N-terminal FAP PF07174.6 CDI82340.1 - 0.0077 15.5 23.0 0.01 15.1 15.9 1.1 1 0 0 1 1 1 1 Fibronectin-attachment protein (FAP) SGT1 PF07093.6 CDI82340.1 - 0.014 13.7 35.9 0.018 13.4 24.9 1.1 1 0 0 1 1 1 0 SGT1 protein Nha1_C PF08619.5 CDI82340.1 - 0.19 10.9 49.3 0.1 11.8 18.7 2.0 2 0 0 2 2 2 0 Alkali metal cation/H+ antiporter Nha1 C terminus Ycf1 PF05758.7 CDI82340.1 - 1.4 6.5 49.5 0.05 11.3 5.6 2.1 2 0 0 2 2 2 0 Ycf1 Vfa1 PF08432.5 CDI82340.1 - 3.5 7.6 58.2 0.058 13.4 8.3 2.2 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 Herpes_UL87 PF03043.9 CDI82340.1 - 3.5 5.9 29.5 8.6 4.6 20.4 1.5 1 1 0 1 1 1 0 Herpesvirus UL87 family GAGA_bind PF06217.7 CDI82340.1 - 5.2 6.9 50.7 1.9 8.3 20.0 2.1 2 0 0 2 2 2 0 GAGA binding protein-like family CDK2AP PF09806.4 CDI82343.1 - 7.2e-05 23.1 6.0 7.2e-05 23.1 4.1 4.2 3 1 0 3 3 3 1 Cyclin-dependent kinase 2-associated protein Ribosomal_60s PF00428.14 CDI82343.1 - 0.1 12.9 28.8 0.97 9.8 2.9 3.3 3 0 0 3 3 3 0 60s Acidic ribosomal protein Phostensin_N PF13916.1 CDI82343.1 - 0.86 9.6 25.5 3.7 7.6 2.3 3.6 3 0 0 3 3 3 0 PP1-regulatory protein, Phostensin N-terminal Afi1 PF07792.7 CDI82343.1 - 2.9 7.8 19.4 0.02 14.9 3.6 2.9 1 1 1 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking DUF1180 PF06679.7 CDI82343.1 - 5.5 6.8 10.1 8.4 6.2 0.2 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1180) CcmD PF04995.9 CDI82343.1 - 6.4 6.5 19.7 2.3 8.0 1.5 3.9 3 0 0 3 3 3 0 Heme exporter protein D (CcmD) Conotoxin PF02950.12 CDI82343.1 - 9.7 7.0 23.9 1.5 9.6 1.1 4.7 5 0 0 5 5 5 0 Conotoxin RskA PF10099.4 CDI82343.1 - 9.9 5.8 34.8 0.037 13.7 5.3 4.0 1 1 3 4 4 4 0 Anti-sigma-K factor rskA DUF4184 PF13803.1 CDI82345.1 - 1.1 8.5 10.2 0.14 11.4 2.8 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4184) DUF1764 PF08576.5 CDI82346.1 - 1.6 9.5 25.3 2 9.2 17.5 1.2 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) SR-25 PF10500.4 CDI82346.1 - 8.1 5.8 21.5 9.5 5.6 14.9 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein PUF PF00806.14 CDI82347.1 - 4e-38 126.7 1.9 4.1e-07 29.1 0.0 6.3 6 0 0 6 6 6 6 Pumilio-family RNA binding repeat Pkinase PF00069.20 CDI82348.1 - 5.6e-33 114.1 0.0 1.5e-17 63.5 0.0 2.6 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CDI82348.1 - 1.6e-12 47.0 0.0 4.2e-06 26.0 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 CDI82348.1 - 1.2e-07 30.9 0.0 0.0041 16.1 0.1 2.5 2 0 0 2 2 2 2 Kinase-like Med15 PF09606.5 CDI82348.1 - 0.06 11.5 35.4 0.011 13.9 4.3 2.5 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF1764 PF08576.5 CDI82348.1 - 0.12 13.2 15.1 1.2 9.9 0.2 2.7 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF1764) TFIIA PF03153.8 CDI82348.1 - 0.31 10.8 21.4 0.37 10.6 6.6 2.5 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Suf PF05843.9 CDI82348.1 - 0.88 9.2 15.0 0.96 9.1 0.4 2.2 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) Spt20 PF12090.3 CDI82348.1 - 3 7.1 13.1 5.4 6.3 2.5 2.3 2 0 0 2 2 2 0 Spt20 family CagX PF03524.10 CDI82348.1 - 4.3 6.5 12.9 8.8 5.5 0.3 2.8 2 0 0 2 2 2 0 Conjugal transfer protein FimP PF09766.4 CDI82348.1 - 4.5 6.2 25.3 1.1 8.2 2.0 2.3 2 0 0 2 2 2 0 Fms-interacting protein Ctr PF04145.10 CDI82348.1 - 4.7 7.2 7.8 66 3.5 4.1 2.6 2 0 0 2 2 2 0 Ctr copper transporter family Band_3_cyto PF07565.8 CDI82348.1 - 7.4 5.9 11.1 37 3.7 0.0 2.2 2 0 0 2 2 2 0 Band 3 cytoplasmic domain DUF4647 PF15504.1 CDI82348.1 - 8.2 5.1 19.3 0.11 11.3 3.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4647) Neur_chan_memb PF02932.11 CDI82348.1 - 8.4 6.2 11.7 36 4.1 0.0 2.4 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region HXXEE PF13787.1 CDI82351.1 - 0.014 15.7 0.2 0.099 13.0 0.1 2.5 1 0 0 1 1 1 0 Protein of unknown function with HXXEE motif TMEM51 PF15345.1 CDI82362.1 - 0.0014 18.3 27.5 0.0018 18.0 19.1 1.2 1 0 0 1 1 1 1 Transmembrane protein 51 DUF3474 PF11960.3 CDI82362.1 - 0.48 10.4 14.1 0.094 12.7 6.9 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF3474) Herpes_env PF01673.13 CDI82362.1 - 4 5.8 20.2 4.7 5.6 14.0 1.0 1 0 0 1 1 1 0 Herpesvirus putative major envelope glycoprotein SR-25 PF10500.4 CDI82367.1 - 0.0064 15.9 22.5 0.008 15.6 15.6 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein TAF1D PF15333.1 CDI82367.1 - 0.031 14.0 7.8 0.042 13.6 5.4 1.3 1 0 0 1 1 1 0 TATA box-binding protein-associated factor 1D DUF4071 PF13281.1 CDI82367.1 - 0.048 12.5 4.1 0.054 12.3 2.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4071) DUF1645 PF07816.6 CDI82367.1 - 0.056 13.9 15.7 0.074 13.5 10.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1645) Cwf_Cwc_15 PF04889.7 CDI82367.1 - 0.069 12.8 9.9 0.094 12.4 6.9 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein CDK5_activator PF03261.10 CDI82367.1 - 0.081 12.2 8.9 0.094 12.0 6.2 1.0 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein Herpes_UL87 PF03043.9 CDI82367.1 - 0.29 9.4 7.8 0.33 9.2 5.4 1.1 1 0 0 1 1 1 0 Herpesvirus UL87 family Dynamin_N PF00350.18 CDI82367.1 - 0.31 10.8 4.9 0.83 9.4 3.4 1.6 1 1 0 1 1 1 0 Dynamin family Parvo_coat PF00740.13 CDI82367.1 - 0.44 9.4 7.4 0.54 9.1 5.1 1.0 1 0 0 1 1 1 0 Parvovirus coat protein VP2 DUF342 PF03961.8 CDI82367.1 - 0.63 8.3 2.8 0.73 8.1 1.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF972 PF06156.8 CDI82367.1 - 0.74 10.1 4.9 1.4 9.3 3.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF972) MSP1_C PF07462.6 CDI82367.1 - 0.77 8.0 7.4 0.91 7.8 5.1 1.2 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus DUF4632 PF15451.1 CDI82367.1 - 1 9.3 4.2 1.2 9.1 0.4 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4632) Suf PF05843.9 CDI82367.1 - 1.2 8.7 9.8 1.4 8.6 6.8 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Hex_IIIa PF02455.11 CDI82367.1 - 1.4 7.5 10.9 1.6 7.3 7.6 1.0 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) Pinin_SDK_memA PF04696.8 CDI82367.1 - 1.4 8.5 14.8 2.6 7.6 10.2 1.4 1 0 0 1 1 1 0 pinin/SDK/memA/ protein conserved region ZYG-11_interact PF05884.7 CDI82367.1 - 1.5 7.8 6.4 2.2 7.3 4.4 1.3 1 0 0 1 1 1 0 Interactor of ZYG-11 DUF4207 PF13904.1 CDI82367.1 - 1.7 7.9 21.5 2.2 7.5 14.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4207) RR_TM4-6 PF06459.7 CDI82367.1 - 1.9 8.3 7.5 2.5 7.8 5.2 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 YlqD PF11068.3 CDI82367.1 - 2 8.4 15.2 0.5 10.3 8.5 1.5 2 0 0 2 2 1 0 YlqD protein GvpL_GvpF PF06386.6 CDI82367.1 - 2.1 7.8 14.8 1.1 8.8 8.8 1.5 1 1 1 2 2 2 0 Gas vesicle synthesis protein GvpL/GvpF Peptidase_S46 PF10459.4 CDI82367.1 - 2.6 6.3 10.8 3 6.1 7.5 1.0 1 0 0 1 1 1 0 Peptidase S46 SOBP PF15279.1 CDI82367.1 - 2.8 8.2 11.2 3.1 8.0 7.8 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein Apt1 PF10351.4 CDI82367.1 - 3 6.5 9.6 3.2 6.5 6.6 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain GET2 PF08690.5 CDI82367.1 - 3.5 6.7 10.7 4.4 6.4 7.4 1.1 1 0 0 1 1 1 0 GET complex subunit GET2 TFIIA PF03153.8 CDI82367.1 - 4.6 7.0 16.7 5.9 6.6 11.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CAF-1_p150 PF11600.3 CDI82367.1 - 9 5.6 20.1 0.29 10.4 9.9 1.5 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal FUSC PF04632.7 CDI82367.1 - 9.2 4.5 20.3 13 4.0 14.1 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family MIP-T3 PF10243.4 CDI82371.1 - 0.00014 20.4 98.1 0.00018 20.1 68.0 1.2 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 Utp14 PF04615.8 CDI82371.1 - 1.5 6.9 100.1 1.9 6.5 69.4 1.1 1 0 0 1 1 1 0 Utp14 protein VIT1 PF01988.14 CDI82385.1 - 0.0088 15.5 1.9 0.0088 15.5 1.3 4.1 2 1 1 3 3 3 1 VIT family SAGA-Tad1 PF12767.2 CDI82385.1 - 0.48 10.0 55.9 0.54 9.8 2.9 3.2 3 0 0 3 3 3 0 Transcriptional regulator of RNA polII, SAGA, subunit FAM60A PF15396.1 CDI82385.1 - 5.3 6.7 41.6 1 9.0 0.3 3.3 3 0 0 3 3 3 0 Protein Family FAM60A GAGA_bind PF06217.7 CDI82385.1 - 7.6 6.3 47.8 5.9 6.7 16.0 3.3 3 0 0 3 3 3 0 GAGA binding protein-like family Apt1 PF10351.4 CDI82387.1 - 0.0041 16.0 0.6 0.0054 15.6 0.4 1.2 1 0 0 1 1 1 1 Golgi-body localisation protein domain DUF2076 PF09849.4 CDI82387.1 - 0.0074 16.3 14.3 0.0074 16.3 9.9 3.9 3 1 1 4 4 4 1 Uncharacterized protein conserved in bacteria (DUF2076) Gti1_Pac2 PF09729.4 CDI82387.1 - 0.042 13.7 0.7 3.8 7.3 0.3 2.3 2 0 0 2 2 2 0 Gti1/Pac2 family SR-25 PF10500.4 CDI82387.1 - 0.11 11.8 19.4 0.72 9.2 0.9 2.4 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Neur_chan_memb PF02932.11 CDI82387.1 - 0.13 12.0 0.9 0.23 11.3 0.4 1.6 1 1 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Serinc PF03348.10 CDI82387.1 - 1.3 7.6 3.8 2.3 6.8 2.6 1.4 1 0 0 1 1 1 0 Serine incorporator (Serinc) DUF912 PF06024.7 CDI82387.1 - 1.6 8.8 4.0 3.9 7.5 1.5 2.3 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Pex14_N PF04695.8 CDI82387.1 - 6.9 6.7 29.0 0.11 12.5 6.3 4.0 4 0 0 4 4 4 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Utp14 PF04615.8 CDI82393.1 - 4.5 5.3 78.3 5.6 4.9 54.3 1.1 1 0 0 1 1 1 0 Utp14 protein adh_short PF00106.20 CDI82396.1 - 8.3e-35 120.1 3.7 1.8e-34 119.0 2.4 1.7 2 0 0 2 2 2 1 short chain dehydrogenase SCP2 PF02036.12 CDI82396.1 - 1.7e-32 111.7 0.0 5.5e-15 55.5 0.0 2.5 2 0 0 2 2 2 2 SCP-2 sterol transfer family KR PF08659.5 CDI82396.1 - 1.8e-16 60.3 1.1 3.2e-16 59.5 0.8 1.4 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 CDI82396.1 - 9.8e-14 51.6 0.0 1.3e-12 47.9 0.1 2.1 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase UPF0564 PF10595.4 CDI82396.1 - 0.007 15.3 1.1 0.0092 14.9 0.7 1.2 1 0 0 1 1 1 1 Uncharacterised protein family UPF0564 Alkyl_sulf_C PF14864.1 CDI82396.1 - 0.01 15.7 0.0 4.9 7.1 0.0 2.5 2 0 0 2 2 2 0 Alkyl sulfatase C-terminal Maf_N PF08383.6 CDI82396.1 - 0.024 14.1 0.0 0.059 12.9 0.0 1.6 1 0 0 1 1 1 0 Maf N-terminal region DUF566 PF04484.7 CDI82410.1 - 0.7 9.3 5.8 0.79 9.1 4.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF566) DUF3373 PF11853.3 CDI82411.1 - 0.4 9.1 1.9 0.6 8.5 1.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) Peptidase_C58 PF03543.9 CDI82411.1 - 2.4 7.6 13.2 4 6.8 9.1 1.3 1 0 0 1 1 1 0 Yersinia/Haemophilus virulence surface antigen DUF4557 PF15101.1 CDI82411.1 - 5.4 6.8 16.1 0.75 9.6 8.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4557) Glyco_transf_15 PF01793.11 CDI82411.1 - 9.9 4.9 6.1 14 4.4 4.2 1.2 1 0 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase FYDLN_acid PF09538.5 CDI82415.1 - 0.27 11.8 4.6 0.31 11.6 3.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) Androgen_recep PF02166.11 CDI82415.1 - 0.29 9.9 3.9 0.38 9.5 2.7 1.1 1 0 0 1 1 1 0 Androgen receptor YqfQ PF14181.1 CDI82415.1 - 0.54 10.2 9.2 0.69 9.9 6.3 1.2 1 0 0 1 1 1 0 YqfQ-like protein Calc_CGRP_IAPP PF00214.14 CDI82415.1 - 0.87 9.6 4.5 0.92 9.5 3.1 1.1 1 0 0 1 1 1 0 Calcitonin / CGRP / IAPP family DUF4391 PF14335.1 CDI82415.1 - 1.1 8.5 10.5 1.1 8.5 7.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4391) DUF3138 PF11336.3 CDI82415.1 - 1.7 6.7 8.8 1.9 6.5 6.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Adeno_PIX PF03955.9 CDI82415.1 - 1.8 9.1 6.4 2.1 8.9 4.4 1.2 1 0 0 1 1 1 0 Adenovirus hexon-associated protein (IX) R_equi_Vir PF05526.6 CDI82415.1 - 2.1 7.9 5.0 1.9 8.0 3.5 1.0 1 0 0 1 1 1 0 Rhodococcus equi virulence-associated protein DUF3752 PF12572.3 CDI82415.1 - 2.3 8.3 13.2 2.5 8.2 9.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3752) Bap31 PF05529.7 CDI82415.1 - 4.3 6.7 11.0 4.9 6.5 7.6 1.0 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like Ribosomal_60s PF00428.14 CDI82415.1 - 4.4 7.7 24.3 8.3 6.8 16.9 1.6 1 1 0 1 1 1 0 60s Acidic ribosomal protein DUF3597 PF12200.3 CDI82415.1 - 4.8 7.5 9.9 5.9 7.3 6.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3597) DOR PF14839.1 CDI82415.1 - 7.5 6.2 10.9 7.7 6.1 7.5 1.0 1 0 0 1 1 1 0 DOR family IncA PF04156.9 CDI82417.1 - 2.2e-06 27.4 11.6 2.6e-06 27.1 8.0 1.1 1 0 0 1 1 1 1 IncA protein DUF1510 PF07423.6 CDI82417.1 - 0.00017 21.0 8.9 0.0002 20.7 6.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) Shisa PF13908.1 CDI82417.1 - 0.00038 20.6 9.0 0.00049 20.3 6.3 1.2 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator Neur_chan_memb PF02932.11 CDI82417.1 - 0.00044 20.2 5.9 0.0005 20.0 4.1 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Ctr PF04145.10 CDI82417.1 - 0.00046 20.2 2.4 0.00051 20.1 1.5 1.2 1 1 0 1 1 1 1 Ctr copper transporter family FimP PF09766.4 CDI82417.1 - 0.001 18.2 9.2 0.001 18.2 6.4 1.0 1 0 0 1 1 1 1 Fms-interacting protein FAM176 PF14851.1 CDI82417.1 - 0.001 18.7 0.6 0.0011 18.6 0.4 1.0 1 0 0 1 1 1 1 FAM176 family SID-1_RNA_chan PF13965.1 CDI82417.1 - 0.0012 17.1 3.1 0.0012 17.1 2.2 1.0 1 0 0 1 1 1 1 dsRNA-gated channel SID-1 SP_C-Propep PF08999.5 CDI82417.1 - 0.0012 18.2 0.3 0.0013 18.1 0.2 1.3 1 0 0 1 1 1 1 Surfactant protein C, N terminal propeptide OSTbeta PF15048.1 CDI82417.1 - 0.0027 17.7 5.4 0.0033 17.4 3.7 1.3 1 0 0 1 1 1 1 Organic solute transporter subunit beta protein Protocadherin PF08374.6 CDI82417.1 - 0.003 17.2 9.4 0.0033 17.0 6.5 1.1 1 0 0 1 1 1 1 Protocadherin DUF92 PF01940.11 CDI82417.1 - 0.0041 16.2 1.0 0.0053 15.9 0.7 1.1 1 0 0 1 1 1 1 Integral membrane protein DUF92 Choline_transpo PF04515.7 CDI82417.1 - 0.0041 15.9 0.5 0.0043 15.8 0.3 1.1 1 0 0 1 1 1 1 Plasma-membrane choline transporter DUF3366 PF11846.3 CDI82417.1 - 0.0048 16.8 4.7 0.0064 16.3 3.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3366) Flavi_NS4A PF01350.12 CDI82417.1 - 0.005 16.3 2.5 0.008 15.7 1.7 1.3 1 0 0 1 1 1 1 Flavivirus non-structural protein NS4A 7tm_1 PF00001.16 CDI82417.1 - 0.0065 15.6 1.7 0.0074 15.4 1.2 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) YjgP_YjgQ PF03739.9 CDI82417.1 - 0.0065 15.2 0.4 0.0074 15.0 0.3 1.1 1 0 0 1 1 1 1 Predicted permease YjgP/YjgQ family FHIPEP PF00771.15 CDI82417.1 - 0.0067 14.8 7.9 0.0074 14.6 5.4 1.0 1 0 0 1 1 1 1 FHIPEP family DUF4446 PF14584.1 CDI82417.1 - 0.0068 16.2 4.7 0.0089 15.8 3.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4446) SecY PF00344.15 CDI82417.1 - 0.0082 15.1 2.3 0.0089 14.9 1.6 1.1 1 0 0 1 1 1 1 SecY translocase DUF3609 PF12259.3 CDI82417.1 - 0.0092 14.6 5.7 0.0096 14.6 3.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3609) MFS_Mycoplasma PF07672.8 CDI82417.1 - 0.0093 15.1 1.6 0.011 14.8 1.1 1.2 1 0 0 1 1 1 1 Mycoplasma MFS transporter DUF4355 PF14265.1 CDI82417.1 - 0.0097 15.8 9.9 0.011 15.6 6.8 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4355) YfhO PF09586.5 CDI82417.1 - 0.01 13.8 5.0 0.0099 13.9 3.5 1.0 1 0 0 1 1 1 0 Bacterial membrane protein YfhO DUF3357 PF11837.3 CDI82417.1 - 0.01 15.6 5.5 0.02 14.7 3.8 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF3357) OPA3 PF07047.7 CDI82417.1 - 0.011 15.5 7.7 0.011 15.5 5.3 1.1 1 0 0 1 1 1 0 Optic atrophy 3 protein (OPA3) Zn_peptidase PF04228.8 CDI82417.1 - 0.012 14.8 7.3 0.014 14.6 5.0 1.2 1 0 0 1 1 1 0 Putative neutral zinc metallopeptidase DUF2371 PF10177.4 CDI82417.1 - 0.013 15.3 2.8 0.015 15.1 1.9 1.1 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2371) Cytochrom_B_N PF00033.14 CDI82417.1 - 0.016 14.5 0.1 0.019 14.3 0.0 1.1 1 0 0 1 1 1 0 Cytochrome b(N-terminal)/b6/petB TMEM51 PF15345.1 CDI82417.1 - 0.016 14.8 11.2 0.017 14.8 7.8 1.1 1 0 0 1 1 1 0 Transmembrane protein 51 Nucleoside_tran PF01733.13 CDI82417.1 - 0.017 14.3 2.5 0.018 14.2 1.7 1.0 1 0 0 1 1 1 0 Nucleoside transporter FPN1 PF06963.7 CDI82417.1 - 0.017 13.5 4.2 0.018 13.4 2.9 1.0 1 0 0 1 1 1 0 Ferroportin1 (FPN1) DUF2062 PF09835.4 CDI82417.1 - 0.019 14.6 0.0 0.023 14.3 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) DUF4367 PF14285.1 CDI82417.1 - 0.02 14.2 5.2 0.024 13.9 3.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4367) DUF3260 PF11658.3 CDI82417.1 - 0.021 13.0 10.4 0.022 12.9 7.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3260) Tetraspannin PF00335.15 CDI82417.1 - 0.021 14.1 0.8 0.023 14.0 0.5 1.2 1 0 0 1 1 1 0 Tetraspanin family Ni_hydr_CYTB PF01292.15 CDI82417.1 - 0.023 14.1 0.1 0.026 13.9 0.1 1.2 1 0 0 1 1 1 0 Prokaryotic cytochrome b561 CD20 PF04103.10 CDI82417.1 - 0.023 14.6 2.8 0.036 14.0 2.0 1.5 1 1 0 1 1 1 0 CD20-like family Trp_oprn_chp PF09534.5 CDI82417.1 - 0.024 14.2 13.8 0.037 13.6 9.6 1.3 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Herpes_glycop PF01528.11 CDI82417.1 - 0.025 13.2 8.5 0.028 13.1 5.9 1.0 1 0 0 1 1 1 0 Herpesvirus glycoprotein M DUF4199 PF13858.1 CDI82417.1 - 0.031 14.2 4.6 0.039 13.8 3.2 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF4199) GRP PF07172.6 CDI82417.1 - 0.032 14.7 1.7 0.044 14.2 1.2 1.3 1 0 0 1 1 1 0 Glycine rich protein family DUF929 PF06053.6 CDI82417.1 - 0.034 13.2 6.1 0.032 13.3 3.9 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF929) 60KD_IMP PF02096.15 CDI82417.1 - 0.036 13.7 12.6 0.046 13.3 8.7 1.1 1 0 0 1 1 1 0 60Kd inner membrane protein SHR3_chaperone PF08229.6 CDI82417.1 - 0.037 12.9 13.8 0.039 12.9 9.6 1.1 1 0 0 1 1 1 0 ER membrane protein SH3 SoxE PF06525.6 CDI82417.1 - 0.038 13.2 0.3 0.05 12.8 0.2 1.2 1 0 0 1 1 1 0 Sulfocyanin (SoxE) DUF3487 PF11990.3 CDI82417.1 - 0.038 13.3 0.1 0.046 13.1 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3487) DUF106 PF01956.11 CDI82417.1 - 0.041 13.4 5.4 0.048 13.2 3.8 1.1 1 0 0 1 1 1 0 Integral membrane protein DUF106 DUF2324 PF10086.4 CDI82417.1 - 0.045 12.9 5.9 0.053 12.7 4.1 1.3 1 0 0 1 1 1 0 Putative membrane peptidase family (DUF2324) Mem_trans PF03547.13 CDI82417.1 - 0.046 12.0 2.9 0.047 11.9 2.0 1.1 1 0 0 1 1 1 0 Membrane transport protein DcuC PF03606.10 CDI82417.1 - 0.047 11.9 7.1 0.053 11.7 4.9 1.0 1 0 0 1 1 1 0 C4-dicarboxylate anaerobic carrier Serinc PF03348.10 CDI82417.1 - 0.048 12.3 9.0 0.049 12.3 6.3 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) LRR19-TM PF15176.1 CDI82417.1 - 0.054 13.1 0.5 0.062 12.9 0.3 1.2 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain DUF819 PF05684.7 CDI82417.1 - 0.058 12.2 6.5 0.069 11.9 4.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF819) Neur PF00064.13 CDI82417.1 - 0.072 11.1 4.3 0.078 11.0 3.0 1.0 1 0 0 1 1 1 0 Neuraminidase DUF2899 PF11449.3 CDI82417.1 - 0.074 12.2 4.2 0.085 12.0 2.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2899) DUF2232 PF09991.4 CDI82417.1 - 0.075 12.0 7.2 0.081 11.9 5.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) DUF2140 PF09911.4 CDI82417.1 - 0.079 12.1 4.2 0.11 11.6 2.9 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2140) Dpy19 PF10034.4 CDI82417.1 - 0.081 11.0 2.9 0.084 11.0 2.0 1.0 1 0 0 1 1 1 0 Q-cell neuroblast polarisation DUF3278 PF11683.3 CDI82417.1 - 0.091 12.7 0.4 0.11 12.5 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3278) DUF897 PF05982.7 CDI82417.1 - 0.11 11.3 6.5 0.12 11.1 4.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF897) Herpes_UL4 PF03277.8 CDI82417.1 - 0.11 11.6 5.8 0.12 11.5 4.0 1.1 1 0 0 1 1 1 0 Herpesvirus UL4 family Suf PF05843.9 CDI82417.1 - 0.12 12.0 9.3 0.1 12.2 6.4 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Shadoo PF14999.1 CDI82417.1 - 0.13 12.1 4.2 0.13 12.1 2.9 1.2 1 0 0 1 1 1 0 Shadow of prion protein, neuroprotective COPI_assoc PF08507.5 CDI82417.1 - 0.13 11.8 0.1 0.16 11.6 0.1 1.1 1 0 0 1 1 1 0 COPI associated protein DUF3007 PF11460.3 CDI82417.1 - 0.13 12.2 8.8 0.16 12.0 6.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3007) DivIC PF04977.10 CDI82417.1 - 0.18 11.3 15.9 0.32 10.5 11.0 1.5 1 0 0 1 1 1 0 Septum formation initiator Stig1 PF04885.8 CDI82417.1 - 0.18 12.0 4.1 0.25 11.5 2.9 1.2 1 0 0 1 1 1 0 Stigma-specific protein, Stig1 V_ATPase_I PF01496.14 CDI82417.1 - 0.18 9.5 7.3 0.2 9.4 5.0 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4231 PF14015.1 CDI82417.1 - 0.2 11.6 5.5 0.25 11.3 3.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4231) EphA2_TM PF14575.1 CDI82417.1 - 0.24 11.7 19.4 2.2 8.7 13.5 2.1 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF1418 PF07214.7 CDI82417.1 - 0.3 10.7 3.6 0.38 10.4 2.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1418) Brr6_like_C_C PF10104.4 CDI82417.1 - 0.3 10.6 2.5 0.4 10.1 1.8 1.3 1 0 0 1 1 1 0 Di-sulfide bridge nucleocytoplasmic transport domain DUF1632 PF07857.7 CDI82417.1 - 0.32 10.2 2.5 0.34 10.1 1.8 1.1 1 0 0 1 1 1 0 CEO family (DUF1632) DUF4389 PF14333.1 CDI82417.1 - 0.37 10.5 3.9 0.52 10.0 2.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4389) Phage_holin_T PF11031.3 CDI82417.1 - 0.38 9.8 3.8 0.44 9.6 2.7 1.1 1 0 0 1 1 1 0 Bacteriophage T holin DUF2149 PF09919.4 CDI82417.1 - 0.44 10.6 8.1 0.57 10.3 5.6 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2149) MLANA PF14991.1 CDI82417.1 - 0.5 10.4 5.0 0.7 9.9 3.5 1.3 1 1 0 1 1 1 0 Protein melan-A DUF2217 PF10265.4 CDI82417.1 - 0.52 9.0 6.2 0.54 8.9 4.3 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) Herpes_gE PF02480.11 CDI82417.1 - 0.52 8.5 7.5 0.64 8.2 5.2 1.3 1 1 0 1 1 1 0 Alphaherpesvirus glycoprotein E HemY_N PF07219.8 CDI82417.1 - 0.53 9.8 8.7 1.3 8.6 6.0 1.8 1 1 0 1 1 1 0 HemY protein N-terminus Conotoxin PF02950.12 CDI82417.1 - 0.57 11.0 8.5 1.7 9.4 5.9 1.8 1 1 0 1 1 1 0 Conotoxin Pex16 PF08610.5 CDI82417.1 - 0.57 9.1 5.6 0.57 9.1 3.9 1.1 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) TraT PF05818.7 CDI82417.1 - 0.61 9.4 13.4 0.83 9.0 9.3 1.2 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein Peptidase_M56 PF05569.6 CDI82417.1 - 0.67 8.8 6.3 0.74 8.7 4.4 1.1 1 0 0 1 1 1 0 BlaR1 peptidase M56 DUF1183 PF06682.7 CDI82417.1 - 0.68 9.4 8.2 1.1 8.8 5.7 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1183) Endonuc_Holl PF10107.4 CDI82417.1 - 0.7 9.5 10.5 0.87 9.2 7.3 1.1 1 0 0 1 1 1 0 Endonuclease related to archaeal Holliday junction resolvase OppC_N PF12911.2 CDI82417.1 - 0.78 9.1 2.6 1.2 8.5 1.8 1.5 1 1 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C DUF2500 PF10694.4 CDI82417.1 - 0.8 9.7 10.0 1.1 9.2 7.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2500) 7TM_GPCR_Srv PF10323.4 CDI82417.1 - 0.95 8.5 5.9 1.2 8.2 4.1 1.3 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srv Cas1_AcylT PF07779.7 CDI82417.1 - 0.96 7.8 4.0 1.1 7.6 2.8 1.0 1 0 0 1 1 1 0 10 TM Acyl Transferase domain found in Cas1p DUF2215 PF10225.4 CDI82417.1 - 1.1 8.7 4.5 1.1 8.5 3.1 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) Chordopox_A13L PF05961.6 CDI82417.1 - 1.2 9.1 8.3 3.6 7.6 5.7 1.8 1 1 0 1 1 1 0 Chordopoxvirus A13L protein DUF4179 PF13786.1 CDI82417.1 - 1.7 8.9 6.3 4 7.7 4.4 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4179) TMEM154 PF15102.1 CDI82417.1 - 1.9 8.1 16.0 6.7 6.4 11.1 1.8 1 1 0 1 1 1 0 TMEM154 protein family Ribosomal_60s PF00428.14 CDI82417.1 - 2.4 8.6 15.3 4.9 7.6 10.6 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein HemX PF04375.9 CDI82417.1 - 2.5 6.5 24.9 2.9 6.3 17.2 1.0 1 0 0 1 1 1 0 HemX DUF1980 PF09323.5 CDI82417.1 - 2.8 7.6 6.5 3.4 7.3 4.5 1.2 1 1 0 1 1 1 0 Domain of unknown function (DUF1980) DUF4006 PF13179.1 CDI82417.1 - 2.9 7.5 13.7 3.6 7.1 9.1 1.5 1 1 0 1 1 1 0 Family of unknown function (DUF4006) Bac_luciferase PF00296.15 CDI82417.1 - 3.4 6.7 9.3 3.6 6.6 6.5 1.1 1 0 0 1 1 1 0 Luciferase-like monooxygenase Oligomerisation PF02410.10 CDI82417.1 - 3.8 7.6 7.4 4.4 7.3 5.1 1.1 1 0 0 1 1 1 0 Oligomerisation domain Helicase_RecD PF05127.9 CDI82417.1 - 3.9 7.0 11.1 4.6 6.8 7.7 1.0 1 0 0 1 1 1 0 Helicase FliP PF00813.15 CDI82417.1 - 4.9 6.8 7.2 5.4 6.6 5.0 1.1 1 0 0 1 1 1 0 FliP family R_equi_Vir PF05526.6 CDI82417.1 - 5.1 6.6 12.3 6.5 6.3 8.5 1.2 1 0 0 1 1 1 0 Rhodococcus equi virulence-associated protein Baculo_11_kDa PF06143.6 CDI82417.1 - 5.9 6.3 17.8 79 2.7 12.3 2.3 1 1 0 1 1 1 0 Baculovirus 11 kDa family FtsL PF04999.8 CDI82417.1 - 9.1 6.0 16.1 16 5.2 11.1 1.5 1 1 0 1 1 1 0 Cell division protein FtsL GOLD_2 PF13897.1 CDI82418.1 - 2.6 8.2 10.6 3.4 7.9 7.3 1.3 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking RNA_pol_Rpc4 PF05132.9 CDI82418.1 - 5.2 7.0 19.0 6.4 6.7 13.2 1.4 1 0 0 1 1 1 0 RNA polymerase III RPC4 Pox_Ag35 PF03286.9 CDI82418.1 - 6.4 6.2 17.6 6.9 6.1 12.2 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein FYDLN_acid PF09538.5 CDI82418.1 - 7.3 7.2 15.6 8.9 6.9 10.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) YqfQ PF14181.1 CDI82418.1 - 7.3 6.5 26.1 8.5 6.3 18.1 1.3 1 0 0 1 1 1 0 YqfQ-like protein AIF_C PF14721.1 CDI82418.1 - 7.8 6.7 18.8 9.4 6.4 13.0 1.3 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term DDHD PF02862.12 CDI82418.1 - 7.9 6.2 23.4 8.8 6.0 16.2 1.1 1 0 0 1 1 1 0 DDHD domain HSP90 PF00183.13 CDI82418.1 - 9.9 4.4 16.4 10 4.3 11.3 1.0 1 0 0 1 1 1 0 Hsp90 protein HGTP_anticodon2 PF12745.2 CDI82418.1 - 9.9 5.2 20.0 10 5.1 13.9 1.1 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs CDC45 PF02724.9 CDI82419.1 - 0.00023 19.3 27.9 0.00023 19.3 19.3 3.6 3 1 0 3 3 3 2 CDC45-like protein Neur_chan_memb PF02932.11 CDI82419.1 - 1 9.2 32.3 1.3 8.8 13.5 2.3 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region MIP-T3 PF10243.4 CDI82419.1 - 1.2 7.5 102.4 0.72 8.2 24.5 3.1 3 0 0 3 3 3 0 Microtubule-binding protein MIP-T3 DUF1183 PF06682.7 CDI82419.1 - 3.8 7.0 34.2 0.28 10.7 8.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1183) FimP PF09766.4 CDI82420.1 - 0.047 12.7 15.4 0.042 12.9 10.7 1.1 1 0 0 1 1 1 0 Fms-interacting protein PAT1 PF09770.4 CDI82420.1 - 0.054 11.7 24.0 0.053 11.7 16.6 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Suf PF05843.9 CDI82420.1 - 0.17 11.5 13.0 0.15 11.7 9.0 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Serinc PF03348.10 CDI82420.1 - 0.37 9.4 6.2 0.37 9.4 4.3 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) Gag_spuma PF03276.9 CDI82420.1 - 0.72 8.1 18.5 0.64 8.2 12.8 1.2 1 0 0 1 1 1 0 Spumavirus gag protein OATP PF03137.15 CDI82420.1 - 1.8 6.5 4.2 1.5 6.8 2.9 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family AAA_23 PF13476.1 CDI82420.1 - 2 8.7 11.8 2.1 8.6 8.2 1.2 1 0 0 1 1 1 0 AAA domain Shadoo PF14999.1 CDI82420.1 - 3.6 7.4 11.9 4.7 7.0 8.3 1.1 1 0 0 1 1 1 0 Shadow of prion protein, neuroprotective MutS_V PF00488.16 CDI82421.1 - 2e-34 119.0 5.2 2.2e-34 118.8 0.1 2.6 2 1 0 2 2 2 1 MutS domain V G-alpha PF00503.15 CDI82421.1 - 0.35 9.4 0.0 0.35 9.4 0.0 4.2 4 1 0 4 4 4 0 G-protein alpha subunit MACPF PF01823.14 CDI82424.1 - 1.7 8.3 10.1 1.7 8.3 7.0 1.0 1 0 0 1 1 1 0 MAC/Perforin domain DUF1517 PF07466.6 CDI82424.1 - 1.9 7.3 9.8 2.3 7.1 6.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) DUF1421 PF07223.6 CDI82424.1 - 2.5 7.7 8.6 2.4 7.8 6.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1421) Pex14_N PF04695.8 CDI82424.1 - 3.9 7.5 8.1 4.2 7.4 5.6 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF605 PF04652.11 CDI82424.1 - 4 6.7 8.2 4.3 6.6 5.7 1.0 1 0 0 1 1 1 0 Vta1 like APC_CDC26 PF10471.4 CDI82424.1 - 6.5 7.5 6.7 7.9 7.2 4.7 1.2 1 0 0 1 1 1 0 Anaphase-promoting complex APC subunit 1 ABC_ATPase PF09818.4 CDI82425.1 - 0.12 10.8 0.0 0.15 10.6 0.0 1.1 1 0 0 1 1 1 0 Predicted ATPase of the ABC class Dehydrin PF00257.14 CDI82426.1 - 0.016 15.5 5.8 0.016 15.5 4.0 3.6 4 0 0 4 4 4 0 Dehydrin Gag_p17 PF00540.13 CDI82426.1 - 0.16 11.7 0.2 0.16 11.7 0.1 2.2 2 0 0 2 2 2 0 gag gene protein p17 (matrix protein) SprA-related PF12118.3 CDI82426.1 - 1.9 7.7 27.9 2.6 7.2 19.3 1.3 1 1 0 1 1 1 0 SprA-related family DUF1777 PF08648.7 CDI82436.1 - 7.5e-05 22.5 58.8 7.5e-05 22.5 40.8 6.3 1 1 3 4 4 4 2 Protein of unknown function (DUF1777) SAPS PF04499.10 CDI82445.1 - 0.00034 19.3 20.6 0.0027 16.4 12.2 2.5 1 1 1 2 2 2 1 SIT4 phosphatase-associated protein Sporozoite_P67 PF05642.6 CDI82447.1 - 4.2e-06 24.9 0.8 0.054 11.3 0.0 2.7 1 1 0 2 2 2 1 Sporozoite P67 surface antigen DUF775 PF05603.7 CDI82447.1 - 0.0061 16.0 2.0 0.0061 16.0 1.4 5.7 5 1 0 5 5 5 1 Protein of unknown function (DUF775) zf-DHHC PF01529.15 CDI82447.1 - 2 7.7 15.5 3.8 6.8 0.0 4.1 4 0 0 4 4 4 0 DHHC palmitoyltransferase DUF4367 PF14285.1 CDI82448.1 - 0.46 9.7 0.0 0.46 9.7 0.0 8.1 10 1 0 10 10 10 0 Domain of unknown function (DUF4367) Utp14 PF04615.8 CDI82448.1 - 6.2 4.8 83.9 0.13 10.3 33.7 3.2 3 0 0 3 3 3 0 Utp14 protein DUF4557 PF15101.1 CDI82449.1 - 0.0014 18.5 14.4 0.0018 18.1 10.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4557) Suf PF05843.9 CDI82449.1 - 0.0045 16.7 13.5 0.0048 16.6 9.3 1.1 1 0 0 1 1 1 1 Suppressor of forked protein (Suf) FAM222A PF15258.1 CDI82449.1 - 0.0067 15.6 14.5 0.0083 15.3 10.0 1.1 1 0 0 1 1 1 1 Protein family of FAM222A Med15 PF09606.5 CDI82449.1 - 0.0083 14.3 30.9 0.0093 14.2 21.4 1.1 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal Hamartin PF04388.7 CDI82449.1 - 0.014 14.1 10.3 0.015 14.0 7.2 1.0 1 0 0 1 1 1 0 Hamartin protein FimP PF09766.4 CDI82449.1 - 0.017 14.2 17.5 0.022 13.8 12.1 1.1 1 0 0 1 1 1 0 Fms-interacting protein AAA_23 PF13476.1 CDI82449.1 - 0.019 15.2 4.3 0.018 15.3 3.0 1.1 1 0 0 1 1 1 0 AAA domain SprA-related PF12118.3 CDI82449.1 - 0.029 13.7 29.4 0.034 13.4 20.4 1.1 1 0 0 1 1 1 0 SprA-related family N6_N4_Mtase PF01555.13 CDI82449.1 - 0.042 13.3 0.2 0.048 13.1 0.1 1.1 1 0 0 1 1 1 0 DNA methylase UPF0560 PF10577.4 CDI82449.1 - 0.07 11.3 11.7 0.068 11.4 8.1 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 DUF908 PF06012.7 CDI82449.1 - 0.087 12.1 3.6 0.1 11.8 2.5 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) FLO_LFY PF01698.11 CDI82449.1 - 0.1 11.4 6.8 0.1 11.4 4.7 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein TraT PF05818.7 CDI82449.1 - 0.11 11.8 6.0 0.15 11.4 4.2 1.2 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein DDHD PF02862.12 CDI82449.1 - 0.14 11.9 10.6 0.18 11.5 7.3 1.1 1 0 0 1 1 1 0 DDHD domain Spore_coat_CotO PF14153.1 CDI82449.1 - 0.15 11.5 13.6 0.16 11.4 9.4 1.1 1 0 0 1 1 1 0 Spore coat protein CotO DUF3408 PF11888.3 CDI82449.1 - 0.17 11.8 7.8 0.2 11.5 5.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) Serinc PF03348.10 CDI82449.1 - 0.17 10.5 7.1 0.17 10.6 4.9 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) VIT1 PF01988.14 CDI82449.1 - 0.21 11.0 1.9 0.3 10.5 1.3 1.3 1 0 0 1 1 1 0 VIT family zf-DHHC PF01529.15 CDI82449.1 - 0.21 10.9 2.2 0.23 10.8 1.6 1.1 1 0 0 1 1 1 0 DHHC palmitoyltransferase DUF4175 PF13779.1 CDI82449.1 - 0.29 8.7 29.0 0.35 8.5 20.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) CDC27 PF09507.5 CDI82449.1 - 0.3 10.2 13.9 0.34 10.0 9.6 1.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Hid1 PF12722.2 CDI82449.1 - 0.31 8.6 6.5 0.3 8.7 4.5 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein PcfK PF14058.1 CDI82449.1 - 0.42 10.7 12.1 0.57 10.3 8.4 1.3 1 0 0 1 1 1 0 PcfK-like protein TFIIA PF03153.8 CDI82449.1 - 0.45 10.3 26.7 0.48 10.2 18.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF3381 PF11861.3 CDI82449.1 - 0.5 9.8 8.2 0.62 9.5 5.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) DUF4407 PF14362.1 CDI82449.1 - 0.54 9.1 13.1 0.53 9.1 9.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) RR_TM4-6 PF06459.7 CDI82449.1 - 0.58 10.0 10.5 0.65 9.8 7.3 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Herpes_glycop PF01528.11 CDI82449.1 - 0.58 8.7 2.7 0.62 8.6 1.8 1.0 1 0 0 1 1 1 0 Herpesvirus glycoprotein M AIF_C PF14721.1 CDI82449.1 - 0.6 10.3 9.3 0.85 9.8 6.4 1.3 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term DUF775 PF05603.7 CDI82449.1 - 0.61 9.5 10.6 0.68 9.4 7.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF775) DOR PF14839.1 CDI82449.1 - 0.81 9.3 18.5 1 9.0 12.9 1.1 1 0 0 1 1 1 0 DOR family OATP PF03137.15 CDI82449.1 - 0.82 7.6 5.5 0.9 7.5 3.8 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Paf1 PF03985.8 CDI82449.1 - 0.95 8.1 11.2 1.2 7.8 7.8 1.1 1 0 0 1 1 1 0 Paf1 R_equi_Vir PF05526.6 CDI82449.1 - 1.1 8.9 10.2 1.5 8.4 7.1 1.2 1 0 0 1 1 1 0 Rhodococcus equi virulence-associated protein Gag_spuma PF03276.9 CDI82449.1 - 1.2 7.4 23.3 1.5 7.0 16.2 1.1 1 0 0 1 1 1 0 Spumavirus gag protein Zip PF02535.17 CDI82449.1 - 1.3 7.9 4.2 1.4 7.8 2.9 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter eIF-3_zeta PF05091.7 CDI82449.1 - 1.4 7.4 12.4 1.6 7.2 8.6 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) AUX_IAA PF02309.11 CDI82449.1 - 1.6 8.4 8.0 1.8 8.2 5.6 1.2 1 0 0 1 1 1 0 AUX/IAA family PAT1 PF09770.4 CDI82449.1 - 1.7 6.7 32.6 1.7 6.7 22.6 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF1764 PF08576.5 CDI82449.1 - 1.7 9.4 12.4 2.6 8.8 8.6 1.4 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) DUF966 PF06136.8 CDI82449.1 - 1.7 7.9 12.6 2.4 7.4 8.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF966) DUF853 PF05872.7 CDI82449.1 - 1.9 6.7 10.4 2.1 6.6 7.2 1.0 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) Peptidase_S15 PF02129.13 CDI82449.1 - 1.9 7.8 10.9 3.1 7.1 7.6 1.3 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Neur_chan_memb PF02932.11 CDI82449.1 - 1.9 8.2 4.5 2 8.2 3.1 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region G0-G1_switch_2 PF15103.1 CDI82449.1 - 2.3 8.5 9.6 3.7 7.8 6.7 1.5 1 0 0 1 1 1 0 G0/G1 switch protein 2 Ndc1_Nup PF09531.5 CDI82449.1 - 2.6 6.3 7.7 2.5 6.4 5.3 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Baculo_PP31 PF05311.6 CDI82449.1 - 3.5 6.8 11.2 4 6.6 7.8 1.2 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) Peptidase_U57 PF05582.7 CDI82449.1 - 3.6 6.4 8.7 5.3 5.9 6.0 1.2 1 0 0 1 1 1 0 YabG peptidase U57 Med13_N PF11597.3 CDI82449.1 - 3.6 6.1 13.1 4.1 5.9 9.1 1.2 1 0 0 1 1 1 0 Mediator complex subunit 13 N-terminal DUF913 PF06025.7 CDI82449.1 - 4.1 6.0 7.6 4.4 5.9 5.3 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Herpes_DNAp_acc PF04929.7 CDI82449.1 - 4.2 6.2 9.0 4.6 6.1 6.3 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Band_3_cyto PF07565.8 CDI82449.1 - 4.6 6.6 12.1 6.1 6.2 8.4 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Presenilin PF01080.12 CDI82449.1 - 6.3 5.5 9.2 6.9 5.3 6.3 1.1 1 0 0 1 1 1 0 Presenilin EIIBC-GUT_N PF03612.9 CDI82449.1 - 6.7 6.2 8.7 8.8 5.9 6.0 1.3 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Folate_carrier PF01770.13 CDI82449.1 - 7.3 4.9 6.0 8.4 4.7 4.1 1.1 1 0 0 1 1 1 0 Reduced folate carrier Peptidase_S49_N PF08496.5 CDI82449.1 - 8.7 6.1 10.2 12 5.6 7.1 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Pex16 PF08610.5 CDI82449.1 - 9.4 5.1 13.4 56 2.5 10.2 1.5 2 0 0 2 2 2 0 Peroxisomal membrane protein (Pex16) DUF912 PF06024.7 CDI82449.1 - 9.4 6.3 8.7 7.6 6.6 5.2 1.6 2 0 0 2 2 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) RR_TM4-6 PF06459.7 CDI82465.1 - 0.19 11.5 21.2 0.2 11.5 14.7 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 TFIIA PF03153.8 CDI82465.1 - 0.37 10.6 39.7 0.37 10.6 27.5 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit BTV_NS2 PF04514.7 CDI82465.1 - 0.42 9.4 16.4 0.46 9.3 11.4 1.0 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 FNIP_N PF14636.1 CDI82465.1 - 1 9.8 20.1 1.3 9.5 13.9 1.3 1 0 0 1 1 1 0 Folliculin-interacting protein N-terminus Med19 PF10278.4 CDI82465.1 - 1 8.9 15.5 1.2 8.7 10.7 1.1 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 Pal1 PF08316.6 CDI82465.1 - 1.5 9.2 13.0 1.9 8.9 9.0 1.1 1 0 0 1 1 1 0 Pal1 cell morphology protein PPP4R2 PF09184.6 CDI82465.1 - 1.6 8.1 19.8 2 7.8 13.8 1.0 1 0 0 1 1 1 0 PPP4R2 Zip PF02535.17 CDI82465.1 - 1.9 7.4 10.5 2 7.3 7.3 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Med15 PF09606.5 CDI82465.1 - 2 6.5 76.3 2.2 6.3 52.9 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal AUX_IAA PF02309.11 CDI82465.1 - 2.6 7.7 18.0 3.2 7.4 12.5 1.1 1 0 0 1 1 1 0 AUX/IAA family Neur_chan_memb PF02932.11 CDI82465.1 - 3.1 7.6 15.2 3.1 7.6 10.5 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Tim54 PF11711.3 CDI82465.1 - 3.6 6.0 16.1 3.9 5.9 11.2 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DUF4045 PF13254.1 CDI82465.1 - 3.7 6.7 20.6 4.2 6.5 14.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) PAT1 PF09770.4 CDI82465.1 - 5.2 5.1 65.1 6.1 4.9 45.1 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF1510 PF07423.6 CDI82473.1 - 6.4 6.0 39.1 7.9 5.7 27.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) IncA PF04156.9 CDI82475.1 - 0.00066 19.3 15.6 0.00066 19.3 10.8 5.6 3 2 1 4 4 4 2 IncA protein TrbL PF04610.9 CDI82475.1 - 0.025 14.2 0.8 0.025 14.2 0.6 2.4 2 0 0 2 2 2 0 TrbL/VirB6 plasmid conjugal transfer protein FA_desaturase PF00487.19 CDI82475.1 - 0.16 11.4 8.0 0.24 10.7 0.1 2.3 2 0 0 2 2 2 0 Fatty acid desaturase DUF966 PF06136.8 CDI82476.1 - 4.6 6.5 23.4 5.3 6.3 16.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF966) SAGA-Tad1 PF12767.2 CDI82476.1 - 5.9 6.4 31.8 7 6.2 22.1 1.1 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit HSP70 PF00012.15 CDI82476.1 - 6.1 4.6 22.4 6.8 4.4 15.5 1.0 1 0 0 1 1 1 0 Hsp70 protein CDK2AP PF09806.4 CDI82476.1 - 7.7 6.6 23.4 10 6.3 16.2 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein DUF2076 PF09849.4 CDI82479.1 - 0.0042 17.1 7.5 0.0047 17.0 5.2 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) Fmp27_WPPW PF10359.4 CDI82479.1 - 0.011 14.2 2.4 0.011 14.2 1.6 1.0 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Fe_bilin_red PF05996.7 CDI82479.1 - 0.015 14.7 1.3 0.017 14.5 0.9 1.2 1 0 0 1 1 1 0 Ferredoxin-dependent bilin reductase DUF4407 PF14362.1 CDI82479.1 - 0.022 13.7 5.8 0.024 13.6 4.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Phasin PF05597.6 CDI82479.1 - 0.029 14.1 3.3 0.029 14.1 2.3 1.4 1 1 0 1 1 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) GlnD_UR_UTase PF08335.6 CDI82479.1 - 0.062 13.1 4.8 0.074 12.8 3.3 1.1 1 0 0 1 1 1 0 GlnD PII-uridylyltransferase PARG_cat PF05028.9 CDI82479.1 - 0.067 12.4 1.1 0.073 12.3 0.7 1.0 1 0 0 1 1 1 0 Poly (ADP-ribose) glycohydrolase (PARG) OmpH PF03938.9 CDI82479.1 - 0.069 13.0 12.9 0.086 12.7 9.0 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) zf-CpG_bind_C PF12269.3 CDI82479.1 - 0.081 12.3 2.9 0.093 12.1 2.0 1.1 1 0 0 1 1 1 0 CpG binding protein zinc finger C terminal domain CDC37_N PF03234.9 CDI82479.1 - 0.083 13.2 3.8 0.088 13.1 2.7 1.1 1 0 0 1 1 1 0 Cdc37 N terminal kinase binding Pol_alpha_B_N PF08418.5 CDI82479.1 - 0.084 12.3 2.1 0.091 12.2 1.5 1.1 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal IncA PF04156.9 CDI82479.1 - 0.089 12.3 13.1 0.11 12.0 9.1 1.2 1 0 0 1 1 1 0 IncA protein DUF3584 PF12128.3 CDI82479.1 - 0.11 9.8 7.6 0.1 9.9 5.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF3782 PF12644.2 CDI82479.1 - 0.14 11.9 2.2 0.19 11.5 1.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3782) DUF3482 PF11981.3 CDI82479.1 - 0.14 11.3 4.9 0.17 11.0 3.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3482) 7tm_6 PF02949.15 CDI82479.1 - 0.16 10.8 0.4 0.18 10.6 0.3 1.1 1 0 0 1 1 1 0 7tm Odorant receptor Spc24 PF08286.6 CDI82479.1 - 0.16 11.7 5.3 0.18 11.5 3.7 1.2 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 ACCA PF03255.9 CDI82479.1 - 0.17 11.4 1.1 0.17 11.4 0.8 1.1 1 0 0 1 1 1 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit NPV_P10 PF05531.7 CDI82479.1 - 0.19 12.0 6.0 0.23 11.7 4.0 1.3 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein GAS PF13851.1 CDI82479.1 - 0.23 10.6 10.8 0.27 10.3 7.5 1.1 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Syntaxin PF00804.20 CDI82479.1 - 0.23 11.6 7.7 0.32 11.1 5.4 1.2 1 0 0 1 1 1 0 Syntaxin DUF3505 PF12013.3 CDI82479.1 - 0.24 11.6 2.5 0.27 11.5 1.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3505) CR6_interact PF10147.4 CDI82479.1 - 0.26 10.5 7.1 0.31 10.3 4.9 1.1 1 0 0 1 1 1 0 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 YkuI_C PF10388.4 CDI82479.1 - 0.27 10.8 2.8 0.32 10.6 1.9 1.1 1 0 0 1 1 1 0 EAL-domain associated signalling protein domain EAP30 PF04157.11 CDI82479.1 - 0.3 10.1 6.6 0.32 10.1 4.6 1.1 1 0 0 1 1 1 0 EAP30/Vps36 family P4Ha_N PF08336.6 CDI82479.1 - 0.54 10.0 5.1 0.69 9.7 3.5 1.1 1 0 0 1 1 1 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region AAA_23 PF13476.1 CDI82479.1 - 1.1 9.5 6.5 1.1 9.5 4.5 1.1 1 0 0 1 1 1 0 AAA domain NUDE_C PF04880.8 CDI82479.1 - 1.1 9.6 4.4 1.3 9.4 3.1 1.0 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region Spc7 PF08317.6 CDI82479.1 - 1.7 7.2 8.7 1.8 7.1 6.0 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein H-kinase_dim PF02895.9 CDI82479.1 - 2.8 8.3 7.0 0.73 10.2 2.8 1.6 1 1 1 2 2 2 0 Signal transducing histidine kinase, homodimeric domain APG6 PF04111.7 CDI82479.1 - 5.2 6.0 10.9 5.7 5.8 7.6 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF4446 PF14584.1 CDI82479.1 - 5.6 6.7 6.0 7.1 6.4 4.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) DOR PF14839.1 CDI82479.1 - 8.7 6.0 8.6 11 5.6 6.0 1.1 1 0 0 1 1 1 0 DOR family TSA PF03249.8 CDI82479.1 - 9.3 4.6 8.9 9.3 4.6 6.2 1.1 1 0 0 1 1 1 0 Type specific antigen DDRGK PF09756.4 CDI82480.1 - 0.0056 16.1 10.5 0.0056 16.1 7.3 2.3 2 0 0 2 2 2 1 DDRGK domain NicO PF03824.11 CDI82480.1 - 2.9 7.1 5.8 3.7 6.7 3.8 1.3 1 1 0 1 1 1 0 High-affinity nickel-transport protein MACPF PF01823.14 CDI82482.1 - 0.28 10.8 6.0 0.079 12.6 0.3 2.0 2 0 0 2 2 2 0 MAC/Perforin domain PAT1 PF09770.4 CDI82484.1 - 7.8e-05 21.1 84.7 7.8e-05 21.1 58.7 5.0 4 1 0 4 4 4 1 Topoisomerase II-associated protein PAT1 Neur_chan_memb PF02932.11 CDI82484.1 - 5.1 6.9 0.0 5.1 6.9 0.0 4.5 4 2 1 5 5 5 0 Neurotransmitter-gated ion-channel transmembrane region Baculo_PP31 PF05311.6 CDI82485.1 - 0.12 11.6 5.1 22 4.1 4.9 2.3 2 0 0 2 2 2 0 Baculovirus 33KDa late protein (PP31) Pex14_N PF04695.8 CDI82485.1 - 0.51 10.3 19.4 0.087 12.8 4.4 2.7 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region RED_N PF07808.8 CDI82485.1 - 9.2 5.4 13.3 18 4.4 9.2 1.4 1 0 0 1 1 1 0 RED-like protein N-terminal region TcdA_TcdB_pore PF12920.2 CDI82486.1 - 0.56 8.0 7.1 0.92 7.3 4.9 1.2 1 0 0 1 1 1 0 TcdA/TcdB pore forming domain Yae1_N PF09811.4 CDI82488.1 - 5.5e-07 28.9 12.9 0.04 13.4 1.9 4.7 2 2 0 2 2 2 2 Essential protein Yae1, N terminal SR-25 PF10500.4 CDI82491.1 - 0.00046 19.7 4.9 0.00046 19.7 3.4 2.2 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein Bac_luciferase PF00296.15 CDI82491.1 - 0.015 14.4 8.3 0.32 10.0 5.8 2.1 1 1 0 1 1 1 0 Luciferase-like monooxygenase RE_XamI PF09572.5 CDI82491.1 - 0.073 12.5 0.2 0.073 12.5 0.1 1.9 2 1 1 3 3 3 0 XamI restriction endonuclease Gly-zipper_OmpA PF13436.1 CDI82491.1 - 0.083 12.5 24.2 0.026 14.1 5.8 2.5 2 0 0 2 2 2 0 Glycine-zipper containing OmpA-like membrane domain DUF3115 PF11312.3 CDI82491.1 - 0.11 11.3 2.6 0.3 9.8 2.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3115) Dehydrin PF00257.14 CDI82491.1 - 0.13 12.6 1.9 1.5 9.1 0.0 2.4 2 0 0 2 2 2 0 Dehydrin Phostensin_N PF13916.1 CDI82491.1 - 0.13 12.2 2.7 0.12 12.3 0.7 1.8 2 0 0 2 2 2 0 PP1-regulatory protein, Phostensin N-terminal Ribosomal_60s PF00428.14 CDI82491.1 - 0.14 12.5 32.5 0.76 10.2 5.1 2.6 2 0 0 2 2 2 0 60s Acidic ribosomal protein TraT PF05818.7 CDI82491.1 - 0.24 10.7 8.7 0.83 9.0 0.7 2.2 2 0 0 2 2 2 0 Enterobacterial TraT complement resistance protein APC_CDC26 PF10471.4 CDI82491.1 - 2.3 9.0 14.3 0.55 11.0 3.1 2.5 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit 1 DUF3995 PF13160.1 CDI82491.1 - 3.1 7.8 10.1 3.3 7.7 0.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3995) ASFV_J13L PF05568.6 CDI82491.1 - 4.9 6.6 13.6 1 8.8 0.7 2.4 2 0 0 2 2 2 0 African swine fever virus J13L protein Glyco_hydro_9 PF00759.14 CDI82491.1 - 8.8 5.1 14.3 0.12 11.2 0.1 2.1 2 0 0 2 2 2 0 Glycosyl hydrolase family 9 Activator_LAG-3 PF11498.3 CDI82494.1 - 8.5e-06 24.7 64.8 0.00015 20.6 29.5 2.8 2 0 0 2 2 2 2 Transcriptional activator LAG-3 LicD PF04991.8 CDI82494.1 - 1.7 8.6 3.1 3.5 7.6 2.2 1.4 1 0 0 1 1 1 0 LicD family DRY_EERY PF09750.4 CDI82494.1 - 4.9 7.2 21.4 13 5.9 0.1 3.2 2 0 0 2 2 2 0 Alternative splicing regulator AAA_23 PF13476.1 CDI82494.1 - 6.6 7.0 28.6 0.46 10.7 11.7 2.2 2 0 0 2 2 2 0 AAA domain FAM91_C PF14648.1 CDI82500.1 - 0.78 8.5 7.0 0.78 8.5 4.8 1.0 1 0 0 1 1 1 0 FAM91 C-terminus Band_3_cyto PF07565.8 CDI82500.1 - 1.2 8.5 18.1 1.2 8.5 12.5 1.0 1 0 0 1 1 1 0 Band 3 cytoplasmic domain DUF3449 PF11931.3 CDI82500.1 - 1.2 8.5 18.7 1.4 8.4 12.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3449) Pox_Ag35 PF03286.9 CDI82500.1 - 1.4 8.4 10.6 1.4 8.3 7.4 1.0 1 0 0 1 1 1 0 Pox virus Ag35 surface protein eIF3_subunit PF08597.5 CDI82500.1 - 1.4 8.4 18.8 1.4 8.3 13.0 1.0 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit Pal1 PF08316.6 CDI82500.1 - 1.6 9.2 12.1 1.8 9.0 8.4 1.0 1 0 0 1 1 1 0 Pal1 cell morphology protein G-alpha PF00503.15 CDI82500.1 - 1.6 7.3 14.9 1.5 7.4 10.3 1.0 1 0 0 1 1 1 0 G-protein alpha subunit DDHD PF02862.12 CDI82500.1 - 1.6 8.4 15.9 1.6 8.4 11.0 1.0 1 0 0 1 1 1 0 DDHD domain DDRGK PF09756.4 CDI82500.1 - 1.7 8.0 24.2 1.7 7.9 16.8 1.0 1 0 0 1 1 1 0 DDRGK domain DUF1644 PF07800.7 CDI82500.1 - 2 8.2 11.6 2.3 8.0 8.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1644) NARP1 PF12569.3 CDI82500.1 - 2.5 6.7 20.3 2.5 6.7 14.1 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 GAGA_bind PF06217.7 CDI82500.1 - 2.5 7.9 16.3 2.5 7.9 11.3 1.0 1 0 0 1 1 1 0 GAGA binding protein-like family FYDLN_acid PF09538.5 CDI82500.1 - 2.6 8.6 12.7 2.9 8.5 8.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) AIF_C PF14721.1 CDI82500.1 - 2.7 8.2 15.5 2.9 8.1 10.7 1.1 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Dala_Dala_lig_N PF01820.16 CDI82500.1 - 2.8 8.2 11.0 3 8.1 7.6 1.1 1 0 0 1 1 1 0 D-ala D-ala ligase N-terminus Pex14_N PF04695.8 CDI82500.1 - 3.5 7.6 27.1 4 7.4 18.8 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Peptidase_S49_N PF08496.5 CDI82500.1 - 3.9 7.2 16.6 4.1 7.1 11.5 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Rtf2 PF04641.7 CDI82500.1 - 4 6.5 16.2 4.1 6.5 11.3 1.0 1 0 0 1 1 1 0 Rtf2 RING-finger ATAD4 PF15321.1 CDI82500.1 - 5 8.2 16.0 6.1 7.9 11.1 1.3 1 0 0 1 1 1 0 ATPase family AAA domain containing 4 Glyco_transf_15 PF01793.11 CDI82500.1 - 5.2 5.9 16.8 5.2 5.9 11.7 1.0 1 0 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase Folate_carrier PF01770.13 CDI82500.1 - 5.5 5.4 12.1 4.9 5.5 8.4 1.0 1 0 0 1 1 1 0 Reduced folate carrier Maf1 PF09174.5 CDI82500.1 - 5.5 6.7 11.0 5.4 6.8 7.6 1.0 1 0 0 1 1 1 0 Maf1 regulator SpoIIP PF07454.6 CDI82500.1 - 5.6 6.0 14.8 5.6 6.0 10.3 1.0 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) GOLD_2 PF13897.1 CDI82500.1 - 6 7.1 8.5 6.1 7.0 5.9 1.1 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking BRF1 PF07741.8 CDI82500.1 - 6 7.1 17.3 8.5 6.6 12.0 1.4 1 0 0 1 1 1 0 Brf1-like TBP-binding domain Corona_nucleoca PF00937.13 CDI82500.1 - 6.4 5.6 21.1 7.1 5.4 14.6 1.0 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein Gti1_Pac2 PF09729.4 CDI82500.1 - 7.2 6.4 14.6 7.3 6.4 10.1 1.0 1 0 0 1 1 1 0 Gti1/Pac2 family Baculo_PP31 PF05311.6 CDI82500.1 - 7.6 5.7 21.3 8.3 5.5 14.8 1.0 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) DUF3464 PF11947.3 CDI82500.1 - 7.7 5.9 15.7 8.1 5.8 10.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) DUF1764 PF08576.5 CDI82500.1 - 7.9 7.3 20.9 9.1 7.1 14.5 1.1 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) ARF7EP_C PF14949.1 CDI82500.1 - 8 6.9 16.2 9.1 6.7 11.2 1.1 1 0 0 1 1 1 0 ARF7 effector protein C-terminus FAM60A PF15396.1 CDI82500.1 - 8.1 6.1 14.2 8.4 6.0 9.8 1.0 1 0 0 1 1 1 0 Protein Family FAM60A YHYH PF14240.1 CDI82500.1 - 8.5 6.0 9.7 10 5.7 6.7 1.1 1 0 0 1 1 1 0 YHYH protein SeqA PF03925.8 CDI82500.1 - 9 5.9 18.7 9.7 5.8 13.0 1.0 1 0 0 1 1 1 0 SeqA protein CPSF100_C PF13299.1 CDI82500.1 - 9.1 6.4 15.7 9.1 6.4 10.9 1.1 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal SR-25 PF10500.4 CDI82503.1 - 0.00013 21.5 11.8 0.00013 21.5 8.2 2.0 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein DUF1510 PF07423.6 CDI82503.1 - 0.0056 16.0 26.4 0.16 11.3 9.6 2.0 2 0 0 2 2 2 2 Protein of unknown function (DUF1510) Peroxin-13_N PF04088.8 CDI82503.1 - 0.0075 16.2 19.0 0.031 14.2 2.6 2.1 2 0 0 2 2 2 2 Peroxin 13, N-terminal region FimP PF09766.4 CDI82503.1 - 0.017 14.1 48.5 0.098 11.7 17.0 2.1 2 0 0 2 2 2 0 Fms-interacting protein YqfQ PF14181.1 CDI82503.1 - 0.026 14.5 30.8 0.19 11.7 11.7 2.0 2 0 0 2 2 2 0 YqfQ-like protein SAPS PF04499.10 CDI82503.1 - 0.034 12.7 18.7 0.041 12.5 13.0 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein IncA PF04156.9 CDI82503.1 - 0.09 12.3 43.4 0.37 10.3 14.9 2.1 2 0 0 2 2 2 0 IncA protein Serinc PF03348.10 CDI82503.1 - 0.11 11.1 26.6 0.081 11.6 8.7 2.0 2 0 0 2 2 2 0 Serine incorporator (Serinc) DUF3449 PF11931.3 CDI82503.1 - 0.16 11.4 24.8 0.13 11.8 7.8 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3449) Trp_oprn_chp PF09534.5 CDI82503.1 - 0.27 10.8 5.9 0.85 9.2 4.1 1.7 1 1 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) FAM176 PF14851.1 CDI82503.1 - 0.28 10.8 16.3 1.5 8.5 0.8 2.1 2 0 0 2 2 2 0 FAM176 family Peptidase_S49_N PF08496.5 CDI82503.1 - 0.6 9.8 28.2 1.9 8.2 4.8 2.1 2 0 0 2 2 2 0 Peptidase family S49 N-terminal DUF4512 PF14975.1 CDI82503.1 - 0.9 10.4 14.1 6.5 7.6 4.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4512) PH_4 PF15404.1 CDI82503.1 - 1.1 8.8 24.9 1.2 8.6 7.1 2.3 2 0 0 2 2 2 0 Pleckstrin homology domain FPN1 PF06963.7 CDI82503.1 - 1.2 7.4 14.9 0.36 9.1 0.9 2.1 2 0 0 2 2 2 0 Ferroportin1 (FPN1) TAP42 PF04177.7 CDI82503.1 - 1.3 7.9 34.0 0.21 10.4 7.7 2.0 2 0 0 2 2 2 0 TAP42-like family DUF3408 PF11888.3 CDI82503.1 - 1.3 8.9 23.7 1.7 8.5 1.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3408) AUX_IAA PF02309.11 CDI82503.1 - 1.3 8.6 25.4 2.8 7.6 9.8 2.0 2 0 0 2 2 2 0 AUX/IAA family SelP_N PF04592.9 CDI82503.1 - 1.4 8.2 24.9 0.21 10.9 5.4 2.0 2 0 0 2 2 2 0 Selenoprotein P, N terminal region Rrp15p PF07890.7 CDI82503.1 - 1.6 8.8 28.1 0.34 10.9 7.9 2.2 2 0 0 2 2 2 0 Rrp15p Ctr PF04145.10 CDI82503.1 - 2.2 8.3 23.7 0.17 11.9 1.6 2.1 1 1 1 2 2 2 0 Ctr copper transporter family Folate_carrier PF01770.13 CDI82503.1 - 2.2 6.6 21.1 2.2 6.6 5.6 2.0 2 0 0 2 2 2 0 Reduced folate carrier Gti1_Pac2 PF09729.4 CDI82503.1 - 2.6 7.8 21.6 2.1 8.2 1.9 2.1 2 0 0 2 2 2 0 Gti1/Pac2 family AIF_C PF14721.1 CDI82503.1 - 2.7 8.2 26.0 1 9.5 7.9 2.1 2 0 0 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term D123 PF07065.9 CDI82503.1 - 2.9 6.8 16.3 2 7.3 1.1 2.0 2 0 0 2 2 2 0 D123 HA2 PF04408.18 CDI82503.1 - 3 7.9 11.5 4.9 7.2 2.3 2.3 2 0 0 2 2 2 0 Helicase associated domain (HA2) DUF2235 PF09994.4 CDI82503.1 - 3.1 7.0 11.4 1.3 8.2 0.8 2.0 2 0 0 2 2 2 0 Uncharacterized alpha/beta hydrolase domain (DUF2235) DUF4557 PF15101.1 CDI82503.1 - 3.1 7.5 53.6 0.33 10.7 17.5 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4557) XAP5 PF04921.9 CDI82503.1 - 3.4 7.1 18.1 1.2 8.6 4.3 2.1 2 0 0 2 2 2 0 XAP5, circadian clock regulator CRF1 PF10380.4 CDI82503.1 - 3.9 7.8 22.2 2.4 8.5 6.1 2.2 2 0 0 2 2 2 0 Transcription factor CRF1 PAT1 PF09770.4 CDI82503.1 - 4.3 5.4 76.0 4.9 5.2 52.7 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 RIC3 PF15361.1 CDI82503.1 - 4.4 7.5 28.8 1.5 9.0 8.4 2.1 2 0 0 2 2 2 0 Resistance to inhibitors of cholinesterase homologue 3 FLO_LFY PF01698.11 CDI82503.1 - 4.7 5.9 28.0 1.5 7.5 9.7 2.0 2 0 0 2 2 2 0 Floricaula / Leafy protein DUF3260 PF11658.3 CDI82503.1 - 4.7 5.2 28.3 2.2 6.3 5.7 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3260) AFT PF08731.6 CDI82503.1 - 4.8 7.4 18.6 0.27 11.4 3.5 2.1 2 0 0 2 2 2 0 Transcription factor AFT DUF1764 PF08576.5 CDI82503.1 - 5.5 7.8 37.4 4.5 8.1 13.9 2.1 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF1764) Herpes_UL87 PF03043.9 CDI82503.1 - 6.3 5.0 18.4 6.6 4.9 12.8 1.1 1 0 0 1 1 1 0 Herpesvirus UL87 family SspB PF04386.8 CDI82503.1 - 6.6 6.3 19.3 2.3 7.8 5.4 2.1 2 0 0 2 2 2 0 Stringent starvation protein B Gastrin PF00918.12 CDI82503.1 - 7.1 7.4 36.6 0.55 11.0 11.6 2.1 2 0 0 2 2 2 0 Gastrin/cholecystokinin family OSTbeta PF15048.1 CDI82503.1 - 7.2 6.7 21.1 0.73 9.9 2.8 2.2 2 0 0 2 2 2 0 Organic solute transporter subunit beta protein BRF1 PF07741.8 CDI82503.1 - 7.8 6.7 30.6 1.1 9.4 8.1 2.3 2 0 0 2 2 2 0 Brf1-like TBP-binding domain Rpp20 PF12328.3 CDI82503.1 - 8.1 6.0 27.8 1.5 8.4 3.9 2.1 2 0 0 2 2 2 0 Rpp20 subunit of nuclear RNase MRP and P TCP PF03634.8 CDI82503.1 - 8.3 6.7 31.4 5 7.4 10.7 2.1 2 0 0 2 2 2 0 TCP family transcription factor Pal1 PF08316.6 CDI82503.1 - 8.6 6.8 20.0 1.1 9.6 5.3 2.1 2 0 0 2 2 2 0 Pal1 cell morphology protein SMN PF06003.7 CDI82503.1 - 8.8 5.3 12.1 0.35 9.9 2.7 1.9 2 0 0 2 2 2 0 Survival motor neuron protein (SMN) DUF2052 PF09747.4 CDI82503.1 - 9.4 6.1 38.3 6.6 6.6 14.3 2.0 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) GAGA_bind PF06217.7 CDI82503.1 - 9.4 6.0 26.9 3.2 7.6 9.3 2.0 2 0 0 2 2 2 0 GAGA binding protein-like family Potyvirid-P3 PF13608.1 CDI82503.1 - 9.4 5.2 27.2 2.4 7.2 4.9 2.0 2 0 0 2 2 2 0 Protein P3 of Potyviral polyprotein EnY2 PF10163.4 CDI82504.1 - 5.2e-05 23.0 0.1 9.1e-05 22.3 0.1 1.3 1 0 0 1 1 1 1 Transcription factor e(y)2 TMEM51 PF15345.1 CDI82508.1 - 0.0031 17.2 11.5 0.0031 17.2 8.0 2.9 2 1 1 3 3 2 1 Transmembrane protein 51 Plasmodium_Vir PF05795.6 CDI82508.1 - 0.0091 15.2 3.4 0.41 9.8 0.0 2.8 1 1 1 2 2 2 1 Plasmodium vivax Vir protein Suf PF05843.9 CDI82508.1 - 0.01 15.6 8.8 0.01 15.6 6.1 3.2 2 1 1 3 3 2 0 Suppressor of forked protein (Suf) Anticodon_1 PF08264.8 CDI82508.1 - 0.014 15.1 0.1 0.039 13.7 0.0 1.8 1 0 0 1 1 1 0 Anticodon-binding domain of tRNA DUF4647 PF15504.1 CDI82508.1 - 0.31 9.8 34.4 0.088 11.6 5.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4647) RAP1 PF07218.6 CDI82508.1 - 0.67 7.9 1.6 0.96 7.4 1.1 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) FLO_LFY PF01698.11 CDI82508.1 - 0.8 8.4 21.3 0.45 9.3 1.7 2.3 2 0 0 2 2 2 0 Floricaula / Leafy protein Draxin PF15550.1 CDI82508.1 - 0.84 9.2 22.4 0.35 10.4 1.5 2.3 2 0 0 2 2 2 0 Draxin MRP-S31 PF15433.1 CDI82508.1 - 2.2 7.6 30.8 0.38 10.1 3.2 2.3 2 0 0 2 2 2 0 Mitochondrial 28S ribosomal protein S31 GAGA_bind PF06217.7 CDI82508.1 - 4 7.3 24.3 1.3 8.8 2.7 2.2 2 0 0 2 2 2 0 GAGA binding protein-like family Herpes_UL87 PF03043.9 CDI82508.1 - 4.2 5.6 21.9 1.5e+02 0.5 9.7 2.0 1 1 1 2 2 2 0 Herpesvirus UL87 family YjgP_YjgQ PF03739.9 CDI82508.1 - 8.4 5.0 16.7 0.13 10.9 1.9 2.2 2 0 0 2 2 2 0 Predicted permease YjgP/YjgQ family CIAPIN1 PF05093.8 CDI82508.1 - 8.4 6.5 21.6 1.2 9.2 1.9 3.3 3 0 0 3 3 3 0 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis CDC37_N PF03234.9 CDI82508.1 - 8.5 6.6 24.1 7 6.9 1.3 2.2 2 0 0 2 2 2 0 Cdc37 N terminal kinase binding Activator_LAG-3 PF11498.3 CDI82510.1 - 0.025 13.3 28.5 0.04 12.6 19.7 1.3 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Suf PF05843.9 CDI82510.1 - 0.041 13.6 3.5 0.044 13.5 2.4 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Med15 PF09606.5 CDI82510.1 - 0.82 7.8 40.9 1 7.4 28.4 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal PAT1 PF09770.4 CDI82510.1 - 2 6.5 21.3 2 6.5 14.8 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TFIIA PF03153.8 CDI82510.1 - 4.4 7.0 18.2 5.5 6.7 12.6 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4175 PF13779.1 CDI82510.1 - 5.4 4.5 27.0 10 3.6 18.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Kelch_2 PF07646.10 CDI82513.1 - 1.2e-05 24.8 0.2 0.0053 16.4 0.0 2.3 1 1 1 2 2 2 2 Kelch motif Kelch_4 PF13418.1 CDI82513.1 - 0.00011 21.9 0.5 0.042 13.6 0.0 2.3 1 1 1 2 2 2 2 Galactose oxidase, central domain Kelch_1 PF01344.20 CDI82513.1 - 0.00024 20.6 0.0 0.0071 15.8 0.0 2.3 2 0 0 2 2 2 1 Kelch motif Kelch_5 PF13854.1 CDI82513.1 - 0.0028 17.5 0.0 0.007 16.2 0.0 1.7 2 0 0 2 2 1 1 Kelch motif Kelch_6 PF13964.1 CDI82513.1 - 0.005 16.9 0.1 0.21 11.8 0.0 2.3 1 1 1 2 2 2 1 Kelch motif PAT1 PF09770.4 CDI82513.1 - 0.01 14.1 37.8 0.012 13.8 26.2 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Kelch_3 PF13415.1 CDI82513.1 - 0.014 15.5 0.0 1.8 8.8 0.0 2.5 2 0 0 2 2 2 0 Galactose oxidase, central domain Asp23 PF03780.8 CDI82513.1 - 0.14 12.4 0.1 0.27 11.5 0.1 1.3 1 0 0 1 1 1 0 Asp23 family Med15 PF09606.5 CDI82513.1 - 0.18 9.9 52.5 0.22 9.6 36.4 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Ndc1_Nup PF09531.5 CDI82513.1 - 0.87 7.9 7.7 1.1 7.6 5.3 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF940 PF06082.6 CDI82513.1 - 1.1 7.6 7.5 1.6 7.1 5.2 1.2 1 0 0 1 1 1 0 Bacterial putative lipoprotein (DUF940) TFIIA PF03153.8 CDI82513.1 - 1.3 8.8 28.8 2.1 8.1 20.0 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit MRP-S31 PF15433.1 CDI82513.1 - 1.7 7.9 12.5 2.6 7.4 8.6 1.3 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 Borrelia_P83 PF05262.6 CDI82513.1 - 4.9 5.3 10.9 6.2 4.9 7.6 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein AvrE PF11725.3 CDI82513.1 - 8.5 3.2 14.2 9.7 3.0 9.9 1.0 1 0 0 1 1 1 0 Pathogenicity factor RAB3GAP2_N PF14655.1 CDI82513.1 - 8.9 5.1 13.1 7.3 5.4 1.2 2.1 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Dynein_heavy PF03028.10 CDI82515.1 - 2.4e-183 611.0 0.0 4.8e-183 609.9 0.0 1.4 1 0 0 1 1 1 1 Dynein heavy chain and region D6 of dynein motor DHC_N2 PF08393.8 CDI82515.1 - 1.6e-111 372.7 5.0 1.6e-111 372.7 3.5 2.5 2 0 0 2 2 2 1 Dynein heavy chain, N-terminal region 2 AAA_6 PF12774.2 CDI82515.1 - 4.8e-75 252.0 0.1 3.2e-73 246.0 0.1 2.5 1 1 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region D1 DHC_N1 PF08385.7 CDI82515.1 - 6.3e-60 203.1 0.0 8.8e-54 182.8 0.0 2.8 1 1 1 2 2 2 2 Dynein heavy chain, N-terminal region 1 MT PF12777.2 CDI82515.1 - 2e-56 191.2 7.1 3.1e-56 190.5 4.9 1.3 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_9 PF12781.2 CDI82515.1 - 2e-49 167.4 1.1 1.5e-48 164.6 0.0 2.6 2 0 0 2 2 2 1 ATP-binding dynein motor region D5 AAA_8 PF12780.2 CDI82515.1 - 1.6e-42 145.3 0.0 4.1e-42 144.0 0.0 1.6 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_7 PF12775.2 CDI82515.1 - 6.7e-39 133.6 0.0 7.5e-20 71.1 0.0 2.5 1 1 1 2 2 2 2 P-loop containing dynein motor region D3 AAA_5 PF07728.9 CDI82515.1 - 2.4e-13 50.0 0.0 0.0025 17.5 0.0 5.7 5 0 0 5 5 5 3 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 CDI82515.1 - 6.6e-05 23.0 1.0 1.1 9.4 0.0 5.3 5 0 0 5 5 5 1 AAA domain AAA PF00004.24 CDI82515.1 - 0.00016 21.8 0.3 1 9.5 0.0 4.2 5 0 0 5 5 4 2 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 CDI82515.1 - 0.013 15.3 0.0 3.6 7.5 0.0 3.8 4 0 0 4 4 3 0 AAA domain AAA_17 PF13207.1 CDI82515.1 - 0.045 14.5 1.7 24 5.7 0.0 4.7 3 0 0 3 3 3 0 AAA domain Miro PF08477.8 CDI82515.1 - 0.094 13.2 0.3 1.2 9.6 0.1 3.0 2 0 0 2 2 2 0 Miro-like protein RNA_helicase PF00910.17 CDI82515.1 - 0.1 12.8 0.1 36 4.5 0.0 3.4 3 0 0 3 3 3 0 RNA helicase AAA_19 PF13245.1 CDI82515.1 - 0.11 12.2 0.2 1.6 8.5 0.1 2.7 2 0 0 2 2 2 0 Part of AAA domain AAA_24 PF13479.1 CDI82515.1 - 0.14 11.6 0.9 22 4.5 0.0 3.1 3 0 0 3 3 2 0 AAA domain Tctex-1 PF03645.8 CDI82518.1 - 2.2e-22 78.7 0.0 2.6e-22 78.5 0.0 1.1 1 0 0 1 1 1 1 Tctex-1 family NHL PF01436.16 CDI82519.1 - 2.9e-13 49.0 1.7 0.00024 20.9 0.0 3.8 3 0 0 3 3 3 3 NHL repeat DUF3328 PF11807.3 CDI82519.1 - 0.0045 16.6 0.0 0.079 12.6 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF3328) 7TMR-DISM_7TM PF07695.6 CDI82519.1 - 3.6 7.2 0.9 6.5 6.3 0.6 1.3 1 0 0 1 1 1 0 7TM diverse intracellular signalling DUF755 PF05501.6 CDI82520.1 - 0.02 14.9 3.1 0.02 14.9 2.1 3.7 2 1 0 2 2 2 0 Domain of unknown function (DUF755) BUD22 PF09073.5 CDI82520.1 - 0.11 11.5 36.8 0.12 11.3 25.5 1.0 1 0 0 1 1 1 0 BUD22 Trypan_PARP PF05887.6 CDI82520.1 - 0.67 9.7 14.3 0.9 9.3 9.9 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) RR_TM4-6 PF06459.7 CDI82520.1 - 2.1 8.1 12.9 2.6 7.8 8.9 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Zip PF02535.17 CDI82525.1 - 0.016 14.2 4.6 0.026 13.5 3.2 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Herpes_UL87 PF03043.9 CDI82525.1 - 0.018 13.4 6.0 0.031 12.6 4.2 1.5 1 1 0 1 1 1 0 Herpesvirus UL87 family Cwf_Cwc_15 PF04889.7 CDI82525.1 - 0.074 12.7 22.4 0.11 12.1 15.5 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein AUX_IAA PF02309.11 CDI82525.1 - 0.14 11.8 13.8 0.27 10.9 9.5 1.4 1 0 0 1 1 1 0 AUX/IAA family Presenilin PF01080.12 CDI82525.1 - 0.26 10.0 12.3 0.41 9.4 8.5 1.2 1 0 0 1 1 1 0 Presenilin Peptidase_S66 PF02016.10 CDI82525.1 - 0.32 9.8 14.2 0.84 8.5 0.6 2.4 1 1 1 2 2 2 0 LD-carboxypeptidase GPCR_chapero_1 PF11904.3 CDI82525.1 - 0.46 9.5 15.0 0.61 9.1 10.4 1.2 1 0 0 1 1 1 0 GPCR-chaperone PLRV_ORF5 PF01690.12 CDI82525.1 - 0.59 9.2 15.9 0.83 8.7 11.0 1.2 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Hid1 PF12722.2 CDI82525.1 - 2.3 5.7 24.1 3.2 5.3 16.7 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Daxx PF03344.10 CDI82525.1 - 2.4 6.5 24.5 4.2 5.7 16.9 1.4 1 0 0 1 1 1 0 Daxx Family DUF3675 PF12428.3 CDI82526.1 - 0.041 14.1 0.5 0.041 14.1 0.3 5.2 3 1 2 5 5 5 0 Protein of unknown function (DUF3675) Trp_oprn_chp PF09534.5 CDI82526.1 - 0.15 11.6 25.8 0.35 10.4 4.4 3.4 2 1 1 3 3 3 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF1510 PF07423.6 CDI82529.1 - 0.00078 18.8 29.0 0.00099 18.5 20.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) CDC45 PF02724.9 CDI82529.1 - 0.004 15.2 21.9 0.0042 15.1 15.2 1.1 1 0 0 1 1 1 1 CDC45-like protein VIT1 PF01988.14 CDI82529.1 - 0.034 13.6 24.4 0.059 12.8 16.9 1.4 1 1 0 1 1 1 0 VIT family Hid1 PF12722.2 CDI82529.1 - 0.04 11.6 29.9 0.043 11.4 20.7 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF4045 PF13254.1 CDI82529.1 - 0.047 12.9 32.4 0.054 12.7 22.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Neur_chan_memb PF02932.11 CDI82529.1 - 0.054 13.3 23.5 0.064 13.1 16.3 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Ni_hydr_CYTB PF01292.15 CDI82529.1 - 0.11 11.9 5.6 8.9 5.6 3.9 2.1 1 1 0 1 1 1 0 Prokaryotic cytochrome b561 Nha1_C PF08619.5 CDI82529.1 - 0.14 11.3 25.9 0.16 11.2 17.9 1.2 1 0 0 1 1 1 0 Alkali metal cation/H+ antiporter Nha1 C terminus Utp14 PF04615.8 CDI82529.1 - 0.19 9.8 37.9 0.2 9.8 26.3 1.0 1 0 0 1 1 1 0 Utp14 protein DUF1183 PF06682.7 CDI82529.1 - 0.2 11.2 18.9 0.24 10.9 13.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) Tetraspannin PF00335.15 CDI82529.1 - 0.25 10.5 8.9 0.37 10.0 6.1 1.4 1 0 0 1 1 1 0 Tetraspanin family PPP4R2 PF09184.6 CDI82529.1 - 0.35 10.3 19.6 0.41 10.1 13.6 1.2 1 0 0 1 1 1 0 PPP4R2 Raftlin PF15250.1 CDI82529.1 - 0.45 8.9 28.1 0.51 8.8 19.5 1.1 1 0 0 1 1 1 0 Raftlin SOBP PF15279.1 CDI82529.1 - 0.47 10.7 32.4 0.55 10.5 22.5 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein SID-1_RNA_chan PF13965.1 CDI82529.1 - 0.51 8.4 18.3 0.62 8.1 12.7 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Ycf1 PF05758.7 CDI82529.1 - 0.52 7.9 26.9 0.54 7.8 18.7 1.0 1 0 0 1 1 1 0 Ycf1 GPCR_chapero_1 PF11904.3 CDI82529.1 - 0.52 9.4 22.4 0.58 9.2 15.6 1.3 1 0 0 1 1 1 0 GPCR-chaperone SAGA-Tad1 PF12767.2 CDI82529.1 - 0.54 9.8 32.7 0.66 9.5 22.7 1.2 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit CRT10 PF08728.5 CDI82529.1 - 0.57 8.1 15.8 0.59 8.0 10.9 1.0 1 0 0 1 1 1 0 CRT10 FA_desaturase PF00487.19 CDI82529.1 - 0.68 9.3 4.1 4 6.7 1.5 2.0 1 1 1 2 2 2 0 Fatty acid desaturase Cytochrom_B_N PF00033.14 CDI82529.1 - 0.75 9.1 6.9 59 2.9 4.8 2.1 1 1 0 1 1 1 0 Cytochrome b(N-terminal)/b6/petB DUF677 PF05055.7 CDI82529.1 - 0.84 8.2 18.9 0.32 9.6 1.5 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF677) BTV_NS2 PF04514.7 CDI82529.1 - 0.84 8.4 21.2 1 8.2 14.7 1.2 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 YndJ PF14158.1 CDI82529.1 - 1 8.4 22.5 1.5 7.7 3.4 2.1 2 0 0 2 2 2 0 YndJ-like protein PLRV_ORF5 PF01690.12 CDI82529.1 - 1 8.4 30.4 1.1 8.3 21.1 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein DUF342 PF03961.8 CDI82529.1 - 1.2 7.5 19.5 1.3 7.3 13.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) U79_P34 PF03064.11 CDI82529.1 - 1.3 8.4 23.2 1.8 8.0 16.1 1.3 1 0 0 1 1 1 0 HSV U79 / HCMV P34 TT_ORF1 PF02956.9 CDI82529.1 - 1.3 7.3 21.0 1.7 7.0 14.6 1.2 1 0 0 1 1 1 0 TT viral orf 1 DUF4220 PF13968.1 CDI82529.1 - 1.8 7.5 14.8 2.3 7.2 10.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4220) BSP_II PF05432.6 CDI82529.1 - 2.1 7.5 13.3 2.6 7.2 9.2 1.1 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) DUF2217 PF10265.4 CDI82529.1 - 2.3 6.8 23.4 2.9 6.5 16.2 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) Dapper PF15268.1 CDI82529.1 - 2.9 6.5 41.2 3 6.5 28.6 1.1 1 0 0 1 1 1 0 Dapper Apt1 PF10351.4 CDI82529.1 - 3.1 6.5 19.6 3.4 6.4 13.6 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF4569 PF15133.1 CDI82529.1 - 3.4 6.9 28.0 3.7 6.8 19.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4569) WTX PF09422.5 CDI82529.1 - 3.9 6.3 24.2 4.8 6.0 16.8 1.1 1 0 0 1 1 1 0 WTX protein SPX PF03105.14 CDI82529.1 - 4.4 7.0 28.2 6.2 6.5 19.5 1.2 1 0 0 1 1 1 0 SPX domain Ndc1_Nup PF09531.5 CDI82529.1 - 4.7 5.5 26.0 5.6 5.2 18.0 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup GAGA_bind PF06217.7 CDI82529.1 - 4.9 7.0 35.4 5.4 6.8 24.5 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family Cellulose_synt PF03552.9 CDI82529.1 - 5.7 5.1 14.8 7.2 4.7 10.3 1.2 1 0 0 1 1 1 0 Cellulose synthase RNA_pol_Rpb1_5 PF04998.12 CDI82529.1 - 6 6.0 18.3 8.4 5.5 12.7 1.3 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 PA26 PF04636.8 CDI82529.1 - 6.6 5.3 21.1 7.3 5.1 14.6 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) APG6 PF04111.7 CDI82529.1 - 6.8 5.6 35.7 8.4 5.3 24.8 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 PCEMA1 PF07418.6 CDI82529.1 - 7.3 5.8 16.6 8.4 5.6 11.5 1.2 1 0 0 1 1 1 0 Acidic phosphoprotein precursor PCEMA1 DUF572 PF04502.8 CDI82529.1 - 7.4 5.6 31.7 8.8 5.4 22.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) FAM60A PF15396.1 CDI82529.1 - 8 6.1 30.5 12 5.5 21.1 1.3 1 0 0 1 1 1 0 Protein Family FAM60A Neur_chan_memb PF02932.11 CDI82530.1 - 0.002 18.0 6.2 0.0025 17.7 4.3 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region TFIIA PF03153.8 CDI82530.1 - 0.0025 17.7 28.4 0.0032 17.4 19.7 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit BAF1_ABF1 PF04684.8 CDI82530.1 - 0.0059 15.5 20.3 0.0059 15.5 14.0 2.9 2 1 0 2 2 1 1 BAF1 / ABF1 chromatin reorganising factor DUF4647 PF15504.1 CDI82530.1 - 0.014 14.3 15.2 0.016 14.0 10.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4647) Ycf1 PF05758.7 CDI82530.1 - 0.014 13.1 12.2 0.017 12.8 8.5 1.0 1 0 0 1 1 1 0 Ycf1 FLO_LFY PF01698.11 CDI82530.1 - 0.056 12.2 7.9 0.092 11.5 5.4 1.5 1 0 0 1 1 1 0 Floricaula / Leafy protein Mem_trans PF03547.13 CDI82530.1 - 0.057 11.7 9.4 0.069 11.4 6.5 1.2 1 0 0 1 1 1 0 Membrane transport protein FHIPEP PF00771.15 CDI82530.1 - 0.068 11.4 3.0 0.084 11.1 2.1 1.2 1 0 0 1 1 1 0 FHIPEP family Peptidase_S64 PF08192.6 CDI82530.1 - 0.072 11.4 17.0 0.093 11.0 11.8 1.3 1 0 0 1 1 1 0 Peptidase family S64 CDC73 PF05179.9 CDI82530.1 - 0.11 11.7 13.5 0.17 11.2 9.4 1.2 1 0 0 1 1 1 0 RNA pol II accessory factor, Cdc73 family SpoVR PF04293.8 CDI82530.1 - 0.13 10.6 8.4 0.17 10.2 5.8 1.1 1 0 0 1 1 1 0 SpoVR like protein CDK5_activator PF03261.10 CDI82530.1 - 0.32 10.2 16.3 0.54 9.5 11.3 1.4 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein Mcm10 PF09332.6 CDI82530.1 - 0.34 10.2 20.1 0.56 9.4 13.9 1.4 1 0 0 1 1 1 0 Mcm10 replication factor Lin-8 PF03353.10 CDI82530.1 - 0.41 9.8 18.8 0.74 9.0 13.0 1.4 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist DUF1510 PF07423.6 CDI82530.1 - 0.44 9.8 32.4 0.17 11.2 16.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) U1snRNP70_N PF12220.3 CDI82530.1 - 0.58 10.5 15.1 0.98 9.7 10.5 1.3 1 0 0 1 1 1 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal DDRGK PF09756.4 CDI82530.1 - 0.93 8.8 22.3 1.2 8.4 15.5 1.1 1 0 0 1 1 1 0 DDRGK domain Utp14 PF04615.8 CDI82530.1 - 1.1 7.3 29.4 1.6 6.7 20.4 1.1 1 0 0 1 1 1 0 Utp14 protein DUF3573 PF12097.3 CDI82530.1 - 1.7 7.1 12.3 2.1 6.8 8.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) GAGA_bind PF06217.7 CDI82530.1 - 1.7 8.4 15.9 2.7 7.8 11.0 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family LCD1 PF09798.4 CDI82530.1 - 1.8 6.4 26.5 2.3 6.0 18.4 1.1 1 0 0 1 1 1 0 DNA damage checkpoint protein Otopetrin PF03189.8 CDI82530.1 - 2.7 6.9 9.1 3.6 6.4 6.3 1.1 1 0 0 1 1 1 0 Otopetrin SID-1_RNA_chan PF13965.1 CDI82530.1 - 3.5 5.6 8.3 4.3 5.3 5.8 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 YfhO PF09586.5 CDI82530.1 - 3.7 5.4 11.4 4.1 5.2 7.9 1.0 1 0 0 1 1 1 0 Bacterial membrane protein YfhO FemAB PF02388.11 CDI82530.1 - 4.4 5.8 16.2 5.9 5.4 11.2 1.1 1 0 0 1 1 1 0 FemAB family Rtf2 PF04641.7 CDI82530.1 - 4.4 6.4 20.5 0.081 12.1 8.9 1.9 2 0 0 2 2 2 0 Rtf2 RING-finger SET PF00856.23 CDI82530.1 - 7.6 6.8 9.3 0.3 11.3 2.1 1.8 2 0 0 2 2 2 0 SET domain MMR1 PF08505.5 CDI82536.1 - 0.053 13.5 23.3 0.06 13.3 16.1 1.0 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein CDC45 PF02724.9 CDI82536.1 - 0.064 11.2 17.1 0.069 11.1 11.9 1.0 1 0 0 1 1 1 0 CDC45-like protein FAM60A PF15396.1 CDI82536.1 - 0.073 12.8 12.4 0.082 12.6 8.6 1.2 1 0 0 1 1 1 0 Protein Family FAM60A MRP-S31 PF15433.1 CDI82536.1 - 0.083 12.3 21.6 0.1 11.9 14.9 1.1 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 Daxx PF03344.10 CDI82536.1 - 0.093 11.2 20.8 0.1 11.0 14.4 1.0 1 0 0 1 1 1 0 Daxx Family TFIIA PF03153.8 CDI82536.1 - 0.23 11.2 37.1 0.26 11.1 25.7 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF1510 PF07423.6 CDI82536.1 - 0.26 10.6 24.7 0.31 10.3 17.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Cyto_heme_lyase PF01265.12 CDI82536.1 - 0.5 9.9 18.0 0.57 9.7 12.5 1.1 1 0 0 1 1 1 0 Cytochrome c/c1 heme lyase SAPS PF04499.10 CDI82536.1 - 0.51 8.9 15.3 0.53 8.8 10.6 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein HemX PF04375.9 CDI82536.1 - 0.52 8.8 29.4 0.53 8.8 20.4 1.0 1 0 0 1 1 1 0 HemX DUF4045 PF13254.1 CDI82536.1 - 0.54 9.4 18.2 0.63 9.2 12.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Ycf1 PF05758.7 CDI82536.1 - 0.56 7.8 21.4 0.67 7.6 14.9 1.0 1 0 0 1 1 1 0 Ycf1 Vfa1 PF08432.5 CDI82536.1 - 0.59 10.1 20.4 0.74 9.8 14.2 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 SPX PF03105.14 CDI82536.1 - 0.64 9.7 17.7 0.87 9.3 12.2 1.3 1 0 0 1 1 1 0 SPX domain Raftlin PF15250.1 CDI82536.1 - 0.72 8.3 17.4 0.83 8.0 12.1 1.1 1 0 0 1 1 1 0 Raftlin PAT1 PF09770.4 CDI82536.1 - 0.75 7.9 48.9 0.84 7.7 33.9 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 AUX_IAA PF02309.11 CDI82536.1 - 0.94 9.1 14.8 1 9.0 10.3 1.1 1 0 0 1 1 1 0 AUX/IAA family CENP-T PF15511.1 CDI82536.1 - 1.1 8.3 23.7 1.3 8.1 16.4 1.0 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Med15 PF09606.5 CDI82536.1 - 1.4 7.0 66.8 1.5 6.9 46.3 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal BORG_CEP PF14957.1 CDI82536.1 - 2 9.3 14.6 3.4 8.6 10.1 1.4 1 0 0 1 1 1 0 Cdc42 effector DUF3332 PF11810.3 CDI82536.1 - 2.1 7.9 7.4 2.6 7.6 5.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3332) GAGA_bind PF06217.7 CDI82536.1 - 2.4 8.0 22.6 2.9 7.7 15.6 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family Neur_chan_memb PF02932.11 CDI82536.1 - 2.8 7.7 16.6 3.2 7.5 11.5 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Hid1 PF12722.2 CDI82536.1 - 2.9 5.4 23.1 3.3 5.2 16.0 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Spore_coat_CotO PF14153.1 CDI82536.1 - 3 7.2 31.4 3.8 6.9 21.8 1.2 1 0 0 1 1 1 0 Spore coat protein CotO DUF2201_N PF13203.1 CDI82536.1 - 3.7 6.6 25.6 4.3 6.4 17.7 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain RR_TM4-6 PF06459.7 CDI82536.1 - 5.5 6.7 23.7 8.1 6.2 16.4 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF3357 PF11837.3 CDI82536.1 - 6.6 6.6 10.5 9.2 6.1 0.2 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3357) Presenilin PF01080.12 CDI82536.1 - 6.8 5.3 12.1 7.5 5.2 8.4 1.1 1 0 0 1 1 1 0 Presenilin Pox_Ag35 PF03286.9 CDI82536.1 - 7.4 6.0 16.9 9.8 5.6 11.7 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DUF4407 PF14362.1 CDI82536.1 - 8.7 5.2 24.0 11 4.8 16.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF4220 PF13968.1 CDI82536.1 - 9.6 5.1 8.4 11 5.0 5.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4220) N6_N4_Mtase PF01555.13 CDI82539.1 - 9 5.7 18.6 1.5e+04 -6.5 12.9 4.0 1 1 0 1 1 1 0 DNA methylase SprA-related PF12118.3 CDI82542.1 - 0.1 11.9 16.1 0.12 11.6 11.2 1.0 1 0 0 1 1 1 0 SprA-related family DUF2217 PF10265.4 CDI82542.1 - 1.2 7.7 14.1 1.5 7.5 9.8 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) HAUS6_N PF14661.1 CDI82542.1 - 1.3 8.3 4.1 1.7 7.9 2.9 1.3 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Prenyltrans_2 PF13249.1 CDI82542.1 - 1.6 9.2 4.2 3.7 7.9 0.0 2.2 1 1 1 2 2 2 0 Prenyltransferase-like Pex14_N PF04695.8 CDI82542.1 - 1.7 8.7 10.3 2.3 8.2 7.1 1.3 1 1 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region OATP PF03137.15 CDI82542.1 - 1.8 6.5 4.4 0.45 8.5 1.0 1.4 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family DUF1005 PF06219.7 CDI82542.1 - 2 6.9 12.5 2.3 6.7 8.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1005) Rifin_STEVOR PF02009.11 CDI82542.1 - 2.7 7.5 7.3 3.7 7.1 5.0 1.2 1 0 0 1 1 1 0 Rifin/stevor family TFIIA PF03153.8 CDI82542.1 - 8.5 6.1 7.7 9.7 5.9 5.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF3446 PF11928.3 CDI82559.1 - 0.59 10.3 17.4 0.13 12.5 8.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3446) CDK2AP PF09806.4 CDI82559.1 - 1.8 8.7 7.8 1.9 8.6 5.0 1.4 1 1 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein Mpp10 PF04006.7 CDI82564.1 - 2.2 6.5 42.3 2.9 6.1 29.3 1.2 1 0 0 1 1 1 0 Mpp10 protein Raftlin PF15250.1 CDI82564.1 - 3.8 5.9 20.8 5.3 5.4 14.4 1.3 1 0 0 1 1 1 0 Raftlin Neur_chan_memb PF02932.11 CDI82564.1 - 6.2 6.6 12.9 7.9 6.2 9.0 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region PA26 PF04636.8 CDI82564.1 - 7.9 5.0 22.0 8.1 5.0 15.3 1.0 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) RNA_pol_Rpb1_1 PF04997.7 CDI82564.1 - 8.1 5.5 14.3 8.7 5.4 9.9 1.0 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 1 Herpes_DNAp_acc PF04929.7 CDI82564.1 - 8.2 5.2 17.1 11 4.8 11.8 1.2 1 0 0 1 1 1 0 Herpes DNA replication accessory factor GAGA_bind PF06217.7 CDI82564.1 - 9 6.1 19.9 11 5.8 13.8 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family G-7-MTase PF12803.2 CDI82564.1 - 9.9 5.1 12.4 13 4.7 8.6 1.2 1 0 0 1 1 1 0 mRNA (guanine-7-)methyltransferase (G-7-MTase) DUF1675 PF07897.6 CDI82565.1 - 1.5 8.6 10.1 1.7 8.4 7.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) DDHD PF02862.12 CDI82565.1 - 2.6 7.7 11.4 2.8 7.6 7.9 1.1 1 0 0 1 1 1 0 DDHD domain Suf PF05843.9 CDI82565.1 - 2.6 7.6 20.9 3.2 7.3 14.5 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Band_3_cyto PF07565.8 CDI82565.1 - 5.1 6.5 12.7 5.4 6.4 8.8 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain SAGA-Tad1 PF12767.2 CDI82565.1 - 6.7 6.3 19.2 7.4 6.1 13.3 1.1 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit Activator_LAG-3 PF11498.3 CDI82565.1 - 6.9 5.2 50.6 8.6 4.9 35.1 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 GYF PF02213.11 CDI82571.1 - 6.3e-16 57.6 0.4 6.3e-16 57.6 0.3 2.3 2 1 0 2 2 2 1 GYF domain RR_TM4-6 PF06459.7 CDI82571.1 - 3.4 7.4 16.5 0.44 10.4 8.0 1.8 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 DUF4613 PF15390.1 CDI82573.1 - 3.5 5.7 25.9 4 5.4 17.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) DUF4657 PF15552.1 CDI82574.1 - 0.074 12.3 2.2 0.13 11.5 1.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4657) Ribosomal_60s PF00428.14 CDI82577.1 - 0.002 18.4 2.6 0.0027 18.0 1.8 1.3 1 0 0 1 1 1 1 60s Acidic ribosomal protein CAF-1_p150 PF11600.3 CDI82577.1 - 0.0045 16.3 16.3 0.0045 16.3 11.3 2.0 2 0 0 2 2 2 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal Shadoo PF14999.1 CDI82577.1 - 0.0061 16.4 2.6 0.01 15.6 1.7 1.5 2 0 0 2 2 2 1 Shadow of prion protein, neuroprotective DUF3915 PF13054.1 CDI82577.1 - 1.4 8.8 6.7 0.46 10.4 0.8 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF3915) ETRAMP PF09716.5 CDI82577.1 - 1.9 8.5 12.2 0.59 10.1 3.9 2.5 2 1 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) DUF4259 PF14078.1 CDI82577.1 - 6.4 7.2 9.5 0.49 10.8 1.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4259) Rxt3 PF08642.5 CDI82577.1 - 8.8 6.6 14.0 2.3 8.5 0.8 2.2 1 1 1 2 2 2 0 Histone deacetylation protein Rxt3 RskA PF10099.4 CDI82578.1 - 0.027 14.1 8.6 0.032 13.9 6.0 1.1 1 0 0 1 1 1 0 Anti-sigma-K factor rskA EcsC PF12787.2 CDI82578.1 - 0.34 10.2 4.7 0.31 10.4 2.7 1.4 1 1 0 1 1 1 0 EcsC protein family Dehalogenase PF13486.1 CDI82578.1 - 1.3 8.4 4.0 1.5 8.2 2.8 1.0 1 0 0 1 1 1 0 Reductive dehalogenase subunit Ribosomal_60s PF00428.14 CDI82578.1 - 2.2 8.7 7.2 0.5 10.7 2.9 1.7 2 0 0 2 2 2 0 60s Acidic ribosomal protein FimP PF09766.4 CDI82579.1 - 5.1e-05 22.5 8.8 6e-05 22.2 6.1 1.0 1 0 0 1 1 1 1 Fms-interacting protein Gastrin PF00918.12 CDI82579.1 - 0.00089 20.0 8.3 0.0012 19.6 5.7 1.1 1 0 0 1 1 1 1 Gastrin/cholecystokinin family Conotoxin PF02950.12 CDI82579.1 - 0.0018 19.0 2.1 0.003 18.3 1.5 1.5 1 0 0 1 1 1 1 Conotoxin DUF2561 PF10812.3 CDI82579.1 - 0.0032 17.0 1.4 0.0033 17.0 1.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2561) ERF PF04404.7 CDI82579.1 - 0.0039 16.7 5.6 0.0046 16.4 3.9 1.2 1 0 0 1 1 1 1 ERF superfamily DUF2782 PF11191.3 CDI82579.1 - 0.0045 16.9 1.7 0.0069 16.3 1.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2782) CCAP PF11105.3 CDI82579.1 - 0.0056 16.4 0.3 0.013 15.1 0.2 1.6 1 1 0 1 1 1 1 Arthropod cardioacceleratory peptide 2a DUF3450 PF11932.3 CDI82579.1 - 0.0059 15.9 9.0 0.0063 15.8 6.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) Spt20 PF12090.3 CDI82579.1 - 0.0067 15.7 1.9 0.0079 15.5 1.3 1.2 1 0 0 1 1 1 1 Spt20 family PSK PF06404.7 CDI82579.1 - 0.0094 16.7 1.1 0.013 16.2 0.7 1.4 1 0 0 1 1 1 1 Phytosulfokine precursor protein (PSK) Suf PF05843.9 CDI82579.1 - 0.0096 15.6 3.6 0.0099 15.6 2.5 1.1 1 0 0 1 1 1 1 Suppressor of forked protein (Suf) DUF3530 PF12048.3 CDI82579.1 - 0.011 14.8 13.5 0.27 10.1 8.4 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3530) DUF3357 PF11837.3 CDI82579.1 - 0.011 15.5 0.1 0.017 14.9 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) Serinc PF03348.10 CDI82579.1 - 0.012 14.3 1.0 0.013 14.2 0.7 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) RskA PF10099.4 CDI82579.1 - 0.013 15.2 5.6 0.019 14.7 3.9 1.2 1 0 0 1 1 1 0 Anti-sigma-K factor rskA IncA PF04156.9 CDI82579.1 - 0.016 14.8 6.1 0.018 14.6 4.2 1.2 1 0 0 1 1 1 0 IncA protein BAF1_ABF1 PF04684.8 CDI82579.1 - 0.017 13.9 8.3 0.017 14.0 5.7 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor EPL1 PF10513.4 CDI82579.1 - 0.02 15.1 3.3 0.024 14.8 2.3 1.1 1 0 0 1 1 1 0 Enhancer of polycomb-like YfhO PF09586.5 CDI82579.1 - 0.026 12.5 0.5 0.031 12.3 0.4 1.0 1 0 0 1 1 1 0 Bacterial membrane protein YfhO TFIIA PF03153.8 CDI82579.1 - 0.028 14.3 8.7 0.027 14.3 6.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF1764 PF08576.5 CDI82579.1 - 0.029 15.1 6.2 0.038 14.7 4.3 1.1 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) FCP1_C PF09309.5 CDI82579.1 - 0.03 13.6 8.1 0.033 13.4 5.6 1.1 1 0 0 1 1 1 0 FCP1, C-terminal DUF2228 PF10228.4 CDI82579.1 - 0.032 13.7 0.8 0.039 13.5 0.5 1.1 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2228) PH_4 PF15404.1 CDI82579.1 - 0.035 13.6 2.5 0.044 13.3 1.7 1.1 1 0 0 1 1 1 0 Pleckstrin homology domain FHIPEP PF00771.15 CDI82579.1 - 0.037 12.3 2.0 0.039 12.2 1.4 1.0 1 0 0 1 1 1 0 FHIPEP family Ctr PF04145.10 CDI82579.1 - 0.038 14.0 0.5 0.041 13.9 0.4 1.1 1 0 0 1 1 1 0 Ctr copper transporter family PepSY_2 PF13670.1 CDI82579.1 - 0.04 13.8 3.3 0.076 12.9 2.3 1.6 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain DUF788 PF05620.6 CDI82579.1 - 0.046 13.5 5.4 0.069 13.0 3.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF788) GBP PF02263.14 CDI82579.1 - 0.047 12.7 1.5 0.35 9.8 0.0 2.0 2 0 0 2 2 2 0 Guanylate-binding protein, N-terminal domain Baculo_PP31 PF05311.6 CDI82579.1 - 0.053 12.7 4.1 0.059 12.6 2.9 1.1 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) Pex16 PF08610.5 CDI82579.1 - 0.069 12.1 1.4 0.077 11.9 0.9 1.2 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) DUF3373 PF11853.3 CDI82579.1 - 0.074 11.5 4.6 0.086 11.3 3.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) MRP-S31 PF15433.1 CDI82579.1 - 0.077 12.3 6.3 0.092 12.1 4.4 1.1 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 FAM176 PF14851.1 CDI82579.1 - 0.083 12.5 0.3 0.093 12.4 0.2 1.1 1 0 0 1 1 1 0 FAM176 family DUF2140 PF09911.4 CDI82579.1 - 0.097 11.8 0.2 0.13 11.4 0.2 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2140) Kei1 PF08552.6 CDI82579.1 - 0.1 12.2 2.3 0.12 12.0 1.6 1.1 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 Pescadillo_N PF06732.6 CDI82579.1 - 0.12 11.6 1.8 0.15 11.2 1.2 1.1 1 0 0 1 1 1 0 Pescadillo N-terminus GRP PF07172.6 CDI82579.1 - 0.15 12.5 0.1 0.23 11.9 0.1 1.3 1 0 0 1 1 1 0 Glycine rich protein family CPSF100_C PF13299.1 CDI82579.1 - 0.17 12.0 3.4 0.2 11.8 2.4 1.1 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal CagX PF03524.10 CDI82579.1 - 0.17 11.1 2.9 0.19 10.9 2.0 1.1 1 0 0 1 1 1 0 Conjugal transfer protein DUF2514 PF10721.4 CDI82579.1 - 0.18 11.5 13.8 0.28 10.8 9.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) Peptidase_U57 PF05582.7 CDI82579.1 - 0.19 10.6 1.8 0.21 10.4 1.2 1.1 1 0 0 1 1 1 0 YabG peptidase U57 Med15 PF09606.5 CDI82579.1 - 0.26 9.4 20.0 0.28 9.3 13.9 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DDHD PF02862.12 CDI82579.1 - 0.37 10.5 3.6 0.46 10.2 2.5 1.1 1 0 0 1 1 1 0 DDHD domain eIF-3_zeta PF05091.7 CDI82579.1 - 0.46 9.0 7.4 0.5 8.9 5.1 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Ribosomal_L18_c PF14204.1 CDI82579.1 - 0.47 11.0 8.4 0.69 10.5 5.8 1.2 1 0 0 1 1 1 0 Ribosomal L18 C-terminal region SHR3_chaperone PF08229.6 CDI82579.1 - 0.48 9.3 6.2 0.64 8.9 4.3 1.2 1 0 0 1 1 1 0 ER membrane protein SH3 WBP-1 PF11669.3 CDI82579.1 - 0.54 10.3 8.1 9.7 6.3 5.6 2.0 1 1 0 1 1 1 0 WW domain-binding protein 1 PAT1 PF09770.4 CDI82579.1 - 0.58 8.3 15.5 0.62 8.2 10.7 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 AIF_C PF14721.1 CDI82579.1 - 0.64 10.2 4.3 0.84 9.8 3.0 1.1 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term DUF4557 PF15101.1 CDI82579.1 - 0.78 9.5 11.2 0.91 9.3 7.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) DUF4175 PF13779.1 CDI82579.1 - 1 6.9 20.1 1.2 6.7 13.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) UPF0560 PF10577.4 CDI82579.1 - 1.2 7.3 8.1 1.3 7.2 5.6 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Trp_oprn_chp PF09534.5 CDI82579.1 - 1.3 8.6 5.9 0.21 11.1 1.9 1.4 2 0 0 2 2 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF3464 PF11947.3 CDI82579.1 - 1.4 8.3 4.8 1.7 8.1 3.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) Glyco_transf_15 PF01793.11 CDI82579.1 - 2 7.2 4.9 2.2 7.1 3.4 1.1 1 0 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase RR_TM4-6 PF06459.7 CDI82579.1 - 3.3 7.5 7.4 3.9 7.2 5.2 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF3260 PF11658.3 CDI82579.1 - 3.6 5.6 7.7 4 5.4 5.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3260) Androgen_recep PF02166.11 CDI82579.1 - 4.4 6.0 13.4 4.5 6.0 6.5 2.1 2 0 0 2 2 2 0 Androgen receptor G0-G1_switch_2 PF15103.1 CDI82579.1 - 5.3 7.3 7.0 8.1 6.7 4.9 1.3 1 0 0 1 1 1 0 G0/G1 switch protein 2 DUF3138 PF11336.3 CDI82579.1 - 8.8 4.3 7.6 11 4.0 5.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Zea_mays_MuDR PF05928.6 CDI82581.1 - 0.0036 16.7 1.9 0.0036 16.7 1.3 3.5 4 0 0 4 4 4 1 Zea mays MURB-like protein (MuDR) Spt20 PF12090.3 CDI82581.1 - 0.081 12.2 13.9 0.051 12.9 1.8 3.1 3 0 0 3 3 3 0 Spt20 family DUF3801 PF12687.2 CDI82581.1 - 0.082 12.4 12.4 0.22 11.0 0.7 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3801) YfhO PF09586.5 CDI82581.1 - 0.59 8.0 0.0 0.59 8.0 0.0 2.4 3 0 0 3 3 3 0 Bacterial membrane protein YfhO Med15 PF09606.5 CDI82581.1 - 8.7 4.4 72.8 0.33 9.0 19.5 3.2 3 0 0 3 3 3 0 ARC105 or Med15 subunit of Mediator complex non-fungal SR-25 PF10500.4 CDI82588.1 - 0.00074 19.0 27.4 0.0019 17.7 8.0 2.2 2 0 0 2 2 2 2 Nuclear RNA-splicing-associated protein DUF1645 PF07816.6 CDI82588.1 - 0.00099 19.6 3.6 0.00099 19.6 2.5 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1645) Cwf_Cwc_15 PF04889.7 CDI82588.1 - 0.16 11.6 23.8 0.096 12.3 1.9 2.1 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein TraV PF09676.5 CDI82588.1 - 0.31 11.7 15.1 0.15 12.8 2.9 2.3 2 0 0 2 2 2 0 Type IV conjugative transfer system lipoprotein (TraV) PBP1_TM PF14812.1 CDI82588.1 - 0.74 10.1 6.4 2 8.7 1.6 2.3 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF2052 PF09747.4 CDI82588.1 - 2.9 7.7 32.6 1 9.2 4.2 2.3 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) DUF4192 PF13830.1 CDI82588.1 - 3.1 7.3 13.4 0.29 10.7 0.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4192) Helicase_RecD PF05127.9 CDI82588.1 - 4.1 6.9 12.3 5.7 6.5 0.7 2.4 2 0 0 2 2 2 0 Helicase FAM60A PF15396.1 CDI82588.1 - 4.2 7.0 25.7 1.4 8.5 3.5 2.1 2 0 0 2 2 2 0 Protein Family FAM60A FYDLN_acid PF09538.5 CDI82588.1 - 6.1 7.4 8.9 2.6 8.6 1.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) FAM176 PF14851.1 CDI82588.1 - 7 6.3 14.8 1.4 8.6 3.0 2.2 2 0 0 2 2 2 0 FAM176 family Acetate_kinase PF00871.12 CDI82588.1 - 7.9 4.8 7.0 8.7 4.7 3.5 1.8 1 1 1 2 2 2 0 Acetokinase family Pex16 PF08610.5 CDI82588.1 - 9.9 5.0 27.7 0.71 8.8 3.6 2.2 2 0 0 2 2 2 0 Peroxisomal membrane protein (Pex16) MIP-T3 PF10243.4 CDI82590.1 - 0.0044 15.5 56.0 0.005 15.3 38.8 1.0 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 Med15 PF09606.5 CDI82590.1 - 0.056 11.6 96.9 0.068 11.3 67.2 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Utp14 PF04615.8 CDI82590.1 - 0.35 8.9 54.4 0.4 8.7 37.7 1.0 1 0 0 1 1 1 0 Utp14 protein CAF-1_p150 PF11600.3 CDI82590.1 - 0.37 10.1 50.4 0.47 9.7 35.0 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Ribosomal_60s PF00428.14 CDI82590.1 - 0.39 11.1 18.4 0.39 11.1 6.7 2.5 2 0 0 2 2 2 0 60s Acidic ribosomal protein DUF4045 PF13254.1 CDI82590.1 - 1.7 7.8 40.9 2.4 7.3 28.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) PAT1 PF09770.4 CDI82590.1 - 1.8 6.7 80.2 2 6.5 55.6 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Asp-B-Hydro_N PF05279.6 CDI82590.1 - 2.8 7.7 34.1 3.3 7.4 23.7 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Shadoo PF14999.1 CDI82590.1 - 8 6.3 16.3 0.035 13.9 3.0 2.1 2 0 0 2 2 2 0 Shadow of prion protein, neuroprotective SOBP PF15279.1 CDI82590.1 - 8.1 6.7 40.1 9.2 6.5 27.8 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein PYST-C1 PF09690.5 CDI82590.1 - 9.8 5.8 17.9 13 5.4 12.0 1.7 1 1 0 1 1 1 0 Plasmodium yoelii subtelomeric region (PYST-C1) Tubulin_2 PF13809.1 CDI82601.1 - 0.005 15.8 0.2 0.0054 15.7 0.1 1.2 1 0 0 1 1 1 1 Tubulin like NHase_beta PF02211.10 CDI82601.1 - 0.022 14.4 1.4 0.033 13.9 0.9 1.2 1 0 0 1 1 1 0 Nitrile hydratase beta subunit eIF_4EBP PF05456.6 CDI82601.1 - 1.1 8.9 6.7 0.21 11.3 1.3 1.9 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) APC_CDC26 PF10471.4 CDI82601.1 - 1.5 9.6 31.0 0.057 14.1 11.4 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit 1 DUF2735 PF10931.3 CDI82601.1 - 2.9 8.2 7.1 0.87 9.8 1.8 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2735) Peptidase_S49_N PF08496.5 CDI82601.1 - 9.1 6.0 8.3 1.4 8.6 2.2 1.9 2 0 0 2 2 2 0 Peptidase family S49 N-terminal DUF4355 PF14265.1 CDI82601.1 - 9.9 6.1 16.0 0.23 11.3 5.8 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4355) Med15 PF09606.5 CDI82604.1 - 1.5e-08 33.3 92.6 1.5e-08 33.3 64.2 3.2 2 1 1 3 3 3 1 ARC105 or Med15 subunit of Mediator complex non-fungal zf-C3HC4 PF00097.20 CDI82614.1 - 2.4e-07 30.3 7.7 4.8e-07 29.3 5.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CDI82614.1 - 4e-06 26.7 9.7 8.3e-06 25.7 6.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 CDI82614.1 - 2.4e-05 24.0 10.8 4.6e-05 23.2 7.5 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.1 CDI82614.1 - 3.9e-05 23.3 3.8 9.2e-05 22.1 2.6 1.6 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_5 PF14634.1 CDI82614.1 - 0.0002 20.9 7.6 0.00061 19.4 5.3 1.8 1 1 1 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.1 CDI82614.1 - 0.00027 20.7 9.5 0.00057 19.6 6.6 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.1 CDI82614.1 - 0.00053 19.6 1.4 0.0011 18.6 1.0 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.1 CDI82614.1 - 0.00083 18.9 7.3 0.0016 18.0 5.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Nse PF11789.3 CDI82614.1 - 0.0014 18.1 3.8 0.0032 16.9 2.6 1.6 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit CitT PF12431.3 CDI82614.1 - 0.025 14.6 0.1 0.99 9.5 0.0 2.7 2 0 0 2 2 2 0 Transcriptional regulator EcoR124_C PF12008.3 CDI82614.1 - 0.087 11.9 0.0 0.16 11.1 0.0 1.3 1 0 0 1 1 1 0 Type I restriction and modification enzyme - subunit R C terminal zf-Apc11 PF12861.2 CDI82614.1 - 0.12 12.1 2.9 0.25 11.1 2.0 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-H2C2_2 PF13465.1 CDI82614.1 - 0.71 10.2 7.8 1.2 9.5 0.1 2.5 2 0 0 2 2 2 0 Zinc-finger double domain zf-RING_4 PF14570.1 CDI82614.1 - 0.73 9.4 12.9 4.5 6.9 9.2 2.0 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain EF-hand_like PF09279.6 CDI82614.1 - 3.3 7.8 7.0 0.24 11.4 0.3 2.4 3 0 0 3 3 3 0 Phosphoinositide-specific phospholipase C, efhand-like Dynamitin PF04912.9 CDI82615.1 - 5.6e-15 55.0 0.0 6e-15 54.9 0.0 1.0 1 0 0 1 1 1 1 Dynamitin Nsp1_C PF05064.8 CDI82615.1 - 0.07 12.7 0.2 0.07 12.7 0.2 1.8 2 1 0 2 2 2 0 Nsp1-like C-terminal region Dynamitin PF04912.9 CDI82616.1 - 1.5e-12 47.0 3.3 2.7e-09 36.3 0.4 3.0 3 0 0 3 3 3 3 Dynamitin Actin PF00022.14 CDI82617.1 - 5e-74 249.0 0.0 6.7e-73 245.3 0.0 2.0 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.8 CDI82617.1 - 0.83 8.1 2.4 15 4.0 0.0 2.8 3 0 0 3 3 3 0 MreB/Mbl protein PNP_UDP_1 PF01048.15 CDI82629.1 - 3.1e-29 101.5 0.0 4.5e-29 101.0 0.0 1.2 1 0 0 1 1 1 1 Phosphorylase superfamily WD40 PF00400.27 CDI82631.1 - 0.0023 17.7 0.4 0.54 10.2 0.0 2.6 2 0 0 2 2 2 2 WD domain, G-beta repeat CAF-1_p150 PF11600.3 CDI82634.1 - 0.0016 17.8 15.4 0.0016 17.8 10.7 3.2 2 1 1 3 3 3 2 Chromatin assembly factor 1 complex p150 subunit, N-terminal AAA_23 PF13476.1 CDI82634.1 - 0.65 10.2 32.0 0.52 10.6 3.3 2.3 2 0 0 2 2 2 0 AAA domain SeqA PF03925.8 CDI82636.1 - 0.00014 21.5 18.5 0.0027 17.4 3.1 3.4 3 0 0 3 3 3 2 SeqA protein Spt20 PF12090.3 CDI82636.1 - 0.0015 17.9 18.2 0.09 12.1 0.8 3.3 3 0 0 3 3 3 3 Spt20 family Herpes_env PF01673.13 CDI82636.1 - 0.0035 15.9 5.1 0.0035 15.9 3.5 2.7 2 1 1 3 3 3 2 Herpesvirus putative major envelope glycoprotein DUF3675 PF12428.3 CDI82636.1 - 0.02 15.1 2.3 0.02 15.1 1.6 4.0 2 2 1 4 4 4 0 Protein of unknown function (DUF3675) HNOBA PF07701.9 CDI82636.1 - 0.11 11.6 0.0 0.11 11.6 0.0 2.9 3 0 0 3 3 3 0 Heme NO binding associated MFS_Mycoplasma PF07672.8 CDI82636.1 - 0.45 9.6 7.2 0.14 11.3 0.1 2.7 3 0 0 3 3 3 0 Mycoplasma MFS transporter Gti1_Pac2 PF09729.4 CDI82636.1 - 1.2 9.0 15.3 0.16 11.8 1.2 3.2 2 1 1 3 3 3 0 Gti1/Pac2 family OAD_gamma PF04277.8 CDI82636.1 - 1.5 9.2 0.0 1.5 9.2 0.0 5.1 5 2 1 6 6 4 0 Oxaloacetate decarboxylase, gamma chain DUF912 PF06024.7 CDI82636.1 - 1.9 8.6 17.2 0.34 10.9 0.4 3.8 4 1 0 4 4 4 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Activator_LAG-3 PF11498.3 CDI82636.1 - 4.1 6.0 61.4 0.43 9.2 3.3 3.2 3 0 0 3 3 3 0 Transcriptional activator LAG-3 PAT1 PF09770.4 CDI82636.1 - 4.7 5.3 46.4 1.1 7.4 21.3 2.1 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 Neur_chan_memb PF02932.11 CDI82636.1 - 5.8 6.7 13.7 3.9e+02 0.7 9.5 2.7 1 1 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region CIAPIN1 PF05093.8 CDI82636.1 - 7.8 6.6 19.7 1.1 9.3 2.1 3.6 3 0 0 3 3 3 0 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis Hom_end_hint PF05203.11 CDI82636.1 - 9.8 5.8 8.7 4.9 6.8 0.6 2.5 2 0 0 2 2 2 0 Hom_end-associated Hint YjgP_YjgQ PF03739.9 CDI82637.1 - 0.55 8.9 13.8 0.073 11.7 6.5 1.8 2 0 0 2 2 2 0 Predicted permease YjgP/YjgQ family DUF3357 PF11837.3 CDI82648.1 - 0.12 12.2 0.0 0.25 11.1 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) DUF1948 PF09185.5 CDI82651.1 - 0.027 14.1 1.3 0.039 13.5 0.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1948) Ribosomal_60s PF00428.14 CDI82651.1 - 0.2 12.1 18.0 0.62 10.5 0.9 2.4 2 0 0 2 2 2 0 60s Acidic ribosomal protein Chorion_2 PF03964.10 CDI82651.1 - 0.22 12.0 12.9 3.2 8.3 0.2 2.2 2 0 0 2 2 2 0 Chorion family 2 APC_CDC26 PF10471.4 CDI82651.1 - 0.49 11.1 11.5 0.19 12.4 6.0 1.8 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit 1 Polyoma_coat2 PF00761.15 CDI82651.1 - 3.3 7.1 14.6 0.22 10.9 5.3 1.9 2 0 0 2 2 2 0 Polyomavirus coat protein Macoilin PF09726.4 CDI82651.1 - 5.3 5.1 8.9 8.1 4.5 6.1 1.2 1 0 0 1 1 1 0 Transmembrane protein BcsB PF03170.8 CDI82651.1 - 6.3 4.6 11.8 0.15 10.0 2.9 1.8 1 1 1 2 2 2 0 Bacterial cellulose synthase subunit DUF1183 PF06682.7 CDI82652.1 - 0.0012 18.4 0.3 0.0015 18.2 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1183) DUF3357 PF11837.3 CDI82652.1 - 0.0044 16.8 1.8 0.0052 16.6 1.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3357) TMEM51 PF15345.1 CDI82652.1 - 0.0083 15.8 4.7 0.0091 15.7 3.3 1.0 1 0 0 1 1 1 1 Transmembrane protein 51 CopD PF05425.8 CDI82652.1 - 0.0084 16.3 0.0 0.0084 16.3 0.0 1.1 1 0 0 1 1 1 1 Copper resistance protein D BatD PF13584.1 CDI82652.1 - 0.015 13.8 0.1 0.017 13.7 0.1 1.0 1 0 0 1 1 1 0 Oxygen tolerance TMEM154 PF15102.1 CDI82652.1 - 0.023 14.4 1.0 0.027 14.1 0.7 1.2 1 0 0 1 1 1 0 TMEM154 protein family DUF2615 PF11027.3 CDI82652.1 - 0.025 14.5 0.4 0.029 14.2 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2615) Zn_peptidase PF04228.8 CDI82652.1 - 0.034 13.3 0.2 0.035 13.3 0.2 1.0 1 0 0 1 1 1 0 Putative neutral zinc metallopeptidase SecY PF00344.15 CDI82652.1 - 0.042 12.7 0.4 0.042 12.7 0.2 1.0 1 0 0 1 1 1 0 SecY translocase Baculo_11_kDa PF06143.6 CDI82652.1 - 0.043 13.1 2.8 0.063 12.6 1.9 1.3 1 0 0 1 1 1 0 Baculovirus 11 kDa family Baculo_E56 PF04639.7 CDI82652.1 - 0.048 12.3 0.6 0.056 12.0 0.4 1.1 1 0 0 1 1 1 0 Baculoviral E56 protein, specific to ODV envelope Herpes_gE PF02480.11 CDI82652.1 - 0.059 11.6 0.0 0.065 11.4 0.0 1.0 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Cortexin PF11057.3 CDI82652.1 - 0.06 12.9 1.1 0.074 12.6 0.7 1.2 1 0 0 1 1 1 0 Cortexin of kidney 7tm_1 PF00001.16 CDI82652.1 - 0.069 12.2 0.4 0.073 12.1 0.3 1.1 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) Plant_vir_prot PF01307.12 CDI82652.1 - 0.092 12.4 0.4 0.1 12.3 0.3 1.2 1 0 0 1 1 1 0 Plant viral movement protein DUF3675 PF12428.3 CDI82652.1 - 0.098 12.9 2.8 0.13 12.4 1.8 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3675) OSTbeta PF15048.1 CDI82652.1 - 0.11 12.6 0.3 0.13 12.2 0.2 1.2 1 0 0 1 1 1 0 Organic solute transporter subunit beta protein Sex_peptide PF08138.6 CDI82652.1 - 0.11 12.3 1.2 0.15 11.9 0.8 1.3 1 0 0 1 1 1 0 Sex peptide (SP) family TMEM52 PF14979.1 CDI82652.1 - 0.11 12.3 0.1 0.12 12.2 0.1 1.1 1 0 0 1 1 1 0 Transmembrane 52 UPF0542 PF15086.1 CDI82652.1 - 0.12 12.1 0.2 0.14 11.9 0.1 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0542 GspL_C PF12693.2 CDI82652.1 - 0.12 12.1 9.4 0.13 11.9 6.5 1.1 1 0 0 1 1 1 0 GspL periplasmic domain Rhabdo_glycop PF00974.13 CDI82652.1 - 0.12 10.5 0.4 0.13 10.5 0.3 1.0 1 0 0 1 1 1 0 Rhabdovirus spike glycoprotein DUF912 PF06024.7 CDI82652.1 - 0.13 12.2 1.6 0.24 11.4 1.1 1.5 1 1 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) MotB_plug PF13677.1 CDI82652.1 - 0.15 11.3 0.5 0.22 10.8 0.3 1.4 1 0 0 1 1 1 0 Membrane MotB of proton-channel complex MotA/MotB EphA2_TM PF14575.1 CDI82652.1 - 0.2 12.0 2.3 0.29 11.5 0.4 1.8 1 1 1 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain CcmD PF04995.9 CDI82652.1 - 0.27 10.9 3.9 0.42 10.3 2.7 1.4 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) PIRT PF15099.1 CDI82652.1 - 0.46 9.7 9.4 0.27 10.4 5.0 1.6 1 1 1 2 2 2 0 Phosphoinositide-interacting protein family Ly49 PF08391.5 CDI82652.1 - 0.52 10.4 3.1 0.67 10.1 2.2 1.2 1 0 0 1 1 1 0 Ly49-like protein, N-terminal region YajC PF02699.10 CDI82652.1 - 1.4 8.6 6.5 1.8 8.2 4.5 1.2 1 0 0 1 1 1 0 Preprotein translocase subunit EspB PF05802.6 CDI82652.1 - 2.3 7.1 9.3 2.5 6.9 6.5 1.0 1 0 0 1 1 1 0 Enterobacterial EspB protein DUF2973 PF11189.3 CDI82652.1 - 3.9 7.3 5.4 1.4 8.7 0.9 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2973) HBS1_N PF08938.5 CDI82654.1 - 4.2 7.5 5.8 1.2 9.3 0.6 2.3 3 0 0 3 3 3 0 HBS1 N-terminus Blt1 PF12754.2 CDI82654.1 - 4.3 6.8 9.6 0.39 10.2 2.9 1.9 1 1 1 2 2 2 0 Cell-cycle control medial ring component AP2 PF00847.15 CDI82661.1 - 1.7e-05 24.9 1.1 4.7e-05 23.4 0.7 1.8 1 0 0 1 1 1 1 AP2 domain Peptidase_S8 PF00082.17 CDI82662.1 - 3.8e-26 91.8 0.2 1e-19 70.7 0.0 2.2 1 1 1 2 2 2 2 Subtilase family PRMT5 PF05185.11 CDI82663.1 - 1.7e-06 27.2 0.0 2.5e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase PrmA PF06325.8 CDI82663.1 - 0.014 14.5 0.0 0.13 11.3 0.0 2.0 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_3 PF01596.12 CDI82663.1 - 0.016 14.3 0.0 0.028 13.4 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase Methyltransf_18 PF12847.2 CDI82663.1 - 0.024 15.2 0.0 0.047 14.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain CMAS PF02353.15 CDI82663.1 - 0.13 11.2 0.0 0.21 10.6 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Serpin PF00079.15 CDI82664.1 - 8.7e-79 265.3 0.2 1e-78 265.0 0.1 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) SR-25 PF10500.4 CDI82665.1 - 0.00042 19.8 12.3 0.00042 19.8 8.5 3.3 2 1 0 2 2 2 1 Nuclear RNA-splicing-associated protein BNIP3 PF06553.7 CDI82665.1 - 0.0032 16.8 6.1 0.0032 16.8 4.2 3.5 2 1 0 2 2 2 1 BNIP3 DUF3337 PF11816.3 CDI82665.1 - 0.17 11.2 20.0 0.57 9.5 1.7 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3337) Band_3_cyto PF07565.8 CDI82665.1 - 2.3 7.6 22.4 1.1 8.7 0.9 2.4 2 0 0 2 2 2 0 Band 3 cytoplasmic domain DUF2052 PF09747.4 CDI82665.1 - 2.3 8.1 32.5 5.4 6.8 5.0 2.4 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) DDHD PF02862.12 CDI82665.1 - 2.8 7.6 26.5 0.17 11.6 2.3 2.5 2 0 0 2 2 2 0 DDHD domain eIF-3_zeta PF05091.7 CDI82665.1 - 3.4 6.1 26.2 6.6 5.2 0.3 3.0 3 0 0 3 3 3 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Raftlin PF15250.1 CDI82665.1 - 5.1 5.5 26.9 1.9 6.9 9.1 2.2 2 0 0 2 2 2 0 Raftlin IncA PF04156.9 CDI82668.1 - 3 7.4 12.9 3.3 7.2 9.0 1.1 1 0 0 1 1 1 0 IncA protein Bac_export_2 PF01312.14 CDI82668.1 - 4.9 5.9 12.9 5.1 5.8 8.9 1.0 1 0 0 1 1 1 0 FlhB HrpN YscU SpaS Family UPF0104 PF03706.8 CDI82668.1 - 5 6.3 13.2 5.2 6.2 9.1 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0104) FA_hydroxylase PF04116.8 CDI82668.1 - 6.8 7.1 7.1 7.2 7.0 4.9 1.2 1 0 0 1 1 1 0 Fatty acid hydroxylase superfamily Neur_chan_memb PF02932.11 CDI82668.1 - 6.9 6.4 10.0 7.3 6.4 6.9 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Chorismate_synt PF01264.16 CDI82670.1 - 0.021 13.3 2.7 0.023 13.1 1.9 1.1 1 0 0 1 1 1 0 Chorismate synthase Chorion_2 PF03964.10 CDI82670.1 - 0.14 12.7 6.8 0.16 12.5 4.7 1.1 1 0 0 1 1 1 0 Chorion family 2 DUF3520 PF12034.3 CDI82670.1 - 1.4 8.9 12.0 1.4 8.9 8.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3520) Ribosomal_60s PF00428.14 CDI82670.1 - 4.2 7.8 6.9 6.4 7.2 4.8 1.5 1 1 0 1 1 1 0 60s Acidic ribosomal protein IF-2B PF01008.12 CDI82670.1 - 4.6 6.1 8.7 4.8 6.0 6.1 1.0 1 0 0 1 1 1 0 Initiation factor 2 subunit family CAF-1_p150 PF11600.3 CDI82673.1 - 0.055 12.8 55.6 0.073 12.4 38.5 1.0 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Hid1 PF12722.2 CDI82673.1 - 0.19 9.3 34.3 0.23 9.1 23.8 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein eIF-3_zeta PF05091.7 CDI82673.1 - 1.2 7.6 33.7 1.4 7.4 23.3 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) BTV_NS2 PF04514.7 CDI82673.1 - 2.3 7.0 26.3 2.8 6.7 18.2 1.3 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Ycf1 PF05758.7 CDI82673.1 - 2.5 5.6 33.9 3.1 5.3 23.5 1.1 1 0 0 1 1 1 0 Ycf1 TOM13 PF08219.6 CDI82675.1 - 0.0068 16.1 0.2 0.0068 16.1 0.1 2.6 1 1 1 2 2 2 1 Outer membrane protein TOM13 7tm_1 PF00001.16 CDI82675.1 - 0.17 10.9 9.5 0.22 10.6 6.6 1.2 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) DUF1183 PF06682.7 CDI82675.1 - 0.21 11.1 13.4 0.25 10.9 9.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) DUF4604 PF15377.1 CDI82675.1 - 0.22 11.7 21.3 0.28 11.3 14.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) SID-1_RNA_chan PF13965.1 CDI82675.1 - 2.3 6.3 14.6 2.4 6.2 10.1 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Utp14 PF04615.8 CDI82675.1 - 3 5.9 28.6 3.2 5.8 19.9 1.0 1 0 0 1 1 1 0 Utp14 protein CENP-T PF15511.1 CDI82675.1 - 3.1 6.9 17.8 4.2 6.5 12.3 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T NPR3 PF03666.8 CDI82675.1 - 4.7 5.6 22.3 5.1 5.5 15.4 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF3347 PF11827.3 CDI82675.1 - 5.6 6.9 27.4 8.2 6.3 19.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3347) SspB PF04386.8 CDI82675.1 - 8.3 5.9 19.5 0.055 13.0 3.6 2.0 2 0 0 2 2 2 0 Stringent starvation protein B DUF3306 PF11748.3 CDI82675.1 - 9.4 6.9 23.8 8.2 7.1 9.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3306) DUF2722 PF10846.3 CDI82677.1 - 0.0039 16.2 2.4 0.0039 16.2 1.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) OmpH PF03938.9 CDI82677.1 - 0.012 15.6 13.1 0.013 15.4 9.1 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Med15 PF09606.5 CDI82677.1 - 0.015 13.5 14.3 0.013 13.7 9.9 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Pex14_N PF04695.8 CDI82677.1 - 0.016 15.2 1.1 0.018 15.0 0.8 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region NAD_binding_6 PF08030.7 CDI82677.1 - 0.019 14.8 0.1 0.024 14.5 0.1 1.1 1 0 0 1 1 1 0 Ferric reductase NAD binding domain DUF4199 PF13858.1 CDI82677.1 - 0.021 14.7 1.0 0.026 14.4 0.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) Packaging_FI PF14000.1 CDI82677.1 - 0.028 14.6 0.3 0.036 14.2 0.2 1.1 1 0 0 1 1 1 0 DNA packaging protein FI EcsC PF12787.2 CDI82677.1 - 0.035 13.4 1.9 0.04 13.3 1.3 1.1 1 0 0 1 1 1 0 EcsC protein family TetR_C_2 PF08361.6 CDI82677.1 - 0.04 13.8 0.4 0.048 13.5 0.3 1.1 1 0 0 1 1 1 0 MAATS-type transcriptional repressor, C-terminal region DivIC PF04977.10 CDI82677.1 - 0.076 12.5 11.3 0.11 12.0 7.8 1.2 1 0 0 1 1 1 0 Septum formation initiator Prp18 PF02840.10 CDI82677.1 - 0.12 12.1 5.0 0.15 11.8 3.5 1.1 1 0 0 1 1 1 0 Prp18 domain EAP30 PF04157.11 CDI82677.1 - 0.17 11.0 7.4 0.17 10.9 5.1 1.2 1 0 0 1 1 1 0 EAP30/Vps36 family RAB3GAP2_N PF14655.1 CDI82677.1 - 0.2 10.6 5.6 0.21 10.5 3.9 1.1 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus DUF853 PF05872.7 CDI82677.1 - 0.21 9.9 2.7 0.24 9.7 1.9 1.0 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) Phosphoesterase PF04185.9 CDI82677.1 - 0.38 9.8 3.1 0.46 9.6 2.1 1.1 1 0 0 1 1 1 0 Phosphoesterase family DUF3523 PF12037.3 CDI82677.1 - 1 8.2 12.4 1.2 8.0 8.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3523) FimP PF09766.4 CDI82677.1 - 1.2 8.1 12.2 1.5 7.8 8.5 1.1 1 0 0 1 1 1 0 Fms-interacting protein DUF775 PF05603.7 CDI82677.1 - 1.7 8.0 6.4 1.9 7.9 4.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF775) FCP1_C PF09309.5 CDI82677.1 - 2 7.6 7.1 2.4 7.4 4.9 1.1 1 0 0 1 1 1 0 FCP1, C-terminal Suf PF05843.9 CDI82677.1 - 2 8.0 7.2 2.4 7.8 5.0 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF2489 PF10675.4 CDI82677.1 - 2 8.0 11.4 2.5 7.7 7.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2489) DUF4518 PF15008.1 CDI82677.1 - 2.4 7.1 6.1 3.6 6.5 4.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4518) UPF0560 PF10577.4 CDI82677.1 - 2.4 6.2 6.3 2.6 6.2 4.3 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 DUF4230 PF14014.1 CDI82677.1 - 3 7.6 8.8 3.8 7.3 6.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4230) DUF4175 PF13779.1 CDI82677.1 - 3.6 5.1 17.7 4.1 4.9 12.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) DUF4557 PF15101.1 CDI82677.1 - 3.7 7.3 9.5 4.2 7.1 6.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) AMP-binding PF00501.23 CDI82678.1 - 0.098 11.0 5.5 0.11 10.8 3.8 1.0 1 0 0 1 1 1 0 AMP-binding enzyme MMR_HSR1 PF01926.18 CDI82678.1 - 0.12 12.3 1.1 0.14 12.0 0.8 1.2 1 0 0 1 1 1 0 50S ribosome-binding GTPase SAGA-Tad1 PF12767.2 CDI82678.1 - 0.95 9.0 31.4 1 8.9 21.7 1.0 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit CDC73 PF05179.9 CDI82678.1 - 1 8.6 18.6 1.3 8.3 12.9 1.1 1 0 0 1 1 1 0 RNA pol II accessory factor, Cdc73 family eIF3_subunit PF08597.5 CDI82678.1 - 1.6 8.2 23.5 1.9 7.9 16.3 1.3 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit Rtf2 PF04641.7 CDI82678.1 - 4.6 6.3 25.7 4.9 6.2 17.8 1.2 1 0 0 1 1 1 0 Rtf2 RING-finger Totivirus_coat PF05518.6 CDI82678.1 - 8.6 4.0 13.7 9 3.9 9.5 1.0 1 0 0 1 1 1 0 Totivirus coat protein AAA_11 PF13086.1 CDI82678.1 - 9.1 5.7 24.6 12 5.4 17.0 1.1 1 0 0 1 1 1 0 AAA domain SR-25 PF10500.4 CDI82679.1 - 0.00034 20.1 23.7 0.00034 20.1 16.5 2.3 1 1 1 2 2 2 1 Nuclear RNA-splicing-associated protein Med15 PF09606.5 CDI82679.1 - 0.0056 14.9 82.5 0.0078 14.4 57.2 1.2 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal PAT1 PF09770.4 CDI82679.1 - 8.9 4.4 69.5 11 4.1 48.2 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF4551 PF15087.1 CDI82679.1 - 9.3 4.4 20.7 12 4.1 14.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) SprA-related PF12118.3 CDI82680.1 - 0.00042 19.7 24.2 0.00042 19.7 16.8 9.4 5 4 3 8 8 8 2 SprA-related family DUF4207 PF13904.1 CDI82680.1 - 0.0082 15.5 1.4 0.0082 15.5 0.9 10.3 9 2 0 9 9 9 3 Domain of unknown function (DUF4207) TctA PF01970.11 CDI82681.1 - 0.0049 15.3 0.6 0.0055 15.1 0.3 1.3 1 1 0 1 1 1 1 Tripartite tricarboxylate transporter TctA family Ribosomal_60s PF00428.14 CDI82681.1 - 3.1 8.2 17.1 6 7.3 11.8 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein Draxin PF15550.1 CDI82681.1 - 7.8 6.0 21.6 10 5.6 15.0 1.2 1 0 0 1 1 1 0 Draxin DAGK_cat PF00781.19 CDI82682.1 - 0.003 16.9 0.4 0.0045 16.4 0.2 1.4 1 1 0 1 1 1 1 Diacylglycerol kinase catalytic domain DUF3439 PF11921.3 CDI82682.1 - 0.0046 16.7 1.6 0.006 16.3 1.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3439) Med15 PF09606.5 CDI82682.1 - 0.066 11.4 9.9 0.075 11.2 6.8 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Sporozoite_P67 PF05642.6 CDI82682.1 - 0.081 10.7 7.7 0.1 10.4 5.4 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen PAT1 PF09770.4 CDI82682.1 - 0.68 8.0 9.0 0.63 8.2 6.3 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Herpes_TAF50 PF03326.8 CDI82682.1 - 0.82 8.5 10.0 0.86 8.4 6.9 1.1 1 0 0 1 1 1 0 Herpesvirus transcription activation factor (transactivator) TP_methylase PF00590.15 CDI82682.1 - 0.91 9.1 9.4 3.6 7.2 1.1 2.0 1 1 1 2 2 2 0 Tetrapyrrole (Corrin/Porphyrin) Methylases TFIIA PF03153.8 CDI82682.1 - 2.2 8.0 11.5 3 7.6 8.0 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Herpes_UL25 PF01499.11 CDI82682.1 - 3.1 6.0 7.0 4 5.6 4.9 1.2 1 0 0 1 1 1 0 Herpesvirus UL25 family Trypan_PARP PF05887.6 CDI82685.1 - 6.1 6.6 21.3 0.02 14.7 5.0 3.2 2 1 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) Cwf_Cwc_15 PF04889.7 CDI82686.1 - 0.71 9.5 28.4 0.87 9.2 7.3 2.5 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein SR-25 PF10500.4 CDI82688.1 - 0.0074 15.7 2.7 0.0074 15.7 1.9 3.6 3 1 0 3 3 3 1 Nuclear RNA-splicing-associated protein LMBR1 PF04791.11 CDI82688.1 - 1.2 7.6 7.0 0.048 12.2 0.1 2.1 2 1 0 2 2 2 0 LMBR1-like membrane protein Conotoxin PF02950.12 CDI82689.1 - 0.0046 17.7 5.8 0.0046 17.7 4.0 4.9 4 1 0 4 4 3 1 Conotoxin DUF912 PF06024.7 CDI82689.1 - 0.014 15.4 3.8 0.014 15.4 2.6 5.0 3 1 2 5 5 5 0 Nucleopolyhedrovirus protein of unknown function (DUF912) HCO3_cotransp PF00955.16 CDI82689.1 - 0.047 12.3 8.2 0.036 12.7 4.7 1.5 1 1 0 1 1 1 0 HCO3- transporter family DDE_Tnp_1_5 PF13737.1 CDI82689.1 - 0.089 12.9 5.5 0.38 10.9 0.1 2.9 2 1 0 2 2 2 0 Transposase DDE domain DUF3899 PF13038.1 CDI82689.1 - 0.25 11.5 0.2 0.25 11.5 0.1 4.2 3 1 2 5 5 5 0 Domain of unknown function (DUF3899) PAT1 PF09770.4 CDI82689.1 - 0.59 8.3 76.8 1.6 6.8 0.3 2.2 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 ODV-E18 PF10717.4 CDI82689.1 - 0.59 9.6 0.0 0.59 9.6 0.0 3.1 3 1 0 3 3 2 0 Occlusion-derived virus envelope protein ODV-E18 ETRAMP PF09716.5 CDI82689.1 - 2.5 8.1 8.8 3.5e+02 1.2 4.6 3.7 1 1 1 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) Na_trans_assoc PF06512.8 CDI82689.1 - 3.7 7.4 38.3 2.4 8.0 18.6 2.2 2 0 0 2 2 2 0 Sodium ion transport-associated TFIIA PF03153.8 CDI82689.1 - 4 7.2 61.2 6.2 6.6 35.3 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit DUF819 PF05684.7 CDI82689.1 - 6.1 5.5 5.6 0.97 8.1 0.1 2.2 1 1 2 3 3 3 0 Protein of unknown function (DUF819) MIP-T3 PF10243.4 CDI82690.1 - 4e-05 22.2 40.0 4.4e-05 22.1 27.8 1.1 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 DUF1777 PF08648.7 CDI82690.1 - 0.19 11.4 81.5 1.5 8.4 26.9 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1777) MLANA PF14991.1 CDI82692.1 - 0.081 12.9 2.9 0.052 13.5 1.1 1.4 1 1 0 1 1 1 0 Protein melan-A Sporozoite_P67 PF05642.6 CDI82692.1 - 0.084 10.7 0.6 0.091 10.6 0.4 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen APC8 PF04049.8 CDI82692.1 - 0.089 12.5 2.1 0.1 12.3 1.4 1.3 1 1 0 1 1 1 0 Anaphase promoting complex subunit 8 / Cdc23 Med15 PF09606.5 CDI82692.1 - 0.37 8.9 15.8 0.44 8.6 11.0 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal CDK2AP PF09806.4 CDI82692.1 - 0.78 9.9 8.1 1 9.5 5.6 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein DUF4386 PF14329.1 CDI82692.1 - 1.8 7.9 12.5 2.3 7.6 8.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4386) DUF2681 PF10883.3 CDI82692.1 - 7.7 6.8 10.4 0.94 9.7 3.9 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) DUF912 PF06024.7 CDI82694.1 - 0.00011 22.1 4.7 0.00012 22.0 3.3 1.1 1 0 0 1 1 1 1 Nucleopolyhedrovirus protein of unknown function (DUF912) PBP1_TM PF14812.1 CDI82694.1 - 0.0013 18.9 2.2 0.002 18.4 1.6 1.3 1 0 0 1 1 1 1 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF1183 PF06682.7 CDI82694.1 - 0.0016 18.0 2.9 0.0018 17.9 2.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1183) DUF4366 PF14283.1 CDI82694.1 - 0.0024 17.3 2.8 0.0025 17.2 1.9 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4366) Kei1 PF08552.6 CDI82694.1 - 0.0041 16.8 3.9 0.0046 16.6 2.7 1.0 1 0 0 1 1 1 1 Inositolphosphorylceramide synthase subunit Kei1 DUF2956 PF11169.3 CDI82694.1 - 0.0057 16.5 14.8 0.0065 16.4 10.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2956) Consortin_C PF15281.1 CDI82694.1 - 0.0066 15.9 3.0 0.007 15.8 2.1 1.1 1 0 0 1 1 1 1 Consortin C-terminus BatD PF13584.1 CDI82694.1 - 0.0076 14.8 4.4 0.0075 14.9 3.0 1.0 1 0 0 1 1 1 1 Oxygen tolerance Viral_Beta_CD PF04530.7 CDI82694.1 - 0.011 15.9 1.9 0.011 15.8 1.3 1.0 1 0 0 1 1 1 0 Viral Beta C/D like family NPR3 PF03666.8 CDI82694.1 - 0.012 14.1 5.7 0.012 14.1 3.9 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DcuC PF03606.10 CDI82694.1 - 0.016 13.4 2.4 0.018 13.3 1.7 1.0 1 0 0 1 1 1 0 C4-dicarboxylate anaerobic carrier Peroxin-13_N PF04088.8 CDI82694.1 - 0.017 15.0 5.3 0.019 14.9 3.7 1.1 1 0 0 1 1 1 0 Peroxin 13, N-terminal region Peptidase_M56 PF05569.6 CDI82694.1 - 0.018 13.9 1.5 0.018 13.9 1.0 1.0 1 0 0 1 1 1 0 BlaR1 peptidase M56 UPF0233 PF06781.7 CDI82694.1 - 0.028 14.0 0.4 0.039 13.5 0.3 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0233) DUF2208 PF09973.4 CDI82694.1 - 0.03 13.5 0.6 0.031 13.5 0.4 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2208) Pex14_N PF04695.8 CDI82694.1 - 0.04 13.9 17.3 0.04 13.9 12.0 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF3899 PF13038.1 CDI82694.1 - 0.047 13.8 0.9 0.063 13.4 0.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3899) DUF2370 PF10176.4 CDI82694.1 - 0.051 12.9 2.9 0.051 12.9 2.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) FimP PF09766.4 CDI82694.1 - 0.056 12.5 23.4 0.057 12.4 16.2 1.1 1 0 0 1 1 1 0 Fms-interacting protein Spore_coat_CotO PF14153.1 CDI82694.1 - 0.061 12.7 14.5 0.053 12.9 10.1 1.1 1 0 0 1 1 1 0 Spore coat protein CotO Glt_symporter PF03616.9 CDI82694.1 - 0.063 11.7 6.4 0.061 11.7 4.5 1.0 1 0 0 1 1 1 0 Sodium/glutamate symporter DUF4064 PF13273.1 CDI82694.1 - 0.076 13.1 0.9 0.1 12.6 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4064) DUF3464 PF11947.3 CDI82694.1 - 0.094 12.1 5.8 0.085 12.3 4.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) Rtf2 PF04641.7 CDI82694.1 - 0.12 11.4 6.7 0.13 11.4 4.7 1.0 1 0 0 1 1 1 0 Rtf2 RING-finger DUF1632 PF07857.7 CDI82694.1 - 0.13 11.4 0.5 0.14 11.3 0.4 1.0 1 0 0 1 1 1 0 CEO family (DUF1632) EIIBC-GUT_N PF03612.9 CDI82694.1 - 0.13 11.8 8.0 0.14 11.7 5.6 1.1 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus DUF2207 PF09972.4 CDI82694.1 - 0.14 10.6 1.7 0.15 10.6 1.2 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Gti1_Pac2 PF09729.4 CDI82694.1 - 0.14 11.9 4.9 0.13 12.1 3.4 1.1 1 0 0 1 1 1 0 Gti1/Pac2 family OATP PF03137.15 CDI82694.1 - 0.16 10.0 11.6 0.16 9.9 8.1 1.0 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Packaging_FI PF14000.1 CDI82694.1 - 0.16 12.1 3.7 0.17 12.0 2.6 1.1 1 0 0 1 1 1 0 DNA packaging protein FI RIC3 PF15361.1 CDI82694.1 - 0.2 11.8 9.0 0.22 11.7 6.3 1.2 1 0 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 CDC45 PF02724.9 CDI82694.1 - 0.21 9.5 7.1 0.17 9.8 4.9 1.0 1 0 0 1 1 1 0 CDC45-like protein Tmem26 PF09772.4 CDI82694.1 - 0.24 10.5 6.6 0.24 10.5 4.6 1.0 1 0 0 1 1 1 0 Transmembrane protein 26 Zip PF02535.17 CDI82694.1 - 0.25 10.3 1.2 0.26 10.2 0.8 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter DUF3306 PF11748.3 CDI82694.1 - 0.25 11.9 9.5 0.29 11.8 6.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3306) Dala_Dala_lig_N PF01820.16 CDI82694.1 - 0.26 11.6 4.0 0.24 11.6 2.8 1.1 1 0 0 1 1 1 0 D-ala D-ala ligase N-terminus BRF1 PF07741.8 CDI82694.1 - 0.26 11.5 10.2 0.26 11.5 7.1 1.2 1 0 0 1 1 1 0 Brf1-like TBP-binding domain CD20 PF04103.10 CDI82694.1 - 0.31 10.9 7.3 0.35 10.7 5.0 1.0 1 0 0 1 1 1 0 CD20-like family HCO3_cotransp PF00955.16 CDI82694.1 - 0.35 9.4 2.4 0.37 9.4 1.6 1.0 1 0 0 1 1 1 0 HCO3- transporter family DcuA_DcuB PF03605.9 CDI82694.1 - 0.38 9.5 1.7 0.38 9.5 1.2 1.0 1 0 0 1 1 1 0 Anaerobic c4-dicarboxylate membrane transporter RED_N PF07808.8 CDI82694.1 - 0.46 9.6 19.2 0.41 9.8 13.3 1.1 1 0 0 1 1 1 0 RED-like protein N-terminal region Serinc PF03348.10 CDI82694.1 - 0.49 9.0 9.9 0.49 9.0 6.9 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) Scs3p PF10261.4 CDI82694.1 - 0.49 9.3 1.8 0.57 9.1 1.2 1.2 1 0 0 1 1 1 0 Inositol phospholipid synthesis and fat-storage-inducing TM RICTOR_N PF14664.1 CDI82694.1 - 0.5 8.8 6.5 0.5 8.9 4.5 1.0 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR, N-term Band_3_cyto PF07565.8 CDI82694.1 - 0.51 9.7 11.0 0.52 9.7 7.6 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain SpoIIP PF07454.6 CDI82694.1 - 0.53 9.3 7.2 0.47 9.5 5.0 1.0 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) DUF4635 PF15466.1 CDI82694.1 - 0.54 9.5 10.0 0.72 9.1 6.9 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4635) Folate_carrier PF01770.13 CDI82694.1 - 0.55 8.6 8.1 0.56 8.6 5.6 1.0 1 0 0 1 1 1 0 Reduced folate carrier Afi1 PF07792.7 CDI82694.1 - 0.55 10.2 10.5 0.52 10.3 7.3 1.1 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking DUF913 PF06025.7 CDI82694.1 - 0.59 8.8 5.3 0.57 8.8 3.7 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Peptidase_S49_N PF08496.5 CDI82694.1 - 0.64 9.8 10.3 0.72 9.6 7.1 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Rxt3 PF08642.5 CDI82694.1 - 0.65 10.2 6.1 0.7 10.1 4.2 1.1 1 0 0 1 1 1 0 Histone deacetylation protein Rxt3 DUF3619 PF12279.3 CDI82694.1 - 0.75 9.8 8.4 0.74 9.8 5.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3619) TFIIA PF03153.8 CDI82694.1 - 0.86 9.4 22.7 0.76 9.6 15.8 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Ctr PF04145.10 CDI82694.1 - 0.91 9.5 8.0 1 9.4 5.5 1.1 1 0 0 1 1 1 0 Ctr copper transporter family Paramyxo_ncap PF00973.14 CDI82694.1 - 1.1 7.9 5.6 1 8.0 3.9 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Neur_chan_memb PF02932.11 CDI82694.1 - 1.1 9.1 4.2 1 9.2 2.9 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region SeqA PF03925.8 CDI82694.1 - 1.3 8.7 11.0 1.4 8.6 7.6 1.1 1 0 0 1 1 1 0 SeqA protein Bul1_N PF04425.7 CDI82694.1 - 1.3 7.5 7.7 1.1 7.7 5.4 1.0 1 0 0 1 1 1 0 Bul1 N terminus RP-C_C PF11800.3 CDI82694.1 - 1.3 8.6 10.3 1.3 8.6 7.1 1.0 1 0 0 1 1 1 0 Replication protein C C-terminal region Glyco_transf_15 PF01793.11 CDI82694.1 - 1.4 7.7 11.1 1.5 7.6 7.7 1.0 1 0 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase PUCC PF03209.10 CDI82694.1 - 1.4 7.5 4.5 1.6 7.3 3.1 1.0 1 0 0 1 1 1 0 PUCC protein eIF-3_zeta PF05091.7 CDI82694.1 - 1.6 7.2 16.0 1.5 7.3 11.1 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF605 PF04652.11 CDI82694.1 - 2 7.7 17.4 1.8 7.8 12.1 1.0 1 0 0 1 1 1 0 Vta1 like SID-1_RNA_chan PF13965.1 CDI82694.1 - 2.1 6.4 5.1 1.9 6.5 3.5 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DUF2347 PF09804.4 CDI82694.1 - 2.1 7.5 6.3 2.1 7.5 4.4 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2347) DUF4492 PF14899.1 CDI82694.1 - 2.2 7.8 0.0 2.2 7.8 0.0 2.9 1 1 1 2 2 1 0 Domain of unknown function (DUF4492) Spore_YhcN_YlaJ PF09580.5 CDI82694.1 - 2.2 8.3 10.2 2.1 8.4 7.1 1.1 1 0 0 1 1 1 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) Ycf1 PF05758.7 CDI82694.1 - 2.3 5.8 11.3 2 6.0 7.8 1.0 1 0 0 1 1 1 0 Ycf1 CRF1 PF10380.4 CDI82694.1 - 2.4 8.5 8.4 2.2 8.6 5.8 1.1 1 0 0 1 1 1 0 Transcription factor CRF1 Suf PF05843.9 CDI82694.1 - 2.4 7.7 22.2 2.6 7.7 15.4 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF853 PF05872.7 CDI82694.1 - 2.4 6.3 9.3 2.3 6.4 6.4 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) Pex16 PF08610.5 CDI82694.1 - 2.6 6.9 10.9 2.6 6.9 7.5 1.2 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) GOLD_2 PF13897.1 CDI82694.1 - 2.6 8.2 4.3 2.8 8.1 3.0 1.1 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking DUF1266 PF06889.6 CDI82694.1 - 2.8 7.7 8.1 2.6 7.7 5.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1266) ABC2_membrane_3 PF12698.2 CDI82694.1 - 3 6.7 5.0 3.1 6.7 3.4 1.0 1 0 0 1 1 1 0 ABC-2 family transporter protein Herpes_UL4 PF03277.8 CDI82694.1 - 3.2 6.9 8.3 3 7.0 5.8 1.1 1 0 0 1 1 1 0 Herpesvirus UL4 family DUF2126 PF09899.4 CDI82694.1 - 3.4 5.5 9.0 3.3 5.6 6.2 1.0 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) Anoctamin PF04547.7 CDI82694.1 - 3.4 6.2 8.6 3.4 6.1 5.9 1.1 1 0 0 1 1 1 0 Calcium-activated chloride channel Ndc1_Nup PF09531.5 CDI82694.1 - 3.5 5.9 9.4 3.1 6.1 6.5 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Maf1 PF09174.5 CDI82694.1 - 3.5 7.4 6.7 3.6 7.3 4.6 1.1 1 0 0 1 1 1 0 Maf1 regulator DUF2615 PF11027.3 CDI82694.1 - 4.2 7.3 10.6 7.5 6.5 7.3 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2615) SHQ1 PF04925.10 CDI82694.1 - 4.4 6.7 8.8 4.3 6.7 6.1 1.0 1 0 0 1 1 1 0 SHQ1 protein Frizzled PF01534.12 CDI82694.1 - 4.6 5.9 5.1 4.9 5.8 3.6 1.0 1 0 0 1 1 1 0 Frizzled/Smoothened family membrane region DUF3449 PF11931.3 CDI82694.1 - 5 6.5 12.9 5.8 6.3 8.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3449) DUF2828 PF11443.3 CDI82694.1 - 5.2 5.1 8.5 5.3 5.1 5.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) DUF2813 PF11398.3 CDI82694.1 - 5.3 6.0 15.1 5.3 6.0 10.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2813) 7tm_1 PF00001.16 CDI82694.1 - 5.4 6.0 7.4 12 4.9 5.4 1.4 1 1 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) Nucleoside_tran PF01733.13 CDI82694.1 - 5.4 6.0 7.0 5.9 5.9 4.8 1.1 1 0 0 1 1 1 0 Nucleoside transporter DUF4628 PF15429.1 CDI82694.1 - 5.6 6.3 9.6 5.9 6.2 6.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4628) DnaJ-X PF14308.1 CDI82694.1 - 5.6 6.1 12.9 6.6 5.9 9.0 1.1 1 0 0 1 1 1 0 X-domain of DnaJ-containing FAM60A PF15396.1 CDI82694.1 - 6.2 6.5 9.2 6.8 6.3 6.4 1.1 1 0 0 1 1 1 0 Protein Family FAM60A SAGA-Tad1 PF12767.2 CDI82694.1 - 6.2 6.3 17.1 5.9 6.4 11.9 1.1 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit FHIPEP PF00771.15 CDI82694.1 - 6.4 4.9 12.3 6.4 4.9 8.5 1.0 1 0 0 1 1 1 0 FHIPEP family Het-C PF07217.6 CDI82694.1 - 6.4 4.8 8.5 6.4 4.8 5.9 1.1 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C G-alpha PF00503.15 CDI82694.1 - 7.3 5.1 15.1 7.9 5.0 10.5 1.0 1 0 0 1 1 1 0 G-protein alpha subunit Peptidase_S15 PF02129.13 CDI82694.1 - 7.6 5.8 10.8 7.2 5.9 7.5 1.0 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Hid1 PF12722.2 CDI82694.1 - 8.6 3.8 14.1 9 3.8 9.8 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Folliculin PF11704.3 CDI82694.1 - 9.1 5.8 10.0 10 5.6 6.9 1.2 1 0 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport DUF897 PF05982.7 CDI82694.1 - 9.7 4.8 6.5 9.9 4.8 4.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF897) MIP-T3 PF10243.4 CDI82696.1 - 8.9e-06 24.4 49.4 8.9e-06 24.4 34.2 3.9 3 1 0 3 3 3 1 Microtubule-binding protein MIP-T3 PRP38_assoc PF12871.2 CDI82696.1 - 0.0034 17.8 5.9 0.0034 17.8 4.1 7.8 4 2 2 7 7 7 1 Pre-mRNA-splicing factor 38-associated hydrophilic C-term Exosortase_EpsH PF09721.5 CDI82697.1 - 0.0084 15.3 1.0 0.012 14.8 0.7 1.3 1 0 0 1 1 1 1 Transmembrane exosortase (Exosortase_EpsH) Dsh_C PF12316.3 CDI82697.1 - 0.021 14.9 5.1 0.027 14.5 3.6 1.1 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal YjgP_YjgQ PF03739.9 CDI82697.1 - 0.029 13.1 0.5 0.041 12.6 0.3 1.2 1 0 0 1 1 1 0 Predicted permease YjgP/YjgQ family Pol_alpha_B_N PF08418.5 CDI82697.1 - 0.084 12.3 9.9 0.12 11.8 6.9 1.3 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal LMBR1 PF04791.11 CDI82697.1 - 0.14 10.7 7.9 0.17 10.4 5.5 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF2339 PF10101.4 CDI82697.1 - 0.21 9.8 10.8 0.089 11.0 5.7 1.5 1 1 0 1 1 1 0 Predicted membrane protein (DUF2339) DUF4401 PF14351.1 CDI82697.1 - 0.24 10.3 7.0 0.42 9.5 4.8 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4401) DUF1275 PF06912.6 CDI82697.1 - 0.62 9.2 8.1 0.058 12.5 2.7 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1275) TFIIA PF03153.8 CDI82697.1 - 1.1 9.0 33.6 1.2 8.9 23.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Pro_dh-DNA_bdg PF14850.1 CDI82697.1 - 1.6 8.9 6.2 0.27 11.4 0.7 2.1 1 1 1 2 2 2 0 DNA-binding domain of Proline dehydrogenase DUF1183 PF06682.7 CDI82697.1 - 2.1 7.8 18.5 28 4.1 12.8 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1183) CDK5_activator PF03261.10 CDI82697.1 - 2.2 7.5 15.2 2.6 7.3 10.5 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein AAA_24 PF13479.1 CDI82697.1 - 2.4 7.6 7.8 3.1 7.3 5.4 1.1 1 0 0 1 1 1 0 AAA domain DUF4184 PF13803.1 CDI82697.1 - 2.7 7.2 5.9 0.55 9.5 0.9 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4184) AAA_23 PF13476.1 CDI82697.1 - 3.3 7.9 11.4 4 7.7 7.9 1.3 1 0 0 1 1 1 0 AAA domain DUF966 PF06136.8 CDI82697.1 - 3.6 6.9 13.5 4.6 6.5 9.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF966) SecY PF00344.15 CDI82697.1 - 7.1 5.4 7.2 0.54 9.1 1.2 1.7 1 1 1 2 2 2 0 SecY translocase Ycf1 PF05758.7 CDI82697.1 - 8.8 3.9 9.8 10 3.6 6.8 1.1 1 0 0 1 1 1 0 Ycf1 HlyD_2 PF12700.2 CDI82697.1 - 9.1 5.3 12.4 10 5.1 8.6 1.1 1 0 0 1 1 1 0 HlyD family secretion protein Hid1 PF12722.2 CDI82697.1 - 9.5 3.7 15.7 10 3.6 10.9 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein BAF1_ABF1 PF04684.8 CDI82702.1 - 0.0074 15.1 24.1 0.0074 15.1 16.7 7.4 2 1 5 8 8 8 1 BAF1 / ABF1 chromatin reorganising factor FimP PF09766.4 CDI82702.1 - 0.2 10.6 13.0 0.19 10.7 7.8 1.7 2 0 0 2 2 2 0 Fms-interacting protein Spt20 PF12090.3 CDI82702.1 - 1.4 8.2 8.5 0.41 9.9 3.5 1.8 2 0 0 2 2 2 0 Spt20 family eIF-3_zeta PF05091.7 CDI82702.1 - 2.9 6.4 11.5 0.57 8.7 5.5 1.6 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Pex16 PF08610.5 CDI82702.1 - 3 6.7 5.1 5.4 5.9 3.5 1.3 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) DnaJ PF00226.26 CDI82706.1 - 0.0032 17.1 1.2 0.0056 16.3 0.0 2.0 2 0 0 2 2 2 1 DnaJ domain Cellulose_synt PF03552.9 CDI82706.1 - 1 7.5 7.0 0.049 11.9 0.1 1.9 2 0 0 2 2 2 0 Cellulose synthase DUF1510 PF07423.6 CDI82708.1 - 3.1e-06 26.7 5.8 3.4e-06 26.5 4.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) RCR PF12273.3 CDI82708.1 - 0.0005 20.6 17.9 0.00065 20.2 12.4 1.1 1 0 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red DUF3357 PF11837.3 CDI82708.1 - 0.00052 19.8 1.0 0.00052 19.8 0.7 2.3 1 1 1 2 2 2 1 Domain of unknown function (DUF3357) TMEM154 PF15102.1 CDI82708.1 - 0.00095 18.9 4.3 0.00095 18.9 3.0 2.2 1 1 1 2 2 1 1 TMEM154 protein family DUF1183 PF06682.7 CDI82708.1 - 0.005 16.4 3.8 0.006 16.2 2.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1183) SpoIIIAH PF12685.2 CDI82708.1 - 0.0064 16.0 6.6 0.017 14.6 4.6 1.6 1 1 0 1 1 1 1 SpoIIIAH-like protein EphA2_TM PF14575.1 CDI82708.1 - 0.012 15.9 2.8 0.012 15.9 2.0 2.7 1 1 1 2 2 1 0 Ephrin type-A receptor 2 transmembrane domain Cytochrom_B_N PF00033.14 CDI82708.1 - 0.014 14.7 0.6 0.014 14.7 0.4 1.7 1 1 1 2 2 2 0 Cytochrome b(N-terminal)/b6/petB OAD_gamma PF04277.8 CDI82708.1 - 0.035 14.4 0.5 0.14 12.5 0.4 1.9 1 1 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain Fusion_gly_K PF01621.12 CDI82708.1 - 0.043 12.8 2.7 0.05 12.6 1.9 1.0 1 0 0 1 1 1 0 Cell fusion glycoprotein K K_trans PF02705.11 CDI82708.1 - 0.043 12.1 9.2 0.047 12.0 6.4 1.0 1 0 0 1 1 1 0 K+ potassium transporter m04gp34like PF12216.3 CDI82708.1 - 0.048 13.0 2.0 0.048 13.0 1.1 1.2 1 1 0 1 1 1 0 Immune evasion protein Ion_trans PF00520.26 CDI82708.1 - 0.084 12.1 0.0 0.099 11.8 0.0 1.1 1 0 0 1 1 1 0 Ion transport protein YjgP_YjgQ PF03739.9 CDI82708.1 - 0.11 11.2 4.7 0.19 10.4 3.2 1.5 1 1 0 1 1 1 0 Predicted permease YjgP/YjgQ family DUF3592 PF12158.3 CDI82708.1 - 0.16 11.7 0.2 0.2 11.4 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3592) HemY_N PF07219.8 CDI82708.1 - 0.17 11.4 6.8 0.51 9.9 4.5 1.9 1 1 0 1 1 1 0 HemY protein N-terminus SID-1_RNA_chan PF13965.1 CDI82708.1 - 0.17 10.0 11.2 0.18 9.9 7.8 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 NicO PF03824.11 CDI82708.1 - 0.2 10.9 10.2 0.24 10.6 7.1 1.2 1 0 0 1 1 1 0 High-affinity nickel-transport protein CLPTM1 PF05602.7 CDI82708.1 - 0.24 10.0 9.9 0.25 10.0 6.8 1.0 1 0 0 1 1 1 0 Cleft lip and palate transmembrane protein 1 (CLPTM1) Pex16 PF08610.5 CDI82708.1 - 0.27 10.1 13.9 0.32 9.9 9.6 1.1 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) DUF4293 PF14126.1 CDI82708.1 - 0.32 10.9 6.7 0.05 13.5 1.1 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4293) Mem_trans PF03547.13 CDI82708.1 - 0.37 9.0 10.4 0.39 8.9 7.2 1.0 1 0 0 1 1 1 0 Membrane transport protein Neur PF00064.13 CDI82708.1 - 0.45 8.5 5.1 0.51 8.3 3.5 1.2 1 0 0 1 1 1 0 Neuraminidase Herpes_UL87 PF03043.9 CDI82708.1 - 0.61 8.3 12.3 0.66 8.3 8.5 1.0 1 0 0 1 1 1 0 Herpesvirus UL87 family Ycf1 PF05758.7 CDI82708.1 - 0.68 7.5 13.8 0.73 7.4 9.6 1.0 1 0 0 1 1 1 0 Ycf1 DUF3169 PF11368.3 CDI82708.1 - 1.1 8.4 4.3 0.39 9.8 1.4 1.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3169) Ctr PF04145.10 CDI82708.1 - 1.1 9.2 14.2 34 4.4 9.8 2.0 1 1 0 1 1 1 0 Ctr copper transporter family DUF1345 PF07077.6 CDI82708.1 - 1.8 8.0 4.8 1.1 8.7 2.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1345) Peptidase_S49_N PF08496.5 CDI82708.1 - 1.8 8.3 19.9 2.8 7.7 13.8 1.4 1 1 0 1 1 1 0 Peptidase family S49 N-terminal DUF3959 PF13105.1 CDI82708.1 - 1.9 7.7 11.6 2.4 7.4 8.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3959) Tetraspannin PF00335.15 CDI82708.1 - 2.1 7.5 11.0 6.5 5.9 7.6 1.7 1 1 0 1 1 1 0 Tetraspanin family Cytochrom_C_asm PF01578.15 CDI82708.1 - 2.1 7.8 6.6 4.3 6.8 4.6 1.6 1 1 0 1 1 1 0 Cytochrome C assembly protein MAPEG PF01124.13 CDI82708.1 - 2.8 7.5 8.7 7.7 6.1 6.1 1.7 1 1 0 1 1 1 0 MAPEG family PRK PF00485.13 CDI82708.1 - 3 7.3 8.1 3.4 7.1 5.6 1.1 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family Chordopox_G3 PF06129.7 CDI82708.1 - 3.2 7.9 9.1 11 6.2 6.3 1.8 1 1 0 1 1 1 0 Chordopoxvirus G3 protein DUF843 PF05814.6 CDI82708.1 - 3.7 7.3 6.8 0.84 9.4 2.4 1.7 1 1 1 2 2 2 0 Baculovirus protein of unknown function (DUF843) DUF2140 PF09911.4 CDI82708.1 - 3.9 6.6 14.1 0.049 12.8 3.9 1.8 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2140) DUF2782 PF11191.3 CDI82708.1 - 4.7 7.2 10.0 14 5.7 6.9 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2782) FHIPEP PF00771.15 CDI82708.1 - 4.7 5.4 16.4 7.8 4.6 11.2 1.5 1 1 0 1 1 1 0 FHIPEP family FliP PF00813.15 CDI82708.1 - 5.2 6.7 9.6 6.9 6.3 6.7 1.2 1 0 0 1 1 1 0 FliP family PDR_CDR PF06422.7 CDI82708.1 - 5.3 6.7 7.9 1.4e+02 2.2 5.5 2.1 1 1 0 1 1 1 0 CDR ABC transporter DUF4175 PF13779.1 CDI82708.1 - 5.5 4.5 45.1 6.3 4.3 31.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Folate_carrier PF01770.13 CDI82708.1 - 5.6 5.3 16.5 18 3.7 11.4 1.7 1 1 0 1 1 1 0 Reduced folate carrier RskA PF10099.4 CDI82708.1 - 6.8 6.3 10.8 17 5.1 6.6 2.0 1 1 0 1 1 1 0 Anti-sigma-K factor rskA DUF3530 PF12048.3 CDI82708.1 - 6.9 5.5 24.3 19 4.1 16.9 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3530) DUF3260 PF11658.3 CDI82708.1 - 8.4 4.4 16.9 10 4.1 11.5 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3260) Cellulose_synt PF03552.9 CDI82708.1 - 8.5 4.5 6.2 9.3 4.3 4.3 1.3 1 0 0 1 1 1 0 Cellulose synthase TadE PF07811.7 CDI82708.1 - 9.1 6.2 8.8 16 5.4 6.1 1.5 1 0 0 1 1 1 0 TadE-like protein PAT1 PF09770.4 CDI82711.1 - 0.01 14.1 82.6 0.014 13.6 57.3 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Med15 PF09606.5 CDI82711.1 - 4 5.5 120.4 0.0026 16.0 66.6 2.1 1 1 1 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal Pkinase PF00069.20 CDI82712.1 - 1.8e-16 60.0 0.0 1.4e-09 37.4 0.0 2.3 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CDI82712.1 - 1.7e-12 46.9 0.0 2.4e-06 26.8 0.0 2.7 2 1 1 3 3 3 2 Protein tyrosine kinase Kinase-like PF14531.1 CDI82712.1 - 1.4e-06 27.4 0.0 0.01 14.8 0.0 2.2 1 1 1 2 2 2 2 Kinase-like APH PF01636.18 CDI82712.1 - 0.12 12.1 6.8 12 5.5 0.0 4.2 4 1 1 5 5 5 0 Phosphotransferase enzyme family Radical_SAM PF04055.16 CDI82714.1 - 4.1e-10 40.0 0.0 6.7e-08 32.8 0.0 2.9 1 1 0 1 1 1 1 Radical SAM superfamily Fer4_14 PF13394.1 CDI82714.1 - 6.1e-06 26.2 0.0 0.00012 22.1 0.0 2.2 1 1 1 2 2 2 1 4Fe-4S single cluster domain Secretin_N PF03958.12 CDI82715.1 - 0.025 14.7 2.9 4.7 7.4 2.0 2.6 1 1 0 1 1 1 0 Bacterial type II/III secretion system short domain Phe_tRNA-synt_N PF02912.13 CDI82715.1 - 0.032 13.9 4.6 4.1 7.2 0.1 3.2 3 0 0 3 3 3 0 Aminoacyl tRNA synthetase class II, N-terminal domain ATP-synt_E PF05680.7 CDI82715.1 - 0.29 11.1 5.9 5.1 7.1 0.7 2.7 2 1 1 3 3 3 0 ATP synthase E chain DUF1778 PF08681.6 CDI82715.1 - 1.4 8.8 4.4 26 4.7 0.2 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF1778) Herpes_UL87 PF03043.9 CDI82722.1 - 0.0018 16.7 7.1 0.0018 16.7 4.9 2.2 1 1 1 2 2 2 1 Herpesvirus UL87 family Med15 PF09606.5 CDI82723.1 - 6.1e-06 24.7 106.9 6.1e-06 24.7 74.1 3.9 1 1 1 3 3 3 1 ARC105 or Med15 subunit of Mediator complex non-fungal Ribosomal_60s PF00428.14 CDI82723.1 - 1.6 9.1 59.2 0.74 10.2 1.5 6.2 6 0 0 6 6 6 0 60s Acidic ribosomal protein FCP1_C PF09309.5 CDI82730.1 - 0.0047 16.2 4.4 0.0047 16.2 3.1 6.1 3 2 1 5 5 5 2 FCP1, C-terminal DUF2126 PF09899.4 CDI82732.1 - 0.19 9.7 23.9 0.0042 15.2 11.4 1.8 2 0 0 2 2 2 0 Putative amidoligase enzyme (DUF2126) C2 PF00168.25 CDI82736.1 - 5.5e-13 48.5 0.0 1.3e-12 47.3 0.0 1.7 1 0 0 1 1 1 1 C2 domain WD40_alt PF14077.1 CDI82736.1 - 0.15 11.6 3.4 7.8 6.2 0.1 2.6 2 0 0 2 2 2 0 Alternative WD40 repeat motif M PF02370.11 CDI82736.1 - 4.5 7.9 4.6 60 4.5 0.2 2.9 3 0 0 3 3 3 0 M protein repeat Ribosomal_L29 PF00831.18 CDI82736.1 - 7.7 6.2 9.3 14 5.4 0.9 2.5 1 1 1 2 2 2 0 Ribosomal L29 protein Med15 PF09606.5 CDI82739.1 - 0.017 13.3 106.0 0.02 13.1 73.4 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal GHL12 PF14882.1 CDI82739.1 - 0.32 11.1 0.2 0.32 11.1 0.1 2.7 2 1 0 2 2 2 0 Hypothetical glycosyl hydrolase 12 MSP1_C PF07462.6 CDI82739.1 - 3 6.1 11.7 4.4 5.5 8.1 1.2 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus MMR_HSR1 PF01926.18 CDI82740.1 - 6.2e-10 39.0 0.0 1.5e-09 37.8 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_21 PF13304.1 CDI82740.1 - 0.014 15.4 0.0 0.019 14.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain GTP1_OBG PF01018.17 CDI82740.1 - 0.027 14.1 0.0 0.027 14.1 0.0 2.0 2 1 1 3 3 3 0 GTP1/OBG Miro PF08477.8 CDI82740.1 - 0.094 13.2 0.0 0.094 13.2 0.0 3.0 2 1 1 3 3 3 0 Miro-like protein DUF2813 PF11398.3 CDI82740.1 - 0.23 10.4 0.0 0.23 10.4 0.0 3.1 2 1 2 4 4 4 0 Protein of unknown function (DUF2813) Zip PF02535.17 CDI82740.1 - 0.26 10.2 14.0 0.4 9.6 9.7 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter AAA_23 PF13476.1 CDI82740.1 - 0.98 9.7 0.0 0.98 9.7 0.0 3.2 2 1 0 2 2 2 0 AAA domain Hid1 PF12722.2 CDI82740.1 - 3.2 5.2 35.9 4.1 4.9 24.9 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein GAGA_bind PF06217.7 CDI82740.1 - 4.1 7.2 32.7 5.7 6.8 22.7 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family ASFV_J13L PF05568.6 CDI82742.1 - 0.02 14.4 1.6 0.02 14.4 1.1 1.1 1 0 0 1 1 1 0 African swine fever virus J13L protein Ribosomal_60s PF00428.14 CDI82742.1 - 1.3 9.4 10.1 2.4 8.6 7.0 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein Med15 PF09606.5 CDI82743.1 - 0.0006 18.1 48.5 0.0056 14.9 14.9 2.2 2 0 0 2 2 2 2 ARC105 or Med15 subunit of Mediator complex non-fungal Ctr PF04145.10 CDI82743.1 - 0.019 15.0 2.3 0.019 15.0 1.6 4.2 1 1 1 2 2 2 0 Ctr copper transporter family Synuclein PF01387.12 CDI82743.1 - 0.038 13.8 0.1 0.038 13.8 0.1 3.4 3 0 0 3 3 3 0 Synuclein CENP-B_dimeris PF09026.5 CDI82743.1 - 0.089 13.0 0.4 0.089 13.0 0.3 3.1 3 0 0 3 3 3 0 Centromere protein B dimerisation domain Activator_LAG-3 PF11498.3 CDI82743.1 - 0.6 8.7 67.0 0.29 9.8 19.0 2.5 2 0 0 2 2 2 0 Transcriptional activator LAG-3 TFIIA PF03153.8 CDI82743.1 - 1.8 8.3 49.8 3 7.6 13.7 2.3 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit PT-VENN PF04829.8 CDI82743.1 - 6.9 6.3 26.2 0.29 10.7 12.9 2.8 2 0 0 2 2 2 0 Pre-toxin domain with VENN motif Mpp10 PF04006.7 CDI82745.1 - 0.88 7.8 28.0 0.93 7.7 19.4 1.0 1 0 0 1 1 1 0 Mpp10 protein Spore_coat_CotO PF14153.1 CDI82745.1 - 1.1 8.7 27.2 1.2 8.5 18.9 1.0 1 0 0 1 1 1 0 Spore coat protein CotO DUF1510 PF07423.6 CDI82745.1 - 1.7 7.9 33.1 1.9 7.8 22.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) CDC27 PF09507.5 CDI82745.1 - 4.4 6.4 29.1 4.6 6.3 20.1 1.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 SprA-related PF12118.3 CDI82745.1 - 4.6 6.4 22.4 5.4 6.2 15.5 1.1 1 0 0 1 1 1 0 SprA-related family FAM60A PF15396.1 CDI82745.1 - 5.6 6.6 8.5 6.5 6.4 5.9 1.0 1 0 0 1 1 1 0 Protein Family FAM60A TP53IP5 PF15331.1 CDI82745.1 - 6.4 6.6 14.7 7.4 6.4 10.2 1.0 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 Spore_YhcN_YlaJ PF09580.5 CDI82745.1 - 7.2 6.6 14.2 8.5 6.4 9.8 1.0 1 0 0 1 1 1 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) Nop14 PF04147.7 CDI82745.1 - 7.6 4.3 32.1 8.1 4.2 22.3 1.0 1 0 0 1 1 1 0 Nop14-like family DUF4045 PF13254.1 CDI82745.1 - 8.5 5.5 20.5 9.9 5.3 14.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Caldesmon PF02029.10 CDI82745.1 - 8.9 4.6 34.8 9.8 4.4 24.1 1.0 1 0 0 1 1 1 0 Caldesmon Vfa1 PF08432.5 CDI82745.1 - 9.1 6.2 21.8 11 5.9 15.1 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Bax1-I PF01027.15 CDI82747.1 - 0.067 12.7 1.3 0.1 12.1 0.9 1.3 1 0 0 1 1 1 0 Inhibitor of apoptosis-promoting Bax1 PAT1 PF09770.4 CDI82774.1 - 2e-05 23.0 79.4 0.00014 20.2 43.0 2.2 2 0 0 2 2 2 2 Topoisomerase II-associated protein PAT1 Med15 PF09606.5 CDI82774.1 - 0.0004 18.7 107.4 0.012 13.8 8.9 2.1 2 0 0 2 2 2 2 ARC105 or Med15 subunit of Mediator complex non-fungal AAA_23 PF13476.1 CDI82774.1 - 0.00069 19.9 25.9 0.00069 19.9 18.0 3.4 2 1 1 3 3 3 1 AAA domain DUF883 PF05957.8 CDI82774.1 - 0.0038 17.5 2.9 0.0038 17.5 2.0 6.4 6 1 1 7 7 7 2 Bacterial protein of unknown function (DUF883) YtxH PF12732.2 CDI82774.1 - 0.013 15.8 2.4 0.013 15.8 1.7 5.3 4 2 0 4 4 4 0 YtxH-like protein SOBP PF15279.1 CDI82774.1 - 2.7 8.3 38.8 8.5 6.6 22.7 2.4 2 0 0 2 2 2 0 Sine oculis-binding protein XRN_N PF03159.13 CDI82775.1 - 1.8e-68 230.4 0.0 2.9e-68 229.8 0.0 1.3 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus Thymosin PF01290.15 CDI82777.1 - 0.036 13.6 0.1 0.099 12.2 0.1 1.8 1 0 0 1 1 1 0 Thymosin beta-4 family FHA PF00498.21 CDI82777.1 - 0.054 13.6 0.0 0.14 12.2 0.0 1.7 1 0 0 1 1 1 0 FHA domain EF-hand_7 PF13499.1 CDI82781.1 - 5.8e-17 61.5 0.0 1.2e-07 31.6 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 CDI82781.1 - 1.4e-15 55.3 0.0 0.0031 16.7 0.0 4.3 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.1 CDI82781.1 - 5.8e-13 47.5 0.0 0.0042 16.8 0.0 4.1 4 0 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.1 CDI82781.1 - 1.7e-10 39.7 0.0 0.02 14.2 0.0 4.2 4 0 0 4 4 4 3 EF hand EF-hand_9 PF14658.1 CDI82781.1 - 1.7e-07 31.0 0.0 0.00043 20.1 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.1 CDI82781.1 - 4.1e-07 29.5 0.4 0.53 9.9 0.0 4.0 3 1 1 4 4 4 2 EF-hand domain pair Beta_protein PF14350.1 CDI82781.1 - 0.1 11.7 0.0 0.12 11.5 0.0 1.1 1 0 0 1 1 1 0 Beta protein VIT1 PF01988.14 CDI82782.1 - 6.6e-66 221.8 0.8 7.9e-66 221.5 0.6 1.1 1 0 0 1 1 1 1 VIT family DUF599 PF04654.7 CDI82782.1 - 0.0033 16.5 0.0 0.0055 15.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF599 DUF4064 PF13273.1 CDI82782.1 - 2.5 8.2 9.3 1.5 8.9 2.0 2.6 2 2 1 3 3 3 0 Protein of unknown function (DUF4064) Tetraspannin PF00335.15 CDI82782.1 - 3.8 6.7 6.6 23 4.1 4.3 2.1 2 0 0 2 2 2 0 Tetraspanin family DUF1700 PF08006.6 CDI82782.1 - 7.6 5.7 6.8 3.9 6.7 1.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1700) SNF PF00209.13 CDI82783.1 - 1.2e-20 73.4 32.5 1.2e-20 73.4 22.6 2.4 2 1 0 2 2 2 2 Sodium:neurotransmitter symporter family WES_acyltransf PF03007.11 CDI82786.1 - 3.1e-05 23.6 0.1 0.00012 21.7 0.1 2.0 1 1 0 1 1 1 1 Wax ester synthase-like Acyl-CoA acyltransferase domain Suf PF05843.9 CDI82787.1 - 0.00096 18.9 2.2 0.00096 18.9 1.5 1.1 1 0 0 1 1 1 1 Suppressor of forked protein (Suf) FimP PF09766.4 CDI82787.1 - 0.00099 18.2 5.6 0.0011 18.0 3.9 1.1 1 0 0 1 1 1 1 Fms-interacting protein Pex14_N PF04695.8 CDI82787.1 - 0.0016 18.4 2.4 0.0024 17.9 1.7 1.4 1 0 0 1 1 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF775 PF05603.7 CDI82787.1 - 0.0023 17.4 2.8 0.0027 17.2 1.9 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF775) Spt20 PF12090.3 CDI82787.1 - 0.0048 16.2 2.8 0.0055 16.0 1.9 1.2 1 0 0 1 1 1 1 Spt20 family BRF1 PF07741.8 CDI82787.1 - 0.0071 16.5 0.2 0.01 16.0 0.2 1.4 1 0 0 1 1 1 1 Brf1-like TBP-binding domain Med15 PF09606.5 CDI82787.1 - 0.01 14.1 20.3 0.011 13.9 14.0 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF1764 PF08576.5 CDI82787.1 - 0.011 16.5 1.1 0.013 16.2 0.7 1.3 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) Cwf_Cwc_15 PF04889.7 CDI82787.1 - 0.016 14.9 5.7 0.021 14.5 3.9 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Pex26 PF07163.7 CDI82787.1 - 0.027 13.3 3.7 0.034 13.0 2.6 1.1 1 0 0 1 1 1 0 Pex26 protein Band_3_cyto PF07565.8 CDI82787.1 - 0.029 13.8 1.7 0.036 13.5 1.2 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain PAT1 PF09770.4 CDI82787.1 - 0.034 12.4 14.1 0.036 12.3 9.8 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 LIM_bind PF01803.11 CDI82787.1 - 0.069 12.2 5.6 0.092 11.8 3.9 1.1 1 0 0 1 1 1 0 LIM-domain binding protein Apc1 PF12859.2 CDI82787.1 - 0.074 13.2 2.2 0.11 12.7 1.6 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 1 DUF912 PF06024.7 CDI82787.1 - 0.077 13.0 0.1 0.13 12.3 0.1 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF4407 PF14362.1 CDI82787.1 - 0.11 11.4 8.8 0.13 11.1 6.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) RAB3GAP2_N PF14655.1 CDI82787.1 - 0.11 11.4 5.6 0.15 11.0 3.9 1.2 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus ATG22 PF11700.3 CDI82787.1 - 0.13 10.7 0.4 0.16 10.4 0.3 1.0 1 0 0 1 1 1 0 Vacuole effluxer Atg22 like DUF4557 PF15101.1 CDI82787.1 - 0.15 11.8 8.6 0.2 11.4 6.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) OmpH PF03938.9 CDI82787.1 - 0.19 11.6 21.0 0.3 11.0 14.6 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Ctr PF04145.10 CDI82787.1 - 0.23 11.4 1.9 0.34 10.9 1.3 1.4 1 0 0 1 1 1 0 Ctr copper transporter family TFIIA PF03153.8 CDI82787.1 - 0.26 11.1 13.1 0.3 10.9 9.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit BaxI_1 PF12811.2 CDI82787.1 - 0.39 9.8 2.2 0.58 9.2 1.5 1.3 1 0 0 1 1 1 0 Bax inhibitor 1 like DUF4199 PF13858.1 CDI82787.1 - 0.66 9.8 4.8 1.1 9.1 3.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) DUF4175 PF13779.1 CDI82787.1 - 0.68 7.5 20.1 0.85 7.2 13.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) FLO_LFY PF01698.11 CDI82787.1 - 0.73 8.6 6.5 0.91 8.3 4.5 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein Activator_LAG-3 PF11498.3 CDI82787.1 - 1.4 7.5 30.2 1.9 7.1 20.9 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 RskA PF10099.4 CDI82787.1 - 1.6 8.4 12.9 1.9 8.2 7.2 1.9 1 1 1 2 2 2 0 Anti-sigma-K factor rskA APC_CDC26 PF10471.4 CDI82787.1 - 1.7 9.4 18.6 4.1 8.2 12.9 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex APC subunit 1 Gag_spuma PF03276.9 CDI82787.1 - 2.3 6.4 13.4 3.2 5.9 9.3 1.2 1 0 0 1 1 1 0 Spumavirus gag protein FCP1_C PF09309.5 CDI82787.1 - 2.3 7.4 9.3 3.4 6.8 6.5 1.2 1 0 0 1 1 1 0 FCP1, C-terminal UPF0560 PF10577.4 CDI82787.1 - 2.4 6.3 10.8 2.8 6.0 7.5 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 DivIC PF04977.10 CDI82787.1 - 2.8 7.5 13.2 4.7 6.7 9.1 1.4 1 0 0 1 1 1 0 Septum formation initiator DUF3373 PF11853.3 CDI82787.1 - 5.4 5.4 7.6 6.7 5.1 5.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) DUF202 PF02656.10 CDI82794.1 - 4.4e-12 46.0 6.6 4.4e-12 46.0 4.6 5.6 6 1 0 6 6 6 1 Domain of unknown function (DUF202) VTC PF09359.5 CDI82794.1 - 2.4e-11 43.1 0.0 4.8e-11 42.2 0.0 1.5 1 0 0 1 1 1 1 VTC domain TRC8_N PF13705.1 CDI82795.1 - 5.6 5.4 4.5 16 3.9 3.1 1.8 1 0 0 1 1 1 0 TRC8 N-terminal domain MOZART1 PF12554.3 CDI82796.1 - 0.04 13.3 0.2 0.079 12.4 0.1 1.4 1 0 0 1 1 1 0 Mitotic-spindle organizing gamma-tubulin ring associated DUF2526 PF10735.4 CDI82797.1 - 2.9 7.9 8.1 1.7 8.6 3.4 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2526) DUF4407 PF14362.1 CDI82797.1 - 6.6 5.6 12.7 7.2 5.4 8.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Apc15p PF05841.6 CDI82797.1 - 7.5 7.2 18.5 7.9 7.2 12.9 1.0 1 0 0 1 1 1 0 Apc15p protein DUF1426 PF07234.6 CDI82797.1 - 8 6.2 6.9 10 5.8 4.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1426) NARP1 PF12569.3 CDI82797.1 - 8.9 4.9 11.5 8.4 5.0 8.0 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 RPOL_N PF14700.1 CDI82799.1 - 0.41 9.8 4.9 0.44 9.7 3.4 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase N-terminal GAGA_bind PF06217.7 CDI82803.1 - 0.8 9.6 33.0 1 9.2 22.9 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family PAP2 PF01569.16 CDI82813.1 - 0.64 9.7 2.8 0.63 9.7 0.9 1.7 1 1 1 2 2 2 0 PAP2 superfamily Med3 PF11593.3 CDI82813.1 - 3.5 6.7 23.2 4 6.5 16.1 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal THRAP3_BCLAF1 PF15440.1 CDI82815.1 - 0.046 12.3 16.2 0.059 12.0 11.2 1.1 1 0 0 1 1 1 0 THRAP3/BCLAF1 family SOBP PF15279.1 CDI82815.1 - 0.29 11.4 13.3 0.4 11.0 9.2 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein AvrE PF11725.3 CDI82815.1 - 1 6.3 22.7 1.3 6.0 15.8 1.0 1 0 0 1 1 1 0 Pathogenicity factor CytochromB561_N PF09786.4 CDI82815.1 - 1.7 6.9 17.1 2.1 6.6 11.9 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal Macoilin PF09726.4 CDI82815.1 - 2.6 6.1 24.2 4.4 5.4 16.8 1.4 1 0 0 1 1 1 0 Transmembrane protein IBB PF01749.15 CDI82815.1 - 3.3 7.9 9.5 0.11 12.7 1.3 2.3 2 0 0 2 2 2 0 Importin beta binding domain Tmemb_cc2 PF10267.4 CDI82815.1 - 5.8 5.3 15.1 7.5 5.0 10.5 1.2 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein PAP1 PF08601.5 CDI82815.1 - 8.6 5.9 24.7 12 5.4 17.1 1.2 1 0 0 1 1 1 0 Transcription factor PAP1 RIC3 PF15361.1 CDI82817.1 - 0.0047 17.1 0.7 0.0047 17.1 0.5 12.8 8 3 4 13 13 13 1 Resistance to inhibitors of cholinesterase homologue 3 PBP1_TM PF14812.1 CDI82818.1 - 0.013 15.7 7.0 0.013 15.7 4.8 3.4 2 1 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Daxx PF03344.10 CDI82818.1 - 0.91 7.9 62.4 0.053 12.0 8.6 2.1 2 0 0 2 2 2 0 Daxx Family SAPS PF04499.10 CDI82818.1 - 0.95 8.0 62.1 0.074 11.6 9.1 2.1 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein PLRV_ORF5 PF01690.12 CDI82818.1 - 1.8 7.6 63.2 0.33 10.0 9.0 2.1 2 0 0 2 2 2 0 Potato leaf roll virus readthrough protein Pilt PF15453.1 CDI82818.1 - 2.4 7.7 62.1 0.38 10.3 24.5 2.3 2 0 0 2 2 2 0 Protein incorporated later into Tight Junctions DUF1777 PF08648.7 CDI82818.1 - 4.2 7.0 51.0 3.1 7.5 7.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1777) Utp14 PF04615.8 CDI82818.1 - 6.9 4.7 85.4 0.055 11.6 32.6 2.0 2 0 0 2 2 2 0 Utp14 protein CBF PF03914.12 CDI82819.1 - 0.00017 21.0 0.7 0.00032 20.2 0.5 1.5 1 0 0 1 1 1 1 CBF/Mak21 family Nop53 PF07767.6 CDI82819.1 - 0.63 8.9 15.1 1.1 8.1 10.4 1.3 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) TRC8_N PF13705.1 CDI82820.1 - 0.18 10.3 0.9 0.39 9.2 0.6 1.5 1 0 0 1 1 1 0 TRC8 N-terminal domain CRT10 PF08728.5 CDI82820.1 - 5.3 4.9 28.0 0.55 8.1 11.5 2.3 2 0 0 2 2 2 0 CRT10 Herpes_UL87 PF03043.9 CDI82821.1 - 0.39 9.0 5.7 0.4 9.0 3.9 1.2 1 0 0 1 1 1 0 Herpesvirus UL87 family Activator_LAG-3 PF11498.3 CDI82821.1 - 2.3 6.8 22.8 3.2 6.3 15.8 1.3 1 0 0 1 1 1 0 Transcriptional activator LAG-3 IncA PF04156.9 CDI82823.1 - 3.7e-05 23.4 14.1 4.9e-05 23.0 9.8 1.2 1 0 0 1 1 1 1 IncA protein AAA_23 PF13476.1 CDI82823.1 - 0.27 11.5 15.5 0.23 11.7 10.8 1.1 1 0 0 1 1 1 0 AAA domain FimP PF09766.4 CDI82823.1 - 0.44 9.5 28.7 0.61 9.0 19.9 1.3 1 0 0 1 1 1 0 Fms-interacting protein Serinc PF03348.10 CDI82823.1 - 0.47 9.1 16.7 0.5 9.0 11.6 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) DUF1980 PF09323.5 CDI82823.1 - 0.51 10.0 11.0 0.62 9.7 7.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) DUF2217 PF10265.4 CDI82823.1 - 0.53 8.9 10.6 0.6 8.8 7.3 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) Med15 PF09606.5 CDI82823.1 - 0.54 8.3 54.0 0.72 7.9 37.4 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal PPP4R2 PF09184.6 CDI82823.1 - 0.68 9.4 16.2 0.7 9.3 11.2 1.1 1 0 0 1 1 1 0 PPP4R2 Band_3_cyto PF07565.8 CDI82823.1 - 0.76 9.2 15.6 0.75 9.2 10.8 1.3 1 0 0 1 1 1 0 Band 3 cytoplasmic domain DUF2215 PF10225.4 CDI82823.1 - 0.94 8.8 11.3 1.1 8.6 7.8 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) Suf PF05843.9 CDI82823.1 - 1 9.0 27.4 1.3 8.6 19.0 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Zip PF02535.17 CDI82823.1 - 1.1 8.2 8.8 1.3 7.9 6.1 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter MARCKS PF02063.12 CDI82823.1 - 1.2 8.9 33.8 1.5 8.6 23.4 1.1 1 0 0 1 1 1 0 MARCKS family DUF2232 PF09991.4 CDI82823.1 - 1.3 7.9 6.4 1.7 7.5 4.4 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) CAF-1_p150 PF11600.3 CDI82823.1 - 1.4 8.2 29.4 1.6 8.0 20.4 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Folate_carrier PF01770.13 CDI82823.1 - 1.5 7.2 9.5 1.6 7.1 6.6 1.2 1 0 0 1 1 1 0 Reduced folate carrier FLO_LFY PF01698.11 CDI82823.1 - 1.8 7.3 25.0 1.9 7.2 17.3 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein Peptidase_S49_N PF08496.5 CDI82823.1 - 1.8 8.3 14.9 2.2 8.0 10.3 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Apt1 PF10351.4 CDI82823.1 - 1.9 7.2 13.4 1.9 7.2 9.3 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain CDC45 PF02724.9 CDI82823.1 - 2.3 6.1 17.6 2.2 6.2 12.2 1.1 1 0 0 1 1 1 0 CDC45-like protein F-protein PF00469.15 CDI82823.1 - 2.4 7.4 14.6 2.3 7.5 10.1 1.2 1 0 0 1 1 1 0 Negative factor, (F-Protein) or Nef DDHD PF02862.12 CDI82823.1 - 2.5 7.8 21.8 2.9 7.6 15.1 1.2 1 0 0 1 1 1 0 DDHD domain DUF4446 PF14584.1 CDI82823.1 - 2.7 7.8 9.0 3.5 7.4 6.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) PBP_sp32 PF07222.7 CDI82823.1 - 2.7 7.0 28.2 3.1 6.8 19.5 1.0 1 0 0 1 1 1 0 Proacrosin binding protein sp32 SID-1_RNA_chan PF13965.1 CDI82823.1 - 2.8 5.9 9.6 2.6 6.0 6.6 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 SprA-related PF12118.3 CDI82823.1 - 3.8 6.7 54.1 4.8 6.4 37.5 1.1 1 0 0 1 1 1 0 SprA-related family NPR3 PF03666.8 CDI82823.1 - 4.2 5.7 16.9 4.4 5.7 11.7 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Bac_luciferase PF00296.15 CDI82823.1 - 4.3 6.3 15.6 5.3 6.0 10.8 1.1 1 0 0 1 1 1 0 Luciferase-like monooxygenase Raftlin PF15250.1 CDI82823.1 - 4.6 5.6 20.4 4.7 5.6 14.2 1.1 1 0 0 1 1 1 0 Raftlin HemX PF04375.9 CDI82823.1 - 4.9 5.6 40.8 5.4 5.4 28.3 1.0 1 0 0 1 1 1 0 HemX Activator_LAG-3 PF11498.3 CDI82823.1 - 4.9 5.7 49.3 6.8 5.3 34.2 1.3 1 0 0 1 1 1 0 Transcriptional activator LAG-3 SPX PF03105.14 CDI82823.1 - 5.1 6.7 19.2 5.3 6.7 13.3 1.1 1 0 0 1 1 1 0 SPX domain DUF1510 PF07423.6 CDI82823.1 - 5.2 6.3 24.7 5.8 6.2 17.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Paf1 PF03985.8 CDI82823.1 - 5.6 5.5 23.2 6.1 5.4 16.1 1.1 1 0 0 1 1 1 0 Paf1 UPF0560 PF10577.4 CDI82823.1 - 6 4.9 22.6 6.6 4.8 15.6 1.3 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 AMP-binding PF00501.23 CDI82823.1 - 6.2 5.1 8.2 7 4.9 5.7 1.0 1 0 0 1 1 1 0 AMP-binding enzyme MSP1_C PF07462.6 CDI82823.1 - 7.3 4.8 17.7 8.6 4.6 12.3 1.0 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus eIF-3_zeta PF05091.7 CDI82823.1 - 9.2 4.7 26.8 9.3 4.7 18.6 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) AAT PF03417.11 CDI82823.1 - 9.6 5.5 16.6 11 5.3 11.5 1.1 1 0 0 1 1 1 0 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase Oleosin PF01277.12 CDI82823.1 - 9.9 5.7 11.7 18 4.8 7.8 1.8 1 1 0 1 1 1 0 Oleosin Ycf1 PF05758.7 CDI82834.1 - 0.077 10.6 25.7 0.082 10.6 4.2 2.1 2 0 0 2 2 2 0 Ycf1 Spore_coat_CotO PF14153.1 CDI82834.1 - 9.2 5.6 53.5 0.54 9.6 14.5 3.0 3 1 0 3 3 3 0 Spore coat protein CotO DUF2453 PF10507.4 CDI82837.1 - 6.8e-07 29.0 0.9 6.8e-07 29.0 0.6 2.9 2 1 0 2 2 2 1 Protein of unknown function (DUF2453) Kinase-like PF14531.1 CDI82847.1 - 2e-06 26.9 0.0 7.3e-06 25.1 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Hen1_L PF12623.2 CDI82847.1 - 0.022 13.5 0.0 0.04 12.7 0.0 1.3 1 0 0 1 1 1 0 RNA repair, ligase-Pnkp-associating, region of Hen1 Pkinase PF00069.20 CDI82847.1 - 0.069 12.2 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein kinase domain Na_H_Exchanger PF00999.16 CDI82848.1 - 0.015 13.8 0.1 0.015 13.8 0.0 1.9 2 0 0 2 2 2 0 Sodium/hydrogen exchanger family Chromo PF00385.19 CDI82849.1 - 5e-15 54.9 0.1 8.4e-15 54.1 0.1 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain RVT_1 PF00078.22 CDI82850.1 - 1.7e-14 53.7 0.0 3.2e-14 52.8 0.0 1.5 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 CDI82850.1 - 8.5e-09 35.5 0.0 1.7e-08 34.5 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain DUF1906 PF08924.6 CDI82855.1 - 0.37 10.6 3.2 0.49 10.2 2.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1906) DUF1517 PF07466.6 CDI82858.1 - 0.0015 17.5 2.9 0.0018 17.3 2.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1517) Rax2 PF12768.2 CDI82858.1 - 0.013 14.7 0.9 0.015 14.4 0.6 1.1 1 0 0 1 1 1 0 Cortical protein marker for cell polarity DUF4228 PF14009.1 CDI82858.1 - 0.85 9.7 10.3 1 9.4 7.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4228) Corona_nucleoca PF00937.13 CDI82858.1 - 2.2 7.1 16.2 2.5 6.9 11.2 1.0 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein SSP160 PF06933.6 CDI82858.1 - 9.3 4.0 16.1 9.5 4.0 11.2 1.0 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Secretin_N_2 PF07655.8 CDI82858.1 - 9.8 6.6 21.4 2.3 8.6 12.0 1.8 2 0 0 2 2 2 0 Secretin N-terminal domain DUF508 PF04370.7 CDI82858.1 - 10 5.7 17.0 22 4.6 11.8 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF508) PKK PF12474.3 CDI82859.1 - 9 6.0 28.7 24 4.6 9.0 2.3 1 1 1 2 2 2 0 Polo kinase kinase Rep_fac_C PF08542.6 CDI82882.1 - 3.9e-10 39.5 0.0 5.2e-10 39.1 0.0 1.2 1 0 0 1 1 1 1 Replication factor C C-terminal domain Rad17 PF03215.10 CDI82882.1 - 0.12 10.9 0.0 0.16 10.5 0.0 1.1 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein DUF755 PF05501.6 CDI82886.1 - 0.013 15.5 7.8 0.013 15.5 5.4 10.6 8 2 1 9 9 9 0 Domain of unknown function (DUF755) Ycf1 PF05758.7 CDI82898.1 - 0.03 12.0 2.7 0.035 11.8 1.9 1.1 1 0 0 1 1 1 0 Ycf1 CAF-1_p150 PF11600.3 CDI82898.1 - 0.063 12.6 17.8 0.13 11.6 12.3 1.5 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Band_3_cyto PF07565.8 CDI82898.1 - 0.21 11.0 8.6 0.1 12.0 4.6 1.5 1 1 1 2 2 2 0 Band 3 cytoplasmic domain PAT1 PF09770.4 CDI82898.1 - 0.35 9.0 26.3 0.47 8.6 18.2 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 AAA_23 PF13476.1 CDI82898.1 - 0.81 9.9 9.9 1.1 9.5 6.9 1.2 1 0 0 1 1 1 0 AAA domain UPF0560 PF10577.4 CDI82898.1 - 1.4 7.0 16.6 1.9 6.6 11.5 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 MFS_1 PF07690.11 CDI82899.1 - 3.5e-23 81.9 33.9 3.5e-23 81.9 23.5 2.3 2 1 1 3 3 3 2 Major Facilitator Superfamily W2 PF02020.13 CDI82901.1 - 0.11 12.5 0.2 3.6 7.6 0.0 2.1 2 0 0 2 2 2 0 eIF4-gamma/eIF5/eIF2-epsilon IncA PF04156.9 CDI82904.1 - 0.0011 18.5 11.8 0.0013 18.4 8.2 1.3 1 0 0 1 1 1 1 IncA protein AAA_23 PF13476.1 CDI82904.1 - 0.027 14.8 11.7 0.024 14.9 8.1 1.1 1 0 0 1 1 1 0 AAA domain CD20 PF04103.10 CDI82904.1 - 0.042 13.7 0.5 0.053 13.4 0.3 1.2 1 0 0 1 1 1 0 CD20-like family FimP PF09766.4 CDI82904.1 - 0.056 12.5 20.3 0.065 12.2 14.1 1.1 1 0 0 1 1 1 0 Fms-interacting protein Med15 PF09606.5 CDI82904.1 - 0.063 11.4 38.6 0.068 11.3 26.7 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Band_3_cyto PF07565.8 CDI82904.1 - 0.12 11.8 7.2 0.12 11.8 5.0 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain zf-DHHC PF01529.15 CDI82904.1 - 0.13 11.6 1.5 0.11 11.8 1.0 1.1 1 0 0 1 1 1 0 DHHC palmitoyltransferase DUF3357 PF11837.3 CDI82904.1 - 0.16 11.8 5.2 0.21 11.4 3.1 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF3357) DUF4366 PF14283.1 CDI82904.1 - 0.17 11.3 8.9 0.19 11.1 6.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) FHIPEP PF00771.15 CDI82904.1 - 0.18 10.1 14.9 0.19 9.9 10.3 1.0 1 0 0 1 1 1 0 FHIPEP family SR-25 PF10500.4 CDI82904.1 - 0.18 11.2 14.0 0.22 10.9 9.7 1.0 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Hid1 PF12722.2 CDI82904.1 - 0.19 9.3 6.2 0.16 9.6 4.3 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein PAT1 PF09770.4 CDI82904.1 - 0.44 8.7 28.4 0.48 8.6 19.7 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Bac_luciferase PF00296.15 CDI82904.1 - 0.44 9.6 32.0 0.5 9.4 22.2 1.0 1 0 0 1 1 1 0 Luciferase-like monooxygenase Folate_carrier PF01770.13 CDI82904.1 - 0.51 8.7 3.5 0.47 8.9 2.4 1.1 1 0 0 1 1 1 0 Reduced folate carrier DDHD PF02862.12 CDI82904.1 - 0.54 10.0 10.5 0.57 9.9 7.3 1.2 1 0 0 1 1 1 0 DDHD domain Glt_symporter PF03616.9 CDI82904.1 - 0.63 8.4 5.4 0.73 8.2 3.8 1.1 1 0 0 1 1 1 0 Sodium/glutamate symporter DUF2232 PF09991.4 CDI82904.1 - 0.68 8.8 4.3 0.73 8.7 3.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) Serinc PF03348.10 CDI82904.1 - 1 8.0 10.8 1 8.0 7.5 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) OATP PF03137.15 CDI82904.1 - 1 7.3 6.0 1.1 7.1 4.1 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family GAGA_bind PF06217.7 CDI82904.1 - 1.5 8.7 16.3 1.5 8.6 11.3 1.0 1 0 0 1 1 1 0 GAGA binding protein-like family VIT1 PF01988.14 CDI82904.1 - 2.3 7.6 12.9 0.26 10.7 5.9 1.6 1 1 1 2 2 2 0 VIT family DUF913 PF06025.7 CDI82904.1 - 2.8 6.5 9.0 2.9 6.5 6.2 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Neur_chan_memb PF02932.11 CDI82904.1 - 2.9 7.7 6.8 3.3 7.5 4.7 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region CDK5_activator PF03261.10 CDI82904.1 - 3.7 6.7 11.1 4 6.6 7.7 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein EphA2_TM PF14575.1 CDI82904.1 - 4.4 7.7 7.6 12 6.3 5.2 1.8 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain RR_TM4-6 PF06459.7 CDI82904.1 - 5.1 6.8 13.9 5.3 6.8 9.6 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF2215 PF10225.4 CDI82904.1 - 5.5 6.3 5.6 6.1 6.2 3.8 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) Herpes_UL87 PF03043.9 CDI82904.1 - 6.8 4.9 13.2 7.9 4.7 9.2 1.1 1 0 0 1 1 1 0 Herpesvirus UL87 family Hamartin PF04388.7 CDI82904.1 - 7 5.2 12.4 7.8 5.0 8.6 1.0 1 0 0 1 1 1 0 Hamartin protein FAM60A PF15396.1 CDI82904.1 - 7.7 6.1 10.9 9.2 5.9 7.6 1.2 1 0 0 1 1 1 0 Protein Family FAM60A FAM222A PF15258.1 CDI82904.1 - 8.4 5.4 26.3 9.4 5.3 18.2 1.1 1 0 0 1 1 1 0 Protein family of FAM222A DUF1675 PF07897.6 CDI82904.1 - 8.8 6.0 12.7 10 5.8 8.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) TFIIA PF03153.8 CDI82906.1 - 0.47 10.2 28.0 0.53 10.1 19.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PAT1 PF09770.4 CDI82906.1 - 0.53 8.4 13.7 0.61 8.2 9.5 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Hamartin PF04388.7 CDI82906.1 - 7 5.1 11.8 8.8 4.8 8.2 1.2 1 0 0 1 1 1 0 Hamartin protein Parvo_coat PF00740.13 CDI82906.1 - 8.1 5.2 11.4 9.5 5.0 7.9 1.0 1 0 0 1 1 1 0 Parvovirus coat protein VP2 RRM_1 PF00076.17 CDI82909.1 - 1.1e-06 28.1 1.7 1.2e-06 28.0 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CDI82909.1 - 0.0021 17.8 0.8 0.0042 16.9 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CDI82909.1 - 0.0051 16.7 3.2 0.018 14.9 0.0 2.5 3 0 0 3 3 3 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Rtf2 PF04641.7 CDI82909.1 - 0.0086 15.3 4.4 0.011 14.9 3.0 1.1 1 0 0 1 1 1 1 Rtf2 RING-finger DUF2146 PF10220.4 CDI82909.1 - 0.36 8.7 7.7 0.46 8.4 5.3 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2146) DNA_pol_viral_N PF00242.12 CDI82909.1 - 3.4 6.5 10.9 5 6.0 7.6 1.2 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain Macoilin PF09726.4 CDI82909.1 - 6.2 4.9 18.8 10 4.2 13.1 1.2 1 0 0 1 1 1 0 Transmembrane protein RskA PF10099.4 CDI82916.1 - 0.017 14.8 0.2 0.025 14.3 0.1 1.3 1 0 0 1 1 1 0 Anti-sigma-K factor rskA Utp14 PF04615.8 CDI82918.1 - 0.9 7.6 46.4 1.1 7.3 32.2 1.0 1 0 0 1 1 1 0 Utp14 protein MIP-T3 PF10243.4 CDI82918.1 - 4 5.8 56.8 4.8 5.5 39.4 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 PAT1 PF09770.4 CDI82918.1 - 8 4.5 77.7 10 4.2 53.9 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Herpes_DNAp_acc PF04929.7 CDI82927.1 - 0.00068 18.7 0.1 0.00068 18.7 0.1 4.3 1 1 1 3 3 3 1 Herpes DNA replication accessory factor Conotoxin PF02950.12 CDI82927.1 - 0.0031 18.2 1.5 0.0031 18.2 1.0 8.7 2 1 2 4 4 4 1 Conotoxin DUF3377 PF11857.3 CDI82927.1 - 0.0038 16.8 1.1 0.0038 16.8 0.8 4.0 2 1 0 2 2 2 1 Domain of unknown function (DUF3377) TMEM154 PF15102.1 CDI82927.1 - 0.0067 16.1 12.4 0.0067 16.1 8.6 7.1 2 2 3 5 5 5 1 TMEM154 protein family SpoIIIAH PF12685.2 CDI82927.1 - 0.021 14.3 0.3 0.021 14.3 0.2 4.8 2 1 1 3 3 3 0 SpoIIIAH-like protein DUF3357 PF11837.3 CDI82927.1 - 0.12 12.2 0.1 0.12 12.2 0.1 8.5 1 1 2 5 5 5 0 Domain of unknown function (DUF3357) GRP PF07172.6 CDI82927.1 - 0.16 12.4 0.1 0.16 12.4 0.0 6.9 2 1 2 4 4 4 0 Glycine rich protein family HemX PF04375.9 CDI82928.1 - 0.0003 19.4 16.4 0.0003 19.4 11.3 2.1 1 1 1 2 2 2 1 HemX CDC27 PF09507.5 CDI82928.1 - 0.033 13.4 35.9 0.037 13.2 24.9 1.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 TFIIA PF03153.8 CDI82928.1 - 0.066 13.0 54.1 0.088 12.6 37.5 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CAF-1_p150 PF11600.3 CDI82928.1 - 0.45 9.8 49.9 0.66 9.3 34.6 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal PAT1 PF09770.4 CDI82928.1 - 0.75 7.9 77.1 0.88 7.7 53.4 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 AvrE PF11725.3 CDI82928.1 - 0.83 6.5 37.8 0.92 6.4 26.2 1.0 1 0 0 1 1 1 0 Pathogenicity factor Med15 PF09606.5 CDI82928.1 - 0.86 7.7 99.8 1.1 7.4 69.2 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal SR-25 PF10500.4 CDI82928.1 - 8.9 5.7 52.9 0.038 13.4 24.3 2.1 1 1 1 2 2 2 0 Nuclear RNA-splicing-associated protein BAF1_ABF1 PF04684.8 CDI82929.1 - 0.00021 20.3 21.6 0.00021 20.3 15.0 6.1 3 1 3 6 6 6 2 BAF1 / ABF1 chromatin reorganising factor DUF1360 PF07098.6 CDI82934.1 - 0.25 11.0 0.4 1.5 8.5 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1360) SseC PF04888.7 CDI82935.1 - 2 7.7 39.0 3.1 7.0 27.0 1.3 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family Ribosomal_60s PF00428.14 CDI82944.1 - 0.0023 18.3 3.1 0.0023 18.3 2.2 1.8 2 0 0 2 2 2 1 60s Acidic ribosomal protein Halogen_Hydrol PF10112.4 CDI82944.1 - 0.0032 16.9 7.6 0.0032 16.8 1.2 2.3 2 1 0 2 2 2 1 5-bromo-4-chloroindolyl phosphate hydrolysis protein MSP1_C PF07462.6 CDI82944.1 - 0.0063 14.9 3.5 0.0084 14.5 2.3 1.3 1 1 0 1 1 1 1 Merozoite surface protein 1 (MSP1) C-terminus Chorion_2 PF03964.10 CDI82944.1 - 0.059 13.9 1.2 0.15 12.6 0.8 1.7 1 0 0 1 1 1 0 Chorion family 2 DNA_primase_lrg PF04104.9 CDI82944.1 - 0.24 10.6 4.9 0.043 13.0 0.4 1.8 2 0 0 2 2 2 0 Eukaryotic and archaeal DNA primase, large subunit IncA PF04156.9 CDI82944.1 - 0.37 10.3 15.9 0.61 9.6 1.4 2.3 2 0 0 2 2 2 0 IncA protein DUF521 PF04412.8 CDI82944.1 - 7.4 5.0 7.1 1.1 7.7 1.4 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF521) FimP PF09766.4 CDI82958.1 - 0.0042 16.2 47.9 0.12 11.4 3.8 3.1 3 0 0 3 3 3 3 Fms-interacting protein IncA PF04156.9 CDI82958.1 - 0.0067 16.0 3.2 0.0067 16.0 2.2 3.7 3 1 0 3 3 2 1 IncA protein Ribosomal_60s PF00428.14 CDI82958.1 - 0.045 14.1 5.5 0.045 14.1 3.8 4.5 3 1 0 3 3 2 0 60s Acidic ribosomal protein EphA2_TM PF14575.1 CDI82958.1 - 0.054 13.9 0.3 0.054 13.9 0.2 4.1 3 1 0 3 3 2 0 Ephrin type-A receptor 2 transmembrane domain PH_4 PF15404.1 CDI82958.1 - 0.27 10.7 26.8 1.1 8.8 7.4 3.1 3 0 0 3 3 3 0 Pleckstrin homology domain SprA-related PF12118.3 CDI82958.1 - 0.33 10.2 78.5 0.13 11.5 24.0 3.3 3 0 0 3 3 3 0 SprA-related family PEX11 PF05648.9 CDI82958.1 - 0.37 10.0 17.6 0.17 11.0 0.4 3.2 3 0 0 3 3 3 0 Peroxisomal biogenesis factor 11 (PEX11) FAM176 PF14851.1 CDI82958.1 - 0.57 9.8 15.4 0.95 9.1 2.7 3.1 3 0 0 3 3 3 0 FAM176 family CD20 PF04103.10 CDI82958.1 - 0.77 9.6 16.5 0.55 10.1 1.7 3.2 3 0 0 3 3 3 0 CD20-like family Activator_LAG-3 PF11498.3 CDI82958.1 - 1.7 7.3 105.8 0.0072 15.1 29.8 3.1 3 0 0 3 3 3 0 Transcriptional activator LAG-3 AIF_C PF14721.1 CDI82958.1 - 3.6 7.8 24.1 4.8 7.4 5.7 3.4 3 0 0 3 3 3 0 Apoptosis-inducing factor, mitochondrion-associated, C-term PRP1_N PF06424.7 CDI82958.1 - 4.7 7.5 21.9 3.7 7.8 0.4 3.2 3 0 0 3 3 3 0 PRP1 splicing factor, N-terminal DUF1764 PF08576.5 CDI82958.1 - 5.5 7.8 33.1 6.8 7.5 8.9 3.3 3 0 0 3 3 3 0 Eukaryotic protein of unknown function (DUF1764) DUF1510 PF07423.6 CDI82958.1 - 5.9 6.1 29.5 3.2 7.0 7.8 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1510) CRAL_TRIO PF00650.15 CDI82960.1 - 0.00013 21.4 0.0 0.00019 20.9 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain EphA2_TM PF14575.1 CDI82962.1 - 0.0057 17.0 3.2 0.094 13.1 0.2 2.3 2 0 0 2 2 2 1 Ephrin type-A receptor 2 transmembrane domain DUF4414 PF14377.1 CDI82962.1 - 0.011 15.6 0.5 0.011 15.6 0.3 3.1 2 1 0 2 2 1 0 Domain of unknown function (DUF4414) Trp_oprn_chp PF09534.5 CDI82962.1 - 0.087 12.4 7.7 0.07 12.7 4.7 1.3 1 1 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) eIF-3_zeta PF05091.7 CDI82962.1 - 0.32 9.5 15.2 0.36 9.3 10.5 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) CD20 PF04103.10 CDI82962.1 - 0.35 10.8 6.9 0.05 13.5 0.9 1.9 1 1 1 2 2 2 0 CD20-like family UPF0542 PF15086.1 CDI82962.1 - 0.42 10.3 0.0 0.42 10.3 0.0 3.3 3 1 0 3 3 2 0 Uncharacterised protein family UPF0542 Presenilin PF01080.12 CDI82962.1 - 0.57 8.9 8.8 0.63 8.7 6.1 1.1 1 0 0 1 1 1 0 Presenilin DUF3357 PF11837.3 CDI82962.1 - 1.3 8.9 5.9 2 8.3 1.3 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3357) Neur_chan_memb PF02932.11 CDI82962.1 - 1.5 8.6 9.9 2 8.2 6.8 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Herpes_UL87 PF03043.9 CDI82962.1 - 1.9 6.7 9.0 1.9 6.7 6.2 1.1 1 0 0 1 1 1 0 Herpesvirus UL87 family DUF4483 PF14825.1 CDI82962.1 - 2.7 7.5 17.7 1.1 8.9 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4483) Hid1 PF12722.2 CDI82962.1 - 3.1 5.3 14.1 3.6 5.1 9.8 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein PH_4 PF15404.1 CDI82962.1 - 3.4 7.1 10.4 3.6 7.0 3.7 2.1 2 0 0 2 2 2 0 Pleckstrin homology domain FLO_LFY PF01698.11 CDI82962.1 - 3.7 6.2 12.6 4.4 6.0 8.7 1.2 1 0 0 1 1 1 0 Floricaula / Leafy protein DUF1800 PF08811.6 CDI82962.1 - 4.7 6.0 20.1 5.8 5.7 14.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1800) FCP1_C PF09309.5 CDI82962.1 - 6.5 5.9 22.0 7.9 5.6 0.6 2.2 2 0 0 2 2 2 0 FCP1, C-terminal MDFI PF15316.1 CDI82962.1 - 7.7 6.4 10.2 9.7 6.1 7.1 1.3 1 0 0 1 1 1 0 MyoD family inhibitor FHIPEP PF00771.15 CDI82962.1 - 8.2 4.6 16.9 17 3.6 11.7 1.5 1 1 0 1 1 1 0 FHIPEP family SAE2 PF08573.5 CDI82962.1 - 8.4 7.1 9.5 6.1 7.6 3.4 2.2 2 0 0 2 2 2 0 DNA repair protein endonuclease SAE2/CtIP C-terminus TMEM154 PF15102.1 CDI82962.1 - 9.7 5.8 12.9 65 3.2 9.0 1.9 1 1 1 2 2 2 0 TMEM154 protein family Activator_LAG-3 PF11498.3 CDI82965.1 - 0.0053 15.5 3.6 0.0053 15.5 2.5 6.5 3 2 3 6 6 6 2 Transcriptional activator LAG-3 Vps39_1 PF10366.4 CDI82975.1 - 0.27 11.2 6.4 0.92 9.5 4.5 1.9 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 1 GNT-I PF03071.10 CDI82975.1 - 3.2 6.2 6.8 5.2 5.5 4.7 1.2 1 0 0 1 1 1 0 GNT-I family FAM60A PF15396.1 CDI82976.1 - 3.4 7.3 24.6 1.4 8.5 0.0 3.4 3 0 0 3 3 3 0 Protein Family FAM60A SpoIIIAH PF12685.2 CDI82977.1 - 0.0002 20.9 15.7 0.0002 20.9 10.9 2.2 1 1 1 2 2 2 1 SpoIIIAH-like protein PBP1_TM PF14812.1 CDI82977.1 - 0.0052 17.0 11.9 0.045 14.0 0.1 2.3 2 0 0 2 2 2 1 Transmembrane domain of transglycosylase PBP1 at N-terminal Med15 PF09606.5 CDI82977.1 - 0.16 10.1 119.9 0.31 9.2 83.1 1.4 1 1 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Suc_Fer-like PF06999.7 CDI82977.1 - 2.4 8.1 13.4 8.4 6.3 5.8 2.2 2 0 0 2 2 2 0 Sucrase/ferredoxin-like PCEMA1 PF07418.6 CDI82977.1 - 6.6 6.0 13.4 12 5.1 9.3 1.4 1 0 0 1 1 1 0 Acidic phosphoprotein precursor PCEMA1 Corona_nucleoca PF00937.13 CDI82984.1 - 0.28 10.1 17.7 0.34 9.8 12.3 1.1 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein CAF-1_p150 PF11600.3 CDI82984.1 - 0.47 9.7 13.8 0.54 9.6 9.6 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal CDC45 PF02724.9 CDI82984.1 - 0.63 7.9 9.7 0.74 7.7 6.7 1.1 1 0 0 1 1 1 0 CDC45-like protein Methyltransf_22 PF13383.1 CDI82984.1 - 3.8 6.9 7.5 2.4 7.6 1.0 2.0 1 1 1 2 2 2 0 Methyltransferase domain SR-25 PF10500.4 CDI82984.1 - 6.5 6.1 20.8 13 5.1 14.4 1.5 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF3446 PF11928.3 CDI82984.1 - 7.1 6.9 10.1 0.64 10.2 2.5 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3446) HisKA_3 PF07730.8 CDI82986.1 - 0.0061 16.8 0.1 0.0061 16.8 0.0 2.6 1 1 2 3 3 3 1 Histidine kinase Suf PF05843.9 CDI82986.1 - 0.012 15.4 13.1 0.017 14.8 9.1 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) zf-ZPR1 PF03367.8 CDI82986.1 - 0.27 10.4 7.9 0.39 9.8 5.5 1.2 1 0 0 1 1 1 0 ZPR1 zinc-finger domain Glt_symporter PF03616.9 CDI82986.1 - 0.66 8.3 2.2 1.1 7.6 1.5 1.3 1 0 0 1 1 1 0 Sodium/glutamate symporter FAM60A PF15396.1 CDI82986.1 - 0.69 9.6 9.8 0.82 9.3 6.8 1.1 1 0 0 1 1 1 0 Protein Family FAM60A G-alpha PF00503.15 CDI82986.1 - 0.85 8.2 9.0 1.1 7.8 6.2 1.2 1 0 0 1 1 1 0 G-protein alpha subunit Herpes_UL25 PF01499.11 CDI82986.1 - 2.1 6.5 16.9 2.4 6.3 11.7 1.0 1 0 0 1 1 1 0 Herpesvirus UL25 family DUF2828 PF11443.3 CDI82986.1 - 2.6 6.1 11.5 4.1 5.4 8.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF2828) Neur_chan_memb PF02932.11 CDI82986.1 - 4.1 7.2 8.9 6.1 6.6 6.2 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region SPX PF03105.14 CDI82986.1 - 4.8 6.8 13.7 5.8 6.6 9.5 1.1 1 0 0 1 1 1 0 SPX domain HlyD_2 PF12700.2 CDI82986.1 - 5.8 5.9 13.6 6.9 5.7 9.4 1.1 1 0 0 1 1 1 0 HlyD family secretion protein eIF-3_zeta PF05091.7 CDI82986.1 - 6 5.3 17.5 7.2 5.0 12.1 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) GNT-I PF03071.10 CDI82986.1 - 7.9 4.8 9.4 5.5 5.4 5.6 1.4 1 1 0 1 1 1 0 GNT-I family DUF2722 PF10846.3 CDI82986.1 - 9.1 5.1 21.5 21 4.0 15.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2722) DUF1675 PF07897.6 CDI82986.1 - 9.2 6.0 11.2 11 5.7 7.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) DUF4411 PF14367.1 CDI82986.1 - 9.3 5.9 12.4 12 5.6 8.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4411) Shadoo PF14999.1 CDI82988.1 - 0.043 13.6 4.3 0.053 13.3 2.9 1.2 1 0 0 1 1 1 0 Shadow of prion protein, neuroprotective Trp_oprn_chp PF09534.5 CDI82988.1 - 0.11 12.0 18.6 0.13 11.8 12.9 1.1 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF3357 PF11837.3 CDI82988.1 - 0.22 11.4 8.3 0.78 9.6 4.9 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF3357) DUF4366 PF14283.1 CDI82988.1 - 0.58 9.5 14.2 0.87 8.9 9.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) DUF2910 PF11139.3 CDI82988.1 - 0.65 9.0 7.3 0.81 8.7 5.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2910) DUF1510 PF07423.6 CDI82988.1 - 0.81 9.0 25.8 1 8.6 17.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DUF4647 PF15504.1 CDI82988.1 - 3.5 6.3 29.6 4.1 6.1 20.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4647) SRRM_C PF15230.1 CDI82988.1 - 4 7.5 11.9 0.26 11.3 1.2 2.1 2 0 0 2 2 2 0 Serine/arginine repetitive matrix protein C-terminus DUF3367 PF11847.3 CDI82988.1 - 4.4 5.1 12.1 5.1 4.9 8.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3367) Herpes_DNAp_acc PF04929.7 CDI82988.1 - 4.8 6.0 20.6 5.6 5.8 14.2 1.0 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Neur_chan_memb PF02932.11 CDI82988.1 - 4.9 6.9 17.7 5.8 6.7 12.3 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF1183 PF06682.7 CDI82988.1 - 5 6.6 13.1 6.6 6.2 9.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) Herpes_PAP PF03325.8 CDI82988.1 - 5.5 6.4 11.7 6.2 6.2 8.1 1.0 1 0 0 1 1 1 0 Herpesvirus polymerase accessory protein DUF4569 PF15133.1 CDI82988.1 - 7.8 5.7 22.7 9.5 5.5 15.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4569) FAM60A PF15396.1 CDI82988.1 - 8.6 6.0 19.9 11 5.7 13.8 1.1 1 0 0 1 1 1 0 Protein Family FAM60A TFIIF_beta PF02270.10 CDI82988.1 - 9.3 5.9 23.0 12 5.6 15.9 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, beta subunit HGTP_anticodon2 PF12745.2 CDI82991.1 - 0.0075 15.4 2.7 0.0083 15.2 1.9 1.0 1 0 0 1 1 1 1 Anticodon binding domain of tRNAs PsbQ PF05757.6 CDI82991.1 - 0.018 14.4 4.9 0.021 14.2 3.4 1.1 1 0 0 1 1 1 0 Oxygen evolving enhancer protein 3 (PsbQ) Spt20 PF12090.3 CDI82991.1 - 0.027 13.8 3.0 0.026 13.8 2.1 1.1 1 0 0 1 1 1 0 Spt20 family CDK2AP PF09806.4 CDI82991.1 - 0.039 14.1 17.0 0.056 13.6 11.8 1.3 1 1 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein CDK5_activator PF03261.10 CDI82991.1 - 0.074 12.3 9.1 0.088 12.1 6.3 1.0 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein Fer4_14 PF13394.1 CDI82991.1 - 0.082 12.9 0.1 0.093 12.7 0.1 1.2 1 0 0 1 1 1 0 4Fe-4S single cluster domain CHASE2 PF05226.6 CDI82991.1 - 0.089 12.0 4.2 0.1 11.8 2.9 1.0 1 0 0 1 1 1 0 CHASE2 domain Suf PF05843.9 CDI82991.1 - 0.17 11.6 5.0 0.14 11.8 3.5 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) WES_acyltransf PF03007.11 CDI82991.1 - 0.17 11.3 5.8 0.2 11.1 4.0 1.0 1 0 0 1 1 1 0 Wax ester synthase-like Acyl-CoA acyltransferase domain Ribosomal_60s PF00428.14 CDI82991.1 - 0.34 11.3 10.0 0.58 10.5 6.9 1.3 1 0 0 1 1 1 0 60s Acidic ribosomal protein PsaN PF05479.6 CDI82991.1 - 0.69 9.8 8.7 1.4 8.9 6.0 1.6 1 1 0 1 1 1 0 Photosystem I reaction centre subunit N (PSAN or PSI-N) LCD1 PF09798.4 CDI82991.1 - 0.84 7.5 7.5 0.87 7.5 5.2 1.0 1 0 0 1 1 1 0 DNA damage checkpoint protein Peptidase_S21 PF00716.12 CDI82991.1 - 1.8 7.7 8.2 2.1 7.5 5.7 1.1 1 0 0 1 1 1 0 Assemblin (Peptidase family S21) FimP PF09766.4 CDI82991.1 - 4.3 6.2 11.5 5.4 5.9 8.0 1.1 1 0 0 1 1 1 0 Fms-interacting protein SelP_N PF04592.9 CDI82991.1 - 4.9 6.4 10.4 6.3 6.1 7.2 1.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Macoilin PF09726.4 CDI82991.1 - 5 5.2 8.4 5.4 5.1 5.8 1.0 1 0 0 1 1 1 0 Transmembrane protein DivIC PF04977.10 CDI82991.1 - 6.5 6.3 9.6 10 5.6 6.7 1.3 1 0 0 1 1 1 0 Septum formation initiator CTP_transf_1 PF01148.15 CDI83000.1 - 5.5 6.5 0.0 8.5 5.9 0.0 1.1 1 0 0 1 1 1 0 Cytidylyltransferase family Ctr PF04145.10 CDI83014.1 - 0.008 16.2 1.2 0.0096 15.9 0.8 1.1 1 0 0 1 1 1 1 Ctr copper transporter family TMEM51 PF15345.1 CDI83014.1 - 0.01 15.5 5.3 0.012 15.3 3.7 1.0 1 0 0 1 1 1 0 Transmembrane protein 51 FHIPEP PF00771.15 CDI83014.1 - 0.011 14.0 2.0 0.012 14.0 1.4 1.0 1 0 0 1 1 1 0 FHIPEP family CobT PF06213.7 CDI83014.1 - 0.011 14.8 7.6 0.013 14.6 5.2 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Dala_Dala_lig_N PF01820.16 CDI83014.1 - 0.012 15.9 3.2 0.016 15.5 2.2 1.1 1 0 0 1 1 1 0 D-ala D-ala ligase N-terminus Serinc PF03348.10 CDI83014.1 - 0.013 14.2 2.8 0.014 14.1 2.0 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) DUF2413 PF10310.4 CDI83014.1 - 0.019 13.8 7.4 0.02 13.7 5.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) Protocadherin PF08374.6 CDI83014.1 - 0.027 14.1 3.0 0.03 13.9 2.1 1.1 1 0 0 1 1 1 0 Protocadherin CD20 PF04103.10 CDI83014.1 - 0.041 13.8 0.0 0.051 13.4 0.0 1.1 1 0 0 1 1 1 0 CD20-like family Shisa PF13908.1 CDI83014.1 - 0.042 14.0 1.0 0.045 13.9 0.7 1.1 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator DUF4392 PF14336.1 CDI83014.1 - 0.046 12.5 3.2 0.055 12.2 2.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4392) GBP_C PF02841.9 CDI83014.1 - 0.048 12.8 10.0 0.054 12.6 6.9 1.1 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain Spt20 PF12090.3 CDI83014.1 - 0.058 12.7 3.4 0.058 12.7 2.4 1.1 1 0 0 1 1 1 0 Spt20 family DUF2217 PF10265.4 CDI83014.1 - 0.065 11.9 4.8 0.072 11.8 3.3 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) Med15 PF09606.5 CDI83014.1 - 0.066 11.4 20.0 0.073 11.2 13.9 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal R_equi_Vir PF05526.6 CDI83014.1 - 0.13 11.9 6.1 0.15 11.6 4.2 1.1 1 0 0 1 1 1 0 Rhodococcus equi virulence-associated protein Folate_carrier PF01770.13 CDI83014.1 - 0.15 10.4 0.9 0.18 10.3 0.6 1.0 1 0 0 1 1 1 0 Reduced folate carrier FimP PF09766.4 CDI83014.1 - 0.19 10.7 8.9 0.22 10.5 6.2 1.1 1 0 0 1 1 1 0 Fms-interacting protein DUF3357 PF11837.3 CDI83014.1 - 0.25 11.2 4.7 2.2 8.1 3.3 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF3357) SHR3_chaperone PF08229.6 CDI83014.1 - 0.25 10.2 8.3 0.28 10.0 5.8 1.1 1 0 0 1 1 1 0 ER membrane protein SH3 OATP PF03137.15 CDI83014.1 - 0.29 9.1 1.2 0.33 8.9 0.8 1.0 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family RAB3GAP2_N PF14655.1 CDI83014.1 - 0.32 9.9 5.9 0.36 9.7 4.1 1.1 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus MelC1 PF06236.6 CDI83014.1 - 0.34 10.8 6.6 0.47 10.4 4.6 1.3 1 0 0 1 1 1 0 Tyrosinase co-factor MelC1 AIF_C PF14721.1 CDI83014.1 - 0.49 10.6 4.8 0.58 10.3 3.3 1.1 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term K_channel_TID PF07941.6 CDI83014.1 - 0.72 10.1 19.1 5.7e+03 -2.4 13.3 2.3 1 1 0 1 1 0 0 Potassium channel Kv1.4 tandem inactivation domain EphA2_TM PF14575.1 CDI83014.1 - 0.86 10.0 6.5 2.2 8.7 4.5 1.7 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain ATAD4 PF15321.1 CDI83014.1 - 1 10.4 8.8 1.4 9.9 6.1 1.2 1 0 0 1 1 1 0 ATPase family AAA domain containing 4 Suf PF05843.9 CDI83014.1 - 1 9.0 6.9 1.1 8.9 4.8 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF3676 PF12429.3 CDI83014.1 - 1.1 8.8 11.0 1.3 8.5 7.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3676) MDFI PF15316.1 CDI83014.1 - 1.2 9.1 3.8 1.4 8.8 2.6 1.1 1 0 0 1 1 1 0 MyoD family inhibitor IncA PF04156.9 CDI83014.1 - 2.5 7.6 16.4 4.1 6.9 11.4 1.4 1 1 0 1 1 1 0 IncA protein DUF4557 PF15101.1 CDI83014.1 - 2.5 7.8 10.0 2.8 7.7 6.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) DUF4259 PF14078.1 CDI83014.1 - 3.3 8.2 9.3 7.3 7.0 6.4 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4259) Claudin_2 PF13903.1 CDI83014.1 - 3.8 7.1 7.3 1.3 8.7 0.1 2.0 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction RskA PF10099.4 CDI83014.1 - 3.9 7.1 17.7 7.4 6.2 12.3 1.4 1 1 0 1 1 1 0 Anti-sigma-K factor rskA DUF4355 PF14265.1 CDI83014.1 - 5.7 6.9 18.1 8 6.4 12.5 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4355) Borrelia_orfA PF02414.10 CDI83015.1 - 3.4 6.7 17.7 5.4 6.0 12.3 1.3 1 0 0 1 1 1 0 Borrelia ORF-A YCII PF03795.9 CDI83022.1 - 0.16 12.2 3.8 0.17 12.1 2.7 1.2 1 0 0 1 1 1 0 YCII-related domain BASP1 PF05466.7 CDI83022.1 - 0.58 9.9 29.4 0.68 9.7 20.4 1.1 1 0 0 1 1 1 0 Brain acid soluble protein 1 (BASP1 protein) DREPP PF05558.7 CDI83022.1 - 6.6 6.5 15.8 8.6 6.1 10.9 1.2 1 0 0 1 1 1 0 DREPP plasma membrane polypeptide Herpes_capsid PF06112.6 CDI83022.1 - 9.8 6.2 9.1 12 5.8 6.3 1.2 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein DUF743 PF05332.6 CDI83023.1 - 0.061 13.2 0.2 0.79 9.7 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF743) DUF2584 PF10763.4 CDI83023.1 - 0.13 12.1 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2584) DUF3025 PF11227.3 CDI83024.1 - 0.067 12.6 1.1 21 4.5 0.0 2.9 2 1 0 3 3 3 0 Protein of unknown function (DUF3025) APC_CDC26 PF10471.4 CDI83024.1 - 2 9.1 7.8 5.8 7.7 5.4 1.8 1 0 0 1 1 1 0 Anaphase-promoting complex APC subunit 1 Apt1 PF10351.4 CDI83027.1 - 0.21 10.3 5.0 0.26 10.0 3.5 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain AFT PF08731.6 CDI83027.1 - 1.5 9.0 5.4 8.1 6.6 0.4 2.2 2 0 0 2 2 2 0 Transcription factor AFT DUF1117 PF06547.7 CDI83027.1 - 3.2 7.8 5.9 6.4 6.9 4.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1117) P5-ATPase PF12409.3 CDI83027.1 - 4.9 7.0 8.0 9.8 6.0 1.2 2.1 2 0 0 2 2 2 0 P5-type ATPase cation transporter CDC45 PF02724.9 CDI83027.1 - 6.9 4.5 17.1 0.35 8.8 0.5 2.6 3 0 0 3 3 3 0 CDC45-like protein RPEL PF02755.10 CDI83030.1 - 0.0096 15.2 0.8 4.5 6.7 0.0 2.6 2 0 0 2 2 2 2 RPEL repeat SR-25 PF10500.4 CDI83037.1 - 3.5e-05 23.3 24.1 4.4e-05 23.0 16.5 1.3 1 1 0 1 1 1 1 Nuclear RNA-splicing-associated protein UNC-50 PF05216.8 CDI83037.1 - 0.071 12.2 0.1 0.1 11.7 0.0 1.3 1 0 0 1 1 1 0 UNC-50 family Invas_SpaK PF03519.9 CDI83037.1 - 0.32 10.8 3.9 0.81 9.5 2.7 1.7 1 0 0 1 1 1 0 Invasion protein B family ODV-E18 PF10717.4 CDI83037.1 - 1.2 8.5 4.0 3.9 6.9 2.8 1.9 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 Peroxin-13_N PF04088.8 CDI83037.1 - 4.1 7.3 17.6 0.14 12.0 1.2 2.2 2 0 0 2 2 2 0 Peroxin 13, N-terminal region ATP-synt_D PF01813.12 CDI83038.1 - 1.3 8.5 7.3 0.044 13.3 0.9 1.6 2 0 0 2 2 2 0 ATP synthase subunit D Utp14 PF04615.8 CDI83038.1 - 5.7 4.9 30.3 7.1 4.6 21.0 1.1 1 0 0 1 1 1 0 Utp14 protein UCH PF00443.24 CDI83040.1 - 2.9e-13 49.5 0.0 3.5e-13 49.2 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ORC2 PF04084.9 CDI83047.1 - 3e-26 92.0 0.0 1.5e-25 89.7 0.0 1.8 1 1 0 1 1 1 1 Origin recognition complex subunit 2 DUF755 PF05501.6 CDI83047.1 - 0.057 13.4 2.6 0.19 11.7 1.8 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF755) SR-25 PF10500.4 CDI83047.1 - 0.65 9.4 9.4 1.4 8.3 6.5 1.5 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Glyco_transf_15 PF01793.11 CDI83051.1 - 3 6.7 10.6 2.7 6.8 1.5 2.2 2 0 0 2 2 2 0 Glycolipid 2-alpha-mannosyltransferase DUF3068 PF11271.3 CDI83051.1 - 5.2 6.0 9.2 0.92 8.5 2.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3068) Glyco_transf_8 PF01501.15 CDI83051.1 - 5.3 6.2 8.4 0.52 9.6 2.0 1.9 1 1 1 2 2 2 0 Glycosyl transferase family 8 CAF-1_p150 PF11600.3 CDI83052.1 - 0.00041 19.7 15.9 0.00041 19.7 11.0 2.6 2 1 0 2 2 2 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal Activator_LAG-3 PF11498.3 CDI83052.1 - 0.003 16.3 19.9 0.003 16.3 13.8 3.0 2 1 0 2 2 2 1 Transcriptional activator LAG-3 Spore_coat_CotO PF14153.1 CDI83052.1 - 0.015 14.7 32.1 0.27 10.6 9.5 2.7 2 0 0 2 2 2 0 Spore coat protein CotO SPX PF03105.14 CDI83052.1 - 0.02 14.7 20.3 0.099 12.4 7.3 2.4 2 0 0 2 2 2 0 SPX domain CDC45 PF02724.9 CDI83052.1 - 1.4 6.8 26.7 0.2 9.6 8.6 2.4 2 0 0 2 2 2 0 CDC45-like protein SPX PF03105.14 CDI83060.1 - 6.5e-05 22.8 4.4 6.5e-05 22.8 3.1 1.1 1 0 0 1 1 1 1 SPX domain Spore_coat_CotO PF14153.1 CDI83060.1 - 0.00027 20.4 13.4 0.0003 20.2 9.3 1.2 1 0 0 1 1 1 1 Spore coat protein CotO SAPS PF04499.10 CDI83060.1 - 0.00046 18.9 3.8 0.00046 18.9 2.7 1.1 1 0 0 1 1 1 1 SIT4 phosphatase-associated protein ODV-E18 PF10717.4 CDI83060.1 - 0.00067 19.0 0.5 0.002 17.5 0.4 1.8 1 0 0 1 1 1 1 Occlusion-derived virus envelope protein ODV-E18 LMBR1 PF04791.11 CDI83060.1 - 0.001 17.7 0.0 0.0019 16.8 0.0 1.3 1 1 0 1 1 1 1 LMBR1-like membrane protein DUF4045 PF13254.1 CDI83060.1 - 0.014 14.6 8.5 0.016 14.5 5.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Neur_chan_memb PF02932.11 CDI83060.1 - 0.043 13.6 10.4 0.0094 15.8 5.2 1.5 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region LmjF365940-deam PF14421.1 CDI83060.1 - 0.044 13.1 0.9 0.061 12.6 0.6 1.4 1 0 0 1 1 1 0 A distinct subfamily of CDD/CDA-like deaminases TMEM154 PF15102.1 CDI83060.1 - 0.14 11.8 0.0 0.14 11.8 0.0 3.3 2 1 1 3 3 2 0 TMEM154 protein family DUF912 PF06024.7 CDI83060.1 - 0.34 10.9 0.0 0.34 10.9 0.0 3.2 2 1 1 3 3 3 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Mem_trans PF03547.13 CDI83060.1 - 0.55 8.4 8.4 2.7 6.1 0.0 2.2 2 0 0 2 2 2 0 Membrane transport protein RIC3 PF15361.1 CDI83060.1 - 0.71 10.0 21.2 12 6.0 0.0 2.5 2 0 0 2 2 2 0 Resistance to inhibitors of cholinesterase homologue 3 Band_3_cyto PF07565.8 CDI83060.1 - 0.77 9.2 15.6 0.22 10.9 9.1 1.4 2 0 0 2 2 1 0 Band 3 cytoplasmic domain eIF3_subunit PF08597.5 CDI83060.1 - 0.97 8.9 18.0 1.4 8.4 12.5 1.4 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit SAGA-Tad1 PF12767.2 CDI83060.1 - 1.1 8.8 18.7 1.7 8.2 13.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit DUF3827 PF12877.2 CDI83060.1 - 1.2 7.1 15.3 1.5 6.7 10.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) DUF1510 PF07423.6 CDI83060.1 - 1.2 8.4 25.8 3 7.1 17.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) AUX_IAA PF02309.11 CDI83060.1 - 1.4 8.5 11.8 2 8.1 8.2 1.3 1 0 0 1 1 1 0 AUX/IAA family Protocadherin PF08374.6 CDI83060.1 - 1.5 8.4 11.1 2.5 7.6 7.7 1.4 1 0 0 1 1 1 0 Protocadherin DUF2828 PF11443.3 CDI83060.1 - 1.6 6.8 9.9 1.9 6.6 6.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) CDC45 PF02724.9 CDI83060.1 - 2.1 6.3 19.2 0.092 10.7 9.1 1.6 2 0 0 2 2 2 0 CDC45-like protein BTV_NS2 PF04514.7 CDI83060.1 - 2.1 7.1 13.9 2.5 6.9 9.6 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 AvrE PF11725.3 CDI83060.1 - 2.3 5.1 19.4 2.7 4.8 13.4 1.1 1 0 0 1 1 1 0 Pathogenicity factor GAGA_bind PF06217.7 CDI83060.1 - 3.1 7.6 17.5 4.4 7.1 12.1 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family DUF4220 PF13968.1 CDI83060.1 - 3.6 6.5 8.5 11 4.9 5.4 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4220) NPR3 PF03666.8 CDI83060.1 - 4.6 5.6 16.4 6.1 5.2 11.3 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Tfb4 PF03850.9 CDI83060.1 - 5 6.3 9.6 7.8 5.6 6.7 1.3 1 0 0 1 1 1 0 Transcription factor Tfb4 Baculo_PP31 PF05311.6 CDI83060.1 - 6.3 5.9 20.1 9.5 5.3 14.0 1.2 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) FAM60A PF15396.1 CDI83060.1 - 6.7 6.3 13.7 9.5 5.9 9.5 1.2 1 0 0 1 1 1 0 Protein Family FAM60A CRT10 PF08728.5 CDI83060.1 - 6.8 4.5 10.2 7.5 4.3 7.1 1.0 1 0 0 1 1 1 0 CRT10 Kei1 PF08552.6 CDI83060.1 - 8.5 5.9 15.9 13 5.3 0.1 2.2 2 0 0 2 2 2 0 Inositolphosphorylceramide synthase subunit Kei1 MMR1 PF08505.5 CDI83060.1 - 9 6.2 20.0 14 5.6 13.9 1.5 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein Raftlin PF15250.1 CDI83060.1 - 9.2 4.6 18.0 13 4.2 12.5 1.1 1 0 0 1 1 1 0 Raftlin Herpes_DNAp_acc PF04929.7 CDI83060.1 - 9.7 5.0 14.3 13 4.6 9.9 1.2 1 0 0 1 1 1 0 Herpes DNA replication accessory factor XRN_N PF03159.13 CDI83061.1 - 1.4e-34 119.5 6.7 9.1e-34 116.8 0.6 5.4 2 1 2 5 5 5 2 XRN 5'-3' exonuclease N-terminus Mucin PF01456.12 CDI83061.1 - 0.0059 16.3 1.0 0.0059 16.3 0.7 4.2 4 2 2 6 6 6 1 Mucin-like glycoprotein Ribosomal_60s PF00428.14 CDI83061.1 - 0.0066 16.8 6.9 0.0066 16.8 4.8 4.0 4 0 0 4 4 4 2 60s Acidic ribosomal protein Shadoo PF14999.1 CDI83061.1 - 0.18 11.6 26.5 1.5 8.7 0.2 3.5 3 0 0 3 3 3 0 Shadow of prion protein, neuroprotective DUF21 PF01595.15 CDI83061.1 - 0.24 10.6 2.1 1.7 7.8 0.1 2.7 2 0 0 2 2 2 0 Domain of unknown function DUF21 Peroxin-13_N PF04088.8 CDI83063.1 - 0.014 15.3 0.2 0.016 15.2 0.1 1.1 1 0 0 1 1 1 0 Peroxin 13, N-terminal region Spt20 PF12090.3 CDI83063.1 - 0.05 12.9 6.8 0.054 12.8 4.7 1.1 1 0 0 1 1 1 0 Spt20 family PEX11 PF05648.9 CDI83063.1 - 0.057 12.6 0.3 0.056 12.7 0.2 1.0 1 0 0 1 1 1 0 Peroxisomal biogenesis factor 11 (PEX11) Agouti PF05039.7 CDI83063.1 - 0.071 13.4 1.5 0.08 13.2 1.0 1.1 1 0 0 1 1 1 0 Agouti protein DivIC PF04977.10 CDI83063.1 - 0.085 12.3 4.5 0.087 12.3 3.1 1.1 1 0 0 1 1 1 0 Septum formation initiator DUF1840 PF08895.6 CDI83063.1 - 0.094 12.7 2.1 0.11 12.5 1.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1840) DUF3700 PF12481.3 CDI83063.1 - 0.1 11.8 1.7 0.12 11.5 1.2 1.0 1 0 0 1 1 1 0 Aluminium induced protein FimP PF09766.4 CDI83063.1 - 0.11 11.5 6.9 0.11 11.5 4.8 1.0 1 0 0 1 1 1 0 Fms-interacting protein PCYCGC PF13798.1 CDI83063.1 - 0.12 12.1 0.8 0.13 11.9 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function with PCYCGC motif DUF2489 PF10675.4 CDI83063.1 - 0.17 11.5 7.5 0.2 11.3 5.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2489) Suf PF05843.9 CDI83063.1 - 0.17 11.5 7.8 0.19 11.4 5.4 1.0 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF4557 PF15101.1 CDI83063.1 - 0.34 10.7 6.4 0.32 10.8 4.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) PAT1 PF09770.4 CDI83063.1 - 0.35 9.0 13.9 0.35 9.0 9.7 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 FCP1_C PF09309.5 CDI83063.1 - 0.36 10.1 4.1 0.34 10.1 2.8 1.1 1 0 0 1 1 1 0 FCP1, C-terminal Spc7_N PF15402.1 CDI83063.1 - 0.39 8.6 5.8 0.42 8.5 4.0 1.0 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 APC_CDC26 PF10471.4 CDI83063.1 - 0.65 10.7 12.5 0.91 10.3 8.7 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex APC subunit 1 FAM222A PF15258.1 CDI83063.1 - 0.82 8.8 11.7 0.8 8.8 8.1 1.1 1 0 0 1 1 1 0 Protein family of FAM222A RAB3GAP2_N PF14655.1 CDI83063.1 - 0.88 8.5 5.5 0.92 8.4 3.8 1.1 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Med15 PF09606.5 CDI83063.1 - 0.97 7.5 19.1 0.96 7.5 13.2 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF788 PF05620.6 CDI83063.1 - 1.1 9.1 4.1 1.3 8.8 2.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF788) Pex14_N PF04695.8 CDI83063.1 - 1.4 8.9 8.2 1.5 8.8 5.7 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region UPF0560 PF10577.4 CDI83063.1 - 1.5 6.9 8.4 1.5 7.0 5.9 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 ERF PF04404.7 CDI83063.1 - 2.3 7.7 10.2 3 7.3 7.1 1.1 1 0 0 1 1 1 0 ERF superfamily BAF1_ABF1 PF04684.8 CDI83063.1 - 2.3 6.9 20.9 2.4 6.9 14.5 1.0 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Pex26 PF07163.7 CDI83063.1 - 2.5 6.9 5.9 2.7 6.8 4.1 1.0 1 0 0 1 1 1 0 Pex26 protein Activator_LAG-3 PF11498.3 CDI83063.1 - 2.9 6.5 24.3 3 6.5 16.8 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 DUF4175 PF13779.1 CDI83063.1 - 4.4 4.8 17.2 4.7 4.7 11.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) DUF2802 PF10975.3 CDI83063.1 - 8.7 6.1 13.4 11 5.9 9.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2802) MMR_HSR1 PF01926.18 CDI83091.1 - 8.2e-15 54.7 0.0 2.7e-14 53.1 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 CDI83091.1 - 0.0018 17.5 0.0 0.0028 16.9 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.18 CDI83091.1 - 0.017 14.9 0.0 0.12 12.1 0.1 2.3 2 0 0 2 2 2 0 Dynamin family GTP_EFTU PF00009.22 CDI83091.1 - 0.029 13.8 0.0 10 5.4 0.0 2.6 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain DUF258 PF03193.11 CDI83091.1 - 0.08 12.1 0.0 0.15 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 BAF1_ABF1 PF04684.8 CDI83096.1 - 0.00012 21.1 22.5 0.00014 20.9 15.6 1.1 1 0 0 1 1 1 1 BAF1 / ABF1 chromatin reorganising factor TFIIF_beta PF02270.10 CDI83096.1 - 0.018 14.8 5.2 0.018 14.8 3.6 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, beta subunit Gly-zipper_OmpA PF13436.1 CDI83096.1 - 0.023 14.3 10.3 0.033 13.8 7.1 1.2 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain AAA_28 PF13521.1 CDI83096.1 - 0.027 14.4 3.3 0.033 14.1 2.3 1.1 1 0 0 1 1 1 0 AAA domain Gti1_Pac2 PF09729.4 CDI83096.1 - 0.032 14.1 1.8 0.039 13.8 1.3 1.1 1 0 0 1 1 1 0 Gti1/Pac2 family CDK2AP PF09806.4 CDI83096.1 - 0.058 13.6 14.4 0.07 13.3 10.0 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein PAT1 PF09770.4 CDI83096.1 - 0.063 11.5 15.2 0.063 11.5 10.5 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF4175 PF13779.1 CDI83096.1 - 0.068 10.8 18.7 0.077 10.6 12.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) SpoIIIAH PF12685.2 CDI83096.1 - 0.082 12.3 8.9 0.084 12.3 6.2 1.0 1 0 0 1 1 1 0 SpoIIIAH-like protein vMSA PF00695.14 CDI83096.1 - 0.091 11.9 2.1 0.1 11.7 1.5 1.0 1 0 0 1 1 1 0 Major surface antigen from hepadnavirus Chorion_2 PF03964.10 CDI83096.1 - 0.1 13.1 7.5 0.15 12.6 5.2 1.3 1 0 0 1 1 1 0 Chorion family 2 DUF2201_N PF13203.1 CDI83096.1 - 0.13 11.4 10.5 0.13 11.4 7.2 1.0 1 0 0 1 1 1 0 Putative metallopeptidase domain SLD3 PF08639.5 CDI83096.1 - 0.14 10.7 6.7 0.14 10.7 4.6 1.1 1 0 0 1 1 1 0 DNA replication regulator SLD3 Pex16 PF08610.5 CDI83096.1 - 0.15 11.0 2.0 0.14 11.1 1.4 1.1 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) Peptidase_S49_N PF08496.5 CDI83096.1 - 0.17 11.6 5.2 0.2 11.4 3.6 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal CDK5_activator PF03261.10 CDI83096.1 - 0.18 11.1 6.9 0.19 11.0 4.8 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein Spore_coat_CotO PF14153.1 CDI83096.1 - 0.18 11.2 11.7 0.21 11.0 8.1 1.1 1 0 0 1 1 1 0 Spore coat protein CotO Med15 PF09606.5 CDI83096.1 - 0.18 9.9 26.5 0.19 9.8 18.4 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal WES_acyltransf PF03007.11 CDI83096.1 - 0.2 11.1 5.8 0.23 10.9 4.0 1.0 1 0 0 1 1 1 0 Wax ester synthase-like Acyl-CoA acyltransferase domain DUF3138 PF11336.3 CDI83096.1 - 0.27 9.3 15.7 0.28 9.2 10.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) DUF3347 PF11827.3 CDI83096.1 - 0.3 11.0 11.1 0.36 10.8 7.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3347) FAM176 PF14851.1 CDI83096.1 - 0.3 10.7 2.3 0.34 10.5 1.6 1.2 1 0 0 1 1 1 0 FAM176 family Spt20 PF12090.3 CDI83096.1 - 0.9 8.8 12.0 1.2 8.3 8.3 1.2 1 0 0 1 1 1 0 Spt20 family FAM60A PF15396.1 CDI83096.1 - 1.1 8.9 5.0 1.3 8.7 3.5 1.1 1 0 0 1 1 1 0 Protein Family FAM60A Tfb4 PF03850.9 CDI83096.1 - 1.2 8.3 5.5 1.2 8.3 3.8 1.0 1 0 0 1 1 1 0 Transcription factor Tfb4 FimP PF09766.4 CDI83096.1 - 1.3 8.0 15.3 1.6 7.6 10.6 1.1 1 0 0 1 1 1 0 Fms-interacting protein Suf PF05843.9 CDI83096.1 - 1.3 8.6 10.4 1.5 8.4 7.2 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Hid1 PF12722.2 CDI83096.1 - 1.8 6.1 6.5 1.8 6.1 4.5 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DREPP PF05558.7 CDI83096.1 - 1.8 8.3 8.2 2.3 8.0 5.7 1.1 1 0 0 1 1 1 0 DREPP plasma membrane polypeptide PAXIP1_C PF15364.1 CDI83096.1 - 1.9 8.3 10.6 2.7 7.9 7.4 1.2 1 0 0 1 1 1 0 PAXIP1-associated-protein-1 C term PTIP binding protein DivIC PF04977.10 CDI83096.1 - 2.2 7.8 13.1 3.5 7.1 9.1 1.3 1 0 0 1 1 1 0 Septum formation initiator Ycf1 PF05758.7 CDI83096.1 - 2.4 5.7 6.6 2.5 5.6 4.6 1.0 1 0 0 1 1 1 0 Ycf1 UPF0560 PF10577.4 CDI83096.1 - 2.5 6.2 11.2 2.8 6.1 7.7 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Robl_LC7 PF03259.12 CDI83096.1 - 2.8 7.5 7.2 4.7 6.8 5.0 1.4 1 1 0 1 1 1 0 Roadblock/LC7 domain SpaB_C PF14028.1 CDI83096.1 - 3.2 7.2 11.5 3.5 7.1 8.0 1.0 1 0 0 1 1 1 0 SpaB C-terminal domain Serinc PF03348.10 CDI83096.1 - 5.9 5.4 5.8 6 5.4 4.0 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) Nitroreductase PF00881.19 CDI83096.1 - 9.2 6.0 9.6 11 5.7 6.7 1.1 1 0 0 1 1 1 0 Nitroreductase family Nop53 PF07767.6 CDI83103.1 - 0.074 12.0 12.9 0.12 11.3 9.0 1.3 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Sec62 PF03839.11 CDI83103.1 - 1.1 8.6 6.5 1.6 8.1 4.5 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 DUF1764 PF08576.5 CDI83103.1 - 2.7 8.8 11.5 2.8 8.7 7.0 1.7 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF1764) Lin-8 PF03353.10 CDI83103.1 - 6.2 6.0 16.5 0.97 8.6 8.7 1.5 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist RAP1 PF07218.6 CDI83103.1 - 9.5 4.1 8.6 12 3.8 6.0 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) PAT1 PF09770.4 CDI83104.1 - 0.31 9.2 89.1 0.49 8.5 61.8 1.5 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 PLRV_ORF5 PF01690.12 CDI83114.1 - 0.33 10.0 41.2 0.37 9.8 28.6 1.0 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein AF-4 PF05110.8 CDI83114.1 - 0.55 8.0 45.2 0.62 7.8 31.4 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein TFIIA PF03153.8 CDI83114.1 - 4.7 7.0 61.3 5.9 6.6 42.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit MIP-T3 PF10243.4 CDI83114.1 - 4.9 5.5 52.9 5.5 5.3 36.7 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Suf PF05843.9 CDI83116.1 - 0.02 14.6 6.5 0.023 14.4 4.5 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF3464 PF11947.3 CDI83116.1 - 0.11 11.9 3.9 0.19 11.1 2.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) RRN9 PF10680.4 CDI83116.1 - 0.2 11.3 1.6 0.35 10.6 0.5 2.0 2 0 0 2 2 2 0 RNA polymerase I specific transcription initiation factor Indigoidine_A PF04227.7 CDI83116.1 - 0.25 10.5 1.1 0.36 10.0 0.8 1.3 1 0 0 1 1 1 0 Indigoidine synthase A like protein Exonuc_VII_L PF02601.10 CDI83116.1 - 0.51 9.4 11.5 0.61 9.2 8.0 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit AAA_23 PF13476.1 CDI83116.1 - 0.69 10.2 15.9 1 9.6 11.0 1.4 1 0 0 1 1 1 0 AAA domain PRP1_N PF06424.7 CDI83116.1 - 0.93 9.8 8.5 1.3 9.3 0.9 2.5 2 0 0 2 2 2 0 PRP1 splicing factor, N-terminal Cob_adeno_trans PF01923.13 CDI83116.1 - 1.6 8.4 8.9 0.32 10.7 1.1 2.2 1 1 1 2 2 2 0 Cobalamin adenosyltransferase V_ATPase_I PF01496.14 CDI83116.1 - 1.7 6.3 9.3 1.8 6.2 6.5 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Peptidase_S46 PF10459.4 CDI83116.1 - 3.9 5.7 10.6 4.3 5.6 7.4 1.2 1 0 0 1 1 1 0 Peptidase S46 DUF4228 PF14009.1 CDI83116.1 - 4.5 7.3 10.1 6.7 6.8 6.9 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4228) Peptidase_S49_N PF08496.5 CDI83116.1 - 6.9 6.4 15.2 23 4.7 9.0 2.2 1 1 0 2 2 2 0 Peptidase family S49 N-terminal DUF1635 PF07795.6 CDI83129.1 - 0.016 14.5 4.0 0.018 14.4 2.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) Secretin_N_2 PF07655.8 CDI83129.1 - 0.088 13.2 15.2 0.12 12.7 10.6 1.2 1 0 0 1 1 1 0 Secretin N-terminal domain SecG PF03840.9 CDI83129.1 - 0.095 12.4 6.6 0.21 11.3 2.1 2.1 2 0 0 2 2 2 0 Preprotein translocase SecG subunit Pap_E4 PF02711.9 CDI83129.1 - 0.12 13.1 2.2 0.17 12.7 1.5 1.2 1 0 0 1 1 1 0 E4 protein Plasmodium_Vir PF05795.6 CDI83129.1 - 0.16 11.1 5.1 0.17 11.0 3.5 1.0 1 0 0 1 1 1 0 Plasmodium vivax Vir protein DUF2071 PF09844.4 CDI83129.1 - 0.19 11.1 2.0 0.21 10.9 1.4 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (COG2071) Pex16 PF08610.5 CDI83129.1 - 0.22 10.4 3.2 0.24 10.3 2.2 1.0 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) Apc1 PF12859.2 CDI83129.1 - 0.22 11.7 2.9 0.28 11.4 2.0 1.2 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 1 SR-25 PF10500.4 CDI83129.1 - 0.32 10.4 25.0 0.38 10.2 17.3 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Calc_CGRP_IAPP PF00214.14 CDI83129.1 - 0.4 10.7 6.5 0.46 10.5 4.5 1.2 1 0 0 1 1 1 0 Calcitonin / CGRP / IAPP family Ctr PF04145.10 CDI83129.1 - 0.44 10.5 3.4 0.53 10.3 2.3 1.1 1 0 0 1 1 1 0 Ctr copper transporter family DUF4367 PF14285.1 CDI83129.1 - 0.81 8.9 5.2 0.25 10.6 2.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4367) FAM60A PF15396.1 CDI83129.1 - 0.9 9.2 6.3 0.97 9.1 4.4 1.1 1 0 0 1 1 1 0 Protein Family FAM60A DUF3824 PF12868.2 CDI83129.1 - 1.1 10.2 17.1 1.7 9.5 11.9 1.5 1 1 0 1 1 1 0 Domain of unknwon function (DUF3824) PA26 PF04636.8 CDI83129.1 - 1.4 7.4 5.7 1.5 7.4 4.0 1.0 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) DUF4557 PF15101.1 CDI83129.1 - 2.2 8.0 7.8 2.6 7.8 5.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) DUF1183 PF06682.7 CDI83129.1 - 2.4 7.6 7.9 2.5 7.6 5.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) DUF515 PF04415.7 CDI83129.1 - 2.6 6.1 9.7 3.1 5.9 6.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) DUF572 PF04502.8 CDI83129.1 - 3 6.9 9.2 3.2 6.8 6.4 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF966 PF06136.8 CDI83129.1 - 3 7.1 11.4 3.1 7.1 7.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Ribosomal_60s PF00428.14 CDI83129.1 - 3.1 8.2 30.6 1.5 9.3 5.7 2.2 2 0 0 2 2 2 0 60s Acidic ribosomal protein Presenilin PF01080.12 CDI83129.1 - 4.1 6.1 10.9 4.6 5.9 7.6 1.0 1 0 0 1 1 1 0 Presenilin PAP1 PF08601.5 CDI83129.1 - 4.7 6.7 14.6 5 6.7 10.1 1.0 1 0 0 1 1 1 0 Transcription factor PAP1 Prenyltrans_2 PF13249.1 CDI83129.1 - 5.1 7.5 14.0 18 5.7 9.7 1.9 1 1 0 1 1 1 0 Prenyltransferase-like APC_CDC26 PF10471.4 CDI83129.1 - 5.3 7.8 15.5 1.7 9.4 8.5 1.7 1 1 1 2 2 2 0 Anaphase-promoting complex APC subunit 1 Mcm10 PF09332.6 CDI83129.1 - 6.3 6.0 13.9 6.6 5.9 9.7 1.0 1 0 0 1 1 1 0 Mcm10 replication factor SOBP PF15279.1 CDI83129.1 - 6.4 7.0 9.8 6.7 6.9 6.8 1.0 1 0 0 1 1 1 0 Sine oculis-binding protein Macoilin PF09726.4 CDI83129.1 - 6.8 4.8 17.3 7 4.7 12.0 1.1 1 0 0 1 1 1 0 Transmembrane protein DUF2217 PF10265.4 CDI83129.1 - 6.9 5.3 12.2 7.1 5.2 8.5 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) RAP1 PF07218.6 CDI83129.1 - 7.6 4.4 17.4 8.3 4.3 12.0 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) MRP-S31 PF15433.1 CDI83129.1 - 9.1 5.6 8.8 10 5.4 6.1 1.1 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 Pkinase PF00069.20 CDI83131.1 - 5.8e-50 169.8 0.0 1.4e-49 168.6 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDI83131.1 - 3.1e-34 118.2 0.0 4.5e-34 117.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CDI83131.1 - 4.6e-08 32.3 0.0 7.6e-08 31.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like RRM_1 PF00076.17 CDI83132.1 - 9.2e-30 102.0 0.0 5.1e-18 64.4 0.0 2.1 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CDI83132.1 - 2.8e-20 72.0 0.0 4.7e-12 45.7 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CDI83132.1 - 2.4e-08 33.6 0.0 3.5e-06 26.7 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2730 PF10805.3 CDI83134.1 - 0.013 15.2 3.2 0.013 15.2 2.2 3.3 2 2 1 3 3 3 0 Protein of unknown function (DUF2730) SIR2 PF02146.12 CDI83134.1 - 0.071 12.8 3.4 0.057 13.1 1.1 1.8 2 0 0 2 2 2 0 Sir2 family NPV_P10 PF05531.7 CDI83134.1 - 0.12 12.5 6.7 5.1 7.4 0.4 3.5 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Reo_sigmaC PF04582.7 CDI83134.1 - 0.13 11.4 1.3 1.5 7.9 0.1 2.3 2 0 0 2 2 2 0 Reovirus sigma C capsid protein Bacillus_HBL PF05791.6 CDI83134.1 - 0.16 11.3 13.5 0.026 13.9 2.8 3.2 2 2 1 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) AAA_13 PF13166.1 CDI83134.1 - 1.3 7.3 25.9 0.93 7.8 1.1 3.0 1 1 2 3 3 3 0 AAA domain DUF883 PF05957.8 CDI83137.1 - 2.8 8.3 8.3 46 4.4 4.5 2.9 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) RRM_1 PF00076.17 CDI83138.1 - 4.9e-34 115.7 0.1 2.1e-16 59.3 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CDI83138.1 - 4.3e-27 93.8 0.1 1.6e-12 47.2 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CDI83138.1 - 1.5e-11 43.9 0.0 6.9e-05 22.6 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OB_RNB PF08206.6 CDI83138.1 - 0.006 16.0 0.1 0.15 11.6 0.0 2.3 2 0 0 2 2 2 1 Ribonuclease B OB domain BAF1_ABF1 PF04684.8 CDI83138.1 - 0.17 10.7 3.1 0.36 9.6 2.2 1.6 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Stimulus_sens_1 PF13756.1 CDI83139.1 - 0.029 14.7 0.2 1 9.7 0.1 2.9 2 0 0 2 2 2 0 Stimulus-sensing domain TFIIF_beta PF02270.10 CDI83140.1 - 0.003 17.4 18.0 0.0035 17.2 12.4 1.1 1 0 0 1 1 1 1 Transcription initiation factor IIF, beta subunit RNA_pol_3_Rpc31 PF11705.3 CDI83140.1 - 0.015 15.2 6.4 0.017 15.0 4.5 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Activator_LAG-3 PF11498.3 CDI83140.1 - 0.021 13.5 48.9 0.023 13.4 33.9 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 AAA_23 PF13476.1 CDI83140.1 - 0.21 11.9 17.3 0.25 11.6 12.0 1.1 1 0 0 1 1 1 0 AAA domain MRP-S26 PF14943.1 CDI83140.1 - 0.59 9.6 14.2 0.79 9.2 9.8 1.3 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 CEP44 PF15007.1 CDI83153.1 - 9.1e-32 109.5 0.3 3.4e-31 107.6 0.0 2.2 2 1 0 2 2 2 1 Centrosomal spindle body, CEP44 1-cysPrx_C PF10417.4 CDI83158.1 - 2.7e-12 46.1 0.0 5.1e-12 45.2 0.0 1.5 2 0 0 2 2 2 1 C-terminal domain of 1-Cys peroxiredoxin Tho2 PF11262.3 CDI83161.1 - 0.043 12.8 6.9 0.058 12.4 4.8 1.1 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 AP2 PF00847.15 CDI83161.1 - 0.059 13.5 0.2 0.059 13.5 0.2 5.1 7 0 0 7 7 7 0 AP2 domain SAGA-Tad1 PF12767.2 CDI83161.1 - 0.13 11.8 13.9 0.2 11.2 9.6 1.5 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit SAPS PF04499.10 CDI83161.1 - 0.23 10.0 7.3 0.24 9.9 5.0 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Hid1 PF12722.2 CDI83161.1 - 1.2 6.7 15.8 1.4 6.4 10.9 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Ycf1 PF05758.7 CDI83161.1 - 1.4 6.5 11.1 1.7 6.2 7.7 1.1 1 0 0 1 1 1 0 Ycf1 FAM60A PF15396.1 CDI83161.1 - 2.2 7.9 12.5 3.8 7.1 8.7 1.5 1 0 0 1 1 1 0 Protein Family FAM60A PPP4R2 PF09184.6 CDI83161.1 - 3 7.3 11.7 4.3 6.8 8.1 1.2 1 0 0 1 1 1 0 PPP4R2 PA26 PF04636.8 CDI83161.1 - 5.7 5.5 10.3 8 5.0 7.1 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) RNA_pol_Rpb4 PF03874.11 CDI83179.1 - 0.00025 21.0 0.0 0.00054 19.9 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb4 WD40 PF00400.27 CDI83180.1 - 0.13 12.1 5.3 31 4.6 0.0 5.2 5 1 0 5 5 5 0 WD domain, G-beta repeat SlyX PF04102.7 CDI83181.1 - 0.034 14.5 7.8 0.52 10.7 0.0 4.2 3 1 1 4 4 4 0 SlyX DUF2205 PF10224.4 CDI83181.1 - 0.051 13.1 5.9 0.36 10.4 0.8 2.6 2 0 0 2 2 2 0 Predicted coiled-coil protein (DUF2205) IncA PF04156.9 CDI83181.1 - 0.23 11.0 19.4 0.15 11.6 2.3 3.3 3 0 0 3 3 3 0 IncA protein Metallophos PF00149.23 CDI83182.1 - 6.3e-11 42.0 0.0 8.7e-11 41.5 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 CDI83182.1 - 0.011 15.6 0.0 0.015 15.1 0.0 1.3 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain PhoD PF09423.5 CDI83182.1 - 0.059 11.9 0.0 0.076 11.5 0.0 1.1 1 0 0 1 1 1 0 PhoD-like phosphatase Mre11_DNA_bind PF04152.9 CDI83183.1 - 9.5e-28 97.2 6.6 4.7e-21 75.4 0.0 3.5 4 1 0 4 4 4 2 Mre11 DNA-binding presumed domain DUF3306 PF11748.3 CDI83183.1 - 0.066 13.8 4.6 0.18 12.4 3.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3306) DUF3369 PF11849.3 CDI83183.1 - 0.17 11.8 5.7 0.35 10.8 4.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3369) Androgen_recep PF02166.11 CDI83183.1 - 0.37 9.6 11.8 0.56 9.0 8.2 1.2 1 0 0 1 1 1 0 Androgen receptor PAT1 PF09770.4 CDI83183.1 - 0.4 8.8 14.8 0.52 8.4 10.2 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 NAM-associated PF14303.1 CDI83185.1 - 0.0058 16.9 19.5 0.0058 16.9 13.5 1.7 2 0 0 2 2 2 1 No apical meristem-associated C-terminal domain AAA_23 PF13476.1 CDI83185.1 - 0.037 14.3 15.5 0.043 14.1 10.7 1.1 1 0 0 1 1 1 0 AAA domain RR_TM4-6 PF06459.7 CDI83185.1 - 2.3 8.0 14.5 3.3 7.5 10.0 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CAF-1_p150 PF11600.3 CDI83187.1 - 0.63 9.3 53.6 0.79 9.0 37.2 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal PAT1 PF09770.4 CDI83187.1 - 1.2 7.3 58.5 1.2 7.2 40.5 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SprA-related PF12118.3 CDI83187.1 - 2.6 7.2 71.3 3.1 7.0 49.4 1.1 1 0 0 1 1 1 0 SprA-related family Dsh_C PF12316.3 CDI83187.1 - 8.1 6.4 29.2 11 6.1 20.3 1.2 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal FYDLN_acid PF09538.5 CDI83191.1 - 4 8.0 15.1 4.7 7.8 10.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) DUF1510 PF07423.6 CDI83191.1 - 6.2 6.1 27.6 6.5 6.0 19.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Condensation PF00668.15 CDI83200.1 - 0.02 13.7 5.6 0.046 12.5 3.9 1.5 1 0 0 1 1 1 0 Condensation domain Proteasome_A_N PF10584.4 CDI83212.1 - 1e-08 34.3 0.0 1.6e-08 33.6 0.0 1.3 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Draxin PF15550.1 CDI83212.1 - 0.0019 17.9 8.7 0.0023 17.6 6.0 1.0 1 0 0 1 1 1 1 Draxin DDRGK PF09756.4 CDI83212.1 - 0.016 14.6 14.0 0.017 14.5 9.7 1.1 1 0 0 1 1 1 0 DDRGK domain DUF913 PF06025.7 CDI83212.1 - 0.02 13.6 9.1 0.025 13.3 6.3 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) SpoIIIAH PF12685.2 CDI83212.1 - 0.02 14.3 12.3 0.025 14.0 8.5 1.0 1 0 0 1 1 1 0 SpoIIIAH-like protein MAT1 PF06391.8 CDI83212.1 - 0.021 14.4 14.1 0.025 14.1 9.8 1.1 1 0 0 1 1 1 0 CDK-activating kinase assembly factor MAT1 Bud13 PF09736.4 CDI83212.1 - 0.049 13.8 15.8 0.061 13.5 11.0 1.2 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex DUF572 PF04502.8 CDI83212.1 - 0.059 12.5 13.8 0.076 12.2 9.6 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) CDC73 PF05179.9 CDI83212.1 - 0.075 12.3 10.7 0.089 12.1 7.4 1.0 1 0 0 1 1 1 0 RNA pol II accessory factor, Cdc73 family Cwf_Cwc_15 PF04889.7 CDI83212.1 - 0.15 11.7 17.5 0.21 11.2 12.2 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein NARP1 PF12569.3 CDI83212.1 - 0.16 10.6 10.3 0.17 10.5 7.2 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Peptidase_U57 PF05582.7 CDI83212.1 - 0.2 10.6 10.4 0.24 10.3 7.2 1.1 1 0 0 1 1 1 0 YabG peptidase U57 Peptidase_S49_N PF08496.5 CDI83212.1 - 0.22 11.3 9.3 0.25 11.1 6.4 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal FCP1_C PF09309.5 CDI83212.1 - 0.22 10.7 25.6 0.43 9.8 17.8 1.4 1 1 0 1 1 1 0 FCP1, C-terminal Plasmodium_Vir PF05795.6 CDI83212.1 - 0.25 10.4 9.0 0.32 10.1 6.3 1.0 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Dicty_REP PF05086.7 CDI83212.1 - 0.28 8.9 12.1 0.31 8.7 8.4 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein eIF-3_zeta PF05091.7 CDI83212.1 - 0.28 9.7 17.5 0.31 9.6 12.1 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF4175 PF13779.1 CDI83212.1 - 0.34 8.5 42.9 0.38 8.3 29.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Ycf1 PF05758.7 CDI83212.1 - 0.45 8.1 12.9 0.48 8.0 8.9 1.0 1 0 0 1 1 1 0 Ycf1 RED_N PF07808.8 CDI83212.1 - 0.56 9.3 22.5 0.7 9.0 15.6 1.2 1 0 0 1 1 1 0 RED-like protein N-terminal region Otopetrin PF03189.8 CDI83212.1 - 0.68 8.8 6.3 0.76 8.7 4.4 1.1 1 0 0 1 1 1 0 Otopetrin SAPS PF04499.10 CDI83212.1 - 0.82 8.2 14.2 0.96 8.0 9.9 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Peroxin-13_N PF04088.8 CDI83212.1 - 0.97 9.3 8.2 0.43 10.5 3.8 1.7 2 0 0 2 2 2 0 Peroxin 13, N-terminal region SAGA-Tad1 PF12767.2 CDI83212.1 - 1 8.9 20.1 1.5 8.4 13.9 1.2 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit Neur_chan_memb PF02932.11 CDI83212.1 - 1.2 8.9 12.1 1.6 8.5 8.4 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Cellulose_synt PF03552.9 CDI83212.1 - 1.3 7.2 6.8 1.3 7.2 4.7 1.1 1 0 0 1 1 1 0 Cellulose synthase Sec62 PF03839.11 CDI83212.1 - 1.3 8.3 6.6 1.4 8.2 4.6 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 FimP PF09766.4 CDI83212.1 - 1.4 7.9 29.5 2.3 7.2 20.4 1.3 1 0 0 1 1 1 0 Fms-interacting protein DUF3260 PF11658.3 CDI83212.1 - 1.4 6.9 9.9 1.4 6.9 6.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3260) Adeno_VII PF03228.9 CDI83212.1 - 1.6 9.3 9.1 2.4 8.7 6.3 1.3 1 0 0 1 1 1 0 Adenoviral core protein VII Peptidase_S15 PF02129.13 CDI83212.1 - 1.6 8.1 10.7 1.7 7.9 7.4 1.1 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) PA26 PF04636.8 CDI83212.1 - 1.6 7.3 10.7 1.8 7.1 7.4 1.0 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) BNR_3 PF13859.1 CDI83212.1 - 1.6 7.7 7.3 1.9 7.4 5.0 1.1 1 0 0 1 1 1 0 BNR repeat-like domain FHIPEP PF00771.15 CDI83212.1 - 1.7 6.8 9.3 1.9 6.7 6.4 1.1 1 0 0 1 1 1 0 FHIPEP family DUF1800 PF08811.6 CDI83212.1 - 2 7.2 16.9 2.1 7.1 11.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1800) Dehalogenase PF13486.1 CDI83212.1 - 2.4 7.5 8.2 2.8 7.3 5.7 1.1 1 0 0 1 1 1 0 Reductive dehalogenase subunit OmpH PF03938.9 CDI83212.1 - 2.5 8.0 32.7 3 7.7 22.6 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF853 PF05872.7 CDI83212.1 - 3.1 6.0 12.1 3.5 5.8 8.4 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) SpoVR PF04293.8 CDI83212.1 - 3.4 5.9 13.4 4.1 5.6 9.3 1.1 1 0 0 1 1 1 0 SpoVR like protein DUF2126 PF09899.4 CDI83212.1 - 3.5 5.5 10.7 4 5.3 7.4 1.0 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) VIT1 PF01988.14 CDI83212.1 - 3.8 6.9 4.8 4.3 6.7 3.3 1.1 1 0 0 1 1 1 0 VIT family DUF4355 PF14265.1 CDI83212.1 - 3.8 7.4 22.2 5.2 7.0 15.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4355) G0-G1_switch_2 PF15103.1 CDI83212.1 - 4.8 7.4 11.7 9.8 6.4 8.1 1.5 1 0 0 1 1 1 0 G0/G1 switch protein 2 DUF4647 PF15504.1 CDI83212.1 - 5 5.8 22.2 5.8 5.6 15.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4647) GBP_C PF02841.9 CDI83212.1 - 5.1 6.1 26.4 6.3 5.8 18.3 1.0 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain Endonuc_Holl PF10107.4 CDI83212.1 - 5.7 6.6 15.3 8 6.1 10.6 1.2 1 0 0 1 1 1 0 Endonuclease related to archaeal Holliday junction resolvase Polyoma_coat2 PF00761.15 CDI83212.1 - 6.6 6.1 13.5 7.8 5.8 9.4 1.1 1 0 0 1 1 1 0 Polyomavirus coat protein DUF106 PF01956.11 CDI83212.1 - 6.7 6.2 11.4 7.3 6.0 7.9 1.2 1 0 0 1 1 1 0 Integral membrane protein DUF106 DUF2217 PF10265.4 CDI83212.1 - 6.9 5.3 15.6 8.9 4.9 10.8 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) tRNA-synt_2c PF01411.14 CDI83212.1 - 7.8 4.6 10.8 9.2 4.4 7.5 1.0 1 0 0 1 1 1 0 tRNA synthetases class II (A) DUF3373 PF11853.3 CDI83212.1 - 8.3 4.8 14.9 9.3 4.6 10.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) FUSC PF04632.7 CDI83212.1 - 8.6 4.6 6.9 9.3 4.5 4.8 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF912 PF06024.7 CDI83212.1 - 9.1 6.3 11.7 16 5.6 7.0 2.0 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Paramyxo_ncap PF00973.14 CDI83212.1 - 9.5 4.7 15.0 11 4.6 10.4 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein CBM_14 PF01607.19 CDI83221.1 - 0.014 15.2 0.1 0.029 14.2 0.0 1.4 1 0 0 1 1 1 0 Chitin binding Peritrophin-A domain MRP-S31 PF15433.1 CDI83221.1 - 0.42 9.9 26.3 0.15 11.4 4.1 2.1 2 0 0 2 2 2 0 Mitochondrial 28S ribosomal protein S31 Med15 PF09606.5 CDI83221.1 - 1.2 7.1 71.5 1.8 6.6 49.6 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Kei1 PF08552.6 CDI83221.1 - 2.5 7.6 11.3 3.6 7.2 2.4 2.3 2 0 0 2 2 2 0 Inositolphosphorylceramide synthase subunit Kei1 CDC27 PF09507.5 CDI83221.1 - 5.3 6.1 29.7 7.3 5.6 20.6 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 eIF-3_zeta PF05091.7 CDI83221.1 - 5.6 5.4 21.6 4.3 5.8 2.6 2.1 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF4366 PF14283.1 CDI83221.1 - 6.3 6.1 13.6 0.044 13.2 1.9 2.6 2 2 1 3 3 3 0 Domain of unknown function (DUF4366) DUF515 PF04415.7 CDI83224.1 - 6.2 4.9 10.7 9.5 4.3 7.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF515) CAF-1_p150 PF11600.3 CDI83227.1 - 0.0014 18.0 13.9 0.0014 18.0 9.6 2.1 2 0 0 2 2 2 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal YajC PF02699.10 CDI83227.1 - 0.041 13.5 0.3 0.13 11.9 0.2 1.8 1 0 0 1 1 1 0 Preprotein translocase subunit DREPP PF05558.7 CDI83227.1 - 0.092 12.5 2.1 0.18 11.6 1.4 1.5 1 0 0 1 1 1 0 DREPP plasma membrane polypeptide Trypan_PARP PF05887.6 CDI83227.1 - 3.8 7.3 7.7 7.7 6.3 5.3 1.5 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DUF940 PF06082.6 CDI83232.1 - 1.6 7.1 4.3 1.7 7.0 3.0 1.0 1 0 0 1 1 1 0 Bacterial putative lipoprotein (DUF940) DSBA PF01323.15 CDI83232.1 - 3.4 7.1 9.9 3.9 6.9 6.9 1.1 1 0 0 1 1 1 0 DSBA-like thioredoxin domain FimP PF09766.4 CDI83238.1 - 0.0015 17.6 23.5 0.0017 17.5 16.3 1.0 1 0 0 1 1 1 1 Fms-interacting protein Kei1 PF08552.6 CDI83238.1 - 0.0026 17.4 5.6 0.0028 17.3 3.9 1.0 1 0 0 1 1 1 1 Inositolphosphorylceramide synthase subunit Kei1 DUF4337 PF14235.1 CDI83238.1 - 0.013 15.3 9.4 0.014 15.2 6.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) PBP1_TM PF14812.1 CDI83238.1 - 0.016 15.4 2.4 0.018 15.3 1.6 1.1 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Glyco_transf_15 PF01793.11 CDI83238.1 - 0.026 13.4 9.9 0.026 13.4 6.9 1.0 1 0 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase DUF912 PF06024.7 CDI83238.1 - 0.036 14.1 7.4 0.056 13.5 5.1 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Tim54 PF11711.3 CDI83238.1 - 0.046 12.3 5.2 0.046 12.3 3.6 1.0 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Folate_carrier PF01770.13 CDI83238.1 - 0.071 11.6 11.5 0.078 11.4 8.0 1.0 1 0 0 1 1 1 0 Reduced folate carrier DUF4557 PF15101.1 CDI83238.1 - 0.089 12.6 25.5 0.092 12.5 17.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) Ctr PF04145.10 CDI83238.1 - 0.11 12.5 8.6 0.13 12.3 6.0 1.1 1 0 0 1 1 1 0 Ctr copper transporter family DUF2126 PF09899.4 CDI83238.1 - 0.14 10.1 10.6 0.15 10.0 7.3 1.0 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) Suf PF05843.9 CDI83238.1 - 0.14 11.8 20.2 0.2 11.3 14.0 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DXP_synthase_N PF13292.1 CDI83238.1 - 0.15 11.0 3.0 0.15 10.9 2.1 1.0 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase Nucleoside_tran PF01733.13 CDI83238.1 - 0.15 11.1 6.4 0.15 11.1 4.4 1.0 1 0 0 1 1 1 0 Nucleoside transporter Peptidase_S49_N PF08496.5 CDI83238.1 - 0.16 11.7 13.3 0.18 11.5 9.2 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal SeqA PF03925.8 CDI83238.1 - 0.21 11.2 12.0 0.22 11.2 8.3 1.0 1 0 0 1 1 1 0 SeqA protein DUF3464 PF11947.3 CDI83238.1 - 0.24 10.8 10.4 0.25 10.7 7.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) AAA_11 PF13086.1 CDI83238.1 - 0.28 10.7 16.8 0.33 10.4 11.6 1.0 1 0 0 1 1 1 0 AAA domain TMEM51 PF15345.1 CDI83238.1 - 0.31 10.7 14.6 0.31 10.7 10.2 1.2 1 0 0 1 1 1 0 Transmembrane protein 51 G-alpha PF00503.15 CDI83238.1 - 0.34 9.5 12.5 0.33 9.5 8.7 1.0 1 0 0 1 1 1 0 G-protein alpha subunit DUF3675 PF12428.3 CDI83238.1 - 0.36 11.1 6.4 0.45 10.7 4.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3675) DUF853 PF05872.7 CDI83238.1 - 0.36 9.1 12.3 0.39 8.9 8.5 1.0 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) Maf1 PF09174.5 CDI83238.1 - 0.39 10.5 9.6 0.45 10.3 6.7 1.0 1 0 0 1 1 1 0 Maf1 regulator Glt_symporter PF03616.9 CDI83238.1 - 0.4 9.1 5.0 0.4 9.1 3.5 1.1 1 0 0 1 1 1 0 Sodium/glutamate symporter DUF106 PF01956.11 CDI83238.1 - 0.41 10.1 14.5 0.43 10.0 10.1 1.1 1 0 0 1 1 1 0 Integral membrane protein DUF106 Peroxin-13_N PF04088.8 CDI83238.1 - 0.42 10.5 7.5 0.5 10.3 5.2 1.1 1 0 0 1 1 1 0 Peroxin 13, N-terminal region Raftlin PF15250.1 CDI83238.1 - 0.44 9.0 13.7 0.49 8.8 9.5 1.0 1 0 0 1 1 1 0 Raftlin DUF3306 PF11748.3 CDI83238.1 - 0.47 11.1 13.6 0.52 10.9 9.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3306) FliP PF00813.15 CDI83238.1 - 0.52 9.9 8.7 0.58 9.8 6.0 1.0 1 0 0 1 1 1 0 FliP family PAT1 PF09770.4 CDI83238.1 - 0.52 8.4 39.7 0.54 8.4 27.5 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF2347 PF09804.4 CDI83238.1 - 0.66 9.2 8.1 0.72 9.0 5.6 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2347) Pex14_N PF04695.8 CDI83238.1 - 0.72 9.8 25.3 0.86 9.6 17.5 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DDRGK PF09756.4 CDI83238.1 - 0.76 9.1 21.8 0.88 8.9 15.1 1.0 1 0 0 1 1 1 0 DDRGK domain PH_4 PF15404.1 CDI83238.1 - 0.78 9.2 12.4 0.84 9.1 8.6 1.1 1 0 0 1 1 1 0 Pleckstrin homology domain Dala_Dala_lig_N PF01820.16 CDI83238.1 - 0.81 10.0 7.9 1 9.7 5.5 1.1 1 0 0 1 1 1 0 D-ala D-ala ligase N-terminus FAM176 PF14851.1 CDI83238.1 - 0.88 9.2 8.1 1.1 8.9 5.6 1.3 1 0 0 1 1 1 0 FAM176 family ALG3 PF05208.8 CDI83238.1 - 1.1 8.3 7.0 1.2 8.2 4.8 1.0 1 0 0 1 1 1 0 ALG3 protein EIIBC-GUT_N PF03612.9 CDI83238.1 - 1.2 8.7 13.3 1.4 8.5 9.2 1.1 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus FAM60A PF15396.1 CDI83238.1 - 1.3 8.7 12.6 1.6 8.4 8.7 1.1 1 0 0 1 1 1 0 Protein Family FAM60A Dynamin_N PF00350.18 CDI83238.1 - 1.5 8.6 8.4 1.6 8.5 5.8 1.1 1 0 0 1 1 1 0 Dynamin family Plasmodium_Vir PF05795.6 CDI83238.1 - 1.5 7.9 5.8 1.6 7.8 4.1 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Serinc PF03348.10 CDI83238.1 - 1.6 7.3 15.1 1.7 7.2 10.5 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) FHIPEP PF00771.15 CDI83238.1 - 1.6 6.9 10.8 1.6 6.9 7.5 1.1 1 0 0 1 1 1 0 FHIPEP family SpoIIP PF07454.6 CDI83238.1 - 1.6 7.7 11.9 1.7 7.7 8.3 1.0 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) FYDLN_acid PF09538.5 CDI83238.1 - 1.6 9.3 6.4 2 9.0 4.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) Gti1_Pac2 PF09729.4 CDI83238.1 - 1.7 8.5 12.4 1.9 8.3 8.6 1.1 1 0 0 1 1 1 0 Gti1/Pac2 family SpoVR PF04293.8 CDI83238.1 - 1.7 6.9 15.0 1.7 6.9 10.4 1.0 1 0 0 1 1 1 0 SpoVR like protein Zip PF02535.17 CDI83238.1 - 1.7 7.5 5.7 1.7 7.5 4.0 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Auxin_canalis PF05703.6 CDI83238.1 - 1.8 8.2 6.7 2 8.1 4.6 1.1 1 0 0 1 1 1 0 Auxin canalisation Dehalogenase PF13486.1 CDI83238.1 - 2 7.7 8.5 2.2 7.6 5.9 1.0 1 0 0 1 1 1 0 Reductive dehalogenase subunit CRF1 PF10380.4 CDI83238.1 - 2.1 8.6 10.8 2.3 8.5 7.5 1.1 1 0 0 1 1 1 0 Transcription factor CRF1 Pex16 PF08610.5 CDI83238.1 - 2.2 7.2 14.1 2.2 7.1 9.7 1.1 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) SLD3 PF08639.5 CDI83238.1 - 2.3 6.7 18.3 2.3 6.7 12.7 1.0 1 0 0 1 1 1 0 DNA replication regulator SLD3 DUF4220 PF13968.1 CDI83238.1 - 2.4 7.1 10.2 2.7 6.9 7.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4220) DDHD PF02862.12 CDI83238.1 - 2.5 7.8 15.6 2.9 7.6 10.8 1.0 1 0 0 1 1 1 0 DDHD domain SID-1_RNA_chan PF13965.1 CDI83238.1 - 2.5 6.1 8.8 2.6 6.1 6.1 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 RR_TM4-6 PF06459.7 CDI83238.1 - 2.6 7.8 16.7 3 7.6 11.6 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 HCO3_cotransp PF00955.16 CDI83238.1 - 2.8 6.4 5.9 2.8 6.4 4.1 1.0 1 0 0 1 1 1 0 HCO3- transporter family ATAD4 PF15321.1 CDI83238.1 - 3 8.9 15.9 4.2 8.4 11.0 1.2 1 0 0 1 1 1 0 ATPase family AAA domain containing 4 DUF4080 PF13311.1 CDI83238.1 - 3 7.8 8.5 3.1 7.8 5.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4080) SAGA-Tad1 PF12767.2 CDI83238.1 - 3.1 7.3 21.6 3.6 7.1 15.0 1.1 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit Band_3_cyto PF07565.8 CDI83238.1 - 3.2 7.1 18.0 3.6 7.0 12.5 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain DUF1266 PF06889.6 CDI83238.1 - 3.2 7.5 12.3 3.8 7.2 8.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1266) CDC45 PF02724.9 CDI83238.1 - 3.3 5.6 14.2 3.7 5.4 9.9 1.0 1 0 0 1 1 1 0 CDC45-like protein HGTP_anticodon2 PF12745.2 CDI83238.1 - 3.4 6.7 14.8 3.8 6.5 10.2 1.0 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs DUF4045 PF13254.1 CDI83238.1 - 3.9 6.6 13.1 4.2 6.5 9.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) GOLD_2 PF13897.1 CDI83238.1 - 3.9 7.7 6.6 4.4 7.5 4.6 1.1 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking FlaG PF03646.10 CDI83238.1 - 3.9 7.6 24.0 5.2 7.2 16.6 1.2 1 0 0 1 1 1 0 FlaG protein SPX PF03105.14 CDI83238.1 - 4 7.1 14.8 4.4 7.0 10.2 1.0 1 0 0 1 1 1 0 SPX domain DUF2058 PF09831.4 CDI83238.1 - 4.2 7.2 28.8 4.8 7.0 20.0 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2058) AUX_IAA PF02309.11 CDI83238.1 - 4.3 7.0 13.5 4.9 6.8 9.4 1.1 1 0 0 1 1 1 0 AUX/IAA family DUF3474 PF11960.3 CDI83238.1 - 4.4 7.3 5.3 5.8 6.9 3.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3474) Ycf1 PF05758.7 CDI83238.1 - 4.7 4.7 16.6 5.1 4.6 11.5 1.0 1 0 0 1 1 1 0 Ycf1 DUF3512 PF12024.3 CDI83238.1 - 5 6.3 14.3 6.6 5.9 9.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3512) DUF2828 PF11443.3 CDI83238.1 - 5.2 5.1 13.0 5.7 5.0 9.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) DUF2370 PF10176.4 CDI83238.1 - 5.4 6.2 9.0 6.4 6.0 6.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) TFIIA PF03153.8 CDI83238.1 - 5.8 6.6 31.2 6.2 6.6 21.6 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF822 PF05687.8 CDI83238.1 - 6.3 7.1 12.7 7.2 6.9 8.8 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF822) AIF_C PF14721.1 CDI83238.1 - 6.6 6.9 15.1 8.1 6.7 10.5 1.1 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Spore_coat_CotO PF14153.1 CDI83238.1 - 7.5 5.9 26.8 9.4 5.6 18.6 1.1 1 0 0 1 1 1 0 Spore coat protein CotO CPSF100_C PF13299.1 CDI83238.1 - 7.6 6.6 14.8 8.7 6.4 10.3 1.1 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal eIF-3_zeta PF05091.7 CDI83238.1 - 8.2 4.9 24.1 9 4.7 16.7 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Otopetrin PF03189.8 CDI83238.1 - 8.2 5.2 9.1 8.6 5.2 6.3 1.0 1 0 0 1 1 1 0 Otopetrin tRNA-synt_2c PF01411.14 CDI83238.1 - 8.2 4.5 11.0 8.9 4.4 7.6 1.0 1 0 0 1 1 1 0 tRNA synthetases class II (A) Glyco_transf_6 PF03414.8 CDI83238.1 - 8.3 4.7 11.0 8.9 4.6 7.6 1.0 1 0 0 1 1 1 0 Glycosyltransferase family 6 Rtf2 PF04641.7 CDI83238.1 - 8.5 5.4 17.2 10 5.2 12.0 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger RED_N PF07808.8 CDI83238.1 - 9 5.4 26.7 11 5.1 18.5 1.1 1 0 0 1 1 1 0 RED-like protein N-terminal region Paramyxo_ncap PF00973.14 CDI83238.1 - 9.5 4.7 13.5 11 4.6 9.4 1.0 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein DUF1800 PF08811.6 CDI83238.1 - 9.7 4.9 21.1 9.9 4.9 14.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1800) Baculo_PP31 PF05311.6 CDI83238.1 - 9.7 5.3 19.0 11 5.1 13.2 1.0 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) RP-C_C PF11800.3 CDI83238.1 - 9.9 5.7 16.5 11 5.6 11.4 1.0 1 0 0 1 1 1 0 Replication protein C C-terminal region Mem_trans PF03547.13 CDI83238.1 - 10 4.3 7.6 9.9 4.3 5.3 1.1 1 0 0 1 1 1 0 Membrane transport protein IncA PF04156.9 CDI83248.1 - 5.1e-05 22.9 2.2 5.1e-05 22.9 1.5 2.8 2 1 1 3 3 1 1 IncA protein SelP_N PF04592.9 CDI83248.1 - 0.02 14.3 6.8 0.029 13.7 4.7 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Rsm1 PF08600.5 CDI83248.1 - 0.034 13.9 1.4 0.07 12.9 1.0 1.6 1 1 0 1 1 1 0 Rsm1-like Selenoprotein_S PF06936.6 CDI83248.1 - 0.28 10.6 6.8 0.51 9.8 4.7 1.4 1 0 0 1 1 1 0 Selenoprotein S (SelS) TFIIF_alpha PF05793.7 CDI83248.1 - 0.49 8.7 20.6 0.63 8.3 14.3 1.0 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) ELL PF10390.4 CDI83248.1 - 0.58 9.3 10.5 0.7 9.0 7.2 1.2 1 0 0 1 1 1 0 RNA polymerase II elongation factor ELL Plasmodium_Vir PF05795.6 CDI83248.1 - 0.65 9.1 9.6 0.8 8.8 6.6 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein DNA_pol_viral_N PF00242.12 CDI83248.1 - 2.2 7.2 20.5 2.7 6.9 14.2 1.1 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain CCDC84 PF14968.1 CDI83248.1 - 2.8 7.3 13.8 3.4 7.0 9.6 1.1 1 0 0 1 1 1 0 Coiled coil protein 84 DUF572 PF04502.8 CDI83248.1 - 3.5 6.7 20.1 4.6 6.3 13.9 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) SAPS PF04499.10 CDI83248.1 - 4.1 5.9 9.5 4.6 5.7 6.6 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Hid1 PF12722.2 CDI83248.1 - 6.5 4.2 17.1 7.7 4.0 11.9 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Utp14 PF04615.8 CDI83248.1 - 7.3 4.6 18.6 8.5 4.3 12.9 1.0 1 0 0 1 1 1 0 Utp14 protein Sec62 PF03839.11 CDI83265.1 - 6 6.2 18.1 6.9 6.0 12.5 1.0 1 0 0 1 1 1 0 Translocation protein Sec62 SprA-related PF12118.3 CDI83265.1 - 7.6 5.7 36.3 8.4 5.6 25.2 1.1 1 0 0 1 1 1 0 SprA-related family DUF3682 PF12446.3 CDI83265.1 - 8 6.7 35.8 9.6 6.5 24.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) Med15 PF09606.5 CDI83266.1 - 0.45 8.6 48.3 0.51 8.4 33.5 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal IPK PF03770.11 CDI83266.1 - 2.4 7.7 11.6 2.9 7.4 8.0 1.1 1 0 0 1 1 1 0 Inositol polyphosphate kinase FAM176 PF14851.1 CDI83266.1 - 5.3 6.7 8.6 14 5.3 2.9 2.1 2 0 0 2 2 2 0 FAM176 family DUF3357 PF11837.3 CDI83266.1 - 8 6.3 8.0 0.69 9.7 1.2 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF3357) TMEM154 PF15102.1 CDI83266.1 - 8.9 6.0 10.7 12 5.5 7.4 1.4 1 1 0 1 1 1 0 TMEM154 protein family Macoilin PF09726.4 CDI83281.1 - 0.0017 16.7 53.9 0.0023 16.2 37.4 1.2 1 0 0 1 1 1 1 Transmembrane protein Ycf1 PF05758.7 CDI83298.1 - 0.00082 17.2 24.8 0.032 11.9 9.0 2.2 2 0 0 2 2 2 2 Ycf1 TT_ORF1 PF02956.9 CDI83298.1 - 0.002 16.6 14.7 0.002 16.6 10.2 2.7 2 1 1 3 3 3 1 TT viral orf 1 Plasmodium_Vir PF05795.6 CDI83298.1 - 0.069 12.3 6.4 0.37 9.9 0.7 2.4 2 0 0 2 2 2 0 Plasmodium vivax Vir protein SPX PF03105.14 CDI83298.1 - 5 6.8 41.1 0.35 10.6 14.5 2.7 2 2 0 2 2 2 0 SPX domain Peptidase_S8 PF00082.17 CDI83306.1 - 8.5e-13 48.0 0.1 8.9e-13 48.0 0.1 1.0 1 0 0 1 1 1 1 Subtilase family IncA PF04156.9 CDI83318.1 - 0.0027 17.3 7.3 0.0027 17.3 5.0 2.1 2 0 0 2 2 1 1 IncA protein FimP PF09766.4 CDI83318.1 - 0.0042 16.2 16.2 0.0056 15.7 11.2 1.1 1 0 0 1 1 1 1 Fms-interacting protein eIF-3_zeta PF05091.7 CDI83318.1 - 0.054 12.1 14.5 0.066 11.8 10.0 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) XAP5 PF04921.9 CDI83318.1 - 0.058 12.9 10.4 0.087 12.3 7.2 1.2 1 0 0 1 1 1 0 XAP5, circadian clock regulator Serinc PF03348.10 CDI83318.1 - 0.14 10.8 11.5 0.21 10.2 8.0 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) Utp14 PF04615.8 CDI83318.1 - 0.16 10.1 21.9 0.21 9.7 15.2 1.1 1 0 0 1 1 1 0 Utp14 protein CDC45 PF02724.9 CDI83318.1 - 0.24 9.4 13.5 0.3 9.0 9.4 1.1 1 0 0 1 1 1 0 CDC45-like protein Peptidase_S49_N PF08496.5 CDI83318.1 - 0.29 10.9 6.5 0.43 10.3 4.5 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal FLO_LFY PF01698.11 CDI83318.1 - 0.38 9.5 9.0 0.66 8.7 6.2 1.5 1 0 0 1 1 1 0 Floricaula / Leafy protein Draxin PF15550.1 CDI83318.1 - 0.49 10.0 11.8 0.93 9.0 8.2 1.4 1 0 0 1 1 1 0 Draxin Plasmodium_Vir PF05795.6 CDI83318.1 - 0.72 8.9 9.0 0.99 8.5 6.2 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Peptidase_S64 PF08192.6 CDI83318.1 - 0.83 7.9 15.7 1.4 7.2 10.9 1.4 1 0 0 1 1 1 0 Peptidase family S64 Tim54 PF11711.3 CDI83318.1 - 1.7 7.1 10.0 2.9 6.3 7.0 1.5 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Ycf1 PF05758.7 CDI83318.1 - 1.8 6.2 10.7 2.1 5.9 7.4 1.0 1 0 0 1 1 1 0 Ycf1 Band_3_cyto PF07565.8 CDI83318.1 - 1.9 7.9 10.9 2.8 7.3 7.5 1.3 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Paf1 PF03985.8 CDI83318.1 - 2.3 6.8 20.1 3.3 6.3 13.9 1.2 1 0 0 1 1 1 0 Paf1 Paramyxo_ncap PF00973.14 CDI83318.1 - 2.8 6.5 15.9 3.7 6.1 11.0 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein DUF2215 PF10225.4 CDI83318.1 - 3.2 7.1 6.6 4.8 6.5 4.6 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) Lin-8 PF03353.10 CDI83318.1 - 3.4 6.8 17.3 5.6 6.1 12.0 1.4 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Hid1 PF12722.2 CDI83318.1 - 3.4 5.2 20.9 4.5 4.8 14.5 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF1635 PF07795.6 CDI83318.1 - 3.6 6.8 15.8 6.4 6.0 11.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) Miff PF05644.6 CDI83318.1 - 4.4 6.8 16.9 7.5 6.1 11.7 1.3 1 0 0 1 1 1 0 Mitochondrial and peroxisomal fission factor Mff NST1 PF13945.1 CDI83318.1 - 5.8 6.9 27.2 14 5.7 18.8 1.6 1 0 0 1 1 1 0 Salt tolerance down-regulator DNA_pol_viral_N PF00242.12 CDI83318.1 - 8.4 5.3 21.4 12 4.8 14.8 1.2 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain PBP1_TM PF14812.1 CDI83326.1 - 0.63 10.3 27.0 0.054 13.8 5.0 3.2 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Sigma_reg_C PF13791.1 CDI83326.1 - 3.3 7.7 14.1 0.31 11.0 2.9 2.3 2 0 0 2 2 2 0 Sigma factor regulator C-terminal DUF572 PF04502.8 CDI83326.1 - 3.3 6.8 38.3 4.9 6.2 26.5 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) Herpes_UL87 PF03043.9 CDI83326.1 - 4.5 5.5 22.0 6 5.1 15.3 1.1 1 0 0 1 1 1 0 Herpesvirus UL87 family FAM196 PF15265.1 CDI83329.1 - 0.44 9.7 29.3 0.62 9.2 20.3 1.2 1 0 0 1 1 1 0 FAM196 family SPOUT_MTase PF02590.12 CDI83329.1 - 1.8 8.2 7.5 0.69 9.6 3.1 1.9 1 1 1 2 2 2 0 Predicted SPOUT methyltransferase Secretin_N_2 PF07655.8 CDI83329.1 - 7.1 7.0 35.7 6.8 7.1 6.3 3.6 4 0 0 4 4 4 0 Secretin N-terminal domain Utp14 PF04615.8 CDI83329.1 - 8 4.4 28.5 10 4.1 19.7 1.1 1 0 0 1 1 1 0 Utp14 protein CAF-1_p150 PF11600.3 CDI83331.1 - 0.00013 21.3 32.3 0.0002 20.8 22.4 1.2 1 0 0 1 1 1 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal SprA-related PF12118.3 CDI83331.1 - 0.0021 17.4 44.5 0.0027 17.0 30.8 1.0 1 0 0 1 1 1 1 SprA-related family Ycf1 PF05758.7 CDI83331.1 - 0.031 12.0 18.3 0.033 11.9 12.7 1.0 1 0 0 1 1 1 0 Ycf1 SoxE PF06525.6 CDI83331.1 - 0.11 11.7 2.1 0.15 11.3 1.5 1.2 1 0 0 1 1 1 0 Sulfocyanin (SoxE) Raftlin PF15250.1 CDI83331.1 - 0.11 10.9 16.8 0.17 10.3 11.6 1.3 1 0 0 1 1 1 0 Raftlin Nop53 PF07767.6 CDI83331.1 - 0.18 10.7 29.0 0.21 10.5 20.1 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) eIF-3_zeta PF05091.7 CDI83331.1 - 0.18 10.3 22.5 0.19 10.2 15.6 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Med19 PF10278.4 CDI83331.1 - 0.22 11.1 10.9 0.3 10.7 7.6 1.3 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 SID-1_RNA_chan PF13965.1 CDI83331.1 - 0.23 9.6 12.8 0.28 9.3 8.8 1.3 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DUF4175 PF13779.1 CDI83331.1 - 0.26 8.9 46.2 0.29 8.7 32.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Med15 PF09606.5 CDI83331.1 - 0.33 9.1 45.6 0.38 8.9 31.6 1.3 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal PAT1 PF09770.4 CDI83331.1 - 0.79 7.8 35.4 0.78 7.9 24.5 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF3260 PF11658.3 CDI83331.1 - 2.4 6.2 16.5 2.8 5.9 11.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3260) SOBP PF15279.1 CDI83331.1 - 2.8 8.2 25.2 3.6 7.8 17.5 1.0 1 0 0 1 1 1 0 Sine oculis-binding protein DUF2561 PF10812.3 CDI83331.1 - 8.4 5.9 8.5 42 3.6 5.9 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2561) DUF677 PF05055.7 CDI83368.1 - 0.0034 16.1 0.4 0.0034 16.1 0.3 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF677) N6_N4_Mtase PF01555.13 CDI83368.1 - 0.06 12.8 0.0 0.31 10.5 0.0 1.9 1 1 0 1 1 1 0 DNA methylase DUF4045 PF13254.1 CDI83368.1 - 0.2 10.8 21.4 0.26 10.5 14.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Ycf1 PF05758.7 CDI83368.1 - 0.58 7.8 13.6 0.64 7.6 9.4 1.3 1 0 0 1 1 1 0 Ycf1 BTV_NS2 PF04514.7 CDI83368.1 - 1.6 7.5 12.9 2.1 7.1 8.9 1.2 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 DUF45 PF01863.12 CDI83368.1 - 2.2 8.0 15.9 3.6 7.3 11.0 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF45 Cellulose_synt PF03552.9 CDI83368.1 - 6.2 4.9 6.2 8.5 4.5 4.3 1.1 1 0 0 1 1 1 0 Cellulose synthase PAT1 PF09770.4 CDI83376.1 - 0.011 14.0 78.0 0.011 14.0 54.1 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Utp14 PF04615.8 CDI83376.1 - 0.087 10.9 36.0 0.092 10.9 25.0 1.0 1 0 0 1 1 1 0 Utp14 protein DUF4045 PF13254.1 CDI83376.1 - 0.12 11.6 31.8 0.12 11.5 22.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) CENP-T PF15511.1 CDI83376.1 - 0.37 9.9 30.6 0.39 9.9 21.2 1.0 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T GAGA_bind PF06217.7 CDI83376.1 - 0.59 10.0 34.1 0.68 9.8 23.6 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family Totivirus_coat PF05518.6 CDI83376.1 - 0.96 7.1 14.8 1 7.1 10.2 1.0 1 0 0 1 1 1 0 Totivirus coat protein TFIIA PF03153.8 CDI83376.1 - 1 9.1 57.7 1.3 8.7 40.0 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Nha1_C PF08619.5 CDI83376.1 - 1.6 7.9 31.8 1.6 7.9 22.0 1.1 1 0 0 1 1 1 0 Alkali metal cation/H+ antiporter Nha1 C terminus SAPS PF04499.10 CDI83376.1 - 2.5 6.6 28.9 2.8 6.4 20.0 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein PLRV_ORF5 PF01690.12 CDI83376.1 - 2.7 7.0 31.9 2.7 7.0 22.1 1.0 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein CDC45 PF02724.9 CDI83376.1 - 3 5.7 36.9 3.5 5.5 25.6 1.0 1 0 0 1 1 1 0 CDC45-like protein Asp-B-Hydro_N PF05279.6 CDI83376.1 - 3.4 7.4 26.7 3.7 7.3 18.5 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Dicty_REP PF05086.7 CDI83376.1 - 4.6 4.8 24.4 4.9 4.7 16.9 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Hid1 PF12722.2 CDI83376.1 - 4.8 4.7 39.3 5.1 4.6 27.2 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein GPCR_chapero_1 PF11904.3 CDI83376.1 - 6.5 5.7 29.4 7.2 5.6 20.4 1.3 1 0 0 1 1 1 0 GPCR-chaperone FAM60A PF15396.1 CDI83376.1 - 6.6 6.4 32.3 11 5.7 22.4 1.4 1 0 0 1 1 1 0 Protein Family FAM60A Neur_chan_memb PF02932.11 CDI83376.1 - 6.7 6.5 29.0 7.3 6.3 20.1 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region ubiquitin PF00240.18 CDI83400.1 - 0.0064 15.8 2.8 0.01 15.1 1.9 1.4 1 0 0 1 1 1 1 Ubiquitin family Spt20 PF12090.3 CDI83400.1 - 0.17 11.2 2.7 0.24 10.7 1.9 1.3 1 0 0 1 1 1 0 Spt20 family API5 PF05918.6 CDI83400.1 - 0.52 8.7 4.2 0.67 8.3 2.9 1.2 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) Suf PF05843.9 CDI83400.1 - 0.6 9.7 5.4 0.94 9.1 3.8 1.4 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) TFIIA PF03153.8 CDI83400.1 - 6.8 6.4 21.8 11 5.8 15.1 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Metallothio_2 PF01439.13 CDI83403.1 - 0.0024 18.3 6.6 0.041 14.4 0.2 2.7 2 0 0 2 2 2 2 Metallothionein SIT PF15330.1 CDI83403.1 - 0.78 9.9 13.5 0.047 13.8 5.3 1.9 2 0 0 2 2 2 0 SHP2-interacting transmembrane adaptor protein, SIT Calc_CGRP_IAPP PF00214.14 CDI83403.1 - 1.5 8.8 9.9 0.12 12.3 2.7 2.2 2 0 0 2 2 2 0 Calcitonin / CGRP / IAPP family DUF3628 PF12300.3 CDI83403.1 - 4.6 7.2 18.3 2.5 8.1 4.9 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3628) RRM_1 PF00076.17 CDI83404.1 - 2.1e-08 33.6 0.0 3.9e-08 32.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CDI83404.1 - 1.9e-06 27.7 0.0 3.9e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CDI83404.1 - 0.014 15.1 0.0 0.029 14.2 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ycf1 PF05758.7 CDI83404.1 - 0.27 8.8 9.2 0.32 8.6 6.4 1.1 1 0 0 1 1 1 0 Ycf1 SAPS PF04499.10 CDI83404.1 - 0.67 8.5 10.6 0.88 8.1 7.4 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Mem_trans PF03547.13 CDI83404.1 - 0.83 7.8 3.2 1.5 7.0 2.2 1.5 1 0 0 1 1 1 0 Membrane transport protein DUF1180 PF06679.7 CDI83406.1 - 1.8 8.4 6.3 0.22 11.4 1.2 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1180) Shadoo PF14999.1 CDI83406.1 - 8.1 6.3 14.2 0.54 10.1 6.1 1.8 2 0 0 2 2 2 0 Shadow of prion protein, neuroprotective RskA PF10099.4 CDI83424.1 - 0.0033 17.1 0.7 0.0044 16.7 0.5 1.2 1 0 0 1 1 1 1 Anti-sigma-K factor rskA Med15 PF09606.5 CDI83424.1 - 0.019 13.1 10.1 0.021 13.0 7.0 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF4192 PF13830.1 CDI83424.1 - 0.02 14.5 4.4 0.025 14.2 3.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4192) Sporozoite_P67 PF05642.6 CDI83424.1 - 0.04 11.7 7.3 0.048 11.5 5.0 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Macoilin PF09726.4 CDI83424.1 - 0.063 11.5 11.0 0.085 11.1 7.6 1.2 1 0 0 1 1 1 0 Transmembrane protein RRM_1 PF00076.17 CDI83424.1 - 0.064 12.8 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2681 PF10883.3 CDI83424.1 - 0.086 13.0 3.3 0.16 12.1 2.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) DUF2749 PF10907.3 CDI83424.1 - 0.16 11.8 0.8 0.64 9.9 0.5 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF2749) RAP1 PF07218.6 CDI83424.1 - 0.17 9.9 10.2 0.18 9.9 7.0 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) PepSY_2 PF13670.1 CDI83424.1 - 1.5 8.7 4.9 3.1 7.7 3.4 1.4 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain P34-Arc PF04045.9 CDI83433.1 - 0.062 12.5 0.3 0.09 12.0 0.2 1.3 1 0 0 1 1 1 0 Arp2/3 complex, 34 kD subunit p34-Arc DUF4557 PF15101.1 CDI83433.1 - 5.4 6.7 10.5 1.4 8.6 5.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4557) Peptidase_M56 PF05569.6 CDI83443.1 - 1.3 7.9 10.8 1.4 7.7 7.5 1.1 1 0 0 1 1 1 0 BlaR1 peptidase M56 DUF912 PF06024.7 CDI83443.1 - 7.5 6.6 21.9 3.1 7.8 5.2 2.5 1 1 1 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) TFIIF_alpha PF05793.7 CDI83450.1 - 0.0065 14.9 48.3 0.0093 14.3 33.5 1.3 1 0 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Nop14 PF04147.7 CDI83450.1 - 0.0066 14.4 50.6 0.0077 14.2 35.1 1.1 1 0 0 1 1 1 1 Nop14-like family Chorion_2 PF03964.10 CDI83450.1 - 0.039 14.5 0.3 0.044 14.3 0.2 1.3 1 0 0 1 1 1 0 Chorion family 2 Mpp10 PF04006.7 CDI83450.1 - 0.062 11.6 46.5 0.07 11.4 32.2 1.0 1 0 0 1 1 1 0 Mpp10 protein YL1 PF05764.8 CDI83450.1 - 0.065 12.8 49.1 0.082 12.5 34.0 1.1 1 0 0 1 1 1 0 YL1 nuclear protein SDA1 PF05285.7 CDI83450.1 - 0.15 11.2 46.5 0.18 11.0 32.2 1.1 1 0 0 1 1 1 0 SDA1 PRP21_like_P PF12230.3 CDI83450.1 - 0.44 10.0 32.7 0.59 9.6 22.7 1.4 1 0 0 1 1 1 0 Pre-mRNA splicing factor PRP21 like protein MIP-T3 PF10243.4 CDI83450.1 - 0.48 8.8 55.0 0.53 8.7 38.1 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Merozoite_SPAM PF07133.6 CDI83450.1 - 0.57 10.0 61.8 0.81 9.5 42.8 1.2 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) Nop53 PF07767.6 CDI83450.1 - 0.67 8.8 51.5 0.8 8.6 35.7 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) CDC45 PF02724.9 CDI83450.1 - 0.69 7.8 42.8 0.89 7.5 29.7 1.0 1 0 0 1 1 1 0 CDC45-like protein Utp14 PF04615.8 CDI83450.1 - 0.74 7.8 44.7 0.82 7.7 31.0 1.0 1 0 0 1 1 1 0 Utp14 protein Daxx PF03344.10 CDI83450.1 - 0.74 8.2 45.9 0.89 7.9 31.8 1.1 1 0 0 1 1 1 0 Daxx Family SRP-alpha_N PF04086.8 CDI83450.1 - 0.8 9.0 37.3 0.89 8.8 25.8 1.0 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal PLRV_ORF5 PF01690.12 CDI83450.1 - 0.84 8.7 24.7 0.9 8.6 17.1 1.0 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein DUF4045 PF13254.1 CDI83450.1 - 0.92 8.7 23.8 0.98 8.6 16.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Caldesmon PF02029.10 CDI83450.1 - 1 7.7 50.6 1.1 7.6 35.1 1.1 1 0 0 1 1 1 0 Caldesmon Drc1-Sld2 PF11719.3 CDI83450.1 - 1.1 8.3 35.6 1.2 8.0 24.6 1.2 1 0 0 1 1 1 0 DNA replication and checkpoint protein GAGA_bind PF06217.7 CDI83450.1 - 1.3 8.8 27.1 1.5 8.6 18.8 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family SAPS PF04499.10 CDI83450.1 - 1.6 7.2 22.4 1.8 7.1 15.5 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF572 PF04502.8 CDI83450.1 - 2.7 7.1 35.7 3.2 6.8 24.7 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Hid1 PF12722.2 CDI83450.1 - 4.9 4.7 21.8 5 4.6 15.1 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Mem_trans PF03547.13 CDI83450.1 - 5.3 5.2 12.7 5.1 5.2 8.8 1.1 1 0 0 1 1 1 0 Membrane transport protein SOBP PF15279.1 CDI83450.1 - 7.4 6.8 7.4 8 6.7 5.1 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein alpha-hel2 PF14456.1 CDI83450.1 - 8.6 5.0 22.2 11 4.6 15.4 1.1 1 0 0 1 1 1 0 Alpha-helical domain 2 DUF3807 PF12720.2 CDI83450.1 - 8.6 6.4 36.3 13 5.9 25.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) Pex2_Pex12 PF04757.9 CDI83456.1 - 0.0015 17.9 23.3 0.015 14.6 16.1 2.7 1 1 0 1 1 1 1 Pex2 / Pex12 amino terminal region DUF1510 PF07423.6 CDI83456.1 - 0.0094 15.3 16.9 0.0094 15.3 11.7 4.0 3 1 0 3 3 3 2 Protein of unknown function (DUF1510) Ribosomal_60s PF00428.14 CDI83456.1 - 5.6 7.4 18.0 1.1 9.7 2.4 3.3 4 0 0 4 4 4 0 60s Acidic ribosomal protein DDRGK PF09756.4 CDI83462.1 - 0.00033 20.1 6.5 0.00033 20.1 4.5 1.9 2 0 0 2 2 2 1 DDRGK domain NPR3 PF03666.8 CDI83462.1 - 0.0016 17.0 0.6 0.0016 17.0 0.5 1.3 2 0 0 2 2 2 1 Nitrogen Permease regulator of amino acid transport activity 3 Ycf1 PF05758.7 CDI83462.1 - 0.055 11.1 3.6 0.07 10.8 2.5 1.2 1 0 0 1 1 1 0 Ycf1 Plasmodium_Vir PF05795.6 CDI83462.1 - 0.19 10.8 7.4 0.013 14.7 1.6 1.5 2 0 0 2 2 2 0 Plasmodium vivax Vir protein Ctr PF04145.10 CDI83462.1 - 0.48 10.4 2.6 0.51 10.3 0.2 2.0 1 1 1 2 2 2 0 Ctr copper transporter family PP_M1 PF03012.9 CDI83462.1 - 1.1 8.5 8.5 0.12 11.7 2.7 1.6 2 0 0 2 2 2 0 Phosphoprotein Paramyxo_ncap PF00973.14 CDI83462.1 - 1.3 7.6 5.1 1.9 7.0 3.6 1.3 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Med3 PF11593.3 CDI83462.1 - 1.6 7.8 11.0 2 7.5 7.6 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal BTV_NS2 PF04514.7 CDI83462.1 - 1.7 7.4 9.1 2 7.2 6.3 1.3 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Rhabdo_ncap PF00945.13 CDI83462.1 - 1.7 7.1 4.7 2.5 6.5 3.2 1.2 1 0 0 1 1 1 0 Rhabdovirus nucleocapsid protein FLO_LFY PF01698.11 CDI83462.1 - 1.7 7.3 12.2 2.2 7.0 8.5 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein DNA_pol_phi PF04931.8 CDI83462.1 - 2.3 5.8 18.7 3.1 5.4 12.9 1.1 1 0 0 1 1 1 0 DNA polymerase phi Raftlin PF15250.1 CDI83462.1 - 3.2 6.1 8.2 3.2 6.1 5.0 1.2 1 1 0 1 1 1 0 Raftlin DUF3959 PF13105.1 CDI83462.1 - 3.4 6.9 7.5 7.6 5.7 1.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3959) DUF2457 PF10446.4 CDI83462.1 - 4.2 6.0 19.4 0.4 9.3 10.3 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) Cytomega_UL84 PF06284.6 CDI83462.1 - 5 5.4 9.3 0.37 9.1 0.2 2.1 2 0 0 2 2 2 0 Cytomegalovirus UL84 protein Nop14 PF04147.7 CDI83462.1 - 5.2 4.8 18.8 6.5 4.5 13.0 1.2 1 0 0 1 1 1 0 Nop14-like family PBP1_TM PF14812.1 CDI83462.1 - 5.9 7.2 15.9 59 4.0 9.3 2.7 2 1 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Hex_IIIa PF02455.11 CDI83462.1 - 8.4 4.9 10.1 10 4.6 7.0 1.1 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) ketoacyl-synt PF00109.21 CDI83470.1 - 3.6e-64 216.6 0.0 7.8e-64 215.5 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 CDI83470.1 - 2.4e-49 167.4 0.2 7.9e-49 165.7 0.1 1.9 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 CDI83470.1 - 2.3e-40 138.2 1.2 4.4e-40 137.3 0.1 2.1 2 0 0 2 2 2 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 CDI83470.1 - 1.9e-30 105.1 0.2 4.2e-30 104.0 0.2 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain NAD_binding_4 PF07993.7 CDI83470.1 - 8.8e-29 100.1 0.0 9.8e-26 90.1 0.0 2.6 3 0 0 3 3 3 2 Male sterility protein PP-binding PF00550.20 CDI83470.1 - 5.4e-11 42.5 0.3 1.3e-10 41.4 0.2 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site Epimerase PF01370.16 CDI83470.1 - 4.5e-05 22.9 0.5 0.09 12.2 0.0 3.6 3 1 0 3 3 3 2 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 CDI83470.1 - 0.00024 20.1 0.0 0.0037 16.2 0.0 2.4 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 CDI83470.1 - 0.0054 16.7 3.5 2 8.3 0.2 3.2 3 0 0 3 3 3 2 NADH(P)-binding 3Beta_HSD PF01073.14 CDI83470.1 - 0.038 12.7 0.0 0.096 11.3 0.0 1.7 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family Activator_LAG-3 PF11498.3 CDI83471.1 - 0.2 10.3 79.5 0.067 11.9 1.7 2.4 2 0 0 2 2 2 0 Transcriptional activator LAG-3 Med15 PF09606.5 CDI83473.1 - 4.6e-05 21.8 115.1 7.3e-05 21.1 79.8 1.3 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal PAT1 PF09770.4 CDI83473.1 - 7.6e-05 21.1 94.5 9e-05 20.9 65.5 1.1 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 P12 PF12669.2 CDI83473.1 - 0.13 12.4 11.7 0.61 10.3 8.1 2.1 1 0 0 1 1 1 0 Virus attachment protein p12 family SR-25 PF10500.4 CDI83491.1 - 0.0058 16.1 27.8 0.0058 16.1 19.2 3.6 2 1 0 2 2 1 1 Nuclear RNA-splicing-associated protein Asp-B-Hydro_N PF05279.6 CDI83491.1 - 0.15 11.9 31.5 0.99 9.1 7.3 2.1 2 0 0 2 2 2 0 Aspartyl beta-hydroxylase N-terminal region GAGA_bind PF06217.7 CDI83491.1 - 0.2 11.5 28.7 0.22 11.4 5.6 2.2 2 0 0 2 2 2 0 GAGA binding protein-like family CENP-T PF15511.1 CDI83491.1 - 0.49 9.5 40.8 0.81 8.8 9.6 2.2 2 0 0 2 2 2 0 Centromere kinetochore component CENP-T Ycf1 PF05758.7 CDI83491.1 - 0.58 7.7 29.3 0.28 8.8 4.2 2.1 2 0 0 2 2 2 0 Ycf1 DUF4647 PF15504.1 CDI83491.1 - 1.7 7.3 33.7 0.59 8.9 7.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4647) Pox_Ag35 PF03286.9 CDI83491.1 - 1.8 8.0 29.7 1.4 8.3 8.4 2.4 2 0 0 2 2 2 0 Pox virus Ag35 surface protein SoxE PF06525.6 CDI83491.1 - 1.8 7.7 5.1 6.7 5.9 1.1 2.3 2 0 0 2 2 2 0 Sulfocyanin (SoxE) NPR3 PF03666.8 CDI83491.1 - 2.4 6.6 34.6 0.77 8.2 10.4 2.2 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF2052 PF09747.4 CDI83491.1 - 3.1 7.6 43.4 4.4 7.1 12.9 2.5 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) SRP-alpha_N PF04086.8 CDI83491.1 - 5.2 6.3 43.2 1.6 8.0 15.1 2.3 2 0 0 2 2 2 0 Signal recognition particle, alpha subunit, N-terminal Otopetrin PF03189.8 CDI83491.1 - 6.2 5.7 15.7 3.2 6.6 2.8 2.2 2 0 0 2 2 2 0 Otopetrin DUF808 PF05661.7 CDI83499.1 - 0.022 13.6 0.1 0.022 13.6 0.1 4.0 4 1 1 5 5 5 0 Protein of unknown function (DUF808) eIF3g PF12353.3 CDI83510.1 - 0.0029 17.5 4.4 0.0033 17.3 3.1 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G DUF533 PF04391.7 CDI83510.1 - 0.0095 15.3 11.0 0.01 15.2 7.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF533) VIT1 PF01988.14 CDI83510.1 - 0.011 15.2 1.8 0.012 15.1 1.2 1.0 1 0 0 1 1 1 0 VIT family Ctr PF04145.10 CDI83510.1 - 0.026 14.5 3.2 0.029 14.4 2.2 1.0 1 0 0 1 1 1 0 Ctr copper transporter family BLVR PF06375.6 CDI83510.1 - 0.03 14.1 5.6 0.034 13.9 3.9 1.0 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) RskA PF10099.4 CDI83510.1 - 0.052 13.2 4.6 0.061 13.0 3.2 1.1 1 0 0 1 1 1 0 Anti-sigma-K factor rskA CD20 PF04103.10 CDI83510.1 - 0.06 13.2 1.1 0.064 13.1 0.8 1.1 1 0 0 1 1 1 0 CD20-like family PEX11 PF05648.9 CDI83510.1 - 0.069 12.4 5.3 0.074 12.3 3.7 1.0 1 0 0 1 1 1 0 Peroxisomal biogenesis factor 11 (PEX11) DUF2512 PF10710.4 CDI83510.1 - 0.087 12.2 1.0 0.1 12.0 0.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2512) DUF912 PF06024.7 CDI83510.1 - 0.092 12.7 3.6 0.099 12.7 2.5 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) RAB3GAP2_N PF14655.1 CDI83510.1 - 0.16 10.9 9.2 0.19 10.6 6.4 1.1 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Topoisom_I_N PF02919.10 CDI83510.1 - 0.22 10.8 4.7 0.24 10.6 3.2 1.0 1 0 0 1 1 1 0 Eukaryotic DNA topoisomerase I, DNA binding fragment FHIPEP PF00771.15 CDI83510.1 - 0.24 9.6 5.8 0.24 9.6 4.0 1.0 1 0 0 1 1 1 0 FHIPEP family FAM176 PF14851.1 CDI83510.1 - 0.25 11.0 2.4 0.25 11.0 1.6 1.1 1 0 0 1 1 1 0 FAM176 family DUF1840 PF08895.6 CDI83510.1 - 0.27 11.2 7.4 0.32 11.0 5.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1840) Peptidase_S49_N PF08496.5 CDI83510.1 - 0.28 10.9 7.9 0.3 10.8 5.4 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal FimP PF09766.4 CDI83510.1 - 0.29 10.1 16.3 0.3 10.0 11.3 1.0 1 0 0 1 1 1 0 Fms-interacting protein zf-DHHC PF01529.15 CDI83510.1 - 0.3 10.4 4.2 0.31 10.4 2.9 1.1 1 0 0 1 1 1 0 DHHC palmitoyltransferase Dala_Dala_lig_N PF01820.16 CDI83510.1 - 0.3 11.3 2.7 0.3 11.4 1.8 1.1 1 0 0 1 1 1 0 D-ala D-ala ligase N-terminus PMSI1 PF15322.1 CDI83510.1 - 0.38 9.8 3.7 0.39 9.7 2.6 1.0 1 0 0 1 1 1 0 Protein missing in infertile sperm 1, putative DcuC PF03606.10 CDI83510.1 - 0.39 8.8 2.3 0.43 8.7 1.6 1.0 1 0 0 1 1 1 0 C4-dicarboxylate anaerobic carrier DUF4199 PF13858.1 CDI83510.1 - 0.42 10.5 5.6 0.43 10.4 3.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) TCP PF03634.8 CDI83510.1 - 0.43 10.9 10.7 0.48 10.8 7.4 1.0 1 0 0 1 1 1 0 TCP family transcription factor TOM13 PF08219.6 CDI83510.1 - 0.45 10.3 2.0 0.65 9.8 1.4 1.4 1 1 0 1 1 1 0 Outer membrane protein TOM13 EIIBC-GUT_N PF03612.9 CDI83510.1 - 0.48 10.0 6.9 0.51 9.9 4.8 1.0 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus DUF4449 PF14613.1 CDI83510.1 - 0.49 10.3 8.5 0.48 10.3 5.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4449) BRF1 PF07741.8 CDI83510.1 - 0.5 10.6 9.3 0.63 10.3 6.4 1.2 1 0 0 1 1 1 0 Brf1-like TBP-binding domain HA2 PF04408.18 CDI83510.1 - 0.53 10.3 2.6 0.67 10.0 1.8 1.1 1 0 0 1 1 1 0 Helicase associated domain (HA2) Tim54 PF11711.3 CDI83510.1 - 0.54 8.8 4.6 0.5 8.8 3.2 1.0 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 dsDNA_bind PF01984.15 CDI83510.1 - 0.56 10.2 21.2 0.68 9.9 14.7 1.2 1 0 0 1 1 1 0 Double-stranded DNA-binding domain Nucleoside_tran PF01733.13 CDI83510.1 - 0.56 9.3 2.5 0.55 9.3 1.7 1.0 1 0 0 1 1 1 0 Nucleoside transporter Folate_carrier PF01770.13 CDI83510.1 - 0.65 8.4 4.7 0.64 8.4 3.2 1.1 1 0 0 1 1 1 0 Reduced folate carrier Med13_N PF11597.3 CDI83510.1 - 0.66 8.5 8.3 0.68 8.5 5.8 1.0 1 0 0 1 1 1 0 Mediator complex subunit 13 N-terminal Glt_symporter PF03616.9 CDI83510.1 - 0.67 8.3 3.5 0.7 8.3 2.4 1.0 1 0 0 1 1 1 0 Sodium/glutamate symporter DUF3371 PF11851.3 CDI83510.1 - 0.69 10.5 13.0 0.77 10.4 9.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3371) Peroxin-13_N PF04088.8 CDI83510.1 - 0.71 9.8 3.4 0.8 9.6 2.4 1.1 1 0 0 1 1 1 0 Peroxin 13, N-terminal region Suf PF05843.9 CDI83510.1 - 0.75 9.4 12.1 0.74 9.4 8.4 1.0 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) CagX PF03524.10 CDI83510.1 - 0.93 8.7 6.3 0.88 8.8 4.4 1.0 1 0 0 1 1 1 0 Conjugal transfer protein DUF4446 PF14584.1 CDI83510.1 - 0.95 9.2 5.4 0.97 9.2 3.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) MDFI PF15316.1 CDI83510.1 - 1.3 8.9 5.5 1.3 8.9 3.8 1.0 1 0 0 1 1 1 0 MyoD family inhibitor OATP PF03137.15 CDI83510.1 - 1.3 6.9 5.6 1.3 7.0 3.9 1.0 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Spt20 PF12090.3 CDI83510.1 - 1.4 8.2 10.2 1.7 7.9 7.1 1.2 1 0 0 1 1 1 0 Spt20 family DDHD PF02862.12 CDI83510.1 - 1.5 8.5 6.4 1.5 8.5 4.4 1.0 1 0 0 1 1 1 0 DDHD domain DUF775 PF05603.7 CDI83510.1 - 1.6 8.2 9.2 1.6 8.2 6.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF775) Serinc PF03348.10 CDI83510.1 - 1.9 7.0 8.2 1.8 7.1 5.7 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) AIF_C PF14721.1 CDI83510.1 - 2 8.6 6.7 2.2 8.5 4.6 1.1 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term DUF4557 PF15101.1 CDI83510.1 - 2.1 8.1 16.5 2.1 8.1 11.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) HCV_NS5a_C PF12941.2 CDI83510.1 - 2.1 7.8 5.7 2.3 7.7 3.9 1.0 1 0 0 1 1 1 0 HCV NS5a protein C-terminal region DUF3812 PF12757.2 CDI83510.1 - 2.4 8.1 15.3 2.8 7.9 10.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3812) RR_TM4-6 PF06459.7 CDI83510.1 - 2.4 7.9 7.9 2.4 7.9 5.5 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 eIF_4EBP PF05456.6 CDI83510.1 - 2.5 7.8 7.0 2.9 7.5 4.9 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) Band_3_cyto PF07565.8 CDI83510.1 - 2.6 7.5 8.1 2.6 7.5 5.6 1.0 1 0 0 1 1 1 0 Band 3 cytoplasmic domain DUF4175 PF13779.1 CDI83510.1 - 2.6 5.6 23.9 2.7 5.5 16.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) RED_N PF07808.8 CDI83510.1 - 3.2 6.9 14.0 3.3 6.8 9.7 1.0 1 0 0 1 1 1 0 RED-like protein N-terminal region G0-G1_switch_2 PF15103.1 CDI83510.1 - 3.8 7.7 6.9 4.4 7.5 4.8 1.2 1 0 0 1 1 1 0 G0/G1 switch protein 2 Gag_spuma PF03276.9 CDI83510.1 - 4.1 5.6 16.2 4.3 5.5 11.3 1.0 1 0 0 1 1 1 0 Spumavirus gag protein DUF3464 PF11947.3 CDI83510.1 - 4.4 6.7 6.4 4.8 6.6 4.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) EphA2_TM PF14575.1 CDI83510.1 - 5 7.5 6.9 8.4 6.8 4.8 1.5 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain SprA-related PF12118.3 CDI83510.1 - 5.2 6.3 22.9 5.4 6.2 15.8 1.1 1 0 0 1 1 1 0 SprA-related family PAT1 PF09770.4 CDI83510.1 - 5.5 5.0 19.9 5.1 5.1 13.8 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 F-protein PF00469.15 CDI83510.1 - 6 6.1 9.3 6.3 6.0 6.4 1.0 1 0 0 1 1 1 0 Negative factor, (F-Protein) or Nef PsiA PF06952.6 CDI83510.1 - 6.5 5.7 11.9 6.7 5.7 8.2 1.1 1 0 0 1 1 1 0 PsiA protein DUF3682 PF12446.3 CDI83510.1 - 7.2 6.9 18.1 8.6 6.6 12.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) Pex16 PF08610.5 CDI83510.1 - 7.3 5.4 8.2 7.7 5.4 5.7 1.0 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) Baculo_PP31 PF05311.6 CDI83510.1 - 7.8 5.6 10.6 8.5 5.5 7.3 1.0 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) Prog_receptor PF02161.10 CDI83510.1 - 8.5 5.0 7.3 9.8 4.8 5.0 1.1 1 0 0 1 1 1 0 Progesterone receptor DivIC PF04977.10 CDI83510.1 - 9.6 5.7 14.8 14 5.2 10.3 1.3 1 0 0 1 1 1 0 Septum formation initiator rve PF00665.21 CDI83526.1 - 6.5e-13 48.8 0.0 8.7e-13 48.4 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.1 CDI83526.1 - 0.11 11.9 0.1 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 Integrase core domain RVT_1 PF00078.22 CDI83527.1 - 4e-11 42.6 0.0 9.8e-11 41.4 0.0 1.7 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) gag-asp_proteas PF13975.1 CDI83528.1 - 2e-08 33.9 0.0 4.1e-08 32.9 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 CDI83528.1 - 7.8e-08 32.7 0.0 1.5e-07 31.8 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.15 CDI83528.1 - 0.00079 19.3 0.0 0.0017 18.2 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.5 CDI83528.1 - 0.099 12.2 0.0 0.25 10.9 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease RVP_2 PF08284.6 CDI83528.1 - 0.12 12.3 0.0 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease Fra10Ac1 PF09725.4 CDI83530.1 - 6.6e-14 51.9 0.9 7.4e-10 38.9 0.0 2.5 2 0 0 2 2 2 2 Folate-sensitive fragile site protein Fra10Ac1 Ribosomal_60s PF00428.14 CDI83554.1 - 0.039 14.3 19.8 1 9.8 2.3 2.5 2 0 0 2 2 2 0 60s Acidic ribosomal protein Pyr_redox_2 PF07992.9 CDI83554.1 - 7.6 6.3 6.4 16 5.3 0.2 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Presenilin PF01080.12 CDI83556.1 - 0.004 16.0 2.3 0.004 16.0 1.6 1.8 2 0 0 2 2 2 1 Presenilin SGT1 PF07093.6 CDI83556.1 - 0.012 14.0 5.7 0.015 13.7 3.9 1.1 1 0 0 1 1 1 0 SGT1 protein TT_ORF1 PF02956.9 CDI83556.1 - 0.018 13.5 4.6 0.02 13.3 3.2 1.1 1 0 0 1 1 1 0 TT viral orf 1 Peptidase_S49_N PF08496.5 CDI83556.1 - 0.045 13.5 5.6 0.087 12.6 3.8 1.5 1 0 0 1 1 1 0 Peptidase family S49 N-terminal SKI PF01202.17 CDI83556.1 - 0.079 12.8 2.4 0.13 12.1 1.7 1.3 1 0 0 1 1 1 0 Shikimate kinase Suf PF05843.9 CDI83556.1 - 2.6 7.7 11.7 5 6.7 8.1 1.4 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) PspA_IM30 PF04012.7 CDI83572.1 - 4.1e-05 23.0 15.2 4.1e-05 23.0 10.6 2.2 2 0 0 2 2 2 1 PspA/IM30 family OST-HTH PF12872.2 CDI83572.1 - 0.011 15.5 0.5 0.025 14.3 0.3 1.6 1 0 0 1 1 1 0 OST-HTH/LOTUS domain ATP-synt_D PF01813.12 CDI83572.1 - 0.021 14.4 1.6 0.021 14.4 1.1 3.1 1 1 1 3 3 3 0 ATP synthase subunit D TMF_DNA_bd PF12329.3 CDI83572.1 - 0.081 12.7 48.9 0.32 10.8 2.9 4.4 2 1 2 4 4 4 0 TATA element modulatory factor 1 DNA binding Filament PF00038.16 CDI83572.1 - 0.45 9.9 37.6 0.023 14.1 12.0 2.0 1 1 1 2 2 2 0 Intermediate filament protein DUF3450 PF11932.3 CDI83572.1 - 0.81 8.9 25.4 0.11 11.7 7.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) Syntaxin-6_N PF09177.6 CDI83572.1 - 1 9.8 19.7 1.7 9.0 3.1 3.2 1 1 2 3 3 3 0 Syntaxin 6, N-terminal CENP-F_leu_zip PF10473.4 CDI83572.1 - 2.1 8.2 44.2 4 7.2 10.1 3.0 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 IncA PF04156.9 CDI83572.1 - 2.1 7.9 43.2 0.12 11.9 15.9 2.4 1 1 1 2 2 2 0 IncA protein GAS PF13851.1 CDI83572.1 - 2.1 7.4 38.6 0.86 8.7 14.0 2.3 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Baculo_PEP_C PF04513.7 CDI83572.1 - 2.5 7.9 10.6 4.6 7.0 0.5 2.8 2 1 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4407 PF14362.1 CDI83572.1 - 3.2 6.6 29.3 3.7 6.4 8.7 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Spc7 PF08317.6 CDI83572.1 - 6.2 5.3 35.0 3.3 6.2 13.6 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein HrpB7 PF09486.5 CDI83572.1 - 7.2 6.5 31.4 32 4.4 12.5 2.6 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB7) UPF0564 PF10595.4 CDI83584.1 - 0.0044 15.9 21.9 0.0059 15.5 15.2 1.2 1 0 0 1 1 1 1 Uncharacterised protein family UPF0564 PPP4R2 PF09184.6 CDI83584.1 - 0.0051 16.4 13.1 0.0051 16.4 9.1 2.1 2 0 0 2 2 2 1 PPP4R2 Beta_propel PF09826.4 CDI83584.1 - 0.13 10.5 3.2 0.18 10.0 2.2 1.2 1 0 0 1 1 1 0 Beta propeller domain Na_trans_assoc PF06512.8 CDI83584.1 - 0.19 11.6 22.8 0.31 10.9 15.8 1.3 1 0 0 1 1 1 0 Sodium ion transport-associated Med15 PF09606.5 CDI83584.1 - 0.31 9.1 46.7 0.39 8.8 32.4 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal MOR2-PAG1_N PF14222.1 CDI83584.1 - 0.79 8.3 8.5 1.1 7.8 5.9 1.1 1 0 0 1 1 1 0 Cell morphogenesis N-terminal Peptidase_S15 PF02129.13 CDI83584.1 - 1.5 8.1 10.3 2.6 7.3 7.1 1.4 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) DUF2052 PF09747.4 CDI83584.1 - 7.3 6.4 35.4 7 6.5 12.7 2.3 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) Dala_Dala_lig_N PF01820.16 CDI83584.1 - 8.9 6.6 10.7 10 6.4 3.6 2.5 2 0 0 2 2 2 0 D-ala D-ala ligase N-terminus FAM60A PF15396.1 CDI83584.1 - 9.5 5.9 18.6 10 5.8 0.8 2.2 2 0 0 2 2 2 0 Protein Family FAM60A Pkinase PF00069.20 CDI83591.1 - 2.9e-33 115.1 0.0 1.1e-16 60.8 0.0 3.1 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CDI83591.1 - 2.1e-09 36.8 0.0 0.0044 16.1 0.0 3.9 3 0 0 3 3 3 3 Protein tyrosine kinase NARP1 PF12569.3 CDI83591.1 - 1.8 7.2 16.0 5.1 5.7 11.1 1.7 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 IncA PF04156.9 CDI83625.1 - 0.00067 19.3 14.5 0.00099 18.7 10.1 1.2 1 0 0 1 1 1 1 IncA protein PAT1 PF09770.4 CDI83625.1 - 0.038 12.2 23.1 0.043 12.0 16.0 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 CDC45 PF02724.9 CDI83625.1 - 0.083 10.9 21.8 0.11 10.5 15.1 1.1 1 0 0 1 1 1 0 CDC45-like protein Plasmodium_Vir PF05795.6 CDI83625.1 - 0.11 11.7 10.1 0.15 11.2 7.0 1.3 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Ycf1 PF05758.7 CDI83625.1 - 0.13 9.9 10.4 0.13 9.9 7.2 1.0 1 0 0 1 1 1 0 Ycf1 Utp14 PF04615.8 CDI83625.1 - 0.13 10.4 22.9 0.15 10.2 15.9 1.1 1 0 0 1 1 1 0 Utp14 protein DUF4647 PF15504.1 CDI83625.1 - 0.39 9.5 21.0 0.55 9.0 14.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4647) Hid1 PF12722.2 CDI83625.1 - 0.5 7.9 20.6 0.62 7.6 14.3 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Tetraspannin PF00335.15 CDI83625.1 - 0.76 9.0 4.1 1 8.5 2.8 1.2 1 0 0 1 1 1 0 Tetraspanin family SAPS PF04499.10 CDI83625.1 - 0.8 8.2 14.0 1.1 7.8 9.7 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Ndc1_Nup PF09531.5 CDI83625.1 - 1.2 7.5 20.6 1.6 7.0 14.3 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup eIF-3_zeta PF05091.7 CDI83625.1 - 1.4 7.4 16.4 1.7 7.2 11.4 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) AvrE PF11725.3 CDI83625.1 - 2.1 5.2 32.1 2.3 5.1 22.3 1.1 1 0 0 1 1 1 0 Pathogenicity factor DivIC PF04977.10 CDI83625.1 - 2.1 7.8 12.4 4.3 6.9 8.6 1.6 1 0 0 1 1 1 0 Septum formation initiator PLRV_ORF5 PF01690.12 CDI83625.1 - 2.3 7.2 19.7 2.9 6.9 13.6 1.2 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein DDRGK PF09756.4 CDI83625.1 - 2.8 7.2 21.2 4.6 6.6 14.7 1.3 1 0 0 1 1 1 0 DDRGK domain Dicty_REP PF05086.7 CDI83625.1 - 3 5.4 13.4 3.4 5.3 9.3 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Y_phosphatase3 PF13350.1 CDI83625.1 - 3.9 7.6 9.2 6.7 6.9 6.4 1.5 1 0 0 1 1 1 0 Tyrosine phosphatase family DUF2146 PF10220.4 CDI83625.1 - 6.1 4.6 15.8 6.6 4.5 10.9 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2146) DUF4638 PF15472.1 CDI83625.1 - 7 6.1 20.1 12 5.3 13.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) DUF4613 PF15390.1 CDI83625.1 - 8.8 4.3 17.8 11 4.0 12.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) PAT1 PF09770.4 CDI83626.1 - 0.38 8.9 58.4 0.47 8.6 40.5 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SOBP PF15279.1 CDI83626.1 - 1.1 9.5 33.2 1.4 9.2 23.0 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein PA26 PF04636.8 CDI83626.1 - 2.7 6.5 16.8 3.4 6.2 11.6 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Trp_oprn_chp PF09534.5 CDI83626.1 - 5.1 6.6 11.5 0.43 10.1 0.7 2.1 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Herpes_UL87 PF03043.9 CDI83626.1 - 6.3 5.0 18.7 7.7 4.7 13.0 1.1 1 0 0 1 1 1 0 Herpesvirus UL87 family Asp-B-Hydro_N PF05279.6 CDI83626.1 - 9.6 5.9 16.3 13 5.5 11.3 1.3 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region DUF3138 PF11336.3 CDI83641.1 - 0.018 13.2 16.9 0.0061 14.7 9.3 1.9 1 1 0 2 2 2 0 Protein of unknown function (DUF3138) FlxA PF14282.1 CDI83641.1 - 0.1 12.5 27.9 0.44 10.5 16.6 2.1 2 0 0 2 2 2 0 FlxA-like protein PIH1 PF08190.7 CDI83641.1 - 1.9 7.8 11.9 1.9 7.8 8.2 1.1 1 0 0 1 1 1 0 pre-RNA processing PIH1/Nop17 DUF966 PF06136.8 CDI83641.1 - 2 7.7 9.5 2.4 7.5 6.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF966) eIF_4EBP PF05456.6 CDI83641.1 - 2 8.1 5.4 1.8 8.2 2.6 1.6 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) Shadoo PF14999.1 CDI83641.1 - 2.6 7.9 5.6 4.7 7.0 3.9 1.5 1 1 0 1 1 1 0 Shadow of prion protein, neuroprotective DNA_pol_viral_N PF00242.12 CDI83641.1 - 4.9 6.0 9.6 5.3 5.9 6.6 1.0 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain Band_3_cyto PF07565.8 CDI83641.1 - 6.1 6.2 8.9 6.7 6.1 6.2 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain DUF4557 PF15101.1 CDI83641.1 - 6.9 6.4 10.5 7.9 6.2 7.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) Band_3_cyto PF07565.8 CDI83672.1 - 0.0085 15.6 35.3 0.69 9.3 7.7 3.4 3 0 0 3 3 3 3 Band 3 cytoplasmic domain AAA_11 PF13086.1 CDI83672.1 - 0.022 14.3 36.4 0.089 12.3 1.5 3.4 3 0 0 3 3 3 0 AAA domain DUF1510 PF07423.6 CDI83672.1 - 0.27 10.5 38.1 1.9 7.8 8.5 4.5 4 1 0 4 4 4 0 Protein of unknown function (DUF1510) Gti1_Pac2 PF09729.4 CDI83672.1 - 0.72 9.6 19.9 3.7 7.4 0.0 3.4 3 0 0 3 3 3 0 Gti1/Pac2 family SAGA-Tad1 PF12767.2 CDI83672.1 - 0.74 9.4 32.0 0.95 9.0 1.0 3.4 3 0 0 3 3 3 0 Transcriptional regulator of RNA polII, SAGA, subunit zf-DHHC PF01529.15 CDI83672.1 - 0.84 9.0 9.0 23 4.3 1.3 3.5 3 0 0 3 3 3 0 DHHC palmitoyltransferase DUF2052 PF09747.4 CDI83672.1 - 1.3 8.8 46.2 1.6 8.5 4.0 3.5 3 0 0 3 3 3 0 Coiled-coil domain containing protein (DUF2052) Peptidase_S49_N PF08496.5 CDI83672.1 - 2.1 8.1 42.7 0.57 9.9 0.8 4.4 4 0 0 4 4 4 0 Peptidase family S49 N-terminal Plasmodium_Vir PF05795.6 CDI83672.1 - 2.5 7.2 12.1 3.2 6.8 1.2 3.3 3 0 0 3 3 3 0 Plasmodium vivax Vir protein F-protein PF00469.15 CDI83686.1 - 3.1 7.1 8.6 0.51 9.6 0.7 2.5 2 0 0 2 2 2 0 Negative factor, (F-Protein) or Nef Leo1 PF04004.8 CDI83692.1 - 2.9e-10 40.1 1.6 3.8e-10 39.7 0.0 2.0 2 0 0 2 2 2 1 Leo1-like protein Suf PF05843.9 CDI83692.1 - 0.11 12.1 2.9 0.22 11.2 2.0 1.4 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF1510 PF07423.6 CDI83694.1 - 3.7 6.8 33.0 5.4 6.3 22.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) SR-25 PF10500.4 CDI83700.1 - 5.1 6.4 94.9 0.02 14.3 12.4 4.1 2 1 2 4 4 4 0 Nuclear RNA-splicing-associated protein SR-25 PF10500.4 CDI83705.1 - 3.3e-06 26.7 30.6 4.6e-06 26.2 21.2 1.2 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Nop53 PF07767.6 CDI83705.1 - 0.0041 16.1 10.3 0.0045 16.0 7.1 1.0 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) Serinc PF03348.10 CDI83705.1 - 0.028 13.1 7.8 0.028 13.1 5.4 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) FimP PF09766.4 CDI83705.1 - 0.031 13.3 11.9 0.038 13.0 8.2 1.3 1 0 0 1 1 1 0 Fms-interacting protein Suf PF05843.9 CDI83705.1 - 0.032 13.9 14.3 0.037 13.7 9.9 1.0 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF913 PF06025.7 CDI83705.1 - 0.036 12.8 5.4 0.036 12.8 3.7 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Zip PF02535.17 CDI83705.1 - 0.046 12.7 4.8 0.047 12.7 3.3 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter DUF1510 PF07423.6 CDI83705.1 - 0.049 12.9 10.7 0.055 12.8 7.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) CAF-1_p150 PF11600.3 CDI83705.1 - 0.056 12.8 25.6 0.073 12.4 17.8 1.0 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF4557 PF15101.1 CDI83705.1 - 0.069 12.9 13.2 0.079 12.7 9.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) RIC3 PF15361.1 CDI83705.1 - 0.076 13.2 6.9 0.087 13.0 4.8 1.1 1 0 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 Raftlin PF15250.1 CDI83705.1 - 0.077 11.5 11.5 0.085 11.3 7.9 1.0 1 0 0 1 1 1 0 Raftlin Med15 PF09606.5 CDI83705.1 - 0.079 11.1 20.6 0.082 11.1 14.3 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF4614 PF15391.1 CDI83705.1 - 0.083 12.6 17.0 0.099 12.4 11.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) DUF4603 PF15376.1 CDI83705.1 - 0.089 9.9 19.1 0.11 9.6 13.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) Pex14_N PF04695.8 CDI83705.1 - 0.091 12.8 18.1 0.13 12.3 12.6 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF4448 PF14610.1 CDI83705.1 - 0.094 12.1 1.1 0.11 11.9 0.7 1.2 1 1 0 1 1 1 0 Protein of unknown function (DUF4448) FLO_LFY PF01698.11 CDI83705.1 - 0.095 11.5 8.7 0.099 11.4 6.0 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein PGA2 PF07543.7 CDI83705.1 - 0.12 12.1 7.0 0.15 11.8 4.8 1.1 1 0 0 1 1 1 0 Protein trafficking PGA2 SprA-related PF12118.3 CDI83705.1 - 0.12 11.6 25.5 0.17 11.2 17.7 1.1 1 0 0 1 1 1 0 SprA-related family Nop14 PF04147.7 CDI83705.1 - 0.13 10.1 11.3 0.15 9.9 7.8 1.0 1 0 0 1 1 1 0 Nop14-like family NAM-associated PF14303.1 CDI83705.1 - 0.14 12.4 14.0 0.18 12.1 9.7 1.1 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain DUF3827 PF12877.2 CDI83705.1 - 0.17 9.9 16.6 0.2 9.7 11.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) Ycf1 PF05758.7 CDI83705.1 - 0.21 9.2 7.3 0.22 9.2 5.1 1.0 1 0 0 1 1 1 0 Ycf1 Peptidase_S49_N PF08496.5 CDI83705.1 - 0.26 11.0 5.5 0.31 10.8 3.8 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Macoilin PF09726.4 CDI83705.1 - 0.29 9.3 15.4 0.43 8.8 10.7 1.2 1 0 0 1 1 1 0 Transmembrane protein CKAP2_C PF15297.1 CDI83705.1 - 0.38 9.5 11.6 0.43 9.3 8.0 1.0 1 0 0 1 1 1 0 Cytoskeleton-associated protein 2 C-terminus Bul1_N PF04425.7 CDI83705.1 - 0.39 9.2 11.1 0.46 8.9 7.7 1.0 1 0 0 1 1 1 0 Bul1 N terminus DUF3417 PF11897.3 CDI83705.1 - 0.4 10.6 4.0 0.5 10.3 2.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3417) DUF2146 PF10220.4 CDI83705.1 - 0.42 8.5 12.4 0.46 8.4 8.6 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2146) PRP3 PF08572.5 CDI83705.1 - 0.53 9.6 12.4 0.6 9.4 8.6 1.0 1 0 0 1 1 1 0 pre-mRNA processing factor 3 (PRP3) zf-DHHC PF01529.15 CDI83705.1 - 0.58 9.5 2.5 0.66 9.3 1.7 1.3 1 0 0 1 1 1 0 DHHC palmitoyltransferase NARP1 PF12569.3 CDI83705.1 - 0.72 8.5 10.4 0.82 8.3 7.2 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Cwf_Cwc_15 PF04889.7 CDI83705.1 - 0.79 9.3 14.5 1 9.0 10.0 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF737 PF05300.6 CDI83705.1 - 0.8 9.6 19.8 0.94 9.4 13.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF737) CDK2AP PF09806.4 CDI83705.1 - 0.81 9.8 17.3 1.2 9.3 12.0 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein DUF4220 PF13968.1 CDI83705.1 - 0.84 8.6 5.9 0.94 8.5 4.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4220) CDC45 PF02724.9 CDI83705.1 - 0.85 7.5 19.8 1.1 7.2 13.7 1.0 1 0 0 1 1 1 0 CDC45-like protein OATP PF03137.15 CDI83705.1 - 0.88 7.5 5.8 0.93 7.4 4.0 1.2 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family AIF_C PF14721.1 CDI83705.1 - 0.92 9.7 7.7 1.4 9.1 5.3 1.3 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Baculo_PP31 PF05311.6 CDI83705.1 - 0.98 8.6 13.8 1.2 8.4 9.5 1.1 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) DUF3337 PF11816.3 CDI83705.1 - 1 8.6 11.4 1.2 8.4 7.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3337) XRCC4 PF06632.7 CDI83705.1 - 1.1 8.0 10.2 1.2 7.8 7.0 1.0 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 Sec62 PF03839.11 CDI83705.1 - 1.1 8.6 7.7 1.2 8.4 5.3 1.0 1 0 0 1 1 1 0 Translocation protein Sec62 AUX_IAA PF02309.11 CDI83705.1 - 1.1 8.9 11.4 1.3 8.7 7.9 1.0 1 0 0 1 1 1 0 AUX/IAA family DUF2201_N PF13203.1 CDI83705.1 - 1.2 8.2 15.9 1.4 8.0 11.0 1.0 1 0 0 1 1 1 0 Putative metallopeptidase domain DUF4228 PF14009.1 CDI83705.1 - 1.2 9.2 12.1 1.5 8.9 8.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4228) NPR3 PF03666.8 CDI83705.1 - 1.3 7.4 14.3 1.5 7.2 9.9 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Cellulose_synt PF03552.9 CDI83705.1 - 1.5 6.9 4.5 1.7 6.8 3.2 1.0 1 0 0 1 1 1 0 Cellulose synthase Apt1 PF10351.4 CDI83705.1 - 1.6 7.5 20.4 1.9 7.2 14.1 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain F-protein PF00469.15 CDI83705.1 - 1.6 8.0 11.3 1.8 7.8 7.8 1.1 1 0 0 1 1 1 0 Negative factor, (F-Protein) or Nef SAGA-Tad1 PF12767.2 CDI83705.1 - 1.6 8.3 15.3 1.9 8.0 10.6 1.1 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit Nucleo_P87 PF07267.6 CDI83705.1 - 1.7 7.2 8.4 2 7.0 5.8 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Gag_spuma PF03276.9 CDI83705.1 - 1.7 6.8 23.0 2 6.6 15.9 1.0 1 0 0 1 1 1 0 Spumavirus gag protein SID-1_RNA_chan PF13965.1 CDI83705.1 - 1.9 6.5 4.8 1.9 6.5 3.3 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DDHD PF02862.12 CDI83705.1 - 2.3 7.9 17.6 2.8 7.6 12.2 1.0 1 0 0 1 1 1 0 DDHD domain FAM60A PF15396.1 CDI83705.1 - 2.6 7.7 12.6 4.3 7.0 8.7 1.4 1 0 0 1 1 1 0 Protein Family FAM60A DUF1675 PF07897.6 CDI83705.1 - 2.9 7.6 15.0 3.5 7.4 10.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) Rubella_Capsid PF05750.6 CDI83705.1 - 3 7.1 7.3 3.4 6.9 5.1 1.0 1 0 0 1 1 1 0 Rubella capsid protein AAR2 PF05282.6 CDI83705.1 - 3.1 6.6 10.4 3.7 6.3 7.2 1.1 1 0 0 1 1 1 0 AAR2 protein OmpH PF03938.9 CDI83705.1 - 3.3 7.6 21.3 3.9 7.3 14.8 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) RAB3GAP2_N PF14655.1 CDI83705.1 - 3.4 6.5 11.4 4.4 6.1 7.9 1.3 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Paramyxo_ncap PF00973.14 CDI83705.1 - 3.4 6.2 7.7 3.7 6.1 5.4 1.0 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein DUF605 PF04652.11 CDI83705.1 - 3.5 6.9 19.2 4.2 6.6 13.3 1.0 1 0 0 1 1 1 0 Vta1 like THRAP3_BCLAF1 PF15440.1 CDI83705.1 - 3.6 6.1 29.7 4.2 5.9 20.6 1.0 1 0 0 1 1 1 0 THRAP3/BCLAF1 family Bul1_C PF04426.7 CDI83705.1 - 4 6.5 12.5 4.7 6.3 8.7 1.1 1 0 0 1 1 1 0 Bul1 C terminus SpoVR PF04293.8 CDI83705.1 - 4.1 5.6 9.5 4.7 5.4 6.6 1.0 1 0 0 1 1 1 0 SpoVR like protein Rtf2 PF04641.7 CDI83705.1 - 4.2 6.4 14.7 4.9 6.2 10.2 1.0 1 0 0 1 1 1 0 Rtf2 RING-finger SOBP PF15279.1 CDI83705.1 - 4.3 7.6 14.7 5.1 7.3 10.2 1.0 1 0 0 1 1 1 0 Sine oculis-binding protein PsbW PF07123.7 CDI83705.1 - 4.4 7.3 7.9 5.1 7.1 5.5 1.1 1 0 0 1 1 1 0 Photosystem II reaction centre W protein (PsbW) Sox_N PF12444.3 CDI83705.1 - 4.5 8.4 19.3 6.9 7.8 13.3 1.3 1 0 0 1 1 1 0 Sox developmental protein N terminal Pheromone PF08015.6 CDI83705.1 - 4.6 8.1 9.4 11 6.9 6.5 1.6 1 0 0 1 1 1 0 Fungal mating-type pheromone DUF515 PF04415.7 CDI83705.1 - 4.7 5.3 22.2 5.3 5.1 15.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) MRP-S31 PF15433.1 CDI83705.1 - 4.9 6.4 14.2 5.8 6.2 9.9 1.0 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 Band_3_cyto PF07565.8 CDI83705.1 - 5 6.5 12.2 6.2 6.2 8.5 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Neur_chan_memb PF02932.11 CDI83705.1 - 5 6.9 9.3 5.9 6.6 6.4 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Spore_coat_CotO PF14153.1 CDI83705.1 - 5.1 6.4 16.8 6.5 6.1 11.7 1.2 1 0 0 1 1 1 0 Spore coat protein CotO Glyco_transf_15 PF01793.11 CDI83705.1 - 5.2 5.9 10.2 6.2 5.6 7.1 1.0 1 0 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase FNIP_N PF14636.1 CDI83705.1 - 5.2 7.5 17.9 6.7 7.1 12.4 1.1 1 0 0 1 1 1 0 Folliculin-interacting protein N-terminus Presenilin PF01080.12 CDI83705.1 - 5.2 5.7 13.3 6.1 5.5 9.2 1.0 1 0 0 1 1 1 0 Presenilin DUF3464 PF11947.3 CDI83705.1 - 5.4 6.4 12.4 7.5 6.0 8.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) DUF2413 PF10310.4 CDI83705.1 - 5.9 5.5 18.3 7 5.3 12.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) DUF572 PF04502.8 CDI83705.1 - 5.9 6.0 17.2 7.5 5.6 11.9 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF4407 PF14362.1 CDI83705.1 - 6 5.7 8.9 6.7 5.5 6.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF3449 PF11931.3 CDI83705.1 - 6.3 6.2 11.8 8.6 5.8 8.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3449) eIF-3_zeta PF05091.7 CDI83705.1 - 6.7 5.2 13.1 7.2 5.1 9.1 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) AvrE PF11725.3 CDI83705.1 - 8.2 3.3 16.4 9.3 3.1 11.4 1.0 1 0 0 1 1 1 0 Pathogenicity factor Ndc1_Nup PF09531.5 CDI83706.1 - 3.6 5.9 29.8 4.3 5.6 20.6 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF966 PF06136.8 CDI83706.1 - 3.9 6.7 28.1 4.4 6.6 19.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Init_tRNA_PT PF04179.7 CDI83706.1 - 7.1 5.3 20.9 8.5 5.1 14.5 1.1 1 0 0 1 1 1 0 Initiator tRNA phosphoribosyl transferase DUF3597 PF12200.3 CDI83707.1 - 0.022 15.1 6.2 0.022 15.1 4.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3597) Med15 PF09606.5 CDI83707.1 - 0.026 12.7 85.0 0.032 12.4 58.9 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal CAF-1_p150 PF11600.3 CDI83707.1 - 0.17 11.2 25.1 0.25 10.6 17.4 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Anoctamin PF04547.7 CDI83707.1 - 0.4 9.2 16.8 0.46 9.0 11.6 1.1 1 0 0 1 1 1 0 Calcium-activated chloride channel Tetraspannin PF00335.15 CDI83707.1 - 1.3 8.2 5.1 2 7.6 3.5 1.4 1 1 0 1 1 1 0 Tetraspanin family Band_3_cyto PF07565.8 CDI83707.1 - 2.4 7.5 30.6 2.8 7.3 21.2 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain G-7-MTase PF12803.2 CDI83707.1 - 2.6 7.1 13.3 3 6.9 9.2 1.2 1 0 0 1 1 1 0 mRNA (guanine-7-)methyltransferase (G-7-MTase) MRP-S31 PF15433.1 CDI83707.1 - 3 7.1 32.9 3.9 6.7 22.8 1.1 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 GAGA_bind PF06217.7 CDI83707.1 - 4.5 7.1 26.0 5.5 6.8 18.0 1.0 1 0 0 1 1 1 0 GAGA binding protein-like family Cwf_Cwc_15 PF04889.7 CDI83707.1 - 4.9 6.7 27.8 5.9 6.5 19.3 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein PCEMA1 PF07418.6 CDI83707.1 - 5 6.3 9.2 5.8 6.1 6.4 1.1 1 0 0 1 1 1 0 Acidic phosphoprotein precursor PCEMA1 Bunya_G1 PF03557.10 CDI83707.1 - 5.3 4.7 13.6 5.7 4.5 9.4 1.1 1 0 0 1 1 1 0 Bunyavirus glycoprotein G1 PAT1 PF09770.4 CDI83707.1 - 9.2 4.3 69.0 10 4.2 47.8 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF342 PF03961.8 CDI83707.1 - 9.7 4.4 20.9 12 4.2 14.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) TSP_1 PF00090.14 CDI83742.1 - 8.2e-06 25.8 32.2 0.00018 21.5 2.8 5.6 4 0 0 4 4 4 2 Thrombospondin type 1 domain Aconitase PF00330.15 CDI83749.1 - 1.4e-128 429.3 0.0 1.8e-128 428.9 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 CDI83749.1 - 1.3e-41 141.8 0.0 2.2e-41 141.0 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain Nucleoporin_FG PF13634.1 CDI83755.1 - 8.8e-14 51.7 176.2 6.1e-08 32.8 32.5 6.1 1 1 3 4 4 4 2 Nucleoporin FG repeat region Nsp1_C PF05064.8 CDI83755.1 - 2.6e-12 46.3 3.2 2.6e-12 46.3 2.2 2.1 2 1 0 2 2 2 1 Nsp1-like C-terminal region DUF1664 PF07889.7 CDI83755.1 - 0.55 10.0 6.3 5.1 6.9 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Baculo_PEP_C PF04513.7 CDI83755.1 - 1.2 8.9 5.8 0.65 9.8 1.9 1.9 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Pkinase PF00069.20 CDI83756.1 - 7.5e-42 143.2 0.0 9.2e-42 142.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDI83756.1 - 8.8e-24 83.9 0.0 1e-23 83.7 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CDI83756.1 - 2.1e-05 24.3 0.0 0.0065 16.2 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 CDI83756.1 - 0.018 13.8 0.1 0.025 13.3 0.1 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Kinase-like PF14531.1 CDI83756.1 - 0.027 13.4 0.0 1.5 7.7 0.0 2.7 3 0 0 3 3 3 0 Kinase-like ABC1 PF03109.11 CDI83756.1 - 0.036 14.0 0.0 0.11 12.4 0.0 1.8 1 1 1 2 2 2 0 ABC1 family L_protein_N PF15518.1 CDI83756.1 - 0.1 11.9 0.7 0.24 10.7 0.0 1.7 2 0 0 2 2 2 0 L protein N-terminus Etmic-2 PF06670.6 CDI83758.1 - 0.11 11.1 0.0 0.12 11.0 0.0 1.1 1 0 0 1 1 1 0 Microneme protein Etmic-2 Dynamin_M PF01031.15 CDI83763.1 - 3.6e-74 249.2 0.0 5.5e-74 248.6 0.0 1.2 1 0 0 1 1 1 1 Dynamin central region GED PF02212.13 CDI83763.1 - 1.2e-31 108.3 3.1 2.1e-31 107.6 1.1 2.2 2 0 0 2 2 2 1 Dynamin GTPase effector domain Dynamin_N PF00350.18 CDI83764.1 - 1.5e-52 177.8 0.0 1.7e-52 177.6 0.0 1.0 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.18 CDI83764.1 - 3.9e-06 26.7 0.0 9.8e-06 25.5 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 CDI83764.1 - 0.01 16.3 0.0 0.015 15.8 0.0 1.4 1 0 0 1 1 1 0 Miro-like protein GTP_EFTU PF00009.22 CDI83764.1 - 0.012 15.0 0.1 0.084 12.3 0.1 2.0 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain AAA_16 PF13191.1 CDI83764.1 - 0.037 14.0 0.0 0.051 13.5 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain FeoB_N PF02421.13 CDI83764.1 - 0.077 12.2 0.0 1.3 8.2 0.0 2.2 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_28 PF13521.1 CDI83764.1 - 0.083 12.8 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain Phage_tail_X PF05489.7 CDI83764.1 - 0.14 11.6 0.0 1.7 8.1 0.0 2.6 2 0 0 2 2 2 0 Phage Tail Protein X Amino_oxidase PF01593.19 CDI83765.1 - 2.5e-48 165.2 14.8 7.7e-42 143.8 0.1 3.7 4 0 0 4 4 4 2 Flavin containing amine oxidoreductase zf-CW PF07496.10 CDI83765.1 - 3.8e-33 112.9 38.0 2.5e-11 43.1 5.9 3.7 3 0 0 3 3 3 3 CW-type Zinc Finger NAD_binding_8 PF13450.1 CDI83765.1 - 1.5e-07 31.2 7.1 5.3e-07 29.5 1.4 3.3 1 1 1 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 CDI83765.1 - 0.013 14.6 0.3 0.028 13.5 0.2 1.5 1 0 0 1 1 1 0 Thi4 family Pyr_redox_3 PF13738.1 CDI83765.1 - 0.066 13.2 0.1 0.066 13.2 0.1 3.4 3 1 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 CDI83765.1 - 0.28 11.6 1.9 0.37 11.2 0.3 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase rve PF00665.21 CDI83776.1 - 1.6e-16 60.5 0.0 4.4e-16 59.0 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.1 CDI83776.1 - 0.011 15.2 0.2 0.14 11.7 0.1 2.3 2 0 0 2 2 2 0 Integrase core domain RVT_1 PF00078.22 CDI83777.1 - 0.0026 17.1 0.1 0.063 12.6 0.0 2.2 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Folate_carrier PF01770.13 CDI83777.1 - 0.044 12.2 0.1 0.26 9.7 0.1 1.8 2 0 0 2 2 2 0 Reduced folate carrier gag-asp_proteas PF13975.1 CDI83779.1 - 1.4e-07 31.2 0.1 3.2e-07 30.0 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 CDI83779.1 - 0.00011 22.6 0.1 0.00036 20.9 0.0 1.8 2 0 0 2 2 2 1 Aspartyl protease DUF1758 PF05585.7 CDI83779.1 - 0.16 11.5 0.0 0.31 10.5 0.0 1.4 1 0 0 1 1 1 0 Putative peptidase (DUF1758) zf-CCHC PF00098.18 CDI83779.1 - 1.4 8.9 7.9 0.087 12.7 0.4 2.3 2 0 0 2 2 2 0 Zinc knuckle Peptidase_C37 PF05416.7 CDI83781.1 - 0.23 9.7 6.9 0.31 9.3 4.8 1.1 1 0 0 1 1 1 0 Southampton virus-type processing peptidase Hid1 PF12722.2 CDI83781.1 - 5 4.6 5.8 5.4 4.5 4.0 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein EBV-NA3 PF05009.7 CDI83781.1 - 5.2 6.2 6.5 6.3 5.9 4.5 1.2 1 0 0 1 1 1 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) SR-25 PF10500.4 CDI83782.1 - 0.0018 17.7 30.1 0.0018 17.7 20.9 4.1 4 0 0 4 4 4 1 Nuclear RNA-splicing-associated protein CDK2AP PF09806.4 CDI83782.1 - 0.0084 16.3 7.8 0.0084 16.3 5.4 3.8 2 1 1 3 3 3 1 Cyclin-dependent kinase 2-associated protein Ribosomal_S24e PF01282.14 CDI83783.1 - 4.5e-23 80.8 0.0 8.2e-23 80.0 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S24e P120R PF08062.6 CDI83783.1 - 3.4 8.0 7.4 6.3 7.2 0.1 2.8 2 0 0 2 2 2 0 P120R (NUC006) repeat Ribosomal_L1 PF00687.16 CDI83784.1 - 3.5e-34 118.0 6.2 5.5e-28 97.8 0.8 2.0 1 1 1 2 2 2 2 Ribosomal protein L1p/L10e family U3snoRNP10 PF12397.3 CDI83784.1 - 0.057 13.3 0.2 0.19 11.7 0.1 1.8 1 1 0 1 1 1 0 U3 small nucleolar RNA-associated protein 10 PAT1 PF09770.4 CDI83799.1 - 0.003 15.9 67.7 0.0032 15.8 46.9 1.1 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 MIP-T3 PF10243.4 CDI83799.1 - 0.015 13.7 27.4 0.019 13.4 19.0 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Macoilin PF09726.4 CDI83799.1 - 0.031 12.5 24.4 0.035 12.4 16.9 1.0 1 0 0 1 1 1 0 Transmembrane protein DUF4045 PF13254.1 CDI83799.1 - 0.065 12.5 24.7 0.077 12.2 17.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Utp14 PF04615.8 CDI83799.1 - 0.15 10.1 21.4 0.18 9.9 14.8 1.1 1 0 0 1 1 1 0 Utp14 protein Med15 PF09606.5 CDI83799.1 - 0.15 10.2 70.8 0.19 9.8 49.1 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Gag_spuma PF03276.9 CDI83799.1 - 0.38 9.0 41.4 0.46 8.7 28.7 1.2 1 0 0 1 1 1 0 Spumavirus gag protein SRP-alpha_N PF04086.8 CDI83799.1 - 0.55 9.5 24.1 0.75 9.1 16.7 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Neur_chan_memb PF02932.11 CDI83799.1 - 1.3 8.8 19.9 1.7 8.4 13.8 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region SAPS PF04499.10 CDI83799.1 - 1.6 7.2 16.2 2.1 6.8 11.3 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF966 PF06136.8 CDI83799.1 - 1.8 7.8 22.9 2.3 7.5 15.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) SAGA-Tad1 PF12767.2 CDI83799.1 - 3.4 7.2 34.5 4.5 6.8 23.9 1.1 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit SARG PF15385.1 CDI83799.1 - 4.3 6.6 39.6 6 6.1 27.4 1.2 1 0 0 1 1 1 0 Specifically androgen-regulated gene protein FAM176 PF14851.1 CDI83799.1 - 5 6.7 12.5 11 5.6 4.9 2.1 2 0 0 2 2 2 0 FAM176 family DNA_pol_viral_N PF00242.12 CDI83799.1 - 6.2 5.7 25.1 7.4 5.4 17.4 1.1 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain Ycf1 PF05758.7 CDI83799.1 - 6.4 4.3 15.8 7.5 4.1 11.0 1.0 1 0 0 1 1 1 0 Ycf1 DUF4407 PF14362.1 CDI83799.1 - 7.2 5.4 23.4 9.5 5.0 16.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF4557 PF15101.1 CDI83799.1 - 7.3 6.3 39.2 6.9 6.4 17.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4557) Otopetrin PF03189.8 CDI83799.1 - 7.4 5.4 9.5 10 4.9 6.6 1.2 1 0 0 1 1 1 0 Otopetrin PAT1 PF09770.4 CDI83835.1 - 2.8 6.0 76.9 3.5 5.7 53.3 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Herpes_TAF50 PF03326.8 CDI83835.1 - 3.1 6.6 61.2 4 6.2 42.4 1.3 1 0 0 1 1 1 0 Herpesvirus transcription activation factor (transactivator) DUF21 PF01595.15 CDI83843.1 - 0.0063 15.8 0.0 0.013 14.8 0.0 1.4 2 0 0 2 2 2 1 Domain of unknown function DUF21 Spt5_N PF11942.3 CDI83848.1 - 2e-09 37.9 10.2 2e-09 37.9 7.1 3.9 2 2 1 3 3 3 1 Spt5 transcription elongation factor, acidic N-terminal PAS PF00989.19 CDI83848.1 - 0.36 10.6 5.6 0.5 10.1 0.7 2.3 2 0 0 2 2 2 0 PAS fold SOBP PF15279.1 CDI83848.1 - 1.2 9.4 8.1 1.7 8.9 5.6 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein Ctr PF04145.10 CDI83848.1 - 2.1 8.4 7.5 3.9 7.5 1.3 2.3 2 0 0 2 2 2 0 Ctr copper transporter family LMBR1 PF04791.11 CDI83848.1 - 2.2 6.7 9.5 2.5 6.5 6.6 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein MIP-T3 PF10243.4 CDI83848.1 - 2.2 6.6 46.8 2.5 6.4 32.4 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Arv1 PF04161.8 CDI83889.1 - 8.3e-16 58.5 3.0 1.7e-15 57.5 0.1 2.7 2 0 0 2 2 2 1 Arv1-like family OmpH PF03938.9 CDI83889.1 - 0.0019 18.1 25.8 0.0019 18.1 17.9 5.0 2 2 1 3 3 3 1 Outer membrane protein (OmpH-like) CcmD PF04995.9 CDI83889.1 - 0.014 15.0 7.0 0.014 15.0 4.8 6.4 6 1 0 6 6 6 0 Heme exporter protein D (CcmD) TLC PF03219.9 CDI83889.1 - 0.14 10.5 0.0 0.29 9.5 0.0 1.5 1 0 0 1 1 1 0 TLC ATP/ADP transporter SprA-related PF12118.3 CDI83889.1 - 5 6.3 107.7 0.019 14.3 16.7 4.1 4 0 0 4 4 4 0 SprA-related family TFIIF_beta PF02270.10 CDI83933.1 - 0.00058 19.7 0.2 0.00076 19.3 0.1 1.1 1 0 0 1 1 1 1 Transcription initiation factor IIF, beta subunit THOC7 PF05615.8 CDI83933.1 - 0.038 14.2 1.3 0.046 14.0 0.9 1.1 1 0 0 1 1 1 0 Tho complex subunit 7 RPA_C PF08784.6 CDI83933.1 - 0.16 12.3 0.3 0.49 10.8 0.2 1.8 1 1 0 1 1 1 0 Replication protein A C terminal DUF605 PF04652.11 CDI83939.1 - 7.9 5.7 59.0 11 5.2 40.9 1.3 1 0 0 1 1 1 0 Vta1 like CDC45 PF02724.9 CDI83960.1 - 1.1 7.1 37.5 1.8 6.5 26.0 1.3 1 0 0 1 1 1 0 CDC45-like protein Parvo_coat PF00740.13 CDI83960.1 - 2 7.3 38.9 3 6.6 26.9 1.2 1 0 0 1 1 1 0 Parvovirus coat protein VP2 RAP1 PF07218.6 CDI83960.1 - 4.8 5.1 10.4 0.021 12.9 0.9 1.6 2 0 0 2 2 2 0 Rhoptry-associated protein 1 (RAP-1) Transp_cyt_pur PF02133.10 CDI83993.1 - 0.0095 14.5 1.9 0.019 13.5 1.3 1.4 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DUF106 PF01956.11 CDI83993.1 - 0.13 11.7 0.0 0.13 11.7 0.0 6.1 6 1 0 6 6 6 0 Integral membrane protein DUF106 IncA PF04156.9 CDI83994.1 - 0.0036 16.9 2.9 0.0036 16.9 2.0 4.7 2 2 1 3 3 3 1 IncA protein DUF1467 PF07330.7 CDI83994.1 - 0.051 13.3 1.5 0.3 10.8 1.0 2.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1467) Ebola_NP PF05505.7 CDI83994.1 - 0.44 8.5 36.5 0.16 10.0 12.0 2.4 2 0 0 2 2 2 0 Ebola nucleoprotein Peptidase_C37 PF05416.7 CDI83995.1 - 0.66 8.2 12.1 0.79 7.9 8.4 1.1 1 0 0 1 1 1 0 Southampton virus-type processing peptidase Zip PF02535.17 CDI83995.1 - 0.76 8.7 7.9 1.1 8.1 5.5 1.3 1 1 0 1 1 1 0 ZIP Zinc transporter DUF1510 PF07423.6 CDI83995.1 - 3.6 6.8 24.9 3.1 7.0 9.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) DUF3449 PF11931.3 CDI83995.1 - 6.1 6.3 23.2 5 6.5 8.9 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3449) RE_TdeIII PF09520.5 CDI83995.1 - 6.7 5.9 18.8 7 5.8 13.0 1.0 1 0 0 1 1 1 0 Type II restriction endonuclease, TdeIII ATP-synt_G PF04718.10 CDI84000.1 - 0.73 10.5 3.0 0.52 11.0 0.3 1.9 2 0 0 2 2 2 0 Mitochondrial ATP synthase g subunit TFIIA PF03153.8 CDI84000.1 - 8.7 6.1 21.7 10 5.9 15.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CAP_N PF01213.14 CDI84000.1 - 9.7 5.3 13.5 20 4.3 0.0 2.2 1 1 1 2 2 2 0 Adenylate cyclase associated (CAP) N terminal Potyvirid-P3 PF13608.1 CDI84005.1 - 8.1e-05 21.9 5.8 8.1e-05 21.9 4.0 2.2 1 1 1 2 2 2 1 Protein P3 of Potyviral polyprotein IncA PF04156.9 CDI84005.1 - 0.00051 19.6 24.2 0.00051 19.6 16.8 4.2 4 1 0 4 4 4 1 IncA protein Dymeclin PF09742.4 CDI84005.1 - 0.012 13.7 10.5 0.014 13.5 7.3 1.1 1 0 0 1 1 1 0 Dyggve-Melchior-Clausen syndrome protein WES_acyltransf PF03007.11 CDI84005.1 - 0.012 15.1 2.7 0.012 15.1 1.9 3.9 1 1 3 4 4 4 0 Wax ester synthase-like Acyl-CoA acyltransferase domain N6_N4_Mtase PF01555.13 CDI84005.1 - 0.019 14.4 0.0 0.098 12.1 0.0 2.2 1 1 0 1 1 1 0 DNA methylase E1-N PF14463.1 CDI84005.1 - 0.045 13.3 0.7 0.045 13.3 0.5 4.2 3 1 1 4 4 4 0 E1 N-terminal domain DUF3357 PF11837.3 CDI84005.1 - 0.069 12.9 0.1 0.069 12.9 0.1 4.7 3 1 1 4 4 4 0 Domain of unknown function (DUF3357) eIF-3_zeta PF05091.7 CDI84005.1 - 2 6.9 41.5 0.098 11.2 15.0 2.3 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) FPN1 PF06963.7 CDI84005.1 - 5.4 5.2 25.8 0.65 8.3 0.2 3.4 2 1 0 2 2 2 0 Ferroportin1 (FPN1) LMBR1 PF04791.11 CDI84005.1 - 9.6 4.6 13.1 19 3.6 9.1 1.7 1 1 0 1 1 1 0 LMBR1-like membrane protein PAS_5 PF07310.8 CDI84022.1 - 1.4 8.4 7.7 3.9 7.0 0.1 2.5 3 0 0 3 3 3 0 PAS domain SR-25 PF10500.4 CDI84039.1 - 0.00015 21.3 45.9 0.006 16.0 4.2 3.2 3 0 0 3 3 3 2 Nuclear RNA-splicing-associated protein SseC PF04888.7 CDI84039.1 - 0.005 16.2 46.0 0.005 16.2 31.9 3.2 3 0 0 3 3 3 1 Secretion system effector C (SseC) like family Plasmodium_Vir PF05795.6 CDI84039.1 - 0.88 8.7 12.5 0.061 12.5 2.8 2.3 1 1 1 2 2 2 0 Plasmodium vivax Vir protein DUF2052 PF09747.4 CDI84039.1 - 3 7.7 31.4 4.3 7.2 2.1 2.2 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) Ycf1 PF05758.7 CDI84039.1 - 5.5 4.5 23.3 0.82 7.2 8.1 2.0 2 0 0 2 2 2 0 Ycf1 AAA_5 PF07728.9 CDI84057.1 - 3e-68 227.8 0.0 1.1e-20 73.7 0.0 8.3 7 1 1 8 8 8 7 AAA domain (dynein-related subfamily) AAA PF00004.24 CDI84057.1 - 9.5e-11 42.0 0.1 0.013 15.6 0.0 4.5 4 0 0 4 4 3 3 ATPase family associated with various cellular activities (AAA) UPF0079 PF02367.12 CDI84057.1 - 5.4e-07 29.2 0.7 0.24 11.0 0.0 3.6 3 0 0 3 3 3 2 Uncharacterised P-loop hydrolase UPF0079 AAA_17 PF13207.1 CDI84057.1 - 1.9e-06 28.6 0.0 0.34 11.7 0.0 3.9 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.1 CDI84057.1 - 3.3e-06 27.2 42.8 0.01 15.8 0.0 8.1 6 1 0 6 6 6 3 AAA ATPase domain AAA_14 PF13173.1 CDI84057.1 - 2.2e-05 24.3 0.0 0.0048 16.7 0.0 4.2 4 0 0 4 4 3 1 AAA domain Phage_1_1 PF08200.6 CDI84057.1 - 2.9e-05 24.1 13.0 0.061 13.5 1.9 3.9 2 0 0 2 2 2 2 Bacteriophage 1.1 Protein AAA_18 PF13238.1 CDI84057.1 - 5e-05 23.6 0.0 3.9 7.7 0.0 4.9 4 0 0 4 4 4 2 AAA domain RNA_helicase PF00910.17 CDI84057.1 - 0.0004 20.5 0.0 11 6.2 0.0 3.5 3 0 0 3 3 3 0 RNA helicase ABC_tran PF00005.22 CDI84057.1 - 0.00062 20.0 15.1 0.028 14.7 0.0 5.6 5 0 0 5 5 4 2 ABC transporter AAA_29 PF13555.1 CDI84057.1 - 0.0011 18.4 0.0 1.5 8.3 0.0 3.7 3 0 0 3 3 3 1 P-loop containing region of AAA domain PduV-EutP PF10662.4 CDI84057.1 - 0.011 15.1 0.2 4.6 6.7 0.1 3.4 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation MobB PF03205.9 CDI84057.1 - 0.012 15.3 0.0 5 6.8 0.0 3.3 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B Mem_trans PF03547.13 CDI84057.1 - 0.14 10.4 4.0 2.8 6.1 0.0 2.4 2 0 0 2 2 2 0 Membrane transport protein Asp_protease_2 PF13650.1 CDI84057.1 - 0.19 12.2 0.0 7.7 7.1 0.0 2.7 2 0 0 2 2 2 0 Aspartyl protease AAA_23 PF13476.1 CDI84057.1 - 0.46 10.7 0.0 0.46 10.7 0.0 8.4 9 0 0 9 9 9 0 AAA domain AAA_22 PF13401.1 CDI84057.1 - 0.57 10.3 0.0 0.57 10.3 0.0 6.3 7 1 0 7 7 5 0 AAA domain Miro PF08477.8 CDI84057.1 - 5.1 7.6 13.0 23 5.5 0.0 4.8 5 0 0 5 5 3 0 Miro-like protein NDK PF00334.14 CDI84058.1 - 9.3e-18 64.3 0.0 8.2e-15 54.7 0.0 2.4 2 0 0 2 2 2 2 Nucleoside diphosphate kinase Rib PF08428.5 CDI84058.1 - 0.16 11.7 0.0 18 5.1 0.0 2.3 2 0 0 2 2 2 0 Rib/alpha-like repeat Fe-S_biosyn PF01521.15 CDI84059.1 - 1.7e-06 27.8 0.1 0.00066 19.6 0.0 2.6 2 1 0 2 2 2 2 Iron-sulphur cluster biosynthesis STAS_2 PF13466.1 CDI84059.1 - 0.072 13.1 0.7 0.19 11.8 0.5 1.6 1 0 0 1 1 1 0 STAS domain Amino_oxidase PF01593.19 CDI84064.1 - 1.3 7.9 12.1 1.8 7.5 8.4 1.2 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase AF-4 PF05110.8 CDI84065.1 - 0.00064 17.7 35.8 0.00085 17.3 24.8 1.1 1 0 0 1 1 1 1 AF-4 proto-oncoprotein DUF4207 PF13904.1 CDI84065.1 - 0.0016 17.9 48.7 0.0023 17.3 33.7 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4207) DUF605 PF04652.11 CDI84065.1 - 0.012 15.0 34.7 0.015 14.6 24.1 1.2 1 0 0 1 1 1 0 Vta1 like Ribosomal_60s PF00428.14 CDI84065.1 - 0.013 15.8 9.2 0.028 14.8 6.4 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein CAF-1_p150 PF11600.3 CDI84065.1 - 0.027 13.8 50.0 0.0085 15.4 32.9 1.4 1 1 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal SOBP PF15279.1 CDI84065.1 - 0.05 13.9 35.1 0.062 13.6 24.3 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein Raftlin PF15250.1 CDI84065.1 - 0.064 11.7 22.8 0.096 11.1 15.8 1.3 1 0 0 1 1 1 0 Raftlin TFIIA PF03153.8 CDI84065.1 - 1.4 8.7 51.9 2.1 8.1 36.0 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Ycf1 PF05758.7 CDI84065.1 - 2.2 5.8 24.0 2.6 5.6 16.6 1.2 1 0 0 1 1 1 0 Ycf1 Utp14 PF04615.8 CDI84065.1 - 2.3 6.2 38.0 2.8 5.9 26.4 1.1 1 0 0 1 1 1 0 Utp14 protein DUF342 PF03961.8 CDI84065.1 - 3.5 5.9 18.2 4.6 5.5 12.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF4175 PF13779.1 CDI84065.1 - 5.7 4.5 54.9 7.1 4.1 38.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) PAT1 PF09770.4 CDI84065.1 - 6.3 4.8 56.2 8.7 4.4 39.0 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Peptidase_S64 PF08192.6 CDI84065.1 - 7.5 4.7 30.7 9.4 4.4 21.3 1.2 1 0 0 1 1 1 0 Peptidase family S64 Draxin PF15550.1 CDI84065.1 - 7.8 6.0 26.8 11 5.5 18.6 1.2 1 0 0 1 1 1 0 Draxin DUF4551 PF15087.1 CDI84065.1 - 8.4 4.6 30.4 9.7 4.4 21.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) AvrE PF11725.3 CDI84065.1 - 9.3 3.1 35.2 11 2.8 24.4 1.0 1 0 0 1 1 1 0 Pathogenicity factor ERF PF04404.7 CDI84069.1 - 0.034 13.6 13.3 0.045 13.2 9.2 1.2 1 0 0 1 1 1 0 ERF superfamily MlrC_C PF07171.7 CDI84069.1 - 0.051 13.1 0.1 0.052 13.1 0.1 1.1 1 0 0 1 1 1 0 MlrC C-terminus Nop53 PF07767.6 CDI84069.1 - 0.062 12.2 16.3 0.065 12.2 11.3 1.0 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) tRNA_synt_1c_R2 PF04557.10 CDI84069.1 - 0.082 13.6 9.3 0.12 13.0 6.4 1.3 1 0 0 1 1 1 0 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 Bac_luciferase PF00296.15 CDI84069.1 - 0.17 10.9 3.2 0.17 10.9 2.2 1.0 1 0 0 1 1 1 0 Luciferase-like monooxygenase PTA_PTB PF01515.14 CDI84069.1 - 0.2 10.6 3.6 0.21 10.5 2.5 1.0 1 0 0 1 1 1 0 Phosphate acetyl/butaryl transferase U79_P34 PF03064.11 CDI84069.1 - 0.21 11.0 9.5 0.23 10.9 6.6 1.0 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Glt_symporter PF03616.9 CDI84069.1 - 0.26 9.7 1.5 0.27 9.6 1.0 1.0 1 0 0 1 1 1 0 Sodium/glutamate symporter FimP PF09766.4 CDI84069.1 - 0.35 9.8 16.1 0.35 9.8 11.1 1.0 1 0 0 1 1 1 0 Fms-interacting protein TMEM51 PF15345.1 CDI84069.1 - 0.39 10.3 8.4 0.39 10.3 5.8 1.1 1 0 0 1 1 1 0 Transmembrane protein 51 IncA PF04156.9 CDI84069.1 - 0.52 9.8 12.5 0.53 9.8 8.6 1.1 1 0 0 1 1 1 0 IncA protein YjeF_N PF03853.10 CDI84069.1 - 0.73 9.4 5.1 0.83 9.2 3.6 1.0 1 0 0 1 1 1 0 YjeF-related protein N-terminus Mem_trans PF03547.13 CDI84069.1 - 0.73 8.0 2.4 0.77 7.9 1.7 1.0 1 0 0 1 1 1 0 Membrane transport protein NARP1 PF12569.3 CDI84069.1 - 0.93 8.1 12.7 0.9 8.2 8.8 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 FLO_LFY PF01698.11 CDI84069.1 - 0.94 8.2 11.7 0.99 8.1 8.1 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein SprA-related PF12118.3 CDI84069.1 - 1.1 8.5 23.4 1.2 8.3 16.2 1.1 1 0 0 1 1 1 0 SprA-related family DUF912 PF06024.7 CDI84069.1 - 1.3 9.1 7.4 1.4 8.9 5.1 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) RR_TM4-6 PF06459.7 CDI84069.1 - 1.5 8.6 9.5 1.3 8.8 6.6 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 FAM176 PF14851.1 CDI84069.1 - 1.6 8.4 6.8 1.8 8.2 4.7 1.1 1 0 0 1 1 1 0 FAM176 family Suf PF05843.9 CDI84069.1 - 1.7 8.3 11.4 1.6 8.4 7.9 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DDHD PF02862.12 CDI84069.1 - 1.8 8.3 7.2 1.7 8.4 5.0 1.1 1 0 0 1 1 1 0 DDHD domain CagX PF03524.10 CDI84069.1 - 2.1 7.5 7.3 2.2 7.4 5.1 1.2 1 0 0 1 1 1 0 Conjugal transfer protein FHIPEP PF00771.15 CDI84069.1 - 2.2 6.4 6.5 2.1 6.6 4.5 1.0 1 0 0 1 1 1 0 FHIPEP family DUF4175 PF13779.1 CDI84069.1 - 2.4 5.7 23.9 2.2 5.8 16.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Dala_Dala_lig_N PF01820.16 CDI84069.1 - 2.6 8.4 5.6 2.8 8.2 3.9 1.1 1 0 0 1 1 1 0 D-ala D-ala ligase N-terminus Peptidase_S49_N PF08496.5 CDI84069.1 - 2.7 7.7 13.1 2.9 7.6 9.1 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF1071 PF06378.6 CDI84069.1 - 2.7 7.0 8.9 2.6 7.1 6.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1071) DUF3464 PF11947.3 CDI84069.1 - 3 7.2 8.1 2.9 7.3 5.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) zf-DHHC PF01529.15 CDI84069.1 - 3.5 6.9 5.1 3.4 7.0 3.5 1.1 1 0 0 1 1 1 0 DHHC palmitoyltransferase Serinc PF03348.10 CDI84069.1 - 3.5 6.2 8.8 3.2 6.3 6.1 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) AIF_C PF14721.1 CDI84069.1 - 3.7 7.8 7.3 3.6 7.8 5.1 1.1 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Pal1 PF08316.6 CDI84069.1 - 3.8 7.9 5.8 3.8 7.9 4.0 1.0 1 0 0 1 1 1 0 Pal1 cell morphology protein Band_3_cyto PF07565.8 CDI84069.1 - 3.8 6.9 7.9 3.6 7.0 5.5 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain RabGAP-TBC PF00566.13 CDI84069.1 - 3.9 6.8 10.4 4.3 6.7 7.2 1.1 1 0 0 1 1 1 0 Rab-GTPase-TBC domain DUF4557 PF15101.1 CDI84069.1 - 4.1 7.1 15.7 3.8 7.2 10.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) AAA_23 PF13476.1 CDI84069.1 - 4.6 7.5 14.6 4.1 7.6 10.1 1.0 1 0 0 1 1 1 0 AAA domain eIF_4EBP PF05456.6 CDI84069.1 - 4.7 6.9 7.9 5.1 6.8 5.5 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) Gag_spuma PF03276.9 CDI84069.1 - 5 5.3 16.7 4.7 5.4 11.6 1.0 1 0 0 1 1 1 0 Spumavirus gag protein PEX11 PF05648.9 CDI84069.1 - 5.1 6.2 6.8 5.2 6.2 4.7 1.1 1 0 0 1 1 1 0 Peroxisomal biogenesis factor 11 (PEX11) DUF1980 PF09323.5 CDI84069.1 - 5.8 6.6 8.5 5.6 6.6 5.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) Oleosin PF01277.12 CDI84069.1 - 8.2 6.0 6.2 9.8 5.7 4.3 1.2 1 0 0 1 1 1 0 Oleosin PBP_sp32 PF07222.7 CDI84069.1 - 8.8 5.4 15.7 8.3 5.5 10.9 1.1 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Folate_carrier PF01770.13 CDI84069.1 - 9.7 4.5 6.2 9.1 4.6 4.3 1.1 1 0 0 1 1 1 0 Reduced folate carrier DUF3959 PF13105.1 CDI84069.1 - 9.7 5.4 9.7 11 5.2 6.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3959) DUF755 PF05501.6 CDI84080.1 - 0.43 10.6 17.1 0.19 11.7 10.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF755) TFIIA PF03153.8 CDI84080.1 - 8.4 6.1 14.2 11 5.8 9.8 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Shadoo PF14999.1 CDI84087.1 - 0.36 10.6 8.3 0.5 10.2 5.7 1.3 1 0 0 1 1 1 0 Shadow of prion protein, neuroprotective Ribosomal_60s PF00428.14 CDI84087.1 - 0.64 10.4 12.2 1 9.7 8.4 1.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein HAUS6_N PF14661.1 CDI84087.1 - 0.83 8.9 7.4 0.89 8.8 5.2 1.0 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus HSP90 PF00183.13 CDI84093.1 - 1.8e-37 128.9 1.0 4.2e-29 101.3 0.0 2.1 1 1 1 2 2 2 2 Hsp90 protein Ribosomal_60s PF00428.14 CDI84093.1 - 0.013 15.8 1.0 0.56 10.6 2.3 2.1 2 0 0 2 2 2 0 60s Acidic ribosomal protein Ctr PF04145.10 CDI84093.1 - 0.018 15.0 2.3 0.019 15.0 0.2 1.9 2 0 0 2 2 2 0 Ctr copper transporter family HATPase_c_3 PF13589.1 CDI84093.1 - 0.03 13.9 0.0 0.055 13.1 0.0 1.5 1 1 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase LRAT PF04970.8 CDI84093.1 - 0.093 12.6 0.1 0.26 11.2 0.0 1.7 2 0 0 2 2 2 0 Lecithin retinol acyltransferase TFIIA PF03153.8 CDI84093.1 - 0.44 10.3 11.2 0.68 9.7 7.8 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit GTF2I PF02946.9 CDI84102.1 - 0.12 12.2 0.0 1.5 8.6 0.0 2.4 2 0 0 2 2 2 0 GTF2I-like repeat RNase_HII PF01351.13 CDI84118.1 - 0.042 13.4 1.1 0.094 12.3 0.8 1.6 1 0 0 1 1 1 0 Ribonuclease HII SOBP PF15279.1 CDI84118.1 - 0.28 11.5 25.5 0.38 11.0 17.7 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein PAT1 PF09770.4 CDI84118.1 - 0.45 8.6 64.1 0.56 8.3 44.5 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Ofd1_CTDD PF10637.4 CDI84118.1 - 4.7 6.2 13.5 7.9 5.5 9.4 1.3 1 0 0 1 1 1 0 Oxoglutarate and iron-dependent oxygenase degradation C-term Suf PF05843.9 CDI84122.1 - 0.06 13.0 9.1 0.099 12.3 0.5 2.3 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) DUF3499 PF12005.3 CDI84122.1 - 0.46 10.6 5.2 1.1 9.4 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3499) DUF3446 PF11928.3 CDI84122.1 - 10 6.4 41.5 0.37 11.0 5.2 3.8 3 1 0 3 3 3 0 Domain of unknown function (DUF3446) Med15 PF09606.5 CDI84134.1 - 4.1e-05 22.0 85.3 4.1e-05 22.0 59.1 2.5 2 1 0 2 2 2 1 ARC105 or Med15 subunit of Mediator complex non-fungal Macoilin PF09726.4 CDI84134.1 - 0.032 12.5 85.8 0.0032 15.8 36.9 2.1 1 1 1 2 2 2 0 Transmembrane protein PAT1 PF09770.4 CDI84134.1 - 3.1 5.9 110.5 0.23 9.6 53.7 2.1 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 Utp14 PF04615.8 CDI84134.1 - 3.9 5.5 70.8 0.66 8.0 39.2 2.2 2 0 0 2 2 2 0 Utp14 protein Transposase_22 PF02994.9 CDI84139.1 - 0.0076 14.7 12.3 0.0093 14.4 8.5 1.1 1 0 0 1 1 1 1 L1 transposable element DUF2967 PF11179.3 CDI84139.1 - 0.04 13.4 0.5 0.04 13.4 0.4 3.5 1 1 3 4 4 3 0 Protein of unknown function (DUF2967) Pox_Ag35 PF03286.9 CDI84139.1 - 0.55 9.7 16.2 0.62 9.5 10.9 1.5 1 1 0 1 1 1 0 Pox virus Ag35 surface protein Otopetrin PF03189.8 CDI84139.1 - 0.68 8.8 5.2 0.76 8.7 3.6 1.3 1 0 0 1 1 1 0 Otopetrin Ycf1 PF05758.7 CDI84139.1 - 0.85 7.2 15.2 0.93 7.1 10.5 1.1 1 0 0 1 1 1 0 Ycf1 Glyco_transf_15 PF01793.11 CDI84139.1 - 1.6 7.6 11.4 2.9 6.7 7.9 1.6 1 0 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase Suc_Fer-like PF06999.7 CDI84139.1 - 3 7.7 9.3 2.8 7.8 5.6 1.5 1 1 0 1 1 1 0 Sucrase/ferredoxin-like Prog_receptor PF02161.10 CDI84139.1 - 3.2 6.4 21.0 0.2 10.4 11.1 1.4 2 0 0 2 2 2 0 Progesterone receptor Herpes_DNAp_acc PF04929.7 CDI84139.1 - 3.5 6.5 12.0 5.4 5.8 8.3 1.3 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Hid1 PF12722.2 CDI84139.1 - 3.5 5.1 20.1 4.1 4.9 13.9 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SID-1_RNA_chan PF13965.1 CDI84139.1 - 4.5 5.3 6.6 5.5 5.0 4.6 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 TMEM51 PF15345.1 CDI84139.1 - 6.3 6.4 21.2 29 4.2 14.7 2.2 1 1 0 1 1 1 0 Transmembrane protein 51 RNase_H2-Ydr279 PF09468.5 CDI84139.1 - 6.8 5.7 11.9 12 4.9 8.2 1.4 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) Folate_carrier PF01770.13 CDI84139.1 - 9.8 4.5 7.4 15 3.9 5.1 1.4 1 0 0 1 1 1 0 Reduced folate carrier Nucleos_tra2_C PF07662.8 CDI84145.1 - 4.8 6.6 5.9 5 6.5 0.4 4.1 2 0 0 2 2 2 0 Na+ dependent nucleoside transporter C-terminus Spt20 PF12090.3 CDI84157.1 - 0.03 13.6 2.6 0.032 13.5 1.8 1.1 1 0 0 1 1 1 0 Spt20 family DUF3313 PF11769.3 CDI84157.1 - 0.08 12.3 3.8 0.1 11.9 2.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3313) CpXC PF14353.1 CDI84157.1 - 0.76 9.7 4.0 1 9.3 2.8 1.1 1 0 0 1 1 1 0 CpXC protein RED_N PF07808.8 CDI84157.1 - 1 8.5 7.7 1.2 8.3 5.4 1.1 1 0 0 1 1 1 0 RED-like protein N-terminal region PAT1 PF09770.4 CDI84157.1 - 1.1 7.4 18.0 1.1 7.3 12.5 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Suf PF05843.9 CDI84157.1 - 1.1 8.9 7.0 1.2 8.7 4.9 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) TraV PF09676.5 CDI84157.1 - 1.2 9.7 5.0 2.3 8.9 3.5 1.5 1 1 0 1 1 1 0 Type IV conjugative transfer system lipoprotein (TraV) LCD1 PF09798.4 CDI84157.1 - 1.3 6.9 6.3 1.2 6.9 4.4 1.0 1 0 0 1 1 1 0 DNA damage checkpoint protein Pex14_N PF04695.8 CDI84157.1 - 3.2 7.8 12.4 0.048 13.7 3.8 1.4 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF637 PF04830.8 CDI84157.1 - 5.4 6.6 20.5 8.8 5.9 14.2 1.4 1 1 0 1 1 1 0 Possible hemagglutinin (DUF637) DUF4557 PF15101.1 CDI84157.1 - 6.9 6.4 10.1 8.2 6.1 7.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) DUF4231 PF14015.1 CDI84157.1 - 9.9 6.1 10.6 8.1 6.4 6.7 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF4231) Cpn60_TCP1 PF00118.19 CDI84169.1 - 8.1e-21 74.1 1.0 4.5e-10 38.7 0.1 2.2 2 0 0 2 2 2 2 TCP-1/cpn60 chaperonin family Glyco_tran_WecB PF03808.8 CDI84169.1 - 0.022 14.1 2.9 0.058 12.8 2.0 1.6 1 1 1 2 2 2 0 Glycosyl transferase WecB/TagA/CpsF family PRTase_1 PF11202.3 CDI84169.1 - 0.049 12.6 0.2 0.057 12.3 0.1 1.2 1 0 0 1 1 1 0 Phosphoribosyl transferase (PRTase) CDK2AP PF09806.4 CDI84169.1 - 0.078 13.2 4.8 0.087 13.0 3.3 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein DUF1846 PF08903.6 CDI84169.1 - 0.13 10.6 0.3 0.13 10.6 0.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1846) Ribosomal_60s PF00428.14 CDI84169.1 - 0.35 11.2 9.6 0.71 10.3 6.7 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein Gly_rich_SFCGS PF14272.1 CDI84169.1 - 0.47 10.3 6.1 0.87 9.4 1.5 2.1 1 1 1 2 2 2 0 Glycine-rich SFCGS TSA PF03249.8 CDI84169.1 - 3.6 6.0 11.8 4.3 5.7 8.2 1.1 1 0 0 1 1 1 0 Type specific antigen DUF3138 PF11336.3 CDI84169.1 - 9.2 4.3 10.3 9.7 4.2 7.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) MIP-T3 PF10243.4 CDI84173.1 - 0.49 8.8 55.2 0.57 8.5 38.3 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Med15 PF09606.5 CDI84173.1 - 1.6 6.8 116.7 1.9 6.5 80.9 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Asp-B-Hydro_N PF05279.6 CDI84173.1 - 6.8 6.4 40.6 7.8 6.2 28.1 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region PAT1 PF09770.4 CDI84173.1 - 7.4 4.6 101.1 8.1 4.5 70.0 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF3040 PF11239.3 CDI84192.1 - 2.5 8.1 8.5 7.6 6.6 1.8 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) RskA PF10099.4 CDI84196.1 - 0.0019 17.9 15.9 0.0019 17.9 11.0 3.2 1 1 2 3 3 3 1 Anti-sigma-K factor rskA DUF1510 PF07423.6 CDI84196.1 - 0.003 16.9 17.4 0.003 16.9 12.0 2.7 2 1 0 2 2 2 1 Protein of unknown function (DUF1510) ETRAMP PF09716.5 CDI84196.1 - 0.043 13.7 8.2 0.44 10.5 0.9 3.6 2 2 1 3 3 3 0 Malarial early transcribed membrane protein (ETRAMP) Ni_hydr_CYTB PF01292.15 CDI84196.1 - 0.23 10.8 2.2 11 5.3 1.1 2.8 1 1 0 2 2 2 0 Prokaryotic cytochrome b561 Herpes_UL87 PF03043.9 CDI84196.1 - 1.1 7.6 25.9 1.5 7.1 17.9 1.2 1 0 0 1 1 1 0 Herpesvirus UL87 family Toxin_28 PF08115.6 CDI84196.1 - 1.1 8.9 3.4 1.8 8.3 2.4 1.2 1 0 0 1 1 1 0 SFI toxin family TRAP_alpha PF03896.11 CDI84196.1 - 1.2 8.1 9.5 0.16 10.9 2.2 2.1 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit DUF3357 PF11837.3 CDI84196.1 - 1.9 8.3 21.1 1 9.2 1.5 3.9 2 1 1 3 3 3 0 Domain of unknown function (DUF3357) Mem_trans PF03547.13 CDI84196.1 - 2.9 6.1 19.1 1.5 6.9 6.6 2.1 2 0 0 2 2 2 0 Membrane transport protein Ribosomal_60s PF00428.14 CDI84196.1 - 3.8 7.9 8.3 11 6.5 5.8 1.7 1 0 0 1 1 1 0 60s Acidic ribosomal protein DUF4220 PF13968.1 CDI84196.1 - 6.4 5.7 22.9 0.36 9.8 0.8 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4220) Spt20 PF12090.3 CDI84197.1 - 6.3e-05 22.3 14.7 0.11 11.8 1.1 3.5 3 0 0 3 3 3 3 Spt20 family zf-DHHC PF01529.15 CDI84197.1 - 0.016 14.6 1.1 3.2 7.1 0.1 3.1 3 0 0 3 3 3 0 DHHC palmitoyltransferase AAA_23 PF13476.1 CDI84197.1 - 0.048 13.9 11.9 0.46 10.7 1.1 3.2 3 0 0 3 3 3 0 AAA domain EphA2_TM PF14575.1 CDI84197.1 - 0.079 13.3 6.2 2.5 8.5 0.2 3.8 3 0 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain FimP PF09766.4 CDI84197.1 - 0.092 11.8 30.0 0.078 12.0 4.5 3.2 3 0 0 3 3 3 0 Fms-interacting protein FHIPEP PF00771.15 CDI84197.1 - 1.2 7.3 16.3 0.052 11.8 0.6 3.2 3 0 0 3 3 3 0 FHIPEP family DivIC PF04977.10 CDI84197.1 - 1.7 8.1 35.6 0.21 11.0 3.1 3.7 3 0 0 3 3 3 0 Septum formation initiator Suf PF05843.9 CDI84197.1 - 3 7.4 34.8 0.051 13.3 2.8 3.7 3 1 0 3 3 3 0 Suppressor of forked protein (Suf) Na_trans_assoc PF06512.8 CDI84197.1 - 3.9 7.3 18.7 0.19 11.6 0.5 4.4 4 0 0 4 4 4 0 Sodium ion transport-associated PH_4 PF15404.1 CDI84197.1 - 6.6 6.2 12.8 5 6.6 1.3 3.5 3 0 0 3 3 3 0 Pleckstrin homology domain DUF812 PF05667.6 CDI84208.1 - 0.00026 19.6 1.5 0.00026 19.6 1.1 3.0 2 1 1 3 3 3 1 Protein of unknown function (DUF812) AAA_23 PF13476.1 CDI84208.1 - 3.9 7.7 39.0 1.8 8.8 0.3 3.3 3 0 0 3 3 3 0 AAA domain BPD_transp_2 PF02653.11 CDI84222.1 - 0.0056 15.6 1.6 0.0056 15.6 1.1 2.1 1 1 1 2 2 2 1 Branched-chain amino acid transport system / permease component Pox_P21 PF05313.7 CDI84222.1 - 0.23 10.6 2.2 0.28 10.4 0.2 1.8 1 1 1 2 2 2 0 Poxvirus P21 membrane protein IncA PF04156.9 CDI84222.1 - 4.2 6.9 16.4 0.27 10.8 4.8 2.3 2 0 0 2 2 2 0 IncA protein Med15 PF09606.5 CDI84229.1 - 0.00023 19.5 53.4 0.00039 18.7 37.0 1.3 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal Suf PF05843.9 CDI84229.1 - 0.0045 16.7 20.6 0.02 14.6 8.7 2.2 2 0 0 2 2 2 2 Suppressor of forked protein (Suf) AAA_23 PF13476.1 CDI84229.1 - 0.013 15.8 2.0 0.013 15.8 1.4 2.1 2 0 0 2 2 2 0 AAA domain DUF4276 PF14103.1 CDI84229.1 - 0.032 14.1 1.3 0.032 14.1 0.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4276) FimP PF09766.4 CDI84229.1 - 0.034 13.2 26.2 0.15 11.1 12.9 2.1 2 0 0 2 2 2 0 Fms-interacting protein GOLD_2 PF13897.1 CDI84229.1 - 0.037 14.2 0.2 0.18 12.0 0.0 2.1 2 0 0 2 2 2 0 Golgi-dynamics membrane-trafficking eIF-3_zeta PF05091.7 CDI84229.1 - 0.078 11.5 14.3 0.046 12.3 3.8 2.1 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Dala_Dala_lig_N PF01820.16 CDI84229.1 - 0.2 12.0 4.3 0.77 10.0 0.7 2.3 2 0 0 2 2 2 0 D-ala D-ala ligase N-terminus eIF3g PF12353.3 CDI84229.1 - 0.23 11.3 11.2 1.1 9.1 4.8 2.5 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit G RR_TM4-6 PF06459.7 CDI84229.1 - 0.35 10.7 9.3 0.12 12.2 2.3 2.2 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 DUF2126 PF09899.4 CDI84229.1 - 0.43 8.5 8.0 0.053 11.5 2.2 1.7 2 0 0 2 2 2 0 Putative amidoligase enzyme (DUF2126) Peptidase_S49_N PF08496.5 CDI84229.1 - 0.59 9.9 10.6 5.4 6.8 4.6 2.2 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Ribosomal_L6e PF01159.14 CDI84229.1 - 0.76 10.0 8.7 0.56 10.4 2.0 2.2 2 0 0 2 2 2 0 Ribosomal protein L6e DUF1764 PF08576.5 CDI84229.1 - 0.95 10.2 16.6 6.7 7.5 6.8 2.6 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF1764) DUF2029 PF09594.5 CDI84229.1 - 0.97 8.8 22.0 14 5.1 15.3 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF2029) RED_N PF07808.8 CDI84229.1 - 1.1 8.4 24.8 0.64 9.1 0.1 2.3 2 0 0 2 2 2 0 RED-like protein N-terminal region CPSF100_C PF13299.1 CDI84229.1 - 1.3 9.1 8.2 2.1 8.5 3.4 2.3 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal DUF3801 PF12687.2 CDI84229.1 - 1.4 8.4 17.9 0.1 12.1 5.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3801) Serinc PF03348.10 CDI84229.1 - 1.6 7.3 12.9 2.4 6.7 5.3 2.1 2 0 0 2 2 2 0 Serine incorporator (Serinc) DUF4647 PF15504.1 CDI84229.1 - 1.7 7.3 18.3 0.35 9.6 4.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4647) DUF912 PF06024.7 CDI84229.1 - 1.9 8.5 12.6 0.68 10.0 4.4 2.6 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Raftlin PF15250.1 CDI84229.1 - 1.9 6.8 13.0 0.93 7.9 6.5 1.9 2 0 0 2 2 2 0 Raftlin XRCC4 PF06632.7 CDI84229.1 - 2.1 7.1 14.0 1.9 7.2 7.5 2.0 2 0 0 2 2 2 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 CD20 PF04103.10 CDI84229.1 - 2.4 8.0 6.1 13 5.7 2.3 2.7 2 0 0 2 2 2 0 CD20-like family Baculo_PP31 PF05311.6 CDI84229.1 - 3.2 6.9 13.2 2.2 7.4 5.7 2.1 2 0 0 2 2 2 0 Baculovirus 33KDa late protein (PP31) SeqA PF03925.8 CDI84229.1 - 3.2 7.4 10.7 3.5 7.2 4.6 2.1 2 0 0 2 2 2 0 SeqA protein DUF3675 PF12428.3 CDI84229.1 - 3.8 7.8 9.4 0.51 10.6 1.3 2.7 3 0 0 3 3 2 0 Protein of unknown function (DUF3675) Peptidase_M17_N PF02789.12 CDI84229.1 - 4.2 7.1 14.1 12 5.6 0.1 2.3 2 0 0 2 2 2 0 Cytosol aminopeptidase family, N-terminal domain Zip PF02535.17 CDI84229.1 - 4.4 6.2 10.8 25 3.7 0.0 2.3 2 0 0 2 2 2 0 ZIP Zinc transporter Ufd2P_core PF10408.4 CDI84229.1 - 5.6 5.0 16.8 14 3.7 9.8 2.0 2 0 0 2 2 2 0 Ubiquitin elongating factor core G0-G1_switch_2 PF15103.1 CDI84229.1 - 8.9 6.6 16.3 31 4.8 7.0 2.6 2 0 0 2 2 2 0 G0/G1 switch protein 2 Glyco_transf_15 PF01793.11 CDI84229.1 - 9.2 5.0 11.5 5.4 5.8 5.0 2.0 2 0 0 2 2 2 0 Glycolipid 2-alpha-mannosyltransferase Med15 PF09606.5 CDI84234.1 - 0.0013 17.0 125.6 0.0014 16.9 87.1 1.2 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal PAT1 PF09770.4 CDI84234.1 - 0.0017 16.6 98.6 0.0019 16.5 68.3 1.1 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 HSP70 PF00012.15 CDI84234.1 - 0.18 9.6 29.0 0.17 9.7 20.1 1.2 1 0 0 1 1 1 0 Hsp70 protein Activator_LAG-3 PF11498.3 CDI84235.1 - 0.004 15.9 7.9 0.004 15.9 5.5 1.1 1 0 0 1 1 1 1 Transcriptional activator LAG-3 UreF PF01730.11 CDI84235.1 - 0.044 13.8 7.3 0.052 13.6 5.1 1.1 1 0 0 1 1 1 0 UreF PHD_3 PF13922.1 CDI84235.1 - 0.18 12.0 4.3 0.23 11.7 3.0 1.2 1 0 0 1 1 1 0 PHD domain of transcriptional enhancer, Asx Prenyltrans_1 PF13243.1 CDI84235.1 - 0.2 11.6 3.0 0.28 11.1 2.1 1.3 1 0 0 1 1 1 0 Prenyltransferase-like Pex14_N PF04695.8 CDI84235.1 - 0.24 11.4 3.8 0.3 11.1 2.7 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region CDK2AP PF09806.4 CDI84235.1 - 0.29 11.3 10.0 0.34 11.1 6.9 1.0 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein DUF3380 PF11860.3 CDI84235.1 - 0.67 9.9 4.3 0.76 9.7 3.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3380) SP2 PF03014.9 CDI84235.1 - 1.1 7.1 9.0 1.1 6.9 6.2 1.0 1 0 0 1 1 1 0 Structural protein 2 TRSP PF12500.3 CDI84235.1 - 1.2 8.6 4.0 1.3 8.4 2.8 1.0 1 0 0 1 1 1 0 TRSP domain C terminus to PRTase_2 Robl_LC7 PF03259.12 CDI84235.1 - 2 8.0 4.2 2.6 7.6 2.9 1.2 1 0 0 1 1 1 0 Roadblock/LC7 domain Med15 PF09606.5 CDI84235.1 - 2.9 5.9 14.9 3.2 5.8 10.3 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal TraV PF09676.5 CDI84235.1 - 3.2 8.4 7.4 3.5 8.3 5.1 1.1 1 0 0 1 1 1 0 Type IV conjugative transfer system lipoprotein (TraV) DUF4407 PF14362.1 CDI84235.1 - 4.2 6.2 9.6 5.7 5.7 6.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TALPID3 PF15324.1 CDI84235.1 - 8.9 3.5 10.3 10 3.3 7.2 1.0 1 0 0 1 1 1 0 Hedgehog signalling target SpaB_C PF14028.1 CDI84235.1 - 8.9 5.7 9.8 9.7 5.6 6.8 1.0 1 0 0 1 1 1 0 SpaB C-terminal domain Exo_endo_phos PF03372.18 CDI84241.1 - 3.5e-19 69.7 0.8 1.5e-17 64.4 0.0 2.3 2 0 0 2 2 2 2 Endonuclease/Exonuclease/phosphatase family PrgH PF09480.5 CDI84242.1 - 0.075 11.8 0.0 0.1 11.4 0.0 1.1 1 0 0 1 1 1 0 Type III secretion system protein PrgH-EprH (PrgH) AAA PF00004.24 CDI84243.1 - 8.4e-39 132.7 0.0 2.7e-38 131.1 0.0 1.9 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 CDI84243.1 - 7.9e-06 25.6 0.1 4.2e-05 23.3 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 CDI84243.1 - 2.2e-05 24.5 0.2 0.0012 18.9 0.1 2.8 1 1 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.7 CDI84243.1 - 3.4e-05 23.0 0.0 7.8e-05 21.8 0.0 1.7 1 1 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_2 PF07724.9 CDI84243.1 - 0.00032 20.6 0.0 0.0015 18.5 0.0 2.0 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 CDI84243.1 - 0.00033 20.8 0.3 0.014 15.5 0.2 2.6 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 CDI84243.1 - 0.0026 17.6 0.0 0.0073 16.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 CDI84243.1 - 0.0031 16.6 0.1 0.013 14.7 0.0 2.0 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.12 CDI84243.1 - 0.005 16.2 0.0 0.0098 15.3 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_19 PF13245.1 CDI84243.1 - 0.0051 16.5 0.3 0.014 15.1 0.2 1.7 1 0 0 1 1 1 1 Part of AAA domain PhoH PF02562.11 CDI84243.1 - 0.0074 15.5 0.0 0.015 14.5 0.0 1.5 1 0 0 1 1 1 1 PhoH-like protein KaiC PF06745.8 CDI84243.1 - 0.011 14.9 0.2 0.13 11.3 0.0 2.4 2 0 0 2 2 2 0 KaiC DUF815 PF05673.8 CDI84243.1 - 0.013 14.4 0.0 0.022 13.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_17 PF13207.1 CDI84243.1 - 0.02 15.6 0.5 0.08 13.7 0.1 2.3 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.1 CDI84243.1 - 0.022 14.1 0.8 0.1 11.9 0.2 2.4 2 1 0 2 2 2 0 AAA domain AAA_24 PF13479.1 CDI84243.1 - 0.031 13.8 0.1 0.065 12.8 0.1 1.5 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 CDI84243.1 - 0.036 13.1 0.1 0.075 12.1 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin TIP49 PF06068.8 CDI84243.1 - 0.037 12.7 1.0 0.21 10.2 0.0 2.1 1 1 0 2 2 2 0 TIP49 C-terminus AAA_14 PF13173.1 CDI84243.1 - 0.05 13.5 0.0 0.12 12.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 CDI84243.1 - 0.071 12.5 0.0 0.35 10.3 0.0 2.1 2 0 0 2 2 2 0 Sigma-54 interaction domain DUF904 PF06005.7 CDI84243.1 - 0.18 12.1 3.7 0.23 11.7 0.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF904) TCL1_MTCP1 PF01840.12 CDI84261.1 - 0.0012 18.2 2.8 0.0016 17.9 1.9 1.2 1 0 0 1 1 1 1 TCL1/MTCP1 family Peptidase_S49_N PF08496.5 CDI84261.1 - 0.015 15.0 5.4 0.02 14.6 3.8 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Bac_luciferase PF00296.15 CDI84261.1 - 0.019 14.0 0.5 0.022 13.9 0.3 1.1 1 0 0 1 1 1 0 Luciferase-like monooxygenase ODV-E18 PF10717.4 CDI84261.1 - 0.05 13.0 5.3 0.34 10.3 0.5 2.3 2 0 0 2 2 2 0 Occlusion-derived virus envelope protein ODV-E18 RNase_HII PF01351.13 CDI84261.1 - 0.057 13.0 4.2 0.02 14.5 1.5 1.3 1 1 0 1 1 1 0 Ribonuclease HII SoxE PF06525.6 CDI84261.1 - 0.078 12.2 0.2 0.11 11.7 0.2 1.2 1 0 0 1 1 1 0 Sulfocyanin (SoxE) Nucleoside_tran PF01733.13 CDI84261.1 - 0.11 11.6 0.9 0.12 11.4 0.7 1.0 1 0 0 1 1 1 0 Nucleoside transporter UPF0370 PF13980.1 CDI84261.1 - 0.21 11.3 1.9 0.21 11.4 0.5 1.6 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0370) DUF4367 PF14285.1 CDI84261.1 - 0.28 10.4 3.6 0.49 9.6 2.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4367) DUF4446 PF14584.1 CDI84261.1 - 0.38 10.5 4.3 0.56 10.0 3.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) DUF4389 PF14333.1 CDI84261.1 - 0.74 9.5 3.0 1.1 9.0 2.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4389) Protocadherin PF08374.6 CDI84261.1 - 3.9 7.0 8.1 0.83 9.2 1.0 2.0 2 0 0 2 2 2 0 Protocadherin EphA2_TM PF14575.1 CDI84261.1 - 4.1 7.8 14.4 1.1e+02 3.2 9.9 2.2 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain RskA PF10099.4 CDI84261.1 - 4.6 6.9 16.0 9.2 5.9 11.1 1.6 1 1 0 1 1 1 0 Anti-sigma-K factor rskA SP_C-Propep PF08999.5 CDI84261.1 - 4.9 6.6 11.9 6.9 6.2 8.2 1.4 1 1 0 1 1 1 0 Surfactant protein C, N terminal propeptide Claudin_2 PF13903.1 CDI84261.1 - 6.1 6.5 6.6 1.4 8.5 0.3 2.1 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction Ribosomal_60s PF00428.14 CDI84261.1 - 6.2 7.2 10.1 12 6.3 7.0 1.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein Shisa PF13908.1 CDI84261.1 - 6.6 6.8 11.6 10 6.2 8.0 1.3 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator DUF929 PF06053.6 CDI84261.1 - 8.5 5.3 6.7 13 4.7 4.6 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF929) DUF668 PF05003.7 CDI84283.1 - 0.33 11.1 7.5 1.1 9.5 1.8 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF668) Inositol_P PF00459.20 CDI84283.1 - 0.59 9.3 6.1 0.62 9.3 4.3 1.0 1 0 0 1 1 1 0 Inositol monophosphatase family DUF448 PF04296.8 CDI84283.1 - 1.9 8.1 7.2 5.2 6.7 2.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF448) VitD-bind_III PF09164.5 CDI84283.1 - 1.9 8.1 6.5 72 3.1 4.5 2.1 1 1 0 1 1 1 0 Vitamin D binding protein, domain III DUF1694 PF07997.6 CDI84283.1 - 2.3 8.1 13.7 2.5 8.0 9.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1694) AMP-binding_C_2 PF14535.1 CDI84283.1 - 3.4 7.7 6.2 22 5.1 4.3 2.0 1 1 0 1 1 1 0 AMP-binding enzyme C-terminal domain DUF3646 PF12362.3 CDI84283.1 - 5 7.0 12.7 11 6.0 2.7 2.1 1 1 1 2 2 2 0 DNA polymerase III gamma and tau subunits C terminal HI0933_like PF03486.9 CDI84283.1 - 5.8 5.2 15.8 6.7 5.0 11.0 1.1 1 0 0 1 1 1 0 HI0933-like protein FHIPEP PF00771.15 CDI84283.1 - 6.4 4.9 17.1 6.6 4.9 11.8 1.0 1 0 0 1 1 1 0 FHIPEP family Band_7_1 PF13421.1 CDI84283.1 - 9.2 5.7 8.5 10 5.5 5.9 1.1 1 0 0 1 1 1 0 SPFH domain-Band 7 family Prenyltrans PF00432.16 CDI84294.1 - 1.4e-38 130.1 22.3 7.8e-09 34.9 0.2 6.5 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 CDI84294.1 - 4.7e-34 117.1 0.2 2.4e-13 50.4 0.0 3.8 2 2 2 4 4 4 3 Prenyltransferase-like Prenyltrans_1 PF13243.1 CDI84294.1 - 3.5e-08 33.4 0.0 0.042 13.8 0.0 3.5 1 1 3 4 4 4 4 Prenyltransferase-like A2M_comp PF07678.9 CDI84294.1 - 0.028 13.6 0.0 16 4.5 0.0 3.0 3 0 0 3 3 3 0 A-macroglobulin complement component MFS_1 PF07690.11 CDI84295.1 - 1.5e-16 60.0 28.3 7.7e-12 44.5 9.3 2.6 1 1 1 3 3 3 2 Major Facilitator Superfamily MFS_2 PF13347.1 CDI84295.1 - 7.6e-06 24.5 8.6 1.1e-05 24.0 5.9 1.2 1 0 0 1 1 1 1 MFS/sugar transport protein CDC50 PF03381.10 CDI84297.1 - 9.6e-27 93.8 0.0 1.5e-26 93.2 0.0 1.3 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family Mlo PF03094.10 CDI84298.1 - 0.0005 18.3 11.2 0.025 12.7 6.9 2.8 1 1 1 2 2 2 1 Mlo family EF-hand_6 PF13405.1 CDI84298.1 - 0.00092 18.9 0.5 0.0043 16.8 0.4 2.1 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.1 CDI84298.1 - 0.0082 16.2 0.2 0.045 13.8 0.0 2.4 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 CDI84298.1 - 0.02 14.1 2.5 0.088 12.1 1.7 2.1 1 0 0 1 1 1 0 EF hand EF-hand_8 PF13833.1 CDI84298.1 - 0.047 13.3 1.9 0.11 12.1 1.3 1.6 1 0 0 1 1 1 0 EF-hand domain pair DFP PF04127.10 CDI84299.1 - 1.1e-09 38.1 0.0 2.5e-09 37.0 0.0 1.6 1 0 0 1 1 1 1 DNA / pantothenate metabolism flavoprotein Med15 PF09606.5 CDI84299.1 - 0.015 13.5 29.4 0.019 13.2 2.3 2.1 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal Spt20 PF12090.3 CDI84299.1 - 0.02 14.2 8.3 0.43 9.9 1.0 2.3 2 0 0 2 2 2 0 Spt20 family zf-DHHC PF01529.15 CDI84299.1 - 0.032 13.6 1.0 1 8.7 0.1 2.2 2 0 0 2 2 2 0 DHHC palmitoyltransferase DUF2250 PF10007.4 CDI84299.1 - 0.077 12.9 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2250) Zip PF02535.17 CDI84299.1 - 0.082 11.8 3.7 0.16 10.9 0.8 2.0 2 0 0 2 2 2 0 ZIP Zinc transporter DUF4557 PF15101.1 CDI84299.1 - 0.13 12.1 17.5 0.34 10.7 5.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4557) Daxx PF03344.10 CDI84299.1 - 0.13 10.7 23.1 0.17 10.3 16.0 1.1 1 0 0 1 1 1 0 Daxx Family AAA_23 PF13476.1 CDI84299.1 - 0.13 12.5 10.2 0.14 12.4 1.3 2.2 2 0 0 2 2 2 0 AAA domain DUF3801 PF12687.2 CDI84299.1 - 0.48 9.9 11.7 0.86 9.1 3.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3801) EIIBC-GUT_N PF03612.9 CDI84299.1 - 8.7 5.9 9.8 1.4 8.4 1.1 2.6 3 0 0 3 3 3 0 Sorbitol phosphotransferase enzyme II N-terminus TPR_1 PF00515.23 CDI84301.1 - 7.9e-13 47.4 0.8 6.8e-07 28.6 0.0 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.1 CDI84301.1 - 1.2e-09 37.6 0.4 1.2e-09 37.6 0.3 2.8 3 1 1 4 4 3 1 TPR repeat TPR_2 PF07719.12 CDI84301.1 - 4.9e-07 29.1 0.4 1.2e-05 24.7 0.0 3.6 4 0 0 4 4 2 2 Tetratricopeptide repeat TPR_9 PF13371.1 CDI84301.1 - 9.8e-06 25.3 0.8 9.8e-06 25.3 0.6 3.0 1 1 2 3 3 2 1 Tetratricopeptide repeat FLO_LFY PF01698.11 CDI84301.1 - 0.00059 18.7 19.3 0.00095 18.1 13.4 1.2 1 0 0 1 1 1 1 Floricaula / Leafy protein PAT1 PF09770.4 CDI84301.1 - 0.0043 15.3 48.2 0.0051 15.1 33.4 1.2 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 CDC45 PF02724.9 CDI84301.1 - 0.037 12.0 23.6 0.048 11.7 16.3 1.1 1 0 0 1 1 1 0 CDC45-like protein TPR_8 PF13181.1 CDI84301.1 - 0.041 13.6 0.3 0.21 11.4 0.0 2.4 2 0 0 2 2 1 0 Tetratricopeptide repeat DUF4045 PF13254.1 CDI84301.1 - 0.043 13.1 18.4 0.059 12.6 12.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) eIF-3_zeta PF05091.7 CDI84301.1 - 0.046 12.3 23.1 0.057 12.0 16.0 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) SAPS PF04499.10 CDI84301.1 - 0.067 11.8 17.6 0.08 11.5 12.2 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein SOBP PF15279.1 CDI84301.1 - 0.078 13.3 17.8 0.1 12.9 12.4 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein Peptidase_S64 PF08192.6 CDI84301.1 - 0.087 11.1 12.8 0.093 11.0 8.8 1.3 1 0 0 1 1 1 0 Peptidase family S64 Ycf1 PF05758.7 CDI84301.1 - 0.1 10.2 21.7 0.12 10.1 15.0 1.1 1 0 0 1 1 1 0 Ycf1 DUF4638 PF15472.1 CDI84301.1 - 0.14 11.7 18.5 0.19 11.2 12.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) DUF1510 PF07423.6 CDI84301.1 - 0.17 11.2 29.7 0.29 10.4 20.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) SPX PF03105.14 CDI84301.1 - 0.28 10.9 26.1 0.4 10.4 18.1 1.2 1 0 0 1 1 1 0 SPX domain Raftlin PF15250.1 CDI84301.1 - 0.31 9.5 21.2 0.41 9.1 14.7 1.2 1 0 0 1 1 1 0 Raftlin DHHW PF14286.1 CDI84301.1 - 0.55 9.4 22.6 0.82 8.9 15.7 1.2 1 0 0 1 1 1 0 DHHW protein Neur_chan_memb PF02932.11 CDI84301.1 - 0.57 10.0 18.1 0.82 9.5 12.5 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Cwf_Cwc_15 PF04889.7 CDI84301.1 - 0.57 9.8 30.6 0.85 9.2 21.2 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Presenilin PF01080.12 CDI84301.1 - 0.59 8.8 13.7 0.78 8.4 9.5 1.2 1 0 0 1 1 1 0 Presenilin Cellulose_synt PF03552.9 CDI84301.1 - 0.66 8.2 9.6 0.82 7.8 6.6 1.2 1 0 0 1 1 1 0 Cellulose synthase TT_ORF1 PF02956.9 CDI84301.1 - 0.66 8.3 15.9 0.85 8.0 11.0 1.1 1 0 0 1 1 1 0 TT viral orf 1 TPR_17 PF13431.1 CDI84301.1 - 0.97 9.8 0.0 0.97 9.8 0.0 3.8 4 1 0 4 4 2 0 Tetratricopeptide repeat BTV_NS2 PF04514.7 CDI84301.1 - 1 8.1 20.3 1.4 7.7 14.1 1.2 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 FAM91_C PF14648.1 CDI84301.1 - 1.1 8.0 10.0 1.4 7.7 6.9 1.3 1 0 0 1 1 1 0 FAM91 C-terminus DUF4220 PF13968.1 CDI84301.1 - 1.2 8.1 9.3 1.4 7.8 6.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4220) PLRV_ORF5 PF01690.12 CDI84301.1 - 1.5 7.8 24.7 1.9 7.5 17.1 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein DNA_pol_viral_N PF00242.12 CDI84301.1 - 1.7 7.6 20.7 2.1 7.2 14.3 1.2 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain CobT PF06213.7 CDI84301.1 - 2 7.4 25.1 3.9 6.5 17.4 1.4 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Hid1 PF12722.2 CDI84301.1 - 2.6 5.6 29.7 3.2 5.3 20.6 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Zip PF02535.17 CDI84301.1 - 4.6 6.1 11.2 6.8 5.5 7.8 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Dicty_REP PF05086.7 CDI84301.1 - 4.9 4.7 18.5 5.9 4.5 12.8 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF966 PF06136.8 CDI84301.1 - 5.2 6.3 25.4 7.1 5.9 17.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF966) RNA_pol_Rpb1_5 PF04998.12 CDI84301.1 - 6.6 5.8 16.0 9.1 5.4 11.1 1.2 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 DUF4106 PF13388.1 CDI84301.1 - 9.7 5.0 32.1 16 4.3 22.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) DUF4392 PF14336.1 CDI84305.1 - 0.093 11.5 0.2 0.19 10.4 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4392) SR-25 PF10500.4 CDI84313.1 - 0.067 12.6 19.2 0.091 12.2 13.3 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein CDK2AP PF09806.4 CDI84313.1 - 0.12 12.6 23.6 0.13 12.5 16.3 1.0 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein DUF3827 PF12877.2 CDI84313.1 - 1.2 7.1 17.8 1.3 7.0 12.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) FAM60A PF15396.1 CDI84313.1 - 1.3 8.7 18.3 1.4 8.6 12.7 1.0 1 0 0 1 1 1 0 Protein Family FAM60A Pox_Ag35 PF03286.9 CDI84313.1 - 1.7 8.1 17.3 1.9 7.9 12.0 1.0 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DUF4647 PF15504.1 CDI84313.1 - 1.9 7.2 23.1 2 7.1 16.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4647) NST1 PF13945.1 CDI84313.1 - 2.1 8.3 26.9 2.4 8.1 18.6 1.0 1 0 0 1 1 1 0 Salt tolerance down-regulator Vfa1 PF08432.5 CDI84313.1 - 2.9 7.8 22.0 3.1 7.7 15.3 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Plasmodium_Vir PF05795.6 CDI84313.1 - 3.1 6.9 10.9 3.4 6.7 7.5 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Band_3_cyto PF07565.8 CDI84313.1 - 7.8 5.9 15.5 10 5.5 10.7 1.3 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Mitofilin PF09731.4 CDI84313.1 - 7.8 5.0 24.7 8.4 4.9 17.1 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Nop53 PF07767.6 CDI84313.1 - 8.1 5.3 27.6 9.5 5.0 19.2 1.0 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) DUF2052 PF09747.4 CDI84313.1 - 9.7 6.0 22.9 11 5.8 15.8 1.1 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) DUF3357 PF11837.3 CDI84325.1 - 0.0017 18.1 4.0 0.0017 18.1 2.8 3.5 1 1 1 2 2 1 1 Domain of unknown function (DUF3357) Med15 PF09606.5 CDI84325.1 - 0.0068 14.6 62.1 0.0086 14.3 43.1 1.0 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal Med1 PF10744.4 CDI84325.1 - 0.047 12.4 11.7 0.056 12.2 8.1 1.0 1 0 0 1 1 1 0 Mediator of RNA polymerase II transcription subunit 1 SOBP PF15279.1 CDI84325.1 - 0.14 12.4 25.8 0.17 12.2 17.9 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein Utp14 PF04615.8 CDI84325.1 - 0.2 9.8 26.7 0.24 9.5 18.5 1.1 1 0 0 1 1 1 0 Utp14 protein Cwf_Cwc_15 PF04889.7 CDI84325.1 - 0.3 10.7 24.6 0.1 12.2 7.9 2.0 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Ycf1 PF05758.7 CDI84325.1 - 0.31 8.7 16.6 0.39 8.3 11.5 1.2 1 0 0 1 1 1 0 Ycf1 YjgP_YjgQ PF03739.9 CDI84325.1 - 0.58 8.8 5.5 0.69 8.5 3.8 1.2 1 0 0 1 1 1 0 Predicted permease YjgP/YjgQ family PAT1 PF09770.4 CDI84325.1 - 1.3 7.1 50.4 1.6 6.8 34.9 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF3391 PF11871.3 CDI84325.1 - 1.7 8.8 19.1 0.82 9.8 1.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3391) DUF737 PF05300.6 CDI84325.1 - 2.6 7.9 30.2 1 9.2 11.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF737) RR_TM4-6 PF06459.7 CDI84325.1 - 2.8 7.7 28.3 0.29 11.0 9.5 2.1 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Bud13 PF09736.4 CDI84325.1 - 3.2 8.0 30.9 3.2 8.0 10.8 2.2 2 0 0 2 2 2 0 Pre-mRNA-splicing factor of RES complex DUF1180 PF06679.7 CDI84325.1 - 3.7 7.4 14.3 0.91 9.3 7.5 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1180) DUF4661 PF15576.1 CDI84325.1 - 4.2 6.9 12.3 6.1 6.4 8.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4661) Hid1 PF12722.2 CDI84325.1 - 4.5 4.8 26.9 6.2 4.3 18.6 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein TMEM237 PF15383.1 CDI84325.1 - 5.2 6.1 14.5 8.9 5.3 10.0 1.3 1 0 0 1 1 1 0 Transmembrane protein 237 DUF3899 PF13038.1 CDI84325.1 - 5.5 7.2 7.7 3.9 7.6 0.8 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF3899) U1snRNP70_N PF12220.3 CDI84325.1 - 5.6 7.3 25.5 3.6 7.9 3.8 2.3 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal CRT10 PF08728.5 CDI84325.1 - 6.7 4.5 18.4 7.9 4.3 12.8 1.0 1 0 0 1 1 1 0 CRT10 PRP1_N PF06424.7 CDI84325.1 - 8 6.7 20.2 6.1 7.1 6.3 2.2 2 0 0 2 2 2 0 PRP1 splicing factor, N-terminal Spore_coat_CotO PF14153.1 CDI84325.1 - 8.8 5.7 36.8 1.9 7.8 13.2 2.1 2 0 0 2 2 2 0 Spore coat protein CotO FimP PF09766.4 CDI84328.1 - 0.00061 18.9 8.9 0.00061 18.9 6.1 1.1 1 0 0 1 1 1 1 Fms-interacting protein Med15 PF09606.5 CDI84328.1 - 0.00081 17.7 24.6 0.00081 17.7 17.1 1.0 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal Oleosin PF01277.12 CDI84328.1 - 0.0017 17.8 0.1 0.002 17.7 0.1 1.1 1 0 0 1 1 1 1 Oleosin RskA PF10099.4 CDI84328.1 - 0.011 15.4 7.1 0.012 15.3 4.9 1.2 1 0 0 1 1 1 0 Anti-sigma-K factor rskA Ribosomal_60s PF00428.14 CDI84328.1 - 0.021 15.2 1.4 0.031 14.6 1.0 1.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein Spt20 PF12090.3 CDI84328.1 - 0.023 14.0 5.9 0.023 14.0 4.1 1.3 1 0 0 1 1 1 0 Spt20 family Suf PF05843.9 CDI84328.1 - 0.025 14.3 9.0 0.023 14.4 6.3 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Prog_receptor PF02161.10 CDI84328.1 - 0.047 12.5 7.9 0.052 12.3 5.5 1.1 1 0 0 1 1 1 0 Progesterone receptor Serinc PF03348.10 CDI84328.1 - 0.048 12.3 5.0 0.047 12.4 3.5 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) Ctr PF04145.10 CDI84328.1 - 0.093 12.7 1.1 0.11 12.4 0.8 1.2 1 0 0 1 1 1 0 Ctr copper transporter family Glt_symporter PF03616.9 CDI84328.1 - 0.11 10.9 0.8 0.13 10.7 0.6 1.1 1 0 0 1 1 1 0 Sodium/glutamate symporter DDHD PF02862.12 CDI84328.1 - 0.19 11.5 3.8 0.17 11.6 2.7 1.1 1 0 0 1 1 1 0 DDHD domain DUF4557 PF15101.1 CDI84328.1 - 0.32 10.7 12.5 0.32 10.7 8.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) Gag_spuma PF03276.9 CDI84328.1 - 0.51 8.6 15.2 0.53 8.5 10.5 1.0 1 0 0 1 1 1 0 Spumavirus gag protein HA2 PF04408.18 CDI84328.1 - 0.53 10.3 3.4 0.77 9.8 2.3 1.3 1 1 0 1 1 1 0 Helicase associated domain (HA2) MDFI PF15316.1 CDI84328.1 - 0.62 10.0 3.3 0.71 9.8 2.3 1.1 1 0 0 1 1 1 0 MyoD family inhibitor TFIIA PF03153.8 CDI84328.1 - 0.63 9.8 17.3 0.59 9.9 12.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit R_equi_Vir PF05526.6 CDI84328.1 - 0.96 9.0 5.9 1.1 8.8 4.1 1.1 1 0 0 1 1 1 0 Rhodococcus equi virulence-associated protein FNIP_N PF14636.1 CDI84328.1 - 1.3 9.4 10.3 1.6 9.1 7.1 1.1 1 0 0 1 1 1 0 Folliculin-interacting protein N-terminus Med13_N PF11597.3 CDI84328.1 - 1.7 7.2 11.0 1.6 7.3 7.6 1.1 1 0 0 1 1 1 0 Mediator complex subunit 13 N-terminal ERF PF04404.7 CDI84328.1 - 1.7 8.1 15.4 1.9 7.9 10.6 1.2 1 0 0 1 1 1 0 ERF superfamily AIF_C PF14721.1 CDI84328.1 - 3.6 7.8 7.3 5 7.3 5.1 1.3 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term DUF1071 PF06378.6 CDI84328.1 - 8.1 5.5 9.0 9.3 5.3 6.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1071) DUF844 PF05815.6 CDI84328.1 - 8.2 5.1 10.6 9.5 4.9 7.3 1.0 1 0 0 1 1 1 0 Baculovirus protein of unknown function (DUF844) Pex14_N PF04695.8 CDI84328.1 - 8.8 6.3 19.7 12 5.9 13.7 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region SR-25 PF10500.4 CDI84331.1 - 0.03 13.8 14.5 0.036 13.5 10.1 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein WBP-1 PF11669.3 CDI84331.1 - 0.31 11.1 2.2 0.57 10.2 1.5 1.4 1 0 0 1 1 1 0 WW domain-binding protein 1 APC_CDC26 PF10471.4 CDI84331.1 - 5.3 7.8 16.0 0.23 12.2 6.0 2.4 2 1 1 3 3 3 0 Anaphase-promoting complex APC subunit 1 NaeI PF09126.5 CDI84338.1 - 0.0073 14.9 0.1 1.6 7.3 0.0 2.2 2 0 0 2 2 2 2 Restriction endonuclease NaeI DUF1746 PF08508.5 CDI84338.1 - 0.023 14.6 1.3 5.7 6.9 0.0 3.0 2 1 1 3 3 3 0 Fungal domain of unknown function (DUF1746) Antifungal_pept PF11410.3 CDI84338.1 - 0.061 13.4 15.8 0.53 10.4 0.6 3.2 3 0 0 3 3 3 0 Antifungal peptide Phage_P2_GpU PF06995.6 CDI84338.1 - 0.14 11.5 0.1 3.4 7.0 0.0 2.1 2 0 0 2 2 2 0 Phage P2 GpU DUF2953 PF11167.3 CDI84338.1 - 0.59 10.0 4.6 33 4.4 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2953) Thioredoxin PF00085.15 CDI84346.1 - 6.9e-29 99.5 0.3 7.6e-29 99.4 0.2 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 CDI84346.1 - 5.2e-06 26.6 0.3 6.8e-05 23.0 0.2 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 CDI84346.1 - 8.1e-05 22.6 0.0 0.00014 21.9 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_9 PF14595.1 CDI84346.1 - 0.00011 21.7 0.1 0.00011 21.7 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Glutaredoxin PF00462.19 CDI84346.1 - 0.00073 19.4 0.0 0.0011 18.8 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin KaiB PF07689.7 CDI84346.1 - 0.0031 16.9 0.0 0.0053 16.1 0.0 1.5 2 0 0 2 2 2 1 KaiB domain Redoxin PF08534.5 CDI84346.1 - 0.019 14.5 0.7 0.17 11.4 0.1 2.0 1 1 1 2 2 2 0 Redoxin Thioredoxin_7 PF13899.1 CDI84346.1 - 0.034 14.1 0.0 0.054 13.5 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin-like DUF3801 PF12687.2 CDI84356.1 - 0.12 11.9 12.1 0.13 11.7 8.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3801) CAF-1_p150 PF11600.3 CDI84356.1 - 0.23 10.8 25.8 0.26 10.6 17.9 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal SAGA-Tad1 PF12767.2 CDI84356.1 - 0.56 9.8 22.3 0.59 9.7 15.5 1.1 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit DUF3827 PF12877.2 CDI84356.1 - 2.1 6.3 20.2 2.4 6.1 14.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) Suf PF05843.9 CDI84356.1 - 2.2 7.9 20.3 2.4 7.8 14.1 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) SprA-related PF12118.3 CDI84356.1 - 2.7 7.2 37.8 3.2 6.9 26.2 1.1 1 0 0 1 1 1 0 SprA-related family Parvo_coat PF00740.13 CDI84356.1 - 5 5.9 19.0 5.1 5.9 13.2 1.0 1 0 0 1 1 1 0 Parvovirus coat protein VP2 Macoilin PF09726.4 CDI84356.1 - 5.4 5.1 27.8 7.8 4.6 19.3 1.2 1 0 0 1 1 1 0 Transmembrane protein Med15 PF09606.5 CDI84356.1 - 6.2 4.8 38.9 7.1 4.6 27.0 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal ECM1 PF05782.6 CDI84356.1 - 7.5 5.1 16.5 8.4 4.9 11.4 1.0 1 0 0 1 1 1 0 Extracellular matrix protein 1 (ECM1) SR-25 PF10500.4 CDI84356.1 - 8.4 5.7 44.4 25 4.2 30.8 1.7 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein RR_TM4-6 PF06459.7 CDI84356.1 - 8.8 6.1 13.9 8.7 6.1 9.6 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 AUX_IAA PF02309.11 CDI84356.1 - 9.3 5.9 15.2 11 5.6 10.5 1.3 1 0 0 1 1 1 0 AUX/IAA family Ycf1 PF05758.7 CDI84357.1 - 0.08 10.6 11.8 0.12 10.0 8.2 1.2 1 0 0 1 1 1 0 Ycf1 SprA-related PF12118.3 CDI84357.1 - 0.092 12.0 48.0 0.27 10.5 6.7 2.1 2 0 0 2 2 2 0 SprA-related family CDC45 PF02724.9 CDI84357.1 - 0.13 10.3 13.0 0.18 9.8 9.0 1.2 1 0 0 1 1 1 0 CDC45-like protein Ureide_permease PF07168.6 CDI84357.1 - 0.17 10.5 0.5 0.21 10.1 0.3 1.2 1 0 0 1 1 1 0 Ureide permease DUF2052 PF09747.4 CDI84357.1 - 0.18 11.7 21.2 0.18 11.7 6.1 2.1 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) DUF1510 PF07423.6 CDI84357.1 - 0.22 10.8 19.3 0.092 12.0 7.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) FAM176 PF14851.1 CDI84357.1 - 1.5 8.4 9.9 0.24 11.0 2.5 2.2 2 0 0 2 2 2 0 FAM176 family DUF572 PF04502.8 CDI84357.1 - 1.9 7.6 18.9 3.4 6.7 13.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF572) EphA2_TM PF14575.1 CDI84357.1 - 1.9 8.9 10.4 10 6.6 0.2 3.3 3 0 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain PAT1 PF09770.4 CDI84357.1 - 2.3 6.3 43.7 3.2 5.8 30.3 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF3595 PF12166.3 CDI84357.1 - 3.5 6.3 13.5 4.2 6.0 9.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3595) Bud13 PF09736.4 CDI84357.1 - 5.5 7.2 23.9 4.7 7.4 9.0 2.3 2 0 0 2 2 2 0 Pre-mRNA-splicing factor of RES complex UPF0564 PF10595.4 CDI84357.1 - 7.3 5.3 28.7 0.52 9.1 9.6 2.1 2 0 0 2 2 2 0 Uncharacterised protein family UPF0564 DUF1510 PF07423.6 CDI84360.1 - 0.24 10.7 20.9 0.26 10.6 14.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Mitofilin PF09731.4 CDI84360.1 - 0.31 9.6 24.9 0.34 9.5 17.3 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein DUF1003 PF06210.6 CDI84360.1 - 0.4 10.6 3.7 0.59 10.0 2.6 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1003) POX PF07526.6 CDI84360.1 - 0.46 10.7 17.0 0.48 10.6 11.8 1.0 1 0 0 1 1 1 0 Associated with HOX Potyvirid-P3 PF13608.1 CDI84360.1 - 0.6 9.1 16.2 0.65 9.0 11.3 1.1 1 0 0 1 1 1 0 Protein P3 of Potyviral polyprotein Serinc PF03348.10 CDI84360.1 - 1.1 7.9 6.9 1.3 7.6 4.8 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) RP-C_C PF11800.3 CDI84360.1 - 1.3 8.6 10.7 1.3 8.7 7.4 1.0 1 0 0 1 1 1 0 Replication protein C C-terminal region DDHD PF02862.12 CDI84360.1 - 1.5 8.5 13.3 1.7 8.3 9.2 1.1 1 0 0 1 1 1 0 DDHD domain Stig1 PF04885.8 CDI84360.1 - 1.5 9.0 8.9 1.7 8.8 6.2 1.1 1 0 0 1 1 1 0 Stigma-specific protein, Stig1 NPR3 PF03666.8 CDI84360.1 - 1.6 7.2 17.2 1.7 7.1 11.9 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 RR_TM4-6 PF06459.7 CDI84360.1 - 1.6 8.5 22.5 1.7 8.4 15.6 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SpoVR PF04293.8 CDI84360.1 - 1.8 6.8 13.1 1.8 6.8 9.1 1.0 1 0 0 1 1 1 0 SpoVR like protein FAM176 PF14851.1 CDI84360.1 - 1.8 8.2 8.4 2.3 7.8 5.9 1.2 1 0 0 1 1 1 0 FAM176 family Tox-ODYAM1 PF15642.1 CDI84360.1 - 1.9 7.0 14.2 2.3 6.8 9.8 1.0 1 0 0 1 1 1 0 Toxin in Odyssella and Amoebophilus DUF106 PF01956.11 CDI84360.1 - 2 7.9 19.0 2.5 7.6 13.1 1.2 1 0 0 1 1 1 0 Integral membrane protein DUF106 AAA_23 PF13476.1 CDI84360.1 - 2.6 8.2 28.4 3.1 8.0 19.7 1.0 1 0 0 1 1 1 0 AAA domain FHIPEP PF00771.15 CDI84360.1 - 2.7 6.1 7.0 3.4 5.8 4.9 1.1 1 0 0 1 1 1 0 FHIPEP family AIF_C PF14721.1 CDI84360.1 - 2.8 8.1 11.7 3.1 8.0 8.1 1.1 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Vfa1 PF08432.5 CDI84360.1 - 3 7.8 32.5 3.5 7.6 22.5 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Folate_carrier PF01770.13 CDI84360.1 - 3.3 6.1 8.8 3.4 6.0 6.1 1.0 1 0 0 1 1 1 0 Reduced folate carrier U79_P34 PF03064.11 CDI84360.1 - 3.5 7.0 21.0 4.3 6.7 14.5 1.1 1 0 0 1 1 1 0 HSV U79 / HCMV P34 DUF3987 PF13148.1 CDI84360.1 - 4 5.8 22.4 4.2 5.8 15.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) YqfQ PF14181.1 CDI84360.1 - 4.1 7.4 26.0 5.6 6.9 18.0 1.2 1 0 0 1 1 1 0 YqfQ-like protein Zip PF02535.17 CDI84360.1 - 4.4 6.2 6.1 4.4 6.2 4.2 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter RNA_pol_Rpb1_2 PF00623.15 CDI84360.1 - 4.8 7.1 13.3 5.2 7.0 9.2 1.1 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 2 Nucleoside_tran PF01733.13 CDI84360.1 - 5.1 6.1 6.3 5.4 6.0 4.4 1.0 1 0 0 1 1 1 0 Nucleoside transporter Tfb4 PF03850.9 CDI84360.1 - 5.3 6.2 8.8 5.5 6.1 6.1 1.1 1 0 0 1 1 1 0 Transcription factor Tfb4 DUF2413 PF10310.4 CDI84360.1 - 5.5 5.6 20.9 6 5.5 14.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) Neur_chan_memb PF02932.11 CDI84360.1 - 6.2 6.6 9.0 7.1 6.4 6.2 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Ycf1 PF05758.7 CDI84360.1 - 6.7 4.2 21.9 6.9 4.2 15.2 1.0 1 0 0 1 1 1 0 Ycf1 Bap31 PF05529.7 CDI84360.1 - 6.9 6.0 26.0 7.7 5.9 18.0 1.0 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like Peroxin-13_N PF04088.8 CDI84360.1 - 7.2 6.5 13.5 9.9 6.0 9.4 1.3 1 0 0 1 1 1 0 Peroxin 13, N-terminal region DUF4446 PF14584.1 CDI84360.1 - 8.2 6.2 12.1 9.7 6.0 8.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) Peptidase_C37 PF05416.7 CDI84360.1 - 8.3 4.5 13.4 8.6 4.5 9.3 1.0 1 0 0 1 1 1 0 Southampton virus-type processing peptidase SID-1_RNA_chan PF13965.1 CDI84360.1 - 9.3 4.2 9.5 9.8 4.2 6.6 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 zf-rbx1 PF12678.2 CDI84364.1 - 2.9e-15 56.1 4.0 7.3e-15 54.8 2.8 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 CDI84364.1 - 0.00023 20.9 2.2 0.00023 20.9 1.5 1.9 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger DUF572 PF04502.8 CDI84364.1 - 0.11 11.6 41.8 0.19 10.9 28.9 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) MIP-T3 PF10243.4 CDI84364.1 - 2.5 6.4 33.8 3.6 5.9 23.4 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Med15 PF09606.5 CDI84364.1 - 2.6 6.1 47.8 3.8 5.5 33.1 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Glt_symporter PF03616.9 CDI84364.1 - 3.5 6.0 4.5 4.6 5.6 3.1 1.1 1 0 0 1 1 1 0 Sodium/glutamate symporter Utp14 PF04615.8 CDI84364.1 - 4.1 5.4 33.4 5.4 5.0 23.2 1.1 1 0 0 1 1 1 0 Utp14 protein DUF936 PF06075.7 CDI84364.1 - 7.5 5.3 41.7 9.3 5.0 28.9 1.0 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) Daxx PF03344.10 CDI84364.1 - 9.7 4.5 38.6 12 4.1 26.8 1.0 1 0 0 1 1 1 0 Daxx Family Kei1 PF08552.6 CDI84378.1 - 0.24 11.0 1.1 0.41 10.2 0.8 1.3 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 Ycf1 PF05758.7 CDI84389.1 - 4.7 4.7 20.5 6.7 4.2 14.2 1.2 1 0 0 1 1 1 0 Ycf1 Macoilin PF09726.4 CDI84389.1 - 9.3 4.3 21.1 11 4.0 14.6 1.1 1 0 0 1 1 1 0 Transmembrane protein DUF2072 PF09845.4 CDI84391.1 - 0.0019 18.1 5.4 0.0019 18.1 3.7 2.4 2 0 0 2 2 2 1 Zn-ribbon containing protein (DUF2072) BLVR PF06375.6 CDI84391.1 - 0.0062 16.3 9.4 0.015 15.1 2.3 2.4 2 0 0 2 2 2 1 Bovine leukaemia virus receptor (BLVR) Pex14_N PF04695.8 CDI84391.1 - 0.012 15.6 8.4 0.012 15.6 5.8 4.7 5 1 0 5 5 4 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Zip PF02535.17 CDI84391.1 - 0.022 13.7 1.2 0.045 12.7 0.1 2.0 2 0 0 2 2 2 0 ZIP Zinc transporter SGT1 PF07093.6 CDI84391.1 - 0.032 12.6 13.9 0.34 9.2 0.6 2.2 2 0 0 2 2 2 0 SGT1 protein DUF4647 PF15504.1 CDI84391.1 - 0.039 12.8 22.8 0.019 13.8 3.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4647) FimP PF09766.4 CDI84391.1 - 0.047 12.7 29.8 0.52 9.3 3.1 2.4 2 0 0 2 2 2 0 Fms-interacting protein Peptidase_U57 PF05582.7 CDI84391.1 - 0.2 10.5 12.4 0.079 11.9 4.2 2.2 2 0 0 2 2 2 0 YabG peptidase U57 DUF1510 PF07423.6 CDI84391.1 - 0.22 10.8 21.4 0.11 11.8 8.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) Apt1 PF10351.4 CDI84391.1 - 0.24 10.2 12.0 0.061 12.1 1.7 2.2 2 0 0 2 2 2 0 Golgi-body localisation protein domain Tfb4 PF03850.9 CDI84391.1 - 0.3 10.2 13.7 0.17 11.1 3.9 2.3 2 0 0 2 2 2 0 Transcription factor Tfb4 Mem_trans PF03547.13 CDI84391.1 - 0.44 8.7 6.5 0.33 9.1 1.3 2.1 2 0 0 2 2 2 0 Membrane transport protein FLO_LFY PF01698.11 CDI84391.1 - 0.7 8.6 17.6 0.21 10.3 5.7 2.3 2 0 0 2 2 2 0 Floricaula / Leafy protein FAM60A PF15396.1 CDI84391.1 - 0.94 9.1 14.6 0.32 10.6 2.7 2.5 2 0 0 2 2 2 0 Protein Family FAM60A DUF2052 PF09747.4 CDI84391.1 - 0.96 9.3 30.4 0.13 12.2 8.8 2.5 2 1 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) Hid1 PF12722.2 CDI84391.1 - 1.5 6.3 22.0 0.049 11.3 4.9 2.1 2 0 0 2 2 2 0 High-temperature-induced dauer-formation protein Nha1_C PF08619.5 CDI84391.1 - 1.7 7.8 26.2 0.027 13.7 4.5 2.3 2 0 0 2 2 2 0 Alkali metal cation/H+ antiporter Nha1 C terminus eIF-3_zeta PF05091.7 CDI84391.1 - 2.3 6.7 24.3 0.046 12.3 7.4 2.1 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Herpes_DNAp_acc PF04929.7 CDI84391.1 - 2.7 6.8 15.1 0.16 10.9 2.5 2.3 2 0 0 2 2 2 0 Herpes DNA replication accessory factor Lipoprotein_X PF03305.8 CDI84391.1 - 4.8 6.4 15.6 1.3 8.3 5.2 2.4 2 0 0 2 2 2 0 Mycoplasma MG185/MG260 protein SpoIIP PF07454.6 CDI84391.1 - 5.1 6.1 17.6 0.7 9.0 6.8 2.2 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) Anoctamin PF04547.7 CDI84391.1 - 5.2 5.6 8.4 0.3 9.6 0.7 2.0 2 0 0 2 2 2 0 Calcium-activated chloride channel Dala_Dala_lig_N PF01820.16 CDI84391.1 - 5.8 7.2 9.8 10 6.4 2.7 2.7 2 0 0 2 2 2 0 D-ala D-ala ligase N-terminus FAM176 PF14851.1 CDI84391.1 - 7.5 6.2 15.7 1.4 8.6 5.6 2.4 2 0 0 2 2 2 0 FAM176 family PH_4 PF15404.1 CDI84391.1 - 7.9 5.9 15.9 4 6.9 5.1 2.5 2 0 0 2 2 2 0 Pleckstrin homology domain Gti1_Pac2 PF09729.4 CDI84391.1 - 9.1 6.1 17.2 1 9.1 4.3 2.5 2 0 0 2 2 2 0 Gti1/Pac2 family Serinc PF03348.10 CDI84391.1 - 9.7 4.7 18.3 1.1 7.9 6.1 2.2 2 0 0 2 2 2 0 Serine incorporator (Serinc) Ribosomal_60s PF00428.14 CDI84393.1 - 0.0053 17.1 1.5 0.0053 17.1 1.1 7.9 5 2 0 5 5 5 3 60s Acidic ribosomal protein Ribosomal_L11_N PF03946.9 CDI84395.1 - 1.3e-16 59.8 0.0 1.9e-16 59.2 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.14 CDI84395.1 - 4.2e-13 49.2 0.1 6.8e-13 48.5 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain TM231 PF10149.4 CDI84395.1 - 0.019 13.9 0.0 0.023 13.6 0.0 1.1 1 0 0 1 1 1 0 Transmembrane protein 231 Ribosomal_L30 PF00327.15 CDI84396.1 - 6.5e-16 57.6 0.3 1.3e-15 56.7 0.2 1.5 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e Ribosomal_L30_N PF08079.7 CDI84396.1 - 3.6e-12 46.1 18.4 8.1e-12 44.9 12.7 1.5 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain Ribosomal_S8e PF01201.17 CDI84396.1 - 0.049 13.7 1.2 0.063 13.4 0.8 1.2 1 0 0 1 1 1 0 Ribosomal protein S8e DUF4051 PF13260.1 CDI84396.1 - 2.7 7.4 5.7 0.53 9.6 0.9 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4051) Steroid_dh PF02544.11 CDI84397.1 - 6.1e-10 39.0 1.2 2.2e-06 27.5 0.0 3.3 4 0 0 4 4 4 2 3-oxo-5-alpha-steroid 4-dehydrogenase ATG22 PF11700.3 CDI84397.1 - 0.0013 17.3 2.9 0.0094 14.4 2.0 2.0 1 1 0 1 1 1 1 Vacuole effluxer Atg22 like Med15 PF09606.5 CDI84397.1 - 0.0054 14.9 22.8 0.013 13.7 0.2 2.0 2 0 0 2 2 2 2 ARC105 or Med15 subunit of Mediator complex non-fungal MARVEL PF01284.18 CDI84397.1 - 0.012 15.4 7.0 15 5.4 0.0 3.3 2 1 1 3 3 3 0 Membrane-associating domain Herpes_env PF01673.13 CDI84397.1 - 0.022 13.3 2.1 0.032 12.7 1.4 1.1 1 0 0 1 1 1 0 Herpesvirus putative major envelope glycoprotein RAB3GAP2_N PF14655.1 CDI84397.1 - 0.026 13.5 8.9 0.99 8.3 0.1 2.1 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Serinc PF03348.10 CDI84397.1 - 0.13 10.9 4.9 0.24 10.0 2.9 1.8 1 1 0 1 1 1 0 Serine incorporator (Serinc) DUF788 PF05620.6 CDI84397.1 - 0.44 10.4 6.5 0.88 9.4 0.6 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF788) Suf PF05843.9 CDI84397.1 - 0.66 9.6 10.2 1.5 8.5 2.1 2.1 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) DUF2489 PF10675.4 CDI84397.1 - 0.7 9.5 13.7 1.9 8.1 0.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2489) SprA-related PF12118.3 CDI84397.1 - 1.2 8.3 19.4 0.062 12.6 9.6 1.6 2 0 0 2 2 2 0 SprA-related family DUF2681 PF10883.3 CDI84397.1 - 4.4 7.5 17.3 7.2 6.8 4.3 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) Ctr PF04145.10 CDI84397.1 - 5.2 7.1 7.6 3.1 7.8 3.4 2.0 3 1 0 3 3 2 0 Ctr copper transporter family zf-RING_2 PF13639.1 CDI84399.1 - 1.3e-07 31.3 8.6 3.7e-06 26.6 3.4 2.9 2 0 0 2 2 2 1 Ring finger domain WWE PF02825.15 CDI84399.1 - 1.1e-06 28.0 1.9 0.0024 17.2 0.1 2.7 2 0 0 2 2 2 2 WWE domain zf-rbx1 PF12678.2 CDI84399.1 - 1.1e-05 25.4 6.9 0.0055 16.7 2.7 2.6 2 0 0 2 2 2 2 RING-H2 zinc finger zf-C3HC4 PF00097.20 CDI84399.1 - 0.0043 16.6 8.4 0.0066 16.0 2.6 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) PHD PF00628.24 CDI84399.1 - 0.0093 15.6 2.3 0.0093 15.6 1.6 2.6 3 0 0 3 3 3 1 PHD-finger zf-Apc11 PF12861.2 CDI84399.1 - 0.044 13.6 1.6 0.32 10.8 0.8 2.4 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.1 CDI84399.1 - 0.32 11.0 8.6 0.41 10.7 3.4 2.5 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CDI84399.1 - 1.1 9.0 8.9 0.36 10.6 2.2 2.8 3 0 0 3 3 3 0 zinc-RING finger domain zf-RING-like PF08746.6 CDI84399.1 - 1.7 8.7 11.0 3.5 7.7 4.4 2.6 2 0 0 2 2 2 0 RING-like domain Ribosomal_S19e PF01090.14 CDI84400.1 - 2.6e-50 169.5 0.0 2.9e-50 169.3 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e HTH_12 PF08461.5 CDI84400.1 - 0.0014 18.3 0.1 0.0033 17.1 0.0 1.6 1 0 0 1 1 1 1 Ribonuclease R winged-helix domain MarR_2 PF12802.2 CDI84400.1 - 0.057 13.0 0.0 0.62 9.7 0.0 2.5 3 0 0 3 3 3 0 MarR family AP_endonuc_2 PF01261.19 CDI84401.1 - 3.5e-27 95.0 0.0 5.2e-27 94.5 0.0 1.2 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel ABC1 PF03109.11 CDI84402.1 - 2e-32 111.6 0.0 3.8e-32 110.7 0.0 1.4 1 0 0 1 1 1 1 ABC1 family RIO1 PF01163.17 CDI84402.1 - 0.038 13.3 0.0 0.17 11.1 0.0 1.9 2 0 0 2 2 2 0 RIO1 family APH PF01636.18 CDI84402.1 - 0.19 11.4 6.7 0.35 10.5 0.1 3.5 3 1 1 4 4 4 0 Phosphotransferase enzyme family Ribonuc_P_40 PF08584.6 CDI84405.1 - 0.0059 15.6 0.0 0.13 11.2 0.0 2.1 2 0 0 2 2 2 1 Ribonuclease P 40kDa (Rpp40) subunit GSH-S_N PF02951.9 CDI84405.1 - 0.067 13.0 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 Prokaryotic glutathione synthetase, N-terminal domain Oxygenase-NA PF09859.4 CDI84405.1 - 0.078 12.3 0.0 0.18 11.1 0.0 1.5 1 0 0 1 1 1 0 Oxygenase, catalysing oxidative methylation of damaged DNA SbcCD_C PF13558.1 CDI84406.1 - 6.1e-07 29.2 0.0 1.6e-06 27.9 0.0 1.7 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit Metallophos_2 PF12850.2 CDI84406.1 - 0.00033 20.5 0.0 0.0026 17.6 0.0 2.3 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain AAA_15 PF13175.1 CDI84406.1 - 0.0068 15.5 0.0 0.0097 14.9 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain AAA_21 PF13304.1 CDI84406.1 - 0.015 15.3 0.0 0.023 14.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain Metallophos PF00149.23 CDI84406.1 - 0.031 13.6 0.4 0.1 11.9 0.0 1.9 3 0 0 3 3 3 0 Calcineurin-like phosphoesterase SMC_N PF02463.14 CDI84406.1 - 0.04 13.1 0.0 0.059 12.6 0.0 1.3 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain TPR_11 PF13414.1 CDI84407.1 - 4e-17 61.6 1.1 0.00014 21.4 0.0 4.1 3 1 0 4 4 4 3 TPR repeat TPR_2 PF07719.12 CDI84407.1 - 2.3e-14 52.0 5.0 0.0013 18.4 0.0 5.6 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_1 PF00515.23 CDI84407.1 - 8.7e-12 44.1 4.4 0.00041 19.8 0.0 5.4 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_14 PF13428.1 CDI84407.1 - 2.7e-10 39.9 3.3 0.12 13.0 0.1 4.7 3 2 2 5 5 4 3 Tetratricopeptide repeat TPR_8 PF13181.1 CDI84407.1 - 3.4e-10 38.9 0.0 0.0067 16.1 0.0 4.7 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_7 PF13176.1 CDI84407.1 - 1.2e-08 34.1 0.2 0.045 13.5 0.0 4.3 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.1 CDI84407.1 - 1.6e-08 34.9 0.8 0.00039 21.0 0.0 4.1 3 1 2 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.1 CDI84407.1 - 1.6e-08 34.7 0.3 0.11 12.8 0.0 3.3 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_6 PF13174.1 CDI84407.1 - 3.4e-08 33.4 0.4 0.21 12.1 0.0 5.0 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.1 CDI84407.1 - 3.6e-08 33.2 2.6 0.11 12.4 0.0 3.9 3 1 2 5 5 5 4 Tetratricopeptide repeat TPR_17 PF13431.1 CDI84407.1 - 1.1e-06 28.3 0.0 1.3 9.4 0.0 4.8 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_9 PF13371.1 CDI84407.1 - 3.4e-06 26.8 3.3 0.0042 16.8 0.5 3.0 1 1 2 3 3 3 2 Tetratricopeptide repeat Apc3 PF12895.2 CDI84407.1 - 1.9e-05 24.6 0.0 0.0074 16.4 0.0 2.9 2 1 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.1 CDI84407.1 - 0.00039 19.5 0.1 0.0016 17.5 0.1 2.2 1 1 0 1 1 1 1 Tetratricopeptide repeat Peptidase_M14 PF00246.19 CDI84417.1 - 8.6e-12 45.2 0.0 1.5e-11 44.4 0.0 1.3 1 0 0 1 1 1 1 Zinc carboxypeptidase AstE_AspA PF04952.9 CDI84417.1 - 0.08 11.8 0.0 0.16 10.8 0.0 1.5 1 0 0 1 1 1 0 Succinylglutamate desuccinylase / Aspartoacylase family DUF2046 PF09755.4 CDI84418.1 - 0.011 14.6 7.6 0.016 14.1 5.3 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein H4 (DUF2046) BLVR PF06375.6 CDI84418.1 - 0.029 14.2 3.6 0.043 13.6 2.5 1.2 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) Spt5_N PF11942.3 CDI84418.1 - 0.91 10.1 11.7 1.6 9.3 8.1 1.3 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal DUF2215 PF10225.4 CDI84418.1 - 3.1 7.1 4.2 4.7 6.5 2.9 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) Hid1 PF12722.2 CDI84429.1 - 8.1 3.9 47.3 9.2 3.7 32.8 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein AAA_30 PF13604.1 CDI84447.1 - 3.3e-06 26.8 3.6 4.3e-06 26.4 2.5 1.2 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 CDI84447.1 - 0.00021 21.3 0.0 0.00026 21.0 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_7 PF12775.2 CDI84447.1 - 0.0027 16.8 0.0 0.0037 16.3 0.0 1.1 1 0 0 1 1 1 1 P-loop containing dynein motor region D3 AAA_19 PF13245.1 CDI84447.1 - 0.0049 16.5 4.2 0.0085 15.8 2.9 1.4 1 1 0 1 1 1 1 Part of AAA domain AAA_29 PF13555.1 CDI84447.1 - 0.0053 16.2 0.4 0.015 14.8 0.2 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain T2SE PF00437.15 CDI84447.1 - 0.0081 15.0 0.1 0.011 14.6 0.1 1.1 1 0 0 1 1 1 1 Type II/IV secretion system protein DUF815 PF05673.8 CDI84447.1 - 0.0088 14.9 0.2 0.013 14.4 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) DUF853 PF05872.7 CDI84447.1 - 0.013 13.8 0.7 0.013 13.8 0.5 1.4 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF853) Sigma54_activat PF00158.21 CDI84447.1 - 0.032 13.7 0.1 0.047 13.1 0.0 1.2 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_22 PF13401.1 CDI84447.1 - 0.048 13.7 0.0 0.065 13.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.13 CDI84447.1 - 0.058 12.8 1.6 0.062 12.7 0.1 1.8 1 1 0 2 2 2 0 Viral (Superfamily 1) RNA helicase Helicase_RecD PF05127.9 CDI84447.1 - 0.089 12.4 0.4 0.15 11.7 0.3 1.5 1 0 0 1 1 1 0 Helicase Miro PF08477.8 CDI84447.1 - 0.1 13.0 0.2 0.17 12.3 0.1 1.4 1 1 0 1 1 1 0 Miro-like protein DUF87 PF01935.12 CDI84447.1 - 0.15 11.8 0.1 0.15 11.8 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function DUF87 DUF572 PF04502.8 CDI84447.1 - 0.2 10.8 16.0 0.22 10.7 11.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) ORC6 PF05460.8 CDI84447.1 - 5.3 6.0 15.7 6.2 5.8 10.9 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) CAF-1_p150 PF11600.3 CDI84450.1 - 0.28 10.5 54.4 0.0073 15.7 24.5 2.1 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Silic_transp PF03842.8 CDI84450.1 - 1.6 6.7 9.2 0.41 8.6 4.5 1.3 1 1 0 1 1 1 0 Silicon transporter DUF1777 PF08648.7 CDI84450.1 - 3.2 7.4 33.6 6.6 6.4 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1777) MIP-T3 PF10243.4 CDI84450.1 - 3.8 5.8 59.3 0.15 10.4 30.1 2.0 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 SR-25 PF10500.4 CDI84461.1 - 0.0098 15.3 31.7 0.011 15.1 22.0 1.2 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein SprA-related PF12118.3 CDI84461.1 - 2.9 7.1 69.9 3.7 6.7 48.5 1.2 1 0 0 1 1 1 0 SprA-related family Med15 PF09606.5 CDI84461.1 - 2.9 5.9 78.6 3.3 5.8 54.4 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal CDC45 PF02724.9 CDI84461.1 - 5.6 4.8 26.7 6.9 4.5 18.5 1.3 1 0 0 1 1 1 0 CDC45-like protein Med15 PF09606.5 CDI84470.1 - 0.00012 20.4 85.6 0.00012 20.4 59.3 1.1 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal PAT1 PF09770.4 CDI84470.1 - 0.0032 15.7 68.6 0.0036 15.6 47.6 1.1 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 DUF3810 PF12725.2 CDI84470.1 - 0.43 9.4 18.5 0.63 8.8 12.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) LMBR1 PF04791.11 CDI84471.1 - 0.0058 15.2 14.5 0.011 14.3 0.0 2.1 1 1 1 2 2 2 1 LMBR1-like membrane protein SprA-related PF12118.3 CDI84476.1 - 0.0062 15.8 50.1 0.0062 15.8 34.7 7.1 3 1 1 4 4 4 1 SprA-related family FHIPEP PF00771.15 CDI84481.1 - 0.011 14.0 0.7 0.011 14.0 0.5 1.6 1 1 1 2 2 2 0 FHIPEP family DUF966 PF06136.8 CDI84481.1 - 0.013 14.9 14.2 0.018 14.4 9.7 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF966) DUF2489 PF10675.4 CDI84481.1 - 0.023 14.4 0.5 0.045 13.4 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2489) DUF4179 PF13786.1 CDI84481.1 - 0.35 11.1 8.7 1.7 8.9 0.9 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4179) SprA-related PF12118.3 CDI84481.1 - 3 7.0 27.5 8.4 5.6 19.1 1.8 1 1 0 1 1 1 0 SprA-related family INCENP_ARK-bind PF03941.10 CDI84496.1 - 3.2e-07 30.0 0.8 3.2e-07 30.0 0.6 6.2 7 0 0 7 7 7 1 Inner centromere protein, ARK binding region MecA PF05389.7 CDI84496.1 - 0.0014 18.1 2.3 0.0014 18.1 1.6 4.3 3 1 0 3 3 3 1 Negative regulator of genetic competence (MecA) DUF3682 PF12446.3 CDI84496.1 - 0.01 16.1 18.4 0.01 16.1 12.7 7.7 5 2 2 7 7 7 0 Protein of unknown function (DUF3682) FimP PF09766.4 CDI84499.1 - 0.0023 17.0 19.1 0.071 12.1 2.5 2.1 2 0 0 2 2 2 2 Fms-interacting protein TFIIF_beta PF02270.10 CDI84499.1 - 0.033 14.0 11.0 0.042 13.6 7.7 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, beta subunit ATAD4 PF15321.1 CDI84499.1 - 0.087 13.8 11.1 1.2 10.2 2.9 2.2 2 0 0 2 2 2 0 ATPase family AAA domain containing 4 Hist_deacetyl PF00850.14 CDI84499.1 - 0.17 11.1 5.0 0.24 10.6 3.5 1.2 1 0 0 1 1 1 0 Histone deacetylase domain APC_CDC26 PF10471.4 CDI84499.1 - 0.21 12.3 31.9 0.99 10.1 6.1 2.5 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit 1 DUF1764 PF08576.5 CDI84499.1 - 0.28 11.9 11.2 2.6 8.8 0.7 2.2 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF1764) RIC3 PF15361.1 CDI84499.1 - 0.44 10.7 12.4 1.4 9.1 0.3 2.1 2 0 0 2 2 2 0 Resistance to inhibitors of cholinesterase homologue 3 DUF572 PF04502.8 CDI84499.1 - 0.48 9.5 15.1 0.6 9.2 10.5 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) U1snRNP70_N PF12220.3 CDI84499.1 - 0.57 10.5 16.3 1.4 9.2 2.2 2.3 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal Rad60-SLD_2 PF13881.1 CDI84499.1 - 0.59 10.0 7.1 0.8 9.6 0.3 2.2 2 0 0 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like Gly-zipper_OmpA PF13436.1 CDI84499.1 - 0.59 9.8 19.3 0.061 12.9 7.3 2.1 2 0 0 2 2 2 0 Glycine-zipper containing OmpA-like membrane domain dsDNA_bind PF01984.15 CDI84499.1 - 0.73 9.8 38.2 1.1 9.3 10.0 2.2 2 0 0 2 2 2 0 Double-stranded DNA-binding domain CD20 PF04103.10 CDI84499.1 - 0.84 9.5 2.8 7.9 6.3 0.1 2.2 2 0 0 2 2 2 0 CD20-like family Eapp_C PF10238.4 CDI84499.1 - 1 9.2 7.8 5.2 6.9 0.2 2.1 2 0 0 2 2 2 0 E2F-associated phosphoprotein DUF912 PF06024.7 CDI84499.1 - 1 9.4 8.3 6.3 6.9 0.2 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) eIF_4EBP PF05456.6 CDI84499.1 - 1.2 8.8 11.0 1.2 8.8 0.9 2.2 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) DUF3994 PF13159.1 CDI84499.1 - 1.2 9.4 6.2 6.2 7.1 1.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3994) OAD_gamma PF04277.8 CDI84499.1 - 1.4 9.3 8.0 8.8 6.7 3.4 2.3 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain PAT1 PF09770.4 CDI84499.1 - 1.5 6.9 38.9 1.7 6.8 26.9 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF4050 PF13259.1 CDI84499.1 - 1.6 8.6 10.1 5.5 6.9 1.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4050) XRCC4 PF06632.7 CDI84499.1 - 1.7 7.4 13.6 1.5 7.5 4.6 2.0 2 0 0 2 2 2 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 DUF4483 PF14825.1 CDI84499.1 - 2 8.0 18.0 1.5 8.4 0.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4483) DUF2722 PF10846.3 CDI84499.1 - 2.1 7.2 24.4 3.1 6.7 5.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) BRF1 PF07741.8 CDI84499.1 - 2.2 8.5 19.8 2.2 8.5 0.9 2.2 2 0 0 2 2 2 0 Brf1-like TBP-binding domain DUF3506 PF12014.3 CDI84499.1 - 2.4 7.9 6.3 9.1 6.0 0.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3506) FCP1_C PF09309.5 CDI84499.1 - 2.8 7.1 19.9 2.8 7.1 2.8 2.1 2 0 0 2 2 2 0 FCP1, C-terminal CIAPIN1 PF05093.8 CDI84499.1 - 2.9 8.0 11.1 6.4 6.9 2.3 2.2 2 0 0 2 2 2 0 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis TT_ORF2 PF02957.10 CDI84499.1 - 2.9 8.6 9.5 13 6.5 0.4 2.2 2 0 0 2 2 2 0 TT viral ORF2 zf-DHHC PF01529.15 CDI84499.1 - 3.1 7.1 8.3 4.5 6.6 0.4 2.1 2 0 0 2 2 2 0 DHHC palmitoyltransferase Neur_chan_memb PF02932.11 CDI84499.1 - 3.3 7.5 9.3 4.8 6.9 6.5 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region CagX PF03524.10 CDI84499.1 - 4.8 6.3 13.5 4.9 6.3 0.6 2.2 2 0 0 2 2 2 0 Conjugal transfer protein RAB3GAP2_N PF14655.1 CDI84499.1 - 4.9 6.0 19.3 1.1 8.2 2.7 2.1 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Glt_symporter PF03616.9 CDI84499.1 - 5.8 5.3 7.1 2.2 6.6 0.6 2.0 2 0 0 2 2 2 0 Sodium/glutamate symporter Rpp20 PF12328.3 CDI84499.1 - 6.4 6.4 13.2 4.6 6.8 2.3 2.2 2 0 0 2 2 2 0 Rpp20 subunit of nuclear RNase MRP and P EphA2_TM PF14575.1 CDI84499.1 - 6.8 7.1 11.8 9 6.7 1.5 2.4 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain DUF2387 PF09526.5 CDI84499.1 - 7.1 6.6 13.2 0.95 9.4 0.7 2.3 2 0 0 2 2 2 0 Probable metal-binding protein (DUF2387) Conotoxin PF02950.12 CDI84499.1 - 7.6 7.4 10.4 13 6.6 1.0 2.5 2 0 0 2 2 2 0 Conotoxin ERF PF04404.7 CDI84499.1 - 9.6 5.7 27.4 5.6 6.4 6.5 2.2 2 0 0 2 2 2 0 ERF superfamily DUF3484 PF11983.3 CDI84499.1 - 9.7 7.1 22.6 15 6.5 4.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3484) RED_N PF07808.8 CDI84499.1 - 10 5.2 21.3 4 6.5 5.0 2.1 2 0 0 2 2 2 0 RED-like protein N-terminal region HAUS4 PF14735.1 CDI84530.1 - 0.12 11.6 0.2 0.19 10.9 0.1 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 4 Thiolase_N PF00108.18 CDI84531.1 - 1.9e-35 122.1 0.0 1.7e-24 86.2 0.0 2.1 1 1 1 2 2 2 2 Thiolase, N-terminal domain ACP_syn_III PF08545.5 CDI84531.1 - 1e-05 25.1 0.2 0.034 13.8 0.0 2.4 2 0 0 2 2 2 2 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ketoacyl-synt PF00109.21 CDI84531.1 - 5.1e-05 22.8 2.3 0.00089 18.8 0.4 2.5 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Thiolase_C PF02803.13 CDI84532.1 - 3.5e-26 91.0 0.6 1.5e-25 89.0 0.1 1.9 2 0 0 2 2 2 1 Thiolase, C-terminal domain Glyco_trans_4_4 PF13579.1 CDI84532.1 - 0.62 10.1 3.6 0.96 9.5 2.5 1.4 1 1 0 1 1 1 0 Glycosyl transferase 4-like domain Apc15p PF05841.6 CDI84556.1 - 0.02 15.6 21.4 0.11 13.2 7.1 2.2 2 0 0 2 2 2 0 Apc15p protein DUF3299 PF11736.3 CDI84556.1 - 0.027 14.3 12.0 0.25 11.2 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3299) ETRAMP PF09716.5 CDI84556.1 - 0.032 14.1 0.2 0.032 14.1 0.2 2.3 1 1 1 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) 7TM_GPCR_Srw PF10324.4 CDI84556.1 - 0.06 12.4 8.0 0.31 10.1 3.2 2.1 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srw DUF4557 PF15101.1 CDI84556.1 - 0.066 13.0 31.9 0.6 9.9 3.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4557) DUF2946 PF11162.3 CDI84556.1 - 0.071 13.3 0.4 0.071 13.3 0.3 2.5 3 0 0 3 3 2 0 Protein of unknown function (DUF2946) BRF1 PF07741.8 CDI84556.1 - 0.085 13.0 15.5 0.56 10.4 4.1 2.3 2 0 0 2 2 2 0 Brf1-like TBP-binding domain PBP1_TM PF14812.1 CDI84556.1 - 0.17 12.2 5.0 2.3 8.5 0.9 2.8 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF2361 PF10153.4 CDI84556.1 - 0.21 11.8 18.2 1.3 9.2 2.4 2.4 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2361) Glyco_transf_22 PF03901.12 CDI84556.1 - 0.28 10.1 5.6 0.075 12.0 1.9 1.5 1 1 0 1 1 1 0 Alg9-like mannosyltransferase family DUF3899 PF13038.1 CDI84556.1 - 0.33 11.1 7.3 0.76 9.9 0.3 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF3899) E7 PF00527.13 CDI84556.1 - 0.34 11.0 21.0 0.63 10.2 4.6 2.3 2 0 0 2 2 2 0 E7 protein, Early protein Spore_coat_CotO PF14153.1 CDI84556.1 - 0.38 10.1 21.9 0.65 9.4 7.2 2.2 2 0 0 2 2 2 0 Spore coat protein CotO Rxt3 PF08642.5 CDI84556.1 - 0.42 10.8 10.9 1.4 9.2 0.6 2.2 2 0 0 2 2 2 0 Histone deacetylation protein Rxt3 DUF4175 PF13779.1 CDI84556.1 - 0.44 8.1 46.9 0.3 8.7 19.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4175) DUF3357 PF11837.3 CDI84556.1 - 0.5 10.2 12.6 2.9 7.7 0.6 2.8 1 1 2 3 3 3 0 Domain of unknown function (DUF3357) CD20 PF04103.10 CDI84556.1 - 0.58 10.0 19.1 0.4 10.5 4.6 2.5 2 1 1 3 3 3 0 CD20-like family CagX PF03524.10 CDI84556.1 - 0.96 8.6 12.6 3 7.0 3.9 2.1 2 0 0 2 2 2 0 Conjugal transfer protein ARD PF03079.9 CDI84556.1 - 1.6 8.6 9.5 1.9 8.4 0.6 2.1 2 0 0 2 2 2 0 ARD/ARD' family MAT1 PF06391.8 CDI84556.1 - 1.7 8.2 30.1 2.4 7.6 10.6 2.1 2 0 0 2 2 2 0 CDK-activating kinase assembly factor MAT1 DUF1764 PF08576.5 CDI84556.1 - 2 9.2 20.0 3.1 8.6 1.1 2.4 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF1764) PIG-U PF06728.8 CDI84556.1 - 2.4 6.9 8.0 5.2 5.8 5.6 1.7 1 1 0 1 1 1 0 GPI transamidase subunit PIG-U Glt_symporter PF03616.9 CDI84556.1 - 2.5 6.4 9.8 0.78 8.1 1.6 2.1 2 0 0 2 2 2 0 Sodium/glutamate symporter DUF572 PF04502.8 CDI84556.1 - 2.8 7.0 19.5 2.3 7.3 7.9 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF572) EIIBC-GUT_N PF03612.9 CDI84556.1 - 2.8 7.5 16.5 2.4 7.7 5.2 2.1 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus DUF2126 PF09899.4 CDI84556.1 - 2.9 5.8 13.2 1.9 6.4 0.2 2.0 2 0 0 2 2 2 0 Putative amidoligase enzyme (DUF2126) Zip PF02535.17 CDI84556.1 - 3.2 6.6 14.5 0.064 12.2 0.7 2.1 1 1 1 2 2 2 0 ZIP Zinc transporter Transglut_core3 PF13471.1 CDI84556.1 - 3.6 7.4 6.8 8 6.3 0.4 2.4 2 1 0 2 2 2 0 Transglutaminase-like superfamily FlaG PF03646.10 CDI84556.1 - 4.2 7.5 29.5 7.7 6.7 11.6 2.3 2 0 0 2 2 2 0 FlaG protein DUF912 PF06024.7 CDI84556.1 - 4.2 7.4 24.7 0.46 10.5 4.9 3.1 1 1 2 3 3 3 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF3306 PF11748.3 CDI84556.1 - 4.3 8.0 15.1 5.2 7.7 4.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3306) DUF1345 PF07077.6 CDI84556.1 - 4.5 6.7 5.4 7.9 5.9 0.7 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1345) RR_TM4-6 PF06459.7 CDI84556.1 - 4.8 7.0 17.0 3.6 7.4 4.5 2.1 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 RNA_pol_Rbc25 PF08292.7 CDI84556.1 - 5.5 7.2 12.5 7.9 6.7 0.2 2.3 2 0 0 2 2 2 0 RNA polymerase III subunit Rpc25 TerC PF03741.11 CDI84556.1 - 8 5.8 9.7 94 2.3 6.7 2.2 1 1 0 1 1 1 0 Integral membrane protein TerC family Glyco_transf_15 PF01793.11 CDI84556.1 - 8.5 5.2 16.9 2.7 6.8 5.0 2.1 2 0 0 2 2 2 0 Glycolipid 2-alpha-mannosyltransferase DUF3278 PF11683.3 CDI84556.1 - 8.6 6.3 6.8 17 5.3 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3278) PEHE PF15275.1 CDI84556.1 - 9.1 6.7 20.7 2.3 8.6 6.7 2.1 2 0 0 2 2 2 0 PEHE domain DUF1266 PF06889.6 CDI84556.1 - 9.3 6.0 14.6 6.9 6.4 0.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1266) SR-25 PF10500.4 CDI84557.1 - 0.0051 16.3 20.1 0.006 16.0 14.0 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein UvsY PF11056.3 CDI84557.1 - 0.063 13.3 2.9 0.072 13.2 2.0 1.0 1 0 0 1 1 1 0 Recombination, repair and ssDNA binding protein UvsY DUF1675 PF07897.6 CDI84557.1 - 0.9 9.3 12.6 1 9.2 8.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) CDK2AP PF09806.4 CDI84557.1 - 1 9.5 21.9 1.1 9.4 15.1 1.0 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein DUF1635 PF07795.6 CDI84557.1 - 2.9 7.2 13.8 3.3 7.0 9.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) Pap_E4 PF02711.9 CDI84557.1 - 6.3 7.7 15.0 8.8 7.2 10.4 1.3 1 1 0 1 1 1 0 E4 protein Rifin_STEVOR PF02009.11 CDI84558.1 - 0.00039 20.1 0.8 0.00039 20.1 0.6 3.7 2 1 1 3 3 3 1 Rifin/stevor family Pex14_N PF04695.8 CDI84558.1 - 0.035 14.1 1.1 0.035 14.1 0.7 6.3 3 2 1 4 4 4 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Med15 PF09606.5 CDI84558.1 - 1.3 7.1 123.5 0.045 11.9 54.4 2.9 3 0 0 3 3 3 0 ARC105 or Med15 subunit of Mediator complex non-fungal Memo PF01875.12 CDI84559.1 - 2e-38 131.8 0.0 2.2e-38 131.7 0.0 1.0 1 0 0 1 1 1 1 Memo-like protein DUF1079 PF06435.6 CDI84560.1 - 0.066 13.1 4.8 15 5.6 0.0 3.4 3 0 0 3 3 3 0 Repeat of unknown function (DUF1079) DUF3775 PF12616.3 CDI84561.1 - 0.15 11.8 0.1 0.15 11.8 0.1 3.7 4 1 0 4 4 4 0 Protein of unknown function (DUF3775) BRCT PF00533.21 CDI84562.1 - 3.8e-05 23.7 0.0 8e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain Ribosomal_60s PF00428.14 CDI84562.1 - 0.0057 17.0 19.4 0.0057 17.0 13.4 5.6 4 1 2 6 6 6 1 60s Acidic ribosomal protein SR-25 PF10500.4 CDI84562.1 - 0.0074 15.7 20.3 0.0074 15.7 14.1 4.7 2 1 2 4 4 4 3 Nuclear RNA-splicing-associated protein RskA PF10099.4 CDI84562.1 - 0.81 9.3 44.6 0.46 10.2 0.9 3.3 2 1 1 3 3 3 0 Anti-sigma-K factor rskA THRAP3_BCLAF1 PF15440.1 CDI84562.1 - 0.97 8.0 47.6 0.51 8.9 24.5 2.2 2 0 0 2 2 2 0 THRAP3/BCLAF1 family DUF3682 PF12446.3 CDI84563.1 - 0.00092 19.5 17.5 0.0012 19.1 12.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3682) RskA PF10099.4 CDI84563.1 - 0.0026 17.5 4.5 0.0032 17.2 3.1 1.2 1 0 0 1 1 1 1 Anti-sigma-K factor rskA Ribosomal_60s PF00428.14 CDI84563.1 - 0.0037 17.6 16.1 0.0057 17.0 11.1 1.3 1 0 0 1 1 1 1 60s Acidic ribosomal protein Shadoo PF14999.1 CDI84563.1 - 0.055 13.3 5.9 0.063 13.1 4.1 1.1 1 0 0 1 1 1 0 Shadow of prion protein, neuroprotective DUF4544 PF15077.1 CDI84563.1 - 0.072 12.5 4.3 0.079 12.4 3.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4544) MelC1 PF06236.6 CDI84563.1 - 0.25 11.3 11.6 0.29 11.1 8.0 1.1 1 0 0 1 1 1 0 Tyrosinase co-factor MelC1 Spt20 PF12090.3 CDI84563.1 - 0.33 10.2 5.5 0.36 10.1 3.8 1.1 1 0 0 1 1 1 0 Spt20 family PsiA PF06952.6 CDI84563.1 - 0.47 9.4 8.0 0.48 9.4 5.6 1.2 1 0 0 1 1 1 0 PsiA protein Baculo_PP31 PF05311.6 CDI84563.1 - 0.52 9.5 7.3 0.58 9.3 5.1 1.1 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) DUF2217 PF10265.4 CDI84563.1 - 0.56 8.9 4.4 0.62 8.7 3.0 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) PMSI1 PF15322.1 CDI84563.1 - 0.62 9.1 8.9 0.71 8.9 6.2 1.0 1 0 0 1 1 1 0 Protein missing in infertile sperm 1, putative Suf PF05843.9 CDI84563.1 - 0.69 9.5 12.8 0.84 9.3 8.8 1.0 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) R_equi_Vir PF05526.6 CDI84563.1 - 1 8.9 6.4 1.3 8.6 4.4 1.1 1 0 0 1 1 1 0 Rhodococcus equi virulence-associated protein CDK5_activator PF03261.10 CDI84563.1 - 1.3 8.3 7.2 1.4 8.1 5.0 1.0 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein DUF4207 PF13904.1 CDI84563.1 - 1.4 8.2 20.0 1.7 7.9 13.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4207) Med15 PF09606.5 CDI84563.1 - 1.4 7.0 21.9 1.6 6.7 15.2 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal SPX PF03105.14 CDI84563.1 - 1.7 8.3 10.7 2 8.1 7.4 1.0 1 0 0 1 1 1 0 SPX domain MSP1_C PF07462.6 CDI84563.1 - 1.8 6.8 6.1 2.1 6.6 4.2 1.0 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus SprA-related PF12118.3 CDI84563.1 - 2.1 7.5 25.5 2.5 7.3 17.7 1.0 1 0 0 1 1 1 0 SprA-related family DUF3123 PF11321.3 CDI84563.1 - 2.8 8.2 7.6 3.5 7.9 5.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3123) Gag_spuma PF03276.9 CDI84563.1 - 3 6.0 14.5 3.3 5.9 10.1 1.1 1 0 0 1 1 1 0 Spumavirus gag protein RAB3GAP2_N PF14655.1 CDI84563.1 - 5.9 5.7 7.7 6.2 5.7 5.3 1.2 1 1 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus DUF3446 PF11928.3 CDI84564.1 - 1 9.5 18.6 0.17 12.1 6.3 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF3446) HdeA PF06411.6 CDI84564.1 - 1.2 9.2 5.9 4.2 7.4 4.1 2.0 1 0 0 1 1 1 0 HdeA/HdeB family SR-25 PF10500.4 CDI84564.1 - 1.9 7.9 33.0 0.012 15.1 15.4 2.3 1 1 1 2 2 2 0 Nuclear RNA-splicing-associated protein Robl_LC7 PF03259.12 CDI84564.1 - 2.6 7.6 0.0 2.6 7.6 0.0 3.0 2 1 1 3 3 3 0 Roadblock/LC7 domain DUF3636 PF12331.3 CDI84564.1 - 2.6 7.6 9.8 4.3 6.9 6.4 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3636) DUF2407_C PF13373.1 CDI84564.1 - 2.9 7.8 13.6 1.7 8.5 7.6 2.0 1 1 0 1 1 1 0 DUF2407 C-terminal domain PAT1 PF09770.4 CDI84564.1 - 6.4 4.8 62.9 7.4 4.6 43.6 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 MelC1 PF06236.6 CDI84564.1 - 10 6.1 14.7 13 5.8 9.2 1.9 1 1 0 1 1 1 0 Tyrosinase co-factor MelC1 Ribosomal_S8e PF01201.17 CDI84565.1 - 0.31 11.1 3.6 0.37 10.9 2.5 1.2 1 0 0 1 1 1 0 Ribosomal protein S8e FimP PF09766.4 CDI84565.1 - 0.77 8.7 15.7 0.94 8.4 10.9 1.1 1 0 0 1 1 1 0 Fms-interacting protein SAPS PF04499.10 CDI84565.1 - 1.9 7.0 5.9 2 6.9 4.1 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Mitofilin PF09731.4 CDI84565.1 - 9.5 4.7 24.4 11 4.5 16.9 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein DUF4175 PF13779.1 CDI84566.1 - 0.0034 15.1 42.7 0.0038 15.0 29.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4175) CDC45 PF02724.9 CDI84566.1 - 0.011 13.8 10.0 0.01 13.9 6.9 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF822 PF05687.8 CDI84566.1 - 0.022 15.0 6.7 0.025 14.9 4.7 1.2 1 0 0 1 1 1 0 Plant protein of unknown function (DUF822) SAPS PF04499.10 CDI84566.1 - 0.039 12.6 10.6 0.04 12.5 7.4 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein PAT1 PF09770.4 CDI84566.1 - 0.04 12.1 36.4 0.041 12.1 25.2 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TFIIA PF03153.8 CDI84566.1 - 0.043 13.7 27.0 0.046 13.6 18.7 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Spore_coat_CotO PF14153.1 CDI84566.1 - 0.079 12.3 20.5 0.093 12.1 14.2 1.2 1 0 0 1 1 1 0 Spore coat protein CotO DUF4045 PF13254.1 CDI84566.1 - 0.18 11.0 10.4 0.18 11.0 7.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) DUF2126 PF09899.4 CDI84566.1 - 0.24 9.3 9.7 0.26 9.2 6.7 1.0 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) SeqA PF03925.8 CDI84566.1 - 0.24 11.0 10.5 0.28 10.8 7.3 1.2 1 0 0 1 1 1 0 SeqA protein Cellulose_synt PF03552.9 CDI84566.1 - 0.3 9.3 6.8 0.3 9.3 4.7 1.0 1 0 0 1 1 1 0 Cellulose synthase DUF853 PF05872.7 CDI84566.1 - 0.31 9.3 11.5 0.33 9.2 8.0 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) Plasmodium_Vir PF05795.6 CDI84566.1 - 0.35 10.0 3.0 0.35 10.0 2.1 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Hid1 PF12722.2 CDI84566.1 - 0.39 8.3 15.2 0.41 8.2 10.5 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein NARP1 PF12569.3 CDI84566.1 - 0.41 9.3 17.0 0.46 9.1 11.8 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Neur_chan_memb PF02932.11 CDI84566.1 - 0.43 10.4 7.5 0.44 10.3 5.2 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Kei1 PF08552.6 CDI84566.1 - 0.43 10.1 8.4 0.52 9.9 5.8 1.3 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 Peptidase_S15 PF02129.13 CDI84566.1 - 0.45 9.8 14.8 0.52 9.6 10.3 1.2 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) AIF_C PF14721.1 CDI84566.1 - 0.48 10.6 11.5 0.8 9.9 7.9 1.4 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term MRP-S31 PF15433.1 CDI84566.1 - 0.49 9.7 20.7 0.54 9.6 14.4 1.0 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 eIF3_subunit PF08597.5 CDI84566.1 - 0.53 9.8 18.5 0.63 9.5 12.8 1.1 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit AUX_IAA PF02309.11 CDI84566.1 - 0.55 9.9 10.8 0.61 9.7 7.5 1.1 1 0 0 1 1 1 0 AUX/IAA family Pex16 PF08610.5 CDI84566.1 - 0.57 9.1 11.2 0.63 8.9 7.7 1.2 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) CRF1 PF10380.4 CDI84566.1 - 0.59 10.4 7.8 0.74 10.1 5.4 1.3 1 0 0 1 1 1 0 Transcription factor CRF1 FLO_LFY PF01698.11 CDI84566.1 - 0.59 8.9 13.9 0.66 8.7 9.6 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein RNA_pol_Rpb1_5 PF04998.12 CDI84566.1 - 0.6 9.3 7.6 0.62 9.2 5.3 1.1 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 SpoVR PF04293.8 CDI84566.1 - 0.6 8.4 13.7 0.64 8.3 9.5 1.1 1 0 0 1 1 1 0 SpoVR like protein DUF702 PF05142.7 CDI84566.1 - 0.63 10.2 12.8 0.75 9.9 8.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF702) Ctr PF04145.10 CDI84566.1 - 0.65 10.0 7.9 0.79 9.7 5.5 1.4 1 0 0 1 1 1 0 Ctr copper transporter family Peptidase_U57 PF05582.7 CDI84566.1 - 0.69 8.8 12.3 0.83 8.5 8.5 1.1 1 0 0 1 1 1 0 YabG peptidase U57 FYDLN_acid PF09538.5 CDI84566.1 - 0.7 10.5 6.8 0.88 10.1 4.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) CPSF100_C PF13299.1 CDI84566.1 - 0.74 9.9 12.8 0.82 9.8 8.9 1.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal eIF-3_zeta PF05091.7 CDI84566.1 - 0.8 8.2 21.7 0.95 7.9 15.1 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF3492 PF11997.3 CDI84566.1 - 0.81 9.1 10.9 0.88 9.0 7.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3492) Ycf1 PF05758.7 CDI84566.1 - 0.86 7.2 17.9 0.94 7.1 12.4 1.0 1 0 0 1 1 1 0 Ycf1 OmpH PF03938.9 CDI84566.1 - 0.86 9.5 43.0 1.1 9.2 29.8 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) FAM60A PF15396.1 CDI84566.1 - 0.87 9.2 10.4 1 9.0 7.2 1.1 1 0 0 1 1 1 0 Protein Family FAM60A Adaptin_binding PF10199.4 CDI84566.1 - 0.91 9.8 22.5 1.1 9.4 15.6 1.1 1 0 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 Ndc1_Nup PF09531.5 CDI84566.1 - 1.1 7.6 12.6 1.1 7.5 8.7 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup BEX PF04538.7 CDI84566.1 - 1.1 9.5 15.6 1.5 9.0 10.8 1.2 1 0 0 1 1 1 0 Brain expressed X-linked like family Tim54 PF11711.3 CDI84566.1 - 1.1 7.7 10.7 1.2 7.6 7.4 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DUF3474 PF11960.3 CDI84566.1 - 1.1 9.2 3.4 1.4 8.9 2.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3474) LMBR1 PF04791.11 CDI84566.1 - 1.1 7.7 7.6 1.3 7.5 5.3 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein MAT1 PF06391.8 CDI84566.1 - 1.2 8.6 22.9 1.7 8.1 15.9 1.4 1 0 0 1 1 1 0 CDK-activating kinase assembly factor MAT1 DUF3464 PF11947.3 CDI84566.1 - 1.3 8.4 10.9 1.4 8.3 7.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) Band_3_cyto PF07565.8 CDI84566.1 - 1.3 8.4 15.6 1.4 8.3 10.8 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Dynamin_N PF00350.18 CDI84566.1 - 1.4 8.7 7.2 1.8 8.3 5.0 1.3 1 0 0 1 1 1 0 Dynamin family Glyco_transf_15 PF01793.11 CDI84566.1 - 1.4 7.7 13.6 1.6 7.5 9.4 1.1 1 0 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase DDHD PF02862.12 CDI84566.1 - 1.7 8.3 16.6 2.4 7.9 11.5 1.2 1 0 0 1 1 1 0 DDHD domain Hom_end_hint PF05203.11 CDI84566.1 - 1.8 8.2 9.8 2.1 8.0 6.8 1.2 1 0 0 1 1 1 0 Hom_end-associated Hint Mem_trans PF03547.13 CDI84566.1 - 1.8 6.7 7.3 1.8 6.7 5.1 1.1 1 0 0 1 1 1 0 Membrane transport protein DUF4011 PF13195.1 CDI84566.1 - 1.8 8.5 10.7 2.3 8.1 7.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4011) DUF4407 PF14362.1 CDI84566.1 - 1.9 7.4 20.1 1.9 7.3 13.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Draxin PF15550.1 CDI84566.1 - 1.9 8.0 14.0 2.2 7.8 9.7 1.1 1 0 0 1 1 1 0 Draxin PIH1 PF08190.7 CDI84566.1 - 2.1 7.7 20.1 2.3 7.5 13.9 1.1 1 0 0 1 1 1 0 pre-RNA processing PIH1/Nop17 SprA-related PF12118.3 CDI84566.1 - 2.1 7.6 42.9 3.7 6.7 29.8 1.4 1 0 0 1 1 1 0 SprA-related family Med15 PF09606.5 CDI84566.1 - 2.1 6.4 56.2 2.2 6.3 38.9 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Gti1_Pac2 PF09729.4 CDI84566.1 - 2.1 8.1 13.4 2.7 7.8 9.3 1.1 1 0 0 1 1 1 0 Gti1/Pac2 family Bac_luciferase PF00296.15 CDI84566.1 - 2.3 7.2 6.2 3.4 6.6 4.3 1.2 1 0 0 1 1 1 0 Luciferase-like monooxygenase DUF2370 PF10176.4 CDI84566.1 - 2.6 7.3 8.6 3.1 7.0 5.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) BORG_CEP PF14957.1 CDI84566.1 - 2.7 8.9 10.0 3.8 8.4 6.9 1.4 1 0 0 1 1 1 0 Cdc42 effector Folate_carrier PF01770.13 CDI84566.1 - 2.9 6.3 11.3 3.4 6.0 7.8 1.1 1 0 0 1 1 1 0 Reduced folate carrier Peptidase_S49_N PF08496.5 CDI84566.1 - 2.9 7.6 14.9 4.2 7.1 10.3 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Serinc PF03348.10 CDI84566.1 - 2.9 6.4 15.0 3.7 6.1 10.4 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) GPCR_chapero_1 PF11904.3 CDI84566.1 - 3 6.9 14.2 3.4 6.7 9.8 1.1 1 0 0 1 1 1 0 GPCR-chaperone DUF4638 PF15472.1 CDI84566.1 - 3.2 7.2 13.5 3.5 7.1 9.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) Peroxin-13_N PF04088.8 CDI84566.1 - 3.2 7.6 7.5 6.6 6.6 5.2 1.6 1 0 0 1 1 1 0 Peroxin 13, N-terminal region Bud13 PF09736.4 CDI84566.1 - 3.4 7.9 24.5 4.4 7.5 16.9 1.3 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex FemAB PF02388.11 CDI84566.1 - 3.8 6.1 17.3 4.1 5.9 12.0 1.1 1 0 0 1 1 1 0 FemAB family DDRGK PF09756.4 CDI84566.1 - 3.8 6.8 26.6 5.1 6.4 18.4 1.2 1 0 0 1 1 1 0 DDRGK domain Dicty_REP PF05086.7 CDI84566.1 - 4.1 5.0 9.3 4.2 5.0 6.4 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein RR_TM4-6 PF06459.7 CDI84566.1 - 4.3 7.1 18.1 5.1 6.9 12.5 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Asp-B-Hydro_N PF05279.6 CDI84566.1 - 4.3 7.1 15.0 4.8 6.9 10.4 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region G-7-MTase PF12803.2 CDI84566.1 - 4.6 6.2 11.1 5.5 6.0 7.7 1.1 1 0 0 1 1 1 0 mRNA (guanine-7-)methyltransferase (G-7-MTase) FAM176 PF14851.1 CDI84566.1 - 4.9 6.8 10.0 6.1 6.5 6.9 1.2 1 0 0 1 1 1 0 FAM176 family Baculo_PP31 PF05311.6 CDI84566.1 - 5 6.3 15.7 6.5 5.9 10.9 1.1 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) YABBY PF04690.8 CDI84566.1 - 5.2 7.2 10.7 6.3 7.0 7.5 1.2 1 0 0 1 1 1 0 YABBY protein DHHW PF14286.1 CDI84566.1 - 5.5 6.2 13.2 6 6.0 9.1 1.1 1 0 0 1 1 1 0 DHHW protein SID-1_RNA_chan PF13965.1 CDI84566.1 - 5.7 4.9 9.6 5.9 4.9 6.7 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Gag_spuma PF03276.9 CDI84566.1 - 5.8 5.1 32.9 6.9 4.8 22.8 1.1 1 0 0 1 1 1 0 Spumavirus gag protein DUF1800 PF08811.6 CDI84566.1 - 6.9 5.4 20.6 7.3 5.3 14.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1800) Maf1 PF09174.5 CDI84566.1 - 7.3 6.4 10.1 10 5.9 7.0 1.2 1 0 0 1 1 1 0 Maf1 regulator Paramyxo_ncap PF00973.14 CDI84566.1 - 8.2 4.9 15.3 9.2 4.8 10.6 1.0 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Zip PF02535.17 CDI84566.1 - 9.8 5.0 9.3 12 4.7 6.5 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter ADP_ribosyl_GH PF03747.9 CDI84567.1 - 0.033 13.9 4.4 0.039 13.7 3.0 1.1 1 0 0 1 1 1 0 ADP-ribosylglycohydrolase Pilin_PilX PF11530.3 CDI84567.1 - 0.058 13.0 0.0 0.079 12.6 0.0 1.2 1 0 0 1 1 1 0 Minor type IV pilin, PilX FimP PF09766.4 CDI84567.1 - 0.17 10.8 17.4 0.18 10.8 12.0 1.1 1 0 0 1 1 1 0 Fms-interacting protein Dala_Dala_lig_N PF01820.16 CDI84567.1 - 0.3 11.4 5.6 0.35 11.1 3.9 1.1 1 0 0 1 1 1 0 D-ala D-ala ligase N-terminus DUF2950 PF11453.3 CDI84567.1 - 0.47 9.3 10.0 0.54 9.1 6.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2950) Kei1 PF08552.6 CDI84567.1 - 0.76 9.4 7.4 0.93 9.1 5.1 1.1 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 R_equi_Vir PF05526.6 CDI84567.1 - 0.86 9.2 6.8 1 8.9 4.7 1.1 1 0 0 1 1 1 0 Rhodococcus equi virulence-associated protein Suf PF05843.9 CDI84567.1 - 1 8.9 13.0 1 9.0 9.0 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Paf1 PF03985.8 CDI84567.1 - 1.6 7.3 12.7 1.6 7.3 8.8 1.0 1 0 0 1 1 1 0 Paf1 PKI PF02827.11 CDI84567.1 - 2.3 8.3 7.5 2.9 8.0 4.9 1.5 1 1 0 1 1 1 0 cAMP-dependent protein kinase inhibitor Usp PF00582.21 CDI84567.1 - 2.6 8.2 4.5 3.5 7.8 3.1 1.2 1 0 0 1 1 1 0 Universal stress protein family FCP1_C PF09309.5 CDI84567.1 - 2.7 7.2 15.0 2.4 7.4 9.8 1.3 1 1 0 1 1 1 0 FCP1, C-terminal eIF-3_zeta PF05091.7 CDI84567.1 - 3.2 6.2 13.8 3.5 6.1 9.5 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Serinc PF03348.10 CDI84567.1 - 4.2 5.9 8.3 3.8 6.1 5.7 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) DUF3276 PF11680.3 CDI84567.1 - 7 6.4 8.3 11 5.8 5.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3276) Mnd1 PF03962.10 CDI84568.1 - 0.0029 17.2 5.3 0.0029 17.2 3.7 3.1 3 0 0 3 3 3 2 Mnd1 family DUF3881 PF12997.2 CDI84568.1 - 0.039 12.9 0.3 0.039 12.9 0.2 2.6 3 0 0 3 3 3 0 Domain of unknown function, E. rectale Gene description (DUF3881) PAT1 PF09770.4 CDI84568.1 - 0.65 8.1 51.8 0.14 10.3 22.5 2.2 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 Ribosomal_60s PF00428.14 CDI84568.1 - 1.7 9.1 21.2 1.7 9.1 4.6 2.5 2 0 0 2 2 2 0 60s Acidic ribosomal protein DUF4175 PF13779.1 CDI84568.1 - 5.5 4.5 52.7 0.88 7.1 7.6 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4175) DUF1049 PF06305.6 CDI84569.1 - 0.0015 17.9 1.3 0.0057 16.1 0.9 2.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1049) DDE_Tnp_1_2 PF13586.1 CDI84569.1 - 0.073 13.2 0.5 0.18 11.9 0.3 1.7 1 0 0 1 1 1 0 Transposase DDE domain Suf PF05843.9 CDI84569.1 - 0.11 12.2 15.1 0.17 11.5 3.2 2.2 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) SAPS PF04499.10 CDI84569.1 - 0.12 11.0 8.9 0.26 9.8 2.7 2.1 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein PAP1 PF08601.5 CDI84569.1 - 0.17 11.5 23.8 0.31 10.6 10.5 2.2 2 0 0 2 2 2 0 Transcription factor PAP1 Apt1 PF10351.4 CDI84569.1 - 0.19 10.5 12.7 0.52 9.0 6.3 2.1 2 0 0 2 2 2 0 Golgi-body localisation protein domain AAA_23 PF13476.1 CDI84569.1 - 0.25 11.6 7.8 3.3 8.0 3.2 2.1 2 0 0 2 2 2 0 AAA domain Macoilin PF09726.4 CDI84569.1 - 0.62 8.2 28.0 0.19 10.0 12.9 2.3 2 0 0 2 2 2 0 Transmembrane protein DUF775 PF05603.7 CDI84569.1 - 5.4 6.4 18.6 5.3 6.5 3.5 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF775) Apc15p PF05841.6 CDI84569.1 - 5.6 7.7 25.2 1.1 10.0 1.9 3.4 3 0 0 3 3 3 0 Apc15p protein Spt20 PF12090.3 CDI84569.1 - 6.1 6.1 14.3 1.2 8.5 5.4 2.2 2 0 0 2 2 2 0 Spt20 family FimP PF09766.4 CDI84569.1 - 7.2 5.5 18.1 0.7 8.8 6.5 2.1 2 0 0 2 2 2 0 Fms-interacting protein DivIC PF04977.10 CDI84569.1 - 8.7 5.9 14.1 29 4.2 9.8 1.8 1 0 0 1 1 1 0 Septum formation initiator Tetraspannin PF00335.15 CDI84569.1 - 9 5.4 18.8 0.25 10.5 7.2 2.2 2 0 0 2 2 2 0 Tetraspanin family D123 PF07065.9 CDI84570.1 - 0.0036 16.4 0.1 0.0036 16.4 0.0 2.8 2 1 1 3 3 3 1 D123 Ribosomal_60s PF00428.14 CDI84570.1 - 0.0039 17.5 2.2 0.0039 17.5 1.5 3.8 4 0 0 4 4 4 3 60s Acidic ribosomal protein Raftlin PF15250.1 CDI84570.1 - 0.52 8.7 18.4 0.032 12.7 4.2 2.1 2 0 0 2 2 2 0 Raftlin Peptidase_C39 PF03412.10 CDI84571.1 - 8.9e-05 22.3 0.1 0.00021 21.0 0.0 1.7 1 0 0 1 1 1 1 Peptidase C39 family SR-25 PF10500.4 CDI84571.1 - 0.00061 19.3 1.8 0.00061 19.3 1.3 1.0 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Guanylate_cyc_2 PF09778.4 CDI84571.1 - 0.004 16.3 0.4 0.004 16.3 0.3 1.8 2 0 0 2 2 2 1 Guanylylate cyclase DUF912 PF06024.7 CDI84571.1 - 0.056 13.4 4.4 0.072 13.1 3.1 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) FimP PF09766.4 CDI84571.1 - 0.072 12.1 19.5 0.08 12.0 13.5 1.0 1 0 0 1 1 1 0 Fms-interacting protein FAM60A PF15396.1 CDI84571.1 - 0.17 11.5 6.3 0.2 11.4 4.4 1.1 1 0 0 1 1 1 0 Protein Family FAM60A Dala_Dala_lig_N PF01820.16 CDI84571.1 - 0.19 12.0 1.8 0.2 11.9 1.2 1.1 1 0 0 1 1 1 0 D-ala D-ala ligase N-terminus DUF4471 PF14740.1 CDI84571.1 - 0.21 10.7 5.2 0.25 10.5 3.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4471) eIF3_subunit PF08597.5 CDI84571.1 - 0.26 10.8 7.0 0.27 10.7 4.8 1.1 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit Trypan_glycop_C PF10659.4 CDI84571.1 - 0.26 11.5 5.8 0.32 11.2 4.0 1.3 1 0 0 1 1 1 0 Trypanosome variant surface glycoprotein C-terminal domain Glyco_transf_15 PF01793.11 CDI84571.1 - 0.28 10.1 5.7 0.27 10.1 3.9 1.0 1 0 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase BRF1 PF07741.8 CDI84571.1 - 0.28 11.4 7.0 0.32 11.2 4.9 1.1 1 0 0 1 1 1 0 Brf1-like TBP-binding domain Peptidase_S49_N PF08496.5 CDI84571.1 - 0.36 10.5 7.2 0.41 10.4 5.0 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Bud13 PF09736.4 CDI84571.1 - 0.38 11.0 11.8 0.4 10.9 8.2 1.1 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex DUF605 PF04652.11 CDI84571.1 - 0.38 10.0 16.8 0.41 9.9 11.7 1.0 1 0 0 1 1 1 0 Vta1 like Gti1_Pac2 PF09729.4 CDI84571.1 - 0.38 10.5 4.2 0.36 10.6 2.9 1.1 1 0 0 1 1 1 0 Gti1/Pac2 family SAGA-Tad1 PF12767.2 CDI84571.1 - 0.42 10.2 13.2 0.44 10.1 9.1 1.1 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit AIF_C PF14721.1 CDI84571.1 - 0.42 10.8 5.8 0.45 10.7 4.0 1.1 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term DUF4175 PF13779.1 CDI84571.1 - 0.43 8.2 30.9 0.44 8.1 21.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) RIC3 PF15361.1 CDI84571.1 - 0.46 10.7 11.5 0.54 10.4 8.0 1.1 1 0 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 Suf PF05843.9 CDI84571.1 - 0.47 10.1 18.2 0.51 10.0 12.6 1.0 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) FAM176 PF14851.1 CDI84571.1 - 0.58 9.8 4.6 0.64 9.6 3.2 1.1 1 0 0 1 1 1 0 FAM176 family DUF2126 PF09899.4 CDI84571.1 - 0.6 8.0 7.1 0.62 8.0 4.9 1.0 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) FMN_dh PF01070.13 CDI84571.1 - 0.62 8.8 3.8 0.65 8.7 2.6 1.0 1 0 0 1 1 1 0 FMN-dependent dehydrogenase GOLD_2 PF13897.1 CDI84571.1 - 0.65 10.2 2.7 0.67 10.1 1.9 1.1 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking BORG_CEP PF14957.1 CDI84571.1 - 0.68 10.8 7.7 0.78 10.6 5.4 1.1 1 0 0 1 1 1 0 Cdc42 effector OATP PF03137.15 CDI84571.1 - 0.72 7.8 7.3 0.76 7.7 5.1 1.0 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Ctr PF04145.10 CDI84571.1 - 0.74 9.8 4.3 0.73 9.8 3.0 1.2 1 0 0 1 1 1 0 Ctr copper transporter family Tim54 PF11711.3 CDI84571.1 - 0.74 8.3 5.9 0.82 8.1 4.1 1.0 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DUF4557 PF15101.1 CDI84571.1 - 0.75 9.5 18.3 0.79 9.5 12.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) Peptidase_U57 PF05582.7 CDI84571.1 - 0.76 8.6 4.3 0.73 8.7 3.0 1.1 1 0 0 1 1 1 0 YabG peptidase U57 DDHD PF02862.12 CDI84571.1 - 0.79 9.4 8.6 0.78 9.5 5.9 1.0 1 0 0 1 1 1 0 DDHD domain Med15 PF09606.5 CDI84571.1 - 0.82 7.7 38.1 0.8 7.8 26.4 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF913 PF06025.7 CDI84571.1 - 0.91 8.2 5.3 0.96 8.1 3.6 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) FCP1_C PF09309.5 CDI84571.1 - 0.94 8.7 11.7 1.1 8.5 8.1 1.2 1 0 0 1 1 1 0 FCP1, C-terminal MRP-S26 PF14943.1 CDI84571.1 - 1.1 8.8 11.8 1.2 8.6 8.2 1.1 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 HGTP_anticodon2 PF12745.2 CDI84571.1 - 1.1 8.3 8.9 1.2 8.1 6.2 1.0 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs FHIPEP PF00771.15 CDI84571.1 - 1.1 7.4 5.9 1.1 7.5 4.1 1.0 1 0 0 1 1 1 0 FHIPEP family DDRGK PF09756.4 CDI84571.1 - 1.1 8.6 13.1 1.2 8.4 9.1 1.1 1 0 0 1 1 1 0 DDRGK domain PAT1 PF09770.4 CDI84571.1 - 1.1 7.3 30.8 1.2 7.3 21.4 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 EIIBC-GUT_N PF03612.9 CDI84571.1 - 1.1 8.7 7.4 1.3 8.6 5.1 1.1 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus LIM_bind PF01803.11 CDI84571.1 - 1.3 8.0 13.2 1.4 7.9 9.2 1.0 1 0 0 1 1 1 0 LIM-domain binding protein Serinc PF03348.10 CDI84571.1 - 1.3 7.6 9.8 1.5 7.4 6.8 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) CagX PF03524.10 CDI84571.1 - 1.3 8.2 8.5 1.5 8.0 5.9 1.1 1 0 0 1 1 1 0 Conjugal transfer protein CDC45 PF02724.9 CDI84571.1 - 1.4 6.8 8.3 1.4 6.8 5.7 1.0 1 0 0 1 1 1 0 CDC45-like protein RR_TM4-6 PF06459.7 CDI84571.1 - 1.4 8.7 9.9 1.4 8.7 6.9 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Kei1 PF08552.6 CDI84571.1 - 1.5 8.4 5.1 1.6 8.3 3.5 1.1 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 HD-ZIP_N PF04618.7 CDI84571.1 - 1.5 9.3 7.0 1.6 9.2 4.9 1.1 1 0 0 1 1 1 0 HD-ZIP protein N terminus DUF1800 PF08811.6 CDI84571.1 - 1.5 7.6 11.9 1.6 7.5 8.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1800) TFIIA PF03153.8 CDI84571.1 - 1.6 8.5 20.3 1.7 8.4 14.1 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF3464 PF11947.3 CDI84571.1 - 1.7 8.1 10.3 2 7.8 7.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) zf-DHHC PF01529.15 CDI84571.1 - 1.9 7.8 7.5 2.1 7.6 5.2 1.1 1 0 0 1 1 1 0 DHHC palmitoyltransferase Band_3_cyto PF07565.8 CDI84571.1 - 2 7.8 11.8 2.3 7.6 8.1 1.0 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Pex14_N PF04695.8 CDI84571.1 - 2 8.4 20.5 2.4 8.2 14.2 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Baculo_PP31 PF05311.6 CDI84571.1 - 2.2 7.4 9.5 2.5 7.2 6.6 1.1 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) CPSF100_C PF13299.1 CDI84571.1 - 2.4 8.2 7.9 2.7 8.1 5.5 1.1 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal SeqA PF03925.8 CDI84571.1 - 2.7 7.6 9.1 2.8 7.6 6.3 1.1 1 0 0 1 1 1 0 SeqA protein Neur_chan_memb PF02932.11 CDI84571.1 - 2.7 7.8 5.9 2.8 7.7 4.1 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region TMEM51 PF15345.1 CDI84571.1 - 2.7 7.6 12.9 3 7.4 8.9 1.1 1 0 0 1 1 1 0 Transmembrane protein 51 ATAD4 PF15321.1 CDI84571.1 - 2.8 9.0 9.9 3.8 8.5 6.9 1.3 1 0 0 1 1 1 0 ATPase family AAA domain containing 4 OmpH PF03938.9 CDI84571.1 - 2.8 7.8 26.3 2.9 7.8 18.2 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Conotoxin PF02950.12 CDI84571.1 - 3.1 8.6 5.8 4.4 8.1 4.0 1.4 1 0 0 1 1 1 0 Conotoxin Folate_carrier PF01770.13 CDI84571.1 - 3.5 6.0 7.3 3.8 5.9 5.1 1.0 1 0 0 1 1 1 0 Reduced folate carrier eIF-3_zeta PF05091.7 CDI84571.1 - 3.8 6.0 13.6 3.8 6.0 9.4 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF3043 PF11241.3 CDI84571.1 - 4 6.9 7.8 5.1 6.6 5.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) Pex16 PF08610.5 CDI84571.1 - 4.2 6.2 11.8 4 6.3 8.2 1.0 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) Spc7_N PF15402.1 CDI84571.1 - 4.5 5.1 12.0 4.6 5.1 8.3 1.0 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 Activator_LAG-3 PF11498.3 CDI84571.1 - 4.5 5.9 41.0 5 5.7 28.4 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Ycf1 PF05758.7 CDI84571.1 - 4.7 4.7 10.1 4.8 4.7 7.0 1.0 1 0 0 1 1 1 0 Ycf1 DHHW PF14286.1 CDI84571.1 - 4.7 6.4 7.2 4.8 6.3 5.0 1.0 1 0 0 1 1 1 0 DHHW protein DUF775 PF05603.7 CDI84571.1 - 4.8 6.6 12.9 5.6 6.4 8.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF775) G-alpha PF00503.15 CDI84571.1 - 5.3 5.6 12.0 5.8 5.4 8.3 1.0 1 0 0 1 1 1 0 G-protein alpha subunit DUF4407 PF14362.1 CDI84571.1 - 5.3 5.8 12.3 5.6 5.8 8.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) BNIP3 PF06553.7 CDI84571.1 - 5.4 6.3 10.9 6.1 6.1 7.5 1.1 1 0 0 1 1 1 0 BNIP3 Gag_spuma PF03276.9 CDI84571.1 - 6.6 4.9 24.1 6.8 4.8 16.7 1.0 1 0 0 1 1 1 0 Spumavirus gag protein Gryzun PF07919.7 CDI84571.1 - 6.7 4.8 12.2 7.4 4.7 8.4 1.0 1 0 0 1 1 1 0 Gryzun, putative trafficking through Golgi Hid1 PF12722.2 CDI84571.1 - 7.1 4.1 11.2 7.5 4.0 7.8 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Oleosin PF01277.12 CDI84571.1 - 7.2 6.2 6.8 8.5 5.9 4.7 1.2 1 0 0 1 1 1 0 Oleosin RED_N PF07808.8 CDI84571.1 - 7.8 5.6 18.5 9.1 5.4 12.8 1.1 1 0 0 1 1 1 0 RED-like protein N-terminal region DUF3260 PF11658.3 CDI84571.1 - 8.1 4.4 10.3 9.2 4.2 7.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3260) SprA-related PF12118.3 CDI84571.1 - 8.6 5.5 29.5 9.8 5.4 20.5 1.0 1 0 0 1 1 1 0 SprA-related family LMBR1 PF04791.11 CDI84573.1 - 0.25 9.8 6.0 0.25 9.8 4.1 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Mem_trans PF03547.13 CDI84573.1 - 1.9 6.6 5.1 2 6.6 3.6 1.3 1 0 0 1 1 1 0 Membrane transport protein IncA PF04156.9 CDI84574.1 - 3.1e-05 23.6 9.6 3.1e-05 23.6 6.7 11.4 7 2 3 10 10 10 1 IncA protein Activator_LAG-3 PF11498.3 CDI84574.1 - 0.00021 20.2 22.8 0.00021 20.2 15.8 10.1 8 2 1 9 9 9 2 Transcriptional activator LAG-3 DUF1673 PF07895.6 CDI84574.1 - 0.049 13.1 7.2 0.073 12.5 3.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1673) Amino_oxidase PF01593.19 CDI84575.1 - 3.3e-15 56.0 1.4 3.3e-15 56.0 1.0 3.0 2 2 0 2 2 2 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 CDI84575.1 - 3e-14 52.7 0.9 3e-14 52.7 0.6 2.8 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 CDI84575.1 - 0.00027 20.0 0.1 0.00064 18.8 0.1 1.6 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.22 CDI84575.1 - 0.0006 20.1 0.6 0.0018 18.6 0.4 1.9 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.14 CDI84575.1 - 0.014 14.5 0.1 0.014 14.5 0.0 5.5 6 2 2 8 8 8 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Tom22 PF04281.8 CDI84577.1 - 0.0048 16.4 5.7 0.0048 16.4 4.0 2.6 2 1 0 2 2 1 1 Mitochondrial import receptor subunit Tom22 Pox_Ag35 PF03286.9 CDI84577.1 - 0.0053 16.3 4.1 0.0053 16.3 2.9 2.2 2 0 0 2 2 2 1 Pox virus Ag35 surface protein Prothymosin PF03247.9 CDI84577.1 - 0.0091 16.1 14.6 0.0091 16.1 10.1 2.2 2 0 0 2 2 2 1 Prothymosin/parathymosin family Ribosomal_60s PF00428.14 CDI84577.1 - 0.027 14.8 3.8 0.027 14.8 2.6 2.1 2 0 0 2 2 2 0 60s Acidic ribosomal protein FAM176 PF14851.1 CDI84577.1 - 0.064 12.9 21.5 0.059 13.0 4.1 2.2 2 0 0 2 2 2 0 FAM176 family PBP1_TM PF14812.1 CDI84577.1 - 0.14 12.4 27.8 0.43 10.9 4.5 2.2 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal PAT1 PF09770.4 CDI84577.1 - 0.22 9.7 58.5 0.24 9.5 40.6 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 CENP-B_dimeris PF09026.5 CDI84577.1 - 0.67 10.2 21.0 0.73 10.1 6.6 2.2 1 1 1 2 2 2 0 Centromere protein B dimerisation domain FYDLN_acid PF09538.5 CDI84577.1 - 0.72 10.4 22.8 0.24 11.9 5.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) DUF4611 PF15387.1 CDI84577.1 - 1 9.5 23.3 0.15 12.2 5.1 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) YqfQ PF14181.1 CDI84577.1 - 2.1 8.3 34.4 1.6 8.7 9.4 2.2 2 0 0 2 2 2 0 YqfQ-like protein NOA36 PF06524.7 CDI84577.1 - 5.2 6.2 16.1 0.15 11.2 1.3 2.1 2 0 0 2 2 2 0 NOA36 protein Nucleo_P87 PF07267.6 CDI84577.1 - 6.3 5.3 26.8 6.9 5.2 18.6 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Astro_capsid PF03115.9 CDI84577.1 - 6.5 4.8 21.5 7.5 4.6 14.9 1.1 1 0 0 1 1 1 0 Astrovirus capsid protein precursor CobT PF06213.7 CDI84577.1 - 7.1 5.6 32.3 1.5 7.8 8.9 2.1 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT DUF4366 PF14283.1 CDI84577.1 - 8.3 5.7 22.7 0.56 9.5 4.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4366) S-antigen PF05756.6 CDI84577.1 - 8.4 6.4 14.4 0.33 10.9 2.4 2.2 2 0 0 2 2 2 0 S-antigen protein DUF2457 PF10446.4 CDI84577.1 - 8.5 4.9 25.8 0.86 8.2 6.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) TFIIA PF03153.8 CDI84577.1 - 8.8 6.1 47.2 12 5.6 32.7 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit GFP PF01353.17 CDI84577.1 - 8.9 5.6 10.3 11 5.2 7.1 1.2 1 0 0 1 1 1 0 Green fluorescent protein DUF4637 PF15470.1 CDI84577.1 - 9.9 5.7 15.6 1.5 8.4 3.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4637) RskA PF10099.4 CDI84578.1 - 0.0023 17.7 3.8 0.004 16.8 2.6 1.4 1 0 0 1 1 1 1 Anti-sigma-K factor rskA MIP-T3 PF10243.4 CDI84578.1 - 2.6 6.4 75.2 3 6.1 52.1 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DUF1510 PF07423.6 CDI84579.1 - 0.021 14.1 40.5 0.17 11.2 12.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) DUF4355 PF14265.1 CDI84579.1 - 0.037 13.9 10.4 0.065 13.1 7.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4355) PAN_4 PF14295.1 CDI84580.1 - 0.0027 17.3 0.2 0.0055 16.3 0.2 1.4 1 0 0 1 1 1 1 PAN domain Pex14_N PF04695.8 CDI84580.1 - 0.017 15.1 2.0 0.017 15.1 1.4 4.0 2 1 1 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region PAN_2 PF08276.6 CDI84580.1 - 0.022 14.6 1.2 0.022 14.6 0.8 2.3 2 1 0 2 2 2 0 PAN-like domain PLRV_ORF5 PF01690.12 CDI84580.1 - 0.9 8.6 27.6 0.15 11.1 16.0 1.8 2 0 0 2 2 2 0 Potato leaf roll virus readthrough protein LMBR1 PF04791.11 CDI84580.1 - 1.2 7.5 3.2 1.2 7.6 2.2 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF4175 PF13779.1 CDI84580.1 - 1.9 6.0 74.4 0.091 10.4 47.4 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4175) SAGA-Tad1 PF12767.2 CDI84580.1 - 3.2 7.3 30.0 1.3 8.6 17.4 2.2 2 0 0 2 2 2 0 Transcriptional regulator of RNA polII, SAGA, subunit Hist_deacetyl PF00850.14 CDI84580.1 - 4.1 6.6 9.8 26 3.9 0.0 2.4 2 0 0 2 2 2 0 Histone deacetylase domain Ycf1 PF05758.7 CDI84580.1 - 7.1 4.1 22.8 9.8 3.7 15.8 1.2 1 0 0 1 1 1 0 Ycf1 SseC PF04888.7 CDI84581.1 - 4.4e-05 22.9 18.9 5.2e-05 22.7 13.1 1.1 1 0 0 1 1 1 1 Secretion system effector C (SseC) like family DUF3154 PF11351.3 CDI84581.1 - 0.00072 19.2 3.6 0.0011 18.7 2.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3154) BAF1_ABF1 PF04684.8 CDI84581.1 - 0.00074 18.4 25.3 0.00098 18.0 17.5 1.0 1 0 0 1 1 1 1 BAF1 / ABF1 chromatin reorganising factor DUF677 PF05055.7 CDI84581.1 - 0.0091 14.7 1.0 0.01 14.5 0.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF677) FAM176 PF14851.1 CDI84581.1 - 0.0099 15.5 1.4 0.011 15.3 0.9 1.2 1 0 0 1 1 1 1 FAM176 family BRF1 PF07741.8 CDI84581.1 - 0.012 15.7 9.7 0.017 15.3 6.8 1.2 1 0 0 1 1 1 0 Brf1-like TBP-binding domain Gti1_Pac2 PF09729.4 CDI84581.1 - 0.015 15.1 0.5 0.015 15.1 0.3 1.1 1 0 0 1 1 1 0 Gti1/Pac2 family Ycf1 PF05758.7 CDI84581.1 - 0.016 12.9 1.4 0.012 13.3 1.0 1.0 1 0 0 1 1 1 0 Ycf1 COX6A PF02046.10 CDI84581.1 - 0.017 14.9 5.5 0.023 14.6 3.8 1.2 1 0 0 1 1 1 0 Cytochrome c oxidase subunit VIa Med15 PF09606.5 CDI84581.1 - 0.024 12.8 28.4 0.027 12.7 19.7 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF2217 PF10265.4 CDI84581.1 - 0.055 12.2 4.0 0.067 11.9 2.8 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) CDC45 PF02724.9 CDI84581.1 - 0.06 11.3 2.7 0.065 11.2 1.9 1.1 1 0 0 1 1 1 0 CDC45-like protein Anoctamin PF04547.7 CDI84581.1 - 0.063 11.9 0.8 0.065 11.8 0.6 1.1 1 0 0 1 1 1 0 Calcium-activated chloride channel Pex16 PF08610.5 CDI84581.1 - 0.07 12.1 5.8 0.075 12.0 4.0 1.1 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) Auxin_inducible PF02519.9 CDI84581.1 - 0.086 12.9 2.7 0.16 12.0 1.9 1.5 1 0 0 1 1 1 0 Auxin responsive protein Pex14_N PF04695.8 CDI84581.1 - 0.093 12.7 12.9 0.15 12.1 8.9 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF4366 PF14283.1 CDI84581.1 - 0.096 12.0 5.8 0.14 11.6 4.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) Band_3_cyto PF07565.8 CDI84581.1 - 0.097 12.1 9.6 0.11 11.9 6.7 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain DUF912 PF06024.7 CDI84581.1 - 0.1 12.6 4.7 0.17 11.9 3.3 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF2819 PF10995.3 CDI84581.1 - 0.12 11.0 7.2 0.15 10.7 5.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2819) Glyco_transf_15 PF01793.11 CDI84581.1 - 0.15 10.9 5.7 0.15 10.9 4.0 1.1 1 0 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase DUF702 PF05142.7 CDI84581.1 - 0.22 11.7 7.7 0.25 11.5 5.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF702) Neur_chan_memb PF02932.11 CDI84581.1 - 0.22 11.3 0.9 0.2 11.4 0.6 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Dala_Dala_lig_N PF01820.16 CDI84581.1 - 0.41 10.9 2.8 0.5 10.6 1.9 1.2 1 0 0 1 1 1 0 D-ala D-ala ligase N-terminus Sec62 PF03839.11 CDI84581.1 - 0.44 9.9 3.2 0.53 9.6 2.2 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 NARP1 PF12569.3 CDI84581.1 - 0.44 9.2 7.8 0.45 9.2 5.4 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Glyco_transf_6 PF03414.8 CDI84581.1 - 0.5 8.7 4.9 0.75 8.1 3.4 1.3 1 1 0 1 1 1 0 Glycosyltransferase family 6 Kei1 PF08552.6 CDI84581.1 - 0.6 9.7 7.6 0.73 9.4 5.3 1.2 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 DUF2048 PF09752.4 CDI84581.1 - 0.67 8.7 4.8 0.72 8.6 3.3 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2048) DUF4557 PF15101.1 CDI84581.1 - 0.68 9.7 18.8 0.84 9.4 13.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) Tim54 PF11711.3 CDI84581.1 - 0.76 8.2 5.8 0.87 8.1 4.0 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 AUX_IAA PF02309.11 CDI84581.1 - 0.9 9.2 6.0 0.91 9.2 4.1 1.1 1 0 0 1 1 1 0 AUX/IAA family eIF-3_zeta PF05091.7 CDI84581.1 - 0.92 8.0 11.0 1 7.9 7.6 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF3121 PF11319.3 CDI84581.1 - 1 8.8 8.6 1.3 8.4 6.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3121) FimP PF09766.4 CDI84581.1 - 1 8.3 23.6 1.2 8.0 16.3 1.1 1 0 0 1 1 1 0 Fms-interacting protein Packaging_FI PF14000.1 CDI84581.1 - 1.1 9.4 7.1 1.4 9.0 4.9 1.2 1 0 0 1 1 1 0 DNA packaging protein FI Ndc1_Nup PF09531.5 CDI84581.1 - 1.2 7.4 5.1 1.3 7.3 3.5 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup PIH1 PF08190.7 CDI84581.1 - 1.4 8.3 12.5 1.4 8.2 8.6 1.1 1 0 0 1 1 1 0 pre-RNA processing PIH1/Nop17 TFIIA PF03153.8 CDI84581.1 - 1.6 8.5 18.3 1.7 8.4 12.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Suf PF05843.9 CDI84581.1 - 1.6 8.3 14.2 1.9 8.1 9.8 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) PAT1 PF09770.4 CDI84581.1 - 2.1 6.4 25.0 2.2 6.4 17.3 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Gag_spuma PF03276.9 CDI84581.1 - 2.7 6.2 19.9 3.4 5.8 13.8 1.2 1 0 0 1 1 1 0 Spumavirus gag protein MCPVI PF02993.9 CDI84581.1 - 2.9 7.9 10.9 3.7 7.6 7.5 1.1 1 0 0 1 1 1 0 Minor capsid protein VI DUF2126 PF09899.4 CDI84581.1 - 3.7 5.4 6.2 3.4 5.5 4.3 1.1 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) UPF0560 PF10577.4 CDI84581.1 - 4.7 5.3 15.4 5.1 5.2 10.7 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Peroxin-13_N PF04088.8 CDI84581.1 - 5 7.0 6.7 2.3 8.1 3.1 1.6 2 0 0 2 2 2 0 Peroxin 13, N-terminal region DUF2486 PF10667.4 CDI84581.1 - 5.4 7.4 14.6 7.4 7.0 10.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2486) DUF4647 PF15504.1 CDI84581.1 - 9.7 4.9 16.9 11 4.7 11.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4647) DUF1682 PF07946.9 CDI84582.1 - 1.9 7.2 22.5 3.5 6.3 15.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) LMBR1 PF04791.11 CDI84584.1 - 0.02 13.4 0.9 0.032 12.8 0.6 1.5 1 1 0 1 1 1 0 LMBR1-like membrane protein DUF4512 PF14975.1 CDI84584.1 - 2.2 9.1 22.2 0.36 11.6 0.7 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4512) Herpes_DNAp_acc PF04929.7 CDI84585.1 - 0.0046 15.9 0.3 0.0046 15.9 0.2 5.7 1 1 2 3 3 3 1 Herpes DNA replication accessory factor OxoDH_E1alpha_N PF12573.3 CDI84586.1 - 0.022 14.3 0.0 0.045 13.2 0.0 1.5 1 0 0 1 1 1 0 2-oxoisovalerate dehydrogenase E1 alpha subunit N terminal DUF2981 PF11200.3 CDI84587.1 - 5.4 5.9 9.9 10 5.0 6.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) SelB-wing_3 PF09107.6 CDI84588.1 - 0.0071 15.7 0.1 3.7 6.9 0.0 2.4 2 0 0 2 2 2 2 Elongation factor SelB, winged helix SR-25 PF10500.4 CDI84589.1 - 6.8e-05 22.4 60.2 0.017 14.6 17.2 2.5 1 1 0 2 2 2 2 Nuclear RNA-splicing-associated protein DUF4614 PF15391.1 CDI84589.1 - 0.0014 18.4 39.7 0.0094 15.7 10.9 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF4614) APH PF01636.18 CDI84589.1 - 0.26 10.9 9.7 0.047 13.4 0.6 2.4 3 0 0 3 3 3 0 Phosphotransferase enzyme family Apt1 PF10351.4 CDI84589.1 - 4.8 5.9 39.2 0.23 10.2 7.8 2.3 2 0 0 2 2 2 0 Golgi-body localisation protein domain Hex_IIIa PF02455.11 CDI84589.1 - 5.2 5.6 34.1 0.7 8.5 8.3 2.1 2 0 0 2 2 2 0 Hexon-associated protein (IIIa) CAF-1_p150 PF11600.3 CDI84591.1 - 0.0047 16.3 28.8 0.0063 15.9 15.6 2.1 2 0 0 2 2 2 2 Chromatin assembly factor 1 complex p150 subunit, N-terminal Arb1 PF09692.5 CDI84591.1 - 2.5 6.8 12.1 3.7 6.3 8.4 1.3 1 0 0 1 1 1 0 Argonaute siRNA chaperone (ARC) complex subunit Arb1 RAP1 PF07218.6 CDI84591.1 - 3 5.8 10.7 3.8 5.4 7.4 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) PAP1 PF08601.5 CDI84591.1 - 3 7.4 35.3 4.3 6.9 24.5 1.3 1 0 0 1 1 1 0 Transcription factor PAP1 Parvo_coat PF00740.13 CDI84591.1 - 4.8 6.0 32.4 6 5.6 22.4 1.2 1 0 0 1 1 1 0 Parvovirus coat protein VP2 Utp14 PF04615.8 CDI84591.1 - 9.8 4.1 32.5 13 3.7 22.5 1.2 1 0 0 1 1 1 0 Utp14 protein RCR PF12273.3 CDI84594.1 - 0.0025 18.3 25.7 0.0031 18.0 17.8 1.1 1 0 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red Zip PF02535.17 CDI84594.1 - 0.018 14.0 3.3 0.02 13.9 2.3 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Ycf1 PF05758.7 CDI84594.1 - 0.047 11.4 18.1 0.049 11.3 12.5 1.0 1 0 0 1 1 1 0 Ycf1 Gastrin PF00918.12 CDI84594.1 - 0.62 10.8 25.6 0.75 10.6 17.7 1.1 1 0 0 1 1 1 0 Gastrin/cholecystokinin family DUF4220 PF13968.1 CDI84594.1 - 0.79 8.7 8.0 0.93 8.5 5.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4220) KASH PF10541.4 CDI84594.1 - 1 9.2 4.7 1.5 8.7 3.3 1.2 1 0 0 1 1 1 0 Nuclear envelope localisation domain SID-1_RNA_chan PF13965.1 CDI84594.1 - 1 7.4 12.2 1.1 7.3 8.5 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 ExbD PF02472.11 CDI84594.1 - 1.2 9.1 12.3 1.9 8.4 8.5 1.3 1 0 0 1 1 1 0 Biopolymer transport protein ExbD/TolR Cytochrom_B_N PF00033.14 CDI84594.1 - 1.8 7.8 5.7 6.7 6.0 3.9 1.8 1 1 0 1 1 1 0 Cytochrome b(N-terminal)/b6/petB DUF3260 PF11658.3 CDI84594.1 - 2.2 6.3 16.8 2.7 6.0 11.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3260) Herpes_UL87 PF03043.9 CDI84594.1 - 2.5 6.3 12.3 2.6 6.3 8.6 1.0 1 0 0 1 1 1 0 Herpesvirus UL87 family DUF3357 PF11837.3 CDI84594.1 - 3.7 7.4 11.3 2.7e+02 1.4 7.8 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF3357) US2 PF02476.10 CDI84594.1 - 3.8 8.0 8.1 4.6 7.7 5.6 1.1 1 0 0 1 1 1 0 US2 family Herpes_DNAp_acc PF04929.7 CDI84594.1 - 6.4 5.6 18.7 7.2 5.4 13.0 1.0 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Tetraspannin PF00335.15 CDI84594.1 - 6.6 5.9 12.2 9 5.4 8.4 1.3 1 0 0 1 1 1 0 Tetraspanin family DUF4175 PF13779.1 CDI84594.1 - 7.5 4.1 53.1 8.6 3.9 36.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) RNA_pol_Rpb1_5 PF04998.12 CDI84594.1 - 8.7 5.5 12.6 10 5.2 8.7 1.0 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 Mem_trans PF03547.13 CDI84594.1 - 8.9 4.4 10.6 10 4.3 7.3 1.1 1 0 0 1 1 1 0 Membrane transport protein IncFII_repA PF02387.10 CDI84594.1 - 9.1 5.3 19.2 9.4 5.2 13.3 1.0 1 0 0 1 1 1 0 IncFII RepA protein family Cwf_Cwc_15 PF04889.7 CDI84595.1 - 0.043 13.5 0.0 0.072 12.7 0.0 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Macoilin PF09726.4 CDI84595.1 - 0.51 8.5 12.2 0.7 8.0 8.5 1.3 1 0 0 1 1 1 0 Transmembrane protein CAF-1_p150 PF11600.3 CDI84595.1 - 1 8.6 15.3 1.6 8.0 10.6 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal APC_CDC26 PF10471.4 CDI84595.1 - 1.5 9.6 12.8 1.5 9.6 2.3 2.8 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit 1 DUF4614 PF15391.1 CDI84595.1 - 1.6 8.5 17.2 0.017 14.8 6.4 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4614) SR-25 PF10500.4 CDI84595.1 - 3.9 6.8 33.7 2.3 7.6 10.1 2.3 1 1 1 2 2 2 0 Nuclear RNA-splicing-associated protein DUF1117 PF06547.7 CDI84595.1 - 4.2 7.4 16.9 1.3 9.1 8.2 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF1117) SR-25 PF10500.4 CDI84596.1 - 0.00018 21.0 12.5 0.00018 21.0 8.7 3.1 2 1 0 2 2 2 1 Nuclear RNA-splicing-associated protein Activator_LAG-3 PF11498.3 CDI84596.1 - 0.0069 15.1 32.8 0.011 14.4 9.7 2.4 2 0 0 2 2 2 2 Transcriptional activator LAG-3 RAB3GAP2_N PF14655.1 CDI84596.1 - 0.048 12.6 16.4 0.5 9.3 1.7 2.2 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus DUF3801 PF12687.2 CDI84596.1 - 0.06 12.9 8.7 1.3 8.5 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3801) FimP PF09766.4 CDI84596.1 - 0.17 10.9 19.4 0.63 9.0 2.7 2.2 2 0 0 2 2 2 0 Fms-interacting protein LIM_bind PF01803.11 CDI84596.1 - 0.58 9.2 17.3 0.1 11.6 3.2 2.3 2 0 0 2 2 2 0 LIM-domain binding protein LMBR1 PF04791.11 CDI84596.1 - 0.86 8.1 5.8 1.2 7.6 0.2 2.1 2 0 0 2 2 2 0 LMBR1-like membrane protein Baculo_PP31 PF05311.6 CDI84596.1 - 1.1 8.5 16.9 0.17 11.1 2.2 2.4 2 0 0 2 2 2 0 Baculovirus 33KDa late protein (PP31) Corona_nucleoca PF00937.13 CDI84596.1 - 2.6 6.9 38.4 2.2 7.1 6.1 2.4 2 0 0 2 2 2 0 Coronavirus nucleocapsid protein Apt1 PF10351.4 CDI84596.1 - 6.1 5.5 23.8 0.12 11.2 2.4 2.1 2 0 0 2 2 2 0 Golgi-body localisation protein domain Rpp20 PF12328.3 CDI84598.1 - 0.0049 16.5 2.8 0.015 14.9 2.0 1.8 1 0 0 1 1 1 1 Rpp20 subunit of nuclear RNase MRP and P SeqA PF03925.8 CDI84598.1 - 0.022 14.4 2.5 0.079 12.6 1.8 1.9 1 0 0 1 1 1 0 SeqA protein PAP1 PF08601.5 CDI84598.1 - 0.048 13.3 16.6 0.1 12.2 4.4 2.4 2 0 0 2 2 2 0 Transcription factor PAP1 Miff PF05644.6 CDI84598.1 - 0.48 10.0 5.4 1.6 8.3 0.4 2.4 2 0 0 2 2 2 0 Mitochondrial and peroxisomal fission factor Mff Band_3_cyto PF07565.8 CDI84598.1 - 0.52 9.7 5.2 0.63 9.5 1.0 2.2 2 0 0 2 2 2 0 Band 3 cytoplasmic domain DUF3365 PF11845.3 CDI84598.1 - 0.95 9.2 7.2 5.4 6.8 1.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3365) Suf PF05843.9 CDI84598.1 - 0.96 9.1 7.3 0.27 10.9 1.9 2.1 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) Hid1 PF12722.2 CDI84598.1 - 2.8 5.5 11.5 3.9 5.0 0.3 2.1 2 0 0 2 2 2 0 High-temperature-induced dauer-formation protein Gti1_Pac2 PF09729.4 CDI84598.1 - 6.9 6.5 10.6 6.4 6.6 1.0 2.4 2 0 0 2 2 2 0 Gti1/Pac2 family Nsp1_C PF05064.8 CDI84599.1 - 0.18 11.4 3.0 0.26 10.9 2.1 1.3 1 0 0 1 1 1 0 Nsp1-like C-terminal region KIAA1328 PF15369.1 CDI84599.1 - 0.55 9.9 6.4 0.61 9.8 4.4 1.0 1 0 0 1 1 1 0 Uncharacterised protein KIAA1328 Mcm10 PF09332.6 CDI84599.1 - 3.6 6.8 15.8 4.1 6.6 10.9 1.0 1 0 0 1 1 1 0 Mcm10 replication factor SGT1 PF07093.6 CDI84601.1 - 5.8e-06 24.9 13.7 5.8e-06 24.9 9.5 1.8 2 0 0 2 2 2 1 SGT1 protein SprA-related PF12118.3 CDI84601.1 - 0.00063 19.1 28.3 0.00063 19.1 19.6 3.1 3 0 0 3 3 3 1 SprA-related family Ycf1 PF05758.7 CDI84601.1 - 0.17 9.5 31.2 0.29 8.8 9.2 2.1 2 0 0 2 2 2 0 Ycf1 DUF3993 PF13158.1 CDI84602.1 - 0.081 12.7 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3993) LCCL PF03815.14 CDI84603.1 - 5.3e-19 68.0 0.0 8.1e-19 67.4 0.0 1.2 1 0 0 1 1 1 1 LCCL domain LCCL PF03815.14 CDI84604.1 - 4.8e-16 58.5 0.1 1.3e-12 47.4 0.0 2.7 2 0 0 2 2 2 2 LCCL domain SRCR PF00530.13 CDI84604.1 - 9.5e-06 25.8 0.3 0.033 14.5 0.0 2.6 2 0 0 2 2 2 2 Scavenger receptor cysteine-rich domain Ribosomal_L32e PF01655.13 CDI84605.1 - 8.2e-45 151.3 3.0 1.1e-44 151.0 2.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L32 TFIIA PF03153.8 CDI84606.1 - 0.54 10.1 26.5 0.73 9.6 18.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit IncA PF04156.9 CDI84607.1 - 0.00026 20.6 8.7 0.00026 20.6 6.1 5.6 4 1 0 4 4 4 1 IncA protein Mucin PF01456.12 CDI84607.1 - 0.00093 18.9 22.5 0.00093 18.9 15.6 5.5 4 1 1 5 5 5 1 Mucin-like glycoprotein N6_N4_Mtase PF01555.13 CDI84607.1 - 4.4 6.7 7.1 54 3.1 0.1 3.9 2 2 0 3 3 3 0 DNA methylase zf-DHHC PF01529.15 CDI84607.1 - 5.6 6.3 26.7 0.99 8.7 0.0 5.2 5 0 0 5 5 5 0 DHHC palmitoyltransferase Asp_protease_2 PF13650.1 CDI84608.1 - 1.4e-06 28.7 0.0 3.2e-06 27.5 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 CDI84608.1 - 0.00017 21.3 0.0 0.00042 20.0 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease DUF630 PF04783.7 CDI84609.1 - 0.081 12.8 4.1 0.15 11.9 1.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF630) Med15 PF09606.5 CDI84609.1 - 0.085 11.0 47.9 0.13 10.3 33.2 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF1669 PF07894.7 CDI84609.1 - 0.16 11.1 7.3 0.24 10.5 5.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1669) DUF2126 PF09899.4 CDI84609.1 - 0.17 9.8 12.6 0.21 9.5 8.7 1.0 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) Sporozoite_P67 PF05642.6 CDI84609.1 - 0.48 8.2 3.2 0.59 7.9 2.2 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen CDV3 PF15359.1 CDI84609.1 - 0.81 9.7 7.2 0.039 14.0 1.1 1.7 2 0 0 2 2 2 0 Carnitine deficiency-associated protein 3 Amidase PF01425.16 CDI84609.1 - 1.3 7.7 7.2 0.11 11.2 1.5 1.6 1 1 1 2 2 2 0 Amidase SPX PF03105.14 CDI84609.1 - 1.5 8.5 14.6 2.3 7.9 10.1 1.4 1 0 0 1 1 1 0 SPX domain Herpes_UL87 PF03043.9 CDI84609.1 - 6.7 4.9 11.2 7.5 4.8 7.8 1.2 1 0 0 1 1 1 0 Herpesvirus UL87 family Hist_deacetyl PF00850.14 CDI84609.1 - 7.1 5.8 11.2 13 4.9 7.7 1.4 1 1 0 1 1 1 0 Histone deacetylase domain Hid1 PF12722.2 CDI84609.1 - 7.5 4.0 16.0 10 3.6 11.1 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Bul1_C PF04426.7 CDI84610.1 - 1.9 7.5 28.3 2.3 7.3 19.6 1.0 1 0 0 1 1 1 0 Bul1 C terminus DUF2859 PF11072.3 CDI84611.1 - 0.0012 18.3 10.3 0.048 13.1 1.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF2859) DUF2272 PF10030.4 CDI84611.1 - 0.075 12.4 5.8 0.83 9.0 0.2 2.1 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2272) Rtf2 PF04641.7 CDI84611.1 - 0.09 11.9 8.0 0.099 11.8 5.5 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger DUF4512 PF14975.1 CDI84611.1 - 0.74 10.6 5.6 1.2 10.0 3.8 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4512) A2M_N_2 PF07703.9 CDI84611.1 - 1.9 8.3 9.6 12 5.7 6.7 1.9 1 1 0 1 1 1 0 Alpha-2-macroglobulin family N-terminal region DUF4602 PF15375.1 CDI84611.1 - 2.6 8.0 16.5 2.4 8.2 2.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4602) Presenilin PF01080.12 CDI84611.1 - 4.2 6.0 7.3 4.7 5.9 5.1 1.0 1 0 0 1 1 1 0 Presenilin Zip PF02535.17 CDI84611.1 - 4.3 6.2 5.5 5.1 6.0 3.8 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter ORC5_C PF14630.1 CDI84611.1 - 4.8 6.5 15.4 1.6 8.1 2.0 2.0 1 1 1 2 2 2 0 Origin recognition complex (ORC) subunit 5 C-terminus DUF4407 PF14362.1 CDI84611.1 - 6.1 5.7 15.5 8.6 5.2 10.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) RAB3GAP2_N PF14655.1 CDI84611.1 - 6.3 5.6 21.3 2.2 7.2 4.1 2.1 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus OPA3 PF07047.7 CDI84611.1 - 6.6 6.5 13.3 4.8 6.9 1.8 2.1 2 0 0 2 2 2 0 Optic atrophy 3 protein (OPA3) DUF4045 PF13254.1 CDI84611.1 - 7.4 5.7 11.8 7.8 5.6 8.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) AAA_11 PF13086.1 CDI84611.1 - 7.5 6.0 12.6 8.5 5.8 8.7 1.2 1 0 0 1 1 1 0 AAA domain ORC6 PF05460.8 CDI84612.1 - 0.17 10.9 23.1 0.2 10.7 16.0 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) DUF936 PF06075.7 CDI84612.1 - 0.26 10.1 24.6 0.33 9.8 17.0 1.0 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) DUF4551 PF15087.1 CDI84612.1 - 3.9 5.7 24.4 4.9 5.3 16.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Ebola_NP PF05505.7 CDI84612.1 - 7 4.5 17.6 8.3 4.3 12.2 1.0 1 0 0 1 1 1 0 Ebola nucleoprotein DUF4045 PF13254.1 CDI84613.1 - 6.5 5.9 37.5 8.1 5.6 26.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) DUF572 PF04502.8 CDI84613.1 - 6.7 5.8 38.9 8 5.5 27.0 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF572) BAF1_ABF1 PF04684.8 CDI84614.1 - 0.86 8.3 55.4 0.11 11.3 26.2 2.4 1 1 1 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor DUF2899 PF11449.3 CDI84614.1 - 2 7.5 7.1 4.4 6.4 4.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2899) Actin PF00022.14 CDI84618.1 - 2.6e-05 22.8 0.8 0.00024 19.6 0.3 2.2 2 1 0 2 2 2 1 Actin Med15 PF09606.5 CDI84618.1 - 0.03 12.5 18.5 0.037 12.2 12.8 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Protamine_P2 PF00841.14 CDI84618.1 - 0.16 12.5 6.3 0.31 11.6 4.4 1.5 1 0 0 1 1 1 0 Sperm histone P2 Med3 PF11593.3 CDI84618.1 - 0.36 10.0 10.7 0.49 9.5 7.4 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DUF2203 PF09969.4 CDI84618.1 - 0.46 10.6 4.6 0.81 9.9 3.2 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) FCP1_C PF09309.5 CDI84618.1 - 0.48 9.6 4.3 0.69 9.1 3.0 1.2 1 0 0 1 1 1 0 FCP1, C-terminal Activator_LAG-3 PF11498.3 CDI84618.1 - 3.4 6.3 21.1 4.2 6.0 14.6 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 TSA PF03249.8 CDI84618.1 - 7.4 4.9 16.0 9.8 4.5 11.1 1.2 1 0 0 1 1 1 0 Type specific antigen Suf PF05843.9 CDI84619.1 - 0.036 13.7 8.2 0.038 13.7 5.7 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) FimP PF09766.4 CDI84619.1 - 0.1 11.6 9.3 0.11 11.5 6.4 1.1 1 0 0 1 1 1 0 Fms-interacting protein Med15 PF09606.5 CDI84619.1 - 1.7 6.7 40.8 2.2 6.3 28.3 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal CRF1 PF10380.4 CDI84622.1 - 0.0075 16.5 0.2 0.0075 16.5 0.1 4.8 4 1 0 4 4 4 2 Transcription factor CRF1 MIP-T3 PF10243.4 CDI84623.1 - 1.8e-06 26.7 32.7 1.8e-06 26.7 22.7 3.4 3 1 0 4 4 4 2 Microtubule-binding protein MIP-T3 Abhydrolase_5 PF12695.2 CDI84623.1 - 0.45 10.2 18.7 25 4.5 12.9 2.8 1 1 0 1 1 1 0 Alpha/beta hydrolase family LMBR1 PF04791.11 CDI84623.1 - 4.9 5.6 15.8 0.031 12.8 3.5 2.2 2 0 0 2 2 2 0 LMBR1-like membrane protein MarC PF01914.12 CDI84624.1 - 0.0018 17.3 5.7 0.18 10.9 0.4 2.0 1 1 1 2 2 2 2 MarC family integral membrane protein GDA1_CD39 PF01150.12 CDI84624.1 - 0.011 14.2 13.7 0.058 11.8 9.5 1.8 1 1 0 1 1 1 0 GDA1/CD39 (nucleoside phosphatase) family AIF_C PF14721.1 CDI84624.1 - 0.072 13.3 6.4 0.083 13.1 4.4 1.1 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Lipoprotein_X PF03305.8 CDI84624.1 - 0.1 11.9 5.9 0.11 11.8 4.1 1.0 1 0 0 1 1 1 0 Mycoplasma MG185/MG260 protein U3_assoc_6 PF08640.6 CDI84624.1 - 0.12 12.1 5.1 2.2 8.0 0.3 2.0 1 1 1 2 2 2 0 U3 small nucleolar RNA-associated protein 6 MACPF PF01823.14 CDI84624.1 - 0.25 10.9 3.2 0.29 10.7 2.2 1.0 1 0 0 1 1 1 0 MAC/Perforin domain DRY_EERY PF09750.4 CDI84624.1 - 0.26 11.3 8.7 0.33 11.0 6.1 1.1 1 0 0 1 1 1 0 Alternative splicing regulator Peptidase_U57 PF05582.7 CDI84624.1 - 0.28 10.1 7.2 0.29 10.0 5.0 1.0 1 0 0 1 1 1 0 YabG peptidase U57 DALR_2 PF09190.6 CDI84624.1 - 0.31 11.3 3.2 9.9 6.5 0.2 2.1 1 1 1 2 2 2 0 DALR domain RP-C_C PF11800.3 CDI84624.1 - 0.45 10.1 7.8 0.52 9.9 5.4 1.1 1 0 0 1 1 1 0 Replication protein C C-terminal region Afi1 PF07792.7 CDI84624.1 - 0.52 10.3 8.3 0.64 10.0 5.8 1.2 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking UPF0515 PF15135.1 CDI84624.1 - 0.55 9.2 3.2 0.6 9.1 2.2 1.0 1 0 0 1 1 1 0 Uncharacterised protein UPF0515 G-7-MTase PF12803.2 CDI84624.1 - 0.59 9.2 4.3 0.6 9.1 3.0 1.0 1 0 0 1 1 1 0 mRNA (guanine-7-)methyltransferase (G-7-MTase) Chloroa_b-bind PF00504.16 CDI84624.1 - 0.78 9.9 2.9 0.86 9.8 2.0 1.1 1 0 0 1 1 1 0 Chlorophyll A-B binding protein SpoIIP PF07454.6 CDI84624.1 - 0.97 8.5 8.4 1.1 8.3 5.8 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) SpoVR PF04293.8 CDI84624.1 - 0.98 7.7 9.5 1 7.6 6.6 1.0 1 0 0 1 1 1 0 SpoVR like protein DUF3464 PF11947.3 CDI84624.1 - 1 8.8 6.6 1.3 8.4 4.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) FLO_LFY PF01698.11 CDI84624.1 - 1.1 7.9 8.9 1.2 7.9 6.2 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein DUF2126 PF09899.4 CDI84624.1 - 1.1 7.1 5.9 1.3 6.9 4.1 1.0 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) DUF853 PF05872.7 CDI84624.1 - 1.2 7.4 9.6 1.5 7.1 6.7 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) PAT1 PF09770.4 CDI84624.1 - 1.5 6.9 26.6 1.8 6.7 18.5 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF342 PF03961.8 CDI84624.1 - 1.6 7.0 8.5 1.8 6.9 5.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Peptidase_S15 PF02129.13 CDI84624.1 - 2 7.7 7.1 2.2 7.6 4.9 1.0 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) DUF243 PF03103.12 CDI84624.1 - 2 8.5 15.9 9.7 6.3 11.0 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF243) Neur_chan_memb PF02932.11 CDI84624.1 - 2 8.2 6.3 2.6 7.8 4.4 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region SprA-related PF12118.3 CDI84624.1 - 2.5 7.3 26.1 2.7 7.2 18.1 1.1 1 0 0 1 1 1 0 SprA-related family OATP PF03137.15 CDI84624.1 - 3 5.7 6.6 3.6 5.5 4.6 1.2 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Reo_P9 PF06043.6 CDI84624.1 - 3.6 6.5 6.7 6.7 5.6 4.6 1.5 1 1 0 1 1 1 0 Reovirus P9-like family FAM60A PF15396.1 CDI84624.1 - 4.3 7.0 6.4 5 6.8 4.4 1.1 1 0 0 1 1 1 0 Protein Family FAM60A PIG-S PF10510.4 CDI84624.1 - 4.4 5.8 12.7 5.2 5.6 8.8 1.0 1 0 0 1 1 1 0 Phosphatidylinositol-glycan biosynthesis class S protein DDHD PF02862.12 CDI84624.1 - 4.6 6.9 8.8 5.5 6.7 6.1 1.1 1 0 0 1 1 1 0 DDHD domain Methyltransf_11 PF08241.7 CDI84624.1 - 4.9 7.7 6.1 19 5.7 0.5 2.0 1 1 1 2 2 2 0 Methyltransferase domain MNNL PF07657.8 CDI84624.1 - 5 7.1 7.0 13 5.7 0.6 2.0 1 1 1 2 2 2 0 N terminus of Notch ligand DOR PF14839.1 CDI84624.1 - 5.1 6.7 16.3 5.5 6.6 11.3 1.0 1 0 0 1 1 1 0 DOR family PWI PF01480.12 CDI84624.1 - 5.7 7.1 8.2 6.2 7.0 0.6 2.1 1 1 1 2 2 2 0 PWI domain Calici_coat_C PF08435.6 CDI84624.1 - 6.1 6.0 8.5 7 5.8 5.9 1.0 1 0 0 1 1 1 0 Calicivirus coat protein C-terminal 5_nucleotid PF05761.9 CDI84624.1 - 7.2 5.0 10.3 8.5 4.7 7.1 1.0 1 0 0 1 1 1 0 5' nucleotidase family Hid1 PF12722.2 CDI84624.1 - 7.5 4.0 11.4 8.5 3.9 7.9 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF2072 PF09845.4 CDI84624.1 - 7.9 6.4 7.4 10 6.0 5.1 1.2 1 0 0 1 1 1 0 Zn-ribbon containing protein (DUF2072) Peroxin-13_N PF04088.8 CDI84624.1 - 8.7 6.2 9.7 37 4.2 6.7 1.8 1 1 0 1 1 1 0 Peroxin 13, N-terminal region Vps39_1 PF10366.4 CDI84624.1 - 8.9 6.3 13.7 8.9 6.3 2.6 2.1 1 1 1 2 2 2 0 Vacuolar sorting protein 39 domain 1 Sedlin_N PF04628.8 CDI84624.1 - 9.5 6.0 7.7 13 5.6 5.3 1.3 1 1 0 1 1 1 0 Sedlin, N-terminal conserved region GDA1_CD39 PF01150.12 CDI84625.1 - 9.4e-07 27.6 0.4 9.4e-07 27.6 0.3 1.5 1 1 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Nucleoporin_N PF08801.6 CDI84625.1 - 0.06 12.0 6.7 0.072 11.8 4.6 1.1 1 0 0 1 1 1 0 Nup133 N terminal like Herpes_UL87 PF03043.9 CDI84625.1 - 0.16 10.2 10.1 0.21 9.9 7.0 1.0 1 0 0 1 1 1 0 Herpesvirus UL87 family Herpes_DNAp_acc PF04929.7 CDI84625.1 - 0.79 8.6 12.8 0.92 8.4 8.9 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor PGA_cap PF09587.5 CDI84625.1 - 1.2 8.4 8.0 2.5 7.3 5.5 1.5 1 1 0 1 1 1 0 Bacterial capsule synthesis protein PGA_cap PSK PF06404.7 CDI84625.1 - 1.4 9.7 15.3 0.35 11.6 0.5 2.5 2 0 0 2 2 2 0 Phytosulfokine precursor protein (PSK) FimP PF09766.4 CDI84625.1 - 1.5 7.7 37.3 0.14 11.1 4.3 2.1 2 0 0 2 2 2 0 Fms-interacting protein Med15 PF09606.5 CDI84625.1 - 1.9 6.5 58.5 2.4 6.2 40.6 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Hid1 PF12722.2 CDI84625.1 - 3.6 5.1 16.2 4.3 4.8 11.2 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF3592 PF12158.3 CDI84625.1 - 3.7 7.3 9.7 6.3 6.5 6.7 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3592) BNR_3 PF13859.1 CDI84625.1 - 3.8 6.4 9.1 5.4 6.0 6.3 1.2 1 0 0 1 1 1 0 BNR repeat-like domain DUF4512 PF14975.1 CDI84625.1 - 6.1 7.7 10.7 20 6.1 7.4 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4512) Presenilin PF01080.12 CDI84625.1 - 6.2 5.5 12.8 12 4.5 8.9 1.5 1 0 0 1 1 1 0 Presenilin DUF1682 PF07946.9 CDI84625.1 - 8 5.2 16.6 11 4.7 11.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) 7tm_7 PF08395.7 CDI84626.1 - 0.0017 17.4 1.0 0.0017 17.4 0.7 3.4 4 1 1 5 5 5 1 7tm Chemosensory receptor AAA_23 PF13476.1 CDI84626.1 - 0.23 11.7 0.0 0.23 11.7 0.0 2.5 2 1 0 2 2 2 0 AAA domain LMBR1 PF04791.11 CDI84626.1 - 0.37 9.3 4.2 2.5 6.6 2.9 2.3 1 1 0 1 1 1 0 LMBR1-like membrane protein Neur_chan_memb PF02932.11 CDI84626.1 - 6.3 6.6 22.0 1.8 8.3 7.8 2.8 3 1 0 3 3 3 0 Neurotransmitter-gated ion-channel transmembrane region IncA PF04156.9 CDI84628.1 - 8.4e-05 22.2 2.7 8.4e-05 22.2 1.9 2.4 2 1 0 2 2 1 1 IncA protein P22_AR_N PF10547.4 CDI84628.1 - 0.0065 16.2 0.2 0.014 15.2 0.1 1.6 1 0 0 1 1 1 1 P22_AR N-terminal domain DUF4207 PF13904.1 CDI84628.1 - 0.054 12.8 17.3 0.018 14.4 3.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4207) Spt20 PF12090.3 CDI84628.1 - 0.16 11.3 8.2 0.13 11.5 0.3 2.2 2 0 0 2 2 2 0 Spt20 family MSP1_C PF07462.6 CDI84628.1 - 0.21 9.9 4.6 0.31 9.3 3.2 1.3 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Pex14_N PF04695.8 CDI84628.1 - 0.27 11.2 12.2 1.8 8.6 0.9 2.3 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region FimP PF09766.4 CDI84628.1 - 0.37 9.8 15.9 0.17 10.9 4.3 2.2 2 0 0 2 2 2 0 Fms-interacting protein APC_CDC26 PF10471.4 CDI84628.1 - 0.92 10.2 21.8 4.5 8.0 4.5 2.6 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit 1 ATAD4 PF15321.1 CDI84628.1 - 1.2 10.1 8.7 8.3 7.4 1.3 2.3 2 0 0 2 2 2 0 ATPase family AAA domain containing 4 Ndc1_Nup PF09531.5 CDI84628.1 - 1.4 7.2 3.6 1.8 6.8 2.5 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup MAT1 PF06391.8 CDI84628.1 - 1.5 8.3 16.6 0.13 11.7 4.9 2.1 2 0 0 2 2 2 0 CDK-activating kinase assembly factor MAT1 DUF2347 PF09804.4 CDI84628.1 - 2 7.6 4.8 0.62 9.2 0.4 1.8 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2347) Packaging_FI PF14000.1 CDI84628.1 - 2.3 8.4 8.7 1.2 9.3 3.4 2.1 2 0 0 2 2 2 0 DNA packaging protein FI PHD_3 PF13922.1 CDI84628.1 - 2.9 8.2 13.9 7.1 6.9 2.3 2.5 2 0 0 2 2 2 0 PHD domain of transcriptional enhancer, Asx AIF_C PF14721.1 CDI84628.1 - 3.8 7.7 6.0 1.6 9.0 0.5 2.1 2 0 0 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term RR_TM4-6 PF06459.7 CDI84628.1 - 4.8 6.9 12.1 0.35 10.7 2.8 2.0 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Peptidase_S49_N PF08496.5 CDI84628.1 - 4.9 6.9 7.2 3.1 7.5 1.0 2.2 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Ctr PF04145.10 CDI84628.1 - 6.1 6.8 6.8 16 5.5 0.6 2.2 2 0 0 2 2 2 0 Ctr copper transporter family Pex16 PF08610.5 CDI84628.1 - 6.1 5.7 10.0 5.1 5.9 0.6 2.1 2 0 0 2 2 2 0 Peroxisomal membrane protein (Pex16) FNIP_N PF14636.1 CDI84628.1 - 7.8 6.9 12.8 2.2e+02 2.2 8.9 2.1 1 1 0 1 1 1 0 Folliculin-interacting protein N-terminus Activator_LAG-3 PF11498.3 CDI84628.1 - 8 5.0 30.4 2 7.1 7.0 2.2 2 0 0 2 2 2 0 Transcriptional activator LAG-3 Drc1-Sld2 PF11719.3 CDI84629.1 - 0.38 9.7 18.3 0.44 9.5 12.7 1.0 1 0 0 1 1 1 0 DNA replication and checkpoint protein Vfa1 PF08432.5 CDI84629.1 - 1.3 8.9 17.5 1.6 8.7 12.1 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Pox_Ag35 PF03286.9 CDI84629.1 - 1.4 8.4 22.8 1.6 8.2 15.8 1.0 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Spore_coat_CotO PF14153.1 CDI84629.1 - 1.8 7.9 14.3 1.8 7.9 9.9 1.0 1 0 0 1 1 1 0 Spore coat protein CotO Trypan_PARP PF05887.6 CDI84629.1 - 6 6.6 13.5 6.4 6.5 9.4 1.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) NOA36 PF06524.7 CDI84629.1 - 6.6 5.8 15.3 6.5 5.9 10.6 1.0 1 0 0 1 1 1 0 NOA36 protein PIH1 PF08190.7 CDI84629.1 - 7.4 5.9 11.5 8.1 5.7 7.9 1.0 1 0 0 1 1 1 0 pre-RNA processing PIH1/Nop17 G-7-MTase PF12803.2 CDI84629.1 - 9.2 5.3 7.5 10 5.1 5.2 1.0 1 0 0 1 1 1 0 mRNA (guanine-7-)methyltransferase (G-7-MTase) BUD22 PF09073.5 CDI84629.1 - 10 5.0 21.0 10 5.0 14.5 1.0 1 0 0 1 1 1 0 BUD22 GCC2_GCC3 PF07699.8 CDI84630.1 - 0.02 14.4 6.6 0.092 12.3 4.6 2.1 1 0 0 1 1 1 0 GCC2 and GCC3 DUF755 PF05501.6 CDI84630.1 - 0.028 14.4 0.5 0.028 14.4 0.4 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF755) DUF1510 PF07423.6 CDI84631.1 - 0.00071 19.0 9.3 0.00099 18.5 6.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) Zip PF02535.17 CDI84631.1 - 0.0012 17.9 4.9 0.0012 17.9 3.4 1.2 1 0 0 1 1 1 1 ZIP Zinc transporter Ycf1 PF05758.7 CDI84631.1 - 0.0015 16.3 8.6 0.0015 16.3 6.0 1.0 1 0 0 1 1 1 1 Ycf1 FlgH PF02107.11 CDI84631.1 - 0.002 17.7 0.8 0.0026 17.3 0.6 1.1 1 0 0 1 1 1 1 Flagellar L-ring protein AAA_11 PF13086.1 CDI84631.1 - 0.0024 17.4 7.0 0.0025 17.4 4.9 1.1 1 0 0 1 1 1 1 AAA domain Raftlin PF15250.1 CDI84631.1 - 0.0094 14.5 8.8 0.0099 14.4 6.1 1.1 1 0 0 1 1 1 1 Raftlin Kei1 PF08552.6 CDI84631.1 - 0.011 15.4 5.6 0.019 14.6 3.9 1.4 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 RR_TM4-6 PF06459.7 CDI84631.1 - 0.011 15.6 8.9 0.012 15.5 6.2 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 PBP1_TM PF14812.1 CDI84631.1 - 0.012 15.9 5.6 0.023 15.0 3.9 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Hex_IIIa PF02455.11 CDI84631.1 - 0.015 14.0 5.7 0.017 13.8 4.0 1.0 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) FLO_LFY PF01698.11 CDI84631.1 - 0.017 14.0 8.4 0.017 13.9 5.8 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein Med19 PF10278.4 CDI84631.1 - 0.024 14.3 10.3 0.034 13.8 7.2 1.2 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 DUF913 PF06025.7 CDI84631.1 - 0.03 13.0 2.1 0.032 12.9 1.4 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Hid1 PF12722.2 CDI84631.1 - 0.035 11.7 8.2 0.033 11.8 5.7 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein YqfQ PF14181.1 CDI84631.1 - 0.043 13.8 12.1 0.079 13.0 8.4 1.5 1 0 0 1 1 1 0 YqfQ-like protein DHHW PF14286.1 CDI84631.1 - 0.043 13.1 8.0 0.066 12.5 5.5 1.2 1 0 0 1 1 1 0 DHHW protein Spore_coat_CotO PF14153.1 CDI84631.1 - 0.048 13.0 20.3 0.09 12.2 14.1 1.4 1 0 0 1 1 1 0 Spore coat protein CotO RP-C_C PF11800.3 CDI84631.1 - 0.049 13.3 9.8 0.078 12.6 6.8 1.3 1 0 0 1 1 1 0 Replication protein C C-terminal region Vma12 PF11712.3 CDI84631.1 - 0.05 13.3 4.1 0.058 13.0 2.8 1.3 1 0 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Plasmodium_Vir PF05795.6 CDI84631.1 - 0.052 12.7 0.2 0.065 12.4 0.2 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Gti1_Pac2 PF09729.4 CDI84631.1 - 0.062 13.1 6.1 0.098 12.5 4.3 1.3 1 0 0 1 1 1 0 Gti1/Pac2 family DUF2370 PF10176.4 CDI84631.1 - 0.08 12.2 3.0 0.12 11.7 2.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) GAGA_bind PF06217.7 CDI84631.1 - 0.13 12.2 11.6 0.14 12.0 8.1 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family DUF2126 PF09899.4 CDI84631.1 - 0.15 10.0 10.4 0.068 11.1 5.8 1.4 2 0 0 2 2 2 0 Putative amidoligase enzyme (DUF2126) DUF605 PF04652.11 CDI84631.1 - 0.16 11.2 15.0 0.22 10.8 10.4 1.1 1 0 0 1 1 1 0 Vta1 like Borrelia_P83 PF05262.6 CDI84631.1 - 0.23 9.7 12.6 0.22 9.7 8.7 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein AAA_23 PF13476.1 CDI84631.1 - 0.23 11.7 11.2 0.26 11.6 7.8 1.2 1 0 0 1 1 1 0 AAA domain Pex14_N PF04695.8 CDI84631.1 - 0.25 11.4 16.5 0.051 13.6 8.5 1.8 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region SID-1_RNA_chan PF13965.1 CDI84631.1 - 0.27 9.3 5.2 0.35 8.9 3.6 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Peptidase_S49_N PF08496.5 CDI84631.1 - 0.28 10.9 12.1 0.46 10.2 8.4 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Pox_Ag35 PF03286.9 CDI84631.1 - 0.29 10.6 10.6 0.44 10.0 7.4 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DUF4220 PF13968.1 CDI84631.1 - 0.34 9.9 7.8 0.43 9.6 5.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4220) Anoctamin PF04547.7 CDI84631.1 - 0.48 9.0 4.5 0.54 8.8 3.1 1.2 1 0 0 1 1 1 0 Calcium-activated chloride channel DUF940 PF06082.6 CDI84631.1 - 0.58 8.6 5.8 0.66 8.4 4.0 1.1 1 0 0 1 1 1 0 Bacterial putative lipoprotein (DUF940) DDRGK PF09756.4 CDI84631.1 - 0.61 9.4 26.6 0.92 8.8 18.4 1.2 1 0 0 1 1 1 0 DDRGK domain SeqA PF03925.8 CDI84631.1 - 0.72 9.5 10.2 1.3 8.6 7.1 1.4 1 0 0 1 1 1 0 SeqA protein UPF0560 PF10577.4 CDI84631.1 - 0.88 7.7 14.5 0.92 7.6 10.1 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 FAM60A PF15396.1 CDI84631.1 - 1.1 9.0 10.5 1.7 8.3 7.3 1.3 1 0 0 1 1 1 0 Protein Family FAM60A DUF3464 PF11947.3 CDI84631.1 - 1.1 8.7 9.9 1.8 7.9 6.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) DDHD PF02862.12 CDI84631.1 - 1.1 9.0 11.7 1.6 8.4 8.1 1.2 1 0 0 1 1 1 0 DDHD domain DUF4557 PF15101.1 CDI84631.1 - 1.1 9.0 20.0 2.1 8.1 13.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) NARP1 PF12569.3 CDI84631.1 - 1.1 7.9 15.6 1.5 7.4 10.8 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 CHD5 PF04420.9 CDI84631.1 - 1.1 8.8 6.6 1.8 8.1 4.6 1.4 1 0 0 1 1 1 0 CHD5-like protein Peptidase_S15 PF02129.13 CDI84631.1 - 1.1 8.5 7.1 1.5 8.1 4.9 1.2 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) CPSF100_C PF13299.1 CDI84631.1 - 1.2 9.3 9.9 2.1 8.5 6.8 1.4 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Band_3_cyto PF07565.8 CDI84631.1 - 1.3 8.5 16.1 0.9 8.9 10.2 1.4 2 0 0 2 2 1 0 Band 3 cytoplasmic domain CobT PF06213.7 CDI84631.1 - 2.3 7.2 13.6 3.7 6.6 9.5 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT OATP PF03137.15 CDI84631.1 - 2.5 6.0 8.0 3.4 5.6 5.5 1.3 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Paramyxo_ncap PF00973.14 CDI84631.1 - 2.6 6.6 10.7 3.5 6.2 7.4 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Paf1 PF03985.8 CDI84631.1 - 2.8 6.6 21.8 4.1 6.0 15.1 1.2 1 0 0 1 1 1 0 Paf1 Nucleoside_tran PF01733.13 CDI84631.1 - 3.3 6.8 7.1 5.1 6.1 4.9 1.3 1 0 0 1 1 1 0 Nucleoside transporter Cellulose_synt PF03552.9 CDI84631.1 - 3.4 5.8 5.8 4.3 5.5 4.0 1.1 1 0 0 1 1 1 0 Cellulose synthase HGTP_anticodon2 PF12745.2 CDI84631.1 - 3.7 6.6 15.9 5.8 5.9 11.0 1.3 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs HemX PF04375.9 CDI84631.1 - 3.8 5.9 20.7 4.7 5.7 14.4 1.2 1 0 0 1 1 1 0 HemX Membralin PF09746.4 CDI84631.1 - 3.9 6.4 5.4 5.1 6.0 3.7 1.1 1 0 0 1 1 1 0 Tumour-associated protein Asp-B-Hydro_N PF05279.6 CDI84631.1 - 4 7.2 16.3 6.6 6.5 11.3 1.3 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region PAT1 PF09770.4 CDI84631.1 - 4.4 5.4 34.2 6 4.9 23.7 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Pal1 PF08316.6 CDI84631.1 - 4.4 7.7 8.3 7.1 7.0 5.8 1.3 1 0 0 1 1 1 0 Pal1 cell morphology protein Baculo_PP31 PF05311.6 CDI84631.1 - 4.4 6.4 13.2 6.8 5.8 9.1 1.3 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) Endonuc_Holl PF10107.4 CDI84631.1 - 4.5 6.9 14.3 7.2 6.2 9.9 1.3 1 0 0 1 1 1 0 Endonuclease related to archaeal Holliday junction resolvase CDC45 PF02724.9 CDI84631.1 - 5.2 4.9 15.6 6.7 4.6 10.8 1.1 1 0 0 1 1 1 0 CDC45-like protein APG6 PF04111.7 CDI84631.1 - 5.4 5.9 19.3 7.2 5.5 13.4 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Hom_end_hint PF05203.11 CDI84631.1 - 7 6.3 12.8 11 5.6 8.9 1.3 1 0 0 1 1 1 0 Hom_end-associated Hint Med15 PF09606.5 CDI84631.1 - 8.6 4.4 42.0 11 4.0 29.1 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal BORG_CEP PF14957.1 CDI84631.1 - 9.6 7.1 11.1 12 6.8 6.9 1.7 2 0 0 2 2 1 0 Cdc42 effector DUF4407 PF14362.1 CDI84631.1 - 9.8 5.0 17.2 14 4.4 11.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) GCC2_GCC3 PF07699.8 CDI84632.1 - 0.0011 18.4 9.0 0.0011 18.4 6.2 3.9 2 1 2 4 4 4 2 GCC2 and GCC3 Dickkopf_N PF04706.7 CDI84632.1 - 0.34 11.1 4.6 3.3 7.9 0.9 3.0 1 1 2 3 3 3 0 Dickkopf N-terminal cysteine-rich region NCD3G PF07562.9 CDI84632.1 - 1.2 8.9 13.4 0.049 13.3 2.0 3.4 3 2 1 4 4 4 0 Nine Cysteines Domain of family 3 GPCR TNFR_c6 PF00020.13 CDI84632.1 - 2.1 8.4 13.1 0.42 10.7 0.2 4.0 2 2 1 3 3 3 0 TNFR/NGFR cysteine-rich region YoaP PF14268.1 CDI84632.1 - 4.9 6.4 7.4 3.7 6.8 0.2 3.4 4 0 0 4 4 4 0 YoaP-like GCC2_GCC3 PF07699.8 CDI84633.1 - 3.6e-12 45.6 387.7 0.00012 21.6 4.5 35.2 23 12 8 32 32 32 22 GCC2 and GCC3 PAN_4 PF14295.1 CDI84634.1 - 9.5e-07 28.4 0.1 1.9e-06 27.4 0.1 1.5 1 0 0 1 1 1 1 PAN domain PAN_1 PF00024.21 CDI84634.1 - 1.7e-05 24.4 0.0 4.8e-05 23.0 0.0 1.7 1 0 0 1 1 1 1 PAN domain PAN_2 PF08276.6 CDI84634.1 - 0.0016 18.2 0.0 0.0037 17.0 0.0 1.6 1 0 0 1 1 1 1 PAN-like domain cNMP_binding PF00027.24 CDI84635.1 - 7e-11 41.7 0.0 1.6e-06 27.8 0.0 3.6 3 1 0 3 3 3 2 Cyclic nucleotide-binding domain SelP_N PF04592.9 CDI84637.1 - 0.025 13.9 26.3 0.03 13.6 18.2 1.0 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Peptidase_S49_N PF08496.5 CDI84637.1 - 0.2 11.4 15.3 0.24 11.1 10.6 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal CDC45 PF02724.9 CDI84637.1 - 0.23 9.4 16.9 0.24 9.3 11.7 1.0 1 0 0 1 1 1 0 CDC45-like protein BTV_NS2 PF04514.7 CDI84637.1 - 0.4 9.5 15.3 0.43 9.4 10.6 1.0 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Pox_Ag35 PF03286.9 CDI84637.1 - 0.54 9.7 11.8 0.55 9.7 8.2 1.0 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Ribosomal_60s PF00428.14 CDI84637.1 - 0.62 10.4 4.6 0.89 9.9 3.2 1.3 1 0 0 1 1 1 0 60s Acidic ribosomal protein DUF1510 PF07423.6 CDI84637.1 - 1 8.6 19.9 1.2 8.4 13.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) GBP_C PF02841.9 CDI84637.1 - 1.2 8.2 28.0 1.4 8.0 19.4 1.1 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain NicO PF03824.11 CDI84637.1 - 1.2 8.3 8.6 1.4 8.1 6.0 1.3 1 0 0 1 1 1 0 High-affinity nickel-transport protein Zip PF02535.17 CDI84637.1 - 1.3 7.9 19.9 1.5 7.7 13.8 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Peptidase_U57 PF05582.7 CDI84637.1 - 1.7 7.5 13.4 1.9 7.3 9.3 1.1 1 0 0 1 1 1 0 YabG peptidase U57 DDRGK PF09756.4 CDI84637.1 - 1.9 7.8 24.8 2.2 7.6 17.2 1.1 1 0 0 1 1 1 0 DDRGK domain Serinc PF03348.10 CDI84637.1 - 1.9 7.0 16.5 2.5 6.7 11.4 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) FLO_LFY PF01698.11 CDI84637.1 - 2 7.2 18.7 2.1 7.1 13.0 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein DUF3984 PF13136.1 CDI84637.1 - 2.1 7.5 20.1 2.3 7.3 13.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3984) DUF4446 PF14584.1 CDI84637.1 - 2.2 8.0 10.0 2.8 7.7 7.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) FAM60A PF15396.1 CDI84637.1 - 2.5 7.7 17.0 3 7.5 11.8 1.1 1 0 0 1 1 1 0 Protein Family FAM60A PAT1 PF09770.4 CDI84637.1 - 2.6 6.1 46.3 3 5.9 32.1 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF3824 PF12868.2 CDI84637.1 - 2.7 8.9 17.9 10 7.0 12.4 1.6 1 1 0 1 1 1 0 Domain of unknwon function (DUF3824) Pal1 PF08316.6 CDI84637.1 - 2.8 8.3 13.1 3.4 8.1 9.1 1.1 1 0 0 1 1 1 0 Pal1 cell morphology protein UPF0564 PF10595.4 CDI84637.1 - 2.9 6.6 31.1 3.2 6.5 21.6 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0564 Pneumo_phosprot PF02478.11 CDI84637.1 - 3 7.3 8.5 3.5 7.0 5.9 1.0 1 0 0 1 1 1 0 Pneumovirus phosphoprotein DUF4045 PF13254.1 CDI84637.1 - 3.2 6.9 17.8 3.3 6.8 12.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Folate_carrier PF01770.13 CDI84637.1 - 3.5 6.0 10.4 3.8 5.9 7.2 1.1 1 0 0 1 1 1 0 Reduced folate carrier DUF2215 PF10225.4 CDI84637.1 - 3.5 6.9 8.9 4.2 6.7 6.2 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) Spc7_N PF15402.1 CDI84637.1 - 3.6 5.4 23.9 4.2 5.2 16.6 1.0 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 Presenilin PF01080.12 CDI84637.1 - 3.6 6.2 15.4 4.3 6.0 10.7 1.0 1 0 0 1 1 1 0 Presenilin Rtf2 PF04641.7 CDI84637.1 - 3.7 6.6 19.7 4.1 6.5 13.7 1.0 1 0 0 1 1 1 0 Rtf2 RING-finger Helicase_RecD PF05127.9 CDI84637.1 - 4.7 6.8 11.1 5.7 6.5 7.7 1.3 1 0 0 1 1 1 0 Helicase Raftlin PF15250.1 CDI84637.1 - 5.5 5.4 19.8 5.8 5.3 13.7 1.0 1 0 0 1 1 1 0 Raftlin RIC3 PF15361.1 CDI84637.1 - 6.2 7.0 21.1 8.6 6.5 14.6 1.3 1 0 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 Cyclin_C PF02984.14 CDI84637.1 - 6.2 6.7 14.5 8.3 6.3 10.1 1.2 1 0 0 1 1 1 0 Cyclin, C-terminal domain RR_TM4-6 PF06459.7 CDI84637.1 - 6.3 6.6 19.2 7.1 6.4 13.3 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 TCP PF03634.8 CDI84637.1 - 6.4 7.1 25.2 8.3 6.7 17.5 1.1 1 0 0 1 1 1 0 TCP family transcription factor Dynamin_N PF00350.18 CDI84637.1 - 6.4 6.5 10.5 9.4 6.0 7.2 1.3 1 0 0 1 1 1 0 Dynamin family Cellulose_synt PF03552.9 CDI84637.1 - 6.9 4.8 9.1 6.7 4.8 6.3 1.0 1 0 0 1 1 1 0 Cellulose synthase YjgP_YjgQ PF03739.9 CDI84637.1 - 7.2 5.2 6.6 8.2 5.0 4.6 1.1 1 0 0 1 1 1 0 Predicted permease YjgP/YjgQ family PPP4R2 PF09184.6 CDI84637.1 - 7.3 6.0 15.7 8.4 5.8 10.9 1.1 1 0 0 1 1 1 0 PPP4R2 Lipoprotein_X PF03305.8 CDI84637.1 - 7.3 5.8 15.9 8.1 5.7 11.0 1.0 1 0 0 1 1 1 0 Mycoplasma MG185/MG260 protein DDHD PF02862.12 CDI84637.1 - 7.3 6.3 18.8 8.7 6.0 13.0 1.0 1 0 0 1 1 1 0 DDHD domain Med15 PF09606.5 CDI84637.1 - 7.6 4.5 59.5 8.5 4.4 41.2 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal AUX_IAA PF02309.11 CDI84637.1 - 7.9 6.1 16.2 9.3 5.9 11.2 1.1 1 0 0 1 1 1 0 AUX/IAA family Gti1_Pac2 PF09729.4 CDI84637.1 - 7.9 6.3 14.4 10 5.9 10.0 1.3 1 0 0 1 1 1 0 Gti1/Pac2 family Med19 PF10278.4 CDI84637.1 - 8.3 6.0 15.5 13 5.4 10.7 1.3 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 FliP PF00813.15 CDI84637.1 - 8.4 6.0 11.4 9.5 5.8 7.9 1.0 1 0 0 1 1 1 0 FliP family CDK5_activator PF03261.10 CDI84637.1 - 8.6 5.5 20.0 9.2 5.4 13.8 1.0 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein CKAP2_C PF15297.1 CDI84637.1 - 8.6 5.0 19.7 9.8 4.8 13.6 1.1 1 0 0 1 1 1 0 Cytoskeleton-associated protein 2 C-terminus Tim54 PF11711.3 CDI84637.1 - 8.6 4.8 15.4 10 4.6 10.7 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Acyl-thio_N PF12590.3 CDI84637.1 - 8.7 6.8 9.5 11 6.5 6.6 1.1 1 0 0 1 1 1 0 Acyl-ATP thioesterase eIF-3_zeta PF05091.7 CDI84637.1 - 8.9 4.7 23.9 8.6 4.8 16.6 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF4175 PF13779.1 CDI84637.1 - 9.7 3.7 48.7 11 3.5 33.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Ycf1 PF05758.7 CDI84638.1 - 7.8e-07 27.2 20.2 9.2e-07 27.0 14.0 1.1 1 0 0 1 1 1 1 Ycf1 SpoIIIAH PF12685.2 CDI84638.1 - 0.0006 19.3 19.0 0.0015 18.0 13.2 1.7 1 1 0 1 1 1 1 SpoIIIAH-like protein Neur_chan_memb PF02932.11 CDI84638.1 - 0.0016 18.3 12.5 0.0026 17.6 8.7 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Herpes_UL87 PF03043.9 CDI84638.1 - 0.01 14.2 11.4 0.011 14.1 7.9 1.1 1 0 0 1 1 1 0 Herpesvirus UL87 family SPX PF03105.14 CDI84638.1 - 0.031 14.0 18.4 0.038 13.7 12.7 1.4 1 0 0 1 1 1 0 SPX domain DUF1510 PF07423.6 CDI84638.1 - 0.56 9.5 40.6 2.1 7.6 28.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1510) DUF3332 PF11810.3 CDI84638.1 - 0.6 9.7 9.0 0.89 9.1 6.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3332) Zip PF02535.17 CDI84638.1 - 0.73 8.7 18.9 2.1 7.3 13.1 1.7 1 1 0 1 1 1 0 ZIP Zinc transporter Silic_transp PF03842.8 CDI84638.1 - 1.3 7.0 5.1 1.7 6.5 3.5 1.2 1 0 0 1 1 1 0 Silicon transporter PA26 PF04636.8 CDI84638.1 - 1.4 7.5 18.9 1.7 7.2 13.1 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Membralin PF09746.4 CDI84638.1 - 1.8 7.5 14.0 2.8 6.8 9.7 1.3 1 0 0 1 1 1 0 Tumour-associated protein DUF4045 PF13254.1 CDI84638.1 - 5.3 6.2 28.6 7.5 5.7 19.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) DUF2146 PF10220.4 CDI84638.1 - 9 4.1 26.8 12 3.7 18.5 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2146) CAF-1_p150 PF11600.3 CDI84639.1 - 5.2 6.3 25.2 7.5 5.8 17.5 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF2029 PF09594.5 CDI84641.1 - 0.017 14.6 7.2 0.025 14.0 5.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2029) DUF3807 PF12720.2 CDI84643.1 - 8.5 6.4 18.2 13 5.8 12.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) Tim54 PF11711.3 CDI84643.1 - 8.8 4.8 7.8 11 4.4 5.4 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Hid1 PF12722.2 CDI84643.1 - 9.6 3.7 36.9 11 3.5 25.6 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein MFS_Mycoplasma PF07672.8 CDI84644.1 - 0.02 14.0 0.5 0.02 14.0 0.3 2.0 1 1 1 2 2 1 0 Mycoplasma MFS transporter Pex16 PF08610.5 CDI84644.1 - 0.057 12.4 8.4 0.087 11.8 5.8 1.2 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) FimP PF09766.4 CDI84644.1 - 0.062 12.3 18.9 0.027 13.5 7.4 2.1 2 0 0 2 2 2 0 Fms-interacting protein DDHD PF02862.12 CDI84644.1 - 0.13 12.0 5.9 0.18 11.5 4.1 1.3 1 0 0 1 1 1 0 DDHD domain BRF1 PF07741.8 CDI84644.1 - 0.23 11.6 17.1 0.47 10.6 7.7 2.4 1 1 1 2 2 2 0 Brf1-like TBP-binding domain PAT1 PF09770.4 CDI84644.1 - 0.35 9.0 28.8 0.42 8.7 20.0 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 LMBR1 PF04791.11 CDI84644.1 - 0.47 8.9 10.3 1.1 7.7 7.2 1.6 1 1 0 1 1 1 0 LMBR1-like membrane protein MRP-S31 PF15433.1 CDI84644.1 - 0.6 9.4 14.8 0.87 8.9 10.3 1.3 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 dsDNA_bind PF01984.15 CDI84644.1 - 0.63 10.0 33.3 0.76 9.7 12.2 2.4 2 0 0 2 2 2 0 Double-stranded DNA-binding domain Gag_p17 PF00540.13 CDI84644.1 - 0.85 9.3 8.0 0.72 9.6 1.8 2.5 2 0 0 2 2 2 0 gag gene protein p17 (matrix protein) DUF775 PF05603.7 CDI84644.1 - 0.91 8.9 14.5 2.2 7.7 5.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF775) Peptidase_C12 PF01088.16 CDI84644.1 - 1.5 7.9 12.8 0.19 10.8 0.5 2.2 1 1 1 2 2 2 0 Ubiquitin carboxyl-terminal hydrolase, family 1 UPF0233 PF06781.7 CDI84644.1 - 2.6 7.7 8.2 3.5 7.3 0.1 2.7 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0233) TFIIA PF03153.8 CDI84644.1 - 2.7 7.8 24.0 4 7.2 16.6 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit TAS2R PF05296.8 CDI84644.1 - 3.4 6.4 9.6 0.67 8.7 4.1 1.7 1 1 0 1 1 1 0 Mammalian taste receptor protein (TAS2R) Virul_fac_BrkB PF03631.10 CDI84644.1 - 3.6 6.8 23.5 6.7 5.9 16.3 1.5 1 1 0 1 1 1 0 Virulence factor BrkB Baculo_ODV-E27 PF05314.6 CDI84644.1 - 3.7 6.5 8.9 1.1 8.2 1.1 2.1 1 1 1 2 2 2 0 Baculovirus occlusion-derived virus envelope protein EC27 Fig1 PF12351.3 CDI84644.1 - 3.8 7.3 11.3 5.3 6.8 7.8 1.4 1 1 0 1 1 1 0 Ca2+ regulator and membrane fusion protein Fig1 MRP-S26 PF14943.1 CDI84644.1 - 5 6.6 22.1 0.22 11.0 9.1 2.1 2 0 0 2 2 2 0 Mitochondrial ribosome subunit S26 PHD_3 PF13922.1 CDI84644.1 - 5.4 7.3 21.9 3.3 8.0 6.8 2.6 2 0 0 2 2 2 0 PHD domain of transcriptional enhancer, Asx DUF4131 PF13567.1 CDI84645.1 - 0.033 13.6 0.9 0.087 12.2 0.6 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) FA_desaturase PF00487.19 CDI84645.1 - 0.17 11.2 0.5 0.26 10.6 0.3 1.3 1 0 0 1 1 1 0 Fatty acid desaturase TFIIA PF03153.8 CDI84645.1 - 9.2 6.0 16.0 13 5.5 11.1 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Cyto_ox_2 PF02322.10 CDI84646.1 - 0.35 10.0 9.0 0.58 9.2 6.2 1.3 1 0 0 1 1 1 0 Cytochrome oxidase subunit II AAA_23 PF13476.1 CDI84646.1 - 5.3 7.3 42.6 5.3 7.3 13.0 2.1 2 0 0 2 2 2 0 AAA domain ARGLU PF15346.1 CDI84646.1 - 5.9 6.6 42.5 1.4 8.7 7.6 2.5 3 0 0 3 3 3 0 Arginine and glutamate-rich 1 Daxx PF03344.10 CDI84647.1 - 0.19 10.2 51.3 0.24 9.8 35.6 1.2 1 0 0 1 1 1 0 Daxx Family Asp-B-Hydro_N PF05279.6 CDI84647.1 - 0.53 10.1 48.1 0.9 9.3 33.3 1.4 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region BAF1_ABF1 PF04684.8 CDI84649.1 - 0.0062 15.4 27.5 0.0062 15.4 19.0 5.2 1 1 3 5 5 5 2 BAF1 / ABF1 chromatin reorganising factor Activator_LAG-3 PF11498.3 CDI84650.1 - 0.69 8.6 14.2 0.9 8.2 9.9 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Med15 PF09606.5 CDI84650.1 - 2.9 5.9 22.8 3.4 5.7 15.8 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal PHD_3 PF13922.1 CDI84650.1 - 3.5 7.9 5.9 6.8 7.0 4.1 1.4 1 0 0 1 1 1 0 PHD domain of transcriptional enhancer, Asx DUF2457 PF10446.4 CDI84651.1 - 4.6 5.8 35.9 5.4 5.6 24.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Daxx PF03344.10 CDI84651.1 - 5.5 5.3 11.1 6.4 5.1 7.7 1.2 1 0 0 1 1 1 0 Daxx Family Astro_capsid PF03115.9 CDI84651.1 - 5.7 5.0 9.3 5.9 5.0 6.5 1.1 1 0 0 1 1 1 0 Astrovirus capsid protein precursor Sororin PF09666.5 CDI84653.1 - 0.43 10.7 11.3 0.7 10.0 7.8 1.4 1 1 0 1 1 1 0 Sororin protein Activator_LAG-3 PF11498.3 CDI84653.1 - 0.87 8.2 55.2 1.1 7.9 38.2 1.0 1 0 0 1 1 1 0 Transcriptional activator LAG-3 OATP PF03137.15 CDI84653.1 - 7.7 4.4 6.4 11 3.9 4.4 1.2 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family SprA-related PF12118.3 CDI84654.1 - 0.0011 18.3 12.4 0.0011 18.3 8.6 4.4 3 2 0 3 3 3 1 SprA-related family Apt1 PF10351.4 CDI84654.1 - 1.6 7.5 0.0 1.6 7.5 0.0 3.2 3 1 0 3 3 3 0 Golgi-body localisation protein domain Presenilin PF01080.12 CDI84655.1 - 0.0081 15.0 10.9 0.0087 14.9 7.6 1.0 1 0 0 1 1 1 1 Presenilin DUF3138 PF11336.3 CDI84655.1 - 0.051 11.7 1.4 0.057 11.5 1.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Band_3_cyto PF07565.8 CDI84655.1 - 0.15 11.5 4.1 0.18 11.3 2.8 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain SBF2 PF12335.3 CDI84655.1 - 0.16 11.2 5.2 0.17 11.1 3.6 1.2 1 0 0 1 1 1 0 Myotubularin protein KAP PF05804.7 CDI84655.1 - 0.34 8.7 1.6 0.39 8.5 1.1 1.0 1 0 0 1 1 1 0 Kinesin-associated protein (KAP) FAM60A PF15396.1 CDI84655.1 - 0.63 9.7 8.8 0.72 9.5 6.1 1.2 1 0 0 1 1 1 0 Protein Family FAM60A RAP1 PF07218.6 CDI84655.1 - 0.75 7.8 8.7 0.81 7.7 6.0 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) F-protein PF00469.15 CDI84655.1 - 1.2 8.5 7.7 1.2 8.4 5.4 1.2 1 0 0 1 1 1 0 Negative factor, (F-Protein) or Nef Metal_resist PF13801.1 CDI84655.1 - 1.4 8.8 5.6 3.7 7.5 3.9 1.8 1 1 0 1 1 1 0 Heavy-metal resistance DUF755 PF05501.6 CDI84655.1 - 1.7 8.7 19.3 0.1 12.6 9.9 1.6 2 0 0 2 2 1 0 Domain of unknown function (DUF755) Membralin PF09746.4 CDI84655.1 - 2.3 7.1 5.3 2.5 7.0 3.7 1.0 1 0 0 1 1 1 0 Tumour-associated protein Chorion_2 PF03964.10 CDI84655.1 - 2.7 8.6 10.6 3.1 8.4 7.3 1.3 1 1 0 1 1 1 0 Chorion family 2 SAPS PF04499.10 CDI84655.1 - 3.3 6.2 11.6 4 5.9 8.1 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF2217 PF10265.4 CDI84655.1 - 3.6 6.2 9.3 4.3 5.9 6.5 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) FancD2 PF14631.1 CDI84655.1 - 3.7 4.5 8.5 4.2 4.3 5.9 1.0 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease AUX_IAA PF02309.11 CDI84655.1 - 4.3 7.0 9.8 5.1 6.7 6.8 1.1 1 0 0 1 1 1 0 AUX/IAA family Bul1_C PF04426.7 CDI84655.1 - 4.7 6.3 8.7 6.4 5.8 6.0 1.1 1 0 0 1 1 1 0 Bul1 C terminus Orthopox_A36R PF05950.6 CDI84655.1 - 5.1 7.0 6.2 7.6 6.4 4.3 1.2 1 0 0 1 1 1 0 Orthopoxvirus A36R protein DUF4551 PF15087.1 CDI84655.1 - 6 5.1 8.7 6.1 5.0 6.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) KBP_C PF12309.3 CDI84656.1 - 1.3e-13 50.7 0.0 1.3e-13 50.7 0.0 6.9 4 2 1 5 5 5 1 KIF-1 binding protein C terminal SR-25 PF10500.4 CDI84656.1 - 4.4e-06 26.3 33.4 5.9e-05 22.6 11.9 8.4 7 2 1 8 8 8 2 Nuclear RNA-splicing-associated protein Suf PF05843.9 CDI84656.1 - 0.00034 20.4 11.0 0.00034 20.4 7.6 7.4 3 1 1 5 5 5 2 Suppressor of forked protein (Suf) Spt20 PF12090.3 CDI84656.1 - 0.0015 17.8 1.3 0.0015 17.8 0.9 8.4 3 1 2 6 6 6 2 Spt20 family Med15 PF09606.5 CDI84657.1 - 0.0017 16.6 65.1 0.0017 16.6 45.1 3.0 1 1 2 3 3 3 2 ARC105 or Med15 subunit of Mediator complex non-fungal Phostensin_N PF13916.1 CDI84657.1 - 0.0036 17.2 2.0 0.0036 17.2 1.4 5.8 4 2 0 4 4 4 1 PP1-regulatory protein, Phostensin N-terminal CAF-1_p150 PF11600.3 CDI84657.1 - 2.6 7.3 47.4 4 6.7 0.7 3.2 3 0 0 3 3 3 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF2217 PF10265.4 CDI84658.1 - 0.56 8.9 35.5 67 2.0 24.6 2.0 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) DUF4207 PF13904.1 CDI84658.1 - 2.9 7.2 61.9 0.26 10.6 29.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4207) CDC45 PF02724.9 CDI84659.1 - 0.89 7.5 18.9 1.1 7.2 13.1 1.2 1 0 0 1 1 1 0 CDC45-like protein Macoilin PF09726.4 CDI84659.1 - 0.99 7.6 20.7 1.3 7.2 14.3 1.2 1 0 0 1 1 1 0 Transmembrane protein PLRV_ORF5 PF01690.12 CDI84659.1 - 2.2 7.3 28.3 3.1 6.8 19.6 1.3 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Ycf1 PF05758.7 CDI84659.1 - 4.2 4.9 19.6 4.4 4.8 13.6 1.1 1 0 0 1 1 1 0 Ycf1 Plasmodium_Vir PF05795.6 CDI84659.1 - 4.5 6.3 7.2 6.4 5.8 5.0 1.3 1 0 0 1 1 1 0 Plasmodium vivax Vir protein DUF966 PF06136.8 CDI84659.1 - 7.3 5.9 27.2 9.1 5.5 18.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF966) LMBR1 PF04791.11 CDI84659.1 - 7.6 4.9 6.8 12 4.3 4.7 1.2 1 1 0 1 1 1 0 LMBR1-like membrane protein FHIPEP PF00771.15 CDI84660.1 - 0.0028 16.0 4.9 0.0031 15.9 3.4 1.1 1 0 0 1 1 1 1 FHIPEP family FAM176 PF14851.1 CDI84660.1 - 0.0059 16.2 0.7 0.0072 16.0 0.5 1.2 1 0 0 1 1 1 1 FAM176 family Ycf1 PF05758.7 CDI84660.1 - 0.012 13.3 8.5 0.011 13.4 5.9 1.0 1 0 0 1 1 1 0 Ycf1 Baculo_PP31 PF05311.6 CDI84660.1 - 0.013 14.7 9.4 0.011 14.9 6.5 1.0 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) Serinc PF03348.10 CDI84660.1 - 0.039 12.6 9.6 0.042 12.5 6.6 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) CPSF100_C PF13299.1 CDI84660.1 - 0.054 13.6 7.5 0.051 13.7 5.2 1.1 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Hid1 PF12722.2 CDI84660.1 - 0.08 10.6 14.0 0.085 10.5 9.7 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DDHD PF02862.12 CDI84660.1 - 0.081 12.7 11.0 0.083 12.6 7.6 1.1 1 0 0 1 1 1 0 DDHD domain Prog_receptor PF02161.10 CDI84660.1 - 0.091 11.5 9.3 0.092 11.5 6.4 1.0 1 0 0 1 1 1 0 Progesterone receptor DUF2072 PF09845.4 CDI84660.1 - 0.095 12.6 9.0 0.12 12.3 6.2 1.1 1 0 0 1 1 1 0 Zn-ribbon containing protein (DUF2072) Peroxin-13_N PF04088.8 CDI84660.1 - 0.096 12.6 3.8 0.1 12.5 2.7 1.3 1 0 0 1 1 1 0 Peroxin 13, N-terminal region OATP PF03137.15 CDI84660.1 - 0.11 10.5 7.3 0.11 10.5 5.1 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Zip PF02535.17 CDI84660.1 - 0.14 11.1 0.2 0.15 11.0 0.2 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter YABBY PF04690.8 CDI84660.1 - 0.18 12.0 5.5 0.17 12.1 3.8 1.1 1 0 0 1 1 1 0 YABBY protein DUF3292 PF11696.3 CDI84660.1 - 0.21 9.4 3.9 0.23 9.3 2.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) Cellulose_synt PF03552.9 CDI84660.1 - 0.28 9.4 2.8 0.26 9.5 2.0 1.0 1 0 0 1 1 1 0 Cellulose synthase FYDLN_acid PF09538.5 CDI84660.1 - 0.28 11.7 5.2 0.32 11.5 3.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) EIIBC-GUT_N PF03612.9 CDI84660.1 - 0.29 10.7 8.2 0.29 10.7 5.7 1.2 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus DcuC PF03606.10 CDI84660.1 - 0.3 9.2 2.6 0.33 9.1 1.8 1.1 1 0 0 1 1 1 0 C4-dicarboxylate anaerobic carrier DUF853 PF05872.7 CDI84660.1 - 0.34 9.2 9.8 0.3 9.3 6.8 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) Vps39_2 PF10367.4 CDI84660.1 - 0.35 11.0 9.6 0.45 10.6 6.7 1.2 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 2 Nucleoside_tran PF01733.13 CDI84660.1 - 0.37 9.9 3.9 0.43 9.6 2.7 1.1 1 0 0 1 1 1 0 Nucleoside transporter YfhO PF09586.5 CDI84660.1 - 0.37 8.7 8.8 0.37 8.7 6.1 1.0 1 0 0 1 1 1 0 Bacterial membrane protein YfhO Dala_Dala_lig_N PF01820.16 CDI84660.1 - 0.42 10.9 5.4 0.47 10.7 3.8 1.2 1 0 0 1 1 1 0 D-ala D-ala ligase N-terminus FLO_LFY PF01698.11 CDI84660.1 - 0.44 9.3 11.4 0.45 9.3 7.9 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein SID-1_RNA_chan PF13965.1 CDI84660.1 - 0.47 8.5 4.8 0.46 8.5 3.3 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DUF3260 PF11658.3 CDI84660.1 - 0.48 8.5 11.4 0.47 8.5 7.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3260) AUX_IAA PF02309.11 CDI84660.1 - 0.51 10.0 10.9 0.51 10.0 7.5 1.1 1 0 0 1 1 1 0 AUX/IAA family DUF1980 PF09323.5 CDI84660.1 - 0.58 9.8 8.8 0.53 9.9 6.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) Presenilin PF01080.12 CDI84660.1 - 0.86 8.3 4.5 0.78 8.4 3.1 1.2 1 0 0 1 1 1 0 Presenilin PAT1 PF09770.4 CDI84660.1 - 0.86 7.7 37.9 0.82 7.8 26.2 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 LpxB PF02684.10 CDI84660.1 - 0.89 8.1 7.6 0.82 8.2 5.3 1.1 1 0 0 1 1 1 0 Lipid-A-disaccharide synthetase Mem_trans PF03547.13 CDI84660.1 - 1.1 7.5 5.0 1.4 7.1 3.4 1.1 1 0 0 1 1 1 0 Membrane transport protein Peptidase_S15 PF02129.13 CDI84660.1 - 1.1 8.5 10.3 1 8.7 7.1 1.1 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) CRF1 PF10380.4 CDI84660.1 - 1.2 9.4 8.8 1.3 9.3 6.1 1.1 1 0 0 1 1 1 0 Transcription factor CRF1 Pal1 PF08316.6 CDI84660.1 - 1.4 9.4 5.9 1.5 9.3 4.1 1.1 1 0 0 1 1 1 0 Pal1 cell morphology protein AAA_23 PF13476.1 CDI84660.1 - 2.1 8.6 21.1 2.4 8.4 14.6 1.1 1 0 0 1 1 1 0 AAA domain Med13_N PF11597.3 CDI84660.1 - 2.8 6.5 14.9 2.6 6.6 10.3 1.0 1 0 0 1 1 1 0 Mediator complex subunit 13 N-terminal Cyclin_C PF02984.14 CDI84660.1 - 3.1 7.7 7.9 3.8 7.4 5.5 1.2 1 0 0 1 1 1 0 Cyclin, C-terminal domain DUF2215 PF10225.4 CDI84660.1 - 3.3 7.1 6.9 3.4 7.0 4.8 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) DUF2126 PF09899.4 CDI84660.1 - 3.6 5.4 10.3 3.4 5.5 7.1 1.0 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) RR_TM4-6 PF06459.7 CDI84660.1 - 3.7 7.3 15.1 4 7.2 10.5 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 HD-ZIP_N PF04618.7 CDI84660.1 - 3.9 8.0 7.0 4.3 7.9 4.9 1.2 1 0 0 1 1 1 0 HD-ZIP protein N terminus Band_3_cyto PF07565.8 CDI84660.1 - 4.2 6.8 16.3 4.5 6.7 11.3 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Folate_carrier PF01770.13 CDI84660.1 - 6.4 5.1 14.1 7.3 4.9 9.8 1.2 1 1 0 1 1 1 0 Reduced folate carrier KfrA_N PF11740.3 CDI84660.1 - 8.4 6.8 28.2 10 6.5 19.6 1.2 1 0 0 1 1 1 0 Plasmid replication region DNA-binding N-term NARP1 PF12569.3 CDI84660.1 - 9.7 4.8 17.9 11 4.6 12.4 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 SR-25 PF10500.4 CDI84661.1 - 4.5e-06 26.2 16.7 4.5e-06 26.2 11.6 2.9 2 1 1 3 3 3 1 Nuclear RNA-splicing-associated protein Med15 PF09606.5 CDI84662.1 - 0.0034 15.6 36.4 0.004 15.4 25.3 1.1 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal Exonuc_VII_L PF02601.10 CDI84662.1 - 0.021 14.0 16.5 0.028 13.6 11.4 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Afi1 PF07792.7 CDI84662.1 - 0.029 14.3 8.6 0.046 13.7 6.0 1.3 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking NAD_binding_5 PF07994.7 CDI84662.1 - 0.041 13.3 3.3 0.047 13.1 2.3 1.2 1 0 0 1 1 1 0 Myo-inositol-1-phosphate synthase RGS-like PF09128.6 CDI84662.1 - 0.042 13.3 7.5 0.049 13.1 5.2 1.1 1 0 0 1 1 1 0 Regulator of G protein signalling-like domain Cwf_Cwc_15 PF04889.7 CDI84662.1 - 0.11 12.1 13.1 0.15 11.7 9.1 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF572 PF04502.8 CDI84662.1 - 0.3 10.2 15.6 0.36 10.0 10.8 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) ChaC PF04752.7 CDI84662.1 - 1.3 8.9 6.6 1.8 8.5 4.6 1.2 1 0 0 1 1 1 0 ChaC-like protein PAT1 PF09770.4 CDI84662.1 - 1.6 6.9 32.6 1.8 6.7 22.6 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF966 PF06136.8 CDI84662.1 - 1.6 8.0 21.0 1.8 7.9 14.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Macoilin PF09726.4 CDI84662.1 - 1.7 6.8 21.4 2.1 6.5 14.8 1.1 1 0 0 1 1 1 0 Transmembrane protein DUF2877 PF11392.3 CDI84662.1 - 1.8 8.7 8.3 3.5 7.8 5.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2877) Bac_GDH PF05088.7 CDI84662.1 - 2 5.7 14.8 2.2 5.5 10.2 1.0 1 0 0 1 1 1 0 Bacterial NAD-glutamate dehydrogenase FliP PF00813.15 CDI84662.1 - 2.2 7.9 6.4 2.7 7.6 4.4 1.3 1 0 0 1 1 1 0 FliP family DUF342 PF03961.8 CDI84662.1 - 2.6 6.3 9.0 3 6.1 6.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Conotoxin PF02950.12 CDI84662.1 - 2.9 8.7 11.5 13 6.6 0.3 2.5 2 0 0 2 2 2 0 Conotoxin DDRGK PF09756.4 CDI84662.1 - 3 7.2 19.5 4 6.8 13.5 1.1 1 0 0 1 1 1 0 DDRGK domain Plasmodium_Vir PF05795.6 CDI84662.1 - 3.2 6.8 6.4 4.1 6.4 4.4 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein SOBP PF15279.1 CDI84662.1 - 3.3 8.0 16.8 4.9 7.4 11.7 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein Myco_19_kDa PF05481.7 CDI84662.1 - 3.4 7.4 12.9 10 5.8 0.1 2.2 2 0 0 2 2 2 0 Mycobacterium 19 kDa lipoprotein antigen HAUS6_N PF14661.1 CDI84662.1 - 3.9 6.7 19.0 4.9 6.4 13.2 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Hom_end_hint PF05203.11 CDI84662.1 - 4.1 7.0 8.8 5.8 6.5 6.1 1.3 1 0 0 1 1 1 0 Hom_end-associated Hint MAT1 PF06391.8 CDI84662.1 - 4.8 6.7 19.5 6.2 6.3 13.5 1.1 1 0 0 1 1 1 0 CDK-activating kinase assembly factor MAT1 Ycf1 PF05758.7 CDI84662.1 - 5 4.7 12.3 5.5 4.5 8.5 1.0 1 0 0 1 1 1 0 Ycf1 DUF3573 PF12097.3 CDI84662.1 - 5.4 5.5 11.0 5.7 5.4 7.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) Neur_chan_memb PF02932.11 CDI84662.1 - 5.6 6.7 11.3 7.6 6.3 7.8 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Na_trans_assoc PF06512.8 CDI84662.1 - 8.9 6.2 13.1 13 5.6 9.1 1.2 1 0 0 1 1 1 0 Sodium ion transport-associated APG6 PF04111.7 CDI84662.1 - 10 5.0 20.4 13 4.6 14.1 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Kinase-like PF14531.1 CDI84663.1 - 2e-05 23.7 0.0 5.8e-05 22.2 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Pkinase PF00069.20 CDI84663.1 - 0.00066 18.9 0.0 0.001 18.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain HTH_Tnp_Mu_2 PF09039.6 CDI84663.1 - 0.11 12.2 0.2 5.3 6.8 0.0 2.6 3 0 0 3 3 3 0 Mu DNA binding, I gamma subdomain Ycf1 PF05758.7 CDI84664.1 - 0.0027 15.5 0.7 0.0027 15.5 0.5 2.1 2 0 0 2 2 2 2 Ycf1 Activator_LAG-3 PF11498.3 CDI84664.1 - 0.0033 16.2 17.6 0.0033 16.2 12.2 2.7 2 1 0 2 2 1 1 Transcriptional activator LAG-3 Suf PF05843.9 CDI84664.1 - 0.028 14.1 31.8 0.028 14.1 7.7 2.4 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) Zip PF02535.17 CDI84664.1 - 0.042 12.8 20.6 0.0095 14.9 4.8 3.0 3 0 0 3 3 3 0 ZIP Zinc transporter NTP_transf_2 PF01909.18 CDI84664.1 - 0.12 12.6 0.0 0.22 11.8 0.0 1.3 1 0 0 1 1 1 0 Nucleotidyltransferase domain Spore_coat_CotO PF14153.1 CDI84664.1 - 0.14 11.6 31.3 0.26 10.7 5.1 2.6 3 0 0 3 3 3 0 Spore coat protein CotO MRP-S31 PF15433.1 CDI84664.1 - 0.17 11.3 21.7 0.69 9.2 4.7 2.8 2 0 0 2 2 2 0 Mitochondrial 28S ribosomal protein S31 Peptidase_S49_N PF08496.5 CDI84664.1 - 0.33 10.7 16.3 0.87 9.3 5.0 2.4 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Raftlin PF15250.1 CDI84664.1 - 0.41 9.1 26.5 1.2 7.6 5.2 2.5 2 0 0 2 2 2 0 Raftlin GAGA_bind PF06217.7 CDI84664.1 - 0.6 10.0 23.0 1.3 8.9 4.9 2.3 2 0 0 2 2 2 0 GAGA binding protein-like family Nop53 PF07767.6 CDI84664.1 - 0.77 8.6 28.3 1.7 7.5 8.4 2.4 2 0 0 2 2 2 0 Nop53 (60S ribosomal biogenesis) DUF3801 PF12687.2 CDI84664.1 - 0.82 9.2 24.5 0.038 13.5 2.8 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3801) eIF-3_zeta PF05091.7 CDI84664.1 - 1.9 7.0 25.7 0.36 9.3 4.7 2.2 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Vfa1 PF08432.5 CDI84664.1 - 3.4 7.6 31.5 3.9 7.4 5.2 3.2 3 0 0 3 3 3 0 AAA-ATPase Vps4-associated protein 1 Band_3_cyto PF07565.8 CDI84664.1 - 4.6 6.6 26.3 2.9 7.3 4.6 2.4 2 0 0 2 2 2 0 Band 3 cytoplasmic domain FimP PF09766.4 CDI84664.1 - 5.1 6.0 38.7 0.6 9.1 9.8 2.3 2 0 0 2 2 2 0 Fms-interacting protein FLO_LFY PF01698.11 CDI84664.1 - 6.3 5.5 30.6 1.2 7.9 6.7 2.8 3 0 0 3 3 3 0 Floricaula / Leafy protein DUF4557 PF15101.1 CDI84664.1 - 7.8 6.2 34.4 2.4 7.9 7.3 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4557) PAT1 PF09770.4 CDI84664.1 - 9.1 4.3 48.9 0.92 7.6 13.1 2.2 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 DUF3685 PF12452.3 CDI84666.1 - 0.13 11.3 0.4 0.24 10.5 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3685) Acid_PPase PF12689.2 CDI84668.1 - 0.036 13.6 8.1 0.05 13.2 5.6 1.4 1 0 0 1 1 1 0 Acid Phosphatase DUF2052 PF09747.4 CDI84668.1 - 2.3 8.0 26.5 4.2 7.2 2.4 2.3 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) FYDLN_acid PF09538.5 CDI84668.1 - 8.8 6.9 7.6 22 5.6 1.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) GATase PF00117.23 CDI84669.1 - 0.02 14.3 0.2 0.021 14.2 0.2 1.2 1 0 0 1 1 1 0 Glutamine amidotransferase class-I DUF2828 PF11443.3 CDI84670.1 - 0.00029 19.1 1.9 0.00031 19.0 1.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF2828) Raftlin PF15250.1 CDI84670.1 - 0.001 17.6 4.7 0.0012 17.5 3.2 1.1 1 0 0 1 1 1 1 Raftlin Suf PF05843.9 CDI84670.1 - 0.002 17.8 7.5 0.0025 17.5 5.2 1.3 1 0 0 1 1 1 1 Suppressor of forked protein (Suf) YqfQ PF14181.1 CDI84670.1 - 0.0025 17.8 12.2 0.0025 17.8 8.5 2.1 2 0 0 2 2 2 1 YqfQ-like protein Het-C PF07217.6 CDI84670.1 - 0.01 14.0 2.8 0.011 13.9 1.9 1.1 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C ERO1 PF04137.10 CDI84670.1 - 0.011 14.7 5.6 0.014 14.4 3.9 1.1 1 0 0 1 1 1 0 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) Ycf1 PF05758.7 CDI84670.1 - 0.014 13.1 9.2 0.018 12.8 6.4 1.1 1 0 0 1 1 1 0 Ycf1 OATP PF03137.15 CDI84670.1 - 0.034 12.2 5.0 0.049 11.6 3.5 1.2 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family AAA_23 PF13476.1 CDI84670.1 - 0.035 14.4 13.7 0.045 14.0 9.5 1.2 1 0 0 1 1 1 0 AAA domain Spore_YhcN_YlaJ PF09580.5 CDI84670.1 - 0.051 13.6 8.4 0.065 13.3 5.8 1.2 1 0 0 1 1 1 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) DUF822 PF05687.8 CDI84670.1 - 0.12 12.7 6.6 0.035 14.4 2.1 1.7 2 0 0 2 2 2 0 Plant protein of unknown function (DUF822) Dynamin_N PF00350.18 CDI84670.1 - 0.14 11.9 4.7 0.21 11.4 3.2 1.3 1 0 0 1 1 1 0 Dynamin family Baculo_PP31 PF05311.6 CDI84670.1 - 0.16 11.2 9.4 0.26 10.5 6.5 1.3 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) DUF2360 PF10152.4 CDI84670.1 - 0.16 12.2 12.7 0.49 10.6 4.0 2.1 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) Pex14_N PF04695.8 CDI84670.1 - 0.21 11.6 23.6 0.35 10.9 13.2 2.1 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region RR_TM4-6 PF06459.7 CDI84670.1 - 0.22 11.3 13.4 0.082 12.7 7.2 1.6 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Hid1 PF12722.2 CDI84670.1 - 0.34 8.5 11.1 0.44 8.1 7.7 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein TraV PF09676.5 CDI84670.1 - 0.37 11.4 12.6 12 6.6 0.0 2.1 2 0 0 2 2 2 0 Type IV conjugative transfer system lipoprotein (TraV) Folate_carrier PF01770.13 CDI84670.1 - 0.42 9.0 9.2 0.05 12.1 3.1 1.6 2 0 0 2 2 2 0 Reduced folate carrier DUF3381 PF11861.3 CDI84670.1 - 0.48 9.9 16.9 0.83 9.1 11.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) CDC45 PF02724.9 CDI84670.1 - 0.49 8.3 13.9 0.76 7.7 9.6 1.3 1 0 0 1 1 1 0 CDC45-like protein DUF4557 PF15101.1 CDI84670.1 - 0.52 10.1 22.0 0.94 9.2 15.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) XAP5 PF04921.9 CDI84670.1 - 0.63 9.5 12.0 0.69 9.4 7.3 1.7 2 0 0 2 2 2 0 XAP5, circadian clock regulator FAM91_C PF14648.1 CDI84670.1 - 0.64 8.7 0.0 0.64 8.7 0.0 2.0 1 1 1 2 2 1 0 FAM91 C-terminus TRAP_alpha PF03896.11 CDI84670.1 - 0.65 8.9 6.7 0.35 9.8 2.0 1.9 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit FAM176 PF14851.1 CDI84670.1 - 0.69 9.5 6.0 1.3 8.7 4.1 1.5 1 0 0 1 1 1 0 FAM176 family AIF_C PF14721.1 CDI84670.1 - 0.69 10.1 16.5 0.16 12.1 5.9 2.1 2 0 0 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term FimP PF09766.4 CDI84670.1 - 0.82 8.6 26.8 1.4 7.8 18.6 1.3 1 0 0 1 1 1 0 Fms-interacting protein CPSF100_C PF13299.1 CDI84670.1 - 0.86 9.7 11.4 0.65 10.1 6.3 1.7 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal Pex16 PF08610.5 CDI84670.1 - 0.86 8.5 9.1 1.1 8.1 6.3 1.2 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) Mem_trans PF03547.13 CDI84670.1 - 1.1 7.4 4.6 1.8 6.7 3.2 1.3 1 0 0 1 1 1 0 Membrane transport protein TraH_2 PF06871.6 CDI84670.1 - 1.1 8.6 13.2 0.081 12.3 4.6 1.9 2 0 0 2 2 2 0 TraH_2 DUF912 PF06024.7 CDI84670.1 - 1.2 9.2 11.3 1 9.4 5.0 2.3 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DHHW PF14286.1 CDI84670.1 - 1.3 8.3 12.6 1 8.6 6.1 1.9 2 0 0 2 2 2 0 DHHW protein DDHD PF02862.12 CDI84670.1 - 1.3 8.7 15.4 0.26 11.0 8.1 1.6 2 0 0 2 2 2 0 DDHD domain Glyco_transf_15 PF01793.11 CDI84670.1 - 1.4 7.7 13.4 2.1 7.2 9.3 1.2 1 0 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase Anoctamin PF04547.7 CDI84670.1 - 1.7 7.2 5.9 2.1 6.9 4.1 1.1 1 0 0 1 1 1 0 Calcium-activated chloride channel RIC3 PF15361.1 CDI84670.1 - 1.7 8.8 12.5 1.3 9.2 7.0 1.8 2 0 0 2 2 2 0 Resistance to inhibitors of cholinesterase homologue 3 Gti1_Pac2 PF09729.4 CDI84670.1 - 2.1 8.1 9.7 3.7 7.4 6.7 1.3 1 0 0 1 1 1 0 Gti1/Pac2 family Afi1 PF07792.7 CDI84670.1 - 2.2 8.2 14.6 4.4 7.3 10.1 1.4 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking eIF-3_zeta PF05091.7 CDI84670.1 - 2.7 6.5 18.3 3.8 6.0 12.7 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Kei1 PF08552.6 CDI84670.1 - 2.9 7.5 15.5 1.6 8.3 5.6 2.1 2 0 0 2 2 2 0 Inositolphosphorylceramide synthase subunit Kei1 DUF3530 PF12048.3 CDI84670.1 - 3 6.7 29.7 0.042 12.8 1.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3530) DUF2215 PF10225.4 CDI84670.1 - 3.4 7.0 4.9 4.9 6.5 3.4 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) Paf1 PF03985.8 CDI84670.1 - 3.5 6.2 24.5 5.1 5.7 17.0 1.1 1 0 0 1 1 1 0 Paf1 Herpes_DNAp_acc PF04929.7 CDI84670.1 - 3.6 6.4 11.2 5 5.9 7.8 1.3 1 1 0 1 1 1 0 Herpes DNA replication accessory factor G0-G1_switch_2 PF15103.1 CDI84670.1 - 3.7 7.8 12.5 1.6 8.9 6.3 2.1 2 0 0 2 2 2 0 G0/G1 switch protein 2 DUF1764 PF08576.5 CDI84670.1 - 4 8.2 20.6 0.71 10.6 11.4 1.7 2 0 0 2 2 1 0 Eukaryotic protein of unknown function (DUF1764) Peptidase_S49_N PF08496.5 CDI84670.1 - 4.5 7.0 13.0 8.7 6.1 9.0 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal GOLD_2 PF13897.1 CDI84670.1 - 5.2 7.2 8.9 1.3 9.3 4.0 1.5 2 0 0 2 2 1 0 Golgi-dynamics membrane-trafficking TLP-20 PF06088.6 CDI84670.1 - 5.3 6.6 11.2 0.48 10.0 4.5 1.6 2 0 0 2 2 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) CRF1 PF10380.4 CDI84670.1 - 5.4 7.3 8.9 5.1 7.4 4.8 1.9 2 0 0 2 2 2 0 Transcription factor CRF1 Endonuc_Holl PF10107.4 CDI84670.1 - 5.7 6.6 14.1 10 5.7 9.8 1.4 1 0 0 1 1 1 0 Endonuclease related to archaeal Holliday junction resolvase G-alpha PF00503.15 CDI84670.1 - 5.7 5.5 17.1 8.5 4.9 11.9 1.2 1 0 0 1 1 1 0 G-protein alpha subunit DUF2126 PF09899.4 CDI84670.1 - 6.4 4.6 11.2 9.1 4.1 7.8 1.2 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) DUF3260 PF11658.3 CDI84670.1 - 6.8 4.7 13.9 2 6.4 6.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3260) DUF4512 PF14975.1 CDI84670.1 - 8.3 7.3 11.5 1.1 10.1 3.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4512) Amastin PF07344.6 CDI84671.1 - 0.065 12.8 0.8 0.096 12.2 0.6 1.3 1 0 0 1 1 1 0 Amastin surface glycoprotein O-antigen_lig PF13425.1 CDI84671.1 - 0.1 12.5 0.1 0.14 12.1 0.1 1.1 1 0 0 1 1 1 0 O-antigen ligase like membrane protein Herpes_gE PF02480.11 CDI84671.1 - 0.14 10.3 5.0 0.18 10.0 3.4 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Bul1_N PF04425.7 CDI84672.1 - 0.53 8.7 13.6 0.6 8.5 9.5 1.0 1 0 0 1 1 1 0 Bul1 N terminus DUF1510 PF07423.6 CDI84672.1 - 1.2 8.3 8.1 1.4 8.2 5.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) CDC45 PF02724.9 CDI84672.1 - 1.8 6.4 9.5 2 6.3 6.6 1.0 1 0 0 1 1 1 0 CDC45-like protein Alpha_GJ PF03229.8 CDI84672.1 - 2.4 8.5 6.3 3.1 8.1 4.4 1.3 1 0 0 1 1 1 0 Alphavirus glycoprotein J DUF2413 PF10310.4 CDI84672.1 - 4 6.1 10.8 4.2 6.0 7.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) SprA-related PF12118.3 CDI84672.1 - 4.3 6.5 19.6 4.9 6.3 13.6 1.0 1 0 0 1 1 1 0 SprA-related family DUF572 PF04502.8 CDI84672.1 - 4.5 6.4 12.0 5.3 6.1 8.3 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) SOG2 PF10428.4 CDI84672.1 - 4.5 5.8 20.6 4.8 5.7 14.3 1.0 1 0 0 1 1 1 0 RAM signalling pathway protein GEMIN8 PF15348.1 CDI84672.1 - 4.6 7.2 10.0 5.2 7.0 6.9 1.0 1 0 0 1 1 1 0 Gemini of Cajal bodies-associated protein 8 Striatin PF08232.7 CDI84672.1 - 5.5 7.3 9.1 6.7 7.0 6.3 1.1 1 0 0 1 1 1 0 Striatin family Utp14 PF04615.8 CDI84672.1 - 5.9 4.9 9.1 6.7 4.7 6.3 1.0 1 0 0 1 1 1 0 Utp14 protein RP-C_C PF11800.3 CDI84672.1 - 6 6.5 9.4 6.5 6.3 6.5 1.1 1 0 0 1 1 1 0 Replication protein C C-terminal region Apt1 PF10351.4 CDI84672.1 - 6.3 5.5 23.1 7.2 5.3 16.0 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain SUFU_C PF12470.3 CDI84672.1 - 6.5 6.3 7.4 7.4 6.1 5.1 1.1 1 0 0 1 1 1 0 Suppressor of Fused Gli/Ci N terminal binding domain DUF3362 PF11842.3 CDI84672.1 - 7.1 6.5 6.7 8.7 6.2 4.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3362) DUF2201_N PF13203.1 CDI84672.1 - 7.8 5.5 8.3 9.3 5.3 5.7 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain Zip PF02535.17 CDI84672.1 - 8 5.3 8.0 8.9 5.2 5.5 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter Pex14_N PF04695.8 CDI84672.1 - 8.5 6.4 23.8 16 5.5 16.5 1.5 1 1 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Macoilin PF09726.4 CDI84672.1 - 8.6 4.4 28.9 9.3 4.3 20.1 1.0 1 0 0 1 1 1 0 Transmembrane protein Shadoo PF14999.1 CDI84673.1 - 0.033 14.0 5.4 0.056 13.2 3.7 1.5 1 0 0 1 1 1 0 Shadow of prion protein, neuroprotective Bud13 PF09736.4 CDI84673.1 - 0.038 14.2 19.7 0.044 14.0 13.7 1.3 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex Gag_spuma PF03276.9 CDI84673.1 - 0.064 11.5 32.9 0.066 11.5 22.8 1.1 1 0 0 1 1 1 0 Spumavirus gag protein U79_P34 PF03064.11 CDI84673.1 - 0.071 12.6 13.0 0.086 12.3 9.0 1.1 1 0 0 1 1 1 0 HSV U79 / HCMV P34 DUF1510 PF07423.6 CDI84673.1 - 0.073 12.4 17.7 0.074 12.4 12.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Spore_coat_CotO PF14153.1 CDI84673.1 - 0.079 12.4 24.2 0.092 12.1 16.8 1.3 1 0 0 1 1 1 0 Spore coat protein CotO AAA_23 PF13476.1 CDI84673.1 - 0.086 13.1 20.4 0.085 13.1 14.2 1.1 1 0 0 1 1 1 0 AAA domain HemX PF04375.9 CDI84673.1 - 0.11 11.0 42.1 0.14 10.7 29.2 1.0 1 0 0 1 1 1 0 HemX Med15 PF09606.5 CDI84673.1 - 0.14 10.3 69.9 0.19 9.9 48.4 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal CDC45 PF02724.9 CDI84673.1 - 0.14 10.1 13.2 0.14 10.2 9.2 1.0 1 0 0 1 1 1 0 CDC45-like protein Pox_Ag35 PF03286.9 CDI84673.1 - 0.16 11.4 11.4 0.18 11.2 7.9 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein BTV_NS2 PF04514.7 CDI84673.1 - 0.23 10.3 12.7 0.22 10.3 8.8 1.0 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 eIF-3_zeta PF05091.7 CDI84673.1 - 0.25 9.9 22.8 0.24 9.9 15.8 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) HlyD_2 PF12700.2 CDI84673.1 - 0.28 10.2 17.6 0.27 10.3 12.2 1.1 1 0 0 1 1 1 0 HlyD family secretion protein APG6 PF04111.7 CDI84673.1 - 0.29 10.1 18.3 0.29 10.1 12.7 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Ctr PF04145.10 CDI84673.1 - 0.3 11.1 16.2 1.6 8.7 11.2 1.8 1 1 0 1 1 1 0 Ctr copper transporter family Ribosomal_60s PF00428.14 CDI84673.1 - 0.31 11.4 17.0 0.75 10.2 11.8 1.7 1 0 0 1 1 1 0 60s Acidic ribosomal protein Peptidase_S49_N PF08496.5 CDI84673.1 - 0.31 10.8 14.1 0.44 10.3 9.8 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal BORG_CEP PF14957.1 CDI84673.1 - 0.33 11.8 11.7 0.41 11.5 8.1 1.3 1 0 0 1 1 1 0 Cdc42 effector Pal1 PF08316.6 CDI84673.1 - 0.36 11.2 12.3 0.5 10.8 8.6 1.2 1 0 0 1 1 1 0 Pal1 cell morphology protein Asp-B-Hydro_N PF05279.6 CDI84673.1 - 0.4 10.5 12.0 0.41 10.4 8.3 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region OATP PF03137.15 CDI84673.1 - 0.41 8.6 9.8 0.46 8.4 6.8 1.3 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family POP1 PF06978.6 CDI84673.1 - 0.42 10.2 14.6 0.54 9.8 10.2 1.2 1 0 0 1 1 1 0 Ribonucleases P/MRP protein subunit POP1 GPCR_chapero_1 PF11904.3 CDI84673.1 - 0.44 9.6 12.1 0.41 9.7 8.4 1.1 1 0 0 1 1 1 0 GPCR-chaperone Hid1 PF12722.2 CDI84673.1 - 0.46 8.0 19.5 0.49 8.0 13.5 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein PPP4R2 PF09184.6 CDI84673.1 - 0.47 9.9 13.5 0.49 9.8 9.4 1.0 1 0 0 1 1 1 0 PPP4R2 Raftlin PF15250.1 CDI84673.1 - 0.48 8.9 17.2 0.49 8.8 11.9 1.0 1 0 0 1 1 1 0 Raftlin NARP1 PF12569.3 CDI84673.1 - 0.63 8.7 20.5 0.69 8.5 14.2 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 TT_ORF1 PF02956.9 CDI84673.1 - 0.63 8.4 13.5 0.61 8.4 9.3 1.0 1 0 0 1 1 1 0 TT viral orf 1 Ycf1 PF05758.7 CDI84673.1 - 0.68 7.5 17.6 0.65 7.6 12.2 1.0 1 0 0 1 1 1 0 Ycf1 Band_3_cyto PF07565.8 CDI84673.1 - 0.71 9.3 19.7 0.87 9.0 13.7 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain DUF2232 PF09991.4 CDI84673.1 - 0.73 8.7 9.5 0.99 8.3 6.6 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) Tfb4 PF03850.9 CDI84673.1 - 0.75 8.9 11.1 0.79 8.9 7.7 1.1 1 0 0 1 1 1 0 Transcription factor Tfb4 Dynamin_N PF00350.18 CDI84673.1 - 0.78 9.5 7.7 0.86 9.4 5.3 1.2 1 0 0 1 1 1 0 Dynamin family SAGA-Tad1 PF12767.2 CDI84673.1 - 0.79 9.3 22.4 0.94 9.0 15.5 1.2 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit Peptidase_S15 PF02129.13 CDI84673.1 - 0.88 8.9 18.9 1 8.7 13.1 1.1 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) FAM60A PF15396.1 CDI84673.1 - 0.95 9.1 14.0 1.1 8.9 9.7 1.2 1 0 0 1 1 1 0 Protein Family FAM60A DUF2126 PF09899.4 CDI84673.1 - 0.97 7.3 12.7 0.99 7.3 8.8 1.1 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) CPSF100_C PF13299.1 CDI84673.1 - 1 9.4 15.2 1.2 9.2 10.5 1.3 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal CobT PF06213.7 CDI84673.1 - 1.1 8.3 16.9 1.2 8.2 11.7 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT FNIP_N PF14636.1 CDI84673.1 - 1.1 9.7 18.1 1.5 9.3 12.5 1.4 1 0 0 1 1 1 0 Folliculin-interacting protein N-terminus RR_TM4-6 PF06459.7 CDI84673.1 - 1.2 8.9 19.8 1.2 8.9 13.7 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 FHIPEP PF00771.15 CDI84673.1 - 1.2 7.3 13.7 1.4 7.1 9.5 1.2 1 0 0 1 1 1 0 FHIPEP family GAGA_bind PF06217.7 CDI84673.1 - 1.2 8.9 17.5 1.3 8.8 12.1 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family DUF3381 PF11861.3 CDI84673.1 - 1.3 8.4 16.6 1.6 8.2 11.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) PIH1 PF08190.7 CDI84673.1 - 1.3 8.3 23.9 1.2 8.4 16.6 1.2 1 0 0 1 1 1 0 pre-RNA processing PIH1/Nop17 Baculo_PP31 PF05311.6 CDI84673.1 - 1.4 8.1 16.8 1.6 7.9 11.6 1.2 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) AUX_IAA PF02309.11 CDI84673.1 - 1.8 8.2 15.4 1.9 8.1 10.6 1.2 1 0 0 1 1 1 0 AUX/IAA family Gastrin PF00918.12 CDI84673.1 - 1.8 9.3 27.1 2.5 8.9 18.8 1.3 1 0 0 1 1 1 0 Gastrin/cholecystokinin family Nop53 PF07767.6 CDI84673.1 - 2 7.3 27.0 2.1 7.2 18.7 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) DUF4045 PF13254.1 CDI84673.1 - 2.1 7.5 20.6 2.2 7.5 14.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) FLO_LFY PF01698.11 CDI84673.1 - 2.2 7.0 21.6 2.6 6.8 14.9 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein Tim54 PF11711.3 CDI84673.1 - 2.2 6.7 12.6 2.3 6.7 8.8 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 MARCKS PF02063.12 CDI84673.1 - 2.4 7.9 24.5 3 7.6 17.0 1.1 1 0 0 1 1 1 0 MARCKS family Hom_end_hint PF05203.11 CDI84673.1 - 2.4 7.8 10.8 2.8 7.6 7.5 1.3 1 0 0 1 1 1 0 Hom_end-associated Hint DUF3450 PF11932.3 CDI84673.1 - 2.4 7.3 39.5 3 7.0 27.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Spore_YhcN_YlaJ PF09580.5 CDI84673.1 - 2.4 8.2 18.2 2.6 8.1 12.6 1.2 1 0 0 1 1 1 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) Cyto_heme_lyase PF01265.12 CDI84673.1 - 2.8 7.4 19.8 3.2 7.2 13.7 1.1 1 0 0 1 1 1 0 Cytochrome c/c1 heme lyase SpoVR PF04293.8 CDI84673.1 - 2.9 6.1 17.3 3.2 6.0 12.0 1.1 1 0 0 1 1 1 0 SpoVR like protein MgsA_C PF12002.3 CDI84673.1 - 2.9 7.5 14.9 3.7 7.2 10.3 1.1 1 0 0 1 1 1 0 MgsA AAA+ ATPase C terminal Bac_luciferase PF00296.15 CDI84673.1 - 3.5 6.6 11.2 4.2 6.3 7.8 1.1 1 0 0 1 1 1 0 Luciferase-like monooxygenase Lin-8 PF03353.10 CDI84673.1 - 3.7 6.7 21.0 3.7 6.7 14.5 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Cellulose_synt PF03552.9 CDI84673.1 - 3.8 5.6 8.1 4 5.6 5.6 1.0 1 0 0 1 1 1 0 Cellulose synthase DUF2072 PF09845.4 CDI84673.1 - 4 7.3 9.3 4.8 7.1 6.5 1.3 1 0 0 1 1 1 0 Zn-ribbon containing protein (DUF2072) SpaB_C PF14028.1 CDI84673.1 - 4 6.9 12.8 5.2 6.5 8.9 1.1 1 0 0 1 1 1 0 SpaB C-terminal domain FAM176 PF14851.1 CDI84673.1 - 4 7.0 11.5 6.4 6.4 8.0 1.4 1 0 0 1 1 1 0 FAM176 family CDK5_activator PF03261.10 CDI84673.1 - 4.1 6.6 19.5 4.4 6.5 13.5 1.0 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein Neur_chan_memb PF02932.11 CDI84673.1 - 4.1 7.2 14.0 4.3 7.1 9.7 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region TFIIA PF03153.8 CDI84673.1 - 4.2 7.1 44.8 4.6 7.0 31.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DDHD PF02862.12 CDI84673.1 - 4.3 7.0 20.5 4.7 6.9 14.2 1.1 1 0 0 1 1 1 0 DDHD domain DUF822 PF05687.8 CDI84673.1 - 4.4 7.6 14.4 5.3 7.4 10.0 1.2 1 0 0 1 1 1 0 Plant protein of unknown function (DUF822) Mem_trans PF03547.13 CDI84673.1 - 4.4 5.4 8.1 4.4 5.4 5.6 1.1 1 0 0 1 1 1 0 Membrane transport protein SID-1_RNA_chan PF13965.1 CDI84673.1 - 4.4 5.3 9.2 4.5 5.3 6.3 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 NPR3 PF03666.8 CDI84673.1 - 4.5 5.7 18.1 5.1 5.5 12.6 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF4446 PF14584.1 CDI84673.1 - 4.5 7.0 9.4 5.7 6.7 6.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) DUF2149 PF09919.4 CDI84673.1 - 4.7 7.3 15.8 8.7 6.5 11.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2149) Zip PF02535.17 CDI84673.1 - 4.8 6.0 10.3 5.4 5.9 7.1 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter F-protein PF00469.15 CDI84673.1 - 5.5 6.3 16.0 6.5 6.0 11.1 1.2 1 0 0 1 1 1 0 Negative factor, (F-Protein) or Nef YjgP_YjgQ PF03739.9 CDI84673.1 - 5.5 5.6 9.2 6.2 5.4 6.4 1.2 1 0 0 1 1 1 0 Predicted permease YjgP/YjgQ family PAT1 PF09770.4 CDI84673.1 - 6 4.9 54.1 6.2 4.9 37.5 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF2215 PF10225.4 CDI84673.1 - 6.2 6.1 11.3 7.3 5.9 7.8 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) DUF605 PF04652.11 CDI84673.1 - 6.3 6.0 30.1 6.3 6.0 20.9 1.1 1 0 0 1 1 1 0 Vta1 like Peptidase_U57 PF05582.7 CDI84673.1 - 6.4 5.6 15.4 7.9 5.3 10.6 1.1 1 0 0 1 1 1 0 YabG peptidase U57 HGTP_anticodon2 PF12745.2 CDI84673.1 - 6.7 5.7 16.3 8.1 5.4 11.3 1.2 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs DUF1980 PF09323.5 CDI84673.1 - 7.3 6.2 13.5 9 5.9 9.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) Gti1_Pac2 PF09729.4 CDI84673.1 - 7.6 6.3 16.1 11 5.8 11.2 1.2 1 0 0 1 1 1 0 Gti1/Pac2 family Paramyxo_ncap PF00973.14 CDI84673.1 - 8.2 4.9 17.0 8.6 4.9 11.8 1.0 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Herpes_DNAp_acc PF04929.7 CDI84673.1 - 8.3 5.2 15.8 8.8 5.1 10.9 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor DDRGK PF09756.4 CDI84673.1 - 8.4 5.7 29.8 12 5.2 20.7 1.2 1 0 0 1 1 1 0 DDRGK domain DHHW PF14286.1 CDI84673.1 - 8.5 5.5 16.6 8.8 5.5 11.5 1.1 1 0 0 1 1 1 0 DHHW protein DUF4220 PF13968.1 CDI84673.1 - 8.7 5.3 9.1 9.2 5.2 6.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4220) DUF853 PF05872.7 CDI84673.1 - 9.6 4.4 17.3 12 4.1 12.0 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) DUF3523 PF12037.3 CDI84673.1 - 10 5.0 33.0 12 4.7 22.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3523) CAF-1_p150 PF11600.3 CDI84674.1 - 0.00036 19.9 36.5 0.00047 19.6 25.3 1.1 1 0 0 1 1 1 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal SprA-related PF12118.3 CDI84674.1 - 0.0079 15.5 62.2 0.0096 15.2 43.1 1.1 1 0 0 1 1 1 1 SprA-related family AAA_23 PF13476.1 CDI84674.1 - 0.92 9.7 28.3 1.2 9.3 19.6 1.1 1 0 0 1 1 1 0 AAA domain SR-25 PF10500.4 CDI84674.1 - 1.1 8.7 52.7 0.024 14.0 20.3 2.1 1 1 1 2 2 2 0 Nuclear RNA-splicing-associated protein SOBP PF15279.1 CDI84674.1 - 1.7 8.9 39.7 2.2 8.5 27.5 1.0 1 0 0 1 1 1 0 Sine oculis-binding protein DUF4551 PF15087.1 CDI84674.1 - 2.9 6.1 33.5 3.5 5.8 23.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Utp14 PF04615.8 CDI84674.1 - 6.8 4.7 36.6 8.2 4.4 25.4 1.0 1 0 0 1 1 1 0 Utp14 protein PAT1 PF09770.4 CDI84674.1 - 7.8 4.6 73.5 9.3 4.3 50.9 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Pex14_N PF04695.8 CDI84675.1 - 0.0055 16.7 3.4 0.0055 16.7 2.4 3.5 2 1 1 3 3 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region RAB3GAP2_N PF14655.1 CDI84675.1 - 0.0061 15.6 6.1 0.0061 15.6 4.2 3.5 3 2 0 3 3 1 1 Rab3 GTPase-activating protein regulatory subunit N-terminus DUF3449 PF11931.3 CDI84675.1 - 0.019 14.5 17.6 0.16 11.4 0.5 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF3449) Peptidase_S49_N PF08496.5 CDI84675.1 - 0.023 14.5 20.9 1.1 8.9 0.2 3.2 3 0 0 3 3 3 0 Peptidase family S49 N-terminal Med15 PF09606.5 CDI84675.1 - 0.25 9.4 103.6 0.032 12.4 12.0 3.0 3 0 0 3 3 3 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF4366 PF14283.1 CDI84675.1 - 0.83 9.0 11.1 0.68 9.3 0.5 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4366) Nucleoside_tran PF01733.13 CDI84675.1 - 0.89 8.6 8.6 1.3 8.0 0.1 3.2 3 0 0 3 3 3 0 Nucleoside transporter Serinc PF03348.10 CDI84675.1 - 1.3 7.6 21.1 0.54 8.8 1.9 3.1 3 0 0 3 3 3 0 Serine incorporator (Serinc) Hom_end_hint PF05203.11 CDI84675.1 - 1.6 8.3 10.8 1.3 8.7 0.1 3.0 3 0 0 3 3 3 0 Hom_end-associated Hint AIF_C PF14721.1 CDI84675.1 - 2.1 8.6 17.7 6.4 7.0 1.5 3.2 3 0 0 3 3 3 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Dala_Dala_lig_N PF01820.16 CDI84675.1 - 2.4 8.5 12.3 2.8 8.2 0.5 3.2 3 0 0 3 3 3 0 D-ala D-ala ligase N-terminus FHIPEP PF00771.15 CDI84675.1 - 2.5 6.3 25.0 0.65 8.2 1.0 3.1 3 0 0 3 3 3 0 FHIPEP family DUF4557 PF15101.1 CDI84675.1 - 3.9 7.2 50.4 1.1 9.0 9.2 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4557) YfhO PF09586.5 CDI84675.1 - 4.3 5.2 16.1 0.29 9.0 0.9 2.9 3 0 0 3 3 3 0 Bacterial membrane protein YfhO DUF3371 PF11851.3 CDI84675.1 - 4.3 8.0 52.3 2.2 8.9 7.6 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF3371) Cellulose_synt PF03552.9 CDI84675.1 - 4.3 5.5 6.9 1.2 7.3 0.5 2.2 2 0 0 2 2 2 0 Cellulose synthase FimP PF09766.4 CDI84675.1 - 6.8 5.6 50.7 0.058 12.4 5.1 3.1 3 0 0 3 3 3 0 Fms-interacting protein TMEM51 PF15345.1 CDI84675.1 - 8.5 5.9 35.4 0.085 12.5 5.4 3.4 3 0 0 3 3 3 0 Transmembrane protein 51 Ribosomal_60s PF00428.14 CDI84676.1 - 0.0073 16.6 20.6 0.087 13.2 0.6 2.4 2 0 0 2 2 2 2 60s Acidic ribosomal protein PAT1 PF09770.4 CDI84676.1 - 0.59 8.3 100.1 0.85 7.7 69.4 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Glyco_hydro_3_C PF01915.17 CDI84677.1 - 0.48 9.9 3.2 0.69 9.3 2.2 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 3 C-terminal domain Shadoo PF14999.1 CDI84677.1 - 1.3 8.8 6.6 0.18 11.6 1.3 1.9 1 1 1 2 2 2 0 Shadow of prion protein, neuroprotective CRAL_TRIO PF00650.15 CDI84678.1 - 0.00051 19.5 0.0 0.00083 18.8 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain FEZ PF07763.8 CDI84678.1 - 0.0086 15.8 0.7 0.016 14.9 0.5 1.3 1 0 0 1 1 1 1 FEZ-like protein DUF690 PF05108.8 CDI84678.1 - 0.044 12.1 0.0 0.074 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF690) Ribosomal_60s PF00428.14 CDI84679.1 - 0.077 13.3 20.5 0.2 12.0 14.2 1.8 1 0 0 1 1 1 0 60s Acidic ribosomal protein SR-25 PF10500.4 CDI84680.1 - 0.048 13.1 16.1 0.052 13.0 11.1 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein CLP_protease PF00574.18 CDI84680.1 - 0.34 10.5 8.4 0.43 10.2 5.8 1.2 1 0 0 1 1 1 0 Clp protease XRCC4 PF06632.7 CDI84680.1 - 0.44 9.3 12.7 0.49 9.1 8.8 1.2 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 PBP_sp32 PF07222.7 CDI84680.1 - 0.73 8.9 21.1 0.83 8.7 14.6 1.3 1 0 0 1 1 1 0 Proacrosin binding protein sp32 DUF897 PF05982.7 CDI84680.1 - 0.81 8.4 3.4 1 8.1 2.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF897) Glt_symporter PF03616.9 CDI84680.1 - 0.94 7.8 5.0 1.1 7.7 3.4 1.2 1 0 0 1 1 1 0 Sodium/glutamate symporter DDHD PF02862.12 CDI84680.1 - 1.2 8.9 16.7 1.2 8.8 11.6 1.1 1 0 0 1 1 1 0 DDHD domain Gag_spuma PF03276.9 CDI84680.1 - 1.3 7.2 26.4 1.3 7.3 18.3 1.2 1 0 0 1 1 1 0 Spumavirus gag protein TraT PF05818.7 CDI84680.1 - 1.6 8.1 13.0 2 7.7 9.0 1.2 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein PGA_cap PF09587.5 CDI84680.1 - 1.7 7.9 11.8 2.2 7.5 8.2 1.1 1 0 0 1 1 1 0 Bacterial capsule synthesis protein PGA_cap DUF4220 PF13968.1 CDI84680.1 - 2.5 7.1 9.5 2.7 7.0 6.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4220) Cellulose_synt PF03552.9 CDI84680.1 - 2.6 6.2 8.7 2.7 6.1 6.0 1.0 1 0 0 1 1 1 0 Cellulose synthase HemX PF04375.9 CDI84680.1 - 2.8 6.4 29.8 3.5 6.1 20.7 1.1 1 0 0 1 1 1 0 HemX Chorion_S16 PF05836.7 CDI84680.1 - 3 7.7 9.7 4.1 7.3 6.8 1.3 1 0 0 1 1 1 0 Chorion protein S16 PAT1 PF09770.4 CDI84680.1 - 4 5.5 37.6 4 5.5 26.0 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 FLO_LFY PF01698.11 CDI84680.1 - 4.1 6.1 18.4 4.3 6.0 12.8 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein RNA_pol_Rpb1_5 PF04998.12 CDI84680.1 - 5 6.2 13.6 6 6.0 9.5 1.0 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 Serinc PF03348.10 CDI84680.1 - 6.1 5.4 14.2 6 5.4 9.9 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) SprA-related PF12118.3 CDI84680.1 - 6.4 6.0 43.9 8.3 5.6 30.4 1.2 1 0 0 1 1 1 0 SprA-related family Med19 PF10278.4 CDI84680.1 - 7.9 6.1 16.7 9 5.9 11.6 1.2 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 DUF2215 PF10225.4 CDI84680.1 - 8 5.8 8.2 8.5 5.7 5.6 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) Paf1 PF03985.8 CDI84680.1 - 9.2 4.8 24.4 9.9 4.7 16.9 1.0 1 0 0 1 1 1 0 Paf1 Peptidase_U57 PF05582.7 CDI84680.1 - 9.6 5.0 15.2 11 4.9 10.5 1.1 1 0 0 1 1 1 0 YabG peptidase U57 CAF-1_p150 PF11600.3 CDI84681.1 - 0.012 14.9 21.7 0.014 14.7 15.0 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal BRF1 PF07741.8 CDI84681.1 - 0.014 15.6 16.0 0.019 15.1 11.1 1.3 1 0 0 1 1 1 0 Brf1-like TBP-binding domain DUF4355 PF14265.1 CDI84681.1 - 0.015 15.2 17.1 0.018 14.9 11.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4355) Acetate_kinase PF00871.12 CDI84681.1 - 0.019 13.5 4.2 0.021 13.3 2.9 1.0 1 0 0 1 1 1 0 Acetokinase family DUF1764 PF08576.5 CDI84681.1 - 0.049 14.4 15.6 0.066 14.0 10.8 1.3 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) DUF1645 PF07816.6 CDI84681.1 - 0.053 13.9 14.7 0.064 13.7 10.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1645) DevR PF01905.11 CDI84681.1 - 0.063 12.1 5.9 0.074 11.8 4.1 1.1 1 0 0 1 1 1 0 CRISPR-associated negative auto-regulator DevR/Csa2 DUF3987 PF13148.1 CDI84681.1 - 0.073 11.6 8.6 0.084 11.4 6.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) DUF4557 PF15101.1 CDI84681.1 - 0.11 12.3 26.6 0.12 12.2 18.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) DUF4603 PF15376.1 CDI84681.1 - 0.16 9.1 15.9 0.17 9.0 11.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) FimP PF09766.4 CDI84681.1 - 0.2 10.6 27.7 0.25 10.3 19.2 1.2 1 0 0 1 1 1 0 Fms-interacting protein Lipoprotein_X PF03305.8 CDI84681.1 - 0.27 10.5 16.3 0.34 10.2 11.3 1.1 1 0 0 1 1 1 0 Mycoplasma MG185/MG260 protein PAT1 PF09770.4 CDI84681.1 - 0.27 9.4 39.9 0.29 9.3 27.6 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 eIF-3_zeta PF05091.7 CDI84681.1 - 0.31 9.6 22.1 0.32 9.5 15.4 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF4011 PF13195.1 CDI84681.1 - 0.37 10.7 10.2 0.45 10.5 7.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4011) RR_TM4-6 PF06459.7 CDI84681.1 - 0.37 10.6 14.3 0.41 10.5 9.9 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SprA-related PF12118.3 CDI84681.1 - 0.39 9.9 38.6 0.49 9.6 26.7 1.1 1 0 0 1 1 1 0 SprA-related family Baculo_PP31 PF05311.6 CDI84681.1 - 0.45 9.7 17.0 0.52 9.5 11.8 1.1 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) Peptidase_S15 PF02129.13 CDI84681.1 - 0.46 9.8 12.7 0.47 9.8 8.8 1.1 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) DUF3306 PF11748.3 CDI84681.1 - 0.47 11.1 11.6 0.52 10.9 8.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3306) DUF913 PF06025.7 CDI84681.1 - 0.47 9.1 10.1 0.53 8.9 7.0 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Ycf1 PF05758.7 CDI84681.1 - 0.51 7.9 16.0 0.54 7.8 11.1 1.0 1 0 0 1 1 1 0 Ycf1 SeqA PF03925.8 CDI84681.1 - 0.53 9.9 13.7 0.57 9.8 9.5 1.2 1 0 0 1 1 1 0 SeqA protein Asp-B-Hydro_N PF05279.6 CDI84681.1 - 0.56 10.0 10.0 0.61 9.8 6.9 1.0 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Dala_Dala_lig_N PF01820.16 CDI84681.1 - 0.67 10.2 9.6 0.84 9.9 6.6 1.3 1 0 0 1 1 1 0 D-ala D-ala ligase N-terminus Raftlin PF15250.1 CDI84681.1 - 0.93 7.9 19.6 0.97 7.8 13.6 1.0 1 0 0 1 1 1 0 Raftlin FLO_LFY PF01698.11 CDI84681.1 - 0.97 8.2 17.6 1.1 8.0 12.2 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein RNA_pol_Rpb1_5 PF04998.12 CDI84681.1 - 0.99 8.6 12.8 1 8.5 8.9 1.0 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 CagX PF03524.10 CDI84681.1 - 0.99 8.6 13.0 1.3 8.2 9.0 1.2 1 0 0 1 1 1 0 Conjugal transfer protein Spc7_N PF15402.1 CDI84681.1 - 1 7.3 25.1 1.2 7.0 17.4 1.0 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 FYDLN_acid PF09538.5 CDI84681.1 - 1 9.9 7.1 1.4 9.5 4.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) Peptidase_S49_N PF08496.5 CDI84681.1 - 1.1 9.0 18.0 1.3 8.7 12.5 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal AIF_C PF14721.1 CDI84681.1 - 1.3 9.3 19.1 1.7 8.8 13.2 1.3 1 1 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Tim54 PF11711.3 CDI84681.1 - 1.3 7.5 11.4 1.4 7.3 7.9 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Corona_nucleoca PF00937.13 CDI84681.1 - 1.4 7.7 22.8 1.6 7.5 15.8 1.0 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein Spore_coat_CotO PF14153.1 CDI84681.1 - 1.4 8.3 26.0 1.6 8.1 18.0 1.1 1 0 0 1 1 1 0 Spore coat protein CotO Zip PF02535.17 CDI84681.1 - 1.5 7.7 12.6 1.6 7.6 8.7 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Folate_carrier PF01770.13 CDI84681.1 - 1.7 7.0 11.7 1.7 7.0 8.1 1.1 1 0 0 1 1 1 0 Reduced folate carrier OATP PF03137.15 CDI84681.1 - 1.9 6.4 15.8 2 6.3 10.9 1.2 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family TFIIA PF03153.8 CDI84681.1 - 2 8.2 32.0 2.3 8.0 22.2 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit BTV_NS2 PF04514.7 CDI84681.1 - 2 7.2 14.4 2.2 7.0 10.0 1.0 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 K_trans PF02705.11 CDI84681.1 - 2.1 6.6 5.7 2.4 6.4 3.9 1.1 1 0 0 1 1 1 0 K+ potassium transporter Peptidase_U57 PF05582.7 CDI84681.1 - 2.1 7.2 13.5 2.3 7.0 9.4 1.1 1 0 0 1 1 1 0 YabG peptidase U57 DDHD PF02862.12 CDI84681.1 - 2.2 8.0 21.2 2.5 7.8 14.7 1.0 1 0 0 1 1 1 0 DDHD domain AUX_IAA PF02309.11 CDI84681.1 - 2.2 7.9 15.3 2.3 7.9 10.6 1.1 1 0 0 1 1 1 0 AUX/IAA family Dynamin_N PF00350.18 CDI84681.1 - 2.2 8.0 9.4 2.6 7.8 6.5 1.2 1 0 0 1 1 1 0 Dynamin family AAA_11 PF13086.1 CDI84681.1 - 2.4 7.6 17.1 2.8 7.4 11.9 1.2 1 0 0 1 1 1 0 AAA domain DUF1266 PF06889.6 CDI84681.1 - 2.8 7.7 12.7 3.4 7.4 8.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1266) Pneumo_phosprot PF02478.11 CDI84681.1 - 2.8 7.3 7.4 3 7.3 5.1 1.1 1 0 0 1 1 1 0 Pneumovirus phosphoprotein DUF4638 PF15472.1 CDI84681.1 - 2.8 7.4 12.5 3.1 7.3 8.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) SAGA-Tad1 PF12767.2 CDI84681.1 - 2.9 7.4 21.7 3.4 7.2 15.0 1.1 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit TT_ORF1 PF02956.9 CDI84681.1 - 3 6.1 20.0 2.9 6.2 13.9 1.0 1 0 0 1 1 1 0 TT viral orf 1 DUF2347 PF09804.4 CDI84681.1 - 3.2 6.9 12.4 3.6 6.7 8.6 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2347) SelP_N PF04592.9 CDI84681.1 - 3.2 7.0 23.9 3.9 6.7 16.6 1.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region LpxB PF02684.10 CDI84681.1 - 3.2 6.2 14.5 3.6 6.1 10.1 1.0 1 0 0 1 1 1 0 Lipid-A-disaccharide synthetase DDRGK PF09756.4 CDI84681.1 - 3.3 7.0 24.7 4.3 6.7 17.1 1.1 1 0 0 1 1 1 0 DDRGK domain DUF853 PF05872.7 CDI84681.1 - 3.7 5.8 13.5 3.9 5.7 9.4 1.0 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) DHHW PF14286.1 CDI84681.1 - 3.7 6.7 16.1 3.9 6.7 11.1 1.1 1 0 0 1 1 1 0 DHHW protein PPP4R2 PF09184.6 CDI84681.1 - 3.8 6.9 17.9 4.5 6.7 12.4 1.1 1 0 0 1 1 1 0 PPP4R2 DUF3260 PF11658.3 CDI84681.1 - 4 5.4 14.9 4.5 5.3 10.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3260) DUF1800 PF08811.6 CDI84681.1 - 4.2 6.1 20.9 4.6 6.0 14.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1800) SR-25 PF10500.4 CDI84681.1 - 4.3 6.7 33.2 12 5.2 23.0 1.6 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF4045 PF13254.1 CDI84681.1 - 4.3 6.4 19.4 5.1 6.2 13.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) DUF605 PF04652.11 CDI84681.1 - 4.6 6.5 26.7 5.5 6.2 18.5 1.0 1 0 0 1 1 1 0 Vta1 like Acyl-thio_N PF12590.3 CDI84681.1 - 5 7.6 10.6 6.2 7.2 7.3 1.1 1 0 0 1 1 1 0 Acyl-ATP thioesterase Sporozoite_P67 PF05642.6 CDI84681.1 - 5 4.8 9.1 5.7 4.6 6.3 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen CDC45 PF02724.9 CDI84681.1 - 5.3 4.9 22.3 6.1 4.7 15.4 1.0 1 0 0 1 1 1 0 CDC45-like protein FPN1 PF06963.7 CDI84681.1 - 5.6 5.2 10.6 5.9 5.1 7.4 1.1 1 0 0 1 1 1 0 Ferroportin1 (FPN1) Bud13 PF09736.4 CDI84681.1 - 5.7 7.1 24.2 7.4 6.8 16.8 1.2 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex CobT PF06213.7 CDI84681.1 - 6.1 5.8 13.1 7.2 5.6 9.1 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT CBP4 PF07960.6 CDI84681.1 - 6.3 6.4 24.6 8.6 6.0 17.1 1.2 1 0 0 1 1 1 0 CBP4 FHIPEP PF00771.15 CDI84681.1 - 6.7 4.9 10.9 8.1 4.6 7.5 1.2 1 0 0 1 1 1 0 FHIPEP family Cas1_AcylT PF07779.7 CDI84681.1 - 7.1 4.9 9.1 8.8 4.6 6.3 1.3 1 0 0 1 1 1 0 10 TM Acyl Transferase domain found in Cas1p DUF2126 PF09899.4 CDI84681.1 - 7.1 4.5 13.4 7.9 4.3 9.3 1.0 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) DUF3722 PF12519.3 CDI84681.1 - 7.2 5.7 12.2 9.2 5.3 8.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3722) Borrelia_P83 PF05262.6 CDI84681.1 - 9 4.4 19.1 9.4 4.3 13.2 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF3332 PF11810.3 CDI84681.1 - 9.1 5.9 9.3 9.9 5.7 6.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3332) Presenilin PF01080.12 CDI84681.1 - 9.5 4.9 15.4 10 4.8 10.7 1.0 1 0 0 1 1 1 0 Presenilin FAM60A PF15396.1 CDI84682.1 - 0.75 9.4 42.2 0.39 10.4 12.8 3.1 3 0 0 3 3 3 0 Protein Family FAM60A DUF1510 PF07423.6 CDI84682.1 - 3 7.1 56.8 1.9 7.7 16.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1510) DUF1654 PF07867.6 CDI84683.1 - 0.0076 15.5 0.5 1 8.7 0.0 2.6 2 1 1 3 3 3 2 Protein of unknown function (DUF1654) GIDA PF01134.17 CDI84684.1 - 1.1e-06 27.7 0.1 1.1e-06 27.7 0.1 3.2 3 0 0 3 3 3 2 Glucose inhibited division protein A SR-25 PF10500.4 CDI84684.1 - 0.00037 20.0 2.2 0.00037 20.0 1.5 6.8 5 1 1 6 6 6 1 Nuclear RNA-splicing-associated protein DUF2076 PF09849.4 CDI84684.1 - 0.0081 16.2 4.5 0.0081 16.2 3.1 4.5 3 2 1 4 4 4 2 Uncharacterized protein conserved in bacteria (DUF2076) CDK2AP PF09806.4 CDI84684.1 - 0.0092 16.2 7.4 0.0092 16.2 5.1 5.4 2 2 2 4 4 4 1 Cyclin-dependent kinase 2-associated protein HXXEE PF13787.1 CDI84684.1 - 1.1 9.5 2.6 48 4.3 0.0 3.7 3 1 1 4 4 4 0 Protein of unknown function with HXXEE motif Nha1_C PF08619.5 CDI84685.1 - 0.14 11.4 26.8 0.17 11.1 18.6 1.1 1 0 0 1 1 1 0 Alkali metal cation/H+ antiporter Nha1 C terminus PAT1 PF09770.4 CDI84685.1 - 0.24 9.5 69.1 0.26 9.4 47.9 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 AMP-binding PF00501.23 CDI84685.1 - 0.31 9.3 5.0 0.42 8.9 3.5 1.3 1 0 0 1 1 1 0 AMP-binding enzyme DUF4045 PF13254.1 CDI84685.1 - 0.62 9.2 26.2 0.7 9.1 18.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) TFIIA PF03153.8 CDI84685.1 - 0.67 9.7 46.5 0.82 9.4 32.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Med15 PF09606.5 CDI84685.1 - 0.83 7.7 88.8 1 7.5 61.5 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal SAGA-Tad1 PF12767.2 CDI84685.1 - 8.9 5.8 35.3 11 5.6 24.5 1.0 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit RR_TM4-6 PF06459.7 CDI84685.1 - 9.8 5.9 29.0 17 5.2 20.1 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Mucin PF01456.12 CDI84686.1 - 2.2 8.0 20.0 2.4 7.9 13.9 1.1 1 0 0 1 1 1 0 Mucin-like glycoprotein DGF-1_5 PF11038.3 CDI84686.1 - 2.6 7.1 10.8 3.1 6.9 7.5 1.0 1 0 0 1 1 1 0 Dispersed gene family protein 1 of Trypanosoma cruzi region 5 Sporozoite_P67 PF05642.6 CDI84686.1 - 3.7 5.2 7.3 3.9 5.2 5.1 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Med15 PF09606.5 CDI84688.1 - 4.9e-05 21.7 25.4 6e-05 21.4 17.6 1.1 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal ThiC PF01964.13 CDI84688.1 - 0.13 10.7 2.6 0.18 10.2 1.8 1.1 1 0 0 1 1 1 0 ThiC family DUF4557 PF15101.1 CDI84688.1 - 0.45 10.3 8.4 0.82 9.4 5.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) Activator_LAG-3 PF11498.3 CDI84688.1 - 3.2 6.3 25.2 0.053 12.2 12.4 1.8 2 0 0 2 2 2 0 Transcriptional activator LAG-3 Suf PF05843.9 CDI84690.1 - 0.002 17.9 2.3 0.002 17.9 1.6 14.1 5 2 5 12 12 12 2 Suppressor of forked protein (Suf) PAT1 PF09770.4 CDI84691.1 - 0.0019 16.5 83.1 0.0024 16.2 57.6 1.2 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 Med15 PF09606.5 CDI84691.1 - 0.036 12.2 113.9 0.045 11.9 79.0 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Utp14 PF04615.8 CDI84691.1 - 0.21 9.6 57.4 0.3 9.2 39.8 1.2 1 0 0 1 1 1 0 Utp14 protein Parvo_coat PF00740.13 CDI84691.1 - 9.1 5.0 42.8 11 4.8 29.7 1.2 1 0 0 1 1 1 0 Parvovirus coat protein VP2 Med15 PF09606.5 CDI84692.1 - 1.2e-05 23.7 45.6 1.3e-05 23.6 31.6 1.0 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal PAT1 PF09770.4 CDI84692.1 - 0.00075 17.8 33.6 0.00075 17.8 23.3 1.0 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 SARG PF15385.1 CDI84692.1 - 0.021 14.1 19.3 0.024 14.0 13.4 1.1 1 0 0 1 1 1 0 Specifically androgen-regulated gene protein FLO_LFY PF01698.11 CDI84692.1 - 0.081 11.7 10.0 0.1 11.4 6.9 1.2 1 0 0 1 1 1 0 Floricaula / Leafy protein Hid1 PF12722.2 CDI84692.1 - 0.24 9.0 11.8 0.23 9.1 8.2 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Herpes_UL87 PF03043.9 CDI84692.1 - 0.3 9.4 4.8 0.3 9.4 3.3 1.1 1 0 0 1 1 1 0 Herpesvirus UL87 family eIF-3_zeta PF05091.7 CDI84692.1 - 0.3 9.6 16.5 0.35 9.4 11.4 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) AAA_23 PF13476.1 CDI84692.1 - 0.41 10.9 10.0 0.6 10.3 6.9 1.3 1 0 0 1 1 1 0 AAA domain MSP1_C PF07462.6 CDI84692.1 - 0.68 8.2 5.6 0.66 8.2 3.9 1.1 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus RR_TM4-6 PF06459.7 CDI84692.1 - 0.81 9.5 14.1 1 9.1 9.8 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 HemX PF04375.9 CDI84692.1 - 0.86 8.1 28.3 1.1 7.7 19.6 1.1 1 0 0 1 1 1 0 HemX U1snRNP70_N PF12220.3 CDI84692.1 - 1 9.7 25.5 0.17 12.2 5.2 2.1 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal CDC45 PF02724.9 CDI84692.1 - 1.1 7.2 11.8 1.4 6.8 8.2 1.2 1 0 0 1 1 1 0 CDC45-like protein Neur_chan_memb PF02932.11 CDI84692.1 - 1.1 9.1 8.9 1.3 8.8 6.2 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Rtf2 PF04641.7 CDI84692.1 - 1.1 8.4 11.3 1.2 8.2 7.8 1.3 1 0 0 1 1 1 0 Rtf2 RING-finger DUF4045 PF13254.1 CDI84692.1 - 1.6 7.9 16.1 2 7.6 11.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) SAGA-Tad1 PF12767.2 CDI84692.1 - 1.8 8.1 20.2 2.4 7.7 14.0 1.1 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit DUF605 PF04652.11 CDI84692.1 - 3.8 6.7 26.9 4.7 6.5 18.6 1.1 1 0 0 1 1 1 0 Vta1 like DUF1675 PF07897.6 CDI84692.1 - 4.5 7.0 17.1 5.1 6.8 11.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) FAM60A PF15396.1 CDI84692.1 - 6.9 6.3 14.9 9 5.9 10.3 1.1 1 0 0 1 1 1 0 Protein Family FAM60A FYDLN_acid PF09538.5 CDI84693.1 - 6.5 7.3 14.6 7.3 7.2 10.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) Rtf2 PF04641.7 CDI84694.1 - 0.00024 20.4 0.9 0.00031 20.0 0.6 1.2 1 0 0 1 1 1 1 Rtf2 RING-finger DUF3357 PF11837.3 CDI84694.1 - 0.00092 19.0 6.2 0.023 14.5 1.1 2.3 1 1 1 2 2 2 2 Domain of unknown function (DUF3357) EOS1 PF12326.3 CDI84694.1 - 0.0017 17.9 4.4 0.085 12.4 0.5 2.2 1 1 1 2 2 2 1 N-glycosylation protein Glyco_transf_22 PF03901.12 CDI84694.1 - 0.0018 17.3 0.9 0.025 13.5 0.6 1.9 1 1 1 2 2 2 1 Alg9-like mannosyltransferase family DUF3899 PF13038.1 CDI84694.1 - 0.0018 18.4 2.5 0.2 11.8 0.2 2.4 2 1 0 2 2 2 1 Domain of unknown function (DUF3899) UPF0233 PF06781.7 CDI84694.1 - 0.002 17.7 0.9 0.5 10.0 0.0 2.2 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0233) EcsB PF05975.7 CDI84694.1 - 0.002 16.6 3.6 0.0024 16.3 2.5 1.1 1 0 0 1 1 1 1 Bacterial ABC transporter protein EcsB BatD PF13584.1 CDI84694.1 - 0.0025 16.4 6.0 0.0033 16.1 4.2 1.1 1 0 0 1 1 1 1 Oxygen tolerance DUF3530 PF12048.3 CDI84694.1 - 0.0026 16.8 21.5 0.021 13.8 2.1 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF3530) DUF2309 PF10070.4 CDI84694.1 - 0.0028 15.8 3.2 0.0032 15.6 2.2 1.0 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2309) Peroxin-13_N PF04088.8 CDI84694.1 - 0.0028 17.6 2.2 0.34 10.8 0.2 2.1 2 0 0 2 2 2 1 Peroxin 13, N-terminal region eIF-3_zeta PF05091.7 CDI84694.1 - 0.0029 16.2 8.0 0.0038 15.9 5.5 1.1 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DDHD PF02862.12 CDI84694.1 - 0.0038 17.0 3.9 0.0054 16.5 2.7 1.1 1 0 0 1 1 1 1 DDHD domain DUF2956 PF11169.3 CDI84694.1 - 0.0074 16.2 3.1 0.0074 16.2 2.2 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2956) 7tm_1 PF00001.16 CDI84694.1 - 0.0075 15.4 10.5 0.12 11.4 7.3 2.0 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Peptidase_S49_N PF08496.5 CDI84694.1 - 0.0083 15.9 7.2 0.19 11.5 0.9 2.1 2 0 0 2 2 2 1 Peptidase family S49 N-terminal DUF1510 PF07423.6 CDI84694.1 - 0.0087 15.4 6.6 0.42 9.9 2.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1510) G-alpha PF00503.15 CDI84694.1 - 0.011 14.4 4.6 0.014 14.1 3.2 1.1 1 0 0 1 1 1 0 G-protein alpha subunit DUF1345 PF07077.6 CDI84694.1 - 0.012 15.1 1.5 2.7 7.4 0.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1345) PSK PF06404.7 CDI84694.1 - 0.014 16.1 6.0 0.54 11.0 1.4 2.2 2 0 0 2 2 2 0 Phytosulfokine precursor protein (PSK) FHIPEP PF00771.15 CDI84694.1 - 0.015 13.6 13.5 0.013 13.9 1.5 2.0 1 1 1 2 2 2 0 FHIPEP family Peptidase_C12 PF01088.16 CDI84694.1 - 0.016 14.3 8.4 0.067 12.3 0.1 2.1 2 0 0 2 2 2 0 Ubiquitin carboxyl-terminal hydrolase, family 1 Herpes_DNAp_acc PF04929.7 CDI84694.1 - 0.016 14.1 5.7 0.022 13.7 3.9 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Neur_chan_memb PF02932.11 CDI84694.1 - 0.017 15.0 2.7 0.022 14.6 1.9 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF912 PF06024.7 CDI84694.1 - 0.02 14.9 2.7 0.02 14.9 1.9 2.2 1 1 1 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) PRA1 PF03208.14 CDI84694.1 - 0.021 14.1 0.8 0.084 12.2 0.4 1.8 1 1 1 2 2 2 0 PRA1 family protein DUF2782 PF11191.3 CDI84694.1 - 0.026 14.5 7.7 0.76 9.7 2.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2782) ExbD PF02472.11 CDI84694.1 - 0.027 14.4 7.5 0.032 14.2 5.2 1.1 1 0 0 1 1 1 0 Biopolymer transport protein ExbD/TolR Auxin_inducible PF02519.9 CDI84694.1 - 0.029 14.4 2.8 0.67 10.0 0.1 2.1 2 0 0 2 2 2 0 Auxin responsive protein Pex14_N PF04695.8 CDI84694.1 - 0.029 14.4 22.8 0.095 12.7 6.0 2.1 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Ripply PF14998.1 CDI84694.1 - 0.03 14.4 9.7 0.44 10.6 0.5 2.1 2 0 0 2 2 2 0 Transcription Regulator Dala_Dala_lig_N PF01820.16 CDI84694.1 - 0.031 14.5 2.4 2.1 8.6 0.4 2.1 2 0 0 2 2 2 0 D-ala D-ala ligase N-terminus Gemini_mov PF01708.11 CDI84694.1 - 0.034 13.6 6.2 0.084 12.4 4.3 1.6 1 1 0 1 1 1 0 Geminivirus putative movement protein Apc15p PF05841.6 CDI84694.1 - 0.04 14.6 11.2 1.3 9.7 3.3 2.1 2 0 0 2 2 2 0 Apc15p protein NADHdeh_related PF10125.4 CDI84694.1 - 0.041 13.0 0.3 0.24 10.5 0.0 1.9 1 1 1 2 2 2 0 NADH dehydrogenase I, subunit N related protein DUF2298 PF10060.4 CDI84694.1 - 0.042 12.6 0.0 0.048 12.5 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized membrane protein (DUF2298) GRP PF07172.6 CDI84694.1 - 0.043 14.2 2.8 1.1 9.8 0.7 2.1 2 0 0 2 2 2 0 Glycine rich protein family Nha1_C PF08619.5 CDI84694.1 - 0.05 12.8 4.3 0.066 12.4 3.0 1.1 1 0 0 1 1 1 0 Alkali metal cation/H+ antiporter Nha1 C terminus GPCR_chapero_1 PF11904.3 CDI84694.1 - 0.052 12.6 3.9 0.067 12.3 2.7 1.2 1 0 0 1 1 1 0 GPCR-chaperone Herpes_UL87 PF03043.9 CDI84694.1 - 0.062 11.6 3.9 0.076 11.3 2.7 1.2 1 0 0 1 1 1 0 Herpesvirus UL87 family CD34_antigen PF06365.7 CDI84694.1 - 0.063 12.9 6.9 0.24 11.0 0.5 2.1 1 1 1 2 2 2 0 CD34/Podocalyxin family PIG-U PF06728.8 CDI84694.1 - 0.066 12.0 9.3 0.81 8.4 6.5 2.0 1 1 0 1 1 1 0 GPI transamidase subunit PIG-U DUF3853 PF12964.2 CDI84694.1 - 0.067 12.9 6.6 1.4 8.7 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3853) Erv26 PF04148.8 CDI84694.1 - 0.07 12.4 2.7 0.096 12.0 1.8 1.2 1 0 0 1 1 1 0 Transmembrane adaptor Erv26 DUF1628 PF07790.6 CDI84694.1 - 0.071 13.8 0.8 0.58 10.9 0.0 2.1 2 0 0 2 2 1 0 Protein of unknown function (DUF1628) DUF819 PF05684.7 CDI84694.1 - 0.072 11.8 0.9 0.1 11.3 0.3 1.4 1 1 1 2 2 2 0 Protein of unknown function (DUF819) CD99L2 PF12301.3 CDI84694.1 - 0.095 12.3 2.3 0.19 11.4 1.6 1.4 1 1 0 1 1 1 0 CD99 antigen like protein 2 DUF2370 PF10176.4 CDI84694.1 - 0.1 11.9 5.6 0.3 10.3 0.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2370) Tmemb_185A PF10269.4 CDI84694.1 - 0.11 12.0 11.2 0.038 13.5 2.7 2.1 1 1 1 2 2 2 0 Transmembrane Fragile-X-F protein TatC PF00902.13 CDI84694.1 - 0.12 11.8 1.9 0.084 12.2 0.5 1.5 1 1 0 1 1 1 0 Sec-independent protein translocase protein (TatC) OSTbeta PF15048.1 CDI84694.1 - 0.12 12.5 6.4 2.5 8.1 1.9 2.1 2 0 0 2 2 2 0 Organic solute transporter subunit beta protein 60KD_IMP PF02096.15 CDI84694.1 - 0.16 11.5 23.1 0.31 10.6 3.6 2.2 1 1 1 2 2 2 0 60Kd inner membrane protein RskA PF10099.4 CDI84694.1 - 0.16 11.6 14.1 1.2 8.8 3.6 2.0 1 1 1 2 2 2 0 Anti-sigma-K factor rskA DHHW PF14286.1 CDI84694.1 - 0.18 11.0 3.1 0.28 10.4 2.2 1.2 1 0 0 1 1 1 0 DHHW protein TRC8_N PF13705.1 CDI84694.1 - 0.19 10.2 4.9 0.21 10.0 3.4 1.1 1 0 0 1 1 1 0 TRC8 N-terminal domain Sex_peptide PF08138.6 CDI84694.1 - 0.27 11.0 1.6 3.8 7.4 0.3 2.3 2 0 0 2 2 2 0 Sex peptide (SP) family Cad PF03596.8 CDI84694.1 - 0.28 10.8 1.3 0.49 10.0 0.9 1.5 1 1 0 1 1 1 0 Cadmium resistance transporter EIIBC-GUT_N PF03612.9 CDI84694.1 - 0.35 10.4 8.9 1.1 8.8 1.5 2.0 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus LMBR1 PF04791.11 CDI84694.1 - 0.38 9.2 8.4 0.67 8.4 5.7 1.5 1 1 0 1 1 1 0 LMBR1-like membrane protein ATAD4 PF15321.1 CDI84694.1 - 0.43 11.6 12.3 3.2 8.8 3.1 2.1 2 0 0 2 2 2 0 ATPase family AAA domain containing 4 DUF3371 PF11851.3 CDI84694.1 - 0.52 10.9 27.9 2.2 8.9 5.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3371) Trep_Strep PF09605.5 CDI84694.1 - 0.55 9.8 3.1 3 7.4 0.2 2.0 1 1 1 2 2 2 0 Hypothetical bacterial integral membrane protein (Trep_Strep) Topoisom_I_N PF02919.10 CDI84694.1 - 0.56 9.4 6.5 4 6.6 0.0 2.0 2 0 0 2 2 2 0 Eukaryotic DNA topoisomerase I, DNA binding fragment 5_nucleotid PF05761.9 CDI84694.1 - 0.57 8.6 6.1 0.68 8.3 4.2 1.1 1 0 0 1 1 1 0 5' nucleotidase family DUF2852 PF11014.3 CDI84694.1 - 0.59 10.1 6.0 1.5 8.8 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2852) DUF2269 PF10027.4 CDI84694.1 - 0.6 9.8 8.8 3 7.6 0.4 2.1 1 1 1 2 2 2 0 Predicted integral membrane protein (DUF2269) PigN PF04987.9 CDI84694.1 - 0.7 8.4 18.1 0.047 12.3 4.5 2.0 1 1 1 2 2 2 0 Phosphatidylinositolglycan class N (PIG-N) TMEM51 PF15345.1 CDI84694.1 - 0.76 9.4 23.2 2.1 7.9 7.4 2.0 2 0 0 2 2 2 0 Transmembrane protein 51 Fes1 PF08609.5 CDI84694.1 - 0.79 10.2 5.6 8.7 6.9 0.9 2.1 2 0 0 2 2 2 0 Nucleotide exchange factor Fes1 GWT1 PF06423.7 CDI84694.1 - 0.83 9.7 4.5 0.68 10.0 0.2 2.1 1 1 1 2 2 2 0 GWT1 TMEM223 PF14640.1 CDI84694.1 - 0.87 9.5 12.9 0.2 11.5 1.9 2.0 1 1 1 2 2 2 0 Transmembrane protein 223 DivIC PF04977.10 CDI84694.1 - 0.98 8.9 34.9 0.29 10.6 4.6 2.2 2 0 0 2 2 2 0 Septum formation initiator PCYCGC PF13798.1 CDI84694.1 - 1.1 8.9 9.7 1.2 8.8 1.1 2.1 2 0 0 2 2 2 0 Protein of unknown function with PCYCGC motif CIAPIN1 PF05093.8 CDI84694.1 - 1.2 9.2 12.1 0.93 9.6 0.7 2.2 2 0 0 2 2 2 0 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis DnaJ-X PF14308.1 CDI84694.1 - 1.2 8.3 12.5 1.3 8.2 2.7 2.0 2 0 0 2 2 2 0 X-domain of DnaJ-containing TOM13 PF08219.6 CDI84694.1 - 1.4 8.7 7.0 8.7 6.1 0.2 2.2 2 0 0 2 2 2 0 Outer membrane protein TOM13 Endonuc_Holl PF10107.4 CDI84694.1 - 1.5 8.5 11.5 2.4 7.8 2.8 2.0 2 0 0 2 2 2 0 Endonuclease related to archaeal Holliday junction resolvase SPX PF03105.14 CDI84694.1 - 1.6 8.4 10.5 2.5 7.7 7.3 1.3 1 1 0 1 1 1 0 SPX domain DUF3512 PF12024.3 CDI84694.1 - 1.6 7.9 8.5 2.1 7.5 1.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3512) DUF3169 PF11368.3 CDI84694.1 - 1.7 7.7 5.2 0.78 8.8 0.6 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3169) EphA2_TM PF14575.1 CDI84694.1 - 1.7 9.0 18.8 4 7.9 3.8 2.4 1 1 1 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Rrp15p PF07890.7 CDI84694.1 - 1.9 8.5 14.9 0.59 10.1 2.3 2.1 2 0 0 2 2 2 0 Rrp15p SAGA-Tad1 PF12767.2 CDI84694.1 - 2 8.0 19.5 2 8.0 4.3 2.0 2 0 0 2 2 2 0 Transcriptional regulator of RNA polII, SAGA, subunit SDF PF00375.13 CDI84694.1 - 2 7.0 4.2 8.2 5.0 0.0 2.0 1 1 1 2 2 2 0 Sodium:dicarboxylate symporter family DUF3278 PF11683.3 CDI84694.1 - 2 8.4 4.6 11 6.0 0.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3278) DUF2722 PF10846.3 CDI84694.1 - 2.3 7.1 28.7 0.25 10.3 4.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) DUF3408 PF11888.3 CDI84694.1 - 2.3 8.1 10.8 5.6 6.8 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3408) Hep_59 PF07052.6 CDI84694.1 - 2.4 8.5 15.9 2.5 8.5 0.6 2.1 2 0 0 2 2 2 0 Hepatocellular carcinoma-associated antigen 59 WASH-7_C PF14746.1 CDI84694.1 - 2.7 7.5 16.2 0.22 11.1 2.5 2.1 2 0 0 2 2 2 0 WASH complex subunit 7, C-terminal Neurensin PF14927.1 CDI84694.1 - 2.8 7.3 9.5 4 6.8 1.2 2.4 1 1 1 2 2 2 0 Neurensin FAM176 PF14851.1 CDI84694.1 - 3.1 7.4 14.7 0.31 10.7 0.9 2.1 1 1 1 2 2 2 0 FAM176 family PH_4 PF15404.1 CDI84694.1 - 3.2 7.2 12.7 6.1 6.3 3.4 2.1 2 0 0 2 2 2 0 Pleckstrin homology domain DUF4557 PF15101.1 CDI84694.1 - 3.4 7.4 30.9 0.29 10.9 7.9 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4557) Gastrin PF00918.12 CDI84694.1 - 3.4 8.5 17.5 1.4 9.7 1.0 2.2 2 0 0 2 2 2 0 Gastrin/cholecystokinin family DUF4064 PF13273.1 CDI84694.1 - 3.6 7.7 10.2 0.56 10.3 1.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF4064) DUF1517 PF07466.6 CDI84694.1 - 4.8 6.0 10.5 1.8 7.4 1.7 2.0 1 1 0 2 2 2 0 Protein of unknown function (DUF1517) DUF979 PF06166.7 CDI84694.1 - 4.8 6.0 6.2 1.4 7.8 0.5 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF979) NapE PF06796.6 CDI84694.1 - 5.5 6.3 8.5 14 5.0 2.2 2.9 2 1 0 2 2 2 0 Periplasmic nitrate reductase protein NapE DUF2227 PF09988.4 CDI84694.1 - 5.5 6.5 9.5 7.1 6.2 0.2 2.0 1 1 1 2 2 2 0 Uncharacterized metal-binding protein (DUF2227) Pap_E4 PF02711.9 CDI84694.1 - 5.6 7.8 13.1 9.2 7.1 3.5 2.1 2 0 0 2 2 2 0 E4 protein DUF4131 PF13567.1 CDI84694.1 - 6.3 6.1 17.0 0.64 9.3 3.3 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) HD-ZIP_N PF04618.7 CDI84694.1 - 6.5 7.3 7.9 10 6.7 0.3 2.1 2 0 0 2 2 2 0 HD-ZIP protein N terminus DUF2985 PF11204.3 CDI84694.1 - 6.6 6.5 10.5 5.5 6.8 3.0 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2985) Jiraiya PF15038.1 CDI84694.1 - 7.5 5.9 18.2 1.4e+02 1.7 12.6 2.3 1 1 0 1 1 1 0 Jiraiya Glyco_transf_15 PF01793.11 CDI84694.1 - 7.6 5.3 11.4 3.9 6.3 2.3 2.0 2 0 0 2 2 2 0 Glycolipid 2-alpha-mannosyltransferase Mak10 PF04112.8 CDI84694.1 - 7.8 5.6 8.6 8.6 5.5 0.9 2.0 2 0 0 2 2 2 0 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase DUF868 PF05910.7 CDI84694.1 - 7.8 5.8 7.4 14 5.0 0.5 2.0 2 0 0 2 2 2 0 Plant protein of unknown function (DUF868) Trp_oprn_chp PF09534.5 CDI84694.1 - 8.6 5.9 5.8 39 3.7 4.2 1.8 1 1 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) RR_TM4-6 PF06459.7 CDI84694.1 - 8.6 6.1 14.9 0.74 9.6 2.1 2.2 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Frizzled PF01534.12 CDI84694.1 - 8.7 5.0 11.5 0.074 11.8 0.6 2.0 1 1 1 2 2 2 0 Frizzled/Smoothened family membrane region Cytochrom_C_asm PF01578.15 CDI84694.1 - 8.7 5.8 10.0 1.7e+02 1.6 6.9 2.0 1 1 0 1 1 1 0 Cytochrome C assembly protein TMEM154 PF15102.1 CDI84694.1 - 8.8 6.0 21.7 0.43 10.2 4.0 2.1 1 1 1 2 2 2 0 TMEM154 protein family RNA_pol_Rbc25 PF08292.7 CDI84694.1 - 9.6 6.4 11.6 14 5.8 0.5 2.2 2 0 0 2 2 2 0 RNA polymerase III subunit Rpc25 Trypan_glycop_C PF10659.4 CDI84694.1 - 9.9 6.5 14.0 4.8 7.5 1.8 2.2 2 0 0 2 2 2 0 Trypanosome variant surface glycoprotein C-terminal domain RskA PF10099.4 CDI84695.1 - 0.00031 20.5 3.4 0.13 11.9 3.1 2.1 2 0 0 2 2 2 2 Anti-sigma-K factor rskA EphA2_TM PF14575.1 CDI84695.1 - 7.7 6.9 12.0 1.8 9.0 0.1 3.6 1 1 1 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain TMEM51 PF15345.1 CDI84695.1 - 7.9 6.0 31.3 0.031 13.9 3.2 2.0 1 1 1 2 2 2 0 Transmembrane protein 51 SR-25 PF10500.4 CDI84696.1 - 0.013 15.0 0.9 0.013 15.0 0.6 4.8 4 1 1 5 5 5 0 Nuclear RNA-splicing-associated protein SprA-related PF12118.3 CDI84697.1 - 0.00045 19.6 36.4 0.00045 19.6 25.2 11.2 7 4 4 11 11 11 1 SprA-related family Pox_Ag35 PF03286.9 CDI84697.1 - 0.0036 16.8 0.7 0.0036 16.8 0.5 5.8 5 0 0 5 5 5 2 Pox virus Ag35 surface protein PBP1_TM PF14812.1 CDI84698.1 - 0.24 11.7 1.5 0.62 10.4 0.2 2.1 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF1925 PF09094.6 CDI84698.1 - 0.99 9.4 5.9 0.32 10.9 0.8 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF1925) CDC45 PF02724.9 CDI84698.1 - 4.4 5.2 24.4 0.59 8.0 8.9 2.2 2 0 0 2 2 2 0 CDC45-like protein 7TM_GPCR_Srx PF10328.4 CDI84698.1 - 4.6 6.2 8.6 10 5.1 6.0 1.6 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srx Raftlin PF15250.1 CDI84698.1 - 8.3 4.8 27.1 0.5 8.8 9.1 2.3 2 0 0 2 2 2 0 Raftlin Fes1 PF08609.5 CDI84699.1 - 0.017 15.5 2.0 0.035 14.5 1.5 1.4 1 1 0 1 1 1 0 Nucleotide exchange factor Fes1 RIC3 PF15361.1 CDI84699.1 - 0.029 14.5 4.7 0.042 14.0 3.3 1.2 1 0 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 DUF3530 PF12048.3 CDI84699.1 - 0.043 12.8 7.3 0.071 12.0 5.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3530) CCDC84 PF14968.1 CDI84699.1 - 0.058 12.9 0.7 0.077 12.4 0.5 1.2 1 0 0 1 1 1 0 Coiled coil protein 84 DUF3357 PF11837.3 CDI84699.1 - 0.19 11.6 0.1 0.19 11.6 0.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF3357) APC_CDC26 PF10471.4 CDI84699.1 - 0.43 11.3 14.6 2.1 9.1 3.1 2.1 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit 1 Conotoxin PF02950.12 CDI84699.1 - 0.61 10.9 3.4 2.3 9.0 0.1 2.1 2 0 0 2 2 2 0 Conotoxin SIT PF15330.1 CDI84699.1 - 1.8 8.7 7.4 3 8.0 5.1 1.4 1 1 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT Med3 PF11593.3 CDI84699.1 - 2.8 7.0 21.7 0.36 10.0 1.2 2.0 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal PAT1 PF09770.4 CDI84699.1 - 4.2 5.4 23.7 4.7 5.3 16.4 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 PulG PF11773.3 CDI84699.1 - 8.2 6.2 10.6 9.4 6.0 0.9 2.1 2 0 0 2 2 2 0 Type II secretory pathway pseudopilin PAT1 PF09770.4 CDI84701.1 - 9.2e-05 20.8 89.7 9.2e-05 20.8 62.2 8.5 4 2 4 9 9 9 1 Topoisomerase II-associated protein PAT1 AAA_11 PF13086.1 CDI84703.1 - 0.63 9.5 0.0 0.63 9.5 0.0 4.8 3 1 1 4 4 4 0 AAA domain PAT1 PF09770.4 CDI84707.1 - 0.019 13.2 37.4 0.14 10.3 12.6 2.1 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 Spt20 PF12090.3 CDI84707.1 - 0.032 13.5 8.6 0.44 9.8 0.0 2.3 2 0 0 2 2 2 0 Spt20 family Suf PF05843.9 CDI84707.1 - 0.068 12.8 14.9 0.38 10.4 1.2 2.2 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) AAA_23 PF13476.1 CDI84707.1 - 0.96 9.7 8.9 2.4 8.4 1.2 2.2 2 0 0 2 2 2 0 AAA domain OmpH PF03938.9 CDI84707.1 - 1.4 8.8 28.9 3.9 7.4 8.6 2.8 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Med15 PF09606.5 CDI84707.1 - 1.8 6.6 64.6 0.018 13.2 11.5 3.0 3 0 0 3 3 3 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF2201_N PF13203.1 CDI84707.1 - 3.3 6.7 23.8 0.24 10.5 4.1 2.3 2 0 0 2 2 2 0 Putative metallopeptidase domain TFIIA PF03153.8 CDI84707.1 - 6.9 6.4 29.6 1.5 8.6 6.8 2.3 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Ribosomal_60s PF00428.14 CDI84708.1 - 0.022 15.1 34.7 0.022 15.1 24.0 10.7 1 1 7 8 8 8 0 60s Acidic ribosomal protein DAGK_acc PF00609.14 CDI84710.1 - 6.3e-27 94.6 0.0 1e-26 94.0 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase accessory domain DAGK_cat PF00781.19 CDI84710.1 - 2.9e-16 59.0 2.3 5.5e-16 58.1 0.0 2.5 2 1 0 2 2 2 1 Diacylglycerol kinase catalytic domain Ycf4 PF02392.11 CDI84710.1 - 0.14 11.4 0.1 0.23 10.7 0.0 1.3 1 0 0 1 1 1 0 Ycf4 Pkinase_Tyr PF07714.12 CDI84711.1 - 3.6e-51 173.7 0.0 1e-48 165.6 0.0 3.4 2 1 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.20 CDI84711.1 - 4.1e-50 170.3 0.1 4.7e-47 160.3 0.0 3.2 3 0 0 3 3 3 2 Protein kinase domain MORN PF02493.15 CDI84711.1 - 6.3e-07 28.7 20.1 0.00052 19.5 1.1 4.3 4 0 0 4 4 4 2 MORN repeat SAM_1 PF00536.25 CDI84711.1 - 0.00084 19.4 0.3 0.002 18.2 0.2 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) DUF4149 PF13664.1 CDI84712.1 - 9.5e-08 32.0 2.0 5.9e-07 29.4 0.3 3.0 3 1 0 3 3 3 1 Domain of unknown function (DUF4149) Kelch_3 PF13415.1 CDI84714.1 - 4.5e-24 84.0 2.1 3.3e-06 27.1 0.0 5.3 5 1 0 5 5 5 3 Galactose oxidase, central domain Kelch_4 PF13418.1 CDI84714.1 - 7.6e-18 64.0 2.0 0.00042 20.0 0.0 4.9 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_6 PF13964.1 CDI84714.1 - 4.6e-12 45.5 0.2 0.015 15.4 0.0 5.4 6 0 0 6 6 6 3 Kelch motif Kelch_5 PF13854.1 CDI84714.1 - 2.6e-11 43.1 1.0 0.00013 21.7 0.0 4.3 4 0 0 4 4 4 3 Kelch motif Kelch_1 PF01344.20 CDI84714.1 - 3.5e-07 29.6 0.5 0.035 13.6 0.0 4.4 5 0 0 5 5 5 2 Kelch motif Kelch_2 PF07646.10 CDI84714.1 - 0.0076 15.9 5.2 20 5.1 1.2 4.7 6 1 0 6 6 6 0 Kelch motif RAG2 PF03089.9 CDI84714.1 - 0.0087 14.8 0.1 0.58 8.8 0.0 2.9 3 1 0 4 4 4 1 Recombination activating protein 2 TipAS PF07739.8 CDI84714.1 - 0.014 15.6 1.4 0.027 14.7 1.0 1.5 1 0 0 1 1 1 0 TipAS antibiotic-recognition domain PV-1 PF06637.6 CDI84714.1 - 0.092 11.2 4.7 0.14 10.7 3.2 1.2 1 0 0 1 1 1 0 PV-1 protein (PLVAP) Phyto_Pns9_10 PF05878.6 CDI84714.1 - 0.16 10.9 0.9 0.24 10.3 0.6 1.2 1 0 0 1 1 1 0 Phytoreovirus nonstructural protein Pns9/Pns10 Spectrin PF00435.16 CDI84714.1 - 0.36 11.1 4.8 4.2 7.6 0.1 2.3 1 1 1 2 2 2 0 Spectrin repeat ECM11 PF15463.1 CDI84714.1 - 0.45 10.7 6.2 0.061 13.6 1.5 1.6 2 0 0 2 2 2 0 Extracellular mutant protein 11 DUF4200 PF13863.1 CDI84714.1 - 0.89 9.5 7.0 1.5 8.7 4.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) Ribosomal_L6e PF01159.14 CDI84715.1 - 2.2e-35 121.1 1.7 3.5e-35 120.5 1.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L6e DED PF01335.16 CDI84716.1 - 3.3 7.8 9.3 1.7 8.8 0.5 3.0 3 0 0 3 3 3 0 Death effector domain BBS2_N PF14781.1 CDI84717.1 - 1.9 8.0 5.9 0.47 10.0 1.1 2.2 1 1 1 2 2 2 0 Ciliary BBSome complex subunit 2, N-terminal Acetyltransf_1 PF00583.19 CDI84718.1 - 4.8e-15 55.3 0.0 7e-15 54.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 CDI84718.1 - 1.3e-10 41.2 0.0 1.9e-10 40.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 CDI84718.1 - 8.3e-08 32.3 0.0 1.5e-07 31.5 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 CDI84718.1 - 1.9e-06 28.1 0.0 1.9e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 CDI84718.1 - 4.9e-06 26.4 0.0 9.6e-06 25.5 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 CDI84718.1 - 3.4e-05 23.6 0.1 7.7e-05 22.5 0.0 1.6 1 1 0 1 1 1 1 GCN5-related N-acetyl-transferase FR47 PF08445.5 CDI84718.1 - 0.00063 19.4 0.0 0.0011 18.6 0.0 1.4 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_4 PF13420.1 CDI84718.1 - 0.0013 18.7 0.0 0.0017 18.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 CDI84718.1 - 0.0042 16.9 0.0 0.0079 16.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain AMP-binding PF00501.23 CDI84719.1 - 5.3e-07 28.3 0.4 0.017 13.5 0.0 2.7 2 1 0 2 2 2 2 AMP-binding enzyme Pkinase PF00069.20 CDI84720.1 - 6.9e-37 126.9 0.1 1.6e-16 60.2 0.3 3.4 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CDI84720.1 - 3.8e-10 39.2 0.1 6.1e-05 22.2 0.0 2.9 3 0 0 3 3 3 2 Protein tyrosine kinase Neur_chan_memb PF02932.11 CDI84721.1 - 4.9e-06 26.5 3.9 8.2e-06 25.8 2.7 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region YfhO PF09586.5 CDI84721.1 - 0.00054 18.1 3.6 0.00054 18.1 2.5 2.0 2 0 0 2 2 2 1 Bacterial membrane protein YfhO Pex24p PF06398.6 CDI84721.1 - 0.007 15.2 6.4 0.022 13.5 4.5 1.8 1 1 0 1 1 1 1 Integral peroxisomal membrane peroxin DUF929 PF06053.6 CDI84721.1 - 0.014 14.5 0.8 0.37 9.8 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF929) DUF2244 PF10003.4 CDI84721.1 - 0.015 14.7 1.7 0.015 14.7 1.2 2.4 2 2 1 3 3 3 0 Integral membrane protein (DUF2244) PalH PF08733.5 CDI84721.1 - 0.019 13.8 0.2 0.019 13.8 0.1 2.1 1 1 0 2 2 2 0 PalH/RIM21 PRA1 PF03208.14 CDI84721.1 - 0.025 13.9 1.4 0.03 13.6 0.3 1.8 2 0 0 2 2 2 0 PRA1 family protein RskA PF10099.4 CDI84721.1 - 0.043 13.5 42.0 0.52 10.0 2.4 3.1 1 1 2 3 3 3 0 Anti-sigma-K factor rskA SpoIIIAH PF12685.2 CDI84721.1 - 0.066 12.6 15.0 0.43 10.0 10.4 2.3 1 1 0 1 1 1 0 SpoIIIAH-like protein UbiA PF01040.13 CDI84721.1 - 0.17 11.0 8.3 0.15 11.2 3.2 2.4 3 0 0 3 3 3 0 UbiA prenyltransferase family Herpes_LMP1 PF05297.6 CDI84721.1 - 0.19 10.6 3.4 0.31 9.9 2.4 1.3 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) Tetraspannin PF00335.15 CDI84721.1 - 0.27 10.5 7.2 0.35 10.1 0.4 2.3 2 0 0 2 2 2 0 Tetraspanin family Herpes_UL87 PF03043.9 CDI84721.1 - 0.27 9.5 3.0 0.32 9.3 2.1 1.2 1 0 0 1 1 1 0 Herpesvirus UL87 family DUF4446 PF14584.1 CDI84721.1 - 0.28 11.0 10.8 0.15 11.8 1.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) Pex14_N PF04695.8 CDI84721.1 - 0.56 10.2 36.7 0.05 13.6 12.0 2.2 1 1 1 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF572 PF04502.8 CDI84721.1 - 0.56 9.3 15.1 0.82 8.8 10.4 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) V_ATPase_I PF01496.14 CDI84721.1 - 0.67 7.7 11.1 0.038 11.8 0.9 2.1 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family FA_desaturase PF00487.19 CDI84721.1 - 0.9 8.9 13.1 0.5 9.7 5.2 2.6 1 1 0 2 2 2 0 Fatty acid desaturase DUF966 PF06136.8 CDI84721.1 - 1.1 8.5 14.2 1.5 8.2 9.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Herpes_DNAp_acc PF04929.7 CDI84721.1 - 1.6 7.5 11.9 2.5 6.9 8.2 1.3 1 0 0 1 1 1 0 Herpes DNA replication accessory factor MSP1_C PF07462.6 CDI84721.1 - 1.7 6.9 6.5 2.5 6.3 4.5 1.2 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus PIG-S PF10510.4 CDI84721.1 - 2 6.9 13.7 2.5 6.6 9.5 1.1 1 0 0 1 1 1 0 Phosphatidylinositol-glycan biosynthesis class S protein RR_TM4-6 PF06459.7 CDI84721.1 - 2.2 8.1 15.9 3.2 7.5 11.0 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF1510 PF07423.6 CDI84721.1 - 2.3 7.5 17.1 3.4e+03 -2.9 11.9 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1510) Shadoo PF14999.1 CDI84721.1 - 2.8 7.7 16.4 0.067 13.0 1.8 2.2 2 0 0 2 2 2 0 Shadow of prion protein, neuroprotective Pol_alpha_B_N PF08418.5 CDI84721.1 - 6.1 6.2 14.4 8.4 5.8 10.0 1.1 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal R_equi_Vir PF05526.6 CDI84721.1 - 8.5 5.9 11.9 13 5.3 6.5 2.1 2 0 0 2 2 2 0 Rhodococcus equi virulence-associated protein PAT1 PF09770.4 CDI84721.1 - 9.1 4.3 48.6 11 4.0 33.7 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF4603 PF15376.1 CDI84723.1 - 0.59 7.2 36.5 0.74 6.9 25.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) DUF966 PF06136.8 CDI84723.1 - 1.7 8.0 54.8 1.8 7.9 38.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Utp14 PF04615.8 CDI84723.1 - 3.5 5.6 67.8 5.4 5.0 47.0 1.2 1 0 0 1 1 1 0 Utp14 protein Otopetrin PF03189.8 CDI84724.1 - 0.00092 18.3 0.9 0.0014 17.7 0.6 1.2 1 0 0 1 1 1 1 Otopetrin Ribosomal_60s PF00428.14 CDI84724.1 - 0.028 14.8 7.0 0.028 14.8 4.9 2.9 3 0 0 3 3 3 0 60s Acidic ribosomal protein Sporozoite_P67 PF05642.6 CDI84724.1 - 0.17 9.7 8.2 0.17 9.7 5.7 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Ycf1 PF05758.7 CDI84724.1 - 1 7.0 14.6 1 6.9 10.1 1.1 1 0 0 1 1 1 0 Ycf1 DUF572 PF04502.8 CDI84724.1 - 1.1 8.3 21.8 1.6 7.8 15.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) PAT1 PF09770.4 CDI84724.1 - 2.9 6.0 42.8 3.7 5.6 29.7 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Macoilin PF09726.4 CDI84724.1 - 3.1 5.9 19.5 3.7 5.6 13.5 1.1 1 0 0 1 1 1 0 Transmembrane protein PLRV_ORF5 PF01690.12 CDI84724.1 - 4.9 6.1 19.5 6.3 5.8 13.5 1.2 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein PPP4R2 PF09184.6 CDI84724.1 - 6.6 6.1 14.7 11 5.4 10.2 1.3 1 0 0 1 1 1 0 PPP4R2 DUF4551 PF15087.1 CDI84724.1 - 8.4 4.6 21.2 10 4.3 14.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) PAT1 PF09770.4 CDI84726.1 - 0.1 10.8 144.3 0.18 10.0 100.0 1.4 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 UPF0564 PF10595.4 CDI84727.1 - 0.00042 19.3 11.3 0.00042 19.3 7.8 2.1 2 0 0 2 2 2 1 Uncharacterised protein family UPF0564 FAD_binding_9 PF08021.6 CDI84729.1 - 0.15 11.9 4.0 0.21 11.5 2.8 1.1 1 0 0 1 1 1 0 Siderophore-interacting FAD-binding domain Ofd1_CTDD PF10637.4 CDI84729.1 - 0.35 9.9 10.0 0.39 9.7 6.9 1.0 1 0 0 1 1 1 0 Oxoglutarate and iron-dependent oxygenase degradation C-term BTV_NS2 PF04514.7 CDI84729.1 - 0.39 9.5 11.9 0.41 9.4 8.3 1.0 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 DDRGK PF09756.4 CDI84729.1 - 0.82 9.0 17.3 0.94 8.8 12.0 1.1 1 0 0 1 1 1 0 DDRGK domain AUX_IAA PF02309.11 CDI84729.1 - 0.82 9.3 9.2 0.88 9.2 6.4 1.0 1 0 0 1 1 1 0 AUX/IAA family Pex14_N PF04695.8 CDI84729.1 - 1 9.3 15.3 1.2 9.1 10.6 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF702 PF05142.7 CDI84729.1 - 1.1 9.3 9.9 1.4 9.1 6.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF702) Band_3_cyto PF07565.8 CDI84729.1 - 2.1 7.8 13.8 2.1 7.7 9.6 1.0 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Lipase_GDSL_3 PF14606.1 CDI84729.1 - 2.2 8.0 8.7 2.6 7.7 6.0 1.1 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family DUF3698 PF12479.3 CDI84729.1 - 2.4 8.2 7.6 2.9 8.0 5.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3698) DUF3449 PF11931.3 CDI84729.1 - 2.4 7.6 15.3 2.6 7.4 10.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3449) Glyco_transf_15 PF01793.11 CDI84729.1 - 2.5 6.9 11.2 2.9 6.7 7.7 1.1 1 0 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase FAM60A PF15396.1 CDI84729.1 - 2.9 7.5 11.1 3.4 7.3 7.7 1.0 1 0 0 1 1 1 0 Protein Family FAM60A Mit_KHE1 PF10173.4 CDI84729.1 - 2.9 7.6 6.8 4 7.2 4.7 1.3 1 0 0 1 1 1 0 Mitochondrial K+-H+ exchange-related Gti1_Pac2 PF09729.4 CDI84729.1 - 3.8 7.3 8.9 4.2 7.2 6.2 1.2 1 0 0 1 1 1 0 Gti1/Pac2 family Lin-8 PF03353.10 CDI84729.1 - 4.2 6.5 16.9 4.7 6.4 11.7 1.0 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist DUF966 PF06136.8 CDI84729.1 - 4.3 6.6 12.4 5.2 6.3 8.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF966) FYDLN_acid PF09538.5 CDI84729.1 - 4.3 7.9 7.9 5.6 7.5 5.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) F-protein PF00469.15 CDI84729.1 - 4.4 6.6 11.5 4.4 6.6 7.9 1.1 1 0 0 1 1 1 0 Negative factor, (F-Protein) or Nef DUF2370 PF10176.4 CDI84729.1 - 4.5 6.5 7.6 5 6.3 5.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) eIF-3_zeta PF05091.7 CDI84729.1 - 5.3 5.5 16.3 5.4 5.5 11.3 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Dynamin_N PF00350.18 CDI84729.1 - 5.5 6.7 8.3 6.1 6.6 5.8 1.1 1 0 0 1 1 1 0 Dynamin family DUF2203 PF09969.4 CDI84729.1 - 6.8 6.9 10.0 9.3 6.4 6.9 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) DOR PF14839.1 CDI84729.1 - 7.1 6.3 17.9 7.3 6.2 12.4 1.1 1 0 0 1 1 1 0 DOR family SeqA PF03925.8 CDI84729.1 - 7.2 6.2 13.7 8.8 5.9 9.5 1.2 1 0 0 1 1 1 0 SeqA protein Kei1 PF08552.6 CDI84729.1 - 7.4 6.1 7.2 8.2 6.0 5.0 1.2 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 Asp-B-Hydro_N PF05279.6 CDI84729.1 - 7.6 6.3 11.0 8.6 6.1 7.6 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region DUF4045 PF13254.1 CDI84729.1 - 8 5.6 12.1 9 5.4 8.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Peptidase_S15 PF02129.13 CDI84729.1 - 8.2 5.7 10.7 9 5.6 7.4 1.0 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) DUF2265 PF10023.4 CDI84729.1 - 8.3 5.4 16.3 9.2 5.2 11.3 1.0 1 0 0 1 1 1 0 Predicted aminopeptidase (DUF2265) ARF7EP_C PF14949.1 CDI84729.1 - 8.3 6.8 12.0 11 6.5 8.3 1.3 1 0 0 1 1 1 0 ARF7 effector protein C-terminus Neur_chan_memb PF02932.11 CDI84729.1 - 8.4 6.1 9.4 9.5 6.0 6.5 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF4175 PF13779.1 CDI84729.1 - 8.6 3.9 37.3 9.5 3.7 25.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) EIIBC-GUT_N PF03612.9 CDI84729.1 - 8.7 5.9 9.7 12 5.5 6.7 1.3 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus FemAB PF02388.11 CDI84729.1 - 9.2 4.8 16.7 9.9 4.7 11.5 1.0 1 0 0 1 1 1 0 FemAB family Endonuc_Holl PF10107.4 CDI84729.1 - 9.9 5.8 18.2 11 5.6 12.6 1.1 1 0 0 1 1 1 0 Endonuclease related to archaeal Holliday junction resolvase PI3K_C2 PF00792.19 CDI84730.1 - 0.021 14.6 0.1 0.021 14.6 0.1 4.2 6 0 0 6 6 6 0 Phosphoinositide 3-kinase C2 SAPS PF04499.10 CDI84731.1 - 0.16 10.5 24.6 0.2 10.2 17.0 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF4045 PF13254.1 CDI84731.1 - 0.68 9.1 26.1 0.73 9.0 18.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) DUF1510 PF07423.6 CDI84731.1 - 8.3 5.7 32.2 10 5.4 22.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) IncA PF04156.9 CDI84732.1 - 1.4e-11 44.4 7.5 1.4e-11 44.4 5.2 3.6 2 1 0 2 2 2 2 IncA protein AUX_IAA PF02309.11 CDI84733.1 - 0.018 14.7 11.8 0.022 14.5 8.2 1.0 1 0 0 1 1 1 0 AUX/IAA family DUF4401 PF14351.1 CDI84733.1 - 0.023 13.7 0.3 0.028 13.4 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4401) Serinc PF03348.10 CDI84733.1 - 0.035 12.8 9.5 0.039 12.6 6.6 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) Zip PF02535.17 CDI84733.1 - 0.037 13.0 2.2 0.048 12.6 1.6 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Cas1_AcylT PF07779.7 CDI84733.1 - 0.16 10.4 5.6 0.18 10.2 3.9 1.1 1 0 0 1 1 1 0 10 TM Acyl Transferase domain found in Cas1p CKAP2_C PF15297.1 CDI84733.1 - 0.29 9.8 16.1 0.36 9.5 11.2 1.0 1 0 0 1 1 1 0 Cytoskeleton-associated protein 2 C-terminus Plasmodium_Vir PF05795.6 CDI84733.1 - 0.32 10.1 1.1 0.34 10.0 0.8 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein SID-1_RNA_chan PF13965.1 CDI84733.1 - 0.59 8.2 5.9 0.56 8.2 4.1 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DUF1632 PF07857.7 CDI84733.1 - 0.78 8.9 3.4 0.72 9.0 1.8 1.3 1 1 0 1 1 1 0 CEO family (DUF1632) HCO3_cotransp PF00955.16 CDI84733.1 - 1.1 7.7 4.0 1.3 7.6 2.7 1.2 1 0 0 1 1 1 0 HCO3- transporter family Neur_chan_memb PF02932.11 CDI84733.1 - 1.2 8.9 11.3 1.6 8.5 7.8 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF2828 PF11443.3 CDI84733.1 - 1.2 7.2 9.9 1.4 7.0 6.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Herpes_UL87 PF03043.9 CDI84733.1 - 1.2 7.3 9.0 1.3 7.3 6.3 1.0 1 0 0 1 1 1 0 Herpesvirus UL87 family FNIP_N PF14636.1 CDI84733.1 - 1.6 9.1 16.0 2.1 8.8 11.1 1.1 1 0 0 1 1 1 0 Folliculin-interacting protein N-terminus Kei1 PF08552.6 CDI84733.1 - 2 8.0 12.1 4 7.0 8.4 1.6 1 1 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 FLO_LFY PF01698.11 CDI84733.1 - 2.1 7.1 13.9 2.6 6.8 9.6 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein FAM60A PF15396.1 CDI84733.1 - 2.1 8.0 11.5 2.9 7.6 7.9 1.2 1 0 0 1 1 1 0 Protein Family FAM60A Hom_end_hint PF05203.11 CDI84733.1 - 2.2 7.9 11.3 2.6 7.6 7.9 1.1 1 0 0 1 1 1 0 Hom_end-associated Hint Senescence_reg PF04520.8 CDI84733.1 - 2.4 8.6 8.5 3.3 8.1 5.9 1.2 1 0 0 1 1 1 0 Senescence regulator Hid1 PF12722.2 CDI84733.1 - 2.9 5.4 19.0 3.6 5.1 13.2 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein 2OG-FeII_Oxy_5 PF13759.1 CDI84733.1 - 3.6 7.9 7.9 1.2 9.4 3.2 1.7 2 0 0 2 2 2 0 Putative 2OG-Fe(II) oxygenase Conotoxin PF02950.12 CDI84733.1 - 4.2 8.2 20.0 7.2 7.4 8.5 2.6 1 1 1 2 2 2 0 Conotoxin DHHW PF14286.1 CDI84733.1 - 4.7 6.4 9.7 5.8 6.1 6.7 1.2 1 0 0 1 1 1 0 DHHW protein Het-C PF07217.6 CDI84733.1 - 5.5 5.0 12.9 5.8 4.9 9.0 1.0 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C CDC37_N PF03234.9 CDI84733.1 - 6 7.1 18.0 7.7 6.7 12.5 1.1 1 0 0 1 1 1 0 Cdc37 N terminal kinase binding DUF912 PF06024.7 CDI84733.1 - 6.4 6.8 16.2 6 6.9 7.7 2.2 1 1 1 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Nha1_C PF08619.5 CDI84733.1 - 7.8 5.6 16.5 9.5 5.3 11.4 1.0 1 0 0 1 1 1 0 Alkali metal cation/H+ antiporter Nha1 C terminus DUF4228 PF14009.1 CDI84733.1 - 9.1 6.3 13.6 11 6.1 9.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4228) FimP PF09766.4 CDI84734.1 - 2.4 7.1 39.1 0.21 10.6 2.9 3.0 3 0 0 3 3 3 0 Fms-interacting protein DUF106 PF01956.11 CDI84734.1 - 7.8 5.9 13.7 4.8 6.6 5.1 2.3 2 0 0 2 2 2 0 Integral membrane protein DUF106 Med15 PF09606.5 CDI84735.1 - 0.12 10.5 16.3 0.15 10.2 11.3 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal MCPVI PF02993.9 CDI84735.1 - 2.8 8.0 7.7 3.3 7.7 5.4 1.0 1 0 0 1 1 1 0 Minor capsid protein VI Mem_trans PF03547.13 CDI84736.1 - 0.26 9.5 1.2 0.47 8.6 0.8 1.5 1 0 0 1 1 1 0 Membrane transport protein Ycf1 PF05758.7 CDI84736.1 - 0.75 7.4 9.5 0.96 7.0 6.6 1.2 1 0 0 1 1 1 0 Ycf1 FAM176 PF14851.1 CDI84736.1 - 4 7.0 7.5 8.9 5.9 5.2 1.6 1 0 0 1 1 1 0 FAM176 family Sec62 PF03839.11 CDI84736.1 - 6.1 6.1 10.8 9.6 5.5 7.5 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 DUF2215 PF10225.4 CDI84736.1 - 6.9 6.0 6.7 13 5.1 4.6 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) DUF4570 PF15134.1 CDI84737.1 - 0.0032 17.3 7.7 0.0052 16.6 5.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4570) DUF775 PF05603.7 CDI84737.1 - 0.0045 16.5 0.7 0.0045 16.5 0.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF775) Med15 PF09606.5 CDI84737.1 - 0.0068 14.6 16.4 0.0074 14.5 11.3 1.1 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal DUF808 PF05661.7 CDI84737.1 - 0.0076 15.1 0.7 0.0086 14.9 0.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF808) DUF853 PF05872.7 CDI84737.1 - 0.0078 14.6 3.2 0.0084 14.5 2.2 1.0 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF853) DUF4557 PF15101.1 CDI84737.1 - 0.008 16.0 3.7 0.0094 15.8 2.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4557) Pex14_N PF04695.8 CDI84737.1 - 0.012 15.6 4.1 0.015 15.3 2.8 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region VIT1 PF01988.14 CDI84737.1 - 0.014 14.9 8.7 0.027 13.9 6.0 1.4 1 1 0 1 1 1 0 VIT family Spt20 PF12090.3 CDI84737.1 - 0.031 13.6 0.8 0.035 13.4 0.6 1.1 1 0 0 1 1 1 0 Spt20 family DUF4496 PF14908.1 CDI84737.1 - 0.096 12.5 2.2 0.14 12.0 1.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4496) PAT1 PF09770.4 CDI84737.1 - 0.15 10.3 11.3 0.16 10.1 7.8 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF4199 PF13858.1 CDI84737.1 - 0.15 12.0 0.8 0.26 11.1 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) PHD_3 PF13922.1 CDI84737.1 - 0.63 10.3 9.5 0.43 10.8 4.9 2.0 2 0 0 2 2 2 0 PHD domain of transcriptional enhancer, Asx AAA_23 PF13476.1 CDI84737.1 - 0.73 10.1 5.5 0.87 9.8 3.8 1.1 1 0 0 1 1 1 0 AAA domain Suf PF05843.9 CDI84737.1 - 0.91 9.1 5.9 1.1 8.9 4.1 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) MscS_TM PF12794.2 CDI84737.1 - 2.4 6.7 6.9 3 6.3 4.8 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 Nitroreductase PF00881.19 CDI84737.1 - 5 6.9 10.3 6.6 6.5 7.2 1.2 1 0 0 1 1 1 0 Nitroreductase family DUF3373 PF11853.3 CDI84737.1 - 6 5.2 6.8 7.3 4.9 4.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) DUF3682 PF12446.3 CDI84737.1 - 8.4 6.6 16.1 5 7.4 9.9 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3682) Activator_LAG-3 PF11498.3 CDI84737.1 - 8.5 4.9 23.9 10 4.7 16.6 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 zf-DHHC PF01529.15 CDI84738.1 - 0.05 13.0 0.0 0.05 13.0 0.0 1.1 1 0 0 1 1 1 0 DHHC palmitoyltransferase Spt20 PF12090.3 CDI84738.1 - 0.13 11.5 9.1 0.19 11.0 6.3 1.3 1 0 0 1 1 1 0 Spt20 family PEX11 PF05648.9 CDI84738.1 - 0.45 9.7 9.1 0.62 9.3 6.3 1.1 1 0 0 1 1 1 0 Peroxisomal biogenesis factor 11 (PEX11) Peptidase_S15 PF02129.13 CDI84738.1 - 0.79 9.0 13.6 0.026 13.9 4.9 1.7 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) G0-G1_switch_2 PF15103.1 CDI84738.1 - 1.1 9.5 7.5 1.8 8.8 5.2 1.3 1 0 0 1 1 1 0 G0/G1 switch protein 2 DUF912 PF06024.7 CDI84738.1 - 1.3 9.1 4.6 2 8.5 3.2 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) PAT1 PF09770.4 CDI84738.1 - 1.5 6.9 30.5 2.2 6.4 21.2 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Suf PF05843.9 CDI84738.1 - 1.7 8.2 15.8 2.4 7.8 10.9 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Ctr PF04145.10 CDI84738.1 - 2.8 7.9 6.5 5.4 7.0 4.5 1.5 1 0 0 1 1 1 0 Ctr copper transporter family FYDLN_acid PF09538.5 CDI84738.1 - 2.9 8.4 5.4 6.6 7.3 0.9 2.4 2 1 0 2 2 2 0 Protein of unknown function (FYDLN_acid) Oleosin PF01277.12 CDI84738.1 - 3.1 7.3 5.4 6.4 6.3 3.7 1.4 1 0 0 1 1 1 0 Oleosin EIIBC-GUT_N PF03612.9 CDI84738.1 - 6.5 6.3 8.4 10 5.6 5.8 1.3 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus DUF1682 PF07946.9 CDI84739.1 - 0.26 10.1 4.9 0.4 9.4 3.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Not1 PF04054.10 CDI84741.1 - 0.43 9.3 12.5 0.53 9.0 8.7 1.2 1 0 0 1 1 1 0 CCR4-Not complex component, Not1 DUF1800 PF08811.6 CDI84741.1 - 1.1 8.1 32.8 1.3 7.8 22.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1800) DUF1788 PF08747.6 CDI84741.1 - 4.1 7.2 15.1 1.6 8.5 2.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1788) Glyco_hydro_3_C PF01915.17 CDI84741.1 - 5 6.5 11.2 6.2 6.2 7.8 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 3 C-terminal domain DUF668 PF05003.7 CDI84741.1 - 6.9 6.9 8.3 0.57 10.4 0.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF668) MIP-T3 PF10243.4 CDI84742.1 - 0.00022 19.8 97.3 0.00029 19.4 67.4 1.1 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 Daxx PF03344.10 CDI84742.1 - 2.6 6.4 71.4 3.2 6.1 49.5 1.1 1 0 0 1 1 1 0 Daxx Family PAT1 PF09770.4 CDI84743.1 - 0.0017 16.7 39.5 0.0017 16.7 27.4 1.7 2 0 0 2 2 2 1 Topoisomerase II-associated protein PAT1 Activator_LAG-3 PF11498.3 CDI84743.1 - 0.32 9.6 62.0 0.68 8.6 42.9 1.5 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Sporozoite_P67 PF05642.6 CDI84744.1 - 4.5e-05 21.5 5.1 5.3e-05 21.2 3.5 1.0 1 0 0 1 1 1 1 Sporozoite P67 surface antigen Med15 PF09606.5 CDI84744.1 - 0.002 16.4 8.7 0.002 16.4 6.0 1.6 2 0 0 2 2 2 1 ARC105 or Med15 subunit of Mediator complex non-fungal FliD_N PF02465.13 CDI84744.1 - 0.027 14.8 10.1 0.027 14.8 7.0 2.4 2 1 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus FHIPEP PF00771.15 CDI84744.1 - 0.14 10.4 8.3 0.2 9.9 5.8 1.2 1 0 0 1 1 1 0 FHIPEP family Activator_LAG-3 PF11498.3 CDI84744.1 - 0.63 8.7 19.4 1.3 7.7 13.4 1.5 1 0 0 1 1 1 0 Transcriptional activator LAG-3 BRF1 PF07741.8 CDI84744.1 - 1.2 9.4 9.2 2.8 8.2 0.4 2.3 2 0 0 2 2 2 0 Brf1-like TBP-binding domain IncA PF04156.9 CDI84744.1 - 1.8 8.1 26.9 4.1 6.9 18.7 1.6 1 1 0 1 1 1 0 IncA protein DUF912 PF06024.7 CDI84744.1 - 5.7 7.0 7.3 15 5.7 0.5 2.6 3 0 0 3 3 3 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Claudin_2 PF13903.1 CDI84744.1 - 6.6 6.3 15.8 1.2e+02 2.3 10.9 2.1 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction Nop14 PF04147.7 CDI84745.1 - 0.043 11.7 41.3 0.042 11.7 28.6 1.0 1 0 0 1 1 1 0 Nop14-like family CENP-T PF15511.1 CDI84745.1 - 0.65 9.1 26.7 0.66 9.1 18.5 1.0 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T CDC45 PF02724.9 CDI84745.1 - 0.9 7.4 34.5 0.94 7.4 23.9 1.0 1 0 0 1 1 1 0 CDC45-like protein Daxx PF03344.10 CDI84745.1 - 1 7.7 43.7 1.1 7.6 30.3 1.0 1 0 0 1 1 1 0 Daxx Family Zip PF02535.17 CDI84745.1 - 7.9 5.3 13.2 8.9 5.2 9.2 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter DUF2722 PF10846.3 CDI84745.1 - 8.7 5.2 15.8 11 4.9 11.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) SDA1 PF05285.7 CDI84745.1 - 8.8 5.5 41.9 9.2 5.4 29.1 1.0 1 0 0 1 1 1 0 SDA1 CD20 PF04103.10 CDI84746.1 - 0.0082 16.0 0.4 0.01 15.7 0.3 1.3 1 0 0 1 1 1 1 CD20-like family MRC1 PF09444.5 CDI84746.1 - 0.062 13.6 0.9 0.069 13.4 0.6 1.1 1 0 0 1 1 1 0 MRC1-like domain RAB3GAP2_N PF14655.1 CDI84746.1 - 0.19 10.6 6.0 0.22 10.4 4.1 1.1 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Activator_LAG-3 PF11498.3 CDI84746.1 - 0.39 9.4 35.7 0.43 9.2 24.8 1.0 1 0 0 1 1 1 0 Transcriptional activator LAG-3 AAA_23 PF13476.1 CDI84746.1 - 0.86 9.8 4.8 1 9.6 3.3 1.2 1 0 0 1 1 1 0 AAA domain RskA PF10099.4 CDI84746.1 - 0.98 9.1 15.5 2.1 8.0 10.8 1.5 1 1 0 1 1 1 0 Anti-sigma-K factor rskA Med15 PF09606.5 CDI84746.1 - 1.1 7.3 32.6 1.5 6.8 22.6 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF2586 PF10758.4 CDI84746.1 - 1.5 7.8 5.9 1.7 7.6 4.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2586) CoA_binding_2 PF13380.1 CDI84746.1 - 2.4 8.3 4.8 3.1 8.0 3.4 1.4 1 1 0 1 1 1 0 CoA binding domain Blt1 PF12754.2 CDI84746.1 - 5.7 6.4 9.0 6.7 6.2 6.2 1.1 1 0 0 1 1 1 0 Cell-cycle control medial ring component TFIIA PF03153.8 CDI84746.1 - 6.5 6.5 15.7 8.9 6.0 10.8 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit AF-4 PF05110.8 CDI84748.1 - 0.0037 15.2 16.0 0.0045 14.9 11.1 1.1 1 0 0 1 1 1 1 AF-4 proto-oncoprotein FAM222A PF15258.1 CDI84748.1 - 0.006 15.8 9.3 0.0062 15.8 6.4 1.0 1 0 0 1 1 1 1 Protein family of FAM222A LIN37 PF15306.1 CDI84748.1 - 0.013 15.4 1.4 0.013 15.4 1.0 1.6 1 1 1 2 2 2 0 LIN37 Med15 PF09606.5 CDI84748.1 - 0.023 12.9 15.5 0.023 12.9 10.7 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Trigger_C PF05698.9 CDI84748.1 - 0.024 14.4 4.7 0.029 14.2 3.2 1.2 1 0 0 1 1 1 0 Bacterial trigger factor protein (TF) C-terminus DUF3450 PF11932.3 CDI84748.1 - 0.043 13.0 11.2 0.051 12.8 7.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF3146 PF11344.3 CDI84748.1 - 0.049 13.0 0.2 0.1 12.0 0.0 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3146) BSP_II PF05432.6 CDI84748.1 - 0.054 12.7 0.8 0.078 12.2 0.6 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) TALPID3 PF15324.1 CDI84748.1 - 0.13 9.6 6.4 0.15 9.3 4.5 1.1 1 0 0 1 1 1 0 Hedgehog signalling target MRP-S31 PF15433.1 CDI84748.1 - 0.33 10.3 8.7 0.4 10.0 6.0 1.1 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 DUF3682 PF12446.3 CDI84748.1 - 0.38 11.0 19.3 0.5 10.6 13.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) BAT2_N PF07001.6 CDI84748.1 - 0.41 10.9 15.0 0.5 10.6 10.4 1.1 1 0 0 1 1 1 0 BAT2 N-terminus LIM_bind PF01803.11 CDI84748.1 - 0.44 9.6 9.5 0.32 10.0 5.9 1.3 1 1 0 1 1 1 0 LIM-domain binding protein Suf PF05843.9 CDI84748.1 - 0.57 9.8 9.8 0.67 9.6 6.8 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) CAF-1_p150 PF11600.3 CDI84748.1 - 0.96 8.7 11.1 1.4 8.2 7.7 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF3245 PF11595.3 CDI84748.1 - 2.6 8.3 12.4 2.3 8.4 0.7 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3245) Serinc PF03348.10 CDI84748.1 - 5.5 5.5 6.0 6.3 5.3 4.2 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) DUF2217 PF10265.4 CDI84748.1 - 8.1 5.0 9.2 9 4.9 6.4 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) APC_CDC26 PF10471.4 CDI84748.1 - 9 7.1 22.7 0.42 11.3 8.5 2.1 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit 1 Helicase_C PF00271.26 CDI84750.1 - 1.4e-27 95.3 0.0 1.4e-27 95.3 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 CDI84750.1 - 4.6e-10 39.2 0.0 1.5e-09 37.5 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase DUF1253 PF06862.7 CDI84750.1 - 0.0037 15.7 0.0 0.0037 15.7 0.0 2.1 3 0 0 3 3 3 1 Protein of unknown function (DUF1253) Activator_LAG-3 PF11498.3 CDI84750.1 - 4.2 6.0 19.5 6.1 5.4 13.5 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Utp14 PF04615.8 CDI84751.1 - 4.6 5.2 53.6 6.1 4.8 37.1 1.0 1 0 0 1 1 1 0 Utp14 protein Hid1 PF12722.2 CDI84752.1 - 1.4e-05 23.0 12.1 1.4e-05 23.0 8.4 1.1 1 0 0 1 1 1 1 High-temperature-induced dauer-formation protein Sec62 PF03839.11 CDI84752.1 - 3.2e-05 23.4 9.6 3.8e-05 23.1 6.7 1.1 1 0 0 1 1 1 1 Translocation protein Sec62 SAGA-Tad1 PF12767.2 CDI84752.1 - 3.4e-05 23.6 15.0 3.9e-05 23.4 10.4 1.3 1 0 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit SPX PF03105.14 CDI84752.1 - 8e-05 22.5 9.9 8e-05 22.5 6.9 1.2 1 0 0 1 1 1 1 SPX domain BatD PF13584.1 CDI84752.1 - 8.7e-05 21.2 1.3 8.7e-05 21.2 0.9 2.4 2 1 1 3 3 2 1 Oxygen tolerance Pex16 PF08610.5 CDI84752.1 - 0.0015 17.5 13.1 0.0018 17.3 9.1 1.2 1 0 0 1 1 1 1 Peroxisomal membrane protein (Pex16) RR_TM4-6 PF06459.7 CDI84752.1 - 0.0034 17.3 17.8 0.0034 17.3 12.4 1.6 2 0 0 2 2 2 1 Ryanodine Receptor TM 4-6 LMBR1 PF04791.11 CDI84752.1 - 0.0052 15.4 9.8 0.0061 15.2 6.8 1.2 1 0 0 1 1 1 1 LMBR1-like membrane protein NMDAR2_C PF10565.4 CDI84752.1 - 0.0069 15.1 19.0 0.0066 15.1 13.2 1.1 1 0 0 1 1 1 1 N-methyl D-aspartate receptor 2B3 C-terminus HlyD_2 PF12700.2 CDI84752.1 - 0.031 13.4 16.7 0.03 13.4 11.5 1.1 1 0 0 1 1 1 0 HlyD family secretion protein CDC45 PF02724.9 CDI84752.1 - 0.035 12.1 22.8 0.044 11.8 15.8 1.1 1 0 0 1 1 1 0 CDC45-like protein Plasmodium_Vir PF05795.6 CDI84752.1 - 0.05 12.8 6.7 0.064 12.4 4.6 1.4 1 1 0 1 1 1 0 Plasmodium vivax Vir protein CRT10 PF08728.5 CDI84752.1 - 0.065 11.2 7.6 0.056 11.4 5.3 1.0 1 0 0 1 1 1 0 CRT10 Ycf1 PF05758.7 CDI84752.1 - 0.065 10.9 26.0 0.076 10.7 18.0 1.1 1 0 0 1 1 1 0 Ycf1 SID-1_RNA_chan PF13965.1 CDI84752.1 - 0.2 9.8 12.7 0.28 9.3 8.8 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Raftlin PF15250.1 CDI84752.1 - 0.31 9.5 25.1 0.4 9.1 17.4 1.1 1 0 0 1 1 1 0 Raftlin Herpes_UL87 PF03043.9 CDI84752.1 - 0.64 8.3 17.5 0.75 8.1 12.1 1.1 1 0 0 1 1 1 0 Herpesvirus UL87 family BRF1 PF07741.8 CDI84752.1 - 0.86 9.8 28.9 0.011 15.8 3.9 3.0 1 1 1 2 2 1 0 Brf1-like TBP-binding domain 5_nucleotid PF05761.9 CDI84752.1 - 2.7 6.3 18.1 3.6 6.0 12.5 1.1 1 0 0 1 1 1 0 5' nucleotidase family DUF2347 PF09804.4 CDI84752.1 - 3.7 6.7 12.0 6.5 5.9 8.3 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2347) FAM60A PF15396.1 CDI84754.1 - 0.57 9.8 2.7 0.44 10.2 0.2 1.8 1 1 1 2 2 2 0 Protein Family FAM60A MSP1_C PF07462.6 CDI84754.1 - 0.92 7.8 12.8 1 7.6 8.9 1.1 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus DUF4139 PF13598.1 CDI84754.1 - 1.4 8.1 11.8 1.7 7.8 8.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4139) Golgin_A5 PF09787.4 CDI84754.1 - 2.3 6.6 5.7 2.7 6.4 4.0 1.0 1 0 0 1 1 1 0 Golgin subfamily A member 5 TFIIA PF03153.8 CDI84757.1 - 2.5 7.9 25.3 3 7.6 17.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PAT1 PF09770.4 CDI84757.1 - 5.8 5.0 45.3 5.9 4.9 31.4 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Med15 PF09606.5 CDI84757.1 - 8.2 4.4 46.3 11 4.1 32.1 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal YlqD PF11068.3 CDI84757.1 - 9.7 6.2 13.9 18 5.4 9.6 1.3 1 0 0 1 1 1 0 YlqD protein ELFV_dehydrog PF00208.16 CDI84758.1 - 1.5e-81 273.5 0.4 1.9e-81 273.2 0.3 1.1 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.13 CDI84758.1 - 7.9e-47 158.1 0.0 1.6e-46 157.1 0.0 1.5 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain NAD_binding_7 PF13241.1 CDI84758.1 - 0.0002 21.5 0.1 0.00068 19.8 0.0 1.9 2 0 0 2 2 2 1 Putative NAD(P)-binding 2-Hacid_dh_C PF02826.14 CDI84758.1 - 0.055 12.6 0.0 0.099 11.7 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Bac_GDH PF05088.7 CDI84758.1 - 0.076 10.4 0.0 0.11 9.9 0.0 1.1 1 0 0 1 1 1 0 Bacterial NAD-glutamate dehydrogenase Eno-Rase_NADH_b PF12242.3 CDI84761.1 - 1.4 8.7 7.4 0.19 11.5 1.4 2.3 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase TRAP_alpha PF03896.11 CDI84762.1 - 4.9 6.0 16.5 2.4 7.0 2.0 2.1 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit Med19 PF10278.4 CDI84762.1 - 7.2 6.2 32.3 1.3 8.6 10.8 2.2 2 0 0 2 2 2 0 Mediator of RNA pol II transcription subunit 19 Sec66 PF09802.4 CDI84763.1 - 8.6e-10 38.3 10.6 8.6e-10 38.3 7.3 2.7 2 1 0 3 3 3 1 Preprotein translocase subunit Sec66 DUF1635 PF07795.6 CDI84763.1 - 0.0017 17.7 4.0 0.0017 17.7 2.8 3.2 2 1 1 3 3 3 1 Protein of unknown function (DUF1635) FAM60A PF15396.1 CDI84763.1 - 5.1 6.7 37.2 4.2 7.0 2.7 2.6 2 0 0 2 2 2 0 Protein Family FAM60A Carb_anhydrase PF00194.16 CDI84766.1 - 1.2e-10 40.7 6.8 6e-07 28.7 0.0 3.8 3 1 1 4 4 4 2 Eukaryotic-type carbonic anhydrase Vfa1 PF08432.5 CDI84766.1 - 4.4 7.2 39.8 0.61 10.0 4.1 3.5 3 0 0 3 3 3 0 AAA-ATPase Vps4-associated protein 1 DUF3801 PF12687.2 CDI84767.1 - 0.71 9.4 20.8 0.69 9.4 3.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3801) Mitofilin PF09731.4 CDI84767.1 - 1.3 7.5 47.7 1.8 7.0 33.1 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Med15 PF09606.5 CDI84768.1 - 0.00053 18.3 23.8 0.00053 18.3 16.5 2.3 2 0 0 2 2 2 2 ARC105 or Med15 subunit of Mediator complex non-fungal SprA-related PF12118.3 CDI84768.1 - 0.0044 16.3 21.9 0.0044 16.3 15.2 2.6 2 1 0 2 2 2 1 SprA-related family Suf PF05843.9 CDI84768.1 - 0.0085 15.8 18.3 0.032 13.9 3.3 2.3 2 0 0 2 2 2 2 Suppressor of forked protein (Suf) DUF4063 PF13272.1 CDI84768.1 - 0.04 13.7 3.1 4.7 7.0 0.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4063) FimP PF09766.4 CDI84768.1 - 0.15 11.1 24.8 0.021 13.9 5.1 2.6 3 0 0 3 3 3 0 Fms-interacting protein zf-DHHC PF01529.15 CDI84768.1 - 0.17 11.2 5.6 0.17 11.2 0.3 2.3 2 0 0 2 2 2 0 DHHC palmitoyltransferase PAT1 PF09770.4 CDI84768.1 - 0.69 8.0 49.6 0.76 7.9 12.5 2.1 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 TFIIA PF03153.8 CDI84768.1 - 0.84 9.4 41.9 0.27 11.1 13.8 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit CD20 PF04103.10 CDI84768.1 - 1.8 8.4 4.8 16 5.3 0.3 2.7 2 0 0 2 2 2 0 CD20-like family DUF755 PF05501.6 CDI84771.1 - 0.0032 17.5 21.6 0.0032 17.5 15.0 9.0 9 0 0 9 9 9 2 Domain of unknown function (DUF755) Dehydrin PF00257.14 CDI84771.1 - 0.023 15.0 0.4 0.023 15.0 0.3 7.3 6 2 0 6 6 6 0 Dehydrin PAT1 PF09770.4 CDI84771.1 - 3.5 5.7 117.2 0.34 9.0 28.1 3.7 3 0 0 3 3 3 0 Topoisomerase II-associated protein PAT1 Na_trans_assoc PF06512.8 CDI84772.1 - 7.2 6.5 22.9 7.7 6.4 15.9 1.1 1 0 0 1 1 1 0 Sodium ion transport-associated SSP160 PF06933.6 CDI84773.1 - 0.0049 14.9 15.4 0.0058 14.6 10.7 1.0 1 0 0 1 1 1 1 Special lobe-specific silk protein SSP160 DUF912 PF06024.7 CDI84774.1 - 0.0076 16.2 0.2 0.018 15.0 0.1 1.7 1 0 0 1 1 1 1 Nucleopolyhedrovirus protein of unknown function (DUF912) ELL PF10390.4 CDI84774.1 - 0.036 13.2 1.5 0.035 13.3 1.0 1.1 1 0 0 1 1 1 0 RNA polymerase II elongation factor ELL IncA PF04156.9 CDI84774.1 - 0.05 13.1 5.6 0.084 12.4 3.9 1.5 1 0 0 1 1 1 0 IncA protein Macoilin PF09726.4 CDI84774.1 - 1.1 7.3 17.3 1.4 7.1 12.0 1.2 1 0 0 1 1 1 0 Transmembrane protein Ctr PF04145.10 CDI84774.1 - 2.1 8.4 6.4 0.36 10.8 0.7 2.0 1 1 1 2 2 2 0 Ctr copper transporter family Apt1 PF10351.4 CDI84774.1 - 3.3 6.4 13.2 4.3 6.0 9.1 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain HTH_Tnp_ISL3 PF13542.1 CDI84775.1 - 0.059 12.5 0.0 0.11 11.6 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 Secretin_N_2 PF07655.8 CDI84776.1 - 0.0014 19.0 5.9 0.0095 16.3 0.8 2.2 2 0 0 2 2 2 1 Secretin N-terminal domain TAF1_subA PF14929.1 CDI84776.1 - 0.0098 14.3 4.0 0.011 14.2 2.7 1.2 1 0 0 1 1 1 1 TAF RNA Polymerase I subunit A MMS19_C PF12460.3 CDI84776.1 - 0.026 13.2 12.7 0.036 12.7 8.8 1.1 1 0 0 1 1 1 0 RNAPII transcription regulator C-terminal MRP-S31 PF15433.1 CDI84776.1 - 0.048 13.0 14.7 0.056 12.8 10.2 1.1 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 SprA-related PF12118.3 CDI84776.1 - 0.11 11.8 22.6 0.15 11.3 15.6 1.2 1 0 0 1 1 1 0 SprA-related family DUF445 PF04286.7 CDI84776.1 - 0.11 11.9 9.5 0.15 11.5 6.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF445) HAUS4 PF14735.1 CDI84776.1 - 0.17 11.1 15.3 0.15 11.3 9.5 1.6 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 4 MRP-S27 PF10037.4 CDI84776.1 - 0.28 10.0 16.4 0.15 10.9 10.2 1.4 1 1 1 2 2 2 0 Mitochondrial 28S ribosomal protein S27 Hemerythrin PF01814.18 CDI84776.1 - 0.42 10.7 3.9 0.51 10.5 0.2 2.5 2 1 1 3 3 2 0 Hemerythrin HHE cation binding domain FliD_N PF02465.13 CDI84776.1 - 0.87 9.9 14.9 3.7 7.9 0.9 2.5 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus DUF4589 PF15252.1 CDI84776.1 - 0.93 9.2 10.2 2.4 7.9 7.1 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4589) AAA PF00004.24 CDI84776.1 - 1.1 9.4 7.3 0.16 12.1 0.5 2.2 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) PRCC PF10253.4 CDI84776.1 - 2.3 8.8 16.3 3.4 8.3 11.3 1.2 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting DASH_Spc19 PF08287.6 CDI84776.1 - 5.6 6.5 17.4 15 5.1 9.9 2.8 1 1 1 2 2 2 0 Spc19 DUF3881 PF12997.2 CDI84778.1 - 0.16 10.9 2.0 0.21 10.5 1.4 1.1 1 0 0 1 1 1 0 Domain of unknown function, E. rectale Gene description (DUF3881) CDK5_activator PF03261.10 CDI84778.1 - 2.5 7.3 12.9 3.2 7.0 9.0 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein Macoilin PF09726.4 CDI84778.1 - 7.2 4.7 15.6 8.3 4.5 10.8 1.0 1 0 0 1 1 1 0 Transmembrane protein SOBP PF15279.1 CDI84778.1 - 7.9 6.7 12.7 9.6 6.4 8.8 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein Sporozoite_P67 PF05642.6 CDI84779.1 - 0.0003 18.8 10.3 0.00039 18.4 7.2 1.2 1 0 0 1 1 1 1 Sporozoite P67 surface antigen HSP90 PF00183.13 CDI84779.1 - 0.091 11.1 9.3 0.12 10.7 6.4 1.2 1 0 0 1 1 1 0 Hsp90 protein BUD22 PF09073.5 CDI84779.1 - 0.26 10.3 12.7 1.7 7.6 0.0 2.1 2 0 0 2 2 2 0 BUD22 Plasmodium_Vir PF05795.6 CDI84779.1 - 0.48 9.5 3.6 4.2 6.4 0.3 2.1 2 0 0 2 2 2 0 Plasmodium vivax Vir protein TRAP_alpha PF03896.11 CDI84779.1 - 1.8 7.4 11.7 0.078 11.9 3.5 1.9 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit Ycf1 PF05758.7 CDI84779.1 - 5.1 4.6 7.8 6.9 4.2 5.4 1.1 1 0 0 1 1 1 0 Ycf1 Sigma70_ner PF04546.8 CDI84779.1 - 5.4 6.5 19.1 1.9 8.0 6.3 2.4 2 0 0 2 2 2 0 Sigma-70, non-essential region LIN37 PF15306.1 CDI84780.1 - 0.0068 16.4 0.5 0.0077 16.2 0.3 1.0 1 0 0 1 1 1 1 LIN37 BTV_NS2 PF04514.7 CDI84780.1 - 0.023 13.5 1.8 0.024 13.5 1.3 1.0 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Activator_LAG-3 PF11498.3 CDI84780.1 - 0.045 12.5 6.9 0.04 12.6 4.8 1.0 1 0 0 1 1 1 0 Transcriptional activator LAG-3 BAF1_ABF1 PF04684.8 CDI84780.1 - 0.09 11.6 2.2 0.077 11.8 1.5 1.0 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor APC_CDC26 PF10471.4 CDI84780.1 - 0.12 13.0 9.2 0.14 12.9 6.4 1.1 1 0 0 1 1 1 0 Anaphase-promoting complex APC subunit 1 Med3 PF11593.3 CDI84780.1 - 2.5 7.2 7.2 2.5 7.2 5.0 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DHC_N2 PF08393.8 CDI84781.1 - 1.9e-73 247.3 3.7 3.1e-73 246.6 2.5 1.3 1 0 0 1 1 1 1 Dynein heavy chain, N-terminal region 2 AAA_6 PF12774.2 CDI84782.1 - 2.3e-118 393.7 0.2 5.1e-118 392.6 0.1 1.6 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region D1 AAA_8 PF12780.2 CDI84782.1 - 2.5e-88 295.5 0.0 1.3e-86 289.9 0.0 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 AAA_7 PF12775.2 CDI84782.1 - 5.5e-73 245.4 0.0 1.2e-72 244.2 0.0 1.6 1 0 0 1 1 1 1 P-loop containing dynein motor region D3 MT PF12777.2 CDI84782.1 - 7.3e-37 126.8 13.9 1.7e-36 125.6 9.8 1.5 2 0 0 2 2 2 1 Microtubule-binding stalk of dynein motor DHC_N2 PF08393.8 CDI84782.1 - 2.2e-31 108.7 3.7 3.8e-31 107.9 0.0 3.0 4 0 0 4 4 4 1 Dynein heavy chain, N-terminal region 2 AAA_5 PF07728.9 CDI84782.1 - 5.1e-31 107.2 0.0 4.3e-12 45.9 0.0 5.5 5 1 0 5 5 4 3 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 CDI84782.1 - 9.5e-12 45.2 8.4 0.0004 20.4 0.0 6.9 7 1 1 8 8 7 2 AAA ATPase domain AAA_17 PF13207.1 CDI84782.1 - 3.1e-08 34.4 3.3 0.11 13.3 0.0 6.4 7 0 0 7 7 5 2 AAA domain AAA PF00004.24 CDI84782.1 - 2.2e-06 27.9 0.0 0.12 12.6 0.0 4.2 4 0 0 4 4 4 2 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.22 CDI84782.1 - 2.6e-06 27.7 0.4 0.0014 18.9 0.0 4.1 4 0 0 4 4 4 1 ABC transporter AAA_22 PF13401.1 CDI84782.1 - 7.2e-06 26.1 2.7 0.028 14.5 0.0 5.3 6 0 0 6 6 5 1 AAA domain AAA_18 PF13238.1 CDI84782.1 - 1.1e-05 25.7 0.3 0.64 10.3 0.0 4.7 5 0 0 5 5 4 2 AAA domain Mg_chelatase PF01078.16 CDI84782.1 - 2.8e-05 23.3 0.3 0.68 9.0 0.0 3.8 4 0 0 4 4 4 2 Magnesium chelatase, subunit ChlI AAA_33 PF13671.1 CDI84782.1 - 0.00012 21.9 0.2 0.22 11.4 0.0 4.9 5 0 0 5 5 4 1 AAA domain AAA_29 PF13555.1 CDI84782.1 - 0.00013 21.4 0.0 0.012 15.0 0.0 2.9 2 0 0 2 2 2 1 P-loop containing region of AAA domain Zeta_toxin PF06414.7 CDI84782.1 - 0.00015 20.8 0.1 0.13 11.3 0.0 4.0 4 0 0 4 4 4 1 Zeta toxin RNA_helicase PF00910.17 CDI84782.1 - 0.0002 21.4 0.0 12 6.1 0.0 4.4 4 0 0 4 4 3 0 RNA helicase AAA_30 PF13604.1 CDI84782.1 - 0.00023 20.8 3.8 3.2 7.3 0.0 4.2 4 0 0 4 4 4 1 AAA domain DUF815 PF05673.8 CDI84782.1 - 0.00067 18.6 0.0 0.041 12.8 0.0 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_14 PF13173.1 CDI84782.1 - 0.0013 18.6 0.0 0.066 13.1 0.0 3.0 3 0 0 3 3 2 1 AAA domain G-alpha PF00503.15 CDI84782.1 - 0.0032 16.2 1.8 0.0087 14.7 0.0 2.5 3 0 0 3 3 3 1 G-protein alpha subunit AAA_19 PF13245.1 CDI84782.1 - 0.014 15.1 0.5 16 5.3 0.4 3.8 3 0 0 3 3 3 0 Part of AAA domain UPF0079 PF02367.12 CDI84782.1 - 0.014 15.0 0.1 0.56 9.8 0.0 2.8 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 MobB PF03205.9 CDI84782.1 - 0.036 13.7 0.1 2 8.1 0.0 3.0 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B DUF87 PF01935.12 CDI84782.1 - 0.036 13.8 3.3 7.5 6.2 0.0 3.8 3 0 0 3 3 3 0 Domain of unknown function DUF87 Retrotrans_gag PF03732.12 CDI84782.1 - 0.33 11.0 7.6 0.33 11.0 0.3 4.0 5 0 0 5 5 3 0 Retrotransposon gag protein CHASE3 PF05227.8 CDI84782.1 - 0.71 9.5 14.8 0.86 9.2 8.2 2.4 2 0 0 2 2 2 0 CHASE3 domain Ribosomal_60s PF00428.14 CDI84783.1 - 0.0069 16.7 10.1 0.0069 16.7 7.0 2.4 2 0 0 2 2 2 1 60s Acidic ribosomal protein DUF1697 PF08002.6 CDI84784.1 - 0.18 11.8 9.7 0.31 11.0 6.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1697) PAT1 PF09770.4 CDI84784.1 - 0.99 7.5 58.7 1.4 7.0 40.7 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 FUSC PF04632.7 CDI84784.1 - 3.1 6.1 10.5 3.2 6.0 7.2 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Med15 PF09606.5 CDI84785.1 - 0.0014 16.8 24.3 0.0016 16.7 16.9 1.2 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal SprA-related PF12118.3 CDI84785.1 - 0.0024 17.2 33.6 0.0029 16.9 23.3 1.1 1 0 0 1 1 1 1 SprA-related family Suf PF05843.9 CDI84785.1 - 0.052 13.2 20.6 0.06 13.0 14.3 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) RR_TM4-6 PF06459.7 CDI84785.1 - 0.097 12.5 11.2 0.11 12.3 7.8 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF737 PF05300.6 CDI84785.1 - 0.12 12.3 16.7 0.17 11.8 11.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF737) PAT1 PF09770.4 CDI84785.1 - 0.19 9.9 25.5 0.2 9.8 17.7 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Peptidase_S49_N PF08496.5 CDI84785.1 - 0.27 10.9 6.2 0.31 10.8 4.3 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF4175 PF13779.1 CDI84785.1 - 0.32 8.6 26.6 0.36 8.4 18.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Serinc PF03348.10 CDI84785.1 - 0.42 9.2 16.6 0.47 9.0 11.5 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) DUF3682 PF12446.3 CDI84785.1 - 0.61 10.3 34.0 1.1 9.5 23.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) Utp14 PF04615.8 CDI84785.1 - 0.72 7.9 20.3 0.8 7.7 14.1 1.0 1 0 0 1 1 1 0 Utp14 protein Dicty_REP PF05086.7 CDI84785.1 - 1.2 6.8 18.1 1.4 6.6 12.6 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Sec62 PF03839.11 CDI84785.1 - 1.4 8.2 9.2 1.6 8.0 6.4 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 Raftlin PF15250.1 CDI84785.1 - 1.7 7.0 20.9 2 6.8 14.5 1.0 1 0 0 1 1 1 0 Raftlin Tim54 PF11711.3 CDI84785.1 - 1.8 7.0 8.8 1.9 6.9 6.1 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DUF2201_N PF13203.1 CDI84785.1 - 2.1 7.4 19.1 2.9 6.9 13.3 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain FLO_LFY PF01698.11 CDI84785.1 - 2.2 7.0 16.1 2.6 6.8 11.2 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein OmpH PF03938.9 CDI84785.1 - 2.2 8.1 22.6 2.9 7.8 15.6 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) 5_nucleotid PF05761.9 CDI84785.1 - 2.4 6.5 8.9 2.8 6.3 6.2 1.1 1 0 0 1 1 1 0 5' nucleotidase family DDHD PF02862.12 CDI84785.1 - 3.4 7.3 26.1 4.9 6.8 18.1 1.2 1 0 0 1 1 1 0 DDHD domain TFIIA PF03153.8 CDI84785.1 - 3.7 7.3 29.6 4 7.2 20.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4407 PF14362.1 CDI84785.1 - 3.9 6.3 8.9 4.4 6.1 6.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Macoilin PF09726.4 CDI84785.1 - 4.2 5.5 33.1 6 5.0 23.0 1.3 1 0 0 1 1 1 0 Transmembrane protein G0-G1_switch_2 PF15103.1 CDI84785.1 - 4.5 7.5 7.4 7.1 6.9 5.1 1.4 1 0 0 1 1 1 0 G0/G1 switch protein 2 DUF605 PF04652.11 CDI84785.1 - 4.7 6.4 33.6 5.6 6.2 23.3 1.0 1 0 0 1 1 1 0 Vta1 like AUX_IAA PF02309.11 CDI84785.1 - 5.3 6.7 17.2 7.1 6.3 11.9 1.3 1 0 0 1 1 1 0 AUX/IAA family DUF1675 PF07897.6 CDI84785.1 - 6.6 6.5 27.9 7.9 6.2 19.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) PI3K_1B_p101 PF10486.4 CDI84785.1 - 7.1 4.0 17.8 7.9 3.9 12.4 1.0 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit SOBP PF15279.1 CDI84785.1 - 7.4 6.8 27.8 8.2 6.7 19.3 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein GPCR_chapero_1 PF11904.3 CDI84785.1 - 8.5 5.4 19.6 11 5.0 13.6 1.2 1 0 0 1 1 1 0 GPCR-chaperone THDPS_N_2 PF14805.1 CDI84786.1 - 0.046 13.5 0.0 0.046 13.5 0.0 2.1 3 0 0 3 3 3 0 Tetrahydrodipicolinate N-succinyltransferase N-terminal Presenilin PF01080.12 CDI84786.1 - 0.33 9.7 4.4 0.6 8.8 3.0 1.4 1 1 0 1 1 1 0 Presenilin DUF912 PF06024.7 CDI84786.1 - 1.4 9.0 14.9 0.15 12.1 0.4 3.1 3 0 0 3 3 3 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DHHW PF14286.1 CDI84786.1 - 2 7.6 12.3 0.21 10.8 5.1 1.7 1 1 1 2 2 2 0 DHHW protein PBP1_TM PF14812.1 CDI84786.1 - 2.2 8.6 6.8 8.8 6.7 0.3 3.1 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Conotoxin PF02950.12 CDI84786.1 - 8.1 7.3 17.8 0.28 12.0 1.5 3.1 3 0 0 3 3 3 0 Conotoxin Sulfate_tra_GLY PF13792.1 CDI84787.1 - 2.9e-25 87.7 0.4 2.9e-25 87.7 0.3 2.4 2 0 0 2 2 2 1 Sulfate transporter N-terminal domain with GLY motif Sulfate_transp PF00916.15 CDI84787.1 - 2.3e-08 33.3 0.1 3.9e-08 32.6 0.1 1.3 1 0 0 1 1 1 1 Sulfate transporter family zf-MIZ PF02891.15 CDI84788.1 - 1.8e-15 56.1 8.6 2.1e-15 55.9 3.0 2.7 2 0 0 2 2 2 1 MIZ/SP-RING zinc finger SAP PF02037.22 CDI84788.1 - 2.8e-07 29.8 0.0 6.6e-07 28.6 0.0 1.7 1 0 0 1 1 1 1 SAP domain PHD_2 PF13831.1 CDI84788.1 - 0.00015 20.9 4.5 0.00015 20.9 3.1 2.6 2 1 0 2 2 2 1 PHD-finger PHD PF00628.24 CDI84788.1 - 0.0025 17.4 16.0 0.011 15.4 4.8 2.8 2 0 0 2 2 2 2 PHD-finger Prok-RING_1 PF14446.1 CDI84788.1 - 0.033 13.9 2.7 0.18 11.5 1.0 2.8 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 Ctr PF04145.10 CDI84789.1 - 0.053 13.5 0.0 0.15 12.1 0.0 1.7 2 0 0 2 2 2 0 Ctr copper transporter family SR-25 PF10500.4 CDI84791.1 - 0.062 12.7 9.8 0.098 12.1 6.8 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF572 PF04502.8 CDI84791.1 - 0.065 12.4 7.3 0.07 12.3 5.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Neur_chan_memb PF02932.11 CDI84791.1 - 0.11 12.3 1.8 0.13 12.1 1.2 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region TMEM51 PF15345.1 CDI84791.1 - 0.11 12.1 8.4 0.14 11.8 5.8 1.4 1 0 0 1 1 1 0 Transmembrane protein 51 Hid1 PF12722.2 CDI84791.1 - 0.12 10.0 6.3 0.13 9.9 4.4 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Cellulose_synt PF03552.9 CDI84791.1 - 0.22 9.7 3.7 0.24 9.6 2.5 1.1 1 0 0 1 1 1 0 Cellulose synthase PAT1 PF09770.4 CDI84791.1 - 0.24 9.6 16.8 0.23 9.6 11.7 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 CIAPIN1 PF05093.8 CDI84791.1 - 0.29 11.2 5.7 0.54 10.3 3.9 1.6 1 0 0 1 1 1 0 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis YjgP_YjgQ PF03739.9 CDI84791.1 - 0.29 9.8 6.2 0.47 9.1 4.3 1.3 1 0 0 1 1 1 0 Predicted permease YjgP/YjgQ family DUF2217 PF10265.4 CDI84791.1 - 0.4 9.3 6.9 0.47 9.1 4.8 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) DUF966 PF06136.8 CDI84791.1 - 0.64 9.3 9.5 0.72 9.2 6.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Peptidase_S64 PF08192.6 CDI84791.1 - 0.91 7.7 7.8 0.94 7.7 5.4 1.1 1 0 0 1 1 1 0 Peptidase family S64 NST1 PF13945.1 CDI84791.1 - 1 9.4 14.6 1.4 8.9 10.1 1.2 1 0 0 1 1 1 0 Salt tolerance down-regulator Bud13 PF09736.4 CDI84791.1 - 1.1 9.5 9.7 1.5 9.0 6.7 1.1 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex FAM60A PF15396.1 CDI84791.1 - 1.8 8.2 9.3 2.5 7.8 6.4 1.1 1 0 0 1 1 1 0 Protein Family FAM60A FemAB PF02388.11 CDI84791.1 - 3.8 6.0 13.1 5.2 5.6 9.1 1.2 1 0 0 1 1 1 0 FemAB family Ycf1 PF05758.7 CDI84791.1 - 4.7 4.7 7.3 5.4 4.5 5.0 1.0 1 0 0 1 1 1 0 Ycf1 AUX_IAA PF02309.11 CDI84791.1 - 4.8 6.8 8.6 6.1 6.5 6.0 1.1 1 0 0 1 1 1 0 AUX/IAA family DNA_pol_viral_N PF00242.12 CDI84791.1 - 6 5.7 10.3 7.1 5.5 7.1 1.1 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain DUF1510 PF07423.6 CDI84792.1 - 8.9e-06 25.2 24.5 6.7e-05 22.3 10.0 2.3 1 1 1 2 2 2 1 Protein of unknown function (DUF1510) Pex24p PF06398.6 CDI84792.1 - 0.00011 21.1 1.6 0.00011 21.1 1.1 2.1 1 1 1 2 2 2 1 Integral peroxisomal membrane peroxin IncA PF04156.9 CDI84792.1 - 0.00023 20.8 27.6 0.00023 20.8 19.2 2.2 1 1 1 2 2 1 1 IncA protein Pex14_N PF04695.8 CDI84792.1 - 0.0019 18.2 17.0 0.0019 18.2 11.8 3.2 2 1 1 3 3 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region O-antigen_lig PF13425.1 CDI84792.1 - 0.0022 18.0 1.4 0.046 13.7 0.0 2.5 2 1 0 2 2 2 1 O-antigen ligase like membrane protein CD20 PF04103.10 CDI84792.1 - 0.0041 17.0 15.5 1.8 8.4 0.2 3.4 2 1 0 2 2 2 1 CD20-like family DUF4131 PF13567.1 CDI84792.1 - 0.0044 16.4 26.4 0.025 13.9 9.3 2.4 1 1 1 2 2 2 2 Domain of unknown function (DUF4131) DUF3464 PF11947.3 CDI84792.1 - 0.0053 16.2 3.1 0.0053 16.2 2.2 2.6 2 1 0 2 2 1 1 Protein of unknown function (DUF3464) Plasmodium_Vir PF05795.6 CDI84792.1 - 0.0061 15.8 3.0 0.0061 15.8 2.1 1.8 1 1 1 2 2 2 1 Plasmodium vivax Vir protein BatD PF13584.1 CDI84792.1 - 0.0079 14.8 4.6 0.0079 14.8 3.2 3.8 1 1 3 4 4 3 1 Oxygen tolerance FAM176 PF14851.1 CDI84792.1 - 0.0085 15.7 7.0 0.0085 15.7 4.8 2.8 2 2 1 3 3 1 1 FAM176 family Dehydrin PF00257.14 CDI84792.1 - 0.01 16.1 10.0 0.01 16.1 7.0 2.3 2 0 0 2 2 1 0 Dehydrin N6_N4_Mtase PF01555.13 CDI84792.1 - 0.012 15.0 0.0 0.057 12.8 0.0 1.9 1 1 0 1 1 1 0 DNA methylase Wzy_C PF04932.10 CDI84792.1 - 0.018 14.8 3.5 0.13 12.0 2.3 2.2 1 1 0 1 1 1 0 O-Antigen ligase DUF443 PF04276.7 CDI84792.1 - 0.021 14.2 4.4 3.3 7.0 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF443) Neur_chan_memb PF02932.11 CDI84792.1 - 0.029 14.2 24.1 0.13 12.1 16.7 1.8 1 1 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Reticulon PF02453.12 CDI84792.1 - 0.11 12.1 8.0 0.12 12.0 4.1 2.1 1 1 1 2 2 2 0 Reticulon Peptidase_M50B PF13398.1 CDI84792.1 - 0.28 10.5 9.3 0.15 11.3 3.9 2.0 2 0 0 2 2 2 0 Peptidase M50B-like Parvo_coat PF00740.13 CDI84792.1 - 0.28 10.0 30.3 0.39 9.6 21.0 1.1 1 0 0 1 1 1 0 Parvovirus coat protein VP2 Polysacc_synt PF01943.12 CDI84792.1 - 0.31 10.2 12.2 0.47 9.6 6.1 2.1 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Herpes_UL87 PF03043.9 CDI84792.1 - 0.33 9.2 21.2 0.4 9.0 14.7 1.1 1 0 0 1 1 1 0 Herpesvirus UL87 family DUF3450 PF11932.3 CDI84792.1 - 0.37 10.0 51.8 0.044 13.0 18.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) ABC_membrane PF00664.18 CDI84792.1 - 0.39 10.0 9.4 0.14 11.5 4.0 1.9 2 0 0 2 2 2 0 ABC transporter transmembrane region NfeD PF01957.13 CDI84792.1 - 0.41 10.7 3.6 1.3 9.2 0.8 2.4 2 0 0 2 2 2 0 NfeD-like C-terminal, partner-binding Herpes_env PF01673.13 CDI84792.1 - 0.44 9.0 21.5 0.72 8.3 14.9 1.3 1 0 0 1 1 1 0 Herpesvirus putative major envelope glycoprotein YfhO PF09586.5 CDI84792.1 - 0.55 8.1 31.8 6.2 4.6 22.0 2.3 1 1 0 1 1 1 0 Bacterial membrane protein YfhO TRAP_alpha PF03896.11 CDI84792.1 - 0.8 8.6 17.0 0.0092 15.0 5.2 2.5 1 1 2 3 3 3 0 Translocon-associated protein (TRAP), alpha subunit SKN1 PF03935.10 CDI84792.1 - 1.2 7.1 11.5 0.096 10.8 2.0 2.3 1 1 1 2 2 2 0 Beta-glucan synthesis-associated protein (SKN1) SpoIIIAH PF12685.2 CDI84792.1 - 1.2 8.5 33.0 4.4 6.7 15.1 3.4 1 1 1 2 2 2 0 SpoIIIAH-like protein FPN1 PF06963.7 CDI84792.1 - 1.3 7.2 14.3 0.037 12.4 3.9 2.1 2 0 0 2 2 2 0 Ferroportin1 (FPN1) AIF_C PF14721.1 CDI84792.1 - 1.3 9.2 22.5 0.14 12.4 5.6 2.5 2 1 1 3 3 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Nucleoside_tran PF01733.13 CDI84792.1 - 1.5 7.9 17.9 0.0098 15.0 5.2 2.0 1 1 0 2 2 2 0 Nucleoside transporter 7TM_GPCR_Srw PF10324.4 CDI84792.1 - 1.9 7.5 10.7 3.8 6.5 7.4 1.5 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srw ATG22 PF11700.3 CDI84792.1 - 2.1 6.7 18.1 4.7 5.5 12.5 1.8 1 1 0 1 1 1 0 Vacuole effluxer Atg22 like GRA6 PF05084.8 CDI84792.1 - 2.2 7.7 10.3 0.25 10.8 4.1 1.6 1 1 0 1 1 1 0 Granule antigen protein (GRA6) Endonuc_Holl PF10107.4 CDI84792.1 - 2.5 7.7 34.3 1.7 8.3 14.2 2.2 2 0 0 2 2 2 0 Endonuclease related to archaeal Holliday junction resolvase Ribosomal_60s PF00428.14 CDI84792.1 - 3.2 8.2 7.9 1.5 9.2 3.7 1.7 2 0 0 2 2 1 0 60s Acidic ribosomal protein DUF2244 PF10003.4 CDI84792.1 - 3.3 7.0 15.5 0.49 9.7 3.6 2.7 2 1 1 3 3 3 0 Integral membrane protein (DUF2244) DUF3112 PF11309.3 CDI84792.1 - 3.4 7.4 6.6 28 4.4 0.0 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF3112) PRA1 PF03208.14 CDI84792.1 - 3.6 6.9 15.6 8.6 5.6 8.2 2.7 2 1 0 2 2 1 0 PRA1 family protein Tetraspannin PF00335.15 CDI84792.1 - 3.6 6.7 25.0 1.1 8.4 0.6 2.9 1 1 1 2 2 2 0 Tetraspanin family DUF1430 PF07242.6 CDI84792.1 - 3.7 7.6 12.9 1.9 8.6 5.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1430) Amastin PF07344.6 CDI84792.1 - 3.8 7.1 8.8 1.1 8.8 0.1 2.9 2 1 1 3 3 3 0 Amastin surface glycoprotein DUF2749 PF10907.3 CDI84792.1 - 4.2 7.2 8.3 12 5.8 0.3 3.2 2 1 2 4 4 2 0 Protein of unknown function (DUF2749) TLC PF03219.9 CDI84792.1 - 4.9 5.4 11.9 0.77 8.1 2.3 2.3 1 1 1 2 2 2 0 TLC ATP/ADP transporter 7TM_GPCR_Sru PF10322.4 CDI84792.1 - 6.1 5.8 8.6 9.1 5.2 1.0 2.6 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Sru DUF3357 PF11837.3 CDI84792.1 - 6.4 6.6 34.8 0.11 12.4 1.4 4.4 1 1 3 4 4 3 0 Domain of unknown function (DUF3357) DUF2126 PF09899.4 CDI84792.1 - 6.6 4.6 26.7 0.23 9.4 9.5 2.0 2 0 0 2 2 2 0 Putative amidoligase enzyme (DUF2126) P5-ATPase PF12409.3 CDI84792.1 - 6.7 6.5 14.0 0.16 11.7 1.8 2.8 3 0 0 3 3 3 0 P5-type ATPase cation transporter DUF2561 PF10812.3 CDI84792.1 - 8.2 5.9 14.8 0.047 13.2 2.4 2.3 1 1 2 3 3 3 0 Protein of unknown function (DUF2561) SID-1_RNA_chan PF13965.1 CDI84792.1 - 8.3 4.4 23.0 0.34 9.0 7.6 2.1 1 1 1 2 2 2 0 dsRNA-gated channel SID-1 Med15 PF09606.5 CDI84792.1 - 8.8 4.3 95.2 11 4.0 66.0 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal RR_TM4-6 PF06459.7 CDI84792.1 - 9.6 6.0 28.7 2 8.2 11.5 2.1 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 DUF4010 PF13194.1 CDI84792.1 - 9.9 5.3 19.2 0.21 10.8 2.9 3.2 2 1 0 3 3 3 0 Domain of unknown function (DUF4010) Ribosomal_60s PF00428.14 CDI84793.1 - 0.0099 16.2 4.3 0.0099 16.2 3.0 6.0 4 2 1 5 5 5 2 60s Acidic ribosomal protein AT_hook PF02178.14 CDI84793.1 - 0.12 12.1 3.5 0.33 10.7 2.4 1.8 1 0 0 1 1 1 0 AT hook motif CDK2AP PF09806.4 CDI84794.1 - 0.018 15.2 13.9 0.018 15.2 9.6 6.5 2 2 2 4 4 4 0 Cyclin-dependent kinase 2-associated protein Gpi16 PF04113.9 CDI84795.1 - 6.8e-16 57.4 2.4 3.7e-07 28.5 0.1 2.8 3 1 0 3 3 3 2 Gpi16 subunit, GPI transamidase component Shisa PF13908.1 CDI84795.1 - 3e-05 24.2 10.5 3e-05 24.2 7.3 3.8 4 0 0 4 4 4 1 Wnt and FGF inhibitory regulator Neur_chan_memb PF02932.11 CDI84795.1 - 0.00027 20.8 3.6 0.00027 20.8 2.5 2.6 2 2 0 2 2 2 1 Neurotransmitter-gated ion-channel transmembrane region IncA PF04156.9 CDI84795.1 - 0.0024 17.4 11.6 0.0024 17.4 8.0 4.9 5 0 0 5 5 4 1 IncA protein Protocadherin PF08374.6 CDI84795.1 - 0.0081 15.8 1.9 0.0081 15.8 1.3 2.2 2 0 0 2 2 2 1 Protocadherin DUF1980 PF09323.5 CDI84795.1 - 0.011 15.4 0.4 0.011 15.4 0.3 3.4 4 0 0 4 4 4 0 Domain of unknown function (DUF1980) DUF4446 PF14584.1 CDI84795.1 - 0.014 15.1 6.1 0.014 15.1 4.2 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF4446) DUF2722 PF10846.3 CDI84795.1 - 0.034 13.1 0.1 0.034 13.1 0.0 3.9 3 1 0 4 4 3 0 Protein of unknown function (DUF2722) SID-1_RNA_chan PF13965.1 CDI84795.1 - 0.34 9.0 6.3 0.07 11.2 1.4 1.9 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 DUF1510 PF07423.6 CDI84795.1 - 0.42 9.9 19.9 0.018 14.4 4.3 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1510) DUF3112 PF11309.3 CDI84795.1 - 2.3 7.9 0.0 2.3 7.9 0.0 2.8 2 1 0 3 3 3 0 Protein of unknown function (DUF3112) SET PF00856.23 CDI84795.1 - 2.6 8.3 5.7 0.47 10.7 0.7 2.3 2 1 0 2 2 1 0 SET domain BNR_3 PF13859.1 CDI84795.1 - 3.5 6.6 6.9 1.9 7.4 2.7 2.0 2 0 0 2 2 2 0 BNR repeat-like domain DUF4557 PF15101.1 CDI84795.1 - 4 7.2 49.0 0.022 14.6 8.6 4.2 4 0 0 4 4 4 0 Domain of unknown function (DUF4557) 2OG-FeII_Oxy_5 PF13759.1 CDI84795.1 - 6.3 7.1 0.0 6.3 7.1 0.0 4.0 5 0 0 5 5 4 0 Putative 2OG-Fe(II) oxygenase AAA_23 PF13476.1 CDI84796.1 - 0.012 16.0 6.3 0.012 15.9 4.4 1.1 1 0 0 1 1 1 0 AAA domain Cwf_Cwc_15 PF04889.7 CDI84796.1 - 0.017 14.8 13.7 0.023 14.3 9.5 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein SprA-related PF12118.3 CDI84796.1 - 0.18 11.0 41.5 0.22 10.8 28.8 1.1 1 0 0 1 1 1 0 SprA-related family Med15 PF09606.5 CDI84796.1 - 0.6 8.2 45.8 0.69 8.0 31.7 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal SDA1 PF05285.7 CDI84796.1 - 0.69 9.1 15.5 0.77 8.9 10.8 1.1 1 0 0 1 1 1 0 SDA1 Rtf2 PF04641.7 CDI84796.1 - 0.72 9.0 17.4 0.95 8.6 12.0 1.2 1 0 0 1 1 1 0 Rtf2 RING-finger Conotoxin PF02950.12 CDI84796.1 - 1 10.2 15.3 5.1 7.9 0.4 2.4 2 0 0 2 2 2 0 Conotoxin FLO_LFY PF01698.11 CDI84796.1 - 2.6 6.7 16.5 3.4 6.4 11.5 1.3 1 0 0 1 1 1 0 Floricaula / Leafy protein BTV_NS2 PF04514.7 CDI84796.1 - 3 6.6 11.8 3.7 6.3 8.2 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 TFIIA PF03153.8 CDI84796.1 - 3.2 7.5 36.8 4 7.2 25.5 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Raftlin PF15250.1 CDI84796.1 - 3.4 6.0 18.5 4.8 5.6 12.8 1.3 1 0 0 1 1 1 0 Raftlin RR_TM4-6 PF06459.7 CDI84796.1 - 3.7 7.3 14.3 5 6.9 9.9 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Ribosomal_60s PF00428.14 CDI84796.1 - 4.3 7.7 9.7 9.1 6.7 6.7 1.6 1 0 0 1 1 1 0 60s Acidic ribosomal protein Trp_oprn_chp PF09534.5 CDI84796.1 - 5.1 6.6 15.3 0.6 9.6 4.4 2.1 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) PAT1 PF09770.4 CDI84796.1 - 7 4.7 38.9 7.3 4.6 26.9 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Dehydrin PF00257.14 CDI84797.1 - 0.00034 20.9 10.8 0.00034 20.9 7.5 5.2 3 1 0 3 3 3 1 Dehydrin Spore_coat_CotO PF14153.1 CDI84798.1 - 8.5e-05 22.0 19.7 9.8e-05 21.8 13.7 1.3 1 0 0 1 1 1 1 Spore coat protein CotO DDRGK PF09756.4 CDI84798.1 - 0.091 12.1 27.3 0.14 11.5 18.9 1.3 1 0 0 1 1 1 0 DDRGK domain TT_ORF1 PF02956.9 CDI84798.1 - 0.15 10.4 15.8 0.16 10.3 10.9 1.2 1 0 0 1 1 1 0 TT viral orf 1 PAT1 PF09770.4 CDI84798.1 - 0.24 9.5 56.8 0.31 9.2 39.3 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 NARP1 PF12569.3 CDI84798.1 - 0.68 8.6 21.1 0.92 8.1 14.6 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Daxx PF03344.10 CDI84798.1 - 0.83 8.0 31.3 1 7.7 21.7 1.1 1 0 0 1 1 1 0 Daxx Family DUF4638 PF15472.1 CDI84798.1 - 0.85 9.1 17.1 1.1 8.8 11.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) eIF-3_zeta PF05091.7 CDI84798.1 - 1.5 7.3 29.8 2.2 6.8 20.7 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Tim54 PF11711.3 CDI84798.1 - 3.4 6.1 15.9 4.6 5.7 11.0 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 eIF3_subunit PF08597.5 CDI84798.1 - 3.9 6.9 20.4 5.3 6.5 14.1 1.2 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit BTV_NS2 PF04514.7 CDI84798.1 - 4.4 6.1 19.5 5.6 5.7 13.5 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Med15 PF09606.5 CDI84798.1 - 5.4 5.0 72.9 7.6 4.5 50.6 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal OmpH PF03938.9 CDI84798.1 - 6.4 6.6 43.0 10 5.9 29.8 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Trypan_glycop_C PF10659.4 CDI84799.1 - 0.41 10.9 14.0 0.99 9.7 3.0 2.4 2 0 0 2 2 2 0 Trypanosome variant surface glycoprotein C-terminal domain SID-1_RNA_chan PF13965.1 CDI84799.1 - 1.2 7.1 14.8 1.6 6.8 10.3 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DUF4063 PF13272.1 CDI84799.1 - 1.3 8.8 4.8 4.5 7.1 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4063) PAT1 PF09770.4 CDI84799.1 - 1.4 7.0 65.8 1.7 6.8 45.6 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 BNR_3 PF13859.1 CDI84799.1 - 2 7.4 8.5 2.6 7.0 5.9 1.2 1 0 0 1 1 1 0 BNR repeat-like domain DUF2391 PF09622.5 CDI84799.1 - 2.8 6.9 4.8 4.3 6.4 3.3 1.3 1 0 0 1 1 1 0 Putative integral membrane protein (DUF2391) Erv26 PF04148.8 CDI84799.1 - 5.4 6.3 9.8 1.8 7.8 1.0 2.2 2 0 0 2 2 2 0 Transmembrane adaptor Erv26 DUF3006 PF11213.3 CDI84799.1 - 7.1 6.4 8.6 13 5.6 0.4 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF3006) Thioredoxin PF00085.15 CDI84801.1 - 1e-05 25.1 0.0 0.027 14.1 0.0 2.3 2 0 0 2 2 2 2 Thioredoxin Glutaredoxin PF00462.19 CDI84801.1 - 0.00056 19.8 0.4 0.0031 17.4 0.0 2.5 3 0 0 3 3 3 1 Glutaredoxin Thioredoxin_3 PF13192.1 CDI84801.1 - 0.002 17.9 0.0 1.9 8.3 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin domain DUF3785 PF12653.2 CDI84801.1 - 0.0048 16.7 0.1 0.0086 15.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3785) Thioredoxin_2 PF13098.1 CDI84801.1 - 0.032 14.4 0.0 0.25 11.5 0.0 2.3 2 1 0 2 2 2 0 Thioredoxin-like domain Asp_protease_2 PF13650.1 CDI84803.1 - 1.2e-07 32.1 0.0 3.6e-07 30.5 0.0 1.9 2 0 0 2 2 2 1 Aspartyl protease RVP_2 PF08284.6 CDI84803.1 - 3.9e-06 26.8 0.0 6.7e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 CDI84803.1 - 5.2e-06 26.1 0.0 1.2e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.15 CDI84803.1 - 1.2e-05 25.1 0.0 2.5e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.5 CDI84803.1 - 0.1 12.1 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 Aspartyl protease GCC2_GCC3 PF07699.8 CDI84805.1 - 2.5e-08 33.3 6.6 1.3e-06 27.9 0.5 3.0 1 1 1 2 2 2 2 GCC2 and GCC3 RGS PF00615.14 CDI84805.1 - 0.5 10.4 3.0 0.42 10.7 0.3 2.2 2 0 0 2 2 2 0 Regulator of G protein signaling domain NHL PF01436.16 CDI84806.1 - 1.3e-10 40.6 0.2 0.32 11.0 0.0 6.0 5 0 0 5 5 5 4 NHL repeat SGL PF08450.7 CDI84806.1 - 1.2e-08 34.6 0.1 2.1e-06 27.3 0.0 2.3 1 1 1 2 2 2 2 SMP-30/Gluconolaconase/LRE-like region Lactonase PF10282.4 CDI84806.1 - 0.00017 20.8 0.0 0.00058 19.0 0.0 1.8 1 1 1 2 2 2 2 Lactonase, 7-bladed beta-propeller F5_F8_type_C PF00754.20 CDI84806.1 - 0.00082 19.2 0.1 0.0021 17.8 0.1 1.6 1 0 0 1 1 1 1 F5/8 type C domain Arylesterase PF01731.15 CDI84806.1 - 0.069 13.1 0.0 0.39 10.7 0.0 2.3 1 1 1 2 2 2 0 Arylesterase Ribosomal_60s PF00428.14 CDI84807.1 - 0.0048 17.2 23.4 0.0048 17.2 16.2 3.0 1 1 2 3 3 3 1 60s Acidic ribosomal protein Med15 PF09606.5 CDI84807.1 - 0.23 9.6 94.8 0.27 9.3 65.7 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal MSP1_C PF07462.6 CDI84807.1 - 0.69 8.2 17.3 0.84 7.9 12.0 1.3 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus DUF2910 PF11139.3 CDI84807.1 - 0.71 8.9 11.7 0.6 9.2 7.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2910) TLC PF03219.9 CDI84807.1 - 0.92 7.9 2.6 1.3 7.4 1.8 1.3 1 0 0 1 1 1 0 TLC ATP/ADP transporter Hydrolase_3 PF08282.7 CDI84807.1 - 1 8.8 11.7 1.4 8.4 8.1 1.2 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase DUF1180 PF06679.7 CDI84807.1 - 1.1 9.1 12.5 0.7 9.7 7.4 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1180) Hid1 PF12722.2 CDI84807.1 - 1.9 6.0 23.2 1.8 6.1 16.1 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein PAT1 PF09770.4 CDI84807.1 - 7 4.7 77.5 8.3 4.5 53.7 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 GAGA_bind PF06217.7 CDI84807.1 - 7.2 6.4 26.7 10 5.9 18.5 1.4 1 0 0 1 1 1 0 GAGA binding protein-like family Mem_trans PF03547.13 CDI84807.1 - 8.5 4.5 11.9 12 4.0 8.2 1.4 1 0 0 1 1 1 0 Membrane transport protein Rifin_STEVOR PF02009.11 CDI84808.1 - 0.01 15.5 20.3 0.015 14.9 14.1 1.2 1 0 0 1 1 1 0 Rifin/stevor family EcsB PF05975.7 CDI84808.1 - 0.026 12.9 1.4 0.059 11.8 1.0 1.6 1 0 0 1 1 1 0 Bacterial ABC transporter protein EcsB Spc7_N PF15402.1 CDI84808.1 - 0.15 10.0 31.5 0.19 9.6 21.9 1.2 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 SAGA-Tad1 PF12767.2 CDI84808.1 - 0.16 11.6 32.8 0.23 11.1 22.7 1.2 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit Macoilin PF09726.4 CDI84808.1 - 0.19 9.9 37.0 0.23 9.6 25.6 1.0 1 0 0 1 1 1 0 Transmembrane protein Dapper PF15268.1 CDI84808.1 - 0.29 9.8 36.2 0.36 9.5 25.1 1.1 1 0 0 1 1 1 0 Dapper DUF572 PF04502.8 CDI84808.1 - 0.37 9.9 32.5 0.41 9.8 22.5 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF572) ODV-E18 PF10717.4 CDI84808.1 - 0.42 10.0 16.8 1.4 8.3 11.4 2.2 1 1 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 PLRV_ORF5 PF01690.12 CDI84808.1 - 0.68 9.0 28.2 0.76 8.8 19.5 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Cyto_ox_2 PF02322.10 CDI84808.1 - 0.79 8.8 3.8 1.1 8.3 2.6 1.1 1 0 0 1 1 1 0 Cytochrome oxidase subunit II DUF3595 PF12166.3 CDI84808.1 - 2.3 6.9 23.9 2.9 6.5 16.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3595) DUF2868 PF11067.3 CDI84808.1 - 2.8 6.9 26.0 4.2 6.4 18.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2868) PAT1 PF09770.4 CDI84808.1 - 4.4 5.4 77.9 5.3 5.1 54.0 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Asp-B-Hydro_N PF05279.6 CDI84808.1 - 6 6.6 28.7 6.9 6.4 19.9 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Na_trans_assoc PF06512.8 CDI84808.1 - 6.1 6.7 25.1 8.4 6.2 17.4 1.2 1 0 0 1 1 1 0 Sodium ion transport-associated DUF966 PF06136.8 CDI84808.1 - 9 5.6 33.9 14 5.0 23.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Transglut_core3 PF13471.1 CDI84811.1 - 0.015 15.0 2.0 0.015 15.0 1.4 3.6 4 0 0 4 4 4 0 Transglutaminase-like superfamily Med15 PF09606.5 CDI84811.1 - 1.4 7.0 82.6 2.1 6.4 57.2 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal SR-25 PF10500.4 CDI84811.1 - 1.6 8.1 42.0 0.11 11.9 18.8 2.1 1 1 1 2 2 2 0 Nuclear RNA-splicing-associated protein PAT1 PF09770.4 CDI84811.1 - 2.8 6.0 73.8 3.4 5.7 51.2 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Syja_N PF02383.13 CDI84814.1 - 5.6e-10 38.4 0.0 5.6e-10 38.4 0.0 4.3 2 2 1 3 3 3 1 SacI homology domain Ribosomal_60s PF00428.14 CDI84814.1 - 3.2e-06 27.4 22.5 0.0001 22.5 4.1 2.7 2 0 0 2 2 2 2 60s Acidic ribosomal protein LMBR1 PF04791.11 CDI84814.1 - 4.8e-05 22.1 3.2 4.8e-05 22.1 2.2 2.6 3 0 0 3 3 3 1 LMBR1-like membrane protein Med15 PF09606.5 CDI84814.1 - 0.00023 19.5 5.3 0.00023 19.5 3.7 3.7 3 1 1 4 4 4 2 ARC105 or Med15 subunit of Mediator complex non-fungal Spt20 PF12090.3 CDI84814.1 - 0.013 14.8 0.6 0.013 14.8 0.4 6.3 3 2 1 4 4 4 0 Spt20 family Coiled PF05710.7 CDI84814.1 - 0.019 15.4 15.2 0.019 15.4 10.5 2.5 2 0 0 2 2 2 0 Coiled coil DUF572 PF04502.8 CDI84814.1 - 0.11 11.6 57.5 0.45 9.6 5.1 3.3 3 0 0 3 3 3 0 Family of unknown function (DUF572) Rifin_STEVOR PF02009.11 CDI84815.1 - 0.43 10.1 7.5 0.46 10.0 5.2 1.2 1 0 0 1 1 1 0 Rifin/stevor family Bac_luciferase PF00296.15 CDI84815.1 - 5.8 5.9 21.9 0.79 8.7 1.9 2.1 2 0 0 2 2 2 0 Luciferase-like monooxygenase CDK2AP PF09806.4 CDI84816.1 - 0.00017 21.9 12.9 0.00017 21.9 9.0 5.6 4 1 0 4 4 4 1 Cyclin-dependent kinase 2-associated protein SR-25 PF10500.4 CDI84816.1 - 0.0074 15.7 12.4 0.0074 15.7 8.6 7.3 6 2 0 7 7 7 4 Nuclear RNA-splicing-associated protein Pkinase PF00069.20 CDI84818.1 - 1.1e-09 37.8 0.0 1.2e-08 34.4 0.0 2.3 2 0 0 2 2 2 1 Protein kinase domain Kinase-like PF14531.1 CDI84818.1 - 5.4e-08 32.1 0.0 3.6e-06 26.1 0.0 2.3 1 1 0 1 1 1 1 Kinase-like Pkinase_Tyr PF07714.12 CDI84818.1 - 1.8e-05 23.9 0.0 4.3e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase Corona_nucleoca PF00937.13 CDI84819.1 - 3.6 6.4 32.8 0.048 12.6 15.8 2.0 2 0 0 2 2 2 0 Coronavirus nucleocapsid protein SelP_N PF04592.9 CDI84819.1 - 4.7 6.5 13.2 6.8 6.0 9.2 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Suf PF05843.9 CDI84819.1 - 6.6 6.3 20.4 0.88 9.2 11.4 1.4 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) 7TM_GPCR_Srv PF10323.4 CDI84820.1 - 0.046 12.8 0.8 3.2 6.7 0.2 2.1 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srv DUF572 PF04502.8 CDI84820.1 - 0.16 11.1 11.2 0.2 10.8 7.8 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) NinG PF05766.7 CDI84820.1 - 0.4 10.3 8.3 2 8.1 1.2 2.2 2 0 0 2 2 2 0 Bacteriophage Lambda NinG protein DUF4407 PF14362.1 CDI84820.1 - 0.42 9.5 22.3 0.5 9.2 15.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Citrate_synt PF00285.16 CDI84820.1 - 0.48 9.0 6.2 0.59 8.8 4.3 1.1 1 0 0 1 1 1 0 Citrate synthase DUF966 PF06136.8 CDI84820.1 - 0.74 9.1 7.1 0.95 8.8 4.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) DUF935 PF06074.7 CDI84820.1 - 0.97 8.0 19.5 1.3 7.6 13.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF935) RAB3GAP2_N PF14655.1 CDI84820.1 - 1.1 8.1 7.6 0.1 11.5 0.7 2.1 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus 7TM_transglut PF14402.1 CDI84820.1 - 1.4 7.7 3.4 0.41 9.5 0.3 1.5 2 0 0 2 2 2 0 7 transmembrane helices usually fused to an inactive transglutaminase DUF4045 PF13254.1 CDI84820.1 - 1.6 7.9 8.9 2 7.5 6.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) PLRV_ORF5 PF01690.12 CDI84820.1 - 3.4 6.7 9.3 4 6.4 6.5 1.0 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein DUF4570 PF15134.1 CDI84820.1 - 6.9 6.5 15.2 1.6 8.6 3.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4570) Peptidase_S64 PF08192.6 CDI84820.1 - 7.4 4.7 7.4 8.8 4.5 5.1 1.1 1 0 0 1 1 1 0 Peptidase family S64 E1-E2_ATPase PF00122.15 CDI84821.1 - 9.4e-21 73.8 18.7 7.3e-20 70.9 13.0 2.5 1 1 0 1 1 1 1 E1-E2 ATPase DUF3332 PF11810.3 CDI84821.1 - 0.00011 21.9 17.8 0.00017 21.3 12.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3332) Rtf2 PF04641.7 CDI84821.1 - 0.00038 19.7 14.7 0.00042 19.6 10.2 1.2 1 0 0 1 1 1 1 Rtf2 RING-finger AAA_23 PF13476.1 CDI84821.1 - 0.02 15.2 31.8 0.027 14.8 22.1 1.3 1 0 0 1 1 1 0 AAA domain Senescence_reg PF04520.8 CDI84821.1 - 0.067 13.6 12.7 0.093 13.2 8.8 1.2 1 0 0 1 1 1 0 Senescence regulator Presenilin PF01080.12 CDI84821.1 - 0.093 11.5 10.4 0.14 10.9 7.2 1.2 1 0 0 1 1 1 0 Presenilin DUF2201_N PF13203.1 CDI84821.1 - 0.1 11.7 32.9 0.19 10.8 22.8 1.5 1 1 0 1 1 1 0 Putative metallopeptidase domain SAGA-Tad1 PF12767.2 CDI84821.1 - 0.14 11.7 28.7 0.18 11.4 19.9 1.1 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit SPX PF03105.14 CDI84821.1 - 0.19 11.4 21.1 0.23 11.1 14.6 1.1 1 0 0 1 1 1 0 SPX domain Med15 PF09606.5 CDI84821.1 - 0.61 8.2 82.1 0.73 7.9 56.9 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Zip PF02535.17 CDI84821.1 - 0.65 8.9 3.7 0.93 8.4 2.5 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter DDHD PF02862.12 CDI84821.1 - 0.87 9.3 20.3 1.4 8.6 14.1 1.3 1 0 0 1 1 1 0 DDHD domain PLRV_ORF5 PF01690.12 CDI84821.1 - 0.91 8.6 22.8 1.1 8.2 15.8 1.0 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein PAT1 PF09770.4 CDI84821.1 - 1.1 7.4 65.5 1.4 7.1 45.4 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Borrelia_P83 PF05262.6 CDI84821.1 - 1.2 7.2 30.9 1.4 7.1 21.4 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF342 PF03961.8 CDI84821.1 - 1.5 7.1 18.8 2.6 6.3 13.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF4045 PF13254.1 CDI84821.1 - 1.7 7.8 21.7 2.2 7.4 15.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) DUF4638 PF15472.1 CDI84821.1 - 2 7.9 18.9 3.3 7.2 13.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) TFIIA PF03153.8 CDI84821.1 - 2.1 8.1 43.3 2.9 7.6 30.0 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Asp-B-Hydro_N PF05279.6 CDI84821.1 - 4.1 7.1 24.2 5.8 6.6 16.8 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region F-protein PF00469.15 CDI84821.1 - 4.5 6.5 23.2 8.2 5.7 16.1 1.4 1 0 0 1 1 1 0 Negative factor, (F-Protein) or Nef FLO_LFY PF01698.11 CDI84821.1 - 5.1 5.8 22.2 8.4 5.1 15.4 1.3 1 0 0 1 1 1 0 Floricaula / Leafy protein GAGA_bind PF06217.7 CDI84821.1 - 5.7 6.8 27.5 7.8 6.3 19.0 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family SAPS PF04499.10 CDI84821.1 - 6.2 5.3 24.0 8 4.9 16.6 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein FAM60A PF15396.1 CDI84821.1 - 6.4 6.4 24.5 9.7 5.8 17.0 1.2 1 0 0 1 1 1 0 Protein Family FAM60A HlyD_2 PF12700.2 CDI84821.1 - 6.8 5.7 28.2 9.3 5.2 19.6 1.2 1 0 0 1 1 1 0 HlyD family secretion protein Neur_chan_memb PF02932.11 CDI84821.1 - 7.3 6.4 22.5 4.8 6.9 14.2 1.6 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region GPCR_chapero_1 PF11904.3 CDI84821.1 - 9.2 5.3 25.1 13 4.8 17.4 1.2 1 0 0 1 1 1 0 GPCR-chaperone DUF1635 PF07795.6 CDI84822.1 - 0.056 12.8 0.3 0.072 12.4 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) SR-25 PF10500.4 CDI84822.1 - 0.059 12.8 13.3 0.11 12.0 9.2 1.5 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF4614 PF15391.1 CDI84822.1 - 0.33 10.7 13.2 0.64 9.7 9.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) Hid1 PF12722.2 CDI84822.1 - 0.69 7.5 5.0 0.84 7.2 3.5 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Corona_nucleoca PF00937.13 CDI84822.1 - 1.1 8.1 13.4 1.6 7.6 9.3 1.2 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein Macoilin PF09726.4 CDI84822.1 - 1.8 6.7 17.8 2.8 6.1 12.3 1.2 1 0 0 1 1 1 0 Transmembrane protein Sec3_C PF09763.4 CDI84822.1 - 4.5 5.2 6.6 5.4 5.0 4.6 1.0 1 0 0 1 1 1 0 Exocyst complex component Sec3 TFIIF_alpha PF05793.7 CDI84822.1 - 8.7 4.5 12.4 11 4.3 8.6 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) CAF-1_p150 PF11600.3 CDI84823.1 - 0.0069 15.7 26.0 0.0091 15.3 18.0 1.1 1 0 0 1 1 1 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal SprA-related PF12118.3 CDI84823.1 - 0.013 14.8 41.4 0.018 14.3 28.7 1.2 1 0 0 1 1 1 0 SprA-related family DUF1645 PF07816.6 CDI84823.1 - 0.027 14.9 23.8 0.035 14.5 16.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1645) RR_TM4-6 PF06459.7 CDI84823.1 - 0.046 13.5 15.1 0.052 13.4 10.5 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Med15 PF09606.5 CDI84823.1 - 0.077 11.1 47.3 0.086 11.0 32.8 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal PAT1 PF09770.4 CDI84823.1 - 0.089 11.0 37.5 0.1 10.8 26.0 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 AAA_23 PF13476.1 CDI84823.1 - 0.13 12.5 10.6 0.15 12.3 7.4 1.1 1 0 0 1 1 1 0 AAA domain DUF605 PF04652.11 CDI84823.1 - 0.14 11.5 34.0 0.15 11.4 23.5 1.0 1 0 0 1 1 1 0 Vta1 like Borrelia_P83 PF05262.6 CDI84823.1 - 0.19 9.9 14.4 0.18 10.0 10.0 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein SAGA-Tad1 PF12767.2 CDI84823.1 - 0.41 10.2 26.3 0.48 10.0 18.2 1.1 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit SOBP PF15279.1 CDI84823.1 - 0.42 10.9 24.6 0.5 10.7 17.1 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein TFIIA PF03153.8 CDI84823.1 - 0.46 10.3 36.4 0.53 10.1 25.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Hex_IIIa PF02455.11 CDI84823.1 - 0.6 8.7 17.2 0.67 8.5 11.9 1.0 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) Raftlin PF15250.1 CDI84823.1 - 0.63 8.4 16.3 0.73 8.2 11.3 1.1 1 0 0 1 1 1 0 Raftlin ATG16 PF08614.6 CDI84823.1 - 0.69 9.7 23.8 0.84 9.4 16.5 1.3 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Corona_nucleoca PF00937.13 CDI84823.1 - 0.73 8.7 28.0 0.87 8.4 19.4 1.2 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein LpxB PF02684.10 CDI84823.1 - 0.89 8.1 6.2 1.3 7.6 4.3 1.2 1 0 0 1 1 1 0 Lipid-A-disaccharide synthetase RAP1 PF07218.6 CDI84823.1 - 0.96 7.4 8.6 0.91 7.5 5.9 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) IncA PF04156.9 CDI84823.1 - 1.5 8.4 21.1 1.8 8.1 14.7 1.2 1 0 0 1 1 1 0 IncA protein NARP1 PF12569.3 CDI84823.1 - 1.5 7.4 14.4 1.9 7.1 10.0 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Herpes_TAF50 PF03326.8 CDI84823.1 - 1.7 7.5 32.7 1.9 7.3 22.7 1.0 1 0 0 1 1 1 0 Herpesvirus transcription activation factor (transactivator) APG6 PF04111.7 CDI84823.1 - 1.8 7.5 16.7 2 7.3 11.6 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Peptidase_S15 PF02129.13 CDI84823.1 - 2 7.7 12.9 2.6 7.3 8.9 1.1 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Activator_LAG-3 PF11498.3 CDI84823.1 - 2.2 6.9 47.3 2.8 6.5 32.8 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 GvpL_GvpF PF06386.6 CDI84823.1 - 2.4 7.6 13.9 3.1 7.3 9.6 1.2 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF VID27 PF08553.5 CDI84823.1 - 2.8 6.0 12.1 52 1.8 9.1 1.9 2 0 0 2 2 2 0 VID27 cytoplasmic protein RED_N PF07808.8 CDI84823.1 - 3.2 6.9 18.4 5.3 6.1 12.7 1.5 1 0 0 1 1 1 0 RED-like protein N-terminal region V_ATPase_I PF01496.14 CDI84823.1 - 3.5 5.3 9.1 3.7 5.2 6.3 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family eIF-3_zeta PF05091.7 CDI84823.1 - 4.1 5.9 20.1 4.4 5.8 13.9 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) FLO_LFY PF01698.11 CDI84823.1 - 4.4 6.0 15.5 4.9 5.8 10.7 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein Ycf1 PF05758.7 CDI84823.1 - 5 4.7 13.2 5.3 4.6 9.1 1.0 1 0 0 1 1 1 0 Ycf1 DUF572 PF04502.8 CDI84823.1 - 6.8 5.8 23.8 8.4 5.5 16.5 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF4175 PF13779.1 CDI84823.1 - 8.3 3.9 42.4 10 3.6 29.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) CDK5_activator PF03261.10 CDI84823.1 - 8.6 5.5 19.2 11 5.2 13.3 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein SAPS PF04499.10 CDI84824.1 - 0.043 12.4 18.5 0.043 12.4 12.8 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF572 PF04502.8 CDI84824.1 - 0.098 11.8 22.5 0.11 11.6 15.6 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) HlyD_2 PF12700.2 CDI84824.1 - 0.24 10.5 23.3 0.24 10.5 16.2 1.1 1 0 0 1 1 1 0 HlyD family secretion protein DUF4045 PF13254.1 CDI84824.1 - 0.9 8.7 29.1 0.97 8.6 20.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Med15 PF09606.5 CDI84824.1 - 2.1 6.4 86.4 2.5 6.2 59.9 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Amidohydro_2 PF04909.9 CDI84824.1 - 2.9 7.3 7.5 3.5 7.1 4.9 1.4 1 1 0 1 1 1 0 Amidohydrolase Utp14 PF04615.8 CDI84824.1 - 3.9 5.5 33.4 4.6 5.2 23.2 1.0 1 0 0 1 1 1 0 Utp14 protein Hid1 PF12722.2 CDI84824.1 - 5 4.6 30.6 5.5 4.5 21.2 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SAGA-Tad1 PF12767.2 CDI84824.1 - 6.5 6.3 30.4 8.9 5.8 21.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit LMBR1 PF04791.11 CDI84824.1 - 6.8 5.1 13.2 7.9 4.9 9.1 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein MRP-S26 PF14943.1 CDI84825.1 - 0.025 14.1 21.6 0.029 13.9 15.0 1.0 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 SR-25 PF10500.4 CDI84825.1 - 0.049 13.0 32.0 0.06 12.8 22.2 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF4643 PF15485.1 CDI84825.1 - 0.66 9.4 19.2 0.78 9.1 13.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4643) Rtf2 PF04641.7 CDI84825.1 - 2.3 7.3 21.5 2.7 7.1 14.9 1.0 1 0 0 1 1 1 0 Rtf2 RING-finger YhzD PF14120.1 CDI84825.1 - 2.6 8.0 4.2 0.57 10.1 0.5 1.7 2 0 0 2 2 2 0 YhzD-like protein RED_N PF07808.8 CDI84825.1 - 3.6 6.7 30.0 5 6.2 20.8 1.2 1 0 0 1 1 1 0 RED-like protein N-terminal region Dehydrin PF00257.14 CDI84826.1 - 5.4e-06 26.8 0.0 0.00016 22.0 0.0 2.2 1 1 0 1 1 1 1 Dehydrin TSA PF03249.8 CDI84826.1 - 0.022 13.3 8.9 0.043 12.3 6.2 1.5 1 0 0 1 1 1 0 Type specific antigen DUF4316 PF14195.1 CDI84826.1 - 0.088 12.8 0.7 0.17 11.9 0.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4316) DUF2731 PF10806.3 CDI84826.1 - 0.16 12.2 1.9 0.36 11.0 1.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2731) Neur_chan_memb PF02932.11 CDI84826.1 - 1.9 8.3 8.7 2.5 7.9 1.5 2.1 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region DUF2681 PF10883.3 CDI84826.1 - 2 8.6 11.6 26 5.0 0.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) Apt1 PF10351.4 CDI84826.1 - 4.7 5.9 13.4 2.3 6.9 6.8 1.9 2 0 0 2 2 2 0 Golgi-body localisation protein domain Pro_isomerase PF00160.16 CDI84828.1 - 4e-21 75.8 5.2 4e-21 75.8 3.6 1.9 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD AAA_23 PF13476.1 CDI84828.1 - 1.8e-05 25.1 23.7 0.0008 19.7 4.6 2.2 2 0 0 2 2 2 2 AAA domain BAF1_ABF1 PF04684.8 CDI84828.1 - 0.00019 20.4 19.2 0.00019 20.4 13.3 3.0 2 1 0 2 2 1 1 BAF1 / ABF1 chromatin reorganising factor DDHD PF02862.12 CDI84828.1 - 0.0027 17.5 20.0 0.036 13.8 1.5 2.1 2 0 0 2 2 2 2 DDHD domain AAA_11 PF13086.1 CDI84828.1 - 0.0032 17.0 20.5 0.054 13.0 1.1 2.2 2 0 0 2 2 2 2 AAA domain FLO_LFY PF01698.11 CDI84828.1 - 0.0087 14.9 20.6 0.053 12.3 0.8 2.1 2 0 0 2 2 2 2 Floricaula / Leafy protein RIC3 PF15361.1 CDI84828.1 - 0.013 15.7 2.5 0.013 15.7 1.7 2.4 2 0 0 2 2 2 0 Resistance to inhibitors of cholinesterase homologue 3 GAGA_bind PF06217.7 CDI84828.1 - 0.024 14.6 20.9 0.054 13.4 0.7 2.2 2 0 0 2 2 2 0 GAGA binding protein-like family Zip PF02535.17 CDI84828.1 - 0.024 13.6 6.0 1.6 7.6 2.2 2.1 2 0 0 2 2 2 0 ZIP Zinc transporter Gti1_Pac2 PF09729.4 CDI84828.1 - 0.025 14.4 0.8 0.025 14.4 0.6 2.2 2 0 0 2 2 2 0 Gti1/Pac2 family DUF1800 PF08811.6 CDI84828.1 - 0.035 13.0 28.6 0.03 13.2 3.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1800) Dynamin_N PF00350.18 CDI84828.1 - 0.048 13.4 14.0 0.09 12.5 0.4 2.3 2 0 0 2 2 2 0 Dynamin family Baculo_PP31 PF05311.6 CDI84828.1 - 0.052 12.8 25.5 0.18 11.0 3.6 2.1 2 0 0 2 2 2 0 Baculovirus 33KDa late protein (PP31) DUF4163 PF13739.1 CDI84828.1 - 0.065 14.0 0.4 0.065 14.0 0.3 2.3 2 0 0 2 2 1 0 Domain of unknown function (DUF4163) AUX_IAA PF02309.11 CDI84828.1 - 0.084 12.6 21.1 0.43 10.2 5.3 2.2 2 0 0 2 2 2 0 AUX/IAA family YABBY PF04690.8 CDI84828.1 - 0.28 11.4 18.2 1 9.5 4.8 2.2 2 0 0 2 2 2 0 YABBY protein Pex14_N PF04695.8 CDI84828.1 - 0.32 11.0 53.3 0.055 13.5 11.8 2.4 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Serinc PF03348.10 CDI84828.1 - 0.47 9.1 26.2 0.074 11.7 2.7 2.2 2 0 0 2 2 2 0 Serine incorporator (Serinc) MRP-S31 PF15433.1 CDI84828.1 - 0.5 9.7 31.8 0.088 12.2 5.1 2.2 2 0 0 2 2 2 0 Mitochondrial 28S ribosomal protein S31 DUF1266 PF06889.6 CDI84828.1 - 1.1 9.0 18.6 1.9 8.2 2.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1266) Herpes_DNAp_acc PF04929.7 CDI84828.1 - 1.5 7.6 19.0 0.65 8.9 5.2 2.1 2 0 0 2 2 2 0 Herpes DNA replication accessory factor Spore_coat_CotO PF14153.1 CDI84828.1 - 1.6 8.1 45.4 0.21 11.0 8.5 2.3 2 0 0 2 2 2 0 Spore coat protein CotO Afaf PF15339.1 CDI84828.1 - 1.9 8.0 14.5 5.8 6.4 5.0 2.2 2 0 0 2 2 2 0 Acrosome formation-associated factor Cellulose_synt PF03552.9 CDI84828.1 - 2.2 6.4 14.9 0.31 9.2 3.2 2.0 2 0 0 2 2 2 0 Cellulose synthase Tim54 PF11711.3 CDI84828.1 - 2.2 6.7 19.5 0.78 8.2 1.6 2.2 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 Rxt3 PF08642.5 CDI84828.1 - 2.8 8.1 17.4 6.2 7.0 3.4 2.6 3 0 0 3 3 2 0 Histone deacetylation protein Rxt3 SPX PF03105.14 CDI84828.1 - 3.2 7.4 24.9 0.7 9.6 2.9 2.1 2 0 0 2 2 2 0 SPX domain FNIP_N PF14636.1 CDI84828.1 - 3.5 8.1 29.4 3.1 8.2 8.9 2.5 2 0 0 2 2 2 0 Folliculin-interacting protein N-terminus DUF1980 PF09323.5 CDI84828.1 - 3.5 7.3 23.1 1.3 8.7 2.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) CPSF100_C PF13299.1 CDI84828.1 - 4 7.6 27.2 0.73 10.0 3.2 2.3 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal SprA-related PF12118.3 CDI84828.1 - 4.2 6.6 76.3 0.064 12.5 23.5 2.3 3 0 0 3 3 2 0 SprA-related family Band_3_cyto PF07565.8 CDI84828.1 - 4.4 6.7 33.2 0.063 12.7 3.1 2.2 2 0 0 2 2 2 0 Band 3 cytoplasmic domain UPF0560 PF10577.4 CDI84828.1 - 4.5 5.4 46.1 0.2 9.8 7.7 2.1 2 0 0 2 2 2 0 Uncharacterised protein family UPF0560 SID-1_RNA_chan PF13965.1 CDI84828.1 - 5.8 4.9 17.7 0.14 10.3 0.7 2.1 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 Peptidase_U57 PF05582.7 CDI84828.1 - 6 5.7 26.1 0.2 10.6 2.3 2.2 2 0 0 2 2 2 0 YabG peptidase U57 CKAP2_C PF15297.1 CDI84828.1 - 6.5 5.4 30.7 0.55 8.9 3.6 2.1 2 0 0 2 2 2 0 Cytoskeleton-associated protein 2 C-terminus CDC45 PF02724.9 CDI84828.1 - 6.9 4.5 25.1 2.3 6.1 7.2 2.1 2 0 0 2 2 2 0 CDC45-like protein Peptidase_S49_N PF08496.5 CDI84828.1 - 6.9 6.4 32.2 0.026 14.3 2.7 2.2 2 0 0 2 2 2 0 Peptidase family S49 N-terminal zf-C3HC4_3 PF13920.1 CDI84829.1 - 0.00036 20.1 10.1 0.00059 19.4 7.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CDI84829.1 - 0.0027 17.6 10.7 0.0047 16.9 7.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CDI84829.1 - 0.042 13.5 10.4 0.075 12.7 7.2 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) EMP24_GP25L PF01105.19 CDI84830.1 - 1.2e-27 96.8 0.3 1.4e-27 96.5 0.2 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Methyltransf_16 PF10294.4 CDI84831.1 - 1.1e-08 34.7 0.0 0.00056 19.4 0.0 2.1 2 0 0 2 2 2 2 Putative methyltransferase Methyltransf_18 PF12847.2 CDI84831.1 - 1.3e-05 25.7 0.0 4.7e-05 23.9 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 CDI84831.1 - 1.5e-05 24.3 0.0 2.5e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.9 CDI84831.1 - 2e-05 24.0 0.0 4.3e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_11 PF08241.7 CDI84831.1 - 0.004 17.5 0.0 0.045 14.2 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 CDI84831.1 - 0.0045 16.7 0.0 0.013 15.2 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CDI84831.1 - 0.0051 17.1 0.0 0.019 15.3 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 CDI84831.1 - 0.0059 16.6 0.0 0.0099 15.8 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.10 CDI84831.1 - 0.029 13.7 0.0 0.047 13.0 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 TehB PF03848.9 CDI84831.1 - 0.036 13.2 0.0 0.058 12.5 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB Methyltransf_31 PF13847.1 CDI84831.1 - 0.08 12.5 0.0 0.3 10.6 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_12 PF08242.7 CDI84831.1 - 0.13 12.7 0.0 0.56 10.7 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain Toxin_6 PF05453.7 CDI84831.1 - 0.21 11.8 1.5 0.41 10.9 1.1 1.4 1 0 0 1 1 1 0 BmTXKS1/BmP02 toxin family DUF3138 PF11336.3 CDI84832.1 - 4.3 5.4 10.7 5.6 5.0 7.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) MIP-T3 PF10243.4 CDI84833.1 - 0.19 10.1 68.2 0.19 10.1 47.3 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Utp14 PF04615.8 CDI84833.1 - 5.3 5.0 70.2 6.1 4.8 48.6 1.1 1 0 0 1 1 1 0 Utp14 protein Daxx PF03344.10 CDI84833.1 - 8.3 4.7 56.1 9.1 4.6 38.9 1.0 1 0 0 1 1 1 0 Daxx Family PAT1 PF09770.4 CDI84833.1 - 8.8 4.4 115.6 10 4.1 80.1 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Mqo PF06039.10 CDI84835.1 - 0.034 12.3 0.0 0.042 12.0 0.0 1.1 1 0 0 1 1 1 0 Malate:quinone oxidoreductase (Mqo) PAN_4 PF14295.1 CDI84837.1 - 2.9e-07 30.0 0.8 2.9e-07 30.0 0.6 2.1 2 0 0 2 2 2 1 PAN domain SseC PF04888.7 CDI84837.1 - 2.6e-05 23.6 8.9 2.6e-05 23.6 6.2 5.9 3 2 1 5 5 5 1 Secretion system effector C (SseC) like family ABC2_membrane_2 PF12679.2 CDI84837.1 - 9.8 4.9 11.6 0.79 8.5 0.9 2.8 3 0 0 3 3 3 0 ABC-2 family transporter protein Nha1_C PF08619.5 CDI84838.1 - 0.33 10.1 33.9 0.39 9.9 23.5 1.0 1 0 0 1 1 1 0 Alkali metal cation/H+ antiporter Nha1 C terminus Utp14 PF04615.8 CDI84838.1 - 0.54 8.3 42.8 0.58 8.2 29.6 1.0 1 0 0 1 1 1 0 Utp14 protein DUF4045 PF13254.1 CDI84838.1 - 1 8.5 33.4 1.1 8.4 23.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) AUX_IAA PF02309.11 CDI84838.1 - 1.2 8.8 31.7 1.7 8.3 22.0 1.2 1 0 0 1 1 1 0 AUX/IAA family DUF1510 PF07423.6 CDI84838.1 - 1.8 7.8 43.1 2.3 7.5 29.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Herpes_env PF01673.13 CDI84838.1 - 1.9 6.9 25.9 2.6 6.4 18.0 1.2 1 0 0 1 1 1 0 Herpesvirus putative major envelope glycoprotein Hid1 PF12722.2 CDI84838.1 - 2.4 5.7 40.5 2.6 5.5 28.1 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein FAM60A PF15396.1 CDI84838.1 - 2.7 7.7 35.1 3 7.5 24.3 1.1 1 0 0 1 1 1 0 Protein Family FAM60A PAT1 PF09770.4 CDI84838.1 - 2.8 6.0 88.2 2.9 6.0 61.2 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Raftlin PF15250.1 CDI84838.1 - 3.2 6.1 34.5 3.8 5.9 23.9 1.1 1 0 0 1 1 1 0 Raftlin Neur_chan_memb PF02932.11 CDI84838.1 - 6.1 6.6 30.4 6.7 6.5 21.1 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region SAPS PF04499.10 CDI84838.1 - 6.6 5.2 35.4 7.4 5.0 24.5 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein CDC45 PF02724.9 CDI84838.1 - 9.1 4.1 38.9 11 3.8 26.9 1.0 1 0 0 1 1 1 0 CDC45-like protein MarC PF01914.12 CDI84840.1 - 0.034 13.2 0.0 0.034 13.2 0.0 3.6 3 0 0 3 3 3 0 MarC family integral membrane protein DDRGK PF09756.4 CDI84841.1 - 0.039 13.3 10.6 0.038 13.3 7.3 1.1 1 0 0 1 1 1 0 DDRGK domain Med15 PF09606.5 CDI84841.1 - 0.047 11.8 35.3 0.041 12.0 24.5 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal PAT1 PF09770.4 CDI84841.1 - 0.051 11.8 24.1 0.049 11.8 16.7 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF4557 PF15101.1 CDI84841.1 - 0.055 13.2 19.5 0.061 13.1 13.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) PcfJ PF14284.1 CDI84841.1 - 0.071 12.6 7.5 0.1 12.0 5.2 1.3 1 0 0 1 1 1 0 PcfJ-like protein DUF3373 PF11853.3 CDI84841.1 - 0.077 11.5 9.0 0.091 11.2 6.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) Spore_coat_CotO PF14153.1 CDI84841.1 - 0.099 12.0 13.4 0.1 12.0 9.3 1.2 1 0 0 1 1 1 0 Spore coat protein CotO FimP PF09766.4 CDI84841.1 - 0.11 11.5 20.5 0.14 11.2 14.2 1.1 1 0 0 1 1 1 0 Fms-interacting protein Serinc PF03348.10 CDI84841.1 - 0.13 10.9 10.0 0.13 10.9 6.9 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) IncA PF04156.9 CDI84841.1 - 0.14 11.7 19.4 0.14 11.7 13.4 1.1 1 0 0 1 1 1 0 IncA protein Bud13 PF09736.4 CDI84841.1 - 0.15 12.2 12.8 0.16 12.2 8.9 1.2 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex Peptidase_S49_N PF08496.5 CDI84841.1 - 0.23 11.2 8.3 0.29 10.9 5.7 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Suf PF05843.9 CDI84841.1 - 0.29 10.8 14.4 0.29 10.8 10.0 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) RR_TM4-6 PF06459.7 CDI84841.1 - 0.41 10.5 12.0 0.5 10.2 8.3 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Cwf_Cwc_15 PF04889.7 CDI84841.1 - 0.43 10.2 18.2 0.49 10.0 12.6 1.0 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein BRF1 PF07741.8 CDI84841.1 - 0.45 10.7 9.2 0.55 10.4 6.4 1.3 1 0 0 1 1 1 0 Brf1-like TBP-binding domain DUF4407 PF14362.1 CDI84841.1 - 0.54 9.1 10.8 0.53 9.1 7.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) BAF1_ABF1 PF04684.8 CDI84841.1 - 0.54 9.0 30.1 0.58 8.9 20.9 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Insulin PF00049.13 CDI84841.1 - 0.55 11.0 9.7 0.89 10.3 6.7 1.3 1 0 0 1 1 1 0 Insulin/IGF/Relaxin family DUF106 PF01956.11 CDI84841.1 - 0.61 9.6 7.5 0.59 9.6 5.2 1.1 1 0 0 1 1 1 0 Integral membrane protein DUF106 Activator_LAG-3 PF11498.3 CDI84841.1 - 0.62 8.7 38.4 0.71 8.5 26.6 1.3 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Peptidase_U57 PF05582.7 CDI84841.1 - 0.67 8.8 8.2 0.71 8.7 5.7 1.1 1 0 0 1 1 1 0 YabG peptidase U57 DUF4175 PF13779.1 CDI84841.1 - 0.68 7.5 33.1 0.69 7.5 23.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Sec62 PF03839.11 CDI84841.1 - 0.8 9.0 5.9 1 8.7 4.1 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 DUF4647 PF15504.1 CDI84841.1 - 0.8 8.4 20.4 0.85 8.4 14.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4647) SpoIIIAH PF12685.2 CDI84841.1 - 0.85 9.0 14.4 0.95 8.9 10.0 1.1 1 0 0 1 1 1 0 SpoIIIAH-like protein Peptidase_S15 PF02129.13 CDI84841.1 - 0.87 8.9 10.5 0.94 8.8 7.3 1.0 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) OATP PF03137.15 CDI84841.1 - 0.91 7.4 10.2 1.1 7.2 7.1 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family FCP1_C PF09309.5 CDI84841.1 - 1 8.6 17.5 1.5 8.1 12.1 1.3 1 0 0 1 1 1 0 FCP1, C-terminal Neur_chan_memb PF02932.11 CDI84841.1 - 1 9.1 12.7 1.2 9.0 8.8 1.0 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region CagX PF03524.10 CDI84841.1 - 1 8.5 8.4 1.2 8.3 5.8 1.1 1 0 0 1 1 1 0 Conjugal transfer protein Gag_spuma PF03276.9 CDI84841.1 - 1.1 7.4 23.5 1.1 7.5 16.3 1.1 1 0 0 1 1 1 0 Spumavirus gag protein DUF853 PF05872.7 CDI84841.1 - 1.2 7.4 8.8 1.1 7.4 6.1 1.0 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) eIF-3_zeta PF05091.7 CDI84841.1 - 1.4 7.4 15.9 1.5 7.3 11.0 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) OmpH PF03938.9 CDI84841.1 - 1.4 8.8 31.3 1.9 8.4 21.7 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Plasmodium_Vir PF05795.6 CDI84841.1 - 1.5 7.9 12.5 1.6 7.8 8.7 1.0 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Glyco_transf_15 PF01793.11 CDI84841.1 - 1.6 7.5 9.7 1.6 7.5 6.7 1.1 1 0 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase Spc7_N PF15402.1 CDI84841.1 - 1.7 6.5 26.1 1.9 6.3 18.1 1.0 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 Folate_carrier PF01770.13 CDI84841.1 - 1.7 7.0 7.6 1.8 6.9 5.2 1.1 1 0 0 1 1 1 0 Reduced folate carrier G0-G1_switch_2 PF15103.1 CDI84841.1 - 1.8 8.8 9.9 2.5 8.3 6.9 1.2 1 0 0 1 1 1 0 G0/G1 switch protein 2 VIT1 PF01988.14 CDI84841.1 - 1.9 7.9 5.0 2.5 7.5 3.4 1.2 1 0 0 1 1 1 0 VIT family zf-DHHC PF01529.15 CDI84841.1 - 2 7.8 6.5 2.5 7.4 4.5 1.3 1 0 0 1 1 1 0 DHHC palmitoyltransferase EIIBC-GUT_N PF03612.9 CDI84841.1 - 2.7 7.5 8.2 2.9 7.4 5.7 1.3 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus DUF2217 PF10265.4 CDI84841.1 - 2.8 6.5 17.8 3.2 6.4 12.4 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) FLO_LFY PF01698.11 CDI84841.1 - 4 6.2 13.1 3.8 6.2 9.1 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein DUF4220 PF13968.1 CDI84841.1 - 4.4 6.2 7.1 4.7 6.2 4.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4220) Dicty_REP PF05086.7 CDI84841.1 - 4.5 4.9 15.0 4.7 4.8 10.4 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein FHIPEP PF00771.15 CDI84841.1 - 4.7 5.4 6.6 4.8 5.3 4.6 1.1 1 0 0 1 1 1 0 FHIPEP family Lin-8 PF03353.10 CDI84841.1 - 4.7 6.3 16.8 5.1 6.2 11.7 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Macoilin PF09726.4 CDI84841.1 - 4.8 5.3 21.4 5.3 5.2 14.9 1.0 1 0 0 1 1 1 0 Transmembrane protein Cellulose_synt PF03552.9 CDI84841.1 - 5 5.2 5.6 4.8 5.3 3.9 1.0 1 0 0 1 1 1 0 Cellulose synthase Allexi_40kDa PF05549.6 CDI84841.1 - 5.1 6.3 11.5 5.6 6.1 7.9 1.1 1 0 0 1 1 1 0 Allexivirus 40kDa protein Endonuc_Holl PF10107.4 CDI84841.1 - 6.4 6.4 11.6 7.5 6.2 8.0 1.1 1 0 0 1 1 1 0 Endonuclease related to archaeal Holliday junction resolvase Paf1 PF03985.8 CDI84841.1 - 6.5 5.3 16.5 7 5.2 11.4 1.2 1 0 0 1 1 1 0 Paf1 DUF3260 PF11658.3 CDI84841.1 - 7 4.6 12.5 7.5 4.5 8.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3260) DUF4544 PF15077.1 CDI84841.1 - 7.8 5.9 9.5 8.4 5.8 6.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4544) TFIIA PF03153.8 CDI84841.1 - 8.3 6.1 26.2 9.1 6.0 18.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Borrelia_P83 PF05262.6 CDI84841.1 - 9.2 4.4 13.9 9.2 4.3 9.7 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Plasmodium_Vir PF05795.6 CDI84844.1 - 0.26 10.4 17.9 0.32 10.1 12.4 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein SAPS PF04499.10 CDI84844.1 - 0.27 9.8 23.8 0.32 9.5 16.5 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Ycf1 PF05758.7 CDI84844.1 - 0.27 8.9 17.0 0.28 8.8 11.8 1.0 1 0 0 1 1 1 0 Ycf1 DUF572 PF04502.8 CDI84844.1 - 0.35 10.0 25.1 0.41 9.8 17.4 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF572) RAP1 PF07218.6 CDI84844.1 - 0.47 8.4 15.4 0.58 8.1 10.7 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) GAGA_bind PF06217.7 CDI84844.1 - 0.55 10.1 21.9 0.63 9.9 15.2 1.0 1 0 0 1 1 1 0 GAGA binding protein-like family DUF2217 PF10265.4 CDI84844.1 - 0.57 8.8 22.1 0.63 8.7 15.3 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) DDRGK PF09756.4 CDI84844.1 - 0.67 9.3 24.9 0.85 9.0 17.2 1.1 1 0 0 1 1 1 0 DDRGK domain SLD3 PF08639.5 CDI84844.1 - 0.77 8.3 33.4 0.83 8.2 23.2 1.0 1 0 0 1 1 1 0 DNA replication regulator SLD3 Neur_chan_memb PF02932.11 CDI84844.1 - 1.4 8.7 19.3 1.6 8.5 13.4 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Spc7_N PF15402.1 CDI84844.1 - 1.8 6.4 27.3 2 6.3 18.9 1.1 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 Med15 PF09606.5 CDI84844.1 - 1.8 6.6 50.7 2 6.4 35.1 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Macoilin PF09726.4 CDI84844.1 - 2.6 6.1 31.0 3.6 5.7 21.5 1.2 1 0 0 1 1 1 0 Transmembrane protein Mem_trans PF03547.13 CDI84844.1 - 2.6 6.2 17.2 2.8 6.1 11.9 1.1 1 0 0 1 1 1 0 Membrane transport protein PAT1 PF09770.4 CDI84844.1 - 2.7 6.1 41.3 3.1 5.9 28.6 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 CDC45 PF02724.9 CDI84844.1 - 2.8 5.8 20.3 3.7 5.4 14.1 1.2 1 0 0 1 1 1 0 CDC45-like protein FAM60A PF15396.1 CDI84844.1 - 2.9 7.5 24.8 4.3 7.0 17.2 1.3 1 0 0 1 1 1 0 Protein Family FAM60A DUF4638 PF15472.1 CDI84844.1 - 3.6 7.1 20.4 4.3 6.8 14.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) DNA_pol_viral_N PF00242.12 CDI84844.1 - 4.2 6.2 31.7 4.9 6.0 22.0 1.0 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain DUF1510 PF07423.6 CDI84844.1 - 4.9 6.4 27.6 6 6.1 19.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Dicty_REP PF05086.7 CDI84844.1 - 5.4 4.6 22.0 6 4.4 15.2 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Rtf2 PF04641.7 CDI84844.1 - 5.7 6.0 24.5 8.4 5.5 17.0 1.3 1 0 0 1 1 1 0 Rtf2 RING-finger DUF2981 PF11200.3 CDI84844.1 - 6.1 5.8 6.6 6.8 5.6 4.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) UPF0561 PF10573.4 CDI84844.1 - 6.1 6.6 22.6 8.8 6.1 15.6 1.3 1 1 0 1 1 1 0 Uncharacterised protein family UPF0561 DUF3373 PF11853.3 CDI84844.1 - 6.8 5.0 14.2 8.1 4.8 9.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) Hid1 PF12722.2 CDI84844.1 - 6.9 4.2 29.3 8 3.9 20.3 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF2413 PF10310.4 CDI84844.1 - 7.2 5.3 27.3 8.9 5.0 18.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) Asp-B-Hydro_N PF05279.6 CDI84844.1 - 8.7 6.1 14.8 10 5.8 10.3 1.0 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region DUF4220 PF13968.1 CDI84844.1 - 8.8 5.3 11.5 10 5.0 8.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4220) FliP PF00813.15 CDI84844.1 - 9.2 5.9 8.8 11 5.6 6.1 1.2 1 0 0 1 1 1 0 FliP family Yip1 PF04893.12 CDI84845.1 - 0.14 11.6 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 Yip1 domain IncA PF04156.9 CDI84847.1 - 4.5e-07 29.6 18.7 5e-07 29.5 13.0 1.1 1 0 0 1 1 1 1 IncA protein HemX PF04375.9 CDI84847.1 - 0.0028 16.3 31.8 0.0032 16.1 22.0 1.1 1 0 0 1 1 1 1 HemX DUF4367 PF14285.1 CDI84847.1 - 0.0033 16.7 0.6 0.0052 16.1 0.4 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4367) Shadoo PF14999.1 CDI84847.1 - 0.012 15.4 2.4 0.018 14.8 1.7 1.3 1 0 0 1 1 1 0 Shadow of prion protein, neuroprotective SpoIIIAH PF12685.2 CDI84847.1 - 0.02 14.3 19.2 0.026 14.0 13.3 1.1 1 0 0 1 1 1 0 SpoIIIAH-like protein RNF111_N PF15303.1 CDI84847.1 - 0.02 14.4 22.4 0.024 14.1 15.5 1.1 1 0 0 1 1 1 0 E3 ubiquitin-protein ligase Arkadia N-terminus FHIPEP PF00771.15 CDI84847.1 - 0.02 13.2 10.2 0.024 12.9 7.1 1.2 1 0 0 1 1 1 0 FHIPEP family DUF4131 PF13567.1 CDI84847.1 - 0.072 12.4 3.0 0.095 12.1 2.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) DUF2217 PF10265.4 CDI84847.1 - 0.074 11.8 15.1 0.079 11.7 10.4 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) DUF2232 PF09991.4 CDI84847.1 - 0.081 11.9 8.9 0.095 11.6 6.1 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) DUF4603 PF15376.1 CDI84847.1 - 0.11 9.6 17.4 0.12 9.6 12.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) DUF4557 PF15101.1 CDI84847.1 - 0.12 12.2 27.4 0.15 11.8 19.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) FTCD_C PF04961.7 CDI84847.1 - 0.12 11.7 9.5 0.17 11.2 6.6 1.3 1 1 0 1 1 1 0 Formiminotransferase-cyclodeaminase Dehydrin PF00257.14 CDI84847.1 - 0.16 12.3 20.4 0.24 11.7 14.1 1.3 1 0 0 1 1 1 0 Dehydrin DUF4446 PF14584.1 CDI84847.1 - 0.17 11.7 8.4 0.2 11.4 5.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) Cwf_Cwc_15 PF04889.7 CDI84847.1 - 0.17 11.5 23.0 0.2 11.3 15.9 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF2215 PF10225.4 CDI84847.1 - 0.22 10.9 14.5 0.27 10.6 10.0 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) PMSI1 PF15322.1 CDI84847.1 - 0.25 10.3 21.2 0.28 10.2 14.7 1.0 1 0 0 1 1 1 0 Protein missing in infertile sperm 1, putative Gag_spuma PF03276.9 CDI84847.1 - 0.36 9.1 34.5 0.46 8.7 23.9 1.2 1 0 0 1 1 1 0 Spumavirus gag protein DUF3450 PF11932.3 CDI84847.1 - 0.38 9.9 34.2 0.4 9.9 23.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DDRGK PF09756.4 CDI84847.1 - 0.41 10.0 26.4 0.48 9.8 18.3 1.1 1 0 0 1 1 1 0 DDRGK domain Ycf1 PF05758.7 CDI84847.1 - 0.42 8.2 19.3 0.43 8.2 13.4 1.0 1 0 0 1 1 1 0 Ycf1 Folate_carrier PF01770.13 CDI84847.1 - 0.48 8.8 12.3 0.56 8.6 8.5 1.2 1 0 0 1 1 1 0 Reduced folate carrier Med15 PF09606.5 CDI84847.1 - 0.49 8.5 55.5 0.58 8.2 38.5 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF1510 PF07423.6 CDI84847.1 - 0.49 9.7 26.0 0.58 9.4 18.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) NABP PF07990.7 CDI84847.1 - 0.55 9.4 25.6 0.65 9.2 17.7 1.0 1 0 0 1 1 1 0 Nucleic acid binding protein NABP NARP1 PF12569.3 CDI84847.1 - 0.6 8.7 20.1 0.61 8.7 13.9 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 CoA_transf_3 PF02515.12 CDI84847.1 - 0.61 9.2 10.1 0.76 8.9 7.0 1.1 1 0 0 1 1 1 0 CoA-transferase family III FadA PF09403.5 CDI84847.1 - 0.78 9.7 17.2 0.93 9.5 12.0 1.1 1 0 0 1 1 1 0 Adhesion protein FadA DUF2072 PF09845.4 CDI84847.1 - 0.84 9.5 8.4 1 9.3 5.8 1.3 1 0 0 1 1 1 0 Zn-ribbon containing protein (DUF2072) Macoilin PF09726.4 CDI84847.1 - 0.93 7.6 20.8 1.1 7.4 14.4 1.1 1 0 0 1 1 1 0 Transmembrane protein CD20 PF04103.10 CDI84847.1 - 0.96 9.3 13.0 3.8 7.4 9.0 1.9 1 1 0 1 1 1 0 CD20-like family Herpes_glycop PF01528.11 CDI84847.1 - 0.98 8.0 4.7 1.2 7.7 3.2 1.3 1 0 0 1 1 1 0 Herpesvirus glycoprotein M TORC_M PF12885.2 CDI84847.1 - 0.99 9.1 16.9 1.2 8.8 11.7 1.2 1 0 0 1 1 1 0 Transducer of regulated CREB activity middle domain ADP_ribosyl_GH PF03747.9 CDI84847.1 - 1 9.0 6.3 1.2 8.7 4.4 1.2 1 0 0 1 1 1 0 ADP-ribosylglycohydrolase FPN1 PF06963.7 CDI84847.1 - 1.1 7.5 6.2 1.4 7.2 4.3 1.3 1 0 0 1 1 1 0 Ferroportin1 (FPN1) Spc7_N PF15402.1 CDI84847.1 - 1.1 7.1 26.8 1.2 7.0 18.6 1.0 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 DUF3373 PF11853.3 CDI84847.1 - 1.2 7.5 16.3 1.7 7.1 11.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) Cellulose_synt PF03552.9 CDI84847.1 - 1.4 7.1 11.3 1.5 7.0 7.8 1.0 1 0 0 1 1 1 0 Cellulose synthase MRP-S31 PF15433.1 CDI84847.1 - 1.4 8.2 23.9 1.7 8.0 16.5 1.1 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 AMP-binding PF00501.23 CDI84847.1 - 1.4 7.2 5.5 1.4 7.2 3.8 1.0 1 0 0 1 1 1 0 AMP-binding enzyme TMEM51 PF15345.1 CDI84847.1 - 1.5 8.4 22.6 2.2 7.9 15.7 1.3 1 0 0 1 1 1 0 Transmembrane protein 51 Asp-B-Hydro_N PF05279.6 CDI84847.1 - 1.5 8.5 15.7 1.7 8.4 10.9 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Serinc PF03348.10 CDI84847.1 - 1.5 7.4 17.6 1.8 7.2 12.2 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) GAGA_bind PF06217.7 CDI84847.1 - 1.5 8.6 21.0 1.7 8.5 14.6 1.0 1 0 0 1 1 1 0 GAGA binding protein-like family Peptidase_S15 PF02129.13 CDI84847.1 - 1.7 8.0 15.6 1.9 7.8 10.8 1.1 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Peptidase_S49_N PF08496.5 CDI84847.1 - 1.7 8.3 15.1 2.4 7.9 10.5 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Peptidase_U57 PF05582.7 CDI84847.1 - 1.8 7.4 16.0 2.1 7.2 11.1 1.1 1 0 0 1 1 1 0 YabG peptidase U57 Plasmodium_Vir PF05795.6 CDI84847.1 - 2 7.5 16.7 2.5 7.2 11.6 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Mem_trans PF03547.13 CDI84847.1 - 2 6.6 14.8 2.2 6.4 10.3 1.1 1 0 0 1 1 1 0 Membrane transport protein DUF3381 PF11861.3 CDI84847.1 - 2 7.9 19.3 2.3 7.6 13.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) PAT1 PF09770.4 CDI84847.1 - 2.1 6.5 46.5 2.3 6.3 32.2 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 PIH1 PF08190.7 CDI84847.1 - 2.2 7.6 25.8 2.4 7.5 17.9 1.0 1 0 0 1 1 1 0 pre-RNA processing PIH1/Nop17 DUF4045 PF13254.1 CDI84847.1 - 2.2 7.4 21.6 2.5 7.3 15.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Bud13 PF09736.4 CDI84847.1 - 2.4 8.4 27.1 3.1 8.0 18.8 1.2 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex K_trans PF02705.11 CDI84847.1 - 2.4 6.4 4.1 2.7 6.2 2.9 1.1 1 0 0 1 1 1 0 K+ potassium transporter eIF-3_zeta PF05091.7 CDI84847.1 - 3.1 6.3 24.9 3.4 6.1 17.3 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Raftlin PF15250.1 CDI84847.1 - 3.4 6.0 19.5 3.9 5.8 13.5 1.1 1 0 0 1 1 1 0 Raftlin CDC45 PF02724.9 CDI84847.1 - 3.5 5.5 21.9 3.9 5.4 15.2 1.1 1 0 0 1 1 1 0 CDC45-like protein ABC2_membrane_2 PF12679.2 CDI84847.1 - 3.5 6.4 5.3 4.2 6.1 3.7 1.3 1 0 0 1 1 1 0 ABC-2 family transporter protein Prog_receptor PF02161.10 CDI84847.1 - 3.6 6.3 19.4 5.5 5.7 13.5 1.3 1 0 0 1 1 1 0 Progesterone receptor YfhO PF09586.5 CDI84847.1 - 3.9 5.3 17.0 4.5 5.1 11.8 1.0 1 0 0 1 1 1 0 Bacterial membrane protein YfhO Pex16 PF08610.5 CDI84847.1 - 3.9 6.3 19.9 5.2 5.9 13.8 1.2 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) Spore_coat_CotO PF14153.1 CDI84847.1 - 3.9 6.8 28.6 5 6.5 19.8 1.2 1 0 0 1 1 1 0 Spore coat protein CotO Paf1 PF03985.8 CDI84847.1 - 4.1 6.0 26.2 4.9 5.7 18.2 1.1 1 0 0 1 1 1 0 Paf1 CbtA PF09490.5 CDI84847.1 - 4.3 6.5 10.7 5.6 6.2 7.4 1.1 1 0 0 1 1 1 0 Probable cobalt transporter subunit (CbtA) RR_TM4-6 PF06459.7 CDI84847.1 - 4.4 7.1 20.3 4.9 6.9 14.1 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Tim54 PF11711.3 CDI84847.1 - 4.6 5.7 16.1 5 5.6 11.2 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Tetraspannin PF00335.15 CDI84847.1 - 4.6 6.4 12.8 5.6 6.1 8.9 1.1 1 0 0 1 1 1 0 Tetraspanin family TT_ORF1 PF02956.9 CDI84847.1 - 5.2 5.4 20.0 6 5.1 13.9 1.0 1 0 0 1 1 1 0 TT viral orf 1 GBP_C PF02841.9 CDI84847.1 - 5.3 6.1 31.3 6.5 5.8 21.7 1.1 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain Bac_luciferase PF00296.15 CDI84847.1 - 5.8 5.9 8.4 7.3 5.6 5.8 1.2 1 0 0 1 1 1 0 Luciferase-like monooxygenase Dynamin_N PF00350.18 CDI84847.1 - 5.9 6.6 11.9 8.5 6.1 8.2 1.4 1 0 0 1 1 1 0 Dynamin family FLO_LFY PF01698.11 CDI84847.1 - 6 5.5 23.1 6.8 5.4 16.0 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein Sec62 PF03839.11 CDI84847.1 - 6.3 6.1 13.7 7.3 5.9 9.5 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 DUF3824 PF12868.2 CDI84847.1 - 6.8 7.6 20.3 17 6.3 14.0 1.6 1 1 0 1 1 1 0 Domain of unknwon function (DUF3824) APG6 PF04111.7 CDI84847.1 - 7.2 5.5 25.2 7.8 5.4 17.5 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Trp_oprn_chp PF09534.5 CDI84847.1 - 7.5 6.1 15.7 14 5.2 10.9 1.6 1 1 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) FAM60A PF15396.1 CDI84847.1 - 7.6 6.2 20.1 11 5.6 13.9 1.3 1 0 0 1 1 1 0 Protein Family FAM60A Herpes_DNAp_acc PF04929.7 CDI84847.1 - 7.6 5.3 18.8 8.9 5.1 13.1 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Muted PF14942.1 CDI84847.1 - 7.6 6.3 22.7 9.7 6.0 15.7 1.1 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein Dicty_REP PF05086.7 CDI84847.1 - 8.4 3.9 18.1 9.6 3.8 12.5 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein AUX_IAA PF02309.11 CDI84847.1 - 8.6 6.0 19.2 11 5.6 13.3 1.2 1 0 0 1 1 1 0 AUX/IAA family F-protein PF00469.15 CDI84847.1 - 9.7 5.4 15.9 12 5.1 11.1 1.3 1 0 0 1 1 1 0 Negative factor, (F-Protein) or Nef Afi1 PF07792.7 CDI84847.1 - 9.8 6.1 22.8 13 5.7 15.8 1.2 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Band_3_cyto PF07565.8 CDI84847.1 - 9.8 5.5 21.0 13 5.2 14.5 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Pkinase PF00069.20 CDI84848.1 - 0.051 12.7 0.0 0.074 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain DUF572 PF04502.8 CDI84849.1 - 0.0052 16.0 21.7 0.0057 15.9 15.0 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF572) RP-C_C PF11800.3 CDI84849.1 - 0.49 10.0 20.0 0.71 9.5 13.9 1.4 1 0 0 1 1 1 0 Replication protein C C-terminal region Hid1 PF12722.2 CDI84849.1 - 1.1 6.8 19.5 1.3 6.6 13.5 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein LMBR1 PF04791.11 CDI84849.1 - 1.5 7.2 6.2 1.8 7.0 4.3 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein DNA_pol_viral_N PF00242.12 CDI84849.1 - 9.1 5.1 17.8 11 4.9 12.3 1.1 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain SR-25 PF10500.4 CDI84850.1 - 0.004 16.6 25.7 0.004 16.6 17.8 4.3 1 1 2 4 4 4 1 Nuclear RNA-splicing-associated protein CAF-1_p150 PF11600.3 CDI84851.1 - 0.0033 16.8 30.7 0.0033 16.8 21.3 6.2 3 2 3 6 6 6 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal BRCT PF00533.21 CDI84852.1 - 0.0012 18.9 0.0 0.7 10.0 0.0 4.1 4 2 0 4 4 4 2 BRCA1 C Terminus (BRCT) domain TIP49 PF06068.8 CDI84853.1 - 1.1e-173 577.6 0.1 1.2e-173 577.3 0.1 1.0 1 0 0 1 1 1 1 TIP49 C-terminus AAA PF00004.24 CDI84853.1 - 6.2e-07 29.6 0.2 0.0042 17.2 0.1 2.6 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 CDI84853.1 - 0.00013 21.1 3.4 0.015 14.3 0.1 3.1 2 1 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_25 PF13481.1 CDI84853.1 - 0.0036 16.7 0.0 0.0082 15.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 CDI84853.1 - 0.011 15.8 0.1 0.64 10.1 0.0 2.6 2 1 0 2 2 2 0 AAA domain AAA_14 PF13173.1 CDI84853.1 - 0.019 14.8 0.0 1.4 8.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.1 CDI84853.1 - 0.027 14.4 1.2 0.71 9.8 0.0 2.8 2 1 0 2 2 2 0 AAA ATPase domain AAA_5 PF07728.9 CDI84853.1 - 0.064 12.9 0.1 5.2 6.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) UPF0079 PF02367.12 CDI84853.1 - 0.14 11.8 0.1 0.32 10.6 0.1 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 Macoilin PF09726.4 CDI84854.1 - 2.2e-05 23.0 16.8 2.2e-05 23.0 11.7 3.1 3 0 0 3 3 3 2 Transmembrane protein EphA2_TM PF14575.1 CDI84854.1 - 0.012 16.0 6.1 0.29 11.5 0.5 3.4 3 0 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain Spt20 PF12090.3 CDI84854.1 - 0.03 13.6 0.2 0.03 13.6 0.1 3.1 3 0 0 3 3 3 0 Spt20 family GRP PF07172.6 CDI84854.1 - 2.7 8.5 3.5 53 4.3 0.1 3.0 2 0 0 2 2 2 0 Glycine rich protein family CobT PF06213.7 CDI84855.1 - 0.0018 17.4 14.5 0.0023 17.1 3.1 2.1 2 0 0 2 2 2 2 Cobalamin biosynthesis protein CobT Pro_CA PF00484.14 CDI84855.1 - 0.42 10.6 4.8 0.42 10.5 0.3 2.4 3 0 0 3 3 3 0 Carbonic anhydrase Adaptin_binding PF10199.4 CDI84855.1 - 0.94 9.7 15.8 0.15 12.3 0.8 2.2 1 1 1 2 2 2 0 Alpha and gamma adaptin binding protein p34 DUF4614 PF15391.1 CDI84855.1 - 2.6 7.7 22.4 0.29 10.8 10.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4614) Apt1 PF10351.4 CDI84855.1 - 3 6.5 20.5 0.25 10.1 9.4 2.0 2 0 0 2 2 2 0 Golgi-body localisation protein domain BTV_NS2 PF04514.7 CDI84855.1 - 3.2 6.5 10.2 0.4 9.4 1.3 2.2 2 0 0 2 2 2 0 Bluetongue virus non-structural protein NS2 DUF1510 PF07423.6 CDI84855.1 - 4 6.7 17.8 6.3 6.1 5.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) SapB_1 PF05184.10 CDI84856.1 - 0.037 13.8 0.1 0.12 12.2 0.1 1.8 1 0 0 1 1 1 0 Saposin-like type B, region 1 Cyc-maltodext_C PF10438.4 CDI84857.1 - 0.12 12.4 2.6 1 9.4 0.0 3.2 2 1 1 3 3 3 0 Cyclo-malto-dextrinase C-terminal domain Fcf1 PF04900.7 CDI84858.1 - 2.6e-09 37.0 11.1 0.00022 21.2 0.0 3.8 4 0 0 4 4 4 2 Fcf1 IncA PF04156.9 CDI84858.1 - 0.00061 19.4 3.5 0.00061 19.4 2.5 2.4 2 0 0 2 2 2 1 IncA protein Otopetrin PF03189.8 CDI84859.1 - 9.8 5.0 7.7 39 3.0 5.3 1.9 1 1 0 1 1 1 0 Otopetrin AzlD PF05437.7 CDI84860.1 - 0.038 13.9 0.3 0.049 13.5 0.2 1.1 1 0 0 1 1 1 0 Branched-chain amino acid transport protein (AzlD) RskA PF10099.4 CDI84860.1 - 0.059 13.1 7.5 0.072 12.8 5.2 1.2 1 0 0 1 1 1 0 Anti-sigma-K factor rskA TrbI PF03743.9 CDI84860.1 - 0.064 12.7 5.0 0.074 12.5 3.4 1.2 1 0 0 1 1 1 0 Bacterial conjugation TrbI-like protein DUF533 PF04391.7 CDI84860.1 - 0.07 12.4 8.2 0.079 12.3 5.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF533) SR-25 PF10500.4 CDI84860.1 - 0.072 12.5 16.6 0.086 12.3 11.5 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein ACOX PF01756.14 CDI84860.1 - 0.1 11.9 4.4 0.13 11.6 3.0 1.1 1 0 0 1 1 1 0 Acyl-CoA oxidase CRISPR_Cse2 PF09485.5 CDI84860.1 - 0.13 12.3 3.4 0.15 12.0 2.4 1.3 1 0 0 1 1 1 0 CRISPR-associated protein Cse2 (CRISPR_cse2) Phage_sheath_1 PF04984.9 CDI84860.1 - 0.15 10.4 2.6 0.17 10.2 1.8 1.0 1 0 0 1 1 1 0 Phage tail sheath protein UPF0565 PF10561.4 CDI84860.1 - 0.17 10.7 2.9 0.21 10.4 2.0 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0565 Peptidase_S8 PF00082.17 CDI84860.1 - 0.18 10.9 9.0 0.21 10.6 6.2 1.0 1 0 0 1 1 1 0 Subtilase family DUF3357 PF11837.3 CDI84860.1 - 0.45 10.3 5.1 0.47 10.3 3.2 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF3357) Med3 PF11593.3 CDI84860.1 - 1.1 8.3 13.1 1.6 7.9 9.1 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Myco_19_kDa PF05481.7 CDI84860.1 - 1.4 8.7 17.6 0.12 12.2 8.8 1.7 1 1 1 2 2 2 0 Mycobacterium 19 kDa lipoprotein antigen LPP20 PF02169.11 CDI84860.1 - 1.5 8.9 8.4 2.1 8.5 5.8 1.2 1 0 0 1 1 1 0 LPP20 lipoprotein MSP1_C PF07462.6 CDI84860.1 - 3.4 5.9 8.0 3.8 5.7 5.5 1.0 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus TFIIA PF03153.8 CDI84860.1 - 5.8 6.7 8.8 5.9 6.6 6.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4139 PF13598.1 CDI84860.1 - 6.8 5.8 9.8 8.5 5.5 6.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4139) CAF-1_p150 PF11600.3 CDI84861.1 - 0.0012 18.3 41.0 0.0012 18.3 28.5 2.1 2 0 0 2 2 2 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal Glyco_transf_20 PF00982.16 CDI84862.1 - 8.9e-17 60.7 0.0 8.9e-17 60.7 0.0 3.0 2 1 1 3 3 3 2 Glycosyltransferase family 20 TFIIA PF03153.8 CDI84862.1 - 0.0011 18.9 25.1 0.0018 18.2 17.4 1.3 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit SprA-related PF12118.3 CDI84862.1 - 9.1 5.5 55.3 0.026 13.8 6.8 2.1 2 0 0 2 2 2 0 SprA-related family SR-25 PF10500.4 CDI84863.1 - 0.089 12.2 29.4 0.12 11.8 20.4 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein FAM60A PF15396.1 CDI84863.1 - 7 6.3 30.9 8 6.1 21.4 1.0 1 0 0 1 1 1 0 Protein Family FAM60A DUF2217 PF10265.4 CDI84866.1 - 0.032 12.9 33.5 0.042 12.6 23.2 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) SLD3 PF08639.5 CDI84866.1 - 0.2 10.2 42.7 0.25 9.9 29.6 1.1 1 0 0 1 1 1 0 DNA replication regulator SLD3 Nop53 PF07767.6 CDI84866.1 - 0.28 10.1 35.5 0.42 9.5 24.6 1.4 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Utp14 PF04615.8 CDI84866.1 - 0.57 8.2 48.9 0.69 8.0 33.9 1.0 1 0 0 1 1 1 0 Utp14 protein CDC27 PF09507.5 CDI84866.1 - 1.5 7.9 43.7 1.9 7.6 30.3 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Daxx PF03344.10 CDI84866.1 - 1.9 6.8 37.0 2.4 6.5 25.7 1.1 1 0 0 1 1 1 0 Daxx Family DUF3801 PF12687.2 CDI84866.1 - 2.3 7.7 29.3 4 6.9 20.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3801) CytochromB561_N PF09786.4 CDI84866.1 - 2.4 6.5 37.5 2.7 6.3 26.0 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal Ndc1_Nup PF09531.5 CDI84866.1 - 6.1 5.1 42.4 7.8 4.7 29.4 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup PAT1 PF09770.4 CDI84866.1 - 8.4 4.4 58.0 13 3.9 40.2 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF3337 PF11816.3 CDI84866.1 - 8.9 5.6 33.0 12 5.2 22.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3337) Med15 PF09606.5 CDI84867.1 - 0.00018 19.8 112.3 0.00023 19.5 77.8 1.0 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal DUF4407 PF14362.1 CDI84867.1 - 7.2 5.4 63.3 1.7 7.5 22.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) DALR_1 PF05746.10 CDI84868.1 - 1e-22 80.3 0.0 3.6e-08 33.3 0.0 3.4 3 1 1 4 4 4 3 DALR anticodon binding domain SprA-related PF12118.3 CDI84868.1 - 4.2e-05 23.0 12.6 5.8e-05 22.5 8.8 1.1 1 0 0 1 1 1 1 SprA-related family Suf PF05843.9 CDI84868.1 - 0.00074 19.3 3.9 0.00084 19.1 2.7 1.1 1 0 0 1 1 1 1 Suppressor of forked protein (Suf) FimP PF09766.4 CDI84868.1 - 0.0014 17.8 11.6 0.0018 17.4 8.0 1.1 1 0 0 1 1 1 1 Fms-interacting protein Spt20 PF12090.3 CDI84868.1 - 0.0018 17.6 1.3 0.0025 17.1 0.9 1.3 1 0 0 1 1 1 1 Spt20 family Peptidase_C54 PF03416.14 CDI84868.1 - 0.019 14.1 1.4 3.3 6.7 0.0 2.6 2 1 1 3 3 3 0 Peptidase family C54 BTV_NS2 PF04514.7 CDI84868.1 - 0.031 13.1 2.8 0.04 12.7 1.9 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 DUF4220 PF13968.1 CDI84868.1 - 0.073 12.1 0.9 0.093 11.8 0.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4220) CDC45 PF02724.9 CDI84868.1 - 0.1 10.5 8.8 0.14 10.1 6.1 1.1 1 0 0 1 1 1 0 CDC45-like protein Zip PF02535.17 CDI84868.1 - 0.11 11.5 1.4 0.14 11.1 1.0 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Med15 PF09606.5 CDI84868.1 - 0.12 10.5 24.1 0.19 9.9 16.7 1.3 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DDHD PF02862.12 CDI84868.1 - 0.37 10.5 9.3 0.54 10.0 6.4 1.3 1 0 0 1 1 1 0 DDHD domain Serinc PF03348.10 CDI84868.1 - 0.38 9.4 4.9 0.51 8.9 3.4 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) Raftlin PF15250.1 CDI84868.1 - 0.64 8.4 10.1 0.83 8.0 7.0 1.1 1 0 0 1 1 1 0 Raftlin Presenilin PF01080.12 CDI84868.1 - 1 8.1 5.5 1.4 7.6 3.8 1.2 1 0 0 1 1 1 0 Presenilin AIF_C PF14721.1 CDI84868.1 - 1.1 9.5 5.1 2 8.6 3.5 1.5 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Apt1 PF10351.4 CDI84868.1 - 1.4 7.7 12.9 2.2 7.0 8.9 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF2201_N PF13203.1 CDI84868.1 - 1.6 7.8 12.1 2.2 7.3 8.4 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain DUF4175 PF13779.1 CDI84868.1 - 2 5.9 24.1 2.6 5.6 16.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) CAF-1_p150 PF11600.3 CDI84868.1 - 3 7.1 27.0 0.058 12.7 12.6 1.9 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal RR_TM4-6 PF06459.7 CDI84868.1 - 3.8 7.3 8.6 5.3 6.8 6.0 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF4557 PF15101.1 CDI84868.1 - 6.8 6.4 14.8 9.8 5.9 10.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) Band_3_cyto PF07565.8 CDI84868.1 - 9.6 5.6 9.8 13 5.1 6.8 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Spore_coat_CotO PF14153.1 CDI84869.1 - 0.095 12.1 25.6 0.11 11.9 17.8 1.2 1 0 0 1 1 1 0 Spore coat protein CotO CDC45 PF02724.9 CDI84869.1 - 0.22 9.5 17.1 0.24 9.3 11.9 1.0 1 0 0 1 1 1 0 CDC45-like protein Cellulose_synt PF03552.9 CDI84869.1 - 0.22 9.7 6.9 0.26 9.5 4.8 1.0 1 0 0 1 1 1 0 Cellulose synthase DUF4175 PF13779.1 CDI84869.1 - 0.25 8.9 53.0 0.29 8.7 36.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Pox_Ag35 PF03286.9 CDI84869.1 - 0.34 10.4 15.1 0.5 9.8 10.5 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Herpes_env PF01673.13 CDI84869.1 - 0.42 9.1 11.3 0.47 8.9 7.8 1.0 1 0 0 1 1 1 0 Herpesvirus putative major envelope glycoprotein eIF-3c_N PF05470.7 CDI84869.1 - 0.5 8.3 14.1 0.59 8.1 9.8 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus DUF4045 PF13254.1 CDI84869.1 - 0.63 9.2 16.8 0.72 9.0 11.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) DDRGK PF09756.4 CDI84869.1 - 0.67 9.3 26.6 0.86 8.9 18.4 1.3 1 0 0 1 1 1 0 DDRGK domain SpaB_C PF14028.1 CDI84869.1 - 0.74 9.3 7.4 0.98 8.9 5.1 1.1 1 0 0 1 1 1 0 SpaB C-terminal domain SAPS PF04499.10 CDI84869.1 - 0.86 8.1 14.8 0.95 8.0 10.3 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein GAGA_bind PF06217.7 CDI84869.1 - 0.87 9.4 16.1 0.95 9.3 11.2 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family PAT1 PF09770.4 CDI84869.1 - 0.89 7.7 48.3 0.93 7.6 33.5 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DHHW PF14286.1 CDI84869.1 - 1.1 8.5 11.3 1.1 8.4 7.8 1.2 1 0 0 1 1 1 0 DHHW protein Plasmodium_Vir PF05795.6 CDI84869.1 - 1.3 8.1 7.1 1.5 7.9 4.9 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein eIF-3_zeta PF05091.7 CDI84869.1 - 1.3 7.5 20.5 1.4 7.4 14.2 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Ycf1 PF05758.7 CDI84869.1 - 1.7 6.2 17.8 1.8 6.1 12.3 1.0 1 0 0 1 1 1 0 Ycf1 DUF605 PF04652.11 CDI84869.1 - 1.9 7.8 23.1 2.5 7.4 16.0 1.4 1 0 0 1 1 1 0 Vta1 like SPX PF03105.14 CDI84869.1 - 2.2 7.9 18.5 2.7 7.6 12.8 1.2 1 0 0 1 1 1 0 SPX domain DUF2370 PF10176.4 CDI84869.1 - 2.3 7.5 9.3 3.5 6.8 6.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) SAGA-Tad1 PF12767.2 CDI84869.1 - 2.3 7.7 21.5 2.9 7.4 14.9 1.3 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit VID27 PF08553.5 CDI84869.1 - 2.5 6.2 12.2 2.8 6.0 8.4 1.1 1 0 0 1 1 1 0 VID27 cytoplasmic protein Med15 PF09606.5 CDI84869.1 - 2.6 6.1 66.3 2.7 6.0 46.0 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF2201_N PF13203.1 CDI84869.1 - 2.7 7.0 20.5 3 6.9 14.2 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain HSP70 PF00012.15 CDI84869.1 - 2.7 5.7 15.1 3.4 5.4 10.5 1.1 1 0 0 1 1 1 0 Hsp70 protein NARP1 PF12569.3 CDI84869.1 - 2.9 6.5 17.7 3.8 6.1 12.3 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DUF966 PF06136.8 CDI84869.1 - 3.6 6.9 19.2 4.6 6.5 13.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) TFIIA PF03153.8 CDI84869.1 - 4.4 7.1 37.0 5.1 6.8 25.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PLRV_ORF5 PF01690.12 CDI84869.1 - 4.4 6.3 21.1 5.5 6.0 14.7 1.0 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Peptidase_S15 PF02129.13 CDI84869.1 - 4.5 6.6 12.6 5.4 6.3 8.7 1.3 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Hid1 PF12722.2 CDI84869.1 - 4.9 4.6 22.2 5.5 4.5 15.4 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Rtf2 PF04641.7 CDI84869.1 - 5.2 6.1 23.4 3.4 6.7 15.3 1.3 2 0 0 2 2 1 0 Rtf2 RING-finger Presenilin PF01080.12 CDI84869.1 - 5.7 5.6 9.6 5.8 5.6 6.6 1.2 1 0 0 1 1 1 0 Presenilin Spore_YhcN_YlaJ PF09580.5 CDI84869.1 - 6.3 6.8 17.6 8.2 6.5 12.2 1.4 1 0 0 1 1 1 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) CMV_1a PF12467.3 CDI84869.1 - 7.1 6.9 15.3 10 6.4 10.6 1.3 1 0 0 1 1 1 0 Cucumber mosaic virus 1a protein family Zip PF02535.17 CDI84869.1 - 8.7 5.2 11.6 14 4.5 8.1 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter DUF1800 PF08811.6 CDI84869.1 - 8.8 5.1 21.5 9.4 5.0 14.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1800) PRTP PF01366.13 CDI84869.1 - 9 4.1 15.5 13 3.5 10.7 1.2 1 0 0 1 1 1 0 Herpesvirus processing and transport protein DUF913 PF06025.7 CDI84869.1 - 9.4 4.8 8.7 11 4.6 6.1 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Het-C PF07217.6 CDI84869.1 - 9.9 4.2 13.1 11 4.1 9.0 1.1 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C Leu_zip PF15294.1 CDI84870.1 - 0.0055 15.8 5.0 0.0067 15.5 3.4 1.1 1 0 0 1 1 1 1 Leucine zipper Dynactin_p22 PF07426.6 CDI84870.1 - 0.04 13.2 0.2 0.07 12.4 0.1 1.4 1 0 0 1 1 1 0 Dynactin subunit p22 Ribosomal_L5 PF00281.14 CDI84870.1 - 0.12 12.1 0.0 13 5.6 0.0 2.7 2 0 0 2 2 2 0 Ribosomal protein L5 SCRG1 PF15224.1 CDI84870.1 - 0.13 12.0 0.0 0.25 11.1 0.0 1.3 1 0 0 1 1 1 0 Scrapie-responsive protein 1 DUF2340 PF10209.4 CDI84870.1 - 0.14 12.3 0.1 0.27 11.4 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2340) Prefoldin_2 PF01920.15 CDI84870.1 - 0.33 10.7 5.2 3.5 7.4 1.2 2.3 2 0 0 2 2 2 0 Prefoldin subunit DUF533 PF04391.7 CDI84871.1 - 0.00086 18.7 4.6 0.00086 18.7 3.2 2.6 2 1 1 3 3 3 1 Protein of unknown function (DUF533) SR-25 PF10500.4 CDI84871.1 - 0.0098 15.3 19.5 0.0098 15.3 13.5 3.1 1 1 1 3 3 2 1 Nuclear RNA-splicing-associated protein FYDLN_acid PF09538.5 CDI84871.1 - 0.015 15.8 8.3 1.1 9.8 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) FimP PF09766.4 CDI84871.1 - 0.027 13.5 31.0 0.2 10.6 7.3 2.1 2 0 0 2 2 2 0 Fms-interacting protein DUF2052 PF09747.4 CDI84871.1 - 0.03 14.2 21.3 0.25 11.2 3.4 2.1 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) CIAPIN1 PF05093.8 CDI84871.1 - 0.055 13.5 11.1 0.41 10.7 0.9 2.6 2 0 0 2 2 2 0 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis AAA_11 PF13086.1 CDI84871.1 - 0.062 12.8 20.7 0.07 12.6 5.3 2.1 2 0 0 2 2 2 0 AAA domain ERF PF04404.7 CDI84871.1 - 0.1 12.0 23.2 0.93 9.0 6.0 2.5 2 0 0 2 2 2 0 ERF superfamily Cwf_Cwc_15 PF04889.7 CDI84871.1 - 0.16 11.6 19.3 0.84 9.2 5.4 2.1 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein DUF4175 PF13779.1 CDI84871.1 - 0.21 9.2 46.7 0.38 8.4 13.4 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4175) Striatin PF08232.7 CDI84871.1 - 0.23 11.7 23.8 1.6 9.0 6.8 2.2 2 0 0 2 2 2 0 Striatin family DUF1510 PF07423.6 CDI84871.1 - 0.26 10.6 22.9 1.1 8.6 7.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) zf-DHHC PF01529.15 CDI84871.1 - 0.36 10.2 8.2 1.6 8.1 0.4 2.2 2 0 0 2 2 2 0 DHHC palmitoyltransferase CobT PF06213.7 CDI84871.1 - 0.47 9.5 21.4 1 8.4 7.8 2.1 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT DUF4366 PF14283.1 CDI84871.1 - 0.6 9.4 13.0 6.7 6.0 8.7 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4366) Spore_coat_CotO PF14153.1 CDI84871.1 - 0.64 9.4 24.5 1.3 8.4 5.4 2.1 2 0 0 2 2 2 0 Spore coat protein CotO Mem_trans PF03547.13 CDI84871.1 - 0.9 7.7 18.3 0.18 10.0 2.9 2.2 2 0 0 2 2 2 0 Membrane transport protein Host_attach PF10116.4 CDI84871.1 - 0.94 9.7 23.1 0.088 13.0 3.0 2.4 2 0 0 2 2 2 0 Protein required for attachment to host cells Tom37_C PF11801.3 CDI84871.1 - 1 9.2 22.4 0.071 12.9 4.9 2.1 2 0 0 2 2 2 0 Tom37 C-terminal domain DUF1777 PF08648.7 CDI84871.1 - 1 9.0 22.4 0.53 9.9 4.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1777) Band_3_cyto PF07565.8 CDI84871.1 - 1.2 8.6 22.8 0.37 10.2 3.7 2.1 2 0 0 2 2 2 0 Band 3 cytoplasmic domain CDC45 PF02724.9 CDI84871.1 - 1.2 7.0 24.4 0.81 7.6 4.4 2.1 2 0 0 2 2 2 0 CDC45-like protein DUF3807 PF12720.2 CDI84871.1 - 1.2 9.2 27.1 3.6 7.7 8.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3807) DUF1390 PF07150.6 CDI84871.1 - 1.4 8.2 9.7 0.031 13.6 0.8 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1390) LIM_bind PF01803.11 CDI84871.1 - 1.9 7.5 20.4 0.074 12.1 3.3 2.1 2 0 0 2 2 2 0 LIM-domain binding protein DUF1840 PF08895.6 CDI84871.1 - 2.3 8.3 12.2 2 8.4 0.7 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1840) AIF_C PF14721.1 CDI84871.1 - 2.5 8.3 20.2 1.1 9.5 2.8 2.4 2 0 0 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term FHIPEP PF00771.15 CDI84871.1 - 2.7 6.2 16.6 1.7 6.8 3.5 2.1 2 0 0 2 2 2 0 FHIPEP family CagX PF03524.10 CDI84871.1 - 3.4 6.8 15.4 1.7 7.9 1.4 2.3 2 0 0 2 2 2 0 Conjugal transfer protein DDRGK PF09756.4 CDI84871.1 - 3.5 7.0 24.1 1.8 7.9 4.8 2.1 2 0 0 2 2 2 0 DDRGK domain Tim54 PF11711.3 CDI84871.1 - 3.9 5.9 15.5 1.9 6.9 1.0 2.1 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 FlaG PF03646.10 CDI84871.1 - 4.1 7.5 31.7 2.6 8.2 8.4 2.5 2 0 0 2 2 2 0 FlaG protein Spore_YhcN_YlaJ PF09580.5 CDI84871.1 - 4.2 7.4 23.9 1 9.4 4.9 2.1 2 0 0 2 2 2 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) Sec62 PF03839.11 CDI84871.1 - 4.7 6.5 10.5 1.1 8.6 0.7 2.1 2 0 0 2 2 2 0 Translocation protein Sec62 Baculo_PP31 PF05311.6 CDI84871.1 - 4.8 6.3 21.9 0.27 10.4 4.3 2.2 2 0 0 2 2 2 0 Baculovirus 33KDa late protein (PP31) Bud13 PF09736.4 CDI84871.1 - 5.2 7.3 24.1 2.5 8.3 5.1 2.1 2 0 0 2 2 2 0 Pre-mRNA-splicing factor of RES complex Rhabdo_ncap PF00945.13 CDI84871.1 - 5.6 5.4 10.6 1.1 7.8 0.6 2.1 2 0 0 2 2 2 0 Rhabdovirus nucleocapsid protein F-protein PF00469.15 CDI84871.1 - 6 6.1 18.9 0.53 9.6 3.2 2.1 2 0 0 2 2 2 0 Negative factor, (F-Protein) or Nef DUF3801 PF12687.2 CDI84871.1 - 6.1 6.3 19.5 1.3 8.5 0.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3801) FAM176 PF14851.1 CDI84871.1 - 6.4 6.4 19.0 4.5 6.9 4.4 2.2 2 0 0 2 2 2 0 FAM176 family Radial_spoke_3 PF06098.6 CDI84871.1 - 6.8 5.5 22.0 0.14 11.0 4.2 2.1 2 0 0 2 2 2 0 Radial spoke protein 3 Pex16 PF08610.5 CDI84871.1 - 7.3 5.4 21.6 5.6 5.8 6.9 2.1 2 0 0 2 2 2 0 Peroxisomal membrane protein (Pex16) Peptidase_S49_N PF08496.5 CDI84871.1 - 7.4 6.3 15.4 0.62 9.8 1.2 2.2 2 0 0 2 2 2 0 Peptidase family S49 N-terminal DUF3408 PF11888.3 CDI84871.1 - 7.6 6.4 21.6 1.3 8.8 4.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3408) DUF912 PF06024.7 CDI84871.1 - 7.8 6.6 14.1 1.9 8.5 1.0 2.5 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Adeno_E1A PF02703.9 CDI84871.1 - 8 5.8 12.0 0.57 9.5 1.1 2.1 2 0 0 2 2 2 0 Early E1A protein SelP_N PF04592.9 CDI84871.1 - 8.7 5.6 19.0 2.7 7.3 5.2 2.1 2 0 0 2 2 2 0 Selenoprotein P, N terminal region DUF4557 PF15101.1 CDI84871.1 - 8.8 6.1 34.0 5.9 6.6 6.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4557) PAT1 PF09770.4 CDI84871.1 - 9.1 4.3 45.0 12 3.9 31.2 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Rad51 PF08423.6 CDI84872.1 - 0.00011 21.2 0.4 0.19 10.6 0.0 3.6 3 1 1 4 4 4 2 Rad51 AAA_18 PF13238.1 CDI84872.1 - 0.0058 16.9 0.0 0.013 15.7 0.0 1.6 1 1 0 1 1 1 1 AAA domain SOBP PF15279.1 CDI84872.1 - 0.14 12.5 10.1 0.22 11.8 7.0 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein Phage_int_SAM_5 PF13102.1 CDI84872.1 - 1.4 8.9 10.5 0.43 10.5 4.4 2.1 2 0 0 2 2 2 0 Phage integrase SAM-like domain AAA_25 PF13481.1 CDI84872.1 - 1.5 8.1 8.4 1.2 8.5 0.0 2.5 1 1 1 2 2 2 0 AAA domain AAA_22 PF13401.1 CDI84872.1 - 3.5 7.7 6.6 19 5.4 4.6 2.5 1 1 0 1 1 1 0 AAA domain BTV_NS2 PF04514.7 CDI84872.1 - 5.3 5.8 11.9 8.4 5.1 8.2 1.3 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 AAA_33 PF13671.1 CDI84872.1 - 7.2 6.4 21.1 0.11 12.3 2.5 3.0 2 1 1 3 3 3 0 AAA domain NACHT PF05729.7 CDI84872.1 - 9 5.9 12.3 0.27 10.8 0.2 2.7 3 0 0 3 3 3 0 NACHT domain Ycf1 PF05758.7 CDI84877.1 - 0.0002 19.2 4.4 0.0002 19.2 3.0 7.2 4 2 0 4 4 4 1 Ycf1 KH_1 PF00013.24 CDI84877.1 - 0.16 11.6 0.0 0.35 10.5 0.0 1.5 1 0 0 1 1 1 0 KH domain KH_3 PF13014.1 CDI84877.1 - 0.17 11.5 0.0 0.31 10.7 0.0 1.4 1 0 0 1 1 1 0 KH domain ATAD4 PF15321.1 CDI84877.1 - 0.45 11.5 0.0 0.45 11.5 0.0 11.5 9 2 0 9 9 9 0 ATPase family AAA domain containing 4 AAA_23 PF13476.1 CDI84879.1 - 0.012 15.9 1.6 0.012 15.9 1.1 2.3 2 0 0 2 2 2 0 AAA domain Hamartin PF04388.7 CDI84882.1 - 1.9 7.0 21.9 2.4 6.7 15.2 1.1 1 0 0 1 1 1 0 Hamartin protein PAT1 PF09770.4 CDI84882.1 - 2.2 6.4 68.4 2.8 6.0 47.4 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TFIIA PF03153.8 CDI84882.1 - 3 7.6 59.4 3.9 7.2 41.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Utp14 PF04615.8 CDI84882.1 - 6.4 4.8 46.8 8.1 4.4 32.5 1.0 1 0 0 1 1 1 0 Utp14 protein SPT6_acidic PF14632.1 CDI84882.1 - 7.1 6.8 25.1 7.6 6.7 1.3 2.4 2 0 0 2 2 2 0 Acidic N-terminal SPT6 Arm PF00514.18 CDI84883.1 - 0.0019 17.9 49.6 0.0083 15.9 0.7 8.2 9 0 0 9 9 9 6 Armadillo/beta-catenin-like repeat AAA_23 PF13476.1 CDI84883.1 - 1.5 9.0 6.6 12 6.1 1.7 2.5 2 1 0 2 2 2 0 AAA domain NOC3p PF07540.6 CDI84884.1 - 3.8e-06 27.0 0.0 3.8e-06 27.0 0.0 3.2 2 1 1 3 3 3 1 Nucleolar complex-associated protein Zip PF02535.17 CDI84884.1 - 5.3 5.9 8.8 2.7 6.8 0.5 2.4 2 0 0 2 2 2 0 ZIP Zinc transporter DSPc PF00782.15 CDI84885.1 - 2.2e-08 33.7 0.1 9.2e-08 31.7 0.0 2.0 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 CDI84885.1 - 1.7e-05 24.2 0.1 9.8e-05 21.7 0.0 1.9 2 0 0 2 2 2 1 Protein-tyrosine phosphatase Glyco_trans_4_4 PF13579.1 CDI84885.1 - 0.019 15.0 1.7 0.019 15.0 1.1 2.6 3 0 0 3 3 3 0 Glycosyl transferase 4-like domain Spt20 PF12090.3 CDI84885.1 - 0.027 13.8 4.8 0.48 9.7 3.5 2.1 2 0 0 2 2 2 0 Spt20 family U1snRNP70_N PF12220.3 CDI84885.1 - 0.21 11.9 9.8 0.47 10.8 6.8 1.5 1 0 0 1 1 1 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal Nucleoporin2 PF04096.9 CDI84885.1 - 0.45 10.3 5.0 5.1 6.9 2.2 2.2 2 0 0 2 2 2 0 Nucleoporin autopeptidase PAT1 PF09770.4 CDI84885.1 - 0.57 8.3 17.2 0.39 8.9 8.8 2.0 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 Suf PF05843.9 CDI84885.1 - 0.73 9.5 11.1 0.024 14.3 3.5 1.5 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) Pex14_N PF04695.8 CDI84885.1 - 2.2 8.3 13.4 1.3 9.0 5.9 2.6 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Maf PF02545.9 CDI84886.1 - 4.9e-21 74.7 0.0 4.4e-07 29.2 0.0 3.1 3 0 0 3 3 3 3 Maf-like protein DUF2361 PF10153.4 CDI84887.1 - 0.34 11.1 18.5 0.059 13.5 8.0 2.8 2 1 0 2 2 2 0 Uncharacterised conserved protein (DUF2361) Coatomer_WDAD PF04053.9 CDI84888.1 - 6.4e-78 262.5 0.0 1.7e-77 261.1 0.0 1.6 1 1 0 1 1 1 1 Coatomer WD associated region COPI_C PF06957.6 CDI84888.1 - 1.3e-41 142.4 0.1 8.3e-25 87.1 0.0 2.2 1 1 1 2 2 2 2 Coatomer (COPI) alpha subunit C-terminus WD40 PF00400.27 CDI84888.1 - 6.3e-41 136.8 5.7 3.3e-08 33.0 0.0 6.9 6 0 0 6 6 6 6 WD domain, G-beta repeat Apc4_WD40 PF12894.2 CDI84888.1 - 0.017 14.6 0.0 3 7.4 0.0 3.1 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain TPR_2 PF07719.12 CDI84888.1 - 0.034 14.0 5.7 3.4 7.8 0.1 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat Nucleoporin_N PF08801.6 CDI84888.1 - 0.041 12.6 0.0 0.52 9.0 0.0 2.1 2 0 0 2 2 2 0 Nup133 N terminal like Nup160 PF11715.3 CDI84888.1 - 0.075 11.1 0.8 0.24 9.4 0.5 1.7 1 1 0 1 1 1 0 Nucleoporin Nup120/160 TPR_14 PF13428.1 CDI84888.1 - 0.12 13.1 10.2 28 5.7 0.0 5.5 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.1 CDI84888.1 - 0.34 11.6 8.9 8.2 7.2 0.4 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.1 CDI84888.1 - 0.4 11.0 7.3 1 9.7 1.3 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat AAA_2 PF07724.9 CDI84889.1 - 6.2e-48 162.9 0.1 1e-45 155.6 0.0 2.8 3 0 0 3 3 2 1 AAA domain (Cdc48 subfamily) AAA PF00004.24 CDI84889.1 - 5.2e-23 81.7 0.0 6.8e-13 48.9 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.4 CDI84889.1 - 1.9e-20 72.5 0.4 9.6e-20 70.2 0.3 2.4 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein Clp_N PF02861.15 CDI84889.1 - 1e-14 54.2 4.8 1.6e-08 34.3 0.1 3.5 4 0 0 4 4 2 2 Clp amino terminal domain AAA_5 PF07728.9 CDI84889.1 - 9e-14 51.3 0.1 1.6e-07 31.1 0.0 3.3 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 CDI84889.1 - 1.9e-08 34.5 14.2 5.9e-05 23.1 0.0 5.9 3 2 1 4 4 4 2 AAA ATPase domain AAA_22 PF13401.1 CDI84889.1 - 4.9e-08 33.1 0.3 0.0054 16.8 0.0 4.1 2 1 1 3 3 3 2 AAA domain Sigma54_activat PF00158.21 CDI84889.1 - 2e-07 30.6 0.0 0.00074 19.0 0.0 3.3 3 1 0 3 3 3 2 Sigma-54 interaction domain AAA_14 PF13173.1 CDI84889.1 - 9.1e-07 28.8 0.0 0.011 15.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain Arch_ATPase PF01637.13 CDI84889.1 - 1.7e-05 24.6 0.3 0.39 10.3 0.1 3.8 2 1 0 3 3 3 1 Archaeal ATPase AAA_17 PF13207.1 CDI84889.1 - 7.8e-05 23.4 5.0 0.38 11.5 0.1 3.8 2 2 0 3 3 3 2 AAA domain AAA_18 PF13238.1 CDI84889.1 - 0.00012 22.3 0.3 1.1 9.5 0.0 3.4 3 0 0 3 3 3 2 AAA domain AAA_3 PF07726.6 CDI84889.1 - 0.0064 16.0 0.0 0.49 10.0 0.0 3.2 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.17 CDI84889.1 - 0.0078 16.3 0.0 2.5 8.3 0.0 2.9 2 0 0 2 2 2 1 RNA helicase AAA_25 PF13481.1 CDI84889.1 - 0.0087 15.4 0.1 0.84 9.0 0.0 3.4 2 1 1 3 3 3 1 AAA domain IstB_IS21 PF01695.12 CDI84889.1 - 0.0088 15.4 0.0 0.062 12.7 0.0 2.4 2 0 0 2 2 2 1 IstB-like ATP binding protein Torsin PF06309.6 CDI84889.1 - 0.011 15.6 0.0 0.17 11.7 0.0 2.6 3 0 0 3 3 2 0 Torsin DUF815 PF05673.8 CDI84889.1 - 0.02 13.8 0.0 0.36 9.7 0.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF815) AAA_19 PF13245.1 CDI84889.1 - 0.02 14.6 0.1 0.5 10.1 0.0 3.0 2 0 0 2 2 2 0 Part of AAA domain DUF87 PF01935.12 CDI84889.1 - 0.021 14.6 3.1 0.66 9.7 0.0 3.5 3 1 0 3 3 3 0 Domain of unknown function DUF87 MMR_HSR1 PF01926.18 CDI84889.1 - 0.024 14.6 0.0 0.16 11.9 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase DUF258 PF03193.11 CDI84889.1 - 0.025 13.7 0.0 0.98 8.5 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function, DUF258 ABC_tran PF00005.22 CDI84889.1 - 0.026 14.8 0.1 15 5.8 0.0 3.0 3 0 0 3 3 3 0 ABC transporter DNA_pol3_delta2 PF13177.1 CDI84889.1 - 0.12 12.0 0.0 1.2 8.8 0.0 2.4 1 1 0 1 1 1 0 DNA polymerase III, delta subunit Phage_GP20 PF06810.6 CDI84889.1 - 0.64 9.4 11.9 2.8 7.3 3.6 2.8 3 0 0 3 3 3 0 Phage minor structural protein GP20 AAA_12 PF13087.1 CDI84890.1 - 1.9e-24 86.1 0.0 1.1e-15 57.5 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_11 PF13086.1 CDI84890.1 - 5.4e-13 49.0 0.1 2e-08 34.1 0.0 2.4 1 1 1 2 2 2 2 AAA domain AAA_30 PF13604.1 CDI84890.1 - 2.7e-08 33.6 0.2 1.1e-07 31.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 CDI84890.1 - 4e-06 26.4 4.5 6.6e-06 25.7 0.1 3.5 3 0 0 3 3 3 1 Part of AAA domain AAA PF00004.24 CDI84890.1 - 0.21 11.8 0.0 0.46 10.6 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Asn_synthase PF00733.16 CDI84893.1 - 4.6e-23 82.0 0.3 3.4e-16 59.5 0.0 2.8 2 1 0 2 2 2 2 Asparagine synthase Lectin_leg-like PF03388.8 CDI84894.1 - 3.3e-09 36.2 0.1 9.2e-09 34.7 0.1 1.7 1 1 0 1 1 1 1 Legume-like lectin family Got1 PF04178.7 CDI84895.1 - 9.7e-25 86.9 15.0 1.5e-24 86.3 10.4 1.3 1 0 0 1 1 1 1 Got1/Sft2-like family DUF2076 PF09849.4 CDI84895.1 - 0.34 10.9 2.1 0.55 10.2 1.4 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Myb_Cef PF11831.3 CDI84896.1 - 2.4e-27 95.6 1.9 2.4e-27 95.6 1.3 3.8 3 1 0 3 3 3 1 pre-mRNA splicing factor component Myb_DNA-bind_6 PF13921.1 CDI84896.1 - 3.4e-13 49.4 7.3 2.6e-12 46.6 3.0 3.8 3 1 1 4 4 4 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 CDI84896.1 - 9.8e-13 47.9 5.5 4.5e-11 42.6 0.2 4.2 5 0 0 5 5 5 2 Myb-like DNA-binding domain Rap1_C PF11626.3 CDI84896.1 - 0.11 12.3 8.4 4 7.4 0.1 3.7 3 0 0 3 3 3 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Chorein_N PF12624.2 CDI84897.1 - 2e-05 24.0 0.0 4e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 N-terminal region of Chorein, a TM vesicle-mediated sorter Choline_transpo PF04515.7 CDI84897.1 - 5.9 5.5 0.0 9.4 4.8 0.0 1.2 1 0 0 1 1 1 0 Plasma-membrane choline transporter SR-25 PF10500.4 CDI84898.1 - 0.00078 18.9 8.8 0.00078 18.9 6.1 6.0 7 0 0 7 7 7 3 Nuclear RNA-splicing-associated protein TFIIA PF03153.8 CDI84898.1 - 0.002 18.1 14.8 0.002 18.1 10.3 2.1 2 1 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit TPM PF04536.9 CDI84899.1 - 9.7e-05 22.2 0.0 0.00018 21.3 0.0 1.4 1 0 0 1 1 1 1 TLP18.3, Psb32 and MOLO-1 founding proteins of phosphatase MMR_HSR1 PF01926.18 CDI84900.1 - 3e-18 65.8 0.0 4.9e-18 65.1 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 CDI84900.1 - 1.2e-07 31.1 0.0 1.3e-06 27.8 0.0 2.3 2 0 0 2 2 2 1 Ferrous iron transport protein B Miro PF08477.8 CDI84900.1 - 1.7e-06 28.4 0.0 3.5e-05 24.2 0.0 2.2 2 0 0 2 2 2 1 Miro-like protein Dynamin_N PF00350.18 CDI84900.1 - 2.3e-06 27.5 0.4 0.00029 20.6 0.1 2.2 2 0 0 2 2 2 1 Dynamin family GTP_EFTU PF00009.22 CDI84900.1 - 3.4e-06 26.6 0.0 0.036 13.4 0.0 3.1 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain AIG1 PF04548.11 CDI84900.1 - 0.00018 20.6 0.1 0.00026 20.1 0.0 1.2 1 0 0 1 1 1 1 AIG1 family DUF258 PF03193.11 CDI84900.1 - 0.012 14.7 0.0 0.021 14.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_29 PF13555.1 CDI84900.1 - 0.015 14.8 0.0 0.031 13.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.22 CDI84900.1 - 0.037 14.3 0.0 0.061 13.6 0.0 1.4 1 0 0 1 1 1 0 ABC transporter AAA_21 PF13304.1 CDI84900.1 - 0.058 13.3 0.2 0.084 12.8 0.1 1.2 1 0 0 1 1 1 0 AAA domain KH_2 PF07650.12 CDI84900.1 - 0.097 12.2 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 KH domain cobW PF02492.14 CDI84900.1 - 0.13 11.7 0.1 4.2 6.7 0.0 2.6 2 2 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain PTH2 PF01981.11 CDI84901.1 - 1.7e-08 34.1 0.1 1.9e-08 34.0 0.1 1.2 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 WD40 PF00400.27 CDI84902.1 - 9.9e-15 53.7 16.8 2.9e-07 30.1 0.2 5.2 5 0 0 5 5 5 4 WD domain, G-beta repeat DUF385 PF04075.9 CDI84902.1 - 0.0039 17.1 0.1 0.0087 16.0 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF385) Telomere_Sde2_2 PF13297.1 CDI84903.1 - 1.2e-18 66.0 0.2 2.7e-18 64.9 0.1 1.6 1 0 0 1 1 1 1 Telomere stability C-terminal Telomere_Sde2 PF13019.1 CDI84903.1 - 2.1e-12 47.0 0.1 2.1e-12 47.0 0.0 3.2 4 0 0 4 4 4 1 Telomere stability and silencing DUF4168 PF13767.1 CDI84903.1 - 9.3 6.9 12.7 0.37 11.4 4.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4168) SLBP_RNA_bind PF15247.1 CDI84904.1 - 1.4e-20 72.7 1.1 1.4e-20 72.7 0.8 1.7 2 0 0 2 2 2 1 Histone RNA hairpin-binding protein RNA-binding domain TerB PF05099.8 CDI84904.1 - 0.024 14.3 0.3 0.051 13.3 0.2 1.5 1 0 0 1 1 1 0 Tellurite resistance protein TerB Ribosomal_S8 PF00410.14 CDI84905.1 - 3.3e-25 88.4 0.0 4.1e-25 88.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S8 Mito_carr PF00153.22 CDI84906.1 - 7.1e-46 153.8 5.1 6.3e-17 61.0 0.1 3.4 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_6 PF13405.1 CDI84907.1 - 4.2e-11 41.7 5.5 3.6e-07 29.5 0.1 4.8 5 1 1 6 6 6 2 EF-hand domain EF-hand_7 PF13499.1 CDI84907.1 - 5.2e-11 42.5 2.0 2.3e-05 24.4 0.0 3.4 3 1 0 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.27 CDI84907.1 - 1.4e-09 36.5 5.7 4.7e-06 25.5 0.1 5.2 6 0 0 6 6 6 2 EF hand EF-hand_8 PF13833.1 CDI84907.1 - 3e-09 36.3 3.0 2.7e-05 23.6 0.2 4.0 3 2 1 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.1 CDI84907.1 - 0.00061 19.0 3.3 0.04 13.2 0.0 3.6 3 0 0 3 3 3 1 EF hand EF-hand_9 PF14658.1 CDI84907.1 - 0.016 15.0 0.0 0.081 12.8 0.0 2.1 3 0 0 3 3 3 0 EF-hand domain EFhand_Ca_insen PF08726.5 CDI84907.1 - 0.025 14.5 0.0 13 5.8 0.0 2.9 2 1 0 2 2 2 0 Ca2+ insensitive EF hand cNMP_binding PF00027.24 CDI84908.1 - 9.4e-18 63.8 0.0 2.2e-17 62.6 0.0 1.7 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain DUF1564 PF07600.6 CDI84908.1 - 0.14 11.4 0.5 0.32 10.2 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1564) DEAD PF00270.24 CDI84909.1 - 6.8e-40 136.3 0.0 1.5e-39 135.1 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CDI84909.1 - 5.5e-24 83.8 0.0 1.2e-23 82.6 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Cyt-b5 PF00173.23 CDI84910.1 - 1.5e-23 82.3 0.1 2.1e-23 81.9 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DnaJ PF00226.26 CDI84911.1 - 1.3e-15 56.8 0.0 3.7e-15 55.4 0.0 1.8 1 0 0 1 1 1 1 DnaJ domain TPR_11 PF13414.1 CDI84912.1 - 1.1e-05 24.9 9.8 2.9e-05 23.6 0.7 3.6 2 1 1 3 3 3 1 TPR repeat TPR_1 PF00515.23 CDI84912.1 - 2.4e-05 23.7 4.1 0.00016 21.1 1.4 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.12 CDI84912.1 - 7.9e-05 22.2 4.6 0.0015 18.3 0.5 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat SPX PF03105.14 CDI84912.1 - 0.00059 19.7 20.6 0.00068 19.5 14.3 1.3 1 0 0 1 1 1 1 SPX domain PAT1 PF09770.4 CDI84912.1 - 0.00084 17.7 66.9 0.00095 17.5 46.4 1.1 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 Nha1_C PF08619.5 CDI84912.1 - 0.0013 18.1 19.2 0.0013 18.1 13.3 1.5 2 0 0 2 2 2 1 Alkali metal cation/H+ antiporter Nha1 C terminus Ycf1 PF05758.7 CDI84912.1 - 0.014 13.2 28.7 0.018 12.8 19.9 1.1 1 0 0 1 1 1 0 Ycf1 Hid1 PF12722.2 CDI84912.1 - 0.03 12.0 26.6 0.039 11.6 18.4 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Pox_Ag35 PF03286.9 CDI84912.1 - 0.08 12.4 17.1 0.19 11.2 11.9 1.6 1 0 0 1 1 1 0 Pox virus Ag35 surface protein GPCR_chapero_1 PF11904.3 CDI84912.1 - 0.51 9.4 24.4 0.74 8.8 16.9 1.2 1 0 0 1 1 1 0 GPCR-chaperone GAGA_bind PF06217.7 CDI84912.1 - 0.65 9.9 31.7 0.065 13.1 19.1 1.5 2 0 0 2 2 2 0 GAGA binding protein-like family Ndc1_Nup PF09531.5 CDI84912.1 - 0.68 8.2 22.6 0.93 7.8 15.7 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup SAPS PF04499.10 CDI84912.1 - 0.79 8.2 25.5 1.2 7.7 17.7 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Caldesmon PF02029.10 CDI84912.1 - 0.99 7.7 29.2 1.7 6.9 20.2 1.3 1 0 0 1 1 1 0 Caldesmon DUF2146 PF10220.4 CDI84912.1 - 1.1 7.1 25.2 1.5 6.7 17.5 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2146) DDRGK PF09756.4 CDI84912.1 - 1.6 8.1 49.4 0.025 13.9 29.0 1.8 2 0 0 2 2 2 0 DDRGK domain Mem_trans PF03547.13 CDI84912.1 - 1.7 6.8 11.8 2.4 6.3 8.2 1.3 1 0 0 1 1 1 0 Membrane transport protein Birna_RdRp PF04197.7 CDI84912.1 - 1.8 6.4 16.4 2.3 6.1 11.3 1.1 1 0 0 1 1 1 0 Birnavirus RNA dependent RNA polymerase (VP1) SID-1_RNA_chan PF13965.1 CDI84912.1 - 3.7 5.6 17.0 5.3 5.0 11.8 1.3 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Neur_chan_memb PF02932.11 CDI84912.1 - 4.1 7.2 23.6 2.1 8.1 15.0 1.5 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region LMBR1 PF04791.11 CDI84912.1 - 4.5 5.7 14.4 5.8 5.3 10.0 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Dicty_REP PF05086.7 CDI84912.1 - 9 3.9 20.8 12 3.5 14.4 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF4638 PF15472.1 CDI84912.1 - 9.8 5.6 25.8 18 4.8 17.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) Hairy_orange PF07527.8 CDI84913.1 - 0.029 14.1 0.5 0.062 13.0 0.3 1.6 1 0 0 1 1 1 0 Hairy Orange DUF1183 PF06682.7 CDI84917.1 - 0.013 15.0 7.0 0.013 15.0 4.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1183) SPX PF03105.14 CDI84917.1 - 0.038 13.7 17.3 0.064 13.0 12.0 1.4 1 0 0 1 1 1 0 SPX domain CTP_transf_3 PF02348.14 CDI84917.1 - 0.21 11.1 3.6 0.31 10.6 2.5 1.2 1 0 0 1 1 1 0 Cytidylyltransferase Ribosomal_60s PF00428.14 CDI84917.1 - 0.22 11.9 8.0 0.47 10.8 5.6 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein Shadoo PF14999.1 CDI84917.1 - 0.62 9.9 20.5 0.053 13.3 2.7 2.2 2 0 0 2 2 2 0 Shadow of prion protein, neuroprotective TLP-20 PF06088.6 CDI84917.1 - 1 9.0 13.9 4 7.0 0.5 2.3 2 0 0 2 2 2 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) DUF4604 PF15377.1 CDI84917.1 - 2.9 8.0 15.8 0.17 12.0 4.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4604) DUF3275 PF11679.3 CDI84917.1 - 4.5 6.8 5.5 6.6 6.2 3.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3275) Utp14 PF04615.8 CDI84917.1 - 4.7 5.2 14.1 6.1 4.8 9.8 1.1 1 0 0 1 1 1 0 Utp14 protein Striatin PF08232.7 CDI84917.1 - 9.6 6.5 13.1 4.2 7.6 3.8 2.2 2 0 0 2 2 2 0 Striatin family PGA2 PF07543.7 CDI84920.1 - 0.015 15.1 0.4 0.015 15.1 0.3 3.0 3 0 0 3 3 3 0 Protein trafficking PGA2 SR-25 PF10500.4 CDI84920.1 - 0.035 13.5 0.5 0.035 13.5 0.3 3.8 4 0 0 4 4 4 0 Nuclear RNA-splicing-associated protein SPX PF03105.14 CDI84920.1 - 0.13 11.9 8.5 1.1 8.9 0.2 2.2 2 0 0 2 2 2 0 SPX domain CDC73 PF05179.9 CDI84920.1 - 1.5 8.0 9.8 1.7 7.9 3.1 2.5 2 0 0 2 2 2 0 RNA pol II accessory factor, Cdc73 family Band_3_cyto PF07565.8 CDI84920.1 - 1.9 7.9 18.7 3.1 7.2 3.0 2.6 2 1 0 2 2 2 0 Band 3 cytoplasmic domain PBP1_TM PF14812.1 CDI84920.1 - 4.4 7.6 10.3 2.1 8.6 0.2 2.5 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal AAA_23 PF13476.1 CDI84921.1 - 0.005 17.1 7.6 0.11 12.7 2.4 2.6 2 0 0 2 2 2 2 AAA domain Suf PF05843.9 CDI84921.1 - 0.0063 16.2 3.2 0.0063 16.2 2.2 3.9 2 1 0 2 2 2 1 Suppressor of forked protein (Suf) DUF1764 PF08576.5 CDI84924.1 - 0.62 10.8 19.1 0.72 10.6 13.3 1.1 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) Pneumo_phosprot PF02478.11 CDI84924.1 - 5.4 6.4 8.2 5.5 6.4 5.7 1.0 1 0 0 1 1 1 0 Pneumovirus phosphoprotein Asp-B-Hydro_N PF05279.6 CDI84925.1 - 1.4 8.7 25.7 1.5 8.6 17.8 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Nop14 PF04147.7 CDI84926.1 - 1.1e-13 50.1 13.6 1.3e-12 46.5 7.2 2.7 2 1 0 2 2 2 2 Nop14-like family BAF1_ABF1 PF04684.8 CDI84926.1 - 0.0023 16.8 10.3 0.0023 16.8 7.1 2.3 1 1 1 2 2 2 1 BAF1 / ABF1 chromatin reorganising factor SMAP PF15477.1 CDI84926.1 - 0.045 14.0 0.7 0.045 14.0 0.5 4.0 4 1 0 4 4 4 0 Small acidic protein family BTV_NS2 PF04514.7 CDI84926.1 - 1.9 7.3 11.2 0.062 12.1 3.6 1.5 2 0 0 2 2 2 0 Bluetongue virus non-structural protein NS2 Activator_LAG-3 PF11498.3 CDI84926.1 - 10 4.7 21.0 0.23 10.1 8.8 2.1 2 0 0 2 2 2 0 Transcriptional activator LAG-3 START PF01852.14 CDI84927.1 - 0.001 18.4 0.0 0.0013 18.0 0.0 1.2 1 0 0 1 1 1 1 START domain Sporozoite_P67 PF05642.6 CDI84928.1 - 0.0037 15.1 8.2 0.0051 14.7 5.7 1.1 1 0 0 1 1 1 1 Sporozoite P67 surface antigen Ribosomal_60s PF00428.14 CDI84928.1 - 0.017 15.5 17.8 0.017 15.5 12.4 4.7 1 1 3 4 4 1 0 60s Acidic ribosomal protein CENP-B_dimeris PF09026.5 CDI84928.1 - 0.028 14.6 2.1 0.12 12.6 1.9 1.7 2 0 0 2 2 2 0 Centromere protein B dimerisation domain PBP1_TM PF14812.1 CDI84928.1 - 0.043 14.1 2.2 0.084 13.1 1.5 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Nucleoplasmin PF03066.10 CDI84928.1 - 0.11 12.0 5.0 0.17 11.4 3.5 1.3 1 0 0 1 1 1 0 Nucleoplasmin eIF3_subunit PF08597.5 CDI84928.1 - 0.41 10.1 10.5 0.59 9.6 7.3 1.3 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit TrbL PF04610.9 CDI84928.1 - 0.61 9.7 13.4 0.95 9.1 9.3 1.2 1 0 0 1 1 1 0 TrbL/VirB6 plasmid conjugal transfer protein TFIIF_alpha PF05793.7 CDI84928.1 - 0.81 7.9 6.7 0.98 7.7 4.7 1.0 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Nop14 PF04147.7 CDI84928.1 - 1 7.2 5.7 1.1 7.1 3.9 1.1 1 0 0 1 1 1 0 Nop14-like family DUF4611 PF15387.1 CDI84928.1 - 2.2 8.4 9.0 1.7 8.8 3.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) RAP1 PF07218.6 CDI84928.1 - 8 4.4 9.5 9.4 4.1 6.6 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) CAF-1_p150 PF11600.3 CDI84930.1 - 0.0032 16.8 15.8 0.0032 16.8 10.9 4.5 3 1 0 3 3 3 2 Chromatin assembly factor 1 complex p150 subunit, N-terminal RAP1 PF07218.6 CDI84930.1 - 3.1 5.8 7.6 4.9 5.1 5.3 1.4 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DUF4175 PF13779.1 CDI84931.1 - 0.0062 14.3 65.5 0.0062 14.3 19.2 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF4175) BAF1_ABF1 PF04684.8 CDI84931.1 - 0.0091 14.8 29.9 0.0091 14.8 20.7 3.6 2 1 0 3 3 3 1 BAF1 / ABF1 chromatin reorganising factor DUF1266 PF06889.6 CDI84931.1 - 0.66 9.7 19.1 0.061 13.1 2.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1266) FHIPEP PF00771.15 CDI84932.1 - 0.018 13.4 8.2 0.17 10.2 1.6 2.2 2 0 0 2 2 2 0 FHIPEP family LDB19 PF13002.2 CDI84932.1 - 0.04 13.4 1.0 0.066 12.7 0.7 1.3 1 0 0 1 1 1 0 Arrestin_N terminal like HemX PF04375.9 CDI84932.1 - 3.5 6.1 38.9 1.5 7.3 10.3 2.1 2 0 0 2 2 2 0 HemX Peptidase_S15 PF02129.13 CDI84932.1 - 5.1 6.4 22.8 4.8 6.5 4.6 2.3 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) DUF819 PF05684.7 CDI84932.1 - 7 5.3 6.1 0.38 9.5 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF819) Suf PF05843.9 CDI84933.1 - 0.0019 17.9 16.4 0.0022 17.8 11.4 1.2 1 0 0 1 1 1 1 Suppressor of forked protein (Suf) DUF3801 PF12687.2 CDI84933.1 - 0.0068 16.0 8.6 0.0084 15.7 6.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3801) FLO_LFY PF01698.11 CDI84933.1 - 0.012 14.4 9.6 0.013 14.3 6.7 1.2 1 0 0 1 1 1 0 Floricaula / Leafy protein Utp14 PF04615.8 CDI84933.1 - 0.012 13.8 13.5 0.012 13.8 9.3 1.1 1 0 0 1 1 1 0 Utp14 protein Apt1 PF10351.4 CDI84933.1 - 0.014 14.2 19.1 0.015 14.2 13.3 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain FimP PF09766.4 CDI84933.1 - 0.022 13.8 19.7 0.028 13.5 13.7 1.2 1 0 0 1 1 1 0 Fms-interacting protein SAGA-Tad1 PF12767.2 CDI84933.1 - 0.025 14.2 17.2 0.029 14.0 11.9 1.3 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit PAT1 PF09770.4 CDI84933.1 - 0.036 12.3 28.1 0.038 12.2 19.5 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 AAT PF03417.11 CDI84933.1 - 0.046 13.1 7.4 0.054 12.9 5.1 1.3 1 0 0 1 1 1 0 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase DUF605 PF04652.11 CDI84933.1 - 0.073 12.4 35.7 0.079 12.3 24.8 1.1 1 0 0 1 1 1 0 Vta1 like zf-DHHC PF01529.15 CDI84933.1 - 0.091 12.1 1.7 0.12 11.7 1.1 1.3 1 0 0 1 1 1 0 DHHC palmitoyltransferase CDC45 PF02724.9 CDI84933.1 - 0.1 10.6 19.0 0.14 10.1 13.2 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF3337 PF11816.3 CDI84933.1 - 0.12 11.7 16.9 0.17 11.2 11.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3337) Peptidase_S49_N PF08496.5 CDI84933.1 - 0.14 11.9 6.6 0.21 11.3 4.6 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Hid1 PF12722.2 CDI84933.1 - 0.15 9.6 19.2 0.16 9.6 13.3 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein NPR3 PF03666.8 CDI84933.1 - 0.23 9.9 16.6 0.34 9.3 11.5 1.3 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Band_3_cyto PF07565.8 CDI84933.1 - 0.24 10.8 13.8 0.41 10.1 9.6 1.5 1 0 0 1 1 1 0 Band 3 cytoplasmic domain BTV_NS2 PF04514.7 CDI84933.1 - 0.26 10.1 6.4 0.31 9.8 4.4 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 DUF1510 PF07423.6 CDI84933.1 - 0.27 10.5 17.2 0.46 9.8 11.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) PPP4R2 PF09184.6 CDI84933.1 - 0.35 10.3 15.0 0.42 10.0 10.4 1.2 1 0 0 1 1 1 0 PPP4R2 Raftlin PF15250.1 CDI84933.1 - 0.5 8.8 18.0 0.7 8.3 12.5 1.2 1 0 0 1 1 1 0 Raftlin Tim54 PF11711.3 CDI84933.1 - 0.52 8.8 8.8 0.77 8.2 6.1 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Spore_coat_CotO PF14153.1 CDI84933.1 - 0.6 9.5 20.2 0.89 8.9 14.0 1.2 1 0 0 1 1 1 0 Spore coat protein CotO eIF-3_zeta PF05091.7 CDI84933.1 - 0.75 8.3 14.9 0.85 8.1 10.3 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF4557 PF15101.1 CDI84933.1 - 1.1 9.0 20.8 2 8.1 14.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) DUF4613 PF15390.1 CDI84933.1 - 1.1 7.3 13.2 1.3 7.0 9.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) DUF4175 PF13779.1 CDI84933.1 - 1.2 6.7 38.2 1.6 6.3 26.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) DUF2146 PF10220.4 CDI84933.1 - 1.3 6.9 16.4 1.5 6.7 11.3 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2146) Paramyxo_ncap PF00973.14 CDI84933.1 - 1.5 7.3 16.3 1.9 7.1 11.3 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Ndc1_Nup PF09531.5 CDI84933.1 - 1.7 6.9 21.1 2.3 6.5 14.6 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup LMBR1 PF04791.11 CDI84933.1 - 1.7 7.1 7.0 2.1 6.8 4.8 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein HCO3_cotransp PF00955.16 CDI84933.1 - 1.9 7.0 5.5 2.8 6.4 3.8 1.2 1 0 0 1 1 1 0 HCO3- transporter family DUF2126 PF09899.4 CDI84933.1 - 2.2 6.2 9.1 2.8 5.8 6.3 1.1 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) Cellulose_synt PF03552.9 CDI84933.1 - 2.8 6.1 6.1 3.2 5.9 4.2 1.1 1 0 0 1 1 1 0 Cellulose synthase DUF4106 PF13388.1 CDI84933.1 - 3.3 6.5 20.9 4.1 6.2 14.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) Glyco_transf_15 PF01793.11 CDI84933.1 - 4.4 6.1 13.0 6.1 5.6 9.0 1.2 1 0 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase TFIIA PF03153.8 CDI84933.1 - 4.6 7.0 39.2 6.3 6.5 27.2 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Presenilin PF01080.12 CDI84933.1 - 4.7 5.9 21.8 6.2 5.5 15.1 1.2 1 0 0 1 1 1 0 Presenilin DUF506 PF04720.7 CDI84933.1 - 5.3 6.6 14.3 1.4 8.4 8.0 1.4 2 0 0 2 2 1 0 Protein of unknown function (DUF506) Parvo_coat PF00740.13 CDI84933.1 - 6.6 5.5 21.9 7.9 5.2 15.2 1.0 1 0 0 1 1 1 0 Parvovirus coat protein VP2 SDH_alpha PF03313.10 CDI84934.1 - 0.13 11.2 4.7 0.14 11.1 3.3 1.0 1 0 0 1 1 1 0 Serine dehydratase alpha chain CDC45 PF02724.9 CDI84934.1 - 0.26 9.2 13.2 0.32 8.9 9.2 1.0 1 0 0 1 1 1 0 CDC45-like protein Thioredoxin_9 PF14595.1 CDI84934.1 - 0.78 9.3 11.9 1.1 8.8 8.3 1.3 1 1 0 1 1 1 0 Thioredoxin COX6A PF02046.10 CDI84934.1 - 2 8.3 11.7 3 7.7 8.1 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase subunit VIa XAP5 PF04921.9 CDI84934.1 - 2.9 7.3 18.0 3.4 7.1 12.5 1.1 1 0 0 1 1 1 0 XAP5, circadian clock regulator Plasmodium_Vir PF05795.6 CDI84934.1 - 4.4 6.4 7.7 4.8 6.2 5.3 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Ycf1 PF05758.7 CDI84934.1 - 8.9 3.8 19.9 9.8 3.7 13.8 1.1 1 0 0 1 1 1 0 Ycf1 Gly-zipper_OmpA PF13436.1 CDI84935.1 - 4.3 7.0 20.0 6.8 6.3 13.9 1.3 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain FliD_N PF02465.13 CDI84935.1 - 4.7 7.6 15.1 6.7 7.1 10.5 1.3 1 1 0 1 1 1 0 Flagellar hook-associated protein 2 N-terminus Med15 PF09606.5 CDI84935.1 - 6.4 4.8 17.9 8.9 4.3 12.4 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF3439 PF11921.3 CDI84936.1 - 0.0016 18.1 0.1 0.0016 18.1 0.1 2.7 2 2 1 4 4 4 1 Domain of unknown function (DUF3439) Ribosomal_60s PF00428.14 CDI84936.1 - 0.03 14.7 23.5 0.49 10.8 5.6 2.5 2 0 0 2 2 2 0 60s Acidic ribosomal protein Myco_19_kDa PF05481.7 CDI84936.1 - 0.047 13.5 0.4 0.047 13.5 0.3 2.4 2 0 0 2 2 2 0 Mycobacterium 19 kDa lipoprotein antigen DUF3123 PF11321.3 CDI84936.1 - 0.33 11.2 16.5 1.7 8.9 4.5 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3123) Spore_coat_CotO PF14153.1 CDI84938.1 - 0.0044 16.4 1.0 0.0044 16.4 0.7 3.9 2 1 2 4 4 4 1 Spore coat protein CotO BRF1 PF07741.8 CDI84938.1 - 0.12 12.5 0.0 0.12 12.5 0.0 4.3 3 1 0 3 3 3 0 Brf1-like TBP-binding domain ig PF00047.20 CDI84938.1 - 1.3 9.1 0.0 1.3 9.1 0.0 3.7 3 1 1 4 4 4 0 Immunoglobulin domain PAT1 PF09770.4 CDI84938.1 - 5.4 5.1 72.5 9.3 4.3 50.3 1.4 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Helicase_RecD PF05127.9 CDI84939.1 - 0.46 10.0 5.6 0.17 11.5 1.8 1.7 1 1 1 2 2 2 0 Helicase Med15 PF09606.5 CDI84939.1 - 4.2 5.4 54.7 5.9 4.9 37.9 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal PPDK_N PF01326.14 CDI84941.1 - 4e-15 55.6 1.2 2e-10 40.2 0.0 4.8 3 1 0 3 3 3 2 Pyruvate phosphate dikinase, PEP/pyruvate binding domain Es2 PF09751.4 CDI84942.1 - 7.1e-10 38.8 56.9 1.8e-07 30.9 6.1 2.9 2 1 0 3 3 3 2 Nuclear protein Es2 SR-25 PF10500.4 CDI84942.1 - 0.003 17.0 20.2 0.003 17.0 14.0 5.0 5 0 0 5 5 5 3 Nuclear RNA-splicing-associated protein PAT1 PF09770.4 CDI84943.1 - 0.0036 15.6 85.1 0.0036 15.6 59.0 1.1 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 FHIPEP PF00771.15 CDI84943.1 - 0.18 10.0 32.3 0.22 9.7 22.4 1.0 1 0 0 1 1 1 0 FHIPEP family Rifin_STEVOR PF02009.11 CDI84945.1 - 0.0001 22.0 10.8 0.00012 21.8 7.5 1.0 1 0 0 1 1 1 1 Rifin/stevor family TRP PF06011.7 CDI84945.1 - 0.095 11.2 9.3 0.11 11.0 6.4 1.0 1 0 0 1 1 1 0 Transient receptor potential (TRP) ion channel PalH PF08733.5 CDI84945.1 - 0.14 10.9 4.6 0.17 10.6 3.2 1.1 1 0 0 1 1 1 0 PalH/RIM21 Sec62 PF03839.11 CDI84945.1 - 0.15 11.4 0.3 0.2 11.0 0.2 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 Neur_chan_memb PF02932.11 CDI84945.1 - 0.29 10.9 6.4 0.37 10.6 4.4 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Hid1 PF12722.2 CDI84945.1 - 0.3 8.7 21.2 0.34 8.5 14.7 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Zip PF02535.17 CDI84945.1 - 0.34 9.8 5.7 0.46 9.4 3.9 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Apt1 PF10351.4 CDI84945.1 - 0.57 8.9 24.7 0.69 8.7 17.1 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain MDFI PF15316.1 CDI84945.1 - 1.4 8.9 9.4 1.8 8.5 6.5 1.2 1 0 0 1 1 1 0 MyoD family inhibitor Tetraspannin PF00335.15 CDI84945.1 - 1.8 7.8 17.2 3.9 6.6 11.9 1.5 1 1 0 1 1 1 0 Tetraspanin family SOBP PF15279.1 CDI84945.1 - 1.9 8.8 15.2 2.3 8.4 10.6 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein DUF3807 PF12720.2 CDI84945.1 - 2.3 8.3 13.4 2.8 8.0 9.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) Utp14 PF04615.8 CDI84945.1 - 3.5 5.6 18.9 4.1 5.4 13.1 1.0 1 0 0 1 1 1 0 Utp14 protein FAM60A PF15396.1 CDI84945.1 - 3.9 7.1 13.9 5.8 6.6 9.6 1.3 1 0 0 1 1 1 0 Protein Family FAM60A DHHW PF14286.1 CDI84945.1 - 4.2 6.5 13.1 4.7 6.4 9.1 1.0 1 0 0 1 1 1 0 DHHW protein NPR3 PF03666.8 CDI84945.1 - 4.6 5.6 19.4 5.6 5.3 13.4 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF912 PF06024.7 CDI84945.1 - 4.6 7.3 28.5 0.055 13.5 8.7 2.1 1 1 1 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF566 PF04484.7 CDI84945.1 - 5.1 6.5 21.5 5.7 6.3 14.9 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF566) ABC2_membrane_3 PF12698.2 CDI84945.1 - 5.8 5.8 22.1 7.3 5.5 15.3 1.0 1 0 0 1 1 1 0 ABC-2 family transporter protein DNA_pol_viral_N PF00242.12 CDI84945.1 - 7.2 5.5 24.8 8.9 5.2 17.2 1.1 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain DFF-C PF09033.5 CDI84948.1 - 0.55 10.0 6.1 1.5 8.6 4.2 1.8 1 0 0 1 1 1 0 DNA Fragmentation factor 45kDa, C terminal domain RskA PF10099.4 CDI84950.1 - 0.0024 17.6 4.1 0.0024 17.6 2.9 17.1 9 5 4 15 15 15 2 Anti-sigma-K factor rskA IncA PF04156.9 CDI84950.1 - 0.0077 15.8 1.4 0.0077 15.8 1.0 16.9 10 4 1 11 11 11 2 IncA protein Zip PF02535.17 CDI84951.1 - 0.028 13.4 6.5 0.03 13.3 4.5 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter DUF1980 PF09323.5 CDI84951.1 - 0.029 14.1 15.6 0.04 13.6 10.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) DUF572 PF04502.8 CDI84951.1 - 0.16 11.1 19.1 0.2 10.8 13.2 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) SPX PF03105.14 CDI84951.1 - 0.29 10.8 19.9 0.37 10.5 13.8 1.1 1 0 0 1 1 1 0 SPX domain Myco_19_kDa PF05481.7 CDI84951.1 - 0.49 10.2 9.4 0.64 9.8 6.5 1.1 1 0 0 1 1 1 0 Mycobacterium 19 kDa lipoprotein antigen Herpes_DNAp_acc PF04929.7 CDI84951.1 - 0.57 9.0 17.9 0.69 8.8 12.4 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor RskA PF10099.4 CDI84951.1 - 0.7 9.6 9.2 1.5 8.5 6.4 1.4 1 1 0 1 1 1 0 Anti-sigma-K factor rskA SpoIIIAH PF12685.2 CDI84951.1 - 0.89 9.0 16.7 1.2 8.5 11.6 1.3 1 0 0 1 1 1 0 SpoIIIAH-like protein PIG-U PF06728.8 CDI84951.1 - 0.89 8.3 4.5 0.26 10.1 0.9 1.4 1 1 0 1 1 1 0 GPI transamidase subunit PIG-U DRY_EERY PF09750.4 CDI84951.1 - 1.1 9.3 11.8 2.8 8.0 0.4 2.1 2 0 0 2 2 2 0 Alternative splicing regulator TRC8_N PF13705.1 CDI84951.1 - 1.9 6.9 5.8 2.3 6.6 4.0 1.1 1 0 0 1 1 1 0 TRC8 N-terminal domain TRM13 PF05206.9 CDI84951.1 - 2.7 7.1 15.0 3.3 6.8 10.4 1.2 1 0 0 1 1 1 0 Methyltransferase TRM13 FimP PF09766.4 CDI84951.1 - 3 6.8 32.8 0.55 9.2 10.0 2.0 2 0 0 2 2 2 0 Fms-interacting protein SID-1_RNA_chan PF13965.1 CDI84951.1 - 3.6 5.6 12.5 4.2 5.4 8.7 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 X PF00739.14 CDI84951.1 - 6.3 6.7 8.4 8.6 6.2 5.8 1.2 1 0 0 1 1 1 0 Trans-activation protein X PAS PF00989.19 CDI84951.1 - 6.5 6.5 8.7 1.7 8.4 0.2 2.1 2 0 0 2 2 2 0 PAS fold GPCR_chapero_1 PF11904.3 CDI84951.1 - 9.8 5.2 17.9 12 4.9 12.4 1.0 1 0 0 1 1 1 0 GPCR-chaperone TPR_11 PF13414.1 CDI84952.1 - 3e-13 49.1 7.0 3.7e-12 45.7 0.8 2.9 1 1 2 3 3 3 2 TPR repeat TPR_14 PF13428.1 CDI84952.1 - 9.9e-06 25.7 7.6 0.055 14.1 0.0 3.6 1 1 3 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 CDI84952.1 - 1.3e-05 24.7 9.1 0.011 15.5 0.0 4.4 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.1 CDI84952.1 - 0.0014 18.7 0.2 23 5.4 0.0 3.9 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_1 PF00515.23 CDI84952.1 - 0.0016 17.9 2.0 1.4 8.6 0.0 4.1 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 CDI84952.1 - 0.0077 16.8 9.6 0.41 11.3 0.0 2.5 3 0 0 3 3 2 2 Tetratricopeptide repeat TPR_20 PF14561.1 CDI84952.1 - 0.012 15.6 2.9 0.041 13.9 1.6 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.1 CDI84952.1 - 0.014 15.7 4.5 1.3 9.4 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.1 CDI84952.1 - 0.021 14.7 0.5 0.021 14.7 0.4 2.5 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.1 CDI84952.1 - 0.11 12.3 2.3 2 8.3 0.0 2.4 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.1 CDI84952.1 - 4.2 8.0 6.8 21 5.8 0.1 3.2 4 0 0 4 4 3 0 Tetratricopeptide repeat IncA PF04156.9 CDI84953.1 - 0.00031 20.3 18.8 0.00031 20.3 13.0 4.6 2 2 1 3 3 3 1 IncA protein NfeD PF01957.13 CDI84953.1 - 1.2 9.3 7.3 8.3 6.5 2.2 2.5 2 0 0 2 2 2 0 NfeD-like C-terminal, partner-binding CD20 PF04103.10 CDI84953.1 - 2 8.3 31.6 0.8 9.6 0.4 4.7 4 1 0 4 4 4 0 CD20-like family Choline_transpo PF04515.7 CDI84953.1 - 9.4 4.8 13.4 0.42 9.2 1.5 2.7 3 0 0 3 3 3 0 Plasma-membrane choline transporter Ndc80_HEC PF03801.8 CDI84954.1 - 9.5e-30 103.1 0.0 9.5e-30 103.1 0.0 2.8 3 0 0 3 3 3 1 HEC/Ndc80p family Mnd1 PF03962.10 CDI84954.1 - 0.00093 18.9 7.0 0.00093 18.9 4.9 4.0 2 2 2 4 4 4 1 Mnd1 family zf-primase PF09329.6 CDI84955.1 - 1.5e-06 27.6 0.2 4.6e-06 26.1 0.1 1.9 1 0 0 1 1 1 1 Primase zinc finger Mcm10 PF09332.6 CDI84955.1 - 1.7e-05 24.3 28.2 1.7e-05 24.3 19.6 4.3 1 1 2 4 4 4 1 Mcm10 replication factor T2SF PF00482.18 CDI84955.1 - 0.5 10.2 3.6 0.7 9.8 0.3 2.4 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein F Plasmodium_Vir PF05795.6 CDI84955.1 - 0.92 8.6 18.0 2.5 7.2 8.3 2.3 2 0 0 2 2 2 0 Plasmodium vivax Vir protein OSTMP1 PF09777.4 CDI84956.1 - 0.18 10.9 0.0 0.26 10.4 0.0 1.2 1 0 0 1 1 1 0 Osteopetrosis-associated transmembrane protein 1 precursor Ycf1 PF05758.7 CDI84957.1 - 2.3e-08 32.2 4.1 2.3e-08 32.2 2.9 2.2 2 0 0 2 2 2 2 Ycf1 CAF-1_p150 PF11600.3 CDI84957.1 - 7.4e-05 22.2 24.2 7.4e-05 22.2 16.8 3.6 3 0 0 3 3 3 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal LMBR1 PF04791.11 CDI84957.1 - 0.015 13.8 0.1 0.015 13.8 0.1 2.2 2 1 0 2 2 2 0 LMBR1-like membrane protein Spt20 PF12090.3 CDI84958.1 - 0.01 15.1 5.7 0.011 15.0 3.9 1.2 1 0 0 1 1 1 0 Spt20 family Dynamin_N PF00350.18 CDI84958.1 - 0.074 12.8 2.4 0.077 12.8 1.7 1.2 1 0 0 1 1 1 0 Dynamin family DUF4175 PF13779.1 CDI84958.1 - 0.17 9.5 26.2 0.2 9.3 18.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) eIF3_subunit PF08597.5 CDI84958.1 - 0.18 11.3 8.3 0.19 11.2 5.8 1.1 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit PAT1 PF09770.4 CDI84958.1 - 0.34 9.1 24.2 0.38 8.9 16.8 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Topoisom_I_N PF02919.10 CDI84958.1 - 0.34 10.1 7.4 0.47 9.7 5.1 1.1 1 0 0 1 1 1 0 Eukaryotic DNA topoisomerase I, DNA binding fragment RR_TM4-6 PF06459.7 CDI84958.1 - 0.94 9.3 9.5 1.2 9.0 6.6 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Suf PF05843.9 CDI84958.1 - 1.1 8.9 11.5 1.3 8.6 8.0 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF2828 PF11443.3 CDI84958.1 - 1.1 7.3 7.3 1.3 7.1 5.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) EIIBC-GUT_N PF03612.9 CDI84958.1 - 1.1 8.8 4.7 1.4 8.4 3.3 1.2 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Band_3_cyto PF07565.8 CDI84958.1 - 1.8 7.9 8.5 2.2 7.7 5.9 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain RED_N PF07808.8 CDI84958.1 - 2.1 7.5 14.2 2.6 7.2 9.8 1.3 1 0 0 1 1 1 0 RED-like protein N-terminal region DUF4557 PF15101.1 CDI84958.1 - 2.1 8.1 14.3 2.6 7.8 9.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) DUF1501 PF07394.7 CDI84958.1 - 2.2 7.0 8.7 2.5 6.8 6.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) ATAD4 PF15321.1 CDI84958.1 - 2.2 9.3 6.6 3.4 8.7 4.6 1.3 1 0 0 1 1 1 0 ATPase family AAA domain containing 4 RAB3GAP2_N PF14655.1 CDI84958.1 - 3 6.7 10.7 3.7 6.4 7.4 1.2 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Med3 PF11593.3 CDI84958.1 - 3.7 6.6 17.5 5.5 6.1 12.1 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Serinc PF03348.10 CDI84958.1 - 4.3 5.9 7.0 5.2 5.6 4.8 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) Med15 PF09606.5 CDI84958.1 - 4.3 5.4 38.0 5.1 5.1 26.3 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF4407 PF14362.1 CDI84958.1 - 7.6 5.4 12.4 9.3 5.1 8.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Med15 PF09606.5 CDI84959.1 - 0.77 7.8 77.4 0.95 7.5 53.7 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Daxx PF03344.10 CDI84959.1 - 2.5 6.5 36.2 3.3 6.0 25.1 1.2 1 0 0 1 1 1 0 Daxx Family FCP1_C PF09309.5 CDI84960.1 - 0.011 15.1 6.7 0.011 15.1 4.7 4.3 3 1 0 3 3 3 0 FCP1, C-terminal DUF572 PF04502.8 CDI84960.1 - 0.067 12.3 68.9 0.054 12.7 25.8 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF572) TFIIF_alpha PF05793.7 CDI84960.1 - 4.2 5.6 56.1 0.092 11.1 23.6 2.6 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) PAT1 PF09770.4 CDI84962.1 - 0.0057 14.9 64.8 0.0054 15.0 44.9 1.0 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 CDC45 PF02724.9 CDI84962.1 - 0.0091 14.0 18.5 0.012 13.7 12.8 1.1 1 0 0 1 1 1 1 CDC45-like protein DUF4220 PF13968.1 CDI84962.1 - 0.037 13.1 14.3 0.046 12.8 9.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4220) Ycf1 PF05758.7 CDI84962.1 - 0.051 11.3 23.3 0.055 11.1 16.1 1.1 1 0 0 1 1 1 0 Ycf1 Utp14 PF04615.8 CDI84962.1 - 0.052 11.7 27.3 0.064 11.4 18.9 1.1 1 0 0 1 1 1 0 Utp14 protein SAPS PF04499.10 CDI84962.1 - 0.091 11.3 19.0 0.11 11.1 13.1 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF3675 PF12428.3 CDI84962.1 - 0.42 10.8 15.7 2.9 8.1 0.2 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3675) Hid1 PF12722.2 CDI84962.1 - 0.47 8.0 27.9 0.57 7.7 19.4 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Dapper PF15268.1 CDI84962.1 - 2.4 6.8 35.2 2.3 6.8 24.4 1.0 1 0 0 1 1 1 0 Dapper DUF4534 PF15049.1 CDI84962.1 - 2.7 7.5 8.7 0.17 11.5 1.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF4534) Serpentine_r_xa PF03383.10 CDI84962.1 - 3.2 7.5 6.3 8.2 6.1 0.2 2.1 1 1 1 2 2 2 0 Caenorhabditis serpentine receptor-like protein, class xa Spore_YhcN_YlaJ PF09580.5 CDI84962.1 - 3.9 7.5 31.3 0.19 11.8 0.4 2.1 2 0 0 2 2 2 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) SR-25 PF10500.4 CDI84962.1 - 5.3 6.4 28.2 8.4 5.8 15.5 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein DUF2486 PF10667.4 CDI84962.1 - 6.3 7.2 14.8 6.4 7.2 10.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2486) DUF912 PF06024.7 CDI84962.1 - 7.9 6.6 32.3 0.18 11.8 0.9 3.2 2 1 0 2 2 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Herpes_LMP2 PF07415.6 CDI84962.1 - 9.2 4.7 7.8 10 4.5 5.4 1.1 1 0 0 1 1 1 0 Gammaherpesvirus latent membrane protein (LMP2) protein YebO PF13974.1 CDI84963.1 - 4.6 7.1 5.8 12 5.8 4.0 1.6 1 1 0 1 1 1 0 YebO-like protein DUF1777 PF08648.7 CDI84965.1 - 0.00035 20.3 27.9 0.00035 20.3 19.3 3.4 3 0 0 3 3 3 3 Protein of unknown function (DUF1777) PRP38_assoc PF12871.2 CDI84965.1 - 0.00068 20.1 16.7 0.00068 20.1 11.5 3.1 3 1 0 3 3 3 1 Pre-mRNA-splicing factor 38-associated hydrophilic C-term Ribosomal_60s PF00428.14 CDI84966.1 - 0.0015 18.8 5.7 0.0015 18.8 4.0 1.2 1 0 0 1 1 1 1 60s Acidic ribosomal protein DUF2722 PF10846.3 CDI84966.1 - 0.0023 17.0 7.7 0.0028 16.7 5.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) BRF1 PF07741.8 CDI84966.1 - 0.023 14.9 2.0 0.032 14.4 1.4 1.2 1 0 0 1 1 1 0 Brf1-like TBP-binding domain Pex14_N PF04695.8 CDI84966.1 - 0.051 13.6 9.3 0.064 13.2 6.5 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Peptidase_S49_N PF08496.5 CDI84966.1 - 0.053 13.3 0.5 0.06 13.1 0.4 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal CDK5_activator PF03261.10 CDI84966.1 - 0.053 12.8 6.4 0.062 12.6 4.4 1.0 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein DUF2076 PF09849.4 CDI84966.1 - 0.084 12.9 13.3 0.11 12.5 9.2 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Hist_deacetyl PF00850.14 CDI84966.1 - 0.14 11.3 0.3 0.16 11.2 0.2 1.0 1 0 0 1 1 1 0 Histone deacetylase domain DUF3722 PF12519.3 CDI84966.1 - 0.27 10.4 1.5 0.35 10.0 1.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3722) Suf PF05843.9 CDI84966.1 - 0.38 10.4 8.6 0.42 10.3 6.0 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) CDK2AP PF09806.4 CDI84966.1 - 0.55 10.4 8.8 0.72 10.0 6.1 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein Shadoo PF14999.1 CDI84966.1 - 0.67 9.8 5.8 0.87 9.4 4.0 1.2 1 0 0 1 1 1 0 Shadow of prion protein, neuroprotective PAT1 PF09770.4 CDI84966.1 - 0.8 7.8 18.9 0.81 7.8 13.1 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 FimP PF09766.4 CDI84966.1 - 0.98 8.4 12.1 1.2 8.1 8.4 1.1 1 0 0 1 1 1 0 Fms-interacting protein Spt20 PF12090.3 CDI84966.1 - 1.7 7.9 9.8 2 7.6 6.8 1.1 1 0 0 1 1 1 0 Spt20 family Activator_LAG-3 PF11498.3 CDI84966.1 - 3 6.4 30.0 3.3 6.3 20.8 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 DUF3306 PF11748.3 CDI84966.1 - 3.6 8.2 9.4 5.5 7.6 6.5 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3306) dsDNA_bind PF01984.15 CDI84966.1 - 7.9 6.5 21.7 14 5.7 15.0 1.3 1 0 0 1 1 1 0 Double-stranded DNA-binding domain Eapp_C PF10238.4 CDI84967.1 - 2.5e-14 53.3 1.9 2.5e-14 53.3 1.3 8.3 6 3 1 7 7 7 1 E2F-associated phosphoprotein IBR PF01485.16 CDI84967.1 - 0.0021 17.8 0.8 0.007 16.2 0.1 2.3 2 0 0 2 2 2 1 IBR domain GWT1 PF06423.7 CDI84967.1 - 0.88 9.6 4.3 1.5 8.9 0.1 2.8 2 0 0 2 2 2 0 GWT1 ADK PF00406.17 CDI84968.1 - 4e-09 36.5 1.4 1.6e-07 31.2 0.0 2.6 2 1 0 2 2 2 1 Adenylate kinase Spore_coat_CotO PF14153.1 CDI84968.1 - 0.0031 16.9 8.2 0.0031 16.9 5.7 3.6 2 1 1 3 3 3 1 Spore coat protein CotO AUX_IAA PF02309.11 CDI84968.1 - 0.19 11.4 33.9 0.071 12.8 3.0 2.6 3 0 0 3 3 3 0 AUX/IAA family PAT1 PF09770.4 CDI84968.1 - 0.41 8.8 112.3 0.003 15.8 43.1 2.1 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 PCMT PF01135.14 CDI84969.1 - 2.4e-19 69.7 0.1 5.5e-19 68.5 0.0 1.6 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) RskA PF10099.4 CDI84969.1 - 0.0068 16.1 8.8 0.017 14.8 2.0 2.4 2 0 0 2 2 2 1 Anti-sigma-K factor rskA APC_CDC26 PF10471.4 CDI84969.1 - 0.83 10.4 17.9 0.43 11.3 1.5 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit 1 Dehydrin PF00257.14 CDI84969.1 - 1 9.6 7.1 1.5 9.1 1.6 2.1 2 0 0 2 2 2 0 Dehydrin DUF1635 PF07795.6 CDI84969.1 - 2.7 7.3 11.8 0.53 9.6 2.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1635) SR-25 PF10500.4 CDI84969.1 - 3.3 7.1 13.1 0.74 9.2 6.3 1.7 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein TEX13 PF15186.1 CDI84969.1 - 8.6 5.9 9.4 12 5.4 1.5 2.2 2 0 0 2 2 2 0 Testis-expressed sequence 13 protein family Arf PF00025.16 CDI84970.1 - 1.4e-21 76.5 2.1 1.9e-20 72.8 0.0 3.4 1 1 1 2 2 2 1 ADP-ribosylation factor family Miro PF08477.8 CDI84970.1 - 0.0029 18.1 9.9 0.012 16.0 0.0 3.4 3 0 0 3 3 3 1 Miro-like protein Med15 PF09606.5 CDI84970.1 - 0.0047 15.1 92.1 0.0072 14.5 63.8 1.2 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal AAA_18 PF13238.1 CDI84970.1 - 0.5 10.6 4.5 0.64 10.3 0.0 2.7 3 0 0 3 3 3 0 AAA domain zf-DHHC PF01529.15 CDI84970.1 - 2 7.7 10.4 4.9 6.5 0.2 2.6 2 0 0 2 2 2 0 DHHC palmitoyltransferase Utp14 PF04615.8 CDI84970.1 - 2.2 6.3 46.7 3.9 5.5 32.4 1.3 1 0 0 1 1 1 0 Utp14 protein OmpH PF03938.9 CDI84972.1 - 4.2e-07 30.0 0.0 4.2e-07 30.0 0.0 11.7 7 4 4 12 12 12 2 Outer membrane protein (OmpH-like) 7TM_GPCR_Srh PF10318.4 CDI84973.1 - 0.03 13.1 3.6 0.048 12.4 2.5 1.3 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srh DUF912 PF06024.7 CDI84974.1 - 0.34 10.9 0.1 0.34 10.9 0.1 4.2 2 2 2 4 4 4 0 Nucleopolyhedrovirus protein of unknown function (DUF912) IncA PF04156.9 CDI84974.1 - 2.3 7.7 36.9 0.66 9.5 9.1 3.6 3 0 0 3 3 3 0 IncA protein DUF1510 PF07423.6 CDI84975.1 - 8.6 5.6 15.9 9.3 5.5 11.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) PCEMA1 PF07418.6 CDI84976.1 - 2.1 7.6 15.4 3.4 6.9 10.6 1.3 1 0 0 1 1 1 0 Acidic phosphoprotein precursor PCEMA1 Macoilin PF09726.4 CDI84976.1 - 2.7 6.1 42.2 4.1 5.5 29.3 1.3 1 0 0 1 1 1 0 Transmembrane protein DUF4159 PF13709.1 CDI84976.1 - 4.6 6.2 10.4 7.9 5.5 7.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4159) Herpes_BLLF1 PF05109.8 CDI84976.1 - 9.6 4.0 29.5 12 3.7 20.4 1.1 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) MAR_sialic_bdg PF10564.4 CDI84977.1 - 4.2e-17 61.7 2.1 7e-17 61.0 1.5 1.3 1 0 0 1 1 1 1 Sialic-acid binding micronemal adhesive repeat MAR_sialic_bdg PF10564.4 CDI84978.1 - 9.7e-111 362.0 54.3 1.1e-21 76.4 3.6 6.1 5 1 1 6 6 6 6 Sialic-acid binding micronemal adhesive repeat zf-C3HC4_3 PF13920.1 CDI84978.1 - 1 9.1 7.5 5 6.8 0.4 3.7 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) Prenyltrans_1 PF13243.1 CDI84981.1 - 0.079 12.9 0.1 0.24 11.4 0.1 2.0 1 1 0 1 1 1 0 Prenyltransferase-like Prenyltrans PF00432.16 CDI84981.1 - 0.085 12.4 0.1 0.26 10.8 0.1 1.8 1 0 0 1 1 1 0 Prenyltransferase and squalene oxidase repeat DUF605 PF04652.11 CDI84981.1 - 0.5 9.7 14.1 0.58 9.4 9.7 1.1 1 0 0 1 1 1 0 Vta1 like Prenyltrans_2 PF13249.1 CDI84981.1 - 0.68 10.3 0.0 0.68 10.3 0.0 2.5 3 1 0 3 3 3 0 Prenyltransferase-like DUF572 PF04502.8 CDI84981.1 - 1.1 8.4 11.0 1.7 7.7 7.6 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) BRO1 PF03097.13 CDI84982.1 - 1.3e-16 60.3 3.9 1.6e-14 53.4 2.8 4.6 3 2 1 4 4 4 3 BRO1-like domain Pro_isomerase PF00160.16 CDI84984.1 - 9.3e-35 120.1 0.0 1.2e-34 119.7 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD CLAMP PF14769.1 CDI84985.1 - 2.2e-19 69.4 0.2 4.4e-19 68.5 0.2 1.5 1 0 0 1 1 1 1 Flagellar C1a complex subunit C1a-32 NRDE-2 PF08424.5 CDI84985.1 - 0.0067 15.3 2.2 0.01 14.7 1.5 1.2 1 0 0 1 1 1 1 NRDE-2, necessary for RNA interference FtsH_ext PF06480.10 CDI84985.1 - 0.023 14.8 0.0 0.097 12.8 0.0 2.0 2 0 0 2 2 2 0 FtsH Extracellular DNA_pol_B PF00136.16 CDI84986.1 - 3.1e-132 441.6 3.3 7.5e-132 440.4 2.3 1.6 1 1 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 CDI84986.1 - 5.8e-59 199.5 0.0 1.3e-58 198.4 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.1 CDI84986.1 - 9.1e-21 73.6 6.9 2e-20 72.5 4.8 1.6 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta zf-RING-like PF08746.6 CDI84986.1 - 6.6 6.8 13.0 0.51 10.3 0.6 3.3 3 0 0 3 3 3 0 RING-like domain RTX_C PF08339.5 CDI84987.1 - 1.6 8.4 12.8 2 8.1 8.8 1.1 1 0 0 1 1 1 0 RTX C-terminal domain DNA_pol_viral_N PF00242.12 CDI84987.1 - 7.8 5.4 12.0 8.6 5.2 8.3 1.0 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain Sad1_UNC PF07738.8 CDI84988.1 - 7.5e-11 41.9 3.8 1.3e-09 37.9 1.8 2.2 1 1 1 2 2 2 1 Sad1 / UNC-like C-terminal RskA PF10099.4 CDI84988.1 - 0.0011 18.8 1.4 0.0014 18.3 1.0 1.2 1 0 0 1 1 1 1 Anti-sigma-K factor rskA Virul_Fac PF10139.4 CDI84988.1 - 0.0011 17.0 0.6 0.0013 16.7 0.4 1.0 1 0 0 1 1 1 1 Putative bacterial virulence factor Dehydrin PF00257.14 CDI84988.1 - 0.0013 19.1 1.5 0.0013 19.1 1.1 3.0 2 1 0 2 2 1 1 Dehydrin DUF605 PF04652.11 CDI84988.1 - 0.0034 16.8 21.4 0.0038 16.6 14.8 1.1 1 0 0 1 1 1 1 Vta1 like Suf PF05843.9 CDI84988.1 - 0.02 14.6 19.9 0.039 13.6 13.8 1.4 1 1 0 1 1 1 0 Suppressor of forked protein (Suf) COX16 PF14138.1 CDI84988.1 - 0.05 13.7 2.2 0.084 13.0 1.5 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein COX16 TFIIA PF03153.8 CDI84988.1 - 0.064 13.1 19.9 0.073 12.9 13.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit dsDNA_bind PF01984.15 CDI84988.1 - 0.085 12.8 14.1 0.17 11.8 9.8 1.4 1 0 0 1 1 1 0 Double-stranded DNA-binding domain PAT1 PF09770.4 CDI84988.1 - 0.15 10.3 18.6 0.18 10.0 12.9 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SOBP PF15279.1 CDI84988.1 - 0.26 11.6 16.6 0.31 11.3 11.5 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein SprA-related PF12118.3 CDI84988.1 - 1.3 8.2 35.1 0.017 14.4 19.5 1.4 2 0 0 2 2 2 0 SprA-related family SAGA-Tad1 PF12767.2 CDI84988.1 - 1.7 8.2 17.4 2.2 7.8 12.0 1.2 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit OATP PF03137.15 CDI84988.1 - 1.8 6.5 13.9 1.1 7.2 2.6 2.0 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family DUF4175 PF13779.1 CDI84988.1 - 5 4.6 19.4 7.1 4.1 13.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) AIF_C PF14721.1 CDI84988.1 - 6 7.1 10.6 2.8 8.1 1.4 2.2 2 0 0 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term PHD_3 PF13922.1 CDI84988.1 - 9.8 6.4 13.3 0.64 10.2 4.5 2.3 2 1 0 2 2 2 0 PHD domain of transcriptional enhancer, Asx SAPS PF04499.10 CDI84989.1 - 0.82 8.2 10.0 0.65 8.5 6.1 1.4 1 1 0 1 1 1 0 SIT4 phosphatase-associated protein LRR_6 PF13516.1 CDI84990.1 - 0.00078 19.2 0.0 0.21 11.7 0.0 3.1 2 0 0 2 2 2 1 Leucine Rich repeat SR-25 PF10500.4 CDI84990.1 - 0.00087 18.8 14.0 0.00087 18.8 9.7 13.3 7 4 4 12 12 12 2 Nuclear RNA-splicing-associated protein DUF3357 PF11837.3 CDI84991.1 - 0.029 14.2 0.8 0.029 14.2 0.5 2.2 3 0 0 3 3 3 0 Domain of unknown function (DUF3357) Ribosomal_60s PF00428.14 CDI84991.1 - 0.14 12.5 38.7 0.13 12.6 4.4 3.2 3 0 0 3 3 3 0 60s Acidic ribosomal protein EF-hand_2 PF09068.6 CDI84991.1 - 0.28 11.2 11.3 1.9 8.5 1.7 2.3 2 1 0 2 2 2 0 EF hand ABC2_membrane_2 PF12679.2 CDI84991.1 - 0.34 9.7 4.6 0.32 9.8 1.0 2.1 2 0 0 2 2 2 0 ABC-2 family transporter protein Tmemb_9 PF05434.6 CDI84991.1 - 0.35 10.6 0.0 0.35 10.6 0.0 2.9 2 1 1 3 3 3 0 TMEM9 Shadoo PF14999.1 CDI84991.1 - 0.95 9.3 23.4 0.14 12.0 0.8 3.2 3 0 0 3 3 3 0 Shadow of prion protein, neuroprotective DUF1275 PF06912.6 CDI84991.1 - 1.1 8.3 9.2 0.16 11.1 2.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1275) AzlD PF05437.7 CDI84991.1 - 1.3 9.0 7.9 0.18 11.7 0.9 2.5 2 0 0 2 2 2 0 Branched-chain amino acid transport protein (AzlD) RskA PF10099.4 CDI84991.1 - 4.8 6.8 38.1 0.038 13.7 5.5 3.2 2 1 0 3 3 3 0 Anti-sigma-K factor rskA N6_N4_Mtase PF01555.13 CDI84992.1 - 9.3e-06 25.2 0.2 27 4.1 0.0 5.6 3 3 0 3 3 3 2 DNA methylase Cwf_Cwc_15 PF04889.7 CDI84994.1 - 0.023 14.4 17.2 0.032 13.9 11.9 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein B12D PF06522.6 CDI84994.1 - 0.027 14.1 0.6 0.16 11.6 0.0 2.5 2 1 1 3 3 3 0 NADH-ubiquinone reductase complex 1 MLRQ subunit SOBP PF15279.1 CDI84994.1 - 0.24 11.7 24.7 0.32 11.3 17.1 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein FUSC PF04632.7 CDI84994.1 - 1.2 7.4 37.8 1.5 7.1 26.2 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family Herpes_UL87 PF03043.9 CDI84994.1 - 3.6 5.8 19.3 4.5 5.5 13.4 1.0 1 0 0 1 1 1 0 Herpesvirus UL87 family TraT PF05818.7 CDI84994.1 - 8.1 5.7 19.3 0.57 9.5 6.4 2.1 2 0 0 2 2 2 0 Enterobacterial TraT complement resistance protein Ribosomal_S25 PF03297.10 CDI84995.1 - 8.7e-42 141.4 0.7 9.7e-42 141.2 0.5 1.0 1 0 0 1 1 1 1 S25 ribosomal protein HTH_27 PF13463.1 CDI84995.1 - 0.061 13.6 0.0 0.12 12.6 0.0 1.6 2 0 0 2 2 2 0 Winged helix DNA-binding domain MarR_2 PF12802.2 CDI84995.1 - 0.084 12.5 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 MarR family Rrf2 PF02082.15 CDI84995.1 - 0.094 12.8 0.0 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 Transcriptional regulator Trp_halogenase PF04820.9 CDI84995.1 - 0.13 10.9 0.1 0.14 10.7 0.1 1.1 1 0 0 1 1 1 0 Tryptophan halogenase BAF1_ABF1 PF04684.8 CDI84997.1 - 0.0062 15.4 10.6 0.0077 15.1 7.3 1.0 1 0 0 1 1 1 1 BAF1 / ABF1 chromatin reorganising factor PRCC PF10253.4 CDI84997.1 - 0.041 14.5 1.5 0.051 14.2 1.0 1.2 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting E_Pc_C PF06752.7 CDI84997.1 - 0.044 13.2 13.1 0.058 12.8 9.1 1.2 1 0 0 1 1 1 0 Enhancer of Polycomb C-terminus Phage_int_SAM_2 PF12834.2 CDI84997.1 - 0.046 14.1 1.3 0.051 13.9 0.9 1.2 1 0 0 1 1 1 0 Phage integrase, N-terminal Neuro_bHLH PF12533.3 CDI84997.1 - 0.057 14.2 0.8 0.061 14.1 0.6 1.0 1 0 0 1 1 1 0 Neuronal helix-loop-helix transcription factor Med15 PF09606.5 CDI84997.1 - 0.059 11.5 7.5 0.058 11.5 5.2 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Blt1 PF12754.2 CDI84997.1 - 0.083 12.4 0.5 0.089 12.3 0.3 1.1 1 0 0 1 1 1 0 Cell-cycle control medial ring component SLT_2 PF13406.1 CDI84997.1 - 0.12 11.2 2.9 0.14 11.0 2.0 1.0 1 0 0 1 1 1 0 Transglycosylase SLT domain DUF2620 PF10941.3 CDI84997.1 - 0.18 11.8 2.6 0.21 11.6 1.8 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF2620 CDK2AP PF09806.4 CDI84997.1 - 0.39 10.9 4.9 0.57 10.3 3.4 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein DUF3138 PF11336.3 CDI84997.1 - 0.87 7.6 12.7 0.9 7.6 8.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) DUF4557 PF15101.1 CDI84997.1 - 1.2 8.9 6.2 1.3 8.7 4.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) EII-Sor PF03609.9 CDI84998.1 - 0.41 9.8 2.9 0.53 9.5 2.0 1.3 1 0 0 1 1 1 0 PTS system sorbose-specific iic component Med15 PF09606.5 CDI84998.1 - 1.5 6.9 17.7 1.7 6.7 12.3 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal rve PF00665.21 CDI84999.1 - 1.6e-16 60.4 0.0 5.1e-16 58.8 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 CDI84999.1 - 3.3e-11 42.9 0.0 7.8e-11 41.7 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Chromo PF00385.19 CDI84999.1 - 2.4e-09 36.7 0.1 5.3e-09 35.6 0.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-H2C2 PF09337.5 CDI84999.1 - 0.036 13.4 0.6 0.067 12.6 0.4 1.4 1 0 0 1 1 1 0 His(2)-Cys(2) zinc finger gag-asp_proteas PF13975.1 CDI85000.1 - 9.5e-10 38.1 0.1 3.2e-09 36.4 0.0 1.9 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 CDI85000.1 - 1.2e-06 28.8 0.0 2.8e-06 27.7 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.6 CDI85000.1 - 0.0008 19.3 0.0 0.074 12.9 0.0 2.4 1 1 0 2 2 2 1 Retroviral aspartyl protease RVP PF00077.15 CDI85000.1 - 0.0051 16.7 0.0 0.016 15.1 0.0 1.8 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.5 CDI85000.1 - 0.024 14.2 0.0 0.42 10.1 0.0 2.1 1 1 1 2 2 2 0 Aspartyl protease COX7a PF02238.10 CDI85000.1 - 0.047 13.4 0.0 0.098 12.3 0.0 1.5 1 0 0 1 1 1 0 Cytochrome c oxidase subunit VIIa Caldesmon PF02029.10 CDI85003.1 - 0.0018 16.7 25.9 0.0018 16.7 18.0 2.1 2 0 0 2 2 2 1 Caldesmon PAT1 PF09770.4 CDI85003.1 - 6.5 4.8 96.0 7.4 4.6 66.6 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SR-25 PF10500.4 CDI85003.1 - 7.7 5.9 52.4 0.2 11.0 3.4 3.2 3 0 0 3 3 3 0 Nuclear RNA-splicing-associated protein DUF3469 PF11952.3 CDI85005.1 - 0.0015 18.1 0.0 0.0025 17.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3469) MSP1_C PF07462.6 CDI85005.1 - 4.8 5.4 12.5 6.1 5.1 8.6 1.2 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus DUF3357 PF11837.3 CDI85006.1 - 0.0026 17.5 3.6 0.043 13.6 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF3357) PSII_Ycf12 PF05969.6 CDI85006.1 - 0.0073 15.9 2.2 0.011 15.3 1.6 1.2 1 0 0 1 1 1 1 Photosystem II complex subunit Ycf12 PSK PF06404.7 CDI85006.1 - 0.095 13.4 8.3 4.6 8.0 2.6 2.3 2 0 0 2 2 2 0 Phytosulfokine precursor protein (PSK) DUF1764 PF08576.5 CDI85006.1 - 0.12 13.1 19.0 0.86 10.4 0.1 2.1 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF1764) Zip PF02535.17 CDI85006.1 - 0.16 10.9 2.6 0.19 10.6 1.8 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Peroxin-13_N PF04088.8 CDI85006.1 - 0.16 11.9 8.1 0.49 10.3 2.2 2.1 2 0 0 2 2 2 0 Peroxin 13, N-terminal region DUF177 PF02620.12 CDI85006.1 - 0.16 12.0 9.8 0.52 10.3 6.8 1.8 1 1 0 1 1 1 0 Uncharacterized ACR, COG1399 Ctr PF04145.10 CDI85006.1 - 0.21 11.6 11.4 2.9 7.9 4.8 2.2 2 0 0 2 2 2 0 Ctr copper transporter family DHHW PF14286.1 CDI85006.1 - 0.23 10.7 9.7 0.27 10.4 6.7 1.1 1 0 0 1 1 1 0 DHHW protein RNA_pol_Rpb1_5 PF04998.12 CDI85006.1 - 0.24 10.6 5.9 0.33 10.1 4.1 1.2 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 FimP PF09766.4 CDI85006.1 - 0.26 10.3 38.9 0.13 11.2 4.2 2.0 2 0 0 2 2 2 0 Fms-interacting protein Neur_chan_memb PF02932.11 CDI85006.1 - 0.28 11.0 9.5 0.37 10.6 6.6 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region PH_4 PF15404.1 CDI85006.1 - 0.3 10.6 17.1 2.8 7.4 7.9 2.1 2 0 0 2 2 2 0 Pleckstrin homology domain NinG PF05766.7 CDI85006.1 - 0.38 10.4 19.2 2.5 7.8 9.2 2.1 2 0 0 2 2 2 0 Bacteriophage Lambda NinG protein FAM176 PF14851.1 CDI85006.1 - 0.43 10.2 10.1 6.3 6.4 0.1 2.1 2 0 0 2 2 2 0 FAM176 family Tau95 PF09734.4 CDI85006.1 - 0.47 9.7 7.4 0.53 9.5 5.1 1.1 1 0 0 1 1 1 0 RNA polymerase III transcription factor (TF)IIIC subunit AIF_C PF14721.1 CDI85006.1 - 0.56 10.4 13.8 6 7.1 0.1 2.1 2 0 0 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term FYDLN_acid PF09538.5 CDI85006.1 - 0.7 10.5 7.4 6.8 7.3 2.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) DUF3408 PF11888.3 CDI85006.1 - 0.76 9.7 16.8 2.4 8.1 5.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3408) RIC3 PF15361.1 CDI85006.1 - 0.84 9.8 16.0 2.8 8.1 5.1 2.1 2 0 0 2 2 2 0 Resistance to inhibitors of cholinesterase homologue 3 DUF4175 PF13779.1 CDI85006.1 - 0.97 7.0 51.1 0.41 8.2 8.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4175) RNA_pol_Rbc25 PF08292.7 CDI85006.1 - 0.97 9.6 14.4 1.1 9.4 0.4 2.1 2 0 0 2 2 2 0 RNA polymerase III subunit Rpc25 Peptidase_S49_N PF08496.5 CDI85006.1 - 0.98 9.1 17.4 2.7 7.7 0.1 2.2 2 0 0 2 2 2 0 Peptidase family S49 N-terminal HA2 PF04408.18 CDI85006.1 - 0.99 9.4 5.8 11 6.0 0.0 2.1 2 0 0 2 2 2 0 Helicase associated domain (HA2) eIF_4EBP PF05456.6 CDI85006.1 - 1.1 8.9 14.6 2.4 7.8 4.3 2.2 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) Serinc PF03348.10 CDI85006.1 - 1.1 7.8 17.5 1.7 7.2 6.2 2.0 2 0 0 2 2 2 0 Serine incorporator (Serinc) zf-DHHC PF01529.15 CDI85006.1 - 1.1 8.5 15.3 0.74 9.1 0.6 2.1 2 0 0 2 2 2 0 DHHC palmitoyltransferase Afaf PF15339.1 CDI85006.1 - 1.3 8.5 6.5 10 5.6 2.3 2.1 2 0 0 2 2 2 0 Acrosome formation-associated factor Dala_Dala_lig_N PF01820.16 CDI85006.1 - 1.3 9.3 9.4 6.8 7.0 3.2 2.1 2 0 0 2 2 2 0 D-ala D-ala ligase N-terminus GRP PF07172.6 CDI85006.1 - 1.4 9.4 6.1 4.1 7.9 0.1 2.2 2 0 0 2 2 2 0 Glycine rich protein family Presenilin PF01080.12 CDI85006.1 - 1.4 7.6 8.0 1.8 7.2 5.5 1.1 1 0 0 1 1 1 0 Presenilin OPA3 PF07047.7 CDI85006.1 - 1.5 8.6 14.5 1.8 8.3 4.7 2.1 2 0 0 2 2 2 0 Optic atrophy 3 protein (OPA3) tRNA_synt_1c_R2 PF04557.10 CDI85006.1 - 2.2 9.0 11.0 8.7 7.1 0.0 2.2 2 0 0 2 2 2 0 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 Eapp_C PF10238.4 CDI85006.1 - 2.4 8.0 14.7 4.3 7.2 0.2 2.1 2 0 0 2 2 2 0 E2F-associated phosphoprotein PCYCGC PF13798.1 CDI85006.1 - 2.8 7.5 11.0 1.4 8.5 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function with PCYCGC motif OATP PF03137.15 CDI85006.1 - 3.1 5.7 15.9 1.8 6.5 0.2 2.0 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family DUF3306 PF11748.3 CDI85006.1 - 3.3 8.3 18.4 4.2 8.0 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3306) DUF4064 PF13273.1 CDI85006.1 - 3.4 7.8 8.1 1.5 8.9 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) HNOBA PF07701.9 CDI85006.1 - 3.7 6.7 16.4 4.6 6.3 0.8 2.1 2 0 0 2 2 2 0 Heme NO binding associated Gti1_Pac2 PF09729.4 CDI85006.1 - 3.8 7.3 12.6 14 5.5 5.3 2.1 2 0 0 2 2 2 0 Gti1/Pac2 family Pex16 PF08610.5 CDI85006.1 - 4 6.3 20.7 1.2 8.0 1.0 2.1 2 0 0 2 2 2 0 Peroxisomal membrane protein (Pex16) CD20 PF04103.10 CDI85006.1 - 4.7 7.1 11.9 1.8 8.4 0.1 2.1 2 0 0 2 2 2 0 CD20-like family NYN_YacP PF05991.6 CDI85006.1 - 5.4 6.7 15.9 8.8 6.0 6.7 2.1 2 0 0 2 2 2 0 YacP-like NYN domain Trp_oprn_chp PF09534.5 CDI85006.1 - 5.6 6.5 6.1 5.5 6.5 0.0 2.0 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) LIM_bind PF01803.11 CDI85006.1 - 5.6 5.9 26.1 1.1 8.3 2.2 2.0 2 0 0 2 2 2 0 LIM-domain binding protein ATAD4 PF15321.1 CDI85006.1 - 5.6 8.0 20.7 4.5 8.3 0.6 2.1 2 0 0 2 2 2 0 ATPase family AAA domain containing 4 DUF2140 PF09911.4 CDI85006.1 - 6.5 5.8 10.6 1.6 7.8 0.2 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2140) DUF979 PF06166.7 CDI85006.1 - 8.1 5.2 7.0 0.49 9.3 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF979) CagX PF03524.10 CDI85006.1 - 8.2 5.6 19.1 1.7 7.8 0.7 2.1 2 0 0 2 2 2 0 Conjugal transfer protein Zn_peptidase PF04228.8 CDI85006.1 - 8.7 5.4 20.2 0.9 8.7 2.1 2.1 2 0 0 2 2 2 0 Putative neutral zinc metallopeptidase Spore_coat_CotO PF14153.1 CDI85006.1 - 8.9 5.7 29.8 1 8.7 2.3 2.1 2 0 0 2 2 2 0 Spore coat protein CotO G0-G1_switch_2 PF15103.1 CDI85006.1 - 9.1 6.5 18.8 9.5 6.5 0.6 2.2 2 0 0 2 2 2 0 G0/G1 switch protein 2 DUF3474 PF11960.3 CDI85006.1 - 9.4 6.2 9.0 15 5.5 0.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3474) PBP1_TM PF14812.1 CDI85006.1 - 9.6 6.5 10.7 20 5.5 3.5 2.2 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CAF-1_p150 PF11600.3 CDI85007.1 - 0.23 10.8 26.7 0.57 9.5 11.7 2.2 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DNA_pol_A_exo1 PF01612.15 CDI85009.1 - 3.4e-32 111.3 0.0 4.8e-32 110.8 0.0 1.2 1 0 0 1 1 1 1 3'-5' exonuclease Suf PF05843.9 CDI85011.1 - 0.0081 15.9 4.8 0.0069 16.1 3.3 1.1 1 0 0 1 1 1 1 Suppressor of forked protein (Suf) FPN1 PF06963.7 CDI85011.1 - 0.019 13.3 0.5 0.028 12.8 0.3 1.2 1 0 0 1 1 1 0 Ferroportin1 (FPN1) Med15 PF09606.5 CDI85011.1 - 0.02 13.1 32.2 0.03 12.5 22.3 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal FimP PF09766.4 CDI85011.1 - 0.029 13.4 10.1 0.033 13.2 7.0 1.1 1 0 0 1 1 1 0 Fms-interacting protein Spt20 PF12090.3 CDI85011.1 - 0.041 13.2 3.7 0.044 13.1 2.6 1.2 1 0 0 1 1 1 0 Spt20 family DDHD PF02862.12 CDI85011.1 - 0.18 11.5 4.4 0.23 11.2 3.1 1.2 1 0 0 1 1 1 0 DDHD domain Serinc PF03348.10 CDI85011.1 - 0.24 10.0 4.7 0.26 9.9 3.3 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) Mif2_N PF15624.1 CDI85011.1 - 0.74 10.4 6.0 0.94 10.0 4.1 1.2 1 0 0 1 1 1 0 Kinetochore CENP-C fungal homologue, Mif2, N-terminal TFIIA PF03153.8 CDI85011.1 - 2.5 7.9 23.7 3 7.6 16.4 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Pup PF05639.6 CDI85011.1 - 7.9 7.0 14.7 3.7 8.1 8.0 2.0 2 0 0 2 2 2 0 Pup-like protein EphA2_TM PF14575.1 CDI85012.1 - 5.3e-07 29.9 3.6 0.15 12.5 0.1 3.5 1 1 3 4 4 3 2 Ephrin type-A receptor 2 transmembrane domain Conotoxin PF02950.12 CDI85012.1 - 4.7e-06 27.3 11.4 0.004 17.9 0.1 3.5 1 1 3 4 4 4 2 Conotoxin DUF3515 PF12028.3 CDI85012.1 - 9.2e-05 21.7 0.5 0.27 10.4 0.1 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF3515) DUF3357 PF11837.3 CDI85012.1 - 0.00012 21.8 0.1 0.26 11.1 0.0 2.5 1 1 2 3 3 3 2 Domain of unknown function (DUF3357) DUF1345 PF07077.6 CDI85012.1 - 0.00051 19.6 0.3 0.82 9.1 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1345) Gastrin PF00918.12 CDI85012.1 - 0.0018 19.0 2.3 1.5 9.6 0.0 2.7 2 1 0 2 2 2 2 Gastrin/cholecystokinin family DUF4245 PF14030.1 CDI85012.1 - 0.0021 17.8 0.4 2.1 8.0 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF4245) Salp15 PF12115.3 CDI85012.1 - 0.0024 18.0 3.4 3.6 7.8 0.2 3.2 1 1 2 3 3 3 1 Salivary protein of 15kDa inhibits CD4+ T cell activation Baculo_11_kDa PF06143.6 CDI85012.1 - 0.003 16.8 5.9 2.6 7.4 0.4 3.4 2 1 1 3 3 3 1 Baculovirus 11 kDa family DUF1183 PF06682.7 CDI85012.1 - 0.006 16.2 0.3 2.4 7.7 0.0 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF1183) DUF3836 PF12930.2 CDI85012.1 - 0.0066 15.9 0.9 2.9 7.3 0.1 2.3 2 0 0 2 2 2 2 Family of unknown function (DUF3836) DUF2140 PF09911.4 CDI85012.1 - 0.0092 15.1 1.4 3 6.9 0.1 2.7 1 1 2 3 3 3 1 Uncharacterized protein conserved in bacteria (DUF2140) SDA1 PF05285.7 CDI85012.1 - 0.011 14.9 41.2 0.015 14.6 28.6 1.1 1 0 0 1 1 1 0 SDA1 Herpes_US9 PF06072.6 CDI85012.1 - 0.014 15.1 0.3 1.6 8.6 0.0 2.4 2 0 0 2 2 2 0 Alphaherpesvirus tegument protein US9 DUF2637 PF10935.3 CDI85012.1 - 0.015 15.2 0.2 3.8 7.4 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2637) Spore_YtfJ PF09579.5 CDI85012.1 - 0.017 14.9 0.1 6.1 6.7 0.0 2.2 2 0 0 2 2 2 0 Sporulation protein YtfJ (Spore_YtfJ) SSF PF00474.12 CDI85012.1 - 0.021 13.4 5.3 0.83 8.2 0.2 2.0 2 0 0 2 2 2 0 Sodium:solute symporter family tRNA_anti-like PF12869.2 CDI85012.1 - 0.029 13.8 0.5 5.3 6.5 0.0 2.2 1 1 1 2 2 2 0 tRNA_anti-like DUF3311 PF11755.3 CDI85012.1 - 0.056 12.9 0.0 18 4.9 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3311) JHBP PF06585.6 CDI85012.1 - 0.063 12.0 0.0 8 5.1 0.0 2.0 2 0 0 2 2 2 0 Haemolymph juvenile hormone binding protein (JHBP) 7tm_1 PF00001.16 CDI85012.1 - 0.074 12.1 0.1 0.22 10.6 0.1 1.7 1 1 1 2 2 2 0 7 transmembrane receptor (rhodopsin family) Stig1 PF04885.8 CDI85012.1 - 0.084 13.0 0.8 11 6.2 0.1 2.4 1 1 2 3 3 3 0 Stigma-specific protein, Stig1 COX6A PF02046.10 CDI85012.1 - 0.11 12.4 7.3 1.4 8.8 0.6 2.3 2 0 0 2 2 2 0 Cytochrome c oxidase subunit VIa Tweety PF04906.8 CDI85012.1 - 0.13 10.6 0.0 6.4 5.0 0.0 2.4 2 0 0 2 2 2 0 Tweety PCYCGC PF13798.1 CDI85012.1 - 0.17 11.5 8.4 1.1 8.9 0.8 2.4 2 1 0 2 2 2 0 Protein of unknown function with PCYCGC motif PUCC PF03209.10 CDI85012.1 - 0.43 9.2 3.2 4.8 5.7 0.1 2.1 2 0 0 2 2 2 0 PUCC protein DUF1686 PF07937.6 CDI85012.1 - 0.43 10.1 9.7 1.9 8.0 0.2 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF1686) Bd3614_N PF14442.1 CDI85012.1 - 0.45 10.4 17.9 1.4 8.9 3.5 2.2 2 0 0 2 2 2 0 Bd3614-like deaminase N-terminal DUF2500 PF10694.4 CDI85012.1 - 0.59 10.1 4.5 2.3 8.2 0.1 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2500) SGT1 PF07093.6 CDI85012.1 - 0.65 8.2 25.5 0.81 7.9 17.7 1.0 1 0 0 1 1 1 0 SGT1 protein DUF3169 PF11368.3 CDI85012.1 - 0.68 9.0 13.7 0.23 10.6 1.0 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF3169) Herpes_UL49_5 PF05702.6 CDI85012.1 - 1.7 8.5 7.0 9.1 6.2 0.4 2.3 1 1 1 2 2 2 0 Herpesvirus UL49.5 envelope/tegument protein Serinc PF03348.10 CDI85012.1 - 2 7.0 5.8 22 3.5 4.0 2.0 1 1 0 1 1 1 0 Serine incorporator (Serinc) DUF2457 PF10446.4 CDI85012.1 - 3.9 6.1 55.9 3 6.4 14.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) FHIPEP PF00771.15 CDI85012.1 - 4.6 5.4 9.2 5.8 5.1 0.9 2.2 1 1 1 2 2 2 0 FHIPEP family Dpy19 PF10034.4 CDI85012.1 - 5.1 5.1 5.1 47 1.9 3.5 2.0 1 1 0 1 1 1 0 Q-cell neuroblast polarisation Chordopox_A13L PF05961.6 CDI85012.1 - 5.2 7.0 8.3 9.8 6.1 0.3 3.0 1 1 3 4 4 3 0 Chordopoxvirus A13L protein SEFIR PF08357.6 CDI85012.1 - 5.5 7.0 6.7 3.8 7.5 0.5 2.2 1 1 1 2 2 2 0 SEFIR domain Spt20 PF12090.3 CDI85013.1 - 0.00027 20.3 10.7 0.028 13.7 0.8 2.4 2 0 0 2 2 2 2 Spt20 family Serinc PF03348.10 CDI85013.1 - 0.013 14.2 11.8 0.14 10.8 1.3 2.3 2 0 0 2 2 2 0 Serine incorporator (Serinc) MAT1 PF06391.8 CDI85013.1 - 0.29 10.6 21.6 0.24 10.9 6.1 2.2 2 0 0 2 2 2 0 CDK-activating kinase assembly factor MAT1 Activator_LAG-3 PF11498.3 CDI85013.1 - 0.34 9.6 45.6 0.14 10.8 13.6 2.7 2 0 0 2 2 2 0 Transcriptional activator LAG-3 Coiled-coil_56 PF09813.4 CDI85013.1 - 1.3 9.1 10.5 1.2 9.1 1.1 2.7 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 56 CAF-1_p150 PF11600.3 CDI85014.1 - 0.014 14.8 10.7 0.014 14.8 7.4 2.0 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal CDC45 PF02724.9 CDI85014.1 - 0.61 8.0 13.7 0.89 7.5 9.5 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF4358 PF14270.1 CDI85014.1 - 3 7.7 9.9 22 5.0 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4358) SR-25 PF10500.4 CDI85014.1 - 5.1 6.4 24.1 0.069 12.6 11.2 1.8 2 1 0 2 2 2 0 Nuclear RNA-splicing-associated protein DUF3729 PF12526.3 CDI85014.1 - 7.5 7.9 13.4 2.8 9.3 5.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3729) SseC PF04888.7 CDI85015.1 - 0.0026 17.1 26.2 0.0026 17.1 18.2 2.4 2 0 0 2 2 2 1 Secretion system effector C (SseC) like family SR-25 PF10500.4 CDI85015.1 - 0.088 12.2 6.1 0.13 11.7 4.3 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein FliL PF03748.9 CDI85015.1 - 0.095 12.7 6.8 1.1 9.2 4.4 2.2 2 0 0 2 2 2 0 Flagellar basal body-associated protein FliL DUF4404 PF14357.1 CDI85015.1 - 0.31 11.4 17.0 0.11 12.9 8.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) YjgP_YjgQ PF03739.9 CDI85015.1 - 0.49 9.0 2.4 0.58 8.8 1.7 1.1 1 0 0 1 1 1 0 Predicted permease YjgP/YjgQ family Med15 PF09606.5 CDI85015.1 - 0.9 7.6 53.1 1.5 6.8 36.8 1.3 1 1 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal YkuI_C PF10388.4 CDI85015.1 - 1.2 8.7 9.8 0.55 9.8 5.4 1.4 2 0 0 2 2 2 0 EAL-domain associated signalling protein domain AAA_23 PF13476.1 CDI85015.1 - 1.3 9.2 15.2 1.9 8.7 10.6 1.2 1 0 0 1 1 1 0 AAA domain Glyco_transf_29 PF00777.13 CDI85015.1 - 2 7.4 8.6 3.5 6.7 6.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase family 29 (sialyltransferase) HlyD_2 PF12700.2 CDI85015.1 - 2.4 7.2 7.9 2.8 7.0 5.5 1.2 1 0 0 1 1 1 0 HlyD family secretion protein Tctex-1 PF03645.8 CDI85015.1 - 2.7 7.8 7.6 0.83 9.5 2.9 1.8 2 0 0 2 2 2 0 Tctex-1 family Serinc PF03348.10 CDI85015.1 - 5.1 5.7 9.2 6.7 5.3 6.4 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) DUF3573 PF12097.3 CDI85015.1 - 10 4.6 7.9 14 4.2 5.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) Folate_carrier PF01770.13 CDI85016.1 - 0.21 10.0 4.8 0.35 9.3 3.3 1.4 1 0 0 1 1 1 0 Reduced folate carrier OATP PF03137.15 CDI85016.1 - 1.3 6.9 8.3 1.8 6.4 5.7 1.3 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Med15 PF09606.5 CDI85016.1 - 3.1 5.8 44.6 3.9 5.5 30.9 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Mem_trans PF03547.13 CDI85016.1 - 4.7 5.4 5.8 7.5 4.7 4.0 1.3 1 0 0 1 1 1 0 Membrane transport protein MIP-T3 PF10243.4 CDI85017.1 - 4.8e-05 22.0 21.7 4.8e-05 22.0 15.0 4.7 5 0 0 5 5 5 2 Microtubule-binding protein MIP-T3 PAP_assoc PF03828.14 CDI85017.1 - 0.0004 20.2 0.1 0.012 15.5 0.1 2.6 2 0 0 2 2 2 1 Cid1 family poly A polymerase DAHP_synth_2 PF01474.11 CDI85018.1 - 1.4e-28 99.4 0.0 1.7e-28 99.2 0.0 1.0 1 0 0 1 1 1 1 Class-II DAHP synthetase family YicC_N PF03755.8 CDI85019.1 - 0.12 12.3 3.2 7.1 6.5 2.2 2.5 1 1 0 1 1 1 0 YicC-like family, N-terminal region Intron_maturas2 PF01348.16 CDI85019.1 - 0.24 11.3 2.6 1 9.3 1.8 1.9 1 1 0 1 1 1 0 Type II intron maturase DUF1280 PF06918.9 CDI85019.1 - 0.26 10.4 6.7 0.73 8.9 4.6 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1280) PAT1 PF09770.4 CDI85021.1 - 0.043 12.0 43.1 0.049 11.8 29.9 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Utp14 PF04615.8 CDI85021.1 - 0.3 9.2 33.0 0.33 9.0 22.9 1.1 1 0 0 1 1 1 0 Utp14 protein Plasmodium_Vir PF05795.6 CDI85021.1 - 1.4 8.0 25.1 2.7 7.0 17.4 1.5 1 0 0 1 1 1 0 Plasmodium vivax Vir protein SseC PF04888.7 CDI85024.1 - 0.0047 16.3 5.5 0.0047 16.3 3.8 7.9 6 2 1 7 7 7 2 Secretion system effector C (SseC) like family Suf PF05843.9 CDI85024.1 - 0.02 14.6 42.2 0.23 11.1 3.5 4.5 4 0 0 4 4 4 0 Suppressor of forked protein (Suf) DUF3801 PF12687.2 CDI85024.1 - 1.7 8.1 40.7 0.0072 15.9 7.3 3.7 4 0 0 4 4 4 0 Protein of unknown function (DUF3801) OmpH PF03938.9 CDI85025.1 - 0.0018 18.2 6.4 0.0024 17.8 4.4 1.2 1 0 0 1 1 1 1 Outer membrane protein (OmpH-like) IncA PF04156.9 CDI85025.1 - 0.0024 17.5 4.6 0.0042 16.6 3.2 1.3 1 0 0 1 1 1 1 IncA protein Activator_LAG-3 PF11498.3 CDI85025.1 - 0.041 12.6 15.9 0.063 12.0 11.0 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 TFIIA PF03153.8 CDI85025.1 - 0.096 12.5 7.6 0.17 11.7 5.3 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit TALPID3 PF15324.1 CDI85025.1 - 1.1 6.5 7.0 1.6 5.9 4.8 1.2 1 0 0 1 1 1 0 Hedgehog signalling target DUF3617 PF12276.3 CDI85025.1 - 1.3 8.4 9.1 2.3 7.6 6.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3617) Ctr PF04145.10 CDI85025.1 - 1.3 9.0 4.3 0.62 10.1 1.3 1.7 2 0 0 2 2 2 0 Ctr copper transporter family DUF3373 PF11853.3 CDI85025.1 - 2.6 6.4 4.2 3.8 5.9 2.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) Ribosomal_60s PF00428.14 CDI85026.1 - 0.029 14.7 27.5 0.099 13.0 6.8 3.0 3 0 0 3 3 3 0 60s Acidic ribosomal protein Pap_E4 PF02711.9 CDI85026.1 - 0.058 14.2 6.9 0.045 14.5 2.4 2.3 2 0 0 2 2 2 0 E4 protein Peptidase_M16_C PF05193.16 CDI85026.1 - 0.27 10.9 1.6 2.1 8.0 0.0 2.3 2 0 0 2 2 2 0 Peptidase M16 inactive domain zf-DHHC PF01529.15 CDI85027.1 - 0.21 10.9 11.2 0.59 9.5 0.4 2.2 2 0 0 2 2 2 0 DHHC palmitoyltransferase Zn_peptidase PF04228.8 CDI85027.1 - 0.6 9.2 19.0 1.4 8.0 4.2 2.3 2 0 0 2 2 2 0 Putative neutral zinc metallopeptidase Plasmodium_Vir PF05795.6 CDI85027.1 - 1.7 7.7 7.8 4.8 6.2 0.4 2.2 2 0 0 2 2 2 0 Plasmodium vivax Vir protein D123 PF07065.9 CDI85027.1 - 2 7.4 15.8 2.5 7.0 2.4 2.3 2 0 0 2 2 2 0 D123 RAB3GAP2_N PF14655.1 CDI85027.1 - 2 7.3 22.6 3.4 6.5 5.1 2.5 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Pex16 PF08610.5 CDI85027.1 - 2.9 6.8 18.7 1.4 7.8 3.3 2.3 2 0 0 2 2 2 0 Peroxisomal membrane protein (Pex16) Topoisom_I_N PF02919.10 CDI85027.1 - 3.6 6.8 12.0 0.98 8.6 0.4 2.2 2 0 0 2 2 2 0 Eukaryotic DNA topoisomerase I, DNA binding fragment RNA_lig_T4_1 PF09511.5 CDI85027.1 - 4 6.8 8.3 18 4.7 2.6 2.2 2 0 0 2 2 2 0 RNA ligase PIG-P PF08510.7 CDI85027.1 - 4.1 7.0 5.4 11 5.6 1.1 2.3 2 0 0 2 2 2 0 PIG-P DUF1943 PF09172.6 CDI85027.1 - 5.1 5.8 20.2 1 8.1 2.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1943) Folate_carrier PF01770.13 CDI85027.1 - 9.2 4.6 14.0 3.5 6.0 1.4 2.2 2 0 0 2 2 2 0 Reduced folate carrier DUF3332 PF11810.3 CDI85028.1 - 2.3 7.8 6.3 5.1 6.7 4.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3332) MAT1 PF06391.8 CDI85028.1 - 3.1 7.3 21.0 5.9 6.4 14.6 1.5 1 0 0 1 1 1 0 CDK-activating kinase assembly factor MAT1 Ribosomal_60s PF00428.14 CDI85029.1 - 0.019 15.3 8.1 0.034 14.5 5.6 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein ADP_PFK_GK PF04587.10 CDI85029.1 - 0.13 10.3 2.9 0.18 9.9 2.0 1.1 1 0 0 1 1 1 0 ADP-specific Phosphofructokinase/Glucokinase conserved region DUF572 PF04502.8 CDI85029.1 - 1.1 8.4 31.4 1.2 8.2 21.8 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF572) Utp14 PF04615.8 CDI85029.1 - 4.6 5.2 24.1 5.5 5.0 16.7 1.0 1 0 0 1 1 1 0 Utp14 protein MIP-T3 PF10243.4 CDI85029.1 - 6.1 5.1 31.5 7.5 4.8 21.8 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 SP2 PF03014.9 CDI85032.1 - 0.0032 15.4 2.5 0.0032 15.4 1.8 2.0 1 1 1 2 2 2 1 Structural protein 2 Pex14_N PF04695.8 CDI85032.1 - 0.0095 15.9 12.8 0.0095 15.9 8.8 2.0 1 1 1 2 2 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region PAP1 PF08601.5 CDI85032.1 - 0.14 11.8 8.7 0.14 11.8 6.0 1.0 1 0 0 1 1 1 0 Transcription factor PAP1 Herpes_gE PF02480.11 CDI85032.1 - 1.1 7.5 5.6 0.78 7.9 2.9 1.5 1 1 0 1 1 1 0 Alphaherpesvirus glycoprotein E Pex16 PF08610.5 CDI85032.1 - 1.1 8.2 6.5 1.4 7.8 4.5 1.2 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) DUF4653 PF15546.1 CDI85032.1 - 1.3 8.2 9.6 1.7 7.8 6.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4653) Pneumo_att_G PF05539.6 CDI85032.1 - 2.1 7.6 23.4 2.5 7.4 16.2 1.0 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G DUF4335 PF14233.1 CDI85032.1 - 2.2 7.7 10.7 1.9 7.8 4.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4335) Suf PF05843.9 CDI85032.1 - 4.9 6.7 7.8 5.9 6.5 5.4 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) RR_TM4-6 PF06459.7 CDI85032.1 - 5.3 6.8 6.3 6.5 6.5 4.4 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF1788 PF08747.6 CDI85034.1 - 0.025 14.4 7.3 0.028 14.2 5.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1788) Glyco_transf_15 PF01793.11 CDI85034.1 - 3.7 6.4 9.7 4.1 6.2 6.7 1.0 1 0 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase PP2C_2 PF13672.1 CDI85034.1 - 4.3 6.6 10.0 6.2 6.1 6.9 1.3 1 0 0 1 1 1 0 Protein phosphatase 2C Phi_1 PF04674.7 CDI85034.1 - 5.8 5.9 7.1 6.3 5.8 4.9 1.0 1 0 0 1 1 1 0 Phosphate-induced protein 1 conserved region Pex14_N PF04695.8 CDI85034.1 - 7 6.7 16.3 9.5 6.2 11.3 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF1764 PF08576.5 CDI85034.1 - 8.4 7.2 9.1 9.5 7.0 6.3 1.2 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) RNA_pol_Rpb1_5 PF04998.12 CDI85034.1 - 8.5 5.5 10.2 8.9 5.4 7.1 1.0 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 CAF-1_p150 PF11600.3 CDI85036.1 - 5.2 6.3 59.8 0.14 11.5 29.2 2.3 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Parvo_coat PF00740.13 CDI85036.1 - 8.5 5.1 38.5 12 4.7 26.7 1.2 1 0 0 1 1 1 0 Parvovirus coat protein VP2 Macoilin PF09726.4 CDI85037.1 - 0.32 9.2 67.1 0.42 8.8 46.5 1.1 1 0 0 1 1 1 0 Transmembrane protein DUF4175 PF13779.1 CDI85038.1 - 0.0049 14.6 11.7 0.0045 14.7 8.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4175) Tom22 PF04281.8 CDI85038.1 - 0.013 15.0 4.1 0.017 14.6 2.9 1.3 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 APC_CDC26 PF10471.4 CDI85038.1 - 0.019 15.6 19.5 0.037 14.7 13.5 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex APC subunit 1 DUF1635 PF07795.6 CDI85038.1 - 0.023 14.0 9.0 0.027 13.8 6.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) Med15 PF09606.5 CDI85038.1 - 0.026 12.7 19.6 0.03 12.5 13.6 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal FimP PF09766.4 CDI85038.1 - 0.032 13.3 13.2 0.036 13.1 9.2 1.1 1 0 0 1 1 1 0 Fms-interacting protein BROMI PF14961.1 CDI85038.1 - 0.032 11.3 0.9 0.03 11.4 0.6 1.0 1 0 0 1 1 1 0 Broad-minded protein Ctr PF04145.10 CDI85038.1 - 0.041 13.9 3.0 0.047 13.7 2.1 1.2 1 0 0 1 1 1 0 Ctr copper transporter family DUF2052 PF09747.4 CDI85038.1 - 0.041 13.8 9.5 0.041 13.7 6.6 1.1 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) Sporozoite_P67 PF05642.6 CDI85038.1 - 0.054 11.3 8.3 0.059 11.2 5.8 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF3276 PF11680.3 CDI85038.1 - 0.098 12.4 8.3 0.12 12.1 5.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3276) Trypan_glycop_C PF10659.4 CDI85038.1 - 0.1 12.9 5.3 0.16 12.3 3.6 1.3 1 0 0 1 1 1 0 Trypanosome variant surface glycoprotein C-terminal domain PhaC_N PF07167.8 CDI85038.1 - 0.1 12.0 2.6 0.12 11.8 1.8 1.2 1 0 0 1 1 1 0 Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus DUF4657 PF15552.1 CDI85038.1 - 0.11 11.8 13.4 0.13 11.5 9.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4657) Na_trans_assoc PF06512.8 CDI85038.1 - 0.13 12.1 5.0 0.15 12.0 3.5 1.1 1 0 0 1 1 1 0 Sodium ion transport-associated EPL1 PF10513.4 CDI85038.1 - 0.16 12.2 8.2 0.17 12.1 5.7 1.2 1 0 0 1 1 1 0 Enhancer of polycomb-like Asp-B-Hydro_N PF05279.6 CDI85038.1 - 0.16 11.7 6.5 0.17 11.7 4.5 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Plasmodium_Vir PF05795.6 CDI85038.1 - 0.17 11.0 4.7 0.18 10.9 3.2 1.0 1 0 0 1 1 1 0 Plasmodium vivax Vir protein RED_N PF07808.8 CDI85038.1 - 0.19 10.9 11.3 0.24 10.6 7.9 1.2 1 0 0 1 1 1 0 RED-like protein N-terminal region RP-C_C PF11800.3 CDI85038.1 - 0.23 11.1 8.1 0.27 10.9 5.6 1.2 1 0 0 1 1 1 0 Replication protein C C-terminal region Folliculin PF11704.3 CDI85038.1 - 0.23 11.0 5.3 0.31 10.5 3.7 1.2 1 0 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport TFIIF_alpha PF05793.7 CDI85038.1 - 0.29 9.4 9.8 0.41 8.9 6.8 1.3 1 1 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) BTV_NS2 PF04514.7 CDI85038.1 - 0.29 9.9 4.8 0.32 9.8 3.4 1.0 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Pex16 PF08610.5 CDI85038.1 - 0.31 9.9 6.9 0.35 9.8 4.8 1.1 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) FAM176 PF14851.1 CDI85038.1 - 0.33 10.6 3.6 0.37 10.4 2.5 1.1 1 0 0 1 1 1 0 FAM176 family FAM220 PF15487.1 CDI85038.1 - 0.38 10.0 10.5 0.43 9.9 7.3 1.0 1 0 0 1 1 1 0 FAM220 family Peptidase_S64 PF08192.6 CDI85038.1 - 0.39 8.9 9.1 0.43 8.8 6.3 1.0 1 0 0 1 1 1 0 Peptidase family S64 Hid1 PF12722.2 CDI85038.1 - 0.44 8.1 11.0 0.43 8.1 7.7 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF1764 PF08576.5 CDI85038.1 - 0.46 11.2 9.2 0.59 10.9 6.4 1.3 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) DUF4557 PF15101.1 CDI85038.1 - 0.48 10.2 13.6 0.53 10.0 9.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) FLO_LFY PF01698.11 CDI85038.1 - 0.49 9.1 7.0 0.52 9.1 4.8 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein F-protein PF00469.15 CDI85038.1 - 0.56 9.5 7.3 0.68 9.2 5.1 1.0 1 0 0 1 1 1 0 Negative factor, (F-Protein) or Nef DUF3464 PF11947.3 CDI85038.1 - 0.6 9.5 5.8 0.79 9.1 4.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) Neur_chan_memb PF02932.11 CDI85038.1 - 0.62 9.8 6.0 0.68 9.7 4.1 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF4045 PF13254.1 CDI85038.1 - 0.63 9.2 14.6 0.74 9.0 10.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) MRI PF15325.1 CDI85038.1 - 0.67 10.9 9.7 0.7 10.8 6.0 1.7 1 1 1 2 2 1 0 Modulator of retrovirus infection PRTP PF01366.13 CDI85038.1 - 0.74 7.7 8.8 0.81 7.6 6.1 1.1 1 0 0 1 1 1 0 Herpesvirus processing and transport protein POX PF07526.6 CDI85038.1 - 0.74 10.0 9.7 1 9.5 6.7 1.3 1 0 0 1 1 1 0 Associated with HOX NST1 PF13945.1 CDI85038.1 - 0.79 9.7 13.5 0.93 9.5 9.3 1.2 1 0 0 1 1 1 0 Salt tolerance down-regulator UPF0565 PF10561.4 CDI85038.1 - 0.8 8.5 7.7 0.83 8.4 5.4 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0565 Maf1 PF09174.5 CDI85038.1 - 0.8 9.5 7.4 0.87 9.4 5.1 1.1 1 0 0 1 1 1 0 Maf1 regulator DUF966 PF06136.8 CDI85038.1 - 0.87 8.9 11.8 1 8.7 8.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Rtf2 PF04641.7 CDI85038.1 - 0.95 8.6 9.4 1 8.5 6.5 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger DUF4220 PF13968.1 CDI85038.1 - 1 8.3 3.7 1 8.3 2.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4220) CPSF100_C PF13299.1 CDI85038.1 - 1 9.5 9.4 1.2 9.3 6.5 1.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Macoilin PF09726.4 CDI85038.1 - 1.1 7.4 10.5 1.2 7.3 7.3 1.1 1 0 0 1 1 1 0 Transmembrane protein FAM150 PF15129.1 CDI85038.1 - 1.2 9.0 4.5 1.5 8.7 3.2 1.2 1 0 0 1 1 1 0 FAM150 family DUF4611 PF15387.1 CDI85038.1 - 1.2 9.3 9.6 2.3 8.4 6.7 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4611) Gti1_Pac2 PF09729.4 CDI85038.1 - 1.4 8.7 6.6 1.6 8.5 4.6 1.1 1 0 0 1 1 1 0 Gti1/Pac2 family DUF2572 PF10833.3 CDI85038.1 - 1.4 8.2 7.1 1.5 8.1 4.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2572) Band_3_cyto PF07565.8 CDI85038.1 - 1.4 8.3 8.3 1.6 8.1 5.7 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain ATAD4 PF15321.1 CDI85038.1 - 2 9.4 7.9 3.3 8.7 5.5 1.5 1 0 0 1 1 1 0 ATPase family AAA domain containing 4 DUF2217 PF10265.4 CDI85038.1 - 2.2 6.9 8.7 2.3 6.8 6.0 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) FAM60A PF15396.1 CDI85038.1 - 2.2 7.9 7.5 2.4 7.8 5.2 1.1 1 0 0 1 1 1 0 Protein Family FAM60A Glyco_transf_15 PF01793.11 CDI85038.1 - 2.3 7.0 6.9 2.5 6.9 4.8 1.1 1 0 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase Bap31 PF05529.7 CDI85038.1 - 2.3 7.6 8.8 2.8 7.3 6.1 1.1 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like Ycf1 PF05758.7 CDI85038.1 - 2.4 5.7 9.1 2.5 5.7 6.3 1.0 1 0 0 1 1 1 0 Ycf1 DUF3533 PF12051.3 CDI85038.1 - 2.4 6.7 7.2 2.5 6.7 5.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3533) OATP PF03137.15 CDI85038.1 - 2.5 6.0 4.3 2.9 5.8 3.0 1.2 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Mucin PF01456.12 CDI85038.1 - 3 7.5 13.8 3.7 7.3 9.6 1.1 1 0 0 1 1 1 0 Mucin-like glycoprotein DDHD PF02862.12 CDI85038.1 - 3.1 7.5 9.1 3.3 7.4 6.3 1.1 1 0 0 1 1 1 0 DDHD domain DUF3449 PF11931.3 CDI85038.1 - 3.1 7.2 11.3 3.8 6.9 7.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3449) Tim54 PF11711.3 CDI85038.1 - 3.3 6.2 8.6 3.4 6.1 6.0 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DUF853 PF05872.7 CDI85038.1 - 4.5 5.4 9.0 5.1 5.3 6.2 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) Folate_carrier PF01770.13 CDI85038.1 - 4.7 5.6 5.2 5.3 5.4 3.6 1.1 1 0 0 1 1 1 0 Reduced folate carrier DUF3994 PF13159.1 CDI85038.1 - 5 7.4 8.9 6.1 7.1 6.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3994) Lin-8 PF03353.10 CDI85038.1 - 5.5 6.1 13.4 6.2 6.0 9.3 1.0 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Paramyxo_ncap PF00973.14 CDI85038.1 - 5.6 5.5 7.7 5.9 5.4 5.3 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Mem_trans PF03547.13 CDI85038.1 - 5.8 5.0 6.6 6.6 4.9 4.6 1.1 1 0 0 1 1 1 0 Membrane transport protein Ndc1_Nup PF09531.5 CDI85038.1 - 6.2 5.1 12.3 6.8 4.9 8.6 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Presenilin PF01080.12 CDI85038.1 - 9.2 4.9 8.2 9.7 4.8 5.7 1.1 1 0 0 1 1 1 0 Presenilin Cornifin PF02389.10 CDI85040.1 - 1.7e-05 24.7 7.1 0.017 14.8 0.5 2.9 1 1 2 3 3 3 3 Cornifin (SPRR) family NSP13 PF06460.7 CDI85040.1 - 0.0046 15.8 12.4 6.7 5.4 0.1 4.6 1 1 3 4 4 4 4 Coronavirus NSP13 Gp5_C PF06715.7 CDI85040.1 - 0.83 9.7 45.9 4 7.5 0.1 10.6 3 3 9 14 14 14 0 Gp5 C-terminal repeat (3 copies) Chordopox_G3 PF06129.7 CDI85040.1 - 8.8 6.5 21.0 20 5.3 0.9 4.2 1 1 3 4 4 4 0 Chordopoxvirus G3 protein SR-25 PF10500.4 CDI85041.1 - 0.02 14.3 26.3 0.027 13.9 18.2 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein CAF-1_p150 PF11600.3 CDI85041.1 - 0.58 9.5 38.7 0.72 9.1 26.8 1.0 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal RR_TM4-6 PF06459.7 CDI85041.1 - 1 9.2 27.2 1.2 8.9 18.9 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 eIF3_subunit PF08597.5 CDI85041.1 - 1.5 8.3 24.9 1.8 8.0 17.3 1.1 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit DDRGK PF09756.4 CDI85041.1 - 1.6 8.0 34.9 2 7.8 24.2 1.2 1 0 0 1 1 1 0 DDRGK domain SprA-related PF12118.3 CDI85041.1 - 2.5 7.3 63.5 3.1 7.0 44.0 1.1 1 0 0 1 1 1 0 SprA-related family FLO_LFY PF01698.11 CDI85041.1 - 3.8 6.2 31.0 4.1 6.1 21.5 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein NARP1 PF12569.3 CDI85041.1 - 5.4 5.6 27.3 6.4 5.4 18.9 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Tim54 PF11711.3 CDI85041.1 - 8.6 4.8 19.6 12 4.3 13.6 1.4 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DUF2126 PF09899.4 CDI85041.1 - 9.4 4.1 18.4 9.9 4.0 12.8 1.2 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) Med15 PF09606.5 CDI85042.1 - 0.39 8.8 84.8 0.51 8.4 58.8 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Daxx PF03344.10 CDI85043.1 - 0.00024 19.7 30.1 0.00029 19.5 20.9 1.0 1 0 0 1 1 1 1 Daxx Family TFIIF_alpha PF05793.7 CDI85043.1 - 0.0045 15.4 27.8 0.0054 15.1 19.3 1.1 1 0 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Utp14 PF04615.8 CDI85043.1 - 0.097 10.8 18.3 0.12 10.5 12.7 1.0 1 0 0 1 1 1 0 Utp14 protein Paf1 PF03985.8 CDI85043.1 - 0.12 11.0 25.9 0.17 10.5 18.0 1.4 1 0 0 1 1 1 0 Paf1 DUF2457 PF10446.4 CDI85043.1 - 0.15 10.7 27.7 0.19 10.4 19.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Nop14 PF04147.7 CDI85043.1 - 1.2 6.9 29.5 1.5 6.6 20.4 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 CDI85043.1 - 1.5 6.8 19.9 2 6.3 13.8 1.3 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.7 CDI85043.1 - 2.5 7.3 29.5 3.2 6.9 20.4 1.1 1 0 0 1 1 1 0 SDA1 Ycf1 PF05758.7 CDI85043.1 - 2.6 5.6 13.5 2.9 5.4 9.3 1.0 1 0 0 1 1 1 0 Ycf1 BUD22 PF09073.5 CDI85043.1 - 4 6.4 34.0 5.5 5.9 23.6 1.2 1 0 0 1 1 1 0 BUD22 UPF0564 PF10595.4 CDI85043.1 - 4.4 6.1 16.4 7.6 5.3 11.4 1.3 1 0 0 1 1 1 0 Uncharacterised protein family UPF0564 Lin-8 PF03353.10 CDI85043.1 - 6 6.0 15.2 7.4 5.7 10.5 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Peptidase_S64 PF08192.6 CDI85043.1 - 7.9 4.6 10.2 9.2 4.4 7.0 1.1 1 0 0 1 1 1 0 Peptidase family S64 Rifin_STEVOR PF02009.11 CDI85045.1 - 0.043 13.4 6.0 0.061 12.9 4.2 1.2 1 0 0 1 1 1 0 Rifin/stevor family Ribosomal_60s PF00428.14 CDI85045.1 - 0.09 13.1 6.6 0.14 12.5 4.5 1.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein PsbQ PF05757.6 CDI85045.1 - 0.24 10.8 5.1 0.34 10.3 3.6 1.2 1 0 0 1 1 1 0 Oxygen evolving enhancer protein 3 (PsbQ) TFIIA PF03153.8 CDI85045.1 - 0.32 10.8 10.6 0.35 10.6 7.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF3357 PF11837.3 CDI85045.1 - 0.4 10.5 8.1 1.3 8.9 2.3 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3357) PepSY_2 PF13670.1 CDI85045.1 - 1.3 8.9 6.9 19 5.2 6.2 1.9 2 0 0 2 2 2 0 Peptidase propeptide and YPEB domain Plant_vir_prot PF01307.12 CDI85045.1 - 1.6 8.4 5.4 1.1 9.0 2.1 1.8 1 1 1 2 2 2 0 Plant viral movement protein DUF3753 PF12575.3 CDI85045.1 - 2 8.2 4.5 1.5 8.6 2.0 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3753) TMEM154 PF15102.1 CDI85045.1 - 5.2 6.7 11.6 1.2 8.8 5.8 1.6 1 1 1 2 2 2 0 TMEM154 protein family MSP1_C PF07462.6 CDI85045.1 - 5.9 5.1 7.7 5.8 5.1 5.3 1.1 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus DUF912 PF06024.7 CDI85045.1 - 8.6 6.4 6.6 3.4 7.7 2.4 2.0 1 1 1 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF755 PF05501.6 CDI85047.1 - 0.0094 16.0 28.7 0.0094 16.0 19.9 4.3 3 1 1 4 4 4 2 Domain of unknown function (DUF755) FCP1_C PF09309.5 CDI85047.1 - 0.011 15.0 12.4 0.011 15.0 8.6 3.2 2 1 1 3 3 3 0 FCP1, C-terminal zf-CCCH PF00642.19 CDI85049.1 - 0.01 15.5 4.1 0.023 14.3 2.8 1.6 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_1 PF00076.17 CDI85050.1 - 2e-18 65.7 0.0 3.6e-18 64.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CDI85050.1 - 9.4e-14 51.1 0.0 1.7e-13 50.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CDI85050.1 - 5.7e-10 38.9 0.0 9.9e-10 38.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SR-25 PF10500.4 CDI85050.1 - 0.00012 21.6 39.9 0.0015 18.0 10.9 3.1 3 0 0 3 3 3 3 Nuclear RNA-splicing-associated protein CDK2AP PF09806.4 CDI85050.1 - 0.00022 21.5 18.7 0.00022 21.5 13.0 3.4 2 1 1 3 3 2 1 Cyclin-dependent kinase 2-associated protein BAF1_ABF1 PF04684.8 CDI85050.1 - 0.00074 18.4 8.7 0.00074 18.4 6.0 3.8 3 1 1 4 4 2 1 BAF1 / ABF1 chromatin reorganising factor GET2 PF08690.5 CDI85050.1 - 0.16 11.1 12.1 0.025 13.8 4.0 2.1 2 0 0 2 2 2 0 GET complex subunit GET2 Ycf1 PF05758.7 CDI85050.1 - 0.63 7.6 14.0 0.13 9.9 5.1 2.0 2 0 0 2 2 2 0 Ycf1 DUF4647 PF15504.1 CDI85050.1 - 3.3 6.4 27.1 1.2 7.9 11.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4647) Ndc1_Nup PF09531.5 CDI85050.1 - 3.4 5.9 28.5 0.33 9.3 9.0 2.2 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup SAPS PF04499.10 CDI85050.1 - 7.6 5.0 19.0 3.3 6.2 7.4 2.1 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein DUF1777 PF08648.7 CDI85050.1 - 8 6.1 33.2 4.3 7.0 5.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1777) TraT PF05818.7 CDI85051.1 - 0.0052 16.2 7.0 0.0052 16.2 4.9 5.5 3 2 1 4 4 4 1 Enterobacterial TraT complement resistance protein DTW PF03942.10 CDI85053.1 - 0.028 13.6 0.2 0.028 13.6 0.1 1.1 1 0 0 1 1 1 0 DTW domain SET_assoc PF11767.3 CDI85053.1 - 0.04 13.2 0.0 0.044 13.0 0.0 1.1 1 0 0 1 1 1 0 Histone lysine methyltransferase SET associated DUF4512 PF14975.1 CDI85053.1 - 0.056 14.2 0.2 0.069 13.9 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4512) Peptidase_C12 PF01088.16 CDI85053.1 - 0.056 12.6 2.3 0.064 12.4 1.6 1.1 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase, family 1 Codanin-1_C PF15296.1 CDI85053.1 - 0.19 11.6 6.7 0.23 11.3 4.6 1.1 1 0 0 1 1 1 0 Codanin-1 C-terminus Spt20 PF12090.3 CDI85053.1 - 0.67 9.2 6.6 0.74 9.1 4.6 1.2 1 0 0 1 1 1 0 Spt20 family MRI PF15325.1 CDI85054.1 - 0.021 15.8 12.7 0.021 15.8 8.8 4.0 2 1 1 3 3 3 0 Modulator of retrovirus infection SDA1 PF05285.7 CDI85054.1 - 0.34 10.1 59.6 0.34 10.1 29.9 2.4 2 0 0 2 2 2 0 SDA1 Utp14 PF04615.8 CDI85054.1 - 2 6.4 58.6 2.6 6.1 40.6 1.1 1 0 0 1 1 1 0 Utp14 protein SprA-related PF12118.3 CDI85055.1 - 0.0011 18.3 64.3 0.0011 18.3 44.6 2.1 2 0 0 2 2 2 1 SprA-related family CDC27 PF09507.5 CDI85055.1 - 0.013 14.7 41.5 0.017 14.3 28.7 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 SOBP PF15279.1 CDI85055.1 - 0.013 15.8 35.1 0.018 15.4 24.3 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein AAA_23 PF13476.1 CDI85055.1 - 0.024 14.9 25.9 0.034 14.4 17.9 1.2 1 0 0 1 1 1 0 AAA domain eIF-3_zeta PF05091.7 CDI85055.1 - 0.16 10.5 26.0 0.22 10.1 18.0 1.4 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) UPF0564 PF10595.4 CDI85055.1 - 0.29 9.9 42.3 0.42 9.4 29.3 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0564 Med19 PF10278.4 CDI85055.1 - 0.33 10.6 16.7 0.54 9.9 11.6 1.4 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 DUF3337 PF11816.3 CDI85055.1 - 0.85 8.9 29.9 1.1 8.5 20.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3337) DUF605 PF04652.11 CDI85055.1 - 0.93 8.8 47.2 1.3 8.3 32.8 1.1 1 0 0 1 1 1 0 Vta1 like CAF-1_p150 PF11600.3 CDI85055.1 - 1.2 8.4 57.5 4.4 6.6 39.8 1.8 1 1 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal BTV_NS2 PF04514.7 CDI85055.1 - 3.6 6.3 21.8 5.7 5.7 15.1 1.4 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 PAT1 PF09770.4 CDI85055.1 - 5.5 5.0 63.6 7.5 4.6 44.1 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 GAGA_bind PF06217.7 CDI85055.1 - 5.6 6.8 31.9 7.5 6.4 22.1 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family Sec62 PF03839.11 CDI85055.1 - 6 6.2 19.5 8.8 5.6 13.5 1.4 1 0 0 1 1 1 0 Translocation protein Sec62 APG6 PF04111.7 CDI85055.1 - 8.5 5.3 32.1 11 4.9 22.2 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF747 PF05346.6 CDI85056.1 - 4e-27 95.1 0.0 4e-27 95.1 0.0 3.0 3 0 0 3 3 3 1 Eukaryotic membrane protein family Med15 PF09606.5 CDI85056.1 - 8.8e-06 24.2 142.6 8.8e-06 24.2 98.9 10.7 3 1 5 10 10 10 2 ARC105 or Med15 subunit of Mediator complex non-fungal SOBP PF15279.1 CDI85056.1 - 5.4e-05 23.7 18.2 5.4e-05 23.7 12.6 9.8 4 3 4 8 8 8 1 Sine oculis-binding protein RVT_1 PF00078.22 CDI85059.1 - 2.6e-10 40.0 0.0 4.6e-10 39.2 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Helicase_C PF00271.26 CDI85060.1 - 4.5e-13 48.8 0.1 7e-12 45.0 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Activator_LAG-3 PF11498.3 CDI85061.1 - 0.043 12.5 37.5 0.0074 15.0 19.2 2.2 2 0 0 2 2 2 0 Transcriptional activator LAG-3 Peptidase_S49_N PF08496.5 CDI85061.1 - 0.27 10.9 5.4 0.53 10.0 3.7 1.6 1 0 0 1 1 1 0 Peptidase family S49 N-terminal CAF-1_p150 PF11600.3 CDI85061.1 - 0.43 9.9 24.8 0.028 13.8 6.8 2.2 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Zip PF02535.17 CDI85061.1 - 0.93 8.4 7.5 0.67 8.8 1.0 2.1 2 0 0 2 2 2 0 ZIP Zinc transporter vMSA PF00695.14 CDI85061.1 - 2.7 7.0 8.6 4 6.5 5.9 1.4 1 0 0 1 1 1 0 Major surface antigen from hepadnavirus PAT1 PF09770.4 CDI85061.1 - 2.8 6.0 48.0 4 5.5 33.3 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Suf PF05843.9 CDI85062.1 - 0.19 11.4 4.6 0.38 10.4 3.2 1.5 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) CDK5_activator PF03261.10 CDI85062.1 - 0.87 8.8 6.0 1.6 7.9 4.1 1.4 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein DUF1427 PF07235.6 CDI85062.1 - 5.8 7.0 7.3 40 4.3 0.1 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1427) COPI_assoc PF08507.5 CDI85064.1 - 2.6e-10 40.1 1.4 3.5e-10 39.6 1.0 1.2 1 0 0 1 1 1 1 COPI associated protein Neurensin PF14927.1 CDI85064.1 - 0.0092 15.3 0.0 0.0092 15.3 0.0 1.9 2 1 0 2 2 2 1 Neurensin G-patch PF01585.18 CDI85066.1 - 5.8e-14 51.5 1.0 1.3e-13 50.4 0.7 1.6 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 CDI85066.1 - 0.0004 20.1 0.5 0.0016 18.2 0.3 2.0 1 0 0 1 1 1 1 DExH-box splicing factor binding site RRM_1 PF00076.17 CDI85066.1 - 0.008 15.7 0.0 0.016 14.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CDI85066.1 - 0.018 14.8 0.0 0.034 13.9 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AAA_12 PF13087.1 CDI85067.1 - 2.1e-52 177.4 0.0 3.7e-52 176.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 CDI85067.1 - 2e-46 158.5 1.2 3.4e-46 157.7 0.0 2.0 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.1 CDI85067.1 - 1.3e-13 50.4 0.3 5.9e-13 48.3 0.0 2.2 3 0 0 3 3 2 1 Part of AAA domain AAA_30 PF13604.1 CDI85067.1 - 1.4e-10 41.0 0.0 2.8e-09 36.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain PIF1 PF05970.9 CDI85067.1 - 5.4e-05 22.3 0.0 0.0052 15.7 0.0 2.2 2 0 0 2 2 2 1 PIF1-like helicase dsrm PF00035.20 CDI85067.1 - 0.00034 21.1 0.7 0.099 13.2 0.0 2.9 2 0 0 2 2 2 1 Double-stranded RNA binding motif DUF2075 PF09848.4 CDI85067.1 - 0.00037 19.5 0.2 0.027 13.4 0.0 2.5 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) NACHT PF05729.7 CDI85067.1 - 0.0011 18.6 0.0 0.0029 17.3 0.0 1.7 1 0 0 1 1 1 1 NACHT domain PhoH PF02562.11 CDI85067.1 - 0.0011 18.2 0.0 0.004 16.3 0.0 1.8 2 0 0 2 2 2 1 PhoH-like protein IstB_IS21 PF01695.12 CDI85067.1 - 0.0021 17.5 0.0 0.0053 16.1 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein Viral_helicase1 PF01443.13 CDI85067.1 - 0.011 15.2 0.0 1.4 8.4 0.0 3.1 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase ResIII PF04851.10 CDI85067.1 - 0.011 15.5 0.1 0.051 13.3 0.0 2.0 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit DEAD PF00270.24 CDI85067.1 - 0.012 15.1 0.1 0.097 12.1 0.0 2.3 2 0 0 2 2 2 0 DEAD/DEAH box helicase AAA PF00004.24 CDI85067.1 - 0.02 15.1 0.0 0.066 13.4 0.0 1.9 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) UvrD-helicase PF00580.16 CDI85067.1 - 0.033 13.5 0.6 0.1 11.8 0.0 1.9 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain Mg_chelatase PF01078.16 CDI85067.1 - 0.069 12.3 0.1 0.21 10.7 0.0 1.8 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 CDI85067.1 - 0.074 12.5 0.0 0.19 11.2 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_25 PF13481.1 CDI85067.1 - 0.094 12.1 0.0 0.21 10.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 CDI85067.1 - 0.14 12.3 0.0 0.42 10.7 0.0 1.9 1 0 0 1 1 1 0 AAA domain DSPc PF00782.15 CDI85068.1 - 4.2e-23 81.4 0.0 3.6e-18 65.4 0.1 2.7 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 CDI85068.1 - 0.0012 18.2 0.0 0.0022 17.3 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase eIF3_p135 PF12807.2 CDI85070.1 - 0.00016 21.6 0.0 0.0004 20.3 0.0 1.6 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit 135 MORN PF02493.15 CDI85071.1 - 4.4e-27 92.1 50.0 0.0001 21.7 0.4 10.8 10 0 0 10 10 10 8 MORN repeat Avl9 PF09794.4 CDI85071.1 - 7e-15 54.3 0.0 7.3e-13 47.7 0.0 2.2 1 1 1 2 2 2 2 Transport protein Avl9 DENN PF02141.16 CDI85071.1 - 0.0018 18.0 0.3 0.0034 17.1 0.2 1.3 1 0 0 1 1 1 1 DENN (AEX-3) domain SPA PF08616.5 CDI85071.1 - 0.099 12.3 0.1 0.2 11.3 0.1 1.4 1 0 0 1 1 1 0 Stabilization of polarity axis DUF2347 PF09804.4 CDI85071.1 - 0.33 10.1 0.1 0.69 9.1 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2347) RAMP4 PF06624.7 CDI85072.1 - 1.1e-23 82.5 0.4 1.4e-23 82.1 0.3 1.2 1 0 0 1 1 1 1 Ribosome associated membrane protein RAMP4 PMP1_2 PF08114.6 CDI85072.1 - 0.19 11.2 0.6 0.3 10.5 0.4 1.3 1 0 0 1 1 1 0 ATPase proteolipid family Choline_transpo PF04515.7 CDI85073.1 - 5e-25 87.9 27.2 6.6e-24 84.2 2.6 3.5 3 1 1 4 4 4 3 Plasma-membrane choline transporter MCM_N PF14551.1 CDI85074.1 - 0.0081 16.6 0.0 0.029 14.8 0.0 1.9 1 1 0 1 1 1 1 MCM N-terminal domain Gryzun PF07919.7 CDI85074.1 - 0.064 11.5 4.4 0.084 11.1 3.1 1.1 1 0 0 1 1 1 0 Gryzun, putative trafficking through Golgi Suf PF05843.9 CDI85074.1 - 0.098 12.3 5.8 0.15 11.7 3.6 1.6 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) Pex14_N PF04695.8 CDI85074.1 - 0.15 12.1 6.7 0.4 10.7 4.7 1.8 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region G0-G1_switch_2 PF15103.1 CDI85074.1 - 0.73 10.0 5.7 0.28 11.4 1.6 2.0 2 0 0 2 2 2 0 G0/G1 switch protein 2 Activator_LAG-3 PF11498.3 CDI85074.1 - 0.81 8.3 32.1 1.5 7.5 22.3 1.3 1 0 0 1 1 1 0 Transcriptional activator LAG-3 PSCyt3 PF07627.6 CDI85074.1 - 0.91 9.4 7.7 0.68 9.8 2.2 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1588) DUF4557 PF15101.1 CDI85074.1 - 2.9 7.7 14.4 0.088 12.6 5.3 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4557) Med15 PF09606.5 CDI85075.1 - 2.3 6.2 55.2 4.3 5.4 38.3 1.4 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Ketoacyl-synt_C PF02801.17 CDI85076.1 - 3.1e-15 56.0 5.5 5.1e-12 45.6 0.4 6.5 6 1 0 6 6 6 2 Beta-ketoacyl synthase, C-terminal domain PAT1 PF09770.4 CDI85076.1 - 0.00054 18.3 31.5 0.00054 18.3 21.8 7.0 6 2 0 6 6 6 1 Topoisomerase II-associated protein PAT1 CAF-1_p150 PF11600.3 CDI85076.1 - 0.0016 17.8 14.1 0.0016 17.8 9.7 13.7 12 2 1 13 13 13 2 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF562 PF04763.7 CDI85078.1 - 0.042 13.0 0.4 0.042 13.0 0.3 1.9 3 0 0 3 3 3 0 Protein of unknown function (DUF562) Herpes_DNAp_acc PF04929.7 CDI85078.1 - 0.31 9.9 26.3 0.35 9.7 18.2 1.0 1 0 0 1 1 1 0 Herpes DNA replication accessory factor FAM60A PF15396.1 CDI85078.1 - 9.4 5.9 19.5 11 5.6 13.5 1.2 1 0 0 1 1 1 0 Protein Family FAM60A DUF1510 PF07423.6 CDI85079.1 - 0.003 16.9 17.1 0.0094 15.3 5.7 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1510) Suf PF05843.9 CDI85079.1 - 0.0049 16.6 24.0 0.036 13.7 4.0 2.2 2 0 0 2 2 2 2 Suppressor of forked protein (Suf) Spt20 PF12090.3 CDI85079.1 - 0.0049 16.2 1.2 0.0049 16.2 0.8 2.5 2 1 0 2 2 1 1 Spt20 family PPP4R2 PF09184.6 CDI85079.1 - 0.011 15.3 4.3 0.011 15.3 3.0 2.1 2 0 0 2 2 2 0 PPP4R2 FimP PF09766.4 CDI85079.1 - 0.026 13.6 33.1 0.31 10.0 5.6 2.1 2 0 0 2 2 2 0 Fms-interacting protein PAT1 PF09770.4 CDI85079.1 - 0.031 12.5 38.6 0.13 10.4 11.0 2.1 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 DDHD PF02862.12 CDI85079.1 - 0.042 13.6 16.2 0.6 9.8 7.3 2.1 2 0 0 2 2 2 0 DDHD domain YfhO PF09586.5 CDI85079.1 - 0.088 10.8 4.4 1.1 7.1 0.2 2.0 2 0 0 2 2 2 0 Bacterial membrane protein YfhO Zip PF02535.17 CDI85079.1 - 0.091 11.7 1.4 0.57 9.1 0.9 2.0 2 0 0 2 2 2 0 ZIP Zinc transporter Gag_spuma PF03276.9 CDI85079.1 - 0.13 10.5 35.0 0.38 9.0 5.9 2.2 2 0 0 2 2 2 0 Spumavirus gag protein Neur_chan_memb PF02932.11 CDI85079.1 - 0.16 11.7 8.7 4.4 7.1 3.6 2.1 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region BNIP3 PF06553.7 CDI85079.1 - 0.66 9.3 19.2 1.5 8.1 9.2 2.1 2 0 0 2 2 2 0 BNIP3 DUF913 PF06025.7 CDI85079.1 - 1.1 7.9 9.3 3 6.5 3.0 2.2 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) SPX PF03105.14 CDI85079.1 - 1.2 8.8 16.8 3.3 7.4 0.2 2.1 2 0 0 2 2 2 0 SPX domain AUX_IAA PF02309.11 CDI85079.1 - 1.3 8.7 14.5 7.1 6.3 0.1 2.2 2 0 0 2 2 2 0 AUX/IAA family Serinc PF03348.10 CDI85079.1 - 1.4 7.5 18.2 1 8.0 5.3 2.1 2 0 0 2 2 2 0 Serine incorporator (Serinc) Band_3_cyto PF07565.8 CDI85079.1 - 1.8 8.0 20.8 0.97 8.8 0.3 2.1 2 0 0 2 2 2 0 Band 3 cytoplasmic domain Zn_peptidase PF04228.8 CDI85079.1 - 2 7.5 17.7 0.03 13.5 2.0 2.4 2 0 0 2 2 2 0 Putative neutral zinc metallopeptidase Rtf2 PF04641.7 CDI85079.1 - 2.1 7.5 18.5 2.6 7.1 0.2 2.1 2 0 0 2 2 2 0 Rtf2 RING-finger SR-25 PF10500.4 CDI85079.1 - 2.7 7.3 29.4 0.52 9.7 13.2 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein DUF4557 PF15101.1 CDI85079.1 - 2.9 7.6 31.9 4.5 7.0 9.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4557) BPD_transp_2 PF02653.11 CDI85079.1 - 2.9 6.7 7.4 0.39 9.6 0.1 2.6 2 1 0 2 2 2 0 Branched-chain amino acid transport system / permease component Gti1_Pac2 PF09729.4 CDI85079.1 - 3.9 7.3 13.6 3.9 7.3 0.0 2.2 2 0 0 2 2 2 0 Gti1/Pac2 family Dala_Dala_lig_N PF01820.16 CDI85079.1 - 5.3 7.3 9.8 15 5.8 0.1 2.4 2 0 0 2 2 2 0 D-ala D-ala ligase N-terminus CPSF100_C PF13299.1 CDI85079.1 - 5.8 7.0 15.3 9.2 6.4 0.3 2.2 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal MRP-S26 PF14943.1 CDI85079.1 - 6.2 6.3 25.4 1.6 8.2 7.6 2.2 2 0 0 2 2 2 0 Mitochondrial ribosome subunit S26 Baculo_PP31 PF05311.6 CDI85079.1 - 6.8 5.8 17.6 0.55 9.4 3.9 2.1 2 0 0 2 2 2 0 Baculovirus 33KDa late protein (PP31) Ycf1 PF05758.7 CDI85079.1 - 7.5 4.1 16.9 2.8 5.5 5.9 2.0 2 0 0 2 2 2 0 Ycf1 Peptidase_S49_N PF08496.5 CDI85079.1 - 8.2 6.2 15.9 5.9 6.6 3.5 2.3 2 0 0 2 2 2 0 Peptidase family S49 N-terminal MRP-S31 PF15433.1 CDI85079.1 - 8.2 5.7 25.6 1.6 8.0 1.1 2.3 2 0 0 2 2 2 0 Mitochondrial 28S ribosomal protein S31 OATP PF03137.15 CDI85079.1 - 9.9 4.0 13.3 0.85 7.5 0.1 2.1 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family GvpL_GvpF PF06386.6 CDI85080.1 - 0.0057 16.2 11.9 0.0059 16.2 8.2 1.0 1 0 0 1 1 1 1 Gas vesicle synthesis protein GvpL/GvpF IF-2B PF01008.12 CDI85080.1 - 0.037 13.0 4.1 0.04 12.9 2.8 1.0 1 0 0 1 1 1 0 Initiation factor 2 subunit family FPN1 PF06963.7 CDI85080.1 - 0.048 12.0 6.9 0.053 11.9 4.8 1.0 1 0 0 1 1 1 0 Ferroportin1 (FPN1) Phage_int_SAM_5 PF13102.1 CDI85080.1 - 0.059 13.3 10.2 0.071 13.1 7.1 1.0 1 0 0 1 1 1 0 Phage integrase SAM-like domain DUF3029 PF11230.3 CDI85080.1 - 0.11 10.6 3.6 0.12 10.5 2.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3029) MotA_ExbB PF01618.11 CDI85080.1 - 0.14 11.7 6.4 0.16 11.5 4.4 1.1 1 0 0 1 1 1 0 MotA/TolQ/ExbB proton channel family PP2C_2 PF13672.1 CDI85080.1 - 0.16 11.3 8.8 0.18 11.1 6.1 1.0 1 0 0 1 1 1 0 Protein phosphatase 2C Ufd2P_core PF10408.4 CDI85080.1 - 0.19 9.9 16.5 0.23 9.6 11.4 1.0 1 0 0 1 1 1 0 Ubiquitin elongating factor core SART-1 PF03343.8 CDI85080.1 - 0.36 9.1 8.4 0.38 9.0 5.8 1.0 1 0 0 1 1 1 0 SART-1 family DUF912 PF06024.7 CDI85080.1 - 0.37 10.8 4.3 0.46 10.5 3.0 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) YkuI_C PF10388.4 CDI85080.1 - 0.37 10.4 10.3 0.39 10.3 7.1 1.1 1 0 0 1 1 1 0 EAL-domain associated signalling protein domain PP_kinase_N PF13089.1 CDI85080.1 - 0.39 10.8 11.4 0.47 10.5 7.9 1.1 1 0 0 1 1 1 0 Polyphosphate kinase N-terminal domain Herpes_TK PF00693.13 CDI85080.1 - 0.51 9.4 3.8 0.55 9.3 2.6 1.0 1 0 0 1 1 1 0 Thymidine kinase from herpesvirus PEPcase_2 PF14010.1 CDI85080.1 - 0.53 8.5 4.5 0.52 8.5 3.1 1.0 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxylase RabGAP-TBC PF00566.13 CDI85080.1 - 0.78 9.1 12.9 0.83 9.0 8.9 1.0 1 0 0 1 1 1 0 Rab-GTPase-TBC domain Ribosomal_L6e PF01159.14 CDI85080.1 - 0.88 9.8 7.3 0.93 9.7 5.1 1.1 1 0 0 1 1 1 0 Ribosomal protein L6e Gti1_Pac2 PF09729.4 CDI85080.1 - 0.89 9.4 4.6 0.96 9.2 3.2 1.0 1 0 0 1 1 1 0 Gti1/Pac2 family Peptidase_U57 PF05582.7 CDI85080.1 - 1 8.2 8.9 1.1 8.1 6.1 1.0 1 0 0 1 1 1 0 YabG peptidase U57 RED_N PF07808.8 CDI85080.1 - 1.2 8.2 16.2 1.4 8.1 11.2 1.1 1 0 0 1 1 1 0 RED-like protein N-terminal region DUF3492 PF11997.3 CDI85080.1 - 1.3 8.5 5.8 1.3 8.4 4.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3492) Glyco_transf_15 PF01793.11 CDI85080.1 - 1.3 7.9 7.6 1.4 7.8 5.3 1.0 1 0 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase ThylakoidFormat PF11264.3 CDI85080.1 - 1.4 8.4 11.5 1.5 8.4 8.0 1.0 1 0 0 1 1 1 0 Thylakoid formation protein Anoctamin PF04547.7 CDI85080.1 - 1.5 7.3 6.9 1.7 7.2 4.8 1.0 1 0 0 1 1 1 0 Calcium-activated chloride channel Pex14_N PF04695.8 CDI85080.1 - 1.7 8.6 14.5 2 8.4 10.1 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Conotoxin PF02950.12 CDI85080.1 - 1.8 9.4 7.2 2.1 9.1 5.0 1.2 1 0 0 1 1 1 0 Conotoxin CemA PF03040.9 CDI85080.1 - 2.1 7.9 6.9 2 7.9 4.8 1.0 1 0 0 1 1 1 0 CemA family DUF342 PF03961.8 CDI85080.1 - 2.7 6.3 11.1 2.6 6.3 7.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) BsuBI_PstI_RE PF06616.6 CDI85080.1 - 2.8 6.6 7.9 2.9 6.6 5.4 1.0 1 0 0 1 1 1 0 BsuBI/PstI restriction endonuclease C-terminus Bud13 PF09736.4 CDI85080.1 - 2.9 8.1 12.6 3.3 7.9 8.7 1.1 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex Neur_chan_memb PF02932.11 CDI85080.1 - 3 7.6 4.7 3.4 7.4 3.3 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF2813 PF11398.3 CDI85080.1 - 3 6.8 14.1 3.1 6.8 9.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2813) eIF3_subunit PF08597.5 CDI85080.1 - 3.3 7.2 9.8 3.8 7.0 6.8 1.0 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit Peptidase_M9 PF01752.12 CDI85080.1 - 3.3 6.5 11.3 3.4 6.5 7.8 1.0 1 0 0 1 1 1 0 Collagenase Glt_symporter PF03616.9 CDI85080.1 - 3.5 6.0 5.5 3.9 5.8 3.8 1.1 1 0 0 1 1 1 0 Sodium/glutamate symporter ATAD4 PF15321.1 CDI85080.1 - 3.6 8.6 5.8 4.7 8.2 4.0 1.2 1 0 0 1 1 1 0 ATPase family AAA domain containing 4 YjgP_YjgQ PF03739.9 CDI85080.1 - 4.2 6.0 5.4 5 5.7 3.7 1.0 1 0 0 1 1 1 0 Predicted permease YjgP/YjgQ family DUF4175 PF13779.1 CDI85080.1 - 4.7 4.7 33.3 5 4.7 23.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) DUF3038 PF11237.3 CDI85080.1 - 4.9 6.9 17.8 5.8 6.6 12.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3038) WASH-7_C PF14746.1 CDI85080.1 - 5.1 6.6 11.5 6.9 6.2 8.0 1.3 1 0 0 1 1 1 0 WASH complex subunit 7, C-terminal DUF3708 PF12501.3 CDI85080.1 - 5.5 6.7 5.6 6 6.6 3.9 1.1 1 0 0 1 1 1 0 Phosphate ATP-binding cassette transporter Ctr PF04145.10 CDI85080.1 - 6.1 6.8 6.4 6.3 6.8 4.4 1.1 1 0 0 1 1 1 0 Ctr copper transporter family RR_TM4-6 PF06459.7 CDI85080.1 - 6.4 6.5 9.2 7 6.4 6.4 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Hira PF07569.6 CDI85080.1 - 6.4 5.9 9.8 7 5.7 6.8 1.0 1 0 0 1 1 1 0 TUP1-like enhancer of split DUF4404 PF14357.1 CDI85080.1 - 6.9 7.1 17.8 9.4 6.7 12.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4404) Bestrophin PF01062.16 CDI85080.1 - 7.1 5.4 9.4 7.1 5.4 6.5 1.0 1 0 0 1 1 1 0 Bestrophin, RFP-TM, chloride channel DDE_Tnp_IS66 PF03050.9 CDI85080.1 - 7.1 5.7 12.9 8.2 5.5 8.9 1.0 1 0 0 1 1 1 0 Transposase IS66 family SopA_C PF13979.1 CDI85080.1 - 7.4 6.1 10.7 8.1 6.0 7.4 1.2 1 0 0 1 1 1 0 SopA-like catalytic domain EIIBC-GUT_N PF03612.9 CDI85080.1 - 7.4 6.1 6.9 8.1 6.0 4.8 1.1 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus OATP PF03137.15 CDI85080.1 - 7.4 4.4 11.4 7.6 4.4 7.9 1.0 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family PAT1 PF09770.4 CDI85080.1 - 7.8 4.6 30.6 8.3 4.5 21.2 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 FHIPEP PF00771.15 CDI85080.1 - 7.9 4.6 9.9 8.2 4.6 6.8 1.0 1 0 0 1 1 1 0 FHIPEP family DUF3276 PF11680.3 CDI85080.1 - 8.2 6.2 9.0 10 5.9 6.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3276) CRF1 PF10380.4 CDI85080.1 - 8.7 6.7 8.1 9.4 6.5 5.6 1.1 1 0 0 1 1 1 0 Transcription factor CRF1 DUF4199 PF13858.1 CDI85080.1 - 9 6.1 6.9 11 5.8 4.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) DUF4557 PF15101.1 CDI85080.1 - 9.1 6.0 21.5 10 5.8 14.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) Suf PF05843.9 CDI85081.1 - 0.0083 15.8 11.7 0.0079 15.9 8.1 1.2 1 0 0 1 1 1 1 Suppressor of forked protein (Suf) Spt20 PF12090.3 CDI85081.1 - 0.022 14.1 5.6 0.031 13.6 3.9 1.4 1 0 0 1 1 1 0 Spt20 family Med15 PF09606.5 CDI85081.1 - 0.092 10.9 36.0 0.11 10.7 25.0 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal PRP3 PF08572.5 CDI85081.1 - 0.44 9.8 14.5 0.74 9.1 10.1 1.4 1 0 0 1 1 1 0 pre-mRNA processing factor 3 (PRP3) RR_TM4-6 PF06459.7 CDI85081.1 - 0.63 9.8 8.4 0.71 9.7 5.8 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 PAT1 PF09770.4 CDI85081.1 - 0.84 7.8 28.2 0.73 7.9 19.5 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Apt1 PF10351.4 CDI85081.1 - 1.1 7.9 7.1 1.1 7.9 4.9 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain FimP PF09766.4 CDI85081.1 - 1.3 8.0 17.2 1.6 7.7 11.9 1.1 1 0 0 1 1 1 0 Fms-interacting protein Presenilin PF01080.12 CDI85081.1 - 1.5 7.5 6.0 1.5 7.5 4.1 1.1 1 0 0 1 1 1 0 Presenilin DUF4175 PF13779.1 CDI85081.1 - 4.3 4.9 29.6 5.5 4.5 20.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Serinc PF03348.10 CDI85081.1 - 5 5.7 8.7 5.7 5.5 6.0 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) FLO_LFY PF01698.11 CDI85081.1 - 5.2 5.8 9.1 6.7 5.4 6.3 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein CDC45 PF02724.9 CDI85081.1 - 5.5 4.8 9.5 6.3 4.6 6.6 1.0 1 0 0 1 1 1 0 CDC45-like protein TFIIA PF03153.8 CDI85081.1 - 5.8 6.7 27.8 7.2 6.4 19.3 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Hid1 PF12722.2 CDI85081.1 - 8.1 3.9 11.1 8.8 3.8 7.7 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein AUX_IAA PF02309.11 CDI85081.1 - 9.4 5.9 10.6 13 5.4 7.4 1.3 1 0 0 1 1 1 0 AUX/IAA family DUF4407 PF14362.1 CDI85081.1 - 9.6 5.0 12.2 12 4.7 8.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) RimM PF01782.13 CDI85082.1 - 0.028 14.3 0.1 0.22 11.4 0.1 2.7 1 0 0 1 1 1 0 RimM N-terminal domain Gemini_AC4_5_2 PF08464.5 CDI85082.1 - 0.13 12.0 0.1 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 Geminivirus AC4/5 conserved region DUF2802 PF10975.3 CDI85083.1 - 0.13 11.9 12.9 0.2 11.4 8.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2802) GRP PF07172.6 CDI85083.1 - 0.2 12.1 5.7 0.28 11.6 4.0 1.3 1 0 0 1 1 1 0 Glycine rich protein family Med15 PF09606.5 CDI85083.1 - 0.7 8.0 21.1 0.79 7.8 14.6 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal FAM222A PF15258.1 CDI85083.1 - 1.8 7.7 12.2 1.9 7.5 8.5 1.0 1 0 0 1 1 1 0 Protein family of FAM222A PAT1 PF09770.4 CDI85083.1 - 2.4 6.2 20.8 2.7 6.1 14.4 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 PhnG PF06754.7 CDI85083.1 - 3.1 7.3 5.8 5.3 6.6 4.0 1.3 1 0 0 1 1 1 0 Phosphonate metabolism protein PhnG FYDLN_acid PF09538.5 CDI85084.1 - 0.18 12.3 9.9 0.29 11.7 6.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) RIC3 PF15361.1 CDI85084.1 - 0.3 11.3 24.0 0.37 11.0 16.6 1.1 1 0 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 DUF1510 PF07423.6 CDI85084.1 - 0.35 10.2 24.7 0.42 9.9 17.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) FNIP_N PF14636.1 CDI85084.1 - 0.47 10.9 23.9 0.5 10.8 16.6 1.0 1 0 0 1 1 1 0 Folliculin-interacting protein N-terminus CDC45 PF02724.9 CDI85084.1 - 0.92 7.4 21.5 1 7.3 14.9 1.0 1 0 0 1 1 1 0 CDC45-like protein SprA-related PF12118.3 CDI85084.1 - 1.1 8.5 52.8 1.4 8.1 36.6 1.1 1 0 0 1 1 1 0 SprA-related family Spore_coat_CotO PF14153.1 CDI85084.1 - 1.1 8.6 35.4 1.3 8.4 24.5 1.0 1 0 0 1 1 1 0 Spore coat protein CotO Raftlin PF15250.1 CDI85084.1 - 1.5 7.2 22.2 1.5 7.2 15.4 1.0 1 0 0 1 1 1 0 Raftlin DDRGK PF09756.4 CDI85084.1 - 2.4 7.5 33.4 2.6 7.3 23.2 1.0 1 0 0 1 1 1 0 DDRGK domain NARP1 PF12569.3 CDI85084.1 - 2.6 6.6 23.2 3 6.5 16.1 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 NPR3 PF03666.8 CDI85084.1 - 2.7 6.4 25.0 3.2 6.1 17.3 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF913 PF06025.7 CDI85084.1 - 2.8 6.6 14.5 3.3 6.3 10.1 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) CPSF100_C PF13299.1 CDI85084.1 - 3 8.0 20.7 3.3 7.8 14.4 1.1 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal DUF2370 PF10176.4 CDI85084.1 - 3.2 7.0 14.5 4.6 6.5 10.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) HCO3_cotransp PF00955.16 CDI85084.1 - 3.3 6.2 11.1 3.2 6.3 7.7 1.0 1 0 0 1 1 1 0 HCO3- transporter family Serinc PF03348.10 CDI85084.1 - 4.5 5.8 19.4 6.6 5.3 13.5 1.4 1 0 0 1 1 1 0 Serine incorporator (Serinc) Tim54 PF11711.3 CDI85084.1 - 4.8 5.6 18.3 5.5 5.4 12.7 1.0 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Rtf2 PF04641.7 CDI85084.1 - 4.8 6.3 23.5 5.9 6.0 16.3 1.0 1 0 0 1 1 1 0 Rtf2 RING-finger DDHD PF02862.12 CDI85084.1 - 4.9 6.8 22.5 5.5 6.7 15.6 1.1 1 0 0 1 1 1 0 DDHD domain DUF4045 PF13254.1 CDI85084.1 - 5 6.3 22.6 5.9 6.0 15.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Paramyxo_ncap PF00973.14 CDI85084.1 - 5.3 5.6 21.2 5.7 5.5 14.7 1.0 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein RR_TM4-6 PF06459.7 CDI85084.1 - 5.4 6.8 27.7 6.4 6.5 19.2 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DHHW PF14286.1 CDI85084.1 - 6.6 5.9 21.9 7.9 5.6 15.2 1.0 1 0 0 1 1 1 0 DHHW protein Pox_Ag35 PF03286.9 CDI85084.1 - 7.1 6.1 17.5 8.3 5.8 12.1 1.0 1 0 0 1 1 1 0 Pox virus Ag35 surface protein SAPS PF04499.10 CDI85084.1 - 7.7 5.0 22.1 8 4.9 15.3 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF4220 PF13968.1 CDI85084.1 - 7.7 5.5 14.8 8.6 5.3 10.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4220) Zip PF02535.17 CDI85084.1 - 8.1 5.3 18.0 11 4.9 12.5 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Spore_YhcN_YlaJ PF09580.5 CDI85085.1 - 2e-05 24.7 4.9 2e-05 24.7 3.4 1.1 1 0 0 1 1 1 1 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) Anoctamin PF04547.7 CDI85085.1 - 0.03 12.9 0.9 0.027 13.1 0.6 1.1 1 0 0 1 1 1 0 Calcium-activated chloride channel RIC3 PF15361.1 CDI85085.1 - 0.033 14.4 14.0 0.06 13.5 9.7 1.4 1 0 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 SAGA-Tad1 PF12767.2 CDI85085.1 - 0.035 13.7 14.4 0.045 13.4 10.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit NARP1 PF12569.3 CDI85085.1 - 0.038 12.7 22.4 0.023 13.4 14.3 1.4 2 0 0 2 2 2 0 NMDA receptor-regulated protein 1 RR_TM4-6 PF06459.7 CDI85085.1 - 0.051 13.4 19.0 0.071 13.0 13.1 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Zip PF02535.17 CDI85085.1 - 0.099 11.6 3.7 0.11 11.4 2.6 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter AUX_IAA PF02309.11 CDI85085.1 - 0.14 11.9 11.9 0.2 11.3 8.2 1.2 1 0 0 1 1 1 0 AUX/IAA family Tim54 PF11711.3 CDI85085.1 - 0.16 10.5 11.4 0.19 10.2 7.9 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 NPR3 PF03666.8 CDI85085.1 - 0.17 10.4 14.2 0.21 10.0 9.8 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Raftlin PF15250.1 CDI85085.1 - 0.17 10.3 13.4 0.2 10.1 9.3 1.1 1 0 0 1 1 1 0 Raftlin DUF4045 PF13254.1 CDI85085.1 - 0.18 11.0 14.7 0.24 10.6 10.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) DDHD PF02862.12 CDI85085.1 - 0.22 11.2 14.8 0.29 10.8 10.2 1.2 1 0 0 1 1 1 0 DDHD domain Asp-B-Hydro_N PF05279.6 CDI85085.1 - 0.24 11.2 18.6 0.25 11.1 12.9 1.2 1 1 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region DUF2201_N PF13203.1 CDI85085.1 - 0.3 10.2 17.8 0.5 9.4 12.3 1.3 1 0 0 1 1 1 0 Putative metallopeptidase domain Daxx PF03344.10 CDI85085.1 - 0.3 9.5 18.9 0.36 9.2 13.1 1.1 1 0 0 1 1 1 0 Daxx Family DUF1510 PF07423.6 CDI85085.1 - 0.36 10.1 22.2 0.47 9.7 15.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DUF853 PF05872.7 CDI85085.1 - 0.57 8.4 11.0 0.7 8.1 7.7 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) DUF4407 PF14362.1 CDI85085.1 - 0.59 9.0 19.0 0.93 8.3 13.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Lipoprotein_X PF03305.8 CDI85085.1 - 0.64 9.3 11.7 0.81 9.0 8.1 1.1 1 0 0 1 1 1 0 Mycoplasma MG185/MG260 protein Band_3_cyto PF07565.8 CDI85085.1 - 0.72 9.3 17.5 1 8.8 12.1 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain DUF4557 PF15101.1 CDI85085.1 - 0.75 9.6 26.4 1.1 9.0 18.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) MDMPI_N PF11716.3 CDI85085.1 - 0.79 10.1 3.8 0.32 11.4 0.9 1.7 2 0 0 2 2 1 0 Mycothiol maleylpyruvate isomerase N-terminal domain CDC45 PF02724.9 CDI85085.1 - 0.85 7.5 18.3 1.2 7.1 12.7 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF2052 PF09747.4 CDI85085.1 - 0.86 9.5 26.1 1.2 8.9 18.1 1.1 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) DUF4613 PF15390.1 CDI85085.1 - 0.98 7.5 13.0 1.2 7.1 9.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) SUFU_C PF12470.3 CDI85085.1 - 1 8.8 8.1 1.4 8.4 5.6 1.1 1 0 0 1 1 1 0 Suppressor of Fused Gli/Ci N terminal binding domain AAA_23 PF13476.1 CDI85085.1 - 1.1 9.5 22.2 1.7 8.9 15.4 1.3 1 0 0 1 1 1 0 AAA domain Vfa1 PF08432.5 CDI85085.1 - 1.2 9.0 20.7 2.2 8.2 14.3 1.4 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF913 PF06025.7 CDI85085.1 - 1.3 7.7 10.0 1.6 7.4 6.9 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DUF605 PF04652.11 CDI85085.1 - 1.3 8.3 29.4 1.7 7.9 20.4 1.1 1 0 0 1 1 1 0 Vta1 like Gti1_Pac2 PF09729.4 CDI85085.1 - 1.3 8.8 11.4 1.9 8.3 7.9 1.2 1 0 0 1 1 1 0 Gti1/Pac2 family Pex14_N PF04695.8 CDI85085.1 - 1.4 9.0 25.2 0.19 11.7 13.1 2.1 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region FLO_LFY PF01698.11 CDI85085.1 - 1.4 7.6 16.1 1.9 7.2 11.2 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein Ycf1 PF05758.7 CDI85085.1 - 1.6 6.3 19.7 2 6.0 13.7 1.0 1 0 0 1 1 1 0 Ycf1 SPX PF03105.14 CDI85085.1 - 1.8 8.2 17.3 2.6 7.7 12.0 1.2 1 0 0 1 1 1 0 SPX domain Borrelia_P83 PF05262.6 CDI85085.1 - 1.8 6.7 20.9 2.1 6.5 14.5 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein eIF-3_zeta PF05091.7 CDI85085.1 - 2.1 6.8 22.1 2.5 6.6 15.3 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF2072 PF09845.4 CDI85085.1 - 2.5 8.0 11.8 4.7 7.1 8.2 1.4 1 0 0 1 1 1 0 Zn-ribbon containing protein (DUF2072) Rtf2 PF04641.7 CDI85085.1 - 2.8 7.0 19.5 3.7 6.6 13.6 1.2 1 0 0 1 1 1 0 Rtf2 RING-finger DUF4175 PF13779.1 CDI85085.1 - 2.8 5.5 52.0 3.6 5.1 36.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) HemX PF04375.9 CDI85085.1 - 2.9 6.3 28.1 4.1 5.9 19.5 1.2 1 0 0 1 1 1 0 HemX Hom_end_hint PF05203.11 CDI85085.1 - 2.9 7.5 11.2 4.4 6.9 7.8 1.2 1 0 0 1 1 1 0 Hom_end-associated Hint Cellulose_synt PF03552.9 CDI85085.1 - 3 6.0 7.8 3.5 5.8 5.4 1.1 1 0 0 1 1 1 0 Cellulose synthase FYDLN_acid PF09538.5 CDI85085.1 - 3.2 8.3 11.8 5.6 7.5 8.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) GAGA_bind PF06217.7 CDI85085.1 - 4 7.3 16.5 5.3 6.9 11.5 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family Pal1 PF08316.6 CDI85085.1 - 4.4 7.7 10.1 7.7 6.9 7.0 1.4 1 0 0 1 1 1 0 Pal1 cell morphology protein SAPS PF04499.10 CDI85085.1 - 4.5 5.8 16.2 5.6 5.4 11.3 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein BTV_NS2 PF04514.7 CDI85085.1 - 4.7 5.9 15.7 5.9 5.6 10.8 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Dynamin_N PF00350.18 CDI85085.1 - 5.1 6.8 9.6 9.1 6.0 6.7 1.4 1 0 0 1 1 1 0 Dynamin family DUF2126 PF09899.4 CDI85085.1 - 5.1 4.9 13.6 6.6 4.6 9.4 1.1 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) CPSF100_C PF13299.1 CDI85085.1 - 5.2 7.2 16.5 7.6 6.6 11.5 1.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal HSP70 PF00012.15 CDI85085.1 - 6.1 4.6 18.4 8 4.2 12.7 1.1 1 0 0 1 1 1 0 Hsp70 protein DUF4011 PF13195.1 CDI85085.1 - 6.8 6.6 13.7 12 5.9 9.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4011) FAM60A PF15396.1 CDI85085.1 - 7 6.3 14.0 10 5.8 9.7 1.2 1 0 0 1 1 1 0 Protein Family FAM60A PIH1 PF08190.7 CDI85085.1 - 7.9 5.8 23.1 11 5.3 16.0 1.2 1 0 0 1 1 1 0 pre-RNA processing PIH1/Nop17 GvpL_GvpF PF06386.6 CDI85085.1 - 8.4 5.8 18.3 13 5.2 12.7 1.3 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF DUF1764 PF08576.5 CDI85085.1 - 8.9 7.1 22.2 21 5.9 15.4 1.6 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) Folate_carrier PF01770.13 CDI85085.1 - 9.5 4.6 12.4 12 4.2 8.6 1.1 1 0 0 1 1 1 0 Reduced folate carrier PAT1 PF09770.4 CDI85086.1 - 0.00032 19.1 12.9 0.00032 19.1 8.9 2.2 2 0 0 2 2 2 1 Topoisomerase II-associated protein PAT1 Collagen PF01391.13 CDI85086.1 - 0.0019 17.6 25.5 0.0019 17.6 17.7 3.7 2 1 1 3 3 3 1 Collagen triple helix repeat (20 copies) Spt20 PF12090.3 CDI85086.1 - 0.087 12.1 6.4 0.34 10.2 0.6 2.2 2 0 0 2 2 2 0 Spt20 family Phostensin_N PF13916.1 CDI85086.1 - 3.1 7.8 12.8 1.8 8.6 1.1 3.2 2 0 0 2 2 2 0 PP1-regulatory protein, Phostensin N-terminal SR-25 PF10500.4 CDI85087.1 - 0.017 14.5 21.1 0.019 14.4 14.6 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein FimP PF09766.4 CDI85088.1 - 0.00057 19.0 37.8 0.0023 17.0 3.9 2.0 2 0 0 2 2 2 2 Fms-interacting protein Pex14_N PF04695.8 CDI85088.1 - 0.0026 17.8 35.0 0.025 14.6 6.0 2.1 2 0 0 2 2 2 2 Peroxisomal membrane anchor protein (Pex14p) conserved region Otopetrin PF03189.8 CDI85088.1 - 0.0084 15.1 0.0 0.11 11.4 0.0 1.9 2 0 0 2 2 2 1 Otopetrin Neur_chan_memb PF02932.11 CDI85088.1 - 0.0092 15.8 5.2 0.031 14.1 3.6 1.7 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region N6_N4_Mtase PF01555.13 CDI85088.1 - 0.043 13.3 0.0 0.33 10.3 0.0 2.0 1 1 0 1 1 1 0 DNA methylase zf-DHHC PF01529.15 CDI85088.1 - 0.052 12.9 9.9 0.16 11.3 0.0 2.1 2 0 0 2 2 1 0 DHHC palmitoyltransferase Suf PF05843.9 CDI85088.1 - 0.1 12.3 31.8 0.18 11.5 5.8 2.1 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) TFIIA PF03153.8 CDI85088.1 - 0.12 12.1 37.3 0.18 11.6 6.8 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit DUF2052 PF09747.4 CDI85088.1 - 0.15 12.0 22.4 0.27 11.1 0.6 2.1 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) DUF3371 PF11851.3 CDI85088.1 - 0.31 11.7 31.1 0.89 10.2 6.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3371) GOLD_2 PF13897.1 CDI85088.1 - 0.37 11.0 10.3 1 9.5 3.5 2.1 2 0 0 2 2 2 0 Golgi-dynamics membrane-trafficking TMEM51 PF15345.1 CDI85088.1 - 0.59 9.7 22.6 0.87 9.2 7.4 2.1 2 0 0 2 2 2 0 Transmembrane protein 51 Spt20 PF12090.3 CDI85088.1 - 1 8.7 30.9 0.1 11.9 3.7 2.3 2 0 0 2 2 2 0 Spt20 family Ctr PF04145.10 CDI85088.1 - 1 9.4 15.6 1.4 8.9 0.5 2.1 2 0 0 2 2 2 0 Ctr copper transporter family RED_N PF07808.8 CDI85088.1 - 1 8.4 34.7 0.52 9.4 12.1 2.0 2 0 0 2 2 2 0 RED-like protein N-terminal region Dala_Dala_lig_N PF01820.16 CDI85088.1 - 1.1 9.5 11.0 5.9 7.2 0.1 2.2 2 0 0 2 2 2 0 D-ala D-ala ligase N-terminus DUF2899 PF11449.3 CDI85088.1 - 1.2 8.2 4.1 5.6 6.0 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2899) DUF4557 PF15101.1 CDI85088.1 - 1.2 8.9 41.7 0.78 9.5 15.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4557) Peroxin-13_N PF04088.8 CDI85088.1 - 2.4 8.0 14.0 6.7 6.6 4.5 2.1 2 0 0 2 2 2 0 Peroxin 13, N-terminal region Raftlin PF15250.1 CDI85088.1 - 2.5 6.5 19.3 1.3 7.5 0.8 2.0 2 0 0 2 2 2 0 Raftlin DUF2956 PF11169.3 CDI85088.1 - 2.5 8.0 33.1 3.6 7.6 12.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2956) Tim54 PF11711.3 CDI85088.1 - 2.7 6.4 15.3 2.5 6.5 3.9 2.1 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 CDC45 PF02724.9 CDI85088.1 - 2.8 5.8 16.9 2.9 5.8 0.3 2.0 2 0 0 2 2 2 0 CDC45-like protein Trypan_glycop_C PF10659.4 CDI85088.1 - 3.7 7.8 22.4 1.3 9.3 7.7 2.2 2 0 0 2 2 2 0 Trypanosome variant surface glycoprotein C-terminal domain AIF_C PF14721.1 CDI85088.1 - 4.2 7.6 23.5 0.79 9.9 2.4 2.2 2 0 0 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Med15 PF09606.5 CDI85088.1 - 4.3 5.4 72.6 0.94 7.5 18.0 2.3 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal PAT1 PF09770.4 CDI85088.1 - 4.6 5.3 54.0 0.92 7.6 11.6 2.0 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 DUF2413 PF10310.4 CDI85088.1 - 7.5 5.2 26.7 1.5 7.5 8.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2413) DUF3899 PF13038.1 CDI85088.1 - 8 6.6 5.2 62 3.8 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3899) DUF4011 PF13195.1 CDI85088.1 - 8.2 6.3 16.3 4 7.4 4.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4011) DUF4366 PF14283.1 CDI85088.1 - 8.3 5.7 13.9 3.6 6.9 0.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4366) BRF1 PF07741.8 CDI85088.1 - 8.4 6.6 23.9 4.3 7.6 2.9 2.3 2 0 0 2 2 2 0 Brf1-like TBP-binding domain FAM60A PF15396.1 CDI85088.1 - 9.3 5.9 18.0 3.7 7.2 0.9 2.1 2 0 0 2 2 2 0 Protein Family FAM60A Trp_oprn_chp PF09534.5 CDI85088.1 - 9.9 5.7 12.3 0.16 11.5 0.4 2.2 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) SprA-related PF12118.3 CDI85089.1 - 0.0043 16.4 53.6 0.023 14.0 17.6 2.2 2 0 0 2 2 2 2 SprA-related family Ribosomal_60s PF00428.14 CDI85089.1 - 0.0073 16.6 14.5 0.16 12.3 4.2 2.4 2 0 0 2 2 2 2 60s Acidic ribosomal protein Shadoo PF14999.1 CDI85089.1 - 0.18 11.6 8.6 3.4 7.5 2.8 2.2 2 0 0 2 2 2 0 Shadow of prion protein, neuroprotective Band_3_cyto PF07565.8 CDI85089.1 - 5.5 6.4 26.3 0.2 11.1 5.0 2.1 2 0 0 2 2 2 0 Band 3 cytoplasmic domain PAT1 PF09770.4 CDI85091.1 - 2.5 6.2 61.1 2.6 6.1 42.3 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF4080 PF13311.1 CDI85091.1 - 7.7 6.5 25.9 2.1 8.3 6.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF4080) DUF2422 PF10337.4 CDI85091.1 - 8.4 5.0 25.7 9.6 4.8 17.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2422) PLRV_ORF5 PF01690.12 CDI85094.1 - 0.77 8.8 19.3 0.37 9.8 7.1 2.2 2 0 0 2 2 2 0 Potato leaf roll virus readthrough protein Cyt-b5 PF00173.23 CDI85095.1 - 1.5e-06 27.8 0.0 4.3e-06 26.4 0.0 1.8 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain SR-25 PF10500.4 CDI85095.1 - 2.9e-05 23.6 3.0 2.9e-05 23.6 2.1 2.4 3 0 0 3 3 3 1 Nuclear RNA-splicing-associated protein Corona_nucleoca PF00937.13 CDI85095.1 - 3.9 6.3 8.2 6.5 5.5 5.7 1.3 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein Hamartin PF04388.7 CDI85096.1 - 9.7 4.7 12.6 11 4.5 8.7 1.1 1 0 0 1 1 1 0 Hamartin protein Baculo_PP31 PF05311.6 CDI85097.1 - 0.7 9.1 5.7 0.73 9.0 3.9 1.0 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) RskA PF10099.4 CDI85097.1 - 0.83 9.3 13.0 1.1 8.9 9.0 1.3 1 0 0 1 1 1 0 Anti-sigma-K factor rskA R_equi_Vir PF05526.6 CDI85097.1 - 3.5 7.2 9.6 4.1 7.0 6.7 1.1 1 0 0 1 1 1 0 Rhodococcus equi virulence-associated protein Gastrin PF00918.12 CDI85097.1 - 5 7.9 8.0 5.8 7.7 5.6 1.1 1 0 0 1 1 1 0 Gastrin/cholecystokinin family UCH PF00443.24 CDI85098.1 - 6.9e-23 81.1 0.0 6.9e-23 81.1 0.0 2.5 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CDI85098.1 - 0.0063 15.9 0.0 0.0063 15.9 0.0 3.5 3 1 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase Dala_Dala_lig_N PF01820.16 CDI85098.1 - 0.11 12.8 0.4 0.11 12.8 0.2 4.2 3 1 2 5 5 5 0 D-ala D-ala ligase N-terminus DUF3159 PF11361.3 CDI85100.1 - 0.0001 21.8 0.3 0.00013 21.5 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3159) OATP PF03137.15 CDI85100.1 - 0.17 9.9 0.1 0.26 9.3 0.1 1.2 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family IncA PF04156.9 CDI85101.1 - 0.0066 16.0 15.3 0.0066 16.0 10.6 3.7 4 0 0 4 4 1 1 IncA protein Gti1_Pac2 PF09729.4 CDI85101.1 - 0.0082 16.0 0.4 0.01 15.6 0.3 1.3 1 0 0 1 1 1 1 Gti1/Pac2 family FimP PF09766.4 CDI85101.1 - 0.0096 15.0 17.5 0.013 14.6 12.2 1.1 1 0 0 1 1 1 1 Fms-interacting protein Folate_carrier PF01770.13 CDI85101.1 - 0.011 14.2 8.1 0.024 13.1 5.6 1.5 1 0 0 1 1 1 0 Reduced folate carrier CD20 PF04103.10 CDI85101.1 - 0.03 14.2 1.5 0.03 14.2 1.1 2.1 2 0 0 2 2 1 0 CD20-like family Pex16 PF08610.5 CDI85101.1 - 0.047 12.6 8.9 0.064 12.2 6.2 1.1 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) FAM176 PF14851.1 CDI85101.1 - 0.078 12.6 3.6 0.14 11.8 2.5 1.3 1 0 0 1 1 1 0 FAM176 family Mgr1 PF08602.5 CDI85101.1 - 0.088 11.8 1.4 0.11 11.4 1.0 1.1 1 0 0 1 1 1 0 Mgr1-like, i-AAA protease complex subunit YfhO PF09586.5 CDI85101.1 - 0.17 9.8 4.1 0.21 9.5 2.8 1.1 1 0 0 1 1 1 0 Bacterial membrane protein YfhO MRF_C2 PF13888.1 CDI85101.1 - 0.26 11.0 10.0 1.9 8.3 4.6 2.3 2 0 0 2 2 2 0 Myelin gene regulatory factor C-terminal domain 2 SeqA PF03925.8 CDI85101.1 - 0.27 10.9 9.9 0.49 10.0 6.9 1.4 1 0 0 1 1 1 0 SeqA protein Band_3_cyto PF07565.8 CDI85101.1 - 0.31 10.5 9.6 0.4 10.1 6.6 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Suf PF05843.9 CDI85101.1 - 0.35 10.5 17.7 0.47 10.1 12.3 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF2217 PF10265.4 CDI85101.1 - 0.35 9.5 10.3 0.66 8.6 7.1 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) Dala_Dala_lig_N PF01820.16 CDI85101.1 - 0.52 10.6 4.0 1.2 9.4 2.8 1.6 1 0 0 1 1 1 0 D-ala D-ala ligase N-terminus eIF-3_zeta PF05091.7 CDI85101.1 - 0.62 8.6 13.1 0.77 8.3 9.1 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) OATP PF03137.15 CDI85101.1 - 0.69 7.8 8.1 0.98 7.3 5.6 1.2 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Neur_chan_memb PF02932.11 CDI85101.1 - 0.71 9.7 4.9 0.83 9.4 3.4 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region UPF0560 PF10577.4 CDI85101.1 - 0.76 7.9 17.5 1.1 7.4 12.1 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 DUF2232 PF09991.4 CDI85101.1 - 0.97 8.3 14.5 0.096 11.6 5.2 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2232) ICE2 PF08426.5 CDI85101.1 - 1 7.8 3.3 1.4 7.4 2.3 1.2 1 0 0 1 1 1 0 ICE2 Cellulose_synt PF03552.9 CDI85101.1 - 1.1 7.5 3.1 1.3 7.2 2.2 1.1 1 0 0 1 1 1 0 Cellulose synthase AUX_IAA PF02309.11 CDI85101.1 - 1.1 8.9 8.2 1.7 8.3 5.7 1.3 1 0 0 1 1 1 0 AUX/IAA family Serinc PF03348.10 CDI85101.1 - 1.2 7.7 11.9 1.7 7.2 8.2 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) DUF4199 PF13858.1 CDI85101.1 - 1.2 9.0 11.4 0.23 11.3 4.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4199) CDK5_activator PF03261.10 CDI85101.1 - 1.3 8.3 13.0 1.8 7.8 9.0 1.4 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein DUF106 PF01956.11 CDI85101.1 - 1.7 8.1 9.5 2.7 7.5 6.6 1.2 1 0 0 1 1 1 0 Integral membrane protein DUF106 Hid1 PF12722.2 CDI85101.1 - 2.8 5.5 11.9 3.6 5.1 8.3 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DDHD PF02862.12 CDI85101.1 - 2.8 7.6 11.0 4.5 6.9 7.7 1.4 1 0 0 1 1 1 0 DDHD domain Glyco_transf_15 PF01793.11 CDI85101.1 - 3.1 6.6 9.0 4.6 6.0 6.2 1.2 1 0 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase Draxin PF15550.1 CDI85101.1 - 3.2 7.3 15.9 2.2 7.8 10.2 1.4 1 1 0 1 1 1 0 Draxin Herpes_UL87 PF03043.9 CDI85101.1 - 3.8 5.7 11.2 5.4 5.2 7.7 1.2 1 0 0 1 1 1 0 Herpesvirus UL87 family Baculo_PP31 PF05311.6 CDI85101.1 - 4 6.6 11.5 5.7 6.1 7.9 1.2 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) Peptidase_U57 PF05582.7 CDI85101.1 - 6.3 5.6 9.1 8.7 5.2 6.3 1.2 1 0 0 1 1 1 0 YabG peptidase U57 AAA_23 PF13476.1 CDI85101.1 - 6.9 6.9 15.9 9 6.5 11.0 1.1 1 0 0 1 1 1 0 AAA domain Insulin PF00049.13 CDI85101.1 - 7.9 7.3 10.6 19 6.1 7.3 1.6 1 0 0 1 1 1 0 Insulin/IGF/Relaxin family MIP-T3 PF10243.4 CDI85103.1 - 3.9 5.8 67.5 3.9 5.8 46.8 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 CAF-1_p150 PF11600.3 CDI85103.1 - 9.2 5.5 77.7 12 5.1 53.8 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal SR-25 PF10500.4 CDI85104.1 - 1.4e-05 24.7 13.6 1.4e-05 24.7 9.4 4.6 5 1 0 5 5 5 2 Nuclear RNA-splicing-associated protein PBP1_TM PF14812.1 CDI85104.1 - 3.9 7.8 20.2 2.6 8.3 0.8 4.5 4 0 0 4 4 4 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Activator_LAG-3 PF11498.3 CDI85106.1 - 2e-05 23.5 27.5 2.2e-05 23.3 19.1 1.3 1 0 0 1 1 1 1 Transcriptional activator LAG-3 Nop53 PF07767.6 CDI85106.1 - 0.032 13.2 26.0 0.041 12.8 18.0 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) PAT1 PF09770.4 CDI85106.1 - 0.15 10.3 23.5 0.16 10.1 16.3 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 FAM222A PF15258.1 CDI85106.1 - 0.21 10.7 20.8 0.28 10.3 14.4 1.1 1 0 0 1 1 1 0 Protein family of FAM222A TT_ORF1 PF02956.9 CDI85106.1 - 0.48 8.8 9.7 0.58 8.5 6.7 1.1 1 0 0 1 1 1 0 TT viral orf 1 Mucin PF01456.12 CDI85106.1 - 1.2 8.9 16.0 2.3 8.0 11.1 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein Daxx PF03344.10 CDI85106.1 - 1.3 7.3 27.7 1.8 6.9 19.2 1.2 1 0 0 1 1 1 0 Daxx Family DUF2946 PF11162.3 CDI85106.1 - 1.4 9.1 12.5 1.3 9.2 7.8 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2946) Ycf1 PF05758.7 CDI85106.1 - 4 5.0 14.5 3.9 5.0 10.0 1.1 1 0 0 1 1 1 0 Ycf1 CDC45 PF02724.9 CDI85106.1 - 4.1 5.3 23.8 5.5 4.9 16.5 1.1 1 0 0 1 1 1 0 CDC45-like protein SOBP PF15279.1 CDI85106.1 - 7.2 6.8 15.2 10 6.4 10.5 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein YjgP_YjgQ PF03739.9 CDI85106.1 - 7.3 5.2 5.6 8.4 5.0 3.9 1.1 1 0 0 1 1 1 0 Predicted permease YjgP/YjgQ family SOBP PF15279.1 CDI85107.1 - 0.071 13.4 33.3 0.8 10.0 10.3 2.4 2 0 0 2 2 2 0 Sine oculis-binding protein Cwf_Cwc_15 PF04889.7 CDI85107.1 - 1.5 8.5 28.8 0.055 13.1 1.0 3.4 3 0 0 3 3 3 0 Cwf15/Cwc15 cell cycle control protein RAP1 PF07218.6 CDI85107.1 - 2.4 6.1 14.6 4.4 5.2 10.1 1.4 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Spore_coat_CotO PF14153.1 CDI85107.1 - 3.8 6.8 32.4 0.017 14.5 6.8 3.3 3 0 0 3 3 3 0 Spore coat protein CotO DUF572 PF04502.8 CDI85107.1 - 4.7 6.3 37.8 1.3 8.1 9.4 3.4 3 0 0 3 3 3 0 Family of unknown function (DUF572) AAA_23 PF13476.1 CDI85107.1 - 7.7 6.7 25.6 9 6.5 1.1 2.4 2 0 0 2 2 2 0 AAA domain zf-DHHC PF01529.15 CDI85108.1 - 0.31 10.3 6.4 2.2 7.6 0.1 2.2 2 0 0 2 2 2 0 DHHC palmitoyltransferase Med15 PF09606.5 CDI85108.1 - 0.38 8.9 90.5 0.52 8.4 62.7 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Peptidase_S49_N PF08496.5 CDI85108.1 - 6.8 6.4 19.9 0.25 11.1 3.0 2.4 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Rifin_STEVOR PF02009.11 CDI85109.1 - 5 6.6 8.1 5.2 6.6 5.6 1.1 1 0 0 1 1 1 0 Rifin/stevor family SprA-related PF12118.3 CDI85110.1 - 0.0093 15.3 30.8 0.011 15.0 21.3 1.2 1 0 0 1 1 1 1 SprA-related family Suf PF05843.9 CDI85110.1 - 0.021 14.5 19.0 0.029 14.0 13.2 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) EIF4E-T PF10477.4 CDI85110.1 - 0.34 9.6 15.5 0.35 9.6 10.8 1.0 1 0 0 1 1 1 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E RR_TM4-6 PF06459.7 CDI85110.1 - 0.44 10.4 13.6 0.53 10.1 9.4 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 FLO_LFY PF01698.11 CDI85110.1 - 1.1 8.0 13.1 1.3 7.8 9.1 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein FAM60A PF15396.1 CDI85110.1 - 1.5 8.5 11.6 1.9 8.2 8.0 1.1 1 0 0 1 1 1 0 Protein Family FAM60A TFIIA PF03153.8 CDI85110.1 - 1.7 8.4 33.1 2 8.2 22.9 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF605 PF04652.11 CDI85110.1 - 2.2 7.6 28.0 2.7 7.2 19.4 1.1 1 0 0 1 1 1 0 Vta1 like Raftlin PF15250.1 CDI85110.1 - 2.5 6.5 14.0 3 6.2 9.7 1.1 1 0 0 1 1 1 0 Raftlin Hid1 PF12722.2 CDI85110.1 - 3.2 5.3 14.4 3.6 5.1 10.0 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DDHD PF02862.12 CDI85110.1 - 3.5 7.3 13.1 4.7 6.9 9.1 1.2 1 0 0 1 1 1 0 DDHD domain Zip PF02535.17 CDI85110.1 - 3.6 6.5 9.1 4.7 6.1 6.3 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter AUX_IAA PF02309.11 CDI85110.1 - 5.4 6.6 12.7 7.2 6.3 8.8 1.3 1 0 0 1 1 1 0 AUX/IAA family SAGA-Tad1 PF12767.2 CDI85110.1 - 6.2 6.4 22.7 9 5.8 15.7 1.2 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit Paf1 PF03985.8 CDI85110.1 - 6.7 5.3 18.1 8.5 4.9 12.6 1.1 1 0 0 1 1 1 0 Paf1 Presenilin PF01080.12 CDI85110.1 - 6.8 5.4 13.5 8.2 5.1 9.4 1.1 1 0 0 1 1 1 0 Presenilin PAT1 PF09770.4 CDI85110.1 - 7.5 4.6 40.7 8.4 4.4 28.2 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Sec62 PF03839.11 CDI85110.1 - 9.5 5.5 8.9 11 5.2 6.2 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 Cwf_Cwc_15 PF04889.7 CDI85112.1 - 0.028 14.1 5.0 0.039 13.6 3.5 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein SHR3_chaperone PF08229.6 CDI85112.1 - 0.041 12.8 6.3 0.81 8.6 0.0 2.1 2 0 0 2 2 2 0 ER membrane protein SH3 RAB3GAP2_N PF14655.1 CDI85112.1 - 0.041 12.8 9.6 0.045 12.7 6.7 1.2 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus DUF4175 PF13779.1 CDI85112.1 - 0.086 10.5 7.9 0.077 10.6 5.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) GEMIN8 PF15348.1 CDI85112.1 - 0.18 11.8 9.1 0.23 11.4 6.3 1.1 1 0 0 1 1 1 0 Gemini of Cajal bodies-associated protein 8 EphA2_TM PF14575.1 CDI85112.1 - 0.31 11.4 4.0 0.54 10.6 1.1 2.1 2 1 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Zip PF02535.17 CDI85112.1 - 0.34 9.8 3.1 0.4 9.6 2.2 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter CAF-1_p150 PF11600.3 CDI85112.1 - 0.49 9.7 23.1 0.66 9.3 16.0 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DivIC PF04977.10 CDI85112.1 - 0.52 9.8 8.2 0.85 9.1 5.7 1.4 1 0 0 1 1 1 0 Septum formation initiator Hamartin PF04388.7 CDI85112.1 - 0.54 8.8 17.6 0.66 8.5 12.2 1.0 1 0 0 1 1 1 0 Hamartin protein DUF2489 PF10675.4 CDI85112.1 - 0.7 9.5 9.0 0.99 9.0 6.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2489) Peptidase_M56 PF05569.6 CDI85112.1 - 0.76 8.6 4.3 0.84 8.5 3.0 1.1 1 0 0 1 1 1 0 BlaR1 peptidase M56 SOBP PF15279.1 CDI85112.1 - 1.3 9.3 17.9 1.6 9.0 12.4 1.0 1 0 0 1 1 1 0 Sine oculis-binding protein DUF3357 PF11837.3 CDI85112.1 - 2.5 7.9 10.8 14 5.6 3.9 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF3357) Rtf2 PF04641.7 CDI85112.1 - 3 6.9 10.3 4.1 6.5 7.1 1.2 1 0 0 1 1 1 0 Rtf2 RING-finger CD20 PF04103.10 CDI85112.1 - 3.4 7.5 12.9 0.96 9.3 5.4 1.9 1 1 1 2 2 2 0 CD20-like family Suf PF05843.9 CDI85112.1 - 3.6 7.2 16.6 4.2 7.0 11.5 1.0 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF4228 PF14009.1 CDI85112.1 - 7.2 6.6 11.8 8.9 6.4 8.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4228) Sec62 PF03839.11 CDI85112.1 - 7.5 5.8 8.1 9 5.6 5.6 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 DDHD PF02862.12 CDI85112.1 - 8.3 6.1 18.4 11 5.7 12.7 1.1 1 0 0 1 1 1 0 DDHD domain EMG1 PF03587.9 CDI85113.1 - 0.0056 15.9 0.3 0.0056 15.9 0.2 2.9 3 1 0 3 3 3 1 EMG1/NEP1 methyltransferase Nop25 PF09805.4 CDI85113.1 - 3.9 7.5 25.0 0.16 11.9 9.4 3.1 3 0 0 3 3 3 0 Nucleolar protein 12 (25kDa) TPR_1 PF00515.23 CDI85114.1 - 8.6e-09 34.6 1.8 0.00097 18.6 0.1 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat PEX11 PF05648.9 CDI85114.1 - 0.011 15.0 0.9 0.011 15.0 0.6 3.6 2 1 0 2 2 2 0 Peroxisomal biogenesis factor 11 (PEX11) Suf PF05843.9 CDI85114.1 - 0.013 15.2 48.2 0.26 10.9 20.1 2.7 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) CAF-1_p150 PF11600.3 CDI85114.1 - 0.084 12.2 65.3 0.019 14.3 25.6 2.8 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal eIF-3_zeta PF05091.7 CDI85114.1 - 0.11 11.0 38.5 0.64 8.5 16.5 2.3 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Rrn6 PF10214.4 CDI85114.1 - 2.1 6.3 40.8 0.013 13.6 14.0 2.1 2 0 0 2 2 2 0 RNA polymerase I-specific transcription-initiation factor Ndc1_Nup PF09531.5 CDI85114.1 - 8.1 4.7 33.1 3.1 6.1 12.3 2.3 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup DUF4246 PF14033.1 CDI85114.1 - 8.3 4.8 35.8 3.3 6.2 2.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4246) TMEM154 PF15102.1 CDI85115.1 - 0.00036 20.2 5.1 0.00036 20.2 3.5 2.1 2 0 0 2 2 2 1 TMEM154 protein family DOR PF14839.1 CDI85115.1 - 0.025 14.3 1.3 0.04 13.6 0.9 1.2 1 0 0 1 1 1 0 DOR family Adeno_VII PF03228.9 CDI85115.1 - 0.03 14.9 2.7 0.093 13.3 1.8 1.8 2 0 0 2 2 2 0 Adenoviral core protein VII DUF1645 PF07816.6 CDI85115.1 - 0.16 12.4 9.6 0.23 11.9 6.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1645) Peptidase_S64 PF08192.6 CDI85115.1 - 1.7 6.9 4.8 1.8 6.7 3.3 1.1 1 0 0 1 1 1 0 Peptidase family S64 DUF4557 PF15101.1 CDI85117.1 - 6.4 6.5 11.7 9.6 5.9 8.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) CDC37_C PF08564.5 CDI85120.1 - 0.0036 17.1 6.9 0.0042 16.9 4.8 1.1 1 0 0 1 1 1 1 Cdc37 C terminal domain ERF PF04404.7 CDI85120.1 - 0.01 15.3 15.3 0.013 15.0 10.6 1.1 1 0 0 1 1 1 0 ERF superfamily Ribosomal_L19e PF01280.15 CDI85120.1 - 0.057 13.1 8.9 0.06 13.1 6.2 1.0 1 0 0 1 1 1 0 Ribosomal protein L19e FimP PF09766.4 CDI85120.1 - 0.081 11.9 21.2 0.079 12.0 14.7 1.0 1 0 0 1 1 1 0 Fms-interacting protein CRF1 PF10380.4 CDI85120.1 - 0.25 11.6 5.4 0.28 11.5 3.7 1.1 1 0 0 1 1 1 0 Transcription factor CRF1 IPP-2 PF04979.9 CDI85120.1 - 0.89 9.8 9.6 1 9.5 6.6 1.0 1 0 0 1 1 1 0 Protein phosphatase inhibitor 2 (IPP-2) DUF2235 PF09994.4 CDI85120.1 - 1.2 8.3 6.4 1.3 8.2 4.4 1.0 1 0 0 1 1 1 0 Uncharacterized alpha/beta hydrolase domain (DUF2235) CagX PF03524.10 CDI85120.1 - 1.5 8.0 8.9 1.4 8.1 6.2 1.1 1 0 0 1 1 1 0 Conjugal transfer protein Dala_Dala_lig_N PF01820.16 CDI85120.1 - 2.6 8.4 6.1 2.9 8.2 4.2 1.1 1 0 0 1 1 1 0 D-ala D-ala ligase N-terminus DUF4512 PF14975.1 CDI85120.1 - 3 8.7 6.1 3.4 8.5 4.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4512) DUF3408 PF11888.3 CDI85120.1 - 3.2 7.6 12.8 3.6 7.5 8.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) AAT PF03417.11 CDI85120.1 - 3.9 6.8 8.1 4.2 6.7 5.6 1.0 1 0 0 1 1 1 0 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase RIC3 PF15361.1 CDI85120.1 - 3.9 7.6 13.8 4.2 7.5 9.6 1.0 1 0 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 DUF3413 PF11893.3 CDI85120.1 - 3.9 6.2 9.4 5.9 5.7 6.5 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF3413) Peptidase_S49_N PF08496.5 CDI85120.1 - 3.9 7.2 12.3 4.3 7.1 8.5 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DivIC PF04977.10 CDI85120.1 - 3.9 7.0 17.3 5.1 6.6 12.0 1.4 1 0 0 1 1 1 0 Septum formation initiator MSA-2c PF12238.3 CDI85120.1 - 4.1 7.0 9.7 4.4 6.9 6.7 1.0 1 0 0 1 1 1 0 Merozoite surface antigen 2c Suf PF05843.9 CDI85120.1 - 4.1 7.0 16.9 4.2 7.0 11.7 1.0 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Pex14_N PF04695.8 CDI85120.1 - 4.2 7.4 16.3 4.5 7.3 11.3 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Pal1 PF08316.6 CDI85120.1 - 5 7.5 7.0 5.2 7.5 4.8 1.0 1 0 0 1 1 1 0 Pal1 cell morphology protein FLO_LFY PF01698.11 CDI85120.1 - 5 5.8 12.0 5.2 5.8 8.3 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein DUF1764 PF08576.5 CDI85120.1 - 5.8 7.7 16.4 6.6 7.5 11.4 1.1 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) Band_3_cyto PF07565.8 CDI85120.1 - 5.8 6.3 12.8 5.9 6.3 8.9 1.0 1 0 0 1 1 1 0 Band 3 cytoplasmic domain AIF_C PF14721.1 CDI85120.1 - 6 7.1 8.8 6.8 6.9 6.1 1.1 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term DUF4557 PF15101.1 CDI85120.1 - 6.1 6.6 22.7 6.5 6.5 15.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) Serinc PF03348.10 CDI85120.1 - 6.4 5.3 12.1 6.5 5.3 8.4 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) Presenilin PF01080.12 CDI85120.1 - 6.4 5.4 6.0 6.4 5.4 4.2 1.0 1 0 0 1 1 1 0 Presenilin DDHD PF02862.12 CDI85120.1 - 6.7 6.4 10.6 6.8 6.4 7.4 1.0 1 0 0 1 1 1 0 DDHD domain eIF-3_zeta PF05091.7 CDI85120.1 - 6.8 5.1 16.9 7 5.1 11.7 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) zf-DHHC PF01529.15 CDI85120.1 - 7.2 5.9 8.5 7 6.0 5.9 1.1 1 0 0 1 1 1 0 DHHC palmitoyltransferase PAT1 PF09770.4 CDI85120.1 - 7.7 4.6 29.5 7.9 4.5 20.5 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF853 PF05872.7 CDI85120.1 - 8.3 4.6 10.8 8.6 4.5 7.5 1.0 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) DUF605 PF04652.11 CDI85120.1 - 9.3 5.5 17.7 8.9 5.5 12.3 1.0 1 0 0 1 1 1 0 Vta1 like HD-ZIP_N PF04618.7 CDI85120.1 - 9.9 6.7 7.6 12 6.4 5.3 1.1 1 0 0 1 1 1 0 HD-ZIP protein N terminus DUF3333 PF11812.3 CDI85121.1 - 5.2 7.0 17.3 7 6.6 12.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3333) SR-25 PF10500.4 CDI85122.1 - 0.00012 21.6 6.2 0.00012 21.6 4.3 9.0 7 3 2 9 9 9 3 Nuclear RNA-splicing-associated protein DUF2722 PF10846.3 CDI85122.1 - 0.69 8.8 0.0 0.69 8.8 0.0 7.3 4 2 2 7 7 7 0 Protein of unknown function (DUF2722) Na_trans_assoc PF06512.8 CDI85124.1 - 6 6.7 10.3 0.7 9.8 3.4 2.1 2 0 0 2 2 2 0 Sodium ion transport-associated RRM_1 PF00076.17 CDI85125.1 - 1.8e-17 62.7 0.1 3e-17 61.9 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CDI85125.1 - 2.4e-12 46.6 0.0 5e-12 45.6 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CDI85125.1 - 0.00065 19.4 0.0 0.0015 18.3 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SRP_SPB PF02978.14 CDI85125.1 - 0.52 10.5 6.3 0.064 13.5 1.1 1.9 3 0 0 3 3 3 0 Signal peptide binding domain TnpV PF14198.1 CDI85125.1 - 7.6 6.4 8.6 13 5.7 2.2 3.0 3 0 0 3 3 3 0 Transposon-encoded protein TnpV DUF4045 PF13254.1 CDI85129.1 - 0.0092 15.3 12.5 0.01 15.1 8.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4045) SprA-related PF12118.3 CDI85129.1 - 0.013 14.8 35.9 0.02 14.2 24.9 1.4 1 0 0 1 1 1 0 SprA-related family DUF1777 PF08648.7 CDI85129.1 - 0.014 15.1 10.8 0.017 14.8 7.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) FLO_LFY PF01698.11 CDI85129.1 - 0.046 12.5 15.9 0.058 12.2 11.0 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein SAGA-Tad1 PF12767.2 CDI85129.1 - 0.091 12.4 19.7 0.13 11.9 13.7 1.2 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit Ycf1 PF05758.7 CDI85129.1 - 0.18 9.5 12.9 0.2 9.3 8.9 1.2 1 0 0 1 1 1 0 Ycf1 SOBP PF15279.1 CDI85129.1 - 0.19 12.0 11.8 0.24 11.7 8.1 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein SAPS PF04499.10 CDI85129.1 - 0.43 9.1 12.1 0.44 9.1 8.4 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Hid1 PF12722.2 CDI85129.1 - 0.45 8.1 14.9 0.5 7.9 10.4 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF4647 PF15504.1 CDI85129.1 - 0.54 9.0 21.7 0.66 8.7 15.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4647) Raftlin PF15250.1 CDI85129.1 - 0.59 8.5 14.8 0.79 8.1 10.2 1.1 1 0 0 1 1 1 0 Raftlin FAM60A PF15396.1 CDI85129.1 - 0.76 9.4 14.7 0.92 9.2 10.2 1.2 1 0 0 1 1 1 0 Protein Family FAM60A GAGA_bind PF06217.7 CDI85129.1 - 0.93 9.3 16.5 1.2 9.0 11.4 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family SPX PF03105.14 CDI85129.1 - 0.99 9.1 15.4 1.3 8.7 10.6 1.2 1 0 0 1 1 1 0 SPX domain DUF2946 PF11162.3 CDI85129.1 - 1.1 9.4 6.3 0.25 11.5 1.8 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2946) CTNNB1_binding PF08347.6 CDI85129.1 - 1.3 9.2 12.1 0.99 9.6 7.5 1.5 1 1 1 2 2 2 0 N-terminal CTNNB1 binding DUF913 PF06025.7 CDI85129.1 - 2.5 6.7 8.7 3.6 6.2 6.0 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) SID-1_RNA_chan PF13965.1 CDI85129.1 - 2.9 5.9 6.2 3.5 5.6 4.3 1.3 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Asp-B-Hydro_N PF05279.6 CDI85129.1 - 3 7.6 16.4 3.9 7.2 11.3 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Cellulose_synt PF03552.9 CDI85129.1 - 3.9 5.6 5.3 4.4 5.4 3.7 1.2 1 0 0 1 1 1 0 Cellulose synthase Zip PF02535.17 CDI85129.1 - 5.4 5.9 6.0 6.7 5.6 4.2 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Herpes_UL25 PF01499.11 CDI85129.1 - 5.7 5.1 20.3 9.5 4.3 14.1 1.3 1 0 0 1 1 1 0 Herpesvirus UL25 family Neur_chan_memb PF02932.11 CDI85129.1 - 6 6.6 12.0 7.1 6.4 8.3 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF2126 PF09899.4 CDI85129.1 - 8.4 4.2 13.0 9.7 4.0 9.0 1.1 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) SR-25 PF10500.4 CDI85130.1 - 0.0045 16.4 20.3 0.0045 16.4 14.1 4.2 4 1 0 4 4 4 1 Nuclear RNA-splicing-associated protein SGT1 PF07093.6 CDI85130.1 - 0.92 7.8 50.8 0.38 9.0 5.8 2.1 2 0 0 2 2 2 0 SGT1 protein DUF533 PF04391.7 CDI85131.1 - 0.00023 20.6 1.8 0.00027 20.3 1.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF533) Gly-zipper_OmpA PF13436.1 CDI85131.1 - 0.0019 17.8 3.0 0.0026 17.4 2.1 1.2 1 0 0 1 1 1 1 Glycine-zipper containing OmpA-like membrane domain FHIPEP PF00771.15 CDI85131.1 - 0.02 13.2 0.0 0.024 12.9 0.0 1.1 1 0 0 1 1 1 0 FHIPEP family Ribosomal_60s PF00428.14 CDI85131.1 - 0.029 14.7 0.2 0.04 14.3 0.1 1.2 1 0 0 1 1 1 0 60s Acidic ribosomal protein Suf PF05843.9 CDI85131.1 - 0.048 13.3 0.5 0.052 13.2 0.3 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) RskA PF10099.4 CDI85131.1 - 0.083 12.6 4.2 0.14 11.8 2.9 1.3 1 0 0 1 1 1 0 Anti-sigma-K factor rskA DUF2422 PF10337.4 CDI85131.1 - 0.099 11.4 0.7 0.13 11.0 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2422) Zip PF02535.17 CDI85131.1 - 0.11 11.4 0.0 0.11 11.4 0.0 1.5 2 0 0 2 2 2 0 ZIP Zinc transporter Activator_LAG-3 PF11498.3 CDI85131.1 - 0.24 10.1 16.0 0.3 9.7 11.1 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 JHBP PF06585.6 CDI85131.1 - 0.6 8.8 1.9 10 4.8 0.3 2.0 2 0 0 2 2 2 0 Haemolymph juvenile hormone binding protein (JHBP) Med15 PF09606.5 CDI85131.1 - 1 7.4 16.4 1.3 7.1 11.4 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal PepSY_2 PF13670.1 CDI85131.1 - 1.3 9.0 8.2 2.4 8.0 5.7 1.4 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain Rick_17kDa_Anti PF05433.10 CDI85131.1 - 2.8 7.6 10.2 3.9 7.2 7.1 1.2 1 0 0 1 1 1 0 Glycine zipper 2TM domain GRP PF07172.6 CDI85131.1 - 5.1 7.6 5.3 6.3 7.3 0.1 2.2 2 0 0 2 2 2 0 Glycine rich protein family IF-2B PF01008.12 CDI85134.1 - 0.00024 20.1 0.5 0.00044 19.3 0.0 1.7 2 0 0 2 2 2 1 Initiation factor 2 subunit family Dehydrin PF00257.14 CDI85134.1 - 0.0018 18.6 13.0 0.0018 18.6 9.0 2.0 1 1 1 2 2 2 1 Dehydrin Sec62 PF03839.11 CDI85134.1 - 0.014 14.8 1.6 0.019 14.4 1.1 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 DUF4045 PF13254.1 CDI85134.1 - 0.041 13.1 6.9 0.064 12.5 4.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Pyr_redox_2 PF07992.9 CDI85134.1 - 0.043 13.6 1.0 0.063 13.1 0.7 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Glt_symporter PF03616.9 CDI85134.1 - 0.16 10.4 3.2 0.27 9.6 2.2 1.3 1 0 0 1 1 1 0 Sodium/glutamate symporter RskA PF10099.4 CDI85134.1 - 0.19 11.4 9.8 0.34 10.6 6.8 1.4 1 1 0 1 1 1 0 Anti-sigma-K factor rskA HemX PF04375.9 CDI85134.1 - 0.24 9.9 15.1 0.36 9.3 10.4 1.2 1 0 0 1 1 1 0 HemX TFIIA PF03153.8 CDI85134.1 - 0.42 10.4 21.0 0.57 10.0 14.6 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Med15 PF09606.5 CDI85134.1 - 0.68 8.0 35.4 0.91 7.6 24.5 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF572 PF04502.8 CDI85134.1 - 0.75 8.9 8.8 1 8.5 6.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Peroxin-13_N PF04088.8 CDI85134.1 - 1.5 8.7 5.5 42 4.0 0.0 2.8 1 1 2 3 3 3 0 Peroxin 13, N-terminal region Spore_YhcN_YlaJ PF09580.5 CDI85134.1 - 3 7.9 13.6 7.9 6.5 6.0 2.1 2 0 0 2 2 2 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) DcuC PF03606.10 CDI85134.1 - 5.2 5.1 8.1 1.3 7.1 0.1 2.1 1 1 1 2 2 2 0 C4-dicarboxylate anaerobic carrier PAT1 PF09770.4 CDI85134.1 - 5.2 5.1 34.3 6.8 4.7 23.8 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF912 PF06024.7 CDI85134.1 - 9.5 6.3 16.4 1.3 9.1 0.5 2.9 1 1 2 3 3 3 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF1645 PF07816.6 CDI85134.1 - 9.8 6.5 10.8 18 5.7 5.9 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1645) DUF615 PF04751.9 CDI85135.1 - 0.0013 18.4 1.4 0.0016 18.0 1.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF615) MMS22L_C PF14911.1 CDI85135.1 - 0.031 13.3 0.0 0.04 12.9 0.0 1.1 1 0 0 1 1 1 0 S-phase genomic integrity recombination mediator, C-terminal VPR PF00522.13 CDI85135.1 - 0.085 12.6 0.1 0.16 11.7 0.1 1.4 1 0 0 1 1 1 0 VPR/VPX protein DUF2990 PF11693.3 CDI85135.1 - 0.13 12.0 0.1 2.8 7.8 0.1 2.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2990) Peptidase_C6 PF00851.13 CDI85135.1 - 0.24 9.9 1.9 0.31 9.6 1.3 1.1 1 0 0 1 1 1 0 Helper component proteinase CTK3 PF12243.3 CDI85136.1 - 0.12 11.9 0.0 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 CTD kinase subunit gamma CTK3 DUF1470 PF07336.6 CDI85136.1 - 2.8 8.2 7.5 0.072 13.4 0.7 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1470) UCH PF00443.24 CDI85137.1 - 1.1e-17 63.9 0.0 1.4e-17 63.6 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.18 CDI85137.1 - 6.8e-05 22.1 0.0 0.00013 21.3 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family UCH_1 PF13423.1 CDI85137.1 - 0.00089 18.7 0.0 0.0013 18.2 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Ubiquitin_2 PF14560.1 CDI85137.1 - 0.14 12.4 0.0 1.3 9.3 0.0 2.1 2 0 0 2 2 2 0 Ubiquitin-like domain Fasciclin PF02469.17 CDI85138.1 - 0.0012 18.8 0.0 0.0026 17.7 0.0 1.5 1 0 0 1 1 1 1 Fasciclin domain Macoilin PF09726.4 CDI85139.1 - 0.11 10.7 34.9 0.27 9.4 11.9 2.2 2 0 0 2 2 2 0 Transmembrane protein SOBP PF15279.1 CDI85139.1 - 2 8.7 19.8 1.6 9.0 1.3 2.3 2 0 0 2 2 2 0 Sine oculis-binding protein zf-C4H2 PF10146.4 CDI85140.1 - 0.14 12.1 3.0 0.19 11.7 2.1 1.2 1 0 0 1 1 1 0 Zinc finger-containing protein RskA PF10099.4 CDI85140.1 - 0.17 11.6 13.7 0.21 11.3 9.5 1.1 1 0 0 1 1 1 0 Anti-sigma-K factor rskA MSP1_C PF07462.6 CDI85140.1 - 0.8 8.0 14.8 0.97 7.7 10.2 1.1 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus PIN_3 PF13470.1 CDI85140.1 - 2.1 9.0 9.7 3.2 8.4 6.7 1.3 1 0 0 1 1 1 0 PIN domain DUF4349 PF14257.1 CDI85140.1 - 4.5 6.4 16.5 5.9 6.0 11.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) Tetraspannin PF00335.15 CDI85141.1 - 0.44 9.7 10.4 1.2 8.4 0.0 2.5 2 0 0 2 2 2 0 Tetraspanin family OAD_gamma PF04277.8 CDI85141.1 - 1 9.7 13.9 1.9 8.9 0.6 3.5 3 0 0 3 3 3 0 Oxaloacetate decarboxylase, gamma chain DDHD PF02862.12 CDI85141.1 - 2 8.1 26.5 0.79 9.4 1.9 2.2 2 0 0 2 2 2 0 DDHD domain SOBP PF15279.1 CDI85141.1 - 2 8.7 23.1 2.4 8.4 7.8 2.3 2 0 0 2 2 2 0 Sine oculis-binding protein Apt1 PF10351.4 CDI85141.1 - 2.4 6.9 31.2 0.31 9.8 1.9 2.2 2 0 0 2 2 2 0 Golgi-body localisation protein domain DUF966 PF06136.8 CDI85141.1 - 3.9 6.7 31.1 3.2 7.0 5.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF966) DHHW PF14286.1 CDI85141.1 - 5.2 6.2 14.8 1.3 8.2 4.7 2.2 2 0 0 2 2 2 0 DHHW protein SpoVR PF04293.8 CDI85143.1 - 0.001 17.5 2.5 0.001 17.5 1.7 3.0 2 1 0 3 3 2 1 SpoVR like protein DDHD PF02862.12 CDI85143.1 - 0.017 14.8 20.7 0.098 12.4 7.1 2.2 2 0 0 2 2 2 0 DDHD domain zf-DHHC PF01529.15 CDI85143.1 - 0.15 11.4 14.4 2.9 7.2 0.3 3.2 3 0 0 3 3 3 0 DHHC palmitoyltransferase Eapp_C PF10238.4 CDI85143.1 - 0.19 11.5 18.1 3 7.7 1.1 3.2 3 0 0 3 3 3 0 E2F-associated phosphoprotein Peptidase_S41 PF03572.13 CDI85143.1 - 0.24 10.7 0.1 0.24 10.7 0.1 2.6 2 1 0 2 2 2 0 Peptidase family S41 Rtf2 PF04641.7 CDI85143.1 - 0.68 9.0 24.9 0.85 8.7 2.3 2.2 2 0 0 2 2 2 0 Rtf2 RING-finger DUF4366 PF14283.1 CDI85143.1 - 0.7 9.2 18.1 1.3 8.4 6.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4366) TFIIF_alpha PF05793.7 CDI85143.1 - 1.3 7.3 18.9 0.38 9.0 9.6 1.9 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Mu-like_Pro PF10123.4 CDI85143.1 - 1.6 8.0 32.0 0.27 10.6 10.0 2.1 2 0 0 2 2 2 0 Mu-like prophage I protein FLO_LFY PF01698.11 CDI85143.1 - 1.8 7.3 22.9 2.2 7.0 1.2 2.3 2 0 0 2 2 2 0 Floricaula / Leafy protein Nha1_C PF08619.5 CDI85143.1 - 2.3 7.3 25.0 1.5 7.9 7.9 2.1 2 0 0 2 2 2 0 Alkali metal cation/H+ antiporter Nha1 C terminus DUF1840 PF08895.6 CDI85143.1 - 3.1 7.8 29.0 4.7 7.2 3.1 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF1840) Hid1 PF12722.2 CDI85143.1 - 3.1 5.3 24.7 0.34 8.5 1.7 2.1 2 0 0 2 2 2 0 High-temperature-induced dauer-formation protein FCP1_C PF09309.5 CDI85143.1 - 3.2 7.0 34.9 1.9 7.7 3.2 3.3 3 0 0 3 3 3 0 FCP1, C-terminal Pap_E4 PF02711.9 CDI85143.1 - 3.6 8.4 17.4 1.2 9.9 0.8 3.3 3 0 0 3 3 3 0 E4 protein Rrp15p PF07890.7 CDI85143.1 - 4.6 7.3 27.9 5.9 6.9 3.3 3.3 3 0 0 3 3 3 0 Rrp15p ERF PF04404.7 CDI85143.1 - 5 6.6 44.8 1.8 8.0 6.6 3.3 3 0 0 3 3 3 0 ERF superfamily BORG_CEP PF14957.1 CDI85143.1 - 6.7 7.6 17.9 12 6.8 0.4 3.2 3 0 0 3 3 3 0 Cdc42 effector DUF2722 PF10846.3 CDI85143.1 - 7.7 5.4 34.4 0.16 10.9 3.6 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2722) Presenilin PF01080.12 CDI85143.1 - 8.7 5.0 16.3 6.8 5.4 5.3 2.3 2 0 0 2 2 2 0 Presenilin Herpes_UL87 PF03043.9 CDI85143.1 - 9.3 4.5 13.2 29 2.8 9.1 1.8 1 1 0 1 1 1 0 Herpesvirus UL87 family DUF4512 PF14975.1 CDI85143.1 - 9.9 7.0 17.4 8.9 7.2 1.1 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4512) DUF4199 PF13858.1 CDI85144.1 - 0.00032 20.6 0.0 0.00033 20.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4199) Med3 PF11593.3 CDI85144.1 - 0.02 14.1 6.4 0.023 13.9 4.5 1.0 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal XPG_N PF00752.12 CDI85144.1 - 0.038 14.2 0.0 0.048 13.9 0.0 1.1 1 0 0 1 1 1 0 XPG N-terminal domain DUF1977 PF09320.6 CDI85144.1 - 0.06 13.5 2.0 0.071 13.3 1.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1977) FAM222A PF15258.1 CDI85144.1 - 0.065 12.4 3.8 0.074 12.2 2.6 1.0 1 0 0 1 1 1 0 Protein family of FAM222A FixH PF05751.6 CDI85144.1 - 0.07 12.9 0.0 0.072 12.9 0.0 1.0 1 0 0 1 1 1 0 FixH zf-DHHC PF01529.15 CDI85144.1 - 0.13 11.6 0.8 0.14 11.5 0.6 1.1 1 0 0 1 1 1 0 DHHC palmitoyltransferase DUF533 PF04391.7 CDI85144.1 - 0.23 10.7 3.7 0.3 10.4 2.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF533) TSA PF03249.8 CDI85144.1 - 0.58 8.6 10.7 0.6 8.5 7.4 1.0 1 0 0 1 1 1 0 Type specific antigen Phostensin_N PF13916.1 CDI85144.1 - 0.83 9.6 8.4 1.1 9.3 5.8 1.1 1 0 0 1 1 1 0 PP1-regulatory protein, Phostensin N-terminal CcmD PF04995.9 CDI85144.1 - 1.3 8.8 4.0 2.3 8.0 2.8 1.5 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) PHD_3 PF13922.1 CDI85144.1 - 3.9 7.7 6.8 5.5 7.3 4.7 1.2 1 0 0 1 1 1 0 PHD domain of transcriptional enhancer, Asx Androgen_recep PF02166.11 CDI85144.1 - 5.1 5.8 5.9 5.8 5.6 4.1 1.0 1 0 0 1 1 1 0 Androgen receptor Pal1 PF08316.6 CDI85145.1 - 0.26 11.7 17.0 0.39 11.1 3.2 2.1 1 1 1 2 2 2 0 Pal1 cell morphology protein CAF-1_p150 PF11600.3 CDI85145.1 - 0.42 9.9 36.8 0.54 9.6 25.5 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF1212 PF06738.7 CDI85146.1 - 0.067 12.6 0.3 0.067 12.6 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1212) Ribosomal_60s PF00428.14 CDI85146.1 - 0.63 10.4 30.2 0.34 11.3 1.4 3.9 3 1 0 3 3 3 0 60s Acidic ribosomal protein Pox_Ag35 PF03286.9 CDI85146.1 - 3.8 6.9 14.2 7.9 5.9 9.6 1.7 1 1 0 1 1 1 0 Pox virus Ag35 surface protein Peptidase_S64 PF08192.6 CDI85146.1 - 8.7 4.5 20.9 12 4.1 14.5 1.1 1 0 0 1 1 1 0 Peptidase family S64 DnaJ-X PF14308.1 CDI85147.1 - 0.00096 18.4 1.9 0.0023 17.2 1.3 1.7 1 0 0 1 1 1 1 X-domain of DnaJ-containing SseC PF04888.7 CDI85147.1 - 0.0053 16.1 22.6 0.0053 16.1 15.6 2.4 2 0 0 2 2 1 1 Secretion system effector C (SseC) like family Ycf1 PF05758.7 CDI85147.1 - 0.04 11.6 3.0 0.045 11.4 2.1 1.1 1 0 0 1 1 1 0 Ycf1 HCO3_cotransp PF00955.16 CDI85147.1 - 0.049 12.3 0.3 0.068 11.8 0.2 1.2 1 0 0 1 1 1 0 HCO3- transporter family Hid1 PF12722.2 CDI85147.1 - 0.099 10.3 6.8 0.12 10.0 4.7 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein PBP1_TM PF14812.1 CDI85147.1 - 0.12 12.7 1.5 0.81 10.0 0.6 2.1 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal PAT1 PF09770.4 CDI85147.1 - 0.33 9.1 31.3 0.49 8.5 21.7 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Glyco_transf_10 PF00852.14 CDI85147.1 - 0.37 9.3 5.9 0.53 8.8 4.1 1.1 1 0 0 1 1 1 0 Glycosyltransferase family 10 (fucosyltransferase) YjgP_YjgQ PF03739.9 CDI85147.1 - 0.62 8.7 4.5 5.4 5.6 0.6 2.3 2 0 0 2 2 2 0 Predicted permease YjgP/YjgQ family DUF4407 PF14362.1 CDI85147.1 - 0.85 8.5 23.0 0.071 12.0 4.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) G0-G1_switch_2 PF15103.1 CDI85147.1 - 0.86 9.8 14.3 2.4 8.4 0.2 2.4 2 0 0 2 2 2 0 G0/G1 switch protein 2 Glyco_transf_15 PF01793.11 CDI85147.1 - 1.1 8.1 6.3 1.8 7.4 4.3 1.3 1 0 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase RR_TM4-6 PF06459.7 CDI85147.1 - 1.8 8.4 11.5 0.24 11.2 4.9 1.7 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 FimP PF09766.4 CDI85147.1 - 1.8 7.5 25.9 0.2 10.6 13.5 1.9 2 0 0 2 2 2 0 Fms-interacting protein Tim54 PF11711.3 CDI85147.1 - 3.2 6.2 14.2 21 3.5 9.9 1.9 1 1 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 MRI PF15325.1 CDI85147.1 - 4.8 8.2 12.2 0.24 12.4 2.8 2.5 2 0 0 2 2 2 0 Modulator of retrovirus infection DUF912 PF06024.7 CDI85147.1 - 6.5 6.8 10.7 1.3 9.1 4.7 1.8 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) OATP PF03137.15 CDI85147.1 - 6.7 4.6 14.6 0.092 10.7 2.7 2.5 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family DUF1980 PF09323.5 CDI85147.1 - 7 6.3 6.5 18 5.0 4.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) WES_acyltransf PF03007.11 CDI85147.1 - 9.7 5.6 18.1 2.6 7.5 3.8 2.6 2 1 1 3 3 3 0 Wax ester synthase-like Acyl-CoA acyltransferase domain MIP-T3 PF10243.4 CDI85148.1 - 2 6.8 73.6 2.4 6.5 51.1 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 SprA-related PF12118.3 CDI85149.1 - 1.7 7.9 47.1 2 7.6 32.6 1.0 1 0 0 1 1 1 0 SprA-related family Activator_LAG-3 PF11498.3 CDI85153.1 - 4.4e-08 32.3 47.6 1.1e-07 30.9 27.4 2.3 2 0 0 2 2 2 2 Transcriptional activator LAG-3 Raftlin PF15250.1 CDI85153.1 - 3 6.2 23.8 0.14 10.6 11.5 2.1 2 0 0 2 2 2 0 Raftlin Med15 PF09606.5 CDI85156.1 - 0.0018 16.6 23.3 0.0023 16.2 16.1 1.2 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal SseC PF04888.7 CDI85156.1 - 0.002 17.5 18.3 0.0027 17.0 12.7 1.2 1 0 0 1 1 1 1 Secretion system effector C (SseC) like family Spt20 PF12090.3 CDI85156.1 - 0.0023 17.3 8.0 0.0024 17.2 5.6 1.1 1 0 0 1 1 1 1 Spt20 family Chloroplast_duf PF14476.1 CDI85156.1 - 0.0025 16.6 3.3 0.0031 16.3 2.3 1.1 1 0 0 1 1 1 1 Petal formation-expressed Tom22 PF04281.8 CDI85156.1 - 0.0052 16.3 2.9 0.0068 15.9 2.0 1.2 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom22 BAF1_ABF1 PF04684.8 CDI85156.1 - 0.0084 15.0 34.5 0.018 13.9 23.9 1.4 1 1 0 1 1 1 1 BAF1 / ABF1 chromatin reorganising factor Pex14_N PF04695.8 CDI85156.1 - 0.013 15.5 8.0 0.019 15.0 5.6 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region MMPL PF03176.10 CDI85156.1 - 0.015 14.0 8.4 0.017 13.8 5.8 1.0 1 0 0 1 1 1 0 MMPL family DUF4175 PF13779.1 CDI85156.1 - 0.017 12.8 27.5 0.024 12.3 19.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) OSTbeta PF15048.1 CDI85156.1 - 0.034 14.2 6.5 0.043 13.8 4.5 1.2 1 0 0 1 1 1 0 Organic solute transporter subunit beta protein Pex16 PF08610.5 CDI85156.1 - 0.039 12.9 3.1 0.04 12.9 2.2 1.0 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) DUF966 PF06136.8 CDI85156.1 - 0.04 13.3 4.8 0.046 13.1 3.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF966) PAT1 PF09770.4 CDI85156.1 - 0.042 12.0 16.1 0.043 12.0 11.2 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TMEM51 PF15345.1 CDI85156.1 - 0.056 13.1 8.8 0.07 12.8 6.1 1.1 1 0 0 1 1 1 0 Transmembrane protein 51 DUF1777 PF08648.7 CDI85156.1 - 0.061 13.0 3.0 0.076 12.7 2.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) DivIC PF04977.10 CDI85156.1 - 0.068 12.6 16.3 0.12 11.8 11.3 1.5 1 0 0 1 1 1 0 Septum formation initiator DUF4045 PF13254.1 CDI85156.1 - 0.071 12.3 5.8 0.08 12.2 4.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) DUF1943 PF09172.6 CDI85156.1 - 0.071 11.9 2.6 0.07 11.9 1.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1943) Hid1 PF12722.2 CDI85156.1 - 0.1 10.2 5.8 0.099 10.3 4.0 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF4616 PF15394.1 CDI85156.1 - 0.11 11.5 6.9 0.12 11.4 4.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4616) FAM176 PF14851.1 CDI85156.1 - 0.11 12.1 2.5 0.14 11.8 1.7 1.2 1 0 0 1 1 1 0 FAM176 family HlyD_2 PF12700.2 CDI85156.1 - 0.14 11.3 7.2 0.16 11.1 5.0 1.1 1 0 0 1 1 1 0 HlyD family secretion protein Tfb4 PF03850.9 CDI85156.1 - 0.16 11.1 5.1 0.19 10.9 3.6 1.1 1 0 0 1 1 1 0 Transcription factor Tfb4 Gti1_Pac2 PF09729.4 CDI85156.1 - 0.19 11.5 3.2 0.21 11.4 2.2 1.1 1 0 0 1 1 1 0 Gti1/Pac2 family Band_3_cyto PF07565.8 CDI85156.1 - 0.2 11.1 7.6 0.23 10.9 5.3 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Herpes_env PF01673.13 CDI85156.1 - 0.21 10.1 8.5 0.24 9.9 5.9 1.0 1 0 0 1 1 1 0 Herpesvirus putative major envelope glycoprotein Ribosomal_60s PF00428.14 CDI85156.1 - 0.24 11.8 14.0 0.42 11.0 9.7 1.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein Peptidase_S64 PF08192.6 CDI85156.1 - 0.26 9.6 4.7 0.28 9.4 3.3 1.0 1 0 0 1 1 1 0 Peptidase family S64 DUF3371 PF11851.3 CDI85156.1 - 0.33 11.6 12.9 0.44 11.2 8.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3371) Mem_trans PF03547.13 CDI85156.1 - 0.36 9.0 1.7 0.4 8.9 1.2 1.1 1 0 0 1 1 1 0 Membrane transport protein Asp-B-Hydro_N PF05279.6 CDI85156.1 - 0.37 10.5 7.9 0.45 10.3 5.4 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Herpes_DNAp_acc PF04929.7 CDI85156.1 - 0.46 9.4 6.0 0.58 9.0 4.2 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor FHIPEP PF00771.15 CDI85156.1 - 0.57 8.4 5.8 0.63 8.3 4.0 1.2 1 0 0 1 1 1 0 FHIPEP family FimP PF09766.4 CDI85156.1 - 0.61 9.1 17.1 0.77 8.7 11.9 1.2 1 0 0 1 1 1 0 Fms-interacting protein Ycf1 PF05758.7 CDI85156.1 - 0.64 7.6 7.5 0.63 7.6 5.2 1.0 1 0 0 1 1 1 0 Ycf1 Neur_chan_memb PF02932.11 CDI85156.1 - 0.73 9.6 2.8 0.75 9.6 1.9 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Folate_carrier PF01770.13 CDI85156.1 - 0.86 8.0 3.5 1 7.8 2.4 1.2 1 0 0 1 1 1 0 Reduced folate carrier DDHD PF02862.12 CDI85156.1 - 0.89 9.3 6.7 1.1 8.9 4.6 1.1 1 0 0 1 1 1 0 DDHD domain UPF0560 PF10577.4 CDI85156.1 - 1.1 7.4 10.2 1.2 7.2 7.1 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 ATAD4 PF15321.1 CDI85156.1 - 1.7 9.6 8.5 2.7 9.0 5.9 1.3 1 0 0 1 1 1 0 ATPase family AAA domain containing 4 Endonuc_Holl PF10107.4 CDI85156.1 - 1.7 8.3 12.0 2.4 7.8 8.3 1.1 1 0 0 1 1 1 0 Endonuclease related to archaeal Holliday junction resolvase Androgen_recep PF02166.11 CDI85156.1 - 1.9 7.2 13.9 2.2 7.0 9.6 1.1 1 0 0 1 1 1 0 Androgen receptor DUF1266 PF06889.6 CDI85156.1 - 2.1 8.1 11.8 2.5 7.8 8.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1266) Glyco_transf_15 PF01793.11 CDI85156.1 - 2.7 6.8 9.4 3.1 6.6 6.5 1.1 1 0 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase RED_N PF07808.8 CDI85156.1 - 2.8 7.0 15.6 3.8 6.6 10.8 1.2 1 0 0 1 1 1 0 RED-like protein N-terminal region Conotoxin PF02950.12 CDI85156.1 - 3 8.6 13.7 0.11 13.2 3.9 2.2 2 1 0 2 2 2 0 Conotoxin Sporozoite_P67 PF05642.6 CDI85156.1 - 3.6 5.3 5.2 5.3 4.7 3.6 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF3533 PF12051.3 CDI85156.1 - 4.1 6.0 5.7 4.8 5.8 4.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3533) Paramyxo_ncap PF00973.14 CDI85156.1 - 4.2 5.9 8.8 5.1 5.6 6.1 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein DUF3316 PF11777.3 CDI85156.1 - 4.4 7.1 7.2 0.49 10.1 1.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3316) FAM222A PF15258.1 CDI85156.1 - 5.4 6.1 15.7 6.8 5.7 10.9 1.2 1 0 0 1 1 1 0 Protein family of FAM222A Rota_VP2 PF05087.7 CDI85156.1 - 6.2 4.6 8.8 7.1 4.4 6.1 1.0 1 0 0 1 1 1 0 Rotavirus VP2 protein AIF-MLS PF14962.1 CDI85156.1 - 6.3 6.4 12.2 8.1 6.0 8.4 1.1 1 0 0 1 1 1 0 Mitochondria Localisation Sequence PLRV_ORF5 PF01690.12 CDI85157.1 - 0.39 9.7 13.3 0.57 9.2 9.2 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein DUF2116 PF09889.4 CDI85157.1 - 2 8.2 5.2 3.6 7.4 3.6 1.3 1 0 0 1 1 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) DnaJ PF00226.26 CDI85158.1 - 2.8e-11 42.9 0.0 7.7e-11 41.5 0.0 1.7 1 0 0 1 1 1 1 DnaJ domain Glycos_transf_2 PF00535.21 CDI85159.1 - 1.3e-21 76.9 0.0 2.6e-21 76.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 Ricin_B_lectin PF00652.17 CDI85159.1 - 7.1e-11 42.2 0.0 1.3e-10 41.3 0.0 1.3 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glyco_tranf_2_2 PF10111.4 CDI85159.1 - 3e-08 33.0 0.0 5.4e-08 32.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_3 PF13641.1 CDI85159.1 - 4.1e-08 33.3 0.0 6.1e-08 32.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_7C PF02709.9 CDI85159.1 - 4.9e-08 32.3 0.6 4.7e-07 29.1 0.1 2.3 2 0 0 2 2 2 1 N-terminal domain of galactosyltransferase RicinB_lectin_2 PF14200.1 CDI85159.1 - 0.051 13.9 0.0 0.11 12.8 0.0 1.6 1 1 0 1 1 1 0 Ricin-type beta-trefoil lectin domain-like GlcNAc PF11397.3 CDI85159.1 - 0.1 11.6 0.5 0.29 10.2 0.4 1.6 1 1 0 1 1 1 0 Glycosyltransferase (GlcNAc) Spt20 PF12090.3 CDI85162.1 - 0.0036 16.6 0.7 0.0036 16.6 0.5 1.2 1 0 0 1 1 1 1 Spt20 family FimP PF09766.4 CDI85162.1 - 0.058 12.4 5.9 0.076 12.0 4.1 1.1 1 0 0 1 1 1 0 Fms-interacting protein PAT1 PF09770.4 CDI85162.1 - 0.24 9.5 36.1 0.29 9.3 25.0 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 PAXIP1_C PF15364.1 CDI85162.1 - 0.38 10.6 6.6 0.6 10.0 4.5 1.2 1 0 0 1 1 1 0 PAXIP1-associated-protein-1 C term PTIP binding protein Mito_fiss_reg PF05308.6 CDI85162.1 - 2.1 7.6 38.3 2.6 7.3 13.0 2.1 1 1 1 2 2 2 0 Mitochondrial fission regulator YqfQ PF14181.1 CDI85164.1 - 0.19 11.7 23.8 0.21 11.6 16.5 1.0 1 0 0 1 1 1 0 YqfQ-like protein G-alpha PF00503.15 CDI85164.1 - 0.73 8.4 20.2 0.75 8.4 14.0 1.0 1 0 0 1 1 1 0 G-protein alpha subunit DUF1510 PF07423.6 CDI85164.1 - 0.93 8.8 27.1 1 8.6 18.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DUF2457 PF10446.4 CDI85164.1 - 1.8 7.1 16.6 1.9 7.1 11.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DDRGK PF09756.4 CDI85164.1 - 2.5 7.4 35.4 2.9 7.2 24.6 1.0 1 0 0 1 1 1 0 DDRGK domain TRAP_alpha PF03896.11 CDI85164.1 - 3 6.7 15.5 3.2 6.6 10.7 1.0 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Gti1_Pac2 PF09729.4 CDI85164.1 - 3.2 7.5 15.8 3.5 7.4 11.0 1.1 1 0 0 1 1 1 0 Gti1/Pac2 family RNA_pol_Rpc4 PF05132.9 CDI85164.1 - 3.3 7.7 17.4 4.6 7.2 12.1 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 DDHD PF02862.12 CDI85164.1 - 3.3 7.4 20.2 3.9 7.2 14.0 1.0 1 0 0 1 1 1 0 DDHD domain DUF2370 PF10176.4 CDI85164.1 - 3.8 6.7 13.3 4.2 6.6 9.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) DUF1764 PF08576.5 CDI85164.1 - 4.1 8.2 20.8 6 7.6 14.4 1.2 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) CENP-T PF15511.1 CDI85164.1 - 4.1 6.5 20.3 4.5 6.4 14.1 1.0 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T FYDLN_acid PF09538.5 CDI85164.1 - 4.2 7.9 16.7 5.6 7.6 11.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) Zip PF02535.17 CDI85164.1 - 4.2 6.2 17.2 4.5 6.1 11.9 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter Vfa1 PF08432.5 CDI85164.1 - 5.5 6.9 22.6 6.4 6.7 15.7 1.0 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF3449 PF11931.3 CDI85164.1 - 5.9 6.3 21.8 6.5 6.2 15.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3449) Tfb4 PF03850.9 CDI85164.1 - 6.1 6.0 13.3 6.2 5.9 9.2 1.0 1 0 0 1 1 1 0 Transcription factor Tfb4 DUF3408 PF11888.3 CDI85164.1 - 7.1 6.5 17.7 11 5.9 12.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) SpoIIIAH PF12685.2 CDI85164.1 - 7.2 6.0 19.1 7.9 5.9 13.2 1.0 1 0 0 1 1 1 0 SpoIIIAH-like protein Pox_Ag35 PF03286.9 CDI85164.1 - 7.9 5.9 19.3 9.9 5.6 13.4 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein NPR3 PF03666.8 CDI85164.1 - 8.2 4.8 19.1 9.3 4.6 13.2 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Nop14 PF04147.7 CDI85164.1 - 8.7 4.1 23.2 10 3.8 16.1 1.0 1 0 0 1 1 1 0 Nop14-like family DUF2052 PF09747.4 CDI85164.1 - 8.8 6.2 30.6 9.8 6.0 21.2 1.0 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) Dehydrin PF00257.14 CDI85166.1 - 0.029 14.7 3.6 0.039 14.2 2.5 1.2 1 0 0 1 1 1 0 Dehydrin DNA_pol_phi PF04931.8 CDI85166.1 - 0.036 11.8 12.2 0.038 11.7 8.5 1.1 1 0 0 1 1 1 0 DNA polymerase phi P12 PF12669.2 CDI85166.1 - 0.1 12.7 2.2 0.16 12.1 1.5 1.4 1 0 0 1 1 1 0 Virus attachment protein p12 family TSA PF03249.8 CDI85166.1 - 0.18 10.3 1.1 0.18 10.2 0.7 1.2 1 0 0 1 1 1 0 Type specific antigen Spore_coat_CotO PF14153.1 CDI85166.1 - 0.27 10.6 5.4 0.24 10.8 3.7 1.1 1 0 0 1 1 1 0 Spore coat protein CotO IFT57 PF10498.4 CDI85166.1 - 0.28 9.8 2.7 0.29 9.8 1.9 1.0 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 BUD22 PF09073.5 CDI85166.1 - 0.46 9.4 13.0 0.51 9.3 9.0 1.0 1 0 0 1 1 1 0 BUD22 TRAP_alpha PF03896.11 CDI85166.1 - 0.93 8.4 8.3 1.1 8.2 5.8 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Nop14 PF04147.7 CDI85166.1 - 0.94 7.3 9.1 0.9 7.3 6.3 1.0 1 0 0 1 1 1 0 Nop14-like family Paf1 PF03985.8 CDI85166.1 - 1.2 7.7 8.1 1.1 7.8 5.6 1.1 1 0 0 1 1 1 0 Paf1 RR_TM4-6 PF06459.7 CDI85166.1 - 1.3 8.8 7.0 1.7 8.4 4.9 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Pox_RNA_Pol_19 PF05320.7 CDI85166.1 - 1.5 8.5 5.1 1.7 8.3 3.5 1.2 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit DUF3306 PF11748.3 CDI85166.1 - 3.2 8.4 8.3 3.8 8.1 5.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3306) Radial_spoke PF04712.7 CDI85166.1 - 4.1 6.0 8.9 4.3 5.9 6.1 1.1 1 0 0 1 1 1 0 Radial spokehead-like protein Ribosomal_60s PF00428.14 CDI85167.1 - 0.072 13.4 25.1 0.65 10.4 6.2 3.7 3 1 0 3 3 3 0 60s Acidic ribosomal protein Activator_LAG-3 PF11498.3 CDI85167.1 - 0.092 11.4 56.4 0.14 10.9 39.1 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 SPX PF03105.14 CDI85167.1 - 0.14 11.9 6.9 0.18 11.5 4.8 1.3 1 0 0 1 1 1 0 SPX domain PAT1 PF09770.4 CDI85167.1 - 0.14 10.3 37.8 0.17 10.0 26.2 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 HlyD_2 PF12700.2 CDI85167.1 - 0.32 10.1 10.8 0.33 10.0 7.5 1.2 1 0 0 1 1 1 0 HlyD family secretion protein Med15 PF09606.5 CDI85167.1 - 0.33 9.0 53.6 0.45 8.6 37.1 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal U1snRNP70_N PF12220.3 CDI85167.1 - 0.87 9.9 13.9 2.7 8.3 3.9 2.3 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal Neur_chan_memb PF02932.11 CDI85167.1 - 3.2 7.5 6.8 4.3 7.1 4.7 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region RAB3GAP2_N PF14655.1 CDI85167.1 - 3.5 6.5 30.0 0.8 8.6 7.6 2.1 1 1 1 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus XAP5 PF04921.9 CDI85167.1 - 4.1 6.9 8.1 5.7 6.4 5.6 1.1 1 0 0 1 1 1 0 XAP5, circadian clock regulator Hep_59 PF07052.6 CDI85167.1 - 5 7.5 13.7 1.3 9.4 0.5 2.7 3 0 0 3 3 3 0 Hepatocellular carcinoma-associated antigen 59 EphA2_TM PF14575.1 CDI85167.1 - 6.1 7.3 8.1 19 5.7 0.1 2.5 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Herpes_UL87 PF03043.9 CDI85167.1 - 6.1 5.1 8.2 9.7 4.4 5.7 1.3 1 0 0 1 1 1 0 Herpesvirus UL87 family COX16 PF14138.1 CDI85167.1 - 7.3 6.8 9.5 1.8 8.7 0.5 2.3 2 0 0 2 2 2 0 Cytochrome c oxidase assembly protein COX16 AAA_23 PF13476.1 CDI85167.1 - 7.9 6.7 17.3 13 6.0 12.0 1.3 1 0 0 1 1 1 0 AAA domain DUF2489 PF10675.4 CDI85167.1 - 8.5 6.0 23.4 2.1 8.0 5.9 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2489) Tau95 PF09734.4 CDI85168.1 - 0.46 9.7 0.0 0.46 9.7 0.0 2.1 2 0 0 2 2 2 0 RNA polymerase III transcription factor (TF)IIIC subunit SR-25 PF10500.4 CDI85168.1 - 9.2 5.6 33.6 2.2 7.6 11.6 2.5 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Nha1_C PF08619.5 CDI85169.1 - 0.0007 18.9 22.1 0.00076 18.8 15.3 1.1 1 0 0 1 1 1 1 Alkali metal cation/H+ antiporter Nha1 C terminus DUF2201_N PF13203.1 CDI85169.1 - 0.00073 18.7 23.7 0.00086 18.5 16.4 1.2 1 0 0 1 1 1 1 Putative metallopeptidase domain Rtf2 PF04641.7 CDI85169.1 - 0.0012 18.0 22.0 0.0019 17.4 15.3 1.4 1 0 0 1 1 1 1 Rtf2 RING-finger Herpes_UL87 PF03043.9 CDI85169.1 - 0.019 13.3 9.5 0.02 13.2 6.6 1.1 1 0 0 1 1 1 0 Herpesvirus UL87 family Dapper PF15268.1 CDI85169.1 - 0.14 10.9 31.6 0.18 10.5 21.9 1.2 1 0 0 1 1 1 0 Dapper Ycf1 PF05758.7 CDI85169.1 - 0.17 9.5 32.2 0.21 9.2 22.3 1.1 1 0 0 1 1 1 0 Ycf1 APG6 PF04111.7 CDI85169.1 - 0.26 10.2 35.7 0.35 9.8 24.8 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 Atg14 PF10186.4 CDI85169.1 - 0.32 9.8 34.5 0.38 9.6 23.9 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 SET PF00856.23 CDI85169.1 - 0.43 10.8 4.4 0.54 10.5 3.1 1.3 1 0 0 1 1 1 0 SET domain GAGA_bind PF06217.7 CDI85169.1 - 0.48 10.3 29.4 0.69 9.8 20.4 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family Asp-B-Hydro_N PF05279.6 CDI85169.1 - 0.55 10.0 30.6 0.72 9.6 21.2 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region SpaB_C PF14028.1 CDI85169.1 - 0.71 9.3 7.0 0.93 8.9 4.9 1.1 1 0 0 1 1 1 0 SpaB C-terminal domain DUF1510 PF07423.6 CDI85169.1 - 0.85 8.9 44.7 1.2 8.4 31.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Pilt PF15453.1 CDI85169.1 - 1.3 8.6 29.1 1.8 8.1 20.2 1.2 1 0 0 1 1 1 0 Protein incorporated later into Tight Junctions RR_TM4-6 PF06459.7 CDI85169.1 - 2 8.2 38.3 3.1 7.6 26.6 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF2146 PF10220.4 CDI85169.1 - 2.2 6.1 27.9 2.8 5.8 19.3 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2146) Pox_Ag35 PF03286.9 CDI85169.1 - 2.6 7.5 28.3 5 6.5 19.6 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein FAM60A PF15396.1 CDI85169.1 - 3.3 7.4 30.9 5.8 6.5 21.4 1.3 1 0 0 1 1 1 0 Protein Family FAM60A DUF4613 PF15390.1 CDI85169.1 - 3.7 5.6 21.7 4.7 5.2 15.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) SID-1_RNA_chan PF13965.1 CDI85169.1 - 3.8 5.5 16.8 6.9 4.7 11.7 1.4 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DUF3807 PF12720.2 CDI85169.1 - 4.2 7.5 43.2 6.9 6.7 30.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) Parvo_coat PF00740.13 CDI85169.1 - 5.1 5.9 31.7 6.8 5.5 22.0 1.1 1 0 0 1 1 1 0 Parvovirus coat protein VP2 Med17 PF10156.4 CDI85169.1 - 5.3 5.2 31.4 7.3 4.7 21.8 1.2 1 0 0 1 1 1 0 Subunit 17 of Mediator complex SAGA-Tad1 PF12767.2 CDI85169.1 - 6.5 6.3 37.6 1.2 8.7 23.6 1.5 2 0 0 2 2 2 0 Transcriptional regulator of RNA polII, SAGA, subunit DUF755 PF05501.6 CDI85170.1 - 0.0086 16.1 11.1 0.0086 16.1 7.7 3.9 3 1 0 3 3 3 1 Domain of unknown function (DUF755) PAP1 PF08601.5 CDI85170.1 - 6.6 6.3 28.8 3 7.4 7.5 2.3 2 0 0 2 2 2 0 Transcription factor PAP1 Bestrophin PF01062.16 CDI85170.1 - 8.8 5.1 8.7 0.25 10.2 0.1 2.3 3 0 0 3 3 3 0 Bestrophin, RFP-TM, chloride channel DUF2457 PF10446.4 CDI85171.1 - 0.0012 17.7 30.8 0.0014 17.4 21.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2457) Daxx PF03344.10 CDI85171.1 - 0.0064 15.0 18.4 0.009 14.5 12.7 1.1 1 0 0 1 1 1 1 Daxx Family Apt1 PF10351.4 CDI85171.1 - 0.0074 15.2 4.9 0.0098 14.7 3.4 1.2 1 0 0 1 1 1 1 Golgi-body localisation protein domain Spt5_N PF11942.3 CDI85171.1 - 0.0076 16.8 16.9 0.01 16.4 11.7 1.3 1 0 0 1 1 1 1 Spt5 transcription elongation factor, acidic N-terminal Nop53 PF07767.6 CDI85171.1 - 0.032 13.2 3.6 0.037 13.0 2.5 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) CDC45 PF02724.9 CDI85171.1 - 0.1 10.5 11.1 0.12 10.3 7.7 1.2 1 0 0 1 1 1 0 CDC45-like protein YL1 PF05764.8 CDI85171.1 - 0.14 11.7 10.4 0.2 11.2 7.2 1.2 1 0 0 1 1 1 0 YL1 nuclear protein SDA1 PF05285.7 CDI85171.1 - 0.2 10.9 16.9 0.23 10.7 11.7 1.2 1 0 0 1 1 1 0 SDA1 RRN3 PF05327.6 CDI85171.1 - 1.2 7.1 5.4 1.2 7.1 3.7 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Mpp10 PF04006.7 CDI85171.1 - 1.8 6.8 13.9 2.4 6.4 9.6 1.2 1 0 0 1 1 1 0 Mpp10 protein PLRV_ORF5 PF01690.12 CDI85171.1 - 3.4 6.7 10.3 3.9 6.4 7.1 1.0 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein TFIIF_alpha PF05793.7 CDI85171.1 - 4.4 5.5 22.1 5.5 5.2 15.3 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) BUD22 PF09073.5 CDI85171.1 - 6.4 5.7 24.6 8 5.4 17.0 1.1 1 0 0 1 1 1 0 BUD22 SGT1 PF07093.6 CDI85171.1 - 6.7 4.9 10.7 8.3 4.6 7.4 1.3 1 0 0 1 1 1 0 SGT1 protein Peptidase_S64 PF08192.6 CDI85171.1 - 9.7 4.3 13.3 12 4.0 9.2 1.0 1 0 0 1 1 1 0 Peptidase family S64 DUF4448 PF14610.1 CDI85172.1 - 0.0068 15.9 1.7 0.012 15.1 1.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) Ribosomal_60s PF00428.14 CDI85172.1 - 0.017 15.4 5.0 0.03 14.7 3.4 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein DUF4401 PF14351.1 CDI85172.1 - 0.031 13.2 0.1 0.033 13.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4401) DUF1275 PF06912.6 CDI85172.1 - 0.034 13.3 0.5 0.044 12.9 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1275) DUF912 PF06024.7 CDI85172.1 - 0.037 14.0 15.7 0.039 13.9 1.3 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Mit_KHE1 PF10173.4 CDI85172.1 - 0.089 12.6 7.5 0.14 11.9 5.2 1.3 1 0 0 1 1 1 0 Mitochondrial K+-H+ exchange-related CDC45 PF02724.9 CDI85172.1 - 0.11 10.5 9.5 0.15 10.0 6.6 1.1 1 0 0 1 1 1 0 CDC45-like protein PLRV_ORF5 PF01690.12 CDI85172.1 - 0.12 11.5 12.2 0.13 11.4 8.5 1.0 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein PKD PF00801.15 CDI85172.1 - 0.12 12.1 0.1 0.18 11.5 0.1 1.3 1 0 0 1 1 1 0 PKD domain DUF2407_C PF13373.1 CDI85172.1 - 0.18 11.6 7.6 0.27 11.1 5.3 1.2 1 0 0 1 1 1 0 DUF2407 C-terminal domain DUF3899 PF13038.1 CDI85172.1 - 0.24 11.5 0.0 0.24 11.5 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3899) Nha1_C PF08619.5 CDI85172.1 - 0.32 10.2 15.8 0.37 10.0 10.9 1.0 1 0 0 1 1 1 0 Alkali metal cation/H+ antiporter Nha1 C terminus DUF2208 PF09973.4 CDI85172.1 - 0.35 10.0 1.2 0.31 10.2 0.3 1.3 1 1 0 1 1 1 0 Predicted membrane protein (DUF2208) DUF2956 PF11169.3 CDI85172.1 - 0.45 10.5 27.2 0.15 12.0 4.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2956) CDK5_activator PF03261.10 CDI85172.1 - 0.46 9.7 13.1 0.63 9.3 9.1 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein DUF4045 PF13254.1 CDI85172.1 - 0.48 9.6 12.2 0.55 9.4 8.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Herpes_env PF01673.13 CDI85172.1 - 0.49 8.8 8.5 0.53 8.7 5.9 1.1 1 0 0 1 1 1 0 Herpesvirus putative major envelope glycoprotein DDHD PF02862.12 CDI85172.1 - 0.51 10.1 12.1 0.73 9.5 8.4 1.3 1 0 0 1 1 1 0 DDHD domain eIF-3_zeta PF05091.7 CDI85172.1 - 0.73 8.3 19.3 0.87 8.1 13.4 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Presenilin PF01080.12 CDI85172.1 - 0.98 8.1 6.2 1.1 7.9 4.3 1.1 1 0 0 1 1 1 0 Presenilin Rtf2 PF04641.7 CDI85172.1 - 0.99 8.5 17.6 1.3 8.2 12.2 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger UPF0233 PF06781.7 CDI85172.1 - 1.1 8.9 7.0 1.8 8.2 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0233) SAGA-Tad1 PF12767.2 CDI85172.1 - 1.3 8.6 20.1 1.8 8.1 14.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit DUF2207 PF09972.4 CDI85172.1 - 1.5 7.3 7.3 3.9 5.9 5.1 1.7 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) SPX PF03105.14 CDI85172.1 - 2 8.1 14.0 2.4 7.8 9.7 1.2 1 0 0 1 1 1 0 SPX domain SOBP PF15279.1 CDI85172.1 - 2.2 8.5 22.6 2.6 8.3 15.7 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein HCO3_cotransp PF00955.16 CDI85172.1 - 3.9 6.0 5.9 4.7 5.7 4.1 1.1 1 0 0 1 1 1 0 HCO3- transporter family Spore_YhcN_YlaJ PF09580.5 CDI85172.1 - 4 7.5 17.5 5.8 6.9 12.1 1.3 1 0 0 1 1 1 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) Spc7_N PF15402.1 CDI85172.1 - 4.2 5.2 19.2 5.3 4.9 13.3 1.1 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 Neur_chan_memb PF02932.11 CDI85172.1 - 4.5 7.0 11.5 5.4 6.8 8.0 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF3357 PF11837.3 CDI85172.1 - 4.7 7.1 15.4 0.052 13.4 3.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3357) Hid1 PF12722.2 CDI85172.1 - 5.1 4.6 17.7 5.6 4.5 12.3 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein FAM60A PF15396.1 CDI85172.1 - 5.1 6.7 16.9 6.4 6.4 11.7 1.1 1 0 0 1 1 1 0 Protein Family FAM60A DUF3492 PF11997.3 CDI85172.1 - 5.8 6.3 8.5 6.9 6.1 5.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3492) Tmemb_185A PF10269.4 CDI85172.1 - 6.1 6.3 5.5 0.83 9.2 0.8 1.7 1 1 1 2 2 2 0 Transmembrane Fragile-X-F protein Herpes_DNAp_acc PF04929.7 CDI85172.1 - 6.4 5.6 12.2 7.4 5.4 8.5 1.3 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Ndc1_Nup PF09531.5 CDI85172.1 - 6.5 5.0 16.3 7.6 4.8 11.3 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF4583 PF15190.1 CDI85172.1 - 7.7 6.1 7.5 0.17 11.5 0.6 1.6 2 0 0 2 2 1 0 Domain of unknown function (DUF4583) Otopetrin PF03189.8 CDI85172.1 - 8.1 5.3 7.8 10 4.9 5.4 1.1 1 0 0 1 1 1 0 Otopetrin PA26 PF04636.8 CDI85173.1 - 0.41 9.2 11.3 0.027 13.1 2.1 2.0 2 0 0 2 2 2 0 PA26 p53-induced protein (sestrin) RskA PF10099.4 CDI85173.1 - 0.84 9.3 41.1 0.1 12.3 5.0 3.3 1 1 2 3 3 3 0 Anti-sigma-K factor rskA PAT1 PF09770.4 CDI85173.1 - 0.97 7.5 43.2 1.4 7.0 29.9 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF572 PF04502.8 CDI85173.1 - 1.4 8.0 29.0 0.059 12.5 6.5 2.6 2 1 0 2 2 2 0 Family of unknown function (DUF572) DUF2029 PF09594.5 CDI85174.1 - 0.0063 16.0 7.3 0.008 15.7 5.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2029) R_equi_Vir PF05526.6 CDI85174.1 - 1.2 8.7 9.3 0.69 9.5 0.2 2.0 2 0 0 2 2 2 0 Rhodococcus equi virulence-associated protein BAF1_ABF1 PF04684.8 CDI85175.1 - 0.21 10.3 31.9 0.23 10.2 22.1 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Pex14_N PF04695.8 CDI85175.1 - 1.4 8.9 17.3 1.7 8.7 12.0 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Bud13 PF09736.4 CDI85175.1 - 3.6 7.8 26.2 3.9 7.7 18.2 1.0 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex VIT1 PF01988.14 CDI85175.1 - 9 5.7 8.0 10 5.5 5.5 1.1 1 0 0 1 1 1 0 VIT family RskA PF10099.4 CDI85176.1 - 0.004 16.8 0.5 0.004 16.8 0.3 6.9 3 2 3 6 6 6 1 Anti-sigma-K factor rskA Astro_capsid PF03115.9 CDI85178.1 - 0.17 10.1 10.4 0.23 9.6 7.2 1.2 1 0 0 1 1 1 0 Astrovirus capsid protein precursor rve PF00665.21 CDI85179.1 - 3.3e-17 62.6 0.0 1.1e-16 61.0 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain Chromo PF00385.19 CDI85179.1 - 1.8e-13 49.9 0.0 4.4e-13 48.6 0.0 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain IncA PF04156.9 CDI85180.1 - 1.1e-05 25.1 22.4 1.8e-05 24.4 15.5 1.3 1 0 0 1 1 1 1 IncA protein DUF4138 PF13595.1 CDI85180.1 - 0.0006 18.8 3.8 0.00064 18.7 2.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4138) DDHD PF02862.12 CDI85180.1 - 0.0013 18.6 11.2 0.0013 18.6 7.8 1.1 1 0 0 1 1 1 1 DDHD domain MRP-S31 PF15433.1 CDI85180.1 - 0.0036 16.7 20.6 0.0043 16.5 14.3 1.1 1 0 0 1 1 1 1 Mitochondrial 28S ribosomal protein S31 TraT PF05818.7 CDI85180.1 - 0.0046 16.3 16.4 0.0066 15.8 11.4 1.3 1 0 0 1 1 1 1 Enterobacterial TraT complement resistance protein Peptidase_S15 PF02129.13 CDI85180.1 - 0.0085 15.5 19.0 0.0096 15.3 13.2 1.0 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) DUF677 PF05055.7 CDI85180.1 - 0.009 14.7 0.1 0.011 14.4 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF677) MSP1_C PF07462.6 CDI85180.1 - 0.011 14.2 13.3 0.012 14.0 9.2 1.0 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Raftlin PF15250.1 CDI85180.1 - 0.019 13.5 14.6 0.021 13.3 10.1 1.0 1 0 0 1 1 1 0 Raftlin Med15 PF09606.5 CDI85180.1 - 0.022 12.9 65.6 0.031 12.5 45.5 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF2370 PF10176.4 CDI85180.1 - 0.024 13.9 6.4 0.028 13.7 4.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) HemX PF04375.9 CDI85180.1 - 0.026 13.1 41.8 0.03 12.9 29.0 1.0 1 0 0 1 1 1 0 HemX Serinc PF03348.10 CDI85180.1 - 0.037 12.7 13.5 0.049 12.3 9.3 1.3 1 0 0 1 1 1 0 Serine incorporator (Serinc) Peptidase_S49_N PF08496.5 CDI85180.1 - 0.049 13.4 13.1 0.064 13.0 9.1 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF1510 PF07423.6 CDI85180.1 - 0.052 12.9 15.2 0.058 12.7 10.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) eIF-3_zeta PF05091.7 CDI85180.1 - 0.072 11.6 21.3 0.072 11.7 14.7 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) APG6 PF04111.7 CDI85180.1 - 0.077 12.0 19.4 0.079 11.9 13.5 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 AAA_11 PF13086.1 CDI85180.1 - 0.088 12.3 12.9 0.09 12.3 9.0 1.2 1 0 0 1 1 1 0 AAA domain FAM60A PF15396.1 CDI85180.1 - 0.13 11.9 12.5 0.14 11.8 8.7 1.1 1 0 0 1 1 1 0 Protein Family FAM60A SPX PF03105.14 CDI85180.1 - 0.14 11.9 13.3 0.14 11.9 9.2 1.1 1 0 0 1 1 1 0 SPX domain FLO_LFY PF01698.11 CDI85180.1 - 0.14 11.0 18.5 0.16 10.7 12.8 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein CDC45 PF02724.9 CDI85180.1 - 0.15 10.1 14.0 0.17 9.8 9.7 1.1 1 0 0 1 1 1 0 CDC45-like protein FAM176 PF14851.1 CDI85180.1 - 0.15 11.7 7.9 0.22 11.1 5.5 1.2 1 0 0 1 1 1 0 FAM176 family BTV_NS2 PF04514.7 CDI85180.1 - 0.16 10.8 8.2 0.16 10.8 5.7 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 DUF1632 PF07857.7 CDI85180.1 - 0.17 11.1 1.8 0.21 10.7 1.3 1.1 1 0 0 1 1 1 0 CEO family (DUF1632) Spc7_N PF15402.1 CDI85180.1 - 0.18 9.8 17.9 0.18 9.7 12.4 1.1 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 Draxin PF15550.1 CDI85180.1 - 0.18 11.4 17.2 0.22 11.1 11.9 1.1 1 0 0 1 1 1 0 Draxin DUF2126 PF09899.4 CDI85180.1 - 0.2 9.6 11.2 0.21 9.5 7.8 1.1 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) GPCR_chapero_1 PF11904.3 CDI85180.1 - 0.23 10.5 11.1 0.23 10.5 7.7 1.2 1 0 0 1 1 1 0 GPCR-chaperone DUF2048 PF09752.4 CDI85180.1 - 0.24 10.2 9.6 0.27 10.0 6.6 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2048) DUF4446 PF14584.1 CDI85180.1 - 0.24 11.2 7.6 0.32 10.8 5.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) Neur_chan_memb PF02932.11 CDI85180.1 - 0.24 11.2 10.5 0.26 11.1 7.2 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region SID-1_RNA_chan PF13965.1 CDI85180.1 - 0.25 9.4 8.6 0.26 9.4 5.9 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DUF2828 PF11443.3 CDI85180.1 - 0.25 9.4 13.3 0.29 9.2 9.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Spore_YhcN_YlaJ PF09580.5 CDI85180.1 - 0.27 11.3 15.6 0.32 11.1 10.8 1.2 1 0 0 1 1 1 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) RNA_pol_Rpb1_5 PF04998.12 CDI85180.1 - 0.29 10.3 9.3 0.35 10.0 6.4 1.1 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 DUF4045 PF13254.1 CDI85180.1 - 0.3 10.3 14.2 0.35 10.1 9.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Baculo_PP31 PF05311.6 CDI85180.1 - 0.3 10.3 14.9 0.32 10.2 10.4 1.2 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) AUX_IAA PF02309.11 CDI85180.1 - 0.31 10.7 12.2 0.36 10.5 8.5 1.2 1 0 0 1 1 1 0 AUX/IAA family DUF4011 PF13195.1 CDI85180.1 - 0.35 10.8 9.6 0.39 10.7 6.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4011) Hid1 PF12722.2 CDI85180.1 - 0.43 8.2 16.6 0.45 8.1 11.5 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein OATP PF03137.15 CDI85180.1 - 0.43 8.5 10.6 0.55 8.2 7.3 1.3 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Topoisom_I_N PF02919.10 CDI85180.1 - 0.46 9.7 10.5 0.58 9.4 7.3 1.1 1 0 0 1 1 1 0 Eukaryotic DNA topoisomerase I, DNA binding fragment DUF913 PF06025.7 CDI85180.1 - 0.54 8.9 9.4 0.66 8.6 6.5 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Ycf1 PF05758.7 CDI85180.1 - 0.63 7.6 16.0 0.68 7.5 11.1 1.0 1 0 0 1 1 1 0 Ycf1 AMP-binding PF00501.23 CDI85180.1 - 0.7 8.2 7.5 0.86 7.9 5.2 1.0 1 0 0 1 1 1 0 AMP-binding enzyme PAT1 PF09770.4 CDI85180.1 - 0.92 7.6 50.7 1.1 7.4 35.1 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Med5 PF08689.5 CDI85180.1 - 1 6.9 17.5 1.1 6.8 12.2 1.0 1 0 0 1 1 1 0 Mediator complex subunit Med5 Maf1 PF09174.5 CDI85180.1 - 1.2 9.0 10.5 1.6 8.5 7.2 1.1 1 0 0 1 1 1 0 Maf1 regulator Asp-B-Hydro_N PF05279.6 CDI85180.1 - 1.2 8.9 11.1 1.3 8.8 7.7 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region PPP4R2 PF09184.6 CDI85180.1 - 1.3 8.4 13.0 1.4 8.3 9.0 1.1 1 0 0 1 1 1 0 PPP4R2 PBP1_TM PF14812.1 CDI85180.1 - 1.4 9.2 9.1 2 8.7 6.3 1.2 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal TFIIA PF03153.8 CDI85180.1 - 1.4 8.7 44.8 1.8 8.3 31.0 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Nucleoside_tran PF01733.13 CDI85180.1 - 1.5 7.9 4.8 1.5 7.8 3.4 1.1 1 0 0 1 1 1 0 Nucleoside transporter Plasmodium_Vir PF05795.6 CDI85180.1 - 1.5 7.9 4.9 1.7 7.7 3.4 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Glyco_transf_15 PF01793.11 CDI85180.1 - 1.8 7.4 18.1 2.5 6.9 12.5 1.1 1 0 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase Cellulose_synt PF03552.9 CDI85180.1 - 1.8 6.7 6.5 2 6.6 4.5 1.1 1 0 0 1 1 1 0 Cellulose synthase DUF3449 PF11931.3 CDI85180.1 - 1.8 7.9 18.7 2.4 7.6 13.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3449) HCO3_cotransp PF00955.16 CDI85180.1 - 1.9 7.0 5.1 2 6.9 3.6 1.1 1 0 0 1 1 1 0 HCO3- transporter family Pex16 PF08610.5 CDI85180.1 - 2 7.3 14.1 2.8 6.8 9.8 1.3 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) DUF106 PF01956.11 CDI85180.1 - 2 7.9 14.9 2.6 7.5 10.4 1.2 1 0 0 1 1 1 0 Integral membrane protein DUF106 Sec62 PF03839.11 CDI85180.1 - 2.2 7.6 11.9 2.6 7.3 8.2 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 DUF1980 PF09323.5 CDI85180.1 - 2.3 7.9 12.1 3 7.5 8.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) DUF853 PF05872.7 CDI85180.1 - 2.3 6.4 16.8 3 6.0 11.6 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) DUF342 PF03961.8 CDI85180.1 - 2.4 6.4 10.1 2.5 6.4 7.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF4578 PF15147.1 CDI85180.1 - 2.4 8.5 22.4 3.6 7.9 15.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4578) Herpes_DNAp_acc PF04929.7 CDI85180.1 - 2.4 7.0 13.8 2.7 6.8 9.6 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Peptidase_U57 PF05582.7 CDI85180.1 - 2.9 6.7 14.3 3.5 6.5 9.9 1.1 1 0 0 1 1 1 0 YabG peptidase U57 GAGA_bind PF06217.7 CDI85180.1 - 3 7.7 18.5 3.4 7.5 12.8 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family DUF2215 PF10225.4 CDI85180.1 - 3.1 7.1 10.7 3.9 6.8 7.4 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) Ctr PF04145.10 CDI85180.1 - 3.2 7.8 16.3 4.8 7.2 11.3 1.3 1 1 0 1 1 1 0 Ctr copper transporter family DUF4220 PF13968.1 CDI85180.1 - 3.2 6.7 9.0 3.5 6.6 6.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4220) Presenilin PF01080.12 CDI85180.1 - 3.3 6.4 15.0 3.9 6.2 10.4 1.0 1 0 0 1 1 1 0 Presenilin CDK5_activator PF03261.10 CDI85180.1 - 3.4 6.9 16.2 3.8 6.7 11.3 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein Bac_luciferase PF00296.15 CDI85180.1 - 3.5 6.6 16.1 5.9 5.9 11.1 1.4 1 1 0 1 1 1 0 Luciferase-like monooxygenase PMSI1 PF15322.1 CDI85180.1 - 3.6 6.6 21.4 5 6.1 14.8 1.3 1 1 0 1 1 1 0 Protein missing in infertile sperm 1, putative Paramyxo_ncap PF00973.14 CDI85180.1 - 4.2 5.9 15.5 4.7 5.7 10.8 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Peptidase_S64 PF08192.6 CDI85180.1 - 5.2 5.2 17.0 6 5.0 11.8 1.0 1 0 0 1 1 1 0 Peptidase family S64 YABBY PF04690.8 CDI85180.1 - 5.2 7.2 13.4 6.6 6.9 9.3 1.2 1 0 0 1 1 1 0 YABBY protein Cyto_heme_lyase PF01265.12 CDI85180.1 - 5.6 6.4 18.6 6.5 6.2 12.9 1.2 1 0 0 1 1 1 0 Cytochrome c/c1 heme lyase PXA PF02194.10 CDI85180.1 - 6 6.3 11.5 6.5 6.2 7.9 1.2 1 0 0 1 1 1 0 PXA domain Bud13 PF09736.4 CDI85180.1 - 7 6.9 25.6 11 6.2 17.7 1.3 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex Parvo_coat PF00740.13 CDI85180.1 - 7 5.4 24.9 8.1 5.2 17.3 1.0 1 0 0 1 1 1 0 Parvovirus coat protein VP2 FAM91_C PF14648.1 CDI85180.1 - 7 5.3 11.7 7.7 5.2 8.1 1.0 1 0 0 1 1 1 0 FAM91 C-terminus YjgP_YjgQ PF03739.9 CDI85180.1 - 7.1 5.2 7.6 7.4 5.2 5.3 1.2 1 0 0 1 1 1 0 Predicted permease YjgP/YjgQ family DUF4484 PF14831.1 CDI85180.1 - 7.3 6.6 14.2 15 5.6 9.6 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4484) MMR1 PF08505.5 CDI85180.1 - 7.5 6.5 26.6 8.8 6.2 18.4 1.2 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein DUF3450 PF11932.3 CDI85180.1 - 7.5 5.7 46.0 9.1 5.4 31.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF3381 PF11861.3 CDI85180.1 - 8.2 5.9 18.5 10 5.5 12.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) DUF1387 PF07139.6 CDI85180.1 - 8.3 5.9 14.6 9.3 5.7 10.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) Prismane PF03063.15 CDI85180.1 - 8.8 4.5 12.2 10 4.3 8.5 1.0 1 0 0 1 1 1 0 Prismane/CO dehydrogenase family Dicty_REP PF05086.7 CDI85180.1 - 9.3 3.8 11.6 9.2 3.8 8.1 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Band_3_cyto PF07565.8 CDI85180.1 - 9.6 5.6 20.5 13 5.2 14.2 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain PGM_PMM_I PF02878.11 CDI85181.1 - 3.8e-12 45.8 0.0 4.3e-06 26.2 0.0 2.4 2 0 0 2 2 2 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I N6_N4_Mtase PF01555.13 CDI85181.1 - 0.00044 19.8 0.0 0.049 13.1 0.0 3.0 1 1 0 1 1 1 1 DNA methylase FimP PF09766.4 CDI85181.1 - 0.0028 16.7 5.3 0.0028 16.7 3.7 4.1 3 1 1 4 4 3 1 Fms-interacting protein DUF177 PF02620.12 CDI85181.1 - 0.005 16.8 3.6 0.005 16.8 2.5 3.1 3 0 0 3 3 3 1 Uncharacterized ACR, COG1399 OmpH PF03938.9 CDI85181.1 - 0.014 15.3 84.5 0.3 11.0 15.6 3.2 3 0 0 3 3 3 0 Outer membrane protein (OmpH-like) BRF1 PF07741.8 CDI85181.1 - 0.032 14.4 0.3 0.032 14.4 0.2 4.5 4 1 0 5 5 4 0 Brf1-like TBP-binding domain SPX PF03105.14 CDI85181.1 - 0.042 13.6 30.3 0.033 13.9 11.2 2.4 1 1 1 2 2 2 0 SPX domain DUF2899 PF11449.3 CDI85181.1 - 0.064 12.4 12.4 0.068 12.3 0.2 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF2899) DUF4064 PF13273.1 CDI85181.1 - 0.076 13.1 0.2 0.076 13.1 0.2 4.0 3 1 0 3 3 2 0 Protein of unknown function (DUF4064) MRP-S31 PF15433.1 CDI85181.1 - 0.21 10.9 36.8 1.5 8.1 3.3 3.2 3 0 0 3 3 3 0 Mitochondrial 28S ribosomal protein S31 DUF4512 PF14975.1 CDI85181.1 - 0.3 11.9 19.4 0.11 13.3 1.5 3.6 4 0 0 4 4 3 0 Domain of unknown function (DUF4512) Bac_luciferase PF00296.15 CDI85181.1 - 5.3 6.0 12.3 0.37 9.8 1.4 3.1 3 0 0 3 3 3 0 Luciferase-like monooxygenase SGT1 PF07093.6 CDI85181.1 - 6.9 4.9 35.9 1.6 6.9 16.4 2.3 2 0 0 2 2 2 0 SGT1 protein OAD_gamma PF04277.8 CDI85181.1 - 7.2 7.0 12.0 7.9 6.9 0.0 4.3 5 0 0 5 5 5 0 Oxaloacetate decarboxylase, gamma chain FLO_LFY PF01698.11 CDI85181.1 - 7.6 5.2 34.3 1.3 7.7 7.9 3.1 3 0 0 3 3 3 0 Floricaula / Leafy protein DUF2244 PF10003.4 CDI85182.1 - 0.00058 19.2 0.9 0.00058 19.2 0.6 1.8 1 1 1 2 2 2 1 Integral membrane protein (DUF2244) SpoIIIAH PF12685.2 CDI85182.1 - 0.0013 18.2 0.7 0.0019 17.7 0.5 1.3 1 0 0 1 1 1 1 SpoIIIAH-like protein TMEM51 PF15345.1 CDI85182.1 - 0.0073 16.0 7.3 0.0073 16.0 5.1 1.4 1 1 0 1 1 1 1 Transmembrane protein 51 Protocadherin PF08374.6 CDI85182.1 - 0.0077 15.8 0.8 0.0082 15.7 0.5 1.2 1 0 0 1 1 1 1 Protocadherin Ribosomal_60s PF00428.14 CDI85182.1 - 0.03 14.7 7.6 0.042 14.2 5.3 1.3 1 0 0 1 1 1 0 60s Acidic ribosomal protein RSN1_TM PF13967.1 CDI85182.1 - 0.033 13.7 0.9 0.04 13.4 0.6 1.2 1 0 0 1 1 1 0 Late exocytosis, associated with Golgi transport DUF2621 PF11084.3 CDI85182.1 - 0.063 12.9 0.3 0.072 12.7 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2621) DUF3260 PF11658.3 CDI85182.1 - 0.44 8.6 5.9 0.44 8.6 4.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3260) V_ATPase_I PF01496.14 CDI85182.1 - 0.48 8.2 9.6 0.56 7.9 6.7 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Activator_LAG-3 PF11498.3 CDI85182.1 - 0.78 8.4 18.1 0.93 8.1 12.5 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 UPF0104 PF03706.8 CDI85182.1 - 0.91 8.7 12.0 1.9 7.6 8.3 1.6 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0104) TALPID3 PF15324.1 CDI85182.1 - 0.94 6.7 9.2 1.2 6.4 6.4 1.1 1 0 0 1 1 1 0 Hedgehog signalling target 7tm_7 PF08395.7 CDI85182.1 - 1.1 8.2 11.7 1.3 7.9 8.1 1.1 1 0 0 1 1 1 0 7tm Chemosensory receptor DUF3138 PF11336.3 CDI85182.1 - 1.3 7.1 10.1 1.3 7.0 7.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) DUF1430 PF07242.6 CDI85182.1 - 1.7 8.7 10.8 3.3 7.8 7.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1430) Cytochrom_C_asm PF01578.15 CDI85182.1 - 2.4 7.6 8.3 1.8 8.0 4.8 1.6 1 1 0 1 1 1 0 Cytochrome C assembly protein Shadoo PF14999.1 CDI85182.1 - 2.5 7.9 7.6 3.9 7.3 5.2 1.2 1 0 0 1 1 1 0 Shadow of prion protein, neuroprotective Mycobact_memb PF05423.8 CDI85182.1 - 3.8 7.2 5.0 1.7 8.4 1.2 1.8 1 1 1 2 2 2 0 Mycobacterium membrane protein PigN PF04987.9 CDI85182.1 - 5.2 5.5 14.6 5.6 5.4 10.1 1.0 1 0 0 1 1 1 0 Phosphatidylinositolglycan class N (PIG-N) ETRAMP PF09716.5 CDI85182.1 - 8.3 6.4 12.4 57 3.7 8.6 2.3 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) EphA2_TM PF14575.1 CDI85182.1 - 8.5 6.8 13.7 0.094 13.1 2.5 2.5 1 1 2 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain Prenyltrans_2 PF13249.1 CDI85183.1 - 0.21 12.0 2.0 0.43 10.9 1.4 1.5 1 0 0 1 1 1 0 Prenyltransferase-like RBM39linker PF15519.1 CDI85183.1 - 0.35 11.1 0.1 0.35 11.1 0.0 2.0 3 0 0 3 3 3 0 linker between RRM2 and RRM3 domains in RBM39 protein RskA PF10099.4 CDI85184.1 - 0.11 12.1 12.4 0.13 12.0 8.6 1.1 1 0 0 1 1 1 0 Anti-sigma-K factor rskA SR-25 PF10500.4 CDI85184.1 - 0.17 11.3 10.8 0.19 11.1 7.5 1.0 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Ctr PF04145.10 CDI85184.1 - 0.29 11.1 4.6 0.37 10.8 3.2 1.2 1 0 0 1 1 1 0 Ctr copper transporter family PepSY_2 PF13670.1 CDI85184.1 - 0.32 10.9 9.6 0.46 10.4 6.6 1.3 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain DUF3824 PF12868.2 CDI85184.1 - 0.65 10.9 9.5 0.83 10.5 6.6 1.2 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) Trp_oprn_chp PF09534.5 CDI85184.1 - 0.84 9.2 6.9 0.91 9.1 4.8 1.0 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) MelC1 PF06236.6 CDI85184.1 - 1.2 9.1 7.0 1.4 8.8 4.8 1.1 1 0 0 1 1 1 0 Tyrosinase co-factor MelC1 DUF2217 PF10265.4 CDI85184.1 - 1.8 7.2 8.0 2 7.1 5.6 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) Ribosomal_60s PF00428.14 CDI85184.1 - 1.9 8.9 8.0 2.4 8.6 5.5 1.2 1 0 0 1 1 1 0 60s Acidic ribosomal protein R_equi_Vir PF05526.6 CDI85184.1 - 3.2 7.3 8.5 3.3 7.3 5.9 1.0 1 0 0 1 1 1 0 Rhodococcus equi virulence-associated protein HemX PF04375.9 CDI85184.1 - 4 5.9 24.4 4.4 5.7 16.9 1.0 1 0 0 1 1 1 0 HemX DUF3123 PF11321.3 CDI85184.1 - 5.1 7.4 6.7 5.8 7.2 4.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3123) DUF1675 PF07897.6 CDI85184.1 - 6.8 6.4 11.8 7.8 6.2 8.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) DUF1764 PF08576.5 CDI85184.1 - 8.8 7.1 18.7 11 6.8 13.0 1.2 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) Ketoacyl-synt_2 PF13723.1 CDI85184.1 - 9.7 5.3 16.1 11 5.1 11.1 1.1 1 0 0 1 1 1 0 Beta-ketoacyl synthase, N-terminal domain PAT1 PF09770.4 CDI85185.1 - 0.019 13.2 38.9 0.029 12.6 27.0 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Ndc1_Nup PF09531.5 CDI85185.1 - 0.052 11.9 10.3 0.099 11.0 7.2 1.4 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup FLO_LFY PF01698.11 CDI85185.1 - 0.28 9.9 20.4 0.49 9.1 14.2 1.3 1 0 0 1 1 1 0 Floricaula / Leafy protein RR_TM4-6 PF06459.7 CDI85185.1 - 2.1 8.1 24.6 4.4 7.1 17.1 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Band_3_cyto PF07565.8 CDI85185.1 - 2.9 7.3 18.9 6.6 6.1 13.1 1.5 1 0 0 1 1 1 0 Band 3 cytoplasmic domain eIF-3_zeta PF05091.7 CDI85185.1 - 4.5 5.7 33.2 1.4 7.4 21.1 1.4 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) SidE PF12252.3 CDI85186.1 - 0.041 11.2 0.1 0.056 10.7 0.1 1.3 1 1 0 1 1 1 0 Dot/Icm substrate protein N2227 PF07942.7 CDI85186.1 - 0.048 12.6 0.0 0.092 11.6 0.0 1.4 1 0 0 1 1 1 0 N2227-like protein HalX PF08663.5 CDI85186.1 - 0.053 13.5 0.0 0.74 9.8 0.0 2.4 2 0 0 2 2 2 0 HalX domain NPR3 PF03666.8 CDI85188.1 - 5.5 5.4 14.6 6 5.2 10.1 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 IncA PF04156.9 CDI85189.1 - 0.0013 18.3 4.2 0.002 17.7 2.9 1.3 1 0 0 1 1 1 1 IncA protein DUF4245 PF14030.1 CDI85189.1 - 0.0013 18.5 6.8 0.0017 18.1 4.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4245) Spt20 PF12090.3 CDI85189.1 - 0.0028 17.0 1.6 0.0028 17.0 1.1 1.1 1 0 0 1 1 1 1 Spt20 family FimP PF09766.4 CDI85189.1 - 0.0033 16.5 5.2 0.0036 16.4 3.6 1.1 1 0 0 1 1 1 1 Fms-interacting protein RAB3GAP2_N PF14655.1 CDI85189.1 - 0.015 14.3 3.6 0.015 14.2 2.5 1.1 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Med15 PF09606.5 CDI85189.1 - 0.022 12.9 27.2 0.025 12.7 18.9 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Suf PF05843.9 CDI85189.1 - 0.028 14.1 4.8 0.027 14.2 3.3 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) FHIPEP PF00771.15 CDI85189.1 - 0.061 11.6 3.6 0.072 11.4 2.5 1.1 1 0 0 1 1 1 0 FHIPEP family Serinc PF03348.10 CDI85189.1 - 0.084 11.5 1.1 0.093 11.4 0.7 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) Band_3_cyto PF07565.8 CDI85189.1 - 0.43 10.0 4.0 0.59 9.5 2.7 1.3 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Presenilin PF01080.12 CDI85189.1 - 0.47 9.2 1.8 0.51 9.1 1.3 1.2 1 0 0 1 1 1 0 Presenilin PHD_3 PF13922.1 CDI85189.1 - 0.57 10.4 11.3 1.6 9.0 7.8 1.8 1 0 0 1 1 1 0 PHD domain of transcriptional enhancer, Asx Peptidase_S15 PF02129.13 CDI85189.1 - 0.85 8.9 7.1 1 8.7 4.9 1.2 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Pex16 PF08610.5 CDI85189.1 - 1 8.2 4.8 1.4 7.8 3.3 1.1 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) TFIIA PF03153.8 CDI85189.1 - 1.3 8.8 19.2 1.6 8.5 13.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Scs3p PF10261.4 CDI85189.1 - 2.2 7.2 5.0 3.2 6.7 3.5 1.2 1 0 0 1 1 1 0 Inositol phospholipid synthesis and fat-storage-inducing TM PAT1 PF09770.4 CDI85189.1 - 2.3 6.3 19.6 2.6 6.1 13.6 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 PDGLE PF13190.1 CDI85189.1 - 3.2 7.4 8.8 5.6 6.7 3.8 2.1 1 1 1 2 2 2 0 PDGLE domain Activator_LAG-3 PF11498.3 CDI85189.1 - 3.8 6.1 24.1 5.1 5.7 16.7 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 DivIC PF04977.10 CDI85189.1 - 4.1 6.9 11.1 6.1 6.4 7.7 1.2 1 0 0 1 1 1 0 Septum formation initiator Glyoxalase_2 PF12681.2 CDI85190.1 - 0.00025 21.6 1.0 2.3 8.8 0.0 3.6 2 1 0 2 2 2 2 Glyoxalase-like domain PAT1 PF09770.4 CDI85190.1 - 1.5 7.0 75.1 2.3 6.3 52.0 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 GAGA_bind PF06217.7 CDI85190.1 - 4.5 7.1 29.0 14 5.5 20.1 1.9 1 0 0 1 1 1 0 GAGA binding protein-like family IF3_C PF00707.17 CDI85191.1 - 6.2e-14 51.4 1.1 3.3e-13 49.1 0.0 2.0 1 1 0 2 2 2 1 Translation initiation factor IF-3, C-terminal domain DUF844 PF05815.6 CDI85191.1 - 0.03 13.1 5.0 0.038 12.8 3.5 1.1 1 0 0 1 1 1 0 Baculovirus protein of unknown function (DUF844) Peptidase_S49_N PF08496.5 CDI85191.1 - 0.51 10.1 5.1 0.94 9.2 3.6 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Suf PF05843.9 CDI85191.1 - 2 8.0 11.2 2.5 7.7 7.8 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) PAT1 PF09770.4 CDI85191.1 - 7.3 4.7 28.0 7.8 4.5 19.4 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SR-25 PF10500.4 CDI85192.1 - 0.00037 20.0 2.7 0.00037 20.0 1.9 3.7 3 0 0 3 3 3 1 Nuclear RNA-splicing-associated protein CD20 PF04103.10 CDI85192.1 - 0.41 10.5 5.5 0.12 12.3 1.0 2.3 2 0 0 2 2 2 0 CD20-like family SprA-related PF12118.3 CDI85193.1 - 0.01 15.2 51.0 0.015 14.6 35.4 1.2 1 0 0 1 1 1 0 SprA-related family UDG PF03167.14 CDI85193.1 - 0.011 15.2 0.2 0.013 14.9 0.1 1.3 1 0 0 1 1 1 0 Uracil DNA glycosylase superfamily RAP1 PF07218.6 CDI85193.1 - 0.012 13.8 13.4 0.012 13.6 9.3 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) SAGA-Tad1 PF12767.2 CDI85193.1 - 0.014 15.0 31.3 0.016 14.8 21.7 1.1 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit NAM-associated PF14303.1 CDI85193.1 - 0.083 13.1 25.6 0.12 12.7 17.7 1.2 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain AAA_23 PF13476.1 CDI85193.1 - 0.21 11.8 27.9 0.28 11.5 19.3 1.1 1 0 0 1 1 1 0 AAA domain Med15 PF09606.5 CDI85193.1 - 0.7 8.0 62.4 0.82 7.7 43.3 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Corona_nucleoca PF00937.13 CDI85193.1 - 0.76 8.6 35.9 1.2 8.0 24.9 1.3 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein Utp14 PF04615.8 CDI85193.1 - 0.82 7.7 31.4 1.1 7.3 21.7 1.1 1 0 0 1 1 1 0 Utp14 protein SOBP PF15279.1 CDI85193.1 - 1.1 9.5 30.8 1.4 9.2 21.3 1.0 1 0 0 1 1 1 0 Sine oculis-binding protein Secretin_N_2 PF07655.8 CDI85193.1 - 2.2 8.7 40.8 2.9 8.3 2.9 2.2 2 0 0 2 2 2 0 Secretin N-terminal domain DUF4349 PF14257.1 CDI85193.1 - 2.5 7.2 20.7 2.6 7.2 5.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4349) CAF-1_p150 PF11600.3 CDI85193.1 - 4.7 6.5 46.8 7.8 5.8 32.4 1.4 1 1 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Suc_Fer-like PF06999.7 CDI85193.1 - 9.2 6.2 13.8 16 5.4 9.5 1.3 1 0 0 1 1 1 0 Sucrase/ferredoxin-like DUF4045 PF13254.1 CDI85194.1 - 2 7.5 42.5 2.5 7.3 29.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) PAT1 PF09770.4 CDI85194.1 - 3 5.9 106.5 3.1 5.9 73.9 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Utp14 PF04615.8 CDI85194.1 - 6.9 4.7 54.9 7.9 4.5 38.0 1.0 1 0 0 1 1 1 0 Utp14 protein SR-25 PF10500.4 CDI85195.1 - 0.0024 17.3 24.9 0.0024 17.3 17.2 1.7 1 1 1 2 2 2 1 Nuclear RNA-splicing-associated protein Med15 PF09606.5 CDI85195.1 - 1.8 6.6 110.6 2.3 6.3 76.7 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal HNOBA PF07701.9 CDI85196.1 - 0.028 13.6 0.2 0.028 13.6 0.2 1.1 1 0 0 1 1 1 0 Heme NO binding associated DUF3568 PF12092.3 CDI85196.1 - 0.13 11.9 0.5 0.15 11.8 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3568) B2-adapt-app_C PF09066.5 CDI85196.1 - 0.14 12.0 1.9 0.15 11.9 0.3 1.7 1 1 1 2 2 2 0 Beta2-adaptin appendage, C-terminal sub-domain DUF2489 PF10675.4 CDI85196.1 - 0.17 11.5 4.9 0.2 11.3 3.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2489) Med3 PF11593.3 CDI85196.1 - 0.6 9.2 7.7 0.58 9.3 5.3 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Med15 PF09606.5 CDI85196.1 - 0.74 7.9 11.9 0.74 7.9 8.2 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal PHD_3 PF13922.1 CDI85196.1 - 1.1 9.5 4.4 1.5 9.0 3.1 1.3 1 0 0 1 1 1 0 PHD domain of transcriptional enhancer, Asx Androgen_recep PF02166.11 CDI85196.1 - 1.8 7.3 6.4 1.9 7.2 4.4 1.1 1 0 0 1 1 1 0 Androgen receptor BAF1_ABF1 PF04684.8 CDI85196.1 - 2 7.1 7.2 1.9 7.2 5.0 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor TSA PF03249.8 CDI85196.1 - 7.4 4.9 9.0 6.8 5.0 6.2 1.1 1 0 0 1 1 1 0 Type specific antigen Tim54 PF11711.3 CDI85197.1 - 0.00095 17.8 6.5 0.0012 17.5 4.5 1.1 1 0 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 Potyvirid-P3 PF13608.1 CDI85197.1 - 0.0036 16.5 11.6 0.0046 16.1 8.0 1.1 1 0 0 1 1 1 1 Protein P3 of Potyviral polyprotein RNA_pol_L PF01193.19 CDI85197.1 - 0.0045 16.0 0.0 0.0081 15.2 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain TctA PF01970.11 CDI85197.1 - 0.0058 15.0 0.0 0.0083 14.5 0.0 1.3 1 0 0 1 1 1 1 Tripartite tricarboxylate transporter TctA family SOBP PF15279.1 CDI85197.1 - 0.012 16.0 14.5 0.022 15.1 10.0 1.4 1 0 0 1 1 1 0 Sine oculis-binding protein PP_M1 PF03012.9 CDI85197.1 - 0.015 14.6 15.3 0.019 14.3 10.6 1.1 1 0 0 1 1 1 0 Phosphoprotein DRY_EERY PF09750.4 CDI85197.1 - 0.019 15.0 7.7 0.019 15.0 5.3 2.0 2 0 0 2 2 2 0 Alternative splicing regulator LicD PF04991.8 CDI85197.1 - 0.025 14.6 1.3 0.031 14.3 0.9 1.0 1 0 0 1 1 1 0 LicD family DUF3464 PF11947.3 CDI85197.1 - 0.059 12.8 11.0 0.038 13.4 5.7 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3464) BPL_N PF09825.4 CDI85197.1 - 0.24 10.1 6.9 0.29 9.8 4.8 1.1 1 0 0 1 1 1 0 Biotin-protein ligase, N terminal Draxin PF15550.1 CDI85197.1 - 0.36 10.4 19.7 0.51 9.9 13.7 1.2 1 0 0 1 1 1 0 Draxin DUF572 PF04502.8 CDI85197.1 - 0.53 9.4 21.6 0.21 10.7 12.2 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF572) Peptidase_S64 PF08192.6 CDI85197.1 - 0.61 8.3 17.6 5 5.3 11.0 2.0 2 0 0 2 2 2 0 Peptidase family S64 Gag_spuma PF03276.9 CDI85197.1 - 0.92 7.7 31.7 0.041 12.2 16.2 2.1 2 0 0 2 2 2 0 Spumavirus gag protein LIM_bind PF01803.11 CDI85197.1 - 1.3 8.1 24.7 6 5.9 13.3 2.1 2 0 0 2 2 2 0 LIM-domain binding protein Paf1 PF03985.8 CDI85197.1 - 1.6 7.4 20.5 0.087 11.5 10.2 1.7 2 0 0 2 2 2 0 Paf1 Sporozoite_P67 PF05642.6 CDI85197.1 - 1.6 6.5 9.3 1.8 6.3 6.5 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF1764 PF08576.5 CDI85197.1 - 2 9.2 21.5 1.2 9.9 11.5 2.3 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF1764) CRT10 PF08728.5 CDI85197.1 - 2.2 6.1 9.9 2.5 6.0 6.9 1.0 1 0 0 1 1 1 0 CRT10 UPF0560 PF10577.4 CDI85197.1 - 2.3 6.3 37.6 2.4 6.3 1.0 2.0 2 0 0 2 2 2 0 Uncharacterised protein family UPF0560 DUF543 PF04418.7 CDI85197.1 - 2.3 8.2 0.0 2.3 8.2 0.0 3.3 2 1 0 2 2 1 0 Domain of unknown function (DUF543) Band_3_cyto PF07565.8 CDI85197.1 - 2.6 7.4 21.6 2 7.8 12.3 2.0 2 0 0 2 2 2 0 Band 3 cytoplasmic domain Dehalogenase PF13486.1 CDI85197.1 - 2.7 7.3 11.7 6.4 6.1 7.3 1.8 2 0 0 2 2 2 0 Reductive dehalogenase subunit DUF4175 PF13779.1 CDI85197.1 - 3 5.4 53.6 0.28 8.8 30.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4175) Cellulose_synt PF03552.9 CDI85197.1 - 3 6.0 5.5 4.2 5.5 3.8 1.2 1 0 0 1 1 1 0 Cellulose synthase Pal1 PF08316.6 CDI85197.1 - 3.6 8.0 12.7 4.6 7.6 6.9 2.0 2 0 0 2 2 2 0 Pal1 cell morphology protein MecA PF05389.7 CDI85197.1 - 4.4 6.7 14.7 1.6 8.2 8.1 1.7 2 0 0 2 2 2 0 Negative regulator of genetic competence (MecA) Otopetrin PF03189.8 CDI85197.1 - 4.5 6.1 14.9 5 6.0 10.0 1.4 1 1 0 1 1 1 0 Otopetrin DUF4602 PF15375.1 CDI85197.1 - 4.6 7.3 23.8 6.6 6.7 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4602) Spore_YhcN_YlaJ PF09580.5 CDI85197.1 - 4.6 7.3 25.5 2.1 8.4 0.0 2.1 2 0 0 2 2 2 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) SelP_N PF04592.9 CDI85197.1 - 5.1 6.3 22.8 0.3 10.4 11.3 1.9 2 0 0 2 2 2 0 Selenoprotein P, N terminal region DUF2457 PF10446.4 CDI85197.1 - 5.4 5.6 15.2 0.84 8.2 7.5 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) DUF966 PF06136.8 CDI85197.1 - 5.6 6.2 21.2 2.8 7.2 12.7 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF966) FAM60A PF15396.1 CDI85197.1 - 5.8 6.5 15.8 2.7 7.6 8.5 1.9 2 0 0 2 2 2 0 Protein Family FAM60A DUF2052 PF09747.4 CDI85197.1 - 5.9 6.7 25.4 1.1 9.1 13.7 1.9 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) Baculo_PP31 PF05311.6 CDI85197.1 - 8.3 5.5 20.2 4.7 6.4 11.9 1.8 2 0 0 2 2 2 0 Baculovirus 33KDa late protein (PP31) SID-1_RNA_chan PF13965.1 CDI85197.1 - 8.6 4.3 10.2 11 3.9 7.1 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 eIF-5_eIF-2B PF01873.12 CDI85198.1 - 5e-23 81.1 0.0 5.8e-23 80.9 0.0 1.0 1 0 0 1 1 1 1 Domain found in IF2B/IF5 Metallophos_2 PF12850.2 CDI85199.1 - 1.8e-20 73.3 0.0 2.2e-20 73.0 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 CDI85199.1 - 0.0011 18.4 1.0 0.0043 16.4 0.7 2.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase CHCH PF06747.8 CDI85200.1 - 2.5e-05 24.0 3.1 5.4e-05 22.9 2.0 1.7 1 1 1 2 2 2 2 CHCH domain Keratin_matx PF04579.7 CDI85201.1 - 0.037 14.3 0.3 0.065 13.5 0.2 1.4 1 0 0 1 1 1 0 Keratin, high-sulphur matrix protein Ribosomal_L7Ae PF01248.21 CDI85202.1 - 6.8e-23 79.9 1.3 1.3e-22 79.1 0.9 1.5 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.6 CDI85202.1 - 0.036 13.9 0.0 0.066 13.0 0.0 1.4 1 0 0 1 1 1 0 RNase P subunit Pop3 CAF-1_p150 PF11600.3 CDI85203.1 - 5.5e-05 22.6 8.5 5.5e-05 22.6 5.9 3.1 2 1 1 3 3 3 2 Chromatin assembly factor 1 complex p150 subunit, N-terminal Cwf_Cwc_15 PF04889.7 CDI85203.1 - 0.01 15.5 25.6 0.018 14.7 6.2 2.2 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein DUF4630 PF15443.1 CDI85203.1 - 0.015 15.1 3.5 0.015 15.1 2.4 2.8 2 1 0 3 3 3 0 Domain of unknown function (DUF4630) Med15 PF09606.5 CDI85203.1 - 0.03 12.5 51.1 0.036 12.2 35.5 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF572 PF04502.8 CDI85203.1 - 0.071 12.3 38.2 0.56 9.3 11.5 2.1 1 1 1 2 2 2 0 Family of unknown function (DUF572) DUF4175 PF13779.1 CDI85203.1 - 0.28 8.8 43.1 0.56 7.8 13.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4175) TFIIA PF03153.8 CDI85203.1 - 0.48 10.2 37.4 0.8 9.5 26.0 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF3446 PF11928.3 CDI85203.1 - 0.91 9.7 28.2 0.98 9.6 4.2 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3446) DUF3043 PF11241.3 CDI85203.1 - 3.5 7.2 12.2 1.2 8.6 0.8 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3043) Peptidase_S49_N PF08496.5 CDI85203.1 - 4.1 7.1 12.1 4.5 7.0 1.8 2.4 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Hid1 PF12722.2 CDI85205.1 - 0.018 12.7 6.9 0.019 12.7 4.8 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SAGA-Tad1 PF12767.2 CDI85205.1 - 0.03 13.9 10.5 0.037 13.6 7.3 1.3 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit NPR3 PF03666.8 CDI85205.1 - 0.047 12.2 6.6 0.061 11.8 4.5 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Band_3_cyto PF07565.8 CDI85205.1 - 0.063 12.7 9.4 0.085 12.3 6.5 1.3 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Ycf1 PF05758.7 CDI85205.1 - 0.13 10.0 7.9 0.13 9.9 5.5 1.0 1 0 0 1 1 1 0 Ycf1 Plasmodium_Vir PF05795.6 CDI85205.1 - 0.13 11.4 2.7 0.17 11.0 1.9 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein DUF2126 PF09899.4 CDI85205.1 - 0.13 10.2 6.5 0.14 10.1 4.5 1.1 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) PixA PF12306.3 CDI85205.1 - 0.17 11.6 4.3 0.26 11.1 3.0 1.2 1 0 0 1 1 1 0 Inclusion body protein DUF2370 PF10176.4 CDI85205.1 - 0.21 10.9 4.3 0.42 9.9 3.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) NABP PF07990.7 CDI85205.1 - 0.24 10.6 10.5 0.31 10.2 7.3 1.1 1 0 0 1 1 1 0 Nucleic acid binding protein NABP vMSA PF00695.14 CDI85205.1 - 0.28 10.3 5.4 0.33 10.1 3.8 1.2 1 0 0 1 1 1 0 Major surface antigen from hepadnavirus PH_4 PF15404.1 CDI85205.1 - 0.49 9.8 5.8 0.94 8.9 4.0 1.5 1 0 0 1 1 1 0 Pleckstrin homology domain OATP PF03137.15 CDI85205.1 - 0.67 7.9 6.8 0.93 7.4 4.7 1.3 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Peptidase_U57 PF05582.7 CDI85205.1 - 0.88 8.4 5.1 1.1 8.1 3.6 1.3 1 0 0 1 1 1 0 YabG peptidase U57 DDRGK PF09756.4 CDI85205.1 - 0.96 8.8 19.2 1.6 8.1 13.3 1.3 1 0 0 1 1 1 0 DDRGK domain Macoilin PF09726.4 CDI85205.1 - 1.1 7.4 13.3 1.4 7.1 9.2 1.1 1 0 0 1 1 1 0 Transmembrane protein DUF913 PF06025.7 CDI85205.1 - 1.2 7.8 12.5 0.55 8.9 7.4 1.3 1 1 0 1 1 1 0 Domain of Unknown Function (DUF913) YppG PF14179.1 CDI85205.1 - 1.2 9.7 33.7 2.1 9.0 23.4 1.3 1 0 0 1 1 1 0 YppG-like protein eIF-3_zeta PF05091.7 CDI85205.1 - 1.3 7.5 14.4 1.8 7.0 10.0 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Cellulose_synt PF03552.9 CDI85205.1 - 1.5 7.0 4.0 1.7 6.8 2.8 1.1 1 0 0 1 1 1 0 Cellulose synthase SID-1_RNA_chan PF13965.1 CDI85205.1 - 1.5 6.8 5.1 2.2 6.3 3.6 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 zf-DHHC PF01529.15 CDI85205.1 - 1.8 7.8 8.7 3.6 6.9 6.0 1.5 1 0 0 1 1 1 0 DHHC palmitoyltransferase Sec62 PF03839.11 CDI85205.1 - 2 7.7 5.7 2.6 7.3 3.9 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 Tim54 PF11711.3 CDI85205.1 - 2.2 6.7 9.8 3.6 6.0 6.8 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DUF2215 PF10225.4 CDI85205.1 - 2.5 7.4 6.6 3.9 6.8 4.6 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) Peptidase_S49_N PF08496.5 CDI85205.1 - 3.3 7.5 8.8 7.8 6.2 6.1 1.6 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Baculo_PP31 PF05311.6 CDI85205.1 - 3.5 6.8 11.9 5.8 6.0 8.2 1.3 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) Glyco_transf_15 PF01793.11 CDI85205.1 - 4.7 6.0 13.3 7.2 5.4 9.2 1.2 1 0 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase PAT1 PF09770.4 CDI85205.1 - 4.8 5.2 41.6 0.062 11.5 23.6 1.5 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 Ndc1_Nup PF09531.5 CDI85205.1 - 5 5.4 10.8 6.7 5.0 7.5 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Peptidase_S64 PF08192.6 CDI85205.1 - 6.5 4.9 12.6 7.6 4.7 8.7 1.1 1 0 0 1 1 1 0 Peptidase family S64 UPF0560 PF10577.4 CDI85205.1 - 6.8 4.8 21.2 9.6 4.3 14.7 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 DUF3260 PF11658.3 CDI85205.1 - 7.4 4.5 15.6 7.1 4.6 10.3 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3260) Paf1 PF03985.8 CDI85205.1 - 8.1 5.0 19.2 11 4.6 13.3 1.1 1 0 0 1 1 1 0 Paf1 Spore_coat_CotO PF14153.1 CDI85205.1 - 8.7 5.7 24.6 0.29 10.5 12.8 1.7 2 1 0 2 2 2 0 Spore coat protein CotO CRF1 PF10380.4 CDI85205.1 - 9.3 6.6 9.5 18 5.6 6.6 1.5 1 0 0 1 1 1 0 Transcription factor CRF1 Pex16 PF08610.5 CDI85205.1 - 9.9 5.0 11.6 14 4.5 8.0 1.2 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) SR-25 PF10500.4 CDI85206.1 - 0.00043 19.8 13.8 0.00052 19.5 9.5 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein LicD PF04991.8 CDI85206.1 - 0.11 12.6 2.1 0.13 12.3 1.4 1.1 1 0 0 1 1 1 0 LicD family CDK5_activator PF03261.10 CDI85206.1 - 0.51 9.6 16.9 0.58 9.4 11.7 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein CPSF100_C PF13299.1 CDI85206.1 - 0.51 10.5 17.0 0.67 10.1 11.8 1.3 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal DUF2828 PF11443.3 CDI85206.1 - 0.51 8.4 12.4 0.57 8.3 8.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) DUF4080 PF13311.1 CDI85206.1 - 0.52 10.3 9.5 0.64 10.0 6.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4080) PAT1 PF09770.4 CDI85206.1 - 0.53 8.4 55.7 0.61 8.2 38.6 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 GAGA_bind PF06217.7 CDI85206.1 - 0.59 10.0 20.7 0.63 9.9 14.4 1.0 1 0 0 1 1 1 0 GAGA binding protein-like family MRP-S31 PF15433.1 CDI85206.1 - 0.61 9.4 25.5 0.81 9.0 17.7 1.2 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 Peptidase_U57 PF05582.7 CDI85206.1 - 0.61 8.9 14.6 0.87 8.5 10.1 1.3 1 0 0 1 1 1 0 YabG peptidase U57 FAM60A PF15396.1 CDI85206.1 - 0.73 9.5 15.9 0.98 9.1 11.0 1.3 1 0 0 1 1 1 0 Protein Family FAM60A eIF-3_zeta PF05091.7 CDI85206.1 - 0.88 8.1 29.2 1 7.9 20.2 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF4045 PF13254.1 CDI85206.1 - 1 8.5 20.2 1.3 8.2 14.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Ribosomal_60s PF00428.14 CDI85206.1 - 1.3 9.4 15.9 3 8.2 11.0 1.7 1 0 0 1 1 1 0 60s Acidic ribosomal protein AUX_IAA PF02309.11 CDI85206.1 - 1.3 8.6 19.1 1.6 8.4 13.2 1.2 1 0 0 1 1 1 0 AUX/IAA family RR_TM4-6 PF06459.7 CDI85206.1 - 1.4 8.7 21.7 2 8.2 15.0 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Med15 PF09606.5 CDI85206.1 - 1.5 6.9 86.4 1.8 6.6 59.9 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Raftlin PF15250.1 CDI85206.1 - 1.7 7.1 19.8 1.9 6.8 13.7 1.2 1 0 0 1 1 1 0 Raftlin Nha1_C PF08619.5 CDI85206.1 - 2.4 7.3 25.3 2.7 7.1 17.5 1.1 1 0 0 1 1 1 0 Alkali metal cation/H+ antiporter Nha1 C terminus Cyto_heme_lyase PF01265.12 CDI85206.1 - 2.8 7.4 18.6 3.4 7.1 12.9 1.3 1 0 0 1 1 1 0 Cytochrome c/c1 heme lyase CDC45 PF02724.9 CDI85206.1 - 3.9 5.3 24.6 4.4 5.2 17.1 1.0 1 0 0 1 1 1 0 CDC45-like protein Herpes_DNAp_acc PF04929.7 CDI85206.1 - 4.6 6.0 21.9 5.7 5.8 15.2 1.0 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Draxin PF15550.1 CDI85206.1 - 4.8 6.7 17.2 6 6.4 12.0 1.2 1 0 0 1 1 1 0 Draxin BTV_NS2 PF04514.7 CDI85206.1 - 4.9 5.9 17.6 5.8 5.6 12.2 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 DUF2146 PF10220.4 CDI85206.1 - 5.1 4.9 20.8 5.7 4.7 14.4 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2146) MSP1_C PF07462.6 CDI85206.1 - 6 5.1 15.1 6.7 4.9 10.5 1.1 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Presenilin PF01080.12 CDI85206.1 - 6.8 5.3 17.0 8.3 5.1 11.8 1.3 1 0 0 1 1 1 0 Presenilin Apt1 PF10351.4 CDI85206.1 - 9.7 4.9 24.6 12 4.6 17.1 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain Ank_5 PF13857.1 CDI85207.1 - 2.8e-07 30.5 0.0 8.4e-07 29.0 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.25 CDI85207.1 - 4e-06 26.3 0.1 9.3e-06 25.2 0.1 1.6 1 0 0 1 1 1 1 Ankyrin repeat Ank_2 PF12796.2 CDI85207.1 - 1.2e-05 25.5 1.5 2.4e-05 24.5 0.2 2.1 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 CDI85207.1 - 0.00047 20.5 0.0 0.00099 19.5 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 CDI85207.1 - 0.002 18.1 0.1 0.005 16.9 0.1 1.7 1 0 0 1 1 1 1 Ankyrin repeat BAF1_ABF1 PF04684.8 CDI85208.1 - 1.4e-05 24.2 23.9 1.4e-05 24.2 16.6 4.7 3 2 1 4 4 4 2 BAF1 / ABF1 chromatin reorganising factor ADP_ribosyl_GH PF03747.9 CDI85208.1 - 4.2 7.0 15.6 1.5 8.5 0.4 3.3 3 0 0 3 3 3 0 ADP-ribosylglycohydrolase Med15 PF09606.5 CDI85208.1 - 9.6 4.2 116.2 1.4 7.0 53.2 2.1 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal RskA PF10099.4 CDI85209.1 - 0.02 14.6 16.9 0.024 14.3 11.7 1.1 1 0 0 1 1 1 0 Anti-sigma-K factor rskA Med15 PF09606.5 CDI85209.1 - 0.022 12.9 33.0 0.024 12.8 22.9 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal FimP PF09766.4 CDI85209.1 - 0.055 12.5 14.0 0.052 12.6 9.7 1.1 1 0 0 1 1 1 0 Fms-interacting protein DUF4342 PF14242.1 CDI85209.1 - 0.24 11.2 1.2 0.39 10.5 0.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4342) AAA_23 PF13476.1 CDI85209.1 - 0.41 10.9 7.7 0.41 10.9 5.3 1.2 1 0 0 1 1 1 0 AAA domain Suf PF05843.9 CDI85209.1 - 0.93 9.1 17.0 1 8.9 11.8 1.0 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) CoA_transf_3 PF02515.12 CDI85209.1 - 1 8.5 9.6 1.1 8.4 6.6 1.1 1 0 0 1 1 1 0 CoA-transferase family III DUF3881 PF12997.2 CDI85209.1 - 1.6 7.6 7.1 4.7 6.1 3.0 2.0 1 1 1 2 2 2 0 Domain of unknown function, E. rectale Gene description (DUF3881) RAB3GAP2_N PF14655.1 CDI85209.1 - 1.7 7.5 11.6 1.8 7.4 8.1 1.2 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus DUF4207 PF13904.1 CDI85209.1 - 1.7 7.9 24.2 2 7.7 16.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4207) DUF2232 PF09991.4 CDI85209.1 - 1.9 7.4 4.8 2.2 7.2 3.3 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) Peptidase_S21 PF00716.12 CDI85209.1 - 2.1 7.5 13.4 2.2 7.5 9.3 1.0 1 0 0 1 1 1 0 Assemblin (Peptidase family S21) TFIIA PF03153.8 CDI85209.1 - 2.5 7.9 27.8 2.7 7.7 19.2 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Serinc PF03348.10 CDI85209.1 - 3 6.4 12.9 3.2 6.3 9.0 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) RR_TM4-6 PF06459.7 CDI85209.1 - 4 7.2 13.3 4.7 7.0 9.2 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 R_equi_Vir PF05526.6 CDI85209.1 - 5.9 6.5 12.9 6.6 6.3 8.9 1.2 1 0 0 1 1 1 0 Rhodococcus equi virulence-associated protein FLO_LFY PF01698.11 CDI85209.1 - 6.3 5.5 12.3 6.8 5.4 8.5 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein Bul1_N PF04425.7 CDI85209.1 - 7.8 4.9 13.0 8.9 4.7 9.0 1.0 1 0 0 1 1 1 0 Bul1 N terminus Fes1 PF08609.5 CDI85211.1 - 0.4 11.1 5.9 0.94 9.9 0.6 3.1 3 0 0 3 3 3 0 Nucleotide exchange factor Fes1 DUF3446 PF11928.3 CDI85211.1 - 4.1 7.6 31.7 2.2 8.5 10.8 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF3446) CDC27 PF09507.5 CDI85212.1 - 0.091 11.9 39.9 0.095 11.9 27.7 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Utp14 PF04615.8 CDI85212.1 - 1.3 7.0 45.0 1.4 7.0 31.2 1.0 1 0 0 1 1 1 0 Utp14 protein PAT1 PF09770.4 CDI85212.1 - 2.4 6.2 82.5 2.6 6.1 57.2 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 CAF-1_p150 PF11600.3 CDI85212.1 - 3.8 6.8 51.2 4.9 6.4 35.5 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF1510 PF07423.6 CDI85213.1 - 0.42 9.9 34.3 0.46 9.8 23.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) VID27 PF08553.5 CDI85213.1 - 7.2 4.6 30.4 8.4 4.4 21.1 1.0 1 0 0 1 1 1 0 VID27 cytoplasmic protein CDC45 PF02724.9 CDI85213.1 - 9.5 4.1 36.1 11 3.8 25.0 1.0 1 0 0 1 1 1 0 CDC45-like protein Folate_carrier PF01770.13 CDI85214.1 - 0.13 10.7 4.8 0.25 9.7 3.3 1.4 1 0 0 1 1 1 0 Reduced folate carrier DUF1253 PF06862.7 CDI85214.1 - 0.51 8.6 5.3 0.75 8.1 3.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1253) SR-25 PF10500.4 CDI85216.1 - 0.0022 17.5 29.9 0.031 13.7 14.2 2.0 1 1 1 2 2 2 2 Nuclear RNA-splicing-associated protein Cwf_Cwc_15 PF04889.7 CDI85216.1 - 0.099 12.3 14.3 0.12 12.1 9.9 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein SprA-related PF12118.3 CDI85216.1 - 0.53 9.5 28.1 0.67 9.2 19.5 1.1 1 0 0 1 1 1 0 SprA-related family FSA_C PF10479.4 CDI85216.1 - 1.7 6.6 10.4 0.35 8.8 4.7 1.5 1 1 1 2 2 2 0 Fragile site-associated protein C-terminus Suf PF05843.9 CDI85216.1 - 2.7 7.6 15.9 3 7.4 11.0 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) GET2 PF08690.5 CDI85217.1 - 0.14 11.3 4.9 0.23 10.6 3.4 1.3 1 0 0 1 1 1 0 GET complex subunit GET2 CAF-1_p150 PF11600.3 CDI85217.1 - 1.5 8.1 7.5 2.2 7.5 5.2 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF4207 PF13904.1 CDI85218.1 - 0.0064 15.8 21.8 0.0064 15.8 15.1 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4207) Med15 PF09606.5 CDI85218.1 - 0.022 13.0 65.5 0.024 12.8 45.4 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal SOBP PF15279.1 CDI85218.1 - 0.18 12.1 24.8 0.21 11.9 17.2 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein DUF4220 PF13968.1 CDI85218.1 - 0.2 10.7 9.7 0.25 10.4 6.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4220) CCDC84 PF14968.1 CDI85218.1 - 0.24 10.8 26.9 0.3 10.5 18.6 1.0 1 0 0 1 1 1 0 Coiled coil protein 84 CDK5_activator PF03261.10 CDI85218.1 - 0.25 10.6 23.6 0.34 10.1 16.3 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein TFIIA PF03153.8 CDI85218.1 - 0.28 11.0 41.0 0.4 10.5 28.4 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Hid1 PF12722.2 CDI85218.1 - 0.31 8.6 28.1 0.4 8.2 19.5 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Ycf1 PF05758.7 CDI85218.1 - 0.34 8.5 18.1 0.41 8.2 12.5 1.1 1 0 0 1 1 1 0 Ycf1 PAT1 PF09770.4 CDI85218.1 - 1.4 7.0 56.2 1.8 6.6 39.0 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 CAF-1_p150 PF11600.3 CDI85218.1 - 2.7 7.3 38.2 12 5.1 26.5 1.8 1 1 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Asp-B-Hydro_N PF05279.6 CDI85218.1 - 3.7 7.3 21.8 5.5 6.7 15.1 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region MRP-S31 PF15433.1 CDI85218.1 - 3.8 6.8 28.9 0.52 9.6 17.3 1.5 2 0 0 2 2 2 0 Mitochondrial 28S ribosomal protein S31 Utp14 PF04615.8 CDI85218.1 - 6.5 4.7 30.5 8 4.4 21.2 1.1 1 0 0 1 1 1 0 Utp14 protein LMBR1 PF04791.11 CDI85218.1 - 7.7 4.9 14.2 9.3 4.7 9.8 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein Borrelia_P83 PF05262.6 CDI85218.1 - 7.9 4.6 25.8 9.5 4.3 17.9 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein Calreticulin PF00262.13 CDI85220.1 - 7.3e-17 61.0 0.0 2e-14 53.0 0.0 2.8 1 1 1 2 2 2 2 Calreticulin family Cullin PF00888.17 CDI85221.1 - 8.9e-13 47.6 0.0 3.4e-11 42.4 0.0 2.3 2 1 0 2 2 2 2 Cullin family Cullin_Nedd8 PF10557.4 CDI85221.1 - 5.6e-09 35.7 3.1 1.4e-08 34.3 0.7 2.5 2 1 0 2 2 2 1 Cullin protein neddylation domain Dynein_heavy PF03028.10 CDI85223.1 - 2.6e-125 419.1 8.3 7.7e-76 255.6 0.1 6.5 3 1 3 6 6 5 4 Dynein heavy chain and region D6 of dynein motor DHC_N2 PF08393.8 CDI85223.1 - 2.2e-119 398.6 1.6 2.2e-119 398.6 1.1 3.7 5 0 0 5 5 5 1 Dynein heavy chain, N-terminal region 2 AAA_6 PF12774.2 CDI85223.1 - 1.2e-78 263.7 3.2 4.2e-70 235.8 0.2 3.4 3 0 0 3 3 3 2 Hydrolytic ATP binding site of dynein motor region D1 AAA_7 PF12775.2 CDI85223.1 - 2.6e-52 177.5 0.0 5.8e-52 176.4 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region D3 MT PF12777.2 CDI85223.1 - 5.8e-47 160.1 12.5 9e-46 156.1 4.9 2.3 2 0 0 2 2 2 2 Microtubule-binding stalk of dynein motor AAA_8 PF12780.2 CDI85223.1 - 5.6e-35 120.6 0.0 1.2e-31 109.6 0.0 3.0 2 1 1 3 3 3 2 P-loop containing dynein motor region D4 AAA_9 PF12781.2 CDI85223.1 - 6.1e-30 103.7 10.1 2.4e-18 65.8 0.1 3.0 2 1 1 3 3 3 2 ATP-binding dynein motor region D5 AAA_5 PF07728.9 CDI85223.1 - 1.5e-22 79.7 0.0 2.5e-05 24.0 0.0 6.4 5 1 0 5 5 4 3 AAA domain (dynein-related subfamily) AAA PF00004.24 CDI85223.1 - 2.9e-09 37.2 0.4 0.021 15.0 0.0 5.4 5 0 0 5 5 4 3 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 CDI85223.1 - 1.2e-06 28.7 0.2 2.6 8.2 0.0 5.4 5 0 0 5 5 5 1 AAA domain AAA_17 PF13207.1 CDI85223.1 - 4.7e-05 24.2 0.4 0.029 15.2 0.0 4.5 4 0 0 4 4 3 1 AAA domain AAA_19 PF13245.1 CDI85223.1 - 0.00082 19.0 3.4 0.22 11.2 0.2 3.8 3 0 0 3 3 3 1 Part of AAA domain RNA_helicase PF00910.17 CDI85223.1 - 0.0011 19.0 0.0 0.51 10.5 0.0 3.6 3 0 0 3 3 3 1 RNA helicase Zeta_toxin PF06414.7 CDI85223.1 - 0.0013 17.8 1.2 0.12 11.4 0.0 3.3 3 0 0 3 3 3 1 Zeta toxin AAA_18 PF13238.1 CDI85223.1 - 0.0013 19.0 0.1 0.86 9.9 0.0 3.9 4 0 0 4 4 3 1 AAA domain Mg_chelatase PF01078.16 CDI85223.1 - 0.0018 17.4 0.7 3 6.9 0.0 3.8 4 0 0 4 4 4 1 Magnesium chelatase, subunit ChlI AAA_25 PF13481.1 CDI85223.1 - 0.013 14.8 1.4 1.9 7.8 0.1 3.7 3 0 0 3 3 3 0 AAA domain UPF0079 PF02367.12 CDI85223.1 - 0.022 14.3 1.3 4.2 7.0 0.1 3.4 3 0 0 3 3 3 0 Uncharacterised P-loop hydrolase UPF0079 DEAD PF00270.24 CDI85223.1 - 0.025 14.0 2.4 3.6 7.0 0.0 3.8 4 0 0 4 4 4 0 DEAD/DEAH box helicase T2SE PF00437.15 CDI85223.1 - 0.056 12.3 7.5 0.55 9.0 0.0 3.6 4 0 0 4 4 3 0 Type II/IV secretion system protein DUF755 PF05501.6 CDI85225.1 - 0.021 14.9 6.3 0.021 14.9 4.4 4.2 5 0 0 5 5 5 0 Domain of unknown function (DUF755) GHMP_kinases_N PF00288.21 CDI85225.1 - 0.099 12.7 0.6 0.099 12.7 0.4 3.5 4 0 0 4 4 4 0 GHMP kinases N terminal domain TIP_N PF12457.3 CDI85225.1 - 0.12 12.5 0.1 0.12 12.5 0.1 2.7 3 1 0 3 3 3 0 Tuftelin interacting protein N terminal LSM14 PF12701.2 CDI85226.1 - 7.8e-28 96.1 0.5 1.3e-27 95.4 0.0 1.6 2 0 0 2 2 2 1 Scd6-like Sm domain FDF PF09532.5 CDI85226.1 - 7.1e-06 26.5 14.1 0.0029 18.1 3.5 2.7 1 1 1 2 2 2 2 FDF domain SM-ATX PF14438.1 CDI85226.1 - 4.6e-05 23.2 0.0 8.5e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Ataxin 2 SM domain PRP38_assoc PF12871.2 CDI85228.1 - 0.4 11.2 98.4 8.5 6.9 28.1 2.4 1 1 1 2 2 2 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term MIP-T3 PF10243.4 CDI85228.1 - 2.4 6.5 45.4 2.6 6.4 31.5 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Hexokinase_1 PF00349.16 CDI85229.1 - 0.0066 15.7 0.9 0.0083 15.4 0.6 1.1 1 0 0 1 1 1 1 Hexokinase NST1 PF13945.1 CDI85229.1 - 0.016 15.2 10.6 0.021 14.9 7.3 1.2 1 0 0 1 1 1 0 Salt tolerance down-regulator Rifin_STEVOR PF02009.11 CDI85229.1 - 0.079 12.5 3.6 0.1 12.2 2.5 1.1 1 0 0 1 1 1 0 Rifin/stevor family MCPVI PF02993.9 CDI85229.1 - 0.094 12.8 16.7 0.11 12.6 11.5 1.0 1 0 0 1 1 1 0 Minor capsid protein VI FAT PF02259.18 CDI85229.1 - 0.1 11.5 9.1 0.12 11.3 6.3 1.1 1 0 0 1 1 1 0 FAT domain HI0933_like PF03486.9 CDI85229.1 - 0.22 9.9 6.6 0.22 9.9 4.6 1.1 1 0 0 1 1 1 0 HI0933-like protein FAM220 PF15487.1 CDI85229.1 - 0.44 9.8 6.6 0.5 9.7 4.6 1.1 1 0 0 1 1 1 0 FAM220 family DUF4557 PF15101.1 CDI85229.1 - 0.46 10.3 15.1 0.53 10.1 10.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) F-protein PF00469.15 CDI85229.1 - 0.83 8.9 5.6 0.84 8.9 3.9 1.1 1 0 0 1 1 1 0 Negative factor, (F-Protein) or Nef Neur_chan_memb PF02932.11 CDI85229.1 - 0.86 9.4 6.9 0.93 9.3 4.8 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Sporozoite_P67 PF05642.6 CDI85229.1 - 0.94 7.2 11.0 1 7.1 7.7 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF3418 PF11898.3 CDI85229.1 - 1 7.6 14.0 1.5 7.1 9.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3418) Ycf1 PF05758.7 CDI85229.1 - 1.2 6.7 6.4 1 6.9 4.4 1.0 1 0 0 1 1 1 0 Ycf1 Band_3_cyto PF07565.8 CDI85229.1 - 1.3 8.4 7.6 1.3 8.4 5.2 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain DUF3373 PF11853.3 CDI85229.1 - 1.3 7.4 7.3 1.5 7.2 5.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) GlnE PF03710.10 CDI85229.1 - 1.4 8.1 11.4 1.5 7.9 7.9 1.0 1 0 0 1 1 1 0 Glutamate-ammonia ligase adenylyltransferase DDHD PF02862.12 CDI85229.1 - 1.4 8.6 6.5 1.4 8.6 4.5 1.2 1 0 0 1 1 1 0 DDHD domain DUF3533 PF12051.3 CDI85229.1 - 1.6 7.4 7.1 1.6 7.3 4.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3533) Pal1 PF08316.6 CDI85229.1 - 2 8.8 6.3 2.7 8.4 4.4 1.2 1 0 0 1 1 1 0 Pal1 cell morphology protein Atg14 PF10186.4 CDI85229.1 - 2.2 7.1 14.8 2.5 6.9 10.2 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Hid1 PF12722.2 CDI85229.1 - 2.2 5.8 8.9 2 6.0 6.2 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF1266 PF06889.6 CDI85229.1 - 2.3 8.0 6.4 3 7.5 4.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1266) ABC2_membrane_3 PF12698.2 CDI85229.1 - 3 6.7 4.3 3.8 6.4 3.0 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein Mnd1 PF03962.10 CDI85229.1 - 3.1 7.4 15.1 3.8 7.1 10.5 1.1 1 0 0 1 1 1 0 Mnd1 family Helicase_RecD PF05127.9 CDI85229.1 - 3.1 7.3 6.7 4.5 6.8 4.7 1.4 1 0 0 1 1 1 0 Helicase HD_3 PF13023.1 CDI85229.1 - 3.2 7.4 8.5 3.7 7.2 5.9 1.1 1 0 0 1 1 1 0 HD domain EcsC PF12787.2 CDI85229.1 - 3.3 7.0 11.2 4 6.7 7.8 1.1 1 0 0 1 1 1 0 EcsC protein family EspB PF05802.6 CDI85229.1 - 3.7 6.4 16.7 4.7 6.0 11.6 1.1 1 0 0 1 1 1 0 Enterobacterial EspB protein Mcm10 PF09332.6 CDI85229.1 - 4.2 6.6 13.1 5 6.3 9.1 1.1 1 0 0 1 1 1 0 Mcm10 replication factor DUF2924 PF11149.3 CDI85229.1 - 6.4 6.8 10.4 9.1 6.3 7.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2924) DUF966 PF06136.8 CDI85229.1 - 8.5 5.6 12.5 10 5.4 8.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Glyco_transf_15 PF01793.11 CDI85229.1 - 8.5 5.2 9.6 9.9 4.9 6.6 1.1 1 0 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase TruD PF01142.13 CDI85231.1 - 3.9e-39 134.4 9.4 3.7e-21 75.2 0.0 4.9 5 0 0 5 5 5 3 tRNA pseudouridine synthase D (TruD) HEM4 PF02602.10 CDI85232.1 - 2.6e-07 30.1 6.5 2.6e-07 30.1 4.5 2.5 1 1 0 2 2 2 1 Uroporphyrinogen-III synthase HemD PAT1 PF09770.4 CDI85232.1 - 0.013 13.8 27.2 0.016 13.4 18.9 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 AAA_23 PF13476.1 CDI85232.1 - 0.21 11.8 4.7 0.34 11.1 3.2 1.2 1 0 0 1 1 1 0 AAA domain Hid1 PF12722.2 CDI85232.1 - 0.39 8.3 3.0 0.52 7.9 2.1 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF913 PF06025.7 CDI85232.1 - 0.97 8.1 6.7 1.1 7.9 3.9 1.7 1 1 0 1 1 1 0 Domain of Unknown Function (DUF913) FLO_LFY PF01698.11 CDI85232.1 - 1.3 7.7 8.5 2.1 7.0 5.9 1.3 1 0 0 1 1 1 0 Floricaula / Leafy protein DUF2722 PF10846.3 CDI85232.1 - 4.4 6.2 20.3 0.29 10.0 0.4 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2722) DUF2201 PF09967.4 CDI85233.1 - 0.32 11.0 4.6 0.96 9.4 3.2 1.8 1 0 0 1 1 1 0 VWA-like domain (DUF2201) Dehydrin PF00257.14 CDI85234.1 - 0.00013 22.3 19.2 0.02 15.2 0.1 3.1 1 1 0 2 2 2 2 Dehydrin Plasmodium_Vir PF05795.6 CDI85234.1 - 0.0029 16.8 4.7 0.35 10.0 0.2 2.3 2 1 0 2 2 2 2 Plasmodium vivax Vir protein CAF-1_p150 PF11600.3 CDI85234.1 - 0.0076 15.6 25.6 0.0076 15.6 17.7 3.3 3 0 0 3 3 3 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal SNAPc_SNAP43 PF09808.4 CDI85234.1 - 0.062 12.9 0.0 0.062 12.9 0.0 2.9 3 0 0 3 3 3 0 Small nuclear RNA activating complex (SNAPc), subunit SNAP43 Zip PF02535.17 CDI85234.1 - 0.18 10.7 7.3 0.017 14.1 1.0 2.1 2 0 0 2 2 2 0 ZIP Zinc transporter YjgP_YjgQ PF03739.9 CDI85234.1 - 0.2 10.3 6.2 0.013 14.2 0.6 1.8 2 1 0 2 2 2 0 Predicted permease YjgP/YjgQ family Activator_LAG-3 PF11498.3 CDI85234.1 - 0.39 9.4 66.5 0.37 9.4 31.3 2.3 2 0 0 2 2 2 0 Transcriptional activator LAG-3 Peptidase_S49_N PF08496.5 CDI85234.1 - 0.99 9.1 13.6 1.1 9.0 5.7 2.5 2 0 0 2 2 2 0 Peptidase family S49 N-terminal zf-DHHC PF01529.15 CDI85234.1 - 0.99 8.7 11.6 0.72 9.2 2.3 2.4 2 0 0 2 2 2 0 DHHC palmitoyltransferase U1snRNP70_N PF12220.3 CDI85234.1 - 4 7.8 28.6 1.2 9.4 2.0 2.4 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal Anoctamin PF04547.7 CDI85234.1 - 5.9 5.4 11.4 2.5 6.6 5.9 1.7 2 0 0 2 2 2 0 Calcium-activated chloride channel Lipoprotein_10 PF03202.8 CDI85236.1 - 0.049 13.6 7.8 0.055 13.4 5.4 1.1 1 0 0 1 1 1 0 Putative mycoplasma lipoprotein, C-terminal region Malectin_like PF12819.2 CDI85236.1 - 0.21 10.6 0.2 0.21 10.6 0.1 1.8 1 1 1 2 2 2 0 Carbohydrate-binding protein of the ER PBP1_TM PF14812.1 CDI85236.1 - 1.2 9.4 8.2 2.2 8.6 5.7 1.5 1 1 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Prp18 PF02840.10 CDI85236.1 - 4.4 7.1 12.0 6.3 6.6 8.3 1.4 1 1 0 1 1 1 0 Prp18 domain DUF349 PF03993.7 CDI85236.1 - 8.3 6.6 10.1 14 5.9 7.0 1.5 1 1 0 1 1 1 0 Domain of Unknown Function (DUF349) DUF3994 PF13159.1 CDI85236.1 - 8.5 6.6 9.1 2.7 8.3 2.9 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF3994) YfhO PF09586.5 CDI85237.1 - 0.00087 17.4 9.4 0.00087 17.4 6.5 1.3 1 1 0 1 1 1 1 Bacterial membrane protein YfhO LMBR1 PF04791.11 CDI85237.1 - 0.0015 17.2 1.7 0.0015 17.2 1.2 2.2 1 1 1 2 2 1 1 LMBR1-like membrane protein FA_desaturase PF00487.19 CDI85237.1 - 0.0015 18.0 1.2 0.15 11.5 0.0 3.2 2 1 1 3 3 3 1 Fatty acid desaturase DUF788 PF05620.6 CDI85237.1 - 0.0022 17.9 2.0 0.0022 17.9 1.4 3.6 4 0 0 4 4 4 1 Protein of unknown function (DUF788) GBV-C_env PF12786.2 CDI85237.1 - 0.0022 16.5 4.9 0.0048 15.4 3.4 1.5 1 0 0 1 1 1 1 GB virus C genotype envelope Shisa PF13908.1 CDI85237.1 - 0.0024 18.0 6.2 0.0024 18.0 4.3 3.8 4 1 0 4 4 3 1 Wnt and FGF inhibitory regulator Tic20 PF09685.5 CDI85237.1 - 0.0026 17.7 2.5 0.0068 16.3 1.7 1.6 1 0 0 1 1 1 1 Tic20-like protein IncA PF04156.9 CDI85237.1 - 0.0034 16.9 15.7 0.0034 16.9 10.9 5.7 3 1 1 4 4 1 1 IncA protein Pex24p PF06398.6 CDI85237.1 - 0.0097 14.7 0.1 0.019 13.7 0.1 1.4 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin DUF1510 PF07423.6 CDI85237.1 - 0.012 14.9 9.7 0.012 14.9 6.8 3.4 3 1 0 3 3 3 0 Protein of unknown function (DUF1510) OAD_gamma PF04277.8 CDI85237.1 - 0.016 15.5 0.1 0.016 15.5 0.1 6.6 4 2 1 5 5 2 0 Oxaloacetate decarboxylase, gamma chain FAM176 PF14851.1 CDI85237.1 - 0.23 11.1 8.7 0.2 11.3 1.1 3.3 3 0 0 3 3 3 0 FAM176 family PIG-P PF08510.7 CDI85237.1 - 0.45 10.1 3.3 0.34 10.5 0.5 2.1 2 0 0 2 2 2 0 PIG-P Tetraspannin PF00335.15 CDI85237.1 - 0.51 9.5 5.5 0.42 9.8 2.5 1.7 2 0 0 2 2 2 0 Tetraspanin family DUF1980 PF09323.5 CDI85237.1 - 0.66 9.6 9.7 0.07 12.8 1.5 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF1980) SID-1_RNA_chan PF13965.1 CDI85237.1 - 0.81 7.7 9.0 0.15 10.1 3.7 1.6 1 1 1 2 2 2 0 dsRNA-gated channel SID-1 Neur_chan_memb PF02932.11 CDI85237.1 - 0.99 9.2 13.2 0.27 11.0 2.3 2.9 2 1 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Neur PF00064.13 CDI85237.1 - 1.4 6.9 5.7 0.88 7.5 2.5 1.6 2 0 0 2 2 2 0 Neuraminidase DUF4446 PF14584.1 CDI85237.1 - 2.5 7.9 17.4 0.06 13.1 4.7 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF4446) DNAJ_related PF12339.3 CDI85239.1 - 0.0022 17.8 0.1 0.0022 17.8 0.1 1.9 2 0 0 2 2 2 1 DNA-J related protein Phostensin_N PF13916.1 CDI85239.1 - 1.4 8.9 9.9 5 7.1 3.3 2.8 2 0 0 2 2 2 0 PP1-regulatory protein, Phostensin N-terminal DUF4048 PF13257.1 CDI85240.1 - 0.012 15.2 6.2 0.016 14.9 4.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4048) DDE_Tnp_1_2 PF13586.1 CDI85240.1 - 0.051 13.7 0.5 0.14 12.3 0.3 1.7 1 0 0 1 1 1 0 Transposase DDE domain Prok-RING_2 PF14445.1 CDI85240.1 - 0.082 12.8 0.4 0.17 11.8 0.3 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 2 PAT1 PF09770.4 CDI85240.1 - 0.61 8.2 17.5 0.86 7.7 12.1 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Suf PF05843.9 CDI85240.1 - 1.9 8.1 6.5 2.6 7.7 4.5 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF2489 PF10675.4 CDI85240.1 - 3.4 7.3 13.7 6.5 6.4 3.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2489) TFIIA PF03153.8 CDI85240.1 - 5.2 6.8 16.1 6.7 6.4 11.1 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RAB3GAP2_N PF14655.1 CDI85240.1 - 5.4 5.9 10.4 0.93 8.4 2.9 2.0 1 1 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Neur_chan_memb PF02932.11 CDI85243.1 - 0.01 15.7 2.8 0.01 15.7 1.9 1.9 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region DUF1510 PF07423.6 CDI85243.1 - 0.69 9.2 16.4 0.046 13.0 7.0 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF1510) FAM60A PF15396.1 CDI85244.1 - 4.5 6.9 29.3 5.9 6.5 20.3 1.1 1 0 0 1 1 1 0 Protein Family FAM60A DUF2413 PF10310.4 CDI85244.1 - 5.7 5.6 38.3 7.1 5.3 26.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) UPF0016 PF01169.14 CDI85245.1 - 2.9e-07 30.5 14.3 2.9e-07 30.5 9.9 2.9 2 1 0 2 2 1 1 Uncharacterized protein family UPF0016 SAGA-Tad1 PF12767.2 CDI85245.1 - 0.0011 18.6 7.8 0.0015 18.2 5.4 1.2 1 0 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit Suf PF05843.9 CDI85245.1 - 0.0012 18.6 8.8 0.0015 18.2 6.1 1.1 1 0 0 1 1 1 1 Suppressor of forked protein (Suf) Neur_chan_memb PF02932.11 CDI85245.1 - 0.044 13.6 1.2 0.053 13.3 0.8 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Band_3_cyto PF07565.8 CDI85245.1 - 0.07 12.6 3.2 0.094 12.2 2.2 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain DUF775 PF05603.7 CDI85245.1 - 0.11 12.0 8.4 0.12 11.8 4.9 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF775) vMSA PF00695.14 CDI85245.1 - 0.16 11.1 7.0 0.22 10.7 4.8 1.2 1 0 0 1 1 1 0 Major surface antigen from hepadnavirus PAT1 PF09770.4 CDI85245.1 - 0.53 8.4 29.3 0.77 7.9 20.3 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF913 PF06025.7 CDI85245.1 - 0.8 8.3 4.3 1.1 7.8 3.0 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Peptidase_S49_N PF08496.5 CDI85245.1 - 0.83 9.4 12.1 1.7 8.3 8.4 1.5 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Pex16 PF08610.5 CDI85245.1 - 1.6 7.6 8.0 45 2.8 0.0 2.1 2 0 0 2 2 2 0 Peroxisomal membrane protein (Pex16) Ndc1_Nup PF09531.5 CDI85245.1 - 1.6 7.0 8.3 2.2 6.6 5.8 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF4544 PF15077.1 CDI85245.1 - 1.7 8.0 6.8 2.4 7.6 4.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4544) GAGA_bind PF06217.7 CDI85245.1 - 1.8 8.4 13.4 2.4 8.0 9.3 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family OATP PF03137.15 CDI85245.1 - 4.1 5.3 6.4 6.4 4.6 4.4 1.2 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family PBP1_TM PF14812.1 CDI85245.1 - 4.3 7.7 6.7 9.3 6.6 4.6 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DDRGK PF09756.4 CDI85245.1 - 5.6 6.3 17.3 9.1 5.6 12.0 1.2 1 0 0 1 1 1 0 DDRGK domain Paf1 PF03985.8 CDI85245.1 - 6.2 5.4 13.5 9.3 4.8 9.4 1.1 1 0 0 1 1 1 0 Paf1 DUF4366 PF14283.1 CDI85246.1 - 0.0035 16.7 4.4 0.0035 16.7 3.1 2.5 2 1 0 2 2 2 1 Domain of unknown function (DUF4366) DUF3357 PF11837.3 CDI85246.1 - 4.6 7.1 9.6 0.26 11.1 1.0 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF3357) CAF-1_p150 PF11600.3 CDI85248.1 - 0.0011 18.4 28.8 0.0018 17.6 20.0 1.3 1 0 0 1 1 1 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal TraT PF05818.7 CDI85248.1 - 0.013 14.9 12.4 0.015 14.7 8.6 1.1 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein Med15 PF09606.5 CDI85248.1 - 0.026 12.7 45.4 0.027 12.6 31.5 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Pox_H7 PF04787.7 CDI85248.1 - 0.07 12.9 2.6 0.087 12.6 1.8 1.3 1 0 0 1 1 1 0 Late protein H7 NARP1 PF12569.3 CDI85248.1 - 0.075 11.7 18.6 0.073 11.8 12.9 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 eIF-3_zeta PF05091.7 CDI85248.1 - 0.2 10.2 25.1 0.2 10.2 17.4 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) HemX PF04375.9 CDI85248.1 - 0.23 10.0 29.4 0.26 9.8 20.4 1.0 1 0 0 1 1 1 0 HemX Activator_LAG-3 PF11498.3 CDI85248.1 - 0.31 9.7 50.8 0.4 9.3 35.2 1.3 1 0 0 1 1 1 0 Transcriptional activator LAG-3 AAA_23 PF13476.1 CDI85248.1 - 0.32 11.3 18.9 0.31 11.3 13.1 1.1 1 0 0 1 1 1 0 AAA domain SprA-related PF12118.3 CDI85248.1 - 0.37 10.0 49.4 0.4 9.9 34.2 1.0 1 0 0 1 1 1 0 SprA-related family Peptidase_S15 PF02129.13 CDI85248.1 - 0.4 10.0 14.5 0.46 9.8 10.0 1.0 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) CmcH_NodU PF02543.10 CDI85248.1 - 0.46 9.5 10.3 0.49 9.4 7.2 1.0 1 0 0 1 1 1 0 Carbamoyltransferase PAT1 PF09770.4 CDI85248.1 - 0.58 8.3 37.6 0.57 8.3 26.1 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Serinc PF03348.10 CDI85248.1 - 0.72 8.5 19.6 0.77 8.4 13.6 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) PBP_sp32 PF07222.7 CDI85248.1 - 1.1 8.3 27.4 1.3 8.1 19.0 1.1 1 0 0 1 1 1 0 Proacrosin binding protein sp32 MRP-S26 PF14943.1 CDI85248.1 - 1.6 8.2 22.6 2 7.9 15.7 1.1 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 PcfK PF14058.1 CDI85248.1 - 1.7 8.8 23.7 1.9 8.6 16.5 1.2 1 0 0 1 1 1 0 PcfK-like protein PBP1_TM PF14812.1 CDI85248.1 - 1.7 8.9 9.5 2.4 8.5 6.6 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF4011 PF13195.1 CDI85248.1 - 2.3 8.2 11.8 2.5 8.0 8.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4011) Zip PF02535.17 CDI85248.1 - 2.6 6.9 10.3 2.6 6.9 7.2 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter DUF2098 PF09871.4 CDI85248.1 - 3.4 7.6 8.6 5.3 7.0 5.9 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2098) DOR PF14839.1 CDI85248.1 - 3.5 7.3 32.7 4.1 7.1 22.7 1.0 1 0 0 1 1 1 0 DOR family FLO_LFY PF01698.11 CDI85248.1 - 4.1 6.1 20.7 4.3 6.0 14.3 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein Borrelia_P83 PF05262.6 CDI85248.1 - 4.4 5.4 21.0 4.2 5.5 14.6 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein FPN1 PF06963.7 CDI85248.1 - 5.2 5.3 7.2 7.1 4.8 5.0 1.3 1 0 0 1 1 1 0 Ferroportin1 (FPN1) RR_TM4-6 PF06459.7 CDI85248.1 - 5.4 6.8 21.1 6 6.6 14.6 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Folate_carrier PF01770.13 CDI85248.1 - 5.5 5.3 10.3 5.4 5.4 7.1 1.2 1 0 0 1 1 1 0 Reduced folate carrier Ycf1 PF05758.7 CDI85248.1 - 5.6 4.5 19.2 5.2 4.6 13.3 1.0 1 0 0 1 1 1 0 Ycf1 OATP PF03137.15 CDI85248.1 - 5.6 4.8 12.0 5.7 4.8 8.3 1.2 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family FimP PF09766.4 CDI85248.1 - 6.2 5.7 32.2 8.1 5.3 22.3 1.3 1 0 0 1 1 1 0 Fms-interacting protein Raftlin PF15250.1 CDI85248.1 - 6.7 5.1 21.5 7.1 5.0 14.9 1.1 1 0 0 1 1 1 0 Raftlin Apt1 PF10351.4 CDI85248.1 - 6.9 5.4 19.4 8.7 5.0 13.5 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain BTV_NS2 PF04514.7 CDI85248.1 - 8.7 5.1 16.8 9.8 4.9 11.6 1.2 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Paf1 PF03985.8 CDI85248.1 - 9 4.9 25.6 10 4.7 17.8 1.1 1 0 0 1 1 1 0 Paf1 APG6 PF04111.7 CDI85248.1 - 9.5 5.1 25.1 10 5.0 17.4 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 NPR3 PF03666.8 CDI85249.1 - 1.2 7.6 11.7 1.8 6.9 8.1 1.4 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF4551 PF15087.1 CDI85249.1 - 2.3 6.4 10.9 2.3 6.4 7.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Apt1 PF10351.4 CDI85249.1 - 9.4 4.9 22.2 16 4.1 15.4 1.4 1 0 0 1 1 1 0 Golgi-body localisation protein domain Band_3_cyto PF07565.8 CDI85250.1 - 0.014 14.8 4.3 0.014 14.8 3.0 2.1 2 0 0 2 2 2 0 Band 3 cytoplasmic domain DUF819 PF05684.7 CDI85250.1 - 0.033 13.0 0.0 0.037 12.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF819) DUF3464 PF11947.3 CDI85250.1 - 0.18 11.2 13.6 0.87 9.0 0.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3464) FimP PF09766.4 CDI85250.1 - 0.4 9.6 27.2 0.019 14.0 8.0 2.1 2 0 0 2 2 2 0 Fms-interacting protein DUF572 PF04502.8 CDI85250.1 - 0.68 9.0 16.9 0.93 8.6 11.7 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) AIF_C PF14721.1 CDI85250.1 - 1.4 9.1 9.3 0.53 10.5 1.5 2.2 2 0 0 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term BAF1_ABF1 PF04684.8 CDI85250.1 - 1.4 7.7 49.3 0.24 10.1 14.2 2.0 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor DUF775 PF05603.7 CDI85250.1 - 1.6 8.2 19.1 0.065 12.7 4.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF775) FAM176 PF14851.1 CDI85250.1 - 1.8 8.2 7.7 0.4 10.3 0.8 2.1 2 0 0 2 2 2 0 FAM176 family Agouti PF05039.7 CDI85250.1 - 1.8 8.9 12.7 1.1 9.6 3.2 2.2 2 0 0 2 2 2 0 Agouti protein OATP PF03137.15 CDI85250.1 - 2.8 5.8 15.1 0.34 8.8 1.6 2.0 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family DUF3306 PF11748.3 CDI85250.1 - 4.7 7.9 16.4 12 6.5 5.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3306) DUF1764 PF08576.5 CDI85250.1 - 5.4 7.8 20.7 5.3 7.8 6.9 2.2 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF1764) Peptidase_U57 PF05582.7 CDI85250.1 - 6.1 5.7 15.3 2.8 6.8 4.6 2.0 2 0 0 2 2 2 0 YabG peptidase U57 DUF4207 PF13904.1 CDI85250.1 - 8.5 5.6 36.2 2.1 7.6 4.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4207) Stig1 PF04885.8 CDI85250.1 - 8.6 6.5 8.3 11 6.2 1.1 2.1 2 0 0 2 2 2 0 Stigma-specific protein, Stig1 Spore_coat_CotO PF14153.1 CDI85250.1 - 8.6 5.7 23.4 1.5 8.2 6.7 2.1 2 0 0 2 2 2 0 Spore coat protein CotO DUF3883 PF13020.1 CDI85252.1 - 0.15 11.8 0.0 0.38 10.5 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3883) SAPS PF04499.10 CDI85252.1 - 0.96 8.0 0.0 0.048 12.2 3.8 10.8 7 3 0 7 7 7 0 SIT4 phosphatase-associated protein Clathrin PF00637.15 CDI85253.1 - 0.063 12.8 0.0 0.076 12.6 0.0 1.2 1 0 0 1 1 1 0 Region in Clathrin and VPS HABP4_PAI-RBP1 PF04774.10 CDI85254.1 - 0.038 14.5 2.7 0.056 13.9 1.9 1.3 1 0 0 1 1 1 0 Hyaluronan / mRNA binding family DUF4139 PF13598.1 CDI85254.1 - 1 8.6 8.1 1.4 8.1 5.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4139) DUF4349 PF14257.1 CDI85254.1 - 4.1 6.5 15.4 0.49 9.5 8.1 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4349) DUF3138 PF11336.3 CDI85254.1 - 5 5.1 10.6 6.1 4.9 7.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) MSP1_C PF07462.6 CDI85254.1 - 6.2 5.0 7.8 7.7 4.7 5.4 1.1 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus SR-25 PF10500.4 CDI85255.1 - 0.14 11.5 10.7 0.26 10.7 7.4 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein TFIIA PF03153.8 CDI85255.1 - 0.5 10.1 7.0 0.62 9.8 4.8 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4593 PF15263.1 CDI85258.1 - 0.12 12.2 2.8 0.28 11.0 1.8 1.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4593) DivIC PF04977.10 CDI85259.1 - 1.3 8.5 7.8 2.8 7.4 5.4 1.4 1 0 0 1 1 1 0 Septum formation initiator BRF1 PF07741.8 CDI85261.1 - 0.0057 16.8 1.9 0.0057 16.8 1.3 2.3 3 0 0 3 3 3 1 Brf1-like TBP-binding domain LcrG PF07216.7 CDI85261.1 - 0.038 13.9 1.6 0.14 12.2 1.1 1.9 1 0 0 1 1 1 0 LcrG protein PEX11 PF05648.9 CDI85261.1 - 0.06 12.5 3.3 0.1 11.8 2.3 1.3 1 0 0 1 1 1 0 Peroxisomal biogenesis factor 11 (PEX11) APC_CDC26 PF10471.4 CDI85261.1 - 0.25 12.1 12.6 0.22 12.2 6.5 2.6 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit 1 CAF-1_p150 PF11600.3 CDI85262.1 - 0.34 10.2 65.9 0.41 9.9 45.7 1.0 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal SR-25 PF10500.4 CDI85262.1 - 2.8 7.3 64.3 0.036 13.5 24.8 2.1 1 1 1 2 2 2 0 Nuclear RNA-splicing-associated protein VIT1 PF01988.14 CDI85263.1 - 0.026 14.0 5.3 0.036 13.5 3.7 1.3 1 0 0 1 1 1 0 VIT family Rabaptin PF03528.10 CDI85263.1 - 0.075 12.9 8.4 0.13 12.2 5.8 1.3 1 0 0 1 1 1 0 Rabaptin Uso1_p115_C PF04871.8 CDI85263.1 - 0.51 10.2 10.6 0.16 11.8 4.5 1.9 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region Nop14 PF04147.7 CDI85263.1 - 0.62 7.9 7.3 0.74 7.6 5.1 1.0 1 0 0 1 1 1 0 Nop14-like family Spore_YhcN_YlaJ PF09580.5 CDI85263.1 - 0.73 9.9 5.2 0.83 9.7 3.6 1.1 1 0 0 1 1 1 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) Hexokinase_2 PF03727.11 CDI85263.1 - 1.8 7.6 6.8 2.1 7.4 4.7 1.0 1 0 0 1 1 1 0 Hexokinase CAF-1_p150 PF11600.3 CDI85265.1 - 0.00041 19.8 19.2 0.00041 19.8 13.3 3.7 3 2 1 4 4 4 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal Utp14 PF04615.8 CDI85265.1 - 3.8 5.5 77.5 0.72 7.9 15.4 2.2 2 0 0 2 2 2 0 Utp14 protein SR-25 PF10500.4 CDI85266.1 - 0.0038 16.7 23.9 0.0038 16.7 16.6 1.5 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein DUF605 PF04652.11 CDI85266.1 - 4.4 6.6 28.5 0.058 12.7 13.8 2.0 2 0 0 2 2 2 0 Vta1 like DUF2029 PF09594.5 CDI85267.1 - 7.6 5.9 16.9 3.1 7.2 6.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2029) Med15 PF09606.5 CDI85268.1 - 0.0021 16.3 23.3 0.0023 16.2 16.2 1.1 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal FimP PF09766.4 CDI85268.1 - 0.0023 17.0 6.8 0.0023 17.0 4.7 1.1 1 0 0 1 1 1 1 Fms-interacting protein Suf PF05843.9 CDI85268.1 - 0.0065 16.2 5.6 0.0065 16.2 3.9 1.1 1 0 0 1 1 1 1 Suppressor of forked protein (Suf) PAT1 PF09770.4 CDI85268.1 - 0.0071 14.6 13.8 0.0057 14.9 9.5 1.1 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 DUF788 PF05620.6 CDI85268.1 - 0.012 15.5 3.2 0.016 15.0 2.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF788) Zip PF02535.17 CDI85268.1 - 0.012 14.6 0.6 0.013 14.5 0.4 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter eIF_4EBP PF05456.6 CDI85268.1 - 0.025 14.2 2.1 0.041 13.5 1.4 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) CD20 PF04103.10 CDI85268.1 - 0.028 14.3 0.5 0.039 13.8 0.3 1.3 1 0 0 1 1 1 0 CD20-like family Bac_luciferase PF00296.15 CDI85268.1 - 0.035 13.2 1.5 0.04 13.0 1.0 1.0 1 0 0 1 1 1 0 Luciferase-like monooxygenase Erv26 PF04148.8 CDI85268.1 - 0.057 12.7 0.4 0.07 12.4 0.3 1.1 1 0 0 1 1 1 0 Transmembrane adaptor Erv26 FHIPEP PF00771.15 CDI85268.1 - 0.25 9.6 3.4 0.26 9.5 2.3 1.1 1 0 0 1 1 1 0 FHIPEP family EphA2_TM PF14575.1 CDI85268.1 - 0.35 11.3 1.7 0.62 10.4 1.2 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain RAP1 PF07218.6 CDI85269.1 - 1.8 6.5 9.9 2.2 6.2 6.8 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) CAF-1_p150 PF11600.3 CDI85269.1 - 3.5 6.9 57.8 0.0092 15.3 26.1 2.0 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal FUSC_2 PF13515.1 CDI85270.1 - 0.014 15.3 0.7 0.13 12.1 0.1 2.4 2 1 0 2 2 2 0 Fusaric acid resistance protein-like SR-25 PF10500.4 CDI85270.1 - 0.015 14.8 23.1 0.29 10.5 2.1 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Fungal_trans_2 PF11951.3 CDI85270.1 - 0.019 13.6 1.6 0.022 13.3 1.1 1.3 1 0 0 1 1 1 0 Fungal specific transcription factor domain Macoilin PF09726.4 CDI85270.1 - 0.049 11.9 10.4 0.058 11.6 7.2 1.1 1 0 0 1 1 1 0 Transmembrane protein TraG-D_C PF12696.2 CDI85270.1 - 0.05 13.4 1.9 5.8 6.7 0.2 2.2 2 0 0 2 2 2 0 TraM recognition site of TraD and TraG DUF1183 PF06682.7 CDI85270.1 - 0.06 12.9 7.4 0.09 12.3 5.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) FSA_C PF10479.4 CDI85270.1 - 0.065 11.3 0.2 0.083 10.9 0.1 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Sporozoite_P67 PF05642.6 CDI85270.1 - 0.39 8.5 6.8 0.51 8.1 4.7 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Scm3 PF10384.4 CDI85270.1 - 0.67 9.4 2.6 1.1 8.8 1.8 1.3 1 0 0 1 1 1 0 Centromere protein Scm3 Ashwin PF15323.1 CDI85270.1 - 9.8 6.1 9.1 27 4.6 6.3 1.7 1 1 0 1 1 1 0 Developmental protein TRAP_alpha PF03896.11 CDI85271.1 - 0.004 16.2 9.9 0.004 16.2 6.8 2.1 1 1 1 2 2 2 1 Translocon-associated protein (TRAP), alpha subunit Neur_chan_memb PF02932.11 CDI85271.1 - 0.0085 15.9 32.6 0.012 15.5 22.6 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Ycf1 PF05758.7 CDI85271.1 - 0.054 11.2 43.1 0.084 10.5 29.8 1.3 1 0 0 1 1 1 0 Ycf1 Hid1 PF12722.2 CDI85271.1 - 0.16 9.5 49.0 0.19 9.3 34.0 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF1510 PF07423.6 CDI85271.1 - 1.3 8.3 56.7 28 3.9 39.3 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1510) Nha1_C PF08619.5 CDI85271.1 - 2.1 7.5 46.2 2.7 7.1 32.0 1.1 1 0 0 1 1 1 0 Alkali metal cation/H+ antiporter Nha1 C terminus DUF4010 PF13194.1 CDI85271.1 - 4.9 6.3 12.8 10 5.3 8.8 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4010) Nop53 PF07767.6 CDI85271.1 - 8.8 5.1 60.3 15 4.4 41.8 1.3 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Med15 PF09606.5 CDI85272.1 - 6.9 4.7 115.0 7.2 4.6 79.7 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal PAT1 PF09770.4 CDI85272.1 - 9.1 4.3 106.8 11 4.1 74.1 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 PAT1 PF09770.4 CDI85273.1 - 0.002 16.4 47.1 0.0023 16.2 32.7 1.1 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 DUF2126 PF09899.4 CDI85273.1 - 0.041 11.9 7.2 0.053 11.5 5.0 1.3 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) Herpes_LMP2 PF07415.6 CDI85273.1 - 0.064 11.8 3.7 0.083 11.4 2.5 1.2 1 0 0 1 1 1 0 Gammaherpesvirus latent membrane protein (LMP2) protein TFIIA PF03153.8 CDI85273.1 - 0.083 12.7 34.5 0.098 12.5 23.9 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Raftlin PF15250.1 CDI85273.1 - 0.14 10.6 16.0 0.16 10.4 11.1 1.1 1 0 0 1 1 1 0 Raftlin GAGA_bind PF06217.7 CDI85273.1 - 0.16 11.8 15.6 0.2 11.6 10.8 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family SOBP PF15279.1 CDI85273.1 - 0.2 12.0 21.7 0.25 11.6 15.0 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein Ycf1 PF05758.7 CDI85273.1 - 0.2 9.3 15.4 0.23 9.1 10.7 1.0 1 0 0 1 1 1 0 Ycf1 DUF1510 PF07423.6 CDI85273.1 - 0.27 10.5 18.9 0.52 9.6 13.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DUF4045 PF13254.1 CDI85273.1 - 0.29 10.3 15.7 0.35 10.0 10.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Band_3_cyto PF07565.8 CDI85273.1 - 0.3 10.5 18.9 0.44 10.0 13.1 1.3 1 0 0 1 1 1 0 Band 3 cytoplasmic domain MoeZ_MoeB PF05237.8 CDI85273.1 - 0.35 10.4 4.0 1.6 8.3 2.8 2.2 1 1 0 1 1 1 0 MoeZ/MoeB domain Herpes_UL87 PF03043.9 CDI85273.1 - 0.36 9.1 8.2 0.35 9.2 5.7 1.1 1 0 0 1 1 1 0 Herpesvirus UL87 family Neur_chan_memb PF02932.11 CDI85273.1 - 0.59 9.9 13.9 0.83 9.4 9.7 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region V_ATPase_I PF01496.14 CDI85273.1 - 0.74 7.6 6.5 0.78 7.5 4.5 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family LMBR1 PF04791.11 CDI85273.1 - 0.82 8.1 5.8 0.96 7.9 4.0 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Asp-B-Hydro_N PF05279.6 CDI85273.1 - 0.94 9.2 10.1 1.2 8.8 7.0 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region DHHW PF14286.1 CDI85273.1 - 1 8.5 9.1 1.3 8.2 6.3 1.3 1 0 0 1 1 1 0 DHHW protein BTV_NS2 PF04514.7 CDI85273.1 - 1.3 7.8 12.5 1.5 7.5 8.7 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Dicty_REP PF05086.7 CDI85273.1 - 1.8 6.1 11.6 2 6.0 8.0 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein HCO3_cotransp PF00955.16 CDI85273.1 - 1.9 7.0 5.2 3.1 6.3 3.6 1.2 1 0 0 1 1 1 0 HCO3- transporter family Herpes_DNAp_acc PF04929.7 CDI85273.1 - 2.2 7.1 19.1 3.6 6.4 13.2 1.3 1 0 0 1 1 1 0 Herpes DNA replication accessory factor SID-1_RNA_chan PF13965.1 CDI85273.1 - 2.9 5.9 6.4 4.2 5.4 4.5 1.4 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 MDFI PF15316.1 CDI85273.1 - 3 7.8 19.2 4.6 7.1 12.9 1.5 1 1 0 1 1 1 0 MyoD family inhibitor Paramyxo_ncap PF00973.14 CDI85273.1 - 3.2 6.3 16.0 3.7 6.1 11.1 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein HlyD_2 PF12700.2 CDI85273.1 - 3.9 6.5 17.2 5.7 6.0 11.9 1.2 1 0 0 1 1 1 0 HlyD family secretion protein Hid1 PF12722.2 CDI85273.1 - 4 4.9 20.8 4.5 4.8 14.4 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Cellulose_synt PF03552.9 CDI85273.1 - 4.2 5.5 5.4 5.2 5.2 3.7 1.2 1 0 0 1 1 1 0 Cellulose synthase SPX PF03105.14 CDI85273.1 - 4.4 6.9 20.5 6.2 6.5 14.2 1.2 1 0 0 1 1 1 0 SPX domain GNT-I PF03071.10 CDI85273.1 - 4.7 5.6 12.0 6.7 5.1 8.3 1.3 1 0 0 1 1 1 0 GNT-I family CIAPIN1 PF05093.8 CDI85273.1 - 6.3 6.9 18.8 0.3 11.1 5.6 2.3 2 0 0 2 2 2 0 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis DUF4512 PF14975.1 CDI85273.1 - 7.4 7.4 11.3 11 6.9 7.3 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4512) Zip PF02535.17 CDI85274.1 - 0.00057 18.9 14.4 0.00076 18.5 10.0 1.4 1 0 0 1 1 1 1 ZIP Zinc transporter CDC45 PF02724.9 CDI85274.1 - 0.0065 14.5 3.5 0.0067 14.5 2.5 1.1 1 0 0 1 1 1 1 CDC45-like protein PAT1 PF09770.4 CDI85274.1 - 0.0068 14.7 31.8 0.0069 14.7 22.0 1.0 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 Spore_coat_CotO PF14153.1 CDI85274.1 - 0.012 15.1 8.8 0.014 14.8 6.1 1.3 1 0 0 1 1 1 0 Spore coat protein CotO Exonuc_VII_L PF02601.10 CDI85274.1 - 0.012 14.8 7.5 0.014 14.5 5.2 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit SprA-related PF12118.3 CDI85274.1 - 0.071 12.4 34.9 0.094 12.0 24.2 1.2 1 0 0 1 1 1 0 SprA-related family SelP_N PF04592.9 CDI85274.1 - 0.079 12.3 26.5 0.017 14.5 16.0 1.8 2 0 0 2 2 2 0 Selenoprotein P, N terminal region Raftlin PF15250.1 CDI85274.1 - 0.092 11.2 7.8 0.097 11.1 5.4 1.1 1 0 0 1 1 1 0 Raftlin TFIIA PF03153.8 CDI85274.1 - 0.12 12.2 29.9 0.13 12.1 20.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DRY_EERY PF09750.4 CDI85274.1 - 0.18 11.9 11.1 0.38 10.8 7.7 1.5 1 0 0 1 1 1 0 Alternative splicing regulator Ycf1 PF05758.7 CDI85274.1 - 0.18 9.5 4.5 0.17 9.5 3.1 1.0 1 0 0 1 1 1 0 Ycf1 eIF-3_zeta PF05091.7 CDI85274.1 - 0.33 9.5 8.3 0.36 9.3 5.8 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) FHIPEP PF00771.15 CDI85274.1 - 0.42 8.8 1.7 0.56 8.4 1.2 1.2 1 0 0 1 1 1 0 FHIPEP family RR_TM4-6 PF06459.7 CDI85274.1 - 0.55 10.0 12.2 0.78 9.5 8.5 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF605 PF04652.11 CDI85274.1 - 0.69 9.2 28.4 0.77 9.0 19.7 1.1 1 0 0 1 1 1 0 Vta1 like Hid1 PF12722.2 CDI85274.1 - 0.8 7.3 10.2 0.79 7.3 7.0 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Neur_chan_memb PF02932.11 CDI85274.1 - 0.91 9.3 11.5 1 9.2 8.0 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Pox_Ag35 PF03286.9 CDI85274.1 - 1 8.8 8.3 1.4 8.3 5.8 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DUF1387 PF07139.6 CDI85274.1 - 1.2 8.7 14.0 1.6 8.2 9.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) Med15 PF09606.5 CDI85274.1 - 1.5 6.8 42.5 1.9 6.6 29.4 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal OATP PF03137.15 CDI85274.1 - 1.9 6.4 5.0 2.5 6.0 3.5 1.4 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family DUF4045 PF13254.1 CDI85274.1 - 2 7.5 18.3 1.8 7.7 11.7 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4045) FliP PF00813.15 CDI85274.1 - 2.4 7.8 4.3 3.4 7.3 2.9 1.2 1 0 0 1 1 1 0 FliP family Presenilin PF01080.12 CDI85274.1 - 2.9 6.6 10.7 3.8 6.2 7.4 1.3 1 0 0 1 1 1 0 Presenilin Otopetrin PF03189.8 CDI85274.1 - 3 6.7 7.3 3.4 6.5 5.1 1.1 1 0 0 1 1 1 0 Otopetrin GIDE PF12483.3 CDI85274.1 - 3 7.1 9.2 0.065 12.6 1.0 1.9 1 1 1 2 2 2 0 E3 Ubiquitin ligase NicO PF03824.11 CDI85274.1 - 3.5 6.8 13.0 4.9 6.3 9.0 1.2 1 0 0 1 1 1 0 High-affinity nickel-transport protein Band_3_cyto PF07565.8 CDI85274.1 - 4.3 6.7 13.1 5.9 6.3 9.1 1.3 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Macoilin PF09726.4 CDI85274.1 - 4.3 5.4 22.8 2.4 6.3 14.8 1.3 1 1 0 1 1 1 0 Transmembrane protein DUF1510 PF07423.6 CDI85274.1 - 4.6 6.5 12.2 6.3 6.0 8.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) HemX PF04375.9 CDI85274.1 - 6.6 5.2 24.1 9.9 4.6 16.7 1.2 1 0 0 1 1 1 0 HemX Med5 PF08689.5 CDI85274.1 - 7.4 4.1 9.6 7.9 4.0 6.7 1.1 1 0 0 1 1 1 0 Mediator complex subunit Med5 DUF3984 PF13136.1 CDI85274.1 - 8 5.5 25.4 4 6.5 16.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3984) BTV_NS2 PF04514.7 CDI85274.1 - 9.6 4.9 10.2 13 4.5 7.1 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 MIP-T3 PF10243.4 CDI85275.1 - 5 5.4 65.8 7.2 4.9 45.6 1.2 1 1 0 1 1 1 0 Microtubule-binding protein MIP-T3 ETRAMP PF09716.5 CDI85276.1 - 0.03 14.2 0.5 0.03 14.2 0.3 2.7 1 1 1 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) DUF4179 PF13786.1 CDI85276.1 - 3.5 7.9 4.6 0.7 10.1 0.5 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4179) IncA PF04156.9 CDI85277.1 - 4.5e-06 26.3 12.3 4.5e-06 26.3 8.5 2.0 1 1 0 2 2 1 1 IncA protein Med15 PF09606.5 CDI85277.1 - 0.00083 17.7 56.7 0.0011 17.3 39.3 1.1 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal TraT PF05818.7 CDI85277.1 - 0.0057 16.1 12.2 0.0057 16.1 8.5 2.1 2 0 0 2 2 2 1 Enterobacterial TraT complement resistance protein zf-DHHC PF01529.15 CDI85277.1 - 0.0075 15.6 5.3 0.16 11.3 0.5 2.1 2 0 0 2 2 2 2 DHHC palmitoyltransferase DUF2244 PF10003.4 CDI85277.1 - 0.0093 15.3 1.9 0.018 14.3 1.3 1.5 1 0 0 1 1 1 1 Integral membrane protein (DUF2244) eIF-3_zeta PF05091.7 CDI85277.1 - 0.017 13.7 19.4 0.021 13.4 13.4 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) SR-25 PF10500.4 CDI85277.1 - 0.034 13.6 9.6 0.62 9.4 0.2 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein SPX PF03105.14 CDI85277.1 - 0.2 11.3 9.9 0.28 10.9 6.9 1.2 1 0 0 1 1 1 0 SPX domain Activator_LAG-3 PF11498.3 CDI85277.1 - 0.21 10.2 57.5 0.25 10.0 39.9 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 FimP PF09766.4 CDI85277.1 - 0.3 10.1 28.8 0.8 8.6 7.9 2.0 2 0 0 2 2 2 0 Fms-interacting protein TFIIA PF03153.8 CDI85277.1 - 0.35 10.7 39.4 0.53 10.1 27.3 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Eapp_C PF10238.4 CDI85277.1 - 0.54 10.1 12.0 3.2 7.6 0.5 2.1 2 0 0 2 2 2 0 E2F-associated phosphoprotein MRP-S26 PF14943.1 CDI85277.1 - 0.61 9.6 18.3 1.1 8.8 2.5 2.1 2 0 0 2 2 2 0 Mitochondrial ribosome subunit S26 Neur_chan_memb PF02932.11 CDI85277.1 - 0.88 9.4 9.7 1.2 8.9 6.7 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF4207 PF13904.1 CDI85277.1 - 0.94 8.8 36.1 0.06 12.7 7.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4207) DUF1764 PF08576.5 CDI85277.1 - 1.1 10.0 18.0 2 9.2 3.0 2.2 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF1764) Sporozoite_P67 PF05642.6 CDI85277.1 - 1.3 6.8 9.2 1.6 6.5 6.4 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen SAGA-Tad1 PF12767.2 CDI85277.1 - 1.6 8.2 17.8 2.5 7.7 12.3 1.3 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit TT_ORF2 PF02957.10 CDI85277.1 - 1.8 9.3 13.4 3.2 8.4 1.2 2.3 2 0 0 2 2 2 0 TT viral ORF2 Anoctamin PF04547.7 CDI85277.1 - 1.9 7.0 10.9 2.6 6.6 7.6 1.2 1 0 0 1 1 1 0 Calcium-activated chloride channel CD20 PF04103.10 CDI85277.1 - 2 8.3 11.1 0.25 11.2 0.6 2.3 1 1 1 2 2 2 0 CD20-like family DcuC PF03606.10 CDI85277.1 - 2.3 6.3 16.9 3.2 5.8 7.8 2.0 2 0 0 2 2 2 0 C4-dicarboxylate anaerobic carrier PAT1 PF09770.4 CDI85277.1 - 2.4 6.2 44.4 2.9 5.9 30.8 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Glyco_hydro_1 PF00232.13 CDI85277.1 - 2.8 6.0 11.7 3.5 5.7 8.1 1.0 1 0 0 1 1 1 0 Glycosyl hydrolase family 1 Afi1 PF07792.7 CDI85277.1 - 5 7.1 14.2 11 6.0 9.9 1.5 1 1 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking DUF2149 PF09919.4 CDI85277.1 - 5.8 7.0 11.8 7.3 6.7 1.3 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2149) Herpes_glycop PF01528.11 CDI85277.1 - 7.9 5.0 17.3 3.8 6.0 1.0 2.1 2 0 0 2 2 2 0 Herpesvirus glycoprotein M ARF7EP_C PF14949.1 CDI85277.1 - 8.4 6.8 13.2 5.3 7.5 0.9 2.2 2 0 0 2 2 2 0 ARF7 effector protein C-terminus Nha1_C PF08619.5 CDI85278.1 - 0.41 9.8 22.0 0.44 9.7 15.2 1.0 1 0 0 1 1 1 0 Alkali metal cation/H+ antiporter Nha1 C terminus MRP-S31 PF15433.1 CDI85278.1 - 0.59 9.5 19.3 0.71 9.2 13.3 1.1 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 Pex14_N PF04695.8 CDI85278.1 - 0.6 10.1 21.7 0.67 10.0 15.1 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Raftlin PF15250.1 CDI85278.1 - 0.74 8.2 19.2 0.74 8.2 13.3 1.0 1 0 0 1 1 1 0 Raftlin Gti1_Pac2 PF09729.4 CDI85278.1 - 1.2 9.0 16.3 1.4 8.7 11.3 1.1 1 0 0 1 1 1 0 Gti1/Pac2 family FimP PF09766.4 CDI85278.1 - 1.2 8.1 31.9 1.5 7.8 22.1 1.2 1 0 0 1 1 1 0 Fms-interacting protein TCP PF03634.8 CDI85278.1 - 1.8 8.9 21.0 2 8.7 14.5 1.1 1 0 0 1 1 1 0 TCP family transcription factor PAT1 PF09770.4 CDI85278.1 - 2.2 6.4 37.2 2.1 6.4 25.8 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 FLO_LFY PF01698.11 CDI85278.1 - 2.3 6.9 20.3 2.5 6.8 14.1 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein HGTP_anticodon2 PF12745.2 CDI85278.1 - 2.4 7.2 20.5 2.6 7.1 14.2 1.0 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs YqfQ PF14181.1 CDI85278.1 - 2.4 8.1 22.5 2.8 7.9 15.6 1.2 1 0 0 1 1 1 0 YqfQ-like protein DUF1764 PF08576.5 CDI85278.1 - 3.5 8.4 21.3 4.3 8.1 14.7 1.2 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) ARF7EP_C PF14949.1 CDI85278.1 - 3.5 8.0 15.2 4.4 7.7 10.5 1.3 1 0 0 1 1 1 0 ARF7 effector protein C-terminus DUF966 PF06136.8 CDI85278.1 - 4 6.7 18.0 4 6.7 12.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF966) FAM176 PF14851.1 CDI85278.1 - 5.9 6.5 14.6 7.2 6.2 10.1 1.2 1 0 0 1 1 1 0 FAM176 family Tim54 PF11711.3 CDI85278.1 - 6.3 5.2 18.5 7.1 5.1 12.8 1.0 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Med19 PF10278.4 CDI85278.1 - 6.3 6.4 16.7 6.9 6.3 11.5 1.0 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 DUF1645 PF07816.6 CDI85278.1 - 6.9 7.0 11.5 9.9 6.5 8.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1645) FYDLN_acid PF09538.5 CDI85278.1 - 7.1 7.2 13.7 8.7 6.9 9.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) RIC3 PF15361.1 CDI85278.1 - 7.4 6.7 16.1 8.4 6.6 11.1 1.3 1 0 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 DDHD PF02862.12 CDI85278.1 - 8.1 6.1 20.9 8.9 6.0 14.5 1.1 1 0 0 1 1 1 0 DDHD domain BORG_CEP PF14957.1 CDI85278.1 - 8.2 7.3 14.1 10 7.0 9.7 1.2 1 0 0 1 1 1 0 Cdc42 effector SeqA PF03925.8 CDI85278.1 - 8.8 5.9 16.4 9.9 5.8 11.4 1.1 1 0 0 1 1 1 0 SeqA protein DUF913 PF06025.7 CDI85278.1 - 8.8 4.9 11.3 8.3 5.0 7.8 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) GAGA_bind PF06217.7 CDI85278.1 - 9.3 6.1 17.5 9.6 6.0 12.1 1.0 1 0 0 1 1 1 0 GAGA binding protein-like family TFIIA PF03153.8 CDI85278.1 - 9.3 6.0 33.5 10 5.8 23.2 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Paf1 PF03985.8 CDI85278.1 - 9.4 4.8 30.9 11 4.6 21.4 1.0 1 0 0 1 1 1 0 Paf1 F-protein PF00469.15 CDI85278.1 - 9.8 5.4 17.5 9.8 5.4 12.1 1.1 1 0 0 1 1 1 0 Negative factor, (F-Protein) or Nef DUF4045 PF13254.1 CDI85278.1 - 9.9 5.3 18.5 11 5.2 12.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) START PF01852.14 CDI85279.1 - 3.7e-08 32.9 0.0 0.00036 19.9 0.0 2.3 2 0 0 2 2 2 2 START domain DUF3157 PF11355.3 CDI85279.1 - 0.29 10.4 5.6 0.11 11.7 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3157) PsbQ PF05757.6 CDI85279.1 - 3.7 6.9 14.8 0.59 9.5 3.2 2.3 2 0 0 2 2 2 0 Oxygen evolving enhancer protein 3 (PsbQ) ASFV_J13L PF05568.6 CDI85282.1 - 0.15 11.5 8.3 0.23 10.9 5.7 1.3 1 0 0 1 1 1 0 African swine fever virus J13L protein FUSC PF04632.7 CDI85282.1 - 1.1 7.6 16.4 1.3 7.3 11.4 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family SPX PF03105.14 CDI85282.1 - 1.2 8.9 10.4 1.1 8.9 7.2 1.1 1 0 0 1 1 1 0 SPX domain PAT1 PF09770.4 CDI85282.1 - 3.4 5.7 34.1 3.3 5.8 23.7 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 MIP-T3 PF10243.4 CDI85283.1 - 0.019 13.4 50.1 0.023 13.1 34.7 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 SOBP PF15279.1 CDI85283.1 - 0.23 11.8 17.5 0.27 11.6 12.1 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein GAGA_bind PF06217.7 CDI85283.1 - 2.5 7.9 35.7 3.3 7.5 4.4 2.0 2 0 0 2 2 2 0 GAGA binding protein-like family DUF1168 PF06658.7 CDI85283.1 - 8.3 5.9 49.2 1.5 8.3 22.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1168) Peptidase_M16_C PF05193.16 CDI85286.1 - 3.6e-26 91.9 0.2 1.2e-09 38.0 0.1 3.7 3 1 0 3 3 3 3 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 CDI85286.1 - 2.1e-15 56.7 0.6 2.3e-13 50.1 0.7 3.0 2 1 0 2 2 2 1 Insulinase (Peptidase family M16) PEP-utilisers_N PF05524.8 CDI85286.1 - 1.3 8.8 9.1 11 5.8 0.1 3.9 3 0 0 3 3 3 0 PEP-utilising enzyme, N-terminal ALAD PF00490.16 CDI85287.1 - 2.6e-136 453.7 0.0 3.2e-136 453.4 0.0 1.1 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase Nop14 PF04147.7 CDI85287.1 - 0.04 11.8 5.7 0.053 11.4 3.9 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 CDI85287.1 - 0.9 7.4 4.1 1.3 7.0 2.8 1.1 1 0 0 1 1 1 0 CDC45-like protein AP2 PF00847.15 CDI85288.1 - 0.00013 22.0 0.1 0.00034 20.7 0.0 1.7 1 0 0 1 1 1 1 AP2 domain Methyltransf_18 PF12847.2 CDI85289.1 - 5.8e-10 39.7 0.0 1.6e-09 38.2 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CDI85289.1 - 5.5e-09 35.7 0.0 4.5e-06 26.3 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.1 CDI85289.1 - 1.4e-07 31.3 0.0 6.2e-07 29.2 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CDI85289.1 - 4e-07 30.4 0.0 5.7e-06 26.7 0.0 2.5 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 CDI85289.1 - 2.1e-06 28.0 0.2 6.1e-06 26.5 0.1 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 CDI85289.1 - 2.9e-05 24.0 0.0 0.00012 22.0 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 CDI85289.1 - 0.00022 21.6 0.1 0.001 19.4 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 CDI85289.1 - 0.017 14.5 0.0 0.028 13.8 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain PrmA PF06325.8 CDI85289.1 - 0.074 12.1 0.0 0.14 11.2 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Corona_nucleoca PF00937.13 CDI85289.1 - 0.19 10.6 16.7 0.063 12.2 7.2 2.1 2 0 0 2 2 2 0 Coronavirus nucleocapsid protein DDHD PF02862.12 CDI85289.1 - 0.25 11.1 4.8 0.9 9.2 0.1 2.2 2 0 0 2 2 2 0 DDHD domain APC_CDC26 PF10471.4 CDI85289.1 - 5.2 7.8 18.3 2.4 8.9 2.8 2.6 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit 1 3HCDH_N PF02737.13 CDI85290.1 - 7.4e-40 136.5 0.3 2.7e-39 134.6 0.2 1.7 1 1 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.17 CDI85290.1 - 7.8e-35 119.1 0.0 1.7e-34 118.1 0.0 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain PTP_N PF12453.3 CDI85290.1 - 0.0096 15.4 1.8 0.95 9.1 0.0 2.5 2 0 0 2 2 2 2 Protein tyrosine phosphatase N terminal Methyltransf_11 PF08241.7 CDI85290.1 - 0.12 12.8 0.0 0.39 11.2 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain DUF2946 PF11162.3 CDI85291.1 - 6 7.1 10.4 0.34 11.1 1.1 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF2946) Med15 PF09606.5 CDI85292.1 - 0.00014 20.2 53.7 0.00014 20.2 37.2 2.6 3 0 0 3 3 2 2 ARC105 or Med15 subunit of Mediator complex non-fungal SAPS PF04499.10 CDI85292.1 - 0.00071 18.3 4.8 0.00071 18.3 3.3 3.0 3 0 0 3 3 3 2 SIT4 phosphatase-associated protein CAF-1_p150 PF11600.3 CDI85292.1 - 0.0035 16.7 24.0 0.0035 16.7 16.6 3.2 3 0 0 3 3 2 2 Chromatin assembly factor 1 complex p150 subunit, N-terminal CDC45 PF02724.9 CDI85292.1 - 0.0051 14.9 30.2 0.11 10.5 11.8 3.1 3 0 0 3 3 3 2 CDC45-like protein Peptidase_S49_N PF08496.5 CDI85292.1 - 0.02 14.7 26.8 0.32 10.7 12.2 2.7 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Nha1_C PF08619.5 CDI85292.1 - 0.055 12.7 35.9 0.042 13.1 8.8 3.1 3 0 0 3 3 3 0 Alkali metal cation/H+ antiporter Nha1 C terminus DDHD PF02862.12 CDI85292.1 - 0.26 11.0 43.9 0.35 10.6 11.3 3.3 3 0 0 3 3 3 0 DDHD domain DUF572 PF04502.8 CDI85292.1 - 0.26 10.4 40.0 0.081 12.1 1.1 3.1 3 0 0 3 3 3 0 Family of unknown function (DUF572) SDF PF00375.13 CDI85292.1 - 0.26 9.9 4.8 0.64 8.7 0.0 2.5 2 1 0 2 2 2 0 Sodium:dicarboxylate symporter family VIT1 PF01988.14 CDI85292.1 - 0.32 10.4 8.0 1.6 8.2 1.0 2.5 2 0 0 2 2 2 0 VIT family Zip PF02535.17 CDI85292.1 - 0.6 9.0 24.7 0.13 11.2 5.2 3.1 3 0 0 3 3 3 0 ZIP Zinc transporter RR_TM4-6 PF06459.7 CDI85292.1 - 0.86 9.4 38.0 0.058 13.2 12.6 3.1 3 0 0 3 3 3 0 Ryanodine Receptor TM 4-6 CPSF100_C PF13299.1 CDI85292.1 - 0.94 9.6 39.6 2.7 8.1 11.4 3.3 3 0 0 3 3 3 0 Cleavage and polyadenylation factor 2 C-terminal Herpes_UL87 PF03043.9 CDI85292.1 - 0.97 7.7 27.5 2.7 6.2 1.0 2.8 2 1 1 3 3 3 0 Herpesvirus UL87 family TFIIA PF03153.8 CDI85292.1 - 1.2 8.9 70.6 0.22 11.4 23.2 3.1 3 0 0 3 3 3 0 Transcription factor IIA, alpha/beta subunit UPF0564 PF10595.4 CDI85292.1 - 1.5 7.6 51.4 1.1 8.1 24.9 2.3 2 1 0 2 2 2 0 Uncharacterised protein family UPF0564 Raftlin PF15250.1 CDI85292.1 - 1.5 7.2 43.0 0.01 14.4 11.0 3.1 3 0 0 3 3 3 0 Raftlin Mem_trans PF03547.13 CDI85292.1 - 2.1 6.5 27.0 0.031 12.5 1.5 3.1 3 0 0 3 3 3 0 Membrane transport protein DUF1510 PF07423.6 CDI85292.1 - 2.3 7.5 52.7 0.96 8.7 17.9 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1510) OPT PF03169.10 CDI85292.1 - 2.5 6.4 8.5 2.1 6.6 0.2 2.6 3 0 0 3 3 3 0 OPT oligopeptide transporter protein Ndc1_Nup PF09531.5 CDI85292.1 - 3.4 5.9 38.4 0.11 10.9 6.3 3.1 3 0 0 3 3 3 0 Nucleoporin protein Ndc1-Nup K_trans PF02705.11 CDI85292.1 - 3.9 5.7 10.9 0.23 9.7 3.1 2.0 2 0 0 2 2 2 0 K+ potassium transporter Shadoo PF14999.1 CDI85292.1 - 5.1 6.9 24.2 0.34 10.7 2.8 4.1 4 0 0 4 4 4 0 Shadow of prion protein, neuroprotective Utp11 PF03998.8 CDI85292.1 - 6.3 6.5 42.9 0.065 13.0 13.1 3.0 3 0 0 3 3 3 0 Utp11 protein NARP1 PF12569.3 CDI85292.1 - 6.9 5.2 33.5 5.8 5.5 1.5 2.2 2 0 0 2 2 2 0 NMDA receptor-regulated protein 1 AUX_IAA PF02309.11 CDI85292.1 - 7.5 6.2 43.0 2.6 7.7 11.8 3.2 3 0 0 3 3 3 0 AUX/IAA family FAM60A PF15396.1 CDI85292.1 - 9 5.9 43.5 3.8 7.2 2.5 3.2 3 0 0 3 3 3 0 Protein Family FAM60A FKS1_dom1 PF14288.1 CDI85294.1 - 0.68 9.8 4.3 2.5 8.0 3.0 2.0 1 0 0 1 1 1 0 1,3-beta-glucan synthase subunit FKS1, domain-1 DDHD PF02862.12 CDI85295.1 - 0.083 12.6 11.6 0.1 12.3 8.0 1.2 1 0 0 1 1 1 0 DDHD domain Rad54_N PF08658.5 CDI85295.1 - 0.19 11.4 10.8 0.33 10.6 1.0 2.0 2 0 0 2 2 2 0 Rad54 N terminal 7tm_1 PF00001.16 CDI85295.1 - 0.2 10.7 4.1 0.29 10.2 2.8 1.2 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) Alpha-amylase_N PF02903.9 CDI85295.1 - 0.35 10.8 9.4 0.44 10.5 6.5 1.1 1 0 0 1 1 1 0 Alpha amylase, N-terminal ig-like domain DUF3474 PF11960.3 CDI85295.1 - 0.43 10.5 7.3 0.55 10.2 5.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3474) Rtf2 PF04641.7 CDI85295.1 - 0.59 9.2 13.8 0.75 8.9 9.6 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger DivIC PF04977.10 CDI85295.1 - 0.62 9.5 32.0 0.81 9.2 8.5 2.1 2 0 0 2 2 2 0 Septum formation initiator OAD_gamma PF04277.8 CDI85295.1 - 0.67 10.3 2.9 14 6.1 0.1 2.1 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain DUF4175 PF13779.1 CDI85295.1 - 0.7 7.5 40.2 1 6.9 27.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) DUF177 PF02620.12 CDI85295.1 - 0.7 9.9 7.0 5.1 7.1 0.9 2.1 2 0 0 2 2 2 0 Uncharacterized ACR, COG1399 Trp_oprn_chp PF09534.5 CDI85295.1 - 0.78 9.3 3.0 0.96 9.0 2.1 1.1 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) PBP1_TM PF14812.1 CDI85295.1 - 1 9.7 9.3 2.6 8.4 0.7 2.1 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal eIF-3_zeta PF05091.7 CDI85295.1 - 1.1 7.7 16.7 1.5 7.3 11.6 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Presenilin PF01080.12 CDI85295.1 - 2.8 6.6 10.2 3 6.5 7.1 1.1 1 0 0 1 1 1 0 Presenilin Zip PF02535.17 CDI85295.1 - 2.9 6.8 7.3 3.8 6.4 5.1 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter DUF1675 PF07897.6 CDI85295.1 - 2.9 7.6 10.5 3.4 7.4 7.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) Herpes_env PF01673.13 CDI85295.1 - 3.2 6.1 10.7 3.9 5.9 7.4 1.2 1 0 0 1 1 1 0 Herpesvirus putative major envelope glycoprotein GPCR_chapero_1 PF11904.3 CDI85295.1 - 3.2 6.8 12.7 3.7 6.6 8.8 1.1 1 0 0 1 1 1 0 GPCR-chaperone Herpes_UL87 PF03043.9 CDI85295.1 - 3.2 6.0 11.1 3.3 5.9 7.7 1.0 1 0 0 1 1 1 0 Herpesvirus UL87 family ICE2 PF08426.5 CDI85295.1 - 3.4 6.1 5.2 4.1 5.9 3.6 1.1 1 0 0 1 1 1 0 ICE2 Herpes_DNAp_acc PF04929.7 CDI85295.1 - 4.6 6.1 12.4 5.3 5.8 8.6 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor TFIIA PF03153.8 CDI85295.1 - 4.8 6.9 29.4 6.5 6.5 20.4 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Conotoxin PF02950.12 CDI85295.1 - 6.4 7.6 13.0 10 7.0 1.5 2.1 2 0 0 2 2 2 0 Conotoxin AAA_11 PF13086.1 CDI85295.1 - 6.9 6.1 15.7 9.1 5.7 10.8 1.1 1 0 0 1 1 1 0 AAA domain XAP5 PF04921.9 CDI85295.1 - 9 5.7 15.2 12 5.4 10.5 1.2 1 0 0 1 1 1 0 XAP5, circadian clock regulator Imm5 PF14423.1 CDI85297.1 - 0.069 12.7 0.2 0.069 12.7 0.1 2.6 2 1 1 3 3 3 0 Immunity protein Imm5 NAD_synthase PF02540.12 CDI85298.1 - 0.00052 19.0 0.1 0.0014 17.5 0.0 1.7 2 0 0 2 2 2 1 NAD synthase MSP1_C PF07462.6 CDI85298.1 - 0.0059 15.0 7.1 0.0079 14.6 4.9 1.1 1 0 0 1 1 1 1 Merozoite surface protein 1 (MSP1) C-terminus Activator_LAG-3 PF11498.3 CDI85298.1 - 0.031 13.0 13.3 0.037 12.7 9.2 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 CDK2AP PF09806.4 CDI85298.1 - 0.04 14.1 12.1 0.055 13.7 8.4 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein CALCOCO1 PF07888.6 CDI85298.1 - 0.15 10.3 6.3 0.2 9.9 4.4 1.1 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like QueC PF06508.8 CDI85298.1 - 0.16 11.1 1.8 1.4 8.1 0.0 2.1 2 0 0 2 2 2 0 Queuosine biosynthesis protein QueC Spt20 PF12090.3 CDI85298.1 - 0.2 10.9 3.4 0.25 10.6 2.3 1.2 1 0 0 1 1 1 0 Spt20 family ATP_bind_3 PF01171.15 CDI85298.1 - 0.34 10.3 0.0 0.34 10.3 0.0 2.1 2 0 0 2 2 2 0 PP-loop family DUF3347 PF11827.3 CDI85298.1 - 0.61 10.0 13.3 0.85 9.5 9.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3347) TraV PF09676.5 CDI85298.1 - 0.74 10.5 5.6 1.5 9.4 3.9 1.5 1 0 0 1 1 1 0 Type IV conjugative transfer system lipoprotein (TraV) Med15 PF09606.5 CDI85298.1 - 1.1 7.3 19.9 1.4 7.0 13.8 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF2413 PF10310.4 CDI85298.1 - 1.1 7.9 11.8 1.5 7.5 8.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) cwf18 PF08315.7 CDI85298.1 - 1.5 9.2 9.1 2.2 8.7 6.3 1.1 1 0 0 1 1 1 0 cwf18 pre-mRNA splicing factor EAP30 PF04157.11 CDI85298.1 - 5.3 6.1 10.2 6.7 5.8 7.1 1.2 1 0 0 1 1 1 0 EAP30/Vps36 family Hid1 PF12722.2 CDI85298.1 - 6.7 4.2 5.9 8.1 3.9 4.1 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF3138 PF11336.3 CDI85298.1 - 8.1 4.4 13.6 10 4.1 9.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Peptidase_S64 PF08192.6 CDI85298.1 - 9.3 4.4 7.9 12 4.0 5.5 1.0 1 0 0 1 1 1 0 Peptidase family S64 Band_3_cyto PF07565.8 CDI85298.1 - 9.9 5.5 7.4 12 5.3 5.1 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain ERF PF04404.7 CDI85299.1 - 0.01 15.3 7.9 0.011 15.2 5.4 1.1 1 0 0 1 1 1 0 ERF superfamily DUF788 PF05620.6 CDI85299.1 - 0.1 12.4 5.6 0.088 12.6 3.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF788) CagX PF03524.10 CDI85299.1 - 0.11 11.7 3.2 0.099 11.9 2.2 1.1 1 0 0 1 1 1 0 Conjugal transfer protein Spt20 PF12090.3 CDI85299.1 - 0.19 11.0 8.6 0.18 11.1 6.0 1.1 1 0 0 1 1 1 0 Spt20 family zf-DHHC PF01529.15 CDI85299.1 - 0.52 9.6 2.7 0.48 9.7 1.9 1.1 1 0 0 1 1 1 0 DHHC palmitoyltransferase OATP PF03137.15 CDI85299.1 - 0.8 7.6 2.9 0.73 7.8 2.0 1.0 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family G0-G1_switch_2 PF15103.1 CDI85299.1 - 0.87 9.8 5.4 0.92 9.7 3.7 1.1 1 0 0 1 1 1 0 G0/G1 switch protein 2 Serinc PF03348.10 CDI85299.1 - 0.98 8.0 4.1 0.87 8.2 2.8 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) Suf PF05843.9 CDI85299.1 - 1.3 8.6 11.7 1.2 8.7 8.1 1.0 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF4407 PF14362.1 CDI85299.1 - 2.4 7.0 8.2 2.3 7.0 5.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) FimP PF09766.4 CDI85299.1 - 3.4 6.6 19.6 3.5 6.5 13.6 1.0 1 0 0 1 1 1 0 Fms-interacting protein DUF1071 PF06378.6 CDI85299.1 - 4.4 6.4 8.9 5.1 6.2 6.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1071) DUF2638 PF10937.3 CDI85301.1 - 0.0055 17.7 0.0 0.0055 17.7 0.0 2.8 2 1 1 3 3 3 1 Protein of unknown function (DUF2638) Med15 PF09606.5 CDI85301.1 - 0.038 12.2 38.0 0.042 12.0 26.4 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal AUX_IAA PF02309.11 CDI85301.1 - 0.047 13.4 6.1 0.059 13.1 4.2 1.1 1 0 0 1 1 1 0 AUX/IAA family TFIIA PF03153.8 CDI85301.1 - 0.62 9.8 20.5 0.77 9.5 14.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Neur_chan_memb PF02932.11 CDI85301.1 - 0.7 9.7 5.0 0.82 9.5 3.5 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Hid1 PF12722.2 CDI85301.1 - 0.86 7.1 6.8 0.97 7.0 4.7 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein PAT1 PF09770.4 CDI85301.1 - 0.92 7.6 36.2 1.1 7.4 25.1 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 eIF-3_zeta PF05091.7 CDI85301.1 - 1.1 7.8 8.2 1.2 7.6 5.7 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Ndc1_Nup PF09531.5 CDI85301.1 - 2.7 6.3 9.5 3.1 6.1 6.6 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Suf PF05843.9 CDI85301.1 - 3.1 7.4 15.9 4 7.0 11.0 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DDRGK PF09756.4 CDI85301.1 - 4.2 6.7 12.5 6.1 6.2 8.6 1.2 1 0 0 1 1 1 0 DDRGK domain Band_3_cyto PF07565.8 CDI85301.1 - 5.5 6.4 10.1 7.1 6.0 7.0 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Ribosomal_L11 PF00298.14 CDI85303.1 - 8e-21 73.9 0.0 1.1e-20 73.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Ribosomal_L11_N PF03946.9 CDI85303.1 - 1.3e-08 34.2 0.0 2.6e-08 33.1 0.0 1.5 2 0 0 2 2 2 1 Ribosomal protein L11, N-terminal domain DUF572 PF04502.8 CDI85304.1 - 5.9e-75 252.4 12.7 1.4e-74 251.2 8.8 1.5 1 1 0 1 1 1 1 Family of unknown function (DUF572) DUF605 PF04652.11 CDI85304.1 - 0.25 10.7 15.0 0.4 10.0 10.4 1.3 1 0 0 1 1 1 0 Vta1 like Herpes_pp85 PF04637.7 CDI85304.1 - 0.95 7.6 7.4 1.4 7.1 5.1 1.3 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) Pox_A12 PF04651.8 CDI85304.1 - 3 7.9 20.0 5.6 7.0 13.9 1.4 1 0 0 1 1 1 0 Poxvirus A12 protein DUF2407_C PF13373.1 CDI85305.1 - 2.1 8.2 5.0 0.59 10.0 0.9 1.9 2 0 0 2 2 2 0 DUF2407 C-terminal domain Rho_Binding PF08912.6 CDI85305.1 - 5.9 7.2 14.0 2.2 8.6 3.0 3.1 2 0 0 2 2 2 0 Rho Binding VIT1 PF01988.14 CDI85306.1 - 0.049 13.1 20.8 0.44 9.9 14.4 1.9 1 1 0 1 1 1 0 VIT family DUF1510 PF07423.6 CDI85306.1 - 0.23 10.7 21.4 0.32 10.3 14.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Med15 PF09606.5 CDI85306.1 - 0.61 8.2 79.9 0.67 8.0 55.4 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Neur_chan_memb PF02932.11 CDI85306.1 - 0.72 9.6 21.3 0.9 9.3 14.8 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region SAGA-Tad1 PF12767.2 CDI85306.1 - 0.84 9.2 27.2 0.95 9.0 18.9 1.0 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit GAGA_bind PF06217.7 CDI85306.1 - 0.84 9.5 28.9 0.98 9.3 20.0 1.0 1 0 0 1 1 1 0 GAGA binding protein-like family U79_P34 PF03064.11 CDI85306.1 - 0.95 8.9 21.8 1.2 8.6 15.1 1.0 1 0 0 1 1 1 0 HSV U79 / HCMV P34 PAT1 PF09770.4 CDI85306.1 - 2 6.5 63.7 2.2 6.4 44.2 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 FTCD_C PF04961.7 CDI85306.1 - 3.2 7.1 12.3 0.71 9.2 6.3 1.5 1 1 0 1 1 1 0 Formiminotransferase-cyclodeaminase Caldesmon PF02029.10 CDI85306.1 - 3.6 5.8 21.4 4.5 5.5 14.8 1.1 1 0 0 1 1 1 0 Caldesmon Ycf1 PF05758.7 CDI85306.1 - 4.2 4.9 24.3 4.5 4.8 16.9 1.0 1 0 0 1 1 1 0 Ycf1 DUF4045 PF13254.1 CDI85306.1 - 5.4 6.1 23.1 6.3 5.9 16.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Ctr PF04145.10 CDI85306.1 - 5.8 6.9 23.5 1.1e+03 -0.5 16.3 2.2 1 1 0 1 1 1 0 Ctr copper transporter family Hid1 PF12722.2 CDI85306.1 - 6.8 4.2 29.3 7.2 4.1 20.3 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein FAM60A PF15396.1 CDI85306.1 - 7.8 6.1 24.1 11 5.6 16.7 1.3 1 0 0 1 1 1 0 Protein Family FAM60A DUF3801 PF12687.2 CDI85308.1 - 0.042 13.4 16.3 0.057 12.9 11.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3801) DDRGK PF09756.4 CDI85308.1 - 1.5 8.1 22.4 0.65 9.3 11.7 2.1 2 0 0 2 2 2 0 DDRGK domain AAA_23 PF13476.1 CDI85308.1 - 2.5 8.3 18.8 3.3 7.9 13.0 1.1 1 0 0 1 1 1 0 AAA domain Hid1 PF12722.2 CDI85308.1 - 2.9 5.4 23.2 3.1 5.3 16.1 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DHquinase_II PF01220.14 CDI85308.1 - 3.6 6.9 10.0 0.54 9.5 3.8 1.9 2 0 0 2 2 2 0 Dehydroquinase class II Nop53 PF07767.6 CDI85308.1 - 3.6 6.4 28.3 5.1 5.9 19.6 1.3 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) DUF4647 PF15504.1 CDI85308.1 - 4 6.1 28.7 7.1 5.3 19.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4647) Dicty_REP PF05086.7 CDI85308.1 - 5.1 4.7 18.3 5.9 4.5 12.7 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Exonuc_VII_L PF02601.10 CDI85308.1 - 7.4 5.6 25.5 12 4.9 17.7 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit Na_trans_assoc PF06512.8 CDI85310.1 - 0.89 9.4 7.9 1.5 8.7 5.5 1.4 1 0 0 1 1 1 0 Sodium ion transport-associated Kazal_1 PF00050.16 CDI85311.1 - 1.7e-17 63.1 20.7 2.5e-11 43.3 4.3 4.7 3 0 0 3 3 3 2 Kazal-type serine protease inhibitor domain Kazal_2 PF07648.10 CDI85311.1 - 2.7e-14 52.8 13.7 3.6e-10 39.6 1.7 5.6 5 1 0 5 5 5 2 Kazal-type serine protease inhibitor domain SR-25 PF10500.4 CDI85311.1 - 0.0049 16.3 9.0 0.0049 16.3 6.2 5.0 4 1 1 5 5 5 1 Nuclear RNA-splicing-associated protein Synaptobrevin PF00957.16 CDI85313.1 - 5.1e-24 83.6 1.0 8.9e-24 82.9 0.7 1.3 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.1 CDI85313.1 - 3.2e-21 74.6 0.0 6.3e-21 73.7 0.0 1.5 1 0 0 1 1 1 1 Regulated-SNARE-like domain DUF3485 PF11984.3 CDI85315.1 - 2.3 7.2 4.8 5.5 6.0 0.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3485) ADP_ribosyl_GH PF03747.9 CDI85315.1 - 5.7 6.6 20.1 4.1 7.1 4.4 2.1 1 1 1 2 2 2 0 ADP-ribosylglycohydrolase BAF1_ABF1 PF04684.8 CDI85315.1 - 6 5.6 23.4 0.077 11.8 4.3 2.3 1 1 1 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor CDC27 PF09507.5 CDI85315.1 - 6.1 5.9 18.5 8.6 5.4 12.9 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 CRA PF06589.6 CDI85315.1 - 6.1 6.1 10.5 0.11 11.8 0.4 2.1 2 0 0 2 2 2 0 Circumsporozoite-related antigen (CRA) ASFV_J13L PF05568.6 CDI85315.1 - 6.7 6.2 9.5 7.5 6.0 2.0 2.2 2 0 0 2 2 2 0 African swine fever virus J13L protein IncA PF04156.9 CDI85316.1 - 2e-06 27.5 7.3 2.6e-06 27.1 5.1 1.0 1 0 0 1 1 1 1 IncA protein CD20 PF04103.10 CDI85316.1 - 0.00014 21.8 1.0 0.00019 21.3 0.7 1.2 1 0 0 1 1 1 1 CD20-like family VIT1 PF01988.14 CDI85316.1 - 0.00017 21.1 5.2 0.00021 20.8 3.6 1.1 1 0 0 1 1 1 1 VIT family FimP PF09766.4 CDI85316.1 - 0.00024 20.2 15.0 0.00024 20.2 10.4 1.1 1 0 0 1 1 1 1 Fms-interacting protein Bud13 PF09736.4 CDI85316.1 - 0.0083 16.3 10.0 0.0093 16.2 6.9 1.1 1 0 0 1 1 1 1 Pre-mRNA-splicing factor of RES complex DUF677 PF05055.7 CDI85316.1 - 0.0083 14.8 1.3 0.0098 14.6 0.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF677) Choline_transpo PF04515.7 CDI85316.1 - 0.0099 14.6 1.2 0.011 14.4 0.8 1.1 1 0 0 1 1 1 1 Plasma-membrane choline transporter FHIPEP PF00771.15 CDI85316.1 - 0.011 14.1 9.6 0.012 13.9 6.7 1.0 1 0 0 1 1 1 0 FHIPEP family HemX PF04375.9 CDI85316.1 - 0.011 14.3 30.5 0.014 14.0 21.1 1.0 1 0 0 1 1 1 0 HemX DUF2232 PF09991.4 CDI85316.1 - 0.015 14.2 9.6 0.017 14.1 6.6 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) DUF2217 PF10265.4 CDI85316.1 - 0.018 13.8 5.8 0.019 13.7 4.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) Serinc PF03348.10 CDI85316.1 - 0.02 13.5 13.4 0.024 13.3 9.3 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) Ctr PF04145.10 CDI85316.1 - 0.021 14.8 4.3 0.025 14.6 3.0 1.2 1 0 0 1 1 1 0 Ctr copper transporter family Peptidase_S49_N PF08496.5 CDI85316.1 - 0.021 14.6 6.6 0.025 14.3 4.6 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Med15 PF09606.5 CDI85316.1 - 0.06 11.5 43.4 0.067 11.3 30.1 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal FPN1 PF06963.7 CDI85316.1 - 0.062 11.6 6.0 0.072 11.4 4.1 1.0 1 0 0 1 1 1 0 Ferroportin1 (FPN1) FAM222A PF15258.1 CDI85316.1 - 0.063 12.4 20.4 0.079 12.1 14.2 1.1 1 0 0 1 1 1 0 Protein family of FAM222A OATP PF03137.15 CDI85316.1 - 0.076 11.0 5.4 0.079 10.9 3.7 1.2 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Suf PF05843.9 CDI85316.1 - 0.084 12.5 17.8 0.093 12.4 12.4 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Activator_LAG-3 PF11498.3 CDI85316.1 - 0.085 11.5 38.0 0.096 11.4 26.3 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 OPT PF03169.10 CDI85316.1 - 0.088 11.2 2.8 0.1 10.9 1.9 1.1 1 0 0 1 1 1 0 OPT oligopeptide transporter protein DUF4526 PF15029.1 CDI85316.1 - 0.095 12.2 7.5 0.11 12.0 5.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4526) NARP1 PF12569.3 CDI85316.1 - 0.1 11.3 12.8 0.12 11.1 8.9 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 SelP_N PF04592.9 CDI85316.1 - 0.11 11.8 9.2 0.12 11.7 6.4 1.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region CKAP2_C PF15297.1 CDI85316.1 - 0.11 11.2 10.9 0.12 11.1 7.5 1.1 1 0 0 1 1 1 0 Cytoskeleton-associated protein 2 C-terminus Trp_oprn_chp PF09534.5 CDI85316.1 - 0.12 11.9 16.4 0.14 11.7 11.4 1.1 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DcuA_DcuB PF03605.9 CDI85316.1 - 0.13 11.0 3.9 0.14 10.9 2.7 1.0 1 0 0 1 1 1 0 Anaerobic c4-dicarboxylate membrane transporter DUF4557 PF15101.1 CDI85316.1 - 0.14 12.0 21.6 0.17 11.6 15.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) PAT1 PF09770.4 CDI85316.1 - 0.14 10.3 30.5 0.15 10.2 21.1 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 PEX11 PF05648.9 CDI85316.1 - 0.15 11.2 3.2 0.18 11.0 2.2 1.1 1 0 0 1 1 1 0 Peroxisomal biogenesis factor 11 (PEX11) DUF533 PF04391.7 CDI85316.1 - 0.18 11.1 21.5 0.25 10.7 14.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF533) Rhabdo_ncap PF00945.13 CDI85316.1 - 0.19 10.2 5.8 0.21 10.1 4.0 1.1 1 0 0 1 1 1 0 Rhabdovirus nucleocapsid protein Folate_carrier PF01770.13 CDI85316.1 - 0.2 10.1 6.7 0.24 9.8 4.6 1.2 1 0 0 1 1 1 0 Reduced folate carrier RR_TM4-6 PF06459.7 CDI85316.1 - 0.2 11.5 11.3 0.22 11.3 7.8 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Bac_luciferase PF00296.15 CDI85316.1 - 0.25 10.4 10.2 0.33 10.0 7.0 1.1 1 0 0 1 1 1 0 Luciferase-like monooxygenase Raftlin PF15250.1 CDI85316.1 - 0.26 9.7 10.7 0.3 9.5 7.4 1.0 1 0 0 1 1 1 0 Raftlin DivIC PF04977.10 CDI85316.1 - 0.32 10.5 19.1 0.48 9.9 13.2 1.2 1 0 0 1 1 1 0 Septum formation initiator AUX_IAA PF02309.11 CDI85316.1 - 0.32 10.6 10.8 0.34 10.6 7.5 1.1 1 0 0 1 1 1 0 AUX/IAA family eIF-3_zeta PF05091.7 CDI85316.1 - 0.34 9.4 12.7 0.34 9.4 8.8 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF106 PF01956.11 CDI85316.1 - 0.36 10.3 8.4 0.43 10.0 5.8 1.2 1 0 0 1 1 1 0 Integral membrane protein DUF106 Ycf1 PF05758.7 CDI85316.1 - 0.39 8.3 8.0 0.39 8.3 5.5 1.0 1 0 0 1 1 1 0 Ycf1 Gag_spuma PF03276.9 CDI85316.1 - 0.39 8.9 23.3 0.44 8.8 16.2 1.1 1 0 0 1 1 1 0 Spumavirus gag protein FAM60A PF15396.1 CDI85316.1 - 0.41 10.3 7.0 0.48 10.1 4.9 1.2 1 0 0 1 1 1 0 Protein Family FAM60A Tim54 PF11711.3 CDI85316.1 - 0.42 9.1 9.4 0.49 8.9 6.5 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Spc7_N PF15402.1 CDI85316.1 - 0.44 8.4 16.9 0.49 8.3 11.7 1.0 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 AMP-binding PF00501.23 CDI85316.1 - 0.46 8.8 5.8 0.52 8.6 4.0 1.0 1 0 0 1 1 1 0 AMP-binding enzyme EPL1 PF10513.4 CDI85316.1 - 0.48 10.6 9.3 0.53 10.5 6.4 1.2 1 0 0 1 1 1 0 Enhancer of polycomb-like Neur_chan_memb PF02932.11 CDI85316.1 - 0.5 10.2 6.8 0.57 10.0 4.7 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region YABBY PF04690.8 CDI85316.1 - 0.51 10.5 6.8 0.55 10.4 4.7 1.1 1 0 0 1 1 1 0 YABBY protein DUF3449 PF11931.3 CDI85316.1 - 0.57 9.6 10.6 0.66 9.4 7.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3449) Peptidase_U57 PF05582.7 CDI85316.1 - 0.57 9.1 7.0 0.61 9.0 4.9 1.1 1 0 0 1 1 1 0 YabG peptidase U57 Sec62 PF03839.11 CDI85316.1 - 0.57 9.5 4.6 0.6 9.4 3.2 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 Tetraspannin PF00335.15 CDI85316.1 - 0.57 9.4 2.7 0.62 9.2 1.9 1.2 1 0 0 1 1 1 0 Tetraspanin family DUF4011 PF13195.1 CDI85316.1 - 0.63 10.0 6.2 0.71 9.8 4.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4011) DUF913 PF06025.7 CDI85316.1 - 0.69 8.5 9.7 0.73 8.5 6.7 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DUF1980 PF09323.5 CDI85316.1 - 0.69 9.6 9.8 0.85 9.3 6.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) SID-1_RNA_chan PF13965.1 CDI85316.1 - 0.73 7.9 7.3 0.83 7.7 5.1 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DUF3357 PF11837.3 CDI85316.1 - 0.75 9.6 6.5 2.2 8.1 4.5 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF3357) PRP3 PF08572.5 CDI85316.1 - 0.75 9.1 15.2 0.89 8.8 10.6 1.1 1 0 0 1 1 1 0 pre-mRNA processing factor 3 (PRP3) Folliculin PF11704.3 CDI85316.1 - 0.95 9.0 6.6 1.1 8.8 4.6 1.3 1 0 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport Spore_coat_CotO PF14153.1 CDI85316.1 - 0.98 8.8 18.9 1.1 8.6 13.1 1.1 1 0 0 1 1 1 0 Spore coat protein CotO Baculo_PP31 PF05311.6 CDI85316.1 - 1.2 8.3 13.8 1.4 8.1 9.6 1.2 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) SprA-related PF12118.3 CDI85316.1 - 1.2 8.3 38.6 1.7 7.8 26.7 1.2 1 0 0 1 1 1 0 SprA-related family Glt_symporter PF03616.9 CDI85316.1 - 1.3 7.4 6.7 1.5 7.2 4.6 1.2 1 0 0 1 1 1 0 Sodium/glutamate symporter AAA_23 PF13476.1 CDI85316.1 - 1.3 9.3 12.5 1.3 9.2 8.7 1.1 1 0 0 1 1 1 0 AAA domain Paf1 PF03985.8 CDI85316.1 - 1.3 7.7 11.8 1.3 7.6 8.2 1.1 1 0 0 1 1 1 0 Paf1 Glyco_transf_15 PF01793.11 CDI85316.1 - 1.4 7.8 9.2 1.5 7.7 6.4 1.2 1 0 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase DUF4259 PF14078.1 CDI85316.1 - 1.4 9.4 9.1 1.7 9.1 6.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4259) UPF0052 PF01933.13 CDI85316.1 - 1.4 8.1 8.3 1.6 8.0 5.8 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0052 DUF3381 PF11861.3 CDI85316.1 - 1.4 8.3 10.0 1.6 8.1 7.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) Hid1 PF12722.2 CDI85316.1 - 1.5 6.4 11.0 1.5 6.3 7.6 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein MRP-S31 PF15433.1 CDI85316.1 - 1.5 8.1 15.8 1.9 7.8 11.0 1.1 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 FLO_LFY PF01698.11 CDI85316.1 - 1.5 7.5 15.8 1.7 7.3 10.9 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein Hamartin PF04388.7 CDI85316.1 - 1.6 7.3 16.6 1.7 7.2 11.5 1.0 1 0 0 1 1 1 0 Hamartin protein Claudin_2 PF13903.1 CDI85316.1 - 1.7 8.3 21.0 5.4 6.6 14.6 1.7 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction TFIIA PF03153.8 CDI85316.1 - 1.7 8.4 35.8 1.9 8.3 24.8 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit R_equi_Vir PF05526.6 CDI85316.1 - 1.7 8.2 16.3 2.6 7.6 11.3 1.3 1 0 0 1 1 1 0 Rhodococcus equi virulence-associated protein LCD1 PF09798.4 CDI85316.1 - 1.8 6.4 10.4 1.9 6.4 7.2 1.3 1 0 0 1 1 1 0 DNA damage checkpoint protein UPF0560 PF10577.4 CDI85316.1 - 1.8 6.7 18.5 2 6.5 12.8 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 DUF726 PF05277.7 CDI85316.1 - 2 7.2 5.7 2.2 7.0 4.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF726) ADP_ribosyl_GH PF03747.9 CDI85316.1 - 2 8.1 10.5 2.3 7.9 7.3 1.0 1 0 0 1 1 1 0 ADP-ribosylglycohydrolase Macoilin PF09726.4 CDI85316.1 - 2.1 6.5 13.2 2.4 6.3 9.1 1.0 1 0 0 1 1 1 0 Transmembrane protein Muted PF14942.1 CDI85316.1 - 2.1 8.1 13.7 2.8 7.8 9.5 1.2 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein FNIP_N PF14636.1 CDI85316.1 - 2.2 8.7 15.2 2.7 8.4 10.5 1.2 1 0 0 1 1 1 0 Folliculin-interacting protein N-terminus FixO PF02433.10 CDI85316.1 - 2.2 7.5 9.3 2.5 7.4 6.5 1.1 1 0 0 1 1 1 0 Cytochrome C oxidase, mono-heme subunit/FixO DUF2422 PF10337.4 CDI85316.1 - 2.2 6.9 16.7 2.7 6.6 11.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2422) Peptidase_S15 PF02129.13 CDI85316.1 - 2.4 7.4 13.1 2.9 7.2 9.1 1.1 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) DUF4446 PF14584.1 CDI85316.1 - 2.4 7.9 7.2 3.1 7.6 5.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) DUF2512 PF10710.4 CDI85316.1 - 2.8 7.4 5.6 4.3 6.7 3.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2512) DUF2215 PF10225.4 CDI85316.1 - 2.8 7.3 8.3 3.3 7.0 5.8 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) DUF897 PF05982.7 CDI85316.1 - 2.8 6.6 9.2 3.5 6.3 6.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF897) SSP160 PF06933.6 CDI85316.1 - 3 5.6 22.6 3.3 5.5 15.7 1.0 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Band_3_cyto PF07565.8 CDI85316.1 - 3.2 7.1 13.2 3.6 7.0 9.1 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Alpha_GJ PF03229.8 CDI85316.1 - 3.7 7.9 22.0 4.5 7.6 15.2 1.1 1 0 0 1 1 1 0 Alphavirus glycoprotein J NYN_YacP PF05991.6 CDI85316.1 - 4.1 7.1 15.5 4.8 6.9 10.7 1.1 1 0 0 1 1 1 0 YacP-like NYN domain DUF844 PF05815.6 CDI85316.1 - 4.4 6.0 17.4 4.6 5.9 12.1 1.1 1 0 0 1 1 1 0 Baculovirus protein of unknown function (DUF844) HCO3_cotransp PF00955.16 CDI85316.1 - 4.4 5.8 7.3 4.6 5.7 5.1 1.0 1 0 0 1 1 1 0 HCO3- transporter family Herpes_glycop PF01528.11 CDI85316.1 - 4.4 5.8 7.0 5.9 5.4 4.8 1.2 1 0 0 1 1 1 0 Herpesvirus glycoprotein M Paramyxo_ncap PF00973.14 CDI85316.1 - 4.5 5.8 13.6 5.4 5.6 9.4 1.0 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Rxt3 PF08642.5 CDI85316.1 - 4.5 7.5 7.9 6.2 7.1 5.5 1.4 1 1 0 1 1 1 0 Histone deacetylation protein Rxt3 Endonuc_Holl PF10107.4 CDI85316.1 - 4.6 6.9 11.0 5.3 6.7 7.6 1.2 1 0 0 1 1 1 0 Endonuclease related to archaeal Holliday junction resolvase DDRGK PF09756.4 CDI85316.1 - 4.8 6.5 16.3 6 6.2 11.3 1.1 1 0 0 1 1 1 0 DDRGK domain DDHD PF02862.12 CDI85316.1 - 4.8 6.9 15.7 5.2 6.7 10.8 1.0 1 0 0 1 1 1 0 DDHD domain DUF3373 PF11853.3 CDI85316.1 - 5 5.5 14.3 5.5 5.3 9.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) Rtf2 PF04641.7 CDI85316.1 - 5 6.2 14.6 6.6 5.8 10.1 1.2 1 0 0 1 1 1 0 Rtf2 RING-finger F-protein PF00469.15 CDI85316.1 - 5 6.4 10.5 5.8 6.2 7.3 1.1 1 0 0 1 1 1 0 Negative factor, (F-Protein) or Nef Cas1_AcylT PF07779.7 CDI85316.1 - 5.6 5.3 6.4 6.2 5.1 4.5 1.1 1 0 0 1 1 1 0 10 TM Acyl Transferase domain found in Cas1p DHHW PF14286.1 CDI85316.1 - 5.7 6.1 14.4 6.5 5.9 10.0 1.0 1 0 0 1 1 1 0 DHHW protein PBP_sp32 PF07222.7 CDI85316.1 - 5.8 6.0 19.3 7.1 5.7 13.4 1.1 1 0 0 1 1 1 0 Proacrosin binding protein sp32 PIH1 PF08190.7 CDI85316.1 - 5.8 6.2 19.5 7 5.9 13.5 1.2 1 0 0 1 1 1 0 pre-RNA processing PIH1/Nop17 Pex26 PF07163.7 CDI85316.1 - 5.9 5.7 9.6 6.4 5.5 6.7 1.1 1 0 0 1 1 1 0 Pex26 protein DUF2894 PF11445.3 CDI85316.1 - 5.9 7.0 23.1 7.1 6.8 16.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2894) Pex16 PF08610.5 CDI85316.1 - 6.2 5.7 9.8 7.2 5.5 6.8 1.1 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) Radical_SAM_N PF08497.5 CDI85316.1 - 6.7 5.5 10.4 7.1 5.4 7.2 1.0 1 0 0 1 1 1 0 Radical SAM N-terminal DOR PF14839.1 CDI85316.1 - 7.1 6.3 23.5 9.2 5.9 16.3 1.1 1 0 0 1 1 1 0 DOR family CDC27 PF09507.5 CDI85316.1 - 7.4 5.6 20.6 8.1 5.5 14.3 1.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 DUF3260 PF11658.3 CDI85316.1 - 7.5 4.5 14.5 9.7 4.2 10.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3260) Gastrin PF00918.12 CDI85316.1 - 7.7 7.3 19.0 9.8 7.0 13.2 1.2 1 0 0 1 1 1 0 Gastrin/cholecystokinin family Hom_end_hint PF05203.11 CDI85316.1 - 7.9 6.1 10.0 9.8 5.8 6.9 1.2 1 0 0 1 1 1 0 Hom_end-associated Hint EphA2_TM PF14575.1 CDI85316.1 - 8.3 6.8 10.9 15 6.0 6.5 2.1 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Peptidase_S64 PF08192.6 CDI85316.1 - 8.7 4.5 13.6 10 4.3 9.4 1.0 1 0 0 1 1 1 0 Peptidase family S64 DUF4045 PF13254.1 CDI85316.1 - 9.4 5.4 14.0 11 5.2 9.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) SseC PF04888.7 CDI85317.1 - 2.3e-06 27.1 21.9 2.3e-06 27.1 15.2 3.9 2 1 1 4 4 4 1 Secretion system effector C (SseC) like family Shadoo PF14999.1 CDI85317.1 - 0.43 10.4 19.4 0.072 12.9 4.1 2.3 2 0 0 2 2 2 0 Shadow of prion protein, neuroprotective AAA PF00004.24 CDI85319.1 - 6.7e-17 61.9 1.5 1.7e-16 60.6 0.0 2.6 3 0 0 3 3 1 1 ATPase family associated with various cellular activities (AAA) LON PF02190.11 CDI85319.1 - 4.1e-14 52.7 8.6 5.1e-14 52.4 2.0 3.2 2 1 0 2 2 2 1 ATP-dependent protease La (LON) domain AAA_5 PF07728.9 CDI85319.1 - 1.2e-06 28.2 0.0 3.3e-06 26.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Lon_C PF05362.8 CDI85319.1 - 1.5e-06 27.6 0.2 4.3e-06 26.1 0.0 1.8 2 0 0 2 2 2 1 Lon protease (S16) C-terminal proteolytic domain AAA_PrkA PF08298.6 CDI85319.1 - 3.7e-06 25.8 0.0 6.4e-06 25.1 0.0 1.3 1 0 0 1 1 1 1 PrkA AAA domain TFIIA PF03153.8 CDI85319.1 - 3.7e-05 23.8 43.8 3.7e-05 23.8 30.3 3.4 3 0 0 3 3 3 1 Transcription factor IIA, alpha/beta subunit AAA_22 PF13401.1 CDI85319.1 - 0.00019 21.5 3.3 0.0007 19.7 0.0 3.3 2 1 0 2 2 1 1 AAA domain AAA_17 PF13207.1 CDI85319.1 - 0.00022 22.0 0.0 0.00094 19.9 0.0 2.1 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 CDI85319.1 - 0.00029 19.9 0.0 0.00093 18.3 0.0 1.8 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus Med15 PF09606.5 CDI85319.1 - 0.00034 18.9 74.6 0.00034 18.9 51.7 4.2 2 1 0 2 2 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal Utp14 PF04615.8 CDI85319.1 - 0.00037 18.8 31.5 0.00037 18.8 21.8 3.3 3 0 0 3 3 3 1 Utp14 protein IstB_IS21 PF01695.12 CDI85319.1 - 0.00063 19.2 0.0 0.0029 17.0 0.0 2.2 1 0 0 1 1 1 1 IstB-like ATP binding protein MobB PF03205.9 CDI85319.1 - 0.0043 16.7 0.0 0.012 15.3 0.0 1.8 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B SR-25 PF10500.4 CDI85319.1 - 0.0047 16.4 19.7 0.0047 16.4 13.6 7.0 5 2 2 7 7 5 2 Nuclear RNA-splicing-associated protein AAA_18 PF13238.1 CDI85319.1 - 0.063 13.5 0.0 0.063 13.5 0.0 3.9 4 1 0 4 4 3 0 AAA domain Lon_C PF05362.8 CDI85320.1 - 4.2e-23 81.7 0.1 5.6e-23 81.3 0.0 1.2 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain ChlI PF13541.1 CDI85320.1 - 0.0001 21.8 0.1 0.00016 21.1 0.0 1.3 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase Pro-rich PF15240.1 CDI85320.1 - 0.025 14.6 23.1 0.029 14.4 16.0 1.2 1 0 0 1 1 1 0 Proline-rich Cul7 PF11515.3 CDI85320.1 - 0.12 12.2 0.0 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 Mouse development and cellular proliferation protein Cullin-7 PAT1 PF09770.4 CDI85320.1 - 0.56 8.3 7.9 0.59 8.3 5.5 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Herpes_LMP1 PF05297.6 CDI85320.1 - 0.89 8.4 6.9 1.1 8.1 4.8 1.1 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) Med15 PF09606.5 CDI85322.1 - 0.00079 17.7 139.0 0.001 17.4 96.4 1.0 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal PAT1 PF09770.4 CDI85322.1 - 0.0062 14.8 118.6 0.0075 14.5 82.2 1.0 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 B12D PF06522.6 CDI85322.1 - 0.15 11.7 0.1 0.15 11.7 0.0 3.6 4 1 1 5 5 5 0 NADH-ubiquinone reductase complex 1 MLRQ subunit Utp14 PF04615.8 CDI85322.1 - 0.33 9.0 51.1 0.4 8.7 35.4 1.0 1 0 0 1 1 1 0 Utp14 protein TFIIA PF03153.8 CDI85323.1 - 0.0026 17.7 26.3 0.0052 16.7 18.2 1.4 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Chorion_2 PF03964.10 CDI85323.1 - 0.0028 18.1 5.1 0.0028 18.1 3.5 6.3 5 1 0 6 6 6 1 Chorion family 2 SR-25 PF10500.4 CDI85323.1 - 0.015 14.7 4.8 0.015 14.7 3.3 3.4 4 0 0 4 4 4 0 Nuclear RNA-splicing-associated protein DUF572 PF04502.8 CDI85323.1 - 0.083 12.0 16.1 0.18 10.9 1.9 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF572) MFS_Mycoplasma PF07672.8 CDI85323.1 - 0.22 10.6 0.1 0.34 10.0 0.0 1.2 1 0 0 1 1 1 0 Mycoplasma MFS transporter zf-RING_UBOX PF13445.1 CDI85323.1 - 1 9.1 5.6 15 5.3 0.4 2.8 2 0 0 2 2 2 0 RING-type zinc-finger DUF4557 PF15101.1 CDI85323.1 - 6.4 6.5 23.6 0.2 11.4 3.7 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4557) U79_P34 PF03064.11 CDI85324.1 - 3.9e-05 23.2 11.9 3.9e-05 23.2 8.2 2.0 1 1 1 2 2 2 1 HSV U79 / HCMV P34 Pox_Ag35 PF03286.9 CDI85324.1 - 0.011 15.3 4.3 0.011 15.3 2.9 2.2 2 0 0 2 2 2 0 Pox virus Ag35 surface protein DUF1510 PF07423.6 CDI85324.1 - 0.011 15.0 24.3 0.011 15.0 16.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) Neur_chan_memb PF02932.11 CDI85324.1 - 0.012 15.5 28.4 0.035 13.9 10.8 2.2 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region CobT PF06213.7 CDI85324.1 - 0.068 12.2 34.3 0.18 10.9 2.0 2.1 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT Nha1_C PF08619.5 CDI85324.1 - 0.31 10.2 35.9 0.018 14.3 11.3 2.1 2 0 0 2 2 2 0 Alkali metal cation/H+ antiporter Nha1 C terminus FLO_LFY PF01698.11 CDI85324.1 - 0.56 8.9 38.7 0.19 10.5 14.7 2.1 2 0 0 2 2 2 0 Floricaula / Leafy protein Macoilin PF09726.4 CDI85324.1 - 0.59 8.3 47.7 0.77 7.9 33.1 1.1 1 0 0 1 1 1 0 Transmembrane protein SelP_N PF04592.9 CDI85324.1 - 0.69 9.2 33.7 0.014 14.8 10.4 2.1 2 0 0 2 2 2 0 Selenoprotein P, N terminal region Daxx PF03344.10 CDI85324.1 - 0.93 7.8 37.8 0.52 8.7 15.4 2.1 2 0 0 2 2 2 0 Daxx Family CDC45 PF02724.9 CDI85324.1 - 1.3 7.0 33.5 2 6.3 0.9 2.1 2 0 0 2 2 2 0 CDC45-like protein Na_trans_assoc PF06512.8 CDI85324.1 - 1.5 8.7 31.7 2.2 8.2 4.4 2.1 2 0 0 2 2 2 0 Sodium ion transport-associated Hid1 PF12722.2 CDI85324.1 - 1.9 6.0 46.9 0.27 8.8 16.8 2.1 2 0 0 2 2 2 0 High-temperature-induced dauer-formation protein DUF4045 PF13254.1 CDI85324.1 - 2.1 7.5 43.0 0.13 11.5 14.6 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4045) DUF3807 PF12720.2 CDI85324.1 - 4.1 7.5 49.5 6.2 6.9 21.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3807) Raftlin PF15250.1 CDI85324.1 - 4.8 5.5 38.7 0.89 8.0 15.2 2.1 2 0 0 2 2 2 0 Raftlin Spore_coat_CotO PF14153.1 CDI85324.1 - 5.4 6.4 50.4 1.7 8.0 26.5 2.2 2 0 0 2 2 2 0 Spore coat protein CotO RAP1 PF07218.6 CDI85324.1 - 5.4 4.9 18.4 7.2 4.5 12.7 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Tim54 PF11711.3 CDI85324.1 - 6.1 5.3 32.4 2.6 6.5 4.1 2.3 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 TRAP_alpha PF03896.11 CDI85324.1 - 6.1 5.7 19.1 2.1 7.2 4.9 2.4 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit TT_ORF1 PF02956.9 CDI85324.1 - 6.2 5.1 37.5 2.1 6.7 12.3 2.1 2 0 0 2 2 2 0 TT viral orf 1 AUX_IAA PF02309.11 CDI85324.1 - 8.1 6.1 41.0 3 7.5 16.1 2.2 2 0 0 2 2 2 0 AUX/IAA family PAP1 PF08601.5 CDI85324.1 - 9.2 5.8 59.2 12 5.4 41.1 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 Utp14 PF04615.8 CDI85324.1 - 9.5 4.2 51.7 1.8 6.6 21.0 2.0 2 0 0 2 2 2 0 Utp14 protein Suf PF05843.9 CDI85325.1 - 0.047 13.4 4.5 0.051 13.2 1.4 2.3 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) Spt20 PF12090.3 CDI85325.1 - 0.061 12.6 5.8 0.16 11.2 1.0 3.0 3 0 0 3 3 3 0 Spt20 family EphA2_TM PF14575.1 CDI85325.1 - 0.14 12.5 0.8 6.2 7.2 0.2 3.4 4 0 0 4 4 4 0 Ephrin type-A receptor 2 transmembrane domain DUF912 PF06024.7 CDI85325.1 - 0.23 11.5 1.8 0.81 9.7 0.3 2.6 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF4511 PF14974.1 CDI85325.1 - 1.2 8.9 5.2 6.7 6.5 0.3 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4511) SR-25 PF10500.4 CDI85326.1 - 0.061 12.7 8.8 0.094 12.1 6.1 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein CAF-1_p150 PF11600.3 CDI85326.1 - 0.61 9.4 6.7 0.89 8.8 4.6 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Ribosomal_60s PF00428.14 CDI85327.1 - 3.8 7.9 33.5 0.039 14.3 3.7 3.6 3 1 0 3 3 3 0 60s Acidic ribosomal protein Cwf_Cwc_15 PF04889.7 CDI85327.1 - 6.3 6.4 27.4 2.2 7.9 0.7 2.2 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein DRY_EERY PF09750.4 CDI85329.1 - 0.66 10.0 14.8 0.76 9.8 10.2 1.1 1 0 0 1 1 1 0 Alternative splicing regulator DUF1510 PF07423.6 CDI85329.1 - 0.93 8.8 15.9 1 8.6 11.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) NCKAP5 PF15246.1 CDI85329.1 - 1.9 7.7 20.9 2 7.7 14.5 1.0 1 0 0 1 1 1 0 Nck-associated protein 5, Peripheral clock protein DDHD PF02862.12 CDI85329.1 - 4.1 7.1 16.6 4.5 7.0 11.5 1.0 1 0 0 1 1 1 0 DDHD domain DUF4512 PF14975.1 CDI85329.1 - 4.7 8.1 11.9 6 7.7 8.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4512) SeqA PF03925.8 CDI85329.1 - 8.1 6.0 17.5 11 5.6 12.1 1.1 1 0 0 1 1 1 0 SeqA protein TCP PF03634.8 CDI85329.1 - 8.7 6.7 22.3 11 6.4 15.5 1.1 1 0 0 1 1 1 0 TCP family transcription factor FAM91_C PF14648.1 CDI85329.1 - 9.4 4.9 11.2 11 4.7 7.7 1.0 1 0 0 1 1 1 0 FAM91 C-terminus SprA-related PF12118.3 CDI85330.1 - 0.0031 16.9 26.8 0.0031 16.9 18.6 2.0 2 0 0 2 2 2 1 SprA-related family Med15 PF09606.5 CDI85330.1 - 0.013 13.7 81.1 0.014 13.6 56.2 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal PAT1 PF09770.4 CDI85330.1 - 0.013 13.7 56.0 0.015 13.6 38.8 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 GAGA_bind PF06217.7 CDI85330.1 - 0.48 10.3 21.7 0.65 9.8 15.0 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family Hid1 PF12722.2 CDI85330.1 - 1.4 6.5 22.7 1.6 6.2 15.7 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SID-1_RNA_chan PF13965.1 CDI85330.1 - 1.4 6.9 10.7 2.1 6.4 7.4 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 SAPS PF04499.10 CDI85330.1 - 2.8 6.4 19.6 3.4 6.2 13.6 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Herpes_UL87 PF03043.9 CDI85330.1 - 3.2 6.0 12.4 3.5 5.8 8.6 1.2 1 0 0 1 1 1 0 Herpesvirus UL87 family zf-DHHC PF01529.15 CDI85330.1 - 3.4 7.0 13.9 1.6 8.1 0.2 2.3 2 0 0 2 2 2 0 DHHC palmitoyltransferase Cupin_5 PF06172.6 CDI85330.1 - 3.7 7.4 10.2 5.5 6.9 7.1 1.3 1 0 0 1 1 1 0 Cupin superfamily (DUF985) Ndc1_Nup PF09531.5 CDI85330.1 - 6.9 4.9 18.5 8.1 4.7 12.8 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup BNR_3 PF13859.1 CDI85330.1 - 10 5.1 12.3 14 4.6 8.5 1.4 1 0 0 1 1 1 0 BNR repeat-like domain PAT1 PF09770.4 CDI85331.1 - 1.6 6.8 101.2 2.3 6.3 70.1 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 CPSase_L_chain PF00289.17 CDI85332.1 - 0.016 15.2 0.1 0.028 14.5 0.1 1.4 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, N-terminal domain BLVR PF06375.6 CDI85332.1 - 0.017 14.9 5.7 0.02 14.7 4.0 1.2 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) YflT PF11181.3 CDI85332.1 - 0.085 13.0 1.5 0.13 12.4 1.0 1.2 1 0 0 1 1 1 0 Heat induced stress protein YflT ExbD PF02472.11 CDI85332.1 - 0.12 12.3 0.2 0.15 12.0 0.1 1.2 1 0 0 1 1 1 0 Biopolymer transport protein ExbD/TolR Peptidase_S49_N PF08496.5 CDI85332.1 - 0.7 9.6 6.7 1 9.1 4.7 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal ETRAMP PF09716.5 CDI85332.1 - 0.86 9.5 5.0 1.3 8.9 3.5 1.5 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) Myc_N PF01056.13 CDI85333.1 - 0.0037 16.4 6.2 0.0037 16.4 4.3 2.1 1 1 1 2 2 2 1 Myc amino-terminal region Med15 PF09606.5 CDI85333.1 - 0.58 8.2 63.5 0.73 7.9 44.0 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal SOBP PF15279.1 CDI85333.1 - 0.63 10.3 25.8 0.91 9.8 17.9 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein Ribosomal_60s PF00428.14 CDI85333.1 - 0.7 10.3 4.7 0.55 10.6 1.1 2.2 2 0 0 2 2 2 0 60s Acidic ribosomal protein DUF4048 PF13257.1 CDI85333.1 - 1.4 8.5 29.2 0.02 14.5 12.5 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4048) DUF1777 PF08648.7 CDI85334.1 - 0.24 11.0 6.3 0.31 10.7 4.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) Plasmodium_Vir PF05795.6 CDI85335.1 - 1.6 7.8 6.6 2.1 7.4 4.6 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Macoilin PF09726.4 CDI85335.1 - 2.9 6.0 16.7 3.3 5.8 11.6 1.1 1 0 0 1 1 1 0 Transmembrane protein Daxx PF03344.10 CDI85336.1 - 0.096 11.1 27.6 0.12 10.8 19.1 1.1 1 0 0 1 1 1 0 Daxx Family MIP-T3 PF10243.4 CDI85336.1 - 0.29 9.5 32.6 0.39 9.1 22.6 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Gly-zipper_OmpA PF13436.1 CDI85337.1 - 0.013 15.1 37.9 0.013 15.1 26.3 3.4 1 1 2 3 3 3 0 Glycine-zipper containing OmpA-like membrane domain DUF4366 PF14283.1 CDI85338.1 - 0.44 9.9 5.0 0.34 10.3 0.5 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4366) TFIIA PF03153.8 CDI85339.1 - 0.99 9.2 23.9 1.3 8.8 16.6 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit THRAP3_BCLAF1 PF15440.1 CDI85339.1 - 4.3 5.8 20.5 5.8 5.4 14.2 1.1 1 0 0 1 1 1 0 THRAP3/BCLAF1 family OATP PF03137.15 CDI85340.1 - 0.0043 15.1 0.9 0.0077 14.3 0.1 1.7 2 0 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family Neur_chan_memb PF02932.11 CDI85340.1 - 0.084 12.7 2.8 0.25 11.1 2.0 1.7 1 1 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region PEX11 PF05648.9 CDI85340.1 - 0.099 11.9 1.7 0.094 11.9 0.2 1.6 2 0 0 2 2 2 0 Peroxisomal biogenesis factor 11 (PEX11) POPLD PF08170.7 CDI85340.1 - 0.6 9.9 4.9 1.4 8.8 3.4 1.6 1 0 0 1 1 1 0 POPLD (NUC188) domain BatA PF07584.6 CDI85340.1 - 1.1 9.4 9.3 24 5.1 0.5 3.8 3 0 0 3 3 3 0 Aerotolerance regulator N-terminal PXA PF02194.10 CDI85340.1 - 1.4 8.4 4.8 2.3 7.7 2.4 2.0 2 0 0 2 2 2 0 PXA domain EXOSC1 PF10447.4 CDI85341.1 - 1.5e-07 31.2 0.0 2.2e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 Exosome component EXOSC1/CSL4 DUF3112 PF11309.3 CDI85343.1 - 0.0094 15.7 0.5 0.02 14.6 0.3 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3112) Ninjurin PF04923.7 CDI85343.1 - 0.0094 15.6 3.0 0.0094 15.6 2.1 2.4 2 1 0 2 2 2 1 Ninjurin DUF1510 PF07423.6 CDI85343.1 - 0.011 15.1 0.1 0.011 15.1 0.1 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF1510) TFIIA PF03153.8 CDI85343.1 - 0.068 13.0 56.1 0.088 12.6 38.9 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit UPF0104 PF03706.8 CDI85343.1 - 0.31 10.2 6.3 0.41 9.8 4.3 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0104) Hid1 PF12722.2 CDI85343.1 - 0.59 7.7 30.1 0.77 7.3 20.8 1.3 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein CAF-1_p150 PF11600.3 CDI85343.1 - 1.5 8.1 40.6 2.6 7.3 28.1 1.4 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Tetraspannin PF00335.15 CDI85343.1 - 9.6 5.4 9.2 74 2.5 6.3 2.3 1 1 0 1 1 1 0 Tetraspanin family DUF4512 PF14975.1 CDI85344.1 - 0.045 14.5 5.7 0.07 13.9 4.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4512) DDHD PF02862.12 CDI85344.1 - 0.061 13.1 7.8 0.07 12.9 5.4 1.2 1 0 0 1 1 1 0 DDHD domain Cyto_heme_lyase PF01265.12 CDI85344.1 - 0.1 12.1 10.0 0.11 12.0 6.9 1.2 1 0 0 1 1 1 0 Cytochrome c/c1 heme lyase Myf5 PF12232.3 CDI85344.1 - 0.16 12.5 0.7 0.16 12.5 0.5 2.1 2 0 0 2 2 2 0 Myogenic determination factor 5 FLO_LFY PF01698.11 CDI85344.1 - 0.26 10.0 11.2 0.31 9.8 7.8 1.2 1 0 0 1 1 1 0 Floricaula / Leafy protein DUF2201_N PF13203.1 CDI85344.1 - 0.27 10.3 16.7 0.31 10.1 11.6 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain Zip PF02535.17 CDI85344.1 - 0.46 9.4 1.9 0.46 9.4 1.3 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Peroxin-13_N PF04088.8 CDI85344.1 - 0.53 10.2 7.8 6.5 6.6 3.1 2.1 2 0 0 2 2 2 0 Peroxin 13, N-terminal region CENP-L PF13092.1 CDI85344.1 - 0.58 9.9 4.1 0.4 10.4 0.2 1.9 2 0 0 2 2 2 0 Kinetochore complex Sim4 subunit Fta1 CDC45 PF02724.9 CDI85344.1 - 0.65 7.9 16.5 0.8 7.6 11.4 1.0 1 0 0 1 1 1 0 CDC45-like protein Hid1 PF12722.2 CDI85344.1 - 1.3 6.6 13.1 1.5 6.4 9.1 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Chorein_N PF12624.2 CDI85344.1 - 1.8 8.1 10.6 0.22 11.0 0.2 2.2 2 0 0 2 2 2 0 N-terminal region of Chorein, a TM vesicle-mediated sorter DUF1675 PF07897.6 CDI85344.1 - 1.8 8.3 11.6 2.2 8.0 8.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) Anoctamin PF04547.7 CDI85344.1 - 2.2 6.8 6.7 2.6 6.6 4.7 1.1 1 0 0 1 1 1 0 Calcium-activated chloride channel DUF1510 PF07423.6 CDI85344.1 - 2.3 7.5 16.3 3.2 7.0 11.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) PH_BEACH PF14844.1 CDI85344.1 - 2.7 7.8 8.3 3.5 7.5 0.1 2.3 2 0 0 2 2 2 0 PH domain associated with Beige/BEACH G-alpha PF00503.15 CDI85344.1 - 2.9 6.4 12.1 3.7 6.1 8.4 1.1 1 0 0 1 1 1 0 G-protein alpha subunit Pan_kinase PF03309.9 CDI85344.1 - 3.2 7.2 7.2 4.6 6.6 5.0 1.3 1 0 0 1 1 1 0 Type III pantothenate kinase AUX_IAA PF02309.11 CDI85344.1 - 4.2 7.0 12.5 6.2 6.5 8.6 1.3 1 0 0 1 1 1 0 AUX/IAA family RNA_pol_Rbc25 PF08292.7 CDI85344.1 - 5 7.3 10.9 8.5 6.5 0.1 2.2 2 0 0 2 2 2 0 RNA polymerase III subunit Rpc25 ERF PF04404.7 CDI85344.1 - 5.4 6.5 32.7 1.9 8.0 4.8 2.1 2 0 0 2 2 2 0 ERF superfamily eIF-3_zeta PF05091.7 CDI85344.1 - 5.8 5.4 21.5 7.7 5.0 14.9 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Rpp20 PF12328.3 CDI85344.1 - 6.5 6.4 11.9 8.1 6.0 0.1 2.2 2 0 0 2 2 2 0 Rpp20 subunit of nuclear RNase MRP and P RED_N PF07808.8 CDI85344.1 - 6.9 5.8 25.1 0.48 9.6 0.5 2.1 2 0 0 2 2 2 0 RED-like protein N-terminal region Ycf1 PF05758.7 CDI85344.1 - 7.5 4.1 13.2 10 3.7 9.1 1.2 1 0 0 1 1 1 0 Ycf1 DUF3438 PF11920.3 CDI85344.1 - 7.6 5.2 12.8 1.2 7.8 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3438) SseC PF04888.7 CDI85345.1 - 0.00014 21.2 47.5 0.00014 21.2 32.9 16.0 11 6 4 15 15 15 1 Secretion system effector C (SseC) like family DUF4207 PF13904.1 CDI85345.1 - 0.00047 19.6 18.1 0.00047 19.6 12.6 16.1 13 3 2 16 16 16 1 Domain of unknown function (DUF4207) Med15 PF09606.5 CDI85346.1 - 0.0049 15.1 9.4 0.0043 15.3 6.5 1.1 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal Afi1 PF07792.7 CDI85346.1 - 0.012 15.6 3.9 0.018 15.0 2.7 1.2 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking FCP1_C PF09309.5 CDI85346.1 - 0.016 14.5 5.3 0.021 14.1 3.7 1.2 1 0 0 1 1 1 0 FCP1, C-terminal Spt20 PF12090.3 CDI85346.1 - 0.017 14.4 2.4 0.023 14.0 1.6 1.3 1 0 0 1 1 1 0 Spt20 family DUF4175 PF13779.1 CDI85346.1 - 0.018 12.8 13.5 0.022 12.5 9.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Auxin_inducible PF02519.9 CDI85346.1 - 0.021 14.8 1.0 1.7 8.7 0.2 2.2 2 0 0 2 2 2 0 Auxin responsive protein TMEM51 PF15345.1 CDI85346.1 - 0.03 14.0 2.1 0.032 13.9 1.5 1.2 1 0 0 1 1 1 0 Transmembrane protein 51 BTV_NS2 PF04514.7 CDI85346.1 - 0.045 12.6 2.3 0.058 12.2 1.6 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 SKIP_SNW PF02731.10 CDI85346.1 - 0.075 12.4 9.7 0.12 11.8 6.7 1.2 1 0 0 1 1 1 0 SKIP/SNW domain Ycf1 PF05758.7 CDI85346.1 - 0.078 10.6 2.2 0.064 10.9 1.5 1.1 1 0 0 1 1 1 0 Ycf1 Eapp_C PF10238.4 CDI85346.1 - 0.097 12.5 5.3 0.15 11.9 3.7 1.3 1 0 0 1 1 1 0 E2F-associated phosphoprotein eIF3_subunit PF08597.5 CDI85346.1 - 0.1 12.1 9.9 9.8 5.6 6.8 2.0 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit Suf PF05843.9 CDI85346.1 - 0.12 12.1 4.8 0.18 11.4 3.4 1.4 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) AIF_C PF14721.1 CDI85346.1 - 0.14 12.4 3.2 0.22 11.7 2.2 1.2 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term DUF912 PF06024.7 CDI85346.1 - 0.16 12.0 0.5 0.28 11.2 0.3 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) FHIPEP PF00771.15 CDI85346.1 - 0.17 10.1 2.2 0.22 9.8 1.6 1.2 1 0 0 1 1 1 0 FHIPEP family MDFI PF15316.1 CDI85346.1 - 0.18 11.8 3.7 0.26 11.2 2.6 1.3 1 0 0 1 1 1 0 MyoD family inhibitor Serinc PF03348.10 CDI85346.1 - 0.18 10.4 1.6 0.21 10.2 1.1 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) FAM176 PF14851.1 CDI85346.1 - 0.18 11.4 3.1 0.29 10.8 2.1 1.4 1 0 0 1 1 1 0 FAM176 family RR_TM4-6 PF06459.7 CDI85346.1 - 0.2 11.4 5.5 0.29 11.0 3.8 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF4557 PF15101.1 CDI85346.1 - 0.33 10.7 7.9 0.3 10.8 4.6 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4557) DUF3987 PF13148.1 CDI85346.1 - 0.34 9.4 5.1 0.47 8.9 3.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) Ctr PF04145.10 CDI85346.1 - 0.52 10.3 6.8 0.74 9.8 4.7 1.3 1 1 0 1 1 1 0 Ctr copper transporter family PHD_3 PF13922.1 CDI85346.1 - 0.53 10.5 7.8 1.1 9.5 5.4 1.6 1 0 0 1 1 1 0 PHD domain of transcriptional enhancer, Asx Sec62 PF03839.11 CDI85346.1 - 0.71 9.2 3.6 1.2 8.5 2.5 1.3 1 0 0 1 1 1 0 Translocation protein Sec62 AAA_23 PF13476.1 CDI85346.1 - 1 9.6 9.8 1.7 8.9 6.8 1.4 1 0 0 1 1 1 0 AAA domain ERF PF04404.7 CDI85346.1 - 1.3 8.5 10.9 2.5 7.6 7.5 1.5 1 0 0 1 1 1 0 ERF superfamily OATP PF03137.15 CDI85346.1 - 1.8 6.5 4.3 2.3 6.1 3.0 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Pex26 PF07163.7 CDI85346.1 - 1.9 7.3 4.8 2.8 6.7 3.3 1.2 1 0 0 1 1 1 0 Pex26 protein U1snRNP70_N PF12220.3 CDI85346.1 - 2.2 8.6 13.6 2.7 8.3 8.4 1.9 2 0 0 2 2 1 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal Conotoxin PF02950.12 CDI85346.1 - 4.1 8.2 6.4 8.8 7.2 4.4 1.5 1 0 0 1 1 1 0 Conotoxin G0-G1_switch_2 PF15103.1 CDI85346.1 - 9.2 6.5 7.5 19 5.5 5.2 1.5 1 0 0 1 1 1 0 G0/G1 switch protein 2 DUF1682 PF07946.9 CDI85346.1 - 9.6 4.9 10.2 14 4.4 7.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) YjgP_YjgQ PF03739.9 CDI85347.1 - 2.6 6.6 10.9 0.39 9.4 0.5 2.2 2 0 0 2 2 2 0 Predicted permease YjgP/YjgQ family SOBP PF15279.1 CDI85347.1 - 6.6 7.0 41.2 7.1 6.9 15.8 2.2 2 0 0 2 2 2 0 Sine oculis-binding protein DUF4512 PF14975.1 CDI85348.1 - 0.24 12.2 11.7 0.32 11.8 8.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4512) zf-C3HC PF07967.8 CDI85348.1 - 1.2 8.8 10.6 1.4 8.7 7.4 1.1 1 0 0 1 1 1 0 C3HC zinc finger-like DUF3474 PF11960.3 CDI85348.1 - 2.5 8.1 7.3 2.9 7.8 5.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3474) Baculo_PP31 PF05311.6 CDI85348.1 - 3.4 6.8 16.5 3.5 6.8 11.4 1.1 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) DUF648 PF04890.8 CDI85348.1 - 8.7 5.4 15.2 8.9 5.3 10.5 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF648) Toxin_51 PF15531.1 CDI85350.1 - 0.017 14.9 3.9 0.039 13.7 2.7 1.6 1 0 0 1 1 1 0 Putative toxin 51 N6_N4_Mtase PF01555.13 CDI85350.1 - 0.23 10.9 6.7 1.4 8.3 0.1 2.2 2 0 0 2 2 2 0 DNA methylase DUF4647 PF15504.1 CDI85350.1 - 6.8 5.4 44.5 6.2 5.5 14.0 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4647) RRP7 PF12923.2 CDI85350.1 - 9.2 6.2 28.5 0.15 12.0 5.9 3.2 3 0 0 3 3 3 0 Ribosomal RNA-processing protein 7 (RRP7) DUF3381 PF11861.3 CDI85350.1 - 9.3 5.7 17.9 1.7 8.1 2.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3381) TFIIF_alpha PF05793.7 CDI85350.1 - 9.6 4.4 39.2 20 3.3 26.3 1.7 1 1 1 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Peptidase_S21 PF00716.12 CDI85351.1 - 0.4 9.9 6.5 0.44 9.8 4.5 1.0 1 0 0 1 1 1 0 Assemblin (Peptidase family S21) Claudin_2 PF13903.1 CDI85351.1 - 0.88 9.2 6.3 1 9.0 4.4 1.1 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction zf-C4H2 PF10146.4 CDI85351.1 - 1.2 9.1 4.8 1.3 8.9 3.3 1.1 1 0 0 1 1 1 0 Zinc finger-containing protein Phage-tail_3 PF13550.1 CDI85351.1 - 4 7.1 17.5 4.7 6.9 12.2 1.1 1 0 0 1 1 1 0 Putative phage tail protein DUF2890 PF11081.3 CDI85351.1 - 4.8 7.1 6.7 5.4 7.0 4.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) Fibrinogen_BP PF08017.6 CDI85352.1 - 4.9e-07 28.3 55.6 5.7e-07 28.0 38.5 1.0 1 0 0 1 1 1 1 Fibrinogen binding protein Herpes_MCP PF03122.9 CDI85352.1 - 0.33 8.2 1.8 0.35 8.1 1.2 1.2 1 0 0 1 1 1 0 Herpes virus major capsid protein SpoIIIAH PF12685.2 CDI85353.1 - 0.00054 19.5 0.0 0.00054 19.5 0.0 9.3 4 2 2 6 6 6 2 SpoIIIAH-like protein Dehydrin PF00257.14 CDI85353.1 - 0.0021 18.4 4.6 0.0021 18.4 3.2 10.3 5 3 0 5 5 5 2 Dehydrin RAP1 PF07218.6 CDI85354.1 - 9.5 4.1 13.5 14 3.5 9.3 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Med15 PF09606.5 CDI85355.1 - 0.00011 20.6 35.9 0.00011 20.6 24.9 3.4 3 1 0 3 3 3 2 ARC105 or Med15 subunit of Mediator complex non-fungal Herpes_UL87 PF03043.9 CDI85355.1 - 0.015 13.6 9.3 0.033 12.6 6.4 1.5 1 0 0 1 1 1 0 Herpesvirus UL87 family FimP PF09766.4 CDI85355.1 - 2.3 7.1 59.9 0.28 10.2 11.6 3.5 4 0 0 4 4 4 0 Fms-interacting protein Ycf1 PF05758.7 CDI85356.1 - 1.9 6.0 3.9 1.7 6.2 2.7 1.0 1 0 0 1 1 1 0 Ycf1 Peptidase_S64 PF08192.6 CDI85356.1 - 3.3 5.9 12.4 3.9 5.6 8.6 1.0 1 0 0 1 1 1 0 Peptidase family S64 PLRV_ORF5 PF01690.12 CDI85356.1 - 4.7 6.2 18.4 5.2 6.0 12.8 1.0 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Bravo_FIGEY PF13882.1 CDI85356.1 - 4.8 8.1 10.2 8.2 7.4 7.1 1.4 1 0 0 1 1 1 0 Bravo-like intracellular region DUF2029 PF09594.5 CDI85358.1 - 0.0011 18.5 4.0 0.0011 18.5 2.8 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF2029) Ribosomal_60s PF00428.14 CDI85358.1 - 0.0018 18.6 41.8 0.014 15.7 5.4 3.1 3 0 0 3 3 3 3 60s Acidic ribosomal protein YfhO PF09586.5 CDI85360.1 - 0.025 12.6 5.9 0.043 11.8 4.1 1.2 1 0 0 1 1 1 0 Bacterial membrane protein YfhO DUF4437 PF14499.1 CDI85360.1 - 0.13 11.2 8.0 0.12 11.3 4.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4437) SAPS PF04499.10 CDI85360.1 - 0.24 10.0 16.7 0.17 10.4 1.6 2.2 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein Sporozoite_P67 PF05642.6 CDI85360.1 - 0.47 8.2 55.5 0.0032 15.4 14.4 2.4 1 1 1 2 2 2 0 Sporozoite P67 surface antigen Nop25 PF09805.4 CDI85360.1 - 1.2 9.1 28.4 1.6 8.7 7.1 2.5 2 0 0 2 2 2 0 Nucleolar protein 12 (25kDa) DUF2052 PF09747.4 CDI85360.1 - 1.6 8.6 32.9 1.1 9.1 8.7 2.3 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) Plasmodium_Vir PF05795.6 CDI85360.1 - 2.5 7.2 21.6 3.6 6.7 5.6 2.2 2 0 0 2 2 2 0 Plasmodium vivax Vir protein AAA_23 PF13476.1 CDI85360.1 - 2.5 8.3 22.9 0.07 13.4 5.8 2.1 2 0 0 2 2 2 0 AAA domain Utp14 PF04615.8 CDI85360.1 - 3.2 5.8 38.5 1.4 6.9 11.4 2.1 2 0 0 2 2 2 0 Utp14 protein Tim54 PF11711.3 CDI85362.1 - 0.00081 18.0 10.3 0.0013 17.4 7.1 1.3 1 0 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 Glt_symporter PF03616.9 CDI85362.1 - 0.0086 14.6 1.4 0.0086 14.6 1.0 3.0 2 1 1 3 3 3 1 Sodium/glutamate symporter FAM60A PF15396.1 CDI85362.1 - 0.18 11.5 21.6 0.12 12.1 7.7 2.2 2 0 0 2 2 2 0 Protein Family FAM60A Porin_4 PF13609.1 CDI85362.1 - 0.42 10.0 2.3 0.55 9.6 1.6 1.2 1 0 0 1 1 1 0 Gram-negative porin Rtf2 PF04641.7 CDI85362.1 - 1.7 7.8 27.5 1.2 8.2 10.3 2.1 2 0 0 2 2 2 0 Rtf2 RING-finger DUF3357 PF11837.3 CDI85362.1 - 2.6 7.9 13.4 2.2 8.1 3.5 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF3357) Conotoxin PF02950.12 CDI85362.1 - 2.8 8.7 31.2 1.4 9.7 2.0 3.4 3 0 0 3 3 3 0 Conotoxin BRF1 PF07741.8 CDI85362.1 - 3.5 7.9 35.4 0.71 10.1 5.2 3.1 3 0 0 3 3 3 0 Brf1-like TBP-binding domain AUX_IAA PF02309.11 CDI85362.1 - 7.1 6.3 25.2 6.6 6.4 9.2 2.2 2 0 0 2 2 2 0 AUX/IAA family PBP1_TM PF14812.1 CDI85362.1 - 8 6.8 18.0 4.5 7.6 2.4 3.1 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF1632 PF07857.7 CDI85363.1 - 0.12 11.6 4.1 0.08 12.1 1.5 1.6 2 0 0 2 2 2 0 CEO family (DUF1632) EphA2_TM PF14575.1 CDI85363.1 - 0.18 12.2 0.3 0.18 12.2 0.2 2.0 2 1 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Claudin_2 PF13903.1 CDI85363.1 - 0.26 10.9 14.5 0.053 13.2 7.3 1.7 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction CcmD PF04995.9 CDI85363.1 - 0.27 10.9 2.6 0.54 10.0 1.8 1.4 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) FimP PF09766.4 CDI85363.1 - 0.56 9.2 7.6 1.8 7.5 0.2 2.0 2 0 0 2 2 2 0 Fms-interacting protein Herpes_UL32 PF06070.6 CDI85363.1 - 0.9 7.9 18.8 1.1 7.6 13.0 1.0 1 0 0 1 1 1 0 Herpesvirus large structural phosphoprotein UL32 TFIIA PF03153.8 CDI85363.1 - 1.6 8.5 30.3 2.1 8.1 21.0 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CD20 PF04103.10 CDI85363.1 - 3 7.7 6.7 13 5.6 0.3 2.2 2 0 0 2 2 2 0 CD20-like family DUF566 PF04484.7 CDI85363.1 - 4.2 6.7 23.6 6.6 6.1 16.4 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF566) DUF605 PF04652.11 CDI85363.1 - 5.6 6.2 30.2 6.8 5.9 20.9 1.1 1 0 0 1 1 1 0 Vta1 like DUF3994 PF13159.1 CDI85364.1 - 0.0068 16.6 0.0 6.5 7.0 0.0 2.8 2 0 0 2 2 2 2 Domain of unknown function (DUF3994) HTH_Tnp_Mu_2 PF09039.6 CDI85364.1 - 0.03 14.0 0.2 8.3 6.1 0.0 3.1 3 0 0 3 3 3 0 Mu DNA binding, I gamma subdomain Activator_LAG-3 PF11498.3 CDI85365.1 - 0.00017 20.4 82.6 0.00017 20.4 57.3 4.1 1 1 2 3 3 3 1 Transcriptional activator LAG-3 SR-25 PF10500.4 CDI85365.1 - 0.0081 15.6 10.4 0.0081 15.6 7.2 7.7 3 2 3 6 6 6 1 Nuclear RNA-splicing-associated protein Rft-1 PF04506.8 CDI85366.1 - 5.1e-09 35.0 0.3 6.8e-09 34.6 0.2 1.1 1 0 0 1 1 1 1 Rft protein DAP10 PF07213.6 CDI85366.1 - 6.5 6.5 10.5 1.2 8.9 3.5 2.7 2 1 1 3 3 3 0 DAP10 membrane protein Sad1_UNC PF07738.8 CDI85367.1 - 1.3e-15 57.3 0.0 2.6e-15 56.3 0.0 1.5 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal Methyltransf_18 PF12847.2 CDI85368.1 - 0.099 13.2 0.0 0.27 11.8 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain PIN_3 PF13470.1 CDI85371.1 - 9.8 6.8 7.2 1.2 9.8 0.2 2.7 2 2 0 2 2 2 0 PIN domain CorA PF01544.13 CDI85372.1 - 0.15 11.0 2.1 0.31 10.0 1.4 1.5 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Fib_alpha PF08702.5 CDI85372.1 - 0.19 11.8 1.0 1.8 8.6 0.2 2.4 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF1664 PF07889.7 CDI85372.1 - 0.2 11.4 1.2 1.1 9.1 1.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Ubiq_cyt_C_chap PF03981.7 CDI85372.1 - 0.22 11.3 2.4 0.85 9.4 0.5 2.4 2 1 0 2 2 2 0 Ubiquinol-cytochrome C chaperone DUF4404 PF14357.1 CDI85372.1 - 0.23 11.9 7.4 0.84 10.0 2.4 3.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4404) zf-HC2 PF13490.1 CDI85372.1 - 1.4 8.9 4.6 2.4 8.1 1.9 2.4 2 0 0 2 2 2 0 Putative zinc-finger AAA_13 PF13166.1 CDI85372.1 - 1.9 6.8 3.6 1.4 7.2 0.8 1.8 2 0 0 2 2 2 0 AAA domain DUF883 PF05957.8 CDI85372.1 - 2.8 8.4 12.0 0.39 11.1 4.0 2.7 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF883) Baculo_PEP_C PF04513.7 CDI85372.1 - 4.8 7.0 5.9 4.6 7.0 1.1 3.0 3 1 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF848 PF05852.6 CDI85372.1 - 8.8 6.1 9.0 5.9 6.7 4.0 2.4 2 1 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) ThiF PF00899.16 CDI85373.1 - 7.7e-35 119.6 0.1 2.6e-22 79.1 0.0 4.6 4 0 0 4 4 4 3 ThiF family UBACT PF02134.16 CDI85373.1 - 2.3e-14 52.6 0.0 1.5e-10 40.4 0.0 2.7 2 0 0 2 2 2 2 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 CDI85373.1 - 4.2e-06 26.0 0.1 1.2e-05 24.6 0.0 1.8 2 0 0 2 2 2 1 Ubiquitin-activating enzyme active site Shikimate_DH PF01488.15 CDI85373.1 - 1.4e-05 25.2 0.1 0.018 15.1 0.0 2.8 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase UBA_e1_C PF09358.5 CDI85373.1 - 9.4e-05 22.5 0.0 0.00039 20.5 0.0 2.0 1 1 0 1 1 1 1 Ubiquitin-activating enzyme e1 C-terminal domain 2-Hacid_dh_C PF02826.14 CDI85373.1 - 0.00034 19.7 0.0 0.15 11.1 0.0 3.2 3 0 0 3 3 3 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox PF00070.22 CDI85373.1 - 0.09 13.1 3.0 4.5 7.7 0.2 3.1 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase RIC1 PF07064.8 CDI85374.1 - 5e-06 26.1 0.0 1.1e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 RIC1 Glyco_transf_15 PF01793.11 CDI85376.1 - 3.2 6.5 11.3 0.12 11.3 2.6 2.2 2 0 0 2 2 2 0 Glycolipid 2-alpha-mannosyltransferase PAT1 PF09770.4 CDI85377.1 - 1.8 6.6 45.2 2.2 6.3 31.3 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Peptidase_S64 PF08192.6 CDI85379.1 - 5.9 5.0 5.5 6 5.0 3.8 1.1 1 0 0 1 1 1 0 Peptidase family S64 BUD22 PF09073.5 CDI85380.1 - 0.31 10.0 14.2 0.33 9.9 9.9 1.1 1 0 0 1 1 1 0 BUD22 DUF4614 PF15391.1 CDI85380.1 - 1.7 8.4 24.0 2.1 8.0 16.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) THRAP3_BCLAF1 PF15440.1 CDI85380.1 - 1.9 7.0 16.7 2 6.9 11.6 1.0 1 0 0 1 1 1 0 THRAP3/BCLAF1 family Hid1 PF12722.2 CDI85380.1 - 7.1 4.1 17.3 7.8 4.0 12.0 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF2029 PF09594.5 CDI85382.1 - 0.00012 21.6 15.1 0.26 10.7 0.0 3.1 3 0 0 3 3 3 3 Protein of unknown function (DUF2029) Herpes_gE PF02480.11 CDI85382.1 - 0.31 9.2 19.8 0.25 9.5 6.5 2.3 1 1 1 2 2 2 0 Alphaherpesvirus glycoprotein E Utp14 PF04615.8 CDI85382.1 - 0.62 8.1 49.0 0.79 7.8 34.0 1.1 1 0 0 1 1 1 0 Utp14 protein MRP-S31 PF15433.1 CDI85382.1 - 3.5 6.9 49.8 0.085 12.2 29.9 1.7 2 0 0 2 2 2 0 Mitochondrial 28S ribosomal protein S31 DUF4448 PF14610.1 CDI85382.1 - 7 6.0 13.5 10 5.5 0.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF4448) CPW_WPC PF09717.5 CDI85383.1 - 3.7e-18 65.8 7.3 9.2e-15 55.0 1.3 2.5 2 0 0 2 2 2 2 Plasmodium falciparum domain of unknown function (CPW_WPC) Med15 PF09606.5 CDI85383.1 - 0.008 14.4 13.4 0.0082 14.4 9.3 1.0 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal DUF3371 PF11851.3 CDI85383.1 - 0.008 16.8 4.6 0.0089 16.7 3.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3371) FCP1_C PF09309.5 CDI85383.1 - 0.028 13.7 2.2 0.032 13.5 1.5 1.2 1 0 0 1 1 1 0 FCP1, C-terminal 1-cysPrx_C PF10417.4 CDI85383.1 - 0.068 12.8 0.1 15 5.3 0.0 2.5 2 0 0 2 2 2 0 C-terminal domain of 1-Cys peroxiredoxin DUF1840 PF08895.6 CDI85383.1 - 0.29 11.1 4.1 0.39 10.7 2.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1840) UPF0542 PF15086.1 CDI85383.1 - 0.94 9.2 2.6 2.3 7.9 1.8 1.7 1 1 0 1 1 1 0 Uncharacterised protein family UPF0542 Suf PF05843.9 CDI85383.1 - 2.4 7.8 7.3 2.8 7.5 5.0 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) RED_N PF07808.8 CDI85383.1 - 3.1 6.9 10.7 4.2 6.5 7.4 1.1 1 0 0 1 1 1 0 RED-like protein N-terminal region DUF3103 PF11301.3 CDI85383.1 - 3.4 6.2 8.1 16 4.0 5.6 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3103) PKI PF02827.11 CDI85383.1 - 3.5 7.8 5.8 5.8 7.1 4.0 1.4 1 0 0 1 1 1 0 cAMP-dependent protein kinase inhibitor SLBP_RNA_bind PF15247.1 CDI85384.1 - 3.6e-17 61.8 1.9 3.6e-17 61.8 1.3 4.8 5 1 1 6 6 6 1 Histone RNA hairpin-binding protein RNA-binding domain Shadoo PF14999.1 CDI85385.1 - 0.0016 18.2 11.0 0.085 12.7 1.8 2.1 2 0 0 2 2 2 2 Shadow of prion protein, neuroprotective Ribosomal_60s PF00428.14 CDI85385.1 - 0.0059 16.9 18.4 0.25 11.7 5.3 2.3 2 0 0 2 2 2 2 60s Acidic ribosomal protein RskA PF10099.4 CDI85388.1 - 0.0023 17.7 3.0 0.0028 17.4 2.1 1.2 1 0 0 1 1 1 1 Anti-sigma-K factor rskA DUF21 PF01595.15 CDI85388.1 - 0.044 13.0 0.3 0.051 12.8 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function DUF21 Shisa PF13908.1 CDI85388.1 - 0.045 13.9 5.3 0.05 13.7 3.7 1.1 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Nucleoside_tran PF01733.13 CDI85388.1 - 0.077 12.1 4.1 0.087 11.9 2.8 1.0 1 0 0 1 1 1 0 Nucleoside transporter MLANA PF14991.1 CDI85388.1 - 0.2 11.6 0.5 0.26 11.2 0.4 1.2 1 0 0 1 1 1 0 Protein melan-A DUF4557 PF15101.1 CDI85388.1 - 0.31 10.8 6.5 0.3 10.8 4.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) TMEM51 PF15345.1 CDI85388.1 - 0.46 10.1 5.1 0.55 9.8 3.5 1.1 1 0 0 1 1 1 0 Transmembrane protein 51 TALPID3 PF15324.1 CDI85388.1 - 0.73 7.1 9.0 0.78 7.0 6.2 1.0 1 0 0 1 1 1 0 Hedgehog signalling target Endonuc_Holl PF10107.4 CDI85388.1 - 7.9 6.1 10.7 9.4 5.9 7.4 1.1 1 0 0 1 1 1 0 Endonuclease related to archaeal Holliday junction resolvase DUF4446 PF14584.1 CDI85388.1 - 8.6 6.1 13.3 84 2.9 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF4446) SET PF00856.23 CDI85389.1 - 6.8e-06 26.4 1.0 0.041 14.1 0.0 3.5 3 1 0 4 4 4 2 SET domain Tfb2 PF03849.9 CDI85391.1 - 4.8e-10 38.6 5.2 0.00054 18.7 1.5 3.1 2 1 1 3 3 3 3 Transcription factor Tfb2 DUF3807 PF12720.2 CDI85391.1 - 0.022 14.9 2.2 0.022 14.9 1.6 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3807) Med15 PF09606.5 CDI85391.1 - 0.038 12.2 26.2 0.44 8.6 0.2 2.1 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal CPSF73-100_C PF11718.3 CDI85391.1 - 0.39 10.0 7.4 0.043 13.1 1.8 1.8 2 0 0 2 2 2 0 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Secretin_N_2 PF07655.8 CDI85391.1 - 1 9.7 36.5 0.26 11.7 5.0 3.4 3 0 0 3 3 3 0 Secretin N-terminal domain Pex14_N PF04695.8 CDI85391.1 - 1.5 8.8 29.1 0.85 9.6 6.5 3.4 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region dsDNA_bind PF01984.15 CDI85391.1 - 7.6 6.5 22.2 0.51 10.3 5.9 2.7 3 0 0 3 3 3 0 Double-stranded DNA-binding domain Cullin PF00888.17 CDI85392.1 - 7.1e-17 61.1 0.0 1.6e-16 60.0 0.0 1.4 1 1 0 1 1 1 1 Cullin family DUF3446 PF11928.3 CDI85392.1 - 0.0023 18.0 2.4 0.005 17.0 1.7 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3446) BRCA-2_OB3 PF09104.5 CDI85392.1 - 0.13 12.0 0.1 0.22 11.2 0.1 1.4 1 0 0 1 1 1 0 BRCA2, oligonucleotide/oligosaccharide-binding, domain 3 DUF2611 PF11022.3 CDI85392.1 - 1.4 9.0 3.7 1.7 8.7 0.2 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2611) DUF4175 PF13779.1 CDI85392.1 - 4 5.0 14.3 5.3 4.6 9.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Activator_LAG-3 PF11498.3 CDI85392.1 - 4.2 6.0 17.6 8.2 5.0 12.2 1.4 1 0 0 1 1 1 0 Transcriptional activator LAG-3 HRXXH PF13933.1 CDI85393.1 - 0.19 11.1 7.5 0.21 10.9 5.2 1.1 1 0 0 1 1 1 0 Putative peptidase family FimP PF09766.4 CDI85393.1 - 4.8 6.1 28.5 4.7 6.1 19.7 1.1 1 0 0 1 1 1 0 Fms-interacting protein Dala_Dala_lig_N PF01820.16 CDI85393.1 - 5.9 7.2 8.3 6.3 7.1 5.8 1.2 1 0 0 1 1 1 0 D-ala D-ala ligase N-terminus FCP1_C PF09309.5 CDI85393.1 - 8.4 5.6 20.9 9.4 5.4 14.5 1.1 1 0 0 1 1 1 0 FCP1, C-terminal DUF2637 PF10935.3 CDI85395.1 - 0.015 15.2 0.0 0.054 13.4 0.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2637) DUF4519 PF15012.1 CDI85395.1 - 0.07 13.0 0.3 0.07 13.0 0.2 4.7 4 1 0 4 4 4 0 Domain of unknown function (DUF4519) DUF4401 PF14351.1 CDI85395.1 - 1.5 7.7 6.4 0.28 10.1 0.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4401) KIAA1328 PF15369.1 CDI85398.1 - 0.0024 17.7 30.0 0.0024 17.7 20.8 2.2 2 0 0 2 2 2 1 Uncharacterised protein KIAA1328 YscO PF07321.7 CDI85398.1 - 0.0057 16.4 16.1 0.0089 15.8 11.1 1.3 1 0 0 1 1 1 1 Type III secretion protein YscO Pkinase PF00069.20 CDI85399.1 - 2.5e-44 151.3 1.3 8.1e-32 110.3 0.0 2.9 2 1 1 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.12 CDI85399.1 - 5.8e-16 58.3 0.0 1.8e-12 46.8 0.0 3.3 3 1 1 4 4 4 2 Protein tyrosine kinase AMP-binding PF00501.23 CDI85400.1 - 8.2e-36 123.2 0.0 1.3e-35 122.6 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 CDI85400.1 - 0.0045 17.9 0.1 0.008 17.1 0.1 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain NYN_YacP PF05991.6 CDI85400.1 - 0.015 15.0 0.1 0.023 14.4 0.0 1.3 1 0 0 1 1 1 0 YacP-like NYN domain Creatinase_N PF01321.13 CDI85400.1 - 0.042 14.3 0.1 0.065 13.7 0.1 1.2 1 0 0 1 1 1 0 Creatinase/Prolidase N-terminal domain Shadoo PF14999.1 CDI85401.1 - 0.00031 20.5 29.3 0.21 11.4 2.3 4.4 4 0 0 4 4 4 4 Shadow of prion protein, neuroprotective Ribosomal_60s PF00428.14 CDI85401.1 - 3.8 7.9 47.2 0.75 10.2 2.3 4.5 4 0 0 4 4 4 0 60s Acidic ribosomal protein PRP1_N PF06424.7 CDI85402.1 - 0.0037 17.5 5.0 0.096 13.0 0.7 2.3 2 0 0 2 2 2 1 PRP1 splicing factor, N-terminal Ycf1 PF05758.7 CDI85402.1 - 0.0062 14.3 4.4 0.0071 14.1 3.1 1.1 1 0 0 1 1 1 1 Ycf1 PAT1 PF09770.4 CDI85402.1 - 0.018 13.3 39.4 0.021 13.0 27.3 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 K_channel_TID PF07941.6 CDI85402.1 - 0.02 15.0 9.3 0.02 15.0 6.5 4.4 3 1 1 4 4 3 0 Potassium channel Kv1.4 tandem inactivation domain CRT10 PF08728.5 CDI85402.1 - 0.075 11.0 3.2 0.08 10.9 2.2 1.1 1 0 0 1 1 1 0 CRT10 zf-DHHC PF01529.15 CDI85402.1 - 0.2 11.0 4.9 1.6 8.0 0.3 2.1 2 0 0 2 2 2 0 DHHC palmitoyltransferase U1snRNP70_N PF12220.3 CDI85402.1 - 0.2 12.0 16.3 0.8 10.0 0.4 2.2 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal FimP PF09766.4 CDI85402.1 - 0.37 9.8 28.5 1.2 8.1 5.5 2.1 2 0 0 2 2 2 0 Fms-interacting protein TFIIA PF03153.8 CDI85402.1 - 0.44 10.3 32.4 0.63 9.8 22.4 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF2971 PF11185.3 CDI85402.1 - 0.56 10.9 4.3 0.86 10.3 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2971) DUF912 PF06024.7 CDI85402.1 - 0.62 10.1 11.6 3.3 7.8 1.6 2.3 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Herpes_UL87 PF03043.9 CDI85402.1 - 0.66 8.3 7.0 0.78 8.0 4.9 1.1 1 0 0 1 1 1 0 Herpesvirus UL87 family DUF3408 PF11888.3 CDI85402.1 - 0.91 9.4 12.5 3.3 7.6 2.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3408) Peroxin-13_N PF04088.8 CDI85402.1 - 0.92 9.4 6.4 8.1 6.3 0.3 2.1 2 0 0 2 2 2 0 Peroxin 13, N-terminal region Hid1 PF12722.2 CDI85402.1 - 1.1 6.8 10.7 1.3 6.6 7.4 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein LIM_bind PF01803.11 CDI85402.1 - 1.3 8.1 23.0 0.72 8.9 6.2 2.1 2 0 0 2 2 2 0 LIM-domain binding protein YjgP_YjgQ PF03739.9 CDI85402.1 - 1.7 7.2 4.6 2.2 6.9 3.2 1.1 1 0 0 1 1 1 0 Predicted permease YjgP/YjgQ family DUF2722 PF10846.3 CDI85402.1 - 2.2 7.1 25.8 2.3 7.1 6.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) PH_4 PF15404.1 CDI85402.1 - 2.9 7.3 12.7 6.1 6.3 1.0 2.3 2 0 0 2 2 2 0 Pleckstrin homology domain DUF966 PF06136.8 CDI85402.1 - 3.1 7.1 16.4 4.9 6.4 11.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF966) CD20 PF04103.10 CDI85402.1 - 3.5 7.5 9.5 1.5 8.7 0.1 2.3 2 0 0 2 2 2 0 CD20-like family VirC2 PF07181.6 CDI85402.1 - 3.5 6.9 16.0 0.42 9.9 7.5 1.9 1 1 1 2 2 2 0 VirC2 protein DUF2072 PF09845.4 CDI85402.1 - 3.5 7.5 9.5 8.5 6.3 2.2 2.2 2 0 0 2 2 2 0 Zn-ribbon containing protein (DUF2072) Herpes_UL4 PF03277.8 CDI85402.1 - 3.6 6.7 18.0 3.2 6.9 1.4 2.3 2 0 0 2 2 2 0 Herpesvirus UL4 family Gly_rich PF12810.2 CDI85402.1 - 4.8 6.7 8.4 0.82 9.2 2.1 1.9 2 0 0 2 2 2 0 Glycine rich protein PHD_3 PF13922.1 CDI85402.1 - 6 7.1 26.7 1.2 9.4 5.5 3.3 3 0 0 3 3 3 0 PHD domain of transcriptional enhancer, Asx Rxt3 PF08642.5 CDI85402.1 - 6.5 7.0 10.8 12 6.1 2.7 2.3 2 0 0 2 2 2 0 Histone deacetylation protein Rxt3 T2SM PF04612.7 CDI85403.1 - 5.2 6.8 10.5 5.9 6.6 7.3 1.0 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein M Ndc1_Nup PF09531.5 CDI85404.1 - 0.21 9.9 10.8 0.21 9.9 7.5 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF566 PF04484.7 CDI85404.1 - 0.53 9.7 19.5 0.71 9.3 13.5 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF566) Methyltransf_26 PF13659.1 CDI85404.1 - 0.91 9.5 3.9 1.3 9.0 2.7 1.2 1 0 0 1 1 1 0 Methyltransferase domain Utp14 PF04615.8 CDI85404.1 - 2.7 6.0 7.4 3.1 5.8 5.1 1.0 1 0 0 1 1 1 0 Utp14 protein SOBP PF15279.1 CDI85404.1 - 3.7 7.8 12.3 4.9 7.4 8.5 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein 60KD_IMP PF02096.15 CDI85405.1 - 0.0013 18.4 0.9 0.0013 18.4 0.6 3.5 2 1 1 3 3 3 1 60Kd inner membrane protein Mito_carr PF00153.22 CDI85405.1 - 0.0024 17.5 0.4 0.0024 17.5 0.3 4.9 3 1 2 5 5 5 1 Mitochondrial carrier protein T2SF PF00482.18 CDI85405.1 - 5.5 6.9 0.0 5.5 6.9 0.0 4.0 6 0 0 6 6 6 0 Type II secretion system (T2SS), protein F Med15 PF09606.5 CDI85406.1 - 6.9 4.7 170.7 0.17 10.0 72.4 2.6 2 1 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal MORN PF02493.15 CDI85407.1 - 4.4e-30 101.6 34.3 2.8e-06 26.7 0.5 6.4 6 0 0 6 6 6 6 MORN repeat DUF755 PF05501.6 CDI85408.1 - 0.0013 18.8 9.8 0.0013 18.8 6.8 4.8 4 1 0 4 4 4 1 Domain of unknown function (DUF755) DUF1183 PF06682.7 CDI85408.1 - 0.006 16.2 1.3 0.006 16.2 0.9 3.2 3 0 0 3 3 3 1 Protein of unknown function (DUF1183) BRCA-2_OB1 PF09103.5 CDI85408.1 - 0.012 15.2 0.0 0.024 14.3 0.0 1.5 1 0 0 1 1 1 0 BRCA2, oligonucleotide/oligosaccharide-binding, domain 1 Spt20 PF12090.3 CDI85408.1 - 0.17 11.2 9.8 2.2 7.6 1.2 3.3 3 0 0 3 3 3 0 Spt20 family Med15 PF09606.5 CDI85409.1 - 0.00057 18.2 27.8 0.00057 18.2 19.3 1.9 2 0 0 2 2 2 1 ARC105 or Med15 subunit of Mediator complex non-fungal Corona_nucleoca PF00937.13 CDI85409.1 - 0.0018 17.3 18.9 0.0029 16.6 13.1 1.3 1 0 0 1 1 1 1 Coronavirus nucleocapsid protein CAF-1_p150 PF11600.3 CDI85409.1 - 0.005 16.2 32.0 0.005 16.2 22.2 2.3 2 1 1 3 3 3 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal CCDC84 PF14968.1 CDI85409.1 - 0.0092 15.5 17.2 0.012 15.1 12.0 1.1 1 0 0 1 1 1 1 Coiled coil protein 84 DUF1625 PF07787.7 CDI85409.1 - 0.023 13.9 4.9 0.029 13.6 3.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1625) Activator_LAG-3 PF11498.3 CDI85409.1 - 0.029 13.1 30.8 0.046 12.4 21.4 1.3 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Suf PF05843.9 CDI85409.1 - 0.037 13.7 13.0 0.045 13.4 9.0 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) SPX PF03105.14 CDI85409.1 - 0.07 12.8 14.1 0.09 12.5 9.8 1.3 1 0 0 1 1 1 0 SPX domain FemAB PF02388.11 CDI85409.1 - 0.68 8.5 13.4 0.97 8.0 9.3 1.3 1 0 0 1 1 1 0 FemAB family GAGA_bind PF06217.7 CDI85409.1 - 0.74 9.7 12.9 0.83 9.5 8.9 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family PLRV_ORF5 PF01690.12 CDI85409.1 - 0.82 8.7 19.0 1 8.4 13.2 1.3 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein FLO_LFY PF01698.11 CDI85409.1 - 0.82 8.4 12.4 0.96 8.2 8.6 1.3 1 0 0 1 1 1 0 Floricaula / Leafy protein CDC37_N PF03234.9 CDI85409.1 - 1.5 9.1 18.3 2.1 8.6 12.7 1.2 1 0 0 1 1 1 0 Cdc37 N terminal kinase binding DUF342 PF03961.8 CDI85409.1 - 1.6 7.0 10.8 1.9 6.8 7.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) V_ATPase_I PF01496.14 CDI85409.1 - 1.6 6.5 17.2 2 6.1 11.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Peptidase_U57 PF05582.7 CDI85409.1 - 2.2 7.2 10.3 3 6.7 7.1 1.2 1 0 0 1 1 1 0 YabG peptidase U57 DUF1266 PF06889.6 CDI85409.1 - 4.1 7.1 11.6 8.5 6.1 8.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1266) Het-C PF07217.6 CDI85409.1 - 5.9 4.9 13.9 7.8 4.5 9.6 1.1 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C AAA_23 PF13476.1 CDI85409.1 - 8.5 6.6 20.3 12 6.1 14.1 1.2 1 0 0 1 1 1 0 AAA domain DUF106 PF01956.11 CDI85409.1 - 9 5.7 9.8 14 5.1 6.8 1.4 1 0 0 1 1 1 0 Integral membrane protein DUF106 Mnd1 PF03962.10 CDI85409.1 - 9.6 5.8 22.7 16 5.1 15.8 1.2 1 0 0 1 1 1 0 Mnd1 family B-block_TFIIIC PF04182.7 CDI85410.1 - 8.1e-09 35.2 0.0 1.1e-08 34.8 0.0 1.3 1 0 0 1 1 1 1 B-block binding subunit of TFIIIC HTH_5 PF01022.15 CDI85410.1 - 0.071 12.7 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family MarR PF01047.17 CDI85410.1 - 0.12 12.0 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 MarR family Med15 PF09606.5 CDI85411.1 - 0.00016 20.0 103.3 0.00016 20.0 71.6 4.2 2 1 1 4 4 4 1 ARC105 or Med15 subunit of Mediator complex non-fungal DUF3742 PF12553.3 CDI85411.1 - 0.047 14.1 0.6 0.047 14.1 0.4 3.4 4 0 0 4 4 4 0 Protein of unknown function (DUF3742) OAD_gamma PF04277.8 CDI85413.1 - 0.005 17.1 0.1 0.005 17.1 0.0 2.2 2 0 0 2 2 1 1 Oxaloacetate decarboxylase, gamma chain Protocadherin PF08374.6 CDI85413.1 - 0.018 14.7 0.8 0.019 14.6 0.6 1.2 1 0 0 1 1 1 0 Protocadherin Cation_efflux PF01545.16 CDI85413.1 - 0.021 13.8 0.0 0.026 13.5 0.0 1.1 1 0 0 1 1 1 0 Cation efflux family Tom37_C PF11801.3 CDI85413.1 - 0.023 14.5 8.2 0.038 13.8 5.7 1.3 1 0 0 1 1 1 0 Tom37 C-terminal domain Ctr PF04145.10 CDI85413.1 - 0.038 14.0 1.0 0.038 14.0 0.7 1.5 2 0 0 2 2 2 0 Ctr copper transporter family YfhO PF09586.5 CDI85413.1 - 0.05 11.6 2.2 0.052 11.5 1.5 1.0 1 0 0 1 1 1 0 Bacterial membrane protein YfhO Serinc PF03348.10 CDI85413.1 - 0.066 11.9 3.1 0.066 11.9 2.1 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) FAM176 PF14851.1 CDI85413.1 - 0.1 12.2 3.2 0.16 11.6 2.2 1.3 1 0 0 1 1 1 0 FAM176 family OATP PF03137.15 CDI85413.1 - 0.13 10.3 3.4 0.15 10.0 2.4 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family AAA_23 PF13476.1 CDI85413.1 - 0.17 12.2 11.4 0.18 12.1 7.9 1.2 1 0 0 1 1 1 0 AAA domain DUF4512 PF14975.1 CDI85413.1 - 0.21 12.4 1.7 0.23 12.2 0.3 1.8 2 0 0 2 2 1 0 Domain of unknown function (DUF4512) DUF3357 PF11837.3 CDI85413.1 - 0.28 11.0 5.1 0.19 11.5 1.8 2.0 2 1 0 2 2 2 0 Domain of unknown function (DUF3357) Folate_carrier PF01770.13 CDI85413.1 - 0.29 9.5 4.8 0.37 9.2 3.4 1.1 1 0 0 1 1 1 0 Reduced folate carrier Med15 PF09606.5 CDI85413.1 - 0.4 8.8 32.1 0.49 8.5 22.2 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Herpes_glycop PF01528.11 CDI85413.1 - 0.44 9.2 2.2 0.68 8.5 1.5 1.3 1 1 0 1 1 1 0 Herpesvirus glycoprotein M Peroxin-13_N PF04088.8 CDI85413.1 - 0.83 9.5 5.6 1.2 9.0 3.9 1.2 1 0 0 1 1 1 0 Peroxin 13, N-terminal region IncA PF04156.9 CDI85413.1 - 1.4 8.4 23.3 2.4 7.7 16.1 1.4 1 0 0 1 1 1 0 IncA protein DUF4446 PF14584.1 CDI85413.1 - 1.4 8.7 10.0 0.61 9.9 5.4 1.4 2 0 0 2 2 1 0 Protein of unknown function (DUF4446) DUF2232 PF09991.4 CDI85413.1 - 1.5 7.7 9.1 2.1 7.2 6.3 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) DUF3464 PF11947.3 CDI85413.1 - 1.8 8.0 4.9 2.7 7.4 2.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3464) DUF2149 PF09919.4 CDI85413.1 - 2.6 8.1 7.7 4.1 7.5 5.3 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2149) PEX11 PF05648.9 CDI85413.1 - 3.5 6.8 12.4 25 4.0 0.0 2.1 1 1 1 2 2 2 0 Peroxisomal biogenesis factor 11 (PEX11) DUF2946 PF11162.3 CDI85413.1 - 3.8 7.7 10.6 1 9.5 1.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2946) SHR3_chaperone PF08229.6 CDI85413.1 - 4.1 6.2 13.1 6 5.7 9.1 1.3 1 0 0 1 1 1 0 ER membrane protein SH3 DUF106 PF01956.11 CDI85413.1 - 4.4 6.8 9.1 6.1 6.3 6.3 1.2 1 0 0 1 1 1 0 Integral membrane protein DUF106 Endonuc_Holl PF10107.4 CDI85413.1 - 5 6.8 11.8 9 5.9 8.2 1.4 1 0 0 1 1 1 0 Endonuclease related to archaeal Holliday junction resolvase DUF1427 PF07235.6 CDI85413.1 - 6.5 6.9 7.3 3.6 7.7 3.4 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1427) Anoctamin PF04547.7 CDI85413.1 - 8.9 4.8 8.5 9.6 4.7 5.9 1.1 1 0 0 1 1 1 0 Calcium-activated chloride channel N6_N4_Mtase PF01555.13 CDI85414.1 - 7.1 6.0 7.0 3.4 7.0 0.3 2.1 2 0 0 2 2 2 0 DNA methylase Ycf1 PF05758.7 CDI85414.1 - 9 3.8 22.4 0.26 8.9 4.7 2.0 2 0 0 2 2 2 0 Ycf1 PBP1_TM PF14812.1 CDI85415.1 - 0.0051 17.0 1.3 0.0069 16.6 0.9 1.2 1 0 0 1 1 1 1 Transmembrane domain of transglycosylase PBP1 at N-terminal Serinc PF03348.10 CDI85415.1 - 0.33 9.5 6.4 0.34 9.5 4.4 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) Pex14_N PF04695.8 CDI85415.1 - 0.52 10.3 11.2 0.68 9.9 7.8 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region AIF_C PF14721.1 CDI85415.1 - 0.78 9.9 3.8 0.9 9.7 2.7 1.2 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term SID-1_RNA_chan PF13965.1 CDI85415.1 - 0.8 7.7 8.5 0.82 7.7 5.9 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Ctr PF04145.10 CDI85415.1 - 1.2 9.1 5.1 1.3 9.0 3.6 1.1 1 0 0 1 1 1 0 Ctr copper transporter family Ribosomal_L6e PF01159.14 CDI85415.1 - 1.3 9.3 6.1 1.3 9.2 4.3 1.1 1 0 0 1 1 1 0 Ribosomal protein L6e TK PF00265.13 CDI85415.1 - 1.6 8.2 4.9 1.7 8.1 3.4 1.0 1 0 0 1 1 1 0 Thymidine kinase DUF1840 PF08895.6 CDI85415.1 - 3.1 7.8 10.4 3.7 7.6 7.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1840) DUF912 PF06024.7 CDI85415.1 - 4.4 7.4 10.3 12 5.9 7.1 1.7 1 1 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Zn_peptidase PF04228.8 CDI85415.1 - 4.5 6.4 10.5 4.7 6.3 7.3 1.0 1 0 0 1 1 1 0 Putative neutral zinc metallopeptidase DUF4483 PF14825.1 CDI85415.1 - 4.7 6.8 13.3 5.8 6.5 9.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4483) OATP PF03137.15 CDI85415.1 - 6.7 4.6 7.8 6.5 4.6 5.4 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family TMEM51 PF15345.1 CDI85415.1 - 8.4 6.0 11.5 9.6 5.8 8.0 1.1 1 0 0 1 1 1 0 Transmembrane protein 51 Ctr PF04145.10 CDI85416.1 - 0.0026 17.8 6.1 0.0081 16.2 4.3 1.9 1 1 0 1 1 1 1 Ctr copper transporter family Herpes_LMP2 PF07415.6 CDI85416.1 - 0.0044 15.6 2.7 0.0044 15.6 1.9 1.8 1 1 0 2 2 2 1 Gammaherpesvirus latent membrane protein (LMP2) protein Pex14_N PF04695.8 CDI85416.1 - 0.0049 16.9 9.5 0.0049 16.9 6.6 1.8 2 0 0 2 2 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region PAF-AH_p_II PF03403.8 CDI85416.1 - 0.029 12.6 0.3 0.038 12.2 0.2 1.1 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II TFIIA PF03153.8 CDI85416.1 - 0.093 12.6 16.5 0.11 12.3 11.4 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Zip PF02535.17 CDI85416.1 - 0.096 11.6 0.0 0.14 11.1 0.0 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter PAT1 PF09770.4 CDI85416.1 - 0.1 10.8 29.8 0.12 10.5 20.7 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF872 PF05915.7 CDI85416.1 - 0.1 12.4 0.1 0.24 11.2 0.0 1.6 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF872) Tetraspannin PF00335.15 CDI85416.1 - 0.11 11.7 0.1 0.11 11.7 0.0 1.6 2 0 0 2 2 2 0 Tetraspanin family ABC2_membrane_2 PF12679.2 CDI85416.1 - 0.35 9.6 5.5 4 6.2 4.3 1.9 1 1 1 2 2 2 0 ABC-2 family transporter protein Serinc PF03348.10 CDI85416.1 - 0.93 8.1 5.9 0.41 9.3 2.2 1.6 1 1 1 2 2 2 0 Serine incorporator (Serinc) E1-E2_ATPase PF00122.15 CDI85418.1 - 2.1e-64 216.7 2.4 3.7e-63 212.6 0.8 2.4 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 CDI85418.1 - 7.2e-52 175.5 1.9 1.7e-51 174.3 1.3 1.7 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 CDI85418.1 - 8.2e-32 111.3 0.1 3.4e-30 106.0 0.0 2.8 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 CDI85418.1 - 2.9e-21 75.2 0.0 5.9e-21 74.2 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 CDI85418.1 - 3.5e-20 71.2 0.1 1.4e-19 69.3 0.0 2.0 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 CDI85418.1 - 5e-15 56.1 0.0 3e-14 53.6 0.0 2.3 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 CDI85418.1 - 1.2e-05 25.0 0.5 6.8e-05 22.5 0.4 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.1 CDI85418.1 - 0.09 12.6 0.0 0.35 10.7 0.0 2.0 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Tim54 PF11711.3 CDI85419.1 - 0.011 14.3 0.0 0.014 13.9 0.0 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 MSC PF09402.5 CDI85419.1 - 0.021 13.5 0.1 0.03 13.0 0.1 1.2 1 0 0 1 1 1 0 Man1-Src1p-C-terminal domain Sigma_reg_N PF13800.1 CDI85419.1 - 0.022 14.7 0.2 0.034 14.1 0.1 1.3 1 0 0 1 1 1 0 Sigma factor regulator N-terminal Inh PF02974.9 CDI85419.1 - 0.059 12.9 0.0 0.095 12.2 0.0 1.4 1 0 0 1 1 1 0 Protease inhibitor Inh DUF3609 PF12259.3 CDI85419.1 - 0.11 11.0 0.0 0.14 10.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3609) DUF4359 PF14271.1 CDI85419.1 - 0.12 12.7 0.2 16 5.9 0.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4359) tRNA-synt_His PF13393.1 CDI85420.1 - 8.6 5.3 8.1 10 5.0 5.6 1.0 1 0 0 1 1 1 0 Histidyl-tRNA synthetase CAF-1_p150 PF11600.3 CDI85421.1 - 0.0041 16.5 30.4 0.0052 16.1 21.1 1.1 1 0 0 1 1 1 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal SprA-related PF12118.3 CDI85421.1 - 0.33 10.2 46.9 0.45 9.7 32.5 1.2 1 0 0 1 1 1 0 SprA-related family Med15 PF09606.5 CDI85421.1 - 1.1 7.4 54.1 1.1 7.3 37.5 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF4540 PF15073.1 CDI85421.1 - 1.5 9.4 5.4 1.8 9.1 2.5 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4540) RAP1 PF07218.6 CDI85421.1 - 2.4 6.1 6.2 2.4 6.1 4.3 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) SOBP PF15279.1 CDI85421.1 - 3 8.1 26.3 3.4 7.9 18.2 1.0 1 0 0 1 1 1 0 Sine oculis-binding protein DUF3451 PF11933.3 CDI85421.1 - 3.1 7.5 23.6 12 5.6 16.4 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF3451) DUF2052 PF09747.4 CDI85421.1 - 4 7.3 25.9 4.9 7.0 18.0 1.1 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) PAT1 PF09770.4 CDI85421.1 - 7 4.7 43.2 7.7 4.6 30.0 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Macoilin PF09726.4 CDI85421.1 - 10 4.2 26.0 15 3.7 18.0 1.2 1 0 0 1 1 1 0 Transmembrane protein Spt20 PF12090.3 CDI85422.1 - 0.0014 18.0 3.1 0.12 11.6 0.3 2.2 2 0 0 2 2 2 2 Spt20 family Suf PF05843.9 CDI85422.1 - 0.059 13.1 5.9 0.085 12.5 0.7 2.3 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) FimP PF09766.4 CDI85422.1 - 2.8 6.9 14.8 0.6 9.1 3.5 2.1 2 0 0 2 2 2 0 Fms-interacting protein Med15 PF09606.5 CDI85422.1 - 2.8 6.0 49.6 0.011 13.9 12.8 2.4 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal RAB3GAP2_N PF14655.1 CDI85422.1 - 3.4 6.5 14.6 0.21 10.5 2.2 2.4 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus PNRC PF15365.1 CDI85423.1 - 0.31 11.0 3.9 9.8 6.2 1.7 2.1 2 0 0 2 2 2 0 Proline-rich nuclear receptor coactivator Pap_E4 PF02711.9 CDI85424.1 - 0.04 14.7 13.1 0.81 10.5 3.3 2.4 2 0 0 2 2 2 0 E4 protein CD20 PF04103.10 CDI85424.1 - 0.75 9.7 10.1 1 9.2 0.4 2.7 1 1 0 2 2 2 0 CD20-like family Spore_YhcN_YlaJ PF09580.5 CDI85424.1 - 0.79 9.8 16.0 1.5 8.9 3.3 2.1 2 0 0 2 2 2 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) Glyco_transf_8C PF08437.5 CDI85424.1 - 1.9 8.5 15.7 2.6 8.1 1.8 3.8 3 1 1 4 4 4 0 Glycosyl transferase family 8 C-terminal Spt5_N PF11942.3 CDI85424.1 - 3.4 8.3 14.9 0.27 11.8 2.7 2.5 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal FimP PF09766.4 CDI85424.1 - 4.6 6.2 34.1 0.81 8.6 7.2 2.1 2 0 0 2 2 2 0 Fms-interacting protein Draxin PF15550.1 CDI85424.1 - 6.5 6.3 20.5 11 5.5 14.2 1.3 1 0 0 1 1 1 0 Draxin DUF3357 PF11837.3 CDI85424.1 - 6.5 6.6 14.1 4 7.3 1.3 3.5 1 1 3 4 4 4 0 Domain of unknown function (DUF3357) MCR_alpha PF02249.12 CDI85425.1 - 1.7 8.6 8.0 2.9 7.8 2.3 2.5 2 0 0 2 2 2 0 Methyl-coenzyme M reductase alpha subunit, C-terminal domain Peptidase_M3_N PF08439.5 CDI85425.1 - 3.2 7.8 10.0 0.094 12.7 1.5 2.5 2 1 0 2 2 2 0 Oligopeptidase F AAA_23 PF13476.1 CDI85425.1 - 7.8 6.7 29.9 0.21 11.9 5.8 2.2 2 0 0 2 2 2 0 AAA domain Prog_receptor PF02161.10 CDI85426.1 - 0.0082 15.0 6.4 0.0092 14.8 4.4 1.0 1 0 0 1 1 1 1 Progesterone receptor Prothymosin PF03247.9 CDI85426.1 - 0.071 13.2 20.8 0.08 13.0 14.4 1.1 1 0 0 1 1 1 0 Prothymosin/parathymosin family BSP_II PF05432.6 CDI85426.1 - 0.15 11.2 15.7 0.17 11.1 10.9 1.1 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) VID27 PF08553.5 CDI85426.1 - 0.21 9.7 6.6 0.21 9.7 4.5 1.0 1 0 0 1 1 1 0 VID27 cytoplasmic protein Spore_coat_CotO PF14153.1 CDI85426.1 - 0.22 10.9 6.7 0.22 10.9 4.7 1.1 1 0 0 1 1 1 0 Spore coat protein CotO TRAP_alpha PF03896.11 CDI85426.1 - 0.34 9.8 5.0 0.35 9.8 3.5 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit FAM176 PF14851.1 CDI85426.1 - 0.56 9.8 3.9 0.6 9.7 2.7 1.1 1 0 0 1 1 1 0 FAM176 family DUF1510 PF07423.6 CDI85426.1 - 0.66 9.3 8.0 0.69 9.2 5.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Ribosomal_60s PF00428.14 CDI85426.1 - 0.69 10.3 16.7 1.1 9.7 11.6 1.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein Sigma70_ner PF04546.8 CDI85426.1 - 0.72 9.4 10.6 0.74 9.3 7.4 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region Nucleoplasmin PF03066.10 CDI85426.1 - 0.9 9.0 10.9 1.1 8.7 7.6 1.2 1 0 0 1 1 1 0 Nucleoplasmin PRP21_like_P PF12230.3 CDI85426.1 - 1.1 8.7 6.7 1.2 8.6 4.7 1.0 1 0 0 1 1 1 0 Pre-mRNA splicing factor PRP21 like protein YqfQ PF14181.1 CDI85426.1 - 1.1 9.2 6.4 1.3 9.0 4.4 1.1 1 0 0 1 1 1 0 YqfQ-like protein Tim54 PF11711.3 CDI85426.1 - 1.2 7.6 4.9 1.2 7.6 3.4 1.0 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DUF2890 PF11081.3 CDI85426.1 - 1.2 9.1 12.4 1.3 8.9 8.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) Plasmodium_Vir PF05795.6 CDI85426.1 - 1.5 7.9 3.4 1.5 7.9 2.3 1.0 1 0 0 1 1 1 0 Plasmodium vivax Vir protein DUF3381 PF11861.3 CDI85426.1 - 1.6 8.2 8.0 1.6 8.1 5.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) CobT PF06213.7 CDI85426.1 - 2.4 7.2 11.4 2.3 7.2 7.9 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Nop14 PF04147.7 CDI85426.1 - 3.4 5.4 12.3 3.6 5.3 8.6 1.0 1 0 0 1 1 1 0 Nop14-like family Usp PF00582.21 CDI85426.1 - 3.5 7.8 5.7 3.8 7.6 4.0 1.1 1 0 0 1 1 1 0 Universal stress protein family Menin PF05053.8 CDI85426.1 - 3.9 5.5 5.7 4.3 5.3 3.9 1.0 1 0 0 1 1 1 0 Menin Pox_Ag35 PF03286.9 CDI85426.1 - 4.9 6.6 7.7 5.2 6.5 5.3 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein CDC45 PF02724.9 CDI85426.1 - 5.1 5.0 7.5 5.2 4.9 5.2 1.0 1 0 0 1 1 1 0 CDC45-like protein DUF2457 PF10446.4 CDI85426.1 - 5.2 5.6 10.6 5 5.7 7.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Paf1 PF03985.8 CDI85426.1 - 5.4 5.6 12.3 5.3 5.6 8.6 1.0 1 0 0 1 1 1 0 Paf1 DUF3306 PF11748.3 CDI85426.1 - 6.7 7.4 7.4 7.3 7.2 5.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3306) Daxx PF03344.10 CDI85426.1 - 6.8 5.0 15.0 7 5.0 10.4 1.0 1 0 0 1 1 1 0 Daxx Family HSP90 PF00183.13 CDI85426.1 - 7.6 4.7 9.2 7.1 4.9 6.3 1.0 1 0 0 1 1 1 0 Hsp90 protein Merozoite_SPAM PF07133.6 CDI85426.1 - 8.2 6.2 17.3 9.3 6.1 12.0 1.1 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) Spc97_Spc98 PF04130.8 CDI85429.1 - 4e-19 68.3 57.2 1.1e-14 53.7 29.4 4.6 2 2 1 3 3 3 2 Spc97 / Spc98 family Ribosomal_60s PF00428.14 CDI85429.1 - 0.0019 18.5 13.9 0.0019 18.5 9.7 12.2 11 3 0 11 11 11 3 60s Acidic ribosomal protein FimP PF09766.4 CDI85431.1 - 0.01 14.9 8.7 0.01 14.9 6.0 4.0 3 1 1 4 4 4 0 Fms-interacting protein Spt20 PF12090.3 CDI85432.1 - 0.012 14.9 0.5 0.012 14.9 0.4 2.2 2 0 0 2 2 2 0 Spt20 family DUF4557 PF15101.1 CDI85432.1 - 0.086 12.6 17.3 0.13 12.1 3.9 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4557) Activator_LAG-3 PF11498.3 CDI85432.1 - 0.21 10.2 31.5 0.093 11.4 12.3 2.6 2 0 0 2 2 2 0 Transcriptional activator LAG-3 PRP38_assoc PF12871.2 CDI85433.1 - 0.088 13.3 84.2 2.4e+02 2.3 58.3 2.2 1 1 0 1 1 1 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term Macoilin PF09726.4 CDI85433.1 - 0.13 10.4 21.1 0.14 10.3 14.6 1.0 1 0 0 1 1 1 0 Transmembrane protein MIP-T3 PF10243.4 CDI85433.1 - 0.32 9.4 41.2 0.36 9.2 28.6 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 SR-25 PF10500.4 CDI85433.1 - 0.49 9.8 52.1 0.78 9.1 36.0 1.4 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein Period_C PF12114.3 CDI85433.1 - 0.74 9.3 22.2 0.9 9.1 15.4 1.2 1 0 0 1 1 1 0 Period protein 2/3C-terminal region SprA-related PF12118.3 CDI85433.1 - 1.8 7.8 20.0 2 7.6 13.9 1.0 1 0 0 1 1 1 0 SprA-related family DUF2217 PF10265.4 CDI85433.1 - 2.7 6.6 11.9 2.7 6.6 8.2 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) CAF-1_p150 PF11600.3 CDI85433.1 - 2.8 7.2 38.3 3.6 6.9 26.5 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Rtf2 PF04641.7 CDI85433.1 - 3 6.9 16.9 4.3 6.4 11.7 1.4 1 0 0 1 1 1 0 Rtf2 RING-finger DHHW PF14286.1 CDI85433.1 - 4 6.6 10.3 4.5 6.4 7.2 1.1 1 0 0 1 1 1 0 DHHW protein FLO_LFY PF01698.11 CDI85433.1 - 9.2 5.0 23.8 11 4.7 16.5 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein FimP PF09766.4 CDI85434.1 - 0.13 11.2 27.7 0.055 12.5 0.4 2.1 2 0 0 2 2 2 0 Fms-interacting protein FAM176 PF14851.1 CDI85434.1 - 0.42 10.2 8.4 8.9 5.9 0.0 2.4 2 0 0 2 2 2 0 FAM176 family Otopetrin PF03189.8 CDI85434.1 - 1.1 8.1 4.9 1.5 7.7 3.4 1.2 1 0 0 1 1 1 0 Otopetrin Septin PF00735.13 CDI85434.1 - 2.1 7.3 8.9 0.15 11.0 0.2 2.2 2 0 0 2 2 2 0 Septin Band_3_cyto PF07565.8 CDI85434.1 - 3.7 6.9 18.5 1.8 8.0 7.3 2.1 2 0 0 2 2 2 0 Band 3 cytoplasmic domain DUF1510 PF07423.6 CDI85434.1 - 4 6.7 17.6 5.2 6.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) Hid1 PF12722.2 CDI85434.1 - 5.1 4.6 13.4 3.8 5.0 6.5 1.9 2 0 0 2 2 2 0 High-temperature-induced dauer-formation protein Ribosomal_60s PF00428.14 CDI85434.1 - 9.8 6.6 36.5 1.5 9.2 8.3 2.6 3 0 0 3 3 3 0 60s Acidic ribosomal protein Rtf2 PF04641.7 CDI85435.1 - 5.1 6.2 27.7 5.6 6.0 19.2 1.0 1 0 0 1 1 1 0 Rtf2 RING-finger YqfQ PF14181.1 CDI85435.1 - 10 6.1 30.8 13 5.7 21.3 1.2 1 0 0 1 1 1 0 YqfQ-like protein zf-U1 PF06220.7 CDI85436.1 - 0.00038 19.9 0.5 0.00038 19.9 0.4 2.4 2 0 0 2 2 2 1 U1 zinc finger WW PF00397.21 CDI85436.1 - 0.0011 18.8 0.9 0.0027 17.5 0.0 2.1 2 0 0 2 2 2 1 WW domain Peptidase_M24 PF00557.19 CDI85437.1 - 1.6e-33 116.0 0.0 3.1e-33 115.1 0.0 1.5 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.13 CDI85437.1 - 1.1e-22 80.9 0.0 2.5e-17 63.5 0.0 2.8 2 0 0 2 2 2 2 Creatinase/Prolidase N-terminal domain EGF_3 PF12947.2 CDI85438.1 - 0.029 14.3 40.4 0.89 9.5 1.7 7.9 7 0 0 7 7 7 0 EGF domain cEGF PF12662.2 CDI85438.1 - 1.7 8.3 34.4 0.38 10.4 1.3 6.7 6 1 0 6 6 6 0 Complement Clr-like EGF-like PapD-like PF14874.1 CDI85439.1 - 9.6e-21 73.6 3.1 0.015 15.2 0.0 14.0 17 0 0 17 17 17 3 Flagellar-associated PapD-like Motile_Sperm PF00635.21 CDI85439.1 - 1.6e-13 50.2 0.7 0.3 10.7 0.0 10.7 13 0 0 13 13 13 2 MSP (Major sperm protein) domain FixG_C PF11614.3 CDI85439.1 - 1.1e-07 32.0 0.1 0.37 10.9 0.0 7.0 7 0 0 7 7 7 2 IG-like fold at C-terminal of FixG, putative oxidoreductase MYCBPAP PF14646.1 CDI85439.1 - 0.006 15.3 0.7 13 4.3 0.0 5.5 6 1 1 7 7 7 1 MYCBP-associated protein family AIP3 PF03915.8 CDI85439.1 - 0.93 8.3 0.3 1.6 7.5 0.2 1.2 1 0 0 1 1 1 0 Actin interacting protein 3 Amidohydro_3 PF07969.6 CDI85439.1 - 1.9 7.6 0.0 3.2 6.8 0.0 1.2 1 0 0 1 1 1 0 Amidohydrolase family ATP-synt_C PF00137.16 CDI85440.1 - 4.8e-32 109.6 22.3 1.8e-18 66.2 6.5 3.0 3 0 0 3 3 3 2 ATP synthase subunit C IMCp PF12314.3 CDI85441.1 - 3.6e-07 30.2 19.0 3.6e-07 30.2 13.1 4.2 1 1 2 3 3 3 2 Inner membrane complex protein ParA PF10609.4 CDI85442.1 - 2.5e-29 100.9 0.2 5.2e-29 99.9 0.2 1.5 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 CDI85442.1 - 1.9e-16 60.0 0.0 2.9e-16 59.4 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain DUF59 PF01883.14 CDI85442.1 - 5e-14 52.0 0.0 1.4e-13 50.6 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function DUF59 AAA_31 PF13614.1 CDI85442.1 - 3.6e-10 40.0 0.1 4.9e-09 36.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain MipZ PF09140.6 CDI85442.1 - 5e-06 25.7 0.0 1e-05 24.7 0.0 1.5 2 0 0 2 2 2 1 ATPase MipZ DUF971 PF06155.7 CDI85442.1 - 6.8e-06 26.4 0.0 1.6e-05 25.2 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF971) ArsA_ATPase PF02374.10 CDI85442.1 - 0.0028 16.7 0.7 0.21 10.5 0.2 2.2 2 0 0 2 2 2 1 Anion-transporting ATPase VirC1 PF07015.6 CDI85442.1 - 0.0057 15.7 0.1 0.0097 15.0 0.1 1.3 1 0 0 1 1 1 1 VirC1 protein APS_kinase PF01583.15 CDI85442.1 - 0.03 13.9 0.0 0.058 13.0 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase ArgK PF03308.11 CDI85442.1 - 0.11 11.2 0.1 0.18 10.5 0.0 1.2 1 0 0 1 1 1 0 ArgK protein SRP54 PF00448.17 CDI85442.1 - 0.14 11.6 0.0 0.22 10.9 0.0 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain NTP_transf_5 PF14907.1 CDI85443.1 - 0.051 12.9 0.0 0.051 12.9 0.0 2.0 2 0 0 2 2 2 0 Uncharacterised nucleotidyltransferase Sec20 PF03908.8 CDI85443.1 - 0.36 10.5 4.1 0.71 9.6 2.9 1.4 1 0 0 1 1 1 0 Sec20 V_ATPase_I PF01496.14 CDI85443.1 - 0.91 7.2 5.9 1.1 7.0 4.1 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family OmpH PF03938.9 CDI85443.1 - 1.4 8.8 13.2 2.8 7.8 9.2 1.5 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF972 PF06156.8 CDI85443.1 - 1.6 9.1 13.3 0.36 11.1 6.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF972) malic PF00390.14 CDI85444.1 - 0.11 12.0 0.0 11 5.5 0.0 2.2 2 0 0 2 2 2 0 Malic enzyme, N-terminal domain DUF4163 PF13739.1 CDI85444.1 - 0.12 13.2 0.0 22 5.9 0.0 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4163) TFIIA PF03153.8 CDI85444.1 - 5.6 6.7 11.4 2.6 7.8 3.0 2.6 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Utp14 PF04615.8 CDI85446.1 - 0.0013 16.9 31.3 0.0016 16.7 21.7 1.1 1 0 0 1 1 1 1 Utp14 protein Daxx PF03344.10 CDI85446.1 - 0.59 8.5 36.5 0.77 8.1 25.3 1.1 1 0 0 1 1 1 0 Daxx Family PLRV_ORF5 PF01690.12 CDI85446.1 - 1.7 7.6 32.9 2.2 7.3 22.8 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein SR-25 PF10500.4 CDI85447.1 - 0.0054 16.2 6.9 0.0054 16.2 4.8 3.2 2 1 1 3 3 3 2 Nuclear RNA-splicing-associated protein HK97-gp10_like PF04883.7 CDI85448.1 - 6.8 7.7 7.9 1e+02 3.9 5.5 2.5 1 1 0 1 1 1 0 Bacteriophage HK97-gp10, putative tail-component YtxH PF12732.2 CDI85449.1 - 0.00053 20.3 28.6 1.5e+04 -3.9 19.8 3.5 1 1 0 1 1 1 0 YtxH-like protein DUF883 PF05957.8 CDI85449.1 - 0.0034 17.7 28.2 1.4 9.3 10.2 3.1 1 1 2 3 3 3 3 Bacterial protein of unknown function (DUF883) CAP160 PF07918.6 CDI85449.1 - 0.049 13.2 1.7 0.049 13.2 1.2 3.5 5 0 0 5 5 5 0 CAP160 repeat Poxvirus_B22R PF04395.7 CDI85449.1 - 2.3 7.6 7.1 6.4 6.2 4.9 1.7 1 1 0 1 1 1 0 Poxvirus B22R protein RAP1 PF07218.6 CDI85451.1 - 1.2 7.1 3.8 2.3 6.2 2.6 1.4 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) CwfJ_C_1 PF04677.10 CDI85452.1 - 3.4e-26 91.2 0.0 6.7e-26 90.3 0.0 1.5 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.9 CDI85452.1 - 1.5e-10 41.4 0.0 1.5e-10 41.4 0.0 2.8 3 0 0 3 3 3 1 Protein similar to CwfJ C-terminus 2 RRM_6 PF14259.1 CDI85452.1 - 2.1e-07 30.7 0.0 1.3e-06 28.2 0.0 2.4 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CDI85452.1 - 3.2e-06 26.6 0.0 9.1e-06 25.2 0.0 1.9 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CDI85452.1 - 0.0026 17.5 0.2 0.012 15.4 0.0 2.2 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Peptidase_S49_N PF08496.5 CDI85452.1 - 0.28 10.9 3.4 3.8 7.2 0.4 2.5 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Ank_2 PF12796.2 CDI85453.1 - 1.2e-31 108.8 0.7 4.9e-11 42.8 0.5 3.5 3 0 0 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 CDI85453.1 - 9.4e-30 100.9 4.9 2.1e-05 24.0 0.1 5.4 5 0 0 5 5 5 5 Ankyrin repeat Ank_4 PF13637.1 CDI85453.1 - 3.6e-24 84.6 0.7 2e-08 34.5 0.0 3.4 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 CDI85453.1 - 3e-17 60.9 0.4 0.025 14.7 0.0 5.5 5 0 0 5 5 5 5 Ankyrin repeat Ank_5 PF13857.1 CDI85453.1 - 4.7e-11 42.5 13.1 0.00065 19.8 0.1 5.8 4 2 2 6 6 6 5 Ankyrin repeats (many copies) MIP-T3 PF10243.4 CDI85453.1 - 6.3 5.1 59.1 0.46 8.9 29.7 2.5 2 1 0 2 2 2 0 Microtubule-binding protein MIP-T3 TMEM51 PF15345.1 CDI85454.1 - 0.0037 17.0 10.3 0.0047 16.6 7.1 1.0 1 0 0 1 1 1 1 Transmembrane protein 51 SID-1_RNA_chan PF13965.1 CDI85454.1 - 0.0098 14.1 2.8 0.0097 14.1 2.0 1.0 1 0 0 1 1 1 1 dsRNA-gated channel SID-1 KBP_C PF12309.3 CDI85454.1 - 0.011 14.6 13.5 0.013 14.4 9.3 1.0 1 0 0 1 1 1 0 KIF-1 binding protein C terminal DUF4366 PF14283.1 CDI85454.1 - 0.018 14.4 5.9 0.023 14.1 4.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) Zip PF02535.17 CDI85454.1 - 0.02 13.8 8.2 0.022 13.7 5.7 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter TRAP_alpha PF03896.11 CDI85454.1 - 0.023 13.6 1.8 0.032 13.2 1.3 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DUF4293 PF14126.1 CDI85454.1 - 0.065 13.1 1.1 0.08 12.8 0.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4293) FHIPEP PF00771.15 CDI85454.1 - 0.089 11.1 3.7 0.11 10.8 2.5 1.1 1 0 0 1 1 1 0 FHIPEP family DUF3260 PF11658.3 CDI85454.1 - 0.092 10.8 4.0 0.11 10.6 2.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3260) DUF2615 PF11027.3 CDI85454.1 - 0.095 12.6 1.9 0.16 11.9 1.3 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2615) Suc_Fer-like PF06999.7 CDI85454.1 - 0.098 12.6 4.8 0.11 12.5 3.3 1.0 1 0 0 1 1 1 0 Sucrase/ferredoxin-like Corona_nucleoca PF00937.13 CDI85454.1 - 0.099 11.5 18.5 0.12 11.3 12.8 1.0 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein ABC2_membrane_2 PF12679.2 CDI85454.1 - 0.14 10.9 0.2 0.17 10.7 0.1 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein Herpes_glycop PF01528.11 CDI85454.1 - 0.16 10.6 3.2 0.17 10.5 2.2 1.2 1 0 0 1 1 1 0 Herpesvirus glycoprotein M Ycf1 PF05758.7 CDI85454.1 - 0.18 9.5 8.8 0.18 9.5 6.1 1.0 1 0 0 1 1 1 0 Ycf1 SAGA-Tad1 PF12767.2 CDI85454.1 - 0.19 11.3 15.2 0.21 11.2 10.5 1.0 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit 60KD_IMP PF02096.15 CDI85454.1 - 0.21 11.2 6.0 0.23 11.1 4.2 1.2 1 0 0 1 1 1 0 60Kd inner membrane protein PBP_sp32 PF07222.7 CDI85454.1 - 0.21 10.7 17.5 0.25 10.4 12.1 1.1 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Herpes_env PF01673.13 CDI85454.1 - 0.26 9.8 5.5 0.25 9.8 3.8 1.1 1 0 0 1 1 1 0 Herpesvirus putative major envelope glycoprotein Raftlin PF15250.1 CDI85454.1 - 0.33 9.4 11.5 0.36 9.3 8.0 1.0 1 0 0 1 1 1 0 Raftlin Suf PF05843.9 CDI85454.1 - 0.34 10.6 14.7 0.42 10.2 10.2 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) BAF1_ABF1 PF04684.8 CDI85454.1 - 0.4 9.4 24.6 0.38 9.5 17.1 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor DUF2149 PF09919.4 CDI85454.1 - 0.42 10.7 5.2 0.59 10.2 3.6 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2149) Bap31 PF05529.7 CDI85454.1 - 0.44 9.9 9.3 0.5 9.8 6.5 1.2 1 1 0 1 1 1 0 B-cell receptor-associated protein 31-like RBP_receptor PF14752.1 CDI85454.1 - 0.46 8.7 4.3 0.58 8.4 3.0 1.1 1 0 0 1 1 1 0 Retinol binding protein receptor SHR3_chaperone PF08229.6 CDI85454.1 - 0.47 9.3 9.4 0.51 9.2 6.5 1.2 1 0 0 1 1 1 0 ER membrane protein SH3 Fe_bilin_red PF05996.7 CDI85454.1 - 0.54 9.7 12.7 0.61 9.5 8.8 1.1 1 0 0 1 1 1 0 Ferredoxin-dependent bilin reductase GRP PF07172.6 CDI85454.1 - 0.58 10.6 4.5 0.56 10.7 2.2 1.7 1 1 0 1 1 1 0 Glycine rich protein family Med15 PF09606.5 CDI85454.1 - 0.74 7.9 26.6 0.74 7.9 18.4 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Spore_YhcN_YlaJ PF09580.5 CDI85454.1 - 0.77 9.8 6.5 0.82 9.7 4.5 1.2 1 0 0 1 1 1 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) DUF1183 PF06682.7 CDI85454.1 - 0.89 9.1 9.1 1.5 8.3 6.3 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1183) FAM176 PF14851.1 CDI85454.1 - 1.1 8.9 10.4 0.5 10.0 5.4 1.6 1 1 1 2 2 2 0 FAM176 family FPN1 PF06963.7 CDI85454.1 - 1.2 7.4 5.6 1.5 7.1 3.9 1.1 1 0 0 1 1 1 0 Ferroportin1 (FPN1) DUF3357 PF11837.3 CDI85454.1 - 1.3 8.9 8.2 4.7 7.1 5.7 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF3357) Endonuc_Holl PF10107.4 CDI85454.1 - 1.3 8.7 9.5 1.9 8.1 6.6 1.2 1 0 0 1 1 1 0 Endonuclease related to archaeal Holliday junction resolvase DUF3774 PF12609.3 CDI85454.1 - 1.4 9.8 15.2 0.3 11.9 1.6 2.1 2 0 0 2 2 2 0 Wound-induced protein DUF1510 PF07423.6 CDI85454.1 - 1.5 8.1 16.9 0.82 8.9 10.2 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1510) DUF4603 PF15376.1 CDI85454.1 - 1.7 5.7 12.6 1.9 5.5 8.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) FLO_LFY PF01698.11 CDI85454.1 - 1.9 7.2 11.0 2.4 6.9 7.6 1.2 1 0 0 1 1 1 0 Floricaula / Leafy protein AUX_IAA PF02309.11 CDI85454.1 - 1.9 8.1 9.7 2.3 7.8 6.7 1.1 1 0 0 1 1 1 0 AUX/IAA family Secretin_N_2 PF07655.8 CDI85454.1 - 2.2 8.7 11.8 1 9.7 1.7 2.1 2 0 0 2 2 2 0 Secretin N-terminal domain Otopetrin PF03189.8 CDI85454.1 - 2.9 6.8 9.7 3.1 6.7 6.2 1.4 1 1 1 2 2 2 0 Otopetrin Gag_spuma PF03276.9 CDI85454.1 - 2.9 6.1 19.3 3.8 5.7 13.4 1.2 1 0 0 1 1 1 0 Spumavirus gag protein Peroxin-13_N PF04088.8 CDI85454.1 - 3.1 7.7 9.1 2.4 8.0 4.9 1.6 1 1 1 2 2 2 0 Peroxin 13, N-terminal region SOBP PF15279.1 CDI85454.1 - 3.4 7.9 10.9 3.9 7.7 7.6 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein DUF4407 PF14362.1 CDI85454.1 - 3.6 6.4 9.0 3.6 6.4 6.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) BTV_NS2 PF04514.7 CDI85454.1 - 4.3 6.1 11.5 4.7 6.0 8.0 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Hid1 PF12722.2 CDI85454.1 - 7.6 4.0 14.6 9.1 3.8 10.1 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Oleosin PF01277.12 CDI85454.1 - 9.7 5.7 5.8 14 5.3 4.0 1.2 1 0 0 1 1 1 0 Oleosin RAP1 PF07218.6 CDI85455.1 - 6.2 4.7 3.9 11 3.9 2.7 1.5 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) BAF1_ABF1 PF04684.8 CDI85456.1 - 5.1e-05 22.3 24.1 6.3e-05 22.0 16.7 1.3 1 0 0 1 1 1 1 BAF1 / ABF1 chromatin reorganising factor Activator_LAG-3 PF11498.3 CDI85456.1 - 0.00087 18.1 32.0 0.0011 17.8 22.2 1.1 1 0 0 1 1 1 1 Transcriptional activator LAG-3 CAF-1_p150 PF11600.3 CDI85456.1 - 0.0033 16.8 19.9 0.0042 16.5 13.8 1.2 1 0 0 1 1 1 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal Med15 PF09606.5 CDI85456.1 - 0.0043 15.3 39.7 0.0054 15.0 27.5 1.1 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal FlxA PF14282.1 CDI85456.1 - 0.0099 15.8 47.5 0.015 15.2 32.9 1.3 1 0 0 1 1 1 1 FlxA-like protein Corona_nucleoca PF00937.13 CDI85456.1 - 0.019 13.8 15.1 0.021 13.7 10.5 1.2 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein POP1 PF06978.6 CDI85456.1 - 0.028 14.0 8.5 0.038 13.6 5.9 1.2 1 0 0 1 1 1 0 Ribonucleases P/MRP protein subunit POP1 SAGA-Tad1 PF12767.2 CDI85456.1 - 0.049 13.2 17.5 0.058 13.0 12.1 1.1 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit PAT1 PF09770.4 CDI85456.1 - 0.087 11.0 30.2 0.1 10.8 21.0 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SR-25 PF10500.4 CDI85456.1 - 0.09 12.2 29.4 0.29 10.5 20.4 1.7 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein Asp-B-Hydro_N PF05279.6 CDI85456.1 - 0.11 12.3 16.3 0.13 12.1 11.3 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region FimP PF09766.4 CDI85456.1 - 0.3 10.1 20.7 0.35 9.8 14.4 1.2 1 0 0 1 1 1 0 Fms-interacting protein SOBP PF15279.1 CDI85456.1 - 0.53 10.6 12.6 0.63 10.3 8.7 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein Herpes_UL87 PF03043.9 CDI85456.1 - 1 7.6 6.6 1.1 7.6 4.6 1.1 1 0 0 1 1 1 0 Herpesvirus UL87 family PPP4R2 PF09184.6 CDI85456.1 - 1.4 8.4 15.4 1.8 8.0 10.7 1.1 1 0 0 1 1 1 0 PPP4R2 DUF4175 PF13779.1 CDI85456.1 - 1.4 6.4 40.9 1.6 6.3 28.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) CDK5_activator PF03261.10 CDI85456.1 - 1.5 8.1 15.4 2.1 7.6 10.7 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein Hid1 PF12722.2 CDI85456.1 - 1.7 6.2 17.7 2 5.9 12.2 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Herpes_LMP2 PF07415.6 CDI85456.1 - 1.9 6.9 7.4 2.4 6.6 5.1 1.0 1 0 0 1 1 1 0 Gammaherpesvirus latent membrane protein (LMP2) protein Ycf1 PF05758.7 CDI85456.1 - 2.1 5.9 12.4 2.1 5.9 8.6 1.0 1 0 0 1 1 1 0 Ycf1 YjgP_YjgQ PF03739.9 CDI85456.1 - 2.5 6.7 4.3 2.8 6.6 3.0 1.1 1 0 0 1 1 1 0 Predicted permease YjgP/YjgQ family eIF-3_zeta PF05091.7 CDI85456.1 - 2.9 6.4 16.4 3.2 6.2 11.4 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Raftlin PF15250.1 CDI85456.1 - 3.1 6.2 13.9 3.6 6.0 9.6 1.1 1 0 0 1 1 1 0 Raftlin Mitofilin PF09731.4 CDI85456.1 - 3.2 6.2 27.8 5 5.6 19.2 1.4 1 1 0 1 1 1 0 Mitochondrial inner membrane protein 5_nucleotid PF05761.9 CDI85456.1 - 3.2 6.1 9.0 3.9 5.8 6.2 1.1 1 0 0 1 1 1 0 5' nucleotidase family Peptidase_S49_N PF08496.5 CDI85456.1 - 3.5 7.3 10.0 4.8 6.9 7.0 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Peptidase_U57 PF05582.7 CDI85456.1 - 3.8 6.4 9.1 4.7 6.0 6.3 1.2 1 0 0 1 1 1 0 YabG peptidase U57 PA26 PF04636.8 CDI85456.1 - 3.8 6.0 10.3 4.2 5.9 7.1 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) APG6 PF04111.7 CDI85456.1 - 4.9 6.0 16.5 5.5 5.9 11.4 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 Glyco_transf_15 PF01793.11 CDI85456.1 - 5.1 5.9 8.9 5.5 5.8 6.2 1.3 1 0 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase PBP_sp32 PF07222.7 CDI85456.1 - 8 5.5 21.2 11 5.1 14.7 1.2 1 0 0 1 1 1 0 Proacrosin binding protein sp32 DUF1510 PF07423.6 CDI85457.1 - 0.24 10.7 45.2 0.3 10.4 31.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) SR-25 PF10500.4 CDI85458.1 - 0.0039 16.6 7.0 0.0046 16.4 4.8 1.2 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein FimP PF09766.4 CDI85458.1 - 0.0076 15.3 13.7 0.0094 15.0 9.5 1.1 1 0 0 1 1 1 1 Fms-interacting protein FLO_LFY PF01698.11 CDI85458.1 - 0.033 13.0 3.5 0.034 12.9 2.4 1.2 1 0 0 1 1 1 0 Floricaula / Leafy protein Suf PF05843.9 CDI85458.1 - 0.063 13.0 9.0 0.069 12.8 6.2 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) RAB3GAP2_N PF14655.1 CDI85458.1 - 0.078 11.9 7.4 0.081 11.9 5.1 1.2 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Activator_LAG-3 PF11498.3 CDI85458.1 - 0.1 11.3 28.9 0.12 11.0 20.0 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Spt20 PF12090.3 CDI85458.1 - 0.15 11.4 6.6 0.16 11.3 4.6 1.1 1 0 0 1 1 1 0 Spt20 family CDK5_activator PF03261.10 CDI85458.1 - 0.23 10.7 12.9 0.26 10.6 8.9 1.0 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein PAT1 PF09770.4 CDI85458.1 - 0.29 9.3 23.0 0.27 9.4 15.9 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Mnd1 PF03962.10 CDI85458.1 - 0.32 10.6 9.6 0.38 10.3 6.7 1.1 1 0 0 1 1 1 0 Mnd1 family Serinc PF03348.10 CDI85458.1 - 0.32 9.6 6.0 0.35 9.5 4.2 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) HD-ZIP_N PF04618.7 CDI85458.1 - 0.36 11.3 2.5 0.48 10.9 1.8 1.3 1 0 0 1 1 1 0 HD-ZIP protein N terminus DUF4557 PF15101.1 CDI85458.1 - 0.44 10.3 14.5 0.49 10.2 10.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) Cons_hypoth95 PF03602.10 CDI85458.1 - 0.45 9.8 5.4 0.6 9.4 3.7 1.1 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Hid1 PF12722.2 CDI85458.1 - 0.45 8.1 3.6 0.46 8.0 2.5 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Hist_deacetyl PF00850.14 CDI85458.1 - 0.48 9.6 7.3 0.6 9.3 5.0 1.3 1 0 0 1 1 1 0 Histone deacetylase domain DDHD PF02862.12 CDI85458.1 - 0.51 10.0 5.3 0.54 10.0 3.7 1.1 1 0 0 1 1 1 0 DDHD domain DivIC PF04977.10 CDI85458.1 - 0.76 9.3 12.3 1.2 8.6 8.6 1.3 1 0 0 1 1 1 0 Septum formation initiator Baculo_PP31 PF05311.6 CDI85458.1 - 0.83 8.8 5.5 0.92 8.7 3.8 1.1 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) MCPVI PF02993.9 CDI85458.1 - 1 9.4 11.5 1.3 9.1 7.9 1.2 1 0 0 1 1 1 0 Minor capsid protein VI UPF0560 PF10577.4 CDI85458.1 - 1.4 7.1 15.2 1.6 6.9 10.6 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 CD20 PF04103.10 CDI85458.1 - 1.8 8.4 6.6 0.91 9.4 2.9 1.8 1 1 0 1 1 1 0 CD20-like family DUF2232 PF09991.4 CDI85458.1 - 2 7.3 4.2 2.3 7.1 2.9 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) Shisa PF13908.1 CDI85458.1 - 3.5 7.7 12.3 3.9 7.6 8.5 1.3 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Hamartin PF04388.7 CDI85458.1 - 7.9 5.0 10.8 8.4 4.9 7.5 1.1 1 0 0 1 1 1 0 Hamartin protein Presenilin PF01080.12 CDI85458.1 - 9.2 4.9 6.7 10 4.8 4.6 1.2 1 0 0 1 1 1 0 Presenilin DUF2146 PF10220.4 CDI85458.1 - 9.3 4.0 11.7 10 3.9 8.1 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2146) EMP24_GP25L PF01105.19 CDI85460.1 - 1.3e-30 106.4 0.0 1.6e-30 106.1 0.0 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF4199 PF13858.1 CDI85460.1 - 0.064 13.1 0.6 0.1 12.5 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) Vma12 PF11712.3 CDI85460.1 - 0.083 12.5 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase EXS PF03124.9 CDI85462.1 - 8.7e-30 103.9 0.5 1.2e-29 103.4 0.3 1.2 1 0 0 1 1 1 1 EXS family SDH_alpha PF03313.10 CDI85462.1 - 0.0081 15.2 4.1 0.011 14.8 2.8 1.2 1 0 0 1 1 1 1 Serine dehydratase alpha chain Dapper PF15268.1 CDI85463.1 - 0.0021 16.9 13.8 0.0024 16.7 9.6 1.0 1 0 0 1 1 1 1 Dapper Ribosomal_60s PF00428.14 CDI85463.1 - 0.015 15.6 12.4 0.28 11.6 2.1 2.3 2 0 0 2 2 2 0 60s Acidic ribosomal protein Chorion_2 PF03964.10 CDI85463.1 - 0.066 13.7 11.7 0.066 13.7 2.6 2.3 2 0 0 2 2 2 0 Chorion family 2 PAT1 PF09770.4 CDI85463.1 - 0.079 11.2 25.2 0.085 11.0 17.4 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF4613 PF15390.1 CDI85463.1 - 0.11 10.7 8.2 0.13 10.4 5.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) DDRGK PF09756.4 CDI85463.1 - 0.95 8.8 9.3 1.1 8.6 6.4 1.1 1 0 0 1 1 1 0 DDRGK domain Shadoo PF14999.1 CDI85463.1 - 1.3 8.8 7.6 0.95 9.3 0.1 2.2 2 0 0 2 2 2 0 Shadow of prion protein, neuroprotective OmpH PF03938.9 CDI85463.1 - 1.8 8.5 31.9 2.7 7.8 22.1 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Med15 PF09606.5 CDI85463.1 - 1.8 6.6 37.7 2.3 6.3 26.1 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Adeno_VII PF03228.9 CDI85463.1 - 4.5 7.8 7.6 1.7 9.2 3.4 1.7 1 1 1 2 2 2 0 Adenoviral core protein VII Senescence_reg PF04520.8 CDI85463.1 - 4.6 7.7 6.9 7.3 7.0 4.8 1.2 1 0 0 1 1 1 0 Senescence regulator Hid1 PF12722.2 CDI85463.1 - 9.9 3.6 9.9 12 3.4 6.9 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Peripla_BP_3 PF13377.1 CDI85464.1 - 8e-06 25.9 1.2 1.1e-05 25.5 0.8 1.3 1 0 0 1 1 1 1 Periplasmic binding protein-like domain Nop14 PF04147.7 CDI85464.1 - 4.9e-05 21.4 21.2 5.4e-05 21.3 14.7 1.0 1 0 0 1 1 1 1 Nop14-like family SDA1 PF05285.7 CDI85464.1 - 0.0001 21.6 20.5 0.00012 21.5 14.2 1.1 1 0 0 1 1 1 1 SDA1 CDC45 PF02724.9 CDI85464.1 - 0.0003 18.9 22.5 0.00032 18.8 15.6 1.0 1 0 0 1 1 1 1 CDC45-like protein Spore_coat_CotO PF14153.1 CDI85464.1 - 0.00073 19.0 30.3 0.00096 18.6 21.0 1.2 1 0 0 1 1 1 1 Spore coat protein CotO SAPS PF04499.10 CDI85464.1 - 0.0051 15.5 19.2 0.0054 15.4 13.3 1.1 1 0 0 1 1 1 1 SIT4 phosphatase-associated protein DUF1510 PF07423.6 CDI85464.1 - 0.016 14.5 32.8 0.022 14.1 22.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Pox_Ag35 PF03286.9 CDI85464.1 - 0.02 14.4 19.1 0.028 13.9 13.3 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DHHW PF14286.1 CDI85464.1 - 0.024 13.9 17.2 0.027 13.7 11.9 1.1 1 0 0 1 1 1 0 DHHW protein DUF4045 PF13254.1 CDI85464.1 - 0.028 13.7 22.1 0.033 13.4 15.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) FLO_LFY PF01698.11 CDI85464.1 - 0.042 12.6 22.6 0.054 12.3 15.6 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein SPX PF03105.14 CDI85464.1 - 0.053 13.3 18.9 0.063 13.0 13.1 1.1 1 0 0 1 1 1 0 SPX domain Hid1 PF12722.2 CDI85464.1 - 0.094 10.3 27.2 0.11 10.2 18.9 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Ycf1 PF05758.7 CDI85464.1 - 0.12 10.0 28.1 0.14 9.8 19.5 1.0 1 0 0 1 1 1 0 Ycf1 Med19 PF10278.4 CDI85464.1 - 0.16 11.6 19.2 0.23 11.1 13.3 1.2 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 LMBR1 PF04791.11 CDI85464.1 - 0.21 10.1 10.8 0.26 9.8 7.5 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Dicty_REP PF05086.7 CDI85464.1 - 0.32 8.7 12.6 0.42 8.3 8.7 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Zip PF02535.17 CDI85464.1 - 0.34 9.8 11.2 0.5 9.3 7.7 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter Rtf2 PF04641.7 CDI85464.1 - 0.34 10.0 24.0 0.5 9.5 16.6 1.3 1 0 0 1 1 1 0 Rtf2 RING-finger NPR3 PF03666.8 CDI85464.1 - 0.35 9.3 24.2 0.57 8.6 16.8 1.3 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Utp14 PF04615.8 CDI85464.1 - 0.4 8.7 35.0 0.49 8.5 24.2 1.0 1 0 0 1 1 1 0 Utp14 protein AvrE PF11725.3 CDI85464.1 - 0.42 7.5 22.2 0.44 7.5 15.4 1.0 1 0 0 1 1 1 0 Pathogenicity factor DUF4175 PF13779.1 CDI85464.1 - 0.43 8.2 62.4 0.52 7.9 43.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Astro_capsid PF03115.9 CDI85464.1 - 0.44 8.7 13.6 0.49 8.6 9.4 1.0 1 0 0 1 1 1 0 Astrovirus capsid protein precursor Neur_chan_memb PF02932.11 CDI85464.1 - 0.48 10.2 15.1 0.55 10.0 10.5 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Vfa1 PF08432.5 CDI85464.1 - 0.55 10.2 28.2 0.76 9.7 19.5 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF2201_N PF13203.1 CDI85464.1 - 0.6 9.2 27.8 0.69 9.0 19.3 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain Raftlin PF15250.1 CDI85464.1 - 0.76 8.2 23.8 0.9 7.9 16.5 1.1 1 0 0 1 1 1 0 Raftlin Dapper PF15268.1 CDI85464.1 - 0.83 8.3 30.4 0.99 8.1 21.0 1.0 1 0 0 1 1 1 0 Dapper TT_ORF1 PF02956.9 CDI85464.1 - 0.84 8.0 11.5 0.94 7.8 8.0 1.1 1 0 0 1 1 1 0 TT viral orf 1 DUF966 PF06136.8 CDI85464.1 - 0.85 8.9 20.0 1.2 8.5 13.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF966) DUF4638 PF15472.1 CDI85464.1 - 0.87 9.1 15.1 1 8.8 10.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) PLRV_ORF5 PF01690.12 CDI85464.1 - 0.88 8.6 24.0 1 8.3 16.6 1.0 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein SAGA-Tad1 PF12767.2 CDI85464.1 - 1.1 8.9 25.2 1.4 8.5 17.5 1.2 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit Daxx PF03344.10 CDI85464.1 - 1.2 7.4 38.5 1.5 7.2 26.7 1.0 1 0 0 1 1 1 0 Daxx Family SET PF00856.23 CDI85464.1 - 1.3 9.3 3.8 1.9 8.7 2.7 1.4 1 0 0 1 1 1 0 SET domain GAGA_bind PF06217.7 CDI85464.1 - 1.3 8.9 21.7 1.4 8.8 15.1 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family TFIIA PF03153.8 CDI85464.1 - 1.3 8.8 39.3 1.6 8.5 27.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CENP-T PF15511.1 CDI85464.1 - 1.4 8.1 32.4 1.7 7.8 22.5 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T AUX_IAA PF02309.11 CDI85464.1 - 1.4 8.6 19.8 1.9 8.1 13.7 1.3 1 0 0 1 1 1 0 AUX/IAA family Herpes_env PF01673.13 CDI85464.1 - 1.4 7.3 13.8 2 6.8 9.6 1.3 1 0 0 1 1 1 0 Herpesvirus putative major envelope glycoprotein Caldesmon PF02029.10 CDI85464.1 - 1.9 6.8 30.6 2.4 6.5 21.2 1.1 1 0 0 1 1 1 0 Caldesmon Parvo_coat PF00740.13 CDI85464.1 - 2.2 7.1 23.7 2.6 6.9 16.4 1.1 1 0 0 1 1 1 0 Parvovirus coat protein VP2 FAM60A PF15396.1 CDI85464.1 - 2.2 7.9 20.7 3.1 7.5 14.3 1.1 1 0 0 1 1 1 0 Protein Family FAM60A Paf1 PF03985.8 CDI85464.1 - 2.3 6.8 39.0 3.2 6.4 27.1 1.2 1 0 0 1 1 1 0 Paf1 RR_TM4-6 PF06459.7 CDI85464.1 - 4.4 7.1 30.4 5.9 6.6 21.1 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF2126 PF09899.4 CDI85464.1 - 6 4.7 16.9 8.4 4.2 11.7 1.3 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) DDRGK PF09756.4 CDI85464.1 - 6.6 6.1 41.8 8.9 5.6 29.0 1.2 1 0 0 1 1 1 0 DDRGK domain MMR1 PF08505.5 CDI85464.1 - 8.2 6.3 31.6 10 6.1 21.9 1.1 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein YABBY PF04690.8 CDI85464.1 - 8.4 6.5 16.4 13 5.9 11.3 1.3 1 0 0 1 1 1 0 YABBY protein eIF-3_zeta PF05091.7 CDI85464.1 - 8.9 4.7 25.7 12 4.3 17.8 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF4647 PF15504.1 CDI85464.1 - 9.5 4.9 27.8 11 4.7 19.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4647) PAT1 PF09770.4 CDI85464.1 - 9.6 4.2 58.8 11 4.1 40.7 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 CRF1 PF10380.4 CDI85465.1 - 1 9.7 0.0 1 9.7 0.0 8.5 3 2 3 6 6 6 0 Transcription factor CRF1 Kelch_4 PF13418.1 CDI85466.1 - 3e-05 23.6 0.5 0.00029 20.5 0.2 2.8 3 0 0 3 3 3 1 Galactose oxidase, central domain Kelch_5 PF13854.1 CDI85466.1 - 3.1e-05 23.8 0.0 0.001 18.9 0.0 3.3 4 0 0 4 4 4 1 Kelch motif Kelch_3 PF13415.1 CDI85466.1 - 1 9.5 0.0 1 9.5 0.0 4.8 6 0 0 6 6 6 0 Galactose oxidase, central domain DUF1788 PF08747.6 CDI85467.1 - 0.0036 17.1 0.5 0.0085 15.9 0.3 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1788) SR-25 PF10500.4 CDI85467.1 - 0.0065 15.9 18.0 0.0065 15.9 12.5 2.2 1 1 1 2 2 2 1 Nuclear RNA-splicing-associated protein TRAP_alpha PF03896.11 CDI85467.1 - 0.0096 14.9 10.7 0.0096 14.9 7.4 2.0 2 1 0 2 2 2 1 Translocon-associated protein (TRAP), alpha subunit Serinc PF03348.10 CDI85467.1 - 0.0097 14.6 1.0 0.0097 14.6 0.7 2.8 1 1 0 2 2 2 1 Serine incorporator (Serinc) HTH_Tnp_Mu_1 PF02316.11 CDI85467.1 - 0.36 10.5 8.6 1.2 8.8 4.6 2.1 1 1 1 2 2 2 0 Mu DNA-binding domain RnfC_N PF13375.1 CDI85467.1 - 0.39 10.4 4.5 0.66 9.7 3.1 1.3 1 0 0 1 1 1 0 RnfC Barrel sandwich hybrid domain OAD_gamma PF04277.8 CDI85467.1 - 0.71 10.2 5.6 0.53 10.6 0.5 2.6 3 0 0 3 3 3 0 Oxaloacetate decarboxylase, gamma chain DNA_pol_viral_N PF00242.12 CDI85467.1 - 0.71 8.8 14.1 1.2 8.1 9.7 1.3 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain Herpes_UL87 PF03043.9 CDI85467.1 - 0.83 7.9 9.2 1 7.6 6.4 1.0 1 0 0 1 1 1 0 Herpesvirus UL87 family Med15 PF09606.5 CDI85467.1 - 5.2 5.1 47.9 6.4 4.8 33.2 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal BAF1_ABF1 PF04684.8 CDI85468.1 - 0.0016 17.3 19.9 0.002 17.0 13.8 1.1 1 0 0 1 1 1 1 BAF1 / ABF1 chromatin reorganising factor DUF2076 PF09849.4 CDI85468.1 - 0.0028 17.7 8.3 0.0036 17.4 5.7 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) DUF1129 PF06570.6 CDI85468.1 - 0.038 13.2 0.1 0.038 13.2 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) Med15 PF09606.5 CDI85468.1 - 0.078 11.1 20.4 0.08 11.1 14.1 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal PEHE PF15275.1 CDI85468.1 - 0.14 12.5 7.5 0.19 12.1 5.2 1.1 1 0 0 1 1 1 0 PEHE domain Band_3_cyto PF07565.8 CDI85468.1 - 0.19 11.1 3.1 0.25 10.8 2.1 1.3 1 0 0 1 1 1 0 Band 3 cytoplasmic domain OmpH PF03938.9 CDI85468.1 - 0.2 11.5 14.7 0.29 11.0 10.2 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) MAPEG PF01124.13 CDI85468.1 - 0.33 10.5 1.8 0.56 9.8 1.3 1.3 1 1 0 1 1 1 0 MAPEG family DUF4175 PF13779.1 CDI85468.1 - 0.6 7.7 16.7 0.68 7.5 11.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) DUF2852 PF11014.3 CDI85468.1 - 4.5 7.2 6.8 5 7.1 4.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2852) U79_P34 PF03064.11 CDI85468.1 - 5.1 6.5 8.8 0.51 9.8 0.4 2.0 2 0 0 2 2 2 0 HSV U79 / HCMV P34 APC_CDC26 PF10471.4 CDI85468.1 - 5.8 7.7 23.8 3.8 8.2 0.5 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit 1 Suf PF05843.9 CDI85468.1 - 7.9 6.1 12.6 8.4 6.0 8.3 1.3 1 1 0 1 1 1 0 Suppressor of forked protein (Suf) dsDNA_bind PF01984.15 CDI85468.1 - 9.6 6.2 20.9 9.2 6.3 12.3 2.0 2 0 0 2 2 2 0 Double-stranded DNA-binding domain Red1 PF07964.6 CDI85469.1 - 1.7 6.7 5.9 1.9 6.5 4.1 1.1 1 0 0 1 1 1 0 Rec10 / Red1 Nol1_Nop2_Fmu PF01189.12 CDI85470.1 - 6.8e-05 22.3 1.6 0.00016 21.1 1.4 1.4 2 0 0 2 2 2 1 NOL1/NOP2/sun family Ndc1_Nup PF09531.5 CDI85470.1 - 0.0068 14.8 5.4 0.0076 14.7 3.8 1.2 1 0 0 1 1 1 1 Nucleoporin protein Ndc1-Nup Ofd1_CTDD PF10637.4 CDI85470.1 - 0.007 15.5 2.5 0.0088 15.1 1.7 1.1 1 0 0 1 1 1 1 Oxoglutarate and iron-dependent oxygenase degradation C-term Sporozoite_P67 PF05642.6 CDI85470.1 - 0.0071 14.2 0.4 0.0073 14.2 0.3 1.0 1 0 0 1 1 1 1 Sporozoite P67 surface antigen DUF4245 PF14030.1 CDI85470.1 - 0.0079 15.9 0.4 0.011 15.4 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4245) CDK2AP PF09806.4 CDI85470.1 - 0.011 15.9 8.7 0.016 15.4 6.0 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein DUF572 PF04502.8 CDI85470.1 - 0.014 14.6 4.4 0.019 14.1 3.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) BAF1_ABF1 PF04684.8 CDI85470.1 - 0.016 14.1 8.2 0.025 13.4 5.7 1.3 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor CBF PF03914.12 CDI85470.1 - 0.018 14.4 0.5 0.025 14.0 0.3 1.1 1 0 0 1 1 1 0 CBF/Mak21 family PAT1 PF09770.4 CDI85470.1 - 0.038 12.2 13.0 0.036 12.3 9.0 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 FHIPEP PF00771.15 CDI85470.1 - 0.085 11.1 0.2 0.094 11.0 0.2 1.2 1 0 0 1 1 1 0 FHIPEP family Transposase_24 PF03004.9 CDI85470.1 - 0.1 12.4 0.3 0.1 12.4 0.2 2.1 2 0 0 2 2 2 0 Plant transposase (Ptta/En/Spm family) FCP1_C PF09309.5 CDI85470.1 - 0.11 11.7 5.4 0.22 10.8 3.8 1.4 1 0 0 1 1 1 0 FCP1, C-terminal DUF775 PF05603.7 CDI85470.1 - 0.14 11.6 8.9 0.084 12.3 1.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF775) MACPF PF01823.14 CDI85470.1 - 0.16 11.6 4.9 0.21 11.2 3.4 1.1 1 0 0 1 1 1 0 MAC/Perforin domain HlyD_2 PF12700.2 CDI85470.1 - 0.17 11.0 4.3 0.21 10.6 3.0 1.1 1 0 0 1 1 1 0 HlyD family secretion protein Presenilin PF01080.12 CDI85470.1 - 0.19 10.5 4.6 0.24 10.1 3.2 1.1 1 0 0 1 1 1 0 Presenilin Conotoxin PF02950.12 CDI85470.1 - 0.41 11.4 5.5 9.9 7.0 0.3 2.3 2 0 0 2 2 2 0 Conotoxin Neur_chan_memb PF02932.11 CDI85470.1 - 0.44 10.3 3.6 0.58 10.0 2.5 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region MDFI PF15316.1 CDI85470.1 - 0.5 10.3 5.7 0.75 9.7 4.0 1.2 1 0 0 1 1 1 0 MyoD family inhibitor DUF4175 PF13779.1 CDI85470.1 - 1.1 6.8 17.1 1.5 6.4 11.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) UPF0561 PF10573.4 CDI85470.1 - 1.3 8.9 5.7 1.9 8.3 4.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family UPF0561 DNA_pol_viral_N PF00242.12 CDI85470.1 - 1.4 7.8 10.6 1.8 7.5 7.3 1.1 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain Rxt3 PF08642.5 CDI85470.1 - 5.5 7.2 5.8 14 6.0 0.0 2.1 1 1 1 2 2 2 0 Histone deacetylation protein Rxt3 Tom22 PF04281.8 CDI85470.1 - 5.6 6.4 8.9 0.91 9.0 0.6 2.1 2 0 0 2 2 2 0 Mitochondrial import receptor subunit Tom22 Ribosomal_60s PF00428.14 CDI85471.1 - 0.00051 20.3 6.2 0.00051 20.3 4.3 27.4 19 6 6 26 26 26 4 60s Acidic ribosomal protein Spt20 PF12090.3 CDI85471.1 - 0.15 11.3 19.3 0.87 8.9 0.6 4.1 4 0 0 4 4 4 0 Spt20 family Serinc PF03348.10 CDI85471.1 - 8.3 5.0 16.1 0.32 9.6 0.3 4.0 3 0 0 3 3 3 0 Serine incorporator (Serinc) Ribosomal_60s PF00428.14 CDI85473.1 - 3 8.3 45.9 0.15 12.4 11.2 4.9 3 1 1 4 4 4 0 60s Acidic ribosomal protein Kinase-like PF14531.1 CDI85474.1 - 1.7e-06 27.1 0.0 4.1e-06 25.9 0.0 1.6 2 0 0 2 2 2 1 Kinase-like DUF755 PF05501.6 CDI85477.1 - 0.00094 19.2 25.0 0.00094 19.2 17.3 3.0 2 1 1 3 3 3 1 Domain of unknown function (DUF755) Mucin PF01456.12 CDI85477.1 - 0.018 14.7 1.6 0.018 14.7 1.1 2.4 2 0 0 2 2 2 0 Mucin-like glycoprotein Cons_hypoth698 PF03601.9 CDI85477.1 - 0.033 12.8 2.6 0.039 12.6 0.1 2.0 2 0 0 2 2 2 0 Conserved hypothetical protein 698 DUF1183 PF06682.7 CDI85477.1 - 0.46 10.0 24.0 6.5 6.2 16.6 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1183) DUF572 PF04502.8 CDI85477.1 - 0.84 8.7 31.7 1.3 8.1 22.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) Trp_oprn_chp PF09534.5 CDI85477.1 - 1.1 8.8 13.9 17 4.9 9.6 2.3 1 1 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF1510 PF07423.6 CDI85477.1 - 3.6 6.9 33.2 0.12 11.7 9.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1510) ETRAMP PF09716.5 CDI85477.1 - 4.3 7.3 0.0 4.3 7.3 0.0 3.4 3 2 0 3 3 3 0 Malarial early transcribed membrane protein (ETRAMP) Amidohydro_2 PF04909.9 CDI85479.1 - 0.0085 15.6 0.0 0.013 15.0 0.0 1.3 1 1 0 1 1 1 1 Amidohydrolase Macoilin PF09726.4 CDI85479.1 - 0.036 12.3 11.2 0.045 12.0 7.8 1.1 1 0 0 1 1 1 0 Transmembrane protein Hid1 PF12722.2 CDI85479.1 - 1.6 6.3 7.3 1.6 6.2 5.0 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein TFIIA PF03153.8 CDI85479.1 - 1.9 8.2 21.4 2.7 7.7 14.9 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit TMEM51 PF15345.1 CDI85479.1 - 2.8 7.5 8.5 3.1 7.4 5.2 1.6 2 0 0 2 2 2 0 Transmembrane protein 51 DUF966 PF06136.8 CDI85479.1 - 4 6.7 10.7 5.2 6.3 7.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Peptidase_S64 PF08192.6 CDI85479.1 - 4.2 5.5 9.4 5 5.3 6.5 1.2 1 0 0 1 1 1 0 Peptidase family S64 Apt1 PF10351.4 CDI85483.1 - 0.73 8.6 9.4 1.1 8.0 6.5 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain Secretin_N_2 PF07655.8 CDI85483.1 - 3.7 8.0 23.3 7.4 7.0 16.2 1.4 1 0 0 1 1 1 0 Secretin N-terminal domain Mito_fiss_reg PF05308.6 CDI85485.1 - 0.23 10.8 7.1 0.24 10.7 4.9 1.0 1 0 0 1 1 1 0 Mitochondrial fission regulator ERM PF00769.14 CDI85485.1 - 0.86 9.0 12.3 0.92 8.9 8.5 1.1 1 0 0 1 1 1 0 Ezrin/radixin/moesin family CAP_N PF01213.14 CDI85485.1 - 2.1 7.5 10.5 2.5 7.2 7.3 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal PPE PF00823.14 CDI85485.1 - 2.4 7.9 24.8 3.7 7.3 17.2 1.3 1 0 0 1 1 1 0 PPE family DUF3987 PF13148.1 CDI85485.1 - 2.4 6.6 9.8 2.6 6.5 6.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) HpaP PF09483.5 CDI85485.1 - 6.8 6.6 16.4 7.4 6.4 11.3 1.0 1 0 0 1 1 1 0 Type III secretion protein (HpaP) DUF1510 PF07423.6 CDI85487.1 - 5.3e-06 25.9 11.4 5.3e-06 25.9 7.9 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1510) Ycf1 PF05758.7 CDI85487.1 - 0.00021 19.1 0.9 0.00023 19.0 0.6 1.0 1 0 0 1 1 1 1 Ycf1 Suf PF05843.9 CDI85487.1 - 0.0028 17.4 5.0 0.0031 17.2 3.5 1.1 1 0 0 1 1 1 1 Suppressor of forked protein (Suf) DUF1183 PF06682.7 CDI85487.1 - 0.0079 15.8 3.9 0.0079 15.8 2.7 1.6 1 1 1 2 2 2 1 Protein of unknown function (DUF1183) TRAP_alpha PF03896.11 CDI85487.1 - 0.02 13.9 4.7 0.05 12.5 3.2 1.7 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DUF913 PF06025.7 CDI85487.1 - 0.027 13.2 9.0 0.035 12.8 6.2 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Pex24p PF06398.6 CDI85487.1 - 0.028 13.2 0.1 0.051 12.3 0.0 1.5 1 1 1 2 2 2 0 Integral peroxisomal membrane peroxin Mem_trans PF03547.13 CDI85487.1 - 0.13 10.4 8.5 0.23 9.7 5.9 1.4 1 1 0 1 1 1 0 Membrane transport protein DUF1980 PF09323.5 CDI85487.1 - 0.17 11.5 7.3 0.096 12.4 3.4 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF1980) Tetraspannin PF00335.15 CDI85487.1 - 0.36 10.0 12.8 0.04 13.1 5.1 2.1 1 1 0 2 2 2 0 Tetraspanin family FimP PF09766.4 CDI85487.1 - 0.6 9.1 22.4 0.69 8.9 15.5 1.0 1 0 0 1 1 1 0 Fms-interacting protein Calc_CGRP_IAPP PF00214.14 CDI85487.1 - 0.77 9.8 6.5 1.2 9.1 4.5 1.5 1 1 0 1 1 1 0 Calcitonin / CGRP / IAPP family DUF775 PF05603.7 CDI85487.1 - 2.5 7.5 12.8 4.6 6.6 8.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF775) DUF3381 PF11861.3 CDI85487.1 - 5.2 6.5 17.8 6.3 6.2 12.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) GNT-I PF03071.10 CDI85487.1 - 5.7 5.3 10.5 8.4 4.8 7.2 1.3 1 0 0 1 1 1 0 GNT-I family YfhO PF09586.5 CDI85487.1 - 5.8 4.7 13.4 7.9 4.3 9.3 1.4 1 1 0 1 1 1 0 Bacterial membrane protein YfhO Paf1 PF03985.8 CDI85487.1 - 8.4 5.0 18.5 9.8 4.7 12.8 1.0 1 0 0 1 1 1 0 Paf1 YABBY PF04690.8 CDI85487.1 - 8.9 6.5 9.1 1.9 8.7 4.3 1.5 1 1 0 1 1 1 0 YABBY protein Mcp5_PH PF12814.2 CDI85489.1 - 0.0046 16.8 2.3 0.0054 16.6 1.6 1.0 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology DUF3121 PF11319.3 CDI85489.1 - 0.14 11.6 6.6 0.16 11.4 4.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3121) RVP PF00077.15 CDI85489.1 - 0.5 10.3 2.6 0.57 10.1 1.8 1.0 1 0 0 1 1 1 0 Retroviral aspartyl protease Spin-Ssty PF02513.12 CDI85489.1 - 1.6 8.3 8.4 1.7 8.2 0.3 2.2 1 1 1 2 2 2 0 Spin/Ssty Family DUF2228 PF10228.4 CDI85489.1 - 2.1 7.8 6.2 2.1 7.8 4.3 1.0 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2228) DUSP PF06337.7 CDI85489.1 - 2.2 8.7 8.6 3.1 8.2 5.9 1.1 1 0 0 1 1 1 0 DUSP domain FKBP_N PF01346.13 CDI85489.1 - 2.3 8.2 14.2 2.9 7.9 9.8 1.1 1 0 0 1 1 1 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase SPT16 PF08644.6 CDI85489.1 - 2.9 7.7 9.8 3.6 7.4 6.8 1.0 1 0 0 1 1 1 0 FACT complex subunit (SPT16/CDC68) DBC1 PF14443.1 CDI85489.1 - 3.2 7.2 6.4 3.5 7.1 4.5 1.1 1 0 0 1 1 1 0 DBC1 Pinin_SDK_memA PF04696.8 CDI85489.1 - 3.8 7.1 14.1 4.3 6.9 9.8 1.1 1 0 0 1 1 1 0 pinin/SDK/memA/ protein conserved region RED_N PF07808.8 CDI85489.1 - 4.6 6.3 12.7 4.9 6.2 8.8 1.1 1 0 0 1 1 1 0 RED-like protein N-terminal region DUF2072 PF09845.4 CDI85489.1 - 4.8 7.1 6.0 5.4 6.9 4.1 1.1 1 0 0 1 1 1 0 Zn-ribbon containing protein (DUF2072) K_channel_TID PF07941.6 CDI85490.1 - 0.026 14.7 8.8 0.026 14.7 6.1 8.5 4 3 3 7 7 7 0 Potassium channel Kv1.4 tandem inactivation domain DUF1183 PF06682.7 CDI85491.1 - 0.063 12.8 0.1 0.09 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) DUF2763 PF10961.3 CDI85491.1 - 0.32 11.4 1.9 0.72 10.2 0.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2763) DUF1510 PF07423.6 CDI85492.1 - 0.26 10.6 11.1 0.0099 15.2 3.5 1.7 2 1 0 2 2 2 0 Protein of unknown function (DUF1510) Trypan_PARP PF05887.6 CDI85494.1 - 0.91 9.3 28.5 1.1 9.0 19.8 1.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) CDC45 PF02724.9 CDI85494.1 - 8.8 4.2 31.4 9.1 4.1 21.8 1.0 1 0 0 1 1 1 0 CDC45-like protein DUF572 PF04502.8 CDI85495.1 - 0.085 12.0 29.7 0.11 11.6 20.6 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF4175 PF13779.1 CDI85495.1 - 0.48 8.0 29.5 0.57 7.8 20.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Hid1 PF12722.2 CDI85495.1 - 0.59 7.7 20.0 0.75 7.3 13.8 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF4407 PF14362.1 CDI85495.1 - 7.3 5.4 13.2 9.3 5.0 9.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Herpes_env PF01673.13 CDI85495.1 - 9.4 4.6 11.5 12 4.3 8.0 1.1 1 0 0 1 1 1 0 Herpesvirus putative major envelope glycoprotein BRK PF07533.11 CDI85496.1 - 0.089 12.2 0.1 0.68 9.4 0.0 2.1 2 0 0 2 2 2 0 BRK domain TMEM51 PF15345.1 CDI85497.1 - 0.0017 18.0 7.7 0.0031 17.2 5.3 1.5 1 0 0 1 1 1 1 Transmembrane protein 51 Mem_trans PF03547.13 CDI85497.1 - 0.009 14.3 1.6 0.013 13.8 1.1 1.3 1 0 0 1 1 1 1 Membrane transport protein Neur_chan_memb PF02932.11 CDI85497.1 - 0.14 12.0 1.4 0.14 12.0 1.0 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Mitofilin PF09731.4 CDI85497.1 - 0.16 10.5 18.7 0.2 10.2 13.0 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Med15 PF09606.5 CDI85497.1 - 0.17 10.0 43.1 0.22 9.6 29.9 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Pex16 PF08610.5 CDI85497.1 - 0.21 10.5 8.6 0.25 10.3 6.0 1.1 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) DUF4175 PF13779.1 CDI85497.1 - 0.25 8.9 25.2 0.35 8.5 17.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Conotoxin PF02950.12 CDI85497.1 - 0.42 11.4 7.6 1.2 9.9 5.3 1.9 1 1 0 1 1 1 0 Conotoxin Band_3_cyto PF07565.8 CDI85497.1 - 0.45 9.9 6.2 0.54 9.7 4.3 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain DUF4647 PF15504.1 CDI85497.1 - 0.45 9.3 12.3 0.62 8.8 8.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4647) LCD1 PF09798.4 CDI85497.1 - 0.45 8.4 7.3 0.49 8.3 5.1 1.0 1 0 0 1 1 1 0 DNA damage checkpoint protein Hid1 PF12722.2 CDI85497.1 - 0.55 7.8 8.0 0.64 7.6 5.5 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein FAM176 PF14851.1 CDI85497.1 - 0.58 9.8 2.4 0.81 9.3 1.7 1.2 1 0 0 1 1 1 0 FAM176 family DUF966 PF06136.8 CDI85497.1 - 0.6 9.4 12.1 0.82 9.0 8.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF966) NST1 PF13945.1 CDI85497.1 - 0.78 9.7 13.6 1.2 9.1 9.4 1.3 1 0 0 1 1 1 0 Salt tolerance down-regulator Draxin PF15550.1 CDI85497.1 - 2.2 7.8 9.5 3.5 7.1 6.6 1.3 1 0 0 1 1 1 0 Draxin Peptidase_S64 PF08192.6 CDI85497.1 - 3.2 5.9 8.2 3.8 5.7 5.7 1.1 1 0 0 1 1 1 0 Peptidase family S64 Rtf2 PF04641.7 CDI85497.1 - 3.6 6.7 11.4 4.9 6.2 7.9 1.2 1 0 0 1 1 1 0 Rtf2 RING-finger Plasmodium_Vir PF05795.6 CDI85497.1 - 3.6 6.6 4.2 4.3 6.4 2.9 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein RED_N PF07808.8 CDI85497.1 - 4.1 6.5 15.1 5.9 6.0 10.5 1.2 1 0 0 1 1 1 0 RED-like protein N-terminal region MRP-S31 PF15433.1 CDI85497.1 - 7.9 5.8 14.4 13 5.0 10.0 1.3 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 DUF4557 PF15101.1 CDI85497.1 - 8.1 6.2 21.5 13 5.5 14.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) Paramyxo_ncap PF00973.14 CDI85497.1 - 8.4 4.9 7.5 10 4.6 5.2 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein DUF2828 PF11443.3 CDI85497.1 - 10 4.2 9.3 12 3.9 6.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) DUF2126 PF09899.4 CDI85499.1 - 0.027 12.5 4.8 0.034 12.2 3.3 1.1 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) Svf1 PF08622.5 CDI85499.1 - 0.04 12.8 0.7 0.05 12.5 0.5 1.1 1 0 0 1 1 1 0 Svf1-like LCD1 PF09798.4 CDI85499.1 - 0.33 8.8 6.7 0.36 8.7 4.7 1.1 1 0 0 1 1 1 0 DNA damage checkpoint protein Herpes_ori_bp PF02399.10 CDI85499.1 - 0.39 8.5 6.8 0.44 8.4 4.7 1.0 1 0 0 1 1 1 0 Origin of replication binding protein DUF3573 PF12097.3 CDI85499.1 - 0.48 8.9 6.0 0.56 8.7 4.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) DUF3584 PF12128.3 CDI85499.1 - 2.7 5.1 15.9 2.8 5.1 11.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Herpes_UL87 PF03043.9 CDI85499.1 - 8.5 4.6 8.0 9.4 4.4 5.5 1.1 1 0 0 1 1 1 0 Herpesvirus UL87 family FHIPEP PF00771.15 CDI85500.1 - 0.00013 20.4 0.6 0.00015 20.2 0.4 1.1 1 0 0 1 1 1 1 FHIPEP family DDHD PF02862.12 CDI85500.1 - 0.015 15.0 4.3 0.015 15.0 3.0 1.1 1 0 0 1 1 1 0 DDHD domain Spore_coat_CotO PF14153.1 CDI85500.1 - 0.11 11.9 16.7 0.13 11.6 11.6 1.1 1 0 0 1 1 1 0 Spore coat protein CotO DUF1510 PF07423.6 CDI85500.1 - 0.13 11.6 16.2 0.15 11.4 11.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) RNA_pol_Rpc4 PF05132.9 CDI85500.1 - 0.13 12.2 7.1 0.18 11.7 4.9 1.4 1 0 0 1 1 1 0 RNA polymerase III RPC4 Ycf1 PF05758.7 CDI85500.1 - 0.15 9.7 9.4 0.17 9.6 6.5 1.0 1 0 0 1 1 1 0 Ycf1 Raftlin PF15250.1 CDI85500.1 - 0.15 10.5 3.0 0.14 10.6 2.1 1.0 1 0 0 1 1 1 0 Raftlin HsdM_N PF12161.3 CDI85500.1 - 0.17 12.3 4.1 0.27 11.6 2.8 1.4 1 0 0 1 1 1 0 HsdM N-terminal domain Zip PF02535.17 CDI85500.1 - 0.18 10.7 1.2 0.18 10.7 0.8 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter CDC45 PF02724.9 CDI85500.1 - 0.21 9.5 13.0 0.23 9.4 9.0 1.0 1 0 0 1 1 1 0 CDC45-like protein Pox_Ag35 PF03286.9 CDI85500.1 - 0.21 11.1 10.6 0.23 10.9 7.3 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DUF572 PF04502.8 CDI85500.1 - 0.27 10.4 11.8 0.31 10.1 8.2 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Sporozoite_P67 PF05642.6 CDI85500.1 - 0.32 8.8 4.9 0.33 8.7 3.4 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen BTV_NS2 PF04514.7 CDI85500.1 - 0.32 9.8 8.0 0.33 9.8 5.6 1.0 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 RR_TM4-6 PF06459.7 CDI85500.1 - 0.37 10.6 12.6 0.38 10.6 8.7 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF913 PF06025.7 CDI85500.1 - 0.4 9.3 3.4 0.4 9.3 2.3 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) HDOD PF08668.7 CDI85500.1 - 0.47 9.6 4.7 0.31 10.3 2.4 1.3 1 1 0 1 1 1 0 HDOD domain Nop14 PF04147.7 CDI85500.1 - 0.49 8.2 22.9 0.54 8.1 15.9 1.0 1 0 0 1 1 1 0 Nop14-like family RP-C_C PF11800.3 CDI85500.1 - 0.56 9.8 9.0 0.71 9.5 6.3 1.2 1 0 0 1 1 1 0 Replication protein C C-terminal region Sigma70_ner PF04546.8 CDI85500.1 - 0.58 9.7 17.6 0.77 9.3 12.2 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region DUF2201_N PF13203.1 CDI85500.1 - 0.59 9.2 4.3 0.71 8.9 3.0 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain TRAP_alpha PF03896.11 CDI85500.1 - 0.67 8.9 15.8 0.74 8.7 11.0 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DUF2457 PF10446.4 CDI85500.1 - 0.69 8.5 22.6 0.84 8.2 15.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) CPSF100_C PF13299.1 CDI85500.1 - 0.79 9.8 5.7 0.95 9.6 3.9 1.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal NARP1 PF12569.3 CDI85500.1 - 0.83 8.3 9.1 0.88 8.2 6.3 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Tom37_C PF11801.3 CDI85500.1 - 0.83 9.4 5.0 1.1 9.1 3.5 1.2 1 0 0 1 1 1 0 Tom37 C-terminal domain RNA_pol_3_Rpc31 PF11705.3 CDI85500.1 - 0.85 9.5 19.2 1.1 9.1 13.3 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 TSA PF03249.8 CDI85500.1 - 0.97 7.8 5.4 1.2 7.5 3.7 1.1 1 0 0 1 1 1 0 Type specific antigen Rhabdo_ncap PF00945.13 CDI85500.1 - 1 7.8 4.8 1.1 7.7 3.3 1.1 1 0 0 1 1 1 0 Rhabdovirus nucleocapsid protein Daxx PF03344.10 CDI85500.1 - 1.1 7.7 25.8 1.2 7.5 17.9 1.1 1 0 0 1 1 1 0 Daxx Family Pilt PF15453.1 CDI85500.1 - 1.2 8.7 9.0 1.3 8.6 6.2 1.1 1 0 0 1 1 1 0 Protein incorporated later into Tight Junctions NPR3 PF03666.8 CDI85500.1 - 1.3 7.4 4.7 1.4 7.4 3.2 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Paf1 PF03985.8 CDI85500.1 - 1.3 7.6 24.2 1.5 7.4 16.8 1.0 1 0 0 1 1 1 0 Paf1 SMN PF06003.7 CDI85500.1 - 1.5 7.9 4.4 1.6 7.7 3.0 1.1 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) RskA PF10099.4 CDI85500.1 - 1.7 8.3 9.2 9.7 5.8 6.4 1.9 1 1 0 1 1 1 0 Anti-sigma-K factor rskA SDA1 PF05285.7 CDI85500.1 - 1.7 7.8 20.4 1.9 7.7 14.1 1.1 1 0 0 1 1 1 0 SDA1 GCIP PF13324.1 CDI85500.1 - 1.7 7.8 6.5 1.8 7.7 4.5 1.0 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting Astro_capsid PF03115.9 CDI85500.1 - 1.9 6.6 4.6 1.7 6.7 3.2 1.0 1 0 0 1 1 1 0 Astrovirus capsid protein precursor BUD22 PF09073.5 CDI85500.1 - 2 7.3 16.9 2.4 7.1 11.7 1.1 1 0 0 1 1 1 0 BUD22 Plasmodium_Vir PF05795.6 CDI85500.1 - 2.5 7.2 6.0 2.7 7.1 4.2 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein DUF2722 PF10846.3 CDI85500.1 - 2.7 6.9 7.7 3.3 6.6 5.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) SAPS PF04499.10 CDI85500.1 - 2.7 6.5 7.7 2.8 6.4 5.3 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein RNA_polI_A34 PF08208.6 CDI85500.1 - 3.7 7.1 15.2 4.4 6.9 10.5 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 CENP-T PF15511.1 CDI85500.1 - 4.2 6.5 14.3 5 6.2 9.9 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T DUF3381 PF11861.3 CDI85500.1 - 4.5 6.7 21.7 5.9 6.3 15.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) Tim54 PF11711.3 CDI85500.1 - 6.4 5.2 12.8 7.1 5.1 8.8 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 VID27 PF08553.5 CDI85500.1 - 7.8 4.5 19.4 8.7 4.4 13.4 1.0 1 0 0 1 1 1 0 VID27 cytoplasmic protein Pkinase PF00069.20 CDI85502.1 - 2.8e-14 52.9 0.0 3.6e-11 42.7 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CDI85502.1 - 0.0056 15.7 1.1 0.59 9.1 0.1 2.4 2 1 0 2 2 2 2 Protein tyrosine kinase CBP4 PF07960.6 CDI85502.1 - 0.54 9.8 16.5 1.3 8.5 1.6 2.5 2 0 0 2 2 2 0 CBP4 Med15 PF09606.5 CDI85502.1 - 1.3 7.1 42.3 0.24 9.5 3.8 2.5 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal FCP1_C PF09309.5 CDI85502.1 - 1.9 7.7 23.3 5.8 6.1 12.6 2.8 2 0 0 2 2 2 0 FCP1, C-terminal Alpha_adaptinC2 PF02883.15 CDI85503.1 - 2e-14 53.8 0.0 1.2e-12 48.1 0.0 2.6 1 1 0 1 1 1 1 Adaptin C-terminal domain Adaptin_N PF01602.15 CDI85503.1 - 8.3e-10 37.5 1.0 1.5e-08 33.4 0.7 2.0 1 1 0 1 1 1 1 Adaptin N terminal region Adaptin_N PF01602.15 CDI85504.1 - 2.9e-23 82.0 0.1 2.9e-23 82.0 0.1 1.5 2 0 0 2 2 2 1 Adaptin N terminal region HEAT_2 PF13646.1 CDI85504.1 - 0.58 10.4 7.1 3.7 7.8 2.7 2.9 1 1 1 2 2 2 0 HEAT repeats GAGA_bind PF06217.7 CDI85504.1 - 0.95 9.3 23.7 1.2 8.9 16.4 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family Neur_chan_memb PF02932.11 CDI85504.1 - 1.5 8.6 19.3 2.9 7.7 13.4 1.6 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF755 PF05501.6 CDI85505.1 - 0.013 15.6 7.9 0.017 15.2 5.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF755) Codanin-1_C PF15296.1 CDI85505.1 - 0.55 10.1 6.9 0.82 9.5 4.8 1.6 1 1 0 1 1 1 0 Codanin-1 C-terminus DUF2217 PF10265.4 CDI85505.1 - 0.89 8.2 9.1 0.93 8.1 6.3 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) DUF812 PF05667.6 CDI85505.1 - 1.4 7.3 11.9 1.7 7.0 8.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF812) FGF-BP1 PF06473.7 CDI85505.1 - 2.5 7.6 7.1 2.7 7.4 4.9 1.1 1 0 0 1 1 1 0 FGF binding protein 1 (FGF-BP1) Podoplanin PF05808.6 CDI85505.1 - 2.6 7.5 6.6 3.2 7.3 4.6 1.2 1 0 0 1 1 1 0 Podoplanin DUF1387 PF07139.6 CDI85505.1 - 3.1 7.3 12.0 3.6 7.1 8.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) Pex14_N PF04695.8 CDI85505.1 - 4 7.4 18.9 8.1 6.4 13.1 1.5 1 1 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF966 PF06136.8 CDI85505.1 - 5.1 6.4 10.6 5.5 6.3 7.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) DUF2146 PF10220.4 CDI85505.1 - 5.1 4.9 7.1 5.3 4.8 4.9 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2146) PIH1 PF08190.7 CDI85505.1 - 5.4 6.3 8.0 5.9 6.2 5.5 1.1 1 0 0 1 1 1 0 pre-RNA processing PIH1/Nop17 CDC27 PF09507.5 CDI85505.1 - 8 5.5 16.6 8.6 5.4 11.5 1.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 DNA_pol_viral_N PF00242.12 CDI85505.1 - 9.8 5.0 9.8 10 5.0 6.8 1.0 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain EF1_GNE PF00736.14 CDI85506.1 - 5.6e-09 35.5 13.9 1.6e-08 34.1 0.2 2.8 2 1 1 3 3 3 2 EF-1 guanine nucleotide exchange domain Ran-binding PF05508.6 CDI85506.1 - 0.014 14.3 3.3 0.016 14.0 2.3 1.0 1 0 0 1 1 1 0 RanGTP-binding protein PBP1_TM PF14812.1 CDI85506.1 - 0.13 12.5 8.4 1.4 9.2 0.3 2.2 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DHO_dh PF01180.16 CDI85506.1 - 0.16 10.8 1.4 0.2 10.6 0.9 1.1 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase DNA_ligase_A_C PF04679.10 CDI85506.1 - 0.67 10.3 2.8 2 8.8 1.9 1.9 1 1 0 1 1 1 0 ATP dependent DNA ligase C terminal region Daxx PF03344.10 CDI85506.1 - 3.3 6.0 12.4 3.9 5.8 8.6 1.0 1 0 0 1 1 1 0 Daxx Family DOR PF14839.1 CDI85507.1 - 5.1 6.7 13.8 0.052 13.2 4.1 1.7 2 1 0 2 2 2 0 DOR family DUF4490 PF14892.1 CDI85508.1 - 1.5e-08 34.2 0.0 2e-08 33.8 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4490) CDC45 PF02724.9 CDI85509.1 - 3.5 5.5 7.6 4.1 5.3 5.3 1.1 1 0 0 1 1 1 0 CDC45-like protein SRP72 PF08492.7 CDI85511.1 - 0.043 14.1 0.8 0.043 14.1 0.5 2.6 2 1 0 2 2 2 0 SRP72 RNA-binding domain PAS_4 PF08448.5 CDI85511.1 - 1.1 9.3 7.1 0.87 9.6 0.1 2.3 2 1 0 2 2 2 0 PAS fold DUF3628 PF12300.3 CDI85511.1 - 1.2 9.1 14.1 0.48 10.4 7.9 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3628) EphA2_TM PF14575.1 CDI85511.1 - 3.9 7.9 7.4 23 5.4 0.0 2.3 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain TRAUB PF08164.7 CDI85511.1 - 3.9 7.6 10.1 0.4 10.8 0.3 2.3 2 0 0 2 2 2 0 Apoptosis-antagonizing transcription factor, C-terminal FYDLN_acid PF09538.5 CDI85511.1 - 5.7 7.5 7.2 19 5.8 0.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) DUF4658 PF15555.1 CDI85511.1 - 6.8 6.5 6.9 0.17 11.7 0.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4658) eIF_4EBP PF05456.6 CDI85511.1 - 7.6 6.2 16.8 2.4 7.8 6.0 2.2 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) Ribosomal_60s PF00428.14 CDI85511.1 - 7.7 6.9 26.8 14 6.1 11.9 3.1 3 0 0 3 3 3 0 60s Acidic ribosomal protein SOBP PF15279.1 CDI85511.1 - 8.7 6.6 21.2 11 6.3 14.7 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein Consortin_C PF15281.1 CDI85511.1 - 8.7 5.8 11.2 0.18 11.2 1.0 2.1 2 0 0 2 2 2 0 Consortin C-terminus SseC PF04888.7 CDI85512.1 - 6.4e-07 29.0 43.9 6.4e-07 29.0 30.4 2.5 2 1 0 2 2 2 1 Secretion system effector C (SseC) like family Med15 PF09606.5 CDI85512.1 - 1.5e-05 23.4 26.7 1.5e-05 23.4 18.5 2.9 3 0 0 3 3 3 1 ARC105 or Med15 subunit of Mediator complex non-fungal FimP PF09766.4 CDI85512.1 - 0.067 12.2 10.5 0.17 10.9 6.6 1.8 2 0 0 2 2 2 0 Fms-interacting protein Spt20 PF12090.3 CDI85512.1 - 0.33 10.2 9.1 0.043 13.1 3.5 1.6 2 0 0 2 2 2 0 Spt20 family Nop53 PF07767.6 CDI85512.1 - 0.42 9.5 12.2 0.67 8.8 8.4 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) ERF PF04404.7 CDI85512.1 - 0.63 9.5 14.8 1.3 8.4 10.3 1.5 1 0 0 1 1 1 0 ERF superfamily LCD1 PF09798.4 CDI85512.1 - 1.2 7.0 6.6 1.6 6.6 4.6 1.1 1 0 0 1 1 1 0 DNA damage checkpoint protein Corona_nucleoca PF00937.13 CDI85512.1 - 1.8 7.4 28.7 1.3 7.9 12.7 2.3 2 0 0 2 2 2 0 Coronavirus nucleocapsid protein SR-25 PF10500.4 CDI85513.1 - 0.00013 21.4 10.7 0.00013 21.4 7.4 6.9 5 2 0 6 6 6 2 Nuclear RNA-splicing-associated protein Med15 PF09606.5 CDI85513.1 - 0.0058 14.9 112.9 0.035 12.3 27.0 3.2 3 0 0 3 3 3 3 ARC105 or Med15 subunit of Mediator complex non-fungal zf-DHHC PF01529.15 CDI85513.1 - 0.15 11.4 12.2 1.2 8.5 0.1 3.3 3 0 0 3 3 3 0 DHHC palmitoyltransferase PRP1_N PF06424.7 CDI85513.1 - 4.3 7.6 33.5 0.27 11.5 2.7 4.1 4 0 0 4 4 4 0 PRP1 splicing factor, N-terminal CAF-1_p150 PF11600.3 CDI85514.1 - 8.4e-05 22.0 27.7 0.00011 21.7 19.2 1.0 1 0 0 1 1 1 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal Activator_LAG-3 PF11498.3 CDI85514.1 - 0.011 14.5 38.2 0.014 14.1 26.5 1.3 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Corona_nucleoca PF00937.13 CDI85514.1 - 0.018 14.0 27.0 0.021 13.8 18.7 1.0 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein DDRGK PF09756.4 CDI85514.1 - 0.032 13.6 16.4 0.035 13.5 11.4 1.2 1 0 0 1 1 1 0 DDRGK domain SprA-related PF12118.3 CDI85514.1 - 0.046 13.0 36.3 0.056 12.7 25.2 1.1 1 0 0 1 1 1 0 SprA-related family SOBP PF15279.1 CDI85514.1 - 0.15 12.4 20.9 0.16 12.3 14.5 1.0 1 0 0 1 1 1 0 Sine oculis-binding protein PP2C_2 PF13672.1 CDI85514.1 - 0.19 11.1 9.1 0.22 10.8 6.3 1.1 1 0 0 1 1 1 0 Protein phosphatase 2C Med15 PF09606.5 CDI85514.1 - 0.19 9.8 36.5 0.2 9.8 25.3 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF4175 PF13779.1 CDI85514.1 - 0.32 8.6 33.5 0.32 8.6 23.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) PBP_sp32 PF07222.7 CDI85514.1 - 0.34 10.0 22.6 0.42 9.7 15.7 1.1 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Dicty_REP PF05086.7 CDI85514.1 - 0.45 8.2 18.4 0.51 8.0 12.8 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Hex_IIIa PF02455.11 CDI85514.1 - 0.45 9.1 16.8 0.49 9.0 11.6 1.0 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) MOR2-PAG1_N PF14222.1 CDI85514.1 - 0.47 9.0 8.3 0.53 8.9 5.7 1.1 1 0 0 1 1 1 0 Cell morphogenesis N-terminal Peptidase_S49_N PF08496.5 CDI85514.1 - 0.51 10.1 11.7 0.6 9.9 8.1 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal XRN_N PF03159.13 CDI85514.1 - 0.6 9.4 7.1 0.66 9.3 4.9 1.2 1 0 0 1 1 1 0 XRN 5'-3' exonuclease N-terminus Raftlin PF15250.1 CDI85514.1 - 0.69 8.3 19.2 0.79 8.1 13.3 1.0 1 0 0 1 1 1 0 Raftlin FLO_LFY PF01698.11 CDI85514.1 - 0.81 8.4 19.4 0.87 8.3 13.5 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein Hamartin PF04388.7 CDI85514.1 - 1.2 7.7 17.8 1.3 7.6 12.4 1.0 1 0 0 1 1 1 0 Hamartin protein PAT1 PF09770.4 CDI85514.1 - 1.6 6.9 33.1 1.6 6.8 22.9 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 eIF3_subunit PF08597.5 CDI85514.1 - 2.2 7.7 16.6 2.5 7.5 11.5 1.1 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit KfrA_N PF11740.3 CDI85514.1 - 2.5 8.5 24.9 3.3 8.1 17.2 1.1 1 0 0 1 1 1 0 Plasmid replication region DNA-binding N-term Peptidase_U57 PF05582.7 CDI85514.1 - 2.5 6.9 9.9 2.7 6.8 6.9 1.2 1 0 0 1 1 1 0 YabG peptidase U57 PPP4R2 PF09184.6 CDI85514.1 - 2.6 7.5 21.9 3.2 7.2 15.1 1.1 1 0 0 1 1 1 0 PPP4R2 Suc_Fer-like PF06999.7 CDI85514.1 - 2.6 7.9 11.7 3.4 7.6 8.1 1.1 1 0 0 1 1 1 0 Sucrase/ferredoxin-like FHIPEP PF00771.15 CDI85514.1 - 2.7 6.2 7.4 3.2 5.9 5.1 1.2 1 0 0 1 1 1 0 FHIPEP family DUF605 PF04652.11 CDI85514.1 - 2.9 7.1 29.3 3.3 7.0 20.3 1.0 1 0 0 1 1 1 0 Vta1 like Asp-B-Hydro_N PF05279.6 CDI85514.1 - 3.1 7.5 12.6 3.6 7.3 8.7 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region DUF3043 PF11241.3 CDI85514.1 - 3.2 7.3 8.1 3.8 7.0 5.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) RR_TM4-6 PF06459.7 CDI85514.1 - 3.2 7.5 18.7 4 7.2 13.0 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 AAA_23 PF13476.1 CDI85514.1 - 3.4 7.9 16.6 4.3 7.6 11.5 1.1 1 0 0 1 1 1 0 AAA domain DOR PF14839.1 CDI85514.1 - 3.6 7.2 26.0 5 6.8 18.0 1.2 1 0 0 1 1 1 0 DOR family CDC45 PF02724.9 CDI85514.1 - 3.8 5.4 24.4 4.5 5.1 16.9 1.0 1 0 0 1 1 1 0 CDC45-like protein IncA PF04156.9 CDI85514.1 - 3.8 7.0 19.8 4.8 6.7 13.8 1.3 1 0 0 1 1 1 0 IncA protein Borrelia_P83 PF05262.6 CDI85514.1 - 4.5 5.4 15.3 4.7 5.3 10.6 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Herpes_UL87 PF03043.9 CDI85514.1 - 4.5 5.5 11.6 4.7 5.4 8.0 1.0 1 0 0 1 1 1 0 Herpesvirus UL87 family BTV_NS2 PF04514.7 CDI85514.1 - 5 5.9 15.5 6.7 5.4 10.8 1.2 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 TFIIA PF03153.8 CDI85514.1 - 5.8 6.7 31.6 6.7 6.5 21.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4407 PF14362.1 CDI85514.1 - 6 5.7 15.3 6.3 5.6 10.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Ycf1 PF05758.7 CDI85514.1 - 6.1 4.4 15.4 6 4.4 10.7 1.1 1 0 0 1 1 1 0 Ycf1 Lipoprotein_10 PF03202.8 CDI85514.1 - 6.1 6.8 17.8 7.3 6.6 12.3 1.2 1 0 0 1 1 1 0 Putative mycoplasma lipoprotein, C-terminal region Herpes_DNAp_acc PF04929.7 CDI85514.1 - 6.2 5.6 21.4 7.3 5.4 14.9 1.0 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Cellulose_synt PF03552.9 CDI85514.1 - 6.3 4.9 8.9 6.5 4.9 6.1 1.0 1 0 0 1 1 1 0 Cellulose synthase GAGA_bind PF06217.7 CDI85514.1 - 7.5 6.4 18.1 8.9 6.1 12.6 1.0 1 0 0 1 1 1 0 GAGA binding protein-like family MMR1 PF08505.5 CDI85514.1 - 7.6 6.5 29.3 9.8 6.1 20.3 1.2 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein Lipoprotein_2 PF00921.12 CDI85514.1 - 7.6 6.5 6.8 9.2 6.2 4.7 1.1 1 0 0 1 1 1 0 Borrelia lipoprotein PIH1 PF08190.7 CDI85514.1 - 7.9 5.8 23.1 8.6 5.6 16.0 1.1 1 0 0 1 1 1 0 pre-RNA processing PIH1/Nop17 Zip PF02535.17 CDI85514.1 - 9.2 5.1 17.0 12 4.8 11.8 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter DUF4603 PF15376.1 CDI85514.1 - 9.8 3.2 21.3 11 2.9 14.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) Symplekin_C PF12295.3 CDI85515.1 - 1.7e-23 83.5 0.0 2.9e-23 82.7 0.0 1.4 1 0 0 1 1 1 1 Symplekin tight junction protein C terminal Spt20 PF12090.3 CDI85515.1 - 0.078 12.3 4.4 4.2 6.6 1.3 2.3 2 0 0 2 2 2 0 Spt20 family RAB3GAP2_N PF14655.1 CDI85515.1 - 0.53 9.2 10.4 0.74 8.7 0.2 2.4 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus WD40 PF00400.27 CDI85516.1 - 7.3e-06 25.6 10.1 0.0091 15.8 0.0 4.3 4 0 0 4 4 4 3 WD domain, G-beta repeat SR-25 PF10500.4 CDI85516.1 - 0.00083 18.8 4.8 0.00083 18.8 3.3 3.4 4 0 0 4 4 4 1 Nuclear RNA-splicing-associated protein Ribosomal_60s PF00428.14 CDI85516.1 - 1.5 9.2 22.5 2.4 8.5 5.2 3.5 3 0 0 3 3 3 0 60s Acidic ribosomal protein DUF3357 PF11837.3 CDI85521.1 - 0.029 14.2 0.1 0.065 13.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) Exonuc_V_gamma PF04257.9 CDI85522.1 - 0.017 13.1 0.0 0.023 12.6 0.0 1.1 1 0 0 1 1 1 0 Exodeoxyribonuclease V, gamma subunit ACT_6 PF13740.1 CDI85524.1 - 0.16 11.7 0.0 0.42 10.3 0.0 1.6 1 0 0 1 1 1 0 ACT domain MAR_sialic_bdg PF10564.4 CDI85526.1 - 0.00028 20.6 7.7 0.0021 17.7 0.2 3.1 3 0 0 3 3 3 2 Sialic-acid binding micronemal adhesive repeat Utp14 PF04615.8 CDI85527.1 - 0.041 12.0 22.8 0.041 12.0 15.8 1.0 1 0 0 1 1 1 0 Utp14 protein NABP PF07990.7 CDI85527.1 - 0.047 12.9 13.5 0.05 12.8 9.4 1.1 1 0 0 1 1 1 0 Nucleic acid binding protein NABP Spore_coat_CotO PF14153.1 CDI85527.1 - 0.29 10.5 27.1 0.35 10.2 18.8 1.2 1 0 0 1 1 1 0 Spore coat protein CotO PLRV_ORF5 PF01690.12 CDI85527.1 - 0.37 9.8 18.5 0.36 9.9 12.8 1.0 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein FemAB PF02388.11 CDI85527.1 - 0.42 9.2 14.7 0.49 9.0 10.2 1.1 1 0 0 1 1 1 0 FemAB family Daxx PF03344.10 CDI85527.1 - 0.48 8.8 19.3 0.46 8.9 13.4 1.1 1 0 0 1 1 1 0 Daxx Family SAPS PF04499.10 CDI85527.1 - 0.96 8.0 15.8 0.87 8.1 10.9 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Plasmodium_Vir PF05795.6 CDI85527.1 - 1.2 8.2 9.4 1.6 7.8 6.5 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein SPX PF03105.14 CDI85527.1 - 1.6 8.4 16.4 1.6 8.4 11.4 1.1 1 0 0 1 1 1 0 SPX domain SAGA-Tad1 PF12767.2 CDI85527.1 - 1.8 8.2 20.1 2.1 7.9 13.9 1.2 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit DUF966 PF06136.8 CDI85527.1 - 2 7.7 17.3 2.3 7.5 12.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Phosphoesterase PF04185.9 CDI85527.1 - 2.3 7.2 12.1 2.5 7.2 8.4 1.1 1 0 0 1 1 1 0 Phosphoesterase family DUF4045 PF13254.1 CDI85527.1 - 2.6 7.2 24.0 3.2 6.9 16.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Herpes_env PF01673.13 CDI85527.1 - 4.9 5.5 12.8 5 5.5 8.9 1.1 1 0 0 1 1 1 0 Herpesvirus putative major envelope glycoprotein Otopetrin PF03189.8 CDI85527.1 - 5 5.9 5.6 5.2 5.9 3.9 1.2 1 0 0 1 1 1 0 Otopetrin Med15 PF09606.5 CDI85527.1 - 6.7 4.7 63.8 8.9 4.3 44.2 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Peptidase_S64 PF08192.6 CDI85527.1 - 7.3 4.7 16.3 7.2 4.8 11.3 1.1 1 0 0 1 1 1 0 Peptidase family S64 FUSC PF04632.7 CDI85527.1 - 8 4.7 24.8 9.6 4.4 17.2 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family PAT1 PF09770.4 CDI85527.1 - 8.2 4.5 51.6 9.4 4.3 35.8 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 CDC45 PF02724.9 CDI85527.1 - 9.4 4.1 22.6 10 3.9 15.6 1.1 1 0 0 1 1 1 0 CDC45-like protein Draxin PF15550.1 CDI85527.1 - 9.6 5.7 16.9 14 5.2 11.7 1.3 1 0 0 1 1 1 0 Draxin LMBR1 PF04791.11 CDI85527.1 - 9.9 4.6 5.8 8.4 4.8 4.0 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Serinc PF03348.10 CDI85528.1 - 0.084 11.5 2.3 0.1 11.2 1.6 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) Med15 PF09606.5 CDI85528.1 - 0.11 10.7 32.3 0.17 10.0 22.4 1.3 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal PAT1 PF09770.4 CDI85528.1 - 0.12 10.5 24.6 0.14 10.3 17.0 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Suf PF05843.9 CDI85528.1 - 0.22 11.2 11.4 0.27 10.9 7.9 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) FimP PF09766.4 CDI85528.1 - 0.41 9.6 12.8 0.72 8.8 8.9 1.3 1 0 0 1 1 1 0 Fms-interacting protein DDHD PF02862.12 CDI85528.1 - 0.64 9.7 5.9 0.79 9.4 4.1 1.2 1 0 0 1 1 1 0 DDHD domain CDK5_activator PF03261.10 CDI85528.1 - 0.74 9.0 7.3 1.2 8.4 5.1 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein TFIIA PF03153.8 CDI85528.1 - 0.82 9.5 26.1 1 9.1 18.1 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RAB3GAP2_N PF14655.1 CDI85528.1 - 0.93 8.4 5.4 1.3 7.9 3.7 1.2 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Ndc1_Nup PF09531.5 CDI85528.1 - 2.4 6.4 4.7 2.8 6.2 3.2 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup RR_TM4-6 PF06459.7 CDI85528.1 - 2.7 7.8 12.4 3.5 7.4 8.6 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Presenilin PF01080.12 CDI85528.1 - 4.2 6.1 6.8 5.5 5.7 4.7 1.2 1 0 0 1 1 1 0 Presenilin DUF913 PF06025.7 CDI85528.1 - 8.9 4.9 7.0 12 4.5 4.8 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) MCM PF00493.18 CDI85529.1 - 0.023 13.5 2.0 0.039 12.7 1.4 1.3 1 0 0 1 1 1 0 MCM2/3/5 family SseC PF04888.7 CDI85530.1 - 4 6.6 74.2 6.2 6.0 51.4 1.3 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family TFIIA PF03153.8 CDI85530.1 - 7.1 6.4 26.1 8.6 6.1 18.1 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CAF-1_p150 PF11600.3 CDI85532.1 - 3.8e-05 23.1 31.7 5.2e-05 22.7 22.0 1.1 1 0 0 1 1 1 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal SOBP PF15279.1 CDI85532.1 - 0.23 11.7 28.8 0.27 11.5 20.0 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein PRP1_N PF06424.7 CDI85532.1 - 0.26 11.6 14.4 0.34 11.2 10.0 1.3 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal GAGA_bind PF06217.7 CDI85532.1 - 0.28 11.0 19.9 0.31 10.9 13.8 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family RR_TM4-6 PF06459.7 CDI85532.1 - 0.32 10.8 21.1 0.44 10.3 14.6 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 AAA_23 PF13476.1 CDI85532.1 - 0.4 10.9 22.9 0.57 10.4 15.8 1.2 1 0 0 1 1 1 0 AAA domain Utp14 PF04615.8 CDI85532.1 - 1.1 7.2 28.6 1.3 7.1 19.8 1.1 1 0 0 1 1 1 0 Utp14 protein PAT1 PF09770.4 CDI85532.1 - 1.7 6.7 55.1 2.2 6.4 38.2 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 APG6 PF04111.7 CDI85532.1 - 5.3 5.9 26.8 6.4 5.7 18.6 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Parvo_coat PF00740.13 CDI85532.1 - 6.9 5.4 26.9 7.8 5.3 18.6 1.1 1 0 0 1 1 1 0 Parvovirus coat protein VP2 FixO PF02433.10 CDI85532.1 - 7 5.9 13.1 11 5.2 9.1 1.3 1 0 0 1 1 1 0 Cytochrome C oxidase, mono-heme subunit/FixO SprA-related PF12118.3 CDI85533.1 - 0.05 12.9 72.9 0.0077 15.5 23.0 2.2 2 0 0 2 2 2 0 SprA-related family DUF4367 PF14285.1 CDI85533.1 - 0.38 10.0 4.8 2.2 7.5 0.0 2.9 3 1 0 3 3 3 0 Domain of unknown function (DUF4367) SR-25 PF10500.4 CDI85534.1 - 0.00032 20.2 3.3 0.00032 20.2 2.3 8.4 5 2 3 8 8 8 3 Nuclear RNA-splicing-associated protein BAF1_ABF1 PF04684.8 CDI85534.1 - 0.0006 18.7 15.8 0.0006 18.7 11.0 15.7 5 4 6 12 12 12 1 BAF1 / ABF1 chromatin reorganising factor CDK2AP PF09806.4 CDI85535.1 - 0.018 15.3 4.4 0.018 15.3 3.0 6.8 1 1 4 5 5 5 0 Cyclin-dependent kinase 2-associated protein PROCT PF08084.6 CDI85535.1 - 0.033 13.9 0.1 0.066 12.9 0.1 1.4 1 0 0 1 1 1 0 PROCT (NUC072) domain PSCyt3 PF07627.6 CDI85538.1 - 0.023 14.5 1.0 0.023 14.5 0.7 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1588) Neur_chan_memb PF02932.11 CDI85538.1 - 0.18 11.6 10.5 1.3 8.8 3.0 2.2 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region SASRP1 PF15160.1 CDI85538.1 - 0.61 9.2 5.6 1.2 8.2 3.9 1.5 1 0 0 1 1 1 0 Spermatogenesis-associated serine-rich protein 1 SR-25 PF10500.4 CDI85538.1 - 0.62 9.4 44.3 1.8 7.9 1.2 3.4 3 0 0 3 3 3 0 Nuclear RNA-splicing-associated protein Activator_LAG-3 PF11498.3 CDI85538.1 - 1.2 7.8 37.9 0.051 12.3 20.4 2.3 2 0 0 2 2 2 0 Transcriptional activator LAG-3 Apt1 PF10351.4 CDI85538.1 - 6.4 5.5 18.2 1.5 7.6 6.0 2.1 2 0 0 2 2 2 0 Golgi-body localisation protein domain SprA-related PF12118.3 CDI85539.1 - 0.004 16.5 43.0 0.004 16.5 29.8 2.2 2 0 0 2 2 2 1 SprA-related family DUF1510 PF07423.6 CDI85539.1 - 0.57 9.5 38.1 1.4 8.2 11.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) FLO_LFY PF01698.11 CDI85539.1 - 7.1 5.3 38.1 2.5 6.8 9.1 2.1 2 0 0 2 2 2 0 Floricaula / Leafy protein SR-25 PF10500.4 CDI85540.1 - 1.5e-11 44.2 51.8 7.3e-06 25.6 12.2 3.3 3 0 0 3 3 3 2 Nuclear RNA-splicing-associated protein DUF3633 PF12315.3 CDI85540.1 - 1.6e-05 24.3 40.9 2.6e-05 23.6 14.7 4.4 2 2 1 3 3 3 2 Protein of unknown function (DUF3633) GAGA_bind PF06217.7 CDI85540.1 - 0.0017 18.3 39.4 0.076 12.9 8.5 3.2 3 0 0 3 3 3 2 GAGA binding protein-like family DUF3464 PF11947.3 CDI85540.1 - 0.0033 16.8 10.2 0.0033 16.8 7.1 4.3 4 1 1 5 5 4 1 Protein of unknown function (DUF3464) PAT1 PF09770.4 CDI85540.1 - 0.031 12.5 99.6 0.26 9.4 25.3 3.1 3 0 0 3 3 3 0 Topoisomerase II-associated protein PAT1 DUF1510 PF07423.6 CDI85540.1 - 0.11 11.7 50.2 0.3 10.4 11.2 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1510) DDHD PF02862.12 CDI85540.1 - 0.21 11.3 49.3 0.76 9.5 11.4 3.3 3 0 0 3 3 3 0 DDHD domain Vfa1 PF08432.5 CDI85540.1 - 0.23 11.4 45.9 0.17 11.8 9.5 3.4 3 0 0 3 3 3 0 AAA-ATPase Vps4-associated protein 1 Suf PF05843.9 CDI85540.1 - 0.31 10.7 59.8 0.96 9.1 13.5 3.4 3 0 0 3 3 3 0 Suppressor of forked protein (Suf) AUX_IAA PF02309.11 CDI85540.1 - 1.4 8.6 39.2 1.2 8.7 7.9 3.3 3 0 0 3 3 3 0 AUX/IAA family RR_TM4-6 PF06459.7 CDI85540.1 - 1.5 8.6 49.9 3.1 7.6 12.8 3.3 3 0 0 3 3 3 0 Ryanodine Receptor TM 4-6 Hid1 PF12722.2 CDI85540.1 - 3.5 5.2 49.3 1.3 6.6 12.9 3.0 3 0 0 3 3 3 0 High-temperature-induced dauer-formation protein Parvo_coat PF00740.13 CDI85540.1 - 3.9 6.3 46.7 0.73 8.7 10.5 3.0 3 0 0 3 3 3 0 Parvovirus coat protein VP2 FAM60A PF15396.1 CDI85540.1 - 4 7.1 47.4 2.2 7.9 8.7 3.3 3 0 0 3 3 3 0 Protein Family FAM60A CAF-1_p150 PF11600.3 CDI85540.1 - 4.8 6.4 67.9 0.32 10.3 15.9 3.2 3 0 0 3 3 3 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal NMDAR2_C PF10565.4 CDI85541.1 - 0.099 11.3 6.3 0.14 10.7 4.4 1.2 1 0 0 1 1 1 0 N-methyl D-aspartate receptor 2B3 C-terminus TFIIA PF03153.8 CDI85541.1 - 3.3 7.5 37.0 4.3 7.1 25.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Macoilin PF09726.4 CDI85541.1 - 5 5.2 11.0 6 5.0 7.7 1.1 1 0 0 1 1 1 0 Transmembrane protein DUF1467 PF07330.7 CDI85542.1 - 0.021 14.5 1.3 1.9 8.3 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1467) Med15 PF09606.5 CDI85542.1 - 7.9 4.5 113.6 0.39 8.8 74.6 1.6 1 1 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal TRAP_alpha PF03896.11 CDI85543.1 - 0.1 11.5 6.2 0.12 11.3 4.3 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Herpes_MCP PF03122.9 CDI85543.1 - 0.11 9.8 16.4 0.12 9.7 11.4 1.0 1 0 0 1 1 1 0 Herpes virus major capsid protein Zip PF02535.17 CDI85543.1 - 0.17 10.8 8.4 0.19 10.7 5.8 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Rtf2 PF04641.7 CDI85543.1 - 0.18 10.9 23.2 0.2 10.8 16.0 1.0 1 0 0 1 1 1 0 Rtf2 RING-finger DUF1510 PF07423.6 CDI85543.1 - 0.19 11.0 27.8 0.22 10.8 19.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) NPR3 PF03666.8 CDI85543.1 - 0.3 9.5 23.9 0.35 9.3 16.6 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 SpoIIP PF07454.6 CDI85543.1 - 0.49 9.5 21.8 0.71 8.9 15.1 1.3 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Herpes_env PF01673.13 CDI85543.1 - 0.94 7.9 19.5 0.93 7.9 13.5 1.0 1 0 0 1 1 1 0 Herpesvirus putative major envelope glycoprotein Raftlin PF15250.1 CDI85543.1 - 1.8 6.9 23.8 2.1 6.7 16.5 1.0 1 0 0 1 1 1 0 Raftlin FAM60A PF15396.1 CDI85543.1 - 2.3 7.9 22.5 2.7 7.7 15.6 1.0 1 0 0 1 1 1 0 Protein Family FAM60A DUF2052 PF09747.4 CDI85543.1 - 2.5 8.0 32.6 3 7.7 22.6 1.1 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) DUF3807 PF12720.2 CDI85543.1 - 2.6 8.1 34.4 3.3 7.8 23.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) DUF3260 PF11658.3 CDI85543.1 - 2.6 6.0 25.3 2.8 5.9 17.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3260) AUX_IAA PF02309.11 CDI85543.1 - 2.8 7.6 21.9 3.3 7.3 15.2 1.1 1 0 0 1 1 1 0 AUX/IAA family RP-C_C PF11800.3 CDI85543.1 - 3 7.5 21.4 3.7 7.2 14.8 1.2 1 0 0 1 1 1 0 Replication protein C C-terminal region SAPS PF04499.10 CDI85543.1 - 3.1 6.3 24.3 3.4 6.1 16.8 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein HCO3_cotransp PF00955.16 CDI85543.1 - 3.3 6.2 11.7 3.6 6.1 8.1 1.0 1 0 0 1 1 1 0 HCO3- transporter family Ycf1 PF05758.7 CDI85543.1 - 3.7 5.1 30.0 3.9 5.0 20.8 1.0 1 0 0 1 1 1 0 Ycf1 Vfa1 PF08432.5 CDI85543.1 - 5.2 7.0 28.0 6.1 6.8 19.4 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 VID27 PF08553.5 CDI85543.1 - 5.6 5.0 20.1 5.9 4.9 13.9 1.0 1 0 0 1 1 1 0 VID27 cytoplasmic protein CDC45 PF02724.9 CDI85543.1 - 6.6 4.6 25.8 7.9 4.3 17.9 1.0 1 0 0 1 1 1 0 CDC45-like protein Hom_end_hint PF05203.11 CDI85543.1 - 6.8 6.3 18.5 8.9 5.9 12.8 1.1 1 0 0 1 1 1 0 Hom_end-associated Hint Plasmodium_Vir PF05795.6 CDI85543.1 - 7 5.7 11.3 9.5 5.3 7.8 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein DUF913 PF06025.7 CDI85543.1 - 7.3 5.2 16.0 9.9 4.7 11.1 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Senescence_reg PF04520.8 CDI85543.1 - 8.7 6.8 15.3 12 6.3 10.6 1.2 1 0 0 1 1 1 0 Senescence regulator FLO_LFY PF01698.11 CDI85543.1 - 9 5.0 24.5 12 4.6 17.0 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein DUF966 PF06136.8 CDI85543.1 - 9.5 5.5 24.3 12 5.1 16.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Tim54 PF11711.3 CDI85543.1 - 9.6 4.6 18.6 13 4.2 12.9 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Neur_chan_memb PF02932.11 CDI85543.1 - 9.6 6.0 21.1 12 5.7 14.7 1.0 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF912 PF06024.7 CDI85544.1 - 0.28 11.2 0.2 0.28 11.2 0.1 3.2 1 1 2 3 3 3 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF3328 PF11807.3 CDI85544.1 - 0.28 10.8 7.0 0.042 13.5 0.7 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3328) MethyltransfD12 PF02086.10 CDI85544.1 - 0.78 9.1 4.4 2.8 7.3 0.9 2.0 1 1 1 2 2 2 0 D12 class N6 adenine-specific DNA methyltransferase DUF3357 PF11837.3 CDI85544.1 - 0.83 9.5 16.4 0.71 9.7 6.2 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF3357) DUF3899 PF13038.1 CDI85544.1 - 1.4 9.1 0.0 1.4 9.1 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF3899) Herpes_env PF01673.13 CDI85544.1 - 1.7 7.1 14.9 2.2 6.7 10.3 1.2 1 0 0 1 1 1 0 Herpesvirus putative major envelope glycoprotein TFIIA PF03153.8 CDI85544.1 - 7.7 6.3 47.5 10 5.9 32.9 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit UPF0054 PF02130.12 CDI85545.1 - 1.5e-08 34.0 0.0 1.5e-08 34.0 0.0 2.8 2 1 0 2 2 1 1 Uncharacterized protein family UPF0054 IncA PF04156.9 CDI85545.1 - 6.1e-07 29.2 21.0 1.5e-05 24.6 9.8 2.3 2 0 0 2 2 2 2 IncA protein ACPS PF01648.15 CDI85545.1 - 3.6e-06 26.7 8.9 0.0027 17.5 7.3 3.1 2 1 0 2 2 2 1 4'-phosphopantetheinyl transferase superfamily TFIIA PF03153.8 CDI85545.1 - 0.0012 18.8 23.4 0.0016 18.3 16.2 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit PAT1 PF09770.4 CDI85545.1 - 0.0024 16.2 29.1 0.0028 15.9 20.2 1.1 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 Activator_LAG-3 PF11498.3 CDI85545.1 - 0.0054 15.5 42.1 0.0088 14.8 29.2 1.5 1 0 0 1 1 1 1 Transcriptional activator LAG-3 FLO_LFY PF01698.11 CDI85545.1 - 0.0091 14.8 7.6 0.012 14.5 5.3 1.2 1 0 0 1 1 1 1 Floricaula / Leafy protein Med15 PF09606.5 CDI85545.1 - 0.013 13.7 47.9 0.021 13.0 33.2 1.3 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal SLD3 PF08639.5 CDI85545.1 - 0.016 13.8 13.6 0.023 13.3 9.4 1.1 1 0 0 1 1 1 0 DNA replication regulator SLD3 DUF4175 PF13779.1 CDI85545.1 - 0.03 12.0 42.6 0.057 11.1 29.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) SOBP PF15279.1 CDI85545.1 - 0.033 14.5 9.9 0.046 14.1 6.9 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein Cellulose_synt PF03552.9 CDI85545.1 - 0.063 11.5 4.6 0.085 11.1 3.2 1.1 1 0 0 1 1 1 0 Cellulose synthase AUX_IAA PF02309.11 CDI85545.1 - 0.1 12.3 9.0 0.14 11.8 6.2 1.3 1 0 0 1 1 1 0 AUX/IAA family DUF4045 PF13254.1 CDI85545.1 - 0.11 11.7 13.8 0.16 11.2 9.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Neur_chan_memb PF02932.11 CDI85545.1 - 0.13 12.1 13.6 0.26 11.1 9.4 1.5 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF966 PF06136.8 CDI85545.1 - 0.16 11.3 12.8 0.29 10.5 8.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Peptidase_S15 PF02129.13 CDI85545.1 - 0.18 11.1 13.3 0.29 10.5 9.2 1.4 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Spore_YhcN_YlaJ PF09580.5 CDI85545.1 - 0.2 11.7 12.0 0.32 11.0 8.3 1.4 1 0 0 1 1 1 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) Peptidase_S64 PF08192.6 CDI85545.1 - 0.21 9.8 7.3 0.25 9.6 5.1 1.1 1 0 0 1 1 1 0 Peptidase family S64 OATP PF03137.15 CDI85545.1 - 0.22 9.5 13.9 0.35 8.8 0.0 2.3 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Tetraspannin PF00335.15 CDI85545.1 - 0.24 10.6 7.3 0.29 10.3 0.0 2.2 2 0 0 2 2 2 0 Tetraspanin family Band_3_cyto PF07565.8 CDI85545.1 - 0.24 10.8 15.5 0.38 10.2 10.7 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain eIF-3_zeta PF05091.7 CDI85545.1 - 0.27 9.8 17.9 0.34 9.4 12.4 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) FemAB PF02388.11 CDI85545.1 - 0.29 9.7 18.6 0.41 9.2 12.9 1.2 1 0 0 1 1 1 0 FemAB family MMR1 PF08505.5 CDI85545.1 - 0.33 10.9 16.7 0.47 10.4 11.6 1.3 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein FAM60A PF15396.1 CDI85545.1 - 0.45 10.2 9.6 0.66 9.6 6.7 1.3 1 0 0 1 1 1 0 Protein Family FAM60A Presenilin PF01080.12 CDI85545.1 - 0.47 9.2 9.6 0.5 9.1 5.3 1.9 2 0 0 2 2 2 0 Presenilin DUF775 PF05603.7 CDI85545.1 - 0.49 9.8 18.6 0.064 12.7 10.1 1.6 2 0 0 2 2 1 0 Protein of unknown function (DUF775) Paf1 PF03985.8 CDI85545.1 - 0.59 8.8 20.0 0.81 8.3 13.9 1.1 1 0 0 1 1 1 0 Paf1 Spore_coat_CotO PF14153.1 CDI85545.1 - 0.6 9.5 25.2 1 8.7 17.4 1.4 1 0 0 1 1 1 0 Spore coat protein CotO Mem_trans PF03547.13 CDI85545.1 - 0.73 8.0 2.4 1.1 7.4 1.6 1.3 1 0 0 1 1 1 0 Membrane transport protein DDHD PF02862.12 CDI85545.1 - 0.85 9.3 13.1 1.2 8.8 9.0 1.2 1 0 0 1 1 1 0 DDHD domain Serinc PF03348.10 CDI85545.1 - 0.96 8.0 10.5 1.7 7.2 7.3 1.5 1 0 0 1 1 1 0 Serine incorporator (Serinc) Macoilin PF09726.4 CDI85545.1 - 1.2 7.3 17.9 1.5 6.9 12.4 1.2 1 0 0 1 1 1 0 Transmembrane protein Suf PF05843.9 CDI85545.1 - 1.2 8.7 20.0 2 8.0 13.8 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Pyr_redox_2 PF07992.9 CDI85545.1 - 1.3 8.8 3.4 2.4 7.9 2.4 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase CDC45 PF02724.9 CDI85545.1 - 1.5 6.7 15.6 2.1 6.2 10.8 1.1 1 0 0 1 1 1 0 CDC45-like protein Plasmodium_Vir PF05795.6 CDI85545.1 - 1.6 7.8 3.5 2 7.5 2.5 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein CDK5_activator PF03261.10 CDI85545.1 - 1.7 7.9 12.9 2.5 7.3 8.9 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein SET PF00856.23 CDI85545.1 - 1.7 8.8 5.1 3 8.1 3.5 1.3 1 0 0 1 1 1 0 SET domain Gti1_Pac2 PF09729.4 CDI85545.1 - 2.1 8.2 8.8 4.3 7.1 6.1 1.6 1 0 0 1 1 1 0 Gti1/Pac2 family PIH1 PF08190.7 CDI85545.1 - 2.1 7.6 19.7 3.2 7.1 13.7 1.2 1 0 0 1 1 1 0 pre-RNA processing PIH1/Nop17 Asp-B-Hydro_N PF05279.6 CDI85545.1 - 2.3 7.9 16.0 3.8 7.3 11.1 1.3 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region RR_TM4-6 PF06459.7 CDI85545.1 - 2.5 7.8 18.5 4 7.2 12.8 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF1510 PF07423.6 CDI85545.1 - 2.6 7.3 21.9 4.6 6.5 14.8 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) Paramyxo_ncap PF00973.14 CDI85545.1 - 2.7 6.5 11.9 3.4 6.2 8.2 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein DUF4220 PF13968.1 CDI85545.1 - 3.1 6.7 7.3 5.7 5.9 5.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4220) Pex14_N PF04695.8 CDI85545.1 - 3.5 7.6 23.9 0.34 10.9 13.2 1.8 2 0 0 2 2 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF2146 PF10220.4 CDI85545.1 - 3.6 5.4 17.8 5 4.9 12.3 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2146) DDRGK PF09756.4 CDI85545.1 - 3.8 6.8 27.1 6.8 6.0 18.8 1.4 1 0 0 1 1 1 0 DDRGK domain BTV_NS2 PF04514.7 CDI85545.1 - 4.3 6.1 14.9 6.2 5.5 10.3 1.2 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Mgr1 PF08602.5 CDI85545.1 - 4.6 6.1 9.2 6.4 5.6 6.4 1.1 1 0 0 1 1 1 0 Mgr1-like, i-AAA protease complex subunit Ycf1 PF05758.7 CDI85545.1 - 4.8 4.7 19.6 0.097 10.3 9.1 1.4 2 0 0 2 2 2 0 Ycf1 HD-ZIP_N PF04618.7 CDI85545.1 - 5.1 7.6 11.4 11 6.5 7.9 1.6 1 0 0 1 1 1 0 HD-ZIP protein N terminus Sporozoite_P67 PF05642.6 CDI85545.1 - 5.6 4.6 13.2 11 3.6 0.0 2.0 2 0 0 2 2 2 0 Sporozoite P67 surface antigen DUF913 PF06025.7 CDI85545.1 - 5.7 5.5 9.6 8.4 5.0 6.6 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DHHW PF14286.1 CDI85545.1 - 5.9 6.0 15.3 8 5.6 10.6 1.1 1 0 0 1 1 1 0 DHHW protein DUF4638 PF15472.1 CDI85545.1 - 9.8 5.6 15.3 14 5.1 10.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) WD40 PF00400.27 CDI85547.1 - 3.2e-11 42.6 10.5 3.6e-06 26.6 0.4 5.8 5 1 0 5 5 5 3 WD domain, G-beta repeat Ribosomal_60s PF00428.14 CDI85547.1 - 0.21 11.9 21.4 0.058 13.7 2.8 3.6 3 0 0 3 3 3 0 60s Acidic ribosomal protein Senescence_reg PF04520.8 CDI85548.1 - 0.2 12.1 3.1 0.23 11.9 2.2 1.2 1 0 0 1 1 1 0 Senescence regulator DUF3379 PF11859.3 CDI85548.1 - 0.6 9.2 5.4 0.77 8.8 3.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3379) Med15 PF09606.5 CDI85548.1 - 2.7 6.0 10.3 3.2 5.8 7.1 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal RAB3GAP2_N PF14655.1 CDI85548.1 - 3.9 6.3 7.1 1.8 7.4 3.5 1.4 1 1 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Peroxidase_2 PF01328.12 CDI85548.1 - 4.9 5.7 8.5 6 5.4 5.9 1.1 1 0 0 1 1 1 0 Peroxidase, family 2 FCP1_C PF09309.5 CDI85549.1 - 7.2e-05 22.2 3.6 7.2e-05 22.2 2.5 2.3 2 0 0 2 2 2 1 FCP1, C-terminal Ribosomal_60s PF00428.14 CDI85549.1 - 0.0066 16.8 5.2 0.0066 16.8 3.6 5.9 5 2 0 5 5 3 1 60s Acidic ribosomal protein Collagen PF01391.13 CDI85549.1 - 0.0082 15.6 12.7 0.0082 15.6 8.8 1.9 2 0 0 2 2 2 1 Collagen triple helix repeat (20 copies) zf-DHHC PF01529.15 CDI85549.1 - 0.14 11.5 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 DHHC palmitoyltransferase AAA_23 PF13476.1 CDI85549.1 - 0.16 12.3 7.2 0.21 11.8 5.0 1.1 1 0 0 1 1 1 0 AAA domain FimP PF09766.4 CDI85549.1 - 0.22 10.5 17.0 0.31 10.0 11.8 1.1 1 0 0 1 1 1 0 Fms-interacting protein Spt20 PF12090.3 CDI85549.1 - 0.23 10.7 8.5 0.38 10.0 5.9 1.3 1 0 0 1 1 1 0 Spt20 family DUF4557 PF15101.1 CDI85549.1 - 0.28 11.0 17.0 0.55 10.0 11.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) Spore_coat_CotO PF14153.1 CDI85549.1 - 0.35 10.3 15.5 0.61 9.5 10.8 1.3 1 0 0 1 1 1 0 Spore coat protein CotO TFIIA PF03153.8 CDI85549.1 - 0.42 10.4 27.0 0.28 11.0 12.1 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Suf PF05843.9 CDI85549.1 - 0.54 9.9 12.5 0.89 9.2 8.7 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) PAT1 PF09770.4 CDI85549.1 - 0.9 7.6 28.9 1.5 7.0 20.0 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 RR_TM4-6 PF06459.7 CDI85549.1 - 1.3 8.8 13.1 0.079 12.8 5.4 1.6 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 DDHD PF02862.12 CDI85549.1 - 1.3 8.7 10.2 0.37 10.5 4.2 1.9 2 0 0 2 2 2 0 DDHD domain Neur_chan_memb PF02932.11 CDI85549.1 - 1.5 8.6 3.2 4.5 7.0 1.7 1.8 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region eIF-3_zeta PF05091.7 CDI85549.1 - 1.6 7.2 13.0 2.3 6.7 9.0 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF4526 PF15029.1 CDI85549.1 - 1.8 8.1 4.5 4.2 6.8 3.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4526) FLO_LFY PF01698.11 CDI85549.1 - 2.9 6.6 10.7 4.9 5.9 7.4 1.3 1 0 0 1 1 1 0 Floricaula / Leafy protein Dala_Dala_lig_N PF01820.16 CDI85549.1 - 4 7.7 7.1 3 8.1 3.3 1.8 2 0 0 2 2 2 0 D-ala D-ala ligase N-terminus Ribosomal_60s PF00428.14 CDI85550.1 - 0.041 14.2 40.0 0.52 10.7 8.8 3.4 3 0 0 3 3 3 0 60s Acidic ribosomal protein Rifin_STEVOR PF02009.11 CDI85550.1 - 0.17 11.4 2.8 0.26 10.8 1.9 1.2 1 0 0 1 1 1 0 Rifin/stevor family SH3_2 PF07653.12 CDI85551.1 - 0.0019 17.6 0.0 0.0041 16.5 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Nitroreductase PF00881.19 CDI85552.1 - 0.0016 18.2 0.5 0.0021 17.8 0.3 1.1 1 0 0 1 1 1 1 Nitroreductase family Lipase_chap PF03280.9 CDI85552.1 - 0.0065 16.0 7.8 0.0065 16.0 5.4 2.1 2 0 0 2 2 2 1 Proteobacterial lipase chaperone protein DUF2215 PF10225.4 CDI85552.1 - 0.011 15.1 3.8 0.018 14.5 2.7 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) FimP PF09766.4 CDI85552.1 - 0.012 14.7 3.0 0.012 14.7 2.1 2.1 2 0 0 2 2 2 0 Fms-interacting protein PAT1 PF09770.4 CDI85552.1 - 0.034 12.4 20.7 0.037 12.2 14.4 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 eIF-3_zeta PF05091.7 CDI85552.1 - 0.053 12.1 6.7 0.064 11.8 4.6 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) UCR_Fe-S_N PF10399.4 CDI85552.1 - 0.057 12.6 1.8 0.14 11.3 1.2 1.6 1 0 0 1 1 1 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal DUF3357 PF11837.3 CDI85552.1 - 0.063 13.1 2.5 3.9 7.3 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3357) DUF2029 PF09594.5 CDI85552.1 - 0.08 12.4 0.3 0.19 11.1 0.2 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2029) DUF4647 PF15504.1 CDI85552.1 - 0.086 11.6 9.0 0.1 11.4 6.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4647) Neur_chan_memb PF02932.11 CDI85552.1 - 0.091 12.6 4.8 0.12 12.2 3.3 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region SAPS PF04499.10 CDI85552.1 - 0.098 11.2 3.2 0.12 11.0 2.2 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Med15 PF09606.5 CDI85552.1 - 0.15 10.2 29.1 0.18 9.9 20.2 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF2948 PF11164.3 CDI85552.1 - 0.16 11.6 2.6 1.6 8.3 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2948) Macoilin PF09726.4 CDI85552.1 - 0.19 9.9 7.1 0.23 9.7 4.9 1.0 1 0 0 1 1 1 0 Transmembrane protein DUF719 PF05334.8 CDI85552.1 - 0.26 11.3 5.6 0.044 13.8 0.8 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF719) DUF4175 PF13779.1 CDI85552.1 - 0.63 7.6 21.6 0.79 7.3 14.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) TFIIA PF03153.8 CDI85552.1 - 0.91 9.3 15.8 1.2 8.9 11.0 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit APC_CDC26 PF10471.4 CDI85552.1 - 1 10.1 22.7 0.93 10.2 4.5 2.4 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit 1 DUF4551 PF15087.1 CDI85552.1 - 1.1 7.5 11.6 1.5 7.0 7.9 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF4551) DUF4557 PF15101.1 CDI85552.1 - 1.1 8.9 14.4 3.4 7.4 1.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4557) Ipi1_N PF12333.3 CDI85552.1 - 1.2 9.0 10.9 2.9 7.9 2.4 3.4 2 2 2 4 4 4 0 Rix1 complex component involved in 60S ribosome maturation dsDNA_bind PF01984.15 CDI85552.1 - 1.6 8.7 20.1 3.6 7.6 6.7 2.4 2 0 0 2 2 2 0 Double-stranded DNA-binding domain Herpes_US9 PF06072.6 CDI85552.1 - 3.2 7.6 9.1 5.3 6.9 0.1 3.2 2 1 1 3 3 3 0 Alphaherpesvirus tegument protein US9 BRF1 PF07741.8 CDI85552.1 - 3.6 7.8 11.4 1.9 8.7 1.0 2.2 2 0 0 2 2 2 0 Brf1-like TBP-binding domain Hid1 PF12722.2 CDI85552.1 - 3.8 5.0 6.9 4.7 4.7 4.8 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein U3snoRNP10 PF12397.3 CDI85552.1 - 4 7.4 6.9 0.43 10.5 1.3 1.9 2 1 0 2 2 2 0 U3 small nucleolar RNA-associated protein 10 Ndc1_Nup PF09531.5 CDI85552.1 - 5.1 5.3 8.9 6.1 5.1 6.2 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup RskA PF10099.4 CDI85553.1 - 0.022 14.4 6.1 0.025 14.3 4.2 1.0 1 0 0 1 1 1 0 Anti-sigma-K factor rskA TALPID3 PF15324.1 CDI85553.1 - 0.037 11.3 10.3 0.04 11.2 7.2 1.0 1 0 0 1 1 1 0 Hedgehog signalling target Claudin_2 PF13903.1 CDI85553.1 - 0.039 13.6 2.9 0.048 13.3 2.0 1.2 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction ERbeta_N PF12497.3 CDI85553.1 - 0.19 11.5 2.6 0.19 11.5 1.8 1.2 1 0 0 1 1 1 0 Estrogen receptor beta DUF3617 PF12276.3 CDI85553.1 - 0.73 9.2 11.6 0.86 9.0 8.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3617) DUF756 PF05506.7 CDI85553.1 - 0.94 9.9 4.4 1.2 9.7 3.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF756) Activator_LAG-3 PF11498.3 CDI85553.1 - 2.3 6.8 23.9 2 7.0 16.6 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Med15 PF09606.5 CDI85553.1 - 3.1 5.8 23.6 3.2 5.8 16.4 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal OmpH PF03938.9 CDI85554.1 - 0.0001 22.2 0.7 0.0001 22.2 0.5 9.4 4 4 0 4 4 4 1 Outer membrane protein (OmpH-like) DUF2232 PF09991.4 CDI85554.1 - 0.024 13.6 0.1 0.024 13.6 0.1 4.7 6 0 0 6 6 6 0 Predicted membrane protein (DUF2232) Activator_LAG-3 PF11498.3 CDI85555.1 - 0.005 15.6 27.1 0.005 15.6 18.8 2.3 2 0 0 2 2 2 2 Transcriptional activator LAG-3 PAT1 PF09770.4 CDI85555.1 - 5 5.2 33.4 7.3 4.6 23.1 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Vfa1 PF08432.5 CDI85555.1 - 5.4 6.9 11.2 1.3 8.9 2.8 2.3 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 Collagen PF01391.13 CDI85556.1 - 1.9 8.1 13.2 62 3.2 7.8 3.0 2 1 0 2 2 2 0 Collagen triple helix repeat (20 copies) MIP-T3 PF10243.4 CDI85556.1 - 7.8 4.8 21.9 8.2 4.7 15.2 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Cactin_mid PF10312.4 CDI85558.1 - 1.3e-21 76.7 5.0 4.2e-21 75.0 0.5 3.1 2 1 0 2 2 2 1 Conserved mid region of cactin HisKA PF00512.20 CDI85558.1 - 0.22 11.5 3.9 0.43 10.6 0.9 2.5 2 0 0 2 2 2 0 His Kinase A (phospho-acceptor) domain Phage_connect_1 PF05135.8 CDI85558.1 - 0.34 11.0 3.1 0.54 10.4 0.2 2.5 1 1 1 2 2 2 0 Phage gp6-like head-tail connector protein 3HCDH_N PF02737.13 CDI85558.1 - 1 8.9 4.8 0.33 10.6 0.2 2.4 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain S1 PF00575.18 CDI85561.1 - 4.6e-07 29.8 0.0 1.4 9.0 0.0 6.6 6 1 0 6 6 6 3 S1 RNA binding domain TAS2R PF05296.8 CDI85562.1 - 0.28 10.0 3.5 0.71 8.6 2.4 1.6 1 0 0 1 1 1 0 Mammalian taste receptor protein (TAS2R) YppF PF14178.1 CDI85563.1 - 0.052 13.0 0.1 0.078 12.5 0.0 1.2 1 0 0 1 1 1 0 YppF-like protein DUF605 PF04652.11 CDI85564.1 - 0.0026 17.2 3.7 0.0027 17.1 2.5 1.1 1 0 0 1 1 1 1 Vta1 like IncA PF04156.9 CDI85565.1 - 2.8e-06 27.0 17.5 3.5e-06 26.7 12.1 1.1 1 0 0 1 1 1 1 IncA protein TraT PF05818.7 CDI85565.1 - 0.00097 18.6 11.1 0.0012 18.3 7.7 1.0 1 0 0 1 1 1 1 Enterobacterial TraT complement resistance protein Activator_LAG-3 PF11498.3 CDI85565.1 - 0.0072 15.1 41.5 0.0077 15.0 28.8 1.1 1 0 0 1 1 1 1 Transcriptional activator LAG-3 DUF2232 PF09991.4 CDI85565.1 - 0.018 14.0 3.2 0.021 13.8 2.2 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) SPC22 PF04573.7 CDI85565.1 - 0.028 13.6 0.2 0.038 13.2 0.2 1.1 1 0 0 1 1 1 0 Signal peptidase subunit DUF726 PF05277.7 CDI85565.1 - 0.046 12.6 1.1 0.053 12.4 0.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF726) DUF4418 PF14387.1 CDI85565.1 - 0.058 13.1 2.4 0.068 12.9 1.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4418) DUF4557 PF15101.1 CDI85565.1 - 0.058 13.2 17.7 0.062 13.1 12.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) Ctr PF04145.10 CDI85565.1 - 0.059 13.4 5.9 0.068 13.2 4.1 1.2 1 0 0 1 1 1 0 Ctr copper transporter family FHIPEP PF00771.15 CDI85565.1 - 0.064 11.5 7.3 0.076 11.3 5.1 1.1 1 0 0 1 1 1 0 FHIPEP family Med15 PF09606.5 CDI85565.1 - 0.071 11.3 43.5 0.11 10.7 30.2 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal FimP PF09766.4 CDI85565.1 - 0.082 11.9 16.4 0.092 11.7 11.4 1.1 1 0 0 1 1 1 0 Fms-interacting protein DDHD PF02862.12 CDI85565.1 - 0.1 12.4 7.1 0.11 12.2 4.9 1.1 1 0 0 1 1 1 0 DDHD domain FPN1 PF06963.7 CDI85565.1 - 0.14 10.5 2.5 0.17 10.2 1.7 1.1 1 0 0 1 1 1 0 Ferroportin1 (FPN1) FAM176 PF14851.1 CDI85565.1 - 0.14 11.8 3.6 0.17 11.5 2.5 1.2 1 0 0 1 1 1 0 FAM176 family YbgS PF13985.1 CDI85565.1 - 0.15 11.9 12.0 0.19 11.6 8.3 1.2 1 0 0 1 1 1 0 YbgS-like protein APG6 PF04111.7 CDI85565.1 - 0.22 10.5 15.4 0.23 10.4 10.7 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 PAT1 PF09770.4 CDI85565.1 - 0.23 9.6 29.3 0.24 9.5 20.3 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF2215 PF10225.4 CDI85565.1 - 0.25 10.7 6.0 0.3 10.5 4.2 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) DUF4613 PF15390.1 CDI85565.1 - 0.27 9.3 9.2 0.3 9.1 6.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) Suf PF05843.9 CDI85565.1 - 0.3 10.7 13.1 0.34 10.6 9.1 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Herpes_glycop PF01528.11 CDI85565.1 - 0.41 9.2 4.1 0.47 9.0 2.8 1.1 1 0 0 1 1 1 0 Herpesvirus glycoprotein M Cellulose_synt PF03552.9 CDI85565.1 - 0.49 8.6 5.8 0.51 8.5 4.0 1.1 1 0 0 1 1 1 0 Cellulose synthase Rxt3 PF08642.5 CDI85565.1 - 0.59 10.3 3.7 0.75 10.0 2.6 1.2 1 0 0 1 1 1 0 Histone deacetylation protein Rxt3 KBP_C PF12309.3 CDI85565.1 - 0.61 9.0 15.7 0.64 8.9 10.9 1.0 1 0 0 1 1 1 0 KIF-1 binding protein C terminal FLO_LFY PF01698.11 CDI85565.1 - 0.66 8.7 11.0 0.73 8.6 7.6 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein V_ATPase_I PF01496.14 CDI85565.1 - 0.68 7.7 5.1 0.66 7.7 3.5 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family HemX PF04375.9 CDI85565.1 - 0.7 8.4 30.6 0.8 8.2 21.2 1.1 1 0 0 1 1 1 0 HemX PMSI1 PF15322.1 CDI85565.1 - 0.74 8.8 12.5 0.85 8.6 8.7 1.0 1 0 0 1 1 1 0 Protein missing in infertile sperm 1, putative ACCA PF03255.9 CDI85565.1 - 0.85 9.1 9.5 1.1 8.8 6.6 1.1 1 0 0 1 1 1 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit Serinc PF03348.10 CDI85565.1 - 0.91 8.1 9.3 0.95 8.0 6.5 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) Gag_spuma PF03276.9 CDI85565.1 - 1.1 7.5 21.1 1.2 7.4 14.6 1.1 1 0 0 1 1 1 0 Spumavirus gag protein RNA_pol_Rpb1_5 PF04998.12 CDI85565.1 - 1.1 8.4 4.9 1.3 8.2 3.4 1.0 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 AMP-binding PF00501.23 CDI85565.1 - 1.1 7.5 5.2 1.2 7.4 3.6 1.1 1 0 0 1 1 1 0 AMP-binding enzyme Peptidase_S15 PF02129.13 CDI85565.1 - 1.2 8.4 12.6 1.4 8.2 8.8 1.1 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Bud13 PF09736.4 CDI85565.1 - 1.3 9.2 13.5 1.5 9.0 9.3 1.2 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex Band_3_cyto PF07565.8 CDI85565.1 - 1.3 8.4 11.4 1.5 8.2 7.9 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Paramyxo_ncap PF00973.14 CDI85565.1 - 1.5 7.4 9.4 1.6 7.3 6.5 1.0 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein SDH_beta PF03315.10 CDI85565.1 - 1.5 8.8 4.8 2 8.4 3.3 1.2 1 0 0 1 1 1 0 Serine dehydratase beta chain AAA_23 PF13476.1 CDI85565.1 - 1.6 8.9 16.6 1.9 8.7 11.5 1.1 1 0 0 1 1 1 0 AAA domain CD20 PF04103.10 CDI85565.1 - 2 8.3 5.8 3.1 7.7 4.0 1.5 1 1 0 1 1 1 0 CD20-like family Bac_luciferase PF00296.15 CDI85565.1 - 2.1 7.4 12.2 2.3 7.2 8.4 1.0 1 0 0 1 1 1 0 Luciferase-like monooxygenase Peptidase_U57 PF05582.7 CDI85565.1 - 2.1 7.2 8.7 2.4 7.0 6.0 1.1 1 0 0 1 1 1 0 YabG peptidase U57 Glt_symporter PF03616.9 CDI85565.1 - 2.1 6.7 5.5 3 6.2 3.8 1.2 1 0 0 1 1 1 0 Sodium/glutamate symporter Neur_chan_memb PF02932.11 CDI85565.1 - 2.3 8.0 5.4 2.5 7.9 3.8 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region MARCKS PF02063.12 CDI85565.1 - 2.4 7.9 21.9 2.9 7.6 15.2 1.1 1 0 0 1 1 1 0 MARCKS family HAUS6_N PF14661.1 CDI85565.1 - 2.8 7.2 21.2 3.3 7.0 14.7 1.0 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus HlyD_2 PF12700.2 CDI85565.1 - 3 6.8 10.0 3 6.9 7.0 1.1 1 0 0 1 1 1 0 HlyD family secretion protein Presenilin PF01080.12 CDI85565.1 - 3.2 6.5 8.9 3.3 6.4 6.2 1.0 1 0 0 1 1 1 0 Presenilin DUF2149 PF09919.4 CDI85565.1 - 3.6 7.7 6.9 4.6 7.4 4.8 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2149) DUF4228 PF14009.1 CDI85565.1 - 3.6 7.6 11.7 4.1 7.4 8.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4228) Cyto_heme_lyase PF01265.12 CDI85565.1 - 3.9 6.9 13.7 4.7 6.7 9.5 1.1 1 0 0 1 1 1 0 Cytochrome c/c1 heme lyase TFIIA PF03153.8 CDI85565.1 - 4 7.2 28.5 4.7 7.0 19.8 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF342 PF03961.8 CDI85565.1 - 4.8 5.4 8.0 5.1 5.3 5.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Sec62 PF03839.11 CDI85565.1 - 5.3 6.3 6.7 6.1 6.1 4.6 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 Fimbrial_K88 PF02432.10 CDI85565.1 - 5.9 6.2 8.6 7.3 5.9 6.0 1.1 1 0 0 1 1 1 0 Fimbrial, major and minor subunit FliP PF00813.15 CDI85565.1 - 6 6.5 6.0 6.7 6.3 4.1 1.2 1 0 0 1 1 1 0 FliP family Herpes_TAF50 PF03326.8 CDI85565.1 - 6.4 5.6 23.5 7.5 5.3 16.3 1.0 1 0 0 1 1 1 0 Herpesvirus transcription activation factor (transactivator) DUF1980 PF09323.5 CDI85565.1 - 7.5 6.2 8.4 8.9 6.0 5.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) N6_N4_Mtase PF01555.13 CDI85566.1 - 4.9e-05 22.9 0.4 18 4.6 0.0 4.1 3 1 0 3 3 3 1 DNA methylase BAF1_ABF1 PF04684.8 CDI85566.1 - 0.0032 16.3 18.5 0.0032 16.3 12.8 8.3 4 2 2 7 7 7 2 BAF1 / ABF1 chromatin reorganising factor Utp14 PF04615.8 CDI85566.1 - 6.2 4.8 79.3 0.17 9.9 24.4 3.2 3 0 0 3 3 3 0 Utp14 protein GSH_synth_ATP PF03917.12 CDI85567.1 - 1.2e-46 158.9 0.0 1.2e-24 86.6 0.0 6.1 3 3 0 3 3 3 3 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.10 CDI85567.1 - 4.5e-10 39.5 16.6 1.3e-09 38.0 1.5 3.8 4 0 0 4 4 4 2 Eukaryotic glutathione synthase SR-25 PF10500.4 CDI85567.1 - 0.00039 19.9 3.1 0.00039 19.9 2.1 5.8 6 0 0 6 6 6 1 Nuclear RNA-splicing-associated protein BAF1_ABF1 PF04684.8 CDI85567.1 - 0.0015 17.4 9.3 0.0015 17.4 6.4 9.9 9 2 1 10 10 10 2 BAF1 / ABF1 chromatin reorganising factor Ribosomal_60s PF00428.14 CDI85567.1 - 0.032 14.6 89.7 0.54 10.6 6.5 7.0 7 0 0 7 7 7 0 60s Acidic ribosomal protein Cellulose_synt PF03552.9 CDI85567.1 - 0.15 10.2 2.4 0.37 9.0 1.7 1.6 1 0 0 1 1 1 0 Cellulose synthase DUF4557 PF15101.1 CDI85567.1 - 7.3 6.3 59.4 0.24 11.1 9.3 6.3 6 0 0 6 6 6 0 Domain of unknown function (DUF4557) Trypan_glycop_C PF10659.4 CDI85571.1 - 0.0068 16.6 7.6 0.0068 16.6 5.3 7.6 8 1 1 9 9 9 1 Trypanosome variant surface glycoprotein C-terminal domain TauE PF01925.14 CDI85572.1 - 0.00033 20.1 18.0 0.00047 19.6 12.5 1.3 1 0 0 1 1 1 1 Sulfite exporter TauE/SafE Tmemb_9 PF05434.6 CDI85572.1 - 0.00054 19.7 3.4 0.00098 18.8 2.4 1.5 1 0 0 1 1 1 1 TMEM9 V_ATPase_I PF01496.14 CDI85572.1 - 0.0016 16.4 3.6 0.0017 16.2 2.5 1.1 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family Pex24p PF06398.6 CDI85572.1 - 0.0019 17.0 2.0 0.0019 17.0 1.4 1.1 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin YfhO PF09586.5 CDI85572.1 - 0.0026 15.8 11.1 0.0032 15.5 7.7 1.1 1 0 0 1 1 1 1 Bacterial membrane protein YfhO Neur_chan_memb PF02932.11 CDI85572.1 - 0.0032 17.3 1.8 0.0038 17.1 1.3 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region RSN1_TM PF13967.1 CDI85572.1 - 0.0044 16.5 1.0 0.008 15.7 0.7 1.5 1 0 0 1 1 1 1 Late exocytosis, associated with Golgi transport VirB3 PF05101.8 CDI85572.1 - 0.031 14.2 4.4 0.031 14.2 3.0 2.1 2 1 0 2 2 2 0 Type IV secretory pathway, VirB3-like protein 7tm_1 PF00001.16 CDI85572.1 - 0.038 13.1 7.5 0.054 12.6 5.1 1.4 1 1 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) SID-1_RNA_chan PF13965.1 CDI85572.1 - 0.046 11.8 1.0 0.05 11.7 0.7 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DUF1510 PF07423.6 CDI85572.1 - 0.058 12.7 10.7 0.19 11.1 7.4 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1510) Neur PF00064.13 CDI85572.1 - 0.061 11.3 2.6 0.064 11.3 1.8 1.2 1 0 0 1 1 1 0 Neuraminidase TMEM51 PF15345.1 CDI85572.1 - 0.07 12.8 17.0 0.1 12.2 11.8 1.4 1 1 0 1 1 1 0 Transmembrane protein 51 Cytochrom_B_N PF00033.14 CDI85572.1 - 0.075 12.3 15.8 0.33 10.2 10.9 1.9 1 1 0 1 1 1 0 Cytochrome b(N-terminal)/b6/petB Tenui_PVC2 PF06656.6 CDI85572.1 - 0.13 10.0 1.4 0.14 9.9 1.0 1.0 1 0 0 1 1 1 0 Tenuivirus PVC2 protein DUF3573 PF12097.3 CDI85572.1 - 0.13 10.8 3.7 0.14 10.7 2.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) DUF3328 PF11807.3 CDI85572.1 - 0.14 11.8 0.8 0.24 11.0 0.3 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF3328) SKN1 PF03935.10 CDI85572.1 - 0.14 10.2 1.9 0.16 10.1 1.3 1.2 1 0 0 1 1 1 0 Beta-glucan synthesis-associated protein (SKN1) Sarcoglycan_2 PF05510.8 CDI85572.1 - 0.15 10.2 3.4 0.19 9.9 2.4 1.3 1 0 0 1 1 1 0 Sarcoglycan alpha/epsilon PRA1 PF03208.14 CDI85572.1 - 0.22 10.8 17.3 0.73 9.1 12.0 1.8 1 1 0 1 1 1 0 PRA1 family protein Shisa PF13908.1 CDI85572.1 - 0.25 11.4 9.9 0.15 12.2 5.6 1.5 1 1 1 2 2 2 0 Wnt and FGF inhibitory regulator EspB PF05802.6 CDI85572.1 - 0.38 9.6 31.1 0.48 9.3 21.5 1.1 1 0 0 1 1 1 0 Enterobacterial EspB protein IER PF05760.7 CDI85572.1 - 0.55 10.1 15.6 0.72 9.7 10.8 1.1 1 0 0 1 1 1 0 Immediate early response protein (IER) Ni_hydr_CYTB PF01292.15 CDI85572.1 - 0.69 9.2 17.9 3.1 7.1 12.4 2.0 1 1 0 1 1 1 0 Prokaryotic cytochrome b561 Endonuc_Holl PF10107.4 CDI85572.1 - 0.72 9.5 7.6 1.5 8.4 5.2 1.5 1 0 0 1 1 1 0 Endonuclease related to archaeal Holliday junction resolvase DivIC PF04977.10 CDI85572.1 - 0.75 9.3 15.9 1.8 8.1 11.0 1.6 1 0 0 1 1 1 0 Septum formation initiator Tmemb_185A PF10269.4 CDI85572.1 - 0.89 9.1 11.8 7.6 6.0 8.2 2.1 1 1 0 1 1 1 0 Transmembrane Fragile-X-F protein Herpes_LMP1 PF05297.6 CDI85572.1 - 1.2 7.9 5.3 1.4 7.8 3.7 1.1 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) RED_N PF07808.8 CDI85572.1 - 1.2 8.2 8.5 2.1 7.5 5.9 1.3 1 0 0 1 1 1 0 RED-like protein N-terminal region DUF3260 PF11658.3 CDI85572.1 - 1.4 7.0 19.4 0.054 11.6 9.1 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3260) DUF929 PF06053.6 CDI85572.1 - 1.8 7.5 7.7 3.1 6.8 4.9 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF929) FAM150 PF15129.1 CDI85572.1 - 1.9 8.3 5.4 3.3 7.5 3.7 1.4 1 0 0 1 1 1 0 FAM150 family HN PF00423.14 CDI85572.1 - 2.1 6.5 5.1 2.9 6.0 3.5 1.2 1 0 0 1 1 1 0 Haemagglutinin-neuraminidase PAT1 PF09770.4 CDI85572.1 - 3.1 5.9 20.8 3.5 5.7 14.4 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 UPF0542 PF15086.1 CDI85572.1 - 4.2 7.1 6.9 2.6 7.8 3.0 1.9 1 1 1 2 2 2 0 Uncharacterised protein family UPF0542 Stig1 PF04885.8 CDI85572.1 - 5.3 7.2 8.1 1.9 8.6 2.6 2.1 1 1 1 2 2 2 0 Stigma-specific protein, Stig1 WES_acyltransf PF03007.11 CDI85572.1 - 6.2 6.2 16.5 8 5.9 11.4 1.1 1 0 0 1 1 1 0 Wax ester synthase-like Acyl-CoA acyltransferase domain PIG-P PF08510.7 CDI85572.1 - 7.3 6.2 9.1 17 5.0 6.2 1.9 1 1 0 1 1 1 0 PIG-P MFS_Mycoplasma PF07672.8 CDI85572.1 - 8.5 5.4 8.7 12 4.9 6.0 1.5 1 1 0 1 1 1 0 Mycoplasma MFS transporter IncA PF04156.9 CDI85573.1 - 0.032 13.8 0.8 0.032 13.8 0.6 2.2 2 0 0 2 2 2 0 IncA protein ATG13 PF10033.4 CDI85573.1 - 0.047 13.1 0.1 0.07 12.5 0.1 1.2 1 0 0 1 1 1 0 Autophagy-related protein 13 DUF694 PF05107.7 CDI85573.1 - 0.24 10.5 5.6 1.8 7.6 0.3 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF694) DUF2722 PF10846.3 CDI85574.1 - 0.0042 16.1 12.2 0.01 14.9 0.8 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF2722) Spc24 PF08286.6 CDI85574.1 - 0.0055 16.3 7.4 0.024 14.3 0.0 2.1 2 0 0 2 2 2 1 Spc24 subunit of Ndc80 DUF4106 PF13388.1 CDI85574.1 - 0.0072 15.3 2.9 0.0072 15.3 2.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF4106) Apc15p PF05841.6 CDI85574.1 - 0.021 15.5 15.2 0.53 11.0 1.2 2.3 2 0 0 2 2 2 0 Apc15p protein Spt20 PF12090.3 CDI85574.1 - 0.024 13.9 12.9 0.18 11.1 0.1 2.2 2 0 0 2 2 2 0 Spt20 family FAM176 PF14851.1 CDI85574.1 - 0.031 13.9 3.0 3.2 7.4 0.2 2.1 2 0 0 2 2 2 0 FAM176 family COX6A PF02046.10 CDI85574.1 - 0.041 13.7 3.5 0.55 10.1 0.0 2.3 2 0 0 2 2 2 0 Cytochrome c oxidase subunit VIa SeqA PF03925.8 CDI85574.1 - 0.099 12.3 8.2 0.2 11.3 0.1 2.1 2 0 0 2 2 2 0 SeqA protein Activator_LAG-3 PF11498.3 CDI85574.1 - 0.13 11.0 45.5 0.59 8.8 13.9 2.1 2 0 0 2 2 2 0 Transcriptional activator LAG-3 Pex14_N PF04695.8 CDI85574.1 - 0.17 11.9 18.7 1.2 9.1 1.9 2.2 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF972 PF06156.8 CDI85574.1 - 0.2 11.9 7.8 0.4 11.0 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF972) APC_CDC26 PF10471.4 CDI85574.1 - 0.27 11.9 29.2 1 10.1 8.1 2.7 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit 1 Neur_chan_memb PF02932.11 CDI85574.1 - 0.38 10.5 4.4 0.59 9.9 3.0 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region AIF_C PF14721.1 CDI85574.1 - 0.42 10.8 9.7 0.66 10.2 0.2 2.2 2 0 0 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term DUF3371 PF11851.3 CDI85574.1 - 0.42 11.3 18.6 0.45 11.1 2.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3371) FimP PF09766.4 CDI85574.1 - 0.7 8.9 24.5 0.97 8.4 6.8 2.0 2 0 0 2 2 2 0 Fms-interacting protein CD20 PF04103.10 CDI85574.1 - 0.72 9.7 4.0 1.2 9.0 0.0 2.2 2 0 0 2 2 2 0 CD20-like family UPF0560 PF10577.4 CDI85574.1 - 1.6 6.8 23.5 0.3 9.2 3.4 2.1 2 0 0 2 2 2 0 Uncharacterised protein family UPF0560 DUF912 PF06024.7 CDI85574.1 - 2.4 8.2 9.2 1.9 8.6 1.4 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Peptidase_S49_N PF08496.5 CDI85574.1 - 3 7.6 9.3 5.8 6.6 0.2 2.1 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Draxin PF15550.1 CDI85574.1 - 3.1 7.3 11.1 10 5.6 0.2 2.1 2 0 0 2 2 2 0 Draxin DUF775 PF05603.7 CDI85574.1 - 3.5 7.0 16.0 2.3 7.6 1.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF775) BORG_CEP PF14957.1 CDI85574.1 - 5.5 7.9 9.0 19 6.1 1.8 2.3 2 0 0 2 2 2 0 Cdc42 effector Hist_deacetyl PF00850.14 CDI85574.1 - 5.7 6.1 7.8 13 4.9 0.1 2.1 2 0 0 2 2 2 0 Histone deacetylase domain eIF_4EBP PF05456.6 CDI85574.1 - 7 6.3 10.3 10 5.8 2.3 2.2 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) CDK5_activator PF03261.10 CDI85574.1 - 8.9 5.5 14.0 10 5.3 0.3 2.1 2 0 0 2 2 2 0 Cyclin-dependent kinase 5 activator protein TMEM51 PF15345.1 CDI85574.1 - 9.8 5.7 14.8 8.3 6.0 1.1 2.1 2 0 0 2 2 2 0 Transmembrane protein 51 DUF1510 PF07423.6 CDI85575.1 - 0.25 10.6 29.3 0.29 10.4 20.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) FLO_LFY PF01698.11 CDI85575.1 - 1.1 8.0 21.5 1.3 7.8 14.9 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein Vfa1 PF08432.5 CDI85575.1 - 1.7 8.6 25.8 2.1 8.3 17.9 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 RNase_H2-Ydr279 PF09468.5 CDI85575.1 - 2.1 7.4 13.5 2.4 7.2 9.4 1.0 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) DDHD PF02862.12 CDI85575.1 - 2.1 8.0 20.1 2.8 7.6 13.9 1.1 1 0 0 1 1 1 0 DDHD domain GAGA_bind PF06217.7 CDI85575.1 - 2.3 8.1 22.1 2.6 7.9 15.3 1.0 1 0 0 1 1 1 0 GAGA binding protein-like family CDC45 PF02724.9 CDI85575.1 - 2.9 5.7 25.9 3.4 5.5 17.9 1.0 1 0 0 1 1 1 0 CDC45-like protein KilA-N PF04383.8 CDI85575.1 - 3.1 7.4 9.9 12 5.6 6.9 1.8 1 1 0 1 1 1 0 KilA-N domain BTV_NS2 PF04514.7 CDI85575.1 - 3.6 6.3 21.8 4.1 6.1 15.1 1.0 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 FAM60A PF15396.1 CDI85575.1 - 5.6 6.6 18.3 6.7 6.3 12.7 1.1 1 0 0 1 1 1 0 Protein Family FAM60A DUF4045 PF13254.1 CDI85575.1 - 5.6 6.1 21.5 6.3 5.9 14.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) SAGA-Tad1 PF12767.2 CDI85575.1 - 7.2 6.1 25.9 9.8 5.7 17.9 1.2 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit PA26 PF04636.8 CDI85575.1 - 7.4 5.1 19.8 8.4 4.9 13.7 1.0 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) RR_TM4-6 PF06459.7 CDI85575.1 - 7.5 6.3 23.1 9.6 6.0 16.0 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 TFIIA PF03153.8 CDI85575.1 - 7.5 6.3 40.2 8.4 6.1 27.9 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Hid1 PF12722.2 CDI85575.1 - 7.8 4.0 27.0 8.6 3.8 18.7 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF3584 PF12128.3 CDI85575.1 - 7.9 3.6 40.9 8.7 3.5 28.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Asp-B-Hydro_N PF05279.6 CDI85575.1 - 8 6.2 26.0 9.8 5.9 18.0 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region YscJ_FliF_C PF08345.6 CDI85575.1 - 9.8 6.1 24.5 16 5.4 17.0 1.4 1 0 0 1 1 1 0 Flagellar M-ring protein C-terminal Band_3_cyto PF07565.8 CDI85575.1 - 9.9 5.5 21.0 13 5.2 14.6 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain BRF1 PF07741.8 CDI85576.1 - 0.0017 18.5 0.7 0.0022 18.1 0.5 1.4 1 0 0 1 1 1 1 Brf1-like TBP-binding domain CemA PF03040.9 CDI85576.1 - 0.045 13.3 8.8 0.058 13.0 6.1 1.1 1 0 0 1 1 1 0 CemA family Neur_chan_memb PF02932.11 CDI85576.1 - 0.14 12.0 3.5 0.18 11.6 2.4 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF1694 PF07997.6 CDI85576.1 - 0.15 12.0 10.2 0.2 11.5 7.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1694) FHIPEP PF00771.15 CDI85576.1 - 0.46 8.7 11.2 0.55 8.4 7.8 1.1 1 0 0 1 1 1 0 FHIPEP family HI0933_like PF03486.9 CDI85576.1 - 0.63 8.4 11.2 0.72 8.2 7.8 1.1 1 0 0 1 1 1 0 HI0933-like protein Glyco_hydro_65m PF03632.10 CDI85576.1 - 0.87 8.1 5.4 1.1 7.8 3.8 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 65 central catalytic domain HlyD_2 PF12700.2 CDI85576.1 - 3.9 6.5 12.8 4.6 6.3 8.8 1.2 1 0 0 1 1 1 0 HlyD family secretion protein APG9 PF04109.11 CDI85576.1 - 4.8 5.9 9.5 6.7 5.5 6.6 1.1 1 0 0 1 1 1 0 Autophagy protein Apg9 Exonuc_VII_L PF02601.10 CDI85576.1 - 8.5 5.4 13.9 8.5 5.4 9.6 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Peptidase_S15 PF02129.13 CDI85576.1 - 8.8 5.6 8.5 13 5.1 5.9 1.3 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Suf PF05843.9 CDI85579.1 - 0.009 15.7 4.1 0.012 15.3 2.9 1.2 1 0 0 1 1 1 1 Suppressor of forked protein (Suf) Tmemb_185A PF10269.4 CDI85579.1 - 0.048 13.2 0.7 0.06 12.9 0.5 1.3 1 0 0 1 1 1 0 Transmembrane Fragile-X-F protein Shisa PF13908.1 CDI85579.1 - 0.06 13.5 3.4 0.079 13.1 2.3 1.2 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Peptidase_S49_N PF08496.5 CDI85579.1 - 0.11 12.3 6.3 0.15 11.8 4.4 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF106 PF01956.11 CDI85579.1 - 0.25 10.8 6.1 0.35 10.3 4.2 1.2 1 0 0 1 1 1 0 Integral membrane protein DUF106 DUF2513 PF10711.4 CDI85579.1 - 0.33 11.0 3.7 0.57 10.2 2.6 1.4 1 0 0 1 1 1 0 Hypothetical protein (DUF2513) SID-1_RNA_chan PF13965.1 CDI85579.1 - 0.43 8.6 4.2 0.47 8.5 2.9 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Neur_chan_memb PF02932.11 CDI85579.1 - 0.45 10.3 5.2 0.67 9.8 3.6 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region EphA2_TM PF14575.1 CDI85579.1 - 0.46 10.9 9.8 0.37 11.1 0.3 2.3 1 1 1 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain DUF4446 PF14584.1 CDI85579.1 - 0.53 10.1 7.7 0.79 9.5 5.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) Neur PF00064.13 CDI85579.1 - 0.56 8.2 3.0 0.7 7.9 2.1 1.1 1 0 0 1 1 1 0 Neuraminidase CemA PF03040.9 CDI85579.1 - 0.9 9.0 9.7 1.2 8.6 6.8 1.1 1 0 0 1 1 1 0 CemA family Endonuc_Holl PF10107.4 CDI85579.1 - 1.7 8.3 9.6 2.4 7.8 6.7 1.3 1 0 0 1 1 1 0 Endonuclease related to archaeal Holliday junction resolvase Anoctamin PF04547.7 CDI85579.1 - 2 7.0 7.1 2.4 6.7 4.9 1.1 1 0 0 1 1 1 0 Calcium-activated chloride channel ODV-E18 PF10717.4 CDI85579.1 - 2.7 7.4 6.8 38 3.8 4.7 2.3 1 1 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 Phage_lambd_GpG PF06894.6 CDI85579.1 - 3.8 7.1 13.2 6.2 6.4 9.1 1.3 1 0 0 1 1 1 0 Bacteriophage lambda minor tail protein (GpG) AAA_23 PF13476.1 CDI85579.1 - 4.1 7.6 12.3 5.1 7.3 8.6 1.1 1 0 0 1 1 1 0 AAA domain Baculo_11_kDa PF06143.6 CDI85579.1 - 4.8 6.6 12.3 0.46 9.8 1.9 3.0 2 1 0 2 2 2 0 Baculovirus 11 kDa family Jiraiya PF15038.1 CDI85579.1 - 5.1 6.4 9.4 0.76 9.1 3.4 1.8 1 1 1 2 2 2 0 Jiraiya TraF PF13728.1 CDI85579.1 - 7.8 5.9 18.3 10 5.5 12.7 1.1 1 0 0 1 1 1 0 F plasmid transfer operon protein K_oxygenase PF13434.1 CDI85580.1 - 0.5 9.2 18.9 0.53 9.1 13.1 1.1 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Parvo_coat PF00740.13 CDI85580.1 - 3.8 6.3 28.1 4.4 6.1 19.5 1.0 1 0 0 1 1 1 0 Parvovirus coat protein VP2 FLO_LFY PF01698.11 CDI85580.1 - 4.4 6.0 24.2 5.1 5.8 16.8 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein BTV_NS2 PF04514.7 CDI85580.1 - 7.1 5.4 19.1 8.1 5.2 13.2 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 DHHW PF14286.1 CDI85580.1 - 7.5 5.7 16.9 11 5.2 11.7 1.2 1 0 0 1 1 1 0 DHHW protein FAM60A PF15396.1 CDI85580.1 - 7.8 6.1 19.6 12 5.5 13.6 1.3 1 0 0 1 1 1 0 Protein Family FAM60A AAA_2 PF07724.9 CDI85581.1 - 7.5e-39 133.3 0.1 6.4e-38 130.3 0.1 2.1 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) ClpB_D2-small PF10431.4 CDI85581.1 - 6.6e-16 57.9 0.1 1.8e-15 56.5 0.1 1.8 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.9 CDI85581.1 - 3.6e-09 36.4 0.1 1.3e-08 34.6 0.1 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA PF00004.24 CDI85581.1 - 1.6e-08 34.7 0.0 4.4e-08 33.3 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 CDI85581.1 - 1.4e-07 31.1 0.0 2.4e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 Sigma-54 interaction domain Zeta_toxin PF06414.7 CDI85581.1 - 7.3e-05 21.9 0.0 0.00017 20.7 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin AAA_16 PF13191.1 CDI85581.1 - 0.00033 20.6 0.0 0.0011 18.9 0.0 1.8 1 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 CDI85581.1 - 0.0017 18.5 0.1 0.042 13.9 0.0 2.8 2 1 0 2 2 2 1 AAA domain Torsin PF06309.6 CDI85581.1 - 0.0019 18.0 0.0 0.0064 16.3 0.0 1.8 2 0 0 2 2 2 1 Torsin AAA_17 PF13207.1 CDI85581.1 - 0.0025 18.6 0.0 0.0085 16.9 0.0 2.0 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.7 CDI85581.1 - 0.0026 16.8 0.0 0.0045 16.0 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_18 PF13238.1 CDI85581.1 - 0.0034 17.7 0.0 0.021 15.1 0.0 2.3 2 1 1 3 3 3 1 AAA domain AAA_14 PF13173.1 CDI85581.1 - 0.0034 17.2 0.0 0.0091 15.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain DNA_pol3_delta2 PF13177.1 CDI85581.1 - 0.0086 15.7 0.0 0.023 14.3 0.0 1.8 1 1 0 1 1 1 1 DNA polymerase III, delta subunit IstB_IS21 PF01695.12 CDI85581.1 - 0.021 14.2 0.0 0.059 12.7 0.0 1.7 2 0 0 2 2 2 0 IstB-like ATP binding protein T2SE PF00437.15 CDI85581.1 - 0.024 13.5 0.0 0.042 12.7 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_33 PF13671.1 CDI85581.1 - 0.024 14.5 0.0 0.073 12.9 0.0 1.9 2 0 0 2 2 1 0 AAA domain ABC_tran PF00005.22 CDI85581.1 - 0.034 14.4 0.0 0.055 13.7 0.0 1.6 1 1 0 1 1 1 0 ABC transporter RNA_helicase PF00910.17 CDI85581.1 - 0.037 14.2 0.6 0.29 11.3 0.4 2.3 1 1 0 1 1 1 0 RNA helicase Bac_DnaA PF00308.13 CDI85581.1 - 0.043 13.4 0.0 0.1 12.2 0.0 1.6 1 0 0 1 1 1 0 Bacterial dnaA protein PduV-EutP PF10662.4 CDI85581.1 - 0.052 13.0 0.0 0.36 10.2 0.0 2.1 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF815 PF05673.8 CDI85581.1 - 0.074 11.9 0.0 0.21 10.4 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_3 PF07726.6 CDI85581.1 - 0.084 12.4 0.1 5 6.7 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF258 PF03193.11 CDI85581.1 - 0.1 11.7 0.0 0.17 11.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 P63C PF10546.4 CDI85581.1 - 0.12 12.2 0.2 1.6 8.7 0.0 2.6 3 0 0 3 3 2 0 P63C domain DUF87 PF01935.12 CDI85581.1 - 0.15 11.8 1.4 0.31 10.8 0.2 2.3 2 1 0 2 2 2 0 Domain of unknown function DUF87 PAT1 PF09770.4 CDI85582.1 - 0.22 9.7 69.6 0.23 9.6 48.3 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Plasmodium_Vir PF05795.6 CDI85582.1 - 0.26 10.4 12.3 0.42 9.7 8.5 1.4 1 0 0 1 1 1 0 Plasmodium vivax Vir protein CDC27 PF09507.5 CDI85582.1 - 0.71 9.0 32.4 0.84 8.7 22.5 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Presenilin PF01080.12 CDI85582.1 - 2.2 7.0 19.0 2.4 6.8 13.2 1.2 1 0 0 1 1 1 0 Presenilin Herpes_env PF01673.13 CDI85582.1 - 4.6 5.6 19.8 4.9 5.5 13.7 1.2 1 0 0 1 1 1 0 Herpesvirus putative major envelope glycoprotein Raftlin PF15250.1 CDI85582.1 - 5.1 5.5 30.1 5.7 5.3 20.9 1.2 1 0 0 1 1 1 0 Raftlin DUF2347 PF09804.4 CDI85583.1 - 0.022 14.0 5.6 0.046 12.9 3.9 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2347) Suf PF05843.9 CDI85584.1 - 0.03 14.0 28.0 0.036 13.8 19.4 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) His_Phos_2 PF00328.17 CDI85584.1 - 0.045 13.0 11.8 0.052 12.8 8.1 1.0 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 2) TP53IP5 PF15331.1 CDI85584.1 - 0.14 12.0 19.8 0.17 11.7 13.7 1.1 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 GAGA_bind PF06217.7 CDI85584.1 - 0.17 11.8 18.5 0.19 11.6 12.8 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family DUF4045 PF13254.1 CDI85584.1 - 0.35 10.1 18.2 0.38 9.9 12.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) CMV_1a PF12467.3 CDI85584.1 - 0.88 9.9 14.6 1.1 9.6 10.1 1.1 1 0 0 1 1 1 0 Cucumber mosaic virus 1a protein family DUF3807 PF12720.2 CDI85584.1 - 1.6 8.8 23.1 2.1 8.4 16.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) CDC45 PF02724.9 CDI85584.1 - 1.8 6.5 18.0 2 6.3 12.5 1.0 1 0 0 1 1 1 0 CDC45-like protein DUF605 PF04652.11 CDI85584.1 - 2 7.7 25.3 2.7 7.2 17.6 1.3 1 0 0 1 1 1 0 Vta1 like DUF2076 PF09849.4 CDI85584.1 - 2.2 8.2 32.0 2.5 8.1 22.2 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Apt1 PF10351.4 CDI85584.1 - 2.8 6.6 19.0 3.2 6.4 13.2 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Neur_chan_memb PF02932.11 CDI85584.1 - 3 7.6 17.5 3.6 7.4 12.1 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Presenilin PF01080.12 CDI85584.1 - 3.2 6.4 15.0 3.7 6.2 10.4 1.1 1 0 0 1 1 1 0 Presenilin NARP1 PF12569.3 CDI85584.1 - 3.6 6.2 14.4 4.9 5.7 10.0 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 AUX_IAA PF02309.11 CDI85584.1 - 3.8 7.1 20.2 4.4 6.9 14.0 1.1 1 0 0 1 1 1 0 AUX/IAA family PAT1 PF09770.4 CDI85584.1 - 3.9 5.5 45.7 4.4 5.4 31.6 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Raftlin PF15250.1 CDI85584.1 - 4.6 5.6 18.1 5.2 5.4 12.6 1.1 1 0 0 1 1 1 0 Raftlin MRP-S26 PF14943.1 CDI85584.1 - 4.8 6.7 23.7 6.6 6.2 16.4 1.1 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 Zip PF02535.17 CDI85584.1 - 4.8 6.0 6.2 5.8 5.8 4.3 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Rtf2 PF04641.7 CDI85584.1 - 5.2 6.1 20.1 6.1 5.9 13.9 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger DUF1675 PF07897.6 CDI85584.1 - 5.3 6.8 20.8 6.2 6.5 14.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) MRP-S31 PF15433.1 CDI85584.1 - 6.2 6.1 22.7 7.5 5.8 15.7 1.1 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 Totivirus_coat PF05518.6 CDI85584.1 - 6.8 4.3 8.5 7.1 4.3 5.9 1.0 1 0 0 1 1 1 0 Totivirus coat protein BTV_NS2 PF04514.7 CDI85584.1 - 8 5.2 16.8 9.2 5.0 11.6 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Hid1 PF12722.2 CDI85584.1 - 8.2 3.9 25.3 9.1 3.8 17.5 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein FLO_LFY PF01698.11 CDI85584.1 - 9.2 4.9 19.7 11 4.7 13.7 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein Ycf1 PF05758.7 CDI85584.1 - 9.3 3.8 18.8 10 3.6 13.1 1.1 1 0 0 1 1 1 0 Ycf1 Baculo_helicase PF04735.7 CDI85585.1 - 2.6 5.2 12.3 0.58 7.4 6.3 1.4 1 1 0 1 1 1 0 Baculovirus DNA helicase DUF1917 PF08939.5 CDI85585.1 - 2.8 7.5 18.2 3.6 7.2 12.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1917) DUF4463 PF14703.1 CDI85585.1 - 3.8 8.1 10.2 0.068 13.7 1.2 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4463) DUF4613 PF15390.1 CDI85585.1 - 5.1 5.1 22.8 7.7 4.5 15.8 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4613) DUF2183 PF09949.4 CDI85587.1 - 0.028 14.3 0.0 0.082 12.8 0.0 1.8 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2183) DUF4557 PF15101.1 CDI85587.1 - 0.065 13.0 10.1 0.11 12.2 7.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) PAT1 PF09770.4 CDI85587.1 - 0.19 9.9 31.7 0.29 9.3 22.0 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Suf PF05843.9 CDI85587.1 - 0.26 11.0 9.8 0.46 10.1 6.8 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Med15 PF09606.5 CDI85587.1 - 0.36 8.9 40.1 0.61 8.2 27.8 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Shisa PF13908.1 CDI85587.1 - 0.6 10.2 9.9 1.2 9.2 6.9 1.4 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Hid1 PF12722.2 CDI85587.1 - 0.63 7.6 6.8 0.88 7.1 4.7 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Ycf1 PF05758.7 CDI85587.1 - 0.67 7.6 5.7 0.96 7.0 3.9 1.1 1 0 0 1 1 1 0 Ycf1 IncA PF04156.9 CDI85587.1 - 1.2 8.6 17.9 2.7 7.5 12.4 1.5 1 0 0 1 1 1 0 IncA protein Borrelia_P83 PF05262.6 CDI85587.1 - 1.2 7.2 7.5 1.8 6.7 5.2 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein eIF-3_zeta PF05091.7 CDI85587.1 - 1.3 7.5 10.8 2 6.9 7.5 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) CPSF100_C PF13299.1 CDI85587.1 - 2 8.5 9.0 3.4 7.8 6.2 1.3 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Serinc PF03348.10 CDI85587.1 - 2.4 6.7 5.0 3.6 6.1 3.4 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) NAD_Gly3P_dh_N PF01210.18 CDI85588.1 - 3.7e-42 143.7 0.0 5.8e-42 143.0 0.0 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.9 CDI85588.1 - 5.3e-32 110.5 0.2 9.1e-32 109.8 0.1 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus F420_oxidored PF03807.12 CDI85588.1 - 0.089 13.2 0.0 0.61 10.5 0.0 2.3 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent PfkB PF00294.19 CDI85589.1 - 1.9e-41 142.1 5.3 1.1e-36 126.4 1.2 2.2 1 1 1 2 2 2 2 pfkB family carbohydrate kinase HEAT_2 PF13646.1 CDI85590.1 - 0.021 15.1 35.5 0.062 13.5 1.7 7.8 7 3 4 11 11 11 0 HEAT repeats HEAT PF02985.17 CDI85590.1 - 0.18 11.9 22.4 2.1 8.6 0.0 7.8 8 0 0 8 8 8 0 HEAT repeat DUF3277 PF11681.3 CDI85590.1 - 0.27 10.7 0.0 1.1 8.6 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3277) HECT PF00632.20 CDI85592.1 - 2.8e-35 122.0 0.0 8.4e-21 74.4 0.0 2.4 1 1 1 2 2 2 2 HECT-domain (ubiquitin-transferase) Ank PF00023.25 CDI85592.1 - 1.7e-11 43.3 0.2 0.0012 18.5 0.0 4.2 3 0 0 3 3 3 3 Ankyrin repeat Ank_2 PF12796.2 CDI85592.1 - 4.7e-10 39.6 0.1 3.1e-08 33.8 0.0 3.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 CDI85592.1 - 1.8e-07 31.4 4.8 0.0018 18.6 0.0 4.4 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 CDI85592.1 - 3.3e-07 30.3 6.4 0.21 11.8 0.0 4.7 3 1 1 4 4 4 3 Ankyrin repeats (many copies) OmpH PF03938.9 CDI85592.1 - 0.00011 22.1 15.8 0.00011 22.1 11.0 11.7 9 2 0 10 10 10 2 Outer membrane protein (OmpH-like) Ribosomal_60s PF00428.14 CDI85592.1 - 0.0011 19.3 12.8 0.0011 19.3 8.8 35.8 31 6 4 35 35 35 2 60s Acidic ribosomal protein Ank_3 PF13606.1 CDI85592.1 - 0.0056 16.7 0.2 79 3.9 0.2 4.5 3 1 0 3 3 3 0 Ankyrin repeat SR-25 PF10500.4 CDI85593.1 - 9.7e-06 25.2 8.7 9.7e-06 25.2 6.1 11.6 6 2 4 11 11 11 2 Nuclear RNA-splicing-associated protein DUF755 PF05501.6 CDI85594.1 - 0.0027 17.7 4.7 0.0027 17.7 3.3 9.2 6 3 1 7 7 7 1 Domain of unknown function (DUF755) DUF342 PF03961.8 CDI85594.1 - 0.019 13.3 5.8 0.03 12.7 4.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) SOBP PF15279.1 CDI85595.1 - 0.57 10.5 9.4 0.66 10.3 6.5 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein PAT1 PF09770.4 CDI85595.1 - 2.4 6.2 40.6 2.8 6.0 28.2 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Exonuc_VII_L PF02601.10 CDI85595.1 - 3.4 6.7 13.1 3.6 6.6 9.1 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF4470 PF14737.1 CDI85596.1 - 0.19 11.4 1.8 26 4.6 0.1 3.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4470) MIP-T3 PF10243.4 CDI85597.1 - 0.0039 15.7 60.2 0.005 15.3 41.7 1.0 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 TFIIF_alpha PF05793.7 CDI85597.1 - 0.27 9.5 46.7 0.41 8.9 32.3 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Daxx PF03344.10 CDI85597.1 - 0.66 8.3 43.5 0.81 8.1 30.2 1.1 1 0 0 1 1 1 0 Daxx Family Macoilin PF09726.4 CDI85597.1 - 0.91 7.7 53.9 1.3 7.2 37.4 1.2 1 0 0 1 1 1 0 Transmembrane protein Utp14 PF04615.8 CDI85597.1 - 1.7 6.7 50.3 2.2 6.3 34.9 1.1 1 0 0 1 1 1 0 Utp14 protein PLRV_ORF5 PF01690.12 CDI85597.1 - 2 7.5 44.5 2.4 7.1 30.9 1.0 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein PAT1 PF09770.4 CDI85598.1 - 1.9 6.6 126.7 0.038 12.2 80.4 2.0 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 Surface_antigen PF11054.3 CDI85599.1 - 1.8e-05 24.2 0.4 7.4e-05 22.2 0.3 1.9 1 1 0 1 1 1 1 Sporozoite TA4 surface antigen eIF-3_zeta PF05091.7 CDI85599.1 - 0.15 10.6 18.0 0.19 10.3 12.5 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Pox_Ag35 PF03286.9 CDI85599.1 - 0.17 11.3 7.8 0.21 11.0 5.4 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein PAT1 PF09770.4 CDI85599.1 - 0.23 9.6 46.7 0.27 9.4 32.4 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF4220 PF13968.1 CDI85599.1 - 0.33 10.0 4.9 0.36 9.8 3.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4220) DUF4175 PF13779.1 CDI85599.1 - 0.34 8.5 39.4 0.37 8.4 27.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Herpes_UL87 PF03043.9 CDI85599.1 - 0.35 9.2 9.6 0.41 8.9 6.6 1.0 1 0 0 1 1 1 0 Herpesvirus UL87 family DUF4045 PF13254.1 CDI85599.1 - 0.68 9.1 16.9 0.82 8.8 11.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) RR_TM4-6 PF06459.7 CDI85599.1 - 0.83 9.4 13.6 1 9.2 9.4 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF4638 PF15472.1 CDI85599.1 - 1.3 8.5 10.1 1.7 8.1 7.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) Hid1 PF12722.2 CDI85599.1 - 3.1 5.3 19.9 3.4 5.2 13.8 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SPX PF03105.14 CDI85599.1 - 3.1 7.5 18.1 3.8 7.2 12.5 1.1 1 0 0 1 1 1 0 SPX domain LMBR1 PF04791.11 CDI85599.1 - 3.5 6.1 7.3 3.7 6.0 5.0 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF1510 PF07423.6 CDI85599.1 - 3.7 6.8 17.0 4.8 6.5 11.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Lin-8 PF03353.10 CDI85599.1 - 4.2 6.5 21.3 5 6.3 14.8 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist DUF4647 PF15504.1 CDI85599.1 - 4.3 6.0 27.0 5.2 5.8 18.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4647) Med15 PF09606.5 CDI85599.1 - 4.5 5.3 58.0 5.4 5.0 40.2 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal CKAP2_C PF15297.1 CDI85599.1 - 4.9 5.8 19.7 6.9 5.3 13.7 1.1 1 0 0 1 1 1 0 Cytoskeleton-associated protein 2 C-terminus Neur_chan_memb PF02932.11 CDI85599.1 - 6.9 6.4 20.7 9.7 5.9 14.4 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region CDK5_activator PF03261.10 CDI85599.1 - 8.4 5.6 17.1 14 4.9 11.9 1.4 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein FAM60A PF15396.1 CDI85599.1 - 8.6 6.0 20.5 12 5.5 14.2 1.2 1 0 0 1 1 1 0 Protein Family FAM60A RF-1 PF00472.15 CDI85600.1 - 5.3e-10 39.1 10.5 5.3e-10 39.1 7.2 2.2 2 0 0 2 2 2 1 RF-1 domain PAT1 PF09770.4 CDI85600.1 - 0.12 10.5 27.9 0.17 10.1 19.3 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Spore_coat_CotO PF14153.1 CDI85600.1 - 8.9 5.7 23.2 5.3 6.4 9.1 2.3 2 0 0 2 2 2 0 Spore coat protein CotO HemX PF04375.9 CDI85601.1 - 0.0048 15.5 34.6 0.0061 15.1 24.0 1.0 1 0 0 1 1 1 1 HemX Med15 PF09606.5 CDI85601.1 - 0.0088 14.3 48.7 0.011 14.0 33.7 1.0 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal PIG-U PF06728.8 CDI85601.1 - 0.043 12.6 0.4 0.05 12.4 0.3 1.2 1 0 0 1 1 1 0 GPI transamidase subunit PIG-U PAT1 PF09770.4 CDI85601.1 - 0.13 10.4 32.8 0.14 10.3 22.8 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF4131 PF13567.1 CDI85601.1 - 0.17 11.2 4.7 0.25 10.7 3.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) SID-1_RNA_chan PF13965.1 CDI85601.1 - 0.38 8.8 5.3 0.42 8.7 3.7 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 EphA2_TM PF14575.1 CDI85601.1 - 0.41 11.0 0.1 0.41 11.0 0.1 2.6 2 1 1 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain FHIPEP PF00771.15 CDI85601.1 - 0.5 8.6 19.2 0.66 8.2 13.3 1.1 1 0 0 1 1 1 0 FHIPEP family Peptidase_S49_N PF08496.5 CDI85601.1 - 0.54 10.0 12.7 0.045 13.5 5.5 1.6 2 0 0 2 2 2 0 Peptidase family S49 N-terminal TFIIA PF03153.8 CDI85601.1 - 1.4 8.7 31.8 1.6 8.5 22.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Glyco_hydro_1 PF00232.13 CDI85601.1 - 1.4 7.0 7.3 1.7 6.7 5.0 1.0 1 0 0 1 1 1 0 Glycosyl hydrolase family 1 COX6A PF02046.10 CDI85601.1 - 3.2 7.6 9.3 8.7 6.3 6.5 1.8 1 1 0 1 1 1 0 Cytochrome c oxidase subunit VIa DUF4446 PF14584.1 CDI85601.1 - 4.6 7.0 9.1 6 6.6 5.8 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF4446) DUF342 PF03961.8 CDI85601.1 - 4.7 5.5 11.3 5.2 5.3 7.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Endonuc_Holl PF10107.4 CDI85601.1 - 7.2 6.2 12.9 13 5.4 8.9 1.5 1 0 0 1 1 1 0 Endonuclease related to archaeal Holliday junction resolvase Nha1_C PF08619.5 CDI85603.1 - 0.0024 17.2 18.3 0.0024 17.2 12.7 2.0 2 0 0 2 2 2 1 Alkali metal cation/H+ antiporter Nha1 C terminus DUF2967 PF11179.3 CDI85603.1 - 0.0037 16.8 9.1 0.0037 16.8 6.3 3.9 2 1 0 2 2 2 1 Protein of unknown function (DUF2967) Macoilin PF09726.4 CDI85603.1 - 0.65 8.2 32.6 1 7.5 22.6 1.3 1 0 0 1 1 1 0 Transmembrane protein DUF572 PF04502.8 CDI85603.1 - 1.6 7.8 32.1 8.3 5.5 19.0 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF572) Herpes_UL87 PF03043.9 CDI85603.1 - 1.7 6.9 14.4 2.8 6.2 10.0 1.4 1 1 0 1 1 1 0 Herpesvirus UL87 family SAGA-Tad1 PF12767.2 CDI85603.1 - 1.9 8.1 40.9 0.77 9.3 20.8 2.2 2 0 0 2 2 2 0 Transcriptional regulator of RNA polII, SAGA, subunit FLO_LFY PF01698.11 CDI85603.1 - 2.2 7.0 28.6 0.27 10.0 15.2 2.1 2 0 0 2 2 2 0 Floricaula / Leafy protein Ribosomal_60s PF00428.14 CDI85603.1 - 2.3 8.6 19.5 4.2 7.8 7.0 2.7 2 0 0 2 2 2 0 60s Acidic ribosomal protein Neur_chan_memb PF02932.11 CDI85603.1 - 8 6.2 25.7 14 5.5 15.4 2.1 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region DUF4175 PF13779.1 CDI85603.1 - 9.2 3.8 89.1 3.2 5.3 50.6 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4175) PAT1 PF09770.4 CDI85604.1 - 0.71 8.0 70.5 0.86 7.7 48.9 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Pox_Ag35 PF03286.9 CDI85604.1 - 5.7 6.4 18.3 3.3 7.1 7.5 2.1 2 0 0 2 2 2 0 Pox virus Ag35 surface protein PAT1 PF09770.4 CDI85605.1 - 0.0039 15.5 42.9 0.0044 15.3 29.8 1.1 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 CAF-1_p150 PF11600.3 CDI85605.1 - 0.0058 16.0 36.8 0.024 14.0 25.5 1.8 1 1 0 1 1 1 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal SOBP PF15279.1 CDI85605.1 - 0.32 11.3 26.3 0.47 10.7 18.2 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein Hid1 PF12722.2 CDI85605.1 - 0.97 7.0 23.4 1.2 6.7 16.2 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein HemX PF04375.9 CDI85605.1 - 1.2 7.6 39.6 0.25 9.8 15.6 2.1 2 0 0 2 2 2 0 HemX AUX_IAA PF02309.11 CDI85605.1 - 2 8.1 17.7 3.3 7.3 12.3 1.5 1 0 0 1 1 1 0 AUX/IAA family Strabismus PF06638.6 CDI85605.1 - 7 4.8 12.2 0.012 13.9 0.6 1.8 2 0 0 2 2 2 0 Strabismus protein Paramyxo_ncap PF00973.14 CDI85605.1 - 7.5 5.1 16.6 11 4.5 11.5 1.4 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein HdeA PF06411.6 CDI85605.1 - 8.4 6.4 17.6 0.16 11.9 0.6 2.7 2 0 0 2 2 2 0 HdeA/HdeB family BTV_NS2 PF04514.7 CDI85605.1 - 9.3 5.0 17.6 13 4.5 12.2 1.2 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 BAF1_ABF1 PF04684.8 CDI85606.1 - 0.16 10.8 28.9 0.18 10.6 20.0 1.0 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor CDK2AP PF09806.4 CDI85606.1 - 0.83 9.8 20.9 1.1 9.4 14.5 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein Lipase PF00151.14 CDI85606.1 - 1.2 8.2 11.3 1.3 8.1 7.8 1.0 1 0 0 1 1 1 0 Lipase Herpes_env PF01673.13 CDI85606.1 - 1.8 7.0 13.9 1.9 6.9 9.6 1.0 1 0 0 1 1 1 0 Herpesvirus putative major envelope glycoprotein MAT1 PF06391.8 CDI85606.1 - 4.6 6.7 16.4 5.9 6.4 11.3 1.2 1 0 0 1 1 1 0 CDK-activating kinase assembly factor MAT1 DUF3474 PF11960.3 CDI85606.1 - 4.6 7.2 6.7 5.5 7.0 4.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3474) SR-25 PF10500.4 CDI85606.1 - 4.8 6.5 26.5 9.7 5.5 18.4 1.5 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein Mcm10 PF09332.6 CDI85606.1 - 5.5 6.2 20.6 5.9 6.1 14.3 1.1 1 0 0 1 1 1 0 Mcm10 replication factor Plasmodium_Vir PF05795.6 CDI85606.1 - 5.7 6.0 6.5 7.5 5.6 4.5 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein G-alpha PF00503.15 CDI85606.1 - 6.3 5.3 13.8 7 5.2 9.6 1.1 1 0 0 1 1 1 0 G-protein alpha subunit DDHD PF02862.12 CDI85606.1 - 6.4 6.5 15.1 7.4 6.2 10.5 1.2 1 0 0 1 1 1 0 DDHD domain FAM60A PF15396.1 CDI85606.1 - 6.8 6.3 17.3 7.5 6.2 12.0 1.1 1 0 0 1 1 1 0 Protein Family FAM60A Rota_VP2 PF05087.7 CDI85606.1 - 8.2 4.2 11.5 8.5 4.1 8.0 1.0 1 0 0 1 1 1 0 Rotavirus VP2 protein CDC45 PF02724.9 CDI85606.1 - 9 4.1 14.0 11 3.9 9.7 1.1 1 0 0 1 1 1 0 CDC45-like protein PDGF_N PF04692.8 CDI85606.1 - 9.3 6.8 11.4 6.5 7.3 0.5 2.1 2 0 0 2 2 2 0 Platelet-derived growth factor, N terminal region FCP1_C PF09309.5 CDI85607.1 - 0.0024 17.2 14.1 0.0024 17.2 9.8 3.3 1 1 2 3 3 3 1 FCP1, C-terminal PAT1 PF09770.4 CDI85607.1 - 0.0081 14.4 69.4 0.0087 14.3 48.1 1.3 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 LMBR1 PF04791.11 CDI85607.1 - 1.7 7.1 10.0 2.2 6.7 6.9 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Macoilin PF09726.4 CDI85607.1 - 3.3 5.8 45.0 3.8 5.6 31.2 1.1 1 0 0 1 1 1 0 Transmembrane protein Asp-B-Hydro_N PF05279.6 CDI85607.1 - 5.3 6.8 20.7 6.7 6.4 14.4 1.3 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Daxx PF03344.10 CDI85607.1 - 6.2 5.1 35.2 6.6 5.0 24.4 1.0 1 0 0 1 1 1 0 Daxx Family CAF-1_p150 PF11600.3 CDI85608.1 - 7.7 5.8 7.3 3.1 7.0 2.5 1.9 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF1510 PF07423.6 CDI85609.1 - 1.6 8.0 17.2 1.8 7.9 11.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DUF4192 PF13830.1 CDI85609.1 - 2.3 7.8 8.3 2.6 7.6 5.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4192) Herpes_DNAp_acc PF04929.7 CDI85609.1 - 5.4 5.8 14.3 6.1 5.7 9.9 1.0 1 0 0 1 1 1 0 Herpes DNA replication accessory factor AUX_IAA PF02309.11 CDI85609.1 - 5.7 6.6 13.0 6.4 6.4 9.0 1.2 1 0 0 1 1 1 0 AUX/IAA family UPF0172 PF03665.8 CDI85609.1 - 6 6.3 8.0 7.1 6.0 5.5 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0172) DUF966 PF06136.8 CDI85610.1 - 0.079 12.3 27.6 0.11 11.9 19.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Peptidase_M56 PF05569.6 CDI85610.1 - 0.084 11.8 2.1 0.11 11.3 1.4 1.2 1 0 0 1 1 1 0 BlaR1 peptidase M56 N6_N4_Mtase PF01555.13 CDI85610.1 - 0.14 11.6 2.1 0.55 9.6 1.5 1.9 1 1 0 1 1 1 0 DNA methylase Ribosomal_S2 PF00318.15 CDI85610.1 - 0.15 11.2 4.9 0.23 10.6 3.4 1.3 1 0 0 1 1 1 0 Ribosomal protein S2 DUF1777 PF08648.7 CDI85610.1 - 0.6 9.8 71.2 25 4.5 49.4 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1777) Trypan_PARP PF05887.6 CDI85610.1 - 1.2 8.9 7.0 1.8 8.3 4.8 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) AAA_23 PF13476.1 CDI85610.1 - 2 8.6 29.6 2.7 8.2 20.5 1.2 1 0 0 1 1 1 0 AAA domain Allexi_40kDa PF05549.6 CDI85610.1 - 2.9 7.1 10.6 4.8 6.3 7.4 1.3 1 0 0 1 1 1 0 Allexivirus 40kDa protein DUF4512 PF14975.1 CDI85610.1 - 6.9 7.5 14.1 0.3 11.9 3.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4512) Bul1_C PF04426.7 CDI85611.1 - 2.3 7.3 15.1 0.13 11.4 1.6 2.2 2 0 0 2 2 2 0 Bul1 C terminus Zip PF02535.17 CDI85612.1 - 0.056 12.4 2.7 0.079 11.9 1.9 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Pex14_N PF04695.8 CDI85612.1 - 0.07 13.1 5.7 0.023 14.7 1.8 1.8 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Spc7_N PF15402.1 CDI85612.1 - 0.11 10.5 4.6 0.15 10.0 3.2 1.1 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 PP1_bind PF15276.1 CDI85612.1 - 0.47 10.5 2.4 1.2 9.1 1.7 1.7 1 0 0 1 1 1 0 Protein phosphatase 1 binding Suf PF05843.9 CDI85612.1 - 0.73 9.5 3.9 0.88 9.2 2.7 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) PAT1 PF09770.4 CDI85612.1 - 2.1 6.5 16.4 2.6 6.1 11.4 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 LETM1 PF07766.8 CDI85613.1 - 1.1e-37 129.5 1.2 1.1e-37 129.5 0.8 2.1 2 0 0 2 2 2 1 LETM1-like protein Chorion_2 PF03964.10 CDI85613.1 - 3.4 8.2 13.1 0.35 11.4 3.7 3.1 2 1 0 2 2 2 0 Chorion family 2 Peptidase_S64 PF08192.6 CDI85613.1 - 7.8 4.7 12.1 13 3.9 8.4 1.3 1 0 0 1 1 1 0 Peptidase family S64 DUF1510 PF07423.6 CDI85614.1 - 2.9 7.1 8.1 3.9 6.7 5.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) PrsW-protease PF13367.1 CDI85615.1 - 1.1 8.4 10.0 0.32 10.1 1.2 2.8 3 1 0 3 3 3 0 Protease prsW family Inhibitor_I71 PF12628.2 CDI85615.1 - 2 8.0 4.8 2.6 7.6 1.4 2.2 2 0 0 2 2 2 0 Falstatin, cysteine peptidase inhibitor Kinase-like PF14531.1 CDI85616.1 - 1e-10 41.1 0.0 1.2e-10 40.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase PF00069.20 CDI85616.1 - 8.3e-08 31.6 0.0 1.5e-07 30.8 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDI85616.1 - 7.1e-06 25.2 0.0 1.1e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase SR-25 PF10500.4 CDI85619.1 - 0.0024 17.3 8.7 0.0024 17.3 6.0 2.2 2 0 0 2 2 2 2 Nuclear RNA-splicing-associated protein DUF4614 PF15391.1 CDI85619.1 - 0.77 9.4 17.3 0.031 14.0 4.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4614) DUF4207 PF13904.1 CDI85619.1 - 6 6.1 23.9 0.44 9.8 5.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4207) SR-25 PF10500.4 CDI85620.1 - 0.00099 18.6 2.0 0.00099 18.6 1.4 4.7 5 0 0 5 5 5 3 Nuclear RNA-splicing-associated protein Pex14_N PF04695.8 CDI85620.1 - 0.16 12.0 0.1 0.16 12.0 0.0 5.1 2 1 1 4 4 4 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Orthopox_A36R PF05950.6 CDI85620.1 - 0.35 10.7 0.1 0.35 10.7 0.1 3.9 3 1 1 4 4 4 0 Orthopoxvirus A36R protein Phostensin_N PF13916.1 CDI85621.1 - 0.35 10.8 5.3 0.92 9.5 1.7 2.6 2 0 0 2 2 2 0 PP1-regulatory protein, Phostensin N-terminal Utp14 PF04615.8 CDI85622.1 - 6.2 4.8 29.7 7.9 4.5 20.6 1.1 1 0 0 1 1 1 0 Utp14 protein DUF1510 PF07423.6 CDI85624.1 - 0.035 13.4 26.4 0.036 13.4 18.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) TRAP_alpha PF03896.11 CDI85624.1 - 0.18 10.7 9.1 0.2 10.6 6.3 1.0 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Peptidase_S49_N PF08496.5 CDI85624.1 - 1.4 8.7 26.5 1.6 8.5 18.4 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF4512 PF14975.1 CDI85624.1 - 1.4 9.8 14.8 2.1 9.2 10.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4512) Zip PF02535.17 CDI85624.1 - 1.6 7.6 13.1 1.6 7.6 9.1 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Folate_carrier PF01770.13 CDI85624.1 - 2.7 6.4 17.0 3.1 6.1 11.8 1.2 1 0 0 1 1 1 0 Reduced folate carrier Herpes_DNAp_acc PF04929.7 CDI85624.1 - 4 6.2 21.6 4.6 6.0 15.0 1.0 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Neur PF00064.13 CDI85624.1 - 4.2 5.3 10.2 4.5 5.2 7.1 1.0 1 0 0 1 1 1 0 Neuraminidase DUF4446 PF14584.1 CDI85624.1 - 4.4 7.1 20.5 5.1 6.9 14.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) Rtf2 PF04641.7 CDI85624.1 - 4.5 6.4 26.9 5.2 6.1 18.7 1.0 1 0 0 1 1 1 0 Rtf2 RING-finger Paf1 PF03985.8 CDI85624.1 - 5.4 5.6 31.1 6.7 5.3 21.6 1.1 1 0 0 1 1 1 0 Paf1 CDC45 PF02724.9 CDI85624.1 - 6.3 4.6 25.6 6.8 4.5 17.8 1.0 1 0 0 1 1 1 0 CDC45-like protein DUF3449 PF11931.3 CDI85624.1 - 6.5 6.2 25.6 7.8 5.9 17.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3449) DUF913 PF06025.7 CDI85624.1 - 6.7 5.3 16.8 7 5.2 11.6 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) CKAP2_C PF15297.1 CDI85624.1 - 7.7 5.2 28.8 8.1 5.1 19.9 1.0 1 0 0 1 1 1 0 Cytoskeleton-associated protein 2 C-terminus Mem_trans PF03547.13 CDI85624.1 - 8.8 4.5 14.7 9.9 4.3 10.2 1.0 1 0 0 1 1 1 0 Membrane transport protein NARP1 PF12569.3 CDI85624.1 - 9.2 4.8 27.9 10 4.7 19.3 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Spore_coat_CotO PF14153.1 CDI85624.1 - 9.2 5.6 39.0 11 5.4 27.0 1.0 1 0 0 1 1 1 0 Spore coat protein CotO Med15 PF09606.5 CDI85625.1 - 0.34 9.0 48.1 0.35 9.0 33.3 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal BAF1_ABF1 PF04684.8 CDI85627.1 - 1.4e-07 30.8 12.4 1.4e-07 30.8 8.6 17.2 11 6 4 17 17 17 2 BAF1 / ABF1 chromatin reorganising factor AP2 PF00847.15 CDI85627.1 - 2.1e-07 30.9 0.6 2.1e-07 30.9 0.4 4.3 5 0 0 5 5 5 1 AP2 domain SAPS PF04499.10 CDI85627.1 - 1.1 7.7 0.0 1.1 7.7 0.0 9.6 5 5 0 6 6 6 0 SIT4 phosphatase-associated protein Phosphoesterase PF04185.9 CDI85628.1 - 6 5.9 11.9 0.057 12.6 2.7 1.7 2 0 0 2 2 2 0 Phosphoesterase family Peptidase_S49_N PF08496.5 CDI85628.1 - 6.4 6.5 9.8 8.6 6.1 2.7 2.3 2 0 0 2 2 2 0 Peptidase family S49 N-terminal MtN3_slv PF03083.11 CDI85629.1 - 2.3e-13 49.8 0.7 3.7e-13 49.1 0.5 1.3 1 0 0 1 1 1 1 Sugar efflux transporter for intercellular exchange SAPS PF04499.10 CDI85629.1 - 3.2 6.2 37.1 7 5.1 6.1 3.2 2 1 0 2 2 2 0 SIT4 phosphatase-associated protein DUF755 PF05501.6 CDI85631.1 - 0.0027 17.7 14.5 0.0027 17.7 10.1 2.4 1 1 1 2 2 1 1 Domain of unknown function (DUF755) DUF572 PF04502.8 CDI85631.1 - 0.1 11.7 6.1 0.13 11.4 4.2 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) DNA_pol_viral_N PF00242.12 CDI85631.1 - 0.2 10.6 15.8 0.25 10.3 10.9 1.1 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain Nha1_C PF08619.5 CDI85631.1 - 0.26 10.5 14.1 0.35 10.1 9.8 1.1 1 0 0 1 1 1 0 Alkali metal cation/H+ antiporter Nha1 C terminus Macoilin PF09726.4 CDI85631.1 - 0.28 9.4 18.5 0.34 9.1 12.8 1.1 1 0 0 1 1 1 0 Transmembrane protein DUF566 PF04484.7 CDI85631.1 - 0.45 9.9 19.1 0.56 9.6 13.2 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF566) Mem_trans PF03547.13 CDI85631.1 - 0.66 8.2 4.1 0.87 7.8 2.9 1.2 1 0 0 1 1 1 0 Membrane transport protein Sec3_C PF09763.4 CDI85631.1 - 1.6 6.7 8.9 1.9 6.5 6.2 1.1 1 0 0 1 1 1 0 Exocyst complex component Sec3 DUF2146 PF10220.4 CDI85631.1 - 2.6 5.9 8.1 2.9 5.7 5.6 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2146) Spc7_N PF15402.1 CDI85631.1 - 3 5.7 21.8 3.7 5.4 15.1 1.0 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 Apt1 PF10351.4 CDI85631.1 - 4 6.1 16.9 5.2 5.8 11.7 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain SOG2 PF10428.4 CDI85631.1 - 5.5 5.5 19.5 6.3 5.3 13.5 1.0 1 0 0 1 1 1 0 RAM signalling pathway protein SprA-related PF12118.3 CDI85632.1 - 0.0005 19.4 24.6 0.00061 19.2 17.1 1.3 1 0 0 1 1 1 1 SprA-related family PAT1 PF09770.4 CDI85632.1 - 0.0037 15.6 34.4 0.0036 15.6 23.8 1.0 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 Med15 PF09606.5 CDI85632.1 - 0.008 14.4 54.2 0.0091 14.2 37.5 1.1 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal RR_TM4-6 PF06459.7 CDI85632.1 - 0.0093 15.8 10.2 0.012 15.5 7.1 1.1 1 0 0 1 1 1 1 Ryanodine Receptor TM 4-6 Activator_LAG-3 PF11498.3 CDI85632.1 - 0.043 12.5 57.3 0.052 12.3 39.7 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Galactosyl_T PF01762.16 CDI85632.1 - 0.052 13.1 1.7 0.19 11.3 1.3 1.8 2 0 0 2 2 2 0 Galactosyltransferase DOR PF14839.1 CDI85632.1 - 0.1 12.3 18.1 0.12 12.1 12.6 1.2 1 0 0 1 1 1 0 DOR family RIC3 PF15361.1 CDI85632.1 - 0.13 12.4 11.3 0.24 11.6 7.8 1.4 1 0 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 FLO_LFY PF01698.11 CDI85632.1 - 0.15 10.8 9.4 0.16 10.7 6.5 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein FimP PF09766.4 CDI85632.1 - 0.17 10.9 28.4 0.2 10.7 19.7 1.0 1 0 0 1 1 1 0 Fms-interacting protein Cellulose_synt PF03552.9 CDI85632.1 - 0.37 9.0 9.0 0.45 8.7 6.2 1.1 1 0 0 1 1 1 0 Cellulose synthase ABC2_membrane_3 PF12698.2 CDI85632.1 - 0.48 9.3 3.3 0.52 9.3 2.3 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein Suf PF05843.9 CDI85632.1 - 0.48 10.0 17.7 0.71 9.5 12.3 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) TFIIA PF03153.8 CDI85632.1 - 0.7 9.7 27.5 0.81 9.5 19.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit 2OG-FeII_Oxy_5 PF13759.1 CDI85632.1 - 0.88 9.8 5.4 1.8 8.8 3.8 1.6 1 1 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase LETM1 PF07766.8 CDI85632.1 - 0.88 8.5 14.1 1.3 8.0 9.8 1.2 1 0 0 1 1 1 0 LETM1-like protein HemX PF04375.9 CDI85632.1 - 1 7.8 29.8 1.3 7.5 20.7 1.1 1 0 0 1 1 1 0 HemX DUF4045 PF13254.1 CDI85632.1 - 1.2 8.2 9.7 1.4 8.0 6.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Serinc PF03348.10 CDI85632.1 - 1.4 7.5 11.2 1.8 7.2 7.8 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) AUX_IAA PF02309.11 CDI85632.1 - 1.6 8.4 10.6 2 8.1 7.3 1.1 1 0 0 1 1 1 0 AUX/IAA family Peroxin-13_N PF04088.8 CDI85632.1 - 1.8 8.5 5.9 2.3 8.1 4.1 1.3 1 0 0 1 1 1 0 Peroxin 13, N-terminal region DUF342 PF03961.8 CDI85632.1 - 2.2 6.6 10.8 2.6 6.3 7.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DDHD PF02862.12 CDI85632.1 - 3.1 7.5 11.1 3.8 7.2 7.7 1.1 1 0 0 1 1 1 0 DDHD domain Dala_Dala_lig_N PF01820.16 CDI85632.1 - 3.6 7.9 8.1 5.6 7.3 5.6 1.3 1 0 0 1 1 1 0 D-ala D-ala ligase N-terminus RNA_pol_Rpb1_5 PF04998.12 CDI85632.1 - 4.3 6.5 11.9 5.7 6.1 8.3 1.1 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 DUF822 PF05687.8 CDI85632.1 - 4.3 7.6 9.8 6.3 7.1 6.8 1.2 1 0 0 1 1 1 0 Plant protein of unknown function (DUF822) CPSF100_C PF13299.1 CDI85632.1 - 4.8 7.3 11.2 6.9 6.8 7.7 1.3 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal 7TM_transglut PF14402.1 CDI85632.1 - 4.9 5.9 9.4 6.8 5.5 6.5 1.2 1 0 0 1 1 1 0 7 transmembrane helices usually fused to an inactive transglutaminase SeqA PF03925.8 CDI85632.1 - 6 6.5 15.4 8.7 6.0 10.7 1.2 1 0 0 1 1 1 0 SeqA protein Bul1_N PF04425.7 CDI85632.1 - 6.4 5.2 14.0 8.3 4.8 9.7 1.1 1 0 0 1 1 1 0 Bul1 N terminus Band_3_cyto PF07565.8 CDI85632.1 - 7 6.0 20.2 9.6 5.6 14.0 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain AAA_23 PF13476.1 CDI85632.1 - 7.4 6.8 22.2 9.8 6.4 15.4 1.1 1 0 0 1 1 1 0 AAA domain SART-1 PF03343.8 CDI85633.1 - 6.8e-52 176.6 84.1 1.5e-37 129.2 44.8 4.3 2 1 0 2 2 2 2 SART-1 family IncA PF04156.9 CDI85633.1 - 3.1e-05 23.6 14.6 3.1e-05 23.6 10.1 4.8 4 1 1 5 5 5 1 IncA protein Med15 PF09606.5 CDI85633.1 - 0.00016 20.0 55.8 0.00016 20.0 38.7 3.1 2 1 0 2 2 2 1 ARC105 or Med15 subunit of Mediator complex non-fungal BAF1_ABF1 PF04684.8 CDI85633.1 - 0.0038 16.1 42.9 0.0038 16.1 29.7 7.4 4 2 2 7 7 7 1 BAF1 / ABF1 chromatin reorganising factor K_trans PF02705.11 CDI85633.1 - 5.4 5.2 7.9 8.7 4.5 5.5 1.2 1 0 0 1 1 1 0 K+ potassium transporter GHMP_kinases_N PF00288.21 CDI85634.1 - 3.3 7.8 17.9 5.7 7.0 0.0 3.4 3 0 0 3 3 3 0 GHMP kinases N terminal domain Herpes_UL87 PF03043.9 CDI85634.1 - 5.1 5.3 9.7 6.1 5.1 6.7 1.2 1 0 0 1 1 1 0 Herpesvirus UL87 family GAGA_bind PF06217.7 CDI85634.1 - 9.1 6.1 19.6 13 5.6 13.6 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family Trehalose_PPase PF02358.11 CDI85636.1 - 2.6e-05 23.2 0.0 2.6e-05 23.2 0.0 2.6 1 1 1 2 2 2 1 Trehalose-phosphatase SAPS PF04499.10 CDI85636.1 - 0.00019 20.1 15.7 0.00023 19.9 10.9 1.3 1 0 0 1 1 1 1 SIT4 phosphatase-associated protein LMBR1 PF04791.11 CDI85636.1 - 0.25 9.8 11.3 0.27 9.7 7.9 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein TFIIA PF03153.8 CDI85636.1 - 6.6 6.5 67.2 3.3 7.5 36.0 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit X PF00739.14 CDI85636.1 - 6.6 6.6 8.4 8.7 6.2 0.0 2.3 2 0 0 2 2 2 0 Trans-activation protein X Mitofilin PF09731.4 CDI85636.1 - 7.1 5.1 44.6 1.9 7.0 0.1 2.2 2 0 0 2 2 2 0 Mitochondrial inner membrane protein SAGA-Tad1 PF12767.2 CDI85636.1 - 8.2 6.0 36.1 0.9 9.1 21.2 2.1 2 0 0 2 2 2 0 Transcriptional regulator of RNA polII, SAGA, subunit APC_CDC26 PF10471.4 CDI85638.1 - 0.045 14.4 0.1 0.045 14.4 0.1 7.3 4 2 0 4 4 4 0 Anaphase-promoting complex APC subunit 1 PAT1 PF09770.4 CDI85639.1 - 9.3 4.3 29.7 11 4.1 20.6 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SR-25 PF10500.4 CDI85640.1 - 0.00031 20.2 7.8 0.00031 20.2 5.4 6.4 5 1 2 7 7 7 2 Nuclear RNA-splicing-associated protein OmpH PF03938.9 CDI85640.1 - 0.63 9.9 0.0 0.63 9.9 0.0 7.2 4 3 0 4 4 4 0 Outer membrane protein (OmpH-like) MDFI PF15316.1 CDI85641.1 - 0.2 11.6 9.8 0.22 11.5 6.8 1.0 1 0 0 1 1 1 0 MyoD family inhibitor SprA-related PF12118.3 CDI85641.1 - 0.37 10.0 35.3 0.49 9.6 24.5 1.1 1 0 0 1 1 1 0 SprA-related family DUF2235 PF09994.4 CDI85641.1 - 0.4 9.9 4.5 0.48 9.7 3.1 1.1 1 0 0 1 1 1 0 Uncharacterized alpha/beta hydrolase domain (DUF2235) DUF2894 PF11445.3 CDI85641.1 - 0.43 10.8 17.2 0.47 10.7 11.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2894) Cellulose_synt PF03552.9 CDI85641.1 - 0.92 7.7 2.7 0.86 7.8 1.9 1.0 1 0 0 1 1 1 0 Cellulose synthase FAM60A PF15396.1 CDI85641.1 - 0.96 9.1 8.4 1 9.0 5.9 1.0 1 0 0 1 1 1 0 Protein Family FAM60A Pex14_N PF04695.8 CDI85641.1 - 1 9.4 18.2 1.4 9.0 12.6 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region R_equi_Vir PF05526.6 CDI85641.1 - 1.5 8.4 7.9 2 7.9 5.5 1.3 1 0 0 1 1 1 0 Rhodococcus equi virulence-associated protein FLO_LFY PF01698.11 CDI85641.1 - 2.1 7.1 11.6 2.2 7.0 8.0 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein Cyclin_C PF02984.14 CDI85641.1 - 2.4 8.1 8.0 3.6 7.5 5.5 1.2 1 0 0 1 1 1 0 Cyclin, C-terminal domain DDHD PF02862.12 CDI85641.1 - 2.7 7.7 9.9 3.2 7.4 6.9 1.0 1 0 0 1 1 1 0 DDHD domain MelC1 PF06236.6 CDI85641.1 - 3.1 7.8 11.4 3.9 7.4 7.9 1.2 1 0 0 1 1 1 0 Tyrosinase co-factor MelC1 Med15 PF09606.5 CDI85641.1 - 5.1 5.1 45.2 6.2 4.8 31.3 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF3450 PF11932.3 CDI85641.1 - 5.2 6.2 28.8 6.4 5.9 19.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) PAT1 PF09770.4 CDI85641.1 - 7.1 4.7 33.0 7.9 4.5 22.8 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Pal1 PF08316.6 CDI85641.1 - 7.2 7.0 8.1 9.2 6.7 5.6 1.1 1 0 0 1 1 1 0 Pal1 cell morphology protein FNIP_N PF14636.1 CDI85641.1 - 7.3 7.0 14.2 8.9 6.7 9.8 1.1 1 0 0 1 1 1 0 Folliculin-interacting protein N-terminus MSP1_C PF07462.6 CDI85641.1 - 9.3 4.5 7.8 10 4.3 5.4 1.0 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Band_3_cyto PF07565.8 CDI85641.1 - 9.3 5.6 12.7 11 5.4 8.8 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain WD40 PF00400.27 CDI85642.1 - 7.3e-07 28.8 0.1 0.0029 17.4 0.0 3.0 2 0 0 2 2 2 2 WD domain, G-beta repeat Apt1 PF10351.4 CDI85642.1 - 2.1 7.1 8.6 0.2 10.4 0.9 2.3 3 0 0 3 3 3 0 Golgi-body localisation protein domain DUF1510 PF07423.6 CDI85645.1 - 1.1e-06 28.1 10.6 1.1e-06 28.1 7.3 3.0 3 0 0 3 3 3 1 Protein of unknown function (DUF1510) IncA PF04156.9 CDI85645.1 - 2.4e-05 24.0 13.5 2.4e-05 24.0 9.4 3.6 3 1 0 3 3 1 1 IncA protein DUF3328 PF11807.3 CDI85645.1 - 0.00012 21.8 0.1 0.00012 21.8 0.0 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF3328) DUF4175 PF13779.1 CDI85645.1 - 0.0013 16.5 17.8 0.0013 16.5 12.4 3.3 3 0 0 3 3 2 1 Domain of unknown function (DUF4175) BRF1 PF07741.8 CDI85645.1 - 0.008 16.3 1.2 0.008 16.3 0.8 4.7 3 1 0 3 3 2 1 Brf1-like TBP-binding domain DUF4131 PF13567.1 CDI85645.1 - 0.0096 15.3 0.4 0.0096 15.3 0.3 3.1 2 1 1 3 3 2 1 Domain of unknown function (DUF4131) FimP PF09766.4 CDI85645.1 - 0.01 14.9 11.5 0.01 14.9 8.0 4.3 3 2 2 5 5 1 0 Fms-interacting protein Ribosomal_60s PF00428.14 CDI85645.1 - 0.017 15.5 7.4 0.017 15.5 5.1 4.7 5 1 0 5 5 2 0 60s Acidic ribosomal protein Kei1 PF08552.6 CDI85645.1 - 0.017 14.8 0.6 0.017 14.8 0.4 4.2 3 1 0 3 3 2 0 Inositolphosphorylceramide synthase subunit Kei1 PBP1_TM PF14812.1 CDI85645.1 - 0.024 14.9 2.0 0.024 14.9 1.4 3.3 2 1 0 2 2 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Cortexin PF11057.3 CDI85645.1 - 0.042 13.4 0.0 0.1 12.1 0.0 1.7 1 0 0 1 1 1 0 Cortexin of kidney SDA1 PF05285.7 CDI85645.1 - 2.6 7.2 48.3 1.2 8.3 26.6 2.2 1 1 1 2 2 1 0 SDA1 Ilm1 PF10311.4 CDI85646.1 - 0.14 11.6 0.4 0.25 10.8 0.3 1.4 1 0 0 1 1 1 0 Increased loss of mitochondrial DNA protein 1 DUF2217 PF10265.4 CDI85646.1 - 0.76 8.4 29.2 0.091 11.5 3.5 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2217) Phostensin_N PF13916.1 CDI85646.1 - 5.5 7.0 10.1 0.6 10.1 3.0 2.2 2 0 0 2 2 2 0 PP1-regulatory protein, Phostensin N-terminal DUF3682 PF12446.3 CDI85647.1 - 0.38 11.0 19.3 0.53 10.5 13.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) Suf PF05843.9 CDI85647.1 - 5.7 6.5 16.8 6.8 6.3 11.7 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DDHD PF02862.12 CDI85647.1 - 5.8 6.6 13.7 7.2 6.3 9.5 1.1 1 0 0 1 1 1 0 DDHD domain RRM_1 PF00076.17 CDI85651.1 - 1.4e-14 53.5 0.0 2.3e-14 52.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CDI85651.1 - 8.4e-12 44.8 0.0 1.5e-11 44.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CDI85651.1 - 3.9e-06 26.6 0.0 5.9e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ctr PF04145.10 CDI85653.1 - 9.9e-07 28.9 0.6 1.6e-06 28.2 0.4 1.3 1 0 0 1 1 1 1 Ctr copper transporter family GLTP PF08718.6 CDI85654.1 - 2.7e-23 82.6 0.0 3.3e-23 82.3 0.0 1.1 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) UQ_con PF00179.21 CDI85656.1 - 4.1e-45 152.6 0.0 4.9e-45 152.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 CDI85656.1 - 0.027 14.2 0.0 0.037 13.7 0.0 1.4 1 1 0 1 1 1 0 Prokaryotic E2 family B RWD PF05773.17 CDI85656.1 - 0.033 14.0 0.2 0.052 13.4 0.1 1.6 1 1 0 1 1 1 0 RWD domain SNF2_N PF00176.18 CDI85657.1 - 5.8e-53 179.6 0.1 7.5e-27 93.8 0.0 3.4 3 0 0 3 3 3 3 SNF2 family N-terminal domain Helicase_C PF00271.26 CDI85657.1 - 1.2e-07 31.4 0.0 3.6e-07 29.9 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-PARP PF00645.13 CDI85657.1 - 4.7e-07 29.9 0.2 1.8e-06 28.0 0.1 2.1 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region zf-RING_2 PF13639.1 CDI85657.1 - 0.00033 20.4 6.6 0.001 18.8 0.1 3.4 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.20 CDI85657.1 - 0.011 15.3 0.1 0.011 15.3 0.1 3.5 4 0 0 4 4 4 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 CDI85657.1 - 0.024 14.7 5.2 0.17 11.9 0.0 3.3 3 0 0 3 3 3 0 RING-H2 zinc finger Reticulon PF02453.12 CDI85658.1 - 3.9e-10 39.5 0.9 6.2e-10 38.9 0.6 1.4 1 1 0 1 1 1 1 Reticulon UQ_con PF00179.21 CDI85659.1 - 1e-16 60.6 0.0 1.5e-16 60.0 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 CDI85659.1 - 0.05 13.4 0.0 0.082 12.8 0.0 1.3 1 0 0 1 1 1 0 RWD domain Prok-E2_A PF14457.1 CDI85659.1 - 0.58 9.6 2.7 1.6 8.2 1.9 1.7 1 1 0 1 1 1 0 Prokaryotic E2 family A CBM_48 PF02922.13 CDI85660.1 - 6.3e-20 71.0 0.1 1.3e-18 66.8 0.0 3.0 3 0 0 3 3 3 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Alpha-amylase_C PF02806.13 CDI85660.1 - 1.4e-18 66.8 0.0 4.9e-18 65.0 0.0 1.9 2 0 0 2 2 2 1 Alpha amylase, C-terminal all-beta domain Alpha-amylase PF00128.19 CDI85660.1 - 1.8e-17 63.7 0.1 2.8e-08 33.5 0.0 3.1 1 1 1 2 2 2 2 Alpha amylase, catalytic domain PDEase_I PF00233.14 CDI85661.1 - 2.4e-44 151.8 6.6 3.4e-23 82.6 3.0 2.4 2 0 0 2 2 2 2 3'5'-cyclic nucleotide phosphodiesterase GAF_3 PF13492.1 CDI85661.1 - 8.6e-06 25.8 0.0 2.5e-05 24.3 0.0 1.8 1 0 0 1 1 1 1 GAF domain RCC1_2 PF13540.1 CDI85662.1 - 9e-09 34.7 16.1 0.086 12.4 0.3 4.9 4 0 0 4 4 4 4 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.13 CDI85662.1 - 0.0018 18.4 18.5 0.014 15.6 0.0 6.7 7 1 0 7 7 7 3 Regulator of chromosome condensation (RCC1) repeat AAA_17 PF13207.1 CDI85663.1 - 8.8e-05 23.3 0.0 0.00013 22.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 CDI85663.1 - 0.00014 22.1 0.0 0.00019 21.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain ArgK PF03308.11 CDI85663.1 - 0.0053 15.5 0.0 0.0085 14.8 0.0 1.3 1 0 0 1 1 1 1 ArgK protein KTI12 PF08433.5 CDI85663.1 - 0.015 14.5 0.0 0.021 14.0 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_33 PF13671.1 CDI85663.1 - 0.02 14.7 0.0 0.036 13.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 CDI85663.1 - 0.028 14.1 0.0 0.063 13.0 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain Zeta_toxin PF06414.7 CDI85663.1 - 0.046 12.8 0.1 0.071 12.1 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin APS_kinase PF01583.15 CDI85663.1 - 0.096 12.3 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_25 PF13481.1 CDI85663.1 - 0.11 11.8 0.0 0.41 10.0 0.0 1.8 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.16 CDI85663.1 - 0.12 11.5 0.0 0.18 10.9 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI WD40 PF00400.27 CDI85664.1 - 1.8e-23 81.5 10.0 5.2e-06 26.1 0.1 6.4 7 0 0 7 7 7 3 WD domain, G-beta repeat EF-hand_1 PF00036.27 CDI85664.1 - 0.0032 16.6 0.0 0.0073 15.5 0.0 1.6 1 0 0 1 1 1 1 EF hand PQQ PF01011.16 CDI85664.1 - 0.0041 16.5 0.7 23 4.7 0.0 4.4 5 0 0 5 5 5 1 PQQ enzyme repeat PQQ_3 PF13570.1 CDI85664.1 - 3 8.2 5.6 36 4.8 0.0 4.5 6 1 0 6 6 6 0 PQQ-like domain AAA_22 PF13401.1 CDI85665.1 - 0.086 12.9 0.0 0.086 12.9 0.0 3.2 3 0 0 3 3 3 0 AAA domain DUF3357 PF11837.3 CDI85666.1 - 0.081 12.7 10.6 0.69 9.7 2.2 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF3357) DUF3801 PF12687.2 CDI85666.1 - 0.082 12.4 25.4 0.094 12.2 17.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3801) Med15 PF09606.5 CDI85666.1 - 0.66 8.0 60.9 0.77 7.8 42.2 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal BRF1 PF07741.8 CDI85666.1 - 0.85 9.8 21.7 1.8 8.8 4.5 2.2 2 0 0 2 2 2 0 Brf1-like TBP-binding domain Neur_chan_memb PF02932.11 CDI85666.1 - 0.98 9.2 16.6 1.1 9.0 11.5 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF3121 PF11319.3 CDI85666.1 - 1.1 8.7 20.1 0.031 13.7 3.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3121) DivIC PF04977.10 CDI85666.1 - 1.6 8.2 36.6 0.24 10.8 10.3 2.3 2 0 0 2 2 2 0 Septum formation initiator Rsc14 PF08586.5 CDI85666.1 - 3.4 8.2 12.6 0.82 10.1 1.6 2.2 2 0 0 2 2 2 0 RSC complex, Rsc14/Ldb7 subunit Sigma_reg_C PF13791.1 CDI85666.1 - 4.2 7.3 8.6 0.53 10.2 1.1 2.0 2 0 0 2 2 2 0 Sigma factor regulator C-terminal Peroxin-13_N PF04088.8 CDI85666.1 - 5.5 6.9 11.6 1.9 8.4 1.5 2.2 2 0 0 2 2 2 0 Peroxin 13, N-terminal region DUF2722 PF10846.3 CDI85666.1 - 5.9 5.8 31.4 0.64 8.9 4.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) DUF808 PF05661.7 CDI85666.1 - 8.7 5.0 12.8 0.98 8.1 0.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF808) DUF1980 PF09323.5 CDI85666.1 - 9.7 5.8 18.1 0.55 9.9 4.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) PAT1 PF09770.4 CDI85666.1 - 10 4.2 47.9 12 3.9 33.2 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 tRNA-synt_His PF13393.1 CDI85667.1 - 3.2e-18 65.8 0.2 2.7e-10 39.8 0.0 3.3 2 1 1 3 3 3 3 Histidyl-tRNA synthetase tRNA-synt_2b PF00587.20 CDI85667.1 - 7.6e-08 32.1 0.0 1.5e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Psb28 PF03912.9 CDI85668.1 - 0.033 14.1 0.0 0.054 13.4 0.0 1.4 1 0 0 1 1 1 0 Psb28 protein Cyclin PF08613.6 CDI85669.1 - 1.1e-09 38.8 0.1 3.1e-08 34.1 0.0 2.5 2 0 0 2 2 2 1 Cyclin Hydrolase_4 PF12146.3 CDI85671.1 - 1.3e-06 28.1 0.1 0.019 14.7 0.0 2.4 2 0 0 2 2 2 2 Putative lysophospholipase Abhydrolase_6 PF12697.2 CDI85671.1 - 1.5e-06 28.2 0.8 1e-05 25.5 0.5 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CDI85671.1 - 4.9e-06 26.3 4.0 6.7e-06 25.9 1.6 2.1 2 1 0 2 2 2 1 Alpha/beta hydrolase family COPI_assoc PF08507.5 CDI85672.1 - 1.4e-11 44.2 6.9 1.8e-11 43.8 4.8 1.1 1 0 0 1 1 1 1 COPI associated protein Oxidored_q2 PF00420.19 CDI85672.1 - 3.9 7.1 8.2 4.5 6.9 0.1 2.2 2 0 0 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L Pex16 PF08610.5 CDI85675.1 - 0.17 10.8 0.1 0.17 10.8 0.1 1.8 2 0 0 2 2 2 0 Peroxisomal membrane protein (Pex16) XRN_N PF03159.13 CDI85675.1 - 0.18 11.1 4.4 0.045 13.1 0.5 1.8 1 1 1 2 2 2 0 XRN 5'-3' exonuclease N-terminus SR-25 PF10500.4 CDI85678.1 - 1.8e-07 30.8 16.3 1.9e-07 30.8 11.3 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein RskA PF10099.4 CDI85678.1 - 0.00019 21.2 2.6 0.00027 20.7 1.8 1.3 1 0 0 1 1 1 1 Anti-sigma-K factor rskA CAF-1_p150 PF11600.3 CDI85678.1 - 0.00063 19.1 19.3 0.00078 18.8 13.4 1.1 1 0 0 1 1 1 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF4175 PF13779.1 CDI85678.1 - 0.0014 16.4 26.5 0.0014 16.4 18.4 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4175) Nop53 PF07767.6 CDI85678.1 - 0.0043 16.0 16.3 0.0049 15.9 11.3 1.0 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) SAGA-Tad1 PF12767.2 CDI85678.1 - 0.018 14.6 19.7 0.022 14.4 13.6 1.0 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit TAF1D PF15333.1 CDI85678.1 - 0.023 14.4 8.7 0.029 14.1 6.0 1.1 1 0 0 1 1 1 0 TATA box-binding protein-associated factor 1D Suf PF05843.9 CDI85678.1 - 0.056 13.1 18.5 0.063 12.9 12.8 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) NARP1 PF12569.3 CDI85678.1 - 0.092 11.4 11.7 0.11 11.2 8.1 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 SprA-related PF12118.3 CDI85678.1 - 0.11 11.7 34.0 0.19 11.0 23.6 1.3 1 0 0 1 1 1 0 SprA-related family Corona_nucleoca PF00937.13 CDI85678.1 - 0.12 11.3 21.5 0.13 11.1 14.9 1.1 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein Suc_Fer-like PF06999.7 CDI85678.1 - 0.13 12.2 7.5 0.15 12.0 5.2 1.0 1 0 0 1 1 1 0 Sucrase/ferredoxin-like Herpes_TAF50 PF03326.8 CDI85678.1 - 0.15 11.0 27.0 0.17 10.7 18.7 1.0 1 0 0 1 1 1 0 Herpesvirus transcription activation factor (transactivator) DUF4603 PF15376.1 CDI85678.1 - 0.18 8.9 15.9 0.22 8.6 11.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) MRP-S31 PF15433.1 CDI85678.1 - 0.27 10.6 17.6 0.33 10.3 12.2 1.1 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 HemX PF04375.9 CDI85678.1 - 0.35 9.4 21.6 0.41 9.1 14.9 1.1 1 0 0 1 1 1 0 HemX Med15 PF09606.5 CDI85678.1 - 0.39 8.8 42.5 0.45 8.6 29.4 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF4220 PF13968.1 CDI85678.1 - 0.46 9.5 9.5 0.51 9.3 6.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4220) Transposase_21 PF02992.9 CDI85678.1 - 0.49 9.4 5.9 0.58 9.2 4.1 1.2 1 0 0 1 1 1 0 Transposase family tnp2 DUF4614 PF15391.1 CDI85678.1 - 0.57 9.9 22.5 0.75 9.5 15.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) RR_TM4-6 PF06459.7 CDI85678.1 - 0.6 9.9 12.5 0.68 9.7 8.6 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF3801 PF12687.2 CDI85678.1 - 0.69 9.4 23.3 2.6 7.5 16.1 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3801) Raftlin PF15250.1 CDI85678.1 - 0.7 8.3 18.4 0.8 8.1 12.8 1.0 1 0 0 1 1 1 0 Raftlin FLO_LFY PF01698.11 CDI85678.1 - 0.82 8.4 14.9 0.88 8.3 10.4 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein Serinc PF03348.10 CDI85678.1 - 0.85 8.2 13.4 1.1 7.8 9.3 1.3 1 0 0 1 1 1 0 Serine incorporator (Serinc) DDHD PF02862.12 CDI85678.1 - 0.85 9.3 16.6 1.1 9.0 11.5 1.2 1 0 0 1 1 1 0 DDHD domain Spc7_N PF15402.1 CDI85678.1 - 0.87 7.5 19.9 0.92 7.4 13.8 1.0 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 PBP1_TM PF14812.1 CDI85678.1 - 0.94 9.8 4.6 1.4 9.3 3.2 1.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Parvo_coat PF00740.13 CDI85678.1 - 0.94 8.3 18.7 1 8.2 13.0 1.0 1 0 0 1 1 1 0 Parvovirus coat protein VP2 DUF605 PF04652.11 CDI85678.1 - 1.1 8.6 25.8 1.2 8.4 17.9 1.1 1 0 0 1 1 1 0 Vta1 like PAT1 PF09770.4 CDI85678.1 - 1.3 7.1 31.2 1.3 7.1 21.7 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Zip PF02535.17 CDI85678.1 - 1.3 7.9 7.6 1.6 7.6 5.3 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter CDK5_activator PF03261.10 CDI85678.1 - 1.3 8.2 16.1 1.4 8.2 11.2 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein AUX_IAA PF02309.11 CDI85678.1 - 1.5 8.5 15.0 1.8 8.2 10.4 1.1 1 0 0 1 1 1 0 AUX/IAA family eIF-3_zeta PF05091.7 CDI85678.1 - 1.5 7.3 19.6 1.6 7.2 13.6 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Macoilin PF09726.4 CDI85678.1 - 1.5 6.9 17.9 2 6.5 12.4 1.2 1 0 0 1 1 1 0 Transmembrane protein DUF853 PF05872.7 CDI85678.1 - 1.6 6.9 11.8 1.7 6.9 8.2 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) DUF913 PF06025.7 CDI85678.1 - 2.2 6.9 10.8 2.5 6.7 7.5 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Dsh_C PF12316.3 CDI85678.1 - 2.6 8.1 16.9 3.1 7.8 11.7 1.2 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal CDC45 PF02724.9 CDI85678.1 - 2.8 5.8 17.2 3.2 5.6 12.0 1.0 1 0 0 1 1 1 0 CDC45-like protein Band_3_cyto PF07565.8 CDI85678.1 - 3 7.2 15.5 4 6.8 10.7 1.3 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Peptidase_S64 PF08192.6 CDI85678.1 - 3.1 6.0 19.8 3.4 5.8 13.7 1.0 1 0 0 1 1 1 0 Peptidase family S64 Apt1 PF10351.4 CDI85678.1 - 3.1 6.5 17.6 3.6 6.3 12.2 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF2201_N PF13203.1 CDI85678.1 - 3.4 6.7 19.5 4.1 6.4 13.5 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain AAA_23 PF13476.1 CDI85678.1 - 4 7.7 16.3 4.9 7.4 11.3 1.1 1 0 0 1 1 1 0 AAA domain PA26 PF04636.8 CDI85678.1 - 4.6 5.8 12.0 5.2 5.6 8.3 1.0 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) LMBR1 PF04791.11 CDI85678.1 - 5 5.6 11.0 5.5 5.4 7.6 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein Sec62 PF03839.11 CDI85678.1 - 5.1 6.4 12.0 5.9 6.2 8.3 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 DUF4544 PF15077.1 CDI85678.1 - 5.2 6.4 9.8 6.8 6.1 6.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4544) Cellulose_synt PF03552.9 CDI85678.1 - 5.5 5.1 7.7 6.2 4.9 5.3 1.0 1 0 0 1 1 1 0 Cellulose synthase Endonuc_Holl PF10107.4 CDI85678.1 - 6.9 6.3 12.6 8.8 6.0 8.7 1.2 1 0 0 1 1 1 0 Endonuclease related to archaeal Holliday junction resolvase Hid1 PF12722.2 CDI85678.1 - 7.6 4.0 19.9 8.6 3.8 13.8 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein AvrE PF11725.3 CDI85678.1 - 7.9 3.3 21.8 8.9 3.1 15.1 1.0 1 0 0 1 1 1 0 Pathogenicity factor Peptidase_S49_N PF08496.5 CDI85678.1 - 9.5 5.9 14.4 13 5.5 10.0 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal SR-25 PF10500.4 CDI85679.1 - 0.008 15.6 39.3 0.008 15.6 27.2 4.2 3 1 1 4 4 4 2 Nuclear RNA-splicing-associated protein IncA PF04156.9 CDI85680.1 - 0.00097 18.7 21.0 0.00097 18.7 14.5 10.8 4 4 3 7 7 7 1 IncA protein DUF3270 PF11674.3 CDI85680.1 - 0.0033 17.3 7.8 0.0033 17.3 5.4 8.5 8 4 2 10 10 10 1 Protein of unknown function (DUF3270) Pex14_N PF04695.8 CDI85680.1 - 0.0086 16.1 12.5 0.0086 16.1 8.7 12.9 4 3 7 11 11 11 1 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF2029 PF09594.5 CDI85680.1 - 1.7 8.0 47.8 0.013 15.0 1.9 6.6 7 0 0 7 7 7 0 Protein of unknown function (DUF2029) K_channel_TID PF07941.6 CDI85681.1 - 0.011 15.9 8.3 0.011 15.9 5.8 3.4 2 1 1 3 3 3 0 Potassium channel Kv1.4 tandem inactivation domain HSP20 PF00011.16 CDI85681.1 - 0.06 13.2 0.6 0.06 13.2 0.4 1.9 2 0 0 2 2 2 0 Hsp20/alpha crystallin family FAM176 PF14851.1 CDI85681.1 - 2.1 8.0 11.7 1.4 8.5 1.6 2.3 2 0 0 2 2 2 0 FAM176 family IL6Ra-bind PF09240.5 CDI85681.1 - 5 7.3 10.2 0.21 11.7 3.1 1.7 2 0 0 2 2 2 0 Interleukin-6 receptor alpha chain, binding Robl_LC7 PF03259.12 CDI85681.1 - 6.2 6.4 9.1 12 5.5 0.0 2.3 2 0 0 2 2 2 0 Roadblock/LC7 domain adh_short PF00106.20 CDI85682.1 - 3.9e-11 43.1 1.9 5.7e-06 26.3 0.0 4.1 3 2 1 4 4 4 2 short chain dehydrogenase NAD_binding_10 PF13460.1 CDI85682.1 - 0.0062 16.5 4.0 0.027 14.4 0.1 2.5 2 0 0 2 2 2 1 NADH(P)-binding Geminin PF07412.7 CDI85682.1 - 0.19 11.3 6.1 0.34 10.5 4.2 1.3 1 0 0 1 1 1 0 Geminin 2-Hacid_dh_C PF02826.14 CDI85682.1 - 1 8.5 5.3 3.1 6.9 0.1 2.3 1 1 1 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF2489 PF10675.4 CDI85682.1 - 6.1 6.5 19.1 4.6 6.9 1.9 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2489) DUF912 PF06024.7 CDI85684.1 - 0.0036 17.3 12.7 0.33 11.0 0.0 3.9 4 1 1 5 5 5 3 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF605 PF04652.11 CDI85684.1 - 0.0098 15.3 26.5 0.071 12.4 10.7 2.3 2 0 0 2 2 2 2 Vta1 like Tim54 PF11711.3 CDI85684.1 - 0.93 8.0 5.7 2 6.9 0.1 2.6 3 0 0 3 3 3 0 Inner membrane protein import complex subunit Tim54 AAA_23 PF13476.1 CDI85684.1 - 1.6 8.9 13.5 0.49 10.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain OmpH PF03938.9 CDI85684.1 - 6.4 6.6 36.2 0.62 9.9 5.3 3.2 3 0 0 3 3 3 0 Outer membrane protein (OmpH-like) Herpes_UL87 PF03043.9 CDI85685.1 - 8.2e-06 24.4 0.0 6.1e-05 21.6 0.0 2.0 1 1 0 1 1 1 1 Herpesvirus UL87 family Suf PF05843.9 CDI85685.1 - 0.003 17.3 3.1 0.003 17.3 2.2 2.9 2 1 0 2 2 2 1 Suppressor of forked protein (Suf) SPX PF03105.14 CDI85685.1 - 0.0038 17.0 26.0 0.056 13.2 11.9 2.2 2 0 0 2 2 2 2 SPX domain Ribosomal_L1 PF00687.16 CDI85685.1 - 0.033 13.5 0.0 0.033 13.5 0.0 2.6 3 0 0 3 3 3 0 Ribosomal protein L1p/L10e family OppC_N PF12911.2 CDI85685.1 - 0.036 13.4 0.0 0.17 11.2 0.0 2.3 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C Band_3_cyto PF07565.8 CDI85685.1 - 0.78 9.2 34.7 2 7.8 1.3 3.1 3 0 0 3 3 3 0 Band 3 cytoplasmic domain FAM60A PF15396.1 CDI85685.1 - 2.6 7.7 31.7 6.5 6.4 0.5 2.3 2 0 0 2 2 2 0 Protein Family FAM60A SAPS PF04499.10 CDI85685.1 - 2.9 6.4 30.0 3.4 6.2 0.4 2.1 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein BAF1_ABF1 PF04684.8 CDI85687.1 - 0.0037 16.1 9.0 0.0037 16.1 6.2 5.5 5 2 3 8 8 8 1 BAF1 / ABF1 chromatin reorganising factor MgtE_N PF03448.12 CDI85687.1 - 2.8 8.2 10.6 0.48 10.7 0.7 3.2 2 1 0 3 3 3 0 MgtE intracellular N domain SR-25 PF10500.4 CDI85688.1 - 0.01 15.3 8.5 0.012 15.1 5.9 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF2051 PF09738.4 CDI85688.1 - 0.014 14.7 2.8 0.015 14.6 1.9 1.0 1 0 0 1 1 1 0 Double stranded RNA binding protein (DUF2051) DUF3446 PF11928.3 CDI85688.1 - 0.2 11.9 8.1 0.23 11.6 5.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3446) Corona_nucleoca PF00937.13 CDI85688.1 - 0.33 9.8 4.2 0.34 9.8 2.9 1.0 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein BAF1_ABF1 PF04684.8 CDI85689.1 - 0.0071 15.2 11.6 0.0071 15.2 8.0 5.2 2 2 4 6 6 6 1 BAF1 / ABF1 chromatin reorganising factor AAA_23 PF13476.1 CDI85689.1 - 0.012 15.9 8.7 1.1 9.5 4.6 2.2 2 0 0 2 2 2 0 AAA domain SAGA-Tad1 PF12767.2 CDI85689.1 - 0.65 9.6 19.2 0.068 12.8 10.2 1.7 2 0 0 2 2 2 0 Transcriptional regulator of RNA polII, SAGA, subunit THRAP3_BCLAF1 PF15440.1 CDI85689.1 - 2.4 6.7 23.5 4.4 5.8 16.3 1.3 1 0 0 1 1 1 0 THRAP3/BCLAF1 family DUF726 PF05277.7 CDI85690.1 - 1.2 7.9 8.4 1.5 7.6 5.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF726) TFIIA PF03153.8 CDI85690.1 - 2.6 7.8 4.1 3.1 7.5 2.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit FRQ PF09421.5 CDI85691.1 - 0.023 12.5 0.3 0.023 12.5 0.2 2.5 2 1 1 3 3 3 0 Frequency clock protein Use1 PF09753.4 CDI85691.1 - 0.036 13.5 9.0 0.082 12.3 0.4 2.1 2 0 0 2 2 2 0 Membrane fusion protein Use1 Rtf2 PF04641.7 CDI85691.1 - 0.72 9.0 13.5 1.3 8.1 0.9 2.1 2 0 0 2 2 2 0 Rtf2 RING-finger APC_CDC26 PF10471.4 CDI85691.1 - 0.89 10.3 46.7 2.4 8.9 9.2 3.7 3 1 0 3 3 3 0 Anaphase-promoting complex APC subunit 1 ETRAMP PF09716.5 CDI85691.1 - 1.4 8.8 3.6 1.3 8.9 0.1 2.2 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) FimP PF09766.4 CDI85691.1 - 5.8 5.8 28.9 0.33 9.9 5.1 3.0 3 0 0 3 3 3 0 Fms-interacting protein BRF1 PF07741.8 CDI85691.1 - 7.5 6.8 24.0 0.57 10.4 3.0 3.0 3 0 0 3 3 3 0 Brf1-like TBP-binding domain Herpes_UL87 PF03043.9 CDI85693.1 - 0.06 11.7 6.3 0.13 10.6 1.4 1.9 1 1 1 2 2 2 0 Herpesvirus UL87 family CENP-L PF13092.1 CDI85693.1 - 0.083 12.6 0.2 0.083 12.6 0.2 2.2 2 1 0 2 2 2 0 Kinetochore complex Sim4 subunit Fta1 Spore_YhcN_YlaJ PF09580.5 CDI85693.1 - 0.14 12.2 11.2 0.11 12.6 3.1 2.3 2 0 0 2 2 2 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) Mucin PF01456.12 CDI85694.1 - 0.00027 20.7 0.7 0.00027 20.7 0.5 2.0 2 0 0 2 2 2 1 Mucin-like glycoprotein DUF1510 PF07423.6 CDI85694.1 - 0.002 17.5 5.2 0.002 17.5 3.6 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1510) HlyD_2 PF12700.2 CDI85694.1 - 0.17 11.0 11.0 0.25 10.4 7.6 1.2 1 0 0 1 1 1 0 HlyD family secretion protein AAA_23 PF13476.1 CDI85694.1 - 0.23 11.7 11.5 0.28 11.4 8.0 1.3 1 0 0 1 1 1 0 AAA domain Baculo_PP31 PF05311.6 CDI85694.1 - 0.42 9.8 7.8 0.63 9.2 5.4 1.3 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) RED_N PF07808.8 CDI85694.1 - 1.8 7.7 23.6 0.76 8.9 13.9 1.8 2 0 0 2 2 2 0 RED-like protein N-terminal region DUF4175 PF13779.1 CDI85694.1 - 1.8 6.1 44.4 0.011 13.4 25.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4175) DUF2215 PF10225.4 CDI85694.1 - 1.9 7.8 7.0 3.5 7.0 4.9 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) FPN1 PF06963.7 CDI85694.1 - 2.6 6.3 5.6 3.2 6.0 3.2 1.8 1 1 0 1 1 1 0 Ferroportin1 (FPN1) DUF4446 PF14584.1 CDI85694.1 - 6.2 6.6 7.4 32 4.3 5.1 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF4446) Nucleoporin_FG PF13634.1 CDI85696.1 - 1.9e-49 166.6 210.1 6.3e-13 48.9 35.1 5.8 1 1 4 5 5 5 5 Nucleoporin FG repeat region FimP PF09766.4 CDI85697.1 - 0.22 10.5 14.0 0.23 10.5 9.7 1.0 1 0 0 1 1 1 0 Fms-interacting protein DUF3408 PF11888.3 CDI85697.1 - 0.44 10.4 5.7 0.49 10.3 3.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) BRF1 PF07741.8 CDI85697.1 - 0.47 10.7 6.7 0.63 10.3 4.6 1.2 1 0 0 1 1 1 0 Brf1-like TBP-binding domain GvpL_GvpF PF06386.6 CDI85697.1 - 0.5 9.8 7.2 0.59 9.6 5.0 1.1 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF DUF4557 PF15101.1 CDI85697.1 - 0.72 9.6 11.7 0.74 9.6 8.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) Band_3_cyto PF07565.8 CDI85697.1 - 0.91 8.9 4.5 0.87 9.0 3.1 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Peptidase_S49_N PF08496.5 CDI85697.1 - 1.3 8.8 4.2 1.4 8.6 2.9 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Pex14_N PF04695.8 CDI85697.1 - 2 8.4 10.7 2 8.4 7.4 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Suf PF05843.9 CDI85697.1 - 2.1 7.9 10.9 2.1 8.0 7.5 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) PAT1 PF09770.4 CDI85697.1 - 2.6 6.1 22.9 2.8 6.0 15.9 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 ATHILA PF03078.10 CDI85697.1 - 3.5 6.0 5.9 3.6 6.0 4.1 1.0 1 0 0 1 1 1 0 ATHILA ORF-1 family DUF4407 PF14362.1 CDI85697.1 - 3.9 6.3 6.7 3.9 6.3 4.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Serinc PF03348.10 CDI85697.1 - 5.2 5.6 5.0 5.4 5.6 3.5 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) ERF PF04404.7 CDI85697.1 - 5.3 6.5 13.8 6.2 6.3 9.6 1.2 1 0 0 1 1 1 0 ERF superfamily DUF4094 PF13334.1 CDI85697.1 - 6 7.3 10.0 8.9 6.7 6.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4094) Med15 PF09606.5 CDI85697.1 - 6.7 4.7 26.7 6.8 4.7 18.5 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Sec20 PF03908.8 CDI85698.1 - 0.0014 18.3 2.7 0.0014 18.3 1.9 2.7 2 1 2 4 4 4 1 Sec20 Ycf1 PF05758.7 CDI85699.1 - 0.0089 13.8 0.1 0.0089 13.8 0.1 2.2 2 1 0 2 2 2 1 Ycf1 RAP1 PF07218.6 CDI85699.1 - 2 6.3 3.7 4 5.4 2.6 1.4 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Med15 PF09606.5 CDI85699.1 - 9.1 4.3 76.8 0.083 11.0 43.1 2.5 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal Thioredoxin PF00085.15 CDI85701.1 - 1.8e-38 130.3 0.0 5.7e-21 74.1 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_6 PF13848.1 CDI85701.1 - 2e-11 44.0 0.0 2.7e-06 27.3 0.0 3.7 3 1 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_2 PF13098.1 CDI85701.1 - 3.8e-07 30.2 0.0 0.0053 16.9 0.0 3.5 2 1 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_8 PF13905.1 CDI85701.1 - 2.9e-05 24.1 0.0 0.39 10.8 0.0 2.8 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_7 PF13899.1 CDI85701.1 - 0.0055 16.6 0.9 0.95 9.5 0.0 3.5 4 0 0 4 4 4 1 Thioredoxin-like AhpC-TSA PF00578.16 CDI85701.1 - 0.016 14.8 0.0 3.3 7.4 0.0 2.7 2 0 0 2 2 2 0 AhpC/TSA family Redoxin PF08534.5 CDI85701.1 - 0.052 13.0 0.1 0.9 9.0 0.0 2.6 3 0 0 3 3 3 0 Redoxin RCC1 PF00415.13 CDI85702.1 - 1.2e-60 201.4 44.2 1.3e-14 54.1 0.8 8.3 7 1 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 CDI85702.1 - 3.1e-40 134.9 49.4 3.7e-09 35.9 0.8 8.5 8 0 0 8 8 8 7 Regulator of chromosome condensation (RCC1) repeat Hira PF07569.6 CDI85702.1 - 0.00029 20.1 0.4 0.55 9.4 0.0 3.9 4 0 0 4 4 4 2 TUP1-like enhancer of split CBM_X PF06204.6 CDI85702.1 - 0.0014 18.0 0.2 2.6 7.6 0.0 3.7 4 0 0 4 4 4 2 Putative carbohydrate binding domain Kelch_2 PF07646.10 CDI85702.1 - 0.0032 17.1 6.4 19 5.2 0.1 5.8 7 0 0 7 7 7 1 Kelch motif Tfb4 PF03850.9 CDI85703.1 - 6.2 5.9 18.6 7.5 5.7 12.9 1.1 1 0 0 1 1 1 0 Transcription factor Tfb4 Ribosomal_60s PF00428.14 CDI85705.1 - 0.019 15.3 24.3 0.074 13.4 8.4 2.7 2 0 0 2 2 2 0 60s Acidic ribosomal protein DUF3487 PF11990.3 CDI85705.1 - 0.83 9.0 3.4 1.9 7.9 2.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3487) RAP1 PF07218.6 CDI85705.1 - 0.9 7.5 6.0 0.87 7.6 3.6 1.3 1 1 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Macoilin PF09726.4 CDI85705.1 - 3.8 5.6 40.8 6.2 4.9 28.3 1.3 1 0 0 1 1 1 0 Transmembrane protein DUF3292 PF11696.3 CDI85706.1 - 1.4 6.6 7.3 1.5 6.5 5.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) DUF1764 PF08576.5 CDI85706.1 - 1.6 9.5 13.4 1.7 9.4 9.3 1.3 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) Pal1 PF08316.6 CDI85706.1 - 2.3 8.6 8.1 2.5 8.5 5.6 1.0 1 0 0 1 1 1 0 Pal1 cell morphology protein DUF4175 PF13779.1 CDI85706.1 - 3.1 5.3 35.7 2.8 5.5 24.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Peptidase_U57 PF05582.7 CDI85706.1 - 4.3 6.2 10.8 4.6 6.1 7.5 1.0 1 0 0 1 1 1 0 YabG peptidase U57 Spore_coat_CotO PF14153.1 CDI85706.1 - 4.4 6.6 19.3 4.3 6.7 13.4 1.1 1 0 0 1 1 1 0 Spore coat protein CotO SprA-related PF12118.3 CDI85706.1 - 4.8 6.4 34.0 4.8 6.4 23.6 1.0 1 0 0 1 1 1 0 SprA-related family RR_TM4-6 PF06459.7 CDI85706.1 - 4.8 6.9 15.1 4.7 7.0 10.5 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CRF1 PF10380.4 CDI85706.1 - 5.8 7.2 10.5 6.9 7.0 7.3 1.1 1 0 0 1 1 1 0 Transcription factor CRF1 Band_3_cyto PF07565.8 CDI85706.1 - 6.1 6.2 16.9 6.5 6.1 11.7 1.0 1 0 0 1 1 1 0 Band 3 cytoplasmic domain DUF4512 PF14975.1 CDI85706.1 - 7.1 7.5 7.8 8.5 7.2 5.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4512) Peptidase_S49_N PF08496.5 CDI85706.1 - 7.4 6.3 12.2 7.8 6.2 8.5 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Med15 PF09606.5 CDI85706.1 - 7.6 4.5 44.0 7.2 4.6 30.5 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Gti1_Pac2 PF09729.4 CDI85706.1 - 7.6 6.3 9.2 7.7 6.3 6.4 1.1 1 0 0 1 1 1 0 Gti1/Pac2 family AAA_23 PF13476.1 CDI85706.1 - 7.7 6.7 13.5 8 6.7 9.4 1.1 1 0 0 1 1 1 0 AAA domain Paf1 PF03985.8 CDI85706.1 - 9.3 4.8 17.6 9.1 4.8 12.2 1.0 1 0 0 1 1 1 0 Paf1 DUF3381 PF11861.3 CDI85706.1 - 9.4 5.7 13.2 9.4 5.7 9.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) AIF_C PF14721.1 CDI85706.1 - 9.5 6.4 12.5 11 6.3 8.7 1.1 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term DUF3597 PF12200.3 CDI85708.1 - 0.008 16.5 4.6 0.008 16.5 3.2 4.6 5 1 0 5 5 5 1 Domain of unknown function (DUF3597) SID-1_RNA_chan PF13965.1 CDI85708.1 - 1.5 6.9 11.3 1.7 6.7 4.7 2.2 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 N6_N4_Mtase PF01555.13 CDI85709.1 - 0.036 13.5 0.0 0.055 12.9 0.0 1.3 1 1 0 1 1 1 0 DNA methylase Adap_comp_sub PF00928.16 CDI85709.1 - 0.14 11.2 2.6 0.15 11.1 1.8 1.1 1 0 0 1 1 1 0 Adaptor complexes medium subunit family 7TM_GPCR_Srv PF10323.4 CDI85710.1 - 0.011 14.9 4.3 0.37 9.8 0.0 2.2 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srv Arteri_nucleo PF01481.11 CDI85710.1 - 0.023 14.7 8.9 0.039 14.0 6.2 1.5 1 0 0 1 1 1 0 Arterivirus nucleocapsid protein NST1 PF13945.1 CDI85710.1 - 0.42 10.6 10.6 0.39 10.7 5.3 1.9 2 0 0 2 2 2 0 Salt tolerance down-regulator CECR6_TMEM121 PF14997.1 CDI85710.1 - 0.53 9.8 4.2 1.9 8.0 0.2 2.2 1 1 0 2 2 2 0 CECR6/TMEM121 family Protocadherin PF08374.6 CDI85710.1 - 0.53 9.8 5.8 0.04 13.5 0.8 1.4 2 0 0 2 2 2 0 Protocadherin PBP1_TM PF14812.1 CDI85710.1 - 0.54 10.6 4.2 62 3.9 2.4 2.9 2 1 1 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Corona_nucleoca PF00937.13 CDI85710.1 - 1.6 7.6 7.0 2.6 6.9 4.9 1.3 1 1 0 1 1 1 0 Coronavirus nucleocapsid protein Activator_LAG-3 PF11498.3 CDI85710.1 - 2.9 6.5 18.1 3.7 6.2 12.6 1.4 1 0 0 1 1 1 0 Transcriptional activator LAG-3 DUF912 PF06024.7 CDI85710.1 - 4.4 7.4 6.6 19 5.3 0.0 2.8 2 1 1 3 3 3 0 Nucleopolyhedrovirus protein of unknown function (DUF912) AAA_23 PF13476.1 CDI85710.1 - 8.2 6.6 12.5 11 6.2 8.6 1.3 1 0 0 1 1 1 0 AAA domain PAT1 PF09770.4 CDI85711.1 - 0.0028 15.9 73.9 0.0035 15.6 51.2 1.1 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 RAP1 PF07218.6 CDI85711.1 - 0.031 12.4 29.5 0.061 11.4 0.9 2.1 2 0 0 2 2 2 0 Rhoptry-associated protein 1 (RAP-1) Med15 PF09606.5 CDI85711.1 - 3.2 5.8 120.6 0.98 7.5 63.1 2.0 1 1 1 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF2217 PF10265.4 CDI85711.1 - 4.6 5.8 42.3 1.9 7.1 9.9 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2217) FimP PF09766.4 CDI85712.1 - 0.0036 16.4 3.5 0.0036 16.4 2.4 2.2 2 0 0 2 2 2 1 Fms-interacting protein AUX_IAA PF02309.11 CDI85712.1 - 0.041 13.6 11.5 0.12 12.1 1.2 2.1 2 0 0 2 2 2 0 AUX/IAA family FCP1_C PF09309.5 CDI85712.1 - 0.064 12.5 20.3 0.31 10.3 4.0 2.3 2 0 0 2 2 2 0 FCP1, C-terminal 7TM_GPCR_Str PF10326.4 CDI85712.1 - 0.1 11.7 6.8 0.15 11.1 4.7 1.2 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Str Serinc PF03348.10 CDI85712.1 - 0.15 10.7 11.7 0.54 8.9 3.7 2.2 2 1 0 2 2 2 0 Serine incorporator (Serinc) RR_TM4-6 PF06459.7 CDI85712.1 - 0.16 11.8 10.7 0.93 9.3 1.1 2.1 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Neur_chan_memb PF02932.11 CDI85712.1 - 0.19 11.6 9.6 0.26 11.1 0.2 2.1 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Herpes_env PF01673.13 CDI85712.1 - 0.35 9.3 6.4 1.5 7.3 1.0 2.0 2 0 0 2 2 2 0 Herpesvirus putative major envelope glycoprotein AAA_23 PF13476.1 CDI85712.1 - 0.5 10.6 19.2 1.7 8.9 4.2 2.3 2 0 0 2 2 2 0 AAA domain DUF808 PF05661.7 CDI85712.1 - 0.56 8.9 4.2 5.3 5.7 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF808) OAD_gamma PF04277.8 CDI85712.1 - 0.56 10.6 4.6 8.4 6.8 0.5 2.6 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain Peptidase_U57 PF05582.7 CDI85712.1 - 0.58 9.0 11.4 0.12 11.3 0.9 2.1 2 0 0 2 2 2 0 YabG peptidase U57 AIF_C PF14721.1 CDI85712.1 - 0.6 10.3 9.0 1.3 9.3 0.5 2.2 2 0 0 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Plasmodium_Vir PF05795.6 CDI85712.1 - 0.62 9.2 7.8 0.093 11.9 0.6 2.0 2 0 0 2 2 2 0 Plasmodium vivax Vir protein TMEM247 PF15444.1 CDI85712.1 - 0.7 9.6 14.1 1.1 8.9 1.9 2.2 2 0 0 2 2 2 0 Transmembrane protein 247 Med15 PF09606.5 CDI85712.1 - 0.91 7.6 52.4 0.39 8.8 11.9 2.2 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal Band_3_cyto PF07565.8 CDI85712.1 - 1 8.8 17.7 0.5 9.8 1.1 2.1 2 0 0 2 2 2 0 Band 3 cytoplasmic domain DRY_EERY PF09750.4 CDI85712.1 - 1.1 9.3 12.7 0.93 9.6 1.7 2.3 2 0 0 2 2 2 0 Alternative splicing regulator Ctr PF04145.10 CDI85712.1 - 1.2 9.1 7.5 0.88 9.6 0.6 2.3 2 0 0 2 2 2 0 Ctr copper transporter family DUF2763 PF10961.3 CDI85712.1 - 1.9 8.9 0.0 1.9 8.9 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2763) RED_N PF07808.8 CDI85712.1 - 2.3 7.3 24.9 0.92 8.6 5.0 2.3 2 0 0 2 2 2 0 RED-like protein N-terminal region ARD PF03079.9 CDI85712.1 - 2.4 8.0 10.1 0.31 10.9 1.6 2.1 2 0 0 2 2 2 0 ARD/ARD' family BORG_CEP PF14957.1 CDI85712.1 - 3.4 8.6 9.7 1.8 9.5 1.6 2.3 2 0 0 2 2 2 0 Cdc42 effector DUF853 PF05872.7 CDI85712.1 - 3.7 5.7 13.4 0.63 8.3 2.0 2.1 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF853) DUF3306 PF11748.3 CDI85712.1 - 4.4 7.9 16.8 6.2 7.5 2.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3306) DUF3408 PF11888.3 CDI85712.1 - 6.4 6.7 16.9 6.4 6.7 1.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3408) Nitroreductase PF00881.19 CDI85712.1 - 6.7 6.5 7.9 7.1 6.4 0.4 2.2 2 0 0 2 2 2 0 Nitroreductase family Folliculin PF11704.3 CDI85712.1 - 6.9 6.2 12.3 5.7 6.4 2.4 2.2 2 0 0 2 2 2 0 Vesicle coat protein involved in Golgi to plasma membrane transport DUF4414 PF14377.1 CDI85712.1 - 8 6.4 24.8 1.1 9.1 3.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4414) PCYCGC PF13798.1 CDI85712.1 - 8.6 6.0 9.8 2.6 7.7 2.3 2.2 2 0 0 2 2 2 0 Protein of unknown function with PCYCGC motif DUF4483 PF14825.1 CDI85712.1 - 9.3 5.8 17.2 1.3 8.6 3.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4483) TraV PF09676.5 CDI85712.1 - 9.5 6.9 12.2 9 7.0 2.0 2.5 2 0 0 2 2 2 0 Type IV conjugative transfer system lipoprotein (TraV) ATAD4 PF15321.1 CDI85712.1 - 9.7 7.2 16.1 13 6.8 1.4 2.3 2 0 0 2 2 2 0 ATPase family AAA domain containing 4 Ribosomal_60s PF00428.14 CDI85714.1 - 0.00067 20.0 12.7 0.00067 20.0 8.8 3.3 2 1 1 3 3 3 1 60s Acidic ribosomal protein Daxx PF03344.10 CDI85714.1 - 0.14 10.5 52.0 0.019 13.4 25.0 2.0 2 0 0 2 2 2 0 Daxx Family Shadoo PF14999.1 CDI85714.1 - 0.18 11.6 14.9 0.18 11.6 5.0 2.3 2 0 0 2 2 2 0 Shadow of prion protein, neuroprotective Med15 PF09606.5 CDI85714.1 - 2.3 6.3 37.5 0.023 12.9 4.1 2.1 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal Herpes_DNAp_acc PF04929.7 CDI85714.1 - 3.7 6.4 23.4 0.19 10.6 8.4 2.2 1 1 1 2 2 2 0 Herpes DNA replication accessory factor DUF1510 PF07423.6 CDI85715.1 - 0.00036 19.9 15.2 0.00039 19.8 10.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) DUF3987 PF13148.1 CDI85715.1 - 0.0014 17.2 9.5 0.0017 17.0 6.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3987) FimP PF09766.4 CDI85715.1 - 0.0037 16.4 25.0 0.0057 15.7 17.4 1.3 1 0 0 1 1 1 1 Fms-interacting protein Spore_coat_CotO PF14153.1 CDI85715.1 - 0.01 15.2 24.3 0.012 15.1 16.9 1.1 1 0 0 1 1 1 0 Spore coat protein CotO TRAP_alpha PF03896.11 CDI85715.1 - 0.017 14.1 5.3 0.018 14.0 3.7 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit AAA_11 PF13086.1 CDI85715.1 - 0.024 14.2 15.8 0.028 13.9 10.9 1.0 1 0 0 1 1 1 0 AAA domain NARP1 PF12569.3 CDI85715.1 - 0.026 13.2 14.7 0.027 13.2 10.2 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 YfhO PF09586.5 CDI85715.1 - 0.036 12.0 7.1 0.037 12.0 4.9 1.0 1 0 0 1 1 1 0 Bacterial membrane protein YfhO AUX_IAA PF02309.11 CDI85715.1 - 0.047 13.4 9.1 0.047 13.4 6.3 1.1 1 0 0 1 1 1 0 AUX/IAA family Raftlin PF15250.1 CDI85715.1 - 0.055 11.9 12.6 0.055 11.9 8.7 1.0 1 0 0 1 1 1 0 Raftlin Ycf1 PF05758.7 CDI85715.1 - 0.055 11.1 16.8 0.054 11.2 11.6 1.0 1 0 0 1 1 1 0 Ycf1 DUF3408 PF11888.3 CDI85715.1 - 0.057 13.3 15.0 0.072 13.0 10.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) Baculo_PP31 PF05311.6 CDI85715.1 - 0.077 12.2 11.7 0.082 12.1 8.1 1.1 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) YqfQ PF14181.1 CDI85715.1 - 0.093 12.7 20.3 0.12 12.4 14.1 1.1 1 0 0 1 1 1 0 YqfQ-like protein DUF3260 PF11658.3 CDI85715.1 - 0.095 10.8 12.3 0.1 10.7 8.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3260) Hid1 PF12722.2 CDI85715.1 - 0.11 10.2 14.8 0.11 10.1 10.2 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein FYDLN_acid PF09538.5 CDI85715.1 - 0.11 13.0 9.8 0.15 12.6 6.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) CDC45 PF02724.9 CDI85715.1 - 0.11 10.4 15.0 0.12 10.3 10.4 1.0 1 0 0 1 1 1 0 CDC45-like protein RIC3 PF15361.1 CDI85715.1 - 0.12 12.6 11.8 0.15 12.2 8.2 1.2 1 0 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 GAGA_bind PF06217.7 CDI85715.1 - 0.13 12.2 11.8 0.13 12.1 8.2 1.0 1 0 0 1 1 1 0 GAGA binding protein-like family Band_3_cyto PF07565.8 CDI85715.1 - 0.13 11.7 15.7 0.15 11.5 10.9 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Folate_carrier PF01770.13 CDI85715.1 - 0.14 10.6 8.8 0.16 10.4 6.1 1.2 1 0 0 1 1 1 0 Reduced folate carrier DUF2052 PF09747.4 CDI85715.1 - 0.15 12.0 24.2 0.17 11.8 16.8 1.1 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) RP-C_C PF11800.3 CDI85715.1 - 0.15 11.7 12.4 0.16 11.6 8.6 1.1 1 0 0 1 1 1 0 Replication protein C C-terminal region DUF4512 PF14975.1 CDI85715.1 - 0.2 12.5 10.4 0.25 12.2 7.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4512) Peptidase_S49_N PF08496.5 CDI85715.1 - 0.2 11.4 14.3 0.24 11.1 9.9 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Zip PF02535.17 CDI85715.1 - 0.21 10.5 4.8 0.21 10.5 3.3 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter RR_TM4-6 PF06459.7 CDI85715.1 - 0.21 11.4 20.0 0.23 11.3 13.9 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Mem_trans PF03547.13 CDI85715.1 - 0.22 9.8 7.9 0.22 9.7 5.5 1.1 1 0 0 1 1 1 0 Membrane transport protein Hom_end_hint PF05203.11 CDI85715.1 - 0.22 11.2 10.3 0.25 11.0 7.1 1.1 1 0 0 1 1 1 0 Hom_end-associated Hint DUF3449 PF11931.3 CDI85715.1 - 0.24 10.8 17.1 0.3 10.5 11.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3449) Tim54 PF11711.3 CDI85715.1 - 0.24 9.9 12.9 0.25 9.8 8.9 1.0 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Herpes_DNAp_acc PF04929.7 CDI85715.1 - 0.24 10.3 12.7 0.25 10.2 8.8 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor PAT1 PF09770.4 CDI85715.1 - 0.25 9.5 37.0 0.27 9.4 25.6 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF1266 PF06889.6 CDI85715.1 - 0.25 11.1 9.3 0.32 10.7 6.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1266) DUF913 PF06025.7 CDI85715.1 - 0.25 10.0 9.2 0.25 10.0 6.4 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) BORG_CEP PF14957.1 CDI85715.1 - 0.31 11.9 10.5 0.41 11.5 7.3 1.2 1 0 0 1 1 1 0 Cdc42 effector Serinc PF03348.10 CDI85715.1 - 0.32 9.6 14.1 0.36 9.4 9.8 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) DUF4045 PF13254.1 CDI85715.1 - 0.32 10.2 14.6 0.36 10.0 10.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) DUF2370 PF10176.4 CDI85715.1 - 0.33 10.2 6.5 0.34 10.1 4.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) SID-1_RNA_chan PF13965.1 CDI85715.1 - 0.35 8.9 7.6 0.33 9.0 5.3 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DDHD PF02862.12 CDI85715.1 - 0.36 10.5 16.9 0.4 10.4 11.7 1.1 1 0 0 1 1 1 0 DDHD domain Bul1_N PF04425.7 CDI85715.1 - 0.41 9.1 12.3 0.42 9.1 8.5 1.0 1 0 0 1 1 1 0 Bul1 N terminus LAG1-DNAbind PF09271.6 CDI85715.1 - 0.41 11.1 12.2 0.52 10.7 8.5 1.1 1 0 0 1 1 1 0 LAG1, DNA binding DUF2201_N PF13203.1 CDI85715.1 - 0.43 9.7 15.3 0.49 9.5 10.6 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain ABC2_membrane_2 PF12679.2 CDI85715.1 - 0.47 9.2 1.9 0.55 9.0 1.3 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF1448 PF07289.6 CDI85715.1 - 0.47 9.3 12.3 0.55 9.0 8.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1448) FAM60A PF15396.1 CDI85715.1 - 0.5 10.0 11.0 0.57 9.8 7.6 1.1 1 0 0 1 1 1 0 Protein Family FAM60A Gti1_Pac2 PF09729.4 CDI85715.1 - 0.51 10.1 11.5 0.6 9.9 8.0 1.1 1 0 0 1 1 1 0 Gti1/Pac2 family SAPS PF04499.10 CDI85715.1 - 0.53 8.8 14.5 0.61 8.6 10.0 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Pex14_N PF04695.8 CDI85715.1 - 0.53 10.3 21.0 0.65 10.0 14.6 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region TFIIA PF03153.8 CDI85715.1 - 0.55 10.0 27.6 0.59 9.9 19.1 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Peptidase_U57 PF05582.7 CDI85715.1 - 0.56 9.1 12.2 0.6 9.0 8.5 1.1 1 0 0 1 1 1 0 YabG peptidase U57 Dynamin_N PF00350.18 CDI85715.1 - 0.56 10.0 10.9 0.57 9.9 7.5 1.1 1 0 0 1 1 1 0 Dynamin family RNA_pol_Rpb1_5 PF04998.12 CDI85715.1 - 0.58 9.3 10.1 0.61 9.2 7.0 1.0 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 Pox_Ag35 PF03286.9 CDI85715.1 - 0.64 9.5 13.4 0.72 9.3 9.3 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein HSP90 PF00183.13 CDI85715.1 - 0.64 8.3 11.4 0.75 8.1 7.9 1.0 1 0 0 1 1 1 0 Hsp90 protein DUF3381 PF11861.3 CDI85715.1 - 0.65 9.4 22.2 0.79 9.2 15.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) DUF2561 PF10812.3 CDI85715.1 - 0.76 9.3 3.6 0.9 9.1 2.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2561) Astro_capsid PF03115.9 CDI85715.1 - 0.77 7.9 8.8 0.85 7.8 6.1 1.1 1 0 0 1 1 1 0 Astrovirus capsid protein precursor SpoIIP PF07454.6 CDI85715.1 - 0.78 8.8 14.6 0.86 8.7 10.1 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Neur_chan_memb PF02932.11 CDI85715.1 - 0.82 9.4 9.6 0.88 9.4 6.6 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DDRGK PF09756.4 CDI85715.1 - 0.89 8.9 33.2 1.2 8.5 23.0 1.1 1 0 0 1 1 1 0 DDRGK domain F-protein PF00469.15 CDI85715.1 - 0.9 8.8 16.8 1 8.7 11.6 1.1 1 0 0 1 1 1 0 Negative factor, (F-Protein) or Nef AIF_C PF14721.1 CDI85715.1 - 0.98 9.6 17.1 1.3 9.2 11.9 1.1 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term FAM91_C PF14648.1 CDI85715.1 - 1 8.1 8.3 1.1 8.0 5.7 1.0 1 0 0 1 1 1 0 FAM91 C-terminus FLO_LFY PF01698.11 CDI85715.1 - 1.1 7.9 16.9 1.3 7.8 11.7 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein Pox_P4B PF03292.9 CDI85715.1 - 1.3 6.9 6.5 1.3 6.8 4.5 1.0 1 0 0 1 1 1 0 Poxvirus P4B major core protein HGTP_anticodon2 PF12745.2 CDI85715.1 - 1.3 8.1 17.4 1.6 7.7 12.1 1.1 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs CRF1 PF10380.4 CDI85715.1 - 1.6 9.0 10.2 1.9 8.8 7.0 1.4 1 0 0 1 1 1 0 Transcription factor CRF1 PPP4R2 PF09184.6 CDI85715.1 - 1.6 8.1 19.3 1.9 7.9 13.4 1.1 1 0 0 1 1 1 0 PPP4R2 TT_ORF1 PF02956.9 CDI85715.1 - 1.7 7.0 14.7 1.8 6.9 10.2 1.0 1 0 0 1 1 1 0 TT viral orf 1 DUF2828 PF11443.3 CDI85715.1 - 1.8 6.6 13.5 2.1 6.4 9.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) CPSF100_C PF13299.1 CDI85715.1 - 2 8.5 15.2 2.4 8.3 10.5 1.1 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal GPCR_chapero_1 PF11904.3 CDI85715.1 - 2.3 7.2 15.1 2.5 7.1 10.5 1.1 1 0 0 1 1 1 0 GPCR-chaperone Pal1 PF08316.6 CDI85715.1 - 2.3 8.6 7.9 2.7 8.4 5.4 1.1 1 0 0 1 1 1 0 Pal1 cell morphology protein DUF2215 PF10225.4 CDI85715.1 - 2.5 7.5 11.0 3 7.2 7.6 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) YABBY PF04690.8 CDI85715.1 - 2.6 8.2 11.0 2.9 8.0 7.6 1.1 1 0 0 1 1 1 0 YABBY protein DUF4220 PF13968.1 CDI85715.1 - 2.6 7.0 8.8 2.6 7.0 6.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4220) FNIP_N PF14636.1 CDI85715.1 - 2.7 8.4 15.3 3.2 8.2 10.6 1.1 1 0 0 1 1 1 0 Folliculin-interacting protein N-terminus PCEMA1 PF07418.6 CDI85715.1 - 2.8 7.2 12.6 3.2 7.0 8.7 1.1 1 0 0 1 1 1 0 Acidic phosphoprotein precursor PCEMA1 UPF0565 PF10561.4 CDI85715.1 - 2.8 6.7 13.5 3.2 6.5 9.4 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0565 Presenilin PF01080.12 CDI85715.1 - 3.1 6.5 12.1 3.5 6.3 8.4 1.1 1 0 0 1 1 1 0 Presenilin Cellulose_synt PF03552.9 CDI85715.1 - 3.1 5.9 8.3 3.1 5.9 5.8 1.0 1 0 0 1 1 1 0 Cellulose synthase Paramyxo_ncap PF00973.14 CDI85715.1 - 3.2 6.3 13.6 3.5 6.2 9.4 1.0 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein DUF2126 PF09899.4 CDI85715.1 - 3.6 5.4 14.2 3.8 5.4 9.9 1.0 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) HCO3_cotransp PF00955.16 CDI85715.1 - 3.8 6.0 5.6 3.8 6.0 3.9 1.0 1 0 0 1 1 1 0 HCO3- transporter family CRT10 PF08728.5 CDI85715.1 - 4.1 5.2 11.5 4.2 5.2 8.0 1.0 1 0 0 1 1 1 0 CRT10 Glyco_transf_15 PF01793.11 CDI85715.1 - 4.5 6.1 18.7 5.7 5.7 13.0 1.1 1 0 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase Pap_E4 PF02711.9 CDI85715.1 - 4.6 8.1 20.8 5.7 7.8 14.3 1.3 1 1 0 1 1 1 0 E4 protein Kei1 PF08552.6 CDI85715.1 - 4.7 6.8 14.7 6.5 6.3 10.2 1.2 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 DUF2946 PF11162.3 CDI85715.1 - 4.7 7.4 8.1 7 6.8 5.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2946) SeqA PF03925.8 CDI85715.1 - 4.8 6.8 16.9 6.3 6.4 11.7 1.1 1 0 0 1 1 1 0 SeqA protein HSP70 PF00012.15 CDI85715.1 - 4.8 4.9 14.0 5.2 4.8 9.7 1.0 1 0 0 1 1 1 0 Hsp70 protein DUF2058 PF09831.4 CDI85715.1 - 5.8 6.7 31.2 7.3 6.4 21.6 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2058) AMP-binding PF00501.23 CDI85715.1 - 6.4 5.0 5.6 7.3 4.8 3.8 1.0 1 0 0 1 1 1 0 AMP-binding enzyme Peptidase_S15 PF02129.13 CDI85715.1 - 6.6 6.0 14.4 7.5 5.8 10.0 1.1 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Bud13 PF09736.4 CDI85715.1 - 6.6 6.9 28.7 8.9 6.5 19.9 1.1 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex DUF1800 PF08811.6 CDI85715.1 - 6.9 5.4 19.3 7.3 5.3 13.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1800) DUF1003 PF06210.6 CDI85715.1 - 7.1 6.6 16.4 8.6 6.3 11.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1003) Asp-B-Hydro_N PF05279.6 CDI85715.1 - 7.4 6.3 19.6 9.3 6.0 13.6 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Med15 PF09606.5 CDI85715.1 - 7.8 4.5 53.4 8.2 4.4 37.0 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Anoctamin PF04547.7 CDI85715.1 - 7.9 5.0 12.8 8.3 4.9 8.9 1.1 1 0 0 1 1 1 0 Calcium-activated chloride channel OATP PF03137.15 CDI85715.1 - 8.6 4.2 14.4 9.6 4.1 10.0 1.2 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Spore_YhcN_YlaJ PF09580.5 CDI85715.1 - 9.3 6.3 18.2 12 5.9 12.6 1.1 1 0 0 1 1 1 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) XRN_N PF03159.13 CDI85715.1 - 9.4 5.5 12.7 13 5.1 8.8 1.2 1 0 0 1 1 1 0 XRN 5'-3' exonuclease N-terminus CDC45 PF02724.9 CDI85718.1 - 0.0069 14.4 24.7 0.0088 14.1 17.1 1.1 1 0 0 1 1 1 1 CDC45-like protein Ycf1 PF05758.7 CDI85718.1 - 0.013 13.2 21.9 0.016 12.9 15.2 1.2 1 0 0 1 1 1 0 Ycf1 SPX PF03105.14 CDI85718.1 - 0.24 11.1 24.1 0.33 10.6 16.7 1.3 1 0 0 1 1 1 0 SPX domain CRT10 PF08728.5 CDI85718.1 - 1.1 7.1 11.7 1.2 7.0 8.1 1.1 1 0 0 1 1 1 0 CRT10 Cyto_heme_lyase PF01265.12 CDI85718.1 - 1.3 8.5 21.5 0.32 10.5 12.2 1.9 2 0 0 2 2 2 0 Cytochrome c/c1 heme lyase Dicty_REP PF05086.7 CDI85718.1 - 1.4 6.5 17.4 1.7 6.3 12.0 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Otopetrin PF03189.8 CDI85718.1 - 1.6 7.6 6.7 2.1 7.2 4.7 1.3 1 0 0 1 1 1 0 Otopetrin AUX_IAA PF02309.11 CDI85718.1 - 2.2 7.9 28.7 0.069 12.8 15.0 2.0 2 0 0 2 2 2 0 AUX/IAA family MIP-T3 PF10243.4 CDI85718.1 - 2.5 6.4 51.2 1.3 7.3 34.1 1.5 1 1 0 1 1 1 0 Microtubule-binding protein MIP-T3 Presenilin PF01080.12 CDI85718.1 - 3 6.5 20.1 4.5 5.9 13.9 1.3 1 0 0 1 1 1 0 Presenilin LMBR1 PF04791.11 CDI85718.1 - 3.2 6.2 9.8 3.3 6.1 6.8 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein SAGA-Tad1 PF12767.2 CDI85718.1 - 4 7.0 35.5 0.078 12.6 18.0 2.1 2 0 0 2 2 2 0 Transcriptional regulator of RNA polII, SAGA, subunit PAT1 PF09770.4 CDI85718.1 - 4.4 5.4 70.7 5.2 5.1 49.0 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Med5 PF08689.5 CDI85718.1 - 9 3.8 24.1 12 3.3 16.7 1.2 1 0 0 1 1 1 0 Mediator complex subunit Med5 CaATP_NAI PF12515.3 CDI85720.1 - 0.00067 19.1 0.2 0.0015 17.9 0.1 1.5 1 0 0 1 1 1 1 Ca2+-ATPase N terminal autoinhibitory domain Pacs-1 PF10254.4 CDI85721.1 - 0.35 9.4 0.0 0.35 9.4 0.0 2.1 2 0 0 2 2 2 0 PACS-1 cytosolic sorting protein Macoilin PF09726.4 CDI85721.1 - 4.1 5.5 16.1 0.74 8.0 8.8 1.5 2 0 0 2 2 2 0 Transmembrane protein DUF1675 PF07897.6 CDI85722.1 - 0.88 9.3 42.9 1.1 9.0 29.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) Abhydrolase_5 PF12695.2 CDI85723.1 - 2.6e-25 88.8 0.0 4.1e-25 88.2 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CDI85723.1 - 6.6e-19 68.6 0.2 1.1e-17 64.6 0.2 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CDI85723.1 - 3.7e-13 49.5 0.0 1e-08 35.0 0.0 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold AXE1 PF05448.7 CDI85723.1 - 1.8e-08 33.2 0.1 0.0035 15.8 0.1 2.3 1 1 1 2 2 2 2 Acetyl xylan esterase (AXE1) DLH PF01738.13 CDI85723.1 - 3.4e-06 26.4 0.0 1.4e-05 24.4 0.0 1.8 1 1 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S9 PF00326.16 CDI85723.1 - 0.00024 20.3 0.0 0.00041 19.6 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.13 CDI85723.1 - 0.0018 17.7 0.0 0.0057 16.1 0.0 1.6 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Hydrolase_4 PF12146.3 CDI85723.1 - 0.0054 16.5 0.0 0.012 15.4 0.0 1.6 1 0 0 1 1 1 1 Putative lysophospholipase Abhydrolase_2 PF02230.11 CDI85723.1 - 0.0095 15.4 0.0 0.064 12.6 0.0 2.1 3 0 0 3 3 3 1 Phospholipase/Carboxylesterase FSH1 PF03959.8 CDI85723.1 - 0.012 15.1 0.0 0.025 14.0 0.0 1.6 1 0 0 1 1 1 0 Serine hydrolase (FSH1) Lipase_3 PF01764.20 CDI85723.1 - 0.045 13.3 0.0 0.083 12.5 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) DUF818 PF05677.7 CDI85723.1 - 0.23 10.1 0.0 0.33 9.6 0.0 1.2 1 0 0 1 1 1 0 Chlamydia CHLPS protein (DUF818) SPRY PF00622.23 CDI85724.1 - 3.5e-05 23.8 0.0 6.7e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 SPRY domain TAFII55_N PF04658.8 CDI85725.1 - 2.9e-19 69.1 0.1 2.4e-18 66.1 0.0 2.6 3 0 0 3 3 3 1 TAFII55 protein conserved region Abhydrolase_5 PF12695.2 CDI85727.1 - 2.2e-19 69.6 0.0 4.5e-19 68.6 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CDI85727.1 - 1.4e-14 54.5 0.0 5.5e-13 49.3 0.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CDI85727.1 - 3.4e-09 36.5 0.0 8.7e-06 25.4 0.0 2.2 1 1 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 CDI85727.1 - 7.1e-06 25.3 0.0 1.9e-05 24.0 0.0 1.7 1 1 0 1 1 1 1 Prolyl oligopeptidase family AXE1 PF05448.7 CDI85727.1 - 2.1e-05 23.1 0.0 0.0034 15.9 0.0 3.1 3 1 0 3 3 3 1 Acetyl xylan esterase (AXE1) Peptidase_S15 PF02129.13 CDI85727.1 - 8.4e-05 22.1 0.0 0.00031 20.2 0.0 1.7 2 1 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_2 PF02230.11 CDI85727.1 - 0.00029 20.3 0.0 0.0018 17.7 0.0 2.1 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.8 CDI85727.1 - 0.00056 19.5 0.0 0.00097 18.7 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold FSH1 PF03959.8 CDI85727.1 - 0.001 18.5 0.0 0.0027 17.1 0.0 1.7 1 0 0 1 1 1 1 Serine hydrolase (FSH1) DLH PF01738.13 CDI85727.1 - 0.0036 16.6 0.0 0.032 13.4 0.0 1.9 2 0 0 2 2 2 1 Dienelactone hydrolase family DUF818 PF05677.7 CDI85727.1 - 0.019 13.6 0.0 0.023 13.4 0.0 1.1 1 0 0 1 1 1 0 Chlamydia CHLPS protein (DUF818) BAAT_C PF08840.6 CDI85727.1 - 0.021 14.5 0.0 0.11 12.1 0.0 1.9 1 1 1 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal DUF2305 PF10230.4 CDI85727.1 - 0.064 12.6 0.0 7.2 5.9 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2305) Lipase_3 PF01764.20 CDI85727.1 - 0.092 12.3 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) PTS_EIIC PF02378.13 CDI85727.1 - 0.5 9.1 3.5 2.4 6.8 0.0 2.1 2 0 0 2 2 2 0 Phosphotransferase system, EIIC DUF4482 PF14818.1 CDI85728.1 - 0.026 15.1 4.3 0.031 14.9 0.3 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4482) LRR_6 PF13516.1 CDI85729.1 - 1.6e-06 27.5 10.2 0.7 10.1 0.1 7.6 8 0 0 8 8 8 3 Leucine Rich repeat Sec1 PF00995.18 CDI85729.1 - 0.77 8.3 2.1 1.2 7.6 1.4 1.2 1 0 0 1 1 1 0 Sec1 family SAGA-Tad1 PF12767.2 CDI85729.1 - 5.1 6.6 9.1 9 5.8 6.3 1.4 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit Toxin_56 PF15534.1 CDI85730.1 - 1.6 9.2 4.6 21 5.6 0.3 2.8 2 0 0 2 2 2 0 Putative toxin 56 Nop25 PF09805.4 CDI85731.1 - 10 6.2 30.7 12 5.9 21.3 1.1 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) HC2 PF07382.6 CDI85732.1 - 0.33 10.7 14.4 0.47 10.2 10.0 1.1 1 0 0 1 1 1 0 Histone H1-like nucleoprotein HC2 CAF-1_p150 PF11600.3 CDI85732.1 - 1.5 8.1 47.0 2.3 7.5 32.6 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF4407 PF14362.1 CDI85732.1 - 8.3 5.2 11.9 16 4.3 8.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Pkinase PF00069.20 CDI85734.1 - 7.8e-25 87.5 0.0 9.7e-25 87.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDI85734.1 - 3.5e-05 23.0 0.0 4.8e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase P12 PF12669.2 CDI85735.1 - 0.15 12.3 3.6 0.24 11.6 0.1 2.6 2 0 0 2 2 2 0 Virus attachment protein p12 family CDK2AP PF09806.4 CDI85736.1 - 0.0018 18.5 18.6 0.085 13.0 0.1 2.3 2 0 0 2 2 2 2 Cyclin-dependent kinase 2-associated protein DUF2722 PF10846.3 CDI85736.1 - 0.0024 16.9 11.6 0.12 11.3 0.2 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF2722) Spt20 PF12090.3 CDI85736.1 - 0.0049 16.2 11.7 0.0061 15.9 0.3 2.3 2 0 0 2 2 2 1 Spt20 family Suf PF05843.9 CDI85736.1 - 0.0075 16.0 11.6 0.014 15.1 0.4 2.2 2 0 0 2 2 2 1 Suppressor of forked protein (Suf) Ribosomal_60s PF00428.14 CDI85736.1 - 0.023 15.1 17.8 0.62 10.5 5.2 3.0 3 0 0 3 3 3 0 60s Acidic ribosomal protein FAM176 PF14851.1 CDI85736.1 - 0.024 14.3 8.4 0.39 10.3 0.3 2.4 2 0 0 2 2 2 0 FAM176 family DDHD PF02862.12 CDI85736.1 - 0.027 14.2 2.1 0.6 9.8 0.4 2.2 2 0 0 2 2 2 0 DDHD domain DUF912 PF06024.7 CDI85736.1 - 0.027 14.5 0.1 0.027 14.5 0.1 3.6 3 1 0 3 3 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Afi1 PF07792.7 CDI85736.1 - 0.059 13.3 5.7 3.3 7.7 1.6 2.2 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking OmpH PF03938.9 CDI85736.1 - 0.45 10.4 32.1 2.2 8.2 12.2 2.4 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) EphA2_TM PF14575.1 CDI85736.1 - 0.5 10.8 0.1 0.5 10.8 0.0 3.3 3 0 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain Hid1 PF12722.2 CDI85736.1 - 0.65 7.5 7.5 0.04 11.6 0.2 2.0 2 0 0 2 2 2 0 High-temperature-induced dauer-formation protein LNP1 PF15419.1 CDI85736.1 - 0.74 9.8 10.4 0.15 12.1 3.0 2.1 2 0 0 2 2 2 0 Leukemia NUP98 fusion partner 1 Pex14_N PF04695.8 CDI85736.1 - 0.77 9.8 23.8 0.081 12.9 5.9 2.5 3 0 0 3 3 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF3323 PF11796.3 CDI85736.1 - 0.89 8.8 14.5 0.23 10.7 5.9 2.1 2 0 0 2 2 2 0 Protein of unknown function N-terminus (DUF3323) DUF4175 PF13779.1 CDI85736.1 - 1.2 6.8 39.9 1.1 6.9 14.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4175) Pex16 PF08610.5 CDI85736.1 - 1.3 7.9 12.7 1.9 7.3 2.7 2.2 2 0 0 2 2 2 0 Peroxisomal membrane protein (Pex16) BRF1 PF07741.8 CDI85736.1 - 1.6 8.9 14.9 7.3 6.8 5.1 2.5 2 0 0 2 2 2 0 Brf1-like TBP-binding domain DUF4557 PF15101.1 CDI85736.1 - 3 7.6 22.0 1.2 8.9 5.8 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4557) Ctr PF04145.10 CDI85736.1 - 4.1 7.4 14.0 4.7 7.2 1.6 2.8 2 1 0 2 2 2 0 Ctr copper transporter family AAA_23 PF13476.1 CDI85736.1 - 9.3 6.5 11.8 4 7.7 2.8 2.2 2 0 0 2 2 2 0 AAA domain PCYCGC PF13798.1 CDI85736.1 - 9.7 5.8 8.9 0.91 9.2 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function with PCYCGC motif Dpy-30 PF05186.8 CDI85739.1 - 2 7.9 9.0 0.39 10.2 0.1 3.0 4 0 0 4 4 4 0 Dpy-30 motif SprA-related PF12118.3 CDI85739.1 - 2.6 7.3 53.4 0.46 9.7 18.7 3.2 3 0 0 3 3 3 0 SprA-related family PIG-U PF06728.8 CDI85740.1 - 2.4 6.9 4.0 4.5 6.0 2.6 1.6 1 1 0 1 1 1 0 GPI transamidase subunit PIG-U FAM176 PF14851.1 CDI85740.1 - 2.4 7.7 16.3 0.34 10.5 3.8 2.3 2 0 0 2 2 2 0 FAM176 family Mem_trans PF03547.13 CDI85740.1 - 4.2 5.5 8.6 0.72 8.0 2.9 1.9 2 0 0 2 2 2 0 Membrane transport protein Utp14 PF04615.8 CDI85741.1 - 0.071 11.2 32.6 0.082 11.0 22.6 1.0 1 0 0 1 1 1 0 Utp14 protein Asp-B-Hydro_N PF05279.6 CDI85741.1 - 0.12 12.2 32.8 0.15 11.9 22.8 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region TFIIF_alpha PF05793.7 CDI85741.1 - 0.22 9.8 27.7 0.27 9.5 19.2 1.0 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Macoilin PF09726.4 CDI85741.1 - 0.75 7.9 25.6 0.87 7.7 17.7 1.0 1 0 0 1 1 1 0 Transmembrane protein Daxx PF03344.10 CDI85741.1 - 1.3 7.3 35.1 1.6 7.0 24.4 1.1 1 0 0 1 1 1 0 Daxx Family LMBR1 PF04791.11 CDI85741.1 - 1.4 7.4 7.1 1.7 7.1 4.9 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Mitofilin PF09731.4 CDI85741.1 - 1.5 7.4 37.0 1.9 7.0 25.6 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein SOBP PF15279.1 CDI85741.1 - 2.1 8.6 32.1 2.7 8.2 22.3 1.0 1 0 0 1 1 1 0 Sine oculis-binding protein PLRV_ORF5 PF01690.12 CDI85741.1 - 6.6 5.7 30.2 9 5.3 20.9 1.2 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein DNA_pol_viral_N PF00242.12 CDI85741.1 - 7.5 5.4 24.2 9.7 5.1 16.8 1.1 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain Ebola_NP PF05505.7 CDI85741.1 - 7.6 4.4 24.6 9.8 4.0 17.1 1.1 1 0 0 1 1 1 0 Ebola nucleoprotein SAGA-Tad1 PF12767.2 CDI85741.1 - 9.5 5.7 23.2 13 5.3 16.1 1.3 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit TraG_N PF07916.6 CDI85742.1 - 0.15 10.4 10.9 0.19 10.1 7.6 1.2 1 0 0 1 1 1 0 TraG-like protein, N-terminal region DUF1109 PF06532.6 CDI85742.1 - 1.4 8.2 31.7 1.8 7.9 22.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1109) DUF3357 PF11837.3 CDI85743.1 - 6.9e-05 22.6 9.6 0.0053 16.5 0.5 2.4 1 1 1 2 2 2 2 Domain of unknown function (DUF3357) DUF1510 PF07423.6 CDI85743.1 - 7.5e-05 22.1 14.3 0.0096 15.3 3.9 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1510) IncA PF04156.9 CDI85743.1 - 0.00013 21.6 39.3 0.00088 18.9 16.9 2.2 1 1 1 2 2 2 2 IncA protein EphA2_TM PF14575.1 CDI85743.1 - 0.00013 22.3 13.5 0.037 14.4 0.3 2.6 2 1 0 2 2 2 2 Ephrin type-A receptor 2 transmembrane domain FimP PF09766.4 CDI85743.1 - 0.001 18.1 13.8 0.001 18.1 9.6 2.1 2 0 0 2 2 2 1 Fms-interacting protein UPF0093 PF03653.8 CDI85743.1 - 0.0012 18.8 3.1 0.0012 18.8 2.1 1.9 1 1 1 2 2 2 1 Uncharacterised protein family (UPF0093) Serinc PF03348.10 CDI85743.1 - 0.0034 16.1 11.1 0.0047 15.7 7.7 1.2 1 0 0 1 1 1 1 Serine incorporator (Serinc) DUF2489 PF10675.4 CDI85743.1 - 0.006 16.2 7.3 0.006 16.2 5.1 3.3 2 1 0 2 2 1 1 Protein of unknown function (DUF2489) SpoIIIAH PF12685.2 CDI85743.1 - 0.0067 15.9 17.8 0.64 9.4 12.5 2.2 1 1 0 1 1 1 1 SpoIIIAH-like protein Choline_transpo PF04515.7 CDI85743.1 - 0.011 14.5 0.3 0.034 12.9 0.2 1.7 1 1 0 1 1 1 0 Plasma-membrane choline transporter E7 PF00527.13 CDI85743.1 - 0.015 15.4 15.3 0.084 13.0 0.5 2.3 2 0 0 2 2 2 0 E7 protein, Early protein FA_desaturase PF00487.19 CDI85743.1 - 0.021 14.2 0.1 0.025 14.0 0.1 1.1 1 0 0 1 1 1 0 Fatty acid desaturase DUF4367 PF14285.1 CDI85743.1 - 0.023 14.0 3.6 0.043 13.1 1.9 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4367) DUF2140 PF09911.4 CDI85743.1 - 0.025 13.7 10.5 0.22 10.6 0.6 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2140) CD20 PF04103.10 CDI85743.1 - 0.025 14.5 14.5 0.58 10.0 3.8 2.3 1 1 1 2 2 2 0 CD20-like family PRA1 PF03208.14 CDI85743.1 - 0.027 13.8 4.9 0.025 13.9 1.9 1.8 1 1 1 2 2 2 0 PRA1 family protein Conotoxin PF02950.12 CDI85743.1 - 0.029 15.1 27.8 0.067 13.9 2.1 3.0 1 1 2 3 3 3 0 Conotoxin OSTbeta PF15048.1 CDI85743.1 - 0.039 14.0 11.5 0.63 10.1 3.0 2.2 2 0 0 2 2 2 0 Organic solute transporter subunit beta protein BCS1_N PF08740.6 CDI85743.1 - 0.051 13.1 0.2 0.051 13.1 0.2 2.2 2 0 0 2 2 1 0 BCS1 N terminal FHIPEP PF00771.15 CDI85743.1 - 0.053 11.8 20.0 0.071 11.4 8.5 2.0 1 1 1 2 2 2 0 FHIPEP family Ribosomal_60s PF00428.14 CDI85743.1 - 0.057 13.8 13.5 0.1 12.9 9.4 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein RSN1_TM PF13967.1 CDI85743.1 - 0.067 12.7 2.8 0.081 12.4 0.0 2.0 1 1 1 2 2 2 0 Late exocytosis, associated with Golgi transport 7TM_GPCR_Sru PF10322.4 CDI85743.1 - 0.071 12.1 6.9 0.031 13.3 0.6 2.1 1 1 1 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Sru Nodulin-like PF06813.8 CDI85743.1 - 0.072 12.3 6.8 0.04 13.1 3.0 1.7 1 1 1 2 2 2 0 Nodulin-like DUF2899 PF11449.3 CDI85743.1 - 0.088 11.9 9.2 0.11 11.6 6.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2899) YfhO PF09586.5 CDI85743.1 - 0.1 10.6 15.9 0.17 9.8 11.0 1.3 1 1 0 1 1 1 0 Bacterial membrane protein YfhO CRF1 PF10380.4 CDI85743.1 - 0.12 12.7 10.9 0.19 12.0 3.4 2.1 2 0 0 2 2 2 0 Transcription factor CRF1 DUF929 PF06053.6 CDI85743.1 - 0.18 10.8 7.5 1.1 8.2 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF929) DUF3278 PF11683.3 CDI85743.1 - 0.19 11.7 5.3 1.1 9.2 0.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3278) Ctf8 PF09696.5 CDI85743.1 - 0.21 11.3 0.1 0.21 11.3 0.0 2.2 2 0 0 2 2 2 0 Ctf8 PH_4 PF15404.1 CDI85743.1 - 0.25 10.8 11.7 1.7 8.1 5.2 2.1 2 0 0 2 2 2 0 Pleckstrin homology domain Cytochrom_B_N PF00033.14 CDI85743.1 - 0.25 10.6 2.7 2.5 7.4 1.8 2.0 1 1 0 1 1 1 0 Cytochrome b(N-terminal)/b6/petB Zip PF02535.17 CDI85743.1 - 0.28 10.1 5.4 0.47 9.4 3.7 1.4 1 1 0 1 1 1 0 ZIP Zinc transporter PIG-F PF06699.6 CDI85743.1 - 0.35 10.7 3.1 0.43 10.4 2.1 1.3 1 0 0 1 1 1 0 GPI biosynthesis protein family Pig-F Ctr PF04145.10 CDI85743.1 - 0.37 10.8 15.7 1 9.4 5.4 2.1 1 1 1 2 2 2 0 Ctr copper transporter family DUF418 PF04235.7 CDI85743.1 - 0.39 10.3 8.0 0.54 9.9 2.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF418) Herpes_UL87 PF03043.9 CDI85743.1 - 0.43 8.9 13.0 0.5 8.6 9.0 1.1 1 0 0 1 1 1 0 Herpesvirus UL87 family Ferric_reduct PF01794.14 CDI85743.1 - 0.46 10.5 3.2 5.9 7.0 0.0 2.5 1 1 1 2 2 2 0 Ferric reductase like transmembrane component DUF2569 PF10754.4 CDI85743.1 - 0.47 10.6 4.5 0.67 10.1 1.1 1.9 1 1 0 2 2 2 0 Protein of unknown function (DUF2569) RNase_H2_suC PF08615.6 CDI85743.1 - 0.5 10.1 6.9 4.2 7.2 3.1 2.1 2 0 0 2 2 2 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) Yip1 PF04893.12 CDI85743.1 - 0.5 9.8 6.6 2.7 7.4 4.6 2.0 1 1 0 1 1 1 0 Yip1 domain Pex24p PF06398.6 CDI85743.1 - 0.56 8.9 8.4 11 4.7 5.8 2.0 1 1 0 1 1 1 0 Integral peroxisomal membrane peroxin Lipoprotein_2 PF00921.12 CDI85743.1 - 0.62 10.0 26.3 0.02 14.9 13.6 1.7 2 0 0 2 2 2 0 Borrelia lipoprotein DUF4366 PF14283.1 CDI85743.1 - 0.64 9.3 13.3 2.7 7.3 8.5 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4366) COPI_assoc PF08507.5 CDI85743.1 - 0.69 9.5 5.4 2 8.1 0.7 2.1 1 1 0 2 2 2 0 COPI associated protein DUF2149 PF09919.4 CDI85743.1 - 0.79 9.8 12.9 3.5 7.7 3.7 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2149) PIG-U PF06728.8 CDI85743.1 - 0.84 8.4 8.9 0.36 9.6 1.2 2.1 1 1 1 2 2 2 0 GPI transamidase subunit PIG-U DUF4010 PF13194.1 CDI85743.1 - 0.84 8.8 14.5 1.2 8.3 8.4 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4010) DUF1345 PF07077.6 CDI85743.1 - 0.85 9.1 15.3 1.5 8.2 9.8 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1345) TMEM51 PF15345.1 CDI85743.1 - 0.86 9.2 22.1 0.43 10.2 7.6 2.1 2 0 0 2 2 2 0 Transmembrane protein 51 DUF3474 PF11960.3 CDI85743.1 - 0.92 9.5 5.0 9.5 6.2 2.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3474) 7tm_1 PF00001.16 CDI85743.1 - 0.93 8.5 14.2 0.13 11.4 0.8 2.2 1 1 1 2 2 2 0 7 transmembrane receptor (rhodopsin family) DUF4381 PF14316.1 CDI85743.1 - 1.1 9.2 24.9 0.5 10.4 5.6 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4381) Spore_coat_CotO PF14153.1 CDI85743.1 - 1.2 8.5 22.3 0.2 11.0 7.7 2.1 2 0 0 2 2 2 0 Spore coat protein CotO Rxt3 PF08642.5 CDI85743.1 - 1.2 9.3 7.5 5.8 7.2 2.6 2.2 2 0 0 2 2 2 0 Histone deacetylation protein Rxt3 RskA PF10099.4 CDI85743.1 - 1.6 8.4 39.9 0.41 10.3 1.4 2.8 1 1 0 2 2 2 0 Anti-sigma-K factor rskA DUF3169 PF11368.3 CDI85743.1 - 1.8 7.7 7.5 0.61 9.2 0.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3169) ODV-E18 PF10717.4 CDI85743.1 - 1.9 7.9 5.6 0.37 10.2 0.9 1.9 1 1 1 2 2 2 0 Occlusion-derived virus envelope protein ODV-E18 7TM_GPCR_Str PF10326.4 CDI85743.1 - 2.1 7.4 4.7 2.5 7.1 3.3 1.2 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Str Zn_peptidase PF04228.8 CDI85743.1 - 2.4 7.2 24.2 3.9 6.6 9.3 2.1 1 1 1 2 2 2 0 Putative neutral zinc metallopeptidase Lig_chan PF00060.21 CDI85743.1 - 2.5 7.8 10.9 3.6 7.2 7.5 1.2 1 0 0 1 1 1 0 Ligand-gated ion channel EcsB PF05975.7 CDI85743.1 - 2.7 6.3 11.8 5 5.4 8.2 1.5 1 1 0 1 1 1 0 Bacterial ABC transporter protein EcsB SHR3_chaperone PF08229.6 CDI85743.1 - 2.8 6.8 23.4 1.9 7.3 8.9 2.1 2 0 0 2 2 2 0 ER membrane protein SH3 Nucleoplasmin PF03066.10 CDI85743.1 - 2.9 7.4 9.1 0.68 9.4 1.1 2.1 2 0 0 2 2 2 0 Nucleoplasmin ATAD4 PF15321.1 CDI85743.1 - 3.1 8.8 20.1 17 6.4 0.2 2.2 2 0 0 2 2 2 0 ATPase family AAA domain containing 4 Gti1_Pac2 PF09729.4 CDI85743.1 - 3.2 7.5 10.9 11 5.8 4.9 2.1 2 0 0 2 2 2 0 Gti1/Pac2 family DUF3381 PF11861.3 CDI85743.1 - 3.5 7.1 15.4 0.19 11.2 3.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3381) DUF3112 PF11309.3 CDI85743.1 - 3.9 7.2 7.1 7.1 6.4 4.7 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3112) GPCR_chapero_1 PF11904.3 CDI85743.1 - 3.9 6.5 11.9 6.8 5.7 8.3 1.3 1 1 0 1 1 1 0 GPCR-chaperone Haem_bd PF14376.1 CDI85743.1 - 4.4 6.9 17.9 2.7 7.6 1.0 2.4 2 0 0 2 2 2 0 Haem-binding domain CBP4 PF07960.6 CDI85743.1 - 5 6.7 24.6 5.1 6.7 9.5 2.4 2 0 0 2 2 2 0 CBP4 Rsc14 PF08586.5 CDI85743.1 - 6.5 7.2 9.6 30 5.1 3.4 2.2 2 0 0 2 2 2 0 RSC complex, Rsc14/Ldb7 subunit FAM176 PF14851.1 CDI85743.1 - 6.8 6.3 15.7 5.9 6.5 0.6 2.2 1 1 0 2 2 2 0 FAM176 family DUF940 PF06082.6 CDI85743.1 - 6.8 5.0 16.9 7.5 4.9 11.7 1.0 1 0 0 1 1 1 0 Bacterial putative lipoprotein (DUF940) TerC PF03741.11 CDI85743.1 - 8.3 5.8 12.0 0.76 9.1 3.2 2.0 1 1 1 2 2 2 0 Integral membrane protein TerC family Afaf PF15339.1 CDI85743.1 - 8.6 5.8 11.2 7.2 6.1 1.4 2.2 2 0 0 2 2 2 0 Acrosome formation-associated factor Phage_rep_org_N PF09681.5 CDI85743.1 - 9 5.8 10.5 18 4.8 4.4 2.2 2 0 0 2 2 2 0 N-terminal phage replisome organiser (Phage_rep_org_N) GRP PF07172.6 CDI85743.1 - 9.1 6.8 14.5 4 7.9 1.4 2.5 1 1 2 3 3 2 0 Glycine rich protein family BRF1 PF07741.8 CDI85743.1 - 9.2 6.5 23.6 1.7 8.8 1.0 2.3 2 0 0 2 2 2 0 Brf1-like TBP-binding domain CDC45 PF02724.9 CDI85744.1 - 0.2 9.6 13.1 0.21 9.5 9.1 1.0 1 0 0 1 1 1 0 CDC45-like protein DUF2098 PF09871.4 CDI85744.1 - 0.27 11.2 5.2 0.6 10.0 3.6 1.6 1 1 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2098) SeqA PF03925.8 CDI85744.1 - 0.28 10.8 12.7 0.29 10.7 8.8 1.2 1 0 0 1 1 1 0 SeqA protein SprA-related PF12118.3 CDI85744.1 - 0.39 10.0 37.2 0.39 9.9 25.8 1.0 1 0 0 1 1 1 0 SprA-related family SelP_N PF04592.9 CDI85744.1 - 0.67 9.2 24.1 0.72 9.1 16.7 1.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region DUF3984 PF13136.1 CDI85744.1 - 0.76 8.9 20.5 0.83 8.8 14.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3984) FYDLN_acid PF09538.5 CDI85744.1 - 0.96 10.0 4.9 1.1 9.8 3.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) Acetate_kinase PF00871.12 CDI85744.1 - 1 7.8 5.4 1.3 7.4 3.7 1.1 1 0 0 1 1 1 0 Acetokinase family Autophagy_N PF03986.8 CDI85744.1 - 1.6 8.5 13.6 1.8 8.3 9.4 1.1 1 0 0 1 1 1 0 Autophagocytosis associated protein (Atg3), N-terminal domain Med19 PF10278.4 CDI85744.1 - 1.9 8.1 13.5 1.9 8.1 9.4 1.1 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 Afi1 PF07792.7 CDI85744.1 - 2.8 7.9 17.5 3.2 7.7 12.1 1.2 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking AUX_IAA PF02309.11 CDI85744.1 - 3.2 7.4 15.2 3.4 7.3 10.5 1.1 1 0 0 1 1 1 0 AUX/IAA family Senescence_reg PF04520.8 CDI85744.1 - 3.4 8.1 12.6 4.2 7.8 8.7 1.2 1 0 0 1 1 1 0 Senescence regulator FLO_LFY PF01698.11 CDI85744.1 - 3.5 6.3 17.1 3.6 6.3 11.9 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein RR_TM4-6 PF06459.7 CDI85744.1 - 4 7.2 14.5 4.1 7.2 10.1 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Spore_coat_CotO PF14153.1 CDI85744.1 - 4.1 6.7 24.0 4.3 6.7 16.7 1.1 1 0 0 1 1 1 0 Spore coat protein CotO DDHD PF02862.12 CDI85744.1 - 4.3 7.0 16.0 4.5 7.0 11.1 1.1 1 0 0 1 1 1 0 DDHD domain Gti1_Pac2 PF09729.4 CDI85744.1 - 4.5 7.1 14.5 5.4 6.8 10.0 1.1 1 0 0 1 1 1 0 Gti1/Pac2 family RIC3 PF15361.1 CDI85744.1 - 5.2 7.2 19.2 5.9 7.1 13.3 1.1 1 0 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 Zip PF02535.17 CDI85744.1 - 6.2 5.7 18.7 6 5.7 13.0 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter DUF4512 PF14975.1 CDI85744.1 - 6.4 7.6 8.5 7.5 7.4 5.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4512) Folate_carrier PF01770.13 CDI85744.1 - 6.6 5.1 11.2 6.4 5.1 7.8 1.1 1 0 0 1 1 1 0 Reduced folate carrier Herpes_glycop PF01528.11 CDI85744.1 - 6.7 5.2 9.7 8 5.0 6.7 1.1 1 0 0 1 1 1 0 Herpesvirus glycoprotein M PCEMA1 PF07418.6 CDI85744.1 - 6.9 5.9 10.1 6.6 6.0 7.0 1.0 1 0 0 1 1 1 0 Acidic phosphoprotein precursor PCEMA1 Macoilin PF09726.4 CDI85744.1 - 7.5 4.6 19.2 7.2 4.7 13.3 1.0 1 0 0 1 1 1 0 Transmembrane protein Peptidase_U57 PF05582.7 CDI85744.1 - 7.7 5.3 13.9 7.8 5.3 9.6 1.1 1 0 0 1 1 1 0 YabG peptidase U57 AIF_C PF14721.1 CDI85744.1 - 7.8 6.7 15.6 9 6.5 10.8 1.2 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Dynamin_N PF00350.18 CDI85744.1 - 9.3 6.0 10.6 11 5.8 7.4 1.2 1 0 0 1 1 1 0 Dynamin family DUF4407 PF14362.1 CDI85744.1 - 9.7 5.0 17.6 9.2 5.1 12.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF276 PF03434.8 CDI85745.1 - 0.072 12.0 0.2 0.13 11.2 0.1 1.4 1 0 0 1 1 1 0 DUF276 DUF3881 PF12997.2 CDI85745.1 - 0.088 11.7 6.7 0.096 11.6 0.0 2.5 3 0 0 3 3 3 0 Domain of unknown function, E. rectale Gene description (DUF3881) EphA2_TM PF14575.1 CDI85745.1 - 0.54 10.6 6.4 13 6.2 0.3 3.5 3 0 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain DUF1510 PF07423.6 CDI85746.1 - 0.45 9.8 21.9 0.45 9.8 15.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DUF3807 PF12720.2 CDI85746.1 - 1.6 8.8 28.1 1.8 8.6 19.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) Tim54 PF11711.3 CDI85746.1 - 2.6 6.5 14.7 2.8 6.4 10.2 1.0 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DUF2058 PF09831.4 CDI85746.1 - 3.8 7.3 37.3 4.1 7.2 25.9 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2058) Gti1_Pac2 PF09729.4 CDI85746.1 - 3.9 7.3 16.5 4.6 7.0 11.4 1.1 1 0 0 1 1 1 0 Gti1/Pac2 family Herpes_DNAp_acc PF04929.7 CDI85746.1 - 6.6 5.5 16.3 6.7 5.5 11.3 1.0 1 0 0 1 1 1 0 Herpes DNA replication accessory factor DDHD PF02862.12 CDI85746.1 - 6.6 6.4 21.4 7.1 6.3 14.8 1.0 1 0 0 1 1 1 0 DDHD domain RIC3 PF15361.1 CDI85746.1 - 7.2 6.8 21.0 8.4 6.6 14.6 1.1 1 0 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 DUF2052 PF09747.4 CDI85746.1 - 7.8 6.3 28.2 9.5 6.1 19.6 1.0 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) FimP PF09766.4 CDI85747.1 - 0.0005 19.2 2.5 0.0005 19.2 1.7 1.1 1 0 0 1 1 1 1 Fms-interacting protein Spt20 PF12090.3 CDI85747.1 - 0.0016 17.8 1.7 0.0016 17.8 1.2 1.1 1 0 0 1 1 1 1 Spt20 family DUF3530 PF12048.3 CDI85747.1 - 0.0055 15.7 2.4 0.0065 15.4 1.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3530) DUF4175 PF13779.1 CDI85747.1 - 0.0084 13.8 10.7 0.0084 13.8 7.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4175) Pex16 PF08610.5 CDI85747.1 - 0.0085 15.1 3.4 0.0091 15.0 2.4 1.0 1 0 0 1 1 1 1 Peroxisomal membrane protein (Pex16) RED_N PF07808.8 CDI85747.1 - 0.016 14.4 2.0 0.015 14.5 1.4 1.2 1 0 0 1 1 1 0 RED-like protein N-terminal region FHIPEP PF00771.15 CDI85747.1 - 0.023 13.0 0.9 0.026 12.8 0.6 1.0 1 0 0 1 1 1 0 FHIPEP family DUF3357 PF11837.3 CDI85747.1 - 0.025 14.3 0.1 0.044 13.6 0.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF3357) PSCyt3 PF07627.6 CDI85747.1 - 0.03 14.1 0.8 0.039 13.8 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1588) SARG PF15385.1 CDI85747.1 - 0.031 13.6 3.4 0.036 13.4 2.4 1.1 1 0 0 1 1 1 0 Specifically androgen-regulated gene protein FAM176 PF14851.1 CDI85747.1 - 0.056 13.1 1.9 0.1 12.3 1.3 1.5 1 1 0 1 1 1 0 FAM176 family Suf PF05843.9 CDI85747.1 - 0.068 12.8 5.5 0.065 12.9 3.8 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Pex14_N PF04695.8 CDI85747.1 - 0.11 12.5 9.1 0.15 12.0 6.3 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF2722 PF10846.3 CDI85747.1 - 0.11 11.4 7.0 0.14 11.1 4.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) OATP PF03137.15 CDI85747.1 - 0.11 10.4 1.4 0.12 10.3 1.0 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family DUF3100 PF11299.3 CDI85747.1 - 0.15 11.2 0.3 0.17 11.0 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3100) DivIC PF04977.10 CDI85747.1 - 0.15 11.5 7.6 0.28 10.6 5.3 1.5 1 0 0 1 1 1 0 Septum formation initiator DUF912 PF06024.7 CDI85747.1 - 0.24 11.4 6.3 0.091 12.8 1.9 1.9 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) TMEM51 PF15345.1 CDI85747.1 - 0.3 10.7 6.6 0.32 10.6 4.1 1.4 1 1 0 1 1 1 0 Transmembrane protein 51 NapE PF06796.6 CDI85747.1 - 0.34 10.2 2.9 0.4 10.0 0.8 2.0 2 1 0 2 2 2 0 Periplasmic nitrate reductase protein NapE TraT PF05818.7 CDI85747.1 - 0.37 10.1 3.5 0.49 9.7 2.4 1.1 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein RskA PF10099.4 CDI85747.1 - 0.65 9.7 5.1 0.9 9.2 3.6 1.3 1 1 0 1 1 1 0 Anti-sigma-K factor rskA PAT1 PF09770.4 CDI85747.1 - 0.82 7.8 18.0 0.98 7.5 12.5 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 PNRC PF15365.1 CDI85747.1 - 1 9.4 10.8 1.9 8.5 7.5 1.3 1 0 0 1 1 1 0 Proline-rich nuclear receptor coactivator AAA_23 PF13476.1 CDI85747.1 - 1.6 9.0 5.5 1.9 8.7 3.8 1.1 1 0 0 1 1 1 0 AAA domain DUF4557 PF15101.1 CDI85747.1 - 2.1 8.1 9.8 2.7 7.7 6.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) Kei1 PF08552.6 CDI85747.1 - 2.7 7.6 5.4 2.9 7.5 1.9 1.8 1 1 0 2 2 2 0 Inositolphosphorylceramide synthase subunit Kei1 RAB3GAP2_N PF14655.1 CDI85747.1 - 5.2 5.9 10.1 6.9 5.5 7.0 1.2 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Conotoxin PF02950.12 CDI85747.1 - 5.2 7.9 7.8 3.9 8.3 4.1 1.8 1 1 1 2 2 1 0 Conotoxin PHD_3 PF13922.1 CDI85747.1 - 8.6 6.6 12.5 5.8 7.2 7.3 1.8 2 0 0 2 2 2 0 PHD domain of transcriptional enhancer, Asx Nucleoside_tran PF01733.13 CDI85747.1 - 8.9 5.3 8.3 2.6 7.1 0.1 2.0 1 1 1 2 2 2 0 Nucleoside transporter Caldesmon PF02029.10 CDI85748.1 - 0.00085 17.8 24.5 0.00085 17.8 17.0 2.4 2 1 0 2 2 2 1 Caldesmon Med15 PF09606.5 CDI85748.1 - 0.035 12.3 128.3 0.023 12.9 51.4 2.7 3 0 0 3 3 3 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF1510 PF07423.6 CDI85748.1 - 9.4 5.5 56.7 1 8.6 0.4 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1510) Med15 PF09606.5 CDI85749.1 - 0.0033 15.6 31.9 0.0033 15.6 22.1 4.2 2 1 1 4 4 4 2 ARC105 or Med15 subunit of Mediator complex non-fungal BAF1_ABF1 PF04684.8 CDI85750.1 - 0.0019 17.1 9.7 0.0021 17.0 6.7 1.1 1 0 0 1 1 1 1 BAF1 / ABF1 chromatin reorganising factor Med15 PF09606.5 CDI85750.1 - 0.033 12.4 26.0 0.04 12.1 18.0 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Macoilin PF09726.4 CDI85750.1 - 0.063 11.5 28.9 0.073 11.3 20.0 1.0 1 0 0 1 1 1 0 Transmembrane protein DUF4175 PF13779.1 CDI85750.1 - 0.55 7.8 16.9 0.7 7.5 11.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) AIP3 PF03915.8 CDI85750.1 - 2.6 6.8 16.3 3.2 6.5 11.3 1.1 1 0 0 1 1 1 0 Actin interacting protein 3 Peptidase_S64 PF08192.6 CDI85750.1 - 2.6 6.2 20.5 3.1 6.0 14.2 1.0 1 0 0 1 1 1 0 Peptidase family S64 DUF3744 PF12558.3 CDI85750.1 - 5.5 7.5 11.6 1.1 9.7 4.3 2.4 2 1 1 3 3 3 0 ATP-binding cassette cobalt transporter Spc7_N PF15402.1 CDI85750.1 - 9.4 4.0 25.8 12 3.7 17.9 1.0 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 DctQ PF04290.7 CDI85751.1 - 0.034 13.9 0.6 0.059 13.1 0.4 1.3 1 0 0 1 1 1 0 Tripartite ATP-independent periplasmic transporters, DctQ component GBP PF02263.14 CDI85752.1 - 4.8e-17 61.8 0.0 3.3e-16 59.1 0.0 2.2 1 1 0 1 1 1 1 Guanylate-binding protein, N-terminal domain GBP_C PF02841.9 CDI85752.1 - 5.5e-08 32.3 20.6 4.6e-07 29.3 14.3 1.9 1 1 0 1 1 1 1 Guanylate-binding protein, C-terminal domain Dynamin_N PF00350.18 CDI85752.1 - 2.7 7.7 5.3 2.1 8.1 0.1 2.5 2 0 0 2 2 2 0 Dynamin family Dec-1 PF04624.9 CDI85753.1 - 0.8 9.3 6.0 1.4 8.5 4.1 1.4 1 0 0 1 1 1 0 Dec-1 repeat SOBP PF15279.1 CDI85754.1 - 0.0054 17.1 29.5 0.0065 16.8 20.5 1.0 1 0 0 1 1 1 1 Sine oculis-binding protein Ycf1 PF05758.7 CDI85754.1 - 0.013 13.2 13.8 0.019 12.6 9.6 1.2 1 0 0 1 1 1 0 Ycf1 Med15 PF09606.5 CDI85754.1 - 0.013 13.7 62.4 0.017 13.3 43.3 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal PAT1 PF09770.4 CDI85754.1 - 0.035 12.3 54.6 0.04 12.1 37.8 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Tetraspannin PF00335.15 CDI85754.1 - 0.078 12.2 3.8 0.24 10.6 2.7 1.7 1 1 0 1 1 1 0 Tetraspanin family GAGA_bind PF06217.7 CDI85754.1 - 0.42 10.5 21.4 0.57 10.0 14.8 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family Methyltransf_12 PF08242.7 CDI85754.1 - 2 8.9 7.1 1.9 8.9 0.6 2.1 2 0 0 2 2 2 0 Methyltransferase domain CDC27 PF09507.5 CDI85754.1 - 2 7.5 34.9 2.6 7.1 24.2 1.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 FHIPEP PF00771.15 CDI85754.1 - 2.2 6.5 14.0 0.17 10.1 0.2 2.2 2 0 0 2 2 2 0 FHIPEP family SAPS PF04499.10 CDI85754.1 - 7.3 5.1 24.7 10 4.6 17.1 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein THRAP3_BCLAF1 PF15440.1 CDI85754.1 - 7.3 5.1 42.5 9.3 4.7 29.4 1.0 1 0 0 1 1 1 0 THRAP3/BCLAF1 family DUF3043 PF11241.3 CDI85754.1 - 9.2 5.8 22.1 5.8 6.4 6.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3043) ARF7EP_C PF14949.1 CDI85754.1 - 9.9 6.6 22.2 2.1 8.8 4.4 2.2 2 0 0 2 2 2 0 ARF7 effector protein C-terminus Med15 PF09606.5 CDI85755.1 - 5.4e-05 21.6 97.1 6.8e-05 21.2 67.3 1.0 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal PAT1 PF09770.4 CDI85755.1 - 9.4e-05 20.8 65.7 0.00011 20.6 45.5 1.0 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 Mitofilin PF09731.4 CDI85755.1 - 0.029 13.0 22.6 0.034 12.8 15.7 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Utp14 PF04615.8 CDI85755.1 - 0.21 9.7 30.3 0.23 9.5 21.0 1.0 1 0 0 1 1 1 0 Utp14 protein DDRGK PF09756.4 CDI85755.1 - 3.8 6.8 31.4 1.7 8.0 12.4 2.1 2 0 0 2 2 2 0 DDRGK domain PLRV_ORF5 PF01690.12 CDI85755.1 - 3.9 6.5 31.2 4.8 6.2 21.6 1.0 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein MRP-S31 PF15433.1 CDI85755.1 - 5.3 6.3 32.3 6.5 6.0 22.4 1.2 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 BSMAP PF12280.3 CDI85756.1 - 0.0042 16.9 8.1 0.0049 16.7 5.6 1.0 1 0 0 1 1 1 1 Brain specific membrane anchored protein Peptidase_S49_N PF08496.5 CDI85756.1 - 0.05 13.4 2.7 0.049 13.4 1.9 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF2201_N PF13203.1 CDI85756.1 - 0.12 11.5 9.1 0.11 11.6 6.3 1.0 1 0 0 1 1 1 0 Putative metallopeptidase domain FLO_LFY PF01698.11 CDI85756.1 - 0.14 11.0 6.4 0.13 11.1 4.4 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein Baculo_PP31 PF05311.6 CDI85756.1 - 0.17 11.1 4.6 0.16 11.2 3.2 1.1 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) DUF1491 PF07372.7 CDI85756.1 - 0.18 11.7 3.4 0.22 11.4 2.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1491) FimP PF09766.4 CDI85756.1 - 0.18 10.8 17.3 0.21 10.6 12.0 1.1 1 0 0 1 1 1 0 Fms-interacting protein Serinc PF03348.10 CDI85756.1 - 0.19 10.3 6.3 0.2 10.3 4.3 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) DUF3260 PF11658.3 CDI85756.1 - 0.2 9.7 4.8 0.21 9.7 3.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3260) DUF913 PF06025.7 CDI85756.1 - 0.22 10.2 3.1 0.24 10.1 2.2 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Hid1 PF12722.2 CDI85756.1 - 0.23 9.0 4.9 0.19 9.3 3.4 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein PAT1 PF09770.4 CDI85756.1 - 0.34 9.0 23.6 0.31 9.2 16.4 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Zip PF02535.17 CDI85756.1 - 0.36 9.7 1.6 0.37 9.7 1.1 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter Folate_carrier PF01770.13 CDI85756.1 - 0.51 8.8 3.2 0.52 8.7 2.2 1.2 1 0 0 1 1 1 0 Reduced folate carrier UPF0560 PF10577.4 CDI85756.1 - 1.3 7.2 14.8 1.1 7.3 10.2 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Plasmodium_Vir PF05795.6 CDI85756.1 - 1.7 7.7 4.3 1.9 7.6 2.9 1.0 1 0 0 1 1 1 0 Plasmodium vivax Vir protein eIF-3_zeta PF05091.7 CDI85756.1 - 1.9 6.9 14.3 1.9 7.0 9.9 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF4199 PF13858.1 CDI85756.1 - 2.4 8.0 4.7 3.4 7.5 3.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) RR_TM4-6 PF06459.7 CDI85756.1 - 2.4 7.9 8.9 2.5 7.8 6.1 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 MMR1 PF08505.5 CDI85756.1 - 2.6 8.0 12.6 2.2 8.2 8.7 1.0 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein DUF1764 PF08576.5 CDI85756.1 - 2.9 8.7 13.5 3.5 8.4 9.3 1.1 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) Anoctamin PF04547.7 CDI85756.1 - 3.1 6.3 5.5 3.2 6.2 3.8 1.1 1 0 0 1 1 1 0 Calcium-activated chloride channel DUF4407 PF14362.1 CDI85756.1 - 3.9 6.3 12.0 4 6.3 8.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF775 PF05603.7 CDI85756.1 - 4.3 6.8 9.9 4.9 6.6 6.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF775) LIM_bind PF01803.11 CDI85756.1 - 5.5 6.0 13.5 7.2 5.6 9.4 1.1 1 0 0 1 1 1 0 LIM-domain binding protein DDHD PF02862.12 CDI85756.1 - 5.8 6.6 10.1 6.5 6.4 7.0 1.1 1 0 0 1 1 1 0 DDHD domain Suf PF05843.9 CDI85756.1 - 6.1 6.4 13.0 8.5 6.0 9.0 1.4 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) TSA PF03249.8 CDI85757.1 - 0.41 9.1 6.3 0.44 9.0 4.4 1.1 1 0 0 1 1 1 0 Type specific antigen Shadoo PF14999.1 CDI85759.1 - 0.00049 19.9 4.5 0.04 13.7 0.6 2.4 2 0 0 2 2 2 2 Shadow of prion protein, neuroprotective K_channel_TID PF07941.6 CDI85759.1 - 0.18 12.0 24.8 1.9 8.7 5.5 3.2 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain DUF4131 PF13567.1 CDI85759.1 - 0.72 9.2 11.9 0.11 11.8 3.4 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4131) LRR_8 PF13855.1 CDI85760.1 - 0.053 13.2 41.5 0.28 10.9 5.1 4.3 3 1 1 4 4 4 0 Leucine rich repeat Asp-B-Hydro_N PF05279.6 CDI85761.1 - 0.049 13.4 20.5 0.067 13.0 14.2 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region PAT1 PF09770.4 CDI85761.1 - 0.07 11.3 58.2 0.082 11.1 40.3 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF4045 PF13254.1 CDI85761.1 - 0.19 10.9 19.4 0.22 10.7 13.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Med15 PF09606.5 CDI85761.1 - 0.29 9.2 84.4 0.33 9.1 58.5 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal SAGA-Tad1 PF12767.2 CDI85761.1 - 0.36 10.4 27.3 0.52 9.9 18.9 1.4 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit Tyrosinase PF00264.15 CDI85761.1 - 0.66 10.0 9.1 0.8 9.8 6.3 1.2 1 0 0 1 1 1 0 Common central domain of tyrosinase TFIIA PF03153.8 CDI85761.1 - 0.84 9.4 42.2 1 9.2 29.2 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Cyto_heme_lyase PF01265.12 CDI85761.1 - 1.8 8.1 25.2 2.4 7.6 17.5 1.1 1 0 0 1 1 1 0 Cytochrome c/c1 heme lyase Hid1 PF12722.2 CDI85761.1 - 2.2 5.8 26.2 2.6 5.6 18.2 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SAPS PF04499.10 CDI85761.1 - 2.6 6.5 19.3 2.9 6.4 13.4 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein PLRV_ORF5 PF01690.12 CDI85761.1 - 3.8 6.5 23.1 4.4 6.3 16.0 1.0 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein DUF1675 PF07897.6 CDI85761.1 - 4.2 7.1 21.2 4.9 6.9 14.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) DUF4613 PF15390.1 CDI85761.1 - 4.5 5.3 19.4 5.3 5.0 13.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) GAGA_bind PF06217.7 CDI85761.1 - 9.7 6.0 23.1 11 5.8 16.0 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family CRT10 PF08728.5 CDI85761.1 - 9.9 4.0 12.9 11 3.8 8.9 1.1 1 0 0 1 1 1 0 CRT10 Mucin PF01456.12 CDI85762.1 - 0.01 15.6 10.9 0.01 15.6 7.6 3.6 4 0 0 4 4 4 0 Mucin-like glycoprotein DDHD PF02862.12 CDI85762.1 - 0.7 9.6 19.5 0.66 9.7 4.8 2.4 2 0 0 2 2 2 0 DDHD domain Tn7_Tnp_TnsA_C PF08721.6 CDI85762.1 - 0.89 9.6 7.9 0.096 12.7 1.5 2.3 2 1 0 2 2 2 0 TnsA endonuclease C terminal CD20 PF04103.10 CDI85762.1 - 1.4 8.8 9.3 11 5.9 2.9 3.6 2 1 0 2 2 2 0 CD20-like family PAT1 PF09770.4 CDI85762.1 - 4.5 5.3 64.6 6.8 4.7 44.8 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 S1 PF00575.18 CDI85763.1 - 7.9e-05 22.6 0.0 0.00015 21.7 0.0 1.4 1 0 0 1 1 1 1 S1 RNA binding domain CAF-1_p150 PF11600.3 CDI85763.1 - 0.00058 19.2 3.3 0.00058 19.2 2.3 2.6 1 1 2 3 3 3 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal EntA_Immun PF08951.5 CDI85763.1 - 0.025 14.7 0.2 0.044 13.9 0.1 1.4 1 0 0 1 1 1 0 Enterocin A Immunity Polysacc_synt_3 PF13440.1 CDI85763.1 - 2.6 7.4 10.2 0.51 9.7 1.5 2.1 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein FAM220 PF15487.1 CDI85763.1 - 7.6 5.8 19.2 0.82 8.9 0.1 2.1 2 0 0 2 2 2 0 FAM220 family Uds1 PF15456.1 CDI85764.1 - 0.21 11.6 12.5 0.22 11.5 8.7 1.1 1 0 0 1 1 1 0 Up-regulated During Septation MRC1 PF09444.5 CDI85764.1 - 0.58 10.4 6.5 0.67 10.2 4.5 1.2 1 0 0 1 1 1 0 MRC1-like domain FCP1_C PF09309.5 CDI85764.1 - 0.85 8.8 9.3 0.98 8.6 6.5 1.1 1 0 0 1 1 1 0 FCP1, C-terminal PilX PF13681.1 CDI85764.1 - 1.7 9.2 7.6 2 8.9 5.3 1.2 1 0 0 1 1 1 0 Type IV pilus assembly protein PilX C-term PFEMP PF03011.10 CDI85764.1 - 2.2 8.5 12.4 2.4 8.5 8.6 1.1 1 0 0 1 1 1 0 PFEMP DBL domain DUF1168 PF06658.7 CDI85764.1 - 3.2 7.2 17.2 3.4 7.1 11.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) Pex14_N PF04695.8 CDI85764.1 - 3.5 7.6 21.7 6.9 6.7 15.0 1.5 1 1 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region G-7-MTase PF12803.2 CDI85764.1 - 9.6 5.2 10.1 9.8 5.2 7.0 1.0 1 0 0 1 1 1 0 mRNA (guanine-7-)methyltransferase (G-7-MTase) CAF-1_p150 PF11600.3 CDI85765.1 - 0.00047 19.6 20.6 0.00058 19.3 14.3 1.2 1 0 0 1 1 1 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF4512 PF14975.1 CDI85765.1 - 0.003 18.3 0.9 0.0062 17.3 0.7 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4512) FimP PF09766.4 CDI85765.1 - 0.013 14.5 18.4 0.011 14.7 12.8 1.1 1 0 0 1 1 1 0 Fms-interacting protein Med15 PF09606.5 CDI85765.1 - 0.028 12.6 40.0 0.027 12.7 27.7 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF3801 PF12687.2 CDI85765.1 - 0.098 12.2 11.5 0.12 11.9 8.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3801) Suf PF05843.9 CDI85765.1 - 0.11 12.2 20.0 0.11 12.1 13.9 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF737 PF05300.6 CDI85765.1 - 0.3 11.0 17.6 0.37 10.7 12.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF737) FHIPEP PF00771.15 CDI85765.1 - 0.31 9.3 4.1 0.28 9.4 2.9 1.1 1 0 0 1 1 1 0 FHIPEP family RR_TM4-6 PF06459.7 CDI85765.1 - 0.65 9.8 10.1 0.73 9.6 7.0 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 EPL1 PF10513.4 CDI85765.1 - 0.74 10.0 12.9 0.9 9.7 8.9 1.1 1 0 0 1 1 1 0 Enhancer of polycomb-like DUF4603 PF15376.1 CDI85765.1 - 0.84 6.7 18.3 0.93 6.6 12.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) eIF-3_zeta PF05091.7 CDI85765.1 - 0.88 8.1 14.3 0.81 8.2 9.9 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Apt1 PF10351.4 CDI85765.1 - 1.1 8.0 18.7 1.2 7.9 12.9 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Raftlin PF15250.1 CDI85765.1 - 1.5 7.2 16.6 1.6 7.1 11.5 1.0 1 0 0 1 1 1 0 Raftlin Cellulose_synt PF03552.9 CDI85765.1 - 1.8 6.7 6.3 1.8 6.7 4.4 1.1 1 0 0 1 1 1 0 Cellulose synthase FLO_LFY PF01698.11 CDI85765.1 - 1.9 7.2 13.7 2 7.2 9.5 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein AUX_IAA PF02309.11 CDI85765.1 - 2.5 7.8 13.6 3.3 7.4 9.4 1.2 1 0 0 1 1 1 0 AUX/IAA family Zip PF02535.17 CDI85765.1 - 3.1 6.6 9.3 3.5 6.5 6.4 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter Corona_nucleoca PF00937.13 CDI85765.1 - 3.2 6.6 24.8 3.9 6.3 17.2 1.1 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein XRCC4 PF06632.7 CDI85765.1 - 3.5 6.3 12.3 3.8 6.2 8.5 1.0 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 DUF4220 PF13968.1 CDI85765.1 - 3.6 6.5 5.7 3.9 6.4 4.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4220) SoxE PF06525.6 CDI85765.1 - 3.6 6.8 6.6 6 6.1 4.6 1.3 1 0 0 1 1 1 0 Sulfocyanin (SoxE) TFIIA PF03153.8 CDI85765.1 - 4.8 6.9 26.8 6.4 6.5 18.6 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Het-C PF07217.6 CDI85765.1 - 6.3 4.8 9.4 6.4 4.8 6.5 1.1 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C DUF913 PF06025.7 CDI85765.1 - 8.7 4.9 10.2 9.7 4.8 7.1 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Herpes_DNAp_acc PF04929.7 CDI85765.1 - 8.8 5.1 16.9 10 4.9 11.7 1.0 1 0 0 1 1 1 0 Herpes DNA replication accessory factor G0-G1_switch_2 PF15103.1 CDI85765.1 - 9.4 6.5 9.4 12 6.1 6.5 1.3 1 0 0 1 1 1 0 G0/G1 switch protein 2 SOBP PF15279.1 CDI85767.1 - 2e-05 25.1 36.0 0.0075 16.6 7.1 2.1 2 0 0 2 2 2 2 Sine oculis-binding protein Spt20 PF12090.3 CDI85767.1 - 0.059 12.7 21.7 0.023 14.0 1.8 2.4 2 0 0 2 2 2 0 Spt20 family FimP PF09766.4 CDI85767.1 - 0.21 10.6 39.8 0.73 8.8 7.9 2.3 2 0 0 2 2 2 0 Fms-interacting protein zf-DHHC PF01529.15 CDI85767.1 - 1 8.7 7.9 4.1 6.7 0.0 2.2 2 0 0 2 2 2 0 DHHC palmitoyltransferase Med15 PF09606.5 CDI85768.1 - 0.014 13.6 94.4 0.02 13.1 65.4 1.3 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Spc7 PF08317.6 CDI85769.1 - 5.3 5.5 40.0 0.5 8.9 15.5 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein Med15 PF09606.5 CDI85769.1 - 6.4 4.8 43.8 11 4.1 30.3 1.3 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Clat_adaptor_s PF01217.15 CDI85770.1 - 0.027 14.2 0.1 0.042 13.5 0.0 1.3 1 0 0 1 1 1 0 Clathrin adaptor complex small chain BAF1_ABF1 PF04684.8 CDI85771.1 - 0.0021 16.9 17.9 0.0021 16.9 12.4 2.0 1 1 1 2 2 1 1 BAF1 / ABF1 chromatin reorganising factor Conotoxin PF02950.12 CDI85771.1 - 0.016 15.9 4.2 0.016 15.9 2.9 2.4 2 1 0 2 2 2 0 Conotoxin EphA2_TM PF14575.1 CDI85771.1 - 0.02 15.2 0.4 0.02 15.2 0.3 2.3 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain WBP-1 PF11669.3 CDI85771.1 - 0.028 14.5 0.6 0.028 14.5 0.4 2.2 2 0 0 2 2 1 0 WW domain-binding protein 1 DUF1510 PF07423.6 CDI85771.1 - 0.032 13.5 8.8 0.039 13.3 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) G-7-MTase PF12803.2 CDI85771.1 - 0.046 12.8 0.3 0.046 12.8 0.2 1.8 2 0 0 2 2 2 0 mRNA (guanine-7-)methyltransferase (G-7-MTase) DUF3357 PF11837.3 CDI85771.1 - 0.047 13.5 0.8 0.047 13.5 0.6 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF3357) PCYCGC PF13798.1 CDI85771.1 - 0.087 12.5 0.3 0.087 12.5 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function with PCYCGC motif DUF4446 PF14584.1 CDI85771.1 - 0.23 11.2 3.5 1.6 8.5 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) FimP PF09766.4 CDI85771.1 - 0.23 10.4 22.3 0.17 10.8 2.8 2.1 2 0 0 2 2 2 0 Fms-interacting protein Neur_chan_memb PF02932.11 CDI85771.1 - 0.23 11.2 4.3 0.3 10.9 3.0 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region GRP PF07172.6 CDI85771.1 - 0.24 11.9 0.3 0.24 11.9 0.2 2.1 2 0 0 2 2 2 0 Glycine rich protein family Endonuc_Holl PF10107.4 CDI85771.1 - 0.26 10.9 7.1 0.24 11.0 0.6 2.1 2 0 0 2 2 2 0 Endonuclease related to archaeal Holliday junction resolvase Herpes_UL49_5 PF05702.6 CDI85771.1 - 0.38 10.6 2.0 16 5.4 0.5 2.3 2 0 0 2 2 2 0 Herpesvirus UL49.5 envelope/tegument protein DUF3371 PF11851.3 CDI85771.1 - 0.52 11.0 21.5 0.14 12.8 3.7 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3371) TMEM51 PF15345.1 CDI85771.1 - 0.53 9.9 14.8 0.23 11.1 2.6 2.1 2 0 0 2 2 2 0 Transmembrane protein 51 Folliculin PF11704.3 CDI85771.1 - 0.79 9.2 5.5 1.3 8.5 0.2 2.1 2 0 0 2 2 2 0 Vesicle coat protein involved in Golgi to plasma membrane transport APC_CDC26 PF10471.4 CDI85771.1 - 0.84 10.4 31.5 2.5 8.9 9.6 2.5 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit 1 SpoIIIAH PF12685.2 CDI85771.1 - 1.1 8.7 16.8 5 6.5 11.7 1.8 1 1 0 1 1 1 0 SpoIIIAH-like protein Mem_trans PF03547.13 CDI85771.1 - 2.3 6.4 4.9 4.7 5.4 1.2 1.9 1 1 1 2 2 2 0 Membrane transport protein Herpes_DNAp_acc PF04929.7 CDI85771.1 - 3 6.7 11.0 7.2 5.4 7.6 1.6 1 1 0 1 1 1 0 Herpes DNA replication accessory factor ATAD4 PF15321.1 CDI85771.1 - 3.5 8.6 12.3 4.8 8.2 1.0 2.2 2 0 0 2 2 2 0 ATPase family AAA domain containing 4 CDK2AP PF09806.4 CDI85771.1 - 5 7.3 25.6 0.77 9.9 7.6 2.1 2 0 0 2 2 2 0 Cyclin-dependent kinase 2-associated protein OSTbeta PF15048.1 CDI85771.1 - 5.4 7.1 9.9 0.11 12.5 0.4 2.1 2 0 0 2 2 2 0 Organic solute transporter subunit beta protein DUF4557 PF15101.1 CDI85771.1 - 5.7 6.7 22.9 5.6 6.7 3.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4557) E7 PF00527.13 CDI85771.1 - 6.4 6.9 11.4 7.1 6.8 0.8 2.2 2 0 0 2 2 2 0 E7 protein, Early protein Peptidase_S64 PF08192.6 CDI85771.1 - 7.6 4.7 11.3 8.8 4.5 7.8 1.0 1 0 0 1 1 1 0 Peptidase family S64 MRI PF15325.1 CDI85771.1 - 7.9 7.4 7.0 2.5 9.0 0.4 2.0 2 0 0 2 2 2 0 Modulator of retrovirus infection IncA PF04156.9 CDI85771.1 - 8.9 5.8 24.7 2.6 7.6 3.3 2.2 2 0 0 2 2 2 0 IncA protein Agouti PF05039.7 CDI85771.1 - 9.6 6.6 9.1 3.8 7.9 0.5 2.3 2 0 0 2 2 2 0 Agouti protein DUF4414 PF14377.1 CDI85772.1 - 0.0027 17.5 2.8 0.0027 17.5 1.9 2.4 2 1 0 2 2 2 1 Domain of unknown function (DUF4414) SprA-related PF12118.3 CDI85772.1 - 0.0027 17.0 24.4 0.004 16.5 16.9 1.3 1 0 0 1 1 1 1 SprA-related family RRN3 PF05327.6 CDI85772.1 - 0.014 13.5 2.8 0.022 12.8 1.9 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 RskA PF10099.4 CDI85772.1 - 0.12 12.1 7.9 0.3 10.8 5.3 1.8 1 1 0 1 1 1 0 Anti-sigma-K factor rskA Hex_IIIa PF02455.11 CDI85772.1 - 0.13 10.8 10.1 0.16 10.6 7.0 1.0 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) VIT1 PF01988.14 CDI85772.1 - 0.17 11.3 5.7 0.28 10.6 4.0 1.2 1 0 0 1 1 1 0 VIT family NMDAR2_C PF10565.4 CDI85772.1 - 0.24 10.0 18.4 0.34 9.5 12.7 1.2 1 0 0 1 1 1 0 N-methyl D-aspartate receptor 2B3 C-terminus FHIPEP PF00771.15 CDI85772.1 - 0.26 9.5 1.6 0.39 9.0 1.1 1.2 1 0 0 1 1 1 0 FHIPEP family DUF4613 PF15390.1 CDI85772.1 - 0.47 8.5 9.5 0.54 8.3 6.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) Mitofilin PF09731.4 CDI85772.1 - 0.57 8.7 15.5 0.66 8.5 10.7 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein DUF2217 PF10265.4 CDI85772.1 - 0.6 8.8 12.8 0.68 8.6 8.9 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) Lipoprotein_2 PF00921.12 CDI85772.1 - 0.62 10.0 9.8 0.96 9.4 6.8 1.3 1 0 0 1 1 1 0 Borrelia lipoprotein DUF3337 PF11816.3 CDI85772.1 - 0.66 9.3 10.4 0.8 9.0 7.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3337) Peptidase_S64 PF08192.6 CDI85772.1 - 0.71 8.1 12.6 0.84 7.8 8.7 1.1 1 0 0 1 1 1 0 Peptidase family S64 RR_TM4-6 PF06459.7 CDI85772.1 - 0.81 9.5 12.6 1.2 8.9 8.7 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 RED_N PF07808.8 CDI85772.1 - 1.2 8.3 10.4 0.56 9.3 3.4 2.2 2 0 0 2 2 2 0 RED-like protein N-terminal region APC8 PF04049.8 CDI85772.1 - 1.2 8.8 11.8 0.11 12.2 3.5 2.1 2 0 0 2 2 2 0 Anaphase promoting complex subunit 8 / Cdc23 SAPS PF04499.10 CDI85772.1 - 1.3 7.5 8.5 1.7 7.1 5.9 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Hamartin PF04388.7 CDI85772.1 - 1.7 7.2 14.1 1.9 7.0 9.8 1.1 1 0 0 1 1 1 0 Hamartin protein CDC27 PF09507.5 CDI85772.1 - 1.9 7.6 22.1 2.5 7.2 15.3 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Afi1 PF07792.7 CDI85772.1 - 2.3 8.2 9.5 4.2 7.3 2.6 2.1 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Tom22 PF04281.8 CDI85772.1 - 2.9 7.4 10.7 0.16 11.4 2.1 2.3 2 0 0 2 2 2 0 Mitochondrial import receptor subunit Tom22 PAT1 PF09770.4 CDI85772.1 - 3.3 5.8 19.8 4.5 5.3 13.7 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 FimP PF09766.4 CDI85772.1 - 3.9 6.4 14.2 0.29 10.1 5.4 1.9 2 0 0 2 2 2 0 Fms-interacting protein CytochromB561_N PF09786.4 CDI85772.1 - 4.2 5.6 14.8 5.6 5.2 10.2 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal Herpes_TAF50 PF03326.8 CDI85772.1 - 4.6 6.0 23.1 6 5.6 16.0 1.1 1 0 0 1 1 1 0 Herpesvirus transcription activation factor (transactivator) Parvo_coat PF00740.13 CDI85772.1 - 5 5.9 10.5 6.1 5.6 7.2 1.1 1 0 0 1 1 1 0 Parvovirus coat protein VP2 MSP1_C PF07462.6 CDI85772.1 - 5.4 5.2 10.9 7.3 4.8 7.5 1.2 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus DUF533 PF04391.7 CDI85772.1 - 5.6 6.3 20.5 6.8 6.0 9.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF533) DUF966 PF06136.8 CDI85772.1 - 7.4 5.8 18.0 11 5.3 12.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Pap_E4 PF02711.9 CDI85772.1 - 9.1 7.1 13.2 4.3 8.2 3.1 2.3 2 0 0 2 2 2 0 E4 protein Secretin_N_2 PF07655.8 CDI85772.1 - 9.8 6.6 17.7 39 4.7 10.5 2.4 2 0 0 2 2 2 0 Secretin N-terminal domain SNF2_N PF00176.18 CDI85773.1 - 4.8e-33 114.2 7.3 4.3e-29 101.2 0.0 3.3 3 0 0 3 3 3 2 SNF2 family N-terminal domain zf-RING_2 PF13639.1 CDI85773.1 - 4.5e-06 26.3 9.1 4.5e-06 26.3 6.3 3.4 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4_2 PF13923.1 CDI85773.1 - 0.00011 22.1 5.6 0.00011 22.1 3.9 3.3 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 CDI85773.1 - 0.00029 20.4 8.6 0.00045 19.8 4.9 2.2 1 1 0 1 1 1 1 RING-type zinc-finger PAT1 PF09770.4 CDI85773.1 - 0.0012 17.2 63.3 0.0012 17.2 43.9 6.8 7 0 0 7 7 7 1 Topoisomerase II-associated protein PAT1 zf-C3HC4 PF00097.20 CDI85773.1 - 0.0012 18.4 6.1 0.0012 18.4 4.2 2.9 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Med15 PF09606.5 CDI85774.1 - 0.025 12.7 13.9 0.027 12.7 9.7 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF3451 PF11933.3 CDI85774.1 - 0.029 14.1 6.8 0.048 13.4 4.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3451) Ycf1 PF05758.7 CDI85774.1 - 0.031 12.0 5.1 0.031 12.0 3.5 1.1 1 0 0 1 1 1 0 Ycf1 Zip PF02535.17 CDI85774.1 - 0.037 13.0 2.9 0.044 12.7 2.0 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter DUF787 PF05619.6 CDI85774.1 - 0.098 11.3 0.0 0.13 10.9 0.0 1.1 1 0 0 1 1 1 0 Borrelia burgdorferi protein of unknown function (DUF787) PBP1_TM PF14812.1 CDI85774.1 - 0.13 12.5 3.9 0.28 11.5 2.7 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF4175 PF13779.1 CDI85774.1 - 0.25 8.9 20.4 0.37 8.4 14.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Presenilin PF01080.12 CDI85774.1 - 0.47 9.2 4.1 0.72 8.6 2.9 1.3 1 0 0 1 1 1 0 Presenilin Peptidase_S15 PF02129.13 CDI85774.1 - 0.47 9.8 4.6 0.11 11.8 1.2 1.4 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) Hid1 PF12722.2 CDI85774.1 - 0.51 7.9 5.0 0.5 7.9 3.5 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Prog_receptor PF02161.10 CDI85774.1 - 0.68 8.6 7.1 0.87 8.3 4.9 1.1 1 0 0 1 1 1 0 Progesterone receptor Glyco_transf_6 PF03414.8 CDI85774.1 - 0.93 7.8 4.2 1.4 7.3 2.9 1.2 1 0 0 1 1 1 0 Glycosyltransferase family 6 DUF1764 PF08576.5 CDI85774.1 - 1.2 9.9 11.3 0.24 12.1 5.3 1.7 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF1764) Herpes_UL87 PF03043.9 CDI85774.1 - 2.2 6.5 9.9 4.4 5.5 6.8 1.5 1 1 1 2 2 2 0 Herpesvirus UL87 family AUX_IAA PF02309.11 CDI85774.1 - 3 7.5 10.1 5.6 6.6 7.0 1.4 1 0 0 1 1 1 0 AUX/IAA family Spore_coat_CotO PF14153.1 CDI85774.1 - 3 7.2 18.0 1.4 8.3 9.6 2.0 2 0 0 2 2 2 0 Spore coat protein CotO MRI PF15325.1 CDI85774.1 - 3.2 8.7 11.7 5 8.1 4.7 2.3 2 0 0 2 2 2 0 Modulator of retrovirus infection Paf1 PF03985.8 CDI85774.1 - 5.2 5.7 15.4 7.9 5.1 10.6 1.2 1 0 0 1 1 1 0 Paf1 DUF2052 PF09747.4 CDI85774.1 - 5.2 6.9 19.8 0.33 10.8 9.8 1.7 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) DUF1510 PF07423.6 CDI85774.1 - 6.2 6.1 15.8 0.41 9.9 7.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) RR_TM4-6 PF06459.7 CDI85774.1 - 9.3 6.0 13.9 0.39 10.5 5.8 1.5 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 LETM1 PF07766.8 CDI85775.1 - 0.0072 15.4 10.0 0.0082 15.2 6.9 1.0 1 0 0 1 1 1 1 LETM1-like protein OATP PF03137.15 CDI85775.1 - 0.015 13.3 11.8 0.018 13.1 8.2 1.0 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Serinc PF03348.10 CDI85775.1 - 0.035 12.8 15.4 0.036 12.7 10.7 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) Dala_Dala_lig_N PF01820.16 CDI85775.1 - 0.094 13.0 5.0 0.099 12.9 3.4 1.1 1 0 0 1 1 1 0 D-ala D-ala ligase N-terminus Ycf1 PF05758.7 CDI85775.1 - 0.11 10.2 10.9 0.11 10.1 7.5 1.0 1 0 0 1 1 1 0 Ycf1 RIC3 PF15361.1 CDI85775.1 - 0.17 12.1 10.6 0.19 11.9 7.3 1.1 1 0 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 DUF913 PF06025.7 CDI85775.1 - 0.24 10.1 4.4 0.22 10.2 3.0 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DUF4220 PF13968.1 CDI85775.1 - 0.25 10.4 5.3 0.25 10.3 3.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4220) DUF3700 PF12481.3 CDI85775.1 - 0.26 10.4 2.9 0.28 10.3 2.0 1.1 1 0 0 1 1 1 0 Aluminium induced protein CPSF100_C PF13299.1 CDI85775.1 - 0.28 11.3 8.1 0.29 11.3 5.6 1.0 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Tim54 PF11711.3 CDI85775.1 - 0.28 9.7 6.7 0.28 9.7 4.6 1.0 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Band_3_cyto PF07565.8 CDI85775.1 - 0.3 10.5 12.4 0.32 10.4 8.6 1.0 1 0 0 1 1 1 0 Band 3 cytoplasmic domain DUF912 PF06024.7 CDI85775.1 - 0.34 10.9 7.7 0.49 10.4 5.3 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) FYDLN_acid PF09538.5 CDI85775.1 - 0.35 11.4 4.4 0.41 11.2 3.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) AAA_11 PF13086.1 CDI85775.1 - 0.46 10.0 10.3 0.46 10.0 7.1 1.0 1 0 0 1 1 1 0 AAA domain Folate_carrier PF01770.13 CDI85775.1 - 0.48 8.8 8.1 0.5 8.8 5.6 1.0 1 0 0 1 1 1 0 Reduced folate carrier CagX PF03524.10 CDI85775.1 - 0.49 9.6 11.4 0.7 9.1 7.9 1.3 1 0 0 1 1 1 0 Conjugal transfer protein BORG_CEP PF14957.1 CDI85775.1 - 0.52 11.2 6.4 0.57 11.1 4.4 1.1 1 0 0 1 1 1 0 Cdc42 effector Suf PF05843.9 CDI85775.1 - 0.54 9.9 18.4 0.67 9.6 12.8 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Cas_Cmr3 PF09700.5 CDI85775.1 - 0.54 9.6 4.2 0.57 9.5 2.9 1.0 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Cmr3) CRF1 PF10380.4 CDI85775.1 - 0.59 10.4 8.1 0.63 10.3 5.6 1.1 1 0 0 1 1 1 0 Transcription factor CRF1 Baculo_PP31 PF05311.6 CDI85775.1 - 0.62 9.2 13.5 0.7 9.1 9.4 1.0 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) Paf1 PF03985.8 CDI85775.1 - 0.67 8.6 17.8 0.8 8.3 12.4 1.1 1 0 0 1 1 1 0 Paf1 AUX_IAA PF02309.11 CDI85775.1 - 0.71 9.5 8.9 0.77 9.4 6.2 1.1 1 0 0 1 1 1 0 AUX/IAA family DUF4512 PF14975.1 CDI85775.1 - 0.72 10.7 5.6 0.87 10.4 3.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4512) Tau95 PF09734.4 CDI85775.1 - 0.79 8.9 11.7 0.87 8.8 8.1 1.1 1 0 0 1 1 1 0 RNA polymerase III transcription factor (TF)IIIC subunit RR_TM4-6 PF06459.7 CDI85775.1 - 0.86 9.4 13.1 0.98 9.2 9.1 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 FAM60A PF15396.1 CDI85775.1 - 1 9.0 9.3 1.2 8.8 6.4 1.1 1 0 0 1 1 1 0 Protein Family FAM60A Trypan_glycop_C PF10659.4 CDI85775.1 - 1.1 9.5 9.1 1.5 9.1 6.3 1.2 1 0 0 1 1 1 0 Trypanosome variant surface glycoprotein C-terminal domain Zip PF02535.17 CDI85775.1 - 1.1 8.1 6.6 1.2 8.0 4.6 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter Peptidase_S49_N PF08496.5 CDI85775.1 - 1.1 9.0 13.6 1.4 8.7 9.4 1.0 1 0 0 1 1 1 0 Peptidase family S49 N-terminal HGTP_anticodon2 PF12745.2 CDI85775.1 - 1.1 8.3 12.0 1.2 8.1 8.3 1.0 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs Peroxin-13_N PF04088.8 CDI85775.1 - 1.2 9.0 7.5 1.4 8.8 5.2 1.1 1 0 0 1 1 1 0 Peroxin 13, N-terminal region Kei1 PF08552.6 CDI85775.1 - 1.4 8.5 10.1 1.6 8.3 7.0 1.0 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 DUF2126 PF09899.4 CDI85775.1 - 1.4 6.8 10.6 1.6 6.7 7.4 1.0 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) AAA_28 PF13521.1 CDI85775.1 - 1.5 8.7 8.7 2 8.3 6.0 1.2 1 0 0 1 1 1 0 AAA domain AIF_C PF14721.1 CDI85775.1 - 1.5 9.0 12.4 1.8 8.7 8.6 1.1 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Gti1_Pac2 PF09729.4 CDI85775.1 - 1.5 8.6 10.0 1.7 8.4 7.0 1.1 1 0 0 1 1 1 0 Gti1/Pac2 family DUF4647 PF15504.1 CDI85775.1 - 1.6 7.5 17.5 1.7 7.4 12.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4647) YABBY PF04690.8 CDI85775.1 - 1.7 8.8 9.1 1.9 8.7 6.3 1.0 1 0 0 1 1 1 0 YABBY protein eIF_4EBP PF05456.6 CDI85775.1 - 1.8 8.2 9.5 2.5 7.8 6.6 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) DUF3043 PF11241.3 CDI85775.1 - 1.8 8.0 9.3 2.3 7.7 6.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) PAT1 PF09770.4 CDI85775.1 - 1.9 6.6 37.4 2.1 6.5 26.0 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF3675 PF12428.3 CDI85775.1 - 2 8.6 7.1 2.3 8.4 4.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3675) DUF4602 PF15375.1 CDI85775.1 - 2.1 8.3 17.7 2.5 8.1 12.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4602) SeqA PF03925.8 CDI85775.1 - 2.2 7.9 11.7 2.6 7.7 8.1 1.0 1 0 0 1 1 1 0 SeqA protein DUF3306 PF11748.3 CDI85775.1 - 2.2 8.9 12.7 2.7 8.6 8.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3306) DUF2828 PF11443.3 CDI85775.1 - 2.3 6.3 9.7 2.5 6.2 6.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) EIIBC-GUT_N PF03612.9 CDI85775.1 - 2.3 7.7 11.0 2.6 7.6 7.6 1.1 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus GOLD_2 PF13897.1 CDI85775.1 - 2.4 8.3 5.6 2.9 8.1 3.9 1.1 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking Bul1_N PF04425.7 CDI85775.1 - 2.4 6.5 14.3 2.6 6.5 9.9 1.0 1 0 0 1 1 1 0 Bul1 N terminus DUF2946 PF11162.3 CDI85775.1 - 2.6 8.2 7.5 3.5 7.8 5.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2946) DUF2370 PF10176.4 CDI85775.1 - 2.7 7.2 8.2 2.9 7.1 5.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) SID-1_RNA_chan PF13965.1 CDI85775.1 - 2.7 6.0 7.1 2.9 5.9 4.9 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Peptidase_S15 PF02129.13 CDI85775.1 - 2.7 7.3 11.9 2.8 7.2 8.3 1.0 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Afi1 PF07792.7 CDI85775.1 - 2.7 7.9 17.0 3.1 7.7 11.8 1.1 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Glyco_transf_15 PF01793.11 CDI85775.1 - 3.2 6.6 14.3 3.8 6.3 9.9 1.1 1 0 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase DUF4045 PF13254.1 CDI85775.1 - 3.2 6.9 10.4 3.7 6.7 7.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Nucleoside_tran PF01733.13 CDI85775.1 - 3.7 6.6 7.9 4 6.4 5.5 1.0 1 0 0 1 1 1 0 Nucleoside transporter HD-ZIP_N PF04618.7 CDI85775.1 - 3.7 8.1 6.5 4.5 7.8 4.5 1.2 1 0 0 1 1 1 0 HD-ZIP protein N terminus Hid1 PF12722.2 CDI85775.1 - 3.7 5.1 15.0 4 4.9 10.4 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein MDFI PF15316.1 CDI85775.1 - 4 7.3 6.4 4 7.3 4.4 1.1 1 0 0 1 1 1 0 MyoD family inhibitor FimP PF09766.4 CDI85775.1 - 4.1 6.3 30.9 5.8 5.8 21.4 1.2 1 0 0 1 1 1 0 Fms-interacting protein DUF1800 PF08811.6 CDI85775.1 - 4.2 6.1 16.0 4.5 6.0 11.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1800) DUF2347 PF09804.4 CDI85775.1 - 4.3 6.5 9.1 4.6 6.4 6.3 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2347) DNA_pol3_a_NII PF11490.3 CDI85775.1 - 5.1 6.7 23.7 6.2 6.4 16.5 1.1 1 0 0 1 1 1 0 DNA polymerase III polC-type N-terminus II Presenilin PF01080.12 CDI85775.1 - 5.6 5.6 7.1 6 5.5 4.9 1.0 1 0 0 1 1 1 0 Presenilin PBP1_TM PF14812.1 CDI85775.1 - 5.7 7.3 7.6 7.8 6.8 5.3 1.2 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal eIF3_subunit PF08597.5 CDI85775.1 - 5.8 6.4 15.2 6.9 6.1 10.6 1.0 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit TFIIA PF03153.8 CDI85775.1 - 6 6.6 27.2 6.6 6.5 18.8 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF605 PF04652.11 CDI85775.1 - 6.4 6.0 23.6 7 5.9 16.4 1.0 1 0 0 1 1 1 0 Vta1 like ATAD4 PF15321.1 CDI85775.1 - 6.4 7.8 14.1 9.3 7.3 9.8 1.3 1 0 0 1 1 1 0 ATPase family AAA domain containing 4 DUF1764 PF08576.5 CDI85775.1 - 6.8 7.5 17.6 8.5 7.2 12.2 1.1 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) DDHD PF02862.12 CDI85775.1 - 7 6.3 14.0 8.5 6.0 9.7 1.0 1 0 0 1 1 1 0 DDHD domain Dynamin_N PF00350.18 CDI85775.1 - 7 6.4 9.3 7.8 6.2 6.4 1.1 1 0 0 1 1 1 0 Dynamin family FHIPEP PF00771.15 CDI85775.1 - 7.1 4.8 9.8 7.5 4.7 6.8 1.1 1 0 0 1 1 1 0 FHIPEP family DUF106 PF01956.11 CDI85775.1 - 7.3 6.0 12.6 7.6 6.0 8.7 1.1 1 0 0 1 1 1 0 Integral membrane protein DUF106 Med19 PF10278.4 CDI85775.1 - 7.4 6.2 12.1 8.4 6.0 8.4 1.1 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 FLO_LFY PF01698.11 CDI85775.1 - 7.4 5.3 14.4 8.9 5.0 10.0 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein G-alpha PF00503.15 CDI85775.1 - 7.8 5.0 13.4 8.7 4.9 9.3 1.0 1 0 0 1 1 1 0 G-protein alpha subunit TraH_2 PF06871.6 CDI85775.1 - 8.4 5.7 7.1 9.5 5.6 4.9 1.0 1 0 0 1 1 1 0 TraH_2 ARF7EP_C PF14949.1 CDI85775.1 - 8.7 6.8 14.3 10 6.5 9.9 1.1 1 0 0 1 1 1 0 ARF7 effector protein C-terminus Ctr PF04145.10 CDI85775.1 - 8.8 6.3 10.1 11 6.0 7.0 1.1 1 0 0 1 1 1 0 Ctr copper transporter family Cellulose_synt PF03552.9 CDI85775.1 - 8.9 4.4 6.3 9.3 4.3 4.3 1.0 1 0 0 1 1 1 0 Cellulose synthase Neur_chan_memb PF02932.11 CDI85775.1 - 9.2 6.0 9.6 11 5.8 6.7 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Nrap PF03813.9 CDI85779.1 - 3.7e-61 206.8 0.0 3.4e-40 137.4 0.0 3.1 2 1 0 2 2 2 2 Nrap protein Ank_2 PF12796.2 CDI85781.1 - 2.6e-35 120.6 0.0 1.8e-20 73.0 0.0 3.3 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 CDI85781.1 - 1.1e-29 100.6 3.9 2.1e-07 30.4 0.0 6.4 6 0 0 6 6 6 4 Ankyrin repeat Ank_4 PF13637.1 CDI85781.1 - 2.1e-22 79.0 0.0 4.4e-13 49.3 0.0 4.2 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 CDI85781.1 - 4.5e-22 77.5 0.0 4.6e-08 33.0 0.0 5.3 2 2 3 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 CDI85781.1 - 7.4e-22 75.2 0.4 8.8e-05 22.3 0.0 6.2 6 0 0 6 6 6 3 Ankyrin repeat Trichoplein PF13868.1 CDI85783.1 - 6.6e-48 162.8 144.4 6.6e-48 162.8 100.1 2.2 1 1 1 2 2 2 1 Tumour suppressor, Mitostatin dCMP_cyt_deam_1 PF00383.17 CDI85783.1 - 0.098 12.3 0.5 0.78 9.4 0.1 2.4 2 0 0 2 2 2 0 Cytidine and deoxycytidylate deaminase zinc-binding region RPAP2_Rtr1 PF04181.8 CDI85784.1 - 0.0014 18.6 0.5 0.0014 18.6 0.4 2.1 2 0 0 2 2 2 1 Rtr1/RPAP2 family HTH_32 PF13565.1 CDI85784.1 - 2 9.2 5.1 8.2 7.3 0.0 3.7 4 0 0 4 4 4 0 Homeodomain-like domain Cpn10 PF00166.16 CDI85785.1 - 3.4e-15 55.7 0.0 4.5e-15 55.3 0.0 1.2 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit Cas_csx3 PF09620.5 CDI85785.1 - 0.018 14.8 0.0 0.03 14.1 0.0 1.4 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_csx3) ThiF PF00899.16 CDI85786.1 - 3.5e-35 120.7 0.0 9.3e-35 119.4 0.0 1.7 1 1 0 1 1 1 1 ThiF family MoeZ_MoeB PF05237.8 CDI85786.1 - 0.0008 18.9 0.8 0.002 17.6 0.1 2.1 2 0 0 2 2 2 1 MoeZ/MoeB domain NAD_binding_7 PF13241.1 CDI85786.1 - 0.0072 16.5 0.3 0.053 13.7 0.2 2.1 1 1 0 1 1 1 1 Putative NAD(P)-binding Saccharop_dh PF03435.13 CDI85786.1 - 0.026 13.4 0.2 3.3 6.5 0.0 2.2 2 0 0 2 2 2 0 Saccharopine dehydrogenase Shikimate_DH PF01488.15 CDI85786.1 - 0.077 13.0 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Arm PF00514.18 CDI85787.1 - 0.00017 21.2 19.1 0.26 11.1 0.0 9.0 10 0 0 10 10 10 3 Armadillo/beta-catenin-like repeat YqfQ PF14181.1 CDI85788.1 - 8.3 6.4 9.5 1 9.3 0.2 2.6 3 0 0 3 3 3 0 YqfQ-like protein AAA PF00004.24 CDI85789.1 - 9.6e-05 22.5 0.0 0.00017 21.7 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RNase_H2-Ydr279 PF09468.5 CDI85791.1 - 4.9 6.2 9.5 4.9 6.2 6.6 1.0 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) PglZ PF08665.7 CDI85791.1 - 5.1 6.7 11.9 5.7 6.5 8.3 1.0 1 0 0 1 1 1 0 PglZ domain Fes1 PF08609.5 CDI85791.1 - 5.7 7.4 12.2 6.5 7.3 8.4 1.1 1 0 0 1 1 1 0 Nucleotide exchange factor Fes1 Pex14_N PF04695.8 CDI85791.1 - 7.2 6.6 26.2 9.2 6.3 18.2 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF1211 PF06736.6 CDI85792.1 - 0.0013 18.8 0.1 0.0017 18.4 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1211) Serinc PF03348.10 CDI85792.1 - 0.06 12.0 2.9 0.072 11.8 2.0 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) PAT1 PF09770.4 CDI85792.1 - 0.54 8.4 32.5 0.63 8.2 22.5 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF3499 PF12005.3 CDI85792.1 - 0.77 9.9 8.8 4.1 7.5 0.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3499) GBP PF02263.14 CDI85792.1 - 0.82 8.6 12.3 2.4 7.1 7.0 2.0 1 1 1 2 2 2 0 Guanylate-binding protein, N-terminal domain CRT10 PF08728.5 CDI85792.1 - 1 7.2 6.7 1 7.2 4.6 1.0 1 0 0 1 1 1 0 CRT10 AUX_IAA PF02309.11 CDI85792.1 - 1.4 8.6 5.3 1.8 8.2 3.6 1.2 1 0 0 1 1 1 0 AUX/IAA family DUF3457 PF11939.3 CDI85792.1 - 3.2 7.2 15.0 9.2e+02 -0.8 10.4 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF3457) DUF4175 PF13779.1 CDI85792.1 - 3.6 5.1 32.5 5.1 4.6 22.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) G0-G1_switch_2 PF15103.1 CDI85792.1 - 4 7.7 11.6 2.6 8.3 0.4 2.1 2 0 0 2 2 2 0 G0/G1 switch protein 2 Nse4_C PF08743.5 CDI85792.1 - 7.6 6.6 9.8 5.9 6.9 1.4 2.3 1 1 0 2 2 2 0 Nse4 C-terminal SPT6_acidic PF14632.1 CDI85792.1 - 8.2 6.6 7.8 6.7 6.9 2.6 2.3 2 0 0 2 2 2 0 Acidic N-terminal SPT6 DUF1645 PF07816.6 CDI85793.1 - 9 6.7 23.4 4.8 7.6 2.3 3.8 4 0 0 4 4 4 0 Protein of unknown function (DUF1645) PHD_3 PF13922.1 CDI85793.1 - 9.6 6.5 7.3 32 4.8 5.0 1.8 1 0 0 1 1 1 0 PHD domain of transcriptional enhancer, Asx zf-DHHC PF01529.15 CDI85794.1 - 0.25 10.7 3.0 0.56 9.5 2.0 1.6 2 0 0 2 2 2 0 DHHC palmitoyltransferase Spt20 PF12090.3 CDI85794.1 - 0.41 9.9 10.4 0.48 9.7 5.9 1.8 2 0 0 2 2 2 0 Spt20 family Tocopherol_cycl PF14249.1 CDI85794.1 - 0.46 9.1 6.8 0.64 8.6 4.7 1.1 1 0 0 1 1 1 0 Tocopherol cyclase Folate_carrier PF01770.13 CDI85794.1 - 0.54 8.7 1.9 0.87 8.0 1.3 1.3 1 0 0 1 1 1 0 Reduced folate carrier FimP PF09766.4 CDI85794.1 - 0.76 8.7 19.6 0.015 14.3 8.5 1.7 2 0 0 2 2 2 0 Fms-interacting protein DUF912 PF06024.7 CDI85794.1 - 0.83 9.7 7.3 27 4.8 3.7 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF4463 PF14703.1 CDI85794.1 - 0.85 10.1 5.1 14 6.2 0.5 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4463) Suf PF05843.9 CDI85794.1 - 1 9.0 14.1 1.6 8.4 8.6 1.8 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) DUF3675 PF12428.3 CDI85794.1 - 1.1 9.4 3.6 1 9.6 1.4 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3675) FCP1_C PF09309.5 CDI85794.1 - 1.2 8.4 11.6 0.034 13.4 3.4 1.8 2 0 0 2 2 2 0 FCP1, C-terminal TRM13 PF05206.9 CDI85794.1 - 1.5 7.9 9.9 3.7 6.7 0.4 2.1 2 0 0 2 2 2 0 Methyltransferase TRM13 AUX_IAA PF02309.11 CDI85794.1 - 4.8 6.8 7.8 1.1 8.9 3.2 1.5 2 0 0 2 2 2 0 AUX/IAA family Tim54 PF11711.3 CDI85794.1 - 6 5.3 7.7 0.41 9.1 1.8 1.6 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 Serinc PF03348.10 CDI85794.1 - 9.7 4.7 8.0 11 4.6 4.8 1.5 2 0 0 2 2 2 0 Serine incorporator (Serinc) ACC_epsilon PF13822.1 CDI85795.1 - 0.02 15.2 5.6 0.02 15.2 3.9 3.8 2 1 0 2 2 2 0 Acyl-CoA carboxylase epsilon subunit DUF1720 PF08226.6 CDI85796.1 - 0.0038 17.2 34.7 0.0038 17.2 24.1 4.8 1 1 2 3 3 3 1 Domain of unknown function (DUF1720) V_ATPase_I PF01496.14 CDI85797.1 - 5.3e-31 107.2 9.1 5.3e-31 107.2 6.3 2.2 1 1 1 2 2 1 1 V-type ATPase 116kDa subunit family DUF1510 PF07423.6 CDI85797.1 - 4.6e-05 22.8 16.7 0.00014 21.3 2.3 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1510) FimP PF09766.4 CDI85797.1 - 0.0004 19.5 28.2 0.025 13.6 5.5 2.2 2 0 0 2 2 2 2 Fms-interacting protein DUF3408 PF11888.3 CDI85797.1 - 0.00068 19.5 4.0 0.00068 19.5 2.8 2.4 2 1 0 2 2 2 1 Protein of unknown function (DUF3408) EphA2_TM PF14575.1 CDI85797.1 - 0.015 15.6 15.9 0.58 10.5 0.7 3.3 3 0 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain DUF4064 PF13273.1 CDI85797.1 - 0.016 15.3 0.1 0.016 15.3 0.0 3.1 2 1 0 2 2 1 0 Protein of unknown function (DUF4064) DUF2201_N PF13203.1 CDI85797.1 - 0.035 13.2 13.9 0.15 11.1 1.6 2.2 2 0 0 2 2 2 0 Putative metallopeptidase domain DUF912 PF06024.7 CDI85797.1 - 0.041 13.9 14.3 0.44 10.6 0.7 3.4 3 1 0 3 3 3 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Herpes_UL87 PF03043.9 CDI85797.1 - 0.066 11.5 5.2 0.14 10.5 3.6 1.4 1 1 0 1 1 1 0 Herpesvirus UL87 family FNIP_N PF14636.1 CDI85797.1 - 0.094 13.1 17.8 0.29 11.6 3.3 2.1 2 0 0 2 2 2 0 Folliculin-interacting protein N-terminus Baculo_PP31 PF05311.6 CDI85797.1 - 0.12 11.6 13.6 0.48 9.6 1.8 2.2 2 0 0 2 2 2 0 Baculovirus 33KDa late protein (PP31) FAM176 PF14851.1 CDI85797.1 - 0.13 11.9 8.9 2.1 8.0 0.4 3.0 3 0 0 3 3 3 0 FAM176 family BTV_NS2 PF04514.7 CDI85797.1 - 0.58 8.9 13.9 1.1 8.1 2.6 2.1 2 0 0 2 2 2 0 Bluetongue virus non-structural protein NS2 RIC3 PF15361.1 CDI85797.1 - 0.61 10.3 24.2 0.79 9.9 6.6 2.4 2 1 0 2 2 2 0 Resistance to inhibitors of cholinesterase homologue 3 Neur_chan_memb PF02932.11 CDI85797.1 - 0.95 9.3 15.8 2.3 8.0 11.0 1.6 1 1 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region CcmH PF03918.9 CDI85797.1 - 1 8.3 13.8 0.23 10.4 0.3 3.1 3 0 0 3 3 3 0 Cytochrome C biogenesis protein Conotoxin PF02950.12 CDI85797.1 - 1.3 9.8 19.0 1.1 10.1 1.5 3.2 3 0 0 3 3 3 0 Conotoxin Herpes_DNAp_acc PF04929.7 CDI85797.1 - 1.4 7.7 15.1 2.5 6.9 2.5 2.1 2 0 0 2 2 2 0 Herpes DNA replication accessory factor Spore_coat_CotO PF14153.1 CDI85797.1 - 1.6 8.1 30.7 0.45 9.9 7.2 2.3 2 0 0 2 2 2 0 Spore coat protein CotO DUF775 PF05603.7 CDI85797.1 - 2.1 7.7 21.7 1.1 8.7 2.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF775) DUF605 PF04652.11 CDI85797.1 - 2.3 7.5 25.3 1.1 8.6 4.4 2.1 2 0 0 2 2 2 0 Vta1 like Gastrin PF00918.12 CDI85797.1 - 2.4 8.9 24.7 1.3 9.8 5.4 2.3 2 0 0 2 2 2 0 Gastrin/cholecystokinin family Kei1 PF08552.6 CDI85797.1 - 2.4 7.7 17.7 0.3 10.7 1.0 2.1 1 1 0 2 2 2 0 Inositolphosphorylceramide synthase subunit Kei1 Band_3_cyto PF07565.8 CDI85797.1 - 2.5 7.5 20.5 1.8 7.9 3.7 2.2 2 0 0 2 2 2 0 Band 3 cytoplasmic domain Spt20 PF12090.3 CDI85797.1 - 2.6 7.3 34.9 0.22 10.8 9.5 2.3 2 1 0 2 2 2 0 Spt20 family Spore_YhcN_YlaJ PF09580.5 CDI85797.1 - 2.9 7.9 16.2 1.3 9.1 2.1 2.2 2 0 0 2 2 2 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) SprA-related PF12118.3 CDI85797.1 - 3.5 6.8 46.9 2.9 7.1 12.7 2.1 2 0 0 2 2 2 0 SprA-related family FLO_LFY PF01698.11 CDI85797.1 - 3.6 6.3 21.3 2.3 6.9 2.2 2.1 2 0 0 2 2 2 0 Floricaula / Leafy protein Peptidase_S49_N PF08496.5 CDI85797.1 - 4.3 7.1 26.7 3.2 7.5 6.5 2.3 1 1 1 2 2 2 0 Peptidase family S49 N-terminal DUF3357 PF11837.3 CDI85797.1 - 5.9 6.7 13.8 4.4 7.1 0.3 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF3357) Eapp_C PF10238.4 CDI85797.1 - 6.4 6.6 16.5 0.94 9.3 0.9 2.9 3 0 0 3 3 3 0 E2F-associated phosphoprotein Rer1 PF03248.8 CDI85797.1 - 6.8 6.2 9.4 0.084 12.4 0.2 2.2 3 0 0 3 3 3 0 Rer1 family GRP PF07172.6 CDI85797.1 - 7.6 7.0 18.8 3 8.3 0.1 3.2 2 1 1 3 3 3 0 Glycine rich protein family Zip PF02535.17 CDI85797.1 - 9.9 5.0 12.3 1.3e+02 1.4 8.5 2.0 1 1 0 1 1 1 0 ZIP Zinc transporter PPP4R2 PF09184.6 CDI85798.1 - 0.23 10.9 45.4 0.26 10.8 31.5 1.0 1 0 0 1 1 1 0 PPP4R2 DUF21 PF01595.15 CDI85799.1 - 0.013 14.7 0.3 0.013 14.7 0.2 2.2 2 1 0 2 2 2 0 Domain of unknown function DUF21 Phostensin_N PF13916.1 CDI85799.1 - 0.021 14.7 4.1 0.043 13.8 2.9 1.6 1 0 0 1 1 1 0 PP1-regulatory protein, Phostensin N-terminal Ndc1_Nup PF09531.5 CDI85799.1 - 0.67 8.3 19.7 0.91 7.8 13.6 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup PAT1 PF09770.4 CDI85799.1 - 1.2 7.3 31.6 1.3 7.1 21.9 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Utp14 PF04615.8 CDI85799.1 - 2.3 6.2 26.5 2.7 6.0 18.4 1.0 1 0 0 1 1 1 0 Utp14 protein DNA_pol_viral_N PF00242.12 CDI85799.1 - 2.4 7.0 33.9 2.9 6.8 23.5 1.1 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain Macoilin PF09726.4 CDI85799.1 - 2.4 6.3 39.9 3 5.9 27.7 1.0 1 0 0 1 1 1 0 Transmembrane protein Tmemb_cc2 PF10267.4 CDI85799.1 - 4.4 5.7 21.2 5.5 5.4 14.7 1.2 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein CytochromB561_N PF09786.4 CDI85799.1 - 5.4 5.3 31.5 6.2 5.1 21.8 1.0 1 0 0 1 1 1 0 Cytochrome B561, N terminal SLD3 PF08639.5 CDI85799.1 - 7.6 5.0 29.0 9.6 4.7 20.1 1.2 1 0 0 1 1 1 0 DNA replication regulator SLD3 DUF4259 PF14078.1 CDI85801.1 - 0.079 13.4 1.5 0.087 13.3 1.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4259) RskA PF10099.4 CDI85801.1 - 0.085 12.5 7.2 0.1 12.3 5.0 1.1 1 0 0 1 1 1 0 Anti-sigma-K factor rskA FimP PF09766.4 CDI85801.1 - 0.16 11.0 9.9 0.16 11.0 6.9 1.2 1 0 0 1 1 1 0 Fms-interacting protein DUF2229 PF09989.4 CDI85801.1 - 0.17 11.3 3.4 0.18 11.2 2.3 1.0 1 0 0 1 1 1 0 CoA enzyme activase uncharacterised domain (DUF2229) SprA-related PF12118.3 CDI85801.1 - 0.22 10.8 23.1 0.25 10.6 16.0 1.0 1 0 0 1 1 1 0 SprA-related family CDK2AP PF09806.4 CDI85801.1 - 0.37 11.0 13.8 0.45 10.7 9.5 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein DUF2360 PF10152.4 CDI85801.1 - 0.41 10.9 8.3 0.52 10.5 5.7 1.2 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) RAB3GAP2_N PF14655.1 CDI85801.1 - 0.49 9.3 8.2 0.55 9.1 5.7 1.1 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus VIT1 PF01988.14 CDI85801.1 - 0.66 9.4 2.9 0.85 9.0 2.0 1.1 1 0 0 1 1 1 0 VIT family Rtf2 PF04641.7 CDI85801.1 - 0.67 9.1 8.5 0.68 9.0 5.9 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger DDHD PF02862.12 CDI85801.1 - 0.72 9.6 7.6 0.84 9.3 5.3 1.1 1 0 0 1 1 1 0 DDHD domain Herpes_DNAp_acc PF04929.7 CDI85801.1 - 0.89 8.4 7.6 1 8.2 5.2 1.0 1 0 0 1 1 1 0 Herpes DNA replication accessory factor FAM60A PF15396.1 CDI85801.1 - 0.97 9.1 6.5 0.97 9.1 4.5 1.1 1 0 0 1 1 1 0 Protein Family FAM60A Presenilin PF01080.12 CDI85801.1 - 1 8.0 7.3 1 8.1 5.1 1.0 1 0 0 1 1 1 0 Presenilin Med15 PF09606.5 CDI85801.1 - 1.1 7.3 20.9 1.2 7.2 14.5 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal FNIP_N PF14636.1 CDI85801.1 - 1.1 9.6 8.8 1.4 9.4 6.1 1.2 1 0 0 1 1 1 0 Folliculin-interacting protein N-terminus MDFI PF15316.1 CDI85801.1 - 1.2 9.1 6.1 1.3 8.9 4.2 1.1 1 0 0 1 1 1 0 MyoD family inhibitor TFIIA PF03153.8 CDI85801.1 - 1.3 8.8 18.2 1.3 8.8 12.6 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RR_TM4-6 PF06459.7 CDI85801.1 - 1.6 8.6 8.7 1.6 8.5 6.0 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Spore_coat_CotO PF14153.1 CDI85801.1 - 2 7.8 14.0 2 7.8 9.7 1.1 1 0 0 1 1 1 0 Spore coat protein CotO Gag_spuma PF03276.9 CDI85801.1 - 2.4 6.3 12.2 3 6.0 8.4 1.2 1 0 0 1 1 1 0 Spumavirus gag protein Suf PF05843.9 CDI85801.1 - 2.6 7.6 10.6 2.8 7.5 7.4 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Serinc PF03348.10 CDI85801.1 - 3.6 6.1 5.5 3.8 6.1 3.8 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) DHHW PF14286.1 CDI85801.1 - 6.1 6.0 7.8 6.1 6.0 5.4 1.1 1 0 0 1 1 1 0 DHHW protein DUF2201_N PF13203.1 CDI85801.1 - 8 5.5 16.1 9.2 5.3 11.2 1.0 1 0 0 1 1 1 0 Putative metallopeptidase domain DUF913 PF06025.7 CDI85801.1 - 8.5 5.0 8.2 9.8 4.8 5.7 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Claudin_2 PF13903.1 CDI85802.1 - 0.00086 19.0 0.1 0.0011 18.7 0.0 1.2 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction DUF4231 PF14015.1 CDI85802.1 - 0.029 14.3 3.5 0.038 13.9 2.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4231) FHIPEP PF00771.15 CDI85802.1 - 0.057 11.7 7.1 0.066 11.5 4.9 1.0 1 0 0 1 1 1 0 FHIPEP family Spt20 PF12090.3 CDI85802.1 - 0.071 12.4 4.9 0.072 12.4 3.4 1.2 1 0 0 1 1 1 0 Spt20 family CD20 PF04103.10 CDI85802.1 - 0.093 12.6 2.0 0.19 11.6 1.4 1.4 1 0 0 1 1 1 0 CD20-like family IncA PF04156.9 CDI85802.1 - 0.12 11.9 11.9 0.095 12.2 7.4 1.4 1 1 0 1 1 1 0 IncA protein Med15 PF09606.5 CDI85802.1 - 0.22 9.6 35.5 0.27 9.3 24.6 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Zip PF02535.17 CDI85802.1 - 0.34 9.8 8.6 0.36 9.7 6.0 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Suf PF05843.9 CDI85802.1 - 0.41 10.3 14.8 0.5 10.0 10.3 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) CDK5_activator PF03261.10 CDI85802.1 - 0.45 9.7 7.0 0.51 9.6 4.8 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein Hid1 PF12722.2 CDI85802.1 - 0.51 7.9 5.2 0.5 7.9 3.6 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein PAT1 PF09770.4 CDI85802.1 - 0.53 8.4 28.8 0.55 8.4 19.9 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 RskA PF10099.4 CDI85802.1 - 0.9 9.2 28.9 4.8 6.8 10.6 2.1 1 1 1 2 2 2 0 Anti-sigma-K factor rskA Hamartin PF04388.7 CDI85802.1 - 1.4 7.4 13.6 1.8 7.1 9.4 1.0 1 0 0 1 1 1 0 Hamartin protein DUF1675 PF07897.6 CDI85802.1 - 1.6 8.5 8.3 2 8.2 5.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) FLO_LFY PF01698.11 CDI85802.1 - 1.9 7.2 12.7 2.2 7.0 8.8 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein RAB3GAP2_N PF14655.1 CDI85802.1 - 2.2 7.1 8.5 2.9 6.8 5.9 1.3 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus BTV_NS2 PF04514.7 CDI85802.1 - 2.5 6.8 7.3 3.1 6.5 5.0 1.0 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Mif2_N PF15624.1 CDI85802.1 - 2.6 8.6 9.9 3.5 8.2 6.9 1.2 1 0 0 1 1 1 0 Kinetochore CENP-C fungal homologue, Mif2, N-terminal DUF3807 PF12720.2 CDI85802.1 - 2.9 8.0 18.4 4.7 7.3 12.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) DUF3533 PF12051.3 CDI85802.1 - 5.4 5.6 5.7 5.2 5.7 3.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3533) R_equi_Vir PF05526.6 CDI85802.1 - 5.6 6.5 13.6 7.9 6.0 9.4 1.3 1 0 0 1 1 1 0 Rhodococcus equi virulence-associated protein Neur_chan_memb PF02932.11 CDI85802.1 - 6.2 6.6 9.2 6.8 6.4 6.4 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF572 PF04502.8 CDI85802.1 - 6.5 5.8 14.0 8.1 5.5 9.7 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Bac_luciferase PF00296.15 CDI85802.1 - 6.6 5.7 19.9 7.9 5.4 13.8 1.2 1 0 0 1 1 1 0 Luciferase-like monooxygenase DUF1777 PF08648.7 CDI85802.1 - 6.9 6.3 16.0 15 5.2 11.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1777) TFIIA PF03153.8 CDI85802.1 - 6.9 6.4 26.1 8.9 6.0 18.1 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Herpes_DNAp_acc PF04929.7 CDI85802.1 - 7.3 5.4 12.3 9 5.1 8.5 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor DUF2512 PF10710.4 CDI85802.1 - 7.7 5.9 10.6 11 5.4 7.3 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2512) DUF3450 PF11932.3 CDI85802.1 - 7.9 5.6 22.9 11 5.1 15.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) BAF1_ABF1 PF04684.8 CDI85803.1 - 0.12 11.1 23.3 0.033 13.0 14.0 1.5 1 1 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor SAPS PF04499.10 CDI85803.1 - 0.25 9.9 7.8 0.3 9.6 5.4 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Tetraspannin PF00335.15 CDI85803.1 - 0.27 10.4 4.4 0.38 9.9 3.1 1.1 1 0 0 1 1 1 0 Tetraspanin family Mitofilin PF09731.4 CDI85803.1 - 0.41 9.2 13.5 0.44 9.1 9.4 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Mucin PF01456.12 CDI85803.1 - 2.9 7.6 19.7 4.3 7.1 13.6 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein DUF4638 PF15472.1 CDI85803.1 - 3.1 7.2 6.4 4.6 6.7 4.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) TFIIA PF03153.8 CDI85803.1 - 5.6 6.7 24.2 6.9 6.4 16.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Dscam_C PF12355.3 CDI85803.1 - 6.6 7.0 15.1 0.31 11.3 5.6 2.1 1 1 1 2 2 2 0 Down syndrome cell adhesion molecule C terminal Helicase_C_2 PF13307.1 CDI85804.1 - 1.7e-22 80.1 10.6 1.7e-22 80.1 7.3 3.8 3 2 0 3 3 3 1 Helicase C-terminal domain IncA PF04156.9 CDI85804.1 - 2.5e-05 23.9 2.5 2.5e-05 23.9 1.7 7.0 5 1 1 6 6 6 2 IncA protein DUF4647 PF15504.1 CDI85804.1 - 0.00055 18.9 12.7 0.00055 18.9 8.8 4.1 4 0 0 4 4 4 2 Domain of unknown function (DUF4647) BRF1 PF07741.8 CDI85804.1 - 0.0092 16.1 10.2 0.0092 16.1 7.1 5.8 4 1 1 5 5 5 2 Brf1-like TBP-binding domain AAA_11 PF13086.1 CDI85804.1 - 0.046 13.2 33.4 0.17 11.4 0.1 3.4 3 1 0 3 3 3 0 AAA domain FLO_LFY PF01698.11 CDI85804.1 - 0.26 10.0 33.6 0.095 11.5 4.0 4.1 4 0 0 4 4 4 0 Floricaula / Leafy protein Band_3_cyto PF07565.8 CDI85804.1 - 2.1 7.7 48.6 1.4 8.3 0.2 4.2 4 0 0 4 4 4 0 Band 3 cytoplasmic domain Adaptin_binding PF10199.4 CDI85804.1 - 8.3 6.6 41.8 28 4.9 0.2 3.7 2 1 0 2 2 2 0 Alpha and gamma adaptin binding protein p34 DUF4569 PF15133.1 CDI85805.1 - 3.8 6.8 31.9 4.3 6.6 22.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4569) DUF2489 PF10675.4 CDI85805.1 - 4.3 7.0 33.2 0.92 9.1 8.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2489) DUF4207 PF13904.1 CDI85805.1 - 5.3 6.3 44.4 7.7 5.8 30.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4207) FAM60A PF15396.1 CDI85805.1 - 6.7 6.4 28.4 7 6.3 19.7 1.0 1 0 0 1 1 1 0 Protein Family FAM60A Pox_RNA_Pol_19 PF05320.7 CDI85807.1 - 0.68 9.6 12.5 0.87 9.3 8.7 1.2 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit Zip PF02535.17 CDI85807.1 - 1 8.3 22.3 1.5 7.7 15.5 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter NPR3 PF03666.8 CDI85807.1 - 1.4 7.3 29.7 1.5 7.2 20.6 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Plasmodium_Vir PF05795.6 CDI85807.1 - 2 7.5 10.1 3 6.9 7.0 1.3 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Raftlin PF15250.1 CDI85807.1 - 2.9 6.3 30.7 3 6.2 21.3 1.0 1 0 0 1 1 1 0 Raftlin FAM60A PF15396.1 CDI85807.1 - 5.9 6.5 29.5 5.9 6.5 20.4 1.0 1 0 0 1 1 1 0 Protein Family FAM60A DUF1980 PF09323.5 CDI85809.1 - 0.00033 20.4 5.7 0.00034 20.3 4.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1980) SpoIIIAH PF12685.2 CDI85809.1 - 0.00082 18.9 4.0 0.00087 18.8 2.8 1.0 1 0 0 1 1 1 1 SpoIIIAH-like protein FHIPEP PF00771.15 CDI85809.1 - 0.0016 16.9 3.5 0.0017 16.7 2.4 1.0 1 0 0 1 1 1 1 FHIPEP family DUF788 PF05620.6 CDI85809.1 - 0.0022 17.8 4.4 0.0029 17.4 3.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF788) CD20 PF04103.10 CDI85809.1 - 0.005 16.7 1.0 0.0051 16.7 0.7 1.1 1 0 0 1 1 1 1 CD20-like family Oleosin PF01277.12 CDI85809.1 - 0.016 14.7 1.6 0.019 14.5 1.1 1.2 1 0 0 1 1 1 0 Oleosin ERF PF04404.7 CDI85809.1 - 0.017 14.6 12.3 0.018 14.5 8.5 1.2 1 0 0 1 1 1 0 ERF superfamily TRAP_alpha PF03896.11 CDI85809.1 - 0.021 13.8 1.6 0.022 13.7 1.1 1.0 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit RskA PF10099.4 CDI85809.1 - 0.022 14.4 5.2 0.028 14.1 3.6 1.2 1 0 0 1 1 1 0 Anti-sigma-K factor rskA DUF4557 PF15101.1 CDI85809.1 - 0.025 14.4 15.0 0.026 14.3 10.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) Herpes_glycop PF01528.11 CDI85809.1 - 0.033 12.8 1.5 0.036 12.7 1.0 1.1 1 0 0 1 1 1 0 Herpesvirus glycoprotein M HNOBA PF07701.9 CDI85809.1 - 0.04 13.1 5.9 0.042 13.0 4.1 1.1 1 0 0 1 1 1 0 Heme NO binding associated Serinc PF03348.10 CDI85809.1 - 0.041 12.6 7.1 0.049 12.3 4.9 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) FAM176 PF14851.1 CDI85809.1 - 0.041 13.5 1.2 0.048 13.3 0.9 1.2 1 0 0 1 1 1 0 FAM176 family Ctr PF04145.10 CDI85809.1 - 0.053 13.5 2.0 0.061 13.3 1.4 1.2 1 0 0 1 1 1 0 Ctr copper transporter family Ycf1 PF05758.7 CDI85809.1 - 0.054 11.2 5.6 0.052 11.2 3.9 1.0 1 0 0 1 1 1 0 Ycf1 ATG22 PF11700.3 CDI85809.1 - 0.062 11.7 0.7 0.068 11.6 0.5 1.0 1 0 0 1 1 1 0 Vacuole effluxer Atg22 like TMEM154 PF15102.1 CDI85809.1 - 0.077 12.6 7.6 0.13 11.9 5.2 1.4 1 1 0 1 1 1 0 TMEM154 protein family Peptidase_S49_N PF08496.5 CDI85809.1 - 0.083 12.6 6.5 0.085 12.6 4.5 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal FimP PF09766.4 CDI85809.1 - 0.089 11.8 20.0 0.088 11.8 13.8 1.0 1 0 0 1 1 1 0 Fms-interacting protein YfhO PF09586.5 CDI85809.1 - 0.089 10.7 5.1 0.092 10.7 3.6 1.0 1 0 0 1 1 1 0 Bacterial membrane protein YfhO DUF3260 PF11658.3 CDI85809.1 - 0.1 10.7 6.7 0.097 10.8 4.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3260) Trp_oprn_chp PF09534.5 CDI85809.1 - 0.12 11.9 0.6 0.13 11.8 0.4 1.1 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) OATP PF03137.15 CDI85809.1 - 0.19 9.7 4.8 0.19 9.7 3.3 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Folate_carrier PF01770.13 CDI85809.1 - 0.19 10.1 4.1 0.19 10.2 2.8 1.1 1 0 0 1 1 1 0 Reduced folate carrier IncA PF04156.9 CDI85809.1 - 0.21 11.1 19.0 0.27 10.7 13.2 1.2 1 0 0 1 1 1 0 IncA protein Pex14_N PF04695.8 CDI85809.1 - 0.23 11.4 12.6 0.23 11.5 8.7 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region TMEM51 PF15345.1 CDI85809.1 - 0.24 11.0 9.2 0.24 11.0 6.4 1.2 1 0 0 1 1 1 0 Transmembrane protein 51 DUF3533 PF12051.3 CDI85809.1 - 0.27 9.9 3.3 0.27 9.9 2.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3533) Gti1_Pac2 PF09729.4 CDI85809.1 - 0.28 11.0 5.9 0.31 10.9 4.1 1.0 1 0 0 1 1 1 0 Gti1/Pac2 family 7tm_1 PF00001.16 CDI85809.1 - 0.37 9.8 1.3 0.42 9.7 0.9 1.3 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) Eapp_C PF10238.4 CDI85809.1 - 0.39 10.6 9.1 0.43 10.4 6.3 1.0 1 0 0 1 1 1 0 E2F-associated phosphoprotein Gastrin PF00918.12 CDI85809.1 - 0.42 11.4 12.1 0.44 11.3 8.4 1.1 1 0 0 1 1 1 0 Gastrin/cholecystokinin family R_equi_Vir PF05526.6 CDI85809.1 - 0.43 10.1 3.9 0.45 10.1 2.7 1.0 1 0 0 1 1 1 0 Rhodococcus equi virulence-associated protein DUF2722 PF10846.3 CDI85809.1 - 0.43 9.5 14.9 0.49 9.3 10.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Mem_trans PF03547.13 CDI85809.1 - 0.44 8.7 2.5 0.45 8.7 1.7 1.1 1 0 0 1 1 1 0 Membrane transport protein SID-1_RNA_chan PF13965.1 CDI85809.1 - 0.49 8.5 4.1 0.48 8.5 2.8 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 eIF_4EBP PF05456.6 CDI85809.1 - 0.51 10.0 5.7 0.56 9.9 4.0 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) PH_4 PF15404.1 CDI85809.1 - 0.59 9.6 8.8 0.61 9.5 6.1 1.0 1 0 0 1 1 1 0 Pleckstrin homology domain ABC2_membrane_2 PF12679.2 CDI85809.1 - 0.59 8.9 3.3 0.73 8.6 2.3 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF2422 PF10337.4 CDI85809.1 - 0.79 8.4 10.6 0.9 8.2 7.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2422) CagX PF03524.10 CDI85809.1 - 0.81 8.9 9.6 0.84 8.8 6.7 1.1 1 0 0 1 1 1 0 Conjugal transfer protein Paramyxo_ncap PF00973.14 CDI85809.1 - 0.83 8.2 5.9 0.79 8.3 4.1 1.2 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein DUF3464 PF11947.3 CDI85809.1 - 0.92 8.9 5.8 0.89 8.9 4.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) Band_3_cyto PF07565.8 CDI85809.1 - 0.96 8.9 8.9 0.92 8.9 6.2 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain UPF0560 PF10577.4 CDI85809.1 - 1 7.5 15.3 1 7.5 10.6 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Afi1 PF07792.7 CDI85809.1 - 1.1 9.2 12.2 1.3 9.0 8.5 1.1 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Pex16 PF08610.5 CDI85809.1 - 1.2 8.0 10.2 1.4 7.8 7.1 1.0 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) DUF106 PF01956.11 CDI85809.1 - 1.9 7.9 7.5 2.1 7.8 5.2 1.1 1 0 0 1 1 1 0 Integral membrane protein DUF106 AIF_C PF14721.1 CDI85809.1 - 2.1 8.5 8.1 2.1 8.5 5.6 1.1 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term DDHD PF02862.12 CDI85809.1 - 2.2 8.0 8.4 2.2 8.0 5.8 1.1 1 0 0 1 1 1 0 DDHD domain PAT1 PF09770.4 CDI85809.1 - 2.4 6.2 26.0 2.3 6.3 18.0 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 G0-G1_switch_2 PF15103.1 CDI85809.1 - 2.8 8.1 7.9 3 8.1 5.5 1.2 1 0 0 1 1 1 0 G0/G1 switch protein 2 DUF1418 PF07214.7 CDI85809.1 - 3.3 7.4 6.1 7.1 6.3 4.2 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1418) Prog_receptor PF02161.10 CDI85809.1 - 4 6.1 8.5 4.4 6.0 5.9 1.0 1 0 0 1 1 1 0 Progesterone receptor CHD5 PF04420.9 CDI85809.1 - 4.7 6.8 8.8 5.8 6.5 6.1 1.2 1 0 0 1 1 1 0 CHD5-like protein Suf PF05843.9 CDI85809.1 - 4.8 6.8 18.0 4.8 6.8 12.5 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF2946 PF11162.3 CDI85809.1 - 4.9 7.3 8.1 6.4 7.0 5.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2946) Pex26 PF07163.7 CDI85809.1 - 5.2 5.8 9.4 6.5 5.5 6.5 1.2 1 0 0 1 1 1 0 Pex26 protein EphA2_TM PF14575.1 CDI85809.1 - 6.5 7.2 10.7 14 6.1 7.4 1.8 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF3357 PF11837.3 CDI85809.1 - 6.9 6.5 7.6 18 5.1 5.2 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF3357) DivIC PF04977.10 CDI85809.1 - 7.5 6.1 22.4 12 5.4 15.5 1.3 1 0 0 1 1 1 0 Septum formation initiator DUF3276 PF11680.3 CDI85809.1 - 7.8 6.3 9.7 8.5 6.2 6.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3276) 7tm_7 PF08395.7 CDI85809.1 - 8.1 5.3 8.3 8.4 5.2 5.8 1.1 1 0 0 1 1 1 0 7tm Chemosensory receptor 7TM_GPCR_Srx PF10328.4 CDI85809.1 - 8.6 5.3 7.6 10 5.1 5.3 1.2 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srx SprA-related PF12118.3 CDI85809.1 - 9.1 5.5 28.1 8.9 5.5 19.5 1.1 1 0 0 1 1 1 0 SprA-related family DNA_pol3_a_NII PF11490.3 CDI85809.1 - 9.8 5.8 22.5 11 5.6 15.6 1.1 1 0 0 1 1 1 0 DNA polymerase III polC-type N-terminus II PALP PF00291.20 CDI85814.1 - 5.3e-49 167.0 0.9 1.2e-48 165.9 0.6 1.6 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CBS PF00571.23 CDI85814.1 - 0.0066 16.2 0.1 0.72 9.6 0.0 3.2 3 0 0 3 3 3 1 CBS domain CDK2AP PF09806.4 CDI85816.1 - 0.00063 20.0 0.5 0.00074 19.7 0.4 1.1 1 0 0 1 1 1 1 Cyclin-dependent kinase 2-associated protein Luteo_P1-P2 PF08467.5 CDI85816.1 - 0.17 10.6 0.0 0.22 10.3 0.0 1.1 1 0 0 1 1 1 0 Luteovirus RNA polymerase P1-P2/replicase DUF1183 PF06682.7 CDI85817.1 - 0.077 12.5 5.8 0.14 11.7 4.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1183) Spt20 PF12090.3 CDI85817.1 - 0.3 10.4 9.5 0.76 9.0 0.2 2.1 2 0 0 2 2 2 0 Spt20 family PAT1 PF09770.4 CDI85817.1 - 0.38 8.9 21.2 0.45 8.7 14.7 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 RAB3GAP2_N PF14655.1 CDI85817.1 - 5.4 5.9 10.2 2.6 6.9 0.2 2.1 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus FimP PF09766.4 CDI85817.1 - 7.5 5.5 13.7 7.1 5.5 0.6 2.1 2 0 0 2 2 2 0 Fms-interacting protein Phostensin_N PF13916.1 CDI85817.1 - 8.6 6.4 15.7 1.7 8.7 1.9 2.7 2 0 0 2 2 2 0 PP1-regulatory protein, Phostensin N-terminal RCC1 PF00415.13 CDI85818.1 - 1.2e-23 82.9 29.2 1.9e-07 31.1 0.5 8.6 8 1 0 8 8 8 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 CDI85818.1 - 6.7e-23 79.7 39.4 1.4e-07 30.9 2.6 6.9 7 0 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat Spt20 PF12090.3 CDI85818.1 - 0.043 13.1 9.1 1 8.7 0.5 3.3 3 0 0 3 3 3 0 Spt20 family CBM_X PF06204.6 CDI85818.1 - 0.33 10.4 1.9 7.1 6.2 0.1 3.3 4 0 0 4 4 4 0 Putative carbohydrate binding domain LRR_4 PF12799.2 CDI85821.1 - 2.6e-38 129.0 39.4 4.5e-10 38.9 1.9 5.9 2 2 6 8 8 8 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CDI85821.1 - 1.5e-25 88.6 23.3 1.5e-10 40.6 0.5 4.5 2 2 2 5 5 5 4 Leucine rich repeat LRR_1 PF00560.28 CDI85821.1 - 4.9e-13 47.1 26.0 0.08 13.0 0.1 8.7 8 1 1 9 9 9 5 Leucine Rich Repeat LRR_6 PF13516.1 CDI85821.1 - 5.5e-11 41.3 19.2 0.11 12.6 0.2 8.1 5 1 2 7 7 7 5 Leucine Rich repeat LRR_7 PF13504.1 CDI85821.1 - 2.5e-10 38.7 17.5 0.7 10.3 0.2 8.7 7 2 2 9 9 9 4 Leucine rich repeat LRR_9 PF14580.1 CDI85821.1 - 1.1e-08 34.8 10.4 6.8e-05 22.4 1.0 3.1 1 1 2 3 3 3 2 Leucine-rich repeat DUF2322 PF10084.4 CDI85821.1 - 0.2 11.3 1.2 2.4 7.9 0.2 2.7 2 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2322) IER PF05760.7 CDI85823.1 - 0.44 10.4 10.0 0.51 10.2 6.9 1.0 1 0 0 1 1 1 0 Immediate early response protein (IER) Rifin_STEVOR PF02009.11 CDI85823.1 - 0.77 9.3 6.3 1.1 8.7 4.4 1.3 1 0 0 1 1 1 0 Rifin/stevor family Med3 PF11593.3 CDI85823.1 - 1.8 7.7 25.2 2.2 7.4 17.4 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Trs65 PF12735.2 CDI85824.1 - 0.19 11.0 6.0 0.18 11.1 4.2 1.1 1 0 0 1 1 1 0 TRAPP trafficking subunit Trs65 DUF4367 PF14285.1 CDI85824.1 - 0.25 10.6 3.7 0.28 10.4 2.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4367) Shadoo PF14999.1 CDI85824.1 - 0.32 10.8 19.3 0.53 10.1 13.4 1.4 1 1 0 1 1 1 0 Shadow of prion protein, neuroprotective DUF3617 PF12276.3 CDI85824.1 - 0.84 9.0 12.1 1 8.8 8.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3617) RskA PF10099.4 CDI85824.1 - 0.92 9.2 14.8 1.1 8.9 10.2 1.1 1 0 0 1 1 1 0 Anti-sigma-K factor rskA Ctr PF04145.10 CDI85824.1 - 3 7.8 6.4 3.2 7.7 4.4 1.1 1 0 0 1 1 1 0 Ctr copper transporter family DUF106 PF01956.11 CDI85824.1 - 6.2 6.3 6.0 6.8 6.1 4.1 1.1 1 0 0 1 1 1 0 Integral membrane protein DUF106 DUF2217 PF10265.4 CDI85824.1 - 6.7 5.3 9.8 6.7 5.3 6.8 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) SpaB_C PF14028.1 CDI85824.1 - 9.2 5.7 11.8 9.7 5.6 8.2 1.0 1 0 0 1 1 1 0 SpaB C-terminal domain DUF4557 PF15101.1 CDI85824.1 - 9.9 5.9 15.8 11 5.8 10.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) DUF3530 PF12048.3 CDI85825.1 - 0.012 14.5 4.5 0.012 14.5 3.1 4.1 2 1 2 4 4 4 0 Protein of unknown function (DUF3530) COPI_assoc PF08507.5 CDI85825.1 - 0.035 13.7 0.1 0.035 13.7 0.1 3.9 2 1 1 3 3 3 0 COPI associated protein DUF3188 PF11384.3 CDI85825.1 - 1.3 8.6 3.8 2.3 7.8 0.3 3.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3188) Vps51 PF08700.6 CDI85826.1 - 0.096 12.5 7.5 0.12 12.1 5.2 1.2 1 0 0 1 1 1 0 Vps51/Vps67 Suc_Fer-like PF06999.7 CDI85826.1 - 0.1 12.6 0.4 0.12 12.3 0.3 1.0 1 0 0 1 1 1 0 Sucrase/ferredoxin-like Med15 PF09606.5 CDI85826.1 - 0.17 10.0 20.9 0.17 10.0 14.5 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal PAT1 PF09770.4 CDI85826.1 - 0.56 8.3 13.2 0.62 8.2 9.2 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF3365 PF11845.3 CDI85826.1 - 0.93 9.3 4.6 1 9.1 3.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3365) FAM222A PF15258.1 CDI85826.1 - 5.1 6.1 11.5 5.1 6.2 8.0 1.1 1 0 0 1 1 1 0 Protein family of FAM222A BAF1_ABF1 PF04684.8 CDI85826.1 - 6.1 5.5 9.9 6.8 5.4 6.8 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor OTT_1508_deam PF14441.1 CDI85827.1 - 0.076 12.8 4.8 0.14 11.9 3.3 1.4 1 0 0 1 1 1 0 OTT_1508-like deaminase Plasmodium_Vir PF05795.6 CDI85827.1 - 7.9 5.5 5.7 11 5.1 3.9 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein DUF4657 PF15552.1 CDI85829.1 - 0.0064 15.8 0.4 0.0065 15.8 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4657) PIN_3 PF13470.1 CDI85829.1 - 0.073 13.7 0.3 0.11 13.1 0.2 1.3 1 0 0 1 1 1 0 PIN domain Med15 PF09606.5 CDI85830.1 - 3.5 5.7 11.3 4.1 5.4 7.8 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF1510 PF07423.6 CDI85831.1 - 0.0088 15.4 14.0 0.012 15.0 9.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) MRP-S31 PF15433.1 CDI85831.1 - 0.075 12.4 14.0 0.13 11.6 9.7 1.3 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 Mem_trans PF03547.13 CDI85831.1 - 0.16 10.2 3.6 0.24 9.6 2.5 1.3 1 0 0 1 1 1 0 Membrane transport protein DUF2512 PF10710.4 CDI85831.1 - 0.16 11.3 0.0 0.16 11.3 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2512) Ycf1 PF05758.7 CDI85831.1 - 0.17 9.5 8.3 0.18 9.4 5.7 1.0 1 0 0 1 1 1 0 Ycf1 DUF572 PF04502.8 CDI85831.1 - 0.18 10.9 18.2 0.21 10.7 12.6 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF4045 PF13254.1 CDI85831.1 - 0.2 10.9 15.6 0.24 10.6 10.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) PLRV_ORF5 PF01690.12 CDI85831.1 - 0.27 10.3 15.0 0.31 10.1 10.4 1.0 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein DNA_pol_viral_N PF00242.12 CDI85831.1 - 0.43 9.5 15.1 0.5 9.3 10.5 1.1 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain DRY_EERY PF09750.4 CDI85831.1 - 0.44 10.6 16.5 0.035 14.1 7.8 1.7 2 0 0 2 2 2 0 Alternative splicing regulator DUF3357 PF11837.3 CDI85831.1 - 0.45 10.3 12.0 1.3 8.8 4.5 2.4 1 1 0 2 2 2 0 Domain of unknown function (DUF3357) RskA PF10099.4 CDI85831.1 - 0.57 9.9 27.3 0.62 9.7 11.8 2.1 1 1 1 2 2 2 0 Anti-sigma-K factor rskA Macoilin PF09726.4 CDI85831.1 - 0.75 7.9 13.3 0.93 7.6 9.2 1.1 1 0 0 1 1 1 0 Transmembrane protein SRP-alpha_N PF04086.8 CDI85831.1 - 0.83 8.9 17.2 1.1 8.6 11.9 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal eIF-3_zeta PF05091.7 CDI85831.1 - 1 7.9 16.3 1.2 7.6 11.3 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF2637 PF10935.3 CDI85831.1 - 1.2 9.0 11.1 0.39 10.6 3.1 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2637) SGT1 PF07093.6 CDI85831.1 - 1.2 7.3 14.8 1.8 6.8 10.3 1.2 1 0 0 1 1 1 0 SGT1 protein DUF966 PF06136.8 CDI85831.1 - 1.3 8.3 17.4 1.6 8.0 12.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF966) GAGA_bind PF06217.7 CDI85831.1 - 1.3 8.9 11.2 1.6 8.6 7.7 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family PIH1 PF08190.7 CDI85831.1 - 1.5 8.1 16.9 2 7.8 11.7 1.1 1 0 0 1 1 1 0 pre-RNA processing PIH1/Nop17 DUF4175 PF13779.1 CDI85831.1 - 2 6.0 37.5 2.5 5.6 26.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) PAT1 PF09770.4 CDI85831.1 - 2 6.5 32.9 2.4 6.3 22.8 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Asp-B-Hydro_N PF05279.6 CDI85831.1 - 2.5 7.9 14.2 3.1 7.5 9.9 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region DUF2615 PF11027.3 CDI85831.1 - 3 7.8 9.2 0.75 9.7 1.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2615) SPX PF03105.14 CDI85831.1 - 3.3 7.3 15.4 4.8 6.8 10.7 1.2 1 0 0 1 1 1 0 SPX domain SAPS PF04499.10 CDI85831.1 - 3.4 6.1 12.7 4.6 5.7 8.8 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein SOBP PF15279.1 CDI85831.1 - 4.5 7.5 12.3 5.8 7.2 8.5 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein Zip PF02535.17 CDI85831.1 - 4.8 6.0 5.3 5.2 5.9 3.1 1.5 1 1 0 1 1 1 0 ZIP Zinc transporter Ndc1_Nup PF09531.5 CDI85831.1 - 5.4 5.3 16.2 6.6 5.0 11.2 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF45 PF01863.12 CDI85831.1 - 6.2 6.5 9.3 7.5 6.2 6.5 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF45 FemAB PF02388.11 CDI85831.1 - 6.3 5.3 13.2 7.2 5.1 9.1 1.1 1 0 0 1 1 1 0 FemAB family Peptidase_S64 PF08192.6 CDI85831.1 - 7.1 4.8 14.9 9.1 4.4 10.3 1.0 1 0 0 1 1 1 0 Peptidase family S64 Hid1 PF12722.2 CDI85831.1 - 7.3 4.1 18.8 9 3.8 13.1 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Sporozoite_P67 PF05642.6 CDI85831.1 - 7.6 4.2 13.1 9.2 3.9 9.1 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen TMEM51 PF15345.1 CDI85831.1 - 8.7 5.9 18.8 12 5.5 13.0 1.2 1 0 0 1 1 1 0 Transmembrane protein 51 DUF4512 PF14975.1 CDI85832.1 - 1.1 10.1 6.2 1.2 9.9 4.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4512) FHIPEP PF00771.15 CDI85832.1 - 1.1 7.4 7.0 1.5 7.0 4.8 1.2 1 0 0 1 1 1 0 FHIPEP family DUF3474 PF11960.3 CDI85832.1 - 1.1 9.2 3.6 1.4 8.9 2.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3474) DUF4045 PF13254.1 CDI85832.1 - 1.4 8.0 12.7 1.5 8.0 8.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) PMSI1 PF15322.1 CDI85832.1 - 1.8 7.5 10.3 2 7.4 7.1 1.0 1 0 0 1 1 1 0 Protein missing in infertile sperm 1, putative LAM_C PF12544.3 CDI85832.1 - 1.9 8.5 6.5 2.3 8.2 4.5 1.1 1 0 0 1 1 1 0 Lysine-2,3-aminomutase Herpes_DNAp_acc PF04929.7 CDI85832.1 - 2 7.2 15.2 2.2 7.1 10.6 1.0 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Presenilin PF01080.12 CDI85832.1 - 2.8 6.6 9.9 2.9 6.6 6.9 1.0 1 0 0 1 1 1 0 Presenilin DUF4446 PF14584.1 CDI85832.1 - 4.6 7.0 9.3 5.2 6.8 6.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) DUF4011 PF13195.1 CDI85832.1 - 4.8 7.1 10.5 5.3 7.0 7.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4011) Nuc_deoxyrib_tr PF05014.10 CDI85832.1 - 6.5 6.6 7.6 8.1 6.3 5.3 1.1 1 0 0 1 1 1 0 Nucleoside 2-deoxyribosyltransferase DDHD PF02862.12 CDI85832.1 - 6.6 6.4 12.4 7.5 6.2 8.6 1.1 1 0 0 1 1 1 0 DDHD domain GBP_C PF02841.9 CDI85832.1 - 7.4 5.6 25.6 8.5 5.4 17.8 1.0 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain FAM60A PF15396.1 CDI85832.1 - 7.4 6.2 11.2 7.8 6.1 7.7 1.0 1 0 0 1 1 1 0 Protein Family FAM60A AUX_IAA PF02309.11 CDI85832.1 - 8.2 6.1 10.7 8.8 6.0 7.4 1.1 1 0 0 1 1 1 0 AUX/IAA family Serinc PF03348.10 CDI85832.1 - 8.6 4.9 11.8 9.7 4.7 8.2 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) KASH PF10541.4 CDI85833.1 - 0.12 12.2 2.9 0.23 11.3 2.0 1.5 1 0 0 1 1 1 0 Nuclear envelope localisation domain VIT1 PF01988.14 CDI85834.1 - 0.0025 17.3 6.4 0.0025 17.3 4.4 2.1 3 0 0 3 3 3 1 VIT family Sigma_reg_C PF13791.1 CDI85834.1 - 0.03 14.3 1.9 0.051 13.6 0.3 2.0 2 0 0 2 2 2 0 Sigma factor regulator C-terminal Bacteriocin_IIc PF10439.4 CDI85834.1 - 0.27 11.3 19.4 0.56 10.3 13.1 1.7 2 0 0 2 2 2 0 Bacteriocin class II with double-glycine leader peptide Acetate_kinase PF00871.12 CDI85834.1 - 2.6 6.4 5.1 8.7 4.7 0.1 2.1 2 0 0 2 2 2 0 Acetokinase family RAB3GAP2_N PF14655.1 CDI85834.1 - 6.1 5.7 23.1 0.32 9.9 1.5 3.1 3 0 0 3 3 3 0 Rab3 GTPase-activating protein regulatory subunit N-terminus RAP1 PF07218.6 CDI85835.1 - 0.55 8.2 15.6 0.01 13.9 5.5 2.2 2 0 0 2 2 2 0 Rhoptry-associated protein 1 (RAP-1) DUF2981 PF11200.3 CDI85835.1 - 1.6 7.7 8.6 3.1 6.7 6.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) SRCR PF00530.13 CDI85836.1 - 0.022 15.0 0.0 11 6.4 0.0 2.6 1 1 1 2 2 2 0 Scavenger receptor cysteine-rich domain DUF2477 PF10631.4 CDI85836.1 - 0.086 13.0 2.1 1.1 9.5 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2477) GKAP PF03359.8 CDI85837.1 - 0.075 12.6 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 Guanylate-kinase-associated protein (GKAP) protein polyprenyl_synt PF00348.12 CDI85839.1 - 6.2e-29 100.6 0.7 4.2e-16 58.5 0.0 3.4 3 0 0 3 3 3 3 Polyprenyl synthetase P12 PF12669.2 CDI85839.1 - 0.027 14.6 0.6 0.027 14.6 0.4 3.5 4 0 0 4 4 4 0 Virus attachment protein p12 family PIG-U PF06728.8 CDI85839.1 - 0.55 9.0 1.6 0.82 8.4 1.1 1.2 1 0 0 1 1 1 0 GPI transamidase subunit PIG-U SHS2_Rpb7-N PF03876.12 CDI85840.1 - 4.3e-13 49.1 0.1 8.1e-13 48.3 0.1 1.4 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.18 CDI85840.1 - 6.4e-06 26.1 0.0 0.00028 20.8 0.0 2.2 2 0 0 2 2 2 1 S1 RNA binding domain PknH_C PF14032.1 CDI85840.1 - 0.0053 16.3 2.3 0.0067 16.0 1.6 1.2 1 0 0 1 1 1 1 PknH-like extracellular domain Surp PF01805.15 CDI85841.1 - 1.3e-05 24.6 2.7 0.00023 20.7 0.1 2.6 2 0 0 2 2 2 2 Surp module LRR_4 PF12799.2 CDI85842.1 - 5.6e-23 80.1 19.8 3.6e-07 29.6 0.0 5.2 4 1 0 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CDI85842.1 - 8.3e-15 54.3 22.9 6.8e-08 32.1 1.2 4.5 1 1 5 6 6 6 6 Leucine rich repeat LRR_1 PF00560.28 CDI85842.1 - 3.8e-11 41.4 19.2 0.1 12.6 0.0 8.3 7 1 1 8 8 8 5 Leucine Rich Repeat LRR_9 PF14580.1 CDI85842.1 - 2.7e-10 40.1 0.2 4.8e-05 23.0 0.7 2.5 1 1 1 2 2 2 2 Leucine-rich repeat LRR_7 PF13504.1 CDI85842.1 - 1.1e-06 27.8 23.7 0.41 11.0 0.0 8.4 6 3 1 7 7 7 3 Leucine rich repeat LRR_6 PF13516.1 CDI85842.1 - 1.2e-05 24.8 19.1 0.14 12.2 0.0 7.3 6 2 1 7 7 7 2 Leucine Rich repeat Ribosomal_S19 PF00203.16 CDI85844.1 - 9.2e-28 95.6 0.0 1.3e-27 95.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 SGS PF05002.10 CDI85845.1 - 2.5e-12 46.3 0.8 5.6e-12 45.2 0.5 1.5 1 0 0 1 1 1 1 SGS domain CS PF04969.11 CDI85845.1 - 7.1e-10 39.2 0.0 1.2e-09 38.6 0.0 1.4 1 0 0 1 1 1 1 CS domain Siah-Interact_N PF09032.6 CDI85845.1 - 2.1e-07 30.8 4.4 4.6e-06 26.5 0.5 2.6 2 0 0 2 2 2 1 Siah interacting protein, N terminal DUF2746 PF10874.3 CDI85845.1 - 0.017 15.2 2.6 0.61 10.3 0.5 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2746) Kinesin-relat_1 PF12711.2 CDI85845.1 - 0.12 12.7 4.9 0.61 10.5 2.3 2.6 2 1 1 3 3 3 0 Kinesin motor Syntaxin-6_N PF09177.6 CDI85845.1 - 0.71 10.3 3.9 1.1 9.7 1.0 2.5 2 1 0 2 2 2 0 Syntaxin 6, N-terminal CUE PF02845.11 CDI85846.1 - 0.034 13.6 0.3 0.15 11.6 0.0 2.2 2 0 0 2 2 2 0 CUE domain DUF4110 PF13422.1 CDI85847.1 - 3e-17 62.2 1.1 3e-17 62.2 0.8 3.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4110) Kelch_4 PF13418.1 CDI85847.1 - 3.3e-17 61.9 0.3 2e-10 40.2 0.0 2.8 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_3 PF13415.1 CDI85847.1 - 3.8e-09 36.4 0.1 2.3e-06 27.6 0.0 3.5 3 0 0 3 3 3 1 Galactose oxidase, central domain Kelch_5 PF13854.1 CDI85847.1 - 1.4e-05 24.9 0.0 0.032 14.2 0.0 2.6 2 0 0 2 2 2 2 Kelch motif Kelch_6 PF13964.1 CDI85847.1 - 5.8e-05 23.0 0.0 0.016 15.3 0.0 2.6 2 0 0 2 2 2 1 Kelch motif Kelch_2 PF07646.10 CDI85847.1 - 0.08 12.7 0.1 0.51 10.1 0.0 2.3 2 0 0 2 2 2 0 Kelch motif Nucleoporin_FG PF13634.1 CDI85850.1 - 3.4e-22 78.7 140.1 2.2e-07 31.1 29.5 4.4 1 1 3 4 4 4 4 Nucleoporin FG repeat region EcoRI_methylase PF13651.1 CDI85853.1 - 0.17 10.9 8.0 0.19 10.7 5.5 1.0 1 0 0 1 1 1 0 Adenine-specific methyltransferase EcoRI PBP1_TM PF14812.1 CDI85853.1 - 0.38 11.0 8.1 0.45 10.8 5.6 1.2 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Pex14_N PF04695.8 CDI85853.1 - 0.83 9.7 26.1 0.92 9.5 18.1 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region CKAP2_C PF15297.1 CDI85853.1 - 1.2 7.8 16.7 1.2 7.8 11.6 1.0 1 0 0 1 1 1 0 Cytoskeleton-associated protein 2 C-terminus SelP_N PF04592.9 CDI85853.1 - 2.1 7.6 18.3 2 7.7 12.7 1.0 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Peptidase_U57 PF05582.7 CDI85853.1 - 2.4 7.0 14.6 2.3 7.1 10.1 1.0 1 0 0 1 1 1 0 YabG peptidase U57 FYDLN_acid PF09538.5 CDI85853.1 - 2.6 8.6 7.5 3 8.4 5.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) Glyco_transf_15 PF01793.11 CDI85853.1 - 2.7 6.8 16.5 2.8 6.8 11.4 1.0 1 0 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase Bud13 PF09736.4 CDI85853.1 - 2.9 8.1 23.2 3.2 7.9 16.1 1.1 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex FAM176 PF14851.1 CDI85853.1 - 3.4 7.3 9.3 4.1 7.0 6.5 1.2 1 0 0 1 1 1 0 FAM176 family PAT1 PF09770.4 CDI85853.1 - 3.8 5.6 44.2 3.7 5.6 30.7 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 AIF_C PF14721.1 CDI85853.1 - 4.1 7.6 15.2 4.4 7.5 10.5 1.1 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Gag_spuma PF03276.9 CDI85853.1 - 4.7 5.4 38.7 4.9 5.3 26.9 1.0 1 0 0 1 1 1 0 Spumavirus gag protein ARF7EP_C PF14949.1 CDI85853.1 - 4.8 7.6 17.0 5.9 7.3 11.8 1.2 1 0 0 1 1 1 0 ARF7 effector protein C-terminus Tim54 PF11711.3 CDI85853.1 - 4.9 5.6 12.7 5.4 5.5 8.8 1.0 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Raftlin PF15250.1 CDI85853.1 - 4.9 5.5 17.0 4.9 5.5 11.8 1.0 1 0 0 1 1 1 0 Raftlin DUF1764 PF08576.5 CDI85853.1 - 4.9 7.9 18.8 7.2 7.4 13.1 1.3 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) DUF4557 PF15101.1 CDI85853.1 - 5.7 6.7 32.3 6.2 6.6 22.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) Pal1 PF08316.6 CDI85853.1 - 5.7 7.3 10.2 6.4 7.2 7.1 1.1 1 0 0 1 1 1 0 Pal1 cell morphology protein FLO_LFY PF01698.11 CDI85853.1 - 6 5.6 17.6 6 5.6 12.2 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein Hid1 PF12722.2 CDI85853.1 - 6.4 4.3 18.7 6.7 4.2 13.0 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein BORG_CEP PF14957.1 CDI85853.1 - 6.8 7.6 11.6 8.5 7.3 8.1 1.2 1 0 0 1 1 1 0 Cdc42 effector FAM60A PF15396.1 CDI85853.1 - 7.4 6.2 14.6 7.4 6.2 10.1 1.1 1 0 0 1 1 1 0 Protein Family FAM60A DUF4175 PF13779.1 CDI85853.1 - 7.6 4.1 53.0 7.4 4.1 36.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Asp-B-Hydro_N PF05279.6 CDI85853.1 - 7.6 6.3 11.8 8.1 6.2 8.2 1.0 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region AUX_IAA PF02309.11 CDI85853.1 - 7.6 6.2 15.0 8.4 6.0 10.4 1.1 1 0 0 1 1 1 0 AUX/IAA family Gti1_Pac2 PF09729.4 CDI85853.1 - 7.7 6.3 15.2 9.1 6.1 10.5 1.1 1 0 0 1 1 1 0 Gti1/Pac2 family Rtf2 PF04641.7 CDI85853.1 - 9.3 5.3 18.5 9.7 5.3 12.8 1.0 1 0 0 1 1 1 0 Rtf2 RING-finger Zip PF02535.17 CDI85853.1 - 9.9 5.0 14.3 11 4.9 9.9 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter DUF3439 PF11921.3 CDI85854.1 - 0.33 10.7 12.2 4.5 7.0 8.2 3.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Neur_chan_memb PF02932.11 CDI85855.1 - 0.085 12.7 0.2 0.076 12.8 0.1 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Tim54 PF11711.3 CDI85855.1 - 0.39 9.2 8.3 0.53 8.8 5.7 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 SprA-related PF12118.3 CDI85856.1 - 0.00044 19.6 7.1 0.00044 19.6 4.9 3.0 2 1 0 2 2 2 1 SprA-related family AAA_23 PF13476.1 CDI85856.1 - 0.0015 18.9 9.0 0.0098 16.2 0.9 2.7 3 0 0 3 3 3 2 AAA domain CD20 PF04103.10 CDI85856.1 - 0.027 14.4 0.6 0.027 14.4 0.4 4.2 4 1 1 5 5 5 0 CD20-like family PAT1 PF09770.4 CDI85856.1 - 0.24 9.6 53.0 0.16 10.1 18.6 2.2 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 Dala_Dala_lig_N PF01820.16 CDI85856.1 - 2.1 8.7 8.4 8.5 6.7 0.1 3.9 4 0 0 4 4 4 0 D-ala D-ala ligase N-terminus zf-DHHC PF01529.15 CDI85856.1 - 9 5.6 13.3 5.8 6.2 0.2 3.7 4 0 0 4 4 4 0 DHHC palmitoyltransferase Macoilin PF09726.4 CDI85857.1 - 7.2 4.7 15.1 11 4.2 10.4 1.3 1 0 0 1 1 1 0 Transmembrane protein Corona_nucleoca PF00937.13 CDI85857.1 - 7.8 5.3 11.4 14 4.5 7.9 1.4 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein Dala_Dala_lig_N PF01820.16 CDI85858.1 - 1.5 9.1 7.6 1.7 8.9 5.3 1.1 1 0 0 1 1 1 0 D-ala D-ala ligase N-terminus Ldh_1_C PF02866.13 CDI85860.1 - 6.7e-21 74.7 0.0 6.8e-16 58.4 0.0 2.0 1 1 1 2 2 2 2 lactate/malate dehydrogenase, alpha/beta C-terminal domain Sigma70_r3 PF04539.11 CDI85860.1 - 0.13 12.1 0.8 1.1 9.1 0.0 2.1 2 0 0 2 2 2 0 Sigma-70 region 3 SSP160 PF06933.6 CDI85861.1 - 2.2 6.1 21.0 3.6 5.4 14.6 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 MIF PF01187.13 CDI85862.1 - 6.3e-15 55.2 0.1 6.4e-15 55.2 0.0 1.0 1 0 0 1 1 1 1 Macrophage migration inhibitory factor (MIF) RYDR_ITPR PF01365.16 CDI85862.1 - 0.01 15.0 0.1 0.012 14.8 0.1 1.1 1 0 0 1 1 1 0 RIH domain Potassium_chann PF11404.3 CDI85862.1 - 0.26 11.1 1.1 0.56 10.0 0.8 1.6 1 0 0 1 1 1 0 Potassium voltage-gated channel Radial_spoke_3 PF06098.6 CDI85863.1 - 5.8e-11 41.9 1.8 8.4e-08 31.5 0.0 2.4 1 1 1 2 2 2 2 Radial spoke protein 3 SR-25 PF10500.4 CDI85863.1 - 0.018 14.5 1.1 0.019 14.4 0.8 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein TctA PF01970.11 CDI85863.1 - 0.71 8.2 3.7 0.93 7.8 2.6 1.1 1 0 0 1 1 1 0 Tripartite tricarboxylate transporter TctA family ETRAMP PF09716.5 CDI85863.1 - 1.5 8.8 3.6 9.7 6.2 2.5 2.1 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) TFIIA PF03153.8 CDI85863.1 - 6.4 6.5 9.3 7.4 6.3 6.5 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CMV_1a PF12467.3 CDI85864.1 - 1.1 9.5 5.9 2.5 8.4 4.1 1.5 1 0 0 1 1 1 0 Cucumber mosaic virus 1a protein family DUF3573 PF12097.3 CDI85864.1 - 1.2 7.6 2.9 2.3 6.7 2.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) VHS PF00790.14 CDI85865.1 - 0.066 12.8 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 VHS domain IncA PF04156.9 CDI85866.1 - 0.0018 17.9 49.9 0.0035 16.9 34.6 1.5 1 0 0 1 1 1 1 IncA protein V_ATPase_I PF01496.14 CDI85866.1 - 0.061 11.1 26.8 0.087 10.6 18.6 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family PA26 PF04636.8 CDI85866.1 - 0.17 10.5 15.6 0.25 10.0 10.8 1.2 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) APG6 PF04111.7 CDI85866.1 - 0.21 10.5 46.3 0.3 10.0 32.1 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Atg14 PF10186.4 CDI85866.1 - 0.22 10.4 38.0 0.3 9.9 26.4 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Spc7 PF08317.6 CDI85866.1 - 1.3 7.6 37.4 2 6.9 25.9 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein Fmp27_WPPW PF10359.4 CDI85866.1 - 1.9 6.8 28.6 2.7 6.3 19.8 1.2 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain WXG100 PF06013.7 CDI85866.1 - 2.5 8.1 53.2 1.6 8.8 10.2 3.6 2 1 2 4 4 4 0 Proteins of 100 residues with WXG GAGA_bind PF06217.7 CDI85866.1 - 3.2 7.6 19.4 4.6 7.1 13.5 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family HSP70 PF00012.15 CDI85866.1 - 3.5 5.4 15.6 4.4 5.0 10.8 1.1 1 0 0 1 1 1 0 Hsp70 protein DUF4045 PF13254.1 CDI85866.1 - 6.4 5.9 16.1 11 5.1 11.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) DUF3552 PF12072.3 CDI85866.1 - 6.7 5.8 51.5 5.7 6.0 20.7 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3552) Hid1 PF12722.2 CDI85868.1 - 1.6 6.3 36.6 1.9 6.0 25.4 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein IncA PF04156.9 CDI85869.1 - 0.0023 17.5 20.7 0.0032 17.0 14.3 1.4 1 0 0 1 1 1 1 IncA protein MIP-T3 PF10243.4 CDI85869.1 - 0.019 13.4 31.9 0.027 12.9 22.1 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Daxx PF03344.10 CDI85869.1 - 0.029 12.8 26.0 0.032 12.7 18.0 1.0 1 0 0 1 1 1 0 Daxx Family DUF3987 PF13148.1 CDI85869.1 - 0.042 12.4 15.2 0.046 12.2 10.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) Med15 PF09606.5 CDI85869.1 - 0.043 12.0 55.1 0.049 11.8 38.2 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Plasmodium_Vir PF05795.6 CDI85869.1 - 0.053 12.7 13.7 0.082 12.0 9.5 1.3 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Ycf1 PF05758.7 CDI85869.1 - 0.075 10.7 23.4 0.089 10.5 16.3 1.1 1 0 0 1 1 1 0 Ycf1 DDRGK PF09756.4 CDI85869.1 - 0.11 11.8 31.1 0.14 11.5 21.5 1.2 1 0 0 1 1 1 0 DDRGK domain eIF-3_zeta PF05091.7 CDI85869.1 - 0.13 10.8 24.3 0.16 10.6 16.8 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Spc7_N PF15402.1 CDI85869.1 - 0.15 10.0 33.3 0.19 9.6 23.1 1.0 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 TRAP_alpha PF03896.11 CDI85869.1 - 0.19 10.6 9.6 0.23 10.4 6.6 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Tim54 PF11711.3 CDI85869.1 - 0.2 10.2 19.6 0.25 9.9 13.6 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DUF4045 PF13254.1 CDI85869.1 - 0.35 10.1 27.8 0.49 9.6 19.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) BTV_NS2 PF04514.7 CDI85869.1 - 0.47 9.2 18.0 0.51 9.1 12.5 1.2 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 CoA_transf_3 PF02515.12 CDI85869.1 - 0.5 9.5 7.6 0.67 9.1 5.3 1.2 1 0 0 1 1 1 0 CoA-transferase family III Peptidase_S15 PF02129.13 CDI85869.1 - 0.5 9.7 14.9 0.61 9.4 10.3 1.1 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) DUF572 PF04502.8 CDI85869.1 - 0.62 9.2 31.8 0.77 8.9 22.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) DNA_pol_viral_N PF00242.12 CDI85869.1 - 0.94 8.4 30.7 1.1 8.2 21.3 1.0 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain DUF3402 PF11882.3 CDI85869.1 - 1.3 7.9 21.0 1.6 7.6 14.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3402) GBP_C PF02841.9 CDI85869.1 - 1.3 8.1 36.5 1.7 7.7 25.3 1.1 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain Na_trans_assoc PF06512.8 CDI85869.1 - 1.3 8.9 22.6 1.8 8.4 15.7 1.1 1 0 0 1 1 1 0 Sodium ion transport-associated Asp-B-Hydro_N PF05279.6 CDI85869.1 - 1.5 8.5 22.1 1.9 8.3 15.3 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Macoilin PF09726.4 CDI85869.1 - 1.6 6.8 32.7 2 6.5 22.7 1.0 1 0 0 1 1 1 0 Transmembrane protein Parvo_coat PF00740.13 CDI85869.1 - 1.8 7.3 30.3 2.1 7.1 21.0 1.0 1 0 0 1 1 1 0 Parvovirus coat protein VP2 PLRV_ORF5 PF01690.12 CDI85869.1 - 2 7.4 25.9 2.4 7.2 17.9 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Utp14 PF04615.8 CDI85869.1 - 2.2 6.3 39.3 2.7 6.0 27.2 1.0 1 0 0 1 1 1 0 Utp14 protein TFIIA PF03153.8 CDI85869.1 - 2.5 7.9 47.8 3.3 7.4 33.1 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit AMP-binding PF00501.23 CDI85869.1 - 2.6 6.3 6.9 3.2 6.0 4.8 1.1 1 0 0 1 1 1 0 AMP-binding enzyme Serinc PF03348.10 CDI85869.1 - 2.9 6.5 25.3 5.4 5.6 17.5 1.4 1 1 0 1 1 1 0 Serine incorporator (Serinc) TT_ORF1 PF02956.9 CDI85869.1 - 3.1 6.1 20.4 4.5 5.6 14.1 1.3 1 0 0 1 1 1 0 TT viral orf 1 HemX PF04375.9 CDI85869.1 - 3.5 6.1 35.2 5 5.6 24.4 1.2 1 0 0 1 1 1 0 HemX DUF3584 PF12128.3 CDI85869.1 - 3.5 4.8 36.7 3.8 4.7 25.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) SpaB_C PF14028.1 CDI85869.1 - 3.5 7.1 9.9 4.2 6.8 6.9 1.1 1 0 0 1 1 1 0 SpaB C-terminal domain DUF2232 PF09991.4 CDI85869.1 - 4.1 6.3 8.0 6.5 5.6 5.5 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) PAT1 PF09770.4 CDI85869.1 - 4.8 5.2 54.0 5.9 5.0 37.5 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Ebola_NP PF05505.7 CDI85869.1 - 5 5.0 23.5 7.3 4.5 16.3 1.3 1 0 0 1 1 1 0 Ebola nucleoprotein Sin_N PF04801.8 CDI85869.1 - 5.4 5.7 29.8 6.5 5.5 20.7 1.0 1 0 0 1 1 1 0 Sin-like protein conserved region OmpH PF03938.9 CDI85869.1 - 5.9 6.7 47.1 7.8 6.4 32.6 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Cellulose_synt PF03552.9 CDI85869.1 - 7.8 4.6 12.7 9 4.4 8.8 1.1 1 0 0 1 1 1 0 Cellulose synthase DUF3357 PF11837.3 CDI85869.1 - 7.9 6.3 18.8 1.6e+02 2.1 5.9 2.9 1 1 1 2 2 2 0 Domain of unknown function (DUF3357) VID27 PF08553.5 CDI85869.1 - 8.2 4.5 20.7 9.8 4.2 14.4 1.2 1 0 0 1 1 1 0 VID27 cytoplasmic protein CRT10 PF08728.5 CDI85869.1 - 9 4.1 19.4 10 3.9 13.4 1.0 1 0 0 1 1 1 0 CRT10 Nha1_C PF08619.5 CDI85870.1 - 0.0039 16.5 17.0 0.0044 16.3 11.8 1.0 1 0 0 1 1 1 1 Alkali metal cation/H+ antiporter Nha1 C terminus Ycf1 PF05758.7 CDI85870.1 - 0.032 11.9 20.2 0.033 11.9 14.0 1.0 1 0 0 1 1 1 0 Ycf1 DUF2201_N PF13203.1 CDI85870.1 - 0.084 12.0 21.2 0.084 12.0 14.7 1.0 1 0 0 1 1 1 0 Putative metallopeptidase domain Herpes_UL87 PF03043.9 CDI85870.1 - 0.12 10.6 12.2 0.13 10.5 8.4 1.0 1 0 0 1 1 1 0 Herpesvirus UL87 family Zip PF02535.17 CDI85870.1 - 0.23 10.4 5.5 0.28 10.1 3.8 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Radical_SAM_N PF08497.5 CDI85870.1 - 0.28 10.0 12.8 0.35 9.7 8.8 1.0 1 0 0 1 1 1 0 Radical SAM N-terminal DUF4045 PF13254.1 CDI85870.1 - 0.29 10.3 20.3 0.34 10.1 14.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) DUF3260 PF11658.3 CDI85870.1 - 0.32 9.0 17.1 0.43 8.6 11.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3260) GAGA_bind PF06217.7 CDI85870.1 - 0.51 10.2 23.0 0.6 10.0 16.0 1.0 1 0 0 1 1 1 0 GAGA binding protein-like family Mem_trans PF03547.13 CDI85870.1 - 0.52 8.5 11.1 0.6 8.3 7.7 1.1 1 0 0 1 1 1 0 Membrane transport protein NHS PF15273.1 CDI85870.1 - 0.67 8.5 20.5 0.81 8.2 14.2 1.0 1 0 0 1 1 1 0 NHS-like Band_3_cyto PF07565.8 CDI85870.1 - 0.89 9.0 24.8 1.4 8.3 17.2 1.3 1 0 0 1 1 1 0 Band 3 cytoplasmic domain AUX_IAA PF02309.11 CDI85870.1 - 0.9 9.2 19.8 1.3 8.7 13.7 1.2 1 0 0 1 1 1 0 AUX/IAA family NARP1 PF12569.3 CDI85870.1 - 0.97 8.1 21.7 1.2 7.8 15.0 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Rtf2 PF04641.7 CDI85870.1 - 1.2 8.3 23.2 1.4 8.0 16.1 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger Pneumo_phosprot PF02478.11 CDI85870.1 - 1.3 8.5 7.3 1.6 8.1 5.1 1.1 1 0 0 1 1 1 0 Pneumovirus phosphoprotein Allexi_40kDa PF05549.6 CDI85870.1 - 1.6 7.9 16.4 1.8 7.7 11.3 1.1 1 0 0 1 1 1 0 Allexivirus 40kDa protein BPL_N PF09825.4 CDI85870.1 - 1.7 7.3 11.9 2 7.1 8.2 1.0 1 0 0 1 1 1 0 Biotin-protein ligase, N terminal DUF913 PF06025.7 CDI85870.1 - 1.7 7.3 15.6 2.4 6.8 10.8 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) PAT1 PF09770.4 CDI85870.1 - 1.7 6.7 65.5 1.9 6.6 45.4 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Otopetrin PF03189.8 CDI85870.1 - 1.8 7.4 11.1 2.2 7.1 7.7 1.2 1 0 0 1 1 1 0 Otopetrin HCO3_cotransp PF00955.16 CDI85870.1 - 1.9 7.0 7.4 2.1 6.9 5.1 1.2 1 0 0 1 1 1 0 HCO3- transporter family SID-1_RNA_chan PF13965.1 CDI85870.1 - 2.1 6.4 12.9 2.4 6.2 8.9 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 FNIP_N PF14636.1 CDI85870.1 - 2.2 8.7 24.0 4.1 7.8 16.6 1.5 1 0 0 1 1 1 0 Folliculin-interacting protein N-terminus CDC45 PF02724.9 CDI85870.1 - 2.2 6.2 21.6 2.6 5.9 15.0 1.0 1 0 0 1 1 1 0 CDC45-like protein DUF1510 PF07423.6 CDI85870.1 - 2.4 7.4 29.1 3.1 7.1 20.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DOR PF14839.1 CDI85870.1 - 2.8 7.6 29.8 3.4 7.3 20.7 1.3 1 0 0 1 1 1 0 DOR family Presenilin PF01080.12 CDI85870.1 - 2.9 6.5 14.9 3.5 6.3 10.3 1.2 1 0 0 1 1 1 0 Presenilin VID27 PF08553.5 CDI85870.1 - 3 5.9 19.6 3.2 5.8 13.6 1.0 1 0 0 1 1 1 0 VID27 cytoplasmic protein MMR1 PF08505.5 CDI85870.1 - 3.3 7.6 29.8 5 7.0 20.7 1.3 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein DUF844 PF05815.6 CDI85870.1 - 3.3 6.4 17.7 4.5 6.0 12.3 1.2 1 0 0 1 1 1 0 Baculovirus protein of unknown function (DUF844) CRT10 PF08728.5 CDI85870.1 - 4.4 5.1 15.2 4.9 5.0 10.5 1.1 1 0 0 1 1 1 0 CRT10 PLRV_ORF5 PF01690.12 CDI85870.1 - 5.1 6.1 25.7 6.1 5.8 17.8 1.0 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein DUF1675 PF07897.6 CDI85870.1 - 5.4 6.7 19.4 6.3 6.5 13.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) K_trans PF02705.11 CDI85870.1 - 5.4 5.2 6.8 6.4 5.0 4.7 1.1 1 0 0 1 1 1 0 K+ potassium transporter DUF342 PF03961.8 CDI85870.1 - 5.6 5.2 18.5 6.3 5.0 12.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DHHW PF14286.1 CDI85870.1 - 6 6.0 21.9 7.2 5.8 15.2 1.1 1 0 0 1 1 1 0 DHHW protein FAM60A PF15396.1 CDI85870.1 - 6 6.5 23.1 7 6.3 16.0 1.1 1 0 0 1 1 1 0 Protein Family FAM60A Pox_Rap94 PF03294.9 CDI85870.1 - 6.9 4.4 10.6 8.3 4.2 7.4 1.0 1 0 0 1 1 1 0 RNA polymerase-associated transcription specificity factor, Rap94 RNA_pol_Rpb1_5 PF04998.12 CDI85870.1 - 7 5.8 15.3 9.2 5.4 10.6 1.1 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 eIF-3_zeta PF05091.7 CDI85870.1 - 7 5.1 31.8 8.6 4.8 22.1 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) PIH1 PF08190.7 CDI85870.1 - 7.9 5.8 32.4 11 5.3 22.5 1.1 1 0 0 1 1 1 0 pre-RNA processing PIH1/Nop17 TCP PF03634.8 CDI85870.1 - 7.9 6.8 26.4 11 6.4 18.3 1.2 1 0 0 1 1 1 0 TCP family transcription factor Paf1 PF03985.8 CDI85870.1 - 8.1 5.0 31.1 9.9 4.7 21.6 1.0 1 0 0 1 1 1 0 Paf1 Hid1 PF12722.2 CDI85870.1 - 8.2 3.9 30.2 9.8 3.7 21.0 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein BTV_NS2 PF04514.7 CDI85870.1 - 8.3 5.1 20.1 9.8 4.9 13.9 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 DUF4366 PF14283.1 CDI85871.1 - 0.0045 16.4 8.6 0.0045 16.4 6.0 2.0 1 1 1 2 2 2 1 Domain of unknown function (DUF4366) PBP1_TM PF14812.1 CDI85871.1 - 0.026 14.7 3.8 0.026 14.7 2.6 2.7 2 1 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CcmD PF04995.9 CDI85871.1 - 1 9.1 0.0 1 9.1 0.0 5.0 3 2 0 3 3 3 0 Heme exporter protein D (CcmD) DUF1183 PF06682.7 CDI85871.1 - 8.6 5.8 25.1 11 5.4 17.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) K_channel_TID PF07941.6 CDI85873.1 - 0.0051 16.9 3.3 0.0051 16.9 2.3 2.5 3 1 0 3 3 1 1 Potassium channel Kv1.4 tandem inactivation domain AviRa PF11599.3 CDI85873.1 - 0.29 10.0 1.5 0.42 9.5 1.1 1.2 1 0 0 1 1 1 0 RRNA methyltransferase AviRa PPP4R2 PF09184.6 CDI85873.1 - 0.31 10.5 17.7 0.41 10.1 12.3 1.3 1 0 0 1 1 1 0 PPP4R2 RED_N PF07808.8 CDI85873.1 - 0.82 8.8 35.4 0.011 15.0 10.0 2.1 2 0 0 2 2 2 0 RED-like protein N-terminal region Herpes_UL87 PF03043.9 CDI85873.1 - 2.9 6.1 12.9 3.4 5.9 9.0 1.1 1 0 0 1 1 1 0 Herpesvirus UL87 family Exonuc_VII_L PF02601.10 CDI85873.1 - 3.3 6.8 24.6 3.6 6.7 17.1 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit RimM PF01782.13 CDI85873.1 - 3.9 7.4 5.1 8.2 6.4 3.6 1.7 1 1 0 1 1 1 0 RimM N-terminal domain Activator_LAG-3 PF11498.3 CDI85873.1 - 4.9 5.7 81.4 5.5 5.6 56.4 1.0 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Fmp27_WPPW PF10359.4 CDI85873.1 - 5.5 5.2 26.7 6.5 5.0 18.5 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Peptidase_M56 PF05569.6 CDI85873.1 - 7.9 5.3 8.2 10 4.9 5.7 1.1 1 0 0 1 1 1 0 BlaR1 peptidase M56 ICE2 PF08426.5 CDI85873.1 - 8.5 4.8 6.4 4.7 5.7 3.2 1.4 1 1 0 1 1 1 0 ICE2 DRY_EERY PF09750.4 CDI85873.1 - 9.6 6.3 20.5 4.2 7.4 2.5 2.2 2 0 0 2 2 2 0 Alternative splicing regulator RNA_pol_Rpb1_5 PF04998.12 CDI85873.1 - 9.6 5.3 12.8 14 4.8 8.9 1.2 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 START PF01852.14 CDI85877.1 - 8.8e-18 64.3 0.0 1.1e-17 64.0 0.0 1.0 1 0 0 1 1 1 1 START domain DUF3074 PF11274.3 CDI85877.1 - 0.00029 20.5 0.0 0.00089 18.9 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF3074) DUF1219 PF06755.7 CDI85877.1 - 0.014 14.9 0.0 0.021 14.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1219) Utp14 PF04615.8 CDI85878.1 - 0.61 8.1 45.9 0.72 7.9 31.8 1.0 1 0 0 1 1 1 0 Utp14 protein DUF1053 PF06327.9 CDI85880.1 - 0.044 14.1 4.9 0.86 9.9 0.1 2.4 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1053) DUF2361 PF10153.4 CDI85880.1 - 0.11 12.7 4.9 1.3 9.2 0.9 2.4 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2361) DivIC PF04977.10 CDI85880.1 - 0.41 10.1 20.3 0.64 9.5 1.9 2.4 2 0 0 2 2 2 0 Septum formation initiator LCD1 PF09798.4 CDI85880.1 - 1.5 6.7 7.8 1.9 6.3 0.4 2.2 2 0 0 2 2 2 0 DNA damage checkpoint protein AAA_23 PF13476.1 CDI85880.1 - 2.3 8.4 8.4 16 5.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain SAPS PF04499.10 CDI85881.1 - 1.7 7.1 29.6 1.9 7.0 20.5 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF2201_N PF13203.1 CDI85881.1 - 4.9 6.2 38.1 5.7 6.0 26.4 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain DUF1227 PF06777.6 CDI85883.1 - 1.5e-18 66.9 14.8 1.1e-16 60.8 2.9 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF1227) SGIII PF15467.1 CDI85883.1 - 0.00014 21.0 5.3 0.0002 20.6 3.7 1.2 1 0 0 1 1 1 1 Secretogranin-3 Pex14_N PF04695.8 CDI85883.1 - 0.00073 19.6 11.4 0.00082 19.4 7.9 1.3 1 0 0 1 1 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Tim54 PF11711.3 CDI85883.1 - 0.0084 14.7 5.8 0.0096 14.5 4.0 1.1 1 0 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 eIF3_subunit PF08597.5 CDI85883.1 - 0.015 14.9 9.8 0.016 14.7 6.8 1.1 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit Kei1 PF08552.6 CDI85883.1 - 0.016 14.8 4.0 0.021 14.5 2.8 1.2 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 AUX_IAA PF02309.11 CDI85883.1 - 0.026 14.2 7.4 0.026 14.2 5.2 1.2 1 0 0 1 1 1 0 AUX/IAA family Band_3_cyto PF07565.8 CDI85883.1 - 0.027 13.9 12.7 0.032 13.7 8.8 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain MRP-S31 PF15433.1 CDI85883.1 - 0.039 13.3 14.1 0.044 13.2 9.8 1.1 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 DUF702 PF05142.7 CDI85883.1 - 0.051 13.7 12.6 0.063 13.4 8.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF702) RP-C_C PF11800.3 CDI85883.1 - 0.052 13.2 11.5 0.057 13.1 8.0 1.1 1 0 0 1 1 1 0 Replication protein C C-terminal region SAPS PF04499.10 CDI85883.1 - 0.079 11.5 10.4 0.073 11.6 7.2 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein OmpH PF03938.9 CDI85883.1 - 0.082 12.8 33.8 0.087 12.7 23.4 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) SAGA-Tad1 PF12767.2 CDI85883.1 - 0.086 12.4 17.6 0.097 12.3 12.2 1.1 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit Het-C PF07217.6 CDI85883.1 - 0.098 10.8 8.7 0.086 11.0 6.0 1.0 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C Glyco_transf_15 PF01793.11 CDI85883.1 - 0.1 11.5 7.6 0.11 11.4 5.3 1.1 1 0 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase Ycf1 PF05758.7 CDI85883.1 - 0.12 10.0 11.0 0.11 10.2 7.7 1.0 1 0 0 1 1 1 0 Ycf1 DUF935 PF06074.7 CDI85883.1 - 0.15 10.7 12.9 0.17 10.5 8.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF935) PAT1 PF09770.4 CDI85883.1 - 0.19 9.9 34.2 0.2 9.8 23.7 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SPX PF03105.14 CDI85883.1 - 0.2 11.3 14.2 0.27 10.9 9.8 1.3 1 0 0 1 1 1 0 SPX domain DHHW PF14286.1 CDI85883.1 - 0.2 10.9 7.2 0.19 10.9 5.0 1.1 1 0 0 1 1 1 0 DHHW protein DUF4557 PF15101.1 CDI85883.1 - 0.21 11.4 23.6 0.26 11.1 16.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) Peptidase_S64 PF08192.6 CDI85883.1 - 0.21 9.8 7.7 0.2 9.9 5.4 1.0 1 0 0 1 1 1 0 Peptidase family S64 Med15 PF09606.5 CDI85883.1 - 0.21 9.7 46.4 0.23 9.6 32.1 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Peptidase_C58 PF03543.9 CDI85883.1 - 0.22 10.9 16.2 0.25 10.7 11.2 1.1 1 0 0 1 1 1 0 Yersinia/Haemophilus virulence surface antigen Herpes_env PF01673.13 CDI85883.1 - 0.26 9.7 6.2 0.28 9.6 4.3 1.1 1 0 0 1 1 1 0 Herpesvirus putative major envelope glycoprotein DUF2201_N PF13203.1 CDI85883.1 - 0.27 10.3 13.1 0.29 10.2 9.1 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain FAM176 PF14851.1 CDI85883.1 - 0.29 10.7 6.8 0.35 10.5 4.7 1.3 1 0 0 1 1 1 0 FAM176 family Spore_coat_CotO PF14153.1 CDI85883.1 - 0.31 10.4 20.0 0.37 10.2 13.9 1.1 1 0 0 1 1 1 0 Spore coat protein CotO FLO_LFY PF01698.11 CDI85883.1 - 0.32 9.7 12.0 0.33 9.7 8.3 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein FadA PF09403.5 CDI85883.1 - 0.45 10.5 15.0 0.62 10.0 10.4 1.3 1 0 0 1 1 1 0 Adhesion protein FadA Neur_chan_memb PF02932.11 CDI85883.1 - 0.46 10.3 7.6 0.49 10.2 5.3 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Mem_trans PF03547.13 CDI85883.1 - 0.46 8.7 3.0 0.46 8.7 2.1 1.1 1 0 0 1 1 1 0 Membrane transport protein DUF4220 PF13968.1 CDI85883.1 - 0.6 9.1 4.3 0.6 9.1 2.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4220) Dala_Dala_lig_N PF01820.16 CDI85883.1 - 0.6 10.4 5.4 0.86 9.9 3.7 1.4 1 0 0 1 1 1 0 D-ala D-ala ligase N-terminus DUF1675 PF07897.6 CDI85883.1 - 0.62 9.8 10.0 0.73 9.6 6.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) eIF-3_zeta PF05091.7 CDI85883.1 - 0.63 8.5 17.8 0.68 8.4 12.3 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Ndc1_Nup PF09531.5 CDI85883.1 - 0.64 8.3 9.5 0.61 8.4 6.6 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup FimP PF09766.4 CDI85883.1 - 0.67 8.9 25.2 0.96 8.4 17.4 1.3 1 0 0 1 1 1 0 Fms-interacting protein SMN PF06003.7 CDI85883.1 - 0.73 8.8 3.5 0.79 8.7 2.4 1.1 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) Peptidase_U57 PF05582.7 CDI85883.1 - 0.78 8.6 10.7 1 8.2 7.4 1.2 1 0 0 1 1 1 0 YabG peptidase U57 Pex16 PF08610.5 CDI85883.1 - 0.8 8.6 15.1 0.99 8.3 10.5 1.1 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) DUF775 PF05603.7 CDI85883.1 - 0.8 9.1 15.1 1.2 8.6 10.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF775) DUF853 PF05872.7 CDI85883.1 - 0.82 7.9 13.6 0.95 7.7 9.4 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) Zip PF02535.17 CDI85883.1 - 0.84 8.5 2.4 0.87 8.5 1.7 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Birna_RdRp PF04197.7 CDI85883.1 - 0.93 7.4 8.2 1 7.2 5.7 1.0 1 0 0 1 1 1 0 Birnavirus RNA dependent RNA polymerase (VP1) PIH1 PF08190.7 CDI85883.1 - 0.94 8.8 18.4 1.1 8.6 12.8 1.1 1 0 0 1 1 1 0 pre-RNA processing PIH1/Nop17 MTP18 PF10558.4 CDI85883.1 - 0.98 9.2 3.0 1.4 8.7 2.0 1.4 1 1 0 1 1 1 0 Mitochondrial 18 KDa protein (MTP18) Cellulose_synt PF03552.9 CDI85883.1 - 0.98 7.6 3.9 0.92 7.7 2.7 1.0 1 0 0 1 1 1 0 Cellulose synthase NARP1 PF12569.3 CDI85883.1 - 1.2 7.8 15.2 1.3 7.6 10.5 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DUF4638 PF15472.1 CDI85883.1 - 1.2 8.6 11.3 1.4 8.4 7.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) Raftlin PF15250.1 CDI85883.1 - 1.3 7.4 13.8 1.6 7.2 9.6 1.1 1 0 0 1 1 1 0 Raftlin Paramyxo_ncap PF00973.14 CDI85883.1 - 1.4 7.5 9.7 1.4 7.5 6.8 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein DUF3492 PF11997.3 CDI85883.1 - 1.4 8.3 6.8 1.7 8.1 4.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3492) CDC45 PF02724.9 CDI85883.1 - 1.6 6.6 14.6 1.7 6.5 10.1 1.1 1 0 0 1 1 1 0 CDC45-like protein Tom37_C PF11801.3 CDI85883.1 - 1.6 8.5 16.7 2.2 8.1 11.5 1.1 1 0 0 1 1 1 0 Tom37 C-terminal domain Hom_end_hint PF05203.11 CDI85883.1 - 1.7 8.3 9.7 2.1 8.0 6.8 1.1 1 0 0 1 1 1 0 Hom_end-associated Hint YjgP_YjgQ PF03739.9 CDI85883.1 - 1.7 7.3 6.9 1.7 7.3 4.8 1.1 1 0 0 1 1 1 0 Predicted permease YjgP/YjgQ family Peroxin-13_N PF04088.8 CDI85883.1 - 1.7 8.5 7.4 3.3 7.6 5.1 1.6 1 0 0 1 1 1 0 Peroxin 13, N-terminal region Hid1 PF12722.2 CDI85883.1 - 2 6.0 17.5 2.1 5.9 12.1 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Nucleoside_tran PF01733.13 CDI85883.1 - 2.2 7.3 5.0 2.7 7.0 3.4 1.1 1 0 0 1 1 1 0 Nucleoside transporter Rtf2 PF04641.7 CDI85883.1 - 2.4 7.2 17.2 3.1 6.9 11.9 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger DUF2828 PF11443.3 CDI85883.1 - 2.4 6.2 10.5 2.8 6.0 7.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) TFIIA PF03153.8 CDI85883.1 - 2.4 7.9 26.7 2.6 7.8 18.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF3464 PF11947.3 CDI85883.1 - 2.6 7.4 12.2 3.7 6.9 8.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) Paf1 PF03985.8 CDI85883.1 - 2.7 6.6 22.8 3.2 6.3 15.8 1.1 1 0 0 1 1 1 0 Paf1 Exonuc_VII_L PF02601.10 CDI85883.1 - 3.3 6.8 16.5 3.3 6.8 11.4 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit FUSC PF04632.7 CDI85883.1 - 3.4 5.9 9.5 3.5 5.9 6.6 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family V_ATPase_I PF01496.14 CDI85883.1 - 3.5 5.3 9.9 3.4 5.3 6.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF1980 PF09323.5 CDI85883.1 - 3.9 7.1 14.9 5.4 6.7 10.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) DUF4175 PF13779.1 CDI85883.1 - 4.3 4.9 44.4 5 4.7 30.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) HGTP_anticodon2 PF12745.2 CDI85883.1 - 4.3 6.3 15.1 5.7 5.9 10.4 1.2 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs LIM_bind PF01803.11 CDI85883.1 - 4.3 6.3 17.1 5.3 6.0 11.9 1.2 1 0 0 1 1 1 0 LIM-domain binding protein DALR_2 PF09190.6 CDI85883.1 - 4.5 7.5 8.6 76 3.6 6.0 2.7 1 1 0 1 1 1 0 DALR domain FAM60A PF15396.1 CDI85883.1 - 4.6 6.9 13.4 5.7 6.6 9.3 1.1 1 0 0 1 1 1 0 Protein Family FAM60A LMBR1 PF04791.11 CDI85883.1 - 4.7 5.6 6.7 4.8 5.6 4.6 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein AIF_C PF14721.1 CDI85883.1 - 4.8 7.4 11.4 6.7 6.9 7.9 1.4 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term CPSF100_C PF13299.1 CDI85883.1 - 5.4 7.1 13.5 7.1 6.7 9.3 1.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal RR_TM4-6 PF06459.7 CDI85883.1 - 5.5 6.8 16.4 7.4 6.3 11.4 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Med13_N PF11597.3 CDI85883.1 - 5.8 5.4 12.9 6.7 5.2 8.9 1.1 1 0 0 1 1 1 0 Mediator complex subunit 13 N-terminal NMDAR2_C PF10565.4 CDI85883.1 - 6.6 5.2 20.5 7.7 5.0 14.2 1.1 1 0 0 1 1 1 0 N-methyl D-aspartate receptor 2B3 C-terminus DUF1764 PF08576.5 CDI85883.1 - 6.9 7.5 21.7 10 6.9 15.0 1.3 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) DUF605 PF04652.11 CDI85883.1 - 7.2 5.8 21.3 8.4 5.6 14.8 1.1 1 0 0 1 1 1 0 Vta1 like Folate_carrier PF01770.13 CDI85883.1 - 7.3 4.9 9.9 9.6 4.5 6.8 1.1 1 0 0 1 1 1 0 Reduced folate carrier UPF0560 PF10577.4 CDI85883.1 - 7.4 4.6 22.9 8.7 4.4 15.9 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Pal1 PF08316.6 CDI85883.1 - 7.5 6.9 7.1 9.7 6.6 4.9 1.3 1 0 0 1 1 1 0 Pal1 cell morphology protein MSA-2c PF12238.3 CDI85883.1 - 7.6 6.1 14.6 2.5 7.7 8.3 1.6 2 0 0 2 2 1 0 Merozoite surface antigen 2c DUF2347 PF09804.4 CDI85883.1 - 7.7 5.6 9.4 8.7 5.5 6.5 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2347) Peptidase_S15 PF02129.13 CDI85883.1 - 7.8 5.8 11.5 8.9 5.6 8.0 1.1 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Baculo_PP31 PF05311.6 CDI85883.1 - 8.1 5.6 15.6 12 5.0 10.8 1.3 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) DDHD PF02862.12 CDI85883.1 - 8.9 6.0 18.8 11 5.7 13.0 1.1 1 0 0 1 1 1 0 DDHD domain SR-25 PF10500.4 CDI85885.1 - 0.00087 18.8 4.2 0.0012 18.3 2.9 1.3 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Senescence_reg PF04520.8 CDI85885.1 - 0.11 13.0 4.1 0.21 12.0 2.8 1.4 1 0 0 1 1 1 0 Senescence regulator DUF966 PF06136.8 CDI85885.1 - 2 7.7 7.3 2.7 7.3 5.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Macoilin PF09726.4 CDI85885.1 - 6.3 4.9 7.3 8.5 4.5 5.0 1.1 1 0 0 1 1 1 0 Transmembrane protein DUF979 PF06166.7 CDI85886.1 - 0.041 12.8 1.1 0.043 12.7 0.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF979) CDK2AP PF09806.4 CDI85886.1 - 0.12 12.5 10.1 0.15 12.2 7.0 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein DUF243 PF03103.12 CDI85886.1 - 1.6 8.8 8.5 3.7 7.7 5.9 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF243) TFIIA PF03153.8 CDI85886.1 - 4.9 6.9 9.9 5.8 6.7 6.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PsbW PF07123.7 CDI85886.1 - 6.1 6.9 9.3 1.2 9.1 3.0 1.8 1 1 1 2 2 2 0 Photosystem II reaction centre W protein (PsbW) DUF2457 PF10446.4 CDI85887.1 - 0.028 13.1 34.9 0.03 13.0 24.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DUF1754 PF08555.5 CDI85887.1 - 0.1 13.2 35.0 0.12 12.9 24.3 1.1 1 0 0 1 1 1 0 Eukaryotic family of unknown function (DUF1754) BUD22 PF09073.5 CDI85887.1 - 0.24 10.4 36.6 0.24 10.4 25.3 1.0 1 0 0 1 1 1 0 BUD22 Pox_Ag35 PF03286.9 CDI85887.1 - 0.93 8.9 29.6 1.1 8.7 20.5 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Prothymosin PF03247.9 CDI85887.1 - 1.3 9.1 49.6 1.5 8.9 34.4 1.2 1 0 0 1 1 1 0 Prothymosin/parathymosin family DUF1168 PF06658.7 CDI85887.1 - 1.7 8.1 33.6 2 7.9 23.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) Rtf2 PF04641.7 CDI85887.1 - 5.8 6.0 27.5 5.8 6.0 19.0 1.0 1 0 0 1 1 1 0 Rtf2 RING-finger DUF2052 PF09747.4 CDI85887.1 - 7.3 6.4 31.6 7.6 6.4 21.9 1.0 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) GETHR PF05671.6 CDI85889.1 - 0.00057 18.9 7.5 0.00057 18.9 5.2 7.7 3 2 2 5 5 5 2 GETHR pentapeptide repeat (5 copies) IncA PF04156.9 CDI85890.1 - 0.0096 15.5 5.9 0.013 15.0 4.1 1.2 1 0 0 1 1 1 1 IncA protein MCR_alpha PF02249.12 CDI85890.1 - 0.46 10.5 2.8 0.67 9.9 1.9 1.2 1 0 0 1 1 1 0 Methyl-coenzyme M reductase alpha subunit, C-terminal domain Ribosomal_60s PF00428.14 CDI85890.1 - 1.6 9.1 13.7 2.4 8.6 9.5 1.3 1 0 0 1 1 1 0 60s Acidic ribosomal protein RskA PF10099.4 CDI85890.1 - 4.1 7.0 11.0 7.8 6.1 7.6 1.5 1 1 0 1 1 1 0 Anti-sigma-K factor rskA SR-25 PF10500.4 CDI85891.1 - 0.0015 18.0 1.6 0.0015 18.0 1.1 3.2 3 0 0 3 3 3 1 Nuclear RNA-splicing-associated protein Suf PF05843.9 CDI85891.1 - 0.0042 16.8 2.7 0.0068 16.1 1.9 1.4 1 0 0 1 1 1 1 Suppressor of forked protein (Suf) Spt20 PF12090.3 CDI85891.1 - 0.014 14.7 5.3 0.028 13.7 3.7 1.4 1 0 0 1 1 1 0 Spt20 family Peptidase_C58 PF03543.9 CDI85891.1 - 0.05 13.0 10.4 0.092 12.2 7.2 1.4 1 0 0 1 1 1 0 Yersinia/Haemophilus virulence surface antigen FimP PF09766.4 CDI85891.1 - 0.44 9.5 16.3 0.67 8.9 11.3 1.2 1 0 0 1 1 1 0 Fms-interacting protein PH_4 PF15404.1 CDI85891.1 - 0.66 9.4 6.6 1.4 8.4 4.6 1.4 1 0 0 1 1 1 0 Pleckstrin homology domain EIIBC-GUT_N PF03612.9 CDI85891.1 - 3.7 7.1 6.3 9.2 5.8 4.4 1.6 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Serinc PF03348.10 CDI85891.1 - 3.8 6.1 5.4 6.4 5.3 3.7 1.3 1 0 0 1 1 1 0 Serine incorporator (Serinc) DUF4557 PF15101.1 CDI85891.1 - 9.5 6.0 16.1 21 4.8 11.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) SseC PF04888.7 CDI85892.1 - 5.1e-06 26.0 8.6 7.3e-06 25.5 5.9 1.2 1 0 0 1 1 1 1 Secretion system effector C (SseC) like family Med15 PF09606.5 CDI85892.1 - 0.3 9.2 40.6 0.39 8.8 28.2 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Vfa1 PF08432.5 CDI85892.1 - 0.33 10.9 20.3 0.77 9.7 5.2 2.4 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 Alg14 PF08660.6 CDI85892.1 - 1.1 9.2 3.1 2.6 8.0 2.2 1.6 1 0 0 1 1 1 0 Oligosaccharide biosynthesis protein Alg14 like MIP-T3 PF10243.4 CDI85892.1 - 7.8 4.8 51.7 21 3.3 35.8 1.6 1 1 0 1 1 1 0 Microtubule-binding protein MIP-T3 CPSF100_C PF13299.1 CDI85892.1 - 7.9 6.6 15.7 1.7 8.7 2.5 2.4 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal Daxx PF03344.10 CDI85893.1 - 0.065 11.7 25.7 0.071 11.5 17.8 1.0 1 0 0 1 1 1 0 Daxx Family DUF1510 PF07423.6 CDI85893.1 - 0.07 12.4 27.7 0.08 12.3 19.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Vfa1 PF08432.5 CDI85893.1 - 0.082 12.9 23.3 0.089 12.8 16.2 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DDHD PF02862.12 CDI85893.1 - 0.1 12.3 21.1 0.11 12.2 14.6 1.1 1 0 0 1 1 1 0 DDHD domain Zip PF02535.17 CDI85893.1 - 0.1 11.5 9.0 0.1 11.6 6.3 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter DUF2052 PF09747.4 CDI85893.1 - 0.14 12.0 30.3 0.16 11.9 21.0 1.1 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) CDC45 PF02724.9 CDI85893.1 - 0.14 10.1 23.6 0.15 10.0 16.4 1.0 1 0 0 1 1 1 0 CDC45-like protein Tim54 PF11711.3 CDI85893.1 - 0.17 10.4 18.4 0.19 10.2 12.8 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 U79_P34 PF03064.11 CDI85893.1 - 0.22 11.0 19.7 0.24 10.8 13.7 1.0 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Pox_Ag35 PF03286.9 CDI85893.1 - 0.22 11.0 17.7 0.25 10.8 12.3 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DDRGK PF09756.4 CDI85893.1 - 0.3 10.4 36.0 0.33 10.3 24.9 1.1 1 0 0 1 1 1 0 DDRGK domain SprA-related PF12118.3 CDI85893.1 - 0.33 10.2 51.1 0.41 9.9 35.4 1.1 1 0 0 1 1 1 0 SprA-related family Raftlin PF15250.1 CDI85893.1 - 0.34 9.3 19.9 0.37 9.2 13.8 1.0 1 0 0 1 1 1 0 Raftlin DUF4045 PF13254.1 CDI85893.1 - 0.4 9.9 19.9 0.45 9.7 13.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) FAM60A PF15396.1 CDI85893.1 - 0.42 10.3 17.3 0.47 10.1 12.0 1.0 1 0 0 1 1 1 0 Protein Family FAM60A Rtf2 PF04641.7 CDI85893.1 - 0.42 9.7 22.0 0.49 9.5 15.2 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger SAPS PF04499.10 CDI85893.1 - 0.44 9.1 22.9 0.47 9.0 15.9 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein NCKAP5 PF15246.1 CDI85893.1 - 0.48 9.7 23.6 0.48 9.7 16.3 1.0 1 0 0 1 1 1 0 Nck-associated protein 5, Peripheral clock protein Spore_coat_CotO PF14153.1 CDI85893.1 - 0.48 9.8 32.6 0.74 9.2 22.6 1.3 1 0 0 1 1 1 0 Spore coat protein CotO YqfQ PF14181.1 CDI85893.1 - 0.55 10.2 25.5 0.76 9.7 17.7 1.3 1 0 0 1 1 1 0 YqfQ-like protein NARP1 PF12569.3 CDI85893.1 - 0.62 8.7 23.9 0.7 8.5 16.6 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 TRAP_alpha PF03896.11 CDI85893.1 - 0.63 8.9 12.1 0.71 8.8 8.4 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit CKAP2_C PF15297.1 CDI85893.1 - 0.71 8.6 23.6 0.86 8.3 16.3 1.1 1 0 0 1 1 1 0 Cytoskeleton-associated protein 2 C-terminus Trypan_PARP PF05887.6 CDI85893.1 - 0.72 9.6 6.1 0.85 9.4 4.2 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Presenilin PF01080.12 CDI85893.1 - 0.74 8.5 17.4 0.88 8.3 12.0 1.0 1 0 0 1 1 1 0 Presenilin RR_TM4-6 PF06459.7 CDI85893.1 - 0.88 9.4 26.3 1.1 9.0 18.2 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF2126 PF09899.4 CDI85893.1 - 0.99 7.3 14.3 1.1 7.2 9.9 1.0 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) DUF3886 PF13025.1 CDI85893.1 - 1.1 9.3 40.7 0.39 10.7 5.5 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3886) Caldesmon PF02029.10 CDI85893.1 - 1.4 7.2 26.6 1.5 7.1 18.4 1.0 1 0 0 1 1 1 0 Caldesmon Pal1 PF08316.6 CDI85893.1 - 1.4 9.3 10.6 1.9 8.9 7.3 1.3 1 0 0 1 1 1 0 Pal1 cell morphology protein Hid1 PF12722.2 CDI85893.1 - 1.5 6.4 23.5 1.6 6.2 16.3 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF966 PF06136.8 CDI85893.1 - 1.7 7.9 16.8 1.9 7.8 11.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) VID27 PF08553.5 CDI85893.1 - 2 6.5 17.9 2.1 6.4 12.4 1.0 1 0 0 1 1 1 0 VID27 cytoplasmic protein GAGA_bind PF06217.7 CDI85893.1 - 2 8.2 20.9 2.2 8.1 14.5 1.0 1 0 0 1 1 1 0 GAGA binding protein-like family DUF3449 PF11931.3 CDI85893.1 - 2.1 7.8 22.1 2.6 7.4 15.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3449) Sec62 PF03839.11 CDI85893.1 - 2.2 7.6 21.1 2.2 7.6 14.6 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 RP-C_C PF11800.3 CDI85893.1 - 2.3 7.8 22.5 2.7 7.6 15.6 1.1 1 0 0 1 1 1 0 Replication protein C C-terminal region DUF4220 PF13968.1 CDI85893.1 - 2.4 7.1 11.8 2.6 7.0 8.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4220) NPR3 PF03666.8 CDI85893.1 - 2.5 6.5 21.0 2.9 6.3 14.5 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Baculo_PP31 PF05311.6 CDI85893.1 - 2.7 7.1 18.8 3.1 6.9 13.0 1.1 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) CENP-T PF15511.1 CDI85893.1 - 2.9 7.0 24.0 3.1 6.9 16.6 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T SMN PF06003.7 CDI85893.1 - 3.1 6.8 9.5 3.5 6.6 6.6 1.1 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) Asp-B-Hydro_N PF05279.6 CDI85893.1 - 3.3 7.5 25.0 3.8 7.3 17.3 1.0 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region DUF913 PF06025.7 CDI85893.1 - 3.7 6.2 14.1 4.4 5.9 9.8 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) SID-1_RNA_chan PF13965.1 CDI85893.1 - 3.7 5.6 14.9 3.7 5.6 10.3 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 CPSF100_C PF13299.1 CDI85893.1 - 3.7 7.7 19.7 4.5 7.4 13.7 1.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal PLRV_ORF5 PF01690.12 CDI85893.1 - 4.7 6.2 22.9 5.3 6.0 15.9 1.0 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein RNA_pol_Rpb1_5 PF04998.12 CDI85893.1 - 5.1 6.2 13.5 5.5 6.1 9.3 1.0 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 Peptidase_S64 PF08192.6 CDI85893.1 - 5.2 5.2 15.6 5.4 5.2 10.8 1.0 1 0 0 1 1 1 0 Peptidase family S64 Paf1 PF03985.8 CDI85893.1 - 5.3 5.6 33.2 5.9 5.5 23.0 1.1 1 0 0 1 1 1 0 Paf1 DHHW PF14286.1 CDI85893.1 - 5.5 6.1 19.4 6.2 6.0 13.5 1.0 1 0 0 1 1 1 0 DHHW protein Neur_chan_memb PF02932.11 CDI85893.1 - 5.8 6.7 17.1 6.2 6.6 11.8 1.0 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF2146 PF10220.4 CDI85893.1 - 6.5 4.6 19.9 6.8 4.5 13.8 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2146) Ycf1 PF05758.7 CDI85893.1 - 7.1 4.2 27.0 7.5 4.1 18.7 1.0 1 0 0 1 1 1 0 Ycf1 Peptidase_U57 PF05582.7 CDI85893.1 - 7.2 5.4 15.9 10 4.9 11.0 1.3 1 0 0 1 1 1 0 YabG peptidase U57 CMV_1a PF12467.3 CDI85893.1 - 7.4 6.9 16.1 8.5 6.7 11.2 1.2 1 0 0 1 1 1 0 Cucumber mosaic virus 1a protein family AAA_11 PF13086.1 CDI85893.1 - 7.5 6.0 21.9 8.3 5.9 15.2 1.1 1 0 0 1 1 1 0 AAA domain AUX_IAA PF02309.11 CDI85893.1 - 8 6.1 20.0 9.7 5.8 13.9 1.1 1 0 0 1 1 1 0 AUX/IAA family DUF1675 PF07897.6 CDI85893.1 - 8.3 6.1 18.6 9.7 5.9 12.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) Hom_end_hint PF05203.11 CDI85893.1 - 8.4 6.0 15.7 11 5.7 10.9 1.3 1 0 0 1 1 1 0 Hom_end-associated Hint Parvo_coat PF00740.13 CDI85893.1 - 9 5.1 21.7 9.9 4.9 15.0 1.0 1 0 0 1 1 1 0 Parvovirus coat protein VP2 MACPF PF01823.14 CDI85893.1 - 9 5.9 12.6 12 5.4 8.7 1.1 1 0 0 1 1 1 0 MAC/Perforin domain AvrE PF11725.3 CDI85893.1 - 9.2 3.1 26.1 9.5 3.0 18.1 1.0 1 0 0 1 1 1 0 Pathogenicity factor Paramyxo_ncap PF00973.14 CDI85893.1 - 9.2 4.8 21.2 9.7 4.7 14.7 1.0 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Cellulose_synt PF03552.9 CDI85893.1 - 9.2 4.4 10.8 9.8 4.3 7.5 1.0 1 0 0 1 1 1 0 Cellulose synthase BORG_CEP PF14957.1 CDI85893.1 - 9.8 7.1 17.2 13 6.7 11.9 1.3 1 0 0 1 1 1 0 Cdc42 effector eIF-3_zeta PF05091.7 CDI85893.1 - 9.9 4.6 26.6 11 4.4 18.5 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) FLO_LFY PF01698.11 CDI85893.1 - 10 4.8 23.5 12 4.6 16.3 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein RNA_pol_Rpb1_1 PF04997.7 CDI85894.1 - 9.8e-41 140.1 0.0 9.8e-41 140.1 0.0 2.0 1 1 1 2 2 1 1 RNA polymerase Rpb1, domain 1 SprA-related PF12118.3 CDI85894.1 - 0.00075 18.9 25.2 0.00086 18.7 17.4 1.1 1 0 0 1 1 1 1 SprA-related family AIF_C PF14721.1 CDI85894.1 - 0.0018 18.5 6.8 0.0028 17.9 4.7 1.2 1 0 0 1 1 1 1 Apoptosis-inducing factor, mitochondrion-associated, C-term Pox_Ag35 PF03286.9 CDI85894.1 - 0.0028 17.1 4.4 0.0037 16.8 3.0 1.3 1 0 0 1 1 1 1 Pox virus Ag35 surface protein zf-DHHC PF01529.15 CDI85894.1 - 0.0094 15.3 0.7 0.011 15.1 0.5 1.2 1 0 0 1 1 1 1 DHHC palmitoyltransferase eIF-3_zeta PF05091.7 CDI85894.1 - 0.02 13.5 14.1 0.022 13.3 9.7 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Suf PF05843.9 CDI85894.1 - 0.059 13.1 17.4 0.08 12.6 12.0 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) UPF0560 PF10577.4 CDI85894.1 - 0.064 11.5 15.5 0.067 11.4 10.7 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 TFIIA PF03153.8 CDI85894.1 - 0.077 12.8 22.8 0.086 12.7 15.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PAT1 PF09770.4 CDI85894.1 - 0.092 10.9 35.5 0.1 10.8 24.6 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 AAA_23 PF13476.1 CDI85894.1 - 0.12 12.6 14.6 0.15 12.3 10.1 1.2 1 0 0 1 1 1 0 AAA domain FLO_LFY PF01698.11 CDI85894.1 - 0.13 11.0 8.5 0.15 10.8 5.9 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein DUF4407 PF14362.1 CDI85894.1 - 0.14 11.0 12.7 0.16 10.9 8.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Baculo_PP31 PF05311.6 CDI85894.1 - 0.17 11.1 11.0 0.21 10.8 7.6 1.1 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) FimP PF09766.4 CDI85894.1 - 0.17 10.8 23.7 0.23 10.4 16.4 1.2 1 0 0 1 1 1 0 Fms-interacting protein PPP4R2 PF09184.6 CDI85894.1 - 0.18 11.3 9.6 0.24 10.9 6.6 1.1 1 0 0 1 1 1 0 PPP4R2 RR_TM4-6 PF06459.7 CDI85894.1 - 0.19 11.5 10.2 0.25 11.1 7.1 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DDHD PF02862.12 CDI85894.1 - 0.24 11.1 9.7 0.3 10.8 6.7 1.1 1 0 0 1 1 1 0 DDHD domain Med15 PF09606.5 CDI85894.1 - 0.25 9.5 46.6 0.3 9.2 32.3 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF605 PF04652.11 CDI85894.1 - 0.26 10.6 18.1 0.32 10.3 12.6 1.2 1 0 0 1 1 1 0 Vta1 like Peptidase_U57 PF05582.7 CDI85894.1 - 0.44 9.4 7.0 0.52 9.2 4.9 1.2 1 0 0 1 1 1 0 YabG peptidase U57 Band_3_cyto PF07565.8 CDI85894.1 - 0.63 9.4 13.0 0.76 9.2 9.0 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain CPSF100_C PF13299.1 CDI85894.1 - 0.65 10.1 9.0 0.9 9.7 6.2 1.3 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal PIH1 PF08190.7 CDI85894.1 - 0.79 9.1 19.6 1.1 8.6 13.6 1.1 1 0 0 1 1 1 0 pre-RNA processing PIH1/Nop17 DUF3276 PF11680.3 CDI85894.1 - 1 9.1 7.6 1.6 8.5 5.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3276) GAGA_bind PF06217.7 CDI85894.1 - 1.1 9.1 15.4 1.4 8.7 10.7 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family MDFI PF15316.1 CDI85894.1 - 1.2 9.1 7.6 1.5 8.8 5.3 1.2 1 0 0 1 1 1 0 MyoD family inhibitor Kei1 PF08552.6 CDI85894.1 - 1.3 8.6 6.2 1.7 8.2 4.3 1.2 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 Dala_Dala_lig_N PF01820.16 CDI85894.1 - 1.6 9.0 6.3 2.7 8.3 4.4 1.4 1 0 0 1 1 1 0 D-ala D-ala ligase N-terminus Anoctamin PF04547.7 CDI85894.1 - 1.8 7.0 6.9 2.1 6.9 4.8 1.1 1 0 0 1 1 1 0 Calcium-activated chloride channel Serinc PF03348.10 CDI85894.1 - 2.5 6.6 12.0 3.1 6.4 8.3 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) SID-1_RNA_chan PF13965.1 CDI85894.1 - 2.8 6.0 5.7 3.2 5.8 4.0 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 NARP1 PF12569.3 CDI85894.1 - 3.6 6.2 15.7 5.2 5.7 10.9 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DHHW PF14286.1 CDI85894.1 - 4.3 6.5 9.7 5.5 6.2 6.7 1.1 1 0 0 1 1 1 0 DHHW protein Neur_chan_memb PF02932.11 CDI85894.1 - 4.5 7.0 7.4 5.4 6.8 5.1 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Pex16 PF08610.5 CDI85894.1 - 5.2 5.9 12.6 7.7 5.3 8.7 1.3 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) EIIBC-GUT_N PF03612.9 CDI85894.1 - 5.3 6.6 10.4 7.6 6.1 7.2 1.2 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Presenilin PF01080.12 CDI85894.1 - 8.3 5.1 6.6 10 4.8 4.6 1.1 1 0 0 1 1 1 0 Presenilin Nop53 PF07767.6 CDI85895.1 - 0.028 13.4 53.2 0.037 13.0 36.9 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) DUF2201_N PF13203.1 CDI85895.1 - 0.043 13.0 28.8 0.051 12.7 19.9 1.0 1 0 0 1 1 1 0 Putative metallopeptidase domain CDC45 PF02724.9 CDI85895.1 - 0.044 11.8 27.3 0.051 11.6 18.9 1.0 1 0 0 1 1 1 0 CDC45-like protein TFIIF_alpha PF05793.7 CDI85895.1 - 0.11 10.7 41.4 0.15 10.3 28.7 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF1510 PF07423.6 CDI85895.1 - 0.22 10.8 42.2 0.28 10.5 29.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) MIP-T3 PF10243.4 CDI85895.1 - 0.34 9.3 62.7 0.36 9.2 43.4 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 SOBP PF15279.1 CDI85895.1 - 0.38 11.0 26.1 0.44 10.8 18.1 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein SAGA-Tad1 PF12767.2 CDI85895.1 - 0.78 9.3 28.3 0.9 9.1 19.6 1.1 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit DUF2413 PF10310.4 CDI85895.1 - 0.85 8.3 44.8 0.97 8.1 31.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) Draxin PF15550.1 CDI85895.1 - 0.85 9.2 27.3 1.1 8.8 18.9 1.2 1 0 0 1 1 1 0 Draxin PLRV_ORF5 PF01690.12 CDI85895.1 - 0.97 8.5 30.2 1 8.3 20.9 1.0 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein RNA_pol_Rpb1_1 PF04997.7 CDI85895.1 - 1.2 8.3 28.4 1.4 8.0 19.7 1.1 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 1 Suf PF05843.9 CDI85895.1 - 1.2 8.7 30.0 1.5 8.5 20.8 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) PBP_sp32 PF07222.7 CDI85895.1 - 1.6 7.8 36.1 2 7.5 25.0 1.1 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Paf1 PF03985.8 CDI85895.1 - 2.1 7.0 33.9 2.8 6.5 23.5 1.2 1 0 0 1 1 1 0 Paf1 DUF1675 PF07897.6 CDI85895.1 - 2.9 7.6 29.2 3.3 7.4 20.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) Neur_chan_memb PF02932.11 CDI85895.1 - 3.4 7.4 24.3 4.2 7.1 16.9 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region HGTP_anticodon2 PF12745.2 CDI85895.1 - 4.3 6.4 30.7 5.8 5.9 21.3 1.2 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs CAF-1_p150 PF11600.3 CDI85895.1 - 4.8 6.5 71.2 6 6.1 49.3 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF4647 PF15504.1 CDI85895.1 - 6.1 5.5 39.1 7.5 5.2 27.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4647) Trypan_PARP PF05887.6 CDI85895.1 - 6.5 6.5 11.5 8.3 6.2 8.0 1.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DUF572 PF04502.8 CDI85895.1 - 7.2 5.7 43.0 8.6 5.4 29.8 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF572) Hid1 PF12722.2 CDI85895.1 - 9.3 3.7 29.6 11 3.5 20.5 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein MIP-T3 PF10243.4 CDI85896.1 - 0.025 13.0 33.3 0.029 12.8 23.1 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DUF1777 PF08648.7 CDI85896.1 - 3.9 7.1 107.6 1.5e+04 -23.6 74.5 3.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1777) Cwf_Cwc_15 PF04889.7 CDI85897.1 - 2.4 7.7 34.5 5.2 6.7 1.4 2.3 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Peptidase_S49_N PF08496.5 CDI85897.1 - 4.6 7.0 23.0 4.7 6.9 1.0 2.4 2 0 0 2 2 2 0 Peptidase family S49 N-terminal DUF4355 PF14265.1 CDI85897.1 - 9.3 6.2 40.5 0.21 11.5 6.6 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4355) Med15 PF09606.5 CDI85900.1 - 1 7.5 50.6 1.8 6.6 35.1 1.4 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Exonuc_VII_L PF02601.10 CDI85900.1 - 2.2 7.3 17.1 3.9 6.5 11.9 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit Neur_chan_memb PF02932.11 CDI85900.1 - 8.3 6.2 7.3 20 4.9 5.0 1.8 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF4010 PF13194.1 CDI85904.1 - 0.026 13.8 5.6 0.035 13.3 3.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4010) AMP-binding PF00501.23 CDI85905.1 - 1.2e-10 40.4 0.1 0.00026 19.5 0.0 2.7 3 0 0 3 3 3 2 AMP-binding enzyme tRNA-synt_2b PF00587.20 CDI85906.1 - 3.9e-32 111.1 0.0 6e-32 110.5 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) WD40 PF00400.27 CDI85907.1 - 4.4e-18 64.4 2.6 2.4e-06 27.1 0.3 5.2 5 0 0 5 5 5 3 WD domain, G-beta repeat DHC_N2 PF08393.8 CDI85908.1 - 3.3e-107 358.5 6.0 3.3e-107 358.5 4.1 4.6 5 1 1 6 6 6 2 Dynein heavy chain, N-terminal region 2 AAA_6 PF12774.2 CDI85908.1 - 1.9e-95 318.7 0.2 3.4e-95 317.9 0.1 1.4 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region D1 DHC_N1 PF08385.7 CDI85908.1 - 1.9e-95 320.4 2.9 6.9e-95 318.5 2.0 2.0 1 0 0 1 1 1 1 Dynein heavy chain, N-terminal region 1 AAA_7 PF12775.2 CDI85908.1 - 5.5e-50 169.9 0.0 6.6e-48 163.1 0.0 2.6 2 0 0 2 2 2 1 P-loop containing dynein motor region D3 AAA_5 PF07728.9 CDI85908.1 - 3.8e-22 78.5 0.3 2.8e-05 23.8 0.0 5.6 5 1 0 5 5 5 3 AAA domain (dynein-related subfamily) AAA_8 PF12780.2 CDI85908.1 - 3.8e-12 45.7 0.1 9.8e-12 44.4 0.0 1.8 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_22 PF13401.1 CDI85908.1 - 1.5e-07 31.6 0.7 0.75 9.9 0.0 5.2 4 0 0 4 4 4 2 AAA domain AAA PF00004.24 CDI85908.1 - 1.4e-05 25.3 0.1 0.16 12.2 0.0 4.2 4 0 0 4 4 3 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 CDI85908.1 - 0.0013 19.0 0.6 3.7 7.8 0.0 4.4 3 0 0 3 3 3 1 AAA domain AAA_19 PF13245.1 CDI85908.1 - 0.0016 18.1 2.1 0.81 9.4 0.1 3.6 3 0 0 3 3 3 1 Part of AAA domain Sigma54_activat PF00158.21 CDI85908.1 - 0.0033 16.9 0.1 3.7 6.9 0.0 3.1 3 0 0 3 3 3 1 Sigma-54 interaction domain FtsK_SpoIIIE PF01580.13 CDI85908.1 - 0.0035 16.8 0.2 0.26 10.7 0.0 3.3 3 0 0 3 3 3 1 FtsK/SpoIIIE family AAA_28 PF13521.1 CDI85908.1 - 0.0098 15.8 0.0 1.9 8.4 0.0 3.0 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.1 CDI85908.1 - 0.014 14.9 3.5 1.5 8.3 0.1 3.4 4 0 0 4 4 4 0 AAA domain AAA_25 PF13481.1 CDI85908.1 - 0.014 14.7 4.3 1.5 8.2 0.0 4.6 5 0 0 5 5 5 0 AAA domain RNA_helicase PF00910.17 CDI85908.1 - 0.018 15.2 0.5 14 5.8 0.0 4.2 4 0 0 4 4 4 0 RNA helicase DUF853 PF05872.7 CDI85908.1 - 0.038 12.3 2.1 0.66 8.2 0.1 2.4 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF853) AAA_17 PF13207.1 CDI85908.1 - 0.045 14.5 8.5 2 9.2 0.0 4.7 5 0 0 5 5 3 0 AAA domain DUF258 PF03193.11 CDI85908.1 - 0.057 12.6 0.4 0.76 8.9 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function, DUF258 Dynein_heavy PF03028.10 CDI85909.1 - 2.7e-209 696.7 0.0 1.7e-208 694.1 0.0 2.3 2 1 0 2 2 2 1 Dynein heavy chain and region D6 of dynein motor AAA_9 PF12781.2 CDI85909.1 - 8.8e-54 181.7 0.6 1.5e-53 180.9 0.4 1.4 1 0 0 1 1 1 1 ATP-binding dynein motor region D5 MT PF12777.2 CDI85909.1 - 2.2e-52 177.9 9.4 5e-52 176.7 6.5 1.5 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_8 PF12780.2 CDI85909.1 - 1.8e-35 122.2 0.0 4.3e-35 120.9 0.0 1.7 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 Reo_sigmaC PF04582.7 CDI85909.1 - 0.21 10.7 9.8 0.57 9.3 1.2 2.7 3 0 0 3 3 3 0 Reovirus sigma C capsid protein FGF-BP1 PF06473.7 CDI85909.1 - 0.67 9.5 6.0 1.4 8.4 4.1 1.4 1 0 0 1 1 1 0 FGF binding protein 1 (FGF-BP1) Gastrin PF00918.12 CDI85911.1 - 1.1 10.0 3.5 24 5.7 2.0 2.8 2 1 0 2 2 2 0 Gastrin/cholecystokinin family Plasmodium_Vir PF05795.6 CDI85911.1 - 3.2 6.8 5.3 5.4 6.1 3.7 1.3 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Ran_BP1 PF00638.13 CDI85912.1 - 2.8e-05 24.1 1.1 2.8e-05 24.1 0.8 2.0 2 1 0 2 2 2 1 RanBP1 domain CHDCT2 PF08074.6 CDI85912.1 - 0.45 10.2 3.3 0.52 10.0 2.3 1.1 1 0 0 1 1 1 0 CHDCT2 (NUC038) domain CPSF100_C PF13299.1 CDI85912.1 - 2 8.6 8.1 2.1 8.4 5.6 1.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal DHHW PF14286.1 CDI85912.1 - 2.2 7.4 11.7 2.6 7.2 8.1 1.0 1 0 0 1 1 1 0 DHHW protein Pes-10 PF07149.6 CDI85912.1 - 2.3 6.9 7.9 2.6 6.7 5.5 1.1 1 0 0 1 1 1 0 Pes-10 DUF2201_N PF13203.1 CDI85912.1 - 2.8 7.0 10.1 2.7 7.0 7.0 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain Polyoma_lg_T_C PF06431.6 CDI85912.1 - 3.4 6.2 4.9 3.6 6.1 3.4 1.2 1 0 0 1 1 1 0 Polyomavirus large T antigen C-terminus DDHD PF02862.12 CDI85912.1 - 5.4 6.7 15.5 6 6.6 10.7 1.0 1 0 0 1 1 1 0 DDHD domain DUF1510 PF07423.6 CDI85912.1 - 5.7 6.2 20.6 6.3 6.0 14.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Raftlin PF15250.1 CDI85912.1 - 6.5 5.1 10.9 6.8 5.0 7.6 1.0 1 0 0 1 1 1 0 Raftlin CDC45 PF02724.9 CDI85912.1 - 9 4.1 14.4 9.6 4.0 10.0 1.0 1 0 0 1 1 1 0 CDC45-like protein RP-C_C PF11800.3 CDI85912.1 - 9.5 5.8 10.0 11 5.6 6.9 1.2 1 0 0 1 1 1 0 Replication protein C C-terminal region Spore_coat_CotO PF14153.1 CDI85914.1 - 0.27 10.6 0.0 0.27 10.6 0.0 3.1 3 0 0 3 3 3 0 Spore coat protein CotO SPX PF03105.14 CDI85914.1 - 8.6 6.0 30.0 0.94 9.1 0.1 2.3 2 0 0 2 2 2 0 SPX domain DUF679 PF05078.7 CDI85916.1 - 0.084 12.5 0.0 0.38 10.3 0.0 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF679) SR-25 PF10500.4 CDI85917.1 - 0.0003 20.3 13.0 0.0003 20.3 9.0 3.2 2 1 1 3 3 3 2 Nuclear RNA-splicing-associated protein BAF1_ABF1 PF04684.8 CDI85917.1 - 0.0023 16.8 19.1 0.0023 16.8 13.3 2.9 2 1 1 3 3 3 1 BAF1 / ABF1 chromatin reorganising factor Ashwin PF15323.1 CDI85917.1 - 0.011 15.8 24.4 0.22 11.4 11.8 2.1 2 0 0 2 2 2 0 Developmental protein Ribosomal_60s PF00428.14 CDI85917.1 - 0.016 15.6 5.7 0.016 15.6 3.9 3.4 2 1 1 3 3 3 0 60s Acidic ribosomal protein Period_C PF12114.3 CDI85917.1 - 0.63 9.6 33.1 0.92 9.0 14.5 2.4 2 0 0 2 2 2 0 Period protein 2/3C-terminal region DivIC PF04977.10 CDI85917.1 - 4.6 6.7 11.4 9.1 5.8 7.9 1.4 1 0 0 1 1 1 0 Septum formation initiator EF-hand_1 PF00036.27 CDI85918.1 - 0.00022 20.3 0.0 0.00034 19.7 0.0 1.3 1 0 0 1 1 1 1 EF hand EF-hand_5 PF13202.1 CDI85918.1 - 0.00085 18.5 0.0 0.0013 17.9 0.0 1.3 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.1 CDI85918.1 - 0.0027 17.4 0.0 0.0051 16.5 0.0 1.3 1 0 0 1 1 1 1 EF-hand domain EF-hand_8 PF13833.1 CDI85918.1 - 0.055 13.0 0.0 0.085 12.4 0.0 1.3 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_7 PF13499.1 CDI85918.1 - 0.11 12.6 0.0 0.19 11.9 0.0 1.3 1 0 0 1 1 1 0 EF-hand domain pair DUF1183 PF06682.7 CDI85918.1 - 0.13 11.8 10.1 0.017 14.7 4.0 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1183) Sporozoite_P67 PF05642.6 CDI85918.1 - 1.2 6.8 15.8 1.9 6.2 10.9 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen ABC2_membrane_3 PF12698.2 CDI85918.1 - 7.9 5.3 7.0 14 4.5 4.9 1.4 1 0 0 1 1 1 0 ABC-2 family transporter protein Neur_chan_memb PF02932.11 CDI85918.1 - 8.7 6.1 7.3 19 5.0 5.0 1.7 1 1 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Macoilin PF09726.4 CDI85919.1 - 0.025 12.9 39.1 0.032 12.5 27.1 1.1 1 0 0 1 1 1 0 Transmembrane protein Ycf1 PF05758.7 CDI85919.1 - 1.7 6.2 25.3 2.5 5.7 17.5 1.2 1 0 0 1 1 1 0 Ycf1 DUF1510 PF07423.6 CDI85919.1 - 2 7.7 33.6 0.21 10.9 18.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) DUF912 PF06024.7 CDI85920.1 - 0.0084 16.1 5.7 0.0084 16.1 3.9 2.1 1 1 1 2 2 2 1 Nucleopolyhedrovirus protein of unknown function (DUF912) OAD_gamma PF04277.8 CDI85920.1 - 0.011 16.0 1.3 0.58 10.5 0.1 2.1 1 1 1 2 2 2 0 Oxaloacetate decarboxylase, gamma chain Peroxin-13_N PF04088.8 CDI85920.1 - 0.012 15.5 6.7 0.012 15.5 4.7 2.0 1 1 1 2 2 2 0 Peroxin 13, N-terminal region DUF3357 PF11837.3 CDI85920.1 - 0.014 15.2 9.2 0.26 11.1 0.6 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF3357) PBP1_TM PF14812.1 CDI85920.1 - 0.16 12.2 12.6 0.68 10.2 2.0 2.2 1 1 1 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal GRP PF07172.6 CDI85920.1 - 0.18 12.2 12.5 1.5 9.3 1.8 2.1 1 1 1 2 2 2 0 Glycine rich protein family SpoIIIAH PF12685.2 CDI85920.1 - 0.19 11.2 17.5 0.42 10.0 3.1 2.0 1 1 1 2 2 2 0 SpoIIIAH-like protein Conotoxin PF02950.12 CDI85920.1 - 0.36 11.6 22.0 1.5 9.6 3.4 2.3 1 1 1 2 2 2 0 Conotoxin DUF1510 PF07423.6 CDI85920.1 - 0.49 9.7 25.1 1.3 8.3 17.4 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1510) DUF843 PF05814.6 CDI85920.1 - 1.1 9.1 8.1 1.7 8.4 1.0 2.2 1 1 1 2 2 2 0 Baculovirus protein of unknown function (DUF843) Rtf2 PF04641.7 CDI85920.1 - 1.2 8.3 20.3 1.7 7.7 14.0 1.2 1 0 0 1 1 1 0 Rtf2 RING-finger Herpes_UL87 PF03043.9 CDI85920.1 - 2.1 6.6 16.0 2.2 6.5 11.1 1.0 1 0 0 1 1 1 0 Herpesvirus UL87 family DUF2782 PF11191.3 CDI85920.1 - 2.3 8.2 13.3 3.5 7.6 1.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2782) Stig1 PF04885.8 CDI85920.1 - 3.3 7.8 16.0 4.1 7.5 3.4 2.0 1 1 1 2 2 2 0 Stigma-specific protein, Stig1 Neur_chan_memb PF02932.11 CDI85920.1 - 3.5 7.4 21.1 4.3 7.1 14.6 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF4366 PF14283.1 CDI85920.1 - 5.1 6.4 15.5 38 3.5 11.2 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4366) DUF819 PF05684.7 CDI85920.1 - 6.4 5.4 8.3 6.8 5.3 0.7 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF819) DUF2615 PF11027.3 CDI85920.1 - 6.5 6.7 17.9 20 5.1 12.3 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2615) Scs3p PF10261.4 CDI85920.1 - 8.5 5.3 16.5 13 4.7 11.0 1.6 1 1 0 1 1 1 0 Inositol phospholipid synthesis and fat-storage-inducing TM Ycf1 PF05758.7 CDI85920.1 - 9.6 3.7 22.7 10 3.6 15.7 1.0 1 0 0 1 1 1 0 Ycf1 PrmA PF06325.8 CDI85921.1 - 2.6e-08 33.3 0.3 2.6e-08 33.3 0.2 3.4 3 1 0 3 3 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.1 CDI85921.1 - 1.2e-06 28.1 0.3 1.2e-06 28.1 0.2 3.2 2 2 0 2 2 1 1 Methyltransferase domain MTS PF05175.9 CDI85921.1 - 5e-06 26.0 0.0 5e-06 26.0 0.0 3.1 3 1 0 3 3 1 1 Methyltransferase small domain Methyltransf_18 PF12847.2 CDI85921.1 - 1.3e-05 25.7 8.6 1.3e-05 25.7 5.9 3.7 3 1 0 3 3 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 CDI85921.1 - 0.00011 21.9 0.0 0.00011 21.9 0.0 3.8 2 2 0 2 2 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CDI85921.1 - 0.00024 21.5 8.3 0.00056 20.3 0.0 4.3 2 2 1 4 4 4 1 Methyltransferase domain FimP PF09766.4 CDI85921.1 - 0.0015 17.6 0.4 0.0015 17.6 0.3 4.1 4 0 0 4 4 4 3 Fms-interacting protein Methyltransf_12 PF08242.7 CDI85921.1 - 0.047 14.1 0.1 0.047 14.1 0.0 4.5 3 2 1 4 4 4 0 Methyltransferase domain TehB PF03848.9 CDI85921.1 - 0.088 11.9 0.0 0.17 11.0 0.0 1.4 1 0 0 1 1 1 0 Tellurite resistance protein TehB Ubie_methyltran PF01209.13 CDI85921.1 - 0.12 11.5 0.0 0.21 10.6 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Peptidase_S49_N PF08496.5 CDI85921.1 - 0.14 11.9 0.1 0.14 11.9 0.0 4.1 4 1 1 5 5 3 0 Peptidase family S49 N-terminal Methyltransf_9 PF08003.6 CDI85921.1 - 0.26 9.9 0.0 0.26 9.9 0.0 2.8 3 1 0 3 3 2 0 Protein of unknown function (DUF1698) RCR PF12273.3 CDI85921.1 - 2.4 8.7 38.7 0.025 15.1 13.3 3.5 3 0 0 3 3 3 0 Chitin synthesis regulation, resistance to Congo red RNA_lig_T4_1 PF09511.5 CDI85921.1 - 4.5 6.6 9.3 24 4.2 3.8 2.7 2 1 0 2 2 2 0 RNA ligase zf-HIT PF04438.11 CDI85922.1 - 0.0021 17.6 17.8 0.0021 17.6 12.4 1.5 2 0 0 2 2 2 1 HIT zinc finger UPF0564 PF10595.4 CDI85923.1 - 0.0026 16.7 40.3 0.041 12.7 17.2 2.3 2 0 0 2 2 2 2 Uncharacterised protein family UPF0564 DUF1510 PF07423.6 CDI85923.1 - 0.11 11.8 28.8 0.21 10.9 11.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) Ribosomal_60s PF00428.14 CDI85923.1 - 0.19 12.1 7.4 0.84 10.0 5.1 2.1 1 0 0 1 1 1 0 60s Acidic ribosomal protein Raftlin PF15250.1 CDI85923.1 - 0.27 9.7 25.0 0.49 8.8 2.8 2.2 2 0 0 2 2 2 0 Raftlin Herpes_UL87 PF03043.9 CDI85923.1 - 0.31 9.3 20.9 1 7.6 1.6 2.2 2 0 0 2 2 2 0 Herpesvirus UL87 family SGT1 PF07093.6 CDI85923.1 - 0.54 8.5 25.1 0.022 13.1 0.9 2.2 2 0 0 2 2 2 0 SGT1 protein PRP1_N PF06424.7 CDI85923.1 - 0.87 9.9 22.4 0.27 11.5 6.7 2.5 2 0 0 2 2 2 0 PRP1 splicing factor, N-terminal MRP-S31 PF15433.1 CDI85923.1 - 1.1 8.6 36.6 2.8 7.2 14.7 2.2 2 0 0 2 2 2 0 Mitochondrial 28S ribosomal protein S31 DUF4045 PF13254.1 CDI85923.1 - 1.9 7.6 26.0 0.5 9.6 0.3 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4045) AUX_IAA PF02309.11 CDI85923.1 - 2.2 7.9 26.3 3.8 7.1 9.2 2.4 2 0 0 2 2 2 0 AUX/IAA family Band_3_cyto PF07565.8 CDI85923.1 - 2.4 7.5 30.2 0.22 11.0 1.5 2.4 2 0 0 2 2 2 0 Band 3 cytoplasmic domain GAGA_bind PF06217.7 CDI85923.1 - 3.9 7.3 29.9 7 6.5 11.3 2.3 2 0 0 2 2 2 0 GAGA binding protein-like family FLO_LFY PF01698.11 CDI85923.1 - 6.1 5.5 29.1 5 5.8 4.7 2.2 2 0 0 2 2 2 0 Floricaula / Leafy protein Spore_coat_CotO PF14153.1 CDI85923.1 - 7.8 5.9 43.3 0.11 11.8 2.4 2.4 2 0 0 2 2 2 0 Spore coat protein CotO PAT1 PF09770.4 CDI85924.1 - 1.1 7.4 86.0 1.6 6.8 59.6 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 CDK2AP PF09806.4 CDI85925.1 - 0.005 17.0 5.4 0.005 17.0 3.7 4.8 3 2 1 4 4 4 1 Cyclin-dependent kinase 2-associated protein Ribosomal_60s PF00428.14 CDI85925.1 - 0.27 11.6 15.5 0.34 11.3 3.8 2.5 2 0 0 2 2 2 0 60s Acidic ribosomal protein Spt20 PF12090.3 CDI85926.1 - 0.099 11.9 15.9 0.32 10.3 0.1 3.6 4 0 0 4 4 4 0 Spt20 family DUF4199 PF13858.1 CDI85926.1 - 0.58 10.0 4.6 6.4 6.6 0.9 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4199) PAP2 PF01569.16 CDI85926.1 - 0.69 9.5 9.1 2.3 7.9 0.0 3.7 3 1 1 4 4 4 0 PAP2 superfamily TFIIA PF03153.8 CDI85926.1 - 1.4 8.7 43.9 0.034 14.0 15.2 3.6 3 1 0 3 3 3 0 Transcription factor IIA, alpha/beta subunit Pex14_N PF04695.8 CDI85926.1 - 9.3 6.3 36.3 1.7 8.7 0.4 4.6 4 1 0 4 4 4 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Dehydrin PF00257.14 CDI85927.1 - 0.043 14.1 0.8 0.059 13.6 0.5 1.2 1 0 0 1 1 1 0 Dehydrin tRNA_synt_2f PF02092.12 CDI85927.1 - 0.49 8.8 5.0 0.58 8.6 3.5 1.1 1 0 0 1 1 1 0 Glycyl-tRNA synthetase beta subunit PIN_3 PF13470.1 CDI85927.1 - 1.5 9.4 6.3 2.2 8.9 4.4 1.2 1 0 0 1 1 1 0 PIN domain Med15 PF09606.5 CDI85927.1 - 1.5 6.8 12.6 1.6 6.7 8.7 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Draxin PF15550.1 CDI85927.1 - 2.2 7.8 7.5 2.7 7.5 5.2 1.0 1 0 0 1 1 1 0 Draxin DUF3367 PF11847.3 CDI85927.1 - 3.3 5.5 10.9 3.7 5.3 7.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3367) Presenilin PF01080.12 CDI85927.1 - 9.9 4.8 6.1 11 4.6 4.3 1.1 1 0 0 1 1 1 0 Presenilin Sporozoite_P67 PF05642.6 CDI85928.1 - 0.00044 18.2 11.6 0.00058 17.8 8.0 1.1 1 0 0 1 1 1 1 Sporozoite P67 surface antigen DUF1635 PF07795.6 CDI85928.1 - 0.001 18.5 8.5 0.0012 18.2 0.6 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1635) Med15 PF09606.5 CDI85928.1 - 0.0015 16.8 19.3 0.0017 16.6 13.4 1.2 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal Secretin_N_2 PF07655.8 CDI85928.1 - 0.0038 17.5 2.9 0.0038 17.5 2.0 2.3 2 0 0 2 2 2 1 Secretin N-terminal domain FSIP1 PF15554.1 CDI85928.1 - 0.057 12.2 18.6 0.12 11.2 2.4 2.0 2 0 0 2 2 2 0 FSIP1 family FAM60A PF15396.1 CDI85928.1 - 1 9.0 9.5 2.8 7.6 0.4 2.1 2 0 0 2 2 2 0 Protein Family FAM60A PsaN PF05479.6 CDI85928.1 - 2.4 8.1 8.6 0.72 9.8 3.5 1.9 2 0 0 2 2 2 0 Photosystem I reaction centre subunit N (PSAN or PSI-N) Neur_chan_memb PF02932.11 CDI85928.1 - 3.9 7.3 9.6 7 6.4 6.6 1.4 1 1 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region SR-25 PF10500.4 CDI85928.1 - 4.4 6.7 30.4 1.8 7.9 12.1 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein MFMR PF07777.6 CDI85928.1 - 7.6 6.4 13.5 1.3 8.8 5.2 2.0 2 0 0 2 2 2 0 G-box binding protein MFMR TPR_11 PF13414.1 CDI85929.1 - 3.7e-11 42.4 10.2 3.4e-06 26.6 1.1 3.7 3 0 0 3 3 3 3 TPR repeat TPR_2 PF07719.12 CDI85929.1 - 2.7e-09 36.2 9.7 0.013 15.3 1.2 4.9 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.1 CDI85929.1 - 2.9e-07 30.5 16.9 0.00087 19.7 0.1 6.2 4 1 2 6 6 5 4 Tetratricopeptide repeat TPR_16 PF13432.1 CDI85929.1 - 6.1e-06 26.7 33.4 0.00016 22.2 7.6 5.9 3 2 1 5 5 4 2 Tetratricopeptide repeat TPR_1 PF00515.23 CDI85929.1 - 4.6e-05 22.8 2.5 0.21 11.2 0.2 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.1 CDI85929.1 - 0.00025 20.6 0.0 0.71 9.7 0.1 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 CDI85929.1 - 0.0003 20.6 11.3 0.74 9.7 1.5 3.9 2 1 1 3 3 3 3 Tetratricopeptide repeat SR-25 PF10500.4 CDI85929.1 - 0.0015 18.0 15.1 0.1 12.0 2.6 2.4 2 0 0 2 2 2 2 Nuclear RNA-splicing-associated protein TPR_9 PF13371.1 CDI85929.1 - 0.0035 17.1 3.0 0.0035 17.1 2.1 4.4 4 2 2 6 6 5 1 Tetratricopeptide repeat TPR_17 PF13431.1 CDI85929.1 - 0.11 12.7 7.1 0.31 11.3 0.0 4.0 4 0 0 4 4 3 0 Tetratricopeptide repeat OrfB_Zn_ribbon PF07282.6 CDI85929.1 - 0.12 12.0 0.2 0.25 11.0 0.1 1.5 1 0 0 1 1 1 0 Putative transposase DNA-binding domain PAT1 PF09770.4 CDI85929.1 - 0.24 9.6 17.2 0.32 9.1 11.9 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TPR_6 PF13174.1 CDI85929.1 - 1.3 9.6 0.0 1.3 9.6 0.0 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat SOG2 PF10428.4 CDI85929.1 - 3.3 6.2 13.6 0.071 11.7 5.0 1.5 2 0 0 2 2 2 0 RAM signalling pathway protein AMH_N PF04709.7 CDI85931.1 - 0.017 14.0 1.5 0.026 13.4 1.1 1.2 1 0 0 1 1 1 0 Anti-Mullerian hormone, N terminal region AAA_16 PF13191.1 CDI85932.1 - 9.3e-07 29.0 0.0 1e-06 28.8 0.0 1.1 1 0 0 1 1 1 1 AAA ATPase domain Arch_ATPase PF01637.13 CDI85932.1 - 0.00011 22.0 0.0 0.00012 21.8 0.0 1.1 1 0 0 1 1 1 1 Archaeal ATPase AAA_5 PF07728.9 CDI85932.1 - 0.0025 17.5 0.0 0.0055 16.4 0.0 1.5 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA PF00004.24 CDI85932.1 - 0.0072 16.5 0.0 0.013 15.6 0.0 1.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 CDI85932.1 - 0.02 15.0 0.0 0.024 14.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 CDI85932.1 - 0.035 14.2 0.0 0.049 13.7 0.0 1.3 1 0 0 1 1 1 0 RNA helicase DUF258 PF03193.11 CDI85932.1 - 0.039 13.1 0.0 0.045 12.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_18 PF13238.1 CDI85932.1 - 0.058 13.6 0.0 0.082 13.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.8 CDI85932.1 - 0.082 11.6 0.0 0.082 11.6 0.0 1.1 1 0 0 1 1 1 0 TIP49 C-terminus NACHT PF05729.7 CDI85932.1 - 0.089 12.4 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 NACHT domain AAA_19 PF13245.1 CDI85932.1 - 0.11 12.2 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 Part of AAA domain RskA PF10099.4 CDI85933.1 - 0.016 14.9 4.9 0.022 14.4 3.4 1.2 1 0 0 1 1 1 0 Anti-sigma-K factor rskA PsbQ PF05757.6 CDI85933.1 - 0.2 11.0 4.5 0.28 10.5 3.1 1.2 1 0 0 1 1 1 0 Oxygen evolving enhancer protein 3 (PsbQ) Menin PF05053.8 CDI85933.1 - 0.29 9.2 1.3 0.29 9.2 0.9 1.1 1 0 0 1 1 1 0 Menin PsbW PF07123.7 CDI85933.1 - 1.1 9.3 4.3 1.5 8.8 3.0 1.2 1 0 0 1 1 1 0 Photosystem II reaction centre W protein (PsbW) BAF1_ABF1 PF04684.8 CDI85934.1 - 0.00011 21.2 33.4 0.00011 21.2 23.2 4.1 2 2 2 4 4 4 1 BAF1 / ABF1 chromatin reorganising factor FimP PF09766.4 CDI85936.1 - 0.0097 15.0 6.0 0.0097 15.0 4.2 2.1 2 0 0 2 2 2 2 Fms-interacting protein Tim54 PF11711.3 CDI85936.1 - 0.87 8.1 13.2 0.49 8.9 3.7 2.3 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 Band_3_cyto PF07565.8 CDI85936.1 - 1.8 8.0 12.9 2.6 7.4 2.9 2.4 2 0 0 2 2 2 0 Band 3 cytoplasmic domain Suf PF05843.9 CDI85936.1 - 2 8.0 24.4 0.57 9.8 8.2 2.4 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) FimP PF09766.4 CDI85937.1 - 0.0038 16.3 4.1 0.0038 16.3 2.8 3.1 2 1 0 2 2 2 1 Fms-interacting protein Suf PF05843.9 CDI85937.1 - 0.0053 16.5 0.8 0.0053 16.5 0.6 2.6 2 1 0 2 2 2 1 Suppressor of forked protein (Suf) Spt20 PF12090.3 CDI85937.1 - 0.0053 16.1 0.3 0.0053 16.1 0.2 3.2 2 1 0 2 2 2 1 Spt20 family Activator_LAG-3 PF11498.3 CDI85937.1 - 0.0066 15.2 15.9 0.0066 15.2 11.0 2.6 2 1 0 2 2 2 1 Transcriptional activator LAG-3 AAA_23 PF13476.1 CDI85937.1 - 0.1 12.8 0.2 0.1 12.8 0.2 2.2 2 0 0 2 2 2 0 AAA domain PAT1 PF09770.4 CDI85937.1 - 0.19 9.9 41.8 0.24 9.6 14.6 2.2 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 Med15 PF09606.5 CDI85937.1 - 0.72 7.9 67.2 0.8 7.8 13.2 2.1 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal FAM176 PF14851.1 CDI85937.1 - 1.5 8.5 11.8 1.5 8.5 0.7 2.4 2 0 0 2 2 2 0 FAM176 family Spc7_N PF15402.1 CDI85937.1 - 2.8 5.8 26.1 0.46 8.4 10.9 2.0 2 0 0 2 2 2 0 N-terminus of kinetochore NMS complex subunit Spc7 DUF4652 PF15525.1 CDI85937.1 - 8.1 5.8 12.1 0.22 10.9 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4652) Aconitase_C PF00694.14 CDI85938.1 - 0.0093 16.0 28.0 0.038 14.0 4.8 2.3 1 1 1 2 2 2 2 Aconitase C-terminal domain MIP-T3 PF10243.4 CDI85938.1 - 1.2 7.5 74.2 1.4 7.2 51.5 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 RCC1 PF00415.13 CDI85939.1 - 8.5e-17 61.1 10.2 9.6e-07 28.9 0.6 3.9 3 1 0 3 3 3 3 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 CDI85939.1 - 0.006 16.1 14.9 0.11 12.1 2.1 3.9 3 0 0 3 3 3 2 Regulator of chromosome condensation (RCC1) repeat Miff PF05644.6 CDI85939.1 - 3.8 7.0 25.6 0.045 13.3 7.7 2.9 2 1 1 3 3 3 0 Mitochondrial and peroxisomal fission factor Mff Vfa1 PF08432.5 CDI85940.1 - 0.0089 16.0 21.6 0.0089 16.0 15.0 3.7 4 0 0 4 4 4 2 AAA-ATPase Vps4-associated protein 1 DUF3801 PF12687.2 CDI85940.1 - 0.012 15.1 0.7 0.012 15.1 0.5 4.1 3 1 0 3 3 3 0 Protein of unknown function (DUF3801) CDC45 PF02724.9 CDI85940.1 - 0.055 11.5 49.8 0.3 9.0 17.2 3.3 3 0 0 3 3 3 0 CDC45-like protein CD20 PF04103.10 CDI85940.1 - 0.13 12.2 0.1 0.13 12.2 0.1 4.6 3 2 0 3 3 3 0 CD20-like family SGT1 PF07093.6 CDI85940.1 - 0.19 10.1 48.2 0.69 8.2 13.2 2.1 2 0 0 2 2 2 0 SGT1 protein Plasmodium_Vir PF05795.6 CDI85940.1 - 1.3 8.1 31.1 0.45 9.6 5.1 3.3 3 0 0 3 3 3 0 Plasmodium vivax Vir protein SAPS PF04499.10 CDI85940.1 - 1.6 7.3 50.2 0.26 9.8 12.4 3.2 3 0 0 3 3 3 0 SIT4 phosphatase-associated protein Endostatin PF06482.6 CDI85940.1 - 8.5 5.6 36.7 0.48 9.7 10.4 3.4 3 0 0 3 3 3 0 Collagenase NC10 and Endostatin SR-25 PF10500.4 CDI85941.1 - 0.0008 18.9 17.6 0.0008 18.9 12.2 3.2 2 1 1 3 3 3 2 Nuclear RNA-splicing-associated protein Queuosine_synth PF02547.10 CDI85941.1 - 0.056 12.1 0.1 0.056 12.1 0.1 1.8 2 0 0 2 2 2 0 Queuosine biosynthesis protein U1snRNP70_N PF12220.3 CDI85941.1 - 0.07 13.4 16.0 0.082 13.2 5.0 2.2 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal MACPF PF01823.14 CDI85941.1 - 0.11 12.1 9.9 1.1 8.9 0.2 2.9 2 1 0 2 2 2 0 MAC/Perforin domain PBP1_TM PF14812.1 CDI85941.1 - 0.12 12.6 3.3 16 5.8 0.0 2.3 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF737 PF05300.6 CDI85941.1 - 1.1 9.1 30.1 2.6 7.9 6.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF737) DUF2058 PF09831.4 CDI85941.1 - 1.4 8.7 24.0 1.4 8.8 7.0 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2058) zf-DHHC PF01529.15 CDI85941.1 - 1.5 8.1 7.1 5.5 6.3 0.2 2.2 2 0 0 2 2 2 0 DHHC palmitoyltransferase OmpH PF03938.9 CDI85941.1 - 2.8 7.8 33.5 0.9 9.4 5.2 2.1 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Bud13 PF09736.4 CDI85941.1 - 6.4 7.0 21.1 3.2 7.9 1.1 2.2 2 0 0 2 2 2 0 Pre-mRNA-splicing factor of RES complex Peptidase_S49_N PF08496.5 CDI85941.1 - 6.5 6.5 15.3 3.6 7.3 0.4 2.2 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Period_C PF12114.3 CDI85941.1 - 6.5 6.3 44.3 0.28 10.7 8.3 2.3 2 1 0 2 2 2 0 Period protein 2/3C-terminal region Cellulose_synt PF03552.9 CDI85941.1 - 7.6 4.7 9.5 0.61 8.3 1.1 2.0 2 0 0 2 2 2 0 Cellulose synthase RIC3 PF15361.1 CDI85941.1 - 8.5 6.6 23.4 2.5 8.3 3.4 2.2 2 0 0 2 2 2 0 Resistance to inhibitors of cholinesterase homologue 3 Suf PF05843.9 CDI85942.1 - 0.0066 16.2 7.5 0.0066 16.2 5.2 2.2 2 0 0 2 2 2 1 Suppressor of forked protein (Suf) Folate_carrier PF01770.13 CDI85942.1 - 0.15 10.5 6.1 0.29 9.6 4.2 1.5 1 0 0 1 1 1 0 Reduced folate carrier CDK5_activator PF03261.10 CDI85942.1 - 0.28 10.4 21.0 0.37 10.0 1.2 2.2 2 0 0 2 2 2 0 Cyclin-dependent kinase 5 activator protein zf-DHHC PF01529.15 CDI85942.1 - 1.4 8.3 4.5 0.18 11.1 0.0 1.8 2 0 0 2 2 2 0 DHHC palmitoyltransferase NARP1 PF12569.3 CDI85942.1 - 2.2 6.9 15.8 0.21 10.3 7.6 1.8 2 0 0 2 2 2 0 NMDA receptor-regulated protein 1 DUF2052 PF09747.4 CDI85942.1 - 3.1 7.6 23.0 0.68 9.8 10.0 2.4 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) AUX_IAA PF02309.11 CDI85942.1 - 3.3 7.4 12.9 0.39 10.4 5.2 2.0 2 0 0 2 2 2 0 AUX/IAA family GOLD_2 PF13897.1 CDI85942.1 - 5.3 7.2 5.6 16 5.7 3.9 1.8 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking DUF4011 PF13195.1 CDI85942.1 - 8 6.4 13.2 12 5.8 6.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4011) DDRGK PF09756.4 CDI85943.1 - 0.17 11.2 33.0 0.19 11.1 22.9 1.0 1 0 0 1 1 1 0 DDRGK domain Trypan_PARP PF05887.6 CDI85943.1 - 0.4 10.4 8.6 0.48 10.2 6.0 1.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) BAF1_ABF1 PF04684.8 CDI85943.1 - 0.4 9.4 25.0 0.48 9.2 17.3 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor DUF2058 PF09831.4 CDI85943.1 - 0.79 9.5 25.6 0.85 9.4 17.7 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2058) Pex16 PF08610.5 CDI85943.1 - 1.5 7.7 13.2 1.5 7.7 9.1 1.0 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) MIP-T3 PF10243.4 CDI85943.1 - 2 6.7 33.0 2.1 6.7 22.8 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Vfa1 PF08432.5 CDI85943.1 - 2.4 8.1 20.9 2.8 7.9 14.5 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF4045 PF13254.1 CDI85943.1 - 2.5 7.3 18.9 2.8 7.1 13.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Pox_Ag35 PF03286.9 CDI85943.1 - 2.6 7.4 17.6 3.2 7.2 12.2 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein UPF0560 PF10577.4 CDI85943.1 - 3 5.9 16.1 3.5 5.7 11.2 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 DUF1510 PF07423.6 CDI85943.1 - 3.4 6.9 23.7 3.9 6.7 16.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) CobT PF06213.7 CDI85943.1 - 4.3 6.3 19.8 5.1 6.1 13.7 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT VID27 PF08553.5 CDI85943.1 - 4.5 5.3 14.0 4.6 5.3 9.7 1.0 1 0 0 1 1 1 0 VID27 cytoplasmic protein CDC45 PF02724.9 CDI85943.1 - 4.7 5.1 23.1 5 5.0 16.0 1.0 1 0 0 1 1 1 0 CDC45-like protein Asp-B-Hydro_N PF05279.6 CDI85943.1 - 5.1 6.8 22.1 5.8 6.6 15.3 1.0 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Gti1_Pac2 PF09729.4 CDI85943.1 - 5.9 6.7 12.6 7.1 6.4 8.7 1.2 1 0 0 1 1 1 0 Gti1/Pac2 family Daxx PF03344.10 CDI85943.1 - 7.1 4.9 21.1 7.4 4.9 14.6 1.0 1 0 0 1 1 1 0 Daxx Family Folate_carrier PF01770.13 CDI85943.1 - 7.1 5.0 10.7 7.7 4.9 7.4 1.1 1 0 0 1 1 1 0 Reduced folate carrier Tim54 PF11711.3 CDI85943.1 - 7.7 4.9 15.5 8.5 4.8 10.7 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Pal1 PF08316.6 CDI85943.1 - 7.8 6.9 8.3 9.5 6.6 5.8 1.2 1 0 0 1 1 1 0 Pal1 cell morphology protein FAM60A PF15396.1 CDI85943.1 - 8.7 6.0 14.2 9.3 5.9 9.8 1.1 1 0 0 1 1 1 0 Protein Family FAM60A Zip PF02535.17 CDI85943.1 - 9.4 5.1 13.7 9.9 5.0 9.5 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter NOA36 PF06524.7 CDI85944.1 - 0.0012 18.1 0.7 0.0013 18.0 0.5 1.1 1 0 0 1 1 1 1 NOA36 protein Sporozoite_P67 PF05642.6 CDI85944.1 - 0.0026 15.7 3.9 0.0028 15.6 2.7 1.0 1 0 0 1 1 1 1 Sporozoite P67 surface antigen CDC45 PF02724.9 CDI85944.1 - 0.0029 15.7 2.2 0.003 15.6 1.5 1.0 1 0 0 1 1 1 1 CDC45-like protein DUF1712 PF08217.6 CDI85944.1 - 0.015 13.5 4.3 0.017 13.3 3.0 1.0 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1712) Peptidase_C12 PF01088.16 CDI85944.1 - 0.068 12.3 1.8 0.74 8.9 0.0 2.0 2 0 0 2 2 2 0 Ubiquitin carboxyl-terminal hydrolase, family 1 CDK2AP PF09806.4 CDI85944.1 - 0.15 12.3 8.4 0.2 11.9 5.8 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein AF-4 PF05110.8 CDI85944.1 - 0.22 9.3 21.7 0.28 8.9 15.1 1.2 1 0 0 1 1 1 0 AF-4 proto-oncoprotein DUF572 PF04502.8 CDI85944.1 - 0.57 9.3 8.5 0.72 9.0 5.9 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Transposase_24 PF03004.9 CDI85944.1 - 0.58 10.0 6.6 0.75 9.6 4.6 1.1 1 0 0 1 1 1 0 Plant transposase (Ptta/En/Spm family) DUF3774 PF12609.3 CDI85944.1 - 2.1 9.2 11.1 2.2 9.1 4.7 2.3 2 0 0 2 2 2 0 Wound-induced protein DNA_pol_viral_N PF00242.12 CDI85944.1 - 2.6 6.9 11.8 3.3 6.6 8.2 1.1 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain NPR3 PF03666.8 CDI85944.1 - 5.3 5.4 10.0 6.6 5.1 6.9 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 BUD22 PF09073.5 CDI85944.1 - 9.2 5.2 18.7 13 4.6 13.0 1.2 1 0 0 1 1 1 0 BUD22 DUF936 PF06075.7 CDI85945.1 - 0.0084 15.0 26.0 0.0092 14.9 18.0 1.0 1 0 0 1 1 1 1 Plant protein of unknown function (DUF936) BBS2_C PF14782.1 CDI85945.1 - 0.049 12.2 7.2 0.055 12.0 5.0 1.0 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, C-terminal Draxin PF15550.1 CDI85945.1 - 0.066 12.8 10.8 0.072 12.7 7.5 1.2 1 0 0 1 1 1 0 Draxin DUF4647 PF15504.1 CDI85945.1 - 0.28 9.9 16.6 0.34 9.6 11.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4647) DUF572 PF04502.8 CDI85945.1 - 0.39 9.8 22.8 0.46 9.6 15.8 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Spc7_N PF15402.1 CDI85945.1 - 0.52 8.2 33.3 0.63 7.9 23.1 1.0 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 PVL_ORF50 PF07768.6 CDI85945.1 - 0.63 10.0 6.8 0.82 9.6 4.7 1.2 1 0 0 1 1 1 0 PVL ORF-50-like family Daxx PF03344.10 CDI85945.1 - 4.4 5.6 21.0 5.2 5.4 14.6 1.0 1 0 0 1 1 1 0 Daxx Family Utp14 PF04615.8 CDI85945.1 - 4.8 5.2 17.1 5.5 5.0 11.9 1.0 1 0 0 1 1 1 0 Utp14 protein DUF4175 PF13779.1 CDI85945.1 - 6.8 4.2 18.2 8.4 3.9 12.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Na_trans_assoc PF06512.8 CDI85945.1 - 8.9 6.2 14.1 13 5.7 9.8 1.2 1 0 0 1 1 1 0 Sodium ion transport-associated SDA1 PF05285.7 CDI85950.1 - 0.00017 20.9 4.2 0.00023 20.5 2.9 1.2 1 0 0 1 1 1 1 SDA1 BAF1_ABF1 PF04684.8 CDI85950.1 - 0.0014 17.6 19.7 0.0014 17.6 13.7 2.2 2 0 0 2 2 1 1 BAF1 / ABF1 chromatin reorganising factor GPCR_chapero_1 PF11904.3 CDI85950.1 - 0.15 11.2 7.3 0.2 10.7 5.1 1.2 1 0 0 1 1 1 0 GPCR-chaperone SGT1 PF07093.6 CDI85950.1 - 0.53 8.5 14.0 0.31 9.3 3.3 2.0 2 0 0 2 2 2 0 SGT1 protein Gti1_Pac2 PF09729.4 CDI85950.1 - 0.71 9.7 8.2 0.13 12.1 1.6 2.1 2 0 0 2 2 2 0 Gti1/Pac2 family CDC45 PF02724.9 CDI85950.1 - 0.96 7.4 11.2 0.12 10.3 3.8 1.9 2 0 0 2 2 2 0 CDC45-like protein Zip PF02535.17 CDI85950.1 - 1 8.3 4.6 1.8 7.4 3.2 1.5 1 1 0 1 1 1 0 ZIP Zinc transporter FAM60A PF15396.1 CDI85950.1 - 1.2 8.8 5.8 0.27 10.9 0.5 2.0 2 0 0 2 2 2 0 Protein Family FAM60A DUF3807 PF12720.2 CDI85950.1 - 2.1 8.5 20.6 0.042 14.0 6.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3807) Mem_trans PF03547.13 CDI85950.1 - 4.3 5.5 7.9 0.15 10.3 1.0 1.8 1 1 1 2 2 2 0 Membrane transport protein SelP_N PF04592.9 CDI85950.1 - 4.4 6.6 14.1 9.1 5.5 9.8 1.5 1 1 0 1 1 1 0 Selenoprotein P, N terminal region DUF572 PF04502.8 CDI85950.1 - 5.5 6.1 18.3 0.11 11.7 4.6 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF572) OATP PF03137.15 CDI85950.1 - 6.4 4.6 12.4 5.9 4.8 4.3 2.3 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family DUF755 PF05501.6 CDI85952.1 - 0.00055 19.9 10.5 0.00055 19.9 7.3 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF755) BLVR PF06375.6 CDI85952.1 - 0.0021 17.8 5.0 0.003 17.3 0.8 2.1 2 0 0 2 2 2 1 Bovine leukaemia virus receptor (BLVR) SR-25 PF10500.4 CDI85952.1 - 0.012 15.0 9.4 0.012 15.0 6.5 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Thymidylate_kin PF02223.12 CDI85952.1 - 0.014 14.7 7.0 0.015 14.6 0.7 2.3 2 0 0 2 2 2 0 Thymidylate kinase U1snRNP70_N PF12220.3 CDI85952.1 - 0.015 15.6 15.7 0.19 12.0 1.4 2.5 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal Ribosomal_60s PF00428.14 CDI85952.1 - 0.021 15.2 9.2 0.021 15.2 6.4 3.7 3 1 1 4 4 1 0 60s Acidic ribosomal protein Neuro_bHLH PF12533.3 CDI85952.1 - 0.022 15.5 17.3 0.24 12.2 3.4 2.2 2 0 0 2 2 2 0 Neuronal helix-loop-helix transcription factor FimP PF09766.4 CDI85952.1 - 0.049 12.6 23.2 0.41 9.6 6.9 2.1 2 0 0 2 2 2 0 Fms-interacting protein DUF4647 PF15504.1 CDI85952.1 - 0.054 12.3 16.8 0.052 12.4 3.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4647) Peptidase_S49_N PF08496.5 CDI85952.1 - 0.12 12.1 14.4 0.14 11.9 4.0 2.3 2 0 0 2 2 2 0 Peptidase family S49 N-terminal DUF3853 PF12964.2 CDI85952.1 - 0.14 11.9 6.4 0.45 10.3 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3853) Isy1 PF06246.7 CDI85952.1 - 0.16 11.3 12.5 0.083 12.2 0.3 2.1 2 0 0 2 2 2 0 Isy1-like splicing family ATAD4 PF15321.1 CDI85952.1 - 0.22 12.5 10.5 2.4 9.1 2.1 2.5 2 0 0 2 2 2 0 ATPase family AAA domain containing 4 DUF3371 PF11851.3 CDI85952.1 - 0.29 11.8 21.9 0.81 10.3 4.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3371) E7 PF00527.13 CDI85952.1 - 0.33 11.1 12.1 1.5 9.0 1.3 2.5 2 0 0 2 2 2 0 E7 protein, Early protein PAXIP1_C PF15364.1 CDI85952.1 - 0.35 10.7 14.3 0.29 11.0 3.5 2.2 2 0 0 2 2 2 0 PAXIP1-associated-protein-1 C term PTIP binding protein FAM60A PF15396.1 CDI85952.1 - 0.35 10.5 11.6 0.32 10.7 2.6 2.1 2 0 0 2 2 2 0 Protein Family FAM60A DUF2215 PF10225.4 CDI85952.1 - 0.39 10.1 10.0 0.49 9.7 1.4 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2215) eIF_4EBP PF05456.6 CDI85952.1 - 0.58 9.8 13.4 0.96 9.1 1.6 2.5 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) SKI PF01202.17 CDI85952.1 - 0.79 9.5 9.9 0.17 11.7 1.1 2.2 2 0 0 2 2 2 0 Shikimate kinase DUF3484 PF11983.3 CDI85952.1 - 0.88 10.4 18.0 2.8 8.8 3.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3484) Mgr1 PF08602.5 CDI85952.1 - 1 8.3 9.5 0.39 9.6 0.2 2.1 2 0 0 2 2 2 0 Mgr1-like, i-AAA protease complex subunit DUF3449 PF11931.3 CDI85952.1 - 1.2 8.6 11.4 5.5 6.4 4.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3449) SPX PF03105.14 CDI85952.1 - 1.3 8.7 12.8 1.3 8.7 2.2 2.1 2 0 0 2 2 2 0 SPX domain NST1 PF13945.1 CDI85952.1 - 2 8.4 24.6 4.7 7.2 9.1 2.2 2 0 0 2 2 2 0 Salt tolerance down-regulator Spt5_N PF11942.3 CDI85952.1 - 2.1 9.0 12.6 0.41 11.2 1.4 2.5 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal EphA2_TM PF14575.1 CDI85952.1 - 2.1 8.7 10.7 11 6.4 0.5 2.5 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain UPF0560 PF10577.4 CDI85952.1 - 2.4 6.3 22.3 0.42 8.8 6.3 2.1 2 0 0 2 2 2 0 Uncharacterised protein family UPF0560 EIIBC-GUT_N PF03612.9 CDI85952.1 - 3 7.4 12.3 3.9 7.0 3.4 2.4 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus DUF3801 PF12687.2 CDI85952.1 - 3.2 7.2 17.7 2.2 7.7 4.7 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3801) Plasmodium_Vir PF05795.6 CDI85952.1 - 4.3 6.4 6.6 3.9 6.5 1.6 2.0 2 0 0 2 2 2 0 Plasmodium vivax Vir protein Rpp20 PF12328.3 CDI85952.1 - 4.8 6.8 12.7 12 5.5 0.2 2.5 2 0 0 2 2 2 0 Rpp20 subunit of nuclear RNase MRP and P TAS2R PF05296.8 CDI85952.1 - 7 5.4 5.9 0.32 9.8 0.3 1.5 2 0 0 2 2 2 0 Mammalian taste receptor protein (TAS2R) PLRV_ORF5 PF01690.12 CDI85952.1 - 7.5 5.5 17.3 10 5.1 12.0 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein DUF3474 PF11960.3 CDI85952.1 - 8 6.4 13.7 6.1 6.8 2.6 2.7 1 1 1 3 3 3 0 Domain of unknown function (DUF3474) MRF_C2 PF13888.1 CDI85952.1 - 8.6 6.1 10.6 1.6 8.5 1.3 2.2 2 0 0 2 2 2 0 Myelin gene regulatory factor C-terminal domain 2 SR-25 PF10500.4 CDI85953.1 - 0.011 15.1 3.7 0.011 15.2 2.6 1.0 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF4457 PF14652.1 CDI85953.1 - 0.016 14.2 2.3 0.018 14.0 1.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4457) DUF1266 PF06889.6 CDI85953.1 - 0.025 14.3 5.2 0.027 14.2 3.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1266) PEX11 PF05648.9 CDI85953.1 - 0.069 12.4 7.0 0.077 12.2 4.8 1.0 1 0 0 1 1 1 0 Peroxisomal biogenesis factor 11 (PEX11) PRP3 PF08572.5 CDI85953.1 - 0.13 11.6 11.5 0.14 11.4 8.0 1.0 1 0 0 1 1 1 0 pre-mRNA processing factor 3 (PRP3) FAM176 PF14851.1 CDI85953.1 - 0.16 11.6 3.1 0.14 11.8 2.2 1.1 1 0 0 1 1 1 0 FAM176 family GBP_C PF02841.9 CDI85953.1 - 0.19 10.8 15.9 0.2 10.7 11.0 1.0 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain FimP PF09766.4 CDI85953.1 - 0.3 10.1 18.5 0.33 9.9 12.8 1.1 1 0 0 1 1 1 0 Fms-interacting protein PEP-utilisers_N PF05524.8 CDI85953.1 - 0.31 10.8 7.6 0.38 10.5 5.2 1.2 1 0 0 1 1 1 0 PEP-utilising enzyme, N-terminal OmpH PF03938.9 CDI85953.1 - 0.34 10.8 27.0 0.4 10.6 18.7 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) FlaG PF03646.10 CDI85953.1 - 0.38 10.9 19.7 0.48 10.5 13.6 1.1 1 0 0 1 1 1 0 FlaG protein Spt20 PF12090.3 CDI85953.1 - 0.39 10.0 10.8 0.42 9.9 7.5 1.2 1 0 0 1 1 1 0 Spt20 family FYDLN_acid PF09538.5 CDI85953.1 - 0.39 11.3 3.2 0.47 11.0 2.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) DUF4407 PF14362.1 CDI85953.1 - 0.48 9.3 17.7 0.57 9.0 12.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF2722 PF10846.3 CDI85953.1 - 0.54 9.2 16.2 0.71 8.8 11.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) eIF-3_zeta PF05091.7 CDI85953.1 - 0.61 8.6 11.6 0.61 8.6 8.0 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Glyco_transf_15 PF01793.11 CDI85953.1 - 0.69 8.8 6.8 0.72 8.7 4.7 1.1 1 0 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase GvpL_GvpF PF06386.6 CDI85953.1 - 0.69 9.4 11.2 0.66 9.5 7.8 1.1 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF DUF3306 PF11748.3 CDI85953.1 - 0.76 10.4 9.0 0.94 10.1 6.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3306) Cellulose_synt PF03552.9 CDI85953.1 - 0.85 7.8 4.3 0.84 7.8 3.0 1.0 1 0 0 1 1 1 0 Cellulose synthase Prp18 PF02840.10 CDI85953.1 - 0.95 9.2 9.6 1 9.1 6.7 1.1 1 0 0 1 1 1 0 Prp18 domain EIIBC-GUT_N PF03612.9 CDI85953.1 - 0.96 9.0 7.1 0.96 9.0 5.0 1.1 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Pex14_N PF04695.8 CDI85953.1 - 1 9.4 14.9 1.1 9.3 10.3 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region GspL_C PF12693.2 CDI85953.1 - 1 9.1 27.6 1.1 8.9 19.1 1.1 1 0 0 1 1 1 0 GspL periplasmic domain DUF1800 PF08811.6 CDI85953.1 - 1 8.2 14.1 0.99 8.2 9.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1800) FAM60A PF15396.1 CDI85953.1 - 1.1 9.0 5.0 1 9.0 3.5 1.1 1 0 0 1 1 1 0 Protein Family FAM60A Folate_carrier PF01770.13 CDI85953.1 - 1.1 7.7 6.2 1.1 7.7 4.3 1.0 1 0 0 1 1 1 0 Reduced folate carrier Spore_coat_CotO PF14153.1 CDI85953.1 - 1.1 8.6 14.3 1.1 8.6 9.9 1.1 1 0 0 1 1 1 0 Spore coat protein CotO Gti1_Pac2 PF09729.4 CDI85953.1 - 1.1 9.1 5.4 1.1 9.0 3.8 1.1 1 0 0 1 1 1 0 Gti1/Pac2 family AIF_C PF14721.1 CDI85953.1 - 1.2 9.4 6.8 1.3 9.2 4.7 1.1 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Glyco_transf_6 PF03414.8 CDI85953.1 - 1.3 7.3 6.7 1.3 7.3 4.6 1.0 1 0 0 1 1 1 0 Glycosyltransferase family 6 Endonuc_Holl PF10107.4 CDI85953.1 - 1.4 8.6 10.6 1.4 8.6 7.4 1.1 1 0 0 1 1 1 0 Endonuclease related to archaeal Holliday junction resolvase Bud13 PF09736.4 CDI85953.1 - 1.4 9.1 14.5 1.5 9.0 10.0 1.1 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex DUF853 PF05872.7 CDI85953.1 - 1.4 7.1 7.6 1.4 7.1 5.3 1.0 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) DDRGK PF09756.4 CDI85953.1 - 1.5 8.2 16.1 1.8 7.9 11.2 1.1 1 0 0 1 1 1 0 DDRGK domain DUF4175 PF13779.1 CDI85953.1 - 1.5 6.4 34.6 1.8 6.2 24.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) DUF3154 PF11351.3 CDI85953.1 - 1.7 8.4 7.3 2.1 8.1 5.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3154) DUF342 PF03961.8 CDI85953.1 - 1.8 6.9 9.4 1.7 6.9 6.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) TrbI PF03743.9 CDI85953.1 - 1.8 7.9 7.0 1.9 7.9 4.8 1.0 1 0 0 1 1 1 0 Bacterial conjugation TrbI-like protein DUF3347 PF11827.3 CDI85953.1 - 2.1 8.3 11.2 2.3 8.2 7.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3347) Kei1 PF08552.6 CDI85953.1 - 2.1 7.9 5.7 2.1 7.9 3.9 1.1 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 YfhO PF09586.5 CDI85953.1 - 2.4 6.0 6.6 2.2 6.1 4.5 1.0 1 0 0 1 1 1 0 Bacterial membrane protein YfhO ATAD4 PF15321.1 CDI85953.1 - 2.5 9.1 9.5 3 8.9 6.6 1.2 1 0 0 1 1 1 0 ATPase family AAA domain containing 4 Ctr PF04145.10 CDI85953.1 - 2.7 8.0 6.2 2.9 7.9 4.3 1.1 1 0 0 1 1 1 0 Ctr copper transporter family Mnd1 PF03962.10 CDI85953.1 - 2.8 7.5 17.8 3.1 7.4 12.4 1.1 1 0 0 1 1 1 0 Mnd1 family DUF702 PF05142.7 CDI85953.1 - 2.8 8.0 9.0 3.1 7.9 6.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF702) Peptidase_S15 PF02129.13 CDI85953.1 - 3.1 7.1 9.3 3.3 7.0 6.5 1.1 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) ATP-synt_E PF05680.7 CDI85953.1 - 3.4 7.6 12.3 4.9 7.1 8.5 1.3 1 0 0 1 1 1 0 ATP synthase E chain Bul1_N PF04425.7 CDI85953.1 - 3.5 6.0 10.0 3.7 5.9 6.9 1.0 1 0 0 1 1 1 0 Bul1 N terminus Peptidase_S49_N PF08496.5 CDI85953.1 - 3.7 7.3 9.2 4.2 7.1 6.4 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal eIF3_subunit PF08597.5 CDI85953.1 - 3.9 6.9 13.5 4.4 6.7 9.3 1.0 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit RR_TM4-6 PF06459.7 CDI85953.1 - 4 7.2 11.8 4.6 7.0 8.2 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Spc7_N PF15402.1 CDI85953.1 - 4.1 5.2 12.5 4.4 5.2 8.7 1.0 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 YlqD PF11068.3 CDI85953.1 - 4.2 7.4 26.7 5.1 7.1 18.5 1.1 1 0 0 1 1 1 0 YlqD protein Exonuc_VII_L PF02601.10 CDI85953.1 - 4.3 6.4 12.6 4.1 6.4 8.7 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit SpoVR PF04293.8 CDI85953.1 - 4.3 5.5 11.1 4.3 5.5 7.7 1.0 1 0 0 1 1 1 0 SpoVR like protein DUF3043 PF11241.3 CDI85953.1 - 4.4 6.8 7.1 5.2 6.6 4.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) CRF1 PF10380.4 CDI85953.1 - 4.5 7.6 7.7 5.8 7.2 5.3 1.3 1 0 0 1 1 1 0 Transcription factor CRF1 Ycf1 PF05758.7 CDI85953.1 - 4.6 4.8 11.2 4.2 4.9 7.7 1.0 1 0 0 1 1 1 0 Ycf1 AAA_11 PF13086.1 CDI85953.1 - 4.8 6.6 12.5 4.9 6.6 8.6 1.0 1 0 0 1 1 1 0 AAA domain FliP PF00813.15 CDI85953.1 - 4.8 6.8 5.7 4.7 6.8 4.0 1.0 1 0 0 1 1 1 0 FliP family Neur_chan_memb PF02932.11 CDI85953.1 - 4.8 6.9 5.2 4.9 6.9 3.6 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region BBS2_C PF14782.1 CDI85953.1 - 4.9 5.6 13.0 5 5.5 9.0 1.1 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, C-terminal PAT1 PF09770.4 CDI85953.1 - 5 5.2 27.2 5.2 5.1 18.9 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Prog_receptor PF02161.10 CDI85953.1 - 5.2 5.7 9.0 5.9 5.5 6.3 1.0 1 0 0 1 1 1 0 Progesterone receptor CDK5_activator PF03261.10 CDI85953.1 - 6 6.1 12.0 6.1 6.0 8.3 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein Pex16 PF08610.5 CDI85953.1 - 6.2 5.7 9.9 6.5 5.6 6.9 1.1 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) FHIPEP PF00771.15 CDI85953.1 - 6.3 4.9 8.6 6.2 5.0 6.0 1.0 1 0 0 1 1 1 0 FHIPEP family DUF775 PF05603.7 CDI85953.1 - 6.8 6.1 14.4 8.3 5.8 10.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF775) Band_3_cyto PF07565.8 CDI85953.1 - 7 6.0 13.6 7.8 5.9 9.4 1.0 1 0 0 1 1 1 0 Band 3 cytoplasmic domain DUF912 PF06024.7 CDI85953.1 - 7.2 6.7 7.1 8.7 6.4 4.9 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Paramyxo_ncap PF00973.14 CDI85953.1 - 7.3 5.1 7.7 7.4 5.1 5.3 1.0 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein DUF4557 PF15101.1 CDI85953.1 - 7.5 6.3 20.6 7.8 6.2 14.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) 5_nucleotid PF05761.9 CDI85953.1 - 7.6 4.9 9.9 7.9 4.8 6.9 1.0 1 0 0 1 1 1 0 5' nucleotidase family Peptidase_C58 PF03543.9 CDI85953.1 - 8.1 5.8 17.6 9.3 5.6 12.2 1.0 1 0 0 1 1 1 0 Yersinia/Haemophilus virulence surface antigen DUF1764 PF08576.5 CDI85953.1 - 8.5 7.2 12.5 9.8 7.0 8.7 1.1 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) DUF4230 PF14014.1 CDI85953.1 - 8.6 6.2 13.8 9.9 6.0 9.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4230) DHHW PF14286.1 CDI85953.1 - 8.9 5.5 7.5 8.6 5.5 5.2 1.0 1 0 0 1 1 1 0 DHHW protein Folliculin PF11704.3 CDI85953.1 - 9.5 5.7 12.4 11 5.5 8.6 1.1 1 0 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport DDHD PF02862.12 CDI85953.1 - 9.6 5.9 14.9 11 5.7 10.3 1.0 1 0 0 1 1 1 0 DDHD domain CDC45 PF02724.9 CDI85954.1 - 8.1 4.3 36.1 10 4.0 25.0 1.1 1 0 0 1 1 1 0 CDC45-like protein NPR3 PF03666.8 CDI85955.1 - 0.0041 15.7 15.2 0.0059 15.1 10.5 1.2 1 0 0 1 1 1 1 Nitrogen Permease regulator of amino acid transport activity 3 DUF2215 PF10225.4 CDI85955.1 - 0.11 11.8 8.1 0.14 11.5 5.6 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) FLO_LFY PF01698.11 CDI85955.1 - 0.11 11.2 28.0 0.15 10.8 19.4 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein Med15 PF09606.5 CDI85955.1 - 0.15 10.2 70.5 0.18 9.9 48.9 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal SOBP PF15279.1 CDI85955.1 - 0.18 12.1 19.7 0.22 11.8 13.6 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein AAA_23 PF13476.1 CDI85955.1 - 0.3 11.3 19.7 0.38 11.0 13.7 1.3 1 0 0 1 1 1 0 AAA domain SARG PF15385.1 CDI85955.1 - 0.44 9.8 27.5 0.5 9.6 19.0 1.0 1 0 0 1 1 1 0 Specifically androgen-regulated gene protein PAT1 PF09770.4 CDI85955.1 - 0.54 8.4 53.3 0.64 8.1 36.9 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF2828 PF11443.3 CDI85955.1 - 0.55 8.3 15.2 0.68 8.0 10.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) CDK5_activator PF03261.10 CDI85955.1 - 0.56 9.4 20.1 0.73 9.1 13.9 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein Caldesmon PF02029.10 CDI85955.1 - 0.62 8.4 22.2 0.76 8.1 15.4 1.1 1 0 0 1 1 1 0 Caldesmon SID-1_RNA_chan PF13965.1 CDI85955.1 - 0.69 8.0 8.5 0.73 7.9 5.9 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 TFIIA PF03153.8 CDI85955.1 - 0.82 9.5 50.1 1 9.1 34.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit MRP-S31 PF15433.1 CDI85955.1 - 1 8.7 28.0 1.4 8.3 19.4 1.2 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 Utp14 PF04615.8 CDI85955.1 - 1.3 7.1 30.7 1.6 6.8 21.3 1.0 1 0 0 1 1 1 0 Utp14 protein PBP1_TM PF14812.1 CDI85955.1 - 1.4 9.3 12.2 0.21 11.8 4.6 2.1 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Cellulose_synt PF03552.9 CDI85955.1 - 1.5 7.0 7.4 1.7 6.8 5.1 1.3 1 0 0 1 1 1 0 Cellulose synthase DUF4045 PF13254.1 CDI85955.1 - 1.8 7.7 24.5 2.3 7.4 17.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) SPX PF03105.14 CDI85955.1 - 1.9 8.1 18.2 2.7 7.6 12.6 1.3 1 0 0 1 1 1 0 SPX domain GAGA_bind PF06217.7 CDI85955.1 - 2 8.2 24.0 2.5 7.9 16.6 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family MASE1 PF05231.9 CDI85955.1 - 2.8 6.8 8.8 0.059 12.3 1.4 1.7 1 1 0 1 1 1 0 MASE1 Peptidase_S64 PF08192.6 CDI85955.1 - 3.6 5.8 22.0 4.3 5.5 15.3 1.0 1 0 0 1 1 1 0 Peptidase family S64 CDC27 PF09507.5 CDI85955.1 - 3.9 6.5 32.4 4.7 6.3 22.5 1.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 DUF572 PF04502.8 CDI85955.1 - 4 6.5 25.5 5.1 6.2 17.6 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Pilt PF15453.1 CDI85955.1 - 4.2 6.9 27.8 5.3 6.6 19.3 1.1 1 0 0 1 1 1 0 Protein incorporated later into Tight Junctions Draxin PF15550.1 CDI85955.1 - 6.1 6.3 25.2 8.7 5.9 17.5 1.2 1 0 0 1 1 1 0 Draxin PPP4R2 PF09184.6 CDI85955.1 - 7.2 6.0 16.2 9 5.7 11.2 1.2 1 0 0 1 1 1 0 PPP4R2 DUF1675 PF07897.6 CDI85955.1 - 7.8 6.2 20.6 11 5.8 14.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) SAPS PF04499.10 CDI85955.1 - 7.9 4.9 21.1 12 4.3 14.6 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Zip PF02535.17 CDI85955.1 - 8.1 5.3 15.6 18 4.1 10.8 1.6 1 1 1 2 2 2 0 ZIP Zinc transporter Nha1_C PF08619.5 CDI85955.1 - 9.2 5.4 28.1 12 5.0 19.5 1.1 1 0 0 1 1 1 0 Alkali metal cation/H+ antiporter Nha1 C terminus LMBR1 PF04791.11 CDI85956.1 - 0.15 10.6 0.0 0.15 10.6 0.0 7.0 4 2 3 7 7 7 0 LMBR1-like membrane protein CDV3 PF15359.1 CDI85958.1 - 0.0066 16.5 4.0 0.0066 16.5 2.8 2.1 2 0 0 2 2 2 1 Carnitine deficiency-associated protein 3 Med15 PF09606.5 CDI85958.1 - 0.029 12.6 56.0 0.036 12.2 38.8 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF342 PF03961.8 CDI85958.1 - 0.19 10.1 3.9 0.19 10.0 2.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) PAT1 PF09770.4 CDI85958.1 - 0.27 9.4 37.2 0.29 9.3 25.8 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Mucin PF01456.12 CDI85958.1 - 0.55 9.9 36.2 1.6 8.5 9.0 2.1 2 0 0 2 2 2 0 Mucin-like glycoprotein GAGA_bind PF06217.7 CDI85958.1 - 1.8 8.4 16.5 2.1 8.2 11.5 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family Macoilin PF09726.4 CDI85958.1 - 2.1 6.5 28.9 2.4 6.3 20.0 1.0 1 0 0 1 1 1 0 Transmembrane protein YfhO PF09586.5 CDI85958.1 - 3.6 5.5 11.7 3.7 5.4 8.1 1.1 1 0 0 1 1 1 0 Bacterial membrane protein YfhO DUF2347 PF09804.4 CDI85958.1 - 5.5 6.1 11.0 8.5 5.5 7.6 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2347) SR-25 PF10500.4 CDI85959.1 - 2.5 7.5 69.9 0.032 13.6 6.1 3.2 2 1 1 3 3 3 0 Nuclear RNA-splicing-associated protein SAGA-Tad1 PF12767.2 CDI85959.1 - 6.6 6.3 44.8 1.1 8.8 5.3 2.5 2 1 0 2 2 2 0 Transcriptional regulator of RNA polII, SAGA, subunit CHZ PF09649.5 CDI85960.1 - 7.4e-05 21.8 1.8 7.4e-05 21.8 1.2 3.8 4 2 0 4 4 2 1 Histone chaperone domain CHZ Cwf_Cwc_15 PF04889.7 CDI85960.1 - 0.003 17.3 33.5 0.0044 16.7 23.2 1.4 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein PPP4R2 PF09184.6 CDI85960.1 - 0.097 12.1 29.0 0.11 11.9 20.1 1.2 1 0 0 1 1 1 0 PPP4R2 SR-25 PF10500.4 CDI85960.1 - 0.14 11.5 47.4 0.11 11.9 16.4 2.1 1 1 1 2 2 2 0 Nuclear RNA-splicing-associated protein GRAS PF03514.9 CDI85960.1 - 0.19 10.3 3.2 0.26 9.9 2.2 1.1 1 0 0 1 1 1 0 GRAS domain family DUF3446 PF11928.3 CDI85960.1 - 0.38 10.9 20.2 0.59 10.3 4.9 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3446) Shadoo PF14999.1 CDI85960.1 - 0.62 9.9 13.5 0.26 11.1 7.9 1.5 1 1 1 2 2 2 0 Shadow of prion protein, neuroprotective POP1 PF06978.6 CDI85960.1 - 0.7 9.5 6.4 0.79 9.3 4.4 1.2 1 0 0 1 1 1 0 Ribonucleases P/MRP protein subunit POP1 Daxx PF03344.10 CDI85960.1 - 1.3 7.4 32.2 1.7 7.0 22.3 1.3 1 0 0 1 1 1 0 Daxx Family SPX PF03105.14 CDI85960.1 - 2 8.1 19.5 2.4 7.8 13.5 1.3 1 0 0 1 1 1 0 SPX domain MSP1_C PF07462.6 CDI85960.1 - 2.5 6.3 13.9 2.5 6.3 9.6 1.1 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus ORC6 PF05460.8 CDI85960.1 - 2.8 6.9 19.7 3.1 6.8 13.7 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) BUD22 PF09073.5 CDI85960.1 - 5.8 5.8 39.3 7.8 5.4 27.3 1.3 1 0 0 1 1 1 0 BUD22 CytochromB561_N PF09786.4 CDI85960.1 - 9.3 4.5 13.1 9.6 4.5 9.1 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal TPR_1 PF00515.23 CDI85961.1 - 1.1e-08 34.2 0.0 2.9e-08 32.9 0.0 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_11 PF13414.1 CDI85961.1 - 1.4e-07 31.0 0.0 3.8e-07 29.6 0.0 1.8 1 0 0 1 1 1 1 TPR repeat TPR_2 PF07719.12 CDI85961.1 - 5.5e-06 25.8 0.2 4.5e-05 23.0 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 CDI85961.1 - 6.1e-05 22.5 0.0 0.00017 21.0 0.0 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_17 PF13431.1 CDI85961.1 - 0.0003 20.7 0.1 0.23 11.7 0.0 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 CDI85961.1 - 0.0003 21.1 0.0 0.003 18.0 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat GFO_IDH_MocA PF01408.17 CDI85961.1 - 0.0035 17.8 0.0 0.011 16.2 0.0 1.8 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold TPR_12 PF13424.1 CDI85961.1 - 0.0051 16.7 0.0 0.016 15.1 0.0 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_7 PF13176.1 CDI85961.1 - 0.069 12.9 0.6 1.7 8.6 0.0 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 CDI85961.1 - 0.13 12.1 0.0 0.29 11.0 0.0 1.5 1 0 0 1 1 1 0 Fis1 C-terminal tetratricopeptide repeat SR-25 PF10500.4 CDI85965.1 - 9.5 5.6 29.3 0.061 12.7 12.9 2.4 1 1 0 2 2 2 0 Nuclear RNA-splicing-associated protein MDMPI_N PF11716.3 CDI85967.1 - 3.4 8.0 54.4 1.4 9.3 15.8 2.4 2 0 0 2 2 2 0 Mycothiol maleylpyruvate isomerase N-terminal domain NTP_transf_3 PF12804.2 CDI85968.1 - 0.55 10.2 10.8 0.69 9.9 7.5 1.2 1 0 0 1 1 1 0 MobA-like NTP transferase domain MCPVI PF02993.9 CDI85968.1 - 2.7 8.0 8.8 3.3 7.8 6.1 1.1 1 0 0 1 1 1 0 Minor capsid protein VI DUF1777 PF08648.7 CDI85969.1 - 0.00038 20.2 55.7 0.00052 19.7 38.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1777) MIP-T3 PF10243.4 CDI85969.1 - 1.7 6.9 48.2 2.1 6.6 33.4 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DUF755 PF05501.6 CDI85972.1 - 6.4e-05 23.0 27.8 6.4e-05 23.0 19.2 5.9 2 1 2 4 4 4 1 Domain of unknown function (DUF755) TSA PF03249.8 CDI85972.1 - 8.3 4.8 13.5 17 3.7 9.3 1.5 1 0 0 1 1 1 0 Type specific antigen Reticulon PF02453.12 CDI85973.1 - 0.022 14.3 0.2 0.022 14.3 0.2 2.9 3 1 1 4 4 4 0 Reticulon gag-asp_proteas PF13975.1 CDI85974.1 - 1.4e-10 40.8 0.1 2.6e-10 39.9 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVT_1 PF00078.22 CDI85974.1 - 3.2e-10 39.7 0.0 5.8e-10 38.8 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.1 CDI85974.1 - 2.8e-08 34.1 0.0 5.2e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.15 CDI85974.1 - 8e-06 25.6 0.0 5.5e-05 23.0 0.0 2.1 1 1 0 1 1 1 1 Retroviral aspartyl protease RVP_2 PF08284.6 CDI85974.1 - 1.5e-05 24.9 0.0 2.7e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease Chromo PF00385.19 CDI85976.1 - 2.3e-09 36.7 0.0 5.8e-09 35.4 0.0 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain DUF2303 PF10065.4 CDI85977.1 - 0.014 14.3 0.0 0.026 13.4 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2303) DUF2767 PF10965.3 CDI85978.1 - 0.084 12.7 0.0 8.3 6.3 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2767) Ribosomal_L12 PF00542.14 CDI85979.1 - 4.2e-22 77.9 2.1 4.2e-22 77.9 1.5 1.7 2 0 0 2 2 2 1 Ribosomal protein L7/L12 C-terminal domain FAD_binding_3 PF01494.14 CDI85980.1 - 2.4e-41 141.9 0.7 2.9e-18 66.0 0.0 4.5 2 2 1 4 4 4 3 FAD binding domain NAD_binding_8 PF13450.1 CDI85980.1 - 0.0023 17.9 0.1 0.0067 16.4 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 CDI85980.1 - 0.02 13.9 0.0 0.033 13.2 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Pyr_redox_2 PF07992.9 CDI85980.1 - 0.029 14.2 0.0 0.056 13.3 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase SUV3_C PF12513.3 CDI85981.1 - 5.3e-10 38.5 0.7 1.2e-09 37.3 0.0 1.9 2 0 0 2 2 2 1 Mitochondrial degradasome RNA helicase subunit C terminal Helicase_C PF00271.26 CDI85981.1 - 2.6e-05 23.9 0.0 0.00011 21.9 0.0 2.1 1 1 0 1 1 1 1 Helicase conserved C-terminal domain BTB_2 PF02214.17 CDI85982.1 - 2.2e-14 53.4 0.1 5e-14 52.2 0.0 1.6 2 0 0 2 2 2 1 BTB/POZ domain Nol1_Nop2_Fmu PF01189.12 CDI85984.1 - 3.6e-14 52.8 0.0 2.1e-07 30.5 0.0 2.3 2 0 0 2 2 2 2 NOL1/NOP2/sun family Methyltransf_26 PF13659.1 CDI85984.1 - 0.011 15.7 0.0 0.018 15.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain FtsJ PF01728.14 CDI85984.1 - 0.1 12.6 0.1 0.32 10.9 0.0 2.0 2 1 0 2 2 2 0 FtsJ-like methyltransferase ATAD4 PF15321.1 CDI85985.1 - 0.081 13.9 0.3 0.081 13.9 0.2 2.6 2 1 0 2 2 2 0 ATPase family AAA domain containing 4 2-Hacid_dh PF00389.25 CDI85985.1 - 2.1 7.8 4.1 0.88 9.0 0.6 2.0 1 1 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain DOG1 PF14144.1 CDI85985.1 - 2.4 8.2 7.4 12 5.9 0.8 3.4 2 1 1 3 3 3 0 Seed dormancy control ALMT PF11744.3 CDI85985.1 - 5.6 5.5 7.8 7.9 5.0 5.4 1.3 1 1 0 1 1 1 0 Aluminium activated malate transporter DUF3287 PF11690.3 CDI85985.1 - 9.9 6.2 10.2 1.1 9.4 2.8 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3287) CDK2AP PF09806.4 CDI85986.1 - 0.00063 20.0 5.6 0.001 19.3 3.9 1.3 1 1 0 1 1 1 1 Cyclin-dependent kinase 2-associated protein SR-25 PF10500.4 CDI85986.1 - 0.00091 18.7 7.6 0.0013 18.3 5.2 1.2 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein DUF4636 PF15468.1 CDI85986.1 - 0.054 12.9 3.7 0.076 12.4 2.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4636) SDP_N PF12278.3 CDI85986.1 - 0.059 12.9 2.2 0.089 12.4 1.6 1.3 1 0 0 1 1 1 0 Sex determination protein N terminal DUF1635 PF07795.6 CDI85986.1 - 0.12 11.6 9.4 0.21 10.9 6.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) DUF4657 PF15552.1 CDI85986.1 - 0.17 11.1 9.3 0.28 10.4 6.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4657) Chorion_2 PF03964.10 CDI85986.1 - 0.18 12.3 5.8 5.1 7.6 0.7 2.2 2 0 0 2 2 2 0 Chorion family 2 DUF3573 PF12097.3 CDI85986.1 - 0.26 9.8 4.7 0.33 9.5 3.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) ATG16 PF08614.6 CDI85986.1 - 0.3 10.8 9.9 0.025 14.3 3.9 1.4 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) Glyco_hydro_10 PF00331.15 CDI85986.1 - 0.31 10.0 4.1 0.34 9.8 2.7 1.2 1 1 0 1 1 1 0 Glycosyl hydrolase family 10 DUF972 PF06156.8 CDI85986.1 - 0.57 10.5 6.2 0.84 10.0 4.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF972) DUF3513 PF12026.3 CDI85986.1 - 0.82 9.1 8.6 1.3 8.5 6.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3513) Pap_E4 PF02711.9 CDI85986.1 - 0.89 10.4 5.2 0.92 10.3 2.7 1.7 2 0 0 2 2 2 0 E4 protein YABBY PF04690.8 CDI85986.1 - 1.4 9.1 6.3 2.4 8.3 4.4 1.4 1 0 0 1 1 1 0 YABBY protein RAP1 PF07218.6 CDI85986.1 - 2.1 6.3 6.0 2.8 5.9 4.1 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Allexi_40kDa PF05549.6 CDI85986.1 - 4 6.6 7.7 5.6 6.1 5.4 1.1 1 0 0 1 1 1 0 Allexivirus 40kDa protein DUF3801 PF12687.2 CDI85988.1 - 0.68 9.4 30.5 0.82 9.2 21.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3801) DUF2663 PF10864.3 CDI85989.1 - 1.9 8.7 9.0 0.11 12.7 1.5 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2663) Arv1 PF04161.8 CDI85989.1 - 2.6 7.9 12.7 4.6 7.0 8.8 1.4 1 0 0 1 1 1 0 Arv1-like family O-antigen_lig PF13425.1 CDI85989.1 - 2.6 8.0 14.3 8.2 6.4 0.1 2.5 2 0 0 2 2 2 0 O-antigen ligase like membrane protein DEC-1_N PF04625.8 CDI85990.1 - 0.65 8.6 9.7 0.89 8.1 6.7 1.2 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Pur_DNA_glyco PF02245.11 CDI85992.1 - 1.5 7.9 6.5 1.6 7.8 4.1 1.3 1 1 0 1 1 1 0 Methylpurine-DNA glycosylase (MPG) FAM60A PF15396.1 CDI85992.1 - 5 6.8 18.6 7 6.3 12.9 1.2 1 0 0 1 1 1 0 Protein Family FAM60A RNA_pol_Rpb1_5 PF04998.12 CDI85992.1 - 5.4 6.1 11.6 6.8 5.8 8.0 1.3 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 Glyco_hydro_9 PF00759.14 CDI85992.1 - 7.9 5.2 12.0 9.7 4.9 8.3 1.0 1 0 0 1 1 1 0 Glycosyl hydrolase family 9 PAT1 PF09770.4 CDI85992.1 - 8.5 4.4 59.0 10 4.2 40.9 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SR-25 PF10500.4 CDI85993.1 - 0.0049 16.3 1.6 0.0049 16.3 1.1 1.6 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein FliX PF10768.4 CDI85993.1 - 0.0091 16.2 2.0 0.016 15.4 1.4 1.4 1 0 0 1 1 1 1 Class II flagellar assembly regulator TMEM51 PF15345.1 CDI85993.1 - 0.11 12.2 5.1 0.044 13.4 1.4 1.7 2 0 0 2 2 2 0 Transmembrane protein 51 ExbD PF02472.11 CDI85993.1 - 0.67 9.9 4.3 0.16 11.9 0.7 1.7 2 0 0 2 2 2 0 Biopolymer transport protein ExbD/TolR SAPS PF04499.10 CDI85995.1 - 0.0041 15.8 13.9 13 4.2 0.0 2.8 2 2 0 2 2 2 1 SIT4 phosphatase-associated protein Suf PF05843.9 CDI85995.1 - 0.015 15.0 53.1 1.7 8.2 17.6 4.3 4 0 0 4 4 4 0 Suppressor of forked protein (Suf) DUF3449 PF11931.3 CDI85995.1 - 0.032 13.7 28.8 0.58 9.6 0.0 4.0 4 0 0 4 4 4 0 Domain of unknown function (DUF3449) Spore_YhcN_YlaJ PF09580.5 CDI85995.1 - 6.3 6.8 31.3 26 4.8 0.0 4.1 4 0 0 4 4 4 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) DUF755 PF05501.6 CDI85996.1 - 0.69 9.9 49.8 0.33 11.0 22.8 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF755) PLRV_ORF5 PF01690.12 CDI85996.1 - 1.3 8.1 20.0 1.2 8.2 7.5 2.1 2 0 0 2 2 2 0 Potato leaf roll virus readthrough protein Spt20 PF12090.3 CDI85996.1 - 1.3 8.3 18.9 1.7 7.9 0.4 2.5 2 0 0 2 2 2 0 Spt20 family SLD3 PF08639.5 CDI85996.1 - 3.6 6.1 29.3 0.61 8.6 11.8 2.1 2 0 0 2 2 2 0 DNA replication regulator SLD3 DDRGK PF09756.4 CDI85996.1 - 5.9 6.2 18.3 2 7.8 7.1 2.2 2 0 0 2 2 2 0 DDRGK domain Spc7 PF08317.6 CDI85997.1 - 0.0061 15.2 14.2 0.0061 15.2 9.8 2.2 1 1 1 2 2 2 1 Spc7 kinetochore protein Fib_alpha PF08702.5 CDI85997.1 - 0.01 15.9 2.4 0.01 15.9 1.7 2.6 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family Reo_sigmaC PF04582.7 CDI85997.1 - 0.031 13.4 6.6 0.99 8.5 0.2 2.2 1 1 1 2 2 2 0 Reovirus sigma C capsid protein Filament PF00038.16 CDI85997.1 - 0.11 11.9 27.0 0.085 12.3 10.6 2.1 1 1 1 2 2 2 0 Intermediate filament protein AAA_13 PF13166.1 CDI85997.1 - 0.16 10.3 26.9 0.31 9.4 18.7 1.4 1 1 0 1 1 1 0 AAA domain ATG16 PF08614.6 CDI85997.1 - 0.18 11.6 33.0 0.03 14.1 8.2 2.7 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) T2SF PF00482.18 CDI85997.1 - 0.41 10.5 6.8 6.7 6.6 0.1 2.2 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein F NPV_P10 PF05531.7 CDI85997.1 - 0.47 10.7 11.9 1.6 9.0 1.5 3.0 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein RHD PF00554.17 CDI85997.1 - 0.48 10.1 6.0 0.83 9.3 3.8 1.5 1 1 0 1 1 1 0 Rel homology domain (RHD) V_ATPase_I PF01496.14 CDI85997.1 - 0.78 7.5 18.3 1.2 6.8 12.7 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family GAS PF13851.1 CDI85997.1 - 0.83 8.8 33.7 0.25 10.4 16.5 2.4 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Cauli_DNA-bind PF03310.8 CDI85997.1 - 1.7 8.4 9.4 0.38 10.5 1.7 2.5 2 0 0 2 2 2 0 Caulimovirus DNA-binding protein CENP-Q PF13094.1 CDI85997.1 - 2.1 8.3 29.3 0.39 10.7 12.3 2.4 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit IncA PF04156.9 CDI85997.1 - 2.3 7.7 34.1 0.043 13.4 17.6 2.0 1 1 1 2 2 2 0 IncA protein CDC37_N PF03234.9 CDI85997.1 - 2.5 8.3 26.4 0.68 10.2 10.7 2.2 1 1 1 2 2 2 0 Cdc37 N terminal kinase binding TMF_TATA_bd PF12325.3 CDI85997.1 - 2.7 7.7 29.6 4.2 7.1 2.8 3.2 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding TPR_MLP1_2 PF07926.7 CDI85997.1 - 3.5 7.3 34.8 2 8.1 4.8 2.8 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein ADIP PF11559.3 CDI85997.1 - 3.8 7.4 35.1 18 5.2 10.9 3.1 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding COG2 PF06148.6 CDI85997.1 - 5 7.0 18.8 0.71 9.7 4.8 3.0 2 1 1 3 3 2 0 COG (conserved oligomeric Golgi) complex component, COG2 GrpE PF01025.14 CDI85997.1 - 5.2 6.5 24.9 0.38 10.2 2.4 3.0 1 1 1 2 2 2 0 GrpE DUF641 PF04859.7 CDI85997.1 - 5.8 6.6 23.3 0.63 9.8 1.8 3.3 1 1 2 3 3 3 0 Plant protein of unknown function (DUF641) DinB PF05163.7 CDI85997.1 - 6.5 6.4 10.4 1.4 8.6 1.9 2.7 1 1 2 3 3 3 0 DinB family DUF812 PF05667.6 CDI85997.1 - 7.3 4.9 30.6 0.0089 14.5 7.6 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF812) ING PF12998.2 CDI85997.1 - 8.2 6.7 24.3 0.8 10.0 7.5 2.3 1 1 1 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding Vps51 PF08700.6 CDI85997.1 - 8.7 6.2 16.8 2.1 8.2 0.1 4.0 2 2 2 4 4 4 0 Vps51/Vps67 ADH_N PF08240.7 CDI85998.1 - 0.00029 20.5 0.1 0.00054 19.6 0.0 1.5 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain Med15 PF09606.5 CDI85998.1 - 0.0061 14.8 13.6 0.0056 14.9 9.4 1.1 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal DUF3154 PF11351.3 CDI85998.1 - 0.021 14.5 0.1 0.026 14.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3154) DUF3371 PF11851.3 CDI85998.1 - 0.047 14.3 4.6 0.059 14.0 3.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3371) Spt20 PF12090.3 CDI85998.1 - 0.1 11.9 2.4 0.11 11.8 1.7 1.1 1 0 0 1 1 1 0 Spt20 family RAB3GAP2_N PF14655.1 CDI85998.1 - 0.17 10.8 4.2 0.19 10.6 2.9 1.0 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus PAT1 PF09770.4 CDI85998.1 - 0.28 9.3 10.0 0.29 9.3 6.9 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Suf PF05843.9 CDI85998.1 - 0.3 10.7 3.5 0.3 10.7 2.4 1.0 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Activator_LAG-3 PF11498.3 CDI85998.1 - 0.36 9.5 19.2 0.4 9.3 13.3 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Med3 PF11593.3 CDI85998.1 - 0.4 9.8 11.1 0.48 9.6 7.7 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DivIC PF04977.10 CDI85998.1 - 1.6 8.2 8.5 2 7.9 5.9 1.2 1 0 0 1 1 1 0 Septum formation initiator Peptidase_C97 PF05903.9 CDI85999.1 - 1.2e-08 34.8 0.0 2.5e-08 33.8 0.0 1.4 1 0 0 1 1 1 1 PPPDE putative peptidase domain Peptidase_S49_N PF08496.5 CDI86000.1 - 1.2 8.9 21.7 0.82 9.4 3.8 3.8 4 0 0 4 4 4 0 Peptidase family S49 N-terminal DUF4642 PF15484.1 CDI86001.1 - 0.081 12.9 1.2 0.099 12.6 0.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4642) EPL1 PF10513.4 CDI86001.1 - 0.25 11.5 7.9 0.28 11.4 5.5 1.1 1 0 0 1 1 1 0 Enhancer of polycomb-like Pex14_N PF04695.8 CDI86001.1 - 0.27 11.2 15.6 0.37 10.8 10.8 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region MAT1 PF06391.8 CDI86001.1 - 0.45 10.0 9.9 0.57 9.7 6.9 1.0 1 0 0 1 1 1 0 CDK-activating kinase assembly factor MAT1 SR-25 PF10500.4 CDI86001.1 - 0.53 9.7 11.4 0.72 9.2 7.9 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Suf PF05843.9 CDI86001.1 - 0.7 9.5 16.4 0.88 9.2 11.4 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) RR_TM4-6 PF06459.7 CDI86001.1 - 0.92 9.3 5.3 0.92 9.3 3.7 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 LIM_bind PF01803.11 CDI86001.1 - 1.5 7.9 11.8 1.6 7.8 8.2 1.0 1 0 0 1 1 1 0 LIM-domain binding protein DHHW PF14286.1 CDI86001.1 - 1.9 7.7 5.6 1.9 7.7 3.9 1.0 1 0 0 1 1 1 0 DHHW protein DUF4557 PF15101.1 CDI86001.1 - 2 8.1 13.9 2.2 8.0 9.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) Nucleo_P87 PF07267.6 CDI86001.1 - 2.3 6.8 7.9 2.5 6.6 5.5 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Sox_N PF12444.3 CDI86001.1 - 2.3 9.3 10.3 2.9 9.0 7.1 1.1 1 0 0 1 1 1 0 Sox developmental protein N terminal DUF2360 PF10152.4 CDI86001.1 - 2.6 8.3 9.2 3.5 7.9 6.4 1.2 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) SARG PF15385.1 CDI86001.1 - 2.8 7.2 13.4 3.2 7.0 9.3 1.0 1 0 0 1 1 1 0 Specifically androgen-regulated gene protein Endonuc_Holl PF10107.4 CDI86001.1 - 2.8 7.6 8.0 3 7.5 5.6 1.1 1 0 0 1 1 1 0 Endonuclease related to archaeal Holliday junction resolvase DUF533 PF04391.7 CDI86001.1 - 3.2 7.0 16.1 4 6.7 11.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF533) Gag_spuma PF03276.9 CDI86001.1 - 3.3 5.9 17.5 3.7 5.7 12.1 1.0 1 0 0 1 1 1 0 Spumavirus gag protein OmpH PF03938.9 CDI86001.1 - 3.4 7.5 23.2 3.6 7.5 16.1 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF2058 PF09831.4 CDI86001.1 - 3.4 7.5 17.1 3.7 7.4 11.9 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2058) PAT1 PF09770.4 CDI86001.1 - 3.4 5.7 23.4 3.6 5.6 16.2 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF702 PF05142.7 CDI86001.1 - 3.8 7.6 10.2 4.3 7.4 7.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF702) TFIIA PF03153.8 CDI86001.1 - 3.9 7.2 20.3 4.4 7.0 14.1 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Peptidase_S15 PF02129.13 CDI86001.1 - 4 6.7 9.3 4.8 6.5 6.4 1.1 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Band_3_cyto PF07565.8 CDI86001.1 - 5.4 6.4 10.4 6.6 6.1 7.2 1.0 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Spore_coat_CotO PF14153.1 CDI86001.1 - 5.7 6.3 15.6 6.7 6.1 10.8 1.1 1 0 0 1 1 1 0 Spore coat protein CotO DUF4175 PF13779.1 CDI86001.1 - 6 4.4 25.3 6.6 4.2 17.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) RIC3 PF15361.1 CDI86001.1 - 6.6 6.9 9.8 7.5 6.7 6.8 1.2 1 0 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 EIIBC-GUT_N PF03612.9 CDI86001.1 - 8.4 5.9 6.5 9.5 5.7 4.5 1.1 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus DUF1764 PF08576.5 CDI86001.1 - 8.5 7.2 9.1 11 6.8 6.3 1.3 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) RED_N PF07808.8 CDI86001.1 - 9.6 5.3 11.1 11 5.1 7.7 1.2 1 0 0 1 1 1 0 RED-like protein N-terminal region tRNA-synt_1b PF00579.20 CDI86002.1 - 4.2e-14 52.3 16.3 5.8e-07 28.9 7.2 3.9 3 1 0 3 3 3 2 tRNA synthetases class I (W and Y) Suf PF05843.9 CDI86002.1 - 6e-05 22.9 3.8 6e-05 22.9 2.6 5.9 5 1 1 6 6 6 1 Suppressor of forked protein (Suf) FimP PF09766.4 CDI86002.1 - 0.0033 16.5 7.3 0.0033 16.5 5.1 6.2 5 1 1 6 6 6 3 Fms-interacting protein IncA PF04156.9 CDI86002.1 - 0.0048 16.5 10.4 0.0048 16.5 7.2 7.5 8 1 1 9 9 9 1 IncA protein S4 PF01479.20 CDI86002.1 - 0.012 15.0 0.0 0.029 13.7 0.0 1.7 1 0 0 1 1 1 0 S4 domain Spt20 PF12090.3 CDI86002.1 - 0.012 14.9 0.9 0.012 14.9 0.6 7.2 6 1 0 6 6 6 0 Spt20 family Mem_trans PF03547.13 CDI86002.1 - 3.4 5.8 0.0 3.4 5.8 0.0 4.4 3 2 2 5 5 5 0 Membrane transport protein NUDIX PF00293.23 CDI86003.1 - 1.1e-12 47.7 0.0 2e-12 46.9 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain DDHD PF02862.12 CDI86003.1 - 0.00092 19.0 0.3 0.0012 18.6 0.2 1.2 1 0 0 1 1 1 1 DDHD domain Spt20 PF12090.3 CDI86003.1 - 0.0011 18.3 6.2 0.33 10.2 0.1 2.2 2 0 0 2 2 2 2 Spt20 family Neur_chan_memb PF02932.11 CDI86003.1 - 0.0028 17.5 0.5 0.005 16.7 0.4 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region DUF2722 PF10846.3 CDI86003.1 - 0.015 14.3 11.5 0.023 13.7 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) Androgen_recep PF02166.11 CDI86003.1 - 0.015 14.1 15.8 0.038 12.8 3.1 2.1 2 0 0 2 2 2 0 Androgen receptor Apc1 PF12859.2 CDI86003.1 - 0.02 15.1 7.6 0.031 14.4 1.4 2.4 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 1 DUF912 PF06024.7 CDI86003.1 - 0.02 14.9 4.0 1.2 9.2 0.1 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) FHIPEP PF00771.15 CDI86003.1 - 0.037 12.3 4.7 0.79 7.9 0.5 2.0 2 0 0 2 2 2 0 FHIPEP family RNA_pol_Rpb1_5 PF04998.12 CDI86003.1 - 0.047 12.9 0.1 0.062 12.5 0.1 1.1 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 DUF775 PF05603.7 CDI86003.1 - 0.048 13.1 9.3 0.6 9.5 0.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF775) zf-DHHC PF01529.15 CDI86003.1 - 0.056 12.8 1.2 3.7 6.9 0.3 2.2 2 0 0 2 2 2 0 DHHC palmitoyltransferase Med15 PF09606.5 CDI86003.1 - 0.066 11.4 40.5 0.0043 15.3 8.3 2.0 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal Serinc PF03348.10 CDI86003.1 - 0.079 11.6 3.9 1.4 7.5 0.6 2.1 2 0 0 2 2 2 0 Serine incorporator (Serinc) Hep_59 PF07052.6 CDI86003.1 - 0.087 13.1 9.8 1.1 9.6 0.2 2.2 2 0 0 2 2 2 0 Hepatocellular carcinoma-associated antigen 59 Suf PF05843.9 CDI86003.1 - 0.095 12.4 17.6 0.56 9.8 3.1 2.1 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) OATP PF03137.15 CDI86003.1 - 0.097 10.7 2.5 2 6.3 0.2 2.0 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Semialdhyde_dh PF01118.19 CDI86003.1 - 0.11 12.7 0.1 0.33 11.2 0.0 1.8 2 0 0 2 2 1 0 Semialdehyde dehydrogenase, NAD binding domain Gti1_Pac2 PF09729.4 CDI86003.1 - 0.18 11.7 2.6 8.8 6.1 0.2 2.1 2 0 0 2 2 2 0 Gti1/Pac2 family GBP_C PF02841.9 CDI86003.1 - 0.24 10.5 19.8 0.23 10.6 5.3 2.1 2 0 0 2 2 2 0 Guanylate-binding protein, C-terminal domain TFIIA PF03153.8 CDI86003.1 - 0.31 10.9 19.0 0.49 10.2 3.6 2.0 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Glyco_transf_7N PF13733.1 CDI86003.1 - 0.35 10.2 5.6 0.053 12.8 0.9 1.8 2 0 0 2 2 2 0 N-terminal region of glycosyl transferase group 7 RbsD_FucU PF05025.8 CDI86003.1 - 0.35 11.1 3.4 1.8 8.8 0.1 2.3 2 0 0 2 2 2 0 RbsD / FucU transport protein family PCYCGC PF13798.1 CDI86003.1 - 0.39 10.3 7.1 0.22 11.1 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function with PCYCGC motif AIF_C PF14721.1 CDI86003.1 - 0.4 10.9 5.3 5.6 7.2 0.4 2.2 2 0 0 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Folliculin PF11704.3 CDI86003.1 - 0.41 10.2 9.2 0.57 9.7 0.7 2.1 2 0 0 2 2 2 0 Vesicle coat protein involved in Golgi to plasma membrane transport FimP PF09766.4 CDI86003.1 - 0.47 9.4 22.4 1.5 7.8 4.6 2.1 2 0 0 2 2 2 0 Fms-interacting protein BRF1 PF07741.8 CDI86003.1 - 0.56 10.4 12.1 0.52 10.5 0.2 2.3 2 0 0 2 2 2 0 Brf1-like TBP-binding domain EIIBC-GUT_N PF03612.9 CDI86003.1 - 0.67 9.5 6.1 3.2 7.3 0.3 2.1 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus CagX PF03524.10 CDI86003.1 - 0.67 9.1 9.0 2.4 7.3 0.4 2.1 2 0 0 2 2 2 0 Conjugal transfer protein Helicase_RecD PF05127.9 CDI86003.1 - 0.7 9.5 5.0 3.9 7.0 0.1 2.1 2 0 0 2 2 2 0 Helicase DUF3299 PF11736.3 CDI86003.1 - 0.71 9.7 8.2 0.91 9.4 0.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3299) zf-ZPR1 PF03367.8 CDI86003.1 - 0.75 8.9 5.5 3.1 6.9 0.5 2.2 2 0 0 2 2 2 0 ZPR1 zinc-finger domain IncA PF04156.9 CDI86003.1 - 0.76 9.3 23.4 0.39 10.2 3.1 2.1 2 0 0 2 2 2 0 IncA protein DUF3371 PF11851.3 CDI86003.1 - 0.84 10.3 19.5 0.35 11.5 1.9 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3371) Dynamin_N PF00350.18 CDI86003.1 - 0.9 9.3 4.3 12 5.6 0.3 2.1 2 0 0 2 2 2 0 Dynamin family DUF4063 PF13272.1 CDI86003.1 - 0.97 9.2 4.6 1.4 8.7 0.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4063) DUF4483 PF14825.1 CDI86003.1 - 0.97 9.0 14.9 1.2 8.7 2.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4483) PigN PF04987.9 CDI86003.1 - 0.99 7.9 5.1 4.5 5.7 0.1 2.1 2 0 0 2 2 2 0 Phosphatidylinositolglycan class N (PIG-N) DUF1418 PF07214.7 CDI86003.1 - 1.1 8.9 3.3 2.5 7.7 0.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1418) Ctr PF04145.10 CDI86003.1 - 1.2 9.1 5.9 4.6 7.2 0.4 2.1 2 0 0 2 2 2 0 Ctr copper transporter family DUF607 PF04678.8 CDI86003.1 - 1.8 8.4 6.5 12 5.7 1.6 2.1 2 0 0 2 2 2 0 Protein of unknown function, DUF607 Pex14_N PF04695.8 CDI86003.1 - 1.8 8.6 16.4 0.58 10.2 1.4 2.2 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region ATAD4 PF15321.1 CDI86003.1 - 2 9.4 9.6 11 7.0 1.3 2.2 2 0 0 2 2 2 0 ATPase family AAA domain containing 4 Transglut_core3 PF13471.1 CDI86003.1 - 2.3 8.0 7.1 4.5 7.0 1.3 2.3 2 0 0 2 2 2 0 Transglutaminase-like superfamily PRP3 PF08572.5 CDI86003.1 - 2.3 7.5 17.2 1.7 7.9 4.2 2.2 2 0 0 2 2 2 0 pre-mRNA processing factor 3 (PRP3) Hom_end_hint PF05203.11 CDI86003.1 - 2.4 7.8 6.8 1.4 8.6 0.6 2.1 2 0 0 2 2 2 0 Hom_end-associated Hint RAB3GAP2_N PF14655.1 CDI86003.1 - 2.4 7.0 14.9 0.58 9.1 1.9 2.1 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Mis12 PF05859.7 CDI86003.1 - 3 7.6 12.2 1 9.1 1.3 2.2 2 0 0 2 2 2 0 Mis12 protein DUF2126 PF09899.4 CDI86003.1 - 3.1 5.7 7.7 1.4 6.8 0.9 2.0 2 0 0 2 2 2 0 Putative amidoligase enzyme (DUF2126) Conotoxin PF02950.12 CDI86003.1 - 3.1 8.6 12.7 7.3 7.4 2.7 2.3 2 0 0 2 2 2 0 Conotoxin 60KD_IMP PF02096.15 CDI86003.1 - 3.5 7.2 11.2 5.8 6.5 0.1 2.1 2 0 0 2 2 2 0 60Kd inner membrane protein GOLD_2 PF13897.1 CDI86003.1 - 3.5 7.8 4.5 12 6.1 0.8 2.1 2 0 0 2 2 2 0 Golgi-dynamics membrane-trafficking DUF1840 PF08895.6 CDI86003.1 - 3.9 7.5 13.7 2.2 8.3 2.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1840) Shisa PF13908.1 CDI86003.1 - 4.1 7.5 11.1 2.1 8.5 0.4 2.2 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator Agouti PF05039.7 CDI86003.1 - 4.1 7.8 13.5 1.5 9.2 3.3 2.2 2 0 0 2 2 2 0 Agouti protein SeqA PF03925.8 CDI86003.1 - 5 6.7 10.7 6.8 6.3 0.7 2.1 2 0 0 2 2 2 0 SeqA protein PH_4 PF15404.1 CDI86003.1 - 5 6.6 10.4 15 5.0 1.7 2.8 3 0 0 3 3 3 0 Pleckstrin homology domain MRF_C2 PF13888.1 CDI86003.1 - 5.2 6.8 7.6 11 5.7 0.6 2.3 2 0 0 2 2 2 0 Myelin gene regulatory factor C-terminal domain 2 Pex16 PF08610.5 CDI86003.1 - 5.4 5.9 10.1 2.8 6.8 1.0 2.1 2 0 0 2 2 2 0 Peroxisomal membrane protein (Pex16) eIF3g PF12353.3 CDI86003.1 - 5.6 6.8 13.6 1.8 8.4 2.5 2.1 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit G DUF4628 PF15429.1 CDI86003.1 - 6.1 6.1 10.5 7 5.9 1.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4628) Glyco_transf_15 PF01793.11 CDI86003.1 - 7.6 5.3 10.8 0.9 8.4 1.3 2.0 2 0 0 2 2 2 0 Glycolipid 2-alpha-mannosyltransferase CIAPIN1 PF05093.8 CDI86004.1 - 0.00082 19.4 4.9 0.00097 19.1 3.4 1.1 1 0 0 1 1 1 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis SR-25 PF10500.4 CDI86004.1 - 0.0061 16.0 3.4 0.0074 15.7 2.4 1.0 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Cellulose_synt PF03552.9 CDI86004.1 - 0.053 11.8 0.3 0.051 11.8 0.2 1.0 1 0 0 1 1 1 0 Cellulose synthase RNA_pol_Rpc4 PF05132.9 CDI86004.1 - 0.11 12.4 2.3 0.13 12.2 1.6 1.1 1 0 0 1 1 1 0 RNA polymerase III RPC4 Spt20 PF12090.3 CDI86004.1 - 0.13 11.6 4.8 0.13 11.5 3.3 1.1 1 0 0 1 1 1 0 Spt20 family FCP1_C PF09309.5 CDI86004.1 - 0.16 11.2 6.7 0.19 11.0 4.6 1.1 1 0 0 1 1 1 0 FCP1, C-terminal Pex14_N PF04695.8 CDI86004.1 - 0.16 12.0 5.9 0.18 11.8 4.1 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region ERF PF04404.7 CDI86004.1 - 0.19 11.2 7.6 0.2 11.1 5.3 1.1 1 0 0 1 1 1 0 ERF superfamily Ycf1 PF05758.7 CDI86004.1 - 0.25 9.0 2.1 0.24 9.0 1.5 1.0 1 0 0 1 1 1 0 Ycf1 OATP PF03137.15 CDI86004.1 - 0.25 9.3 3.9 0.27 9.2 2.7 1.0 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family AIF_C PF14721.1 CDI86004.1 - 0.25 11.5 1.8 0.27 11.4 1.2 1.1 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Serinc PF03348.10 CDI86004.1 - 0.34 9.5 2.8 0.33 9.5 2.0 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) DUF4407 PF14362.1 CDI86004.1 - 0.41 9.5 2.6 0.43 9.4 1.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Med3 PF11593.3 CDI86004.1 - 0.5 9.5 11.1 0.48 9.5 7.7 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal TCP PF03634.8 CDI86004.1 - 0.54 10.6 8.5 0.62 10.4 5.9 1.0 1 0 0 1 1 1 0 TCP family transcription factor DUF4366 PF14283.1 CDI86004.1 - 0.57 9.5 5.8 0.67 9.3 4.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) Activator_LAG-3 PF11498.3 CDI86004.1 - 0.57 8.8 16.9 0.61 8.7 11.7 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 FimP PF09766.4 CDI86004.1 - 0.72 8.8 12.4 0.8 8.7 8.6 1.0 1 0 0 1 1 1 0 Fms-interacting protein Sox_N PF12444.3 CDI86004.1 - 0.86 10.7 6.3 1.1 10.4 4.4 1.1 1 0 0 1 1 1 0 Sox developmental protein N terminal Suf PF05843.9 CDI86004.1 - 1.1 8.9 6.4 1.2 8.8 4.4 1.0 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) RAB3GAP2_N PF14655.1 CDI86004.1 - 1.4 7.8 4.9 1.4 7.8 3.4 1.1 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus DUF4175 PF13779.1 CDI86004.1 - 1.5 6.4 15.7 1.6 6.3 10.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) TAF4 PF05236.9 CDI86004.1 - 1.6 7.9 8.5 1.8 7.7 5.9 1.1 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family UPF0560 PF10577.4 CDI86004.1 - 2.1 6.4 7.0 2.2 6.4 4.8 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 CDC45 PF02724.9 CDI86004.1 - 2.9 5.8 7.6 3.4 5.6 5.3 1.0 1 0 0 1 1 1 0 CDC45-like protein Gag_spuma PF03276.9 CDI86004.1 - 4.8 5.3 10.0 5.2 5.2 7.0 1.0 1 0 0 1 1 1 0 Spumavirus gag protein SprA-related PF12118.3 CDI86004.1 - 5.3 6.2 17.1 6.3 6.0 11.8 1.1 1 0 0 1 1 1 0 SprA-related family Solute_trans_a PF03619.11 CDI86005.1 - 1.3e-39 136.1 8.4 1.8e-30 106.1 0.2 3.2 2 1 1 3 3 3 3 Organic solute transporter Ostalpha Inhibitor_I71 PF12628.2 CDI86005.1 - 0.081 12.5 0.3 0.081 12.5 0.2 1.5 2 0 0 2 2 2 0 Falstatin, cysteine peptidase inhibitor RAP1 PF07218.6 CDI86006.1 - 0.083 10.9 11.5 0.11 10.5 8.0 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) AAA_23 PF13476.1 CDI86006.1 - 0.11 12.7 10.8 0.29 11.4 2.1 2.2 2 0 0 2 2 2 0 AAA domain DUF1183 PF06682.7 CDI86006.1 - 0.35 10.4 18.7 0.31 10.5 8.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1183) Hist_deacetyl PF00850.14 CDI86006.1 - 0.88 8.7 6.6 7.1 5.8 3.3 2.1 1 1 1 2 2 2 0 Histone deacetylase domain SART-1 PF03343.8 CDI86006.1 - 1.2 7.3 15.6 2 6.6 10.8 1.4 1 1 0 1 1 1 0 SART-1 family ETRAMP PF09716.5 CDI86006.1 - 1.3 9.0 17.9 0.3 11.0 0.4 3.7 2 1 1 3 3 3 0 Malarial early transcribed membrane protein (ETRAMP) Hid1 PF12722.2 CDI86006.1 - 3.5 5.1 15.0 5.2 4.6 10.4 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein APC_CDC26 PF10471.4 CDI86006.1 - 4.9 7.9 46.8 1.9 9.2 2.4 3.7 2 1 1 3 3 3 0 Anaphase-promoting complex APC subunit 1 MRP-S31 PF15433.1 CDI86006.1 - 7.9 5.8 27.3 0.043 13.2 10.2 2.4 2 1 0 2 2 2 0 Mitochondrial 28S ribosomal protein S31 MS_channel PF00924.13 CDI86007.1 - 1.1e-11 44.4 1.6 1.6e-11 43.9 1.1 1.2 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_8 PF13833.1 CDI86007.1 - 0.0053 16.3 0.1 0.011 15.3 0.0 1.6 1 0 0 1 1 1 1 EF-hand domain pair EOS1 PF12326.3 CDI86007.1 - 0.017 14.7 4.0 0.38 10.3 2.5 2.3 2 0 0 2 2 2 0 N-glycosylation protein MIP-T3 PF10243.4 CDI86008.1 - 0.00028 19.5 87.1 0.00032 19.3 60.4 1.0 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 Utp14 PF04615.8 CDI86008.1 - 3.5 5.6 90.8 4 5.4 62.9 1.1 1 0 0 1 1 1 0 Utp14 protein Daxx PF03344.10 CDI86008.1 - 3.6 5.9 72.5 4.5 5.6 50.3 1.1 1 0 0 1 1 1 0 Daxx Family YajC PF02699.10 CDI86010.1 - 1.2 8.8 4.4 2.6 7.7 3.0 1.5 1 0 0 1 1 1 0 Preprotein translocase subunit CAF-1_p150 PF11600.3 CDI86011.1 - 0.98 8.7 39.2 0.076 12.3 22.3 2.1 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal FUSC PF04632.7 CDI86011.1 - 6.8 4.9 26.3 8.6 4.6 18.2 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF1980 PF09323.5 CDI86012.1 - 0.053 13.2 7.3 0.88 9.2 2.2 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF1980) Spt20 PF12090.3 CDI86012.1 - 1.1 8.5 10.0 0.28 10.5 0.5 2.1 2 0 0 2 2 2 0 Spt20 family DUF677 PF05055.7 CDI86012.1 - 4.7 5.7 9.4 9.7 4.7 6.5 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF677) FimP PF09766.4 CDI86012.1 - 5 6.1 17.6 0.4 9.7 1.8 2.0 2 0 0 2 2 2 0 Fms-interacting protein DUF1675 PF07897.6 CDI86012.1 - 5.5 6.7 7.8 6.6 6.5 5.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) zf-DHHC PF01529.15 CDI86012.1 - 6.4 6.1 6.0 22 4.3 0.0 2.1 2 0 0 2 2 2 0 DHHC palmitoyltransferase IPP-2 PF04979.9 CDI86012.1 - 9.2 6.5 9.8 4.2 7.6 2.6 2.1 2 0 0 2 2 2 0 Protein phosphatase inhibitor 2 (IPP-2) DUF572 PF04502.8 CDI86013.1 - 0.0016 17.7 22.6 0.0016 17.7 15.7 2.9 2 1 1 3 3 3 2 Family of unknown function (DUF572) PH_4 PF15404.1 CDI86014.1 - 0.13 11.7 1.7 0.15 11.6 1.2 1.0 1 0 0 1 1 1 0 Pleckstrin homology domain ATAD4 PF15321.1 CDI86014.1 - 0.17 12.9 4.8 0.2 12.6 3.3 1.1 1 0 0 1 1 1 0 ATPase family AAA domain containing 4 Pex14_N PF04695.8 CDI86014.1 - 0.18 11.8 7.4 0.17 11.9 5.1 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region RR_TM4-6 PF06459.7 CDI86014.1 - 0.44 10.3 4.3 0.51 10.2 3.0 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF4407 PF14362.1 CDI86014.1 - 0.48 9.3 5.1 0.49 9.3 3.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) FCP1_C PF09309.5 CDI86014.1 - 0.48 9.6 8.6 0.53 9.5 6.0 1.0 1 0 0 1 1 1 0 FCP1, C-terminal Med15 PF09606.5 CDI86014.1 - 0.71 7.9 20.5 0.71 7.9 14.2 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal PAT1 PF09770.4 CDI86014.1 - 0.98 7.5 15.6 1 7.5 10.8 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF775 PF05603.7 CDI86014.1 - 1.1 8.6 5.2 1.3 8.5 3.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF775) SSDP PF04503.8 CDI86014.1 - 1.2 8.7 10.5 1.3 8.6 7.3 1.0 1 0 0 1 1 1 0 Single-stranded DNA binding protein, SSDP G0-G1_switch_2 PF15103.1 CDI86014.1 - 1.4 9.2 5.1 1.6 8.9 3.5 1.1 1 0 0 1 1 1 0 G0/G1 switch protein 2 DUF3464 PF11947.3 CDI86014.1 - 1.5 8.2 4.5 1.7 8.1 3.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) DUF3408 PF11888.3 CDI86014.1 - 1.5 8.7 7.2 1.7 8.5 5.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) Spt20 PF12090.3 CDI86014.1 - 1.6 8.0 10.8 1.7 7.9 7.5 1.0 1 0 0 1 1 1 0 Spt20 family FimP PF09766.4 CDI86014.1 - 1.8 7.5 13.0 2 7.4 9.0 1.0 1 0 0 1 1 1 0 Fms-interacting protein PHD_3 PF13922.1 CDI86014.1 - 2.9 8.1 10.2 3.8 7.8 7.1 1.2 1 0 0 1 1 1 0 PHD domain of transcriptional enhancer, Asx Pex16 PF08610.5 CDI86014.1 - 3.4 6.5 6.2 3.5 6.5 4.3 1.0 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) UPF0560 PF10577.4 CDI86014.1 - 3.5 5.7 9.0 3.4 5.7 6.2 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 DUF4557 PF15101.1 CDI86014.1 - 4.1 7.1 10.6 4.7 6.9 7.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) Serinc PF03348.10 CDI86014.1 - 4.4 5.8 4.8 4.8 5.7 3.3 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) RED_N PF07808.8 CDI86014.1 - 5.3 6.1 9.8 6.1 5.9 6.8 1.0 1 0 0 1 1 1 0 RED-like protein N-terminal region DivIC PF04977.10 CDI86014.1 - 5.9 6.4 11.4 7.5 6.1 7.9 1.1 1 0 0 1 1 1 0 Septum formation initiator Gag_spuma PF03276.9 CDI86014.1 - 5.9 5.0 15.2 6.3 4.9 10.6 1.0 1 0 0 1 1 1 0 Spumavirus gag protein ERF PF04404.7 CDI86014.1 - 9.8 5.6 13.6 12 5.4 9.5 1.1 1 0 0 1 1 1 0 ERF superfamily NinG PF05766.7 CDI86015.1 - 0.021 14.6 20.2 0.022 14.4 14.0 1.1 1 0 0 1 1 1 0 Bacteriophage Lambda NinG protein DUF3347 PF11827.3 CDI86015.1 - 0.6 10.0 16.3 0.65 9.9 11.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3347) Dala_Dala_lig_N PF01820.16 CDI86015.1 - 1.2 9.4 8.2 1.6 9.0 5.7 1.3 1 0 0 1 1 1 0 D-ala D-ala ligase N-terminus DUF3457 PF11939.3 CDI86015.1 - 1.4 8.4 9.8 1.7 8.1 6.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3457) DUF3260 PF11658.3 CDI86015.1 - 1.5 6.8 17.2 1.4 6.9 11.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3260) Raftlin PF15250.1 CDI86015.1 - 1.5 7.2 16.2 1.7 7.1 11.3 1.0 1 0 0 1 1 1 0 Raftlin PEX11 PF05648.9 CDI86015.1 - 1.7 7.8 10.1 2 7.6 7.0 1.3 1 0 0 1 1 1 0 Peroxisomal biogenesis factor 11 (PEX11) AIF_C PF14721.1 CDI86015.1 - 1.7 8.8 12.6 1.9 8.7 8.8 1.2 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Auxin_canalis PF05703.6 CDI86015.1 - 2 8.1 8.4 2.2 8.0 5.8 1.1 1 0 0 1 1 1 0 Auxin canalisation FYDLN_acid PF09538.5 CDI86015.1 - 2.3 8.8 7.8 2.6 8.6 5.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) TraV PF09676.5 CDI86015.1 - 3 8.5 13.2 3.5 8.3 9.1 1.2 1 0 0 1 1 1 0 Type IV conjugative transfer system lipoprotein (TraV) CD20 PF04103.10 CDI86015.1 - 3.5 7.5 6.9 4.1 7.3 4.8 1.2 1 0 0 1 1 1 0 CD20-like family GOLD_2 PF13897.1 CDI86015.1 - 3.5 7.8 8.1 3.7 7.7 5.6 1.1 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking PcfK PF14058.1 CDI86015.1 - 3.6 7.7 20.6 5.7 7.0 14.3 1.3 1 0 0 1 1 1 0 PcfK-like protein Pex14_N PF04695.8 CDI86015.1 - 3.6 7.6 23.2 4.3 7.3 16.1 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Serinc PF03348.10 CDI86015.1 - 3.9 6.0 15.9 3.7 6.1 11.0 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) EIIBC-GUT_N PF03612.9 CDI86015.1 - 3.9 7.0 13.3 4.3 6.9 9.2 1.1 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus FAM176 PF14851.1 CDI86015.1 - 4.3 7.0 10.1 4.9 6.8 7.0 1.2 1 0 0 1 1 1 0 FAM176 family K_trans PF02705.11 CDI86015.1 - 4.3 5.5 5.3 4.2 5.6 3.7 1.1 1 0 0 1 1 1 0 K+ potassium transporter DUF1266 PF06889.6 CDI86015.1 - 4.7 6.9 17.2 5.3 6.8 12.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1266) RbsD_FucU PF05025.8 CDI86015.1 - 5.3 7.3 11.0 6.7 7.0 7.6 1.1 1 0 0 1 1 1 0 RbsD / FucU transport protein family PCYCGC PF13798.1 CDI86015.1 - 5.6 6.6 9.0 6.9 6.3 6.2 1.2 1 0 0 1 1 1 0 Protein of unknown function with PCYCGC motif FHIPEP PF00771.15 CDI86015.1 - 6.4 4.9 13.5 5.9 5.0 9.4 1.0 1 0 0 1 1 1 0 FHIPEP family RR_TM4-6 PF06459.7 CDI86015.1 - 6.6 6.5 16.9 7.1 6.4 11.7 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF4512 PF14975.1 CDI86015.1 - 7.2 7.5 8.3 9.2 7.1 5.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4512) SeqA PF03925.8 CDI86015.1 - 7.4 6.2 14.7 7.5 6.2 10.2 1.1 1 0 0 1 1 1 0 SeqA protein Peptidase_U57 PF05582.7 CDI86015.1 - 7.8 5.3 14.4 7.9 5.3 10.0 1.1 1 0 0 1 1 1 0 YabG peptidase U57 Suf PF05843.9 CDI86015.1 - 9 5.9 21.9 11 5.6 15.2 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) TraH_2 PF06871.6 CDI86015.1 - 9.7 5.5 7.3 9.6 5.5 5.1 1.2 1 0 0 1 1 1 0 TraH_2 RNA_capsid PF03035.9 CDI86016.1 - 0.0083 15.9 2.2 0.0096 15.7 1.5 1.1 1 0 0 1 1 1 1 Calicivirus putative RNA polymerase/capsid protein CDK2AP PF09806.4 CDI86016.1 - 0.043 14.0 6.5 0.048 13.8 4.5 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein PPP4R2 PF09184.6 CDI86016.1 - 0.23 10.9 2.2 0.29 10.6 1.5 1.0 1 0 0 1 1 1 0 PPP4R2 SR-25 PF10500.4 CDI86016.1 - 0.41 10.0 7.4 0.47 9.8 5.2 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein CAF-1_p150 PF11600.3 CDI86017.1 - 0.18 11.1 89.1 0.23 10.8 14.9 2.3 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal SprA-related PF12118.3 CDI86019.1 - 0.0025 17.2 20.2 0.0025 17.2 14.0 3.9 3 2 0 3 3 3 1 SprA-related family SPX PF03105.14 CDI86019.1 - 0.71 9.5 0.0 0.71 9.5 0.0 3.1 2 1 1 3 3 3 0 SPX domain PBP1_TM PF14812.1 CDI86019.1 - 2.3 8.5 19.4 4.4 7.6 0.0 3.4 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Na_Ca_ex PF01699.19 CDI86020.1 - 1.4e-38 131.6 31.9 1.5e-22 79.6 9.8 2.3 2 0 0 2 2 2 2 Sodium/calcium exchanger protein DUF872 PF05915.7 CDI86020.1 - 2.6 7.9 4.6 1.2 9.0 0.4 2.4 1 1 1 2 2 2 0 Eukaryotic protein of unknown function (DUF872) RAB3GAP2_N PF14655.1 CDI86021.1 - 1.7 7.5 29.5 0.45 9.4 2.6 2.1 1 1 1 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus LSM PF01423.17 CDI86022.1 - 2e-13 49.6 0.2 2.3e-13 49.4 0.2 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 CDI86022.1 - 0.00013 21.8 0.4 0.00064 19.6 0.3 1.8 1 1 0 1 1 1 1 Ataxin 2 SM domain HemX PF04375.9 CDI86023.1 - 0.12 10.9 37.5 0.14 10.6 26.0 1.1 1 0 0 1 1 1 0 HemX Ycf1 PF05758.7 CDI86023.1 - 0.2 9.3 14.5 0.17 9.5 10.1 1.2 1 0 0 1 1 1 0 Ycf1 Hid1 PF12722.2 CDI86023.1 - 0.89 7.1 14.5 0.8 7.2 10.1 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein AAA_23 PF13476.1 CDI86023.1 - 1 9.6 22.6 1.1 9.5 15.6 1.2 1 0 0 1 1 1 0 AAA domain DUF4483 PF14825.1 CDI86023.1 - 1.4 8.5 23.4 1.1 8.8 14.8 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4483) Med15 PF09606.5 CDI86023.1 - 1.9 6.5 63.7 2.1 6.4 44.1 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal eIF-3_zeta PF05091.7 CDI86023.1 - 2 6.9 19.9 2 6.9 13.8 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) NMDAR2_C PF10565.4 CDI86023.1 - 2.1 6.9 18.1 1.9 7.0 12.6 1.2 1 0 0 1 1 1 0 N-methyl D-aspartate receptor 2B3 C-terminus DUF2215 PF10225.4 CDI86023.1 - 3.9 6.8 9.8 4.6 6.6 6.8 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) GOLD_2 PF13897.1 CDI86023.1 - 4.1 7.6 13.3 0.66 10.2 5.1 2.3 1 1 1 2 2 2 0 Golgi-dynamics membrane-trafficking Folate_carrier PF01770.13 CDI86023.1 - 7 5.0 10.9 11 4.4 7.6 1.3 1 0 0 1 1 1 0 Reduced folate carrier MDM1 PF15501.1 CDI86024.1 - 1 8.2 8.4 1.3 7.8 5.8 1.1 1 0 0 1 1 1 0 Nuclear protein MDM1 DoxX_3 PF13781.1 CDI86024.1 - 2.9 8.2 10.7 0.18 12.1 2.3 2.1 1 1 1 2 2 2 0 DoxX-like family Di19_C PF14571.1 CDI86025.1 - 0.0019 18.4 1.4 0.0019 18.4 1.0 3.2 3 1 0 3 3 3 1 Stress-induced protein Di19, C-terminal PcfK PF14058.1 CDI86025.1 - 0.01 15.9 5.1 0.01 15.9 3.5 3.1 2 1 1 3 3 3 0 PcfK-like protein FimP PF09766.4 CDI86025.1 - 0.16 10.9 29.0 0.056 12.5 6.9 2.2 2 0 0 2 2 2 0 Fms-interacting protein Herpes_BLLF1 PF05109.8 CDI86025.1 - 0.88 7.4 11.3 1.1 7.1 7.8 1.1 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) zf-DHHC PF01529.15 CDI86025.1 - 0.95 8.8 8.3 5.2 6.4 2.1 2.2 2 0 0 2 2 2 0 DHHC palmitoyltransferase AAA_23 PF13476.1 CDI86025.1 - 1.4 9.2 17.2 6.6 7.0 0.1 2.1 2 0 0 2 2 2 0 AAA domain DUF3357 PF11837.3 CDI86025.1 - 2.1 8.2 9.0 5.3 6.9 0.5 3.3 2 1 0 3 3 3 0 Domain of unknown function (DUF3357) DBC1 PF14443.1 CDI86025.1 - 4.8 6.7 12.1 2 7.9 1.6 2.5 2 0 0 2 2 2 0 DBC1 Pex14_N PF04695.8 CDI86026.1 - 0.004 17.2 11.9 0.004 17.2 8.2 1.6 2 0 0 2 2 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region MAM PF00629.18 CDI86026.1 - 0.055 13.2 4.2 0.074 12.8 2.9 1.2 1 0 0 1 1 1 0 MAM domain Vma12 PF11712.3 CDI86026.1 - 0.12 12.1 1.7 0.17 11.6 0.7 1.4 1 1 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase DUF2457 PF10446.4 CDI86026.1 - 0.19 10.4 3.2 0.18 10.4 2.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) PH_4 PF15404.1 CDI86026.1 - 0.32 10.4 2.3 0.46 9.9 1.6 1.2 1 0 0 1 1 1 0 Pleckstrin homology domain Kei1 PF08552.6 CDI86026.1 - 0.79 9.3 3.7 1.1 8.8 2.6 1.5 1 1 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 RED_N PF07808.8 CDI86026.1 - 2.7 7.1 8.9 4.2 6.5 6.2 1.4 1 0 0 1 1 1 0 RED-like protein N-terminal region SOBP PF15279.1 CDI86027.1 - 0.003 18.0 10.9 0.003 18.0 7.5 2.1 2 0 0 2 2 2 1 Sine oculis-binding protein Med19 PF10278.4 CDI86027.1 - 5.2 6.6 7.1 9.6 5.8 4.9 1.4 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 FCP1_C PF09309.5 CDI86029.1 - 0.00054 19.3 5.8 0.00054 19.3 4.0 3.1 3 0 0 3 3 3 1 FCP1, C-terminal Fmp27_WPPW PF10359.4 CDI86029.1 - 0.047 12.0 24.8 0.12 10.7 5.9 2.2 2 0 0 2 2 2 0 RNA pol II promoter Fmp27 protein domain Reprolysin_2 PF13574.1 CDI86029.1 - 0.18 11.8 9.8 1.2 9.2 0.5 2.2 2 0 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like Gti1_Pac2 PF09729.4 CDI86029.1 - 0.29 10.9 21.6 1.2 8.9 4.6 2.3 2 0 0 2 2 2 0 Gti1/Pac2 family RNA_lig_T4_1 PF09511.5 CDI86029.1 - 0.37 10.2 13.1 0.16 11.3 0.4 2.2 2 0 0 2 2 2 0 RNA ligase Late_protein_L2 PF00513.13 CDI86029.1 - 1.2 7.8 15.6 0.19 10.5 3.0 2.1 2 0 0 2 2 2 0 Late Protein L2 FAM60A PF15396.1 CDI86029.1 - 1.5 8.4 24.2 1.5 8.4 4.4 2.2 2 0 0 2 2 2 0 Protein Family FAM60A DUF1943 PF09172.6 CDI86029.1 - 1.9 7.2 23.0 0.074 11.9 0.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1943) Dala_Dala_lig_N PF01820.16 CDI86029.1 - 1.9 8.7 19.9 1.4 9.2 1.9 2.7 3 0 0 3 3 2 0 D-ala D-ala ligase N-terminus SpoVR PF04293.8 CDI86029.1 - 2.1 6.6 29.8 0.77 8.0 5.0 2.2 2 0 0 2 2 2 0 SpoVR like protein GOLD_2 PF13897.1 CDI86029.1 - 2.8 8.1 14.8 2 8.6 0.8 2.4 2 0 0 2 2 2 0 Golgi-dynamics membrane-trafficking Peptidase_S15 PF02129.13 CDI86029.1 - 2.9 7.2 33.3 1.9 7.8 7.7 2.4 2 1 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) Ycf1 PF05758.7 CDI86029.1 - 3.4 5.2 31.0 0.5 8.0 7.4 2.1 2 0 0 2 2 2 0 Ycf1 SDF PF00375.13 CDI86029.1 - 4.5 5.9 11.8 5.4 5.6 1.1 2.2 2 0 0 2 2 2 0 Sodium:dicarboxylate symporter family TraT PF05818.7 CDI86029.1 - 4.9 6.5 32.4 0.029 13.8 5.8 2.6 2 0 0 2 2 2 0 Enterobacterial TraT complement resistance protein Raftlin PF15250.1 CDI86029.1 - 5.5 5.4 25.8 0.3 9.5 3.3 2.2 2 0 0 2 2 2 0 Raftlin Hid1 PF12722.2 CDI86029.1 - 5.8 4.4 33.0 1.4 6.5 9.8 2.1 2 0 0 2 2 2 0 High-temperature-induced dauer-formation protein Tfb4 PF03850.9 CDI86029.1 - 5.9 6.0 27.2 0.12 11.6 5.5 2.2 2 0 0 2 2 2 0 Transcription factor Tfb4 Plasmodium_Vir PF05795.6 CDI86029.1 - 5.9 5.9 13.2 5.8 6.0 2.4 2.2 2 0 0 2 2 2 0 Plasmodium vivax Vir protein DUF506 PF04720.7 CDI86029.1 - 7.3 6.1 19.5 3 7.4 2.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF506) DUF2828 PF11443.3 CDI86029.1 - 7.6 4.6 21.7 0.41 8.8 1.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF2828) Otopetrin PF03189.8 CDI86029.1 - 8.2 5.3 16.0 1.4 7.8 2.3 2.1 2 0 0 2 2 2 0 Otopetrin DUF912 PF06024.7 CDI86029.1 - 9.9 6.2 33.2 0.15 12.1 4.7 3.0 3 1 0 3 3 3 0 Nucleopolyhedrovirus protein of unknown function (DUF912) PID_2 PF14719.1 CDI86030.1 - 0.01 15.4 1.7 0.01 15.4 1.2 3.6 3 0 0 3 3 3 0 Phosphotyrosine interaction domain (PTB/PID) Potyvirid-P3 PF13608.1 CDI86031.1 - 0.21 10.6 3.0 0.27 10.2 2.1 1.2 1 0 0 1 1 1 0 Protein P3 of Potyviral polyprotein APC_CDC26 PF10471.4 CDI86031.1 - 1.3 9.7 8.8 1.9 9.2 6.1 1.5 1 1 0 1 1 1 0 Anaphase-promoting complex APC subunit 1 Med15 PF09606.5 CDI86031.1 - 2.3 6.3 18.6 2.7 6.0 12.9 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF2116 PF09889.4 CDI86031.1 - 3.2 7.6 4.7 5.6 6.8 3.3 1.3 1 0 0 1 1 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) Phostensin_N PF13916.1 CDI86031.1 - 5.1 7.1 8.7 9 6.3 6.0 1.3 1 0 0 1 1 1 0 PP1-regulatory protein, Phostensin N-terminal Nucleocapsid-N PF11030.3 CDI86031.1 - 6.4 6.5 11.7 7.1 6.4 8.1 1.1 1 0 0 1 1 1 0 Nucleocapsid protein N DUF1266 PF06889.6 CDI86031.1 - 9.7 5.9 7.4 12 5.6 5.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1266) Bacteriocin_IIc PF10439.4 CDI86035.1 - 1.8 8.7 6.4 3.7 7.7 4.4 1.4 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide Gly-zipper_YMGG PF13441.1 CDI86035.1 - 1.9 8.0 8.7 4.1 6.9 6.0 1.6 1 0 0 1 1 1 0 YMGG-like Gly-zipper RskA PF10099.4 CDI86036.1 - 0.014 15.1 6.6 0.014 15.1 4.6 3.2 2 1 0 2 2 2 0 Anti-sigma-K factor rskA Tom22 PF04281.8 CDI86036.1 - 0.98 8.9 8.7 0.091 12.2 0.8 2.6 2 0 0 2 2 2 0 Mitochondrial import receptor subunit Tom22 Vert_HS_TF PF06546.6 CDI86036.1 - 3.4 7.0 15.4 0.14 11.5 0.4 2.3 2 0 0 2 2 2 0 Vertebrate heat shock transcription factor FimP PF09766.4 CDI86036.1 - 5.3 6.0 14.5 0.048 12.7 4.0 1.8 2 0 0 2 2 2 0 Fms-interacting protein Zip PF02535.17 CDI86037.1 - 0.0045 16.0 5.4 0.0049 15.9 3.7 1.3 1 0 0 1 1 1 1 ZIP Zinc transporter CDC45 PF02724.9 CDI86037.1 - 0.0049 14.9 15.1 0.0059 14.7 10.5 1.2 1 0 0 1 1 1 1 CDC45-like protein Presenilin PF01080.12 CDI86037.1 - 0.0049 15.7 7.8 0.0055 15.5 5.4 1.1 1 0 0 1 1 1 1 Presenilin MRP-S31 PF15433.1 CDI86037.1 - 0.012 15.0 22.9 0.014 14.8 15.9 1.1 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 TRAP_alpha PF03896.11 CDI86037.1 - 0.028 13.4 2.6 0.032 13.2 1.8 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Serinc PF03348.10 CDI86037.1 - 0.031 12.9 14.3 0.036 12.7 9.9 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) DUF3987 PF13148.1 CDI86037.1 - 0.042 12.4 6.6 0.055 12.0 4.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) HCO3_cotransp PF00955.16 CDI86037.1 - 0.046 12.3 1.6 0.05 12.2 1.1 1.1 1 0 0 1 1 1 0 HCO3- transporter family Plasmodium_Vir PF05795.6 CDI86037.1 - 0.055 12.6 2.5 0.059 12.5 1.7 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Herpes_MCP PF03122.9 CDI86037.1 - 0.11 9.8 10.0 0.11 9.8 6.9 1.0 1 0 0 1 1 1 0 Herpes virus major capsid protein DUF4366 PF14283.1 CDI86037.1 - 0.18 11.1 13.2 0.043 13.2 3.5 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4366) SID-1_RNA_chan PF13965.1 CDI86037.1 - 0.22 9.6 14.2 0.27 9.3 9.9 1.2 1 1 0 1 1 1 0 dsRNA-gated channel SID-1 DUF3449 PF11931.3 CDI86037.1 - 0.33 10.4 21.1 0.02 14.3 10.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3449) Raftlin PF15250.1 CDI86037.1 - 0.34 9.3 18.5 0.4 9.1 12.9 1.1 1 0 0 1 1 1 0 Raftlin Ndc1_Nup PF09531.5 CDI86037.1 - 0.59 8.4 14.0 0.73 8.1 9.7 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Daxx PF03344.10 CDI86037.1 - 0.66 8.3 20.1 0.81 8.1 13.9 1.2 1 0 0 1 1 1 0 Daxx Family RBP_receptor PF14752.1 CDI86037.1 - 0.83 7.9 6.7 0.91 7.7 4.6 1.1 1 0 0 1 1 1 0 Retinol binding protein receptor DUF2347 PF09804.4 CDI86037.1 - 1.6 7.9 18.8 1.9 7.6 13.0 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2347) DUF2370 PF10176.4 CDI86037.1 - 2 7.7 16.0 3.4 6.9 11.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2370) DUF2828 PF11443.3 CDI86037.1 - 2 6.5 13.3 2.3 6.3 9.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) NAD_binding_5 PF07994.7 CDI86037.1 - 2.2 7.6 5.3 2.5 7.5 3.6 1.1 1 0 0 1 1 1 0 Myo-inositol-1-phosphate synthase LMBR1 PF04791.11 CDI86037.1 - 2.4 6.6 9.6 2.5 6.5 6.7 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein FAM91_C PF14648.1 CDI86037.1 - 2.4 6.9 10.2 2.4 6.8 7.1 1.1 1 0 0 1 1 1 0 FAM91 C-terminus DUF4220 PF13968.1 CDI86037.1 - 2.5 7.1 8.2 2.8 6.9 5.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4220) Cellulose_synt PF03552.9 CDI86037.1 - 2.7 6.1 6.9 2.7 6.1 4.8 1.1 1 0 0 1 1 1 0 Cellulose synthase ARF7EP_C PF14949.1 CDI86037.1 - 3 8.3 22.9 1.4e+02 2.9 15.8 2.3 1 1 0 1 1 1 0 ARF7 effector protein C-terminus Utp14 PF04615.8 CDI86037.1 - 3.3 5.7 27.3 4 5.4 18.9 1.1 1 0 0 1 1 1 0 Utp14 protein VID27 PF08553.5 CDI86037.1 - 3.5 5.7 15.1 3.6 5.6 10.5 1.1 1 0 0 1 1 1 0 VID27 cytoplasmic protein DUF3604 PF12228.3 CDI86037.1 - 3.8 5.5 16.8 4.7 5.2 11.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3604) PIH1 PF08190.7 CDI86037.1 - 3.9 6.8 26.1 5 6.4 18.1 1.2 1 0 0 1 1 1 0 pre-RNA processing PIH1/Nop17 YqfQ PF14181.1 CDI86037.1 - 4 7.4 26.9 0.27 11.2 14.0 1.9 2 0 0 2 2 2 0 YqfQ-like protein SpaB_C PF14028.1 CDI86037.1 - 5.1 6.5 7.6 6.2 6.2 5.3 1.1 1 0 0 1 1 1 0 SpaB C-terminal domain Isy1 PF06246.7 CDI86037.1 - 6.1 6.1 27.9 7.3 5.9 19.4 1.1 1 0 0 1 1 1 0 Isy1-like splicing family Hid1 PF12722.2 CDI86037.1 - 6.4 4.3 25.1 7.4 4.1 17.4 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein RNA_pol_Rpb1_5 PF04998.12 CDI86037.1 - 7 5.8 12.9 8.4 5.5 8.9 1.1 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 PLRV_ORF5 PF01690.12 CDI86037.1 - 9.5 5.2 19.9 11 5.0 13.8 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein ABC2_membrane PF01061.19 CDI86038.1 - 3e-12 46.1 10.8 4.4e-12 45.6 7.5 1.2 1 0 0 1 1 1 1 ABC-2 type transporter ABC2_membrane_3 PF12698.2 CDI86038.1 - 5.4e-07 28.9 9.1 7.5e-07 28.4 6.3 1.1 1 0 0 1 1 1 1 ABC-2 family transporter protein ABC_tran PF00005.22 CDI86038.1 - 3.4e-06 27.3 0.0 5.7e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_2 PF12679.2 CDI86038.1 - 0.00069 18.5 5.0 0.0011 17.9 3.4 1.2 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_21 PF13304.1 CDI86038.1 - 0.0053 16.7 0.0 0.008 16.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain WW PF00397.21 CDI86039.1 - 2e-08 33.9 0.6 4.3e-08 32.8 0.4 1.5 1 0 0 1 1 1 1 WW domain DegT_DnrJ_EryC1 PF01041.12 CDI86040.1 - 1.3e-15 57.2 0.0 7.8e-15 54.7 0.0 2.0 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Dynein_heavy PF03028.10 CDI86041.1 - 5.2e-141 471.0 0.0 2e-139 465.7 0.0 2.3 2 0 0 2 2 2 1 Dynein heavy chain and region D6 of dynein motor DHC_N2 PF08393.8 CDI86041.1 - 3.6e-102 341.9 0.0 3.6e-102 341.9 0.0 2.9 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 2 AAA_6 PF12774.2 CDI86041.1 - 7.5e-93 310.2 0.0 1.4e-92 309.4 0.0 1.4 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region D1 MT PF12777.2 CDI86041.1 - 3.8e-42 144.2 6.5 3.8e-42 144.2 4.5 1.8 2 0 0 2 2 1 1 Microtubule-binding stalk of dynein motor AAA_5 PF07728.9 CDI86041.1 - 2.1e-18 66.3 0.0 7e-06 25.8 0.0 5.6 3 2 0 3 3 3 3 AAA domain (dynein-related subfamily) AAA_7 PF12775.2 CDI86041.1 - 3.1e-13 49.4 0.0 1.6e-12 47.1 0.0 2.0 2 0 0 2 2 2 1 P-loop containing dynein motor region D3 AAA_16 PF13191.1 CDI86041.1 - 1e-11 45.1 0.1 0.014 15.4 0.0 5.0 3 0 0 3 3 3 3 AAA ATPase domain AAA_9 PF12781.2 CDI86041.1 - 1.5e-11 43.5 0.0 3.6e-11 42.3 0.0 1.6 1 0 0 1 1 1 1 ATP-binding dynein motor region D5 AAA PF00004.24 CDI86041.1 - 5.6e-09 36.2 0.2 0.0037 17.4 0.0 4.5 4 0 0 4 4 3 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 CDI86041.1 - 1.2e-08 35.2 0.1 0.11 12.5 0.0 4.6 4 0 0 4 4 3 2 AAA domain AAA_18 PF13238.1 CDI86041.1 - 1.3e-08 35.1 0.0 0.032 14.5 0.0 4.1 3 0 0 3 3 3 2 AAA domain AAA_17 PF13207.1 CDI86041.1 - 1.5e-08 35.5 0.0 0.0094 16.7 0.0 4.3 3 0 0 3 3 3 2 AAA domain AAA_33 PF13671.1 CDI86041.1 - 1.7e-07 31.2 0.0 0.13 12.1 0.0 3.9 3 0 0 3 3 3 2 AAA domain AAA_19 PF13245.1 CDI86041.1 - 2.9e-07 30.1 2.6 0.17 11.6 0.1 4.0 3 0 0 3 3 3 2 Part of AAA domain AAA_8 PF12780.2 CDI86041.1 - 6.8e-06 25.2 0.0 1.8e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_28 PF13521.1 CDI86041.1 - 2.6e-05 24.2 0.3 0.67 9.8 0.0 4.7 4 0 0 4 4 4 1 AAA domain NACHT PF05729.7 CDI86041.1 - 4.5e-05 23.1 3.2 0.87 9.2 0.0 5.3 5 1 0 5 5 4 2 NACHT domain AAA_29 PF13555.1 CDI86041.1 - 5.9e-05 22.5 0.7 0.031 13.7 0.1 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain Viral_helicase1 PF01443.13 CDI86041.1 - 0.0002 20.9 0.4 0.79 9.1 0.1 3.2 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase Miro PF08477.8 CDI86041.1 - 0.00027 21.3 0.2 1.3 9.5 0.0 3.8 3 0 0 3 3 3 1 Miro-like protein AAA_10 PF12846.2 CDI86041.1 - 0.00033 20.1 1.6 2.1 7.6 0.0 4.2 4 0 0 4 4 3 1 AAA-like domain RNA_helicase PF00910.17 CDI86041.1 - 0.00034 20.7 0.0 5.8 7.1 0.0 3.7 3 0 0 3 3 3 0 RNA helicase AAA_30 PF13604.1 CDI86041.1 - 0.00089 18.8 2.2 5.4 6.5 0.1 3.6 3 0 0 3 3 3 0 AAA domain AAA_25 PF13481.1 CDI86041.1 - 0.0016 17.8 11.0 0.16 11.3 0.1 4.8 5 0 0 5 5 5 2 AAA domain Mg_chelatase PF01078.16 CDI86041.1 - 0.0027 16.8 2.0 0.17 11.0 0.0 2.8 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI MMR_HSR1 PF01926.18 CDI86041.1 - 0.0037 17.1 0.0 0.48 10.4 0.1 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase Zeta_toxin PF06414.7 CDI86041.1 - 0.0048 16.0 2.1 0.59 9.2 0.1 3.6 3 0 0 3 3 3 1 Zeta toxin NTPase_1 PF03266.10 CDI86041.1 - 0.023 14.4 0.9 5.2 6.7 0.1 3.5 3 0 0 3 3 3 0 NTPase ABC_tran PF00005.22 CDI86041.1 - 0.032 14.5 0.0 2.5 8.3 0.0 3.4 2 0 0 2 2 2 0 ABC transporter UPF0079 PF02367.12 CDI86041.1 - 0.046 13.3 0.6 14 5.3 0.0 3.1 3 0 0 3 3 3 0 Uncharacterised P-loop hydrolase UPF0079 FtsK_SpoIIIE PF01580.13 CDI86041.1 - 0.052 13.0 2.9 0.15 11.5 0.0 3.0 3 0 0 3 3 3 0 FtsK/SpoIIIE family cobW PF02492.14 CDI86041.1 - 0.071 12.5 0.6 13 5.1 0.2 2.8 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain MobB PF03205.9 CDI86041.1 - 0.12 12.0 0.3 3.7 7.2 0.0 3.2 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_24 PF13479.1 CDI86041.1 - 6.8 6.2 6.1 12 5.3 0.1 3.2 3 0 0 3 3 3 0 AAA domain TcdA_TcdB PF12919.2 CDI86042.1 - 0.25 9.7 6.7 0.41 9.0 4.7 1.2 1 0 0 1 1 1 0 TcdA/TcdB catalytic glycosyltransferase domain Transposase_22 PF02994.9 CDI86042.1 - 0.83 8.0 11.5 1.4 7.3 8.0 1.3 1 0 0 1 1 1 0 L1 transposable element ArgK PF03308.11 CDI86042.1 - 0.91 8.2 4.8 1.3 7.6 3.3 1.2 1 0 0 1 1 1 0 ArgK protein OmpH PF03938.9 CDI86042.1 - 3.4 7.5 21.3 6.4 6.6 14.7 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Retrotrans_gag PF03732.12 CDI86042.1 - 5 7.2 11.2 26 4.9 7.8 2.3 2 1 0 2 2 2 0 Retrotransposon gag protein UCH PF00443.24 CDI86043.1 - 6.1e-48 163.2 0.0 1.2e-47 162.3 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CDI86043.1 - 1.7e-13 50.6 0.1 3.2e-06 26.7 0.0 3.0 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 CDI86043.1 - 2.8e-12 46.5 0.1 6.1e-11 42.2 0.0 3.0 3 0 0 3 3 3 1 Zn-finger in ubiquitin-hydrolases and other protein UBA PF00627.26 CDI86043.1 - 5.3e-11 42.0 0.5 1.3e-05 24.9 0.1 3.2 2 0 0 2 2 2 2 UBA/TS-N domain ArfGap PF01412.13 CDI86043.1 - 0.074 12.8 0.3 0.31 10.8 0.2 2.0 1 0 0 1 1 1 0 Putative GTPase activating protein for Arf SRP14 PF02290.10 CDI86044.1 - 1.4e-15 56.9 4.2 3.1e-15 55.8 0.0 2.6 2 1 0 2 2 2 1 Signal recognition particle 14kD protein DUF2735 PF10931.3 CDI86044.1 - 0.04 14.1 10.1 0.19 11.9 0.1 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF2735) FimP PF09766.4 CDI86044.1 - 0.053 12.5 7.5 0.086 11.8 5.2 1.3 1 0 0 1 1 1 0 Fms-interacting protein Peptidase_S49_N PF08496.5 CDI86044.1 - 8.9 6.0 9.5 15 5.3 6.6 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Activator_LAG-3 PF11498.3 CDI86045.1 - 0.0021 16.8 11.0 0.0021 16.8 7.6 2.4 2 0 0 2 2 2 1 Transcriptional activator LAG-3 DUF2217 PF10265.4 CDI86045.1 - 1.4 7.6 10.7 2.5 6.7 7.4 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) Phostensin_N PF13916.1 CDI86045.1 - 2.5 8.1 10.5 4.7 7.2 1.2 3.0 2 0 0 2 2 2 0 PP1-regulatory protein, Phostensin N-terminal VirC2 PF07181.6 CDI86046.1 - 0.0014 18.0 5.4 0.0017 17.8 3.7 1.0 1 0 0 1 1 1 1 VirC2 protein Suf PF05843.9 CDI86046.1 - 0.0038 16.9 13.9 0.0043 16.8 9.6 1.0 1 0 0 1 1 1 1 Suppressor of forked protein (Suf) FAM131 PF15010.1 CDI86046.1 - 0.0094 15.7 5.0 0.01 15.6 3.5 1.0 1 0 0 1 1 1 1 Putative cell signalling FimP PF09766.4 CDI86046.1 - 0.055 12.5 17.1 0.056 12.5 11.8 1.1 1 0 0 1 1 1 0 Fms-interacting protein DUF4355 PF14265.1 CDI86046.1 - 0.057 13.3 13.4 0.068 13.1 9.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4355) Peptidase_S49_N PF08496.5 CDI86046.1 - 0.12 12.1 5.4 0.12 12.2 3.7 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Pex16 PF08610.5 CDI86046.1 - 0.14 11.0 10.4 0.14 11.1 7.2 1.0 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) Dot_icm_IcmQ PF09475.5 CDI86046.1 - 0.15 11.3 5.3 0.17 11.1 3.7 1.1 1 0 0 1 1 1 0 Dot/Icm secretion system protein (dot_icm_IcmQ) SDA1 PF05285.7 CDI86046.1 - 0.17 11.0 9.3 0.2 10.9 6.4 1.0 1 0 0 1 1 1 0 SDA1 Band_3_cyto PF07565.8 CDI86046.1 - 0.19 11.2 7.4 0.18 11.2 5.1 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain DUF4011 PF13195.1 CDI86046.1 - 0.19 11.7 9.6 0.22 11.5 6.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4011) Herpes_TAF50 PF03326.8 CDI86046.1 - 0.22 10.4 15.8 0.24 10.3 11.0 1.0 1 0 0 1 1 1 0 Herpesvirus transcription activation factor (transactivator) CDC45 PF02724.9 CDI86046.1 - 0.29 9.1 7.3 0.31 9.0 5.1 1.0 1 0 0 1 1 1 0 CDC45-like protein Dala_Dala_lig_N PF01820.16 CDI86046.1 - 0.29 11.4 3.3 0.33 11.2 2.3 1.2 1 0 0 1 1 1 0 D-ala D-ala ligase N-terminus DUF2868 PF11067.3 CDI86046.1 - 0.36 9.9 8.3 0.38 9.8 5.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2868) TerB-C PF15615.1 CDI86046.1 - 0.38 11.0 9.1 0.41 10.8 6.3 1.0 1 0 0 1 1 1 0 TerB-C domain eIF-3_zeta PF05091.7 CDI86046.1 - 0.46 9.0 8.7 0.46 9.0 6.0 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DDRGK PF09756.4 CDI86046.1 - 0.48 9.8 12.7 0.51 9.7 8.8 1.1 1 0 0 1 1 1 0 DDRGK domain Y_phosphatase3 PF13350.1 CDI86046.1 - 0.51 10.5 2.9 0.56 10.4 2.0 1.0 1 0 0 1 1 1 0 Tyrosine phosphatase family DUF4175 PF13779.1 CDI86046.1 - 0.54 7.9 29.2 0.58 7.7 20.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) BRF1 PF07741.8 CDI86046.1 - 0.55 10.4 8.1 0.61 10.3 5.6 1.2 1 0 0 1 1 1 0 Brf1-like TBP-binding domain Spore_coat_CotO PF14153.1 CDI86046.1 - 0.62 9.4 14.4 0.64 9.4 10.0 1.1 1 0 0 1 1 1 0 Spore coat protein CotO Gti1_Pac2 PF09729.4 CDI86046.1 - 0.75 9.6 5.7 0.79 9.5 3.9 1.1 1 0 0 1 1 1 0 Gti1/Pac2 family Bud13 PF09736.4 CDI86046.1 - 0.82 9.9 12.4 0.89 9.8 8.6 1.1 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex Pex14_N PF04695.8 CDI86046.1 - 0.83 9.6 13.8 0.96 9.5 9.5 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF2126 PF09899.4 CDI86046.1 - 0.85 7.5 5.5 0.84 7.5 3.8 1.0 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) DUF4557 PF15101.1 CDI86046.1 - 0.89 9.3 18.6 0.93 9.2 12.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) Sec62 PF03839.11 CDI86046.1 - 0.99 8.7 3.9 0.99 8.7 2.7 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 Tim54 PF11711.3 CDI86046.1 - 1 7.8 7.2 1.1 7.8 5.0 1.0 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DUF3492 PF11997.3 CDI86046.1 - 1.1 8.7 4.8 1.3 8.5 3.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3492) DUF4496 PF14908.1 CDI86046.1 - 1.1 9.1 5.0 1.2 8.9 3.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4496) EIIBC-GUT_N PF03612.9 CDI86046.1 - 1.2 8.7 6.6 1.3 8.6 4.6 1.1 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus RR_TM4-6 PF06459.7 CDI86046.1 - 1.4 8.7 11.6 1.5 8.6 8.1 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF1800 PF08811.6 CDI86046.1 - 1.4 7.7 13.0 1.6 7.5 9.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1800) Med15 PF09606.5 CDI86046.1 - 1.5 6.9 31.7 1.5 6.9 22.0 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal FAM176 PF14851.1 CDI86046.1 - 1.5 8.4 5.8 1.7 8.3 4.0 1.1 1 0 0 1 1 1 0 FAM176 family FAM60A PF15396.1 CDI86046.1 - 1.5 8.5 5.6 1.6 8.4 3.9 1.1 1 0 0 1 1 1 0 Protein Family FAM60A Glyco_transf_15 PF01793.11 CDI86046.1 - 1.6 7.5 7.4 1.7 7.5 5.1 1.1 1 0 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase FCP1_C PF09309.5 CDI86046.1 - 1.7 7.8 14.0 2 7.6 9.7 1.1 1 0 0 1 1 1 0 FCP1, C-terminal Ctr PF04145.10 CDI86046.1 - 1.8 8.6 4.8 1.9 8.5 3.3 1.1 1 0 0 1 1 1 0 Ctr copper transporter family Paf1 PF03985.8 CDI86046.1 - 1.8 7.2 14.6 1.8 7.2 10.1 1.0 1 0 0 1 1 1 0 Paf1 PAT1 PF09770.4 CDI86046.1 - 1.8 6.6 27.7 2 6.5 19.2 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 OmpH PF03938.9 CDI86046.1 - 1.9 8.4 27.3 2 8.3 18.9 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Plasmodium_Vir PF05795.6 CDI86046.1 - 1.9 7.6 4.1 2 7.5 2.8 1.0 1 0 0 1 1 1 0 Plasmodium vivax Vir protein DUF775 PF05603.7 CDI86046.1 - 1.9 7.9 11.5 2.2 7.7 8.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF775) RNA_pol_Rbc25 PF08292.7 CDI86046.1 - 1.9 8.6 6.8 2.6 8.2 4.7 1.2 1 0 0 1 1 1 0 RNA polymerase III subunit Rpc25 DUF702 PF05142.7 CDI86046.1 - 2 8.5 8.0 2.1 8.4 5.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF702) LIM_bind PF01803.11 CDI86046.1 - 2.3 7.2 13.6 2.4 7.1 9.4 1.1 1 0 0 1 1 1 0 LIM-domain binding protein DUF3306 PF11748.3 CDI86046.1 - 2.3 8.8 11.1 2.7 8.6 7.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3306) PsiA PF06952.6 CDI86046.1 - 2.4 7.1 10.8 2.8 6.9 7.5 1.1 1 0 0 1 1 1 0 PsiA protein ATP-synt_E PF05680.7 CDI86046.1 - 2.4 8.1 10.3 3.1 7.8 7.1 1.1 1 0 0 1 1 1 0 ATP synthase E chain Folate_carrier PF01770.13 CDI86046.1 - 2.5 6.5 5.8 2.6 6.4 4.0 1.0 1 0 0 1 1 1 0 Reduced folate carrier DUF822 PF05687.8 CDI86046.1 - 2.5 8.4 8.0 2.6 8.3 5.5 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF822) Prog_receptor PF02161.10 CDI86046.1 - 3 6.5 8.9 3.4 6.3 6.2 1.0 1 0 0 1 1 1 0 Progesterone receptor Ycf1 PF05758.7 CDI86046.1 - 3.3 5.3 12.1 3.5 5.2 8.4 1.0 1 0 0 1 1 1 0 Ycf1 Agouti PF05039.7 CDI86046.1 - 3.4 8.0 6.6 4.3 7.7 4.6 1.2 1 0 0 1 1 1 0 Agouti protein YfhO PF09586.5 CDI86046.1 - 3.5 5.5 5.1 3.5 5.5 3.6 1.0 1 0 0 1 1 1 0 Bacterial membrane protein YfhO DUF3043 PF11241.3 CDI86046.1 - 3.5 7.1 6.6 4.2 6.9 4.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) DUF1682 PF07946.9 CDI86046.1 - 3.7 6.3 10.4 3.8 6.2 7.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) SIT PF15330.1 CDI86046.1 - 3.7 7.7 13.8 4.6 7.4 9.5 1.2 1 0 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT CagX PF03524.10 CDI86046.1 - 3.7 6.7 9.6 4.2 6.5 6.7 1.1 1 0 0 1 1 1 0 Conjugal transfer protein DUF912 PF06024.7 CDI86046.1 - 3.8 7.6 7.3 4.7 7.3 5.0 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) SeqA PF03925.8 CDI86046.1 - 3.8 7.1 9.3 4.2 7.0 6.4 1.1 1 0 0 1 1 1 0 SeqA protein Herpes_LMP2 PF07415.6 CDI86046.1 - 4.3 5.8 6.0 4.2 5.8 4.2 1.0 1 0 0 1 1 1 0 Gammaherpesvirus latent membrane protein (LMP2) protein AIF_C PF14721.1 CDI86046.1 - 4.5 7.5 8.0 4.9 7.3 5.6 1.1 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term FHIPEP PF00771.15 CDI86046.1 - 4.7 5.4 6.9 4.6 5.4 4.8 1.0 1 0 0 1 1 1 0 FHIPEP family DUF3276 PF11680.3 CDI86046.1 - 4.8 7.0 7.9 6.4 6.5 5.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3276) DUF106 PF01956.11 CDI86046.1 - 4.8 6.6 6.3 4.7 6.7 4.4 1.2 1 0 0 1 1 1 0 Integral membrane protein DUF106 DDHD PF02862.12 CDI86046.1 - 5.3 6.7 9.8 5.3 6.7 6.8 1.1 1 0 0 1 1 1 0 DDHD domain DUF3512 PF12024.3 CDI86046.1 - 5.4 6.2 10.4 7 5.8 7.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3512) RED_N PF07808.8 CDI86046.1 - 5.4 6.1 16.1 5.7 6.0 11.2 1.1 1 0 0 1 1 1 0 RED-like protein N-terminal region CPSF100_C PF13299.1 CDI86046.1 - 5.7 7.0 9.4 6.2 6.9 6.5 1.1 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Serinc PF03348.10 CDI86046.1 - 5.8 5.5 9.5 6 5.4 6.6 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) DHHW PF14286.1 CDI86046.1 - 5.8 6.1 7.7 6 6.0 5.3 1.0 1 0 0 1 1 1 0 DHHW protein Kei1 PF08552.6 CDI86046.1 - 6 6.4 8.9 6.8 6.3 6.2 1.1 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 BAF1_ABF1 PF04684.8 CDI86046.1 - 6 5.5 25.5 5.8 5.6 17.7 1.0 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Hid1 PF12722.2 CDI86046.1 - 7.1 4.1 14.2 7.7 4.0 9.8 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein TMEM51 PF15345.1 CDI86046.1 - 7.8 6.1 11.2 8.6 5.9 7.8 1.2 1 0 0 1 1 1 0 Transmembrane protein 51 Ndc1_Nup PF09531.5 CDI86046.1 - 7.9 4.7 9.4 7.4 4.8 6.5 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup ATAD4 PF15321.1 CDI86046.1 - 8.1 7.5 9.2 10 7.2 6.4 1.3 1 0 0 1 1 1 0 ATPase family AAA domain containing 4 TFIIA PF03153.8 CDI86046.1 - 8.6 6.1 20.9 9.3 6.0 14.5 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SprA-related PF12118.3 CDI86046.1 - 9.3 5.4 26.5 10 5.3 18.4 1.1 1 0 0 1 1 1 0 SprA-related family DUF4199 PF13858.1 CDI86046.1 - 9.6 6.0 8.7 11 5.9 6.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) OATP PF03137.15 CDI86046.1 - 9.8 4.0 7.8 10 4.0 5.4 1.0 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family K_channel_TID PF07941.6 CDI86047.1 - 0.00058 20.0 1.7 0.0026 17.9 1.2 2.1 1 0 0 1 1 1 1 Potassium channel Kv1.4 tandem inactivation domain Raftlin PF15250.1 CDI86047.1 - 3.1 6.2 18.1 3.9 5.8 12.5 1.3 1 0 0 1 1 1 0 Raftlin DUF1042 PF06294.6 CDI86048.1 - 3.3e-18 65.7 1.1 3.9e-18 65.5 0.7 1.1 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1042) CAMSAP_CH PF11971.3 CDI86048.1 - 1.8e-06 27.5 0.0 3.2e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 CAMSAP CH domain DUF3972 PF13118.1 CDI86048.1 - 0.2 11.7 6.4 0.96 9.5 4.5 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3972) Mnd1 PF03962.10 CDI86048.1 - 0.83 9.2 8.6 1.2 8.7 6.0 1.2 1 0 0 1 1 1 0 Mnd1 family CDC37_N PF03234.9 CDI86048.1 - 5 7.4 7.0 1 9.6 1.9 1.8 1 1 1 2 2 2 0 Cdc37 N terminal kinase binding Bap31 PF05529.7 CDI86048.1 - 7.2 6.0 7.7 11 5.4 5.3 1.3 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like DUF1635 PF07795.6 CDI86049.1 - 0.0019 17.6 8.4 0.002 17.5 5.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1635) SR-25 PF10500.4 CDI86049.1 - 0.0022 17.5 13.4 0.0024 17.3 9.3 1.0 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein DUF4228 PF14009.1 CDI86049.1 - 0.011 15.8 5.3 0.013 15.6 3.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4228) RD3 PF14473.1 CDI86049.1 - 0.027 13.9 0.5 0.027 13.9 0.3 1.2 1 0 0 1 1 1 0 RD3 protein CDK2AP PF09806.4 CDI86049.1 - 0.048 13.8 8.7 0.051 13.8 6.1 1.0 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein DUF3399 PF11879.3 CDI86049.1 - 0.076 13.2 3.7 0.087 13.0 2.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3399) MYT1 PF08474.6 CDI86049.1 - 0.095 12.1 5.7 0.1 12.1 4.0 1.0 1 0 0 1 1 1 0 Myelin transcription factor 1 APC_CDC26 PF10471.4 CDI86049.1 - 0.11 13.2 11.2 0.14 12.8 7.7 1.2 1 0 0 1 1 1 0 Anaphase-promoting complex APC subunit 1 Pap_E4 PF02711.9 CDI86049.1 - 0.13 13.1 3.4 0.14 13.0 2.4 1.1 1 0 0 1 1 1 0 E4 protein Conotoxin PF02950.12 CDI86049.1 - 0.24 12.2 1.1 0.27 12.0 0.8 1.2 1 0 0 1 1 1 0 Conotoxin DUF1908 PF08926.6 CDI86049.1 - 0.5 9.0 4.4 0.51 9.0 3.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1908) DUF4557 PF15101.1 CDI86049.1 - 0.58 9.9 5.5 0.64 9.8 3.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) RAP1 PF07218.6 CDI86049.1 - 0.85 7.6 5.4 0.8 7.7 3.7 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DUF4657 PF15552.1 CDI86049.1 - 0.89 8.7 11.1 0.95 8.6 7.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4657) DUF2051 PF09738.4 CDI86049.1 - 1.2 8.3 9.9 1.3 8.2 6.8 1.0 1 0 0 1 1 1 0 Double stranded RNA binding protein (DUF2051) Dehydrin PF00257.14 CDI86049.1 - 5.1 7.4 6.4 6.9 6.9 4.4 1.2 1 0 0 1 1 1 0 Dehydrin Phostensin_N PF13916.1 CDI86049.1 - 5.7 6.9 7.9 9.4 6.2 5.5 1.4 1 0 0 1 1 1 0 PP1-regulatory protein, Phostensin N-terminal DUF1510 PF07423.6 CDI86050.1 - 2.9e-05 23.5 28.4 0.00014 21.3 11.1 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1510) Ycf1 PF05758.7 CDI86050.1 - 0.027 12.2 31.5 0.0066 14.2 12.4 2.1 2 0 0 2 2 2 0 Ycf1 Sporozoite_P67 PF05642.6 CDI86050.1 - 0.027 12.3 11.9 0.042 11.7 8.3 1.3 1 1 0 1 1 1 0 Sporozoite P67 surface antigen SPX PF03105.14 CDI86050.1 - 0.058 13.1 26.4 0.46 10.2 10.9 2.2 2 0 0 2 2 2 0 SPX domain DUF4045 PF13254.1 CDI86050.1 - 0.089 12.0 49.5 0.19 10.9 22.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4045) Mem_trans PF03547.13 CDI86050.1 - 2.1 6.5 13.8 0.13 10.5 3.9 2.1 2 0 0 2 2 2 0 Membrane transport protein Hid1 PF12722.2 CDI86050.1 - 2.9 5.4 42.0 0.31 8.6 2.2 2.1 2 0 0 2 2 2 0 High-temperature-induced dauer-formation protein eIF-3_zeta PF05091.7 CDI86050.1 - 9.5 4.7 52.7 0.62 8.6 8.1 2.1 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Dynamin_N PF00350.18 CDI86051.1 - 4.2e-09 36.4 0.0 7.2e-09 35.6 0.0 1.3 1 1 0 1 1 1 1 Dynamin family Miro PF08477.8 CDI86051.1 - 0.00089 19.7 0.0 0.0015 19.0 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein AAA_28 PF13521.1 CDI86051.1 - 0.0013 18.6 0.0 0.0032 17.4 0.0 1.6 2 0 0 2 2 2 1 AAA domain GTP_EFTU PF00009.22 CDI86051.1 - 0.0065 15.9 0.0 2.8 7.3 0.0 2.1 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain cobW PF02492.14 CDI86051.1 - 0.033 13.6 0.0 2.8 7.3 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Septin PF00735.13 CDI86051.1 - 0.12 11.3 0.0 0.17 10.8 0.0 1.2 1 0 0 1 1 1 0 Septin SR-25 PF10500.4 CDI86053.1 - 0.00044 19.8 56.6 0.0033 16.9 17.9 2.1 1 1 1 2 2 2 2 Nuclear RNA-splicing-associated protein FA_desaturase PF00487.19 CDI86053.1 - 0.011 15.1 0.0 0.017 14.5 0.0 1.2 1 0 0 1 1 1 0 Fatty acid desaturase ETRAMP PF09716.5 CDI86053.1 - 1.5 8.7 14.8 0.29 11.1 2.4 2.6 2 1 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) Utp14 PF04615.8 CDI86053.1 - 5.8 4.9 41.4 6.4 4.7 28.7 1.0 1 0 0 1 1 1 0 Utp14 protein SR-25 PF10500.4 CDI86054.1 - 0.00047 19.6 17.7 0.00052 19.5 12.3 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Suf PF05843.9 CDI86054.1 - 0.25 11.0 25.3 0.25 11.0 17.5 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DDHD PF02862.12 CDI86054.1 - 0.85 9.3 16.7 0.92 9.2 11.6 1.1 1 0 0 1 1 1 0 DDHD domain FLO_LFY PF01698.11 CDI86054.1 - 1.4 7.7 16.0 1.4 7.6 11.1 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein PPP4R2 PF09184.6 CDI86054.1 - 1.4 8.4 14.5 1.5 8.3 10.0 1.0 1 0 0 1 1 1 0 PPP4R2 2OG-FeII_Oxy_5 PF13759.1 CDI86054.1 - 1.5 9.1 8.7 2.4 8.5 6.1 1.3 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase CDC45 PF02724.9 CDI86054.1 - 1.7 6.6 16.8 1.7 6.5 11.6 1.0 1 0 0 1 1 1 0 CDC45-like protein FAM60A PF15396.1 CDI86054.1 - 2.6 7.7 17.9 3.1 7.4 12.4 1.1 1 0 0 1 1 1 0 Protein Family FAM60A BNIP3 PF06553.7 CDI86054.1 - 2.6 7.3 18.2 3 7.1 12.6 1.1 1 0 0 1 1 1 0 BNIP3 AUX_IAA PF02309.11 CDI86054.1 - 2.7 7.6 16.4 2.9 7.5 11.4 1.2 1 0 0 1 1 1 0 AUX/IAA family Activator_LAG-3 PF11498.3 CDI86054.1 - 2.9 6.5 44.9 3.3 6.3 31.1 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 SAGA-Tad1 PF12767.2 CDI86054.1 - 3.2 7.3 22.5 3.4 7.2 15.6 1.0 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit eIF-3_zeta PF05091.7 CDI86054.1 - 3.4 6.1 19.9 3.4 6.1 13.8 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Presenilin PF01080.12 CDI86054.1 - 3.8 6.2 17.9 4.4 6.0 12.4 1.1 1 0 0 1 1 1 0 Presenilin Spore_coat_CotO PF14153.1 CDI86054.1 - 4 6.8 25.6 4.3 6.7 17.8 1.1 1 0 0 1 1 1 0 Spore coat protein CotO RR_TM4-6 PF06459.7 CDI86054.1 - 4.1 7.2 17.8 4.3 7.1 12.3 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 MRP-S31 PF15433.1 CDI86054.1 - 4.3 6.6 22.1 4.5 6.6 15.3 1.1 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 DUF2992 PF11208.3 CDI86054.1 - 5.5 6.9 22.7 7.2 6.5 15.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2992) BTV_NS2 PF04514.7 CDI86054.1 - 5.6 5.7 12.2 5.6 5.7 8.5 1.0 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Peptidase_S15 PF02129.13 CDI86054.1 - 5.7 6.2 16.2 6.7 6.0 11.2 1.2 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) DUF4446 PF14584.1 CDI86054.1 - 5.9 6.7 7.6 7.8 6.3 5.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) GAGA_bind PF06217.7 CDI86054.1 - 6.3 6.6 18.7 6.6 6.6 13.0 1.0 1 0 0 1 1 1 0 GAGA binding protein-like family SOBP PF15279.1 CDI86054.1 - 6.6 7.0 22.1 7.3 6.8 15.3 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein Med15 PF09606.5 CDI86054.1 - 8.1 4.4 56.1 9.7 4.2 38.9 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Apt1 PF10351.4 CDI86054.1 - 9.3 4.9 15.2 9.3 4.9 10.5 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain KAP_NTPase PF07693.9 CDI86055.1 - 0.038 12.9 2.1 0.1 11.5 0.4 2.0 1 1 1 2 2 2 0 KAP family P-loop domain DUF3464 PF11947.3 CDI86055.1 - 0.043 13.2 0.3 0.043 13.2 0.2 3.4 1 1 2 3 3 3 0 Protein of unknown function (DUF3464) PBP1_TM PF14812.1 CDI86055.1 - 0.23 11.7 11.1 0.42 10.9 1.1 3.3 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal FAM101 PF15068.1 CDI86055.1 - 1 8.7 13.6 0.35 10.2 0.9 3.3 2 1 2 4 4 4 0 FAM101 family DUF3899 PF13038.1 CDI86055.1 - 1.1 9.5 6.6 14 5.9 0.9 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF3899) CbiJ PF02571.9 CDI86055.1 - 1.2 8.3 15.0 2.2 7.5 1.6 2.5 1 1 0 2 2 2 0 Precorrin-6x reductase CbiJ/CobK Ribosomal_60s PF00428.14 CDI86055.1 - 1.4 9.3 48.6 2.3 8.6 1.9 4.2 4 0 0 4 4 4 0 60s Acidic ribosomal protein DASH_Dad2 PF08654.5 CDI86055.1 - 5.2 7.1 20.7 2.4 8.1 0.3 3.5 4 0 0 4 4 4 0 DASH complex subunit Dad2 DUF4045 PF13254.1 CDI86058.1 - 2.3 7.3 34.1 3.5 6.7 23.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) PAT1 PF09770.4 CDI86058.1 - 3.5 5.7 106.0 4.2 5.4 73.4 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 CDC45 PF02724.9 CDI86058.1 - 8.1 4.3 37.5 11 3.9 26.0 1.2 1 0 0 1 1 1 0 CDC45-like protein Med15 PF09606.5 CDI86059.1 - 0.82 7.7 12.1 0.87 7.7 8.4 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Miff PF05644.6 CDI86060.1 - 0.0025 17.4 0.5 0.0026 17.4 0.4 1.0 1 0 0 1 1 1 1 Mitochondrial and peroxisomal fission factor Mff BAF1_ABF1 PF04684.8 CDI86060.1 - 0.0026 16.6 14.2 0.0033 16.3 9.9 1.1 1 0 0 1 1 1 1 BAF1 / ABF1 chromatin reorganising factor CDK2AP PF09806.4 CDI86060.1 - 0.0033 17.6 8.4 0.004 17.4 5.8 1.1 1 0 0 1 1 1 1 Cyclin-dependent kinase 2-associated protein Tir_receptor_N PF07490.6 CDI86060.1 - 0.025 14.2 0.6 0.028 14.0 0.4 1.0 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) N-terminus Herpes_TAF50 PF03326.8 CDI86060.1 - 0.062 12.2 10.2 0.072 12.0 7.1 1.0 1 0 0 1 1 1 0 Herpesvirus transcription activation factor (transactivator) Med15 PF09606.5 CDI86060.1 - 0.063 11.4 20.1 0.073 11.2 14.0 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Spt20 PF12090.3 CDI86060.1 - 0.16 11.3 2.7 0.17 11.2 1.8 1.1 1 0 0 1 1 1 0 Spt20 family APC_CDC26 PF10471.4 CDI86060.1 - 0.35 11.6 10.6 0.68 10.7 7.4 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex APC subunit 1 DUF2802 PF10975.3 CDI86060.1 - 1.5 8.6 12.0 2.9 7.7 8.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2802) PAT1 PF09770.4 CDI86060.1 - 1.7 6.8 14.2 1.7 6.7 9.8 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF3138 PF11336.3 CDI86060.1 - 9.5 4.2 14.0 11 4.0 9.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) FAM176 PF14851.1 CDI86061.1 - 3 7.5 9.2 2.1 8.0 0.0 2.5 2 0 0 2 2 2 0 FAM176 family Zn_peptidase PF04228.8 CDI86061.1 - 3.1 6.9 23.2 0.047 12.9 1.7 2.4 2 0 0 2 2 2 0 Putative neutral zinc metallopeptidase TraV PF09676.5 CDI86062.1 - 0.074 13.7 0.4 0.1 13.2 0.3 1.4 1 0 0 1 1 1 0 Type IV conjugative transfer system lipoprotein (TraV) DUF4407 PF14362.1 CDI86062.1 - 0.6 9.0 2.6 0.83 8.5 1.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) VEK-30 PF12107.3 CDI86062.1 - 3.7 7.3 7.2 5.6 6.7 0.6 2.8 2 0 0 2 2 2 0 Plasminogen (Pg) ligand in fibrinolytic pathway ATG13 PF10033.4 CDI86063.1 - 0.36 10.2 5.5 0.4 10.0 3.8 1.1 1 0 0 1 1 1 0 Autophagy-related protein 13 Herpes_UL87 PF03043.9 CDI86063.1 - 1.3 7.3 10.3 1.2 7.4 7.1 1.0 1 0 0 1 1 1 0 Herpesvirus UL87 family DUF2868 PF11067.3 CDI86063.1 - 1.5 7.9 18.7 1.6 7.8 13.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2868) Kei1 PF08552.6 CDI86063.1 - 3 7.4 6.7 3.6 7.1 4.7 1.2 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 Lipoprotein_X PF03305.8 CDI86063.1 - 3.9 6.7 11.8 4 6.7 8.2 1.0 1 0 0 1 1 1 0 Mycoplasma MG185/MG260 protein FNIP_N PF14636.1 CDI86063.1 - 4.1 7.8 13.1 5.4 7.5 9.1 1.3 1 0 0 1 1 1 0 Folliculin-interacting protein N-terminus Tyrosinase PF00264.15 CDI86063.1 - 4.5 7.3 8.9 4.7 7.2 6.1 1.1 1 0 0 1 1 1 0 Common central domain of tyrosinase DUF1675 PF07897.6 CDI86063.1 - 5.9 6.6 8.8 5.9 6.6 6.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) DDHD PF02862.12 CDI86063.1 - 6.1 6.5 12.2 6.9 6.3 8.4 1.1 1 0 0 1 1 1 0 DDHD domain BTV_NS2 PF04514.7 CDI86063.1 - 8.6 5.1 13.4 9.4 5.0 9.3 1.0 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 FAM60A PF15396.1 CDI86063.1 - 8.9 5.9 12.1 9.6 5.8 8.4 1.1 1 0 0 1 1 1 0 Protein Family FAM60A DUF1168 PF06658.7 CDI86063.1 - 9.1 5.7 19.8 11 5.5 13.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) Neur_chan_memb PF02932.11 CDI86063.1 - 9.1 6.0 9.9 10 5.9 6.9 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DHHW PF14286.1 CDI86063.1 - 9.6 5.4 7.8 9.4 5.4 5.4 1.0 1 0 0 1 1 1 0 DHHW protein Mo25 PF08569.6 CDI86063.1 - 9.9 5.0 13.0 11 4.9 9.0 1.0 1 0 0 1 1 1 0 Mo25-like Peptidase_S49_N PF08496.5 CDI86064.1 - 2.9 7.6 20.9 3.4 7.4 14.5 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal HSP70 PF00012.15 CDI86064.1 - 5.1 4.8 15.7 5.1 4.8 10.9 1.0 1 0 0 1 1 1 0 Hsp70 protein CAF-1_p150 PF11600.3 CDI86065.1 - 0.0022 17.4 25.0 0.0022 17.4 17.3 5.9 6 1 0 6 6 6 3 Chromatin assembly factor 1 complex p150 subunit, N-terminal FAM195 PF14799.1 CDI86065.1 - 0.0034 17.2 5.4 0.0034 17.2 3.8 6.6 7 1 0 7 7 7 1 FAM195 family DUF2407_C PF13373.1 CDI86065.1 - 0.0055 16.6 2.5 0.0055 16.6 1.7 4.8 5 0 0 5 5 5 1 DUF2407 C-terminal domain DUF2722 PF10846.3 CDI86065.1 - 0.02 13.9 0.2 0.02 13.9 0.1 6.9 5 2 1 6 6 6 0 Protein of unknown function (DUF2722) Ycf1 PF05758.7 CDI86065.1 - 1.7 6.2 36.5 0.011 13.4 7.6 3.5 4 0 0 4 4 4 0 Ycf1 SF3b10 PF07189.6 CDI86066.1 - 2.7e-20 71.9 0.0 4.7e-20 71.1 0.0 1.3 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) DUF3138 PF11336.3 CDI86066.1 - 0.058 11.5 2.9 0.053 11.6 2.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Ribosomal_60s PF00428.14 CDI86066.1 - 3.9 7.9 25.0 2.1e+02 2.3 17.3 2.1 1 1 0 1 1 1 0 60s Acidic ribosomal protein IncA PF04156.9 CDI86067.1 - 0.0006 19.4 8.8 0.00074 19.1 6.1 1.1 1 0 0 1 1 1 1 IncA protein VIT1 PF01988.14 CDI86067.1 - 0.024 14.1 7.4 0.029 13.8 5.1 1.0 1 0 0 1 1 1 0 VIT family Activator_LAG-3 PF11498.3 CDI86067.1 - 0.025 13.3 30.2 0.027 13.2 20.9 1.0 1 0 0 1 1 1 0 Transcriptional activator LAG-3 CAF-1_p150 PF11600.3 CDI86067.1 - 0.039 13.3 10.0 0.039 13.3 6.9 1.0 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal FimP PF09766.4 CDI86067.1 - 0.085 11.9 13.6 0.08 11.9 9.4 1.0 1 0 0 1 1 1 0 Fms-interacting protein Ctr PF04145.10 CDI86067.1 - 0.15 12.0 4.5 0.17 11.9 3.1 1.1 1 0 0 1 1 1 0 Ctr copper transporter family AAA_23 PF13476.1 CDI86067.1 - 0.48 10.7 9.1 0.51 10.6 6.3 1.0 1 0 0 1 1 1 0 AAA domain FHIPEP PF00771.15 CDI86067.1 - 0.61 8.3 9.5 0.62 8.3 6.6 1.0 1 0 0 1 1 1 0 FHIPEP family Spt20 PF12090.3 CDI86067.1 - 0.88 8.8 8.9 0.93 8.8 6.2 1.3 1 0 0 1 1 1 0 Spt20 family DUF2232 PF09991.4 CDI86067.1 - 1.1 8.1 6.6 1.2 8.0 4.6 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) Suf PF05843.9 CDI86067.1 - 2.1 8.0 17.5 2 8.0 12.2 1.0 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) R_equi_Vir PF05526.6 CDI86067.1 - 2.1 7.9 14.8 2.4 7.7 10.3 1.1 1 0 0 1 1 1 0 Rhodococcus equi virulence-associated protein Gag_spuma PF03276.9 CDI86067.1 - 2.3 6.4 15.4 2.2 6.4 10.6 1.1 1 0 0 1 1 1 0 Spumavirus gag protein Med15 PF09606.5 CDI86067.1 - 2.3 6.2 36.6 2.4 6.2 25.4 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal TPP_enzyme_N PF02776.13 CDI86067.1 - 2.3 7.6 12.9 2.8 7.4 9.0 1.1 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain FAM222A PF15258.1 CDI86067.1 - 2.4 7.2 19.8 2.7 7.0 13.7 1.1 1 0 0 1 1 1 0 Protein family of FAM222A RAB3GAP2_N PF14655.1 CDI86067.1 - 2.8 6.8 11.9 3 6.7 8.3 1.1 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Serinc PF03348.10 CDI86067.1 - 3.1 6.4 10.7 3.2 6.3 7.4 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) OATP PF03137.15 CDI86067.1 - 3.2 5.7 5.5 3 5.7 3.8 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Glt_symporter PF03616.9 CDI86067.1 - 3.6 5.9 5.8 4.2 5.7 4.0 1.2 1 0 0 1 1 1 0 Sodium/glutamate symporter DUF2215 PF10225.4 CDI86067.1 - 3.8 6.8 6.2 4 6.8 4.3 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) DUF4207 PF13904.1 CDI86067.1 - 4.4 6.6 22.8 4.6 6.5 15.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4207) MDFI PF15316.1 CDI86067.1 - 7.3 6.5 11.0 7.7 6.4 7.7 1.0 1 0 0 1 1 1 0 MyoD family inhibitor DUF4367 PF14285.1 CDI86067.1 - 8.5 5.6 7.4 12 5.1 5.1 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4367) SR-25 PF10500.4 CDI86068.1 - 0.00021 20.8 11.6 0.00021 20.8 8.1 2.2 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein ODV-E18 PF10717.4 CDI86068.1 - 0.00082 18.7 1.9 0.00082 18.7 1.3 2.4 2 1 0 2 2 1 1 Occlusion-derived virus envelope protein ODV-E18 CDK2AP PF09806.4 CDI86068.1 - 0.0013 19.0 13.3 0.0017 18.6 9.3 1.3 1 0 0 1 1 1 1 Cyclin-dependent kinase 2-associated protein zf-C4H2 PF10146.4 CDI86068.1 - 0.018 15.0 3.2 0.026 14.5 2.2 1.2 1 0 0 1 1 1 0 Zinc finger-containing protein Rifin_STEVOR PF02009.11 CDI86068.1 - 0.062 12.9 3.4 0.084 12.4 2.3 1.2 1 0 0 1 1 1 0 Rifin/stevor family Zip PF02535.17 CDI86068.1 - 0.11 11.5 1.6 0.13 11.2 1.1 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter DUF2413 PF10310.4 CDI86068.1 - 0.14 10.9 7.4 0.15 10.8 5.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) Suf PF05843.9 CDI86068.1 - 0.19 11.4 2.9 0.2 11.3 2.0 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF572 PF04502.8 CDI86068.1 - 0.26 10.4 5.6 0.32 10.1 3.9 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) Cyclin_C PF02984.14 CDI86068.1 - 0.41 10.6 8.7 0.14 12.0 2.3 2.5 2 1 1 3 3 3 0 Cyclin, C-terminal domain BaxI_1 PF12811.2 CDI86068.1 - 0.43 9.7 2.6 0.55 9.3 1.8 1.1 1 0 0 1 1 1 0 Bax inhibitor 1 like Aminotran_1_2 PF00155.16 CDI86068.1 - 0.51 9.2 4.0 0.43 9.4 1.8 1.5 2 0 0 2 2 2 0 Aminotransferase class I and II TFIIA PF03153.8 CDI86068.1 - 0.54 10.0 7.6 0.59 9.9 5.3 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Macoilin PF09726.4 CDI86068.1 - 1.1 7.4 10.7 1.2 7.2 7.4 1.2 1 0 0 1 1 1 0 Transmembrane protein Period_C PF12114.3 CDI86068.1 - 1.6 8.2 14.3 0.18 11.4 6.1 2.0 2 0 0 2 2 2 0 Period protein 2/3C-terminal region Scs3p PF10261.4 CDI86070.1 - 0.31 10.0 2.2 0.58 9.1 1.5 1.6 1 0 0 1 1 1 0 Inositol phospholipid synthesis and fat-storage-inducing TM HATPase_c_3 PF13589.1 CDI86070.1 - 0.31 10.6 1.9 0.86 9.2 0.6 2.2 1 1 1 2 2 2 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Wzz PF02706.10 CDI86070.1 - 1.4 8.7 5.8 3.2 7.5 4.0 1.6 1 0 0 1 1 1 0 Chain length determinant protein Tryp_alpha_amyl PF00234.17 CDI86071.1 - 0.15 12.2 5.9 0.32 11.2 1.6 2.2 2 0 0 2 2 2 0 Protease inhibitor/seed storage/LTP family Macoilin PF09726.4 CDI86071.1 - 0.21 9.8 7.6 0.27 9.4 5.2 1.0 1 0 0 1 1 1 0 Transmembrane protein GET2 PF08690.5 CDI86071.1 - 0.27 10.4 8.3 0.33 10.1 5.8 1.1 1 0 0 1 1 1 0 GET complex subunit GET2 Activator_LAG-3 PF11498.3 CDI86075.1 - 0.002 16.9 22.3 0.002 16.9 15.5 2.2 2 0 0 2 2 2 1 Transcriptional activator LAG-3 DASH_Spc19 PF08287.6 CDI86075.1 - 1.3 8.6 26.1 0.61 9.6 7.2 2.2 2 0 0 2 2 2 0 Spc19 Peptidase_S49_N PF08496.5 CDI86075.1 - 1.4 8.6 16.5 0.047 13.4 2.4 2.3 2 0 0 2 2 2 0 Peptidase family S49 N-terminal PLRV_ORF5 PF01690.12 CDI86075.1 - 3.1 6.8 21.0 3.7 6.5 14.6 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein DUF3371 PF11851.3 CDI86075.1 - 5.8 7.6 25.3 1.1 9.9 6.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3371) 60KD_IMP PF02096.15 CDI86076.1 - 0.0034 17.0 3.3 0.096 12.3 0.1 2.4 2 0 0 2 2 2 2 60Kd inner membrane protein DUF4557 PF15101.1 CDI86076.1 - 0.028 14.2 10.7 0.1 12.3 1.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4557) CD20 PF04103.10 CDI86076.1 - 1.8 8.4 7.4 1.4 8.8 0.6 2.5 2 0 0 2 2 2 0 CD20-like family Corona_nucleoca PF00937.13 CDI86076.1 - 4.3 6.1 17.4 0.25 10.2 4.0 2.1 2 0 0 2 2 2 0 Coronavirus nucleocapsid protein Ycf1 PF05758.7 CDI86077.1 - 0.28 8.8 6.4 0.32 8.6 4.4 1.1 1 0 0 1 1 1 0 Ycf1 DRY_EERY PF09750.4 CDI86077.1 - 0.43 10.6 13.0 1.7 8.7 9.0 2.0 1 0 0 1 1 1 0 Alternative splicing regulator Afi1 PF07792.7 CDI86077.1 - 3.5 7.6 14.3 0.84 9.6 6.6 2.2 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking DUF4647 PF15504.1 CDI86077.1 - 4.9 5.8 19.3 7.1 5.3 13.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4647) Hid1 PF12722.2 CDI86077.1 - 8 4.0 16.6 11 3.5 11.5 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF2361 PF10153.4 CDI86077.1 - 8 6.6 20.4 3.7 7.7 12.1 1.8 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2361) Spore_coat_CotO PF14153.1 CDI86078.1 - 0.011 15.2 13.0 0.011 15.2 9.0 1.1 1 0 0 1 1 1 0 Spore coat protein CotO GAGA_bind PF06217.7 CDI86078.1 - 0.026 14.4 8.1 0.025 14.5 5.6 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family Inositol_P PF00459.20 CDI86078.1 - 0.029 13.6 0.4 0.034 13.4 0.3 1.1 1 0 0 1 1 1 0 Inositol monophosphatase family DUF4175 PF13779.1 CDI86078.1 - 0.035 11.8 33.3 0.039 11.6 23.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) DUF3337 PF11816.3 CDI86078.1 - 0.57 9.5 9.1 0.68 9.2 6.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3337) TGF_beta PF00019.15 CDI86078.1 - 0.79 10.0 10.7 0.59 10.4 6.1 1.7 1 1 1 2 2 2 0 Transforming growth factor beta like domain DUF572 PF04502.8 CDI86078.1 - 1.3 8.1 14.9 1.7 7.7 10.3 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Neur_chan_memb PF02932.11 CDI86078.1 - 2.2 8.1 9.7 2.5 7.9 6.7 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region PAT1 PF09770.4 CDI86078.1 - 2.2 6.4 40.3 2.5 6.2 28.0 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TFIIA PF03153.8 CDI86078.1 - 3.2 7.5 25.7 3.9 7.2 17.8 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Hist_deacetyl PF00850.14 CDI86078.1 - 3.2 6.9 7.2 3.9 6.6 5.0 1.2 1 0 0 1 1 1 0 Histone deacetylase domain eIF-3_zeta PF05091.7 CDI86078.1 - 3.8 6.0 16.0 4.6 5.7 11.1 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF4484 PF14831.1 CDI86078.1 - 3.9 7.5 8.4 5 7.1 5.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4484) Hid1 PF12722.2 CDI86078.1 - 4.1 4.9 14.1 4.7 4.7 9.8 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Ndc1_Nup PF09531.5 CDI86078.1 - 4.2 5.6 12.0 4.9 5.4 8.3 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF4045 PF13254.1 CDI86078.1 - 4.4 6.4 13.3 5.6 6.1 9.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) DUF1178 PF06676.6 CDI86078.1 - 4.4 7.4 14.2 7.2 6.7 9.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1178) BTV_NS2 PF04514.7 CDI86078.1 - 6 5.6 12.6 7.3 5.3 8.7 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 hDGE_amylase PF14701.1 CDI86078.1 - 6.7 5.4 12.9 8.4 5.1 8.9 1.0 1 0 0 1 1 1 0 glucanotransferase domain of human glycogen debranching enzyme Mgr1 PF08602.5 CDI86078.1 - 8.7 5.2 7.9 11 4.9 5.5 1.2 1 0 0 1 1 1 0 Mgr1-like, i-AAA protease complex subunit MIP-T3 PF10243.4 CDI86079.1 - 5.5 5.3 98.0 7.6 4.8 67.9 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 RRM_1 PF00076.17 CDI86080.1 - 1.6e-16 59.7 0.0 0.0003 20.3 0.0 4.7 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CDI86080.1 - 4.7e-16 58.5 0.0 7.8e-05 22.5 0.0 4.6 4 0 0 4 4 4 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CDI86080.1 - 1.1e-10 41.1 0.0 5.1e-05 23.0 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Spore_coat_CotO PF14153.1 CDI86080.1 - 0.0061 16.0 30.7 0.0061 16.0 21.3 5.7 4 3 0 4 4 4 1 Spore coat protein CotO Utp11 PF03998.8 CDI86080.1 - 0.0075 16.1 10.8 0.0075 16.1 7.5 4.5 4 0 0 4 4 4 1 Utp11 protein SieB PF14163.1 CDI86080.1 - 0.5 9.9 7.6 0.21 11.1 1.6 2.8 2 0 0 2 2 2 0 Superinfection exclusion protein B AF-4 PF05110.8 CDI86081.1 - 0.0077 14.1 20.1 0.0094 13.8 13.9 1.1 1 0 0 1 1 1 1 AF-4 proto-oncoprotein UPF0029 PF01205.14 CDI86081.1 - 0.023 14.3 2.2 0.043 13.5 1.5 1.5 1 0 0 1 1 1 0 Uncharacterized protein family UPF0029 Cwf_Cwc_15 PF04889.7 CDI86081.1 - 0.024 14.3 12.9 0.029 14.0 8.9 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein MAT1 PF06391.8 CDI86081.1 - 0.035 13.6 14.4 0.047 13.2 9.9 1.2 1 0 0 1 1 1 0 CDK-activating kinase assembly factor MAT1 TCTP PF00838.12 CDI86081.1 - 0.11 12.4 0.2 0.16 11.9 0.2 1.2 1 0 0 1 1 1 0 Translationally controlled tumour protein DUF2217 PF10265.4 CDI86081.1 - 0.12 11.1 12.8 0.15 10.8 8.9 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) DUF2813 PF11398.3 CDI86081.1 - 0.16 11.0 11.7 0.18 10.8 8.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2813) NAD_binding_5 PF07994.7 CDI86081.1 - 0.16 11.4 3.2 0.19 11.1 2.2 1.0 1 0 0 1 1 1 0 Myo-inositol-1-phosphate synthase DUF572 PF04502.8 CDI86081.1 - 0.22 10.7 14.8 0.27 10.3 10.2 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Allexi_40kDa PF05549.6 CDI86081.1 - 0.23 10.6 13.2 0.33 10.2 9.2 1.2 1 0 0 1 1 1 0 Allexivirus 40kDa protein Put_Phosphatase PF06888.7 CDI86081.1 - 0.3 10.2 3.1 0.38 9.8 2.2 1.1 1 0 0 1 1 1 0 Putative Phosphatase Peptidase_U57 PF05582.7 CDI86081.1 - 0.44 9.4 5.7 0.5 9.2 4.0 1.2 1 0 0 1 1 1 0 YabG peptidase U57 PP2C_2 PF13672.1 CDI86081.1 - 0.51 9.6 8.4 0.9 8.8 5.8 1.4 1 0 0 1 1 1 0 Protein phosphatase 2C RAP1 PF07218.6 CDI86081.1 - 1.1 7.2 6.0 1.4 6.8 4.2 1.3 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DUF2052 PF09747.4 CDI86081.1 - 1.6 8.6 13.3 2.2 8.1 9.3 1.3 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) DUF508 PF04370.7 CDI86081.1 - 2.4 7.7 14.6 6.3 6.3 7.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF508) Lipase_GDSL_3 PF14606.1 CDI86081.1 - 2.4 7.8 6.5 3.9 7.1 4.4 1.5 1 1 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family DUF342 PF03961.8 CDI86081.1 - 2.8 6.2 10.0 3.3 6.0 6.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF4175 PF13779.1 CDI86081.1 - 2.8 5.5 28.7 3.2 5.3 19.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Neur_chan_memb PF02932.11 CDI86081.1 - 3.2 7.5 13.1 4.2 7.1 9.1 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF4407 PF14362.1 CDI86081.1 - 3.3 6.5 14.9 4.4 6.1 10.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Lipoprotein_10 PF03202.8 CDI86081.1 - 3.3 7.7 15.4 5.1 7.1 10.6 1.4 1 1 0 1 1 1 0 Putative mycoplasma lipoprotein, C-terminal region DUF3523 PF12037.3 CDI86081.1 - 3.4 6.5 24.2 4.6 6.1 16.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3523) Plasmodium_Vir PF05795.6 CDI86081.1 - 3.9 6.5 8.4 4.8 6.2 5.8 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Herpes_UL87 PF03043.9 CDI86081.1 - 4 5.7 10.5 4.7 5.4 7.3 1.0 1 0 0 1 1 1 0 Herpesvirus UL87 family Med15 PF09606.5 CDI86081.1 - 5.2 5.1 40.9 6.1 4.8 28.4 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF4613 PF15390.1 CDI86081.1 - 7.6 4.5 14.9 9.1 4.3 10.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) ZYG-11_interact PF05884.7 CDI86081.1 - 8 5.4 13.5 9.9 5.1 9.3 1.1 1 0 0 1 1 1 0 Interactor of ZYG-11 SRP-alpha_N PF04086.8 CDI86081.1 - 8.4 5.6 18.2 10 5.3 12.6 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal AAA_11 PF13086.1 CDI86082.1 - 0.0021 17.6 8.3 0.0023 17.5 5.8 1.2 1 0 0 1 1 1 1 AAA domain DUF4386 PF14329.1 CDI86082.1 - 0.0024 17.4 4.0 0.0031 17.0 2.8 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4386) IncA PF04156.9 CDI86082.1 - 0.012 15.2 5.3 0.012 15.2 3.7 3.1 3 0 0 3 3 3 0 IncA protein DELLA PF12041.3 CDI86082.1 - 0.018 14.6 0.6 0.045 13.4 0.4 1.7 1 0 0 1 1 1 0 Transcriptional regulator DELLA protein N terminal IPK PF03770.11 CDI86082.1 - 0.16 11.6 16.0 0.2 11.2 11.1 1.4 1 1 0 1 1 1 0 Inositol polyphosphate kinase ERG2_Sigma1R PF04622.7 CDI86082.1 - 0.38 9.9 2.2 0.55 9.4 1.6 1.3 1 0 0 1 1 1 0 ERG2 and Sigma1 receptor like protein GET2 PF08690.5 CDI86082.1 - 0.88 8.7 19.4 1.3 8.2 13.4 1.3 1 0 0 1 1 1 0 GET complex subunit GET2 BcsB PF03170.8 CDI86082.1 - 1.1 7.1 18.1 1.5 6.7 12.6 1.1 1 0 0 1 1 1 0 Bacterial cellulose synthase subunit KilA-N PF04383.8 CDI86082.1 - 2 8.0 9.4 3 7.5 6.5 1.4 1 0 0 1 1 1 0 KilA-N domain Band_3_cyto PF07565.8 CDI86082.1 - 2 7.8 17.2 3.2 7.1 11.9 1.3 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Peptidase_S46 PF10459.4 CDI86082.1 - 2.9 6.1 25.1 3.7 5.8 17.4 1.1 1 0 0 1 1 1 0 Peptidase S46 FLO_LFY PF01698.11 CDI86082.1 - 6.6 5.4 16.5 10 4.8 11.5 1.2 1 0 0 1 1 1 0 Floricaula / Leafy protein DUF2407 PF10302.4 CDI86082.1 - 9.5 6.4 11.1 2.7 8.2 5.3 1.8 2 1 0 2 2 2 0 DUF2407 ubiquitin-like domain Plasmodium_Vir PF05795.6 CDI86083.1 - 0.023 13.9 12.0 0.026 13.7 8.3 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Shisa PF13908.1 CDI86083.1 - 0.089 12.9 0.5 0.11 12.6 0.3 1.3 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Kei1 PF08552.6 CDI86083.1 - 0.13 11.9 5.9 0.097 12.3 3.2 1.5 1 1 1 2 2 2 0 Inositolphosphorylceramide synthase subunit Kei1 Nucleoside_tran PF01733.13 CDI86083.1 - 0.37 9.8 4.6 0.39 9.8 3.2 1.0 1 0 0 1 1 1 0 Nucleoside transporter APC_CDC26 PF10471.4 CDI86083.1 - 0.44 11.3 12.6 0.1 13.3 4.1 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit 1 DUF912 PF06024.7 CDI86083.1 - 0.6 10.2 8.2 0.11 12.5 2.2 1.9 1 1 1 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Mucin PF01456.12 CDI86083.1 - 0.98 9.1 13.2 1.1 9.0 9.2 1.1 1 0 0 1 1 1 0 Mucin-like glycoprotein PAP1 PF08601.5 CDI86083.1 - 1.4 8.5 17.3 1.5 8.4 12.0 1.0 1 0 0 1 1 1 0 Transcription factor PAP1 Z1 PF10593.4 CDI86083.1 - 1.5 7.9 5.9 1.7 7.8 4.1 1.0 1 0 0 1 1 1 0 Z1 domain Ctr PF04145.10 CDI86083.1 - 1.6 8.7 4.3 2.2 8.2 3.0 1.4 1 1 0 1 1 1 0 Ctr copper transporter family Vma12 PF11712.3 CDI86083.1 - 2.5 7.8 5.7 2.8 7.6 3.9 1.3 1 1 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase PEHE PF15275.1 CDI86083.1 - 6.8 7.1 9.9 8.7 6.8 6.8 1.2 1 1 0 1 1 1 0 PEHE domain DUF605 PF04652.11 CDI86083.1 - 8.2 5.7 10.9 10 5.4 7.6 1.1 1 0 0 1 1 1 0 Vta1 like NfeD PF01957.13 CDI86084.1 - 0.034 14.2 3.0 0.068 13.2 1.2 2.2 2 0 0 2 2 2 0 NfeD-like C-terminal, partner-binding LMBR1 PF04791.11 CDI86084.1 - 0.18 10.3 3.7 0.055 12.0 0.4 1.9 1 1 0 2 2 2 0 LMBR1-like membrane protein Dicty_REP PF05086.7 CDI86084.1 - 1.2 6.8 10.1 1.6 6.3 7.0 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Amidohydro_2 PF04909.9 CDI86085.1 - 2.6 7.5 7.1 4.1 6.8 4.9 1.4 1 0 0 1 1 1 0 Amidohydrolase DOR PF14839.1 CDI86085.1 - 6.3 6.4 18.7 17 5.0 12.9 1.8 1 1 0 1 1 1 0 DOR family Suf PF05843.9 CDI86086.1 - 8.8e-05 22.3 18.0 0.0051 16.5 2.2 2.2 2 0 0 2 2 2 2 Suppressor of forked protein (Suf) zf-DHHC PF01529.15 CDI86086.1 - 0.00016 21.1 0.6 0.49 9.7 0.1 2.7 2 0 0 2 2 2 2 DHHC palmitoyltransferase Med15 PF09606.5 CDI86086.1 - 0.00045 18.5 61.6 0.023 12.9 20.5 2.4 2 0 0 2 2 2 2 ARC105 or Med15 subunit of Mediator complex non-fungal FimP PF09766.4 CDI86086.1 - 0.0028 16.8 31.8 0.0089 15.1 6.4 2.1 2 0 0 2 2 2 2 Fms-interacting protein Spt20 PF12090.3 CDI86086.1 - 0.01 15.2 19.1 0.063 12.6 2.6 2.3 2 0 0 2 2 2 0 Spt20 family TFIIA PF03153.8 CDI86086.1 - 0.017 15.0 34.3 0.17 11.7 10.6 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit FLO_LFY PF01698.11 CDI86086.1 - 0.031 13.1 15.9 0.12 11.2 3.8 2.2 2 0 0 2 2 2 0 Floricaula / Leafy protein Band_3_cyto PF07565.8 CDI86086.1 - 0.096 12.1 20.4 0.092 12.2 4.8 2.2 2 0 0 2 2 2 0 Band 3 cytoplasmic domain PAT1 PF09770.4 CDI86086.1 - 0.11 10.7 39.5 0.35 9.0 10.7 2.2 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 Plasmodium_Vir PF05795.6 CDI86086.1 - 0.12 11.6 6.9 1.7 7.7 0.4 2.1 2 0 0 2 2 2 0 Plasmodium vivax Vir protein SAGA-Tad1 PF12767.2 CDI86086.1 - 0.12 12.0 18.9 0.27 10.8 3.4 2.2 2 0 0 2 2 2 0 Transcriptional regulator of RNA polII, SAGA, subunit DUF2052 PF09747.4 CDI86086.1 - 0.14 12.0 23.0 0.59 10.0 3.4 2.3 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) Pex14_N PF04695.8 CDI86086.1 - 0.23 11.5 26.5 0.027 14.5 1.3 3.0 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF4557 PF15101.1 CDI86086.1 - 0.39 10.5 32.0 1.8 8.3 7.7 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4557) Gti1_Pac2 PF09729.4 CDI86086.1 - 0.46 10.3 11.2 1.2 9.0 0.8 2.2 2 0 0 2 2 2 0 Gti1/Pac2 family DDHD PF02862.12 CDI86086.1 - 0.97 9.1 18.1 3 7.5 1.8 2.3 2 0 0 2 2 2 0 DDHD domain Spore_coat_CotO PF14153.1 CDI86086.1 - 0.99 8.8 30.2 2.2 7.7 5.7 2.3 2 0 0 2 2 2 0 Spore coat protein CotO Peptidase_C58 PF03543.9 CDI86086.1 - 1.1 8.6 21.9 0.33 10.4 3.8 2.4 2 0 0 2 2 2 0 Yersinia/Haemophilus virulence surface antigen Herpes_UL87 PF03043.9 CDI86086.1 - 1.1 7.5 3.4 1.7 6.9 2.4 1.3 1 0 0 1 1 1 0 Herpesvirus UL87 family Vfa1 PF08432.5 CDI86086.1 - 1.3 8.9 24.1 1 9.3 7.9 2.3 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 Ycf1 PF05758.7 CDI86086.1 - 1.4 6.5 14.7 0.28 8.8 1.9 2.0 2 0 0 2 2 2 0 Ycf1 Dynamin_N PF00350.18 CDI86086.1 - 2 8.1 8.0 9.9 5.9 1.7 2.3 2 0 0 2 2 2 0 Dynamin family CDC45 PF02724.9 CDI86086.1 - 2.3 6.1 16.3 1.5 6.7 4.0 2.1 2 0 0 2 2 2 0 CDC45-like protein DUF3801 PF12687.2 CDI86086.1 - 2.3 7.7 22.9 0.26 10.8 3.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3801) DUF2722 PF10846.3 CDI86086.1 - 2.8 6.8 25.8 3.2 6.6 6.8 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) DUF4011 PF13195.1 CDI86086.1 - 3.1 7.7 13.4 3.7 7.5 3.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4011) DUF1764 PF08576.5 CDI86086.1 - 4.4 8.1 25.5 11 6.8 5.7 2.6 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF1764) Auxin_inducible PF02519.9 CDI86086.1 - 4.5 7.3 11.1 2.1 8.4 1.1 2.5 2 0 0 2 2 2 0 Auxin responsive protein UPF0560 PF10577.4 CDI86086.1 - 4.7 5.3 27.9 0.38 8.9 5.4 2.1 2 0 0 2 2 2 0 Uncharacterised protein family UPF0560 CPSF100_C PF13299.1 CDI86086.1 - 5 7.2 16.7 4.6 7.3 1.3 2.4 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal PRP3 PF08572.5 CDI86086.1 - 6 6.1 25.9 4.4 6.6 4.6 2.2 2 0 0 2 2 2 0 pre-mRNA processing factor 3 (PRP3) DUF1510 PF07423.6 CDI86086.1 - 6.8 5.9 26.6 1.8 7.9 7.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) TMEM51 PF15345.1 CDI86086.1 - 7 6.2 22.6 9.5 5.8 5.0 2.5 2 0 0 2 2 2 0 Transmembrane protein 51 Ank_5 PF13857.1 CDI86087.1 - 1.4e-18 66.5 0.1 1e-11 44.6 0.0 3.0 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.25 CDI86087.1 - 4.1e-17 61.0 0.2 1.1e-08 34.4 0.1 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.2 CDI86087.1 - 1.2e-16 60.8 0.1 2.4e-16 59.8 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 CDI86087.1 - 8.4e-16 58.0 0.0 1.3e-10 41.5 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 CDI86087.1 - 6.8e-11 41.3 0.1 0.00055 19.9 0.0 2.9 3 0 0 3 3 3 2 Ankyrin repeat ACBP PF00887.14 CDI86087.1 - 0.00063 19.3 0.1 0.0012 18.5 0.1 1.4 1 0 0 1 1 1 1 Acyl CoA binding protein FERM_M PF00373.13 CDI86087.1 - 0.074 13.2 0.1 0.15 12.2 0.1 1.5 1 0 0 1 1 1 0 FERM central domain Neur_chan_memb PF02932.11 CDI86088.1 - 0.12 12.1 0.4 0.73 9.6 0.0 2.3 2 1 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region OmpH PF03938.9 CDI86089.1 - 5.6e-06 26.3 1.5 5.6e-06 26.3 1.1 3.3 1 1 1 2 2 2 1 Outer membrane protein (OmpH-like) DUF3037 PF11236.3 CDI86089.1 - 0.028 14.4 0.2 0.14 12.2 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3037) RTBV_P46 PF06216.6 CDI86089.1 - 0.66 8.7 0.8 1 8.1 0.6 1.2 1 0 0 1 1 1 0 Rice tungro bacilliform virus P46 protein TPPK_C PF12555.3 CDI86090.1 - 0.72 9.6 0.0 0.72 9.6 0.0 3.0 3 0 0 3 3 3 0 Thiamine pyrophosphokinase C terminal ATP_bind_4 PF01902.12 CDI86092.1 - 8.3e-32 110.3 0.0 2.4e-31 108.8 0.0 1.7 1 1 0 1 1 1 1 ATP-binding region AAA PF00004.24 CDI86093.1 - 9.8e-39 132.5 0.0 1.9e-38 131.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.5 CDI86093.1 - 2.8e-21 75.1 0.2 6.3e-21 74.0 0.1 1.6 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain RuvB_N PF05496.7 CDI86093.1 - 6.6e-05 22.0 0.1 0.00022 20.3 0.0 1.8 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 CDI86093.1 - 9.8e-05 23.1 0.0 0.00028 21.6 0.0 1.8 1 1 0 1 1 1 1 AAA domain MIT PF04212.13 CDI86093.1 - 0.0001 22.0 0.1 0.14 12.0 0.0 2.8 2 0 0 2 2 2 2 MIT (microtubule interacting and transport) domain AAA_25 PF13481.1 CDI86093.1 - 0.00013 21.4 0.7 0.63 9.4 0.2 2.9 2 1 1 3 3 3 2 AAA domain IstB_IS21 PF01695.12 CDI86093.1 - 0.00026 20.4 0.0 0.0005 19.5 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_22 PF13401.1 CDI86093.1 - 0.0007 19.7 0.0 0.036 14.1 0.0 2.6 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 CDI86093.1 - 0.0039 17.0 0.0 0.0079 16.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.9 CDI86093.1 - 0.005 16.7 0.0 0.009 15.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.1 CDI86093.1 - 0.011 15.5 0.1 0.066 13.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.1 CDI86093.1 - 0.017 15.1 0.0 3.7 7.5 0.0 2.8 1 1 1 2 2 2 0 AAA ATPase domain AAA_5 PF07728.9 CDI86093.1 - 0.031 13.9 1.0 0.13 12.0 0.1 2.5 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 CDI86093.1 - 0.1 12.3 0.0 0.27 10.9 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain DnaJ PF00226.26 CDI86094.1 - 1.6e-21 75.8 0.4 3.3e-21 74.7 0.3 1.5 1 0 0 1 1 1 1 DnaJ domain DUF1014 PF06244.7 CDI86095.1 - 7.3e-22 77.8 15.9 4.3e-20 72.1 11.0 2.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1014) HMG_box PF00505.14 CDI86095.1 - 0.039 14.2 0.1 0.039 14.2 0.1 2.5 2 1 0 2 2 2 0 HMG (high mobility group) box DUF2951 PF11166.3 CDI86095.1 - 0.83 9.5 5.6 2.3 8.1 3.9 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2951) TSC22 PF01166.13 CDI86096.1 - 0.064 13.2 6.7 0.03 14.2 1.3 2.7 2 0 0 2 2 2 0 TSC-22/dip/bun family DUF972 PF06156.8 CDI86096.1 - 0.33 11.3 17.5 0.047 14.0 2.5 3.7 1 1 2 3 3 3 0 Protein of unknown function (DUF972) Seryl_tRNA_N PF02403.17 CDI86096.1 - 1.1 9.3 17.3 6 6.9 7.4 2.8 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain CCDC-167 PF15188.1 CDI86096.1 - 4.8 7.1 12.1 0.58 10.1 4.9 2.2 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 Kinetocho_Slk19 PF12709.2 CDI86096.1 - 5 7.2 11.2 14 5.8 2.6 3.2 2 1 2 4 4 4 0 Central kinetochore-associated DUF4201 PF13870.1 CDI86096.1 - 5.1 6.4 21.7 1.5 8.2 9.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4201) V_ATPase_I PF01496.14 CDI86096.1 - 5.5 4.7 10.3 8.2 4.1 7.1 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Prominin PF05478.6 CDI86096.1 - 5.6 4.3 7.9 8.6 3.7 5.4 1.3 1 0 0 1 1 1 0 Prominin CENP-F_leu_zip PF10473.4 CDI86096.1 - 9.4 6.0 33.6 0.93 9.3 3.3 3.6 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 FYDLN_acid PF09538.5 CDI86097.1 - 0.86 10.2 11.3 0.82 10.2 1.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) Herpes_UL87 PF03043.9 CDI86097.1 - 7.2 4.8 22.5 8.7 4.5 15.6 1.1 1 0 0 1 1 1 0 Herpesvirus UL87 family PAT1 PF09770.4 CDI86097.1 - 7.9 4.5 76.8 9.9 4.2 53.2 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TFIIA PF03153.8 CDI86099.1 - 0.28 11.0 8.2 0.4 10.5 5.7 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4207 PF13904.1 CDI86100.1 - 0.0063 15.9 12.4 0.0063 15.9 8.6 3.5 2 1 0 2 2 2 1 Domain of unknown function (DUF4207) Herpes_UL87 PF03043.9 CDI86100.1 - 1.3 7.3 11.0 3.6 5.8 7.6 1.7 1 1 0 1 1 1 0 Herpesvirus UL87 family IncA PF04156.9 CDI86101.1 - 6.5e-05 22.6 38.4 6.5e-05 22.6 26.6 2.0 1 1 1 2 2 1 1 IncA protein DUF1510 PF07423.6 CDI86101.1 - 0.17 11.2 31.6 0.22 10.8 21.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) PAT1 PF09770.4 CDI86101.1 - 0.22 9.7 74.9 0.25 9.5 51.9 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Med15 PF09606.5 CDI86101.1 - 0.27 9.3 100.8 0.34 9.0 69.9 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal GAGA_bind PF06217.7 CDI86101.1 - 0.85 9.5 34.2 1 9.2 23.7 1.0 1 0 0 1 1 1 0 GAGA binding protein-like family CAF-1_p150 PF11600.3 CDI86101.1 - 1.1 8.6 45.8 1.3 8.3 31.8 1.0 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF4045 PF13254.1 CDI86101.1 - 1.2 8.2 31.3 1.6 7.9 21.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) AMP-binding PF00501.23 CDI86101.1 - 3.7 5.8 6.8 4.4 5.5 4.7 1.2 1 0 0 1 1 1 0 AMP-binding enzyme SAGA-Tad1 PF12767.2 CDI86101.1 - 4.5 6.8 41.8 5.4 6.6 29.0 1.1 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit FLO_LFY PF01698.11 CDI86101.1 - 5.5 5.7 32.4 7.7 5.2 22.5 1.3 1 0 0 1 1 1 0 Floricaula / Leafy protein PA26 PF04636.8 CDI86101.1 - 6.5 5.3 22.4 7.4 5.1 15.5 1.0 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Paramyxo_ncap PF00973.14 CDI86101.1 - 7.2 5.1 29.6 8.7 4.9 20.5 1.0 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein CDC45 PF02724.9 CDI86101.1 - 9.4 4.1 42.1 12 3.8 29.2 1.0 1 0 0 1 1 1 0 CDC45-like protein LNP1 PF15419.1 CDI86102.1 - 0.98 9.4 21.7 0.82 9.7 0.1 3.3 4 0 0 4 4 4 0 Leukemia NUP98 fusion partner 1 Ribosomal_60s PF00428.14 CDI86103.1 - 0.026 14.9 7.1 0.026 14.9 4.9 1.6 2 0 0 2 2 2 0 60s Acidic ribosomal protein SR-25 PF10500.4 CDI86103.1 - 0.028 13.9 6.6 0.038 13.4 4.6 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Viral_P18 PF04521.8 CDI86103.1 - 0.065 12.6 0.0 0.095 12.1 0.0 1.2 1 0 0 1 1 1 0 ssRNA positive strand viral 18kD cysteine rich protein DUF755 PF05501.6 CDI86103.1 - 1.1 9.3 10.3 1.9 8.5 7.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF755) LEA_3 PF03242.8 CDI86103.1 - 1.7 8.9 7.0 1.6 8.9 0.2 2.1 2 0 0 2 2 2 0 Late embryogenesis abundant protein Corona_nucleoca PF00937.13 CDI86104.1 - 0.001 18.0 6.5 0.0011 18.0 4.5 1.2 1 0 0 1 1 1 1 Coronavirus nucleocapsid protein Ribosomal_60s PF00428.14 CDI86104.1 - 0.037 14.4 19.3 0.26 11.6 13.4 2.3 1 1 0 1 1 1 0 60s Acidic ribosomal protein AstB PF04996.7 CDI86104.1 - 0.043 12.6 3.5 0.053 12.3 2.4 1.1 1 0 0 1 1 1 0 Succinylarginine dihydrolase Rotamase_2 PF13145.1 CDI86104.1 - 0.058 14.0 1.9 0.11 13.1 1.3 1.4 1 0 0 1 1 1 0 PPIC-type PPIASE domain Tim54 PF11711.3 CDI86104.1 - 0.11 11.1 0.1 0.11 11.1 0.0 1.8 1 1 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 TPP_enzyme_N PF02776.13 CDI86104.1 - 0.22 11.0 4.9 0.34 10.3 3.4 1.2 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain DUF3138 PF11336.3 CDI86104.1 - 0.43 8.6 6.0 0.65 8.1 4.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) MIP-T3 PF10243.4 CDI86104.1 - 0.5 8.7 8.5 0.66 8.3 5.9 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 RAP1 PF07218.6 CDI86104.1 - 1.2 7.1 9.9 1.5 6.7 6.9 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Secretin_N_2 PF07655.8 CDI86104.1 - 4.3 7.7 16.0 7.3 7.0 11.1 1.3 1 0 0 1 1 1 0 Secretin N-terminal domain ACDC PF14733.1 CDI86105.1 - 3.1e-11 43.2 0.0 3.1e-11 43.2 0.0 1.8 2 0 0 2 2 2 1 AP2-coincident C-terminal AP2 PF00847.15 CDI86105.1 - 1.6e-09 37.7 1.0 3.1e-06 27.2 0.2 4.5 4 0 0 4 4 4 2 AP2 domain DUF572 PF04502.8 CDI86106.1 - 0.49 9.5 17.7 0.79 8.8 12.3 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF572) zf-DHHC PF01529.15 CDI86106.1 - 2.7 7.3 5.7 6.1 6.2 0.0 2.1 2 0 0 2 2 2 0 DHHC palmitoyltransferase FAM60A PF15396.1 CDI86106.1 - 6.9 6.3 9.2 12 5.5 6.4 1.3 1 0 0 1 1 1 0 Protein Family FAM60A TFIIA PF03153.8 CDI86108.1 - 0.0019 18.1 33.4 0.0019 18.1 23.2 2.5 2 1 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit Peptidase_S64 PF08192.6 CDI86108.1 - 0.59 8.4 15.0 1.4 7.1 10.4 1.6 1 0 0 1 1 1 0 Peptidase family S64 SprA-related PF12118.3 CDI86108.1 - 1.6 8.0 66.6 0.6 9.3 33.6 2.6 2 0 0 2 2 2 0 SprA-related family DUF4220 PF13968.1 CDI86108.1 - 2.3 7.2 8.8 5.1 6.0 6.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4220) Zip PF02535.17 CDI86108.1 - 8.4 5.2 8.7 6.3 5.7 4.3 2.0 2 0 0 2 2 2 0 ZIP Zinc transporter Methyltransf_16 PF10294.4 CDI86109.1 - 5.7e-05 22.6 0.8 0.14 11.6 0.0 3.0 3 1 1 4 4 4 2 Putative methyltransferase DUF912 PF06024.7 CDI86109.1 - 0.031 14.3 0.4 0.059 13.4 0.3 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) FA_desaturase PF00487.19 CDI86109.1 - 0.056 12.8 0.2 0.076 12.4 0.1 1.1 1 0 0 1 1 1 0 Fatty acid desaturase DUF2207 PF09972.4 CDI86109.1 - 0.27 9.7 1.7 0.39 9.2 1.2 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF4191 PF13829.1 CDI86109.1 - 2 7.4 4.6 2.9 6.9 3.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) DUF2101 PF09874.4 CDI86109.1 - 9.7 5.6 12.8 13 5.2 8.9 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2101) Ribosomal_60s PF00428.14 CDI86111.1 - 0.67 10.3 6.0 1 9.8 4.1 1.3 1 0 0 1 1 1 0 60s Acidic ribosomal protein RAP1 PF07218.6 CDI86112.1 - 0.0013 16.9 4.2 0.0013 16.9 2.9 1.0 1 0 0 1 1 1 1 Rhoptry-associated protein 1 (RAP-1) Med15 PF09606.5 CDI86112.1 - 0.22 9.6 24.7 0.3 9.2 17.1 1.3 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Med15 PF09606.5 CDI86113.1 - 0.0021 16.3 77.0 0.0028 15.9 53.4 1.1 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal DUF1180 PF06679.7 CDI86113.1 - 1.2 8.9 3.9 1.9 8.3 2.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Ribosomal_60s PF00428.14 CDI86114.1 - 0.038 14.3 8.0 0.038 14.3 5.5 2.4 2 1 0 2 2 2 0 60s Acidic ribosomal protein Phostensin_N PF13916.1 CDI86114.1 - 0.13 12.2 4.4 0.22 11.5 3.1 1.5 1 0 0 1 1 1 0 PP1-regulatory protein, Phostensin N-terminal dCMP_cyt_deam_1 PF00383.17 CDI86114.1 - 0.24 11.0 3.1 0.33 10.6 2.2 1.2 1 0 0 1 1 1 0 Cytidine and deoxycytidylate deaminase zinc-binding region Pex14_N PF04695.8 CDI86114.1 - 0.24 11.4 11.6 0.31 11.0 8.0 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Hamartin PF04388.7 CDI86114.1 - 0.86 8.1 4.5 0.84 8.2 3.1 1.1 1 0 0 1 1 1 0 Hamartin protein Med15 PF09606.5 CDI86114.1 - 1.2 7.2 25.6 1.4 6.9 17.7 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Cyto_heme_lyase PF01265.12 CDI86114.1 - 2.7 7.4 6.6 3.8 7.0 4.6 1.2 1 0 0 1 1 1 0 Cytochrome c/c1 heme lyase DUF755 PF05501.6 CDI86115.1 - 0.0014 18.6 31.3 0.0014 18.6 21.7 4.0 3 1 1 4 4 4 1 Domain of unknown function (DUF755) BAF1_ABF1 PF04684.8 CDI86115.1 - 0.67 8.7 44.0 0.062 12.1 24.1 2.2 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor FAM60A PF15396.1 CDI86115.1 - 3.6 7.2 31.4 1.3 8.7 13.1 2.3 2 0 0 2 2 2 0 Protein Family FAM60A DUF572 PF04502.8 CDI86115.1 - 7.1 5.7 33.0 0.4 9.8 13.9 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF572) Macoilin PF09726.4 CDI86115.1 - 7.7 4.6 45.3 0.13 10.4 14.1 2.2 2 0 0 2 2 2 0 Transmembrane protein SRP-alpha_N PF04086.8 CDI86116.1 - 6.5 6.0 43.3 7.5 5.8 30.0 1.0 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Pkinase PF00069.20 CDI86117.1 - 3.7e-13 49.2 0.0 9.2e-13 47.9 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Apt1 PF10351.4 CDI86117.1 - 0.14 10.9 5.9 0.17 10.6 4.1 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Pkinase_Tyr PF07714.12 CDI86117.1 - 0.15 11.1 0.0 0.52 9.3 0.0 1.8 2 0 0 2 2 2 0 Protein tyrosine kinase SR-25 PF10500.4 CDI86120.1 - 0.00085 18.8 11.6 0.00085 18.8 8.0 10.1 8 3 1 9 9 9 1 Nuclear RNA-splicing-associated protein Nha1_C PF08619.5 CDI86120.1 - 0.0046 16.2 8.2 0.0046 16.2 5.7 6.0 6 0 0 6 6 6 3 Alkali metal cation/H+ antiporter Nha1 C terminus PAT1 PF09770.4 CDI86120.1 - 0.51 8.5 186.2 0.054 11.7 27.3 5.2 5 0 0 5 5 5 0 Topoisomerase II-associated protein PAT1 IncA PF04156.9 CDI86122.1 - 0.0015 18.1 20.0 0.0018 17.9 13.9 1.0 1 0 0 1 1 1 1 IncA protein FimP PF09766.4 CDI86122.1 - 0.0052 15.8 13.6 0.0055 15.8 9.5 1.1 1 0 0 1 1 1 1 Fms-interacting protein Spt20 PF12090.3 CDI86122.1 - 0.0068 15.7 6.6 0.0083 15.4 4.6 1.3 1 0 0 1 1 1 1 Spt20 family Suf PF05843.9 CDI86122.1 - 0.01 15.6 11.4 0.01 15.5 7.9 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) TraT PF05818.7 CDI86122.1 - 0.016 14.6 15.4 0.02 14.3 10.6 1.1 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein DUF2244 PF10003.4 CDI86122.1 - 0.034 13.5 0.9 0.042 13.2 0.6 1.2 1 0 0 1 1 1 0 Integral membrane protein (DUF2244) DUF2232 PF09991.4 CDI86122.1 - 0.061 12.3 8.5 0.065 12.2 5.9 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) TMEM247 PF15444.1 CDI86122.1 - 0.085 12.6 5.2 0.098 12.4 3.6 1.1 1 0 0 1 1 1 0 Transmembrane protein 247 DNA_ligase_A_M PF01068.16 CDI86122.1 - 0.086 12.1 2.3 0.13 11.5 1.6 1.4 1 1 0 1 1 1 0 ATP dependent DNA ligase domain OATP PF03137.15 CDI86122.1 - 0.094 10.7 4.9 0.096 10.7 3.4 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family ARGLU PF15346.1 CDI86122.1 - 0.13 11.9 18.9 0.17 11.6 13.1 1.1 1 0 0 1 1 1 0 Arginine and glutamate-rich 1 DUF4131 PF13567.1 CDI86122.1 - 0.14 11.5 4.0 0.17 11.3 2.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) Peptidase_S49_N PF08496.5 CDI86122.1 - 0.24 11.1 8.5 0.29 10.8 5.9 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF572 PF04502.8 CDI86122.1 - 0.31 10.2 10.7 0.35 10.0 7.4 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF4207 PF13904.1 CDI86122.1 - 0.41 9.9 20.8 0.47 9.7 14.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4207) Serinc PF03348.10 CDI86122.1 - 0.48 9.0 8.6 0.51 8.9 6.0 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) HA2 PF04408.18 CDI86122.1 - 0.54 10.3 5.5 0.74 9.8 3.8 1.4 1 1 0 1 1 1 0 Helicase associated domain (HA2) CD20 PF04103.10 CDI86122.1 - 0.85 9.5 6.4 1.4 8.8 4.4 1.5 1 1 0 1 1 1 0 CD20-like family TFIIA PF03153.8 CDI86122.1 - 0.96 9.2 27.3 1.1 9.0 18.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit FAM222A PF15258.1 CDI86122.1 - 1.1 8.4 19.5 1.5 7.9 13.5 1.3 1 0 0 1 1 1 0 Protein family of FAM222A eIF-3_zeta PF05091.7 CDI86122.1 - 1.1 7.7 12.1 1.2 7.6 8.4 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF3959 PF13105.1 CDI86122.1 - 1.2 8.4 5.7 1.6 8.0 3.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3959) PAT1 PF09770.4 CDI86122.1 - 1.3 7.1 27.9 1.5 6.9 19.3 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 RAB3GAP2_N PF14655.1 CDI86122.1 - 1.5 7.7 13.8 2.2 7.1 9.6 1.3 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus ATP-grasp PF02222.17 CDI86122.1 - 1.9 7.8 6.8 2.3 7.5 4.7 1.2 1 0 0 1 1 1 0 ATP-grasp domain Peptidase_S15 PF02129.13 CDI86122.1 - 2.5 7.4 13.4 2.9 7.2 9.3 1.2 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Dala_Dala_lig_N PF01820.16 CDI86122.1 - 2.7 8.3 7.8 3.3 8.0 5.2 1.3 1 1 0 1 1 1 0 D-ala D-ala ligase N-terminus DUF912 PF06024.7 CDI86122.1 - 3.1 7.8 9.9 3.2 7.8 6.2 1.6 1 1 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Bac_luciferase PF00296.15 CDI86122.1 - 3.5 6.6 15.4 4.1 6.4 10.7 1.0 1 0 0 1 1 1 0 Luciferase-like monooxygenase ATAD4 PF15321.1 CDI86122.1 - 6.3 7.8 9.5 12 7.0 6.6 1.4 1 0 0 1 1 1 0 ATPase family AAA domain containing 4 Pex16 PF08610.5 CDI86122.1 - 8 5.3 12.2 10 5.0 8.5 1.1 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) Pilt PF15453.1 CDI86122.1 - 8.1 6.0 14.2 9.2 5.8 9.9 1.0 1 0 0 1 1 1 0 Protein incorporated later into Tight Junctions UPF0560 PF10577.4 CDI86122.1 - 8.4 4.5 17.3 8.8 4.4 12.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Claudin_2 PF13903.1 CDI86123.1 - 0.0013 18.4 0.8 0.0013 18.4 0.6 7.0 7 0 0 7 7 7 2 PMP-22/EMP/MP20/Claudin tight junction DUF4414 PF14377.1 CDI86123.1 - 0.04 13.8 0.3 0.04 13.8 0.2 8.7 7 2 0 7 7 7 0 Domain of unknown function (DUF4414) DUF3306 PF11748.3 CDI86123.1 - 0.22 12.1 0.1 0.22 12.1 0.1 10.7 11 2 1 12 12 12 0 Protein of unknown function (DUF3306) RICTOR_N PF14664.1 CDI86124.1 - 0.0069 15.0 0.4 0.0069 15.0 0.3 4.7 4 0 0 4 4 4 3 Rapamycin-insensitive companion of mTOR, N-term HemX PF04375.9 CDI86125.1 - 1.6e-05 23.6 39.1 2e-05 23.4 27.1 1.0 1 0 0 1 1 1 1 HemX Med15 PF09606.5 CDI86125.1 - 0.011 14.0 67.6 0.014 13.6 46.8 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal IncA PF04156.9 CDI86125.1 - 0.014 15.0 37.8 0.068 12.7 26.2 1.9 1 1 0 1 1 1 0 IncA protein DUF342 PF03961.8 CDI86125.1 - 0.047 12.1 13.8 0.054 11.9 9.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) PAT1 PF09770.4 CDI86125.1 - 0.053 11.7 49.3 0.057 11.6 34.2 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Bac_luciferase PF00296.15 CDI86125.1 - 0.071 12.2 6.3 0.12 11.4 4.3 1.4 1 1 0 1 1 1 0 Luciferase-like monooxygenase FAM60A PF15396.1 CDI86125.1 - 0.1 12.3 16.0 0.12 12.1 11.1 1.0 1 0 0 1 1 1 0 Protein Family FAM60A Peptidase_S49_N PF08496.5 CDI86125.1 - 0.11 12.2 16.0 0.13 12.0 11.1 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Exonuc_VII_L PF02601.10 CDI86125.1 - 0.12 11.5 24.9 0.12 11.4 17.2 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit Shadoo PF14999.1 CDI86125.1 - 0.12 12.2 9.7 0.17 11.7 6.7 1.3 1 0 0 1 1 1 0 Shadow of prion protein, neuroprotective DUF2828 PF11443.3 CDI86125.1 - 0.13 10.4 11.0 0.14 10.3 7.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) HAUS6_N PF14661.1 CDI86125.1 - 0.17 11.1 23.6 0.19 11.0 16.3 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus BORG_CEP PF14957.1 CDI86125.1 - 0.46 11.4 13.1 0.52 11.2 9.1 1.2 1 0 0 1 1 1 0 Cdc42 effector DUF2215 PF10225.4 CDI86125.1 - 0.51 9.7 11.1 0.53 9.6 7.7 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) DUF2052 PF09747.4 CDI86125.1 - 0.54 10.1 24.3 0.66 9.8 16.8 1.1 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) DUF1510 PF07423.6 CDI86125.1 - 0.72 9.1 20.4 0.78 9.0 14.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Sporozoite_P67 PF05642.6 CDI86125.1 - 0.74 7.6 8.1 0.84 7.4 5.6 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen SelP_N PF04592.9 CDI86125.1 - 0.84 8.9 20.9 1 8.6 14.5 1.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Herpes_UL87 PF03043.9 CDI86125.1 - 0.9 7.8 10.7 0.96 7.7 7.4 1.0 1 0 0 1 1 1 0 Herpesvirus UL87 family DUF4045 PF13254.1 CDI86125.1 - 0.92 8.7 17.7 0.97 8.6 12.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Gag_spuma PF03276.9 CDI86125.1 - 0.94 7.7 35.5 1.1 7.5 24.6 1.2 1 0 0 1 1 1 0 Spumavirus gag protein SAGA-Tad1 PF12767.2 CDI86125.1 - 1 9.0 23.3 1.1 8.8 16.1 1.1 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit Zip PF02535.17 CDI86125.1 - 1 8.3 10.5 1.2 8.0 7.3 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Peptidase_S15 PF02129.13 CDI86125.1 - 1.2 8.4 18.5 1.4 8.2 12.8 1.1 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) FemAB PF02388.11 CDI86125.1 - 1.3 7.5 24.7 1.7 7.2 17.1 1.1 1 0 0 1 1 1 0 FemAB family eIF-3_zeta PF05091.7 CDI86125.1 - 1.6 7.2 26.4 1.6 7.2 18.3 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) FLO_LFY PF01698.11 CDI86125.1 - 1.6 7.4 19.1 1.9 7.2 13.2 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein DDHD PF02862.12 CDI86125.1 - 1.6 8.4 18.6 1.9 8.2 12.9 1.1 1 0 0 1 1 1 0 DDHD domain RR_TM4-6 PF06459.7 CDI86125.1 - 2 8.2 18.8 2.1 8.1 13.0 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 TFIIA PF03153.8 CDI86125.1 - 2.3 7.9 40.4 3 7.6 28.0 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit BTV_NS2 PF04514.7 CDI86125.1 - 2.4 6.9 16.5 2.7 6.8 11.4 1.0 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Mnd1 PF03962.10 CDI86125.1 - 2.6 7.6 29.3 3.2 7.3 20.3 1.1 1 0 0 1 1 1 0 Mnd1 family MRP-S31 PF15433.1 CDI86125.1 - 2.7 7.3 26.7 3.3 7.0 18.5 1.0 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 DUF3450 PF11932.3 CDI86125.1 - 3.2 6.9 43.0 4.3 6.5 29.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Cellulose_synt PF03552.9 CDI86125.1 - 3.6 5.7 10.0 3.7 5.7 6.9 1.0 1 0 0 1 1 1 0 Cellulose synthase Muted PF14942.1 CDI86125.1 - 4 7.3 24.5 5 6.9 17.0 1.1 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein Tim54 PF11711.3 CDI86125.1 - 4.3 5.8 13.6 5.2 5.5 9.5 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 AUX_IAA PF02309.11 CDI86125.1 - 4.6 6.9 18.7 4.9 6.8 12.9 1.1 1 0 0 1 1 1 0 AUX/IAA family Baculo_PP31 PF05311.6 CDI86125.1 - 4.7 6.3 18.7 6.4 5.9 13.0 1.3 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) Med19 PF10278.4 CDI86125.1 - 6.9 6.3 15.9 8.5 6.0 11.0 1.1 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 Rtf2 PF04641.7 CDI86125.1 - 7.3 5.7 22.1 9.8 5.2 15.3 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger UPF0560 PF10577.4 CDI86125.1 - 7.4 4.6 33.5 10 4.2 23.2 1.3 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 DUF2126 PF09899.4 CDI86125.1 - 9.8 4.0 14.8 11 3.9 10.3 1.1 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) zf-C2HC5 PF06221.8 CDI86126.1 - 0.0099 15.6 8.3 1 9.1 5.7 3.2 1 1 0 1 1 1 1 Putative zinc finger motif, C2HC5-type DUF4657 PF15552.1 CDI86127.1 - 0.064 12.5 10.2 0.022 14.0 3.5 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4657) V-SNARE PF05008.10 CDI86127.1 - 0.11 12.6 0.2 3.4 7.8 0.0 2.3 2 0 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus WBP-1 PF11669.3 CDI86129.1 - 0.034 14.2 0.2 0.036 14.1 0.1 1.2 1 0 0 1 1 1 0 WW domain-binding protein 1 Baculo_11_kDa PF06143.6 CDI86129.1 - 0.035 13.4 1.5 0.047 13.0 1.1 1.2 1 0 0 1 1 1 0 Baculovirus 11 kDa family TMEM154 PF15102.1 CDI86129.1 - 0.049 13.3 0.7 0.058 13.1 0.5 1.2 1 0 0 1 1 1 0 TMEM154 protein family Tmemb_9 PF05434.6 CDI86129.1 - 0.053 13.2 0.4 0.064 12.9 0.3 1.2 1 0 0 1 1 1 0 TMEM9 IncA PF04156.9 CDI86130.1 - 8e-06 25.5 25.4 8e-06 25.5 17.6 1.6 1 1 0 1 1 1 1 IncA protein SAPS PF04499.10 CDI86130.1 - 0.0034 16.0 16.4 0.0033 16.1 11.4 1.3 1 0 0 1 1 1 1 SIT4 phosphatase-associated protein eIF-3_zeta PF05091.7 CDI86130.1 - 0.0042 15.7 26.0 0.0051 15.4 18.0 1.3 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) BTV_NS2 PF04514.7 CDI86130.1 - 0.0053 15.6 15.8 0.0061 15.4 10.9 1.1 1 0 0 1 1 1 1 Bluetongue virus non-structural protein NS2 Utp14 PF04615.8 CDI86130.1 - 0.0076 14.4 31.0 0.0082 14.3 21.5 1.2 1 0 0 1 1 1 1 Utp14 protein Tetraspannin PF00335.15 CDI86130.1 - 0.012 14.9 4.6 0.015 14.6 3.2 1.2 1 0 0 1 1 1 0 Tetraspanin family DUF1510 PF07423.6 CDI86130.1 - 0.022 14.1 30.1 0.032 13.6 20.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Hid1 PF12722.2 CDI86130.1 - 0.17 9.5 32.9 0.21 9.2 22.8 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Bud13 PF09736.4 CDI86130.1 - 0.17 12.1 28.6 0.032 14.4 17.5 1.6 2 0 0 2 2 1 0 Pre-mRNA-splicing factor of RES complex Ycf1 PF05758.7 CDI86130.1 - 0.18 9.5 23.5 0.21 9.2 16.3 1.0 1 0 0 1 1 1 0 Ycf1 PPP4R2 PF09184.6 CDI86130.1 - 0.18 11.3 18.2 0.26 10.8 12.6 1.4 1 0 0 1 1 1 0 PPP4R2 GAGA_bind PF06217.7 CDI86130.1 - 0.19 11.6 25.8 0.29 11.0 17.9 1.4 1 0 0 1 1 1 0 GAGA binding protein-like family SAGA-Tad1 PF12767.2 CDI86130.1 - 0.35 10.5 27.4 0.46 10.1 19.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit DUF342 PF03961.8 CDI86130.1 - 0.37 9.1 12.5 0.42 8.9 8.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Raftlin PF15250.1 CDI86130.1 - 0.46 8.9 22.0 0.58 8.6 15.2 1.3 1 0 0 1 1 1 0 Raftlin Med15 PF09606.5 CDI86130.1 - 0.58 8.2 82.6 0.84 7.7 57.3 1.3 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal TT_ORF1 PF02956.9 CDI86130.1 - 0.87 7.9 22.8 1 7.7 15.8 1.1 1 0 0 1 1 1 0 TT viral orf 1 Ndc1_Nup PF09531.5 CDI86130.1 - 0.89 7.9 24.9 1 7.6 17.3 1.4 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DDRGK PF09756.4 CDI86130.1 - 1 8.7 34.2 1.6 8.0 23.7 1.3 1 0 0 1 1 1 0 DDRGK domain DUF1168 PF06658.7 CDI86130.1 - 1.1 8.7 35.0 0.17 11.3 21.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1168) PAT1 PF09770.4 CDI86130.1 - 1.6 6.8 64.7 2 6.5 44.9 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Nucleoside_tran PF01733.13 CDI86130.1 - 2.3 7.2 11.8 4.2 6.4 8.2 1.5 1 1 0 1 1 1 0 Nucleoside transporter Cellulose_synt PF03552.9 CDI86130.1 - 3 6.0 12.6 3.8 5.7 8.7 1.1 1 0 0 1 1 1 0 Cellulose synthase Plasmodium_Vir PF05795.6 CDI86130.1 - 5.1 6.1 20.6 7.3 5.6 14.3 1.5 1 1 0 1 1 1 0 Plasmodium vivax Vir protein Parvo_coat PF00740.13 CDI86130.1 - 5.2 5.8 35.1 6.1 5.6 24.3 1.1 1 0 0 1 1 1 0 Parvovirus coat protein VP2 Mnd1 PF03962.10 CDI86130.1 - 6.1 6.4 30.8 9.2 5.8 21.3 1.2 1 0 0 1 1 1 0 Mnd1 family SOBP PF15279.1 CDI86130.1 - 6.3 7.0 33.6 8.4 6.6 23.3 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein DUF3584 PF12128.3 CDI86130.1 - 9 3.4 47.0 11 3.1 32.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) RRM_1 PF00076.17 CDI86133.1 - 5.7e-16 57.9 0.0 9.1e-16 57.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CDI86133.1 - 1.2e-14 54.0 0.0 1.9e-14 53.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CDI86133.1 - 3.2e-09 36.5 0.2 5.2e-09 35.8 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SPOC PF07744.8 CDI86133.1 - 4.3e-06 27.1 0.0 1.1e-05 25.8 0.0 1.7 1 0 0 1 1 1 1 SPOC domain BRAP2 PF07576.7 CDI86133.1 - 0.034 13.7 0.0 0.059 12.9 0.0 1.3 1 0 0 1 1 1 0 BRCA1-associated protein 2 SET_assoc PF11767.3 CDI86133.1 - 0.16 11.2 0.1 0.27 10.5 0.1 1.3 1 0 0 1 1 1 0 Histone lysine methyltransferase SET associated Methyltransf_11 PF08241.7 CDI86134.1 - 3.7e-12 46.5 0.0 3.6e-11 43.3 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CDI86134.1 - 9.5e-07 29.1 0.1 3.1e-06 27.4 0.1 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CDI86134.1 - 1.6e-06 27.9 0.0 4e-06 26.6 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CDI86134.1 - 4.3e-06 27.1 0.2 3e-05 24.4 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 CDI86134.1 - 5.1e-05 22.8 0.0 0.00015 21.4 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CDI86134.1 - 0.00023 21.7 0.2 0.0024 18.4 0.2 2.3 1 1 0 1 1 1 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.12 CDI86134.1 - 0.052 12.5 0.0 0.1 11.5 0.0 1.4 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family DUF1962 PF09227.5 CDI86134.1 - 0.053 13.5 0.9 0.13 12.3 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1962) Methyltransf_9 PF08003.6 CDI86134.1 - 0.24 10.0 1.9 0.28 9.8 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1698) UPF0560 PF10577.4 CDI86134.1 - 0.61 8.2 6.3 0.83 7.8 4.4 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 eIF-3_zeta PF05091.7 CDI86134.1 - 0.85 8.1 8.5 1.3 7.5 5.9 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Glyco_transf_92 PF01697.22 CDI86134.1 - 0.95 8.7 4.1 1.6 7.9 2.9 1.3 1 0 0 1 1 1 0 Glycosyltransferase family 92 FimP PF09766.4 CDI86134.1 - 8.5 5.3 13.8 12 4.7 9.6 1.1 1 0 0 1 1 1 0 Fms-interacting protein DUF3458 PF11940.3 CDI86135.1 - 8.2e-116 386.8 0.6 1.2e-115 386.2 0.4 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3458) Peptidase_M1 PF01433.15 CDI86135.1 - 1.4e-55 189.0 0.0 2e-55 188.5 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M1 zf-DNL PF05180.7 CDI86135.1 - 2.1e-27 94.5 0.5 4e-27 93.7 0.3 1.5 1 0 0 1 1 1 1 DNL zinc finger Peptidase_MA_2 PF13485.1 CDI86135.1 - 2.3e-12 47.0 0.1 6e-12 45.7 0.0 1.7 1 0 0 1 1 1 1 Peptidase MA superfamily DRMBL PF07522.9 CDI86135.1 - 0.0015 18.5 1.2 0.0041 17.1 0.8 1.6 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.2 CDI86135.1 - 0.01 15.3 0.0 0.051 13.1 0.0 2.1 2 0 0 2 2 2 0 Beta-lactamase superfamily domain RMMBL PF07521.7 CDI86135.1 - 0.011 15.5 0.2 0.024 14.4 0.1 1.6 1 0 0 1 1 1 0 RNA-metabolising metallo-beta-lactamase MSP1_C PF07462.6 CDI86135.1 - 4.7 5.4 4.5 9 4.5 3.1 1.4 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus cNMP_binding PF00027.24 CDI86137.1 - 1.4e-12 47.2 0.0 2.3e-06 27.3 0.0 3.0 1 1 1 2 2 2 2 Cyclic nucleotide-binding domain ClpS PF02617.12 CDI86138.1 - 3e-16 58.8 0.3 3e-16 58.8 0.2 1.5 2 0 0 2 2 2 1 ATP-dependent Clp protease adaptor protein ClpS DUF3826 PF12875.2 CDI86138.1 - 0.052 13.2 0.4 0.067 12.8 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3826) Cupin_1 PF00190.17 CDI86138.1 - 0.052 12.9 0.0 0.078 12.4 0.0 1.4 1 0 0 1 1 1 0 Cupin Pterin_bind PF00809.17 CDI86139.1 - 8.2e-67 224.6 0.0 1.3e-66 223.9 0.0 1.4 1 0 0 1 1 1 1 Pterin binding enzyme HPPK PF01288.15 CDI86139.1 - 2e-22 79.3 0.0 4.6e-22 78.1 0.0 1.7 1 0 0 1 1 1 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) tRNA-synt_1 PF00133.17 CDI86140.1 - 3.6e-08 31.8 0.0 4.7e-08 31.5 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) FUSC PF04632.7 CDI86140.1 - 0.0069 14.8 9.3 0.0093 14.4 6.5 1.1 1 0 0 1 1 1 1 Fusaric acid resistance protein family HdeA PF06411.6 CDI86140.1 - 4.9 7.1 7.0 20 5.2 4.9 2.0 1 1 0 1 1 1 0 HdeA/HdeB family CD20 PF04103.10 CDI86142.1 - 3.9 7.4 9.6 9.2 6.1 6.7 1.7 1 1 0 1 1 1 0 CD20-like family MMR_HSR1 PF01926.18 CDI86143.1 - 1.3e-10 41.2 0.0 2e-10 40.6 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 CDI86143.1 - 2e-07 30.4 0.1 6.4e-06 25.5 0.0 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B ATP_bind_1 PF03029.12 CDI86143.1 - 0.0039 16.7 0.3 0.74 9.3 0.0 2.2 2 0 0 2 2 2 2 Conserved hypothetical ATP binding protein AAA_16 PF13191.1 CDI86143.1 - 0.0039 17.1 0.0 0.0069 16.3 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain Dynamin_N PF00350.18 CDI86143.1 - 0.027 14.2 0.1 0.042 13.6 0.1 1.5 1 1 0 1 1 1 0 Dynamin family AAA_33 PF13671.1 CDI86143.1 - 0.028 14.2 1.4 0.063 13.1 1.0 1.6 1 1 0 1 1 1 0 AAA domain GTP_EFTU PF00009.22 CDI86143.1 - 0.081 12.3 0.0 1.4 8.2 0.0 2.2 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Miro PF08477.8 CDI86143.1 - 0.14 12.6 0.4 3.6 8.1 0.3 2.5 1 1 0 1 1 1 0 Miro-like protein Myc_N PF01056.13 CDI86143.1 - 0.16 11.0 0.8 0.2 10.8 0.5 1.1 1 0 0 1 1 1 0 Myc amino-terminal region TH1 PF04858.8 CDI86143.1 - 0.26 9.3 1.7 0.32 9.0 1.1 1.0 1 0 0 1 1 1 0 TH1 protein DUF3138 PF11336.3 CDI86143.1 - 0.28 9.2 6.0 0.36 8.9 4.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) AAA_28 PF13521.1 CDI86143.1 - 1.5 8.7 4.0 2.9 7.8 0.7 2.1 2 0 0 2 2 2 0 AAA domain Cut8_M PF14483.1 CDI86144.1 - 0.098 12.4 0.9 0.38 10.5 0.4 2.2 3 0 0 3 3 3 0 Cut8 dimerisation domain DUF508 PF04370.7 CDI86144.1 - 2.3 7.8 5.8 3.8 7.1 4.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF508) Ribosomal_60s PF00428.14 CDI86144.1 - 4.5 7.7 21.4 3.8 7.9 2.3 2.7 2 0 0 2 2 2 0 60s Acidic ribosomal protein TPPII_N PF12583.3 CDI86144.1 - 5.5 7.1 12.1 0.94 9.6 4.6 2.0 2 0 0 2 2 2 0 Tripeptidyl peptidase II N terminal Gly-zipper_OmpA PF13436.1 CDI86144.1 - 8 6.1 16.0 20 4.8 6.8 2.4 2 0 0 2 2 2 0 Glycine-zipper containing OmpA-like membrane domain Lipoprotein_21 PF14041.1 CDI86145.1 - 0.013 15.4 0.0 2.9 7.8 0.0 2.3 2 0 0 2 2 2 0 LppP/LprE lipoprotein Spatacsin_C PF14649.1 CDI86145.1 - 0.13 11.1 0.0 12 4.7 0.0 2.2 2 0 0 2 2 2 0 Spatacsin C-terminus CAF-1_p150 PF11600.3 CDI86146.1 - 0.013 14.8 9.7 0.018 14.4 6.7 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal SOBP PF15279.1 CDI86146.1 - 0.027 14.8 10.4 0.034 14.5 7.2 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein Activator_LAG-3 PF11498.3 CDI86146.1 - 0.036 12.8 24.8 0.051 12.3 17.2 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Suf PF05843.9 CDI86146.1 - 0.068 12.8 10.4 0.096 12.3 7.2 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) CDK5_activator PF03261.10 CDI86146.1 - 0.07 12.4 11.2 0.091 12.0 7.7 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein NMDAR2_C PF10565.4 CDI86146.1 - 0.078 11.6 8.9 0.1 11.2 6.2 1.1 1 0 0 1 1 1 0 N-methyl D-aspartate receptor 2B3 C-terminus Spt20 PF12090.3 CDI86146.1 - 0.088 12.1 4.2 0.12 11.7 2.9 1.3 1 0 0 1 1 1 0 Spt20 family DUF912 PF06024.7 CDI86146.1 - 0.17 11.9 3.5 0.24 11.4 2.0 1.6 1 1 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) FimP PF09766.4 CDI86146.1 - 0.24 10.4 12.3 0.3 10.0 8.5 1.1 1 0 0 1 1 1 0 Fms-interacting protein DUF775 PF05603.7 CDI86146.1 - 0.37 10.2 7.9 0.57 9.6 5.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF775) PAXIP1_C PF15364.1 CDI86146.1 - 0.55 10.1 7.5 0.85 9.5 5.2 1.2 1 0 0 1 1 1 0 PAXIP1-associated-protein-1 C term PTIP binding protein DUF4557 PF15101.1 CDI86146.1 - 0.59 9.9 12.2 0.9 9.3 8.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) CD20 PF04103.10 CDI86146.1 - 0.91 9.4 9.0 1.5 8.7 4.5 2.5 1 1 0 1 1 1 0 CD20-like family Corona_nucleoca PF00937.13 CDI86146.1 - 2.1 7.2 13.6 3 6.6 9.5 1.2 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein SR-25 PF10500.4 CDI86146.1 - 2.2 7.6 19.5 4.8 6.5 13.5 1.6 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein FLO_LFY PF01698.11 CDI86146.1 - 10 4.8 10.1 15 4.2 7.0 1.2 1 0 0 1 1 1 0 Floricaula / Leafy protein Ribosomal_60s PF00428.14 CDI86147.1 - 4.7 7.6 13.9 8.1 6.9 3.0 2.2 2 0 0 2 2 2 0 60s Acidic ribosomal protein Shadoo PF14999.1 CDI86148.1 - 0.011 15.6 6.4 0.011 15.6 4.4 6.7 2 2 2 5 5 5 0 Shadow of prion protein, neuroprotective TSC22 PF01166.13 CDI86148.1 - 0.15 12.0 5.8 20 5.2 0.0 3.7 3 0 0 3 3 3 0 TSC-22/dip/bun family FlxA PF14282.1 CDI86148.1 - 0.55 10.2 24.9 0.13 12.1 4.5 4.0 2 1 1 3 3 3 0 FlxA-like protein Herpes_BLRF2 PF05812.7 CDI86148.1 - 3 7.6 10.0 0.67 9.7 2.3 3.1 2 2 0 2 2 2 0 Herpesvirus BLRF2 protein FH2 PF02181.18 CDI86148.1 - 4.1 6.1 11.1 0.13 11.0 0.3 2.5 3 0 0 3 3 3 0 Formin Homology 2 Domain DUF812 PF05667.6 CDI86150.1 - 0.011 14.2 23.5 0.013 14.0 16.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Halo_GVPC PF05465.8 CDI86150.1 - 0.7 9.8 8.0 5.5 7.0 1.4 2.8 1 1 1 2 2 2 0 Halobacterial gas vesicle protein C (GVPC) repeat IncA PF04156.9 CDI86150.1 - 0.86 9.1 18.9 0.93 9.0 13.1 1.0 1 0 0 1 1 1 0 IncA protein Atg14 PF10186.4 CDI86150.1 - 3.3 6.5 9.4 3.6 6.4 6.5 1.0 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Fmp27_WPPW PF10359.4 CDI86150.1 - 6.3 5.0 13.9 6.9 4.9 9.7 1.0 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Lipoprotein_2 PF00921.12 CDI86151.1 - 0.0021 18.1 13.7 0.0022 18.0 9.5 1.0 1 0 0 1 1 1 1 Borrelia lipoprotein Glt_symporter PF03616.9 CDI86151.1 - 0.09 11.2 3.1 0.092 11.2 2.2 1.0 1 0 0 1 1 1 0 Sodium/glutamate symporter Med15 PF09606.5 CDI86151.1 - 0.15 10.2 41.4 0.15 10.2 28.7 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal RskA PF10099.4 CDI86151.1 - 0.17 11.5 9.8 0.21 11.2 6.8 1.1 1 0 0 1 1 1 0 Anti-sigma-K factor rskA VIT1 PF01988.14 CDI86151.1 - 0.56 9.6 3.9 0.6 9.5 2.7 1.1 1 0 0 1 1 1 0 VIT family DUF2950 PF11453.3 CDI86151.1 - 0.94 8.4 11.8 1 8.3 8.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2950) DUF2453 PF10507.4 CDI86151.1 - 1.4 8.7 3.9 1.6 8.5 2.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2453) FimP PF09766.4 CDI86151.1 - 1.6 7.7 17.9 1.5 7.8 12.4 1.0 1 0 0 1 1 1 0 Fms-interacting protein FLO_LFY PF01698.11 CDI86151.1 - 3 6.5 10.4 3.1 6.5 7.2 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein AAA_23 PF13476.1 CDI86151.1 - 3.2 8.0 11.0 2.8 8.2 7.6 1.1 1 0 0 1 1 1 0 AAA domain Pex14_N PF04695.8 CDI86151.1 - 3.4 7.7 17.4 3.9 7.5 12.1 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF4175 PF13779.1 CDI86151.1 - 5.8 4.4 28.0 5.5 4.5 19.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) DUF4557 PF15101.1 CDI86151.1 - 5.8 6.6 20.9 6.3 6.5 14.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) MelC1 PF06236.6 CDI86151.1 - 7 6.6 10.0 8.2 6.4 7.0 1.1 1 0 0 1 1 1 0 Tyrosinase co-factor MelC1 DUF1980 PF09323.5 CDI86151.1 - 7.3 6.2 7.3 7 6.3 5.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) R_equi_Vir PF05526.6 CDI86151.1 - 8.8 5.9 8.9 9.4 5.8 6.2 1.0 1 0 0 1 1 1 0 Rhodococcus equi virulence-associated protein Gag_spuma PF03276.9 CDI86151.1 - 9.4 4.4 23.0 9.6 4.3 15.9 1.0 1 0 0 1 1 1 0 Spumavirus gag protein Tetraspannin PF00335.15 CDI86153.1 - 0.0036 16.6 2.7 0.0046 16.2 1.9 1.1 1 0 0 1 1 1 1 Tetraspanin family Ashwin PF15323.1 CDI86153.1 - 0.057 13.4 4.5 0.065 13.2 3.1 1.1 1 0 0 1 1 1 0 Developmental protein MIP-T3 PF10243.4 CDI86153.1 - 0.083 11.3 9.9 0.1 11.0 6.9 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DUF2477 PF10631.4 CDI86153.1 - 0.29 11.3 14.7 0.17 12.0 9.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2477) Pex14_N PF04695.8 CDI86153.1 - 0.7 9.9 11.1 0.24 11.4 5.6 1.7 1 1 1 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF4401 PF14351.1 CDI86153.1 - 0.84 8.5 9.2 2.5 7.0 6.3 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4401) DUF755 PF05501.6 CDI86153.1 - 4.5 7.3 29.3 2.5 8.1 18.5 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF755) Macoilin PF09726.4 CDI86153.1 - 7.9 4.6 16.5 9 4.4 11.4 1.1 1 0 0 1 1 1 0 Transmembrane protein DUF3357 PF11837.3 CDI86154.1 - 2 8.2 11.7 0.16 11.8 1.0 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF3357) Usp PF00582.21 CDI86154.1 - 8.9 6.5 5.9 3.7 7.7 0.2 2.7 3 0 0 3 3 3 0 Universal stress protein family DUF4184 PF13803.1 CDI86155.1 - 0.095 11.9 1.8 0.32 10.2 0.3 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4184) BRF1 PF07741.8 CDI86155.1 - 5.3 7.3 8.8 1.5 9.0 1.2 2.6 2 1 0 2 2 2 0 Brf1-like TBP-binding domain SR-25 PF10500.4 CDI86156.1 - 0.0081 15.6 22.4 0.0081 15.6 15.5 2.4 2 1 0 2 2 2 1 Nuclear RNA-splicing-associated protein Transferase PF02458.10 CDI86156.1 - 0.082 11.3 3.8 0.1 11.0 2.7 1.2 1 0 0 1 1 1 0 Transferase family CDC45 PF02724.9 CDI86156.1 - 0.33 8.9 20.2 0.045 11.7 8.5 2.1 2 0 0 2 2 2 0 CDC45-like protein Hid1 PF12722.2 CDI86156.1 - 0.48 8.0 19.9 0.0088 13.7 7.0 1.9 2 0 0 2 2 2 0 High-temperature-induced dauer-formation protein CAF-1_p150 PF11600.3 CDI86156.1 - 0.87 8.9 35.0 1.6 8.0 2.1 2.1 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Spc7_N PF15402.1 CDI86156.1 - 1.1 7.2 26.1 0.022 12.8 10.9 2.1 2 0 0 2 2 2 0 N-terminus of kinetochore NMS complex subunit Spc7 DUF3337 PF11816.3 CDI86156.1 - 2.7 7.3 12.9 0.14 11.5 3.9 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3337) Raftlin PF15250.1 CDI86156.1 - 3.1 6.2 17.8 1.7 7.0 8.3 2.0 2 0 0 2 2 2 0 Raftlin AAA_11 PF13086.1 CDI86156.1 - 3.7 7.0 23.6 1.1 8.7 10.1 2.1 2 0 0 2 2 2 0 AAA domain DUF4228 PF14009.1 CDI86156.1 - 6 6.9 33.4 4.9 7.2 5.7 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4228) DUF3492 PF11997.3 CDI86156.1 - 6.1 6.2 17.8 0.055 13.0 5.5 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF3492) FimP PF09766.4 CDI86157.1 - 0.0063 15.6 9.8 0.0063 15.6 6.8 5.5 5 1 0 5 5 5 3 Fms-interacting protein IncA PF04156.9 CDI86157.1 - 0.0091 15.6 10.3 0.0091 15.6 7.1 6.0 6 1 0 6 6 6 1 IncA protein Secretin_N_2 PF07655.8 CDI86158.1 - 0.018 15.4 9.3 0.018 15.4 6.5 3.0 3 0 0 3 3 3 0 Secretin N-terminal domain MRP-S26 PF14943.1 CDI86158.1 - 1.7 8.1 8.4 3.4 7.1 5.8 1.4 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 DUF4407 PF14362.1 CDI86158.1 - 1.9 7.3 8.7 2.8 6.8 6.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) V_ATPase_I PF01496.14 CDI86158.1 - 3.8 5.2 4.7 4.7 4.9 3.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DNA_pol_viral_N PF00242.12 CDI86158.1 - 6.1 5.7 18.2 4.8 6.1 4.2 2.1 2 0 0 2 2 2 0 DNA polymerase (viral) N-terminal domain MelC1 PF06236.6 CDI86159.1 - 0.14 12.1 0.1 0.14 12.1 0.1 7.7 4 3 2 6 6 6 0 Tyrosinase co-factor MelC1 MGC-24 PF05283.6 CDI86160.1 - 0.069 12.9 9.4 0.082 12.6 6.5 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24) DUF1754 PF08555.5 CDI86160.1 - 3 8.4 35.1 2.7 8.6 18.0 2.1 2 0 0 2 2 2 0 Eukaryotic family of unknown function (DUF1754) Caldesmon PF02029.10 CDI86160.1 - 6 5.1 31.7 7.1 4.9 22.0 1.0 1 0 0 1 1 1 0 Caldesmon CoA_transf_3 PF02515.12 CDI86161.1 - 0.0056 15.9 8.2 0.0056 15.9 5.7 2.1 2 0 0 2 2 2 1 CoA-transferase family III SOBP PF15279.1 CDI86161.1 - 0.0098 16.3 25.2 0.012 16.0 17.5 1.2 1 0 0 1 1 1 1 Sine oculis-binding protein CAF-1_p150 PF11600.3 CDI86161.1 - 0.021 14.2 39.3 0.032 13.6 27.2 1.3 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Med15 PF09606.5 CDI86161.1 - 0.022 12.9 59.7 0.026 12.7 41.4 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal NMDAR2_C PF10565.4 CDI86161.1 - 0.88 8.1 24.6 1.2 7.7 17.0 1.3 1 0 0 1 1 1 0 N-methyl D-aspartate receptor 2B3 C-terminus GAGA_bind PF06217.7 CDI86161.1 - 1.8 8.4 26.4 2.2 8.1 18.3 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family RAP1 PF07218.6 CDI86161.1 - 2.8 5.9 15.4 3.3 5.7 10.7 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) AAA_23 PF13476.1 CDI86161.1 - 3.6 7.8 27.9 4.8 7.4 19.3 1.2 1 0 0 1 1 1 0 AAA domain Ycf1 PF05758.7 CDI86161.1 - 9.2 3.8 22.8 11 3.6 15.8 1.1 1 0 0 1 1 1 0 Ycf1 APG6 PF04111.7 CDI86161.1 - 9.2 5.2 32.9 11 4.8 22.8 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Nop14 PF04147.7 CDI86162.1 - 0.00017 19.6 28.9 0.00022 19.3 20.0 1.2 1 0 0 1 1 1 1 Nop14-like family Daxx PF03344.10 CDI86162.1 - 0.01 14.3 27.1 0.012 14.1 18.8 1.1 1 0 0 1 1 1 0 Daxx Family Mitofilin PF09731.4 CDI86162.1 - 0.052 12.2 21.2 0.06 12.0 14.7 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Hid1 PF12722.2 CDI86162.1 - 0.28 8.8 17.2 0.33 8.5 11.9 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Borrelia_P83 PF05262.6 CDI86162.1 - 0.34 9.1 23.3 0.38 8.9 16.1 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein CENP-T PF15511.1 CDI86162.1 - 0.34 10.1 28.6 0.48 9.6 19.8 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Ndc1_Nup PF09531.5 CDI86162.1 - 1 7.7 6.9 1.4 7.2 4.8 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Peptidase_S64 PF08192.6 CDI86162.1 - 2.3 6.4 14.1 2.9 6.1 9.8 1.1 1 0 0 1 1 1 0 Peptidase family S64 Macoilin PF09726.4 CDI86162.1 - 3.1 5.9 17.9 4.2 5.5 12.4 1.2 1 0 0 1 1 1 0 Transmembrane protein MIP-T3 PF10243.4 CDI86162.1 - 6 5.2 42.7 8.3 4.7 29.6 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 WxL PF13731.1 CDI86164.1 - 0.11 12.2 3.3 6.1 6.5 0.1 2.2 1 1 1 2 2 2 0 WxL domain surface cell wall-binding ChW PF07538.6 CDI86164.1 - 1.3 8.6 11.2 3.7 7.1 0.4 3.3 3 0 0 3 3 3 0 Clostridial hydrophobic W CDC45 PF02724.9 CDI86165.1 - 1.3 6.9 33.0 1.4 6.9 22.9 1.0 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.7 CDI86165.1 - 1.7 6.4 36.0 1.7 6.4 24.9 1.0 1 0 0 1 1 1 0 Nop14-like family Pox_RNA_Pol_19 PF05320.7 CDI86165.1 - 2.9 7.6 21.8 3.3 7.4 15.1 1.1 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit Pex14_N PF04695.8 CDI86165.1 - 3.1 7.8 8.7 3.3 7.7 6.1 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF2890 PF11081.3 CDI86165.1 - 3.2 7.7 26.4 3.4 7.6 18.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) DUF1510 PF07423.6 CDI86168.1 - 3.7e-08 33.0 10.8 3.8e-08 32.9 7.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) SpoIIIAH PF12685.2 CDI86168.1 - 4.4e-07 29.6 4.9 5.3e-07 29.3 3.4 1.1 1 0 0 1 1 1 1 SpoIIIAH-like protein Neur_chan_memb PF02932.11 CDI86168.1 - 7.3e-05 22.7 10.4 9.1e-05 22.4 7.2 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region DUF1183 PF06682.7 CDI86168.1 - 0.00012 21.8 6.6 0.00013 21.7 4.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1183) TRAP_alpha PF03896.11 CDI86168.1 - 0.00025 20.1 3.1 0.00029 19.9 2.1 1.1 1 0 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit NicO PF03824.11 CDI86168.1 - 0.00053 19.3 7.7 0.00057 19.2 5.3 1.1 1 0 0 1 1 1 1 High-affinity nickel-transport protein DUF4512 PF14975.1 CDI86168.1 - 0.0018 19.0 5.0 0.0027 18.5 3.5 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4512) DUF4446 PF14584.1 CDI86168.1 - 0.002 17.9 12.4 0.0025 17.6 8.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4446) Serinc PF03348.10 CDI86168.1 - 0.0021 16.8 11.1 0.0027 16.4 7.7 1.3 1 0 0 1 1 1 1 Serine incorporator (Serinc) Peptidase_S49_N PF08496.5 CDI86168.1 - 0.0021 17.8 16.5 0.0023 17.7 11.4 1.1 1 0 0 1 1 1 1 Peptidase family S49 N-terminal YfhO PF09586.5 CDI86168.1 - 0.0023 16.0 10.2 0.0032 15.5 7.1 1.3 1 0 0 1 1 1 1 Bacterial membrane protein YfhO SID-1_RNA_chan PF13965.1 CDI86168.1 - 0.0025 16.0 11.7 0.0026 16.0 8.1 1.0 1 0 0 1 1 1 1 dsRNA-gated channel SID-1 Ycf1 PF05758.7 CDI86168.1 - 0.0042 14.8 18.8 0.0043 14.8 13.1 1.0 1 0 0 1 1 1 1 Ycf1 Ni_hydr_CYTB PF01292.15 CDI86168.1 - 0.005 16.2 0.6 0.0074 15.6 0.4 1.3 1 0 0 1 1 1 1 Prokaryotic cytochrome b561 Tetraspannin PF00335.15 CDI86168.1 - 0.0066 15.7 11.5 0.0087 15.3 8.0 1.3 1 1 0 1 1 1 1 Tetraspanin family DUF4175 PF13779.1 CDI86168.1 - 0.0068 14.1 52.5 0.0072 14.0 36.4 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4175) Choline_transpo PF04515.7 CDI86168.1 - 0.007 15.1 0.1 0.0084 14.8 0.1 1.3 1 1 0 1 1 1 1 Plasma-membrane choline transporter DUF3260 PF11658.3 CDI86168.1 - 0.0077 14.4 16.8 0.0084 14.3 11.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3260) Mem_trans PF03547.13 CDI86168.1 - 0.0097 14.2 10.2 0.011 14.0 7.1 1.0 1 0 0 1 1 1 1 Membrane transport protein Neur PF00064.13 CDI86168.1 - 0.0098 14.0 6.6 0.012 13.7 4.5 1.1 1 0 0 1 1 1 1 Neuraminidase Shisa PF13908.1 CDI86168.1 - 0.011 15.9 13.9 0.016 15.4 9.6 1.3 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator FHIPEP PF00771.15 CDI86168.1 - 0.03 12.6 13.0 0.04 12.2 9.0 1.2 1 0 0 1 1 1 0 FHIPEP family RIC3 PF15361.1 CDI86168.1 - 0.031 14.5 18.3 0.04 14.1 12.7 1.2 1 0 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 HemY_N PF07219.8 CDI86168.1 - 0.039 13.5 4.4 0.056 13.0 3.1 1.3 1 1 0 1 1 1 0 HemY protein N-terminus PRA1 PF03208.14 CDI86168.1 - 0.043 13.1 0.1 0.06 12.6 0.1 1.3 1 0 0 1 1 1 0 PRA1 family protein DUF4330 PF14221.1 CDI86168.1 - 0.061 13.1 0.2 0.069 13.0 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4330) Tmemb_9 PF05434.6 CDI86168.1 - 0.073 12.8 21.3 0.085 12.5 14.7 1.2 1 0 0 1 1 1 0 TMEM9 Ion_trans PF00520.26 CDI86168.1 - 0.075 12.2 0.0 0.075 12.2 0.0 1.1 1 0 0 1 1 1 0 Ion transport protein FAM176 PF14851.1 CDI86168.1 - 0.077 12.6 16.5 0.35 10.5 11.4 1.8 1 1 0 1 1 1 0 FAM176 family Gastrin PF00918.12 CDI86168.1 - 0.1 13.3 27.3 0.14 12.9 18.9 1.3 1 0 0 1 1 1 0 Gastrin/cholecystokinin family DUF3139 PF11337.3 CDI86168.1 - 0.12 12.6 7.8 0.063 13.5 3.9 1.8 1 1 1 2 2 1 0 Protein of unknown function (DUF3139) UPF0118 PF01594.11 CDI86168.1 - 0.12 11.2 5.0 0.13 11.2 3.5 1.1 1 0 0 1 1 1 0 Domain of unknown function DUF20 Pex24p PF06398.6 CDI86168.1 - 0.13 11.0 6.2 0.31 9.7 4.3 1.6 1 1 0 1 1 1 0 Integral peroxisomal membrane peroxin OAD_gamma PF04277.8 CDI86168.1 - 0.13 12.6 3.4 0.51 10.7 2.4 1.9 1 1 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain SDF PF00375.13 CDI86168.1 - 0.14 10.8 0.6 0.15 10.8 0.4 1.3 1 1 0 1 1 1 0 Sodium:dicarboxylate symporter family Cytochrom_B_N PF00033.14 CDI86168.1 - 0.16 11.3 7.1 0.39 10.0 4.9 1.7 1 1 0 1 1 1 0 Cytochrome b(N-terminal)/b6/petB Ctr PF04145.10 CDI86168.1 - 0.16 11.9 16.1 0.8 9.7 11.2 1.8 1 1 0 1 1 1 0 Ctr copper transporter family IncA PF04156.9 CDI86168.1 - 0.19 11.3 42.2 0.31 10.6 29.2 1.4 1 1 0 1 1 1 0 IncA protein DUF1632 PF07857.7 CDI86168.1 - 0.19 10.9 2.5 0.22 10.7 1.7 1.2 1 0 0 1 1 1 0 CEO family (DUF1632) CLN3 PF02487.12 CDI86168.1 - 0.2 10.4 6.3 0.23 10.1 4.3 1.2 1 0 0 1 1 1 0 CLN3 protein ABC2_membrane_2 PF12679.2 CDI86168.1 - 0.2 10.4 9.8 0.14 11.0 5.8 1.3 1 1 0 1 1 1 0 ABC-2 family transporter protein Myc_target_1 PF15179.1 CDI86168.1 - 0.23 11.0 6.5 0.37 10.3 4.5 1.4 1 1 0 1 1 1 0 Myc target protein 1 YjgP_YjgQ PF03739.9 CDI86168.1 - 0.26 9.9 8.8 0.44 9.2 6.1 1.4 1 1 0 1 1 1 0 Predicted permease YjgP/YjgQ family RBP_receptor PF14752.1 CDI86168.1 - 0.35 9.1 11.0 0.4 8.9 7.6 1.2 1 0 0 1 1 1 0 Retinol binding protein receptor Tmp39 PF10271.4 CDI86168.1 - 0.39 9.3 11.4 0.42 9.2 7.9 1.1 1 0 0 1 1 1 0 Putative transmembrane protein TCP PF03634.8 CDI86168.1 - 0.4 11.0 22.8 0.47 10.8 15.8 1.1 1 0 0 1 1 1 0 TCP family transcription factor FliP PF00813.15 CDI86168.1 - 0.48 10.1 11.8 0.54 9.9 8.2 1.1 1 0 0 1 1 1 0 FliP family Herpes_glycop PF01528.11 CDI86168.1 - 0.48 9.0 13.2 1.5 7.4 9.1 1.7 1 1 0 1 1 1 0 Herpesvirus glycoprotein M Patched PF02460.13 CDI86168.1 - 0.63 7.8 4.7 0.71 7.7 3.3 1.1 1 0 0 1 1 1 0 Patched family DUF4097 PF13349.1 CDI86168.1 - 0.67 9.4 2.2 1.8 8.0 1.6 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4097) BatD PF13584.1 CDI86168.1 - 0.71 8.3 16.8 0.0078 14.8 5.7 1.8 1 1 1 2 2 1 0 Oxygen tolerance DUF3357 PF11837.3 CDI86168.1 - 0.74 9.6 19.4 76 3.2 13.5 2.7 1 1 0 1 1 1 0 Domain of unknown function (DUF3357) Chordopox_A33R PF05966.7 CDI86168.1 - 0.84 8.3 12.9 1.6 7.4 8.6 1.7 1 1 0 1 1 1 0 Chordopoxvirus A33R protein DUF4320 PF14208.1 CDI86168.1 - 0.93 9.4 7.7 1.2 9.0 5.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4320) Reticulon PF02453.12 CDI86168.1 - 0.97 9.0 4.7 1.5 8.3 3.2 1.5 1 1 0 1 1 1 0 Reticulon DUF2140 PF09911.4 CDI86168.1 - 1.1 8.3 15.9 0.25 10.4 8.4 1.7 1 1 1 2 2 1 0 Uncharacterized protein conserved in bacteria (DUF2140) DUF2232 PF09991.4 CDI86168.1 - 1.2 8.0 13.7 0.062 12.2 5.9 1.5 1 1 1 2 2 2 0 Predicted membrane protein (DUF2232) ATP-synt_8 PF00895.15 CDI86168.1 - 1.3 9.2 7.5 6 7.1 5.2 2.2 1 1 0 1 1 1 0 ATP synthase protein 8 K_trans PF02705.11 CDI86168.1 - 1.3 7.2 8.8 1.7 6.9 6.1 1.1 1 0 0 1 1 1 0 K+ potassium transporter DUF843 PF05814.6 CDI86168.1 - 1.5 8.6 7.7 2.6 7.8 5.3 1.7 1 1 0 1 1 1 0 Baculovirus protein of unknown function (DUF843) Sre PF03125.13 CDI86168.1 - 1.5 7.6 5.8 1.9 7.3 4.0 1.1 1 0 0 1 1 1 0 C. elegans Sre G protein-coupled chemoreceptor PIG-P PF08510.7 CDI86168.1 - 1.7 8.3 9.8 8.7 5.9 6.8 1.9 1 1 0 1 1 1 0 PIG-P Kei1 PF08552.6 CDI86168.1 - 1.8 8.1 15.7 3.2 7.3 10.9 1.5 1 1 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 Cellulose_synt PF03552.9 CDI86168.1 - 2 6.6 7.5 2 6.6 5.2 1.2 1 0 0 1 1 1 0 Cellulose synthase Folate_carrier PF01770.13 CDI86168.1 - 2.2 6.7 16.5 3.4 6.0 11.4 1.4 1 1 0 1 1 1 0 Reduced folate carrier Nucleoside_tran PF01733.13 CDI86168.1 - 2.3 7.3 9.9 3.2 6.8 6.8 1.3 1 1 0 1 1 1 0 Nucleoside transporter DUF2215 PF10225.4 CDI86168.1 - 2.5 7.4 13.2 3.4 7.0 9.1 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) ODV-E18 PF10717.4 CDI86168.1 - 2.5 7.6 6.1 2.1 7.8 3.2 1.7 1 1 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 Herpes_DNAp_acc PF04929.7 CDI86168.1 - 2.5 6.9 18.3 2.8 6.7 12.7 1.0 1 0 0 1 1 1 0 Herpes DNA replication accessory factor GRP PF07172.6 CDI86168.1 - 2.7 8.5 17.8 16 6.0 12.3 2.1 1 1 0 1 1 1 0 Glycine rich protein family HCO3_cotransp PF00955.16 CDI86168.1 - 3.1 6.3 8.6 3.2 6.2 6.0 1.0 1 0 0 1 1 1 0 HCO3- transporter family YABBY PF04690.8 CDI86168.1 - 4.2 7.5 17.2 4.8 7.3 11.9 1.2 1 0 0 1 1 1 0 YABBY protein OATP PF03137.15 CDI86168.1 - 4.5 5.1 20.4 0.028 12.4 7.6 1.7 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family FAM163 PF15069.1 CDI86168.1 - 4.7 7.7 7.1 5.6 7.5 4.9 1.2 1 0 0 1 1 1 0 FAM163 family MMR1 PF08505.5 CDI86168.1 - 4.7 7.1 26.8 4.8 7.1 18.6 1.1 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein TadE PF07811.7 CDI86168.1 - 4.9 7.1 7.4 8.8 6.3 5.1 1.4 1 0 0 1 1 1 0 TadE-like protein DUF3169 PF11368.3 CDI86168.1 - 5.6 6.0 7.7 0.82 8.8 2.6 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3169) DUF3365 PF11845.3 CDI86168.1 - 7.4 6.3 18.8 12 5.6 13.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3365) DUF2370 PF10176.4 CDI86168.1 - 7.9 5.7 15.6 10 5.3 10.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) MLANA PF14991.1 CDI86168.1 - 8.9 6.3 8.4 23 5.0 5.8 1.8 1 1 0 1 1 1 0 Protein melan-A RskA PF10099.4 CDI86168.1 - 9.7 5.8 16.2 39 3.9 11.2 2.0 1 1 0 1 1 1 0 Anti-sigma-K factor rskA DUF605 PF04652.11 CDI86170.1 - 0.59 9.4 49.5 0.91 8.8 34.3 1.3 1 0 0 1 1 1 0 Vta1 like CRT10 PF08728.5 CDI86171.1 - 0.12 10.3 2.9 0.13 10.2 2.0 1.1 1 0 0 1 1 1 0 CRT10 SprA-related PF12118.3 CDI86172.1 - 0.0014 18.0 17.6 0.0018 17.6 12.2 1.1 1 0 0 1 1 1 1 SprA-related family NAM-associated PF14303.1 CDI86172.1 - 0.0041 17.4 5.6 0.0053 17.0 3.9 1.1 1 0 0 1 1 1 1 No apical meristem-associated C-terminal domain DUF4207 PF13904.1 CDI86172.1 - 0.021 14.1 19.4 0.033 13.5 13.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4207) FLO_LFY PF01698.11 CDI86172.1 - 0.03 13.1 6.2 0.036 12.9 4.3 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein DUF1501 PF07394.7 CDI86172.1 - 0.078 11.7 6.7 0.086 11.6 4.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) PAT1 PF09770.4 CDI86172.1 - 0.082 11.1 17.1 0.097 10.9 11.8 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 CDK5_activator PF03261.10 CDI86172.1 - 0.1 11.9 13.1 0.12 11.7 9.1 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein PAS_4 PF08448.5 CDI86172.1 - 0.11 12.5 0.2 0.14 12.2 0.1 1.1 1 0 0 1 1 1 0 PAS fold SAGA-Tad1 PF12767.2 CDI86172.1 - 0.12 12.0 13.3 0.14 11.7 9.2 1.1 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit DUF4614 PF15391.1 CDI86172.1 - 0.12 12.1 15.4 0.16 11.7 10.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) CAF-1_p150 PF11600.3 CDI86172.1 - 0.13 11.5 19.7 0.17 11.2 13.7 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF3801 PF12687.2 CDI86172.1 - 0.14 11.7 9.4 0.18 11.3 6.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3801) Suf PF05843.9 CDI86172.1 - 0.16 11.6 13.4 0.2 11.3 9.3 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF605 PF04652.11 CDI86172.1 - 0.21 10.9 16.1 0.27 10.6 11.2 1.1 1 0 0 1 1 1 0 Vta1 like Serinc PF03348.10 CDI86172.1 - 0.29 9.7 9.3 0.35 9.5 6.4 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) TFIIA PF03153.8 CDI86172.1 - 0.51 10.1 16.6 0.59 9.9 11.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Senescence_reg PF04520.8 CDI86172.1 - 0.61 10.5 7.7 0.91 10.0 5.3 1.2 1 0 0 1 1 1 0 Senescence regulator Apt1 PF10351.4 CDI86172.1 - 0.96 8.2 10.3 1.3 7.8 7.1 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Cellulose_synt PF03552.9 CDI86172.1 - 1 7.5 5.0 1.2 7.3 3.4 1.0 1 0 0 1 1 1 0 Cellulose synthase AAA_23 PF13476.1 CDI86172.1 - 1.2 9.3 7.2 1.6 8.9 5.0 1.2 1 0 0 1 1 1 0 AAA domain Peptidase_S64 PF08192.6 CDI86172.1 - 1.4 7.1 12.9 1.6 6.9 9.0 1.0 1 0 0 1 1 1 0 Peptidase family S64 Corona_nucleoca PF00937.13 CDI86172.1 - 2 7.3 21.5 2.7 6.8 14.9 1.1 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein ATG16 PF08614.6 CDI86172.1 - 2 8.2 18.2 2.6 7.8 12.6 1.1 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) IncA PF04156.9 CDI86172.1 - 2.5 7.6 16.0 3.1 7.3 11.1 1.1 1 0 0 1 1 1 0 IncA protein DUF2860 PF11059.3 CDI86172.1 - 4.6 6.2 12.1 0.78 8.7 3.9 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2860) RAB3GAP2_N PF14655.1 CDI86172.1 - 5.3 5.9 15.5 3.4 6.5 6.0 2.0 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus DUF3474 PF11960.3 CDI86172.1 - 8 6.4 9.1 26 4.8 6.3 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF3474) DUF4175 PF13779.1 CDI86172.1 - 9.7 3.7 21.8 13 3.3 15.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) CAF-1_p150 PF11600.3 CDI86173.1 - 0.00082 18.8 83.6 0.0064 15.8 43.2 2.3 2 0 0 2 2 2 2 Chromatin assembly factor 1 complex p150 subunit, N-terminal PAT1 PF09770.4 CDI86173.1 - 0.24 9.5 98.3 0.29 9.3 68.1 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 ATG22 PF11700.3 CDI86174.1 - 0.00013 20.6 1.7 0.00015 20.4 1.2 1.1 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like DUF1212 PF06738.7 CDI86174.1 - 0.0018 17.7 1.6 0.0027 17.1 1.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1212) Anoctamin PF04547.7 CDI86174.1 - 0.016 13.8 1.0 0.019 13.6 0.7 1.1 1 0 0 1 1 1 0 Calcium-activated chloride channel CALCOCO1 PF07888.6 CDI86174.1 - 0.044 12.0 9.9 0.054 11.7 6.8 1.1 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like AAA_11 PF13086.1 CDI86174.1 - 0.084 12.4 8.8 0.11 12.0 6.1 1.2 1 0 0 1 1 1 0 AAA domain DLH PF01738.13 CDI86174.1 - 0.14 11.4 4.5 0.19 10.9 3.1 1.4 1 1 0 1 1 1 0 Dienelactone hydrolase family Peptidase_C58 PF03543.9 CDI86174.1 - 0.14 11.6 10.8 0.18 11.2 7.5 1.2 1 0 0 1 1 1 0 Yersinia/Haemophilus virulence surface antigen DUF3512 PF12024.3 CDI86174.1 - 0.3 10.3 5.1 0.43 9.8 3.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3512) Suf PF05843.9 CDI86174.1 - 0.51 10.0 6.3 0.6 9.7 4.4 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) RED_N PF07808.8 CDI86174.1 - 0.57 9.3 9.7 0.88 8.7 6.3 1.7 2 0 0 2 2 2 0 RED-like protein N-terminal region DUF1266 PF06889.6 CDI86174.1 - 0.59 9.9 5.6 0.9 9.3 3.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1266) HlyD_2 PF12700.2 CDI86174.1 - 0.6 9.2 4.3 0.55 9.3 3.0 1.1 1 0 0 1 1 1 0 HlyD family secretion protein Ycf1 PF05758.7 CDI86174.1 - 0.81 7.3 3.7 0.77 7.3 2.6 1.0 1 0 0 1 1 1 0 Ycf1 DUF912 PF06024.7 CDI86174.1 - 1 9.4 4.4 1.6 8.8 1.5 2.0 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) FimP PF09766.4 CDI86174.1 - 2.5 7.0 15.4 3.6 6.5 10.7 1.1 1 0 0 1 1 1 0 Fms-interacting protein PAT1 PF09770.4 CDI86174.1 - 4.7 5.3 17.1 5.6 5.0 11.9 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TMEM51 PF15345.1 CDI86174.1 - 6.6 6.3 8.4 11 5.6 5.8 1.4 1 0 0 1 1 1 0 Transmembrane protein 51 UPF0560 PF10577.4 CDI86174.1 - 6.9 4.7 9.6 8.5 4.4 6.7 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Med15 PF09606.5 CDI86174.1 - 9.5 4.2 30.4 14 3.7 21.1 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF912 PF06024.7 CDI86175.1 - 0.0029 17.6 0.3 0.0029 17.6 0.2 2.8 3 0 0 3 3 3 1 Nucleopolyhedrovirus protein of unknown function (DUF912) BUD22 PF09073.5 CDI86175.1 - 2.6 7.0 20.8 0.19 10.7 5.9 2.2 2 0 0 2 2 2 0 BUD22 Gly-zipper_OmpA PF13436.1 CDI86175.1 - 4.6 6.9 14.6 15 5.2 10.1 1.8 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain DUF4446 PF14584.1 CDI86177.1 - 0.0028 17.4 1.9 0.0033 17.2 1.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4446) DUF3617 PF12276.3 CDI86177.1 - 0.026 13.9 5.7 0.031 13.7 4.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3617) Spt20 PF12090.3 CDI86177.1 - 0.031 13.6 3.8 0.028 13.7 2.6 1.1 1 0 0 1 1 1 0 Spt20 family Trypan_PARP PF05887.6 CDI86177.1 - 0.036 13.8 0.0 0.045 13.5 0.0 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Cyclin_C PF02984.14 CDI86177.1 - 0.038 13.9 5.6 0.066 13.1 3.7 1.6 1 1 0 1 1 1 0 Cyclin, C-terminal domain Ctr PF04145.10 CDI86177.1 - 0.045 13.7 1.5 0.057 13.4 1.0 1.2 1 0 0 1 1 1 0 Ctr copper transporter family RAB3GAP2_N PF14655.1 CDI86177.1 - 0.079 11.9 4.5 0.088 11.7 3.1 1.1 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Serinc PF03348.10 CDI86177.1 - 0.083 11.5 4.8 0.083 11.5 3.3 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) Med15 PF09606.5 CDI86177.1 - 0.092 10.9 19.7 0.083 11.0 13.7 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Peptidase_S15 PF02129.13 CDI86177.1 - 0.11 11.9 6.3 0.11 11.9 4.4 1.0 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Shadoo PF14999.1 CDI86177.1 - 0.15 11.9 3.0 0.24 11.2 2.1 1.4 1 0 0 1 1 1 0 Shadow of prion protein, neuroprotective R_equi_Vir PF05526.6 CDI86177.1 - 0.16 11.6 5.8 0.18 11.4 4.0 1.1 1 0 0 1 1 1 0 Rhodococcus equi virulence-associated protein DUF2232 PF09991.4 CDI86177.1 - 0.23 10.4 2.0 0.28 10.1 1.4 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) FimP PF09766.4 CDI86177.1 - 0.23 10.4 13.4 0.23 10.5 9.3 1.0 1 0 0 1 1 1 0 Fms-interacting protein DUF2215 PF10225.4 CDI86177.1 - 0.33 10.3 1.9 0.32 10.4 1.3 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) DUF4179 PF13786.1 CDI86177.1 - 0.6 10.3 5.7 1.4 9.1 4.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4179) DDHD PF02862.12 CDI86177.1 - 0.84 9.3 4.9 0.85 9.3 3.4 1.0 1 0 0 1 1 1 0 DDHD domain SHR3_chaperone PF08229.6 CDI86177.1 - 1.3 7.9 4.1 1.4 7.8 2.8 1.3 1 0 0 1 1 1 0 ER membrane protein SH3 DUF4557 PF15101.1 CDI86177.1 - 1.4 8.7 11.3 1.4 8.7 7.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) DOR PF14839.1 CDI86177.1 - 2.6 7.7 16.4 2.7 7.6 11.3 1.0 1 0 0 1 1 1 0 DOR family RskA PF10099.4 CDI86177.1 - 3.2 7.4 15.8 6.2 6.5 10.9 1.5 1 1 0 1 1 1 0 Anti-sigma-K factor rskA FCP1_C PF09309.5 CDI86177.1 - 5.8 6.1 10.8 6.4 6.0 7.5 1.2 1 0 0 1 1 1 0 FCP1, C-terminal PAT1 PF09770.4 CDI86179.1 - 0.00033 19.0 42.8 0.00033 19.0 29.6 1.8 2 0 0 2 2 2 1 Topoisomerase II-associated protein PAT1 WD40 PF00400.27 CDI86179.1 - 0.00033 20.4 0.4 0.0015 18.3 0.0 2.1 2 0 0 2 2 2 1 WD domain, G-beta repeat HlyD_2 PF12700.2 CDI86179.1 - 0.21 10.6 14.6 0.45 9.6 10.1 1.5 1 0 0 1 1 1 0 HlyD family secretion protein AAA_23 PF13476.1 CDI86179.1 - 0.86 9.8 23.3 1.4 9.1 16.2 1.3 1 0 0 1 1 1 0 AAA domain LMBR1 PF04791.11 CDI86179.1 - 1.7 7.1 10.0 12 4.3 6.9 2.2 1 1 0 1 1 1 0 LMBR1-like membrane protein SAGA-Tad1 PF12767.2 CDI86179.1 - 1.8 8.1 28.0 0.23 11.0 16.5 1.7 2 0 0 2 2 2 0 Transcriptional regulator of RNA polII, SAGA, subunit Dicty_REP PF05086.7 CDI86179.1 - 6.4 4.3 7.0 10 3.7 4.9 1.3 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Med15 PF09606.5 CDI86180.1 - 0.0014 16.9 47.2 0.0015 16.8 32.7 1.1 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal MRP-S31 PF15433.1 CDI86180.1 - 0.0079 15.6 20.4 0.0093 15.4 14.1 1.2 1 0 0 1 1 1 1 Mitochondrial 28S ribosomal protein S31 RskA PF10099.4 CDI86180.1 - 0.018 14.8 26.6 0.33 10.6 8.2 2.2 1 1 1 2 2 2 0 Anti-sigma-K factor rskA PAT1 PF09770.4 CDI86180.1 - 0.048 11.9 37.2 0.058 11.6 25.8 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF2029 PF09594.5 CDI86180.1 - 0.061 12.8 2.8 0.099 12.1 1.9 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2029) DUF3357 PF11837.3 CDI86180.1 - 0.075 12.8 0.0 0.075 12.8 0.0 2.9 1 1 1 2 2 2 0 Domain of unknown function (DUF3357) DUF4647 PF15504.1 CDI86180.1 - 0.077 11.8 21.5 0.098 11.4 14.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4647) Macoilin PF09726.4 CDI86180.1 - 0.26 9.5 19.2 0.36 9.0 13.3 1.3 1 0 0 1 1 1 0 Transmembrane protein Pap_E4 PF02711.9 CDI86180.1 - 0.99 10.2 15.5 3.3 8.6 2.5 2.3 2 0 0 2 2 2 0 E4 protein PAXIP1_C PF15364.1 CDI86180.1 - 1.4 8.8 18.7 3.6 7.5 3.7 2.1 2 0 0 2 2 2 0 PAXIP1-associated-protein-1 C term PTIP binding protein DUF3449 PF11931.3 CDI86180.1 - 2.4 7.6 16.7 0.76 9.2 1.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3449) Parvo_coat PF00740.13 CDI86180.1 - 2.4 7.0 20.4 2.9 6.7 14.2 1.0 1 0 0 1 1 1 0 Parvovirus coat protein VP2 DUF1675 PF07897.6 CDI86180.1 - 3.3 7.4 18.1 4.5 7.0 12.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) zf-DHHC PF01529.15 CDI86180.1 - 4.6 6.6 9.4 0.7 9.2 1.8 2.1 2 0 0 2 2 2 0 DHHC palmitoyltransferase BRF1 PF07741.8 CDI86180.1 - 5.7 7.2 22.0 0.56 10.4 5.2 3.1 3 0 0 3 3 3 0 Brf1-like TBP-binding domain PDR_CDR PF06422.7 CDI86180.1 - 6.2 6.5 7.3 9.2 5.9 0.2 2.7 1 1 2 3 3 3 0 CDR ABC transporter CIAPIN1 PF05093.8 CDI86180.1 - 6.4 6.9 18.1 3.8 7.6 4.8 2.4 2 0 0 2 2 2 0 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis DUF4366 PF14283.1 CDI86180.1 - 6.5 6.1 14.2 13 5.1 9.9 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4366) MLANA PF14991.1 CDI86180.1 - 7.2 6.6 8.0 0.31 11.0 0.5 2.2 1 1 2 3 3 3 0 Protein melan-A U1snRNP70_N PF12220.3 CDI86180.1 - 7.6 6.9 17.4 3.9 7.8 5.2 2.2 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal zf-C2H2_4 PF13894.1 CDI86181.1 - 0.00089 19.4 3.7 0.13 12.7 1.2 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger IER PF05760.7 CDI86182.1 - 0.013 15.4 15.9 0.02 14.8 11.0 1.3 1 0 0 1 1 1 0 Immediate early response protein (IER) DUF572 PF04502.8 CDI86182.1 - 0.073 12.2 3.6 0.086 12.0 2.5 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF3452 PF11934.3 CDI86182.1 - 0.08 12.2 0.1 0.13 11.5 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3452) DUF2217 PF10265.4 CDI86182.1 - 0.41 9.3 5.2 0.53 8.9 3.6 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) Herpes_TAF50 PF03326.8 CDI86182.1 - 0.56 9.0 23.9 0.84 8.5 16.6 1.3 1 0 0 1 1 1 0 Herpesvirus transcription activation factor (transactivator) SOBP PF15279.1 CDI86182.1 - 0.86 9.9 11.8 1 9.7 8.2 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein CPSF100_C PF13299.1 CDI86182.1 - 0.99 9.5 5.1 1.7 8.8 3.5 1.4 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Pol_alpha_B_N PF08418.5 CDI86182.1 - 1.9 7.9 13.8 2.3 7.6 9.6 1.2 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal TFIIA PF03153.8 CDI86183.1 - 1.7 8.4 23.3 2.4 7.9 16.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Med15 PF09606.5 CDI86183.1 - 3.9 5.5 31.0 5.4 5.0 21.5 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Menin PF05053.8 CDI86183.1 - 3.9 5.5 9.0 4.4 5.3 6.3 1.1 1 0 0 1 1 1 0 Menin Cwf_Cwc_15 PF04889.7 CDI86184.1 - 0.0012 18.6 40.5 0.0016 18.2 28.1 1.1 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein Macoilin PF09726.4 CDI86184.1 - 3.5 5.8 36.3 5.9 5.0 25.1 1.3 1 0 0 1 1 1 0 Transmembrane protein DUF4647 PF15504.1 CDI86184.1 - 3.7 6.3 46.5 5.8 5.6 32.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4647) DUF4207 PF13904.1 CDI86184.1 - 4.1 6.7 73.4 5.8 6.2 50.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4207) Na_trans_assoc PF06512.8 CDI86184.1 - 7.6 6.4 28.8 11 5.9 19.9 1.2 1 0 0 1 1 1 0 Sodium ion transport-associated Abhydrolase_5 PF12695.2 CDI86185.1 - 5.9e-05 22.8 0.0 5.9e-05 22.8 0.0 2.7 2 1 0 2 2 2 1 Alpha/beta hydrolase family MecA PF05389.7 CDI86185.1 - 0.12 11.8 2.3 0.17 11.3 1.6 1.1 1 0 0 1 1 1 0 Negative regulator of genetic competence (MecA) Activator_LAG-3 PF11498.3 CDI86185.1 - 0.41 9.3 19.4 0.83 8.3 13.5 1.5 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Corona_nucleoca PF00937.13 CDI86185.1 - 0.83 8.5 12.1 0.21 10.4 4.4 2.0 2 0 0 2 2 2 0 Coronavirus nucleocapsid protein Fes1 PF08609.5 CDI86185.1 - 1.4 9.4 5.6 0.89 10.0 1.4 2.3 2 1 0 2 2 2 0 Nucleotide exchange factor Fes1 Med15 PF09606.5 CDI86186.1 - 4.2e-06 25.2 39.3 4.2e-06 25.2 27.3 7.7 3 1 3 7 7 7 2 ARC105 or Med15 subunit of Mediator complex non-fungal OmpH PF03938.9 CDI86186.1 - 0.0012 18.8 22.8 0.0012 18.8 15.8 10.0 4 2 3 8 8 8 2 Outer membrane protein (OmpH-like) Dehydrin PF00257.14 CDI86186.1 - 0.0036 17.6 4.5 0.0036 17.6 3.1 14.0 10 4 0 10 10 10 2 Dehydrin Metallophos PF00149.23 CDI86190.1 - 6.2e-09 35.5 0.0 2.5e-08 33.5 0.0 2.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase ABC_tran PF00005.22 CDI86191.1 - 1.1e-22 80.7 0.0 1.7e-22 80.2 0.0 1.2 1 0 0 1 1 1 1 ABC transporter ABC2_membrane PF01061.19 CDI86191.1 - 2.5e-21 75.8 18.7 3.9e-21 75.2 13.0 1.3 1 0 0 1 1 1 1 ABC-2 type transporter AAA_25 PF13481.1 CDI86191.1 - 2.8e-06 26.8 0.9 0.0065 15.8 0.0 2.3 2 0 0 2 2 2 2 AAA domain ABC2_membrane_3 PF12698.2 CDI86191.1 - 5e-06 25.7 14.4 5e-06 25.7 10.0 1.9 2 0 0 2 2 2 1 ABC-2 family transporter protein AAA_21 PF13304.1 CDI86191.1 - 0.00037 20.5 0.0 0.037 13.9 0.0 2.1 1 1 1 2 2 2 1 AAA domain AAA_17 PF13207.1 CDI86191.1 - 0.0031 18.3 0.0 0.0065 17.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain DUF258 PF03193.11 CDI86191.1 - 0.0066 15.6 0.0 0.011 14.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 CDI86191.1 - 0.019 14.9 0.0 0.045 13.7 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.1 CDI86191.1 - 0.033 14.3 0.1 0.18 11.9 0.2 2.0 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.10 CDI86191.1 - 0.042 12.5 0.0 0.061 11.9 0.0 1.1 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein AAA_28 PF13521.1 CDI86191.1 - 0.052 13.5 0.0 0.088 12.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 CDI86191.1 - 0.1 12.1 0.4 0.25 10.8 0.1 1.8 2 0 0 2 2 1 0 P-loop containing region of AAA domain AAA_18 PF13238.1 CDI86191.1 - 0.14 12.4 0.0 0.22 11.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 CDI86191.1 - 0.15 12.2 0.0 0.26 11.4 0.0 1.4 1 0 0 1 1 1 0 RNA helicase NACHT PF05729.7 CDI86191.1 - 0.15 11.7 0.2 0.34 10.5 0.1 1.6 1 0 0 1 1 1 0 NACHT domain PduV-EutP PF10662.4 CDI86191.1 - 0.16 11.4 0.1 0.3 10.5 0.0 1.3 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_10 PF12846.2 CDI86191.1 - 0.18 11.2 0.0 0.27 10.6 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain Arch_ATPase PF01637.13 CDI86191.1 - 0.28 10.8 0.0 0.41 10.3 0.0 1.2 1 0 0 1 1 1 0 Archaeal ATPase AAA_23 PF13476.1 CDI86191.1 - 0.32 11.3 0.0 0.48 10.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain Helicase_C PF00271.26 CDI86192.1 - 5.8e-09 35.6 0.0 1.2e-08 34.6 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 CDI86192.1 - 7.1e-08 32.1 0.0 0.00026 20.5 0.0 2.7 3 0 0 3 3 3 2 DEAD/DEAH box helicase HHH_5 PF14520.1 CDI86192.1 - 0.0017 18.5 0.0 0.0058 16.7 0.0 1.9 1 0 0 1 1 1 1 Helix-hairpin-helix domain Trs65 PF12735.2 CDI86193.1 - 1.3e-12 47.6 1.3 7.5e-06 25.4 0.0 2.1 2 0 0 2 2 2 2 TRAPP trafficking subunit Trs65 DUF974 PF06159.8 CDI86193.1 - 5e-07 29.4 2.2 0.0029 17.1 0.1 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF974) Gryzun PF07919.7 CDI86193.1 - 6.3e-07 28.0 0.3 1.1e-06 27.3 0.1 1.2 1 1 0 1 1 1 1 Gryzun, putative trafficking through Golgi Transglut_C PF00927.17 CDI86193.1 - 0.034 14.1 0.0 0.064 13.2 0.0 1.4 1 0 0 1 1 1 0 Transglutaminase family, C-terminal ig like domain Peptidase_M16 PF00675.15 CDI86194.1 - 3.4e-43 146.9 0.7 1.2e-42 145.1 0.0 2.3 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 CDI86194.1 - 5.3e-12 45.7 0.7 4.9e-08 32.8 0.0 3.0 3 0 0 3 3 3 2 Peptidase M16 inactive domain Asp PF00026.18 CDI86195.1 - 3.3e-19 69.3 0.0 1.8e-09 37.3 0.0 3.1 2 1 1 3 3 3 3 Eukaryotic aspartyl protease Amidohydro_2 PF04909.9 CDI86197.1 - 7.5e-08 32.2 0.5 1.9e-07 30.9 0.4 1.7 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.15 CDI86197.1 - 0.079 12.6 0.2 0.25 10.9 0.1 1.7 1 1 0 1 1 1 0 Amidohydrolase family V-SNARE_C PF12352.3 CDI86198.1 - 2.4e-06 27.5 2.6 2.4e-06 27.5 1.8 2.1 3 0 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.8 CDI86198.1 - 0.098 12.3 0.2 0.098 12.3 0.1 2.4 3 1 0 3 3 3 0 Sec20 Terminase_4 PF05119.7 CDI86198.1 - 0.1 12.7 2.9 1.3 9.2 0.6 2.6 2 1 0 2 2 2 0 Phage terminase, small subunit SpaB_C PF14028.1 CDI86198.1 - 4.8 6.6 7.9 5.8 6.3 5.1 1.4 1 1 0 1 1 1 0 SpaB C-terminal domain Ribosomal_L28 PF00830.14 CDI86199.1 - 3.9e-08 33.0 0.1 8.8e-08 31.8 0.1 1.6 1 0 0 1 1 1 1 Ribosomal L28 family SET PF00856.23 CDI86201.1 - 1.1e-06 29.0 1.1 0.084 13.1 0.0 3.8 3 1 0 4 4 4 2 SET domain RR_TM4-6 PF06459.7 CDI86201.1 - 0.35 10.7 3.1 0.75 9.6 2.1 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 TFIIF_beta PF02270.10 CDI86202.1 - 0.078 12.7 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor IIF, beta subunit TT_ORF1 PF02956.9 CDI86202.1 - 0.4 9.0 3.8 0.53 8.6 2.7 1.1 1 0 0 1 1 1 0 TT viral orf 1 DEAD PF00270.24 CDI86204.1 - 4.8e-12 45.7 0.0 1.6e-11 43.9 0.0 1.9 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF3984 PF13136.1 CDI86206.1 - 0.0022 17.2 9.8 0.0052 16.0 4.9 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3984) Pex14_N PF04695.8 CDI86206.1 - 0.0036 17.3 9.6 0.0036 17.3 6.7 2.3 1 1 1 2 2 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region IncA PF04156.9 CDI86206.1 - 0.0062 16.1 1.6 0.0062 16.1 1.1 2.4 2 0 0 2 2 2 1 IncA protein Na_trans_assoc PF06512.8 CDI86206.1 - 0.017 15.0 4.3 0.017 15.0 3.0 2.2 2 0 0 2 2 2 0 Sodium ion transport-associated APC_CDC26 PF10471.4 CDI86206.1 - 0.021 15.5 26.0 0.61 10.8 0.1 3.4 3 0 0 3 3 3 0 Anaphase-promoting complex APC subunit 1 DUF2749 PF10907.3 CDI86206.1 - 0.03 14.2 0.3 0.03 14.2 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2749) PRP1_N PF06424.7 CDI86206.1 - 0.077 13.3 4.8 0.18 12.1 0.5 2.1 2 0 0 2 2 2 0 PRP1 splicing factor, N-terminal SOBP PF15279.1 CDI86206.1 - 0.13 12.6 9.0 0.17 12.2 6.2 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein Paramyxo_C PF01692.13 CDI86206.1 - 0.26 10.8 8.8 0.074 12.6 2.4 2.1 2 0 0 2 2 2 0 Paramyxovirus non-structural protein c Secretin_N_2 PF07655.8 CDI86206.1 - 0.55 10.6 29.0 0.37 11.2 17.2 2.2 2 0 0 2 2 2 0 Secretin N-terminal domain RskA PF10099.4 CDI86206.1 - 1.3 8.7 17.5 2.2 8.0 12.2 1.5 1 1 0 1 1 1 0 Anti-sigma-K factor rskA Apc15p PF05841.6 CDI86206.1 - 1.5 9.5 15.5 8.5 7.1 6.4 2.4 2 0 0 2 2 2 0 Apc15p protein MRI PF15325.1 CDI86206.1 - 1.9 9.5 13.0 6.3 7.8 6.3 2.5 2 0 0 2 2 2 0 Modulator of retrovirus infection RAP1 PF07218.6 CDI86206.1 - 2.9 5.8 19.4 3.9 5.4 13.5 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Bul1_N PF04425.7 CDI86206.1 - 5.8 5.3 9.6 2.9 6.3 3.8 2.0 2 0 0 2 2 2 0 Bul1 N terminus ICAP-1_inte_bdg PF10480.4 CDI86206.1 - 7.7 6.2 12.6 11 5.6 8.7 1.2 1 0 0 1 1 1 0 Beta-1 integrin binding protein Phostensin_N PF13916.1 CDI86206.1 - 8.8 6.3 15.3 2 8.4 0.2 2.6 2 0 0 2 2 2 0 PP1-regulatory protein, Phostensin N-terminal DNA_pol_viral_N PF00242.12 CDI86209.1 - 0.0053 15.8 11.0 0.0058 15.7 7.6 1.1 1 0 0 1 1 1 1 DNA polymerase (viral) N-terminal domain POX PF07526.6 CDI86209.1 - 0.0066 16.6 0.2 0.0081 16.4 0.2 1.2 1 0 0 1 1 1 1 Associated with HOX zf-UBP PF02148.14 CDI86209.1 - 0.012 15.6 0.6 0.019 15.0 0.4 1.3 1 0 0 1 1 1 0 Zn-finger in ubiquitin-hydrolases and other protein DUF2290 PF10053.4 CDI86209.1 - 0.085 12.1 0.1 0.1 11.8 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2290) zf-HIT PF04438.11 CDI86209.1 - 0.17 11.5 3.1 0.24 11.0 2.1 1.2 1 0 0 1 1 1 0 HIT zinc finger Pox_A12 PF04651.8 CDI86209.1 - 0.26 11.4 10.6 0.33 11.0 7.3 1.2 1 0 0 1 1 1 0 Poxvirus A12 protein MIP-T3 PF10243.4 CDI86209.1 - 0.43 9.0 4.8 0.44 8.9 3.3 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DUF4639 PF15479.1 CDI86209.1 - 0.43 9.1 6.0 0.49 8.9 4.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4639) SSP160 PF06933.6 CDI86209.1 - 0.57 8.0 19.1 0.58 8.0 13.2 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 RAP1 PF07218.6 CDI86209.1 - 0.59 8.1 21.1 0.65 8.0 14.6 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Macoilin PF09726.4 CDI86209.1 - 0.63 8.2 18.7 0.69 8.1 13.0 1.0 1 0 0 1 1 1 0 Transmembrane protein Ima1_N PF09779.4 CDI86209.1 - 0.75 10.2 8.1 3.9 7.9 5.6 1.9 1 1 0 1 1 1 0 Ima1 N-terminal domain DUF4614 PF15391.1 CDI86209.1 - 1.9 8.2 13.0 2.5 7.8 9.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) Period_C PF12114.3 CDI86209.1 - 3.8 7.0 22.9 5.1 6.6 15.9 1.3 1 0 0 1 1 1 0 Period protein 2/3C-terminal region Apt1 PF10351.4 CDI86209.1 - 6.3 5.5 14.4 7.4 5.3 10.0 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF755 PF05501.6 CDI86210.1 - 0.00024 21.1 16.1 0.00024 21.1 11.2 11.7 8 4 3 11 11 11 1 Domain of unknown function (DUF755) Kinase-like PF14531.1 CDI86212.1 - 6.8e-07 28.5 0.0 1.1e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase PF00069.20 CDI86212.1 - 0.1 11.7 0.0 0.17 10.9 0.0 1.4 1 0 0 1 1 1 0 Protein kinase domain GIDE PF12483.3 CDI86213.1 - 0.083 12.2 0.3 0.11 11.8 0.2 1.2 1 0 0 1 1 1 0 E3 Ubiquitin ligase TAT_signal PF10518.4 CDI86213.1 - 0.085 12.8 0.5 0.085 12.8 0.3 2.5 2 0 0 2 2 2 0 TAT (twin-arginine translocation) pathway signal sequence ATP-synt_E PF05680.7 CDI86213.1 - 0.52 10.2 6.3 1.1 9.2 4.4 1.6 1 0 0 1 1 1 0 ATP synthase E chain OAD_gamma PF04277.8 CDI86213.1 - 8.7 6.8 7.0 0.52 10.7 1.0 1.7 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain Ribosomal_60s PF00428.14 CDI86214.1 - 0.01 16.2 7.3 0.01 16.2 5.0 3.9 3 1 0 3 3 3 0 60s Acidic ribosomal protein Peptidase_S49_N PF08496.5 CDI86214.1 - 0.016 15.0 2.5 0.016 15.0 1.7 2.4 2 0 0 2 2 2 0 Peptidase family S49 N-terminal THRAP3_BCLAF1 PF15440.1 CDI86214.1 - 0.047 12.3 37.7 0.077 11.6 26.1 1.3 1 0 0 1 1 1 0 THRAP3/BCLAF1 family Glyco_hydro_3_C PF01915.17 CDI86214.1 - 0.69 9.3 19.9 1.6 8.2 1.7 2.3 2 0 0 2 2 2 0 Glycosyl hydrolase family 3 C-terminal domain CemA PF03040.9 CDI86214.1 - 1.6 8.2 16.2 0.47 10.0 2.5 2.1 2 0 0 2 2 2 0 CemA family Glyco_hydro_1 PF00232.13 CDI86214.1 - 4.8 5.2 21.1 30 2.6 14.6 1.9 1 1 0 1 1 1 0 Glycosyl hydrolase family 1 FimP PF09766.4 CDI86216.1 - 0.074 12.1 28.9 0.51 9.3 10.0 2.1 2 0 0 2 2 2 0 Fms-interacting protein DUF3801 PF12687.2 CDI86216.1 - 0.16 11.5 16.6 0.53 9.8 5.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3801) MAT1 PF06391.8 CDI86216.1 - 2.8 7.4 19.0 0.63 9.5 4.5 2.1 2 0 0 2 2 2 0 CDK-activating kinase assembly factor MAT1 Peptidase_U57 PF05582.7 CDI86216.1 - 2.8 6.8 15.2 0.98 8.3 3.6 2.1 2 0 0 2 2 2 0 YabG peptidase U57 DUF966 PF06136.8 CDI86216.1 - 2.8 7.2 27.9 3.3 7.0 19.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Pap_E4 PF02711.9 CDI86216.1 - 5.5 7.8 21.7 7.3 7.4 4.1 2.3 2 0 0 2 2 2 0 E4 protein DUF2232 PF09991.4 CDI86216.1 - 5.7 5.8 10.7 0.17 10.8 0.9 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2232) PLRV_ORF5 PF01690.12 CDI86216.1 - 6 5.8 23.8 6.9 5.7 16.5 1.0 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein IPP-2 PF04979.9 CDI86216.1 - 6.4 7.0 19.5 6.6 6.9 3.0 2.2 2 0 0 2 2 2 0 Protein phosphatase inhibitor 2 (IPP-2) PH_5 PF15405.1 CDI86216.1 - 8.3 6.3 16.6 6 6.8 3.0 2.2 2 0 0 2 2 2 0 Pleckstrin homology domain DUF2899 PF11449.3 CDI86216.1 - 9.1 5.3 11.7 33 3.5 8.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2899) Glyco_hydro_9 PF00759.14 CDI86217.1 - 0.11 11.3 6.7 0.11 11.4 4.6 1.0 1 0 0 1 1 1 0 Glycosyl hydrolase family 9 Macoilin PF09726.4 CDI86217.1 - 0.13 10.5 14.0 0.14 10.4 9.7 1.0 1 0 0 1 1 1 0 Transmembrane protein Prenyltrans_2 PF13249.1 CDI86217.1 - 0.14 12.5 3.1 0.15 12.4 2.1 1.1 1 0 0 1 1 1 0 Prenyltransferase-like DUF4139 PF13598.1 CDI86217.1 - 0.28 10.4 9.1 0.3 10.3 6.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4139) UPF0565 PF10561.4 CDI86217.1 - 0.67 8.7 3.8 0.77 8.5 2.7 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0565 DUF3138 PF11336.3 CDI86217.1 - 0.69 8.0 14.9 0.73 7.9 10.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) DUF2057 PF09829.4 CDI86217.1 - 0.77 9.3 9.0 0.91 9.1 6.3 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2057) IER PF05760.7 CDI86217.1 - 1.1 9.0 6.7 1.2 9.0 4.7 1.0 1 0 0 1 1 1 0 Immediate early response protein (IER) DUF724 PF05266.9 CDI86217.1 - 1.3 8.6 7.4 1.4 8.4 5.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF724) FGF-BP1 PF06473.7 CDI86217.1 - 1.6 8.2 4.8 1.7 8.1 3.3 1.0 1 0 0 1 1 1 0 FGF binding protein 1 (FGF-BP1) DUF3280 PF11684.3 CDI86217.1 - 5.7 7.1 13.4 6.6 6.9 9.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2380) Med15 PF09606.5 CDI86217.1 - 9.7 4.2 18.9 10 4.2 13.1 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Spt20 PF12090.3 CDI86219.1 - 0.028 13.7 0.5 0.037 13.3 0.3 1.3 1 0 0 1 1 1 0 Spt20 family SGT1 PF07093.6 CDI86219.1 - 0.029 12.7 0.6 0.038 12.3 0.4 1.1 1 0 0 1 1 1 0 SGT1 protein FCP1_C PF09309.5 CDI86219.1 - 0.1 11.8 3.1 0.083 12.1 0.6 2.1 2 0 0 2 2 2 0 FCP1, C-terminal Bcl-2 PF00452.14 CDI86219.1 - 0.11 12.6 0.0 0.11 12.6 0.0 2.1 2 0 0 2 2 2 0 Apoptosis regulator proteins, Bcl-2 family Pol_alpha_B_N PF08418.5 CDI86219.1 - 0.2 11.1 7.3 1.1 8.7 5.0 2.1 1 1 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal DUF3373 PF11853.3 CDI86219.1 - 1.4 7.3 4.7 2.7 6.4 3.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) Suf PF05843.9 CDI86219.1 - 2 8.0 6.2 0.93 9.1 2.8 1.5 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) ERF PF04404.7 CDI86219.1 - 2.1 7.8 11.4 4.2 6.8 7.9 1.5 1 0 0 1 1 1 0 ERF superfamily FimP PF09766.4 CDI86219.1 - 3.3 6.6 11.6 4.9 6.1 8.0 1.1 1 0 0 1 1 1 0 Fms-interacting protein Ribosomal_60s PF00428.14 CDI86220.1 - 0.00052 20.3 2.3 0.00057 20.2 1.6 1.2 1 0 0 1 1 1 1 60s Acidic ribosomal protein Myc_N PF01056.13 CDI86220.1 - 0.19 10.8 0.7 0.18 10.9 0.5 1.0 1 0 0 1 1 1 0 Myc amino-terminal region Radial_spoke PF04712.7 CDI86220.1 - 2.1 6.9 5.4 2.4 6.7 3.8 1.0 1 0 0 1 1 1 0 Radial spokehead-like protein PBP_sp32 PF07222.7 CDI86220.1 - 3.6 6.7 10.5 4.6 6.3 7.3 1.1 1 0 0 1 1 1 0 Proacrosin binding protein sp32 DUF3682 PF12446.3 CDI86220.1 - 5.9 7.1 12.4 7.9 6.7 8.6 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3682) Sporozoite_P67 PF05642.6 CDI86220.1 - 7.8 4.2 6.2 8.2 4.1 4.3 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Collagen PF01391.13 CDI86221.1 - 2.5e-06 26.9 23.2 2.5e-06 26.9 16.1 2.7 3 0 0 3 3 3 1 Collagen triple helix repeat (20 copies) rve PF00665.21 CDI86222.1 - 5.2e-17 62.0 0.1 2.5e-16 59.8 0.0 2.1 3 0 0 3 3 3 1 Integrase core domain gag-asp_proteas PF13975.1 CDI86223.1 - 3.7e-16 58.7 0.6 2.8e-07 30.2 0.1 2.5 2 0 0 2 2 2 2 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 CDI86223.1 - 5.5e-16 58.8 0.0 1.1e-06 29.0 0.0 2.5 2 0 0 2 2 2 2 Aspartyl protease RVP_2 PF08284.6 CDI86223.1 - 1.8e-09 37.6 0.0 0.00067 19.6 0.0 2.9 3 0 0 3 3 3 2 Retroviral aspartyl protease RVP PF00077.15 CDI86223.1 - 1.9e-08 34.0 0.0 0.0066 16.3 0.0 3.3 2 2 0 2 2 2 2 Retroviral aspartyl protease Asp_protease PF09668.5 CDI86223.1 - 0.00014 21.4 0.0 0.0051 16.3 0.0 2.4 2 1 0 2 2 2 1 Aspartyl protease zf-CCHC PF00098.18 CDI86223.1 - 0.053 13.4 10.3 0.49 10.4 0.7 2.6 2 0 0 2 2 2 0 Zinc knuckle DnaJ_CXXCXGXG PF00684.14 CDI86223.1 - 0.18 11.8 9.3 7.8 6.6 4.5 2.6 2 0 0 2 2 2 0 DnaJ central domain FimP PF09766.4 CDI86225.1 - 0.00023 20.3 5.2 0.00026 20.1 3.6 1.1 1 0 0 1 1 1 1 Fms-interacting protein DUF775 PF05603.7 CDI86225.1 - 0.0011 18.5 3.3 0.0016 17.9 2.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF775) Spt20 PF12090.3 CDI86225.1 - 0.0029 16.9 2.2 0.0035 16.6 1.5 1.2 1 0 0 1 1 1 1 Spt20 family RAB3GAP2_N PF14655.1 CDI86225.1 - 0.022 13.7 4.2 0.029 13.3 2.9 1.1 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus FHIPEP PF00771.15 CDI86225.1 - 0.043 12.1 3.4 0.052 11.8 2.3 1.1 1 0 0 1 1 1 0 FHIPEP family PRCC PF10253.4 CDI86225.1 - 0.12 13.0 16.8 0.37 11.4 3.6 2.1 2 0 0 2 2 2 0 Mitotic checkpoint regulator, MAD2B-interacting Claudin_2 PF13903.1 CDI86225.1 - 0.36 10.5 2.6 0.62 9.7 1.8 1.4 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction TCP PF03634.8 CDI86225.1 - 0.82 10.0 11.5 0.3 11.4 3.0 2.3 2 0 0 2 2 2 0 TCP family transcription factor Serinc PF03348.10 CDI86225.1 - 0.95 8.0 3.4 1.3 7.6 2.3 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) DUF912 PF06024.7 CDI86225.1 - 2.8 8.0 6.0 6.3 6.9 4.2 1.5 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) RskA PF10099.4 CDI86225.1 - 3.2 7.4 35.7 0.26 10.9 12.3 2.3 2 0 0 2 2 2 0 Anti-sigma-K factor rskA PAT1 PF09770.4 CDI86225.1 - 4.4 5.4 19.8 0.096 10.9 8.4 1.8 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 UPF0560 PF10577.4 CDI86225.1 - 8.7 4.4 11.2 13 3.8 7.8 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 MIP-T3 PF10243.4 CDI86226.1 - 0.01 14.3 38.5 0.014 13.9 26.7 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Macoilin PF09726.4 CDI86226.1 - 0.62 8.2 55.7 0.79 7.9 38.6 1.1 1 0 0 1 1 1 0 Transmembrane protein SLD3 PF08639.5 CDI86226.1 - 6.1 5.3 49.9 7.9 4.9 34.6 1.1 1 0 0 1 1 1 0 DNA replication regulator SLD3 CAP_N PF01213.14 CDI86227.1 - 0.00046 19.5 3.5 0.0005 19.4 2.4 1.1 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal Mito_fiss_reg PF05308.6 CDI86227.1 - 0.018 14.4 18.1 0.024 14.0 12.6 1.1 1 0 0 1 1 1 0 Mitochondrial fission regulator DUF1510 PF07423.6 CDI86227.1 - 0.029 13.7 11.2 0.041 13.2 7.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DUF1183 PF06682.7 CDI86227.1 - 0.17 11.4 11.3 0.22 11.0 7.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) Herpes_DNAp_acc PF04929.7 CDI86227.1 - 0.18 10.7 13.4 0.21 10.5 9.3 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Rtf2 PF04641.7 CDI86227.1 - 0.31 10.2 10.8 0.4 9.8 7.5 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger POR_N PF01855.14 CDI86227.1 - 0.32 10.4 3.3 0.39 10.1 2.3 1.1 1 0 0 1 1 1 0 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg FLO_LFY PF01698.11 CDI86227.1 - 0.39 9.5 8.6 0.51 9.1 5.9 1.2 1 0 0 1 1 1 0 Floricaula / Leafy protein FAM60A PF15396.1 CDI86227.1 - 0.45 10.2 10.0 0.52 10.0 7.0 1.1 1 0 0 1 1 1 0 Protein Family FAM60A NeA_P2 PF12312.3 CDI86227.1 - 0.45 9.6 3.4 0.52 9.5 2.4 1.1 1 0 0 1 1 1 0 Nepovirus subgroup A polyprotein PAT1 PF09770.4 CDI86227.1 - 0.61 8.2 49.6 0.66 8.1 34.4 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 UPF0565 PF10561.4 CDI86227.1 - 0.74 8.6 7.1 0.97 8.2 4.9 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0565 SID-1_RNA_chan PF13965.1 CDI86227.1 - 0.98 7.5 4.4 1.3 7.0 3.0 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 TMEM51 PF15345.1 CDI86227.1 - 1.4 8.5 20.5 0.061 13.0 5.0 2.1 2 0 0 2 2 2 0 Transmembrane protein 51 GRP PF07172.6 CDI86227.1 - 1.6 9.2 6.7 0.47 10.9 0.3 2.1 2 0 0 2 2 2 0 Glycine rich protein family Senescence_reg PF04520.8 CDI86227.1 - 2 8.8 8.1 2.2 8.7 5.6 1.1 1 0 0 1 1 1 0 Senescence regulator Ycf1 PF05758.7 CDI86227.1 - 2.4 5.7 11.7 2.9 5.4 8.1 1.1 1 0 0 1 1 1 0 Ycf1 Peptidase_S49_N PF08496.5 CDI86227.1 - 3.1 7.5 13.4 1.4 8.6 2.7 2.1 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Peroxin-13_N PF04088.8 CDI86227.1 - 3.2 7.6 9.2 1.5 8.7 1.5 2.1 2 0 0 2 2 2 0 Peroxin 13, N-terminal region Gastrin PF00918.12 CDI86227.1 - 3.5 8.4 19.1 5 7.9 13.3 1.2 1 0 0 1 1 1 0 Gastrin/cholecystokinin family DUF4045 PF13254.1 CDI86227.1 - 4.3 6.5 14.3 5.2 6.2 9.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Hid1 PF12722.2 CDI86227.1 - 5.8 4.4 16.2 6.7 4.2 11.2 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SPX PF03105.14 CDI86227.1 - 6.1 6.5 15.8 8 6.1 11.0 1.1 1 0 0 1 1 1 0 SPX domain Tetraspannin PF00335.15 CDI86227.1 - 7.1 5.8 5.8 21 4.3 4.0 1.7 1 1 0 1 1 1 0 Tetraspanin family DUF4613 PF15390.1 CDI86227.1 - 7.5 4.6 10.8 8.3 4.4 7.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) DUF912 PF06024.7 CDI86227.1 - 8.3 6.5 12.4 2.9 8.0 3.1 2.1 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) SRP-alpha_N PF04086.8 CDI86227.1 - 8.6 5.6 19.7 11 5.3 13.6 1.0 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal GDE_N PF12439.3 CDI86227.1 - 10 5.3 9.4 15 4.7 6.5 1.2 1 0 0 1 1 1 0 Glycogen debranching enzyme N terminal Tom22 PF04281.8 CDI86228.1 - 0.075 12.5 1.5 4 6.9 0.1 2.3 1 1 1 2 2 2 0 Mitochondrial import receptor subunit Tom22 PIG-U PF06728.8 CDI86229.1 - 0.022 13.6 6.7 2.4 6.9 0.0 4.2 3 1 0 4 4 4 0 GPI transamidase subunit PIG-U DUF4589 PF15252.1 CDI86230.1 - 2.7 7.7 9.8 0.83 9.4 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4589) Rifin_STEVOR PF02009.11 CDI86230.1 - 4.8 6.7 10.2 0.95 9.0 0.8 2.1 2 0 0 2 2 2 0 Rifin/stevor family Macoilin PF09726.4 CDI86230.1 - 7.4 4.7 16.5 3.7 5.7 3.9 2.0 2 0 0 2 2 2 0 Transmembrane protein SpoIIIAH PF12685.2 CDI86231.1 - 0.16 11.4 24.6 0.21 11.0 17.0 1.1 1 0 0 1 1 1 0 SpoIIIAH-like protein DUF4613 PF15390.1 CDI86231.1 - 0.73 7.9 23.1 0.89 7.6 16.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) DUF533 PF04391.7 CDI86231.1 - 0.81 9.0 22.2 1.3 8.3 2.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF533) RskA PF10099.4 CDI86231.1 - 0.93 9.2 9.6 2 8.1 1.5 2.2 2 0 0 2 2 2 0 Anti-sigma-K factor rskA DUF2782 PF11191.3 CDI86231.1 - 0.95 9.4 9.8 5.9 6.9 2.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2782) CBP4 PF07960.6 CDI86231.1 - 2 8.0 24.7 2.2 7.8 8.2 2.2 2 0 0 2 2 2 0 CBP4 CD20 PF04103.10 CDI86231.1 - 2.3 8.1 14.4 0.31 10.9 3.6 2.1 1 1 1 2 2 2 0 CD20-like family DUF1266 PF06889.6 CDI86231.1 - 2.8 7.6 13.7 1.4 8.6 3.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1266) Fimbrial PF00419.15 CDI86231.1 - 3.4 7.8 13.1 0.22 11.7 4.8 1.8 2 0 0 2 2 2 0 Fimbrial protein U1snRNP70_N PF12220.3 CDI86231.1 - 6.4 7.1 24.6 7.9 6.8 2.7 2.3 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal DUF4483 PF14825.1 CDI86231.1 - 6.4 6.3 22.7 2.5 7.7 6.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4483) CagX PF03524.10 CDI86231.1 - 7.2 5.8 17.7 4 6.6 5.1 2.1 2 0 0 2 2 2 0 Conjugal transfer protein Herpes_DNAp_acc PF04929.7 CDI86231.1 - 7.9 5.3 19.1 66 2.3 13.2 1.9 1 1 0 1 1 1 0 Herpes DNA replication accessory factor SR-25 PF10500.4 CDI86232.1 - 0.0036 16.8 2.2 0.0036 16.8 1.5 4.6 3 1 1 4 4 4 2 Nuclear RNA-splicing-associated protein GEMIN8 PF15348.1 CDI86232.1 - 0.014 15.5 4.0 0.014 15.5 2.8 3.0 3 0 0 3 3 3 0 Gemini of Cajal bodies-associated protein 8 Myosin_head PF00063.16 CDI86233.1 - 9.1e-159 529.6 0.0 1.1e-130 436.7 0.0 2.2 1 1 1 2 2 2 2 Myosin head (motor domain) Zeta_toxin PF06414.7 CDI86233.1 - 0.019 14.0 0.1 0.036 13.1 0.1 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_19 PF13245.1 CDI86233.1 - 0.021 14.5 0.1 0.05 13.3 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain AAA_22 PF13401.1 CDI86233.1 - 0.027 14.6 0.0 0.079 13.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain UPF0079 PF02367.12 CDI86233.1 - 0.036 13.7 0.0 0.086 12.4 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 RNA_helicase PF00910.17 CDI86233.1 - 0.056 13.6 0.1 0.41 10.8 0.0 2.4 2 0 0 2 2 2 0 RNA helicase AAA_16 PF13191.1 CDI86233.1 - 0.08 12.9 0.0 0.19 11.6 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain PRK PF00485.13 CDI86233.1 - 0.11 12.0 0.1 0.2 11.1 0.1 1.4 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family T2SE PF00437.15 CDI86233.1 - 0.11 11.3 0.0 0.27 10.1 0.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_18 PF13238.1 CDI86233.1 - 0.12 12.6 0.0 0.26 11.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 CDI86233.1 - 0.14 13.0 0.0 0.31 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain GTP_EFTU PF00009.22 CDI86234.1 - 3.9e-59 199.2 0.1 5.8e-59 198.6 0.1 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 CDI86234.1 - 1.3e-35 121.5 0.1 4.6e-35 119.7 0.0 2.0 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.19 CDI86234.1 - 1.5e-18 66.4 0.0 3.1e-18 65.4 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.1 CDI86234.1 - 1.2e-14 53.8 0.0 3.4e-14 52.4 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.20 CDI86234.1 - 1.8e-11 43.9 0.0 4.5e-11 42.7 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 CDI86234.1 - 5.8e-05 23.0 0.0 0.00014 21.7 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 CDI86234.1 - 0.074 12.2 0.0 0.15 11.2 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit DUF1345 PF07077.6 CDI86235.1 - 6.2 6.3 7.3 1.7 8.1 2.1 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1345) FAM60A PF15396.1 CDI86236.1 - 0.018 14.8 21.7 0.022 14.5 15.0 1.0 1 0 0 1 1 1 0 Protein Family FAM60A Raftlin PF15250.1 CDI86236.1 - 0.68 8.4 22.8 0.77 8.2 15.8 1.1 1 0 0 1 1 1 0 Raftlin DUF2146 PF10220.4 CDI86236.1 - 0.79 7.6 21.2 0.88 7.4 14.7 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2146) Tim54 PF11711.3 CDI86236.1 - 1.3 7.5 12.7 1.7 7.1 8.8 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 NPR3 PF03666.8 CDI86236.1 - 2.9 6.3 23.6 3.5 6.0 16.4 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Apt1 PF10351.4 CDI86236.1 - 3.2 6.5 16.8 3.7 6.3 11.6 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain CKAP2_C PF15297.1 CDI86236.1 - 3.8 6.2 23.4 4.9 5.8 16.2 1.1 1 0 0 1 1 1 0 Cytoskeleton-associated protein 2 C-terminus GAGA_bind PF06217.7 CDI86236.1 - 4.2 7.2 24.5 5.1 6.9 17.0 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family SAPS PF04499.10 CDI86236.1 - 5.2 5.5 20.8 6 5.3 14.4 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein AUX_IAA PF02309.11 CDI86236.1 - 6.2 6.4 19.7 9.9 5.8 13.6 1.3 1 0 0 1 1 1 0 AUX/IAA family Peptidase_S64 PF08192.6 CDI86236.1 - 9.2 4.4 18.1 9.8 4.3 12.5 1.0 1 0 0 1 1 1 0 Peptidase family S64 SR-25 PF10500.4 CDI86237.1 - 0.00062 19.2 32.1 0.00062 19.2 22.2 2.7 3 0 0 3 3 3 2 Nuclear RNA-splicing-associated protein Spt20 PF12090.3 CDI86237.1 - 0.01 15.2 1.1 0.01 15.2 0.8 2.6 2 1 0 2 2 2 0 Spt20 family DUF3801 PF12687.2 CDI86237.1 - 1.9 8.0 26.6 1.9 8.0 10.6 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3801) BaxI_1 PF12811.2 CDI86237.1 - 4.5 6.3 13.3 9.1 5.3 4.5 2.1 2 0 0 2 2 2 0 Bax inhibitor 1 like PAT1 PF09770.4 CDI86237.1 - 7.2 4.7 51.9 2 6.5 11.7 2.0 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 CW_binding_2 PF04122.7 CDI86238.1 - 0.046 13.9 4.6 0.62 10.3 0.1 2.3 2 0 0 2 2 2 0 Putative cell wall binding repeat 2 MR_MLE_C PF13378.1 CDI86238.1 - 2.8 7.9 5.0 1.6 8.7 0.2 2.2 2 1 0 2 2 2 0 Enolase C-terminal domain-like Jun PF03957.8 CDI86238.1 - 5.1 6.7 19.8 1.8 8.2 0.9 2.2 2 0 0 2 2 2 0 Jun-like transcription factor FHIPEP PF00771.15 CDI86240.1 - 1.7 6.8 22.1 1 7.5 0.5 2.2 2 0 0 2 2 2 0 FHIPEP family Hamartin PF04388.7 CDI86240.1 - 7.5 5.0 22.5 9.2 4.7 15.6 1.1 1 0 0 1 1 1 0 Hamartin protein SR-25 PF10500.4 CDI86241.1 - 0.017 14.6 9.8 0.019 14.4 6.8 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Aminotran_5 PF00266.14 CDI86241.1 - 0.042 12.5 0.1 0.049 12.3 0.0 1.0 1 0 0 1 1 1 0 Aminotransferase class-V MRP-S26 PF14943.1 CDI86241.1 - 0.098 12.2 4.0 0.13 11.7 2.7 1.2 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 CAF-1_p150 PF11600.3 CDI86241.1 - 0.18 11.1 10.6 0.22 10.8 7.3 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal CDK2AP PF09806.4 CDI86241.1 - 0.33 11.1 19.5 0.37 11.0 13.5 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein BNIP3 PF06553.7 CDI86241.1 - 1.7 7.9 9.7 1.9 7.8 6.7 1.2 1 0 0 1 1 1 0 BNIP3 Suf PF05843.9 CDI86241.1 - 2.2 7.9 12.7 2.4 7.8 8.8 1.0 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DOR PF14839.1 CDI86241.1 - 3 7.5 13.7 3.7 7.2 9.5 1.1 1 0 0 1 1 1 0 DOR family Corona_nucleoca PF00937.13 CDI86241.1 - 4.7 6.0 14.3 5.5 5.8 9.9 1.0 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein Serinc PF03348.10 CDI86241.1 - 6.3 5.3 6.5 6.2 5.4 4.5 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) Presenilin PF01080.12 CDI86241.1 - 7.8 5.2 7.3 7.7 5.2 5.1 1.0 1 0 0 1 1 1 0 Presenilin PCI PF01399.22 CDI86242.1 - 4.5e-14 52.6 0.0 6.1e-14 52.2 0.0 1.3 1 0 0 1 1 1 1 PCI domain FimP PF09766.4 CDI86243.1 - 0.013 14.6 6.1 0.014 14.4 4.2 1.0 1 0 0 1 1 1 0 Fms-interacting protein CDC45 PF02724.9 CDI86243.1 - 0.03 12.3 1.1 0.034 12.2 0.7 1.0 1 0 0 1 1 1 0 CDC45-like protein Hep_59 PF07052.6 CDI86243.1 - 0.041 14.2 4.5 0.071 13.4 3.2 1.4 1 0 0 1 1 1 0 Hepatocellular carcinoma-associated antigen 59 Ribosomal_60s PF00428.14 CDI86243.1 - 0.41 11.0 8.5 0.93 9.9 5.9 1.6 1 0 0 1 1 1 0 60s Acidic ribosomal protein DUF2489 PF10675.4 CDI86243.1 - 0.62 9.7 14.0 0.59 9.8 9.2 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2489) Ca_hom_mod PF14798.1 CDI86243.1 - 0.77 8.6 5.8 0.97 8.3 4.0 1.1 1 0 0 1 1 1 0 Calcium homeostasis modulator DUF4557 PF15101.1 CDI86243.1 - 2.1 8.1 7.8 3 7.6 5.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) FPN1 PF06963.7 CDI86244.1 - 0.25 9.6 2.6 0.51 8.6 1.8 1.5 1 0 0 1 1 1 0 Ferroportin1 (FPN1) SR-25 PF10500.4 CDI86244.1 - 3.5 7.0 13.0 0.45 9.9 0.3 2.4 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein RCC1_2 PF13540.1 CDI86245.1 - 0.00013 21.4 3.9 0.022 14.3 0.1 3.9 3 1 1 4 4 4 1 Regulator of chromosome condensation (RCC1) repeat Neur_chan_memb PF02932.11 CDI86245.1 - 0.00014 21.8 3.1 0.00027 20.9 2.2 1.4 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Suf PF05843.9 CDI86245.1 - 0.0014 18.4 24.7 0.021 14.5 1.3 2.3 2 0 0 2 2 2 2 Suppressor of forked protein (Suf) Spore_coat_CotO PF14153.1 CDI86245.1 - 0.0033 16.9 11.2 0.0033 16.9 7.8 2.1 2 0 0 2 2 2 1 Spore coat protein CotO RCC1 PF00415.13 CDI86245.1 - 0.0037 17.4 0.0 1 9.6 0.0 3.1 3 0 0 3 3 2 1 Regulator of chromosome condensation (RCC1) repeat Ycf1 PF05758.7 CDI86245.1 - 0.04 11.6 9.9 0.0098 13.6 0.6 2.0 2 0 0 2 2 2 0 Ycf1 TFIIA PF03153.8 CDI86245.1 - 0.1 12.4 38.1 0.68 9.7 5.9 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit DUF2052 PF09747.4 CDI86245.1 - 0.12 12.2 20.6 0.1 12.5 5.1 2.2 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) CD20 PF04103.10 CDI86245.1 - 0.13 12.1 4.7 1.6 8.6 0.7 2.3 2 0 0 2 2 2 0 CD20-like family PAT1 PF09770.4 CDI86245.1 - 0.15 10.2 54.4 0.55 8.4 8.6 2.1 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 RR_TM4-6 PF06459.7 CDI86245.1 - 0.15 11.9 16.8 0.39 10.5 0.3 2.2 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 MRP-S31 PF15433.1 CDI86245.1 - 0.16 11.3 20.8 0.2 11.0 6.8 2.1 2 0 0 2 2 2 0 Mitochondrial 28S ribosomal protein S31 SAGA-Tad1 PF12767.2 CDI86245.1 - 0.26 10.9 20.6 0.86 9.2 1.4 2.3 2 0 0 2 2 2 0 Transcriptional regulator of RNA polII, SAGA, subunit IncA PF04156.9 CDI86245.1 - 0.3 10.6 36.9 1.4 8.4 15.3 2.3 2 0 0 2 2 2 0 IncA protein DUF1510 PF07423.6 CDI86245.1 - 0.3 10.4 21.3 0.24 10.7 5.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) EPL1 PF10513.4 CDI86245.1 - 1.2 9.4 21.5 3.9 7.6 2.7 2.4 2 0 0 2 2 2 0 Enhancer of polycomb-like DUF2828 PF11443.3 CDI86245.1 - 1.2 7.2 11.9 3.6 5.6 4.5 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF2828) RIC3 PF15361.1 CDI86245.1 - 1.3 9.2 22.4 0.52 10.5 6.9 2.2 2 0 0 2 2 2 0 Resistance to inhibitors of cholinesterase homologue 3 CDC45 PF02724.9 CDI86245.1 - 1.4 6.8 14.0 1.5 6.7 0.8 2.2 2 0 0 2 2 2 0 CDC45-like protein DUF4366 PF14283.1 CDI86245.1 - 1.4 8.2 11.0 5 6.4 1.5 2.6 3 0 0 3 3 2 0 Domain of unknown function (DUF4366) SPX PF03105.14 CDI86245.1 - 1.5 8.5 13.7 0.22 11.2 1.9 2.1 2 0 0 2 2 2 0 SPX domain DDHD PF02862.12 CDI86245.1 - 1.7 8.3 16.3 4.6 6.9 0.9 2.3 2 0 0 2 2 2 0 DDHD domain Serinc PF03348.10 CDI86245.1 - 1.9 7.1 17.8 2.7 6.6 5.8 2.1 2 0 0 2 2 2 0 Serine incorporator (Serinc) AUX_IAA PF02309.11 CDI86245.1 - 1.9 8.1 16.0 5.2 6.7 0.6 2.2 2 0 0 2 2 2 0 AUX/IAA family Peptidase_S15 PF02129.13 CDI86245.1 - 2.4 7.4 17.8 3.6 6.9 2.2 2.3 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) DUF775 PF05603.7 CDI86245.1 - 2.5 7.5 27.5 0.074 12.5 6.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF775) CPSF100_C PF13299.1 CDI86245.1 - 3 8.0 17.0 4 7.5 5.3 2.3 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal eIF-3_zeta PF05091.7 CDI86245.1 - 3.9 5.9 24.5 2.9 6.4 9.1 2.1 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) AAA_23 PF13476.1 CDI86245.1 - 4.1 7.6 29.1 2.1 8.6 1.9 2.2 2 0 0 2 2 2 0 AAA domain FAM60A PF15396.1 CDI86245.1 - 5.3 6.7 16.8 7.9 6.1 0.9 2.2 2 0 0 2 2 2 0 Protein Family FAM60A PH_4 PF15404.1 CDI86245.1 - 5.3 6.5 19.1 4.7 6.7 5.3 2.3 2 0 0 2 2 2 0 Pleckstrin homology domain Presenilin PF01080.12 CDI86245.1 - 5.4 5.7 12.6 6.4 5.4 0.5 2.1 2 0 0 2 2 2 0 Presenilin N6_N4_Mtase PF01555.13 CDI86245.1 - 5.4 6.4 8.6 1.9 7.8 0.4 2.6 2 1 0 2 2 2 0 DNA methylase MSA-2c PF12238.3 CDI86245.1 - 5.5 6.5 14.9 2.5 7.7 1.0 2.5 2 0 0 2 2 2 0 Merozoite surface antigen 2c FLO_LFY PF01698.11 CDI86245.1 - 5.5 5.7 19.2 5.2 5.8 1.7 2.1 2 0 0 2 2 2 0 Floricaula / Leafy protein RNA_pol_Rpc4 PF05132.9 CDI86245.1 - 6.3 6.7 20.1 4 7.4 1.9 2.5 2 0 0 2 2 2 0 RNA polymerase III RPC4 Rhomboid PF01694.17 CDI86246.1 - 1.1e-25 90.3 14.3 2.2e-25 89.3 9.9 1.5 1 0 0 1 1 1 1 Rhomboid family Corona_nucleoca PF00937.13 CDI86247.1 - 1.5 7.6 17.6 1.8 7.3 12.2 1.1 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein Band_3_cyto PF07565.8 CDI86247.1 - 2 7.8 4.5 3.2 7.2 3.1 1.3 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Pex14_N PF04695.8 CDI86247.1 - 7.1 6.6 22.5 0.7 9.9 9.0 2.3 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Rifin_STEVOR PF02009.11 CDI86247.1 - 9.2 5.8 10.6 13 5.2 7.3 1.2 1 0 0 1 1 1 0 Rifin/stevor family Rad54_N PF08658.5 CDI86248.1 - 0.076 12.7 8.9 0.1 12.3 6.2 1.3 1 0 0 1 1 1 0 Rad54 N terminal Pox_Ag35 PF03286.9 CDI86248.1 - 0.6 9.6 18.2 0.69 9.4 12.6 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Daxx PF03344.10 CDI86248.1 - 0.67 8.3 26.5 0.78 8.1 18.4 1.0 1 0 0 1 1 1 0 Daxx Family DUF1675 PF07897.6 CDI86248.1 - 1.3 8.7 12.8 1.6 8.5 8.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) SprA-related PF12118.3 CDI86248.1 - 1.5 8.0 42.8 1.9 7.7 29.7 1.2 1 0 0 1 1 1 0 SprA-related family RR_TM4-6 PF06459.7 CDI86248.1 - 3.1 7.6 23.9 3.5 7.4 16.6 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF1510 PF07423.6 CDI86248.1 - 3.4 6.9 27.7 4.3 6.6 19.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Med15 PF09606.5 CDI86248.1 - 3.9 5.5 51.7 4.3 5.4 35.8 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal eIF3_subunit PF08597.5 CDI86248.1 - 4.1 6.9 24.6 4.9 6.6 17.0 1.2 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit Band_3_cyto PF07565.8 CDI86248.1 - 4.9 6.5 16.9 7 6.0 11.7 1.4 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Ycf1 PF05758.7 CDI86248.1 - 5.5 4.5 25.5 5.8 4.4 17.7 1.0 1 0 0 1 1 1 0 Ycf1 SAGA-Tad1 PF12767.2 CDI86248.1 - 6.3 6.3 23.4 7 6.2 16.2 1.1 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit Plasmodium_Vir PF05795.6 CDI86248.1 - 6.5 5.8 10.3 9.5 5.3 7.1 1.3 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Merozoite_SPAM PF07133.6 CDI86248.1 - 6.5 6.6 23.1 8.2 6.2 16.0 1.1 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) Zip PF02535.17 CDI86248.1 - 6.5 5.6 10.8 8.3 5.3 7.5 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter DUF4045 PF13254.1 CDI86248.1 - 7.1 5.8 21.7 7.6 5.6 15.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) APG6 PF04111.7 CDI86248.1 - 7.5 5.4 27.0 8.3 5.3 18.7 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 Peptidase_S15 PF02129.13 CDI86248.1 - 7.6 5.8 16.0 10 5.4 11.1 1.3 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Rtf2 PF04641.7 CDI86248.1 - 7.9 5.5 24.6 8.8 5.4 17.1 1.0 1 0 0 1 1 1 0 Rtf2 RING-finger DUF4175 PF13779.1 CDI86248.1 - 8.6 3.9 49.1 9.4 3.7 34.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Gag_spuma PF03276.9 CDI86248.1 - 8.7 4.5 32.5 10 4.2 22.5 1.1 1 0 0 1 1 1 0 Spumavirus gag protein Parvo_coat PF00740.13 CDI86248.1 - 8.8 5.1 24.4 8.9 5.1 16.9 1.0 1 0 0 1 1 1 0 Parvovirus coat protein VP2 Asp-B-Hydro_N PF05279.6 CDI86248.1 - 9.5 5.9 23.2 12 5.7 16.1 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region PRA1 PF03208.14 CDI86249.1 - 0.037 13.3 0.1 0.096 12.0 0.1 1.7 1 0 0 1 1 1 0 PRA1 family protein DUF3357 PF11837.3 CDI86249.1 - 0.041 13.7 10.4 0.54 10.1 0.1 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF3357) BPD_transp_2 PF02653.11 CDI86249.1 - 0.063 12.2 2.1 0.05 12.5 0.2 1.7 2 0 0 2 2 2 0 Branched-chain amino acid transport system / permease component DUF1345 PF07077.6 CDI86249.1 - 1.2 8.5 9.8 0.22 11.0 0.8 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1345) DUF4647 PF15504.1 CDI86249.1 - 1.3 7.8 19.9 0.26 10.1 5.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4647) Presenilin PF01080.12 CDI86249.1 - 1.9 7.1 15.1 1.9 7.2 3.8 2.1 2 0 0 2 2 2 0 Presenilin Pox_Ag35 PF03286.9 CDI86250.1 - 1.6 8.1 16.6 1.7 8.1 11.5 1.0 1 0 0 1 1 1 0 Pox virus Ag35 surface protein FYDLN_acid PF09538.5 CDI86250.1 - 1.8 9.1 13.7 1.8 9.1 9.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) AIF_C PF14721.1 CDI86250.1 - 2.1 8.6 17.4 2.2 8.5 12.1 1.1 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term CobT PF06213.7 CDI86250.1 - 2.5 7.1 22.2 2.7 7.0 15.4 1.0 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF1510 PF07423.6 CDI86250.1 - 3.8 6.8 24.7 4 6.7 17.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) FAM176 PF14851.1 CDI86250.1 - 4.4 6.9 14.3 6 6.5 9.9 1.3 1 0 0 1 1 1 0 FAM176 family Ctr PF04145.10 CDI86250.1 - 6.8 6.7 12.5 8.6 6.3 8.7 1.2 1 0 0 1 1 1 0 Ctr copper transporter family Spore_coat_CotO PF14153.1 CDI86250.1 - 7 6.0 31.7 7.6 5.9 22.0 1.0 1 0 0 1 1 1 0 Spore coat protein CotO DDHD PF02862.12 CDI86250.1 - 7.4 6.2 21.9 7.8 6.2 15.2 1.0 1 0 0 1 1 1 0 DDHD domain XRCC4 PF06632.7 CDI86250.1 - 8 5.2 17.0 8.4 5.1 11.8 1.1 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 DUF1764 PF08576.5 CDI86250.1 - 8.1 7.2 23.1 11 6.8 16.0 1.3 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) TRAP_alpha PF03896.11 CDI86250.1 - 8.2 5.3 12.0 8.5 5.2 8.3 1.0 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Paf1 PF03985.8 CDI86250.1 - 8.4 5.0 27.2 8.2 5.0 18.9 1.0 1 0 0 1 1 1 0 Paf1 DUF702 PF05142.7 CDI86250.1 - 9.1 6.4 19.3 10 6.2 13.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF702) DUF4355 PF14265.1 CDI86250.1 - 9.2 6.2 32.2 10 6.0 22.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4355) Effector_1 PF04518.7 CDI86251.1 - 0.044 12.7 15.7 0.056 12.4 10.9 1.1 1 0 0 1 1 1 0 Effector from type III secretion system PLRV_ORF5 PF01690.12 CDI86251.1 - 1.1 8.2 11.5 1.3 8.0 8.0 1.0 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein SOBP PF15279.1 CDI86251.1 - 1.7 8.9 6.4 2.3 8.5 4.4 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein Med15 PF09606.5 CDI86251.1 - 1.8 6.6 32.6 2.3 6.3 22.6 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal GTPase_Cys_C PF12631.2 CDI86251.1 - 4.8 7.6 11.9 7.9 6.9 6.5 2.6 1 1 1 2 2 2 0 Catalytic cysteine-containing C-terminus of GTPase, MnmE PAT1 PF09770.4 CDI86251.1 - 5.3 5.1 27.7 6.4 4.8 19.2 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Med15 PF09606.5 CDI86252.1 - 2.2 6.3 23.5 2.6 6.1 16.3 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Ribosomal_60s PF00428.14 CDI86253.1 - 0.0078 16.5 3.7 0.0078 16.5 2.5 5.2 4 1 0 4 4 4 2 60s Acidic ribosomal protein Trehalase PF01204.13 CDI86256.1 - 1.2e-29 103.4 0.0 1.5e-29 103.0 0.0 1.1 1 0 0 1 1 1 1 Trehalase DHODB_Fe-S_bind PF10418.4 CDI86256.1 - 0.092 12.2 0.0 0.24 10.9 0.0 1.7 1 0 0 1 1 1 0 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B PP2C PF00481.16 CDI86257.1 - 5.4e-18 65.3 0.1 4.8e-16 58.9 0.0 2.0 1 1 1 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.1 CDI86257.1 - 0.00038 19.9 0.0 0.0034 16.8 0.0 2.0 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 CDI86257.1 - 0.006 16.2 0.0 0.18 11.5 0.0 2.4 1 1 1 2 2 2 1 Stage II sporulation protein E (SpoIIE) CSD PF00313.17 CDI86259.1 - 5.6e-24 83.6 0.3 9.9e-24 82.9 0.2 1.4 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain OB_RNB PF08206.6 CDI86259.1 - 0.0019 17.6 0.1 0.0039 16.6 0.1 1.4 1 0 0 1 1 1 1 Ribonuclease B OB domain Prenyltrans PF00432.16 CDI86260.1 - 3.8e-20 71.1 27.8 4.2e-08 32.6 0.1 7.6 8 0 0 8 8 8 6 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 CDI86260.1 - 1e-14 54.9 0.1 2.2e-07 31.2 0.0 5.4 4 2 2 6 6 6 4 Prenyltransferase-like Rpr2 PF04032.11 CDI86260.1 - 0.044 13.6 0.0 0.22 11.4 0.0 2.1 2 0 0 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain Pkinase PF00069.20 CDI86261.1 - 3.6e-60 203.2 1.1 3.8e-60 203.2 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDI86261.1 - 4.1e-35 121.0 0.0 7.1e-35 120.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase DUF2721 PF11026.3 CDI86262.1 - 0.034 13.7 0.4 0.091 12.3 0.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2721) UPF0113 PF03657.8 CDI86263.1 - 2.8e-10 40.1 0.0 3.9e-10 39.6 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0113) MMR_HSR1 PF01926.18 CDI86264.1 - 6.5e-38 129.2 0.0 4.5e-19 68.5 0.0 2.4 2 0 0 2 2 2 2 50S ribosome-binding GTPase KH_dom-like PF14714.1 CDI86264.1 - 4.1e-26 90.7 0.1 1.4e-25 89.0 0.1 1.9 2 0 0 2 2 2 1 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal FeoB_N PF02421.13 CDI86264.1 - 6.1e-17 61.3 0.0 1e-09 37.8 0.0 3.8 3 1 0 3 3 3 2 Ferrous iron transport protein B AIG1 PF04548.11 CDI86264.1 - 4.2e-13 48.9 0.0 1.8e-05 23.9 0.0 2.6 2 1 0 2 2 2 2 AIG1 family Dynamin_N PF00350.18 CDI86264.1 - 1.6e-12 47.5 0.3 0.00057 19.7 0.1 4.2 3 1 1 4 4 4 2 Dynamin family GTP_EFTU PF00009.22 CDI86264.1 - 2e-12 46.9 0.4 2e-06 27.3 0.1 5.4 2 2 0 2 2 2 2 Elongation factor Tu GTP binding domain Miro PF08477.8 CDI86264.1 - 1.6e-09 38.2 0.0 7.5e-05 23.2 0.0 3.0 3 1 0 3 3 2 2 Miro-like protein DUF258 PF03193.11 CDI86264.1 - 6.3e-07 28.7 0.0 0.046 12.9 0.0 2.9 2 1 0 2 2 2 2 Protein of unknown function, DUF258 Gtr1_RagA PF04670.7 CDI86264.1 - 1.4e-06 27.6 0.0 0.028 13.5 0.0 2.3 2 1 0 2 2 2 2 Gtr1/RagA G protein conserved region Ras PF00071.17 CDI86264.1 - 4.4e-06 26.1 0.1 0.019 14.3 0.0 3.3 3 1 0 3 3 3 2 Ras family Arf PF00025.16 CDI86264.1 - 0.00083 18.6 0.2 0.007 15.6 0.1 2.6 2 1 0 2 2 2 1 ADP-ribosylation factor family cobW PF02492.14 CDI86264.1 - 0.00097 18.6 0.2 6 6.2 0.0 3.2 3 0 0 3 3 3 1 CobW/HypB/UreG, nucleotide-binding domain MobB PF03205.9 CDI86264.1 - 0.0043 16.7 0.0 2.3 7.9 0.0 2.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B ABC_tran PF00005.22 CDI86264.1 - 0.0068 16.7 0.0 2.1 8.6 0.0 3.2 3 0 0 3 3 3 1 ABC transporter PduV-EutP PF10662.4 CDI86264.1 - 0.014 14.9 0.0 7.5 6.0 0.0 4.2 5 0 0 5 5 5 0 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.5 CDI86264.1 - 0.022 13.9 0.0 1.7 7.8 0.0 2.8 2 1 1 3 3 3 0 Signal recognition particle receptor beta subunit AAA_22 PF13401.1 CDI86264.1 - 0.035 14.2 0.0 9.1 6.4 0.0 3.1 2 1 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 CDI86264.1 - 0.077 12.6 0.0 4.8 6.8 0.0 2.3 2 0 0 2 2 2 0 Archaeal ATPase DEAD PF00270.24 CDI86265.1 - 5.8e-42 143.0 0.1 7.5e-42 142.6 0.0 1.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 CDI86265.1 - 0.0003 20.6 0.0 0.0079 16.0 0.0 2.2 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 CDI86265.1 - 0.028 14.2 0.0 0.055 13.3 0.0 1.5 1 0 0 1 1 1 0 Helicase conserved C-terminal domain DUF1811 PF08838.5 CDI86265.1 - 0.041 13.8 0.0 0.11 12.4 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1811) CMS1 PF14617.1 CDI86265.1 - 0.13 11.3 0.1 0.22 10.5 0.0 1.4 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit NUDIX PF00293.23 CDI86266.1 - 0.01 15.5 0.0 0.017 14.7 0.0 1.3 1 0 0 1 1 1 0 NUDIX domain BRF1 PF07741.8 CDI86266.1 - 0.021 15.0 2.9 0.05 13.8 2.0 1.6 1 0 0 1 1 1 0 Brf1-like TBP-binding domain DUF2975 PF11188.3 CDI86266.1 - 0.045 13.4 0.0 0.23 11.1 0.0 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2975) MRP-L46 PF11788.3 CDI86266.1 - 1.2 9.7 10.6 4.3 8.0 5.6 2.3 1 1 1 2 2 2 0 39S mitochondrial ribosomal protein L46 LSM PF01423.17 CDI86267.1 - 4.2e-18 64.6 0.0 5.3e-18 64.3 0.0 1.1 1 0 0 1 1 1 1 LSM domain Clathrin PF00637.15 CDI86270.1 - 6.6e-176 576.9 22.6 3.6e-30 104.4 0.4 7.8 8 0 0 8 8 8 7 Region in Clathrin and VPS Clathrin_H_link PF13838.1 CDI86270.1 - 3.6e-26 90.8 0.2 3.7e-25 87.6 0.0 2.7 2 0 0 2 2 2 1 Clathrin-H-link Coatomer_WDAD PF04053.9 CDI86270.1 - 4.5e-08 32.3 1.2 0.13 11.0 0.0 3.8 3 0 0 3 3 3 3 Coatomer WD associated region Clathrin_propel PF01394.15 CDI86270.1 - 2e-07 30.8 0.0 7.8e-05 22.7 0.0 4.0 5 0 0 5 5 5 1 Clathrin propeller repeat TPR_17 PF13431.1 CDI86270.1 - 0.039 14.1 0.2 6.7 7.1 0.0 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF1269 PF06897.7 CDI86270.1 - 0.099 12.6 0.4 16 5.6 0.0 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1269) TPR_14 PF13428.1 CDI86270.1 - 0.1 13.2 28.6 5.9 7.8 0.0 11.0 12 1 1 13 13 13 0 Tetratricopeptide repeat TPR_1 PF00515.23 CDI86270.1 - 0.13 11.9 9.3 16 5.2 0.0 5.8 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_2 PF07719.12 CDI86270.1 - 0.19 11.7 18.1 0.57 10.2 0.0 6.8 7 0 0 7 7 7 0 Tetratricopeptide repeat Peptidase_S8 PF00082.17 CDI86272.1 - 1.9e-43 148.6 6.7 3.7e-43 147.7 4.7 1.5 1 0 0 1 1 1 1 Subtilase family CbiN PF02553.10 CDI86272.1 - 0.2 11.6 1.3 6.2 6.8 0.2 3.0 3 0 0 3 3 3 0 Cobalt transport protein component CbiN DUF3408 PF11888.3 CDI86272.1 - 5.4 6.9 6.0 3.3 7.6 1.7 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3408) DUF3357 PF11837.3 CDI86273.1 - 0.0016 18.2 4.9 0.55 10.1 0.2 4.7 4 1 1 5 5 5 1 Domain of unknown function (DUF3357) DUF2244 PF10003.4 CDI86273.1 - 1 8.7 0.0 1 8.7 0.0 4.0 7 0 0 7 7 7 0 Integral membrane protein (DUF2244) Sec20 PF03908.8 CDI86274.1 - 3.9e-14 52.0 0.2 2.1e-13 49.7 0.2 2.3 1 0 0 1 1 1 1 Sec20 NCD2 PF04905.8 CDI86274.1 - 0.073 12.8 0.1 0.073 12.8 0.1 2.9 3 0 0 3 3 3 0 NAB conserved region 2 (NCD2) TMF_DNA_bd PF12329.3 CDI86274.1 - 0.86 9.4 6.6 0.5 10.2 1.9 2.4 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Scm3 PF10384.4 CDI86274.1 - 1.1 8.7 6.0 0.93 9.0 0.1 2.9 3 0 0 3 3 3 0 Centromere protein Scm3 HupE_UreJ_2 PF13795.1 CDI86274.1 - 2.8 7.4 6.3 0.63 9.5 1.5 1.9 2 0 0 2 2 2 0 HupE / UreJ protein T2SF PF00482.18 CDI86274.1 - 2.9 7.8 7.8 18 5.2 0.1 3.7 4 1 1 5 5 5 0 Type II secretion system (T2SS), protein F DUF342 PF03961.8 CDI86274.1 - 9.6 4.4 7.1 4.3 5.6 0.4 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF342) ABC2_membrane PF01061.19 CDI86275.1 - 4.1e-24 84.9 9.9 8.2e-23 80.6 8.1 2.2 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.22 CDI86275.1 - 1.6e-21 77.0 0.1 2.6e-21 76.3 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 CDI86275.1 - 6.3e-09 36.2 0.3 4.1e-05 23.7 0.0 2.2 1 1 0 2 2 2 2 AAA domain DUF258 PF03193.11 CDI86275.1 - 6.2e-05 22.2 0.1 0.00011 21.4 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 CDI86275.1 - 0.00018 21.5 0.2 0.00042 20.3 0.1 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.1 CDI86275.1 - 0.00022 20.7 0.3 0.0005 19.5 0.2 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_25 PF13481.1 CDI86275.1 - 0.0011 18.3 0.1 0.0027 17.1 0.1 1.6 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.18 CDI86275.1 - 0.0086 16.0 0.0 0.015 15.2 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_18 PF13238.1 CDI86275.1 - 0.0088 16.3 0.0 0.022 15.0 0.0 1.7 2 0 0 2 2 1 1 AAA domain DUF87 PF01935.12 CDI86275.1 - 0.0096 15.7 0.5 0.02 14.7 0.3 1.4 1 0 0 1 1 1 1 Domain of unknown function DUF87 AAA_17 PF13207.1 CDI86275.1 - 0.012 16.4 0.0 0.021 15.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain ArgK PF03308.11 CDI86275.1 - 0.022 13.5 0.2 0.051 12.3 0.2 1.5 1 0 0 1 1 1 0 ArgK protein AAA_28 PF13521.1 CDI86275.1 - 0.038 13.9 0.0 0.068 13.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain Pox_A9 PF04835.7 CDI86275.1 - 0.067 13.0 0.6 0.47 10.3 0.2 2.2 2 0 0 2 2 2 0 A9 protein conserved region AAA_22 PF13401.1 CDI86275.1 - 0.072 13.2 0.1 0.23 11.5 0.1 1.9 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.1 CDI86275.1 - 0.091 12.3 0.2 0.17 11.4 0.1 1.4 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 CDI86275.1 - 0.094 12.1 0.0 0.23 10.8 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein UPF0079 PF02367.12 CDI86275.1 - 0.13 11.9 0.3 0.25 10.9 0.2 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_15 PF13175.1 CDI86275.1 - 0.13 11.2 0.0 0.57 9.1 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain T2SE PF00437.15 CDI86275.1 - 0.17 10.7 0.0 0.29 10.0 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_10 PF12846.2 CDI86275.1 - 0.2 11.0 0.9 0.37 10.1 0.6 1.3 1 0 0 1 1 1 0 AAA-like domain SseC PF04888.7 CDI86278.1 - 3.8e-05 23.1 20.2 3.8e-05 23.1 14.0 2.0 2 0 0 2 2 1 1 Secretion system effector C (SseC) like family IncA PF04156.9 CDI86278.1 - 0.00025 20.6 3.0 0.00025 20.6 2.1 2.3 2 1 0 2 2 1 1 IncA protein BatD PF13584.1 CDI86278.1 - 0.0073 14.9 9.6 0.12 10.9 3.1 2.0 1 1 0 2 2 2 2 Oxygen tolerance Apc15p PF05841.6 CDI86278.1 - 0.012 16.3 4.0 0.012 16.3 2.8 2.1 2 0 0 2 2 2 0 Apc15p protein Gti1_Pac2 PF09729.4 CDI86278.1 - 0.019 14.8 6.9 0.15 11.9 0.6 2.0 2 0 0 2 2 2 0 Gti1/Pac2 family FAM176 PF14851.1 CDI86278.1 - 0.021 14.4 5.1 0.56 9.8 1.4 2.1 2 0 0 2 2 2 0 FAM176 family DUF3357 PF11837.3 CDI86278.1 - 0.029 14.1 7.3 0.074 12.8 0.2 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF3357) RNA_pol_Rpb1_5 PF04998.12 CDI86278.1 - 0.044 13.0 1.4 0.058 12.6 1.0 1.2 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 Spt20 PF12090.3 CDI86278.1 - 0.058 12.7 21.2 0.21 10.9 1.1 2.3 2 0 0 2 2 2 0 Spt20 family Glt_symporter PF03616.9 CDI86278.1 - 0.078 11.4 7.2 0.86 8.0 0.1 2.1 2 0 0 2 2 2 0 Sodium/glutamate symporter EphA2_TM PF14575.1 CDI86278.1 - 0.089 13.2 0.5 0.089 13.2 0.4 2.7 2 1 0 2 2 1 0 Ephrin type-A receptor 2 transmembrane domain HD-ZIP_N PF04618.7 CDI86278.1 - 0.28 11.7 10.3 0.85 10.1 3.1 2.2 2 0 0 2 2 2 0 HD-ZIP protein N terminus RSN1_TM PF13967.1 CDI86278.1 - 0.41 10.2 2.2 2.3 7.7 0.0 2.4 2 1 0 2 2 2 0 Late exocytosis, associated with Golgi transport OATP PF03137.15 CDI86278.1 - 0.54 8.2 11.4 2.5 6.0 4.3 2.1 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Conotoxin PF02950.12 CDI86278.1 - 0.55 11.0 15.7 1.2 9.9 1.5 2.5 2 0 0 2 2 2 0 Conotoxin GRP PF07172.6 CDI86278.1 - 0.55 10.7 7.5 0.92 10.0 0.1 2.3 2 0 0 2 2 2 0 Glycine rich protein family AUX_IAA PF02309.11 CDI86278.1 - 0.61 9.7 10.3 3.5 7.3 4.3 2.1 2 0 0 2 2 2 0 AUX/IAA family Peroxin-13_N PF04088.8 CDI86278.1 - 0.72 9.7 11.5 2.7 7.9 2.9 2.1 2 0 0 2 2 2 0 Peroxin 13, N-terminal region DUF4094 PF13334.1 CDI86278.1 - 0.8 10.1 17.9 2.9 8.3 0.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4094) HNOBA PF07701.9 CDI86278.1 - 0.83 8.8 12.3 3 7.0 0.3 2.1 2 0 0 2 2 2 0 Heme NO binding associated DUF808 PF05661.7 CDI86278.1 - 0.86 8.3 9.9 1.6 7.4 2.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF808) TMEM51 PF15345.1 CDI86278.1 - 0.97 9.0 19.9 0.53 9.9 0.2 2.1 2 0 0 2 2 2 0 Transmembrane protein 51 Nucleoside_tran PF01733.13 CDI86278.1 - 1.1 8.4 11.6 0.25 10.4 0.2 2.0 1 1 1 2 2 2 0 Nucleoside transporter FPN1 PF06963.7 CDI86278.1 - 1.1 7.5 9.1 1.6 7.0 0.1 2.1 2 0 0 2 2 2 0 Ferroportin1 (FPN1) DUF3278 PF11683.3 CDI86278.1 - 1.2 9.1 4.9 1.7 8.6 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3278) Zn_peptidase PF04228.8 CDI86278.1 - 1.2 8.2 17.6 0.2 10.8 0.5 2.1 2 0 0 2 2 2 0 Putative neutral zinc metallopeptidase Peptidase_S49_N PF08496.5 CDI86278.1 - 1.5 8.6 16.5 2.6 7.8 0.3 2.2 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Methyltransf_23 PF13489.1 CDI86278.1 - 1.8 8.2 7.0 2.5 7.8 1.3 2.2 2 0 0 2 2 2 0 Methyltransferase domain Serinc PF03348.10 CDI86278.1 - 2.2 6.8 15.5 3 6.4 0.3 2.1 2 0 0 2 2 2 0 Serine incorporator (Serinc) Dala_Dala_lig_N PF01820.16 CDI86278.1 - 2.5 8.4 11.0 1.9 8.8 2.3 2.1 2 0 0 2 2 2 0 D-ala D-ala ligase N-terminus Neur_chan_memb PF02932.11 CDI86278.1 - 2.7 7.8 12.2 3.7 7.3 8.5 1.3 1 1 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Velvet PF11754.3 CDI86278.1 - 2.7 7.5 11.0 5.2 6.6 0.5 2.1 2 0 0 2 2 2 0 Velvet factor FimP PF09766.4 CDI86278.1 - 3.3 6.6 37.7 1.6 7.7 14.4 2.0 2 0 0 2 2 2 0 Fms-interacting protein 7tm_1 PF00001.16 CDI86278.1 - 4.7 6.2 11.2 0.94 8.5 0.4 2.1 1 1 0 2 2 2 0 7 transmembrane receptor (rhodopsin family) OSTbeta PF15048.1 CDI86278.1 - 5.4 7.1 11.4 9 6.3 0.1 2.2 2 0 0 2 2 2 0 Organic solute transporter subunit beta protein FLO_LFY PF01698.11 CDI86278.1 - 6 5.6 14.7 0.67 8.7 3.5 2.1 2 0 0 2 2 2 0 Floricaula / Leafy protein Afi1 PF07792.7 CDI86278.1 - 6 6.8 17.2 0.29 11.1 3.0 2.1 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking DUF3464 PF11947.3 CDI86278.1 - 6.1 6.2 14.4 0.15 11.5 1.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3464) SHR3_chaperone PF08229.6 CDI86278.1 - 7.5 5.4 24.6 0.74 8.7 1.5 2.2 2 0 0 2 2 2 0 ER membrane protein SH3 IncFII_repA PF02387.10 CDI86278.1 - 7.6 5.6 16.3 0.14 11.2 0.6 2.1 2 0 0 2 2 2 0 IncFII RepA protein family Anoctamin PF04547.7 CDI86278.1 - 7.7 5.0 10.0 10 4.6 3.3 2.1 2 0 0 2 2 2 0 Calcium-activated chloride channel DUF3347 PF11827.3 CDI86278.1 - 8.4 6.3 20.8 0.52 10.2 5.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3347) DcuC PF03606.10 CDI86278.1 - 8.6 4.4 15.9 0.11 10.7 1.5 2.0 2 0 0 2 2 2 0 C4-dicarboxylate anaerobic carrier CRF1 PF10380.4 CDI86278.1 - 8.8 6.6 12.5 6.5 7.1 4.0 2.1 2 0 0 2 2 2 0 Transcription factor CRF1 Hom_end_hint PF05203.11 CDI86278.1 - 9.2 5.9 13.0 9.6 5.8 4.5 2.1 2 0 0 2 2 2 0 Hom_end-associated Hint CD20 PF04103.10 CDI86278.1 - 9.6 6.1 15.5 0.81 9.6 0.6 2.2 1 1 1 2 2 2 0 CD20-like family DUF4557 PF15101.1 CDI86278.1 - 9.6 5.9 35.4 6 6.6 4.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4557) Ribosomal_60s PF00428.14 CDI86279.1 - 0.01 16.2 2.1 0.01 16.2 1.5 2.7 3 0 0 3 3 3 0 60s Acidic ribosomal protein CENP-T PF15511.1 CDI86279.1 - 0.13 11.4 32.7 0.26 10.4 22.7 1.4 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Herpes_DNAp_acc PF04929.7 CDI86279.1 - 1 8.2 24.6 0.014 14.4 7.8 2.2 1 1 1 2 2 2 0 Herpes DNA replication accessory factor Herpes_UL87 PF03043.9 CDI86279.1 - 4.5 5.5 24.4 5.9 5.1 16.9 1.1 1 0 0 1 1 1 0 Herpesvirus UL87 family SpoIIIAH PF12685.2 CDI86279.1 - 5.2 6.5 37.6 1.2 8.5 5.7 2.6 3 0 0 3 3 3 0 SpoIIIAH-like protein DUF1183 PF06682.7 CDI86279.1 - 7 6.1 27.7 0.25 10.8 10.9 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1183) DUF4366 PF14283.1 CDI86280.1 - 0.17 11.2 10.2 0.18 11.2 7.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) Serinc PF03348.10 CDI86280.1 - 0.88 8.2 18.1 0.87 8.2 12.6 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) DDRGK PF09756.4 CDI86280.1 - 1.4 8.3 27.1 1.5 8.2 18.8 1.1 1 0 0 1 1 1 0 DDRGK domain RIC3 PF15361.1 CDI86280.1 - 2.4 8.3 18.3 3 8.0 12.7 1.1 1 0 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 FAM176 PF14851.1 CDI86280.1 - 2.5 7.7 13.5 2.9 7.5 9.3 1.2 1 0 0 1 1 1 0 FAM176 family DUF2828 PF11443.3 CDI86280.1 - 2.6 6.1 17.8 2.8 6.0 12.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) PBP1_TM PF14812.1 CDI86280.1 - 2.8 8.3 12.9 3.5 7.9 8.9 1.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal PAT1 PF09770.4 CDI86280.1 - 2.9 6.0 39.8 3 5.9 27.6 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 FYDLN_acid PF09538.5 CDI86280.1 - 3 8.4 13.3 3.8 8.1 9.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) NARP1 PF12569.3 CDI86280.1 - 3.1 6.4 22.4 3.4 6.3 15.5 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Pex14_N PF04695.8 CDI86280.1 - 3.3 7.7 26.3 4.4 7.3 18.2 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Pox_Ag35 PF03286.9 CDI86280.1 - 3.4 7.1 16.0 4 6.9 11.1 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein P5-ATPase PF12409.3 CDI86280.1 - 3.7 7.4 14.5 4.1 7.2 10.0 1.1 1 0 0 1 1 1 0 P5-type ATPase cation transporter DUF3306 PF11748.3 CDI86280.1 - 3.8 8.2 18.5 5.6 7.6 12.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3306) MDFI PF15316.1 CDI86280.1 - 4.2 7.3 11.0 5.1 7.0 7.6 1.2 1 0 0 1 1 1 0 MyoD family inhibitor Bud13 PF09736.4 CDI86280.1 - 4.2 7.6 25.9 4.8 7.4 17.9 1.1 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex Pap_E4 PF02711.9 CDI86280.1 - 4.3 8.2 16.8 5.6 7.8 11.6 1.2 1 0 0 1 1 1 0 E4 protein Plasmodium_Vir PF05795.6 CDI86280.1 - 4.8 6.2 12.1 5.2 6.1 8.4 1.0 1 0 0 1 1 1 0 Plasmodium vivax Vir protein AIF_C PF14721.1 CDI86280.1 - 4.9 7.4 17.5 6.2 7.0 12.1 1.2 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Gti1_Pac2 PF09729.4 CDI86280.1 - 5.1 6.9 16.7 6.1 6.6 11.5 1.1 1 0 0 1 1 1 0 Gti1/Pac2 family Rtf2 PF04641.7 CDI86280.1 - 5.1 6.2 21.8 5.6 6.0 15.1 1.0 1 0 0 1 1 1 0 Rtf2 RING-finger RR_TM4-6 PF06459.7 CDI86280.1 - 5.8 6.7 22.0 5.8 6.7 15.2 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SelP_N PF04592.9 CDI86280.1 - 6.5 6.0 21.3 7.2 5.9 14.7 1.0 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Dynamin_N PF00350.18 CDI86280.1 - 7.3 6.3 12.7 9.5 6.0 8.8 1.2 1 0 0 1 1 1 0 Dynamin family DUF702 PF05142.7 CDI86280.1 - 7.7 6.6 18.2 8.5 6.5 12.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF702) YABBY PF04690.8 CDI86280.1 - 8 6.6 14.6 8.9 6.5 10.1 1.1 1 0 0 1 1 1 0 YABBY protein Zip PF02535.17 CDI86280.1 - 8.6 5.2 14.5 8.5 5.2 10.1 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter CKAP2_C PF15297.1 CDI86280.1 - 8.6 5.0 22.8 9.9 4.8 15.8 1.0 1 0 0 1 1 1 0 Cytoskeleton-associated protein 2 C-terminus AUX_IAA PF02309.11 CDI86280.1 - 8.9 5.9 18.1 10 5.7 12.6 1.1 1 0 0 1 1 1 0 AUX/IAA family MSA-2c PF12238.3 CDI86280.1 - 9 5.8 18.0 9.8 5.7 12.5 1.1 1 0 0 1 1 1 0 Merozoite surface antigen 2c DUF1510 PF07423.6 CDI86280.1 - 9.2 5.5 26.4 10 5.4 18.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) eIF-3_zeta PF05091.7 CDI86280.1 - 9.3 4.7 25.4 10 4.5 17.6 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Ctr PF04145.10 CDI86280.1 - 9.7 6.2 13.2 12 5.8 9.1 1.3 1 0 0 1 1 1 0 Ctr copper transporter family Lactate_perm PF02652.9 CDI86282.1 - 0.047 12.1 1.1 0.064 11.7 0.8 1.1 1 0 0 1 1 1 0 L-lactate permease DUF3526 PF12040.3 CDI86282.1 - 0.049 13.7 21.5 0.22 11.6 5.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3526) BaxI_1 PF12811.2 CDI86282.1 - 0.3 10.2 11.4 0.064 12.4 0.9 2.1 2 0 0 2 2 2 0 Bax inhibitor 1 like DUF4407 PF14362.1 CDI86282.1 - 0.88 8.4 13.4 1.7 7.5 9.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) PAT1 PF09770.4 CDI86282.1 - 3.3 5.8 46.8 2.4 6.3 9.6 2.0 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 DUF2887 PF11103.3 CDI86282.1 - 4.4 6.8 24.6 0.61 9.6 4.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2887) Ribosomal_60s PF00428.14 CDI86283.1 - 9 6.7 60.3 0.16 12.3 16.2 5.3 4 1 0 4 4 4 0 60s Acidic ribosomal protein DDHD PF02862.12 CDI86286.1 - 0.087 12.6 1.5 0.1 12.3 1.1 1.1 1 0 0 1 1 1 0 DDHD domain U1snRNP70_N PF12220.3 CDI86286.1 - 2.1 8.7 13.6 0.69 10.2 0.5 2.2 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal ATAD4 PF15321.1 CDI86286.1 - 2.4 9.1 8.1 11 7.0 0.6 2.1 2 0 0 2 2 2 0 ATPase family AAA domain containing 4 FimP PF09766.4 CDI86286.1 - 4 6.4 21.6 0.44 9.5 2.7 2.0 2 0 0 2 2 2 0 Fms-interacting protein Suf PF05843.9 CDI86286.1 - 9.4 5.8 16.9 5 6.7 2.9 2.0 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) ETRAMP PF09716.5 CDI86288.1 - 1.4 8.9 0.0 1.4 8.9 0.0 4.5 5 2 0 5 5 5 0 Malarial early transcribed membrane protein (ETRAMP) Herpes_UL87 PF03043.9 CDI86288.1 - 7 4.9 44.0 3 6.1 13.7 2.1 1 1 1 2 2 2 0 Herpesvirus UL87 family DUF2232 PF09991.4 CDI86289.1 - 0.22 10.4 6.0 0.35 9.8 4.2 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) Utp14 PF04615.8 CDI86290.1 - 0.23 9.5 39.5 0.27 9.3 27.4 1.0 1 0 0 1 1 1 0 Utp14 protein DUF1510 PF07423.6 CDI86290.1 - 1.3 8.3 37.8 1.7 7.9 26.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DUF4045 PF13254.1 CDI86290.1 - 2.5 7.2 35.9 2.6 7.2 24.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Hid1 PF12722.2 CDI86290.1 - 3.2 5.3 40.6 3.7 5.1 28.2 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein CENP-T PF15511.1 CDI86290.1 - 3.9 6.6 33.6 4.7 6.3 23.3 1.0 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T FAM60A PF15396.1 CDI86290.1 - 8.8 6.0 35.0 12 5.5 24.3 1.2 1 0 0 1 1 1 0 Protein Family FAM60A K_channel_TID PF07941.6 CDI86291.1 - 0.039 14.1 1.5 0.039 14.1 1.0 6.5 5 2 2 7 7 7 0 Potassium channel Kv1.4 tandem inactivation domain Ribosomal_60s PF00428.14 CDI86292.1 - 0.0002 21.6 12.1 0.0002 21.6 8.4 16.4 8 4 3 11 11 11 3 60s Acidic ribosomal protein Herpes_LMP1 PF05297.6 CDI86292.1 - 5 5.9 7.6 14 4.4 5.3 1.7 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) SR-25 PF10500.4 CDI86293.1 - 7.1e-05 22.3 30.4 8.8e-05 22.0 21.0 1.0 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein CAF-1_p150 PF11600.3 CDI86293.1 - 1.8 7.8 32.5 2.5 7.4 22.5 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal PAT1 PF09770.4 CDI86293.1 - 3.1 5.9 53.0 3.1 5.9 36.7 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF4175 PF13779.1 CDI86293.1 - 3.6 5.1 55.1 3.7 5.1 38.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) RR_TM4-6 PF06459.7 CDI86293.1 - 8.4 6.2 25.8 9.5 6.0 17.9 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CR6_interact PF10147.4 CDI86294.1 - 0.0034 16.7 0.5 0.0059 15.9 0.3 1.3 1 0 0 1 1 1 1 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 PSI PF01437.20 CDI86294.1 - 0.094 12.8 1.6 11 6.2 0.1 2.3 2 0 0 2 2 2 0 Plexin repeat Ank_2 PF12796.2 CDI86295.1 - 4.9e-22 78.0 2.0 6.3e-19 68.1 0.1 3.5 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 CDI86295.1 - 8.2e-21 72.7 1.6 1.3e-09 37.3 0.0 5.5 5 1 0 5 5 5 3 Ankyrin repeat Ank_4 PF13637.1 CDI86295.1 - 2.6e-16 59.6 3.6 6.2e-09 36.1 0.1 4.9 3 1 2 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 CDI86295.1 - 9.3e-15 53.2 6.0 1.3e-06 28.0 0.0 6.8 7 0 0 7 7 7 3 Ankyrin repeat Ank_5 PF13857.1 CDI86295.1 - 2.8e-11 43.2 9.7 2.9e-08 33.6 0.2 5.3 4 1 1 5 5 5 2 Ankyrin repeats (many copies) SET PF00856.23 CDI86295.1 - 0.0041 17.4 0.0 0.013 15.7 0.0 1.9 2 0 0 2 2 2 1 SET domain Neur_chan_memb PF02932.11 CDI86297.1 - 2 8.2 41.9 2.9 7.7 29.1 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Nucleoplasmin PF03066.10 CDI86298.1 - 0.011 15.2 2.0 0.014 14.8 1.4 1.1 1 0 0 1 1 1 0 Nucleoplasmin PBP1_TM PF14812.1 CDI86298.1 - 2.1 8.7 8.5 3.2 8.1 5.9 1.2 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Sigma70_ner PF04546.8 CDI86298.1 - 3.8 7.0 6.8 4.7 6.7 4.7 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region FLO_LFY PF01698.11 CDI86300.1 - 0.44 9.3 20.4 0.46 9.2 14.1 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein SprA-related PF12118.3 CDI86300.1 - 0.48 9.7 49.8 0.56 9.4 34.5 1.0 1 0 0 1 1 1 0 SprA-related family PAT1 PF09770.4 CDI86300.1 - 0.66 8.1 55.1 0.71 8.0 38.2 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF2072 PF09845.4 CDI86300.1 - 0.8 9.6 10.0 0.98 9.3 6.9 1.2 1 0 0 1 1 1 0 Zn-ribbon containing protein (DUF2072) Tim54 PF11711.3 CDI86300.1 - 0.82 8.1 16.0 0.93 8.0 11.1 1.0 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 FYDLN_acid PF09538.5 CDI86300.1 - 0.87 10.1 10.4 1.1 9.8 7.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) RR_TM4-6 PF06459.7 CDI86300.1 - 0.94 9.3 22.3 1.1 9.1 15.4 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 FAM60A PF15396.1 CDI86300.1 - 1.3 8.6 18.6 1.5 8.4 12.9 1.1 1 0 0 1 1 1 0 Protein Family FAM60A DUF4045 PF13254.1 CDI86300.1 - 1.4 8.1 20.1 1.5 8.0 14.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Pox_Ag35 PF03286.9 CDI86300.1 - 1.7 8.1 15.2 1.8 8.0 10.5 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein BORG_CEP PF14957.1 CDI86300.1 - 1.7 9.5 15.2 2.5 9.0 10.6 1.3 1 0 0 1 1 1 0 Cdc42 effector FAM176 PF14851.1 CDI86300.1 - 1.8 8.2 14.5 2.5 7.7 10.1 1.2 1 0 0 1 1 1 0 FAM176 family TFIIA PF03153.8 CDI86300.1 - 1.8 8.4 40.8 1.8 8.3 28.3 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF1510 PF07423.6 CDI86300.1 - 1.8 7.8 25.3 2.1 7.6 17.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Baculo_PP31 PF05311.6 CDI86300.1 - 2.2 7.4 23.5 2.5 7.2 16.3 1.1 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) Cellulose_synt PF03552.9 CDI86300.1 - 2.3 6.3 9.5 2.4 6.3 6.6 1.0 1 0 0 1 1 1 0 Cellulose synthase NARP1 PF12569.3 CDI86300.1 - 2.4 6.8 23.6 2.6 6.6 16.4 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Peptidase_U57 PF05582.7 CDI86300.1 - 2.5 7.0 18.2 3 6.7 12.6 1.1 1 0 0 1 1 1 0 YabG peptidase U57 Raftlin PF15250.1 CDI86300.1 - 2.7 6.3 21.6 3 6.2 15.0 1.0 1 0 0 1 1 1 0 Raftlin Peptidase_S15 PF02129.13 CDI86300.1 - 2.8 7.3 18.7 3.2 7.0 13.0 1.0 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) BTV_NS2 PF04514.7 CDI86300.1 - 3.1 6.5 17.8 3.3 6.5 12.4 1.0 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Ycf1 PF05758.7 CDI86300.1 - 3.3 5.3 22.8 3.4 5.2 15.8 1.0 1 0 0 1 1 1 0 Ycf1 GAGA_bind PF06217.7 CDI86300.1 - 3.6 7.4 22.7 4.5 7.1 15.7 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family Rtf2 PF04641.7 CDI86300.1 - 3.6 6.7 24.5 4.3 6.4 17.0 1.0 1 0 0 1 1 1 0 Rtf2 RING-finger PPP4R2 PF09184.6 CDI86300.1 - 3.8 6.9 18.6 4.4 6.7 12.9 1.1 1 0 0 1 1 1 0 PPP4R2 Pal1 PF08316.6 CDI86300.1 - 4.8 7.6 12.5 6.4 7.2 8.7 1.2 1 0 0 1 1 1 0 Pal1 cell morphology protein AIF_C PF14721.1 CDI86300.1 - 4.9 7.4 19.8 7.1 6.8 13.7 1.3 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term SAGA-Tad1 PF12767.2 CDI86300.1 - 5.4 6.6 27.6 6.6 6.3 19.2 1.1 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit CDC45 PF02724.9 CDI86300.1 - 5.7 4.8 23.0 6 4.7 15.9 1.0 1 0 0 1 1 1 0 CDC45-like protein Asp-B-Hydro_N PF05279.6 CDI86300.1 - 5.8 6.6 17.2 6.3 6.5 11.9 1.0 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region AUX_IAA PF02309.11 CDI86300.1 - 5.9 6.5 22.1 6.9 6.3 15.3 1.1 1 0 0 1 1 1 0 AUX/IAA family Cyto_heme_lyase PF01265.12 CDI86300.1 - 6 6.3 23.7 6.7 6.2 16.5 1.0 1 0 0 1 1 1 0 Cytochrome c/c1 heme lyase Bud13 PF09736.4 CDI86300.1 - 6.9 6.9 31.0 9.3 6.4 21.5 1.1 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex DUF913 PF06025.7 CDI86300.1 - 8.4 5.0 14.7 9.5 4.8 10.2 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Spore_coat_CotO PF14153.1 CDI86300.1 - 8.5 5.7 34.2 10 5.5 23.7 1.0 1 0 0 1 1 1 0 Spore coat protein CotO Paf1 PF03985.8 CDI86300.1 - 9.6 4.8 29.7 12 4.5 20.6 1.0 1 0 0 1 1 1 0 Paf1 Hid1 PF12722.2 CDI86300.1 - 9.9 3.6 25.3 11 3.5 17.5 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Corona_nucleoca PF00937.13 CDI86302.1 - 0.0097 14.8 11.4 0.015 14.2 7.9 1.3 1 0 0 1 1 1 1 Coronavirus nucleocapsid protein DUF4614 PF15391.1 CDI86302.1 - 0.63 9.7 18.1 1.4 8.6 12.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) Apt1 PF10351.4 CDI86302.1 - 3.9 6.2 6.9 5.1 5.8 4.8 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain eIF-4B PF06273.6 CDI86303.1 - 0.23 10.1 2.1 0.27 9.9 1.4 1.0 1 0 0 1 1 1 0 Plant specific eukaryotic initiation factor 4B SR-25 PF10500.4 CDI86304.1 - 0.0012 18.3 14.6 0.0012 18.3 10.1 26.1 17 6 6 25 25 25 7 Nuclear RNA-splicing-associated protein Kinase-like PF14531.1 CDI86306.1 - 1.7e-06 27.2 0.0 2.9e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Pkinase PF00069.20 CDI86306.1 - 0.0048 16.0 0.0 0.0074 15.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Mpp10 PF04006.7 CDI86307.1 - 1.9e-08 33.1 160.2 7.8e-06 24.5 0.0 5.1 2 1 1 4 4 4 3 Mpp10 protein PAT1 PF09770.4 CDI86308.1 - 0.00095 17.5 62.8 0.0011 17.3 43.5 1.0 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 SR-25 PF10500.4 CDI86308.1 - 0.039 13.4 24.5 0.06 12.8 17.0 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein PLRV_ORF5 PF01690.12 CDI86308.1 - 0.099 11.7 22.5 0.11 11.5 15.6 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Dapper PF15268.1 CDI86308.1 - 0.37 9.5 35.9 0.47 9.1 24.9 1.0 1 0 0 1 1 1 0 Dapper CDC45 PF02724.9 CDI86308.1 - 2.1 6.2 26.2 3 5.7 18.2 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF2146 PF10220.4 CDI86308.1 - 2.1 6.2 23.6 2.7 5.8 16.4 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2146) Ribosomal_60s PF00428.14 CDI86308.1 - 2.3 8.6 12.6 0.52 10.7 6.0 1.9 2 0 0 2 2 2 0 60s Acidic ribosomal protein Nha1_C PF08619.5 CDI86308.1 - 3.1 6.9 30.6 4.5 6.4 21.2 1.2 1 0 0 1 1 1 0 Alkali metal cation/H+ antiporter Nha1 C terminus DNA_pol_viral_N PF00242.12 CDI86308.1 - 5.4 5.9 27.7 6.3 5.7 19.2 1.1 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain Herpes_UL87 PF03043.9 CDI86308.1 - 6.5 5.0 17.4 8.2 4.6 12.0 1.2 1 0 0 1 1 1 0 Herpesvirus UL87 family Parvo_coat PF00740.13 CDI86308.1 - 9.5 5.0 32.1 12 4.6 22.2 1.1 1 0 0 1 1 1 0 Parvovirus coat protein VP2 Claudin_2 PF13903.1 CDI86309.1 - 9.2 5.9 15.1 65 3.1 10.5 2.1 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction AAA_28 PF13521.1 CDI86311.1 - 0.0035 17.3 2.4 0.0078 16.1 1.6 1.6 1 1 0 1 1 1 1 AAA domain MAS20 PF02064.10 CDI86311.1 - 0.004 17.0 6.4 0.18 11.7 0.2 2.3 2 0 0 2 2 2 2 MAS20 protein import receptor DUF3464 PF11947.3 CDI86311.1 - 0.0055 16.1 2.1 0.17 11.3 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3464) UPF0093 PF03653.8 CDI86311.1 - 0.0059 16.5 0.8 0.09 12.7 0.1 2.2 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0093) U1snRNP70_N PF12220.3 CDI86311.1 - 0.016 15.4 10.0 0.055 13.7 0.8 2.6 3 0 0 3 3 3 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal CD20 PF04103.10 CDI86311.1 - 0.022 14.6 0.4 6.8 6.5 0.0 2.1 2 0 0 2 2 2 0 CD20-like family Ndc1_Nup PF09531.5 CDI86311.1 - 0.058 11.8 5.7 0.068 11.5 4.0 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF1840 PF08895.6 CDI86311.1 - 0.064 13.2 17.9 0.087 12.8 4.8 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF1840) FimP PF09766.4 CDI86311.1 - 0.075 12.0 15.6 0.65 9.0 2.1 2.2 2 0 0 2 2 2 0 Fms-interacting protein PLRV_ORF5 PF01690.12 CDI86311.1 - 0.11 11.6 6.7 0.13 11.3 4.6 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein LIM_bind PF01803.11 CDI86311.1 - 0.21 10.6 13.4 0.056 12.5 1.2 2.1 2 0 0 2 2 2 0 LIM-domain binding protein Pex16 PF08610.5 CDI86311.1 - 0.22 10.5 7.0 0.55 9.1 0.1 2.1 2 0 0 2 2 2 0 Peroxisomal membrane protein (Pex16) IncA PF04156.9 CDI86311.1 - 0.42 10.1 19.4 1.3 8.5 3.9 2.2 2 0 0 2 2 2 0 IncA protein DUF912 PF06024.7 CDI86311.1 - 0.43 10.6 3.7 2 8.4 0.1 2.4 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) EphA2_TM PF14575.1 CDI86311.1 - 0.52 10.7 2.7 17 5.9 0.0 2.6 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain DUF3729 PF12526.3 CDI86311.1 - 0.7 11.2 4.7 0.96 10.8 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3729) G0-G1_switch_2 PF15103.1 CDI86311.1 - 0.83 9.9 10.8 0.48 10.6 0.8 2.6 3 0 0 3 3 2 0 G0/G1 switch protein 2 DUF4414 PF14377.1 CDI86311.1 - 1 9.2 15.9 3.4 7.6 2.8 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4414) Baculo_PP31 PF05311.6 CDI86311.1 - 1.1 8.4 9.3 0.62 9.2 1.5 2.1 2 0 0 2 2 2 0 Baculovirus 33KDa late protein (PP31) Shisa PF13908.1 CDI86311.1 - 1.7 8.8 11.8 2.5 8.2 2.3 2.2 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator OATP PF03137.15 CDI86311.1 - 2.5 6.0 4.8 8.1 4.3 0.4 2.0 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Serinc PF03348.10 CDI86311.1 - 2.5 6.6 7.2 2.3 6.8 0.5 2.1 2 0 0 2 2 2 0 Serine incorporator (Serinc) UPF0233 PF06781.7 CDI86311.1 - 4.2 7.0 4.7 6.1 6.5 0.1 2.5 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0233) ATAD4 PF15321.1 CDI86311.1 - 5.5 8.0 10.6 11 7.0 0.8 2.4 2 0 0 2 2 2 0 ATPase family AAA domain containing 4 Ctr PF04145.10 CDI86311.1 - 5.6 7.0 13.5 5 7.1 2.6 2.3 1 1 1 2 2 2 0 Ctr copper transporter family AIF_C PF14721.1 CDI86311.1 - 7 6.9 9.3 12 6.1 1.4 2.4 3 0 0 3 3 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Dehydrin PF00257.14 CDI86311.1 - 8.9 6.6 10.4 12 6.2 0.6 2.2 2 0 0 2 2 2 0 Dehydrin BUD22 PF09073.5 CDI86312.1 - 0.0004 19.5 27.4 0.0004 19.5 19.0 3.2 2 1 1 3 3 3 1 BUD22 DUF1510 PF07423.6 CDI86312.1 - 0.0048 16.2 19.3 0.0048 16.2 13.4 3.5 3 1 0 4 4 4 1 Protein of unknown function (DUF1510) Trypan_PARP PF05887.6 CDI86312.1 - 0.005 16.6 15.3 0.005 16.6 10.6 3.7 3 1 1 4 4 4 1 Procyclic acidic repetitive protein (PARP) FAM176 PF14851.1 CDI86312.1 - 0.016 14.8 8.0 0.016 14.8 5.5 4.9 3 1 2 5 5 5 0 FAM176 family Sigma70_ner PF04546.8 CDI86312.1 - 0.47 10.0 50.6 0.073 12.6 7.6 3.3 3 0 0 3 3 3 0 Sigma-70, non-essential region TFIIA PF03153.8 CDI86312.1 - 1.7 8.4 53.0 2.6 7.8 36.7 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SDA1 PF05285.7 CDI86312.1 - 4.1 6.6 62.3 0.31 10.2 5.1 3.2 3 0 0 3 3 3 0 SDA1 BAF1_ABF1 PF04684.8 CDI86312.1 - 5.8 5.6 27.3 0.15 10.8 12.6 2.1 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor SR-25 PF10500.4 CDI86313.1 - 4.3 6.7 15.0 4.4 6.7 10.4 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Mucin PF01456.12 CDI86313.1 - 4.6 7.0 27.2 6.4 6.5 18.8 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein Ribosomal_60s PF00428.14 CDI86313.1 - 6.8 7.1 42.3 9.6 6.6 13.2 2.3 2 0 0 2 2 2 0 60s Acidic ribosomal protein DUF1183 PF06682.7 CDI86314.1 - 0.69 9.4 27.9 0.93 9.0 19.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) Herpes_DNAp_acc PF04929.7 CDI86314.1 - 1.2 8.0 24.5 1.5 7.6 17.0 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Kinesin PF00225.18 CDI86315.1 - 7.4e-40 136.6 0.2 7.4e-40 136.6 0.1 1.3 2 0 0 2 2 2 1 Kinesin motor domain FliD_N PF02465.13 CDI86315.1 - 1.4 9.3 9.1 12 6.3 0.0 2.2 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus DUF588 PF04535.7 CDI86317.1 - 0.034 13.7 0.1 0.047 13.2 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF588) Hid1 PF12722.2 CDI86317.1 - 3.1 5.3 42.1 3.7 5.1 29.2 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Pkinase PF00069.20 CDI86319.1 - 2.6e-48 164.4 5.4 9.2e-32 110.1 0.0 3.2 2 1 1 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.12 CDI86319.1 - 2.4e-23 82.5 7.4 1.3e-13 50.6 0.0 3.2 2 1 1 3 3 3 2 Protein tyrosine kinase Corona_nucleoca PF00937.13 CDI86319.1 - 0.55 9.1 49.8 0.0095 14.9 12.6 2.2 2 0 0 2 2 2 0 Coronavirus nucleocapsid protein V_ATPase_I PF01496.14 CDI86319.1 - 3.8 5.2 10.9 5.7 4.6 7.5 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Hex_IIIa PF02455.11 CDI86319.1 - 5.6 5.5 28.7 1.1 7.8 7.8 2.1 2 0 0 2 2 2 0 Hexon-associated protein (IIIa) SAGA-Tad1 PF12767.2 CDI86319.1 - 7.3 6.1 41.8 0.19 11.4 13.1 2.2 2 0 0 2 2 2 0 Transcriptional regulator of RNA polII, SAGA, subunit DAGAT PF03982.8 CDI86320.1 - 1.2e-24 86.5 0.1 1e-23 83.4 0.0 2.0 2 0 0 2 2 2 1 Diacylglycerol acyltransferase Acyltransferase PF01553.16 CDI86320.1 - 0.019 14.3 0.0 0.038 13.4 0.0 1.5 1 0 0 1 1 1 0 Acyltransferase L51_S25_CI-B8 PF05047.11 CDI86321.1 - 5.1e-06 26.1 0.0 9.7e-06 25.2 0.0 1.5 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain ABC_tran PF00005.22 CDI86322.1 - 3.1e-33 114.9 0.0 6.6e-33 113.9 0.0 1.6 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.18 CDI86322.1 - 1e-17 64.4 5.2 1.5e-17 63.9 3.6 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region AAA_21 PF13304.1 CDI86322.1 - 1e-06 28.9 0.0 0.00018 21.6 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 CDI86322.1 - 0.00023 21.1 3.9 0.00029 20.8 0.1 2.7 2 1 0 2 2 2 1 AAA ATPase domain SMC_N PF02463.14 CDI86322.1 - 0.00059 19.1 0.0 0.031 13.4 0.0 2.1 1 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.1 CDI86322.1 - 0.004 17.3 0.1 0.062 13.4 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 CDI86322.1 - 0.0044 16.5 0.0 0.012 15.1 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain Zeta_toxin PF06414.7 CDI86322.1 - 0.0053 15.8 0.0 0.011 14.8 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin MobB PF03205.9 CDI86322.1 - 0.0058 16.3 0.0 0.016 14.9 0.0 1.7 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_25 PF13481.1 CDI86322.1 - 0.018 14.4 0.6 0.066 12.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.8 CDI86322.1 - 0.022 13.7 0.0 0.039 12.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_18 PF13238.1 CDI86322.1 - 0.031 14.5 0.0 0.064 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 CDI86322.1 - 0.04 13.5 0.0 0.12 12.0 0.0 1.8 1 0 0 1 1 1 0 NACHT domain AAA_17 PF13207.1 CDI86322.1 - 0.042 14.6 0.0 0.093 13.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 CDI86322.1 - 0.055 13.3 0.1 0.21 11.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain DUF258 PF03193.11 CDI86322.1 - 0.067 12.3 0.1 0.15 11.2 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Miro PF08477.8 CDI86322.1 - 0.078 13.4 0.0 0.17 12.3 0.0 1.6 1 0 0 1 1 1 0 Miro-like protein AAA PF00004.24 CDI86322.1 - 0.1 12.8 0.0 0.8 9.9 0.0 2.4 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.18 CDI86322.1 - 0.16 11.9 0.0 0.47 10.4 0.0 1.8 2 0 0 2 2 1 0 50S ribosome-binding GTPase Pox_A32 PF04665.7 CDI86322.1 - 0.21 10.8 0.0 0.36 10.1 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein Ribosomal_60s PF00428.14 CDI86322.1 - 2 8.8 11.9 6.5 7.2 8.2 1.9 1 0 0 1 1 1 0 60s Acidic ribosomal protein DUF3792 PF12670.2 CDI86322.1 - 8 6.3 9.3 3.9 7.3 2.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3792) Surface_antigen PF11054.3 CDI86323.1 - 3e-54 184.0 3.8 1.1e-39 136.3 1.7 2.0 1 1 1 2 2 2 2 Sporozoite TA4 surface antigen GCD14 PF08704.5 CDI86324.1 - 5.7e-64 215.9 0.0 3.7e-40 137.9 0.0 2.2 2 0 0 2 2 2 2 tRNA methyltransferase complex GCD14 subunit Methyltransf_31 PF13847.1 CDI86324.1 - 1.4e-05 24.7 0.0 0.014 15.0 0.0 2.7 3 0 0 3 3 3 2 Methyltransferase domain Methyltransf_18 PF12847.2 CDI86324.1 - 0.00015 22.3 0.0 0.00031 21.2 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 CDI86324.1 - 0.0029 17.6 0.0 0.0067 16.4 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 CDI86324.1 - 0.014 14.9 0.0 0.029 13.9 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) RrnaAD PF00398.15 CDI86324.1 - 0.041 12.9 0.0 0.065 12.2 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_23 PF13489.1 CDI86324.1 - 0.068 12.8 0.0 0.26 11.0 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 CDI86324.1 - 0.095 12.0 0.0 0.76 9.1 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase small domain Surface_antigen PF11054.3 CDI86325.1 - 9.7e-65 218.4 3.0 1.1e-64 218.2 2.1 1.0 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen Surface_antigen PF11054.3 CDI86326.1 - 8.1e-135 448.0 16.5 1.2e-66 224.7 2.0 3.0 2 1 1 3 3 3 3 Sporozoite TA4 surface antigen OmdA PF13376.1 CDI86326.1 - 0.0076 15.8 0.0 0.65 9.7 0.0 2.5 2 0 0 2 2 2 2 Bacteriocin-protection, YdeI or OmpD-Associated Surface_antigen PF11054.3 CDI86327.1 - 5e-73 245.6 7.0 6.1e-73 245.3 4.9 1.0 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen Surface_antigen PF11054.3 CDI86328.1 - 1e-29 103.6 2.8 1.2e-29 103.4 1.9 1.0 1 0 0 1 1 1 1 Sporozoite TA4 surface antigen Scs3p PF10261.4 CDI86330.1 - 0.16 10.9 0.0 0.16 10.9 0.0 5.2 5 1 1 6 6 6 0 Inositol phospholipid synthesis and fat-storage-inducing TM DUF1510 PF07423.6 CDI86331.1 - 1.6e-05 24.3 9.8 1.9e-05 24.1 6.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) SpoIIIAH PF12685.2 CDI86331.1 - 7.1e-05 22.3 6.6 9.1e-05 22.0 4.6 1.1 1 0 0 1 1 1 1 SpoIIIAH-like protein FAM176 PF14851.1 CDI86331.1 - 0.00032 20.4 3.2 0.0004 20.1 2.2 1.2 1 0 0 1 1 1 1 FAM176 family TRAP_alpha PF03896.11 CDI86331.1 - 0.00034 19.6 1.6 0.0004 19.4 1.1 1.0 1 0 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit Kei1 PF08552.6 CDI86331.1 - 0.00039 20.1 2.9 0.00047 19.8 2.0 1.2 1 0 0 1 1 1 1 Inositolphosphorylceramide synthase subunit Kei1 RIC3 PF15361.1 CDI86331.1 - 0.00073 19.7 9.5 0.00088 19.5 6.6 1.1 1 0 0 1 1 1 1 Resistance to inhibitors of cholinesterase homologue 3 Ycf1 PF05758.7 CDI86331.1 - 0.00089 17.1 13.1 0.00098 16.9 9.1 1.0 1 0 0 1 1 1 1 Ycf1 Ctr PF04145.10 CDI86331.1 - 0.0016 18.4 3.7 0.0021 18.1 2.6 1.1 1 0 0 1 1 1 1 Ctr copper transporter family DUF4446 PF14584.1 CDI86331.1 - 0.0038 17.0 5.5 0.004 17.0 3.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4446) Serinc PF03348.10 CDI86331.1 - 0.0059 15.3 8.7 0.0071 15.0 6.0 1.1 1 0 0 1 1 1 1 Serine incorporator (Serinc) Gastrin PF00918.12 CDI86331.1 - 0.0074 17.0 14.8 0.0089 16.8 10.3 1.2 1 0 0 1 1 1 1 Gastrin/cholecystokinin family DUF4512 PF14975.1 CDI86331.1 - 0.013 16.2 8.1 0.016 15.9 5.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4512) Folate_carrier PF01770.13 CDI86331.1 - 0.014 13.9 7.4 0.014 13.8 5.1 1.0 1 0 0 1 1 1 0 Reduced folate carrier OATP PF03137.15 CDI86331.1 - 0.014 13.5 8.7 0.015 13.3 6.0 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Peptidase_M56 PF05569.6 CDI86331.1 - 0.014 14.4 1.9 0.017 14.1 1.3 1.0 1 0 0 1 1 1 0 BlaR1 peptidase M56 Nucleoside_tran PF01733.13 CDI86331.1 - 0.016 14.3 4.7 0.018 14.2 3.2 1.0 1 0 0 1 1 1 0 Nucleoside transporter SID-1_RNA_chan PF13965.1 CDI86331.1 - 0.016 13.3 6.9 0.018 13.1 4.8 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DUF2946 PF11162.3 CDI86331.1 - 0.017 15.3 2.9 0.021 15.0 2.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2946) RNA_pol_Rpc4 PF05132.9 CDI86331.1 - 0.023 14.6 12.4 0.028 14.4 8.6 1.1 1 0 0 1 1 1 0 RNA polymerase III RPC4 Pap_E4 PF02711.9 CDI86331.1 - 0.023 15.4 12.9 0.026 15.3 8.9 1.1 1 0 0 1 1 1 0 E4 protein Baculo_PP31 PF05311.6 CDI86331.1 - 0.033 13.4 11.5 0.034 13.4 8.0 1.0 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) Stig1 PF04885.8 CDI86331.1 - 0.033 14.4 3.2 0.039 14.1 2.2 1.2 1 0 0 1 1 1 0 Stigma-specific protein, Stig1 DUF2370 PF10176.4 CDI86331.1 - 0.046 13.0 5.1 0.047 13.0 3.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) DUF3530 PF12048.3 CDI86331.1 - 0.05 12.5 21.2 0.066 12.1 14.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) DUF3450 PF11932.3 CDI86331.1 - 0.051 12.8 24.6 0.059 12.6 17.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF4094 PF13334.1 CDI86331.1 - 0.065 13.6 14.0 0.12 12.7 9.7 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4094) Tmemb_9 PF05434.6 CDI86331.1 - 0.069 12.8 16.2 0.078 12.7 11.2 1.0 1 0 0 1 1 1 0 TMEM9 PIG-P PF08510.7 CDI86331.1 - 0.073 12.7 4.4 0.22 11.1 3.0 1.7 1 1 0 1 1 1 0 PIG-P YfhO PF09586.5 CDI86331.1 - 0.11 10.5 7.9 0.12 10.3 5.5 1.1 1 0 0 1 1 1 0 Bacterial membrane protein YfhO DUF3260 PF11658.3 CDI86331.1 - 0.11 10.6 11.7 0.11 10.6 8.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3260) DUF3394 PF11874.3 CDI86331.1 - 0.11 12.0 3.9 0.14 11.6 2.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3394) ATG22 PF11700.3 CDI86331.1 - 0.11 10.9 4.5 0.15 10.4 3.1 1.4 1 1 0 1 1 1 0 Vacuole effluxer Atg22 like ETRAMP PF09716.5 CDI86331.1 - 0.12 12.3 5.0 0.48 10.4 3.5 1.8 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) Endonuc_Holl PF10107.4 CDI86331.1 - 0.15 11.7 12.9 0.16 11.6 9.0 1.1 1 0 0 1 1 1 0 Endonuclease related to archaeal Holliday junction resolvase Neur_chan_memb PF02932.11 CDI86331.1 - 0.16 11.8 7.4 0.18 11.6 5.1 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region UPF0565 PF10561.4 CDI86331.1 - 0.19 10.5 9.1 0.21 10.4 6.3 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0565 IncA PF04156.9 CDI86331.1 - 0.21 11.1 30.4 0.26 10.8 21.1 1.0 1 0 0 1 1 1 0 IncA protein Pex24p PF06398.6 CDI86331.1 - 0.22 10.2 3.1 0.39 9.4 2.1 1.5 1 1 0 1 1 1 0 Integral peroxisomal membrane peroxin Mem_trans PF03547.13 CDI86331.1 - 0.23 9.7 7.0 0.25 9.5 4.8 1.1 1 0 0 1 1 1 0 Membrane transport protein Pescadillo_N PF06732.6 CDI86331.1 - 0.24 10.6 7.4 0.3 10.2 5.2 1.3 1 0 0 1 1 1 0 Pescadillo N-terminus DUF3292 PF11696.3 CDI86331.1 - 0.24 9.2 4.3 0.24 9.2 3.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) Tim54 PF11711.3 CDI86331.1 - 0.24 9.9 14.6 0.29 9.7 10.1 1.0 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Dynamin_N PF00350.18 CDI86331.1 - 0.28 10.9 7.3 0.28 10.9 5.0 1.1 1 0 0 1 1 1 0 Dynamin family PBP1_TM PF14812.1 CDI86331.1 - 0.29 11.4 10.9 0.52 10.6 7.6 1.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Conotoxin PF02950.12 CDI86331.1 - 0.29 11.9 16.8 19 6.1 11.6 2.1 1 1 0 1 1 1 0 Conotoxin DUF1980 PF09323.5 CDI86331.1 - 0.29 10.8 10.5 0.35 10.6 7.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) NPR3 PF03666.8 CDI86331.1 - 0.32 9.5 15.2 0.36 9.3 10.6 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 BORG_CEP PF14957.1 CDI86331.1 - 0.34 11.8 11.2 0.41 11.5 7.8 1.1 1 0 0 1 1 1 0 Cdc42 effector SR-25 PF10500.4 CDI86331.1 - 0.34 10.3 16.0 0.37 10.2 11.1 1.0 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF2828 PF11443.3 CDI86331.1 - 0.35 9.0 10.2 0.34 9.0 7.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) RICTOR_N PF14664.1 CDI86331.1 - 0.41 9.1 3.2 0.4 9.2 2.2 1.1 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR, N-term Sex_peptide PF08138.6 CDI86331.1 - 0.41 10.5 7.7 12 5.7 5.4 2.4 1 1 0 1 1 1 0 Sex peptide (SP) family DDHD PF02862.12 CDI86331.1 - 0.41 10.4 17.1 0.47 10.2 11.8 1.0 1 0 0 1 1 1 0 DDHD domain HCO3_cotransp PF00955.16 CDI86331.1 - 0.46 9.0 3.4 0.45 9.1 2.4 1.0 1 0 0 1 1 1 0 HCO3- transporter family YABBY PF04690.8 CDI86331.1 - 0.48 10.6 9.0 0.53 10.5 6.3 1.1 1 0 0 1 1 1 0 YABBY protein Neur PF00064.13 CDI86331.1 - 0.49 8.4 3.6 0.51 8.3 2.5 1.0 1 0 0 1 1 1 0 Neuraminidase Tmem26 PF09772.4 CDI86331.1 - 0.53 9.4 4.0 0.58 9.3 2.8 1.2 1 0 0 1 1 1 0 Transmembrane protein 26 FAM91_C PF14648.1 CDI86331.1 - 0.54 9.0 5.6 0.55 8.9 3.9 1.0 1 0 0 1 1 1 0 FAM91 C-terminus Band_3_cyto PF07565.8 CDI86331.1 - 0.71 9.3 15.7 0.76 9.2 10.9 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain RP-C_C PF11800.3 CDI86331.1 - 0.79 9.3 15.4 0.88 9.2 10.7 1.0 1 0 0 1 1 1 0 Replication protein C C-terminal region HGTP_anticodon2 PF12745.2 CDI86331.1 - 0.86 8.6 15.7 0.94 8.5 10.8 1.0 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs Raftlin PF15250.1 CDI86331.1 - 0.87 8.0 15.4 0.92 7.9 10.6 1.0 1 0 0 1 1 1 0 Raftlin SpoIIP PF07454.6 CDI86331.1 - 0.96 8.5 15.4 1.1 8.3 10.7 1.0 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) ALG3 PF05208.8 CDI86331.1 - 1 8.5 4.3 1.2 8.3 3.0 1.2 1 0 0 1 1 1 0 ALG3 protein SARG PF15385.1 CDI86331.1 - 1.1 8.5 23.3 1.2 8.3 16.2 1.0 1 0 0 1 1 1 0 Specifically androgen-regulated gene protein Presenilin PF01080.12 CDI86331.1 - 1.1 8.0 9.1 1.2 7.8 6.3 1.1 1 0 0 1 1 1 0 Presenilin GOLD_2 PF13897.1 CDI86331.1 - 1.1 9.4 7.0 1.4 9.1 4.9 1.3 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking Di19_C PF14571.1 CDI86331.1 - 1.1 9.5 15.4 1.4 9.2 10.7 1.1 1 0 0 1 1 1 0 Stress-induced protein Di19, C-terminal DUF3357 PF11837.3 CDI86331.1 - 1.1 9.0 8.4 36 4.2 5.8 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF3357) G-alpha PF00503.15 CDI86331.1 - 1.2 7.7 19.1 1.4 7.5 13.3 1.0 1 0 0 1 1 1 0 G-protein alpha subunit DUF4220 PF13968.1 CDI86331.1 - 1.4 7.9 7.5 1.5 7.8 5.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4220) YqfQ PF14181.1 CDI86331.1 - 1.5 8.8 22.6 1.8 8.5 15.7 1.1 1 0 0 1 1 1 0 YqfQ-like protein RBP_receptor PF14752.1 CDI86331.1 - 2 6.6 5.9 2.4 6.4 4.1 1.1 1 0 0 1 1 1 0 Retinol binding protein receptor SAPS PF04499.10 CDI86331.1 - 2 6.9 14.5 2.3 6.7 10.1 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Glyco_transf_15 PF01793.11 CDI86331.1 - 2.1 7.2 18.4 2.5 6.9 12.8 1.0 1 0 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase SeqA PF03925.8 CDI86331.1 - 2.5 7.7 15.1 2.8 7.5 10.5 1.1 1 0 0 1 1 1 0 SeqA protein Shisa PF13908.1 CDI86331.1 - 2.6 8.1 14.3 3.2 7.8 9.9 1.2 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator RR_TM4-6 PF06459.7 CDI86331.1 - 2.7 7.8 21.6 3.2 7.5 14.9 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 GAGA_bind PF06217.7 CDI86331.1 - 2.7 7.8 18.1 3.1 7.6 12.5 1.0 1 0 0 1 1 1 0 GAGA binding protein-like family AIF_C PF14721.1 CDI86331.1 - 3.2 7.9 16.5 4 7.7 11.4 1.1 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term TT_ORF1 PF02956.9 CDI86331.1 - 3.3 6.0 14.1 3.6 5.9 9.8 1.0 1 0 0 1 1 1 0 TT viral orf 1 VID27 PF08553.5 CDI86331.1 - 3.4 5.7 13.0 3.6 5.6 9.0 1.0 1 0 0 1 1 1 0 VID27 cytoplasmic protein PSK PF06404.7 CDI86331.1 - 3.5 8.4 14.9 24 5.7 10.3 1.9 1 1 0 1 1 1 0 Phytosulfokine precursor protein (PSK) DUF2126 PF09899.4 CDI86331.1 - 3.5 5.5 15.2 3.9 5.3 10.6 1.0 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) DUF3449 PF11931.3 CDI86331.1 - 3.5 7.0 18.6 4.3 6.8 12.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3449) DUF2232 PF09991.4 CDI86331.1 - 3.5 6.5 9.4 4.9 6.0 6.5 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) Peptidase_S49_N PF08496.5 CDI86331.1 - 3.6 7.3 17.9 5.7 6.7 12.4 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Pox_Ag35 PF03286.9 CDI86331.1 - 3.6 7.0 16.5 4.4 6.7 11.4 1.0 1 0 0 1 1 1 0 Pox virus Ag35 surface protein OAD_gamma PF04277.8 CDI86331.1 - 3.7 8.0 7.6 31 5.0 5.2 2.0 1 1 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain DUF106 PF01956.11 CDI86331.1 - 3.9 6.9 14.0 4.5 6.7 9.7 1.2 1 0 0 1 1 1 0 Integral membrane protein DUF106 DUF3381 PF11861.3 CDI86331.1 - 4 6.9 22.7 4.8 6.6 15.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) Hid1 PF12722.2 CDI86331.1 - 4.3 4.8 20.0 4.9 4.7 13.9 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein CPSF100_C PF13299.1 CDI86331.1 - 5.1 7.2 17.3 5.6 7.1 12.0 1.0 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal NARP1 PF12569.3 CDI86331.1 - 5.2 5.6 21.6 6 5.4 15.0 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 FliP PF00813.15 CDI86331.1 - 5.5 6.6 8.5 7.2 6.2 5.9 1.2 1 0 0 1 1 1 0 FliP family HA2 PF04408.18 CDI86331.1 - 5.7 7.0 9.4 42 4.2 6.5 1.9 1 1 0 1 1 1 0 Helicase associated domain (HA2) LpxB PF02684.10 CDI86331.1 - 6.3 5.3 14.0 6.7 5.2 9.7 1.0 1 0 0 1 1 1 0 Lipid-A-disaccharide synthetase PCEMA1 PF07418.6 CDI86331.1 - 6.8 5.9 11.9 8.1 5.7 8.2 1.0 1 0 0 1 1 1 0 Acidic phosphoprotein precursor PCEMA1 Anoctamin PF04547.7 CDI86331.1 - 7.1 5.1 13.0 8.5 4.9 9.0 1.1 1 0 0 1 1 1 0 Calcium-activated chloride channel Dala_Dala_lig_N PF01820.16 CDI86331.1 - 7.2 6.9 10.8 11 6.3 7.5 1.4 1 0 0 1 1 1 0 D-ala D-ala ligase N-terminus Rer1 PF03248.8 CDI86331.1 - 7.4 6.1 10.0 27 4.2 6.9 1.8 1 1 0 1 1 1 0 Rer1 family DUF2215 PF10225.4 CDI86331.1 - 7.6 5.9 10.2 9.5 5.5 7.1 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) TraH_2 PF06871.6 CDI86331.1 - 7.9 5.8 9.6 9 5.6 6.6 1.2 1 0 0 1 1 1 0 TraH_2 GBP_C PF02841.9 CDI86331.1 - 8.3 5.4 30.6 9.2 5.3 21.2 1.0 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain RNA_pol_Rpb1_5 PF04998.12 CDI86331.1 - 9.2 5.4 11.7 10 5.2 8.1 1.0 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 OppC_N PF12911.2 CDI86331.1 - 9.5 5.6 6.4 26 4.2 4.4 1.9 1 1 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C FYDLN_acid PF09538.5 CDI86331.1 - 9.7 6.8 14.3 13 6.4 9.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) CAF-1_p150 PF11600.3 CDI86332.1 - 0.17 11.2 48.6 0.19 11.0 33.7 1.0 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal SprA-related PF12118.3 CDI86332.1 - 0.87 8.8 61.5 1.1 8.5 42.6 1.0 1 0 0 1 1 1 0 SprA-related family Corona_nucleoca PF00937.13 CDI86332.1 - 2.5 6.9 43.5 3.1 6.6 30.1 1.2 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein MIP-T3 PF10243.4 CDI86332.1 - 6.3 5.1 47.9 7.5 4.9 33.2 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Activator_LAG-3 PF11498.3 CDI86332.1 - 7.2 5.2 64.6 8.5 4.9 44.8 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 RNA_pol_Rpb1_5 PF04998.12 CDI86332.1 - 8 5.6 17.5 8.9 5.4 12.1 1.1 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 PAT1 PF09770.4 CDI86332.1 - 8.2 4.5 48.3 9.2 4.3 33.5 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Raftlin PF15250.1 CDI86332.1 - 8.6 4.7 29.6 11 4.4 20.5 1.2 1 0 0 1 1 1 0 Raftlin HemX PF04375.9 CDI86333.1 - 2.3e-05 23.1 24.7 2.3e-05 23.1 17.1 2.0 2 0 0 2 2 1 1 HemX AAA_23 PF13476.1 CDI86333.1 - 0.0051 17.1 2.6 0.0051 17.1 1.8 1.1 1 0 0 1 1 1 1 AAA domain zf-DHHC PF01529.15 CDI86333.1 - 0.032 13.6 1.1 0.032 13.6 0.8 1.2 1 0 0 1 1 1 0 DHHC palmitoyltransferase Hid1 PF12722.2 CDI86333.1 - 0.31 8.6 7.8 0.32 8.6 5.4 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF3439 PF11921.3 CDI86333.1 - 0.4 10.4 6.8 0.79 9.4 4.7 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Ycf1 PF05758.7 CDI86333.1 - 0.56 7.8 7.7 0.54 7.9 5.3 1.1 1 0 0 1 1 1 0 Ycf1 IATP PF04568.7 CDI86333.1 - 0.86 9.6 16.4 0.069 13.1 7.5 1.9 2 0 0 2 2 2 0 Mitochondrial ATPase inhibitor, IATP FimP PF09766.4 CDI86333.1 - 0.93 8.4 19.7 1.1 8.2 13.7 1.1 1 0 0 1 1 1 0 Fms-interacting protein IncA PF04156.9 CDI86333.1 - 0.95 9.0 17.9 0.018 14.6 7.4 1.8 2 0 0 2 2 2 0 IncA protein Med15 PF09606.5 CDI86333.1 - 1.3 7.1 53.3 1.7 6.7 37.0 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF4366 PF14283.1 CDI86333.1 - 4.1 6.7 18.0 7 6.0 12.5 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4366) OATP PF03137.15 CDI86333.1 - 5.4 4.9 8.1 5.8 4.8 5.6 1.3 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family TFIIA PF03153.8 CDI86333.1 - 6.9 6.4 43.4 7.6 6.3 30.1 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Ribosomal_60s PF00428.14 CDI86334.1 - 0.44 10.9 8.8 0.66 10.4 6.1 1.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein Zip PF02535.17 CDI86334.1 - 3.9 6.3 10.4 4.7 6.1 7.2 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Nop14 PF04147.7 CDI86335.1 - 0.00013 20.1 21.2 0.00013 20.1 14.7 3.5 3 1 0 3 3 3 1 Nop14-like family AAA_23 PF13476.1 CDI86337.1 - 0.3 11.3 5.7 0.46 10.7 4.0 1.2 1 0 0 1 1 1 0 AAA domain Tsg PF04668.7 CDI86337.1 - 0.43 10.7 4.3 1.4 9.1 0.2 2.1 2 0 0 2 2 2 0 Twisted gastrulation (Tsg) protein conserved region DUF1180 PF06679.7 CDI86337.1 - 0.55 10.1 8.5 0.029 14.2 1.9 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) DnaJ-X PF14308.1 CDI86337.1 - 1.1 8.5 12.4 0.049 12.8 2.2 2.0 2 0 0 2 2 2 0 X-domain of DnaJ-containing SAPS PF04499.10 CDI86337.1 - 2 6.9 9.0 2.5 6.6 6.2 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF3801 PF12687.2 CDI86337.1 - 3.1 7.3 13.7 5.5 6.5 9.5 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3801) DUF2052 PF09747.4 CDI86337.1 - 4.5 7.1 16.1 2.2 8.1 1.1 2.0 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) DDHD PF02862.12 CDI86337.1 - 5.8 6.6 16.3 6.5 6.4 3.8 2.0 2 0 0 2 2 2 0 DDHD domain FimP PF09766.4 CDI86338.1 - 0.0013 17.9 41.5 0.0082 15.2 12.0 2.1 2 0 0 2 2 2 2 Fms-interacting protein DUF4557 PF15101.1 CDI86338.1 - 0.0037 17.1 14.1 0.0037 17.1 9.8 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4557) zf-DHHC PF01529.15 CDI86338.1 - 0.026 13.9 12.5 0.36 10.2 1.4 2.2 2 0 0 2 2 2 0 DHHC palmitoyltransferase GAGA_bind PF06217.7 CDI86338.1 - 0.041 13.8 15.6 0.075 12.9 3.1 2.1 2 0 0 2 2 2 0 GAGA binding protein-like family SR-25 PF10500.4 CDI86338.1 - 0.056 12.9 19.1 0.011 15.2 2.7 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein EIIBC-GUT_N PF03612.9 CDI86338.1 - 0.072 12.6 18.3 0.22 11.1 4.9 2.4 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus Hid1 PF12722.2 CDI86338.1 - 0.084 10.5 17.2 0.18 9.4 4.5 2.0 2 0 0 2 2 2 0 High-temperature-induced dauer-formation protein Dala_Dala_lig_N PF01820.16 CDI86338.1 - 0.093 13.0 10.9 0.42 10.9 1.4 2.3 2 0 0 2 2 2 0 D-ala D-ala ligase N-terminus APC8 PF04049.8 CDI86338.1 - 0.13 11.9 14.7 0.11 12.2 2.4 2.2 2 0 0 2 2 2 0 Anaphase promoting complex subunit 8 / Cdc23 DUF1510 PF07423.6 CDI86338.1 - 0.18 11.1 20.5 1.1 8.5 6.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) RED_N PF07808.8 CDI86338.1 - 0.19 10.9 39.3 0.49 9.5 8.3 2.3 2 0 0 2 2 2 0 RED-like protein N-terminal region AUX_IAA PF02309.11 CDI86338.1 - 0.2 11.4 19.6 0.62 9.7 5.9 2.1 2 0 0 2 2 2 0 AUX/IAA family Folate_carrier PF01770.13 CDI86338.1 - 0.22 9.9 15.2 0.087 11.3 2.4 2.2 2 0 0 2 2 2 0 Reduced folate carrier CPSF100_C PF13299.1 CDI86338.1 - 0.22 11.6 16.0 0.62 10.2 4.0 2.2 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal DUF966 PF06136.8 CDI86338.1 - 0.23 10.8 18.0 0.46 9.8 3.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF966) FHIPEP PF00771.15 CDI86338.1 - 0.26 9.5 18.8 0.24 9.6 5.8 2.0 2 0 0 2 2 2 0 FHIPEP family FAM60A PF15396.1 CDI86338.1 - 0.31 10.7 16.1 0.59 9.8 3.7 2.2 2 0 0 2 2 2 0 Protein Family FAM60A CKAP2_C PF15297.1 CDI86338.1 - 0.39 9.4 21.5 0.76 8.5 5.6 2.1 2 0 0 2 2 2 0 Cytoskeleton-associated protein 2 C-terminus RR_TM4-6 PF06459.7 CDI86338.1 - 0.42 10.4 22.6 0.066 13.1 4.6 2.1 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Gti1_Pac2 PF09729.4 CDI86338.1 - 0.45 10.3 15.3 1 9.1 3.4 2.2 2 0 0 2 2 2 0 Gti1/Pac2 family RNA_pol_Rpc4 PF05132.9 CDI86338.1 - 0.48 10.3 18.0 1 9.3 1.4 2.2 2 0 0 2 2 2 0 RNA polymerase III RPC4 SPX PF03105.14 CDI86338.1 - 0.57 9.9 19.7 0.66 9.7 5.0 2.1 2 0 0 2 2 2 0 SPX domain Band_3_cyto PF07565.8 CDI86338.1 - 0.64 9.4 27.6 1.2 8.6 4.4 2.1 2 0 0 2 2 2 0 Band 3 cytoplasmic domain Peptidase_S49_N PF08496.5 CDI86338.1 - 0.75 9.5 22.3 2.1 8.1 5.6 2.2 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Spore_YhcN_YlaJ PF09580.5 CDI86338.1 - 0.9 9.6 19.9 1.6 8.8 4.9 2.1 2 0 0 2 2 2 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) DUF1764 PF08576.5 CDI86338.1 - 0.92 10.3 29.4 0.72 10.6 8.2 2.2 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF1764) Spore_coat_CotO PF14153.1 CDI86338.1 - 1 8.7 34.9 0.45 9.9 10.7 2.1 2 0 0 2 2 2 0 Spore coat protein CotO DUF3449 PF11931.3 CDI86338.1 - 1 8.8 19.3 1.5 8.3 4.9 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3449) BTV_NS2 PF04514.7 CDI86338.1 - 1 8.1 12.8 0.63 8.8 1.5 2.1 2 0 0 2 2 2 0 Bluetongue virus non-structural protein NS2 FLO_LFY PF01698.11 CDI86338.1 - 1.2 7.8 25.1 1.3 7.8 8.7 2.1 2 0 0 2 2 2 0 Floricaula / Leafy protein DUF4207 PF13904.1 CDI86338.1 - 1.4 8.2 49.6 1.4 8.2 12.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4207) Cyto_heme_lyase PF01265.12 CDI86338.1 - 1.4 8.4 19.8 0.25 10.8 4.8 2.1 2 0 0 2 2 2 0 Cytochrome c/c1 heme lyase BORG_CEP PF14957.1 CDI86338.1 - 2 9.3 16.8 5.7 7.8 1.7 2.3 2 0 0 2 2 2 0 Cdc42 effector DUF2203 PF09969.4 CDI86338.1 - 2 8.6 16.5 3.1 8.0 1.2 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) UPF0560 PF10577.4 CDI86338.1 - 2.2 6.4 36.4 0.38 8.9 10.3 2.0 2 0 0 2 2 2 0 Uncharacterised protein family UPF0560 PAT1 PF09770.4 CDI86338.1 - 2.3 6.3 70.2 3.1 5.9 48.7 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF3408 PF11888.3 CDI86338.1 - 2.3 8.1 23.7 4.8 7.1 7.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3408) OATP PF03137.15 CDI86338.1 - 2.6 6.0 17.9 1.6 6.6 4.5 2.1 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family PBP1_TM PF14812.1 CDI86338.1 - 2.8 8.3 14.4 2.2 8.6 2.7 2.3 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal AIF_C PF14721.1 CDI86338.1 - 3.2 7.9 22.6 1 9.6 5.6 2.4 2 0 0 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term DUF912 PF06024.7 CDI86338.1 - 3.5 7.7 19.6 0.74 9.9 0.6 2.3 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) PP_M1 PF03012.9 CDI86338.1 - 4.1 6.6 24.0 0.92 8.7 3.6 2.1 2 0 0 2 2 2 0 Phosphoprotein HD-ZIP_N PF04618.7 CDI86338.1 - 4.2 7.9 14.8 8 7.0 2.8 2.3 2 0 0 2 2 2 0 HD-ZIP protein N terminus RNA_pol_Rpb1_2 PF00623.15 CDI86338.1 - 4.3 7.2 13.7 2.7 7.9 1.5 2.2 2 0 0 2 2 2 0 RNA polymerase Rpb1, domain 2 DUF1980 PF09323.5 CDI86338.1 - 4.4 6.9 18.3 5.6 6.6 1.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) PH_4 PF15404.1 CDI86338.1 - 4.5 6.7 26.0 0.76 9.2 7.1 2.1 2 0 0 2 2 2 0 Pleckstrin homology domain Drc1-Sld2 PF11719.3 CDI86338.1 - 4.6 6.2 22.0 3 6.8 5.8 2.1 2 0 0 2 2 2 0 DNA replication and checkpoint protein FAM176 PF14851.1 CDI86338.1 - 6.4 6.4 17.1 4.7 6.8 1.7 2.2 2 0 0 2 2 2 0 FAM176 family ATAD4 PF15321.1 CDI86338.1 - 6.8 7.7 26.2 2.7 9.0 3.3 2.4 2 0 0 2 2 2 0 ATPase family AAA domain containing 4 RbsD_FucU PF05025.8 CDI86338.1 - 7.9 6.8 14.3 6.2 7.1 0.9 2.3 2 0 0 2 2 2 0 RbsD / FucU transport protein family SpoIIP PF07454.6 CDI86338.1 - 7.9 5.5 18.3 7.3 5.6 1.8 2.1 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) DHHW PF14286.1 CDI86338.1 - 8.7 5.5 16.9 0.84 8.8 3.4 2.0 2 0 0 2 2 2 0 DHHW protein Apc15p PF05841.6 CDI86338.1 - 9.3 7.0 32.0 1.9 9.1 6.8 3.1 3 0 0 3 3 3 0 Apc15p protein Hom_end_hint PF05203.11 CDI86338.1 - 9.6 5.8 16.0 7.5 6.2 1.5 2.2 2 0 0 2 2 2 0 Hom_end-associated Hint Big_2 PF02368.13 CDI86339.1 - 0.0012 18.6 4.5 0.0018 18.1 3.1 1.4 1 0 0 1 1 1 1 Bacterial Ig-like domain (group 2) DUF4246 PF14033.1 CDI86339.1 - 0.003 16.2 3.8 0.0034 16.0 2.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) APCDDC PF14921.1 CDI86339.1 - 0.036 13.4 4.5 0.056 12.7 3.1 1.2 1 0 0 1 1 1 0 Adenomatosis polyposis coli down-regulated 1 CDK2AP PF09806.4 CDI86339.1 - 0.053 13.7 13.1 0.061 13.5 9.1 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein DUF2459 PF09601.5 CDI86339.1 - 0.073 12.7 1.2 0.11 12.1 0.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2459) PhoQ_Sensor PF08918.5 CDI86339.1 - 0.094 12.2 0.6 0.14 11.6 0.4 1.3 1 0 0 1 1 1 0 PhoQ Sensor KAR9 PF08580.5 CDI86339.1 - 0.14 10.4 4.7 0.15 10.3 3.3 1.0 1 0 0 1 1 1 0 Yeast cortical protein KAR9 APC_CDC26 PF10471.4 CDI86339.1 - 0.18 12.5 19.6 0.74 10.5 7.6 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit 1 Pup PF05639.6 CDI86339.1 - 0.48 10.9 0.1 0.48 10.9 0.1 2.3 1 1 0 2 2 2 0 Pup-like protein Mucin PF01456.12 CDI86339.1 - 0.52 10.0 9.4 0.6 9.8 6.5 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein GAGA_bind PF06217.7 CDI86339.1 - 0.62 9.9 9.3 0.72 9.7 6.4 1.0 1 0 0 1 1 1 0 GAGA binding protein-like family DUF966 PF06136.8 CDI86339.1 - 1.1 8.6 13.4 1.2 8.5 9.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Neur_chan_memb PF02932.11 CDI86339.1 - 1.6 8.5 5.6 1.8 8.3 3.9 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region UCH PF00443.24 CDI86339.1 - 2.1 7.4 6.5 2.2 7.3 4.5 1.1 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase DUF3138 PF11336.3 CDI86339.1 - 2.7 6.0 16.0 3.4 5.7 11.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) DUF2489 PF10675.4 CDI86339.1 - 3 7.5 18.7 1 9.0 5.7 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2489) FLO_LFY PF01698.11 CDI86339.1 - 4 6.1 8.2 4.5 6.0 5.7 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein Lin-8 PF03353.10 CDI86339.1 - 4.1 6.5 11.8 5.5 6.1 8.2 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist DUF4647 PF15504.1 CDI86339.1 - 5.5 5.7 15.2 7.7 5.2 10.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4647) FAM60A PF15396.1 CDI86339.1 - 6.6 6.4 8.5 9.3 5.9 5.9 1.2 1 0 0 1 1 1 0 Protein Family FAM60A TFIIA PF03153.8 CDI86339.1 - 7.9 6.2 18.7 11 5.7 13.0 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Conotoxin PF02950.12 CDI86339.1 - 8.1 7.3 7.6 17 6.2 0.3 2.2 2 0 0 2 2 2 0 Conotoxin Zip PF02535.17 CDI86340.1 - 0.0015 17.6 3.7 0.0016 17.4 2.6 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter TRAP_alpha PF03896.11 CDI86340.1 - 0.0016 17.5 6.1 0.0017 17.4 4.2 1.1 1 0 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit SpoIIIAH PF12685.2 CDI86340.1 - 0.0078 15.7 18.2 0.0094 15.4 12.6 1.0 1 0 0 1 1 1 1 SpoIIIAH-like protein DUF1510 PF07423.6 CDI86340.1 - 0.016 14.6 27.4 0.02 14.2 19.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) SID-1_RNA_chan PF13965.1 CDI86340.1 - 0.065 11.3 14.0 0.071 11.2 9.7 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DUF4131 PF13567.1 CDI86340.1 - 0.092 12.1 13.2 0.11 11.9 9.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) NPR3 PF03666.8 CDI86340.1 - 0.19 10.2 21.5 0.22 10.0 14.9 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 CDC45 PF02724.9 CDI86340.1 - 0.29 9.1 26.9 0.35 8.8 18.6 1.0 1 0 0 1 1 1 0 CDC45-like protein Ycf1 PF05758.7 CDI86340.1 - 0.31 8.7 25.0 0.34 8.5 17.3 1.0 1 0 0 1 1 1 0 Ycf1 TerC PF03741.11 CDI86340.1 - 0.33 10.3 2.5 0.61 9.5 1.8 1.7 1 1 0 1 1 1 0 Integral membrane protein TerC family Neur_chan_memb PF02932.11 CDI86340.1 - 0.71 9.7 14.3 0.84 9.4 9.9 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Paramyxo_ncap PF00973.14 CDI86340.1 - 1.1 7.9 20.8 1.2 7.7 14.4 1.0 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein K_trans PF02705.11 CDI86340.1 - 1.4 7.1 7.6 1.8 6.7 5.3 1.2 1 0 0 1 1 1 0 K+ potassium transporter OAD_gamma PF04277.8 CDI86340.1 - 1.5 9.2 6.2 9.1 6.7 4.3 2.2 1 1 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain Presenilin PF01080.12 CDI86340.1 - 1.8 7.3 14.6 2.1 7.0 10.2 1.0 1 0 0 1 1 1 0 Presenilin AMP-binding PF00501.23 CDI86340.1 - 2.7 6.2 6.4 3.3 5.9 4.4 1.2 1 0 0 1 1 1 0 AMP-binding enzyme DUF2852 PF11014.3 CDI86340.1 - 3.3 7.6 12.5 4.5 7.2 8.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2852) DHHW PF14286.1 CDI86340.1 - 3.3 6.9 17.7 3.9 6.7 12.3 1.1 1 0 0 1 1 1 0 DHHW protein PA26 PF04636.8 CDI86340.1 - 3.3 6.2 15.1 3.6 6.1 10.5 1.0 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) CD20 PF04103.10 CDI86340.1 - 4.1 7.3 11.1 47 3.8 7.7 2.1 1 1 0 1 1 1 0 CD20-like family Raftlin PF15250.1 CDI86340.1 - 4.3 5.7 23.8 5.2 5.4 16.5 1.0 1 0 0 1 1 1 0 Raftlin FAM60A PF15396.1 CDI86340.1 - 5.4 6.6 22.9 6.2 6.5 15.9 1.0 1 0 0 1 1 1 0 Protein Family FAM60A DUF913 PF06025.7 CDI86340.1 - 5.7 5.5 13.7 7.5 5.1 9.5 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Mem_trans PF03547.13 CDI86340.1 - 6.1 5.0 10.8 7.2 4.7 7.5 1.2 1 0 0 1 1 1 0 Membrane transport protein FHIPEP PF00771.15 CDI86340.1 - 8.6 4.5 23.4 15 3.7 16.2 1.4 1 1 0 1 1 1 0 FHIPEP family Rtf2 PF04641.7 CDI86340.1 - 8.6 5.4 27.1 11 5.1 18.8 1.0 1 0 0 1 1 1 0 Rtf2 RING-finger Dicty_REP PF05086.7 CDI86340.1 - 8.7 3.9 13.3 9.6 3.8 9.3 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Parvo_coat PF00740.13 CDI86340.1 - 9.4 5.0 25.7 11 4.8 17.8 1.0 1 0 0 1 1 1 0 Parvovirus coat protein VP2 FCP1_C PF09309.5 CDI86341.1 - 0.00019 20.8 6.5 0.00024 20.4 4.5 1.1 1 0 0 1 1 1 1 FCP1, C-terminal Med15 PF09606.5 CDI86341.1 - 0.0033 15.7 20.5 0.003 15.8 14.2 1.1 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal DnaJ-X PF14308.1 CDI86341.1 - 0.049 12.8 4.2 0.048 12.9 2.9 1.2 1 0 0 1 1 1 0 X-domain of DnaJ-containing Peptidase_M56 PF05569.6 CDI86341.1 - 0.095 11.6 1.5 0.099 11.5 1.0 1.0 1 0 0 1 1 1 0 BlaR1 peptidase M56 BAF1_ABF1 PF04684.8 CDI86341.1 - 0.13 11.0 15.2 0.12 11.1 10.5 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor DUF912 PF06024.7 CDI86341.1 - 0.15 12.0 7.5 0.13 12.2 1.7 2.0 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) CDK2AP PF09806.4 CDI86341.1 - 0.17 12.1 11.6 0.26 11.5 8.0 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein Trs65 PF12735.2 CDI86341.1 - 0.35 10.1 10.1 0.39 9.9 7.0 1.0 1 0 0 1 1 1 0 TRAPP trafficking subunit Trs65 MFS_Mycoplasma PF07672.8 CDI86341.1 - 0.54 9.3 1.8 0.59 9.2 1.3 1.0 1 0 0 1 1 1 0 Mycoplasma MFS transporter MMR1 PF08505.5 CDI86341.1 - 0.67 9.9 15.4 0.85 9.6 10.7 1.2 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein SPT16 PF08644.6 CDI86341.1 - 0.75 9.6 6.0 1.3 8.8 4.2 1.3 1 0 0 1 1 1 0 FACT complex subunit (SPT16/CDC68) Spc7_N PF15402.1 CDI86341.1 - 0.79 7.6 10.0 0.95 7.3 6.9 1.0 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 DUF4175 PF13779.1 CDI86341.1 - 1.1 6.9 22.3 1.4 6.5 15.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Secretin_N_2 PF07655.8 CDI86341.1 - 1.1 9.6 19.1 0.96 9.8 7.3 2.1 2 0 0 2 2 2 0 Secretin N-terminal domain Neur_chan_memb PF02932.11 CDI86341.1 - 1.5 8.6 8.8 1.6 8.5 6.1 1.0 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Rot1 PF10681.4 CDI86341.1 - 2.3 7.4 9.1 0.39 10.0 3.9 1.5 1 1 1 2 2 2 0 Chaperone for protein-folding within the ER, fungal SDP_N PF12278.3 CDI86341.1 - 2.8 7.5 7.9 3.5 7.2 5.5 1.1 1 0 0 1 1 1 0 Sex determination protein N terminal Kei1 PF08552.6 CDI86341.1 - 2.9 7.5 9.1 0.11 12.1 1.4 1.8 1 1 1 2 2 2 0 Inositolphosphorylceramide synthase subunit Kei1 DUF4199 PF13858.1 CDI86341.1 - 3.3 7.6 6.6 5 7.0 4.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) Peptidase_S49_N PF08496.5 CDI86341.1 - 3.4 7.4 6.9 0.42 10.3 2.3 1.4 2 0 0 2 2 1 0 Peptidase family S49 N-terminal Presenilin PF01080.12 CDI86341.1 - 3.5 6.3 7.1 4 6.1 4.9 1.1 1 0 0 1 1 1 0 Presenilin DUF4643 PF15485.1 CDI86341.1 - 3.9 6.8 11.7 4.2 6.7 7.7 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4643) DUF4407 PF14362.1 CDI86341.1 - 4.4 6.1 8.1 5.7 5.8 5.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) HlyD_2 PF12700.2 CDI86341.1 - 6.2 5.8 10.0 7.8 5.5 6.9 1.1 1 0 0 1 1 1 0 HlyD family secretion protein DivIC PF04977.10 CDI86341.1 - 7.1 6.1 16.9 11 5.5 11.7 1.3 1 0 0 1 1 1 0 Septum formation initiator Exonuc_VII_L PF02601.10 CDI86341.1 - 8.8 5.4 11.0 11 5.1 7.6 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit LCD1 PF09798.4 CDI86341.1 - 9.6 4.0 12.0 10 3.9 8.3 1.1 1 0 0 1 1 1 0 DNA damage checkpoint protein Spt20 PF12090.3 CDI86342.1 - 0.48 9.7 5.0 7.2 5.9 3.3 2.2 2 0 0 2 2 2 0 Spt20 family MACPF PF01823.14 CDI86342.1 - 0.81 9.3 4.8 1.3 8.6 3.3 1.2 1 0 0 1 1 1 0 MAC/Perforin domain DUF2244 PF10003.4 CDI86343.1 - 0.13 11.6 0.1 0.13 11.6 0.1 2.5 3 1 0 3 3 3 0 Integral membrane protein (DUF2244) FA_hydroxylase PF04116.8 CDI86343.1 - 0.59 10.5 8.4 1.8 9.0 1.2 2.4 2 0 0 2 2 2 0 Fatty acid hydroxylase superfamily SR-25 PF10500.4 CDI86344.1 - 0.054 12.9 29.1 0.067 12.6 20.2 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein ORC6 PF05460.8 CDI86344.1 - 1.9 7.5 16.7 2 7.4 11.6 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) RAP1 PF07218.6 CDI86344.1 - 6 4.8 11.4 5.8 4.8 7.9 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) SURF6 PF04935.7 CDI86344.1 - 6.2 6.0 23.5 6.9 5.8 16.3 1.1 1 0 0 1 1 1 0 Surfeit locus protein 6 DUF4636 PF15468.1 CDI86344.1 - 10 5.5 20.0 11 5.3 13.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4636) Pkinase PF00069.20 CDI86345.1 - 0.014 14.5 0.0 0.027 13.6 0.0 1.4 1 0 0 1 1 1 0 Protein kinase domain Pex14_N PF04695.8 CDI86346.1 - 0.39 10.7 7.1 0.49 10.4 4.9 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF3399 PF11879.3 CDI86346.1 - 0.52 10.5 5.4 0.57 10.4 3.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3399) CAF-1_p150 PF11600.3 CDI86346.1 - 0.99 8.7 8.3 1 8.7 5.8 1.0 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Apc15p PF05841.6 CDI86346.1 - 1.6 9.4 6.3 1.8 9.3 4.3 1.1 1 0 0 1 1 1 0 Apc15p protein Senescence_reg PF04520.8 CDI86346.1 - 2.8 8.4 5.5 2.9 8.3 3.8 1.0 1 0 0 1 1 1 0 Senescence regulator Corona_nucleoca PF00937.13 CDI86346.1 - 3 6.6 8.8 3 6.7 6.1 1.0 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein Secretin_N_2 PF07655.8 CDI86346.1 - 3.6 8.0 15.2 4.7 7.6 10.5 1.1 1 0 0 1 1 1 0 Secretin N-terminal domain Period_C PF12114.3 CDI86346.1 - 4.4 6.8 10.2 4.7 6.7 7.1 1.1 1 0 0 1 1 1 0 Period protein 2/3C-terminal region Rifin_STEVOR PF02009.11 CDI86346.1 - 8.3 5.9 10.6 8.6 5.9 7.3 1.0 1 0 0 1 1 1 0 Rifin/stevor family Peptidase_C97 PF05903.9 CDI86347.1 - 2.7e-17 62.9 0.0 8.4e-17 61.3 0.0 1.7 1 0 0 1 1 1 1 PPPDE putative peptidase domain TPR_11 PF13414.1 CDI86348.1 - 3.1e-09 36.3 8.3 2.1e-06 27.3 1.5 2.5 2 0 0 2 2 2 2 TPR repeat TPR_1 PF00515.23 CDI86348.1 - 1.4e-05 24.4 7.5 0.0001 21.7 0.1 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 CDI86348.1 - 2.8e-05 23.6 8.5 7.1e-05 22.4 0.1 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 CDI86348.1 - 5.8e-05 22.9 7.4 0.0014 18.5 0.9 3.0 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.1 CDI86348.1 - 0.0015 19.1 1.2 0.0015 19.1 0.8 3.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.1 CDI86348.1 - 0.02 14.8 1.2 0.02 14.8 0.8 3.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.1 CDI86348.1 - 0.024 14.4 3.3 0.094 12.5 0.1 2.7 2 1 0 2 2 2 0 Tetratricopeptide repeat PAT1 PF09770.4 CDI86349.1 - 2 6.5 71.8 2.2 6.4 49.7 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Med15 PF09606.5 CDI86350.1 - 0.00085 17.6 49.1 0.00095 17.5 34.0 1.1 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal PAT1 PF09770.4 CDI86350.1 - 0.0013 17.0 35.0 0.0013 17.0 24.3 1.1 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 Spc7_N PF15402.1 CDI86350.1 - 0.0031 15.6 14.3 0.0036 15.3 9.9 1.0 1 0 0 1 1 1 1 N-terminus of kinetochore NMS complex subunit Spc7 TFIIA PF03153.8 CDI86350.1 - 0.0036 17.2 25.6 0.0042 17.0 17.8 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit SAGA-Tad1 PF12767.2 CDI86350.1 - 0.0055 16.4 13.8 0.0067 16.1 9.6 1.2 1 0 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit Med19 PF10278.4 CDI86350.1 - 0.0063 16.2 4.2 0.008 15.8 2.9 1.1 1 0 0 1 1 1 1 Mediator of RNA pol II transcription subunit 19 Presenilin PF01080.12 CDI86350.1 - 0.014 14.2 3.0 0.014 14.2 2.1 1.1 1 0 0 1 1 1 0 Presenilin Hamartin PF04388.7 CDI86350.1 - 0.017 13.7 7.4 0.019 13.7 5.1 1.2 1 0 0 1 1 1 0 Hamartin protein Peptidase_S15 PF02129.13 CDI86350.1 - 0.047 13.0 7.2 0.061 12.7 5.0 1.4 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Ycf1 PF05758.7 CDI86350.1 - 0.057 11.1 11.5 0.065 10.9 8.0 1.0 1 0 0 1 1 1 0 Ycf1 NARP1 PF12569.3 CDI86350.1 - 0.058 12.1 14.3 0.074 11.7 9.9 1.3 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 PPP4R2 PF09184.6 CDI86350.1 - 0.076 12.5 10.7 0.09 12.3 7.4 1.1 1 0 0 1 1 1 0 PPP4R2 AIF_C PF14721.1 CDI86350.1 - 0.083 13.1 9.7 0.13 12.4 6.7 1.4 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term DUF4175 PF13779.1 CDI86350.1 - 0.14 9.8 48.2 0.19 9.4 33.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) DDHD PF02862.12 CDI86350.1 - 0.14 11.9 14.6 0.18 11.5 10.1 1.1 1 0 0 1 1 1 0 DDHD domain Pex14_N PF04695.8 CDI86350.1 - 0.19 11.7 24.3 0.02 14.9 13.6 1.8 2 0 0 2 2 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region MMR1 PF08505.5 CDI86350.1 - 0.2 11.6 17.9 0.23 11.4 12.4 1.2 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein RR_TM4-6 PF06459.7 CDI86350.1 - 0.2 11.4 14.6 0.27 11.0 10.1 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF605 PF04652.11 CDI86350.1 - 0.21 10.9 23.8 0.24 10.7 16.5 1.1 1 0 0 1 1 1 0 Vta1 like Cellulose_synt PF03552.9 CDI86350.1 - 0.22 9.7 3.0 0.24 9.6 2.1 1.0 1 0 0 1 1 1 0 Cellulose synthase Pal1 PF08316.6 CDI86350.1 - 0.26 11.7 7.1 0.41 11.0 4.9 1.3 1 0 0 1 1 1 0 Pal1 cell morphology protein SeqA PF03925.8 CDI86350.1 - 0.27 10.9 13.1 0.36 10.5 9.1 1.2 1 0 0 1 1 1 0 SeqA protein DHHW PF14286.1 CDI86350.1 - 0.28 10.4 9.9 0.32 10.2 6.8 1.1 1 0 0 1 1 1 0 DHHW protein UPF0560 PF10577.4 CDI86350.1 - 0.32 9.2 21.8 0.37 8.9 15.1 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Spore_coat_CotO PF14153.1 CDI86350.1 - 0.34 10.3 23.3 0.45 9.9 16.1 1.1 1 0 0 1 1 1 0 Spore coat protein CotO Zip PF02535.17 CDI86350.1 - 0.36 9.7 5.2 0.54 9.2 3.6 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter Hid1 PF12722.2 CDI86350.1 - 0.38 8.3 16.2 0.43 8.1 11.2 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Raftlin PF15250.1 CDI86350.1 - 0.38 9.2 13.6 0.44 9.0 9.4 1.1 1 0 0 1 1 1 0 Raftlin AUX_IAA PF02309.11 CDI86350.1 - 0.42 10.3 11.9 0.52 10.0 8.3 1.1 1 0 0 1 1 1 0 AUX/IAA family YABBY PF04690.8 CDI86350.1 - 0.46 10.7 8.7 0.65 10.2 6.0 1.2 1 0 0 1 1 1 0 YABBY protein AAA_23 PF13476.1 CDI86350.1 - 0.49 10.6 15.4 0.59 10.4 10.7 1.1 1 0 0 1 1 1 0 AAA domain DUF4557 PF15101.1 CDI86350.1 - 0.52 10.1 26.1 0.76 9.5 18.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) BTV_NS2 PF04514.7 CDI86350.1 - 0.53 9.1 12.2 0.63 8.8 8.4 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 FAM60A PF15396.1 CDI86350.1 - 0.62 9.7 12.4 0.83 9.3 8.6 1.1 1 0 0 1 1 1 0 Protein Family FAM60A FliP PF00813.15 CDI86350.1 - 0.74 9.4 5.5 1.2 8.7 3.8 1.4 1 0 0 1 1 1 0 FliP family CDK5_activator PF03261.10 CDI86350.1 - 0.91 8.7 15.9 1.2 8.4 11.0 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein Pox_P4B PF03292.9 CDI86350.1 - 0.99 7.2 6.5 1.1 7.0 4.5 1.1 1 0 0 1 1 1 0 Poxvirus P4B major core protein DUF853 PF05872.7 CDI86350.1 - 1 7.6 12.3 1.3 7.3 8.5 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) Neur_chan_memb PF02932.11 CDI86350.1 - 1.3 8.8 11.1 1.9 8.2 7.7 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF2126 PF09899.4 CDI86350.1 - 1.4 6.9 10.1 1.6 6.6 7.0 1.1 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) DUF1510 PF07423.6 CDI86350.1 - 1.8 7.8 19.4 2.5 7.3 13.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) CRF1 PF10380.4 CDI86350.1 - 1.8 8.8 7.3 4.1 7.7 5.1 1.6 1 0 0 1 1 1 0 Transcription factor CRF1 Paramyxo_ncap PF00973.14 CDI86350.1 - 1.9 7.1 14.0 2.3 6.8 9.7 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein FLO_LFY PF01698.11 CDI86350.1 - 2 7.1 17.1 2.7 6.7 11.9 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein Anoctamin PF04547.7 CDI86350.1 - 2.8 6.4 6.0 3.3 6.2 4.2 1.2 1 0 0 1 1 1 0 Calcium-activated chloride channel Herpes_DNAp_acc PF04929.7 CDI86350.1 - 3 6.7 12.8 4 6.2 8.8 1.2 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Plasmodium_Vir PF05795.6 CDI86350.1 - 3.6 6.7 4.9 4.3 6.4 3.4 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Band_3_cyto PF07565.8 CDI86350.1 - 4.2 6.8 17.2 6.2 6.2 11.9 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain SID-1_RNA_chan PF13965.1 CDI86350.1 - 4.2 5.4 8.2 5.2 5.1 5.7 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 SAPS PF04499.10 CDI86350.1 - 5.9 5.4 15.2 7.2 5.1 10.5 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF1980 PF09323.5 CDI86350.1 - 7.5 6.2 10.0 11 5.7 6.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) RIC3 PF15361.1 CDI86350.1 - 8.6 6.5 19.1 16 5.7 13.2 1.5 1 0 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 DUF2828 PF11443.3 CDI86350.1 - 9.5 4.2 14.4 12 3.9 10.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Lin-8 PF03353.10 CDI86350.1 - 10 5.3 21.1 13 4.9 14.6 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Rifin_STEVOR PF02009.11 CDI86351.1 - 0.007 16.0 6.2 0.007 16.0 4.3 3.3 1 1 1 3 3 3 1 Rifin/stevor family Claudin_2 PF13903.1 CDI86351.1 - 0.011 15.4 6.6 0.31 10.7 0.0 3.4 3 0 0 3 3 3 0 PMP-22/EMP/MP20/Claudin tight junction FA_desaturase PF00487.19 CDI86351.1 - 0.16 11.3 0.1 11 5.3 0.3 2.3 2 0 0 2 2 2 0 Fatty acid desaturase Pkinase PF00069.20 CDI86352.1 - 5.7e-22 78.1 0.1 6.4e-16 58.2 0.1 3.5 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.12 CDI86352.1 - 1.2e-07 31.1 0.2 0.0013 17.8 0.0 3.6 2 2 0 2 2 2 2 Protein tyrosine kinase Med15 PF09606.5 CDI86352.1 - 0.0014 16.9 34.4 0.0014 16.9 23.8 5.8 3 1 3 6 6 6 2 ARC105 or Med15 subunit of Mediator complex non-fungal COQ7 PF03232.8 CDI86353.1 - 0.14 11.6 0.6 0.2 11.1 0.4 1.1 1 0 0 1 1 1 0 Ubiquinone biosynthesis protein COQ7 DUF1777 PF08648.7 CDI86355.1 - 7.6e-09 35.5 22.9 7.6e-09 35.5 15.9 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1777) MIP-T3 PF10243.4 CDI86355.1 - 5 5.4 27.2 7.4 4.9 18.9 1.3 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Neur_chan_memb PF02932.11 CDI86356.1 - 0.003 17.5 2.0 0.0049 16.7 1.4 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Trp_oprn_chp PF09534.5 CDI86356.1 - 0.004 16.7 27.9 0.0053 16.3 19.4 1.3 1 0 0 1 1 1 1 Tryptophan-associated transmembrane protein (Trp_oprn_chp) EURL PF06937.6 CDI86356.1 - 0.065 12.6 7.2 0.071 12.5 5.0 1.1 1 0 0 1 1 1 0 EURL protein DUF1510 PF07423.6 CDI86356.1 - 0.086 12.2 15.4 0.19 11.0 0.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) DUF4207 PF13904.1 CDI86356.1 - 0.11 11.8 17.5 0.15 11.3 12.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4207) DDHD PF02862.12 CDI86356.1 - 0.13 11.9 5.9 0.18 11.6 4.1 1.1 1 0 0 1 1 1 0 DDHD domain SoxE PF06525.6 CDI86356.1 - 0.15 11.3 2.5 0.19 11.0 1.7 1.2 1 0 0 1 1 1 0 Sulfocyanin (SoxE) CCDC84 PF14968.1 CDI86356.1 - 0.23 10.9 9.2 0.27 10.6 6.4 1.0 1 0 0 1 1 1 0 Coiled coil protein 84 DUF812 PF05667.6 CDI86356.1 - 0.24 9.8 12.3 0.29 9.5 8.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF812) PRA1 PF03208.14 CDI86356.1 - 0.35 10.1 4.0 0.63 9.3 2.8 1.4 1 0 0 1 1 1 0 PRA1 family protein Med15 PF09606.5 CDI86356.1 - 0.48 8.5 27.0 0.54 8.3 18.7 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Silic_transp PF03842.8 CDI86356.1 - 0.9 7.5 4.9 1.1 7.2 3.4 1.0 1 0 0 1 1 1 0 Silicon transporter TFIIA PF03153.8 CDI86356.1 - 0.93 9.3 18.9 1.1 9.0 13.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Peptidase_S49_N PF08496.5 CDI86356.1 - 0.99 9.1 13.9 0.3 10.8 0.6 2.2 2 0 0 2 2 2 0 Peptidase family S49 N-terminal R_equi_Vir PF05526.6 CDI86356.1 - 3.5 7.2 23.0 1.5 8.3 5.1 2.1 1 1 1 2 2 2 0 Rhodococcus equi virulence-associated protein FAM176 PF14851.1 CDI86356.1 - 3.6 7.2 8.1 30 4.2 4.0 2.1 2 0 0 2 2 2 0 FAM176 family RskA PF10099.4 CDI86356.1 - 3.6 7.2 41.5 2.9 7.6 11.8 2.2 1 1 1 2 2 2 0 Anti-sigma-K factor rskA DUF4179 PF13786.1 CDI86356.1 - 5.6 7.2 18.7 0.63 10.3 0.4 3.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4179) PAT1 PF09770.4 CDI86356.1 - 6 4.9 22.5 7 4.7 15.6 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Gly-zipper_OmpA PF13436.1 CDI86357.1 - 0.0013 18.3 19.4 0.0017 17.9 13.5 1.1 1 0 0 1 1 1 1 Glycine-zipper containing OmpA-like membrane domain DUF677 PF05055.7 CDI86357.1 - 0.0026 16.4 1.3 0.0031 16.2 0.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF677) Shadoo PF14999.1 CDI86357.1 - 0.058 13.2 5.9 0.073 12.9 4.1 1.1 1 0 0 1 1 1 0 Shadow of prion protein, neuroprotective FAM60A PF15396.1 CDI86357.1 - 0.95 9.1 12.2 1.3 8.7 8.4 1.2 1 0 0 1 1 1 0 Protein Family FAM60A NapE PF06796.6 CDI86357.1 - 1.1 8.6 0.0 1.1 8.6 0.0 2.4 3 1 0 3 3 3 0 Periplasmic nitrate reductase protein NapE DUF4613 PF15390.1 CDI86357.1 - 1.2 7.2 15.3 1.4 7.0 10.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) Senescence_reg PF04520.8 CDI86357.1 - 3.5 8.1 12.5 4.5 7.7 8.7 1.2 1 0 0 1 1 1 0 Senescence regulator SAPS PF04499.10 CDI86357.1 - 6.2 5.3 13.8 7.4 5.0 9.6 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein tRNA_synt_1c_R2 PF04557.10 CDI86357.1 - 7.5 7.3 15.0 2.7e+02 2.3 10.4 2.3 1 1 0 1 1 1 0 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 Hid1 PF12722.2 CDI86357.1 - 8.9 3.8 18.9 10 3.6 13.1 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF3632 PF12311.3 CDI86358.1 - 0.11 12.3 4.6 0.14 11.9 3.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3632) Caldesmon PF02029.10 CDI86358.1 - 4.3 5.6 15.7 28 2.9 10.4 1.9 1 1 0 1 1 1 0 Caldesmon SseC PF04888.7 CDI86359.1 - 0.0035 16.7 33.6 0.0035 16.7 23.3 13.1 9 2 1 11 11 11 3 Secretion system effector C (SseC) like family SR-25 PF10500.4 CDI86360.1 - 0.012 15.0 32.9 0.022 14.2 22.7 1.4 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF1777 PF08648.7 CDI86360.1 - 0.048 13.3 10.9 0.064 12.9 7.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) SPX PF03105.14 CDI86360.1 - 0.077 12.7 19.4 0.093 12.4 13.5 1.1 1 0 0 1 1 1 0 SPX domain DUF45 PF01863.12 CDI86360.1 - 0.82 9.4 12.9 1 9.1 8.9 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF45 Pex16 PF08610.5 CDI86360.1 - 1.7 7.6 19.1 2 7.3 13.2 1.1 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) Activator_LAG-3 PF11498.3 CDI86360.1 - 2.2 6.9 56.5 0.44 9.2 11.2 2.2 2 0 0 2 2 2 0 Transcriptional activator LAG-3 PAT1 PF09770.4 CDI86360.1 - 2.3 6.3 46.9 2.6 6.1 32.5 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF4647 PF15504.1 CDI86360.1 - 2.5 6.8 25.8 3.1 6.5 17.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4647) DUF2217 PF10265.4 CDI86360.1 - 2.6 6.7 19.6 3.4 6.3 13.6 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) PLRV_ORF5 PF01690.12 CDI86360.1 - 2.9 6.9 22.0 3.4 6.7 15.3 1.0 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein DUF572 PF04502.8 CDI86360.1 - 2.9 7.0 25.8 3.9 6.6 17.9 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Mem_trans PF03547.13 CDI86360.1 - 3.3 5.9 10.7 4.7 5.3 7.4 1.4 1 0 0 1 1 1 0 Membrane transport protein DUF4603 PF15376.1 CDI86360.1 - 3.4 4.7 18.2 4 4.5 12.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) DUF2146 PF10220.4 CDI86360.1 - 3.8 5.3 21.5 4.5 5.1 14.9 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2146) DUF1675 PF07897.6 CDI86360.1 - 4.2 7.1 21.5 5.2 6.8 14.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) SOBP PF15279.1 CDI86360.1 - 4.7 7.4 21.7 7 6.9 15.0 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein Bud13 PF09736.4 CDI86360.1 - 5.9 7.1 23.7 3 8.0 3.9 2.1 2 0 0 2 2 2 0 Pre-mRNA-splicing factor of RES complex DUF4551 PF15087.1 CDI86360.1 - 6.8 4.9 24.6 8.4 4.6 17.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) CAF-1_p150 PF11600.3 CDI86361.1 - 0.011 15.1 41.5 0.014 14.7 28.8 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal CDC27 PF09507.5 CDI86361.1 - 0.12 11.5 37.7 0.15 11.2 26.2 1.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Macoilin PF09726.4 CDI86361.1 - 1.4 7.1 32.4 1.9 6.6 22.5 1.2 1 0 0 1 1 1 0 Transmembrane protein TAF1D PF15333.1 CDI86361.1 - 1.7 8.3 20.1 2.6 7.7 14.0 1.4 1 0 0 1 1 1 0 TATA box-binding protein-associated factor 1D Neugrin PF06413.6 CDI86361.1 - 2.3 7.9 15.8 2.8 7.6 11.0 1.2 1 0 0 1 1 1 0 Neugrin PPP4R2 PF09184.6 CDI86361.1 - 8.5 5.8 35.1 11 5.5 24.3 1.1 1 0 0 1 1 1 0 PPP4R2 CytochromB561_N PF09786.4 CDI86361.1 - 8.9 4.6 26.2 11 4.3 18.2 1.0 1 0 0 1 1 1 0 Cytochrome B561, N terminal Etmic-2 PF06670.6 CDI86362.1 - 2.3e-56 191.1 12.3 8.6e-36 123.4 2.4 2.0 1 1 1 2 2 2 2 Microneme protein Etmic-2 DUF620 PF04788.7 CDI86363.1 - 0.11 11.5 0.8 0.22 10.6 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF620) SMN PF06003.7 CDI86365.1 - 0.058 12.4 4.1 0.065 12.3 2.9 1.0 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) DUF2076 PF09849.4 CDI86365.1 - 0.078 13.0 14.9 0.081 12.9 10.3 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) DUF4569 PF15133.1 CDI86365.1 - 0.12 11.8 10.9 0.12 11.7 7.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4569) NARP1 PF12569.3 CDI86365.1 - 0.16 10.6 8.8 0.16 10.6 6.1 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 ATG22 PF11700.3 CDI86365.1 - 0.31 9.4 2.4 0.37 9.2 1.6 1.0 1 0 0 1 1 1 0 Vacuole effluxer Atg22 like Zip PF02535.17 CDI86365.1 - 0.32 9.9 8.5 0.3 10.0 5.9 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter SprA-related PF12118.3 CDI86365.1 - 0.34 10.1 24.7 0.34 10.1 17.1 1.0 1 0 0 1 1 1 0 SprA-related family FimP PF09766.4 CDI86365.1 - 0.36 9.8 17.7 0.39 9.7 12.3 1.1 1 0 0 1 1 1 0 Fms-interacting protein AIF_C PF14721.1 CDI86365.1 - 0.36 11.0 7.3 0.38 10.9 5.1 1.1 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Oleosin PF01277.12 CDI86365.1 - 0.44 10.1 4.0 0.51 9.9 2.8 1.1 1 0 0 1 1 1 0 Oleosin Spore_coat_CotO PF14153.1 CDI86365.1 - 0.51 9.7 14.0 0.54 9.6 9.7 1.1 1 0 0 1 1 1 0 Spore coat protein CotO SspB PF04386.8 CDI86365.1 - 0.51 9.9 9.2 0.63 9.6 6.4 1.1 1 0 0 1 1 1 0 Stringent starvation protein B DUF2098 PF09871.4 CDI86365.1 - 0.56 10.1 4.2 0.6 10.0 2.9 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2098) Peptidase_U57 PF05582.7 CDI86365.1 - 0.58 9.0 6.2 0.58 9.0 4.3 1.0 1 0 0 1 1 1 0 YabG peptidase U57 SelP_N PF04592.9 CDI86365.1 - 0.69 9.2 11.9 0.72 9.1 8.2 1.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region UPF0560 PF10577.4 CDI86365.1 - 0.84 7.8 18.8 0.87 7.7 13.1 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 DUF4094 PF13334.1 CDI86365.1 - 0.88 9.9 7.6 1.3 9.4 5.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4094) DUF1764 PF08576.5 CDI86365.1 - 0.94 10.2 12.8 1.2 9.9 8.9 1.1 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) RIC3 PF15361.1 CDI86365.1 - 0.94 9.7 9.1 0.93 9.7 6.3 1.1 1 0 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 DUF2048 PF09752.4 CDI86365.1 - 1.1 8.0 5.3 1.2 7.9 3.7 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2048) Paf1 PF03985.8 CDI86365.1 - 1.2 7.8 14.3 1.2 7.8 9.9 1.1 1 0 0 1 1 1 0 Paf1 AUX_IAA PF02309.11 CDI86365.1 - 1.2 8.8 8.2 1.3 8.7 5.7 1.1 1 0 0 1 1 1 0 AUX/IAA family RR_TM4-6 PF06459.7 CDI86365.1 - 1.3 8.9 10.7 1.3 8.8 7.4 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 G0-G1_switch_2 PF15103.1 CDI86365.1 - 1.3 9.3 5.9 1.7 8.9 4.1 1.3 1 0 0 1 1 1 0 G0/G1 switch protein 2 DUF3395 PF11875.3 CDI86365.1 - 1.3 8.6 13.2 1.6 8.3 9.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3395) Folate_carrier PF01770.13 CDI86365.1 - 1.4 7.3 6.3 1.5 7.2 4.4 1.0 1 0 0 1 1 1 0 Reduced folate carrier Ycf1 PF05758.7 CDI86365.1 - 1.7 6.3 10.1 1.6 6.3 7.0 1.0 1 0 0 1 1 1 0 Ycf1 EIIBC-GUT_N PF03612.9 CDI86365.1 - 1.9 8.0 7.0 1.9 8.0 4.9 1.1 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Pex14_N PF04695.8 CDI86365.1 - 2.3 8.2 16.2 2.5 8.1 11.2 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Hid1 PF12722.2 CDI86365.1 - 2.3 5.7 11.2 2.2 5.8 7.7 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF3043 PF11241.3 CDI86365.1 - 2.5 7.6 5.4 2.8 7.5 3.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) Glyco_transf_15 PF01793.11 CDI86365.1 - 2.8 6.8 8.9 2.8 6.8 6.2 1.1 1 0 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase Endonuc_Holl PF10107.4 CDI86365.1 - 3 7.5 9.6 3.4 7.3 6.6 1.1 1 0 0 1 1 1 0 Endonuclease related to archaeal Holliday junction resolvase Serinc PF03348.10 CDI86365.1 - 3.2 6.3 11.4 3.6 6.1 7.9 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) DUF3682 PF12446.3 CDI86365.1 - 3.3 7.9 26.4 4.2 7.6 18.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) Peptidase_S49_N PF08496.5 CDI86365.1 - 3.7 7.3 9.9 4.2 7.1 6.9 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Peroxin-13_N PF04088.8 CDI86365.1 - 3.8 7.4 5.6 5.3 6.9 3.9 1.4 1 0 0 1 1 1 0 Peroxin 13, N-terminal region DUF2347 PF09804.4 CDI86365.1 - 3.9 6.6 8.9 4.3 6.5 6.1 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2347) Pal1 PF08316.6 CDI86365.1 - 4 7.8 6.5 4.6 7.6 4.5 1.1 1 0 0 1 1 1 0 Pal1 cell morphology protein Baculo_PP31 PF05311.6 CDI86365.1 - 4.2 6.5 9.4 4.3 6.5 6.5 1.0 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) CPSF100_C PF13299.1 CDI86365.1 - 4.2 7.5 8.5 4.3 7.4 5.9 1.1 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal DDHD PF02862.12 CDI86365.1 - 4.7 6.9 11.6 5.4 6.7 8.1 1.0 1 0 0 1 1 1 0 DDHD domain DUF2149 PF09919.4 CDI86365.1 - 4.8 7.3 5.7 5.2 7.2 4.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2149) Mem_trans PF03547.13 CDI86365.1 - 5.1 5.2 5.2 5.4 5.2 3.6 1.0 1 0 0 1 1 1 0 Membrane transport protein Spc7_N PF15402.1 CDI86365.1 - 5.3 4.9 15.2 6.3 4.6 10.6 1.0 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 Sec62 PF03839.11 CDI86365.1 - 6.2 6.1 6.8 6.3 6.1 4.7 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 Presenilin PF01080.12 CDI86365.1 - 6.3 5.5 6.6 6.7 5.4 4.6 1.0 1 0 0 1 1 1 0 Presenilin DUF2946 PF11162.3 CDI86365.1 - 6.5 6.9 9.5 7.9 6.7 6.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2946) HGTP_anticodon2 PF12745.2 CDI86365.1 - 6.6 5.7 10.5 7 5.7 7.3 1.1 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs OATP PF03137.15 CDI86365.1 - 6.8 4.6 8.4 6.8 4.6 5.8 1.0 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family CRF1 PF10380.4 CDI86365.1 - 6.9 7.0 8.5 8.2 6.7 5.9 1.1 1 0 0 1 1 1 0 Transcription factor CRF1 Pex16 PF08610.5 CDI86365.1 - 7 5.5 9.0 8.7 5.2 6.2 1.3 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) SHR3_chaperone PF08229.6 CDI86365.1 - 7.6 5.4 11.9 10 5.0 8.3 1.4 1 0 0 1 1 1 0 ER membrane protein SH3 Suf PF05843.9 CDI86365.1 - 9.3 5.8 13.4 11 5.6 9.3 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Host_attach PF10116.4 CDI86365.1 - 9.5 6.4 13.8 12 6.0 9.6 1.0 1 0 0 1 1 1 0 Protein required for attachment to host cells CALCOCO1 PF07888.6 CDI86366.1 - 0.0033 15.7 5.7 0.0033 15.7 3.9 1.7 2 0 0 2 2 2 1 Calcium binding and coiled-coil domain (CALCOCO1) like DivIC PF04977.10 CDI86366.1 - 0.11 12.0 8.5 0.44 10.0 1.1 3.2 2 1 1 3 3 3 0 Septum formation initiator Reo_sigmaC PF04582.7 CDI86366.1 - 0.11 11.6 0.7 0.15 11.1 0.5 1.2 1 0 0 1 1 1 0 Reovirus sigma C capsid protein CDC27 PF09507.5 CDI86366.1 - 0.14 11.3 16.3 0.22 10.7 11.3 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 TEX13 PF15186.1 CDI86366.1 - 0.2 11.2 4.3 0.15 11.6 1.8 1.6 1 1 0 1 1 1 0 Testis-expressed sequence 13 protein family GAS PF13851.1 CDI86366.1 - 0.3 10.2 7.3 0.58 9.3 5.1 1.5 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding FlxA PF14282.1 CDI86366.1 - 0.91 9.4 5.6 0.46 10.4 1.5 2.3 1 1 0 1 1 1 0 FlxA-like protein NPV_P10 PF05531.7 CDI86366.1 - 1.2 9.4 3.7 3.1 8.1 0.7 2.1 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein NYD-SP28_assoc PF14775.1 CDI86366.1 - 7.9 6.2 7.9 10 5.8 0.1 3.2 3 0 0 3 3 3 0 Sperm tail C-terminal domain HALZ PF02183.13 CDI86366.1 - 8.4 6.2 12.0 5.6 6.7 0.2 3.9 3 1 1 4 4 4 0 Homeobox associated leucine zipper NUC173 PF08161.7 CDI86367.1 - 4.1e-14 52.3 2.0 2.2e-13 50.0 0.0 3.1 3 0 0 3 3 3 1 NUC173 domain DUF755 PF05501.6 CDI86367.1 - 0.0042 17.1 5.8 0.0042 17.1 4.0 9.3 8 2 1 9 9 9 1 Domain of unknown function (DUF755) SR-25 PF10500.4 CDI86368.1 - 0.00072 19.0 30.1 0.00092 18.7 20.9 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein CDC45 PF02724.9 CDI86368.1 - 0.19 9.7 31.0 0.22 9.5 21.5 1.0 1 0 0 1 1 1 0 CDC45-like protein SprA-related PF12118.3 CDI86368.1 - 0.75 9.0 57.6 1.1 8.5 39.9 1.2 1 0 0 1 1 1 0 SprA-related family NPR3 PF03666.8 CDI86368.1 - 0.84 8.0 28.6 0.99 7.8 19.8 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 NAM-associated PF14303.1 CDI86368.1 - 0.91 9.8 34.2 1.1 9.4 23.7 1.1 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain eIF-3c_N PF05470.7 CDI86368.1 - 0.92 7.5 18.9 1.1 7.2 13.1 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus FLO_LFY PF01698.11 CDI86368.1 - 1.3 7.8 27.7 1.5 7.6 19.2 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein Utp14 PF04615.8 CDI86368.1 - 1.4 6.9 34.7 1.6 6.7 24.0 1.0 1 0 0 1 1 1 0 Utp14 protein Macoilin PF09726.4 CDI86368.1 - 1.6 6.9 28.0 1.9 6.6 19.4 1.1 1 0 0 1 1 1 0 Transmembrane protein Hid1 PF12722.2 CDI86368.1 - 2.3 5.7 36.9 2.6 5.6 25.6 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF3843 PF12954.2 CDI86368.1 - 3.6 6.5 14.6 3.9 6.4 10.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3843) DUF1675 PF07897.6 CDI86368.1 - 4.1 7.1 29.3 4.7 6.9 20.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) Dicty_REP PF05086.7 CDI86368.1 - 4.7 4.8 29.6 5 4.7 20.5 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein AUX_IAA PF02309.11 CDI86368.1 - 4.8 6.8 26.9 6.9 6.3 18.6 1.2 1 0 0 1 1 1 0 AUX/IAA family SAGA-Tad1 PF12767.2 CDI86368.1 - 5.9 6.4 37.0 7.4 6.1 25.6 1.0 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit DUF3337 PF11816.3 CDI86368.1 - 7 5.9 22.1 7.7 5.7 15.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3337) DUF572 PF04502.8 CDI86368.1 - 8 5.5 31.6 9.6 5.3 21.9 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF4655 PF15548.1 CDI86368.1 - 9.2 5.0 30.3 11 4.8 21.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4655) Macoilin PF09726.4 CDI86369.1 - 0.091 11.0 1.8 0.14 10.3 1.3 1.3 1 0 0 1 1 1 0 Transmembrane protein SIP1 PF04938.7 CDI86369.1 - 0.11 11.8 0.0 0.26 10.6 0.0 1.6 2 0 0 2 2 2 0 Survival motor neuron (SMN) interacting protein 1 (SIP1) Sigma70_ner PF04546.8 CDI86369.1 - 0.24 10.9 4.6 0.46 10.0 3.2 1.5 1 0 0 1 1 1 0 Sigma-70, non-essential region POX PF07526.6 CDI86369.1 - 0.31 11.2 11.8 13 5.9 4.2 3.1 2 1 0 2 2 2 0 Associated with HOX RNA_pol_3_Rpc31 PF11705.3 CDI86369.1 - 0.5 10.2 6.7 0.78 9.6 4.7 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 CENP-B_dimeris PF09026.5 CDI86369.1 - 5.6 7.2 11.4 10 6.3 7.9 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain U1snRNP70_N PF12220.3 CDI86370.1 - 0.028 14.7 2.8 0.028 14.7 1.9 3.3 2 1 1 3 3 3 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal TCTP PF00838.12 CDI86370.1 - 0.21 11.5 2.9 0.36 10.8 2.0 1.5 1 0 0 1 1 1 0 Translationally controlled tumour protein Daxx PF03344.10 CDI86370.1 - 7.8 4.8 40.1 9.2 4.6 27.8 1.0 1 0 0 1 1 1 0 Daxx Family DDRGK PF09756.4 CDI86370.1 - 9.7 5.5 45.4 0.67 9.3 17.9 2.2 2 0 0 2 2 2 0 DDRGK domain Spore_coat_CotO PF14153.1 CDI86371.1 - 0.0007 19.0 15.6 0.00071 19.0 10.8 1.1 1 0 0 1 1 1 1 Spore coat protein CotO Sec62 PF03839.11 CDI86371.1 - 0.032 13.6 8.7 0.041 13.2 6.0 1.0 1 0 0 1 1 1 0 Translocation protein Sec62 DUF4448 PF14610.1 CDI86371.1 - 0.053 13.0 1.9 0.077 12.4 1.3 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF4448) RR_TM4-6 PF06459.7 CDI86371.1 - 0.055 13.3 8.6 0.071 13.0 6.0 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Toxin_R_bind_C PF07951.7 CDI86371.1 - 0.074 12.7 7.7 0.099 12.3 5.4 1.1 1 0 0 1 1 1 0 Clostridium neurotoxin, C-terminal receptor binding Band_3_cyto PF07565.8 CDI86371.1 - 0.086 12.3 10.3 0.089 12.2 7.1 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Tweety PF04906.8 CDI86371.1 - 0.093 11.1 10.5 0.11 10.8 7.3 1.0 1 0 0 1 1 1 0 Tweety LMBR1 PF04791.11 CDI86371.1 - 0.13 10.8 8.6 0.16 10.5 5.9 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein Presenilin PF01080.12 CDI86371.1 - 0.14 10.9 4.8 0.17 10.6 3.3 1.2 1 0 0 1 1 1 0 Presenilin Glyco_hydro_9 PF00759.14 CDI86371.1 - 0.66 8.8 9.3 0.79 8.5 6.5 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 9 DHHW PF14286.1 CDI86371.1 - 0.73 9.0 9.7 0.79 8.9 6.8 1.0 1 0 0 1 1 1 0 DHHW protein UDPGT PF00201.13 CDI86371.1 - 0.78 8.2 6.2 0.82 8.1 4.3 1.0 1 0 0 1 1 1 0 UDP-glucoronosyl and UDP-glucosyl transferase V_ATPase_I PF01496.14 CDI86371.1 - 1 7.1 9.3 1.1 6.9 6.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CemA PF03040.9 CDI86371.1 - 1.2 8.6 12.6 1.4 8.4 8.8 1.1 1 0 0 1 1 1 0 CemA family AUX_IAA PF02309.11 CDI86371.1 - 1.4 8.6 9.4 1.7 8.3 6.5 1.1 1 0 0 1 1 1 0 AUX/IAA family Hira PF07569.6 CDI86371.1 - 1.4 8.0 10.5 1.9 7.6 7.3 1.2 1 0 0 1 1 1 0 TUP1-like enhancer of split YjgP_YjgQ PF03739.9 CDI86371.1 - 1.6 7.4 6.1 2.1 7.0 4.2 1.1 1 0 0 1 1 1 0 Predicted permease YjgP/YjgQ family HlyD_2 PF12700.2 CDI86371.1 - 1.6 7.7 15.6 1.8 7.6 10.8 1.1 1 0 0 1 1 1 0 HlyD family secretion protein DUF2361 PF10153.4 CDI86371.1 - 2.5 8.3 14.9 3.5 7.8 10.3 1.2 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2361) DDHD PF02862.12 CDI86371.1 - 2.7 7.7 11.0 3.2 7.4 7.6 1.1 1 0 0 1 1 1 0 DDHD domain SID-1_RNA_chan PF13965.1 CDI86371.1 - 2.7 6.0 8.4 2.8 6.0 5.9 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Ycf1 PF05758.7 CDI86371.1 - 3.4 5.2 16.2 3.8 5.1 11.2 1.0 1 0 0 1 1 1 0 Ycf1 FAM60A PF15396.1 CDI86371.1 - 4.8 6.8 11.9 5.9 6.5 8.2 1.1 1 0 0 1 1 1 0 Protein Family FAM60A DUF4045 PF13254.1 CDI86371.1 - 5.2 6.2 12.4 6.2 5.9 8.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) PRP1_N PF06424.7 CDI86371.1 - 6.7 7.0 15.0 8.9 6.6 10.4 1.1 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal Herpes_UL87 PF03043.9 CDI86371.1 - 7.4 4.8 10.1 7.6 4.7 7.0 1.0 1 0 0 1 1 1 0 Herpesvirus UL87 family Allexi_40kDa PF05549.6 CDI86371.1 - 7.9 5.6 9.0 9.8 5.3 6.2 1.1 1 0 0 1 1 1 0 Allexivirus 40kDa protein Asp-B-Hydro_N PF05279.6 CDI86371.1 - 8 6.2 16.8 10 5.8 11.6 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region PBP1_TM PF14812.1 CDI86375.1 - 7.6 6.9 26.2 17 5.8 1.2 3.1 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal TPR_19 PF14559.1 CDI86376.1 - 1.1e-05 25.6 0.7 1.8e-05 25.0 0.5 1.3 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_16 PF13432.1 CDI86376.1 - 1.3e-05 25.7 1.1 1.9e-05 25.2 0.2 1.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.12 CDI86376.1 - 2.9e-05 23.6 0.5 0.028 14.3 0.0 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.1 CDI86376.1 - 0.00019 21.0 0.3 0.00033 20.2 0.2 1.5 1 0 0 1 1 1 1 TPR repeat TPR_14 PF13428.1 CDI86376.1 - 0.0019 18.6 2.2 0.12 13.1 0.2 2.7 1 1 2 3 3 3 2 Tetratricopeptide repeat BTAD PF03704.12 CDI86376.1 - 0.0095 16.2 1.4 0.011 15.9 1.0 1.2 1 0 0 1 1 1 1 Bacterial transcriptional activator domain TPR_1 PF00515.23 CDI86376.1 - 0.011 15.2 0.1 0.18 11.4 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat Apc3 PF12895.2 CDI86376.1 - 0.039 14.0 0.1 0.08 13.0 0.1 1.6 1 1 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 IncA PF04156.9 CDI86379.1 - 2.3e-05 24.0 11.7 2.3e-05 24.0 8.1 1.8 2 0 0 2 2 1 1 IncA protein FimP PF09766.4 CDI86379.1 - 8e-05 21.8 7.4 9e-05 21.6 5.1 1.1 1 0 0 1 1 1 1 Fms-interacting protein DUF2232 PF09991.4 CDI86379.1 - 0.00014 20.9 3.1 0.00018 20.6 2.1 1.2 1 0 0 1 1 1 1 Predicted membrane protein (DUF2232) Suf PF05843.9 CDI86379.1 - 0.00038 20.2 5.3 0.00038 20.2 3.7 1.1 1 0 0 1 1 1 1 Suppressor of forked protein (Suf) Gag_spuma PF03276.9 CDI86379.1 - 0.0016 16.8 8.3 0.0016 16.8 5.8 1.2 1 0 0 1 1 1 1 Spumavirus gag protein DUF4557 PF15101.1 CDI86379.1 - 0.0024 17.7 8.7 0.0024 17.7 6.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4557) OATP PF03137.15 CDI86379.1 - 0.0032 15.5 2.0 0.0041 15.2 1.4 1.1 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family DUF912 PF06024.7 CDI86379.1 - 0.0036 17.3 0.8 0.0063 16.5 0.6 1.5 1 0 0 1 1 1 1 Nucleopolyhedrovirus protein of unknown function (DUF912) Spt20 PF12090.3 CDI86379.1 - 0.0047 16.3 3.0 0.0062 15.9 2.1 1.4 1 0 0 1 1 1 1 Spt20 family Peroxin-13_N PF04088.8 CDI86379.1 - 0.0078 16.1 0.4 0.012 15.5 0.3 1.3 1 0 0 1 1 1 1 Peroxin 13, N-terminal region Serinc PF03348.10 CDI86379.1 - 0.009 14.7 5.3 0.0092 14.7 3.6 1.1 1 0 0 1 1 1 1 Serine incorporator (Serinc) PAT1 PF09770.4 CDI86379.1 - 0.01 14.1 22.4 0.01 14.0 15.5 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 zf-DHHC PF01529.15 CDI86379.1 - 0.015 14.7 0.5 0.017 14.5 0.3 1.2 1 0 0 1 1 1 0 DHHC palmitoyltransferase FAM176 PF14851.1 CDI86379.1 - 0.019 14.6 0.4 0.024 14.3 0.3 1.3 1 0 0 1 1 1 0 FAM176 family Ctr PF04145.10 CDI86379.1 - 0.021 14.8 3.5 0.034 14.1 2.4 1.4 1 0 0 1 1 1 0 Ctr copper transporter family RR_TM4-6 PF06459.7 CDI86379.1 - 0.022 14.6 3.2 0.024 14.5 2.2 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 FA_desaturase PF00487.19 CDI86379.1 - 0.023 14.1 0.9 0.03 13.7 0.7 1.2 1 0 0 1 1 1 0 Fatty acid desaturase Glt_symporter PF03616.9 CDI86379.1 - 0.024 13.1 0.7 0.034 12.6 0.5 1.2 1 0 0 1 1 1 0 Sodium/glutamate symporter DUF2370 PF10176.4 CDI86379.1 - 0.027 13.8 1.0 0.035 13.4 0.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) MOR2-PAG1_N PF14222.1 CDI86379.1 - 0.028 13.1 2.0 0.035 12.7 1.4 1.1 1 0 0 1 1 1 0 Cell morphogenesis N-terminal MDFI PF15316.1 CDI86379.1 - 0.043 13.7 7.5 0.054 13.4 5.1 1.2 1 1 0 1 1 1 0 MyoD family inhibitor DUF913 PF06025.7 CDI86379.1 - 0.048 12.4 1.1 0.056 12.1 0.8 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DUF1211 PF06736.6 CDI86379.1 - 0.052 13.6 0.0 0.14 12.3 0.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1211) DUF688 PF05097.7 CDI86379.1 - 0.065 12.1 5.7 0.073 12.0 4.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF688) Spc7_N PF15402.1 CDI86379.1 - 0.068 11.1 5.8 0.078 10.9 4.0 1.1 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 DDHD PF02862.12 CDI86379.1 - 0.076 12.7 3.2 0.08 12.7 2.2 1.1 1 0 0 1 1 1 0 DDHD domain FHIPEP PF00771.15 CDI86379.1 - 0.093 11.0 13.0 0.11 10.8 9.0 1.0 1 0 0 1 1 1 0 FHIPEP family Spore_coat_CotO PF14153.1 CDI86379.1 - 0.12 11.7 12.1 0.16 11.3 8.4 1.2 1 0 0 1 1 1 0 Spore coat protein CotO SID-1_RNA_chan PF13965.1 CDI86379.1 - 0.14 10.2 0.8 0.14 10.2 0.5 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DUF3357 PF11837.3 CDI86379.1 - 0.16 11.8 3.5 1.1 9.1 2.0 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF3357) Baculo_PP31 PF05311.6 CDI86379.1 - 0.16 11.2 4.6 0.18 11.0 3.2 1.2 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) DUF2215 PF10225.4 CDI86379.1 - 0.17 11.2 2.4 0.22 10.9 1.6 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) Med15 PF09606.5 CDI86379.1 - 0.18 9.9 38.6 0.21 9.7 26.7 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Agouti PF05039.7 CDI86379.1 - 0.27 11.6 5.8 0.48 10.7 4.0 1.4 1 0 0 1 1 1 0 Agouti protein FLO_LFY PF01698.11 CDI86379.1 - 0.3 9.8 8.3 0.34 9.7 5.7 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein Topoisom_I PF01028.15 CDI86379.1 - 0.3 10.1 8.8 0.34 9.9 6.1 1.2 1 0 0 1 1 1 0 Eukaryotic DNA topoisomerase I, catalytic core CD20 PF04103.10 CDI86379.1 - 0.32 10.9 7.8 1.1 9.1 5.4 2.0 1 1 0 1 1 1 0 CD20-like family TFIIA PF03153.8 CDI86379.1 - 0.46 10.3 23.5 0.6 9.9 16.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CPSF100_C PF13299.1 CDI86379.1 - 0.51 10.5 4.8 0.74 9.9 3.3 1.3 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal DUF3537 PF12056.3 CDI86379.1 - 0.71 8.5 5.6 0.72 8.4 3.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3537) DUF1980 PF09323.5 CDI86379.1 - 0.79 9.4 4.6 1.1 9.0 3.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) eIF-3_zeta PF05091.7 CDI86379.1 - 0.88 8.1 10.4 1 7.8 7.2 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Med13_N PF11597.3 CDI86379.1 - 1.2 7.7 9.6 1.5 7.3 6.6 1.2 1 0 0 1 1 1 0 Mediator complex subunit 13 N-terminal Presenilin PF01080.12 CDI86379.1 - 1.8 7.3 5.5 2 7.1 3.8 1.2 1 0 0 1 1 1 0 Presenilin Herpes_UL87 PF03043.9 CDI86379.1 - 2.4 6.4 6.8 2.7 6.2 4.7 1.0 1 0 0 1 1 1 0 Herpesvirus UL87 family Band_3_cyto PF07565.8 CDI86379.1 - 2.4 7.6 8.6 3.2 7.1 6.0 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain DUF4131 PF13567.1 CDI86379.1 - 3.2 7.1 9.0 0.57 9.5 2.1 2.3 2 1 1 3 3 2 0 Domain of unknown function (DUF4131) G-alpha PF00503.15 CDI86379.1 - 3.7 6.1 8.6 4.8 5.7 5.9 1.1 1 0 0 1 1 1 0 G-protein alpha subunit HD-ZIP_N PF04618.7 CDI86379.1 - 4.3 7.9 5.8 6.7 7.2 4.0 1.3 1 0 0 1 1 1 0 HD-ZIP protein N terminus UPF0560 PF10577.4 CDI86379.1 - 4.3 5.4 15.4 5.1 5.2 10.7 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 DUF2048 PF09752.4 CDI86379.1 - 4.4 6.0 9.7 2.1 7.1 5.6 1.2 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2048) PBP_sp32 PF07222.7 CDI86379.1 - 4.7 6.3 18.4 6.8 5.7 12.8 1.3 1 0 0 1 1 1 0 Proacrosin binding protein sp32 DUF3270 PF11674.3 CDI86379.1 - 5.8 7.0 9.5 15 5.6 6.6 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3270) AIF_C PF14721.1 CDI86379.1 - 7.8 6.7 13.7 4.5 7.5 8.2 1.6 1 1 1 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term AAA_23 PF13476.1 CDI86379.1 - 8.3 6.6 9.2 10 6.3 6.4 1.1 1 0 0 1 1 1 0 AAA domain SR-25 PF10500.4 CDI86380.1 - 2 7.8 48.1 0.55 9.6 18.4 2.2 1 1 1 2 2 2 0 Nuclear RNA-splicing-associated protein DUF3801 PF12687.2 CDI86380.1 - 9.9 5.6 33.3 12 5.3 23.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3801) SAGA-Tad1 PF12767.2 CDI86381.1 - 2 8.0 59.3 0.76 9.3 1.3 2.5 2 0 0 2 2 2 0 Transcriptional regulator of RNA polII, SAGA, subunit FAM60A PF15396.1 CDI86381.1 - 7.2 6.2 46.3 1.7 8.3 1.0 2.6 2 0 0 2 2 2 0 Protein Family FAM60A Herpes_BLLF1 PF05109.8 CDI86381.1 - 8.3 4.2 63.2 11 3.8 43.8 1.1 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) DUF940 PF06082.6 CDI86382.1 - 0.38 9.2 13.0 0.42 9.1 9.0 1.0 1 0 0 1 1 1 0 Bacterial putative lipoprotein (DUF940) RR_TM4-6 PF06459.7 CDI86382.1 - 0.74 9.6 12.6 0.85 9.4 8.7 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Serinc PF03348.10 CDI86382.1 - 1.6 7.3 9.1 2.3 6.8 6.3 1.3 1 0 0 1 1 1 0 Serine incorporator (Serinc) Neur_chan_memb PF02932.11 CDI86382.1 - 1.7 8.4 10.3 2.1 8.1 7.1 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region SID-1_RNA_chan PF13965.1 CDI86382.1 - 2.7 6.0 5.6 2.8 5.9 3.9 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DDHD PF02862.12 CDI86382.1 - 2.8 7.6 10.7 3.3 7.4 7.4 1.2 1 0 0 1 1 1 0 DDHD domain FAM60A PF15396.1 CDI86382.1 - 6.3 6.4 10.7 7.1 6.3 7.4 1.2 1 0 0 1 1 1 0 Protein Family FAM60A Gag_spuma PF03276.9 CDI86382.1 - 8 4.6 26.0 9.1 4.4 18.0 1.1 1 0 0 1 1 1 0 Spumavirus gag protein UPF0093 PF03653.8 CDI86384.1 - 0.94 9.4 3.7 1.7 8.5 0.0 3.2 4 0 0 4 4 4 0 Uncharacterised protein family (UPF0093) Tim54 PF11711.3 CDI86386.1 - 0.0019 16.8 9.3 0.0021 16.7 6.4 1.0 1 0 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 DUF3535 PF12054.3 CDI86386.1 - 0.0024 16.5 11.9 0.0028 16.3 8.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3535) Pal1 PF08316.6 CDI86386.1 - 0.014 15.8 7.0 0.015 15.7 4.8 1.1 1 0 0 1 1 1 0 Pal1 cell morphology protein DUF2126 PF09899.4 CDI86386.1 - 0.022 12.8 14.6 0.025 12.6 10.1 1.0 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) Med19 PF10278.4 CDI86386.1 - 0.034 13.8 8.2 0.036 13.7 5.7 1.1 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 RR_TM4-6 PF06459.7 CDI86386.1 - 0.069 13.0 18.3 0.074 12.9 12.7 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 AAA_23 PF13476.1 CDI86386.1 - 0.086 13.1 27.2 0.09 13.0 18.8 1.1 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.1 CDI86386.1 - 0.12 11.9 15.7 0.13 11.8 10.9 1.1 1 0 0 1 1 1 0 AAA domain AUX_IAA PF02309.11 CDI86386.1 - 0.18 11.4 15.1 0.22 11.2 10.5 1.1 1 0 0 1 1 1 0 AUX/IAA family DUF1266 PF06889.6 CDI86386.1 - 0.22 11.2 9.6 0.27 11.0 6.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1266) Zip PF02535.17 CDI86386.1 - 0.23 10.4 4.9 0.24 10.3 3.4 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter OATP PF03137.15 CDI86386.1 - 0.36 8.8 12.0 0.47 8.4 8.3 1.3 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family DUF1675 PF07897.6 CDI86386.1 - 0.38 10.5 10.8 0.35 10.7 7.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) TFIIA PF03153.8 CDI86386.1 - 0.48 10.2 39.7 0.5 10.2 27.5 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit HemX PF04375.9 CDI86386.1 - 0.71 8.3 36.8 0.81 8.2 25.5 1.0 1 0 0 1 1 1 0 HemX Ycf1 PF05758.7 CDI86386.1 - 0.98 7.0 20.9 0.99 7.0 14.5 1.0 1 0 0 1 1 1 0 Ycf1 DUF4512 PF14975.1 CDI86386.1 - 1.1 10.1 12.1 1.4 9.8 8.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4512) RIC3 PF15361.1 CDI86386.1 - 1.2 9.3 20.1 1.5 9.0 13.9 1.1 1 0 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 DUF1510 PF07423.6 CDI86386.1 - 1.3 8.3 25.9 1.6 8.0 18.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Dynamin_N PF00350.18 CDI86386.1 - 1.5 8.5 10.3 2.1 8.1 7.1 1.3 1 0 0 1 1 1 0 Dynamin family PAT1 PF09770.4 CDI86386.1 - 1.9 6.6 56.4 1.9 6.5 39.1 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Pap_E4 PF02711.9 CDI86386.1 - 2.4 9.0 19.3 3.4 8.5 13.4 1.3 1 0 0 1 1 1 0 E4 protein Folate_carrier PF01770.13 CDI86386.1 - 2.5 6.5 14.2 2.9 6.2 9.9 1.0 1 0 0 1 1 1 0 Reduced folate carrier Herpes_DNAp_acc PF04929.7 CDI86386.1 - 2.6 6.8 17.8 2.9 6.7 12.3 1.0 1 0 0 1 1 1 0 Herpes DNA replication accessory factor FAM60A PF15396.1 CDI86386.1 - 4.4 6.9 18.3 4.8 6.8 12.7 1.1 1 0 0 1 1 1 0 Protein Family FAM60A Raftlin PF15250.1 CDI86386.1 - 4.5 5.6 21.1 4.8 5.5 14.6 1.0 1 0 0 1 1 1 0 Raftlin MRI PF15325.1 CDI86386.1 - 5.3 8.0 11.1 6.9 7.7 7.7 1.1 1 0 0 1 1 1 0 Modulator of retrovirus infection Gag_spuma PF03276.9 CDI86386.1 - 5.3 5.2 42.9 6.3 5.0 29.8 1.0 1 0 0 1 1 1 0 Spumavirus gag protein Plasmodium_Vir PF05795.6 CDI86386.1 - 6 5.9 9.8 6.1 5.9 6.8 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein AMP-binding PF00501.23 CDI86386.1 - 6.4 5.0 5.7 7.2 4.8 4.0 1.0 1 0 0 1 1 1 0 AMP-binding enzyme DUF4446 PF14584.1 CDI86386.1 - 8.1 6.2 13.4 11 5.8 9.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) DDHD PF02862.12 CDI86386.1 - 8.7 6.0 23.2 11 5.7 16.1 1.1 1 0 0 1 1 1 0 DDHD domain SprA-related PF12118.3 CDI86388.1 - 0.0021 17.4 21.2 0.0021 17.4 14.7 6.3 4 2 1 5 5 5 2 SprA-related family TraT PF05818.7 CDI86388.1 - 0.0047 16.3 4.7 0.0047 16.3 3.3 6.2 5 1 1 6 6 6 1 Enterobacterial TraT complement resistance protein Med15 PF09606.5 CDI86389.1 - 4.6e-05 21.8 93.3 5.2e-05 21.6 64.7 1.0 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal GPCR_chapero_1 PF11904.3 CDI86389.1 - 3.5 6.6 25.3 4.6 6.2 17.6 1.3 1 0 0 1 1 1 0 GPCR-chaperone Asp-B-Hydro_N PF05279.6 CDI86389.1 - 7.3 6.3 30.4 8.2 6.1 21.1 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region PCEMA1 PF07418.6 CDI86389.1 - 7.8 5.7 17.4 10 5.4 12.1 1.3 1 0 0 1 1 1 0 Acidic phosphoprotein precursor PCEMA1 DUF429 PF04250.8 CDI86390.1 - 0.21 10.8 7.8 1.1 8.4 1.3 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF429) Med15 PF09606.5 CDI86390.1 - 1.3 7.1 73.9 1.7 6.7 51.2 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal MRP-S31 PF15433.1 CDI86390.1 - 1.5 8.1 26.6 1.7 8.0 12.4 2.2 2 0 0 2 2 2 0 Mitochondrial 28S ribosomal protein S31 CAF-1_p150 PF11600.3 CDI86390.1 - 2.9 7.2 28.2 0.73 9.1 13.3 2.2 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DOR PF14839.1 CDI86390.1 - 3.7 7.2 33.1 0.24 11.1 3.1 2.3 2 0 0 2 2 2 0 DOR family AAA_23 PF13476.1 CDI86390.1 - 3.8 7.7 21.1 1.8 8.8 3.9 2.2 2 0 0 2 2 2 0 AAA domain Utp14 PF04615.8 CDI86390.1 - 6.3 4.8 27.4 8.1 4.4 19.0 1.1 1 0 0 1 1 1 0 Utp14 protein NT-C2 PF10358.4 CDI86392.1 - 3.1e-06 26.7 0.0 0.057 12.9 0.0 2.5 2 0 0 2 2 2 2 N-terminal C2 in EEIG1 and EHBP1 proteins Spt20 PF12090.3 CDI86393.1 - 0.00017 21.0 9.9 0.05 12.9 4.7 2.5 2 0 0 2 2 2 2 Spt20 family Suf PF05843.9 CDI86393.1 - 0.00077 19.2 13.3 0.0021 17.8 4.2 2.2 2 0 0 2 2 2 1 Suppressor of forked protein (Suf) DUF4175 PF13779.1 CDI86393.1 - 0.00083 17.1 37.0 0.0092 13.7 17.3 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF4175) Gti1_Pac2 PF09729.4 CDI86393.1 - 0.0022 17.9 0.8 0.069 13.0 0.6 2.2 2 0 0 2 2 2 1 Gti1/Pac2 family AAA_23 PF13476.1 CDI86393.1 - 0.0042 17.4 13.6 0.034 14.4 4.8 2.2 2 0 0 2 2 2 1 AAA domain Band_3_cyto PF07565.8 CDI86393.1 - 0.0053 16.2 6.5 0.01 15.4 1.6 2.2 2 0 0 2 2 2 1 Band 3 cytoplasmic domain Pex16 PF08610.5 CDI86393.1 - 0.0061 15.6 7.0 0.007 15.4 1.6 2.1 2 0 0 2 2 2 1 Peroxisomal membrane protein (Pex16) Med15 PF09606.5 CDI86393.1 - 0.0075 14.5 55.7 0.025 12.7 26.4 2.1 2 0 0 2 2 2 2 ARC105 or Med15 subunit of Mediator complex non-fungal DUF4647 PF15504.1 CDI86393.1 - 0.008 15.0 10.3 0.011 14.6 2.6 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4647) Apc15p PF05841.6 CDI86393.1 - 0.014 16.1 7.0 0.014 16.1 4.8 2.7 3 0 0 3 3 2 0 Apc15p protein DDHD PF02862.12 CDI86393.1 - 0.02 14.7 5.5 0.1 12.3 2.3 2.2 2 0 0 2 2 2 0 DDHD domain DUF2201_N PF13203.1 CDI86393.1 - 0.02 14.0 17.7 0.037 13.1 7.4 2.2 2 0 0 2 2 2 0 Putative metallopeptidase domain eIF-3_zeta PF05091.7 CDI86393.1 - 0.021 13.4 12.2 0.0059 15.2 3.2 2.1 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Mem_trans PF03547.13 CDI86393.1 - 0.023 13.0 0.5 0.037 12.3 0.3 1.3 1 0 0 1 1 1 0 Membrane transport protein SAGA-Tad1 PF12767.2 CDI86393.1 - 0.032 13.8 12.5 0.017 14.8 3.9 2.3 2 0 0 2 2 2 0 Transcriptional regulator of RNA polII, SAGA, subunit DUF3371 PF11851.3 CDI86393.1 - 0.034 14.8 17.9 0.062 13.9 5.6 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3371) Pex14_N PF04695.8 CDI86393.1 - 0.039 13.9 20.4 0.077 13.0 8.8 2.6 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Serinc PF03348.10 CDI86393.1 - 0.04 12.6 9.7 0.085 11.5 4.3 2.0 2 0 0 2 2 2 0 Serine incorporator (Serinc) ABC2_membrane_2 PF12679.2 CDI86393.1 - 0.048 12.5 3.3 0.19 10.5 0.7 2.2 2 0 0 2 2 2 0 ABC-2 family transporter protein Peroxin-13_N PF04088.8 CDI86393.1 - 0.053 13.4 7.2 0.24 11.3 1.9 2.3 2 0 0 2 2 2 0 Peroxin 13, N-terminal region RED_N PF07808.8 CDI86393.1 - 0.054 12.7 23.3 0.31 10.2 11.8 2.2 2 0 0 2 2 2 0 RED-like protein N-terminal region SID-1_RNA_chan PF13965.1 CDI86393.1 - 0.055 11.6 2.1 0.092 10.8 1.5 1.3 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Hid1 PF12722.2 CDI86393.1 - 0.058 11.0 6.3 0.018 12.7 1.9 1.8 2 0 0 2 2 2 0 High-temperature-induced dauer-formation protein Herpes_Helicase PF02689.9 CDI86393.1 - 0.073 10.8 4.1 0.11 10.2 2.9 1.3 1 0 0 1 1 1 0 Helicase zf-DHHC PF01529.15 CDI86393.1 - 0.076 12.4 1.8 0.4 10.0 0.4 2.1 2 0 0 2 2 2 0 DHHC palmitoyltransferase SOBP PF15279.1 CDI86393.1 - 0.11 12.9 9.9 0.11 12.8 4.3 2.0 2 0 0 2 2 2 0 Sine oculis-binding protein Ctr PF04145.10 CDI86393.1 - 0.11 12.5 7.6 0.067 13.2 1.2 2.5 2 0 0 2 2 2 0 Ctr copper transporter family FAM176 PF14851.1 CDI86393.1 - 0.11 12.1 5.0 0.2 11.3 1.2 2.2 2 0 0 2 2 2 0 FAM176 family FHIPEP PF00771.15 CDI86393.1 - 0.11 10.7 9.7 0.03 12.6 2.9 2.2 2 0 0 2 2 2 0 FHIPEP family PEX11 PF05648.9 CDI86393.1 - 0.14 11.4 9.7 1.1 8.5 2.7 2.4 2 1 0 2 2 2 0 Peroxisomal biogenesis factor 11 (PEX11) AUX_IAA PF02309.11 CDI86393.1 - 0.21 11.3 6.7 0.33 10.6 2.3 2.1 2 0 0 2 2 2 0 AUX/IAA family FLO_LFY PF01698.11 CDI86393.1 - 0.22 10.3 10.5 0.42 9.4 3.3 2.2 2 0 0 2 2 2 0 Floricaula / Leafy protein CPSF100_C PF13299.1 CDI86393.1 - 0.25 11.5 7.0 0.54 10.4 2.7 2.3 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal GPCR_chapero_1 PF11904.3 CDI86393.1 - 0.3 10.1 8.1 0.22 10.6 3.4 1.9 2 0 0 2 2 2 0 GPCR-chaperone PIH1 PF08190.7 CDI86393.1 - 0.4 10.0 16.9 0.053 12.9 6.0 2.1 2 0 0 2 2 2 0 pre-RNA processing PIH1/Nop17 Peptidase_S49_N PF08496.5 CDI86393.1 - 0.41 10.4 11.6 0.23 11.2 3.1 2.3 2 0 0 2 2 2 0 Peptidase family S49 N-terminal DUF4045 PF13254.1 CDI86393.1 - 0.52 9.5 12.7 0.14 11.3 6.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4045) DUF2098 PF09871.4 CDI86393.1 - 0.63 10.0 4.8 6.6 6.7 3.0 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2098) Afi1 PF07792.7 CDI86393.1 - 0.65 10.0 13.6 0.61 10.0 5.5 2.3 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Macoilin PF09726.4 CDI86393.1 - 0.8 7.9 13.7 0.29 9.3 3.0 2.2 2 0 0 2 2 2 0 Transmembrane protein Spore_coat_CotO PF14153.1 CDI86393.1 - 1 8.7 20.9 0.29 10.5 8.0 2.2 2 0 0 2 2 2 0 Spore coat protein CotO DUF45 PF01863.12 CDI86393.1 - 1 9.0 9.1 1.4 8.6 2.1 2.6 3 0 0 3 3 2 0 Protein of unknown function DUF45 Draxin PF15550.1 CDI86393.1 - 1.3 8.6 12.0 0.36 10.4 2.7 2.1 2 0 0 2 2 2 0 Draxin Hom_end_hint PF05203.11 CDI86393.1 - 1.5 8.5 10.9 1.6 8.4 3.0 2.2 2 0 0 2 2 2 0 Hom_end-associated Hint FAM60A PF15396.1 CDI86393.1 - 1.8 8.2 7.8 2.4 7.8 3.4 2.1 2 0 0 2 2 2 0 Protein Family FAM60A PH_4 PF15404.1 CDI86393.1 - 2.4 7.6 15.5 1.5 8.3 7.3 2.1 2 0 0 2 2 2 0 Pleckstrin homology domain FimP PF09766.4 CDI86393.1 - 2.5 7.0 33.5 0.68 8.9 0.3 2.2 2 0 0 2 2 2 0 Fms-interacting protein Baculo_PP31 PF05311.6 CDI86393.1 - 2.6 7.2 12.3 0.66 9.1 5.0 2.0 2 0 0 2 2 2 0 Baculovirus 33KDa late protein (PP31) Dala_Dala_lig_N PF01820.16 CDI86393.1 - 2.6 8.3 7.6 3.8 7.8 2.9 2.3 2 0 0 2 2 2 0 D-ala D-ala ligase N-terminus Na_trans_assoc PF06512.8 CDI86393.1 - 2.8 7.8 9.2 0.63 9.9 2.0 2.1 2 0 0 2 2 2 0 Sodium ion transport-associated Conotoxin PF02950.12 CDI86393.1 - 3 8.7 10.5 12 6.7 2.9 2.8 2 0 0 2 2 2 0 Conotoxin OATP PF03137.15 CDI86393.1 - 3.5 5.5 11.3 0.9 7.5 4.8 1.8 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family PAT1 PF09770.4 CDI86393.1 - 3.6 5.7 43.2 1.6 6.8 20.5 2.1 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 VID27 PF08553.5 CDI86393.1 - 4.1 5.4 12.3 0.22 9.7 4.9 1.4 2 0 0 2 2 2 0 VID27 cytoplasmic protein Sporozoite_P67 PF05642.6 CDI86393.1 - 4.4 5.0 8.3 3.2 5.5 4.4 1.6 2 0 0 2 2 2 0 Sporozoite P67 surface antigen 60KD_IMP PF02096.15 CDI86393.1 - 4.5 6.8 18.4 11 5.6 0.0 2.2 2 0 0 2 2 2 0 60Kd inner membrane protein Endonuc_Holl PF10107.4 CDI86393.1 - 5.2 6.7 16.9 8 6.1 7.8 2.5 3 0 0 3 3 2 0 Endonuclease related to archaeal Holliday junction resolvase Folate_carrier PF01770.13 CDI86393.1 - 5.3 5.4 8.0 3.7 5.9 3.9 1.8 2 0 0 2 2 2 0 Reduced folate carrier EIIBC-GUT_N PF03612.9 CDI86393.1 - 5.3 6.6 14.4 2.7 7.5 6.3 2.2 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus MRP-S31 PF15433.1 CDI86393.1 - 5.5 6.3 20.5 3.5 6.9 9.1 2.3 2 0 0 2 2 2 0 Mitochondrial 28S ribosomal protein S31 ATAD4 PF15321.1 CDI86393.1 - 5.6 8.0 14.8 35 5.4 7.2 2.5 2 0 0 2 2 2 0 ATPase family AAA domain containing 4 IER PF05760.7 CDI86393.1 - 5.7 6.7 21.2 0.39 10.5 9.1 2.1 2 0 0 2 2 2 0 Immediate early response protein (IER) DUF106 PF01956.11 CDI86393.1 - 6 6.3 11.1 1.6 8.2 4.1 2.1 2 0 0 2 2 2 0 Integral membrane protein DUF106 DUF4496 PF14908.1 CDI86393.1 - 6.4 6.6 13.4 4.5 7.1 4.7 3.0 4 0 0 4 4 2 0 Domain of unknown function (DUF4496) DivIC PF04977.10 CDI86393.1 - 7.2 6.1 36.0 3.3 7.2 13.5 2.7 2 0 0 2 2 2 0 Septum formation initiator Pex14_N PF04695.8 CDI86394.1 - 1.3e-11 44.7 33.5 1.3e-11 44.6 5.5 2.3 1 1 1 2 2 2 2 Peroxisomal membrane anchor protein (Pex14p) conserved region FGE-sulfatase PF03781.11 CDI86394.1 - 0.17 11.2 10.9 0.21 10.9 7.6 1.0 1 0 0 1 1 1 0 Sulfatase-modifying factor enzyme 1 DUF966 PF06136.8 CDI86394.1 - 0.34 10.2 12.9 0.42 9.9 8.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) TCP PF03634.8 CDI86394.1 - 1.1 9.5 21.4 0.33 11.3 7.6 2.1 2 0 0 2 2 2 0 TCP family transcription factor DUF3371 PF11851.3 CDI86394.1 - 1.6 9.4 27.4 0.72 10.5 6.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3371) Parvo_coat PF00740.13 CDI86394.1 - 1.7 7.4 22.5 2.2 7.1 15.6 1.0 1 0 0 1 1 1 0 Parvovirus coat protein VP2 ATAD4 PF15321.1 CDI86394.1 - 2.5 9.1 12.3 0.95 10.5 2.6 2.4 2 0 0 2 2 2 0 ATPase family AAA domain containing 4 AAA-ATPase_like PF09820.4 CDI86394.1 - 5.7 6.0 7.0 1.4 8.0 0.1 2.0 2 0 0 2 2 2 0 Predicted AAA-ATPase MAPEG PF01124.13 CDI86394.1 - 7.6 6.1 8.1 0.9 9.1 2.4 1.7 1 1 1 2 2 2 0 MAPEG family IncA PF04156.9 CDI86394.1 - 8.6 5.8 31.5 0.89 9.1 4.1 2.1 2 0 0 2 2 2 0 IncA protein MRP-S31 PF15433.1 CDI86394.1 - 9.6 5.5 23.4 11 5.2 16.2 1.1 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 EF-hand_7 PF13499.1 CDI86395.1 - 9.8e-06 25.6 0.0 0.0019 18.3 0.0 2.6 1 1 2 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.27 CDI86395.1 - 2.1e-05 23.4 0.1 0.00073 18.6 0.0 3.0 3 0 0 3 3 3 1 EF hand EF-hand_6 PF13405.1 CDI86395.1 - 0.00017 21.1 0.0 0.0014 18.3 0.0 2.5 4 0 0 4 4 4 1 EF-hand domain EF-hand_5 PF13202.1 CDI86395.1 - 0.091 12.1 0.6 0.79 9.1 0.0 2.8 3 0 0 3 3 3 0 EF hand PG_binding_4 PF12229.3 CDI86397.1 - 0.05 13.8 0.8 0.05 13.8 0.6 2.1 1 1 1 2 2 2 0 Putative peptidoglycan binding domain DUF2203 PF09969.4 CDI86397.1 - 0.83 9.8 8.6 0.11 12.7 0.7 2.5 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) Peptidase_S64 PF08192.6 CDI86397.1 - 3.3 5.9 13.6 3.8 5.7 9.4 1.1 1 0 0 1 1 1 0 Peptidase family S64 AAA_23 PF13476.1 CDI86397.1 - 3.5 7.8 9.7 2.5 8.3 5.6 1.5 2 0 0 2 2 2 0 AAA domain DUF3595 PF12166.3 CDI86397.1 - 7.9 5.1 9.0 9.4 4.9 6.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3595) DUF1764 PF08576.5 CDI86397.1 - 9.1 7.1 7.8 2 9.2 1.0 2.5 2 1 1 3 3 3 0 Eukaryotic protein of unknown function (DUF1764) RskA PF10099.4 CDI86400.1 - 0.0022 17.7 5.3 0.0026 17.5 3.7 1.1 1 0 0 1 1 1 1 Anti-sigma-K factor rskA Suf PF05843.9 CDI86400.1 - 0.0066 16.2 8.6 0.0066 16.2 6.0 1.0 1 0 0 1 1 1 1 Suppressor of forked protein (Suf) CDC45 PF02724.9 CDI86400.1 - 0.0075 14.3 1.5 0.0079 14.2 1.1 1.0 1 0 0 1 1 1 1 CDC45-like protein DUF4094 PF13334.1 CDI86400.1 - 0.0091 16.3 2.4 0.012 15.9 1.7 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4094) FimP PF09766.4 CDI86400.1 - 0.016 14.3 12.3 0.016 14.2 8.6 1.0 1 0 0 1 1 1 0 Fms-interacting protein Spt20 PF12090.3 CDI86400.1 - 0.019 14.3 6.7 0.019 14.3 4.6 1.1 1 0 0 1 1 1 0 Spt20 family Helicase_RecD PF05127.9 CDI86400.1 - 0.033 13.8 4.4 0.042 13.4 3.0 1.2 1 0 0 1 1 1 0 Helicase DUF912 PF06024.7 CDI86400.1 - 0.052 13.6 1.1 0.054 13.5 0.8 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) zf-DHHC PF01529.15 CDI86400.1 - 0.061 12.7 1.5 0.057 12.8 1.0 1.1 1 0 0 1 1 1 0 DHHC palmitoyltransferase Glt_symporter PF03616.9 CDI86400.1 - 0.072 11.5 0.8 0.079 11.4 0.6 1.0 1 0 0 1 1 1 0 Sodium/glutamate symporter Cyclin_C PF02984.14 CDI86400.1 - 0.11 12.3 2.4 0.16 11.8 1.7 1.2 1 0 0 1 1 1 0 Cyclin, C-terminal domain AIF_C PF14721.1 CDI86400.1 - 0.13 12.5 2.3 0.13 12.5 1.6 1.2 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term DUF4557 PF15101.1 CDI86400.1 - 0.13 12.0 10.6 0.12 12.1 7.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) Med15 PF09606.5 CDI86400.1 - 0.14 10.3 30.4 0.16 10.1 21.1 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal PAT1 PF09770.4 CDI86400.1 - 0.15 10.2 18.7 0.14 10.3 13.0 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF2453 PF10507.4 CDI86400.1 - 0.23 11.2 1.1 0.3 10.9 0.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2453) OATP PF03137.15 CDI86400.1 - 0.29 9.1 3.3 0.28 9.1 2.3 1.0 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Band_3_cyto PF07565.8 CDI86400.1 - 0.31 10.5 4.8 0.3 10.5 3.3 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain R_equi_Vir PF05526.6 CDI86400.1 - 0.47 10.0 3.9 0.54 9.8 2.7 1.1 1 0 0 1 1 1 0 Rhodococcus equi virulence-associated protein RR_TM4-6 PF06459.7 CDI86400.1 - 0.51 10.1 5.2 0.47 10.2 3.6 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SprA-related PF12118.3 CDI86400.1 - 0.58 9.4 22.1 0.67 9.2 15.3 1.1 1 0 0 1 1 1 0 SprA-related family HemX PF04375.9 CDI86400.1 - 0.6 8.6 15.2 0.72 8.3 10.5 1.0 1 0 0 1 1 1 0 HemX Ctr PF04145.10 CDI86400.1 - 0.61 10.1 4.8 0.94 9.5 3.4 1.4 1 1 0 1 1 1 0 Ctr copper transporter family DUF775 PF05603.7 CDI86400.1 - 0.66 9.4 7.5 0.68 9.4 5.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF775) DUF1071 PF06378.6 CDI86400.1 - 0.71 9.0 8.5 0.83 8.7 5.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1071) DUF4045 PF13254.1 CDI86400.1 - 0.74 9.0 7.4 0.81 8.9 5.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Kei1 PF08552.6 CDI86400.1 - 0.81 9.3 3.6 0.81 9.3 2.5 1.1 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 DUF2232 PF09991.4 CDI86400.1 - 1.2 8.0 2.9 1.3 7.9 2.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) SHR3_chaperone PF08229.6 CDI86400.1 - 1.3 7.9 8.0 1.4 7.8 5.5 1.1 1 0 0 1 1 1 0 ER membrane protein SH3 DUF3043 PF11241.3 CDI86400.1 - 1.5 8.3 4.7 1.6 8.2 3.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) Gag_spuma PF03276.9 CDI86400.1 - 1.5 7.0 18.1 1.6 6.9 12.5 1.1 1 0 0 1 1 1 0 Spumavirus gag protein Serinc PF03348.10 CDI86400.1 - 1.6 7.3 6.4 1.7 7.3 4.4 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) G0-G1_switch_2 PF15103.1 CDI86400.1 - 1.6 9.0 6.2 2 8.7 4.3 1.2 1 0 0 1 1 1 0 G0/G1 switch protein 2 DDHD PF02862.12 CDI86400.1 - 1.8 8.2 7.3 1.9 8.2 5.1 1.1 1 0 0 1 1 1 0 DDHD domain CIAPIN1 PF05093.8 CDI86400.1 - 2.1 8.5 9.0 2.6 8.2 6.1 1.3 1 1 0 1 1 1 0 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis DUF1360 PF07098.6 CDI86400.1 - 3 7.5 6.5 0.33 10.6 1.8 1.4 2 0 0 2 2 1 0 Protein of unknown function (DUF1360) DUF788 PF05620.6 CDI86400.1 - 3.2 7.5 9.1 3.5 7.4 6.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF788) Chorion_3 PF05387.6 CDI86400.1 - 3.6 6.9 14.1 4.2 6.7 9.8 1.0 1 0 0 1 1 1 0 Chorion family 3 Pex16 PF08610.5 CDI86400.1 - 3.8 6.4 7.2 4.1 6.2 5.0 1.1 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) AAA_23 PF13476.1 CDI86400.1 - 4.8 7.4 10.1 5.1 7.3 7.0 1.1 1 0 0 1 1 1 0 AAA domain UPF0560 PF10577.4 CDI86400.1 - 4.8 5.3 13.0 4.9 5.2 9.0 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 DUF4175 PF13779.1 CDI86400.1 - 5 4.6 27.3 5.6 4.5 18.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) DUF4199 PF13858.1 CDI86400.1 - 5.1 6.9 5.8 7.5 6.4 4.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) RAB3GAP2_N PF14655.1 CDI86400.1 - 5.5 5.8 13.9 8.7 5.2 9.6 1.4 1 1 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus DUF4407 PF14362.1 CDI86400.1 - 5.7 5.8 15.5 7.1 5.4 10.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) eIF_4EBP PF05456.6 CDI86400.1 - 7.4 6.2 8.0 10 5.8 5.5 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) SseC PF04888.7 CDI86401.1 - 0.0035 16.7 18.6 0.0035 16.7 12.9 11.7 6 3 4 10 10 10 1 Secretion system effector C (SseC) like family N6_N4_Mtase PF01555.13 CDI86401.1 - 0.019 14.4 0.6 21 4.5 0.0 4.0 3 1 0 3 3 3 0 DNA methylase Spt20 PF12090.3 CDI86402.1 - 0.0013 18.1 4.4 0.0013 18.1 3.0 1.1 1 0 0 1 1 1 1 Spt20 family IncA PF04156.9 CDI86402.1 - 0.0017 17.9 3.9 0.0024 17.4 2.7 1.2 1 0 0 1 1 1 1 IncA protein RAB3GAP2_N PF14655.1 CDI86402.1 - 0.0024 16.9 5.1 0.0027 16.7 3.6 1.1 1 0 0 1 1 1 1 Rab3 GTPase-activating protein regulatory subunit N-terminus Wzz PF02706.10 CDI86402.1 - 0.0074 16.1 4.2 0.012 15.4 2.9 1.3 1 0 0 1 1 1 1 Chain length determinant protein FimP PF09766.4 CDI86402.1 - 0.0075 15.3 9.2 0.008 15.2 6.4 1.1 1 0 0 1 1 1 1 Fms-interacting protein Med15 PF09606.5 CDI86402.1 - 0.0092 14.2 26.1 0.01 14.0 18.1 1.1 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal Suf PF05843.9 CDI86402.1 - 0.0098 15.6 12.1 0.011 15.5 8.4 1.1 1 0 0 1 1 1 1 Suppressor of forked protein (Suf) DUF3801 PF12687.2 CDI86402.1 - 0.013 15.1 3.2 0.014 15.0 2.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3801) FHIPEP PF00771.15 CDI86402.1 - 0.017 13.5 3.5 0.019 13.3 2.4 1.0 1 0 0 1 1 1 0 FHIPEP family Dendrin PF15498.1 CDI86402.1 - 0.02 13.4 9.8 0.022 13.2 6.8 1.0 1 0 0 1 1 1 0 Nephrin and CD2AP-binding protein, Dendrin Bac_luciferase PF00296.15 CDI86402.1 - 0.034 13.2 9.9 0.04 13.0 6.9 1.0 1 0 0 1 1 1 0 Luciferase-like monooxygenase Gag_spuma PF03276.9 CDI86402.1 - 0.04 12.2 12.6 0.04 12.2 8.8 1.2 1 0 0 1 1 1 0 Spumavirus gag protein DUF4259 PF14078.1 CDI86402.1 - 0.098 13.1 4.4 0.14 12.6 3.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4259) Ofd1_CTDD PF10637.4 CDI86402.1 - 0.13 11.3 1.4 0.13 11.3 1.0 1.1 1 0 0 1 1 1 0 Oxoglutarate and iron-dependent oxygenase degradation C-term Baculo_PP31 PF05311.6 CDI86402.1 - 0.25 10.5 6.9 0.27 10.4 4.8 1.1 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) PGA2 PF07543.7 CDI86402.1 - 0.25 11.1 4.7 0.32 10.7 3.3 1.1 1 0 0 1 1 1 0 Protein trafficking PGA2 eIF-3_zeta PF05091.7 CDI86402.1 - 0.34 9.4 6.2 0.33 9.5 4.3 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) XRCC4 PF06632.7 CDI86402.1 - 0.54 9.0 7.2 0.68 8.7 5.0 1.1 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 Serinc PF03348.10 CDI86402.1 - 0.72 8.4 4.9 0.73 8.4 3.4 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) FLO_LFY PF01698.11 CDI86402.1 - 0.85 8.4 6.3 0.97 8.2 4.4 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein MDFI PF15316.1 CDI86402.1 - 1.6 8.7 5.5 1.7 8.6 3.8 1.1 1 0 0 1 1 1 0 MyoD family inhibitor UPF0560 PF10577.4 CDI86402.1 - 2.7 6.1 11.1 2.7 6.1 7.7 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 DUF913 PF06025.7 CDI86402.1 - 3.5 6.2 6.6 4.1 6.0 4.5 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) TFIIA PF03153.8 CDI86402.1 - 3.8 7.2 22.2 4.2 7.1 15.4 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit TCP PF03634.8 CDI86402.1 - 4 7.8 15.3 3.6 7.9 9.8 1.4 1 1 1 2 2 2 0 TCP family transcription factor Pex16 PF08610.5 CDI86402.1 - 4.2 6.2 7.4 5.1 6.0 5.2 1.1 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) MSP1_C PF07462.6 CDI86402.1 - 4.7 5.4 11.1 5.5 5.2 7.7 1.0 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus PAT1 PF09770.4 CDI86402.1 - 5.5 5.0 28.9 5.6 5.0 20.0 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Ctr PF04145.10 CDI86402.1 - 7.7 6.5 7.2 6.2 6.8 4.3 1.4 1 1 0 1 1 1 0 Ctr copper transporter family SR-25 PF10500.4 CDI86403.1 - 0.22 10.9 21.3 0.027 13.9 7.5 2.5 3 0 0 3 3 3 0 Nuclear RNA-splicing-associated protein eIF-3_zeta PF05091.7 CDI86404.1 - 0.0029 16.2 4.8 0.0029 16.2 3.3 3.0 3 0 0 3 3 3 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Cyto_ox_2 PF02322.10 CDI86404.1 - 0.31 10.1 4.0 0.51 9.4 2.8 1.2 1 0 0 1 1 1 0 Cytochrome oxidase subunit II FAM60A PF15396.1 CDI86404.1 - 0.48 10.1 49.2 0.22 11.2 8.2 3.1 3 0 0 3 3 3 0 Protein Family FAM60A SR-25 PF10500.4 CDI86404.1 - 6.8 6.0 99.6 0.21 11.0 20.9 3.5 3 1 0 3 3 3 0 Nuclear RNA-splicing-associated protein COX14 PF14880.1 CDI86405.1 - 3.5e-07 29.7 0.4 3.5e-07 29.7 0.3 5.4 3 2 0 3 3 3 1 Cytochrome oxidase c assembly SprA-related PF12118.3 CDI86405.1 - 0.0011 18.3 61.5 0.0014 18.0 42.6 1.1 1 0 0 1 1 1 1 SprA-related family PAT1 PF09770.4 CDI86405.1 - 0.021 13.1 70.4 0.022 13.0 48.8 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Ndc1_Nup PF09531.5 CDI86405.1 - 0.27 9.5 24.8 0.31 9.4 17.2 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Phage_holin_T PF11031.3 CDI86405.1 - 0.48 9.5 0.0 0.48 9.5 0.0 2.5 2 1 1 3 3 3 0 Bacteriophage T holin CAF-1_p150 PF11600.3 CDI86405.1 - 0.48 9.7 45.7 0.29 10.4 30.5 1.5 1 1 1 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal RAP1 PF07218.6 CDI86405.1 - 0.62 8.0 3.4 0.77 7.7 2.3 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) PCEMA1 PF07418.6 CDI86405.1 - 5.3 6.3 13.6 6.3 6.0 9.4 1.2 1 0 0 1 1 1 0 Acidic phosphoprotein precursor PCEMA1 SR-25 PF10500.4 CDI86406.1 - 0.0024 17.3 15.9 0.0024 17.3 11.0 7.3 5 1 2 7 7 7 3 Nuclear RNA-splicing-associated protein IncA PF04156.9 CDI86408.1 - 0.00014 21.5 8.5 0.00015 21.4 5.9 1.0 1 0 0 1 1 1 1 IncA protein CBF PF03914.12 CDI86408.1 - 0.033 13.6 1.5 0.034 13.5 1.0 1.1 1 0 0 1 1 1 0 CBF/Mak21 family CD20 PF04103.10 CDI86408.1 - 0.11 12.4 2.0 0.17 11.7 1.4 1.4 1 1 0 1 1 1 0 CD20-like family Spt20 PF12090.3 CDI86408.1 - 0.25 10.6 5.1 0.22 10.8 3.5 1.1 1 0 0 1 1 1 0 Spt20 family Peptidase_S49_N PF08496.5 CDI86408.1 - 0.34 10.6 6.2 0.36 10.6 4.3 1.0 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF2215 PF10225.4 CDI86408.1 - 0.47 9.8 4.0 0.5 9.7 2.8 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) DUF2195 PF09961.4 CDI86408.1 - 1 9.1 6.1 0.49 10.2 2.9 1.5 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2195) Shadoo PF14999.1 CDI86408.1 - 1 9.2 6.2 1.2 9.0 4.3 1.2 1 0 0 1 1 1 0 Shadow of prion protein, neuroprotective Activator_LAG-3 PF11498.3 CDI86408.1 - 1.1 7.9 22.2 1.1 7.9 15.4 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 TMEM51 PF15345.1 CDI86408.1 - 1.2 8.7 6.5 1.3 8.7 4.5 1.1 1 0 0 1 1 1 0 Transmembrane protein 51 Serinc PF03348.10 CDI86408.1 - 1.4 7.5 5.2 1.5 7.4 3.6 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) Peptidase_S15 PF02129.13 CDI86408.1 - 1.4 8.2 7.3 1.6 8.0 5.0 1.0 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) DUF2232 PF09991.4 CDI86408.1 - 1.5 7.7 5.5 1.7 7.5 3.8 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) Med15 PF09606.5 CDI86408.1 - 2.7 6.0 22.6 3 5.9 15.7 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal PP2C_2 PF13672.1 CDI86408.1 - 2.8 7.3 10.0 3.3 7.0 6.9 1.0 1 0 0 1 1 1 0 Protein phosphatase 2C SHR3_chaperone PF08229.6 CDI86408.1 - 5.8 5.8 7.9 5.8 5.8 5.5 1.1 1 0 0 1 1 1 0 ER membrane protein SH3 PMSI1 PF15322.1 CDI86408.1 - 6.6 5.7 9.1 7 5.6 6.3 1.0 1 0 0 1 1 1 0 Protein missing in infertile sperm 1, putative R_equi_Vir PF05526.6 CDI86408.1 - 6.7 6.3 9.1 7.7 6.1 6.3 1.1 1 0 0 1 1 1 0 Rhodococcus equi virulence-associated protein Chorion_S16 PF05836.7 CDI86408.1 - 9.1 6.2 8.7 11 5.9 6.1 1.2 1 0 0 1 1 1 0 Chorion protein S16 PAT1 PF09770.4 CDI86409.1 - 0.027 12.7 21.6 0.026 12.7 15.0 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DDHD PF02862.12 CDI86409.1 - 0.04 13.7 2.9 0.047 13.4 2.0 1.2 1 0 0 1 1 1 0 DDHD domain TFIIA PF03153.8 CDI86409.1 - 0.057 13.3 21.2 0.077 12.8 14.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4647 PF15504.1 CDI86409.1 - 0.16 10.8 10.7 0.24 10.2 7.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4647) 7tm_1 PF00001.16 CDI86409.1 - 0.19 10.8 0.1 0.31 10.1 0.1 1.2 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) RAB3GAP2_N PF14655.1 CDI86409.1 - 0.72 8.7 14.0 0.35 9.8 0.2 2.2 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus FANCI_S4 PF14678.1 CDI86409.1 - 0.91 8.5 13.4 0.61 9.1 8.0 1.6 1 1 0 1 1 1 0 FANCI solenoid 4 Spc24 PF08286.6 CDI86409.1 - 1.7 8.3 13.1 2.1 8.0 5.2 2.4 3 0 0 3 3 3 0 Spc24 subunit of Ndc80 Neur_chan_memb PF02932.11 CDI86409.1 - 3 7.6 4.8 4.2 7.1 3.4 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF2828 PF11443.3 CDI86409.1 - 3 5.9 9.8 4.3 5.4 6.8 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF2828) Spore_YhcN_YlaJ PF09580.5 CDI86409.1 - 3 7.9 8.0 5 7.1 5.5 1.3 1 0 0 1 1 1 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) PHD_3 PF13922.1 CDI86409.1 - 3.8 7.8 18.1 1.5 9.0 1.0 2.8 2 0 0 2 2 2 0 PHD domain of transcriptional enhancer, Asx dsDNA_bind PF01984.15 CDI86409.1 - 6.1 6.8 30.9 10 6.1 3.3 2.6 2 0 0 2 2 2 0 Double-stranded DNA-binding domain Bud13 PF09736.4 CDI86409.1 - 6.9 6.9 14.8 13 6.0 5.4 2.1 2 0 0 2 2 2 0 Pre-mRNA-splicing factor of RES complex Med15 PF09606.5 CDI86410.1 - 3.2e-05 22.3 61.8 0.0027 15.9 17.8 2.2 2 0 0 2 2 2 2 ARC105 or Med15 subunit of Mediator complex non-fungal BAF1_ABF1 PF04684.8 CDI86410.1 - 0.00019 20.4 16.7 0.00019 20.4 11.6 3.4 4 0 0 4 4 2 1 BAF1 / ABF1 chromatin reorganising factor DUF4207 PF13904.1 CDI86410.1 - 0.0025 17.2 25.1 0.032 13.6 4.9 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF4207) PAT1 PF09770.4 CDI86410.1 - 0.0075 14.5 42.5 0.059 11.6 10.0 2.0 2 0 0 2 2 2 2 Topoisomerase II-associated protein PAT1 HABP4_PAI-RBP1 PF04774.10 CDI86410.1 - 0.025 15.0 5.2 0.025 15.0 3.6 2.3 2 0 0 2 2 2 0 Hyaluronan / mRNA binding family DUF4557 PF15101.1 CDI86410.1 - 0.082 12.7 31.5 0.73 9.6 6.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4557) DUF1764 PF08576.5 CDI86410.1 - 0.15 12.8 15.8 1 10.1 3.3 2.4 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF1764) Gag_spuma PF03276.9 CDI86410.1 - 0.3 9.3 34.3 0.18 10.1 5.3 2.2 2 0 0 2 2 2 0 Spumavirus gag protein zf-DHHC PF01529.15 CDI86410.1 - 0.35 10.2 4.5 1.7 8.0 0.1 2.2 2 0 0 2 2 2 0 DHHC palmitoyltransferase EPL1 PF10513.4 CDI86410.1 - 0.55 10.4 15.3 2.8 8.1 2.4 2.2 2 0 0 2 2 2 0 Enhancer of polycomb-like Cryptochrome_C PF12546.3 CDI86410.1 - 0.7 10.5 21.3 0.82 10.3 5.4 2.7 2 0 0 2 2 2 0 Blue/Ultraviolet sensing protein C terminal FimP PF09766.4 CDI86410.1 - 0.77 8.7 34.1 0.23 10.4 7.7 2.1 2 0 0 2 2 2 0 Fms-interacting protein Anoctamin PF04547.7 CDI86410.1 - 0.79 8.3 3.8 3.7 6.0 0.0 2.0 2 0 0 2 2 2 0 Calcium-activated chloride channel PGA2 PF07543.7 CDI86410.1 - 1 9.1 9.8 3.2 7.5 0.8 2.6 2 0 0 2 2 2 0 Protein trafficking PGA2 FliP PF00813.15 CDI86410.1 - 1.2 8.7 6.8 1.4 8.5 0.4 2.2 2 0 0 2 2 2 0 FliP family Spt20 PF12090.3 CDI86410.1 - 1.2 8.4 18.9 0.95 8.7 3.8 2.3 2 0 0 2 2 2 0 Spt20 family DUF3371 PF11851.3 CDI86410.1 - 1.8 9.2 27.5 2.3 8.8 4.8 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3371) FLO_LFY PF01698.11 CDI86410.1 - 1.8 7.3 16.6 1.7 7.4 2.9 2.1 2 0 0 2 2 2 0 Floricaula / Leafy protein DUF605 PF04652.11 CDI86410.1 - 2 7.7 32.3 2.6 7.3 11.9 2.1 2 0 0 2 2 2 0 Vta1 like RR_TM4-6 PF06459.7 CDI86410.1 - 2.5 7.8 18.5 5.2 6.8 5.9 2.2 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Band_3_cyto PF07565.8 CDI86410.1 - 2.8 7.4 17.1 4 6.8 2.5 2.1 2 0 0 2 2 2 0 Band 3 cytoplasmic domain Dynamin_N PF00350.18 CDI86410.1 - 4.1 7.1 8.7 4.5 7.0 0.7 2.2 2 0 0 2 2 2 0 Dynamin family AUX_IAA PF02309.11 CDI86410.1 - 4.5 6.9 13.2 5.3 6.7 3.1 2.7 3 0 0 3 3 3 0 AUX/IAA family DUF912 PF06024.7 CDI86410.1 - 4.6 7.3 9.2 19 5.3 0.3 2.7 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Peptidase_C58 PF03543.9 CDI86410.1 - 6.4 6.2 25.9 3.1 7.2 4.9 2.3 2 0 0 2 2 2 0 Yersinia/Haemophilus virulence surface antigen ATAD4 PF15321.1 CDI86410.1 - 8 7.5 17.1 7.3 7.6 3.1 2.5 2 0 0 2 2 2 0 ATPase family AAA domain containing 4 Peptidase_S49_N PF08496.5 CDI86410.1 - 8.3 6.1 18.4 7.5 6.3 4.7 2.4 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Sec7 PF01369.15 CDI86411.1 - 0.0019 17.8 0.0 0.0036 17.0 0.0 1.3 1 0 0 1 1 1 1 Sec7 domain YajC PF02699.10 CDI86411.1 - 0.035 13.7 2.7 0.084 12.5 1.9 1.6 1 0 0 1 1 1 0 Preprotein translocase subunit EphA2_TM PF14575.1 CDI86411.1 - 0.24 11.8 0.1 0.24 11.8 0.1 2.3 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain STAS PF01740.16 CDI86413.1 - 7.8e-18 64.0 0.0 1.2e-17 63.3 0.0 1.3 1 0 0 1 1 1 1 STAS domain Sulfate_transp PF00916.15 CDI86413.1 - 0.00037 19.5 0.3 0.00055 19.0 0.0 1.4 2 0 0 2 2 2 1 Sulfate transporter family STAS_2 PF13466.1 CDI86413.1 - 0.0018 18.2 0.0 0.0077 16.2 0.0 2.2 1 0 0 1 1 1 1 STAS domain MKT1_C PF12246.3 CDI86414.1 - 0.012 14.6 4.3 0.088 11.7 0.3 2.0 1 1 1 2 2 2 0 Temperature dependent protein affecting M2 dsRNA replication DUF3515 PF12028.3 CDI86414.1 - 0.034 13.3 4.5 0.2 10.8 0.7 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3515) Apc1 PF12859.2 CDI86414.1 - 0.3 11.3 19.7 1 9.5 6.5 2.2 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 1 DUF4642 PF15484.1 CDI86414.1 - 0.37 10.7 8.8 0.5 10.3 6.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4642) Spore_YhcN_YlaJ PF09580.5 CDI86414.1 - 0.99 9.4 7.9 1.2 9.2 5.5 1.2 1 0 0 1 1 1 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) Neur_chan_memb PF02932.11 CDI86414.1 - 1 9.1 8.3 1.1 9.1 5.8 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Folate_carrier PF01770.13 CDI86414.1 - 1.3 7.5 7.8 1.4 7.3 5.4 1.0 1 0 0 1 1 1 0 Reduced folate carrier BNR_3 PF13859.1 CDI86414.1 - 1.5 7.8 5.1 1.8 7.5 3.5 1.0 1 0 0 1 1 1 0 BNR repeat-like domain HABP4_PAI-RBP1 PF04774.10 CDI86414.1 - 1.9 9.0 10.5 0.2 12.1 3.3 1.8 2 0 0 2 2 2 0 Hyaluronan / mRNA binding family Neurensin PF14927.1 CDI86414.1 - 2 7.8 5.6 7.2 5.9 0.3 2.6 1 1 1 3 3 3 0 Neurensin Serinc PF03348.10 CDI86414.1 - 2.5 6.7 7.0 2.7 6.5 4.9 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) FHIPEP PF00771.15 CDI86414.1 - 3.2 5.9 9.9 3.7 5.7 6.8 1.1 1 0 0 1 1 1 0 FHIPEP family DUF2782 PF11191.3 CDI86414.1 - 4.8 7.1 8.4 1.2e+02 2.7 5.7 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2782) Afi1 PF07792.7 CDI86414.1 - 5 7.1 12.4 6.7 6.7 8.6 1.2 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Pan_kinase PF03309.9 CDI86414.1 - 6.2 6.2 10.0 2.1 7.7 5.0 1.5 1 1 1 2 2 2 0 Type III pantothenate kinase Band_3_cyto PF07565.8 CDI86414.1 - 6.3 6.2 17.6 7.8 5.9 12.2 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain RuvB_N PF05496.7 CDI86414.1 - 8.5 5.3 7.4 14 4.6 5.1 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus DUF3530 PF12048.3 CDI86414.1 - 8.9 5.1 24.5 20 4.0 17.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3530) RskA PF10099.4 CDI86416.1 - 0.013 15.2 3.2 0.024 14.3 2.2 1.4 1 0 0 1 1 1 0 Anti-sigma-K factor rskA SprA-related PF12118.3 CDI86416.1 - 0.035 13.4 22.4 0.045 13.0 15.5 1.1 1 0 0 1 1 1 0 SprA-related family Zip PF02535.17 CDI86416.1 - 0.087 11.8 8.2 0.11 11.4 5.7 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter MTBP_C PF14920.1 CDI86416.1 - 0.12 11.8 15.4 0.16 11.4 10.7 1.0 1 0 0 1 1 1 0 MDM2-binding OmpH PF03938.9 CDI86416.1 - 0.26 11.2 16.9 0.46 10.4 11.7 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) RAP1 PF07218.6 CDI86416.1 - 0.55 8.2 2.2 0.61 8.1 1.5 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) PAT1 PF09770.4 CDI86416.1 - 0.97 7.5 26.3 0.96 7.6 18.2 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Ribosomal_60s PF00428.14 CDI86416.1 - 1.3 9.4 8.8 0.076 13.4 2.4 1.7 2 0 0 2 2 1 0 60s Acidic ribosomal protein R_equi_Vir PF05526.6 CDI86416.1 - 6.4 6.3 8.8 2.2 7.8 3.2 1.9 2 0 0 2 2 2 0 Rhodococcus equi virulence-associated protein TFIIA PF03153.8 CDI86416.1 - 6.7 6.4 27.1 8.5 6.1 18.8 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Pap_E4 PF02711.9 CDI86416.1 - 9.1 7.1 15.8 16 6.3 6.7 2.3 2 0 0 2 2 2 0 E4 protein PAT1 PF09770.4 CDI86417.1 - 1.5 6.9 25.0 1.9 6.6 17.3 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Sel1 PF08238.7 CDI86421.1 - 4.1e-25 87.6 27.8 1.2e-05 25.8 0.0 10.9 11 0 0 11 11 11 8 Sel1 repeat HSP20 PF00011.16 CDI86422.1 - 9.6e-19 67.1 0.0 1.4e-18 66.6 0.0 1.2 1 0 0 1 1 1 1 Hsp20/alpha crystallin family Kinesin PF00225.18 CDI86423.1 - 4.9e-29 101.0 0.0 1.1e-20 73.6 0.0 2.6 3 0 0 3 3 3 2 Kinesin motor domain CagX PF03524.10 CDI86423.1 - 0.62 9.2 0.2 1.4 8.1 0.1 1.5 1 0 0 1 1 1 0 Conjugal transfer protein CDC27 PF09507.5 CDI86424.1 - 0.089 12.0 19.6 0.13 11.4 13.6 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 zf-RING_2 PF13639.1 CDI86426.1 - 5.1e-11 42.2 10.6 3.8e-10 39.4 2.5 3.4 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4_2 PF13923.1 CDI86426.1 - 9.2e-09 35.1 5.9 8.9e-08 32.0 2.0 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CDI86426.1 - 6.7e-08 32.1 6.7 1.2e-07 31.3 1.3 2.6 2 0 0 2 2 2 1 zinc-RING finger domain zf-rbx1 PF12678.2 CDI86426.1 - 3.2e-07 30.3 1.5 9.9e-06 25.5 0.1 2.6 2 0 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 CDI86426.1 - 1.1e-06 28.1 3.1 1.1e-06 28.1 2.1 2.5 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CDI86426.1 - 2.5e-06 27.0 6.9 6.4e-06 25.7 1.1 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 CDI86426.1 - 0.0014 18.3 0.8 0.0014 18.3 0.6 2.8 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 CDI86426.1 - 0.007 16.2 5.9 0.0075 16.1 1.5 2.6 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-Apc11 PF12861.2 CDI86426.1 - 0.068 13.0 0.5 0.2 11.5 0.3 1.8 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 CDI86426.1 - 0.12 12.0 5.9 0.038 13.5 0.7 2.2 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-Nse PF11789.3 CDI86426.1 - 0.29 10.6 3.6 0.13 11.8 0.7 1.7 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit Prok-RING_4 PF14447.1 CDI86426.1 - 1.9 8.1 5.1 3.5 7.2 0.8 2.8 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_6 PF14835.1 CDI86426.1 - 2.5 7.9 6.1 0.3 10.8 0.8 2.0 2 0 0 2 2 2 0 zf-RING of BARD1-type protein SAGA-Tad1 PF12767.2 CDI86426.1 - 4.4 6.9 39.0 0.95 9.0 10.0 3.5 3 0 0 3 3 3 0 Transcriptional regulator of RNA polII, SAGA, subunit MatC_N PF07158.6 CDI86427.1 - 0.00037 20.3 0.2 0.97 9.2 0.0 2.1 2 0 0 2 2 2 2 Dicarboxylate carrier protein MatC N-terminus CD99L2 PF12301.3 CDI86427.1 - 0.18 11.5 13.9 0.92 9.1 0.0 3.1 2 1 0 2 2 2 0 CD99 antigen like protein 2 T2SF PF00482.18 CDI86427.1 - 0.22 11.4 0.1 0.22 11.4 0.0 3.6 4 0 0 4 4 4 0 Type II secretion system (T2SS), protein F UPF0164 PF03687.8 CDI86427.1 - 0.64 8.4 4.2 8.1 4.8 0.1 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0164) UPF0233 PF06781.7 CDI86427.1 - 3.1 7.4 0.0 3.1 7.4 0.0 3.9 4 1 0 4 4 4 0 Uncharacterised protein family (UPF0233) ETRAMP PF09716.5 CDI86427.1 - 8.1 6.4 9.0 4.9 7.1 1.4 2.8 2 1 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) SseC PF04888.7 CDI86428.1 - 0.0002 20.8 33.9 0.0002 20.8 23.5 5.4 5 1 0 5 5 5 2 Secretion system effector C (SseC) like family CDC45 PF02724.9 CDI86428.1 - 2.1 6.3 25.0 0.2 9.6 1.3 3.1 3 0 0 3 3 3 0 CDC45-like protein Neur_chan_memb PF02932.11 CDI86430.1 - 0.72 9.6 0.0 0.72 9.6 0.0 9.2 5 3 1 6 6 6 0 Neurotransmitter-gated ion-channel transmembrane region N6_N4_Mtase PF01555.13 CDI86430.1 - 1.7 8.0 5.6 38 3.6 0.8 4.8 6 1 0 6 6 6 0 DNA methylase Ycf1 PF05758.7 CDI86431.1 - 0.076 10.7 14.5 0.082 10.6 10.0 1.0 1 0 0 1 1 1 0 Ycf1 DUF1183 PF06682.7 CDI86431.1 - 0.16 11.5 17.0 0.21 11.1 11.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) SseC PF04888.7 CDI86431.1 - 0.22 10.8 39.4 0.27 10.5 27.3 1.1 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family PAT1 PF09770.4 CDI86431.1 - 0.86 7.7 42.7 0.94 7.6 29.6 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Nop25 PF09805.4 CDI86431.1 - 1.2 9.2 22.2 2 8.5 15.4 1.4 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) Exonuc_VII_L PF02601.10 CDI86431.1 - 4 6.5 26.2 6.3 5.8 18.2 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF2217 PF10265.4 CDI86431.1 - 7.2 5.2 20.6 13 4.4 14.3 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) MIP-T3 PF10243.4 CDI86432.1 - 4.2e-05 22.2 67.2 5.8e-05 21.7 46.5 1.1 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 Utp14 PF04615.8 CDI86432.1 - 0.00061 18.0 58.6 0.00068 17.9 40.6 1.1 1 0 0 1 1 1 1 Utp14 protein Daxx PF03344.10 CDI86432.1 - 0.0036 15.8 44.4 0.0041 15.6 30.8 1.1 1 0 0 1 1 1 1 Daxx Family Asp-B-Hydro_N PF05279.6 CDI86432.1 - 0.19 11.5 46.2 0.26 11.1 32.0 1.3 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region DUF3995 PF13160.1 CDI86435.1 - 0.19 11.7 2.4 0.65 10.0 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3995) Herpes_gE PF02480.11 CDI86436.1 - 0.057 11.6 3.1 0.067 11.4 2.1 1.0 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E DUF3439 PF11921.3 CDI86436.1 - 0.059 13.1 0.2 0.07 12.8 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Tcp11 PF05794.8 CDI86436.1 - 0.072 11.7 9.6 0.073 11.7 6.7 1.0 1 0 0 1 1 1 0 T-complex protein 11 BAF1_ABF1 PF04684.8 CDI86436.1 - 0.15 10.8 26.3 0.18 10.6 18.3 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor SPX PF03105.14 CDI86436.1 - 0.23 11.2 11.9 0.29 10.8 8.3 1.2 1 0 0 1 1 1 0 SPX domain SGT1 PF07093.6 CDI86436.1 - 0.57 8.4 11.2 0.68 8.2 7.8 1.0 1 0 0 1 1 1 0 SGT1 protein Peptidase_S64 PF08192.6 CDI86436.1 - 0.58 8.4 9.8 0.57 8.4 6.8 1.0 1 0 0 1 1 1 0 Peptidase family S64 DUF2248 PF10005.4 CDI86436.1 - 0.58 9.0 7.1 0.66 8.8 4.9 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2248) Mucin PF01456.12 CDI86436.1 - 0.69 9.6 17.6 0.89 9.3 12.2 1.1 1 0 0 1 1 1 0 Mucin-like glycoprotein CDK2AP PF09806.4 CDI86436.1 - 0.82 9.8 24.4 1 9.5 16.9 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein Herpes_TAF50 PF03326.8 CDI86436.1 - 0.95 8.3 14.3 0.93 8.3 9.9 1.1 1 0 0 1 1 1 0 Herpesvirus transcription activation factor (transactivator) Herpes_capsid PF06112.6 CDI86436.1 - 0.97 9.4 9.3 1.5 8.8 6.5 1.3 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein PCNP PF15473.1 CDI86436.1 - 1.3 9.3 7.5 2.4 8.4 5.2 1.4 1 0 0 1 1 1 0 PEST, proteolytic signal-containing nuclear protein family FAM60A PF15396.1 CDI86436.1 - 1.4 8.5 5.2 1.5 8.5 3.6 1.2 1 0 0 1 1 1 0 Protein Family FAM60A Med15 PF09606.5 CDI86436.1 - 1.5 6.9 33.1 2.1 6.4 22.9 1.3 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal LCD1 PF09798.4 CDI86436.1 - 1.5 6.7 7.4 1.4 6.8 5.1 1.2 1 0 0 1 1 1 0 DNA damage checkpoint protein DUF4613 PF15390.1 CDI86436.1 - 1.8 6.6 8.6 2 6.4 6.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) MSP1_C PF07462.6 CDI86436.1 - 1.9 6.8 9.1 2 6.7 6.3 1.1 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Glyco_transf_15 PF01793.11 CDI86436.1 - 2.5 6.9 8.4 2.5 6.9 5.8 1.2 1 0 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase DUF966 PF06136.8 CDI86436.1 - 2.5 7.4 12.5 2.7 7.3 8.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) DUF3153 PF11353.3 CDI86436.1 - 2.7 7.4 9.8 3.1 7.1 6.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3153) Hist_deacetyl PF00850.14 CDI86436.1 - 2.7 7.2 5.9 3.1 6.9 4.1 1.2 1 0 0 1 1 1 0 Histone deacetylase domain Peptidase_S15 PF02129.13 CDI86436.1 - 3.8 6.8 11.7 4.7 6.5 8.1 1.1 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Draxin PF15550.1 CDI86436.1 - 3.9 7.0 8.1 4.4 6.8 5.6 1.3 1 0 0 1 1 1 0 Draxin bHLH-MYC_N PF14215.1 CDI86436.1 - 4.1 7.5 7.7 5.6 7.1 5.4 1.1 1 0 0 1 1 1 0 bHLH-MYC and R2R3-MYB transcription factors N-terminal DUF4638 PF15472.1 CDI86436.1 - 4.2 6.8 7.1 5.1 6.5 4.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) Spc24 PF08286.6 CDI86436.1 - 4.2 7.0 18.8 0.61 9.7 1.0 2.1 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 Pex16 PF08610.5 CDI86436.1 - 4.6 6.1 9.2 5.4 5.9 6.4 1.1 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) MCPVI PF02993.9 CDI86436.1 - 4.9 7.2 11.5 5.9 6.9 8.0 1.2 1 0 0 1 1 1 0 Minor capsid protein VI Ndc1_Nup PF09531.5 CDI86436.1 - 5.8 5.2 8.7 6.1 5.1 6.1 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Hid1 PF12722.2 CDI86436.1 - 6.1 4.3 11.3 5.7 4.4 7.8 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Gag_spuma PF03276.9 CDI86436.1 - 6.8 4.8 13.8 7.5 4.7 9.5 1.2 1 0 0 1 1 1 0 Spumavirus gag protein PAT1 PF09770.4 CDI86436.1 - 6.9 4.7 23.3 8.7 4.4 16.2 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF2201_N PF13203.1 CDI86436.1 - 7.9 5.5 17.8 8.9 5.3 12.3 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain TSKS PF15358.1 CDI86436.1 - 8 4.4 15.9 9.1 4.3 11.0 1.0 1 0 0 1 1 1 0 Testis-specific serine kinase substrate Neur_chan_memb PF02932.11 CDI86436.1 - 9.3 6.0 6.1 9.4 6.0 4.3 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF2359 PF10151.4 CDI86436.1 - 9.8 4.5 7.8 11 4.3 5.4 1.0 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2359) Shadoo PF14999.1 CDI86437.1 - 0.0072 16.1 4.6 0.0091 15.8 3.2 1.2 1 0 0 1 1 1 1 Shadow of prion protein, neuroprotective SR-25 PF10500.4 CDI86437.1 - 0.013 14.9 23.6 0.017 14.5 16.4 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein CDK2AP PF09806.4 CDI86437.1 - 0.69 10.1 30.1 0.85 9.8 20.8 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein DUF3720 PF12517.3 CDI86437.1 - 2.3 8.9 16.8 0.52 11.0 9.4 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3720) CAF-1_p150 PF11600.3 CDI86437.1 - 2.7 7.3 23.5 0.23 10.8 12.9 1.6 1 1 1 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Herpes_capsid PF06112.6 CDI86437.1 - 3.5 7.6 20.8 4.4 7.3 14.4 1.2 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein MSP1_C PF07462.6 CDI86437.1 - 5.9 5.1 10.2 6.2 5.0 7.1 1.1 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus DUF755 PF05501.6 CDI86437.1 - 6.3 6.8 37.4 1.2 9.2 17.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF755) Corona_nucleoca PF00937.13 CDI86437.1 - 8.7 5.1 25.2 10 4.9 17.5 1.1 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein SprA-related PF12118.3 CDI86438.1 - 3.7e-05 23.2 36.0 3.7e-05 23.2 24.9 2.2 2 0 0 2 2 2 1 SprA-related family Macoilin PF09726.4 CDI86438.1 - 0.00015 20.2 27.9 0.00015 20.2 19.3 2.0 2 0 0 2 2 2 1 Transmembrane protein FimP PF09766.4 CDI86438.1 - 0.00028 20.0 6.3 0.00028 20.0 4.4 1.5 2 0 0 2 2 2 1 Fms-interacting protein SPX PF03105.14 CDI86438.1 - 0.002 17.9 14.8 0.033 13.9 3.3 2.2 2 0 0 2 2 2 2 SPX domain DHH PF01368.15 CDI86438.1 - 0.013 15.1 0.0 0.025 14.2 0.0 1.5 1 0 0 1 1 1 0 DHH family Plasmodium_Vir PF05795.6 CDI86438.1 - 0.097 11.8 16.2 0.033 13.4 0.4 2.0 2 0 0 2 2 2 0 Plasmodium vivax Vir protein RED_N PF07808.8 CDI86438.1 - 0.31 10.2 17.9 0.052 12.7 9.2 1.9 1 1 1 2 2 2 0 RED-like protein N-terminal region Nucleoside_tran PF01733.13 CDI86438.1 - 0.69 9.0 3.3 0.17 11.0 0.1 1.6 2 0 0 2 2 2 0 Nucleoside transporter CPSF100_C PF13299.1 CDI86438.1 - 3.3 7.8 16.3 0.25 11.5 1.1 3.0 3 0 0 3 3 3 0 Cleavage and polyadenylation factor 2 C-terminal DUF912 PF06024.7 CDI86438.1 - 6.2 6.9 10.7 0.37 10.8 0.5 3.1 3 1 0 3 3 3 0 Nucleopolyhedrovirus protein of unknown function (DUF912) EphA2_TM PF14575.1 CDI86438.1 - 9.5 6.6 5.9 3.2 8.2 1.0 2.5 3 0 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain Toxin_41 PF15521.1 CDI86439.1 - 0.11 11.6 2.4 0.12 11.4 1.7 1.1 1 0 0 1 1 1 0 Putative toxin 41 ATG22 PF11700.3 CDI86439.1 - 0.67 8.3 3.5 0.25 9.7 0.1 1.7 2 0 0 2 2 2 0 Vacuole effluxer Atg22 like Cyclin_C PF02984.14 CDI86439.1 - 3.5 7.6 10.5 10 6.1 7.3 1.7 1 1 0 1 1 1 0 Cyclin, C-terminal domain MOSP_N PF02707.11 CDI86439.1 - 6.8 6.2 6.1 0.82 9.2 0.7 1.8 1 1 1 2 2 2 0 Major Outer Sheath Protein N-terminal region RskA PF10099.4 CDI86439.1 - 8.1 6.1 14.9 0.18 11.5 2.9 2.1 2 0 0 2 2 2 0 Anti-sigma-K factor rskA FimP PF09766.4 CDI86439.1 - 9.2 5.2 18.4 4.9 6.1 4.7 2.0 2 0 0 2 2 2 0 Fms-interacting protein FAM196 PF15265.1 CDI86440.1 - 2.4 7.3 30.8 2.7 7.1 21.3 1.0 1 0 0 1 1 1 0 FAM196 family IncA PF04156.9 CDI86441.1 - 0.0016 18.0 53.8 0.002 17.7 37.3 1.1 1 0 0 1 1 1 1 IncA protein DUF4175 PF13779.1 CDI86441.1 - 0.015 13.0 70.3 0.017 12.8 48.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) FUSC PF04632.7 CDI86441.1 - 0.079 11.3 21.1 0.09 11.1 14.7 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family E2F_TDP PF02319.15 CDI86441.1 - 0.14 11.7 0.6 0.44 10.1 0.3 1.9 1 1 1 2 2 2 0 E2F/DP family winged-helix DNA-binding domain RNA_pol_Rpb1_1 PF04997.7 CDI86441.1 - 0.18 11.0 16.9 0.23 10.6 11.7 1.0 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 1 WES_acyltransf PF03007.11 CDI86441.1 - 0.37 10.3 14.1 0.52 9.8 9.8 1.3 1 0 0 1 1 1 0 Wax ester synthase-like Acyl-CoA acyltransferase domain LANC_like PF05147.8 CDI86441.1 - 0.5 8.8 3.0 0.7 8.3 2.0 1.3 1 1 0 1 1 1 0 Lanthionine synthetase C-like protein PLRV_ORF5 PF01690.12 CDI86441.1 - 0.56 9.2 27.2 0.72 8.9 18.9 1.0 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Pterin_bind PF00809.17 CDI86441.1 - 0.68 9.2 5.7 0.098 12.0 0.8 1.8 1 1 1 2 2 2 0 Pterin binding enzyme DUF4407 PF14362.1 CDI86441.1 - 0.73 8.7 47.3 0.87 8.4 32.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) AIP3 PF03915.8 CDI86441.1 - 5.3 5.8 30.9 6.7 5.5 21.4 1.1 1 0 0 1 1 1 0 Actin interacting protein 3 NARP1 PF12569.3 CDI86442.1 - 0.0022 16.8 15.9 0.0024 16.6 11.0 1.0 1 0 0 1 1 1 1 NMDA receptor-regulated protein 1 SUFU_C PF12470.3 CDI86442.1 - 0.01 15.4 9.4 0.012 15.1 6.5 1.1 1 0 0 1 1 1 0 Suppressor of Fused Gli/Ci N terminal binding domain DUF2828 PF11443.3 CDI86442.1 - 0.064 11.4 13.3 0.067 11.3 9.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) DDHD PF02862.12 CDI86442.1 - 0.069 12.9 16.2 0.077 12.7 11.3 1.1 1 0 0 1 1 1 0 DDHD domain DUF4045 PF13254.1 CDI86442.1 - 0.073 12.3 17.6 0.079 12.2 12.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) DUF1764 PF08576.5 CDI86442.1 - 0.084 13.6 22.1 0.14 12.9 15.3 1.3 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) Herpes_Helicase PF02689.9 CDI86442.1 - 0.091 10.4 10.5 0.11 10.2 7.3 1.0 1 0 0 1 1 1 0 Helicase FLO_LFY PF01698.11 CDI86442.1 - 0.13 11.0 17.6 0.14 10.9 12.2 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein SpoIIP PF07454.6 CDI86442.1 - 0.37 9.9 20.0 0.47 9.5 13.9 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Baculo_PP31 PF05311.6 CDI86442.1 - 0.5 9.5 18.0 0.6 9.3 12.5 1.3 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) GAGA_bind PF06217.7 CDI86442.1 - 0.7 9.8 20.7 0.76 9.6 14.3 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family Rtf2 PF04641.7 CDI86442.1 - 0.96 8.5 21.7 1.1 8.3 15.1 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger Hid1 PF12722.2 CDI86442.1 - 0.97 7.0 23.5 1 6.9 16.3 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein CDC45 PF02724.9 CDI86442.1 - 1 7.2 23.4 1.3 6.9 16.2 1.0 1 0 0 1 1 1 0 CDC45-like protein MSA-2c PF12238.3 CDI86442.1 - 1.1 8.8 15.7 1.5 8.4 10.9 1.2 1 0 0 1 1 1 0 Merozoite surface antigen 2c RR_TM4-6 PF06459.7 CDI86442.1 - 1.3 8.8 22.3 1.4 8.7 15.4 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 FAM60A PF15396.1 CDI86442.1 - 1.3 8.6 19.3 1.6 8.4 13.3 1.2 1 0 0 1 1 1 0 Protein Family FAM60A PAT1 PF09770.4 CDI86442.1 - 1.6 6.8 62.0 1.8 6.6 43.0 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 GPCR_chapero_1 PF11904.3 CDI86442.1 - 1.8 7.6 20.4 2.1 7.4 14.1 1.1 1 0 0 1 1 1 0 GPCR-chaperone DHHW PF14286.1 CDI86442.1 - 1.8 7.7 17.5 2 7.6 12.1 1.1 1 0 0 1 1 1 0 DHHW protein Adaptin_binding PF10199.4 CDI86442.1 - 2.1 8.6 23.1 2.7 8.2 16.0 1.2 1 0 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 F-protein PF00469.15 CDI86442.1 - 2.1 7.6 24.8 2.7 7.3 17.2 1.1 1 0 0 1 1 1 0 Negative factor, (F-Protein) or Nef Zip PF02535.17 CDI86442.1 - 2.2 7.2 7.8 2.4 7.0 5.4 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Topoisom_I_N PF02919.10 CDI86442.1 - 2.4 7.4 22.3 93 2.1 15.4 2.0 1 1 0 1 1 1 0 Eukaryotic DNA topoisomerase I, DNA binding fragment Tim54 PF11711.3 CDI86442.1 - 2.4 6.6 14.8 2.8 6.4 10.3 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 AAA_23 PF13476.1 CDI86442.1 - 2.4 8.4 31.7 3 8.1 22.0 1.3 1 0 0 1 1 1 0 AAA domain AUX_IAA PF02309.11 CDI86442.1 - 2.5 7.8 19.5 3.2 7.4 13.5 1.2 1 0 0 1 1 1 0 AUX/IAA family TFIIA PF03153.8 CDI86442.1 - 2.6 7.8 45.2 2.9 7.7 31.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF2370 PF10176.4 CDI86442.1 - 2.6 7.3 14.0 3.4 6.9 9.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) Band_3_cyto PF07565.8 CDI86442.1 - 2.7 7.4 22.8 3.4 7.1 15.8 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain VID27 PF08553.5 CDI86442.1 - 2.7 6.0 19.8 3.1 5.9 13.8 1.0 1 0 0 1 1 1 0 VID27 cytoplasmic protein CPSF100_C PF13299.1 CDI86442.1 - 2.8 8.1 18.8 3.5 7.8 13.0 1.3 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal CKAP2_C PF15297.1 CDI86442.1 - 2.9 6.6 26.6 3.5 6.3 18.4 1.0 1 0 0 1 1 1 0 Cytoskeleton-associated protein 2 C-terminus DUF966 PF06136.8 CDI86442.1 - 3.1 7.1 20.7 3.7 6.8 14.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) SARG PF15385.1 CDI86442.1 - 3.2 7.0 28.0 3.5 6.8 19.4 1.0 1 0 0 1 1 1 0 Specifically androgen-regulated gene protein DUF853 PF05872.7 CDI86442.1 - 3.3 5.9 18.3 3.9 5.7 12.7 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) SAPS PF04499.10 CDI86442.1 - 3.4 6.2 21.2 3.9 6.0 14.7 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Senescence_reg PF04520.8 CDI86442.1 - 3.4 8.1 14.1 4.5 7.7 9.8 1.2 1 0 0 1 1 1 0 Senescence regulator FYDLN_acid PF09538.5 CDI86442.1 - 4.1 8.0 9.7 5.8 7.5 6.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) Peptidase_S49_N PF08496.5 CDI86442.1 - 4.3 7.1 26.3 5.7 6.7 18.2 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF2201_N PF13203.1 CDI86442.1 - 4.7 6.3 23.4 4.7 6.2 16.2 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain Init_tRNA_PT PF04179.7 CDI86442.1 - 4.8 5.9 17.7 6.2 5.5 12.2 1.0 1 0 0 1 1 1 0 Initiator tRNA phosphoribosyl transferase FAM91_C PF14648.1 CDI86442.1 - 4.8 5.9 11.5 5.7 5.6 8.0 1.1 1 0 0 1 1 1 0 FAM91 C-terminus PCEMA1 PF07418.6 CDI86442.1 - 4.9 6.4 13.7 5.9 6.1 9.5 1.1 1 0 0 1 1 1 0 Acidic phosphoprotein precursor PCEMA1 Plasmodium_Vir PF05795.6 CDI86442.1 - 5 6.2 9.3 5.4 6.1 6.4 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein eIF-3_zeta PF05091.7 CDI86442.1 - 5.5 5.4 28.8 6 5.3 19.9 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Spore_coat_CotO PF14153.1 CDI86442.1 - 5.9 6.2 34.5 7.5 5.9 23.9 1.2 1 0 0 1 1 1 0 Spore coat protein CotO HGTP_anticodon2 PF12745.2 CDI86442.1 - 6.1 5.8 22.0 8 5.5 15.2 1.2 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs CobT PF06213.7 CDI86442.1 - 6.2 5.8 16.0 7.2 5.6 11.1 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Cellulose_synt PF03552.9 CDI86442.1 - 6.6 4.8 12.9 7.4 4.7 9.0 1.0 1 0 0 1 1 1 0 Cellulose synthase Abi_2 PF07751.6 CDI86442.1 - 7 6.7 10.5 9.3 6.3 7.3 1.2 1 0 0 1 1 1 0 Abi-like protein Cyto_heme_lyase PF01265.12 CDI86442.1 - 7.1 6.1 25.7 8.7 5.8 17.8 1.1 1 0 0 1 1 1 0 Cytochrome c/c1 heme lyase DUF3381 PF11861.3 CDI86442.1 - 7.9 5.9 22.6 11 5.5 15.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) G-patch_2 PF12656.2 CDI86442.1 - 8.5 6.3 17.9 4.3e+03 -2.4 12.4 3.0 1 1 0 1 1 0 0 DExH-box splicing factor binding site PA26 PF04636.8 CDI86442.1 - 8.5 4.9 19.6 10 4.6 13.6 1.0 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) RNA_pol_Rpb1_5 PF04998.12 CDI86442.1 - 9 5.4 14.6 10 5.2 10.1 1.1 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 DUF913 PF06025.7 CDI86442.1 - 9.3 4.8 13.1 11 4.6 9.1 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) GAGA_bind PF06217.7 CDI86443.1 - 0.53 10.1 36.0 0.23 11.3 12.2 2.2 2 0 0 2 2 2 0 GAGA binding protein-like family Neur_chan_memb PF02932.11 CDI86443.1 - 1.1 9.1 28.4 0.071 12.9 1.5 2.2 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region CDC45 PF02724.9 CDI86443.1 - 1.1 7.2 33.7 0.48 8.3 11.2 2.1 2 0 0 2 2 2 0 CDC45-like protein TT_ORF1 PF02956.9 CDI86443.1 - 3.7 5.9 22.7 0.19 10.1 1.1 2.2 2 0 0 2 2 2 0 TT viral orf 1 Med15 PF09606.5 CDI86444.1 - 0.012 13.8 50.9 0.093 10.9 18.3 2.1 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal Ribosomal_60s PF00428.14 CDI86444.1 - 0.48 10.8 14.8 1.1 9.6 10.3 1.6 1 0 0 1 1 1 0 60s Acidic ribosomal protein HemX PF04375.9 CDI86444.1 - 3 6.3 34.8 0.95 7.9 13.2 2.1 2 0 0 2 2 2 0 HemX HdeA PF06411.6 CDI86444.1 - 4.3 7.3 10.0 0.27 11.2 2.2 2.3 3 0 0 3 3 3 0 HdeA/HdeB family DUF2203 PF09969.4 CDI86444.1 - 4.7 7.4 12.8 0.29 11.3 0.4 2.9 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2203) Oleosin PF01277.12 CDI86444.1 - 6.3 6.3 8.1 7.1 6.2 0.7 2.8 2 1 1 3 3 3 0 Oleosin APC_CDC26 PF10471.4 CDI86444.1 - 10 6.9 52.0 0.29 11.8 10.3 3.5 3 0 0 3 3 3 0 Anaphase-promoting complex APC subunit 1 Spore_coat_CotO PF14153.1 CDI86445.1 - 0.0018 17.7 9.3 0.0019 17.7 6.5 1.1 1 0 0 1 1 1 1 Spore coat protein CotO eIF-3_zeta PF05091.7 CDI86445.1 - 0.0024 16.5 7.1 0.0024 16.5 4.9 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Ycf1 PF05758.7 CDI86445.1 - 0.0053 14.5 2.7 0.0051 14.5 1.9 1.0 1 0 0 1 1 1 1 Ycf1 Gti1_Pac2 PF09729.4 CDI86445.1 - 0.047 13.5 2.0 0.051 13.4 1.4 1.2 1 0 0 1 1 1 0 Gti1/Pac2 family FAM60A PF15396.1 CDI86445.1 - 0.078 12.7 3.1 0.079 12.7 2.1 1.1 1 0 0 1 1 1 0 Protein Family FAM60A DUF106 PF01956.11 CDI86445.1 - 0.12 11.9 1.9 0.11 12.0 1.3 1.2 1 0 0 1 1 1 0 Integral membrane protein DUF106 Hid1 PF12722.2 CDI86445.1 - 0.21 9.2 8.0 0.21 9.2 5.5 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF3824 PF12868.2 CDI86445.1 - 0.26 12.2 24.9 0.42 11.5 17.3 1.3 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) BRF1 PF07741.8 CDI86445.1 - 0.39 10.9 9.4 2.3 8.5 6.5 2.0 1 1 0 1 1 1 0 Brf1-like TBP-binding domain Bul1_N PF04425.7 CDI86445.1 - 0.59 8.6 8.1 0.6 8.6 5.6 1.1 1 0 0 1 1 1 0 Bul1 N terminus Neur_chan_memb PF02932.11 CDI86445.1 - 0.62 9.9 8.7 0.66 9.8 6.0 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region FUSC PF04632.7 CDI86445.1 - 0.65 8.3 7.1 0.82 8.0 4.9 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Calsarcin PF05556.6 CDI86445.1 - 1.5 7.9 11.5 1.6 7.8 8.0 1.1 1 0 0 1 1 1 0 Calcineurin-binding protein (Calsarcin) AUX_IAA PF02309.11 CDI86445.1 - 1.7 8.3 8.3 2 8.0 5.8 1.2 1 0 0 1 1 1 0 AUX/IAA family DUF4045 PF13254.1 CDI86445.1 - 1.7 7.8 11.1 1.9 7.6 7.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) TFIIA PF03153.8 CDI86445.1 - 1.8 8.4 29.6 2.1 8.1 20.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Lin-8 PF03353.10 CDI86445.1 - 2.2 7.4 15.1 2.5 7.3 10.4 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist BBS2_C PF14782.1 CDI86445.1 - 4.7 5.6 16.8 5.8 5.3 11.6 1.1 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, C-terminal Innate_immun PF12782.2 CDI86445.1 - 4.9 6.2 15.2 5.6 6.0 10.5 1.2 1 0 0 1 1 1 0 Invertebrate innate immunity transcript family AvrE PF11725.3 CDI86445.1 - 5.3 3.9 14.6 5.7 3.8 10.1 1.1 1 0 0 1 1 1 0 Pathogenicity factor MIP-T3 PF10243.4 CDI86445.1 - 5.8 5.2 21.3 6.8 5.0 14.8 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Claudin_2 PF13903.1 CDI86446.1 - 0.00087 19.0 15.6 0.023 14.3 3.3 2.5 2 0 0 2 2 2 2 PMP-22/EMP/MP20/Claudin tight junction SR-25 PF10500.4 CDI86446.1 - 0.18 11.2 23.8 0.078 12.4 13.3 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Sporozoite_P67 PF05642.6 CDI86446.1 - 0.19 9.5 8.8 0.24 9.2 6.1 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen SKIP_SNW PF02731.10 CDI86447.1 - 0.0015 18.0 3.7 0.0023 17.4 2.5 1.2 1 0 0 1 1 1 1 SKIP/SNW domain Ins145_P3_rec PF08709.6 CDI86449.1 - 0.034 13.1 0.0 5.8 5.8 0.0 2.2 2 0 0 2 2 2 0 Inositol 1,4,5-trisphosphate/ryanodine receptor AAA_2 PF07724.9 CDI86450.1 - 3e-27 95.6 0.1 4.7e-27 94.9 0.1 1.3 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) ClpB_D2-small PF10431.4 CDI86450.1 - 1.6e-14 53.5 0.0 2.8e-14 52.7 0.0 1.4 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.9 CDI86450.1 - 3.5e-05 23.5 0.0 0.00016 21.4 0.0 2.0 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Rtf2 PF04641.7 CDI86452.1 - 6.3 5.9 16.4 6.7 5.8 11.4 1.0 1 0 0 1 1 1 0 Rtf2 RING-finger DUF3464 PF11947.3 CDI86452.1 - 7 6.0 13.0 8.5 5.8 9.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) AIF_C PF14721.1 CDI86453.1 - 0.069 13.3 15.0 0.079 13.1 10.4 1.1 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term DAHP_synth_2 PF01474.11 CDI86453.1 - 0.091 11.1 12.7 0.1 10.9 8.8 1.0 1 0 0 1 1 1 0 Class-II DAHP synthetase family FimP PF09766.4 CDI86453.1 - 0.19 10.7 30.1 0.23 10.4 20.8 1.2 1 0 0 1 1 1 0 Fms-interacting protein Pex14_N PF04695.8 CDI86453.1 - 0.83 9.6 27.4 0.89 9.5 19.0 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF4175 PF13779.1 CDI86453.1 - 1.4 6.5 45.5 1.4 6.5 31.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) RIC3 PF15361.1 CDI86453.1 - 1.8 8.7 19.5 2 8.6 13.5 1.1 1 0 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 RNB PF00773.14 CDI86453.1 - 1.9 7.7 10.3 2 7.6 7.1 1.0 1 0 0 1 1 1 0 RNB domain Pox_Ag35 PF03286.9 CDI86453.1 - 2.4 7.6 15.3 2.7 7.4 10.6 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein PH_4 PF15404.1 CDI86453.1 - 2.4 7.6 13.9 3 7.3 9.7 1.3 1 0 0 1 1 1 0 Pleckstrin homology domain Peptidase_U57 PF05582.7 CDI86453.1 - 3.9 6.3 15.0 3.8 6.4 10.4 1.1 1 0 0 1 1 1 0 YabG peptidase U57 DUF4557 PF15101.1 CDI86453.1 - 4 7.2 32.9 4.8 6.9 22.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) LIM_bind PF01803.11 CDI86453.1 - 4.2 6.4 24.5 4.8 6.2 17.0 1.0 1 0 0 1 1 1 0 LIM-domain binding protein eIF3_subunit PF08597.5 CDI86453.1 - 4.2 6.8 27.2 4.5 6.7 18.9 1.0 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit Suf PF05843.9 CDI86453.1 - 4.7 6.8 27.8 5.8 6.5 19.3 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Rtf2 PF04641.7 CDI86453.1 - 5.4 6.1 25.0 5.9 6.0 17.3 1.0 1 0 0 1 1 1 0 Rtf2 RING-finger DUF1266 PF06889.6 CDI86453.1 - 5.6 6.7 11.6 6.3 6.5 8.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1266) Gti1_Pac2 PF09729.4 CDI86453.1 - 6.5 6.6 13.6 6.9 6.5 9.4 1.2 1 0 0 1 1 1 0 Gti1/Pac2 family EIIBC-GUT_N PF03612.9 CDI86453.1 - 6.6 6.3 15.4 8 6.0 10.6 1.3 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Lin-8 PF03353.10 CDI86453.1 - 6.7 5.8 25.7 7.9 5.6 17.8 1.0 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist PAT1 PF09770.4 CDI86453.1 - 7.3 4.6 44.0 8 4.5 30.5 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF4011 PF13195.1 CDI86453.1 - 7.9 6.4 12.4 11 5.9 8.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4011) Pal1 PF08316.6 CDI86453.1 - 8.4 6.8 11.5 9.9 6.6 8.0 1.2 1 0 0 1 1 1 0 Pal1 cell morphology protein DUF3866 PF12982.2 CDI86453.1 - 8.7 5.2 9.0 10 5.0 6.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3866) Baculo_PP31 PF05311.6 CDI86453.1 - 9.3 5.4 20.8 9.8 5.3 14.4 1.1 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) Dynamin_N PF00350.18 CDI86453.1 - 9.4 6.0 11.0 9.8 5.9 7.7 1.2 1 0 0 1 1 1 0 Dynamin family OATP PF03137.15 CDI86453.1 - 9.5 4.1 14.2 9.3 4.1 9.8 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Ctr PF04145.10 CDI86453.1 - 9.7 6.2 11.2 11 6.1 7.8 1.3 1 0 0 1 1 1 0 Ctr copper transporter family FAM60A PF15396.1 CDI86453.1 - 9.7 5.8 16.1 11 5.6 11.2 1.1 1 0 0 1 1 1 0 Protein Family FAM60A PPP4R2 PF09184.6 CDI86453.1 - 10 5.5 19.2 11 5.4 13.3 1.0 1 0 0 1 1 1 0 PPP4R2 CTC1 PF15489.1 CDI86454.1 - 2.5e-05 21.9 0.4 2.6e-05 21.8 0.3 1.1 1 0 0 1 1 1 1 CST, telomere maintenance, complex subunit CTC1 dsDNA_bind PF01984.15 CDI86454.1 - 0.024 14.5 9.9 0.058 13.3 6.9 1.7 1 0 0 1 1 1 0 Double-stranded DNA-binding domain DivIC PF04977.10 CDI86454.1 - 1.6 8.2 8.5 2.9 7.4 5.9 1.4 1 0 0 1 1 1 0 Septum formation initiator TFIIA PF03153.8 CDI86454.1 - 2.1 8.1 26.2 3.2 7.5 18.1 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Peptidase_S64 PF08192.6 CDI86454.1 - 2.7 6.2 8.7 3.4 5.8 6.0 1.2 1 0 0 1 1 1 0 Peptidase family S64 IER PF05760.7 CDI86454.1 - 3.9 7.3 21.5 5 6.9 14.9 1.1 1 0 0 1 1 1 0 Immediate early response protein (IER) PLRV_ORF5 PF01690.12 CDI86454.1 - 3.9 6.5 6.4 4.6 6.2 4.5 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein SNARE_assoc PF09335.6 CDI86455.1 - 1.1e-09 38.5 0.9 2.7e-09 37.2 0.0 2.0 2 1 0 2 2 2 1 SNARE associated Golgi protein SAGA-Tad1 PF12767.2 CDI86455.1 - 0.00012 21.8 6.8 0.00015 21.5 4.7 1.2 1 0 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit SR-25 PF10500.4 CDI86455.1 - 0.00013 21.5 23.0 0.00032 20.2 15.9 1.6 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein SOBP PF15279.1 CDI86455.1 - 0.00016 22.1 5.2 0.00018 22.0 3.6 1.2 1 0 0 1 1 1 1 Sine oculis-binding protein Spore_coat_CotO PF14153.1 CDI86455.1 - 0.0023 17.4 6.5 0.0034 16.8 4.5 1.3 1 0 0 1 1 1 1 Spore coat protein CotO Band_3_cyto PF07565.8 CDI86455.1 - 0.0075 15.8 2.9 0.0087 15.5 2.0 1.4 1 0 0 1 1 1 1 Band 3 cytoplasmic domain Sec62 PF03839.11 CDI86455.1 - 0.024 14.0 0.3 0.03 13.7 0.2 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 LMBR1 PF04791.11 CDI86455.1 - 0.038 12.5 1.0 0.045 12.3 0.7 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Suf PF05843.9 CDI86455.1 - 0.051 13.2 15.8 0.076 12.7 11.0 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Cwf_Cwc_15 PF04889.7 CDI86455.1 - 0.35 10.5 16.7 0.51 10.0 11.6 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein FimP PF09766.4 CDI86455.1 - 0.37 9.8 16.3 0.48 9.4 11.3 1.2 1 0 0 1 1 1 0 Fms-interacting protein Neur_chan_memb PF02932.11 CDI86455.1 - 0.59 9.9 3.9 0.83 9.4 2.7 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region CAF-1_p150 PF11600.3 CDI86455.1 - 0.62 9.3 25.6 1.1 8.5 17.8 1.3 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal MDFI PF15316.1 CDI86455.1 - 1 9.3 10.9 0.096 12.6 3.5 2.1 2 0 0 2 2 2 0 MyoD family inhibitor Peptidase_S64 PF08192.6 CDI86455.1 - 1.3 7.2 9.9 2 6.6 6.9 1.3 1 0 0 1 1 1 0 Peptidase family S64 APG6 PF04111.7 CDI86455.1 - 1.5 7.8 15.0 2.1 7.3 10.4 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF4614 PF15391.1 CDI86455.1 - 1.5 8.5 25.0 0.099 12.4 11.8 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4614) Gag_spuma PF03276.9 CDI86455.1 - 1.5 7.0 21.0 2.6 6.2 14.6 1.4 1 0 0 1 1 1 0 Spumavirus gag protein Raftlin PF15250.1 CDI86455.1 - 1.9 6.8 14.6 2.6 6.4 10.1 1.1 1 0 0 1 1 1 0 Raftlin NPR3 PF03666.8 CDI86455.1 - 2.3 6.6 13.6 3.1 6.2 9.4 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF4207 PF13904.1 CDI86455.1 - 2.8 7.2 32.2 5.5 6.2 22.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4207) AUX_IAA PF02309.11 CDI86455.1 - 3.2 7.4 13.9 4.9 6.8 9.7 1.2 1 0 0 1 1 1 0 AUX/IAA family RR_TM4-6 PF06459.7 CDI86455.1 - 4.2 7.1 14.9 7.9 6.2 10.3 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Vma12 PF11712.3 CDI86455.1 - 7.2 6.3 7.0 2 8.1 1.9 2.0 2 1 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase PAT1 PF09770.4 CDI86455.1 - 8 4.5 26.4 11 4.0 18.3 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 THRAP3_BCLAF1 PF15440.1 CDI86455.1 - 9.6 4.7 26.5 12 4.4 18.4 1.0 1 0 0 1 1 1 0 THRAP3/BCLAF1 family CAF-1_p150 PF11600.3 CDI86457.1 - 0.00036 19.9 25.0 0.0005 19.5 17.3 1.1 1 0 0 1 1 1 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal Band_7 PF01145.20 CDI86457.1 - 0.018 14.9 0.9 0.018 14.9 0.6 2.1 2 0 0 2 2 2 0 SPFH domain / Band 7 family SprA-related PF12118.3 CDI86457.1 - 0.021 14.1 44.1 0.024 13.9 30.5 1.0 1 0 0 1 1 1 0 SprA-related family Med15 PF09606.5 CDI86457.1 - 0.15 10.2 44.1 0.15 10.1 30.6 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal SOBP PF15279.1 CDI86457.1 - 1.6 9.0 27.5 1.8 8.9 19.1 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein PAT1 PF09770.4 CDI86457.1 - 1.9 6.6 39.5 1.9 6.6 27.3 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF4220 PF13968.1 CDI86457.1 - 5.4 6.0 14.1 6.5 5.7 9.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4220) Usp PF00582.21 CDI86457.1 - 8.1 6.6 6.6 6 7.0 0.3 2.1 1 1 1 2 2 2 0 Universal stress protein family DUF605 PF04652.11 CDI86457.1 - 8.4 5.6 35.8 9.2 5.5 24.8 1.0 1 0 0 1 1 1 0 Vta1 like CENP-C_mid PF15620.1 CDI86458.1 - 0.0027 17.4 6.8 0.0037 17.0 4.7 1.1 1 0 0 1 1 1 1 Centromere assembly component CENP-C middle DNMT3B-binding region Neur_chan_memb PF02932.11 CDI86458.1 - 0.28 11.0 3.8 0.42 10.4 2.6 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region SOBP PF15279.1 CDI86458.1 - 0.94 9.7 12.5 1.4 9.1 8.6 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein FCP1_C PF09309.5 CDI86458.1 - 5.9 6.1 16.7 5.8 6.1 0.9 2.6 2 0 0 2 2 2 0 FCP1, C-terminal PAT1 PF09770.4 CDI86458.1 - 6.6 4.8 38.1 8.1 4.5 26.4 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 FYDLN_acid PF09538.5 CDI86459.1 - 0.2 12.2 16.9 0.56 10.8 2.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) SOBP PF15279.1 CDI86459.1 - 0.37 11.1 21.2 0.47 10.7 14.7 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein Trypan_glycop_C PF10659.4 CDI86459.1 - 0.41 10.9 25.8 0.89 9.8 6.9 2.2 2 0 0 2 2 2 0 Trypanosome variant surface glycoprotein C-terminal domain CDC27 PF09507.5 CDI86459.1 - 0.92 8.6 31.9 1.1 8.4 22.1 1.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 FAM176 PF14851.1 CDI86459.1 - 0.99 9.0 19.0 2.1 7.9 5.0 2.1 2 0 0 2 2 2 0 FAM176 family Peptidase_S64 PF08192.6 CDI86459.1 - 1.3 7.2 22.0 1.5 7.0 15.3 1.0 1 0 0 1 1 1 0 Peptidase family S64 Nha1_C PF08619.5 CDI86459.1 - 1.3 8.2 26.6 1.6 7.9 18.4 1.1 1 0 0 1 1 1 0 Alkali metal cation/H+ antiporter Nha1 C terminus DUF3357 PF11837.3 CDI86459.1 - 1.3 8.8 9.1 0.38 10.6 0.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3357) LIM_bind PF01803.11 CDI86459.1 - 1.6 7.7 32.1 1.2 8.1 8.3 2.0 2 0 0 2 2 2 0 LIM-domain binding protein PBP1_TM PF14812.1 CDI86459.1 - 2.5 8.4 18.7 2.3 8.5 5.4 2.1 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal E7 PF00527.13 CDI86459.1 - 2.9 8.1 24.4 1.8 8.7 4.9 2.3 2 0 0 2 2 2 0 E7 protein, Early protein SspB PF04386.8 CDI86459.1 - 3.1 7.4 25.5 0.18 11.4 6.0 2.1 2 0 0 2 2 2 0 Stringent starvation protein B Draxin PF15550.1 CDI86459.1 - 3.1 7.3 28.0 3.9 7.0 19.4 1.1 1 0 0 1 1 1 0 Draxin YqfQ PF14181.1 CDI86459.1 - 3.1 7.8 31.5 5.4 7.0 8.5 2.2 2 0 0 2 2 2 0 YqfQ-like protein Pox_Ag35 PF03286.9 CDI86459.1 - 3.2 7.2 20.4 1.1 8.7 2.9 2.0 2 0 0 2 2 2 0 Pox virus Ag35 surface protein Eapp_C PF10238.4 CDI86459.1 - 3.6 7.4 23.3 0.54 10.1 4.1 2.1 2 0 0 2 2 2 0 E2F-associated phosphoprotein DUF2146 PF10220.4 CDI86459.1 - 4.1 5.2 22.0 5 4.9 15.2 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2146) Pap_E4 PF02711.9 CDI86459.1 - 5 8.0 24.2 9.2 7.1 6.6 2.1 2 0 0 2 2 2 0 E4 protein Herpes_UL87 PF03043.9 CDI86459.1 - 5 5.3 14.4 6.1 5.0 10.0 1.1 1 0 0 1 1 1 0 Herpesvirus UL87 family Hep_59 PF07052.6 CDI86459.1 - 5.6 7.3 25.6 2.7 8.4 6.2 2.3 2 0 0 2 2 2 0 Hepatocellular carcinoma-associated antigen 59 Exonuc_VII_L PF02601.10 CDI86459.1 - 7.3 5.6 29.4 9.2 5.3 20.4 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit PSK PF06404.7 CDI86459.1 - 7.5 7.3 23.6 5 7.9 7.4 2.3 2 0 0 2 2 2 0 Phytosulfokine precursor protein (PSK) Herpes_DNAp_acc PF04929.7 CDI86459.1 - 8.6 5.2 21.4 12 4.7 14.9 1.2 1 0 0 1 1 1 0 Herpes DNA replication accessory factor FAR1 PF03101.10 CDI86459.1 - 9.5 6.8 15.2 0.52 10.8 1.3 2.3 2 0 0 2 2 2 0 FAR1 DNA-binding domain Stig1 PF04885.8 CDI86459.1 - 9.6 6.4 15.3 7.3 6.7 3.7 2.1 2 0 0 2 2 2 0 Stigma-specific protein, Stig1 SR-25 PF10500.4 CDI86460.1 - 0.00047 19.7 28.6 0.00047 19.7 19.8 16.0 5 5 9 15 15 15 1 Nuclear RNA-splicing-associated protein Med15 PF09606.5 CDI86461.1 - 0.15 10.2 72.6 0.17 10.0 50.3 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal SprA-related PF12118.3 CDI86462.1 - 0.038 13.3 28.4 0.05 12.9 19.7 1.2 1 0 0 1 1 1 0 SprA-related family Suf PF05843.9 CDI86462.1 - 0.51 10.0 17.4 0.6 9.7 12.1 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Serinc PF03348.10 CDI86462.1 - 2.1 6.9 13.4 2.8 6.5 9.3 1.3 1 0 0 1 1 1 0 Serine incorporator (Serinc) DUF755 PF05501.6 CDI86463.1 - 0.029 14.4 18.0 0.029 14.4 12.5 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF755) RAP1 PF07218.6 CDI86463.1 - 2 6.3 10.2 2.4 6.1 7.1 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DUF4407 PF14362.1 CDI86463.1 - 3.5 6.5 14.1 4.9 6.0 9.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) APC_CDC26 PF10471.4 CDI86463.1 - 3.7 8.3 37.7 0.24 12.1 7.5 3.1 3 0 0 3 3 3 0 Anaphase-promoting complex APC subunit 1 Ndc1_Nup PF09531.5 CDI86463.1 - 5.1 5.3 13.3 5.7 5.2 9.2 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup MACPF PF01823.14 CDI86463.1 - 6 6.5 14.3 0.29 10.7 5.0 2.0 1 1 1 2 2 2 0 MAC/Perforin domain DNA_pol_viral_N PF00242.12 CDI86463.1 - 9 5.2 26.2 11 4.9 18.2 1.1 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain Activator_LAG-3 PF11498.3 CDI86464.1 - 0.00019 20.3 25.2 0.00024 19.9 17.5 1.2 1 0 0 1 1 1 1 Transcriptional activator LAG-3 Latrophilin PF02354.11 CDI86464.1 - 0.0012 17.6 2.9 0.0015 17.3 2.0 1.1 1 0 0 1 1 1 1 Latrophilin Cytoplasmic C-terminal region CDV3 PF15359.1 CDI86464.1 - 0.0062 16.6 3.0 0.0062 16.6 2.1 1.8 1 1 1 2 2 2 1 Carnitine deficiency-associated protein 3 Spt20 PF12090.3 CDI86464.1 - 0.022 14.1 5.1 0.032 13.5 3.5 1.3 1 0 0 1 1 1 0 Spt20 family PAT1 PF09770.4 CDI86464.1 - 0.034 12.4 28.2 0.038 12.2 19.5 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 LpxB PF02684.10 CDI86464.1 - 0.43 9.1 4.5 0.56 8.7 3.1 1.1 1 0 0 1 1 1 0 Lipid-A-disaccharide synthetase SOBP PF15279.1 CDI86464.1 - 0.51 10.6 10.8 0.6 10.4 7.5 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein UPF0560 PF10577.4 CDI86464.1 - 0.71 8.0 10.8 0.77 7.9 7.5 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Nuc_deoxyrib_tr PF05014.10 CDI86464.1 - 1.4 8.7 6.5 1.8 8.4 4.0 1.6 1 1 0 1 1 1 0 Nucleoside 2-deoxyribosyltransferase DUF2232 PF09991.4 CDI86464.1 - 2 7.3 4.2 3 6.7 2.9 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) Mcm10 PF09332.6 CDI86464.1 - 2.9 7.1 13.8 3.9 6.7 9.6 1.3 1 0 0 1 1 1 0 Mcm10 replication factor EIF4E-T PF10477.4 CDI86464.1 - 3.2 6.4 8.9 3.7 6.2 6.2 1.1 1 0 0 1 1 1 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E Peptidase_U57 PF05582.7 CDI86464.1 - 4.6 6.1 6.5 6.7 5.5 4.5 1.1 1 0 0 1 1 1 0 YabG peptidase U57 LCD1 PF09798.4 CDI86464.1 - 5.7 4.8 9.7 6.6 4.5 6.7 1.0 1 0 0 1 1 1 0 DNA damage checkpoint protein Serinc PF03348.10 CDI86464.1 - 6.7 5.3 6.5 9.2 4.8 4.5 1.3 1 0 0 1 1 1 0 Serine incorporator (Serinc) DUF3450 PF11932.3 CDI86466.1 - 1.3 8.2 7.0 1.6 7.9 4.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) MSP1_C PF07462.6 CDI86467.1 - 2.7 6.2 21.5 3 6.1 14.9 1.2 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Glutenin_hmw PF03157.8 CDI86468.1 - 0.31 9.2 11.7 0.5 8.5 8.1 1.3 1 0 0 1 1 1 0 High molecular weight glutenin subunit TerD PF02342.13 CDI86469.1 - 3.5e-12 46.0 0.0 2.1e-11 43.5 0.0 2.1 1 1 0 1 1 1 1 TerD domain PhoD PF09423.5 CDI86470.1 - 1.4e-09 37.0 0.0 3e-09 35.9 0.0 1.5 1 1 0 1 1 1 1 PhoD-like phosphatase P12 PF12669.2 CDI86470.1 - 0.19 11.9 1.8 0.55 10.4 1.2 1.7 1 0 0 1 1 1 0 Virus attachment protein p12 family COX4 PF02936.9 CDI86471.1 - 0.0011 18.7 0.0 0.0013 18.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV PWI PF01480.12 CDI86472.1 - 2.3e-28 98.0 0.0 3.2e-28 97.6 0.0 1.2 1 0 0 1 1 1 1 PWI domain PYC_OADA PF02436.13 CDI86472.1 - 0.088 12.2 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Conserved carboxylase domain eIF3_p135 PF12807.2 CDI86473.1 - 9.4e-10 38.6 0.1 3.5e-09 36.8 0.0 2.0 2 0 0 2 2 2 1 Translation initiation factor eIF3 subunit 135 TPR_12 PF13424.1 CDI86473.1 - 6.2e-05 22.8 2.5 0.025 14.5 0.2 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat Apc3 PF12895.2 CDI86473.1 - 0.018 15.1 0.8 0.22 11.6 0.2 2.9 2 1 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 DUF3228 PF11539.3 CDI86474.1 - 6.3e-79 263.6 0.0 7.4e-79 263.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3228) Ribosomal_L22e PF01776.12 CDI86475.1 - 1.5e-44 150.5 1.7 1.8e-44 150.2 1.2 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family DUF288 PF03385.12 CDI86475.1 - 0.11 10.9 0.1 0.12 10.8 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function, DUF288 DEAD PF00270.24 CDI86477.1 - 3.5e-36 124.2 0.0 9e-36 122.8 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CDI86477.1 - 5e-25 87.1 0.0 6.2e-12 45.2 0.0 2.6 1 1 1 2 2 2 2 Helicase conserved C-terminal domain DSPc PF00782.15 CDI86477.1 - 6.4e-10 38.7 0.0 1.2e-09 37.8 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 CDI86477.1 - 0.097 11.9 0.1 0.17 11.1 0.1 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Oxysterol_BP PF01237.13 CDI86477.1 - 0.41 9.0 3.2 0.63 8.4 2.2 1.2 1 0 0 1 1 1 0 Oxysterol-binding protein DSS1_SEM1 PF05160.8 CDI86478.1 - 0.00011 21.9 20.8 0.0039 16.9 14.4 2.3 1 1 0 1 1 1 1 DSS1/SEM1 family Rotamase_2 PF13145.1 CDI86478.1 - 0.063 13.9 4.0 0.27 11.8 2.8 1.9 1 1 0 1 1 1 0 PPIC-type PPIASE domain Cwf_Cwc_15 PF04889.7 CDI86478.1 - 0.13 11.9 5.0 0.15 11.7 3.4 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein SDA1 PF05285.7 CDI86478.1 - 3.9 6.6 7.0 4.4 6.5 4.9 1.0 1 0 0 1 1 1 0 SDA1 AIF_C PF14721.1 CDI86480.1 - 0.17 12.1 14.7 0.18 12.0 10.2 1.0 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Spore_coat_CotO PF14153.1 CDI86480.1 - 4.2 6.7 25.4 4.3 6.7 17.6 1.0 1 0 0 1 1 1 0 Spore coat protein CotO Rtf2 PF04641.7 CDI86480.1 - 4.2 6.4 16.3 4.9 6.2 11.3 1.0 1 0 0 1 1 1 0 Rtf2 RING-finger MRI PF15325.1 CDI86480.1 - 4.3 8.3 6.5 4.9 8.1 4.5 1.1 1 0 0 1 1 1 0 Modulator of retrovirus infection FimP PF09766.4 CDI86480.1 - 4.4 6.2 30.7 5.7 5.9 21.3 1.2 1 0 0 1 1 1 0 Fms-interacting protein PBP1_TM PF14812.1 CDI86480.1 - 4.9 7.5 10.4 6.2 7.2 7.2 1.2 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Pex14_N PF04695.8 CDI86480.1 - 5.2 7.1 27.8 6 6.9 19.3 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF2058 PF09831.4 CDI86480.1 - 5.3 6.8 28.2 5.6 6.8 19.6 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2058) DUF3043 PF11241.3 CDI86480.1 - 5.9 6.4 13.4 7.8 6.0 9.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) FYDLN_acid PF09538.5 CDI86480.1 - 6 7.4 8.8 7.1 7.2 6.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) YqfQ PF14181.1 CDI86480.1 - 6.2 6.8 20.6 6.8 6.6 14.3 1.0 1 0 0 1 1 1 0 YqfQ-like protein DUF1764 PF08576.5 CDI86480.1 - 6.3 7.6 18.5 7.4 7.4 12.8 1.2 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) DUF2201_N PF13203.1 CDI86480.1 - 6.5 5.8 21.0 6.8 5.7 14.6 1.0 1 0 0 1 1 1 0 Putative metallopeptidase domain CDC45 PF02724.9 CDI86480.1 - 7.2 4.5 17.9 7.5 4.4 12.4 1.0 1 0 0 1 1 1 0 CDC45-like protein GOLD_2 PF13897.1 CDI86480.1 - 7.5 6.7 9.3 8 6.6 6.5 1.1 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking Paf1 PF03985.8 CDI86480.1 - 7.6 5.1 23.0 7.6 5.1 16.0 1.0 1 0 0 1 1 1 0 Paf1 Dala_Dala_lig_N PF01820.16 CDI86480.1 - 8 6.8 10.1 9 6.6 7.0 1.2 1 0 0 1 1 1 0 D-ala D-ala ligase N-terminus Bud13 PF09736.4 CDI86480.1 - 8.3 6.6 24.1 8.4 6.6 16.7 1.0 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex Sox_N PF12444.3 CDI86480.1 - 8.3 7.5 11.7 9.6 7.3 8.1 1.1 1 0 0 1 1 1 0 Sox developmental protein N terminal RR_TM4-6 PF06459.7 CDI86480.1 - 9.1 6.0 18.4 9 6.0 12.7 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 PH_4 PF15404.1 CDI86480.1 - 9.2 5.7 15.0 12 5.3 10.4 1.2 1 0 0 1 1 1 0 Pleckstrin homology domain DUF3984 PF13136.1 CDI86480.1 - 9.2 5.3 19.7 8.9 5.4 13.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3984) RskA PF10099.4 CDI86481.1 - 0.0023 17.7 11.9 0.0023 17.7 8.3 2.7 2 1 0 2 2 2 1 Anti-sigma-K factor rskA FA_desaturase PF00487.19 CDI86481.1 - 0.0049 16.3 0.3 0.014 14.8 0.0 1.7 2 0 0 2 2 2 1 Fatty acid desaturase Spt20 PF12090.3 CDI86481.1 - 0.051 12.9 13.9 0.087 12.1 0.7 2.2 2 0 0 2 2 2 0 Spt20 family DUF1469 PF07332.6 CDI86481.1 - 0.48 10.1 16.6 1.5 8.5 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1469) DUF2371 PF10177.4 CDI86481.1 - 2.9 7.7 5.3 8.5 6.2 2.4 2.2 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2371) BCD PF15461.1 CDI86481.1 - 5.1 6.4 8.2 3 7.1 0.3 2.1 2 0 0 2 2 2 0 Beta-carotene 15,15'-dioxygenase DUF1180 PF06679.7 CDI86481.1 - 6.2 6.6 12.4 7.6 6.4 2.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) UPF0565 PF10561.4 CDI86481.1 - 6.2 5.6 10.5 3.2 6.5 5.1 1.9 2 0 0 2 2 2 0 Uncharacterised protein family UPF0565 DUF4175 PF13779.1 CDI86482.1 - 0.00012 20.0 42.1 0.00016 19.5 29.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4175) Ycf1 PF05758.7 CDI86482.1 - 0.0031 15.3 9.7 0.0036 15.1 6.7 1.1 1 0 0 1 1 1 1 Ycf1 Spore_coat_CotO PF14153.1 CDI86482.1 - 0.0041 16.5 23.8 0.0041 16.5 16.5 1.8 2 0 0 2 2 2 1 Spore coat protein CotO Band_3_cyto PF07565.8 CDI86482.1 - 0.051 13.0 13.4 0.1 12.1 9.3 1.6 1 0 0 1 1 1 0 Band 3 cytoplasmic domain CDC45 PF02724.9 CDI86482.1 - 0.15 10.0 14.8 0.24 9.4 10.3 1.3 1 0 0 1 1 1 0 CDC45-like protein Hid1 PF12722.2 CDI86482.1 - 0.2 9.2 16.2 0.26 8.9 11.2 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Suf PF05843.9 CDI86482.1 - 0.55 9.9 25.2 1.1 8.8 17.4 1.5 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) PAT1 PF09770.4 CDI86482.1 - 0.82 7.8 56.8 0.0078 14.5 34.1 1.4 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 Herpes_env PF01673.13 CDI86482.1 - 1.8 7.0 16.5 2.9 6.3 11.4 1.2 1 0 0 1 1 1 0 Herpesvirus putative major envelope glycoprotein Zip PF02535.17 CDI86482.1 - 2.4 7.0 5.5 3.9 6.4 3.8 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter HCO3_cotransp PF00955.16 CDI86482.1 - 2.4 6.7 6.2 3.4 6.2 4.3 1.1 1 0 0 1 1 1 0 HCO3- transporter family Presenilin PF01080.12 CDI86482.1 - 2.5 6.8 9.4 4.1 6.1 6.5 1.3 1 0 0 1 1 1 0 Presenilin Ndc1_Nup PF09531.5 CDI86482.1 - 3 6.1 15.2 4.2 5.6 10.6 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup YjgP_YjgQ PF03739.9 CDI86482.1 - 3.4 6.2 6.3 5.7 5.5 4.4 1.4 1 0 0 1 1 1 0 Predicted permease YjgP/YjgQ family V_ATPase_I PF01496.14 CDI86482.1 - 5.8 4.6 13.3 9.8 3.8 9.2 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Draxin PF15550.1 CDI86483.1 - 5.5 6.5 25.8 6.4 6.3 17.9 1.1 1 0 0 1 1 1 0 Draxin Utp14 PF04615.8 CDI86483.1 - 7.7 4.5 40.6 8.2 4.4 28.1 1.0 1 0 0 1 1 1 0 Utp14 protein DUF1510 PF07423.6 CDI86483.1 - 8.5 5.6 40.1 10 5.3 27.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DUF1635 PF07795.6 CDI86484.1 - 0.0028 17.0 2.6 0.0033 16.8 1.8 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1635) DUF389 PF04087.9 CDI86484.1 - 0.0075 16.2 2.1 0.15 12.0 2.1 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF389) Velvet PF11754.3 CDI86484.1 - 0.046 13.3 2.3 0.052 13.1 1.6 1.2 1 0 0 1 1 1 0 Velvet factor RskA PF10099.4 CDI86484.1 - 0.069 12.8 17.1 0.74 9.5 7.4 2.1 2 0 0 2 2 2 0 Anti-sigma-K factor rskA MARCKS PF02063.12 CDI86484.1 - 0.11 12.3 21.4 0.14 11.9 14.8 1.2 1 0 0 1 1 1 0 MARCKS family DUF966 PF06136.8 CDI86484.1 - 0.12 11.7 9.8 0.15 11.4 6.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) APC_CDC26 PF10471.4 CDI86484.1 - 0.46 11.2 22.0 0.94 10.2 8.4 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit 1 DUF3399 PF11879.3 CDI86484.1 - 0.83 9.9 12.1 1.8 8.8 7.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3399) Suf PF05843.9 CDI86484.1 - 1.8 8.2 6.4 2.3 7.8 4.4 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF572 PF04502.8 CDI86484.1 - 2.4 7.3 13.1 3.7 6.6 9.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) MRI PF15325.1 CDI86484.1 - 2.6 9.0 9.5 0.28 12.1 0.8 2.4 1 1 1 2 2 2 0 Modulator of retrovirus infection MRP-S31 PF15433.1 CDI86484.1 - 2.8 7.2 12.3 3.5 6.9 8.6 1.1 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 Conotoxin PF02950.12 CDI86484.1 - 3.6 8.4 11.6 0.089 13.5 1.6 2.5 2 1 0 2 2 2 0 Conotoxin TFIIA PF03153.8 CDI86484.1 - 3.9 7.2 16.3 5.3 6.8 11.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Pex14_N PF04695.8 CDI86484.1 - 4 7.4 14.3 1.8 8.6 6.1 2.1 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region BRF1 PF07741.8 CDI86484.1 - 9.3 6.5 13.6 2.6 8.3 1.2 2.3 2 0 0 2 2 2 0 Brf1-like TBP-binding domain Shadoo PF14999.1 CDI86485.1 - 0.16 11.8 7.7 0.23 11.3 5.3 1.2 1 0 0 1 1 1 0 Shadow of prion protein, neuroprotective SAGA-Tad1 PF12767.2 CDI86485.1 - 0.2 11.2 21.0 0.27 10.8 14.6 1.3 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit Init_tRNA_PT PF04179.7 CDI86485.1 - 0.34 9.7 10.8 0.34 9.7 7.5 1.1 1 0 0 1 1 1 0 Initiator tRNA phosphoribosyl transferase Ribosomal_60s PF00428.14 CDI86485.1 - 0.62 10.4 12.3 1.2 9.6 8.6 1.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein DUF243 PF03103.12 CDI86485.1 - 1.6 8.8 26.0 0.55 10.3 14.7 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF243) UPRTase PF14681.1 CDI86485.1 - 1.6 7.8 11.6 2.8 7.0 8.1 1.5 1 1 0 1 1 1 0 Uracil phosphoribosyltransferase RNA_pol_Rpb1_5 PF04998.12 CDI86485.1 - 2.9 7.0 7.7 3.2 6.9 5.3 1.2 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 AUX_IAA PF02309.11 CDI86485.1 - 4.9 6.8 14.2 6.7 6.3 9.9 1.3 1 0 0 1 1 1 0 AUX/IAA family BPL_N PF09825.4 CDI86485.1 - 9.9 4.8 8.7 11 4.6 6.0 1.1 1 0 0 1 1 1 0 Biotin-protein ligase, N terminal Phostensin_N PF13916.1 CDI86489.1 - 2.3 8.2 12.3 6.9 6.7 0.2 3.3 3 0 0 3 3 3 0 PP1-regulatory protein, Phostensin N-terminal Shadoo PF14999.1 CDI86490.1 - 0.0091 15.8 15.9 0.21 11.4 0.5 2.3 1 1 1 2 2 2 2 Shadow of prion protein, neuroprotective MIP-T3 PF10243.4 CDI86490.1 - 0.084 11.3 14.7 0.1 11.0 10.2 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DUF1183 PF06682.7 CDI86490.1 - 0.53 9.8 19.5 0.85 9.1 13.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) SpoVR PF04293.8 CDI86490.1 - 2.1 6.6 5.6 0.53 8.6 1.8 1.5 1 1 0 1 1 1 0 SpoVR like protein PHD_3 PF13922.1 CDI86490.1 - 2.5 8.4 23.9 1.1 9.5 4.2 3.0 3 0 0 3 3 3 0 PHD domain of transcriptional enhancer, Asx eIF-3_zeta PF05091.7 CDI86490.1 - 4.4 5.8 14.3 6.1 5.3 9.9 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Dicty_REP PF05086.7 CDI86490.1 - 7.4 4.1 10.4 9 3.9 7.2 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein RNF111_N PF15303.1 CDI86492.1 - 0.00072 19.1 7.1 0.00091 18.8 4.9 1.1 1 0 0 1 1 1 1 E3 ubiquitin-protein ligase Arkadia N-terminus PPDFL PF15060.1 CDI86492.1 - 0.035 14.1 2.6 0.051 13.5 1.8 1.2 1 0 0 1 1 1 0 Differentiation and proliferation regulator ERK-JNK_inhib PF15002.1 CDI86492.1 - 0.064 12.6 5.8 0.072 12.4 4.0 1.1 1 0 0 1 1 1 0 ERK and JNK pathways, inhibitor DUF3449 PF11931.3 CDI86492.1 - 0.14 11.6 5.8 0.16 11.4 4.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3449) DUF3801 PF12687.2 CDI86492.1 - 0.27 10.7 8.4 0.32 10.5 5.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3801) Reo_P9 PF06043.6 CDI86492.1 - 0.35 9.8 1.8 0.44 9.5 1.2 1.1 1 0 0 1 1 1 0 Reovirus P9-like family SprA-related PF12118.3 CDI86492.1 - 0.39 10.0 19.1 0.51 9.6 13.2 1.1 1 0 0 1 1 1 0 SprA-related family Med5 PF08689.5 CDI86492.1 - 0.42 8.2 6.2 0.48 8.0 4.3 1.0 1 0 0 1 1 1 0 Mediator complex subunit Med5 RR_TM4-6 PF06459.7 CDI86492.1 - 0.81 9.5 6.6 0.93 9.3 4.6 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Suf PF05843.9 CDI86492.1 - 0.89 9.2 9.3 1 9.0 6.5 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) SR-25 PF10500.4 CDI86492.1 - 0.93 8.9 22.1 1.7 8.0 15.4 1.4 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein LZ_Tnp_IS66 PF13007.2 CDI86492.1 - 1.4 9.6 13.4 14 6.3 9.2 2.2 1 1 0 1 1 1 0 Transposase C of IS166 homeodomain DUF2265 PF10023.4 CDI86492.1 - 1.4 7.9 9.1 1.8 7.6 6.3 1.1 1 0 0 1 1 1 0 Predicted aminopeptidase (DUF2265) Activator_LAG-3 PF11498.3 CDI86492.1 - 2 7.1 22.3 2.4 6.7 15.5 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 HAUS6_N PF14661.1 CDI86492.1 - 2.3 7.4 11.6 2.6 7.3 8.0 1.0 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Peptidase_S64 PF08192.6 CDI86492.1 - 2.4 6.3 7.3 2.8 6.1 5.1 1.0 1 0 0 1 1 1 0 Peptidase family S64 DUF4228 PF14009.1 CDI86492.1 - 2.5 8.2 9.6 2.6 8.1 6.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4228) AAA_23 PF13476.1 CDI86492.1 - 2.7 8.2 9.4 3.1 8.0 6.5 1.1 1 0 0 1 1 1 0 AAA domain DRY_EERY PF09750.4 CDI86492.1 - 5.9 7.0 12.6 34 4.5 8.7 1.8 1 1 0 1 1 1 0 Alternative splicing regulator MADF_DNA_bdg PF10545.4 CDI86492.1 - 6.4 7.0 8.2 11 6.3 5.7 1.4 1 1 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like BaxI_1 PF12811.2 CDI86492.1 - 8.3 5.4 6.4 11 5.1 4.4 1.2 1 0 0 1 1 1 0 Bax inhibitor 1 like Presenilin PF01080.12 CDI86492.1 - 9.1 4.9 7.5 11 4.7 5.2 1.1 1 0 0 1 1 1 0 Presenilin ProRS-C_1 PF09180.6 CDI86493.1 - 1.6e-28 98.3 0.0 2.8e-28 97.6 0.0 1.4 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal AP2 PF00847.15 CDI86494.1 - 9.7e-05 22.4 2.0 0.016 15.3 0.5 2.5 2 0 0 2 2 2 2 AP2 domain PH_4 PF15404.1 CDI86495.1 - 0.02 14.4 3.7 0.023 14.2 2.6 1.1 1 0 0 1 1 1 0 Pleckstrin homology domain FAM176 PF14851.1 CDI86495.1 - 0.2 11.2 2.7 0.26 10.9 1.8 1.1 1 0 0 1 1 1 0 FAM176 family DUF4381 PF14316.1 CDI86495.1 - 0.31 11.1 10.9 0.4 10.7 7.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) PAT1 PF09770.4 CDI86495.1 - 0.57 8.3 27.2 0.65 8.1 18.8 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TMEM51 PF15345.1 CDI86495.1 - 0.84 9.2 12.3 1.1 8.8 8.5 1.1 1 0 0 1 1 1 0 Transmembrane protein 51 Gag_spuma PF03276.9 CDI86495.1 - 1.5 7.0 16.4 1.5 7.0 11.4 1.0 1 0 0 1 1 1 0 Spumavirus gag protein SID-1_RNA_chan PF13965.1 CDI86495.1 - 1.6 6.7 4.7 1.8 6.6 3.2 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Folate_carrier PF01770.13 CDI86495.1 - 2.5 6.5 5.9 3 6.2 4.1 1.1 1 0 0 1 1 1 0 Reduced folate carrier OSTbeta PF15048.1 CDI86495.1 - 2.8 8.0 11.7 3.3 7.8 8.1 1.1 1 0 0 1 1 1 0 Organic solute transporter subunit beta protein CemA PF03040.9 CDI86495.1 - 3 7.3 11.1 3.1 7.3 7.7 1.0 1 0 0 1 1 1 0 CemA family Membralin PF09746.4 CDI86495.1 - 3 6.7 5.0 3.1 6.7 3.4 1.1 1 0 0 1 1 1 0 Tumour-associated protein Serinc PF03348.10 CDI86495.1 - 6.2 5.4 6.8 7.4 5.1 4.7 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) ALG3 PF05208.8 CDI86495.1 - 6.8 5.8 5.7 7.1 5.7 4.0 1.1 1 0 0 1 1 1 0 ALG3 protein Skp1 PF01466.14 CDI86498.1 - 3.3e-10 39.8 0.5 7.3e-09 35.5 0.1 2.2 2 0 0 2 2 2 1 Skp1 family, dimerisation domain DUF755 PF05501.6 CDI86498.1 - 0.028 14.4 3.3 0.031 14.3 2.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF755) Ribosomal_60s PF00428.14 CDI86498.1 - 0.1 13.0 7.4 0.13 12.7 5.1 1.2 1 0 0 1 1 1 0 60s Acidic ribosomal protein BAF1_ABF1 PF04684.8 CDI86498.1 - 0.16 10.8 3.0 0.17 10.6 2.1 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor AF-4 PF05110.8 CDI86498.1 - 0.28 9.0 8.6 0.3 8.8 6.0 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Macoilin PF09726.4 CDI86498.1 - 0.49 8.6 4.1 0.52 8.5 2.8 1.0 1 0 0 1 1 1 0 Transmembrane protein Pex14_N PF04695.8 CDI86499.1 - 0.013 15.5 16.4 0.014 15.4 11.3 1.0 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF4366 PF14283.1 CDI86499.1 - 0.016 14.6 1.9 0.016 14.6 1.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) RIC3 PF15361.1 CDI86499.1 - 0.019 15.1 9.4 0.022 14.9 6.5 1.0 1 0 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 Frizzled PF01534.12 CDI86499.1 - 0.081 11.6 0.9 0.094 11.4 0.6 1.0 1 0 0 1 1 1 0 Frizzled/Smoothened family membrane region PH_4 PF15404.1 CDI86499.1 - 0.16 11.4 11.7 0.19 11.2 8.1 1.0 1 0 0 1 1 1 0 Pleckstrin homology domain PP2C_2 PF13672.1 CDI86499.1 - 0.16 11.3 5.7 0.17 11.2 4.0 1.0 1 0 0 1 1 1 0 Protein phosphatase 2C DUF1764 PF08576.5 CDI86499.1 - 0.18 12.6 12.3 0.18 12.5 8.5 1.1 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) Peroxin-13_N PF04088.8 CDI86499.1 - 0.22 11.4 5.8 0.26 11.2 4.0 1.1 1 0 0 1 1 1 0 Peroxin 13, N-terminal region Peptidase_S49_N PF08496.5 CDI86499.1 - 0.24 11.2 10.0 0.26 11.0 6.9 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF3464 PF11947.3 CDI86499.1 - 0.26 10.7 8.1 0.29 10.5 5.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) ATAD4 PF15321.1 CDI86499.1 - 0.26 12.2 10.4 0.32 12.0 7.2 1.1 1 0 0 1 1 1 0 ATPase family AAA domain containing 4 GAGA_bind PF06217.7 CDI86499.1 - 0.3 11.0 8.6 0.29 11.0 6.0 1.0 1 0 0 1 1 1 0 GAGA binding protein-like family G-alpha PF00503.15 CDI86499.1 - 0.34 9.5 10.4 0.35 9.5 7.2 1.0 1 0 0 1 1 1 0 G-protein alpha subunit Zip PF02535.17 CDI86499.1 - 0.37 9.7 5.7 0.38 9.7 3.9 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter G-7-MTase PF12803.2 CDI86499.1 - 0.39 9.8 4.8 0.46 9.5 3.3 1.1 1 0 0 1 1 1 0 mRNA (guanine-7-)methyltransferase (G-7-MTase) EIIBC-GUT_N PF03612.9 CDI86499.1 - 0.67 9.5 9.4 0.78 9.3 6.5 1.1 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus DUF4355 PF14265.1 CDI86499.1 - 0.78 9.7 15.8 0.86 9.5 11.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4355) Gti1_Pac2 PF09729.4 CDI86499.1 - 0.79 9.5 8.6 0.78 9.5 5.9 1.0 1 0 0 1 1 1 0 Gti1/Pac2 family TraH_2 PF06871.6 CDI86499.1 - 0.96 8.8 5.0 0.94 8.8 3.4 1.0 1 0 0 1 1 1 0 TraH_2 Pal1 PF08316.6 CDI86499.1 - 1 9.8 5.1 0.99 9.8 3.6 1.1 1 0 0 1 1 1 0 Pal1 cell morphology protein Spc24 PF08286.6 CDI86499.1 - 1.1 9.0 11.6 1.1 8.9 8.1 1.0 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 Dala_Dala_lig_N PF01820.16 CDI86499.1 - 1.1 9.5 5.7 1.3 9.3 3.9 1.1 1 0 0 1 1 1 0 D-ala D-ala ligase N-terminus FAM176 PF14851.1 CDI86499.1 - 1.1 8.8 8.1 1.3 8.6 5.6 1.1 1 0 0 1 1 1 0 FAM176 family MRP-S26 PF14943.1 CDI86499.1 - 1.2 8.7 17.6 1.2 8.6 12.2 1.0 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 MSA-2c PF12238.3 CDI86499.1 - 1.2 8.7 8.2 1.2 8.7 5.7 1.0 1 0 0 1 1 1 0 Merozoite surface antigen 2c OATP PF03137.15 CDI86499.1 - 1.3 7.0 12.1 1.3 6.9 8.4 1.0 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family DUF912 PF06024.7 CDI86499.1 - 1.4 8.9 9.1 1.9 8.5 6.3 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Glyco_transf_15 PF01793.11 CDI86499.1 - 1.7 7.5 12.5 1.8 7.4 8.7 1.0 1 0 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase Packaging_FI PF14000.1 CDI86499.1 - 1.8 8.7 8.3 1.9 8.6 5.7 1.1 1 0 0 1 1 1 0 DNA packaging protein FI DUF2072 PF09845.4 CDI86499.1 - 2.1 8.2 5.8 2.2 8.2 4.1 1.1 1 0 0 1 1 1 0 Zn-ribbon containing protein (DUF2072) PBP1_TM PF14812.1 CDI86499.1 - 2.3 8.5 7.5 2.6 8.4 5.2 1.1 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal FemAB PF02388.11 CDI86499.1 - 2.3 6.7 12.6 2.3 6.8 8.8 1.0 1 0 0 1 1 1 0 FemAB family Peptidase_U57 PF05582.7 CDI86499.1 - 2.6 6.9 11.1 2.7 6.8 7.7 1.0 1 0 0 1 1 1 0 YabG peptidase U57 Dynamin_N PF00350.18 CDI86499.1 - 2.6 7.8 6.6 2.7 7.7 4.6 1.0 1 0 0 1 1 1 0 Dynamin family Na_trans_assoc PF06512.8 CDI86499.1 - 2.7 7.9 8.6 2.6 7.9 5.9 1.0 1 0 0 1 1 1 0 Sodium ion transport-associated DUF3708 PF12501.3 CDI86499.1 - 3 7.6 5.2 3.2 7.5 3.6 1.0 1 0 0 1 1 1 0 Phosphate ATP-binding cassette transporter Dehydrin PF00257.14 CDI86499.1 - 3.5 7.9 14.2 4.6 7.5 9.8 1.2 1 0 0 1 1 1 0 Dehydrin DUF2203 PF09969.4 CDI86499.1 - 3.7 7.8 8.7 3.7 7.7 6.1 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) FimP PF09766.4 CDI86499.1 - 3.7 6.5 27.5 4 6.4 19.1 1.0 1 0 0 1 1 1 0 Fms-interacting protein BRF1 PF07741.8 CDI86499.1 - 3.8 7.7 13.8 4.4 7.5 9.6 1.1 1 0 0 1 1 1 0 Brf1-like TBP-binding domain DUF1266 PF06889.6 CDI86499.1 - 3.9 7.2 9.3 3.9 7.2 6.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1266) DUF4175 PF13779.1 CDI86499.1 - 4 5.0 40.3 4.2 4.9 27.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) TraV PF09676.5 CDI86499.1 - 4 8.1 10.8 4.5 8.0 7.5 1.0 1 0 0 1 1 1 0 Type IV conjugative transfer system lipoprotein (TraV) LIM_bind PF01803.11 CDI86499.1 - 4.2 6.4 14.5 3.9 6.5 10.0 1.0 1 0 0 1 1 1 0 LIM-domain binding protein CD20 PF04103.10 CDI86499.1 - 4.2 7.2 6.3 4.7 7.1 4.4 1.2 1 0 0 1 1 1 0 CD20-like family Ctr PF04145.10 CDI86499.1 - 4.4 7.3 10.0 5.1 7.1 6.9 1.1 1 0 0 1 1 1 0 Ctr copper transporter family SelP_N PF04592.9 CDI86499.1 - 4.4 6.6 13.9 4.7 6.5 9.7 1.0 1 0 0 1 1 1 0 Selenoprotein P, N terminal region FAM60A PF15396.1 CDI86499.1 - 4.4 6.9 10.2 4.7 6.9 7.1 1.0 1 0 0 1 1 1 0 Protein Family FAM60A Folate_carrier PF01770.13 CDI86499.1 - 4.5 5.6 9.3 4.9 5.5 6.5 1.0 1 0 0 1 1 1 0 Reduced folate carrier Spc7_N PF15402.1 CDI86499.1 - 4.7 5.0 16.6 4.7 5.0 11.5 1.0 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 DUF3306 PF11748.3 CDI86499.1 - 4.9 7.8 12.6 5.6 7.6 8.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3306) RED_N PF07808.8 CDI86499.1 - 5.4 6.1 21.5 5.7 6.0 14.9 1.0 1 0 0 1 1 1 0 RED-like protein N-terminal region DHHW PF14286.1 CDI86499.1 - 5.4 6.2 9.1 5.3 6.2 6.3 1.0 1 0 0 1 1 1 0 DHHW protein DUF4199 PF13858.1 CDI86499.1 - 5.5 6.8 8.0 5.9 6.7 5.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) DUF2828 PF11443.3 CDI86499.1 - 6.2 4.8 10.8 6.4 4.8 7.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) tRNA-synt_2c PF01411.14 CDI86499.1 - 6.3 4.9 9.1 6.5 4.9 6.3 1.0 1 0 0 1 1 1 0 tRNA synthetases class II (A) BNR_3 PF13859.1 CDI86499.1 - 6.3 5.7 8.2 7.2 5.5 5.7 1.0 1 0 0 1 1 1 0 BNR repeat-like domain Kei1 PF08552.6 CDI86499.1 - 6.4 6.3 10.9 6.7 6.3 7.6 1.0 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 TMEM51 PF15345.1 CDI86499.1 - 6.5 6.3 16.7 7.3 6.2 11.5 1.2 1 0 0 1 1 1 0 Transmembrane protein 51 DDHD PF02862.12 CDI86499.1 - 6.6 6.4 13.4 6.9 6.4 9.3 1.0 1 0 0 1 1 1 0 DDHD domain SAGA-Tad1 PF12767.2 CDI86499.1 - 6.7 6.2 17.1 6.5 6.3 11.9 1.0 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit AIF_C PF14721.1 CDI86499.1 - 6.9 6.9 12.3 7.5 6.8 8.5 1.1 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term SeqA PF03925.8 CDI86499.1 - 6.9 6.3 13.2 7 6.2 9.1 1.0 1 0 0 1 1 1 0 SeqA protein Raftlin PF15250.1 CDI86499.1 - 7.2 5.0 13.2 7.4 4.9 9.2 1.0 1 0 0 1 1 1 0 Raftlin CKAP2_C PF15297.1 CDI86499.1 - 7.2 5.3 14.6 7.7 5.2 10.1 1.0 1 0 0 1 1 1 0 Cytoskeleton-associated protein 2 C-terminus DUF2201_N PF13203.1 CDI86499.1 - 7.2 5.6 14.7 7.3 5.6 10.2 1.0 1 0 0 1 1 1 0 Putative metallopeptidase domain Glt_symporter PF03616.9 CDI86499.1 - 7.7 4.9 6.1 8.1 4.8 4.2 1.1 1 0 0 1 1 1 0 Sodium/glutamate symporter DUF3043 PF11241.3 CDI86499.1 - 7.8 6.0 11.5 9.7 5.7 7.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) Plasmodium_Vir PF05795.6 CDI86499.1 - 7.9 5.5 6.3 8.2 5.5 4.4 1.0 1 0 0 1 1 1 0 Plasmodium vivax Vir protein GOLD_2 PF13897.1 CDI86499.1 - 8.2 6.6 6.1 8.5 6.6 4.2 1.1 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking Trypan_glycop_C PF10659.4 CDI86499.1 - 9 6.6 11.5 12 6.2 8.0 1.3 1 0 0 1 1 1 0 Trypanosome variant surface glycoprotein C-terminal domain FHIPEP PF00771.15 CDI86499.1 - 9.9 4.3 10.1 10 4.2 7.0 1.0 1 0 0 1 1 1 0 FHIPEP family DUF913 PF06025.7 CDI86499.1 - 10 4.7 7.9 11 4.6 5.5 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) RNA_pol_Rpc34 PF05158.7 CDI86500.1 - 2.3e-21 76.3 2.9 2.4e-09 36.8 0.3 3.6 1 1 2 3 3 3 3 RNA polymerase Rpc34 subunit Caudo_TAP PF02413.12 CDI86500.1 - 0.04 14.0 0.2 0.083 13.0 0.1 1.5 1 1 0 1 1 1 0 Caudovirales tail fibre assembly protein UBA_3 PF09288.5 CDI86500.1 - 0.05 13.2 0.0 0.13 11.9 0.0 1.6 1 0 0 1 1 1 0 Fungal ubiquitin-associated domain Opiods_neuropep PF01160.13 CDI86500.1 - 0.053 13.2 0.1 0.25 11.1 0.0 2.1 2 0 0 2 2 2 0 Vertebrate endogenous opioids neuropeptide MIP-T3 PF10243.4 CDI86501.1 - 1.5 7.1 57.0 1.9 6.8 39.5 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Trypan_PARP PF05887.6 CDI86502.1 - 0.017 14.9 0.8 0.02 14.7 0.5 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) RR_TM4-6 PF06459.7 CDI86502.1 - 0.23 11.3 9.3 0.25 11.1 6.5 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Zip PF02535.17 CDI86502.1 - 0.24 10.3 4.9 0.24 10.3 3.4 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Suf PF05843.9 CDI86502.1 - 0.39 10.3 5.3 0.4 10.3 3.7 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Hid1 PF12722.2 CDI86502.1 - 0.64 7.6 3.7 0.6 7.7 2.5 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein PAT1 PF09770.4 CDI86502.1 - 1.1 7.3 17.4 1.3 7.2 12.0 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF4175 PF13779.1 CDI86502.1 - 4.1 4.9 18.9 5.6 4.5 13.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) SelP_N PF04592.9 CDI86502.1 - 7.6 5.8 13.4 9.6 5.5 9.3 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Merozoite_SPAM PF07133.6 CDI86503.1 - 0.0033 17.3 2.2 0.0037 17.1 1.5 1.0 1 0 0 1 1 1 1 Merozoite surface protein (SPAM) CDC45 PF02724.9 CDI86503.1 - 0.034 12.2 3.4 0.034 12.1 2.3 1.0 1 0 0 1 1 1 0 CDC45-like protein Myc_N PF01056.13 CDI86503.1 - 0.036 13.2 1.9 0.039 13.1 1.3 1.2 1 0 0 1 1 1 0 Myc amino-terminal region GRP PF07172.6 CDI86503.1 - 0.11 13.0 0.6 0.19 12.2 0.4 1.4 1 0 0 1 1 1 0 Glycine rich protein family Ribosomal_60s PF00428.14 CDI86503.1 - 2.8 8.4 19.6 3.1 8.2 4.4 2.1 2 0 0 2 2 2 0 60s Acidic ribosomal protein BRF1 PF07741.8 CDI86504.1 - 2 8.6 21.0 2.5 8.3 14.6 1.2 1 0 0 1 1 1 0 Brf1-like TBP-binding domain SeqA PF03925.8 CDI86504.1 - 2.1 7.9 19.0 2.2 7.9 13.2 1.1 1 0 0 1 1 1 0 SeqA protein DUF1510 PF07423.6 CDI86504.1 - 2.7 7.3 22.3 2.9 7.1 15.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) ATAD4 PF15321.1 CDI86504.1 - 3.2 8.8 17.8 4.3 8.3 12.4 1.3 1 0 0 1 1 1 0 ATPase family AAA domain containing 4 Vfa1 PF08432.5 CDI86504.1 - 3.3 7.7 20.8 3.3 7.6 14.4 1.0 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 FYDLN_acid PF09538.5 CDI86504.1 - 4.8 7.7 12.6 5.5 7.6 8.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) YqfQ PF14181.1 CDI86504.1 - 4.9 7.1 23.5 5.3 7.0 16.3 1.0 1 0 0 1 1 1 0 YqfQ-like protein DUF1764 PF08576.5 CDI86504.1 - 5.2 7.9 23.9 6.1 7.6 16.6 1.1 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) UBN_AB PF14075.1 CDI86504.1 - 5.2 6.6 17.5 5.7 6.5 12.1 1.1 1 0 0 1 1 1 0 Ubinuclein conserved middle domain FAM176 PF14851.1 CDI86504.1 - 5.6 6.6 13.6 7 6.3 9.5 1.1 1 0 0 1 1 1 0 FAM176 family Dala_Dala_lig_N PF01820.16 CDI86504.1 - 6.8 7.0 11.5 9.6 6.5 8.0 1.3 1 0 0 1 1 1 0 D-ala D-ala ligase N-terminus RED_N PF07808.8 CDI86504.1 - 7 5.7 30.7 8.4 5.5 21.3 1.1 1 0 0 1 1 1 0 RED-like protein N-terminal region FimP PF09766.4 CDI86504.1 - 7.1 5.5 35.7 8.9 5.2 24.8 1.1 1 0 0 1 1 1 0 Fms-interacting protein AIF_C PF14721.1 CDI86504.1 - 8.1 6.7 18.0 9.5 6.4 12.4 1.1 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Pox_Ag35 PF03286.9 CDI86504.1 - 8.9 5.7 15.8 8.9 5.7 10.9 1.0 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DDHD PF02862.12 CDI86504.1 - 9.1 6.0 21.1 8.6 6.0 14.7 1.0 1 0 0 1 1 1 0 DDHD domain Corona_nucleoca PF00937.13 CDI86505.1 - 0.00018 20.5 17.7 0.00022 20.3 12.3 1.0 1 0 0 1 1 1 1 Coronavirus nucleocapsid protein TMEM51 PF15345.1 CDI86505.1 - 0.0002 21.1 12.0 0.00025 20.8 8.4 1.1 1 0 0 1 1 1 1 Transmembrane protein 51 PAT1 PF09770.4 CDI86505.1 - 0.0018 16.6 23.5 0.0018 16.6 16.3 1.2 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 SAGA-Tad1 PF12767.2 CDI86505.1 - 0.0034 17.1 15.9 0.0039 16.8 11.0 1.0 1 0 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit Conotoxin PF02950.12 CDI86505.1 - 0.0058 17.3 22.1 0.0058 17.3 15.3 1.9 2 1 0 2 2 1 1 Conotoxin RED_N PF07808.8 CDI86505.1 - 0.012 14.8 14.3 0.013 14.7 9.9 1.2 1 0 0 1 1 1 0 RED-like protein N-terminal region GRP PF07172.6 CDI86505.1 - 0.015 15.7 0.4 0.026 14.9 0.3 1.5 1 0 0 1 1 1 0 Glycine rich protein family RR_TM4-6 PF06459.7 CDI86505.1 - 0.022 14.6 5.4 0.024 14.5 3.8 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Raftlin PF15250.1 CDI86505.1 - 0.022 13.2 10.3 0.026 13.0 7.1 1.0 1 0 0 1 1 1 0 Raftlin CagX PF03524.10 CDI86505.1 - 0.024 13.9 3.4 0.026 13.7 2.3 1.2 1 0 0 1 1 1 0 Conjugal transfer protein DHHW PF14286.1 CDI86505.1 - 0.026 13.8 4.5 0.034 13.4 3.2 1.2 1 0 0 1 1 1 0 DHHW protein Peptidase_S49_N PF08496.5 CDI86505.1 - 0.026 14.3 5.6 0.033 13.9 3.9 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Herpes_DNAp_acc PF04929.7 CDI86505.1 - 0.031 13.2 4.4 0.045 12.7 3.1 1.3 1 1 0 1 1 1 0 Herpes DNA replication accessory factor K_trans PF02705.11 CDI86505.1 - 0.031 12.6 2.7 0.039 12.3 1.8 1.1 1 0 0 1 1 1 0 K+ potassium transporter DUF3260 PF11658.3 CDI86505.1 - 0.032 12.4 9.3 0.039 12.1 6.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3260) Suf PF05843.9 CDI86505.1 - 0.032 13.9 15.2 0.043 13.5 10.5 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) FHIPEP PF00771.15 CDI86505.1 - 0.05 11.9 6.5 0.059 11.6 4.5 1.1 1 0 0 1 1 1 0 FHIPEP family FimP PF09766.4 CDI86505.1 - 0.053 12.5 22.4 0.068 12.2 15.5 1.1 1 0 0 1 1 1 0 Fms-interacting protein SID-1_RNA_chan PF13965.1 CDI86505.1 - 0.064 11.4 3.0 0.067 11.3 2.1 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 AUX_IAA PF02309.11 CDI86505.1 - 0.071 12.8 8.5 0.088 12.5 5.9 1.1 1 0 0 1 1 1 0 AUX/IAA family DUF4175 PF13779.1 CDI86505.1 - 0.075 10.7 37.2 0.083 10.5 25.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) FLO_LFY PF01698.11 CDI86505.1 - 0.078 11.8 8.6 0.089 11.6 6.0 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein Ycf1 PF05758.7 CDI86505.1 - 0.079 10.6 6.7 0.08 10.6 4.7 1.0 1 0 0 1 1 1 0 Ycf1 DUF4407 PF14362.1 CDI86505.1 - 0.1 11.5 12.4 0.12 11.2 8.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) EPL1 PF10513.4 CDI86505.1 - 0.1 12.8 10.9 0.13 12.4 7.6 1.1 1 0 0 1 1 1 0 Enhancer of polycomb-like PUCC PF03209.10 CDI86505.1 - 0.12 11.0 3.8 0.14 10.8 2.7 1.1 1 0 0 1 1 1 0 PUCC protein Zip PF02535.17 CDI86505.1 - 0.12 11.3 3.0 0.15 11.0 2.0 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter DcuC PF03606.10 CDI86505.1 - 0.13 10.4 0.9 0.14 10.3 0.6 1.0 1 0 0 1 1 1 0 C4-dicarboxylate anaerobic carrier BAF1_ABF1 PF04684.8 CDI86505.1 - 0.13 11.0 29.8 0.14 10.9 20.7 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor AAA_23 PF13476.1 CDI86505.1 - 0.14 12.5 15.4 0.18 12.1 10.7 1.2 1 0 0 1 1 1 0 AAA domain ALG3 PF05208.8 CDI86505.1 - 0.14 11.3 3.8 0.16 11.1 2.6 1.1 1 0 0 1 1 1 0 ALG3 protein ABC2_membrane_2 PF12679.2 CDI86505.1 - 0.16 10.8 1.3 0.19 10.5 0.9 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF897 PF05982.7 CDI86505.1 - 0.17 10.6 1.5 0.2 10.3 1.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF897) DUF1266 PF06889.6 CDI86505.1 - 0.18 11.6 7.0 0.21 11.3 4.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1266) Apt1 PF10351.4 CDI86505.1 - 0.22 10.3 11.8 0.27 10.0 8.2 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF2126 PF09899.4 CDI86505.1 - 0.3 9.0 5.5 0.3 9.0 3.8 1.0 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) EIIBC-GUT_N PF03612.9 CDI86505.1 - 0.3 10.6 8.1 0.43 10.1 5.6 1.3 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus DUF4512 PF14975.1 CDI86505.1 - 0.33 11.7 8.1 0.071 13.9 2.5 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4512) PH_4 PF15404.1 CDI86505.1 - 0.45 10.0 13.5 0.066 12.7 6.9 1.4 2 0 0 2 2 1 0 Pleckstrin homology domain CD20 PF04103.10 CDI86505.1 - 0.49 10.3 13.4 0.37 10.7 5.5 2.0 1 1 1 2 2 2 0 CD20-like family Cas1_AcylT PF07779.7 CDI86505.1 - 0.57 8.5 2.8 0.65 8.3 1.9 1.1 1 0 0 1 1 1 0 10 TM Acyl Transferase domain found in Cas1p Peptidase_U57 PF05582.7 CDI86505.1 - 0.59 9.0 6.6 0.65 8.9 4.6 1.1 1 0 0 1 1 1 0 YabG peptidase U57 Herpes_UL87 PF03043.9 CDI86505.1 - 0.64 8.3 6.4 0.72 8.1 4.4 1.1 1 0 0 1 1 1 0 Herpesvirus UL87 family Apc15p PF05841.6 CDI86505.1 - 0.73 10.5 20.6 1.8 9.2 9.7 2.1 2 0 0 2 2 2 0 Apc15p protein DUF3801 PF12687.2 CDI86505.1 - 0.82 9.2 12.2 1.3 8.5 8.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3801) Herpes_glycop PF01528.11 CDI86505.1 - 1.1 7.9 3.4 1.2 7.7 2.4 1.2 1 0 0 1 1 1 0 Herpesvirus glycoprotein M DUF2149 PF09919.4 CDI86505.1 - 1.3 9.1 8.4 2 8.5 5.9 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2149) Anoctamin PF04547.7 CDI86505.1 - 1.4 7.5 13.0 1.6 7.2 9.0 1.0 1 0 0 1 1 1 0 Calcium-activated chloride channel DUF3306 PF11748.3 CDI86505.1 - 1.7 9.3 13.2 2.9 8.5 9.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3306) eIF-3_zeta PF05091.7 CDI86505.1 - 1.7 7.1 15.8 2 6.9 11.0 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF912 PF06024.7 CDI86505.1 - 2 8.4 15.0 26 4.9 10.0 2.1 1 1 1 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) ATAD4 PF15321.1 CDI86505.1 - 2.1 9.4 14.9 2.5 9.1 7.3 2.1 2 0 0 2 2 2 0 ATPase family AAA domain containing 4 YfhO PF09586.5 CDI86505.1 - 2.2 6.1 12.1 2.8 5.8 8.4 1.0 1 0 0 1 1 1 0 Bacterial membrane protein YfhO Hid1 PF12722.2 CDI86505.1 - 2.2 5.8 15.8 2.9 5.4 11.0 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF3530 PF12048.3 CDI86505.1 - 2.3 7.0 22.9 0.15 10.9 12.7 1.4 2 0 0 2 2 1 0 Protein of unknown function (DUF3530) Presenilin PF01080.12 CDI86505.1 - 2.5 6.8 6.3 3.2 6.4 4.4 1.2 1 0 0 1 1 1 0 Presenilin DUF4228 PF14009.1 CDI86505.1 - 2.5 8.2 12.7 3.8 7.6 8.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4228) Peroxin-13_N PF04088.8 CDI86505.1 - 3 7.7 10.3 2.4 8.0 6.4 1.4 1 1 0 1 1 1 0 Peroxin 13, N-terminal region Zn_peptidase PF04228.8 CDI86505.1 - 3.1 6.9 14.8 8.1 5.5 10.3 1.7 1 1 0 1 1 1 0 Putative neutral zinc metallopeptidase 7tm_7 PF08395.7 CDI86505.1 - 4 6.3 15.0 4.3 6.2 10.4 1.1 1 0 0 1 1 1 0 7tm Chemosensory receptor Het-C PF07217.6 CDI86505.1 - 4 5.5 8.4 4.4 5.3 5.8 1.1 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C DUF3276 PF11680.3 CDI86505.1 - 4.1 7.2 9.4 4.4 7.1 5.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3276) DUF3357 PF11837.3 CDI86505.1 - 4.5 7.1 13.2 35 4.2 8.9 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3357) TMEM154 PF15102.1 CDI86505.1 - 4.8 6.8 16.6 23 4.6 11.5 1.8 1 1 0 1 1 1 0 TMEM154 protein family SHR3_chaperone PF08229.6 CDI86505.1 - 5 6.0 17.9 6.9 5.5 12.4 1.2 1 0 0 1 1 1 0 ER membrane protein SH3 WASH-7_C PF14746.1 CDI86505.1 - 7 6.2 13.6 10 5.7 9.4 1.2 1 0 0 1 1 1 0 WASH complex subunit 7, C-terminal PigN PF04987.9 CDI86505.1 - 7.2 5.1 7.2 9.8 4.6 5.0 1.2 1 0 0 1 1 1 0 Phosphatidylinositolglycan class N (PIG-N) Folate_carrier PF01770.13 CDI86505.1 - 8.6 4.7 12.8 9.2 4.6 8.5 1.2 1 1 0 1 1 1 0 Reduced folate carrier DUF4557 PF15101.1 CDI86505.1 - 9.7 5.9 28.5 0.34 10.7 15.7 1.5 2 0 0 2 2 1 0 Domain of unknown function (DUF4557) FAM176 PF14851.1 CDI86505.1 - 9.7 5.8 11.0 2.3 7.8 5.3 1.6 1 1 1 2 2 2 0 FAM176 family Peptidase_S15 PF02129.13 CDI86505.1 - 9.9 5.4 12.2 12 5.1 8.4 1.1 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) MitoNEET_N PF10660.4 CDI86506.1 - 0.084 12.7 0.1 0.17 11.7 0.1 1.4 1 0 0 1 1 1 0 Iron-containing outer mitochondrial membrane protein N-terminus DUF202 PF02656.10 CDI86506.1 - 0.19 11.9 0.6 0.33 11.1 0.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF202) DUF3739 PF12545.3 CDI86508.1 - 0.0087 16.1 1.7 0.025 14.7 1.2 1.7 1 0 0 1 1 1 1 Filamentous haemagglutinin family outer membrane protein DUF2052 PF09747.4 CDI86508.1 - 0.046 13.6 35.7 0.34 10.8 11.0 3.1 3 0 0 3 3 3 0 Coiled-coil domain containing protein (DUF2052) Ndc1_Nup PF09531.5 CDI86508.1 - 2.4 6.4 25.6 0.22 9.9 6.9 2.1 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup APC_CDC26 PF10471.4 CDI86508.1 - 6.5 7.5 62.3 1.6 9.5 3.2 4.7 4 0 0 4 4 4 0 Anaphase-promoting complex APC subunit 1 SAGA-Tad1 PF12767.2 CDI86509.1 - 0.029 14.0 1.7 0.027 14.1 1.2 1.1 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit BAF1_ABF1 PF04684.8 CDI86509.1 - 0.029 13.2 21.0 0.038 12.8 14.6 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor eIF-3c_N PF05470.7 CDI86509.1 - 0.053 11.6 3.6 0.055 11.5 2.5 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Spore_YhcN_YlaJ PF09580.5 CDI86509.1 - 0.1 12.6 5.4 0.11 12.5 3.7 1.1 1 0 0 1 1 1 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) Tom22 PF04281.8 CDI86509.1 - 0.25 10.8 3.8 0.32 10.5 2.6 1.2 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 Med15 PF09606.5 CDI86509.1 - 0.3 9.2 23.0 0.35 9.0 15.9 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal FAM176 PF14851.1 CDI86509.1 - 0.41 10.3 3.0 0.44 10.2 2.1 1.1 1 0 0 1 1 1 0 FAM176 family Hid1 PF12722.2 CDI86509.1 - 1.2 6.7 3.3 1.1 6.7 2.3 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein FimP PF09766.4 CDI86509.1 - 1.4 7.9 12.9 1.6 7.7 8.9 1.0 1 0 0 1 1 1 0 Fms-interacting protein Activator_LAG-3 PF11498.3 CDI86509.1 - 1.7 7.2 19.5 1.8 7.1 13.5 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 vMSA PF00695.14 CDI86509.1 - 1.8 7.6 3.5 2 7.5 2.4 1.0 1 0 0 1 1 1 0 Major surface antigen from hepadnavirus Suf PF05843.9 CDI86509.1 - 1.9 8.1 8.2 2 8.0 5.7 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF1682 PF07946.9 CDI86509.1 - 2.3 7.0 5.3 2.4 6.8 3.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) DUF4557 PF15101.1 CDI86509.1 - 2.3 8.0 13.1 2.9 7.6 9.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) Gly-zipper_OmpA PF13436.1 CDI86509.1 - 2.6 7.7 35.0 4.9 6.8 24.2 1.5 1 1 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain UPF0560 PF10577.4 CDI86509.1 - 2.9 6.0 10.7 3.4 5.8 7.4 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 PAT1 PF09770.4 CDI86509.1 - 3.4 5.7 16.2 3.5 5.7 11.2 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 RR_TM4-6 PF06459.7 CDI86509.1 - 4.3 7.1 7.3 4.4 7.1 5.1 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 AICARFT_IMPCHas PF01808.13 CDI86509.1 - 4.4 6.3 13.0 5 6.1 9.0 1.0 1 0 0 1 1 1 0 AICARFT/IMPCHase bienzyme TFIIA PF03153.8 CDI86509.1 - 6 6.6 17.5 6.3 6.5 12.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Glyco_transf_15 PF01793.11 CDI86509.1 - 6.1 5.6 5.8 7 5.4 4.1 1.0 1 0 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase CDK2AP PF09806.4 CDI86509.1 - 6.5 6.9 18.6 8.5 6.5 12.9 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein CDK5_activator PF03261.10 CDI86509.1 - 8.2 5.6 8.4 8.9 5.5 5.8 1.0 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein Spt20 PF12090.3 CDI86509.1 - 8.5 5.6 10.0 9.5 5.5 6.9 1.1 1 0 0 1 1 1 0 Spt20 family AAA_11 PF13086.1 CDI86510.1 - 2.8e-16 59.8 0.0 2.8e-16 59.8 0.0 5.0 3 2 0 3 3 3 1 AAA domain Med15 PF09606.5 CDI86510.1 - 3.8e-05 22.1 47.8 3.8e-05 22.1 33.1 2.0 2 0 0 2 2 2 2 ARC105 or Med15 subunit of Mediator complex non-fungal UPF0564 PF10595.4 CDI86510.1 - 0.0014 17.6 37.2 0.0014 17.6 25.8 2.7 2 1 0 2 2 2 1 Uncharacterised protein family UPF0564 PAT1 PF09770.4 CDI86510.1 - 5.3 5.1 109.1 0.19 9.9 40.3 2.1 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 Utp14 PF04615.8 CDI86510.1 - 9.5 4.2 68.6 0.059 11.5 19.1 2.9 3 0 0 3 3 3 0 Utp14 protein DUF3568 PF12092.3 CDI86511.1 - 0.086 12.5 0.3 0.21 11.2 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3568) DUF4208 PF13907.1 CDI86511.1 - 0.24 11.6 7.1 2.5 8.3 0.1 3.9 4 0 0 4 4 4 0 Domain of unknown function (DUF4208) DUF2408 PF10303.4 CDI86511.1 - 0.27 11.3 4.4 0.11 12.6 0.2 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF2408) Helicase_C_2 PF13307.1 CDI86513.1 - 2.2e-36 125.3 1.2 3.9e-35 121.2 0.0 2.9 2 1 0 2 2 2 1 Helicase C-terminal domain DEAD_2 PF06733.10 CDI86513.1 - 5e-29 100.9 0.1 1.5e-28 99.3 0.0 1.9 2 0 0 2 2 2 1 DEAD_2 DEAD PF00270.24 CDI86513.1 - 6.7e-05 22.4 0.4 0.0007 19.1 0.4 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase Tox-GHH2 PF15635.1 CDI86513.1 - 0.0059 16.9 0.0 0.0059 16.9 0.0 3.3 3 0 0 3 3 3 1 GHH signature containing HNH/Endo VII superfamily nuclease toxin 2 ResIII PF04851.10 CDI86513.1 - 0.0081 16.0 2.3 3.3 7.5 1.8 2.9 2 1 0 2 2 2 2 Type III restriction enzyme, res subunit Toxin_39 PF15500.1 CDI86516.1 - 0.39 10.8 4.3 2.1 8.5 0.1 3.3 2 0 0 2 2 2 0 Putative RNase-like toxin V-SNARE PF05008.10 CDI86516.1 - 5.4 7.2 11.8 0.13 12.3 0.5 3.8 4 0 0 4 4 4 0 Vesicle transport v-SNARE protein N-terminus Mito_carr PF00153.22 CDI86518.1 - 8.4e-31 105.5 0.6 4.6e-15 55.0 0.1 2.3 2 0 0 2 2 2 2 Mitochondrial carrier protein BSP_II PF05432.6 CDI86519.1 - 0.022 14.0 40.9 0.024 13.9 28.3 1.1 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Peptidase_C14 PF00656.17 CDI86519.1 - 0.22 11.2 1.0 0.22 11.1 0.7 1.1 1 0 0 1 1 1 0 Caspase domain BUD22 PF09073.5 CDI86519.1 - 0.28 10.2 27.2 0.3 10.1 18.8 1.0 1 0 0 1 1 1 0 BUD22 Mpp10 PF04006.7 CDI86519.1 - 1.1 7.5 27.2 1.2 7.4 18.9 1.0 1 0 0 1 1 1 0 Mpp10 protein PepSY_2 PF13670.1 CDI86519.1 - 1.2 9.1 23.0 2 8.3 0.6 2.1 2 0 0 2 2 2 0 Peptidase propeptide and YPEB domain Daxx PF03344.10 CDI86519.1 - 2 6.8 35.9 2.2 6.6 24.9 1.0 1 0 0 1 1 1 0 Daxx Family SID-1_RNA_chan PF13965.1 CDI86519.1 - 2.1 6.3 4.0 2.2 6.3 2.8 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 SDA1 PF05285.7 CDI86519.1 - 3.1 7.0 33.8 3.4 6.8 23.4 1.0 1 0 0 1 1 1 0 SDA1 FGF-BP1 PF06473.7 CDI86519.1 - 3.1 7.3 14.8 3.6 7.1 10.2 1.2 1 0 0 1 1 1 0 FGF binding protein 1 (FGF-BP1) Paf1 PF03985.8 CDI86519.1 - 3.8 6.1 28.2 5 5.7 19.5 1.2 1 0 0 1 1 1 0 Paf1 Ycf1 PF05758.7 CDI86519.1 - 3.9 5.0 16.9 3.7 5.1 11.7 1.0 1 0 0 1 1 1 0 Ycf1 RskA PF10099.4 CDI86519.1 - 4 7.1 13.0 33 4.1 0.3 2.0 1 1 1 2 2 2 0 Anti-sigma-K factor rskA IFT57 PF10498.4 CDI86519.1 - 4.2 6.0 15.6 4.2 6.0 10.8 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 DUF4246 PF14033.1 CDI86519.1 - 5.9 5.3 8.8 7.1 5.1 6.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4246) CobT PF06213.7 CDI86519.1 - 6.1 5.8 35.9 7.1 5.6 24.9 1.0 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF3292 PF11696.3 CDI86520.1 - 0.0038 15.1 1.1 0.0046 14.8 0.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3292) UvrD-helicase PF00580.16 CDI86520.1 - 0.017 14.4 13.3 0.018 14.3 9.2 1.1 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain Fumble PF03630.9 CDI86520.1 - 0.04 12.7 3.5 0.053 12.3 2.5 1.1 1 0 0 1 1 1 0 Fumble Ndc1_Nup PF09531.5 CDI86520.1 - 0.045 12.1 14.8 0.056 11.8 10.2 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup SGT1 PF07093.6 CDI86520.1 - 0.14 10.5 13.6 0.16 10.3 9.4 1.0 1 0 0 1 1 1 0 SGT1 protein Hid1 PF12722.2 CDI86520.1 - 0.3 8.7 12.3 0.33 8.5 8.5 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein AUX_IAA PF02309.11 CDI86520.1 - 0.44 10.2 8.4 0.66 9.6 5.8 1.3 1 0 0 1 1 1 0 AUX/IAA family Herpes_UL87 PF03043.9 CDI86520.1 - 0.61 8.4 5.9 0.76 8.0 4.1 1.1 1 0 0 1 1 1 0 Herpesvirus UL87 family DDRGK PF09756.4 CDI86520.1 - 1.1 8.6 17.5 1.8 7.9 12.1 1.3 1 0 0 1 1 1 0 DDRGK domain TFIIA PF03153.8 CDI86520.1 - 1.1 9.0 30.8 1.5 8.6 21.3 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Neur_chan_memb PF02932.11 CDI86520.1 - 1.3 8.8 12.3 1.7 8.5 8.5 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region FLO_LFY PF01698.11 CDI86520.1 - 1.3 7.7 11.8 1.8 7.3 8.2 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein Herpes_DNAp_acc PF04929.7 CDI86520.1 - 1.9 7.4 14.2 2.4 7.0 9.8 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor GAGA_bind PF06217.7 CDI86520.1 - 1.9 8.4 14.0 2.2 8.1 9.7 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family Anoctamin PF04547.7 CDI86520.1 - 2 7.0 10.0 2.3 6.7 7.0 1.2 1 0 0 1 1 1 0 Calcium-activated chloride channel eIF-3_zeta PF05091.7 CDI86520.1 - 2.6 6.5 15.9 3.4 6.1 11.0 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF4175 PF13779.1 CDI86520.1 - 3.2 5.3 50.4 3.8 5.0 34.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) ORC5_C PF14630.1 CDI86520.1 - 3.9 6.8 15.8 42 3.4 10.9 2.0 1 1 0 1 1 1 0 Origin recognition complex (ORC) subunit 5 C-terminus FUSC PF04632.7 CDI86520.1 - 6.8 4.9 19.8 9.7 4.4 13.7 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family Paramyxo_ncap PF00973.14 CDI86520.1 - 6.9 5.2 7.9 7.9 5.0 5.5 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein BTV_NS2 PF04514.7 CDI86520.1 - 8.2 5.2 12.8 11 4.7 8.9 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 HD_assoc PF13286.1 CDI86520.1 - 8.5 6.7 14.7 1.5 9.1 5.7 2.5 2 1 1 3 3 3 0 Phosphohydrolase-associated domain SR-25 PF10500.4 CDI86523.1 - 0.00018 21.0 20.7 0.00034 20.1 14.4 1.4 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein DUF4175 PF13779.1 CDI86523.1 - 0.073 10.7 40.6 0.091 10.4 28.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) FAM60A PF15396.1 CDI86523.1 - 0.11 12.1 16.9 0.11 12.1 11.7 1.1 1 0 0 1 1 1 0 Protein Family FAM60A CDC45 PF02724.9 CDI86523.1 - 0.16 10.0 14.4 0.17 9.9 10.0 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF4603 PF15376.1 CDI86523.1 - 0.17 9.0 12.1 0.16 9.1 8.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) Bud13 PF09736.4 CDI86523.1 - 0.22 11.7 18.0 0.23 11.7 12.5 1.2 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex DUF2052 PF09747.4 CDI86523.1 - 0.27 11.1 18.2 0.3 10.9 12.6 1.1 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) Spc7_N PF15402.1 CDI86523.1 - 0.41 8.5 21.8 0.47 8.4 15.1 1.0 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 DDRGK PF09756.4 CDI86523.1 - 0.45 9.9 17.1 0.52 9.6 11.9 1.1 1 0 0 1 1 1 0 DDRGK domain SoxE PF06525.6 CDI86523.1 - 0.51 9.5 4.3 0.62 9.3 3.0 1.3 1 0 0 1 1 1 0 Sulfocyanin (SoxE) PAT1 PF09770.4 CDI86523.1 - 0.59 8.3 38.2 0.58 8.3 26.4 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Hid1 PF12722.2 CDI86523.1 - 0.7 7.4 22.2 0.66 7.5 15.4 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein FLO_LFY PF01698.11 CDI86523.1 - 0.72 8.6 11.7 0.74 8.5 8.1 1.2 1 0 0 1 1 1 0 Floricaula / Leafy protein DUF1510 PF07423.6 CDI86523.1 - 0.83 8.9 19.0 0.95 8.7 13.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Pex16 PF08610.5 CDI86523.1 - 0.98 8.3 15.8 1 8.2 10.9 1.1 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) FAM176 PF14851.1 CDI86523.1 - 1 9.0 9.5 1.5 8.5 6.6 1.4 1 0 0 1 1 1 0 FAM176 family NST1 PF13945.1 CDI86523.1 - 1.2 9.1 24.6 1.4 8.9 17.0 1.1 1 0 0 1 1 1 0 Salt tolerance down-regulator Plasmodium_Vir PF05795.6 CDI86523.1 - 1.2 8.2 10.8 1.4 8.0 7.5 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Lin-8 PF03353.10 CDI86523.1 - 1.3 8.2 22.3 1.3 8.2 15.4 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Draxin PF15550.1 CDI86523.1 - 1.4 8.5 12.8 1.5 8.4 8.8 1.1 1 0 0 1 1 1 0 Draxin Mem_trans PF03547.13 CDI86523.1 - 1.7 6.8 12.7 1.7 6.8 8.8 1.1 1 0 0 1 1 1 0 Membrane transport protein Afi1 PF07792.7 CDI86523.1 - 1.8 8.5 16.0 2.8 7.9 11.1 1.3 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Macoilin PF09726.4 CDI86523.1 - 1.9 6.6 22.6 2.5 6.2 15.7 1.2 1 0 0 1 1 1 0 Transmembrane protein DDHD PF02862.12 CDI86523.1 - 2 8.1 17.7 2.4 7.8 12.3 1.2 1 0 0 1 1 1 0 DDHD domain Cwf_Cwc_15 PF04889.7 CDI86523.1 - 2.1 7.9 21.8 2.7 7.6 15.1 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF4647 PF15504.1 CDI86523.1 - 2.2 7.0 20.3 2.2 7.0 14.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4647) CDK5_activator PF03261.10 CDI86523.1 - 2.4 7.4 20.2 2.5 7.3 14.0 1.0 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein DUF755 PF05501.6 CDI86523.1 - 2.5 8.1 41.9 1.4 8.9 28.1 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF755) DUF572 PF04502.8 CDI86523.1 - 2.7 7.1 19.4 3 6.9 13.4 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Spore_coat_CotO PF14153.1 CDI86523.1 - 2.7 7.3 22.6 2.9 7.2 15.6 1.2 1 0 0 1 1 1 0 Spore coat protein CotO TMEM51 PF15345.1 CDI86523.1 - 2.8 7.5 24.8 3.1 7.4 17.2 1.0 1 0 0 1 1 1 0 Transmembrane protein 51 PIH1 PF08190.7 CDI86523.1 - 3 7.2 22.9 3.2 7.0 15.9 1.1 1 0 0 1 1 1 0 pre-RNA processing PIH1/Nop17 Utp14 PF04615.8 CDI86523.1 - 3 5.8 24.5 3.2 5.8 17.0 1.0 1 0 0 1 1 1 0 Utp14 protein FCP1_C PF09309.5 CDI86523.1 - 3 7.0 23.7 4.4 6.5 16.4 1.3 1 1 0 1 1 1 0 FCP1, C-terminal CytochromB561_N PF09786.4 CDI86523.1 - 3.1 6.1 18.1 3 6.1 12.5 1.0 1 0 0 1 1 1 0 Cytochrome B561, N terminal PLRV_ORF5 PF01690.12 CDI86523.1 - 3.1 6.8 19.1 3.3 6.7 13.2 1.0 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein DNA_pol_viral_N PF00242.12 CDI86523.1 - 3.2 6.6 20.8 3.1 6.7 14.4 1.0 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain DUF2146 PF10220.4 CDI86523.1 - 3.3 5.5 19.1 3.7 5.4 13.3 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2146) DUF2217 PF10265.4 CDI86523.1 - 3.4 6.3 18.1 3.7 6.2 12.5 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) DUF4045 PF13254.1 CDI86523.1 - 3.5 6.8 20.3 3.6 6.7 14.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Neur_chan_memb PF02932.11 CDI86523.1 - 3.6 7.3 15.3 3.7 7.3 10.6 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF1675 PF07897.6 CDI86523.1 - 3.8 7.2 16.3 4.7 7.0 11.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) DUF966 PF06136.8 CDI86523.1 - 4.1 6.7 24.4 4.6 6.5 16.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF966) SPX PF03105.14 CDI86523.1 - 4.2 7.0 17.3 4.8 6.8 12.0 1.1 1 0 0 1 1 1 0 SPX domain DUF822 PF05687.8 CDI86523.1 - 4.7 7.5 19.3 5.8 7.2 13.4 1.2 1 0 0 1 1 1 0 Plant protein of unknown function (DUF822) Tetraspannin PF00335.15 CDI86523.1 - 5.3 6.2 6.4 5.8 6.1 4.4 1.1 1 0 0 1 1 1 0 Tetraspanin family TT_ORF1 PF02956.9 CDI86523.1 - 5.4 5.3 13.2 6 5.1 9.2 1.0 1 0 0 1 1 1 0 TT viral orf 1 Herpes_env PF01673.13 CDI86523.1 - 5.4 5.4 18.5 5.5 5.4 12.8 1.0 1 0 0 1 1 1 0 Herpesvirus putative major envelope glycoprotein DHHW PF14286.1 CDI86523.1 - 6.4 5.9 18.6 7.6 5.7 12.9 1.1 1 0 0 1 1 1 0 DHHW protein SAPS PF04499.10 CDI86523.1 - 7 5.1 18.0 6.9 5.1 12.5 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein tRNA-synt_1 PF00133.17 CDI86523.1 - 7.3 4.4 8.9 8.5 4.2 6.2 1.0 1 0 0 1 1 1 0 tRNA synthetases class I (I, L, M and V) Raftlin PF15250.1 CDI86523.1 - 8.4 4.7 17.7 8.9 4.7 12.3 1.1 1 0 0 1 1 1 0 Raftlin YjgP_YjgQ PF03739.9 CDI86523.1 - 8.7 4.9 9.2 8.9 4.9 6.4 1.1 1 0 0 1 1 1 0 Predicted permease YjgP/YjgQ family Ndc1_Nup PF09531.5 CDI86523.1 - 9 4.5 20.5 8.6 4.6 14.2 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup RAP1 PF07218.6 CDI86523.1 - 9.4 4.1 12.1 9.6 4.1 8.4 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Miff PF05644.6 CDI86523.1 - 9.9 5.7 15.9 12 5.4 11.0 1.1 1 0 0 1 1 1 0 Mitochondrial and peroxisomal fission factor Mff DUF755 PF05501.6 CDI86524.1 - 0.00018 21.5 24.0 0.00018 21.5 16.7 15.7 8 3 4 12 12 12 1 Domain of unknown function (DUF755) CAF-1_p150 PF11600.3 CDI86524.1 - 0.0053 16.1 10.1 0.0053 16.1 7.0 11.0 5 3 3 8 8 8 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF952 PF06108.7 CDI86525.1 - 0.1 12.5 1.9 8.7 6.2 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF952) Pex14_N PF04695.8 CDI86526.1 - 0.0016 18.5 8.0 0.0016 18.5 5.5 7.7 5 2 2 7 7 7 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Serinc PF03348.10 CDI86526.1 - 0.0018 17.0 2.8 0.0018 17.0 1.9 3.4 3 0 0 3 3 3 2 Serine incorporator (Serinc) DUF755 PF05501.6 CDI86526.1 - 0.004 17.1 4.0 0.004 17.1 2.7 8.8 6 2 2 8 8 8 2 Domain of unknown function (DUF755) FAM176 PF14851.1 CDI86526.1 - 0.39 10.3 15.0 0.14 11.8 1.1 4.0 3 0 0 3 3 3 0 FAM176 family UPF0564 PF10595.4 CDI86527.1 - 0.00019 20.4 12.3 0.00019 20.4 8.5 3.3 3 0 0 3 3 3 2 Uncharacterised protein family UPF0564 DUF4484 PF14831.1 CDI86527.1 - 0.00055 20.0 6.6 0.00055 20.0 4.5 3.6 2 1 0 3 3 3 1 Domain of unknown function (DUF4484) DUF755 PF05501.6 CDI86528.1 - 0.00053 20.0 1.7 0.00053 20.0 1.2 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF755) TMEM51 PF15345.1 CDI86528.1 - 0.00093 18.9 12.2 0.041 13.5 0.2 2.1 2 0 0 2 2 2 2 Transmembrane protein 51 DUF1180 PF06679.7 CDI86528.1 - 0.0019 18.1 0.3 0.0019 18.1 0.2 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1180) HemY_N PF07219.8 CDI86528.1 - 0.0035 16.8 0.4 0.0035 16.8 0.3 2.4 2 1 0 2 2 1 1 HemY protein N-terminus DUF2514 PF10721.4 CDI86528.1 - 0.0035 17.0 2.5 0.0035 17.0 1.7 2.3 2 0 0 2 2 1 1 Protein of unknown function (DUF2514) DUF2681 PF10883.3 CDI86528.1 - 0.0045 17.1 12.9 0.02 15.0 0.1 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF2681) DUF1510 PF07423.6 CDI86528.1 - 0.0057 16.0 2.0 0.0057 16.0 1.4 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF1510) SpoIIIAH PF12685.2 CDI86528.1 - 0.0059 16.1 3.3 0.0059 16.1 2.3 2.0 1 1 1 2 2 2 1 SpoIIIAH-like protein Activator_LAG-3 PF11498.3 CDI86528.1 - 0.011 14.5 22.1 0.012 14.4 10.5 2.2 2 0 0 2 2 2 0 Transcriptional activator LAG-3 DUF2852 PF11014.3 CDI86528.1 - 0.013 15.4 1.5 0.3 11.0 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2852) Neur_chan_memb PF02932.11 CDI86528.1 - 0.017 14.9 2.2 0.023 14.5 1.5 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Herpes_gE PF02480.11 CDI86528.1 - 0.024 12.9 2.8 0.12 10.5 0.1 2.0 2 0 0 2 2 2 0 Alphaherpesvirus glycoprotein E Gly-zipper_OmpA PF13436.1 CDI86528.1 - 0.036 13.7 17.3 0.29 10.7 7.4 2.3 2 0 0 2 2 2 0 Glycine-zipper containing OmpA-like membrane domain DUF4446 PF14584.1 CDI86528.1 - 0.04 13.7 0.1 0.04 13.7 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) TMEM154 PF15102.1 CDI86528.1 - 0.052 13.2 0.4 0.052 13.2 0.2 2.5 2 1 0 2 2 2 0 TMEM154 protein family Macoilin PF09726.4 CDI86528.1 - 0.061 11.6 12.2 0.085 11.1 8.5 1.2 1 0 0 1 1 1 0 Transmembrane protein OAD_gamma PF04277.8 CDI86528.1 - 0.1 12.9 0.1 0.1 12.9 0.0 3.0 2 1 0 2 2 1 0 Oxaloacetate decarboxylase, gamma chain GRP PF07172.6 CDI86528.1 - 0.15 12.5 5.4 0.17 12.3 0.6 2.4 2 1 0 2 2 2 0 Glycine rich protein family Tmemb_9 PF05434.6 CDI86528.1 - 0.22 11.2 0.0 0.22 11.2 0.0 2.3 2 0 0 2 2 2 0 TMEM9 Apt1 PF10351.4 CDI86528.1 - 0.25 10.1 9.6 0.33 9.7 6.6 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain XRCC4 PF06632.7 CDI86528.1 - 0.41 9.4 11.6 0.53 9.0 8.1 1.1 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 DUF3801 PF12687.2 CDI86528.1 - 0.42 10.1 15.9 0.54 9.8 11.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3801) WBP-1 PF11669.3 CDI86528.1 - 0.42 10.7 0.1 0.42 10.7 0.0 2.8 2 1 0 2 2 1 0 WW domain-binding protein 1 Endonuc_Holl PF10107.4 CDI86528.1 - 0.48 10.1 9.6 1.3 8.6 0.2 2.1 2 0 0 2 2 2 0 Endonuclease related to archaeal Holliday junction resolvase Zip PF02535.17 CDI86528.1 - 0.54 9.2 12.7 1.2 8.1 8.8 1.5 1 1 0 1 1 1 0 ZIP Zinc transporter Dehydrin PF00257.14 CDI86528.1 - 0.74 10.1 19.3 1.5 9.1 13.4 1.3 1 1 0 1 1 1 0 Dehydrin OSTbeta PF15048.1 CDI86528.1 - 0.8 9.7 7.4 0.43 10.6 0.2 2.3 2 0 0 2 2 2 0 Organic solute transporter subunit beta protein DUF4512 PF14975.1 CDI86528.1 - 0.83 10.5 5.5 5.9 7.7 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4512) Ctr PF04145.10 CDI86528.1 - 0.92 9.5 13.8 0.072 13.1 0.3 2.2 1 1 0 2 2 2 0 Ctr copper transporter family Herpes_env PF01673.13 CDI86528.1 - 0.93 7.9 9.1 1.1 7.6 6.3 1.1 1 0 0 1 1 1 0 Herpesvirus putative major envelope glycoprotein SHR3_chaperone PF08229.6 CDI86528.1 - 1.4 7.8 14.5 0.12 11.2 0.2 2.2 2 0 0 2 2 2 0 ER membrane protein SH3 FAM176 PF14851.1 CDI86528.1 - 1.5 8.4 13.6 0.49 10.0 1.0 2.2 1 1 1 2 2 2 0 FAM176 family DUF4611 PF15387.1 CDI86528.1 - 1.7 8.8 11.9 0.6 10.3 4.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Bud13 PF09736.4 CDI86528.1 - 1.9 8.7 15.8 1.3 9.2 3.3 2.1 2 0 0 2 2 2 0 Pre-mRNA-splicing factor of RES complex NPR3 PF03666.8 CDI86528.1 - 2.2 6.7 14.2 1.1 7.7 3.7 2.0 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 Suf PF05843.9 CDI86528.1 - 2.4 7.8 11.9 3.4 7.3 8.3 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Cytadhesin_P30 PF07271.6 CDI86528.1 - 3 7.0 14.0 5.4 6.2 0.6 2.1 2 0 0 2 2 2 0 Cytadhesin P30/P32 CAF-1_p150 PF11600.3 CDI86528.1 - 3.1 7.1 28.4 0.025 13.9 9.4 2.0 1 1 1 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF3413 PF11893.3 CDI86528.1 - 3.3 6.5 6.6 1.3 7.8 1.5 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3413) Herpes_capsid PF06112.6 CDI86528.1 - 3.4 7.7 17.8 2 8.4 2.2 2.1 2 0 0 2 2 2 0 Gammaherpesvirus capsid protein Peptidase_S64 PF08192.6 CDI86528.1 - 4 5.6 12.0 5.1 5.2 8.3 1.2 1 0 0 1 1 1 0 Peptidase family S64 Herpes_UL17 PF04559.7 CDI86528.1 - 4.2 5.8 18.2 0.29 9.6 1.6 2.0 1 1 1 2 2 2 0 Herpesvirus UL17 protein DUF3306 PF11748.3 CDI86528.1 - 4.3 8.0 27.6 0.41 11.3 4.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3306) OATP PF03137.15 CDI86528.1 - 4.3 5.2 4.9 4.6 5.1 1.2 1.9 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family DUF3245 PF11595.3 CDI86528.1 - 4.4 7.5 19.5 2.3 8.4 6.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3245) Bap31 PF05529.7 CDI86528.1 - 4.6 6.6 11.2 1.7 8.0 0.8 2.2 2 0 0 2 2 2 0 B-cell receptor-associated protein 31-like DUF4518 PF15008.1 CDI86528.1 - 4.9 6.1 10.4 7.9 5.4 0.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4518) OmpH PF03938.9 CDI86528.1 - 5.7 6.8 32.0 1.6 8.6 11.5 2.1 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Hid1 PF12722.2 CDI86528.1 - 5.8 4.4 14.6 7.3 4.1 10.1 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein U1snRNP70_N PF12220.3 CDI86528.1 - 5.9 7.2 16.3 1.7 9.0 4.5 2.2 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal DUF4604 PF15377.1 CDI86528.1 - 5.9 7.0 19.7 2.3 8.4 4.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4604) DUF1675 PF07897.6 CDI86528.1 - 7 6.4 13.2 9.6 5.9 9.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) T2SM PF04612.7 CDI86528.1 - 7.4 6.3 29.6 0.031 14.0 1.2 2.2 2 0 0 2 2 1 0 Type II secretion system (T2SS), protein M SIT PF15330.1 CDI86528.1 - 9.9 6.3 18.8 0.54 10.4 3.8 2.8 2 1 0 2 2 2 0 SHP2-interacting transmembrane adaptor protein, SIT RAP1 PF07218.6 CDI86529.1 - 0.0048 15.0 5.8 0.0045 15.1 4.0 1.2 1 0 0 1 1 1 1 Rhoptry-associated protein 1 (RAP-1) Hamartin PF04388.7 CDI86529.1 - 0.048 12.3 22.0 0.063 11.9 15.3 1.1 1 0 0 1 1 1 0 Hamartin protein FimP PF09766.4 CDI86529.1 - 0.077 12.0 30.4 0.23 10.5 11.6 2.3 2 0 0 2 2 2 0 Fms-interacting protein TFIIA PF03153.8 CDI86529.1 - 0.3 10.9 45.7 0.41 10.4 31.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Plasmodium_Vir PF05795.6 CDI86529.1 - 0.46 9.6 12.7 0.056 12.6 5.3 1.8 2 0 0 2 2 2 0 Plasmodium vivax Vir protein Med15 PF09606.5 CDI86529.1 - 0.47 8.5 65.0 0.8 7.8 45.1 1.3 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal LpxB PF02684.10 CDI86529.1 - 1.2 7.7 13.0 0.16 10.6 3.3 2.1 2 0 0 2 2 2 0 Lipid-A-disaccharide synthetase Pox_Ag35 PF03286.9 CDI86529.1 - 1.3 8.5 15.7 0.26 10.8 7.8 1.9 2 0 0 2 2 2 0 Pox virus Ag35 surface protein Macoilin PF09726.4 CDI86529.1 - 3.8 5.6 33.2 5.9 5.0 23.0 1.2 1 0 0 1 1 1 0 Transmembrane protein eIF-3_zeta PF05091.7 CDI86529.1 - 4.2 5.8 21.8 2.8 6.4 1.0 2.1 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) FCP1_C PF09309.5 CDI86529.1 - 5.3 6.2 33.0 2.7 7.2 1.1 2.4 2 1 0 2 2 2 0 FCP1, C-terminal DUF4647 PF15504.1 CDI86529.1 - 7.4 5.3 29.4 0.34 9.7 11.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4647) DUF822 PF05687.8 CDI86531.1 - 1 9.6 16.1 1.1 9.5 11.1 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF822) DUF3807 PF12720.2 CDI86531.1 - 2.3 8.3 29.7 2.5 8.2 20.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) Methyltransf_29 PF03141.11 CDI86531.1 - 3.8 5.7 14.4 4.1 5.6 10.0 1.0 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase DUF2361 PF10153.4 CDI86531.1 - 4.2 7.6 27.1 5.4 7.2 18.8 1.2 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2361) PAT1 PF09770.4 CDI86531.1 - 5.3 5.1 51.1 5.7 5.0 35.4 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF2894 PF11445.3 CDI86531.1 - 9.5 6.4 22.6 11 6.2 15.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2894) Utp14 PF04615.8 CDI86532.1 - 1.3 7.1 36.9 1.7 6.7 25.6 1.2 1 0 0 1 1 1 0 Utp14 protein Med15 PF09606.5 CDI86532.1 - 4.6 5.3 122.4 5.2 5.1 84.9 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal PRP1_N PF06424.7 CDI86532.1 - 6.1 7.1 35.9 3.9 7.8 6.2 3.2 2 1 1 3 3 3 0 PRP1 splicing factor, N-terminal CD20 PF04103.10 CDI86532.1 - 9.6 6.1 18.9 0.85 9.5 0.7 3.2 2 1 1 3 3 3 0 CD20-like family SprA-related PF12118.3 CDI86533.1 - 0.0086 15.4 35.8 0.0094 15.3 24.8 1.0 1 0 0 1 1 1 1 SprA-related family PMSI1 PF15322.1 CDI86533.1 - 0.019 14.0 11.0 0.021 13.9 7.6 1.0 1 0 0 1 1 1 0 Protein missing in infertile sperm 1, putative Med13_N PF11597.3 CDI86533.1 - 0.069 11.8 17.0 0.079 11.6 11.8 1.0 1 0 0 1 1 1 0 Mediator complex subunit 13 N-terminal Trp_oprn_chp PF09534.5 CDI86533.1 - 0.079 12.5 5.4 0.092 12.3 3.8 1.1 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) CDC27 PF09507.5 CDI86533.1 - 0.11 11.6 16.4 0.13 11.4 11.4 1.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 PcfK PF14058.1 CDI86533.1 - 0.13 12.4 15.1 0.17 11.9 10.4 1.2 1 0 0 1 1 1 0 PcfK-like protein DUF4192 PF13830.1 CDI86533.1 - 0.14 11.8 9.0 0.17 11.5 6.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4192) CD20 PF04103.10 CDI86533.1 - 0.19 11.6 0.7 0.25 11.2 0.5 1.2 1 0 0 1 1 1 0 CD20-like family MARCKS PF02063.12 CDI86533.1 - 0.26 11.1 15.5 0.28 10.9 10.7 1.0 1 0 0 1 1 1 0 MARCKS family FLO_LFY PF01698.11 CDI86533.1 - 0.3 9.9 16.6 0.31 9.8 11.5 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein Glt_symporter PF03616.9 CDI86533.1 - 0.3 9.5 2.9 0.31 9.4 2.0 1.1 1 0 0 1 1 1 0 Sodium/glutamate symporter Baculo_PP31 PF05311.6 CDI86533.1 - 0.31 10.2 13.9 0.37 10.0 9.6 1.2 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) DUF2217 PF10265.4 CDI86533.1 - 0.33 9.6 8.3 0.37 9.5 5.8 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) SelP_N PF04592.9 CDI86533.1 - 0.43 9.9 12.6 0.49 9.7 8.7 1.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region SRP-alpha_N PF04086.8 CDI86533.1 - 0.45 9.8 16.4 0.51 9.6 11.4 1.0 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Pex14_N PF04695.8 CDI86533.1 - 0.45 10.5 24.6 0.62 10.1 17.1 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Ctr PF04145.10 CDI86533.1 - 0.54 10.3 7.4 0.69 9.9 5.1 1.3 1 0 0 1 1 1 0 Ctr copper transporter family HemX PF04375.9 CDI86533.1 - 0.54 8.7 28.8 0.63 8.5 20.0 1.0 1 0 0 1 1 1 0 HemX Pal1 PF08316.6 CDI86533.1 - 0.57 10.6 8.0 0.75 10.2 5.6 1.2 1 0 0 1 1 1 0 Pal1 cell morphology protein Peptidase_S15 PF02129.13 CDI86533.1 - 0.61 9.4 9.5 0.78 9.1 6.6 1.3 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) DUF4557 PF15101.1 CDI86533.1 - 0.7 9.6 22.8 0.85 9.4 15.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) AIF_C PF14721.1 CDI86533.1 - 0.71 10.1 12.2 0.98 9.6 8.5 1.4 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Med15 PF09606.5 CDI86533.1 - 0.77 7.8 43.8 0.81 7.8 30.4 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal GAGA_bind PF06217.7 CDI86533.1 - 0.8 9.6 13.7 0.87 9.5 9.5 1.0 1 0 0 1 1 1 0 GAGA binding protein-like family PAT1 PF09770.4 CDI86533.1 - 0.81 7.8 33.7 0.92 7.6 23.4 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Serinc PF03348.10 CDI86533.1 - 0.84 8.2 12.6 0.87 8.2 8.7 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) Peptidase_U57 PF05582.7 CDI86533.1 - 0.98 8.3 10.4 1.1 8.1 7.2 1.1 1 0 0 1 1 1 0 YabG peptidase U57 RR_TM4-6 PF06459.7 CDI86533.1 - 1 9.1 16.0 1.1 9.0 11.1 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Rtf2 PF04641.7 CDI86533.1 - 1 8.4 17.7 1.2 8.3 12.3 1.0 1 0 0 1 1 1 0 Rtf2 RING-finger FAM60A PF15396.1 CDI86533.1 - 1 9.0 10.1 1.2 8.8 7.0 1.2 1 0 0 1 1 1 0 Protein Family FAM60A DUF3824 PF12868.2 CDI86533.1 - 1.2 10.0 11.6 1.8 9.4 8.1 1.3 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) DUF1510 PF07423.6 CDI86533.1 - 1.2 8.4 17.2 1.4 8.2 11.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) YABBY PF04690.8 CDI86533.1 - 1.4 9.1 7.9 1.6 8.9 5.5 1.2 1 0 0 1 1 1 0 YABBY protein Raftlin PF15250.1 CDI86533.1 - 1.4 7.3 17.5 1.7 7.1 12.2 1.0 1 0 0 1 1 1 0 Raftlin Lin-8 PF03353.10 CDI86533.1 - 1.5 8.0 16.8 1.6 7.9 11.7 1.0 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist TFIIA PF03153.8 CDI86533.1 - 1.5 8.6 31.0 1.7 8.4 21.5 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4011 PF13195.1 CDI86533.1 - 1.6 8.7 9.0 1.8 8.5 6.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4011) Zip PF02535.17 CDI86533.1 - 1.8 7.4 7.6 2.1 7.2 5.3 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter AAA_23 PF13476.1 CDI86533.1 - 2 8.7 14.2 2.2 8.5 9.9 1.1 1 0 0 1 1 1 0 AAA domain DUF2232 PF09991.4 CDI86533.1 - 2 7.3 4.5 2.3 7.1 3.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) CDK5_activator PF03261.10 CDI86533.1 - 2 7.6 14.6 2.3 7.4 10.1 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein OATP PF03137.15 CDI86533.1 - 2.1 6.3 8.9 2 6.3 6.1 1.2 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family DOR PF14839.1 CDI86533.1 - 2.1 8.0 24.8 2.4 7.8 17.2 1.1 1 0 0 1 1 1 0 DOR family Thioredoxin_4 PF13462.1 CDI86533.1 - 2.2 8.2 12.1 2.6 8.0 8.4 1.0 1 0 0 1 1 1 0 Thioredoxin MelC1 PF06236.6 CDI86533.1 - 2.4 8.1 11.0 3.5 7.6 7.6 1.3 1 0 0 1 1 1 0 Tyrosinase co-factor MelC1 CDC45 PF02724.9 CDI86533.1 - 2.4 6.0 13.7 2.7 5.9 9.5 1.0 1 0 0 1 1 1 0 CDC45-like protein Gti1_Pac2 PF09729.4 CDI86533.1 - 2.5 7.9 9.1 3 7.6 6.3 1.3 1 0 0 1 1 1 0 Gti1/Pac2 family UPF0560 PF10577.4 CDI86533.1 - 2.5 6.2 20.9 2.6 6.1 14.5 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Spc7_N PF15402.1 CDI86533.1 - 2.5 5.9 19.2 3 5.7 13.3 1.0 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 eIF-3_zeta PF05091.7 CDI86533.1 - 2.6 6.5 19.0 2.5 6.5 13.2 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DDHD PF02862.12 CDI86533.1 - 2.6 7.8 15.7 2.8 7.6 10.9 1.1 1 0 0 1 1 1 0 DDHD domain Peptidase_S49_N PF08496.5 CDI86533.1 - 2.9 7.6 12.7 4 7.2 8.8 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal CPSF100_C PF13299.1 CDI86533.1 - 3 7.9 12.1 3.6 7.7 8.4 1.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Herpes_glycop PF01528.11 CDI86533.1 - 3.2 6.3 6.2 3.6 6.2 4.3 1.1 1 0 0 1 1 1 0 Herpesvirus glycoprotein M APG6 PF04111.7 CDI86533.1 - 3.3 6.6 19.7 3.8 6.4 13.6 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 R_equi_Vir PF05526.6 CDI86533.1 - 3.3 7.3 12.6 4.2 6.9 8.7 1.1 1 0 0 1 1 1 0 Rhodococcus equi virulence-associated protein DUF3408 PF11888.3 CDI86533.1 - 3.4 7.6 13.4 5 7.0 9.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) BTV_NS2 PF04514.7 CDI86533.1 - 3.4 6.4 12.3 3.8 6.2 8.5 1.0 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Suf PF05843.9 CDI86533.1 - 3.7 7.1 20.3 4.8 6.8 14.1 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) AUX_IAA PF02309.11 CDI86533.1 - 4.2 7.0 13.6 4.6 6.9 9.5 1.1 1 0 0 1 1 1 0 AUX/IAA family Dicty_REP PF05086.7 CDI86533.1 - 4.5 4.8 14.7 4.7 4.8 10.2 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Maf1 PF09174.5 CDI86533.1 - 4.7 7.0 9.3 5.7 6.7 6.5 1.2 1 0 0 1 1 1 0 Maf1 regulator DUF605 PF04652.11 CDI86533.1 - 4.7 6.5 22.5 5.3 6.3 15.6 1.1 1 0 0 1 1 1 0 Vta1 like NARP1 PF12569.3 CDI86533.1 - 4.8 5.8 19.1 5.8 5.5 13.2 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Herpes_DNAp_acc PF04929.7 CDI86533.1 - 4.8 6.0 12.6 5.4 5.8 8.8 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor DUF4175 PF13779.1 CDI86533.1 - 5.1 4.6 39.7 5.7 4.5 27.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Parvo_coat PF00740.13 CDI86533.1 - 5.6 5.8 17.4 6.2 5.6 12.1 1.0 1 0 0 1 1 1 0 Parvovirus coat protein VP2 DUF2052 PF09747.4 CDI86533.1 - 5.9 6.7 20.0 7.1 6.5 13.8 1.1 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) Ycf1 PF05758.7 CDI86533.1 - 6.4 4.3 15.4 6.9 4.2 10.7 1.0 1 0 0 1 1 1 0 Ycf1 MDFI PF15316.1 CDI86533.1 - 6.5 6.7 12.1 7.6 6.4 8.4 1.2 1 0 0 1 1 1 0 MyoD family inhibitor Hid1 PF12722.2 CDI86533.1 - 6.9 4.2 15.1 7.2 4.1 10.5 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SAPS PF04499.10 CDI86533.1 - 7.3 5.1 15.5 7.4 5.0 10.7 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Presenilin PF01080.12 CDI86533.1 - 7.6 5.2 14.8 8 5.1 10.3 1.0 1 0 0 1 1 1 0 Presenilin Cellulose_synt PF03552.9 CDI86533.1 - 7.6 4.6 7.0 8 4.6 4.8 1.0 1 0 0 1 1 1 0 Cellulose synthase DUF3123 PF11321.3 CDI86533.1 - 7.6 6.8 8.1 8.2 6.7 5.3 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3123) CKAP2_C PF15297.1 CDI86533.1 - 7.7 5.2 18.6 9.1 4.9 12.9 1.0 1 0 0 1 1 1 0 Cytoskeleton-associated protein 2 C-terminus DUF4544 PF15077.1 CDI86533.1 - 8.3 5.8 7.8 8.2 5.8 5.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4544) Gag_spuma PF03276.9 CDI86533.1 - 9.1 4.4 32.6 10 4.3 22.6 1.0 1 0 0 1 1 1 0 Spumavirus gag protein His_Phos_2 PF00328.17 CDI86533.1 - 9.3 5.4 14.9 11 5.1 10.3 1.0 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 2) CMV_1a PF12467.3 CDI86533.1 - 9.7 6.5 13.8 11 6.3 9.5 1.1 1 0 0 1 1 1 0 Cucumber mosaic virus 1a protein family NPR3 PF03666.8 CDI86533.1 - 10 4.5 14.7 11 4.4 10.2 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Ycf1 PF05758.7 CDI86534.1 - 0.0058 14.4 9.7 0.0058 14.4 6.7 1.0 1 0 0 1 1 1 1 Ycf1 Hid1 PF12722.2 CDI86534.1 - 0.038 11.6 14.0 0.04 11.6 9.7 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SprA-related PF12118.3 CDI86534.1 - 0.077 12.3 36.6 0.088 12.1 25.3 1.1 1 0 0 1 1 1 0 SprA-related family RR_TM4-6 PF06459.7 CDI86534.1 - 0.12 12.2 17.3 0.14 12.0 12.0 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DDHD PF02862.12 CDI86534.1 - 0.22 11.2 14.5 0.28 10.9 10.1 1.1 1 0 0 1 1 1 0 DDHD domain CDC45 PF02724.9 CDI86534.1 - 0.29 9.1 16.3 0.34 8.8 11.3 1.0 1 0 0 1 1 1 0 CDC45-like protein SAGA-Tad1 PF12767.2 CDI86534.1 - 0.43 10.2 18.6 0.5 9.9 12.9 1.1 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit DUF2201_N PF13203.1 CDI86534.1 - 0.53 9.4 20.4 0.64 9.1 14.1 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain Med15 PF09606.5 CDI86534.1 - 0.6 8.2 54.4 0.65 8.1 37.7 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal NARP1 PF12569.3 CDI86534.1 - 0.61 8.7 14.3 0.68 8.6 9.9 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Dehalogenase PF13486.1 CDI86534.1 - 0.8 9.1 7.5 1 8.7 5.2 1.1 1 0 0 1 1 1 0 Reductive dehalogenase subunit Trypan_PARP PF05887.6 CDI86534.1 - 0.96 9.2 8.1 1.4 8.7 5.6 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DUF4045 PF13254.1 CDI86534.1 - 1.3 8.2 17.4 1.5 8.0 12.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) AUX_IAA PF02309.11 CDI86534.1 - 1.5 8.5 11.1 1.8 8.2 7.7 1.2 1 0 0 1 1 1 0 AUX/IAA family TFIIA PF03153.8 CDI86534.1 - 1.6 8.5 34.6 1.8 8.3 24.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SPX PF03105.14 CDI86534.1 - 1.9 8.2 16.0 2.3 7.9 11.1 1.1 1 0 0 1 1 1 0 SPX domain PAT1 PF09770.4 CDI86534.1 - 2.4 6.3 46.8 2.7 6.1 32.4 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 GAGA_bind PF06217.7 CDI86534.1 - 2.5 7.9 15.5 2.8 7.8 10.8 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family Tim54 PF11711.3 CDI86534.1 - 2.7 6.4 12.6 3.2 6.2 8.7 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DUF605 PF04652.11 CDI86534.1 - 3.2 7.0 27.9 3.7 6.8 19.3 1.1 1 0 0 1 1 1 0 Vta1 like DHHW PF14286.1 CDI86534.1 - 3.7 6.7 14.4 4.5 6.4 10.0 1.1 1 0 0 1 1 1 0 DHHW protein Paramyxo_ncap PF00973.14 CDI86534.1 - 4.4 5.8 13.2 5 5.7 9.2 1.0 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Asp-B-Hydro_N PF05279.6 CDI86534.1 - 4.9 6.9 15.3 5.9 6.6 10.6 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region DUF1510 PF07423.6 CDI86534.1 - 5.3 6.3 21.7 7.1 5.9 15.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Gti1_Pac2 PF09729.4 CDI86534.1 - 8.1 6.2 9.6 12 5.6 6.7 1.4 1 0 0 1 1 1 0 Gti1/Pac2 family Lin-8 PF03353.10 CDI86534.1 - 8.5 5.5 20.8 9.8 5.3 14.5 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist SID-1_RNA_chan PF13965.1 CDI86534.1 - 8.7 4.3 9.1 9.2 4.3 6.3 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 OmpH PF03938.9 CDI86535.1 - 0.00016 21.6 12.1 0.00016 21.6 8.4 7.5 5 3 0 6 6 6 1 Outer membrane protein (OmpH-like) PIG-U PF06728.8 CDI86535.1 - 0.11 11.2 2.6 0.21 10.3 1.8 1.4 1 0 0 1 1 1 0 GPI transamidase subunit PIG-U CAF1 PF04857.15 CDI86536.1 - 2e-28 99.4 13.1 3.1e-27 95.5 9.1 3.2 1 1 0 1 1 1 1 CAF1 family ribonuclease MIP-T3 PF10243.4 CDI86536.1 - 6e-05 21.7 39.4 6e-05 21.7 27.3 1.8 2 0 0 2 2 2 1 Microtubule-binding protein MIP-T3 DUF936 PF06075.7 CDI86536.1 - 0.3 9.9 35.4 0.46 9.3 24.6 1.3 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) FB_lectin PF07367.6 CDI86536.1 - 6.8 6.2 9.5 22 4.6 6.6 1.9 1 1 0 1 1 1 0 Fungal fruit body lectin DUF1970 PF09301.5 CDI86537.1 - 0.18 11.8 1.1 0.43 10.6 0.8 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1970) Ribosomal_60s PF00428.14 CDI86538.1 - 0.18 12.2 9.5 0.24 11.7 6.6 1.2 1 0 0 1 1 1 0 60s Acidic ribosomal protein Zip PF02535.17 CDI86538.1 - 2.8 6.8 17.4 3.4 6.5 12.0 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter DUF1510 PF07423.6 CDI86538.1 - 5.1 6.4 26.3 5.8 6.2 18.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Presenilin PF01080.12 CDI86538.1 - 8 5.1 22.0 8.9 5.0 15.2 1.0 1 0 0 1 1 1 0 Presenilin DUF1510 PF07423.6 CDI86540.1 - 3.8e-07 29.7 12.3 4.3e-07 29.5 8.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) SpoIIIAH PF12685.2 CDI86540.1 - 2.7e-06 27.0 5.9 3.3e-06 26.7 4.1 1.2 1 0 0 1 1 1 1 SpoIIIAH-like protein DUF4131 PF13567.1 CDI86540.1 - 0.00021 20.7 2.0 0.00024 20.5 1.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4131) TRAP_alpha PF03896.11 CDI86540.1 - 0.00021 20.3 3.7 0.00026 20.1 2.6 1.2 1 0 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit DUF1183 PF06682.7 CDI86540.1 - 0.00031 20.4 4.1 0.00038 20.1 2.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1183) Ycf1 PF05758.7 CDI86540.1 - 0.00045 18.0 18.4 0.0005 17.9 12.8 1.0 1 0 0 1 1 1 1 Ycf1 SID-1_RNA_chan PF13965.1 CDI86540.1 - 0.00073 17.8 11.8 0.0008 17.7 8.2 1.0 1 0 0 1 1 1 1 dsRNA-gated channel SID-1 Neur_chan_memb PF02932.11 CDI86540.1 - 0.0016 18.3 11.7 0.002 18.0 8.1 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Mem_trans PF03547.13 CDI86540.1 - 0.0018 16.6 11.5 0.0021 16.4 8.0 1.0 1 0 0 1 1 1 1 Membrane transport protein Gastrin PF00918.12 CDI86540.1 - 0.0025 18.6 23.0 0.003 18.3 16.0 1.2 1 0 0 1 1 1 1 Gastrin/cholecystokinin family FHIPEP PF00771.15 CDI86540.1 - 0.0058 15.0 13.7 0.0069 14.7 9.5 1.1 1 0 0 1 1 1 1 FHIPEP family Innexin PF00876.13 CDI86540.1 - 0.0094 15.0 3.7 0.012 14.7 2.6 1.2 1 0 0 1 1 1 1 Innexin Ion_trans PF00520.26 CDI86540.1 - 0.0097 15.1 0.0 0.0097 15.1 0.0 1.1 1 0 0 1 1 1 1 Ion transport protein Choline_transpo PF04515.7 CDI86540.1 - 0.011 14.5 0.0 0.011 14.5 0.0 1.2 1 0 0 1 1 1 0 Plasma-membrane choline transporter Pex24p PF06398.6 CDI86540.1 - 0.012 14.4 7.1 0.022 13.5 5.0 1.6 1 1 0 1 1 1 0 Integral peroxisomal membrane peroxin DUF2500 PF10694.4 CDI86540.1 - 0.012 15.5 5.7 0.012 15.5 4.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2500) DUF3260 PF11658.3 CDI86540.1 - 0.015 13.5 14.2 0.016 13.4 9.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3260) Tetraspannin PF00335.15 CDI86540.1 - 0.015 14.5 9.8 0.026 13.8 6.8 1.4 1 1 0 1 1 1 0 Tetraspanin family Herpes_gE PF02480.11 CDI86540.1 - 0.016 13.4 0.0 0.022 13.0 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Protocadherin PF08374.6 CDI86540.1 - 0.021 14.4 12.3 0.032 13.8 8.6 1.3 1 0 0 1 1 1 0 Protocadherin PRA1 PF03208.14 CDI86540.1 - 0.028 13.7 2.7 0.033 13.5 1.9 1.4 1 1 0 1 1 1 0 PRA1 family protein Neur PF00064.13 CDI86540.1 - 0.032 12.3 4.5 0.035 12.2 3.1 1.1 1 0 0 1 1 1 0 Neuraminidase MacB_PCD PF12704.2 CDI86540.1 - 0.05 13.1 0.0 0.059 12.9 0.0 1.1 1 0 0 1 1 1 0 MacB-like periplasmic core domain Sarcoglycan_2 PF05510.8 CDI86540.1 - 0.056 11.7 9.8 0.065 11.5 6.8 1.1 1 0 0 1 1 1 0 Sarcoglycan alpha/epsilon IncA PF04156.9 CDI86540.1 - 0.059 12.9 33.4 0.09 12.3 23.2 1.4 1 1 0 1 1 1 0 IncA protein DUF4097 PF13349.1 CDI86540.1 - 0.059 12.9 0.1 0.059 12.9 0.1 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4097) Herpes_LMP1 PF05297.6 CDI86540.1 - 0.075 11.9 1.2 0.084 11.7 0.9 1.3 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) DUF4446 PF14584.1 CDI86540.1 - 0.08 12.7 18.3 0.13 12.1 12.7 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF4446) DUF4636 PF15468.1 CDI86540.1 - 0.085 12.2 9.0 0.13 11.7 6.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4636) Ni_hydr_CYTB PF01292.15 CDI86540.1 - 0.12 11.7 5.8 0.26 10.6 4.0 1.8 1 1 0 1 1 1 0 Prokaryotic cytochrome b561 DUF2569 PF10754.4 CDI86540.1 - 0.13 12.4 2.2 0.18 12.0 1.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2569) DUF4330 PF14221.1 CDI86540.1 - 0.13 12.1 3.8 0.15 11.9 2.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4330) NicO PF03824.11 CDI86540.1 - 0.14 11.4 1.8 0.17 11.1 1.3 1.2 1 0 0 1 1 1 0 High-affinity nickel-transport protein Sre PF03125.13 CDI86540.1 - 0.14 11.0 6.0 0.17 10.7 4.1 1.1 1 0 0 1 1 1 0 C. elegans Sre G protein-coupled chemoreceptor Reticulon PF02453.12 CDI86540.1 - 0.19 11.3 3.1 0.16 11.5 1.4 1.4 1 1 0 1 1 1 0 Reticulon FAM176 PF14851.1 CDI86540.1 - 0.21 11.2 16.7 0.16 11.6 10.0 1.8 1 1 1 2 2 2 0 FAM176 family DUF1312 PF07009.6 CDI86540.1 - 0.24 11.2 5.1 0.39 10.5 3.5 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1312) ABC2_membrane_2 PF12679.2 CDI86540.1 - 0.32 9.8 10.2 0.46 9.3 7.0 1.5 1 1 0 1 1 1 0 ABC-2 family transporter protein Otopetrin PF03189.8 CDI86540.1 - 0.33 9.9 10.7 0.46 9.4 7.4 1.3 1 0 0 1 1 1 0 Otopetrin YfhO PF09586.5 CDI86540.1 - 0.33 8.9 17.5 0.075 11.0 9.8 1.6 1 1 0 1 1 1 0 Bacterial membrane protein YfhO MAPEG PF01124.13 CDI86540.1 - 0.35 10.4 6.7 0.59 9.7 4.6 1.7 1 1 0 1 1 1 0 MAPEG family FliP PF00813.15 CDI86540.1 - 0.36 10.5 15.4 0.44 10.2 10.7 1.1 1 0 0 1 1 1 0 FliP family ABC_membrane PF00664.18 CDI86540.1 - 0.41 10.0 5.6 0.56 9.5 3.7 1.5 1 1 0 1 1 1 0 ABC transporter transmembrane region K_trans PF02705.11 CDI86540.1 - 0.44 8.8 8.8 0.54 8.5 6.1 1.1 1 0 0 1 1 1 0 K+ potassium transporter Chordopox_A33R PF05966.7 CDI86540.1 - 0.48 9.1 7.4 0.72 8.6 5.1 1.3 1 1 0 1 1 1 0 Chordopoxvirus A33R protein RskA PF10099.4 CDI86540.1 - 0.57 9.8 6.1 1.4 8.6 4.3 1.7 1 1 0 1 1 1 0 Anti-sigma-K factor rskA DUF4220 PF13968.1 CDI86540.1 - 0.9 8.5 10.1 1.1 8.2 7.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4220) DUF3357 PF11837.3 CDI86540.1 - 1.1 9.1 16.5 0.063 13.1 5.2 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF3357) TAS2R PF05296.8 CDI86540.1 - 1.3 7.8 9.1 1.7 7.4 6.3 1.4 1 1 0 1 1 1 0 Mammalian taste receptor protein (TAS2R) PIG-P PF08510.7 CDI86540.1 - 1.3 8.6 11.3 7.3 6.2 7.8 2.0 1 1 0 1 1 1 0 PIG-P DUF4010 PF13194.1 CDI86540.1 - 1.3 8.2 5.7 0.64 9.2 2.6 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4010) Patched PF02460.13 CDI86540.1 - 1.4 6.7 7.3 1.5 6.6 5.0 1.1 1 0 0 1 1 1 0 Patched family HemY_N PF07219.8 CDI86540.1 - 1.7 8.2 8.8 1.7 8.2 5.6 1.5 1 1 0 1 1 1 0 HemY protein N-terminus Folate_carrier PF01770.13 CDI86540.1 - 1.8 7.0 17.1 1.8 6.9 11.3 1.5 1 1 0 1 1 1 0 Reduced folate carrier DUF3530 PF12048.3 CDI86540.1 - 1.8 7.4 26.2 10 4.9 18.2 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3530) DUF2448 PF10476.4 CDI86540.1 - 2 7.9 5.6 2.4 7.6 3.9 1.1 1 0 0 1 1 1 0 Protein of unknown function C-terminus (DUF2448) DUF2370 PF10176.4 CDI86540.1 - 2.1 7.6 14.0 2.7 7.2 9.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) DUF3450 PF11932.3 CDI86540.1 - 2.2 7.4 35.7 2.5 7.2 24.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF2208 PF09973.4 CDI86540.1 - 2.3 7.4 8.5 2.3 7.4 5.5 1.4 1 1 0 1 1 1 0 Predicted membrane protein (DUF2208) TMEM51 PF15345.1 CDI86540.1 - 2.5 7.7 28.4 4.5 6.8 19.7 1.5 1 1 0 1 1 1 0 Transmembrane protein 51 TRP PF06011.7 CDI86540.1 - 3 6.3 11.3 8 4.9 7.7 1.8 1 1 0 1 1 1 0 Transient receptor potential (TRP) ion channel HCO3_cotransp PF00955.16 CDI86540.1 - 3.2 6.2 9.3 3.6 6.1 6.5 1.0 1 0 0 1 1 1 0 HCO3- transporter family DUF2140 PF09911.4 CDI86540.1 - 3.3 6.8 18.5 25 3.9 12.8 2.0 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2140) Cytochrom_B_N PF00033.14 CDI86540.1 - 3.3 7.0 12.4 18 4.5 8.6 2.2 1 1 0 1 1 1 0 Cytochrome b(N-terminal)/b6/petB Cytochrom_B_N_2 PF13631.1 CDI86540.1 - 3.4 7.4 7.2 7.7 6.2 5.0 1.8 1 1 0 1 1 1 0 Cytochrome b(N-terminal)/b6/petB Ctr PF04145.10 CDI86540.1 - 3.5 7.6 17.4 13 5.8 12.0 1.8 1 1 0 1 1 1 0 Ctr copper transporter family CLN3 PF02487.12 CDI86540.1 - 3.6 6.2 5.3 4.1 6.0 3.7 1.2 1 0 0 1 1 1 0 CLN3 protein DUF2227 PF09988.4 CDI86540.1 - 3.7 7.1 7.8 6.1 6.4 5.4 1.5 1 1 0 1 1 1 0 Uncharacterized metal-binding protein (DUF2227) RP-C_C PF11800.3 CDI86540.1 - 4.7 6.8 19.1 6 6.5 13.2 1.2 1 0 0 1 1 1 0 Replication protein C C-terminal region Bap31 PF05529.7 CDI86540.1 - 7.3 5.9 32.4 8.3 5.8 22.0 1.4 1 1 0 1 1 1 0 B-cell receptor-associated protein 31-like DUF913 PF06025.7 CDI86540.1 - 9 4.9 14.0 10 4.7 9.7 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DUF4512 PF14975.1 CDI86540.1 - 9.1 7.1 17.2 25 5.7 11.9 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4512) Peptidase_M56 PF05569.6 CDI86540.1 - 9.2 5.1 9.7 1.4 7.8 3.0 1.6 1 1 0 1 1 1 0 BlaR1 peptidase M56 DUF1345 PF07077.6 CDI86540.1 - 9.6 5.6 7.0 0.59 9.6 0.7 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1345) CD20 PF04103.10 CDI86541.1 - 4.1e-05 23.5 0.5 4.1e-05 23.5 0.4 3.7 2 1 0 2 2 2 1 CD20-like family IncA PF04156.9 CDI86541.1 - 0.00013 21.5 18.3 0.00013 21.5 12.7 4.5 3 1 0 3 3 3 1 IncA protein DUF2029 PF09594.5 CDI86544.1 - 0.0096 15.4 5.1 0.053 13.0 3.2 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2029) Apc15p PF05841.6 CDI86544.1 - 0.016 15.9 7.0 0.016 15.9 4.9 7.4 4 3 2 6 6 6 0 Apc15p protein Ribosomal_S2 PF00318.15 CDI86546.1 - 2.6 7.2 6.8 2.7 7.1 4.7 1.1 1 0 0 1 1 1 0 Ribosomal protein S2 Allexi_40kDa PF05549.6 CDI86546.1 - 3.2 6.9 14.6 3.7 6.7 10.1 1.0 1 0 0 1 1 1 0 Allexivirus 40kDa protein Gly-zipper_OmpA PF13436.1 CDI86548.1 - 0.00024 20.7 10.3 0.00024 20.7 7.2 2.2 2 0 0 2 2 2 1 Glycine-zipper containing OmpA-like membrane domain Activator_LAG-3 PF11498.3 CDI86548.1 - 0.0038 16.0 15.0 0.0039 16.0 10.4 1.1 1 0 0 1 1 1 1 Transcriptional activator LAG-3 SR-25 PF10500.4 CDI86548.1 - 0.008 15.6 7.5 0.0088 15.5 5.2 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein PRTP PF01366.13 CDI86548.1 - 0.022 12.7 4.8 0.024 12.6 3.3 1.0 1 0 0 1 1 1 0 Herpesvirus processing and transport protein ATG16 PF08614.6 CDI86548.1 - 0.039 13.7 11.5 0.051 13.4 8.0 1.1 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Nha1_C PF08619.5 CDI86548.1 - 0.043 13.1 8.2 0.05 12.8 5.7 1.1 1 0 0 1 1 1 0 Alkali metal cation/H+ antiporter Nha1 C terminus U79_P34 PF03064.11 CDI86548.1 - 0.084 12.3 8.7 0.098 12.1 6.0 1.2 1 0 0 1 1 1 0 HSV U79 / HCMV P34 BTV_NS2 PF04514.7 CDI86548.1 - 0.087 11.6 3.7 0.097 11.5 2.5 1.0 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 FimP PF09766.4 CDI86548.1 - 0.12 11.4 8.3 0.13 11.3 5.8 1.1 1 0 0 1 1 1 0 Fms-interacting protein PBP_sp32 PF07222.7 CDI86548.1 - 0.12 11.5 10.2 0.15 11.2 7.1 1.2 1 0 0 1 1 1 0 Proacrosin binding protein sp32 DUF4207 PF13904.1 CDI86548.1 - 0.13 11.5 18.0 0.16 11.3 12.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4207) Neur_chan_memb PF02932.11 CDI86548.1 - 0.13 12.0 1.0 0.15 11.9 0.7 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region FAM176 PF14851.1 CDI86548.1 - 0.19 11.4 2.2 0.26 10.9 1.5 1.2 1 0 0 1 1 1 0 FAM176 family DUF572 PF04502.8 CDI86548.1 - 0.25 10.5 8.3 0.28 10.3 5.8 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF572) Suf PF05843.9 CDI86548.1 - 0.27 10.9 8.2 0.3 10.7 5.7 1.0 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Herpes_UL87 PF03043.9 CDI86548.1 - 0.31 9.3 4.5 0.38 9.0 3.1 1.0 1 0 0 1 1 1 0 Herpesvirus UL87 family Peptidase_S15 PF02129.13 CDI86548.1 - 0.32 10.3 6.2 0.38 10.1 4.3 1.1 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Serinc PF03348.10 CDI86548.1 - 0.35 9.5 3.9 0.4 9.3 2.7 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) MRP-S26 PF14943.1 CDI86548.1 - 0.36 10.3 10.1 0.41 10.1 7.0 1.1 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 DUF2215 PF10225.4 CDI86548.1 - 0.37 10.1 1.2 0.43 9.9 0.9 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) FLO_LFY PF01698.11 CDI86548.1 - 0.41 9.4 9.8 0.48 9.2 6.8 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein Rpp20 PF12328.3 CDI86548.1 - 0.41 10.2 8.1 0.6 9.7 5.6 1.2 1 0 0 1 1 1 0 Rpp20 subunit of nuclear RNase MRP and P Spt20 PF12090.3 CDI86548.1 - 0.49 9.7 5.2 0.52 9.6 3.6 1.1 1 0 0 1 1 1 0 Spt20 family DDHD PF02862.12 CDI86548.1 - 0.55 9.9 4.0 0.59 9.8 2.8 1.1 1 0 0 1 1 1 0 DDHD domain eIF-3_zeta PF05091.7 CDI86548.1 - 0.67 8.5 8.7 0.7 8.4 6.1 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Ycf1 PF05758.7 CDI86548.1 - 0.93 7.1 5.5 1.1 6.9 3.8 1.0 1 0 0 1 1 1 0 Ycf1 Peptidase_S49_N PF08496.5 CDI86548.1 - 0.93 9.2 8.0 1.2 8.9 5.6 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal HAUS6_N PF14661.1 CDI86548.1 - 0.95 8.7 9.2 1.1 8.5 6.4 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus FemAB PF02388.11 CDI86548.1 - 1.1 7.8 8.4 1.3 7.5 5.8 1.1 1 0 0 1 1 1 0 FemAB family Sec62 PF03839.11 CDI86548.1 - 1.2 8.4 4.2 1.5 8.1 2.9 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 UPF0560 PF10577.4 CDI86548.1 - 1.7 6.8 7.5 1.7 6.7 5.2 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 DUF2076 PF09849.4 CDI86548.1 - 1.8 8.5 26.8 2.2 8.2 18.3 1.4 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) DUF1183 PF06682.7 CDI86548.1 - 2.3 7.7 13.0 2.4 7.6 9.0 1.2 1 1 0 1 1 1 0 Protein of unknown function (DUF1183) DUF4231 PF14015.1 CDI86548.1 - 2.5 8.1 7.1 0.55 10.2 2.3 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF4231) RR_TM4-6 PF06459.7 CDI86548.1 - 2.7 7.8 8.5 3.1 7.6 5.9 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Herpes_U34 PF04541.8 CDI86548.1 - 2.8 6.7 6.4 4.1 6.2 4.4 1.2 1 0 0 1 1 1 0 Herpesvirus virion protein U34 CBP4 PF07960.6 CDI86548.1 - 2.9 7.5 13.6 3.8 7.1 9.4 1.2 1 0 0 1 1 1 0 CBP4 Pal1 PF08316.6 CDI86548.1 - 3.1 8.2 7.4 4 7.8 5.1 1.1 1 0 0 1 1 1 0 Pal1 cell morphology protein Shadoo PF14999.1 CDI86548.1 - 3.5 7.4 26.5 3.3 7.5 6.6 2.3 2 0 0 2 2 2 0 Shadow of prion protein, neuroprotective MCR_alpha PF02249.12 CDI86548.1 - 4 7.4 10.4 9.7 6.2 0.3 2.3 2 0 0 2 2 2 0 Methyl-coenzyme M reductase alpha subunit, C-terminal domain GRP PF07172.6 CDI86548.1 - 4.7 7.7 8.8 5.9 7.4 3.3 2.2 2 0 0 2 2 2 0 Glycine rich protein family Baculo_PP31 PF05311.6 CDI86548.1 - 5.3 6.2 8.3 6.4 5.9 5.8 1.1 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) DUF2149 PF09919.4 CDI86548.1 - 6.7 6.8 6.4 11 6.2 4.5 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2149) Gly_rich PF12810.2 CDI86548.1 - 9.4 5.7 11.2 13 5.3 7.8 1.1 1 0 0 1 1 1 0 Glycine rich protein Sigma70_ner PF04546.8 CDI86549.1 - 0.0045 16.6 12.8 0.0056 16.3 8.8 1.1 1 0 0 1 1 1 1 Sigma-70, non-essential region CENP-B_dimeris PF09026.5 CDI86549.1 - 0.084 13.1 9.5 0.14 12.3 6.6 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Daxx PF03344.10 CDI86549.1 - 0.17 10.3 17.4 0.19 10.1 12.1 1.0 1 0 0 1 1 1 0 Daxx Family Nucleoplasmin PF03066.10 CDI86549.1 - 1.9 7.9 10.8 0.055 12.9 3.1 1.7 2 0 0 2 2 2 0 Nucleoplasmin CDC45 PF02724.9 CDI86549.1 - 2.4 6.0 10.5 2.7 5.9 7.3 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF1168 PF06658.7 CDI86549.1 - 2.6 7.5 17.5 0.094 12.2 4.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1168) RNA_pol_3_Rpc31 PF11705.3 CDI86549.1 - 5.3 6.9 14.3 1.8 8.4 6.4 2.0 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 Myc_N PF01056.13 CDI86549.1 - 7.4 5.6 9.4 0.14 11.3 2.0 1.6 2 0 0 2 2 2 0 Myc amino-terminal region Pex14_N PF04695.8 CDI86549.1 - 7.4 6.6 13.0 0.81 9.7 0.1 2.2 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF2457 PF10446.4 CDI86549.1 - 9.2 4.8 14.0 0.13 10.9 4.8 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) AF1Q PF15017.1 CDI86549.1 - 9.6 6.1 12.5 0.53 10.2 3.8 2.1 2 0 0 2 2 2 0 Drug resistance and apoptosis regulator Nol1_Nop2_Fmu PF01189.12 CDI86550.1 - 1.9e-05 24.1 1.4 3.8e-05 23.2 1.0 1.4 1 0 0 1 1 1 1 NOL1/NOP2/sun family Peptidase_C58 PF03543.9 CDI86550.1 - 1.1 8.6 10.4 2 7.8 7.2 1.3 1 0 0 1 1 1 0 Yersinia/Haemophilus virulence surface antigen PSK PF06404.7 CDI86550.1 - 6.6 7.5 8.8 1.1 10.0 0.6 3.3 3 0 0 3 3 3 0 Phytosulfokine precursor protein (PSK) Gaa1 PF04114.9 CDI86552.1 - 0.3 9.7 0.0 20 3.7 0.0 2.1 2 0 0 2 2 2 0 Gaa1-like, GPI transamidase component DUF2254 PF10011.4 CDI86553.1 - 0.14 10.5 0.3 0.21 10.0 0.2 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2254) Methyltransf_16 PF10294.4 CDI86555.1 - 3.2e-05 23.4 0.0 5.7e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 CDI86555.1 - 0.0013 19.2 0.0 0.0041 17.6 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain RRM_1 PF00076.17 CDI86556.1 - 4e-07 29.5 0.0 6.3e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CDI86556.1 - 1.1e-05 25.2 0.0 2.1e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CDI86556.1 - 0.012 15.4 0.0 0.033 14.0 0.0 1.6 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Lactamase_B_2 PF12706.2 CDI86557.1 - 2.1e-15 56.7 0.0 4e-11 42.8 0.0 3.4 2 1 0 2 2 2 2 Beta-lactamase superfamily domain Lactamase_B PF00753.22 CDI86557.1 - 3.6e-07 30.0 0.1 0.0006 19.5 0.1 2.6 2 0 0 2 2 2 2 Metallo-beta-lactamase superfamily AKNA PF12443.3 CDI86559.1 - 0.083 12.9 2.7 0.35 10.9 0.9 2.3 2 0 0 2 2 2 0 AT-hook-containing transcription factor RNA_pol_Rpb2_6 PF00562.23 CDI86560.1 - 3.2e-104 348.7 0.0 5.4e-104 348.0 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 CDI86560.1 - 5.3e-25 87.5 0.0 8.5e-25 86.8 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_7 PF04560.15 CDI86560.1 - 2.9e-18 65.9 0.0 5.9e-18 64.9 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_3 PF04565.11 CDI86560.1 - 1.9e-12 46.7 0.0 4.3e-12 45.6 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 AAA_23 PF13476.1 CDI86562.1 - 0.071 13.4 27.6 0.093 13.0 19.2 1.2 1 0 0 1 1 1 0 AAA domain RAP1 PF07218.6 CDI86562.1 - 1.8 6.5 20.5 2.1 6.3 14.2 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Macoilin PF09726.4 CDI86562.1 - 4.1 5.5 46.9 4.9 5.3 32.5 1.0 1 0 0 1 1 1 0 Transmembrane protein Usp PF00582.21 CDI86563.1 - 0.092 12.9 2.5 0.1 12.8 1.7 1.1 1 0 0 1 1 1 0 Universal stress protein family GRP PF07172.6 CDI86563.1 - 0.11 12.9 2.7 0.14 12.6 1.9 1.2 1 0 0 1 1 1 0 Glycine rich protein family AFT PF08731.6 CDI86563.1 - 0.23 11.6 5.1 0.26 11.4 3.6 1.0 1 0 0 1 1 1 0 Transcription factor AFT DUF3371 PF11851.3 CDI86563.1 - 0.24 12.0 16.5 0.29 11.8 11.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3371) TPP_enzyme_N PF02776.13 CDI86563.1 - 0.29 10.6 1.7 0.34 10.3 1.2 1.2 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain PH_4 PF15404.1 CDI86563.1 - 0.34 10.4 7.9 0.37 10.3 5.5 1.0 1 0 0 1 1 1 0 Pleckstrin homology domain FimP PF09766.4 CDI86563.1 - 0.59 9.1 20.8 0.62 9.0 14.4 1.0 1 0 0 1 1 1 0 Fms-interacting protein FAM176 PF14851.1 CDI86563.1 - 0.59 9.8 5.7 0.74 9.4 4.0 1.1 1 0 0 1 1 1 0 FAM176 family Activator_LAG-3 PF11498.3 CDI86563.1 - 1 8.0 39.8 1 8.0 27.6 1.0 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Conotoxin PF02950.12 CDI86563.1 - 1.1 10.1 7.9 1.9 9.3 5.5 1.4 1 1 0 1 1 1 0 Conotoxin DUF1764 PF08576.5 CDI86563.1 - 1.1 10.0 12.8 1.2 9.9 8.9 1.1 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) Pex14_N PF04695.8 CDI86563.1 - 1.4 8.9 13.2 1.5 8.8 9.2 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region PAT1 PF09770.4 CDI86563.1 - 1.4 7.0 23.2 1.3 7.1 16.1 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Slu7 PF11708.3 CDI86563.1 - 1.5 8.4 15.4 1.7 8.3 10.6 1.1 1 0 0 1 1 1 0 Pre-mRNA splicing Prp18-interacting factor TMEM51 PF15345.1 CDI86563.1 - 1.8 8.2 12.9 2 8.0 9.0 1.1 1 0 0 1 1 1 0 Transmembrane protein 51 AIF_C PF14721.1 CDI86563.1 - 1.9 8.7 10.5 2.1 8.6 7.3 1.1 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term ARF7EP_C PF14949.1 CDI86563.1 - 1.9 8.9 8.9 2.2 8.7 6.2 1.1 1 0 0 1 1 1 0 ARF7 effector protein C-terminus Dala_Dala_lig_N PF01820.16 CDI86563.1 - 2.1 8.6 6.6 2 8.7 4.6 1.1 1 0 0 1 1 1 0 D-ala D-ala ligase N-terminus BRF1 PF07741.8 CDI86563.1 - 2.1 8.6 12.9 2.5 8.3 9.0 1.2 1 0 0 1 1 1 0 Brf1-like TBP-binding domain Neur_chan_memb PF02932.11 CDI86563.1 - 2.3 8.0 6.0 2.6 7.8 4.2 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Phage_int_SAM_5 PF13102.1 CDI86563.1 - 2.4 8.1 10.3 2.8 7.9 7.2 1.1 1 0 0 1 1 1 0 Phage integrase SAM-like domain Herpes_DNAp_acc PF04929.7 CDI86563.1 - 2.4 7.0 7.4 2.3 7.0 5.2 1.0 1 0 0 1 1 1 0 Herpes DNA replication accessory factor RED_N PF07808.8 CDI86563.1 - 2.9 7.0 19.1 3.4 6.8 13.2 1.1 1 0 0 1 1 1 0 RED-like protein N-terminal region DDRGK PF09756.4 CDI86563.1 - 2.9 7.2 20.0 3.3 7.0 13.9 1.1 1 0 0 1 1 1 0 DDRGK domain ATAD4 PF15321.1 CDI86563.1 - 3.2 8.8 10.3 3.9 8.5 7.1 1.2 1 0 0 1 1 1 0 ATPase family AAA domain containing 4 DUF3408 PF11888.3 CDI86563.1 - 3.2 7.6 11.6 3.5 7.5 8.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) DUF2215 PF10225.4 CDI86563.1 - 3.7 6.9 8.0 3.6 6.9 5.6 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) HCV_NS5a_C PF12941.2 CDI86563.1 - 4.1 6.8 5.5 4.6 6.7 3.8 1.0 1 0 0 1 1 1 0 HCV NS5a protein C-terminal region FLO_LFY PF01698.11 CDI86563.1 - 4.5 6.0 11.5 4.8 5.9 8.0 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein DUF3260 PF11658.3 CDI86563.1 - 4.6 5.2 9.3 4.9 5.1 6.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3260) FAM60A PF15396.1 CDI86563.1 - 4.8 6.8 7.3 4.5 6.9 5.1 1.1 1 0 0 1 1 1 0 Protein Family FAM60A Pex16 PF08610.5 CDI86563.1 - 4.9 6.0 9.5 5.1 5.9 6.6 1.0 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) Bud13 PF09736.4 CDI86563.1 - 4.9 7.3 18.0 5.2 7.3 12.4 1.1 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex Peroxin-13_N PF04088.8 CDI86563.1 - 5 7.0 7.2 5.4 6.9 5.0 1.1 1 0 0 1 1 1 0 Peroxin 13, N-terminal region Band_3_cyto PF07565.8 CDI86563.1 - 5 6.5 11.9 5.5 6.4 8.3 1.0 1 0 0 1 1 1 0 Band 3 cytoplasmic domain DUF912 PF06024.7 CDI86563.1 - 5.1 7.2 7.5 6.1 6.9 5.2 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Glyco_transf_15 PF01793.11 CDI86563.1 - 6.5 5.5 10.3 6.6 5.5 7.1 1.1 1 0 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase Suf PF05843.9 CDI86563.1 - 6.8 6.3 15.3 6.7 6.3 10.6 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Med15 PF09606.5 CDI86563.1 - 6.9 4.7 37.0 6.8 4.7 25.7 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal UPF0565 PF10561.4 CDI86563.1 - 7.1 5.4 8.9 7.2 5.4 6.1 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0565 DUF3533 PF12051.3 CDI86563.1 - 7.1 5.2 9.1 6.4 5.4 6.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3533) Peptidase_U57 PF05582.7 CDI86563.1 - 7.2 5.4 10.6 7.4 5.4 7.4 1.0 1 0 0 1 1 1 0 YabG peptidase U57 DUF4557 PF15101.1 CDI86563.1 - 7.2 6.3 20.5 7.2 6.3 14.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) FAM150 PF15129.1 CDI86563.1 - 7.3 6.4 9.1 8.3 6.3 6.3 1.1 1 0 0 1 1 1 0 FAM150 family DUF3381 PF11861.3 CDI86563.1 - 8.2 5.9 16.6 9.2 5.7 11.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) DDHD PF02862.12 CDI86563.1 - 8.2 6.1 11.1 8.4 6.1 7.7 1.0 1 0 0 1 1 1 0 DDHD domain Paf1 PF03985.8 CDI86563.1 - 8.3 5.0 16.2 7.8 5.1 11.3 1.0 1 0 0 1 1 1 0 Paf1 Gti1_Pac2 PF09729.4 CDI86563.1 - 8.5 6.2 7.7 9 6.1 5.3 1.1 1 0 0 1 1 1 0 Gti1/Pac2 family DUF4175 PF13779.1 CDI86563.1 - 9 3.8 35.6 9.5 3.7 24.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Gag_spuma PF03276.9 CDI86563.1 - 9.5 4.4 21.2 9.8 4.3 14.7 1.0 1 0 0 1 1 1 0 Spumavirus gag protein CRF1 PF10380.4 CDI86563.1 - 9.6 6.5 8.6 11 6.4 6.0 1.1 1 0 0 1 1 1 0 Transcription factor CRF1 eIF-3_zeta PF05091.7 CDI86563.1 - 9.9 4.6 14.9 10 4.5 10.3 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) AAA_23 PF13476.1 CDI86564.1 - 0.25 11.6 7.5 0.41 10.9 5.2 1.4 1 0 0 1 1 1 0 AAA domain Bac_Ubq_Cox PF01654.12 CDI86564.1 - 1.1 7.5 12.3 1.4 7.2 8.5 1.1 1 0 0 1 1 1 0 Bacterial Cytochrome Ubiquinol Oxidase IPP-2 PF04979.9 CDI86565.1 - 2.7e-07 30.8 7.0 3e-07 30.7 4.9 1.1 1 0 0 1 1 1 1 Protein phosphatase inhibitor 2 (IPP-2) PcfJ PF14284.1 CDI86565.1 - 0.062 12.7 5.6 0.062 12.8 3.9 1.0 1 0 0 1 1 1 0 PcfJ-like protein DUF1512 PF07431.7 CDI86565.1 - 0.12 11.1 0.0 0.13 11.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1512) SDH_beta PF03315.10 CDI86565.1 - 0.23 11.5 1.5 0.23 11.5 1.0 1.0 1 0 0 1 1 1 0 Serine dehydratase beta chain DUF2353 PF09789.4 CDI86565.1 - 0.34 10.1 11.6 0.41 9.8 8.0 1.0 1 0 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) APG6 PF04111.7 CDI86565.1 - 0.4 9.6 13.7 0.42 9.5 9.5 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 TSC22 PF01166.13 CDI86565.1 - 0.5 10.3 8.4 0.9 9.5 5.8 1.4 1 0 0 1 1 1 0 TSC-22/dip/bun family DUF4337 PF14235.1 CDI86565.1 - 0.59 9.9 7.1 0.66 9.7 4.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) DUF3810 PF12725.2 CDI86565.1 - 0.67 8.7 4.9 0.74 8.6 3.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) Lipoprotein_8 PF02030.10 CDI86565.1 - 0.87 8.0 5.2 0.89 7.9 3.6 1.0 1 0 0 1 1 1 0 Hypothetical lipoprotein (MG045 family) KfrA_N PF11740.3 CDI86565.1 - 1 9.8 12.9 1.2 9.6 8.9 1.1 1 0 0 1 1 1 0 Plasmid replication region DNA-binding N-term DUF342 PF03961.8 CDI86565.1 - 1.8 6.9 9.1 1.8 6.8 6.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF1525 PF07511.6 CDI86565.1 - 3.2 7.7 10.5 3.6 7.6 7.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1525) DUF4407 PF14362.1 CDI86565.1 - 4.5 6.1 7.6 4.8 6.0 5.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) FUSC PF04632.7 CDI86565.1 - 4.9 5.4 5.9 4.9 5.4 4.1 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family VIT1 PF01988.14 CDI86566.1 - 0.32 10.4 0.0 0.32 10.4 0.0 4.1 3 1 1 4 4 4 0 VIT family DUF45 PF01863.12 CDI86566.1 - 2.8 7.6 18.0 0.46 10.2 9.6 1.9 2 0 0 2 2 2 0 Protein of unknown function DUF45 HC2 PF07382.6 CDI86567.1 - 0.13 12.1 30.1 0.15 11.8 20.9 1.1 1 0 0 1 1 1 0 Histone H1-like nucleoprotein HC2 DUF1510 PF07423.6 CDI86567.1 - 1.4 8.2 38.3 1.6 8.0 26.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DUF1777 PF08648.7 CDI86567.1 - 7.1 6.3 40.9 9.1 5.9 28.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) MIP-T3 PF10243.4 CDI86568.1 - 0.0096 14.4 26.9 0.011 14.1 18.6 1.0 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 Shadoo PF14999.1 CDI86568.1 - 0.052 13.3 4.7 0.12 12.2 3.3 1.6 1 0 0 1 1 1 0 Shadow of prion protein, neuroprotective MACPF PF01823.14 CDI86569.1 - 3.8 7.1 9.4 5.9 6.5 6.5 1.2 1 0 0 1 1 1 0 MAC/Perforin domain SRCR_2 PF15494.1 CDI86569.1 - 4.7 7.5 12.5 14 6.0 7.9 2.1 2 0 0 2 2 2 0 Scavenger receptor cysteine-rich domain Suf PF05843.9 CDI86569.1 - 6.8 6.3 8.6 12 5.4 6.0 1.4 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Pex14_N PF04695.8 CDI86570.1 - 0.0016 18.4 24.6 0.0024 17.9 17.0 1.3 1 0 0 1 1 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region VIT1 PF01988.14 CDI86570.1 - 0.013 15.0 4.9 0.016 14.7 3.4 1.1 1 0 0 1 1 1 0 VIT family HGTP_anticodon2 PF12745.2 CDI86570.1 - 0.3 10.1 20.1 0.34 10.0 13.9 1.1 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs Spore_coat_CotO PF14153.1 CDI86570.1 - 0.66 9.3 26.0 0.71 9.2 18.0 1.2 1 0 0 1 1 1 0 Spore coat protein CotO Mem_trans PF03547.13 CDI86570.1 - 0.74 8.0 10.8 0.77 7.9 7.5 1.1 1 0 0 1 1 1 0 Membrane transport protein Draxin PF15550.1 CDI86570.1 - 0.82 9.2 16.1 1.1 8.8 11.2 1.2 1 0 0 1 1 1 0 Draxin Hid1 PF12722.2 CDI86570.1 - 0.89 7.1 18.8 0.83 7.2 13.1 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Corona_nucleoca PF00937.13 CDI86570.1 - 0.91 8.4 20.9 1 8.2 14.5 1.0 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein Plasmodium_Vir PF05795.6 CDI86570.1 - 0.96 8.5 6.6 1.1 8.4 4.6 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Strabismus PF06638.6 CDI86570.1 - 1.2 7.3 10.9 1.3 7.3 7.6 1.1 1 0 0 1 1 1 0 Strabismus protein TT_ORF1 PF02956.9 CDI86570.1 - 1.2 7.5 14.4 1.2 7.4 9.9 1.1 1 0 0 1 1 1 0 TT viral orf 1 ABC2_membrane_2 PF12679.2 CDI86570.1 - 1.4 7.6 6.3 1.8 7.3 4.4 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein Utp14 PF04615.8 CDI86570.1 - 1.6 6.7 25.0 1.6 6.7 17.3 1.0 1 0 0 1 1 1 0 Utp14 protein DUF3984 PF13136.1 CDI86570.1 - 2.1 7.4 14.4 2.4 7.3 10.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3984) Band_3_cyto PF07565.8 CDI86570.1 - 2.4 7.5 19.0 2.9 7.3 13.2 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain SAGA-Tad1 PF12767.2 CDI86570.1 - 2.5 7.7 21.2 2.6 7.6 14.7 1.2 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit Calici_coat_C PF08435.6 CDI86570.1 - 2.6 7.2 17.2 3 7.0 11.9 1.0 1 0 0 1 1 1 0 Calicivirus coat protein C-terminal DUF4045 PF13254.1 CDI86570.1 - 3 7.0 21.3 3.1 6.9 14.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) FLO_LFY PF01698.11 CDI86570.1 - 3.5 6.3 18.0 3.7 6.2 12.5 1.2 1 0 0 1 1 1 0 Floricaula / Leafy protein YjgP_YjgQ PF03739.9 CDI86570.1 - 3.9 6.1 8.5 4.1 6.0 5.9 1.1 1 0 0 1 1 1 0 Predicted permease YjgP/YjgQ family FAM176 PF14851.1 CDI86570.1 - 4.6 6.8 11.0 6.2 6.4 7.6 1.4 1 0 0 1 1 1 0 FAM176 family Tim54 PF11711.3 CDI86570.1 - 4.6 5.7 13.6 4.6 5.7 9.5 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 CDC45 PF02724.9 CDI86570.1 - 4.9 5.0 18.5 4.9 5.0 12.8 1.0 1 0 0 1 1 1 0 CDC45-like protein Cellulose_synt PF03552.9 CDI86570.1 - 4.9 5.3 8.7 4.6 5.4 6.0 1.0 1 0 0 1 1 1 0 Cellulose synthase Dynamin_N PF00350.18 CDI86570.1 - 5.4 6.7 9.5 6 6.6 6.6 1.3 1 0 0 1 1 1 0 Dynamin family Gti1_Pac2 PF09729.4 CDI86570.1 - 6 6.7 15.7 7 6.4 10.9 1.2 1 0 0 1 1 1 0 Gti1/Pac2 family Folate_carrier PF01770.13 CDI86570.1 - 6.3 5.1 12.3 6.8 5.0 8.5 1.2 1 0 0 1 1 1 0 Reduced folate carrier SAPS PF04499.10 CDI86570.1 - 6.8 5.2 16.6 6.4 5.2 11.5 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein G-7-MTase PF12803.2 CDI86570.1 - 6.8 5.7 13.1 7.7 5.5 9.1 1.0 1 0 0 1 1 1 0 mRNA (guanine-7-)methyltransferase (G-7-MTase) CPSF100_C PF13299.1 CDI86570.1 - 7.1 6.7 16.9 8.3 6.5 11.7 1.3 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal SPX PF03105.14 CDI86570.1 - 7.3 6.2 17.8 7.2 6.2 12.3 1.1 1 0 0 1 1 1 0 SPX domain DUF2217 PF10265.4 CDI86570.1 - 7.4 5.2 15.1 7.7 5.1 10.5 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) AUX_IAA PF02309.11 CDI86570.1 - 7.6 6.2 19.9 8.1 6.1 13.8 1.1 1 0 0 1 1 1 0 AUX/IAA family FAM60A PF15396.1 CDI86570.1 - 8.5 6.0 16.9 9.6 5.8 11.7 1.2 1 0 0 1 1 1 0 Protein Family FAM60A eIF-3_zeta PF05091.7 CDI86570.1 - 8.8 4.8 31.5 9.5 4.7 21.8 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) NPR3 PF03666.8 CDI86570.1 - 8.9 4.7 19.5 9 4.6 13.5 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Glyco_transf_15 PF01793.11 CDI86570.1 - 9 5.1 20.2 9.6 5.0 14.0 1.1 1 0 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase DUF966 PF06136.8 CDI86570.1 - 9 5.5 20.6 9.1 5.5 14.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF966) FemAB PF02388.11 CDI86570.1 - 9.6 4.7 20.2 9.1 4.8 14.0 1.1 1 0 0 1 1 1 0 FemAB family DUF72 PF01904.13 CDI86572.1 - 0.036 13.7 0.0 0.075 12.7 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function DUF72 Utp12 PF04003.7 CDI86573.1 - 0.074 12.9 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 Dip2/Utp12 Family DUF3093 PF11292.3 CDI86573.1 - 0.17 11.6 0.0 0.3 10.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3093) Utp14 PF04615.8 CDI86574.1 - 9 4.3 20.1 11 3.9 13.9 1.0 1 0 0 1 1 1 0 Utp14 protein Ribosomal_60s PF00428.14 CDI86575.1 - 0.0099 16.2 7.2 0.0099 16.2 5.0 3.3 2 1 1 3 3 3 1 60s Acidic ribosomal protein ELL PF10390.4 CDI86575.1 - 6.4 5.9 11.2 8.6 5.4 7.8 1.1 1 0 0 1 1 1 0 RNA polymerase II elongation factor ELL CytochromB561_N PF09786.4 CDI86575.1 - 7.3 4.9 19.2 8.8 4.6 13.3 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal PAT1 PF09770.4 CDI86576.1 - 1.4 7.0 49.9 1.6 6.8 34.6 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 CRT10 PF08728.5 CDI86576.1 - 10 3.9 10.1 11 3.8 7.0 1.0 1 0 0 1 1 1 0 CRT10 SR-25 PF10500.4 CDI86578.1 - 5.1e-07 29.4 13.5 5.1e-07 29.4 9.4 11.9 5 3 4 9 9 9 1 Nuclear RNA-splicing-associated protein PAT1 PF09770.4 CDI86580.1 - 0.024 12.9 89.3 0.029 12.6 61.9 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF445 PF04286.7 CDI86580.1 - 1.2 8.5 29.7 1.8 7.9 20.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF445) Chorion_2 PF03964.10 CDI86580.1 - 3.4 8.2 15.9 0.8 10.2 2.4 2.5 2 0 0 2 2 2 0 Chorion family 2 SpoIIIAH PF12685.2 CDI86581.1 - 0.0021 17.5 11.2 0.0021 17.5 7.8 2.3 2 0 0 2 2 2 1 SpoIIIAH-like protein PRA1 PF03208.14 CDI86581.1 - 0.063 12.6 0.4 0.14 11.4 0.3 1.6 1 0 0 1 1 1 0 PRA1 family protein FlaC_arch PF05377.6 CDI86581.1 - 0.54 10.1 5.2 0.73 9.7 0.2 2.8 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) DUF843 PF05814.6 CDI86581.1 - 3 7.6 6.6 43 4.0 4.6 2.8 1 1 0 1 1 1 0 Baculovirus protein of unknown function (DUF843) AAA_4 PF04326.9 CDI86581.1 - 5.3 7.2 11.6 27 4.9 0.0 3.0 1 1 1 2 2 2 0 Divergent AAA domain Herpes_UL87 PF03043.9 CDI86581.1 - 7.5 4.8 26.0 9.5 4.4 18.0 1.0 1 0 0 1 1 1 0 Herpesvirus UL87 family UPF0118 PF01594.11 CDI86581.1 - 7.8 5.3 15.3 0.21 10.5 2.1 2.3 1 1 0 2 2 2 0 Domain of unknown function DUF20 TFIIA PF03153.8 CDI86581.1 - 9.4 6.0 50.0 14 5.4 34.7 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit TPR_14 PF13428.1 CDI86582.1 - 0.0027 18.1 14.2 0.0081 16.7 2.7 4.1 2 1 2 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.1 CDI86582.1 - 0.0094 15.8 4.5 0.0094 15.8 3.1 2.5 3 1 0 3 3 2 1 Tetratricopeptide repeat Apc3 PF12895.2 CDI86582.1 - 0.015 15.4 3.2 0.022 14.8 0.5 2.4 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.1 CDI86582.1 - 0.022 14.4 1.5 0.68 9.8 0.4 3.2 2 1 0 2 2 2 0 Tetratricopeptide repeat Coatomer_WDAD PF04053.9 CDI86582.1 - 0.025 13.3 1.8 0.028 13.2 1.2 1.1 1 0 0 1 1 1 0 Coatomer WD associated region TPR_7 PF13176.1 CDI86582.1 - 0.032 14.0 6.7 0.6 10.0 1.7 3.7 3 1 0 3 3 3 0 Tetratricopeptide repeat DUF3366 PF11846.3 CDI86582.1 - 0.032 14.1 2.2 0.042 13.7 1.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3366) TPR_1 PF00515.23 CDI86582.1 - 0.035 13.7 5.1 0.21 11.2 1.2 3.5 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.12 CDI86582.1 - 0.036 13.9 2.1 0.036 13.9 1.5 3.6 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_4 PF07721.9 CDI86582.1 - 0.094 13.1 0.1 0.094 13.1 0.1 5.1 3 1 3 6 6 6 0 Tetratricopeptide repeat SNAP PF14938.1 CDI86582.1 - 0.098 11.7 8.2 0.21 10.6 5.7 1.5 1 1 0 1 1 1 0 Soluble NSF attachment protein, SNAP TPR_19 PF14559.1 CDI86582.1 - 0.62 10.4 8.6 5.2 7.4 5.5 2.8 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.1 CDI86582.1 - 0.97 9.1 7.7 0.22 11.1 1.6 2.6 2 1 1 3 3 2 0 TPR repeat TPR_10 PF13374.1 CDI86582.1 - 2.4 8.2 14.1 2.8 8.0 0.8 4.0 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.1 CDI86582.1 - 8.8 7.1 18.7 0.27 11.9 4.6 3.2 2 1 2 4 4 4 0 Tetratricopeptide repeat DUF1510 PF07423.6 CDI86583.1 - 8.3e-08 31.8 5.8 9.2e-08 31.7 4.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) TRAP_alpha PF03896.11 CDI86583.1 - 1.4e-05 24.2 3.8 1.7e-05 23.9 2.6 1.2 1 0 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit SpoIIIAH PF12685.2 CDI86583.1 - 2.3e-05 23.9 3.5 2.9e-05 23.6 2.4 1.1 1 0 0 1 1 1 1 SpoIIIAH-like protein IncA PF04156.9 CDI86583.1 - 0.00024 20.7 28.4 0.00028 20.5 19.7 1.0 1 0 0 1 1 1 1 IncA protein Ycf1 PF05758.7 CDI86583.1 - 0.00032 18.6 7.7 0.00034 18.4 5.4 1.0 1 0 0 1 1 1 1 Ycf1 RIC3 PF15361.1 CDI86583.1 - 0.00052 20.2 2.2 0.00066 19.9 1.5 1.1 1 0 0 1 1 1 1 Resistance to inhibitors of cholinesterase homologue 3 SID-1_RNA_chan PF13965.1 CDI86583.1 - 0.00065 17.9 1.5 0.00077 17.7 1.1 1.1 1 0 0 1 1 1 1 dsRNA-gated channel SID-1 Neur_chan_memb PF02932.11 CDI86583.1 - 0.00077 19.4 0.6 0.00085 19.2 0.4 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region DUF4446 PF14584.1 CDI86583.1 - 0.0016 18.2 7.0 0.0022 17.8 4.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4446) Peptidase_S49_N PF08496.5 CDI86583.1 - 0.0016 18.2 5.2 0.0018 18.0 3.6 1.1 1 0 0 1 1 1 1 Peptidase family S49 N-terminal DUF4131 PF13567.1 CDI86583.1 - 0.0018 17.7 2.3 0.0021 17.4 1.6 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4131) DUF3260 PF11658.3 CDI86583.1 - 0.0027 15.9 4.6 0.0029 15.8 3.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3260) Serinc PF03348.10 CDI86583.1 - 0.0042 15.8 4.6 0.0049 15.6 3.2 1.2 1 0 0 1 1 1 1 Serine incorporator (Serinc) Adipogenin PF15202.1 CDI86583.1 - 0.0045 16.8 0.5 0.0077 16.0 0.3 1.4 1 0 0 1 1 1 1 Adipogenin DUF3328 PF11807.3 CDI86583.1 - 0.0048 16.6 0.7 0.0082 15.8 0.5 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) Shisa PF13908.1 CDI86583.1 - 0.0057 16.8 0.3 0.0064 16.6 0.2 1.2 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator DUF1980 PF09323.5 CDI86583.1 - 0.0065 16.2 2.2 0.0081 15.9 1.5 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1980) Herpes_gE PF02480.11 CDI86583.1 - 0.01 14.1 0.0 0.011 14.0 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Folate_carrier PF01770.13 CDI86583.1 - 0.013 14.0 2.0 0.015 13.7 1.4 1.2 1 0 0 1 1 1 0 Reduced folate carrier Tetraspannin PF00335.15 CDI86583.1 - 0.015 14.6 0.6 0.016 14.4 0.4 1.1 1 0 0 1 1 1 0 Tetraspanin family DUF4512 PF14975.1 CDI86583.1 - 0.028 15.2 1.5 0.04 14.7 1.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4512) DUF2254 PF10011.4 CDI86583.1 - 0.035 12.5 0.4 0.041 12.3 0.3 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2254) Calc_CGRP_IAPP PF00214.14 CDI86583.1 - 0.049 13.6 6.6 0.069 13.1 4.6 1.3 1 0 0 1 1 1 0 Calcitonin / CGRP / IAPP family Pex24p PF06398.6 CDI86583.1 - 0.058 12.1 0.8 0.082 11.6 0.5 1.3 1 1 0 1 1 1 0 Integral peroxisomal membrane peroxin Endonuc_Holl PF10107.4 CDI86583.1 - 0.068 12.8 11.4 0.096 12.3 7.9 1.3 1 0 0 1 1 1 0 Endonuclease related to archaeal Holliday junction resolvase DUF3752 PF12572.3 CDI86583.1 - 0.07 13.2 14.9 0.1 12.7 10.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3752) OATP PF03137.15 CDI86583.1 - 0.097 10.7 2.4 0.12 10.3 1.7 1.3 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family ATP-synt_8 PF00895.15 CDI86583.1 - 0.12 12.5 0.3 0.28 11.4 0.2 1.6 1 0 0 1 1 1 0 ATP synthase protein 8 DUF2232 PF09991.4 CDI86583.1 - 0.13 11.1 5.0 0.16 10.9 3.5 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) Herpes_glycop PF01528.11 CDI86583.1 - 0.14 10.8 0.1 0.18 10.4 0.1 1.1 1 0 0 1 1 1 0 Herpesvirus glycoprotein M SAPS PF04499.10 CDI86583.1 - 0.22 10.1 11.2 0.25 9.9 7.8 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein SeqA PF03925.8 CDI86583.1 - 0.23 11.1 11.2 0.31 10.7 7.7 1.2 1 0 0 1 1 1 0 SeqA protein YqfQ PF14181.1 CDI86583.1 - 0.37 10.8 16.0 0.43 10.6 11.1 1.1 1 0 0 1 1 1 0 YqfQ-like protein TT_ORF1 PF02956.9 CDI86583.1 - 0.4 9.0 7.1 0.43 8.9 4.9 1.0 1 0 0 1 1 1 0 TT viral orf 1 F-protein PF00469.15 CDI86583.1 - 0.42 9.9 13.9 0.5 9.6 9.6 1.0 1 0 0 1 1 1 0 Negative factor, (F-Protein) or Nef PAT1 PF09770.4 CDI86583.1 - 0.45 8.7 27.8 0.52 8.4 19.3 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF3450 PF11932.3 CDI86583.1 - 0.45 9.7 23.7 0.53 9.5 16.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF3381 PF11861.3 CDI86583.1 - 0.47 9.9 20.5 0.57 9.6 14.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) DUF3366 PF11846.3 CDI86583.1 - 0.49 10.2 5.6 0.78 9.5 3.9 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF3366) DUF2370 PF10176.4 CDI86583.1 - 0.59 9.4 4.9 0.7 9.1 3.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) DUF3449 PF11931.3 CDI86583.1 - 0.61 9.5 15.9 0.73 9.3 11.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3449) Selenoprotein_S PF06936.6 CDI86583.1 - 0.64 9.5 12.0 0.77 9.2 8.3 1.1 1 0 0 1 1 1 0 Selenoprotein S (SelS) Herpes_env PF01673.13 CDI86583.1 - 0.68 8.4 7.4 0.79 8.2 5.1 1.0 1 0 0 1 1 1 0 Herpesvirus putative major envelope glycoprotein DUF1764 PF08576.5 CDI86583.1 - 0.69 10.7 14.5 0.97 10.2 10.1 1.2 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) DUF501 PF04417.7 CDI86583.1 - 0.74 9.6 5.3 0.95 9.3 3.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF501) Band_3_cyto PF07565.8 CDI86583.1 - 0.78 9.2 12.9 0.94 8.9 9.0 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain DUF2052 PF09747.4 CDI86583.1 - 0.88 9.4 23.3 1.1 9.1 16.2 1.1 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) RR_TM4-6 PF06459.7 CDI86583.1 - 1.3 8.8 20.0 1.5 8.6 13.9 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SpoIIP PF07454.6 CDI86583.1 - 1.3 8.1 12.9 1.5 7.8 8.9 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Spore_coat_CotO PF14153.1 CDI86583.1 - 1.4 8.3 29.1 1.6 8.1 20.1 1.1 1 0 0 1 1 1 0 Spore coat protein CotO DUF913 PF06025.7 CDI86583.1 - 1.4 7.5 5.9 1.6 7.4 4.1 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) FimP PF09766.4 CDI86583.1 - 1.4 7.8 24.2 1.9 7.4 16.8 1.2 1 0 0 1 1 1 0 Fms-interacting protein FLO_LFY PF01698.11 CDI86583.1 - 1.6 7.5 15.7 1.9 7.2 10.9 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein DUF4045 PF13254.1 CDI86583.1 - 1.6 7.9 14.5 1.8 7.7 10.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Gag_spuma PF03276.9 CDI86583.1 - 1.7 6.9 20.7 1.9 6.7 14.3 1.0 1 0 0 1 1 1 0 Spumavirus gag protein Tim54 PF11711.3 CDI86583.1 - 1.7 7.1 13.1 1.9 6.9 9.1 1.0 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Pox_Ag35 PF03286.9 CDI86583.1 - 1.7 8.1 11.5 2.2 7.7 8.0 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein MSA-2c PF12238.3 CDI86583.1 - 1.7 8.2 9.3 2.2 7.9 6.4 1.1 1 0 0 1 1 1 0 Merozoite surface antigen 2c Vfa1 PF08432.5 CDI86583.1 - 1.8 8.5 17.3 2.3 8.2 12.0 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 7tm_1 PF00001.16 CDI86583.1 - 1.9 7.5 5.3 3.7 6.6 3.7 1.5 1 1 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) FYDLN_acid PF09538.5 CDI86583.1 - 1.9 9.0 13.6 3 8.4 9.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) Cellulose_synt PF03552.9 CDI86583.1 - 2 6.6 6.8 2.3 6.3 4.7 1.1 1 0 0 1 1 1 0 Cellulose synthase BTV_NS2 PF04514.7 CDI86583.1 - 2.1 7.1 16.1 2.4 6.9 11.2 1.0 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Gemini_mov PF01708.11 CDI86583.1 - 2.3 7.7 10.0 0.27 10.8 3.3 1.9 1 1 1 2 2 2 0 Geminivirus putative movement protein Hid1 PF12722.2 CDI86583.1 - 2.4 5.7 13.5 2.7 5.5 9.4 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein ARGLU PF15346.1 CDI86583.1 - 2.7 7.7 32.2 3.4 7.4 22.3 1.1 1 0 0 1 1 1 0 Arginine and glutamate-rich 1 GDE_N PF12439.3 CDI86583.1 - 3.1 6.9 9.8 3.8 6.6 6.8 1.0 1 0 0 1 1 1 0 Glycogen debranching enzyme N terminal GAGA_bind PF06217.7 CDI86583.1 - 3.4 7.5 12.2 4 7.3 8.5 1.0 1 0 0 1 1 1 0 GAGA binding protein-like family DUF972 PF06156.8 CDI86583.1 - 3.4 8.0 16.3 4.3 7.7 11.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF972) CKAP2_C PF15297.1 CDI86583.1 - 3.4 6.3 19.0 4.2 6.0 13.2 1.0 1 0 0 1 1 1 0 Cytoskeleton-associated protein 2 C-terminus Nucleoside_tran PF01733.13 CDI86583.1 - 3.5 6.7 9.5 10 5.1 6.6 1.7 1 1 0 1 1 1 0 Nucleoside transporter Hom_end_hint PF05203.11 CDI86583.1 - 4 7.1 10.1 4.8 6.8 7.0 1.1 1 0 0 1 1 1 0 Hom_end-associated Hint DUF2407_C PF13373.1 CDI86583.1 - 4.5 7.1 11.6 5.9 6.8 8.1 1.2 1 0 0 1 1 1 0 DUF2407 C-terminal domain DDRGK PF09756.4 CDI86583.1 - 5 6.4 28.4 6.1 6.2 19.7 1.1 1 0 0 1 1 1 0 DDRGK domain DUF2126 PF09899.4 CDI86583.1 - 5 5.0 11.1 5.6 4.8 7.7 1.0 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) YABBY PF04690.8 CDI86583.1 - 5.2 7.2 7.4 6.1 7.0 5.1 1.1 1 0 0 1 1 1 0 YABBY protein Ctr PF04145.10 CDI86583.1 - 6 6.9 12.6 48 3.9 8.7 1.9 1 1 0 1 1 1 0 Ctr copper transporter family Gti1_Pac2 PF09729.4 CDI86583.1 - 6.4 6.6 8.5 8.8 6.1 5.9 1.3 1 0 0 1 1 1 0 Gti1/Pac2 family VID27 PF08553.5 CDI86583.1 - 6.5 4.8 14.9 7.7 4.6 10.3 1.0 1 0 0 1 1 1 0 VID27 cytoplasmic protein DUF2347 PF09804.4 CDI86583.1 - 6.8 5.8 11.1 8.1 5.6 7.7 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2347) Suf PF05843.9 CDI86583.1 - 7.8 6.1 17.6 9.4 5.8 12.2 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) CDC45 PF02724.9 CDI86583.1 - 8.7 4.2 18.6 10 3.9 12.9 1.0 1 0 0 1 1 1 0 CDC45-like protein Herpes_DNAp_acc PF04929.7 CDI86583.1 - 9.3 5.0 11.6 11 4.9 8.1 1.0 1 0 0 1 1 1 0 Herpes DNA replication accessory factor FAM60A PF15396.1 CDI86583.1 - 9.7 5.8 9.8 11 5.6 6.8 1.1 1 0 0 1 1 1 0 Protein Family FAM60A DDHD PF02862.12 CDI86583.1 - 9.8 5.8 16.5 12 5.5 11.4 1.1 1 0 0 1 1 1 0 DDHD domain Ras PF00071.17 CDI86584.1 - 3.2e-37 127.3 0.9 4.5e-27 94.4 0.1 2.0 1 1 1 2 2 2 2 Ras family Miro PF08477.8 CDI86584.1 - 1.4e-06 28.7 0.0 5.4e-06 26.8 0.0 1.8 1 1 0 1 1 1 1 Miro-like protein Arf PF00025.16 CDI86584.1 - 0.00056 19.1 0.2 0.0019 17.4 0.0 1.7 1 1 1 2 2 2 1 ADP-ribosylation factor family FIIND PF13553.1 CDI86584.1 - 0.019 14.3 0.1 0.55 9.6 0.0 2.0 1 1 1 2 2 2 0 Function to find Augurin PF15187.1 CDI86584.1 - 0.024 14.5 0.0 2.4 8.0 0.0 2.1 1 1 1 2 2 2 0 Oesophageal cancer-related gene 4 GTP_EFTU PF00009.22 CDI86584.1 - 0.12 11.8 0.0 0.13 11.6 0.0 1.1 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain Peptidase_C48 PF02902.14 CDI86586.1 - 3.3e-07 30.1 0.0 7.5e-07 28.9 0.0 1.5 2 0 0 2 2 2 1 Ulp1 protease family, C-terminal catalytic domain BRF1 PF07741.8 CDI86587.1 - 0.0031 17.7 0.5 0.0031 17.7 0.4 2.2 2 0 0 2 2 1 1 Brf1-like TBP-binding domain PAP_RNA-bind PF04926.10 CDI86587.1 - 0.0089 15.5 0.3 0.0089 15.5 0.2 2.1 2 0 0 2 2 2 1 Poly(A) polymerase predicted RNA binding domain RIC3 PF15361.1 CDI86587.1 - 0.011 15.9 19.9 0.43 10.8 0.7 2.2 2 0 0 2 2 2 0 Resistance to inhibitors of cholinesterase homologue 3 DUF4175 PF13779.1 CDI86587.1 - 0.027 12.2 44.5 0.035 11.8 14.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4175) EmrE PF13536.1 CDI86587.1 - 0.027 14.6 0.8 0.046 13.9 0.5 1.3 1 0 0 1 1 1 0 Multidrug resistance efflux transporter PIG-U PF06728.8 CDI86587.1 - 0.031 13.1 0.0 0.037 12.9 0.0 1.1 1 0 0 1 1 1 0 GPI transamidase subunit PIG-U Trypan_glycop_C PF10659.4 CDI86587.1 - 0.036 14.3 0.5 0.036 14.3 0.3 2.2 2 0 0 2 2 2 0 Trypanosome variant surface glycoprotein C-terminal domain DUF4557 PF15101.1 CDI86587.1 - 0.04 13.7 25.7 0.14 11.9 3.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4557) AzlC PF03591.9 CDI86587.1 - 0.05 13.5 2.0 0.096 12.6 1.4 1.5 1 0 0 1 1 1 0 AzlC protein Peptidase_S49_N PF08496.5 CDI86587.1 - 0.12 12.1 10.4 0.74 9.6 0.8 2.2 2 0 0 2 2 2 0 Peptidase family S49 N-terminal PH_4 PF15404.1 CDI86587.1 - 0.14 11.6 9.0 0.59 9.6 0.1 2.2 2 0 0 2 2 2 0 Pleckstrin homology domain IncA PF04156.9 CDI86587.1 - 0.18 11.3 24.5 0.13 11.8 6.0 2.3 2 0 0 2 2 2 0 IncA protein Neur_chan_memb PF02932.11 CDI86587.1 - 0.19 11.6 8.4 0.27 11.0 5.8 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region HD-ZIP_N PF04618.7 CDI86587.1 - 0.19 12.2 12.6 0.76 10.3 0.3 2.2 2 0 0 2 2 2 0 HD-ZIP protein N terminus EPL1 PF10513.4 CDI86587.1 - 0.24 11.6 19.5 0.86 9.8 0.6 2.1 2 0 0 2 2 2 0 Enhancer of polycomb-like Folate_carrier PF01770.13 CDI86587.1 - 0.28 9.6 6.5 2.6 6.4 1.1 2.1 2 0 0 2 2 2 0 Reduced folate carrier Peroxin-13_N PF04088.8 CDI86587.1 - 0.42 10.5 6.0 4.3 7.2 0.1 2.1 2 0 0 2 2 2 0 Peroxin 13, N-terminal region Spore_YhcN_YlaJ PF09580.5 CDI86587.1 - 0.49 10.4 13.5 2.4 8.2 3.4 2.0 2 0 0 2 2 2 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) G0-G1_switch_2 PF15103.1 CDI86587.1 - 0.54 10.5 14.4 0.2 11.9 0.3 2.3 2 0 0 2 2 2 0 G0/G1 switch protein 2 DUF912 PF06024.7 CDI86587.1 - 0.7 9.9 12.5 0.39 10.7 0.2 2.3 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) PBP1_TM PF14812.1 CDI86587.1 - 0.78 10.0 6.6 5.4 7.3 0.0 2.2 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Herpes_DNAp_acc PF04929.7 CDI86587.1 - 0.98 8.3 16.4 0.88 8.4 4.1 2.1 2 0 0 2 2 2 0 Herpes DNA replication accessory factor CPSF100_C PF13299.1 CDI86587.1 - 1 9.4 11.2 3.5 7.7 0.2 2.1 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal WBS_methylT PF12589.3 CDI86587.1 - 1.4 9.4 18.8 0.28 11.6 0.8 2.1 2 0 0 2 2 2 0 Methyltransferase involved in Williams-Beuren syndrome Band_3_cyto PF07565.8 CDI86587.1 - 1.8 8.0 20.9 0.62 9.5 0.3 2.1 2 0 0 2 2 2 0 Band 3 cytoplasmic domain FimP PF09766.4 CDI86587.1 - 1.8 7.5 37.1 1.5 7.8 8.5 2.1 2 0 0 2 2 2 0 Fms-interacting protein SHR3_chaperone PF08229.6 CDI86587.1 - 2.1 7.2 19.7 2 7.3 4.3 2.5 2 0 0 2 2 2 0 ER membrane protein SH3 PSCyt3 PF07627.6 CDI86587.1 - 2.2 8.2 14.2 0.54 10.1 2.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1588) TCP PF03634.8 CDI86587.1 - 2.5 8.4 21.3 4.1 7.7 6.8 2.1 2 0 0 2 2 2 0 TCP family transcription factor ATAD4 PF15321.1 CDI86587.1 - 3.8 8.5 19.2 3.1 8.8 1.8 2.2 2 0 0 2 2 2 0 ATPase family AAA domain containing 4 Conotoxin PF02950.12 CDI86587.1 - 3.8 8.3 16.9 1.3 9.8 2.5 2.7 2 0 0 2 2 2 0 Conotoxin Baculo_PP31 PF05311.6 CDI86587.1 - 4 6.6 17.5 2.4 7.3 1.9 2.1 2 0 0 2 2 2 0 Baculovirus 33KDa late protein (PP31) PSK PF06404.7 CDI86587.1 - 4 8.2 16.9 2.8 8.7 1.2 2.6 3 0 0 3 3 2 0 Phytosulfokine precursor protein (PSK) Ribosomal_60s PF00428.14 CDI86587.1 - 4.4 7.7 12.1 9.8 6.6 3.4 2.9 3 0 0 3 3 3 0 60s Acidic ribosomal protein BNIP3 PF06553.7 CDI86587.1 - 6.3 6.1 14.1 2.5 7.4 3.6 2.1 2 0 0 2 2 2 0 BNIP3 FNIP_N PF14636.1 CDI86587.1 - 6.6 7.2 20.4 2.1 8.7 5.0 2.1 2 0 0 2 2 2 0 Folliculin-interacting protein N-terminus BORG_CEP PF14957.1 CDI86587.1 - 8.6 7.3 14.5 11 6.9 0.3 2.1 2 0 0 2 2 2 0 Cdc42 effector WWbp PF10349.4 CDI86587.1 - 9.7 7.1 22.6 10 7.0 2.9 2.2 2 0 0 2 2 2 0 WW-domain ligand protein WD40 PF00400.27 CDI86588.1 - 2e-29 100.3 9.7 3.1e-10 39.5 0.1 3.1 3 0 0 3 3 3 3 WD domain, G-beta repeat Apc4_WD40 PF12894.2 CDI86588.1 - 1.2e-05 24.7 0.0 1.3 8.5 0.0 3.2 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Nbas_N PF15492.1 CDI86588.1 - 0.0035 16.4 0.7 0.0035 16.4 0.5 2.0 1 1 1 2 2 2 1 Neuroblastoma-amplified sequence, N terminal FimP PF09766.4 CDI86588.1 - 0.017 14.2 26.3 0.19 10.7 7.1 2.0 2 0 0 2 2 2 0 Fms-interacting protein Trp_oprn_chp PF09534.5 CDI86588.1 - 0.018 14.6 0.4 0.085 12.4 0.3 1.8 1 1 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Rtf2 PF04641.7 CDI86588.1 - 0.021 14.0 8.8 0.03 13.5 6.1 1.2 1 0 0 1 1 1 0 Rtf2 RING-finger TFIIIC_delta PF12657.2 CDI86588.1 - 0.022 14.4 11.3 0.1 12.2 7.5 2.0 1 1 1 2 2 2 0 Transcription factor IIIC subunit delta N-term DUF2407_C PF13373.1 CDI86588.1 - 0.044 13.6 5.0 0.66 9.9 0.1 2.1 2 0 0 2 2 2 0 DUF2407 C-terminal domain FKS1_dom1 PF14288.1 CDI86588.1 - 0.049 13.5 0.5 0.049 13.5 0.4 2.1 2 0 0 2 2 2 0 1,3-beta-glucan synthase subunit FKS1, domain-1 DUF3371 PF11851.3 CDI86588.1 - 0.063 13.9 18.0 0.92 10.1 4.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3371) DUF1800 PF08811.6 CDI86588.1 - 0.08 11.8 12.4 0.093 11.6 8.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1800) CBP4 PF07960.6 CDI86588.1 - 0.088 12.4 22.6 0.032 13.8 3.8 2.1 2 0 0 2 2 2 0 CBP4 DUF533 PF04391.7 CDI86588.1 - 0.11 11.8 20.1 0.063 12.6 2.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF533) Oleosin PF01277.12 CDI86588.1 - 0.13 11.8 8.6 0.99 8.9 0.5 2.2 2 0 0 2 2 2 0 Oleosin SRP14 PF02290.10 CDI86588.1 - 0.14 12.1 2.3 7.8 6.4 0.1 2.3 2 0 0 2 2 2 0 Signal recognition particle 14kD protein EphA2_TM PF14575.1 CDI86588.1 - 0.14 12.5 5.4 3.9 7.9 0.3 2.4 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Neur_chan_memb PF02932.11 CDI86588.1 - 0.14 12.0 7.9 0.18 11.6 5.5 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Zip PF02535.17 CDI86588.1 - 0.14 11.1 0.9 0.2 10.6 0.6 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter PSK PF06404.7 CDI86588.1 - 0.17 12.6 7.0 1.9 9.3 0.4 2.2 2 0 0 2 2 2 0 Phytosulfokine precursor protein (PSK) FCP1_C PF09309.5 CDI86588.1 - 0.3 10.3 20.4 0.94 8.7 4.5 2.1 2 0 0 2 2 2 0 FCP1, C-terminal Peroxin-13_N PF04088.8 CDI86588.1 - 0.4 10.6 6.1 3.6 7.5 0.2 2.1 2 0 0 2 2 2 0 Peroxin 13, N-terminal region DUF2611 PF11022.3 CDI86588.1 - 0.41 10.7 2.7 4.3 7.4 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2611) DUF3752 PF12572.3 CDI86588.1 - 0.42 10.7 14.0 0.71 9.9 2.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3752) DUF702 PF05142.7 CDI86588.1 - 0.46 10.6 14.0 2 8.5 2.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF702) NPCC PF08058.6 CDI86588.1 - 0.55 10.0 5.3 0.11 12.4 0.4 1.8 1 1 1 2 2 2 0 Nuclear pore complex component DUF3408 PF11888.3 CDI86588.1 - 0.57 10.1 11.7 2.3 8.1 1.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3408) HNOBA PF07701.9 CDI86588.1 - 0.66 9.1 9.6 2.8 7.0 0.5 2.1 2 0 0 2 2 2 0 Heme NO binding associated Presenilin PF01080.12 CDI86588.1 - 0.78 8.5 7.2 0.99 8.1 5.0 1.1 1 0 0 1 1 1 0 Presenilin Rsc14 PF08586.5 CDI86588.1 - 0.78 10.2 8.6 3.5 8.1 0.3 2.2 2 0 0 2 2 2 0 RSC complex, Rsc14/Ldb7 subunit FYDLN_acid PF09538.5 CDI86588.1 - 0.9 10.1 6.9 6.3 7.4 0.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) PIRT PF15099.1 CDI86588.1 - 0.9 8.7 6.6 6.2 6.0 0.1 2.3 2 0 0 2 2 2 0 Phosphoinositide-interacting protein family DnaJ-X PF14308.1 CDI86588.1 - 0.9 8.7 13.0 2.4 7.4 1.1 2.1 2 0 0 2 2 2 0 X-domain of DnaJ-containing zf-DHHC PF01529.15 CDI86588.1 - 1.1 8.5 7.6 2.9 7.2 0.5 2.1 2 0 0 2 2 2 0 DHHC palmitoyltransferase CagX PF03524.10 CDI86588.1 - 1.4 8.1 12.0 1.5 8.0 1.2 2.1 2 0 0 2 2 2 0 Conjugal transfer protein PBP1_TM PF14812.1 CDI86588.1 - 1.5 9.1 7.8 3.4 8.0 0.6 2.2 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF4175 PF13779.1 CDI86588.1 - 1.5 6.3 47.2 1.5 6.3 16.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4175) PH_4 PF15404.1 CDI86588.1 - 1.6 8.2 13.2 1.8 8.0 1.5 2.1 2 0 0 2 2 2 0 Pleckstrin homology domain Trypan_glycop_C PF10659.4 CDI86588.1 - 1.6 9.0 13.1 2.6 8.3 1.6 2.2 2 0 0 2 2 2 0 Trypanosome variant surface glycoprotein C-terminal domain Rxt3 PF08642.5 CDI86588.1 - 1.7 8.9 6.5 11 6.3 0.6 2.3 2 0 0 2 2 2 0 Histone deacetylation protein Rxt3 Hep_59 PF07052.6 CDI86588.1 - 1.7 9.0 16.9 0.84 10.0 3.3 2.2 2 0 0 2 2 2 0 Hepatocellular carcinoma-associated antigen 59 BAF1_ABF1 PF04684.8 CDI86588.1 - 1.8 7.2 37.1 2.2 7.0 9.2 2.1 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor TMEM51 PF15345.1 CDI86588.1 - 2.4 7.7 17.4 0.22 11.1 1.2 2.1 2 0 0 2 2 2 0 Transmembrane protein 51 Prog_receptor PF02161.10 CDI86588.1 - 2.4 6.8 11.1 1.9 7.2 2.1 2.0 2 0 0 2 2 2 0 Progesterone receptor Rpp20 PF12328.3 CDI86588.1 - 2.5 7.7 13.1 2.8 7.6 1.4 2.2 2 0 0 2 2 2 0 Rpp20 subunit of nuclear RNase MRP and P PRP3 PF08572.5 CDI86588.1 - 2.5 7.4 20.4 3.5 6.9 4.6 2.1 2 0 0 2 2 2 0 pre-mRNA processing factor 3 (PRP3) DUF2722 PF10846.3 CDI86588.1 - 2.7 6.9 24.5 0.77 8.7 4.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) DUF1676 PF07898.8 CDI86588.1 - 2.7 8.3 5.7 9.1 6.6 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1676) Hid1 PF12722.2 CDI86588.1 - 3.1 5.3 13.6 4 4.9 9.4 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Topoisom_I_N PF02919.10 CDI86588.1 - 3.2 6.9 12.2 0.51 9.5 2.2 2.1 2 0 0 2 2 2 0 Eukaryotic DNA topoisomerase I, DNA binding fragment ATAD4 PF15321.1 CDI86588.1 - 3.3 8.7 15.2 4.7 8.2 2.0 2.2 2 0 0 2 2 2 0 ATPase family AAA domain containing 4 BTV_NS2 PF04514.7 CDI86588.1 - 3.4 6.4 12.9 3 6.6 1.6 2.0 2 0 0 2 2 2 0 Bluetongue virus non-structural protein NS2 Spore_coat_CotO PF14153.1 CDI86588.1 - 3.6 6.9 24.1 1.9 7.8 4.8 2.1 2 0 0 2 2 2 0 Spore coat protein CotO Dehydrin PF00257.14 CDI86588.1 - 4.1 7.7 22.2 6.1 7.1 2.8 2.2 2 0 0 2 2 2 0 Dehydrin RNA_lig_T4_1 PF09511.5 CDI86588.1 - 4.2 6.7 9.1 7.1 6.0 0.7 2.1 1 1 1 2 2 2 0 RNA ligase Fes1 PF08609.5 CDI86588.1 - 4.3 7.8 10.3 2.4 8.6 0.7 2.3 2 0 0 2 2 2 0 Nucleotide exchange factor Fes1 DUF2502 PF10697.4 CDI86588.1 - 4.3 7.5 16.0 2.5 8.2 1.2 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2502) DUF1764 PF08576.5 CDI86588.1 - 5 7.9 18.4 5.6 7.7 2.8 2.2 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF1764) DUF912 PF06024.7 CDI86588.1 - 5.1 7.2 11.4 7.5 6.6 1.5 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Peptidase_S49_N PF08496.5 CDI86588.1 - 5.2 6.8 14.1 2.4 7.9 1.5 2.1 2 0 0 2 2 2 0 Peptidase family S49 N-terminal dsDNA_bind PF01984.15 CDI86588.1 - 5.4 7.0 45.2 0.76 9.8 12.8 2.2 2 0 0 2 2 2 0 Double-stranded DNA-binding domain Pkinase PF00069.20 CDI86588.1 - 6.4 5.8 8.2 0.3 10.1 0.7 1.9 1 1 1 2 2 2 0 Protein kinase domain DUF3306 PF11748.3 CDI86588.1 - 6.5 7.4 17.0 3.6 8.2 2.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3306) DUF3043 PF11241.3 CDI86588.1 - 7 6.2 11.6 4.4 6.8 1.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3043) CpXC PF14353.1 CDI86588.1 - 7.2 6.5 11.6 8.9 6.2 1.8 2.2 2 0 0 2 2 2 0 CpXC protein DDRGK PF09756.4 CDI86588.1 - 7.3 5.9 23.5 4.5 6.6 5.1 2.1 2 0 0 2 2 2 0 DDRGK domain DUF2681 PF10883.3 CDI86588.1 - 8.1 6.7 26.3 2.5 8.3 5.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) DUF4652 PF15525.1 CDI86588.1 - 9.8 5.5 14.9 6.1 6.2 1.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4652) DUF3506 PF12014.3 CDI86588.1 - 9.8 5.9 9.2 1.1 9.0 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3506) SR-25 PF10500.4 CDI86589.1 - 0.0075 15.7 2.3 0.0075 15.7 1.6 1.2 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Ion_trans PF00520.26 CDI86592.1 - 2.8e-06 26.7 3.3 0.016 14.4 0.2 2.4 2 0 0 2 2 2 2 Ion transport protein Methyltransf_3 PF01596.12 CDI86593.1 - 1.6e-18 66.5 0.0 1.1e-09 37.6 0.0 2.3 2 0 0 2 2 2 2 O-methyltransferase Rhodanese PF00581.15 CDI86593.1 - 2e-11 44.1 0.0 4.9e-11 42.9 0.0 1.7 1 0 0 1 1 1 1 Rhodanese-like domain Methyltransf_24 PF13578.1 CDI86593.1 - 9.6e-09 36.0 0.1 2.2e-07 31.6 0.0 2.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 CDI86593.1 - 1.7e-05 25.3 0.0 4.7e-05 23.9 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 CDI86593.1 - 0.00077 19.4 0.3 0.0081 16.1 0.1 2.7 2 1 0 2 2 2 1 Methyltransferase domain tRNA_Me_trans PF03054.11 CDI86594.1 - 1.2e-76 257.6 0.0 3.6e-70 236.3 0.0 2.3 2 0 0 2 2 2 2 tRNA methyl transferase Asn_synthase PF00733.16 CDI86594.1 - 0.0058 16.1 0.0 0.0098 15.4 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase ThiI PF02568.9 CDI86594.1 - 0.0073 15.7 0.0 0.012 15.0 0.0 1.3 1 0 0 1 1 1 1 Thiamine biosynthesis protein (ThiI) CDC73 PF05179.9 CDI86594.1 - 0.24 10.7 0.1 0.46 9.7 0.0 1.3 1 0 0 1 1 1 0 RNA pol II accessory factor, Cdc73 family Carb_anhydrase PF00194.16 CDI86596.1 - 1.6e-12 46.9 1.4 8.6e-10 38.0 0.0 3.0 3 0 0 3 3 3 2 Eukaryotic-type carbonic anhydrase DUF387 PF04079.11 CDI86596.1 - 0.0055 16.0 0.0 0.011 15.0 0.0 1.5 1 0 0 1 1 1 1 Putative transcriptional regulators (Ypuh-like) MFS_1 PF07690.11 CDI86597.1 - 2.1e-10 39.8 23.6 6.9e-08 31.5 16.8 3.0 1 1 1 2 2 2 2 Major Facilitator Superfamily RAB3GAP2_N PF14655.1 CDI86599.1 - 0.23 10.4 3.7 0.31 10.0 2.5 1.1 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus PilM PF07419.7 CDI86599.1 - 0.29 10.6 3.4 0.43 10.0 2.4 1.2 1 0 0 1 1 1 0 PilM CwfJ_C_2 PF04676.9 CDI86600.1 - 8.8e-16 58.1 0.1 1.4e-15 57.5 0.0 1.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 CwfJ_C_1 PF04677.10 CDI86600.1 - 0.038 13.6 0.1 0.061 12.9 0.1 1.3 1 0 0 1 1 1 0 Protein similar to CwfJ C-terminus 1 PFO_beta_C PF12367.3 CDI86600.1 - 0.068 13.1 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 Pyruvate ferredoxin oxidoreductase beta subunit C terminal Suf PF05843.9 CDI86602.1 - 3.8 7.1 17.0 3.4 7.3 7.5 2.5 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) Herpes_UL87 PF03043.9 CDI86603.1 - 0.17 10.2 17.7 0.25 9.6 12.3 1.1 1 0 0 1 1 1 0 Herpesvirus UL87 family HATPase_c_2 PF13581.1 CDI86604.1 - 0.0079 15.9 6.9 0.0099 15.6 4.8 1.2 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain AAT PF03417.11 CDI86604.1 - 0.0083 15.5 12.8 0.0095 15.4 8.8 1.0 1 0 0 1 1 1 1 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase Shadoo PF14999.1 CDI86604.1 - 0.1 12.4 6.7 0.12 12.2 4.7 1.3 1 0 0 1 1 1 0 Shadow of prion protein, neuroprotective U79_P34 PF03064.11 CDI86604.1 - 0.12 11.9 9.1 0.12 11.8 6.3 1.0 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Spt20 PF12090.3 CDI86604.1 - 0.14 11.4 8.9 0.14 11.4 6.1 1.2 1 0 0 1 1 1 0 Spt20 family GidB PF02527.10 CDI86604.1 - 0.17 10.9 4.6 0.17 11.0 3.2 1.1 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G FimP PF09766.4 CDI86604.1 - 0.26 10.3 19.5 0.3 10.1 13.5 1.0 1 0 0 1 1 1 0 Fms-interacting protein DUF3408 PF11888.3 CDI86604.1 - 0.51 10.2 8.9 0.51 10.2 6.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) Toluene_X PF03349.11 CDI86604.1 - 0.74 8.1 8.8 0.79 8.0 6.1 1.0 1 0 0 1 1 1 0 Outer membrane protein transport protein (OMPP1/FadL/TodX) DUF4446 PF14584.1 CDI86604.1 - 0.94 9.2 7.5 1 9.1 5.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) Blt1 PF12754.2 CDI86604.1 - 1.1 8.8 12.4 1.1 8.7 8.6 1.0 1 0 0 1 1 1 0 Cell-cycle control medial ring component RAB3GAP2_N PF14655.1 CDI86604.1 - 1.1 8.1 10.0 1.3 7.9 7.0 1.1 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Band_3_cyto PF07565.8 CDI86604.1 - 1.8 8.0 7.7 1.7 8.0 5.3 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Dala_Dala_lig_N PF01820.16 CDI86604.1 - 2.6 8.3 6.2 2.9 8.2 4.3 1.2 1 0 0 1 1 1 0 D-ala D-ala ligase N-terminus DUF763 PF05559.6 CDI86604.1 - 2.6 6.9 7.3 2.6 6.8 5.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF763) Herpes_glycop PF01528.11 CDI86604.1 - 2.7 6.6 7.6 2.9 6.4 5.3 1.0 1 0 0 1 1 1 0 Herpesvirus glycoprotein M Peptidase_S49_N PF08496.5 CDI86604.1 - 3.2 7.5 11.4 3.8 7.3 7.9 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Serinc PF03348.10 CDI86604.1 - 4 6.0 10.8 4 6.0 7.5 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) DUF1676 PF07898.8 CDI86604.1 - 4.7 7.5 9.0 1.5 9.1 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1676) Corona_nucleoca PF00937.13 CDI86604.1 - 4.8 6.0 16.4 4.9 5.9 11.3 1.0 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein Med15 PF09606.5 CDI86604.1 - 5.2 5.1 31.3 5.9 4.9 21.7 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF2232 PF09991.4 CDI86604.1 - 5.3 5.9 5.4 6 5.7 3.7 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) OATP PF03137.15 CDI86604.1 - 5.3 4.9 6.0 5 5.0 4.2 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family DUF897 PF05982.7 CDI86604.1 - 5.3 5.7 6.1 5.6 5.6 4.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF897) DUF2235 PF09994.4 CDI86604.1 - 5.9 6.1 8.0 6.3 6.0 5.5 1.1 1 0 0 1 1 1 0 Uncharacterized alpha/beta hydrolase domain (DUF2235) Neur_chan_memb PF02932.11 CDI86604.1 - 8.5 6.1 6.8 8.5 6.1 4.7 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Suf PF05843.9 CDI86604.1 - 8.6 6.0 15.8 8.9 5.9 11.0 1.0 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) R_equi_Vir PF05526.6 CDI86604.1 - 9.3 5.8 13.8 11 5.6 9.6 1.1 1 0 0 1 1 1 0 Rhodococcus equi virulence-associated protein SR-25 PF10500.4 CDI86605.1 - 0.0015 18.0 5.4 0.0019 17.7 3.7 1.0 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Codanin-1_C PF15296.1 CDI86605.1 - 0.018 14.8 4.4 0.021 14.6 3.1 1.0 1 0 0 1 1 1 0 Codanin-1 C-terminus CAF-1_p150 PF11600.3 CDI86605.1 - 0.019 14.3 7.4 0.022 14.1 5.1 1.0 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Ten_N PF06484.7 CDI86605.1 - 0.034 13.2 4.8 0.036 13.1 3.3 1.0 1 0 0 1 1 1 0 Teneurin Intracellular Region SpoIIIAH PF12685.2 CDI86605.1 - 0.093 12.2 4.9 0.11 11.9 3.4 1.1 1 0 0 1 1 1 0 SpoIIIAH-like protein DUF2057 PF09829.4 CDI86605.1 - 0.15 11.7 11.1 0.18 11.4 7.7 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2057) ICL PF00463.16 CDI86605.1 - 0.17 10.0 1.7 0.2 9.8 1.2 1.0 1 0 0 1 1 1 0 Isocitrate lyase family CDK2AP PF09806.4 CDI86605.1 - 0.2 11.8 13.0 0.22 11.7 9.0 1.0 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein DUF1180 PF06679.7 CDI86605.1 - 0.24 11.2 3.7 0.24 11.2 2.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) FimP PF09766.4 CDI86605.1 - 0.37 9.8 6.4 0.42 9.6 4.5 1.0 1 0 0 1 1 1 0 Fms-interacting protein DOR PF14839.1 CDI86605.1 - 0.37 10.5 9.4 0.48 10.1 6.5 1.1 1 0 0 1 1 1 0 DOR family WWbp PF10349.4 CDI86605.1 - 0.41 11.5 5.8 0.46 11.3 4.1 1.1 1 0 0 1 1 1 0 WW-domain ligand protein Serinc PF03348.10 CDI86605.1 - 0.42 9.2 2.6 0.44 9.1 1.8 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) CDK5_activator PF03261.10 CDI86605.1 - 0.57 9.4 5.8 0.61 9.3 4.0 1.0 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein IncA PF04156.9 CDI86605.1 - 0.6 9.6 7.8 0.74 9.3 5.4 1.1 1 0 0 1 1 1 0 IncA protein PsbW PF07123.7 CDI86605.1 - 0.64 10.0 3.3 0.68 9.9 2.3 1.0 1 0 0 1 1 1 0 Photosystem II reaction centre W protein (PsbW) Spt20 PF12090.3 CDI86605.1 - 0.66 9.2 5.4 0.68 9.2 3.7 1.1 1 0 0 1 1 1 0 Spt20 family Bul1_C PF04426.7 CDI86605.1 - 0.68 9.0 4.7 0.82 8.8 3.3 1.0 1 0 0 1 1 1 0 Bul1 C terminus DUF2360 PF10152.4 CDI86605.1 - 1.1 9.5 8.2 1.1 9.5 5.7 1.1 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) Paramyxo_C PF01692.13 CDI86605.1 - 1.1 8.7 6.5 1.3 8.5 4.5 1.1 1 0 0 1 1 1 0 Paramyxovirus non-structural protein c BNIP3 PF06553.7 CDI86605.1 - 1.3 8.3 10.0 1.6 8.0 6.9 1.0 1 0 0 1 1 1 0 BNIP3 Senescence_reg PF04520.8 CDI86605.1 - 1.7 9.1 7.7 1.9 8.9 5.3 1.0 1 0 0 1 1 1 0 Senescence regulator Spore_coat_CotO PF14153.1 CDI86605.1 - 2 7.8 8.3 2.3 7.5 5.8 1.0 1 0 0 1 1 1 0 Spore coat protein CotO NUC194 PF08163.7 CDI86605.1 - 2.2 7.0 7.9 2.6 6.8 5.5 1.0 1 0 0 1 1 1 0 NUC194 domain zf-C4H2 PF10146.4 CDI86605.1 - 2.3 8.1 7.8 2.4 8.1 5.4 1.0 1 0 0 1 1 1 0 Zinc finger-containing protein Suf PF05843.9 CDI86605.1 - 2.7 7.6 8.6 3.1 7.4 6.0 1.0 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Presenilin PF01080.12 CDI86605.1 - 3.3 6.4 4.7 3.7 6.2 3.2 1.0 1 0 0 1 1 1 0 Presenilin Shisa PF13908.1 CDI86605.1 - 5.1 7.2 8.6 5.1 7.2 5.9 1.1 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Pex14_N PF04695.8 CDI86605.1 - 5.9 6.9 14.7 6.7 6.7 10.2 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region TFIID_20kDa PF03847.8 CDI86606.1 - 0.017 15.3 0.0 0.027 14.7 0.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A CENP-S PF15630.1 CDI86606.1 - 0.045 13.9 0.0 0.1 12.8 0.0 1.5 1 0 0 1 1 1 0 Kinetochore component CENP-S RAP1 PF07218.6 CDI86608.1 - 0.054 11.5 15.0 0.32 9.0 3.0 2.1 2 0 0 2 2 2 0 Rhoptry-associated protein 1 (RAP-1) AWPM-19 PF05512.6 CDI86608.1 - 0.34 10.9 0.0 0.34 10.9 0.0 3.2 4 0 0 4 4 4 0 AWPM-19-like family AAA_23 PF13476.1 CDI86609.1 - 0.0014 19.0 1.8 0.0017 18.6 1.2 1.2 1 0 0 1 1 1 1 AAA domain FLO_LFY PF01698.11 CDI86609.1 - 0.14 10.9 8.0 0.2 10.4 5.6 1.2 1 0 0 1 1 1 0 Floricaula / Leafy protein Med1 PF10744.4 CDI86609.1 - 0.17 10.6 7.9 0.23 10.1 5.5 1.2 1 0 0 1 1 1 0 Mediator of RNA polymerase II transcription subunit 1 AUX_IAA PF02309.11 CDI86609.1 - 0.19 11.4 8.2 0.052 13.3 3.2 1.8 2 0 0 2 2 2 0 AUX/IAA family Herpes_DNAp_acc PF04929.7 CDI86609.1 - 0.41 9.5 8.3 0.025 13.5 1.7 1.7 1 1 1 2 2 2 0 Herpes DNA replication accessory factor Pal1 PF08316.6 CDI86609.1 - 0.73 10.2 5.5 0.37 11.2 2.0 1.9 2 0 0 2 2 2 0 Pal1 cell morphology protein Peroxin-13_N PF04088.8 CDI86609.1 - 1.4 8.8 5.5 3.6 7.5 3.8 1.6 1 0 0 1 1 1 0 Peroxin 13, N-terminal region DUF2370 PF10176.4 CDI86609.1 - 1.7 7.9 8.9 0.39 10.0 3.4 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2370) FAM176 PF14851.1 CDI86609.1 - 1.8 8.2 5.1 4.3 7.0 3.5 1.6 1 0 0 1 1 1 0 FAM176 family EIIBC-GUT_N PF03612.9 CDI86609.1 - 2.2 7.8 9.2 2.4 7.7 5.2 1.9 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus PBP1_TM PF14812.1 CDI86609.1 - 2.3 8.5 5.0 4 7.8 3.5 1.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Band_3_cyto PF07565.8 CDI86609.1 - 2.3 7.6 12.7 4.6 6.6 8.8 1.4 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Glyco_transf_6 PF03414.8 CDI86609.1 - 7.1 4.9 8.8 3.6 5.9 4.5 1.5 2 0 0 2 2 2 0 Glycosyltransferase family 6 RED_N PF07808.8 CDI86609.1 - 7.2 5.7 19.0 12 5.0 13.1 1.3 1 0 0 1 1 1 0 RED-like protein N-terminal region Folate_carrier PF01770.13 CDI86609.1 - 7.7 4.9 7.0 11 4.3 4.8 1.2 1 0 0 1 1 1 0 Reduced folate carrier Eapp_C PF10238.4 CDI86609.1 - 9.2 6.1 17.0 0.58 10.0 8.2 1.6 2 0 0 2 2 2 0 E2F-associated phosphoprotein DUF572 PF04502.8 CDI86611.1 - 1.7 7.8 30.8 2.1 7.4 21.4 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) FAM60A PF15396.1 CDI86613.1 - 0.32 10.7 19.4 0.37 10.4 13.5 1.1 1 0 0 1 1 1 0 Protein Family FAM60A NPR3 PF03666.8 CDI86613.1 - 0.41 9.1 23.5 0.51 8.8 16.3 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF2126 PF09899.4 CDI86613.1 - 0.61 8.0 15.8 0.66 7.9 10.9 1.1 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) Senescence_reg PF04520.8 CDI86613.1 - 0.62 10.5 18.7 0.8 10.1 13.0 1.1 1 0 0 1 1 1 0 Senescence regulator Hid1 PF12722.2 CDI86613.1 - 1.2 6.7 30.6 1.3 6.5 21.2 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Raftlin PF15250.1 CDI86613.1 - 1.7 7.1 26.2 2 6.8 18.2 1.0 1 0 0 1 1 1 0 Raftlin GAGA_bind PF06217.7 CDI86613.1 - 1.8 8.4 29.3 2.1 8.2 20.3 1.0 1 0 0 1 1 1 0 GAGA binding protein-like family FLO_LFY PF01698.11 CDI86613.1 - 1.9 7.2 27.2 2.3 6.9 18.9 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein NARP1 PF12569.3 CDI86613.1 - 2 7.0 25.4 3.1 6.4 17.6 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DUF1510 PF07423.6 CDI86613.1 - 2.1 7.6 37.7 2.6 7.3 26.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) PPP4R2 PF09184.6 CDI86613.1 - 2.2 7.7 30.4 2.8 7.4 21.1 1.0 1 0 0 1 1 1 0 PPP4R2 Band_3_cyto PF07565.8 CDI86613.1 - 2.7 7.4 25.1 4.1 6.8 17.4 1.3 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Mem_trans PF03547.13 CDI86613.1 - 2.7 6.1 14.6 3.2 5.9 10.1 1.1 1 0 0 1 1 1 0 Membrane transport protein HD-ZIP_N PF04618.7 CDI86613.1 - 2.8 8.5 14.9 3.8 8.0 10.3 1.2 1 0 0 1 1 1 0 HD-ZIP protein N terminus DUF4045 PF13254.1 CDI86613.1 - 3.2 6.9 27.6 3.8 6.6 19.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) DUF3807 PF12720.2 CDI86613.1 - 3.8 7.6 34.2 5.1 7.2 23.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) Nha1_C PF08619.5 CDI86613.1 - 4.9 6.3 31.1 5.7 6.0 21.5 1.0 1 0 0 1 1 1 0 Alkali metal cation/H+ antiporter Nha1 C terminus BTV_NS2 PF04514.7 CDI86613.1 - 6.7 5.4 25.7 7.8 5.2 17.8 1.0 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 PIH1 PF08190.7 CDI86613.1 - 7.4 5.9 32.2 10 5.4 22.3 1.2 1 0 0 1 1 1 0 pre-RNA processing PIH1/Nop17 DUF4175 PF13779.1 CDI86613.1 - 7.6 4.0 65.0 9 3.8 45.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) GPCR_chapero_1 PF11904.3 CDI86613.1 - 8.4 5.4 24.6 9.2 5.2 17.1 1.0 1 0 0 1 1 1 0 GPCR-chaperone Neur_chan_memb PF02932.11 CDI86613.1 - 8.5 6.1 21.5 10 5.9 14.9 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DNA_pol_viral_N PF00242.12 CDI86613.1 - 8.8 5.2 23.7 10 5.0 16.4 1.0 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain DUF2146 PF10220.4 CDI86613.1 - 9.2 4.0 24.7 10 3.9 17.1 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2146) DUF966 PF06136.8 CDI86613.1 - 9.2 5.5 26.1 11 5.2 18.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) LicD PF04991.8 CDI86613.1 - 9.7 6.2 7.4 12 5.9 5.1 1.2 1 0 0 1 1 1 0 LicD family Sporozoite_P67 PF05642.6 CDI86614.1 - 0.00078 17.4 3.3 0.00078 17.4 2.3 1.6 2 0 0 2 2 2 1 Sporozoite P67 surface antigen IncA PF04156.9 CDI86614.1 - 0.014 15.0 22.4 0.2 11.2 2.4 2.4 2 0 0 2 2 2 0 IncA protein CDK2AP PF09806.4 CDI86614.1 - 0.019 15.2 24.5 0.34 11.1 9.5 2.3 2 0 0 2 2 2 0 Cyclin-dependent kinase 2-associated protein Serinc PF03348.10 CDI86614.1 - 0.034 12.8 7.7 0.63 8.6 1.6 2.2 2 0 0 2 2 2 0 Serine incorporator (Serinc) PAT1 PF09770.4 CDI86614.1 - 0.048 11.9 38.3 0.26 9.5 8.8 2.1 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 Neur_chan_memb PF02932.11 CDI86614.1 - 0.35 10.7 14.7 0.31 10.9 5.5 2.1 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region OSTbeta PF15048.1 CDI86614.1 - 0.36 10.9 7.9 0.2 11.7 1.9 2.3 2 0 0 2 2 2 0 Organic solute transporter subunit beta protein FHIPEP PF00771.15 CDI86614.1 - 0.51 8.5 7.5 2.5 6.3 1.5 2.1 2 0 0 2 2 2 0 FHIPEP family DUF4557 PF15101.1 CDI86614.1 - 0.9 9.3 28.3 1.7 8.4 9.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4557) OATP PF03137.15 CDI86614.1 - 1.5 6.7 7.5 8.1 4.3 0.1 2.2 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Peptidase_S49_N PF08496.5 CDI86614.1 - 1.9 8.2 15.5 0.86 9.3 4.8 2.2 2 0 0 2 2 2 0 Peptidase family S49 N-terminal MCLC PF05934.6 CDI86614.1 - 2.5 6.3 5.4 4.4 5.4 3.8 1.3 1 0 0 1 1 1 0 Mid-1-related chloride channel (MCLC) Folate_carrier PF01770.13 CDI86614.1 - 2.7 6.4 6.6 5.3 5.4 1.9 2.2 2 0 0 2 2 2 0 Reduced folate carrier FimP PF09766.4 CDI86614.1 - 2.7 6.9 32.2 3.4 6.6 11.3 2.2 2 0 0 2 2 2 0 Fms-interacting protein OmpH PF03938.9 CDI86614.1 - 3.8 7.4 42.6 1.4 8.8 14.2 2.2 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Spore_coat_CotO PF14153.1 CDI86614.1 - 4.3 6.7 21.9 1.9 7.9 6.3 2.3 2 0 0 2 2 2 0 Spore coat protein CotO DUF4199 PF13858.1 CDI86614.1 - 4.6 7.1 8.7 21 4.9 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4199) RAP1 PF07218.6 CDI86614.1 - 6.9 4.6 12.4 10 4.0 8.6 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) RP-C_C PF11800.3 CDI86615.1 - 1.6 8.3 4.1 2.3 7.8 2.9 1.4 1 1 0 1 1 1 0 Replication protein C C-terminal region Drc1-Sld2 PF11719.3 CDI86615.1 - 5.8 5.8 9.5 7.2 5.5 6.6 1.1 1 0 0 1 1 1 0 DNA replication and checkpoint protein DUF4557 PF15101.1 CDI86616.1 - 0.0085 15.9 7.5 0.0085 15.9 5.2 2.2 3 0 0 3 3 3 1 Domain of unknown function (DUF4557) Spt20 PF12090.3 CDI86616.1 - 0.0087 15.4 4.3 0.024 13.9 3.0 1.8 1 0 0 1 1 1 1 Spt20 family Suf PF05843.9 CDI86616.1 - 2.4 7.8 11.3 6.7 6.3 7.8 1.7 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Ank_2 PF12796.2 CDI86618.1 - 2.2e-19 69.5 0.0 1.9e-17 63.3 0.0 2.0 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 CDI86618.1 - 2.4e-19 68.0 0.3 2.2e-05 24.0 0.0 3.3 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.1 CDI86618.1 - 5.4e-18 64.6 0.2 1e-07 31.9 0.0 3.1 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 CDI86618.1 - 1.9e-12 47.3 0.0 4.4e-07 30.2 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 CDI86618.1 - 5.3e-11 41.6 0.0 0.0037 17.3 0.0 3.3 3 0 0 3 3 3 3 Ankyrin repeat AFP PF02420.10 CDI86618.1 - 0.74 10.1 4.8 2.1 8.7 3.3 1.8 1 0 0 1 1 1 0 Insect antifreeze protein repeat Med15 PF09606.5 CDI86620.1 - 0.039 12.1 54.9 0.048 11.8 38.0 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal CAF-1_p150 PF11600.3 CDI86620.1 - 0.68 9.2 26.3 0.79 9.0 18.2 1.0 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF4175 PF13779.1 CDI86620.1 - 1.4 6.5 38.9 1.5 6.4 27.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) DUF2215 PF10225.4 CDI86620.1 - 3.4 7.0 11.3 3.9 6.8 7.8 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) AAA_23 PF13476.1 CDI86620.1 - 9 6.5 18.6 10 6.3 12.9 1.1 1 0 0 1 1 1 0 AAA domain HAD_2 PF13419.1 CDI86621.1 - 0.046 13.9 0.0 2.7 8.2 0.0 2.2 1 1 1 2 2 2 0 Haloacid dehalogenase-like hydrolase DUF3801 PF12687.2 CDI86622.1 - 0.19 11.2 24.1 0.27 10.7 5.2 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3801) ETRAMP PF09716.5 CDI86622.1 - 0.49 10.3 0.1 0.49 10.3 0.0 4.8 4 2 0 4 4 4 0 Malarial early transcribed membrane protein (ETRAMP) DUF4483 PF14825.1 CDI86622.1 - 0.59 9.7 23.2 5.6 6.5 7.4 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4483) DUF4614 PF15391.1 CDI86623.1 - 1.4 8.6 30.4 0.78 9.4 0.3 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4614) Secretin_N_2 PF07655.8 CDI86623.1 - 3.2 8.2 54.0 0.87 10.0 1.6 3.2 3 0 0 3 3 3 0 Secretin N-terminal domain Ribosomal_60s PF00428.14 CDI86624.1 - 0.014 15.7 8.7 0.019 15.3 6.1 1.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein Ribonuc_red_lgC PF02867.10 CDI86624.1 - 0.04 12.4 4.2 0.043 12.3 2.9 1.0 1 0 0 1 1 1 0 Ribonucleotide reductase, barrel domain DUF4316 PF14195.1 CDI86624.1 - 0.087 12.9 7.9 0.69 10.0 1.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4316) Glyco_hydro_71 PF03659.9 CDI86624.1 - 0.22 9.9 6.6 0.057 11.8 2.1 1.7 1 1 1 2 2 2 0 Glycosyl hydrolase family 71 Nop53 PF07767.6 CDI86624.1 - 3.5 6.5 20.9 4 6.3 14.5 1.0 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) DUF3801 PF12687.2 CDI86624.1 - 9.5 5.7 14.7 5.6 6.4 2.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3801) ASFV_J13L PF05568.6 CDI86624.1 - 9.8 5.6 12.9 1.5 8.3 6.7 1.4 1 1 0 1 1 1 0 African swine fever virus J13L protein Vps54 PF07928.7 CDI86625.1 - 1.1e-05 25.6 3.1 1.1e-05 25.6 2.2 3.3 3 0 0 3 3 3 1 Vps54-like protein Myco_19_kDa PF05481.7 CDI86626.1 - 0.76 9.5 5.2 1.1 9.0 3.6 1.2 1 0 0 1 1 1 0 Mycobacterium 19 kDa lipoprotein antigen SR-25 PF10500.4 CDI86627.1 - 0.33 10.3 17.0 0.38 10.1 11.8 1.0 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein AIF_C PF14721.1 CDI86627.1 - 0.47 10.7 15.1 0.62 10.3 10.5 1.2 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term PBP1_TM PF14812.1 CDI86627.1 - 0.61 10.4 10.5 0.87 9.9 7.3 1.2 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Peptidase_S49_N PF08496.5 CDI86627.1 - 0.89 9.3 19.6 1.3 8.7 13.6 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Zip PF02535.17 CDI86627.1 - 1.4 7.8 14.5 1.6 7.6 10.0 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter FYDLN_acid PF09538.5 CDI86627.1 - 2 9.0 11.4 2.5 8.7 7.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) Raftlin PF15250.1 CDI86627.1 - 2.7 6.4 21.1 3.1 6.2 14.6 1.0 1 0 0 1 1 1 0 Raftlin GAGA_bind PF06217.7 CDI86627.1 - 2.8 7.8 20.9 3 7.7 14.5 1.0 1 0 0 1 1 1 0 GAGA binding protein-like family SpoVR PF04293.8 CDI86627.1 - 3.4 5.9 21.8 3.6 5.8 15.1 1.0 1 0 0 1 1 1 0 SpoVR like protein RIC3 PF15361.1 CDI86627.1 - 3.4 7.8 20.5 4.2 7.5 14.2 1.2 1 0 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 UPF0565 PF10561.4 CDI86627.1 - 4.2 6.1 15.3 4.4 6.0 10.6 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0565 YqfQ PF14181.1 CDI86627.1 - 4.6 7.2 24.9 5.6 6.9 17.3 1.1 1 0 0 1 1 1 0 YqfQ-like protein RR_TM4-6 PF06459.7 CDI86627.1 - 5.4 6.8 21.3 6.2 6.6 14.8 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DDHD PF02862.12 CDI86627.1 - 5.5 6.7 23.4 6.5 6.4 16.2 1.0 1 0 0 1 1 1 0 DDHD domain DUF913 PF06025.7 CDI86627.1 - 5.8 5.5 12.1 6.2 5.4 8.4 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DUF702 PF05142.7 CDI86627.1 - 6.2 6.9 19.9 7.6 6.6 13.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF702) Tim54 PF11711.3 CDI86627.1 - 6.2 5.2 15.1 7 5.1 10.5 1.0 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 NARP1 PF12569.3 CDI86627.1 - 6.9 5.3 23.1 7.8 5.1 16.0 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Glyco_transf_15 PF01793.11 CDI86627.1 - 6.9 5.5 21.1 7.3 5.4 14.6 1.0 1 0 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase FAM60A PF15396.1 CDI86627.1 - 7.2 6.2 18.6 7.9 6.1 12.9 1.1 1 0 0 1 1 1 0 Protein Family FAM60A CKAP2_C PF15297.1 CDI86627.1 - 7.3 5.2 22.7 8.4 5.0 15.7 1.0 1 0 0 1 1 1 0 Cytoskeleton-associated protein 2 C-terminus RNA_pol_Rpb1_5 PF04998.12 CDI86627.1 - 7.8 5.6 15.4 8.1 5.6 10.7 1.0 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 DUF3449 PF11931.3 CDI86627.1 - 7.8 5.9 22.0 9 5.7 15.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3449) Serinc PF03348.10 CDI86627.1 - 8.5 4.9 21.0 9.4 4.8 14.5 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) DUF1253 PF06862.7 CDI86628.1 - 2e-06 26.4 0.0 2e-06 26.4 0.0 2.5 3 0 0 3 3 3 1 Protein of unknown function (DUF1253) DUF2201_N PF13203.1 CDI86628.1 - 0.0041 16.3 18.6 0.0041 16.3 12.9 2.2 2 0 0 2 2 2 1 Putative metallopeptidase domain Spore_coat_CotO PF14153.1 CDI86628.1 - 0.58 9.5 22.1 0.14 11.5 7.6 2.3 2 0 0 2 2 2 0 Spore coat protein CotO UPF0052 PF01933.13 CDI86628.1 - 1.4 8.2 7.0 2.4 7.3 4.9 1.3 1 0 0 1 1 1 0 Uncharacterised protein family UPF0052 RP-C_C PF11800.3 CDI86628.1 - 2.3 7.8 25.3 0.31 10.7 5.4 2.7 2 0 0 2 2 2 0 Replication protein C C-terminal region PIH1 PF08190.7 CDI86628.1 - 2.8 7.3 24.9 0.28 10.5 7.3 2.1 2 0 0 2 2 2 0 pre-RNA processing PIH1/Nop17 N6_N4_Mtase PF01555.13 CDI86628.1 - 3.6 7.0 10.4 0.027 13.9 1.5 1.6 2 0 0 2 2 2 0 DNA methylase DUF2052 PF09747.4 CDI86628.1 - 9.6 6.0 24.6 0.16 11.8 6.8 2.3 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) ArfGap PF01412.13 CDI86630.1 - 1.7e-23 82.6 0.1 4.9e-23 81.1 0.0 1.8 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf Topoisom_bac PF01131.15 CDI86630.1 - 3.2e-07 29.5 0.0 4.6e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 DNA topoisomerase TFIIA PF03153.8 CDI86630.1 - 1.2 8.9 12.9 1.7 8.4 8.9 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Macoilin PF09726.4 CDI86630.1 - 2.6 6.2 11.0 3.8 5.6 7.7 1.2 1 0 0 1 1 1 0 Transmembrane protein E1-E2_ATPase PF00122.15 CDI86631.1 - 2.6e-25 88.8 2.4 9.3e-16 57.5 0.0 3.3 2 1 1 3 3 3 2 E1-E2 ATPase Hydrolase PF00702.21 CDI86631.1 - 5.7e-20 72.6 0.0 7.3e-19 69.0 0.0 2.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 CDI86631.1 - 1.8e-11 44.5 0.2 8.2e-10 39.1 0.1 3.2 3 1 0 3 3 3 1 haloacid dehalogenase-like hydrolase HMA PF00403.21 CDI86631.1 - 1.7e-08 34.4 0.0 3.1e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 Heavy-metal-associated domain Zea_mays_MuDR PF05928.6 CDI86631.1 - 0.014 14.7 0.2 0.038 13.4 0.1 1.6 1 0 0 1 1 1 0 Zea mays MURB-like protein (MuDR) Hydrolase_3 PF08282.7 CDI86631.1 - 0.18 11.3 0.0 2.5 7.6 0.0 2.1 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase COX2_TM PF02790.10 CDI86632.1 - 0.013 15.4 1.9 0.013 15.4 1.3 2.8 3 0 0 3 3 3 0 Cytochrome C oxidase subunit II, transmembrane domain Phage_Coat_B PF05356.6 CDI86632.1 - 0.026 14.2 0.6 5.4 6.7 0.1 3.4 2 0 0 2 2 2 0 Phage Coat protein B Wzy_C PF04932.10 CDI86632.1 - 0.13 12.0 4.5 0.13 12.0 0.3 2.6 3 0 0 3 3 3 0 O-Antigen ligase Abhydrolase_6 PF12697.2 CDI86633.1 - 4.3e-26 92.2 0.4 7.9e-26 91.3 0.3 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CDI86633.1 - 1.3e-10 41.1 0.1 3.9e-10 39.6 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CDI86633.1 - 3.8e-05 23.3 0.1 0.008 15.7 0.0 3.0 3 0 0 3 3 3 1 alpha/beta hydrolase fold PGAP1 PF07819.8 CDI86633.1 - 0.00036 20.2 0.4 0.00059 19.4 0.3 1.2 1 0 0 1 1 1 1 PGAP1-like protein Lipase_3 PF01764.20 CDI86633.1 - 0.021 14.4 0.3 0.036 13.6 0.2 1.3 1 0 0 1 1 1 0 Lipase (class 3) Hydrolase_4 PF12146.3 CDI86633.1 - 0.027 14.3 0.0 0.055 13.3 0.0 1.5 1 0 0 1 1 1 0 Putative lysophospholipase Thioesterase PF00975.15 CDI86633.1 - 0.09 12.9 0.4 0.4 10.8 0.1 2.3 3 0 0 3 3 3 0 Thioesterase domain Dynein_heavy PF03028.10 CDI86634.1 - 3.6e-161 537.6 1.9 9.2e-83 278.5 0.0 4.3 4 1 1 5 5 4 3 Dynein heavy chain and region D6 of dynein motor AAA_6 PF12774.2 CDI86634.1 - 1.5e-110 368.2 0.0 2.5e-110 367.4 0.0 1.4 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region D1 AAA_8 PF12780.2 CDI86634.1 - 1.5e-100 335.5 0.0 2.8e-100 334.6 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 DHC_N2 PF08393.8 CDI86634.1 - 1.9e-88 296.7 8.8 1.9e-88 296.7 6.1 3.3 4 1 0 4 4 4 1 Dynein heavy chain, N-terminal region 2 MT PF12777.2 CDI86634.1 - 1.7e-77 260.5 14.0 4.2e-77 259.2 9.7 1.8 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_7 PF12775.2 CDI86634.1 - 1.9e-37 128.8 0.4 2.6e-35 121.8 0.1 2.7 1 1 1 2 2 2 1 P-loop containing dynein motor region D3 AAA_9 PF12781.2 CDI86634.1 - 2.2e-28 98.6 5.1 1.1e-17 63.6 0.1 3.4 1 1 1 3 3 3 2 ATP-binding dynein motor region D5 AAA_5 PF07728.9 CDI86634.1 - 3.3e-20 72.2 0.0 2.9e-10 39.9 0.0 6.1 5 1 0 5 5 5 2 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 CDI86634.1 - 1.3e-06 29.2 0.3 0.053 14.3 0.0 3.5 3 0 0 3 3 2 2 AAA domain TIG PF01833.19 CDI86634.1 - 1.6e-06 28.0 0.0 4.7e-06 26.4 0.0 1.7 1 0 0 1 1 1 1 IPT/TIG domain AAA_18 PF13238.1 CDI86634.1 - 2.9e-05 24.3 0.0 0.11 12.7 0.0 3.4 2 0 0 2 2 2 2 AAA domain Kelch_5 PF13854.1 CDI86634.1 - 4.3e-05 23.3 0.0 3.7 7.5 0.0 3.8 3 0 0 3 3 3 1 Kelch motif AAA PF00004.24 CDI86634.1 - 0.00083 19.5 0.1 0.27 11.4 0.0 3.4 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 CDI86634.1 - 0.00098 19.2 0.7 9.5 6.3 0.0 5.3 5 0 0 5 5 5 0 AAA domain AAA_33 PF13671.1 CDI86634.1 - 0.02 14.7 1.0 3.8 7.3 0.0 3.1 3 0 0 3 3 2 0 AAA domain ArgK PF03308.11 CDI86634.1 - 0.025 13.3 0.0 0.22 10.2 0.0 2.4 2 0 0 2 2 2 0 ArgK protein AAA_10 PF12846.2 CDI86634.1 - 0.069 12.5 1.3 0.41 10.0 0.0 2.8 3 0 0 3 3 3 0 AAA-like domain RNA_helicase PF00910.17 CDI86634.1 - 0.08 13.1 0.2 12 6.1 0.0 3.3 3 0 0 3 3 3 0 RNA helicase AAA_19 PF13245.1 CDI86634.1 - 0.14 11.8 2.3 1.7 8.4 0.1 3.6 3 0 0 3 3 3 0 Part of AAA domain Kelch_6 PF13964.1 CDI86634.1 - 0.18 12.0 0.0 9 6.6 0.0 3.1 3 0 0 3 3 2 0 Kelch motif Reo_sigmaC PF04582.7 CDI86634.1 - 0.21 10.7 15.4 1.3 8.1 1.7 3.9 4 0 0 4 4 4 0 Reovirus sigma C capsid protein Kelch_1 PF01344.20 CDI86634.1 - 0.21 11.1 0.0 0.81 9.2 0.0 2.0 2 0 0 2 2 2 0 Kelch motif Fer4_18 PF13746.1 CDI86635.1 - 0.11 12.9 0.2 0.32 11.4 0.2 1.8 1 0 0 1 1 1 0 4Fe-4S dicluster domain ClpS PF02617.12 CDI86635.1 - 0.12 12.1 0.4 0.28 10.9 0.3 1.6 1 0 0 1 1 1 0 ATP-dependent Clp protease adaptor protein ClpS Phostensin_N PF13916.1 CDI86635.1 - 6.4 6.8 6.3 11 6.0 4.4 1.4 1 0 0 1 1 1 0 PP1-regulatory protein, Phostensin N-terminal ATP_bind_3 PF01171.15 CDI86636.1 - 5.3e-15 55.3 32.5 9.4e-08 31.7 4.5 5.2 3 2 3 6 6 6 4 PP-loop family LANC_like PF05147.8 CDI86638.1 - 0.0003 19.4 1.2 0.00031 19.4 0.0 1.5 2 0 0 2 2 2 1 Lanthionine synthetase C-like protein SR-25 PF10500.4 CDI86638.1 - 0.0019 17.7 7.1 0.0019 17.7 4.9 1.7 3 0 0 3 3 2 1 Nuclear RNA-splicing-associated protein CDC45 PF02724.9 CDI86638.1 - 0.002 16.2 3.3 0.002 16.2 2.3 1.2 1 0 0 1 1 1 1 CDC45-like protein Ycf1 PF05758.7 CDI86638.1 - 0.0049 14.6 0.1 0.0049 14.6 0.1 1.0 1 0 0 1 1 1 1 Ycf1 SAPS PF04499.10 CDI86638.1 - 0.041 12.5 4.6 0.049 12.2 3.2 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein AAA_23 PF13476.1 CDI86638.1 - 0.078 13.2 7.3 0.1 12.8 5.1 1.2 1 0 0 1 1 1 0 AAA domain SPX PF03105.14 CDI86638.1 - 0.1 12.3 7.3 0.12 12.1 5.1 1.1 1 0 0 1 1 1 0 SPX domain Hid1 PF12722.2 CDI86638.1 - 0.12 9.9 6.8 0.14 9.7 4.7 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein IncFII_repA PF02387.10 CDI86638.1 - 0.13 11.4 3.6 0.17 11.0 2.5 1.1 1 0 0 1 1 1 0 IncFII RepA protein family PLRV_ORF5 PF01690.12 CDI86638.1 - 0.14 11.2 7.9 0.16 11.0 5.5 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Neur_chan_memb PF02932.11 CDI86638.1 - 0.29 10.9 3.8 0.33 10.7 2.6 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Presenilin PF01080.12 CDI86638.1 - 0.34 9.6 5.2 0.47 9.2 3.6 1.2 1 0 0 1 1 1 0 Presenilin Mcm10 PF09332.6 CDI86638.1 - 0.42 9.9 10.6 0.56 9.4 7.3 1.3 1 0 0 1 1 1 0 Mcm10 replication factor PHD_3 PF13922.1 CDI86638.1 - 0.48 10.7 21.7 0.61 10.3 3.8 2.4 2 0 0 2 2 2 0 PHD domain of transcriptional enhancer, Asx FHIPEP PF00771.15 CDI86638.1 - 1 7.5 4.0 1.5 7.0 2.8 1.2 1 0 0 1 1 1 0 FHIPEP family FAM60A PF15396.1 CDI86638.1 - 3.6 7.2 12.0 5.4 6.7 8.3 1.2 1 0 0 1 1 1 0 Protein Family FAM60A Pox_RNA_Pol_19 PF05320.7 CDI86638.1 - 4.7 6.9 8.5 8.8 6.0 5.9 1.4 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit DUF3506 PF12014.3 CDI86638.1 - 5.3 6.8 8.4 8.3 6.2 0.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3506) Spore_YhcN_YlaJ PF09580.5 CDI86638.1 - 5.3 7.1 10.6 9.2 6.3 7.4 1.3 1 0 0 1 1 1 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) UPF0564 PF10595.4 CDI86638.1 - 5.7 5.7 25.9 8.3 5.2 18.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0564 DivIC PF04977.10 CDI86638.1 - 6 6.4 19.9 1.1 8.7 1.8 2.2 2 0 0 2 2 2 0 Septum formation initiator Rpp20 PF12328.3 CDI86638.1 - 8.1 6.0 10.2 3.6 7.2 0.5 2.3 2 0 0 2 2 2 0 Rpp20 subunit of nuclear RNase MRP and P RRN9 PF10680.4 CDI86638.1 - 8.4 6.2 6.6 23 4.7 0.3 2.4 2 0 0 2 2 2 0 RNA polymerase I specific transcription initiation factor DUF3812 PF12757.2 CDI86641.1 - 0.034 14.1 9.5 0.034 14.1 6.6 3.3 2 1 0 2 2 1 0 Protein of unknown function (DUF3812) DUF1510 PF07423.6 CDI86641.1 - 0.064 12.6 40.4 0.08 12.2 17.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) Utp14 PF04615.8 CDI86641.1 - 0.11 10.6 39.0 0.16 10.1 27.0 1.2 1 0 0 1 1 1 0 Utp14 protein Hid1 PF12722.2 CDI86641.1 - 0.7 7.4 40.9 0.88 7.1 28.4 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein CAF-1_p150 PF11600.3 CDI86641.1 - 0.8 9.0 46.4 0.46 9.8 19.7 2.1 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Rtf2 PF04641.7 CDI86641.1 - 1.4 8.0 36.7 0.91 8.6 15.7 2.0 2 0 0 2 2 2 0 Rtf2 RING-finger DUF4512 PF14975.1 CDI86641.1 - 6 7.7 26.8 8.4 7.2 10.3 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4512) Daxx PF03344.10 CDI86641.1 - 6.5 5.1 37.5 8.4 4.7 26.0 1.1 1 0 0 1 1 1 0 Daxx Family FLO_LFY PF01698.11 CDI86641.1 - 6.5 5.4 37.5 2.7 6.7 15.4 2.1 2 0 0 2 2 2 0 Floricaula / Leafy protein Herpes_env PF01673.13 CDI86641.1 - 7.5 4.9 28.2 11 4.4 19.6 1.2 1 0 0 1 1 1 0 Herpesvirus putative major envelope glycoprotein Herpes_UL87 PF03043.9 CDI86641.1 - 9 4.5 25.0 10 4.3 17.3 1.0 1 0 0 1 1 1 0 Herpesvirus UL87 family DUF4207 PF13904.1 CDI86642.1 - 0.0025 17.2 33.5 0.0036 16.7 23.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4207) CAF-1_p150 PF11600.3 CDI86642.1 - 0.004 16.5 31.1 0.0049 16.2 21.6 1.1 1 0 0 1 1 1 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal SprA-related PF12118.3 CDI86642.1 - 0.005 16.2 48.2 0.0062 15.9 33.4 1.0 1 0 0 1 1 1 1 SprA-related family Raftlin PF15250.1 CDI86642.1 - 0.46 8.9 21.8 0.62 8.5 15.1 1.1 1 0 0 1 1 1 0 Raftlin RR_TM4-6 PF06459.7 CDI86642.1 - 0.71 9.7 21.0 0.93 9.3 14.6 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Apt1 PF10351.4 CDI86642.1 - 1.2 7.9 21.9 1.7 7.4 15.2 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain FLO_LFY PF01698.11 CDI86642.1 - 1.3 7.8 19.9 1.6 7.4 13.8 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein HemX PF04375.9 CDI86642.1 - 1.3 7.5 26.2 1.5 7.3 18.2 1.2 1 0 0 1 1 1 0 HemX Peptidase_S15 PF02129.13 CDI86642.1 - 1.5 8.1 13.5 1.8 7.8 9.4 1.2 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) DUF4011 PF13195.1 CDI86642.1 - 1.7 8.6 11.3 2.6 8.0 7.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4011) AAA_23 PF13476.1 CDI86642.1 - 1.7 8.9 18.5 2.1 8.6 12.8 1.1 1 0 0 1 1 1 0 AAA domain Med15 PF09606.5 CDI86642.1 - 2.1 6.4 63.5 2.7 6.0 44.0 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Hex_IIIa PF02455.11 CDI86642.1 - 2.5 6.6 18.0 3 6.4 12.5 1.0 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) SOBP PF15279.1 CDI86642.1 - 2.6 8.3 30.2 3.1 8.0 20.9 1.0 1 0 0 1 1 1 0 Sine oculis-binding protein eIF-3_zeta PF05091.7 CDI86642.1 - 3.2 6.2 25.8 3.9 5.9 17.9 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) PAT1 PF09770.4 CDI86642.1 - 3.8 5.6 54.0 5 5.2 37.4 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SID-1_RNA_chan PF13965.1 CDI86642.1 - 4 5.4 10.5 4.2 5.4 7.3 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 TFIIA PF03153.8 CDI86642.1 - 5.1 6.8 46.3 6.2 6.6 32.1 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SR-25 PF10500.4 CDI86642.1 - 6.8 6.1 41.9 2.2 7.7 13.0 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein PBP1_TM PF14812.1 CDI86642.1 - 7 7.0 14.5 0.61 10.4 5.0 2.1 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Pox_RNA_Pol_19 PF05320.7 CDI86642.1 - 7.5 6.2 14.2 0.19 11.4 3.9 1.9 2 0 0 2 2 2 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit HCO3_cotransp PF00955.16 CDI86642.1 - 8.3 4.9 6.9 10 4.6 4.8 1.1 1 0 0 1 1 1 0 HCO3- transporter family DUF3135 PF11333.3 CDI86643.1 - 0.024 14.8 0.3 0.024 14.8 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3135) Draxin PF15550.1 CDI86643.1 - 0.23 11.0 18.5 0.013 15.1 4.3 2.1 2 0 0 2 2 2 0 Draxin DUF4551 PF15087.1 CDI86643.1 - 2.3 6.4 23.9 3.5 5.8 16.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Herpes_capsid PF06112.6 CDI86643.1 - 5.1 7.1 53.7 1.9 8.4 7.8 3.3 3 0 0 3 3 3 0 Gammaherpesvirus capsid protein TFIIA PF03153.8 CDI86644.1 - 2.7 7.7 8.4 3.4 7.4 5.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Phage_lysis PF03245.8 CDI86644.1 - 3.6 7.5 7.3 0.78 9.7 2.9 1.5 2 0 0 2 2 2 0 Bacteriophage Rz lysis protein Menin PF05053.8 CDI86644.1 - 3.6 5.6 10.5 4.3 5.3 7.3 1.0 1 0 0 1 1 1 0 Menin DUF605 PF04652.11 CDI86644.1 - 4.2 6.6 16.3 5.1 6.4 11.3 1.1 1 0 0 1 1 1 0 Vta1 like Macoilin PF09726.4 CDI86644.1 - 5.7 5.0 20.1 6.9 4.8 13.9 1.1 1 0 0 1 1 1 0 Transmembrane protein RAP1 PF07218.6 CDI86645.1 - 1.5 6.8 13.5 1.7 6.6 9.4 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Pro-rich PF15240.1 CDI86646.1 - 0.00052 20.1 56.1 0.00052 20.1 38.9 5.3 2 2 3 5 5 5 2 Proline-rich Pex14_N PF04695.8 CDI86647.1 - 0.0009 19.3 21.0 0.001 19.1 14.6 1.1 1 0 0 1 1 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region FimP PF09766.4 CDI86647.1 - 0.0045 16.1 24.4 0.0069 15.4 16.9 1.3 1 0 0 1 1 1 1 Fms-interacting protein DUF1510 PF07423.6 CDI86647.1 - 0.0085 15.4 12.6 0.0096 15.3 8.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) TRAP_alpha PF03896.11 CDI86647.1 - 0.015 14.3 1.6 0.015 14.2 1.1 1.0 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Ctr PF04145.10 CDI86647.1 - 0.021 14.8 8.3 0.022 14.7 5.8 1.1 1 0 0 1 1 1 0 Ctr copper transporter family DUF4557 PF15101.1 CDI86647.1 - 0.028 14.2 24.6 0.031 14.1 17.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) AAA_11 PF13086.1 CDI86647.1 - 0.042 13.4 16.1 0.044 13.3 11.1 1.0 1 0 0 1 1 1 0 AAA domain DDHD PF02862.12 CDI86647.1 - 0.065 13.0 12.9 0.077 12.7 8.9 1.2 1 0 0 1 1 1 0 DDHD domain OATP PF03137.15 CDI86647.1 - 0.068 11.2 10.9 0.081 10.9 7.5 1.2 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family MSA-2c PF12238.3 CDI86647.1 - 0.069 12.8 10.3 0.083 12.5 7.2 1.1 1 0 0 1 1 1 0 Merozoite surface antigen 2c eIF-3_zeta PF05091.7 CDI86647.1 - 0.077 11.6 19.8 0.08 11.5 13.7 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) MecA PF05389.7 CDI86647.1 - 0.085 12.3 11.4 0.088 12.3 7.9 1.0 1 0 0 1 1 1 0 Negative regulator of genetic competence (MecA) PAT1 PF09770.4 CDI86647.1 - 0.086 11.0 40.4 0.092 10.9 28.0 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF2561 PF10812.3 CDI86647.1 - 0.09 12.3 2.0 0.097 12.2 1.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2561) DUF4366 PF14283.1 CDI86647.1 - 0.092 12.1 6.0 0.12 11.7 4.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) Serinc PF03348.10 CDI86647.1 - 0.1 11.2 12.4 0.11 11.1 8.6 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) Raftlin PF15250.1 CDI86647.1 - 0.11 10.9 16.6 0.12 10.8 11.5 1.0 1 0 0 1 1 1 0 Raftlin FAM176 PF14851.1 CDI86647.1 - 0.13 11.9 7.7 0.18 11.4 5.3 1.3 1 0 0 1 1 1 0 FAM176 family RR_TM4-6 PF06459.7 CDI86647.1 - 0.13 12.1 13.2 0.14 12.0 9.2 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 RIC3 PF15361.1 CDI86647.1 - 0.13 12.4 14.5 0.17 12.0 10.0 1.1 1 0 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 GAGA_bind PF06217.7 CDI86647.1 - 0.14 12.1 12.6 0.15 11.9 8.7 1.0 1 0 0 1 1 1 0 GAGA binding protein-like family DUF4446 PF14584.1 CDI86647.1 - 0.14 11.9 7.3 0.17 11.7 5.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) FemAB PF02388.11 CDI86647.1 - 0.15 10.7 13.9 0.16 10.6 9.6 1.0 1 0 0 1 1 1 0 FemAB family Tim54 PF11711.3 CDI86647.1 - 0.15 10.6 9.5 0.16 10.5 6.6 1.0 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 YfhO PF09586.5 CDI86647.1 - 0.15 10.0 10.2 0.16 9.9 7.0 1.0 1 0 0 1 1 1 0 Bacterial membrane protein YfhO Hom_end_hint PF05203.11 CDI86647.1 - 0.16 11.6 12.6 0.2 11.3 8.7 1.0 1 0 0 1 1 1 0 Hom_end-associated Hint DUF2370 PF10176.4 CDI86647.1 - 0.17 11.2 6.3 0.2 10.9 4.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) SpoIIP PF07454.6 CDI86647.1 - 0.17 11.0 10.8 0.19 10.9 7.5 1.0 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Rtf2 PF04641.7 CDI86647.1 - 0.17 11.0 13.5 0.19 10.8 9.3 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger DUF1800 PF08811.6 CDI86647.1 - 0.2 10.5 19.5 0.22 10.4 13.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1800) Peptidase_S49_N PF08496.5 CDI86647.1 - 0.21 11.3 15.2 0.3 10.8 10.5 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Ycf1 PF05758.7 CDI86647.1 - 0.21 9.2 15.3 0.21 9.2 10.6 1.0 1 0 0 1 1 1 0 Ycf1 FHIPEP PF00771.15 CDI86647.1 - 0.24 9.6 7.1 0.32 9.2 4.9 1.3 1 0 0 1 1 1 0 FHIPEP family DUF913 PF06025.7 CDI86647.1 - 0.25 10.0 9.8 0.28 9.8 6.8 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DUF4045 PF13254.1 CDI86647.1 - 0.26 10.5 12.3 0.26 10.5 8.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Folate_carrier PF01770.13 CDI86647.1 - 0.31 9.4 8.8 0.32 9.4 6.1 1.1 1 0 0 1 1 1 0 Reduced folate carrier Pap_E4 PF02711.9 CDI86647.1 - 0.33 11.8 12.7 0.43 11.4 8.8 1.3 1 0 0 1 1 1 0 E4 protein TFIIA PF03153.8 CDI86647.1 - 0.33 10.8 29.5 0.35 10.7 20.4 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PIH1 PF08190.7 CDI86647.1 - 0.34 10.3 19.4 0.38 10.1 13.5 1.0 1 0 0 1 1 1 0 pre-RNA processing PIH1/Nop17 MRI PF15325.1 CDI86647.1 - 0.39 11.7 4.4 0.55 11.2 3.0 1.3 1 0 0 1 1 1 0 Modulator of retrovirus infection AUX_IAA PF02309.11 CDI86647.1 - 0.4 10.4 11.3 0.43 10.2 7.8 1.1 1 0 0 1 1 1 0 AUX/IAA family Gag_spuma PF03276.9 CDI86647.1 - 0.43 8.8 33.1 0.49 8.6 23.0 1.0 1 0 0 1 1 1 0 Spumavirus gag protein NARP1 PF12569.3 CDI86647.1 - 0.43 9.2 15.7 0.5 9.0 10.9 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 UPF0565 PF10561.4 CDI86647.1 - 0.43 9.4 10.7 0.52 9.1 7.4 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0565 SID-1_RNA_chan PF13965.1 CDI86647.1 - 0.44 8.6 7.7 0.44 8.6 5.3 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Sugar_tr PF00083.19 CDI86647.1 - 0.46 9.0 2.2 0.47 8.9 1.5 1.1 1 0 0 1 1 1 0 Sugar (and other) transporter DUF2203 PF09969.4 CDI86647.1 - 0.46 10.6 10.5 0.6 10.3 7.3 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) Mem_trans PF03547.13 CDI86647.1 - 0.47 8.6 6.9 0.49 8.6 4.8 1.1 1 0 0 1 1 1 0 Membrane transport protein Zip PF02535.17 CDI86647.1 - 0.49 9.3 6.4 0.53 9.2 4.4 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter DUF3260 PF11658.3 CDI86647.1 - 0.5 8.4 13.0 0.53 8.3 9.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3260) Pal1 PF08316.6 CDI86647.1 - 0.56 10.6 6.3 0.61 10.5 4.4 1.1 1 0 0 1 1 1 0 Pal1 cell morphology protein Hid1 PF12722.2 CDI86647.1 - 0.56 7.8 16.6 0.59 7.7 11.5 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Neur_chan_memb PF02932.11 CDI86647.1 - 0.57 10.0 11.2 0.6 9.9 7.7 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Peptidase_U57 PF05582.7 CDI86647.1 - 0.59 9.0 11.7 0.6 9.0 8.1 1.1 1 0 0 1 1 1 0 YabG peptidase U57 R_equi_Vir PF05526.6 CDI86647.1 - 0.59 9.7 4.0 0.67 9.5 2.8 1.2 1 0 0 1 1 1 0 Rhodococcus equi virulence-associated protein FLO_LFY PF01698.11 CDI86647.1 - 0.61 8.8 16.8 0.69 8.6 11.6 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein Pneumo_phosprot PF02478.11 CDI86647.1 - 0.61 9.5 3.4 0.64 9.5 2.4 1.0 1 0 0 1 1 1 0 Pneumovirus phosphoprotein Baculo_PP31 PF05311.6 CDI86647.1 - 0.65 9.2 15.2 0.75 9.0 10.6 1.1 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) DUF4337 PF14235.1 CDI86647.1 - 0.72 9.6 18.6 0.87 9.4 12.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) HCO3_cotransp PF00955.16 CDI86647.1 - 0.75 8.3 5.0 0.79 8.3 3.5 1.0 1 0 0 1 1 1 0 HCO3- transporter family DUF1764 PF08576.5 CDI86647.1 - 0.81 10.4 19.5 1.1 10.0 13.5 1.2 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) DUF3306 PF11748.3 CDI86647.1 - 0.85 10.2 15.4 1.1 9.8 10.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3306) Nucleoside_tran PF01733.13 CDI86647.1 - 0.87 8.6 5.1 0.83 8.7 3.6 1.1 1 0 0 1 1 1 0 Nucleoside transporter SpoVR PF04293.8 CDI86647.1 - 0.87 7.8 15.8 0.95 7.7 11.0 1.0 1 0 0 1 1 1 0 SpoVR like protein Herpes_DNAp_acc PF04929.7 CDI86647.1 - 0.88 8.4 12.1 1 8.2 8.4 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor DUF3292 PF11696.3 CDI86647.1 - 0.89 7.3 6.8 1 7.1 4.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) DUF853 PF05872.7 CDI86647.1 - 0.9 7.8 12.9 1 7.6 8.9 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) Cellulose_synt PF03552.9 CDI86647.1 - 0.91 7.7 8.2 0.98 7.6 5.7 1.0 1 0 0 1 1 1 0 Cellulose synthase Presenilin PF01080.12 CDI86647.1 - 0.98 8.1 8.8 1 8.0 6.1 1.1 1 0 0 1 1 1 0 Presenilin MRP-S26 PF14943.1 CDI86647.1 - 1.1 8.8 18.7 1.4 8.4 13.0 1.2 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 FAM60A PF15396.1 CDI86647.1 - 1.1 8.9 14.0 1.3 8.7 9.7 1.1 1 0 0 1 1 1 0 Protein Family FAM60A DUF4638 PF15472.1 CDI86647.1 - 1.1 8.7 12.8 1.2 8.6 8.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) DUF4512 PF14975.1 CDI86647.1 - 1.1 10.0 8.6 1.6 9.6 5.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4512) Spore_coat_CotO PF14153.1 CDI86647.1 - 1.2 8.5 25.6 1.4 8.3 17.7 1.1 1 0 0 1 1 1 0 Spore coat protein CotO IPK PF03770.11 CDI86647.1 - 1.3 8.5 13.2 37 3.8 9.1 2.0 1 1 0 1 1 1 0 Inositol polyphosphate kinase Pex16 PF08610.5 CDI86647.1 - 1.5 7.7 14.9 1.8 7.4 10.3 1.2 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) FYDLN_acid PF09538.5 CDI86647.1 - 1.5 9.4 9.1 1.9 9.1 6.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) BORG_CEP PF14957.1 CDI86647.1 - 1.5 9.7 11.2 1.8 9.4 7.7 1.1 1 0 0 1 1 1 0 Cdc42 effector F-protein PF00469.15 CDI86647.1 - 1.6 8.0 13.6 1.8 7.8 9.4 1.1 1 0 0 1 1 1 0 Negative factor, (F-Protein) or Nef SAGA-Tad1 PF12767.2 CDI86647.1 - 1.6 8.3 20.3 1.9 8.1 14.0 1.1 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit DUF2058 PF09831.4 CDI86647.1 - 1.6 8.6 29.9 1.9 8.3 20.7 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2058) Glyco_transf_15 PF01793.11 CDI86647.1 - 1.6 7.6 15.8 1.7 7.4 10.9 1.1 1 0 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase Asparaginase_2 PF01112.13 CDI86647.1 - 1.8 7.2 5.0 1.8 7.1 3.5 1.0 1 0 0 1 1 1 0 Asparaginase Dynamin_N PF00350.18 CDI86647.1 - 1.8 8.3 8.3 1.8 8.3 5.8 1.2 1 0 0 1 1 1 0 Dynamin family FAM91_C PF14648.1 CDI86647.1 - 1.8 7.2 8.1 2 7.1 5.6 1.0 1 0 0 1 1 1 0 FAM91 C-terminus CDC45 PF02724.9 CDI86647.1 - 1.8 6.4 17.6 2.3 6.1 12.2 1.0 1 0 0 1 1 1 0 CDC45-like protein Kei1 PF08552.6 CDI86647.1 - 2 8.0 11.4 2.4 7.8 7.9 1.1 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 Miro PF08477.8 CDI86647.1 - 2 8.9 5.5 2.6 8.5 3.8 1.1 1 0 0 1 1 1 0 Miro-like protein Otopetrin PF03189.8 CDI86647.1 - 2.1 7.2 6.9 2.4 7.0 4.8 1.2 1 0 0 1 1 1 0 Otopetrin Peptidase_S15 PF02129.13 CDI86647.1 - 2.2 7.6 13.2 2.3 7.5 9.2 1.1 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) CRF1 PF10380.4 CDI86647.1 - 2.2 8.6 10.6 2.7 8.3 7.4 1.2 1 0 0 1 1 1 0 Transcription factor CRF1 eIF3_subunit PF08597.5 CDI86647.1 - 2.3 7.7 17.6 2.5 7.6 12.2 1.1 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit DUF1266 PF06889.6 CDI86647.1 - 2.3 7.9 13.4 3 7.6 9.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1266) DUF2828 PF11443.3 CDI86647.1 - 2.4 6.2 13.7 2.7 6.0 9.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) DUF3408 PF11888.3 CDI86647.1 - 2.4 8.0 15.2 3.3 7.6 10.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) Maf1 PF09174.5 CDI86647.1 - 2.4 7.9 10.0 3 7.6 6.9 1.1 1 0 0 1 1 1 0 Maf1 regulator Band_3_cyto PF07565.8 CDI86647.1 - 2.5 7.5 17.7 2.8 7.3 12.3 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Gti1_Pac2 PF09729.4 CDI86647.1 - 2.7 7.8 13.2 3.2 7.5 9.2 1.2 1 0 0 1 1 1 0 Gti1/Pac2 family Plasmodium_Vir PF05795.6 CDI86647.1 - 2.8 7.0 7.5 3.2 6.8 5.2 1.0 1 0 0 1 1 1 0 Plasmodium vivax Vir protein DUF3449 PF11931.3 CDI86647.1 - 2.8 7.4 18.1 3.4 7.1 12.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3449) XRN_N PF03159.13 CDI86647.1 - 2.8 7.2 10.5 3 7.1 7.3 1.1 1 0 0 1 1 1 0 XRN 5'-3' exonuclease N-terminus DUF844 PF05815.6 CDI86647.1 - 3 6.5 12.9 3.7 6.3 8.9 1.1 1 0 0 1 1 1 0 Baculovirus protein of unknown function (DUF844) HGTP_anticodon2 PF12745.2 CDI86647.1 - 3.1 6.8 15.2 3.6 6.6 10.5 1.1 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs DUF4220 PF13968.1 CDI86647.1 - 3.2 6.7 9.2 3.6 6.5 6.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4220) SeqA PF03925.8 CDI86647.1 - 3.3 7.3 15.0 4.1 7.0 10.4 1.1 1 0 0 1 1 1 0 SeqA protein UPF0560 PF10577.4 CDI86647.1 - 3.3 5.8 26.8 3.7 5.6 18.6 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 AIF_C PF14721.1 CDI86647.1 - 3.4 7.9 15.8 4.5 7.5 11.0 1.1 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Shisa PF13908.1 CDI86647.1 - 3.6 7.7 17.7 4.4 7.4 12.3 1.2 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Spc7_N PF15402.1 CDI86647.1 - 3.6 5.4 23.4 4.3 5.2 16.2 1.0 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 DUF2422 PF10337.4 CDI86647.1 - 3.8 6.2 10.9 4.7 5.8 7.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2422) CPSF100_C PF13299.1 CDI86647.1 - 3.8 7.6 15.5 4.6 7.4 10.7 1.1 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Asp-B-Hydro_N PF05279.6 CDI86647.1 - 4 7.2 13.4 4.7 6.9 9.3 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region APG6 PF04111.7 CDI86647.1 - 4 6.3 21.7 4.6 6.2 15.0 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 Conotoxin PF02950.12 CDI86647.1 - 4.4 8.1 17.6 5.3 7.9 5.0 2.1 1 1 1 2 2 2 0 Conotoxin DUF2126 PF09899.4 CDI86647.1 - 4.4 5.2 13.0 4.8 5.0 9.0 1.0 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) DUF702 PF05142.7 CDI86647.1 - 4.7 7.3 17.7 5.5 7.1 12.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF702) Ndc1_Nup PF09531.5 CDI86647.1 - 4.8 5.4 17.0 5 5.4 11.8 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup BTV_NS2 PF04514.7 CDI86647.1 - 4.9 5.9 13.6 5.9 5.6 9.4 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 RP-C_C PF11800.3 CDI86647.1 - 5 6.7 16.3 5.6 6.6 11.3 1.0 1 0 0 1 1 1 0 Replication protein C C-terminal region CobT PF06213.7 CDI86647.1 - 5.3 6.1 15.5 6.2 5.8 10.7 1.0 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Sec62 PF03839.11 CDI86647.1 - 5.3 6.3 11.8 6.1 6.1 8.1 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 Paramyxo_ncap PF00973.14 CDI86647.1 - 5.5 5.5 13.5 5.9 5.4 9.3 1.0 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein DHHW PF14286.1 CDI86647.1 - 5.8 6.1 14.6 6.7 5.9 10.1 1.1 1 0 0 1 1 1 0 DHHW protein Endonuc_Holl PF10107.4 CDI86647.1 - 5.9 6.5 17.6 7.4 6.2 12.2 1.1 1 0 0 1 1 1 0 Endonuclease related to archaeal Holliday junction resolvase DUF4652 PF15525.1 CDI86647.1 - 6.1 6.2 12.3 9 5.6 8.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4652) PBP1_TM PF14812.1 CDI86647.1 - 6.5 7.1 11.4 11 6.4 7.9 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF3381 PF11861.3 CDI86647.1 - 8.3 5.8 18.3 11 5.5 12.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) DUF3373 PF11853.3 CDI86647.1 - 8.4 4.7 13.9 9.4 4.6 9.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) Glyco_transf_6 PF03414.8 CDI86647.1 - 9 4.6 11.0 10 4.4 7.6 1.1 1 0 0 1 1 1 0 Glycosyltransferase family 6 CMS1 PF14617.1 CDI86647.1 - 9.5 5.2 10.3 12 4.8 7.1 1.1 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit Suf PF05843.9 CDI86648.1 - 0.0049 16.6 9.7 0.0049 16.6 6.7 1.0 1 0 0 1 1 1 1 Suppressor of forked protein (Suf) ATP-grasp PF02222.17 CDI86648.1 - 0.012 14.9 0.8 0.013 14.8 0.5 1.1 1 0 0 1 1 1 0 ATP-grasp domain FimP PF09766.4 CDI86648.1 - 0.018 14.1 10.8 0.018 14.1 7.5 1.0 1 0 0 1 1 1 0 Fms-interacting protein Nucleos_tra2_C PF07662.8 CDI86648.1 - 0.023 14.1 0.2 0.027 13.9 0.1 1.2 1 0 0 1 1 1 0 Na+ dependent nucleoside transporter C-terminus dsDNA_bind PF01984.15 CDI86648.1 - 0.03 14.3 16.6 0.036 14.0 11.5 1.2 1 0 0 1 1 1 0 Double-stranded DNA-binding domain Peptidase_S49_N PF08496.5 CDI86648.1 - 0.053 13.3 0.7 0.052 13.3 0.5 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Pex14_N PF04695.8 CDI86648.1 - 0.056 13.4 7.0 0.056 13.4 4.9 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region MAT1 PF06391.8 CDI86648.1 - 0.057 12.9 6.3 0.062 12.8 4.4 1.0 1 0 0 1 1 1 0 CDK-activating kinase assembly factor MAT1 BTB PF00651.26 CDI86648.1 - 0.06 13.3 0.1 0.079 12.9 0.1 1.4 1 1 0 1 1 1 0 BTB/POZ domain LIM_bind PF01803.11 CDI86648.1 - 0.065 12.3 7.2 0.072 12.1 5.0 1.0 1 0 0 1 1 1 0 LIM-domain binding protein BRF1 PF07741.8 CDI86648.1 - 0.078 13.2 2.5 0.081 13.1 1.7 1.1 1 0 0 1 1 1 0 Brf1-like TBP-binding domain Spt20 PF12090.3 CDI86648.1 - 0.099 11.9 7.2 0.11 11.8 5.0 1.2 1 0 0 1 1 1 0 Spt20 family Afi1 PF07792.7 CDI86648.1 - 0.12 12.3 4.0 0.11 12.4 2.8 1.1 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking DUF4557 PF15101.1 CDI86648.1 - 0.13 12.0 9.6 0.12 12.1 6.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) DENN PF02141.16 CDI86648.1 - 0.14 11.8 1.8 0.16 11.6 1.3 1.1 1 0 0 1 1 1 0 DENN (AEX-3) domain PIG-P PF08510.7 CDI86648.1 - 0.18 11.4 0.7 0.2 11.2 0.5 1.1 1 0 0 1 1 1 0 PIG-P DUF4199 PF13858.1 CDI86648.1 - 0.21 11.5 4.4 0.25 11.2 3.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) Pex16 PF08610.5 CDI86648.1 - 0.21 10.5 4.0 0.22 10.4 2.8 1.1 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) RED_N PF07808.8 CDI86648.1 - 0.22 10.6 8.8 0.23 10.6 6.1 1.1 1 0 0 1 1 1 0 RED-like protein N-terminal region DUF912 PF06024.7 CDI86648.1 - 0.27 11.2 2.0 0.3 11.1 1.4 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF3371 PF11851.3 CDI86648.1 - 0.31 11.7 11.5 0.33 11.6 8.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3371) DUF4175 PF13779.1 CDI86648.1 - 0.35 8.5 19.8 0.34 8.5 13.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) PAT1 PF09770.4 CDI86648.1 - 0.52 8.4 17.9 0.52 8.4 12.4 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF2722 PF10846.3 CDI86648.1 - 0.52 9.2 10.1 0.59 9.1 7.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Conotoxin PF02950.12 CDI86648.1 - 0.54 11.0 2.9 0.67 10.7 2.0 1.2 1 0 0 1 1 1 0 Conotoxin Med15 PF09606.5 CDI86648.1 - 0.58 8.3 26.1 0.58 8.2 18.1 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Serinc PF03348.10 CDI86648.1 - 0.66 8.6 3.1 0.64 8.6 2.2 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) OmpH PF03938.9 CDI86648.1 - 0.68 9.8 20.9 0.74 9.7 14.5 1.0 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) CRF1 PF10380.4 CDI86648.1 - 0.74 10.1 4.1 0.83 9.9 2.8 1.1 1 0 0 1 1 1 0 Transcription factor CRF1 DUF775 PF05603.7 CDI86648.1 - 0.75 9.2 7.2 0.82 9.1 5.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF775) CagX PF03524.10 CDI86648.1 - 0.82 8.8 4.5 0.87 8.8 3.1 1.1 1 0 0 1 1 1 0 Conjugal transfer protein WASH-7_C PF14746.1 CDI86648.1 - 0.91 9.1 5.6 1 8.9 3.9 1.1 1 0 0 1 1 1 0 WASH complex subunit 7, C-terminal RAB3GAP2_N PF14655.1 CDI86648.1 - 1.1 8.1 6.4 1.4 7.8 4.5 1.3 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus FCP1_C PF09309.5 CDI86648.1 - 1.8 7.7 7.7 2 7.6 5.3 1.1 1 0 0 1 1 1 0 FCP1, C-terminal Gag_spuma PF03276.9 CDI86648.1 - 2.2 6.4 12.9 2.2 6.5 9.0 1.0 1 0 0 1 1 1 0 Spumavirus gag protein DivIC PF04977.10 CDI86648.1 - 4.7 6.7 15.1 6.1 6.3 10.5 1.2 1 0 0 1 1 1 0 Septum formation initiator DUF4407 PF14362.1 CDI86648.1 - 7 5.5 8.8 7.2 5.4 6.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) SHR3_chaperone PF08229.6 CDI86648.1 - 8.9 5.2 8.7 10 4.9 6.0 1.1 1 0 0 1 1 1 0 ER membrane protein SH3 AMP-binding PF00501.23 CDI86649.1 - 0.77 8.0 6.3 0.82 7.9 4.3 1.0 1 0 0 1 1 1 0 AMP-binding enzyme SMC_hinge PF06470.8 CDI86649.1 - 2.6 8.0 9.9 3.5 7.6 6.9 1.5 1 1 0 1 1 1 0 SMC proteins Flexible Hinge Domain PPP4R2 PF09184.6 CDI86649.1 - 6.9 6.1 26.2 7.7 5.9 18.2 1.1 1 0 0 1 1 1 0 PPP4R2 IncA PF04156.9 CDI86650.1 - 0.0028 17.2 9.1 0.005 16.4 6.3 1.4 1 0 0 1 1 1 1 IncA protein DUF4131 PF13567.1 CDI86650.1 - 0.0096 15.3 1.0 0.012 15.0 0.7 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4131) CD20 PF04103.10 CDI86650.1 - 0.014 15.2 0.9 0.014 15.2 0.6 1.6 1 1 0 1 1 1 0 CD20-like family CMV_1a PF12467.3 CDI86650.1 - 0.027 14.8 1.5 0.032 14.5 1.1 1.1 1 0 0 1 1 1 0 Cucumber mosaic virus 1a protein family Glyco_hydro_20b PF02838.10 CDI86650.1 - 0.087 13.3 3.4 0.11 12.9 2.4 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 20, domain 2 PrpF PF04303.8 CDI86650.1 - 0.11 11.1 1.9 0.14 10.9 1.3 1.1 1 0 0 1 1 1 0 PrpF protein RAB3GAP2_N PF14655.1 CDI86650.1 - 0.12 11.3 4.5 0.14 11.1 3.1 1.2 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus FAD-SLDH PF12318.3 CDI86650.1 - 0.15 11.6 12.1 0.19 11.4 8.4 1.1 1 0 0 1 1 1 0 Membrane bound FAD containing D-sorbitol dehydrogenase DUF2232 PF09991.4 CDI86650.1 - 0.3 10.0 4.2 0.37 9.7 2.9 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) DUF2939 PF11159.3 CDI86650.1 - 0.35 11.0 12.9 0.51 10.5 9.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2939) Serinc PF03348.10 CDI86650.1 - 0.4 9.3 4.6 0.41 9.3 3.2 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) DUF3138 PF11336.3 CDI86650.1 - 0.86 7.7 10.5 1 7.4 7.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) R_equi_Vir PF05526.6 CDI86650.1 - 0.87 9.2 6.5 1.1 8.8 4.5 1.1 1 0 0 1 1 1 0 Rhodococcus equi virulence-associated protein DUF2422 PF10337.4 CDI86650.1 - 1.7 7.3 10.1 2 7.1 7.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2422) PAT1 PF09770.4 CDI86650.1 - 3.2 5.8 21.0 3.2 5.8 14.6 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 RskA PF10099.4 CDI86650.1 - 4.1 7.1 21.3 35 4.0 14.8 1.9 1 1 0 1 1 1 0 Anti-sigma-K factor rskA LPP20 PF02169.11 CDI86650.1 - 4.4 7.4 9.4 5.6 7.1 6.5 1.2 1 0 0 1 1 1 0 LPP20 lipoprotein DUF4367 PF14285.1 CDI86650.1 - 5 6.4 5.0 9.3 5.5 3.4 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4367) DivIC PF04977.10 CDI86650.1 - 5.6 6.5 10.2 8.4 5.9 7.1 1.3 1 0 0 1 1 1 0 Septum formation initiator TFIIA PF03153.8 CDI86650.1 - 6 6.6 16.7 6.5 6.5 11.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF3373 PF11853.3 CDI86650.1 - 7.9 4.8 8.7 9.4 4.6 6.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) DUF3450 PF11932.3 CDI86650.1 - 9.1 5.4 22.9 19 4.4 15.6 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) WW PF00397.21 CDI86651.1 - 8.2e-16 57.5 9.8 6.6e-10 38.6 1.8 2.9 2 0 0 2 2 2 2 WW domain FF PF01846.14 CDI86651.1 - 9.4e-11 41.4 0.0 9.4e-11 41.4 0.0 3.5 3 0 0 3 3 3 1 FF domain DUF4647 PF15504.1 CDI86652.1 - 10 4.8 46.6 12 4.5 32.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4647) FA_desaturase PF00487.19 CDI86653.1 - 0.073 12.5 8.0 0.51 9.7 0.0 2.3 2 0 0 2 2 2 0 Fatty acid desaturase OPT PF03169.10 CDI86653.1 - 0.15 10.5 0.9 12 4.1 0.5 2.9 1 1 0 2 2 2 0 OPT oligopeptide transporter protein Polysacc_synt_3 PF13440.1 CDI86655.1 - 0.00037 20.0 12.7 0.00039 19.9 8.8 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Tetraspannin PF00335.15 CDI86655.1 - 0.026 13.7 0.5 0.092 12.0 0.3 1.8 1 1 0 1 1 1 0 Tetraspanin family Med15 PF09606.5 CDI86655.1 - 0.046 11.9 59.7 0.058 11.5 41.4 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Raftlin PF15250.1 CDI86655.1 - 0.064 11.7 15.8 0.081 11.4 11.0 1.1 1 0 0 1 1 1 0 Raftlin Zip PF02535.17 CDI86655.1 - 0.092 11.7 24.0 0.14 11.1 16.6 1.6 1 1 0 1 1 1 0 ZIP Zinc transporter GAGA_bind PF06217.7 CDI86655.1 - 0.13 12.1 18.3 0.15 12.0 12.7 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family PCEMA1 PF07418.6 CDI86655.1 - 0.22 10.8 7.2 0.29 10.4 5.0 1.2 1 0 0 1 1 1 0 Acidic phosphoprotein precursor PCEMA1 TraX PF05857.6 CDI86655.1 - 0.28 10.7 4.0 0.37 10.3 2.8 1.2 1 0 0 1 1 1 0 TraX protein CD20 PF04103.10 CDI86655.1 - 0.32 10.9 16.3 79 3.1 11.3 2.5 1 1 0 1 1 1 0 CD20-like family FAM60A PF15396.1 CDI86655.1 - 0.61 9.7 17.6 0.99 9.1 12.2 1.3 1 0 0 1 1 1 0 Protein Family FAM60A Tau95 PF09734.4 CDI86655.1 - 0.76 9.0 12.0 0.99 8.6 8.3 1.1 1 0 0 1 1 1 0 RNA polymerase III transcription factor (TF)IIIC subunit DUF1183 PF06682.7 CDI86655.1 - 1.9 8.0 12.7 0.24 10.9 6.2 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1183) AAA_23 PF13476.1 CDI86655.1 - 2.1 8.6 14.7 3 8.1 10.2 1.3 1 0 0 1 1 1 0 AAA domain EIF4E-T PF10477.4 CDI86655.1 - 2.1 7.0 19.5 2.2 6.9 13.5 1.1 1 0 0 1 1 1 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E DUF1510 PF07423.6 CDI86655.1 - 3.7 6.8 22.9 2.3 7.5 14.6 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) PAT1 PF09770.4 CDI86655.1 - 7.3 4.6 52.5 9.6 4.2 36.4 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Secretin_N_2 PF07655.8 CDI86656.1 - 0.023 15.0 24.7 0.32 11.3 8.2 2.2 2 0 0 2 2 2 0 Secretin N-terminal domain NAM-associated PF14303.1 CDI86656.1 - 0.053 13.8 1.9 0.14 12.4 0.1 2.0 2 0 0 2 2 2 0 No apical meristem-associated C-terminal domain POX PF07526.6 CDI86656.1 - 0.062 13.5 6.1 0.32 11.2 1.5 2.2 2 0 0 2 2 2 0 Associated with HOX CDK2AP PF09806.4 CDI86656.1 - 0.087 13.0 12.0 0.98 9.6 3.5 2.2 2 0 0 2 2 2 0 Cyclin-dependent kinase 2-associated protein Dus PF01207.12 CDI86656.1 - 0.18 10.6 0.0 0.37 9.5 0.0 1.6 1 1 1 2 2 2 0 Dihydrouridine synthase (Dus) Herpes_capsid PF06112.6 CDI86656.1 - 0.35 10.8 19.1 1.1 9.2 4.7 2.2 2 0 0 2 2 2 0 Gammaherpesvirus capsid protein Chorion_2 PF03964.10 CDI86656.1 - 0.94 10.0 13.7 2.9 8.4 1.5 2.2 2 0 0 2 2 2 0 Chorion family 2 Pox_E2-like PF04497.7 CDI86656.1 - 0.95 7.4 3.5 0.94 7.4 0.1 1.9 2 0 0 2 2 2 0 Poxviridae protein TraG-D_C PF12696.2 CDI86656.1 - 2.3 8.0 10.9 1.2 9.0 1.3 2.2 2 0 0 2 2 2 0 TraM recognition site of TraD and TraG DUF1117 PF06547.7 CDI86656.1 - 3 7.9 20.6 2.5 8.2 5.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1117) Macoilin PF09726.4 CDI86656.1 - 4.1 5.5 15.9 0.59 8.3 3.5 2.0 2 0 0 2 2 2 0 Transmembrane protein APC_CDC26 PF10471.4 CDI86656.1 - 4.7 8.0 7.1 10 6.9 1.0 2.4 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit 1 DUF515 PF04415.7 CDI86656.1 - 5 5.2 18.5 1.8 6.7 2.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF515) Period_C PF12114.3 CDI86656.1 - 6.1 6.3 24.7 5.8 6.4 3.8 2.1 2 0 0 2 2 2 0 Period protein 2/3C-terminal region Autophagy_N PF03986.8 CDI86657.1 - 6.8 6.4 19.9 7.3 6.3 13.8 1.0 1 0 0 1 1 1 0 Autophagocytosis associated protein (Atg3), N-terminal domain HapK PF11639.3 CDI86658.1 - 0.017 15.7 0.1 0.047 14.3 0.0 1.7 2 0 0 2 2 2 0 REDY-like protein HapK TPR_14 PF13428.1 CDI86659.1 - 0.016 15.8 0.3 0.036 14.6 0.2 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat Apc3 PF12895.2 CDI86659.1 - 0.047 13.8 0.1 0.09 12.9 0.1 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 CDI86659.1 - 0.052 14.2 0.3 0.052 14.2 0.2 1.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.12 CDI86659.1 - 0.058 13.3 0.1 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat PH_6 PF15406.1 CDI86659.1 - 0.12 12.4 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 Pleckstrin homology domain TPR_6 PF13174.1 CDI86659.1 - 0.13 12.7 0.1 0.27 11.7 0.1 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF4597 PF15366.1 CDI86660.1 - 0.014 14.9 3.5 0.02 14.4 0.3 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4597) Rtf2 PF04641.7 CDI86661.1 - 1.6 7.9 11.8 1.8 7.6 8.1 1.2 1 0 0 1 1 1 0 Rtf2 RING-finger MSA_2 PF00985.12 CDI86661.1 - 3.5 7.7 7.3 4.1 7.4 5.1 1.2 1 0 0 1 1 1 0 Merozoite Surface Antigen 2 (MSA-2) family PGA2 PF07543.7 CDI86663.1 - 0.73 9.6 6.8 1.6 8.5 4.7 1.5 1 0 0 1 1 1 0 Protein trafficking PGA2 DUF4367 PF14285.1 CDI86663.1 - 2.1 7.6 4.9 14 4.9 1.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4367) Mito_carr PF00153.22 CDI86663.1 - 2.5 7.8 7.3 0.81 9.4 0.9 2.5 2 0 0 2 2 2 0 Mitochondrial carrier protein PAT1 PF09770.4 CDI86663.1 - 8.9 4.4 23.9 9.6 4.2 16.5 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 RAB3GAP2_N PF14655.1 CDI86663.1 - 9.1 5.1 8.6 29 3.5 6.0 1.6 1 1 1 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Med15 PF09606.5 CDI86664.1 - 0.009 14.2 52.3 0.0095 14.2 36.3 1.1 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal PAT1 PF09770.4 CDI86664.1 - 0.012 13.9 37.6 0.012 13.8 26.1 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 RskA PF10099.4 CDI86664.1 - 0.031 14.0 21.1 0.021 14.5 5.2 2.1 1 1 1 2 2 2 0 Anti-sigma-K factor rskA BBP1_N PF15271.1 CDI86664.1 - 0.053 13.8 9.2 0.069 13.5 6.4 1.1 1 0 0 1 1 1 0 Spindle pole body component BBP1, Mps2-binding protein MRP-S31 PF15433.1 CDI86664.1 - 0.11 11.8 17.5 0.15 11.4 12.1 1.1 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 CDC45 PF02724.9 CDI86664.1 - 0.12 10.3 12.2 0.14 10.1 8.4 1.1 1 0 0 1 1 1 0 CDC45-like protein Spore_coat_CotO PF14153.1 CDI86664.1 - 0.17 11.2 26.5 0.2 11.0 18.4 1.1 1 0 0 1 1 1 0 Spore coat protein CotO APG6 PF04111.7 CDI86664.1 - 0.18 10.7 22.0 0.21 10.6 15.2 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF853 PF05872.7 CDI86664.1 - 0.2 9.9 11.4 0.23 9.7 7.9 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) DUF4045 PF13254.1 CDI86664.1 - 0.21 10.8 13.0 0.23 10.6 9.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) GAGA_bind PF06217.7 CDI86664.1 - 0.4 10.5 14.2 0.46 10.3 9.8 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family Peptidase_S15 PF02129.13 CDI86664.1 - 0.48 9.8 9.0 0.67 9.3 6.2 1.3 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) SID-1_RNA_chan PF13965.1 CDI86664.1 - 0.52 8.4 6.8 0.62 8.1 4.7 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 eIF-3_zeta PF05091.7 CDI86664.1 - 0.54 8.8 16.1 0.73 8.3 11.2 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) CRT10 PF08728.5 CDI86664.1 - 0.62 7.9 6.3 0.65 7.9 4.4 1.0 1 0 0 1 1 1 0 CRT10 FLO_LFY PF01698.11 CDI86664.1 - 0.76 8.5 14.1 0.91 8.3 9.8 1.2 1 0 0 1 1 1 0 Floricaula / Leafy protein FHIPEP PF00771.15 CDI86664.1 - 0.83 7.9 13.9 0.56 8.4 8.2 1.5 1 1 0 1 1 1 0 FHIPEP family Ycf1 PF05758.7 CDI86664.1 - 0.84 7.2 16.7 0.96 7.0 11.6 1.0 1 0 0 1 1 1 0 Ycf1 DDRGK PF09756.4 CDI86664.1 - 1.2 8.5 25.0 1.6 8.0 17.4 1.3 1 0 0 1 1 1 0 DDRGK domain FAM60A PF15396.1 CDI86664.1 - 1.2 8.8 12.6 1.6 8.4 8.8 1.2 1 0 0 1 1 1 0 Protein Family FAM60A SET PF00856.23 CDI86664.1 - 1.4 9.1 3.5 1.9 8.7 2.4 1.2 1 0 0 1 1 1 0 SET domain Hid1 PF12722.2 CDI86664.1 - 1.5 6.4 16.8 1.7 6.2 11.7 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein TFIIA PF03153.8 CDI86664.1 - 1.5 8.6 32.0 1.8 8.3 22.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit AUX_IAA PF02309.11 CDI86664.1 - 1.6 8.4 11.3 1.9 8.1 7.8 1.1 1 0 0 1 1 1 0 AUX/IAA family PA26 PF04636.8 CDI86664.1 - 1.7 7.2 9.4 1.8 7.1 6.5 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) PLRV_ORF5 PF01690.12 CDI86664.1 - 1.8 7.6 14.3 2.1 7.4 9.9 1.0 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Mem_trans PF03547.13 CDI86664.1 - 2 6.6 4.8 2.2 6.4 3.3 1.1 1 0 0 1 1 1 0 Membrane transport protein FliP PF00813.15 CDI86664.1 - 2.3 7.8 6.3 2.6 7.7 4.4 1.2 1 0 0 1 1 1 0 FliP family DUF2201_N PF13203.1 CDI86664.1 - 2.6 7.1 19.0 2.9 6.9 13.2 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain Pex16 PF08610.5 CDI86664.1 - 3 6.7 12.7 3.7 6.4 8.8 1.2 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) Presenilin PF01080.12 CDI86664.1 - 3.1 6.5 8.2 3.8 6.2 5.7 1.3 1 0 0 1 1 1 0 Presenilin DHHW PF14286.1 CDI86664.1 - 3.1 7.0 10.8 3.4 6.9 7.5 1.1 1 0 0 1 1 1 0 DHHW protein Ribosomal_60s PF00428.14 CDI86664.1 - 3.6 8.0 10.1 12 6.3 0.3 2.3 2 0 0 2 2 2 0 60s Acidic ribosomal protein Band_3_cyto PF07565.8 CDI86664.1 - 4.1 6.8 14.9 6.7 6.1 10.3 1.4 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Hist_deacetyl PF00850.14 CDI86664.1 - 4.1 6.6 9.0 6.5 5.9 6.2 1.3 1 0 0 1 1 1 0 Histone deacetylase domain DUF3260 PF11658.3 CDI86664.1 - 5.1 5.1 12.5 6 4.8 8.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3260) DUF4175 PF13779.1 CDI86664.1 - 5.8 4.4 51.0 7.2 4.1 35.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) PsaN PF05479.6 CDI86664.1 - 6.2 6.8 7.7 3 7.8 0.3 2.3 2 1 0 2 2 2 0 Photosystem I reaction centre subunit N (PSAN or PSI-N) TCP PF03634.8 CDI86664.1 - 8.9 6.6 20.9 14 6.0 14.5 1.4 1 1 0 1 1 1 0 TCP family transcription factor Neur_chan_memb PF02932.11 CDI86664.1 - 9.1 6.0 11.7 11 5.7 8.1 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Asp-B-Hydro_N PF05279.6 CDI86664.1 - 9.7 5.9 15.8 11 5.7 10.9 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region YjgP_YjgQ PF03739.9 CDI86664.1 - 9.8 4.7 8.2 11 4.6 5.7 1.2 1 0 0 1 1 1 0 Predicted permease YjgP/YjgQ family MLANA PF14991.1 CDI86665.1 - 0.05 13.6 0.0 0.089 12.8 0.0 1.4 1 0 0 1 1 1 0 Protein melan-A SR-25 PF10500.4 CDI86666.1 - 0.00056 19.4 22.8 0.00068 19.1 15.8 1.0 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Cwf_Cwc_15 PF04889.7 CDI86666.1 - 0.14 11.8 16.8 0.18 11.5 11.7 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF572 PF04502.8 CDI86666.1 - 0.26 10.4 19.9 0.32 10.1 13.8 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Shadoo PF14999.1 CDI86666.1 - 0.3 10.9 6.2 0.43 10.4 4.3 1.3 1 0 0 1 1 1 0 Shadow of prion protein, neuroprotective CAF-1_p150 PF11600.3 CDI86666.1 - 0.51 9.6 24.9 0.67 9.2 17.3 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Neur_chan_memb PF02932.11 CDI86666.1 - 0.57 10.0 14.0 0.6 9.9 9.7 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Dicty_REP PF05086.7 CDI86666.1 - 0.58 7.8 22.9 0.65 7.6 15.9 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein YL1 PF05764.8 CDI86666.1 - 0.59 9.6 21.2 0.7 9.4 14.7 1.1 1 0 0 1 1 1 0 YL1 nuclear protein Nop53 PF07767.6 CDI86666.1 - 0.59 9.0 20.6 0.74 8.7 14.3 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Zip PF02535.17 CDI86666.1 - 0.74 8.7 6.6 0.9 8.4 4.6 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter DUF3827 PF12877.2 CDI86666.1 - 0.77 7.7 20.1 0.91 7.5 13.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) Suf PF05843.9 CDI86666.1 - 0.81 9.3 27.7 1 9.0 19.2 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF605 PF04652.11 CDI86666.1 - 0.88 8.8 29.7 1.1 8.6 20.6 1.0 1 0 0 1 1 1 0 Vta1 like CDC45 PF02724.9 CDI86666.1 - 1.4 6.8 21.7 1.6 6.6 15.1 1.0 1 0 0 1 1 1 0 CDC45-like protein Utp14 PF04615.8 CDI86666.1 - 1.5 6.9 27.1 1.7 6.6 18.8 1.0 1 0 0 1 1 1 0 Utp14 protein DUF1675 PF07897.6 CDI86666.1 - 1.5 8.6 25.0 1.8 8.3 17.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) SAGA-Tad1 PF12767.2 CDI86666.1 - 1.5 8.3 21.4 1.7 8.2 14.9 1.1 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit XAP5 PF04921.9 CDI86666.1 - 1.6 8.2 15.7 1.9 8.0 10.9 1.1 1 0 0 1 1 1 0 XAP5, circadian clock regulator FAM60A PF15396.1 CDI86666.1 - 1.6 8.4 19.4 2 8.1 13.4 1.1 1 0 0 1 1 1 0 Protein Family FAM60A Med15 PF09606.5 CDI86666.1 - 1.6 6.7 48.1 2 6.4 33.3 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF3801 PF12687.2 CDI86666.1 - 1.8 8.0 17.7 2.4 7.7 12.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3801) DUF913 PF06025.7 CDI86666.1 - 3.1 6.4 13.4 3.3 6.3 9.3 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) FLO_LFY PF01698.11 CDI86666.1 - 3.4 6.4 20.9 3.9 6.2 14.5 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein Macoilin PF09726.4 CDI86666.1 - 3.6 5.7 22.9 4.7 5.3 15.9 1.2 1 0 0 1 1 1 0 Transmembrane protein Menin PF05053.8 CDI86666.1 - 4 5.4 15.4 4.5 5.3 10.7 1.1 1 0 0 1 1 1 0 Menin Clathrin_lg_ch PF01086.12 CDI86666.1 - 4 7.2 22.2 4.9 6.9 15.4 1.0 1 0 0 1 1 1 0 Clathrin light chain DNA_pol_viral_N PF00242.12 CDI86666.1 - 4.2 6.2 27.2 4.8 6.0 18.9 1.0 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain AUX_IAA PF02309.11 CDI86666.1 - 4.5 6.9 19.3 5.8 6.5 13.4 1.2 1 0 0 1 1 1 0 AUX/IAA family RR_TM4-6 PF06459.7 CDI86666.1 - 4.6 7.0 17.8 5.6 6.7 12.3 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 PAT1 PF09770.4 CDI86666.1 - 4.6 5.3 35.7 5.5 5.0 24.7 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF2868 PF11067.3 CDI86666.1 - 5.4 6.0 18.5 5.9 5.9 12.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2868) DUF3337 PF11816.3 CDI86666.1 - 6.4 6.0 18.0 7.8 5.7 12.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3337) DUF4551 PF15087.1 CDI86666.1 - 9.2 4.4 19.3 10 4.3 13.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) DUF2754 PF10953.3 CDI86667.1 - 0.044 13.8 0.2 0.044 13.8 0.2 1.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2754) Peptidase_M20 PF01546.23 CDI86668.1 - 1.4e-31 109.5 0.3 2e-31 108.9 0.2 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 CDI86668.1 - 7e-10 38.6 0.0 1.9e-09 37.2 0.0 1.7 1 0 0 1 1 1 1 Peptidase dimerisation domain Ribosomal_L16 PF00252.13 CDI86670.1 - 4.4e-28 97.6 0.0 1.4e-27 96.0 0.0 1.7 1 1 0 1 1 1 1 Ribosomal protein L16p/L10e BCAS2 PF05700.6 CDI86671.1 - 1.8e-38 132.2 3.0 2.5e-38 131.7 2.1 1.1 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) eRF1_1 PF03463.10 CDI86671.1 - 0.028 14.0 0.1 0.041 13.4 0.1 1.3 1 0 0 1 1 1 0 eRF1 domain 1 Metal_resist PF13801.1 CDI86671.1 - 0.032 14.2 0.2 0.032 14.2 0.2 1.9 2 0 0 2 2 2 0 Heavy-metal resistance DUF2361 PF10153.4 CDI86671.1 - 0.1 12.8 1.0 0.2 11.8 0.7 1.6 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2361) TMPIT PF07851.8 CDI86671.1 - 0.12 11.4 1.7 0.17 10.9 1.2 1.2 1 0 0 1 1 1 0 TMPIT-like protein TMF_TATA_bd PF12325.3 CDI86671.1 - 1.4 8.7 10.0 0.042 13.5 2.6 1.6 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF1843 PF08898.5 CDI86671.1 - 4.8 7.2 8.5 0.23 11.5 0.6 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1843) PIG-L PF02585.12 CDI86673.1 - 6.9e-19 68.6 0.0 2.3e-18 66.9 0.0 1.9 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase TRAP_alpha PF03896.11 CDI86673.1 - 0.077 11.9 3.5 1.6 7.6 0.3 2.5 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit Ycf1 PF05758.7 CDI86673.1 - 4.6 4.8 9.4 1.1 6.8 1.9 2.0 2 0 0 2 2 2 0 Ycf1 CS PF04969.11 CDI86674.1 - 3.7e-11 43.4 0.0 7.6e-11 42.4 0.0 1.6 1 0 0 1 1 1 1 CS domain CDC37_N PF03234.9 CDI86674.1 - 0.014 15.7 1.8 0.014 15.7 1.2 3.8 4 0 0 4 4 4 0 Cdc37 N terminal kinase binding Hex_IIIa PF02455.11 CDI86674.1 - 6.1 5.4 13.1 0.52 8.9 1.3 2.3 2 0 0 2 2 2 0 Hexon-associated protein (IIIa) COX2 PF00116.15 CDI86675.1 - 9.1e-38 128.7 0.0 1.2e-37 128.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome C oxidase subunit II, periplasmic domain Med15 PF09606.5 CDI86677.1 - 0.0045 15.2 29.2 0.0045 15.2 20.2 2.7 2 1 0 2 2 2 1 ARC105 or Med15 subunit of Mediator complex non-fungal DUF3377 PF11857.3 CDI86677.1 - 0.049 13.2 0.1 0.049 13.2 0.1 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF3377) FAM176 PF14851.1 CDI86677.1 - 0.53 9.9 25.2 1.4 8.6 3.9 3.1 1 1 1 3 3 3 0 FAM176 family FAM60A PF15396.1 CDI86677.1 - 0.54 9.9 23.2 0.63 9.7 2.3 2.2 2 0 0 2 2 2 0 Protein Family FAM60A DUF1510 PF07423.6 CDI86677.1 - 4.2 6.6 29.6 2.4 7.4 4.9 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1510) SOBP PF15279.1 CDI86677.1 - 6.2 7.1 34.1 1.5 9.1 8.6 2.1 2 0 0 2 2 2 0 Sine oculis-binding protein APC_CDC26 PF10471.4 CDI86677.1 - 7.7 7.3 68.8 0.71 10.6 7.5 3.7 3 1 0 3 3 3 0 Anaphase-promoting complex APC subunit 1 FHIPEP PF00771.15 CDI86677.1 - 9.2 4.4 32.2 0.073 11.3 6.3 2.8 2 1 1 3 3 3 0 FHIPEP family Dapper PF15268.1 CDI86677.1 - 9.5 4.8 42.5 12 4.5 29.4 1.1 1 0 0 1 1 1 0 Dapper Activator_LAG-3 PF11498.3 CDI86678.1 - 0.00073 18.4 65.1 0.0013 17.6 9.9 2.5 2 0 0 2 2 2 2 Transcriptional activator LAG-3 DUF2052 PF09747.4 CDI86678.1 - 0.0064 16.4 28.1 0.045 13.6 9.9 2.3 2 0 0 2 2 2 2 Coiled-coil domain containing protein (DUF2052) RNA_pol_Rpb1_5 PF04998.12 CDI86678.1 - 0.014 14.6 2.7 0.024 13.9 1.9 1.3 1 1 0 1 1 1 0 RNA polymerase Rpb1, domain 5 FimP PF09766.4 CDI86678.1 - 0.017 14.2 35.0 0.077 12.0 11.6 2.3 2 0 0 2 2 2 0 Fms-interacting protein Peptidase_S49_N PF08496.5 CDI86678.1 - 0.055 13.2 16.0 0.33 10.7 6.1 2.3 2 0 0 2 2 2 0 Peptidase family S49 N-terminal SAGA-Tad1 PF12767.2 CDI86678.1 - 0.069 12.8 20.8 0.44 10.1 7.3 2.3 2 0 0 2 2 2 0 Transcriptional regulator of RNA polII, SAGA, subunit Raftlin PF15250.1 CDI86678.1 - 0.21 10.0 20.9 0.22 9.9 8.0 2.1 2 0 0 2 2 2 0 Raftlin Potyvirid-P3 PF13608.1 CDI86678.1 - 0.29 10.2 16.5 0.017 14.3 4.9 2.1 2 0 0 2 2 2 0 Protein P3 of Potyviral polyprotein GAGA_bind PF06217.7 CDI86678.1 - 0.31 10.9 19.9 1.3 8.8 7.3 2.2 2 0 0 2 2 2 0 GAGA binding protein-like family FAM176 PF14851.1 CDI86678.1 - 0.37 10.4 17.1 0.11 12.1 3.6 2.3 2 0 0 2 2 2 0 FAM176 family CD20 PF04103.10 CDI86678.1 - 0.42 10.5 5.7 3.5 7.5 1.6 2.8 2 0 0 2 2 2 0 CD20-like family Serinc PF03348.10 CDI86678.1 - 0.43 9.2 22.8 0.51 9.0 8.4 2.2 2 0 0 2 2 2 0 Serine incorporator (Serinc) Macoilin PF09726.4 CDI86678.1 - 0.48 8.6 30.1 0.63 8.2 20.9 1.1 1 0 0 1 1 1 0 Transmembrane protein EPL1 PF10513.4 CDI86678.1 - 0.57 10.4 18.1 2 8.6 1.4 2.4 2 0 0 2 2 2 0 Enhancer of polycomb-like Folate_carrier PF01770.13 CDI86678.1 - 0.85 8.0 15.9 0.51 8.7 4.5 2.2 2 0 0 2 2 2 0 Reduced folate carrier FLO_LFY PF01698.11 CDI86678.1 - 1 8.1 22.9 2.1 7.1 0.8 2.2 2 0 0 2 2 2 0 Floricaula / Leafy protein Dala_Dala_lig_N PF01820.16 CDI86678.1 - 1.4 9.2 11.9 6.8 7.0 3.3 2.7 2 0 0 2 2 2 0 D-ala D-ala ligase N-terminus DUF2828 PF11443.3 CDI86678.1 - 1.5 6.9 16.6 0.22 9.6 5.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF2828) SID-1_RNA_chan PF13965.1 CDI86678.1 - 1.5 6.8 12.9 0.036 12.2 2.9 2.0 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 FAM60A PF15396.1 CDI86678.1 - 2 8.0 15.9 1.2 8.8 3.8 2.2 2 0 0 2 2 2 0 Protein Family FAM60A Plasmodium_Vir PF05795.6 CDI86678.1 - 2.8 7.0 11.4 0.78 8.8 1.1 2.1 2 0 0 2 2 2 0 Plasmodium vivax Vir protein DUF2215 PF10225.4 CDI86678.1 - 2.8 7.3 11.2 2.3 7.6 4.1 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2215) TRAP_alpha PF03896.11 CDI86678.1 - 2.9 6.7 12.8 0.29 10.1 2.9 2.4 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit DUF4446 PF14584.1 CDI86678.1 - 3.1 7.6 14.6 5.5 6.7 6.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) GPCR_chapero_1 PF11904.3 CDI86678.1 - 3.2 6.8 16.4 1.8 7.6 4.9 2.1 2 0 0 2 2 2 0 GPCR-chaperone eIF-3_zeta PF05091.7 CDI86678.1 - 4.4 5.8 26.5 0.6 8.6 8.5 2.1 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Hid1 PF12722.2 CDI86678.1 - 6.4 4.3 25.8 2.7 5.5 8.7 2.0 2 0 0 2 2 2 0 High-temperature-induced dauer-formation protein DUF1777 PF08648.7 CDI86678.1 - 7.4 6.2 16.3 3.4 7.3 6.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1777) PBP1_TM PF14812.1 CDI86678.1 - 8.4 6.7 12.9 0.8 10.0 3.0 2.2 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF1510 PF07423.6 CDI86678.1 - 9.9 5.4 34.5 0.22 10.8 10.2 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1510) Chromo PF00385.19 CDI86680.1 - 2.2e-13 49.6 0.0 4.9e-13 48.5 0.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain rve PF00665.21 CDI86680.1 - 0.012 15.6 0.0 0.026 14.6 0.0 1.6 1 0 0 1 1 1 0 Integrase core domain gag-asp_proteas PF13975.1 CDI86681.1 - 1.1e-10 41.1 0.0 2.4e-10 40.0 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVT_1 PF00078.22 CDI86681.1 - 1.4e-08 34.4 0.0 2.3e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.1 CDI86681.1 - 1.7e-08 34.8 0.0 7e-08 32.8 0.0 2.0 2 0 0 2 2 2 1 Aspartyl protease RVP_2 PF08284.6 CDI86681.1 - 0.0008 19.3 0.0 0.0015 18.4 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease RVP PF00077.15 CDI86681.1 - 0.0013 18.6 0.0 0.0086 15.9 0.0 2.2 1 1 0 1 1 1 1 Retroviral aspartyl protease zf-CCHC PF00098.18 CDI86682.1 - 0.0033 17.2 7.1 0.51 10.3 0.1 2.4 2 0 0 2 2 2 2 Zinc knuckle DnaJ_CXXCXGXG PF00684.14 CDI86682.1 - 0.025 14.6 1.7 0.044 13.8 1.2 1.4 1 0 0 1 1 1 0 DnaJ central domain CCDC155 PF14662.1 CDI86683.1 - 0.092 12.3 0.1 0.12 11.9 0.1 1.1 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 Pkinase PF00069.20 CDI86685.1 - 4e-34 117.9 0.0 4e-34 117.9 0.0 4.9 5 3 0 5 5 5 1 Protein kinase domain P12 PF12669.2 CDI86686.1 - 4.9 7.4 8.2 6.4 7.0 0.0 2.4 2 0 0 2 2 2 0 Virus attachment protein p12 family DUF572 PF04502.8 CDI86686.1 - 8.6 5.4 15.4 9.5 5.3 10.7 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF572) PP2C PF00481.16 CDI86688.1 - 0.0012 18.2 0.6 0.0015 18.0 0.4 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C Activator_LAG-3 PF11498.3 CDI86688.1 - 0.0057 15.4 17.8 0.0058 15.4 12.4 1.2 1 0 0 1 1 1 1 Transcriptional activator LAG-3 DUF4175 PF13779.1 CDI86688.1 - 0.02 12.6 13.7 0.02 12.5 9.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) PAT1 PF09770.4 CDI86688.1 - 0.024 12.8 12.2 0.025 12.8 8.5 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Med15 PF09606.5 CDI86688.1 - 0.03 12.5 20.3 0.029 12.5 14.1 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal FimP PF09766.4 CDI86688.1 - 0.046 12.7 8.0 0.047 12.7 5.6 1.1 1 0 0 1 1 1 0 Fms-interacting protein HMG14_17 PF01101.13 CDI86688.1 - 0.056 14.1 2.6 0.082 13.6 1.8 1.3 1 0 0 1 1 1 0 HMG14 and HMG17 Spt20 PF12090.3 CDI86688.1 - 0.17 11.2 5.0 0.18 11.1 3.4 1.1 1 0 0 1 1 1 0 Spt20 family DUF4647 PF15504.1 CDI86688.1 - 0.17 10.6 6.3 0.19 10.5 4.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4647) Suf PF05843.9 CDI86688.1 - 0.23 11.1 5.6 0.22 11.1 3.9 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) BRF1 PF07741.8 CDI86688.1 - 0.59 10.3 9.9 0.93 9.7 6.8 1.3 1 0 0 1 1 1 0 Brf1-like TBP-binding domain Serinc PF03348.10 CDI86688.1 - 0.6 8.7 3.0 0.53 8.9 2.1 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) GET2 PF08690.5 CDI86688.1 - 1.1 8.4 8.8 1.1 8.4 6.1 1.0 1 0 0 1 1 1 0 GET complex subunit GET2 DUF4557 PF15101.1 CDI86688.1 - 1.7 8.4 11.1 2.1 8.1 7.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) Utp14 PF04615.8 CDI86689.1 - 0.69 8.0 52.5 0.83 7.7 36.4 1.0 1 0 0 1 1 1 0 Utp14 protein DUF572 PF04502.8 CDI86690.1 - 1.1 8.4 16.3 1.4 8.0 11.3 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF605 PF04652.11 CDI86690.1 - 2.5 7.4 21.9 3.1 7.0 15.2 1.1 1 0 0 1 1 1 0 Vta1 like Macoilin PF09726.4 CDI86690.1 - 2.9 6.0 18.3 3.4 5.8 12.7 1.2 1 0 0 1 1 1 0 Transmembrane protein DUF1675 PF07897.6 CDI86690.1 - 3.4 7.4 15.1 4.9 6.9 10.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) ArsA_ATPase PF02374.10 CDI86691.1 - 3.7e-39 134.5 0.0 4.3e-39 134.3 0.0 1.0 1 0 0 1 1 1 1 Anion-transporting ATPase CbiA PF01656.18 CDI86691.1 - 4.8e-12 45.6 0.0 5.3e-12 45.5 0.0 1.1 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 CDI86691.1 - 4.7e-07 29.8 0.0 6e-07 29.5 0.0 1.2 1 0 0 1 1 1 1 AAA domain Fer4_NifH PF00142.13 CDI86691.1 - 2.3e-06 27.0 0.0 2.8e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_19 PF13245.1 CDI86691.1 - 0.00037 20.1 0.0 0.00057 19.5 0.0 1.4 1 0 0 1 1 1 1 Part of AAA domain SRP54 PF00448.17 CDI86691.1 - 0.001 18.5 0.0 0.0012 18.3 0.0 1.2 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain NB-ARC PF00931.17 CDI86691.1 - 0.0032 16.3 0.1 0.0043 15.9 0.0 1.1 1 0 0 1 1 1 1 NB-ARC domain IstB_IS21 PF01695.12 CDI86691.1 - 0.004 16.5 0.0 0.0055 16.1 0.0 1.2 1 0 0 1 1 1 1 IstB-like ATP binding protein T2SE PF00437.15 CDI86691.1 - 0.0074 15.2 0.1 0.0095 14.8 0.0 1.1 1 0 0 1 1 1 1 Type II/IV secretion system protein MipZ PF09140.6 CDI86691.1 - 0.015 14.4 0.0 0.015 14.4 0.0 1.2 1 0 0 1 1 1 0 ATPase MipZ Zeta_toxin PF06414.7 CDI86691.1 - 0.015 14.4 0.0 0.019 14.0 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin ResIII PF04851.10 CDI86691.1 - 0.019 14.7 0.0 0.021 14.6 0.0 1.1 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit APS_kinase PF01583.15 CDI86691.1 - 0.02 14.5 0.0 0.031 13.9 0.0 1.2 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_18 PF13238.1 CDI86691.1 - 0.024 14.9 0.0 0.028 14.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain YhjQ PF06564.7 CDI86691.1 - 0.029 13.7 0.0 0.034 13.4 0.0 1.1 1 0 0 1 1 1 0 YhjQ protein AAA_25 PF13481.1 CDI86691.1 - 0.03 13.7 0.0 0.03 13.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain VirC1 PF07015.6 CDI86691.1 - 0.039 13.0 0.0 0.059 12.4 0.0 1.2 1 0 0 1 1 1 0 VirC1 protein AAA_16 PF13191.1 CDI86691.1 - 0.043 13.7 0.0 0.043 13.7 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.22 CDI86691.1 - 0.048 13.9 0.0 0.054 13.7 0.0 1.1 1 0 0 1 1 1 0 ABC transporter NACHT PF05729.7 CDI86691.1 - 0.062 12.9 0.6 0.13 11.9 0.4 1.5 1 1 0 1 1 1 0 NACHT domain AAA_17 PF13207.1 CDI86691.1 - 0.081 13.7 0.3 0.1 13.3 0.2 1.3 1 1 0 1 1 1 0 AAA domain PIF1 PF05970.9 CDI86691.1 - 0.15 10.9 0.0 0.21 10.4 0.0 1.1 1 0 0 1 1 1 0 PIF1-like helicase DUF4650 PF15509.1 CDI86693.1 - 0.057 12.3 17.8 0.059 12.2 12.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4650) DOCK-C2 PF14429.1 CDI86693.1 - 0.08 12.5 4.8 0.096 12.3 3.3 1.1 1 0 0 1 1 1 0 C2 domain in Dock180 and Zizimin proteins Peptidase_C37 PF05416.7 CDI86693.1 - 0.15 10.3 4.8 0.16 10.2 3.3 1.0 1 0 0 1 1 1 0 Southampton virus-type processing peptidase ABC2_membrane_2 PF12679.2 CDI86693.1 - 1.1 8.0 4.1 1.3 7.8 2.8 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF605 PF04652.11 CDI86693.1 - 1.3 8.3 23.4 1.3 8.2 16.2 1.2 1 0 0 1 1 1 0 Vta1 like Spore_coat_CotO PF14153.1 CDI86693.1 - 1.3 8.4 29.9 1.3 8.4 20.7 1.1 1 0 0 1 1 1 0 Spore coat protein CotO DUF4175 PF13779.1 CDI86693.1 - 1.4 6.5 50.1 1.6 6.3 34.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Daxx PF03344.10 CDI86693.1 - 1.4 7.3 19.6 1.4 7.2 13.6 1.0 1 0 0 1 1 1 0 Daxx Family eIF-3_zeta PF05091.7 CDI86693.1 - 1.5 7.3 22.1 1.5 7.3 15.3 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) PAT1 PF09770.4 CDI86693.1 - 1.5 6.9 44.9 1.6 6.9 31.2 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Afaf PF15339.1 CDI86693.1 - 1.8 8.1 7.0 2.2 7.8 4.9 1.2 1 0 0 1 1 1 0 Acrosome formation-associated factor Pox_Ag35 PF03286.9 CDI86693.1 - 1.8 8.0 13.6 2 7.9 9.5 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DDRGK PF09756.4 CDI86693.1 - 2.6 7.3 28.4 3.1 7.1 19.7 1.2 1 0 0 1 1 1 0 DDRGK domain Draxin PF15550.1 CDI86693.1 - 2.8 7.5 15.4 3.2 7.3 10.7 1.2 1 0 0 1 1 1 0 Draxin BTV_NS2 PF04514.7 CDI86693.1 - 3.6 6.3 16.9 3.7 6.3 11.7 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Hid1 PF12722.2 CDI86693.1 - 3.7 5.1 22.8 3.8 5.0 15.8 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein NPR3 PF03666.8 CDI86693.1 - 3.9 5.9 18.6 4.6 5.6 12.9 1.3 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Protocadherin PF08374.6 CDI86693.1 - 5 6.7 14.8 5.9 6.4 10.3 1.1 1 0 0 1 1 1 0 Protocadherin MMR1 PF08505.5 CDI86693.1 - 5 7.0 28.6 5.1 7.0 19.9 1.1 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein Presenilin PF01080.12 CDI86693.1 - 5.4 5.7 13.0 5.5 5.7 9.0 1.1 1 0 0 1 1 1 0 Presenilin Band_3_cyto PF07565.8 CDI86693.1 - 5.6 6.3 20.1 6.6 6.1 13.9 1.3 1 0 0 1 1 1 0 Band 3 cytoplasmic domain TT_ORF1 PF02956.9 CDI86693.1 - 5.9 5.2 14.9 6 5.2 10.3 1.0 1 0 0 1 1 1 0 TT viral orf 1 Cellulose_synt PF03552.9 CDI86693.1 - 6.6 4.8 11.5 7.1 4.7 8.0 1.0 1 0 0 1 1 1 0 Cellulose synthase Herpes_env PF01673.13 CDI86693.1 - 7 5.0 18.3 7.3 5.0 12.7 1.0 1 0 0 1 1 1 0 Herpesvirus putative major envelope glycoprotein DHHW PF14286.1 CDI86693.1 - 7.1 5.8 16.8 7.1 5.8 11.7 1.1 1 0 0 1 1 1 0 DHHW protein HCO3_cotransp PF00955.16 CDI86693.1 - 7.6 5.0 7.8 8.7 4.8 5.4 1.0 1 0 0 1 1 1 0 HCO3- transporter family SAGA-Tad1 PF12767.2 CDI86693.1 - 7.6 6.1 22.0 10 5.7 15.3 1.3 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit SRP-alpha_N PF04086.8 CDI86693.1 - 8.4 5.6 21.9 8.7 5.6 15.2 1.0 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal CDC45 PF02724.9 CDI86693.1 - 8.4 4.2 17.8 8.3 4.3 12.3 1.1 1 0 0 1 1 1 0 CDC45-like protein Med15 PF09606.5 CDI86693.1 - 8.6 4.4 64.4 9.4 4.2 44.6 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Alg14 PF08660.6 CDI86693.1 - 9 6.2 6.5 9.8 6.1 4.5 1.2 1 0 0 1 1 1 0 Oligosaccharide biosynthesis protein Alg14 like DUF755 PF05501.6 CDI86694.1 - 0.018 15.0 18.5 0.018 15.0 12.8 5.5 2 1 3 5 5 5 0 Domain of unknown function (DUF755) RAP1 PF07218.6 CDI86694.1 - 0.13 10.3 7.1 0.16 10.0 5.0 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Erp_C PF06780.6 CDI86694.1 - 6 6.6 12.2 0.25 11.1 1.0 2.5 1 1 1 2 2 2 0 Erp protein C-terminus VIT1 PF01988.14 CDI86695.1 - 0.0016 17.9 0.0 0.0019 17.7 0.0 1.0 1 0 0 1 1 1 1 VIT family CD20 PF04103.10 CDI86695.1 - 0.022 14.6 1.2 0.026 14.4 0.9 1.1 1 0 0 1 1 1 0 CD20-like family Gti1_Pac2 PF09729.4 CDI86695.1 - 0.038 13.8 1.1 0.045 13.6 0.8 1.1 1 0 0 1 1 1 0 Gti1/Pac2 family FimP PF09766.4 CDI86695.1 - 0.075 12.0 10.6 0.075 12.0 7.4 1.0 1 0 0 1 1 1 0 Fms-interacting protein LCE PF14672.1 CDI86695.1 - 0.12 12.8 1.0 0.14 12.6 0.7 1.1 1 0 0 1 1 1 0 Late cornified envelope Spt20 PF12090.3 CDI86695.1 - 0.12 11.7 7.4 0.12 11.6 5.1 1.1 1 0 0 1 1 1 0 Spt20 family DUF4199 PF13858.1 CDI86695.1 - 0.13 12.1 2.5 0.13 12.1 1.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) Insulin PF00049.13 CDI86695.1 - 0.14 12.9 3.3 0.17 12.7 2.3 1.1 1 0 0 1 1 1 0 Insulin/IGF/Relaxin family MRF_C2 PF13888.1 CDI86695.1 - 0.15 11.8 4.6 0.15 11.8 3.2 1.0 1 0 0 1 1 1 0 Myelin gene regulatory factor C-terminal domain 2 Med3 PF11593.3 CDI86695.1 - 0.16 11.1 17.2 0.17 11.0 11.9 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Zip PF02535.17 CDI86695.1 - 0.19 10.7 1.5 0.18 10.7 1.0 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter CPSF73-100_C PF11718.3 CDI86695.1 - 0.2 11.0 4.1 0.2 10.9 2.9 1.1 1 0 0 1 1 1 0 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Suf PF05843.9 CDI86695.1 - 0.26 10.9 9.0 0.26 10.9 6.2 1.0 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF2489 PF10675.4 CDI86695.1 - 0.27 10.8 8.9 0.41 10.3 6.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2489) PAT1 PF09770.4 CDI86695.1 - 0.33 9.1 20.2 0.32 9.1 14.0 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 OATP PF03137.15 CDI86695.1 - 0.34 8.9 4.7 0.34 8.9 3.3 1.0 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family RAB3GAP2_N PF14655.1 CDI86695.1 - 0.38 9.6 6.1 0.42 9.5 4.2 1.2 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus DivIC PF04977.10 CDI86695.1 - 0.47 9.9 10.6 0.61 9.6 7.3 1.1 1 0 0 1 1 1 0 Septum formation initiator DUF788 PF05620.6 CDI86695.1 - 0.51 10.1 5.3 0.58 9.9 3.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF788) DUF2393 PF09624.5 CDI86695.1 - 0.71 9.3 5.3 0.86 9.1 3.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2393) DUF912 PF06024.7 CDI86695.1 - 0.73 9.9 4.2 0.88 9.6 2.9 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF3043 PF11241.3 CDI86695.1 - 0.76 9.3 3.2 0.85 9.1 2.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) Pex14_N PF04695.8 CDI86695.1 - 1 9.4 11.2 1 9.3 7.8 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Serinc PF03348.10 CDI86695.1 - 1 7.9 4.7 1.1 7.8 3.2 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) RRP14 PF15459.1 CDI86695.1 - 1.6 8.8 8.4 2.4 8.2 5.8 1.3 1 0 0 1 1 1 0 60S ribosome biogenesis protein Rrp14 SHR3_chaperone PF08229.6 CDI86695.1 - 2.4 7.0 8.2 3 6.7 5.7 1.1 1 0 0 1 1 1 0 ER membrane protein SH3 DUF4557 PF15101.1 CDI86695.1 - 2.8 7.7 11.5 2.9 7.6 8.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) HD-ZIP_N PF04618.7 CDI86695.1 - 3.8 8.0 5.4 4.2 7.9 3.7 1.1 1 0 0 1 1 1 0 HD-ZIP protein N terminus DUF1071 PF06378.6 CDI86695.1 - 5.3 6.1 8.7 6.4 5.8 6.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1071) Gag_spuma PF03276.9 CDI86695.1 - 5.9 5.1 13.8 6.1 5.0 9.5 1.0 1 0 0 1 1 1 0 Spumavirus gag protein UPF0560 PF10577.4 CDI86695.1 - 6.1 4.9 12.9 6 4.9 8.9 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Med15 PF09606.5 CDI86695.1 - 8.8 4.3 29.9 8.7 4.4 20.7 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF755 PF05501.6 CDI86696.1 - 0.016 15.3 35.2 0.016 15.3 24.4 4.4 1 1 2 3 3 3 0 Domain of unknown function (DUF755) DUF605 PF04652.11 CDI86696.1 - 0.02 14.2 27.2 0.052 12.9 18.9 1.8 1 0 0 1 1 1 0 Vta1 like RAP1 PF07218.6 CDI86696.1 - 0.12 10.4 14.2 0.18 9.8 9.9 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DUF2217 PF10265.4 CDI86696.1 - 6.1 5.4 22.8 11 4.5 15.8 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) CDK2AP PF09806.4 CDI86697.1 - 0.008 16.4 14.6 0.009 16.2 10.1 1.0 1 0 0 1 1 1 1 Cyclin-dependent kinase 2-associated protein BAF1_ABF1 PF04684.8 CDI86697.1 - 0.014 14.2 13.1 0.018 13.9 9.1 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Pex14_N PF04695.8 CDI86697.1 - 0.059 13.4 7.4 0.075 13.0 5.1 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Med15 PF09606.5 CDI86697.1 - 0.43 8.7 17.7 0.42 8.7 12.3 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Hid1 PF12722.2 CDI86697.1 - 1.1 6.8 5.9 1.2 6.7 4.1 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein RAB3GAP2_N PF14655.1 CDI86697.1 - 1.5 7.7 5.3 1.5 7.7 3.7 1.1 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus LpxK PF02606.9 CDI86697.1 - 1.8 7.4 5.6 2.2 7.1 3.9 1.0 1 0 0 1 1 1 0 Tetraacyldisaccharide-1-P 4'-kinase Spt20 PF12090.3 CDI86697.1 - 2 7.7 5.9 2 7.7 4.1 1.1 1 0 0 1 1 1 0 Spt20 family CDK5_activator PF03261.10 CDI86697.1 - 2.2 7.5 7.5 2.3 7.4 5.2 1.0 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein PAT1 PF09770.4 CDI86697.1 - 5.2 5.1 16.2 5.7 5.0 11.2 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF853 PF05872.7 CDI86697.1 - 5.9 5.1 9.4 6.4 4.9 6.5 1.0 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) Totivirus_coat PF05518.6 CDI86697.1 - 6.8 4.3 12.9 7.4 4.2 9.0 1.0 1 0 0 1 1 1 0 Totivirus coat protein Mucin PF01456.12 CDI86697.1 - 8.4 6.1 14.2 9.7 5.9 9.8 1.0 1 0 0 1 1 1 0 Mucin-like glycoprotein TraX PF05857.6 CDI86698.1 - 0.26 10.8 0.0 0.48 10.0 0.0 1.3 1 0 0 1 1 1 0 TraX protein DUF2117 PF09890.4 CDI86699.1 - 0.07 12.3 0.7 0.31 10.2 0.2 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2117) YhfT PF10797.4 CDI86699.1 - 0.15 10.8 1.8 1.2 7.9 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function Phos_pyr_kin PF08543.7 CDI86700.1 - 3e-06 26.6 0.0 3e-06 26.6 0.0 2.9 3 1 1 4 4 4 1 Phosphomethylpyrimidine kinase Spore_YhcN_YlaJ PF09580.5 CDI86700.1 - 0.00065 19.8 6.4 0.00065 19.8 4.5 2.5 2 0 0 2 2 2 1 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) Ribosomal_S11 PF00411.14 CDI86700.1 - 0.18 12.0 0.1 0.18 12.0 0.1 3.6 4 0 0 4 4 4 0 Ribosomal protein S11 DRY_EERY PF09750.4 CDI86700.1 - 0.4 10.7 19.6 3.1 7.9 10.0 2.6 2 0 0 2 2 2 0 Alternative splicing regulator CBP4 PF07960.6 CDI86700.1 - 0.75 9.4 28.8 0.25 10.9 10.9 2.4 2 0 0 2 2 2 0 CBP4 Tau95 PF09734.4 CDI86700.1 - 1.6 7.9 10.7 2 7.6 0.0 2.1 1 1 0 2 2 2 0 RNA polymerase III transcription factor (TF)IIIC subunit GAGA_bind PF06217.7 CDI86700.1 - 2.4 8.0 19.3 4.7 7.0 10.5 2.2 2 0 0 2 2 2 0 GAGA binding protein-like family RskA PF10099.4 CDI86701.1 - 0.018 14.7 5.8 0.022 14.5 4.0 1.1 1 0 0 1 1 1 0 Anti-sigma-K factor rskA Mucin PF01456.12 CDI86701.1 - 0.024 14.4 3.0 0.024 14.4 2.1 2.0 1 1 1 2 2 2 0 Mucin-like glycoprotein PH_10 PF15411.1 CDI86701.1 - 1.1 9.4 6.3 0.17 12.1 1.8 1.6 1 1 1 2 2 2 0 Pleckstrin homology domain SR-25 PF10500.4 CDI86701.1 - 3.2 7.1 16.6 6.2 6.2 11.5 1.4 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein Herpes_UL87 PF03043.9 CDI86701.1 - 5.9 5.1 9.1 6.6 4.9 6.3 1.0 1 0 0 1 1 1 0 Herpesvirus UL87 family TAF1D PF15333.1 CDI86701.1 - 8 6.1 10.7 13 5.4 7.4 1.3 1 1 0 1 1 1 0 TATA box-binding protein-associated factor 1D Plasmid_RAQPRD PF09686.5 CDI86702.1 - 0.01 15.9 0.4 0.01 15.9 0.3 2.2 2 0 0 2 2 2 0 Plasmid protein of unknown function (Plasmid_RAQPRD) SMAP PF15477.1 CDI86702.1 - 0.056 13.7 0.2 0.11 12.8 0.2 1.7 1 1 0 1 1 1 0 Small acidic protein family DUF72 PF01904.13 CDI86702.1 - 0.11 12.2 1.1 0.13 12.0 0.7 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF72 zf-C4H2 PF10146.4 CDI86702.1 - 0.47 10.4 2.4 0.64 9.9 1.7 1.3 1 0 0 1 1 1 0 Zinc finger-containing protein tRNA-synt_His PF13393.1 CDI86702.1 - 0.5 9.3 5.4 0.58 9.1 3.7 1.0 1 0 0 1 1 1 0 Histidyl-tRNA synthetase Med3 PF11593.3 CDI86702.1 - 0.59 9.3 10.5 0.75 8.9 7.3 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DUF2360 PF10152.4 CDI86702.1 - 0.79 10.0 7.4 1.1 9.5 5.1 1.2 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) MSP1_C PF07462.6 CDI86702.1 - 1.1 7.5 8.9 1.1 7.5 6.2 1.1 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus DUF4139 PF13598.1 CDI86702.1 - 1.2 8.3 7.3 1.4 8.1 5.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4139) DUF3993 PF13158.1 CDI86704.1 - 0.79 9.5 4.3 3.9 7.3 0.5 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3993) Hid1 PF12722.2 CDI86705.1 - 1.1 6.8 3.4 1.3 6.6 2.3 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Dehydrin PF00257.14 CDI86705.1 - 2.9 8.2 10.4 5.6 7.2 7.2 1.5 1 0 0 1 1 1 0 Dehydrin LELP1 PF15042.1 CDI86705.1 - 8.2 6.6 9.8 0.79 9.9 2.3 2.2 2 0 0 2 2 2 0 Late cornified envelope-like proline-rich protein 1 FimP PF09766.4 CDI86706.1 - 0.0031 16.6 8.8 0.0031 16.6 6.1 3.6 4 0 0 4 4 4 2 Fms-interacting protein Suf PF05843.9 CDI86706.1 - 0.0057 16.4 6.3 0.0057 16.4 4.4 3.7 3 1 0 3 3 3 2 Suppressor of forked protein (Suf) Topoisom_bac PF01131.15 CDI86707.1 - 7.8e-77 258.7 0.0 3.2e-75 253.4 0.0 2.2 1 1 0 1 1 1 1 DNA topoisomerase Toprim PF01751.17 CDI86707.1 - 6.4e-14 51.7 0.0 1.2e-13 50.8 0.0 1.5 1 0 0 1 1 1 1 Toprim domain NPV_P10 PF05531.7 CDI86709.1 - 0.14 12.3 0.2 0.14 12.3 0.1 4.8 6 0 0 6 6 6 0 Nucleopolyhedrovirus P10 protein Kinesin-relat_1 PF12711.2 CDI86710.1 - 0.008 16.5 1.0 0.018 15.3 0.7 1.6 1 0 0 1 1 1 1 Kinesin motor DNA_pol3_delt_C PF14840.1 CDI86710.1 - 0.1 12.7 1.6 0.2 11.7 1.1 1.4 1 0 0 1 1 1 0 Processivity clamp loader gamma complex DNA pol III C-term IlvC PF01450.14 CDI86711.1 - 0.014 15.3 0.4 0.014 15.3 0.3 2.6 3 0 0 3 3 3 0 Acetohydroxy acid isomeroreductase, catalytic domain DUF3673 PF12425.3 CDI86711.1 - 0.035 13.9 1.0 0.32 10.8 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3673) DUF904 PF06005.7 CDI86712.1 - 2.5 8.4 14.5 0.87 9.9 5.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF904) ASFV_J13L PF05568.6 CDI86712.1 - 3.9 6.9 12.5 0.035 13.6 0.6 2.4 1 1 1 2 2 2 0 African swine fever virus J13L protein DSPc PF00782.15 CDI86713.1 - 0.0035 16.9 0.0 0.0052 16.3 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain TetR_C PF02909.12 CDI86715.1 - 0.028 14.0 0.8 0.064 12.9 0.6 1.6 1 0 0 1 1 1 0 Tetracyclin repressor, C-terminal all-alpha domain Phage_Mu_Gam PF07352.7 CDI86716.1 - 0.0097 15.4 3.8 0.014 14.9 2.7 1.2 1 0 0 1 1 1 1 Bacteriophage Mu Gam like protein USP8_interact PF08941.5 CDI86716.1 - 0.017 14.4 3.3 0.017 14.4 2.3 1.5 2 0 0 2 2 2 0 USP8 interacting Microtub_assoc PF07989.6 CDI86716.1 - 0.025 14.3 1.7 0.025 14.3 1.2 2.3 2 1 0 2 2 2 0 Microtubule associated HAUS6_N PF14661.1 CDI86716.1 - 0.063 12.6 5.8 0.079 12.3 4.0 1.0 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus BOP1NT PF08145.7 CDI86716.1 - 0.068 12.9 1.8 0.092 12.4 1.2 1.2 1 0 0 1 1 1 0 BOP1NT (NUC169) domain SpoU_sub_bind PF08032.7 CDI86716.1 - 0.11 12.6 1.4 0.22 11.6 0.3 1.9 1 1 1 2 2 2 0 RNA 2'-O ribose methyltransferase substrate binding Ada3 PF10198.4 CDI86716.1 - 0.17 11.6 5.1 0.24 11.1 3.5 1.3 1 0 0 1 1 1 0 Histone acetyltransferases subunit 3 LRS4 PF10422.4 CDI86716.1 - 0.19 11.0 8.9 0.22 10.8 6.2 1.2 1 0 0 1 1 1 0 Monopolin complex subunit LRS4 DUF4549 PF15082.1 CDI86716.1 - 0.58 9.7 6.1 0.21 11.2 1.9 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4549) Atg14 PF10186.4 CDI86716.1 - 1.3 7.8 13.9 1.6 7.6 9.7 1.0 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 HALZ PF02183.13 CDI86716.1 - 1.5 8.5 13.5 1.3 8.7 0.4 3.3 1 1 3 4 4 4 0 Homeobox associated leucine zipper DUF904 PF06005.7 CDI86716.1 - 1.8 8.9 17.3 3.7e+03 -1.7 12.0 2.5 1 1 0 1 1 1 0 Protein of unknown function (DUF904) TMPIT PF07851.8 CDI86716.1 - 1.9 7.5 6.5 2.2 7.2 4.5 1.1 1 0 0 1 1 1 0 TMPIT-like protein Viral_P18 PF04521.8 CDI86716.1 - 5.8 6.3 9.1 0.41 10.0 1.2 2.1 1 1 1 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein RmuC PF02646.11 CDI86716.1 - 6.2 5.5 14.5 8.2 5.1 2.5 2.0 1 1 1 2 2 2 0 RmuC family TPR_6 PF13174.1 CDI86717.1 - 0.0018 18.6 0.4 1.6 9.3 0.0 4.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 CDI86717.1 - 0.004 17.0 5.8 0.5 10.3 0.3 4.5 3 2 1 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.1 CDI86717.1 - 0.02 15.4 2.0 12 6.8 0.0 4.4 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_11 PF13414.1 CDI86717.1 - 0.021 14.4 4.0 0.25 10.9 0.0 3.4 4 0 0 4 4 4 0 TPR repeat TPR_2 PF07719.12 CDI86717.1 - 0.023 14.6 7.1 0.7 9.9 0.1 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.1 CDI86717.1 - 0.11 12.8 2.0 62 4.0 0.1 4.1 3 1 1 4 4 4 0 Tetratricopeptide repeat PPR PF01535.15 CDI86717.1 - 0.2 11.7 2.4 1.3 9.1 0.0 3.2 3 0 0 3 3 3 0 PPR repeat TPR_3 PF07720.7 CDI86717.1 - 0.27 11.0 3.5 2 8.3 0.2 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat Glucos_trans_II PF14264.1 CDI86718.1 - 0.041 12.8 3.1 0.038 12.9 1.2 1.5 1 1 0 1 1 1 0 Glucosyl transferase GtrII PIRT PF15099.1 CDI86718.1 - 0.043 13.0 2.3 0.14 11.3 1.6 1.9 1 0 0 1 1 1 0 Phosphoinositide-interacting protein family Mac PF12464.3 CDI86718.1 - 0.12 12.3 0.6 0.29 11.1 0.4 1.6 1 0 0 1 1 1 0 Maltose acetyltransferase Claudin_2 PF13903.1 CDI86718.1 - 7.2 6.2 9.3 10 5.7 5.0 2.0 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction TrbC PF04956.8 CDI86719.1 - 0.93 9.5 9.8 4.6 7.3 3.7 3.3 3 0 0 3 3 3 0 TrbC/VIRB2 family LCD1 PF09798.4 CDI86720.1 - 0.39 8.6 4.0 0.6 8.0 2.7 1.3 1 0 0 1 1 1 0 DNA damage checkpoint protein WD40 PF00400.27 CDI86721.1 - 0.012 15.4 0.9 0.12 12.3 0.0 3.0 4 0 0 4 4 4 0 WD domain, G-beta repeat SR-25 PF10500.4 CDI86722.1 - 0.0022 17.5 4.2 0.0022 17.5 2.9 13.5 9 5 1 11 11 11 5 Nuclear RNA-splicing-associated protein DUF4207 PF13904.1 CDI86723.1 - 0.0012 18.3 0.5 0.0012 18.3 0.4 11.4 6 3 3 10 10 10 3 Domain of unknown function (DUF4207) BAF1_ABF1 PF04684.8 CDI86724.1 - 0.0051 15.7 13.9 0.0057 15.5 9.6 1.1 1 0 0 1 1 1 1 BAF1 / ABF1 chromatin reorganising factor CDK2AP PF09806.4 CDI86724.1 - 0.032 14.4 18.1 0.034 14.3 12.6 1.0 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein Chorion_2 PF03964.10 CDI86724.1 - 0.043 14.3 3.3 0.05 14.1 2.3 1.1 1 0 0 1 1 1 0 Chorion family 2 Myco_19_kDa PF05481.7 CDI86724.1 - 0.23 11.2 3.0 0.25 11.1 2.0 1.1 1 0 0 1 1 1 0 Mycobacterium 19 kDa lipoprotein antigen eIF3_N PF09440.5 CDI86724.1 - 0.26 11.4 4.0 0.67 10.1 0.3 2.0 2 0 0 2 2 2 0 eIF3 subunit 6 N terminal domain SR-25 PF10500.4 CDI86724.1 - 0.52 9.7 8.9 0.62 9.5 6.2 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Tetraspannin PF00335.15 CDI86724.1 - 1 8.6 6.7 0.96 8.6 4.7 1.1 1 0 0 1 1 1 0 Tetraspanin family E_Pc_C PF06752.7 CDI86724.1 - 6.8 6.1 20.6 9.9 5.5 14.3 1.3 1 0 0 1 1 1 0 Enhancer of Polycomb C-terminus BRF1 PF07741.8 CDI86724.1 - 8.6 6.6 8.6 13 6.0 5.9 1.3 1 1 0 1 1 1 0 Brf1-like TBP-binding domain Med12-LCEWAV PF12145.3 CDI86725.1 - 0.0082 14.6 3.8 0.0093 14.4 2.6 1.0 1 0 0 1 1 1 1 Eukaryotic Mediator 12 subunit domain DNA_pol3_a_NII PF11490.3 CDI86725.1 - 0.025 14.1 6.9 0.028 14.0 4.8 1.2 1 0 0 1 1 1 0 DNA polymerase III polC-type N-terminus II DUF4518 PF15008.1 CDI86725.1 - 0.046 12.7 5.6 0.053 12.5 3.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4518) Peptidase_S49_N PF08496.5 CDI86725.1 - 0.051 13.3 3.8 0.058 13.1 2.6 1.0 1 0 0 1 1 1 0 Peptidase family S49 N-terminal RAB3GAP2_N PF14655.1 CDI86725.1 - 0.056 12.4 4.1 0.053 12.5 2.8 1.1 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus FimP PF09766.4 CDI86725.1 - 0.071 12.1 10.5 0.073 12.1 7.3 1.0 1 0 0 1 1 1 0 Fms-interacting protein DUF3141 PF11339.3 CDI86725.1 - 0.081 11.2 2.5 0.087 11.1 1.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3141) Glyco_tranf_2_4 PF13704.1 CDI86725.1 - 0.14 12.5 1.8 0.15 12.3 1.2 1.1 1 0 0 1 1 1 0 Glycosyl transferase family 2 GN3L_Grn1 PF08701.6 CDI86725.1 - 0.16 11.9 9.2 0.2 11.5 6.4 1.1 1 0 0 1 1 1 0 GNL3L/Grn1 putative GTPase Zip PF02535.17 CDI86725.1 - 0.17 10.8 1.3 0.17 10.8 0.9 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter Spt20 PF12090.3 CDI86725.1 - 0.24 10.7 8.4 0.26 10.6 5.8 1.1 1 0 0 1 1 1 0 Spt20 family DUF3518 PF12031.3 CDI86725.1 - 0.26 10.0 3.0 0.3 9.8 2.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3518) Serinc PF03348.10 CDI86725.1 - 0.37 9.4 2.4 0.36 9.5 1.6 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) UPF0560 PF10577.4 CDI86725.1 - 0.45 8.7 12.4 0.43 8.7 8.6 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 FCP1_C PF09309.5 CDI86725.1 - 0.55 9.4 6.8 0.54 9.5 4.7 1.1 1 0 0 1 1 1 0 FCP1, C-terminal DUF788 PF05620.6 CDI86725.1 - 0.68 9.7 3.0 0.68 9.7 2.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF788) ERF PF04404.7 CDI86725.1 - 0.68 9.4 12.1 0.75 9.3 8.4 1.1 1 0 0 1 1 1 0 ERF superfamily Band_3_cyto PF07565.8 CDI86725.1 - 0.99 8.8 6.1 1 8.7 4.3 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain EIIBC-GUT_N PF03612.9 CDI86725.1 - 1.2 8.7 4.1 1.3 8.5 2.9 1.0 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus DUF4175 PF13779.1 CDI86725.1 - 1.3 6.6 21.6 1.3 6.6 15.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Suf PF05843.9 CDI86725.1 - 1.4 8.5 10.0 1.5 8.4 6.9 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) G0-G1_switch_2 PF15103.1 CDI86725.1 - 1.7 8.8 4.7 1.9 8.7 3.2 1.1 1 0 0 1 1 1 0 G0/G1 switch protein 2 Activator_LAG-3 PF11498.3 CDI86725.1 - 3.9 6.1 34.2 4.3 5.9 23.7 1.0 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Med15 PF09606.5 CDI86725.1 - 4.3 5.4 25.7 4.6 5.3 17.8 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal SHR3_chaperone PF08229.6 CDI86725.1 - 5.1 6.0 7.5 5.8 5.8 5.2 1.1 1 0 0 1 1 1 0 ER membrane protein SH3 DUF4557 PF15101.1 CDI86725.1 - 7.4 6.3 14.8 8.2 6.2 10.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) Ribosomal_60s PF00428.14 CDI86726.1 - 8.4 6.8 12.2 22 5.5 8.5 1.7 1 0 0 1 1 1 0 60s Acidic ribosomal protein Med15 PF09606.5 CDI86727.1 - 0.0001 20.7 19.6 0.0001 20.7 13.6 5.1 4 2 1 5 5 5 1 ARC105 or Med15 subunit of Mediator complex non-fungal SR-25 PF10500.4 CDI86727.1 - 0.00023 20.7 12.9 0.00023 20.7 8.9 8.6 5 4 3 8 8 8 1 Nuclear RNA-splicing-associated protein AAA_11 PF13086.1 CDI86727.1 - 0.006 16.1 34.9 0.44 10.0 3.4 3.6 3 0 0 3 3 3 3 AAA domain AAA_23 PF13476.1 CDI86727.1 - 0.14 12.4 44.1 0.02 15.2 2.5 3.2 3 0 0 3 3 3 0 AAA domain Serinc PF03348.10 CDI86727.1 - 0.14 10.8 39.5 0.12 11.0 4.5 3.8 3 0 0 3 3 3 0 Serine incorporator (Serinc) Herpes_UL87 PF03043.9 CDI86727.1 - 0.19 10.0 33.0 0.86 7.9 10.7 3.4 3 0 0 3 3 3 0 Herpesvirus UL87 family Spore_YhcN_YlaJ PF09580.5 CDI86727.1 - 5.1 7.1 40.1 0.29 11.2 0.4 3.6 3 0 0 3 3 3 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) IncA PF04156.9 CDI86728.1 - 5.4e-06 26.1 22.2 5.4e-06 26.1 15.4 2.9 2 1 1 3 3 1 1 IncA protein SAGA-Tad1 PF12767.2 CDI86728.1 - 2.3e-05 24.2 29.0 3e-05 23.8 20.1 1.2 1 0 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit MIP-T3 PF10243.4 CDI86728.1 - 2.4e-05 23.0 32.7 2.8e-05 22.8 22.7 1.1 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 Ycf1 PF05758.7 CDI86728.1 - 0.0042 14.8 21.2 0.0047 14.7 14.7 1.0 1 0 0 1 1 1 1 Ycf1 Presenilin PF01080.12 CDI86728.1 - 0.0047 15.8 16.9 0.006 15.4 11.7 1.2 1 0 0 1 1 1 1 Presenilin DUF4045 PF13254.1 CDI86728.1 - 0.0093 15.2 23.0 0.01 15.1 16.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4045) PLRV_ORF5 PF01690.12 CDI86728.1 - 0.021 13.9 23.1 0.023 13.8 16.0 1.2 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein CAF-1_p150 PF11600.3 CDI86728.1 - 0.047 13.0 39.6 0.058 12.7 27.4 1.0 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Utp14 PF04615.8 CDI86728.1 - 0.049 11.8 35.1 0.058 11.5 24.3 1.0 1 0 0 1 1 1 0 Utp14 protein Dapper PF15268.1 CDI86728.1 - 0.081 11.7 35.5 0.08 11.7 24.6 1.0 1 0 0 1 1 1 0 Dapper SOBP PF15279.1 CDI86728.1 - 0.087 13.1 28.2 0.12 12.7 19.6 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein Draxin PF15550.1 CDI86728.1 - 0.13 11.9 20.2 0.16 11.6 14.0 1.2 1 0 0 1 1 1 0 Draxin GAGA_bind PF06217.7 CDI86728.1 - 0.13 12.2 30.3 0.16 11.8 21.0 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family 2HCT PF03390.10 CDI86728.1 - 0.36 9.1 3.5 0.28 9.5 0.0 2.0 2 0 0 2 2 2 0 2-hydroxycarboxylate transporter family CDC45 PF02724.9 CDI86728.1 - 0.45 8.4 27.5 0.56 8.1 19.1 1.1 1 0 0 1 1 1 0 CDC45-like protein PAT1 PF09770.4 CDI86728.1 - 0.63 8.2 87.1 0.77 7.9 60.3 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Exonuc_VII_L PF02601.10 CDI86728.1 - 0.74 8.9 26.7 0.84 8.7 18.5 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Peptidase_S64 PF08192.6 CDI86728.1 - 1.3 7.2 21.0 1.6 6.9 14.6 1.0 1 0 0 1 1 1 0 Peptidase family S64 Parvo_coat PF00740.13 CDI86728.1 - 5.3 5.8 34.2 6.5 5.5 23.7 1.1 1 0 0 1 1 1 0 Parvovirus coat protein VP2 LMBR1 PF04791.11 CDI86728.1 - 6.6 5.1 15.1 8.4 4.8 10.4 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Herpes_UL87 PF03043.9 CDI86728.1 - 7.6 4.7 18.9 10 4.3 13.1 1.2 1 0 0 1 1 1 0 Herpesvirus UL87 family FAM60A PF15396.1 CDI86728.1 - 8.4 6.0 28.9 11 5.6 20.1 1.1 1 0 0 1 1 1 0 Protein Family FAM60A Ndc1_Nup PF09531.5 CDI86728.1 - 8.4 4.6 31.1 10 4.3 21.6 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Neur_chan_memb PF02932.11 CDI86728.1 - 8.7 6.1 25.6 12 5.6 17.7 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Pox_Ag35 PF03286.9 CDI86730.1 - 1.3 8.4 22.4 1.1 8.7 8.8 2.0 2 0 0 2 2 2 0 Pox virus Ag35 surface protein SAPS PF04499.10 CDI86730.1 - 1.5 7.3 27.9 2.3 6.7 19.3 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Daxx PF03344.10 CDI86730.1 - 3.1 6.1 32.8 3.8 5.8 22.7 1.0 1 0 0 1 1 1 0 Daxx Family RNA_pol_Rpc4 PF05132.9 CDI86730.1 - 4.2 7.3 30.0 1.8 8.5 2.7 2.3 2 0 0 2 2 2 0 RNA polymerase III RPC4 RIC3 PF15361.1 CDI86730.1 - 5.7 7.1 36.3 4.2 7.5 4.5 2.2 2 0 0 2 2 2 0 Resistance to inhibitors of cholinesterase homologue 3 BORG_CEP PF14957.1 CDI86730.1 - 7.7 7.4 26.0 5 8.0 9.5 2.2 2 0 0 2 2 2 0 Cdc42 effector NPR3 PF03666.8 CDI86730.1 - 9.1 4.6 31.1 2 6.8 12.0 2.0 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 BC10 PF06726.7 CDI86731.1 - 0.18 11.8 1.6 0.47 10.5 1.1 1.7 1 0 0 1 1 1 0 Bladder cancer-related protein BC10 IncA PF04156.9 CDI86732.1 - 6.9e-05 22.5 12.2 6.9e-05 22.5 8.5 5.5 4 1 1 5 5 5 3 IncA protein FimP PF09766.4 CDI86732.1 - 0.0019 17.3 61.8 0.0068 15.5 6.4 4.3 4 0 0 4 4 4 4 Fms-interacting protein SAPS PF04499.10 CDI86732.1 - 0.008 14.8 25.3 1.1 7.8 9.2 3.2 1 1 1 2 2 2 1 SIT4 phosphatase-associated protein Ycf1 PF05758.7 CDI86732.1 - 0.18 9.5 22.2 0.16 9.6 4.4 3.2 3 0 0 3 3 3 0 Ycf1 Med15 PF09606.5 CDI86733.1 - 0.017 13.3 27.1 0.019 13.1 18.8 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal BAF1_ABF1 PF04684.8 CDI86733.1 - 0.022 13.6 15.3 0.028 13.3 10.6 1.3 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Nop25 PF09805.4 CDI86733.1 - 0.052 13.6 10.2 0.068 13.2 7.1 1.2 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) DUF1510 PF07423.6 CDI86733.1 - 0.12 11.6 19.4 0.15 11.3 13.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Neur_chan_memb PF02932.11 CDI86733.1 - 0.14 12.0 17.6 0.16 11.7 12.2 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DNA_pol_viral_N PF00242.12 CDI86733.1 - 0.29 10.1 36.3 0.31 10.0 25.2 1.0 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain FCP1_C PF09309.5 CDI86733.1 - 0.96 8.6 20.2 1.6 7.9 14.0 1.4 1 0 0 1 1 1 0 FCP1, C-terminal Pol_alpha_B_N PF08418.5 CDI86733.1 - 1.4 8.3 28.9 1.6 8.2 20.0 1.1 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal Asp-B-Hydro_N PF05279.6 CDI86733.1 - 1.5 8.6 4.6 1.7 8.4 3.2 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region DUF4175 PF13779.1 CDI86733.1 - 1.9 6.1 20.7 1.9 6.0 14.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Mem_trans PF03547.13 CDI86733.1 - 1.9 6.7 16.5 2.4 6.3 11.4 1.2 1 0 0 1 1 1 0 Membrane transport protein DUF4647 PF15504.1 CDI86733.1 - 1.9 7.2 23.2 2.2 7.0 16.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4647) DUF2217 PF10265.4 CDI86733.1 - 2 7.0 26.4 3.1 6.4 18.3 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) PAT1 PF09770.4 CDI86733.1 - 2.5 6.2 25.3 2.9 6.0 17.6 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TFIIA PF03153.8 CDI86733.1 - 2.6 7.8 26.3 3.1 7.6 18.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF572 PF04502.8 CDI86733.1 - 2.8 7.0 24.6 3.5 6.7 17.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) MAP65_ASE1 PF03999.7 CDI86733.1 - 2.8 6.4 31.9 3.1 6.2 22.1 1.0 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) Utp14 PF04615.8 CDI86733.1 - 3.3 5.7 23.0 3.8 5.5 15.9 1.0 1 0 0 1 1 1 0 Utp14 protein DUF3807 PF12720.2 CDI86733.1 - 3.5 7.7 20.0 4.8 7.2 13.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) SAPS PF04499.10 CDI86733.1 - 3.7 6.0 21.0 4.5 5.7 14.5 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Na_trans_assoc PF06512.8 CDI86733.1 - 5.3 6.9 20.2 7.6 6.4 14.0 1.2 1 0 0 1 1 1 0 Sodium ion transport-associated Menin PF05053.8 CDI86733.1 - 6.1 4.8 17.2 7.1 4.6 11.9 1.0 1 0 0 1 1 1 0 Menin DUF4407 PF14362.1 CDI86733.1 - 8.4 5.2 10.8 9.7 5.0 7.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) MAT1 PF06391.8 CDI86733.1 - 9 5.8 15.4 11 5.5 10.6 1.1 1 0 0 1 1 1 0 CDK-activating kinase assembly factor MAT1 Spc7_N PF15402.1 CDI86733.1 - 9.1 4.1 32.9 10 3.9 22.8 1.0 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 DUF4220 PF13968.1 CDI86734.1 - 7.4 5.5 8.9 7.8 5.4 6.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4220) FAM60A PF15396.1 CDI86734.1 - 7.6 6.2 16.1 11 5.6 11.1 1.3 1 0 0 1 1 1 0 Protein Family FAM60A Spc7_N PF15402.1 CDI86734.1 - 7.7 4.3 20.2 9.5 4.0 14.0 1.1 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 DUF3520 PF12034.3 CDI86734.1 - 9.4 6.3 12.9 12 5.9 8.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3520) PP1_bind PF15276.1 CDI86735.1 - 0.51 10.4 3.0 1.1 9.2 2.1 1.6 1 0 0 1 1 1 0 Protein phosphatase 1 binding SAGA-Tad1 PF12767.2 CDI86735.1 - 0.64 9.6 14.0 0.73 9.4 9.7 1.2 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit Med15 PF09606.5 CDI86735.1 - 0.98 7.5 30.9 1.2 7.2 21.4 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal TFIIA PF03153.8 CDI86735.1 - 10 5.9 30.6 13 5.5 21.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RR_TM4-6 PF06459.7 CDI86736.1 - 0.68 9.7 3.4 0.7 9.7 2.3 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF1020 PF06255.8 CDI86736.1 - 1.2 8.3 8.1 1.3 8.1 5.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1020) AAA_16 PF13191.1 CDI86736.1 - 1.3 8.9 5.8 1.7 8.5 4.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain EspB PF05802.6 CDI86736.1 - 1.5 7.7 17.8 1.8 7.4 12.3 1.1 1 0 0 1 1 1 0 Enterobacterial EspB protein Myc_N PF01056.13 CDI86737.1 - 0.077 12.1 0.3 0.14 11.2 0.2 1.4 1 0 0 1 1 1 0 Myc amino-terminal region PAT1 PF09770.4 CDI86737.1 - 0.27 9.4 17.8 0.37 8.9 12.3 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF2146 PF10220.4 CDI86737.1 - 0.35 8.8 3.5 0.47 8.3 2.4 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2146) DUF2939 PF11159.3 CDI86737.1 - 2.6 8.2 6.7 5.9 7.1 4.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2939) Prothymosin PF03247.9 CDI86737.1 - 5 7.3 15.4 8.3 6.6 10.7 1.2 1 0 0 1 1 1 0 Prothymosin/parathymosin family DUF3313 PF11769.3 CDI86737.1 - 5.3 6.3 6.2 9.2 5.5 4.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3313) Med15 PF09606.5 CDI86738.1 - 3.2 5.8 70.2 3.7 5.6 48.6 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF3801 PF12687.2 CDI86739.1 - 1.5 8.3 21.9 5 6.6 13.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3801) DDRGK PF09756.4 CDI86740.1 - 0.014 14.8 30.3 0.017 14.5 21.0 1.1 1 0 0 1 1 1 0 DDRGK domain Pox_Ag35 PF03286.9 CDI86740.1 - 0.44 10.0 17.4 0.53 9.7 12.0 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Herpes_UL87 PF03043.9 CDI86740.1 - 0.54 8.5 22.9 0.57 8.5 15.9 1.0 1 0 0 1 1 1 0 Herpesvirus UL87 family eIF3_subunit PF08597.5 CDI86740.1 - 0.81 9.2 21.6 0.91 9.0 15.0 1.2 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit eIF-3_zeta PF05091.7 CDI86740.1 - 0.94 8.0 33.5 1.1 7.7 23.2 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF4045 PF13254.1 CDI86740.1 - 2.1 7.5 23.4 2.3 7.4 16.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) DUF4638 PF15472.1 CDI86740.1 - 2.8 7.4 21.2 3.2 7.2 14.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) Bul1_N PF04425.7 CDI86740.1 - 4.9 5.6 30.9 5.4 5.4 21.4 1.0 1 0 0 1 1 1 0 Bul1 N terminus Tim54 PF11711.3 CDI86740.1 - 5.7 5.4 18.4 6 5.3 12.7 1.0 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DUF966 PF06136.8 CDI86740.1 - 5.8 6.2 23.7 6.5 6.0 16.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Glyco_transf_15 PF01793.11 CDI86740.1 - 6.1 5.6 21.8 8.3 5.2 15.1 1.3 1 0 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase Spore_coat_CotO PF14153.1 CDI86740.1 - 6.8 6.0 34.8 8.2 5.8 24.1 1.2 1 0 0 1 1 1 0 Spore coat protein CotO CKAP2_C PF15297.1 CDI86740.1 - 7.6 5.2 26.4 9.8 4.8 18.3 1.1 1 0 0 1 1 1 0 Cytoskeleton-associated protein 2 C-terminus Asp-B-Hydro_N PF05279.6 CDI86740.1 - 8.9 6.0 20.4 10 5.8 14.1 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region PAT1 PF09770.4 CDI86740.1 - 9.4 4.3 54.7 9.9 4.2 37.9 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Paramyxo_ncap PF00973.14 CDI86740.1 - 9.5 4.7 23.5 11 4.5 16.3 1.0 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein GAGA_bind PF06217.7 CDI86740.1 - 9.9 6.0 30.9 11 5.8 21.4 1.0 1 0 0 1 1 1 0 GAGA binding protein-like family DUF1959 PF09218.5 CDI86741.1 - 0.095 12.4 0.0 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1959) RNA_pol_Rpb1_5 PF04998.12 CDI86742.1 - 2.3e-17 63.1 2.1 2.3e-17 63.1 1.5 3.8 2 2 0 2 2 2 1 RNA polymerase Rpb1, domain 5 RAB3GAP2_N PF14655.1 CDI86742.1 - 0.0087 15.1 2.5 0.0087 15.1 1.7 6.0 2 1 2 4 4 4 1 Rab3 GTPase-activating protein regulatory subunit N-terminus Med15 PF09606.5 CDI86742.1 - 0.47 8.5 130.2 1 7.4 7.9 2.2 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal FAD_oxidored PF12831.2 CDI86742.1 - 2.1 7.3 22.0 0.55 9.2 0.0 2.4 2 0 0 2 2 2 0 FAD dependent oxidoreductase Cwf_Cwc_15 PF04889.7 CDI86743.1 - 0.72 9.5 40.1 0.94 9.1 27.8 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein CAF-1_p150 PF11600.3 CDI86743.1 - 1.3 8.3 57.7 1.8 7.8 40.0 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF1510 PF07423.6 CDI86743.1 - 1.6 8.0 50.8 1.9 7.7 35.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) FCP1_C PF09309.5 CDI86743.1 - 5.3 6.2 37.1 7.4 5.7 25.7 1.3 1 0 0 1 1 1 0 FCP1, C-terminal FimP PF09766.4 CDI86744.1 - 0.0019 17.3 6.8 0.0019 17.3 4.7 1.0 1 0 0 1 1 1 1 Fms-interacting protein Sigma70_ner PF04546.8 CDI86744.1 - 0.003 17.2 0.5 0.0032 17.1 0.3 1.0 1 0 0 1 1 1 1 Sigma-70, non-essential region SR-25 PF10500.4 CDI86744.1 - 0.012 15.0 2.4 0.014 14.8 1.7 1.0 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein CDC45 PF02724.9 CDI86744.1 - 0.022 12.8 5.6 0.024 12.6 3.9 1.0 1 0 0 1 1 1 0 CDC45-like protein bZIP_C PF12498.3 CDI86744.1 - 0.04 15.1 2.8 0.039 15.1 1.9 1.1 1 0 0 1 1 1 0 Basic leucine-zipper C terminal PBP1_TM PF14812.1 CDI86744.1 - 0.046 14.0 1.4 0.053 13.8 1.0 1.1 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Myb_Cef PF11831.3 CDI86744.1 - 0.047 12.8 5.3 0.054 12.7 3.7 1.0 1 0 0 1 1 1 0 pre-mRNA splicing factor component Pex14_N PF04695.8 CDI86744.1 - 0.054 13.5 7.3 0.06 13.4 5.1 1.0 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region ERF PF04404.7 CDI86744.1 - 0.056 12.9 12.1 0.07 12.6 8.4 1.1 1 0 0 1 1 1 0 ERF superfamily Spt20 PF12090.3 CDI86744.1 - 0.064 12.6 3.9 0.064 12.5 2.7 1.1 1 0 0 1 1 1 0 Spt20 family DUF3246 PF11596.3 CDI86744.1 - 0.078 12.2 0.3 0.084 12.1 0.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) Sox_N PF12444.3 CDI86744.1 - 0.093 13.8 4.0 0.1 13.6 2.8 1.1 1 0 0 1 1 1 0 Sox developmental protein N terminal WES_acyltransf PF03007.11 CDI86744.1 - 0.098 12.1 1.6 0.11 12.0 1.1 1.0 1 0 0 1 1 1 0 Wax ester synthase-like Acyl-CoA acyltransferase domain DUF2722 PF10846.3 CDI86744.1 - 0.2 10.6 7.6 0.21 10.5 5.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) FCP1_C PF09309.5 CDI86744.1 - 0.23 10.7 6.2 0.25 10.6 4.3 1.1 1 0 0 1 1 1 0 FCP1, C-terminal DUF912 PF06024.7 CDI86744.1 - 0.24 11.4 1.3 0.26 11.3 0.9 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) SprA-related PF12118.3 CDI86744.1 - 0.25 10.6 14.7 0.26 10.5 10.2 1.0 1 0 0 1 1 1 0 SprA-related family DOR PF14839.1 CDI86744.1 - 0.26 10.9 6.4 0.29 10.8 4.5 1.1 1 0 0 1 1 1 0 DOR family Aminotran_1_2 PF00155.16 CDI86744.1 - 0.27 10.1 2.3 0.29 10.0 1.6 1.0 1 0 0 1 1 1 0 Aminotransferase class I and II DUF788 PF05620.6 CDI86744.1 - 0.34 10.7 2.3 0.39 10.5 1.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF788) DUF3464 PF11947.3 CDI86744.1 - 0.35 10.3 1.7 0.38 10.2 1.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) DUF2782 PF11191.3 CDI86744.1 - 0.38 10.7 4.2 0.48 10.4 2.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2782) G0-G1_switch_2 PF15103.1 CDI86744.1 - 0.53 10.5 4.5 0.6 10.3 3.1 1.1 1 0 0 1 1 1 0 G0/G1 switch protein 2 Conotoxin PF02950.12 CDI86744.1 - 0.6 10.9 4.7 0.79 10.5 3.2 1.2 1 0 0 1 1 1 0 Conotoxin PepSY_2 PF13670.1 CDI86744.1 - 0.74 9.7 4.8 0.94 9.4 3.3 1.1 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain Suf PF05843.9 CDI86744.1 - 0.91 9.2 6.9 0.87 9.2 4.8 1.0 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF3373 PF11853.3 CDI86744.1 - 1.3 7.5 5.9 1.3 7.4 4.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) BAF1_ABF1 PF04684.8 CDI86744.1 - 6.5 5.4 14.2 7.7 5.2 9.8 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor DUF3154 PF11351.3 CDI86744.1 - 8.9 6.0 12.9 75 3.0 8.9 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3154) VIT1 PF01988.14 CDI86745.1 - 0.0022 17.5 1.0 0.0022 17.5 0.7 3.9 4 1 0 4 4 4 1 VIT family IncA PF04156.9 CDI86745.1 - 0.024 14.2 0.7 0.024 14.2 0.5 5.4 3 2 0 3 3 3 0 IncA protein Caldesmon PF02029.10 CDI86746.1 - 1.6 7.0 14.7 2.5 6.3 10.2 1.4 1 0 0 1 1 1 0 Caldesmon Chorion_2 PF03964.10 CDI86746.1 - 7.2 7.2 36.3 1.4 9.4 3.0 3.7 2 1 1 3 3 3 0 Chorion family 2 Med15 PF09606.5 CDI86747.1 - 0.00022 19.6 36.3 0.00028 19.2 25.1 1.2 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal FimP PF09766.4 CDI86747.1 - 0.0021 17.2 16.8 0.0029 16.7 11.7 1.3 1 0 0 1 1 1 1 Fms-interacting protein Ycf1 PF05758.7 CDI86747.1 - 0.0048 14.7 4.2 0.0044 14.8 2.9 1.0 1 0 0 1 1 1 1 Ycf1 Serinc PF03348.10 CDI86747.1 - 0.05 12.3 6.8 0.076 11.7 4.7 1.4 1 0 0 1 1 1 0 Serine incorporator (Serinc) Herpes_UL87 PF03043.9 CDI86747.1 - 0.06 11.7 3.6 0.072 11.4 2.5 1.2 1 0 0 1 1 1 0 Herpesvirus UL87 family SAPS PF04499.10 CDI86747.1 - 0.12 10.9 10.8 0.15 10.7 7.5 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein SpoVR PF04293.8 CDI86747.1 - 0.14 10.4 8.8 0.17 10.1 6.1 1.1 1 0 0 1 1 1 0 SpoVR like protein PAT1 PF09770.4 CDI86747.1 - 0.18 10.0 35.0 0.24 9.5 24.3 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SeqA PF03925.8 CDI86747.1 - 0.27 10.9 7.8 0.47 10.1 5.4 1.5 1 0 0 1 1 1 0 SeqA protein Tim54 PF11711.3 CDI86747.1 - 0.4 9.2 9.1 0.61 8.6 6.3 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 OATP PF03137.15 CDI86747.1 - 0.54 8.2 5.6 0.71 7.8 3.9 1.4 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family FHIPEP PF00771.15 CDI86747.1 - 0.58 8.4 6.2 0.76 8.0 4.3 1.2 1 0 0 1 1 1 0 FHIPEP family Peptidase_S49_N PF08496.5 CDI86747.1 - 0.68 9.7 7.4 0.96 9.2 5.1 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal zf-DHHC PF01529.15 CDI86747.1 - 0.79 9.0 4.9 1.2 8.4 3.4 1.4 1 0 0 1 1 1 0 DHHC palmitoyltransferase Otopetrin PF03189.8 CDI86747.1 - 0.9 8.4 4.5 1.1 8.1 3.1 1.2 1 0 0 1 1 1 0 Otopetrin eIF-3_zeta PF05091.7 CDI86747.1 - 0.91 8.0 17.5 1.1 7.7 12.1 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) LMBR1 PF04791.11 CDI86747.1 - 0.93 7.9 5.4 1.3 7.5 3.8 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF4407 PF14362.1 CDI86747.1 - 0.98 8.3 23.1 2.7 6.8 16.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) AAT PF03417.11 CDI86747.1 - 1 8.7 9.9 1.5 8.2 6.8 1.3 1 0 0 1 1 1 0 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase Paramyxo_ncap PF00973.14 CDI86747.1 - 1.1 7.8 8.8 1.7 7.2 6.1 1.3 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein DDRGK PF09756.4 CDI86747.1 - 1.2 8.4 15.7 1.7 8.0 10.9 1.1 1 0 0 1 1 1 0 DDRGK domain U79_P34 PF03064.11 CDI86747.1 - 1.3 8.4 16.7 0.18 11.3 5.9 2.1 2 0 0 2 2 2 0 HSV U79 / HCMV P34 SelP_N PF04592.9 CDI86747.1 - 1.4 8.2 14.9 2.6 7.3 10.3 1.4 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Sec62 PF03839.11 CDI86747.1 - 1.4 8.2 6.3 1.8 7.8 4.4 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 Alpha_GJ PF03229.8 CDI86747.1 - 1.5 9.1 23.3 0.8 10.0 10.8 2.3 2 0 0 2 2 2 0 Alphavirus glycoprotein J BTV_NS2 PF04514.7 CDI86747.1 - 1.5 7.5 8.4 2.2 7.0 5.9 1.2 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 SID-1_RNA_chan PF13965.1 CDI86747.1 - 1.6 6.7 4.3 1.9 6.5 3.0 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DUF3450 PF11932.3 CDI86747.1 - 1.8 7.7 29.8 2.6 7.2 20.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF3381 PF11861.3 CDI86747.1 - 1.9 7.9 13.7 2.8 7.4 9.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) Glyco_transf_15 PF01793.11 CDI86747.1 - 2.3 7.0 10.0 3.4 6.5 7.0 1.2 1 0 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase Peptidase_U57 PF05582.7 CDI86747.1 - 2.3 7.0 8.6 3 6.7 5.9 1.1 1 0 0 1 1 1 0 YabG peptidase U57 Folate_carrier PF01770.13 CDI86747.1 - 2.4 6.5 6.1 3.4 6.0 4.2 1.3 1 0 0 1 1 1 0 Reduced folate carrier DUF3675 PF12428.3 CDI86747.1 - 2.7 8.2 13.4 0.66 10.2 6.4 2.2 2 1 0 2 2 1 0 Protein of unknown function (DUF3675) tRNA-synt_2c PF01411.14 CDI86747.1 - 3.3 5.8 9.2 4.2 5.5 6.4 1.1 1 0 0 1 1 1 0 tRNA synthetases class II (A) NARP1 PF12569.3 CDI86747.1 - 6.7 5.3 17.6 8.7 4.9 12.2 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DUF106 PF01956.11 CDI86747.1 - 8.2 5.9 8.7 11 5.4 6.0 1.2 1 0 0 1 1 1 0 Integral membrane protein DUF106 NPR3 PF03666.8 CDI86747.1 - 8.5 4.7 18.0 0.4 9.1 7.1 2.0 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 CAF-1_p150 PF11600.3 CDI86748.1 - 0.13 11.6 51.1 0.16 11.2 35.4 1.0 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal SprA-related PF12118.3 CDI86748.1 - 0.63 9.3 77.5 0.8 8.9 53.7 1.0 1 0 0 1 1 1 0 SprA-related family SR-25 PF10500.4 CDI86748.1 - 9.3 5.6 57.1 0.12 11.8 27.3 2.0 1 1 1 2 2 2 0 Nuclear RNA-splicing-associated protein Claudin_2 PF13903.1 CDI86749.1 - 0.0082 15.8 4.8 0.0082 15.8 3.3 2.7 2 1 0 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction Pex14_N PF04695.8 CDI86749.1 - 0.02 14.9 20.8 0.44 10.6 3.6 3.2 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Phostensin_N PF13916.1 CDI86749.1 - 0.12 12.3 11.1 0.35 10.8 0.1 3.1 3 0 0 3 3 3 0 PP1-regulatory protein, Phostensin N-terminal Ribosomal_60s PF00428.14 CDI86749.1 - 2.3 8.6 49.5 0.7 10.3 8.2 4.5 4 0 0 4 4 4 0 60s Acidic ribosomal protein Activator_LAG-3 PF11498.3 CDI86749.1 - 2.9 6.5 35.8 0.16 10.7 11.0 2.4 2 0 0 2 2 2 0 Transcriptional activator LAG-3 CAF-1_p150 PF11600.3 CDI86750.1 - 0.089 12.1 34.4 0.11 11.9 23.9 1.0 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal SprA-related PF12118.3 CDI86750.1 - 1.6 7.9 46.5 1.9 7.7 32.2 1.0 1 0 0 1 1 1 0 SprA-related family Tmemb_cc2 PF10267.4 CDI86750.1 - 2 6.9 28.5 2.1 6.8 19.8 1.0 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein Corona_nucleoca PF00937.13 CDI86750.1 - 5 5.9 36.2 6 5.7 25.1 1.1 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein DDRGK PF09756.4 CDI86750.1 - 6.8 6.0 20.2 7.4 5.9 14.0 1.2 1 0 0 1 1 1 0 DDRGK domain Prenyltransf PF01255.14 CDI86751.1 - 1.2e-09 37.6 2.4 1.2e-09 37.6 1.7 1.8 2 1 0 2 2 2 1 Putative undecaprenyl diphosphate synthase Sporozoite_P67 PF05642.6 CDI86751.1 - 0.032 12.1 18.7 0.047 11.5 13.0 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF2215 PF10225.4 CDI86751.1 - 0.17 11.3 14.7 0.11 11.9 4.0 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2215) DUF2052 PF09747.4 CDI86751.1 - 1.3 8.8 32.8 0.063 13.2 8.9 2.1 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) SPX PF03105.14 CDI86751.1 - 4.4 6.9 21.7 0.41 10.3 4.6 2.1 2 0 0 2 2 2 0 SPX domain DUF4045 PF13254.1 CDI86751.1 - 7.3 5.7 25.7 0.24 10.6 8.8 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4045) DUF1510 PF07423.6 CDI86751.1 - 7.5 5.8 29.2 1.5 8.1 8.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) CD20 PF04103.10 CDI86752.1 - 0.0059 16.5 5.7 0.024 14.5 0.2 2.3 2 0 0 2 2 2 1 CD20-like family IncA PF04156.9 CDI86752.1 - 0.019 14.5 29.8 0.023 14.2 7.8 2.2 2 0 0 2 2 2 0 IncA protein Shadoo PF14999.1 CDI86752.1 - 0.037 13.8 1.0 0.037 13.8 0.7 3.8 3 1 0 3 3 2 0 Shadow of prion protein, neuroprotective SR-25 PF10500.4 CDI86752.1 - 0.19 11.1 33.4 0.82 9.1 1.1 2.3 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein FAM60A PF15396.1 CDI86752.1 - 0.24 11.1 26.6 0.66 9.6 2.1 2.2 2 0 0 2 2 2 0 Protein Family FAM60A DUF966 PF06136.8 CDI86752.1 - 0.31 10.4 29.1 0.42 9.9 20.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) DUF2232 PF09991.4 CDI86752.1 - 0.46 9.4 8.5 0.11 11.5 0.3 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2232) Pal1 PF08316.6 CDI86752.1 - 0.97 9.8 20.9 1.8 9.0 2.4 2.3 2 0 0 2 2 2 0 Pal1 cell morphology protein Dapper PF15268.1 CDI86752.1 - 2.2 6.9 38.1 3 6.5 26.4 1.1 1 0 0 1 1 1 0 Dapper MARCKS PF02063.12 CDI86752.1 - 3.5 7.3 52.9 1.7 8.4 17.1 2.1 2 0 0 2 2 2 0 MARCKS family Zip PF02535.17 CDI86752.1 - 5.5 5.8 25.6 0.051 12.5 3.8 2.2 2 0 0 2 2 2 0 ZIP Zinc transporter DUF2215 PF10225.4 CDI86752.1 - 9.3 5.6 15.5 4.5 6.6 0.8 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2215) DUF2029 PF09594.5 CDI86753.1 - 0.058 12.8 12.1 0.069 12.6 8.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2029) Rifin_STEVOR PF02009.11 CDI86753.1 - 0.74 9.3 6.3 0.98 9.0 4.4 1.2 1 0 0 1 1 1 0 Rifin/stevor family DUF1772 PF08592.6 CDI86753.1 - 1.4 8.6 15.0 1 9.1 0.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1772) DUF1826 PF08856.6 CDI86753.1 - 1.6 8.4 4.5 0.81 9.4 1.8 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1826) SpaB_C PF14028.1 CDI86753.1 - 3.5 7.0 15.1 4.6 6.7 10.4 1.1 1 0 0 1 1 1 0 SpaB C-terminal domain Ferrochelatase PF00762.14 CDI86754.1 - 1.4e-31 109.6 1.9 4e-14 52.3 0.1 3.2 1 1 1 3 3 3 3 Ferrochelatase Peptidase_S49_N PF08496.5 CDI86756.1 - 0.02 14.6 6.0 0.021 14.6 4.2 1.0 1 0 0 1 1 1 0 Peptidase family S49 N-terminal RED_N PF07808.8 CDI86756.1 - 0.033 13.3 10.3 0.036 13.2 7.2 1.0 1 0 0 1 1 1 0 RED-like protein N-terminal region BRF1 PF07741.8 CDI86756.1 - 0.039 14.1 9.2 0.042 14.0 6.4 1.0 1 0 0 1 1 1 0 Brf1-like TBP-binding domain PIP5K PF01504.13 CDI86756.1 - 0.051 12.6 1.5 0.056 12.5 1.0 1.0 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase DUF3371 PF11851.3 CDI86756.1 - 0.052 14.2 8.9 0.055 14.1 6.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3371) DUF1764 PF08576.5 CDI86756.1 - 0.058 14.1 4.9 0.057 14.2 3.4 1.1 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) Suf PF05843.9 CDI86756.1 - 0.087 12.5 8.8 0.077 12.7 6.1 1.0 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF2052 PF09747.4 CDI86756.1 - 0.088 12.7 8.8 0.092 12.6 6.1 1.0 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) TOH_N PF12549.3 CDI86756.1 - 0.12 11.9 0.0 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 Tyrosine hydroxylase N terminal TMEM51 PF15345.1 CDI86756.1 - 0.17 11.5 7.9 0.19 11.4 5.5 1.0 1 0 0 1 1 1 0 Transmembrane protein 51 AIF_C PF14721.1 CDI86756.1 - 0.17 12.1 2.6 0.18 12.0 1.8 1.1 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term DUF2828 PF11443.3 CDI86756.1 - 0.26 9.4 3.4 0.25 9.4 2.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Ctr PF04145.10 CDI86756.1 - 0.33 10.9 3.4 0.36 10.8 2.4 1.1 1 0 0 1 1 1 0 Ctr copper transporter family FimP PF09766.4 CDI86756.1 - 0.35 9.9 14.5 0.34 9.9 10.0 1.0 1 0 0 1 1 1 0 Fms-interacting protein Band_3_cyto PF07565.8 CDI86756.1 - 0.42 10.0 5.0 0.41 10.1 3.5 1.0 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Folliculin PF11704.3 CDI86756.1 - 0.45 10.0 4.7 0.46 10.0 3.3 1.1 1 0 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport DUF912 PF06024.7 CDI86756.1 - 0.46 10.5 2.8 0.49 10.4 1.9 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF3994 PF13159.1 CDI86756.1 - 0.47 10.7 3.5 0.52 10.5 2.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3994) Spt20 PF12090.3 CDI86756.1 - 0.48 9.7 9.3 0.5 9.6 6.5 1.1 1 0 0 1 1 1 0 Spt20 family DUF4647 PF15504.1 CDI86756.1 - 0.53 9.0 10.5 0.55 9.0 7.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4647) Activator_LAG-3 PF11498.3 CDI86756.1 - 0.59 8.8 29.0 0.56 8.8 20.1 1.0 1 0 0 1 1 1 0 Transcriptional activator LAG-3 DUF3043 PF11241.3 CDI86756.1 - 0.6 9.6 4.9 0.6 9.6 3.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) DivIC PF04977.10 CDI86756.1 - 0.7 9.4 15.8 0.87 9.1 10.9 1.1 1 0 0 1 1 1 0 Septum formation initiator Serinc PF03348.10 CDI86756.1 - 0.82 8.3 5.7 0.81 8.3 3.9 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) Med15 PF09606.5 CDI86756.1 - 0.91 7.6 25.7 0.85 7.7 17.8 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal PAT1 PF09770.4 CDI86756.1 - 0.95 7.6 16.3 0.97 7.5 11.3 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Rpp20 PF12328.3 CDI86756.1 - 1.1 8.9 7.0 1.2 8.8 4.9 1.1 1 0 0 1 1 1 0 Rpp20 subunit of nuclear RNase MRP and P RR_TM4-6 PF06459.7 CDI86756.1 - 1.2 8.9 6.2 1.2 8.9 4.3 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF4557 PF15101.1 CDI86756.1 - 1.5 8.5 14.5 1.5 8.5 10.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) DUF4175 PF13779.1 CDI86756.1 - 1.6 6.3 21.8 1.5 6.4 15.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Conotoxin PF02950.12 CDI86756.1 - 1.6 9.5 3.8 2 9.2 2.6 1.2 1 0 0 1 1 1 0 Conotoxin DDHD PF02862.12 CDI86756.1 - 1.7 8.3 6.0 1.7 8.4 4.2 1.0 1 0 0 1 1 1 0 DDHD domain DUF3464 PF11947.3 CDI86756.1 - 1.7 8.0 4.9 1.8 7.9 3.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) RAB3GAP2_N PF14655.1 CDI86756.1 - 1.9 7.4 9.5 2.3 7.1 6.6 1.3 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus DUF4207 PF13904.1 CDI86756.1 - 2.2 7.6 20.6 2.3 7.5 14.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4207) EIIBC-GUT_N PF03612.9 CDI86756.1 - 2.3 7.8 5.0 2.5 7.6 3.5 1.1 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus DUF775 PF05603.7 CDI86756.1 - 2.5 7.5 8.1 2.8 7.4 5.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF775) FCP1_C PF09309.5 CDI86756.1 - 2.6 7.3 10.3 2.7 7.2 7.2 1.1 1 0 0 1 1 1 0 FCP1, C-terminal GvpL_GvpF PF06386.6 CDI86756.1 - 2.6 7.5 8.7 2.7 7.5 6.0 1.0 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF Pex16 PF08610.5 CDI86756.1 - 2.7 6.8 6.7 2.6 6.9 4.7 1.0 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) OmpH PF03938.9 CDI86756.1 - 3.2 7.6 19.9 3.4 7.5 13.8 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) BAF1_ABF1 PF04684.8 CDI86756.1 - 3.6 6.3 20.5 3.5 6.3 14.2 1.0 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor UPF0560 PF10577.4 CDI86756.1 - 3.7 5.6 11.3 3.9 5.6 7.9 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 G0-G1_switch_2 PF15103.1 CDI86756.1 - 4.4 7.5 8.2 5 7.4 5.7 1.1 1 0 0 1 1 1 0 G0/G1 switch protein 2 DUF1682 PF07946.9 CDI86756.1 - 4.7 5.9 12.2 5.3 5.7 8.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) DUF4407 PF14362.1 CDI86756.1 - 4.7 6.0 10.4 4.6 6.0 7.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF3154 PF11351.3 CDI86756.1 - 4.8 6.9 6.9 5.5 6.7 4.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3154) Prog_receptor PF02161.10 CDI86756.1 - 5.5 5.6 6.6 5.7 5.6 4.6 1.0 1 0 0 1 1 1 0 Progesterone receptor eIF-3_zeta PF05091.7 CDI86756.1 - 6.4 5.2 10.9 6.6 5.2 7.5 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) SR-25 PF10500.4 CDI86757.1 - 2.2e-05 24.0 104.3 2.7e-05 23.7 21.8 5.1 5 0 0 5 5 5 3 Nuclear RNA-splicing-associated protein DUF3801 PF12687.2 CDI86757.1 - 0.0018 17.8 21.0 0.0018 17.8 14.5 4.1 3 1 0 3 3 3 1 Protein of unknown function (DUF3801) Cwf_Cwc_15 PF04889.7 CDI86757.1 - 0.0052 16.5 23.6 0.0052 16.5 16.4 4.4 5 0 0 5 5 5 2 Cwf15/Cwc15 cell cycle control protein DUF4207 PF13904.1 CDI86758.1 - 0.024 14.0 24.2 0.032 13.6 16.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4207) Peptidase_M19 PF01244.16 CDI86758.1 - 0.047 12.6 3.2 0.064 12.1 2.3 1.1 1 0 0 1 1 1 0 Membrane dipeptidase (Peptidase family M19) DUF2500 PF10694.4 CDI86758.1 - 0.14 12.1 3.0 0.32 11.0 2.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2500) Glyco_transf_20 PF00982.16 CDI86758.1 - 0.3 9.5 3.0 0.47 8.8 2.1 1.3 1 0 0 1 1 1 0 Glycosyltransferase family 20 Macoilin PF09726.4 CDI86758.1 - 5.9 5.0 32.9 9.2 4.4 22.8 1.3 1 0 0 1 1 1 0 Transmembrane protein SR-25 PF10500.4 CDI86759.1 - 0.0014 18.1 5.4 0.0014 18.1 3.7 20.2 15 4 4 20 20 20 4 Nuclear RNA-splicing-associated protein MIP-T3 PF10243.4 CDI86761.1 - 0.031 12.7 47.1 0.037 12.4 32.6 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 WD40 PF00400.27 CDI86762.1 - 6.6e-16 57.4 1.2 9.2e-08 31.6 0.2 2.4 2 0 0 2 2 2 2 WD domain, G-beta repeat Apc4_WD40 PF12894.2 CDI86762.1 - 0.028 13.9 0.1 5.6 6.5 0.0 2.5 1 1 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain DUF3138 PF11336.3 CDI86762.1 - 1.5 6.8 7.3 1.9 6.6 5.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) MIP-T3 PF10243.4 CDI86763.1 - 6.4 5.1 91.6 3.2 6.0 7.8 2.2 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 AP2 PF00847.15 CDI86764.1 - 7.2e-06 26.0 0.2 1.8e-05 24.8 0.1 1.7 1 0 0 1 1 1 1 AP2 domain C2 PF00168.25 CDI86765.1 - 4e-27 93.8 0.1 3.1e-07 30.1 0.0 6.4 6 1 0 6 6 6 5 C2 domain Pyr_redox_dim PF02852.17 CDI86766.1 - 3.9e-35 120.1 0.0 8.9e-35 119.0 0.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox_2 PF07992.9 CDI86766.1 - 2.7e-34 118.8 0.0 1e-33 116.9 0.0 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 CDI86766.1 - 9.1e-22 77.2 9.5 4.7e-19 68.5 0.3 3.6 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 CDI86766.1 - 1.8e-11 43.7 1.9 1.3e-10 40.9 0.7 2.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 CDI86766.1 - 1e-06 27.8 2.7 1e-06 27.8 1.9 2.5 2 1 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.1 CDI86766.1 - 1.4e-06 28.1 3.7 0.00019 21.3 0.2 3.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 CDI86766.1 - 1.6e-06 28.3 2.6 0.0036 17.3 1.6 3.4 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 CDI86766.1 - 2.5e-05 23.4 0.7 6.8e-05 22.0 0.0 2.0 2 0 0 2 2 2 1 Thi4 family DAO PF01266.19 CDI86766.1 - 7.4e-05 21.8 11.3 0.022 13.7 0.3 4.5 4 0 0 4 4 4 2 FAD dependent oxidoreductase GIDA PF01134.17 CDI86766.1 - 7.9e-05 21.6 8.2 0.0027 16.6 2.1 3.1 2 1 1 3 3 3 2 Glucose inhibited division protein A K_oxygenase PF13434.1 CDI86766.1 - 0.00011 21.2 2.6 0.015 14.2 0.0 2.6 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_3 PF01494.14 CDI86766.1 - 0.00016 20.8 6.1 0.31 10.0 0.5 3.4 3 0 0 3 3 3 3 FAD binding domain HI0933_like PF03486.9 CDI86766.1 - 0.0046 15.4 1.0 0.0046 15.4 0.7 4.4 4 1 1 5 5 5 1 HI0933-like protein Adaptin_binding PF10199.4 CDI86766.1 - 0.0092 16.2 1.6 0.018 15.2 1.1 1.4 1 0 0 1 1 1 1 Alpha and gamma adaptin binding protein p34 HOOK PF05622.7 CDI86766.1 - 0.019 12.7 9.9 0.028 12.2 6.8 1.1 1 0 0 1 1 1 0 HOOK protein 3HCDH_N PF02737.13 CDI86766.1 - 0.039 13.6 0.1 0.039 13.6 0.1 2.8 3 0 0 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TBPIP PF07106.8 CDI86766.1 - 0.23 10.9 5.9 0.4 10.2 4.1 1.3 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) AlaDh_PNT_C PF01262.16 CDI86766.1 - 0.55 9.7 3.5 1.1 8.7 0.1 2.7 3 0 0 3 3 3 0 Alanine dehydrogenase/PNT, C-terminal domain ERM PF00769.14 CDI86766.1 - 0.58 9.6 13.7 1 8.8 9.5 1.3 1 0 0 1 1 1 0 Ezrin/radixin/moesin family Abhydrolase_5 PF12695.2 CDI86767.1 - 6.2e-11 42.2 0.0 8.1e-11 41.8 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CDI86767.1 - 1.3e-05 25.1 0.0 0.0077 16.1 0.0 2.3 1 1 1 2 2 2 2 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 CDI86767.1 - 0.00045 19.4 0.0 0.21 10.7 0.0 2.1 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_3 PF07859.8 CDI86767.1 - 0.009 15.6 0.0 0.0098 15.4 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 CDI86767.1 - 0.15 10.6 0.0 0.21 10.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2424) Peptidase_S9_N PF02897.10 CDI86768.1 - 8.3e-104 347.4 0.1 1e-103 347.1 0.0 1.1 1 0 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Peptidase_S9 PF00326.16 CDI86768.1 - 2.2e-47 161.0 0.0 4.4e-47 160.0 0.0 1.6 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 CDI86768.1 - 0.023 14.4 0.0 0.044 13.5 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family AXE1 PF05448.7 CDI86768.1 - 0.036 12.5 0.0 0.064 11.7 0.0 1.3 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Biotin_lipoyl PF00364.17 CDI86771.1 - 1.9e-16 59.4 0.2 2.9e-16 58.8 0.1 1.3 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.1 CDI86771.1 - 2.4e-05 23.9 0.3 6.9e-05 22.4 0.2 2.0 1 1 0 1 1 1 1 Biotin-lipoyl like HlyD_2 PF12700.2 CDI86771.1 - 0.08 12.0 0.3 0.23 10.5 0.2 1.6 1 1 0 1 1 1 0 HlyD family secretion protein PRCH PF03967.8 CDI86771.1 - 0.34 10.4 2.5 0.56 9.8 1.7 1.3 1 0 0 1 1 1 0 Photosynthetic reaction centre, H-chain N-terminal region Peptidase_S49_N PF08496.5 CDI86773.1 - 0.64 9.7 24.3 0.78 9.5 16.9 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal NST1 PF13945.1 CDI86773.1 - 3.8 7.5 28.8 4.6 7.2 19.9 1.1 1 0 0 1 1 1 0 Salt tolerance down-regulator NARP1 PF12569.3 CDI86773.1 - 4 6.0 25.9 4 6.0 18.0 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 FYDLN_acid PF09538.5 CDI86773.1 - 6.4 7.4 12.7 8.4 7.0 8.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) DDRGK PF09756.4 CDI86773.1 - 8.5 5.7 34.9 9 5.6 24.2 1.1 1 0 0 1 1 1 0 DDRGK domain RRM_1 PF00076.17 CDI86774.1 - 3.9e-09 36.0 0.0 6.4e-09 35.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CDI86774.1 - 2.5e-08 33.7 0.0 4.7e-08 32.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 CDI86774.1 - 0.00041 20.0 0.0 0.0021 17.7 0.0 1.9 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.1 CDI86774.1 - 0.01 15.6 0.0 0.021 14.6 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNA_pol_Rpb4 PF03874.11 CDI86774.1 - 0.079 12.9 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 RNA polymerase Rpb4 DnaJ PF00226.26 CDI86776.1 - 2.6e-25 87.9 1.5 4.6e-25 87.1 1.1 1.4 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 CDI86776.1 - 8e-10 38.4 0.0 2.1e-09 37.1 0.0 1.6 1 0 0 1 1 1 1 DnaJ C terminal domain DUF106 PF01956.11 CDI86777.1 - 0.0013 18.2 0.0 0.0013 18.2 0.0 10.3 4 2 2 6 6 6 1 Integral membrane protein DUF106 Presenilin PF01080.12 CDI86778.1 - 0.15 10.8 6.1 0.21 10.3 4.2 1.2 1 0 0 1 1 1 0 Presenilin DUF853 PF05872.7 CDI86778.1 - 0.31 9.3 11.7 0.46 8.7 8.1 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) Hid1 PF12722.2 CDI86778.1 - 3.3 5.2 12.5 4 5.0 8.7 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF740 PF05340.7 CDI86779.1 - 0.23 9.8 7.3 0.26 9.5 5.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF740) Nha1_C PF08619.5 CDI86779.1 - 1 8.5 17.4 1.1 8.5 12.0 1.0 1 0 0 1 1 1 0 Alkali metal cation/H+ antiporter Nha1 C terminus DUF778 PF05608.7 CDI86779.1 - 1.3 8.9 7.0 1.5 8.7 4.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF778) Rtf2 PF04641.7 CDI86779.1 - 2.1 7.4 18.9 2.2 7.4 13.1 1.0 1 0 0 1 1 1 0 Rtf2 RING-finger FAM176 PF14851.1 CDI86779.1 - 2.8 7.6 10.1 3.8 7.1 7.0 1.3 1 0 0 1 1 1 0 FAM176 family AIF_C PF14721.1 CDI86779.1 - 4.1 7.6 15.3 5.2 7.3 10.6 1.1 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term FYDLN_acid PF09538.5 CDI86779.1 - 4.1 8.0 8.3 5.1 7.7 5.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) Pex14_N PF04695.8 CDI86779.1 - 4.1 7.4 26.6 5.3 7.0 18.5 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF1764 PF08576.5 CDI86779.1 - 5.4 7.8 19.4 8 7.2 13.4 1.3 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) Spore_coat_CotO PF14153.1 CDI86779.1 - 6 6.2 27.8 6.6 6.1 19.3 1.0 1 0 0 1 1 1 0 Spore coat protein CotO DUF89 PF01937.14 CDI86779.1 - 6.8 5.3 11.2 7 5.3 7.8 1.0 1 0 0 1 1 1 0 Protein of unknown function DUF89 ARD PF03079.9 CDI86779.1 - 7.2 6.5 13.5 7.5 6.4 9.3 1.0 1 0 0 1 1 1 0 ARD/ARD' family DUF2058 PF09831.4 CDI86779.1 - 7.3 6.4 30.1 7.8 6.3 20.9 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2058) BORG_CEP PF14957.1 CDI86779.1 - 8.2 7.3 12.0 9.4 7.1 8.3 1.1 1 0 0 1 1 1 0 Cdc42 effector HCO3_cotransp PF00955.16 CDI86779.1 - 8.6 4.8 8.9 8.5 4.9 6.2 1.0 1 0 0 1 1 1 0 HCO3- transporter family FLO_LFY PF01698.11 CDI86779.1 - 8.8 5.0 17.6 9.2 4.9 12.2 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein NPR3 PF03666.8 CDI86779.1 - 9.5 4.6 18.3 11 4.4 12.7 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 CDK2AP PF09806.4 CDI86780.1 - 0.0003 21.1 13.2 0.00041 20.6 9.2 1.1 1 0 0 1 1 1 1 Cyclin-dependent kinase 2-associated protein TFIIA PF03153.8 CDI86780.1 - 0.22 11.4 18.9 0.27 11.1 13.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PHD_3 PF13922.1 CDI86780.1 - 0.93 9.7 12.6 2.5 8.4 3.6 2.5 2 0 0 2 2 2 0 PHD domain of transcriptional enhancer, Asx PLRV_ORF5 PF01690.12 CDI86780.1 - 3.3 6.7 10.0 3.6 6.6 6.9 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein RAB3GAP2_N PF14655.1 CDI86780.1 - 3.4 6.5 13.2 3.7 6.4 0.6 2.1 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus FYDLN_acid PF09538.5 CDI86780.1 - 3.9 8.0 9.3 8.1 7.0 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) Ribosomal_60s PF00428.14 CDI86780.1 - 8.8 6.8 18.4 0.17 12.2 3.2 2.7 3 0 0 3 3 3 0 60s Acidic ribosomal protein DUF4551 PF15087.1 CDI86780.1 - 9.9 4.3 8.5 13 3.9 5.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) SR-25 PF10500.4 CDI86781.1 - 2.7 7.4 82.6 6.2 6.2 14.3 2.2 1 1 1 2 2 2 0 Nuclear RNA-splicing-associated protein CAF-1_p150 PF11600.3 CDI86782.1 - 0.06 12.7 19.9 0.17 11.2 13.8 1.7 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Med15 PF09606.5 CDI86783.1 - 4.6e-05 21.8 83.5 5.4e-05 21.6 57.9 1.0 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal PAT1 PF09770.4 CDI86783.1 - 0.0025 16.1 76.7 0.0028 16.0 53.2 1.0 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 MIP-T3 PF10243.4 CDI86783.1 - 0.014 13.9 45.3 0.016 13.6 31.4 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 SOBP PF15279.1 CDI86783.1 - 0.26 11.6 34.4 0.33 11.2 23.8 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein Daxx PF03344.10 CDI86783.1 - 0.91 7.9 40.1 1.2 7.5 27.8 1.1 1 0 0 1 1 1 0 Daxx Family MRP-S27 PF10037.4 CDI86783.1 - 2.1 7.1 28.6 2.4 6.9 19.9 1.0 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S27 DUF2413 PF10310.4 CDI86783.1 - 6.9 5.3 44.6 9.6 4.8 30.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) TFIIA PF03153.8 CDI86783.1 - 8.4 6.1 59.6 13 5.5 41.3 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF515 PF04415.7 CDI86785.1 - 2 6.5 10.3 3 5.9 7.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF515) RAP1 PF07218.6 CDI86785.1 - 8.8 4.2 15.5 12 3.7 10.7 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) BUD22 PF09073.5 CDI86786.1 - 0.081 11.9 19.6 0.096 11.7 13.6 1.0 1 0 0 1 1 1 0 BUD22 CENP-T PF15511.1 CDI86786.1 - 0.15 11.2 15.4 0.16 11.1 10.7 1.0 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T KBP_C PF12309.3 CDI86786.1 - 0.19 10.6 5.3 0.25 10.2 3.7 1.2 1 0 0 1 1 1 0 KIF-1 binding protein C terminal CobT PF06213.7 CDI86786.1 - 0.28 10.2 25.6 0.32 10.0 17.7 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT TRAP_alpha PF03896.11 CDI86786.1 - 0.31 10.0 14.2 0.36 9.7 9.8 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DDHD PF02862.12 CDI86786.1 - 0.32 10.7 7.2 0.34 10.6 5.0 1.0 1 0 0 1 1 1 0 DDHD domain DUF3987 PF13148.1 CDI86786.1 - 0.35 9.3 8.6 0.38 9.2 6.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) DUF2413 PF10310.4 CDI86786.1 - 0.36 9.5 9.6 0.38 9.5 6.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) YqfQ PF14181.1 CDI86786.1 - 0.57 10.1 14.6 0.69 9.9 10.1 1.1 1 0 0 1 1 1 0 YqfQ-like protein Peptidase_S30 PF01577.11 CDI86786.1 - 0.57 9.5 2.9 0.68 9.2 2.0 1.0 1 0 0 1 1 1 0 Potyvirus P1 protease RNA_polI_A34 PF08208.6 CDI86786.1 - 0.96 9.0 17.4 1 8.9 12.0 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 HSP90 PF00183.13 CDI86786.1 - 0.97 7.7 21.7 1.1 7.5 15.0 1.0 1 0 0 1 1 1 0 Hsp90 protein DUF1510 PF07423.6 CDI86786.1 - 1 8.6 22.6 1.2 8.4 15.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Zip PF02535.17 CDI86786.1 - 1.1 8.1 5.8 1.1 8.1 4.0 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter AIF_C PF14721.1 CDI86786.1 - 1.2 9.3 3.9 1.3 9.2 2.7 1.1 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term DUF4175 PF13779.1 CDI86786.1 - 1.3 6.5 9.1 1.5 6.4 6.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Raftlin PF15250.1 CDI86786.1 - 2.9 6.3 7.5 2.9 6.2 5.2 1.0 1 0 0 1 1 1 0 Raftlin CDC45 PF02724.9 CDI86786.1 - 2.9 5.7 19.7 3.4 5.5 13.7 1.0 1 0 0 1 1 1 0 CDC45-like protein Paf1 PF03985.8 CDI86786.1 - 3.1 6.4 27.2 3.5 6.2 18.9 1.0 1 0 0 1 1 1 0 Paf1 DUF2052 PF09747.4 CDI86786.1 - 3.3 7.6 22.1 4.1 7.3 15.3 1.1 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) Prog_receptor PF02161.10 CDI86786.1 - 5.1 5.7 13.0 6 5.5 9.0 1.1 1 0 0 1 1 1 0 Progesterone receptor NARP1 PF12569.3 CDI86786.1 - 5.3 5.6 9.5 5.8 5.5 6.6 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DUF2457 PF10446.4 CDI86786.1 - 5.9 5.5 24.9 7.6 5.1 17.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Tim54 PF11711.3 CDI86786.1 - 7.1 5.1 12.0 7.4 5.0 8.3 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 RR_TM4-6 PF06459.7 CDI86786.1 - 7.1 6.4 17.8 8.1 6.2 12.3 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 eIF-3c_N PF05470.7 CDI86786.1 - 7.8 4.4 13.0 8.2 4.3 9.0 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus GLTSCR1 PF15249.1 CDI86787.1 - 0.64 10.1 0.0 0.64 10.1 0.0 3.3 3 0 0 3 3 3 0 Glioma tumor suppressor candidate region BAF1_ABF1 PF04684.8 CDI86788.1 - 0.0008 18.3 16.6 0.0008 18.3 11.5 4.2 3 1 1 4 4 4 1 BAF1 / ABF1 chromatin reorganising factor DDHD PF02862.12 CDI86788.1 - 0.098 12.4 16.7 0.067 12.9 5.0 2.4 2 0 0 2 2 2 0 DDHD domain HlyD_2 PF12700.2 CDI86788.1 - 0.28 10.3 9.0 0.48 9.5 6.3 1.3 1 0 0 1 1 1 0 HlyD family secretion protein WASH-7_C PF14746.1 CDI86788.1 - 0.59 9.7 12.9 0.035 13.6 1.9 2.3 2 0 0 2 2 2 0 WASH complex subunit 7, C-terminal DUF912 PF06024.7 CDI86788.1 - 1.9 8.5 10.5 36 4.4 0.3 3.5 3 0 0 3 3 3 0 Nucleopolyhedrovirus protein of unknown function (DUF912) RED_N PF07808.8 CDI86788.1 - 9.3 5.3 21.1 1 8.5 0.5 2.5 2 0 0 2 2 2 0 RED-like protein N-terminal region Med15 PF09606.5 CDI86789.1 - 0.00082 17.7 24.3 0.00098 17.4 16.9 1.0 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal Ctr PF04145.10 CDI86789.1 - 0.02 14.9 3.5 0.02 14.9 2.5 2.0 1 1 1 2 2 2 0 Ctr copper transporter family RAB3GAP2_N PF14655.1 CDI86789.1 - 0.021 13.8 5.3 0.021 13.8 3.7 1.2 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus BTV_NS2 PF04514.7 CDI86789.1 - 0.044 12.6 6.0 0.055 12.3 4.1 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Hex_IIIa PF02455.11 CDI86789.1 - 0.29 9.7 11.7 0.35 9.5 8.1 1.1 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) LIM_bind PF01803.11 CDI86789.1 - 0.65 9.0 5.2 39 3.2 0.0 2.0 2 0 0 2 2 2 0 LIM-domain binding protein Ycf1 PF05758.7 CDI86789.1 - 0.71 7.5 4.9 0.76 7.4 3.4 1.1 1 0 0 1 1 1 0 Ycf1 Serinc PF03348.10 CDI86789.1 - 0.75 8.4 5.0 0.94 8.1 3.5 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) DUF2407_C PF13373.1 CDI86789.1 - 0.78 9.6 5.1 1.2 9.0 3.5 1.3 1 0 0 1 1 1 0 DUF2407 C-terminal domain Suf PF05843.9 CDI86789.1 - 1.2 8.8 6.4 1.5 8.4 4.4 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) SelP_N PF04592.9 CDI86789.1 - 1.4 8.2 7.4 0.13 11.6 1.4 1.8 2 0 0 2 2 2 0 Selenoprotein P, N terminal region FimP PF09766.4 CDI86789.1 - 1.9 7.4 12.3 2.5 7.0 8.6 1.2 1 0 0 1 1 1 0 Fms-interacting protein Hid1 PF12722.2 CDI86789.1 - 2.1 5.9 5.4 2.2 5.8 3.7 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF1675 PF07897.6 CDI86789.1 - 2.7 7.7 8.3 0.46 10.2 3.4 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1675) Tom22 PF04281.8 CDI86789.1 - 2.9 7.4 13.1 6.3 6.3 9.1 1.5 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 DUF2347 PF09804.4 CDI86789.1 - 3.1 6.9 6.0 4.8 6.3 4.2 1.4 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2347) DUF1049 PF06305.6 CDI86789.1 - 3.4 7.2 8.7 4.8e+02 0.3 6.0 2.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1049) AlaDh_PNT_C PF01262.16 CDI86789.1 - 4.6 6.7 8.5 9.7 5.7 5.9 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Bud13 PF09736.4 CDI86789.1 - 5.2 7.3 16.1 1.8 8.7 9.4 1.5 2 0 0 2 2 2 0 Pre-mRNA-splicing factor of RES complex RE_TdeIII PF09520.5 CDI86789.1 - 6.9 5.9 8.9 11 5.2 6.1 1.3 1 0 0 1 1 1 0 Type II restriction endonuclease, TdeIII Sporozoite_P67 PF05642.6 CDI86789.1 - 7.6 4.2 13.7 0.79 7.5 6.3 1.5 1 1 0 2 2 2 0 Sporozoite P67 surface antigen FLO_LFY PF01698.11 CDI86789.1 - 9.1 5.0 17.2 6.2 5.5 11.0 1.4 1 1 0 1 1 1 0 Floricaula / Leafy protein DUF2232 PF09991.4 CDI86790.1 - 0.18 10.7 3.1 0.86 8.5 0.0 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2232) SpaB_C PF14028.1 CDI86790.1 - 0.39 10.2 21.1 2.4 7.6 14.6 1.9 1 1 0 1 1 1 0 SpaB C-terminal domain DUF4207 PF13904.1 CDI86790.1 - 1.3 8.3 40.0 0.019 14.3 2.9 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4207) Herpes_DNAp_acc PF04929.7 CDI86790.1 - 1.3 7.8 30.5 0.69 8.8 7.1 2.2 2 0 0 2 2 2 0 Herpes DNA replication accessory factor DUF972 PF06156.8 CDI86790.1 - 5.4 7.4 16.5 15 5.9 0.4 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF972) DUF3373 PF11853.3 CDI86790.1 - 6.9 5.0 11.0 0.34 9.3 0.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3373) Claudin_2 PF13903.1 CDI86791.1 - 0.18 11.4 5.8 0.19 11.4 4.0 1.0 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction RAB3GAP2_N PF14655.1 CDI86791.1 - 6.4 5.6 10.4 7.2 5.4 7.2 1.0 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Ribosomal_60s PF00428.14 CDI86792.1 - 0.042 14.2 44.3 0.066 13.6 4.2 3.9 4 0 0 4 4 4 0 60s Acidic ribosomal protein Med15 PF09606.5 CDI86792.1 - 0.77 7.8 40.4 1.2 7.2 28.0 1.3 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Macoilin PF09726.4 CDI86793.1 - 0.00061 18.2 12.1 0.00061 18.2 8.4 4.8 4 1 0 5 5 5 1 Transmembrane protein Peptidase_S15 PF02129.13 CDI86794.1 - 0.0022 17.4 10.0 0.0022 17.4 7.0 2.8 1 1 1 3 3 3 1 X-Pro dipeptidyl-peptidase (S15 family) DUF4199 PF13858.1 CDI86794.1 - 0.14 12.1 1.3 0.37 10.7 0.9 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) Suf PF05843.9 CDI86794.1 - 0.24 11.0 21.6 0.042 13.5 6.8 2.3 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) Na_trans_assoc PF06512.8 CDI86794.1 - 0.35 10.8 12.9 0.066 13.1 1.4 2.2 2 0 0 2 2 2 0 Sodium ion transport-associated DUF1183 PF06682.7 CDI86794.1 - 1.4 8.4 29.9 0.077 12.5 10.5 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF1183) Activator_LAG-3 PF11498.3 CDI86794.1 - 1.7 7.3 43.5 0.023 13.4 19.3 2.7 3 0 0 3 3 3 0 Transcriptional activator LAG-3 CDC45 PF02724.9 CDI86794.1 - 2.3 6.1 14.9 0.29 9.1 1.5 2.1 2 0 0 2 2 2 0 CDC45-like protein DUF912 PF06024.7 CDI86794.1 - 5.8 7.0 6.6 1.2 9.2 1.3 2.1 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF2215 PF10225.4 CDI86794.1 - 7.8 5.8 10.8 0.87 8.9 1.8 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2215) FimP PF09766.4 CDI86794.1 - 8.2 5.3 23.2 0.087 11.8 7.4 2.3 2 1 0 2 2 2 0 Fms-interacting protein DUF2207 PF09972.4 CDI86796.1 - 0.11 10.9 0.1 0.21 10.1 0.0 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF4175 PF13779.1 CDI86796.1 - 6.9 4.2 26.1 0.042 11.5 12.4 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4175) FHIPEP PF00771.15 CDI86797.1 - 0.0025 16.2 7.1 0.0027 16.0 4.9 1.0 1 0 0 1 1 1 1 FHIPEP family U79_P34 PF03064.11 CDI86797.1 - 0.042 13.3 9.2 0.047 13.1 6.3 1.0 1 0 0 1 1 1 0 HSV U79 / HCMV P34 VIT1 PF01988.14 CDI86797.1 - 0.06 12.8 3.3 0.075 12.5 2.3 1.1 1 0 0 1 1 1 0 VIT family FimP PF09766.4 CDI86797.1 - 0.075 12.0 22.1 0.08 12.0 15.3 1.0 1 0 0 1 1 1 0 Fms-interacting protein CD20 PF04103.10 CDI86797.1 - 0.11 12.4 0.3 0.13 12.2 0.2 1.1 1 0 0 1 1 1 0 CD20-like family DUF4175 PF13779.1 CDI86797.1 - 0.11 10.1 26.1 0.12 10.0 18.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) AIF_C PF14721.1 CDI86797.1 - 0.12 12.6 12.2 0.13 12.5 8.5 1.1 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Med15 PF09606.5 CDI86797.1 - 0.23 9.6 35.6 0.24 9.5 24.7 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal MelC1 PF06236.6 CDI86797.1 - 0.24 11.4 13.2 0.3 11.0 9.2 1.3 1 0 0 1 1 1 0 Tyrosinase co-factor MelC1 Serinc PF03348.10 CDI86797.1 - 0.25 10.0 14.2 0.29 9.8 9.8 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) DUF2232 PF09991.4 CDI86797.1 - 0.3 10.0 3.0 0.32 9.9 2.1 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) Ctr PF04145.10 CDI86797.1 - 0.31 11.0 6.4 0.35 10.8 4.4 1.1 1 0 0 1 1 1 0 Ctr copper transporter family Claudin_2 PF13903.1 CDI86797.1 - 0.32 10.6 2.3 0.45 10.1 1.6 1.3 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction zf-DHHC PF01529.15 CDI86797.1 - 0.4 10.0 5.5 0.39 10.0 3.8 1.1 1 0 0 1 1 1 0 DHHC palmitoyltransferase DUF3381 PF11861.3 CDI86797.1 - 0.4 10.1 16.2 0.44 10.0 11.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) DUF3408 PF11888.3 CDI86797.1 - 0.42 10.5 11.8 0.44 10.4 8.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) DUF3682 PF12446.3 CDI86797.1 - 0.42 10.9 23.7 0.53 10.5 16.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) OATP PF03137.15 CDI86797.1 - 0.43 8.5 6.6 0.43 8.5 4.6 1.0 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Spt20 PF12090.3 CDI86797.1 - 0.49 9.7 17.4 0.57 9.5 12.1 1.2 1 0 0 1 1 1 0 Spt20 family Virul_fac_BrkB PF03631.10 CDI86797.1 - 0.5 9.6 2.5 0.51 9.6 1.8 1.0 1 0 0 1 1 1 0 Virulence factor BrkB Rrn6 PF10214.4 CDI86797.1 - 0.58 8.1 14.7 0.53 8.3 10.2 1.0 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Bac_luciferase PF00296.15 CDI86797.1 - 0.63 9.1 8.2 0.76 8.8 5.7 1.1 1 0 0 1 1 1 0 Luciferase-like monooxygenase OPT PF03169.10 CDI86797.1 - 0.66 8.3 2.9 0.71 8.2 2.0 1.0 1 0 0 1 1 1 0 OPT oligopeptide transporter protein Oleosin PF01277.12 CDI86797.1 - 0.8 9.2 5.3 1 8.9 3.7 1.3 1 0 0 1 1 1 0 Oleosin Gag_spuma PF03276.9 CDI86797.1 - 0.83 7.9 21.6 0.89 7.8 15.0 1.1 1 0 0 1 1 1 0 Spumavirus gag protein HSP90 PF00183.13 CDI86797.1 - 0.95 7.7 10.5 1.1 7.5 7.3 1.0 1 0 0 1 1 1 0 Hsp90 protein Med19 PF10278.4 CDI86797.1 - 0.97 9.0 15.7 1.1 8.8 10.9 1.1 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 R_equi_Vir PF05526.6 CDI86797.1 - 1 8.9 12.0 1 8.9 8.3 1.1 1 0 0 1 1 1 0 Rhodococcus equi virulence-associated protein FAM222A PF15258.1 CDI86797.1 - 1 8.5 20.6 0.99 8.5 14.3 1.0 1 0 0 1 1 1 0 Protein family of FAM222A DUF3450 PF11932.3 CDI86797.1 - 1.1 8.4 25.6 1.3 8.2 17.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF2215 PF10225.4 CDI86797.1 - 1.1 8.6 4.6 1.2 8.5 3.2 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) CoA_transf_3 PF02515.12 CDI86797.1 - 1.2 8.2 8.4 1.3 8.2 5.8 1.1 1 0 0 1 1 1 0 CoA-transferase family III DDHD PF02862.12 CDI86797.1 - 1.4 8.6 14.0 1.3 8.7 9.7 1.0 1 0 0 1 1 1 0 DDHD domain FLO_LFY PF01698.11 CDI86797.1 - 1.6 7.5 14.8 1.7 7.3 10.3 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein DUF4259 PF14078.1 CDI86797.1 - 1.8 9.0 6.8 2.4 8.6 4.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4259) Pex14_N PF04695.8 CDI86797.1 - 1.9 8.5 20.2 2.3 8.2 14.0 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF1980 PF09323.5 CDI86797.1 - 2 8.1 11.4 2.1 8.0 7.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) Spore_coat_CotO PF14153.1 CDI86797.1 - 2.1 7.7 20.6 2 7.8 14.3 1.1 1 0 0 1 1 1 0 Spore coat protein CotO CDC45 PF02724.9 CDI86797.1 - 2.1 6.2 12.8 2.1 6.2 8.9 1.0 1 0 0 1 1 1 0 CDC45-like protein Ycf1 PF05758.7 CDI86797.1 - 2.2 5.8 14.1 2.1 5.9 9.8 1.0 1 0 0 1 1 1 0 Ycf1 Pal1 PF08316.6 CDI86797.1 - 2.5 8.5 13.4 3 8.3 9.3 1.0 1 0 0 1 1 1 0 Pal1 cell morphology protein DUF1764 PF08576.5 CDI86797.1 - 2.5 8.9 17.4 3 8.6 12.1 1.3 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) DUF2992 PF11208.3 CDI86797.1 - 2.7 7.9 25.2 3.1 7.6 17.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2992) DUF3373 PF11853.3 CDI86797.1 - 2.7 6.4 17.9 2.9 6.3 12.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) Fungal_trans_2 PF11951.3 CDI86797.1 - 2.8 6.4 6.6 2.5 6.5 4.6 1.0 1 0 0 1 1 1 0 Fungal specific transcription factor domain Hid1 PF12722.2 CDI86797.1 - 2.8 5.5 12.4 2.4 5.7 8.6 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein EPL1 PF10513.4 CDI86797.1 - 2.8 8.1 13.4 2.9 8.1 9.3 1.1 1 0 0 1 1 1 0 Enhancer of polycomb-like DUF607 PF04678.8 CDI86797.1 - 2.9 7.7 9.8 3.1 7.6 6.8 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF607 Tim54 PF11711.3 CDI86797.1 - 3.3 6.2 15.5 3.4 6.1 10.8 1.0 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Zip PF02535.17 CDI86797.1 - 3.5 6.5 5.6 3.5 6.5 3.9 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter TRAUB PF08164.7 CDI86797.1 - 3.5 7.7 15.3 5 7.2 10.3 1.5 1 1 1 2 2 2 0 Apoptosis-antagonizing transcription factor, C-terminal CPSF100_C PF13299.1 CDI86797.1 - 4 7.6 11.5 4.1 7.5 8.0 1.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Paf1 PF03985.8 CDI86797.1 - 4 6.0 16.1 4.1 6.0 11.2 1.0 1 0 0 1 1 1 0 Paf1 OmpH PF03938.9 CDI86797.1 - 4.1 7.3 33.0 5.1 7.0 22.9 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Dala_Dala_lig_N PF01820.16 CDI86797.1 - 4.2 7.6 8.3 5 7.4 5.7 1.2 1 0 0 1 1 1 0 D-ala D-ala ligase N-terminus DUF3371 PF11851.3 CDI86797.1 - 4.3 8.0 15.3 4.8 7.8 10.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3371) Peptidase_S49_N PF08496.5 CDI86797.1 - 4.3 7.0 14.9 5.5 6.7 10.3 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal FPN1 PF06963.7 CDI86797.1 - 4.5 5.5 5.6 4.7 5.4 3.9 1.1 1 0 0 1 1 1 0 Ferroportin1 (FPN1) Band_3_cyto PF07565.8 CDI86797.1 - 4.6 6.6 14.2 5.1 6.5 9.9 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain PBP1_TM PF14812.1 CDI86797.1 - 4.9 7.5 9.8 5.9 7.2 6.8 1.1 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal RNase_H2-Ydr279 PF09468.5 CDI86797.1 - 6.5 5.8 14.0 6.8 5.7 9.7 1.0 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) DUF4557 PF15101.1 CDI86797.1 - 6.6 6.5 24.4 7.2 6.3 16.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) Hamartin PF04388.7 CDI86797.1 - 7.2 5.1 14.2 7.8 5.0 9.8 1.0 1 0 0 1 1 1 0 Hamartin protein RIC3 PF15361.1 CDI86797.1 - 7.8 6.7 14.9 8.5 6.5 10.3 1.2 1 0 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 Cellulose_synt PF03552.9 CDI86797.1 - 7.9 4.6 7.4 7.7 4.6 5.1 1.0 1 0 0 1 1 1 0 Cellulose synthase Sec62 PF03839.11 CDI86797.1 - 8 5.8 12.5 8.5 5.7 8.7 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 Herpes_DNAp_acc PF04929.7 CDI86797.1 - 8.4 5.2 15.9 9.4 5.0 11.0 1.0 1 0 0 1 1 1 0 Herpes DNA replication accessory factor SID-1_RNA_chan PF13965.1 CDI86797.1 - 9 4.3 7.5 8.6 4.3 5.2 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Suf PF05843.9 CDI86797.1 - 9 5.9 19.4 8.9 5.9 13.4 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) FimP PF09766.4 CDI86799.1 - 0.3 10.1 19.1 0.47 9.4 13.2 1.2 1 0 0 1 1 1 0 Fms-interacting protein PEX11 PF05648.9 CDI86799.1 - 1 8.5 4.0 2.4 7.3 2.8 1.6 1 0 0 1 1 1 0 Peroxisomal biogenesis factor 11 (PEX11) AAA_23 PF13476.1 CDI86799.1 - 6.7 6.9 15.8 9.8 6.4 10.9 1.2 1 0 0 1 1 1 0 AAA domain Ycf1 PF05758.7 CDI86799.1 - 9.1 3.8 13.3 12 3.4 9.2 1.1 1 0 0 1 1 1 0 Ycf1 Peptidase_C6 PF00851.13 CDI86799.1 - 9.7 4.6 10.8 14 4.1 7.5 1.2 1 0 0 1 1 1 0 Helper component proteinase Raftlin PF15250.1 CDI86799.1 - 10 4.5 14.8 0.44 9.0 6.0 1.7 2 1 0 2 2 2 0 Raftlin IncA PF04156.9 CDI86801.1 - 4e-05 23.2 22.4 4e-05 23.2 15.5 2.3 2 1 1 3 3 1 1 IncA protein HemX PF04375.9 CDI86801.1 - 0.0013 17.4 32.7 0.0013 17.4 22.7 2.0 2 0 0 2 2 1 1 HemX DDHD PF02862.12 CDI86801.1 - 0.0042 16.9 10.6 0.0049 16.7 7.3 1.1 1 0 0 1 1 1 1 DDHD domain Med15 PF09606.5 CDI86801.1 - 0.0062 14.7 61.3 0.01 14.0 42.5 1.3 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal Herpes_DNAp_acc PF04929.7 CDI86801.1 - 0.011 14.7 4.7 0.012 14.6 3.3 1.2 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Mem_trans PF03547.13 CDI86801.1 - 0.021 13.1 6.1 0.034 12.4 4.3 1.4 1 0 0 1 1 1 0 Membrane transport protein Serinc PF03348.10 CDI86801.1 - 0.027 13.2 12.7 0.033 12.9 8.8 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) SAPS PF04499.10 CDI86801.1 - 0.036 12.6 11.4 0.042 12.4 7.9 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein CPSF100_C PF13299.1 CDI86801.1 - 0.039 14.1 10.8 0.05 13.7 7.5 1.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Ctr PF04145.10 CDI86801.1 - 0.042 13.8 9.9 0.075 13.0 6.9 1.4 1 0 0 1 1 1 0 Ctr copper transporter family DUF853 PF05872.7 CDI86801.1 - 0.061 11.6 11.3 0.071 11.4 7.8 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) FLO_LFY PF01698.11 CDI86801.1 - 0.14 11.0 14.9 0.18 10.5 10.3 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein Peptidase_S49_N PF08496.5 CDI86801.1 - 0.17 11.6 13.8 0.24 11.1 9.6 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal eIF-3_zeta PF05091.7 CDI86801.1 - 0.18 10.3 21.1 0.21 10.1 14.6 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) AIF_C PF14721.1 CDI86801.1 - 0.23 11.7 12.7 0.42 10.8 8.8 1.5 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term RR_TM4-6 PF06459.7 CDI86801.1 - 0.24 11.2 13.7 0.3 10.9 9.5 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF2232 PF09991.4 CDI86801.1 - 0.28 10.1 13.1 0.6 9.0 9.1 1.5 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) DUF4557 PF15101.1 CDI86801.1 - 0.28 10.9 29.0 0.49 10.2 20.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) Tim54 PF11711.3 CDI86801.1 - 0.41 9.1 10.5 0.56 8.7 7.3 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 TFIIA PF03153.8 CDI86801.1 - 0.43 10.4 42.4 0.55 10.0 29.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Folate_carrier PF01770.13 CDI86801.1 - 0.47 8.8 9.3 0.65 8.4 6.5 1.3 1 0 0 1 1 1 0 Reduced folate carrier Pal1 PF08316.6 CDI86801.1 - 0.56 10.6 7.4 1.2 9.5 5.2 1.6 1 0 0 1 1 1 0 Pal1 cell morphology protein Neur_chan_memb PF02932.11 CDI86801.1 - 0.66 9.8 8.4 0.8 9.5 5.8 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region FAM60A PF15396.1 CDI86801.1 - 0.75 9.5 11.7 0.91 9.2 8.1 1.1 1 0 0 1 1 1 0 Protein Family FAM60A AUX_IAA PF02309.11 CDI86801.1 - 0.85 9.3 13.0 1.2 8.8 9.0 1.2 1 0 0 1 1 1 0 AUX/IAA family Dala_Dala_lig_N PF01820.16 CDI86801.1 - 1 9.6 8.4 2 8.7 5.8 1.6 1 0 0 1 1 1 0 D-ala D-ala ligase N-terminus DUF913 PF06025.7 CDI86801.1 - 1 8.0 8.5 1.4 7.6 5.9 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Vma12 PF11712.3 CDI86801.1 - 1.3 8.6 6.3 1.7 8.3 4.4 1.2 1 0 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase OATP PF03137.15 CDI86801.1 - 1.4 6.8 12.2 1.8 6.4 8.4 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Spore_YhcN_YlaJ PF09580.5 CDI86801.1 - 1.5 8.9 17.7 2.2 8.3 12.3 1.2 1 0 0 1 1 1 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) PAT1 PF09770.4 CDI86801.1 - 2 6.5 53.0 2.4 6.2 36.7 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF2215 PF10225.4 CDI86801.1 - 2.1 7.7 11.3 3 7.2 7.8 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) FYDLN_acid PF09538.5 CDI86801.1 - 2.1 8.9 8.5 5.5 7.6 5.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) FAM176 PF14851.1 CDI86801.1 - 2.6 7.7 8.7 4.1 7.0 6.0 1.4 1 0 0 1 1 1 0 FAM176 family FAP PF07174.6 CDI86801.1 - 2.6 7.2 41.0 3.1 6.9 28.4 1.1 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) RNA_pol_Rpb1_5 PF04998.12 CDI86801.1 - 2.7 7.1 10.1 3.3 6.8 7.0 1.1 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 Spc7_N PF15402.1 CDI86801.1 - 2.7 5.8 18.2 3.5 5.5 12.6 1.1 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 DUF4446 PF14584.1 CDI86801.1 - 3.1 7.6 11.9 4.4 7.1 8.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) EIIBC-GUT_N PF03612.9 CDI86801.1 - 3.3 7.2 13.0 5.5 6.5 9.0 1.4 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus YABBY PF04690.8 CDI86801.1 - 3.7 7.7 12.8 5.2 7.2 8.9 1.2 1 0 0 1 1 1 0 YABBY protein Gti1_Pac2 PF09729.4 CDI86801.1 - 4.5 7.0 14.1 6.3 6.6 9.8 1.2 1 0 0 1 1 1 0 Gti1/Pac2 family MMR1 PF08505.5 CDI86801.1 - 4.7 7.1 23.0 6.9 6.6 15.9 1.2 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein DUF822 PF05687.8 CDI86801.1 - 4.8 7.5 11.9 8.2 6.7 8.2 1.4 1 0 0 1 1 1 0 Plant protein of unknown function (DUF822) Paramyxo_ncap PF00973.14 CDI86801.1 - 5.8 5.4 13.4 7.1 5.1 9.3 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein HGTP_anticodon2 PF12745.2 CDI86801.1 - 5.9 5.9 20.3 9.2 5.3 14.1 1.2 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs Baculo_PP31 PF05311.6 CDI86801.1 - 6 6.0 20.2 8.3 5.5 14.0 1.1 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) ATAD4 PF15321.1 CDI86801.1 - 6.2 7.9 16.4 12 6.9 11.3 1.5 1 0 0 1 1 1 0 ATPase family AAA domain containing 4 UPF0565 PF10561.4 CDI86801.1 - 6.4 5.5 14.5 10 4.9 10.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family UPF0565 DUF3260 PF11658.3 CDI86801.1 - 7.4 4.5 17.0 10 4.1 11.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3260) Dicty_REP PF05086.7 CDI86801.1 - 7.6 4.1 13.1 9.1 3.8 9.1 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein SID-1_RNA_chan PF13965.1 CDI86801.1 - 7.9 4.5 10.8 9.4 4.2 7.5 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Pox_RNA_Pol_19 PF05320.7 CDI86801.1 - 7.9 6.1 13.5 10 5.8 9.4 1.1 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit Ycf1 PF05758.7 CDI86801.1 - 8.2 3.9 19.2 9.7 3.7 13.3 1.0 1 0 0 1 1 1 0 Ycf1 RED_N PF07808.8 CDI86801.1 - 9.5 5.3 27.9 19 4.3 19.3 1.5 1 0 0 1 1 1 0 RED-like protein N-terminal region Band_3_cyto PF07565.8 CDI86801.1 - 9.9 5.5 19.4 14 5.1 13.5 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain DUF533 PF04391.7 CDI86802.1 - 0.00011 21.6 2.1 0.00011 21.6 1.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF533) DUF4131 PF13567.1 CDI86802.1 - 0.00016 21.1 0.0 0.00019 20.8 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4131) Spt20 PF12090.3 CDI86802.1 - 0.0012 18.2 1.4 0.0012 18.2 0.9 1.1 1 0 0 1 1 1 1 Spt20 family IncA PF04156.9 CDI86802.1 - 0.0068 16.0 7.6 0.011 15.3 5.3 1.4 1 0 0 1 1 1 1 IncA protein RskA PF10099.4 CDI86802.1 - 0.0069 16.1 2.1 0.0083 15.8 1.5 1.1 1 0 0 1 1 1 1 Anti-sigma-K factor rskA FimP PF09766.4 CDI86802.1 - 0.017 14.1 9.5 0.019 14.0 6.6 1.0 1 0 0 1 1 1 0 Fms-interacting protein DUF912 PF06024.7 CDI86802.1 - 0.02 14.9 1.7 0.028 14.4 1.2 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DDHD PF02862.12 CDI86802.1 - 0.028 14.2 0.5 0.032 14.0 0.4 1.1 1 0 0 1 1 1 0 DDHD domain DUF3260 PF11658.3 CDI86802.1 - 0.029 12.5 0.5 0.031 12.4 0.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3260) Serinc PF03348.10 CDI86802.1 - 0.033 12.9 0.6 0.032 12.9 0.4 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) Ribosomal_S26e PF01283.14 CDI86802.1 - 0.047 13.9 0.3 0.066 13.4 0.2 1.2 1 0 0 1 1 1 0 Ribosomal protein S26e FAM176 PF14851.1 CDI86802.1 - 0.061 13.0 2.5 0.065 12.9 0.3 1.7 2 0 0 2 2 2 0 FAM176 family YABBY PF04690.8 CDI86802.1 - 0.061 13.5 0.3 0.066 13.4 0.2 1.1 1 0 0 1 1 1 0 YABBY protein FHIPEP PF00771.15 CDI86802.1 - 0.067 11.5 2.4 0.076 11.3 1.7 1.0 1 0 0 1 1 1 0 FHIPEP family YfhO PF09586.5 CDI86802.1 - 0.076 11.0 0.1 0.083 10.8 0.1 1.0 1 0 0 1 1 1 0 Bacterial membrane protein YfhO DUF4557 PF15101.1 CDI86802.1 - 0.084 12.7 9.2 0.086 12.6 6.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) DUF3357 PF11837.3 CDI86802.1 - 0.091 12.6 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) Ctr PF04145.10 CDI86802.1 - 0.11 12.5 2.7 0.18 11.8 1.9 1.5 1 1 0 1 1 1 0 Ctr copper transporter family Neurensin PF14927.1 CDI86802.1 - 0.11 11.8 0.2 0.11 11.8 0.2 1.8 2 0 0 2 2 2 0 Neurensin DcuC PF03606.10 CDI86802.1 - 0.13 10.4 0.1 0.16 10.1 0.1 1.1 1 0 0 1 1 1 0 C4-dicarboxylate anaerobic carrier DivIC PF04977.10 CDI86802.1 - 0.14 11.6 11.0 0.23 10.9 7.7 1.3 1 0 0 1 1 1 0 Septum formation initiator Suf PF05843.9 CDI86802.1 - 0.23 11.1 7.4 0.25 11.0 5.2 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) CD20 PF04103.10 CDI86802.1 - 0.31 10.9 2.1 0.24 11.3 0.7 1.4 2 0 0 2 2 1 0 CD20-like family DUF788 PF05620.6 CDI86802.1 - 0.38 10.6 3.5 0.51 10.1 2.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF788) Med15 PF09606.5 CDI86802.1 - 0.42 8.7 22.7 0.46 8.6 15.8 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal VIT1 PF01988.14 CDI86802.1 - 0.46 9.9 1.9 0.58 9.6 1.3 1.3 1 1 0 1 1 1 0 VIT family PCYCGC PF13798.1 CDI86802.1 - 0.67 9.6 3.9 0.86 9.2 2.7 1.2 1 0 0 1 1 1 0 Protein of unknown function with PCYCGC motif TMEM51 PF15345.1 CDI86802.1 - 0.68 9.5 14.2 0.26 10.9 7.4 1.8 1 1 1 2 2 2 0 Transmembrane protein 51 RAB3GAP2_N PF14655.1 CDI86802.1 - 0.92 8.4 7.3 1.1 8.1 5.0 1.1 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus DUF2489 PF10675.4 CDI86802.1 - 1 9.0 11.0 1.8 8.2 7.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2489) Conotoxin PF02950.12 CDI86802.1 - 1.2 10.0 5.8 0.16 12.7 1.1 1.7 2 0 0 2 2 1 0 Conotoxin BAF1_ABF1 PF04684.8 CDI86802.1 - 1.2 7.8 17.1 1.3 7.8 11.9 1.0 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor EphA2_TM PF14575.1 CDI86802.1 - 1.5 9.3 5.3 1.6 9.1 2.7 1.7 1 1 1 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Activator_LAG-3 PF11498.3 CDI86802.1 - 2 7.0 25.1 2.3 6.8 17.4 1.0 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Med3 PF11593.3 CDI86802.1 - 2.1 7.4 20.2 2.8 7.1 14.0 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal PSK PF06404.7 CDI86802.1 - 2.7 8.8 7.4 3.3 8.5 2.7 2.2 2 0 0 2 2 2 0 Phytosulfokine precursor protein (PSK) DUF3270 PF11674.3 CDI86802.1 - 6.6 6.8 6.8 10 6.2 4.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3270) DUF3373 PF11853.3 CDI86802.1 - 7 5.0 8.1 8.6 4.7 5.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) SHR3_chaperone PF08229.6 CDI86802.1 - 8 5.3 8.6 11 4.8 5.9 1.2 1 0 0 1 1 1 0 ER membrane protein SH3 DUF4175 PF13779.1 CDI86802.1 - 9.1 3.8 23.7 11 3.5 16.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) DUF1129 PF06570.6 CDI86804.1 - 0.0026 17.1 4.8 0.0031 16.8 3.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1129) MAGE PF01454.14 CDI86804.1 - 0.0037 16.6 2.7 0.0043 16.4 1.9 1.0 1 0 0 1 1 1 1 MAGE family DUF2199 PF09965.4 CDI86804.1 - 0.047 13.5 0.4 0.054 13.3 0.3 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2199) EIIBC-GUT_N PF03612.9 CDI86804.1 - 0.11 12.1 2.8 0.14 11.7 1.9 1.1 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus DUF2899 PF11449.3 CDI86804.1 - 0.16 11.1 3.5 0.18 10.9 2.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2899) DUF1345 PF07077.6 CDI86804.1 - 0.16 11.4 0.5 0.19 11.2 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1345) UAA PF08449.6 CDI86804.1 - 0.24 10.2 3.9 0.28 10.0 2.7 1.1 1 0 0 1 1 1 0 UAA transporter family Tmem26 PF09772.4 CDI86804.1 - 0.26 10.4 5.6 0.33 10.1 3.9 1.0 1 0 0 1 1 1 0 Transmembrane protein 26 DUF912 PF06024.7 CDI86804.1 - 0.42 10.7 9.3 21 5.2 6.5 2.0 1 1 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DNA_pack_N PF02500.10 CDI86804.1 - 0.55 9.7 4.1 0.59 9.6 2.8 1.0 1 0 0 1 1 1 0 Probable DNA packing protein, N-terminus UPF0233 PF06781.7 CDI86804.1 - 0.71 9.5 4.9 0.69 9.5 0.6 2.0 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0233) RED_N PF07808.8 CDI86804.1 - 1 8.5 11.5 1.3 8.1 8.0 1.2 1 0 0 1 1 1 0 RED-like protein N-terminal region 7tm_1 PF00001.16 CDI86804.1 - 1.6 7.7 5.2 2.8 7.0 3.6 1.6 1 1 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) SprA-related PF12118.3 CDI86804.1 - 1.7 7.9 20.8 2.2 7.5 14.4 1.1 1 0 0 1 1 1 0 SprA-related family TraF PF13728.1 CDI86804.1 - 2.3 7.6 13.7 3 7.2 9.5 1.1 1 0 0 1 1 1 0 F plasmid transfer operon protein 7tm_7 PF08395.7 CDI86804.1 - 7.5 5.4 14.9 8.4 5.3 10.3 1.0 1 0 0 1 1 1 0 7tm Chemosensory receptor DUF4175 PF13779.1 CDI86804.1 - 8.8 3.8 32.4 9.9 3.7 22.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) SprA-related PF12118.3 CDI86805.1 - 0.0008 18.8 10.3 0.0008 18.8 7.1 9.9 6 3 0 7 7 7 1 SprA-related family GPW_gp25 PF04965.9 CDI86806.1 - 0.14 11.6 0.1 6.7 6.3 0.0 2.9 2 1 0 2 2 2 0 Gene 25-like lysozyme Evr1_Alr PF04777.8 CDI86808.1 - 1.5e-09 37.6 0.4 0.00025 20.8 0.0 2.9 2 0 0 2 2 2 2 Erv1 / Alr family Thioredoxin PF00085.15 CDI86808.1 - 6.7e-05 22.5 0.0 0.00013 21.5 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.1 CDI86808.1 - 0.0078 16.2 0.0 0.018 15.0 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.16 CDI86808.1 - 0.032 13.9 0.0 0.075 12.7 0.0 1.5 1 0 0 1 1 1 0 AhpC/TSA family LSM PF01423.17 CDI86811.1 - 2.1e-14 52.7 0.0 2.5e-14 52.5 0.0 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 CDI86811.1 - 1.6e-05 24.6 0.0 2.1e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain MTBP_C PF14920.1 CDI86811.1 - 0.018 14.5 0.0 0.044 13.2 0.0 1.5 1 1 1 2 2 2 0 MDM2-binding PUA PF01472.15 CDI86812.1 - 8e-21 73.5 1.2 1.6e-20 72.5 0.8 1.5 1 0 0 1 1 1 1 PUA domain RR_TM4-6 PF06459.7 CDI86812.1 - 0.093 12.6 10.8 0.11 12.3 7.5 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Zip PF02535.17 CDI86812.1 - 0.11 11.4 0.3 0.13 11.2 0.2 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter PPP4R2 PF09184.6 CDI86812.1 - 0.25 10.8 9.3 0.32 10.4 6.4 1.1 1 0 0 1 1 1 0 PPP4R2 PseudoU_synth_1 PF01416.15 CDI86814.1 - 1.9e-06 28.2 8.9 0.00041 20.7 0.9 3.4 2 1 0 2 2 2 2 tRNA pseudouridine synthase Pox_E2-like PF04497.7 CDI86814.1 - 3.3 5.6 4.6 4.7 5.1 3.2 1.1 1 0 0 1 1 1 0 Poxviridae protein DUF2232 PF09991.4 CDI86815.1 - 0.002 17.1 3.9 0.0023 16.9 2.7 1.1 1 0 0 1 1 1 1 Predicted membrane protein (DUF2232) DUF897 PF05982.7 CDI86815.1 - 0.0066 15.2 4.2 0.0078 15.0 2.9 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF897) IncA PF04156.9 CDI86815.1 - 0.0097 15.5 17.4 0.013 15.1 12.1 1.1 1 0 0 1 1 1 1 IncA protein RAB3GAP2_N PF14655.1 CDI86815.1 - 0.019 14.0 6.9 0.019 13.9 4.8 1.1 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Spt20 PF12090.3 CDI86815.1 - 0.04 13.2 6.3 0.042 13.1 4.4 1.2 1 0 0 1 1 1 0 Spt20 family FimP PF09766.4 CDI86815.1 - 0.043 12.8 12.8 0.048 12.7 8.9 1.1 1 0 0 1 1 1 0 Fms-interacting protein KAP_NTPase PF07693.9 CDI86815.1 - 0.057 12.4 0.5 0.067 12.1 0.3 1.0 1 0 0 1 1 1 0 KAP family P-loop domain CD20 PF04103.10 CDI86815.1 - 0.093 12.6 1.6 0.13 12.1 1.1 1.3 1 1 0 1 1 1 0 CD20-like family AAA_23 PF13476.1 CDI86815.1 - 0.095 13.0 6.3 0.079 13.2 4.4 1.1 1 0 0 1 1 1 0 AAA domain OATP PF03137.15 CDI86815.1 - 0.099 10.6 3.3 0.098 10.6 2.3 1.2 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Activator_LAG-3 PF11498.3 CDI86815.1 - 0.099 11.3 32.2 0.11 11.2 22.3 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Suf PF05843.9 CDI86815.1 - 0.13 11.9 12.8 0.14 11.8 8.9 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Glt_symporter PF03616.9 CDI86815.1 - 0.15 10.5 2.9 0.18 10.2 2.0 1.1 1 0 0 1 1 1 0 Sodium/glutamate symporter PBP1_TM PF14812.1 CDI86815.1 - 0.16 12.3 1.0 0.22 11.8 0.7 1.2 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Band_3_cyto PF07565.8 CDI86815.1 - 0.25 10.7 6.4 0.25 10.8 4.5 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain PAS PF00989.19 CDI86815.1 - 0.4 10.4 6.5 0.72 9.6 4.5 1.5 1 1 0 1 1 1 0 PAS fold Peptidase_U57 PF05582.7 CDI86815.1 - 0.43 9.5 4.6 0.48 9.3 3.2 1.1 1 0 0 1 1 1 0 YabG peptidase U57 DUF1682 PF07946.9 CDI86815.1 - 0.59 8.9 7.7 0.58 8.9 5.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) SprA-related PF12118.3 CDI86815.1 - 0.64 9.2 30.0 0.87 8.8 20.8 1.2 1 0 0 1 1 1 0 SprA-related family Med15 PF09606.5 CDI86815.1 - 0.77 7.8 36.3 1 7.4 25.2 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF4446 PF14584.1 CDI86815.1 - 0.87 9.4 4.5 1.1 9.0 3.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) DUF912 PF06024.7 CDI86815.1 - 1 9.4 7.4 0.5 10.4 3.5 1.7 1 1 1 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Serinc PF03348.10 CDI86815.1 - 1.2 7.7 8.7 1.4 7.5 6.1 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) Phospholip_B PF04916.8 CDI86815.1 - 1.3 7.0 5.4 1.4 6.8 3.7 1.0 1 0 0 1 1 1 0 Phospholipase B Draxin PF15550.1 CDI86815.1 - 1.3 8.6 11.3 1.4 8.4 7.8 1.0 1 0 0 1 1 1 0 Draxin Baculo_PP31 PF05311.6 CDI86815.1 - 1.5 7.9 6.8 1.6 7.9 4.7 1.2 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) Hid1 PF12722.2 CDI86815.1 - 1.6 6.2 7.8 1.8 6.1 5.4 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DDHD PF02862.12 CDI86815.1 - 1.8 8.2 9.2 2 8.1 6.4 1.1 1 0 0 1 1 1 0 DDHD domain R_equi_Vir PF05526.6 CDI86815.1 - 1.9 8.0 11.2 2.7 7.6 7.8 1.2 1 0 0 1 1 1 0 Rhodococcus equi virulence-associated protein HemX PF04375.9 CDI86815.1 - 2 6.9 31.2 2.1 6.8 21.6 1.0 1 0 0 1 1 1 0 HemX MSP1_C PF07462.6 CDI86815.1 - 2.1 6.6 8.3 2.4 6.4 5.8 1.1 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus UCH PF00443.24 CDI86815.1 - 2.5 7.1 6.8 2.3 7.2 4.7 1.1 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase DUF4207 PF13904.1 CDI86815.1 - 2.7 7.2 21.2 3.2 7.0 14.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4207) F-protein PF00469.15 CDI86815.1 - 3 7.1 9.3 5.2 6.3 6.4 1.3 1 0 0 1 1 1 0 Negative factor, (F-Protein) or Nef Peptidase_S15 PF02129.13 CDI86815.1 - 3.1 7.1 11.9 3.8 6.8 8.2 1.1 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) DUF2572 PF10833.3 CDI86815.1 - 3.1 7.1 12.4 3.8 6.8 8.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2572) DUF572 PF04502.8 CDI86815.1 - 3.2 6.8 11.7 3.7 6.6 8.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Prog_receptor PF02161.10 CDI86815.1 - 3.3 6.4 13.7 4.2 6.0 9.5 1.1 1 0 0 1 1 1 0 Progesterone receptor FAM60A PF15396.1 CDI86815.1 - 3.6 7.2 6.3 3.9 7.1 4.4 1.2 1 0 0 1 1 1 0 Protein Family FAM60A TALPID3 PF15324.1 CDI86815.1 - 4.1 4.6 24.0 5.2 4.2 16.6 1.2 1 0 0 1 1 1 0 Hedgehog signalling target PAT1 PF09770.4 CDI86815.1 - 4.6 5.3 31.3 5.3 5.1 21.7 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Peptidase_S49_N PF08496.5 CDI86815.1 - 5 6.9 12.1 7.2 6.3 8.4 1.3 1 1 0 1 1 1 0 Peptidase family S49 N-terminal TFIIA PF03153.8 CDI86815.1 - 6.3 6.5 27.6 7.8 6.2 19.1 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PBP_sp32 PF07222.7 CDI86815.1 - 7 5.7 13.4 7.8 5.5 9.3 1.1 1 0 0 1 1 1 0 Proacrosin binding protein sp32 DUF106 PF01956.11 CDI86815.1 - 7.1 6.1 7.6 8.8 5.8 5.3 1.2 1 0 0 1 1 1 0 Integral membrane protein DUF106 FLO_LFY PF01698.11 CDI86815.1 - 9 5.0 11.0 10 4.8 7.6 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein Herpes_UL87 PF03043.9 CDI86816.1 - 3.6 5.8 8.6 4.6 5.5 6.0 1.1 1 0 0 1 1 1 0 Herpesvirus UL87 family PHD_3 PF13922.1 CDI86816.1 - 4.3 7.6 35.6 4.8 7.5 4.9 3.2 3 0 0 3 3 3 0 PHD domain of transcriptional enhancer, Asx Potyvirid-P3 PF13608.1 CDI86818.1 - 0.0069 15.5 0.8 0.0069 15.5 0.6 2.4 2 1 0 2 2 2 1 Protein P3 of Potyviral polyprotein CLN3 PF02487.12 CDI86818.1 - 0.32 9.7 0.0 0.71 8.5 0.0 1.5 1 0 0 1 1 1 0 CLN3 protein CDK2AP PF09806.4 CDI86819.1 - 0.0056 16.9 13.3 0.0056 16.9 9.2 2.9 3 0 0 3 3 3 2 Cyclin-dependent kinase 2-associated protein BBS2_C PF14782.1 CDI86819.1 - 0.11 11.0 1.6 0.13 10.8 1.1 1.1 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, C-terminal TFIIA PF03153.8 CDI86819.1 - 0.13 12.0 15.3 0.17 11.7 10.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF2371 PF10177.4 CDI86819.1 - 0.25 11.2 2.4 0.4 10.5 0.0 2.2 2 1 0 2 2 2 0 Uncharacterised conserved protein (DUF2371) UCR_Fe-S_N PF10399.4 CDI86819.1 - 0.26 10.5 6.3 0.56 9.4 4.3 1.6 1 0 0 1 1 1 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal PAT1 PF09770.4 CDI86819.1 - 3.3 5.8 20.9 4 5.5 14.5 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF3801 PF12687.2 CDI86819.1 - 9.4 5.7 10.1 0.37 10.3 3.1 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3801) PAT1 PF09770.4 CDI86820.1 - 0.16 10.1 100.2 0.24 9.6 69.5 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 EcsB PF05975.7 CDI86820.1 - 0.88 7.9 6.3 53 2.1 5.6 2.1 2 0 0 2 2 2 0 Bacterial ABC transporter protein EcsB Velvet PF11754.3 CDI86821.1 - 0.041 13.4 2.7 0.045 13.3 1.9 1.0 1 0 0 1 1 1 0 Velvet factor DUF533 PF04391.7 CDI86821.1 - 0.14 11.5 9.3 0.15 11.3 6.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF533) CPSF73-100_C PF11718.3 CDI86821.1 - 0.29 10.4 3.5 0.34 10.2 2.4 1.0 1 0 0 1 1 1 0 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term UPF0560 PF10577.4 CDI86821.1 - 0.44 8.7 12.0 0.43 8.7 8.3 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Oxygenase-NA PF09859.4 CDI86821.1 - 0.5 9.6 5.7 0.47 9.7 4.0 1.1 1 0 0 1 1 1 0 Oxygenase, catalysing oxidative methylation of damaged DNA FCP1_C PF09309.5 CDI86821.1 - 0.57 9.4 6.5 0.57 9.4 4.5 1.1 1 0 0 1 1 1 0 FCP1, C-terminal GRP PF07172.6 CDI86821.1 - 0.65 10.5 4.8 0.7 10.4 3.3 1.1 1 0 0 1 1 1 0 Glycine rich protein family OATP PF03137.15 CDI86821.1 - 1.2 7.0 5.8 1.4 6.9 4.0 1.0 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Spt20 PF12090.3 CDI86821.1 - 1.3 8.3 9.7 1.2 8.4 6.7 1.1 1 0 0 1 1 1 0 Spt20 family DUF4407 PF14362.1 CDI86821.1 - 1.3 7.8 5.1 1.3 7.9 3.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF2722 PF10846.3 CDI86821.1 - 1.5 7.7 10.8 1.5 7.7 7.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Suf PF05843.9 CDI86821.1 - 2.3 7.8 9.0 2.2 7.9 6.2 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DDRGK PF09756.4 CDI86821.1 - 3 7.2 11.3 3.7 6.8 7.9 1.1 1 0 0 1 1 1 0 DDRGK domain PAT1 PF09770.4 CDI86821.1 - 3.4 5.7 16.4 3.1 5.9 11.4 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Med15 PF09606.5 CDI86821.1 - 3.7 5.6 26.3 3.6 5.6 18.2 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Mus7 PF09462.5 CDI86821.1 - 4.5 5.9 8.3 4.1 6.1 5.7 1.0 1 0 0 1 1 1 0 Mus7/MMS22 family DUF853 PF05872.7 CDI86821.1 - 4.9 5.3 7.9 5.1 5.3 5.5 1.0 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) RAB3GAP2_N PF14655.1 CDI86821.1 - 5.2 5.9 8.9 4.9 6.0 6.2 1.2 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Band_3_cyto PF07565.8 CDI86821.1 - 5.3 6.4 6.4 5.1 6.5 4.4 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain DUF775 PF05603.7 CDI86821.1 - 6.7 6.1 7.7 6.8 6.1 5.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF775) BAF1_ABF1 PF04684.8 CDI86821.1 - 7.6 5.2 22.5 6.8 5.4 15.6 1.0 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor DUF4557 PF15101.1 CDI86821.1 - 8.4 6.1 12.9 8 6.2 9.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) RED_N PF07808.8 CDI86821.1 - 8.9 5.4 10.9 9.2 5.4 7.6 1.2 1 0 0 1 1 1 0 RED-like protein N-terminal region SGT1 PF07093.6 CDI86821.1 - 9.3 4.4 9.7 8.9 4.5 6.7 1.0 1 0 0 1 1 1 0 SGT1 protein Rax2 PF12768.2 CDI86822.1 - 5.3 6.1 20.6 5.9 6.0 14.3 1.0 1 0 0 1 1 1 0 Cortical protein marker for cell polarity FAST_1 PF06743.10 CDI86823.1 - 8e-05 22.2 0.5 0.39 10.4 0.0 2.9 2 0 0 2 2 2 2 FAST kinase-like protein, subdomain 1 Me-amine-dh_H PF06433.6 CDI86823.1 - 0.26 9.9 0.0 0.26 9.9 0.0 2.1 2 0 0 2 2 2 0 Methylamine dehydrogenase heavy chain (MADH) Glycos_transf_1 PF00534.15 CDI86825.1 - 3.8e-05 23.1 0.1 3.8e-05 23.1 0.1 3.5 4 0 0 4 4 4 2 Glycosyl transferases group 1 BAF1_ABF1 PF04684.8 CDI86825.1 - 9e-05 21.5 13.8 9e-05 21.5 9.6 11.6 6 3 5 11 11 11 1 BAF1 / ABF1 chromatin reorganising factor IncA PF04156.9 CDI86825.1 - 0.00011 21.8 8.1 0.00011 21.8 5.6 6.7 6 2 0 6 6 6 1 IncA protein Pex14_N PF04695.8 CDI86825.1 - 0.0068 16.4 2.7 0.0068 16.4 1.9 8.4 4 2 3 8 8 8 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Gemini_mov PF01708.11 CDI86825.1 - 0.011 15.2 0.7 0.011 15.2 0.5 4.9 7 0 0 7 7 7 0 Geminivirus putative movement protein LMBR1 PF04791.11 CDI86825.1 - 3.5 6.1 23.6 0.33 9.4 0.4 4.0 4 0 0 4 4 4 0 LMBR1-like membrane protein CBFD_NFYB_HMF PF00808.18 CDI86826.1 - 5.3e-06 26.3 0.4 5.3e-06 26.3 0.3 2.1 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 CDI86826.1 - 0.014 15.5 2.0 0.014 15.5 1.4 2.2 2 0 0 2 2 2 0 Core histone H2A/H2B/H3/H4 GNVR PF13807.1 CDI86826.1 - 0.052 13.3 0.7 0.12 12.1 0.5 1.6 1 0 0 1 1 1 0 G-rich domain on putative tyrosine kinase AAA_22 PF13401.1 CDI86826.1 - 0.28 11.3 2.2 0.51 10.4 1.5 1.6 1 1 0 1 1 1 0 AAA domain FLO_LFY PF01698.11 CDI86826.1 - 0.67 8.7 6.8 0.66 8.7 4.2 1.3 1 1 0 1 1 1 0 Floricaula / Leafy protein Med15 PF09606.5 CDI86826.1 - 3.5 5.6 23.0 1.6 6.8 14.5 1.6 1 1 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal PHD_3 PF13922.1 CDI86826.1 - 4.8 7.5 6.7 20 5.5 4.6 2.1 1 0 0 1 1 1 0 PHD domain of transcriptional enhancer, Asx MIP-T3 PF10243.4 CDI86827.1 - 0.00024 19.7 24.7 0.00024 19.7 17.1 4.3 3 1 1 4 4 4 2 Microtubule-binding protein MIP-T3 CENP-B_dimeris PF09026.5 CDI86827.1 - 0.0012 19.0 5.1 0.0012 19.0 3.5 3.3 3 0 0 3 3 3 1 Centromere protein B dimerisation domain BAF1_ABF1 PF04684.8 CDI86827.1 - 0.0038 16.1 29.1 0.0038 16.1 20.1 7.4 5 2 3 8 8 8 1 BAF1 / ABF1 chromatin reorganising factor DUF3299 PF11736.3 CDI86828.1 - 0.1 12.4 10.4 0.13 12.1 7.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3299) Peptidase_U57 PF05582.7 CDI86828.1 - 0.15 10.9 8.5 0.15 11.0 5.9 1.0 1 0 0 1 1 1 0 YabG peptidase U57 PH_4 PF15404.1 CDI86828.1 - 0.7 9.4 8.0 0.77 9.2 5.5 1.1 1 0 0 1 1 1 0 Pleckstrin homology domain AAA_28 PF13521.1 CDI86828.1 - 1.5 8.7 6.2 2 8.3 4.3 1.3 1 0 0 1 1 1 0 AAA domain DUF4225 PF13988.1 CDI86828.1 - 3.8 6.9 10.2 4.2 6.8 7.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4225) Band_3_cyto PF07565.8 CDI86828.1 - 5.6 6.4 11.6 5.2 6.5 8.0 1.0 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Pex14_N PF04695.8 CDI86828.1 - 5.7 6.9 18.0 7.5 6.5 12.5 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region FAM60A PF15396.1 CDI86828.1 - 6.8 6.3 6.9 6.6 6.4 4.8 1.0 1 0 0 1 1 1 0 Protein Family FAM60A ARF7EP_C PF14949.1 CDI86828.1 - 6.8 7.1 9.8 8.2 6.9 6.8 1.1 1 0 0 1 1 1 0 ARF7 effector protein C-terminus FemAB PF02388.11 CDI86828.1 - 7 5.2 15.3 6.8 5.2 10.6 1.0 1 0 0 1 1 1 0 FemAB family Spc24 PF08286.6 CDI86828.1 - 7.4 6.2 17.3 8.2 6.1 12.0 1.1 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 DUF1510 PF07423.6 CDI86829.1 - 2.4 7.5 33.0 2.6 7.3 22.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Ribosomal_60s PF00428.14 CDI86830.1 - 1.5e-23 82.9 11.6 1.9e-23 82.6 8.0 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein NIL PF09383.5 CDI86830.1 - 0.1 12.2 0.2 0.14 11.7 0.1 1.2 1 0 0 1 1 1 0 NIL domain DUF4207 PF13904.1 CDI86831.1 - 0.0052 16.2 2.8 0.0052 16.2 1.9 4.8 2 1 1 4 4 4 1 Domain of unknown function (DUF4207) SSP160 PF06933.6 CDI86832.1 - 0.51 8.2 14.4 0.59 8.0 10.0 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 E7 PF00527.13 CDI86832.1 - 0.65 10.1 15.9 0.49 10.5 0.5 2.4 2 0 0 2 2 2 0 E7 protein, Early protein FimP PF09766.4 CDI86832.1 - 3.4 6.6 37.7 0.042 12.9 1.3 2.1 2 0 0 2 2 2 0 Fms-interacting protein Peptidase_S46 PF10459.4 CDI86832.1 - 3.8 5.8 23.4 4.5 5.5 16.2 1.1 1 0 0 1 1 1 0 Peptidase S46 Folliculin PF11704.3 CDI86832.1 - 4.2 6.9 15.3 7.3 6.1 6.0 2.2 2 0 0 2 2 2 0 Vesicle coat protein involved in Golgi to plasma membrane transport MAT1 PF06391.8 CDI86832.1 - 5 6.6 23.2 0.15 11.6 6.6 2.1 2 0 0 2 2 2 0 CDK-activating kinase assembly factor MAT1 Apc15p PF05841.6 CDI86832.1 - 7.8 7.2 27.4 0.62 10.8 10.2 2.3 2 0 0 2 2 2 0 Apc15p protein FAM176 PF14851.1 CDI86832.1 - 9.6 5.8 12.4 9.8 5.8 5.4 2.1 2 0 0 2 2 2 0 FAM176 family DUF966 PF06136.8 CDI86832.1 - 9.7 5.4 25.0 12 5.2 17.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) BAF1_ABF1 PF04684.8 CDI86832.1 - 9.9 4.8 61.7 0.0089 14.9 24.2 2.1 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor PAT1 PF09770.4 CDI86833.1 - 0.0031 15.8 71.3 0.0038 15.5 49.5 1.1 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 RskA PF10099.4 CDI86833.1 - 0.94 9.1 44.9 0.43 10.3 6.5 2.5 2 1 0 2 2 2 0 Anti-sigma-K factor rskA LMBR1 PF04791.11 CDI86834.1 - 1.6 7.1 13.7 2.2 6.7 9.5 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Neur_chan_memb PF02932.11 CDI86834.1 - 3.2 7.5 20.8 6.5 6.5 14.4 1.6 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Asp-B-Hydro_N PF05279.6 CDI86834.1 - 4 7.2 28.6 8.2 6.2 19.8 1.4 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Ycf1 PF05758.7 CDI86834.1 - 7.1 4.2 24.4 8.8 3.8 16.9 1.2 1 0 0 1 1 1 0 Ycf1 BTV_NS2 PF04514.7 CDI86834.1 - 9.9 4.9 26.4 16 4.2 18.3 1.3 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 DUF1777 PF08648.7 CDI86835.1 - 0.06 13.0 72.2 23 4.6 50.0 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF1777) MIP-T3 PF10243.4 CDI86835.1 - 0.6 8.5 17.3 0.65 8.3 12.0 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 PRP38_assoc PF12871.2 CDI86835.1 - 7.5 7.1 93.9 1.5e+04 -13.2 65.1 2.8 1 1 0 1 1 1 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term PRP21_like_P PF12230.3 CDI86837.1 - 0.16 11.4 15.2 0.23 10.9 10.6 1.2 1 0 0 1 1 1 0 Pre-mRNA splicing factor PRP21 like protein Med15 PF09606.5 CDI86837.1 - 0.19 9.9 37.5 0.24 9.5 26.0 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF605 PF04652.11 CDI86837.1 - 1.1 8.5 26.0 1.5 8.1 18.0 1.1 1 0 0 1 1 1 0 Vta1 like Cas_DxTHG PF09455.5 CDI86839.1 - 0.56 9.2 12.6 0.61 9.1 7.7 1.7 1 1 1 2 2 2 0 CRISPR-associated (Cas) DxTHG family CDC45 PF02724.9 CDI86840.1 - 0.091 10.7 26.7 0.1 10.6 18.5 1.0 1 0 0 1 1 1 0 CDC45-like protein DDRGK PF09756.4 CDI86840.1 - 0.56 9.5 40.8 0.72 9.2 28.3 1.2 1 0 0 1 1 1 0 DDRGK domain Utp14 PF04615.8 CDI86840.1 - 0.65 8.0 34.5 0.74 7.9 23.9 1.0 1 0 0 1 1 1 0 Utp14 protein SAPS PF04499.10 CDI86840.1 - 1.5 7.4 27.5 1.5 7.3 19.0 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF4045 PF13254.1 CDI86840.1 - 1.6 7.9 27.8 1.8 7.7 19.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) NPR3 PF03666.8 CDI86840.1 - 1.8 7.0 29.6 2.1 6.8 20.5 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DDHD PF02862.12 CDI86840.1 - 2.2 8.0 27.4 3.3 7.4 19.0 1.3 1 0 0 1 1 1 0 DDHD domain DUF1510 PF07423.6 CDI86840.1 - 2.8 7.2 37.8 3.2 7.0 26.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Rtf2 PF04641.7 CDI86840.1 - 2.8 7.0 30.9 3.5 6.7 21.4 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger CKAP2_C PF15297.1 CDI86840.1 - 3.5 6.3 31.7 4.1 6.1 22.0 1.1 1 0 0 1 1 1 0 Cytoskeleton-associated protein 2 C-terminus MRP-S31 PF15433.1 CDI86840.1 - 3.7 6.8 35.3 4.8 6.5 24.5 1.1 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 Raftlin PF15250.1 CDI86840.1 - 3.7 5.9 30.2 4.3 5.7 20.9 1.0 1 0 0 1 1 1 0 Raftlin Zip PF02535.17 CDI86840.1 - 4.2 6.2 15.0 5.9 5.8 10.4 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter CENP-T PF15511.1 CDI86840.1 - 4.8 6.3 28.3 5.5 6.1 19.6 1.0 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Tim54 PF11711.3 CDI86840.1 - 5.2 5.5 22.3 7 5.1 15.5 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DUF913 PF06025.7 CDI86840.1 - 5.4 5.6 19.8 6.5 5.3 13.7 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DUF1168 PF06658.7 CDI86840.1 - 7.3 6.1 39.6 8.8 5.8 27.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) Paramyxo_ncap PF00973.14 CDI86840.1 - 7.4 5.1 30.2 8.2 4.9 20.9 1.0 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein FAM60A PF15396.1 CDI86840.1 - 7.7 6.2 28.5 8.9 5.9 19.7 1.0 1 0 0 1 1 1 0 Protein Family FAM60A Hid1 PF12722.2 CDI86840.1 - 8.2 3.9 34.4 9.2 3.7 23.8 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Spore_coat_CotO PF14153.1 CDI86840.1 - 8.9 5.7 48.8 12 5.3 33.8 1.1 1 0 0 1 1 1 0 Spore coat protein CotO BAF1_ABF1 PF04684.8 CDI86841.1 - 0.005 15.7 14.3 0.0058 15.5 9.9 1.1 1 0 0 1 1 1 1 BAF1 / ABF1 chromatin reorganising factor POR PF01558.13 CDI86841.1 - 0.058 13.2 0.6 0.059 13.2 0.5 1.1 1 0 0 1 1 1 0 Pyruvate ferredoxin/flavodoxin oxidoreductase DUF2722 PF10846.3 CDI86841.1 - 0.19 10.7 7.0 0.17 10.8 4.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Med15 PF09606.5 CDI86841.1 - 0.4 8.8 22.2 0.43 8.7 15.4 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal VAD1-2 PF15310.1 CDI86841.1 - 0.7 9.5 6.8 0.68 9.5 4.7 1.0 1 0 0 1 1 1 0 Vitamin A-deficiency (VAD) rat model signalling DUF4557 PF15101.1 CDI86841.1 - 1.4 8.7 7.1 1.4 8.7 4.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) MCPVI PF02993.9 CDI86841.1 - 1.7 8.7 6.4 1.8 8.6 4.4 1.0 1 0 0 1 1 1 0 Minor capsid protein VI DivIC PF04977.10 CDI86841.1 - 2.3 7.7 11.0 2.8 7.5 7.6 1.1 1 0 0 1 1 1 0 Septum formation initiator CDK2AP PF09806.4 CDI86841.1 - 3 8.0 11.0 3.8 7.7 7.7 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein Activator_LAG-3 PF11498.3 CDI86841.1 - 3.5 6.2 19.6 3.4 6.2 13.6 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 ATP-synt_E PF05680.7 CDI86841.1 - 3.9 7.5 7.8 4.6 7.2 5.4 1.3 1 0 0 1 1 1 0 ATP synthase E chain FAM117 PF15388.1 CDI86841.1 - 6.9 5.8 8.5 7.5 5.6 5.9 1.0 1 0 0 1 1 1 0 Protein Family FAM117 RIC3 PF15361.1 CDI86844.1 - 0.31 11.2 13.8 0.33 11.1 9.6 1.0 1 0 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 SelP_N PF04592.9 CDI86844.1 - 1.8 7.9 23.0 2 7.7 16.0 1.0 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Zip PF02535.17 CDI86844.1 - 2.8 6.8 15.4 2.8 6.8 10.7 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter Peptidase_S49_N PF08496.5 CDI86844.1 - 4.1 7.1 11.0 4.3 7.1 7.6 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal MDFI PF15316.1 CDI86844.1 - 4.4 7.2 7.0 5 7.0 4.8 1.0 1 0 0 1 1 1 0 MyoD family inhibitor FNIP_N PF14636.1 CDI86844.1 - 4.5 7.7 13.7 4.8 7.6 9.5 1.1 1 0 0 1 1 1 0 Folliculin-interacting protein N-terminus Asn_synthase PF00733.16 CDI86844.1 - 6.7 6.1 8.4 7.3 6.0 5.8 1.0 1 0 0 1 1 1 0 Asparagine synthase Spt20 PF12090.3 CDI86845.1 - 0.061 12.6 2.4 0.083 12.2 0.1 2.1 2 0 0 2 2 2 0 Spt20 family SR-25 PF10500.4 CDI86845.1 - 8.5 5.7 23.4 0.11 11.9 6.3 3.1 3 0 0 3 3 3 0 Nuclear RNA-splicing-associated protein Macoilin PF09726.4 CDI86846.1 - 0.0057 15.0 41.2 0.0068 14.7 28.5 1.1 1 0 0 1 1 1 1 Transmembrane protein DUF4045 PF13254.1 CDI86846.1 - 0.01 15.1 35.7 0.014 14.7 24.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Med15 PF09606.5 CDI86846.1 - 0.016 13.4 95.9 0.019 13.1 66.5 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal PAT1 PF09770.4 CDI86846.1 - 0.018 13.3 78.2 0.021 13.0 54.2 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 MIP-T3 PF10243.4 CDI86846.1 - 0.034 12.6 57.3 0.044 12.2 39.7 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Daxx PF03344.10 CDI86846.1 - 0.062 11.7 42.2 0.071 11.5 29.3 1.1 1 0 0 1 1 1 0 Daxx Family TFIIF_alpha PF05793.7 CDI86846.1 - 0.59 8.4 38.1 0.82 7.9 26.4 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Utp14 PF04615.8 CDI86846.1 - 0.63 8.1 55.8 0.8 7.8 38.7 1.1 1 0 0 1 1 1 0 Utp14 protein Asp-B-Hydro_N PF05279.6 CDI86846.1 - 0.7 9.6 38.0 0.95 9.2 26.4 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region SOBP PF15279.1 CDI86846.1 - 1.2 9.4 38.8 1.8 8.8 26.9 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein PLRV_ORF5 PF01690.12 CDI86846.1 - 2.1 7.4 38.5 2.5 7.1 26.7 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein DUF4613 PF15390.1 CDI86846.1 - 2.5 6.1 40.8 2.7 6.0 28.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) Borrelia_P83 PF05262.6 CDI86846.1 - 4.9 5.3 42.9 5.6 5.1 29.7 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF572 PF04502.8 CDI86846.1 - 6.7 5.8 49.6 9.5 5.3 34.4 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) SR-25 PF10500.4 CDI86847.1 - 0.0002 20.9 20.6 0.0002 20.9 14.2 19.0 11 8 3 16 16 16 2 Nuclear RNA-splicing-associated protein BIV_Env PF05858.7 CDI86848.1 - 0.0011 17.0 3.5 0.0011 17.0 2.4 1.4 1 1 0 1 1 1 1 Bovine immunodeficiency virus surface protein (SU) SR-25 PF10500.4 CDI86848.1 - 0.0019 17.6 11.6 0.0019 17.6 8.0 2.6 2 1 0 2 2 2 1 Nuclear RNA-splicing-associated protein CAF-1_p150 PF11600.3 CDI86848.1 - 0.022 14.1 39.1 0.039 13.3 13.2 2.1 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Baculo_PP31 PF05311.6 CDI86848.1 - 0.15 11.2 26.5 0.64 9.2 10.1 2.2 2 0 0 2 2 2 0 Baculovirus 33KDa late protein (PP31) SecG PF03840.9 CDI86848.1 - 2.3 8.0 5.7 2 8.2 1.3 2.6 2 0 0 2 2 2 0 Preprotein translocase SecG subunit LysE PF01810.13 CDI86848.1 - 3.9 6.6 8.8 3.8 6.7 0.1 3.2 3 1 1 4 4 4 0 LysE type translocator DUF1510 PF07423.6 CDI86848.1 - 8.6 5.6 31.4 1.6 8.0 1.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) RRM_5 PF13893.1 CDI86849.1 - 0.00015 21.5 0.0 0.00024 20.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CDI86849.1 - 0.0003 20.3 0.0 0.00055 19.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CDI86849.1 - 0.00047 20.0 0.0 0.00081 19.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF2722 PF10846.3 CDI86849.1 - 0.018 14.1 17.0 0.055 12.4 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2722) RRM_3 PF08777.6 CDI86849.1 - 0.79 9.6 0.0 0.79 9.6 0.0 2.7 3 0 0 3 3 3 0 RNA binding motif CD99L2 PF12301.3 CDI86849.1 - 1.6 8.4 9.3 0.42 10.2 2.1 2.2 2 0 0 2 2 2 0 CD99 antigen like protein 2 SAGA-Tad1 PF12767.2 CDI86849.1 - 1.7 8.2 16.6 2.1 7.9 8.5 2.1 2 0 0 2 2 2 0 Transcriptional regulator of RNA polII, SAGA, subunit TFIIA PF03153.8 CDI86849.1 - 1.7 8.4 26.2 9.6 5.9 0.2 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Band_3_cyto PF07565.8 CDI86849.1 - 8.5 5.8 8.2 29 4.0 5.7 2.0 1 1 0 1 1 1 0 Band 3 cytoplasmic domain ADK PF00406.17 CDI86850.1 - 5.2e-21 75.0 0.0 2.1e-17 63.4 0.0 3.2 1 1 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.1 CDI86850.1 - 6.7e-06 26.9 0.0 1.2e-05 26.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 CDI86850.1 - 7.3e-06 26.3 0.0 0.00022 21.5 0.0 2.7 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.1 CDI86850.1 - 9.6e-06 25.5 5.3 1.1e-05 25.2 0.0 3.3 2 1 0 2 2 2 1 AAA domain KTI12 PF08433.5 CDI86850.1 - 0.0016 17.7 0.1 0.0016 17.7 0.0 2.3 2 1 0 2 2 2 1 Chromatin associated protein KTI12 AAA_28 PF13521.1 CDI86850.1 - 0.0097 15.8 0.1 0.0097 15.8 0.1 2.7 2 1 0 2 2 2 1 AAA domain Mg_chelatase PF01078.16 CDI86850.1 - 0.022 13.9 0.1 0.022 13.9 0.0 2.2 2 1 1 3 3 3 0 Magnesium chelatase, subunit ChlI DUF912 PF06024.7 CDI86850.1 - 0.026 14.5 0.7 0.069 13.2 0.1 1.9 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Viral_Beta_CD PF04530.7 CDI86850.1 - 0.038 14.1 1.0 0.082 13.0 0.7 1.5 1 0 0 1 1 1 0 Viral Beta C/D like family DUF3270 PF11674.3 CDI86850.1 - 0.04 13.9 0.9 0.04 13.9 0.7 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3270) Spt20 PF12090.3 CDI86850.1 - 0.38 10.0 9.2 2 7.7 3.6 2.3 2 0 0 2 2 2 0 Spt20 family PsbQ PF05757.6 CDI86850.1 - 1.8 7.9 10.6 0.18 11.2 2.9 2.6 3 0 0 3 3 3 0 Oxygen evolving enhancer protein 3 (PsbQ) Suf PF05843.9 CDI86850.1 - 9 5.9 10.0 12 5.5 2.8 2.2 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) SR-25 PF10500.4 CDI86851.1 - 0.0011 18.5 20.3 0.0013 18.2 14.1 1.2 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein DUF4175 PF13779.1 CDI86851.1 - 0.13 9.9 30.9 0.12 10.0 21.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Med15 PF09606.5 CDI86851.1 - 0.28 9.3 35.8 0.25 9.4 24.8 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Di19_C PF14571.1 CDI86851.1 - 0.42 10.9 17.6 0.5 10.7 12.2 1.1 1 0 0 1 1 1 0 Stress-induced protein Di19, C-terminal CAF-1_p150 PF11600.3 CDI86851.1 - 0.43 9.9 24.1 0.49 9.7 16.7 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF3801 PF12687.2 CDI86851.1 - 0.86 9.1 18.2 1.2 8.6 12.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3801) PRCC PF10253.4 CDI86851.1 - 0.89 10.2 23.4 1.1 9.9 16.2 1.2 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting Ebola_NP PF05505.7 CDI86851.1 - 1.4 6.9 15.0 1.5 6.7 10.4 1.0 1 0 0 1 1 1 0 Ebola nucleoprotein TAF1D PF15333.1 CDI86851.1 - 1.9 8.1 16.7 2.3 7.9 11.6 1.0 1 0 0 1 1 1 0 TATA box-binding protein-associated factor 1D PAT1 PF09770.4 CDI86851.1 - 2.5 6.2 33.0 2.6 6.1 22.9 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF4407 PF14362.1 CDI86851.1 - 2.8 6.7 11.3 2.3 7.0 7.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF605 PF04652.11 CDI86851.1 - 4.2 6.6 28.1 5.3 6.3 19.5 1.1 1 0 0 1 1 1 0 Vta1 like Suf PF05843.9 CDI86851.1 - 5.5 6.6 26.2 5.7 6.5 18.1 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Herpes_TAF50 PF03326.8 CDI86851.1 - 6.3 5.6 25.5 6.6 5.5 17.7 1.0 1 0 0 1 1 1 0 Herpesvirus transcription activation factor (transactivator) Daxx PF03344.10 CDI86851.1 - 9.1 4.6 22.0 10 4.4 15.3 1.0 1 0 0 1 1 1 0 Daxx Family DUF3381 PF11861.3 CDI86851.1 - 9.3 5.7 13.8 11 5.4 9.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) Methyltransf_26 PF13659.1 CDI86852.1 - 0.0013 18.7 5.2 0.053 13.5 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain N6_N4_Mtase PF01555.13 CDI86852.1 - 0.14 11.6 0.0 0.19 11.1 0.0 1.2 1 0 0 1 1 1 0 DNA methylase TF_Zn_Ribbon PF08271.7 CDI86853.1 - 0.31 10.4 0.5 0.78 9.1 0.3 1.7 1 0 0 1 1 1 0 TFIIB zinc-binding zf-DHHC PF01529.15 CDI86853.1 - 0.97 8.8 17.5 1.6 8.0 0.3 5.1 5 0 0 5 5 5 0 DHHC palmitoyltransferase SR-25 PF10500.4 CDI86854.1 - 0.12 11.7 11.1 0.2 11.0 7.7 1.3 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein Synaptobrevin PF00957.16 CDI86855.1 - 0.043 13.4 1.8 0.17 11.5 1.2 2.0 1 0 0 1 1 1 0 Synaptobrevin PP2C PF00481.16 CDI86856.1 - 2.8e-59 200.5 10.2 3e-51 174.2 0.0 4.3 5 0 0 5 5 5 3 Protein phosphatase 2C zf-DHHC PF01529.15 CDI86856.1 - 0.14 11.5 1.2 1.1 8.6 0.2 2.3 2 0 0 2 2 2 0 DHHC palmitoyltransferase AAA_23 PF13476.1 CDI86856.1 - 0.98 9.7 25.6 0.16 12.2 9.4 2.4 2 0 0 2 2 2 0 AAA domain Cytochrom_B561 PF03188.11 CDI86857.1 - 2.4e-27 95.4 10.1 2.4e-27 95.4 7.0 1.9 2 0 0 2 2 2 1 Eukaryotic cytochrome b561 Ost4 PF10215.4 CDI86857.1 - 0.18 11.3 8.1 0.49 9.9 0.6 2.6 2 0 0 2 2 2 0 Oligosaccaryltransferase Mito_morph_reg PF14972.1 CDI86857.1 - 0.29 10.5 1.4 0.33 10.3 0.3 1.5 2 0 0 2 2 2 0 Mitochondrial morphogenesis regulator Ni_hydr_CYTB PF01292.15 CDI86857.1 - 0.95 8.8 12.5 0.062 12.6 3.4 2.1 1 1 0 1 1 1 0 Prokaryotic cytochrome b561 SUR7 PF06687.7 CDI86857.1 - 4.6 6.7 15.2 1.5 8.3 7.2 2.0 2 0 0 2 2 2 0 SUR7/PalI family Pal1 PF08316.6 CDI86858.1 - 0.026 14.9 1.0 0.061 13.7 0.7 1.6 1 0 0 1 1 1 0 Pal1 cell morphology protein Gag_spuma PF03276.9 CDI86858.1 - 0.029 12.7 11.0 0.066 11.5 7.6 1.5 1 0 0 1 1 1 0 Spumavirus gag protein Ycf1 PF05758.7 CDI86858.1 - 0.077 10.7 0.3 0.1 10.2 0.2 1.1 1 0 0 1 1 1 0 Ycf1 Spt20 PF12090.3 CDI86858.1 - 0.089 12.1 4.8 0.16 11.3 3.3 1.3 1 0 0 1 1 1 0 Spt20 family FAST_1 PF06743.10 CDI86858.1 - 0.12 12.0 0.0 0.59 9.8 0.0 2.0 2 0 0 2 2 2 0 FAST kinase-like protein, subdomain 1 FHIPEP PF00771.15 CDI86858.1 - 0.2 9.9 0.9 0.28 9.4 0.7 1.1 1 0 0 1 1 1 0 FHIPEP family UPF0560 PF10577.4 CDI86858.1 - 0.24 9.6 9.5 0.39 8.9 6.6 1.3 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 PAT1 PF09770.4 CDI86858.1 - 0.27 9.4 19.0 0.42 8.8 13.2 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Med15 PF09606.5 CDI86858.1 - 0.91 7.6 31.3 2 6.5 21.7 1.5 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal OATP PF03137.15 CDI86858.1 - 1.8 6.5 3.0 3.1 5.7 2.1 1.3 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family DUF4175 PF13779.1 CDI86858.1 - 2.6 5.6 25.2 4 5.0 17.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Hid1 PF12722.2 CDI86858.1 - 2.6 5.6 5.4 3.9 5.0 3.7 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Suf PF05843.9 CDI86858.1 - 2.7 7.6 13.8 6.2 6.4 9.6 1.5 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) TFIIA PF03153.8 CDI86858.1 - 3.8 7.2 19.3 1.8 8.3 10.9 1.9 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit DUF775 PF05603.7 CDI86858.1 - 3.9 6.9 9.2 7.4 6.0 6.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF775) Pap_E4 PF02711.9 CDI86858.1 - 6.6 7.6 11.7 2.5 8.9 5.6 2.1 2 0 0 2 2 1 0 E4 protein Pex14_N PF04695.8 CDI86858.1 - 7.6 6.5 17.2 2.2 8.3 8.3 2.3 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Neur_chan_memb PF02932.11 CDI86858.1 - 9.2 6.0 6.6 2.3 8.0 0.9 2.1 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region FlxA PF14282.1 CDI86860.1 - 0.078 12.9 12.5 1.3 9.0 5.2 2.3 2 0 0 2 2 2 0 FlxA-like protein TMF_DNA_bd PF12329.3 CDI86860.1 - 0.09 12.5 0.7 0.09 12.5 0.5 2.6 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Pollen_allerg_2 PF01620.11 CDI86860.1 - 0.42 10.9 24.7 2.4 8.4 10.7 2.1 1 1 1 2 2 2 0 Ribonuclease (pollen allergen) Prefoldin PF02996.12 CDI86860.1 - 0.59 9.7 8.9 2.8 7.6 2.7 2.3 2 0 0 2 2 2 0 Prefoldin subunit Rabaptin PF03528.10 CDI86860.1 - 1.6 8.7 12.5 0.5 10.3 4.9 2.1 2 0 0 2 2 2 0 Rabaptin Dynactin_p62 PF05502.8 CDI86860.1 - 2.2 6.9 9.3 2.7 6.6 6.5 1.0 1 0 0 1 1 1 0 Dynactin p62 family DUF2611 PF11022.3 CDI86860.1 - 2.7 8.1 9.3 0.26 11.3 0.8 2.5 1 1 0 2 2 2 0 Protein of unknown function (DUF2611) Tnp_P_element PF12017.3 CDI86860.1 - 2.9 7.0 4.8 9 5.4 2.0 2.0 2 0 0 2 2 2 0 Transposase protein RR_TM4-6 PF06459.7 CDI86860.1 - 4.6 7.0 8.4 6.1 6.6 5.8 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CDC27 PF09507.5 CDI86860.1 - 8.4 5.4 12.0 11 5.1 8.3 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Med15 PF09606.5 CDI86862.1 - 0.00028 19.2 62.2 0.00033 19.0 43.1 1.1 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal AAA_23 PF13476.1 CDI86862.1 - 0.006 16.9 15.6 0.0071 16.6 10.8 1.1 1 0 0 1 1 1 1 AAA domain DUF605 PF04652.11 CDI86862.1 - 0.0092 15.4 49.9 0.011 15.1 34.6 1.0 1 0 0 1 1 1 1 Vta1 like PAT1 PF09770.4 CDI86862.1 - 0.011 14.0 48.8 0.012 13.8 33.9 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 FtsL PF04999.8 CDI86864.1 - 0.099 12.3 6.2 0.22 11.2 4.3 1.5 1 0 0 1 1 1 0 Cell division protein FtsL TFIIA PF03153.8 CDI86864.1 - 6.5 6.5 10.3 8.1 6.2 7.1 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PAT1 PF09770.4 CDI86865.1 - 0.00034 19.0 126.6 0.00038 18.8 87.8 1.0 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 Utp14 PF04615.8 CDI86865.1 - 0.062 11.4 65.4 0.074 11.2 45.4 1.0 1 0 0 1 1 1 0 Utp14 protein Daxx PF03344.10 CDI86865.1 - 0.31 9.4 55.6 0.36 9.2 38.5 1.1 1 0 0 1 1 1 0 Daxx Family SOBP PF15279.1 CDI86865.1 - 1.7 8.9 54.8 2.7 8.3 38.0 1.4 1 0 0 1 1 1 0 Sine oculis-binding protein PLRV_ORF5 PF01690.12 CDI86865.1 - 4 6.4 52.8 5 6.1 36.6 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein DUF605 PF04652.11 CDI86866.1 - 6.2e-05 22.5 54.8 0.0021 17.5 19.3 2.1 2 0 0 2 2 2 2 Vta1 like DUF3464 PF11947.3 CDI86866.1 - 0.0052 16.2 0.4 0.0052 16.2 0.3 3.7 3 1 0 3 3 2 1 Protein of unknown function (DUF3464) Senescence_reg PF04520.8 CDI86866.1 - 0.022 15.2 10.3 0.022 15.2 7.1 4.1 2 1 0 2 2 1 0 Senescence regulator LicD PF04991.8 CDI86866.1 - 0.059 13.4 2.9 0.062 13.4 0.1 2.0 2 0 0 2 2 2 0 LicD family DUF1510 PF07423.6 CDI86866.1 - 0.23 10.8 35.0 0.43 9.9 9.4 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1510) Daxx PF03344.10 CDI86866.1 - 0.49 8.8 32.3 0.83 8.0 7.1 2.2 2 0 0 2 2 2 0 Daxx Family Peptidase_S49_N PF08496.5 CDI86866.1 - 0.56 9.9 16.4 11 5.8 0.4 2.9 3 0 0 3 3 3 0 Peptidase family S49 N-terminal Nop16 PF09420.5 CDI86866.1 - 1.2 9.2 26.0 0.022 14.8 3.7 2.5 2 0 0 2 2 2 0 Ribosome biogenesis protein Nop16 FYDLN_acid PF09538.5 CDI86866.1 - 4.2 7.9 16.1 12 6.4 5.5 2.8 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) DUF2058 PF09831.4 CDI86866.1 - 6.8 6.5 40.8 4.6 7.0 18.9 2.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2058) Mnd1 PF03962.10 CDI86866.1 - 7.3 6.2 32.8 2.4 7.7 16.7 2.3 2 0 0 2 2 2 0 Mnd1 family WD40 PF00400.27 CDI86867.1 - 5.5e-30 102.1 2.0 9.9e-14 50.6 0.2 3.5 3 0 0 3 3 3 3 WD domain, G-beta repeat NLE PF08154.7 CDI86867.1 - 4.8e-06 26.4 0.1 9.1e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 NLE (NUC135) domain eIF2A PF08662.6 CDI86867.1 - 0.079 12.6 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor eIF2A Shadoo PF14999.1 CDI86867.1 - 1.6 8.6 21.7 0.44 10.3 0.8 2.7 2 0 0 2 2 2 0 Shadow of prion protein, neuroprotective CAF-1_p150 PF11600.3 CDI86868.1 - 0.089 12.1 21.9 0.11 11.8 15.2 1.0 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal SelP_N PF04592.9 CDI86868.1 - 0.2 10.9 23.1 0.23 10.8 16.0 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Serinc PF03348.10 CDI86868.1 - 0.37 9.4 16.5 0.42 9.2 11.5 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) FLO_LFY PF01698.11 CDI86868.1 - 0.38 9.5 19.9 0.41 9.4 13.8 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein SprA-related PF12118.3 CDI86868.1 - 0.44 9.8 51.4 0.59 9.4 35.6 1.2 1 0 0 1 1 1 0 SprA-related family Gag_spuma PF03276.9 CDI86868.1 - 0.59 8.3 34.9 0.62 8.3 24.2 1.2 1 0 0 1 1 1 0 Spumavirus gag protein Med15 PF09606.5 CDI86868.1 - 0.69 8.0 67.5 0.77 7.8 46.8 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DDHD PF02862.12 CDI86868.1 - 1.3 8.7 19.5 1.4 8.6 13.5 1.1 1 0 0 1 1 1 0 DDHD domain MgsA_C PF12002.3 CDI86868.1 - 2.7 7.6 15.9 3.4 7.3 11.0 1.1 1 0 0 1 1 1 0 MgsA AAA+ ATPase C terminal Hamartin PF04388.7 CDI86868.1 - 3 6.4 21.3 3.5 6.1 14.7 1.0 1 0 0 1 1 1 0 Hamartin protein BTV_NS2 PF04514.7 CDI86868.1 - 3.4 6.4 15.2 3.7 6.3 10.5 1.0 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 RR_TM4-6 PF06459.7 CDI86868.1 - 4 7.2 22.8 4.9 6.9 15.8 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF4045 PF13254.1 CDI86868.1 - 4.4 6.4 21.2 4.8 6.3 14.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) DUF3984 PF13136.1 CDI86868.1 - 4.8 6.3 21.4 6.1 5.9 14.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3984) CDC45 PF02724.9 CDI86868.1 - 5 5.0 17.7 5.8 4.8 12.3 1.1 1 0 0 1 1 1 0 CDC45-like protein Macoilin PF09726.4 CDI86868.1 - 5.8 5.0 22.0 6.2 4.9 15.2 1.1 1 0 0 1 1 1 0 Transmembrane protein VIT1 PF01988.14 CDI86868.1 - 6.1 6.2 13.1 13 5.1 9.1 1.5 1 1 0 1 1 1 0 VIT family Spore_coat_CotO PF14153.1 CDI86868.1 - 6.2 6.2 29.1 6.9 6.0 20.2 1.2 1 0 0 1 1 1 0 Spore coat protein CotO DUF1510 PF07423.6 CDI86868.1 - 6.4 6.0 23.6 7.5 5.8 16.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Pneumo_phosprot PF02478.11 CDI86868.1 - 6.9 6.1 10.6 8.1 5.8 7.4 1.1 1 0 0 1 1 1 0 Pneumovirus phosphoprotein FAM60A PF15396.1 CDI86868.1 - 7.1 6.3 18.9 7.8 6.1 13.1 1.1 1 0 0 1 1 1 0 Protein Family FAM60A DUF1980 PF09323.5 CDI86868.1 - 7.2 6.3 14.8 9.9 5.8 10.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) Spc7_N PF15402.1 CDI86868.1 - 7.3 4.4 29.5 8.5 4.2 20.5 1.1 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 Hid1 PF12722.2 CDI86868.1 - 7.4 4.1 21.3 7.1 4.1 14.7 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF4446 PF14584.1 CDI86868.1 - 8.2 6.2 10.7 11 5.8 7.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) HemX PF04375.9 CDI86868.1 - 8.3 4.8 40.1 9.6 4.6 27.8 1.0 1 0 0 1 1 1 0 HemX Peptidase_S15 PF02129.13 CDI86868.1 - 8.4 5.7 20.0 9.7 5.5 13.9 1.1 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) AUX_IAA PF02309.11 CDI86868.1 - 9.6 5.8 18.4 11 5.6 12.8 1.2 1 0 0 1 1 1 0 AUX/IAA family Hid1 PF12722.2 CDI86869.1 - 0.00018 19.3 26.8 0.00023 19.0 18.5 1.1 1 0 0 1 1 1 1 High-temperature-induced dauer-formation protein Herpes_UL87 PF03043.9 CDI86869.1 - 0.00035 19.0 0.4 0.00035 19.0 0.3 2.0 1 1 1 2 2 2 1 Herpesvirus UL87 family DUF1510 PF07423.6 CDI86869.1 - 0.0014 18.0 18.4 0.0014 18.0 12.7 4.8 2 2 1 3 3 3 1 Protein of unknown function (DUF1510) Med15 PF09606.5 CDI86869.1 - 1.6 6.8 117.3 2 6.4 81.3 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal PMSI1 PF15322.1 CDI86869.1 - 4.1 6.4 33.9 6.3 5.7 23.5 1.3 1 0 0 1 1 1 0 Protein missing in infertile sperm 1, putative Utp14 PF04615.8 CDI86869.1 - 6.5 4.7 54.2 8 4.4 37.5 1.0 1 0 0 1 1 1 0 Utp14 protein SOBP PF15279.1 CDI86869.1 - 9.8 6.4 37.8 13 6.0 26.2 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein Claudin_2 PF13903.1 CDI86870.1 - 0.0061 16.2 5.5 0.0061 16.2 3.8 2.2 2 0 0 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction DUF898 PF05987.8 CDI86870.1 - 0.043 12.7 0.3 0.06 12.2 0.2 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF898) SprA-related PF12118.3 CDI86870.1 - 0.053 12.8 44.7 0.078 12.2 31.0 1.2 1 0 0 1 1 1 0 SprA-related family Med15 PF09606.5 CDI86870.1 - 0.066 11.4 57.3 0.081 11.1 39.7 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal FLO_LFY PF01698.11 CDI86870.1 - 0.16 10.7 14.3 0.2 10.4 9.9 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein GAGA_bind PF06217.7 CDI86870.1 - 0.65 9.8 19.9 0.77 9.6 13.8 1.0 1 0 0 1 1 1 0 GAGA binding protein-like family AAA_23 PF13476.1 CDI86870.1 - 0.82 9.9 18.3 1 9.6 12.7 1.1 1 0 0 1 1 1 0 AAA domain Hid1 PF12722.2 CDI86870.1 - 0.92 7.1 13.9 0.95 7.0 9.6 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF2215 PF10225.4 CDI86870.1 - 0.95 8.8 10.4 1.3 8.4 7.2 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) Ycf1 PF05758.7 CDI86870.1 - 1.1 6.8 15.0 1.2 6.7 10.4 1.0 1 0 0 1 1 1 0 Ycf1 Tetraspannin PF00335.15 CDI86870.1 - 1.1 8.4 3.5 1.6 7.9 2.5 1.3 1 0 0 1 1 1 0 Tetraspanin family SID-1_RNA_chan PF13965.1 CDI86870.1 - 1.5 6.9 9.1 1.7 6.6 6.3 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Dynamin_N PF00350.18 CDI86870.1 - 1.6 8.5 10.5 2.4 7.9 7.3 1.3 1 0 0 1 1 1 0 Dynamin family DUF4446 PF14584.1 CDI86870.1 - 1.6 8.5 8.2 2.6 7.8 5.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) PAT1 PF09770.4 CDI86870.1 - 1.7 6.8 46.6 1.9 6.6 32.3 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Rtt102p PF09510.5 CDI86870.1 - 1.7 8.6 9.1 2.8 7.9 6.3 1.3 1 0 0 1 1 1 0 Rtt102p-like transcription regulator protein DUF4367 PF14285.1 CDI86870.1 - 2.1 7.6 12.8 0.02 14.1 1.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4367) Nucleoside_tran PF01733.13 CDI86870.1 - 2.2 7.3 4.6 2.9 6.9 3.2 1.1 1 0 0 1 1 1 0 Nucleoside transporter eIF-3_zeta PF05091.7 CDI86870.1 - 2.3 6.7 21.0 2.6 6.5 14.5 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Ctr PF04145.10 CDI86870.1 - 3.1 7.8 14.3 3.5 7.6 8.8 1.9 1 1 1 2 2 2 0 Ctr copper transporter family Lig_chan PF00060.21 CDI86870.1 - 3.3 7.4 14.4 7.1 6.3 10.0 1.6 1 1 0 1 1 1 0 Ligand-gated ion channel Peptidase_U57 PF05582.7 CDI86870.1 - 4.2 6.2 12.5 5.9 5.7 8.7 1.2 1 0 0 1 1 1 0 YabG peptidase U57 Peptidase_S15 PF02129.13 CDI86870.1 - 4.6 6.5 17.1 6.2 6.1 11.8 1.3 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) MRP-S31 PF15433.1 CDI86870.1 - 7.7 5.8 22.8 9.7 5.5 15.8 1.2 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 YABBY PF04690.8 CDI86870.1 - 9.7 6.3 17.9 0.14 12.4 6.6 1.9 2 0 0 2 2 2 0 YABBY protein Ribosomal_60s PF00428.14 CDI86871.1 - 0.037 14.4 7.1 0.037 14.4 4.9 1.8 2 0 0 2 2 2 0 60s Acidic ribosomal protein Activator_LAG-3 PF11498.3 CDI86871.1 - 0.097 11.4 28.4 0.13 11.0 19.7 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Usp PF00582.21 CDI86871.1 - 0.16 12.1 1.4 0.26 11.4 0.9 1.3 1 0 0 1 1 1 0 Universal stress protein family LIM_bind PF01803.11 CDI86871.1 - 0.82 8.7 8.4 1.3 8.1 5.8 1.2 1 0 0 1 1 1 0 LIM-domain binding protein PAT1 PF09770.4 CDI86871.1 - 1.3 7.2 33.2 1.5 6.9 23.0 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF3464 PF11947.3 CDI86871.1 - 2.8 7.3 5.9 5.2 6.5 4.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) TFIIA PF03153.8 CDI86871.1 - 7.1 6.4 21.2 9 6.0 14.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PAT1 PF09770.4 CDI86872.1 - 0.59 8.3 58.0 0.77 7.9 40.2 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 MIP-T3 PF10243.4 CDI86872.1 - 3.9 5.8 46.9 6.4 5.1 32.5 1.3 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Med15 PF09606.5 CDI86874.1 - 0.0016 16.7 27.9 0.0019 16.4 19.3 1.1 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal BAF1_ABF1 PF04684.8 CDI86874.1 - 0.002 17.0 24.0 0.0028 16.5 16.7 1.1 1 0 0 1 1 1 1 BAF1 / ABF1 chromatin reorganising factor Suf PF05843.9 CDI86874.1 - 0.045 13.4 5.0 0.048 13.3 3.4 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) FLO_LFY PF01698.11 CDI86874.1 - 0.046 12.5 7.8 0.055 12.3 5.4 1.2 1 0 0 1 1 1 0 Floricaula / Leafy protein CDK2AP PF09806.4 CDI86874.1 - 0.071 13.3 19.3 0.1 12.8 13.4 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein PAT1 PF09770.4 CDI86874.1 - 0.11 10.7 20.2 0.12 10.5 14.0 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Activator_LAG-3 PF11498.3 CDI86874.1 - 0.19 10.4 25.7 0.23 10.1 17.8 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 CDC45 PF02724.9 CDI86874.1 - 0.22 9.5 12.8 0.27 9.2 8.9 1.0 1 0 0 1 1 1 0 CDC45-like protein DUF4647 PF15504.1 CDI86874.1 - 0.26 10.1 12.4 0.38 9.5 8.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4647) DUF2413 PF10310.4 CDI86874.1 - 0.3 9.8 18.2 0.39 9.4 12.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) DUF3138 PF11336.3 CDI86874.1 - 0.31 9.1 12.1 0.39 8.8 8.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Sporozoite_P67 PF05642.6 CDI86874.1 - 0.33 8.7 10.0 0.4 8.4 7.0 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Band_3_cyto PF07565.8 CDI86874.1 - 0.34 10.3 6.4 0.45 9.9 4.4 1.3 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Herpes_TAF50 PF03326.8 CDI86874.1 - 0.36 9.7 15.7 0.45 9.3 10.9 1.1 1 0 0 1 1 1 0 Herpesvirus transcription activation factor (transactivator) AAA_23 PF13476.1 CDI86874.1 - 0.47 10.7 10.5 0.59 10.4 7.3 1.2 1 0 0 1 1 1 0 AAA domain RR_TM4-6 PF06459.7 CDI86874.1 - 0.61 9.9 10.7 0.77 9.5 7.4 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SpoIIE PF07228.7 CDI86874.1 - 0.74 9.4 3.5 0.22 11.2 0.2 1.6 2 0 0 2 2 2 0 Stage II sporulation protein E (SpoIIE) Spt20 PF12090.3 CDI86874.1 - 0.78 9.0 9.8 1.2 8.4 6.8 1.3 1 0 0 1 1 1 0 Spt20 family Mitofilin PF09731.4 CDI86874.1 - 0.86 8.1 17.8 1.1 7.8 12.4 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein UPF0560 PF10577.4 CDI86874.1 - 0.89 7.7 17.2 1.2 7.3 12.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 DUF4175 PF13779.1 CDI86874.1 - 1 6.9 33.5 1.3 6.6 23.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Plasmodium_Vir PF05795.6 CDI86874.1 - 1.1 8.4 5.3 1.3 8.1 3.7 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein NST1 PF13945.1 CDI86874.1 - 1.2 9.1 18.3 1.5 8.8 12.7 1.2 1 0 0 1 1 1 0 Salt tolerance down-regulator FAM60A PF15396.1 CDI86874.1 - 1.6 8.4 7.9 2.2 7.9 5.5 1.2 1 0 0 1 1 1 0 Protein Family FAM60A DNA_pol_viral_N PF00242.12 CDI86874.1 - 1.7 7.6 14.1 2.2 7.2 9.8 1.1 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain DUF966 PF06136.8 CDI86874.1 - 2 7.7 14.2 2.6 7.3 9.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Serinc PF03348.10 CDI86874.1 - 2.4 6.7 8.6 3 6.4 5.9 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) VID27 PF08553.5 CDI86874.1 - 2.7 6.0 13.7 3.4 5.7 9.5 1.1 1 0 0 1 1 1 0 VID27 cytoplasmic protein FAM176 PF14851.1 CDI86874.1 - 2.7 7.6 7.3 3.9 7.1 5.1 1.2 1 0 0 1 1 1 0 FAM176 family Hid1 PF12722.2 CDI86874.1 - 2.8 5.5 14.0 3.3 5.2 9.7 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Dicty_REP PF05086.7 CDI86874.1 - 2.8 5.6 5.7 3 5.4 4.0 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein SbcCD_C PF13558.1 CDI86874.1 - 2.9 7.8 8.3 7 6.6 5.8 1.7 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit SpaB_C PF14028.1 CDI86874.1 - 2.9 7.3 8.7 3.5 7.0 6.0 1.1 1 0 0 1 1 1 0 SpaB C-terminal domain Ctr PF04145.10 CDI86874.1 - 3.8 7.5 6.3 5.5 7.0 4.4 1.3 1 0 0 1 1 1 0 Ctr copper transporter family Ycf1 PF05758.7 CDI86874.1 - 3.9 5.0 9.5 4.4 4.9 6.6 1.0 1 0 0 1 1 1 0 Ycf1 DUF2201_N PF13203.1 CDI86874.1 - 4 6.5 19.2 6.1 5.9 13.3 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain CDK5_activator PF03261.10 CDI86874.1 - 4 6.6 12.2 5.2 6.3 8.5 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein PIH1 PF08190.7 CDI86874.1 - 4.4 6.6 14.4 5.9 6.2 10.0 1.2 1 0 0 1 1 1 0 pre-RNA processing PIH1/Nop17 Paf1 PF03985.8 CDI86874.1 - 4.6 5.8 15.8 6.9 5.2 10.9 1.2 1 0 0 1 1 1 0 Paf1 Ndc1_Nup PF09531.5 CDI86874.1 - 5.2 5.3 10.4 6.2 5.1 7.2 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF2217 PF10265.4 CDI86874.1 - 6.3 5.4 8.7 7.9 5.1 6.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) Macoilin PF09726.4 CDI86874.1 - 6.9 4.8 12.6 8.5 4.5 8.7 1.1 1 0 0 1 1 1 0 Transmembrane protein Neur_chan_memb PF02932.11 CDI86874.1 - 6.9 6.4 11.5 9 6.0 8.0 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Vfa1 PF08432.5 CDI86874.1 - 7 6.6 15.7 9.8 6.1 10.8 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 CDC73 PF05179.9 CDI86874.1 - 8.1 5.7 12.6 11 5.2 8.7 1.1 1 0 0 1 1 1 0 RNA pol II accessory factor, Cdc73 family Pex16 PF08610.5 CDI86874.1 - 8.8 5.2 8.4 11 4.8 5.8 1.1 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) PAS PF00989.19 CDI86874.1 - 9.6 6.0 7.5 23 4.7 5.2 1.6 1 0 0 1 1 1 0 PAS fold DUF3487 PF11990.3 CDI86875.1 - 0.0068 15.8 0.1 0.013 14.8 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3487) NTP_transf_3 PF12804.2 CDI86875.1 - 0.096 12.7 3.8 0.094 12.7 1.7 1.6 2 0 0 2 2 2 0 MobA-like NTP transferase domain DUF2217 PF10265.4 CDI86875.1 - 0.37 9.4 30.6 0.5 9.0 21.2 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) Med15 PF09606.5 CDI86875.1 - 1.3 7.1 86.4 1.4 7.0 59.9 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Herpes_BLLF1 PF05109.8 CDI86875.1 - 8.6 4.1 28.5 11 3.8 19.8 1.1 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) RRM_1 PF00076.17 CDI86876.1 - 8.6e-11 41.3 0.1 1.6e-06 27.6 0.0 2.4 1 1 1 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CDI86876.1 - 2.9e-06 27.1 0.0 0.0018 18.2 0.0 2.3 1 1 1 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF3365 PF11845.3 CDI86876.1 - 0.61 9.9 12.2 1.8 8.3 8.5 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3365) UDPG_MGDP_dh_C PF03720.10 CDI86876.1 - 1.2 9.2 4.0 75 3.5 2.8 2.4 1 1 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain SURF2 PF05477.6 CDI86876.1 - 2.5 7.1 16.3 3.7 6.5 11.3 1.2 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) CNP1 PF08750.6 CDI86876.1 - 4.4 6.9 12.7 2.2 7.9 1.4 2.7 2 1 1 3 3 3 0 CNP1-like family GPCR_chapero_1 PF11904.3 CDI86876.1 - 5.3 6.0 13.9 7.5 5.5 9.6 1.3 1 0 0 1 1 1 0 GPCR-chaperone ATP-sulfurylase PF01747.12 CDI86877.1 - 1.5e-62 210.7 0.0 2.4e-62 210.0 0.0 1.3 1 0 0 1 1 1 1 ATP-sulfurylase APS_kinase PF01583.15 CDI86877.1 - 2.8e-51 173.2 0.0 6.9e-51 172.0 0.0 1.7 1 1 0 1 1 1 1 Adenylylsulphate kinase PUA_2 PF14306.1 CDI86877.1 - 1.6e-31 108.8 0.0 1.4e-30 105.8 0.0 2.1 1 1 0 1 1 1 1 PUA-like domain AAA_33 PF13671.1 CDI86877.1 - 2.1e-09 37.3 0.0 5.5e-09 36.0 0.0 1.7 2 0 0 2 2 2 1 AAA domain KTI12 PF08433.5 CDI86877.1 - 5.9e-05 22.4 0.0 0.00012 21.3 0.0 1.5 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_17 PF13207.1 CDI86877.1 - 8.9e-05 23.3 0.0 0.0004 21.2 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 CDI86877.1 - 0.00032 20.9 0.1 0.00081 19.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.1 CDI86877.1 - 0.0024 17.8 0.0 0.0047 16.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 CDI86877.1 - 0.018 15.0 0.0 0.033 14.1 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain MMR_HSR1 PF01926.18 CDI86877.1 - 0.055 13.4 0.0 0.13 12.2 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase ECSIT PF06239.6 CDI86877.1 - 0.074 11.9 0.1 0.13 11.1 0.0 1.3 1 0 0 1 1 1 0 Evolutionarily conserved signalling intermediate in Toll pathway Spore_YhaL PF14147.1 CDI86877.1 - 0.096 12.1 0.0 0.2 11.1 0.0 1.5 1 0 0 1 1 1 0 Sporulation protein YhaL ArgK PF03308.11 CDI86877.1 - 0.13 10.9 0.0 0.23 10.1 0.0 1.3 1 0 0 1 1 1 0 ArgK protein CIAPIN1 PF05093.8 CDI86878.1 - 1.6e-24 85.8 13.6 8.2e-24 83.5 9.4 2.0 1 1 0 1 1 1 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis K_channel_TID PF07941.6 CDI86878.1 - 0.017 15.3 20.7 0.3 11.3 3.2 2.5 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain Shadoo PF14999.1 CDI86878.1 - 0.66 9.8 21.1 0.53 10.1 5.7 2.4 2 0 0 2 2 2 0 Shadow of prion protein, neuroprotective Ribosomal_60s PF00428.14 CDI86878.1 - 5.3 7.5 31.5 2.3 8.6 7.7 3.0 3 0 0 3 3 3 0 60s Acidic ribosomal protein SR-25 PF10500.4 CDI86879.1 - 0.00023 20.7 7.3 0.00036 20.0 5.1 1.3 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein FAM60A PF15396.1 CDI86879.1 - 0.0029 17.3 1.0 0.0041 16.8 0.7 1.1 1 0 0 1 1 1 1 Protein Family FAM60A Rab_eff_C PF04698.7 CDI86879.1 - 0.011 13.9 4.9 0.013 13.6 3.4 1.1 1 0 0 1 1 1 0 Rab effector MyRIP/melanophilin C-terminus RNA_pol_Rpc4 PF05132.9 CDI86879.1 - 0.031 14.2 0.5 0.052 13.5 0.3 1.5 1 0 0 1 1 1 0 RNA polymerase III RPC4 Pex14_N PF04695.8 CDI86879.1 - 0.37 10.8 9.5 0.92 9.5 6.6 1.8 1 1 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Period_C PF12114.3 CDI86879.1 - 0.39 10.2 13.5 0.67 9.5 9.4 1.3 1 0 0 1 1 1 0 Period protein 2/3C-terminal region Macoilin PF09726.4 CDI86879.1 - 0.74 8.0 8.9 1.1 7.5 6.2 1.2 1 0 0 1 1 1 0 Transmembrane protein Bul1_N PF04425.7 CDI86879.1 - 1 7.8 6.0 1.5 7.2 4.2 1.2 1 0 0 1 1 1 0 Bul1 N terminus AF-4 PF05110.8 CDI86879.1 - 1.1 7.0 13.6 1.4 6.7 9.5 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Apt1 PF10351.4 CDI86879.1 - 6.8 5.4 10.1 9.9 4.8 7.0 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF576 PF04507.7 CDI86881.1 - 0.015 14.2 0.5 0.017 14.0 0.3 1.0 1 0 0 1 1 1 0 Protein of unknown function, DUF576 RAB3GAP2_N PF14655.1 CDI86881.1 - 0.017 14.1 7.3 0.02 13.8 5.0 1.0 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus CAMSAP_CKK PF08683.6 CDI86881.1 - 0.12 12.0 2.3 0.14 11.8 1.6 1.0 1 0 0 1 1 1 0 Microtubule-binding calmodulin-regulated spectrin-associated PH_4 PF15404.1 CDI86881.1 - 0.15 11.5 4.4 0.17 11.3 3.0 1.1 1 0 0 1 1 1 0 Pleckstrin homology domain NAD_binding_9 PF13454.1 CDI86881.1 - 0.32 10.7 3.5 0.38 10.5 2.4 1.1 1 0 0 1 1 1 0 FAD-NAD(P)-binding DUF4446 PF14584.1 CDI86881.1 - 1.7 8.4 7.7 2 8.2 5.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) DUF1151 PF06625.6 CDI86881.1 - 2.3 7.9 16.4 3.2 7.5 11.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1151) Peptidase_S30 PF01577.11 CDI86881.1 - 2.7 7.3 8.6 3.1 7.1 5.9 1.0 1 0 0 1 1 1 0 Potyvirus P1 protease RRN9 PF10680.4 CDI86881.1 - 3.7 7.3 5.4 1.9 8.2 2.5 1.5 1 1 1 2 2 2 0 RNA polymerase I specific transcription initiation factor DUF1525 PF07511.6 CDI86881.1 - 3.8 7.5 13.8 4.4 7.3 9.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1525) Band_3_cyto PF07565.8 CDI86881.1 - 4.3 6.7 9.7 4.6 6.6 6.7 1.0 1 0 0 1 1 1 0 Band 3 cytoplasmic domain DUF3533 PF12051.3 CDI86881.1 - 4.5 5.9 8.0 5 5.7 5.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3533) FAA_hydrolase_N PF09298.6 CDI86881.1 - 5.2 7.1 9.2 6.2 6.8 6.4 1.1 1 0 0 1 1 1 0 Fumarylacetoacetase N-terminal Peptidase_C58 PF03543.9 CDI86881.1 - 5.8 6.3 14.5 6.9 6.1 10.0 1.1 1 0 0 1 1 1 0 Yersinia/Haemophilus virulence surface antigen Tim54 PF11711.3 CDI86882.1 - 0.014 14.0 3.8 0.014 13.9 2.6 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 TMEM51 PF15345.1 CDI86882.1 - 0.019 14.6 7.4 0.025 14.2 5.1 1.2 1 0 0 1 1 1 0 Transmembrane protein 51 RR_TM4-6 PF06459.7 CDI86882.1 - 0.04 13.8 9.4 0.047 13.5 6.5 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Ycf1 PF05758.7 CDI86882.1 - 0.042 11.5 9.7 0.051 11.2 6.7 1.0 1 0 0 1 1 1 0 Ycf1 SID-1_RNA_chan PF13965.1 CDI86882.1 - 0.046 11.9 4.5 0.057 11.5 3.1 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DUF1510 PF07423.6 CDI86882.1 - 0.049 13.0 12.7 0.064 12.6 8.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) TFIIA PF03153.8 CDI86882.1 - 0.056 13.3 17.9 0.067 13.0 12.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Anoctamin PF04547.7 CDI86882.1 - 0.066 11.8 1.0 0.054 12.1 0.7 1.1 1 0 0 1 1 1 0 Calcium-activated chloride channel PAT1 PF09770.4 CDI86882.1 - 0.069 11.3 22.8 0.071 11.3 15.8 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 CobT PF06213.7 CDI86882.1 - 0.074 12.1 8.7 0.089 11.9 6.0 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Ctr PF04145.10 CDI86882.1 - 0.075 13.0 4.2 0.16 12.0 2.9 1.6 1 0 0 1 1 1 0 Ctr copper transporter family SpoIIP PF07454.6 CDI86882.1 - 0.079 12.1 8.9 0.098 11.8 6.2 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Zip PF02535.17 CDI86882.1 - 0.086 11.8 2.6 0.1 11.6 1.8 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter DDHD PF02862.12 CDI86882.1 - 0.091 12.5 9.8 0.11 12.3 6.8 1.1 1 0 0 1 1 1 0 DDHD domain SprA-related PF12118.3 CDI86882.1 - 0.1 11.9 25.5 0.13 11.6 17.7 1.2 1 0 0 1 1 1 0 SprA-related family FLO_LFY PF01698.11 CDI86882.1 - 0.11 11.2 9.6 0.13 11.0 6.7 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein Peptidase_S49_N PF08496.5 CDI86882.1 - 0.12 12.1 9.1 0.16 11.7 6.3 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal TRAP_alpha PF03896.11 CDI86882.1 - 0.13 11.2 5.3 0.23 10.4 3.7 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit EIIBC-GUT_N PF03612.9 CDI86882.1 - 0.13 11.8 6.0 0.18 11.4 4.1 1.2 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus AIF_C PF14721.1 CDI86882.1 - 0.14 12.4 8.9 0.2 11.8 6.2 1.3 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term PBP_sp32 PF07222.7 CDI86882.1 - 0.23 10.6 17.2 0.29 10.2 11.9 1.2 1 0 0 1 1 1 0 Proacrosin binding protein sp32 DUF2828 PF11443.3 CDI86882.1 - 0.26 9.4 6.5 0.29 9.2 4.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Rhabdo_ncap PF00945.13 CDI86882.1 - 0.36 9.3 5.3 0.47 8.9 3.7 1.1 1 0 0 1 1 1 0 Rhabdovirus nucleocapsid protein DUF4045 PF13254.1 CDI86882.1 - 0.45 9.7 8.8 0.51 9.5 6.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) eIF-3_zeta PF05091.7 CDI86882.1 - 0.46 9.0 11.6 0.48 8.9 8.0 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Peptidase_S15 PF02129.13 CDI86882.1 - 0.49 9.7 7.7 0.62 9.4 5.3 1.1 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Hid1 PF12722.2 CDI86882.1 - 0.57 7.7 10.6 0.65 7.6 7.3 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Activator_LAG-3 PF11498.3 CDI86882.1 - 0.66 8.6 34.9 0.81 8.3 24.2 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 FAM91_C PF14648.1 CDI86882.1 - 0.8 8.4 6.7 0.97 8.2 4.6 1.0 1 0 0 1 1 1 0 FAM91 C-terminus DUF4557 PF15101.1 CDI86882.1 - 0.93 9.2 19.3 1.2 8.9 13.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) Med15 PF09606.5 CDI86882.1 - 0.94 7.5 35.5 1 7.4 24.6 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal SHR3_chaperone PF08229.6 CDI86882.1 - 1 8.2 11.7 1.6 7.6 8.1 1.3 1 0 0 1 1 1 0 ER membrane protein SH3 Presenilin PF01080.12 CDI86882.1 - 1.1 8.0 4.8 1.2 7.9 3.3 1.1 1 0 0 1 1 1 0 Presenilin Serinc PF03348.10 CDI86882.1 - 1.1 7.9 15.6 0.021 13.5 6.1 1.5 2 0 0 2 2 2 0 Serine incorporator (Serinc) Baculo_PP31 PF05311.6 CDI86882.1 - 1.1 8.4 10.2 1.3 8.2 7.1 1.1 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) Folate_carrier PF01770.13 CDI86882.1 - 1.2 7.5 6.0 1.5 7.2 4.1 1.2 1 0 0 1 1 1 0 Reduced folate carrier Dynamin_N PF00350.18 CDI86882.1 - 1.5 8.6 6.4 1.8 8.3 4.4 1.1 1 0 0 1 1 1 0 Dynamin family MMR1 PF08505.5 CDI86882.1 - 1.9 8.4 15.7 2.4 8.1 10.9 1.1 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein HemX PF04375.9 CDI86882.1 - 2 6.9 22.1 2.4 6.6 15.3 1.1 1 0 0 1 1 1 0 HemX FAM176 PF14851.1 CDI86882.1 - 2.3 7.9 7.5 3.7 7.2 5.2 1.4 1 0 0 1 1 1 0 FAM176 family YABBY PF04690.8 CDI86882.1 - 2.5 8.3 8.5 3.1 7.9 5.9 1.2 1 0 0 1 1 1 0 YABBY protein DUF808 PF05661.7 CDI86882.1 - 2.5 6.8 4.0 3.4 6.4 2.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF808) Mem_trans PF03547.13 CDI86882.1 - 3.3 5.9 5.7 4.3 5.5 3.9 1.2 1 0 0 1 1 1 0 Membrane transport protein Band_3_cyto PF07565.8 CDI86882.1 - 3.5 7.0 14.8 4.6 6.6 10.2 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain DUF4446 PF14584.1 CDI86882.1 - 3.6 7.4 7.3 5.9 6.7 5.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) DUF4175 PF13779.1 CDI86882.1 - 3.9 5.0 36.7 5.2 4.6 25.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Hom_end_hint PF05203.11 CDI86882.1 - 4.2 7.0 9.9 5.2 6.7 6.8 1.1 1 0 0 1 1 1 0 Hom_end-associated Hint OATP PF03137.15 CDI86882.1 - 4.5 5.2 9.7 5.5 4.9 6.7 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Paramyxo_ncap PF00973.14 CDI86882.1 - 5.6 5.5 8.8 6.3 5.3 6.1 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein DUF1682 PF07946.9 CDI86882.1 - 7 5.3 17.7 10 4.8 12.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) RED_N PF07808.8 CDI86882.1 - 8.3 5.5 22.0 11 5.0 15.2 1.1 1 0 0 1 1 1 0 RED-like protein N-terminal region Med15 PF09606.5 CDI86883.1 - 0.0019 16.5 63.0 0.0019 16.4 43.7 1.1 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal DUF1628 PF07790.6 CDI86883.1 - 0.85 10.4 0.1 0.85 10.4 0.1 3.7 3 1 0 3 3 3 0 Protein of unknown function (DUF1628) Utp14 PF04615.8 CDI86883.1 - 9.1 4.3 39.1 13 3.8 27.1 1.2 1 0 0 1 1 1 0 Utp14 protein UPF0240 PF06784.6 CDI86884.1 - 0.094 12.3 3.7 0.15 11.7 2.6 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0240) PAT1 PF09770.4 CDI86884.1 - 2.6 6.1 20.4 3.5 5.7 14.1 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Phostensin_N PF13916.1 CDI86884.1 - 3.6 7.6 20.1 0.51 10.3 3.4 2.5 1 1 1 2 2 2 0 PP1-regulatory protein, Phostensin N-terminal SOBP PF15279.1 CDI86885.1 - 0.057 13.7 12.8 0.07 13.5 8.9 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein DUF4647 PF15504.1 CDI86885.1 - 0.059 12.2 11.8 0.089 11.6 8.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4647) CAF-1_p150 PF11600.3 CDI86885.1 - 0.14 11.5 22.7 0.21 10.9 15.7 1.3 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal PPP4R2 PF09184.6 CDI86885.1 - 0.22 11.0 17.3 0.3 10.6 12.0 1.2 1 0 0 1 1 1 0 PPP4R2 SR-25 PF10500.4 CDI86885.1 - 0.31 10.4 29.6 0.3 10.5 9.3 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Utp14 PF04615.8 CDI86885.1 - 0.65 8.1 23.6 0.038 12.1 13.1 1.3 2 0 0 2 2 2 0 Utp14 protein AAA_23 PF13476.1 CDI86885.1 - 0.9 9.8 8.4 1.4 9.2 5.9 1.3 1 0 0 1 1 1 0 AAA domain Hid1 PF12722.2 CDI86885.1 - 1 6.9 15.2 1.2 6.7 10.5 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Ebola_NP PF05505.7 CDI86885.1 - 1.5 6.8 13.3 1.9 6.4 9.2 1.1 1 0 0 1 1 1 0 Ebola nucleoprotein DUF4175 PF13779.1 CDI86885.1 - 3.2 5.3 35.5 5.1 4.6 24.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) TFIIA PF03153.8 CDI86885.1 - 5.1 6.8 27.4 6.9 6.4 19.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit BTV_NS2 PF04514.7 CDI86885.1 - 5.2 5.8 17.1 6.8 5.4 11.9 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Parvo_coat PF00740.13 CDI86885.1 - 5.5 5.8 13.6 6.4 5.6 9.4 1.1 1 0 0 1 1 1 0 Parvovirus coat protein VP2 Spt20 PF12090.3 CDI86887.1 - 0.0016 17.8 8.8 0.47 9.7 0.3 3.3 3 0 0 3 3 3 3 Spt20 family Peroxin-13_N PF04088.8 CDI86887.1 - 0.28 11.1 2.7 13 5.7 0.0 3.7 4 0 0 4 4 4 0 Peroxin 13, N-terminal region Ribosomal_60s PF00428.14 CDI86887.1 - 0.3 11.4 8.2 0.05 14.0 2.8 1.8 2 0 0 2 2 2 0 60s Acidic ribosomal protein Suf PF05843.9 CDI86887.1 - 1.9 8.1 15.2 6.3 6.4 0.4 3.3 3 0 0 3 3 3 0 Suppressor of forked protein (Suf) Ribosomal_60s PF00428.14 CDI86888.1 - 0.011 16.1 12.4 0.011 16.1 8.6 4.2 3 1 0 3 3 3 0 60s Acidic ribosomal protein RAB3GAP2_N PF14655.1 CDI86888.1 - 9.1 5.1 15.6 4.1 6.3 4.7 2.6 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus IncA PF04156.9 CDI86889.1 - 1.2e-05 25.0 5.9 1.2e-05 25.0 4.1 4.6 5 0 0 5 5 2 2 IncA protein BAF1_ABF1 PF04684.8 CDI86889.1 - 0.00087 18.2 8.9 0.00087 18.2 6.2 9.1 7 3 1 9 9 4 1 BAF1 / ABF1 chromatin reorganising factor zf-DHHC PF01529.15 CDI86889.1 - 0.022 14.1 1.2 0.9 8.9 0.4 2.2 2 0 0 2 2 2 0 DHHC palmitoyltransferase FimP PF09766.4 CDI86889.1 - 0.05 12.6 29.8 0.095 11.7 1.9 2.3 2 0 0 2 2 2 0 Fms-interacting protein Spt20 PF12090.3 CDI86889.1 - 0.067 12.5 13.3 0.61 9.4 0.3 2.6 2 0 0 2 2 2 0 Spt20 family Potyvirid-P3 PF13608.1 CDI86889.1 - 0.38 9.8 14.1 0.17 10.9 0.6 2.1 2 0 0 2 2 2 0 Protein P3 of Potyviral polyprotein DUF4647 PF15504.1 CDI86889.1 - 0.42 9.4 22.3 0.036 12.9 6.8 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4647) AAA_23 PF13476.1 CDI86889.1 - 0.6 10.4 12.9 0.38 11.0 1.7 2.2 2 0 0 2 2 2 0 AAA domain Neur_chan_memb PF02932.11 CDI86889.1 - 0.84 9.4 9.6 0.62 9.9 1.5 2.4 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Peptidase_S49_N PF08496.5 CDI86889.1 - 0.9 9.3 10.0 0.43 10.3 1.9 2.6 2 0 0 2 2 2 0 Peptidase family S49 N-terminal DDHD PF02862.12 CDI86889.1 - 2.1 8.0 18.0 3 7.5 4.4 2.7 2 0 0 2 2 2 0 DDHD domain eIF-3_zeta PF05091.7 CDI86889.1 - 4.7 5.7 21.1 1.9 7.0 6.8 2.1 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Otopetrin PF03189.8 CDI86889.1 - 6.7 5.5 7.7 1.3 7.9 0.4 2.1 2 0 0 2 2 2 0 Otopetrin WD40 PF00400.27 CDI86892.1 - 1.5e-16 59.5 10.5 8.5e-05 22.2 0.1 5.6 5 0 0 5 5 5 4 WD domain, G-beta repeat Peptidase_M20 PF01546.23 CDI86892.1 - 9.8e-11 41.4 0.0 0.00049 19.6 0.0 4.0 3 1 0 3 3 3 2 Peptidase family M20/M25/M40 GATase_6 PF13522.1 CDI86892.1 - 4.8e-05 23.3 0.0 0.001 19.0 0.0 2.5 1 1 1 2 2 2 1 Glutamine amidotransferase domain M20_dimer PF07687.9 CDI86892.1 - 9.1e-05 22.1 0.0 0.00025 20.7 0.0 1.7 1 0 0 1 1 1 1 Peptidase dimerisation domain CKS PF01111.14 CDI86893.1 - 1e-17 63.6 0.0 2.4e-17 62.4 0.0 1.7 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit CutC PF03932.9 CDI86895.1 - 0.026 13.7 0.0 0.046 12.9 0.0 1.3 1 0 0 1 1 1 0 CutC family DUF4164 PF13747.1 CDI86895.1 - 1.3 9.2 11.2 0.17 11.9 1.2 3.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4164) DUF4510 PF14971.1 CDI86895.1 - 3.6 7.7 8.9 2.1 8.4 2.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4510) Med4 PF10018.4 CDI86895.1 - 6.7 6.0 8.7 0.23 10.8 0.6 2.3 3 0 0 3 3 3 0 Vitamin-D-receptor interacting Mediator subunit 4 ACDC PF14733.1 CDI86896.1 - 4.2e-05 23.5 0.1 0.0027 17.7 0.1 2.3 2 0 0 2 2 2 1 AP2-coincident C-terminal Spt20 PF12090.3 CDI86896.1 - 2.6 7.3 40.1 1.7 7.9 1.6 5.2 5 0 0 5 5 5 0 Spt20 family Trypan_PARP PF05887.6 CDI86898.1 - 0.0089 15.8 8.4 0.0089 15.8 5.8 2.0 2 1 0 2 2 2 1 Procyclic acidic repetitive protein (PARP) AMPKBI PF04739.10 CDI86898.1 - 0.025 14.4 6.5 0.048 13.5 4.5 1.4 1 0 0 1 1 1 0 5'-AMP-activated protein kinase beta subunit, interation domain DUF1510 PF07423.6 CDI86898.1 - 2.7 7.2 31.2 0.46 9.8 10.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) U79_P34 PF03064.11 CDI86898.1 - 7.2 6.0 29.1 0.5 9.8 12.5 2.1 2 0 0 2 2 2 0 HSV U79 / HCMV P34 MIP-T3 PF10243.4 CDI86900.1 - 2.5 6.4 73.0 2.9 6.2 50.6 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Trypan_PARP PF05887.6 CDI86900.1 - 5 6.9 78.7 4 7.2 20.6 3.0 1 1 2 3 3 3 0 Procyclic acidic repetitive protein (PARP) ATP12 PF07542.6 CDI86901.1 - 4.3e-05 23.4 8.9 4.3e-05 23.4 6.2 3.9 2 2 0 2 2 2 1 ATP12 chaperone protein AAA_23 PF13476.1 CDI86901.1 - 0.051 13.8 20.9 0.21 11.9 7.9 2.2 2 0 0 2 2 2 0 AAA domain SR-25 PF10500.4 CDI86902.1 - 3.5e-05 23.3 39.7 4.7e-05 22.9 22.4 2.4 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein SprA-related PF12118.3 CDI86902.1 - 0.0003 20.2 49.1 0.0003 20.2 34.0 2.4 2 1 0 2 2 1 1 SprA-related family DUF1510 PF07423.6 CDI86902.1 - 0.0092 15.3 29.3 0.11 11.9 18.2 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1510) MelC1 PF06236.6 CDI86902.1 - 0.073 13.0 0.3 0.073 13.0 0.2 2.5 2 1 0 2 2 1 0 Tyrosinase co-factor MelC1 FimP PF09766.4 CDI86902.1 - 0.076 12.0 0.1 0.076 12.0 0.1 3.1 2 1 1 3 3 1 0 Fms-interacting protein Med15 PF09606.5 CDI86902.1 - 0.26 9.4 94.0 0.015 13.5 3.5 2.1 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal GAGA_bind PF06217.7 CDI86902.1 - 0.57 10.0 30.2 5.1 6.9 19.1 2.0 2 0 0 2 2 2 0 GAGA binding protein-like family Corona_nucleoca PF00937.13 CDI86902.1 - 0.63 8.9 38.7 4 6.3 24.2 2.1 2 0 0 2 2 2 0 Coronavirus nucleocapsid protein CAF-1_p150 PF11600.3 CDI86902.1 - 0.89 8.8 50.7 0.04 13.2 25.8 2.1 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF2201_N PF13203.1 CDI86902.1 - 1.3 8.1 37.5 0.038 13.1 18.8 2.2 2 0 0 2 2 2 0 Putative metallopeptidase domain AUX_IAA PF02309.11 CDI86902.1 - 2.6 7.7 28.0 7.6 6.2 17.1 2.2 2 0 0 2 2 2 0 AUX/IAA family AvrE PF11725.3 CDI86902.1 - 4 4.3 35.2 4.8 4.0 24.4 1.1 1 0 0 1 1 1 0 Pathogenicity factor DUF966 PF06136.8 CDI86902.1 - 5.3 6.3 32.4 21 4.4 19.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF966) FLO_LFY PF01698.11 CDI86902.1 - 8.7 5.0 32.4 15 4.2 19.5 2.0 2 0 0 2 2 2 0 Floricaula / Leafy protein MIP-T3 PF10243.4 CDI86903.1 - 0.0016 17.0 32.2 0.0016 17.0 22.3 3.1 3 0 0 3 3 3 2 Microtubule-binding protein MIP-T3 NifU PF01106.12 CDI86905.1 - 2.1e-09 36.9 0.0 1.1e-07 31.5 0.0 2.5 2 1 0 2 2 2 1 NifU-like domain NESP55 PF06390.7 CDI86905.1 - 3.2 7.0 13.8 0.3 10.4 6.1 1.7 2 0 0 2 2 2 0 Neuroendocrine-specific golgi protein P55 (NESP55) DED PF01335.16 CDI86907.1 - 0.069 13.2 0.0 0.4 10.8 0.0 1.9 2 0 0 2 2 2 0 Death effector domain SDA1 PF05285.7 CDI86908.1 - 5e-05 22.7 24.9 0.0053 16.0 11.2 2.2 2 0 0 2 2 2 2 SDA1 S4 PF01479.20 CDI86908.1 - 0.0023 17.3 0.0 0.0053 16.1 0.0 1.5 1 0 0 1 1 1 1 S4 domain AAA_23 PF13476.1 CDI86908.1 - 0.0061 16.8 11.8 0.0061 16.8 8.2 2.3 2 0 0 2 2 2 1 AAA domain Herpes_MCP PF03122.9 CDI86908.1 - 2.7 5.2 12.0 0.13 9.5 3.6 1.8 2 0 0 2 2 2 0 Herpes virus major capsid protein LMBR1 PF04791.11 CDI86909.1 - 0.0048 15.5 0.0 0.0048 15.5 0.0 5.5 2 2 2 4 4 4 1 LMBR1-like membrane protein Activator_LAG-3 PF11498.3 CDI86911.1 - 0.028 13.1 26.3 0.055 12.2 18.2 1.5 1 0 0 1 1 1 0 Transcriptional activator LAG-3 TraG-D_C PF12696.2 CDI86911.1 - 0.09 12.6 0.1 0.09 12.6 0.1 3.1 3 0 0 3 3 3 0 TraM recognition site of TraD and TraG CbiD PF01888.12 CDI86911.1 - 2.1 7.2 6.4 3.6 6.4 4.4 1.3 1 0 0 1 1 1 0 CbiD LCD1 PF09798.4 CDI86911.1 - 5.7 4.7 10.7 8.7 4.2 7.4 1.2 1 0 0 1 1 1 0 DNA damage checkpoint protein Activator_LAG-3 PF11498.3 CDI86913.1 - 0.00035 19.4 5.1 0.00035 19.4 3.5 5.8 4 1 1 5 5 5 3 Transcriptional activator LAG-3 MCPVI PF02993.9 CDI86914.1 - 0.045 13.9 8.2 0.044 13.9 5.7 1.0 1 0 0 1 1 1 0 Minor capsid protein VI DDRGK PF09756.4 CDI86914.1 - 0.15 11.4 12.3 0.15 11.4 8.5 1.1 1 0 0 1 1 1 0 DDRGK domain Draxin PF15550.1 CDI86914.1 - 0.2 11.2 9.4 0.21 11.2 6.5 1.0 1 0 0 1 1 1 0 Draxin Cwf_Cwc_15 PF04889.7 CDI86914.1 - 0.22 11.1 16.9 0.25 11.0 11.7 1.0 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Herpes_env PF01673.13 CDI86914.1 - 0.32 9.5 7.6 0.33 9.4 5.3 1.0 1 0 0 1 1 1 0 Herpesvirus putative major envelope glycoprotein TFIIF_alpha PF05793.7 CDI86914.1 - 1.1 7.5 13.2 1.3 7.3 9.1 1.0 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) PAT1 PF09770.4 CDI86914.1 - 1.3 7.1 32.3 1.3 7.1 22.4 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Prog_receptor PF02161.10 CDI86914.1 - 1.5 7.6 15.6 1.6 7.4 10.8 1.1 1 0 0 1 1 1 0 Progesterone receptor RAP1 PF07218.6 CDI86914.1 - 1.6 6.7 9.4 1.6 6.6 6.5 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Plasmodium_Vir PF05795.6 CDI86914.1 - 1.7 7.7 11.1 1.9 7.6 7.7 1.0 1 0 0 1 1 1 0 Plasmodium vivax Vir protein DUF4407 PF14362.1 CDI86914.1 - 2.1 7.2 10.7 2 7.2 7.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Tim54 PF11711.3 CDI86914.1 - 2.1 6.8 8.8 2.1 6.8 6.1 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 TMEM51 PF15345.1 CDI86914.1 - 2.5 7.7 16.8 2.8 7.5 11.7 1.1 1 0 0 1 1 1 0 Transmembrane protein 51 Med15 PF09606.5 CDI86914.1 - 2.7 6.0 37.9 2.8 6.0 26.3 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal G-7-MTase PF12803.2 CDI86914.1 - 3.1 6.8 10.2 3.3 6.7 7.1 1.0 1 0 0 1 1 1 0 mRNA (guanine-7-)methyltransferase (G-7-MTase) Apc15p PF05841.6 CDI86914.1 - 3.3 8.4 22.0 4.7 7.9 15.3 1.3 1 0 0 1 1 1 0 Apc15p protein DUF2052 PF09747.4 CDI86914.1 - 3.9 7.3 17.3 4.3 7.2 12.0 1.1 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) Hid1 PF12722.2 CDI86914.1 - 4 5.0 22.4 4.3 4.9 15.5 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Bud13 PF09736.4 CDI86914.1 - 4.1 7.6 15.2 4.6 7.5 10.5 1.2 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex DUF3513 PF12026.3 CDI86914.1 - 4.2 6.8 19.9 4.7 6.6 13.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3513) FimP PF09766.4 CDI86914.1 - 5 6.0 22.5 5.2 6.0 15.6 1.2 1 0 0 1 1 1 0 Fms-interacting protein Peptidase_S49_N PF08496.5 CDI86914.1 - 5 6.8 9.4 5.3 6.8 6.5 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal vMSA PF00695.14 CDI86914.1 - 6.1 5.9 7.6 6.7 5.8 5.2 1.0 1 0 0 1 1 1 0 Major surface antigen from hepadnavirus FAM60A PF15396.1 CDI86914.1 - 6.2 6.5 18.9 7.2 6.2 13.1 1.1 1 0 0 1 1 1 0 Protein Family FAM60A DUF605 PF04652.11 CDI86914.1 - 6.7 6.0 25.9 10 5.4 17.9 1.3 1 0 0 1 1 1 0 Vta1 like Utp14 PF04615.8 CDI86914.1 - 7.7 4.5 20.2 8.6 4.3 14.0 1.0 1 0 0 1 1 1 0 Utp14 protein GP40 PF11025.3 CDI86914.1 - 8.3 5.9 10.2 7.8 6.0 6.6 1.3 1 1 0 1 1 1 0 Glycoprotein GP40 of Cryptosporidium DUF4175 PF13779.1 CDI86914.1 - 8.6 3.9 36.1 8.9 3.8 25.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Spc7_N PF15402.1 CDI86914.1 - 9 4.1 27.5 9.9 4.0 19.1 1.0 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 Tudor-knot PF11717.3 CDI86915.1 - 7e-10 38.4 0.1 1.8e-07 30.7 0.0 2.2 2 0 0 2 2 2 2 RNA binding activity-knot of a chromodomain LRR_4 PF12799.2 CDI86916.1 - 2.2e-08 33.5 0.1 5.3e-08 32.2 0.1 1.6 1 0 0 1 1 1 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CDI86916.1 - 1.1e-06 28.2 0.3 2.8e-06 26.9 0.2 1.7 1 1 0 1 1 1 1 Leucine rich repeat LRR_1 PF00560.28 CDI86916.1 - 1.8e-06 27.1 0.2 0.00021 20.8 1.0 2.6 2 0 0 2 2 2 1 Leucine Rich Repeat LRR_6 PF13516.1 CDI86916.1 - 0.0019 18.0 0.5 0.039 14.0 0.3 2.9 2 1 0 2 2 2 1 Leucine Rich repeat LRR_7 PF13504.1 CDI86916.1 - 0.0036 17.2 1.6 0.012 15.6 0.2 2.6 3 1 0 3 3 3 1 Leucine rich repeat polyprenyl_synt PF00348.12 CDI86916.1 - 0.089 11.6 0.0 0.12 11.1 0.0 1.2 1 0 0 1 1 1 0 Polyprenyl synthetase RAP1 PF07218.6 CDI86917.1 - 0.15 10.0 2.2 0.23 9.5 1.5 1.3 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Serinc PF03348.10 CDI86917.1 - 1.2 7.7 5.8 0.3 9.7 0.6 2.1 2 0 0 2 2 2 0 Serine incorporator (Serinc) CAF-1_p150 PF11600.3 CDI86918.1 - 0.025 13.9 4.9 0.035 13.4 3.4 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Med15 PF09606.5 CDI86918.1 - 2.9 5.9 17.3 3.6 5.6 12.0 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF724 PF05266.9 CDI86918.1 - 4.5 6.8 7.8 9.2 5.8 5.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Radial_spoke_3 PF06098.6 CDI86918.1 - 9.4 5.1 15.7 15 4.4 10.9 1.2 1 0 0 1 1 1 0 Radial spoke protein 3 BAF1_ABF1 PF04684.8 CDI86919.1 - 0.00066 18.6 9.2 0.00066 18.6 6.4 6.6 5 2 0 6 6 6 1 BAF1 / ABF1 chromatin reorganising factor DUF3474 PF11960.3 CDI86921.1 - 0.43 10.5 1.9 0.46 10.5 1.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3474) FKS1_dom1 PF14288.1 CDI86921.1 - 0.74 9.7 5.1 0.83 9.5 3.5 1.1 1 0 0 1 1 1 0 1,3-beta-glucan synthase subunit FKS1, domain-1 FimP PF09766.4 CDI86922.1 - 6.8e-05 22.0 2.0 0.0001 21.5 1.4 1.4 1 0 0 1 1 1 1 Fms-interacting protein AmoA PF05145.7 CDI86922.1 - 0.0031 16.6 1.5 0.0049 15.9 1.1 1.4 1 0 0 1 1 1 1 Putative ammonia monooxygenase Spt20 PF12090.3 CDI86922.1 - 0.0042 16.4 1.6 0.0042 16.4 1.1 1.6 2 1 0 2 2 2 1 Spt20 family DUF3357 PF11837.3 CDI86922.1 - 0.55 10.0 3.3 0.28 11.0 0.5 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3357) Claudin_2 PF13903.1 CDI86922.1 - 0.64 9.6 10.7 0.21 11.2 1.5 2.2 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction Baculo_PP31 PF05311.6 CDI86922.1 - 1.2 8.3 8.0 2.3 7.4 5.5 1.4 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) CIAPIN1 PF05093.8 CDI86922.1 - 3.2 7.8 7.6 0.23 11.5 0.7 2.3 2 1 0 2 2 2 0 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis FAM60A PF15396.1 CDI86922.1 - 3.4 7.3 8.1 0.47 10.1 2.1 1.9 2 0 0 2 2 2 0 Protein Family FAM60A DUF3807 PF12720.2 CDI86922.1 - 4.8 7.3 16.3 0.73 9.9 5.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3807) F-protein PF00469.15 CDI86922.1 - 6.5 6.0 9.3 0.74 9.1 2.9 1.8 2 0 0 2 2 2 0 Negative factor, (F-Protein) or Nef Ribosomal_60s PF00428.14 CDI86923.1 - 0.00015 22.0 10.7 0.00025 21.3 7.4 1.4 1 0 0 1 1 1 1 60s Acidic ribosomal protein RskA PF10099.4 CDI86923.1 - 0.00021 21.0 2.5 0.00026 20.7 1.8 1.1 1 0 0 1 1 1 1 Anti-sigma-K factor rskA U79_P34 PF03064.11 CDI86923.1 - 0.00052 19.6 10.0 0.00068 19.2 7.0 1.2 1 0 0 1 1 1 1 HSV U79 / HCMV P34 DUF2217 PF10265.4 CDI86923.1 - 0.0074 15.0 21.7 0.0086 14.8 15.0 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2217) Paf1 PF03985.8 CDI86923.1 - 0.012 14.3 15.7 0.015 14.0 10.9 1.1 1 0 0 1 1 1 0 Paf1 DUF1510 PF07423.6 CDI86923.1 - 0.055 12.8 18.8 0.071 12.4 13.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Ycf1 PF05758.7 CDI86923.1 - 0.075 10.7 10.7 0.075 10.7 7.4 1.0 1 0 0 1 1 1 0 Ycf1 DUF3801 PF12687.2 CDI86923.1 - 0.12 11.9 13.0 0.14 11.6 9.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3801) Cwf_Cwc_15 PF04889.7 CDI86923.1 - 0.18 11.5 19.5 0.21 11.2 13.5 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein CobT PF06213.7 CDI86923.1 - 0.19 10.8 13.2 0.24 10.4 9.2 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF4259 PF14078.1 CDI86923.1 - 0.2 12.1 3.3 0.26 11.7 2.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4259) ADP_ribosyl_GH PF03747.9 CDI86923.1 - 0.3 10.8 4.2 0.35 10.5 2.9 1.1 1 0 0 1 1 1 0 ADP-ribosylglycohydrolase Pex16 PF08610.5 CDI86923.1 - 0.32 9.9 11.4 0.34 9.8 7.9 1.2 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) GPCR_chapero_1 PF11904.3 CDI86923.1 - 0.33 10.0 13.2 0.41 9.7 9.2 1.1 1 0 0 1 1 1 0 GPCR-chaperone Menin PF05053.8 CDI86923.1 - 0.37 8.9 13.4 0.38 8.8 9.3 1.0 1 0 0 1 1 1 0 Menin DUF3381 PF11861.3 CDI86923.1 - 0.38 10.2 11.6 0.53 9.7 8.0 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF3381) AbiH PF14253.1 CDI86923.1 - 0.45 10.0 7.5 0.55 9.7 5.2 1.3 1 0 0 1 1 1 0 Bacteriophage abortive infection AbiH DNA_pol_viral_N PF00242.12 CDI86923.1 - 0.48 9.3 26.0 0.56 9.1 18.0 1.0 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain Med13_N PF11597.3 CDI86923.1 - 0.55 8.8 18.6 0.7 8.5 12.9 1.1 1 0 0 1 1 1 0 Mediator complex subunit 13 N-terminal DUF4175 PF13779.1 CDI86923.1 - 0.68 7.5 18.4 0.77 7.3 12.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) FAM70 PF14967.1 CDI86923.1 - 0.73 8.9 6.5 0.91 8.6 4.5 1.1 1 0 0 1 1 1 0 FAM70 protein FHIPEP PF00771.15 CDI86923.1 - 0.89 7.7 6.4 0.99 7.6 4.5 1.1 1 0 0 1 1 1 0 FHIPEP family DUF4604 PF15377.1 CDI86923.1 - 0.93 9.6 22.6 1.3 9.1 15.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) DUF2215 PF10225.4 CDI86923.1 - 0.94 8.8 13.5 1.2 8.5 9.3 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) Nucleo_P87 PF07267.6 CDI86923.1 - 0.95 8.0 12.4 1.1 7.9 8.6 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 DDRGK PF09756.4 CDI86923.1 - 1 8.7 13.2 1.2 8.4 9.2 1.1 1 0 0 1 1 1 0 DDRGK domain Neur_chan_memb PF02932.11 CDI86923.1 - 1.1 9.1 13.3 1.2 8.9 9.2 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Peptidase_S30 PF01577.11 CDI86923.1 - 1.1 8.6 11.0 1.2 8.4 7.6 1.1 1 0 0 1 1 1 0 Potyvirus P1 protease Macoilin PF09726.4 CDI86923.1 - 1.1 7.4 30.1 1.3 7.1 20.9 1.0 1 0 0 1 1 1 0 Transmembrane protein Lin-8 PF03353.10 CDI86923.1 - 1.2 8.4 17.7 1.3 8.2 12.3 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist FAM60A PF15396.1 CDI86923.1 - 1.2 8.8 21.4 1.4 8.6 14.8 1.1 1 0 0 1 1 1 0 Protein Family FAM60A PepSY_2 PF13670.1 CDI86923.1 - 1.2 9.0 11.8 2 8.3 8.2 1.3 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain DUF2782 PF11191.3 CDI86923.1 - 1.6 8.7 5.9 2.4 8.1 4.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2782) Plasmodium_Vir PF05795.6 CDI86923.1 - 1.6 7.8 14.8 2.1 7.4 10.3 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Selenoprotein_S PF06936.6 CDI86923.1 - 1.7 8.1 13.7 2.4 7.6 9.5 1.3 1 0 0 1 1 1 0 Selenoprotein S (SelS) BORG_CEP PF14957.1 CDI86923.1 - 2 9.3 18.8 2.9 8.8 13.0 1.3 1 0 0 1 1 1 0 Cdc42 effector Mcm10 PF09332.6 CDI86923.1 - 2.4 7.3 21.9 3 7.1 15.2 1.1 1 0 0 1 1 1 0 Mcm10 replication factor Utp14 PF04615.8 CDI86923.1 - 2.7 6.0 24.6 3 5.8 17.0 1.0 1 0 0 1 1 1 0 Utp14 protein DUF3807 PF12720.2 CDI86923.1 - 2.7 8.1 20.9 3.6 7.7 14.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) CMV_1a PF12467.3 CDI86923.1 - 3.5 7.9 18.1 4.5 7.6 12.6 1.1 1 0 0 1 1 1 0 Cucumber mosaic virus 1a protein family Tetraspannin PF00335.15 CDI86923.1 - 3.6 6.7 5.4 4.4 6.5 3.8 1.1 1 0 0 1 1 1 0 Tetraspanin family Hid1 PF12722.2 CDI86923.1 - 3.7 5.1 22.8 4 4.9 15.8 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF2052 PF09747.4 CDI86923.1 - 3.9 7.3 16.7 5.1 6.9 11.6 1.2 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) Spc7_N PF15402.1 CDI86923.1 - 4.4 5.1 27.4 5.2 4.9 19.0 1.0 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 CDC45 PF02724.9 CDI86923.1 - 4.5 5.1 18.8 5.1 4.9 13.0 1.1 1 0 0 1 1 1 0 CDC45-like protein Dicty_REP PF05086.7 CDI86923.1 - 4.9 4.7 17.6 5.3 4.6 12.2 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein VIT1 PF01988.14 CDI86923.1 - 5.8 6.3 7.6 6.5 6.1 5.3 1.2 1 0 0 1 1 1 0 VIT family RAP1 PF07218.6 CDI86923.1 - 6.7 4.6 21.7 7.6 4.4 15.0 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) SAPS PF04499.10 CDI86923.1 - 6.8 5.2 16.4 7.3 5.0 11.4 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Peptidase_S64 PF08192.6 CDI86923.1 - 8.4 4.5 21.0 9.9 4.3 14.6 1.1 1 0 0 1 1 1 0 Peptidase family S64 Mem_trans PF03547.13 CDI86923.1 - 8.6 4.5 15.3 9.3 4.4 10.6 1.1 1 0 0 1 1 1 0 Membrane transport protein DUF572 PF04502.8 CDI86923.1 - 8.8 5.4 25.7 10 5.2 17.8 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Transformer PF06495.6 CDI86923.1 - 9.1 6.1 18.7 11 5.7 13.0 1.2 1 0 0 1 1 1 0 Fruit fly transformer protein zf-CCCH PF00642.19 CDI86927.1 - 0.0014 18.2 1.0 0.0027 17.3 0.7 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) PAT1 PF09770.4 CDI86928.1 - 5.5 5.1 15.9 7.5 4.6 11.0 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 FXa_inhibition PF14670.1 CDI86929.1 - 0.0023 18.0 69.5 0.018 15.1 2.6 6.2 5 1 0 5 5 5 4 Coagulation Factor Xa inhibitory site cEGF PF12662.2 CDI86929.1 - 0.0085 15.7 0.7 0.0085 15.7 0.5 6.5 6 0 0 6 6 6 4 Complement Clr-like EGF-like EGF_3 PF12947.2 CDI86929.1 - 1.7 8.6 52.4 0.1 12.5 7.7 6.2 5 1 1 6 6 6 0 EGF domain EGF_MSP1_1 PF12946.2 CDI86929.1 - 5.6 6.8 28.5 3.9 7.3 0.2 5.3 5 0 0 5 5 5 0 MSP1 EGF domain 1 NTP_transf_2 PF01909.18 CDI86930.1 - 0.14 12.5 0.1 0.28 11.5 0.0 1.4 1 0 0 1 1 1 0 Nucleotidyltransferase domain Nucleoside_tran PF01733.13 CDI86931.1 - 2.4e-15 56.4 10.4 4.1e-15 55.7 7.2 1.3 1 0 0 1 1 1 1 Nucleoside transporter RRM_6 PF14259.1 CDI86933.1 - 3.7e-09 36.4 0.0 5.1e-09 35.9 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CDI86933.1 - 3e-08 33.1 0.0 4.4e-08 32.6 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CDI86933.1 - 1.2e-05 25.0 0.0 1.8e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) LSM PF01423.17 CDI86934.1 - 7.3e-15 54.2 0.5 1.3e-14 53.4 0.3 1.4 1 0 0 1 1 1 1 LSM domain DUF2335 PF10097.4 CDI86934.1 - 3.8 7.2 7.5 6.3 6.5 0.0 3.6 3 1 1 4 4 4 0 Predicted membrane protein (DUF2335) IMCp PF12314.3 CDI86935.1 - 2.1e-33 114.3 92.6 1.7e-16 60.1 18.8 4.9 1 1 4 5 5 5 4 Inner membrane complex protein IMCp PF12314.3 CDI86936.1 - 9.8e-30 102.5 60.1 9.2e-29 99.4 28.3 5.4 2 2 3 5 5 5 2 Inner membrane complex protein NAD_binding_4 PF07993.7 CDI86937.1 - 1.5e-54 184.5 0.0 2.5e-54 183.8 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein Sulfotransfer_1 PF00685.22 CDI86937.1 - 5.1e-17 62.0 0.1 1.2e-16 60.7 0.0 1.6 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.1 CDI86937.1 - 1.9e-14 54.9 0.1 5.2e-14 53.4 0.1 1.8 1 0 0 1 1 1 1 Sulfotransferase family PP-binding PF00550.20 CDI86937.1 - 2.2e-11 43.8 0.0 7.7e-11 42.1 0.0 2.0 1 0 0 1 1 1 1 Phosphopantetheine attachment site Epimerase PF01370.16 CDI86937.1 - 2.5e-09 36.9 0.0 4.9e-09 35.9 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1331 PF07048.6 CDI86937.1 - 0.093 12.1 0.2 0.66 9.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1331) stn_TNFRSF12A PF12191.3 CDI86938.1 - 0.0042 17.1 0.1 0.0047 16.9 0.1 1.1 1 0 0 1 1 1 1 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain TRP PF06011.7 CDI86938.1 - 0.0069 15.0 0.5 0.0076 14.8 0.3 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel Myco_19_kDa PF05481.7 CDI86938.1 - 0.0098 15.7 0.0 0.012 15.4 0.0 1.1 1 0 0 1 1 1 1 Mycobacterium 19 kDa lipoprotein antigen DUF3675 PF12428.3 CDI86938.1 - 0.022 15.0 0.0 0.022 15.0 0.0 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3675) Peptidase_M56 PF05569.6 CDI86938.1 - 0.023 13.6 0.7 0.028 13.3 0.5 1.1 1 0 0 1 1 1 0 BlaR1 peptidase M56 PepSY_TM_2 PF13703.1 CDI86938.1 - 0.025 14.7 0.8 0.043 13.9 0.1 1.7 2 0 0 2 2 2 0 PepSY-associated TM helix Pheromone PF08015.6 CDI86938.1 - 0.03 15.1 1.3 0.046 14.5 0.9 1.2 1 0 0 1 1 1 0 Fungal mating-type pheromone PH_5 PF15405.1 CDI86938.1 - 0.083 12.8 0.1 0.093 12.6 0.1 1.1 1 0 0 1 1 1 0 Pleckstrin homology domain Hum_adeno_E3A PF05393.6 CDI86938.1 - 0.092 12.4 0.1 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Human adenovirus early E3A glycoprotein DUF515 PF04415.7 CDI86938.1 - 0.1 10.8 2.6 0.11 10.7 1.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF515) DUF3844 PF12955.2 CDI86938.1 - 0.15 12.1 0.4 0.23 11.5 0.3 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF3844) Sex_peptide PF08138.6 CDI86938.1 - 0.16 11.8 1.8 1.7 8.5 0.0 2.2 2 0 0 2 2 2 0 Sex peptide (SP) family Fig1 PF12351.3 CDI86938.1 - 0.3 10.9 5.2 2.2 8.1 0.5 2.2 2 0 0 2 2 2 0 Ca2+ regulator and membrane fusion protein Fig1 NADH5_C PF06455.6 CDI86938.1 - 0.62 9.4 7.0 1.6 8.0 1.3 2.0 2 0 0 2 2 2 0 NADH dehydrogenase subunit 5 C-terminus ATP-synt_8 PF00895.15 CDI86938.1 - 0.92 9.7 11.5 2.2 8.5 1.6 2.2 2 0 0 2 2 2 0 ATP synthase protein 8 Oxidored_q3 PF00499.15 CDI86938.1 - 1.4 8.7 8.9 2.5 7.8 6.2 1.3 1 1 0 1 1 1 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 SR-25 PF10500.4 CDI86938.1 - 4.5 6.6 14.9 6.5 6.1 10.3 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Rad60-SLD_2 PF13881.1 CDI86939.1 - 4.2e-07 29.8 0.1 4.2e-07 29.8 0.1 5.0 5 2 1 6 6 6 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD PF11976.3 CDI86939.1 - 0.00088 18.9 0.0 0.00088 18.9 0.0 3.1 4 0 0 4 4 4 1 Ubiquitin-2 like Rad60 SUMO-like zf-HIT PF04438.11 CDI86940.1 - 1.2e-07 31.2 12.5 2.2e-07 30.3 8.7 1.4 1 0 0 1 1 1 1 HIT zinc finger Parvo_coat PF00740.13 CDI86940.1 - 7.3 5.4 50.1 3 6.7 9.7 2.1 2 0 0 2 2 2 0 Parvovirus coat protein VP2 polyprenyl_synt PF00348.12 CDI86941.1 - 0.27 10.0 10.7 0.31 9.8 7.4 1.0 1 0 0 1 1 1 0 Polyprenyl synthetase Ribosomal_60s PF00428.14 CDI86941.1 - 0.3 11.5 11.0 0.45 10.9 7.7 1.3 1 0 0 1 1 1 0 60s Acidic ribosomal protein PsbW PF07123.7 CDI86941.1 - 1.4 9.0 6.1 1.4 8.9 4.2 1.2 1 0 0 1 1 1 0 Photosystem II reaction centre W protein (PsbW) Pox_F12L PF03337.8 CDI86941.1 - 5 4.9 7.6 5.6 4.7 5.3 1.0 1 0 0 1 1 1 0 Poxvirus F12L protein FAM176 PF14851.1 CDI86942.1 - 1 9.0 12.0 1.1 8.9 8.3 1.1 1 0 0 1 1 1 0 FAM176 family DUF1510 PF07423.6 CDI86942.1 - 1.1 8.6 20.7 1.1 8.5 14.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Pex14_N PF04695.8 CDI86942.1 - 1.1 9.3 16.8 1.2 9.2 11.7 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region NinG PF05766.7 CDI86942.1 - 1.9 8.2 17.0 2.1 8.0 11.8 1.0 1 0 0 1 1 1 0 Bacteriophage Lambda NinG protein Peptidase_S49_N PF08496.5 CDI86942.1 - 2.4 7.9 15.5 2.9 7.6 10.8 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal PAT1 PF09770.4 CDI86942.1 - 2.6 6.1 31.1 2.5 6.2 21.5 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF3306 PF11748.3 CDI86942.1 - 3.7 8.2 14.1 4.8 7.8 9.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3306) Tim54 PF11711.3 CDI86942.1 - 3.8 6.0 14.9 3.5 6.1 10.3 1.0 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 HABP4_PAI-RBP1 PF04774.10 CDI86942.1 - 3.9 8.0 20.2 5.3 7.5 14.0 1.2 1 0 0 1 1 1 0 Hyaluronan / mRNA binding family Radial_spoke_3 PF06098.6 CDI86942.1 - 5.3 5.9 26.6 5.6 5.8 18.5 1.0 1 0 0 1 1 1 0 Radial spoke protein 3 zf-CpG_bind_C PF12269.3 CDI86942.1 - 6 6.2 17.0 6.7 6.1 11.8 1.0 1 0 0 1 1 1 0 CpG binding protein zinc finger C terminal domain Dala_Dala_lig_N PF01820.16 CDI86942.1 - 7.2 6.9 8.9 9.5 6.5 6.1 1.3 1 0 0 1 1 1 0 D-ala D-ala ligase N-terminus Eapp_C PF10238.4 CDI86942.1 - 7.6 6.4 15.4 11 5.8 10.7 1.3 1 0 0 1 1 1 0 E2F-associated phosphoprotein Rtf2 PF04641.7 CDI86942.1 - 8.3 5.5 18.6 8.9 5.4 12.9 1.0 1 0 0 1 1 1 0 Rtf2 RING-finger Glyco_transf_15 PF01793.11 CDI86942.1 - 9.6 5.0 15.6 9.7 5.0 10.8 1.1 1 0 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase Fe_hyd_lg_C PF02906.9 CDI86943.1 - 1.3e-10 41.0 3.5 2e-05 24.0 0.0 3.7 4 1 0 4 4 4 2 Iron only hydrogenase large subunit, C-terminal domain LMBR1 PF04791.11 CDI86943.1 - 9.1e-05 21.2 23.9 0.00018 20.2 15.1 2.1 2 0 0 2 2 2 1 LMBR1-like membrane protein MIP-T3 PF10243.4 CDI86943.1 - 0.0011 17.6 35.2 0.0011 17.6 24.4 4.1 3 1 1 4 4 4 1 Microtubule-binding protein MIP-T3 VIT1 PF01988.14 CDI86943.1 - 0.0013 18.2 6.6 0.0013 18.2 4.6 4.9 4 1 1 5 5 5 2 VIT family Suf PF05843.9 CDI86943.1 - 0.0095 15.6 2.0 0.0095 15.6 1.4 4.5 2 1 0 3 3 3 1 Suppressor of forked protein (Suf) Herpes_UL45 PF05473.7 CDI86943.1 - 0.02 14.3 1.6 0.038 13.4 0.0 2.3 2 1 0 2 2 2 0 UL45 protein PAT1 PF09770.4 CDI86943.1 - 0.023 12.9 133.4 0.17 10.0 78.2 2.5 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 Tweety PF04906.8 CDI86943.1 - 0.73 8.1 23.9 0.042 12.2 10.8 2.7 1 1 1 2 2 2 0 Tweety DUF1700 PF08006.6 CDI86943.1 - 5.9 6.1 8.7 13 5.0 6.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1700) CDC27 PF09507.5 CDI86944.1 - 0.059 12.5 11.6 0.061 12.5 8.0 1.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Viral_P18 PF04521.8 CDI86944.1 - 0.065 12.6 4.2 0.079 12.3 2.9 1.3 1 0 0 1 1 1 0 ssRNA positive strand viral 18kD cysteine rich protein FYDLN_acid PF09538.5 CDI86944.1 - 0.08 13.5 8.4 0.093 13.3 5.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) SelP_N PF04592.9 CDI86944.1 - 0.097 12.0 7.2 0.11 11.9 5.0 1.0 1 0 0 1 1 1 0 Selenoprotein P, N terminal region FimP PF09766.4 CDI86944.1 - 0.1 11.6 20.3 0.11 11.4 14.1 1.1 1 0 0 1 1 1 0 Fms-interacting protein CKAP2_C PF15297.1 CDI86944.1 - 0.2 10.4 13.0 0.23 10.2 9.0 1.0 1 0 0 1 1 1 0 Cytoskeleton-associated protein 2 C-terminus FLO_LFY PF01698.11 CDI86944.1 - 0.27 10.0 12.4 0.28 9.9 8.6 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein PAT1 PF09770.4 CDI86944.1 - 0.41 8.8 21.5 0.43 8.7 14.9 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 PsbW PF07123.7 CDI86944.1 - 0.45 10.5 6.8 0.63 10.1 4.7 1.2 1 0 0 1 1 1 0 Photosystem II reaction centre W protein (PsbW) DUF1510 PF07423.6 CDI86944.1 - 0.5 9.6 16.5 0.55 9.5 11.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DUF3381 PF11861.3 CDI86944.1 - 0.53 9.7 10.9 0.58 9.6 7.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) DUF4557 PF15101.1 CDI86944.1 - 0.55 10.0 18.4 0.62 9.8 12.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) Hid1 PF12722.2 CDI86944.1 - 0.65 7.6 12.6 0.71 7.4 8.7 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein VIT1 PF01988.14 CDI86944.1 - 0.76 9.2 6.8 0.84 9.0 4.7 1.1 1 0 0 1 1 1 0 VIT family DnaJ-X PF14308.1 CDI86944.1 - 0.83 8.8 10.3 0.93 8.7 7.1 1.1 1 0 0 1 1 1 0 X-domain of DnaJ-containing Band_3_cyto PF07565.8 CDI86944.1 - 0.84 9.0 9.4 0.91 8.9 6.5 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain PPP4R2 PF09184.6 CDI86944.1 - 0.87 9.0 11.9 0.95 8.9 8.3 1.0 1 0 0 1 1 1 0 PPP4R2 Gag_spuma PF03276.9 CDI86944.1 - 0.87 7.8 20.8 0.93 7.7 14.4 1.1 1 0 0 1 1 1 0 Spumavirus gag protein DUF3449 PF11931.3 CDI86944.1 - 0.89 9.0 10.4 0.98 8.8 7.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3449) SRP-alpha_N PF04086.8 CDI86944.1 - 0.91 8.8 16.2 1 8.7 11.2 1.0 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Plasmodium_Vir PF05795.6 CDI86944.1 - 0.95 8.5 5.8 0.98 8.5 4.0 1.0 1 0 0 1 1 1 0 Plasmodium vivax Vir protein FNIP_N PF14636.1 CDI86944.1 - 0.97 9.9 9.7 1.1 9.6 6.7 1.2 1 0 0 1 1 1 0 Folliculin-interacting protein N-terminus TEX19 PF15553.1 CDI86944.1 - 0.98 9.2 8.1 1.1 9.0 5.6 1.2 1 0 0 1 1 1 0 Testis-expressed protein 19 CobT PF06213.7 CDI86944.1 - 1 8.4 16.6 1 8.4 11.5 1.0 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT CDK5_activator PF03261.10 CDI86944.1 - 1 8.6 11.3 1.1 8.4 7.8 1.0 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein DUF966 PF06136.8 CDI86944.1 - 1 8.7 10.9 1.1 8.5 7.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Tim54 PF11711.3 CDI86944.1 - 1.1 7.7 9.5 1.2 7.6 6.6 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Spore_coat_CotO PF14153.1 CDI86944.1 - 1.2 8.5 17.2 1.4 8.3 11.9 1.1 1 0 0 1 1 1 0 Spore coat protein CotO FAM60A PF15396.1 CDI86944.1 - 1.2 8.7 8.0 1.4 8.6 5.5 1.1 1 0 0 1 1 1 0 Protein Family FAM60A DUF1675 PF07897.6 CDI86944.1 - 1.3 8.8 13.1 1.3 8.7 9.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) TRAP_alpha PF03896.11 CDI86944.1 - 1.3 7.9 8.5 1.4 7.8 5.9 1.0 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit RR_TM4-6 PF06459.7 CDI86944.1 - 1.3 8.8 13.8 1.5 8.6 9.6 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Baculo_PP31 PF05311.6 CDI86944.1 - 1.4 8.1 10.5 1.4 8.1 7.3 1.1 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) NARP1 PF12569.3 CDI86944.1 - 1.4 7.5 13.9 1.6 7.4 9.6 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 XAP5 PF04921.9 CDI86944.1 - 1.5 8.3 7.9 1.5 8.3 5.5 1.1 1 0 0 1 1 1 0 XAP5, circadian clock regulator SGIII PF15467.1 CDI86944.1 - 1.6 7.7 14.2 1.8 7.5 9.8 1.0 1 0 0 1 1 1 0 Secretogranin-3 LIM_bind PF01803.11 CDI86944.1 - 1.6 7.7 11.8 1.7 7.6 8.1 1.1 1 0 0 1 1 1 0 LIM-domain binding protein DUF3408 PF11888.3 CDI86944.1 - 1.6 8.6 9.7 2 8.3 6.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) PP_M1 PF03012.9 CDI86944.1 - 1.7 7.9 11.4 1.9 7.7 7.9 1.0 1 0 0 1 1 1 0 Phosphoprotein Shisa PF13908.1 CDI86944.1 - 1.9 8.6 10.7 2.1 8.4 7.4 1.1 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator FAM176 PF14851.1 CDI86944.1 - 1.9 8.1 9.1 2.5 7.7 6.3 1.1 1 0 0 1 1 1 0 FAM176 family DHHW PF14286.1 CDI86944.1 - 2 7.6 11.8 2.1 7.5 8.2 1.0 1 0 0 1 1 1 0 DHHW protein HA2 PF04408.18 CDI86944.1 - 2 8.4 6.1 4.2 7.4 4.3 1.6 1 1 0 1 1 1 0 Helicase associated domain (HA2) YABBY PF04690.8 CDI86944.1 - 2.1 8.5 6.3 2.4 8.3 4.3 1.1 1 0 0 1 1 1 0 YABBY protein DUF4175 PF13779.1 CDI86944.1 - 2.2 5.9 32.1 2.1 5.9 22.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Peptidase_S49_N PF08496.5 CDI86944.1 - 2.2 8.0 7.6 2.4 7.9 5.3 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal CDC45 PF02724.9 CDI86944.1 - 2.3 6.1 11.5 2.4 6.0 8.0 1.0 1 0 0 1 1 1 0 CDC45-like protein Raftlin PF15250.1 CDI86944.1 - 2.3 6.6 11.6 2.5 6.5 8.0 1.0 1 0 0 1 1 1 0 Raftlin TFIIA PF03153.8 CDI86944.1 - 2.3 8.0 25.1 2.5 7.8 17.4 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DREPP PF05558.7 CDI86944.1 - 2.4 7.9 7.2 2.9 7.6 5.0 1.1 1 0 0 1 1 1 0 DREPP plasma membrane polypeptide AIF_C PF14721.1 CDI86944.1 - 2.4 8.4 12.0 3 8.0 8.3 1.3 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Ycf1 PF05758.7 CDI86944.1 - 2.5 5.7 11.2 2.6 5.6 7.8 1.0 1 0 0 1 1 1 0 Ycf1 CPSF100_C PF13299.1 CDI86944.1 - 2.6 8.2 11.7 2.9 8.0 8.1 1.1 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Dicty_REP PF05086.7 CDI86944.1 - 2.7 5.6 8.9 2.9 5.5 6.2 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Paf1 PF03985.8 CDI86944.1 - 2.8 6.5 16.8 3.1 6.4 11.6 1.0 1 0 0 1 1 1 0 Paf1 Menin PF05053.8 CDI86944.1 - 3 5.9 12.8 3.1 5.8 8.9 1.0 1 0 0 1 1 1 0 Menin DDHD PF02862.12 CDI86944.1 - 3 7.5 14.3 3.2 7.5 9.9 1.0 1 0 0 1 1 1 0 DDHD domain eIF-3_zeta PF05091.7 CDI86944.1 - 3 6.3 14.3 3.2 6.2 9.9 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Suf PF05843.9 CDI86944.1 - 3.3 7.3 13.9 3.5 7.2 9.6 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) AUX_IAA PF02309.11 CDI86944.1 - 3.4 7.3 10.8 3.9 7.1 7.5 1.1 1 0 0 1 1 1 0 AUX/IAA family Med15 PF09606.5 CDI86944.1 - 3.5 5.6 36.0 3.9 5.5 24.9 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Sec62 PF03839.11 CDI86944.1 - 3.8 6.8 6.0 4 6.7 4.1 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 Neur_chan_memb PF02932.11 CDI86944.1 - 3.9 7.2 6.4 4.2 7.1 4.5 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region BTV_NS2 PF04514.7 CDI86944.1 - 4.2 6.1 9.4 4.3 6.1 6.5 1.0 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Herpes_env PF01673.13 CDI86944.1 - 4.2 5.8 8.3 4.5 5.7 5.7 1.0 1 0 0 1 1 1 0 Herpesvirus putative major envelope glycoprotein Rtf2 PF04641.7 CDI86944.1 - 4.3 6.4 14.2 4.8 6.3 9.9 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger RIC3 PF15361.1 CDI86944.1 - 4.5 7.4 11.2 5.7 7.1 7.8 1.3 1 0 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 DDRGK PF09756.4 CDI86944.1 - 4.5 6.6 16.6 5.4 6.3 11.5 1.1 1 0 0 1 1 1 0 DDRGK domain Activator_LAG-3 PF11498.3 CDI86944.1 - 4.9 5.7 31.8 5.2 5.7 22.1 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Presenilin PF01080.12 CDI86944.1 - 5 5.8 10.1 5.5 5.7 7.0 1.0 1 0 0 1 1 1 0 Presenilin Lin-8 PF03353.10 CDI86944.1 - 5 6.3 14.2 5.6 6.1 9.8 1.0 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist OATP PF03137.15 CDI86944.1 - 5.1 5.0 7.8 5.3 4.9 5.4 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family MDMPI_N PF11716.3 CDI86944.1 - 5.2 7.4 11.9 6.5 7.1 8.3 1.1 1 0 0 1 1 1 0 Mycothiol maleylpyruvate isomerase N-terminal domain Ndc1_Nup PF09531.5 CDI86944.1 - 5.3 5.3 8.6 5.3 5.3 6.0 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Peptidase_U57 PF05582.7 CDI86944.1 - 5.5 5.8 9.6 6.2 5.6 6.7 1.0 1 0 0 1 1 1 0 YabG peptidase U57 FemAB PF02388.11 CDI86944.1 - 5.6 5.5 13.3 6.3 5.3 9.2 1.0 1 0 0 1 1 1 0 FemAB family Gti1_Pac2 PF09729.4 CDI86944.1 - 5.6 6.7 8.3 6.5 6.5 5.8 1.1 1 0 0 1 1 1 0 Gti1/Pac2 family EIIBC-GUT_N PF03612.9 CDI86944.1 - 5.8 6.4 9.6 7.3 6.1 6.6 1.3 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Aminotran_1_2 PF00155.16 CDI86944.1 - 5.9 5.7 7.8 4.1 6.2 4.8 1.3 1 1 0 1 1 1 0 Aminotransferase class I and II PIH1 PF08190.7 CDI86944.1 - 6.2 6.1 16.2 6.6 6.0 11.3 1.0 1 0 0 1 1 1 0 pre-RNA processing PIH1/Nop17 DUF3533 PF12051.3 CDI86944.1 - 6.3 5.4 8.3 7.1 5.2 5.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3533) Paramyxo_ncap PF00973.14 CDI86944.1 - 6.5 5.3 9.5 6.8 5.2 6.6 1.0 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Med13_N PF11597.3 CDI86944.1 - 6.8 5.2 10.9 7.1 5.1 7.6 1.1 1 0 0 1 1 1 0 Mediator complex subunit 13 N-terminal VID27 PF08553.5 CDI86944.1 - 6.9 4.7 11.4 7.3 4.6 7.9 1.0 1 0 0 1 1 1 0 VID27 cytoplasmic protein F-protein PF00469.15 CDI86944.1 - 6.9 5.9 10.7 7.1 5.9 7.4 1.1 1 0 0 1 1 1 0 Negative factor, (F-Protein) or Nef Herpes_DNAp_acc PF04929.7 CDI86944.1 - 7 5.5 8.8 7.2 5.4 6.1 1.0 1 0 0 1 1 1 0 Herpes DNA replication accessory factor DUF2201_N PF13203.1 CDI86944.1 - 8 5.5 18.5 9 5.3 12.8 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain TATR PF03430.8 CDI86944.1 - 8.1 4.9 9.7 8.4 4.9 6.7 1.0 1 0 0 1 1 1 0 Trans-activating transcriptional regulator Serinc PF03348.10 CDI86944.1 - 8.2 5.0 13.0 8.8 4.9 9.0 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) GOLD_2 PF13897.1 CDI86944.1 - 8.2 6.6 6.8 11 6.2 4.7 1.3 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking DUF3373 PF11853.3 CDI86944.1 - 8.2 4.8 12.1 8.3 4.8 8.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) Pex16 PF08610.5 CDI86944.1 - 8.5 5.2 9.9 9.2 5.1 6.8 1.1 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) Gastrin PF00918.12 CDI86944.1 - 9.8 7.0 16.4 12 6.7 11.4 1.1 1 0 0 1 1 1 0 Gastrin/cholecystokinin family G0-G1_switch_2 PF15103.1 CDI86944.1 - 9.9 6.4 8.9 13 6.0 6.2 1.4 1 0 0 1 1 1 0 G0/G1 switch protein 2 Med3 PF11593.3 CDI86945.1 - 0.00028 20.2 0.6 0.00028 20.2 0.4 36.4 12 6 16 30 30 30 3 Mediator complex subunit 3 fungal Fcf2 PF08698.6 CDI86946.1 - 1.4e-06 28.2 6.5 1.7e-05 24.7 4.5 2.5 1 1 0 1 1 1 1 Fcf2 pre-rRNA processing DUF3376 PF11856.3 CDI86946.1 - 1.7 7.9 21.4 3.3 6.9 14.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3376) CAF-1_p150 PF11600.3 CDI86947.1 - 0.0012 18.2 8.8 0.0017 17.7 6.1 1.2 1 0 0 1 1 1 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal Corona_nucleoca PF00937.13 CDI86947.1 - 0.13 11.1 11.1 0.16 10.8 7.7 1.2 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein Suf PF05843.9 CDI86947.1 - 0.2 11.3 5.4 0.22 11.2 3.8 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Apt1 PF10351.4 CDI86947.1 - 0.59 8.9 5.4 0.73 8.6 3.7 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF966 PF06136.8 CDI86947.1 - 3 7.1 9.9 3.7 6.8 6.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF966) DUF4131 PF13567.1 CDI86948.1 - 0.56 9.5 0.0 0.56 9.5 0.0 8.1 6 1 0 6 6 6 0 Domain of unknown function (DUF4131) 7tm_1 PF00001.16 CDI86949.1 - 0.011 14.9 0.6 0.011 14.9 0.4 3.9 2 1 0 2 2 2 0 7 transmembrane receptor (rhodopsin family) SR-25 PF10500.4 CDI86949.1 - 0.014 14.9 15.3 0.014 14.9 10.6 3.4 2 1 1 3 3 3 0 Nuclear RNA-splicing-associated protein zf-RING_2 PF13639.1 CDI86950.1 - 1.2e-10 41.0 1.9 1.8e-10 40.4 1.3 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 CDI86950.1 - 2.6e-07 30.6 2.0 2.6e-07 30.6 1.4 1.7 2 0 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 CDI86950.1 - 4.1e-07 29.9 1.0 5.9e-07 29.4 0.7 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CDI86950.1 - 4.3e-07 29.4 0.7 6.3e-07 28.9 0.5 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CDI86950.1 - 2.2e-05 24.0 0.5 4.6e-05 23.0 0.4 1.6 1 0 0 1 1 1 1 zinc-RING finger domain RINGv PF12906.2 CDI86950.1 - 0.00016 21.5 1.3 0.00046 20.1 0.9 1.7 1 0 0 1 1 1 1 RING-variant domain zf-Apc11 PF12861.2 CDI86950.1 - 0.00023 20.9 0.5 0.00023 20.9 0.4 1.8 2 0 0 2 2 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.20 CDI86950.1 - 0.00047 19.7 1.5 0.00096 18.7 1.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-P11 PF03854.9 CDI86950.1 - 0.0039 16.6 0.7 0.0054 16.1 0.5 1.2 1 0 0 1 1 1 1 P-11 zinc finger zf-RING_4 PF14570.1 CDI86950.1 - 0.015 14.8 0.4 0.025 14.1 0.3 1.3 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain DUF913 PF06025.7 CDI86950.1 - 0.015 14.0 2.2 0.016 13.9 1.6 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Spt20 PF12090.3 CDI86950.1 - 0.022 14.1 5.8 0.022 14.1 4.0 1.2 1 0 0 1 1 1 0 Spt20 family DUF4557 PF15101.1 CDI86950.1 - 0.044 13.6 11.8 0.048 13.4 8.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) Suf PF05843.9 CDI86950.1 - 0.056 13.1 11.7 0.053 13.2 8.1 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) FANCL_C PF11793.3 CDI86950.1 - 0.11 12.4 4.2 1.6 8.7 3.0 2.3 1 1 1 2 2 2 0 FANCL C-terminal domain DUF2072 PF09845.4 CDI86950.1 - 0.17 11.7 3.5 0.18 11.7 2.5 1.2 1 0 0 1 1 1 0 Zn-ribbon containing protein (DUF2072) FimP PF09766.4 CDI86950.1 - 0.26 10.2 17.5 0.29 10.1 12.1 1.0 1 0 0 1 1 1 0 Fms-interacting protein DUF853 PF05872.7 CDI86950.1 - 0.93 7.7 7.7 1 7.6 5.3 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) SprA-related PF12118.3 CDI86950.1 - 4.8 6.4 26.3 5 6.3 18.2 1.0 1 0 0 1 1 1 0 SprA-related family Pex14_N PF04695.8 CDI86950.1 - 5.9 6.9 15.5 6.6 6.7 10.8 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region IMS PF00817.15 CDI86952.1 - 2e-06 27.6 13.2 2.7e-05 23.9 0.2 3.4 2 1 0 3 3 3 2 impB/mucB/samB family IncA PF04156.9 CDI86952.1 - 0.0001 21.9 33.5 0.00016 21.3 5.1 5.7 5 1 0 5 5 5 2 IncA protein OmpH PF03938.9 CDI86952.1 - 0.0043 16.9 18.0 0.0043 16.9 12.5 7.9 5 1 1 6 6 6 2 Outer membrane protein (OmpH-like) IMS_HHH PF11798.3 CDI86952.1 - 0.46 10.6 0.0 1.2 9.3 0.0 1.7 1 0 0 1 1 1 0 IMS family HHH motif Ycf1 PF05758.7 CDI86952.1 - 1.6 6.3 42.0 0.017 12.8 6.1 3.2 3 0 0 3 3 3 0 Ycf1 ATP-synt_10 PF05176.9 CDI86953.1 - 0.0011 18.3 0.0 0.0018 17.5 0.0 1.3 1 0 0 1 1 1 1 ATP10 protein DUF2367 PF10164.4 CDI86954.1 - 4.4 7.2 10.6 2.8 7.8 0.9 2.9 1 1 3 4 4 4 0 Uncharacterized conserved protein (DUF2367) SR-25 PF10500.4 CDI86955.1 - 0.00068 19.1 26.2 0.00075 19.0 18.1 1.0 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Pox_A12 PF04651.8 CDI86955.1 - 0.61 10.1 16.6 0.75 9.8 11.5 1.2 1 0 0 1 1 1 0 Poxvirus A12 protein Macoilin PF09726.4 CDI86955.1 - 1.3 7.2 17.5 1.8 6.7 12.2 1.2 1 0 0 1 1 1 0 Transmembrane protein PCNP PF15473.1 CDI86955.1 - 1.4 9.1 14.3 1.6 9.0 9.9 1.1 1 0 0 1 1 1 0 PEST, proteolytic signal-containing nuclear protein family MACPF PF01823.14 CDI86955.1 - 2 8.0 13.9 2.4 7.8 9.7 1.2 1 0 0 1 1 1 0 MAC/Perforin domain CAML PF14963.1 CDI86955.1 - 2.5 7.3 9.7 2.6 7.3 6.8 1.1 1 0 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand XAP5 PF04921.9 CDI86955.1 - 3.3 7.1 13.8 4.1 6.8 9.6 1.0 1 0 0 1 1 1 0 XAP5, circadian clock regulator NAM-associated PF14303.1 CDI86955.1 - 3.4 7.9 21.9 4.3 7.6 15.2 1.1 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain RAP1 PF07218.6 CDI86955.1 - 4 5.3 8.8 4.2 5.3 6.1 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DUF572 PF04502.8 CDI86955.1 - 4.3 6.4 21.8 4.6 6.3 15.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) DNA_pol_viral_N PF00242.12 CDI86955.1 - 7.3 5.5 22.6 9.2 5.1 15.7 1.2 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain FAM60A PF15396.1 CDI86955.1 - 8.3 6.0 20.6 9.8 5.8 14.3 1.1 1 0 0 1 1 1 0 Protein Family FAM60A DUF4614 PF15391.1 CDI86956.1 - 0.013 15.2 23.3 0.025 14.3 5.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4614) Macoilin PF09726.4 CDI86956.1 - 0.013 13.7 21.9 0.019 13.3 15.2 1.2 1 0 0 1 1 1 0 Transmembrane protein AKAP2_C PF15304.1 CDI86956.1 - 0.72 9.3 21.5 2.4 7.6 8.9 2.2 2 0 0 2 2 2 0 A-kinase anchor protein 2 C-terminus Cwf_Cwc_15 PF04889.7 CDI86956.1 - 0.79 9.3 9.2 4.7 6.8 3.8 2.2 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein DUF508 PF04370.7 CDI86956.1 - 1.6 8.3 23.6 0.34 10.5 4.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF508) CDC45 PF02724.9 CDI86956.1 - 2.2 6.2 10.4 0.3 9.0 3.3 1.9 2 0 0 2 2 2 0 CDC45-like protein SOBP PF15279.1 CDI86956.1 - 2.3 8.4 13.6 4.6 7.5 0.6 2.2 2 0 0 2 2 2 0 Sine oculis-binding protein DUF755 PF05501.6 CDI86957.1 - 0.0055 16.7 31.6 0.0055 16.7 21.9 16.0 14 3 1 15 15 15 3 Domain of unknown function (DUF755) Utp11 PF03998.8 CDI86957.1 - 0.006 16.4 3.3 0.006 16.4 2.3 5.8 5 0 0 5 5 5 1 Utp11 protein Potyvirid-P3 PF13608.1 CDI86958.1 - 0.24 10.4 16.3 0.27 10.3 11.3 1.0 1 0 0 1 1 1 0 Protein P3 of Potyviral polyprotein DUF755 PF05501.6 CDI86959.1 - 0.0001 22.3 15.6 0.0001 22.3 10.8 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF755) AF-4 PF05110.8 CDI86959.1 - 0.004 15.1 8.0 0.0044 14.9 5.6 1.2 1 0 0 1 1 1 1 AF-4 proto-oncoprotein Mlf1IP PF10248.4 CDI86959.1 - 0.006 16.2 3.3 0.01 15.4 2.3 1.4 1 0 0 1 1 1 1 Myelodysplasia-myeloid leukemia factor 1-interacting protein Ribosomal_60s PF00428.14 CDI86959.1 - 0.026 14.8 2.0 0.045 14.1 1.4 1.3 1 0 0 1 1 1 0 60s Acidic ribosomal protein DUF1427 PF07235.6 CDI86959.1 - 0.032 14.3 0.4 0.032 14.3 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1427) Myco_19_kDa PF05481.7 CDI86959.1 - 0.039 13.7 1.3 0.039 13.7 0.9 1.5 2 0 0 2 2 2 0 Mycobacterium 19 kDa lipoprotein antigen DUF3115 PF11312.3 CDI86959.1 - 0.076 11.8 0.5 0.13 11.1 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3115) Hid1 PF12722.2 CDI86959.1 - 0.92 7.1 8.3 1 6.9 5.7 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Med15 PF09606.5 CDI86959.1 - 2.8 6.0 44.9 4.3 5.4 31.1 1.3 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal BRF1 PF07741.8 CDI86959.1 - 3.8 7.7 7.9 1.1 9.5 2.3 2.1 2 0 0 2 2 2 0 Brf1-like TBP-binding domain Neur_chan_memb PF02932.11 CDI86959.1 - 4.2 7.1 11.7 2.1 8.1 6.7 1.4 1 1 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region YfhO PF09586.5 CDI86959.1 - 4.4 5.1 8.9 5.3 4.9 6.1 1.1 1 0 0 1 1 1 0 Bacterial membrane protein YfhO Urb2 PF10441.4 CDI86959.1 - 9.1 5.8 10.3 0.63 9.6 3.5 1.6 2 0 0 2 2 2 0 Urb2/Npa2 family DUF3357 PF11837.3 CDI86961.1 - 0.066 13.0 0.6 0.8 9.5 0.0 2.4 2 1 1 3 3 3 0 Domain of unknown function (DUF3357) Mg_trans_NIPA PF05653.9 CDI86962.1 - 1e-05 24.6 2.6 1.4e-05 24.1 1.8 1.1 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.15 CDI86962.1 - 0.021 14.8 1.9 0.021 14.8 1.3 3.2 4 0 0 4 4 4 0 EamA-like transporter family SR-25 PF10500.4 CDI86962.1 - 3 7.2 13.6 0.023 14.1 3.8 1.6 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein MIP-T3 PF10243.4 CDI86964.1 - 8.8e-07 27.7 42.2 1.1e-06 27.4 29.3 1.0 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 Dicty_REP PF05086.7 CDI86964.1 - 0.049 11.4 31.3 0.072 10.8 21.7 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein NTP_transf_2 PF01909.18 CDI86964.1 - 0.056 13.7 0.0 0.078 13.3 0.0 1.2 1 0 0 1 1 1 0 Nucleotidyltransferase domain DUF1510 PF07423.6 CDI86964.1 - 1.7 7.9 60.4 2.3 7.5 25.7 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) Spore_coat_CotO PF14153.1 CDI86964.1 - 1.7 8.0 52.0 0.4 10.1 27.2 2.2 2 0 0 2 2 2 0 Spore coat protein CotO CRT10 PF08728.5 CDI86964.1 - 4.9 5.0 27.9 7 4.4 19.4 1.1 1 0 0 1 1 1 0 CRT10 RBFA PF02033.13 CDI86965.1 - 3.5e-10 39.8 0.1 8.6e-10 38.5 0.0 1.7 2 0 0 2 2 2 1 Ribosome-binding factor A ACT PF01842.20 CDI86965.1 - 0.025 14.0 0.0 0.22 11.0 0.0 2.2 2 0 0 2 2 2 0 ACT domain Oxidored_q6 PF01058.17 CDI86967.1 - 0.0075 15.8 0.6 0.008 15.7 0.4 1.1 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit Ribosomal_60s PF00428.14 CDI86967.1 - 0.014 15.8 6.3 0.014 15.8 4.3 1.8 2 0 0 2 2 2 0 60s Acidic ribosomal protein SAF_2 PF13144.1 CDI86967.1 - 0.057 12.9 0.2 0.071 12.5 0.1 1.1 1 0 0 1 1 1 0 SAF-like TcdA_TcdB_pore PF12920.2 CDI86967.1 - 0.18 9.6 2.4 0.21 9.4 1.6 1.0 1 0 0 1 1 1 0 TcdA/TcdB pore forming domain DUF3138 PF11336.3 CDI86967.1 - 0.35 9.0 7.4 0.36 8.9 5.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) DUF3123 PF11321.3 CDI86967.1 - 9.3 6.5 8.6 15 5.8 5.7 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3123) GET2 PF08690.5 CDI86968.1 - 0.85 8.7 14.2 1.1 8.3 9.8 1.1 1 0 0 1 1 1 0 GET complex subunit GET2 Lipoprotein_10 PF03202.8 CDI86968.1 - 9.1 6.2 10.1 0.81 9.7 0.5 2.7 2 1 1 3 3 3 0 Putative mycoplasma lipoprotein, C-terminal region RNA_lig_T4_1 PF09511.5 CDI86970.1 - 0.00014 21.4 0.2 0.00055 19.4 0.0 2.0 2 0 0 2 2 2 1 RNA ligase AAA_18 PF13238.1 CDI86970.1 - 0.36 11.1 0.4 22 5.3 0.1 2.9 2 0 0 2 2 2 0 AAA domain KH_1 PF00013.24 CDI86971.1 - 3e-07 29.9 0.0 8.3e-07 28.5 0.0 1.8 2 0 0 2 2 2 1 KH domain KH_3 PF13014.1 CDI86971.1 - 8.6e-05 22.0 0.0 0.00017 21.1 0.0 1.5 1 0 0 1 1 1 1 KH domain Med15 PF09606.5 CDI86971.1 - 0.00077 17.8 20.6 0.00077 17.8 14.3 4.4 3 1 1 5 5 5 1 ARC105 or Med15 subunit of Mediator complex non-fungal DUF912 PF06024.7 CDI86971.1 - 0.026 14.5 1.2 0.026 14.5 0.8 5.4 6 1 0 6 6 6 0 Nucleopolyhedrovirus protein of unknown function (DUF912) KH_2 PF07650.12 CDI86971.1 - 0.15 11.6 0.0 0.27 10.8 0.0 1.3 1 0 0 1 1 1 0 KH domain UPF0233 PF06781.7 CDI86971.1 - 0.58 9.8 3.3 0.86 9.2 0.1 2.9 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0233) DUF2227 PF09988.4 CDI86971.1 - 1.5 8.4 3.8 1.2 8.7 0.4 2.5 2 0 0 2 2 2 0 Uncharacterized metal-binding protein (DUF2227) Med15 PF09606.5 CDI86972.1 - 0.0001 20.7 4.3 0.0001 20.7 3.0 2.6 3 0 0 3 3 3 1 ARC105 or Med15 subunit of Mediator complex non-fungal OmpH PF03938.9 CDI86972.1 - 0.0027 17.6 0.6 0.0027 17.6 0.4 3.0 2 1 0 2 2 2 1 Outer membrane protein (OmpH-like) SR-25 PF10500.4 CDI86972.1 - 0.0037 16.7 69.3 0.018 14.5 10.6 4.2 4 0 0 4 4 4 3 Nuclear RNA-splicing-associated protein DAGK_cat PF00781.19 CDI86972.1 - 0.026 13.9 0.0 0.07 12.5 0.0 1.7 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain NAD_kinase PF01513.16 CDI86972.1 - 0.054 12.2 0.0 0.09 11.5 0.0 1.3 1 0 0 1 1 1 0 ATP-NAD kinase Spt20 PF12090.3 CDI86972.1 - 0.15 11.4 0.1 0.15 11.4 0.1 3.2 2 1 0 2 2 2 0 Spt20 family SAPS PF04499.10 CDI86972.1 - 5 5.6 13.2 38 2.7 9.3 2.0 1 1 0 1 1 1 0 SIT4 phosphatase-associated protein SelP_N PF04592.9 CDI86972.1 - 8.1 5.7 19.6 5.3 6.3 10.9 2.2 2 0 0 2 2 2 0 Selenoprotein P, N terminal region IncA PF04156.9 CDI86975.1 - 0.0012 18.4 9.9 0.0012 18.4 6.8 2.4 2 1 0 2 2 2 1 IncA protein ORC6 PF05460.8 CDI86975.1 - 0.033 13.3 9.1 0.043 12.9 6.3 1.0 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) TFIIA PF03153.8 CDI86975.1 - 0.85 9.4 36.8 1 9.1 25.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF966 PF06136.8 CDI86975.1 - 1.1 8.5 15.3 1.8 7.9 10.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Pyrid_oxidase_2 PF13883.1 CDI86975.1 - 2.8 7.6 7.2 0.23 11.2 1.1 1.8 1 1 0 2 2 2 0 Pyridoxamine 5'-phosphate oxidase eIF-3_zeta PF05091.7 CDI86976.1 - 1.8 7.0 19.7 2.1 6.8 13.6 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) AAA_23 PF13476.1 CDI86976.1 - 3 8.1 21.5 3.7 7.8 14.9 1.2 1 0 0 1 1 1 0 AAA domain Apt1 PF10351.4 CDI86976.1 - 5 5.8 18.3 6.2 5.5 12.7 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain IncA PF04156.9 CDI86977.1 - 0.00014 21.5 12.7 0.00014 21.5 8.8 5.2 5 1 0 5 5 5 1 IncA protein DUF1510 PF07423.6 CDI86977.1 - 0.0019 17.5 4.5 0.0019 17.5 3.1 3.5 2 1 0 2 2 2 1 Protein of unknown function (DUF1510) EphA2_TM PF14575.1 CDI86977.1 - 0.0021 18.3 1.4 0.0021 18.3 1.0 5.1 5 1 1 6 6 6 1 Ephrin type-A receptor 2 transmembrane domain FAM176 PF14851.1 CDI86977.1 - 0.0023 17.6 0.3 0.0023 17.6 0.2 4.3 2 1 2 4 4 4 1 FAM176 family DUF3260 PF11658.3 CDI86977.1 - 0.0038 15.4 5.0 0.0038 15.4 3.4 3.9 2 1 1 3 3 3 1 Protein of unknown function (DUF3260) SpoIIIAH PF12685.2 CDI86977.1 - 0.0049 16.3 7.6 0.0049 16.3 5.3 5.6 2 2 1 3 3 3 1 SpoIIIAH-like protein Ctr PF04145.10 CDI86977.1 - 0.011 15.7 1.0 0.011 15.7 0.7 5.0 2 1 0 2 2 2 0 Ctr copper transporter family DUF3357 PF11837.3 CDI86977.1 - 0.012 15.4 1.6 0.012 15.4 1.1 5.2 6 0 0 6 6 6 0 Domain of unknown function (DUF3357) OSTbeta PF15048.1 CDI86977.1 - 0.013 15.5 2.3 0.013 15.5 1.6 4.4 2 1 2 4 4 4 0 Organic solute transporter subunit beta protein DUF843 PF05814.6 CDI86977.1 - 0.75 9.6 2.9 1.9 8.3 2.0 1.7 1 0 0 1 1 1 0 Baculovirus protein of unknown function (DUF843) SR-25 PF10500.4 CDI86978.1 - 0.0073 15.8 3.0 0.0073 15.8 2.1 10.0 7 2 2 9 9 9 4 Nuclear RNA-splicing-associated protein NicO PF03824.11 CDI86980.1 - 0.11 11.7 7.2 0.021 14.1 1.3 2.0 2 0 0 2 2 2 0 High-affinity nickel-transport protein DUF4367 PF14285.1 CDI86980.1 - 0.56 9.5 6.5 19 4.5 3.5 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4367) DUF3792 PF12670.2 CDI86980.1 - 2.6 7.9 5.9 0.35 10.7 1.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3792) OPT PF03169.10 CDI86980.1 - 7.1 4.9 10.0 4.3 5.6 0.3 2.2 2 0 0 2 2 2 0 OPT oligopeptide transporter protein Gag_spuma PF03276.9 CDI86981.1 - 9.2e-05 20.9 31.5 0.00012 20.6 21.8 1.3 1 0 0 1 1 1 1 Spumavirus gag protein SieB PF14163.1 CDI86981.1 - 0.0052 16.3 1.1 0.01 15.4 0.5 1.6 1 1 0 1 1 1 1 Superinfection exclusion protein B Med15 PF09606.5 CDI86981.1 - 0.016 13.4 64.9 0.019 13.1 45.0 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal GAGA_bind PF06217.7 CDI86981.1 - 0.017 15.1 18.9 0.02 14.9 13.1 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family PAT1 PF09770.4 CDI86981.1 - 0.039 12.2 47.8 0.039 12.2 33.1 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SAGA-Tad1 PF12767.2 CDI86981.1 - 0.082 12.5 24.8 0.11 12.1 17.2 1.1 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit Hom_end_hint PF05203.11 CDI86981.1 - 0.64 9.7 14.6 0.84 9.3 10.1 1.2 1 0 0 1 1 1 0 Hom_end-associated Hint Herpes_TAF50 PF03326.8 CDI86981.1 - 0.67 8.8 27.6 0.77 8.6 19.2 1.1 1 0 0 1 1 1 0 Herpesvirus transcription activation factor (transactivator) DUF2146 PF10220.4 CDI86981.1 - 0.76 7.6 17.1 0.96 7.3 11.9 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2146) Neur_chan_memb PF02932.11 CDI86981.1 - 1 9.2 16.8 1.7 8.4 11.7 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Herpes_UL87 PF03043.9 CDI86981.1 - 1.2 7.4 10.7 1.4 7.1 7.4 1.2 1 0 0 1 1 1 0 Herpesvirus UL87 family UNC-79 PF14776.1 CDI86981.1 - 1.7 6.9 11.1 2.2 6.5 7.7 1.1 1 0 0 1 1 1 0 Cation-channel complex subunit UNC-79 Pyr_redox_2 PF07992.9 CDI86981.1 - 2 8.2 4.2 6.8 6.5 2.9 1.8 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DUF763 PF05559.6 CDI86981.1 - 2 7.2 11.8 2.5 6.9 8.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF763) PA26 PF04636.8 CDI86981.1 - 2.8 6.5 13.7 3.6 6.1 9.5 1.2 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) BNR_3 PF13859.1 CDI86981.1 - 5.4 5.9 10.8 7.1 5.5 7.5 1.1 1 0 0 1 1 1 0 BNR repeat-like domain FLO_LFY PF01698.11 CDI86981.1 - 6.9 5.4 23.8 9.9 4.8 16.5 1.2 1 0 0 1 1 1 0 Floricaula / Leafy protein 2-oxoacid_dh PF00198.18 CDI86984.1 - 1.7e-65 220.5 0.2 4.6e-25 88.2 0.0 3.0 1 1 2 3 3 3 3 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Peptidase_S49_N PF08496.5 CDI86985.1 - 0.034 13.9 13.6 0.052 13.3 9.4 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Arena_glycoprot PF00798.13 CDI86985.1 - 0.059 11.7 4.2 0.074 11.4 2.9 1.1 1 0 0 1 1 1 0 Arenavirus glycoprotein Herpes_UL87 PF03043.9 CDI86985.1 - 0.24 9.7 5.0 0.28 9.5 3.5 1.2 1 0 0 1 1 1 0 Herpesvirus UL87 family Draxin PF15550.1 CDI86985.1 - 0.32 10.5 16.1 0.44 10.1 11.2 1.2 1 0 0 1 1 1 0 Draxin Sec62 PF03839.11 CDI86985.1 - 0.56 9.5 7.7 0.81 9.0 5.3 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 Atg14 PF10186.4 CDI86985.1 - 0.59 9.0 23.5 1.1 8.2 16.3 1.4 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 CT47 PF15623.1 CDI86985.1 - 1.1 9.0 28.6 1.7 8.3 19.8 1.2 1 0 0 1 1 1 0 Cancer/testis gene family 47 DUF342 PF03961.8 CDI86985.1 - 3.4 5.9 13.4 4.4 5.6 9.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Zea_mays_MuDR PF05928.6 CDI86985.1 - 3.4 7.0 13.6 4.9 6.5 9.5 1.2 1 0 0 1 1 1 0 Zea mays MURB-like protein (MuDR) GAGA_bind PF06217.7 CDI86985.1 - 6.1 6.7 16.0 9.2 6.1 11.1 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family V_ATPase_I PF01496.14 CDI86985.1 - 6.1 4.5 11.4 7.6 4.2 7.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family HlyD_2 PF12700.2 CDI86985.1 - 7.8 5.5 17.1 12 4.8 11.9 1.4 1 0 0 1 1 1 0 HlyD family secretion protein 5_nucleotid PF05761.9 CDI86985.1 - 7.9 4.8 12.3 10 4.4 8.5 1.1 1 0 0 1 1 1 0 5' nucleotidase family MRP-S31 PF15433.1 CDI86985.1 - 8.7 5.6 23.6 13 5.1 16.3 1.2 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 PAT1 PF09770.4 CDI86985.1 - 9.4 4.3 51.8 11 4.1 35.9 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Flavi_NS2A PF01005.14 CDI86986.1 - 0.024 13.9 0.2 0.059 12.6 0.1 1.6 1 0 0 1 1 1 0 Flavivirus non-structural protein NS2A Fumble PF03630.9 CDI86987.1 - 1.9e-62 211.1 4.5 3.9e-59 200.2 0.0 2.5 3 0 0 3 3 3 2 Fumble CIAPIN1 PF05093.8 CDI86987.1 - 0.43 10.6 4.2 1.9 8.6 1.6 2.5 2 0 0 2 2 2 0 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis MRP-S31 PF15433.1 CDI86993.1 - 0.025 13.9 4.0 0.033 13.6 2.7 1.2 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 TFIIA PF03153.8 CDI86993.1 - 0.57 10.0 15.6 0.9 9.3 10.8 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Med15 PF09606.5 CDI86993.1 - 2.1 6.4 28.2 2.7 6.0 19.5 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Suf PF05843.9 CDI86993.1 - 4.1 7.0 8.6 5.8 6.5 6.0 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) PAT1 PF09770.4 CDI86993.1 - 4.3 5.4 19.9 5.3 5.1 13.8 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Tir_receptor_N PF07490.6 CDI86995.1 - 0.00063 19.4 2.7 0.00063 19.4 1.9 2.6 3 0 0 3 3 3 1 Translocated intimin receptor (Tir) N-terminus CbiM PF01891.11 CDI86995.1 - 0.042 13.4 5.9 0.84 9.1 0.0 2.1 2 0 0 2 2 2 0 Cobalt uptake substrate-specific transmembrane region AAA_23 PF13476.1 CDI86995.1 - 0.067 13.5 20.2 0.36 11.1 9.1 2.1 2 0 0 2 2 2 0 AAA domain Shadoo PF14999.1 CDI86995.1 - 0.42 10.4 20.1 0.23 11.3 2.2 2.8 2 0 0 2 2 2 0 Shadow of prion protein, neuroprotective DUF2232 PF09991.4 CDI86995.1 - 0.43 9.5 9.0 0.97 8.3 6.3 1.5 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) DUF4367 PF14285.1 CDI86995.1 - 0.76 9.0 9.2 7.8 5.7 3.8 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4367) DUF3573 PF12097.3 CDI86995.1 - 4.9 5.6 19.8 0.045 12.3 6.9 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3573) Med15 PF09606.5 CDI86995.1 - 5.7 5.0 66.7 9.4 4.2 46.2 1.3 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Virul_fac_BrkB PF03631.10 CDI86995.1 - 9.3 5.5 13.5 2.3 7.5 7.0 1.7 2 0 0 2 2 2 0 Virulence factor BrkB Dehydrin PF00257.14 CDI86996.1 - 0.39 11.0 0.0 0.39 11.0 0.0 11.5 7 4 1 8 8 8 0 Dehydrin eIF-3c_N PF05470.7 CDI86997.1 - 1.3e-130 436.2 6.0 2.1e-130 435.6 4.1 1.3 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.22 CDI86997.1 - 3.3e-13 49.8 0.0 1.8e-12 47.4 0.0 2.4 1 0 0 1 1 1 1 PCI domain DNA_photolyase PF00875.13 CDI86998.1 - 7.3e-10 38.8 0.6 1e-09 38.3 0.4 1.2 1 0 0 1 1 1 1 DNA photolyase Myosin_head PF00063.16 CDI86999.1 - 1.4e-22 79.6 0.0 1.5e-22 79.5 0.0 1.0 1 0 0 1 1 1 1 Myosin head (motor domain) DUF3157 PF11355.3 CDI87000.1 - 6.1 6.0 6.6 6.1 6.0 4.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3157) Peroxin-3 PF04882.7 CDI87001.1 - 1.9e-10 40.0 19.0 1.9e-10 40.0 13.2 3.6 1 1 1 2 2 2 1 Peroxin-3 Med15 PF09606.5 CDI87002.1 - 0.00013 20.3 41.8 0.00016 20.0 29.0 1.0 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal PBP1_TM PF14812.1 CDI87002.1 - 0.015 15.6 4.7 0.021 15.1 3.2 1.2 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal SpoVR PF04293.8 CDI87002.1 - 0.029 12.7 6.3 0.032 12.6 4.4 1.1 1 0 0 1 1 1 0 SpoVR like protein SprA-related PF12118.3 CDI87002.1 - 0.037 13.3 41.7 0.048 12.9 28.9 1.1 1 0 0 1 1 1 0 SprA-related family Serinc PF03348.10 CDI87002.1 - 0.039 12.6 10.6 0.048 12.3 7.4 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) RR_TM4-6 PF06459.7 CDI87002.1 - 0.057 13.3 14.2 0.069 13.0 9.8 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CDC45 PF02724.9 CDI87002.1 - 0.061 11.3 13.3 0.076 11.0 9.2 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF1183 PF06682.7 CDI87002.1 - 0.07 12.7 10.0 0.084 12.4 6.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) Raftlin PF15250.1 CDI87002.1 - 0.087 11.3 12.7 0.095 11.2 8.8 1.1 1 0 0 1 1 1 0 Raftlin SAGA-Tad1 PF12767.2 CDI87002.1 - 0.19 11.3 16.8 0.22 11.1 11.7 1.1 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit FAM60A PF15396.1 CDI87002.1 - 0.2 11.3 11.5 0.23 11.2 8.0 1.3 1 0 0 1 1 1 0 Protein Family FAM60A SID-1_RNA_chan PF13965.1 CDI87002.1 - 0.27 9.3 5.5 0.29 9.2 3.8 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 NPR3 PF03666.8 CDI87002.1 - 0.47 8.9 14.5 0.65 8.4 10.0 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF605 PF04652.11 CDI87002.1 - 0.54 9.5 24.6 0.67 9.2 17.1 1.1 1 0 0 1 1 1 0 Vta1 like DUF1510 PF07423.6 CDI87002.1 - 0.59 9.4 18.5 0.55 9.5 12.2 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1510) Peptidase_S49_N PF08496.5 CDI87002.1 - 0.69 9.6 12.5 1.1 8.9 8.5 1.5 1 1 0 1 1 1 0 Peptidase family S49 N-terminal DUF4220 PF13968.1 CDI87002.1 - 0.9 8.5 5.5 1.1 8.3 3.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4220) Parvo_coat PF00740.13 CDI87002.1 - 1 8.2 20.4 1.2 7.9 14.1 1.0 1 0 0 1 1 1 0 Parvovirus coat protein VP2 HemX PF04375.9 CDI87002.1 - 1.1 7.8 34.9 1.3 7.5 24.2 1.0 1 0 0 1 1 1 0 HemX CAF-1_p150 PF11600.3 CDI87002.1 - 1.1 8.6 21.4 1.7 7.9 14.9 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Sec62 PF03839.11 CDI87002.1 - 1.2 8.4 6.5 1.5 8.1 4.5 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 FLO_LFY PF01698.11 CDI87002.1 - 1.3 7.8 14.9 1.7 7.4 10.3 1.3 1 0 0 1 1 1 0 Floricaula / Leafy protein Glypican PF01153.14 CDI87002.1 - 1.5 7.3 12.9 0.5 8.9 7.3 1.4 1 1 0 1 1 1 0 Glypican Hid1 PF12722.2 CDI87002.1 - 1.7 6.2 15.7 1.7 6.2 10.9 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Herpes_DNAp_acc PF04929.7 CDI87002.1 - 1.7 7.4 14.2 2.1 7.2 9.9 1.2 1 0 0 1 1 1 0 Herpes DNA replication accessory factor TFIIA PF03153.8 CDI87002.1 - 2.3 8.0 38.7 3.3 7.4 26.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PPP4R2 PF09184.6 CDI87002.1 - 2.5 7.5 12.0 2.8 7.3 8.3 1.1 1 0 0 1 1 1 0 PPP4R2 Neur_chan_memb PF02932.11 CDI87002.1 - 2.6 7.8 10.2 3.1 7.6 7.0 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF4330 PF14221.1 CDI87002.1 - 2.7 7.8 5.4 1.2 9.0 2.1 1.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4330) CDK5_activator PF03261.10 CDI87002.1 - 3 7.0 13.9 3.9 6.7 9.6 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein CDC27 PF09507.5 CDI87002.1 - 3.3 6.8 23.9 4.2 6.4 16.5 1.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 MRP-S31 PF15433.1 CDI87002.1 - 3.5 6.9 22.4 4.5 6.6 15.5 1.1 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 FAM217 PF15344.1 CDI87002.1 - 5.3 6.5 19.8 6.6 6.2 13.7 1.1 1 0 0 1 1 1 0 FAM217 family SOBP PF15279.1 CDI87002.1 - 5.7 7.2 17.5 6.6 7.0 12.1 1.0 1 0 0 1 1 1 0 Sine oculis-binding protein Presenilin PF01080.12 CDI87002.1 - 7.2 5.3 17.2 12 4.6 11.9 1.3 1 0 0 1 1 1 0 Presenilin RED_N PF07808.8 CDI87002.1 - 7.8 5.6 17.0 14 4.8 11.8 1.4 1 0 0 1 1 1 0 RED-like protein N-terminal region Ndc1_Nup PF09531.5 CDI87002.1 - 9.2 4.5 14.7 10 4.3 10.2 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup IncA PF04156.9 CDI87004.1 - 0.0038 16.8 14.0 0.0038 16.8 9.7 2.1 2 0 0 2 2 2 1 IncA protein Ribosomal_60s PF00428.14 CDI87004.1 - 0.028 14.8 7.5 0.028 14.8 5.2 3.3 2 1 0 2 2 1 0 60s Acidic ribosomal protein CAF-1_p150 PF11600.3 CDI87004.1 - 0.03 13.6 18.5 0.048 13.0 12.8 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal SOBP PF15279.1 CDI87004.1 - 0.048 14.0 20.7 0.061 13.7 14.4 1.0 1 0 0 1 1 1 0 Sine oculis-binding protein GPCR_chapero_1 PF11904.3 CDI87004.1 - 0.16 11.0 8.3 0.23 10.5 5.8 1.3 1 0 0 1 1 1 0 GPCR-chaperone THRAP3_BCLAF1 PF15440.1 CDI87004.1 - 0.29 9.7 19.5 0.37 9.4 13.5 1.0 1 0 0 1 1 1 0 THRAP3/BCLAF1 family Presenilin PF01080.12 CDI87004.1 - 0.42 9.3 11.4 0.49 9.1 7.9 1.3 1 0 0 1 1 1 0 Presenilin Macoilin PF09726.4 CDI87004.1 - 0.74 8.0 27.5 0.96 7.6 19.1 1.1 1 0 0 1 1 1 0 Transmembrane protein AAA_23 PF13476.1 CDI87004.1 - 1 9.6 8.7 1.4 9.2 6.0 1.2 1 0 0 1 1 1 0 AAA domain PAT1 PF09770.4 CDI87004.1 - 1.1 7.3 34.4 1.2 7.2 23.9 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Utp14 PF04615.8 CDI87004.1 - 1.8 6.6 19.5 1.9 6.5 13.5 1.0 1 0 0 1 1 1 0 Utp14 protein Peptidase_S46 PF10459.4 CDI87004.1 - 2.7 6.3 19.8 3.1 6.1 13.8 1.0 1 0 0 1 1 1 0 Peptidase S46 Ndc1_Nup PF09531.5 CDI87004.1 - 5 5.4 18.4 5.7 5.2 12.7 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF4551 PF15087.1 CDI87004.1 - 5.8 5.1 19.0 7 4.8 13.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Raftlin PF15250.1 CDI87004.1 - 8.8 4.7 14.2 13 4.1 9.9 1.2 1 0 0 1 1 1 0 Raftlin DUF755 PF05501.6 CDI87005.1 - 0.0065 16.5 14.9 0.0065 16.5 10.3 6.9 3 2 3 6 6 6 1 Domain of unknown function (DUF755) MIP-T3 PF10243.4 CDI87006.1 - 0.56 8.6 91.3 0.45 8.9 38.3 2.3 1 1 1 2 2 2 0 Microtubule-binding protein MIP-T3 RAP1 PF07218.6 CDI87006.1 - 0.72 7.8 7.2 1.6 6.7 5.0 1.6 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Ycf1 PF05758.7 CDI87008.1 - 0.012 13.4 38.5 0.026 12.2 20.6 2.1 2 0 0 2 2 2 0 Ycf1 SPX PF03105.14 CDI87008.1 - 0.026 14.3 34.9 1.2 8.8 20.9 2.2 2 0 0 2 2 2 0 SPX domain Parvo_coat PF00740.13 CDI87008.1 - 0.079 11.9 50.3 0.58 9.0 22.1 2.2 2 0 0 2 2 2 0 Parvovirus coat protein VP2 GAGA_bind PF06217.7 CDI87008.1 - 0.37 10.7 41.6 0.81 9.5 22.7 2.5 2 0 0 2 2 2 0 GAGA binding protein-like family DUF2802 PF10975.3 CDI87009.1 - 0.058 13.1 3.5 0.095 12.4 2.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2802) DUF3617 PF12276.3 CDI87009.1 - 0.063 12.7 0.4 0.063 12.7 0.3 3.7 3 1 0 3 3 3 0 Protein of unknown function (DUF3617) Sporozoite_P67 PF05642.6 CDI87009.1 - 5.3 4.7 6.3 5.2 4.8 4.4 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen SprA-related PF12118.3 CDI87010.1 - 0.00015 21.2 34.6 0.0002 20.8 24.0 1.1 1 0 0 1 1 1 1 SprA-related family Peptidase_S15 PF02129.13 CDI87010.1 - 0.019 14.3 3.7 0.022 14.1 2.6 1.2 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) PAT1 PF09770.4 CDI87010.1 - 0.02 13.1 26.2 0.023 12.9 18.1 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 BAF1_ABF1 PF04684.8 CDI87010.1 - 0.092 11.5 0.1 0.092 11.5 0.1 2.5 2 1 1 3 3 3 0 BAF1 / ABF1 chromatin reorganising factor TFIIA PF03153.8 CDI87010.1 - 0.12 12.2 25.7 0.17 11.7 17.8 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF605 PF04652.11 CDI87010.1 - 0.33 10.3 22.6 0.46 9.8 15.7 1.2 1 0 0 1 1 1 0 Vta1 like APH PF01636.18 CDI87010.1 - 0.53 9.9 5.4 0.75 9.4 3.7 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family TAT_signal PF10518.4 CDI87010.1 - 2.4 8.3 14.5 0.24 11.5 1.2 2.9 2 0 0 2 2 2 0 TAT (twin-arginine translocation) pathway signal sequence Slu7 PF11708.3 CDI87010.1 - 3.1 7.4 21.1 0.062 13.0 9.8 1.7 2 0 0 2 2 2 0 Pre-mRNA splicing Prp18-interacting factor DUF3573 PF12097.3 CDI87010.1 - 3.2 6.2 5.6 4.6 5.7 3.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) Ycf1 PF05758.7 CDI87010.1 - 6.3 4.3 12.9 6.5 4.3 8.9 1.1 1 0 0 1 1 1 0 Ycf1 SOG2 PF10428.4 CDI87011.1 - 1.2 7.7 7.8 1.2 7.7 5.4 1.0 1 0 0 1 1 1 0 RAM signalling pathway protein Pol_alpha_B_N PF08418.5 CDI87011.1 - 1.5 8.2 9.5 1.5 8.2 6.6 1.0 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal Actin PF00022.14 CDI87012.1 - 2.9e-05 22.6 0.0 0.0048 15.3 0.0 2.6 2 1 0 2 2 2 2 Actin SR-25 PF10500.4 CDI87013.1 - 2.4e-05 23.9 19.1 2.4e-05 23.9 13.2 4.7 5 0 0 5 5 5 1 Nuclear RNA-splicing-associated protein Zip PF02535.17 CDI87013.1 - 4.5e-05 22.6 13.1 0.0023 16.9 1.1 2.6 2 0 0 2 2 2 2 ZIP Zinc transporter 60KD_IMP PF02096.15 CDI87013.1 - 0.075 12.6 0.2 0.075 12.6 0.1 5.5 3 2 2 5 5 5 0 60Kd inner membrane protein Hid1 PF12722.2 CDI87013.1 - 3.5 5.1 43.1 0.0039 14.9 9.4 2.3 2 0 0 2 2 2 0 High-temperature-induced dauer-formation protein Plasmodium_Vir PF05795.6 CDI87013.1 - 9.9 5.2 15.6 10 5.1 0.9 3.1 2 1 0 2 2 2 0 Plasmodium vivax Vir protein RNA_pol_Rpb1_R PF05001.8 CDI87014.1 - 7.5e-05 22.5 27.1 0.0021 17.9 7.6 18.3 9 4 6 16 16 16 11 RNA polymerase Rpb1 C-terminal repeat PIG-H PF10181.4 CDI87015.1 - 1.6e-11 43.6 0.2 2.5e-11 43.0 0.1 1.3 1 0 0 1 1 1 1 GPI-GlcNAc transferase complex, PIG-H component Med15 PF09606.5 CDI87015.1 - 0.0037 15.5 80.2 0.0046 15.2 55.6 1.1 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal IncA PF04156.9 CDI87015.1 - 0.032 13.8 42.6 0.38 10.3 29.6 2.0 1 1 0 1 1 1 0 IncA protein Hid1 PF12722.2 CDI87015.1 - 0.52 7.9 27.4 0.66 7.5 19.0 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein YjgP_YjgQ PF03739.9 CDI87015.1 - 1.2 7.7 6.1 1.7 7.2 4.3 1.3 1 0 0 1 1 1 0 Predicted permease YjgP/YjgQ family Anoctamin PF04547.7 CDI87015.1 - 1.9 7.0 16.9 0.16 10.5 0.6 2.1 2 0 0 2 2 2 0 Calcium-activated chloride channel Nucleoside_tran PF01733.13 CDI87015.1 - 3.3 6.7 6.6 2.9 6.9 1.1 2.1 2 0 0 2 2 2 0 Nucleoside transporter DcuC PF03606.10 CDI87015.1 - 6.8 4.7 13.7 1.7 6.8 5.4 2.1 2 0 0 2 2 2 0 C4-dicarboxylate anaerobic carrier CDC27 PF09507.5 CDI87015.1 - 7.4 5.6 34.7 10 5.1 24.0 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 DUF4220 PF13968.1 CDI87016.1 - 0.023 13.8 1.0 0.025 13.7 0.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4220) DUF3260 PF11658.3 CDI87016.1 - 0.025 12.7 6.1 0.028 12.5 4.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3260) ATG22 PF11700.3 CDI87016.1 - 0.037 12.4 0.2 0.049 12.1 0.1 1.2 1 0 0 1 1 1 0 Vacuole effluxer Atg22 like Peptidase_U57 PF05582.7 CDI87016.1 - 0.13 11.1 5.0 0.16 10.9 3.5 1.0 1 0 0 1 1 1 0 YabG peptidase U57 HutD PF05962.6 CDI87016.1 - 0.23 11.1 4.3 0.29 10.8 3.0 1.1 1 0 0 1 1 1 0 HutD DUF4131 PF13567.1 CDI87016.1 - 1.1 8.6 13.6 2.2 7.6 9.4 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4131) Afi1 PF07792.7 CDI87016.1 - 1.2 9.0 9.9 1.6 8.7 6.8 1.2 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking PRA1 PF03208.14 CDI87016.1 - 5.8 6.2 7.9 11 5.3 5.5 1.6 1 1 0 1 1 1 0 PRA1 family protein SR-25 PF10500.4 CDI87017.1 - 0.0028 17.1 7.2 0.0028 17.1 5.0 4.9 2 2 1 4 4 4 1 Nuclear RNA-splicing-associated protein Dehydrin PF00257.14 CDI87017.1 - 0.019 15.2 4.7 0.019 15.2 3.2 3.0 3 0 0 3 3 3 0 Dehydrin Band_3_cyto PF07565.8 CDI87017.1 - 6.3 6.2 15.9 0.56 9.6 0.8 2.4 3 0 0 3 3 3 0 Band 3 cytoplasmic domain K_channel_TID PF07941.6 CDI87020.1 - 0.017 15.3 9.0 0.017 15.3 6.3 7.8 4 2 2 6 6 4 0 Potassium channel Kv1.4 tandem inactivation domain DUF3457 PF11939.3 CDI87020.1 - 0.049 13.1 0.1 0.049 13.1 0.1 4.3 3 1 0 3 3 2 0 Protein of unknown function (DUF3457) DUF3357 PF11837.3 CDI87020.1 - 0.13 12.1 0.1 0.13 12.1 0.0 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF3357) Pex24p PF06398.6 CDI87020.1 - 0.13 11.0 0.0 0.17 10.6 0.0 1.2 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin ABC2_membrane_2 PF12679.2 CDI87020.1 - 0.14 10.9 1.4 0.43 9.3 0.8 2.0 1 1 0 1 1 1 0 ABC-2 family transporter protein DUF2722 PF10846.3 CDI87020.1 - 0.16 10.9 6.5 0.02 13.9 1.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) 7tm_1 PF00001.16 CDI87020.1 - 0.21 10.6 0.0 0.39 9.8 0.0 1.4 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) YfhO PF09586.5 CDI87020.1 - 0.54 8.2 2.5 0.68 7.8 1.7 1.1 1 0 0 1 1 1 0 Bacterial membrane protein YfhO FAM165 PF14981.1 CDI87020.1 - 2.7 7.5 8.8 0.39 10.2 2.2 2.5 2 0 0 2 2 2 0 FAM165 family RAB3GAP2_N PF14655.1 CDI87020.1 - 4.1 6.3 9.6 0.11 11.4 1.5 2.0 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Spt20 PF12090.3 CDI87020.1 - 5.4 6.3 7.8 1.6 8.0 2.7 1.8 2 0 0 2 2 2 0 Spt20 family Dehydrin PF00257.14 CDI87021.1 - 0.1 12.9 0.0 0.1 12.9 0.0 12.5 9 3 0 9 9 9 0 Dehydrin TFIIA PF03153.8 CDI87022.1 - 0.27 11.1 33.9 0.35 10.6 23.5 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF2217 PF10265.4 CDI87022.1 - 0.87 8.2 24.5 1 8.0 17.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) SprA-related PF12118.3 CDI87022.1 - 0.99 8.6 54.5 0.49 9.6 28.8 2.0 2 0 0 2 2 2 0 SprA-related family AvrE PF11725.3 CDI87022.1 - 3.4 4.5 31.8 3.8 4.3 22.0 1.0 1 0 0 1 1 1 0 Pathogenicity factor CT47 PF15623.1 CDI87022.1 - 4.7 6.8 43.2 2 8.0 26.9 1.9 2 0 0 2 2 2 0 Cancer/testis gene family 47 Hid1 PF12722.2 CDI87022.1 - 9.3 3.7 36.4 13 3.2 25.2 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SR-25 PF10500.4 CDI87023.1 - 0.0018 17.8 2.9 0.0018 17.8 2.0 16.9 8 4 4 14 14 14 2 Nuclear RNA-splicing-associated protein DER1 PF04511.10 CDI87024.1 - 4.2e-09 36.1 0.0 7.3e-09 35.4 0.0 1.3 1 0 0 1 1 1 1 Der1-like family DUF755 PF05501.6 CDI87024.1 - 0.0041 17.1 33.7 0.0041 17.1 23.3 3.4 3 1 0 3 3 3 1 Domain of unknown function (DUF755) Activator_LAG-3 PF11498.3 CDI87025.1 - 0.00017 20.4 6.6 0.00017 20.4 4.6 7.7 5 3 1 6 6 6 2 Transcriptional activator LAG-3 E_Pc_C PF06752.7 CDI87025.1 - 0.0014 18.1 16.9 0.0014 18.1 11.7 12.4 8 4 2 10 10 10 1 Enhancer of Polycomb C-terminus Pkinase PF00069.20 CDI87026.1 - 2.8e-39 134.8 0.0 1.6e-37 129.0 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDI87026.1 - 7.6e-22 77.6 0.0 1e-21 77.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CDI87026.1 - 8.5e-09 34.7 0.0 1.4e-08 34.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 CDI87026.1 - 3.4e-05 23.7 0.1 0.00018 21.3 0.2 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 CDI87026.1 - 0.18 11.3 0.0 0.37 10.3 0.0 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase EXS PF03124.9 CDI87027.1 - 1 8.3 0.4 2.2 7.1 0.3 1.5 1 0 0 1 1 1 0 EXS family RNA_pol_Rpb1_2 PF00623.15 CDI87029.1 - 8.2e-14 51.8 9.3 1.1e-13 51.4 1.1 2.6 2 1 0 2 2 2 1 RNA polymerase Rpb1, domain 2 RskA PF10099.4 CDI87029.1 - 0.0043 16.8 5.6 0.0043 16.8 3.9 2.1 2 0 0 2 2 2 1 Anti-sigma-K factor rskA RAP1 PF07218.6 CDI87029.1 - 0.027 12.5 8.8 0.027 12.5 6.1 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) EphA2_TM PF14575.1 CDI87029.1 - 0.041 14.2 1.2 0.041 14.2 0.8 2.5 3 0 0 3 3 2 0 Ephrin type-A receptor 2 transmembrane domain CAF-1_p150 PF11600.3 CDI87029.1 - 0.12 11.7 31.9 0.019 14.3 13.2 2.1 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF572 PF04502.8 CDI87029.1 - 0.16 11.2 22.5 0.19 10.9 15.6 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) FHIPEP PF00771.15 CDI87029.1 - 0.18 10.0 8.4 0.018 13.4 1.9 1.8 2 0 0 2 2 2 0 FHIPEP family Peptidase_S49_N PF08496.5 CDI87029.1 - 0.23 11.2 15.6 0.21 11.3 0.3 2.3 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Ribosomal_60s PF00428.14 CDI87029.1 - 0.35 11.2 7.8 1.8 8.9 0.8 2.5 2 0 0 2 2 2 0 60s Acidic ribosomal protein eIF3g PF12353.3 CDI87029.1 - 0.54 10.1 12.1 0.2 11.5 4.2 2.4 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit G TMEM154 PF15102.1 CDI87029.1 - 0.63 9.7 10.1 0.027 14.1 2.2 1.9 2 0 0 2 2 2 0 TMEM154 protein family Trp_oprn_chp PF09534.5 CDI87029.1 - 0.82 9.2 12.2 0.068 12.7 4.0 1.9 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) YjgP_YjgQ PF03739.9 CDI87029.1 - 1.4 7.6 7.4 4.7 5.8 0.6 2.1 2 0 0 2 2 2 0 Predicted permease YjgP/YjgQ family CBP4 PF07960.6 CDI87029.1 - 1.9 8.0 18.1 1.5 8.4 6.4 2.4 2 0 0 2 2 2 0 CBP4 CD20 PF04103.10 CDI87029.1 - 2.8 7.8 9.3 0.11 12.3 1.9 2.0 2 1 1 3 3 3 0 CD20-like family DUF788 PF05620.6 CDI87029.1 - 4.6 7.0 12.9 0.61 9.9 3.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF788) Corona_nucleoca PF00937.13 CDI87029.1 - 10 4.9 39.5 0.046 12.6 19.2 2.0 1 1 0 2 2 2 0 Coronavirus nucleocapsid protein Nucleoporin_FG PF13634.1 CDI87030.1 - 0.019 15.1 7.8 0.027 14.7 5.4 1.2 1 0 0 1 1 1 0 Nucleoporin FG repeat region Pex14_N PF04695.8 CDI87030.1 - 0.059 13.4 6.7 0.068 13.2 4.7 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF4366 PF14283.1 CDI87030.1 - 0.067 12.6 1.8 0.07 12.5 1.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) DUF4457 PF14652.1 CDI87030.1 - 0.32 9.9 4.9 0.33 9.8 3.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4457) HCO3_cotransp PF00955.16 CDI87030.1 - 0.35 9.4 2.1 0.34 9.5 1.5 1.0 1 0 0 1 1 1 0 HCO3- transporter family Suf PF05843.9 CDI87030.1 - 0.7 9.5 12.1 0.7 9.5 8.4 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) OATP PF03137.15 CDI87030.1 - 1 7.3 5.4 1.1 7.2 3.8 1.0 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family DUF912 PF06024.7 CDI87030.1 - 1 9.4 6.0 2.2 8.4 4.1 1.7 1 1 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF4557 PF15101.1 CDI87030.1 - 4 7.2 19.6 4.4 7.0 13.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) DUF1764 PF08576.5 CDI87030.1 - 6.7 7.5 9.1 7.9 7.3 6.3 1.1 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) Pex26 PF07163.7 CDI87030.1 - 7.8 5.2 10.1 8.6 5.1 7.0 1.0 1 0 0 1 1 1 0 Pex26 protein Serinc PF03348.10 CDI87030.1 - 9.7 4.7 6.8 11 4.5 4.7 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) IER PF05760.7 CDI87031.1 - 0.82 9.5 10.5 0.88 9.4 7.3 1.1 1 0 0 1 1 1 0 Immediate early response protein (IER) Nsp1_C PF05064.8 CDI87031.1 - 1.5 8.5 5.4 15 5.2 1.1 2.2 2 0 0 2 2 2 0 Nsp1-like C-terminal region Med3 PF11593.3 CDI87031.1 - 3.6 6.7 25.6 4.4 6.4 17.8 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal HMA PF00403.21 CDI87032.1 - 1.6e-18 66.5 0.5 3.9e-09 36.5 0.0 2.4 2 0 0 2 2 2 2 Heavy-metal-associated domain DUF2339 PF10101.4 CDI87032.1 - 0.016 13.4 17.5 0.02 13.1 12.2 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2339) Toxin-deaminase PF14424.1 CDI87032.1 - 0.031 14.2 2.7 4 7.4 0.0 2.9 3 1 0 3 3 3 0 The BURPS668_1122 family of deaminases DHHW PF14286.1 CDI87032.1 - 1.3 8.2 4.3 7.3 5.7 0.0 2.1 2 0 0 2 2 2 0 DHHW protein DDHD PF02862.12 CDI87032.1 - 3.2 7.4 5.6 3.3 7.4 1.2 2.0 2 0 0 2 2 2 0 DDHD domain DUF2058 PF09831.4 CDI87032.1 - 3.5 7.4 13.6 2.6 7.8 5.0 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2058) DUF3486 PF11985.3 CDI87032.1 - 5.7 6.9 34.1 4.1 7.4 14.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3486) Paramyxo_C PF01692.13 CDI87032.1 - 8.7 5.8 7.0 5.5 6.5 0.1 2.2 2 0 0 2 2 2 0 Paramyxovirus non-structural protein c RskA PF10099.4 CDI87033.1 - 0.24 11.1 0.0 0.24 11.1 0.0 2.4 2 1 0 2 2 2 0 Anti-sigma-K factor rskA OmpH PF03938.9 CDI87033.1 - 0.46 10.4 36.5 0.67 9.8 25.3 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Ribosomal_60s PF00428.14 CDI87033.1 - 0.51 10.7 5.5 3.2 8.2 3.3 2.0 2 0 0 2 2 2 0 60s Acidic ribosomal protein mono-CXXC PF15626.1 CDI87033.1 - 1.5 8.7 7.0 3.6 7.6 4.9 1.7 1 0 0 1 1 1 0 single CXXC unit SOBP PF15279.1 CDI87033.1 - 2.5 8.3 32.3 3.5 7.9 22.4 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein SR-25 PF10500.4 CDI87033.1 - 6 6.2 42.4 13 5.1 29.4 1.6 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF936 PF06075.7 CDI87034.1 - 0.058 12.3 17.4 0.066 12.1 12.1 1.0 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) CKAP2_C PF15297.1 CDI87034.1 - 0.21 10.3 18.5 0.27 10.0 12.8 1.1 1 0 0 1 1 1 0 Cytoskeleton-associated protein 2 C-terminus BLVR PF06375.6 CDI87034.1 - 0.37 10.6 14.5 0.49 10.2 10.1 1.1 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) DUF1645 PF07816.6 CDI87034.1 - 0.46 10.9 13.7 1 9.7 9.5 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1645) DivIC PF04977.10 CDI87034.1 - 0.48 9.9 33.3 1.7 8.1 8.1 2.2 2 0 0 2 2 2 0 Septum formation initiator DUF572 PF04502.8 CDI87034.1 - 0.59 9.3 18.7 0.68 9.0 13.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) AF-4 PF05110.8 CDI87034.1 - 0.86 7.3 20.5 1.2 6.9 14.2 1.2 1 0 0 1 1 1 0 AF-4 proto-oncoprotein PH_5 PF15405.1 CDI87034.1 - 1.5 8.7 14.2 0.34 10.8 6.6 1.9 1 1 1 2 2 2 0 Pleckstrin homology domain RE_AlwI PF09491.5 CDI87034.1 - 1.6 7.1 10.0 1.9 6.8 6.9 1.0 1 0 0 1 1 1 0 AlwI restriction endonuclease WBS_methylT PF12589.3 CDI87034.1 - 2.3 8.7 20.2 0.94 10.0 6.7 2.1 2 0 0 2 2 2 0 Methyltransferase involved in Williams-Beuren syndrome eIF-3_zeta PF05091.7 CDI87034.1 - 2.4 6.6 21.3 2.9 6.4 14.8 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF2681 PF10883.3 CDI87034.1 - 2.8 8.1 32.5 0.25 11.5 8.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) SAPS PF04499.10 CDI87034.1 - 3.2 6.2 18.0 3.8 6.0 12.5 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF1675 PF07897.6 CDI87034.1 - 3.2 7.5 13.3 4.3 7.1 9.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) DUF3405 PF11885.3 CDI87034.1 - 3.5 5.7 14.5 4.1 5.5 10.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3405) CENP-T PF15511.1 CDI87034.1 - 3.6 6.7 20.8 4.3 6.4 14.4 1.0 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T LUC7 PF03194.10 CDI87034.1 - 3.6 7.0 16.2 4.8 6.6 11.2 1.1 1 0 0 1 1 1 0 LUC7 N_terminus Neur_chan_memb PF02932.11 CDI87034.1 - 4.2 7.1 15.5 5.1 6.9 10.8 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF2146 PF10220.4 CDI87034.1 - 4.8 5.0 17.7 5.4 4.8 12.3 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2146) DUF4045 PF13254.1 CDI87034.1 - 5.4 6.1 19.0 6.5 5.9 13.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) MMR1 PF08505.5 CDI87034.1 - 5.8 6.8 24.2 8.7 6.2 16.8 1.2 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein CDC45 PF02724.9 CDI87034.1 - 6.4 4.6 21.2 7.9 4.3 14.7 1.1 1 0 0 1 1 1 0 CDC45-like protein COX6A PF02046.10 CDI87034.1 - 6.4 6.7 11.6 3 7.8 2.2 2.1 2 0 0 2 2 2 0 Cytochrome c oxidase subunit VIa PBP1_TM PF14812.1 CDI87034.1 - 6.4 7.1 11.9 7.7 6.9 3.2 2.1 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Hid1 PF12722.2 CDI87034.1 - 6.6 4.2 22.1 7.8 4.0 15.3 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF2149 PF09919.4 CDI87034.1 - 6.7 6.8 12.4 1.1 9.4 2.1 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2149) PLRV_ORF5 PF01690.12 CDI87034.1 - 6.9 5.6 21.1 7.5 5.5 14.6 1.0 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein GAGA_bind PF06217.7 CDI87034.1 - 6.9 6.5 20.1 8 6.3 13.9 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family Herpes_DNAp_acc PF04929.7 CDI87034.1 - 7.2 5.4 19.6 8.8 5.1 13.6 1.0 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Dehalogenase PF13486.1 CDI87034.1 - 8.1 5.7 15.6 0.053 12.9 3.5 1.9 1 1 1 2 2 2 0 Reductive dehalogenase subunit DUF2956 PF11169.3 CDI87034.1 - 8.2 6.4 29.9 2.1 8.3 9.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2956) GPCR_chapero_1 PF11904.3 CDI87034.1 - 9.9 5.1 16.8 14 4.6 11.6 1.2 1 0 0 1 1 1 0 GPCR-chaperone Bud13 PF09736.4 CDI87034.1 - 10 6.4 24.6 10 6.3 8.6 2.0 2 0 0 2 2 2 0 Pre-mRNA-splicing factor of RES complex Peptidase_M28 PF04389.12 CDI87035.1 - 0.004 16.9 0.0 0.0063 16.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 SR-25 PF10500.4 CDI87036.1 - 0.0002 20.8 19.5 0.0002 20.8 13.5 6.4 3 2 2 5 5 5 1 Nuclear RNA-splicing-associated protein Exonuc_VII_L PF02601.10 CDI87037.1 - 0.12 11.6 21.1 0.14 11.3 14.6 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit TFIIA PF03153.8 CDI87037.1 - 1.1 9.0 25.6 1.3 8.8 17.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF342 PF03961.8 CDI87037.1 - 1.8 6.8 12.7 2.5 6.4 8.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Spc7 PF08317.6 CDI87037.1 - 1.9 7.0 22.7 2.6 6.6 15.7 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Reo_sigmaC PF04582.7 CDI87037.1 - 1.9 7.5 7.4 4.5 6.3 5.1 1.6 1 1 0 1 1 1 0 Reovirus sigma C capsid protein COG5 PF10392.4 CDI87037.1 - 2.4 8.1 19.9 3.2 7.7 12.6 1.8 1 1 1 2 2 2 0 Golgi transport complex subunit 5 V_ATPase_I PF01496.14 CDI87037.1 - 2.7 5.7 15.0 3.9 5.2 10.4 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family HlyD_2 PF12700.2 CDI87037.1 - 5.1 6.1 15.9 6.3 5.8 11.0 1.3 1 0 0 1 1 1 0 HlyD family secretion protein APG6 PF04111.7 CDI87037.1 - 5.2 6.0 25.0 7.8 5.4 17.3 1.4 1 0 0 1 1 1 0 Autophagy protein Apg6 ATG16 PF08614.6 CDI87037.1 - 5.8 6.6 38.8 6.7 6.4 13.7 2.1 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) LMBR1 PF04791.11 CDI87037.1 - 5.8 5.3 13.0 7.9 4.9 9.0 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein POP1 PF06978.6 CDI87038.1 - 0.056 13.0 10.2 0.061 12.9 7.1 1.0 1 0 0 1 1 1 0 Ribonucleases P/MRP protein subunit POP1 DUF702 PF05142.7 CDI87038.1 - 0.15 12.1 13.8 0.17 12.0 9.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF702) NARP1 PF12569.3 CDI87038.1 - 0.23 10.1 14.7 0.23 10.1 10.2 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DUF3984 PF13136.1 CDI87038.1 - 0.25 10.5 12.8 0.28 10.3 8.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3984) Tfb4 PF03850.9 CDI87038.1 - 0.36 10.0 7.4 0.38 9.9 5.1 1.0 1 0 0 1 1 1 0 Transcription factor Tfb4 CDC73 PF05179.9 CDI87038.1 - 0.59 9.4 12.9 0.62 9.3 8.9 1.0 1 0 0 1 1 1 0 RNA pol II accessory factor, Cdc73 family Peptidase_S64 PF08192.6 CDI87038.1 - 0.64 8.2 12.2 0.63 8.3 8.4 1.0 1 0 0 1 1 1 0 Peptidase family S64 ARF7EP_C PF14949.1 CDI87038.1 - 0.66 10.4 12.1 0.89 10.0 8.4 1.4 1 0 0 1 1 1 0 ARF7 effector protein C-terminus ig PF00047.20 CDI87038.1 - 0.76 9.9 6.3 1.8 8.7 4.4 1.8 1 1 0 1 1 1 0 Immunoglobulin domain FemAB PF02388.11 CDI87038.1 - 0.88 8.1 16.9 0.96 8.0 11.7 1.0 1 0 0 1 1 1 0 FemAB family VID27 PF08553.5 CDI87038.1 - 1.3 7.1 10.5 1.3 7.1 7.3 1.0 1 0 0 1 1 1 0 VID27 cytoplasmic protein DUF3464 PF11947.3 CDI87038.1 - 1.3 8.4 13.6 1.6 8.1 9.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) DUF2370 PF10176.4 CDI87038.1 - 1.4 8.2 8.1 1.3 8.2 5.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) RNA_pol_Rpc4 PF05132.9 CDI87038.1 - 1.4 8.9 15.2 2 8.3 10.5 1.4 1 0 0 1 1 1 0 RNA polymerase III RPC4 FAM60A PF15396.1 CDI87038.1 - 1.4 8.6 12.2 1.7 8.3 8.5 1.1 1 0 0 1 1 1 0 Protein Family FAM60A PRP3 PF08572.5 CDI87038.1 - 1.5 8.1 21.3 1.7 7.9 14.7 1.0 1 0 0 1 1 1 0 pre-mRNA processing factor 3 (PRP3) eIF-3_zeta PF05091.7 CDI87038.1 - 1.6 7.2 21.3 1.5 7.3 14.8 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) CKAP2_C PF15297.1 CDI87038.1 - 1.6 7.4 17.7 1.8 7.3 12.3 1.0 1 0 0 1 1 1 0 Cytoskeleton-associated protein 2 C-terminus YqfQ PF14181.1 CDI87038.1 - 1.9 8.5 22.8 2.2 8.2 15.8 1.0 1 0 0 1 1 1 0 YqfQ-like protein DUF913 PF06025.7 CDI87038.1 - 2 7.0 10.1 2 7.0 7.0 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DUF853 PF05872.7 CDI87038.1 - 2.4 6.3 15.1 2.9 6.1 10.5 1.0 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) DUF1764 PF08576.5 CDI87038.1 - 2.5 8.9 19.2 4.1 8.2 13.3 1.4 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) AAA_11 PF13086.1 CDI87038.1 - 2.7 7.5 15.0 3.1 7.3 10.4 1.0 1 0 0 1 1 1 0 AAA domain DUF4175 PF13779.1 CDI87038.1 - 2.7 5.6 48.2 3 5.4 33.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) DUF1510 PF07423.6 CDI87038.1 - 2.8 7.2 21.8 3.2 7.0 15.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) TRAP_alpha PF03896.11 CDI87038.1 - 2.9 6.8 7.7 3.2 6.6 5.3 1.0 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Tim54 PF11711.3 CDI87038.1 - 2.9 6.3 14.7 3 6.3 10.2 1.0 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Raftlin PF15250.1 CDI87038.1 - 3 6.2 16.2 3.2 6.1 11.2 1.0 1 0 0 1 1 1 0 Raftlin Strabismus PF06638.6 CDI87038.1 - 3.1 6.0 9.3 3.5 5.8 6.4 1.0 1 0 0 1 1 1 0 Strabismus protein Spc7_N PF15402.1 CDI87038.1 - 3.3 5.5 22.8 3.7 5.4 15.8 1.0 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 RIC3 PF15361.1 CDI87038.1 - 3.3 7.9 19.3 3.7 7.7 13.4 1.1 1 0 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 DUF4045 PF13254.1 CDI87038.1 - 3.4 6.8 16.7 3.6 6.7 11.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) SAGA-Tad1 PF12767.2 CDI87038.1 - 3.8 7.1 21.3 4 7.0 14.8 1.1 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit DDRGK PF09756.4 CDI87038.1 - 3.8 6.8 27.2 4.3 6.6 18.8 1.0 1 0 0 1 1 1 0 DDRGK domain Band_3_cyto PF07565.8 CDI87038.1 - 3.8 6.9 17.9 4.6 6.6 12.4 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Gti1_Pac2 PF09729.4 CDI87038.1 - 4.4 7.1 14.0 5.2 6.9 9.7 1.1 1 0 0 1 1 1 0 Gti1/Pac2 family LIM_bind PF01803.11 CDI87038.1 - 4.6 6.2 19.1 6.7 5.7 13.3 1.3 1 0 0 1 1 1 0 LIM-domain binding protein Dynamin_N PF00350.18 CDI87038.1 - 4.8 6.9 10.2 5.7 6.7 7.1 1.2 1 0 0 1 1 1 0 Dynamin family Pal1 PF08316.6 CDI87038.1 - 4.8 7.6 10.2 5.4 7.4 7.1 1.1 1 0 0 1 1 1 0 Pal1 cell morphology protein BORG_CEP PF14957.1 CDI87038.1 - 4.8 8.1 15.6 5.7 7.8 10.8 1.1 1 0 0 1 1 1 0 Cdc42 effector GOLD_2 PF13897.1 CDI87038.1 - 5.1 7.3 7.2 6.7 6.9 5.0 1.3 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking ARD PF03079.9 CDI87038.1 - 5.2 6.9 9.3 6 6.7 6.4 1.1 1 0 0 1 1 1 0 ARD/ARD' family FAM91_C PF14648.1 CDI87038.1 - 5.3 5.7 9.8 5.5 5.7 6.8 1.0 1 0 0 1 1 1 0 FAM91 C-terminus SpoIIP PF07454.6 CDI87038.1 - 5.4 6.0 14.3 5.9 5.9 9.9 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) DUF4355 PF14265.1 CDI87038.1 - 5.5 6.9 26.3 6.7 6.6 18.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4355) Neur_chan_memb PF02932.11 CDI87038.1 - 5.5 6.7 14.6 6.5 6.5 10.1 1.0 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region CDC45 PF02724.9 CDI87038.1 - 5.6 4.8 17.7 6.1 4.7 12.2 1.0 1 0 0 1 1 1 0 CDC45-like protein Pox_Ag35 PF03286.9 CDI87038.1 - 5.7 6.4 14.3 6.6 6.2 9.9 1.0 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Afi1 PF07792.7 CDI87038.1 - 5.8 6.9 16.5 7 6.6 11.4 1.1 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking AUX_IAA PF02309.11 CDI87038.1 - 5.9 6.5 15.0 6.7 6.3 10.4 1.1 1 0 0 1 1 1 0 AUX/IAA family DUF4407 PF14362.1 CDI87038.1 - 6 5.7 21.3 6.2 5.6 14.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Rtf2 PF04641.7 CDI87038.1 - 6.7 5.8 19.3 8.1 5.5 13.3 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger SAPS PF04499.10 CDI87038.1 - 6.8 5.2 17.0 7.6 5.0 11.8 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein BTV_NS2 PF04514.7 CDI87038.1 - 6.9 5.4 14.9 7.4 5.3 10.3 1.0 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Dehalogenase PF13486.1 CDI87038.1 - 7 5.9 10.3 7.7 5.8 7.1 1.0 1 0 0 1 1 1 0 Reductive dehalogenase subunit Spore_coat_CotO PF14153.1 CDI87038.1 - 7.6 5.9 28.1 8.6 5.7 19.5 1.0 1 0 0 1 1 1 0 Spore coat protein CotO DUF1917 PF08939.5 CDI87038.1 - 7.8 6.1 13.2 8.3 6.0 9.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1917) F-protein PF00469.15 CDI87038.1 - 8 5.7 15.9 9.1 5.5 11.0 1.0 1 0 0 1 1 1 0 Negative factor, (F-Protein) or Nef Paf1 PF03985.8 CDI87038.1 - 8 5.0 26.7 9 4.9 18.5 1.0 1 0 0 1 1 1 0 Paf1 DUF2828 PF11443.3 CDI87038.1 - 8.1 4.5 13.4 9 4.3 9.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) SUFU_C PF12470.3 CDI87038.1 - 8.2 5.9 9.5 8.9 5.8 6.6 1.0 1 0 0 1 1 1 0 Suppressor of Fused Gli/Ci N terminal binding domain PIH1 PF08190.7 CDI87038.1 - 8.3 5.7 25.0 9.5 5.5 17.3 1.0 1 0 0 1 1 1 0 pre-RNA processing PIH1/Nop17 G-7-MTase PF12803.2 CDI87038.1 - 8.3 5.4 9.5 9.2 5.2 6.6 1.1 1 0 0 1 1 1 0 mRNA (guanine-7-)methyltransferase (G-7-MTase) DUF3513 PF12026.3 CDI87038.1 - 8.4 5.8 21.9 9.9 5.6 15.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3513) Sox_N PF12444.3 CDI87038.1 - 8.5 7.5 13.0 11 7.2 9.0 1.2 1 0 0 1 1 1 0 Sox developmental protein N terminal OATP PF03137.15 CDI87038.1 - 8.5 4.2 12.7 8.8 4.2 8.8 1.2 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Asp-B-Hydro_N PF05279.6 CDI87038.1 - 8.7 6.1 16.0 9.8 5.9 11.1 1.0 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Mem_trans PF03547.13 CDI87038.1 - 8.7 4.5 12.0 10 4.2 8.3 1.0 1 0 0 1 1 1 0 Membrane transport protein DUF966 PF06136.8 CDI87038.1 - 8.9 5.6 17.0 10 5.4 11.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Bud13 PF09736.4 CDI87038.1 - 9.3 6.5 25.2 12 6.1 17.5 1.1 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex RR_TM4-6 PF06459.7 CDI87038.1 - 9.7 5.9 22.0 11 5.8 15.2 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF2413 PF10310.4 CDI87038.1 - 9.8 4.8 24.2 12 4.6 16.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) LCD1 PF09798.4 CDI87039.1 - 0.16 9.9 3.8 0.15 10.0 2.6 1.1 1 0 0 1 1 1 0 DNA damage checkpoint protein Draxin PF15550.1 CDI87039.1 - 0.71 9.4 4.6 0.81 9.2 3.2 1.1 1 0 0 1 1 1 0 Draxin DUF572 PF04502.8 CDI87039.1 - 0.73 8.9 7.1 0.84 8.7 4.9 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) ASFV_J13L PF05568.6 CDI87039.1 - 0.78 9.2 15.9 0.96 8.9 11.0 1.1 1 0 0 1 1 1 0 African swine fever virus J13L protein AUX_IAA PF02309.11 CDI87039.1 - 1.5 8.5 7.9 2 8.1 5.5 1.2 1 0 0 1 1 1 0 AUX/IAA family Macoilin PF09726.4 CDI87039.1 - 1.7 6.8 10.8 1.9 6.6 7.5 1.0 1 0 0 1 1 1 0 Transmembrane protein Mcm10 PF09332.6 CDI87039.1 - 2 7.6 11.7 2.4 7.4 8.1 1.1 1 0 0 1 1 1 0 Mcm10 replication factor FimP PF09766.4 CDI87039.1 - 2.3 7.2 13.6 3.1 6.7 9.4 1.1 1 0 0 1 1 1 0 Fms-interacting protein MCPVI PF02993.9 CDI87039.1 - 2.5 8.2 12.1 3 7.9 8.4 1.0 1 0 0 1 1 1 0 Minor capsid protein VI IER PF05760.7 CDI87039.1 - 2.9 7.7 15.6 3.4 7.4 10.8 1.1 1 0 0 1 1 1 0 Immediate early response protein (IER) Peptidase_S64 PF08192.6 CDI87039.1 - 2.9 6.1 9.8 3.1 6.0 6.8 1.0 1 0 0 1 1 1 0 Peptidase family S64 Hid1 PF12722.2 CDI87039.1 - 4.1 4.9 9.6 4.5 4.8 6.6 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Paramyxo_ncap PF00973.14 CDI87039.1 - 5.8 5.4 7.8 6.1 5.4 5.4 1.0 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein PAT1 PF09770.4 CDI87039.1 - 6.3 4.9 23.6 7.1 4.7 16.4 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 PIH1 PF08190.7 CDI87039.1 - 7.6 5.8 14.1 9.5 5.5 9.8 1.2 1 0 0 1 1 1 0 pre-RNA processing PIH1/Nop17 RED_N PF07808.8 CDI87039.1 - 7.8 5.6 10.9 11 5.1 7.5 1.3 1 0 0 1 1 1 0 RED-like protein N-terminal region Pol_alpha_B_N PF08418.5 CDI87039.1 - 9.3 5.6 12.8 12 5.3 8.9 1.2 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal DUF2453 PF10507.4 CDI87040.1 - 0.022 14.5 0.0 0.033 14.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2453) FimP PF09766.4 CDI87042.1 - 0.0018 17.3 17.6 0.0018 17.3 12.2 3.5 3 1 0 3 3 3 1 Fms-interacting protein Pribosyltran PF00156.22 CDI87042.1 - 0.95 9.1 2.8 3.8 7.2 1.9 2.2 1 1 0 1 1 1 0 Phosphoribosyl transferase domain GTP_EFTU PF00009.22 CDI87043.1 - 1e-15 57.6 0.0 6.8e-07 28.9 0.0 2.7 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain EFG_II PF14492.1 CDI87043.1 - 9.8e-11 41.3 0.0 2e-10 40.3 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II BAF1_ABF1 PF04684.8 CDI87043.1 - 0.0016 17.3 5.7 0.0016 17.3 4.0 9.0 7 2 0 9 9 9 2 BAF1 / ABF1 chromatin reorganising factor GTP_EFTU_D2 PF03144.20 CDI87043.1 - 0.0083 16.2 0.0 0.031 14.3 0.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 2 TrbC_Ftype PF09673.5 CDI87043.1 - 0.013 15.1 0.0 0.06 12.9 0.0 2.2 1 0 0 1 1 1 0 Type-F conjugative transfer system pilin assembly protein YjgP_YjgQ PF03739.9 CDI87043.1 - 0.072 11.8 7.3 0.6 8.7 0.6 2.5 2 0 0 2 2 2 0 Predicted permease YjgP/YjgQ family Neur_chan_memb PF02932.11 CDI87043.1 - 2.1 8.2 6.5 7 6.4 0.7 3.1 3 0 0 3 3 3 0 Neurotransmitter-gated ion-channel transmembrane region KH_1 PF00013.24 CDI87046.1 - 1.1e-35 121.0 0.0 5.1e-09 35.6 0.1 4.8 5 0 0 5 5 5 4 KH domain KH_3 PF13014.1 CDI87046.1 - 1.4e-29 101.2 0.7 2.7e-07 30.0 0.2 4.9 4 0 0 4 4 4 4 KH domain KH_2 PF07650.12 CDI87046.1 - 0.0017 17.8 0.0 1.3 8.6 0.0 3.3 3 0 0 3 3 3 1 KH domain Mem_trans PF03547.13 CDI87046.1 - 0.0032 15.8 0.1 0.0032 15.8 0.1 2.2 1 1 1 2 2 2 1 Membrane transport protein Pkinase PF00069.20 CDI87047.1 - 3e-22 79.0 0.0 6.2e-22 77.9 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.1 CDI87047.1 - 6.4e-21 74.5 0.0 9.9e-21 73.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_Tyr PF07714.12 CDI87047.1 - 4.9e-05 22.5 0.0 0.00011 21.4 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 CDI87047.1 - 0.0058 15.7 0.0 0.0098 14.9 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family MFS_1 PF07690.11 CDI87048.1 - 2.8e-12 46.0 40.1 8.9e-08 31.2 19.7 3.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Beta-lactamase PF00144.19 CDI87049.1 - 8.8e-43 146.5 0.3 1.3e-37 129.6 0.0 3.2 2 1 0 2 2 2 2 Beta-lactamase ABC1 PF03109.11 CDI87049.1 - 6e-24 84.3 0.0 1.2e-23 83.3 0.0 1.5 1 0 0 1 1 1 1 ABC1 family WaaY PF06176.6 CDI87049.1 - 0.001 18.3 0.0 0.0017 17.6 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide core biosynthesis protein (WaaY) RIO1 PF01163.17 CDI87049.1 - 0.0049 16.2 0.1 0.015 14.6 0.0 1.7 2 0 0 2 2 2 1 RIO1 family RabGAP-TBC PF00566.13 CDI87050.1 - 1e-30 106.8 6.2 2.8e-30 105.3 0.2 2.7 3 0 0 3 3 3 2 Rab-GTPase-TBC domain Kinase-like PF14531.1 CDI87051.1 - 5e-18 65.0 0.0 7.8e-18 64.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like BEX PF04538.7 CDI87051.1 - 1.2 9.3 5.7 2.1 8.5 3.9 1.3 1 0 0 1 1 1 0 Brain expressed X-linked like family SOBP PF15279.1 CDI87051.1 - 4.3 7.6 11.0 9.5 6.4 7.7 1.5 1 0 0 1 1 1 0 Sine oculis-binding protein Mito_carr PF00153.22 CDI87052.1 - 4.7e-32 109.5 15.3 5.1e-12 45.3 0.0 4.9 4 1 0 4 4 4 3 Mitochondrial carrier protein DUF849 PF05853.7 CDI87052.1 - 0.0095 14.8 0.1 0.016 14.0 0.1 1.3 1 0 0 1 1 1 1 Prokaryotic protein of unknown function (DUF849) Adap_comp_sub PF00928.16 CDI87053.1 - 9.5e-82 274.0 0.0 1.1e-81 273.7 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 CDI87053.1 - 3.2e-05 23.6 0.1 5.9e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Rep_fac_C PF08542.6 CDI87053.1 - 0.076 12.9 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 Replication factor C C-terminal domain Atrophin-1 PF03154.10 CDI87056.1 - 0.023 12.8 0.5 0.026 12.6 0.3 1.1 1 0 0 1 1 1 0 Atrophin-1 family Rxt3 PF08642.5 CDI87057.1 - 0.0049 17.0 1.0 0.006 16.8 0.7 1.0 1 0 0 1 1 1 1 Histone deacetylation protein Rxt3 PFL PF02901.10 CDI87057.1 - 0.0065 14.9 1.2 0.0068 14.8 0.8 1.1 1 0 0 1 1 1 1 Pyruvate formate lyase NPR3 PF03666.8 CDI87057.1 - 0.012 14.2 3.0 0.013 14.0 2.1 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 FAM176 PF14851.1 CDI87057.1 - 0.019 14.6 2.7 0.018 14.7 1.9 1.1 1 0 0 1 1 1 0 FAM176 family DUF913 PF06025.7 CDI87057.1 - 0.031 13.0 1.3 0.034 12.9 0.9 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DUF912 PF06024.7 CDI87057.1 - 0.041 13.9 1.9 0.049 13.6 1.3 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Tom22 PF04281.8 CDI87057.1 - 0.049 13.1 1.4 0.05 13.1 1.0 1.1 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 DUF3306 PF11748.3 CDI87057.1 - 0.062 13.9 3.7 0.057 14.0 2.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3306) EIIBC-GUT_N PF03612.9 CDI87057.1 - 0.15 11.6 4.2 0.18 11.4 2.9 1.0 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus MotA_ExbB PF01618.11 CDI87057.1 - 0.18 11.4 0.4 0.21 11.1 0.3 1.1 1 0 0 1 1 1 0 MotA/TolQ/ExbB proton channel family DUF2201_N PF13203.1 CDI87057.1 - 0.18 10.9 6.2 0.18 10.9 4.3 1.0 1 0 0 1 1 1 0 Putative metallopeptidase domain Tim54 PF11711.3 CDI87057.1 - 0.23 9.9 2.9 0.25 9.8 2.0 1.0 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Suf PF05843.9 CDI87057.1 - 0.26 10.9 8.5 0.26 10.9 5.9 1.0 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) PEX11 PF05648.9 CDI87057.1 - 0.28 10.4 1.5 0.29 10.3 1.0 1.0 1 0 0 1 1 1 0 Peroxisomal biogenesis factor 11 (PEX11) Kei1 PF08552.6 CDI87057.1 - 0.36 10.4 1.5 0.39 10.3 1.0 1.0 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 DUF775 PF05603.7 CDI87057.1 - 0.44 10.0 5.7 0.47 9.9 4.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF775) DUF4557 PF15101.1 CDI87057.1 - 0.49 10.1 11.5 0.52 10.1 7.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) DUF4366 PF14283.1 CDI87057.1 - 0.49 9.7 4.8 0.56 9.5 3.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) AUX_IAA PF02309.11 CDI87057.1 - 0.52 10.0 3.5 0.54 9.9 2.4 1.0 1 0 0 1 1 1 0 AUX/IAA family Spore_coat_CotO PF14153.1 CDI87057.1 - 0.54 9.6 13.1 0.62 9.4 9.1 1.0 1 0 0 1 1 1 0 Spore coat protein CotO DnaJ-X PF14308.1 CDI87057.1 - 0.59 9.3 7.7 0.67 9.1 5.3 1.0 1 0 0 1 1 1 0 X-domain of DnaJ-containing DUF3464 PF11947.3 CDI87057.1 - 0.6 9.5 3.0 0.63 9.4 2.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) RIC3 PF15361.1 CDI87057.1 - 0.6 10.3 5.6 0.59 10.3 3.9 1.1 1 0 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 HNOBA PF07701.9 CDI87057.1 - 0.64 9.1 5.1 0.7 9.0 3.5 1.0 1 0 0 1 1 1 0 Heme NO binding associated Peptidase_S49_N PF08496.5 CDI87057.1 - 0.69 9.6 5.2 0.75 9.5 3.6 1.0 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Zip PF02535.17 CDI87057.1 - 0.71 8.8 4.4 0.77 8.7 3.0 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter PAT1 PF09770.4 CDI87057.1 - 0.74 7.9 16.4 0.67 8.1 11.4 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Glyco_transf_15 PF01793.11 CDI87057.1 - 0.94 8.3 4.9 1 8.2 3.4 1.0 1 0 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase Pex14_N PF04695.8 CDI87057.1 - 1.1 9.2 7.4 1.2 9.1 5.2 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF2946 PF11162.3 CDI87057.1 - 1.2 9.3 5.1 1.5 9.0 3.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2946) FHIPEP PF00771.15 CDI87057.1 - 1.3 7.2 4.7 1.4 7.1 3.3 1.0 1 0 0 1 1 1 0 FHIPEP family TMEM51 PF15345.1 CDI87057.1 - 1.5 8.4 9.2 1.6 8.4 6.3 1.1 1 0 0 1 1 1 0 Transmembrane protein 51 PH_4 PF15404.1 CDI87057.1 - 1.5 8.2 6.6 1.8 8.0 4.6 1.0 1 0 0 1 1 1 0 Pleckstrin homology domain Pex16 PF08610.5 CDI87057.1 - 2.2 7.1 5.6 2.1 7.2 3.9 1.0 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) Med15 PF09606.5 CDI87057.1 - 2.8 6.0 25.2 2.7 6.0 17.5 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal IncA PF04156.9 CDI87057.1 - 2.9 7.4 13.5 3.3 7.2 9.4 1.1 1 0 0 1 1 1 0 IncA protein ATAD4 PF15321.1 CDI87057.1 - 3.5 8.6 7.6 4.3 8.4 5.3 1.1 1 0 0 1 1 1 0 ATPase family AAA domain containing 4 RED_N PF07808.8 CDI87057.1 - 3.9 6.6 14.0 4.4 6.4 9.7 1.0 1 0 0 1 1 1 0 RED-like protein N-terminal region RR_TM4-6 PF06459.7 CDI87057.1 - 4.1 7.2 8.9 4.5 7.0 6.2 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 PBP1_TM PF14812.1 CDI87057.1 - 4.1 7.7 6.5 5 7.5 4.5 1.1 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Folate_carrier PF01770.13 CDI87057.1 - 4.4 5.6 5.3 4.7 5.6 3.6 1.0 1 0 0 1 1 1 0 Reduced folate carrier Serinc PF03348.10 CDI87057.1 - 4.9 5.7 7.2 5.4 5.6 5.0 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) Band_3_cyto PF07565.8 CDI87057.1 - 5.2 6.5 8.9 6 6.3 6.2 1.0 1 0 0 1 1 1 0 Band 3 cytoplasmic domain DUF4199 PF13858.1 CDI87057.1 - 5.3 6.9 5.3 6 6.7 3.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) DUF1840 PF08895.6 CDI87057.1 - 5.3 7.1 8.2 6.9 6.7 5.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1840) SseC PF04888.7 CDI87057.1 - 5.7 6.1 15.8 6.5 5.9 11.0 1.0 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family CD20 PF04103.10 CDI87057.1 - 7.5 6.4 5.9 9 6.2 4.1 1.1 1 0 0 1 1 1 0 CD20-like family AIF_C PF14721.1 CDI87057.1 - 8.1 6.6 7.6 9.7 6.4 5.2 1.1 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Conotoxin PF02950.12 CDI87057.1 - 8.5 7.2 9.5 11 6.9 6.6 1.1 1 0 0 1 1 1 0 Conotoxin ACBP PF00887.14 CDI87058.1 - 5e-05 22.8 5.6 0.00023 20.7 2.5 2.6 1 1 1 2 2 2 2 Acyl CoA binding protein PAT1 PF09770.4 CDI87058.1 - 0.0013 17.0 89.0 0.0088 14.3 18.1 2.1 2 0 0 2 2 2 2 Topoisomerase II-associated protein PAT1 Sporozoite_P67 PF05642.6 CDI87058.1 - 0.019 12.8 0.1 0.019 12.8 0.0 2.1 1 1 1 2 2 2 0 Sporozoite P67 surface antigen SAGA-Tad1 PF12767.2 CDI87058.1 - 4.9 6.7 42.6 5.7 6.5 10.7 2.3 2 0 0 2 2 2 0 Transcriptional regulator of RNA polII, SAGA, subunit Plasmodium_Vir PF05795.6 CDI87058.1 - 6.3 5.8 14.2 5.1 6.1 0.8 2.2 2 0 0 2 2 2 0 Plasmodium vivax Vir protein DUF4045 PF13254.1 CDI87058.1 - 8 5.6 35.0 1 8.5 7.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4045) TFIIA PF03153.8 CDI87058.1 - 9.3 6.0 66.7 2.5 7.8 18.0 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit PEX-1N PF09262.6 CDI87059.1 - 3.7e-09 36.4 0.0 8.8e-09 35.3 0.0 1.6 1 0 0 1 1 1 1 Peroxisome biogenesis factor 1, N-terminal DUF2722 PF10846.3 CDI87059.1 - 0.00026 20.1 21.2 0.18 10.7 0.6 3.5 3 0 0 3 3 3 3 Protein of unknown function (DUF2722) Suf PF05843.9 CDI87059.1 - 0.0074 16.0 30.5 0.093 12.4 1.2 3.3 3 0 0 3 3 3 3 Suppressor of forked protein (Suf) Med15 PF09606.5 CDI87059.1 - 0.043 12.0 76.8 0.0034 15.6 8.2 3.4 3 0 0 3 3 3 0 ARC105 or Med15 subunit of Mediator complex non-fungal Spt20 PF12090.3 CDI87059.1 - 0.07 12.4 27.0 0.6 9.4 1.0 3.3 3 0 0 3 3 3 0 Spt20 family TFIIA PF03153.8 CDI87059.1 - 0.23 11.3 41.8 0.2 11.5 3.9 3.4 3 0 0 3 3 3 0 Transcription factor IIA, alpha/beta subunit Neur_chan_memb PF02932.11 CDI87059.1 - 2 8.2 8.8 0.73 9.6 0.7 2.8 3 0 0 3 3 3 0 Neurotransmitter-gated ion-channel transmembrane region BRF1 PF07741.8 CDI87059.1 - 3 8.1 23.7 0.51 10.5 0.4 4.2 4 0 0 4 4 4 0 Brf1-like TBP-binding domain Rsc14 PF08586.5 CDI87059.1 - 3.4 8.2 16.3 6.1 7.3 1.2 3.7 3 0 0 3 3 3 0 RSC complex, Rsc14/Ldb7 subunit PAT1 PF09770.4 CDI87059.1 - 9.5 4.3 53.7 0.38 8.9 4.8 3.2 3 0 0 3 3 3 0 Topoisomerase II-associated protein PAT1 ABC_membrane PF00664.18 CDI87060.1 - 7.1e-68 228.9 22.4 3.6e-42 144.6 6.3 3.3 3 0 0 3 3 3 3 ABC transporter transmembrane region ABC_tran PF00005.22 CDI87060.1 - 1.6e-48 164.4 0.0 1e-28 100.3 0.0 3.3 2 1 0 2 2 2 2 ABC transporter SMC_N PF02463.14 CDI87060.1 - 5.3e-14 51.9 1.6 9.8e-07 28.2 0.6 3.1 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 CDI87060.1 - 1.4e-08 35.0 0.0 0.005 16.8 0.0 3.2 2 1 0 2 2 2 2 AAA domain ABC_ATPase PF09818.4 CDI87060.1 - 3.1e-07 29.3 0.6 0.017 13.7 0.0 2.7 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_16 PF13191.1 CDI87060.1 - 4.1e-07 30.1 0.1 1.5e-05 25.0 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain SbcCD_C PF13558.1 CDI87060.1 - 9e-06 25.5 3.3 0.073 12.9 0.1 4.1 3 2 0 3 3 3 2 Putative exonuclease SbcCD, C subunit AAA_22 PF13401.1 CDI87060.1 - 9.4e-06 25.8 0.5 0.19 11.8 0.0 3.4 3 0 0 3 3 3 1 AAA domain AAA_25 PF13481.1 CDI87060.1 - 0.00061 19.2 0.1 1.4 8.2 0.0 3.3 3 0 0 3 3 3 1 AAA domain DUF258 PF03193.11 CDI87060.1 - 0.00063 18.9 0.0 0.0012 18.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 CDI87060.1 - 0.0042 16.5 0.1 0.0096 15.4 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain Cas_NE0113 PF09623.5 CDI87060.1 - 0.0075 15.7 0.7 0.045 13.2 0.0 2.2 2 0 0 2 2 2 1 CRISPR-associated protein NE0113 (Cas_NE0113) AAA_17 PF13207.1 CDI87060.1 - 0.0076 17.0 0.0 0.019 15.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 CDI87060.1 - 0.014 15.6 3.6 4.8 7.3 0.0 3.4 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 CDI87060.1 - 0.021 15.1 0.3 0.29 11.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.17 CDI87060.1 - 0.029 13.2 0.1 0.15 10.8 0.0 2.0 2 0 0 2 2 2 0 NB-ARC domain AAA_5 PF07728.9 CDI87060.1 - 0.033 13.9 0.0 0.098 12.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.12 CDI87060.1 - 0.12 11.8 2.0 9.9 5.5 0.0 2.8 3 0 0 3 3 3 0 IstB-like ATP binding protein OmpH PF03938.9 CDI87062.1 - 0.061 13.2 22.3 0.059 13.2 15.4 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) SprA-related PF12118.3 CDI87062.1 - 0.081 12.2 57.5 0.1 11.9 39.9 1.0 1 0 0 1 1 1 0 SprA-related family GNT-I PF03071.10 CDI87062.1 - 0.098 11.1 10.7 0.14 10.6 7.4 1.2 1 0 0 1 1 1 0 GNT-I family XRCC4 PF06632.7 CDI87062.1 - 0.77 8.5 19.7 0.88 8.3 13.7 1.1 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 RAP1 PF07218.6 CDI87062.1 - 0.8 7.7 21.3 1 7.3 14.8 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DUF853 PF05872.7 CDI87062.1 - 1 7.6 13.4 1 7.5 9.3 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) RR_TM4-6 PF06459.7 CDI87062.1 - 1.6 8.5 18.1 2.4 7.9 12.5 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF605 PF04652.11 CDI87062.1 - 1.9 7.7 46.7 2.4 7.4 32.4 1.0 1 0 0 1 1 1 0 Vta1 like DUF4207 PF13904.1 CDI87062.1 - 3.1 7.1 45.3 5.1 6.3 31.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4207) TFIIA PF03153.8 CDI87062.1 - 3.7 7.3 50.0 4.1 7.2 34.7 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit FUSC PF04632.7 CDI87062.1 - 4.6 5.5 6.4 5.4 5.3 4.4 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF1675 PF07897.6 CDI87062.1 - 5.5 6.7 34.6 9.5 5.9 24.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) DUF2232 PF09991.4 CDI87062.1 - 7.5 5.4 10.5 10 5.0 7.3 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) DUF1387 PF07139.6 CDI87062.1 - 8.5 5.8 31.6 9.6 5.7 21.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) SAGA-Tad1 PF12767.2 CDI87062.1 - 9 5.8 34.3 11 5.6 23.7 1.1 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit SR-25 PF10500.4 CDI87063.1 - 0.027 13.9 11.5 0.04 13.3 8.0 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF1117 PF06547.7 CDI87063.1 - 0.18 11.9 2.0 0.32 11.1 1.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1117) MRI PF15325.1 CDI87063.1 - 0.6 11.0 3.8 1.6 9.7 2.7 1.7 1 0 0 1 1 1 0 Modulator of retrovirus infection APC_CDC26 PF10471.4 CDI87063.1 - 1.1 10.0 4.9 2.3 8.9 3.4 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex APC subunit 1 RskA PF10099.4 CDI87064.1 - 0.014 15.1 35.2 0.1 12.3 7.9 2.0 1 1 1 2 2 2 0 Anti-sigma-K factor rskA DivIC PF04977.10 CDI87064.1 - 0.086 12.3 31.7 0.18 11.2 8.2 2.2 2 0 0 2 2 2 0 Septum formation initiator CD20 PF04103.10 CDI87064.1 - 0.09 12.7 4.3 2.1 8.2 0.2 2.1 2 0 0 2 2 2 0 CD20-like family EphA2_TM PF14575.1 CDI87064.1 - 0.12 12.8 6.4 3.5 8.1 0.3 2.3 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain DUF4097 PF13349.1 CDI87064.1 - 0.12 11.9 0.5 7.1 6.1 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4097) PepSY_2 PF13670.1 CDI87064.1 - 0.31 10.9 30.6 1.1 9.2 7.1 2.4 2 0 0 2 2 2 0 Peptidase propeptide and YPEB domain DUF3801 PF12687.2 CDI87064.1 - 0.49 9.9 19.0 0.69 9.4 13.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3801) DUF4010 PF13194.1 CDI87064.1 - 0.83 8.9 9.0 4.1 6.6 2.1 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4010) DUF966 PF06136.8 CDI87064.1 - 1.9 7.8 21.1 2.5 7.4 14.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Myf5 PF12232.3 CDI87064.1 - 2.1 9.0 4.9 17 6.1 0.2 2.2 2 0 0 2 2 2 0 Myogenic determination factor 5 RAB3GAP2_N PF14655.1 CDI87064.1 - 2.2 7.1 31.9 0.04 12.9 9.8 2.0 1 1 1 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus DUF2782 PF11191.3 CDI87064.1 - 4.2 7.3 19.6 0.68 9.9 2.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2782) PBP1_TM PF14812.1 CDI87064.1 - 4.5 7.6 7.7 4.8 7.5 0.7 2.2 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF4366 PF14283.1 CDI87064.1 - 5.3 6.4 21.0 12 5.2 14.5 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4366) Hid1 PF12722.2 CDI87064.1 - 6.2 4.3 21.6 7.3 4.1 15.0 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein PLRV_ORF5 PF01690.12 CDI87064.1 - 6.8 5.7 19.8 8 5.4 13.7 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein PAT1 PF09770.4 CDI87064.1 - 7.1 4.7 51.2 8.1 4.5 35.5 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 HA2 PF04408.18 CDI87064.1 - 7.7 6.6 10.3 10 6.1 1.3 2.2 2 0 0 2 2 2 0 Helicase associated domain (HA2) VIT1 PF01988.14 CDI87064.1 - 7.9 5.8 20.4 0.36 10.2 3.6 2.1 1 1 1 2 2 2 0 VIT family SAPS PF04499.10 CDI87064.1 - 9.8 4.6 19.9 12 4.3 13.8 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein SPG48 PF14764.1 CDI87065.1 - 1.4e-09 37.0 0.2 2.6e-09 36.1 0.1 1.4 1 0 0 1 1 1 1 AP-5 complex subunit, vesicle trafficking Shadoo PF14999.1 CDI87065.1 - 0.018 14.8 0.6 0.018 14.8 0.4 5.5 3 1 1 5 5 5 0 Shadow of prion protein, neuroprotective CAF-1_p150 PF11600.3 CDI87066.1 - 7.3e-06 25.5 18.5 8.4e-06 25.3 12.8 1.2 1 0 0 1 1 1 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal Med15 PF09606.5 CDI87066.1 - 0.0004 18.7 51.5 0.00048 18.4 35.7 1.1 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal AAA_11 PF13086.1 CDI87066.1 - 0.018 14.6 11.9 0.019 14.5 8.2 1.2 1 0 0 1 1 1 0 AAA domain SprA-related PF12118.3 CDI87066.1 - 0.021 14.1 42.7 0.028 13.7 29.6 1.2 1 0 0 1 1 1 0 SprA-related family MMR1 PF08505.5 CDI87066.1 - 0.044 13.8 18.3 0.071 13.1 12.7 1.3 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein GAGA_bind PF06217.7 CDI87066.1 - 0.1 12.5 13.7 0.11 12.3 9.5 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family TFIIA PF03153.8 CDI87066.1 - 0.18 11.6 37.3 0.21 11.4 25.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit HemX PF04375.9 CDI87066.1 - 0.21 10.1 37.2 0.3 9.6 25.8 1.2 1 0 0 1 1 1 0 HemX FHIPEP PF00771.15 CDI87066.1 - 0.25 9.6 15.7 0.32 9.2 10.8 1.1 1 0 0 1 1 1 0 FHIPEP family MRP-S31 PF15433.1 CDI87066.1 - 0.3 10.4 23.6 0.41 10.0 16.4 1.1 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 Macoilin PF09726.4 CDI87066.1 - 0.39 8.9 20.0 0.54 8.4 13.9 1.2 1 0 0 1 1 1 0 Transmembrane protein DUF2215 PF10225.4 CDI87066.1 - 0.44 9.9 6.5 0.58 9.5 4.5 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) Neur_chan_memb PF02932.11 CDI87066.1 - 0.45 10.3 10.3 0.5 10.1 7.1 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region IncA PF04156.9 CDI87066.1 - 0.47 10.0 40.2 1.5 8.3 27.9 1.8 1 1 0 1 1 1 0 IncA protein SOBP PF15279.1 CDI87066.1 - 0.5 10.6 16.7 0.59 10.4 11.5 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein Nucleoside_tran PF01733.13 CDI87066.1 - 0.59 9.2 3.0 0.71 8.9 2.1 1.3 1 0 0 1 1 1 0 Nucleoside transporter Atg14 PF10186.4 CDI87066.1 - 0.68 8.8 24.0 0.83 8.5 16.6 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Bac_GDH PF05088.7 CDI87066.1 - 0.75 7.1 20.1 0.85 6.9 13.9 1.0 1 0 0 1 1 1 0 Bacterial NAD-glutamate dehydrogenase DUF4220 PF13968.1 CDI87066.1 - 0.86 8.6 6.3 0.86 8.6 4.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4220) Exonuc_VII_L PF02601.10 CDI87066.1 - 0.99 8.5 20.4 1.5 7.9 14.1 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit NPBW PF15180.1 CDI87066.1 - 0.99 9.0 6.9 0.83 9.3 3.8 1.6 1 1 1 2 2 2 0 Neuropeptides B and W Hid1 PF12722.2 CDI87066.1 - 1.2 6.6 15.0 1.4 6.4 10.4 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein CDC27 PF09507.5 CDI87066.1 - 1.5 7.9 25.7 1.9 7.6 17.8 1.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Paramyxo_ncap PF00973.14 CDI87066.1 - 1.7 7.2 11.2 1.7 7.2 7.8 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein PAT1 PF09770.4 CDI87066.1 - 2 6.5 43.4 2.4 6.3 30.1 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 FliP PF00813.15 CDI87066.1 - 3.4 7.3 9.5 5.2 6.7 6.6 1.3 1 0 0 1 1 1 0 FliP family Baculo_PP31 PF05311.6 CDI87066.1 - 4.9 6.3 17.3 7.1 5.8 12.0 1.3 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) YfhO PF09586.5 CDI87066.1 - 5.9 4.7 10.4 6.2 4.7 7.2 1.0 1 0 0 1 1 1 0 Bacterial membrane protein YfhO Ndc1_Nup PF09531.5 CDI87066.1 - 8 4.7 13.6 9.1 4.5 9.4 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup SID-1_RNA_chan PF13965.1 CDI87066.1 - 8.5 4.4 10.9 9.5 4.2 7.6 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Med15 PF09606.5 CDI87067.1 - 0.67 8.0 46.2 0.73 7.9 32.0 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Caldesmon PF02029.10 CDI87067.1 - 1.4 7.2 50.1 1.8 6.9 34.7 1.0 1 0 0 1 1 1 0 Caldesmon PP2C PF00481.16 CDI87068.1 - 6.2e-14 52.0 0.4 6.2e-14 52.0 0.3 3.3 4 1 0 4 4 4 1 Protein phosphatase 2C Med15 PF09606.5 CDI87072.1 - 0.0017 16.6 13.6 0.0017 16.6 9.4 4.8 3 2 0 4 4 4 1 ARC105 or Med15 subunit of Mediator complex non-fungal Hydrolase_4 PF12146.3 CDI87072.1 - 0.027 14.2 0.0 5.6 6.8 0.0 2.4 2 0 0 2 2 2 0 Putative lysophospholipase DUF4557 PF15101.1 CDI87073.1 - 0.001 18.9 7.2 0.001 18.9 5.0 2.9 3 1 1 4 4 4 1 Domain of unknown function (DUF4557) Suf PF05843.9 CDI87073.1 - 0.001 18.8 5.6 0.001 18.8 3.9 2.9 3 1 0 3 3 3 1 Suppressor of forked protein (Suf) Spore_coat_CotO PF14153.1 CDI87073.1 - 0.0013 18.2 1.7 0.0013 18.2 1.2 2.2 2 0 0 2 2 2 1 Spore coat protein CotO 60KD_IMP PF02096.15 CDI87073.1 - 0.0056 16.3 6.5 0.012 15.2 4.5 1.5 1 0 0 1 1 1 1 60Kd inner membrane protein Plasmodium_Vir PF05795.6 CDI87073.1 - 0.014 14.5 0.6 0.038 13.2 0.4 1.6 1 0 0 1 1 1 0 Plasmodium vivax Vir protein PBP1_TM PF14812.1 CDI87073.1 - 0.024 14.9 0.2 0.076 13.3 0.1 1.8 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF912 PF06024.7 CDI87073.1 - 0.027 14.4 0.2 0.027 14.4 0.1 2.5 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Ofd1_CTDD PF10637.4 CDI87073.1 - 0.059 12.4 2.0 0.097 11.7 1.4 1.2 1 0 0 1 1 1 0 Oxoglutarate and iron-dependent oxygenase degradation C-term DUF3270 PF11674.3 CDI87073.1 - 0.08 12.9 1.3 0.2 11.6 0.9 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3270) DUF3675 PF12428.3 CDI87073.1 - 1.2 9.3 5.0 0.31 11.3 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3675) Porphobil_deam PF01379.15 CDI87074.1 - 1.2e-17 63.5 18.3 3.4e-11 42.5 0.8 5.6 4 2 1 5 5 5 4 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.10 CDI87074.1 - 4.2e-13 49.1 3.3 4.2e-13 49.1 2.3 2.6 2 1 0 2 2 2 1 Porphobilinogen deaminase, C-terminal domain FimP PF09766.4 CDI87074.1 - 0.00076 18.6 23.6 0.032 13.2 8.7 2.3 2 0 0 2 2 2 2 Fms-interacting protein Peptidase_S49_N PF08496.5 CDI87074.1 - 0.0022 17.7 10.3 0.14 11.9 1.3 2.8 3 0 0 3 3 3 2 Peptidase family S49 N-terminal Ribosomal_60s PF00428.14 CDI87074.1 - 0.0036 17.6 3.6 0.0036 17.6 2.5 8.6 7 2 1 8 8 8 2 60s Acidic ribosomal protein cwf18 PF08315.7 CDI87074.1 - 0.019 15.3 1.5 0.019 15.3 1.1 3.2 3 0 0 3 3 3 0 cwf18 pre-mRNA splicing factor Activator_LAG-3 PF11498.3 CDI87074.1 - 0.027 13.2 63.8 0.21 10.2 18.9 3.3 3 0 0 3 3 3 0 Transcriptional activator LAG-3 zf-DHHC PF01529.15 CDI87074.1 - 0.1 11.9 1.4 1.4 8.2 0.0 2.2 2 0 0 2 2 2 0 DHHC palmitoyltransferase Spore_coat_CotO PF14153.1 CDI87074.1 - 0.18 11.2 15.4 0.26 10.7 2.2 2.6 2 0 0 2 2 2 0 Spore coat protein CotO Serinc PF03348.10 CDI87074.1 - 0.21 10.2 11.6 1.3 7.6 2.2 2.3 2 0 0 2 2 2 0 Serine incorporator (Serinc) DUF3373 PF11853.3 CDI87074.1 - 0.33 9.4 14.1 1.2 7.5 1.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3373) AUX_IAA PF02309.11 CDI87074.1 - 0.79 9.4 8.6 0.56 9.9 0.8 2.9 3 0 0 3 3 3 0 AUX/IAA family DUF4518 PF15008.1 CDI87074.1 - 2.1 7.3 11.8 2.7 6.9 0.5 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4518) IL3 PF02059.10 CDI87074.1 - 2.2 8.3 9.6 0.12 12.4 0.2 3.3 4 0 0 4 4 3 0 Interleukin-3 Pex16 PF08610.5 CDI87074.1 - 2.3 7.1 16.0 1.5 7.7 1.8 2.5 2 0 0 2 2 2 0 Peroxisomal membrane protein (Pex16) eIF_4EBP PF05456.6 CDI87074.1 - 3.9 7.2 16.9 0.34 10.6 1.3 2.9 3 0 0 3 3 3 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) Hep_59 PF07052.6 CDI87074.1 - 4.1 7.8 18.2 1.9 8.9 1.2 3.5 4 0 0 4 4 4 0 Hepatocellular carcinoma-associated antigen 59 SprA-related PF12118.3 CDI87075.1 - 0.0022 17.3 12.3 0.0022 17.3 8.6 7.2 5 1 2 7 7 7 3 SprA-related family Med15 PF09606.5 CDI87075.1 - 0.0022 16.2 26.1 0.0022 16.2 18.1 4.7 3 1 1 5 5 5 3 ARC105 or Med15 subunit of Mediator complex non-fungal UPF0564 PF10595.4 CDI87075.1 - 0.0027 16.6 9.3 0.0027 16.6 6.4 5.2 5 0 0 5 5 5 1 Uncharacterised protein family UPF0564 DUF3801 PF12687.2 CDI87075.1 - 0.011 15.3 1.1 0.011 15.3 0.8 5.2 5 0 0 5 5 5 0 Protein of unknown function (DUF3801) Topoisom_I_N PF02919.10 CDI87075.1 - 0.017 14.3 0.5 0.017 14.3 0.4 4.5 5 0 0 5 5 5 0 Eukaryotic DNA topoisomerase I, DNA binding fragment Polysacc_synt_2 PF02719.10 CDI87075.1 - 0.64 8.8 8.6 0.043 12.7 1.0 2.5 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein FimP PF09766.4 CDI87075.1 - 1.2 8.1 88.4 0.39 9.7 10.2 5.6 5 0 0 5 5 5 0 Fms-interacting protein AAA_11 PF13086.1 CDI87075.1 - 4.7 6.7 49.9 0.16 11.5 5.7 4.5 3 1 1 4 4 4 0 AAA domain Ribosomal_L18_c PF14204.1 CDI87076.1 - 2.1e-32 111.5 7.1 3.1e-32 110.9 4.9 1.3 1 0 0 1 1 1 1 Ribosomal L18 C-terminal region Ribosomal_L18p PF00861.17 CDI87076.1 - 1.1e-20 74.0 0.0 2.2e-20 73.0 0.0 1.5 1 0 0 1 1 1 1 Ribosomal L18p/L5e family Choline_sulf_C PF12411.3 CDI87076.1 - 0.059 13.1 0.4 2.5 8.0 0.1 2.5 2 0 0 2 2 2 0 Choline sulfatase enzyme C terminal Sod_Ni PF09055.6 CDI87076.1 - 0.51 10.7 2.6 1.6 9.1 0.9 2.0 1 1 1 2 2 2 0 Nickel-containing superoxide dismutase GCC2_GCC3 PF07699.8 CDI87078.1 - 7.6e-23 79.8 111.3 6e-07 28.9 3.9 12.1 12 1 0 12 12 12 9 GCC2 and GCC3 HALZ PF02183.13 CDI87078.1 - 0.38 10.5 1.3 0.73 9.6 0.9 1.5 1 0 0 1 1 1 0 Homeobox associated leucine zipper Cation_efflux PF01545.16 CDI87078.1 - 0.87 8.6 0.8 1.6 7.7 0.6 1.3 1 0 0 1 1 1 0 Cation efflux family AAA_27 PF13514.1 CDI87078.1 - 1.2 6.6 5.4 1.8 6.1 3.7 1.1 1 0 0 1 1 1 0 AAA domain CALCOCO1 PF07888.6 CDI87078.1 - 5.9 5.0 2.9 10 4.2 2.0 1.3 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like DUF669 PF05037.8 CDI87078.1 - 7 6.5 0.0 16 5.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF669) Amino_oxidase PF01593.19 CDI87079.1 - 3.1e-34 118.8 9.6 9.3e-27 94.1 0.1 3.0 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 CDI87079.1 - 1.8e-11 43.8 0.3 1.8e-11 43.8 0.2 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 CDI87079.1 - 1.3e-05 25.1 0.4 3.5e-05 23.7 0.3 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 CDI87079.1 - 5.7e-05 22.3 0.1 0.00012 21.2 0.1 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.1 CDI87079.1 - 0.00019 21.5 0.2 0.00019 21.5 0.1 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 CDI87079.1 - 0.00032 21.0 0.5 0.00074 19.8 0.3 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 CDI87079.1 - 0.0044 15.5 0.8 0.0044 15.5 0.5 2.3 2 0 0 2 2 2 1 HI0933-like protein AlaDh_PNT_C PF01262.16 CDI87079.1 - 0.0058 16.2 0.2 0.014 14.9 0.1 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Strep_67kDa_ant PF06100.6 CDI87079.1 - 2.1 6.6 0.1 4 5.6 0.0 1.4 1 0 0 1 1 1 0 Streptococcal 67 kDa myosin-cross-reactive antigen like family PRP1_N PF06424.7 CDI87080.1 - 2.1e-49 167.2 2.4 3.3e-40 137.5 0.4 2.6 2 0 0 2 2 2 2 PRP1 splicing factor, N-terminal TPR_14 PF13428.1 CDI87080.1 - 3.4e-31 104.8 28.7 0.00073 19.9 0.3 14.9 6 3 9 15 15 15 9 Tetratricopeptide repeat TPR_19 PF14559.1 CDI87080.1 - 6e-19 68.1 19.2 0.00064 20.0 0.0 9.5 6 2 4 10 10 10 4 Tetratricopeptide repeat TPR_11 PF13414.1 CDI87080.1 - 4.7e-16 58.1 8.9 0.0092 15.6 0.0 9.1 5 3 6 11 11 11 3 TPR repeat TPR_16 PF13432.1 CDI87080.1 - 3.2e-14 53.1 17.9 0.013 16.1 0.0 8.9 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_2 PF07719.12 CDI87080.1 - 9.2e-08 31.4 12.5 3.8 7.6 0.0 10.4 12 0 0 12 12 12 2 Tetratricopeptide repeat TPR_12 PF13424.1 CDI87080.1 - 9.5e-07 28.6 6.1 1.1 9.1 0.4 6.8 6 1 1 7 7 7 2 Tetratricopeptide repeat ChAPs PF09295.5 CDI87080.1 - 0.0002 20.2 6.8 0.027 13.2 0.0 3.9 2 1 2 4 4 4 2 ChAPs (Chs5p-Arf1p-binding proteins) Suf PF05843.9 CDI87080.1 - 0.00032 20.5 0.0 20 4.7 0.0 4.8 2 2 0 3 3 3 0 Suppressor of forked protein (Suf) TPR_8 PF13181.1 CDI87080.1 - 0.00047 19.7 0.9 1.7 8.6 0.0 6.1 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_17 PF13431.1 CDI87080.1 - 0.0034 17.4 6.0 42 4.6 0.0 8.5 13 1 1 14 14 9 0 Tetratricopeptide repeat DUF3808 PF10300.4 CDI87080.1 - 0.015 13.9 3.2 0.67 8.4 0.1 4.1 4 1 1 5 5 5 0 Protein of unknown function (DUF3808) TPR_21 PF09976.4 CDI87080.1 - 0.06 13.2 16.5 0.027 14.4 1.9 4.6 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.1 CDI87080.1 - 0.073 13.5 14.4 27 5.5 0.1 7.9 10 0 0 10 10 8 0 Tetratricopeptide repeat TPR_1 PF00515.23 CDI87080.1 - 0.28 10.8 1.7 2.9 7.6 0.0 3.8 4 0 0 4 4 3 0 Tetratricopeptide repeat YebG PF07130.7 CDI87081.1 - 0.049 13.3 0.3 0.12 12.0 0.2 1.6 1 0 0 1 1 1 0 YebG protein DUF1900 PF08954.6 CDI87082.1 - 3.7e-22 78.2 0.0 2.6e-17 62.6 0.0 2.7 2 1 1 3 3 3 2 Domain of unknown function (DUF1900) WD40 PF00400.27 CDI87082.1 - 7.8e-16 57.2 5.0 2.2e-10 40.0 0.0 4.2 4 0 0 4 4 4 2 WD domain, G-beta repeat Baculo_PEP_C PF04513.7 CDI87082.1 - 0.0013 18.5 6.8 0.014 15.2 0.3 2.4 1 1 1 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1899 PF08953.6 CDI87082.1 - 0.0018 17.8 0.0 0.0034 16.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) Tropomyosin_1 PF12718.2 CDI87082.1 - 0.009 15.8 29.0 0.022 14.5 20.0 1.6 1 1 0 1 1 1 1 Tropomyosin like AAA_13 PF13166.1 CDI87082.1 - 0.024 13.1 11.5 0.038 12.4 7.9 1.2 1 0 0 1 1 1 0 AAA domain Myosin_tail_1 PF01576.14 CDI87082.1 - 0.056 11.1 26.5 0.61 7.7 7.5 1.6 1 1 0 1 1 1 0 Myosin tail GAS PF13851.1 CDI87082.1 - 0.057 12.6 21.5 7.8 5.6 16.7 2.3 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding Lebercilin PF15619.1 CDI87082.1 - 0.12 11.7 23.1 0.19 11.1 16.0 1.2 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease CENP-Q PF13094.1 CDI87082.1 - 0.13 12.2 24.3 0.53 10.2 16.8 1.9 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit CENP-F_leu_zip PF10473.4 CDI87082.1 - 0.16 11.8 25.0 0.13 12.0 16.3 1.6 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 BLOC1_2 PF10046.4 CDI87082.1 - 0.2 11.8 15.8 6.3 6.9 5.1 2.7 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4200 PF13863.1 CDI87082.1 - 0.25 11.3 22.4 0.079 12.9 5.3 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) TPR_MLP1_2 PF07926.7 CDI87082.1 - 0.37 10.5 25.5 2 8.1 10.2 2.2 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Phage_GP20 PF06810.6 CDI87082.1 - 0.81 9.1 24.1 4.1 6.8 2.1 3.0 1 1 2 3 3 3 0 Phage minor structural protein GP20 WXG100 PF06013.7 CDI87082.1 - 0.85 9.6 13.0 0.1 12.6 3.7 2.7 1 1 0 2 2 2 0 Proteins of 100 residues with WXG Med9 PF07544.8 CDI87082.1 - 1.3 8.7 20.2 1.1 9.0 1.7 4.3 3 1 1 4 4 4 0 RNA polymerase II transcription mediator complex subunit 9 IncA PF04156.9 CDI87082.1 - 1.7 8.2 27.8 0.79 9.2 6.9 2.2 1 1 1 2 2 2 0 IncA protein Peptidase_S64 PF08192.6 CDI87082.1 - 1.7 6.9 8.3 2.3 6.4 5.7 1.1 1 0 0 1 1 1 0 Peptidase family S64 CemA PF03040.9 CDI87082.1 - 2.6 7.6 3.4 4.2 6.9 2.4 1.3 1 0 0 1 1 1 0 CemA family Fib_alpha PF08702.5 CDI87082.1 - 3.6 7.7 15.1 2.8 8.0 3.8 2.4 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Pkip-1 PF06878.6 CDI87082.1 - 3.6 7.4 13.0 23 4.8 4.7 3.1 1 1 1 2 2 2 0 Pkip-1 protein TMF_DNA_bd PF12329.3 CDI87082.1 - 5.7 6.8 33.9 2.7 7.8 3.0 3.6 1 1 2 3 3 3 0 TATA element modulatory factor 1 DNA binding Mnd1 PF03962.10 CDI87082.1 - 5.8 6.5 22.0 5.8 6.5 9.9 2.7 1 1 1 2 2 2 0 Mnd1 family Striatin PF08232.7 CDI87082.1 - 6 7.1 21.5 30 4.9 6.3 2.8 1 1 1 2 2 2 0 Striatin family FH2 PF02181.18 CDI87082.1 - 9 5.0 17.0 31 3.3 3.5 2.1 1 1 1 2 2 2 0 Formin Homology 2 Domain DUF1768 PF08719.6 CDI87083.1 - 0.087 12.5 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1768) SLX9 PF15341.1 CDI87083.1 - 0.13 12.7 4.6 0.47 10.9 3.2 2.0 1 0 0 1 1 1 0 Ribosome biogenesis protein SLX9 Nop25 PF09805.4 CDI87083.1 - 2.1 8.4 6.8 5 7.2 4.7 1.6 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) Striatin PF08232.7 CDI87083.1 - 6.5 7.0 10.3 0.82 9.9 4.1 1.8 2 0 0 2 2 2 0 Striatin family Syntaxin_2 PF14523.1 CDI87083.1 - 8 6.5 7.4 2.3 8.3 1.6 2.3 2 0 0 2 2 2 0 Syntaxin-like protein WD40 PF00400.27 CDI87084.1 - 3.8e-22 77.3 7.6 3.5e-06 26.6 0.2 6.7 7 0 0 7 7 7 5 WD domain, G-beta repeat V-ATPase_G PF03179.10 CDI87085.1 - 3.7e-26 91.4 7.6 4.4e-26 91.2 5.3 1.0 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit ADPrib_exo_Tox PF03496.9 CDI87085.1 - 0.026 13.7 0.3 0.027 13.6 0.2 1.1 1 0 0 1 1 1 0 ADP-ribosyltransferase exoenzyme HrpE PF06188.7 CDI87085.1 - 0.066 12.9 3.2 0.17 11.6 2.3 1.7 1 1 0 1 1 1 0 HrpE/YscL/FliH and V-type ATPase subunit E ATP-synt_B PF00430.13 CDI87085.1 - 0.16 11.7 9.1 0.21 11.3 6.1 1.3 1 1 0 1 1 1 0 ATP synthase B/B' CF(0) WD40 PF00400.27 CDI87086.1 - 2.4e-36 122.3 14.3 4.2e-09 35.9 0.3 7.1 6 1 0 6 6 6 6 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 CDI87086.1 - 0.076 11.2 0.1 0.28 9.4 0.0 1.9 3 0 0 3 3 3 0 Cytochrome D1 heme domain Ribosomal_S5 PF00333.15 CDI87087.1 - 1.7e-28 98.1 0.5 4.4e-28 96.8 0.2 1.8 2 0 0 2 2 2 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.10 CDI87087.1 - 1.7e-21 75.2 0.0 3.5e-21 74.2 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Ribosomal_S17 PF00366.15 CDI87088.1 - 3.2e-26 91.1 1.8 4.5e-26 90.6 1.3 1.2 1 0 0 1 1 1 1 Ribosomal protein S17 PHD PF00628.24 CDI87089.1 - 9.4e-09 34.8 6.5 9.4e-09 34.8 4.5 1.8 2 0 0 2 2 2 1 PHD-finger zf-PHD-like PF15446.1 CDI87089.1 - 0.15 11.3 9.9 0.42 9.8 3.0 3.1 3 1 1 4 4 4 0 PHD/FYVE-zinc-finger like domain PHD_2 PF13831.1 CDI87089.1 - 8.5 5.7 10.6 0.28 10.5 3.0 1.9 2 0 0 2 2 2 0 PHD-finger Nop25 PF09805.4 CDI87091.1 - 1.1e-13 51.4 9.1 1.1e-13 51.4 6.3 1.7 2 0 0 2 2 2 1 Nucleolar protein 12 (25kDa) 7TMR-HDED PF07697.6 CDI87091.1 - 0.0025 17.5 3.0 0.0025 17.5 2.1 1.4 1 1 0 1 1 1 1 7TM-HD extracellular Glyco_trans_1_2 PF13524.1 CDI87091.1 - 6.9 7.0 7.3 14 6.0 5.1 1.5 1 0 0 1 1 1 0 Glycosyl transferases group 1 M60-like PF13402.1 CDI87093.1 - 0.23 10.2 11.1 0.095 11.5 2.7 2.3 1 1 0 2 2 2 0 Peptidase M60-like family MSA-2c PF12238.3 CDI87093.1 - 0.39 10.3 14.9 0.23 11.1 8.3 1.8 1 1 1 2 2 2 0 Merozoite surface antigen 2c Nucleo_P87 PF07267.6 CDI87093.1 - 3.8 6.0 22.4 4.4 5.8 15.6 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 ALMT PF11744.3 CDI87093.1 - 6.5 5.2 6.4 7.9 5.0 4.5 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter PAT1 PF09770.4 CDI87093.1 - 6.6 4.8 52.7 7.8 4.5 36.5 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SPX PF03105.14 CDI87093.1 - 7.3 6.2 23.8 9 5.9 16.5 1.1 1 0 0 1 1 1 0 SPX domain eIF-3_zeta PF05091.7 CDI87093.1 - 9.4 4.7 21.5 12 4.3 14.9 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) PAT1 PF09770.4 CDI87094.1 - 0.43 8.7 37.9 0.69 8.0 26.3 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Dicty_REP PF05086.7 CDI87094.1 - 4.7 4.8 4.7 7.1 4.2 3.2 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein RRM_5 PF13893.1 CDI87095.1 - 0.00066 19.4 0.0 0.0017 18.1 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CDI87095.1 - 0.0061 16.5 0.0 0.011 15.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF998 PF06197.8 CDI87097.1 - 0.068 12.4 6.5 0.087 12.1 4.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF998) Claudin_2 PF13903.1 CDI87097.1 - 2.4 7.7 12.4 0.63 9.7 5.8 1.8 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction Flu_PB1 PF00602.12 CDI87099.1 - 0.09 10.4 0.0 0.15 9.7 0.0 1.2 1 0 0 1 1 1 0 Influenza RNA-dependent RNA polymerase subunit PB1 Ribosomal_L27e PF01777.13 CDI87100.1 - 9.2e-24 83.3 2.5 1.2e-23 83.0 1.7 1.1 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.24 CDI87100.1 - 0.0009 18.8 1.4 0.0017 17.9 1.0 1.5 1 0 0 1 1 1 1 KOW motif PARP PF00644.15 CDI87101.1 - 9e-57 191.8 0.0 1.6e-56 191.0 0.0 1.4 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.9 CDI87101.1 - 2.2e-30 105.0 2.2 3.5e-30 104.3 1.5 1.3 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain WGR PF05406.10 CDI87101.1 - 3.7e-11 42.8 1.4 5.9e-11 42.1 0.4 1.8 2 0 0 2 2 2 1 WGR domain PADR1 PF08063.7 CDI87101.1 - 2.2e-09 36.5 0.2 5.1e-09 35.3 0.1 1.6 1 0 0 1 1 1 1 PADR1 (NUC008) domain BRCT PF00533.21 CDI87101.1 - 2.5e-08 33.9 0.0 7.2e-08 32.4 0.0 1.8 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 CDI87101.1 - 3.9e-06 26.6 0.0 1.1e-05 25.1 0.0 1.8 1 0 0 1 1 1 1 twin BRCT domain TMEM52 PF14979.1 CDI87103.1 - 0.21 11.4 0.1 0.21 11.4 0.1 1.7 2 0 0 2 2 2 0 Transmembrane 52 Cep57_MT_bd PF06657.8 CDI87103.1 - 0.55 10.2 9.2 0.08 12.8 2.2 2.7 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 APG6 PF04111.7 CDI87104.1 - 9.9 5.0 16.7 4.7 6.1 8.9 2.2 2 0 0 2 2 2 0 Autophagy protein Apg6 TraT PF05818.7 CDI87105.1 - 0.64 9.4 6.9 0.83 9.0 4.8 1.2 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein DUF533 PF04391.7 CDI87105.1 - 0.7 9.2 8.5 0.76 9.1 5.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF533) PsaN PF05479.6 CDI87105.1 - 1.5 8.7 13.2 1.8 8.5 9.1 1.2 1 0 0 1 1 1 0 Photosystem I reaction centre subunit N (PSAN or PSI-N) MSP1_C PF07462.6 CDI87105.1 - 5.2 5.3 9.2 5.7 5.1 6.4 1.1 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus DUF2217 PF10265.4 CDI87105.1 - 5.9 5.5 9.1 6.7 5.3 6.3 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) DUF1183 PF06682.7 CDI87105.1 - 6.5 6.2 10.4 6.6 6.2 7.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) Ribosomal_60s PF00428.14 CDI87107.1 - 0.00032 21.0 15.7 0.00032 21.0 10.9 27.0 10 5 10 21 21 21 2 60s Acidic ribosomal protein LMBR1 PF04791.11 CDI87107.1 - 0.0021 16.6 1.0 0.0021 16.6 0.7 8.2 5 3 2 7 7 7 1 LMBR1-like membrane protein Herpes_UL87 PF03043.9 CDI87107.1 - 0.17 10.2 0.0 0.17 10.2 0.0 6.7 3 2 1 6 6 6 0 Herpesvirus UL87 family PAT1 PF09770.4 CDI87108.1 - 6.5 4.8 73.3 0.28 9.3 37.5 2.1 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 UPF0564 PF10595.4 CDI87109.1 - 1.9e-05 23.7 14.9 1.9e-05 23.7 10.3 4.2 4 0 0 4 4 4 2 Uncharacterised protein family UPF0564 RskA PF10099.4 CDI87110.1 - 0.07 12.8 8.7 0.074 12.7 6.0 1.1 1 0 0 1 1 1 0 Anti-sigma-K factor rskA Plant_all_beta PF10532.4 CDI87110.1 - 0.7 9.9 3.7 0.86 9.6 2.6 1.3 1 0 0 1 1 1 0 Plant specific N-all beta domain Alpha_GJ PF03229.8 CDI87110.1 - 2.9 8.2 9.5 3.6 7.9 6.6 1.2 1 0 0 1 1 1 0 Alphavirus glycoprotein J MRP-S31 PF15433.1 CDI87110.1 - 4.6 6.5 15.1 5.2 6.3 10.5 1.1 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 DUF2360 PF10152.4 CDI87110.1 - 6 7.1 16.9 7.6 6.8 11.7 1.1 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) SprA-related PF12118.3 CDI87110.1 - 6.2 6.0 31.8 6.6 5.9 22.1 1.0 1 0 0 1 1 1 0 SprA-related family MGC-24 PF05283.6 CDI87110.1 - 7.1 6.3 14.0 8.5 6.1 9.7 1.1 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24) IncA PF04156.9 CDI87111.1 - 0.44 10.1 74.7 0.015 14.8 14.3 2.6 2 0 0 2 2 2 0 IncA protein DUF1772 PF08592.6 CDI87111.1 - 0.59 9.8 14.4 6.5 6.4 7.9 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1772) Zip PF02535.17 CDI87114.1 - 0.019 14.0 5.7 0.022 13.7 4.0 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter DUF3357 PF11837.3 CDI87114.1 - 0.019 14.7 0.4 0.019 14.7 0.3 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF3357) LNP1 PF15419.1 CDI87114.1 - 0.026 14.6 10.6 0.03 14.4 7.4 1.1 1 0 0 1 1 1 0 Leukemia NUP98 fusion partner 1 Trypan_PARP PF05887.6 CDI87114.1 - 0.069 12.9 1.4 0.096 12.4 1.0 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Daxx PF03344.10 CDI87114.1 - 0.14 10.6 20.3 0.16 10.4 14.1 1.0 1 0 0 1 1 1 0 Daxx Family DUF2217 PF10265.4 CDI87114.1 - 0.17 10.6 4.7 0.19 10.4 3.3 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) ADP_ribosyl_GH PF03747.9 CDI87114.1 - 0.18 11.5 3.6 0.2 11.4 2.5 1.1 1 0 0 1 1 1 0 ADP-ribosylglycohydrolase LpxK PF02606.9 CDI87114.1 - 0.39 9.6 5.5 0.45 9.4 3.8 1.1 1 0 0 1 1 1 0 Tetraacyldisaccharide-1-P 4'-kinase Serinc PF03348.10 CDI87114.1 - 0.44 9.1 12.4 0.48 9.0 8.6 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) CDC45 PF02724.9 CDI87114.1 - 0.45 8.4 15.7 0.51 8.3 10.9 1.1 1 0 0 1 1 1 0 CDC45-like protein Pal1 PF08316.6 CDI87114.1 - 0.57 10.6 10.2 0.74 10.2 7.0 1.3 1 1 0 1 1 1 0 Pal1 cell morphology protein CoA_transf_3 PF02515.12 CDI87114.1 - 0.82 8.8 5.8 1 8.5 4.0 1.3 1 0 0 1 1 1 0 CoA-transferase family III ETRAMP PF09716.5 CDI87114.1 - 0.87 9.5 0.1 0.87 9.5 0.0 2.1 1 1 1 2 2 1 0 Malarial early transcribed membrane protein (ETRAMP) FAM101 PF15068.1 CDI87114.1 - 1.1 8.6 5.8 3.5 7.0 4.0 1.8 1 1 0 1 1 1 0 FAM101 family Prog_receptor PF02161.10 CDI87114.1 - 1.1 7.9 13.9 1.5 7.6 9.6 1.2 1 0 0 1 1 1 0 Progesterone receptor Raftlin PF15250.1 CDI87114.1 - 1.2 7.5 16.0 1.4 7.4 11.1 1.1 1 0 0 1 1 1 0 Raftlin TRAP_alpha PF03896.11 CDI87114.1 - 1.3 8.0 6.3 1.4 7.8 4.4 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit VID27 PF08553.5 CDI87114.1 - 1.6 6.8 11.1 1.6 6.8 7.7 1.1 1 0 0 1 1 1 0 VID27 cytoplasmic protein AAA_11 PF13086.1 CDI87114.1 - 1.7 8.1 13.6 2.5 7.6 9.4 1.2 1 0 0 1 1 1 0 AAA domain Nucleoside_tran PF01733.13 CDI87114.1 - 1.8 7.6 4.8 1.9 7.6 3.3 1.2 1 0 0 1 1 1 0 Nucleoside transporter SAGA-Tad1 PF12767.2 CDI87114.1 - 2 8.0 20.0 2.9 7.5 13.9 1.2 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit CD20 PF04103.10 CDI87114.1 - 2.4 8.0 7.8 9.7 6.1 5.4 2.1 1 1 0 1 1 1 0 CD20-like family RskA PF10099.4 CDI87114.1 - 2.7 7.6 21.5 6.8 6.3 14.9 1.6 1 1 0 1 1 1 0 Anti-sigma-K factor rskA Presenilin PF01080.12 CDI87114.1 - 3 6.5 14.8 3.1 6.5 10.3 1.0 1 0 0 1 1 1 0 Presenilin DUF2232 PF09991.4 CDI87114.1 - 3.3 6.6 9.9 1.9 7.4 5.5 1.5 1 1 1 2 2 2 0 Predicted membrane protein (DUF2232) NPR3 PF03666.8 CDI87114.1 - 3.6 6.0 15.6 4 5.8 10.8 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Hid1 PF12722.2 CDI87114.1 - 3.8 5.0 18.7 4.1 4.9 12.9 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein PBP1_TM PF14812.1 CDI87114.1 - 4.6 7.6 9.3 0.55 10.5 2.9 1.9 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal R_equi_Vir PF05526.6 CDI87114.1 - 4.8 6.7 9.9 6.7 6.3 6.9 1.3 1 0 0 1 1 1 0 Rhodococcus equi virulence-associated protein SpoVR PF04293.8 CDI87114.1 - 4.9 5.4 17.0 6 5.1 11.8 1.1 1 0 0 1 1 1 0 SpoVR like protein Cellulose_synt PF03552.9 CDI87114.1 - 5.3 5.2 5.7 5.3 5.1 4.0 1.1 1 0 0 1 1 1 0 Cellulose synthase DDRGK PF09756.4 CDI87114.1 - 5.4 6.3 27.0 0.24 10.7 12.4 2.0 2 0 0 2 2 2 0 DDRGK domain GAGA_bind PF06217.7 CDI87114.1 - 6.6 6.6 17.3 7.2 6.4 12.0 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family DUF3824 PF12868.2 CDI87114.1 - 6.7 7.6 13.9 2.2 9.2 7.6 1.6 1 1 0 1 1 1 0 Domain of unknwon function (DUF3824) Tom37_C PF11801.3 CDI87114.1 - 6.9 6.5 17.5 8.9 6.1 12.1 1.2 1 0 0 1 1 1 0 Tom37 C-terminal domain SID-1_RNA_chan PF13965.1 CDI87114.1 - 7.8 4.5 7.5 8.2 4.4 5.2 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DUF4613 PF15390.1 CDI87114.1 - 8.3 4.4 17.3 9.3 4.2 12.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) DUF2828 PF11443.3 CDI87114.1 - 8.8 4.4 11.2 10 4.1 7.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) DUF844 PF05815.6 CDI87114.1 - 9 5.0 13.3 13 4.5 9.2 1.3 1 0 0 1 1 1 0 Baculovirus protein of unknown function (DUF844) DDHD PF02862.12 CDI87114.1 - 9.9 5.8 19.8 15 5.2 13.7 1.2 1 0 0 1 1 1 0 DDHD domain Zip PF02535.17 CDI87116.1 - 0.56 9.1 14.3 0.67 8.9 9.9 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter DUF3464 PF11947.3 CDI87116.1 - 3.1 7.2 13.6 3.9 6.9 9.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) GAGA_bind PF06217.7 CDI87116.1 - 3.5 7.5 18.6 3.5 7.5 12.9 1.0 1 0 0 1 1 1 0 GAGA binding protein-like family 2OG-FeII_Oxy_5 PF13759.1 CDI87116.1 - 4.9 7.4 12.7 7.3 6.9 8.8 1.2 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase FAM91_C PF14648.1 CDI87116.1 - 5 5.8 9.6 4.9 5.8 6.7 1.0 1 0 0 1 1 1 0 FAM91 C-terminus Baculo_PP31 PF05311.6 CDI87116.1 - 6.1 6.0 18.3 6.1 6.0 12.7 1.1 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) ALG3 PF05208.8 CDI87116.1 - 9.7 5.3 6.5 11 5.0 4.5 1.1 1 0 0 1 1 1 0 ALG3 protein Citrate_synt PF00285.16 CDI87117.1 - 0.04 12.6 4.1 0.047 12.4 2.8 1.0 1 0 0 1 1 1 0 Citrate synthase PUD PF03714.9 CDI87117.1 - 0.061 13.4 1.7 0.084 13.0 1.2 1.2 1 0 0 1 1 1 0 Bacterial pullanase-associated domain Herpes_UL87 PF03043.9 CDI87117.1 - 0.11 10.8 10.0 0.12 10.7 6.9 1.0 1 0 0 1 1 1 0 Herpesvirus UL87 family Zip PF02535.17 CDI87117.1 - 0.16 10.9 2.5 0.22 10.5 1.7 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter DUF1345 PF07077.6 CDI87117.1 - 0.29 10.6 4.8 0.14 11.6 0.5 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1345) Hid1 PF12722.2 CDI87117.1 - 0.55 7.8 15.8 0.63 7.6 10.9 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein MDFI PF15316.1 CDI87117.1 - 1.1 9.2 9.4 1.4 8.9 6.5 1.1 1 0 0 1 1 1 0 MyoD family inhibitor DUF4484 PF14831.1 CDI87117.1 - 1.5 8.9 9.4 2.1 8.3 6.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4484) FLO_LFY PF01698.11 CDI87117.1 - 1.5 7.5 16.4 1.9 7.2 11.4 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein Presenilin PF01080.12 CDI87117.1 - 1.5 7.5 7.6 1.9 7.2 5.3 1.2 1 0 0 1 1 1 0 Presenilin PAT1 PF09770.4 CDI87117.1 - 1.6 6.8 43.2 1.8 6.7 29.9 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TFIIA PF03153.8 CDI87117.1 - 2 8.2 27.9 2.4 7.9 19.3 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit HCO3_cotransp PF00955.16 CDI87117.1 - 2.1 6.8 7.6 2.6 6.5 5.3 1.1 1 0 0 1 1 1 0 HCO3- transporter family GAGA_bind PF06217.7 CDI87117.1 - 2.2 8.1 17.0 2.6 7.9 11.8 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family Neur_chan_memb PF02932.11 CDI87117.1 - 2.7 7.8 13.2 3 7.6 9.1 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region PBP1_TM PF14812.1 CDI87117.1 - 3.1 8.1 7.6 2.2 8.6 2.4 2.2 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal BRF1 PF07741.8 CDI87117.1 - 3.8 7.7 15.4 2.7 8.2 4.1 2.3 2 0 0 2 2 2 0 Brf1-like TBP-binding domain SID-1_RNA_chan PF13965.1 CDI87117.1 - 4 5.4 9.2 4.5 5.3 6.4 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Mem_trans PF03547.13 CDI87117.1 - 5.7 5.1 9.1 6.4 4.9 6.3 1.1 1 0 0 1 1 1 0 Membrane transport protein Rxt3 PF08642.5 CDI87117.1 - 6 7.1 12.1 19 5.5 8.4 1.7 1 1 1 2 2 2 0 Histone deacetylation protein Rxt3 DUF4064 PF13273.1 CDI87117.1 - 6.9 6.8 9.6 7.2 6.7 0.5 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF4064) DUF3043 PF11241.3 CDI87117.1 - 7.7 6.0 10.1 2.6 7.5 1.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3043) Peroxin-13_N PF04088.8 CDI87117.1 - 9.8 6.1 14.8 0.91 9.4 4.1 2.0 1 1 1 2 2 2 0 Peroxin 13, N-terminal region DUF2845 PF11006.3 CDI87120.1 - 0.073 12.9 0.7 3.3 7.5 0.2 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2845) DUF1754 PF08555.5 CDI87123.1 - 0.00022 21.7 15.0 0.00032 21.2 0.9 2.3 2 0 0 2 2 2 2 Eukaryotic family of unknown function (DUF1754) PIG-P PF08510.7 CDI87123.1 - 0.14 11.8 1.4 1.8 8.2 0.0 2.1 2 0 0 2 2 2 0 PIG-P DUF4045 PF13254.1 CDI87124.1 - 4.3 6.5 28.2 5.3 6.2 19.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Chorion_2 PF03964.10 CDI87125.1 - 0.029 14.9 1.5 0.029 14.9 1.0 7.7 5 2 1 6 6 6 0 Chorion family 2 DUF1510 PF07423.6 CDI87126.1 - 7.3e-05 22.2 1.9 7.8e-05 22.1 1.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) SpoIIIAH PF12685.2 CDI87126.1 - 0.0031 17.0 0.8 0.004 16.6 0.6 1.0 1 0 0 1 1 1 1 SpoIIIAH-like protein NESP55 PF06390.7 CDI87126.1 - 0.042 13.2 19.8 0.059 12.7 13.7 1.3 1 0 0 1 1 1 0 Neuroendocrine-specific golgi protein P55 (NESP55) NfeD PF01957.13 CDI87126.1 - 0.096 12.8 0.0 0.14 12.3 0.0 1.2 1 0 0 1 1 1 0 NfeD-like C-terminal, partner-binding Ndc1_Nup PF09531.5 CDI87126.1 - 0.13 10.7 0.0 0.18 10.1 0.0 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Zip PF02535.17 CDI87126.1 - 0.14 11.1 0.1 0.17 10.8 0.1 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Ycf1 PF05758.7 CDI87126.1 - 0.17 9.5 4.0 0.19 9.3 2.8 1.1 1 0 0 1 1 1 0 Ycf1 Herpes_DNAp_acc PF04929.7 CDI87126.1 - 0.21 10.5 1.0 0.22 10.4 0.7 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Trypan_PARP PF05887.6 CDI87126.1 - 0.38 10.5 20.3 0.52 10.1 14.1 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) HSP90 PF00183.13 CDI87126.1 - 0.75 8.1 8.5 1 7.6 5.9 1.2 1 0 0 1 1 1 0 Hsp90 protein DDHD PF02862.12 CDI87126.1 - 3.5 7.3 5.1 4 7.1 3.5 1.2 1 0 0 1 1 1 0 DDHD domain CDC45 PF02724.9 CDI87126.1 - 6.8 4.5 18.6 7.9 4.3 12.9 1.0 1 0 0 1 1 1 0 CDC45-like protein TFIIA PF03153.8 CDI87128.1 - 0.18 11.6 5.9 0.23 11.3 4.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit TPP_enzyme_N PF02776.13 CDI87128.1 - 0.21 11.0 9.0 0.41 10.1 6.2 1.4 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain MBOAT PF03062.14 CDI87128.1 - 0.23 10.5 0.9 0.31 10.1 0.6 1.1 1 0 0 1 1 1 0 MBOAT, membrane-bound O-acyltransferase family HdeA PF06411.6 CDI87128.1 - 0.35 10.8 16.7 0.32 10.9 3.0 2.6 3 0 0 3 3 3 0 HdeA/HdeB family FA_desaturase PF00487.19 CDI87128.1 - 3.6 6.9 5.4 5.2 6.4 2.8 1.8 2 0 0 2 2 2 0 Fatty acid desaturase Pex16 PF08610.5 CDI87129.1 - 0.039 12.9 12.4 0.047 12.6 8.6 1.0 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) MRP-S31 PF15433.1 CDI87129.1 - 0.048 13.0 19.1 0.058 12.8 13.3 1.1 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 DUF2052 PF09747.4 CDI87129.1 - 0.052 13.4 17.4 0.061 13.2 12.0 1.1 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) BAF1_ABF1 PF04684.8 CDI87129.1 - 0.11 11.3 26.9 0.13 11.0 18.6 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor CDK2AP PF09806.4 CDI87129.1 - 0.12 12.5 24.6 0.14 12.3 17.1 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein Mu-like_Pro PF10123.4 CDI87129.1 - 0.14 11.6 20.5 0.14 11.5 14.2 1.0 1 0 0 1 1 1 0 Mu-like prophage I protein Lipoprotein_X PF03305.8 CDI87129.1 - 0.34 10.2 8.2 0.35 10.2 5.7 1.1 1 0 0 1 1 1 0 Mycoplasma MG185/MG260 protein Miff PF05644.6 CDI87129.1 - 0.39 10.3 9.0 0.5 9.9 6.2 1.1 1 0 0 1 1 1 0 Mitochondrial and peroxisomal fission factor Mff DUF966 PF06136.8 CDI87129.1 - 0.55 9.6 14.1 0.65 9.3 9.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF966) GerA PF03323.8 CDI87129.1 - 0.82 7.7 4.1 0.91 7.5 2.8 1.1 1 0 0 1 1 1 0 Bacillus/Clostridium GerA spore germination protein Ufd2P_core PF10408.4 CDI87129.1 - 1 7.4 11.8 1.5 6.9 8.2 1.2 1 0 0 1 1 1 0 Ubiquitin elongating factor core DUF4647 PF15504.1 CDI87129.1 - 1.1 8.0 16.9 1.3 7.7 11.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4647) DUF572 PF04502.8 CDI87129.1 - 1.3 8.1 17.0 1.7 7.8 11.8 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) PLRV_ORF5 PF01690.12 CDI87129.1 - 1.3 8.0 13.3 1.5 7.8 9.2 1.0 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein TAF4 PF05236.9 CDI87129.1 - 1.4 8.1 21.3 1.6 7.9 14.7 1.0 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family GAGA_bind PF06217.7 CDI87129.1 - 1.6 8.6 12.7 1.8 8.4 8.8 1.0 1 0 0 1 1 1 0 GAGA binding protein-like family Neur_chan_memb PF02932.11 CDI87129.1 - 1.6 8.5 11.3 1.9 8.2 7.9 1.0 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region VID27 PF08553.5 CDI87129.1 - 1.8 6.7 14.4 1.9 6.5 10.0 1.0 1 0 0 1 1 1 0 VID27 cytoplasmic protein AAA_13 PF13166.1 CDI87129.1 - 1.8 6.9 16.7 2 6.7 11.6 1.0 1 0 0 1 1 1 0 AAA domain hDGE_amylase PF14701.1 CDI87129.1 - 1.9 7.3 9.6 2 7.2 6.7 1.0 1 0 0 1 1 1 0 glucanotransferase domain of human glycogen debranching enzyme FAM176 PF14851.1 CDI87129.1 - 2.3 7.8 6.8 2.9 7.5 4.7 1.2 1 0 0 1 1 1 0 FAM176 family DMRL_synthase PF00885.14 CDI87129.1 - 2.4 7.8 6.9 4 7.0 4.4 1.7 1 1 0 1 1 1 0 6,7-dimethyl-8-ribityllumazine synthase RNA_pol_Rpb1_1 PF04997.7 CDI87129.1 - 2.5 7.2 8.4 2.9 7.0 5.8 1.0 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 1 DUF4661 PF15576.1 CDI87129.1 - 2.8 7.5 7.4 3.3 7.2 5.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4661) Enolase_N PF03952.11 CDI87129.1 - 3.4 7.6 8.6 4.9 7.0 6.0 1.4 1 1 0 1 1 1 0 Enolase, N-terminal domain DDRGK PF09756.4 CDI87129.1 - 3.5 6.9 20.5 4.7 6.5 14.2 1.2 1 0 0 1 1 1 0 DDRGK domain DUF853 PF05872.7 CDI87129.1 - 4 5.6 14.3 4.9 5.3 9.9 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) Cellulose_synt PF03552.9 CDI87129.1 - 4.5 5.4 5.0 4.8 5.3 3.4 1.0 1 0 0 1 1 1 0 Cellulose synthase Hid1 PF12722.2 CDI87129.1 - 5.3 4.5 15.1 5.5 4.5 10.4 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DFF40 PF09230.5 CDI87129.1 - 5.6 6.2 8.6 6.7 6.0 6.0 1.0 1 0 0 1 1 1 0 DNA fragmentation factor 40 kDa Sporozoite_P67 PF05642.6 CDI87129.1 - 5.6 4.6 13.8 6 4.6 9.5 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF724 PF05266.9 CDI87129.1 - 6.6 6.3 17.2 8.5 5.9 11.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Mem_trans PF03547.13 CDI87129.1 - 8.5 4.5 5.7 8.5 4.5 3.9 1.1 1 0 0 1 1 1 0 Membrane transport protein Spore_coat_CotO PF14153.1 CDI87129.1 - 8.8 5.7 20.7 12 5.2 14.4 1.2 1 0 0 1 1 1 0 Spore coat protein CotO DUF2201_N PF13203.1 CDI87129.1 - 9.4 5.3 17.5 11 5.1 12.1 1.0 1 0 0 1 1 1 0 Putative metallopeptidase domain Glyco_hydro_31 PF01055.21 CDI87130.1 - 7.8e-24 84.2 0.0 7.5e-22 77.7 2.2 2.4 1 1 0 2 2 2 1 Glycosyl hydrolases family 31 SprA-related PF12118.3 CDI87130.1 - 6.5e-07 28.9 15.6 6.5e-07 28.9 10.8 2.4 2 1 1 3 3 2 1 SprA-related family Spore_coat_CotO PF14153.1 CDI87130.1 - 0.00019 20.9 47.0 0.00022 20.7 18.0 2.3 2 0 0 2 2 2 2 Spore coat protein CotO AAA_11 PF13086.1 CDI87130.1 - 0.0022 17.6 0.5 0.0022 17.6 0.4 2.2 2 0 0 2 2 2 1 AAA domain Vfa1 PF08432.5 CDI87130.1 - 0.24 11.4 38.4 1.3 8.9 4.5 2.3 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 Zip PF02535.17 CDI87130.1 - 0.24 10.3 22.0 0.52 9.2 0.5 2.2 2 0 0 2 2 2 0 ZIP Zinc transporter TT_ORF1 PF02956.9 CDI87130.1 - 0.63 8.4 19.0 0.45 8.9 6.6 2.1 2 0 0 2 2 2 0 TT viral orf 1 CDC45 PF02724.9 CDI87130.1 - 1.5 6.7 36.6 1.6 6.6 16.8 2.1 2 0 0 2 2 2 0 CDC45-like protein DUF1510 PF07423.6 CDI87130.1 - 1.8 7.9 46.1 1.8 7.8 4.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) LMBR1 PF04791.11 CDI87130.1 - 1.9 6.9 11.9 0.1 11.1 2.1 2.0 2 0 0 2 2 2 0 LMBR1-like membrane protein Med15 PF09606.5 CDI87130.1 - 2.7 6.0 107.1 0.0086 14.3 23.3 2.0 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal Porin_4 PF13609.1 CDI87130.1 - 2.8 7.3 10.4 3.4 7.0 0.1 2.2 2 0 0 2 2 2 0 Gram-negative porin Otopetrin PF03189.8 CDI87130.1 - 5 5.9 15.3 0.029 13.4 1.5 2.1 2 0 0 2 2 2 0 Otopetrin PsaN PF05479.6 CDI87130.1 - 5.1 7.0 11.7 19 5.2 0.1 2.6 2 0 0 2 2 2 0 Photosystem I reaction centre subunit N (PSAN or PSI-N) Chorion_S16 PF05836.7 CDI87130.1 - 6.5 6.7 19.1 0.14 12.0 0.3 2.5 2 0 0 2 2 2 0 Chorion protein S16 Tim54 PF11711.3 CDI87130.1 - 7.5 5.0 31.4 2.5 6.6 12.0 2.2 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 SDA1 PF05285.7 CDI87130.1 - 9 5.4 37.4 2.6 7.2 13.9 2.2 2 0 0 2 2 2 0 SDA1 SOBP PF15279.1 CDI87130.1 - 9.7 6.4 40.0 3.5 7.9 8.6 2.1 2 0 0 2 2 2 0 Sine oculis-binding protein MGS PF02142.17 CDI87131.1 - 8.3e-05 22.4 0.0 0.00025 20.8 0.0 1.8 1 0 0 1 1 1 1 MGS-like domain Rtf2 PF04641.7 CDI87131.1 - 8.3e-05 21.9 6.7 0.0001 21.5 4.6 1.2 1 0 0 1 1 1 1 Rtf2 RING-finger RP-C_C PF11800.3 CDI87131.1 - 0.024 14.3 2.0 0.033 13.8 1.4 1.2 1 0 0 1 1 1 0 Replication protein C C-terminal region SR-25 PF10500.4 CDI87131.1 - 0.027 13.9 29.2 0.04 13.3 20.2 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein TAF1D PF15333.1 CDI87131.1 - 0.033 13.9 14.1 0.041 13.6 9.7 1.2 1 0 0 1 1 1 0 TATA box-binding protein-associated factor 1D Neur_chan_memb PF02932.11 CDI87131.1 - 0.043 13.7 0.7 0.037 13.8 0.5 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region LIM_bind PF01803.11 CDI87131.1 - 0.078 12.0 4.8 0.11 11.5 3.3 1.1 1 0 0 1 1 1 0 LIM-domain binding protein Band_3_cyto PF07565.8 CDI87131.1 - 0.14 11.6 2.6 0.16 11.4 1.8 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain BLVR PF06375.6 CDI87131.1 - 0.25 11.1 29.4 0.51 10.1 20.4 1.4 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) GAGA_bind PF06217.7 CDI87131.1 - 0.3 11.0 17.9 0.39 10.6 12.4 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family OATP PF03137.15 CDI87131.1 - 0.6 8.1 3.3 0.69 7.8 2.3 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family LicD PF04991.8 CDI87131.1 - 0.99 9.4 8.3 1.4 8.9 5.8 1.2 1 0 0 1 1 1 0 LicD family Ndc1_Nup PF09531.5 CDI87131.1 - 1.5 7.1 4.8 1.8 6.8 3.3 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF2413 PF10310.4 CDI87131.1 - 2 7.1 17.6 2.6 6.7 12.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) DUF1168 PF06658.7 CDI87131.1 - 2.5 7.5 34.2 4.8 6.7 23.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) RNA_pol_Rpc4 PF05132.9 CDI87131.1 - 3.6 7.5 15.2 7 6.6 10.5 1.4 1 0 0 1 1 1 0 RNA polymerase III RPC4 HSP90 PF00183.13 CDI87131.1 - 4.8 5.4 15.8 6.8 4.9 11.0 1.2 1 0 0 1 1 1 0 Hsp90 protein DUF106 PF01956.11 CDI87131.1 - 4.8 6.6 7.8 6.6 6.2 5.4 1.2 1 0 0 1 1 1 0 Integral membrane protein DUF106 FLO_LFY PF01698.11 CDI87131.1 - 5 5.8 15.4 6.8 5.4 10.7 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein eIF3_subunit PF08597.5 CDI87131.1 - 5.4 6.5 25.7 8.3 5.8 17.8 1.2 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit AIF_C PF14721.1 CDI87131.1 - 7.3 6.8 10.7 12 6.0 7.4 1.3 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term DUF3807 PF12720.2 CDI87131.1 - 7.3 6.7 20.0 11 6.0 13.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) Peptidase_U57 PF05582.7 CDI87131.1 - 9.6 5.0 11.0 13 4.6 7.6 1.1 1 0 0 1 1 1 0 YabG peptidase U57 DUF2076 PF09849.4 CDI87132.1 - 0.00076 19.6 31.9 0.00076 19.6 22.1 3.0 2 1 1 3 3 3 1 Uncharacterized protein conserved in bacteria (DUF2076) MIP-T3 PF10243.4 CDI87132.1 - 0.095 11.1 78.2 0.031 12.7 28.3 2.1 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 FLO_LFY PF01698.11 CDI87132.1 - 1.6 7.4 57.3 1.4 7.7 19.7 2.3 2 0 0 2 2 2 0 Floricaula / Leafy protein DUF2413 PF10310.4 CDI87132.1 - 1.7 7.4 67.7 1.1 7.9 23.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2413) GAGA_bind PF06217.7 CDI87132.1 - 4.3 7.2 63.0 0.57 10.1 13.5 2.1 2 0 0 2 2 2 0 GAGA binding protein-like family DDHD PF02862.12 CDI87133.1 - 0.05 13.3 9.7 0.057 13.2 6.7 1.1 1 0 0 1 1 1 0 DDHD domain RNA_polI_A34 PF08208.6 CDI87133.1 - 0.079 12.6 26.8 0.13 11.9 18.6 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 GAGA_bind PF06217.7 CDI87133.1 - 6 6.7 16.2 7.5 6.4 11.2 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family DUF1510 PF07423.6 CDI87133.1 - 6.2 6.1 28.8 7.9 5.7 19.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) SNF2_N PF00176.18 CDI87134.1 - 1.1e-17 63.7 0.0 2.1e-15 56.3 0.0 2.4 2 0 0 2 2 2 2 SNF2 family N-terminal domain zf-C4_Topoisom PF01396.14 CDI87134.1 - 3.4e-07 29.6 3.5 3.4e-07 29.6 2.4 1.9 2 0 0 2 2 2 1 Topoisomerase DNA binding C4 zinc finger HNH PF01844.18 CDI87134.1 - 1.9e-05 24.4 0.1 6.8e-05 22.6 0.1 2.0 1 0 0 1 1 1 1 HNH endonuclease DEAD PF00270.24 CDI87134.1 - 0.00014 21.4 0.0 0.0003 20.3 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CDI87134.1 - 0.11 12.3 0.9 0.3 10.9 0.0 2.2 2 0 0 2 2 2 0 Helicase conserved C-terminal domain AAA_22 PF13401.1 CDI87134.1 - 0.12 12.5 0.0 0.45 10.6 0.0 2.0 1 0 0 1 1 1 0 AAA domain Cyclin PF08613.6 CDI87136.1 - 2e-28 99.6 0.0 4.1e-28 98.6 0.0 1.5 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 CDI87136.1 - 2.5e-06 27.0 0.0 2.5e-06 27.0 0.0 3.1 3 0 0 3 3 3 1 Cyclin, N-terminal domain dCMP_cyt_deam_2 PF08211.6 CDI87136.1 - 0.039 13.9 0.9 0.09 12.7 0.0 2.0 2 0 0 2 2 2 0 Cytidine and deoxycytidylate deaminase zinc-binding region VIT1 PF01988.14 CDI87137.1 - 0.0016 18.0 6.0 0.0016 18.0 4.2 4.5 3 1 0 3 3 3 1 VIT family DUF1042 PF06294.6 CDI87138.1 - 9.4e-08 31.7 0.6 1e-05 25.2 0.0 4.4 5 0 0 5 5 5 2 Domain of Unknown Function (DUF1042) SR-25 PF10500.4 CDI87140.1 - 0.0021 17.5 3.2 0.0021 17.5 2.2 11.9 11 1 0 11 11 11 4 Nuclear RNA-splicing-associated protein AAA_23 PF13476.1 CDI87140.1 - 0.003 17.9 3.2 0.003 17.9 2.2 7.3 4 1 0 5 5 5 1 AAA domain FimP PF09766.4 CDI87141.1 - 0.27 10.2 36.9 0.3 10.1 2.5 3.1 3 0 0 3 3 3 0 Fms-interacting protein DUF1053 PF06327.9 CDI87141.1 - 1.2 9.5 16.4 0.54 10.6 0.4 3.2 3 0 0 3 3 3 0 Domain of Unknown Function (DUF1053) SDH_beta PF03315.10 CDI87142.1 - 1.2 9.2 4.2 1.3 9.0 2.9 1.1 1 0 0 1 1 1 0 Serine dehydratase beta chain Ebola_NP PF05505.7 CDI87143.1 - 2 6.4 51.5 0.03 12.3 29.7 2.2 2 0 0 2 2 2 0 Ebola nucleoprotein AAA_23 PF13476.1 CDI87144.1 - 0.00058 20.2 5.0 0.00063 20.1 3.5 1.2 1 0 0 1 1 1 1 AAA domain CAF-1_p150 PF11600.3 CDI87144.1 - 0.0033 16.8 19.2 0.0033 16.8 13.3 2.0 2 0 0 2 2 2 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal SprA-related PF12118.3 CDI87144.1 - 0.0046 16.3 39.5 0.0063 15.8 27.4 1.2 1 0 0 1 1 1 1 SprA-related family UPF0564 PF10595.4 CDI87144.1 - 0.042 12.7 20.3 0.053 12.4 14.1 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0564 DUF605 PF04652.11 CDI87144.1 - 0.079 12.3 35.3 0.096 12.0 24.5 1.0 1 0 0 1 1 1 0 Vta1 like eIF-3_zeta PF05091.7 CDI87144.1 - 0.31 9.6 14.0 0.31 9.6 9.7 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) PAT1 PF09770.4 CDI87144.1 - 0.55 8.4 35.8 0.67 8.1 24.8 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Herpes_UL87 PF03043.9 CDI87144.1 - 0.9 7.8 5.7 0.9 7.8 4.0 1.2 1 0 0 1 1 1 0 Herpesvirus UL87 family MRP-S31 PF15433.1 CDI87144.1 - 1.8 7.9 19.1 0.39 10.0 10.9 1.5 2 0 0 2 2 2 0 Mitochondrial 28S ribosomal protein S31 DUF1764 PF08576.5 CDI87144.1 - 2 9.2 16.0 0.68 10.7 8.1 2.2 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF1764) SR-25 PF10500.4 CDI87144.1 - 3.8 6.9 39.2 0.054 12.9 9.1 2.3 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein BTV_NS2 PF04514.7 CDI87144.1 - 4.6 6.0 11.1 6.4 5.5 7.7 1.2 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 TFIIA PF03153.8 CDI87144.1 - 5.6 6.7 35.5 9.3 6.0 24.6 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Macoilin PF09726.4 CDI87144.1 - 6.8 4.8 24.9 11 4.2 17.3 1.3 1 0 0 1 1 1 0 Transmembrane protein Transket_pyr PF02779.19 CDI87145.1 - 2.4e-42 144.4 0.0 4e-42 143.7 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 CDI87145.1 - 2.3e-37 127.6 0.2 3.9e-37 126.9 0.1 1.4 1 0 0 1 1 1 1 Transketolase, C-terminal domain DUF77 PF01910.12 CDI87145.1 - 0.09 12.4 0.2 0.16 11.6 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function DUF77 CDK2AP PF09806.4 CDI87148.1 - 0.0049 17.1 7.7 0.0049 17.1 5.3 8.6 5 1 0 5 5 5 3 Cyclin-dependent kinase 2-associated protein Ycf1 PF05758.7 CDI87148.1 - 0.76 7.4 8.0 0.049 11.3 0.2 2.5 3 0 0 3 3 3 0 Ycf1 Rrn6 PF10214.4 CDI87149.1 - 0.34 8.9 15.5 0.38 8.7 10.7 1.0 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor PAT1 PF09770.4 CDI87149.1 - 0.42 8.7 25.5 0.45 8.6 17.7 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 nec1 PF10379.4 CDI87151.1 - 0.011 15.0 0.3 0.013 14.7 0.2 1.1 1 0 0 1 1 1 0 Virulence protein nec1 Neur_chan_memb PF02932.11 CDI87151.1 - 0.17 11.7 10.3 0.26 11.1 7.1 1.3 1 1 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region PAXIP1_C PF15364.1 CDI87151.1 - 0.18 11.7 18.9 0.085 12.7 3.2 2.2 2 0 0 2 2 2 0 PAXIP1-associated-protein-1 C term PTIP binding protein FimP PF09766.4 CDI87151.1 - 0.36 9.8 41.7 0.25 10.3 12.5 2.1 2 0 0 2 2 2 0 Fms-interacting protein FAM176 PF14851.1 CDI87151.1 - 1 9.0 12.8 1.4 8.5 0.3 2.1 2 0 0 2 2 2 0 FAM176 family PH_4 PF15404.1 CDI87151.1 - 2.6 7.5 15.6 1.1 8.7 2.7 2.3 2 0 0 2 2 2 0 Pleckstrin homology domain Peroxin-13_N PF04088.8 CDI87151.1 - 2.9 7.8 10.9 6 6.7 2.4 2.3 2 0 0 2 2 2 0 Peroxin 13, N-terminal region Na_trans_assoc PF06512.8 CDI87151.1 - 3.4 7.5 12.3 5.3 6.9 0.7 2.1 2 0 0 2 2 2 0 Sodium ion transport-associated Gti1_Pac2 PF09729.4 CDI87151.1 - 3.7 7.3 13.7 1.8 8.3 0.4 2.2 2 0 0 2 2 2 0 Gti1/Pac2 family DUF572 PF04502.8 CDI87151.1 - 6.7 5.8 24.6 8.9 5.4 17.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) MSP1_C PF07462.6 CDI87151.1 - 6.7 4.9 12.6 8.5 4.6 8.7 1.2 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus RNA_pol_Rpc4 PF05132.9 CDI87151.1 - 8 6.4 19.7 1.7 8.6 1.6 2.3 2 0 0 2 2 2 0 RNA polymerase III RPC4 DUF3381 PF11861.3 CDI87151.1 - 8.6 5.8 23.4 6 6.3 3.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3381) DUF1071 PF06378.6 CDI87151.1 - 9.3 5.3 24.3 0.2 10.7 4.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1071) Ribosomal_L24e PF01246.15 CDI87152.1 - 7e-20 70.6 1.0 7e-20 70.6 0.7 2.5 3 0 0 3 3 3 1 Ribosomal protein L24e PI31_Prot_C PF08577.6 CDI87152.1 - 0.007 16.9 0.4 5 7.8 0.0 2.3 1 1 1 2 2 2 2 PI31 proteasome regulator Med15 PF09606.5 CDI87153.1 - 7e-05 21.2 8.2 7e-05 21.2 5.7 2.6 2 1 0 2 2 2 1 ARC105 or Med15 subunit of Mediator complex non-fungal PAT1 PF09770.4 CDI87153.1 - 0.12 10.5 61.0 0.063 11.5 24.9 2.1 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 Plasmodium_Vir PF05795.6 CDI87153.1 - 3.4 6.7 8.4 3.8 6.5 1.0 2.2 2 0 0 2 2 2 0 Plasmodium vivax Vir protein Peptidase_S64 PF08192.6 CDI87153.1 - 3.9 5.6 24.1 0.033 12.5 6.4 2.1 2 0 0 2 2 2 0 Peptidase family S64 CDC45 PF02724.9 CDI87154.1 - 0.14 10.1 15.4 0.12 10.3 10.7 1.0 1 0 0 1 1 1 0 CDC45-like protein Band_3_cyto PF07565.8 CDI87154.1 - 0.14 11.6 17.8 0.17 11.3 12.4 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain DDHD PF02862.12 CDI87154.1 - 0.22 11.2 14.5 0.25 11.1 10.1 1.3 1 0 0 1 1 1 0 DDHD domain AAA_11 PF13086.1 CDI87154.1 - 0.42 10.1 16.9 0.44 10.0 11.7 1.2 1 0 0 1 1 1 0 AAA domain CKAP2_C PF15297.1 CDI87154.1 - 0.45 9.2 17.6 0.52 9.0 12.2 1.2 1 0 0 1 1 1 0 Cytoskeleton-associated protein 2 C-terminus SPX PF03105.14 CDI87154.1 - 0.48 10.1 16.4 0.45 10.2 11.4 1.1 1 0 0 1 1 1 0 SPX domain DUF2126 PF09899.4 CDI87154.1 - 0.48 8.3 15.9 0.52 8.2 11.0 1.1 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) Draxin PF15550.1 CDI87154.1 - 0.54 9.8 18.1 0.68 9.5 12.5 1.1 1 0 0 1 1 1 0 Draxin DUF4045 PF13254.1 CDI87154.1 - 0.7 9.1 20.9 0.78 8.9 14.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) SAGA-Tad1 PF12767.2 CDI87154.1 - 0.72 9.4 19.6 0.81 9.3 13.6 1.2 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit Hid1 PF12722.2 CDI87154.1 - 0.77 7.3 18.9 0.76 7.3 13.1 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein FAM60A PF15396.1 CDI87154.1 - 0.85 9.3 13.5 0.95 9.1 9.4 1.2 1 0 0 1 1 1 0 Protein Family FAM60A PAT1 PF09770.4 CDI87154.1 - 0.91 7.6 51.2 0.93 7.6 35.5 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 eIF-3_zeta PF05091.7 CDI87154.1 - 0.91 8.0 26.3 1.1 7.8 18.2 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) YjgP_YjgQ PF03739.9 CDI87154.1 - 1 8.0 9.5 1.1 7.8 6.6 1.1 1 0 0 1 1 1 0 Predicted permease YjgP/YjgQ family BTV_NS2 PF04514.7 CDI87154.1 - 1.1 8.1 14.3 1.1 8.1 9.9 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Zip PF02535.17 CDI87154.1 - 1.2 8.0 10.0 1.4 7.8 6.9 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Ofd1_CTDD PF10637.4 CDI87154.1 - 1.3 8.1 12.7 1.4 8.0 8.8 1.1 1 0 0 1 1 1 0 Oxoglutarate and iron-dependent oxygenase degradation C-term Calici_coat_C PF08435.6 CDI87154.1 - 1.3 8.2 11.4 1.2 8.3 7.9 1.1 1 0 0 1 1 1 0 Calicivirus coat protein C-terminal FemAB PF02388.11 CDI87154.1 - 1.8 7.1 19.5 2 7.0 13.5 1.1 1 0 0 1 1 1 0 FemAB family HGTP_anticodon2 PF12745.2 CDI87154.1 - 1.9 7.5 14.8 2.4 7.2 10.3 1.3 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs DUF1510 PF07423.6 CDI87154.1 - 1.9 7.7 21.6 2.6 7.3 15.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) AUX_IAA PF02309.11 CDI87154.1 - 2.4 7.8 17.9 3.2 7.4 12.4 1.3 1 0 0 1 1 1 0 AUX/IAA family DDRGK PF09756.4 CDI87154.1 - 2.8 7.3 29.1 3.6 6.9 20.2 1.2 1 0 0 1 1 1 0 DDRGK domain SRP-alpha_N PF04086.8 CDI87154.1 - 2.8 7.2 22.9 3.3 7.0 15.9 1.0 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Glyco_transf_15 PF01793.11 CDI87154.1 - 3 6.6 17.0 3.8 6.3 11.8 1.2 1 0 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase DUF45 PF01863.12 CDI87154.1 - 3 7.5 13.8 3.6 7.3 9.6 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF45 Plasmodium_Vir PF05795.6 CDI87154.1 - 3.1 6.9 5.6 3.9 6.5 3.9 1.3 1 0 0 1 1 1 0 Plasmodium vivax Vir protein PIH1 PF08190.7 CDI87154.1 - 3.1 7.1 26.0 3.5 6.9 18.0 1.1 1 0 0 1 1 1 0 pre-RNA processing PIH1/Nop17 F-protein PF00469.15 CDI87154.1 - 3.2 7.0 14.2 3.5 6.9 9.9 1.2 1 0 0 1 1 1 0 Negative factor, (F-Protein) or Nef DUF4638 PF15472.1 CDI87154.1 - 3.5 7.1 15.4 3.5 7.1 10.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) PLRV_ORF5 PF01690.12 CDI87154.1 - 3.5 6.6 22.7 3.5 6.6 15.7 1.0 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Na_trans_assoc PF06512.8 CDI87154.1 - 4 7.3 12.4 5.7 6.8 8.6 1.2 1 0 0 1 1 1 0 Sodium ion transport-associated SAPS PF04499.10 CDI87154.1 - 4.5 5.7 17.8 4.6 5.7 12.3 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Tim54 PF11711.3 CDI87154.1 - 4.8 5.6 14.4 5.3 5.5 10.0 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Spore_YhcN_YlaJ PF09580.5 CDI87154.1 - 5.9 6.9 22.3 7.1 6.7 15.4 1.2 1 0 0 1 1 1 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) Cellulose_synt PF03552.9 CDI87154.1 - 5.9 5.0 7.6 5.8 5.0 5.2 1.0 1 0 0 1 1 1 0 Cellulose synthase Raftlin PF15250.1 CDI87154.1 - 7 5.0 18.6 8 4.8 12.9 1.1 1 0 0 1 1 1 0 Raftlin DUF966 PF06136.8 CDI87154.1 - 7.2 5.9 20.1 8.4 5.6 13.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Neur_chan_memb PF02932.11 CDI87154.1 - 7.3 6.4 17.0 7.5 6.3 11.8 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DHHW PF14286.1 CDI87154.1 - 7.5 5.7 17.1 8.4 5.5 11.8 1.1 1 0 0 1 1 1 0 DHHW protein Lin-8 PF03353.10 CDI87154.1 - 7.8 5.6 23.9 7.7 5.7 16.5 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist NPR3 PF03666.8 CDI87154.1 - 8.9 4.7 19.3 10 4.5 13.4 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 vMSA PF00695.14 CDI87154.1 - 9.9 5.2 15.1 11 5.1 10.5 1.1 1 0 0 1 1 1 0 Major surface antigen from hepadnavirus Claudin_2 PF13903.1 CDI87155.1 - 0.023 14.3 0.8 0.023 14.3 0.6 2.3 2 0 0 2 2 1 0 PMP-22/EMP/MP20/Claudin tight junction Esterase PF00756.15 CDI87155.1 - 0.076 12.4 11.6 0.1 12.0 8.0 1.2 1 0 0 1 1 1 0 Putative esterase PRP1_N PF06424.7 CDI87155.1 - 0.1 12.8 11.8 0.15 12.3 8.2 1.4 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal Hid1 PF12722.2 CDI87155.1 - 0.11 10.0 15.5 0.11 10.1 10.8 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Het-C PF07217.6 CDI87155.1 - 0.14 10.2 14.4 0.18 9.9 10.0 1.1 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C SOBP PF15279.1 CDI87155.1 - 0.15 12.3 18.7 0.19 12.1 12.9 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein PAT1 PF09770.4 CDI87155.1 - 0.21 9.7 52.4 0.25 9.5 36.3 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Spore_YhcN_YlaJ PF09580.5 CDI87155.1 - 0.32 11.1 21.3 0.51 10.4 14.8 1.3 1 0 0 1 1 1 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) eIF-3_zeta PF05091.7 CDI87155.1 - 0.53 8.8 19.0 0.62 8.6 13.2 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) BTV_NS2 PF04514.7 CDI87155.1 - 0.81 8.5 13.9 1 8.1 9.7 1.2 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 SPX PF03105.14 CDI87155.1 - 0.81 9.4 18.9 1 9.0 13.1 1.2 1 0 0 1 1 1 0 SPX domain Ycf1 PF05758.7 CDI87155.1 - 1.3 6.6 17.6 1.6 6.3 12.2 1.1 1 0 0 1 1 1 0 Ycf1 DHHW PF14286.1 CDI87155.1 - 1.5 8.0 11.8 2 7.6 8.2 1.3 1 0 0 1 1 1 0 DHHW protein SARG PF15385.1 CDI87155.1 - 1.6 8.0 33.1 1.9 7.7 22.8 1.2 1 1 0 1 1 1 0 Specifically androgen-regulated gene protein Herpes_UL87 PF03043.9 CDI87155.1 - 1.8 6.8 10.6 1.8 6.8 7.3 1.3 1 0 0 1 1 1 0 Herpesvirus UL87 family TFIIA PF03153.8 CDI87155.1 - 2.2 8.1 46.5 3.1 7.6 32.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF1675 PF07897.6 CDI87155.1 - 2.4 7.9 14.8 3.1 7.5 10.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) Neur_chan_memb PF02932.11 CDI87155.1 - 2.7 7.7 15.9 3.8 7.3 11.0 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region SR-25 PF10500.4 CDI87155.1 - 3.4 7.0 24.0 1 8.7 14.4 1.7 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein Asp-B-Hydro_N PF05279.6 CDI87155.1 - 5.1 6.8 14.1 6.8 6.4 9.8 1.3 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region DUF1510 PF07423.6 CDI87155.1 - 5.3 6.3 21.8 8.3 5.7 15.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Med19 PF10278.4 CDI87155.1 - 5.4 6.6 14.4 9.7 5.8 10.0 1.4 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 Peptidase_S64 PF08192.6 CDI87155.1 - 6.4 4.9 20.3 7.7 4.7 14.1 1.0 1 0 0 1 1 1 0 Peptidase family S64 Paramyxo_ncap PF00973.14 CDI87155.1 - 7.1 5.2 15.8 7.9 5.0 10.9 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein DUF755 PF05501.6 CDI87156.1 - 0.0056 16.7 27.5 0.0056 16.7 19.1 5.6 4 2 1 5 5 5 1 Domain of unknown function (DUF755) Dehydrin PF00257.14 CDI87156.1 - 0.018 15.3 8.2 0.018 15.3 5.7 4.2 3 1 0 4 4 4 0 Dehydrin Anticodon_1 PF08264.8 CDI87157.1 - 3.1e-09 36.7 0.1 8.6e-08 32.0 0.0 2.3 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA Pex14_N PF04695.8 CDI87157.1 - 0.0031 17.5 28.3 0.02 14.9 9.9 2.3 2 0 0 2 2 2 2 Peroxisomal membrane anchor protein (Pex14p) conserved region Potyvirid-P3 PF13608.1 CDI87157.1 - 0.0051 15.9 12.2 0.0089 15.1 8.4 1.4 1 0 0 1 1 1 1 Protein P3 of Potyviral polyprotein Striatin PF08232.7 CDI87157.1 - 0.0076 16.5 16.4 0.0076 16.5 11.4 2.2 2 0 0 2 2 2 1 Striatin family Spore_coat_CotO PF14153.1 CDI87157.1 - 0.0083 15.5 14.3 0.0083 15.5 9.9 1.9 2 0 0 2 2 2 1 Spore coat protein CotO FHIPEP PF00771.15 CDI87157.1 - 0.028 12.7 6.9 0.034 12.5 4.7 1.1 1 0 0 1 1 1 0 FHIPEP family Macoilin PF09726.4 CDI87157.1 - 0.076 11.2 32.8 0.1 10.8 22.8 1.1 1 0 0 1 1 1 0 Transmembrane protein Borrelia_P83 PF05262.6 CDI87157.1 - 0.091 11.0 12.7 0.11 10.8 8.8 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF4192 PF13830.1 CDI87157.1 - 0.12 11.9 0.1 0.22 11.1 0.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4192) V_ATPase_I PF01496.14 CDI87157.1 - 0.16 9.8 6.0 0.17 9.7 4.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Peptidase_S15 PF02129.13 CDI87157.1 - 0.21 10.9 7.9 0.27 10.5 5.5 1.2 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) DUF4557 PF15101.1 CDI87157.1 - 0.35 10.6 25.4 0.038 13.8 13.7 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4557) Peptidase_S49_N PF08496.5 CDI87157.1 - 0.45 10.2 16.2 0.73 9.6 11.3 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF3260 PF11658.3 CDI87157.1 - 0.51 8.4 11.6 0.72 7.9 8.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3260) DUF4614 PF15391.1 CDI87157.1 - 0.73 9.5 28.7 0.28 10.9 7.7 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4614) DUF342 PF03961.8 CDI87157.1 - 1.1 7.6 11.3 1.4 7.2 7.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) RP-C_C PF11800.3 CDI87157.1 - 2 8.1 18.5 0.098 12.3 6.1 2.1 2 0 0 2 2 2 0 Replication protein C C-terminal region Lin-8 PF03353.10 CDI87157.1 - 2.3 7.4 23.2 1.5 8.0 11.3 2.0 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist FliP PF00813.15 CDI87157.1 - 2.5 7.7 8.3 4.2 7.0 5.8 1.3 1 0 0 1 1 1 0 FliP family FimP PF09766.4 CDI87157.1 - 3.6 6.5 29.1 0.08 11.9 15.3 1.7 2 0 0 2 2 2 0 Fms-interacting protein DUF4220 PF13968.1 CDI87157.1 - 3.8 6.5 9.0 0.18 10.8 1.6 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4220) DUF106 PF01956.11 CDI87157.1 - 4.2 6.8 12.9 7 6.1 8.7 1.6 1 1 0 1 1 1 0 Integral membrane protein DUF106 AUX_IAA PF02309.11 CDI87157.1 - 5.2 6.7 17.0 1.3 8.6 6.5 2.2 2 0 0 2 2 2 0 AUX/IAA family Gti1_Pac2 PF09729.4 CDI87157.1 - 5.2 6.9 20.4 1.7 8.5 0.9 2.2 2 0 0 2 2 2 0 Gti1/Pac2 family CPSF100_C PF13299.1 CDI87157.1 - 6.8 6.8 18.4 2.4 8.3 7.8 2.1 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal YjgP_YjgQ PF03739.9 CDI87157.1 - 7.4 5.1 7.4 11 4.6 5.1 1.2 1 0 0 1 1 1 0 Predicted permease YjgP/YjgQ family FAM60A PF15396.1 CDI87157.1 - 8.3 6.0 23.2 1.7 8.3 7.3 2.1 2 0 0 2 2 2 0 Protein Family FAM60A Anoctamin PF04547.7 CDI87157.1 - 9.2 4.7 13.3 12 4.3 9.2 1.2 1 0 0 1 1 1 0 Calcium-activated chloride channel Phage_GPO PF05929.6 CDI87157.1 - 9.5 5.3 15.4 13 4.9 10.7 1.2 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase tRNA-synt_1g PF09334.6 CDI87158.1 - 1.5e-05 23.8 0.4 1.5e-05 23.8 0.3 3.0 3 0 0 3 3 3 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 CDI87158.1 - 2.2e-05 22.6 0.0 0.00068 17.7 0.0 3.8 4 0 0 4 4 4 2 tRNA synthetases class I (I, L, M and V) Med15 PF09606.5 CDI87158.1 - 0.0023 16.2 62.6 0.0023 16.2 43.4 4.7 2 1 2 5 5 5 1 ARC105 or Med15 subunit of Mediator complex non-fungal AAA_23 PF13476.1 CDI87158.1 - 0.0098 16.2 9.9 0.0098 16.2 6.8 2.5 2 0 0 2 2 2 1 AAA domain RAP1 PF07218.6 CDI87158.1 - 0.59 8.1 0.0 0.59 8.1 0.0 5.0 4 1 2 6 6 6 0 Rhoptry-associated protein 1 (RAP-1) Fringe PF02434.11 CDI87160.1 - 1.1e-15 57.5 5.0 9e-10 38.1 0.0 3.9 3 1 1 4 4 4 3 Fringe-like SR-25 PF10500.4 CDI87160.1 - 0.29 10.5 12.2 0.61 9.5 8.5 1.5 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF755 PF05501.6 CDI87160.1 - 8.3 6.4 17.9 20 5.2 12.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF755) YjgP_YjgQ PF03739.9 CDI87161.1 - 0.58 8.8 3.9 6.7 5.3 0.5 2.6 2 0 0 2 2 2 0 Predicted permease YjgP/YjgQ family MCM PF00493.18 CDI87163.1 - 2e-125 418.0 0.1 3e-125 417.4 0.0 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 CDI87163.1 - 1.7e-08 34.9 0.1 6.2e-08 33.1 0.0 2.0 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 CDI87163.1 - 1.1e-06 27.9 0.1 5.7e-06 25.6 0.0 2.0 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 CDI87163.1 - 0.0052 16.4 0.0 0.014 14.9 0.0 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 CDI87163.1 - 0.017 14.8 0.0 0.041 13.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) DUF2451 PF10474.4 CDI87163.1 - 0.13 12.0 0.0 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function C-terminus (DUF2451) BAG PF02179.11 CDI87163.1 - 2 8.5 6.1 0.4 10.8 0.2 2.7 3 0 0 3 3 3 0 BAG domain PT PF04886.7 CDI87165.1 - 7e-05 22.0 20.3 7e-05 22.0 14.1 4.6 4 1 1 5 5 5 2 PT repeat Asp_protease_2 PF13650.1 CDI87166.1 - 1.2e-06 28.9 0.0 5.8e-06 26.7 0.0 2.1 1 1 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 CDI87166.1 - 2.7e-06 27.1 0.0 8.9e-06 25.4 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.15 CDI87166.1 - 4.6e-06 26.4 0.0 1.1e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease RVP_2 PF08284.6 CDI87166.1 - 7.9e-06 25.8 0.0 1.6e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.5 CDI87166.1 - 0.078 12.5 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease RVT_1 PF00078.22 CDI87167.1 - 4.2e-14 52.4 0.0 8.3e-14 51.4 0.0 1.5 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 CDI87168.1 - 1e-10 41.7 0.2 3.3e-09 36.8 0.1 2.4 1 1 0 1 1 1 1 Integrase core domain Ribosomal_L14 PF00238.14 CDI87169.1 - 0.00014 21.6 2.9 0.00042 20.0 1.8 2.0 1 1 0 1 1 1 1 Ribosomal protein L14p/L23e SpoU_methylase PF00588.14 CDI87169.1 - 0.046 13.5 0.1 0.075 12.8 0.0 1.3 1 0 0 1 1 1 0 SpoU rRNA Methylase family DUF2052 PF09747.4 CDI87169.1 - 0.72 9.7 27.8 1.1 9.2 19.3 1.3 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) SOBP PF15279.1 CDI87169.1 - 1.2 9.4 25.3 1.6 9.0 17.5 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein CDC45 PF02724.9 CDI87169.1 - 1.6 6.6 18.1 2.5 6.0 12.6 1.3 1 0 0 1 1 1 0 CDC45-like protein DUF775 PF05603.7 CDI87169.1 - 1.7 8.1 33.3 0.043 13.3 13.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF775) CAF-1_p150 PF11600.3 CDI87169.1 - 4.7 6.5 31.5 2.4 7.4 14.8 2.0 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal PAT1 PF09770.4 CDI87169.1 - 7.8 4.6 73.3 9.3 4.3 50.8 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 RR_TM4-6 PF06459.7 CDI87169.1 - 7.8 6.3 24.5 3.6 7.4 10.4 2.1 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Shadoo PF14999.1 CDI87170.1 - 0.018 14.9 5.9 0.64 9.8 0.8 2.2 2 0 0 2 2 2 0 Shadow of prion protein, neuroprotective PAT1 PF09770.4 CDI87170.1 - 0.28 9.3 94.5 0.34 9.1 65.5 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 CAF-1_p150 PF11600.3 CDI87171.1 - 0.00072 18.9 38.5 0.00072 18.9 26.7 3.0 2 1 0 2 2 2 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal Pox_E2-like PF04497.7 CDI87171.1 - 2 6.3 4.1 3.2 5.6 2.8 1.3 1 0 0 1 1 1 0 Poxviridae protein Hid1 PF12722.2 CDI87173.1 - 0.24 9.0 33.0 0.27 8.8 22.9 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein CDC45 PF02724.9 CDI87173.1 - 0.97 7.3 34.3 1.5 6.7 23.7 1.4 1 0 0 1 1 1 0 CDC45-like protein Ycf1 PF05758.7 CDI87173.1 - 5 4.7 31.5 7.2 4.1 21.9 1.4 1 0 0 1 1 1 0 Ycf1 DUF812 PF05667.6 CDI87174.1 - 0.24 9.8 5.1 0.24 9.8 3.2 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF812) SPX PF03105.14 CDI87175.1 - 0.00074 19.3 3.8 0.00074 19.3 2.6 1.6 2 0 0 2 2 2 1 SPX domain DUF1635 PF07795.6 CDI87175.1 - 0.14 11.5 9.3 0.26 10.6 6.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) DUF755 PF05501.6 CDI87175.1 - 0.28 11.2 20.2 0.83 9.7 13.8 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF755) DUF2018 PF09442.5 CDI87175.1 - 0.42 11.2 4.9 2.7 8.6 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF2018) N6_N4_Mtase PF01555.13 CDI87177.1 - 0.032 13.7 0.0 0.11 12.0 0.0 1.8 1 1 0 1 1 1 0 DNA methylase Ycf1 PF05758.7 CDI87177.1 - 0.07 10.8 17.6 0.069 10.8 12.2 1.1 1 0 0 1 1 1 0 Ycf1 Hid1 PF12722.2 CDI87177.1 - 0.1 10.2 15.9 0.094 10.3 11.0 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF2561 PF10812.3 CDI87177.1 - 0.26 10.8 5.1 0.41 10.2 3.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2561) Draxin PF15550.1 CDI87177.1 - 0.36 10.4 12.6 0.41 10.2 8.7 1.2 1 0 0 1 1 1 0 Draxin DUF4045 PF13254.1 CDI87177.1 - 0.57 9.4 15.3 0.69 9.1 10.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) SPX PF03105.14 CDI87177.1 - 0.73 9.5 17.1 0.76 9.5 11.8 1.1 1 0 0 1 1 1 0 SPX domain Herpes_env PF01673.13 CDI87177.1 - 0.84 8.1 13.5 1 7.8 9.4 1.2 1 0 0 1 1 1 0 Herpesvirus putative major envelope glycoprotein LMBR1 PF04791.11 CDI87177.1 - 0.85 8.1 11.5 0.95 7.9 8.0 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein CRT10 PF08728.5 CDI87177.1 - 1.2 7.0 8.7 1.1 7.1 6.0 1.0 1 0 0 1 1 1 0 CRT10 Mem_trans PF03547.13 CDI87177.1 - 1.3 7.2 5.8 1.3 7.2 4.0 1.2 1 0 0 1 1 1 0 Membrane transport protein Plasmodium_Vir PF05795.6 CDI87177.1 - 1.4 8.0 4.7 1.5 7.9 3.2 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein NARP1 PF12569.3 CDI87177.1 - 1.5 7.4 27.3 1.1 7.9 15.8 2.0 2 0 0 2 2 2 0 NMDA receptor-regulated protein 1 HCO3_cotransp PF00955.16 CDI87177.1 - 4 5.9 6.9 5.5 5.5 4.8 1.2 1 0 0 1 1 1 0 HCO3- transporter family Ndc1_Nup PF09531.5 CDI87177.1 - 4.3 5.6 17.6 4.8 5.4 12.2 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DHHW PF14286.1 CDI87177.1 - 5.4 6.2 14.7 7.1 5.8 10.2 1.1 1 0 0 1 1 1 0 DHHW protein Zip PF02535.17 CDI87177.1 - 5.7 5.8 5.5 8.9 5.2 3.8 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter SID-1_RNA_chan PF13965.1 CDI87177.1 - 6.8 4.7 10.8 7.5 4.5 7.5 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 FAM60A PF15396.1 CDI87177.1 - 9.5 5.8 18.8 14 5.3 13.1 1.2 1 0 0 1 1 1 0 Protein Family FAM60A WD40 PF00400.27 CDI87178.1 - 9.7e-12 44.2 0.2 0.00074 19.2 0.0 3.2 3 0 0 3 3 3 2 WD domain, G-beta repeat FimP PF09766.4 CDI87178.1 - 0.017 14.2 16.9 0.023 13.7 11.7 1.1 1 0 0 1 1 1 0 Fms-interacting protein SprA-related PF12118.3 CDI87178.1 - 0.048 12.9 24.0 0.064 12.5 16.7 1.1 1 0 0 1 1 1 0 SprA-related family Baculo_PP31 PF05311.6 CDI87178.1 - 0.074 12.3 10.1 0.1 11.8 7.0 1.1 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) DUF912 PF06024.7 CDI87178.1 - 0.28 11.2 6.6 0.48 10.5 4.6 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF1644 PF07800.7 CDI87178.1 - 0.42 10.4 8.6 0.29 10.9 4.4 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1644) Peroxin-13_N PF04088.8 CDI87178.1 - 0.48 10.3 4.9 0.74 9.7 3.4 1.3 1 0 0 1 1 1 0 Peroxin 13, N-terminal region Suf PF05843.9 CDI87178.1 - 0.49 10.0 14.4 0.7 9.5 10.0 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) TMEM51 PF15345.1 CDI87178.1 - 0.59 9.7 9.7 0.85 9.2 6.7 1.2 1 0 0 1 1 1 0 Transmembrane protein 51 Nucleoside_tran PF01733.13 CDI87178.1 - 0.61 9.2 2.0 0.77 8.8 1.4 1.1 1 0 0 1 1 1 0 Nucleoside transporter FLO_LFY PF01698.11 CDI87178.1 - 1.3 7.7 11.7 1.9 7.2 8.1 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein AIF_C PF14721.1 CDI87178.1 - 1.5 9.0 6.9 2.3 8.4 4.8 1.4 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Neur_chan_memb PF02932.11 CDI87178.1 - 1.7 8.4 4.8 2.2 8.0 3.3 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Med15 PF09606.5 CDI87178.1 - 1.9 6.6 35.7 2.3 6.2 24.8 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal AAA_23 PF13476.1 CDI87178.1 - 1.9 8.7 16.8 2.7 8.2 11.7 1.1 1 0 0 1 1 1 0 AAA domain Peptidase_S49_N PF08496.5 CDI87178.1 - 2.4 7.9 10.2 3.6 7.3 7.1 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Serinc PF03348.10 CDI87178.1 - 2.5 6.7 9.6 3.4 6.2 6.7 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) DDHD PF02862.12 CDI87178.1 - 2.6 7.7 10.7 3.7 7.2 7.4 1.2 1 0 0 1 1 1 0 DDHD domain Pex14_N PF04695.8 CDI87178.1 - 2.7 8.0 16.4 4.3 7.3 11.4 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Conotoxin PF02950.12 CDI87178.1 - 3.7 8.4 6.7 10 6.9 4.6 1.8 1 0 0 1 1 1 0 Conotoxin Ctr PF04145.10 CDI87178.1 - 5.1 7.1 9.6 9 6.3 6.6 1.3 1 0 0 1 1 1 0 Ctr copper transporter family DUF4557 PF15101.1 CDI87178.1 - 8.1 6.2 22.3 12 5.6 15.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) EIIBC-GUT_N PF03612.9 CDI87178.1 - 9 5.8 8.5 14 5.2 5.9 1.2 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus OATP PF03137.15 CDI87178.1 - 9.2 4.1 8.3 16 3.4 5.8 1.3 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family MACPF PF01823.14 CDI87179.1 - 9.6e-23 80.9 0.0 9.6e-23 80.9 0.0 5.0 3 1 0 5 5 5 1 MAC/Perforin domain FHIPEP PF00771.15 CDI87179.1 - 0.024 12.9 9.7 0.0078 14.6 2.7 2.2 2 0 0 2 2 2 0 FHIPEP family DUF4179 PF13786.1 CDI87179.1 - 0.037 14.2 0.3 3.6 7.8 0.0 3.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4179) DUF4175 PF13779.1 CDI87179.1 - 4.4 4.8 51.2 0.29 8.7 24.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4175) DUF2370 PF10176.4 CDI87180.1 - 0.0014 18.0 2.6 0.0014 18.0 1.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2370) DUF4366 PF14283.1 CDI87180.1 - 0.0082 15.5 3.3 0.009 15.4 2.3 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4366) D123 PF07065.9 CDI87180.1 - 0.02 13.9 5.4 0.022 13.8 3.8 1.0 1 0 0 1 1 1 0 D123 FAM176 PF14851.1 CDI87180.1 - 0.021 14.4 3.8 0.023 14.3 2.6 1.2 1 0 0 1 1 1 0 FAM176 family DUF4337 PF14235.1 CDI87180.1 - 0.023 14.5 8.5 0.024 14.4 5.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) PBP1_TM PF14812.1 CDI87180.1 - 0.029 14.6 0.5 0.03 14.6 0.4 1.2 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Kei1 PF08552.6 CDI87180.1 - 0.046 13.3 3.6 0.052 13.2 2.5 1.0 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 Pex14_N PF04695.8 CDI87180.1 - 0.063 13.3 10.4 0.067 13.2 7.2 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region RIC3 PF15361.1 CDI87180.1 - 0.084 13.1 7.1 0.091 12.9 4.9 1.1 1 0 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 UPF0233 PF06781.7 CDI87180.1 - 0.12 11.9 2.6 0.5 10.0 1.8 1.9 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0233) Ctr PF04145.10 CDI87180.1 - 0.14 12.2 3.4 0.17 11.9 2.4 1.0 1 0 0 1 1 1 0 Ctr copper transporter family CoatB PF10389.4 CDI87180.1 - 0.14 12.0 0.2 0.19 11.6 0.1 1.1 1 0 0 1 1 1 0 Bacteriophage coat protein B Adeno_terminal PF02459.10 CDI87180.1 - 0.19 9.8 6.1 0.21 9.7 4.2 1.1 1 0 0 1 1 1 0 Adenoviral DNA terminal protein FemAB PF02388.11 CDI87180.1 - 0.29 9.7 11.1 0.31 9.6 7.7 1.0 1 0 0 1 1 1 0 FemAB family FimP PF09766.4 CDI87180.1 - 0.29 10.1 14.5 0.28 10.2 10.1 1.1 1 0 0 1 1 1 0 Fms-interacting protein Tom22 PF04281.8 CDI87180.1 - 0.37 10.3 6.5 0.46 10.0 4.5 1.3 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 GLYCAM-1 PF05242.6 CDI87180.1 - 0.38 10.6 7.5 0.4 10.5 5.2 1.1 1 0 0 1 1 1 0 Glycosylation-dependent cell adhesion molecule 1 (GlyCAM-1) AIF_C PF14721.1 CDI87180.1 - 0.44 10.7 5.8 0.45 10.7 4.0 1.1 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term DUF4557 PF15101.1 CDI87180.1 - 0.64 9.8 17.9 0.64 9.8 12.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) Gti1_Pac2 PF09729.4 CDI87180.1 - 0.75 9.6 4.9 0.79 9.5 3.4 1.0 1 0 0 1 1 1 0 Gti1/Pac2 family DUF3043 PF11241.3 CDI87180.1 - 0.75 9.3 4.7 0.8 9.2 3.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) Myc_N PF01056.13 CDI87180.1 - 0.76 8.8 6.2 0.8 8.8 4.3 1.0 1 0 0 1 1 1 0 Myc amino-terminal region DUF3537 PF12056.3 CDI87180.1 - 0.8 8.3 3.6 0.87 8.2 2.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3537) Peptidase_S49_N PF08496.5 CDI87180.1 - 0.98 9.1 6.8 1 9.1 4.7 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Pox_Ag35 PF03286.9 CDI87180.1 - 1 8.8 8.6 1.1 8.7 6.0 1.0 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DUF3464 PF11947.3 CDI87180.1 - 1.1 8.6 5.4 1.2 8.6 3.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) DUF4199 PF13858.1 CDI87180.1 - 1.2 9.0 5.7 1.5 8.7 4.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) Zip PF02535.17 CDI87180.1 - 1.2 8.0 4.2 1.3 8.0 2.9 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter CagX PF03524.10 CDI87180.1 - 1.3 8.3 9.3 1.3 8.2 6.4 1.1 1 0 0 1 1 1 0 Conjugal transfer protein Suf PF05843.9 CDI87180.1 - 1.6 8.4 11.8 1.6 8.4 8.2 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) V_ATPase_I PF01496.14 CDI87180.1 - 2.1 6.0 5.6 2.2 6.0 3.9 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family GAGA_bind PF06217.7 CDI87180.1 - 2.3 8.0 8.0 2.4 8.0 5.6 1.0 1 0 0 1 1 1 0 GAGA binding protein-like family UPF0560 PF10577.4 CDI87180.1 - 2.4 6.2 17.9 2.4 6.3 12.4 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 BTV_NS2 PF04514.7 CDI87180.1 - 2.5 6.8 8.5 2.7 6.8 5.9 1.0 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 EIIBC-GUT_N PF03612.9 CDI87180.1 - 2.5 7.6 7.9 2.7 7.5 5.5 1.1 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Neur_chan_memb PF02932.11 CDI87180.1 - 2.7 7.8 5.1 2.8 7.7 3.5 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Serinc PF03348.10 CDI87180.1 - 2.7 6.5 8.6 2.6 6.6 6.0 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) DUF1764 PF08576.5 CDI87180.1 - 2.8 8.7 11.9 3 8.6 8.2 1.1 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) DHHW PF14286.1 CDI87180.1 - 3.4 6.9 8.3 3.5 6.8 5.8 1.0 1 0 0 1 1 1 0 DHHW protein DUF912 PF06024.7 CDI87180.1 - 3.4 7.7 7.1 7.8 6.6 4.9 1.7 1 1 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) TFIIA PF03153.8 CDI87180.1 - 3.9 7.2 19.9 4 7.2 13.8 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SeqA PF03925.8 CDI87180.1 - 4 7.1 9.2 4.1 7.0 6.4 1.0 1 0 0 1 1 1 0 SeqA protein SID-1_RNA_chan PF13965.1 CDI87180.1 - 4.2 5.4 6.5 4.1 5.4 4.5 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DUF2126 PF09899.4 CDI87180.1 - 4.3 5.2 7.8 4.3 5.2 5.4 1.0 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) DUF607 PF04678.8 CDI87180.1 - 4.6 7.1 6.8 5.2 6.9 4.7 1.1 1 0 0 1 1 1 0 Protein of unknown function, DUF607 Fmp27 PF10344.4 CDI87180.1 - 4.8 4.7 6.5 4.5 4.8 4.5 1.0 1 0 0 1 1 1 0 Mitochondrial protein from FMP27 Tim54 PF11711.3 CDI87180.1 - 5 5.6 9.4 5.2 5.5 6.5 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 OATP PF03137.15 CDI87180.1 - 7 4.5 8.3 7 4.5 5.7 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Bap31 PF05529.7 CDI87180.1 - 7.2 6.0 8.7 7.7 5.9 6.0 1.2 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like DUF688 PF05097.7 CDI87180.1 - 8.6 5.1 9.7 9.1 5.0 6.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF688) G-alpha PF00503.15 CDI87180.1 - 8.9 4.8 10.3 9 4.8 7.2 1.0 1 0 0 1 1 1 0 G-protein alpha subunit ARF7EP_C PF14949.1 CDI87180.1 - 9.2 6.7 9.1 10 6.6 6.3 1.1 1 0 0 1 1 1 0 ARF7 effector protein C-terminus CPSF100_C PF13299.1 CDI87180.1 - 9.3 6.4 9.1 9.5 6.3 6.3 1.1 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Glyco_transf_15 PF01793.11 CDI87180.1 - 9.5 5.0 9.4 9.8 5.0 6.5 1.0 1 0 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase DUF755 PF05501.6 CDI87181.1 - 0.014 15.4 22.8 0.014 15.4 15.8 10.2 5 2 1 6 6 6 0 Domain of unknown function (DUF755) Helicase_C PF00271.26 CDI87182.1 - 0.0077 16.0 0.0 0.022 14.6 0.0 1.7 1 1 0 1 1 1 1 Helicase conserved C-terminal domain DUF4349 PF14257.1 CDI87182.1 - 0.28 10.3 4.5 0.41 9.8 3.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) DHHA1 PF02272.14 CDI87182.1 - 1.1 8.9 9.2 2.6 7.8 6.4 1.7 1 0 0 1 1 1 0 DHHA1 domain TMEM171 PF15471.1 CDI87182.1 - 1.4 7.6 5.6 2.9 6.5 0.9 2.1 2 0 0 2 2 2 0 Transmembrane protein family 171 Med3 PF11593.3 CDI87182.1 - 1.7 7.7 7.2 2 7.5 5.0 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal M_domain PF12938.2 CDI87182.1 - 3 7.5 6.9 4.9 6.8 4.8 1.3 1 0 0 1 1 1 0 M domain of GW182 SR-25 PF10500.4 CDI87182.1 - 9.6 5.5 14.5 16 4.8 10.0 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Med15 PF09606.5 CDI87183.1 - 0.00077 17.8 23.8 0.00095 17.5 16.5 1.3 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal DUF2722 PF10846.3 CDI87183.1 - 0.0048 15.9 4.0 0.015 14.3 0.4 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2722) Guanylin PF02058.10 CDI87183.1 - 0.04 13.9 1.1 0.04 13.9 0.7 1.9 2 0 0 2 2 2 0 Guanylin precursor DUF4557 PF15101.1 CDI87183.1 - 8.5 6.1 11.7 14 5.4 3.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4557) Ashwin PF15323.1 CDI87185.1 - 0.088 12.8 20.4 0.11 12.4 14.1 1.2 1 0 0 1 1 1 0 Developmental protein SprA-related PF12118.3 CDI87185.1 - 0.43 9.8 31.1 0.59 9.4 21.6 1.2 1 0 0 1 1 1 0 SprA-related family DUF605 PF04652.11 CDI87185.1 - 0.74 9.1 22.2 0.89 8.8 15.4 1.1 1 0 0 1 1 1 0 Vta1 like DUF566 PF04484.7 CDI87185.1 - 0.75 9.2 19.1 0.83 9.0 13.3 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF566) SSP160 PF06933.6 CDI87185.1 - 1.6 6.6 21.6 1.7 6.5 15.0 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Suc_Fer-like PF06999.7 CDI87185.1 - 1.7 8.6 7.9 2.2 8.2 5.5 1.2 1 0 0 1 1 1 0 Sucrase/ferredoxin-like ETRAMP PF09716.5 CDI87185.1 - 2.3 8.2 15.7 4.7e+02 0.8 10.9 2.9 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) Presenilin PF01080.12 CDI87185.1 - 6.8 5.4 11.5 8.8 5.0 7.9 1.3 1 0 0 1 1 1 0 Presenilin MLANA PF14991.1 CDI87185.1 - 8.6 6.4 6.1 2 8.4 0.2 2.4 2 1 0 2 2 2 0 Protein melan-A Cwf_Cwc_15 PF04889.7 CDI87185.1 - 8.7 5.9 19.8 1.2 8.7 4.7 2.2 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Hid1 PF12722.2 CDI87186.1 - 0.048 11.3 28.5 0.054 11.1 19.8 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF1180 PF06679.7 CDI87186.1 - 0.18 11.6 1.2 0.37 10.6 0.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Ycf1 PF05758.7 CDI87186.1 - 0.21 9.2 22.8 0.22 9.2 15.8 1.2 1 0 0 1 1 1 0 Ycf1 HemX PF04375.9 CDI87186.1 - 0.35 9.4 50.2 0.46 9.0 34.8 1.1 1 0 0 1 1 1 0 HemX Ribosomal_60s PF00428.14 CDI87186.1 - 0.7 10.3 8.3 1.3 9.4 5.8 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein AMP-binding PF00501.23 CDI87186.1 - 0.75 8.1 3.9 1.1 7.6 2.7 1.2 1 0 0 1 1 1 0 AMP-binding enzyme TFIIA PF03153.8 CDI87186.1 - 2.8 7.7 63.4 3.4 7.4 43.9 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PAT1 PF09770.4 CDI87186.1 - 4.5 5.3 79.6 5.6 5.0 55.2 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 GAGA_bind PF06217.7 CDI87186.1 - 4.8 7.0 30.6 5.9 6.7 21.2 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family SAPS PF04499.10 CDI87186.1 - 4.9 5.6 24.7 7.1 5.1 17.1 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein PCEMA1 PF07418.6 CDI87186.1 - 5.6 6.2 14.4 7.2 5.8 10.0 1.2 1 0 0 1 1 1 0 Acidic phosphoprotein precursor PCEMA1 DHHW PF14286.1 CDI87186.1 - 7.7 5.7 21.0 12 5.1 14.5 1.3 1 0 0 1 1 1 0 DHHW protein GPCR_chapero_1 PF11904.3 CDI87186.1 - 8.8 5.3 22.4 12 4.9 15.5 1.2 1 0 0 1 1 1 0 GPCR-chaperone CAF-1_p150 PF11600.3 CDI87187.1 - 0.0025 17.2 27.9 0.0025 17.2 19.4 6.8 3 1 3 6 6 6 3 Chromatin assembly factor 1 complex p150 subunit, N-terminal Sec16 PF12932.2 CDI87189.1 - 0.0032 17.4 0.1 0.0032 17.4 0.0 2.5 2 1 1 3 3 3 1 Vesicle coat trafficking protein Sec16 mid-region Sporozoite_P67 PF05642.6 CDI87189.1 - 0.014 13.2 27.7 0.026 12.4 13.9 2.2 2 0 0 2 2 2 0 Sporozoite P67 surface antigen BPL_N PF09825.4 CDI87189.1 - 0.35 9.6 5.1 0.71 8.5 3.5 1.4 1 0 0 1 1 1 0 Biotin-protein ligase, N terminal Bac_GDH PF05088.7 CDI87190.1 - 0.78 7.0 32.8 0.88 6.8 22.8 1.1 1 0 0 1 1 1 0 Bacterial NAD-glutamate dehydrogenase Ycf1 PF05758.7 CDI87191.1 - 0.01 13.5 4.3 0.013 13.2 3.0 1.1 1 0 0 1 1 1 0 Ycf1 SAPS PF04499.10 CDI87191.1 - 0.025 13.2 4.8 0.028 13.0 3.3 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein COPI_C PF06957.6 CDI87191.1 - 0.094 11.2 1.2 0.14 10.6 0.8 1.2 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus Nop25 PF09805.4 CDI87191.1 - 0.23 11.5 14.2 0.13 12.2 5.7 2.1 2 0 0 2 2 2 0 Nucleolar protein 12 (25kDa) Med15 PF09606.5 CDI87191.1 - 0.71 7.9 65.0 0.84 7.7 45.1 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal GPCR_chapero_1 PF11904.3 CDI87191.1 - 0.74 8.8 11.6 0.37 9.8 5.5 1.9 2 0 0 2 2 2 0 GPCR-chaperone Spore_coat_CotO PF14153.1 CDI87191.1 - 0.98 8.8 19.0 0.22 10.9 6.8 2.1 2 0 0 2 2 2 0 Spore coat protein CotO DUF2052 PF09747.4 CDI87191.1 - 1.6 8.6 18.2 0.6 10.0 8.2 2.1 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) CDK2AP PF09806.4 CDI87191.1 - 2.5 8.2 17.4 4.2 7.5 5.0 2.4 2 0 0 2 2 2 0 Cyclin-dependent kinase 2-associated protein Afi1 PF07792.7 CDI87191.1 - 3.4 7.6 11.4 4.8 7.1 5.1 2.1 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking AUX_IAA PF02309.11 CDI87191.1 - 5.5 6.6 12.2 11 5.6 0.1 2.3 2 0 0 2 2 2 0 AUX/IAA family FLO_LFY PF01698.11 CDI87191.1 - 6.1 5.5 10.7 6.6 5.4 5.0 2.0 2 0 0 2 2 2 0 Floricaula / Leafy protein DUF2370 PF10176.4 CDI87191.1 - 6.4 6.0 18.1 0.45 9.8 6.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2370) Tim54 PF11711.3 CDI87191.1 - 9.1 4.7 12.5 15 4.0 5.0 2.1 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 PP2C PF00481.16 CDI87192.1 - 3.6e-19 69.1 0.0 3.6e-19 69.1 0.0 2.5 2 1 0 2 2 2 1 Protein phosphatase 2C SGT1 PF07093.6 CDI87192.1 - 0.00012 20.6 25.9 0.00018 20.0 17.9 1.3 1 0 0 1 1 1 1 SGT1 protein SpoIIE PF07228.7 CDI87192.1 - 0.0027 17.4 0.1 0.0027 17.4 0.1 2.3 3 0 0 3 3 3 1 Stage II sporulation protein E (SpoIIE) Metallophos PF00149.23 CDI87193.1 - 2.3e-05 23.8 0.3 0.00012 21.5 0.2 1.9 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase RVT_1 PF00078.22 CDI87194.1 - 1.9e-15 56.8 0.0 3.3e-15 56.0 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.1 CDI87194.1 - 1.6e-10 41.3 0.0 3.1e-10 40.3 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 CDI87194.1 - 3.3e-08 33.2 0.0 8.7e-08 31.8 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.15 CDI87194.1 - 9.5e-06 25.4 0.0 2.2e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease RVP_2 PF08284.6 CDI87194.1 - 6.9e-05 22.7 0.0 0.00016 21.6 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.5 CDI87194.1 - 0.0037 16.8 0.0 0.0078 15.7 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease DUF1758 PF05585.7 CDI87194.1 - 0.023 14.2 0.0 0.05 13.1 0.0 1.5 1 0 0 1 1 1 0 Putative peptidase (DUF1758) DUF836 PF05768.9 CDI87195.1 - 0.07 13.3 0.0 0.12 12.6 0.0 1.5 1 0 0 1 1 1 0 Glutaredoxin-like domain (DUF836) She9_MDM33 PF05546.6 CDI87196.1 - 0.028 13.9 3.4 0.051 13.1 2.4 1.3 1 0 0 1 1 1 0 She9 / Mdm33 family MCPsignal PF00015.16 CDI87196.1 - 0.091 12.2 4.4 0.13 11.7 1.9 2.1 2 0 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Fib_alpha PF08702.5 CDI87196.1 - 3.4 7.7 7.6 2.3 8.3 1.6 2.4 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family IncA PF04156.9 CDI87197.1 - 0.00029 20.4 1.3 2.2 7.8 0.0 3.9 3 1 0 3 3 3 2 IncA protein DivIVA PF05103.8 CDI87197.1 - 6.4 6.8 6.2 24 4.9 0.1 3.4 3 0 0 3 3 3 0 DivIVA protein Tape_meas_lam_C PF09718.5 CDI87198.1 - 1.2 9.1 5.2 11 6.0 0.0 3.9 4 0 0 4 4 4 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) GTPase_Cys_C PF12631.2 CDI87198.1 - 2.5 8.5 5.3 19 5.7 0.2 3.9 3 1 1 4 4 4 0 Catalytic cysteine-containing C-terminus of GTPase, MnmE MFS_1 PF07690.11 CDI87199.1 - 1.3e-12 47.1 20.6 1.3e-12 47.1 14.3 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily ERGIC_N PF13850.1 CDI87199.1 - 0.046 13.6 0.3 0.17 11.8 0.2 1.9 1 0 0 1 1 1 0 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Med15 PF09606.5 CDI87201.1 - 2.4 6.2 80.6 1.1 7.3 9.1 2.1 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal OmpH PF03938.9 CDI87201.1 - 3.1 7.7 63.8 5.2 6.9 32.6 2.3 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) MRP-S31 PF15433.1 CDI87201.1 - 3.4 7.0 32.9 0.62 9.4 14.7 2.2 2 0 0 2 2 2 0 Mitochondrial 28S ribosomal protein S31 Ycf1 PF05758.7 CDI87201.1 - 4.8 4.7 29.3 3.5 5.2 0.4 2.0 2 0 0 2 2 2 0 Ycf1 DUF1314 PF07013.6 CDI87201.1 - 5.8 6.2 7.2 1.2 8.4 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1314) FimP PF09766.4 CDI87202.1 - 0.25 10.3 44.3 0.087 11.8 14.9 2.1 2 0 0 2 2 2 0 Fms-interacting protein CAF-1_p150 PF11600.3 CDI87202.1 - 0.41 9.9 33.8 0.045 13.1 12.7 2.0 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DDRGK PF09756.4 CDI87202.1 - 2.1 7.6 31.1 0.75 9.1 2.4 2.1 2 0 0 2 2 2 0 DDRGK domain Hamartin PF04388.7 CDI87202.1 - 5.7 5.4 30.1 6.5 5.3 20.9 1.0 1 0 0 1 1 1 0 Hamartin protein Myf5 PF12232.3 CDI87202.1 - 5.8 7.5 13.5 0.96 10.1 0.8 2.7 2 1 0 2 2 2 0 Myogenic determination factor 5 Paf1 PF03985.8 CDI87202.1 - 8.1 5.0 26.4 0.51 9.0 8.8 2.1 2 0 0 2 2 2 0 Paf1 THRAP3_BCLAF1 PF15440.1 CDI87203.1 - 6.8e-07 28.3 35.4 8e-07 28.1 24.5 1.0 1 0 0 1 1 1 1 THRAP3/BCLAF1 family PAT1 PF09770.4 CDI87203.1 - 0.017 13.4 37.3 0.019 13.2 25.9 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SAGA-Tad1 PF12767.2 CDI87203.1 - 0.019 14.6 25.3 0.023 14.3 17.5 1.2 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit DUF1777 PF08648.7 CDI87203.1 - 0.079 12.6 26.7 0.11 12.2 18.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) Ycf1 PF05758.7 CDI87203.1 - 0.092 10.4 14.9 0.095 10.4 10.3 1.1 1 0 0 1 1 1 0 Ycf1 SDH_alpha PF03313.10 CDI87203.1 - 0.29 10.1 34.1 0.43 9.5 23.6 1.2 1 0 0 1 1 1 0 Serine dehydratase alpha chain SOBP PF15279.1 CDI87203.1 - 0.3 11.4 33.7 0.34 11.2 23.4 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein DDRGK PF09756.4 CDI87203.1 - 0.31 10.4 23.1 0.45 9.9 16.0 1.2 1 0 0 1 1 1 0 DDRGK domain CAF-1_p150 PF11600.3 CDI87203.1 - 0.31 10.3 40.9 0.49 9.7 28.4 1.3 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal LMBR1 PF04791.11 CDI87203.1 - 0.39 9.2 12.0 0.44 9.0 8.3 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Utp14 PF04615.8 CDI87203.1 - 0.49 8.5 36.8 0.57 8.2 25.5 1.0 1 0 0 1 1 1 0 Utp14 protein Asp-B-Hydro_N PF05279.6 CDI87203.1 - 1.7 8.4 14.9 2 8.2 10.3 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Cellulose_synt PF03552.9 CDI87203.1 - 4.1 5.5 11.6 4.9 5.3 8.0 1.1 1 0 0 1 1 1 0 Cellulose synthase Peptidase_S49_N PF08496.5 CDI87203.1 - 4.2 7.1 17.2 8.7 6.1 11.9 1.6 1 0 0 1 1 1 0 Peptidase family S49 N-terminal AAA_23 PF13476.1 CDI87203.1 - 4.5 7.5 23.5 6.2 7.0 16.3 1.1 1 0 0 1 1 1 0 AAA domain eIF-3_zeta PF05091.7 CDI87203.1 - 4.8 5.6 27.0 5.6 5.4 18.7 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Hid1 PF12722.2 CDI87203.1 - 5.7 4.4 34.7 6.2 4.3 24.0 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein CytochromB561_N PF09786.4 CDI87203.1 - 6.2 5.1 31.4 7 4.9 21.8 1.2 1 0 0 1 1 1 0 Cytochrome B561, N terminal PLRV_ORF5 PF01690.12 CDI87203.1 - 6.5 5.7 33.5 8.3 5.4 23.2 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein DUF4220 PF13968.1 CDI87203.1 - 8.3 5.4 13.7 12 4.9 9.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4220) Glyco_transf_6 PF03414.8 CDI87203.1 - 8.6 4.7 10.6 12 4.2 7.3 1.1 1 0 0 1 1 1 0 Glycosyltransferase family 6 RskA PF10099.4 CDI87204.1 - 0.0013 18.5 6.0 0.0016 18.1 4.2 1.2 1 0 0 1 1 1 1 Anti-sigma-K factor rskA DUF755 PF05501.6 CDI87204.1 - 0.002 18.1 22.0 0.0029 17.6 15.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF755) Med15 PF09606.5 CDI87204.1 - 0.02 13.0 18.3 0.023 12.9 12.7 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF3801 PF12687.2 CDI87204.1 - 0.026 14.0 9.2 0.03 13.9 6.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3801) CCDC71L PF15374.1 CDI87204.1 - 0.11 11.8 12.6 0.12 11.6 8.7 1.0 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 71L Plasmodium_Vir PF05795.6 CDI87204.1 - 0.17 11.0 7.9 0.18 10.9 5.4 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein DUF3373 PF11853.3 CDI87204.1 - 0.19 10.2 6.4 0.19 10.2 4.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) U79_P34 PF03064.11 CDI87204.1 - 0.21 11.0 13.5 0.25 10.8 9.3 1.0 1 0 0 1 1 1 0 HSV U79 / HCMV P34 DUF4638 PF15472.1 CDI87204.1 - 0.25 10.8 9.3 0.26 10.8 6.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) DDRGK PF09756.4 CDI87204.1 - 0.39 10.0 13.9 0.44 9.9 9.7 1.2 1 0 0 1 1 1 0 DDRGK domain DUF2151 PF10221.4 CDI87204.1 - 0.53 8.3 8.4 0.57 8.3 5.8 1.0 1 0 0 1 1 1 0 Cell cycle and development regulator K_channel_TID PF07941.6 CDI87204.1 - 0.59 10.4 13.7 1.3 9.2 9.5 1.6 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain TFIIA PF03153.8 CDI87204.1 - 0.74 9.6 21.1 0.97 9.2 14.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF3450 PF11932.3 CDI87204.1 - 0.75 9.0 15.3 0.95 8.6 10.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF808 PF05661.7 CDI87204.1 - 0.86 8.3 5.6 1.1 7.9 3.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF808) Med19 PF10278.4 CDI87204.1 - 0.88 9.2 6.9 1.1 8.9 4.8 1.2 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 MACPF PF01823.14 CDI87204.1 - 0.89 9.2 7.3 1.1 8.8 5.0 1.1 1 0 0 1 1 1 0 MAC/Perforin domain CDK5_activator PF03261.10 CDI87204.1 - 0.96 8.7 11.0 1 8.6 7.6 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein FLO_LFY PF01698.11 CDI87204.1 - 0.97 8.2 13.2 1.1 7.9 9.1 1.2 1 0 0 1 1 1 0 Floricaula / Leafy protein DUF3807 PF12720.2 CDI87204.1 - 1.1 9.3 18.2 1.4 9.1 12.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) DUF2052 PF09747.4 CDI87204.1 - 1.2 8.9 15.7 1.4 8.7 10.9 1.1 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) VIT1 PF01988.14 CDI87204.1 - 1.4 8.3 4.8 1.5 8.2 3.3 1.2 1 0 0 1 1 1 0 VIT family Apt1 PF10351.4 CDI87204.1 - 1.4 7.6 10.7 1.5 7.6 7.4 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF4603 PF15376.1 CDI87204.1 - 1.4 5.9 14.3 1.5 5.9 9.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) FHIPEP PF00771.15 CDI87204.1 - 1.4 7.1 4.7 1.4 7.1 3.3 1.1 1 0 0 1 1 1 0 FHIPEP family SAGA-Tad1 PF12767.2 CDI87204.1 - 1.5 8.3 12.9 1.8 8.1 8.9 1.1 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit MARCKS PF02063.12 CDI87204.1 - 1.6 8.5 33.0 1.9 8.2 22.9 1.0 1 0 0 1 1 1 0 MARCKS family G-7-MTase PF12803.2 CDI87204.1 - 1.6 7.8 6.7 1.8 7.5 4.6 1.0 1 0 0 1 1 1 0 mRNA (guanine-7-)methyltransferase (G-7-MTase) Vfa1 PF08432.5 CDI87204.1 - 1.7 8.6 17.8 1.9 8.4 12.3 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Hid1 PF12722.2 CDI87204.1 - 1.7 6.2 14.9 1.8 6.1 10.3 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF2215 PF10225.4 CDI87204.1 - 1.8 7.9 5.5 2.2 7.6 3.8 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) DUF4367 PF14285.1 CDI87204.1 - 1.9 7.7 7.1 1 8.6 3.3 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4367) DUF4557 PF15101.1 CDI87204.1 - 2 8.1 13.4 2.5 7.9 9.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) DUF4175 PF13779.1 CDI87204.1 - 2.1 5.9 21.3 2.3 5.8 14.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Asp-B-Hydro_N PF05279.6 CDI87204.1 - 2.1 8.1 13.8 2.3 7.9 9.6 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region RRP14 PF15459.1 CDI87204.1 - 2.1 8.5 8.7 5.5 7.1 6.0 1.8 1 0 0 1 1 1 0 60S ribosome biogenesis protein Rrp14 FAM176 PF14851.1 CDI87204.1 - 2.3 7.8 10.8 3.2 7.4 7.5 1.2 1 0 0 1 1 1 0 FAM176 family FAM60A PF15396.1 CDI87204.1 - 2.4 7.8 11.2 2.7 7.7 7.8 1.1 1 0 0 1 1 1 0 Protein Family FAM60A DUF1510 PF07423.6 CDI87204.1 - 2.7 7.3 18.6 3.5 6.9 12.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) CDC27 PF09507.5 CDI87204.1 - 3.1 6.9 21.1 3.7 6.6 14.6 1.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 AUX_IAA PF02309.11 CDI87204.1 - 3.7 7.2 13.4 4.7 6.8 9.3 1.1 1 0 0 1 1 1 0 AUX/IAA family Serinc PF03348.10 CDI87204.1 - 3.9 6.0 9.3 4.3 5.9 6.5 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) Ycf1 PF05758.7 CDI87204.1 - 4.5 4.8 13.0 4.8 4.7 9.0 1.0 1 0 0 1 1 1 0 Ycf1 GAGA_bind PF06217.7 CDI87204.1 - 4.6 7.1 12.1 5.3 6.9 8.4 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family DUF2217 PF10265.4 CDI87204.1 - 5.2 5.7 8.9 6 5.5 6.1 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) BTV_NS2 PF04514.7 CDI87204.1 - 5.3 5.8 12.4 5.5 5.7 8.6 1.0 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 CDC45 PF02724.9 CDI87204.1 - 5.7 4.8 17.4 6.2 4.7 12.0 1.0 1 0 0 1 1 1 0 CDC45-like protein Ndc1_Nup PF09531.5 CDI87204.1 - 6 5.1 15.1 7.2 4.9 10.5 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Herpes_pp85 PF04637.7 CDI87204.1 - 6.2 4.9 10.1 7.2 4.7 7.0 1.0 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) PMSI1 PF15322.1 CDI87204.1 - 6.5 5.7 15.7 7.9 5.4 10.9 1.1 1 0 0 1 1 1 0 Protein missing in infertile sperm 1, putative Neur_chan_memb PF02932.11 CDI87204.1 - 6.6 6.5 8.3 7.3 6.4 5.8 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region PIH1 PF08190.7 CDI87204.1 - 6.9 6.0 15.1 7.9 5.8 10.5 1.1 1 0 0 1 1 1 0 pre-RNA processing PIH1/Nop17 DHHW PF14286.1 CDI87204.1 - 7.3 5.8 11.3 9.1 5.4 7.9 1.3 1 0 0 1 1 1 0 DHHW protein TRAP_alpha PF03896.11 CDI87204.1 - 8.1 5.3 9.0 8.9 5.2 6.3 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit RAB3GAP2_N PF14655.1 CDI87204.1 - 8.2 5.3 10.8 1.5 7.7 5.2 1.4 1 1 1 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Glyco_transf_15 PF01793.11 CDI87204.1 - 8.9 5.1 7.9 10 4.9 5.4 1.2 1 0 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase DivIC PF04977.10 CDI87204.1 - 9.1 5.8 11.8 15 5.1 8.2 1.3 1 0 0 1 1 1 0 Septum formation initiator Macoilin PF09726.4 CDI87204.1 - 9.9 4.3 16.4 13 3.9 11.4 1.2 1 0 0 1 1 1 0 Transmembrane protein Ndc1_Nup PF09531.5 CDI87205.1 - 0.23 9.8 6.7 0.3 9.4 4.6 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup TMEM171 PF15471.1 CDI87205.1 - 0.54 8.9 3.5 0.24 10.1 0.2 1.8 1 1 0 2 2 2 0 Transmembrane protein family 171 Calici_coat PF00915.15 CDI87205.1 - 0.69 8.7 5.2 1.2 8.0 1.2 2.0 2 0 0 2 2 2 0 Calicivirus coat protein DUF3121 PF11319.3 CDI87205.1 - 1.9 7.9 11.2 4.3 6.7 0.2 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3121) FAM60A PF15396.1 CDI87205.1 - 1.9 8.1 7.1 3.3 7.4 0.7 2.1 2 0 0 2 2 2 0 Protein Family FAM60A FYDLN_acid PF09538.5 CDI87206.1 - 2.8 8.5 10.0 3.5 8.2 7.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) DUF1510 PF07423.6 CDI87206.1 - 7 5.9 22.5 7.9 5.7 15.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Gti1_Pac2 PF09729.4 CDI87206.1 - 7.8 6.3 17.1 9 6.1 11.8 1.1 1 0 0 1 1 1 0 Gti1/Pac2 family DUF4175 PF13779.1 CDI87206.1 - 8.9 3.8 61.5 9.6 3.7 42.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Pox_Ag35 PF03286.9 CDI87206.1 - 9.9 5.6 15.1 11 5.4 10.4 1.0 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DHQS PF01959.11 CDI87207.1 - 0.061 12.0 0.6 0.12 11.0 0.4 1.4 1 0 0 1 1 1 0 3-dehydroquinate synthase (EC 4.6.1.3) LMBR1 PF04791.11 CDI87207.1 - 0.71 8.3 7.1 1.3 7.4 4.9 1.5 1 0 0 1 1 1 0 LMBR1-like membrane protein RskA PF10099.4 CDI87209.1 - 0.0023 17.6 5.5 0.0023 17.6 3.8 8.0 2 1 4 7 7 7 1 Anti-sigma-K factor rskA K_channel_TID PF07941.6 CDI87209.1 - 0.74 10.0 30.4 4.9 7.4 17.7 5.0 2 1 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain SOBP PF15279.1 CDI87210.1 - 0.27 11.5 27.3 0.42 10.9 18.9 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein UCR_TM PF02921.9 CDI87210.1 - 1.1 9.5 0.0 1.1 9.5 0.0 2.9 3 1 0 3 3 3 0 Ubiquinol cytochrome reductase transmembrane region DUF1183 PF06682.7 CDI87210.1 - 3.2 7.2 23.7 5 6.6 16.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) DUF4366 PF14283.1 CDI87210.1 - 3.8 6.8 19.5 0.32 10.3 8.5 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4366) Peptidase_M56 PF05569.6 CDI87210.1 - 7.1 5.5 11.5 3.8 6.3 6.8 1.4 1 1 0 1 1 1 0 BlaR1 peptidase M56 LMBR1 PF04791.11 CDI87211.1 - 5.3 5.5 0.0 5.3 5.5 0.0 6.4 3 2 0 5 5 5 0 LMBR1-like membrane protein Med15 PF09606.5 CDI87212.1 - 0.0073 14.5 132.0 0.0099 14.1 91.5 1.1 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal CAF-1_p150 PF11600.3 CDI87212.1 - 0.0078 15.6 55.0 0.013 14.9 38.1 1.3 1 0 0 1 1 1 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal SPX PF03105.14 CDI87213.1 - 0.016 15.0 7.6 0.022 14.5 5.3 1.3 1 0 0 1 1 1 0 SPX domain Med15_fungi PF05397.7 CDI87213.1 - 0.024 14.6 0.3 0.024 14.6 0.2 1.7 1 1 0 1 1 1 0 Mediator complex subunit 15 Suf PF05843.9 CDI87213.1 - 0.087 12.5 9.3 0.14 11.8 6.4 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Hid1 PF12722.2 CDI87213.1 - 0.47 8.0 5.6 0.48 8.0 3.9 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Gag_spuma PF03276.9 CDI87213.1 - 1.1 7.5 18.6 1.7 6.8 12.9 1.2 1 0 0 1 1 1 0 Spumavirus gag protein TATR PF03430.8 CDI87213.1 - 1.6 7.2 11.1 2.2 6.8 7.7 1.1 1 0 0 1 1 1 0 Trans-activating transcriptional regulator DUF572 PF04502.8 CDI87213.1 - 1.9 7.6 16.5 2.3 7.3 11.5 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) FimP PF09766.4 CDI87213.1 - 5.4 5.9 16.8 7.4 5.5 11.6 1.2 1 0 0 1 1 1 0 Fms-interacting protein DUF844 PF05815.6 CDI87213.1 - 7 5.3 10.1 14 4.3 7.0 1.5 1 0 0 1 1 1 0 Baculovirus protein of unknown function (DUF844) FLO_LFY PF01698.11 CDI87213.1 - 7.3 5.3 11.2 10 4.8 7.8 1.2 1 0 0 1 1 1 0 Floricaula / Leafy protein HTH_23 PF13384.1 CDI87217.1 - 0.00043 19.8 0.1 0.0039 16.7 0.0 2.8 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.1 CDI87217.1 - 0.00046 20.1 0.1 0.0041 17.1 0.1 2.8 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_17 PF12728.2 CDI87217.1 - 0.19 11.9 0.0 0.6 10.4 0.0 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain DUF4207 PF13904.1 CDI87218.1 - 0.45 9.8 32.7 1.2 8.4 22.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4207) SOBP PF15279.1 CDI87218.1 - 0.67 10.2 17.6 0.95 9.7 12.2 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein PBP1_TM PF14812.1 CDI87218.1 - 1.3 9.3 8.4 0.22 11.8 2.3 2.3 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal SR-25 PF10500.4 CDI87219.1 - 0.0034 16.9 10.7 0.0034 16.9 7.4 3.5 1 1 2 3 3 3 1 Nuclear RNA-splicing-associated protein ThylakoidFormat PF11264.3 CDI87219.1 - 4 6.9 24.9 1.7 8.1 8.7 2.4 1 1 1 2 2 2 0 Thylakoid formation protein YopR_core PF09025.5 CDI87219.1 - 9.1 6.2 27.8 0.4 10.6 7.9 2.2 2 0 0 2 2 2 0 YopR Core RRM_5 PF13893.1 CDI87221.1 - 0.00036 20.3 0.0 0.0011 18.8 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) IncA PF04156.9 CDI87221.1 - 0.007 15.9 1.6 0.007 15.9 1.1 11.3 5 3 4 9 9 9 2 IncA protein RRM_6 PF14259.1 CDI87221.1 - 0.026 14.4 0.0 0.068 13.1 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CDI87221.1 - 0.057 13.0 0.0 0.18 11.4 0.0 1.9 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF812 PF05667.6 CDI87222.1 - 0.39 9.1 8.6 0.46 8.9 5.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF812) CDC27 PF09507.5 CDI87222.1 - 9.7 5.2 11.0 13 4.9 7.6 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 MIP-T3 PF10243.4 CDI87224.1 - 0.89 7.9 25.1 1 7.7 17.4 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 PRP38_assoc PF12871.2 CDI87224.1 - 1.5 9.4 88.8 1.5e+04 -15.7 61.6 3.2 1 1 0 1 1 1 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term HAD_2 PF13419.1 CDI87225.1 - 0.0082 16.3 0.3 4.5 7.4 0.1 2.4 1 1 0 2 2 2 2 Haloacid dehalogenase-like hydrolase MORN PF02493.15 CDI87226.1 - 4.3e-12 45.0 8.3 7.9e-08 31.5 1.8 3.7 3 0 0 3 3 3 3 MORN repeat LRR_4 PF12799.2 CDI87227.1 - 2e-16 59.2 12.1 5.5e-06 25.8 0.2 5.0 3 2 2 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CDI87227.1 - 3.6e-14 52.2 7.8 1.6e-06 27.7 1.2 3.8 2 1 1 3 3 3 3 Leucine rich repeat LRR_9 PF14580.1 CDI87227.1 - 6.5e-12 45.3 0.2 0.00018 21.1 0.4 2.7 2 1 0 2 2 2 2 Leucine-rich repeat LRR_6 PF13516.1 CDI87227.1 - 0.0012 18.6 9.7 1.4 9.2 0.1 5.6 5 1 1 6 6 6 2 Leucine Rich repeat LRR_1 PF00560.28 CDI87227.1 - 0.002 17.8 10.6 5.1 7.5 0.1 6.2 6 0 0 6 6 6 1 Leucine Rich Repeat LRR_7 PF13504.1 CDI87227.1 - 0.046 13.9 10.1 38 5.1 0.1 6.6 6 1 0 6 6 6 0 Leucine rich repeat EF-hand_1 PF00036.27 CDI87229.1 - 3.7e-17 60.2 1.4 2.9e-07 29.2 0.1 3.4 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.1 CDI87229.1 - 9.2e-17 60.9 0.2 2.3e-08 34.0 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 CDI87229.1 - 1.6e-16 58.6 4.9 6.9e-07 28.6 0.1 3.9 3 1 1 4 4 4 3 EF-hand domain EF-hand_9 PF14658.1 CDI87229.1 - 2.2e-11 43.5 0.0 1.5e-06 27.9 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.1 CDI87229.1 - 4.8e-09 35.1 0.7 0.00018 20.6 0.2 2.6 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.1 CDI87229.1 - 2.1e-06 27.2 3.4 0.0008 18.9 0.2 3.4 1 1 3 4 4 4 2 EF-hand domain pair EF-hand_like PF09279.6 CDI87229.1 - 0.045 13.7 0.0 0.096 12.7 0.0 1.5 1 0 0 1 1 1 0 Phosphoinositide-specific phospholipase C, efhand-like Rhamno_transf PF11316.3 CDI87229.1 - 0.06 12.5 0.0 0.071 12.3 0.0 1.2 1 0 0 1 1 1 0 Putative rhamnosyl transferase LNS2 PF08235.8 CDI87230.1 - 4.5e-65 218.0 0.0 6.7e-65 217.4 0.0 1.2 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.9 CDI87230.1 - 3.3e-28 97.5 0.0 6.3e-28 96.6 0.0 1.4 1 0 0 1 1 1 1 lipin, N-terminal conserved region DUF2369 PF10179.4 CDI87231.1 - 0.12 11.4 0.0 0.14 11.2 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2369) Kinesin PF00225.18 CDI87232.1 - 1e-85 287.4 3.8 1.6e-85 286.7 0.1 2.6 2 1 0 2 2 2 1 Kinesin motor domain LPP20 PF02169.11 CDI87232.1 - 0.38 10.8 5.0 0.11 12.5 0.4 2.3 2 0 0 2 2 2 0 LPP20 lipoprotein Effector_1 PF04518.7 CDI87232.1 - 3.8 6.4 18.8 0.018 14.0 2.8 2.6 1 1 1 2 2 2 0 Effector from type III secretion system Herpes_DNAp_acc PF04929.7 CDI87233.1 - 0.16 10.8 8.4 0.085 11.8 3.5 2.2 1 1 1 2 2 2 0 Herpes DNA replication accessory factor DUF4578 PF15147.1 CDI87233.1 - 0.42 11.0 7.3 0.19 12.0 3.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4578) DUF4200 PF13863.1 CDI87234.1 - 9.9e-12 44.9 16.4 9.9e-12 44.9 11.4 4.6 3 2 0 3 3 3 1 Domain of unknown function (DUF4200) HWE_HK PF07536.9 CDI87234.1 - 0.02 15.3 0.4 0.02 15.3 0.3 2.2 2 0 0 2 2 2 0 HWE histidine kinase DUF1664 PF07889.7 CDI87234.1 - 3.5 7.4 10.3 7.1 6.4 1.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF948 PF06103.6 CDI87234.1 - 4.3 7.2 10.3 2.3 8.1 1.2 3.5 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) ADK PF00406.17 CDI87235.1 - 2.7e-24 85.7 0.0 8.9e-14 51.6 0.0 2.6 2 0 0 2 2 2 2 Adenylate kinase AAA_17 PF13207.1 CDI87235.1 - 1.2e-06 29.3 0.0 0.0023 18.7 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.1 CDI87235.1 - 0.00064 19.6 11.5 0.0039 17.0 0.1 3.1 3 1 0 3 3 3 2 AAA domain Cytidylate_kin2 PF13189.1 CDI87235.1 - 0.0013 18.7 0.0 0.21 11.4 0.0 2.5 2 0 0 2 2 2 1 Cytidylate kinase-like family AAA_18 PF13238.1 CDI87235.1 - 0.0027 18.0 0.1 0.14 12.4 0.0 2.9 3 0 0 3 3 3 1 AAA domain dNK PF01712.14 CDI87235.1 - 0.022 14.6 0.0 0.054 13.4 0.0 1.6 1 0 0 1 1 1 0 Deoxynucleoside kinase TATR PF03430.8 CDI87236.1 - 0.35 9.4 18.1 0.4 9.2 12.6 1.0 1 0 0 1 1 1 0 Trans-activating transcriptional regulator Utp14 PF04615.8 CDI87236.1 - 0.41 8.7 38.7 0.51 8.4 26.8 1.1 1 0 0 1 1 1 0 Utp14 protein Caldesmon PF02029.10 CDI87236.1 - 0.64 8.3 34.2 0.79 8.0 23.7 1.1 1 0 0 1 1 1 0 Caldesmon Asp-B-Hydro_N PF05279.6 CDI87236.1 - 0.65 9.7 31.9 0.75 9.5 22.1 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region PAT1 PF09770.4 CDI87236.1 - 0.69 8.0 49.6 0.85 7.7 34.3 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 CDC27 PF09507.5 CDI87236.1 - 0.93 8.6 36.6 1.1 8.3 25.4 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 GAGA_bind PF06217.7 CDI87236.1 - 1.4 8.8 26.7 1.9 8.3 18.5 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family CDC45 PF02724.9 CDI87236.1 - 3.2 5.6 28.1 4.6 5.1 19.5 1.3 1 0 0 1 1 1 0 CDC45-like protein DNA_pol_viral_N PF00242.12 CDI87236.1 - 3.6 6.5 24.4 4.3 6.2 16.9 1.1 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain Med15 PF09606.5 CDI87236.1 - 6.9 4.7 58.8 9.1 4.3 40.8 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Hid1 PF12722.2 CDI87236.1 - 7.3 4.1 29.6 9.1 3.8 20.6 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Parvo_coat PF00740.13 CDI87236.1 - 8.6 5.1 26.0 10 4.9 18.0 1.0 1 0 0 1 1 1 0 Parvovirus coat protein VP2 PRA1 PF03208.14 CDI87237.1 - 0.013 14.8 1.4 0.015 14.6 1.0 1.1 1 0 0 1 1 1 0 PRA1 family protein DREPP PF05558.7 CDI87237.1 - 0.035 13.9 4.5 0.039 13.7 3.1 1.1 1 0 0 1 1 1 0 DREPP plasma membrane polypeptide FHIPEP PF00771.15 CDI87237.1 - 0.17 10.1 8.9 0.21 9.8 6.2 1.1 1 0 0 1 1 1 0 FHIPEP family Lipoprotein_2 PF00921.12 CDI87237.1 - 0.22 11.5 15.8 0.28 11.1 11.0 1.1 1 0 0 1 1 1 0 Borrelia lipoprotein Phostensin_N PF13916.1 CDI87237.1 - 0.22 11.5 2.6 0.39 10.7 1.8 1.4 1 0 0 1 1 1 0 PP1-regulatory protein, Phostensin N-terminal Cnd1_N PF12922.2 CDI87237.1 - 0.33 10.5 4.1 0.41 10.2 2.8 1.3 1 1 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1, N-term DUF1345 PF07077.6 CDI87237.1 - 0.33 10.4 7.4 0.42 10.1 5.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1345) DUF1282 PF06930.7 CDI87237.1 - 0.48 10.0 4.1 0.5 9.9 2.5 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1282) Flavi_NS4B PF01349.12 CDI87237.1 - 0.74 8.7 10.3 1.1 8.1 7.1 1.3 1 1 0 1 1 1 0 Flavivirus non-structural protein NS4B Herpes_UL20 PF04544.7 CDI87237.1 - 0.87 9.3 6.7 1.1 9.1 4.6 1.2 1 0 0 1 1 1 0 Herpesvirus egress protein UL20 Internalin_N PF12354.3 CDI87237.1 - 1 9.0 5.1 4.7 6.9 0.3 2.2 2 0 0 2 2 2 0 Bacterial adhesion/invasion protein N terminal DUF2946 PF11162.3 CDI87237.1 - 1.3 9.2 15.9 1.5 9.0 11.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2946) HipA_C PF07804.7 CDI87237.1 - 1.7 8.8 3.7 1 9.5 0.8 1.9 1 1 1 2 2 2 0 HipA-like C-terminal domain NnrS PF05940.7 CDI87237.1 - 8.6 5.1 15.0 13 4.5 10.4 1.3 1 1 0 1 1 1 0 NnrS protein CAF-1_p150 PF11600.3 CDI87238.1 - 0.012 14.9 28.2 0.012 14.9 19.6 3.3 2 1 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Conotoxin PF02950.12 CDI87238.1 - 0.067 14.0 0.4 0.067 14.0 0.3 7.1 2 1 1 3 3 3 0 Conotoxin DEAD PF00270.24 CDI87239.1 - 0.0014 18.1 0.0 0.0021 17.5 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Pox_Ag35 PF03286.9 CDI87239.1 - 4.6 6.7 10.6 7.2 6.0 7.3 1.3 1 1 0 1 1 1 0 Pox virus Ag35 surface protein SR-25 PF10500.4 CDI87240.1 - 0.0019 17.6 5.8 0.0062 16.0 4.0 1.9 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein AAA_16 PF13191.1 CDI87241.1 - 3.6e-06 27.0 2.1 3.6e-06 27.0 1.5 3.5 3 0 0 3 3 3 1 AAA ATPase domain Bac_luciferase PF00296.15 CDI87242.1 - 0.01 14.9 2.5 0.038 13.1 0.0 2.7 2 1 1 3 3 3 0 Luciferase-like monooxygenase DUF1469 PF07332.6 CDI87242.1 - 0.25 11.0 5.4 0.46 10.2 3.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1469) NAD_binding_1 PF00175.16 CDI87243.1 - 1.1e-05 25.9 13.6 4.3e-05 24.0 0.0 4.5 4 0 0 4 4 4 2 Oxidoreductase NAD-binding domain Isy1 PF06246.7 CDI87243.1 - 0.0047 16.3 0.2 0.0047 16.3 0.1 4.7 3 1 1 4 4 4 1 Isy1-like splicing family SR-25 PF10500.4 CDI87243.1 - 0.0086 15.5 1.2 0.0086 15.5 0.8 8.5 7 2 1 9 9 9 1 Nuclear RNA-splicing-associated protein Rhabdo_M2 PF04785.7 CDI87243.1 - 0.016 14.2 0.2 0.52 9.3 0.0 2.6 2 0 0 2 2 2 0 Rhabdovirus matrix protein M2 Tau95 PF09734.4 CDI87243.1 - 0.41 9.9 20.9 0.29 10.4 3.1 3.4 3 0 0 3 3 3 0 RNA polymerase III transcription factor (TF)IIIC subunit CAP_N PF01213.14 CDI87244.1 - 0.52 9.5 3.6 0.62 9.2 2.5 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal SR-25 PF10500.4 CDI87245.1 - 0.0017 17.8 48.2 0.0049 16.3 5.1 3.4 3 0 0 3 3 3 2 Nuclear RNA-splicing-associated protein SprA-related PF12118.3 CDI87245.1 - 0.0081 15.5 38.3 0.38 10.0 3.4 3.4 3 0 0 3 3 3 3 SprA-related family Apt1 PF10351.4 CDI87245.1 - 0.017 13.9 0.2 0.017 13.9 0.1 2.9 3 0 0 3 3 3 0 Golgi-body localisation protein domain SPX PF03105.14 CDI87245.1 - 0.22 11.2 13.3 0.83 9.3 0.3 3.2 3 0 0 3 3 3 0 SPX domain TFIIA PF03153.8 CDI87245.1 - 1.2 8.9 38.9 1.3 8.8 5.5 3.2 3 0 0 3 3 3 0 Transcription factor IIA, alpha/beta subunit Phage_CRI PF05144.9 CDI87245.1 - 2.2 7.3 8.4 0.86 8.6 0.3 2.1 2 0 0 2 2 2 0 Phage replication protein CRI DUF4614 PF15391.1 CDI87245.1 - 2.5 7.8 29.5 0.93 9.2 5.6 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4614) Gti1_Pac2 PF09729.4 CDI87245.1 - 4.1 7.2 13.9 1.5 8.6 2.3 3.1 3 0 0 3 3 3 0 Gti1/Pac2 family Suf PF05843.9 CDI87245.1 - 5.6 6.6 17.4 1.1 8.8 1.6 3.0 3 0 0 3 3 3 0 Suppressor of forked protein (Suf) DDHD PF02862.12 CDI87245.1 - 6 6.5 22.1 2.6 7.7 0.5 3.2 3 0 0 3 3 3 0 DDHD domain RAB3GAP2_N PF14655.1 CDI87245.1 - 7.7 5.3 14.3 0.53 9.2 2.8 2.2 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus DUF2489 PF10675.4 CDI87245.1 - 8.2 6.1 18.1 11 5.7 6.6 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2489) DUF445 PF04286.7 CDI87246.1 - 0.14 11.6 11.8 0.012 15.1 2.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF445) DUF572 PF04502.8 CDI87246.1 - 4.7 6.3 36.5 2.8 7.0 14.5 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF572) LMBR1 PF04791.11 CDI87246.1 - 6.3 5.2 5.3 2.9 6.3 0.1 2.0 2 0 0 2 2 2 0 LMBR1-like membrane protein HI0933_like PF03486.9 CDI87246.1 - 7.7 4.8 21.1 0.017 13.6 6.0 2.2 2 0 0 2 2 2 0 HI0933-like protein His_Phos_1 PF00300.17 CDI87247.1 - 1.3e-07 31.8 8.9 1.3e-07 31.8 6.2 1.9 1 1 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) Pex14_N PF04695.8 CDI87247.1 - 0.0043 17.0 10.0 0.0043 17.0 7.0 2.7 3 0 0 3 3 3 1 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF947 PF06102.7 CDI87247.1 - 0.054 13.3 18.3 0.03 14.1 1.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF947) zf-DHHC PF01529.15 CDI87247.1 - 0.21 10.9 4.5 0.69 9.2 0.3 2.2 2 0 0 2 2 2 0 DHHC palmitoyltransferase Mu-like_Pro PF10123.4 CDI87247.1 - 0.34 10.3 28.5 0.055 12.9 14.6 2.0 2 0 0 2 2 2 0 Mu-like prophage I protein YABBY PF04690.8 CDI87247.1 - 0.43 10.7 7.2 0.36 11.0 1.1 2.2 2 0 0 2 2 2 0 YABBY protein DUF912 PF06024.7 CDI87247.1 - 0.43 10.6 10.5 1.9 8.5 1.8 2.4 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF702 PF05142.7 CDI87247.1 - 0.63 10.1 10.8 3.4 7.8 3.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF702) Dala_Dala_lig_N PF01820.16 CDI87247.1 - 0.79 10.0 9.6 6.5 7.0 0.4 2.5 2 0 0 2 2 2 0 D-ala D-ala ligase N-terminus TraT PF05818.7 CDI87247.1 - 0.89 8.9 13.7 0.025 14.0 2.6 2.3 2 0 0 2 2 2 0 Enterobacterial TraT complement resistance protein DUF3708 PF12501.3 CDI87247.1 - 0.93 9.3 15.6 0.061 13.1 2.4 3.1 3 0 0 3 3 3 0 Phosphate ATP-binding cassette transporter Spore_coat_CotO PF14153.1 CDI87247.1 - 0.96 8.8 24.8 0.92 8.9 9.1 2.3 2 0 0 2 2 2 0 Spore coat protein CotO DDRGK PF09756.4 CDI87247.1 - 1.1 8.6 26.6 2.2 7.6 9.7 2.3 2 0 0 2 2 2 0 DDRGK domain AUX_IAA PF02309.11 CDI87247.1 - 1.2 8.8 10.5 0.54 9.9 3.4 2.1 2 0 0 2 2 2 0 AUX/IAA family FAD-oxidase_C PF02913.14 CDI87247.1 - 3.1 7.0 7.5 9 5.5 5.2 1.8 1 1 0 1 1 1 0 FAD linked oxidases, C-terminal domain DUF4557 PF15101.1 CDI87247.1 - 3.9 7.2 32.1 0.45 10.3 11.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4557) DUF3474 PF11960.3 CDI87247.1 - 4.2 7.3 5.7 4.9 7.1 1.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3474) Folliculin PF11704.3 CDI87247.1 - 5.1 6.6 15.3 3 7.4 4.1 2.5 2 0 0 2 2 2 0 Vesicle coat protein involved in Golgi to plasma membrane transport MMR1 PF08505.5 CDI87247.1 - 5.3 7.0 17.6 0.75 9.7 5.7 2.1 2 0 0 2 2 2 0 Mitochondrial Myo2 receptor-related protein CRF1 PF10380.4 CDI87247.1 - 5.4 7.3 9.1 8.8 6.6 2.5 2.4 2 0 0 2 2 2 0 Transcription factor CRF1 Folate_carrier PF01770.13 CDI87247.1 - 5.7 5.3 9.2 2.2 6.7 2.0 2.2 2 0 0 2 2 2 0 Reduced folate carrier DUF2072 PF09845.4 CDI87247.1 - 6.1 6.7 8.0 12 5.8 2.1 2.3 2 0 0 2 2 2 0 Zn-ribbon containing protein (DUF2072) AIF_C PF14721.1 CDI87247.1 - 7.7 6.7 12.7 7.9 6.7 4.3 2.3 2 0 0 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term FlaG PF03646.10 CDI87247.1 - 8.4 6.5 30.1 9.5 6.4 11.9 2.4 2 0 0 2 2 2 0 FlaG protein SR-25 PF10500.4 CDI87250.1 - 0.00011 21.8 6.1 0.00027 20.5 1.8 2.3 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein DUF1635 PF07795.6 CDI87250.1 - 0.29 10.4 12.6 1.4 8.2 6.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1635) FHIPEP PF00771.15 CDI87250.1 - 0.43 8.8 10.0 0.55 8.4 6.9 1.3 1 1 0 1 1 1 0 FHIPEP family RD3 PF14473.1 CDI87250.1 - 0.92 8.9 8.7 0.042 13.3 1.7 2.0 3 0 0 3 3 3 0 RD3 protein DUF3994 PF13159.1 CDI87250.1 - 0.99 9.7 4.1 0.47 10.7 1.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3994) TAF1D PF15333.1 CDI87250.1 - 2.5 7.8 10.3 3.6 7.3 2.0 2.4 2 1 0 2 2 2 0 TATA box-binding protein-associated factor 1D DUF2477 PF10631.4 CDI87250.1 - 3.1 7.9 7.2 12 6.0 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2477) LIM_bind PF01803.11 CDI87250.1 - 6.4 5.8 13.1 2.1 7.3 4.9 2.0 2 0 0 2 2 2 0 LIM-domain binding protein Nup54 PF13874.1 CDI87250.1 - 7.9 6.1 24.5 0.011 15.3 2.9 3.2 1 1 2 3 3 2 0 Nucleoporin complex subunit 54 Pap_E4 PF02711.9 CDI87250.1 - 8.3 7.3 11.1 5.2 7.9 4.0 2.3 2 0 0 2 2 2 0 E4 protein DUF1754 PF08555.5 CDI87250.1 - 8.6 7.0 10.1 5.8 7.5 5.2 1.9 2 0 0 2 2 2 0 Eukaryotic family of unknown function (DUF1754) Plasmodium_HRP PF05403.6 CDI87251.1 - 2.2 7.8 11.5 22 4.5 8.0 2.2 1 1 0 1 1 1 0 Plasmodium histidine-rich protein (HRPII/III) TACC PF05010.9 CDI87252.1 - 0.017 14.8 0.9 0.021 14.5 0.6 1.1 1 0 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC) Tmemb_cc2 PF10267.4 CDI87252.1 - 0.15 10.6 3.3 0.2 10.2 2.3 1.2 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein Vicilin_N PF04702.7 CDI87252.1 - 9.9 5.7 13.5 4.8 6.7 1.0 2.0 2 0 0 2 2 2 0 Vicilin N terminal region PAT1 PF09770.4 CDI87253.1 - 0.88 7.7 30.8 0.95 7.6 21.4 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Gly-zipper_OmpA PF13436.1 CDI87253.1 - 1.5 8.4 21.8 0.043 13.4 7.2 2.1 2 0 0 2 2 2 0 Glycine-zipper containing OmpA-like membrane domain FAM60A PF15396.1 CDI87253.1 - 1.7 8.3 10.9 1.9 8.2 7.5 1.1 1 0 0 1 1 1 0 Protein Family FAM60A DUF2000 PF09391.5 CDI87253.1 - 2.1 8.0 5.7 0.19 11.4 0.6 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2000) RR_TM4-6 PF06459.7 CDI87253.1 - 2.4 7.9 17.2 2.6 7.8 11.9 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 RabGAP-TBC PF00566.13 CDI87253.1 - 2.5 7.5 9.5 2.6 7.4 6.6 1.1 1 0 0 1 1 1 0 Rab-GTPase-TBC domain DDHD PF02862.12 CDI87253.1 - 3.2 7.4 14.1 3.9 7.2 9.8 1.1 1 0 0 1 1 1 0 DDHD domain Cyto_heme_lyase PF01265.12 CDI87253.1 - 3.3 7.2 12.8 3.2 7.2 8.8 1.1 1 0 0 1 1 1 0 Cytochrome c/c1 heme lyase Hid1 PF12722.2 CDI87253.1 - 3.7 5.0 15.9 3.9 5.0 11.0 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein BTV_NS2 PF04514.7 CDI87253.1 - 5.7 5.7 15.3 5.9 5.6 10.6 1.0 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 ARGLU PF15346.1 CDI87253.1 - 7.5 6.3 27.6 10 5.8 19.1 1.1 1 0 0 1 1 1 0 Arginine and glutamate-rich 1 Presenilin PF01080.12 CDI87253.1 - 8.1 5.1 11.3 8.7 5.0 7.8 1.0 1 0 0 1 1 1 0 Presenilin CMV_1a PF12467.3 CDI87253.1 - 8.5 6.7 12.0 8.8 6.6 8.3 1.1 1 0 0 1 1 1 0 Cucumber mosaic virus 1a protein family Macoilin PF09726.4 CDI87254.1 - 0.0042 15.4 32.7 0.0055 15.0 22.7 1.1 1 0 0 1 1 1 1 Transmembrane protein Ribosomal_60s PF00428.14 CDI87254.1 - 0.13 12.6 11.0 0.34 11.3 7.6 1.7 1 0 0 1 1 1 0 60s Acidic ribosomal protein CAF-1_p150 PF11600.3 CDI87254.1 - 0.19 11.0 45.7 0.25 10.7 31.6 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal GAGA_bind PF06217.7 CDI87254.1 - 0.49 10.3 43.6 0.61 9.9 30.2 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family Daxx PF03344.10 CDI87254.1 - 0.71 8.2 40.8 0.85 8.0 28.3 1.0 1 0 0 1 1 1 0 Daxx Family PAT1 PF09770.4 CDI87254.1 - 1.6 6.8 93.2 1.9 6.6 64.6 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Caldesmon PF02029.10 CDI87254.1 - 2.2 6.6 38.1 2.7 6.2 26.4 1.1 1 0 0 1 1 1 0 Caldesmon Utp14 PF04615.8 CDI87254.1 - 2.2 6.3 51.1 2.6 6.0 35.4 1.0 1 0 0 1 1 1 0 Utp14 protein Draxin PF15550.1 CDI87254.1 - 2.3 7.7 39.9 2.9 7.4 27.7 1.1 1 0 0 1 1 1 0 Draxin PLRV_ORF5 PF01690.12 CDI87254.1 - 5.6 5.9 40.6 7.3 5.6 28.2 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein SR-25 PF10500.4 CDI87255.1 - 0.00034 20.1 15.4 0.00034 20.1 10.7 4.3 3 2 0 3 3 3 1 Nuclear RNA-splicing-associated protein CAF-1_p150 PF11600.3 CDI87255.1 - 0.00051 19.4 23.3 0.00051 19.4 16.1 4.0 4 0 0 4 4 4 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal ETRAMP PF09716.5 CDI87255.1 - 2.5 8.1 23.2 0.3 11.0 0.7 4.8 2 1 2 4 4 4 0 Malarial early transcribed membrane protein (ETRAMP) PAT1 PF09770.4 CDI87256.1 - 0.0014 17.0 95.5 0.0017 16.6 66.2 1.0 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 Methyltransf_26 PF13659.1 CDI87256.1 - 0.024 14.6 0.0 0.19 11.7 0.0 2.2 1 1 0 1 1 1 0 Methyltransferase domain POR PF01558.13 CDI87256.1 - 0.051 13.4 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 Pyruvate ferredoxin/flavodoxin oxidoreductase RAP1 PF07218.6 CDI87256.1 - 0.069 11.2 16.3 0.093 10.8 11.3 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) CAF-1_p150 PF11600.3 CDI87256.1 - 0.47 9.7 63.7 3.3 7.0 44.3 2.0 1 1 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF3100 PF11299.3 CDI87257.1 - 0.05 12.8 0.0 0.13 11.4 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3100) RskA PF10099.4 CDI87257.1 - 1.7 8.3 25.4 2.5 7.8 9.5 2.6 2 1 1 3 3 3 0 Anti-sigma-K factor rskA DUF2652 PF10851.3 CDI87257.1 - 1.8 8.6 7.4 11 6.0 0.4 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF2652) DNA_pol_alpha_N PF12254.3 CDI87257.1 - 5.3 6.9 6.7 0.38 10.6 0.8 2.0 2 0 0 2 2 2 0 DNA polymerase alpha subunit p180 N terminal DUF2324 PF10086.4 CDI87257.1 - 9.3 5.3 12.7 2.9 7.0 1.7 2.4 2 0 0 2 2 2 0 Putative membrane peptidase family (DUF2324) Spt20 PF12090.3 CDI87258.1 - 0.00013 21.3 23.1 0.0049 16.2 1.8 3.6 4 0 0 4 4 4 3 Spt20 family DUF755 PF05501.6 CDI87258.1 - 2.1 8.4 47.7 0.45 10.5 10.2 3.7 3 0 0 3 3 3 0 Domain of unknown function (DUF755) Med15 PF09606.5 CDI87260.1 - 0.031 12.4 20.4 0.032 12.4 14.2 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal PAT1 PF09770.4 CDI87260.1 - 0.13 10.5 11.4 0.11 10.7 7.9 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF4175 PF13779.1 CDI87260.1 - 1.3 6.6 16.5 1.4 6.5 11.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) BAF1_ABF1 PF04684.8 CDI87260.1 - 3.7 6.2 15.2 5 5.8 10.6 1.4 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor WD40 PF00400.27 CDI87262.1 - 1.8e-38 129.0 30.5 1e-06 28.3 1.2 12.4 13 1 0 13 13 13 8 WD domain, G-beta repeat PQQ_2 PF13360.1 CDI87262.1 - 3.2e-05 23.5 0.0 0.04 13.3 0.0 2.9 1 1 2 3 3 3 3 PQQ-like domain PQQ_3 PF13570.1 CDI87262.1 - 4.9e-05 23.4 2.7 55 4.2 0.0 7.3 8 0 0 8 8 8 0 PQQ-like domain eIF2A PF08662.6 CDI87262.1 - 0.00052 19.7 0.0 0.028 14.1 0.0 3.2 3 1 1 4 4 4 1 Eukaryotic translation initiation factor eIF2A Reo_sigmaC PF04582.7 CDI87263.1 - 2e-05 23.9 10.9 3.6e-05 23.1 1.9 2.3 2 0 0 2 2 2 2 Reovirus sigma C capsid protein IncA PF04156.9 CDI87263.1 - 0.00027 20.6 38.6 0.0068 16.0 0.8 4.3 1 1 3 4 4 4 3 IncA protein Baculo_PEP_C PF04513.7 CDI87263.1 - 0.0014 18.4 7.9 0.016 15.0 0.2 3.5 2 1 0 3 3 3 1 Baculovirus polyhedron envelope protein, PEP, C terminus GAS PF13851.1 CDI87263.1 - 0.0015 17.7 11.1 0.0015 17.7 7.7 3.9 2 2 1 4 4 4 1 Growth-arrest specific micro-tubule binding ATG16 PF08614.6 CDI87263.1 - 0.014 15.2 15.1 0.014 15.2 10.4 3.2 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) BLOC1_2 PF10046.4 CDI87263.1 - 0.021 14.9 20.4 0.12 12.5 0.3 4.8 2 2 3 5 5 5 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF1664 PF07889.7 CDI87263.1 - 0.26 11.0 19.4 0.045 13.5 3.9 4.2 2 2 2 4 4 4 0 Protein of unknown function (DUF1664) AAA_13 PF13166.1 CDI87263.1 - 0.56 8.5 22.5 0.016 13.7 5.2 2.2 2 0 0 2 2 2 0 AAA domain DUF948 PF06103.6 CDI87263.1 - 0.79 9.6 4.8 1.1 9.1 0.6 3.2 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Laminin_II PF06009.7 CDI87263.1 - 1.1 9.0 18.5 0.07 12.8 3.5 3.9 2 2 3 5 5 5 0 Laminin Domain II DivIVA PF05103.8 CDI87263.1 - 1.7 8.7 27.0 2.1 8.4 7.2 4.3 3 2 1 4 4 4 0 DivIVA protein Syntaxin-6_N PF09177.6 CDI87263.1 - 2.6 8.4 18.4 0.054 13.8 4.9 3.5 3 1 0 4 4 4 0 Syntaxin 6, N-terminal Cauli_AT PF03233.8 CDI87263.1 - 2.9 7.5 12.2 0.22 11.2 2.7 2.7 2 1 0 3 3 3 0 Aphid transmission protein Scaffolding_pro PF11418.3 CDI87263.1 - 3.3 8.0 11.8 0.79 10.0 4.2 2.8 2 1 0 2 2 2 0 Phi29 scaffolding protein TMF_DNA_bd PF12329.3 CDI87263.1 - 7.8 6.3 40.1 0.11 12.3 0.5 5.0 4 1 0 4 4 4 0 TATA element modulatory factor 1 DNA binding Glyco_hydro_77 PF02446.12 CDI87264.1 - 5.7e-106 355.0 0.2 1.1e-85 288.0 0.3 2.1 2 0 0 2 2 2 2 4-alpha-glucanotransferase Ant_C PF05586.6 CDI87265.1 - 0.00027 21.3 1.2 0.00032 21.0 0.8 1.1 1 0 0 1 1 1 1 Anthrax receptor C-terminus region Pex14_N PF04695.8 CDI87265.1 - 0.13 12.2 3.9 0.14 12.1 2.7 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region V_ATPase_I PF01496.14 CDI87266.1 - 2.2 6.0 12.0 3.4 5.4 8.3 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family ING PF12998.2 CDI87266.1 - 9.3 6.5 13.1 3 8.1 0.1 3.4 3 0 0 3 3 3 0 Inhibitor of growth proteins N-terminal histone-binding Med15 PF09606.5 CDI87267.1 - 0.023 12.9 70.7 0.027 12.7 49.0 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Caldesmon PF02029.10 CDI87267.1 - 0.04 12.3 18.3 0.046 12.1 12.7 1.1 1 0 0 1 1 1 0 Caldesmon Daxx PF03344.10 CDI87267.1 - 0.14 10.6 24.0 0.17 10.3 16.6 1.1 1 0 0 1 1 1 0 Daxx Family Hid1 PF12722.2 CDI87267.1 - 0.18 9.4 20.4 0.18 9.4 14.1 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF3801 PF12687.2 CDI87267.1 - 0.25 10.8 17.0 0.31 10.5 11.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3801) FLO_LFY PF01698.11 CDI87267.1 - 0.28 10.0 17.8 0.36 9.6 12.3 1.3 1 0 0 1 1 1 0 Floricaula / Leafy protein FAM60A PF15396.1 CDI87267.1 - 0.28 10.9 17.4 0.37 10.5 12.1 1.1 1 0 0 1 1 1 0 Protein Family FAM60A Parvo_coat PF00740.13 CDI87267.1 - 0.28 10.0 20.5 0.34 9.8 14.2 1.3 1 0 0 1 1 1 0 Parvovirus coat protein VP2 GAGA_bind PF06217.7 CDI87267.1 - 0.43 10.5 17.8 0.5 10.2 12.3 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family SAGA-Tad1 PF12767.2 CDI87267.1 - 0.47 10.0 24.2 0.61 9.6 16.8 1.2 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit CDC27 PF09507.5 CDI87267.1 - 0.59 9.3 30.1 0.67 9.1 20.9 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 PRP1_N PF06424.7 CDI87267.1 - 0.59 10.4 19.0 0.86 9.9 13.2 1.3 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal DUF966 PF06136.8 CDI87267.1 - 1.8 7.8 16.8 2.1 7.6 11.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Neur_chan_memb PF02932.11 CDI87267.1 - 1.8 8.3 13.2 2.2 8.1 9.1 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Nop14 PF04147.7 CDI87267.1 - 2.2 6.0 21.5 2.6 5.8 14.9 1.0 1 0 0 1 1 1 0 Nop14-like family DUF4647 PF15504.1 CDI87267.1 - 2.9 6.6 24.6 3.6 6.3 17.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4647) DUF1675 PF07897.6 CDI87267.1 - 3.2 7.5 18.7 3.7 7.3 13.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) TFIIA PF03153.8 CDI87267.1 - 3.4 7.4 53.8 3.9 7.2 37.3 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Asp-B-Hydro_N PF05279.6 CDI87267.1 - 3.5 7.4 21.0 4.2 7.1 14.6 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region SOBP PF15279.1 CDI87267.1 - 4.2 7.6 19.6 5.5 7.2 13.6 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein SAPS PF04499.10 CDI87267.1 - 5.5 5.5 23.4 6.8 5.2 16.2 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF4551 PF15087.1 CDI87267.1 - 5.8 5.1 14.1 6.3 5.0 9.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Peptidase_S64 PF08192.6 CDI87267.1 - 8.8 4.5 18.2 10 4.3 12.6 1.0 1 0 0 1 1 1 0 Peptidase family S64 Herpes_DNAp_acc PF04929.7 CDI87267.1 - 9.5 5.0 16.6 11 4.8 11.5 1.2 1 0 0 1 1 1 0 Herpes DNA replication accessory factor DUF2205 PF10224.4 CDI87269.1 - 0.016 14.7 9.2 0.016 14.7 6.4 2.9 1 1 1 2 2 1 0 Predicted coiled-coil protein (DUF2205) Med15 PF09606.5 CDI87269.1 - 0.033 12.4 74.3 0.041 12.1 51.5 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Exonuc_VII_L PF02601.10 CDI87269.1 - 0.069 12.3 22.0 0.081 12.1 15.2 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit SPX PF03105.14 CDI87269.1 - 0.14 11.9 18.0 0.19 11.5 12.5 1.3 1 0 0 1 1 1 0 SPX domain GAGA_bind PF06217.7 CDI87269.1 - 0.3 11.0 20.4 0.35 10.7 14.2 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family Lin-8 PF03353.10 CDI87269.1 - 0.55 9.4 24.5 0.66 9.2 17.0 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist DUF4045 PF13254.1 CDI87269.1 - 0.58 9.3 24.3 0.71 9.0 16.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Dapper PF15268.1 CDI87269.1 - 0.82 8.3 33.1 0.96 8.1 23.0 1.1 1 0 0 1 1 1 0 Dapper Daxx PF03344.10 CDI87269.1 - 0.88 7.9 26.7 1.1 7.6 18.5 1.1 1 0 0 1 1 1 0 Daxx Family FlaC_arch PF05377.6 CDI87269.1 - 1.1 9.2 4.9 2.7 7.9 2.7 2.2 1 1 0 1 1 1 0 Flagella accessory protein C (FlaC) Activator_LAG-3 PF11498.3 CDI87269.1 - 1.5 7.4 69.8 1.9 7.1 48.4 1.3 1 0 0 1 1 1 0 Transcriptional activator LAG-3 TT_ORF1 PF02956.9 CDI87269.1 - 1.6 7.0 14.6 1.8 6.8 10.1 1.1 1 0 0 1 1 1 0 TT viral orf 1 BTV_NS2 PF04514.7 CDI87269.1 - 2 7.2 17.0 2.6 6.8 11.8 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Neur_chan_memb PF02932.11 CDI87269.1 - 2 8.2 17.4 2.6 7.8 12.0 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Lact-deh-memb PF09330.6 CDI87269.1 - 2.1 7.6 7.8 4.9 6.4 5.1 1.7 1 1 1 2 2 2 0 D-lactate dehydrogenase, membrane binding FLO_LFY PF01698.11 CDI87269.1 - 2.3 6.9 19.4 2.9 6.6 13.5 1.2 1 0 0 1 1 1 0 Floricaula / Leafy protein DUF572 PF04502.8 CDI87269.1 - 2.7 7.1 26.4 3.3 6.8 18.3 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) SOBP PF15279.1 CDI87269.1 - 2.7 8.2 25.3 3.1 8.1 17.6 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein AvrE PF11725.3 CDI87269.1 - 3.1 4.6 28.9 3.9 4.3 20.0 1.2 1 0 0 1 1 1 0 Pathogenicity factor Asp-B-Hydro_N PF05279.6 CDI87269.1 - 4.2 7.1 23.8 5 6.9 16.5 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Zip PF02535.17 CDI87269.1 - 4.4 6.2 5.3 5.8 5.8 3.7 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter PAT1 PF09770.4 CDI87269.1 - 4.6 5.3 65.1 5.4 5.1 45.1 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 vMSA PF00695.14 CDI87269.1 - 5.7 6.0 13.5 7.7 5.6 9.4 1.3 1 0 0 1 1 1 0 Major surface antigen from hepadnavirus Hist_deacetyl PF00850.14 CDI87269.1 - 5.8 6.1 9.0 7.2 5.8 6.2 1.2 1 0 0 1 1 1 0 Histone deacetylase domain Plasmodium_Vir PF05795.6 CDI87269.1 - 6.7 5.8 5.7 9 5.3 4.0 1.3 1 0 0 1 1 1 0 Plasmodium vivax Vir protein YjgP_YjgQ PF03739.9 CDI87269.1 - 7.2 5.2 10.6 8.2 5.0 7.4 1.1 1 0 0 1 1 1 0 Predicted permease YjgP/YjgQ family Hid1 PF12722.2 CDI87269.1 - 7.5 4.0 24.8 8.8 3.8 17.2 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein PLRV_ORF5 PF01690.12 CDI87269.1 - 9.5 5.2 24.7 11 4.9 17.1 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Utp14 PF04615.8 CDI87270.1 - 6.4 4.8 33.5 1.7 6.7 15.4 2.0 2 0 0 2 2 2 0 Utp14 protein MACPF PF01823.14 CDI87271.1 - 0.2 11.3 6.3 0.28 10.8 4.4 1.2 1 0 0 1 1 1 0 MAC/Perforin domain DUF1635 PF07795.6 CDI87271.1 - 0.22 10.8 4.4 0.27 10.5 3.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) DUF572 PF04502.8 CDI87271.1 - 0.52 9.4 18.5 0.7 9.0 12.8 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Hex_IIIa PF02455.11 CDI87271.1 - 5.7 5.5 15.8 6.8 5.2 11.0 1.0 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) GP40 PF11025.3 CDI87271.1 - 6.1 6.3 16.7 0.29 10.6 7.2 1.8 1 1 1 2 2 2 0 Glycoprotein GP40 of Cryptosporidium DUF1183 PF06682.7 CDI87271.1 - 6.8 6.1 14.8 7.5 6.0 10.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) RICTOR_N PF14664.1 CDI87272.1 - 1.1 7.8 5.5 3 6.3 3.8 1.8 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR, N-term AAA_23 PF13476.1 CDI87272.1 - 3.7 7.8 69.8 1.6 9.0 9.1 6.2 6 0 0 6 6 6 0 AAA domain PAT1 PF09770.4 CDI87274.1 - 4.1e-06 25.3 33.7 4.5e-06 25.2 23.3 1.1 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 Ribosomal_60s PF00428.14 CDI87274.1 - 0.0016 18.8 22.7 0.1 13.0 3.7 2.5 2 0 0 2 2 2 2 60s Acidic ribosomal protein CDC45 PF02724.9 CDI87274.1 - 0.013 13.5 13.7 0.017 13.1 9.5 1.1 1 0 0 1 1 1 0 CDC45-like protein Daxx PF03344.10 CDI87274.1 - 0.047 12.1 18.6 0.053 12.0 12.9 1.0 1 0 0 1 1 1 0 Daxx Family Utp14 PF04615.8 CDI87274.1 - 0.061 11.5 22.4 0.074 11.2 15.5 1.1 1 0 0 1 1 1 0 Utp14 protein SARG PF15385.1 CDI87274.1 - 0.069 12.5 23.9 0.084 12.2 16.5 1.1 1 0 0 1 1 1 0 Specifically androgen-regulated gene protein Ycf1 PF05758.7 CDI87274.1 - 0.073 10.7 13.7 0.09 10.4 9.5 1.0 1 0 0 1 1 1 0 Ycf1 Dicty_REP PF05086.7 CDI87274.1 - 0.081 10.6 16.4 0.1 10.3 11.4 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Macoilin PF09726.4 CDI87274.1 - 0.12 10.6 17.6 0.15 10.3 12.2 1.2 1 0 0 1 1 1 0 Transmembrane protein Spc7_N PF15402.1 CDI87274.1 - 0.12 10.3 21.5 0.13 10.2 14.9 1.1 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 Shadoo PF14999.1 CDI87274.1 - 0.13 12.1 17.0 0.17 11.7 0.1 2.7 3 0 0 3 3 3 0 Shadow of prion protein, neuroprotective SAPS PF04499.10 CDI87274.1 - 0.16 10.6 17.3 0.2 10.2 12.0 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Dapper PF15268.1 CDI87274.1 - 0.3 9.8 27.1 0.4 9.4 18.8 1.1 1 0 0 1 1 1 0 Dapper Hid1 PF12722.2 CDI87274.1 - 0.71 7.4 22.6 0.93 7.0 15.6 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF4220 PF13968.1 CDI87274.1 - 0.78 8.7 4.4 0.99 8.4 3.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4220) DUF1183 PF06682.7 CDI87274.1 - 0.81 9.2 25.8 1.2 8.6 17.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) DUF2146 PF10220.4 CDI87274.1 - 0.99 7.3 15.9 1.3 6.8 11.1 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2146) SR-25 PF10500.4 CDI87274.1 - 1.1 8.7 35.1 1.8 8.0 9.1 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Herpes_env PF01673.13 CDI87274.1 - 1.9 6.9 11.7 2.2 6.7 8.1 1.2 1 0 0 1 1 1 0 Herpesvirus putative major envelope glycoprotein Peptidase_S49_N PF08496.5 CDI87274.1 - 3.2 7.5 13.6 18 5.1 9.3 2.1 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Cellulose_synt PF03552.9 CDI87274.1 - 3.3 5.9 4.6 3.6 5.7 3.2 1.1 1 0 0 1 1 1 0 Cellulose synthase Peptidase_U57 PF05582.7 CDI87274.1 - 3.7 6.4 10.6 5.9 5.7 7.4 1.3 1 0 0 1 1 1 0 YabG peptidase U57 SRP-alpha_N PF04086.8 CDI87274.1 - 4.9 6.4 26.3 7.3 5.8 18.3 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal SpaB_C PF14028.1 CDI87274.1 - 6.5 6.2 15.2 1.4 8.4 5.1 2.1 2 0 0 2 2 2 0 SpaB C-terminal domain vMSA PF00695.14 CDI87274.1 - 6.7 5.8 10.2 8 5.5 7.1 1.2 1 0 0 1 1 1 0 Major surface antigen from hepadnavirus LMBR1 PF04791.11 CDI87275.1 - 1.1 7.7 13.5 0.078 11.5 6.1 1.5 2 0 0 2 2 2 0 LMBR1-like membrane protein Seryl_tRNA_N PF02403.17 CDI87276.1 - 1.5e-20 73.1 1.5 1.5e-20 73.1 1.1 3.2 3 0 0 3 3 3 1 Seryl-tRNA synthetase N-terminal domain Spt20 PF12090.3 CDI87276.1 - 0.0025 17.1 12.4 0.019 14.2 0.2 2.3 2 0 0 2 2 2 2 Spt20 family tRNA-synt_2b PF00587.20 CDI87276.1 - 0.021 14.3 0.0 0.03 13.8 0.0 1.4 1 1 0 1 1 1 0 tRNA synthetase class II core domain (G, H, P, S and T) Folliculin PF11704.3 CDI87276.1 - 1.3 8.5 8.0 5.7 6.4 0.0 2.3 2 0 0 2 2 2 0 Vesicle coat protein involved in Golgi to plasma membrane transport RAP1 PF07218.6 CDI87277.1 - 7.3e-05 21.0 25.5 0.00011 20.5 17.7 1.3 1 0 0 1 1 1 1 Rhoptry-associated protein 1 (RAP-1) IncA PF04156.9 CDI87277.1 - 0.0041 16.7 11.7 0.0041 16.7 8.1 3.7 2 1 0 2 2 2 1 IncA protein Ycf1 PF05758.7 CDI87277.1 - 0.068 10.8 34.8 0.19 9.3 18.8 2.3 2 0 0 2 2 2 0 Ycf1 PAT1 PF09770.4 CDI87277.1 - 0.8 7.8 99.6 0.008 14.4 51.5 2.1 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 Macoilin PF09726.4 CDI87277.1 - 0.82 7.8 75.2 0.0037 15.6 42.5 2.1 2 0 0 2 2 2 0 Transmembrane protein MIP-T3 PF10243.4 CDI87278.1 - 1.3e-05 23.9 85.6 0.00031 19.3 10.9 2.2 2 0 0 2 2 2 2 Microtubule-binding protein MIP-T3 DUF4604 PF15377.1 CDI87278.1 - 1.3e-05 25.4 0.0 1.3e-05 25.4 0.0 4.3 2 2 2 4 4 4 1 Domain of unknown function (DUF4604) Claudin_2 PF13903.1 CDI87278.1 - 0.0069 16.0 7.5 0.0069 16.0 5.2 7.1 3 2 1 6 6 6 1 PMP-22/EMP/MP20/Claudin tight junction PLRV_ORF5 PF01690.12 CDI87278.1 - 0.91 8.5 66.9 0.18 10.9 9.7 2.5 2 0 0 2 2 2 0 Potato leaf roll virus readthrough protein ETRAMP PF09716.5 CDI87279.1 - 0.02 14.8 0.4 0.53 10.2 0.0 3.5 3 3 0 3 3 3 0 Malarial early transcribed membrane protein (ETRAMP) SR-25 PF10500.4 CDI87280.1 - 0.0054 16.2 7.6 0.0054 16.2 5.2 3.4 3 1 0 3 3 3 2 Nuclear RNA-splicing-associated protein Ribosomal_60s PF00428.14 CDI87280.1 - 0.13 12.6 4.7 2 8.8 0.6 2.3 2 0 0 2 2 2 0 60s Acidic ribosomal protein ETRAMP PF09716.5 CDI87280.1 - 0.44 10.5 12.7 13 5.8 8.8 3.0 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) DUF2867 PF11066.3 CDI87280.1 - 0.5 10.0 3.5 1.7 8.3 2.4 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2867) Oleosin PF01277.12 CDI87280.1 - 0.54 9.8 0.0 0.54 9.8 0.0 3.4 3 1 1 4 4 4 0 Oleosin TRA-1_regulated PF02343.11 CDI87280.1 - 0.98 8.9 10.2 0.11 12.0 0.3 2.5 3 0 0 3 3 3 0 TRA-1 regulated protein R03H10.4 Spore_YhcN_YlaJ PF09580.5 CDI87280.1 - 1.2 9.2 21.1 2.2 8.3 8.8 2.3 2 0 0 2 2 2 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) DUF912 PF06024.7 CDI87280.1 - 5 7.2 19.2 0.18 11.8 4.2 3.3 3 1 1 4 4 4 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF367 PF04034.8 CDI87282.1 - 2.3e-23 82.2 0.0 1.1e-22 79.9 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF367) RLI PF04068.10 CDI87282.1 - 0.00032 20.1 0.0 0.00061 19.3 0.0 1.5 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI DUF755 PF05501.6 CDI87284.1 - 0.00031 20.8 25.5 0.00031 20.8 17.7 14.8 14 1 1 15 15 15 3 Domain of unknown function (DUF755) Chorion_2 PF03964.10 CDI87285.1 - 0.0024 18.3 10.3 0.19 12.3 0.5 2.1 2 0 0 2 2 2 2 Chorion family 2 Ribosomal_60s PF00428.14 CDI87285.1 - 0.017 15.4 25.5 0.056 13.8 4.8 2.1 2 0 0 2 2 2 0 60s Acidic ribosomal protein DUF1777 PF08648.7 CDI87285.1 - 0.34 10.6 14.1 0.46 10.1 9.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) MerE PF05052.7 CDI87286.1 - 0.014 15.3 0.7 0.21 11.5 0.5 2.2 1 1 0 1 1 1 0 MerE protein Penicil_amidase PF01804.13 CDI87287.1 - 4.4e-76 257.4 0.0 1.8e-69 235.6 0.0 2.1 2 0 0 2 2 2 2 Penicillin amidase DUF667 PF05018.8 CDI87288.1 - 2.2e-42 144.4 0.0 3.9e-42 143.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF667) LepA_C PF06421.7 CDI87288.1 - 7.2e-41 138.4 0.2 7.2e-41 138.4 0.1 1.7 2 0 0 2 2 2 1 GTP-binding protein LepA C-terminus GTP_EFTU PF00009.22 CDI87288.1 - 4.1e-10 39.4 0.0 4.4e-06 26.2 0.0 2.3 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain EFG_C PF00679.19 CDI87288.1 - 0.021 14.6 0.0 0.043 13.6 0.0 1.5 1 0 0 1 1 1 0 Elongation factor G C-terminus EFG_II PF14492.1 CDI87288.1 - 0.037 13.8 0.1 0.46 10.3 0.1 2.4 1 1 0 1 1 1 0 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.20 CDI87288.1 - 0.063 13.3 0.4 3 8.0 0.1 2.8 2 0 0 2 2 2 0 Elongation factor Tu domain 2 T2SM PF04612.7 CDI87289.1 - 0.00025 20.8 0.9 0.00055 19.7 0.6 1.5 1 0 0 1 1 1 1 Type II secretion system (T2SS), protein M RNase_P_Rpp14 PF01900.14 CDI87289.1 - 0.0088 15.9 0.0 0.012 15.5 0.0 1.2 1 0 0 1 1 1 1 Rpp14/Pop5 family DUF4414 PF14377.1 CDI87289.1 - 0.016 15.0 1.6 0.029 14.3 1.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4414) Ferric_reduct PF01794.14 CDI87289.1 - 0.057 13.4 0.5 0.091 12.8 0.4 1.5 1 1 0 1 1 1 0 Ferric reductase like transmembrane component EcsC PF12787.2 CDI87289.1 - 7.3 5.9 7.4 1.4 8.2 2.3 1.7 2 0 0 2 2 2 0 EcsC protein family Sec63 PF02889.11 CDI87290.1 - 1.6e-157 523.6 0.1 3.4e-99 332.0 0.0 3.4 2 1 1 3 3 3 3 Sec63 Brl domain DEAD PF00270.24 CDI87290.1 - 7.5e-47 158.9 0.9 4.5e-27 94.5 0.1 3.4 4 0 0 4 4 4 2 DEAD/DEAH box helicase Helicase_C PF00271.26 CDI87290.1 - 8.8e-12 44.7 0.0 3.3e-08 33.2 0.0 2.8 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.10 CDI87290.1 - 8.2e-09 35.5 0.0 5.3e-08 32.9 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Pkinase_Tyr PF07714.12 CDI87291.1 - 0.00034 19.7 0.0 0.00063 18.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 CDI87291.1 - 0.0017 17.5 0.0 0.0028 16.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain WASH_WAHD PF11945.3 CDI87293.1 - 0.0025 17.1 0.9 0.0025 17.1 0.6 1.7 2 0 0 2 2 2 1 WAHD domain of WASH complex Bindin PF02084.10 CDI87293.1 - 0.074 13.0 1.7 0.45 10.5 0.4 2.1 2 0 0 2 2 2 0 Bindin DUF3682 PF12446.3 CDI87295.1 - 0.008 16.4 26.8 0.008 16.4 18.6 11.7 8 2 3 11 11 11 1 Protein of unknown function (DUF3682) zf-DHHC PF01529.15 CDI87295.1 - 0.1 11.9 6.4 1.8 7.9 0.9 2.9 2 0 0 2 2 2 0 DHHC palmitoyltransferase Secretin_N_2 PF07655.8 CDI87297.1 - 6.1 7.3 18.9 0.79 10.1 9.5 2.1 2 0 0 2 2 2 0 Secretin N-terminal domain IncA PF04156.9 CDI87298.1 - 0.00057 19.5 7.2 0.00066 19.3 5.0 1.1 1 0 0 1 1 1 1 IncA protein Ribosomal_60s PF00428.14 CDI87298.1 - 0.0038 17.5 2.3 0.0049 17.2 1.6 1.2 1 0 0 1 1 1 1 60s Acidic ribosomal protein DUF2029 PF09594.5 CDI87298.1 - 0.014 14.8 0.0 0.015 14.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2029) OATP PF03137.15 CDI87298.1 - 0.052 11.6 1.0 0.06 11.3 0.7 1.0 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family DUF2217 PF10265.4 CDI87298.1 - 0.26 10.0 3.9 0.29 9.8 2.7 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) FliP PF00813.15 CDI87298.1 - 0.29 10.8 1.5 0.35 10.5 1.0 1.1 1 0 0 1 1 1 0 FliP family DUF1980 PF09323.5 CDI87298.1 - 0.43 10.3 1.8 0.45 10.2 1.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) DUF3123 PF11321.3 CDI87298.1 - 0.48 10.7 3.0 0.64 10.3 2.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3123) DUF3824 PF12868.2 CDI87298.1 - 0.73 10.7 8.6 0.94 10.4 6.0 1.1 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) Spt20 PF12090.3 CDI87298.1 - 0.96 8.7 6.2 1 8.6 4.3 1.2 1 0 0 1 1 1 0 Spt20 family DUF3710 PF12502.3 CDI87298.1 - 1.2 8.3 8.6 1.4 8.1 6.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3710) RAB3GAP2_N PF14655.1 CDI87298.1 - 5.2 5.9 11.0 6.3 5.6 7.6 1.1 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus FimP PF09766.4 CDI87298.1 - 5.7 5.9 16.9 6.5 5.7 11.7 1.1 1 0 0 1 1 1 0 Fms-interacting protein CRT-like PF08627.5 CDI87299.1 - 0.12 12.3 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 CRT-like Activator_LAG-3 PF11498.3 CDI87302.1 - 0.00011 21.1 25.6 0.00011 21.1 17.8 7.6 5 2 1 6 6 6 2 Transcriptional activator LAG-3 TMEM51 PF15345.1 CDI87302.1 - 0.0054 16.4 6.0 0.0054 16.4 4.1 9.3 1 1 3 7 7 7 1 Transmembrane protein 51 AAA_15 PF13175.1 CDI87302.1 - 0.85 8.5 6.9 1.6 7.7 4.8 1.3 1 0 0 1 1 1 0 AAA ATPase domain FimP PF09766.4 CDI87303.1 - 0.88 8.5 38.3 0.42 9.6 3.1 2.6 3 0 0 3 3 3 0 Fms-interacting protein Pex16 PF08610.5 CDI87303.1 - 3.8 6.4 13.5 0.6 9.0 3.8 2.5 2 0 0 2 2 2 0 Peroxisomal membrane protein (Pex16) RMP PF14996.1 CDI87303.1 - 8.7 6.2 15.7 11 5.9 0.2 3.0 3 0 0 3 3 3 0 Retinal Maintenance Coprogen_oxidas PF01218.13 CDI87305.1 - 9.2e-11 40.8 7.5 9.2e-11 40.8 5.2 3.9 2 1 2 4 4 3 1 Coproporphyrinogen III oxidase MIP-T3 PF10243.4 CDI87305.1 - 2.1e-05 23.2 48.9 2.1e-05 23.2 33.9 2.2 2 0 0 2 2 2 1 Microtubule-binding protein MIP-T3 Activator_LAG-3 PF11498.3 CDI87305.1 - 0.00028 19.7 41.1 0.00028 19.7 28.5 4.2 2 1 1 3 3 1 1 Transcriptional activator LAG-3 Spore_coat_CotO PF14153.1 CDI87305.1 - 0.00031 20.2 75.1 0.0015 18.0 19.7 3.2 3 0 0 3 3 3 2 Spore coat protein CotO Caldesmon PF02029.10 CDI87305.1 - 0.0028 16.1 5.0 0.0028 16.1 3.5 3.0 3 0 0 3 3 3 1 Caldesmon DUF1510 PF07423.6 CDI87305.1 - 0.0067 15.8 11.9 0.0067 15.8 8.2 3.1 3 0 0 3 3 3 2 Protein of unknown function (DUF1510) FAM60A PF15396.1 CDI87305.1 - 0.06 13.0 47.2 0.3 10.7 13.4 3.2 3 0 0 3 3 3 0 Protein Family FAM60A PAT1 PF09770.4 CDI87305.1 - 0.14 10.4 141.2 0.02 13.1 28.0 2.2 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 PIH1 PF08190.7 CDI87305.1 - 0.18 11.2 66.3 0.31 10.4 11.4 3.3 3 0 0 3 3 3 0 pre-RNA processing PIH1/Nop17 CDC45 PF02724.9 CDI87305.1 - 0.22 9.4 49.6 0.028 12.4 4.2 3.1 3 0 0 3 3 3 0 CDC45-like protein DUF3487 PF11990.3 CDI87305.1 - 0.23 10.8 1.0 0.57 9.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3487) RR_TM4-6 PF06459.7 CDI87305.1 - 1.2 8.9 61.8 0.047 13.5 13.6 3.2 3 0 0 3 3 3 0 Ryanodine Receptor TM 4-6 Cwf_Cwc_15 PF04889.7 CDI87305.1 - 2.1 7.9 57.0 1.5 8.4 8.1 3.2 3 0 0 3 3 3 0 Cwf15/Cwc15 cell cycle control protein DUF2052 PF09747.4 CDI87305.1 - 4.2 7.2 73.1 2.5 7.9 13.2 3.1 3 0 0 3 3 3 0 Coiled-coil domain containing protein (DUF2052) SAPS PF04499.10 CDI87305.1 - 4.8 5.7 46.2 1.1 7.8 6.3 3.0 3 0 0 3 3 3 0 SIT4 phosphatase-associated protein Band_3_cyto PF07565.8 CDI87305.1 - 5 6.5 66.5 0.59 9.5 10.5 3.2 3 0 0 3 3 3 0 Band 3 cytoplasmic domain Vfa1 PF08432.5 CDI87305.1 - 8.3 6.3 60.6 2 8.4 10.2 3.2 3 0 0 3 3 3 0 AAA-ATPase Vps4-associated protein 1 SR-25 PF10500.4 CDI87306.1 - 0.0014 18.1 24.2 0.0018 17.7 16.8 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein NPR3 PF03666.8 CDI87306.1 - 0.06 11.8 20.6 0.087 11.3 14.3 1.3 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Ribosomal_60s PF00428.14 CDI87306.1 - 0.15 12.4 2.0 0.22 11.9 1.4 1.3 1 0 0 1 1 1 0 60s Acidic ribosomal protein PBP1_TM PF14812.1 CDI87306.1 - 1.1 9.6 11.1 0.27 11.5 2.4 2.2 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CAF-1_p150 PF11600.3 CDI87306.1 - 1.2 8.4 32.7 1.8 7.9 22.6 1.3 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF572 PF04502.8 CDI87306.1 - 1.7 7.7 28.2 2 7.5 19.5 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF572) Peptidase_S64 PF08192.6 CDI87306.1 - 5.8 5.1 24.0 6.8 4.8 16.6 1.0 1 0 0 1 1 1 0 Peptidase family S64 GAGA_bind PF06217.7 CDI87306.1 - 7.6 6.3 25.4 11 5.9 17.6 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family Presenilin PF01080.12 CDI87306.1 - 8 5.1 23.9 9.9 4.8 16.6 1.1 1 0 0 1 1 1 0 Presenilin SR-25 PF10500.4 CDI87307.1 - 0.037 13.5 7.0 0.035 13.5 4.9 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF1635 PF07795.6 CDI87307.1 - 0.38 10.0 4.5 0.38 10.1 3.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) Apc15p PF05841.6 CDI87307.1 - 2.8 8.7 11.0 3 8.6 7.7 1.1 1 0 0 1 1 1 0 Apc15p protein CAF-1_p150 PF11600.3 CDI87307.1 - 4.6 6.5 8.0 5.2 6.3 5.6 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal UPF0560 PF10577.4 CDI87307.1 - 5.2 5.1 8.9 5.4 5.1 6.2 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Pex14_N PF04695.8 CDI87307.1 - 5.9 6.9 13.6 7 6.7 9.5 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region APC_CDC26 PF10471.4 CDI87307.1 - 8.3 7.2 12.7 10 6.9 8.7 1.3 1 1 0 1 1 1 0 Anaphase-promoting complex APC subunit 1 Med15 PF09606.5 CDI87308.1 - 0.02 13.1 46.2 0.022 12.9 32.0 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal MIP-T3 PF10243.4 CDI87308.1 - 0.034 12.6 40.9 0.041 12.3 28.4 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DDRGK PF09756.4 CDI87308.1 - 4.4 6.6 18.8 0.13 11.6 8.2 1.8 2 0 0 2 2 2 0 DDRGK domain DUF572 PF04502.8 CDI87308.1 - 5.8 6.0 46.4 8.9 5.4 32.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) Spt20 PF12090.3 CDI87309.1 - 0.021 14.1 0.9 0.021 14.1 0.6 2.4 2 1 0 2 2 2 0 Spt20 family Ctr PF04145.10 CDI87309.1 - 3 7.8 12.8 6.2 6.8 1.7 3.2 2 1 1 3 3 3 0 Ctr copper transporter family DUF106 PF01956.11 CDI87309.1 - 5.8 6.4 6.7 21 4.5 0.2 2.2 2 0 0 2 2 2 0 Integral membrane protein DUF106 Ham1p_like PF01725.11 CDI87310.1 - 8.3e-15 54.6 1.3 9.8e-15 54.4 0.9 1.1 1 0 0 1 1 1 1 Ham1 family Spore_coat_CotO PF14153.1 CDI87310.1 - 1.3e-05 24.7 7.1 1.6e-05 24.4 4.9 1.1 1 0 0 1 1 1 1 Spore coat protein CotO DUF3043 PF11241.3 CDI87310.1 - 0.013 15.1 1.6 0.013 15.1 1.1 1.4 2 0 0 2 2 1 0 Protein of unknown function (DUF3043) DUF4407 PF14362.1 CDI87310.1 - 0.034 13.1 6.8 0.032 13.1 4.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Band_3_cyto PF07565.8 CDI87310.1 - 0.041 13.4 2.7 0.038 13.4 1.9 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain MmlI PF09448.5 CDI87310.1 - 0.045 13.5 0.0 0.053 13.2 0.0 1.1 1 0 0 1 1 1 0 Methylmuconolactone methyl-isomerase SPX PF03105.14 CDI87310.1 - 0.067 12.9 4.4 0.08 12.7 3.1 1.0 1 0 0 1 1 1 0 SPX domain BAF1_ABF1 PF04684.8 CDI87310.1 - 0.067 12.0 22.7 0.076 11.8 15.7 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor DUF1178 PF06676.6 CDI87310.1 - 0.073 13.2 6.1 1.8 8.7 3.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1178) XRN_N PF03159.13 CDI87310.1 - 0.13 11.5 3.0 0.15 11.4 2.1 1.2 1 0 0 1 1 1 0 XRN 5'-3' exonuclease N-terminus DDRGK PF09756.4 CDI87310.1 - 0.19 11.1 12.7 0.059 12.7 6.9 1.5 2 0 0 2 2 2 0 DDRGK domain FimP PF09766.4 CDI87310.1 - 0.2 10.6 19.9 0.29 10.1 13.8 1.1 1 0 0 1 1 1 0 Fms-interacting protein DUF2126 PF09899.4 CDI87310.1 - 0.28 9.1 6.2 0.36 8.8 4.3 1.1 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) Ycf1 PF05758.7 CDI87310.1 - 0.32 8.6 4.9 0.32 8.6 3.4 1.0 1 0 0 1 1 1 0 Ycf1 FHIPEP PF00771.15 CDI87310.1 - 0.39 8.9 2.7 0.37 9.0 1.9 1.1 1 0 0 1 1 1 0 FHIPEP family DHHW PF14286.1 CDI87310.1 - 0.4 9.9 3.6 0.52 9.5 2.5 1.1 1 0 0 1 1 1 0 DHHW protein Neur_chan_memb PF02932.11 CDI87310.1 - 0.54 10.0 2.4 0.65 9.8 1.7 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Suf PF05843.9 CDI87310.1 - 1.1 8.9 15.7 1.6 8.3 10.9 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Topoisom_I_N PF02919.10 CDI87310.1 - 1.2 8.4 6.4 0.19 11.0 1.9 1.5 2 0 0 2 2 2 0 Eukaryotic DNA topoisomerase I, DNA binding fragment Peptidase_S49_N PF08496.5 CDI87310.1 - 1.2 8.8 9.5 0.3 10.8 4.5 1.4 2 0 0 2 2 1 0 Peptidase family S49 N-terminal Glyco_transf_15 PF01793.11 CDI87310.1 - 1.4 7.7 7.1 2 7.2 4.9 1.2 1 0 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase DUF912 PF06024.7 CDI87310.1 - 1.6 8.8 5.6 3 7.9 3.9 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) eIF-3_zeta PF05091.7 CDI87310.1 - 1.9 6.9 12.1 2.5 6.6 8.4 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) WASH-7_C PF14746.1 CDI87310.1 - 2.4 7.7 7.2 4.3 6.8 5.0 1.5 1 0 0 1 1 1 0 WASH complex subunit 7, C-terminal Med15 PF09606.5 CDI87310.1 - 2.4 6.2 31.3 2.9 5.9 21.7 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal FCP1_C PF09309.5 CDI87310.1 - 5.9 6.1 11.7 10 5.3 8.1 1.4 1 0 0 1 1 1 0 FCP1, C-terminal CagX PF03524.10 CDI87310.1 - 6.3 6.0 9.3 8.8 5.5 6.4 1.2 1 0 0 1 1 1 0 Conjugal transfer protein Serinc PF03348.10 CDI87310.1 - 6.4 5.3 10.0 8 5.0 6.9 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) DUF4175 PF13779.1 CDI87310.1 - 7 4.2 31.3 2.1 5.9 19.2 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4175) Hid1 PF12722.2 CDI87310.1 - 7.7 4.0 8.4 9.4 3.7 5.8 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF3464 PF11947.3 CDI87310.1 - 8.1 5.8 8.1 14 5.1 5.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) Fungal_trans_2 PF11951.3 CDI87310.1 - 8.2 4.9 8.9 6.9 5.1 5.1 1.5 1 1 0 2 2 2 0 Fungal specific transcription factor domain Baculo_PP31 PF05311.6 CDI87310.1 - 8.9 5.4 12.0 13 4.9 8.4 1.2 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) Folate_carrier PF01770.13 CDI87310.1 - 9.5 4.6 6.0 13 4.1 4.2 1.2 1 0 0 1 1 1 0 Reduced folate carrier Conotoxin PF02950.12 CDI87310.1 - 10 7.0 6.5 22 5.9 4.5 1.6 1 0 0 1 1 1 0 Conotoxin SR-25 PF10500.4 CDI87311.1 - 0.0015 18.0 8.4 0.0015 18.0 5.8 5.0 3 1 1 4 4 4 1 Nuclear RNA-splicing-associated protein Secretin_N_2 PF07655.8 CDI87311.1 - 1.2 9.5 41.0 0.43 11.0 0.9 3.7 3 0 0 3 3 3 0 Secretin N-terminal domain SOBP PF15279.1 CDI87311.1 - 3.3 8.0 23.3 2.9 8.2 2.6 3.1 3 0 0 3 3 3 0 Sine oculis-binding protein UreE_N PF02814.10 CDI87313.1 - 0.12 11.9 1.0 0.48 9.9 0.7 2.0 1 0 0 1 1 1 0 UreE urease accessory protein, N-terminal domain Spt20 PF12090.3 CDI87313.1 - 0.23 10.7 18.4 0.37 10.1 1.9 2.3 2 0 0 2 2 2 0 Spt20 family AAA_23 PF13476.1 CDI87313.1 - 0.25 11.6 13.9 0.73 10.1 1.2 2.3 2 0 0 2 2 2 0 AAA domain UPF0560 PF10577.4 CDI87313.1 - 2.3 6.3 34.3 2 6.5 6.7 2.3 2 0 0 2 2 2 0 Uncharacterised protein family UPF0560 SPX PF03105.14 CDI87313.1 - 7.1 6.3 19.2 3 7.5 4.3 2.2 2 0 0 2 2 2 0 SPX domain FimP PF09766.4 CDI87313.1 - 8.4 5.3 33.3 5.3 6.0 7.5 2.4 2 0 0 2 2 2 0 Fms-interacting protein CAF-1_p150 PF11600.3 CDI87314.1 - 0.0052 16.1 41.7 0.0052 16.1 28.9 5.1 6 0 0 6 6 6 2 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF1510 PF07423.6 CDI87314.1 - 0.13 11.6 48.9 1 8.6 22.4 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) SIR2 PF02146.12 CDI87315.1 - 1.1e-09 38.3 6.1 5e-05 23.0 0.0 4.2 2 1 1 3 3 3 3 Sir2 family Peptidase_A24 PF01478.13 CDI87316.1 - 6.6 6.9 8.4 9.9 6.3 5.8 1.3 1 0 0 1 1 1 0 Type IV leader peptidase family UCH PF00443.24 CDI87318.1 - 5.1e-16 58.5 0.0 7.2e-16 58.1 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CDI87318.1 - 0.14 11.5 0.0 0.26 10.6 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase TPR_12 PF13424.1 CDI87319.1 - 1.4e-06 28.1 1.6 1.4e-06 28.1 1.1 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 CDI87319.1 - 0.0025 17.4 4.8 7 6.6 0.0 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat Apc3 PF12895.2 CDI87319.1 - 0.018 15.2 1.4 0.091 12.9 1.0 2.3 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 ATP-cone PF03477.11 CDI87319.1 - 0.023 15.1 3.9 0.53 10.7 0.0 3.5 3 1 1 4 4 4 0 ATP cone domain TPR_4 PF07721.9 CDI87319.1 - 0.054 13.9 0.5 22 5.8 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.1 CDI87319.1 - 0.23 11.8 9.0 0.26 11.6 0.1 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.1 CDI87319.1 - 0.28 11.9 9.7 0.41 11.3 0.2 4.1 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.1 CDI87319.1 - 4 7.1 13.7 0.27 10.9 2.5 3.4 3 1 0 3 3 3 0 TPR repeat YccV-like PF08755.6 CDI87320.1 - 3.6e-21 74.9 0.0 6.1e-21 74.2 0.0 1.3 1 0 0 1 1 1 1 Hemimethylated DNA-binding protein YccV like PRKCSH PF07915.8 CDI87320.1 - 3.8e-11 43.6 0.0 5.9e-05 23.7 0.0 3.1 2 1 0 2 2 2 2 Glucosidase II beta subunit-like protein PRKCSH_1 PF13015.1 CDI87320.1 - 0.0028 17.1 0.0 0.52 9.7 0.0 2.4 2 0 0 2 2 2 2 Glucosidase II beta subunit-like protein MNNL PF07657.8 CDI87320.1 - 0.16 11.9 0.1 0.32 10.9 0.1 1.4 1 0 0 1 1 1 0 N terminus of Notch ligand Fusion_gly PF00523.13 CDI87321.1 - 0.2 9.7 1.8 0.24 9.4 0.0 1.8 2 0 0 2 2 2 0 Fusion glycoprotein F0 UvrD-helicase PF00580.16 CDI87322.1 - 9e-48 163.1 0.0 1.4e-43 149.4 0.0 2.2 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain UvrD_C PF13361.1 CDI87322.1 - 8e-41 140.6 0.2 8.3e-20 71.5 0.0 3.9 4 0 0 4 4 4 3 UvrD-like helicase C-terminal domain AAA_19 PF13245.1 CDI87322.1 - 1.3e-07 31.2 1.0 4.2e-07 29.6 0.1 2.4 2 0 0 2 2 2 1 Part of AAA domain UvrD_C_2 PF13538.1 CDI87322.1 - 1.4e-07 31.5 6.6 0.00036 20.6 0.0 3.6 3 0 0 3 3 3 2 UvrD-like helicase C-terminal domain Macoilin PF09726.4 CDI87322.1 - 0.87 7.7 13.1 1.4 7.1 9.1 1.2 1 0 0 1 1 1 0 Transmembrane protein Ycf1 PF05758.7 CDI87322.1 - 2.1 5.9 12.3 2.9 5.4 8.6 1.1 1 0 0 1 1 1 0 Ycf1 CDC45 PF02724.9 CDI87322.1 - 3.4 5.6 12.9 4.9 5.0 9.0 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF4175 PF13779.1 CDI87322.1 - 7.8 4.0 35.6 12 3.4 24.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) DHO_dh PF01180.16 CDI87323.1 - 1.6e-74 250.5 0.1 1.2e-69 234.4 0.0 2.2 1 1 1 2 2 2 2 Dihydroorotate dehydrogenase FMN_dh PF01070.13 CDI87323.1 - 0.012 14.4 0.3 0.029 13.1 0.2 1.6 1 1 0 1 1 1 0 FMN-dependent dehydrogenase WEMBL PF05701.6 CDI87323.1 - 0.014 13.8 1.9 0.021 13.2 1.3 1.1 1 0 0 1 1 1 0 Weak chloroplast movement under blue light PcrB PF01884.12 CDI87323.1 - 0.069 12.3 0.1 2.1 7.5 0.0 2.2 2 0 0 2 2 2 0 PcrB family DUF1323 PF07037.6 CDI87323.1 - 0.094 12.8 0.2 15 5.8 0.1 2.4 1 1 1 2 2 2 0 Putative transcription regulator (DUF1323) HSD3 PF15244.1 CDI87326.1 - 2.4 7.3 32.0 2.7 7.1 22.2 1.1 1 0 0 1 1 1 0 Hydroxy-steroid dehydrogenase RAP1 PF07218.6 CDI87326.1 - 3.9 5.4 20.0 4.8 5.1 13.8 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Spt20 PF12090.3 CDI87327.1 - 0.39 10.0 3.3 4.8 6.4 0.0 2.9 3 0 0 3 3 3 0 Spt20 family UPF0564 PF10595.4 CDI87328.1 - 0.0039 16.1 34.3 0.0039 16.1 23.7 5.7 4 1 1 5 5 5 1 Uncharacterised protein family UPF0564 IncA PF04156.9 CDI87329.1 - 0.0059 16.2 34.3 0.0059 16.2 23.8 4.1 1 1 3 4 4 4 1 IncA protein Kelch_3 PF13415.1 CDI87330.1 - 1.6e-25 88.6 10.4 1.9e-11 43.7 0.7 5.3 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_4 PF13418.1 CDI87330.1 - 3e-21 74.9 13.2 6.5e-06 25.8 0.0 4.6 4 1 0 4 4 4 4 Galactose oxidase, central domain Kelch_5 PF13854.1 CDI87330.1 - 8.6e-21 73.4 4.2 2.4e-05 24.1 0.6 4.8 5 0 0 5 5 5 3 Kelch motif Kelch_6 PF13964.1 CDI87330.1 - 2.6e-15 55.8 14.3 1.8e-06 27.8 0.4 5.1 2 1 3 5 5 5 4 Kelch motif Kelch_2 PF07646.10 CDI87330.1 - 7.7e-13 47.6 15.7 0.00089 18.9 0.5 4.8 4 0 0 4 4 4 4 Kelch motif Kelch_1 PF01344.20 CDI87330.1 - 1.1e-09 37.6 9.8 0.0051 16.3 0.1 5.7 5 1 0 5 5 5 3 Kelch motif Prefoldin_2 PF01920.15 CDI87330.1 - 0.0063 16.2 1.0 0.011 15.4 0.7 1.4 1 0 0 1 1 1 1 Prefoldin subunit DUF601 PF04642.7 CDI87330.1 - 0.034 13.5 0.5 0.049 13.0 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function, DUF601 DUF3472 PF11958.3 CDI87330.1 - 0.035 14.4 0.1 5.3 7.3 0.0 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF3472) Fzo_mitofusin PF04799.8 CDI87330.1 - 0.14 11.5 0.1 0.21 10.9 0.1 1.2 1 0 0 1 1 1 0 fzo-like conserved region DUF3602 PF12223.3 CDI87330.1 - 0.15 12.5 1.0 29 5.1 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3602) Cep57_CLD_2 PF14197.1 CDI87330.1 - 0.23 11.4 1.8 3.4 7.6 0.2 2.6 1 1 1 2 2 2 0 Centrosome localisation domain of PPC89 E2F_TDP PF02319.15 CDI87331.1 - 0.00058 19.3 0.0 0.057 13.0 0.0 2.3 2 0 0 2 2 2 1 E2F/DP family winged-helix DNA-binding domain adh_short PF00106.20 CDI87331.1 - 0.027 14.3 0.2 0.077 12.9 0.0 1.8 2 0 0 2 2 2 0 short chain dehydrogenase adh_short_C2 PF13561.1 CDI87331.1 - 0.068 12.9 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase Phi_1 PF04674.7 CDI87331.1 - 0.087 11.9 0.0 0.098 11.8 0.0 1.2 1 0 0 1 1 1 0 Phosphate-induced protein 1 conserved region TGT_C1 PF14809.1 CDI87331.1 - 0.3 10.9 1.0 25 4.8 0.1 2.5 1 1 1 2 2 2 0 C1 domain of tRNA-guanine transglycosylase dimerisation IncA PF04156.9 CDI87332.1 - 0.00018 21.1 22.1 0.00018 21.1 15.3 3.0 1 1 1 2 2 1 1 IncA protein BPD_transp_2 PF02653.11 CDI87332.1 - 0.0039 16.2 0.0 0.047 12.6 0.0 2.1 2 0 0 2 2 2 1 Branched-chain amino acid transport system / permease component PAT1 PF09770.4 CDI87332.1 - 0.011 13.9 88.9 0.013 13.7 61.6 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 RIC3 PF15361.1 CDI87332.1 - 0.022 14.9 8.4 0.022 14.9 5.8 3.4 2 1 2 4 4 4 0 Resistance to inhibitors of cholinesterase homologue 3 DUF4010 PF13194.1 CDI87332.1 - 0.062 12.5 3.6 0.074 12.3 0.1 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4010) ODV-E18 PF10717.4 CDI87332.1 - 0.15 11.4 0.8 0.47 9.9 0.0 2.2 3 0 0 3 3 3 0 Occlusion-derived virus envelope protein ODV-E18 RNF111_N PF15303.1 CDI87332.1 - 2.1 7.8 32.2 3.5 7.0 22.3 1.3 1 0 0 1 1 1 0 E3 ubiquitin-protein ligase Arkadia N-terminus YjgP_YjgQ PF03739.9 CDI87332.1 - 2.8 6.5 26.4 1.3e+02 1.1 18.3 2.1 1 1 0 1 1 1 0 Predicted permease YjgP/YjgQ family DUF572 PF04502.8 CDI87332.1 - 3.1 6.9 40.8 4.7 6.3 28.3 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) TRAP_alpha PF03896.11 CDI87332.1 - 3.2 6.6 18.8 0.022 13.7 5.7 2.3 1 1 2 3 3 3 0 Translocon-associated protein (TRAP), alpha subunit CECR6_TMEM121 PF14997.1 CDI87332.1 - 4.1 6.9 6.3 0.46 10.0 0.1 2.4 3 0 0 3 3 3 0 CECR6/TMEM121 family TAP42 PF04177.7 CDI87333.1 - 0.0013 17.8 0.5 0.0018 17.2 0.2 1.4 1 1 0 1 1 1 1 TAP42-like family Cwf_Cwc_15 PF04889.7 CDI87333.1 - 0.31 10.7 2.6 0.43 10.2 1.8 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Telomere_Sde2 PF13019.1 CDI87333.1 - 0.8 9.3 3.9 1.1 8.9 2.7 1.2 1 0 0 1 1 1 0 Telomere stability and silencing Macoilin PF09726.4 CDI87333.1 - 1.7 6.8 6.8 2 6.6 4.7 1.1 1 0 0 1 1 1 0 Transmembrane protein Rtf2 PF04641.7 CDI87334.1 - 7.9 5.5 30.4 8.4 5.5 21.1 1.0 1 0 0 1 1 1 0 Rtf2 RING-finger Ribosomal_60s PF00428.14 CDI87335.1 - 0.0068 16.7 6.6 0.0068 16.7 4.5 5.7 4 2 1 5 5 5 1 60s Acidic ribosomal protein Albumin_I PF08027.6 CDI87335.1 - 0.14 11.8 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 Albumin I DUF2029 PF09594.5 CDI87335.1 - 0.2 11.1 8.1 0.68 9.3 5.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2029) Trp_oprn_chp PF09534.5 CDI87335.1 - 2 8.0 19.8 2.5 7.6 12.2 2.1 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) SAGA-Tad1 PF12767.2 CDI87335.1 - 2 8.0 25.0 0.046 13.3 8.8 2.4 2 1 0 2 2 2 0 Transcriptional regulator of RNA polII, SAGA, subunit DUF2076 PF09849.4 CDI87335.1 - 2.1 8.3 34.9 1.5 8.8 21.9 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2076) PAT1 PF09770.4 CDI87335.1 - 5 5.2 59.6 0.52 8.4 28.9 2.0 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 GTP_EFTU PF00009.22 CDI87336.1 - 8.9e-20 70.9 0.0 1.1e-19 70.6 0.0 1.0 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Exonuc_VII_L PF02601.10 CDI87338.1 - 0.013 14.7 28.6 0.024 13.8 19.8 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit SOBP PF15279.1 CDI87338.1 - 1.5 9.1 20.7 1.7 8.9 14.4 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein DUF2839 PF10999.3 CDI87339.1 - 0.094 12.7 0.2 0.094 12.7 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2839) DUF3801 PF12687.2 CDI87343.1 - 0.0059 16.1 16.7 0.0059 16.1 11.6 5.7 3 2 1 4 4 4 1 Protein of unknown function (DUF3801) 7TM_GPCR_Srw PF10324.4 CDI87343.1 - 0.45 9.5 9.2 0.044 12.9 0.4 2.4 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srw DUF1664 PF07889.7 CDI87345.1 - 0.39 10.5 3.0 0.48 10.2 0.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) IL4 PF00727.13 CDI87347.1 - 0.14 12.0 0.4 4.1 7.2 0.1 2.3 2 0 0 2 2 2 0 Interleukin 4 Syntaxin-6_N PF09177.6 CDI87347.1 - 0.34 11.3 1.7 1.6 9.1 0.1 2.6 2 2 1 3 3 3 0 Syntaxin 6, N-terminal AATF-Che1 PF13339.1 CDI87347.1 - 2.1 8.4 5.0 1.9 8.6 0.8 2.3 1 1 1 2 2 2 0 Apoptosis antagonizing transcription factor RabGAP-TBC PF00566.13 CDI87349.1 - 3.6e-05 23.3 0.1 3.6e-05 23.3 0.0 2.1 2 0 0 2 2 2 1 Rab-GTPase-TBC domain DUF1713 PF08213.6 CDI87350.1 - 0.5 10.0 2.5 0.69 9.5 1.8 1.2 1 0 0 1 1 1 0 Mitochondrial domain of unknown function (DUF1713) Nop14 PF04147.7 CDI87350.1 - 0.89 7.3 12.8 1 7.1 8.8 1.0 1 0 0 1 1 1 0 Nop14-like family U1snRNP70_N PF12220.3 CDI87351.1 - 0.12 12.6 11.0 0.14 12.4 7.6 1.1 1 0 0 1 1 1 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal CTF_NFI PF00859.13 CDI87351.1 - 0.22 11.2 5.9 0.23 11.2 4.1 1.1 1 0 0 1 1 1 0 CTF/NF-I family transcription modulation region AAA_23 PF13476.1 CDI87351.1 - 0.24 11.6 10.4 0.26 11.5 7.2 1.0 1 0 0 1 1 1 0 AAA domain eIF3_subunit PF08597.5 CDI87351.1 - 0.79 9.2 9.5 0.89 9.0 6.6 1.0 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit CAF-1_p150 PF11600.3 CDI87351.1 - 1.4 8.2 16.4 1.7 7.9 11.3 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal SprA-related PF12118.3 CDI87351.1 - 1.9 7.7 23.6 2.1 7.5 16.4 1.1 1 0 0 1 1 1 0 SprA-related family Oest_recep PF02159.10 CDI87351.1 - 4.8 7.3 14.6 5.8 7.0 10.1 1.1 1 0 0 1 1 1 0 Oestrogen receptor DUF3354 PF11834.3 CDI87352.1 - 0.16 11.6 0.0 0.62 9.7 0.0 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3354) DUF3824 PF12868.2 CDI87353.1 - 0.093 13.6 12.0 0.11 13.4 8.3 1.1 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) Cyclin_C PF02984.14 CDI87353.1 - 2.2 8.2 15.3 2.7 7.9 10.6 1.2 1 0 0 1 1 1 0 Cyclin, C-terminal domain RR_TM4-6 PF06459.7 CDI87354.1 - 0.029 14.2 33.4 0.046 13.6 23.1 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF913 PF06025.7 CDI87354.1 - 0.097 11.4 16.4 0.12 11.0 11.3 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DHHW PF14286.1 CDI87354.1 - 0.098 11.9 13.2 0.11 11.8 9.1 1.0 1 0 0 1 1 1 0 DHHW protein AUX_IAA PF02309.11 CDI87354.1 - 0.28 10.8 27.7 0.34 10.6 19.2 1.1 1 0 0 1 1 1 0 AUX/IAA family DUF1510 PF07423.6 CDI87354.1 - 0.35 10.1 43.7 0.44 9.8 30.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) HCO3_cotransp PF00955.16 CDI87354.1 - 0.58 8.7 5.9 0.64 8.6 4.1 1.0 1 0 0 1 1 1 0 HCO3- transporter family SAPS PF04499.10 CDI87354.1 - 1.5 7.3 22.8 1.8 7.1 15.8 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Zip PF02535.17 CDI87354.1 - 1.6 7.6 14.9 2.4 7.1 10.3 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter CDC45 PF02724.9 CDI87354.1 - 2.3 6.1 31.7 2.9 5.8 22.0 1.0 1 0 0 1 1 1 0 CDC45-like protein Paramyxo_ncap PF00973.14 CDI87354.1 - 2.5 6.6 19.9 3.3 6.3 13.8 1.2 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein MIP-T3 PF10243.4 CDI87354.1 - 2.9 6.2 68.9 3.6 5.9 47.7 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 PLRV_ORF5 PF01690.12 CDI87354.1 - 6.5 5.7 23.8 7.6 5.5 16.5 1.0 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Neur_chan_memb PF02932.11 CDI87354.1 - 6.8 6.5 22.6 7.5 6.3 15.6 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Mem_trans PF03547.13 CDI87354.1 - 7 4.8 13.1 7 4.8 9.1 1.0 1 0 0 1 1 1 0 Membrane transport protein DUF2413 PF10310.4 CDI87354.1 - 9.3 4.9 45.0 11 4.6 31.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) Parvo_coat PF00740.13 CDI87354.1 - 9.7 5.0 16.1 12 4.7 11.2 1.0 1 0 0 1 1 1 0 Parvovirus coat protein VP2 PAT1 PF09770.4 CDI87358.1 - 0.0013 17.0 68.6 0.0014 16.9 47.5 1.1 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 eIF3_subunit PF08597.5 CDI87358.1 - 0.0054 16.3 14.8 0.0054 16.3 10.2 2.7 1 1 1 2 2 2 1 Translation initiation factor eIF3 subunit Caldesmon PF02029.10 CDI87358.1 - 8.2 4.7 39.8 11 4.2 27.6 1.2 1 0 0 1 1 1 0 Caldesmon MIP-T3 PF10243.4 CDI87359.1 - 5 5.4 29.1 5.3 5.4 20.2 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DUF2413 PF10310.4 CDI87360.1 - 0.007 15.2 28.4 0.0078 15.0 19.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2413) FAM60A PF15396.1 CDI87360.1 - 0.12 12.0 23.5 0.12 12.0 16.3 1.1 1 0 0 1 1 1 0 Protein Family FAM60A Herpes_env PF01673.13 CDI87360.1 - 5.1 5.5 21.0 6.1 5.2 14.5 1.1 1 0 0 1 1 1 0 Herpesvirus putative major envelope glycoprotein Sec62 PF03839.11 CDI87360.1 - 6.1 6.1 25.8 6.8 6.0 17.9 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 Peptidase_S64 PF08192.6 CDI87360.1 - 6.3 4.9 21.2 6.8 4.8 14.7 1.1 1 0 0 1 1 1 0 Peptidase family S64 Pox_Ag35 PF03286.9 CDI87360.1 - 6.4 6.2 25.3 8.4 5.8 17.5 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein CDC45 PF02724.9 CDI87360.1 - 6.6 4.6 33.0 7.1 4.5 22.8 1.0 1 0 0 1 1 1 0 CDC45-like protein Ycf1 PF05758.7 CDI87360.1 - 8.2 4.0 34.1 8.5 3.9 23.6 1.0 1 0 0 1 1 1 0 Ycf1 DUF872 PF05915.7 CDI87360.1 - 9.7 6.0 6.5 40 4.1 4.5 1.9 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF872) Med15 PF09606.5 CDI87361.1 - 7.2e-05 21.2 70.7 7.5e-05 21.1 49.0 1.1 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal PAT1 PF09770.4 CDI87361.1 - 0.041 12.1 61.6 0.052 11.7 42.7 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 APG6 PF04111.7 CDI87361.1 - 1.9 7.4 32.1 2.5 7.0 22.3 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 HSP70 PF00012.15 CDI87361.1 - 6.2 4.5 20.2 7.4 4.3 14.0 1.1 1 0 0 1 1 1 0 Hsp70 protein Ni_hydr_CYTB PF01292.15 CDI87363.1 - 0.038 13.3 2.6 0.14 11.4 1.8 1.9 1 1 0 1 1 1 0 Prokaryotic cytochrome b561 DUF308 PF03729.8 CDI87363.1 - 0.066 13.2 5.5 9.7 6.2 0.0 3.2 3 0 0 3 3 3 0 Short repeat of unknown function (DUF308) Antirestrict PF03230.8 CDI87363.1 - 0.096 12.6 0.1 1.1 9.3 0.0 2.4 1 1 1 2 2 2 0 Antirestriction protein DUF4282 PF14110.1 CDI87363.1 - 0.66 10.2 4.2 3.2 7.9 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4282) Abhydrolase_6 PF12697.2 CDI87364.1 - 1.1e-20 74.5 0.0 3e-19 69.7 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CDI87364.1 - 4.3e-20 71.9 0.0 5.4e-20 71.6 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CDI87364.1 - 2.8e-12 46.7 0.0 1.2e-09 38.0 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 CDI87364.1 - 6.9e-10 38.5 0.0 1.1e-09 37.7 0.0 1.3 1 1 0 1 1 1 1 Prolyl oligopeptidase family DLH PF01738.13 CDI87364.1 - 3e-06 26.6 0.0 2.5e-05 23.6 0.0 1.9 1 1 0 1 1 1 1 Dienelactone hydrolase family DUF1057 PF06342.7 CDI87364.1 - 1.2e-05 24.2 0.0 1.4e-05 24.1 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1057) PGAP1 PF07819.8 CDI87364.1 - 0.00013 21.6 0.0 0.00014 21.5 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein Peptidase_S15 PF02129.13 CDI87364.1 - 0.00016 21.1 0.0 0.00074 19.0 0.0 1.7 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) DUF818 PF05677.7 CDI87364.1 - 0.0003 19.6 0.0 0.00033 19.5 0.0 1.1 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) Lipase_3 PF01764.20 CDI87364.1 - 0.00041 19.9 0.0 0.00074 19.1 0.0 1.4 1 1 0 1 1 1 1 Lipase (class 3) FSH1 PF03959.8 CDI87364.1 - 0.00088 18.7 0.0 0.0017 17.8 0.0 1.4 1 1 0 1 1 1 1 Serine hydrolase (FSH1) AXE1 PF05448.7 CDI87364.1 - 0.0012 17.4 0.1 0.0018 16.8 0.1 1.6 1 1 0 1 1 1 1 Acetyl xylan esterase (AXE1) Abhydrolase_2 PF02230.11 CDI87364.1 - 0.0025 17.2 0.0 0.011 15.2 0.0 1.8 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.8 CDI87364.1 - 0.003 17.1 0.0 0.0038 16.8 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold BAAT_C PF08840.6 CDI87364.1 - 0.0044 16.7 0.0 0.066 12.9 0.0 1.9 1 1 1 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal Thioesterase PF00975.15 CDI87364.1 - 0.005 17.0 0.0 0.0056 16.9 0.0 1.4 1 1 0 1 1 1 1 Thioesterase domain Hydrolase_4 PF12146.3 CDI87364.1 - 0.0072 16.1 0.0 0.011 15.5 0.0 1.4 1 0 0 1 1 1 1 Putative lysophospholipase PAF-AH_p_II PF03403.8 CDI87364.1 - 0.023 12.9 0.0 0.025 12.8 0.0 1.1 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II DUF2305 PF10230.4 CDI87364.1 - 0.047 13.0 0.0 0.81 9.0 0.0 2.0 1 1 0 2 2 2 0 Uncharacterised conserved protein (DUF2305) PAT1 PF09770.4 CDI87365.1 - 3.3 5.8 77.3 3.9 5.5 53.6 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 IncA PF04156.9 CDI87366.1 - 4.1e-06 26.5 22.5 4.1e-06 26.5 15.6 13.8 11 3 0 11 11 11 3 IncA protein DUF2981 PF11200.3 CDI87366.1 - 1.3 8.0 3.4 4.3 6.3 2.4 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) Herpes_DNAp_acc PF04929.7 CDI87366.1 - 9 5.1 0.0 9 5.1 0.0 11.3 8 3 4 12 12 12 0 Herpes DNA replication accessory factor IncA PF04156.9 CDI87367.1 - 0.00051 19.6 4.7 0.00051 19.6 3.3 5.8 5 1 0 5 5 5 2 IncA protein Zip PF02535.17 CDI87367.1 - 1.4 7.8 22.5 0.19 10.6 0.3 3.3 4 0 0 4 4 4 0 ZIP Zinc transporter PAT1 PF09770.4 CDI87367.1 - 1.9 6.6 131.9 0.0037 15.5 45.1 3.2 3 0 0 3 3 3 0 Topoisomerase II-associated protein PAT1 CRT10 PF08728.5 CDI87367.1 - 9.1 4.1 20.3 7.1 4.4 9.5 2.3 2 0 0 2 2 2 0 CRT10 Macoilin PF09726.4 CDI87368.1 - 1.6 6.8 37.0 1.9 6.6 25.7 1.0 1 0 0 1 1 1 0 Transmembrane protein FimP PF09766.4 CDI87370.1 - 0.0013 17.9 7.3 0.0013 17.9 5.0 3.3 3 0 0 3 3 3 3 Fms-interacting protein Baculo_PP31 PF05311.6 CDI87370.1 - 0.0041 16.4 6.0 0.0041 16.4 4.1 3.3 3 0 0 3 3 3 1 Baculovirus 33KDa late protein (PP31) Spt20 PF12090.3 CDI87370.1 - 0.086 12.1 28.2 0.29 10.4 3.6 3.4 3 0 0 3 3 3 0 Spt20 family zf-DHHC PF01529.15 CDI87370.1 - 0.34 10.2 10.8 0.59 9.4 0.2 3.2 3 0 0 3 3 3 0 DHHC palmitoyltransferase AAA_23 PF13476.1 CDI87370.1 - 2.8 8.1 30.8 0.27 11.5 1.8 3.5 4 0 0 4 4 4 0 AAA domain Activator_LAG-3 PF11498.3 CDI87370.1 - 4.7 5.8 66.2 0.59 8.8 8.9 3.4 3 0 0 3 3 3 0 Transcriptional activator LAG-3 CAF-1_p150 PF11600.3 CDI87373.1 - 0.00092 18.6 42.7 0.0046 16.3 17.4 2.2 2 0 0 2 2 2 2 Chromatin assembly factor 1 complex p150 subunit, N-terminal AAA_23 PF13476.1 CDI87373.1 - 0.16 12.2 30.6 0.58 10.4 13.6 2.3 2 0 0 2 2 2 0 AAA domain UPF0564 PF10595.4 CDI87373.1 - 0.17 10.7 43.8 0.75 8.6 6.0 2.3 2 0 0 2 2 2 0 Uncharacterised protein family UPF0564 DAP_epimerase PF01678.14 CDI87373.1 - 0.7 9.8 0.0 0.7 9.8 0.0 2.6 2 1 1 3 3 3 0 Diaminopimelate epimerase DUF3801 PF12687.2 CDI87373.1 - 1 8.8 29.1 0.098 12.2 10.9 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3801) PRP1_N PF06424.7 CDI87373.1 - 8.7 6.6 23.1 2.7 8.2 8.6 2.4 2 0 0 2 2 2 0 PRP1 splicing factor, N-terminal PCEMA1 PF07418.6 CDI87373.1 - 9.9 5.4 14.1 1.3 8.3 5.4 2.0 2 0 0 2 2 2 0 Acidic phosphoprotein precursor PCEMA1 SprA-related PF12118.3 CDI87374.1 - 0.0025 17.1 24.1 0.0025 17.1 16.7 3.9 3 1 1 4 4 4 1 SprA-related family Brix PF04427.13 CDI87374.1 - 7.6 6.1 17.5 24 4.4 12.1 1.8 1 1 0 1 1 1 0 Brix domain Arf PF00025.16 CDI87376.1 - 1.7e-26 92.5 0.0 1.6e-12 47.0 0.0 2.3 1 1 1 2 2 2 2 ADP-ribosylation factor family Claudin_2 PF13903.1 CDI87376.1 - 1.4e-05 24.8 0.8 0.052 13.2 0.0 2.9 2 1 1 3 3 3 1 PMP-22/EMP/MP20/Claudin tight junction DUF2722 PF10846.3 CDI87376.1 - 0.022 13.7 0.6 0.022 13.7 0.4 4.0 2 1 0 2 2 2 0 Protein of unknown function (DUF2722) DUF2838 PF10998.3 CDI87376.1 - 0.092 12.6 0.7 1.1 9.1 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2838) DUF3373 PF11853.3 CDI87376.1 - 0.48 8.9 5.2 1 7.8 3.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) JmjC PF02373.17 CDI87377.1 - 3.6e-34 117.4 0.8 3.6e-34 117.4 0.6 3.3 3 0 0 3 3 3 1 JmjC domain, hydroxylase zf-C5HC2 PF02928.11 CDI87377.1 - 0.00071 19.5 17.9 0.0014 18.6 12.4 1.5 1 0 0 1 1 1 1 C5HC2 zinc finger DRIM PF07539.7 CDI87378.1 - 5.4e-07 29.1 0.4 5.9e-06 25.7 0.0 3.1 2 0 0 2 2 2 1 Down-regulated in metastasis Condensation PF00668.15 CDI87379.1 - 0.00014 20.8 0.1 0.48 9.2 0.0 3.2 3 0 0 3 3 3 2 Condensation domain AATase PF07247.7 CDI87379.1 - 0.042 12.4 0.0 0.49 8.8 0.0 2.5 3 0 0 3 3 3 0 Alcohol acetyltransferase OTCace_N PF02729.16 CDI87381.1 - 7.8e-27 93.6 0.1 7.8e-27 93.6 0.1 1.7 2 0 0 2 2 2 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain RNB PF00773.14 CDI87381.1 - 0.0027 17.0 0.1 0.0031 16.8 0.1 1.1 1 0 0 1 1 1 1 RNB domain SGT1 PF07093.6 CDI87381.1 - 0.0038 15.6 0.4 0.0046 15.3 0.3 1.1 1 0 0 1 1 1 1 SGT1 protein PAXIP1_C PF15364.1 CDI87381.1 - 0.0073 16.2 2.5 0.015 15.1 1.7 1.4 1 0 0 1 1 1 1 PAXIP1-associated-protein-1 C term PTIP binding protein TraT PF05818.7 CDI87381.1 - 0.1 11.9 3.5 4.1 6.7 0.4 2.4 2 1 0 2 2 2 0 Enterobacterial TraT complement resistance protein Pex14_N PF04695.8 CDI87381.1 - 0.41 10.6 15.5 0.11 12.4 1.3 2.3 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Suf PF05843.9 CDI87381.1 - 0.69 9.5 6.2 0.15 11.7 1.8 1.7 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) Folliculin PF11704.3 CDI87381.1 - 0.84 9.2 6.0 0.1 12.1 0.8 1.7 2 0 0 2 2 2 0 Vesicle coat protein involved in Golgi to plasma membrane transport DUF2802 PF10975.3 CDI87381.1 - 1.4 8.7 12.0 2.5 7.9 8.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2802) DUF1117 PF06547.7 CDI87381.1 - 1.6 8.8 8.6 3.2 7.8 6.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1117) RAP1 PF07218.6 CDI87381.1 - 8.2 4.3 14.0 11 4.0 9.7 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) RskA PF10099.4 CDI87385.1 - 0.00014 21.6 40.4 0.00059 19.6 1.3 3.3 3 0 0 3 3 3 2 Anti-sigma-K factor rskA Med15 PF09606.5 CDI87385.1 - 0.015 13.5 72.9 0.019 13.1 50.6 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal PRP1_N PF06424.7 CDI87385.1 - 0.042 14.1 0.3 0.042 14.1 0.2 3.2 3 0 0 3 3 3 0 PRP1 splicing factor, N-terminal AF1Q PF15017.1 CDI87385.1 - 2.2 8.2 21.1 0.076 12.9 0.6 3.3 3 0 0 3 3 3 0 Drug resistance and apoptosis regulator BLVR PF06375.6 CDI87385.1 - 5.7 6.7 28.3 1 9.1 0.9 3.1 3 0 0 3 3 3 0 Bovine leukaemia virus receptor (BLVR) Baculo_PP31 PF05311.6 CDI87385.1 - 7.7 5.7 28.5 0.7 9.1 0.2 3.0 3 0 0 3 3 3 0 Baculovirus 33KDa late protein (PP31) HemX PF04375.9 CDI87386.1 - 0.0016 17.1 18.4 0.0025 16.5 12.7 1.2 1 0 0 1 1 1 1 HemX Macoilin PF09726.4 CDI87386.1 - 0.023 12.9 30.1 0.031 12.5 20.9 1.0 1 0 0 1 1 1 0 Transmembrane protein PAP1 PF08601.5 CDI87386.1 - 0.06 13.0 31.6 0.078 12.6 21.9 1.0 1 0 0 1 1 1 0 Transcription factor PAP1 DUF605 PF04652.11 CDI87386.1 - 0.58 9.4 30.4 0.81 9.0 21.1 1.1 1 0 0 1 1 1 0 Vta1 like FimP PF09766.4 CDI87386.1 - 1.3 8.0 10.1 0.29 10.1 1.9 2.1 2 0 0 2 2 2 0 Fms-interacting protein TFIIA PF03153.8 CDI87386.1 - 3.1 7.5 25.5 4.9 6.9 17.7 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF1777 PF08648.7 CDI87386.1 - 3.3 7.4 22.9 0.13 11.9 11.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1777) GMC_oxred_C PF05199.8 CDI87387.1 - 0.0014 18.9 0.3 0.0014 18.9 0.2 2.9 3 2 0 3 3 3 1 GMC oxidoreductase Prok-RING_1 PF14446.1 CDI87387.1 - 0.0072 16.0 6.5 0.0072 16.0 4.5 1.8 2 0 0 2 2 2 1 Prokaryotic RING finger family 1 MACPF PF01823.14 CDI87387.1 - 3 7.4 16.0 1.3 8.7 0.8 2.2 2 0 0 2 2 2 0 MAC/Perforin domain HypA PF01155.14 CDI87387.1 - 3.1 7.5 5.7 4.9 6.8 2.3 2.2 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family ELL PF10390.4 CDI87387.1 - 6 6.0 10.1 3.4 6.8 3.0 2.2 2 0 0 2 2 2 0 RNA polymerase II elongation factor ELL Pex14_N PF04695.8 CDI87388.1 - 0.0045 17.0 14.4 0.0045 17.0 10.0 7.2 5 2 1 6 6 6 2 Peroxisomal membrane anchor protein (Pex14p) conserved region BAF1_ABF1 PF04684.8 CDI87389.1 - 1.4e-06 27.4 14.9 1.4e-06 27.4 10.3 7.5 4 3 2 7 7 7 1 BAF1 / ABF1 chromatin reorganising factor Zip PF02535.17 CDI87389.1 - 1.8 7.4 5.3 0.25 10.2 0.2 1.9 2 0 0 2 2 2 0 ZIP Zinc transporter 5-FTHF_cyc-lig PF01812.15 CDI87390.1 - 6e-16 58.7 0.0 5e-11 42.7 0.0 2.4 2 0 0 2 2 2 2 5-formyltetrahydrofolate cyclo-ligase family E_Pc_C PF06752.7 CDI87390.1 - 0.0029 17.1 17.4 0.0029 17.1 12.1 2.2 2 0 0 2 2 2 1 Enhancer of Polycomb C-terminus Auxin_repressed PF05564.7 CDI87390.1 - 0.15 12.6 0.2 0.15 12.6 0.2 2.0 2 0 0 2 2 2 0 Dormancy/auxin associated protein zf-DHHC PF01529.15 CDI87390.1 - 0.15 11.4 4.2 0.24 10.7 2.0 1.8 2 0 0 2 2 2 0 DHHC palmitoyltransferase OATP PF03137.15 CDI87390.1 - 2.4 6.0 3.9 4.2 5.2 2.7 1.4 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family DivIC PF04977.10 CDI87390.1 - 7.6 6.1 21.4 1.5 8.3 6.0 2.3 2 0 0 2 2 2 0 Septum formation initiator DUF773 PF05600.7 CDI87391.1 - 4e-23 81.9 22.6 1.5e-11 43.8 15.5 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF773) DUF572 PF04502.8 CDI87391.1 - 0.007 15.6 34.0 0.096 11.8 16.7 2.3 2 0 0 2 2 2 2 Family of unknown function (DUF572) RAP1 PF07218.6 CDI87391.1 - 0.03 12.4 26.3 0.034 12.2 9.0 2.1 2 0 0 2 2 2 0 Rhoptry-associated protein 1 (RAP-1) DUF2217 PF10265.4 CDI87391.1 - 0.28 9.9 37.5 0.018 13.8 5.6 2.4 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2217) TPPK_C PF12555.3 CDI87391.1 - 0.39 10.4 5.9 0.4 10.4 3.0 1.8 2 0 0 2 2 2 0 Thiamine pyrophosphokinase C terminal tRNA-Thr_ED PF08915.6 CDI87391.1 - 3.5 7.6 6.9 0.97 9.4 1.1 2.5 2 0 0 2 2 2 0 Archaea-specific editing domain of threonyl-tRNA synthetase Pol_alpha_B_N PF08418.5 CDI87391.1 - 3.7 7.0 38.8 2.2 7.7 3.7 3.0 2 1 0 2 2 2 0 DNA polymerase alpha subunit B N-terminal GP40 PF11025.3 CDI87391.1 - 5.6 6.5 23.9 0.5 9.9 5.0 2.6 2 0 0 2 2 2 0 Glycoprotein GP40 of Cryptosporidium Activator_LAG-3 PF11498.3 CDI87392.1 - 0.0087 14.8 22.0 0.0093 14.7 15.2 1.1 1 0 0 1 1 1 1 Transcriptional activator LAG-3 TraT PF05818.7 CDI87392.1 - 0.019 14.4 14.5 0.022 14.1 10.0 1.1 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein DUF2232 PF09991.4 CDI87392.1 - 0.038 12.9 5.4 0.045 12.7 3.7 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) MSP1_C PF07462.6 CDI87392.1 - 0.096 11.0 17.8 0.11 10.8 12.3 1.2 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Med15 PF09606.5 CDI87392.1 - 0.35 9.0 33.6 0.4 8.8 23.3 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Suf PF05843.9 CDI87392.1 - 2.9 7.5 10.5 3 7.5 7.3 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Bac_Ubq_Cox PF01654.12 CDI87392.1 - 3 6.1 10.7 3.2 6.0 7.4 1.0 1 0 0 1 1 1 0 Bacterial Cytochrome Ubiquinol Oxidase RAB3GAP2_N PF14655.1 CDI87392.1 - 3.9 6.3 12.3 4.6 6.1 8.5 1.1 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Serinc PF03348.10 CDI87392.1 - 4.3 5.9 10.6 4.7 5.8 7.3 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) DUF3450 PF11932.3 CDI87392.1 - 8.1 5.6 31.0 12 5.1 21.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) BTB_2 PF02214.17 CDI87393.1 - 0.00028 21.0 5.2 0.00084 19.4 0.5 2.7 2 1 0 2 2 1 1 BTB/POZ domain Neur_chan_memb PF02932.11 CDI87393.1 - 0.0014 18.6 4.3 0.0014 18.6 3.0 1.4 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region AAA_11 PF13086.1 CDI87393.1 - 0.011 15.3 14.5 0.08 12.5 5.4 2.2 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.18 CDI87393.1 - 0.016 15.0 4.1 0.016 15.0 2.8 2.2 2 0 0 2 2 2 0 Dynamin family Serinc PF03348.10 CDI87393.1 - 0.046 12.4 16.4 0.66 8.6 0.2 2.1 2 0 0 2 2 2 0 Serine incorporator (Serinc) zf-DHHC PF01529.15 CDI87393.1 - 0.057 12.8 10.8 0.61 9.4 0.1 2.3 2 0 0 2 2 2 0 DHHC palmitoyltransferase CBF PF03914.12 CDI87393.1 - 0.089 12.2 6.3 1.2 8.5 0.9 2.2 2 0 0 2 2 2 0 CBF/Mak21 family DUF1266 PF06889.6 CDI87393.1 - 0.1 12.3 12.7 0.39 10.4 3.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1266) DUF4011 PF13195.1 CDI87393.1 - 0.13 12.3 10.5 1.9 8.4 3.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4011) Pex16 PF08610.5 CDI87393.1 - 0.13 11.2 18.4 0.06 12.3 4.5 2.2 2 0 0 2 2 2 0 Peroxisomal membrane protein (Pex16) HGTP_anticodon2 PF12745.2 CDI87393.1 - 0.16 11.0 14.9 0.014 14.5 2.2 2.1 2 0 0 2 2 2 0 Anticodon binding domain of tRNAs FYDLN_acid PF09538.5 CDI87393.1 - 0.17 12.4 7.3 0.72 10.4 1.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) GOLD_2 PF13897.1 CDI87393.1 - 0.19 11.9 8.4 0.069 13.3 1.0 2.2 2 0 0 2 2 2 0 Golgi-dynamics membrane-trafficking BORG_CEP PF14957.1 CDI87393.1 - 0.26 12.1 11.7 1.6 9.6 3.2 2.3 2 0 0 2 2 2 0 Cdc42 effector Peptidase_S49_N PF08496.5 CDI87393.1 - 0.32 10.7 24.0 0.41 10.4 8.4 2.4 2 1 0 2 2 2 0 Peptidase family S49 N-terminal DUF1943 PF09172.6 CDI87393.1 - 0.38 9.5 10.0 1.8 7.3 2.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1943) CPSF100_C PF13299.1 CDI87393.1 - 0.47 10.6 17.0 4.6 7.4 0.2 2.2 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal DUF912 PF06024.7 CDI87393.1 - 0.62 10.1 17.7 0.42 10.7 4.6 2.5 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF2126 PF09899.4 CDI87393.1 - 0.68 7.9 15.4 0.37 8.7 5.1 2.1 2 0 0 2 2 2 0 Putative amidoligase enzyme (DUF2126) PH_4 PF15404.1 CDI87393.1 - 0.8 9.2 18.6 0.4 10.2 4.9 2.3 2 0 0 2 2 2 0 Pleckstrin homology domain MRP-S31 PF15433.1 CDI87393.1 - 1.1 8.5 25.8 0.12 11.8 7.9 2.3 2 0 0 2 2 2 0 Mitochondrial 28S ribosomal protein S31 Herpes_UL87 PF03043.9 CDI87393.1 - 1.2 7.4 10.6 1.7 6.9 7.3 1.2 1 0 0 1 1 1 0 Herpesvirus UL87 family APC8 PF04049.8 CDI87393.1 - 1.4 8.6 13.9 5 6.8 4.3 2.3 2 0 0 2 2 2 0 Anaphase promoting complex subunit 8 / Cdc23 HCV_NS5a_C PF12941.2 CDI87393.1 - 1.4 8.4 7.0 0.91 9.0 1.8 2.2 2 0 0 2 2 2 0 HCV NS5a protein C-terminal region AUX_IAA PF02309.11 CDI87393.1 - 1.7 8.3 20.9 0.44 10.2 7.2 2.1 2 0 0 2 2 2 0 AUX/IAA family DUF607 PF04678.8 CDI87393.1 - 2.4 8.0 19.0 1.1 9.0 1.3 2.2 2 0 0 2 2 2 0 Protein of unknown function, DUF607 Glyco_transf_15 PF01793.11 CDI87393.1 - 2.5 6.9 17.8 0.17 10.7 3.7 2.1 2 0 0 2 2 2 0 Glycolipid 2-alpha-mannosyltransferase GAGA_bind PF06217.7 CDI87393.1 - 2.6 7.9 22.4 0.24 11.3 7.7 2.1 2 0 0 2 2 2 0 GAGA binding protein-like family DUF4628 PF15429.1 CDI87393.1 - 2.7 7.3 14.5 0.82 9.0 2.9 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4628) DUF342 PF03961.8 CDI87393.1 - 3.4 5.9 16.2 2.5 6.4 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF342) DUF3449 PF11931.3 CDI87393.1 - 3.9 6.9 20.9 1.3 8.5 6.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3449) DUF4045 PF13254.1 CDI87393.1 - 4.6 6.4 16.7 0.17 11.1 3.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4045) Plasmodium_Vir PF05795.6 CDI87393.1 - 4.8 6.2 7.3 0.79 8.8 0.7 2.0 2 0 0 2 2 2 0 Plasmodium vivax Vir protein XAP5 PF04921.9 CDI87393.1 - 5.1 6.6 13.3 0.47 9.9 2.2 2.2 2 0 0 2 2 2 0 XAP5, circadian clock regulator Folate_carrier PF01770.13 CDI87393.1 - 5.3 5.4 13.3 1.1 7.6 3.3 2.1 2 0 0 2 2 2 0 Reduced folate carrier FAM60A PF15396.1 CDI87393.1 - 5.4 6.7 15.9 1.3 8.7 4.3 2.2 2 0 0 2 2 2 0 Protein Family FAM60A Hid1 PF12722.2 CDI87393.1 - 5.6 4.5 20.8 2.2 5.8 0.3 2.1 2 0 0 2 2 2 0 High-temperature-induced dauer-formation protein Cyto_heme_lyase PF01265.12 CDI87393.1 - 5.9 6.3 24.1 0.37 10.3 8.2 2.1 2 0 0 2 2 2 0 Cytochrome c/c1 heme lyase DUF4484 PF14831.1 CDI87393.1 - 6 6.9 13.3 0.62 10.1 2.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4484) Eapp_C PF10238.4 CDI87393.1 - 6.6 6.6 17.0 2.1 8.2 4.4 2.4 2 0 0 2 2 2 0 E2F-associated phosphoprotein Peroxin-13_N PF04088.8 CDI87393.1 - 6.6 6.6 14.7 2.9 7.8 4.0 2.3 2 0 0 2 2 2 0 Peroxin 13, N-terminal region Band_3_cyto PF07565.8 CDI87393.1 - 7.2 6.0 26.8 0.75 9.2 8.6 2.1 2 0 0 2 2 2 0 Band 3 cytoplasmic domain BNR_3 PF13859.1 CDI87393.1 - 8.9 5.2 12.3 3.8 6.5 4.3 2.2 2 1 0 2 2 2 0 BNR repeat-like domain Presenilin PF01080.12 CDI87393.1 - 9.3 4.9 9.6 18 3.9 4.0 2.1 2 0 0 2 2 2 0 Presenilin DUF2072 PF09845.4 CDI87393.1 - 9.5 6.1 12.8 0.85 9.5 2.8 2.4 2 0 0 2 2 2 0 Zn-ribbon containing protein (DUF2072) OmpH PF03938.9 CDI87394.1 - 0.00073 19.5 39.5 0.00073 19.5 27.4 11.2 3 3 3 7 7 7 1 Outer membrane protein (OmpH-like) Exo_endo_phos PF03372.18 CDI87395.1 - 6.9e-13 49.1 2.2 4.5e-10 39.8 0.3 2.1 1 1 0 2 2 2 2 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 CDI87395.1 - 4.9e-09 35.8 0.0 7e-05 22.4 0.0 2.3 2 0 0 2 2 2 2 Endonuclease-reverse transcriptase PAZ_siRNAbind PF12212.3 CDI87395.1 - 0.058 13.0 0.1 14 5.4 0.0 2.3 2 0 0 2 2 2 0 Piwi/Argonaute/Zwille siRNA-binding domain TFIIS_C PF01096.13 CDI87396.1 - 6.7e-14 51.2 11.7 7.3e-14 51.1 3.6 3.1 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) Terminase_GpA PF05876.7 CDI87396.1 - 0.031 12.6 2.8 0.88 7.8 0.0 2.1 2 0 0 2 2 2 0 Phage terminase large subunit (GpA) Lar_restr_allev PF14354.1 CDI87396.1 - 0.082 13.2 7.9 4 7.8 1.9 3.2 3 0 0 3 3 3 0 Restriction alleviation protein Lar Zn-ribbon_8 PF09723.5 CDI87396.1 - 0.091 12.7 8.3 10 6.1 0.0 4.5 4 0 0 4 4 4 0 Zinc ribbon domain Zn_Tnp_IS1595 PF12760.2 CDI87396.1 - 0.16 11.7 9.2 0.64 9.8 2.8 3.0 3 0 0 3 3 3 0 Transposase zinc-ribbon domain DNA_RNApol_7kD PF03604.8 CDI87396.1 - 0.4 10.1 0.1 0.4 10.1 0.1 4.3 4 0 0 4 4 4 0 DNA directed RNA polymerase, 7 kDa subunit zinc_ribbon_4 PF13717.1 CDI87396.1 - 1.4 8.6 0.0 1.4 8.6 0.0 4.0 4 0 0 4 4 4 0 zinc-ribbon domain zf-ribbon_3 PF13248.1 CDI87396.1 - 1.7 7.9 8.0 7.9 5.8 0.1 3.8 4 0 0 4 4 4 0 zinc-ribbon domain zinc_ribbon_5 PF13719.1 CDI87396.1 - 5.4 6.6 11.8 2 8.0 0.0 3.9 4 0 0 4 4 4 0 zinc-ribbon domain Ribosomal_L37e PF01907.14 CDI87396.1 - 8.5 6.2 9.2 5.6 6.8 0.1 3.0 3 0 0 3 3 3 0 Ribosomal protein L37e DUF1510 PF07423.6 CDI87397.1 - 0.008 15.5 16.6 0.0085 15.4 11.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) MRI PF15325.1 CDI87397.1 - 0.032 15.1 5.8 0.043 14.7 4.0 1.1 1 0 0 1 1 1 0 Modulator of retrovirus infection FAM176 PF14851.1 CDI87397.1 - 0.076 12.6 7.0 0.1 12.2 4.9 1.3 1 0 0 1 1 1 0 FAM176 family YqfQ PF14181.1 CDI87397.1 - 0.2 11.7 19.7 0.24 11.4 13.6 1.1 1 0 0 1 1 1 0 YqfQ-like protein RIC3 PF15361.1 CDI87397.1 - 0.24 11.6 17.3 0.28 11.4 12.0 1.1 1 0 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 Pap_E4 PF02711.9 CDI87397.1 - 0.27 12.0 18.2 0.34 11.7 12.6 1.1 1 0 0 1 1 1 0 E4 protein Zip PF02535.17 CDI87397.1 - 0.37 9.7 9.2 0.38 9.7 6.4 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter SelP_N PF04592.9 CDI87397.1 - 0.5 9.7 17.6 0.49 9.7 12.2 1.0 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Kei1 PF08552.6 CDI87397.1 - 0.57 9.8 13.5 0.65 9.6 9.4 1.0 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 DDHD PF02862.12 CDI87397.1 - 1.1 8.9 16.3 1.3 8.8 11.3 1.0 1 0 0 1 1 1 0 DDHD domain Rtf2 PF04641.7 CDI87397.1 - 1.2 8.2 18.0 1.3 8.1 12.4 1.0 1 0 0 1 1 1 0 Rtf2 RING-finger Gti1_Pac2 PF09729.4 CDI87397.1 - 1.4 8.7 13.4 1.7 8.4 9.3 1.1 1 0 0 1 1 1 0 Gti1/Pac2 family NARP1 PF12569.3 CDI87397.1 - 1.5 7.5 19.3 1.6 7.3 13.4 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 FLO_LFY PF01698.11 CDI87397.1 - 1.5 7.6 17.6 1.7 7.4 12.2 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein Tim54 PF11711.3 CDI87397.1 - 1.5 7.3 13.4 1.6 7.2 9.3 1.0 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 RNA_pol_Rpc4 PF05132.9 CDI87397.1 - 1.6 8.7 16.5 1.9 8.4 11.4 1.1 1 0 0 1 1 1 0 RNA polymerase III RPC4 Nha1_C PF08619.5 CDI87397.1 - 1.6 7.8 19.1 1.8 7.7 13.2 1.0 1 0 0 1 1 1 0 Alkali metal cation/H+ antiporter Nha1 C terminus F-protein PF00469.15 CDI87397.1 - 1.8 7.8 16.2 1.9 7.8 11.2 1.0 1 0 0 1 1 1 0 Negative factor, (F-Protein) or Nef Peptidase_U57 PF05582.7 CDI87397.1 - 1.8 7.4 14.0 1.9 7.3 9.7 1.0 1 0 0 1 1 1 0 YabG peptidase U57 DUF2058 PF09831.4 CDI87397.1 - 1.9 8.3 32.0 2.2 8.1 22.2 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2058) AIF_C PF14721.1 CDI87397.1 - 1.9 8.7 15.7 2.3 8.4 10.9 1.1 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Pox_Ag35 PF03286.9 CDI87397.1 - 1.9 7.9 13.5 2.2 7.7 9.4 1.0 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DUF1764 PF08576.5 CDI87397.1 - 2 9.2 21.0 2.6 8.8 14.6 1.2 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) Neur_chan_memb PF02932.11 CDI87397.1 - 2 8.2 12.9 2.2 8.1 8.9 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF3449 PF11931.3 CDI87397.1 - 2.1 7.8 19.4 2.4 7.6 13.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3449) RR_TM4-6 PF06459.7 CDI87397.1 - 2.1 8.1 19.7 2.4 8.0 13.7 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF2514 PF10721.4 CDI87397.1 - 2.3 7.8 23.0 2.3 7.8 16.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) Hom_end_hint PF05203.11 CDI87397.1 - 2.4 7.8 14.6 2.7 7.6 10.1 1.0 1 0 0 1 1 1 0 Hom_end-associated Hint SAPS PF04499.10 CDI87397.1 - 2.4 6.6 15.9 2.7 6.5 11.0 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Folate_carrier PF01770.13 CDI87397.1 - 2.5 6.4 12.2 2.8 6.3 8.5 1.0 1 0 0 1 1 1 0 Reduced folate carrier NPR3 PF03666.8 CDI87397.1 - 2.6 6.4 18.4 2.9 6.3 12.7 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 BORG_CEP PF14957.1 CDI87397.1 - 2.7 8.9 13.2 3.2 8.7 9.2 1.1 1 0 0 1 1 1 0 Cdc42 effector FAM60A PF15396.1 CDI87397.1 - 2.8 7.6 14.3 3.2 7.4 9.9 1.1 1 0 0 1 1 1 0 Protein Family FAM60A FAM91_C PF14648.1 CDI87397.1 - 3 6.5 10.3 3.4 6.4 7.2 1.0 1 0 0 1 1 1 0 FAM91 C-terminus GAGA_bind PF06217.7 CDI87397.1 - 3.2 7.6 17.8 3.5 7.4 12.3 1.0 1 0 0 1 1 1 0 GAGA binding protein-like family ALG3 PF05208.8 CDI87397.1 - 3.6 6.7 8.9 3.8 6.6 6.1 1.1 1 0 0 1 1 1 0 ALG3 protein DUF4045 PF13254.1 CDI87397.1 - 3.6 6.7 17.4 4 6.6 12.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) FNIP_N PF14636.1 CDI87397.1 - 3.6 8.0 18.6 4.1 7.8 12.9 1.1 1 0 0 1 1 1 0 Folliculin-interacting protein N-terminus RP-C_C PF11800.3 CDI87397.1 - 3.7 7.2 18.0 3.9 7.1 12.5 1.0 1 0 0 1 1 1 0 Replication protein C C-terminal region DUF966 PF06136.8 CDI87397.1 - 3.7 6.8 16.1 4.1 6.7 11.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF966) CDC45 PF02724.9 CDI87397.1 - 3.7 5.4 17.1 4.3 5.2 11.9 1.0 1 0 0 1 1 1 0 CDC45-like protein Dynamin_N PF00350.18 CDI87397.1 - 3.9 7.2 10.8 5.4 6.8 7.5 1.3 1 0 0 1 1 1 0 Dynamin family Band_3_cyto PF07565.8 CDI87397.1 - 3.9 6.8 20.7 4.6 6.6 14.4 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Stig1 PF04885.8 CDI87397.1 - 4 7.6 7.7 5.3 7.2 5.3 1.2 1 0 0 1 1 1 0 Stigma-specific protein, Stig1 Herpes_DNAp_acc PF04929.7 CDI87397.1 - 4.2 6.2 14.7 4.6 6.1 10.2 1.0 1 0 0 1 1 1 0 Herpes DNA replication accessory factor DUF2052 PF09747.4 CDI87397.1 - 4.3 7.2 23.3 5 7.0 16.1 1.1 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) Spore_coat_CotO PF14153.1 CDI87397.1 - 4.4 6.7 29.3 5.1 6.4 20.3 1.0 1 0 0 1 1 1 0 Spore coat protein CotO AUX_IAA PF02309.11 CDI87397.1 - 4.5 6.9 15.6 5.1 6.7 10.8 1.1 1 0 0 1 1 1 0 AUX/IAA family DUF2201_N PF13203.1 CDI87397.1 - 4.6 6.3 20.9 5.4 6.1 14.5 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain Senescence_reg PF04520.8 CDI87397.1 - 5.1 7.5 12.3 5.5 7.4 8.5 1.1 1 0 0 1 1 1 0 Senescence regulator Afi1 PF07792.7 CDI87397.1 - 5.2 7.0 17.0 6.8 6.7 11.8 1.2 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking UPF0560 PF10577.4 CDI87397.1 - 5.2 5.1 30.9 5.6 5.0 21.4 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Hid1 PF12722.2 CDI87397.1 - 5.2 4.6 20.4 5.7 4.4 14.1 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Raftlin PF15250.1 CDI87397.1 - 5.3 5.4 18.4 5.8 5.3 12.7 1.0 1 0 0 1 1 1 0 Raftlin EPL1 PF10513.4 CDI87397.1 - 5.4 7.2 21.5 6.3 7.0 14.9 1.1 1 0 0 1 1 1 0 Enhancer of polycomb-like SID-1_RNA_chan PF13965.1 CDI87397.1 - 5.5 5.0 11.0 5.1 5.1 7.7 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DUF4175 PF13779.1 CDI87397.1 - 6 4.4 53.3 7 4.2 37.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) DUF4512 PF14975.1 CDI87397.1 - 6.1 7.7 14.4 7.6 7.4 10.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4512) Pex14_N PF04695.8 CDI87397.1 - 6.2 6.8 27.8 9.5 6.2 19.3 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Asp-B-Hydro_N PF05279.6 CDI87397.1 - 6.3 6.5 14.7 7.1 6.4 10.2 1.0 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Glyco_transf_6 PF03414.8 CDI87397.1 - 6.4 5.1 14.4 7.1 4.9 10.0 1.0 1 0 0 1 1 1 0 Glycosyltransferase family 6 DUF3260 PF11658.3 CDI87397.1 - 6.6 4.7 18.7 7.6 4.5 12.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3260) Glyco_transf_15 PF01793.11 CDI87397.1 - 6.6 5.5 19.5 7.5 5.3 13.5 1.1 1 0 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase RNA_pol_Rpb1_5 PF04998.12 CDI87397.1 - 6.8 5.8 12.1 7.6 5.7 8.4 1.0 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 CPSF100_C PF13299.1 CDI87397.1 - 6.8 6.8 17.3 7.7 6.6 12.0 1.1 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Lin-8 PF03353.10 CDI87397.1 - 6.9 5.8 22.3 7.6 5.7 15.5 1.0 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist SpoVR PF04293.8 CDI87397.1 - 7.4 4.8 19.0 8.4 4.6 13.1 1.0 1 0 0 1 1 1 0 SpoVR like protein DUF913 PF06025.7 CDI87397.1 - 7.5 5.1 11.7 7.9 5.1 8.1 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DUF2126 PF09899.4 CDI87397.1 - 8.4 4.2 17.3 9.6 4.0 12.0 1.0 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) Baculo_PP31 PF05311.6 CDI87397.1 - 8.9 5.4 19.8 10 5.2 13.7 1.1 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) Serinc PF03348.10 CDI87397.1 - 9.1 4.8 17.5 11 4.6 12.1 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) DUF2370 PF10176.4 CDI87397.1 - 9.2 5.5 12.8 10 5.4 8.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) Endonuc_Holl PF10107.4 CDI87397.1 - 9.4 5.9 19.5 11 5.7 13.5 1.1 1 0 0 1 1 1 0 Endonuclease related to archaeal Holliday junction resolvase DUF3464 PF11947.3 CDI87397.1 - 9.5 5.6 19.4 13 5.2 13.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) OATP PF03137.15 CDI87397.1 - 9.6 4.1 14.1 11 3.9 9.8 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Gly_rich PF12810.2 CDI87398.1 - 0.00077 19.1 4.7 0.00077 19.1 3.3 8.6 7 2 1 9 9 9 2 Glycine rich protein APC_CDC26 PF10471.4 CDI87399.1 - 0.0089 16.7 21.1 0.15 12.8 4.1 2.2 2 0 0 2 2 2 2 Anaphase-promoting complex APC subunit 1 LNP1 PF15419.1 CDI87399.1 - 0.11 12.5 4.0 0.13 12.3 2.7 1.1 1 0 0 1 1 1 0 Leukemia NUP98 fusion partner 1 Peptidase_M64 PF09471.5 CDI87399.1 - 0.16 11.5 4.4 0.17 11.4 3.0 1.3 1 0 0 1 1 1 0 IgA Peptidase M64 PAT1 PF09770.4 CDI87399.1 - 0.35 9.0 29.7 0.41 8.8 20.6 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Imm15 PF15590.1 CDI87399.1 - 0.5 9.4 3.2 0.18 10.8 0.1 1.8 2 0 0 2 2 2 0 Immunity protein 15 Presenilin PF01080.12 CDI87399.1 - 0.69 8.6 7.5 0.77 8.5 5.2 1.0 1 0 0 1 1 1 0 Presenilin Rho_Binding PF08912.6 CDI87399.1 - 1.1 9.5 9.4 0.33 11.2 1.4 2.2 2 0 0 2 2 2 0 Rho Binding DUF4316 PF14195.1 CDI87399.1 - 1.8 8.7 8.0 1.1 9.3 1.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4316) Macoilin PF09726.4 CDI87399.1 - 2.3 6.4 7.0 3.2 5.9 4.8 1.2 1 0 0 1 1 1 0 Transmembrane protein PHD_3 PF13922.1 CDI87399.1 - 2.4 8.4 17.2 3.5 7.9 2.4 2.3 2 0 0 2 2 2 0 PHD domain of transcriptional enhancer, Asx TFIIA PF03153.8 CDI87399.1 - 2.4 7.9 20.2 2.8 7.7 14.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit UCH PF00443.24 CDI87399.1 - 3.6 6.6 7.6 3.8 6.5 5.3 1.1 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase DUF4175 PF13779.1 CDI87399.1 - 3.6 5.1 21.7 4.5 4.8 15.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) dsDNA_bind PF01984.15 CDI87399.1 - 4.5 7.3 21.7 5.1 7.1 6.3 2.2 2 0 0 2 2 2 0 Double-stranded DNA-binding domain Metal_resist PF13801.1 CDI87399.1 - 4.8 7.1 14.6 7.7 6.5 4.1 2.1 2 0 0 2 2 2 0 Heavy-metal resistance ABC_tran_2 PF12848.2 CDI87399.1 - 5 7.0 14.0 7.2 6.5 0.2 2.2 2 0 0 2 2 2 0 ABC transporter Med15 PF09606.5 CDI87399.1 - 5.1 5.1 32.9 5.5 5.0 22.8 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal HAUS6_N PF14661.1 CDI87399.1 - 5.6 6.2 12.5 7.3 5.8 8.7 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Hid1 PF12722.2 CDI87399.1 - 6.1 4.3 10.0 7.3 4.1 6.9 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF2489 PF10675.4 CDI87399.1 - 6.3 6.4 18.6 0.62 9.7 4.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2489) DUF2802 PF10975.3 CDI87399.1 - 9.9 6.0 20.3 3.1 7.6 1.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2802) Dicty_REP PF05086.7 CDI87399.1 - 10 3.7 9.4 11 3.6 6.5 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Kinesin PF00225.18 CDI87401.1 - 3e-100 335.2 0.0 5.9e-100 334.2 0.0 1.5 1 0 0 1 1 1 1 Kinesin motor domain KIF1B PF12423.3 CDI87401.1 - 0.0005 20.0 0.0 0.0023 17.9 0.0 2.3 1 0 0 1 1 1 1 Kinesin protein 1B FHA PF00498.21 CDI87401.1 - 0.056 13.5 0.0 0.23 11.5 0.0 2.1 2 0 0 2 2 2 0 FHA domain PKD_channel PF08016.7 CDI87402.1 - 0.00039 18.9 10.2 0.00039 18.9 7.0 4.5 4 1 1 5 5 5 3 Polycystin cation channel AMP-binding PF00501.23 CDI87403.1 - 1.7e-10 39.8 0.1 4.4e-08 31.9 0.0 2.1 2 0 0 2 2 2 2 AMP-binding enzyme Peripla_BP_6 PF13458.1 CDI87403.1 - 0.088 12.1 0.0 2 7.6 0.0 2.1 2 0 0 2 2 2 0 Periplasmic binding protein zf-C2H2_2 PF12756.2 CDI87404.1 - 5.2e-13 48.9 9.6 4.7e-11 42.6 1.3 3.9 4 0 0 4 4 4 2 C2H2 type zinc-finger (2 copies) DUF3449 PF11931.3 CDI87404.1 - 0.17 11.4 0.0 0.17 11.4 0.0 2.6 3 1 1 4 4 4 0 Domain of unknown function (DUF3449) zf-met PF12874.2 CDI87404.1 - 1.4 9.2 5.1 3.7 7.9 0.4 2.7 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Mito_carr PF00153.22 CDI87405.1 - 5.3e-62 205.5 4.2 3.1e-25 87.7 0.0 4.4 4 0 0 4 4 4 4 Mitochondrial carrier protein DOR PF14839.1 CDI87406.1 - 2.3 7.9 11.9 2.6 7.7 8.2 1.0 1 0 0 1 1 1 0 DOR family Corona_nucleoca PF00937.13 CDI87406.1 - 9.1 5.1 14.3 11 4.8 9.9 1.0 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein WLM PF08325.5 CDI87408.1 - 1.5e-07 31.4 0.0 1.5e-07 31.4 0.0 3.9 4 1 0 4 4 4 1 WLM domain DUF45 PF01863.12 CDI87408.1 - 0.00018 21.3 0.0 0.00018 21.3 0.0 3.2 5 0 0 5 5 5 1 Protein of unknown function DUF45 Ycf1 PF05758.7 CDI87410.1 - 0.1 10.3 0.0 0.12 10.0 0.0 1.1 1 0 0 1 1 1 0 Ycf1 PAM2 PF07145.10 CDI87411.1 - 0.0014 17.9 1.2 0.0035 16.7 0.8 1.7 1 0 0 1 1 1 1 Ataxin-2 C-terminal region DNA_pol_B PF00136.16 CDI87412.1 - 1e-70 238.8 0.0 2e-70 237.8 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase family B zf-C4pol PF14260.1 CDI87412.1 - 2.7e-11 43.2 4.1 2.7e-11 43.2 2.8 4.4 5 0 0 5 5 5 1 C4-type zinc-finger of DNA polymerase delta DNA_pol_B_exo1 PF03104.14 CDI87412.1 - 3.8e-05 22.7 0.0 0.0078 15.1 0.0 2.3 2 0 0 2 2 2 2 DNA polymerase family B, exonuclease domain DUF1590 PF07629.6 CDI87413.1 - 0.0086 15.6 0.3 1.9 8.1 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1590) PhyH PF05721.8 CDI87415.1 - 1.3e-10 41.6 0.1 2.5e-09 37.5 0.0 2.9 2 1 0 2 2 2 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_3 PF13640.1 CDI87415.1 - 0.023 15.2 0.0 0.049 14.1 0.0 1.5 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Peptidase_C2 PF00648.16 CDI87417.1 - 4.3e-25 88.3 0.2 2.6e-24 85.7 0.0 2.0 2 0 0 2 2 2 1 Calpain family cysteine protease AP2 PF00847.15 CDI87418.1 - 7.5e-14 51.6 3.2 3.7e-10 39.7 0.1 2.6 2 0 0 2 2 2 2 AP2 domain ACDC PF14733.1 CDI87418.1 - 0.00062 19.8 0.0 0.0019 18.2 0.0 1.8 1 0 0 1 1 1 1 AP2-coincident C-terminal FtsJ PF01728.14 CDI87419.1 - 2.1e-53 181.0 0.0 2.7e-53 180.6 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase NSP13 PF06460.7 CDI87419.1 - 0.00067 18.6 0.0 0.00087 18.2 0.0 1.1 1 0 0 1 1 1 1 Coronavirus NSP13 Methyltransf_31 PF13847.1 CDI87419.1 - 0.0031 17.0 0.0 0.064 12.8 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CDI87419.1 - 0.0077 15.9 0.0 0.013 15.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain 2Fe-2S_Ferredox PF11591.3 CDI87419.1 - 0.43 10.2 3.0 0.28 10.8 0.2 2.1 3 0 0 3 3 3 0 Ferredoxin chloroplastic transit peptide NUDIX_2 PF13869.1 CDI87420.1 - 1e-54 184.7 0.0 1.4e-54 184.3 0.0 1.1 1 0 0 1 1 1 1 Nucleotide hydrolase WD40 PF00400.27 CDI87421.1 - 5.1e-13 48.3 19.9 0.011 15.5 0.0 10.8 10 0 0 10 10 10 5 WD domain, G-beta repeat Receptor_IA-2 PF11548.3 CDI87421.1 - 0.014 15.2 0.0 0.034 14.0 0.0 1.5 1 0 0 1 1 1 0 Protein-tyrosine phosphatase receptor IA-2 DUF605 PF04652.11 CDI87422.1 - 0.0036 16.7 31.6 0.011 15.1 10.4 2.2 2 0 0 2 2 2 2 Vta1 like XAP5 PF04921.9 CDI87422.1 - 0.014 14.9 6.7 0.014 14.9 4.6 3.1 2 1 1 3 3 3 0 XAP5, circadian clock regulator SDA1 PF05285.7 CDI87422.1 - 0.016 14.4 30.9 0.033 13.4 8.4 2.2 2 0 0 2 2 2 0 SDA1 SprA-related PF12118.3 CDI87422.1 - 0.068 12.4 42.8 0.046 13.0 20.1 2.1 2 0 0 2 2 2 0 SprA-related family Zip PF02535.17 CDI87422.1 - 0.51 9.2 13.7 0.088 11.7 1.0 2.3 2 0 0 2 2 2 0 ZIP Zinc transporter MRP-S31 PF15433.1 CDI87422.1 - 1.6 8.0 27.7 0.13 11.7 12.9 2.1 2 0 0 2 2 2 0 Mitochondrial 28S ribosomal protein S31 EIIBC-GUT_N PF03612.9 CDI87422.1 - 2.4 7.7 19.6 0.04 13.5 3.0 2.9 3 0 0 3 3 3 0 Sorbitol phosphotransferase enzyme II N-terminus GET2 PF08690.5 CDI87422.1 - 2.7 7.1 27.7 0.054 12.7 12.1 2.1 2 0 0 2 2 2 0 GET complex subunit GET2 DUF1510 PF07423.6 CDI87422.1 - 3.5 6.9 38.3 0.39 10.0 3.5 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1510) Utp14 PF04615.8 CDI87422.1 - 7.9 4.5 35.4 3 5.8 5.2 2.1 2 0 0 2 2 2 0 Utp14 protein Suf PF05843.9 CDI87426.1 - 0.00088 19.0 4.2 0.0015 18.3 2.9 1.4 1 0 0 1 1 1 1 Suppressor of forked protein (Suf) PAT1 PF09770.4 CDI87426.1 - 0.0092 14.2 22.3 0.014 13.7 15.5 1.2 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 FHIPEP PF00771.15 CDI87426.1 - 0.033 12.5 1.6 0.16 10.2 0.2 2.3 3 0 0 3 3 3 0 FHIPEP family DUF1183 PF06682.7 CDI87426.1 - 0.082 12.4 4.3 12 5.3 3.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1183) Spt20 PF12090.3 CDI87426.1 - 0.12 11.6 7.1 0.25 10.6 4.9 1.5 1 0 0 1 1 1 0 Spt20 family FCP1_C PF09309.5 CDI87426.1 - 0.15 11.3 8.0 0.47 9.7 5.5 1.9 1 0 0 1 1 1 0 FCP1, C-terminal DUF1669 PF07894.7 CDI87426.1 - 0.37 9.9 7.1 0.63 9.1 4.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1669) Pex14_N PF04695.8 CDI87426.1 - 0.83 9.7 15.1 0.086 12.8 6.8 2.0 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Hid1 PF12722.2 CDI87426.1 - 1.8 6.1 5.1 2.9 5.4 3.5 1.3 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Serinc PF03348.10 CDI87426.1 - 3.6 6.1 5.3 7.7 5.0 3.7 1.5 1 0 0 1 1 1 0 Serine incorporator (Serinc) UPF0560 PF10577.4 CDI87426.1 - 5 5.2 13.2 7.6 4.6 9.1 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Pex16 PF08610.5 CDI87426.1 - 5.3 5.9 7.5 9.5 5.1 5.2 1.3 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) FLO_LFY PF01698.11 CDI87428.1 - 0.046 12.5 12.0 0.056 12.2 8.3 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein MRP-S31 PF15433.1 CDI87428.1 - 0.067 12.6 19.5 0.1 12.0 13.5 1.3 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 AvrE PF11725.3 CDI87428.1 - 0.21 8.5 20.3 0.25 8.3 14.1 1.0 1 0 0 1 1 1 0 Pathogenicity factor FAM60A PF15396.1 CDI87428.1 - 0.36 10.5 8.2 0.46 10.1 5.7 1.3 1 0 0 1 1 1 0 Protein Family FAM60A Serinc PF03348.10 CDI87428.1 - 1.3 7.6 8.8 1.6 7.3 6.1 1.3 1 0 0 1 1 1 0 Serine incorporator (Serinc) Hid1 PF12722.2 CDI87428.1 - 2.1 5.9 12.8 2.3 5.7 8.9 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein AUX_IAA PF02309.11 CDI87428.1 - 3.8 7.1 11.0 5.7 6.6 7.6 1.3 1 0 0 1 1 1 0 AUX/IAA family Spore_YhcN_YlaJ PF09580.5 CDI87428.1 - 4.4 7.3 13.8 5.9 6.9 9.6 1.3 1 0 0 1 1 1 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) TFIIA PF03153.8 CDI87428.1 - 5.3 6.8 51.6 8 6.2 35.8 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Baculo_PP31 PF05311.6 CDI87428.1 - 8.9 5.4 14.8 14 4.8 10.3 1.2 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) DUF1183 PF06682.7 CDI87429.1 - 0.017 14.7 0.9 0.017 14.7 0.7 6.7 3 2 2 6 6 6 0 Protein of unknown function (DUF1183) DUF1510 PF07423.6 CDI87429.1 - 0.11 11.8 0.0 0.11 11.8 0.0 6.7 5 1 2 7 7 7 0 Protein of unknown function (DUF1510) SUFU_C PF12470.3 CDI87430.1 - 0.095 12.2 3.7 0.12 12.0 2.6 1.1 1 0 0 1 1 1 0 Suppressor of Fused Gli/Ci N terminal binding domain CDC45 PF02724.9 CDI87430.1 - 0.22 9.5 9.1 0.26 9.2 6.3 1.0 1 0 0 1 1 1 0 CDC45-like protein Striatin PF08232.7 CDI87430.1 - 0.52 10.6 7.3 0.65 10.3 5.0 1.1 1 0 0 1 1 1 0 Striatin family Filo_glycop PF01611.11 CDI87430.1 - 0.52 9.0 7.2 0.61 8.8 5.0 1.0 1 0 0 1 1 1 0 Filovirus glycoprotein DUF3449 PF11931.3 CDI87430.1 - 0.63 9.5 3.1 0.94 8.9 2.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3449) FAM60A PF15396.1 CDI87430.1 - 1.6 8.4 12.1 2 8.1 8.4 1.1 1 0 0 1 1 1 0 Protein Family FAM60A Apc15p PF05841.6 CDI87430.1 - 2 9.1 16.3 3.1 8.5 11.3 1.3 1 0 0 1 1 1 0 Apc15p protein Uds1 PF15456.1 CDI87430.1 - 2.5 8.1 6.9 3.7 7.5 4.8 1.3 1 0 0 1 1 1 0 Up-regulated During Septation RP-C_C PF11800.3 CDI87430.1 - 3.1 7.4 6.5 3.1 7.4 4.5 1.1 1 0 0 1 1 1 0 Replication protein C C-terminal region Bul1_C PF04426.7 CDI87430.1 - 5.8 6.0 14.8 8.8 5.4 10.2 1.2 1 0 0 1 1 1 0 Bul1 C terminus MAP65_ASE1 PF03999.7 CDI87430.1 - 5.9 5.3 19.4 7.1 5.0 13.5 1.0 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) Rtf2 PF04641.7 CDI87430.1 - 6.7 5.8 8.3 7.9 5.5 5.7 1.0 1 0 0 1 1 1 0 Rtf2 RING-finger Herpes_DNAp_acc PF04929.7 CDI87430.1 - 7.9 5.3 12.7 9.4 5.0 8.8 1.0 1 0 0 1 1 1 0 Herpes DNA replication accessory factor DUF2216 PF10226.4 CDI87430.1 - 8.3 5.8 12.7 10 5.5 8.8 1.1 1 0 0 1 1 1 0 Uncharacterized conserved proteins (DUF2216) DNA_pol_viral_N PF00242.12 CDI87430.1 - 8.3 5.3 21.4 9.4 5.1 14.8 1.0 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain DUF4482 PF14818.1 CDI87430.1 - 8.9 6.9 10.5 10 6.7 7.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4482) Apt1 PF10351.4 CDI87430.1 - 9.5 4.9 24.1 11 4.7 16.7 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF3371 PF11851.3 CDI87433.1 - 3.9 8.1 34.0 3.5 8.3 8.7 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3371) UPF0086 PF01868.11 CDI87436.1 - 1.5e-06 27.7 0.0 4.1e-06 26.3 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function UPF0086 DUF2235 PF09994.4 CDI87436.1 - 0.012 14.9 0.4 0.021 14.1 0.2 1.4 1 0 0 1 1 1 0 Uncharacterized alpha/beta hydrolase domain (DUF2235) Tetraspannin PF00335.15 CDI87436.1 - 5.7 6.1 5.7 11 5.2 3.9 1.5 1 0 0 1 1 1 0 Tetraspanin family Paramyxo_ncap PF00973.14 CDI87436.1 - 8.2 4.9 8.8 15 4.1 6.1 1.3 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein DUF4159 PF13709.1 CDI87436.1 - 8.2 5.4 7.3 2 7.4 1.7 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4159) DUF945 PF06097.6 CDI87437.1 - 0.0067 15.2 4.7 0.011 14.5 3.3 1.3 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF945) DUF572 PF04502.8 CDI87437.1 - 0.065 12.4 13.8 0.089 11.9 9.6 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF4199 PF13858.1 CDI87437.1 - 0.22 11.4 1.2 0.4 10.5 0.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) DUF4613 PF15390.1 CDI87437.1 - 0.31 9.1 10.1 0.38 8.8 7.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) DUF4175 PF13779.1 CDI87437.1 - 0.36 8.4 23.9 0.62 7.6 16.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) PAT1 PF09770.4 CDI87437.1 - 0.4 8.8 20.3 0.54 8.4 14.1 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Ribosomal_60s PF00428.14 CDI87437.1 - 0.73 10.2 30.7 0.42 11.0 5.3 3.9 4 0 0 4 4 4 0 60s Acidic ribosomal protein Spore_coat_CotO PF14153.1 CDI87437.1 - 0.89 8.9 13.1 1.6 8.1 9.1 1.3 1 0 0 1 1 1 0 Spore coat protein CotO DUF4557 PF15101.1 CDI87437.1 - 0.9 9.3 15.6 1.7 8.4 10.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) RED_N PF07808.8 CDI87437.1 - 0.91 8.6 12.5 1.6 7.9 8.6 1.3 1 0 0 1 1 1 0 RED-like protein N-terminal region Plasmodium_Vir PF05795.6 CDI87437.1 - 1.3 8.1 8.2 2.3 7.3 5.7 1.4 1 0 0 1 1 1 0 Plasmodium vivax Vir protein TFIIF_alpha PF05793.7 CDI87437.1 - 1.4 7.2 11.6 1.8 6.8 8.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Neur_chan_memb PF02932.11 CDI87437.1 - 2.4 7.9 6.3 3.6 7.4 4.4 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Ndc1_Nup PF09531.5 CDI87437.1 - 3.1 6.1 20.3 4.1 5.6 14.0 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Spc7_N PF15402.1 CDI87437.1 - 8.6 4.2 28.1 12 3.7 19.5 1.1 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 DUF4079 PF13301.1 CDI87438.1 - 0.038 13.9 3.3 0.043 13.8 2.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4079) DUF605 PF04652.11 CDI87438.1 - 0.32 10.3 6.1 0.33 10.3 4.2 1.1 1 0 0 1 1 1 0 Vta1 like CD20 PF04103.10 CDI87438.1 - 1.1 9.1 3.9 3.2 7.6 2.7 1.7 1 1 0 1 1 1 0 CD20-like family Fucose_iso_N2 PF07882.7 CDI87438.1 - 1.2 8.7 4.7 1.6 8.3 3.3 1.3 1 0 0 1 1 1 0 L-fucose isomerase, second N-terminal domain GET2 PF08690.5 CDI87438.1 - 1.9 7.6 11.6 2 7.5 8.0 1.0 1 0 0 1 1 1 0 GET complex subunit GET2 PMC2NT PF08066.7 CDI87438.1 - 2.4 8.5 5.3 3.4 8.0 3.6 1.4 1 1 0 1 1 1 0 PMC2NT (NUC016) domain DUF106 PF01956.11 CDI87438.1 - 4.6 6.7 10.3 4.8 6.6 7.1 1.0 1 0 0 1 1 1 0 Integral membrane protein DUF106 DUF912 PF06024.7 CDI87438.1 - 4.7 7.3 6.6 3.5 7.7 0.4 2.0 1 1 1 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) SUI1 PF01253.17 CDI87441.1 - 3e-15 55.7 0.1 7.5e-15 54.5 0.0 1.7 1 0 0 1 1 1 1 Translation initiation factor SUI1 Cation_ATPase_N PF00690.21 CDI87442.1 - 0.032 13.6 0.2 0.2 11.1 0.0 2.2 2 0 0 2 2 2 0 Cation transporter/ATPase, N-terminus TLD PF07534.11 CDI87443.1 - 6.1e-21 74.8 0.0 5.9e-20 71.6 0.0 2.0 2 0 0 2 2 2 1 TLD ACC_epsilon PF13822.1 CDI87443.1 - 0.22 11.9 1.5 0.41 11.0 1.1 1.4 1 0 0 1 1 1 0 Acyl-CoA carboxylase epsilon subunit Ribosomal_L29 PF00831.18 CDI87444.1 - 3.7e-17 61.7 2.6 3.7e-17 61.7 1.8 1.8 2 1 0 2 2 2 1 Ribosomal L29 protein LURAP PF14854.1 CDI87444.1 - 0.17 11.5 0.8 0.34 10.6 0.6 1.6 1 1 0 1 1 1 0 Leucine rich adaptor protein SRP_SPB PF02978.14 CDI87444.1 - 0.58 10.4 5.9 6.2 7.1 1.3 2.2 2 0 0 2 2 2 0 Signal peptide binding domain MRP-L47 PF06984.8 CDI87444.1 - 0.83 9.6 5.7 0.17 11.8 0.6 2.2 2 2 1 3 3 3 0 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) DUF4019 PF13211.1 CDI87444.1 - 3 8.1 6.1 2.3 8.5 2.6 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF4019) Dynein_heavy PF03028.10 CDI87445.1 - 6.2e-155 517.0 0.0 2.7e-154 514.9 0.0 2.0 1 1 0 1 1 1 1 Dynein heavy chain and region D6 of dynein motor DHC_N1 PF08385.7 CDI87445.1 - 6.2e-148 493.7 0.6 6.2e-148 493.7 0.4 4.3 5 0 0 5 5 5 1 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.8 CDI87445.1 - 2.1e-127 425.0 2.6 2.1e-127 425.0 1.8 3.0 2 0 0 2 2 2 1 Dynein heavy chain, N-terminal region 2 AAA_6 PF12774.2 CDI87445.1 - 1.7e-80 269.8 0.0 6e-80 268.0 0.0 1.9 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region D1 AAA_9 PF12781.2 CDI87445.1 - 3.6e-42 143.7 0.0 7.5e-42 142.7 0.0 1.5 1 0 0 1 1 1 1 ATP-binding dynein motor region D5 AAA_8 PF12780.2 CDI87445.1 - 1.2e-37 129.3 0.0 1.4e-35 122.5 0.0 2.6 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 AAA_5 PF07728.9 CDI87445.1 - 8.8e-32 109.7 0.0 5.3e-11 42.3 0.0 6.3 4 1 0 4 4 4 4 AAA domain (dynein-related subfamily) MT PF12777.2 CDI87445.1 - 9.4e-29 100.2 10.5 1.6e-28 99.4 7.3 1.4 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA PF00004.24 CDI87445.1 - 1.5e-15 57.5 0.2 0.0047 17.1 0.0 6.1 5 0 0 5 5 5 3 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.2 CDI87445.1 - 8.5e-15 54.5 0.1 2.2e-13 49.9 0.0 2.8 3 0 0 3 3 3 1 P-loop containing dynein motor region D3 AAA_22 PF13401.1 CDI87445.1 - 3.2e-13 49.9 0.7 0.00072 19.7 0.0 7.7 6 1 1 7 7 7 1 AAA domain AAA_19 PF13245.1 CDI87445.1 - 8.4e-07 28.6 0.2 0.19 11.5 0.0 4.9 4 0 0 4 4 4 1 Part of AAA domain AAA_17 PF13207.1 CDI87445.1 - 1.4e-06 29.1 0.0 4 8.2 0.0 5.5 4 0 0 4 4 4 1 AAA domain AAA_18 PF13238.1 CDI87445.1 - 0.0001 22.6 0.3 17 5.6 0.0 5.5 5 0 0 5 5 5 0 AAA domain Zeta_toxin PF06414.7 CDI87445.1 - 0.00012 21.1 0.5 0.087 11.9 0.0 4.2 5 0 0 5 5 5 1 Zeta toxin AAA_25 PF13481.1 CDI87445.1 - 0.00016 21.1 1.2 0.024 14.0 0.0 4.1 4 0 0 4 4 4 1 AAA domain AAA_14 PF13173.1 CDI87445.1 - 0.00037 20.4 0.0 2.8 7.8 0.0 4.6 5 0 0 5 5 4 1 AAA domain AAA_29 PF13555.1 CDI87445.1 - 0.0016 17.9 0.0 7.5 6.1 0.0 3.7 3 0 0 3 3 3 0 P-loop containing region of AAA domain AAA_33 PF13671.1 CDI87445.1 - 0.0051 16.6 9.9 0.69 9.7 0.0 5.3 6 0 0 6 6 4 1 AAA domain ResIII PF04851.10 CDI87445.1 - 0.014 15.2 2.8 3.6 7.3 0.0 4.7 5 0 0 5 5 4 0 Type III restriction enzyme, res subunit RNA_helicase PF00910.17 CDI87445.1 - 0.018 15.2 0.1 1e+02 3.1 0.0 4.7 4 0 0 4 4 4 0 RNA helicase Reo_sigmaC PF04582.7 CDI87445.1 - 0.047 12.8 3.2 2.4 7.2 0.4 3.0 2 0 0 2 2 2 0 Reovirus sigma C capsid protein Mg_chelatase PF01078.16 CDI87445.1 - 0.05 12.7 7.6 5.3 6.1 0.0 4.6 4 1 1 5 5 5 0 Magnesium chelatase, subunit ChlI Atg14 PF10186.4 CDI87445.1 - 2.2 7.1 21.8 0.68 8.8 4.3 3.2 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 GAGA_bind PF06217.7 CDI87446.1 - 9.4e-06 25.8 55.0 0.0013 18.7 11.3 2.1 2 0 0 2 2 2 2 GAGA binding protein-like family SAGA-Tad1 PF12767.2 CDI87446.1 - 1.8e-05 24.5 58.6 0.011 15.4 21.9 2.1 2 0 0 2 2 2 2 Transcriptional regulator of RNA polII, SAGA, subunit Ycf1 PF05758.7 CDI87446.1 - 0.00042 18.2 16.3 0.00042 18.2 11.3 2.1 2 0 0 2 2 2 1 Ycf1 Suf PF05843.9 CDI87446.1 - 0.0018 18.0 25.9 0.0018 18.0 18.0 3.1 2 1 1 3 3 1 1 Suppressor of forked protein (Suf) SMN PF06003.7 CDI87446.1 - 0.002 17.3 1.1 0.002 17.3 0.8 2.6 2 1 0 2 2 1 1 Survival motor neuron protein (SMN) Presenilin PF01080.12 CDI87446.1 - 0.002 17.0 12.0 0.002 17.0 8.3 2.3 2 0 0 2 2 2 1 Presenilin DUF4045 PF13254.1 CDI87446.1 - 0.021 14.1 52.7 0.1 11.8 17.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4045) SAPS PF04499.10 CDI87446.1 - 0.022 13.4 52.2 0.0056 15.3 15.1 2.1 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein Neur_chan_memb PF02932.11 CDI87446.1 - 0.036 13.9 47.7 0.061 13.2 9.5 2.4 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region CDC27 PF09507.5 CDI87446.1 - 0.075 12.2 57.9 0.31 10.2 11.9 2.3 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 Hid1 PF12722.2 CDI87446.1 - 0.088 10.4 67.9 0.012 13.3 14.0 2.0 2 0 0 2 2 2 0 High-temperature-induced dauer-formation protein PAT1 PF09770.4 CDI87446.1 - 0.11 10.6 133.3 0.4 8.8 34.5 2.1 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 DUF1510 PF07423.6 CDI87446.1 - 0.12 11.7 67.3 0.54 9.5 22.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) SOBP PF15279.1 CDI87446.1 - 0.17 12.2 59.8 0.024 15.0 13.6 2.4 2 0 0 2 2 2 0 Sine oculis-binding protein SPX PF03105.14 CDI87446.1 - 0.23 11.2 58.0 0.021 14.5 10.6 2.2 2 0 0 2 2 2 0 SPX domain PLRV_ORF5 PF01690.12 CDI87446.1 - 0.46 9.5 54.3 0.061 12.4 10.0 2.1 2 0 0 2 2 2 0 Potato leaf roll virus readthrough protein Raftlin PF15250.1 CDI87446.1 - 0.49 8.8 52.2 0.52 8.7 16.6 2.2 2 0 0 2 2 2 0 Raftlin Utp14 PF04615.8 CDI87446.1 - 1.1 7.3 76.0 0.067 11.3 23.9 2.1 2 0 0 2 2 2 0 Utp14 protein LMBR1 PF04791.11 CDI87446.1 - 4.4 5.7 31.1 0.72 8.3 6.4 2.2 2 0 0 2 2 2 0 LMBR1-like membrane protein DUF4647 PF15504.1 CDI87446.1 - 4.6 5.9 75.0 0.41 9.4 19.7 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4647) DUF572 PF04502.8 CDI87446.1 - 6.4 5.8 65.2 6 5.9 17.3 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF572) Draxin PF15550.1 CDI87446.1 - 7.6 6.0 53.7 0.85 9.2 15.4 2.6 3 0 0 3 3 3 0 Draxin SR-25 PF10500.4 CDI87447.1 - 0.00098 18.6 31.7 0.00098 18.6 22.0 2.9 1 1 1 2 2 2 1 Nuclear RNA-splicing-associated protein Trypan_PARP PF05887.6 CDI87447.1 - 0.84 9.4 7.2 1.5 8.6 5.0 1.5 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Herpes_UL87 PF03043.9 CDI87448.1 - 3.7 5.8 37.3 0.0066 14.8 6.5 3.5 1 1 2 3 3 3 0 Herpesvirus UL87 family Topoisom_I_N PF02919.10 CDI87449.1 - 4.6e-14 52.2 0.3 1e-13 51.1 0.1 1.6 2 0 0 2 2 2 1 Eukaryotic DNA topoisomerase I, DNA binding fragment SART-1 PF03343.8 CDI87449.1 - 0.031 12.6 4.3 0.0095 14.3 0.9 1.5 1 1 1 2 2 2 0 SART-1 family Nop14 PF04147.7 CDI87449.1 - 1.6 6.5 7.2 2.1 6.1 5.0 1.2 1 0 0 1 1 1 0 Nop14-like family CytochromB561_N PF09786.4 CDI87449.1 - 4.2 5.7 16.6 5.2 5.3 11.5 1.0 1 0 0 1 1 1 0 Cytochrome B561, N terminal Mito_carr PF00153.22 CDI87451.1 - 0.085 12.5 0.1 0.085 12.5 0.1 5.5 5 1 0 5 5 5 0 Mitochondrial carrier protein DUF819 PF05684.7 CDI87453.1 - 7.4 5.2 8.1 0.39 9.4 1.3 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF819) Med15 PF09606.5 CDI87458.1 - 2.2e-07 29.5 151.2 0.0039 15.4 55.8 4.5 4 0 0 4 4 4 4 ARC105 or Med15 subunit of Mediator complex non-fungal AAA_11 PF13086.1 CDI87458.1 - 6.6 6.2 38.9 0.82 9.1 10.4 4.5 5 0 0 5 5 5 0 AAA domain CDC45 PF02724.9 CDI87459.1 - 2.1 6.2 10.4 2.6 5.9 7.2 1.2 1 0 0 1 1 1 0 CDC45-like protein Hid1 PF12722.2 CDI87459.1 - 7.2 4.1 10.7 7.3 4.1 7.4 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Herpes_LMP1 PF05297.6 CDI87460.1 - 8 5.2 8.7 0.12 11.2 0.5 1.9 2 1 0 2 2 2 0 Herpesvirus latent membrane protein 1 (LMP1) SR-25 PF10500.4 CDI87462.1 - 2.7e-05 23.7 14.3 2.7e-05 23.7 9.9 11.3 8 4 2 11 11 11 2 Nuclear RNA-splicing-associated protein DUF3801 PF12687.2 CDI87462.1 - 0.028 14.0 0.1 0.028 14.0 0.1 6.5 6 1 0 6 6 6 0 Protein of unknown function (DUF3801) WD40 PF00400.27 CDI87463.1 - 1.8e-13 49.7 7.5 5.4e-06 26.0 0.0 7.1 7 0 0 7 7 7 3 WD domain, G-beta repeat SR-25 PF10500.4 CDI87463.1 - 0.0004 19.9 9.7 0.0004 19.9 6.7 9.8 9 2 0 10 10 10 3 Nuclear RNA-splicing-associated protein Plasmodium_Vir PF05795.6 CDI87464.1 - 3.1 6.9 5.6 4 6.5 3.9 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein DUF566 PF04484.7 CDI87464.1 - 3.4 7.0 13.3 4 6.8 9.2 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF566) Rer1 PF03248.8 CDI87465.1 - 2.9e-61 206.1 4.1 3.7e-61 205.7 2.8 1.1 1 0 0 1 1 1 1 Rer1 family Bromodomain PF00439.20 CDI87466.1 - 2.6e-33 113.7 0.0 6.7e-19 67.5 0.0 2.4 2 0 0 2 2 2 2 Bromodomain NICE-3 PF07406.6 CDI87466.1 - 0.11 11.9 1.1 0.22 10.9 0.7 1.4 1 0 0 1 1 1 0 NICE-3 protein V_ATPase_I PF01496.14 CDI87466.1 - 1.7 6.4 5.1 2.6 5.8 3.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF3573 PF12097.3 CDI87466.1 - 2.1 6.8 3.1 3.8 6.0 2.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) DUF726 PF05277.7 CDI87467.1 - 2.8e-59 200.7 4.6 1.1e-30 106.7 0.0 2.7 2 1 1 3 3 3 2 Protein of unknown function (DUF726) tRNA-synt_2b PF00587.20 CDI87469.1 - 9.7e-21 74.1 0.2 1.5e-20 73.5 0.1 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA_edit PF04073.10 CDI87469.1 - 4.5e-20 71.7 0.1 7.9e-20 70.9 0.0 1.4 1 0 0 1 1 1 1 Aminoacyl-tRNA editing domain HGTP_anticodon PF03129.15 CDI87469.1 - 0.019 14.9 0.1 0.065 13.1 0.0 1.9 2 0 0 2 2 2 0 Anticodon binding domain SR-25 PF10500.4 CDI87469.1 - 0.037 13.4 6.8 0.071 12.5 4.7 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Ribosomal_60s PF00428.14 CDI87469.1 - 0.37 11.2 6.4 0.27 11.6 2.0 2.3 2 0 0 2 2 2 0 60s Acidic ribosomal protein DUF908 PF06012.7 CDI87472.1 - 9.5e-12 44.8 2.6 9.5e-12 44.8 1.8 5.5 3 3 2 5 5 5 2 Domain of Unknown Function (DUF908) SAPS PF04499.10 CDI87472.1 - 9.2 4.7 47.0 0.76 8.3 3.6 3.9 4 0 0 4 4 4 0 SIT4 phosphatase-associated protein Ribosomal_L7Ae PF01248.21 CDI87473.1 - 1.4e-26 91.7 0.4 1.9e-26 91.4 0.3 1.2 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family SpoU_sub_bind PF08032.7 CDI87473.1 - 0.024 14.8 0.0 0.045 13.9 0.0 1.5 1 0 0 1 1 1 0 RNA 2'-O ribose methyltransferase substrate binding TFIIA PF03153.8 CDI87474.1 - 0.26 11.1 18.7 0.32 10.8 13.0 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PIG-U PF06728.8 CDI87474.1 - 0.29 9.9 1.7 0.35 9.6 1.1 1.1 1 0 0 1 1 1 0 GPI transamidase subunit PIG-U IER PF05760.7 CDI87474.1 - 0.69 9.7 17.5 0.83 9.5 12.1 1.0 1 0 0 1 1 1 0 Immediate early response protein (IER) Med15 PF09606.5 CDI87477.1 - 0.0032 15.7 31.8 0.0036 15.5 22.1 1.0 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal Spt20 PF12090.3 CDI87477.1 - 0.0068 15.7 3.0 0.0068 15.7 2.1 1.1 1 0 0 1 1 1 1 Spt20 family RAB3GAP2_N PF14655.1 CDI87477.1 - 0.018 14.0 3.9 0.018 14.0 2.7 1.2 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Suf PF05843.9 CDI87477.1 - 0.025 14.3 4.8 0.024 14.3 3.3 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Tub PF01167.13 CDI87477.1 - 0.028 13.4 0.2 0.033 13.1 0.2 1.1 1 0 0 1 1 1 0 Tub family PAT1 PF09770.4 CDI87477.1 - 0.034 12.4 15.3 0.034 12.4 10.6 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DivIC PF04977.10 CDI87477.1 - 0.17 11.3 11.3 0.24 10.9 7.8 1.2 1 0 0 1 1 1 0 Septum formation initiator Serinc PF03348.10 CDI87477.1 - 0.2 10.3 3.4 0.2 10.2 2.4 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) Peptidase_S15 PF02129.13 CDI87477.1 - 0.2 11.0 7.0 0.25 10.7 4.8 1.2 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) DUF4557 PF15101.1 CDI87477.1 - 0.23 11.2 8.1 0.24 11.2 5.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) DUF1764 PF08576.5 CDI87477.1 - 0.45 11.3 6.5 0.7 10.7 4.5 1.3 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) DUF4050 PF13259.1 CDI87477.1 - 0.54 10.1 6.9 0.78 9.6 4.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4050) TFIIA PF03153.8 CDI87477.1 - 0.72 9.6 17.1 0.79 9.5 11.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF2232 PF09991.4 CDI87477.1 - 0.73 8.7 3.7 0.97 8.3 2.6 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) DUF3450 PF11932.3 CDI87477.1 - 0.73 9.0 17.2 1.1 8.4 11.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) FHIPEP PF00771.15 CDI87477.1 - 1.2 7.4 8.1 1.2 7.3 5.6 1.0 1 0 0 1 1 1 0 FHIPEP family Phage_portal PF04860.7 CDI87477.1 - 1.7 7.1 7.9 1.7 7.2 4.9 1.4 1 1 0 1 1 1 0 Phage portal protein Glt_symporter PF03616.9 CDI87477.1 - 2 6.8 6.2 2.5 6.4 4.3 1.1 1 0 0 1 1 1 0 Sodium/glutamate symporter DOR PF14839.1 CDI87477.1 - 2.4 7.8 11.1 2.8 7.6 7.7 1.2 1 0 0 1 1 1 0 DOR family DUF2894 PF11445.3 CDI87477.1 - 2.7 8.2 14.2 3.1 8.0 9.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2894) HemX PF04375.9 CDI87477.1 - 4.2 5.8 24.3 5.2 5.5 16.8 1.1 1 0 0 1 1 1 0 HemX ABC_tran_2 PF12848.2 CDI87477.1 - 4.3 7.2 21.9 8.9 6.2 15.2 1.4 1 0 0 1 1 1 0 ABC transporter Activator_LAG-3 PF11498.3 CDI87477.1 - 4.3 5.9 27.1 5.1 5.7 18.8 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Helicase_RecD PF05127.9 CDI87477.1 - 8.4 5.9 9.6 4.4 6.9 5.6 1.3 1 1 0 1 1 1 0 Helicase PAT1 PF09770.4 CDI87478.1 - 5.3e-05 21.6 55.1 0.0016 16.8 14.8 2.1 2 0 0 2 2 2 2 Topoisomerase II-associated protein PAT1 DUF3801 PF12687.2 CDI87478.1 - 0.0029 17.2 2.2 0.0029 17.2 1.5 3.1 2 1 0 2 2 1 1 Protein of unknown function (DUF3801) Herpes_UL87 PF03043.9 CDI87478.1 - 0.004 15.6 4.9 0.0096 14.3 3.4 1.6 1 1 0 1 1 1 1 Herpesvirus UL87 family Ribosomal_60s PF00428.14 CDI87478.1 - 0.023 15.0 3.5 0.023 15.0 2.4 4.1 4 1 0 4 4 3 0 60s Acidic ribosomal protein Anoctamin PF04547.7 CDI87478.1 - 0.029 13.0 11.1 0.69 8.5 0.2 2.1 2 0 0 2 2 2 0 Calcium-activated chloride channel FAM60A PF15396.1 CDI87478.1 - 0.087 12.5 23.1 0.11 12.1 5.6 2.1 2 0 0 2 2 2 0 Protein Family FAM60A DDHD PF02862.12 CDI87478.1 - 0.22 11.3 21.2 0.37 10.5 2.0 2.4 2 0 0 2 2 2 0 DDHD domain Hid1 PF12722.2 CDI87478.1 - 0.58 7.7 28.6 0.85 7.2 9.9 2.1 2 0 0 2 2 2 0 High-temperature-induced dauer-formation protein DUF572 PF04502.8 CDI87478.1 - 0.6 9.2 27.5 0.094 11.9 7.8 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF572) Sporozoite_P67 PF05642.6 CDI87478.1 - 0.62 7.8 16.3 0.03 12.2 3.5 2.4 2 0 0 2 2 2 0 Sporozoite P67 surface antigen Cyto_heme_lyase PF01265.12 CDI87478.1 - 0.99 8.9 25.6 0.21 11.1 6.7 2.2 2 0 0 2 2 2 0 Cytochrome c/c1 heme lyase AUX_IAA PF02309.11 CDI87478.1 - 1.1 9.0 19.1 1.7 8.3 5.4 2.3 2 0 0 2 2 2 0 AUX/IAA family DUF1510 PF07423.6 CDI87478.1 - 1.6 8.0 37.4 2.3 7.5 7.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) TFIIF_alpha PF05793.7 CDI87478.1 - 3.2 6.0 24.1 0.11 10.8 6.2 2.1 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Zip PF02535.17 CDI87478.1 - 4.7 6.1 9.5 0.95 8.4 2.0 2.2 2 0 0 2 2 2 0 ZIP Zinc transporter GPCR_chapero_1 PF11904.3 CDI87478.1 - 4.7 6.2 23.4 0.78 8.8 2.5 2.1 2 0 0 2 2 2 0 GPCR-chaperone CDC45 PF02724.9 CDI87478.1 - 7.1 4.5 28.6 1.1 7.1 8.7 2.1 2 0 0 2 2 2 0 CDC45-like protein Neur_chan_memb PF02932.11 CDI87478.1 - 7.2 6.4 28.0 1.2 9.0 3.6 2.6 3 0 0 3 3 3 0 Neurotransmitter-gated ion-channel transmembrane region Conotoxin PF02950.12 CDI87480.1 - 0.016 15.9 5.0 0.016 15.9 3.5 2.5 2 0 0 2 2 2 0 Conotoxin PIG-U PF06728.8 CDI87480.1 - 0.02 13.7 0.0 0.041 12.7 0.0 1.5 1 0 0 1 1 1 0 GPI transamidase subunit PIG-U PLRV_ORF5 PF01690.12 CDI87480.1 - 0.12 11.4 13.5 0.15 11.1 9.3 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein PigN PF04987.9 CDI87480.1 - 0.25 9.9 0.7 0.41 9.2 0.5 1.3 1 0 0 1 1 1 0 Phosphatidylinositolglycan class N (PIG-N) DUF4647 PF15504.1 CDI87480.1 - 0.47 9.2 14.9 0.65 8.7 10.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4647) WBS_methylT PF12589.3 CDI87480.1 - 0.71 10.4 16.8 2.2 8.8 0.0 2.4 2 0 0 2 2 2 0 Methyltransferase involved in Williams-Beuren syndrome FAM176 PF14851.1 CDI87480.1 - 0.73 9.5 4.7 0.53 9.9 1.8 1.8 2 0 0 2 2 2 0 FAM176 family DUF1764 PF08576.5 CDI87480.1 - 1.1 10.1 15.7 0.37 11.5 5.4 2.4 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF1764) Hid1 PF12722.2 CDI87480.1 - 1.2 6.6 11.1 1.6 6.2 7.7 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SAGA-Tad1 PF12767.2 CDI87480.1 - 1.6 8.3 16.5 5.1 6.6 7.8 2.1 2 0 0 2 2 2 0 Transcriptional regulator of RNA polII, SAGA, subunit COX6A PF02046.10 CDI87480.1 - 2.6 7.9 14.4 0.86 9.5 3.2 2.3 2 0 0 2 2 2 0 Cytochrome c oxidase subunit VIa Peptidase_S49_N PF08496.5 CDI87480.1 - 2.7 7.7 11.3 0.29 10.8 3.4 2.2 2 0 0 2 2 2 0 Peptidase family S49 N-terminal SID-1_RNA_chan PF13965.1 CDI87480.1 - 3 5.8 4.5 4.6 5.3 3.1 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Dala_Dala_lig_N PF01820.16 CDI87480.1 - 3.2 8.1 7.0 1.3 9.3 1.7 2.2 2 0 0 2 2 2 0 D-ala D-ala ligase N-terminus FimP PF09766.4 CDI87480.1 - 5.7 5.8 24.5 0.13 11.3 11.9 1.7 2 0 0 2 2 2 0 Fms-interacting protein Baculo_PP31 PF05311.6 CDI87480.1 - 5.9 6.0 17.4 1.9 7.7 7.3 2.1 2 0 0 2 2 2 0 Baculovirus 33KDa late protein (PP31) CD20 PF04103.10 CDI87480.1 - 6.2 6.7 6.5 1.8 8.4 0.8 2.4 2 1 1 3 3 3 0 CD20-like family Pex14_N PF04695.8 CDI87480.1 - 6.8 6.7 32.6 1.5 8.9 11.3 2.4 2 1 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF912 PF06024.7 CDI87480.1 - 7.4 6.6 10.6 1.3 9.0 2.9 2.3 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF4366 PF14283.1 CDI87480.1 - 7.8 5.8 14.6 6.9 6.0 1.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4366) ABC2_membrane_2 PF12679.2 CDI87480.1 - 7.8 5.2 11.1 1.3 7.8 1.3 2.0 2 0 0 2 2 2 0 ABC-2 family transporter protein FAM60A PF15396.1 CDI87480.1 - 7.8 6.1 12.9 0.98 9.1 3.6 2.0 2 0 0 2 2 2 0 Protein Family FAM60A OATP PF03137.15 CDI87480.1 - 9.2 4.1 9.2 0.89 7.5 3.3 1.5 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family MRP-S31 PF15433.1 CDI87480.1 - 9.3 5.5 21.8 0.11 11.8 5.2 2.2 2 0 0 2 2 2 0 Mitochondrial 28S ribosomal protein S31 AAA_23 PF13476.1 CDI87481.1 - 0.015 15.6 10.8 0.016 15.5 7.5 1.2 1 0 0 1 1 1 0 AAA domain DUF2232 PF09991.4 CDI87481.1 - 0.16 10.9 10.5 0.25 10.3 7.3 1.3 1 1 0 1 1 1 0 Predicted membrane protein (DUF2232) TraT PF05818.7 CDI87481.1 - 0.17 11.2 21.3 0.23 10.8 14.7 1.2 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein YfhO PF09586.5 CDI87481.1 - 0.4 8.6 8.1 0.45 8.4 5.6 1.2 1 0 0 1 1 1 0 Bacterial membrane protein YfhO Serinc PF03348.10 CDI87481.1 - 1 7.9 16.6 1.4 7.5 11.5 1.3 1 0 0 1 1 1 0 Serine incorporator (Serinc) Herpes_glycop PF01528.11 CDI87481.1 - 2.1 6.9 9.9 2.6 6.6 6.6 1.4 1 1 0 1 1 1 0 Herpesvirus glycoprotein M SprA-related PF12118.3 CDI87481.1 - 3.2 7.0 49.4 4.6 6.4 34.3 1.2 1 0 0 1 1 1 0 SprA-related family NMDAR2_C PF10565.4 CDI87481.1 - 3.4 6.2 20.1 3.9 6.0 13.9 1.0 1 0 0 1 1 1 0 N-methyl D-aspartate receptor 2B3 C-terminus Glyco_hydro_1 PF00232.13 CDI87481.1 - 4.2 5.4 10.3 5.2 5.1 7.2 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 1 BPL_N PF09825.4 CDI87481.1 - 9.2 4.9 10.6 10 4.8 7.3 1.2 1 0 0 1 1 1 0 Biotin-protein ligase, N terminal HNOBA PF07701.9 CDI87481.1 - 9.3 5.3 15.7 0.58 9.3 7.1 1.7 2 0 0 2 2 2 0 Heme NO binding associated APC_CDC26 PF10471.4 CDI87482.1 - 0.24 12.1 0.3 0.24 12.1 0.2 3.9 2 1 1 3 3 3 0 Anaphase-promoting complex APC subunit 1 DUF4207 PF13904.1 CDI87483.1 - 0.00093 18.6 51.5 0.00093 18.6 35.7 6.0 4 2 1 5 5 5 1 Domain of unknown function (DUF4207) Ribosomal_60s PF00428.14 CDI87483.1 - 0.019 15.3 8.1 0.019 15.3 5.6 9.6 8 3 2 10 10 10 0 60s Acidic ribosomal protein TrkA_N PF02254.13 CDI87484.1 - 9 6.3 9.8 3 7.8 4.0 2.1 1 1 0 1 1 1 0 TrkA-N domain Pex14_N PF04695.8 CDI87485.1 - 0.011 15.8 10.1 0.012 15.6 7.0 1.0 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Trypan_glycop_C PF10659.4 CDI87485.1 - 0.11 12.7 5.9 0.13 12.5 4.1 1.2 1 0 0 1 1 1 0 Trypanosome variant surface glycoprotein C-terminal domain PsbW PF07123.7 CDI87485.1 - 0.2 11.7 5.2 0.21 11.6 3.6 1.1 1 0 0 1 1 1 0 Photosystem II reaction centre W protein (PsbW) Apc15p PF05841.6 CDI87485.1 - 0.24 12.1 10.2 0.26 12.0 7.1 1.0 1 0 0 1 1 1 0 Apc15p protein DUF1183 PF06682.7 CDI87485.1 - 0.25 10.8 4.8 0.26 10.8 3.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) BRF1 PF07741.8 CDI87485.1 - 0.29 11.3 11.9 0.37 11.0 8.2 1.2 1 0 0 1 1 1 0 Brf1-like TBP-binding domain Gly-zipper_OmpA PF13436.1 CDI87485.1 - 0.36 10.5 10.5 0.44 10.2 7.2 1.1 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain DUF3371 PF11851.3 CDI87485.1 - 0.48 11.1 11.8 0.5 11.0 8.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3371) Ribosomal_60s PF00428.14 CDI87485.1 - 0.57 10.6 3.8 0.66 10.4 2.6 1.2 1 0 0 1 1 1 0 60s Acidic ribosomal protein Big_2 PF02368.13 CDI87485.1 - 0.68 9.8 6.6 0.85 9.5 4.6 1.2 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 2) FAM176 PF14851.1 CDI87485.1 - 0.69 9.5 4.1 0.76 9.4 2.9 1.0 1 0 0 1 1 1 0 FAM176 family UPF0560 PF10577.4 CDI87485.1 - 0.79 7.8 13.1 0.75 7.9 9.1 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Slp PF03843.8 CDI87485.1 - 0.81 8.6 6.7 0.99 8.3 4.6 1.1 1 0 0 1 1 1 0 Outer membrane lipoprotein Slp family DUF3729 PF12526.3 CDI87485.1 - 0.86 10.9 4.8 1 10.7 3.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3729) Pex16 PF08610.5 CDI87485.1 - 0.91 8.4 10.4 0.93 8.4 7.2 1.0 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) SeqA PF03925.8 CDI87485.1 - 1 9.0 8.0 1.1 8.9 5.5 1.1 1 0 0 1 1 1 0 SeqA protein Spt20 PF12090.3 CDI87485.1 - 1 8.6 11.0 1 8.6 7.6 1.2 1 0 0 1 1 1 0 Spt20 family DUF4242 PF14026.1 CDI87485.1 - 1.1 9.4 6.1 1.2 9.2 4.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF4242) FimP PF09766.4 CDI87485.1 - 1.1 8.2 15.5 1.1 8.2 10.7 1.1 1 0 0 1 1 1 0 Fms-interacting protein RED_N PF07808.8 CDI87485.1 - 1.3 8.2 11.5 1.2 8.3 8.0 1.2 1 0 0 1 1 1 0 RED-like protein N-terminal region FCP1_C PF09309.5 CDI87485.1 - 1.3 8.2 10.8 1.4 8.1 7.5 1.1 1 0 0 1 1 1 0 FCP1, C-terminal FAM91_C PF14648.1 CDI87485.1 - 1.7 7.3 5.4 1.7 7.3 3.7 1.0 1 0 0 1 1 1 0 FAM91 C-terminus DUF4512 PF14975.1 CDI87485.1 - 2 9.3 5.2 2.2 9.1 3.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4512) Suf PF05843.9 CDI87485.1 - 3 7.4 12.2 2.7 7.6 8.5 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF2413 PF10310.4 CDI87485.1 - 3.2 6.4 16.4 3.5 6.3 11.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) Folliculin PF11704.3 CDI87485.1 - 3.4 7.2 5.9 3.1 7.3 4.1 1.1 1 0 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport DUF1598 PF07643.6 CDI87485.1 - 3.4 7.7 9.8 3.8 7.6 6.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1598) SPARC_Ca_bdg PF10591.4 CDI87485.1 - 3.6 7.6 6.4 4.5 7.3 4.4 1.1 1 0 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region TraV PF09676.5 CDI87485.1 - 4.1 8.1 10.1 4.2 8.0 7.0 1.1 1 0 0 1 1 1 0 Type IV conjugative transfer system lipoprotein (TraV) Med15 PF09606.5 CDI87485.1 - 4.4 5.3 34.5 4.5 5.3 23.9 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Ctr PF04145.10 CDI87485.1 - 4.8 7.2 6.6 5.4 7.0 4.6 1.1 1 0 0 1 1 1 0 Ctr copper transporter family DUF1822 PF08852.6 CDI87485.1 - 4.9 5.8 14.9 5.5 5.6 10.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1822) DUF4557 PF15101.1 CDI87485.1 - 5 6.9 19.4 5.2 6.8 13.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) RAB3GAP2_N PF14655.1 CDI87485.1 - 5.4 5.9 10.1 4.9 6.0 7.0 1.2 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus DUF4647 PF15504.1 CDI87485.1 - 5.8 5.6 13.4 6.1 5.5 9.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4647) WES_acyltransf PF03007.11 CDI87485.1 - 6 6.3 7.8 6.5 6.2 5.4 1.1 1 0 0 1 1 1 0 Wax ester synthase-like Acyl-CoA acyltransferase domain Ndc1_Nup PF09531.5 CDI87485.1 - 6.6 5.0 9.8 6.5 5.0 6.8 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Band_3_cyto PF07565.8 CDI87485.1 - 6.8 6.1 8.3 6.4 6.2 5.7 1.0 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Bud13 PF09736.4 CDI87485.1 - 8.8 6.5 13.9 8.5 6.6 9.7 1.0 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex MxiH PF09392.5 CDI87487.1 - 1 9.9 6.3 2.6 8.6 4.1 1.9 1 1 0 1 1 1 0 Type III secretion needle MxiH like IncA PF04156.9 CDI87487.1 - 2.5 7.6 11.0 1.2 8.6 4.5 2.2 2 0 0 2 2 2 0 IncA protein MFS_1 PF07690.11 CDI87488.1 - 6.4e-17 61.3 28.6 3.3e-11 42.5 9.6 2.7 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.15 CDI87488.1 - 6.4e-09 34.3 1.3 3.7e-06 25.3 0.1 3.1 2 1 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family Sugar_tr PF00083.19 CDI87488.1 - 5.2e-07 28.6 2.5 3.9e-05 22.4 0.0 2.9 3 0 0 3 3 3 2 Sugar (and other) transporter Ribosomal_S4 PF00163.14 CDI87489.1 - 1.2e-24 86.5 3.8 2e-24 85.7 2.7 1.4 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.20 CDI87489.1 - 3.8e-13 48.6 2.6 4.3e-13 48.4 0.3 2.2 2 0 0 2 2 2 1 S4 domain DOT1 PF08123.8 CDI87490.1 - 4e-05 23.0 0.0 7.4e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 Histone methylation protein DOT1 EGF_2 PF07974.8 CDI87491.1 - 2.4e-14 53.1 191.2 0.00018 21.5 8.6 10.6 10 0 0 10 10 10 8 EGF-like domain hEGF PF12661.2 CDI87491.1 - 0.00012 21.9 11.9 0.00024 20.9 2.0 10.7 9 0 0 9 9 9 4 Human growth factor-like EGF DUF4366 PF14283.1 CDI87491.1 - 0.011 15.1 0.0 0.023 14.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) ETRAMP PF09716.5 CDI87491.1 - 0.048 13.6 0.1 0.13 12.1 0.0 1.8 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) MIT PF04212.13 CDI87491.1 - 0.16 11.9 0.0 0.29 11.0 0.0 1.4 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain Ank_2 PF12796.2 CDI87494.1 - 2.1e-59 197.8 7.6 3.2e-19 69.0 0.1 6.8 3 2 3 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.25 CDI87494.1 - 8e-38 126.4 7.7 0.0013 18.4 0.0 10.9 11 0 0 11 11 11 8 Ankyrin repeat Ank_5 PF13857.1 CDI87494.1 - 6.7e-35 118.3 2.1 2.9e-06 27.3 0.1 8.0 5 1 3 8 8 8 7 Ankyrin repeats (many copies) Ank_4 PF13637.1 CDI87494.1 - 5.1e-33 112.8 0.7 7e-06 26.4 0.0 7.4 5 3 3 8 8 8 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 CDI87494.1 - 2e-28 95.5 0.1 0.027 14.7 0.0 10.0 10 0 0 10 10 10 7 Ankyrin repeat Trep_dent_lipo PF09710.5 CDI87494.1 - 0.031 12.9 1.2 0.05 12.2 0.8 1.2 1 0 0 1 1 1 0 Treponema clustered lipoprotein (Trep_dent_lipo) TFIIA PF03153.8 CDI87494.1 - 0.3 10.9 21.4 0.26 11.1 3.8 2.5 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Thioredoxin_8 PF13905.1 CDI87495.1 - 0.0062 16.6 0.0 0.052 13.6 0.0 2.1 2 0 0 2 2 2 1 Thioredoxin-like Thioredoxin PF00085.15 CDI87495.1 - 0.015 15.0 0.0 0.028 14.0 0.0 1.5 2 0 0 2 2 2 0 Thioredoxin Thioredoxin_2 PF13098.1 CDI87495.1 - 0.053 13.7 0.0 0.079 13.1 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin-like domain CAAD PF14159.1 CDI87496.1 - 0.69 9.5 0.0 0.69 9.5 0.0 2.4 3 0 0 3 3 3 0 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase LMBR1 PF04791.11 CDI87496.1 - 1.8 7.0 9.9 2.7 6.4 6.8 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein DDHD PF02862.12 CDI87497.1 - 9.5 5.9 30.7 11 5.6 21.3 1.1 1 0 0 1 1 1 0 DDHD domain tRNA_anti-codon PF01336.20 CDI87499.1 - 1.2e-05 25.0 0.0 2.2e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Activator_LAG-3 PF11498.3 CDI87499.1 - 5.1e-05 22.2 34.1 0.00054 18.8 11.6 2.6 2 0 0 2 2 2 2 Transcriptional activator LAG-3 Sporozoite_P67 PF05642.6 CDI87499.1 - 0.0018 16.2 4.6 0.0048 14.8 3.0 1.9 1 1 0 1 1 1 1 Sporozoite P67 surface antigen SseC PF04888.7 CDI87499.1 - 0.0044 16.3 11.3 0.0044 16.3 7.9 5.3 3 2 1 4 4 1 1 Secretion system effector C (SseC) like family Spt20 PF12090.3 CDI87499.1 - 0.0061 15.9 11.1 0.22 10.8 0.4 2.3 2 0 0 2 2 2 2 Spt20 family RAB3GAP2_N PF14655.1 CDI87499.1 - 0.051 12.5 15.8 0.12 11.3 1.6 2.4 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Glucan_synthase PF02364.10 CDI87499.1 - 0.078 10.8 0.9 0.15 9.8 0.0 1.7 2 0 0 2 2 2 0 1,3-beta-glucan synthase component zf-DHHC PF01529.15 CDI87499.1 - 0.096 12.0 1.2 3.7 6.9 0.1 2.2 2 0 0 2 2 2 0 DHHC palmitoyltransferase DUF1360 PF07098.6 CDI87499.1 - 0.12 12.1 6.3 0.95 9.2 1.1 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1360) Ycf1 PF05758.7 CDI87499.1 - 0.28 8.8 3.0 1.2 6.7 0.1 2.0 2 0 0 2 2 2 0 Ycf1 SR-25 PF10500.4 CDI87499.1 - 0.33 10.3 23.4 0.23 10.9 5.7 3.3 3 0 0 3 3 3 0 Nuclear RNA-splicing-associated protein Mus7 PF09462.5 CDI87499.1 - 0.47 9.2 12.1 1.3 7.7 1.5 2.1 2 0 0 2 2 2 0 Mus7/MMS22 family FimP PF09766.4 CDI87499.1 - 1 8.3 22.3 0.54 9.2 5.5 2.1 2 0 0 2 2 2 0 Fms-interacting protein DUF4207 PF13904.1 CDI87499.1 - 1.1 8.5 32.1 0.17 11.2 2.7 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4207) SGT1 PF07093.6 CDI87499.1 - 1.2 7.4 10.3 1.3 7.3 0.2 2.3 2 0 0 2 2 2 0 SGT1 protein ATAD4 PF15321.1 CDI87499.1 - 1.6 9.7 12.8 7.4 7.6 0.9 3.4 3 0 0 3 3 3 0 ATPase family AAA domain containing 4 LIM_bind PF01803.11 CDI87499.1 - 3.4 6.7 14.2 2 7.4 3.5 2.4 2 0 0 2 2 2 0 LIM-domain binding protein Rsc14 PF08586.5 CDI87499.1 - 3.5 8.1 7.2 6.2 7.3 0.1 2.3 2 0 0 2 2 2 0 RSC complex, Rsc14/Ldb7 subunit PH_4 PF15404.1 CDI87499.1 - 4 6.9 11.0 2 7.8 0.5 2.5 2 0 0 2 2 2 0 Pleckstrin homology domain Rpp20 PF12328.3 CDI87499.1 - 4.1 7.0 13.6 2.8 7.6 1.2 2.4 2 0 0 2 2 2 0 Rpp20 subunit of nuclear RNase MRP and P DUF4611 PF15387.1 CDI87499.1 - 8.6 6.5 11.0 0.5 10.5 0.5 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) DUF3115 PF11312.3 CDI87499.1 - 8.8 5.0 11.7 2.1 7.0 4.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3115) Draxin PF15550.1 CDI87500.1 - 0.38 10.3 9.2 0.44 10.1 6.4 1.2 1 0 0 1 1 1 0 Draxin NST1 PF13945.1 CDI87500.1 - 0.51 10.3 15.5 0.63 10.0 10.7 1.3 1 0 0 1 1 1 0 Salt tolerance down-regulator DUF755 PF05501.6 CDI87500.1 - 0.8 9.7 20.0 1 9.4 13.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF755) Bud13 PF09736.4 CDI87500.1 - 0.84 9.8 9.4 0.91 9.7 6.5 1.2 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex LCD1 PF09798.4 CDI87500.1 - 1.3 6.9 5.1 1.2 7.0 3.5 1.1 1 0 0 1 1 1 0 DNA damage checkpoint protein FAM60A PF15396.1 CDI87500.1 - 1.3 8.6 9.3 1.4 8.6 6.4 1.2 1 0 0 1 1 1 0 Protein Family FAM60A THRAP3_BCLAF1 PF15440.1 CDI87500.1 - 1.3 7.5 14.4 1.5 7.4 10.0 1.0 1 0 0 1 1 1 0 THRAP3/BCLAF1 family DUF2217 PF10265.4 CDI87500.1 - 3.1 6.4 13.7 3.3 6.3 9.5 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) DDRGK PF09756.4 CDI87500.1 - 3.2 7.1 11.2 3.5 6.9 7.8 1.1 1 0 0 1 1 1 0 DDRGK domain SOBP PF15279.1 CDI87500.1 - 5 7.4 16.9 5.4 7.2 11.7 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein Hid1 PF12722.2 CDI87500.1 - 5.5 4.5 14.6 5.6 4.5 10.1 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Plasmodium_Vir PF05795.6 CDI87500.1 - 6.2 5.9 5.6 6.5 5.8 3.9 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein SLD3 PF08639.5 CDI87500.1 - 6.5 5.2 16.9 6.5 5.2 11.7 1.1 1 0 0 1 1 1 0 DNA replication regulator SLD3 Peptidase_S64 PF08192.6 CDI87500.1 - 7.3 4.7 15.3 7.9 4.6 10.6 1.0 1 0 0 1 1 1 0 Peptidase family S64 RED_N PF07808.8 CDI87500.1 - 7.5 5.6 11.8 9.5 5.3 8.2 1.3 1 0 0 1 1 1 0 RED-like protein N-terminal region GPCR_chapero_1 PF11904.3 CDI87500.1 - 7.7 5.5 10.1 8.5 5.4 7.0 1.1 1 0 0 1 1 1 0 GPCR-chaperone FAM176 PF14851.1 CDI87500.1 - 8.3 6.0 6.6 12 5.6 4.6 1.2 1 0 0 1 1 1 0 FAM176 family Band_3_cyto PF07565.8 CDI87500.1 - 8.8 5.7 9.3 8.6 5.7 6.5 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain IncA PF04156.9 CDI87501.1 - 6e-11 42.2 24.7 6e-11 42.2 17.1 6.8 2 2 1 4 4 4 1 IncA protein YjgP_YjgQ PF03739.9 CDI87501.1 - 0.0015 17.3 1.4 0.0015 17.3 1.0 3.8 2 2 1 3 3 3 1 Predicted permease YjgP/YjgQ family CD20 PF04103.10 CDI87501.1 - 0.0053 16.6 3.0 0.0053 16.6 2.1 5.0 1 1 1 2 2 2 1 CD20-like family FA_desaturase PF00487.19 CDI87501.1 - 7.6 5.8 9.5 2.5 7.4 1.2 2.4 1 1 1 2 2 2 0 Fatty acid desaturase Gag_spuma PF03276.9 CDI87502.1 - 1.1 7.5 34.1 1.2 7.4 23.7 1.2 1 0 0 1 1 1 0 Spumavirus gag protein Paf1 PF03985.8 CDI87502.1 - 1.8 7.2 22.9 1.9 7.1 15.9 1.2 1 0 0 1 1 1 0 Paf1 Band_3_cyto PF07565.8 CDI87502.1 - 2.6 7.5 24.1 3.1 7.2 16.7 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain CDC45 PF02724.9 CDI87502.1 - 3.2 5.6 21.3 3.4 5.5 14.8 1.1 1 0 0 1 1 1 0 CDC45-like protein Plasmodium_Vir PF05795.6 CDI87502.1 - 3.3 6.8 12.1 3.8 6.6 8.4 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Peptidase_S30 PF01577.11 CDI87502.1 - 3.6 6.9 26.3 4.1 6.7 18.2 1.2 1 0 0 1 1 1 0 Potyvirus P1 protease Dynamin_N PF00350.18 CDI87502.1 - 4.4 7.0 15.4 6.7 6.5 10.7 1.3 1 0 0 1 1 1 0 Dynamin family Bul1_N PF04425.7 CDI87502.1 - 4.6 5.6 16.3 4.7 5.6 11.3 1.1 1 0 0 1 1 1 0 Bul1 N terminus Glyco_transf_6 PF03414.8 CDI87502.1 - 5.4 5.3 13.4 6.2 5.1 9.3 1.1 1 0 0 1 1 1 0 Glycosyltransferase family 6 Raftlin PF15250.1 CDI87502.1 - 5.7 5.3 21.5 6 5.2 14.9 1.2 1 0 0 1 1 1 0 Raftlin DUF4652 PF15525.1 CDI87502.1 - 6.2 6.2 21.0 7.2 5.9 14.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4652) Apt1 PF10351.4 CDI87502.1 - 6.2 5.5 16.7 6.7 5.4 11.6 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Folate_carrier PF01770.13 CDI87502.1 - 9.3 4.6 16.0 11 4.4 11.1 1.1 1 0 0 1 1 1 0 Reduced folate carrier Dynein_light PF01221.13 CDI87503.1 - 3.1e-07 30.3 0.0 4e-07 29.9 0.0 1.2 1 0 0 1 1 1 1 Dynein light chain type 1 PAT1 PF09770.4 CDI87505.1 - 0.064 11.4 33.3 0.072 11.3 23.1 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Mpp10 PF04006.7 CDI87507.1 - 0.3 9.3 64.7 0.35 9.1 44.9 1.1 1 0 0 1 1 1 0 Mpp10 protein CENP-T PF15511.1 CDI87507.1 - 5.3 6.1 40.8 6.5 5.8 28.3 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T DUF740 PF05340.7 CDI87508.1 - 0.081 11.2 7.4 0.1 10.9 5.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF740) Ycf1 PF05758.7 CDI87508.1 - 0.34 8.5 12.1 0.39 8.3 8.4 1.1 1 0 0 1 1 1 0 Ycf1 TLP-20 PF06088.6 CDI87508.1 - 2 8.0 14.8 3.4 7.3 0.0 2.4 2 1 0 2 2 2 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) RR_TM4-6 PF06459.7 CDI87508.1 - 2.2 8.0 17.8 2.9 7.7 12.4 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Spore_coat_CotO PF14153.1 CDI87508.1 - 3.1 7.2 18.1 0.77 9.1 10.6 1.5 2 0 0 2 2 2 0 Spore coat protein CotO APG6 PF04111.7 CDI87508.1 - 8.6 5.2 18.5 11 4.8 12.8 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF3367 PF11847.3 CDI87508.1 - 8.6 4.1 7.8 10 3.9 5.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3367) Presenilin PF01080.12 CDI87509.1 - 0.00012 20.9 8.5 0.00017 20.5 5.9 1.2 1 0 0 1 1 1 1 Presenilin Ribosomal_60s PF00428.14 CDI87509.1 - 0.00088 19.6 17.8 0.0074 16.6 2.9 2.6 2 0 0 2 2 2 2 60s Acidic ribosomal protein DUF3801 PF12687.2 CDI87509.1 - 0.028 14.0 11.3 0.032 13.8 7.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3801) PBP1_TM PF14812.1 CDI87509.1 - 0.17 12.1 1.3 0.62 10.4 0.0 2.1 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CD20 PF04103.10 CDI87509.1 - 0.23 11.4 6.5 20 5.1 4.5 2.4 1 1 0 1 1 1 0 CD20-like family SprA-related PF12118.3 CDI87509.1 - 0.48 9.7 39.3 0.64 9.2 27.3 1.1 1 0 0 1 1 1 0 SprA-related family DUF3366 PF11846.3 CDI87509.1 - 0.69 9.7 14.0 1.1 9.0 9.7 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF3366) 7tm_1 PF00001.16 CDI87509.1 - 1.5 7.9 6.8 11 5.1 4.7 2.2 1 1 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) DUF4048 PF13257.1 CDI87509.1 - 1.9 8.0 22.4 2.6 7.6 15.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4048) Med15 PF09606.5 CDI87509.1 - 2.6 6.1 38.9 3.4 5.7 27.0 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Parvo_coat PF00740.13 CDI87509.1 - 3.3 6.5 23.5 4.1 6.2 16.3 1.0 1 0 0 1 1 1 0 Parvovirus coat protein VP2 DUF966 PF06136.8 CDI87509.1 - 5.4 6.3 21.1 7 5.9 14.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) SseC PF04888.7 CDI87511.1 - 0.00066 19.1 16.6 0.00066 19.1 11.5 4.2 3 1 0 3 3 1 1 Secretion system effector C (SseC) like family BAF1_ABF1 PF04684.8 CDI87511.1 - 0.0016 17.3 21.2 0.0016 17.3 14.7 4.2 3 1 1 4 4 2 2 BAF1 / ABF1 chromatin reorganising factor NTP_transf_3 PF12804.2 CDI87511.1 - 0.026 14.5 2.2 0.027 14.5 0.6 1.7 2 0 0 2 2 2 0 MobA-like NTP transferase domain DUF1510 PF07423.6 CDI87511.1 - 0.027 13.8 74.7 0.17 11.2 19.8 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1510) PGA2 PF07543.7 CDI87511.1 - 0.041 13.6 0.3 0.041 13.6 0.2 4.4 3 1 1 4 4 3 0 Protein trafficking PGA2 Pox_Ag35 PF03286.9 CDI87511.1 - 0.055 12.9 53.4 0.026 14.0 6.2 3.3 3 0 0 3 3 3 0 Pox virus Ag35 surface protein DUF2052 PF09747.4 CDI87511.1 - 0.072 13.0 69.7 1 9.2 12.5 3.3 3 0 0 3 3 3 0 Coiled-coil domain containing protein (DUF2052) Cwf_Cwc_15 PF04889.7 CDI87511.1 - 0.23 11.1 62.7 0.14 11.8 7.6 3.2 3 0 0 3 3 3 0 Cwf15/Cwc15 cell cycle control protein DUF4045 PF13254.1 CDI87511.1 - 1.3 8.2 60.0 2.9 7.0 8.1 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4045) Na_trans_assoc PF06512.8 CDI87511.1 - 1.8 8.4 44.4 0.85 9.5 4.4 3.2 3 0 0 3 3 3 0 Sodium ion transport-associated Spore_coat_CotO PF14153.1 CDI87511.1 - 2 7.8 83.3 1 8.7 21.4 3.2 3 0 0 3 3 3 0 Spore coat protein CotO DUF4246 PF14033.1 CDI87511.1 - 5.3 5.5 43.0 1.1 7.7 3.6 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF4246) MMR1 PF08505.5 CDI87511.1 - 8.5 6.3 64.3 0.19 11.7 9.2 3.1 3 0 0 3 3 3 0 Mitochondrial Myo2 receptor-related protein DDRGK PF09756.4 CDI87511.1 - 9.5 5.5 82.2 0.053 12.9 7.8 3.2 3 0 0 3 3 3 0 DDRGK domain Trypan_PARP PF05887.6 CDI87512.1 - 0.36 10.6 24.8 0.028 14.2 2.9 2.6 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) zf-DHHC PF01529.15 CDI87514.1 - 2.1 7.7 10.2 1.4 8.2 0.2 2.2 2 0 0 2 2 2 0 DHHC palmitoyltransferase FimP PF09766.4 CDI87514.1 - 4.3 6.3 36.0 1.5 7.7 8.3 2.2 2 0 0 2 2 2 0 Fms-interacting protein DUF3314 PF11771.3 CDI87515.1 - 0.0026 17.5 2.5 0.0037 17.0 1.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3314) Glu_synthase PF01645.12 CDI87515.1 - 6.2 5.6 9.0 0.47 9.3 2.5 1.7 1 1 1 2 2 2 0 Conserved region in glutamate synthase GTP1_OBG PF01018.17 CDI87516.1 - 4.3e-21 75.1 5.9 1.6e-12 47.3 1.9 2.4 2 0 0 2 2 2 2 GTP1/OBG GTP_EFTU PF00009.22 CDI87516.1 - 2.6e-06 26.9 0.0 7e-05 22.3 0.0 2.6 3 0 0 3 3 3 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 CDI87516.1 - 8.6e-06 25.6 0.0 6.8e-05 22.8 0.0 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.16 CDI87516.1 - 0.0011 18.1 0.0 0.0025 17.0 0.0 1.5 1 0 0 1 1 1 1 ADP-ribosylation factor family ATP_bind_1 PF03029.12 CDI87516.1 - 0.0015 18.0 0.0 0.0041 16.6 0.0 1.7 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein Gtr1_RagA PF04670.7 CDI87516.1 - 0.25 10.4 0.0 0.44 9.6 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region IMS PF00817.15 CDI87518.1 - 2.6e-19 69.5 1.1 7.8e-09 35.4 0.0 3.3 2 1 1 3 3 3 2 impB/mucB/samB family IMS_C PF11799.3 CDI87518.1 - 1.7e-13 50.6 0.2 4.7e-13 49.1 0.1 1.7 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.3 CDI87518.1 - 0.00023 20.9 0.0 0.0006 19.7 0.0 1.7 1 0 0 1 1 1 1 IMS family HHH motif Cdd1 PF11731.3 CDI87518.1 - 0.067 13.1 0.0 0.15 11.9 0.0 1.6 1 0 0 1 1 1 0 Pathogenicity locus Pneumo_att_G PF05539.6 CDI87518.1 - 3.1 7.0 8.4 7.7 5.7 5.8 1.6 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G Folate_rec PF03024.9 CDI87519.1 - 1.3e-10 41.1 5.9 1.9e-10 40.6 4.1 1.3 1 0 0 1 1 1 1 Folate receptor family MORN PF02493.15 CDI87520.1 - 1.5e-11 43.3 11.0 0.00036 20.0 0.0 5.4 5 0 0 5 5 5 4 MORN repeat AP2 PF00847.15 CDI87520.1 - 0.057 13.5 0.3 0.17 12.0 0.2 1.7 1 0 0 1 1 1 0 AP2 domain BTK PF00779.14 CDI87522.1 - 0.032 13.8 5.5 2.5 7.7 0.3 2.5 2 0 0 2 2 2 0 BTK motif FAM60A PF15396.1 CDI87522.1 - 6.7 6.4 9.4 15 5.2 6.5 1.6 1 0 0 1 1 1 0 Protein Family FAM60A Activator_LAG-3 PF11498.3 CDI87525.1 - 0.00016 20.5 54.1 0.019 13.7 29.9 2.6 2 0 0 2 2 2 2 Transcriptional activator LAG-3 Ribosomal_60s PF00428.14 CDI87525.1 - 0.00047 20.5 5.2 0.00047 20.5 3.6 7.5 2 1 3 5 5 5 1 60s Acidic ribosomal protein AAA_23 PF13476.1 CDI87525.1 - 1.4 9.1 27.7 0.11 12.7 2.5 2.4 2 0 0 2 2 2 0 AAA domain Spt20 PF12090.3 CDI87527.1 - 0.71 9.1 15.2 3.6 6.9 1.1 3.3 3 0 0 3 3 3 0 Spt20 family UIM PF02809.15 CDI87529.1 - 0.0025 17.2 0.8 0.0069 15.8 0.5 1.8 1 0 0 1 1 1 1 Ubiquitin interaction motif Macoilin PF09726.4 CDI87529.1 - 0.13 10.4 6.0 0.13 10.4 4.1 1.1 1 0 0 1 1 1 0 Transmembrane protein MDFI PF15316.1 CDI87529.1 - 0.33 10.9 5.8 0.45 10.4 4.0 1.3 1 0 0 1 1 1 0 MyoD family inhibitor TFIIA PF03153.8 CDI87529.1 - 0.5 10.2 16.5 0.5 10.2 11.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF2217 PF10265.4 CDI87529.1 - 10 4.7 12.9 15 4.2 8.9 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) FAM60A PF15396.1 CDI87531.1 - 1.4 8.6 25.5 1.6 8.4 17.6 1.1 1 0 0 1 1 1 0 Protein Family FAM60A Ycf1 PF05758.7 CDI87531.1 - 1.6 6.3 27.8 1.8 6.1 19.3 1.0 1 0 0 1 1 1 0 Ycf1 CDC45 PF02724.9 CDI87531.1 - 1.8 6.4 29.1 2.2 6.2 20.2 1.0 1 0 0 1 1 1 0 CDC45-like protein HCO3_cotransp PF00955.16 CDI87531.1 - 2.1 6.9 9.3 2.4 6.7 6.5 1.1 1 0 0 1 1 1 0 HCO3- transporter family PAT1 PF09770.4 CDI87531.1 - 2.2 6.3 64.4 2.4 6.2 44.6 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 RR_TM4-6 PF06459.7 CDI87531.1 - 2.9 7.7 24.9 4.1 7.2 17.2 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Hid1 PF12722.2 CDI87531.1 - 3 5.4 30.5 3.4 5.2 21.2 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF4045 PF13254.1 CDI87531.1 - 3.6 6.7 23.9 3.7 6.7 16.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Spore_coat_CotO PF14153.1 CDI87531.1 - 6 6.2 36.0 9 5.6 25.0 1.3 1 0 0 1 1 1 0 Spore coat protein CotO HGTP_anticodon2 PF12745.2 CDI87531.1 - 7.5 5.6 25.5 10 5.1 17.7 1.2 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs SAGA-Tad1 PF12767.2 CDI87531.1 - 8.1 6.0 32.4 10 5.6 22.5 1.2 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit Raftlin PF15250.1 CDI87531.1 - 8.4 4.7 29.0 10 4.5 20.1 1.1 1 0 0 1 1 1 0 Raftlin Utp14 PF04615.8 CDI87532.1 - 0.47 8.5 26.8 0.59 8.2 18.6 1.0 1 0 0 1 1 1 0 Utp14 protein CDC27 PF09507.5 CDI87532.1 - 0.53 9.4 27.5 0.95 8.6 19.1 1.3 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 DUF2217 PF10265.4 CDI87532.1 - 5 5.7 10.9 7.2 5.2 7.5 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) LMBR1 PF04791.11 CDI87533.1 - 0.14 10.7 0.0 0.14 10.7 0.0 6.2 4 1 0 6 6 6 0 LMBR1-like membrane protein IncA PF04156.9 CDI87534.1 - 0.00075 19.1 18.9 0.00091 18.8 13.1 1.1 1 0 0 1 1 1 1 IncA protein Peptidase_S49_N PF08496.5 CDI87534.1 - 0.031 14.0 10.8 0.038 13.7 7.5 1.0 1 0 0 1 1 1 0 Peptidase family S49 N-terminal GDE_N PF12439.3 CDI87534.1 - 0.062 12.5 7.9 0.074 12.2 5.5 1.1 1 0 0 1 1 1 0 Glycogen debranching enzyme N terminal DUF2126 PF09899.4 CDI87534.1 - 0.082 10.9 9.1 0.09 10.7 6.3 1.0 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) Nucleoside_tran PF01733.13 CDI87534.1 - 0.098 11.7 2.2 0.11 11.6 1.5 1.0 1 0 0 1 1 1 0 Nucleoside transporter Packaging_FI PF14000.1 CDI87534.1 - 0.1 12.8 6.1 0.13 12.4 4.3 1.2 1 0 0 1 1 1 0 DNA packaging protein FI Shadoo PF14999.1 CDI87534.1 - 0.11 12.3 4.0 0.14 12.0 2.8 1.2 1 0 0 1 1 1 0 Shadow of prion protein, neuroprotective DUF4446 PF14584.1 CDI87534.1 - 0.12 12.2 5.4 0.13 12.0 3.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) OATP PF03137.15 CDI87534.1 - 0.17 9.9 7.5 0.18 9.7 5.2 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Spc7_N PF15402.1 CDI87534.1 - 0.17 9.8 15.0 0.19 9.7 10.4 1.0 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 Folate_carrier PF01770.13 CDI87534.1 - 0.21 10.0 5.6 0.23 9.9 3.9 1.1 1 0 0 1 1 1 0 Reduced folate carrier DUF2232 PF09991.4 CDI87534.1 - 0.24 10.3 6.4 0.29 10.0 4.4 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) BTV_NS2 PF04514.7 CDI87534.1 - 0.24 10.2 5.7 0.25 10.1 3.9 1.0 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Ald_Xan_dh_C2 PF02738.13 CDI87534.1 - 0.31 9.2 7.6 0.36 9.1 5.2 1.0 1 0 0 1 1 1 0 Molybdopterin-binding domain of aldehyde dehydrogenase PAT1 PF09770.4 CDI87534.1 - 0.44 8.7 40.9 0.47 8.6 28.3 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Ctr PF04145.10 CDI87534.1 - 0.45 10.5 6.6 0.59 10.1 4.5 1.1 1 0 0 1 1 1 0 Ctr copper transporter family FAM176 PF14851.1 CDI87534.1 - 0.5 10.0 3.9 0.63 9.7 2.7 1.1 1 0 0 1 1 1 0 FAM176 family CD20 PF04103.10 CDI87534.1 - 0.52 10.2 6.1 1.5 8.7 4.2 1.8 1 1 0 1 1 1 0 CD20-like family HemX PF04375.9 CDI87534.1 - 0.53 8.8 30.6 0.61 8.6 21.2 1.0 1 0 0 1 1 1 0 HemX CLP_protease PF00574.18 CDI87534.1 - 0.54 9.8 7.8 0.61 9.7 5.4 1.1 1 0 0 1 1 1 0 Clp protease CPSF100_C PF13299.1 CDI87534.1 - 0.57 10.3 9.0 0.64 10.1 6.2 1.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Pilus_CpaD PF09476.5 CDI87534.1 - 0.58 9.5 15.2 0.73 9.2 10.5 1.2 1 0 0 1 1 1 0 Pilus biogenesis CpaD protein (pilus_cpaD) R_equi_Vir PF05526.6 CDI87534.1 - 0.59 9.7 9.1 0.81 9.3 6.3 1.2 1 0 0 1 1 1 0 Rhodococcus equi virulence-associated protein GAGA_bind PF06217.7 CDI87534.1 - 0.6 10.0 10.6 0.6 10.0 7.4 1.0 1 0 0 1 1 1 0 GAGA binding protein-like family DUF4557 PF15101.1 CDI87534.1 - 0.68 9.7 20.7 0.91 9.3 14.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) DUF1764 PF08576.5 CDI87534.1 - 0.74 10.6 9.6 0.93 10.3 6.6 1.3 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) Draxin PF15550.1 CDI87534.1 - 0.75 9.3 9.6 0.93 9.0 6.7 1.0 1 0 0 1 1 1 0 Draxin Dala_Dala_lig_N PF01820.16 CDI87534.1 - 0.89 9.8 4.6 1.1 9.6 3.2 1.3 1 0 0 1 1 1 0 D-ala D-ala ligase N-terminus DUF2048 PF09752.4 CDI87534.1 - 1.1 8.0 8.2 1.4 7.7 5.7 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2048) Serinc PF03348.10 CDI87534.1 - 1.3 7.6 10.7 1.4 7.5 7.4 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) Band_3_cyto PF07565.8 CDI87534.1 - 1.3 8.4 12.2 1.5 8.2 8.5 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Peptidase_S15 PF02129.13 CDI87534.1 - 1.4 8.2 13.6 1.8 7.9 9.4 1.0 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Suf PF05843.9 CDI87534.1 - 1.4 8.5 18.4 1.7 8.2 12.8 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) RR_TM4-6 PF06459.7 CDI87534.1 - 1.8 8.4 12.2 2 8.2 8.4 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 APG6 PF04111.7 CDI87534.1 - 1.9 7.4 16.2 1.9 7.4 11.2 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 FAM60A PF15396.1 CDI87534.1 - 2.1 8.0 8.3 2.1 8.0 5.8 1.1 1 0 0 1 1 1 0 Protein Family FAM60A DUF2930 PF11152.3 CDI87534.1 - 2.2 7.3 8.9 2.2 7.4 5.7 1.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2930) PBP1_TM PF14812.1 CDI87534.1 - 2.3 8.6 5.5 3 8.1 3.8 1.1 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Peptidase_U57 PF05582.7 CDI87534.1 - 2.3 7.0 8.8 2.5 6.9 6.1 1.0 1 0 0 1 1 1 0 YabG peptidase U57 FLO_LFY PF01698.11 CDI87534.1 - 2.4 6.9 12.1 2.8 6.6 8.4 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein eIF-3_zeta PF05091.7 CDI87534.1 - 2.6 6.5 14.8 2.6 6.5 10.2 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF2407 PF10302.4 CDI87534.1 - 2.8 8.2 8.6 7.3 6.8 5.9 1.7 1 1 0 1 1 1 0 DUF2407 ubiquitin-like domain FliP PF00813.15 CDI87534.1 - 2.8 7.6 8.5 3.5 7.2 5.9 1.3 1 0 0 1 1 1 0 FliP family Sec62 PF03839.11 CDI87534.1 - 3 7.2 5.9 3.2 7.0 4.1 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 Baculo_PP31 PF05311.6 CDI87534.1 - 3.2 6.9 10.4 3.5 6.8 7.2 1.1 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) Med19 PF10278.4 CDI87534.1 - 3.6 7.2 8.9 4.3 6.9 6.2 1.1 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 DUF342 PF03961.8 CDI87534.1 - 3.9 5.7 7.8 4.1 5.7 5.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) PMSI1 PF15322.1 CDI87534.1 - 4.1 6.4 12.7 5 6.1 8.8 1.0 1 0 0 1 1 1 0 Protein missing in infertile sperm 1, putative MDFI PF15316.1 CDI87534.1 - 4.1 7.3 7.1 6.2 6.7 4.9 1.3 1 0 0 1 1 1 0 MyoD family inhibitor YABBY PF04690.8 CDI87534.1 - 4.2 7.5 9.5 4.9 7.3 6.6 1.1 1 0 0 1 1 1 0 YABBY protein Gag_spuma PF03276.9 CDI87534.1 - 4.2 5.5 24.9 4.6 5.4 17.3 1.1 1 0 0 1 1 1 0 Spumavirus gag protein HlyD_2 PF12700.2 CDI87534.1 - 4.5 6.3 12.1 4.4 6.3 8.4 1.1 1 0 0 1 1 1 0 HlyD family secretion protein SID-1_RNA_chan PF13965.1 CDI87534.1 - 4.8 5.2 7.0 5.1 5.1 4.9 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Spore_coat_CotO PF14153.1 CDI87534.1 - 5 6.5 19.0 5.5 6.3 13.2 1.1 1 0 0 1 1 1 0 Spore coat protein CotO Neur_chan_memb PF02932.11 CDI87534.1 - 5.1 6.9 7.5 5.7 6.7 5.2 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Med15 PF09606.5 CDI87534.1 - 5.1 5.1 52.4 7.1 4.6 36.3 1.3 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DDHD PF02862.12 CDI87534.1 - 5.4 6.7 11.5 6 6.5 8.0 1.1 1 0 0 1 1 1 0 DDHD domain FHIPEP PF00771.15 CDI87534.1 - 5.5 5.2 10.3 6.2 5.0 7.1 1.1 1 0 0 1 1 1 0 FHIPEP family Activator_LAG-3 PF11498.3 CDI87534.1 - 5.9 5.5 53.2 7.2 5.2 36.8 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 DUF940 PF06082.6 CDI87534.1 - 6.3 5.2 12.3 7 5.0 8.5 1.0 1 0 0 1 1 1 0 Bacterial putative lipoprotein (DUF940) AAA_23 PF13476.1 CDI87534.1 - 6.8 6.9 17.6 7.5 6.8 12.2 1.1 1 0 0 1 1 1 0 AAA domain Gastrin PF00918.12 CDI87534.1 - 6.9 7.5 24.1 8.7 7.1 16.7 1.1 1 0 0 1 1 1 0 Gastrin/cholecystokinin family Calc_CGRP_IAPP PF00214.14 CDI87534.1 - 8.5 6.4 11.1 12 5.9 7.7 1.3 1 0 0 1 1 1 0 Calcitonin / CGRP / IAPP family Herpes_DNAp_acc PF04929.7 CDI87534.1 - 9.5 5.0 11.6 9.9 5.0 8.0 1.0 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Presenilin PF01080.12 CDI87534.1 - 9.5 4.9 11.7 11 4.6 8.1 1.0 1 0 0 1 1 1 0 Presenilin Glyco_transf_15 PF01793.11 CDI87534.1 - 9.7 5.0 11.5 12 4.7 7.9 1.1 1 0 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase Exonuc_VII_L PF02601.10 CDI87534.1 - 10 5.2 17.0 12 4.9 11.8 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit TFIIA PF03153.8 CDI87535.1 - 0.49 10.2 11.8 0.63 9.8 8.2 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Peptidase_C14 PF00656.17 CDI87535.1 - 1.7 8.2 3.9 2.3 7.8 2.7 1.3 1 0 0 1 1 1 0 Caspase domain DNA_pol_viral_N PF00242.12 CDI87535.1 - 8.6 5.2 6.8 11 4.9 4.7 1.0 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain Macoilin PF09726.4 CDI87535.1 - 9.1 4.4 8.4 11 4.1 5.8 1.1 1 0 0 1 1 1 0 Transmembrane protein TEA PF01285.13 CDI87536.1 - 2.6 7.0 5.4 3.7 6.5 3.8 1.2 1 0 0 1 1 1 0 TEA/ATTS domain family Stk19 PF10494.4 CDI87538.1 - 0.00087 18.7 15.6 0.0025 17.2 10.9 1.6 1 1 0 1 1 1 1 Serine-threonine protein kinase 19 Pkinase PF00069.20 CDI87539.1 - 1.4e-18 67.0 0.0 1.4e-18 67.0 0.0 3.3 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDI87539.1 - 1.3e-10 40.7 0.2 1.3e-10 40.7 0.2 2.5 2 0 0 2 2 2 1 Protein tyrosine kinase N6_N4_Mtase PF01555.13 CDI87539.1 - 0.81 9.1 7.5 27 4.1 5.2 2.5 1 1 0 1 1 1 0 DNA methylase DUF4407 PF14362.1 CDI87540.1 - 0.078 11.9 13.1 0.079 11.9 9.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) RR_TM4-6 PF06459.7 CDI87540.1 - 0.36 10.6 13.6 0.37 10.6 9.4 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Peptidase_S15 PF02129.13 CDI87540.1 - 0.5 9.7 8.7 0.5 9.7 6.0 1.1 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Asp-B-Hydro_N PF05279.6 CDI87540.1 - 0.68 9.7 8.6 0.74 9.6 6.0 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Band_3_cyto PF07565.8 CDI87540.1 - 0.81 9.1 12.5 0.87 9.0 8.6 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Pal1 PF08316.6 CDI87540.1 - 0.9 9.9 5.6 1 9.7 3.9 1.1 1 0 0 1 1 1 0 Pal1 cell morphology protein BORG_CEP PF14957.1 CDI87540.1 - 1 10.3 11.4 1.1 10.1 7.9 1.1 1 0 0 1 1 1 0 Cdc42 effector Tim54 PF11711.3 CDI87540.1 - 1.1 7.7 9.2 1.3 7.5 6.4 1.0 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 SprA-related PF12118.3 CDI87540.1 - 1.5 8.0 34.8 1.7 7.9 24.1 1.1 1 0 0 1 1 1 0 SprA-related family DUF4557 PF15101.1 CDI87540.1 - 1.8 8.3 22.0 2 8.2 15.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) OmpH PF03938.9 CDI87540.1 - 1.8 8.4 34.1 1.7 8.5 23.6 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) FLO_LFY PF01698.11 CDI87540.1 - 2 7.1 11.2 1.9 7.2 7.8 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein AAA_23 PF13476.1 CDI87540.1 - 2.4 8.4 18.7 2.1 8.6 12.9 1.1 1 0 0 1 1 1 0 AAA domain GAGA_bind PF06217.7 CDI87540.1 - 2.5 7.9 13.2 2.6 7.9 9.1 1.0 1 0 0 1 1 1 0 GAGA binding protein-like family AUX_IAA PF02309.11 CDI87540.1 - 2.7 7.7 10.2 2.8 7.6 7.1 1.1 1 0 0 1 1 1 0 AUX/IAA family FAM60A PF15396.1 CDI87540.1 - 2.7 7.7 10.3 2.9 7.5 7.1 1.1 1 0 0 1 1 1 0 Protein Family FAM60A EIIBC-GUT_N PF03612.9 CDI87540.1 - 2.8 7.5 8.0 3.7 7.1 5.6 1.2 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus FNIP_N PF14636.1 CDI87540.1 - 2.9 8.3 17.2 3.6 8.0 11.9 1.1 1 0 0 1 1 1 0 Folliculin-interacting protein N-terminus Peptidase_S49_N PF08496.5 CDI87540.1 - 3.3 7.5 12.9 4 7.2 9.0 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF2126 PF09899.4 CDI87540.1 - 3.4 5.5 9.7 3.6 5.4 6.7 1.0 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) DDHD PF02862.12 CDI87540.1 - 3.5 7.3 13.0 3.7 7.2 9.0 1.1 1 0 0 1 1 1 0 DDHD domain CPSF100_C PF13299.1 CDI87540.1 - 4.4 7.4 11.3 4.9 7.3 7.9 1.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal UPF0560 PF10577.4 CDI87540.1 - 4.4 5.4 24.3 4.9 5.2 16.8 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 V_ATPase_I PF01496.14 CDI87540.1 - 5.3 4.7 9.5 4.8 4.9 6.6 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Paf1 PF03985.8 CDI87540.1 - 5.4 5.6 19.1 6.4 5.3 13.3 1.0 1 0 0 1 1 1 0 Paf1 DUF3260 PF11658.3 CDI87540.1 - 5.6 4.9 10.8 5.6 4.9 7.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3260) Hid1 PF12722.2 CDI87540.1 - 7 4.1 14.8 6.6 4.2 10.2 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Neur_chan_memb PF02932.11 CDI87540.1 - 7.6 6.3 8.1 7.9 6.2 5.6 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Zip PF02535.17 CDI87540.1 - 8.1 5.3 9.0 8.9 5.2 6.2 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter DUF4512 PF14975.1 CDI87540.1 - 9.7 7.1 7.8 13 6.7 5.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4512) DUF1764 PF08576.5 CDI87540.1 - 9.9 7.0 14.8 15 6.4 10.2 1.3 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) ATG_C PF09333.6 CDI87541.1 - 0.004 17.2 0.0 0.011 15.8 0.0 1.7 1 0 0 1 1 1 1 ATG C terminal domain DUF1162 PF06650.7 CDI87541.1 - 0.11 11.7 0.0 0.51 9.5 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1162) DUF137 PF02006.11 CDI87541.1 - 0.43 9.9 0.0 0.76 9.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF137 Chorein_N PF12624.2 CDI87542.1 - 0.044 13.3 0.0 4.7 6.7 0.0 2.5 2 0 0 2 2 2 0 N-terminal region of Chorein, a TM vesicle-mediated sorter 7TM_GPCR_Sra PF02117.11 CDI87542.1 - 4.1 5.9 0.0 6.8 5.2 0.0 1.2 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Sra Rhomboid PF01694.17 CDI87544.1 - 3.7e-25 88.6 15.0 3.7e-25 88.6 10.4 1.7 2 0 0 2 2 2 1 Rhomboid family DUF1751 PF08551.5 CDI87544.1 - 0.026 14.8 0.0 0.026 14.8 0.0 2.1 3 0 0 3 3 3 0 Eukaryotic integral membrane protein (DUF1751) DER1 PF04511.10 CDI87544.1 - 0.043 13.3 0.6 0.075 12.5 0.4 1.6 1 1 0 1 1 1 0 Der1-like family FixP_N PF14715.1 CDI87544.1 - 0.089 12.1 0.9 0.23 10.8 0.6 1.7 1 0 0 1 1 1 0 N-terminal domain of cytochrome oxidase-cbb3, FixP WD40 PF00400.27 CDI87545.1 - 1.3e-15 56.6 13.4 1.4e-05 24.8 1.2 6.2 6 1 0 6 6 6 4 WD domain, G-beta repeat Med15 PF09606.5 CDI87546.1 - 0.032 12.4 71.1 0.044 12.0 49.3 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Exonuc_VII_L PF02601.10 CDI87546.1 - 0.18 10.9 17.8 0.2 10.8 12.4 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit PLRV_ORF5 PF01690.12 CDI87546.1 - 0.38 9.8 11.9 0.43 9.6 8.2 1.2 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein LMBR1 PF04791.11 CDI87546.1 - 0.59 8.6 6.7 0.72 8.3 4.6 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein PAT1 PF09770.4 CDI87546.1 - 1.4 7.0 63.5 1.8 6.7 44.0 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 FAM60A PF15396.1 CDI87546.1 - 1.6 8.4 14.7 2.7 7.6 10.2 1.4 1 0 0 1 1 1 0 Protein Family FAM60A TMEM51 PF15345.1 CDI87546.1 - 1.7 8.2 21.0 3 7.4 14.6 1.4 1 0 0 1 1 1 0 Transmembrane protein 51 TFIIA PF03153.8 CDI87546.1 - 4.7 7.0 46.5 7.6 6.3 32.2 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Paramyxo_ncap PF00973.14 CDI87546.1 - 4.7 5.7 19.2 6.4 5.3 13.3 1.0 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Ala_racemase_N PF01168.15 CDI87547.1 - 5.8e-06 26.0 12.4 5.8e-06 26.0 8.6 2.5 2 2 0 2 2 1 1 Alanine racemase, N-terminal domain Peptidase_S49_N PF08496.5 CDI87547.1 - 0.0044 16.8 11.9 0.0078 16.0 8.2 1.4 1 0 0 1 1 1 1 Peptidase family S49 N-terminal Suf PF05843.9 CDI87547.1 - 0.005 16.5 9.9 0.0056 16.4 6.9 1.2 1 0 0 1 1 1 1 Suppressor of forked protein (Suf) PRTP PF01366.13 CDI87547.1 - 0.0063 14.5 7.9 0.007 14.4 5.5 1.2 1 0 0 1 1 1 1 Herpesvirus processing and transport protein Mre11_DNA_bind PF04152.9 CDI87547.1 - 0.1 12.4 13.5 0.1 12.4 8.6 1.4 1 1 0 1 1 1 0 Mre11 DNA-binding presumed domain BTV_NS2 PF04514.7 CDI87547.1 - 0.22 10.3 8.7 0.36 9.6 6.1 1.3 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 PBP_sp32 PF07222.7 CDI87547.1 - 0.34 10.0 15.0 0.51 9.4 10.4 1.3 1 0 0 1 1 1 0 Proacrosin binding protein sp32 FimP PF09766.4 CDI87547.1 - 0.45 9.5 21.8 0.58 9.1 15.1 1.1 1 0 0 1 1 1 0 Fms-interacting protein TUSC2 PF15000.1 CDI87547.1 - 0.54 10.3 6.9 1.1 9.3 4.8 1.5 1 0 0 1 1 1 0 Tumour suppressor candidate 2 DUF4220 PF13968.1 CDI87547.1 - 0.93 8.5 4.3 1.2 8.1 3.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4220) SpoVR PF04293.8 CDI87547.1 - 0.96 7.7 13.7 1.6 7.0 9.5 1.3 1 0 0 1 1 1 0 SpoVR like protein GAGA_bind PF06217.7 CDI87547.1 - 1.3 8.9 14.5 1.7 8.5 10.0 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family Folate_carrier PF01770.13 CDI87547.1 - 3 6.2 8.3 5.5 5.3 5.7 1.4 1 0 0 1 1 1 0 Reduced folate carrier DDHD PF02862.12 CDI87547.1 - 4.3 7.0 13.7 1.4 8.6 7.7 1.4 2 0 0 2 2 2 0 DDHD domain YjgP_YjgQ PF03739.9 CDI87547.1 - 5.2 5.6 7.3 6.9 5.2 5.1 1.2 1 0 0 1 1 1 0 Predicted permease YjgP/YjgQ family DUF4557 PF15101.1 CDI87547.1 - 5.3 6.8 21.5 9.8 5.9 14.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) Activator_LAG-3 PF11498.3 CDI87547.1 - 5.5 5.6 39.9 7.8 5.1 27.7 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 DivIC PF04977.10 CDI87547.1 - 6.4 6.3 22.4 22 4.6 15.5 1.9 1 0 0 1 1 1 0 Septum formation initiator AAA_23 PF13476.1 CDI87547.1 - 7.1 6.8 18.7 11 6.2 12.9 1.3 1 0 0 1 1 1 0 AAA domain CemA PF03040.9 CDI87547.1 - 9.1 5.8 8.6 13 5.2 6.0 1.2 1 0 0 1 1 1 0 CemA family DUF2215 PF10225.4 CDI87547.1 - 9.2 5.6 7.8 14 5.0 5.4 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) DUF912 PF06024.7 CDI87547.1 - 9.6 6.3 8.6 22 5.1 6.0 1.6 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Spore_coat_CotO PF14153.1 CDI87548.1 - 0.017 14.5 17.4 0.02 14.3 12.0 1.1 1 0 0 1 1 1 0 Spore coat protein CotO DUF1510 PF07423.6 CDI87548.1 - 0.02 14.2 14.2 0.021 14.1 9.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DUF3807 PF12720.2 CDI87548.1 - 0.036 14.2 16.4 0.034 14.2 11.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) NPR3 PF03666.8 CDI87548.1 - 0.072 11.6 16.1 0.079 11.4 11.1 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Rtf2 PF04641.7 CDI87548.1 - 0.14 11.3 24.3 0.16 11.1 16.9 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger Kei1 PF08552.6 CDI87548.1 - 0.26 10.9 1.5 0.29 10.7 1.0 1.0 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 Pox_Ag35 PF03286.9 CDI87548.1 - 0.33 10.4 22.4 0.36 10.3 15.5 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein FLO_LFY PF01698.11 CDI87548.1 - 0.36 9.6 16.1 0.41 9.4 11.2 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein DUF2413 PF10310.4 CDI87548.1 - 0.37 9.5 17.3 0.41 9.4 12.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) Tom22 PF04281.8 CDI87548.1 - 0.37 10.3 5.2 0.45 10.0 3.6 1.1 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 Pap_E4 PF02711.9 CDI87548.1 - 0.38 11.5 9.8 0.48 11.2 6.8 1.1 1 0 0 1 1 1 0 E4 protein Serinc PF03348.10 CDI87548.1 - 0.46 9.1 6.9 0.51 8.9 4.8 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) BatD PF13584.1 CDI87548.1 - 0.47 8.9 12.6 0.57 8.7 8.8 1.2 1 0 0 1 1 1 0 Oxygen tolerance SID-1_RNA_chan PF13965.1 CDI87548.1 - 0.49 8.4 3.1 0.53 8.3 2.2 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 FAM176 PF14851.1 CDI87548.1 - 0.6 9.7 7.2 0.81 9.3 5.0 1.2 1 0 0 1 1 1 0 FAM176 family RNA_pol_Rpc4 PF05132.9 CDI87548.1 - 0.64 10.0 14.4 0.73 9.8 10.0 1.1 1 0 0 1 1 1 0 RNA polymerase III RPC4 GAGA_bind PF06217.7 CDI87548.1 - 0.71 9.7 22.4 0.7 9.8 15.5 1.0 1 0 0 1 1 1 0 GAGA binding protein-like family Otopetrin PF03189.8 CDI87548.1 - 0.75 8.7 6.5 0.81 8.6 4.5 1.0 1 0 0 1 1 1 0 Otopetrin DUF3464 PF11947.3 CDI87548.1 - 0.79 9.1 16.7 0.94 8.9 11.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) PH_4 PF15404.1 CDI87548.1 - 0.99 8.8 13.5 1.1 8.7 9.4 1.1 1 0 0 1 1 1 0 Pleckstrin homology domain Ycf1 PF05758.7 CDI87548.1 - 1.1 6.8 17.8 1.3 6.6 12.3 1.0 1 0 0 1 1 1 0 Ycf1 Folate_carrier PF01770.13 CDI87548.1 - 1.3 7.4 8.8 1.4 7.3 6.1 1.0 1 0 0 1 1 1 0 Reduced folate carrier Afi1 PF07792.7 CDI87548.1 - 1.5 8.7 8.8 2 8.3 6.1 1.3 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Gti1_Pac2 PF09729.4 CDI87548.1 - 1.6 8.5 13.5 1.9 8.3 9.4 1.1 1 0 0 1 1 1 0 Gti1/Pac2 family DUF4512 PF14975.1 CDI87548.1 - 1.8 9.4 11.9 2.2 9.1 8.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4512) YMF19 PF02326.10 CDI87548.1 - 1.8 9.2 8.1 2.6 8.6 5.6 1.3 1 0 0 1 1 1 0 Plant ATP synthase F0 FHIPEP PF00771.15 CDI87548.1 - 1.9 6.7 6.1 2.2 6.5 4.2 1.2 1 0 0 1 1 1 0 FHIPEP family DUF3260 PF11658.3 CDI87548.1 - 1.9 6.4 4.9 2.1 6.4 3.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3260) LicD PF04991.8 CDI87548.1 - 2.3 8.2 14.9 2.5 8.1 10.3 1.0 1 0 0 1 1 1 0 LicD family DUF908 PF06012.7 CDI87548.1 - 2.6 7.2 10.5 2.8 7.1 7.3 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) Paramyxo_ncap PF00973.14 CDI87548.1 - 2.6 6.6 10.7 2.7 6.5 7.4 1.0 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein DUF1764 PF08576.5 CDI87548.1 - 2.7 8.7 26.0 3.5 8.4 18.0 1.1 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) Dala_Dala_lig_N PF01820.16 CDI87548.1 - 2.8 8.2 7.5 3.5 7.9 5.2 1.3 1 0 0 1 1 1 0 D-ala D-ala ligase N-terminus DUF4355 PF14265.1 CDI87548.1 - 3.4 7.6 39.3 3.9 7.4 27.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4355) Ctr PF04145.10 CDI87548.1 - 3.4 7.6 7.6 3.6 7.6 5.3 1.1 1 0 0 1 1 1 0 Ctr copper transporter family Di19_C PF14571.1 CDI87548.1 - 4.8 7.5 10.3 6.1 7.2 7.1 1.2 1 0 0 1 1 1 0 Stress-induced protein Di19, C-terminal AIF_C PF14721.1 CDI87548.1 - 4.8 7.4 10.5 5.7 7.2 7.3 1.1 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term OATP PF03137.15 CDI87548.1 - 5.1 5.0 11.3 5.6 4.8 7.8 1.0 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family DDHD PF02862.12 CDI87548.1 - 5.2 6.7 15.6 6.1 6.5 10.8 1.1 1 0 0 1 1 1 0 DDHD domain EIIBC-GUT_N PF03612.9 CDI87548.1 - 5.3 6.6 8.9 6 6.4 6.2 1.2 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Zip PF02535.17 CDI87548.1 - 6.1 5.7 6.4 7.2 5.5 4.4 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter eIF-3_zeta PF05091.7 CDI87548.1 - 6.3 5.3 18.0 6.9 5.1 12.5 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Hom_end_hint PF05203.11 CDI87548.1 - 6.4 6.4 11.7 6.9 6.3 8.1 1.0 1 0 0 1 1 1 0 Hom_end-associated Hint SET PF00856.23 CDI87548.1 - 6.8 6.9 6.0 7.4 6.8 4.2 1.1 1 0 0 1 1 1 0 SET domain Vfa1 PF08432.5 CDI87548.1 - 7.4 6.5 32.8 9.2 6.2 22.7 1.0 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 RNA_pol_Rpb1_5 PF04998.12 CDI87548.1 - 8 5.6 12.7 8.5 5.5 8.8 1.0 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 Nucleoside_tran PF01733.13 CDI87548.1 - 8.3 5.4 6.0 8.6 5.4 4.2 1.0 1 0 0 1 1 1 0 Nucleoside transporter DUF2828 PF11443.3 CDI87548.1 - 9.3 4.3 16.7 9.3 4.3 11.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Pex24p PF06398.6 CDI87548.1 - 9.6 4.8 10.7 9.9 4.8 7.4 1.1 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin IncA PF04156.9 CDI87549.1 - 2.1e-05 24.1 8.5 0.00038 20.1 7.4 16.1 12 5 1 13 13 13 2 IncA protein TFIIF_alpha PF05793.7 CDI87550.1 - 0.00049 18.5 34.5 0.00049 18.5 23.9 2.1 2 0 0 2 2 2 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) ETRAMP PF09716.5 CDI87550.1 - 0.01 15.7 5.2 0.01 15.7 3.6 4.6 4 1 0 4 4 4 0 Malarial early transcribed membrane protein (ETRAMP) DUF1510 PF07423.6 CDI87551.1 - 0.00019 20.8 18.4 0.00023 20.5 12.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) CDC45 PF02724.9 CDI87551.1 - 0.001 17.2 11.6 0.001 17.2 8.0 1.1 1 0 0 1 1 1 1 CDC45-like protein Maf PF02545.9 CDI87551.1 - 0.011 14.9 2.6 0.012 14.7 1.8 1.1 1 0 0 1 1 1 0 Maf-like protein DUF2052 PF09747.4 CDI87551.1 - 0.047 13.6 22.9 0.054 13.4 15.9 1.1 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) DUF3260 PF11658.3 CDI87551.1 - 0.051 11.7 17.0 0.06 11.4 11.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3260) YfhO PF09586.5 CDI87551.1 - 0.072 11.1 10.8 0.089 10.8 7.5 1.2 1 0 0 1 1 1 0 Bacterial membrane protein YfhO DUF1312 PF07009.6 CDI87551.1 - 0.087 12.6 6.7 0.12 12.2 4.2 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1312) Ycf1 PF05758.7 CDI87551.1 - 0.12 10.0 16.3 0.14 9.8 11.3 1.1 1 0 0 1 1 1 0 Ycf1 Rtf2 PF04641.7 CDI87551.1 - 0.17 11.0 16.6 0.19 10.8 11.5 1.2 1 0 0 1 1 1 0 Rtf2 RING-finger Herpes_DNAp_acc PF04929.7 CDI87551.1 - 0.38 9.6 14.7 0.42 9.5 10.2 1.0 1 0 0 1 1 1 0 Herpes DNA replication accessory factor DUF913 PF06025.7 CDI87551.1 - 0.44 9.2 10.8 0.52 9.0 7.5 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Neur_chan_memb PF02932.11 CDI87551.1 - 0.47 10.2 13.9 0.57 10.0 9.7 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Tmp39 PF10271.4 CDI87551.1 - 0.5 8.9 4.3 0.53 8.8 3.0 1.0 1 0 0 1 1 1 0 Putative transmembrane protein Presenilin PF01080.12 CDI87551.1 - 0.63 8.7 13.9 0.76 8.5 9.7 1.1 1 0 0 1 1 1 0 Presenilin Hid1 PF12722.2 CDI87551.1 - 0.67 7.5 19.0 0.72 7.4 13.1 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SID-1_RNA_chan PF13965.1 CDI87551.1 - 0.91 7.6 10.9 1.1 7.3 7.6 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Baculo_PP31 PF05311.6 CDI87551.1 - 1.3 8.2 18.5 1.6 7.9 12.8 1.2 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) DUF1980 PF09323.5 CDI87551.1 - 1.6 8.4 17.6 3.3 7.3 12.2 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF1980) DUF2215 PF10225.4 CDI87551.1 - 1.8 7.9 11.4 1.9 7.8 7.9 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) GAGA_bind PF06217.7 CDI87551.1 - 1.8 8.4 18.2 1.9 8.3 12.6 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family Band_3_cyto PF07565.8 CDI87551.1 - 1.9 7.9 22.2 2.8 7.3 15.4 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain AAA_11 PF13086.1 CDI87551.1 - 2.1 7.8 20.6 2.4 7.6 14.3 1.0 1 0 0 1 1 1 0 AAA domain Herpes_env PF01673.13 CDI87551.1 - 2.3 6.6 14.2 2.5 6.5 9.8 1.0 1 0 0 1 1 1 0 Herpesvirus putative major envelope glycoprotein DUF4045 PF13254.1 CDI87551.1 - 2.3 7.3 17.6 2.5 7.3 12.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) FLO_LFY PF01698.11 CDI87551.1 - 2.3 6.9 21.6 2.9 6.6 14.9 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein UPF0560 PF10577.4 CDI87551.1 - 2.5 6.2 26.7 2.7 6.1 18.5 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Oxidored_q1_C PF01010.14 CDI87551.1 - 2.7 7.4 8.6 3.3 7.1 6.0 1.1 1 0 0 1 1 1 0 NADH-Ubiquinone oxidoreductase (complex I) subunit C-terminus Gastrin PF00918.12 CDI87551.1 - 2.9 8.7 25.0 4.2 8.1 17.3 1.3 1 0 0 1 1 1 0 Gastrin/cholecystokinin family FAM91_C PF14648.1 CDI87551.1 - 3 6.5 11.0 3.3 6.4 7.6 1.1 1 0 0 1 1 1 0 FAM91 C-terminus DUF3537 PF12056.3 CDI87551.1 - 3.2 6.3 9.5 3.8 6.1 6.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3537) IRK PF01007.15 CDI87551.1 - 3.9 6.1 9.1 4.7 5.8 6.3 1.0 1 0 0 1 1 1 0 Inward rectifier potassium channel Paf1 PF03985.8 CDI87551.1 - 4.1 6.0 26.4 4.5 5.8 18.3 1.1 1 0 0 1 1 1 0 Paf1 TT_ORF1 PF02956.9 CDI87551.1 - 4.6 5.5 19.0 4.9 5.4 13.1 1.1 1 0 0 1 1 1 0 TT viral orf 1 DDHD PF02862.12 CDI87551.1 - 4.9 6.8 19.5 5.4 6.7 13.5 1.1 1 0 0 1 1 1 0 DDHD domain Hom_end_hint PF05203.11 CDI87551.1 - 5.3 6.7 14.8 7.4 6.2 10.3 1.3 1 0 0 1 1 1 0 Hom_end-associated Hint FliP PF00813.15 CDI87551.1 - 5.6 6.6 12.5 7.6 6.1 8.7 1.2 1 0 0 1 1 1 0 FliP family AAA_23 PF13476.1 CDI87551.1 - 5.8 7.1 28.2 7 6.9 19.5 1.1 1 0 0 1 1 1 0 AAA domain PPP4R2 PF09184.6 CDI87551.1 - 5.8 6.3 19.0 6.3 6.2 13.2 1.1 1 0 0 1 1 1 0 PPP4R2 CPSF100_C PF13299.1 CDI87551.1 - 6.9 6.8 22.8 7.4 6.7 15.8 1.1 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Peptidase_U57 PF05582.7 CDI87551.1 - 8.1 5.3 16.6 9.9 5.0 11.5 1.2 1 0 0 1 1 1 0 YabG peptidase U57 R_equi_Vir PF05526.6 CDI87551.1 - 8.6 5.9 8.6 11 5.5 6.0 1.3 1 0 0 1 1 1 0 Rhodococcus equi virulence-associated protein Rubella_E2 PF05749.6 CDI87552.1 - 0.042 13.1 0.7 0.074 12.2 0.5 1.4 1 0 0 1 1 1 0 Rubella membrane glycoprotein E2 SDA1 PF05285.7 CDI87553.1 - 0.025 13.8 54.8 0.031 13.5 38.0 1.1 1 0 0 1 1 1 0 SDA1 CCDC71L PF15374.1 CDI87553.1 - 7.5 5.7 24.3 7.5 5.7 16.9 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 71L Nucleoplasmin PF03066.10 CDI87554.1 - 0.0044 16.5 4.4 0.0058 16.1 3.1 1.2 1 0 0 1 1 1 1 Nucleoplasmin VID27 PF08553.5 CDI87554.1 - 0.011 13.9 1.8 0.011 13.9 1.2 1.1 1 0 0 1 1 1 0 VID27 cytoplasmic protein BSP_II PF05432.6 CDI87554.1 - 0.018 14.3 5.7 0.027 13.7 3.9 1.4 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) RAB3GAP2_N PF14655.1 CDI87554.1 - 0.021 13.8 1.1 0.028 13.4 0.7 1.1 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus ADP_ribosyl_GH PF03747.9 CDI87554.1 - 0.089 12.5 0.6 0.14 11.8 0.4 1.3 1 0 0 1 1 1 0 ADP-ribosylglycohydrolase DUF4366 PF14283.1 CDI87554.1 - 0.11 11.8 7.1 0.21 10.9 5.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4366) FAM176 PF14851.1 CDI87554.1 - 0.23 11.1 3.7 0.4 10.3 2.6 1.3 1 0 0 1 1 1 0 FAM176 family PEX11 PF05648.9 CDI87554.1 - 0.43 9.8 2.6 0.59 9.3 1.5 1.4 1 1 0 1 1 1 0 Peroxisomal biogenesis factor 11 (PEX11) DUF3235 PF11574.3 CDI87554.1 - 3.6 7.9 8.3 0.19 11.9 0.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3235) PBP1_TM PF14812.1 CDI87554.1 - 6.6 7.1 8.0 12 6.3 5.5 1.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal SOBP PF15279.1 CDI87555.1 - 1.1 9.5 31.3 1.6 9.0 21.7 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein WTX PF09422.5 CDI87555.1 - 2.1 7.2 30.0 2.8 6.8 20.8 1.1 1 0 0 1 1 1 0 WTX protein SUA5 PF03481.8 CDI87555.1 - 5.8 7.0 20.9 33 4.5 14.5 2.4 1 1 0 1 1 1 0 Putative GTP-binding controlling metal-binding PAT1 PF09770.4 CDI87555.1 - 6.1 4.9 66.2 7.6 4.6 45.9 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Med15 PF09606.5 CDI87555.1 - 9.3 4.3 79.7 12 3.9 55.3 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Dynactin_p62 PF05502.8 CDI87556.1 - 9.3e-08 31.2 20.8 9.3e-08 31.2 14.4 4.4 3 3 0 3 3 3 2 Dynactin p62 family FimP PF09766.4 CDI87556.1 - 0.0029 16.7 4.7 0.0029 16.7 3.3 3.2 3 0 0 3 3 3 3 Fms-interacting protein CD20 PF04103.10 CDI87556.1 - 0.061 13.2 0.2 0.061 13.2 0.2 3.8 3 2 1 4 4 4 0 CD20-like family IncA PF04156.9 CDI87556.1 - 0.23 11.0 37.1 0.032 13.8 5.3 4.2 3 0 0 3 3 3 0 IncA protein Peptidase_S49_N PF08496.5 CDI87556.1 - 2.1 8.0 16.5 3.9 7.2 2.5 4.0 4 0 0 4 4 4 0 Peptidase family S49 N-terminal Peptidase_M48 PF01435.13 CDI87558.1 - 5.8e-38 130.7 0.0 1.1e-37 129.7 0.0 1.4 2 0 0 2 2 2 1 Peptidase family M48 YihI PF04220.7 CDI87559.1 - 0.042 13.1 1.3 4.4 6.6 0.1 2.0 1 1 1 2 2 2 0 Der GTPase activator (YihI) DUF3564 PF12087.3 CDI87559.1 - 0.32 10.6 3.4 7.9 6.0 0.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3564) Activator_LAG-3 PF11498.3 CDI87561.1 - 0.53 8.9 18.8 0.94 8.1 13.0 1.4 1 0 0 1 1 1 0 Transcriptional activator LAG-3 UPF0560 PF10577.4 CDI87561.1 - 4.5 5.4 8.9 6.2 4.9 6.2 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 DUF1675 PF07897.6 CDI87562.1 - 0.1 12.4 44.0 0.15 11.9 30.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) Utp14 PF04615.8 CDI87562.1 - 0.12 10.5 52.7 0.15 10.2 36.5 1.1 1 0 0 1 1 1 0 Utp14 protein DUF572 PF04502.8 CDI87562.1 - 0.21 10.7 49.9 0.26 10.4 34.6 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Macoilin PF09726.4 CDI87562.1 - 0.49 8.6 51.0 0.8 7.9 35.3 1.3 1 0 0 1 1 1 0 Transmembrane protein TFIIA PF03153.8 CDI87562.1 - 9.1 6.0 80.0 12 5.7 55.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RNA_replicase_B PF03431.8 CDI87563.1 - 0.15 10.2 7.8 0.15 10.2 5.4 1.0 1 0 0 1 1 1 0 RNA replicase, beta-chain Pox_Ag35 PF03286.9 CDI87563.1 - 0.7 9.3 18.9 0.72 9.3 13.1 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DUF913 PF06025.7 CDI87563.1 - 1.4 7.6 16.6 1.7 7.3 11.5 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) NARP1 PF12569.3 CDI87563.1 - 1.9 7.1 25.8 2.1 6.9 17.9 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Rtf2 PF04641.7 CDI87563.1 - 2.6 7.1 27.1 3.2 6.8 18.8 1.3 1 0 0 1 1 1 0 Rtf2 RING-finger NPR3 PF03666.8 CDI87563.1 - 2.8 6.3 22.4 2.7 6.4 15.6 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF2413 PF10310.4 CDI87563.1 - 2.9 6.5 33.7 3.6 6.3 23.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) Tim54 PF11711.3 CDI87563.1 - 3.8 6.0 17.0 4.1 5.8 11.8 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Paf1 PF03985.8 CDI87563.1 - 3.8 6.1 33.5 4.2 6.0 23.2 1.1 1 0 0 1 1 1 0 Paf1 Zip PF02535.17 CDI87563.1 - 5.1 6.0 12.3 4.8 6.1 8.5 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter SelP_N PF04592.9 CDI87563.1 - 7.4 5.8 21.7 9.1 5.5 15.0 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region DDHD PF02862.12 CDI87563.1 - 7.6 6.2 28.7 8.8 6.0 19.9 1.1 1 0 0 1 1 1 0 DDHD domain Raftlin PF15250.1 CDI87563.1 - 8 4.8 23.8 8.3 4.8 16.5 1.1 1 0 0 1 1 1 0 Raftlin CobT PF06213.7 CDI87563.1 - 8.4 5.4 20.6 8.7 5.3 14.3 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Ribosomal_60s PF00428.14 CDI87564.1 - 0.0024 18.2 7.4 0.0024 18.2 5.2 5.4 3 1 1 4 4 4 1 60s Acidic ribosomal protein DUF2620 PF10941.3 CDI87564.1 - 0.075 13.0 6.6 0.18 11.8 0.9 2.8 3 0 0 3 3 3 0 Protein of unknown function DUF2620 Daxx PF03344.10 CDI87564.1 - 0.56 8.6 29.0 0.66 8.3 20.1 1.2 1 0 0 1 1 1 0 Daxx Family DUF605 PF04652.11 CDI87564.1 - 2 7.6 24.3 2.9 7.1 16.9 1.2 1 0 0 1 1 1 0 Vta1 like DUF3210 PF11489.3 CDI87564.1 - 8 5.0 39.3 10 4.6 27.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3210) NPR3 PF03666.8 CDI87565.1 - 0.06 11.8 8.8 0.059 11.8 6.1 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 AIF_C PF14721.1 CDI87565.1 - 0.38 11.0 9.6 0.47 10.7 6.7 1.3 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Trypan_PARP PF05887.6 CDI87565.1 - 0.51 10.1 29.5 0.7 9.6 20.4 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Herpes_MCP PF03122.9 CDI87565.1 - 0.63 7.2 3.8 0.65 7.2 2.6 1.0 1 0 0 1 1 1 0 Herpes virus major capsid protein Sec62 PF03839.11 CDI87565.1 - 0.84 8.9 12.3 0.91 8.8 8.5 1.0 1 0 0 1 1 1 0 Translocation protein Sec62 DUF913 PF06025.7 CDI87565.1 - 1.1 7.8 7.6 1.2 7.8 5.3 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) FAM60A PF15396.1 CDI87565.1 - 1.4 8.5 7.2 1.4 8.6 5.0 1.0 1 0 0 1 1 1 0 Protein Family FAM60A NESP55 PF06390.7 CDI87565.1 - 1.5 8.0 30.8 2.3 7.5 21.3 1.2 1 0 0 1 1 1 0 Neuroendocrine-specific golgi protein P55 (NESP55) TRAP_alpha PF03896.11 CDI87565.1 - 1.9 7.4 17.7 2.6 6.9 12.3 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Raftlin PF15250.1 CDI87565.1 - 2.2 6.6 12.9 2.4 6.5 9.0 1.0 1 0 0 1 1 1 0 Raftlin Zip PF02535.17 CDI87565.1 - 3.1 6.7 9.8 3.2 6.6 6.8 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Tim54 PF11711.3 CDI87565.1 - 3.5 6.1 17.9 4 5.9 12.4 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Tfb4 PF03850.9 CDI87565.1 - 3.7 6.7 5.6 4.1 6.5 3.9 1.0 1 0 0 1 1 1 0 Transcription factor Tfb4 DUF2052 PF09747.4 CDI87565.1 - 4.7 7.1 26.6 5.9 6.7 18.4 1.1 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) Neur_chan_memb PF02932.11 CDI87565.1 - 5 6.9 5.7 5.4 6.8 4.0 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region RP-C_C PF11800.3 CDI87565.1 - 5.1 6.7 12.4 6.1 6.4 8.6 1.1 1 0 0 1 1 1 0 Replication protein C C-terminal region Kei1 PF08552.6 CDI87565.1 - 6.6 6.3 6.1 7.9 6.0 4.2 1.1 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 DUF3537 PF12056.3 CDI87565.1 - 6.9 5.2 6.2 7 5.2 4.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3537) DHHW PF14286.1 CDI87565.1 - 6.9 5.8 15.2 8.3 5.6 10.5 1.1 1 0 0 1 1 1 0 DHHW protein Hom_end_hint PF05203.11 CDI87565.1 - 7.1 6.2 11.1 7.7 6.1 7.7 1.0 1 0 0 1 1 1 0 Hom_end-associated Hint SpoIIP PF07454.6 CDI87565.1 - 7.9 5.5 14.2 8.1 5.5 9.8 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Serinc PF03348.10 CDI87565.1 - 8.7 4.9 8.2 10 4.6 5.7 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) Suf PF05843.9 CDI87566.1 - 0.00011 22.1 21.0 0.0065 16.2 1.6 2.2 2 0 0 2 2 2 2 Suppressor of forked protein (Suf) Ribosomal_60s PF00428.14 CDI87566.1 - 0.00059 20.1 7.0 0.00059 20.1 4.9 4.6 3 2 0 3 3 1 1 60s Acidic ribosomal protein RAB3GAP2_N PF14655.1 CDI87566.1 - 0.0035 16.4 18.9 0.013 14.5 3.0 2.6 2 0 0 2 2 2 2 Rab3 GTPase-activating protein regulatory subunit N-terminus Serinc PF03348.10 CDI87566.1 - 0.007 15.1 10.6 0.11 11.1 2.1 2.2 2 0 0 2 2 2 2 Serine incorporator (Serinc) AAA_23 PF13476.1 CDI87566.1 - 0.01 16.1 18.4 0.18 12.1 4.3 2.2 2 0 0 2 2 2 0 AAA domain RNA_pol_Rpc4 PF05132.9 CDI87566.1 - 0.019 14.9 8.7 1.7 8.6 0.1 2.6 2 0 0 2 2 2 0 RNA polymerase III RPC4 Hid1 PF12722.2 CDI87566.1 - 0.035 11.7 11.2 0.15 9.7 3.6 2.1 2 0 0 2 2 2 0 High-temperature-induced dauer-formation protein Pex16 PF08610.5 CDI87566.1 - 0.037 13.0 16.7 0.086 11.8 1.9 2.1 2 0 0 2 2 2 0 Peroxisomal membrane protein (Pex16) DUF4484 PF14831.1 CDI87566.1 - 0.04 14.0 4.6 0.81 9.7 1.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4484) FHIPEP PF00771.15 CDI87566.1 - 0.061 11.6 13.7 0.061 11.6 0.8 2.4 2 0 0 2 2 2 0 FHIPEP family EPL1 PF10513.4 CDI87566.1 - 0.066 13.4 12.3 1.1 9.4 0.5 2.4 2 0 0 2 2 2 0 Enhancer of polycomb-like Dala_Dala_lig_N PF01820.16 CDI87566.1 - 0.094 13.0 10.0 1.4 9.2 0.7 2.6 2 0 0 2 2 2 0 D-ala D-ala ligase N-terminus zf-DHHC PF01529.15 CDI87566.1 - 0.1 12.0 11.7 0.88 8.9 0.2 2.2 2 0 0 2 2 2 0 DHHC palmitoyltransferase Peptidase_S49_N PF08496.5 CDI87566.1 - 0.1 12.4 15.1 0.33 10.7 3.4 2.3 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Afi1 PF07792.7 CDI87566.1 - 0.14 12.1 13.5 2.2 8.2 0.2 2.3 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Dynamin_N PF00350.18 CDI87566.1 - 0.17 11.7 8.0 0.43 10.3 0.1 2.3 2 0 0 2 2 2 0 Dynamin family eIF-3_zeta PF05091.7 CDI87566.1 - 0.22 10.1 24.4 0.043 12.4 7.1 2.1 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF1943 PF09172.6 CDI87566.1 - 0.23 10.2 7.6 2.2 7.0 1.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1943) PAT1 PF09770.4 CDI87566.1 - 0.51 8.5 50.4 1.1 7.4 12.1 2.2 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 Baculo_PP31 PF05311.6 CDI87566.1 - 0.55 9.4 11.9 1.9 7.6 0.6 2.2 2 0 0 2 2 2 0 Baculovirus 33KDa late protein (PP31) Na_trans_assoc PF06512.8 CDI87566.1 - 0.55 10.1 11.2 1 9.2 0.8 2.2 2 0 0 2 2 2 0 Sodium ion transport-associated Apc15p PF05841.6 CDI87566.1 - 0.65 10.7 25.0 2.3 8.9 8.3 2.7 2 0 0 2 2 2 0 Apc15p protein DUF912 PF06024.7 CDI87566.1 - 0.74 9.9 12.8 2.3 8.3 2.1 2.6 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF3408 PF11888.3 CDI87566.1 - 0.78 9.6 14.8 2.3 8.1 3.8 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3408) DUF2215 PF10225.4 CDI87566.1 - 0.82 9.0 12.7 1.7 8.0 1.7 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2215) FAM176 PF14851.1 CDI87566.1 - 0.9 9.2 9.8 5.3 6.7 3.1 2.3 2 0 0 2 2 2 0 FAM176 family RMP PF14996.1 CDI87566.1 - 0.93 9.4 17.1 0.98 9.3 2.2 2.3 2 0 0 2 2 2 0 Retinal Maintenance U1snRNP70_N PF12220.3 CDI87566.1 - 0.98 9.7 21.8 0.6 10.4 1.8 2.5 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal SpoIIP PF07454.6 CDI87566.1 - 1.2 8.2 12.0 1.5 7.9 0.4 2.2 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) OATP PF03137.15 CDI87566.1 - 1.5 6.7 10.2 1.4 6.8 0.1 2.2 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family PRP3 PF08572.5 CDI87566.1 - 1.7 7.9 25.0 3 7.1 3.4 2.3 2 0 0 2 2 2 0 pre-mRNA processing factor 3 (PRP3) Folliculin PF11704.3 CDI87566.1 - 1.8 8.1 12.0 1.2 8.7 0.4 2.3 2 0 0 2 2 2 0 Vesicle coat protein involved in Golgi to plasma membrane transport CRF1 PF10380.4 CDI87566.1 - 2 8.7 9.2 6.9 7.0 0.2 2.3 2 0 0 2 2 2 0 Transcription factor CRF1 Spore_YhcN_YlaJ PF09580.5 CDI87566.1 - 2.1 8.4 14.8 4.3 7.4 0.5 2.2 2 0 0 2 2 2 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) Rxt3 PF08642.5 CDI87566.1 - 2.4 8.4 7.1 8.2 6.7 0.1 2.4 2 0 0 2 2 2 0 Histone deacetylation protein Rxt3 GOLD_2 PF13897.1 CDI87566.1 - 2.6 8.2 6.7 9.6 6.4 0.9 2.4 2 0 0 2 2 2 0 Golgi-dynamics membrane-trafficking Agouti PF05039.7 CDI87566.1 - 2.9 8.3 12.7 6.4 7.1 2.3 2.7 2 0 0 2 2 2 0 Agouti protein CPSF100_C PF13299.1 CDI87566.1 - 3.2 7.9 14.6 9.5 6.3 4.5 2.4 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal HD-ZIP_N PF04618.7 CDI87566.1 - 3.3 8.2 5.9 21 5.6 0.2 2.5 2 0 0 2 2 2 0 HD-ZIP protein N terminus MDFI PF15316.1 CDI87566.1 - 3.6 7.5 9.6 2.8 7.8 1.8 2.5 2 0 0 2 2 2 0 MyoD family inhibitor DUF4557 PF15101.1 CDI87566.1 - 4.2 7.1 35.5 5.8 6.6 10.8 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4557) BORG_CEP PF14957.1 CDI87566.1 - 4.7 8.1 11.9 10 7.0 3.5 2.5 2 0 0 2 2 2 0 Cdc42 effector 2OG-FeII_Oxy_5 PF13759.1 CDI87566.1 - 4.8 7.5 7.1 7.8 6.8 0.3 2.4 2 0 0 2 2 2 0 Putative 2OG-Fe(II) oxygenase Kin17_mid PF10357.4 CDI87566.1 - 4.9 6.8 18.8 4.8 6.8 2.6 2.4 2 0 0 2 2 2 0 Domain of Kin17 curved DNA-binding protein FAM60A PF15396.1 CDI87566.1 - 6.5 6.4 13.7 7 6.3 3.5 2.3 2 0 0 2 2 2 0 Protein Family FAM60A DUF4045 PF13254.1 CDI87566.1 - 7.2 5.7 17.3 4.2 6.5 6.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4045) DUF2149 PF09919.4 CDI87566.1 - 7.7 6.6 12.5 7.8 6.6 0.6 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2149) Ycf1 PF05758.7 CDI87566.1 - 7.7 4.0 16.8 2.8 5.5 4.9 2.0 2 0 0 2 2 2 0 Ycf1 DUF1675 PF07897.6 CDI87566.1 - 8.4 6.1 12.2 2.7 7.7 3.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1675) DUF2347 PF09804.4 CDI87566.1 - 8.5 5.5 10.6 9.4 5.4 1.9 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2347) DUF4518 PF15008.1 CDI87566.1 - 9.8 5.1 23.3 0.18 10.7 3.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4518) FNIP_N PF14636.1 CDI87567.1 - 0.02 15.3 5.9 0.022 15.2 4.1 1.1 1 0 0 1 1 1 0 Folliculin-interacting protein N-terminus AAA_23 PF13476.1 CDI87567.1 - 0.022 15.1 10.3 0.022 15.0 7.1 1.1 1 0 0 1 1 1 0 AAA domain Suf PF05843.9 CDI87567.1 - 0.034 13.8 9.3 0.032 13.9 6.5 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) APG6 PF04111.7 CDI87567.1 - 0.049 12.6 12.6 0.055 12.5 8.7 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF4175 PF13779.1 CDI87567.1 - 0.072 10.7 25.8 0.075 10.7 17.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) PAT1 PF09770.4 CDI87567.1 - 0.088 11.0 20.6 0.083 11.1 14.3 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 FimP PF09766.4 CDI87567.1 - 0.12 11.4 14.5 0.12 11.3 10.1 1.0 1 0 0 1 1 1 0 Fms-interacting protein Rep_4 PF05797.6 CDI87567.1 - 0.23 10.1 6.2 0.21 10.2 4.3 1.0 1 0 0 1 1 1 0 Yeast trans-acting factor (REP1/REP2) Peptidase_S64 PF08192.6 CDI87567.1 - 0.23 9.7 6.1 0.23 9.7 4.2 1.0 1 0 0 1 1 1 0 Peptidase family S64 Med15 PF09606.5 CDI87567.1 - 0.28 9.3 41.6 0.33 9.1 28.8 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Peptidase_C58 PF03543.9 CDI87567.1 - 0.31 10.4 13.4 0.32 10.4 9.3 1.2 1 0 0 1 1 1 0 Yersinia/Haemophilus virulence surface antigen HemX PF04375.9 CDI87567.1 - 0.34 9.4 30.2 0.41 9.1 21.0 1.0 1 0 0 1 1 1 0 HemX MRP-S26 PF14943.1 CDI87567.1 - 0.38 10.2 10.8 0.47 10.0 7.5 1.1 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 VIT1 PF01988.14 CDI87567.1 - 0.39 10.1 14.3 0.67 9.4 9.9 1.4 1 1 0 1 1 1 0 VIT family DUF3450 PF11932.3 CDI87567.1 - 0.39 9.9 27.1 0.48 9.6 18.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Bap31 PF05529.7 CDI87567.1 - 0.83 9.0 10.3 0.87 9.0 7.2 1.2 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like Mnd1 PF03962.10 CDI87567.1 - 1 8.9 14.8 1.3 8.6 10.3 1.1 1 0 0 1 1 1 0 Mnd1 family Macoilin PF09726.4 CDI87567.1 - 1.2 7.3 11.6 1.3 7.2 8.0 1.0 1 0 0 1 1 1 0 Transmembrane protein DUF2034 PF10356.4 CDI87567.1 - 1.3 8.1 7.6 1.8 7.7 5.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2034) Chloroplast_duf PF14476.1 CDI87567.1 - 1.3 7.7 15.6 1.5 7.5 10.8 1.0 1 0 0 1 1 1 0 Petal formation-expressed Neur_chan_memb PF02932.11 CDI87567.1 - 1.4 8.7 4.2 1.4 8.7 2.9 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Band_3_cyto PF07565.8 CDI87567.1 - 1.5 8.2 10.0 1.8 8.0 6.9 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain R_equi_Vir PF05526.6 CDI87567.1 - 1.7 8.2 9.7 2.3 7.8 6.7 1.3 1 0 0 1 1 1 0 Rhodococcus equi virulence-associated protein DUF844 PF05815.6 CDI87567.1 - 1.7 7.3 10.7 2.6 6.8 7.4 1.3 1 1 0 1 1 1 0 Baculovirus protein of unknown function (DUF844) Peptidase_S15 PF02129.13 CDI87567.1 - 1.7 7.9 10.6 2 7.7 7.4 1.0 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Serinc PF03348.10 CDI87567.1 - 2.2 6.9 8.6 2.1 6.9 6.0 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) DUF775 PF05603.7 CDI87567.1 - 2.6 7.5 11.6 2.7 7.4 8.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF775) Presenilin PF01080.12 CDI87567.1 - 2.6 6.7 7.1 2.8 6.6 4.9 1.0 1 0 0 1 1 1 0 Presenilin DUF1764 PF08576.5 CDI87567.1 - 2.7 8.8 10.7 3.8 8.3 7.4 1.2 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) MSP1_C PF07462.6 CDI87567.1 - 2.9 6.1 11.9 3.3 5.9 8.2 1.1 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus DDHD PF02862.12 CDI87567.1 - 2.9 7.6 8.1 3 7.5 5.6 1.1 1 0 0 1 1 1 0 DDHD domain DOR PF14839.1 CDI87567.1 - 2.9 7.5 16.7 3.5 7.3 11.5 1.1 1 0 0 1 1 1 0 DOR family FLO_LFY PF01698.11 CDI87567.1 - 3 6.5 10.7 3.3 6.4 7.4 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein DUF2203 PF09969.4 CDI87567.1 - 3.2 7.9 9.1 4.8 7.4 6.3 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) SprA-related PF12118.3 CDI87567.1 - 3.8 6.7 30.8 5.1 6.3 21.4 1.1 1 0 0 1 1 1 0 SprA-related family PMSI1 PF15322.1 CDI87567.1 - 4.3 6.3 11.6 5.1 6.0 8.1 1.1 1 0 0 1 1 1 0 Protein missing in infertile sperm 1, putative DUF4557 PF15101.1 CDI87567.1 - 4.4 7.0 17.6 5.6 6.7 12.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) Bud13 PF09736.4 CDI87567.1 - 4.4 7.5 15.7 5.7 7.2 10.9 1.1 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex RR_TM4-6 PF06459.7 CDI87567.1 - 4.4 7.1 9.8 4.5 7.0 6.8 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 ZYG-11_interact PF05884.7 CDI87567.1 - 4.4 6.2 15.8 5.2 6.0 11.0 1.0 1 0 0 1 1 1 0 Interactor of ZYG-11 DUF3371 PF11851.3 CDI87567.1 - 4.9 7.8 17.0 6.2 7.5 11.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3371) Gag_spuma PF03276.9 CDI87567.1 - 5.2 5.2 21.9 5.9 5.0 15.2 1.1 1 0 0 1 1 1 0 Spumavirus gag protein Sec62 PF03839.11 CDI87567.1 - 5.5 6.3 7.4 6.1 6.1 5.1 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 DOG1 PF14144.1 CDI87567.1 - 6.4 6.8 6.1 19 5.3 4.2 1.9 1 1 0 1 1 1 0 Seed dormancy control DUF2232 PF09991.4 CDI87567.1 - 6.4 5.6 6.6 8.5 5.2 4.6 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) MDFI PF15316.1 CDI87567.1 - 7.2 6.5 6.8 7.9 6.4 4.7 1.1 1 0 0 1 1 1 0 MyoD family inhibitor DUF3373 PF11853.3 CDI87567.1 - 7.7 4.9 14.3 11 4.3 9.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) CRF1 PF10380.4 CDI87567.1 - 9.9 6.5 7.6 13 6.1 5.3 1.2 1 0 0 1 1 1 0 Transcription factor CRF1 FYRN PF05964.9 CDI87568.1 - 0.074 12.5 0.0 0.23 10.9 0.0 1.8 1 0 0 1 1 1 0 F/Y-rich N-terminus IMS PF00817.15 CDI87572.1 - 2.5e-31 108.4 0.0 4.7e-31 107.6 0.0 1.4 1 0 0 1 1 1 1 impB/mucB/samB family RR_TM4-6 PF06459.7 CDI87572.1 - 0.12 12.1 4.7 0.2 11.5 3.2 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Pex14_N PF04695.8 CDI87572.1 - 0.32 11.0 14.7 0.72 9.9 10.2 1.6 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region BRF1 PF07741.8 CDI87572.1 - 1 9.6 9.6 1.9 8.7 6.7 1.3 1 0 0 1 1 1 0 Brf1-like TBP-binding domain DUF4175 PF13779.1 CDI87572.1 - 1.1 6.8 31.1 1.8 6.1 21.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Suf PF05843.9 CDI87572.1 - 1.1 8.9 14.9 1.7 8.3 10.3 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Band_3_cyto PF07565.8 CDI87572.1 - 1.2 8.6 9.1 1.7 8.1 6.3 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain DDHD PF02862.12 CDI87572.1 - 1.2 8.8 7.2 1.8 8.2 5.0 1.2 1 0 0 1 1 1 0 DDHD domain RIC3 PF15361.1 CDI87572.1 - 1.8 8.7 12.5 4.8 7.4 8.6 1.7 1 0 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 Ebola_NP PF05505.7 CDI87572.1 - 2.1 6.3 12.3 3 5.8 8.5 1.1 1 0 0 1 1 1 0 Ebola nucleoprotein eIF-3_zeta PF05091.7 CDI87572.1 - 3.3 6.2 13.3 4.6 5.7 9.2 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF4557 PF15101.1 CDI87572.1 - 6.1 6.6 20.7 9.3 6.0 14.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) FimP PF09766.4 CDI87572.1 - 6.4 5.7 22.7 9.1 5.2 15.7 1.1 1 0 0 1 1 1 0 Fms-interacting protein Pex16 PF08610.5 CDI87572.1 - 6.6 5.6 10.0 10 5.0 6.9 1.2 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) DUF4407 PF14362.1 CDI87572.1 - 8.3 5.2 18.0 12 4.7 12.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Spt20 PF12090.3 CDI87572.1 - 10 5.4 14.6 18 4.6 10.1 1.3 1 0 0 1 1 1 0 Spt20 family DUF4557 PF15101.1 CDI87573.1 - 6.2 6.6 10.7 27 4.5 5.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4557) Hid1 PF12722.2 CDI87575.1 - 0.2 9.3 37.1 0.22 9.1 25.7 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Nop14 PF04147.7 CDI87575.1 - 1.8 6.3 18.1 2.1 6.1 12.5 1.0 1 0 0 1 1 1 0 Nop14-like family UPF0560 PF10577.4 CDI87575.1 - 4.4 5.4 23.2 5 5.2 16.1 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 LpxB PF02684.10 CDI87576.1 - 0.0094 14.6 1.7 0.032 12.8 1.2 1.9 1 0 0 1 1 1 1 Lipid-A-disaccharide synthetase Folate_carrier PF01770.13 CDI87576.1 - 0.11 10.9 7.0 0.06 11.8 1.0 2.7 3 0 0 3 3 3 0 Reduced folate carrier Plasmodium_Vir PF05795.6 CDI87576.1 - 0.87 8.7 5.4 3.2 6.8 0.4 2.9 3 0 0 3 3 3 0 Plasmodium vivax Vir protein zf-DHHC PF01529.15 CDI87576.1 - 2.2 7.6 17.5 0.014 14.8 1.7 3.4 4 0 0 4 4 4 0 DHHC palmitoyltransferase SR-25 PF10500.4 CDI87577.1 - 0.004 16.6 20.2 0.004 16.6 14.0 5.3 4 2 1 6 6 6 2 Nuclear RNA-splicing-associated protein zf-C4H2 PF10146.4 CDI87578.1 - 0.023 14.6 1.7 0.023 14.7 1.2 1.2 1 0 0 1 1 1 0 Zinc finger-containing protein CDC27 PF09507.5 CDI87578.1 - 1.9 7.6 9.4 2.5 7.2 6.5 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 DUF1675 PF07897.6 CDI87579.1 - 0.25 11.1 14.2 0.27 11.0 9.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) DUF1510 PF07423.6 CDI87579.1 - 2.8 7.2 20.6 2.9 7.1 14.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) FAM60A PF15396.1 CDI87579.1 - 5.5 6.6 19.0 5.8 6.6 13.2 1.0 1 0 0 1 1 1 0 Protein Family FAM60A Rtf2 PF04641.7 CDI87579.1 - 6.7 5.8 21.1 7.1 5.7 14.6 1.0 1 0 0 1 1 1 0 Rtf2 RING-finger Paf1 PF03985.8 CDI87579.1 - 8.9 4.9 22.1 9.3 4.8 15.3 1.0 1 0 0 1 1 1 0 Paf1 Activator_LAG-3 PF11498.3 CDI87580.1 - 0.0022 16.8 7.9 0.0022 16.8 5.5 8.2 6 2 2 9 9 9 2 Transcriptional activator LAG-3 IncA PF04156.9 CDI87581.1 - 0.0083 15.7 10.5 0.0083 15.7 7.2 1.7 2 0 0 2 2 2 1 IncA protein AAA_10 PF12846.2 CDI87581.1 - 0.031 13.7 0.2 0.033 13.6 0.1 1.1 1 0 0 1 1 1 0 AAA-like domain UBN2 PF14223.1 CDI87581.1 - 0.041 13.6 1.0 0.07 12.9 0.7 1.3 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type WGG PF10273.4 CDI87581.1 - 0.061 13.4 0.5 0.13 12.4 0.4 1.5 1 0 0 1 1 1 0 Pre-rRNA-processing protein TSR2 DUF3584 PF12128.3 CDI87581.1 - 0.19 8.9 13.8 0.22 8.8 9.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF1980 PF09323.5 CDI87581.1 - 0.3 10.8 2.9 0.41 10.3 2.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) RRN3 PF05327.6 CDI87581.1 - 0.49 8.4 5.9 0.63 8.0 4.1 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Peptidase_S64 PF08192.6 CDI87581.1 - 0.66 8.2 5.1 1.1 7.5 3.5 1.3 1 0 0 1 1 1 0 Peptidase family S64 DUF1564 PF07600.6 CDI87581.1 - 0.86 8.9 4.6 0.66 9.2 0.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1564) SpaB_C PF14028.1 CDI87581.1 - 0.87 9.0 16.2 1.2 8.6 11.3 1.2 1 0 0 1 1 1 0 SpaB C-terminal domain AbiH PF14253.1 CDI87581.1 - 0.95 9.0 4.1 1.2 8.6 2.9 1.1 1 0 0 1 1 1 0 Bacteriophage abortive infection AbiH His_Phos_2 PF00328.17 CDI87581.1 - 1.1 8.4 5.7 1.7 7.9 4.0 1.2 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 2) Tox-PL PF15644.1 CDI87581.1 - 1.5 9.5 6.3 3.7 8.3 1.6 2.4 2 1 0 2 2 2 0 Papain fold toxin 1 FAP PF07174.6 CDI87581.1 - 3 7.0 18.3 0.28 10.4 9.8 1.4 2 0 0 2 2 2 0 Fibronectin-attachment protein (FAP) AAA_23 PF13476.1 CDI87581.1 - 3.7 7.8 10.8 5.3 7.3 7.5 1.2 1 0 0 1 1 1 0 AAA domain Herpes_UL25 PF01499.11 CDI87581.1 - 4 5.6 17.8 8.8 4.5 12.2 1.7 1 1 0 1 1 1 0 Herpesvirus UL25 family NICE-3 PF07406.6 CDI87581.1 - 4.8 6.6 6.7 0.42 10.1 0.4 1.9 2 0 0 2 2 2 0 NICE-3 protein Neur_chan_memb PF02932.11 CDI87581.1 - 5.2 6.8 5.6 15 5.3 3.9 1.8 1 1 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region SNARE PF05739.14 CDI87582.1 - 2.9e-16 58.9 2.5 2.9e-16 58.9 1.7 1.4 2 0 0 2 2 1 1 SNARE domain DUF386 PF04074.7 CDI87582.1 - 0.0043 16.5 0.3 0.0054 16.2 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF386) Ribosomal_L20 PF00453.13 CDI87582.1 - 0.0049 16.7 1.1 0.29 11.0 0.1 2.1 2 0 0 2 2 2 1 Ribosomal protein L20 DUF1515 PF07439.6 CDI87582.1 - 0.0063 16.3 1.2 0.0078 16.0 0.8 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1515) MCPsignal PF00015.16 CDI87582.1 - 0.0071 15.9 0.7 0.0081 15.7 0.5 1.1 1 0 0 1 1 1 1 Methyl-accepting chemotaxis protein (MCP) signalling domain Reo_sigmaC PF04582.7 CDI87582.1 - 0.0081 15.3 0.1 0.0089 15.2 0.1 1.1 1 0 0 1 1 1 1 Reovirus sigma C capsid protein DUF912 PF06024.7 CDI87582.1 - 0.015 15.3 0.7 0.024 14.7 0.3 1.4 1 1 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Tweety PF04906.8 CDI87582.1 - 0.025 13.0 2.5 0.026 12.9 1.7 1.0 1 0 0 1 1 1 0 Tweety DUF846 PF05832.7 CDI87582.1 - 0.025 14.3 0.2 0.037 13.7 0.2 1.3 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF846) Rifin_STEVOR PF02009.11 CDI87582.1 - 0.034 13.8 0.8 0.036 13.7 0.6 1.1 1 0 0 1 1 1 0 Rifin/stevor family EMP24_GP25L PF01105.19 CDI87582.1 - 0.054 13.2 4.3 0.088 12.5 3.0 1.4 1 1 0 1 1 1 0 emp24/gp25L/p24 family/GOLD Viral_env_E26 PF11050.3 CDI87582.1 - 0.055 12.6 1.2 0.063 12.4 0.8 1.0 1 0 0 1 1 1 0 Virus envelope protein E26 Fusion_gly PF00523.13 CDI87582.1 - 0.057 11.4 1.0 0.071 11.1 0.6 1.2 1 1 0 1 1 1 0 Fusion glycoprotein F0 PBP1_TM PF14812.1 CDI87582.1 - 0.061 13.6 0.2 0.071 13.4 0.2 1.4 1 1 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal 7tm_1 PF00001.16 CDI87582.1 - 0.062 12.4 0.3 0.061 12.4 0.2 1.1 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) DUF4079 PF13301.1 CDI87582.1 - 0.066 13.2 0.5 0.075 13.0 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4079) Mit_KHE1 PF10173.4 CDI87582.1 - 0.073 12.9 0.4 0.09 12.6 0.3 1.3 1 1 0 1 1 1 0 Mitochondrial K+-H+ exchange-related DUF357 PF04010.8 CDI87582.1 - 0.074 12.7 0.2 0.1 12.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF357) DUF3708 PF12501.3 CDI87582.1 - 0.088 12.6 2.8 0.13 12.0 1.9 1.3 1 1 0 1 1 1 0 Phosphate ATP-binding cassette transporter DUF607 PF04678.8 CDI87582.1 - 0.088 12.7 1.6 0.11 12.3 1.1 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF607 DUF2116 PF09889.4 CDI87582.1 - 0.093 12.5 0.6 0.18 11.6 0.4 1.5 1 0 0 1 1 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) DUF3899 PF13038.1 CDI87582.1 - 0.094 12.8 0.4 0.16 12.1 0.2 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF3899) RasGAP_C PF03836.10 CDI87582.1 - 0.098 12.3 2.7 0.12 12.0 1.9 1.1 1 0 0 1 1 1 0 RasGAP C-terminus DUF3753 PF12575.3 CDI87582.1 - 0.1 12.4 0.5 0.15 11.8 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3753) T2SF PF00482.18 CDI87582.1 - 0.18 11.6 5.0 0.76 9.6 3.5 1.8 1 1 0 1 1 1 0 Type II secretion system (T2SS), protein F GP41 PF00517.12 CDI87582.1 - 0.27 10.7 7.1 4.1 6.9 2.1 2.2 1 1 1 2 2 2 0 Retroviral envelope protein ADIP PF11559.3 CDI87582.1 - 0.56 10.0 6.0 0.86 9.4 4.2 1.3 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Synaptobrevin PF00957.16 CDI87582.1 - 0.61 9.7 4.7 0.85 9.2 3.0 1.5 1 1 0 1 1 1 0 Synaptobrevin FliJ PF02050.11 CDI87582.1 - 1.4 8.9 12.5 2.6 8.1 8.7 1.4 1 1 0 1 1 1 0 Flagellar FliJ protein DUF2562 PF10814.3 CDI87582.1 - 1.5 8.7 4.2 7.6 6.4 2.9 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2562) OEP PF02321.13 CDI87582.1 - 1.7 8.2 9.6 2.4 7.6 6.6 1.2 1 0 0 1 1 1 0 Outer membrane efflux protein THOC7 PF05615.8 CDI87582.1 - 2 8.6 6.8 4.4 7.5 4.7 1.5 1 1 0 1 1 1 0 Tho complex subunit 7 PspA_IM30 PF04012.7 CDI87582.1 - 3 7.1 11.1 11 5.2 7.7 1.8 1 1 0 1 1 1 0 PspA/IM30 family SR-25 PF10500.4 CDI87583.1 - 0.0036 16.8 48.0 0.0048 16.4 18.7 2.6 2 0 0 2 2 2 2 Nuclear RNA-splicing-associated protein DUF4614 PF15391.1 CDI87583.1 - 0.011 15.5 5.4 0.011 15.5 3.7 3.3 3 1 0 3 3 3 0 Domain of unknown function (DUF4614) SPX PF03105.14 CDI87583.1 - 0.87 9.3 23.9 2.5 7.7 13.6 2.2 2 0 0 2 2 2 0 SPX domain Macoilin PF09726.4 CDI87583.1 - 2.2 6.4 35.0 0.22 9.7 3.9 2.6 2 0 0 2 2 2 0 Transmembrane protein DUF572 PF04502.8 CDI87583.1 - 3.2 6.9 34.6 0.28 10.3 18.2 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF572) AAA_23 PF13476.1 CDI87583.1 - 5 7.4 17.4 8.3 6.6 12.1 1.4 1 0 0 1 1 1 0 AAA domain Profilin PF00235.14 CDI87585.1 - 3.3e-10 40.1 0.3 5.9e-10 39.2 0.2 1.4 1 1 0 1 1 1 1 Profilin Peptidase_C25_C PF03785.9 CDI87585.1 - 0.086 12.6 0.0 2.4 8.0 0.0 2.3 2 0 0 2 2 2 0 Peptidase family C25, C terminal ig-like domain RskA PF10099.4 CDI87587.1 - 0.5 10.0 41.9 0.19 11.4 1.3 3.8 2 1 2 4 4 4 0 Anti-sigma-K factor rskA Tetraspannin PF00335.15 CDI87587.1 - 0.61 9.3 6.0 0.52 9.5 0.4 3.0 1 1 1 2 2 2 0 Tetraspanin family SprA-related PF12118.3 CDI87587.1 - 2.8 7.1 67.5 0.044 13.1 12.6 3.1 3 0 0 3 3 3 0 SprA-related family FKS1_dom1 PF14288.1 CDI87587.1 - 5.8 6.8 8.4 0.84 9.5 0.3 2.7 3 0 0 3 3 3 0 1,3-beta-glucan synthase subunit FKS1, domain-1 Robl_LC7 PF03259.12 CDI87588.1 - 0.33 10.5 4.0 2 8.0 0.1 2.4 2 0 0 2 2 2 0 Roadblock/LC7 domain Med15 PF09606.5 CDI87588.1 - 0.65 8.1 53.3 0.83 7.7 36.9 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal PAT1 PF09770.4 CDI87588.1 - 1.9 6.6 41.0 2.6 6.1 28.4 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Ribosomal_60s PF00428.14 CDI87588.1 - 3.6 8.0 16.3 2.8 8.3 5.1 2.4 2 0 0 2 2 2 0 60s Acidic ribosomal protein Ribosomal_60s PF00428.14 CDI87589.1 - 0.62 10.5 15.5 0.067 13.5 5.5 2.5 2 0 0 2 2 2 0 60s Acidic ribosomal protein RskA PF10099.4 CDI87590.1 - 0.016 14.9 34.0 0.18 11.4 6.7 2.2 2 0 0 2 2 2 0 Anti-sigma-K factor rskA MFMR PF07777.6 CDI87590.1 - 0.7 9.7 11.2 0.15 11.9 5.3 1.6 2 0 0 2 2 2 0 G-box binding protein MFMR Cwf_Cwc_15 PF04889.7 CDI87590.1 - 0.73 9.5 11.4 0.33 10.6 6.0 1.7 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein DUF4079 PF13301.1 CDI87590.1 - 1.6 8.6 9.9 3.1 7.7 0.6 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF4079) APC_CDC26 PF10471.4 CDI87591.1 - 0.052 14.2 0.3 0.052 14.2 0.2 6.0 5 2 1 6 6 6 0 Anaphase-promoting complex APC subunit 1 DUF2029 PF09594.5 CDI87591.1 - 0.22 10.9 0.1 0.22 10.9 0.1 4.1 2 1 1 3 3 3 0 Protein of unknown function (DUF2029) DUF4448 PF14610.1 CDI87592.1 - 0.041 13.3 0.8 0.058 12.8 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) VWA PF00092.23 CDI87592.1 - 0.049 13.3 2.7 0.16 11.6 0.1 2.0 1 1 1 2 2 2 0 von Willebrand factor type A domain Nop14 PF04147.7 CDI87592.1 - 0.39 8.5 28.7 0.56 8.0 19.9 1.2 1 0 0 1 1 1 0 Nop14-like family DUF912 PF06024.7 CDI87592.1 - 0.53 10.3 2.2 1 9.4 0.8 2.1 1 1 1 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Spc7_N PF15402.1 CDI87592.1 - 0.8 7.6 23.0 0.9 7.4 15.9 1.0 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 CRF1 PF10380.4 CDI87594.1 - 0.22 11.8 8.7 0.28 11.5 6.0 1.1 1 0 0 1 1 1 0 Transcription factor CRF1 FimP PF09766.4 CDI87594.1 - 0.33 9.9 22.6 0.32 9.9 15.6 1.1 1 0 0 1 1 1 0 Fms-interacting protein BLVR PF06375.6 CDI87594.1 - 0.36 10.6 13.8 0.38 10.5 9.6 1.2 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) Sugar_tr PF00083.19 CDI87594.1 - 0.5 8.8 4.3 0.54 8.7 3.0 1.0 1 0 0 1 1 1 0 Sugar (and other) transporter SeqA PF03925.8 CDI87594.1 - 1.2 8.7 11.6 1.2 8.7 8.1 1.1 1 0 0 1 1 1 0 SeqA protein DUF4175 PF13779.1 CDI87594.1 - 1.8 6.1 33.6 1.7 6.2 23.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) SprA-related PF12118.3 CDI87594.1 - 2.1 7.6 30.0 2 7.6 20.8 1.0 1 0 0 1 1 1 0 SprA-related family DUF912 PF06024.7 CDI87594.1 - 2.2 8.3 8.3 2.6 8.1 5.8 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) ATAD4 PF15321.1 CDI87594.1 - 2.3 9.2 13.9 2.9 8.9 9.6 1.2 1 0 0 1 1 1 0 ATPase family AAA domain containing 4 DUF2201_N PF13203.1 CDI87594.1 - 2.4 7.2 14.4 2.5 7.1 10.0 1.0 1 0 0 1 1 1 0 Putative metallopeptidase domain AUX_IAA PF02309.11 CDI87594.1 - 2.7 7.6 14.8 3 7.5 10.2 1.0 1 0 0 1 1 1 0 AUX/IAA family Peptidase_S49_N PF08496.5 CDI87594.1 - 2.8 7.7 15.2 2.9 7.6 10.5 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Spore_coat_CotO PF14153.1 CDI87594.1 - 2.9 7.2 21.7 3 7.2 15.0 1.1 1 0 0 1 1 1 0 Spore coat protein CotO AIF_C PF14721.1 CDI87594.1 - 3 8.1 11.4 3.1 8.0 7.9 1.1 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Draxin PF15550.1 CDI87594.1 - 3.3 7.2 14.9 3.4 7.2 10.3 1.0 1 0 0 1 1 1 0 Draxin PAT1 PF09770.4 CDI87594.1 - 3.5 5.7 28.7 3.3 5.8 19.9 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TraH_2 PF06871.6 CDI87594.1 - 3.5 6.9 6.4 3.9 6.8 4.4 1.1 1 0 0 1 1 1 0 TraH_2 DUF3408 PF11888.3 CDI87594.1 - 3.7 7.4 15.7 4.3 7.2 10.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) RR_TM4-6 PF06459.7 CDI87594.1 - 3.9 7.3 15.3 3.9 7.2 10.6 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 FLO_LFY PF01698.11 CDI87594.1 - 4 6.2 14.7 4.6 5.9 10.2 1.2 1 0 0 1 1 1 0 Floricaula / Leafy protein OATP PF03137.15 CDI87594.1 - 4.1 5.3 12.3 4.3 5.2 8.5 1.0 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Agouti PF05039.7 CDI87594.1 - 4.7 7.6 9.3 5.5 7.3 6.4 1.3 1 0 0 1 1 1 0 Agouti protein NARP1 PF12569.3 CDI87594.1 - 5.1 5.7 16.7 4.7 5.8 11.6 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Suf PF05843.9 CDI87594.1 - 5.3 6.6 20.4 5.5 6.6 14.2 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Glyco_transf_15 PF01793.11 CDI87594.1 - 5.4 5.8 13.1 5.4 5.8 9.1 1.1 1 0 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase Baculo_PP31 PF05311.6 CDI87594.1 - 5.7 6.1 16.1 5.2 6.2 11.2 1.1 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) Gti1_Pac2 PF09729.4 CDI87594.1 - 5.7 6.7 11.2 6.3 6.6 7.7 1.1 1 0 0 1 1 1 0 Gti1/Pac2 family XRN_N PF03159.13 CDI87594.1 - 5.7 6.2 11.9 6.2 6.1 8.2 1.0 1 0 0 1 1 1 0 XRN 5'-3' exonuclease N-terminus EIIBC-GUT_N PF03612.9 CDI87594.1 - 6 6.4 11.4 6 6.4 7.9 1.1 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus DUF4557 PF15101.1 CDI87594.1 - 6.1 6.6 23.7 5.8 6.6 16.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) DUF4512 PF14975.1 CDI87594.1 - 6.6 7.6 8.3 7 7.5 5.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4512) DUF853 PF05872.7 CDI87594.1 - 6.8 4.9 12.1 6.5 4.9 8.4 1.0 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) DDHD PF02862.12 CDI87594.1 - 7.8 6.2 15.0 7.8 6.2 10.4 1.1 1 0 0 1 1 1 0 DDHD domain CPSF100_C PF13299.1 CDI87594.1 - 7.9 6.6 12.8 7.8 6.6 8.9 1.1 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Oleosin PF01277.12 CDI87594.1 - 8.3 6.0 8.5 10 5.7 5.9 1.2 1 0 0 1 1 1 0 Oleosin Neur_chan_memb PF02932.11 CDI87594.1 - 8.3 6.2 12.3 8.1 6.2 8.5 1.0 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region LIM_bind PF01803.11 CDI87594.1 - 8.5 5.4 16.8 8.3 5.4 11.7 1.1 1 0 0 1 1 1 0 LIM-domain binding protein Serinc PF03348.10 CDI87594.1 - 8.6 4.9 13.5 7.9 5.0 9.4 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) Peptidase_U57 PF05582.7 CDI87594.1 - 8.9 5.1 11.6 8.6 5.2 8.0 1.1 1 0 0 1 1 1 0 YabG peptidase U57 Pal1 PF08316.6 CDI87594.1 - 9.2 6.7 8.0 9.6 6.6 5.6 1.2 1 0 0 1 1 1 0 Pal1 cell morphology protein Choline_kinase PF01633.15 CDI87597.1 - 3.3e-25 88.9 0.0 8.4e-20 71.2 0.0 6.5 3 3 3 6 6 6 2 Choline/ethanolamine kinase APH PF01636.18 CDI87597.1 - 6.9e-09 35.7 0.5 6.9e-09 35.7 0.4 5.5 2 2 2 5 5 5 1 Phosphotransferase enzyme family Herpes_DNAp_acc PF04929.7 CDI87597.1 - 0.00051 19.1 4.3 0.00051 19.1 3.0 4.1 2 2 1 3 3 3 1 Herpes DNA replication accessory factor RAB3GAP2_N PF14655.1 CDI87598.1 - 0.0073 15.3 3.9 0.0073 15.3 2.7 2.3 2 1 1 3 3 3 1 Rab3 GTPase-activating protein regulatory subunit N-terminus Spt20 PF12090.3 CDI87598.1 - 0.01 15.2 1.1 0.01 15.2 0.7 2.5 2 1 0 2 2 2 0 Spt20 family SR-25 PF10500.4 CDI87598.1 - 0.05 13.0 28.9 0.04 13.3 3.0 3.5 3 0 0 3 3 3 0 Nuclear RNA-splicing-associated protein Med15 PF09606.5 CDI87598.1 - 1.8 6.6 28.7 0.093 10.9 11.1 2.1 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal Mito_carr PF00153.22 CDI87599.1 - 4.7e-57 189.7 0.5 1.9e-20 72.3 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF3611 PF12263.3 CDI87599.1 - 0.089 12.1 0.2 0.69 9.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3611) SR-25 PF10500.4 CDI87600.1 - 0.0025 17.3 10.4 0.0025 17.3 7.2 8.6 5 3 2 7 7 7 1 Nuclear RNA-splicing-associated protein Utp14 PF04615.8 CDI87601.1 - 0.8 7.8 47.1 0.95 7.5 32.6 1.2 1 0 0 1 1 1 0 Utp14 protein VIT1 PF01988.14 CDI87601.1 - 1.5 8.2 23.5 4.6 6.6 14.4 2.3 1 1 1 2 2 2 0 VIT family Draxin PF15550.1 CDI87601.1 - 1.7 8.1 43.4 2 7.9 30.1 1.0 1 0 0 1 1 1 0 Draxin Caldesmon PF02029.10 CDI87601.1 - 2.5 6.4 31.7 3.4 6.0 22.0 1.3 1 0 0 1 1 1 0 Caldesmon Cellulose_synt PF03552.9 CDI87601.1 - 3 6.0 12.4 3.4 5.8 8.6 1.3 1 0 0 1 1 1 0 Cellulose synthase DUF4045 PF13254.1 CDI87601.1 - 3.2 6.9 41.7 4.6 6.4 28.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) SOBP PF15279.1 CDI87601.1 - 3.7 7.8 41.7 4.8 7.4 28.9 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein CDC45 PF02724.9 CDI87601.1 - 4.9 5.0 31.6 6.6 4.6 21.9 1.3 1 0 0 1 1 1 0 CDC45-like protein Ribosomal_60s PF00428.14 CDI87602.1 - 0.037 14.4 3.2 0.037 14.4 2.2 4.7 2 1 1 3 3 3 0 60s Acidic ribosomal protein Aminotran_5 PF00266.14 CDI87603.1 - 9.5e-16 57.4 1.4 9.5e-16 57.4 1.0 2.1 1 1 1 2 2 2 1 Aminotransferase class-V Dehydrin PF00257.14 CDI87603.1 - 0.23 11.7 1.2 0.37 11.1 0.0 1.8 2 0 0 2 2 2 0 Dehydrin Pollen_allerg_2 PF01620.11 CDI87603.1 - 0.3 11.4 23.8 0.77 10.0 9.6 2.2 2 0 0 2 2 2 0 Ribonuclease (pollen allergen) Med3 PF11593.3 CDI87603.1 - 0.31 10.2 30.7 0.24 10.5 6.0 2.2 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal DUF812 PF05667.6 CDI87603.1 - 1.2 7.5 4.7 1.4 7.3 3.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF812) SR-25 PF10500.4 CDI87603.1 - 1.3 8.4 4.5 2.2 7.7 3.1 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Rubella_E2 PF05749.6 CDI87603.1 - 7.1 5.7 18.3 3.7 6.7 3.9 2.3 2 0 0 2 2 2 0 Rubella membrane glycoprotein E2 Methyltrans_RNA PF04452.9 CDI87604.1 - 3.5e-27 95.0 0.0 1.4e-12 47.2 0.0 2.2 2 0 0 2 2 2 2 RNA methyltransferase DUF2893 PF11459.3 CDI87604.1 - 0.0048 16.6 0.2 0.012 15.3 0.2 1.6 1 0 0 1 1 1 1 Protein of unknwon function (DUF2893) Oligomerisation PF02410.10 CDI87605.1 - 3.6e-09 36.5 0.0 1.2e-08 34.8 0.0 1.9 2 0 0 2 2 2 1 Oligomerisation domain DUF952 PF06108.7 CDI87605.1 - 0.066 13.0 0.0 19 5.1 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF952) PAS_4 PF08448.5 CDI87605.1 - 0.62 10.1 6.0 0.17 11.9 0.7 2.5 1 1 1 2 2 2 0 PAS fold Activator_LAG-3 PF11498.3 CDI87608.1 - 0.00096 18.0 20.9 0.0014 17.4 14.5 1.2 1 0 0 1 1 1 1 Transcriptional activator LAG-3 Suf PF05843.9 CDI87608.1 - 0.089 12.5 2.6 0.1 12.3 1.8 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Collagen PF01391.13 CDI87609.1 - 1.7e-12 46.6 58.4 2.8e-08 33.1 18.2 5.9 6 1 1 7 7 7 2 Collagen triple helix repeat (20 copies) zf-DHHC PF01529.15 CDI87609.1 - 0.032 13.6 0.5 0.69 9.2 0.2 2.6 3 0 0 3 3 3 0 DHHC palmitoyltransferase DUF3360 PF11840.3 CDI87611.1 - 4.7 5.4 8.0 0.4 8.9 2.6 1.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3360) DUF2217 PF10265.4 CDI87613.1 - 0.053 12.2 12.7 0.058 12.1 8.8 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) Nitroreductase PF00881.19 CDI87613.1 - 0.068 12.9 1.1 0.077 12.8 0.4 1.3 1 1 0 1 1 1 0 Nitroreductase family SEFIR PF08357.6 CDI87613.1 - 0.084 12.9 7.3 0.047 13.7 1.6 2.0 2 0 0 2 2 2 0 SEFIR domain DUF3801 PF12687.2 CDI87613.1 - 0.13 11.8 12.5 0.19 11.2 8.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3801) FAM60A PF15396.1 CDI87613.1 - 0.16 11.7 11.1 0.2 11.4 7.7 1.2 1 0 0 1 1 1 0 Protein Family FAM60A Mem_trans PF03547.13 CDI87613.1 - 0.36 9.0 4.3 0.45 8.7 3.0 1.0 1 0 0 1 1 1 0 Membrane transport protein TMEM51 PF15345.1 CDI87613.1 - 0.51 10.0 14.8 0.71 9.5 10.2 1.2 1 0 0 1 1 1 0 Transmembrane protein 51 Mlf1IP PF10248.4 CDI87613.1 - 0.8 9.2 7.8 1 8.9 5.4 1.2 1 0 0 1 1 1 0 Myelodysplasia-myeloid leukemia factor 1-interacting protein SpoIIIAH PF12685.2 CDI87613.1 - 1.2 8.5 10.0 1.8 8.0 6.9 1.3 1 0 0 1 1 1 0 SpoIIIAH-like protein CDK2AP PF09806.4 CDI87613.1 - 1.3 9.2 20.3 1.7 8.8 14.1 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein Pex16 PF08610.5 CDI87613.1 - 1.4 7.8 14.1 1.6 7.6 9.8 1.1 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) WBS_methylT PF12589.3 CDI87613.1 - 1.9 9.0 11.4 7.7 7.0 0.1 2.3 2 0 0 2 2 2 0 Methyltransferase involved in Williams-Beuren syndrome DUF4512 PF14975.1 CDI87613.1 - 2.1 9.2 5.8 6.1 7.7 4.0 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4512) XRN_N PF03159.13 CDI87613.1 - 2.6 7.3 6.1 3.3 7.0 4.3 1.2 1 0 0 1 1 1 0 XRN 5'-3' exonuclease N-terminus FAM70 PF14967.1 CDI87613.1 - 4.1 6.5 6.6 4.8 6.2 4.6 1.1 1 0 0 1 1 1 0 FAM70 protein DUF4642 PF15484.1 CDI87613.1 - 4.7 7.1 9.3 2.1 8.3 4.3 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4642) NPH3 PF03000.9 CDI87613.1 - 4.7 6.6 9.7 5.8 6.3 6.7 1.1 1 0 0 1 1 1 0 NPH3 family Nha1_C PF08619.5 CDI87613.1 - 4.9 6.3 13.1 6 6.0 9.1 1.1 1 0 0 1 1 1 0 Alkali metal cation/H+ antiporter Nha1 C terminus DNA_pol_viral_N PF00242.12 CDI87613.1 - 5.5 5.9 17.4 6.2 5.7 12.0 1.1 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain Lin-8 PF03353.10 CDI87613.1 - 5.6 6.1 13.6 7.1 5.8 9.4 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Spc7_N PF15402.1 CDI87613.1 - 6.3 4.6 15.7 8.6 4.2 10.9 1.2 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 Herpes_DNAp_acc PF04929.7 CDI87613.1 - 6.3 5.6 16.1 7.2 5.4 11.2 1.0 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Utp14 PF04615.8 CDI87613.1 - 6.8 4.7 16.4 8.5 4.4 11.4 1.1 1 0 0 1 1 1 0 Utp14 protein Hid1 PF12722.2 CDI87613.1 - 7 4.1 17.9 8.4 3.9 12.4 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Neur_chan_memb PF02932.11 CDI87613.1 - 8.1 6.2 10.5 10 5.8 7.3 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region FNIP_N PF14636.1 CDI87613.1 - 8.6 6.8 15.5 14 6.1 10.7 1.3 1 0 0 1 1 1 0 Folliculin-interacting protein N-terminus ORC5_C PF14630.1 CDI87613.1 - 9.9 5.5 10.5 12 5.2 7.3 1.3 1 1 0 1 1 1 0 Origin recognition complex (ORC) subunit 5 C-terminus OAD_gamma PF04277.8 CDI87614.1 - 0.58 10.5 5.3 0.7 10.3 3.7 1.1 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain BRF1 PF07741.8 CDI87614.1 - 0.76 10.0 4.7 0.89 9.8 3.3 1.1 1 0 0 1 1 1 0 Brf1-like TBP-binding domain DUF3275 PF11679.3 CDI87614.1 - 1.4 8.4 6.0 1.5 8.4 4.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3275) TraV PF09676.5 CDI87614.1 - 2.2 9.0 6.6 2.6 8.7 4.6 1.0 1 0 0 1 1 1 0 Type IV conjugative transfer system lipoprotein (TraV) DUF2360 PF10152.4 CDI87614.1 - 4.7 7.4 7.9 5.5 7.2 5.5 1.2 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) Nop53 PF07767.6 CDI87615.1 - 0.025 13.5 24.7 0.14 11.1 13.0 2.1 2 0 0 2 2 2 0 Nop53 (60S ribosomal biogenesis) Cwf_Cwc_15 PF04889.7 CDI87615.1 - 0.047 13.4 26.5 0.044 13.4 9.6 2.2 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein CDC45 PF02724.9 CDI87615.1 - 0.15 10.0 31.4 0.057 11.4 2.7 2.1 2 0 0 2 2 2 0 CDC45-like protein Nop14 PF04147.7 CDI87615.1 - 0.49 8.2 25.6 0.79 7.5 3.5 2.1 2 0 0 2 2 2 0 Nop14-like family Isy1 PF06246.7 CDI87615.1 - 1.7 8.0 19.0 0.76 9.1 8.1 2.1 2 0 0 2 2 2 0 Isy1-like splicing family Raftlin PF15250.1 CDI87615.1 - 6.7 5.1 31.4 1.3 7.5 11.0 2.1 2 0 0 2 2 2 0 Raftlin THRAP3_BCLAF1 PF15440.1 CDI87615.1 - 8.4 4.9 35.0 13 4.2 24.3 1.2 1 0 0 1 1 1 0 THRAP3/BCLAF1 family DUF3439 PF11921.3 CDI87616.1 - 0.039 13.7 13.5 0.074 12.7 4.1 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Ni_hydr_CYTB PF01292.15 CDI87616.1 - 1.5 8.2 5.4 0.44 9.9 0.0 2.8 3 1 1 4 4 4 0 Prokaryotic cytochrome b561 RAP1 PF07218.6 CDI87622.1 - 1.7e-05 23.2 3.1 2.4e-05 22.6 2.1 1.1 1 0 0 1 1 1 1 Rhoptry-associated protein 1 (RAP-1) Med15 PF09606.5 CDI87622.1 - 0.059 11.5 27.2 0.092 10.9 18.9 1.3 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal SOBP PF15279.1 CDI87622.1 - 8.2 6.7 16.5 14 5.9 11.5 1.4 1 0 0 1 1 1 0 Sine oculis-binding protein Pex14_N PF04695.8 CDI87624.1 - 0.0034 17.4 8.2 0.0034 17.4 5.7 3.1 2 1 1 3 3 3 1 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF3675 PF12428.3 CDI87624.1 - 0.061 13.5 2.1 0.17 12.1 1.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3675) 60KD_IMP PF02096.15 CDI87624.1 - 0.11 12.0 8.5 0.23 11.0 5.9 1.5 1 0 0 1 1 1 0 60Kd inner membrane protein Peptidase_S49_N PF08496.5 CDI87624.1 - 0.17 11.6 11.2 0.28 10.9 3.7 2.3 2 0 0 2 2 2 0 Peptidase family S49 N-terminal FimP PF09766.4 CDI87624.1 - 0.48 9.4 16.2 0.88 8.5 11.2 1.3 1 0 0 1 1 1 0 Fms-interacting protein DUF4220 PF13968.1 CDI87624.1 - 2 7.4 4.0 4.1 6.4 2.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4220) Suf PF05843.9 CDI87624.1 - 4.4 6.9 15.5 0.094 12.4 4.9 2.1 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) LMBR1 PF04791.11 CDI87624.1 - 6.6 5.1 4.6 9.7 4.6 3.2 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF2203 PF09969.4 CDI87624.1 - 8 6.7 10.2 23 5.2 7.1 1.7 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) LIM_bind PF01803.11 CDI87624.1 - 8.6 5.3 13.0 16 4.4 9.0 1.4 1 0 0 1 1 1 0 LIM-domain binding protein DUF966 PF06136.8 CDI87624.1 - 9.7 5.5 15.4 1.3 8.3 2.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF966) Chorein_N PF12624.2 CDI87625.1 - 8e-06 25.3 0.1 8e-06 25.3 0.0 7.9 10 0 0 10 10 10 1 N-terminal region of Chorein, a TM vesicle-mediated sorter IncA PF04156.9 CDI87625.1 - 0.00071 19.2 11.8 0.00071 19.2 8.2 16.6 10 2 4 15 15 15 4 IncA protein SR-25 PF10500.4 CDI87626.1 - 0.0038 16.7 6.0 0.0038 16.7 4.2 8.6 6 2 1 7 7 7 3 Nuclear RNA-splicing-associated protein DUF3801 PF12687.2 CDI87626.1 - 0.069 12.7 26.8 0.057 12.9 0.2 3.0 3 1 0 3 3 3 0 Protein of unknown function (DUF3801) Ycf1 PF05758.7 CDI87627.1 - 0.00095 17.0 14.4 0.00095 17.0 10.0 2.2 2 0 0 2 2 2 1 Ycf1 SR-25 PF10500.4 CDI87627.1 - 0.0027 17.2 9.9 0.0027 17.2 6.9 6.7 4 2 1 6 6 6 2 Nuclear RNA-splicing-associated protein PBP1_TM PF14812.1 CDI87628.1 - 0.84 9.9 17.4 0.37 11.1 3.2 2.2 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF4484 PF14831.1 CDI87628.1 - 0.86 9.6 18.9 1 9.4 13.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4484) XAP5 PF04921.9 CDI87628.1 - 0.91 9.0 24.4 1.1 8.7 16.9 1.1 1 0 0 1 1 1 0 XAP5, circadian clock regulator Gti1_Pac2 PF09729.4 CDI87628.1 - 3.1 7.6 25.2 0.049 13.4 3.0 2.0 2 0 0 2 2 2 0 Gti1/Pac2 family 7tm_1 PF00001.16 CDI87628.1 - 6.1 5.8 13.5 10 5.1 9.3 1.4 1 1 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) SID-1_RNA_chan PF13965.1 CDI87628.1 - 6.7 4.7 15.7 8.3 4.4 10.9 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 PAT1 PF09770.4 CDI87628.1 - 7.3 4.6 57.3 7.6 4.6 39.7 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Peptidase_M56 PF05569.6 CDI87628.1 - 8.8 5.1 14.8 11 4.9 10.3 1.1 1 0 0 1 1 1 0 BlaR1 peptidase M56 BAF1_ABF1 PF04684.8 CDI87630.1 - 0.00085 18.2 15.9 0.00085 18.2 11.0 4.5 3 2 0 3 3 3 1 BAF1 / ABF1 chromatin reorganising factor SseC PF04888.7 CDI87630.1 - 0.0014 18.0 24.1 0.0014 18.0 16.7 2.9 2 1 0 2 2 2 1 Secretion system effector C (SseC) like family TAP42 PF04177.7 CDI87630.1 - 0.0053 15.7 5.1 0.0066 15.4 3.6 1.2 1 0 0 1 1 1 1 TAP42-like family Dynamin_N PF00350.18 CDI87630.1 - 0.056 13.2 2.0 0.1 12.3 1.4 1.4 1 0 0 1 1 1 0 Dynamin family FimP PF09766.4 CDI87630.1 - 0.14 11.1 8.1 0.22 10.5 5.6 1.2 1 0 0 1 1 1 0 Fms-interacting protein DUF3371 PF11851.3 CDI87630.1 - 0.15 12.7 9.3 0.14 12.8 5.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3371) Activator_LAG-3 PF11498.3 CDI87630.1 - 5.3 5.6 25.3 10 4.6 17.5 1.4 1 0 0 1 1 1 0 Transcriptional activator LAG-3 SR-25 PF10500.4 CDI87632.1 - 2.3e-07 30.5 9.1 2.4e-07 30.4 6.3 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Pex14_N PF04695.8 CDI87632.1 - 0.0027 17.7 11.0 0.0038 17.2 7.7 1.3 1 0 0 1 1 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF4614 PF15391.1 CDI87632.1 - 0.014 15.1 7.5 0.016 14.9 5.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) CDC45 PF02724.9 CDI87632.1 - 0.018 13.1 6.2 0.02 12.9 4.3 1.1 1 0 0 1 1 1 0 CDC45-like protein CTNNB1_binding PF08347.6 CDI87632.1 - 0.019 15.2 5.0 0.023 14.9 3.5 1.1 1 0 0 1 1 1 0 N-terminal CTNNB1 binding DUF3619 PF12279.3 CDI87632.1 - 0.022 14.8 3.2 0.028 14.5 2.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3619) SPX PF03105.14 CDI87632.1 - 0.046 13.5 4.6 0.042 13.6 3.2 1.1 1 0 0 1 1 1 0 SPX domain Bul1_N PF04425.7 CDI87632.1 - 0.048 12.2 2.8 0.043 12.3 1.9 1.1 1 0 0 1 1 1 0 Bul1 N terminus MM_CoA_mutase PF01642.17 CDI87632.1 - 0.052 11.6 1.0 0.063 11.4 0.7 1.0 1 0 0 1 1 1 0 Methylmalonyl-CoA mutase PPP4R2 PF09184.6 CDI87632.1 - 0.068 12.7 4.9 0.065 12.7 3.4 1.2 1 0 0 1 1 1 0 PPP4R2 Spc7_N PF15402.1 CDI87632.1 - 0.13 10.2 9.2 0.12 10.3 6.4 1.0 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 DUF4175 PF13779.1 CDI87632.1 - 0.13 9.9 16.9 0.14 9.8 11.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) F-protein PF00469.15 CDI87632.1 - 0.14 11.5 2.5 0.14 11.5 1.8 1.2 1 0 0 1 1 1 0 Negative factor, (F-Protein) or Nef DUF605 PF04652.11 CDI87632.1 - 0.17 11.2 9.5 0.19 11.1 6.6 1.0 1 0 0 1 1 1 0 Vta1 like BRF1 PF07741.8 CDI87632.1 - 0.19 11.9 6.4 0.26 11.5 4.4 1.3 1 0 0 1 1 1 0 Brf1-like TBP-binding domain DUF3464 PF11947.3 CDI87632.1 - 0.27 10.7 3.5 0.33 10.3 2.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) DUF2076 PF09849.4 CDI87632.1 - 0.31 11.0 17.0 0.39 10.7 11.8 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) DDHD PF02862.12 CDI87632.1 - 0.34 10.6 8.7 0.36 10.5 6.0 1.1 1 0 0 1 1 1 0 DDHD domain DUF883 PF05957.8 CDI87632.1 - 0.35 11.2 7.5 0.49 10.8 5.2 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) Dsh_C PF12316.3 CDI87632.1 - 0.38 10.8 10.1 0.41 10.7 7.0 1.2 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal Kei1 PF08552.6 CDI87632.1 - 0.71 9.4 3.3 0.75 9.4 2.3 1.3 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 Macoilin PF09726.4 CDI87632.1 - 0.8 7.9 8.6 0.92 7.7 6.0 1.1 1 0 0 1 1 1 0 Transmembrane protein DUF4407 PF14362.1 CDI87632.1 - 0.97 8.3 7.3 1.2 8.0 5.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Sporozoite_P67 PF05642.6 CDI87632.1 - 1.1 7.0 5.1 1.3 6.8 3.6 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Suf PF05843.9 CDI87632.1 - 1.3 8.6 11.6 1.5 8.4 8.1 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) TFIIA PF03153.8 CDI87632.1 - 1.3 8.7 15.1 1.8 8.3 10.4 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SKIP_SNW PF02731.10 CDI87632.1 - 1.6 8.2 11.2 0.89 9.0 6.2 1.6 2 0 0 2 2 2 0 SKIP/SNW domain EIIBC-GUT_N PF03612.9 CDI87632.1 - 1.7 8.2 4.2 2.1 7.9 2.9 1.2 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Strabismus PF06638.6 CDI87632.1 - 1.9 6.7 5.3 2.2 6.5 3.7 1.0 1 0 0 1 1 1 0 Strabismus protein DUF2201_N PF13203.1 CDI87632.1 - 2 7.5 11.4 2.3 7.3 7.9 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain ABA_WDS PF02496.11 CDI87632.1 - 2.2 8.4 6.3 10 6.3 0.3 2.6 2 1 0 2 2 2 0 ABA/WDS induced protein DUF3043 PF11241.3 CDI87632.1 - 3.3 7.2 5.5 4.1 6.9 3.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) Raftlin PF15250.1 CDI87632.1 - 3.4 6.0 8.5 3.8 5.9 5.9 1.0 1 0 0 1 1 1 0 Raftlin DUF3138 PF11336.3 CDI87632.1 - 4 5.5 10.0 4.4 5.3 6.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) DUF2146 PF10220.4 CDI87632.1 - 4.4 5.1 8.5 4.7 5.0 5.9 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2146) Band_3_cyto PF07565.8 CDI87632.1 - 4.8 6.6 9.2 5.5 6.4 6.4 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain ETRAMP PF09716.5 CDI87632.1 - 6.6 6.7 7.9 7.9 6.5 1.6 2.3 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) DUF4557 PF15101.1 CDI87632.1 - 6.9 6.4 14.3 8.6 6.1 9.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) Chorion_2 PF03964.10 CDI87632.1 - 7.1 7.2 20.8 9.7 6.8 2.3 2.2 1 1 1 2 2 2 0 Chorion family 2 TEX19 PF15553.1 CDI87632.1 - 7.9 6.3 8.7 7.3 6.4 3.4 2.1 2 0 0 2 2 2 0 Testis-expressed protein 19 Gti1_Pac2 PF09729.4 CDI87632.1 - 8.6 6.2 8.5 10 5.9 5.9 1.1 1 0 0 1 1 1 0 Gti1/Pac2 family Shisa PF13908.1 CDI87632.1 - 8.8 6.4 13.3 12 6.0 9.2 1.1 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Activator_LAG-3 PF11498.3 CDI87632.1 - 8.9 4.9 26.8 11 4.5 18.6 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 RR_TM4-6 PF06459.7 CDI87632.1 - 9.6 6.0 10.3 14 5.4 7.1 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SR-25 PF10500.4 CDI87634.1 - 0.0025 17.3 24.7 0.0037 16.7 17.1 1.3 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein DUF605 PF04652.11 CDI87634.1 - 0.006 16.0 20.1 0.0073 15.7 14.0 1.1 1 0 0 1 1 1 1 Vta1 like SprA-related PF12118.3 CDI87634.1 - 0.036 13.4 32.7 0.047 13.0 22.7 1.1 1 0 0 1 1 1 0 SprA-related family Suf PF05843.9 CDI87634.1 - 0.11 12.1 24.6 0.2 11.3 17.2 1.4 1 1 0 1 1 1 0 Suppressor of forked protein (Suf) DUF966 PF06136.8 CDI87634.1 - 0.12 11.8 17.9 0.14 11.5 12.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF966) OmpH PF03938.9 CDI87634.1 - 0.24 11.3 19.0 0.35 10.8 13.1 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) SOBP PF15279.1 CDI87634.1 - 0.29 11.4 14.7 0.35 11.2 10.2 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein DUF2413 PF10310.4 CDI87634.1 - 0.38 9.5 26.0 0.56 8.9 18.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) Daxx PF03344.10 CDI87634.1 - 0.39 9.1 24.8 0.43 8.9 17.2 1.1 1 0 0 1 1 1 0 Daxx Family RR_TM4-6 PF06459.7 CDI87634.1 - 0.43 10.4 23.8 0.6 9.9 16.5 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Nop14 PF04147.7 CDI87634.1 - 0.62 7.9 26.7 0.79 7.5 18.5 1.0 1 0 0 1 1 1 0 Nop14-like family Macoilin PF09726.4 CDI87634.1 - 1.6 6.8 16.9 2 6.6 11.7 1.2 1 0 0 1 1 1 0 Transmembrane protein FLO_LFY PF01698.11 CDI87634.1 - 2 7.1 14.7 3 6.6 10.2 1.4 1 0 0 1 1 1 0 Floricaula / Leafy protein AvrE PF11725.3 CDI87634.1 - 2.7 4.9 21.2 2.8 4.8 14.7 1.0 1 0 0 1 1 1 0 Pathogenicity factor Adeno_hexon PF01065.14 CDI87634.1 - 3.1 6.5 9.5 3.9 6.2 6.6 1.1 1 0 0 1 1 1 0 Hexon, adenovirus major coat protein, N-terminal domain Hid1 PF12722.2 CDI87634.1 - 3.2 5.3 21.6 3.6 5.1 15.0 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Presenilin PF01080.12 CDI87634.1 - 3.2 6.4 13.9 4 6.1 9.6 1.4 1 0 0 1 1 1 0 Presenilin SAPS PF04499.10 CDI87634.1 - 4.4 5.8 18.2 5.4 5.5 12.6 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Ebola_NP PF05505.7 CDI87634.1 - 7.2 4.5 19.5 7.8 4.4 13.5 1.1 1 0 0 1 1 1 0 Ebola nucleoprotein Ribosomal_60s PF00428.14 CDI87635.1 - 0.57 10.6 6.9 1 9.7 4.8 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein DUF4544 PF15077.1 CDI87635.1 - 6.6 6.1 13.5 7.9 5.9 9.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4544) CDC45 PF02724.9 CDI87635.1 - 8 4.3 20.0 8.2 4.3 13.8 1.2 1 0 0 1 1 1 0 CDC45-like protein SR-25 PF10500.4 CDI87636.1 - 2.1e-06 27.3 29.5 2.1e-06 27.3 20.5 2.5 2 1 0 2 2 2 1 Nuclear RNA-splicing-associated protein LMBR1 PF04791.11 CDI87636.1 - 3.3 6.1 12.6 26 3.2 8.7 2.1 1 1 0 1 1 1 0 LMBR1-like membrane protein TPR_2 PF07719.12 CDI87637.1 - 1.6e-06 27.5 35.4 3.4e-05 23.4 0.2 8.7 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_11 PF13414.1 CDI87637.1 - 1.4e-05 24.6 39.5 0.0055 16.3 1.0 6.9 7 1 0 7 7 7 4 TPR repeat MIP-T3 PF10243.4 CDI87637.1 - 7.1e-05 21.4 38.7 0.00031 19.3 12.9 4.1 5 1 0 5 5 5 2 Microtubule-binding protein MIP-T3 TPR_1 PF00515.23 CDI87637.1 - 0.00023 20.6 15.3 0.00055 19.4 0.1 6.2 7 0 0 7 7 7 1 Tetratricopeptide repeat Med15 PF09606.5 CDI87637.1 - 0.00093 17.5 26.2 0.00093 17.5 18.2 4.9 3 1 0 4 4 4 2 ARC105 or Med15 subunit of Mediator complex non-fungal TPR_16 PF13432.1 CDI87637.1 - 0.003 18.1 0.1 0.003 18.1 0.1 12.0 11 2 2 13 13 13 4 Tetratricopeptide repeat TPR_8 PF13181.1 CDI87637.1 - 0.0037 16.9 0.1 0.091 12.5 0.0 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat Phostensin_N PF13916.1 CDI87637.1 - 0.013 15.4 0.7 0.013 15.4 0.5 10.0 6 3 3 9 9 9 0 PP1-regulatory protein, Phostensin N-terminal TPR_6 PF13174.1 CDI87637.1 - 0.26 11.8 29.8 0.93 10.0 0.4 9.2 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_17 PF13431.1 CDI87637.1 - 0.28 11.4 9.7 19 5.7 0.0 6.3 5 0 0 5 5 5 0 Tetratricopeptide repeat Asparaginase PF00710.15 CDI87638.1 - 7.2e-08 31.6 0.1 3e-07 29.6 0.0 2.1 2 0 0 2 2 2 1 Asparaginase Med15 PF09606.5 CDI87638.1 - 0.00019 19.8 82.0 0.00026 19.3 56.8 1.1 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal TT_ORF1 PF02956.9 CDI87638.1 - 0.53 8.6 12.9 1.9 6.8 4.3 2.1 2 0 0 2 2 2 0 TT viral orf 1 Ycf1 PF05758.7 CDI87638.1 - 1.9 6.0 15.8 1.2 6.7 3.2 2.1 2 0 0 2 2 2 0 Ycf1 BAF1_ABF1 PF04684.8 CDI87638.1 - 7.2 5.3 60.0 2.3 6.9 18.0 2.4 2 1 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor Trypan_PARP PF05887.6 CDI87639.1 - 0.00054 19.7 1.8 0.00054 19.7 1.2 2.4 2 1 0 2 2 2 1 Procyclic acidic repetitive protein (PARP) Yip1 PF04893.12 CDI87639.1 - 0.07 12.6 0.4 2.5 7.5 0.8 2.1 1 1 1 2 2 2 0 Yip1 domain DUF3439 PF11921.3 CDI87639.1 - 0.61 9.8 4.4 1.6 8.4 3.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) RAP1 PF07218.6 CDI87639.1 - 6.6 4.6 12.1 8.5 4.3 8.4 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) vMSA PF00695.14 CDI87640.1 - 2.3 7.3 6.1 0.66 9.1 1.3 2.1 2 0 0 2 2 2 0 Major surface antigen from hepadnavirus Dehydrin PF00257.14 CDI87640.1 - 4.9 7.4 16.7 17 5.7 0.0 4.3 4 0 0 4 4 4 0 Dehydrin Macoilin PF09726.4 CDI87640.1 - 9.8 4.3 20.6 15 3.6 14.3 1.4 1 0 0 1 1 1 0 Transmembrane protein Kinesin PF00225.18 CDI87641.1 - 1.5e-19 69.9 0.1 1.5e-19 69.9 0.1 3.2 1 1 1 2 2 2 1 Kinesin motor domain Spt20 PF12090.3 CDI87641.1 - 0.46 9.8 16.9 0.11 11.8 1.4 2.6 2 0 0 2 2 2 0 Spt20 family eIF-3_zeta PF05091.7 CDI87641.1 - 9 4.7 15.7 15 4.0 10.9 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) BAF1_ABF1 PF04684.8 CDI87642.1 - 0.0012 17.8 19.8 0.0012 17.8 13.7 12.3 3 1 5 10 10 10 2 BAF1 / ABF1 chromatin reorganising factor RAB3GAP2_N PF14655.1 CDI87642.1 - 0.0034 16.4 4.5 0.0034 16.4 3.1 9.9 3 2 4 8 8 8 1 Rab3 GTPase-activating protein regulatory subunit N-terminus SpoOE-like PF09388.5 CDI87643.1 - 0.001 18.5 1.3 1 8.9 0.0 2.6 2 0 0 2 2 2 2 Spo0E like sporulation regulatory protein Apolipoprotein PF01442.13 CDI87643.1 - 0.041 13.3 0.2 0.082 12.4 0.2 1.5 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain DUF1664 PF07889.7 CDI87643.1 - 0.17 11.6 0.7 2.7 7.7 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF4635 PF15466.1 CDI87643.1 - 1.2 8.4 5.9 2.1 7.6 0.4 2.8 1 1 2 3 3 3 0 Domain of unknown function (DUF4635) 5_3_exonuc PF01367.15 CDI87645.1 - 3.3e-07 30.4 0.0 3.3e-07 30.4 0.0 3.9 5 0 0 5 5 5 1 5'-3' exonuclease, C-terminal SAM fold SAPS PF04499.10 CDI87645.1 - 1.6 7.2 0.0 1.6 7.2 0.0 5.1 4 2 0 4 4 4 0 SIT4 phosphatase-associated protein LRR_9 PF14580.1 CDI87646.1 - 1.2e-28 99.8 1.0 1.6e-28 99.4 0.1 1.6 2 0 0 2 2 1 1 Leucine-rich repeat LRR_8 PF13855.1 CDI87646.1 - 3.5e-05 23.4 2.3 8.4e-05 22.2 1.6 1.6 1 0 0 1 1 1 1 Leucine rich repeat Med15 PF09606.5 CDI87646.1 - 3.7e-05 22.1 44.9 4e-05 22.0 31.1 1.2 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal LRR_4 PF12799.2 CDI87646.1 - 5e-05 22.8 8.5 0.0005 19.6 2.3 2.6 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) U79_P34 PF03064.11 CDI87646.1 - 7.4e-05 22.3 6.3 0.00013 21.6 4.4 1.3 1 0 0 1 1 1 1 HSV U79 / HCMV P34 PAT1 PF09770.4 CDI87646.1 - 0.00049 18.5 35.4 0.00056 18.2 24.5 1.1 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 Ycf1 PF05758.7 CDI87646.1 - 0.0073 14.0 13.0 0.0077 14.0 9.0 1.2 1 0 0 1 1 1 1 Ycf1 Dicty_REP PF05086.7 CDI87646.1 - 0.0073 14.1 9.1 0.0092 13.8 6.3 1.1 1 0 0 1 1 1 1 Dictyostelium (Slime Mold) REP protein SAGA-Tad1 PF12767.2 CDI87646.1 - 0.018 14.7 20.3 0.024 14.2 14.0 1.2 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit GAGA_bind PF06217.7 CDI87646.1 - 0.021 14.8 11.0 0.028 14.3 7.6 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family Band_3_cyto PF07565.8 CDI87646.1 - 0.027 13.9 11.9 0.039 13.4 8.3 1.4 1 0 0 1 1 1 0 Band 3 cytoplasmic domain eIF-3_zeta PF05091.7 CDI87646.1 - 0.042 12.4 20.1 0.054 12.1 13.9 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) FAM60A PF15396.1 CDI87646.1 - 0.093 12.4 11.3 0.12 12.1 7.9 1.3 1 0 0 1 1 1 0 Protein Family FAM60A LicD PF04991.8 CDI87646.1 - 0.1 12.6 0.6 0.13 12.3 0.4 1.2 1 0 0 1 1 1 0 LicD family Zip PF02535.17 CDI87646.1 - 0.11 11.4 2.6 0.14 11.1 1.8 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter NPR3 PF03666.8 CDI87646.1 - 0.15 10.5 14.5 0.23 9.9 10.0 1.3 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Ribosomal_60s PF00428.14 CDI87646.1 - 0.2 12.0 23.2 1.6 9.1 0.2 2.5 2 0 0 2 2 2 0 60s Acidic ribosomal protein Raftlin PF15250.1 CDI87646.1 - 0.21 10.0 16.2 0.3 9.5 11.2 1.2 1 0 0 1 1 1 0 Raftlin Activator_LAG-3 PF11498.3 CDI87646.1 - 0.25 10.0 61.5 0.32 9.6 42.6 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 HCO3_cotransp PF00955.16 CDI87646.1 - 0.3 9.7 3.7 0.37 9.4 2.6 1.1 1 0 0 1 1 1 0 HCO3- transporter family Parvo_coat PF00740.13 CDI87646.1 - 0.31 9.9 18.0 0.38 9.6 12.5 1.1 1 0 0 1 1 1 0 Parvovirus coat protein VP2 LRR_1 PF00560.28 CDI87646.1 - 0.34 11.1 4.9 24 5.4 0.1 3.6 3 0 0 3 3 3 0 Leucine Rich Repeat Borrelia_P83 PF05262.6 CDI87646.1 - 0.44 8.7 25.7 0.58 8.3 17.8 1.3 1 0 0 1 1 1 0 Borrelia P83/100 protein Bul1_N PF04425.7 CDI87646.1 - 0.47 8.9 12.4 0.68 8.4 8.6 1.3 1 0 0 1 1 1 0 Bul1 N terminus DUF4175 PF13779.1 CDI87646.1 - 0.48 8.0 59.5 0.54 7.8 41.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Anoctamin PF04547.7 CDI87646.1 - 0.57 8.7 6.5 0.63 8.6 4.5 1.2 1 0 0 1 1 1 0 Calcium-activated chloride channel Ndc1_Nup PF09531.5 CDI87646.1 - 0.61 8.4 11.2 0.72 8.1 7.8 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Neur_chan_memb PF02932.11 CDI87646.1 - 1 9.1 11.0 1.4 8.7 7.6 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region PBP1_TM PF14812.1 CDI87646.1 - 1.4 9.2 11.5 3 8.2 8.0 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Presenilin PF01080.12 CDI87646.1 - 1.5 7.5 13.3 2.4 6.9 9.2 1.3 1 0 0 1 1 1 0 Presenilin Cellulose_synt PF03552.9 CDI87646.1 - 1.6 6.9 7.7 2 6.6 5.4 1.1 1 0 0 1 1 1 0 Cellulose synthase RNA_pol_Rpb1_5 PF04998.12 CDI87646.1 - 2.8 7.1 15.8 2.6 7.2 9.8 1.7 2 0 0 2 2 2 0 RNA polymerase Rpb1, domain 5 SpoVR PF04293.8 CDI87646.1 - 2.9 6.1 20.6 4.2 5.6 14.3 1.2 1 0 0 1 1 1 0 SpoVR like protein Mgr1 PF08602.5 CDI87646.1 - 3.7 6.4 10.1 5.4 5.9 7.0 1.3 1 0 0 1 1 1 0 Mgr1-like, i-AAA protease complex subunit MAT1 PF06391.8 CDI87646.1 - 4 6.9 28.9 8.3 5.9 20.1 1.5 1 0 0 1 1 1 0 CDK-activating kinase assembly factor MAT1 Macoilin PF09726.4 CDI87646.1 - 4 5.5 23.4 5.2 5.2 16.2 1.1 1 0 0 1 1 1 0 Transmembrane protein Peroxin-13_N PF04088.8 CDI87646.1 - 4.1 7.3 11.6 0.55 10.1 4.8 1.9 2 0 0 2 2 2 0 Peroxin 13, N-terminal region G-7-MTase PF12803.2 CDI87646.1 - 5.3 6.0 11.5 8 5.4 8.0 1.2 1 0 0 1 1 1 0 mRNA (guanine-7-)methyltransferase (G-7-MTase) Maf1 PF09174.5 CDI87646.1 - 5.3 6.8 10.7 8.9 6.1 7.4 1.4 1 0 0 1 1 1 0 Maf1 regulator Ctr PF04145.10 CDI87646.1 - 5.8 6.9 12.2 11 6.0 8.5 1.6 1 0 0 1 1 1 0 Ctr copper transporter family DUF4220 PF13968.1 CDI87646.1 - 6.1 5.8 9.1 7.9 5.4 6.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4220) Glyco_transf_15 PF01793.11 CDI87646.1 - 6.7 5.5 18.9 11 4.7 13.1 1.4 1 0 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase V_ATPase_I PF01496.14 CDI87646.1 - 7.9 4.2 13.1 8.8 4.0 9.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Folate_carrier PF01770.13 CDI87646.1 - 9.9 4.5 14.2 14 4.0 9.9 1.2 1 0 0 1 1 1 0 Reduced folate carrier FA_desaturase PF00487.19 CDI87647.1 - 0.4 10.0 0.8 1.2 8.4 0.5 1.8 1 0 0 1 1 1 0 Fatty acid desaturase SPX PF03105.14 CDI87649.1 - 2.5e-07 30.7 4.9 2.5e-07 30.7 3.4 7.3 2 2 2 4 4 4 1 SPX domain Med15 PF09606.5 CDI87649.1 - 6.4e-05 21.3 78.4 6.4e-05 21.3 54.4 3.7 3 1 0 3 3 3 2 ARC105 or Med15 subunit of Mediator complex non-fungal Cwf_Cwc_15 PF04889.7 CDI87650.1 - 0.0011 18.7 0.3 0.0015 18.3 0.2 1.3 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein DUF3801 PF12687.2 CDI87650.1 - 0.0038 16.8 1.2 0.0038 16.8 0.8 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3801) SR-25 PF10500.4 CDI87650.1 - 0.081 12.3 31.6 0.016 14.6 14.5 2.5 2 1 0 2 2 2 0 Nuclear RNA-splicing-associated protein Nucleo_P87 PF07267.6 CDI87650.1 - 0.85 8.2 8.9 1.2 7.7 6.1 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Dehydrin PF00257.14 CDI87650.1 - 3.7 7.8 16.1 0.34 11.2 0.4 3.1 2 1 0 2 2 2 0 Dehydrin Radical_SAM PF04055.16 CDI87652.1 - 0.084 13.0 0.5 0.9 9.6 0.0 2.4 3 0 0 3 3 3 0 Radical SAM superfamily IncA PF04156.9 CDI87653.1 - 0.01 15.4 8.1 0.01 15.4 5.6 2.3 2 0 0 2 2 2 0 IncA protein AAA_23 PF13476.1 CDI87653.1 - 0.04 14.2 41.7 0.12 12.6 2.7 2.1 2 0 0 2 2 2 0 AAA domain RNA_pol_Rpb1_5 PF04998.12 CDI87653.1 - 0.19 10.9 16.4 3.8 6.6 8.5 2.1 2 0 0 2 2 2 0 RNA polymerase Rpb1, domain 5 Hamartin PF04388.7 CDI87653.1 - 0.2 10.3 32.9 0.23 10.0 22.8 1.0 1 0 0 1 1 1 0 Hamartin protein PBP1_TM PF14812.1 CDI87653.1 - 0.57 10.5 15.4 0.64 10.3 4.6 2.4 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CDC27 PF09507.5 CDI87653.1 - 5.7 6.0 40.4 8.3 5.5 28.0 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 TFIIA PF03153.8 CDI87653.1 - 7.6 6.3 72.9 12 5.6 50.5 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Parvo_coat PF00740.13 CDI87653.1 - 8.1 5.2 41.2 10 4.9 28.5 1.1 1 0 0 1 1 1 0 Parvovirus coat protein VP2 Dala_Dala_lig_N PF01820.16 CDI87653.1 - 9.8 6.5 20.2 6.5 7.1 7.3 2.5 2 0 0 2 2 2 0 D-ala D-ala ligase N-terminus MIP-T3 PF10243.4 CDI87655.1 - 0.0019 16.7 58.3 0.0025 16.3 40.4 1.0 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 DUF605 PF04652.11 CDI87655.1 - 0.78 9.0 30.3 0.94 8.8 21.0 1.0 1 0 0 1 1 1 0 Vta1 like ABC2_membrane_3 PF12698.2 CDI87655.1 - 1.2 8.0 2.6 1.3 7.9 1.8 1.0 1 0 0 1 1 1 0 ABC-2 family transporter protein AAA_23 PF13476.1 CDI87655.1 - 3.2 8.0 30.3 5.6 7.2 21.0 1.4 1 0 0 1 1 1 0 AAA domain ALMT PF11744.3 CDI87657.1 - 0.29 9.7 1.6 0.31 9.6 1.1 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Syntaxin-6_N PF09177.6 CDI87657.1 - 0.65 10.4 3.6 0.92 9.9 1.8 1.8 2 1 0 2 2 2 0 Syntaxin 6, N-terminal APG6 PF04111.7 CDI87657.1 - 2.6 7.0 7.7 3.5 6.5 5.3 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF1510 PF07423.6 CDI87658.1 - 0.00019 20.8 6.4 0.0002 20.8 4.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) TRAP_alpha PF03896.11 CDI87658.1 - 0.0093 14.9 1.9 0.0097 14.9 1.3 1.0 1 0 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit RIC3 PF15361.1 CDI87658.1 - 0.011 16.0 8.2 0.011 15.9 5.7 1.0 1 0 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 Cytochrom_B_N PF00033.14 CDI87658.1 - 0.021 14.1 0.1 0.024 13.9 0.1 1.1 1 0 0 1 1 1 0 Cytochrome b(N-terminal)/b6/petB OAD_gamma PF04277.8 CDI87658.1 - 0.022 15.1 2.5 0.14 12.5 1.7 1.9 1 1 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain Zip PF02535.17 CDI87658.1 - 0.028 13.4 8.7 0.026 13.5 6.1 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Ycf1 PF05758.7 CDI87658.1 - 0.14 9.8 8.6 0.13 9.9 6.0 1.0 1 0 0 1 1 1 0 Ycf1 Serinc PF03348.10 CDI87658.1 - 0.16 10.6 8.1 0.17 10.5 5.6 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) Bap31 PF05529.7 CDI87658.1 - 0.16 11.3 8.7 0.21 11.0 6.0 1.2 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like DUF1980 PF09323.5 CDI87658.1 - 0.2 11.3 5.1 0.21 11.3 3.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) DUF4220 PF13968.1 CDI87658.1 - 0.22 10.5 3.7 0.21 10.6 2.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4220) NicO PF03824.11 CDI87658.1 - 0.29 10.4 1.4 0.31 10.3 1.0 1.1 1 0 0 1 1 1 0 High-affinity nickel-transport protein Gastrin PF00918.12 CDI87658.1 - 0.33 11.7 13.6 0.41 11.4 9.5 1.1 1 0 0 1 1 1 0 Gastrin/cholecystokinin family Shisa PF13908.1 CDI87658.1 - 0.4 10.8 13.2 0.39 10.8 9.2 1.0 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator DUF3381 PF11861.3 CDI87658.1 - 0.41 10.1 12.1 0.44 10.0 8.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) Peptidase_S49_N PF08496.5 CDI87658.1 - 0.47 10.2 8.4 0.48 10.2 5.8 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal SID-1_RNA_chan PF13965.1 CDI87658.1 - 0.55 8.3 5.1 0.55 8.3 3.6 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Hid1 PF12722.2 CDI87658.1 - 0.6 7.7 13.0 0.58 7.7 9.0 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein YqfQ PF14181.1 CDI87658.1 - 0.66 9.9 16.0 0.73 9.8 11.1 1.0 1 0 0 1 1 1 0 YqfQ-like protein RP-C_C PF11800.3 CDI87658.1 - 0.73 9.5 11.9 0.72 9.5 8.3 1.0 1 0 0 1 1 1 0 Replication protein C C-terminal region Pex16 PF08610.5 CDI87658.1 - 0.74 8.7 10.3 1.1 8.1 7.1 1.3 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) Neur_chan_memb PF02932.11 CDI87658.1 - 1 9.2 6.7 1 9.2 4.6 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF3450 PF11932.3 CDI87658.1 - 1 8.5 22.4 1.1 8.5 15.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF4446 PF14584.1 CDI87658.1 - 1.1 9.0 6.1 1.2 8.9 4.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) R_equi_Vir PF05526.6 CDI87658.1 - 1.3 8.6 5.9 1.3 8.6 4.1 1.1 1 0 0 1 1 1 0 Rhodococcus equi virulence-associated protein DUF2370 PF10176.4 CDI87658.1 - 1.3 8.2 7.4 1.4 8.2 5.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) Folate_carrier PF01770.13 CDI87658.1 - 1.4 7.3 5.7 1.3 7.4 3.9 1.1 1 0 0 1 1 1 0 Reduced folate carrier Endonuc_Holl PF10107.4 CDI87658.1 - 2 8.0 10.4 2.2 7.9 7.2 1.1 1 0 0 1 1 1 0 Endonuclease related to archaeal Holliday junction resolvase Peroxin-13_N PF04088.8 CDI87658.1 - 2.1 8.3 4.8 2.2 8.2 3.3 1.3 1 0 0 1 1 1 0 Peroxin 13, N-terminal region OATP PF03137.15 CDI87658.1 - 2.1 6.3 8.7 1.9 6.4 6.0 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Mem_trans PF03547.13 CDI87658.1 - 2.2 6.4 4.6 2.1 6.5 3.2 1.1 1 0 0 1 1 1 0 Membrane transport protein TFIIA PF03153.8 CDI87658.1 - 2.3 8.0 26.2 2.6 7.8 18.2 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit FAM60A PF15396.1 CDI87658.1 - 2.3 7.8 10.4 2.4 7.8 7.2 1.0 1 0 0 1 1 1 0 Protein Family FAM60A DUF2782 PF11191.3 CDI87658.1 - 3.4 7.6 9.9 14 5.7 6.9 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2782) DUF3260 PF11658.3 CDI87658.1 - 3.5 5.6 11.7 3.6 5.6 8.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3260) FAM176 PF14851.1 CDI87658.1 - 4.1 7.0 9.9 6.9 6.3 6.9 1.4 1 1 0 1 1 1 0 FAM176 family Band_3_cyto PF07565.8 CDI87658.1 - 5.1 6.5 13.5 5.1 6.5 9.3 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain DDHD PF02862.12 CDI87658.1 - 5.5 6.7 13.7 5.7 6.6 9.5 1.0 1 0 0 1 1 1 0 DDHD domain Ctr PF04145.10 CDI87658.1 - 5.8 6.9 8.5 8.2 6.4 5.9 1.3 1 1 0 1 1 1 0 Ctr copper transporter family TCP PF03634.8 CDI87658.1 - 6.6 7.1 17.8 7.9 6.8 12.3 1.1 1 0 0 1 1 1 0 TCP family transcription factor DUF3959 PF13105.1 CDI87658.1 - 7.1 5.8 6.1 6.6 5.9 4.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3959) Gti1_Pac2 PF09729.4 CDI87658.1 - 7.2 6.4 10.5 7.3 6.4 7.3 1.1 1 0 0 1 1 1 0 Gti1/Pac2 family AIF_C PF14721.1 CDI87658.1 - 7.2 6.8 13.7 7.9 6.7 9.5 1.1 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Baculo_PP31 PF05311.6 CDI87658.1 - 8.1 5.6 14.3 8.4 5.5 9.9 1.0 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) Peptidase_U57 PF05582.7 CDI87658.1 - 8.6 5.2 11.6 8.8 5.1 8.0 1.0 1 0 0 1 1 1 0 YabG peptidase U57 SeqA PF03925.8 CDI87658.1 - 9.4 5.8 12.8 10 5.7 8.9 1.1 1 0 0 1 1 1 0 SeqA protein Chorion_2 PF03964.10 CDI87659.1 - 0.013 16.0 1.4 0.021 15.3 1.0 1.4 1 0 0 1 1 1 0 Chorion family 2 Draxin PF15550.1 CDI87659.1 - 0.24 11.0 7.5 0.29 10.7 5.2 1.0 1 0 0 1 1 1 0 Draxin GP38 PF05268.6 CDI87659.1 - 0.34 10.2 4.8 0.45 9.8 3.3 1.1 1 0 0 1 1 1 0 Phage tail fibre adhesin Gp38 G-alpha PF00503.15 CDI87659.1 - 0.36 9.4 5.7 0.4 9.2 4.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit FimP PF09766.4 CDI87659.1 - 0.48 9.4 8.1 0.62 9.0 5.6 1.1 1 0 0 1 1 1 0 Fms-interacting protein DUF4228 PF14009.1 CDI87659.1 - 2.2 8.4 7.8 2.8 8.0 5.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4228) Spore_coat_CotO PF14153.1 CDI87659.1 - 6.6 6.1 16.2 9.6 5.6 11.2 1.3 1 0 0 1 1 1 0 Spore coat protein CotO Jun PF03957.8 CDI87660.1 - 3.1 7.4 17.5 5.1 6.7 12.1 1.3 1 0 0 1 1 1 0 Jun-like transcription factor ketoacyl-synt PF00109.21 CDI87661.1 - 9.1e-160 529.9 1.3 5.2e-80 268.5 0.1 2.6 2 0 0 2 2 2 2 Beta-ketoacyl synthase, N-terminal domain PS-DH PF14765.1 CDI87661.1 - 1.2e-85 287.2 10.0 6.1e-45 153.6 1.6 2.4 2 0 0 2 2 2 2 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.17 CDI87661.1 - 1.6e-82 273.1 1.0 7e-42 142.0 0.1 2.7 2 0 0 2 2 2 2 Beta-ketoacyl synthase, C-terminal domain Acyl_transf_1 PF00698.16 CDI87661.1 - 5e-58 196.9 0.2 1e-57 195.9 0.1 1.5 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.5 CDI87661.1 - 1.5e-29 102.9 0.5 2.3e-13 50.2 0.0 3.1 3 0 0 3 3 3 2 KR domain PP-binding PF00550.20 CDI87661.1 - 1.9e-27 95.2 0.0 2.8e-13 49.9 0.0 2.6 2 0 0 2 2 2 2 Phosphopantetheine attachment site adh_short PF00106.20 CDI87661.1 - 8e-20 71.4 0.1 2.2e-11 43.9 0.0 3.3 3 0 0 3 3 2 2 short chain dehydrogenase ADH_zinc_N PF00107.21 CDI87661.1 - 2.5e-16 59.3 0.0 9.7e-16 57.5 0.0 2.1 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 CDI87661.1 - 3.9e-12 45.8 11.2 2.4e-06 27.2 0.0 4.6 5 0 0 5 5 4 2 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 CDI87661.1 - 1.3e-09 39.0 0.0 2.7e-08 34.7 0.0 3.1 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Thiolase_N PF00108.18 CDI87661.1 - 5.9e-07 28.7 1.3 0.024 13.6 0.1 2.6 2 0 0 2 2 2 2 Thiolase, N-terminal domain Polysacc_synt_2 PF02719.10 CDI87661.1 - 0.037 12.9 0.0 0.067 12.0 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Epimerase PF01370.16 CDI87661.1 - 0.045 13.1 0.0 0.095 12.1 0.0 1.6 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family AlaDh_PNT_C PF01262.16 CDI87661.1 - 0.17 11.4 2.6 0.17 11.4 0.1 2.1 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain ELFV_dehydrog PF00208.16 CDI87661.1 - 0.39 10.2 2.0 3 7.3 0.0 2.5 2 0 0 2 2 2 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase efThoc1 PF11957.3 CDI87661.1 - 0.98 7.8 0.0 1.5 7.2 0.0 1.1 1 0 0 1 1 1 0 THO complex subunit 1 transcription elongation factor ACP_syn_III PF08545.5 CDI87661.1 - 4.2 7.0 8.7 41 3.9 1.2 3.6 2 1 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III TraT PF05818.7 CDI87662.1 - 0.0061 16.0 2.5 0.0076 15.7 1.7 1.1 1 0 0 1 1 1 1 Enterobacterial TraT complement resistance protein DUF4367 PF14285.1 CDI87662.1 - 0.049 12.9 0.5 0.061 12.6 0.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4367) Activator_LAG-3 PF11498.3 CDI87662.1 - 0.054 12.2 27.2 0.062 12.0 18.8 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Ctr PF04145.10 CDI87662.1 - 0.18 11.8 2.2 0.23 11.5 1.5 1.1 1 0 0 1 1 1 0 Ctr copper transporter family RskA PF10099.4 CDI87662.1 - 0.19 11.4 16.3 0.23 11.2 11.3 1.1 1 0 0 1 1 1 0 Anti-sigma-K factor rskA DUF4626 PF15422.1 CDI87662.1 - 0.38 10.7 1.8 0.41 10.5 1.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4626) AAA_23 PF13476.1 CDI87662.1 - 0.41 10.9 4.7 0.38 11.0 3.2 1.0 1 0 0 1 1 1 0 AAA domain Med15 PF09606.5 CDI87662.1 - 0.43 8.7 31.7 0.48 8.5 22.0 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF2232 PF09991.4 CDI87662.1 - 0.47 9.3 6.6 0.49 9.3 4.6 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) DUF4557 PF15101.1 CDI87662.1 - 0.54 10.0 13.3 0.62 9.8 9.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) Spt20 PF12090.3 CDI87662.1 - 0.54 9.5 6.0 0.5 9.6 4.2 1.1 1 0 0 1 1 1 0 Spt20 family CEP19 PF14933.1 CDI87662.1 - 0.85 9.9 6.2 0.89 9.8 4.3 1.1 1 0 0 1 1 1 0 CEP19-like protein FliP PF00813.15 CDI87662.1 - 1.2 8.7 5.6 1.3 8.7 3.9 1.0 1 0 0 1 1 1 0 FliP family eIF-4B PF06273.6 CDI87662.1 - 1.3 7.6 15.3 1.5 7.5 10.6 1.0 1 0 0 1 1 1 0 Plant specific eukaryotic initiation factor 4B DUF3520 PF12034.3 CDI87662.1 - 1.6 8.7 9.0 1.8 8.6 6.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3520) Serinc PF03348.10 CDI87662.1 - 1.8 7.1 5.2 1.8 7.1 3.6 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) DUF1176 PF06674.6 CDI87662.1 - 2.1 7.3 13.7 2.3 7.2 9.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1176) PMSI1 PF15322.1 CDI87662.1 - 2.6 7.0 9.5 2.9 6.8 6.6 1.0 1 0 0 1 1 1 0 Protein missing in infertile sperm 1, putative Suf PF05843.9 CDI87662.1 - 2.7 7.6 10.8 3 7.5 7.5 1.0 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) eIF3_subunit PF08597.5 CDI87662.1 - 3.3 7.2 11.4 3.8 6.9 7.9 1.1 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit DUF3365 PF11845.3 CDI87662.1 - 4.1 7.2 11.3 4.5 7.0 7.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3365) PP2C_2 PF13672.1 CDI87662.1 - 5.6 6.2 11.1 5.9 6.2 7.7 1.0 1 0 0 1 1 1 0 Protein phosphatase 2C DUF3676 PF12429.3 CDI87662.1 - 7 6.1 14.5 7.6 6.0 10.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3676) DUF3617 PF12276.3 CDI87662.1 - 7.4 6.0 14.5 11 5.4 10.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3617) R_equi_Vir PF05526.6 CDI87662.1 - 7.9 6.0 9.9 9.1 5.8 6.8 1.1 1 0 0 1 1 1 0 Rhodococcus equi virulence-associated protein GN3L_Grn1 PF08701.6 CDI87662.1 - 8.2 6.4 12.6 11 5.9 8.8 1.2 1 0 0 1 1 1 0 GNL3L/Grn1 putative GTPase PAT1 PF09770.4 CDI87662.1 - 8.8 4.4 25.0 9.3 4.3 17.3 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF3533 PF12051.3 CDI87662.1 - 9.1 4.9 9.8 10 4.7 6.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3533) Helicase_C PF00271.26 CDI87664.1 - 2e-23 82.0 0.1 5.2e-23 80.6 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain GUCT PF08152.7 CDI87664.1 - 3.8e-07 30.0 0.0 1.7e-06 27.8 0.0 2.1 1 1 0 1 1 1 1 GUCT (NUC152) domain Spt20 PF12090.3 CDI87665.1 - 0.015 14.6 0.3 0.015 14.6 0.2 1.2 1 0 0 1 1 1 0 Spt20 family Suf PF05843.9 CDI87665.1 - 0.084 12.5 2.1 0.091 12.4 1.4 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Med15 PF09606.5 CDI87665.1 - 0.15 10.2 18.2 0.17 10.0 12.6 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal RAB3GAP2_N PF14655.1 CDI87665.1 - 0.15 11.0 3.0 0.16 10.9 2.1 1.2 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus TraT PF05818.7 CDI87665.1 - 0.3 10.4 9.3 0.46 9.8 6.5 1.3 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein MSP1_C PF07462.6 CDI87665.1 - 0.64 8.3 14.2 0.77 8.0 9.9 1.1 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Silic_transp PF03842.8 CDI87665.1 - 0.81 7.6 3.0 0.96 7.4 2.0 1.1 1 0 0 1 1 1 0 Silicon transporter Ctr PF04145.10 CDI87665.1 - 1.2 9.2 7.9 6.6 6.7 1.6 2.1 1 1 1 2 2 2 0 Ctr copper transporter family PAT1 PF09770.4 CDI87665.1 - 2.6 6.1 14.4 2.9 5.9 10.0 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 MSP1_C PF07462.6 CDI87666.1 - 0.57 8.4 5.0 0.66 8.2 3.5 1.0 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Bac_luciferase PF00296.15 CDI87666.1 - 0.71 8.9 7.5 0.79 8.7 5.2 1.0 1 0 0 1 1 1 0 Luciferase-like monooxygenase BAF1_ABF1 PF04684.8 CDI87668.1 - 7.4 5.3 12.0 8.4 5.1 8.4 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor zf-RING_3 PF14369.1 CDI87669.1 - 6.2e-05 22.9 1.2 0.001 19.0 0.8 2.3 1 1 0 1 1 1 1 zinc-finger CDC45 PF02724.9 CDI87669.1 - 0.011 13.8 0.6 0.0088 14.1 0.4 1.2 1 0 0 1 1 1 0 CDC45-like protein zf-NADH-PPase PF09297.6 CDI87669.1 - 0.18 11.3 0.2 0.18 11.3 0.1 2.0 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain Lar_restr_allev PF14354.1 CDI87669.1 - 2.8 8.3 8.4 7.3 6.9 0.5 2.6 1 1 1 2 2 2 0 Restriction alleviation protein Lar Chromo PF00385.19 CDI87670.1 - 5.6e-14 51.5 0.0 8.1e-14 51.0 0.0 1.3 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain DUF1674 PF07896.7 CDI87671.1 - 5.3e-07 29.7 12.2 2.7e-06 27.4 8.5 2.2 1 1 0 1 1 1 1 Protein of unknown function (DUF1674) DUF3373 PF11853.3 CDI87671.1 - 4.4e-05 22.1 6.2 5.5e-05 21.9 4.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3373) RskA PF10099.4 CDI87671.1 - 0.00035 20.3 2.5 0.00041 20.1 1.7 1.1 1 0 0 1 1 1 1 Anti-sigma-K factor rskA Chorion_2 PF03964.10 CDI87671.1 - 0.0061 17.0 7.7 0.009 16.5 5.3 1.3 1 0 0 1 1 1 1 Chorion family 2 SR-25 PF10500.4 CDI87671.1 - 0.0084 15.6 12.8 0.01 15.3 8.9 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein U79_P34 PF03064.11 CDI87671.1 - 0.011 15.2 9.2 0.012 15.1 6.4 1.1 1 0 0 1 1 1 0 HSV U79 / HCMV P34 CDK2AP PF09806.4 CDI87671.1 - 0.018 15.2 13.1 0.022 15.0 9.1 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein CAF-1_p150 PF11600.3 CDI87671.1 - 0.019 14.3 17.1 0.022 14.1 11.8 1.0 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal FHIPEP PF00771.15 CDI87671.1 - 0.03 12.6 3.3 0.032 12.5 2.3 1.1 1 0 0 1 1 1 0 FHIPEP family CD20 PF04103.10 CDI87671.1 - 0.037 13.9 0.1 0.045 13.6 0.1 1.1 1 0 0 1 1 1 0 CD20-like family Spt20 PF12090.3 CDI87671.1 - 0.049 12.9 10.9 0.067 12.5 7.6 1.3 1 0 0 1 1 1 0 Spt20 family FLO_LFY PF01698.11 CDI87671.1 - 0.056 12.2 13.6 0.063 12.1 9.5 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein PAT1 PF09770.4 CDI87671.1 - 0.077 11.2 22.8 0.075 11.2 15.8 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Med19 PF10278.4 CDI87671.1 - 0.11 12.2 9.9 0.13 11.9 6.9 1.1 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 Ebola_NP PF05505.7 CDI87671.1 - 0.14 10.1 9.6 0.16 10.0 6.7 1.0 1 0 0 1 1 1 0 Ebola nucleoprotein Gag_spuma PF03276.9 CDI87671.1 - 0.15 10.3 20.4 0.17 10.2 14.1 1.1 1 0 0 1 1 1 0 Spumavirus gag protein SET PF00856.23 CDI87671.1 - 0.16 12.3 2.4 0.18 12.1 1.7 1.2 1 0 0 1 1 1 0 SET domain Pex14_N PF04695.8 CDI87671.1 - 0.21 11.6 12.3 0.26 11.3 8.5 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Hamartin PF04388.7 CDI87671.1 - 0.22 10.1 7.6 0.24 10.0 5.2 1.0 1 0 0 1 1 1 0 Hamartin protein TFIIA PF03153.8 CDI87671.1 - 0.23 11.2 22.1 0.25 11.2 15.3 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit FimP PF09766.4 CDI87671.1 - 0.25 10.3 18.8 0.27 10.2 13.1 1.1 1 0 0 1 1 1 0 Fms-interacting protein EPL1 PF10513.4 CDI87671.1 - 0.27 11.4 10.2 0.32 11.2 7.0 1.2 1 0 0 1 1 1 0 Enhancer of polycomb-like Med13_N PF11597.3 CDI87671.1 - 0.33 9.5 8.9 0.35 9.4 6.2 1.0 1 0 0 1 1 1 0 Mediator complex subunit 13 N-terminal DUF2681 PF10883.3 CDI87671.1 - 0.37 11.0 13.5 0.48 10.6 9.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) DUF4175 PF13779.1 CDI87671.1 - 0.38 8.3 23.5 0.4 8.3 16.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) eIF-3_zeta PF05091.7 CDI87671.1 - 0.38 9.3 10.8 0.37 9.3 7.5 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Aminotran_1_2 PF00155.16 CDI87671.1 - 0.39 9.6 4.9 0.44 9.4 3.4 1.1 1 0 0 1 1 1 0 Aminotransferase class I and II Activator_LAG-3 PF11498.3 CDI87671.1 - 0.39 9.4 23.8 0.41 9.3 16.5 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 DDHD PF02862.12 CDI87671.1 - 0.41 10.4 13.8 0.45 10.2 9.5 1.1 1 0 0 1 1 1 0 DDHD domain FYDLN_acid PF09538.5 CDI87671.1 - 0.43 11.1 7.3 0.57 10.7 5.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) DUF966 PF06136.8 CDI87671.1 - 0.46 9.8 10.4 0.48 9.7 7.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) DUF1510 PF07423.6 CDI87671.1 - 0.51 9.6 15.0 0.57 9.5 10.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) VIT1 PF01988.14 CDI87671.1 - 0.58 9.5 2.6 0.68 9.3 1.8 1.1 1 0 0 1 1 1 0 VIT family IncA PF04156.9 CDI87671.1 - 0.59 9.7 12.4 0.65 9.5 8.6 1.1 1 0 0 1 1 1 0 IncA protein Presenilin PF01080.12 CDI87671.1 - 0.61 8.8 12.0 0.68 8.6 8.3 1.0 1 0 0 1 1 1 0 Presenilin Androgen_recep PF02166.11 CDI87671.1 - 0.66 8.7 12.8 0.84 8.4 8.8 1.2 1 0 0 1 1 1 0 Androgen receptor Peptidase_S49_N PF08496.5 CDI87671.1 - 0.72 9.6 8.0 0.79 9.5 5.6 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Herpes_TAF50 PF03326.8 CDI87671.1 - 0.76 8.6 15.5 0.87 8.4 10.7 1.0 1 0 0 1 1 1 0 Herpesvirus transcription activation factor (transactivator) ORC6 PF05460.8 CDI87671.1 - 0.82 8.7 11.3 0.96 8.4 7.8 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) RAB3GAP2_N PF14655.1 CDI87671.1 - 0.83 8.5 9.4 0.89 8.4 6.5 1.2 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Myf5 PF12232.3 CDI87671.1 - 0.92 10.1 4.6 1.6 9.4 3.2 1.5 1 1 0 1 1 1 0 Myogenic determination factor 5 DUF3408 PF11888.3 CDI87671.1 - 0.94 9.4 10.7 1.4 8.8 7.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) DUF3987 PF13148.1 CDI87671.1 - 0.97 7.9 8.7 1.1 7.7 6.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) Med15 PF09606.5 CDI87671.1 - 1 7.4 27.4 1 7.4 19.0 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Serinc PF03348.10 CDI87671.1 - 1.1 7.8 9.9 1.2 7.7 6.8 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) Ycf1 PF05758.7 CDI87671.1 - 1.2 6.7 11.5 1.2 6.7 7.9 1.0 1 0 0 1 1 1 0 Ycf1 DDRGK PF09756.4 CDI87671.1 - 1.2 8.4 16.8 1.6 8.0 11.6 1.1 1 0 0 1 1 1 0 DDRGK domain NARP1 PF12569.3 CDI87671.1 - 1.3 7.7 15.6 1.4 7.5 10.8 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 GAGA_bind PF06217.7 CDI87671.1 - 1.3 8.9 12.0 1.4 8.7 8.3 1.0 1 0 0 1 1 1 0 GAGA binding protein-like family PPP4R2 PF09184.6 CDI87671.1 - 1.3 8.4 13.0 1.6 8.2 9.0 1.1 1 0 0 1 1 1 0 PPP4R2 Sporozoite_P67 PF05642.6 CDI87671.1 - 1.4 6.7 7.3 1.7 6.3 5.1 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen zf-DHHC PF01529.15 CDI87671.1 - 1.9 7.8 5.3 2.2 7.6 3.7 1.2 1 0 0 1 1 1 0 DHHC palmitoyltransferase R_equi_Vir PF05526.6 CDI87671.1 - 2 8.0 5.7 2.5 7.6 4.0 1.2 1 0 0 1 1 1 0 Rhodococcus equi virulence-associated protein Cellulose_synt PF03552.9 CDI87671.1 - 2 6.5 6.4 2.2 6.4 4.4 1.0 1 0 0 1 1 1 0 Cellulose synthase Hid1 PF12722.2 CDI87671.1 - 2.1 5.9 12.8 2.1 5.9 8.9 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein PIH1 PF08190.7 CDI87671.1 - 2.4 7.5 14.5 2.6 7.4 10.0 1.1 1 0 0 1 1 1 0 pre-RNA processing PIH1/Nop17 Prog_receptor PF02161.10 CDI87671.1 - 2.6 6.7 12.1 3.2 6.4 8.4 1.1 1 0 0 1 1 1 0 Progesterone receptor Afi1 PF07792.7 CDI87671.1 - 3 7.8 12.4 3.5 7.6 8.6 1.2 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Folate_carrier PF01770.13 CDI87671.1 - 3 6.2 5.2 3.4 6.0 3.6 1.1 1 0 0 1 1 1 0 Reduced folate carrier BTV_NS2 PF04514.7 CDI87671.1 - 3 6.6 11.2 3.4 6.4 7.8 1.0 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Tim54 PF11711.3 CDI87671.1 - 3.2 6.2 10.5 3.6 6.0 7.3 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Spore_coat_CotO PF14153.1 CDI87671.1 - 3.4 7.0 20.6 4.5 6.6 14.3 1.1 1 0 0 1 1 1 0 Spore coat protein CotO SAPS PF04499.10 CDI87671.1 - 3.5 6.1 10.7 3.6 6.1 7.4 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Raftlin PF15250.1 CDI87671.1 - 3.5 6.0 12.4 3.8 5.9 8.6 1.0 1 0 0 1 1 1 0 Raftlin CDC45 PF02724.9 CDI87671.1 - 4.2 5.2 12.9 4.4 5.2 8.9 1.0 1 0 0 1 1 1 0 CDC45-like protein Neur_chan_memb PF02932.11 CDI87671.1 - 4.3 7.1 7.8 4.7 7.0 5.4 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF4407 PF14362.1 CDI87671.1 - 4.3 6.1 14.0 4.9 6.0 9.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) RR_TM4-6 PF06459.7 CDI87671.1 - 4.5 7.0 15.7 5.2 6.8 10.9 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 FNIP_N PF14636.1 CDI87671.1 - 5 7.6 13.7 6.2 7.2 9.5 1.2 1 0 0 1 1 1 0 Folliculin-interacting protein N-terminus G-alpha PF00503.15 CDI87671.1 - 5.7 5.5 12.4 6.5 5.3 8.6 1.2 1 0 0 1 1 1 0 G-protein alpha subunit HA2 PF04408.18 CDI87671.1 - 6 6.9 6.4 9.7 6.2 4.5 1.4 1 1 0 1 1 1 0 Helicase associated domain (HA2) Senescence_reg PF04520.8 CDI87671.1 - 6.2 7.2 11.1 9 6.7 7.7 1.3 1 0 0 1 1 1 0 Senescence regulator EIIBC-GUT_N PF03612.9 CDI87671.1 - 6.4 6.3 8.9 7.7 6.0 6.2 1.3 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Sox_N PF12444.3 CDI87671.1 - 6.6 7.9 10.7 10 7.3 7.4 1.4 1 0 0 1 1 1 0 Sox developmental protein N terminal Sec62 PF03839.11 CDI87671.1 - 6.8 6.0 10.3 7.9 5.8 7.1 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 Macoilin PF09726.4 CDI87671.1 - 6.8 4.8 12.9 7.4 4.7 9.0 1.0 1 0 0 1 1 1 0 Transmembrane protein DUF775 PF05603.7 CDI87671.1 - 7.3 6.0 14.5 9 5.7 10.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF775) Paf1 PF03985.8 CDI87671.1 - 7.4 5.1 15.4 8.1 5.0 10.7 1.1 1 0 0 1 1 1 0 Paf1 Suf PF05843.9 CDI87671.1 - 8.2 6.0 16.5 9.7 5.8 11.4 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Calc_CGRP_IAPP PF00214.14 CDI87671.1 - 8.6 6.4 11.4 12 5.9 7.9 1.2 1 0 0 1 1 1 0 Calcitonin / CGRP / IAPP family Band_3_cyto PF07565.8 CDI87671.1 - 8.8 5.7 12.3 10 5.5 8.6 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Pex26 PF07163.7 CDI87671.1 - 8.8 5.1 9.3 10 4.9 6.4 1.2 1 0 0 1 1 1 0 Pex26 protein DUF4557 PF15101.1 CDI87671.1 - 9.8 5.9 19.1 12 5.7 13.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) Thioredoxin PF00085.15 CDI87672.1 - 4.2e-05 23.1 0.1 7.2e-05 22.4 0.1 1.4 1 0 0 1 1 1 1 Thioredoxin DUF3530 PF12048.3 CDI87672.1 - 0.0044 16.0 2.0 0.0048 15.9 1.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3530) Chloroplast_duf PF14476.1 CDI87672.1 - 1.8 7.2 6.9 2.2 7.0 4.8 1.1 1 0 0 1 1 1 0 Petal formation-expressed DUF3138 PF11336.3 CDI87672.1 - 2.6 6.1 7.4 2.8 6.0 5.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) DUF2782 PF11191.3 CDI87672.1 - 3.7 7.5 5.1 6 6.8 3.6 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2782) BAF1_ABF1 PF04684.8 CDI87672.1 - 6.6 5.4 6.3 7.6 5.2 4.4 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Tropomyosin_1 PF12718.2 CDI87674.1 - 0.27 11.0 27.1 0.42 10.4 18.8 1.5 1 1 0 1 1 1 0 Tropomyosin like IncA PF04156.9 CDI87674.1 - 0.38 10.3 18.6 0.47 10.0 12.9 1.2 1 0 0 1 1 1 0 IncA protein ERM PF00769.14 CDI87674.1 - 0.44 10.0 28.8 0.48 9.9 20.0 1.0 1 0 0 1 1 1 0 Ezrin/radixin/moesin family HAUS-augmin3 PF14932.1 CDI87674.1 - 0.94 8.6 21.7 1.1 8.3 15.0 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 DUF1759 PF03564.10 CDI87674.1 - 0.98 9.2 8.6 2.4 7.9 5.7 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1759) Mnd1 PF03962.10 CDI87674.1 - 1.7 8.2 16.6 2.2 7.8 11.5 1.3 1 0 0 1 1 1 0 Mnd1 family Mgr1 PF08602.5 CDI87674.1 - 2.1 7.2 8.5 2.2 7.1 5.9 1.0 1 0 0 1 1 1 0 Mgr1-like, i-AAA protease complex subunit DUF1788 PF08747.6 CDI87674.1 - 2.7 7.8 4.7 3.9 7.3 3.1 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF1788) Bap31 PF05529.7 CDI87674.1 - 4.4 6.7 14.2 5 6.5 9.8 1.2 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like AAA_13 PF13166.1 CDI87674.1 - 4.8 5.5 14.6 5.2 5.3 10.1 1.1 1 0 0 1 1 1 0 AAA domain APG6 PF04111.7 CDI87674.1 - 4.8 6.1 19.6 6 5.8 13.6 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 Prominin PF05478.6 CDI87674.1 - 7.8 3.8 9.7 7.9 3.8 6.7 1.0 1 0 0 1 1 1 0 Prominin DUF2317 PF10079.4 CDI87674.1 - 9 4.7 16.3 11 4.4 11.3 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2317) DUF3584 PF12128.3 CDI87674.1 - 9.3 3.4 25.4 11 3.2 17.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF1645 PF07816.6 CDI87676.1 - 0.0014 19.1 4.7 0.0019 18.6 3.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1645) SR-25 PF10500.4 CDI87676.1 - 0.0033 16.9 10.2 0.004 16.6 7.0 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Rhomboid_SP PF12595.3 CDI87676.1 - 0.0075 15.8 1.1 0.0085 15.7 0.8 1.2 1 0 0 1 1 1 1 Rhomboid serine protease DUF3446 PF11928.3 CDI87676.1 - 0.035 14.2 7.3 0.059 13.5 5.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3446) TMEM247 PF15444.1 CDI87676.1 - 0.27 11.0 1.6 0.35 10.6 0.9 1.4 1 1 0 1 1 1 0 Transmembrane protein 247 Myosin_head PF00063.16 CDI87677.1 - 0.35 8.8 0.0 12 3.8 0.0 2.0 2 0 0 2 2 2 0 Myosin head (motor domain) DUF2294 PF10057.4 CDI87679.1 - 0.002 17.7 3.3 0.0082 15.7 2.3 2.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2294) DUF1510 PF07423.6 CDI87681.1 - 0.0002 20.7 13.3 0.00025 20.4 9.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) Zip PF02535.17 CDI87681.1 - 0.00063 18.8 12.9 0.00089 18.3 9.0 1.3 1 0 0 1 1 1 1 ZIP Zinc transporter SpoIIIAH PF12685.2 CDI87681.1 - 0.0017 17.9 4.9 0.0028 17.1 3.4 1.4 1 0 0 1 1 1 1 SpoIIIAH-like protein TRAP_alpha PF03896.11 CDI87681.1 - 0.0024 16.9 3.0 0.003 16.6 2.1 1.2 1 0 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit NicO PF03824.11 CDI87681.1 - 0.039 13.2 8.7 0.046 13.0 6.0 1.1 1 0 0 1 1 1 0 High-affinity nickel-transport protein Peptidase_S49_N PF08496.5 CDI87681.1 - 0.059 13.1 17.6 0.081 12.7 12.2 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal FAM60A PF15396.1 CDI87681.1 - 0.089 12.5 17.9 0.12 12.1 12.4 1.0 1 0 0 1 1 1 0 Protein Family FAM60A ETRAMP PF09716.5 CDI87681.1 - 0.094 12.6 0.7 0.28 11.1 0.5 1.8 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) DUF1183 PF06682.7 CDI87681.1 - 0.096 12.2 8.8 0.12 11.9 6.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) Ni_hydr_CYTB PF01292.15 CDI87681.1 - 0.17 11.2 0.7 0.38 10.1 0.5 1.7 1 1 0 1 1 1 0 Prokaryotic cytochrome b561 SID-1_RNA_chan PF13965.1 CDI87681.1 - 0.19 9.8 11.1 0.2 9.7 7.7 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Ycf1 PF05758.7 CDI87681.1 - 0.28 8.8 16.8 0.29 8.7 11.6 1.0 1 0 0 1 1 1 0 Ycf1 Mem_trans PF03547.13 CDI87681.1 - 0.29 9.3 8.5 0.34 9.1 5.9 1.0 1 0 0 1 1 1 0 Membrane transport protein HCO3_cotransp PF00955.16 CDI87681.1 - 0.52 8.8 7.1 0.56 8.8 5.0 1.0 1 0 0 1 1 1 0 HCO3- transporter family FliP PF00813.15 CDI87681.1 - 0.59 9.8 9.3 0.76 9.4 6.4 1.2 1 0 0 1 1 1 0 FliP family DUF3260 PF11658.3 CDI87681.1 - 0.61 8.1 16.5 0.74 7.8 11.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3260) CKAP2_C PF15297.1 CDI87681.1 - 0.87 8.3 20.2 1 8.0 14.0 1.0 1 0 0 1 1 1 0 Cytoskeleton-associated protein 2 C-terminus RP-C_C PF11800.3 CDI87681.1 - 0.92 9.1 17.4 1.2 8.7 12.0 1.3 1 0 0 1 1 1 0 Replication protein C C-terminal region DUF4220 PF13968.1 CDI87681.1 - 1.1 8.3 8.4 1.2 8.1 5.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4220) ExbD PF02472.11 CDI87681.1 - 1.1 9.2 8.3 1.5 8.8 5.8 1.2 1 0 0 1 1 1 0 Biopolymer transport protein ExbD/TolR DUF4446 PF14584.1 CDI87681.1 - 1.5 8.6 16.1 3 7.6 11.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF4446) Otopetrin PF03189.8 CDI87681.1 - 1.6 7.6 11.4 2.6 6.9 7.9 1.3 1 0 0 1 1 1 0 Otopetrin Tim54 PF11711.3 CDI87681.1 - 1.7 7.1 12.7 1.9 6.9 8.8 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Herpes_DNAp_acc PF04929.7 CDI87681.1 - 1.7 7.5 16.9 2.1 7.2 11.7 1.0 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Conotoxin PF02950.12 CDI87681.1 - 1.7 9.4 27.0 1.5e+04 -5.6 18.7 2.3 1 1 0 1 1 0 0 Conotoxin Band_3_cyto PF07565.8 CDI87681.1 - 1.9 7.9 28.0 2.4 7.5 19.4 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain NARP1 PF12569.3 CDI87681.1 - 2 7.0 21.0 2.5 6.7 14.5 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Suf PF05843.9 CDI87681.1 - 2.1 8.0 30.2 3.3 7.3 20.9 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF605 PF04652.11 CDI87681.1 - 2.3 7.5 27.9 3.1 7.1 19.3 1.1 1 0 0 1 1 1 0 Vta1 like Rtf2 PF04641.7 CDI87681.1 - 2.5 7.2 19.0 3.1 6.9 13.2 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger DUF4638 PF15472.1 CDI87681.1 - 2.7 7.5 17.1 3.2 7.2 11.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) Hid1 PF12722.2 CDI87681.1 - 2.8 5.5 21.9 3.3 5.2 15.2 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein GRP PF07172.6 CDI87681.1 - 3.4 8.2 15.6 49 4.4 10.8 2.1 1 1 0 1 1 1 0 Glycine rich protein family DUF2126 PF09899.4 CDI87681.1 - 3.4 5.5 15.6 4.8 5.0 10.8 1.3 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) MDFI PF15316.1 CDI87681.1 - 3.5 7.5 14.9 5.2 7.0 10.3 1.3 1 0 0 1 1 1 0 MyoD family inhibitor Raftlin PF15250.1 CDI87681.1 - 3.9 5.8 21.4 4.6 5.6 14.9 1.0 1 0 0 1 1 1 0 Raftlin DUF1387 PF07139.6 CDI87681.1 - 4.2 6.8 16.1 5.2 6.5 11.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) BPL_N PF09825.4 CDI87681.1 - 4.5 5.9 10.8 5.1 5.7 7.5 1.0 1 0 0 1 1 1 0 Biotin-protein ligase, N terminal DUF3708 PF12501.3 CDI87681.1 - 4.6 7.0 7.5 6.8 6.5 5.2 1.3 1 0 0 1 1 1 0 Phosphate ATP-binding cassette transporter GNT-I PF03071.10 CDI87681.1 - 4.7 5.6 13.0 5.4 5.4 9.0 1.0 1 0 0 1 1 1 0 GNT-I family YABBY PF04690.8 CDI87681.1 - 5 7.3 18.0 7.1 6.8 12.5 1.3 1 0 0 1 1 1 0 YABBY protein AUX_IAA PF02309.11 CDI87681.1 - 7 6.3 18.6 8.9 5.9 12.9 1.1 1 0 0 1 1 1 0 AUX/IAA family Peroxin-13_N PF04088.8 CDI87681.1 - 7.2 6.5 14.6 17 5.3 2.6 2.1 1 1 1 2 2 2 0 Peroxin 13, N-terminal region RskA PF10099.4 CDI87681.1 - 7.5 6.2 13.9 4.8e+02 0.3 9.0 2.3 1 1 0 1 1 1 0 Anti-sigma-K factor rskA Herpes_UL87 PF03043.9 CDI87681.1 - 7.5 4.8 14.0 8.8 4.5 9.7 1.0 1 0 0 1 1 1 0 Herpesvirus UL87 family CDC45 PF02724.9 CDI87681.1 - 7.9 4.3 21.8 9.7 4.0 15.1 1.0 1 0 0 1 1 1 0 CDC45-like protein Ndc1_Nup PF09531.5 CDI87681.1 - 8.4 4.6 17.0 11 4.2 11.8 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Membralin PF09746.4 CDI87681.1 - 9.7 5.1 9.5 12 4.8 6.6 1.1 1 0 0 1 1 1 0 Tumour-associated protein DUF4045 PF13254.1 CDI87681.1 - 9.9 5.3 20.4 12 5.0 14.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) bZIP_1 PF00170.16 CDI87682.1 - 9.9 6.2 15.1 3.4 7.6 0.5 4.0 2 1 2 4 4 4 0 bZIP transcription factor Mpp10 PF04006.7 CDI87683.1 - 0.49 8.7 22.1 0.52 8.6 15.3 1.0 1 0 0 1 1 1 0 Mpp10 protein BSP_II PF05432.6 CDI87683.1 - 0.56 9.4 16.6 0.61 9.3 11.5 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) DUF2890 PF11081.3 CDI87683.1 - 2 8.4 22.8 2.1 8.3 15.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) NOA36 PF06524.7 CDI87683.1 - 2.4 7.3 8.9 2.4 7.3 6.2 1.1 1 0 0 1 1 1 0 NOA36 protein ANAPC15 PF15243.1 CDI87683.1 - 2.7 8.1 25.7 4.1 7.5 17.8 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 15 Nop53 PF07767.6 CDI87683.1 - 4.3 6.2 26.3 5.5 5.8 18.2 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) DBINO PF13892.1 CDI87683.1 - 6.9 6.7 22.0 8.6 6.3 15.3 1.2 1 1 0 1 1 1 0 DNA-binding domain CENP-B_dimeris PF09026.5 CDI87683.1 - 7.3 6.8 13.3 11 6.3 9.2 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Nop25 PF09805.4 CDI87683.1 - 8.6 6.4 25.5 9.7 6.2 17.7 1.1 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) SDP_N PF12278.3 CDI87684.1 - 0.04 13.5 0.9 0.051 13.2 0.6 1.2 1 0 0 1 1 1 0 Sex determination protein N terminal DUF1183 PF06682.7 CDI87684.1 - 0.07 12.7 7.4 0.087 12.4 5.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) DDRGK PF09756.4 CDI87684.1 - 0.11 11.8 3.6 0.13 11.6 2.5 1.2 1 0 0 1 1 1 0 DDRGK domain LCD1 PF09798.4 CDI87684.1 - 0.13 10.1 7.3 0.16 9.9 5.1 1.0 1 0 0 1 1 1 0 DNA damage checkpoint protein Shadoo PF14999.1 CDI87684.1 - 0.17 11.7 5.8 0.26 11.1 4.0 1.3 1 0 0 1 1 1 0 Shadow of prion protein, neuroprotective eIF-3_zeta PF05091.7 CDI87684.1 - 0.34 9.4 7.8 0.37 9.3 5.4 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF966 PF06136.8 CDI87684.1 - 0.36 10.2 11.3 0.43 9.9 7.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF966) MDFI PF15316.1 CDI87684.1 - 0.41 10.6 9.4 0.54 10.2 6.5 1.3 1 0 0 1 1 1 0 MyoD family inhibitor FAM60A PF15396.1 CDI87684.1 - 0.9 9.2 8.7 1.1 8.9 6.0 1.1 1 0 0 1 1 1 0 Protein Family FAM60A Gly-zipper_OmpA PF13436.1 CDI87684.1 - 0.97 9.1 21.1 5.8 6.6 14.7 1.9 1 1 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain Macoilin PF09726.4 CDI87684.1 - 1.1 7.4 13.7 1.2 7.2 9.5 1.0 1 0 0 1 1 1 0 Transmembrane protein DNA_pol_viral_N PF00242.12 CDI87684.1 - 1.8 7.4 15.8 2.1 7.2 10.9 1.0 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain Glyco_hydro_3_C PF01915.17 CDI87684.1 - 1.9 7.9 9.0 12 5.3 6.0 1.8 1 1 1 2 2 2 0 Glycosyl hydrolase family 3 C-terminal domain VID27 PF08553.5 CDI87684.1 - 2.1 6.4 8.8 2.5 6.2 6.1 1.0 1 0 0 1 1 1 0 VID27 cytoplasmic protein CDK2AP PF09806.4 CDI87684.1 - 2.1 8.5 17.5 3.3 7.9 12.1 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein MMR1 PF08505.5 CDI87684.1 - 2.2 8.2 14.5 2.6 8.0 10.0 1.1 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein NST1 PF13945.1 CDI87684.1 - 2.4 8.2 15.8 3 7.8 11.0 1.1 1 0 0 1 1 1 0 Salt tolerance down-regulator MAT1 PF06391.8 CDI87684.1 - 2.5 7.6 8.6 3.3 7.2 6.0 1.1 1 0 0 1 1 1 0 CDK-activating kinase assembly factor MAT1 MRP-S31 PF15433.1 CDI87684.1 - 2.7 7.3 11.3 3.5 6.9 7.8 1.2 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 Gly_rich PF12810.2 CDI87684.1 - 2.9 7.4 8.1 0.33 10.5 2.5 1.5 1 1 1 2 2 2 0 Glycine rich protein Neogenin_C PF06583.7 CDI87684.1 - 2.9 7.3 14.3 3.6 7.0 9.9 1.0 1 0 0 1 1 1 0 Neogenin C-terminus Ndc1_Nup PF09531.5 CDI87684.1 - 3 6.1 10.0 3.6 5.9 7.0 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Senescence_reg PF04520.8 CDI87684.1 - 4.1 7.8 9.0 6.1 7.3 6.2 1.2 1 0 0 1 1 1 0 Senescence regulator Pex14_N PF04695.8 CDI87684.1 - 4.4 7.3 25.3 0.6 10.1 6.2 2.1 1 1 1 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF1510 PF07423.6 CDI87684.1 - 5.8 6.2 9.8 7.9 5.7 6.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DUF4647 PF15504.1 CDI87684.1 - 6.1 5.5 13.0 7 5.3 9.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4647) Asp-B-Hydro_N PF05279.6 CDI87684.1 - 6.6 6.4 6.6 8.2 6.1 4.6 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Neur_chan_memb PF02932.11 CDI87684.1 - 7.1 6.4 9.6 8.7 6.1 6.7 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region PAT1 PF09770.4 CDI87684.1 - 8.5 4.4 31.5 9.5 4.3 21.8 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF1510 PF07423.6 CDI87685.1 - 0.11 11.8 15.7 0.14 11.5 10.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DUF3474 PF11960.3 CDI87685.1 - 0.13 12.3 4.9 0.13 12.2 3.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3474) HGTP_anticodon2 PF12745.2 CDI87685.1 - 0.19 10.8 13.8 0.22 10.6 9.6 1.0 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs DUF1892 PF08987.5 CDI87685.1 - 0.51 10.3 7.6 3 7.8 0.3 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1892) CLPTM1 PF05602.7 CDI87685.1 - 0.58 8.8 6.0 0.69 8.5 4.2 1.2 1 0 0 1 1 1 0 Cleft lip and palate transmembrane protein 1 (CLPTM1) DUF3752 PF12572.3 CDI87685.1 - 0.7 9.9 18.4 0.86 9.7 12.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3752) Senescence_reg PF04520.8 CDI87685.1 - 0.93 9.9 7.2 1.1 9.7 5.0 1.1 1 0 0 1 1 1 0 Senescence regulator Afi1 PF07792.7 CDI87685.1 - 1.6 8.7 16.8 1.9 8.5 11.7 1.1 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking G-7-MTase PF12803.2 CDI87685.1 - 2.1 7.4 8.4 2.4 7.2 5.8 1.0 1 0 0 1 1 1 0 mRNA (guanine-7-)methyltransferase (G-7-MTase) Rtf2 PF04641.7 CDI87685.1 - 2.2 7.3 18.4 2.9 7.0 12.8 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger XAP5 PF04921.9 CDI87685.1 - 2.5 7.5 14.1 3 7.3 9.7 1.1 1 0 0 1 1 1 0 XAP5, circadian clock regulator Ycf1 PF05758.7 CDI87685.1 - 3.4 5.2 16.6 3.7 5.1 11.5 1.0 1 0 0 1 1 1 0 Ycf1 Paf1 PF03985.8 CDI87685.1 - 3.7 6.1 19.4 4.5 5.8 13.4 1.0 1 0 0 1 1 1 0 Paf1 Hid1 PF12722.2 CDI87685.1 - 3.8 5.0 16.2 4 5.0 11.2 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF3754 PF12576.3 CDI87685.1 - 4.9 6.7 7.9 4.9 6.7 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3754) DUF2215 PF10225.4 CDI87685.1 - 5.3 6.4 11.1 5.8 6.2 7.7 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) N6_N4_Mtase PF01555.13 CDI87685.1 - 6.7 6.1 8.3 9.3 5.6 5.7 1.2 1 0 0 1 1 1 0 DNA methylase UPF0565 PF10561.4 CDI87685.1 - 6.9 5.4 13.4 10 4.9 9.3 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0565 DUF2201_N PF13203.1 CDI87685.1 - 7.6 5.6 15.2 9.6 5.2 10.5 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain Herpes_DNAp_acc PF04929.7 CDI87685.1 - 8.3 5.2 14.9 9.1 5.1 10.3 1.0 1 0 0 1 1 1 0 Herpes DNA replication accessory factor DUF4175 PF13779.1 CDI87685.1 - 8.8 3.8 40.9 10 3.7 28.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Conotoxin PF02950.12 CDI87685.1 - 9.3 7.1 17.3 1e+03 0.5 12.0 2.2 1 1 0 1 1 1 0 Conotoxin RP-C_C PF11800.3 CDI87685.1 - 9.5 5.8 13.3 15 5.2 9.2 1.4 1 0 0 1 1 1 0 Replication protein C C-terminal region Na_trans_assoc PF06512.8 CDI87685.1 - 9.7 6.0 12.5 13 5.6 8.7 1.2 1 0 0 1 1 1 0 Sodium ion transport-associated AMP_N PF05195.11 CDI87686.1 - 0.093 12.1 0.1 0.22 10.8 0.0 1.7 1 1 0 1 1 1 0 Aminopeptidase P, N-terminal domain Pex14_N PF04695.8 CDI87686.1 - 0.92 9.5 10.2 1 9.3 3.1 2.1 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF3121 PF11319.3 CDI87686.1 - 0.92 8.9 6.3 1.4 8.3 4.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3121) Phostensin_N PF13916.1 CDI87686.1 - 8.6 6.4 15.2 3 7.9 0.1 2.3 2 0 0 2 2 2 0 PP1-regulatory protein, Phostensin N-terminal APC_CDC26 PF10471.4 CDI87686.1 - 10 6.9 18.5 15 6.4 0.2 2.4 3 0 0 3 3 3 0 Anaphase-promoting complex APC subunit 1 DUF1864 PF08933.6 CDI87688.1 - 0.5 8.8 8.7 0.5 8.8 6.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1864) Pex14_N PF04695.8 CDI87688.1 - 0.9 9.5 23.7 0.94 9.5 16.4 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region FAM176 PF14851.1 CDI87688.1 - 2.4 7.8 8.9 3.1 7.4 6.2 1.2 1 0 0 1 1 1 0 FAM176 family DUF3245 PF11595.3 CDI87688.1 - 3.9 7.7 17.4 5.2 7.3 12.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3245) DUF4407 PF14362.1 CDI87688.1 - 7.8 5.3 22.7 8.3 5.2 15.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF3464 PF11947.3 CDI87688.1 - 9.3 5.6 16.4 11 5.4 11.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) FYDLN_acid PF09538.5 CDI87688.1 - 9.9 6.7 9.9 11 6.6 6.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) DUF1510 PF07423.6 CDI87689.1 - 6.7 6.0 38.2 7.2 5.9 26.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) APC_CDC26 PF10471.4 CDI87692.1 - 0.088 13.5 4.6 0.1 13.3 3.2 1.2 1 0 0 1 1 1 0 Anaphase-promoting complex APC subunit 1 Carb_kinase PF01256.12 CDI87692.1 - 0.27 10.4 8.6 0.31 10.2 5.9 1.0 1 0 0 1 1 1 0 Carbohydrate kinase SR-25 PF10500.4 CDI87692.1 - 0.37 10.2 3.1 0.38 10.2 2.1 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Herpes_gE PF02480.11 CDI87692.1 - 0.7 8.0 4.3 0.83 7.8 3.0 1.0 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E TraT PF05818.7 CDI87692.1 - 0.84 9.0 13.0 0.96 8.8 9.0 1.1 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein BAF1_ABF1 PF04684.8 CDI87692.1 - 1.1 7.9 17.7 1.4 7.7 12.3 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Peptidase_M50 PF02163.17 CDI87692.1 - 1.3 7.9 4.2 1.5 7.7 2.9 1.1 1 0 0 1 1 1 0 Peptidase family M50 Herpes_capsid PF06112.6 CDI87692.1 - 1.4 8.9 5.4 1.6 8.7 3.8 1.1 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein WES_acyltransf PF03007.11 CDI87692.1 - 1.4 8.3 7.6 1.5 8.3 5.3 1.0 1 0 0 1 1 1 0 Wax ester synthase-like Acyl-CoA acyltransferase domain Spore_YhcN_YlaJ PF09580.5 CDI87692.1 - 2.6 8.1 8.0 2.8 8.0 5.6 1.1 1 0 0 1 1 1 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) PHD_3 PF13922.1 CDI87692.1 - 5.1 7.4 7.2 6.3 7.1 5.0 1.4 1 1 0 1 1 1 0 PHD domain of transcriptional enhancer, Asx CDK2AP PF09806.4 CDI87692.1 - 6.2 7.0 14.7 8.2 6.6 10.2 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein MARCKS PF02063.12 CDI87695.1 - 4.7 6.9 24.4 0.16 11.7 7.6 2.0 2 0 0 2 2 2 0 MARCKS family RskA PF10099.4 CDI87696.1 - 0.025 14.3 9.1 0.028 14.1 6.3 1.2 1 0 0 1 1 1 0 Anti-sigma-K factor rskA DUF4557 PF15101.1 CDI87696.1 - 0.47 10.2 16.2 0.49 10.1 11.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) Trp_oprn_chp PF09534.5 CDI87696.1 - 0.55 9.8 6.1 0.56 9.7 4.3 1.0 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Ribosomal_60s PF00428.14 CDI87696.1 - 0.59 10.5 12.8 0.88 10.0 8.9 1.3 1 0 0 1 1 1 0 60s Acidic ribosomal protein Porin_4 PF13609.1 CDI87696.1 - 0.59 9.5 2.9 0.62 9.5 2.0 1.1 1 0 0 1 1 1 0 Gram-negative porin Chorion_2 PF03964.10 CDI87696.1 - 0.89 10.1 8.3 1.1 9.8 5.8 1.2 1 0 0 1 1 1 0 Chorion family 2 Herpes_DNAp_acc PF04929.7 CDI87696.1 - 1.2 7.9 9.0 1.3 7.9 6.3 1.0 1 0 0 1 1 1 0 Herpes DNA replication accessory factor DUF3381 PF11861.3 CDI87696.1 - 1.4 8.3 10.2 1.5 8.3 7.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) DUF2992 PF11208.3 CDI87696.1 - 1.7 8.5 15.8 1.7 8.5 10.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2992) AAA_23 PF13476.1 CDI87696.1 - 2.9 8.1 12.3 2.8 8.2 8.5 1.0 1 0 0 1 1 1 0 AAA domain Adeno_PIX PF03955.9 CDI87696.1 - 2.9 8.4 9.2 3.2 8.3 6.4 1.1 1 0 0 1 1 1 0 Adenovirus hexon-associated protein (IX) AIF_C PF14721.1 CDI87696.1 - 3.9 7.7 7.6 4.7 7.4 5.2 1.1 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Band_3_cyto PF07565.8 CDI87696.1 - 4.3 6.7 9.2 4.3 6.7 6.4 1.0 1 0 0 1 1 1 0 Band 3 cytoplasmic domain KfrA_N PF11740.3 CDI87696.1 - 4.6 7.7 26.4 4.9 7.6 18.3 1.0 1 0 0 1 1 1 0 Plasmid replication region DNA-binding N-term Spt20 PF12090.3 CDI87696.1 - 6.1 6.1 10.1 6.8 5.9 7.0 1.3 1 0 0 1 1 1 0 Spt20 family R_equi_Vir PF05526.6 CDI87696.1 - 7.1 6.2 7.1 7.9 6.0 4.9 1.1 1 0 0 1 1 1 0 Rhodococcus equi virulence-associated protein EIF4E-T PF10477.4 CDI87696.1 - 7.5 5.2 13.5 7.4 5.2 9.4 1.0 1 0 0 1 1 1 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E FimP PF09766.4 CDI87696.1 - 8.1 5.4 18.7 8.7 5.3 13.0 1.0 1 0 0 1 1 1 0 Fms-interacting protein Suf PF05843.9 CDI87696.1 - 9.3 5.8 14.6 9.9 5.7 10.1 1.0 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF3464 PF11947.3 CDI87696.1 - 9.9 5.6 8.3 11 5.4 5.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) DUF3274 PF11678.3 CDI87698.1 - 0.11 11.6 8.9 0.13 11.4 6.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3274) U79_P34 PF03064.11 CDI87698.1 - 0.16 11.4 5.9 0.22 11.0 4.1 1.2 1 0 0 1 1 1 0 HSV U79 / HCMV P34 FLO_LFY PF01698.11 CDI87698.1 - 5.7 5.6 9.9 6 5.5 6.9 1.2 1 0 0 1 1 1 0 Floricaula / Leafy protein Cwf_Cwc_15 PF04889.7 CDI87698.1 - 7.1 6.2 14.7 8.9 5.9 10.2 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein MSP1_C PF07462.6 CDI87698.1 - 7.2 4.8 8.6 9.9 4.4 5.9 1.2 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus PBP1_TM PF14812.1 CDI87699.1 - 0.1 12.9 5.1 0.12 12.6 3.6 1.1 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal AIF_C PF14721.1 CDI87699.1 - 0.1 12.8 12.8 0.11 12.7 8.9 1.0 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Zip PF02535.17 CDI87699.1 - 0.15 11.0 16.8 0.15 11.0 11.6 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter DUF1448 PF07289.6 CDI87699.1 - 0.29 10.0 15.1 0.32 9.8 10.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1448) FYDLN_acid PF09538.5 CDI87699.1 - 0.34 11.4 10.0 0.42 11.2 6.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) DUF1510 PF07423.6 CDI87699.1 - 0.52 9.6 16.4 0.59 9.4 11.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) FimP PF09766.4 CDI87699.1 - 0.54 9.2 27.0 0.74 8.8 18.7 1.2 1 0 0 1 1 1 0 Fms-interacting protein DUF1764 PF08576.5 CDI87699.1 - 0.55 11.0 16.2 0.73 10.6 11.2 1.2 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) CDC45 PF02724.9 CDI87699.1 - 0.67 7.9 13.5 0.72 7.8 9.3 1.0 1 0 0 1 1 1 0 CDC45-like protein BTV_NS2 PF04514.7 CDI87699.1 - 0.69 8.7 11.2 0.73 8.6 7.8 1.0 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Trypan_glycop_C PF10659.4 CDI87699.1 - 0.71 10.2 12.3 1.1 9.5 8.5 1.3 1 0 0 1 1 1 0 Trypanosome variant surface glycoprotein C-terminal domain NinG PF05766.7 CDI87699.1 - 0.79 9.4 20.0 0.83 9.3 13.9 1.0 1 0 0 1 1 1 0 Bacteriophage Lambda NinG protein DUF2072 PF09845.4 CDI87699.1 - 1 9.2 10.7 1 9.2 7.4 1.0 1 0 0 1 1 1 0 Zn-ribbon containing protein (DUF2072) TCP PF03634.8 CDI87699.1 - 1.1 9.6 19.5 1.2 9.4 13.5 1.1 1 0 0 1 1 1 0 TCP family transcription factor WBS_methylT PF12589.3 CDI87699.1 - 1.1 9.7 17.3 1.6 9.2 12.0 1.2 1 0 0 1 1 1 0 Methyltransferase involved in Williams-Beuren syndrome SelP_N PF04592.9 CDI87699.1 - 1.2 8.4 24.0 1.2 8.4 16.7 1.0 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Glyco_transf_15 PF01793.11 CDI87699.1 - 1.3 7.8 15.4 1.5 7.7 10.7 1.0 1 0 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase PRTP PF01366.13 CDI87699.1 - 1.3 6.8 13.9 1.6 6.6 9.6 1.0 1 0 0 1 1 1 0 Herpesvirus processing and transport protein Tim54 PF11711.3 CDI87699.1 - 1.5 7.3 12.0 1.6 7.2 8.3 1.0 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Tetraspannin PF00335.15 CDI87699.1 - 1.5 8.0 5.5 1.8 7.8 3.8 1.2 1 0 0 1 1 1 0 Tetraspanin family DHHW PF14286.1 CDI87699.1 - 1.7 7.8 14.1 1.7 7.8 9.8 1.0 1 0 0 1 1 1 0 DHHW protein NPR3 PF03666.8 CDI87699.1 - 1.7 7.0 16.1 1.9 6.8 11.2 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF4337 PF14235.1 CDI87699.1 - 1.8 8.3 18.0 2.1 8.1 12.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) RNA_pol_Rpc4 PF05132.9 CDI87699.1 - 1.9 8.5 13.5 1.9 8.4 9.4 1.1 1 0 0 1 1 1 0 RNA polymerase III RPC4 Herpes_DNAp_acc PF04929.7 CDI87699.1 - 1.9 7.3 14.0 1.8 7.4 9.7 1.0 1 0 0 1 1 1 0 Herpes DNA replication accessory factor ARF7EP_C PF14949.1 CDI87699.1 - 2 8.8 15.1 2.4 8.5 10.5 1.2 1 0 0 1 1 1 0 ARF7 effector protein C-terminus Dala_Dala_lig_N PF01820.16 CDI87699.1 - 2.3 8.5 8.4 2.9 8.2 5.8 1.3 1 0 0 1 1 1 0 D-ala D-ala ligase N-terminus Rtf2 PF04641.7 CDI87699.1 - 2.3 7.3 16.6 2.6 7.1 11.5 1.0 1 0 0 1 1 1 0 Rtf2 RING-finger DUF3121 PF11319.3 CDI87699.1 - 2.3 7.6 13.6 2.6 7.5 9.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3121) CKAP2_C PF15297.1 CDI87699.1 - 2.5 6.8 18.3 2.6 6.7 12.7 1.0 1 0 0 1 1 1 0 Cytoskeleton-associated protein 2 C-terminus DUF2370 PF10176.4 CDI87699.1 - 2.6 7.3 12.1 2.6 7.2 8.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) TraH_2 PF06871.6 CDI87699.1 - 2.6 7.4 6.3 2.9 7.2 4.4 1.2 1 0 0 1 1 1 0 TraH_2 Maf1 PF09174.5 CDI87699.1 - 2.6 7.8 10.5 3.1 7.6 7.2 1.0 1 0 0 1 1 1 0 Maf1 regulator Gti1_Pac2 PF09729.4 CDI87699.1 - 2.7 7.8 14.0 2.9 7.7 9.7 1.1 1 0 0 1 1 1 0 Gti1/Pac2 family CPSF100_C PF13299.1 CDI87699.1 - 3.2 7.9 14.8 3.6 7.7 10.3 1.0 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal GAGA_bind PF06217.7 CDI87699.1 - 3.2 7.6 16.6 3.1 7.6 11.5 1.0 1 0 0 1 1 1 0 GAGA binding protein-like family DDRGK PF09756.4 CDI87699.1 - 3.2 7.0 25.6 3.9 6.8 17.8 1.0 1 0 0 1 1 1 0 DDRGK domain FAM176 PF14851.1 CDI87699.1 - 3.4 7.3 11.0 4.1 7.0 7.6 1.1 1 0 0 1 1 1 0 FAM176 family DUF3984 PF13136.1 CDI87699.1 - 3.4 6.8 16.4 3.9 6.6 11.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3984) DUF4589 PF15252.1 CDI87699.1 - 3.5 7.3 14.6 4.1 7.1 10.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4589) DUF2058 PF09831.4 CDI87699.1 - 3.6 7.4 28.9 3.6 7.4 20.0 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2058) EIIBC-GUT_N PF03612.9 CDI87699.1 - 3.7 7.1 14.3 4.8 6.7 9.9 1.2 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Kei1 PF08552.6 CDI87699.1 - 4.2 6.9 11.8 4.5 6.8 8.2 1.1 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 APG6 PF04111.7 CDI87699.1 - 4.3 6.2 21.0 5 6.0 14.6 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 CobT PF06213.7 CDI87699.1 - 4.4 6.3 12.3 4.4 6.3 8.5 1.0 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Plasmodium_Vir PF05795.6 CDI87699.1 - 4.6 6.3 9.1 4.5 6.3 6.3 1.0 1 0 0 1 1 1 0 Plasmodium vivax Vir protein YqfQ PF14181.1 CDI87699.1 - 4.8 7.2 20.6 5.4 7.0 14.3 1.1 1 0 0 1 1 1 0 YqfQ-like protein CagX PF03524.10 CDI87699.1 - 5 6.3 12.3 7 5.8 8.5 1.3 1 0 0 1 1 1 0 Conjugal transfer protein Pex14_N PF04695.8 CDI87699.1 - 5 7.1 23.9 6 6.9 16.6 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF2828 PF11443.3 CDI87699.1 - 5 5.1 14.4 5.8 4.9 10.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) eIF-3_zeta PF05091.7 CDI87699.1 - 5.1 5.5 23.1 5.5 5.4 16.0 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) FAM60A PF15396.1 CDI87699.1 - 5.3 6.7 14.2 6.6 6.4 9.9 1.2 1 0 0 1 1 1 0 Protein Family FAM60A Raftlin PF15250.1 CDI87699.1 - 5.7 5.3 17.6 6.1 5.2 12.2 1.0 1 0 0 1 1 1 0 Raftlin Peptidase_S49_N PF08496.5 CDI87699.1 - 5.7 6.7 18.8 7.8 6.2 13.0 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF523 PF04463.7 CDI87699.1 - 5.9 6.6 8.6 2.9 7.6 3.8 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF523) DUF966 PF06136.8 CDI87699.1 - 6.3 6.1 16.7 7.2 5.9 11.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Bul1_N PF04425.7 CDI87699.1 - 6.8 5.1 17.4 7.7 4.9 12.0 1.0 1 0 0 1 1 1 0 Bul1 N terminus Spore_coat_CotO PF14153.1 CDI87699.1 - 6.9 6.0 24.9 7.8 5.8 17.2 1.1 1 0 0 1 1 1 0 Spore coat protein CotO DUF3306 PF11748.3 CDI87699.1 - 7.3 7.2 14.2 11 6.6 9.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3306) Cellulose_synt PF03552.9 CDI87699.1 - 7.5 4.7 12.3 7.8 4.6 8.6 1.0 1 0 0 1 1 1 0 Cellulose synthase DUF853 PF05872.7 CDI87699.1 - 7.6 4.7 15.0 8 4.6 10.4 1.0 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) DDHD PF02862.12 CDI87699.1 - 7.7 6.2 17.3 8.3 6.1 12.0 1.0 1 0 0 1 1 1 0 DDHD domain Asp-B-Hydro_N PF05279.6 CDI87699.1 - 8.1 6.2 13.3 9.1 6.0 9.2 1.0 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region DUF4011 PF13195.1 CDI87699.1 - 8.1 6.4 10.3 9.5 6.1 7.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4011) BORG_CEP PF14957.1 CDI87699.1 - 8.2 7.3 12.8 9.1 7.2 8.9 1.1 1 0 0 1 1 1 0 Cdc42 effector Adeno_VII PF03228.9 CDI87699.1 - 8.6 6.9 9.6 9.7 6.8 6.7 1.1 1 0 0 1 1 1 0 Adenoviral core protein VII RR_TM4-6 PF06459.7 CDI87699.1 - 9.1 6.0 17.7 10 5.9 12.3 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Aldo_ket_red PF00248.16 CDI87701.1 - 1.3e-08 34.0 0.0 2.1e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 Aldo/keto reductase family PAS_4 PF08448.5 CDI87701.1 - 0.014 15.3 0.1 0.22 11.5 0.0 2.3 1 1 1 2 2 2 0 PAS fold Pkinase PF00069.20 CDI87702.1 - 0.00018 20.7 0.0 0.00018 20.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Transglut_prok PF09017.5 CDI87702.1 - 0.7 8.9 7.4 0.83 8.6 5.1 1.0 1 0 0 1 1 1 0 Microbial transglutaminase RR_TM4-6 PF06459.7 CDI87702.1 - 0.75 9.6 4.4 0.99 9.2 3.0 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CT47 PF15623.1 CDI87702.1 - 0.8 9.3 15.6 0.98 9.1 10.8 1.1 1 0 0 1 1 1 0 Cancer/testis gene family 47 Amidohydro_2 PF04909.9 CDI87702.1 - 3 7.3 6.9 3.5 7.1 4.8 1.1 1 0 0 1 1 1 0 Amidohydrolase Med3 PF11593.3 CDI87702.1 - 6.7 5.8 13.8 7.8 5.6 9.5 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Syntaxin-6_N PF09177.6 CDI87703.1 - 0.019 15.3 6.6 0.067 13.6 0.1 2.8 1 1 1 2 2 2 0 Syntaxin 6, N-terminal UPF0242 PF06785.6 CDI87703.1 - 0.066 11.8 7.4 0.037 12.7 3.7 1.5 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) NHR2 PF08788.6 CDI87703.1 - 0.08 12.4 0.1 0.69 9.4 0.0 2.3 1 1 1 2 2 2 0 NHR2 domain like His_kinase PF06580.8 CDI87703.1 - 0.097 12.6 1.3 0.31 10.9 0.1 2.4 2 2 0 2 2 2 0 Histidine kinase TF_AP-2 PF03299.9 CDI87703.1 - 0.12 11.9 3.6 0.14 11.6 2.5 1.3 1 0 0 1 1 1 0 Transcription factor AP-2 Bacillus_HBL PF05791.6 CDI87703.1 - 0.87 8.9 5.1 3 7.1 0.1 2.4 1 1 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) TPR_MLP1_2 PF07926.7 CDI87703.1 - 1.5 8.5 13.3 0.61 9.8 4.6 2.3 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein SlyX PF04102.7 CDI87703.1 - 1.6 9.1 5.5 2.5 8.5 1.0 2.6 1 1 1 2 2 2 0 SlyX TMF_DNA_bd PF12329.3 CDI87703.1 - 1.8 8.3 19.4 0.079 12.7 2.0 3.1 2 1 0 3 3 3 0 TATA element modulatory factor 1 DNA binding DUF972 PF06156.8 CDI87703.1 - 2 8.8 11.6 2.7 8.3 0.6 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF972) MutS_III PF05192.13 CDI87703.1 - 2.2 8.0 8.7 0.39 10.4 0.8 2.1 1 1 1 2 2 2 0 MutS domain III TMF_TATA_bd PF12325.3 CDI87703.1 - 2.6 7.8 12.9 2.2 8.0 2.8 2.5 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding Seryl_tRNA_N PF02403.17 CDI87703.1 - 3.1 7.8 13.4 5.2 7.1 1.3 2.4 1 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DALR_2 PF09190.6 CDI87703.1 - 3.2 8.0 5.7 1 9.6 0.2 2.6 2 1 1 3 3 3 0 DALR domain ATG16 PF08614.6 CDI87703.1 - 3.9 7.2 14.0 24 4.6 9.6 1.9 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) V_ATPase_I PF01496.14 CDI87703.1 - 8.7 4.0 10.7 13 3.4 4.6 1.9 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family Filament PF00038.16 CDI87704.1 - 0.0067 15.9 2.1 0.01 15.3 1.5 1.3 1 0 0 1 1 1 1 Intermediate filament protein BBIP10 PF14777.1 CDI87704.1 - 0.033 13.5 0.5 0.092 12.1 0.3 1.7 1 0 0 1 1 1 0 Cilia BBSome complex subunit 10 DUF740 PF05340.7 CDI87705.1 - 1 7.6 7.9 1.2 7.3 5.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF740) Rtf2 PF04641.7 CDI87705.1 - 1.8 7.7 21.3 1.9 7.6 14.8 1.0 1 0 0 1 1 1 0 Rtf2 RING-finger BCAS3 PF12490.3 CDI87705.1 - 3.6 6.8 19.1 3.8 6.7 13.2 1.0 1 0 0 1 1 1 0 Breast carcinoma amplified sequence 3 FYDLN_acid PF09538.5 CDI87705.1 - 4.1 8.0 8.3 5.5 7.6 5.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) G6PD_N PF00479.17 CDI87705.1 - 5.6 7.1 14.9 6.7 6.9 10.3 1.0 1 0 0 1 1 1 0 Glucose-6-phosphate dehydrogenase, NAD binding domain DUF3499 PF12005.3 CDI87705.1 - 6.1 7.0 9.9 7.6 6.7 6.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3499) DUF2370 PF10176.4 CDI87705.1 - 7 5.9 15.2 7.6 5.7 10.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) L31 PF09784.4 CDI87705.1 - 7.3 6.7 15.1 9.2 6.3 10.5 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L31 DDRGK PF09756.4 CDI87705.1 - 8.8 5.6 28.9 10 5.4 20.0 1.0 1 0 0 1 1 1 0 DDRGK domain DUF4045 PF13254.1 CDI87705.1 - 9.7 5.3 18.3 10 5.2 12.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) DUF2227 PF09988.4 CDI87708.1 - 0.23 11.0 5.8 0.25 10.9 4.0 1.0 1 0 0 1 1 1 0 Uncharacterized metal-binding protein (DUF2227) Rhabdo_NV PF02484.10 CDI87708.1 - 0.3 10.9 1.5 0.3 10.9 1.0 1.2 1 0 0 1 1 1 0 Rhabdovirus Non-virion protein CobU PF02283.11 CDI87708.1 - 0.45 9.9 5.0 0.47 9.8 3.4 1.1 1 0 0 1 1 1 0 Cobinamide kinase / cobinamide phosphate guanyltransferase Cache_3 PF14827.1 CDI87708.1 - 0.88 9.4 8.5 0.97 9.3 5.9 1.1 1 0 0 1 1 1 0 Sensory domain of two-component sensor kinase DUF4512 PF14975.1 CDI87708.1 - 1.8 9.4 8.8 2 9.2 6.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4512) Lipoprotein_X PF03305.8 CDI87708.1 - 3 7.1 15.0 3.3 7.0 10.4 1.0 1 0 0 1 1 1 0 Mycoplasma MG185/MG260 protein Rtf2 PF04641.7 CDI87708.1 - 3.2 6.8 15.1 3.6 6.7 10.4 1.0 1 0 0 1 1 1 0 Rtf2 RING-finger DUF2899 PF11449.3 CDI87708.1 - 5.3 6.1 5.9 5.9 5.9 4.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2899) ExbD PF02472.11 CDI87708.1 - 7.1 6.6 13.6 7.8 6.5 9.4 1.0 1 0 0 1 1 1 0 Biopolymer transport protein ExbD/TolR GRP PF07172.6 CDI87708.1 - 8 7.0 8.9 1.1 9.7 3.2 1.6 1 1 1 2 2 2 0 Glycine rich protein family FHIPEP PF00771.15 CDI87708.1 - 8.2 4.6 16.0 8.6 4.5 11.1 1.0 1 0 0 1 1 1 0 FHIPEP family CD20 PF04103.10 CDI87709.1 - 0.014 15.2 1.5 0.016 15.1 1.0 1.1 1 0 0 1 1 1 0 CD20-like family DUF4366 PF14283.1 CDI87709.1 - 0.015 14.7 1.8 0.016 14.5 1.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) Trp_oprn_chp PF09534.5 CDI87709.1 - 0.022 14.3 5.8 0.024 14.2 4.0 1.0 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF2217 PF10265.4 CDI87709.1 - 0.041 12.6 6.1 0.047 12.4 4.2 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) CPSF73-100_C PF11718.3 CDI87709.1 - 0.046 13.0 4.2 0.054 12.8 2.9 1.0 1 0 0 1 1 1 0 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term OATP PF03137.15 CDI87709.1 - 0.05 11.6 5.1 0.05 11.6 3.5 1.0 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family DUF3824 PF12868.2 CDI87709.1 - 0.051 14.4 7.0 0.062 14.2 4.9 1.2 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) AIF_C PF14721.1 CDI87709.1 - 0.064 13.5 8.3 0.069 13.3 5.7 1.0 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term DUF533 PF04391.7 CDI87709.1 - 0.066 12.5 15.4 0.075 12.4 10.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF533) Tom22 PF04281.8 CDI87709.1 - 0.078 12.5 3.8 0.091 12.2 2.6 1.2 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 NPR3 PF03666.8 CDI87709.1 - 0.096 11.2 6.3 0.097 11.1 4.4 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 HA2 PF04408.18 CDI87709.1 - 0.099 12.6 4.7 0.13 12.3 3.3 1.2 1 0 0 1 1 1 0 Helicase associated domain (HA2) Shadoo PF14999.1 CDI87709.1 - 0.099 12.5 1.0 0.099 12.4 0.7 1.1 1 0 0 1 1 1 0 Shadow of prion protein, neuroprotective Glyco_hydro_9 PF00759.14 CDI87709.1 - 0.099 11.5 8.9 0.11 11.4 6.2 1.0 1 0 0 1 1 1 0 Glycosyl hydrolase family 9 Pex14_N PF04695.8 CDI87709.1 - 0.1 12.6 15.5 0.12 12.4 10.7 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region CoA_transf_3 PF02515.12 CDI87709.1 - 0.11 11.7 7.2 0.13 11.4 5.0 1.2 1 0 0 1 1 1 0 CoA-transferase family III DUF912 PF06024.7 CDI87709.1 - 0.12 12.4 2.5 0.12 12.4 1.7 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) FimP PF09766.4 CDI87709.1 - 0.13 11.2 18.2 0.14 11.2 12.6 1.0 1 0 0 1 1 1 0 Fms-interacting protein DUF3357 PF11837.3 CDI87709.1 - 0.15 11.9 2.5 0.35 10.7 1.8 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF3357) Cytochrom_C_asm PF01578.15 CDI87709.1 - 0.16 11.5 0.2 0.19 11.2 0.2 1.1 1 0 0 1 1 1 0 Cytochrome C assembly protein Zip PF02535.17 CDI87709.1 - 0.16 10.9 3.2 0.17 10.8 2.2 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Ctr PF04145.10 CDI87709.1 - 0.25 11.3 7.2 0.26 11.3 5.0 1.1 1 0 0 1 1 1 0 Ctr copper transporter family Peptidase_S49_N PF08496.5 CDI87709.1 - 0.27 11.0 7.5 0.28 10.9 5.2 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF4175 PF13779.1 CDI87709.1 - 0.27 8.8 27.2 0.29 8.8 18.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Glt_symporter PF03616.9 CDI87709.1 - 0.28 9.6 2.1 0.28 9.6 1.5 1.1 1 0 0 1 1 1 0 Sodium/glutamate symporter R_equi_Vir PF05526.6 CDI87709.1 - 0.31 10.6 7.5 0.31 10.6 5.2 1.0 1 0 0 1 1 1 0 Rhodococcus equi virulence-associated protein FAM60A PF15396.1 CDI87709.1 - 0.37 10.4 5.9 0.39 10.4 4.1 1.1 1 0 0 1 1 1 0 Protein Family FAM60A DUF2782 PF11191.3 CDI87709.1 - 0.43 10.5 7.1 0.55 10.2 4.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2782) Tetraspannin PF00335.15 CDI87709.1 - 0.45 9.7 4.8 0.51 9.5 3.3 1.0 1 0 0 1 1 1 0 Tetraspanin family ATAD4 PF15321.1 CDI87709.1 - 0.49 11.4 7.5 0.58 11.1 5.2 1.2 1 0 0 1 1 1 0 ATPase family AAA domain containing 4 FHIPEP PF00771.15 CDI87709.1 - 0.51 8.6 8.4 0.55 8.4 5.8 1.0 1 0 0 1 1 1 0 FHIPEP family HemX PF04375.9 CDI87709.1 - 0.56 8.7 23.4 0.61 8.6 16.2 1.0 1 0 0 1 1 1 0 HemX IncA PF04156.9 CDI87709.1 - 0.6 9.6 15.0 0.78 9.3 10.4 1.2 1 0 0 1 1 1 0 IncA protein Suf PF05843.9 CDI87709.1 - 0.6 9.7 14.4 0.62 9.7 10.0 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Sulfotransfer_2 PF03567.9 CDI87709.1 - 0.63 9.6 7.9 0.71 9.5 5.4 1.0 1 0 0 1 1 1 0 Sulfotransferase family SelP_N PF04592.9 CDI87709.1 - 0.65 9.3 11.5 0.64 9.3 8.0 1.0 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Baculo_PP31 PF05311.6 CDI87709.1 - 0.66 9.1 12.0 0.68 9.1 8.3 1.0 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) RskA PF10099.4 CDI87709.1 - 0.67 9.6 17.9 1.2 8.8 12.4 1.5 1 1 0 1 1 1 0 Anti-sigma-K factor rskA FAM176 PF14851.1 CDI87709.1 - 0.67 9.6 3.2 0.73 9.5 2.2 1.1 1 0 0 1 1 1 0 FAM176 family ADP_ribosyl_GH PF03747.9 CDI87709.1 - 0.7 9.6 3.9 0.72 9.5 2.7 1.1 1 0 0 1 1 1 0 ADP-ribosylglycohydrolase Dala_Dala_lig_N PF01820.16 CDI87709.1 - 0.7 10.2 3.6 0.68 10.2 2.5 1.1 1 0 0 1 1 1 0 D-ala D-ala ligase N-terminus DUF3675 PF12428.3 CDI87709.1 - 0.72 10.1 5.4 0.76 10.0 3.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3675) Folate_carrier PF01770.13 CDI87709.1 - 0.75 8.2 7.3 0.78 8.1 5.0 1.0 1 0 0 1 1 1 0 Reduced folate carrier Apc1 PF12859.2 CDI87709.1 - 0.75 10.0 4.5 0.83 9.8 3.1 1.1 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 1 Serinc PF03348.10 CDI87709.1 - 0.88 8.2 11.9 0.86 8.2 8.3 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) DUF4259 PF14078.1 CDI87709.1 - 0.99 9.9 4.9 1.2 9.6 3.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4259) MelC1 PF06236.6 CDI87709.1 - 1.1 9.2 6.6 1.5 8.7 4.6 1.3 1 0 0 1 1 1 0 Tyrosinase co-factor MelC1 Prog_receptor PF02161.10 CDI87709.1 - 1.2 7.8 9.8 1.3 7.7 6.8 1.0 1 0 0 1 1 1 0 Progesterone receptor Kei1 PF08552.6 CDI87709.1 - 1.2 8.7 8.8 1.3 8.6 6.1 1.1 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 DUF1764 PF08576.5 CDI87709.1 - 1.2 9.8 12.9 1.4 9.7 9.0 1.1 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) EphA2_TM PF14575.1 CDI87709.1 - 1.3 9.5 10.3 11 6.4 7.1 2.0 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Gag_spuma PF03276.9 CDI87709.1 - 1.6 6.9 21.8 1.7 6.9 15.1 1.0 1 0 0 1 1 1 0 Spumavirus gag protein DDRGK PF09756.4 CDI87709.1 - 1.7 8.0 16.0 1.9 7.8 11.1 1.1 1 0 0 1 1 1 0 DDRGK domain RED_N PF07808.8 CDI87709.1 - 2.1 7.4 15.2 2.4 7.2 10.6 1.1 1 0 0 1 1 1 0 RED-like protein N-terminal region Carboxyl_trans PF01039.17 CDI87709.1 - 2.2 6.5 7.9 2.2 6.5 5.5 1.0 1 0 0 1 1 1 0 Carboxyl transferase domain Chorion_2 PF03964.10 CDI87709.1 - 2.2 8.8 8.7 3.2 8.3 6.1 1.3 1 0 0 1 1 1 0 Chorion family 2 Peptidase_U57 PF05582.7 CDI87709.1 - 2.2 7.1 9.5 2.4 7.0 6.6 1.0 1 0 0 1 1 1 0 YabG peptidase U57 Rtf2 PF04641.7 CDI87709.1 - 2.2 7.3 10.8 2.2 7.3 7.5 1.0 1 0 0 1 1 1 0 Rtf2 RING-finger DUF2232 PF09991.4 CDI87709.1 - 2.4 7.0 5.8 2.4 7.1 4.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) Fungal_trans_2 PF11951.3 CDI87709.1 - 2.7 6.4 9.1 2.7 6.4 6.3 1.1 1 0 0 1 1 1 0 Fungal specific transcription factor domain DDHD PF02862.12 CDI87709.1 - 2.9 7.6 9.5 2.8 7.6 6.6 1.0 1 0 0 1 1 1 0 DDHD domain FLO_LFY PF01698.11 CDI87709.1 - 2.9 6.6 12.1 3.1 6.5 8.4 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein MDFI PF15316.1 CDI87709.1 - 3 7.8 6.1 2.9 7.8 4.2 1.1 1 0 0 1 1 1 0 MyoD family inhibitor Kinesin PF00225.18 CDI87709.1 - 3 6.4 10.2 3.6 6.2 7.0 1.0 1 0 0 1 1 1 0 Kinesin motor domain DUF3450 PF11932.3 CDI87709.1 - 3.1 7.0 25.9 3.3 6.8 17.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF3464 PF11947.3 CDI87709.1 - 3.1 7.2 8.5 3.4 7.1 5.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) Band_3_cyto PF07565.8 CDI87709.1 - 3.2 7.1 10.7 3.3 7.1 7.4 1.0 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Oleosin PF01277.12 CDI87709.1 - 3.4 7.2 7.0 4.1 6.9 4.9 1.2 1 0 0 1 1 1 0 Oleosin PBP1_TM PF14812.1 CDI87709.1 - 3.7 7.9 7.8 4.7 7.5 5.4 1.1 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Hid1 PF12722.2 CDI87709.1 - 3.7 5.0 9.8 3.7 5.0 6.8 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Neur_chan_memb PF02932.11 CDI87709.1 - 3.8 7.3 6.9 3.8 7.3 4.8 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF2946 PF11162.3 CDI87709.1 - 4.6 7.4 11.2 5.3 7.2 7.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2946) DUF3984 PF13136.1 CDI87709.1 - 5.2 6.1 10.9 5.8 6.0 7.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3984) SprA-related PF12118.3 CDI87709.1 - 5.3 6.2 31.6 6.2 6.0 21.9 1.1 1 0 0 1 1 1 0 SprA-related family BTV_NS2 PF04514.7 CDI87709.1 - 5.5 5.7 8.9 5.5 5.7 6.1 1.0 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 TCP PF03634.8 CDI87709.1 - 6.3 7.1 15.2 7 7.0 10.6 1.1 1 0 0 1 1 1 0 TCP family transcription factor Med19 PF10278.4 CDI87709.1 - 6.7 6.3 9.1 7.7 6.1 6.3 1.1 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 Spore_coat_CotO PF14153.1 CDI87709.1 - 6.8 6.0 17.8 7 6.0 12.4 1.0 1 0 0 1 1 1 0 Spore coat protein CotO DUF1980 PF09323.5 CDI87709.1 - 6.8 6.3 8.9 7.2 6.3 6.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) PXA PF02194.10 CDI87709.1 - 6.8 6.2 8.9 6.9 6.1 6.2 1.0 1 0 0 1 1 1 0 PXA domain Helicase_RecD PF05127.9 CDI87709.1 - 6.9 6.2 8.7 7.4 6.1 6.1 1.1 1 0 0 1 1 1 0 Helicase DUF3371 PF11851.3 CDI87709.1 - 7 7.3 15.1 8.9 7.0 10.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3371) Spc7_N PF15402.1 CDI87709.1 - 7.3 4.4 14.3 8.3 4.2 9.9 1.0 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 NusB PF01029.13 CDI87709.1 - 8.5 6.3 7.8 11 6.0 5.4 1.1 1 0 0 1 1 1 0 NusB family DUF775 PF05603.7 CDI87709.1 - 9.1 5.7 12.9 11 5.5 9.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF775) RR_TM4-6 PF06459.7 CDI87709.1 - 9.4 6.0 11.3 9.5 6.0 7.8 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 RIC3 PF15361.1 CDI87709.1 - 9.6 6.4 13.3 11 6.2 9.3 1.1 1 0 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 DcuA_DcuB PF03605.9 CDI87710.1 - 0.00021 20.2 0.3 0.00023 20.1 0.2 1.0 1 0 0 1 1 1 1 Anaerobic c4-dicarboxylate membrane transporter Pro-rich PF15240.1 CDI87710.1 - 0.001 19.2 11.0 0.0014 18.7 7.6 1.2 1 0 0 1 1 1 1 Proline-rich DUF2615 PF11027.3 CDI87710.1 - 0.0076 16.1 1.1 0.012 15.4 0.6 1.6 1 1 1 2 2 2 1 Protein of unknown function (DUF2615) Cas1_AcylT PF07779.7 CDI87710.1 - 0.021 13.2 0.0 0.027 12.9 0.0 1.1 1 0 0 1 1 1 0 10 TM Acyl Transferase domain found in Cas1p DUF1345 PF07077.6 CDI87710.1 - 0.059 12.8 1.8 0.095 12.2 0.9 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1345) DUF4271 PF14093.1 CDI87710.1 - 0.098 12.3 0.1 0.12 12.0 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4271) ABC2_membrane_2 PF12679.2 CDI87710.1 - 0.1 11.4 1.5 0.13 11.0 1.0 1.3 1 0 0 1 1 1 0 ABC-2 family transporter protein RskA PF10099.4 CDI87710.1 - 0.16 11.7 7.1 0.27 10.9 4.8 1.5 1 1 1 2 2 2 0 Anti-sigma-K factor rskA TFIIA PF03153.8 CDI87710.1 - 0.18 11.6 8.2 0.2 11.5 5.7 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit 60KD_IMP PF02096.15 CDI87710.1 - 0.2 11.3 8.6 0.31 10.6 5.9 1.4 1 1 0 1 1 1 0 60Kd inner membrane protein SbcCD_C PF13558.1 CDI87710.1 - 0.2 11.5 2.1 0.3 11.0 0.2 2.0 1 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit 7TM_GPCR_Srv PF10323.4 CDI87710.1 - 0.21 10.6 1.3 0.22 10.5 0.9 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srv DUF912 PF06024.7 CDI87710.1 - 0.27 11.3 3.5 0.22 11.5 0.9 1.9 1 1 1 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF3365 PF11845.3 CDI87710.1 - 0.69 9.7 5.2 1.4 8.7 3.6 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3365) DUF3357 PF11837.3 CDI87710.1 - 0.85 9.4 4.8 0.23 11.2 0.4 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF3357) PKI PF02827.11 CDI87710.1 - 1.1 9.4 3.3 0.62 10.2 0.9 1.5 2 0 0 2 2 2 0 cAMP-dependent protein kinase inhibitor Gastrin PF00918.12 CDI87710.1 - 1.5 9.6 8.6 2.4 8.9 6.0 1.2 1 0 0 1 1 1 0 Gastrin/cholecystokinin family DUF2075 PF09848.4 CDI87710.1 - 2.1 7.2 7.7 2.5 7.0 5.3 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) DUF243 PF03103.12 CDI87710.1 - 3.4 7.8 11.8 0.61 10.2 2.9 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF243) Sex_peptide PF08138.6 CDI87710.1 - 3.8 7.4 8.7 7 6.5 3.8 2.8 1 1 1 2 2 2 0 Sex peptide (SP) family DOR PF14839.1 CDI87710.1 - 4.3 7.0 8.9 5.1 6.7 6.2 1.1 1 0 0 1 1 1 0 DOR family Prothymosin PF03247.9 CDI87711.1 - 0.23 11.5 5.1 0.29 11.2 3.6 1.1 1 0 0 1 1 1 0 Prothymosin/parathymosin family 2OG-FeII_Oxy_5 PF13759.1 CDI87711.1 - 0.36 11.1 5.0 0.47 10.7 3.5 1.2 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase DUF2407 PF10302.4 CDI87711.1 - 2.4 8.4 5.2 2.8 8.1 3.6 1.1 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain DUF775 PF05603.7 CDI87711.1 - 5.5 6.4 13.2 6.6 6.2 9.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF775) TORC_M PF12885.2 CDI87711.1 - 6.7 6.4 11.7 7.8 6.2 8.1 1.1 1 0 0 1 1 1 0 Transducer of regulated CREB activity middle domain RED_N PF07808.8 CDI87711.1 - 7 5.7 15.7 8.4 5.5 10.9 1.1 1 0 0 1 1 1 0 RED-like protein N-terminal region SLD3 PF08639.5 CDI87711.1 - 9.4 4.7 16.5 10 4.6 11.4 1.0 1 0 0 1 1 1 0 DNA replication regulator SLD3 Zein PF01559.11 CDI87712.1 - 0.0071 15.6 17.5 0.087 12.0 12.1 1.9 1 1 0 1 1 1 1 Zein seed storage protein WSC PF01822.14 CDI87712.1 - 0.44 10.4 11.7 1.2 9.0 8.1 1.6 1 1 0 1 1 1 0 WSC domain I_LWEQ PF01608.12 CDI87712.1 - 2.7 7.9 14.3 2.8 7.8 9.9 1.0 1 0 0 1 1 1 0 I/LWEQ domain BAF1_ABF1 PF04684.8 CDI87712.1 - 4.4 6.0 7.5 5.2 5.7 5.2 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor HlyD PF00529.15 CDI87712.1 - 9.4 5.4 11.1 11 5.2 7.7 1.1 1 0 0 1 1 1 0 HlyD family secretion protein Sec23_helical PF04815.10 CDI87713.1 - 3.6e-32 109.8 1.0 6.4e-32 109.0 0.7 1.4 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_trunk PF04811.10 CDI87713.1 - 2.7e-20 72.8 0.1 4.3e-20 72.1 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.7 CDI87713.1 - 4.4e-18 65.5 0.1 1.3e-16 60.8 0.0 2.4 2 0 0 2 2 2 1 Sec23/Sec24 beta-sandwich domain TPR_11 PF13414.1 CDI87714.1 - 2.1e-30 104.1 2.0 7.5e-21 73.5 0.1 2.2 2 0 0 2 2 2 2 TPR repeat TPR_1 PF00515.23 CDI87714.1 - 1.2e-22 78.4 1.5 1.9e-07 30.4 0.0 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 CDI87714.1 - 4.2e-21 73.1 0.8 3.7e-06 26.4 0.0 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.1 CDI87714.1 - 5.7e-16 57.0 0.8 0.00042 19.9 0.0 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_17 PF13431.1 CDI87714.1 - 4.7e-13 48.2 0.8 0.0006 19.8 0.0 4.4 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.1 CDI87714.1 - 7e-13 47.9 0.6 0.0011 19.4 0.4 3.9 2 1 2 4 4 3 3 Tetratricopeptide repeat TPR_16 PF13432.1 CDI87714.1 - 2.7e-12 47.0 0.7 4.5e-06 27.1 0.0 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 CDI87714.1 - 1e-09 38.1 0.1 8.2e-06 25.6 0.1 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.1 CDI87714.1 - 3.7e-09 36.7 1.5 0.00017 21.8 0.0 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.1 CDI87714.1 - 1.2e-08 34.6 0.2 2.2e-05 24.2 0.1 2.9 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 CDI87714.1 - 8.7e-08 31.4 0.1 0.011 15.5 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.1 CDI87714.1 - 0.00072 19.8 3.3 0.65 10.5 0.0 4.5 4 1 0 4 4 4 1 Tetratricopeptide repeat NARP1 PF12569.3 CDI87714.1 - 0.0019 17.0 0.5 0.003 16.4 0.4 1.4 1 0 0 1 1 1 1 NMDA receptor-regulated protein 1 Apc3 PF12895.2 CDI87714.1 - 0.003 17.6 0.5 0.012 15.6 0.1 2.2 1 1 1 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 SHNi-TPR PF10516.4 CDI87714.1 - 0.0082 15.3 0.1 5 6.4 0.0 2.6 2 0 0 2 2 2 2 SHNi-TPR TPR_20 PF14561.1 CDI87714.1 - 0.0087 16.1 1.1 0.48 10.5 0.0 2.9 2 2 1 3 3 3 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 CDI87714.1 - 0.0088 15.9 0.6 0.48 10.3 0.0 3.0 4 1 0 4 4 3 1 Fis1 C-terminal tetratricopeptide repeat MAS20 PF02064.10 CDI87714.1 - 0.038 13.8 0.3 0.32 10.9 0.0 2.2 2 1 0 2 2 2 0 MAS20 protein import receptor DUF3856 PF12968.2 CDI87714.1 - 0.081 12.7 0.9 0.62 9.8 0.2 2.4 1 1 0 1 1 1 0 Domain of Unknown Function (DUF3856) HemY_N PF07219.8 CDI87714.1 - 1.1 8.8 3.2 2.3 7.7 0.0 2.3 3 0 0 3 3 3 0 HemY protein N-terminus Herpes_env PF01673.13 CDI87715.1 - 0.056 12.0 3.9 0.071 11.6 2.7 1.1 1 0 0 1 1 1 0 Herpesvirus putative major envelope glycoprotein ACDC PF14733.1 CDI87715.1 - 0.11 12.5 0.0 0.21 11.7 0.0 1.4 1 0 0 1 1 1 0 AP2-coincident C-terminal CRAL_TRIO PF00650.15 CDI87717.1 - 1.2e-06 28.0 0.0 4e-06 26.4 0.0 1.7 2 0 0 2 2 2 1 CRAL/TRIO domain Peptidase_S49_N PF08496.5 CDI87718.1 - 0.056 13.2 0.1 0.27 11.0 0.2 2.0 2 0 0 2 2 2 0 Peptidase family S49 N-terminal DUF1162 PF06650.7 CDI87721.1 - 1.5e-07 30.9 7.2 7.9e-05 21.9 0.0 3.5 2 1 1 3 3 3 2 Protein of unknown function (DUF1162) TFIIA PF03153.8 CDI87721.1 - 0.4 10.5 36.8 0.1 12.4 16.6 3.2 3 0 0 3 3 3 0 Transcription factor IIA, alpha/beta subunit Draxin PF15550.1 CDI87721.1 - 2.8 7.4 13.6 6.1 6.4 9.4 1.5 1 0 0 1 1 1 0 Draxin DUF4551 PF15087.1 CDI87721.1 - 4.2 5.6 12.4 7.3 4.8 8.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Hid1 PF12722.2 CDI87722.1 - 0.26 8.9 24.4 0.41 8.2 16.9 1.5 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Asp-B-Hydro_N PF05279.6 CDI87722.1 - 2.6 7.8 24.3 3.9 7.2 16.8 1.4 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region DUF1510 PF07423.6 CDI87722.1 - 9 5.6 32.3 18 4.6 22.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Ribosomal_60s PF00428.14 CDI87723.1 - 0.01 16.2 12.2 0.01 16.2 8.4 4.3 2 1 2 4 4 4 0 60s Acidic ribosomal protein AAA_23 PF13476.1 CDI87723.1 - 1.8 8.8 19.5 3.9 7.7 13.5 1.5 1 0 0 1 1 1 0 AAA domain Epimerase_Csub PF13950.1 CDI87724.1 - 1.3e-26 92.3 0.1 2.1e-26 91.6 0.0 1.3 1 0 0 1 1 1 1 UDP-glucose 4-epimerase C-term subunit Epimerase PF01370.16 CDI87724.1 - 2.6e-23 82.7 0.1 4.4e-21 75.3 0.0 2.1 1 1 1 2 2 2 2 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 CDI87724.1 - 5.1e-11 41.8 0.0 7.3e-11 41.2 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 CDI87724.1 - 4.4e-10 38.9 0.0 1.5e-09 37.2 0.0 1.7 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein adh_short PF00106.20 CDI87724.1 - 1.2e-06 28.5 0.1 1.8e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase RmlD_sub_bind PF04321.12 CDI87724.1 - 1.3e-06 27.5 0.0 2e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain KR PF08659.5 CDI87724.1 - 2.2e-05 24.1 0.0 3.2e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 KR domain UDPG_MGDP_dh_N PF03721.9 CDI87724.1 - 0.006 15.9 0.2 0.012 15.0 0.2 1.5 1 1 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3HCDH_N PF02737.13 CDI87724.1 - 0.0077 15.9 0.0 0.012 15.2 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 CDI87724.1 - 0.028 14.4 0.0 0.043 13.8 0.0 1.3 1 0 0 1 1 1 0 NADH(P)-binding NAD_binding_4 PF07993.7 CDI87724.1 - 0.035 13.0 0.3 0.3 9.9 0.2 2.0 1 1 0 1 1 1 0 Male sterility protein NmrA PF05368.8 CDI87724.1 - 0.12 11.5 0.1 0.28 10.3 0.0 1.6 2 0 0 2 2 2 0 NmrA-like family NAD_binding_2 PF03446.10 CDI87724.1 - 0.15 11.9 0.0 0.24 11.1 0.0 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Med15 PF09606.5 CDI87728.1 - 0.003 15.8 5.2 0.003 15.8 3.6 2.7 3 0 0 3 3 3 1 ARC105 or Med15 subunit of Mediator complex non-fungal Ctr PF04145.10 CDI87728.1 - 0.016 15.2 3.4 0.61 10.1 0.8 2.6 2 0 0 2 2 2 0 Ctr copper transporter family Spt20 PF12090.3 CDI87728.1 - 0.087 12.1 0.1 0.087 12.1 0.0 2.7 3 1 0 3 3 3 0 Spt20 family DUF3123 PF11321.3 CDI87728.1 - 0.31 11.3 5.1 1 9.6 2.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3123) Folate_carrier PF01770.13 CDI87728.1 - 0.78 8.1 2.6 13 4.1 0.0 2.1 2 0 0 2 2 2 0 Reduced folate carrier Phostensin_N PF13916.1 CDI87728.1 - 4.5 7.3 14.4 2.6 8.0 4.4 2.6 2 0 0 2 2 2 0 PP1-regulatory protein, Phostensin N-terminal RAB3GAP2_N PF14655.1 CDI87728.1 - 6 5.7 8.3 0.44 9.5 1.9 1.8 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus FAM176 PF14851.1 CDI87728.1 - 9.1 5.9 8.6 25 4.5 0.0 2.3 2 0 0 2 2 2 0 FAM176 family Rad10 PF03834.9 CDI87731.1 - 4.1e-19 68.0 0.0 8.4e-19 67.0 0.0 1.5 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) HHH PF00633.18 CDI87731.1 - 5.4e-05 22.6 0.0 0.00015 21.2 0.0 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_2 PF12826.2 CDI87731.1 - 0.0021 17.8 0.0 0.0066 16.3 0.0 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix motif CDC45 PF02724.9 CDI87731.1 - 0.01 13.9 0.5 0.012 13.7 0.4 1.1 1 0 0 1 1 1 0 CDC45-like protein Tfb4 PF03850.9 CDI87731.1 - 0.027 13.7 0.1 0.04 13.1 0.1 1.3 1 0 0 1 1 1 0 Transcription factor Tfb4 Ndc1_Nup PF09531.5 CDI87731.1 - 0.16 10.3 7.5 0.23 9.8 5.2 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup RR_TM4-6 PF06459.7 CDI87731.1 - 0.33 10.8 17.3 0.59 9.9 12.0 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Tim54 PF11711.3 CDI87731.1 - 1.2 7.6 10.0 2.2 6.8 6.9 1.4 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Peptidase_S49_N PF08496.5 CDI87731.1 - 1.5 8.5 6.2 3.5 7.4 4.3 1.6 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Neur_chan_memb PF02932.11 CDI87731.1 - 8.3 6.2 10.5 15 5.3 7.3 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Glycolytic PF00274.14 CDI87732.1 - 7.8e-168 557.2 0.0 8.8e-168 557.1 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-I SR-25 PF10500.4 CDI87733.1 - 7.7e-06 25.5 8.3 8.9e-06 25.3 5.8 1.0 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Suf PF05843.9 CDI87733.1 - 0.0037 17.0 16.5 0.0042 16.8 11.5 1.0 1 0 0 1 1 1 1 Suppressor of forked protein (Suf) OmpH PF03938.9 CDI87733.1 - 0.0049 16.8 18.6 0.0051 16.7 12.9 1.1 1 0 0 1 1 1 1 Outer membrane protein (OmpH-like) Med15 PF09606.5 CDI87733.1 - 0.0074 14.5 28.5 0.0076 14.5 19.8 1.0 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal Pex14_N PF04695.8 CDI87733.1 - 0.0077 16.2 18.0 0.01 15.8 12.5 1.3 1 0 0 1 1 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region CAF-1_p150 PF11600.3 CDI87733.1 - 0.015 14.7 14.6 0.017 14.4 10.1 1.0 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Adaptin_binding PF10199.4 CDI87733.1 - 0.037 14.3 10.9 0.042 14.1 7.6 1.1 1 0 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 Nop53 PF07767.6 CDI87733.1 - 0.037 13.0 11.7 0.044 12.7 8.1 1.0 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) CEP19 PF14933.1 CDI87733.1 - 0.041 14.1 5.4 0.052 13.8 3.7 1.1 1 0 0 1 1 1 0 CEP19-like protein SGT1 PF07093.6 CDI87733.1 - 0.043 12.1 7.6 0.052 11.9 5.2 1.2 1 0 0 1 1 1 0 SGT1 protein FimP PF09766.4 CDI87733.1 - 0.044 12.8 17.5 0.05 12.6 12.1 1.1 1 0 0 1 1 1 0 Fms-interacting protein PRCC PF10253.4 CDI87733.1 - 0.048 14.3 15.0 0.053 14.2 10.4 1.1 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting DUF393 PF04134.7 CDI87733.1 - 0.049 14.7 0.7 0.061 14.4 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF393 His_Phos_2 PF00328.17 CDI87733.1 - 0.058 12.7 4.3 0.066 12.5 3.0 1.0 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 2) Tim54 PF11711.3 CDI87733.1 - 0.064 11.8 7.6 0.074 11.6 5.3 1.0 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DUF1777 PF08648.7 CDI87733.1 - 0.067 12.9 5.0 0.078 12.7 3.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) DUF737 PF05300.6 CDI87733.1 - 0.078 12.9 14.6 0.096 12.6 10.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF737) DUF2126 PF09899.4 CDI87733.1 - 0.079 10.9 7.1 0.087 10.8 4.9 1.0 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) DUF4613 PF15390.1 CDI87733.1 - 0.086 10.9 11.7 0.1 10.7 8.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) DUF4175 PF13779.1 CDI87733.1 - 0.089 10.4 23.2 0.095 10.3 16.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) PGA_cap PF09587.5 CDI87733.1 - 0.096 12.0 2.0 0.1 11.8 1.4 1.0 1 0 0 1 1 1 0 Bacterial capsule synthesis protein PGA_cap Hamartin PF04388.7 CDI87733.1 - 0.1 11.2 12.1 0.12 11.0 8.4 1.0 1 0 0 1 1 1 0 Hamartin protein RP-C_C PF11800.3 CDI87733.1 - 0.11 12.2 9.7 0.12 12.0 6.7 1.1 1 0 0 1 1 1 0 Replication protein C C-terminal region DnaJ-X PF14308.1 CDI87733.1 - 0.12 11.6 11.1 0.14 11.3 7.7 1.2 1 0 0 1 1 1 0 X-domain of DnaJ-containing Dala_Dala_lig_N PF01820.16 CDI87733.1 - 0.12 12.7 3.6 0.15 12.4 2.5 1.2 1 0 0 1 1 1 0 D-ala D-ala ligase N-terminus Peptidase_C58 PF03543.9 CDI87733.1 - 0.13 11.7 12.8 0.14 11.6 8.9 1.1 1 0 0 1 1 1 0 Yersinia/Haemophilus virulence surface antigen GvpL_GvpF PF06386.6 CDI87733.1 - 0.13 11.8 7.1 0.14 11.7 4.9 1.1 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF SeqA PF03925.8 CDI87733.1 - 0.14 11.8 8.8 0.16 11.6 6.1 1.1 1 0 0 1 1 1 0 SeqA protein AUX_IAA PF02309.11 CDI87733.1 - 0.14 11.9 8.7 0.15 11.8 6.0 1.1 1 0 0 1 1 1 0 AUX/IAA family Ebola_NP PF05505.7 CDI87733.1 - 0.14 10.2 9.4 0.15 10.1 6.5 1.0 1 0 0 1 1 1 0 Ebola nucleoprotein PAT1 PF09770.4 CDI87733.1 - 0.14 10.3 26.6 0.15 10.2 18.4 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Cnd1_N PF12922.2 CDI87733.1 - 0.14 11.7 8.1 0.19 11.3 5.6 1.3 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1, N-term AAA_11 PF13086.1 CDI87733.1 - 0.15 11.6 10.1 0.17 11.4 7.0 1.1 1 0 0 1 1 1 0 AAA domain RNA_pol_Rpb1_5 PF04998.12 CDI87733.1 - 0.15 11.2 6.0 0.18 11.0 4.1 1.0 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 Folate_carrier PF01770.13 CDI87733.1 - 0.16 10.4 6.3 0.16 10.4 4.3 1.0 1 0 0 1 1 1 0 Reduced folate carrier RAB3GAP2_N PF14655.1 CDI87733.1 - 0.16 10.9 9.7 0.21 10.5 6.7 1.2 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus DUF4011 PF13195.1 CDI87733.1 - 0.16 11.9 5.3 0.19 11.7 3.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4011) Band_3_cyto PF07565.8 CDI87733.1 - 0.19 11.1 10.4 0.22 10.9 7.2 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Caudo_TAP PF02413.12 CDI87733.1 - 0.2 11.8 12.0 0.26 11.4 8.3 1.3 1 0 0 1 1 1 0 Caudovirales tail fibre assembly protein Macoilin PF09726.4 CDI87733.1 - 0.26 9.5 10.6 0.3 9.3 7.3 1.0 1 0 0 1 1 1 0 Transmembrane protein DUF3801 PF12687.2 CDI87733.1 - 0.27 10.7 12.8 0.42 10.1 8.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3801) RED_N PF07808.8 CDI87733.1 - 0.28 10.3 12.0 0.32 10.1 8.3 1.2 1 0 0 1 1 1 0 RED-like protein N-terminal region CDK5_activator PF03261.10 CDI87733.1 - 0.28 10.4 10.1 0.29 10.4 7.0 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein DUF913 PF06025.7 CDI87733.1 - 0.29 9.8 10.5 0.32 9.6 7.3 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Neur_chan_memb PF02932.11 CDI87733.1 - 0.33 10.7 6.7 0.37 10.6 4.6 1.0 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Activator_LAG-3 PF11498.3 CDI87733.1 - 0.35 9.5 31.7 0.37 9.4 22.0 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 EIIBC-GUT_N PF03612.9 CDI87733.1 - 0.4 10.2 8.5 0.49 9.9 5.9 1.3 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Paramyxo_C PF01692.13 CDI87733.1 - 0.42 10.2 15.6 0.49 9.9 10.8 1.1 1 0 0 1 1 1 0 Paramyxovirus non-structural protein c Dynamin_N PF00350.18 CDI87733.1 - 0.45 10.3 6.5 0.52 10.1 4.5 1.2 1 0 0 1 1 1 0 Dynamin family OATP PF03137.15 CDI87733.1 - 0.52 8.3 6.5 0.55 8.2 4.5 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family TFIIA PF03153.8 CDI87733.1 - 0.53 10.1 20.6 0.58 10.0 14.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SprA-related PF12118.3 CDI87733.1 - 0.57 9.4 28.6 0.7 9.1 19.8 1.1 1 0 0 1 1 1 0 SprA-related family Lin-8 PF03353.10 CDI87733.1 - 0.65 9.2 14.7 0.72 9.0 10.2 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Nucleoside_tran PF01733.13 CDI87733.1 - 0.7 8.9 3.6 0.77 8.8 2.5 1.1 1 0 0 1 1 1 0 Nucleoside transporter DUF1207 PF06727.6 CDI87733.1 - 0.79 8.4 6.5 0.93 8.2 4.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1207) RR_TM4-6 PF06459.7 CDI87733.1 - 0.8 9.5 13.8 0.87 9.4 9.6 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 LIM_bind PF01803.11 CDI87733.1 - 0.81 8.7 14.1 1 8.3 9.8 1.2 1 0 0 1 1 1 0 LIM-domain binding protein Peptidase_S64 PF08192.6 CDI87733.1 - 0.86 7.8 11.6 0.96 7.6 8.0 1.0 1 0 0 1 1 1 0 Peptidase family S64 Hid1 PF12722.2 CDI87733.1 - 0.92 7.1 14.0 0.99 6.9 9.7 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Het-C PF07217.6 CDI87733.1 - 0.96 7.5 8.7 1 7.4 6.0 1.0 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C Sox_N PF12444.3 CDI87733.1 - 1.1 10.4 11.8 1.5 9.9 8.2 1.2 1 0 0 1 1 1 0 Sox developmental protein N terminal FAM60A PF15396.1 CDI87733.1 - 1.1 8.9 10.6 1.3 8.6 7.4 1.1 1 0 0 1 1 1 0 Protein Family FAM60A DUF3373 PF11853.3 CDI87733.1 - 1.2 7.6 9.1 1.3 7.4 6.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) Ant_C PF05586.6 CDI87733.1 - 1.2 9.6 4.6 1.8 9.0 3.2 1.5 1 1 0 1 1 1 0 Anthrax receptor C-terminus region Ndc1_Nup PF09531.5 CDI87733.1 - 1.4 7.2 9.8 1.5 7.1 6.8 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup eIF3_subunit PF08597.5 CDI87733.1 - 1.5 8.3 12.5 1.8 8.0 8.7 1.1 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit DUF3464 PF11947.3 CDI87733.1 - 1.5 8.2 9.6 1.8 7.9 6.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) AvrE PF11725.3 CDI87733.1 - 1.5 5.7 16.1 1.7 5.5 11.1 1.0 1 0 0 1 1 1 0 Pathogenicity factor DUF4544 PF15077.1 CDI87733.1 - 1.5 8.2 6.5 1.8 8.0 4.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4544) FAM176 PF14851.1 CDI87733.1 - 1.6 8.4 7.5 0.89 9.2 4.0 1.4 1 1 1 2 2 2 0 FAM176 family DUF1675 PF07897.6 CDI87733.1 - 1.7 8.4 12.1 1.9 8.2 8.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) BORG_CEP PF14957.1 CDI87733.1 - 1.8 9.4 11.8 2.3 9.1 8.2 1.1 1 0 0 1 1 1 0 Cdc42 effector DDHD PF02862.12 CDI87733.1 - 1.9 8.2 14.9 2.3 7.9 10.3 1.1 1 0 0 1 1 1 0 DDHD domain DUF4557 PF15101.1 CDI87733.1 - 1.9 8.2 18.3 2.4 7.9 12.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) Glycophorin_A PF01102.13 CDI87733.1 - 1.9 8.2 10.9 2.5 7.8 7.6 1.2 1 0 0 1 1 1 0 Glycophorin A DUF605 PF04652.11 CDI87733.1 - 1.9 7.7 19.9 2.2 7.6 13.8 1.1 1 0 0 1 1 1 0 Vta1 like DUF4407 PF14362.1 CDI87733.1 - 2 7.2 11.2 2.2 7.1 7.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Dicty_REP PF05086.7 CDI87733.1 - 2.2 5.9 15.7 2.4 5.7 10.9 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF1764 PF08576.5 CDI87733.1 - 2.2 9.1 10.8 3.1 8.6 7.5 1.3 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) GRA6 PF05084.8 CDI87733.1 - 2.4 7.6 8.0 2.9 7.3 5.5 1.1 1 0 0 1 1 1 0 Granule antigen protein (GRA6) DUF4400 PF14348.1 CDI87733.1 - 2.5 7.4 5.2 3 7.1 3.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4400) Apt1 PF10351.4 CDI87733.1 - 2.5 6.8 14.1 2.8 6.6 9.8 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain CPSF100_C PF13299.1 CDI87733.1 - 2.5 8.2 11.3 3.1 7.9 7.8 1.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal LMBR1 PF04791.11 CDI87733.1 - 3.1 6.2 5.6 3.4 6.1 3.9 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF2477 PF10631.4 CDI87733.1 - 3.1 8.0 8.8 3.9 7.6 6.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2477) Serinc PF03348.10 CDI87733.1 - 3.2 6.3 11.3 3.7 6.1 7.8 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) FliP PF00813.15 CDI87733.1 - 3.5 7.3 6.8 4.2 7.0 4.7 1.2 1 0 0 1 1 1 0 FliP family Zip PF02535.17 CDI87733.1 - 3.6 6.4 5.7 4.3 6.2 3.9 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter Bul1_N PF04425.7 CDI87733.1 - 4.5 5.7 13.9 5.2 5.5 9.6 1.0 1 0 0 1 1 1 0 Bul1 N terminus AAA_23 PF13476.1 CDI87733.1 - 4.7 7.4 12.1 5.3 7.3 8.4 1.1 1 0 0 1 1 1 0 AAA domain PIH1 PF08190.7 CDI87733.1 - 4.9 6.5 17.8 5.6 6.3 12.3 1.1 1 0 0 1 1 1 0 pre-RNA processing PIH1/Nop17 Rtf2 PF04641.7 CDI87733.1 - 5.4 6.1 12.8 6.5 5.8 8.9 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger Glyco_transf_15 PF01793.11 CDI87733.1 - 5.5 5.8 10.0 6.3 5.6 6.9 1.1 1 0 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase DUF3533 PF12051.3 CDI87733.1 - 5.8 5.5 12.2 6.4 5.4 8.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3533) MDFI PF15316.1 CDI87733.1 - 6.6 6.6 9.2 8.1 6.4 6.4 1.1 1 0 0 1 1 1 0 MyoD family inhibitor DUF106 PF01956.11 CDI87733.1 - 6.6 6.2 13.0 8.3 5.9 9.0 1.2 1 0 0 1 1 1 0 Integral membrane protein DUF106 DivIC PF04977.10 CDI87733.1 - 6.6 6.2 15.2 10 5.6 10.5 1.3 1 0 0 1 1 1 0 Septum formation initiator Senescence_reg PF04520.8 CDI87733.1 - 7 7.1 9.9 8.7 6.8 6.9 1.1 1 0 0 1 1 1 0 Senescence regulator BaxI_1 PF12811.2 CDI87733.1 - 7.1 5.7 7.3 8.2 5.4 5.1 1.2 1 0 0 1 1 1 0 Bax inhibitor 1 like DUF2203 PF09969.4 CDI87733.1 - 7.1 6.8 8.3 9.4 6.4 5.8 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) Shisa PF13908.1 CDI87733.1 - 7.2 6.7 15.0 9 6.4 10.4 1.2 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator DHHW PF14286.1 CDI87733.1 - 7.3 5.7 12.3 8.5 5.5 8.6 1.1 1 0 0 1 1 1 0 DHHW protein 7TM_transglut PF14402.1 CDI87733.1 - 7.7 5.3 7.1 10 4.9 4.9 1.1 1 0 0 1 1 1 0 7 transmembrane helices usually fused to an inactive transglutaminase BAF1_ABF1 PF04684.8 CDI87733.1 - 7.9 5.1 23.7 8.9 5.0 16.5 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor SID-1_RNA_chan PF13965.1 CDI87733.1 - 8.3 4.4 8.7 8.9 4.3 6.0 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Baculo_PP31 PF05311.6 CDI87733.1 - 8.7 5.5 13.3 10 5.2 9.2 1.2 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) U1snRNP70_N PF12220.3 CDI87733.1 - 9.5 6.6 16.7 13 6.1 11.4 1.5 1 1 0 1 1 1 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal Cyclin PF08613.6 CDI87736.1 - 3.6e-30 105.3 0.0 6.2e-30 104.5 0.0 1.4 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 CDI87736.1 - 8.9e-12 44.6 0.7 1.4e-11 44.0 0.5 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain ketoacyl-synt PF00109.21 CDI87737.1 - 2e-79 266.6 0.1 9.4e-79 264.4 0.0 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 CDI87737.1 - 1.7e-57 194.0 0.0 4.3e-57 192.6 0.0 1.8 1 0 0 1 1 1 1 KR domain Acyl_transf_1 PF00698.16 CDI87737.1 - 2e-54 185.0 1.3 3.3e-54 184.3 0.9 1.3 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.1 CDI87737.1 - 1.8e-48 165.2 0.9 2.9e-48 164.5 0.6 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase adh_short PF00106.20 CDI87737.1 - 6.3e-48 162.8 0.0 2.4e-47 160.9 0.0 2.1 2 0 0 2 2 2 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 CDI87737.1 - 2.6e-42 143.4 1.0 4.4e-42 142.6 0.2 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.20 CDI87737.1 - 2.1e-12 47.1 0.0 5.1e-12 45.8 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Epimerase PF01370.16 CDI87737.1 - 9.6e-05 21.9 0.0 0.00017 21.0 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Thiolase_N PF00108.18 CDI87737.1 - 0.003 16.6 0.2 0.0081 15.1 0.0 1.7 2 0 0 2 2 2 1 Thiolase, N-terminal domain adh_short_C2 PF13561.1 CDI87737.1 - 0.0032 17.2 0.0 0.0068 16.1 0.0 1.5 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Polysacc_synt_2 PF02719.10 CDI87737.1 - 0.13 11.1 0.0 0.21 10.4 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein DUF1015 PF06245.6 CDI87737.1 - 0.36 9.2 0.0 0.6 8.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1015) TSGP1 PF07771.6 CDI87738.1 - 1.9 8.4 14.4 1.9 8.4 4.0 2.2 2 0 0 2 2 2 0 Tick salivary peptide group 1 FNIP_N PF14636.1 CDI87738.1 - 2.3 8.7 19.1 0.16 12.4 7.3 2.0 2 0 0 2 2 2 0 Folliculin-interacting protein N-terminus CorA PF01544.13 CDI87738.1 - 2.8 6.9 6.9 4.1 6.3 4.8 1.3 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Peptidase_S15 PF02129.13 CDI87738.1 - 4.9 6.4 8.7 5.6 6.2 6.1 1.3 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) GET2 PF08690.5 CDI87738.1 - 5.8 6.0 16.0 7.3 5.7 11.1 1.1 1 0 0 1 1 1 0 GET complex subunit GET2 Dicty_REP PF05086.7 CDI87738.1 - 7.2 4.2 16.9 7.6 4.1 11.7 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein UPF0051 PF01458.12 CDI87739.1 - 1.5e-09 37.6 1.8 8.5e-08 31.9 0.0 3.0 1 1 1 2 2 2 1 Uncharacterized protein family (UPF0051) SKIP_SNW PF02731.10 CDI87739.1 - 0.039 13.3 9.2 0.18 11.2 0.1 2.3 2 0 0 2 2 2 0 SKIP/SNW domain Corona_nucleoca PF00937.13 CDI87739.1 - 0.044 12.7 19.8 0.0091 14.9 5.6 2.2 2 0 0 2 2 2 0 Coronavirus nucleocapsid protein Totivirus_coat PF05518.6 CDI87739.1 - 0.044 11.6 11.2 0.06 11.1 7.8 1.3 1 0 0 1 1 1 0 Totivirus coat protein GRP PF07172.6 CDI87739.1 - 0.066 13.6 1.9 0.24 11.9 0.2 2.5 2 0 0 2 2 2 0 Glycine rich protein family Kin17_mid PF10357.4 CDI87739.1 - 0.18 11.4 12.0 0.21 11.2 0.4 2.5 2 0 0 2 2 2 0 Domain of Kin17 curved DNA-binding protein DUF605 PF04652.11 CDI87739.1 - 0.41 9.9 27.8 0.63 9.3 19.3 1.2 1 0 0 1 1 1 0 Vta1 like Activator_LAG-3 PF11498.3 CDI87739.1 - 0.43 9.2 49.3 0.028 13.1 7.9 2.3 2 0 0 2 2 2 0 Transcriptional activator LAG-3 DUF4175 PF13779.1 CDI87739.1 - 1.3 6.6 34.2 0.19 9.3 13.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4175) CAF-1_p150 PF11600.3 CDI87739.1 - 2.1 7.6 26.1 0.11 11.8 6.8 2.3 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal ASFV_J13L PF05568.6 CDI87739.1 - 5.3 6.5 14.7 11 5.5 10.2 1.6 1 0 0 1 1 1 0 African swine fever virus J13L protein LcrG PF07216.7 CDI87739.1 - 5.4 7.1 15.7 3.7 7.6 1.0 3.4 3 0 0 3 3 3 0 LcrG protein Conotoxin PF02950.12 CDI87739.1 - 6.2 7.6 10.1 1.2 10.0 0.9 3.2 3 0 0 3 3 3 0 Conotoxin Macoilin PF09726.4 CDI87739.1 - 7.1 4.7 21.5 11 4.2 14.9 1.2 1 0 0 1 1 1 0 Transmembrane protein HSP90 PF00183.13 CDI87740.1 - 4.5e-260 863.5 44.7 5.2e-260 863.3 31.0 1.0 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.21 CDI87740.1 - 3.8e-12 45.8 0.0 7.7e-12 44.9 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 CDI87740.1 - 1.7e-10 40.6 0.1 1.7e-10 40.6 0.1 2.5 2 1 0 2 2 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase LOH1CR12 PF10158.4 CDI87740.1 - 0.0039 16.9 1.3 0.0096 15.7 0.2 2.2 2 0 0 2 2 2 1 Tumour suppressor protein CDC45 PF02724.9 CDI87740.1 - 0.22 9.4 15.4 0.36 8.8 10.7 1.2 1 0 0 1 1 1 0 CDC45-like protein RR_TM4-6 PF06459.7 CDI87740.1 - 0.29 10.9 25.1 0.02 14.8 13.5 1.9 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 DUF3499 PF12005.3 CDI87740.1 - 0.34 11.0 2.0 0.94 9.6 1.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3499) Zip PF02535.17 CDI87740.1 - 0.4 9.6 2.3 0.62 9.0 1.6 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter DDHD PF02862.12 CDI87740.1 - 1.1 9.0 16.1 0.12 12.1 7.6 1.9 2 0 0 2 2 2 0 DDHD domain DUF1510 PF07423.6 CDI87740.1 - 1.3 8.3 32.1 0.038 13.3 17.7 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) LMBR1 PF04791.11 CDI87740.1 - 5.4 5.4 4.7 9.2 4.7 3.2 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein Rtf2 PF04641.7 CDI87741.1 - 4.2 6.4 33.4 5 6.2 23.1 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger DUF1510 PF07423.6 CDI87741.1 - 5 6.4 39.0 6.2 6.1 27.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) MitoNEET_N PF10660.4 CDI87742.1 - 0.054 13.3 0.2 0.1 12.4 0.1 1.4 1 0 0 1 1 1 0 Iron-containing outer mitochondrial membrane protein N-terminus DUF202 PF02656.10 CDI87742.1 - 0.069 13.3 1.5 0.11 12.7 1.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF202) Chordopox_A33R PF05966.7 CDI87742.1 - 0.11 11.3 0.0 0.16 10.7 0.0 1.2 1 0 0 1 1 1 0 Chordopoxvirus A33R protein Cnd1 PF12717.2 CDI87743.1 - 5.4e-12 45.9 0.0 1.3e-11 44.6 0.0 1.6 1 0 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1 RAB3GAP2_N PF14655.1 CDI87743.1 - 0.00078 18.5 1.9 0.00078 18.5 1.3 3.1 3 0 0 3 3 3 1 Rab3 GTPase-activating protein regulatory subunit N-terminus DUF2391 PF09622.5 CDI87743.1 - 0.2 10.7 5.1 0.11 11.6 0.3 2.4 2 0 0 2 2 2 0 Putative integral membrane protein (DUF2391) Guanylate_cyc PF00211.15 CDI87745.1 - 3.1e-18 65.7 1.0 4.4e-18 65.3 0.1 1.6 2 0 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain Ion_trans PF00520.26 CDI87745.1 - 1.9e-08 33.8 3.8 1.9e-08 33.8 2.6 2.0 2 0 0 2 2 2 1 Ion transport protein DUF2865 PF11064.3 CDI87747.1 - 0.082 12.7 0.0 0.12 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2865) RabGAP-TBC PF00566.13 CDI87748.1 - 6.5e-41 140.1 6.4 8.7e-41 139.7 4.4 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain PTS_EIIC_2 PF13303.1 CDI87748.1 - 0.022 13.6 10.4 0.036 12.9 7.2 1.2 1 0 0 1 1 1 0 Phosphotransferase system, EIIC IncA PF04156.9 CDI87748.1 - 2.7 7.5 6.3 4.1 6.9 4.4 1.3 1 0 0 1 1 1 0 IncA protein DUF2057 PF09829.4 CDI87748.1 - 3.6 7.1 7.2 6.3 6.4 0.4 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2057) Na_H_Exchanger PF00999.16 CDI87749.1 - 1.5e-08 33.5 9.3 2.1e-08 33.1 6.4 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Med3 PF11593.3 CDI87749.1 - 7.2 5.7 14.7 6.1 5.9 2.2 2.1 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal DUF2052 PF09747.4 CDI87750.1 - 0.012 15.4 14.7 0.2 11.5 1.4 2.2 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) DUF966 PF06136.8 CDI87750.1 - 0.093 12.1 13.6 0.072 12.5 1.5 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF966) PAT1 PF09770.4 CDI87750.1 - 0.88 7.7 57.4 0.19 9.9 18.4 2.0 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 Neur_chan_memb PF02932.11 CDI87750.1 - 1.7 8.4 17.3 21 4.8 12.0 2.1 1 1 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DDHD PF02862.12 CDI87750.1 - 1.9 8.2 11.2 0.74 9.5 1.3 2.1 2 0 0 2 2 2 0 DDHD domain AIF_C PF14721.1 CDI87750.1 - 3 8.0 12.0 0.21 11.8 1.0 2.6 2 1 1 3 3 3 0 Apoptosis-inducing factor, mitochondrion-associated, C-term DUF2076 PF09849.4 CDI87750.1 - 4.5 7.2 37.2 1.1 9.2 11.1 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2076) OATP PF03137.15 CDI87750.1 - 7.6 4.4 8.1 2.7 5.9 1.8 2.2 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family TFIIA PF03153.8 CDI87750.1 - 9.5 6.0 38.8 1.9 8.2 9.2 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Tubulin PF00091.20 CDI87751.1 - 8.6e-71 238.1 0.0 1.3e-70 237.6 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 CDI87751.1 - 2.8e-49 166.3 0.1 4.2e-49 165.7 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 CDI87751.1 - 9.3e-05 22.4 0.0 0.00019 21.4 0.0 1.5 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.1 CDI87751.1 - 0.0062 16.0 0.0 0.012 15.1 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain PHB_acc_N PF07879.6 CDI87751.1 - 0.16 11.7 0.0 0.32 10.7 0.0 1.5 1 0 0 1 1 1 0 PHB/PHA accumulation regulator DNA-binding domain gag-asp_proteas PF13975.1 CDI87752.1 - 0.038 13.8 0.0 0.28 11.0 0.0 2.2 2 1 0 2 2 2 0 gag-polyprotein putative aspartyl protease IF4E PF01652.13 CDI87753.1 - 3.7e-05 23.3 0.0 6.8e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Band_3_cyto PF07565.8 CDI87753.1 - 0.067 12.6 0.4 0.12 11.8 0.3 1.4 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Spt20 PF12090.3 CDI87753.1 - 0.26 10.6 3.1 0.42 9.9 2.2 1.2 1 0 0 1 1 1 0 Spt20 family FimP PF09766.4 CDI87753.1 - 1.1 8.2 8.4 1.8 7.5 5.8 1.2 1 0 0 1 1 1 0 Fms-interacting protein MRP-S25 PF13741.1 CDI87754.1 - 0.3 10.5 19.2 0.32 10.4 13.3 1.0 1 0 0 1 1 1 0 Mitochondrial ribosomal protein S25 Spore_coat_CotO PF14153.1 CDI87754.1 - 0.56 9.6 21.9 0.54 9.6 15.2 1.1 1 0 0 1 1 1 0 Spore coat protein CotO DUF1764 PF08576.5 CDI87754.1 - 0.67 10.7 18.9 0.71 10.6 13.1 1.1 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) DUF702 PF05142.7 CDI87754.1 - 1 9.5 14.0 1.1 9.4 9.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF702) AMP-binding PF00501.23 CDI87754.1 - 1.1 7.6 5.3 1.1 7.5 3.6 1.0 1 0 0 1 1 1 0 AMP-binding enzyme Paf1 PF03985.8 CDI87754.1 - 1.2 7.7 19.8 1.2 7.8 13.7 1.0 1 0 0 1 1 1 0 Paf1 NARP1 PF12569.3 CDI87754.1 - 1.3 7.6 15.8 1.3 7.7 10.9 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 PH_4 PF15404.1 CDI87754.1 - 1.6 8.1 12.8 1.9 8.0 8.9 1.2 1 0 0 1 1 1 0 Pleckstrin homology domain FLO_LFY PF01698.11 CDI87754.1 - 1.8 7.3 14.7 1.7 7.4 10.2 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein Folate_carrier PF01770.13 CDI87754.1 - 1.9 6.8 14.1 2 6.8 9.8 1.0 1 0 0 1 1 1 0 Reduced folate carrier Chitin_bind_3 PF03067.10 CDI87754.1 - 2.3 8.4 19.2 3.1 8.0 13.3 1.2 1 0 0 1 1 1 0 Chitin binding domain FYDLN_acid PF09538.5 CDI87754.1 - 3.6 8.2 9.0 3.9 8.0 6.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) AAA_23 PF13476.1 CDI87754.1 - 4.4 7.5 20.7 4.6 7.5 14.4 1.1 1 0 0 1 1 1 0 AAA domain FAM60A PF15396.1 CDI87754.1 - 4.5 6.9 12.1 4.4 6.9 8.4 1.1 1 0 0 1 1 1 0 Protein Family FAM60A AIF_C PF14721.1 CDI87754.1 - 4.8 7.4 15.8 5.3 7.2 11.0 1.1 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Pal1 PF08316.6 CDI87754.1 - 4.9 7.6 10.7 5.1 7.5 7.4 1.1 1 0 0 1 1 1 0 Pal1 cell morphology protein SprA-related PF12118.3 CDI87754.1 - 5.1 6.3 42.9 4.9 6.3 29.7 1.0 1 0 0 1 1 1 0 SprA-related family Band_3_cyto PF07565.8 CDI87754.1 - 5.7 6.3 17.4 5.6 6.3 12.1 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain DDHD PF02862.12 CDI87754.1 - 5.7 6.6 16.3 5.3 6.7 11.3 1.1 1 0 0 1 1 1 0 DDHD domain DUF3381 PF11861.3 CDI87754.1 - 6.4 6.2 16.6 7.1 6.1 11.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) Tim54 PF11711.3 CDI87754.1 - 6.7 5.1 13.1 6.7 5.1 9.1 1.0 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Peptidase_S49_N PF08496.5 CDI87754.1 - 6.8 6.4 15.6 7.2 6.3 10.8 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal AUX_IAA PF02309.11 CDI87754.1 - 7.2 6.2 16.2 7 6.3 11.2 1.1 1 0 0 1 1 1 0 AUX/IAA family eIF-3_zeta PF05091.7 CDI87754.1 - 9.1 4.7 26.2 8.6 4.8 18.1 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) RR_TM4-6 PF06459.7 CDI87754.1 - 9.4 6.0 18.4 9.1 6.0 12.8 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SOBP PF15279.1 CDI87755.1 - 0.01 16.2 10.2 0.014 15.8 7.0 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein TraG-D_C PF12696.2 CDI87755.1 - 0.34 10.7 3.4 0.64 9.8 2.4 1.4 1 0 0 1 1 1 0 TraM recognition site of TraD and TraG CAF-1_p150 PF11600.3 CDI87755.1 - 0.44 9.8 15.1 0.79 9.0 10.5 1.4 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal SOG2 PF10428.4 CDI87755.1 - 1.1 7.7 15.8 1.5 7.3 11.0 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Patatin PF01734.17 CDI87755.1 - 1.4 8.7 8.1 2.2 8.1 5.6 1.5 1 1 0 1 1 1 0 Patatin-like phospholipase PAT1 PF09770.4 CDI87755.1 - 3.2 5.8 10.0 4 5.5 6.9 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Apt1 PF10351.4 CDI87755.1 - 3.9 6.2 8.2 5.1 5.8 5.7 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain RVT_1 PF00078.22 CDI87756.1 - 0.0002 20.7 0.0 0.00041 19.7 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) STOP PF05217.7 CDI87758.1 - 1.2e-48 165.6 8.6 6.9e-26 91.3 1.1 2.1 1 1 1 2 2 2 2 STOP protein SR-25 PF10500.4 CDI87759.1 - 0.0014 18.1 31.8 0.0023 17.4 22.1 1.4 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Spore_coat_CotO PF14153.1 CDI87759.1 - 0.042 13.2 10.2 0.055 12.9 7.1 1.4 1 0 0 1 1 1 0 Spore coat protein CotO DUF1510 PF07423.6 CDI87759.1 - 0.32 10.3 18.3 0.46 9.8 12.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Plexin_cytopl PF08337.7 CDI87759.1 - 0.39 8.9 0.0 0.39 8.9 0.0 2.1 2 0 0 2 2 2 0 Plexin cytoplasmic RasGAP domain Peptidase_S49_N PF08496.5 CDI87759.1 - 1.1 9.0 7.1 1.8 8.3 4.9 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Serinc PF03348.10 CDI87759.1 - 2.1 6.9 10.2 2.6 6.6 7.1 1.3 1 0 0 1 1 1 0 Serine incorporator (Serinc) Bac_GDH PF05088.7 CDI87759.1 - 2.2 5.5 17.9 2.7 5.2 12.4 1.0 1 0 0 1 1 1 0 Bacterial NAD-glutamate dehydrogenase Utp14 PF04615.8 CDI87759.1 - 7.3 4.6 23.7 8.2 4.4 16.4 1.1 1 0 0 1 1 1 0 Utp14 protein Aldo_ket_red PF00248.16 CDI87761.1 - 4.7e-10 38.7 0.0 2.2e-05 23.4 0.0 2.2 2 0 0 2 2 2 2 Aldo/keto reductase family SAPS PF04499.10 CDI87762.1 - 0.00053 18.7 14.4 0.00059 18.5 10.0 1.0 1 0 0 1 1 1 1 SIT4 phosphatase-associated protein Plasmodium_Vir PF05795.6 CDI87762.1 - 0.00068 18.9 5.3 0.0011 18.2 3.7 1.3 1 1 0 1 1 1 1 Plasmodium vivax Vir protein CDC45 PF02724.9 CDI87762.1 - 0.00076 17.6 14.6 0.00087 17.4 10.1 1.0 1 0 0 1 1 1 1 CDC45-like protein DUF2077 PF09850.4 CDI87762.1 - 0.0023 17.3 3.1 0.0023 17.3 2.2 2.0 1 1 1 2 2 1 1 Uncharacterized protein conserved in bacteria (DUF2077) Tim54 PF11711.3 CDI87762.1 - 0.003 16.2 10.8 0.0035 16.0 7.5 1.0 1 0 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 VIT1 PF01988.14 CDI87762.1 - 0.0058 16.1 3.8 0.0073 15.8 2.6 1.1 1 0 0 1 1 1 1 VIT family Ycf1 PF05758.7 CDI87762.1 - 0.0084 13.8 19.7 0.009 13.7 13.7 1.0 1 0 0 1 1 1 1 Ycf1 DHHW PF14286.1 CDI87762.1 - 0.014 14.7 13.6 0.016 14.5 9.4 1.1 1 0 0 1 1 1 0 DHHW protein DUF912 PF06024.7 CDI87762.1 - 0.015 15.3 26.9 82 3.3 18.7 2.4 1 1 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) RR_TM4-6 PF06459.7 CDI87762.1 - 0.017 15.0 17.5 0.023 14.6 12.1 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 HCO3_cotransp PF00955.16 CDI87762.1 - 0.017 13.8 6.8 0.021 13.5 4.7 1.1 1 0 0 1 1 1 0 HCO3- transporter family DUF913 PF06025.7 CDI87762.1 - 0.018 13.8 9.5 0.022 13.4 6.6 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Raftlin PF15250.1 CDI87762.1 - 0.02 13.4 18.7 0.024 13.1 13.0 1.0 1 0 0 1 1 1 0 Raftlin LMBR1 PF04791.11 CDI87762.1 - 0.027 13.0 7.9 0.031 12.8 5.4 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Zip PF02535.17 CDI87762.1 - 0.032 13.2 24.2 0.069 12.1 16.8 1.6 1 1 0 1 1 1 0 ZIP Zinc transporter DUF1510 PF07423.6 CDI87762.1 - 0.038 13.3 24.0 0.049 13.0 16.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Otopetrin PF03189.8 CDI87762.1 - 0.043 12.8 10.7 0.054 12.4 7.4 1.1 1 0 0 1 1 1 0 Otopetrin NPR3 PF03666.8 CDI87762.1 - 0.047 12.2 20.6 0.056 11.9 14.3 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Suf PF05843.9 CDI87762.1 - 0.049 13.3 29.4 0.08 12.6 20.4 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Ndc1_Nup PF09531.5 CDI87762.1 - 0.05 12.0 15.7 0.062 11.7 10.9 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup MDFI PF15316.1 CDI87762.1 - 0.052 13.5 12.2 0.065 13.2 8.5 1.1 1 0 0 1 1 1 0 MyoD family inhibitor DUF2146 PF10220.4 CDI87762.1 - 0.071 11.0 17.2 0.082 10.8 11.9 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2146) ISK_Channel PF02060.10 CDI87762.1 - 0.1 12.1 0.5 0.17 11.4 0.1 1.7 1 1 1 2 2 2 0 Slow voltage-gated potassium channel FUSC PF04632.7 CDI87762.1 - 0.12 10.7 5.7 0.15 10.4 4.0 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family Patched PF02460.13 CDI87762.1 - 0.15 9.9 9.8 0.25 9.1 6.8 1.4 1 1 0 1 1 1 0 Patched family BTV_NS2 PF04514.7 CDI87762.1 - 0.18 10.6 20.1 0.21 10.4 13.9 1.0 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 SID-1_RNA_chan PF13965.1 CDI87762.1 - 0.18 9.9 15.7 0.21 9.7 10.9 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Sec62 PF03839.11 CDI87762.1 - 0.18 11.1 15.8 0.25 10.7 10.9 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 SET PF00856.23 CDI87762.1 - 0.3 11.3 2.8 0.36 11.1 2.0 1.1 1 0 0 1 1 1 0 SET domain Dsh_C PF12316.3 CDI87762.1 - 0.3 11.1 12.2 0.34 10.9 8.5 1.1 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal FAM60A PF15396.1 CDI87762.1 - 0.32 10.6 19.6 0.4 10.3 13.6 1.1 1 0 0 1 1 1 0 Protein Family FAM60A DDRGK PF09756.4 CDI87762.1 - 0.36 10.1 31.4 0.52 9.6 21.8 1.2 1 0 0 1 1 1 0 DDRGK domain FliP PF00813.15 CDI87762.1 - 0.47 10.1 8.4 0.71 9.5 5.8 1.4 1 0 0 1 1 1 0 FliP family DUF4448 PF14610.1 CDI87762.1 - 0.86 9.0 11.3 3 7.2 7.9 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF4448) Mem_trans PF03547.13 CDI87762.1 - 1.1 7.4 11.0 1.4 7.1 7.7 1.2 1 0 0 1 1 1 0 Membrane transport protein OPT PF03169.10 CDI87762.1 - 1.2 7.4 4.3 3.4 5.9 3.0 1.7 1 1 0 1 1 1 0 OPT oligopeptide transporter protein RNA_pol_Rpb1_5 PF04998.12 CDI87762.1 - 1.6 7.9 12.7 2.1 7.5 8.8 1.2 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 GET2 PF08690.5 CDI87762.1 - 1.8 7.7 18.4 2.2 7.4 12.8 1.1 1 0 0 1 1 1 0 GET complex subunit GET2 Pex16 PF08610.5 CDI87762.1 - 2.5 7.0 21.7 4.1 6.3 15.0 1.3 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) MRP-S26 PF14943.1 CDI87762.1 - 2.9 7.4 28.0 4.9 6.6 19.4 1.3 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 DUF3492 PF11997.3 CDI87762.1 - 3.1 7.2 15.0 3.9 6.9 10.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3492) Herpes_UL87 PF03043.9 CDI87762.1 - 3.6 5.8 16.3 4.2 5.6 11.3 1.0 1 0 0 1 1 1 0 Herpesvirus UL87 family Vma12 PF11712.3 CDI87762.1 - 3.9 7.1 18.1 25 4.5 12.5 1.9 1 1 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase YscJ_FliF_C PF08345.6 CDI87762.1 - 3.9 7.4 24.7 5.3 6.9 17.1 1.1 1 0 0 1 1 1 0 Flagellar M-ring protein C-terminal Kei1 PF08552.6 CDI87762.1 - 5.3 6.6 22.2 80 2.8 15.4 2.0 1 1 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 Herpes_PAP PF03325.8 CDI87762.1 - 5.4 6.4 15.8 6.7 6.1 10.9 1.1 1 0 0 1 1 1 0 Herpesvirus polymerase accessory protein vMSA PF00695.14 CDI87762.1 - 6.3 5.8 14.3 7.8 5.5 9.9 1.2 1 0 0 1 1 1 0 Major surface antigen from hepadnavirus DUF1800 PF08811.6 CDI87762.1 - 6.4 5.5 26.4 7.6 5.3 18.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1800) DUF4045 PF13254.1 CDI87762.1 - 6.5 5.9 24.7 7.7 5.6 17.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) DUF2956 PF11169.3 CDI87762.1 - 7.3 6.6 35.5 0.041 13.8 7.5 2.1 1 1 1 2 2 1 0 Protein of unknown function (DUF2956) WTX PF09422.5 CDI87762.1 - 7.6 5.3 18.0 8.5 5.2 12.4 1.0 1 0 0 1 1 1 0 WTX protein ALMT PF11744.3 CDI87762.1 - 7.7 5.0 10.0 8.2 4.9 6.9 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter Pox_Ag35 PF03286.9 CDI87762.1 - 7.7 5.9 17.4 10 5.5 12.0 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Hid1 PF12722.2 CDI87762.1 - 7.8 4.0 30.9 9.2 3.7 21.4 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein eIF-3_zeta PF05091.7 CDI87762.1 - 8.4 4.8 30.8 11 4.5 21.3 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) SPX PF03105.14 CDI87762.1 - 8.5 6.0 26.7 11 5.6 18.5 1.1 1 0 0 1 1 1 0 SPX domain GAGA_bind PF06217.7 CDI87762.1 - 8.8 6.1 28.4 9.8 6.0 19.7 1.0 1 0 0 1 1 1 0 GAGA binding protein-like family KR PF08659.5 CDI87764.1 - 4.7e-52 176.2 0.0 2.6e-51 173.8 0.0 2.3 1 1 0 1 1 1 1 KR domain Acyl_transf_1 PF00698.16 CDI87764.1 - 5.7e-47 160.5 4.3 3.9e-43 147.9 1.3 2.3 1 1 1 2 2 2 2 Acyl transferase domain adh_short PF00106.20 CDI87764.1 - 4.4e-43 147.0 0.1 9e-42 142.8 0.1 3.2 2 1 0 2 2 2 1 short chain dehydrogenase PS-DH PF14765.1 CDI87764.1 - 5.3e-33 114.4 0.1 1.6e-32 112.8 0.0 1.8 1 1 0 1 1 1 1 Polyketide synthase dehydratase PP-binding PF00550.20 CDI87764.1 - 9.8e-07 28.9 0.1 2e-06 27.9 0.1 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site Ketoacyl-synt_C PF02801.17 CDI87764.1 - 2e-06 27.6 0.6 7.1e-06 25.8 0.4 2.1 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Abhydrolase_5 PF12695.2 CDI87764.1 - 0.049 13.3 0.4 0.16 11.7 0.1 2.0 2 0 0 2 2 2 0 Alpha/beta hydrolase family Corona_nucleoca PF00937.13 CDI87765.1 - 0.0028 16.6 14.3 0.003 16.5 9.9 1.0 1 0 0 1 1 1 1 Coronavirus nucleocapsid protein TMEM154 PF15102.1 CDI87765.1 - 0.003 17.2 0.8 0.0035 17.0 0.5 1.1 1 0 0 1 1 1 1 TMEM154 protein family OPT PF03169.10 CDI87765.1 - 0.04 12.3 0.4 0.043 12.2 0.3 1.0 1 0 0 1 1 1 0 OPT oligopeptide transporter protein Med3 PF11593.3 CDI87765.1 - 0.055 12.7 19.5 0.058 12.6 13.5 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Zip PF02535.17 CDI87765.1 - 0.34 9.8 11.8 0.39 9.6 8.2 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter EspB PF05802.6 CDI87765.1 - 0.68 8.8 7.8 0.77 8.6 5.4 1.0 1 0 0 1 1 1 0 Enterobacterial EspB protein RAP1 PF07218.6 CDI87765.1 - 0.68 7.9 8.8 0.62 8.0 6.1 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) TAS2R PF05296.8 CDI87765.1 - 0.7 8.7 6.3 0.81 8.5 4.4 1.0 1 0 0 1 1 1 0 Mammalian taste receptor protein (TAS2R) Presenilin PF01080.12 CDI87765.1 - 1.3 7.7 10.2 1.4 7.6 7.1 1.1 1 0 0 1 1 1 0 Presenilin SSP160 PF06933.6 CDI87765.1 - 2.4 6.0 14.9 2.7 5.8 10.3 1.0 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DivIC PF04977.10 CDI87765.1 - 3 7.3 7.2 4.7 6.7 5.0 1.3 1 0 0 1 1 1 0 Septum formation initiator Neur_chan_memb PF02932.11 CDI87765.1 - 5.4 6.8 9.5 6.4 6.5 6.6 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region RseC_MucC PF04246.7 CDI87767.1 - 0.062 12.8 0.3 4.6 6.8 0.0 2.6 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC Caldesmon PF02029.10 CDI87767.1 - 3 6.1 5.8 6.2 5.1 1.7 2.0 2 0 0 2 2 2 0 Caldesmon ERG4_ERG24 PF01222.12 CDI87769.1 - 0.2 10.1 0.9 0.24 9.8 0.6 1.0 1 0 0 1 1 1 0 Ergosterol biosynthesis ERG4/ERG24 family Ribosomal_60s PF00428.14 CDI87769.1 - 0.51 10.7 5.7 0.87 10.0 3.9 1.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein DUF4366 PF14283.1 CDI87769.1 - 0.7 9.2 8.9 0.91 8.9 6.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) DUF3357 PF11837.3 CDI87769.1 - 0.72 9.7 5.3 0.24 11.2 1.7 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3357) Trp_oprn_chp PF09534.5 CDI87769.1 - 0.81 9.2 7.5 1.1 8.7 5.2 1.3 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Presenilin PF01080.12 CDI87769.1 - 0.88 8.3 8.1 1 8.0 5.6 1.2 1 0 0 1 1 1 0 Presenilin RNase_H2-Ydr279 PF09468.5 CDI87769.1 - 1.3 8.1 17.7 1.5 7.9 12.3 1.0 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) DUF4184 PF13803.1 CDI87769.1 - 5.7 6.1 11.9 5.6 6.1 7.7 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4184) Senescence_reg PF04520.8 CDI87769.1 - 7.1 7.1 11.6 8.5 6.8 8.0 1.3 1 0 0 1 1 1 0 Senescence regulator Herpes_UL87 PF03043.9 CDI87769.1 - 9.8 4.4 19.9 11 4.2 13.8 1.0 1 0 0 1 1 1 0 Herpesvirus UL87 family Pex14_N PF04695.8 CDI87771.1 - 0.003 17.6 10.2 0.003 17.6 7.1 5.2 3 2 1 4 4 4 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Nitroreductase PF00881.19 CDI87772.1 - 0.053 13.3 1.7 0.066 13.0 1.2 1.2 1 0 0 1 1 1 0 Nitroreductase family SprA-related PF12118.3 CDI87772.1 - 0.091 12.0 21.6 0.12 11.6 14.9 1.2 1 0 0 1 1 1 0 SprA-related family DDHD PF02862.12 CDI87772.1 - 0.1 12.4 6.6 0.11 12.3 4.6 1.1 1 0 0 1 1 1 0 DDHD domain Band_3_cyto PF07565.8 CDI87772.1 - 0.15 11.5 11.3 0.2 11.1 7.8 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Gti1_Pac2 PF09729.4 CDI87772.1 - 0.44 10.3 9.6 0.8 9.5 6.6 1.4 1 1 0 1 1 1 0 Gti1/Pac2 family DUF4175 PF13779.1 CDI87772.1 - 0.84 7.2 26.8 0.87 7.2 18.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) DUF4045 PF13254.1 CDI87772.1 - 1.9 7.6 8.4 2.2 7.4 5.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) DUF3464 PF11947.3 CDI87772.1 - 2.2 7.7 5.6 3 7.2 3.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) PAT1 PF09770.4 CDI87772.1 - 3 5.9 27.6 3.4 5.7 19.1 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Neur_chan_memb PF02932.11 CDI87772.1 - 3.5 7.4 7.8 4.2 7.1 5.4 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF4407 PF14362.1 CDI87772.1 - 7.7 5.3 11.2 9.7 5.0 7.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Caudo_TAP PF02413.12 CDI87772.1 - 8.2 6.6 13.9 3.2 7.9 0.6 2.1 2 0 0 2 2 2 0 Caudovirales tail fibre assembly protein Med15 PF09606.5 CDI87772.1 - 8.9 4.3 34.7 11 4.0 24.1 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal AAA_23 PF13476.1 CDI87772.1 - 9.2 6.5 9.8 11 6.2 6.8 1.1 1 0 0 1 1 1 0 AAA domain CAF-1_p150 PF11600.3 CDI87773.1 - 0.00028 20.3 26.4 0.00028 20.3 18.3 3.3 3 0 0 3 3 3 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal LMBR1 PF04791.11 CDI87773.1 - 0.0015 17.2 0.7 0.0015 17.2 0.5 1.6 2 0 0 2 2 2 1 LMBR1-like membrane protein Dynamin_N PF00350.18 CDI87773.1 - 0.003 17.4 4.8 0.011 15.6 0.9 2.3 2 0 0 2 2 2 1 Dynamin family Tim54 PF11711.3 CDI87773.1 - 0.67 8.4 20.7 0.32 9.5 8.8 2.4 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 FLO_LFY PF01698.11 CDI87773.1 - 1.3 7.8 23.6 0.63 8.8 11.7 2.2 2 0 0 2 2 2 0 Floricaula / Leafy protein GAGA_bind PF06217.7 CDI87773.1 - 1.4 8.7 27.4 0.21 11.4 11.8 2.5 2 0 0 2 2 2 0 GAGA binding protein-like family Spore_coat_CotO PF14153.1 CDI87773.1 - 1.7 8.0 47.5 1.9 7.9 3.5 2.4 2 0 0 2 2 2 0 Spore coat protein CotO Exonuc_VII_L PF02601.10 CDI87773.1 - 2.2 7.4 23.1 0.94 8.6 0.9 2.2 2 0 0 2 2 2 0 Exonuclease VII, large subunit Asp-B-Hydro_N PF05279.6 CDI87773.1 - 6.4 6.5 32.3 14 5.4 0.4 2.2 2 0 0 2 2 2 0 Aspartyl beta-hydroxylase N-terminal region GAF PF01590.21 CDI87774.1 - 4.6e-14 52.8 0.0 1.3e-13 51.3 0.0 1.8 2 0 0 2 2 2 1 GAF domain GAF_3 PF13492.1 CDI87774.1 - 1.2e-12 48.0 0.0 2.3e-12 47.1 0.0 1.5 1 0 0 1 1 1 1 GAF domain GAF_2 PF13185.1 CDI87774.1 - 2.7e-11 44.1 0.0 1.2e-10 42.0 0.0 2.0 2 0 0 2 2 2 1 GAF domain FimP PF09766.4 CDI87774.1 - 0.0026 16.8 5.2 0.0049 16.0 3.6 1.3 1 0 0 1 1 1 1 Fms-interacting protein Suf PF05843.9 CDI87774.1 - 0.12 12.0 7.6 0.012 15.3 2.2 1.6 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) Zip PF02535.17 CDI87774.1 - 1.5 7.7 6.8 0.55 9.1 2.4 2.0 2 0 0 2 2 2 0 ZIP Zinc transporter PAP1 PF08601.5 CDI87774.1 - 1.8 8.1 33.6 0.076 12.6 12.8 2.3 2 0 0 2 2 2 0 Transcription factor PAP1 DUF755 PF05501.6 CDI87774.1 - 4.1 7.4 44.7 2.6 8.1 6.2 3.8 3 0 0 3 3 3 0 Domain of unknown function (DUF755) ATP-synt_J PF04911.7 CDI87774.1 - 5.1 6.6 5.9 2 7.9 0.0 2.9 3 0 0 3 3 3 0 ATP synthase j chain Amino_oxidase PF01593.19 CDI87775.1 - 1.1e-09 37.8 0.0 2.3e-09 36.8 0.0 1.4 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase MutS_IV PF05190.13 CDI87776.1 - 0.075 13.2 0.1 0.14 12.3 0.0 1.4 1 0 0 1 1 1 0 MutS family domain IV Shadoo PF14999.1 CDI87779.1 - 0.028 14.2 0.1 0.028 14.2 0.0 3.9 3 1 1 4 4 4 0 Shadow of prion protein, neuroprotective FimP PF09766.4 CDI87779.1 - 1.1 8.3 34.5 0.12 11.3 13.0 2.2 2 0 0 2 2 2 0 Fms-interacting protein Trp_oprn_chp PF09534.5 CDI87779.1 - 2.6 7.6 37.2 1.7 8.1 9.6 2.4 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) CD20 PF04103.10 CDI87779.1 - 3 7.7 12.6 7.7 6.4 3.3 3.6 2 2 0 2 2 2 0 CD20-like family PH_4 PF15404.1 CDI87779.1 - 4.1 6.8 19.5 6.6 6.2 0.8 2.5 2 0 0 2 2 2 0 Pleckstrin homology domain SUKH-4 PF14435.1 CDI87780.1 - 0.008 15.9 0.2 0.008 15.9 0.1 3.5 5 0 0 5 5 5 1 SUKH-4 immunity protein Pox_RNA_Pol_19 PF05320.7 CDI87782.1 - 0.0023 17.7 3.8 0.0023 17.7 2.6 2.0 2 0 0 2 2 2 1 Poxvirus DNA-directed RNA polymerase 19 kDa subunit Ribosomal_60s PF00428.14 CDI87782.1 - 0.012 15.9 7.9 0.018 15.4 5.5 1.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein Bul1_N PF04425.7 CDI87782.1 - 0.5 8.8 15.0 0.57 8.6 10.4 1.1 1 0 0 1 1 1 0 Bul1 N terminus DUF4448 PF14610.1 CDI87782.1 - 0.8 9.1 6.9 4.4 6.7 0.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF4448) Cwf_Cwc_15 PF04889.7 CDI87782.1 - 0.94 9.1 20.3 1.2 8.8 14.1 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein NDUF_B8 PF05821.6 CDI87782.1 - 3.8 7.1 7.3 20 4.7 2.3 2.1 1 1 1 2 2 2 0 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) Herpes_DNAp_acc PF04929.7 CDI87782.1 - 4.7 6.0 17.8 6.4 5.6 12.4 1.2 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Na_trans_assoc PF06512.8 CDI87782.1 - 5.2 6.9 15.0 6.9 6.5 10.4 1.2 1 0 0 1 1 1 0 Sodium ion transport-associated PAT1 PF09770.4 CDI87782.1 - 9.5 4.3 56.1 11 4.0 38.9 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Spt20 PF12090.3 CDI87783.1 - 0.017 14.4 1.5 0.022 14.0 1.0 1.3 1 0 0 1 1 1 0 Spt20 family Suf PF05843.9 CDI87783.1 - 0.028 14.1 1.1 0.031 13.9 0.8 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) RAB3GAP2_N PF14655.1 CDI87783.1 - 0.071 12.0 3.1 0.1 11.6 2.1 1.3 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus DUF2489 PF10675.4 CDI87783.1 - 0.79 9.3 13.3 3.9 7.1 7.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2489) DUF4175 PF13779.1 CDI87783.1 - 3.2 5.3 15.0 4.7 4.7 10.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Med3 PF11593.3 CDI87783.1 - 3.8 6.6 26.9 4.5 6.4 5.3 2.3 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal Hexokinase_2 PF03727.11 CDI87784.1 - 0.029 13.5 0.4 1.3 8.1 0.0 2.2 2 0 0 2 2 2 0 Hexokinase VBS PF08913.5 CDI87784.1 - 0.057 13.6 0.4 0.23 11.6 0.1 2.2 2 0 0 2 2 2 0 Vinculin Binding Site FliL PF03748.9 CDI87784.1 - 0.26 11.2 1.5 5.8 6.9 0.3 2.5 2 0 0 2 2 2 0 Flagellar basal body-associated protein FliL Activator_LAG-3 PF11498.3 CDI87785.1 - 0.037 12.7 2.1 0.045 12.4 1.5 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Proteasome PF00227.21 CDI87789.1 - 1e-07 31.4 0.1 8e-06 25.2 0.0 2.1 1 1 1 2 2 2 2 Proteasome subunit BPD_transp_2 PF02653.11 CDI87793.1 - 0.0024 16.8 1.3 2.2 7.1 0.0 3.0 3 0 0 3 3 3 2 Branched-chain amino acid transport system / permease component Med15 PF09606.5 CDI87793.1 - 0.44 8.6 93.1 0.42 8.7 32.4 2.6 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal HCO3_cotransp PF00955.16 CDI87793.1 - 4.6 5.7 7.5 2.4 6.7 1.0 2.2 1 1 1 2 2 2 0 HCO3- transporter family Trp_oprn_chp PF09534.5 CDI87794.1 - 3.1 7.3 24.6 0.12 11.9 0.8 2.6 3 0 0 3 3 3 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) SAGA-Tad1 PF12767.2 CDI87795.1 - 0.08 12.5 30.9 1 8.9 18.1 2.2 2 0 0 2 2 2 0 Transcriptional regulator of RNA polII, SAGA, subunit DUF1510 PF07423.6 CDI87795.1 - 0.11 11.8 25.3 0.055 12.8 13.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) Pex16 PF08610.5 CDI87795.1 - 0.56 9.1 26.3 0.58 9.1 14.4 2.1 2 0 0 2 2 2 0 Peroxisomal membrane protein (Pex16) SID-1_RNA_chan PF13965.1 CDI87795.1 - 4.9 5.1 12.6 10 4.1 8.7 1.5 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 RCR PF12273.3 CDI87795.1 - 8.2 6.9 34.1 2.5 8.6 17.1 2.6 2 0 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red XPG_I PF00867.13 CDI87796.1 - 2.3e-25 88.4 0.1 3.4e-25 87.9 0.0 1.3 1 0 0 1 1 1 1 XPG I-region XPG_I_2 PF12813.2 CDI87796.1 - 0.0003 20.3 0.0 0.00037 20.0 0.0 1.3 1 0 0 1 1 1 1 XPG domain containing GIDA PF01134.17 CDI87796.1 - 0.12 11.2 0.0 0.13 11.0 0.0 1.1 1 0 0 1 1 1 0 Glucose inhibited division protein A KAP_NTPase PF07693.9 CDI87797.1 - 0.088 11.7 1.7 0.19 10.6 1.2 1.4 1 0 0 1 1 1 0 KAP family P-loop domain PAT1 PF09770.4 CDI87797.1 - 0.13 10.5 20.4 0.19 9.9 14.1 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Pex16 PF08610.5 CDI87797.1 - 0.13 11.2 4.9 0.22 10.4 3.4 1.3 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) SpoVR PF04293.8 CDI87797.1 - 0.26 9.5 4.8 0.38 9.0 3.3 1.1 1 0 0 1 1 1 0 SpoVR like protein DDRGK PF09756.4 CDI87798.1 - 0.018 14.4 11.3 0.02 14.2 7.9 1.0 1 0 0 1 1 1 0 DDRGK domain DUF1510 PF07423.6 CDI87798.1 - 0.025 13.9 21.2 0.028 13.7 14.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DUF572 PF04502.8 CDI87798.1 - 0.068 12.3 19.2 0.074 12.2 13.3 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF572) Nop25 PF09805.4 CDI87798.1 - 0.082 12.9 15.1 0.097 12.7 10.5 1.0 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) DUF1168 PF06658.7 CDI87798.1 - 0.092 12.2 19.1 0.11 11.9 13.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) Draxin PF15550.1 CDI87798.1 - 0.13 11.8 12.0 0.14 11.8 8.3 1.0 1 0 0 1 1 1 0 Draxin Bud13 PF09736.4 CDI87798.1 - 0.15 12.3 17.2 0.17 12.1 12.0 1.1 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex Apis_Csd PF11671.3 CDI87798.1 - 0.28 10.9 10.6 0.31 10.8 7.4 1.1 1 0 0 1 1 1 0 Complementary sex determiner protein DUF3807 PF12720.2 CDI87798.1 - 0.32 11.1 19.4 0.39 10.8 13.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) Plasmodium_Vir PF05795.6 CDI87798.1 - 0.49 9.5 14.6 0.56 9.3 10.1 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Pox_Ag35 PF03286.9 CDI87798.1 - 0.55 9.7 16.0 0.65 9.4 11.1 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Cwf_Cwc_15 PF04889.7 CDI87798.1 - 0.78 9.3 19.6 0.8 9.3 13.6 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Afi1 PF07792.7 CDI87798.1 - 0.96 9.4 20.5 1.1 9.2 14.2 1.1 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking AMP-binding PF00501.23 CDI87798.1 - 1 7.7 5.3 1.1 7.5 3.7 1.0 1 0 0 1 1 1 0 AMP-binding enzyme NPR3 PF03666.8 CDI87798.1 - 1.1 7.6 22.1 1.3 7.4 15.3 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF2052 PF09747.4 CDI87798.1 - 1.1 9.1 17.5 1.3 8.8 12.1 1.1 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) Red1 PF07964.6 CDI87798.1 - 1.2 7.1 26.6 1.4 6.9 18.4 1.0 1 0 0 1 1 1 0 Rec10 / Red1 FYDLN_acid PF09538.5 CDI87798.1 - 1.3 9.6 5.7 1.6 9.3 4.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) DUF4638 PF15472.1 CDI87798.1 - 1.3 8.5 13.5 1.5 8.3 9.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) Ycf1 PF05758.7 CDI87798.1 - 1.5 6.4 17.2 1.6 6.3 11.9 1.0 1 0 0 1 1 1 0 Ycf1 Med15 PF09606.5 CDI87798.1 - 1.8 6.6 40.5 2 6.4 28.1 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Na_trans_assoc PF06512.8 CDI87798.1 - 1.9 8.4 15.5 2.2 8.1 10.7 1.1 1 0 0 1 1 1 0 Sodium ion transport-associated DUF4045 PF13254.1 CDI87798.1 - 2.3 7.4 22.8 2.5 7.2 15.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) SAPS PF04499.10 CDI87798.1 - 2.4 6.7 20.6 2.7 6.5 14.2 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Utp14 PF04615.8 CDI87798.1 - 2.8 6.0 26.7 3.1 5.8 18.5 1.0 1 0 0 1 1 1 0 Utp14 protein BTV_NS2 PF04514.7 CDI87798.1 - 2.8 6.7 11.9 3 6.6 8.2 1.0 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 DUF2217 PF10265.4 CDI87798.1 - 3 6.5 21.3 3.5 6.2 14.8 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) Asp-B-Hydro_N PF05279.6 CDI87798.1 - 3.1 7.6 10.8 3.5 7.4 7.5 1.0 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Spc7_N PF15402.1 CDI87798.1 - 3.1 5.6 27.2 3.4 5.5 18.9 1.0 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 Dicty_REP PF05086.7 CDI87798.1 - 3.1 5.4 24.3 3.4 5.3 16.9 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Peptidase_S30 PF01577.11 CDI87798.1 - 3.2 7.0 13.1 4 6.7 9.0 1.1 1 0 0 1 1 1 0 Potyvirus P1 protease Tim54 PF11711.3 CDI87798.1 - 3.6 6.0 14.0 3.9 5.9 9.7 1.0 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DUF4175 PF13779.1 CDI87798.1 - 3.7 5.1 34.1 4.2 4.9 23.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Neur_chan_memb PF02932.11 CDI87798.1 - 3.8 7.3 17.7 4.3 7.1 12.3 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF4647 PF15504.1 CDI87798.1 - 4 6.2 22.1 5 5.8 15.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4647) CDC45 PF02724.9 CDI87798.1 - 5 5.0 16.3 5.6 4.8 11.3 1.0 1 0 0 1 1 1 0 CDC45-like protein TFIIA PF03153.8 CDI87798.1 - 5 6.9 31.8 6.1 6.6 22.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit TMEM51 PF15345.1 CDI87798.1 - 6.2 6.4 20.2 7.6 6.1 14.0 1.1 1 0 0 1 1 1 0 Transmembrane protein 51 Pal1 PF08316.6 CDI87798.1 - 6.5 7.2 13.8 9.3 6.6 9.6 1.3 1 0 0 1 1 1 0 Pal1 cell morphology protein FAM60A PF15396.1 CDI87798.1 - 6.6 6.4 20.3 7.9 6.1 14.0 1.2 1 0 0 1 1 1 0 Protein Family FAM60A DUF2981 PF11200.3 CDI87798.1 - 7 5.6 10.1 8.2 5.3 7.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) SelP_N PF04592.9 CDI87798.1 - 7.6 5.8 17.7 9 5.5 12.3 1.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region MMR1 PF08505.5 CDI87798.1 - 7.9 6.4 33.8 9.4 6.1 23.4 1.1 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein Band_3_cyto PF07565.8 CDI87798.1 - 8 5.8 17.8 13 5.2 12.3 1.3 1 0 0 1 1 1 0 Band 3 cytoplasmic domain DUF853 PF05872.7 CDI87798.1 - 8.1 4.6 13.1 9.2 4.4 9.0 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) IncA PF04156.9 CDI87798.1 - 8.9 5.8 20.9 10 5.6 14.5 1.1 1 0 0 1 1 1 0 IncA protein AUX_IAA PF02309.11 CDI87798.1 - 9.2 5.9 20.0 11 5.7 13.8 1.1 1 0 0 1 1 1 0 AUX/IAA family Stn1 PF10451.4 CDI87798.1 - 9.2 5.0 13.2 10 4.8 9.2 1.1 1 0 0 1 1 1 0 Telomere regulation protein Stn1 Miff PF05644.6 CDI87798.1 - 9.9 5.7 18.2 13 5.3 12.6 1.2 1 0 0 1 1 1 0 Mitochondrial and peroxisomal fission factor Mff Activator_LAG-3 PF11498.3 CDI87800.1 - 0.0015 17.3 27.7 0.0015 17.3 19.2 2.3 2 0 0 2 2 2 1 Transcriptional activator LAG-3 IncA PF04156.9 CDI87800.1 - 0.0051 16.4 14.0 0.0051 16.4 9.7 3.1 3 1 0 3 3 3 1 IncA protein Glt_symporter PF03616.9 CDI87800.1 - 3 6.2 6.4 8.2 4.7 4.5 1.7 1 0 0 1 1 1 0 Sodium/glutamate symporter Presenilin PF01080.12 CDI87800.1 - 4.5 5.9 13.6 11 4.7 7.3 2.2 2 0 0 2 2 2 0 Presenilin YbgS PF13985.1 CDI87801.1 - 0.68 9.8 5.9 0.85 9.5 4.1 1.2 1 0 0 1 1 1 0 YbgS-like protein U79_P34 PF03064.11 CDI87801.1 - 1.1 8.7 12.6 1.2 8.5 8.8 1.1 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Daxx PF03344.10 CDI87801.1 - 1.1 7.6 41.8 1.4 7.3 29.0 1.1 1 0 0 1 1 1 0 Daxx Family Nop14 PF04147.7 CDI87801.1 - 1.7 6.4 40.7 2 6.2 28.2 1.1 1 0 0 1 1 1 0 Nop14-like family Cwf_Cwc_15 PF04889.7 CDI87801.1 - 1.8 8.2 25.6 2 8.0 17.8 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein CDC27 PF09507.5 CDI87801.1 - 2 7.5 24.9 2.4 7.2 17.3 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 DUF1510 PF07423.6 CDI87801.1 - 2.2 7.5 33.0 2.6 7.3 22.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) SDA1 PF05285.7 CDI87801.1 - 2.6 7.2 36.0 3 7.0 25.0 1.0 1 0 0 1 1 1 0 SDA1 Zip PF02535.17 CDI87801.1 - 2.6 6.9 8.0 3.2 6.6 5.5 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter DUF913 PF06025.7 CDI87801.1 - 2.6 6.6 5.5 3.3 6.3 3.8 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) MSP1_C PF07462.6 CDI87801.1 - 2.9 6.1 13.3 3.2 6.0 9.2 1.1 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus DUF4045 PF13254.1 CDI87801.1 - 4.3 6.5 10.4 4.9 6.3 7.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) NPR3 PF03666.8 CDI87801.1 - 4.9 5.5 5.8 5.5 5.4 4.0 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Raftlin PF15250.1 CDI87801.1 - 5 5.5 11.8 5.8 5.3 8.2 1.0 1 0 0 1 1 1 0 Raftlin MIP-T3 PF10243.4 CDI87801.1 - 7.8 4.8 29.9 9.3 4.5 20.7 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 CENP-T PF15511.1 CDI87801.1 - 7.8 5.6 26.5 9.4 5.3 18.4 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Spore_coat_CotO PF14153.1 CDI87801.1 - 8.1 5.8 28.6 13 5.2 19.8 1.4 1 0 0 1 1 1 0 Spore coat protein CotO Pilt PF15453.1 CDI87801.1 - 9.3 5.8 19.6 11 5.5 13.6 1.1 1 0 0 1 1 1 0 Protein incorporated later into Tight Junctions PIG-S PF10510.4 CDI87802.1 - 9.1e-08 31.2 2.2 0.019 13.6 1.5 3.4 3 1 0 3 3 3 2 Phosphatidylinositol-glycan biosynthesis class S protein B9-C2 PF07162.6 CDI87803.1 - 0.00022 21.0 0.0 0.00026 20.8 0.0 1.2 1 0 0 1 1 1 1 Ciliary basal body-associated, B9 protein Ribosomal_60s PF00428.14 CDI87804.1 - 0.62 10.5 8.4 0.88 10.0 5.8 1.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein PAT1 PF09770.4 CDI87805.1 - 7.7 4.6 207.2 0.63 8.2 58.7 2.1 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 PmbA_TldD PF01523.11 CDI87806.1 - 0.55 9.4 9.7 0.84 8.8 6.7 1.3 1 1 0 1 1 1 0 Putative modulator of DNA gyrase DEAD PF00270.24 CDI87807.1 - 5.8e-13 48.6 15.9 5.8e-13 48.6 11.0 2.2 2 1 0 2 2 1 1 DEAD/DEAH box helicase FimP PF09766.4 CDI87807.1 - 0.0029 16.7 3.9 0.0029 16.7 2.7 2.2 2 0 0 2 2 2 1 Fms-interacting protein CDC45 PF02724.9 CDI87807.1 - 0.0042 15.1 3.4 0.26 9.2 0.1 2.1 2 0 0 2 2 2 2 CDC45-like protein SR-25 PF10500.4 CDI87807.1 - 0.0054 16.2 6.4 0.0054 16.2 4.4 3.1 2 1 0 2 2 1 1 Nuclear RNA-splicing-associated protein BLVR PF06375.6 CDI87807.1 - 0.0065 16.3 7.9 0.18 11.6 0.5 2.4 3 0 0 3 3 2 2 Bovine leukaemia virus receptor (BLVR) CDK2AP PF09806.4 CDI87807.1 - 0.014 15.6 9.2 0.014 15.6 6.4 2.7 2 1 0 2 2 1 0 Cyclin-dependent kinase 2-associated protein DARPP-32 PF05395.7 CDI87807.1 - 0.021 14.9 2.6 0.021 14.9 1.8 2.2 2 0 0 2 2 2 0 Protein phosphatase inhibitor 1/DARPP-32 Mem_trans PF03547.13 CDI87807.1 - 0.11 10.7 5.1 1.3 7.1 0.3 2.1 2 0 0 2 2 2 0 Membrane transport protein EphA2_TM PF14575.1 CDI87807.1 - 0.17 12.2 0.3 0.17 12.2 0.2 2.7 3 0 0 3 3 2 0 Ephrin type-A receptor 2 transmembrane domain Ribosomal_60s PF00428.14 CDI87807.1 - 0.21 12.0 28.0 0.33 11.3 5.6 2.4 2 0 0 2 2 2 0 60s Acidic ribosomal protein DDHD PF02862.12 CDI87807.1 - 0.33 10.7 11.8 0.3 10.8 0.3 2.2 2 0 0 2 2 2 0 DDHD domain Macoilin PF09726.4 CDI87807.1 - 0.78 7.9 22.0 0.51 8.5 6.9 2.2 2 0 0 2 2 2 0 Transmembrane protein F-protein PF00469.15 CDI87807.1 - 0.87 8.9 7.6 1.8 7.8 0.4 2.3 2 0 0 2 2 2 0 Negative factor, (F-Protein) or Nef YABBY PF04690.8 CDI87807.1 - 1 9.5 13.5 0.21 11.7 0.4 2.3 2 0 0 2 2 2 0 YABBY protein DUF2217 PF10265.4 CDI87807.1 - 1.4 7.6 16.6 1 8.0 4.3 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2217) Neur_chan_memb PF02932.11 CDI87807.1 - 1.5 8.6 14.7 3.4 7.4 0.8 2.1 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Band_3_cyto PF07565.8 CDI87807.1 - 2.2 7.7 14.3 1.6 8.2 2.2 2.2 2 0 0 2 2 2 0 Band 3 cytoplasmic domain Dehydrin PF00257.14 CDI87807.1 - 3.8 7.8 25.4 5.5 7.2 6.8 2.7 2 0 0 2 2 2 0 Dehydrin PAT1 PF09770.4 CDI87807.1 - 5.9 5.0 33.9 0.61 8.2 8.0 2.1 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 TMEM51 PF15345.1 CDI87807.1 - 6.7 6.3 18.3 1.2 8.7 2.0 2.2 2 0 0 2 2 2 0 Transmembrane protein 51 DNA_pol_viral_N PF00242.12 CDI87807.1 - 8.4 5.3 30.4 0.73 8.8 10.2 2.1 2 0 0 2 2 2 0 DNA polymerase (viral) N-terminal domain Miff PF05644.6 CDI87807.1 - 8.4 5.9 15.9 3.3 7.2 1.0 2.1 2 0 0 2 2 2 0 Mitochondrial and peroxisomal fission factor Mff PRP1_N PF06424.7 CDI87808.1 - 0.0025 18.1 8.9 0.0025 18.1 6.1 3.7 3 2 0 3 3 3 1 PRP1 splicing factor, N-terminal NAM-associated PF14303.1 CDI87808.1 - 0.094 13.0 49.0 0.091 13.0 6.6 3.5 3 0 0 3 3 3 0 No apical meristem-associated C-terminal domain Tubulin PF00091.20 CDI87812.1 - 3.4e-40 138.1 0.0 4.9e-40 137.6 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 CDI87812.1 - 5.1e-13 49.1 0.5 4.7e-11 42.8 0.1 2.2 1 1 1 2 2 2 2 Tubulin C-terminal domain OAD_gamma PF04277.8 CDI87813.1 - 0.00067 19.9 0.3 0.00067 19.9 0.2 7.4 5 2 1 6 6 6 1 Oxaloacetate decarboxylase, gamma chain RIC3 PF15361.1 CDI87813.1 - 0.013 15.7 8.8 0.013 15.7 6.1 6.3 3 2 2 6 6 6 0 Resistance to inhibitors of cholinesterase homologue 3 Cytochrom_B_N PF00033.14 CDI87813.1 - 0.59 9.4 4.2 0.66 9.2 0.5 2.6 2 1 1 3 3 3 0 Cytochrome b(N-terminal)/b6/petB Med3 PF11593.3 CDI87816.1 - 0.085 12.0 38.5 0.14 11.3 26.7 1.4 1 1 0 1 1 1 0 Mediator complex subunit 3 fungal Serinc PF03348.10 CDI87816.1 - 0.65 8.6 5.7 0.9 8.1 3.9 1.3 1 0 0 1 1 1 0 Serine incorporator (Serinc) Mitochondr_Som1 PF11093.3 CDI87816.1 - 2.5 7.9 11.5 0.12 12.1 0.4 2.3 2 0 0 2 2 2 0 Mitochondrial export protein Som1 AAA_23 PF13476.1 CDI87816.1 - 2.8 8.2 9.3 3.9 7.7 6.4 1.2 1 0 0 1 1 1 0 AAA domain Serinc PF03348.10 CDI87817.1 - 0.0024 16.6 6.7 0.0024 16.6 4.7 4.0 1 1 2 3 3 3 1 Serine incorporator (Serinc) Herpes_DNAp_acc PF04929.7 CDI87817.1 - 0.0046 15.9 0.6 0.0046 15.9 0.4 2.3 1 1 0 2 2 2 1 Herpes DNA replication accessory factor DUF1183 PF06682.7 CDI87817.1 - 0.0054 16.3 9.1 0.0054 16.3 6.3 2.9 1 1 0 2 2 2 1 Protein of unknown function (DUF1183) DUF912 PF06024.7 CDI87817.1 - 0.0068 16.4 5.6 0.0068 16.4 3.9 4.6 1 1 2 3 3 3 1 Nucleopolyhedrovirus protein of unknown function (DUF912) Conotoxin PF02950.12 CDI87817.1 - 0.013 16.2 1.4 0.013 16.2 0.9 5.0 3 1 0 3 3 3 0 Conotoxin Herpes_gE PF02480.11 CDI87817.1 - 0.026 12.8 0.0 0.026 12.8 0.0 2.3 1 1 0 2 2 2 0 Alphaherpesvirus glycoprotein E DUF3357 PF11837.3 CDI87817.1 - 0.051 13.4 0.1 0.051 13.4 0.1 4.7 1 1 2 3 3 3 0 Domain of unknown function (DUF3357) EphA2_TM PF14575.1 CDI87817.1 - 0.074 13.4 0.5 0.074 13.4 0.4 5.5 2 1 1 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain TAS2R PF05296.8 CDI87817.1 - 8.1 5.2 7.9 3.5 6.4 3.8 1.6 1 1 0 1 1 1 0 Mammalian taste receptor protein (TAS2R) IncA PF04156.9 CDI87818.1 - 0.00044 19.8 22.7 0.00044 19.8 15.7 1.9 1 1 1 2 2 2 1 IncA protein Seryl_tRNA_N PF02403.17 CDI87818.1 - 0.0027 17.7 10.9 0.0027 17.7 7.5 2.9 1 1 2 3 3 3 1 Seryl-tRNA synthetase N-terminal domain NPV_P10 PF05531.7 CDI87818.1 - 0.35 11.1 11.8 1.4 9.2 1.5 3.1 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein V_ATPase_I PF01496.14 CDI87818.1 - 0.4 8.4 17.7 0.65 7.7 12.3 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family RHD PF00554.17 CDI87818.1 - 0.46 10.1 6.2 0.8 9.4 4.0 1.6 1 1 0 1 1 1 0 Rel homology domain (RHD) ATG16 PF08614.6 CDI87818.1 - 0.48 10.2 30.7 0.13 12.1 6.8 2.6 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) AAA_13 PF13166.1 CDI87818.1 - 0.51 8.7 24.9 1 7.7 17.2 1.5 1 1 0 1 1 1 0 AAA domain Reo_sigmaC PF04582.7 CDI87818.1 - 0.59 9.2 4.8 1.2 8.2 1.2 2.1 1 1 1 2 2 2 0 Reovirus sigma C capsid protein Cauli_DNA-bind PF03310.8 CDI87818.1 - 1.2 8.9 8.5 0.29 10.9 1.6 2.4 2 0 0 2 2 2 0 Caulimovirus DNA-binding protein GAS PF13851.1 CDI87818.1 - 1.5 7.9 30.0 4.7 6.3 20.1 2.2 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding TMF_TATA_bd PF12325.3 CDI87818.1 - 2 8.1 27.9 3.6 7.3 2.8 3.0 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding Fib_alpha PF08702.5 CDI87818.1 - 3.3 7.8 24.3 0.69 10.0 1.8 2.7 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family CDC37_N PF03234.9 CDI87818.1 - 3.4 7.9 24.7 4.3 7.6 12.9 2.3 1 1 1 2 2 2 0 Cdc37 N terminal kinase binding COG2 PF06148.6 CDI87818.1 - 4.9 7.0 16.9 0.73 9.7 5.0 3.0 2 1 2 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF641 PF04859.7 CDI87818.1 - 6.9 6.4 22.6 1.1 9.0 1.4 3.3 1 1 2 3 3 3 0 Plant protein of unknown function (DUF641) Spc7 PF08317.6 CDI87818.1 - 7.3 5.1 31.9 0.025 13.2 8.5 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein Glyoxalase PF00903.20 CDI87819.1 - 8e-11 42.0 0.0 6.4e-08 32.6 0.0 3.0 2 1 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 CDI87819.1 - 1.9e-10 41.2 0.1 8.6e-07 29.5 0.0 3.6 2 1 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_4 PF13669.1 CDI87819.1 - 9.8e-05 22.3 0.0 0.046 13.7 0.0 2.5 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily HoxA13_N PF12284.3 CDI87820.1 - 6.7 6.8 7.3 15 5.7 0.8 2.5 2 0 0 2 2 2 0 Hox protein A13 N terminal gag-asp_proteas PF13975.1 CDI87821.1 - 4.8e-09 35.9 0.1 1.1e-08 34.8 0.1 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 CDI87821.1 - 1.5e-06 28.6 0.0 3.5e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease RVT_1 PF00078.22 CDI87821.1 - 0.00017 21.0 0.0 0.0011 18.3 0.0 1.9 1 1 1 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP PF00077.15 CDI87821.1 - 0.023 14.6 0.0 0.068 13.0 0.0 1.8 1 0 0 1 1 1 0 Retroviral aspartyl protease DUF1758 PF05585.7 CDI87821.1 - 0.023 14.2 0.0 0.053 13.0 0.0 1.5 1 0 0 1 1 1 0 Putative peptidase (DUF1758) Asp_protease PF09668.5 CDI87821.1 - 0.033 13.7 0.0 0.17 11.4 0.0 2.0 2 0 0 2 2 2 0 Aspartyl protease PAT1 PF09770.4 CDI87822.1 - 0.0013 17.1 37.7 0.0013 17.0 26.1 1.2 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 Hid1 PF12722.2 CDI87822.1 - 0.0097 13.6 10.1 0.0094 13.6 7.0 1.0 1 0 0 1 1 1 1 High-temperature-induced dauer-formation protein SAGA-Tad1 PF12767.2 CDI87822.1 - 0.031 13.9 14.5 0.042 13.4 10.1 1.4 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit Band_3_cyto PF07565.8 CDI87822.1 - 0.21 11.0 15.3 0.14 11.6 9.6 1.3 2 0 0 2 2 2 0 Band 3 cytoplasmic domain Ycf1 PF05758.7 CDI87822.1 - 0.88 7.2 9.6 0.87 7.2 6.6 1.1 1 0 0 1 1 1 0 Ycf1 Herpes_UL87 PF03043.9 CDI87822.1 - 2.2 6.5 4.8 2.5 6.3 3.3 1.2 1 0 0 1 1 1 0 Herpesvirus UL87 family Herpes_env PF01673.13 CDI87822.1 - 2.9 6.3 11.3 3.5 6.0 7.9 1.1 1 0 0 1 1 1 0 Herpesvirus putative major envelope glycoprotein CDK5_activator PF03261.10 CDI87822.1 - 3 7.1 10.1 4 6.6 7.0 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein Het-C PF07217.6 CDI87822.1 - 3.2 5.8 9.9 3.8 5.6 6.9 1.1 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C CPSF100_C PF13299.1 CDI87822.1 - 7.4 6.7 12.9 3.2 7.9 7.4 1.5 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal IncA PF04156.9 CDI87823.1 - 0.0022 17.6 0.3 0.0025 17.4 0.2 1.2 1 0 0 1 1 1 1 IncA protein Claudin_2 PF13903.1 CDI87823.1 - 1.1 8.9 7.8 1.4 8.5 5.4 1.1 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction RAB3GAP2_N PF14655.1 CDI87823.1 - 1.5 7.7 8.2 1.7 7.5 5.7 1.0 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus DUF3729 PF12526.3 CDI87823.1 - 7.9 7.8 7.2 11 7.4 5.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3729) G-gamma PF00631.17 CDI87824.1 - 0.11 12.2 7.0 0.92 9.2 0.2 2.8 3 0 0 3 3 3 0 GGL domain GCFC PF07842.7 CDI87825.1 - 3.8e-18 65.8 42.5 1.7e-15 57.1 14.3 4.8 3 2 1 4 4 4 2 GC-rich sequence DNA-binding factor-like protein Med15 PF09606.5 CDI87825.1 - 0.0023 16.2 14.0 0.0023 16.2 9.7 4.4 4 0 0 4 4 4 2 ARC105 or Med15 subunit of Mediator complex non-fungal Pex14_N PF04695.8 CDI87825.1 - 0.0067 16.4 0.2 0.0067 16.4 0.1 8.7 6 3 1 7 7 7 3 Peroxisomal membrane anchor protein (Pex14p) conserved region Mucin PF01456.12 CDI87825.1 - 0.0079 15.9 4.1 0.0079 15.9 2.8 4.4 4 1 0 4 4 4 1 Mucin-like glycoprotein SPX PF03105.14 CDI87825.1 - 3.8 7.2 44.1 0.83 9.3 1.3 4.3 4 0 0 4 4 4 0 SPX domain Ribosomal_L13 PF00572.13 CDI87826.1 - 3e-16 59.6 0.8 5.2e-16 58.8 0.1 1.7 2 0 0 2 2 2 1 Ribosomal protein L13 IncA PF04156.9 CDI87827.1 - 1.2e-05 25.0 11.7 1.7e-05 24.5 8.1 1.2 1 0 0 1 1 1 1 IncA protein CD20 PF04103.10 CDI87827.1 - 0.0015 18.4 1.0 0.002 18.0 0.7 1.3 1 1 0 1 1 1 1 CD20-like family Activator_LAG-3 PF11498.3 CDI87827.1 - 0.0035 16.1 28.5 0.0037 16.0 19.8 1.1 1 0 0 1 1 1 1 Transcriptional activator LAG-3 Med15 PF09606.5 CDI87827.1 - 0.01 14.0 39.3 0.012 13.8 27.2 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal GBP_C PF02841.9 CDI87827.1 - 0.036 13.2 18.1 0.042 13.0 12.6 1.0 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain V_ATPase_I PF01496.14 CDI87827.1 - 0.042 11.7 3.0 0.042 11.7 2.1 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family FHIPEP PF00771.15 CDI87827.1 - 0.047 12.0 8.7 0.049 11.9 6.0 1.1 1 0 0 1 1 1 0 FHIPEP family FimP PF09766.4 CDI87827.1 - 0.059 12.4 14.5 0.062 12.3 10.1 1.0 1 0 0 1 1 1 0 Fms-interacting protein ADP_ribosyl_GH PF03747.9 CDI87827.1 - 0.063 13.0 12.9 0.077 12.7 8.9 1.1 1 0 0 1 1 1 0 ADP-ribosylglycohydrolase Suf PF05843.9 CDI87827.1 - 0.066 12.9 12.3 0.073 12.7 8.5 1.0 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Claudin_2 PF13903.1 CDI87827.1 - 0.1 12.3 13.6 0.2 11.3 9.5 1.5 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction DUF4446 PF14584.1 CDI87827.1 - 0.12 12.1 4.4 0.13 12.0 3.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) DUF4557 PF15101.1 CDI87827.1 - 0.13 12.1 16.1 0.14 11.9 11.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) SDF PF00375.13 CDI87827.1 - 0.16 10.7 4.4 0.23 10.2 3.0 1.3 1 1 0 1 1 1 0 Sodium:dicarboxylate symporter family DUF3450 PF11932.3 CDI87827.1 - 0.17 11.1 31.0 0.19 10.9 21.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) FAM60A PF15396.1 CDI87827.1 - 0.21 11.3 3.5 0.22 11.2 2.4 1.1 1 0 0 1 1 1 0 Protein Family FAM60A Spt20 PF12090.3 CDI87827.1 - 0.21 10.9 7.8 0.27 10.5 5.4 1.4 1 0 0 1 1 1 0 Spt20 family DUF4231 PF14015.1 CDI87827.1 - 0.21 11.5 10.9 0.25 11.3 7.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4231) VIT1 PF01988.14 CDI87827.1 - 0.23 10.9 7.6 0.33 10.4 5.3 1.3 1 0 0 1 1 1 0 VIT family IPP-2 PF04979.9 CDI87827.1 - 0.27 11.4 5.3 0.32 11.2 3.7 1.2 1 0 0 1 1 1 0 Protein phosphatase inhibitor 2 (IPP-2) HemX PF04375.9 CDI87827.1 - 0.28 9.7 30.7 0.33 9.5 21.3 1.0 1 0 0 1 1 1 0 HemX DUF2232 PF09991.4 CDI87827.1 - 0.33 9.9 7.1 0.38 9.7 4.9 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) DUF897 PF05982.7 CDI87827.1 - 0.4 9.4 10.2 0.48 9.1 7.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF897) TFIIA PF03153.8 CDI87827.1 - 0.47 10.3 27.4 0.54 10.0 19.0 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF913 PF06025.7 CDI87827.1 - 0.47 9.1 6.5 0.49 9.0 4.5 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) OATP PF03137.15 CDI87827.1 - 0.52 8.3 4.0 0.47 8.4 2.8 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family RAB3GAP2_N PF14655.1 CDI87827.1 - 0.53 9.2 11.1 0.76 8.7 7.7 1.3 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Chloroa_b-bind PF00504.16 CDI87827.1 - 0.55 10.4 6.2 0.66 10.2 4.3 1.1 1 0 0 1 1 1 0 Chlorophyll A-B binding protein Bac_luciferase PF00296.15 CDI87827.1 - 0.56 9.2 13.4 0.61 9.1 9.3 1.0 1 0 0 1 1 1 0 Luciferase-like monooxygenase FAM222A PF15258.1 CDI87827.1 - 0.67 9.1 18.1 0.82 8.8 12.6 1.1 1 0 0 1 1 1 0 Protein family of FAM222A Trp_oprn_chp PF09534.5 CDI87827.1 - 0.67 9.5 19.1 0.99 8.9 13.2 1.2 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Gastrin PF00918.12 CDI87827.1 - 0.67 10.7 16.7 0.95 10.2 11.6 1.3 1 0 0 1 1 1 0 Gastrin/cholecystokinin family AAA_23 PF13476.1 CDI87827.1 - 0.69 10.1 10.9 0.73 10.1 7.6 1.1 1 0 0 1 1 1 0 AAA domain PAT1 PF09770.4 CDI87827.1 - 0.81 7.8 27.4 0.93 7.6 19.0 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF4207 PF13904.1 CDI87827.1 - 0.81 9.0 19.4 0.99 8.7 13.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4207) Hamartin PF04388.7 CDI87827.1 - 1.1 7.8 11.7 1.2 7.6 8.1 1.0 1 0 0 1 1 1 0 Hamartin protein FLO_LFY PF01698.11 CDI87827.1 - 1.1 8.0 9.7 1.2 7.8 6.7 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein DUF106 PF01956.11 CDI87827.1 - 1.2 8.6 5.8 1.2 8.6 4.0 1.2 1 0 0 1 1 1 0 Integral membrane protein DUF106 Baculo_PP31 PF05311.6 CDI87827.1 - 1.2 8.3 8.3 1.3 8.2 5.7 1.1 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) YfhO PF09586.5 CDI87827.1 - 1.4 6.8 7.3 1.6 6.6 5.1 1.0 1 0 0 1 1 1 0 Bacterial membrane protein YfhO Myco_19_kDa PF05481.7 CDI87827.1 - 1.4 8.7 12.3 1.7 8.4 8.5 1.1 1 0 0 1 1 1 0 Mycobacterium 19 kDa lipoprotein antigen Serinc PF03348.10 CDI87827.1 - 1.5 7.4 9.5 1.7 7.2 6.6 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) Gag_spuma PF03276.9 CDI87827.1 - 1.7 6.8 18.1 1.9 6.7 12.6 1.1 1 0 0 1 1 1 0 Spumavirus gag protein DDHD PF02862.12 CDI87827.1 - 2.2 8.0 7.1 2.4 7.9 4.9 1.1 1 0 0 1 1 1 0 DDHD domain Spc24 PF08286.6 CDI87827.1 - 2.3 7.9 9.8 3.1 7.5 6.8 1.2 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 Spore_coat_CotO PF14153.1 CDI87827.1 - 2.4 7.5 14.8 2.7 7.3 10.3 1.1 1 0 0 1 1 1 0 Spore coat protein CotO HAUS6_N PF14661.1 CDI87827.1 - 2.5 7.3 18.5 3 7.1 12.8 1.0 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Peptidase_S15 PF02129.13 CDI87827.1 - 2.5 7.4 13.0 3 7.1 9.0 1.0 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) DcuC PF03606.10 CDI87827.1 - 2.5 6.2 9.1 2.9 5.9 6.3 1.0 1 0 0 1 1 1 0 C4-dicarboxylate anaerobic carrier DUF3260 PF11658.3 CDI87827.1 - 2.6 6.0 13.6 2.8 5.9 9.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3260) FNIP_N PF14636.1 CDI87827.1 - 2.8 8.4 10.6 3.3 8.2 7.4 1.1 1 0 0 1 1 1 0 Folliculin-interacting protein N-terminus DivIC PF04977.10 CDI87827.1 - 2.9 7.4 19.1 4.9 6.7 13.2 1.4 1 0 0 1 1 1 0 Septum formation initiator Helicase_RecD PF05127.9 CDI87827.1 - 3.1 7.4 10.9 4.4 6.9 7.6 1.3 1 0 0 1 1 1 0 Helicase DUF2894 PF11445.3 CDI87827.1 - 3.3 7.9 22.0 4 7.6 15.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2894) DUF1980 PF09323.5 CDI87827.1 - 3.6 7.2 7.5 5.2 6.7 5.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) Herpes_UL87 PF03043.9 CDI87827.1 - 3.7 5.8 8.8 4.2 5.6 6.1 1.0 1 0 0 1 1 1 0 Herpesvirus UL87 family DUF3357 PF11837.3 CDI87827.1 - 3.9 7.3 5.6 7.6 6.4 3.4 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF3357) Band_3_cyto PF07565.8 CDI87827.1 - 4.4 6.7 9.8 4.9 6.6 6.8 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain DUF3371 PF11851.3 CDI87827.1 - 4.5 7.9 16.0 6.3 7.4 11.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3371) FliP PF00813.15 CDI87827.1 - 4.9 6.8 6.9 5.1 6.7 4.8 1.1 1 0 0 1 1 1 0 FliP family Med13_N PF11597.3 CDI87827.1 - 7.8 5.0 14.1 8.9 4.8 9.8 1.2 1 0 0 1 1 1 0 Mediator complex subunit 13 N-terminal MDFI PF15316.1 CDI87827.1 - 8.2 6.3 8.5 9.6 6.1 5.9 1.1 1 0 0 1 1 1 0 MyoD family inhibitor Presenilin PF01080.12 CDI87827.1 - 8.2 5.1 10.9 9.3 4.9 7.6 1.0 1 0 0 1 1 1 0 Presenilin Aminotran_1_2 PF00155.16 CDI87827.1 - 8.8 5.1 14.3 11 4.7 9.9 1.3 1 1 0 1 1 1 0 Aminotransferase class I and II Glt_symporter PF03616.9 CDI87827.1 - 9.4 4.6 7.0 11 4.4 4.8 1.1 1 0 0 1 1 1 0 Sodium/glutamate symporter DUF4611 PF15387.1 CDI87828.1 - 0.0039 17.3 0.6 0.0069 16.5 0.4 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4611) DUF4316 PF14195.1 CDI87828.1 - 0.027 14.5 0.6 0.051 13.6 0.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4316) MRP-S31 PF15433.1 CDI87828.1 - 0.23 10.8 6.3 0.28 10.5 4.4 1.1 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 Peptidase_M20 PF01546.23 CDI87828.1 - 0.36 10.3 0.0 0.36 10.3 0.0 2.2 2 1 0 2 2 2 0 Peptidase family M20/M25/M40 Sporozoite_P67 PF05642.6 CDI87828.1 - 0.85 7.4 13.3 1.1 6.9 9.2 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen PHD_3 PF13922.1 CDI87828.1 - 1.4 9.1 5.9 3.4 7.9 4.1 1.6 1 0 0 1 1 1 0 PHD domain of transcriptional enhancer, Asx Auxin_repressed PF05564.7 CDI87828.1 - 4.2 8.0 7.4 0.18 12.3 1.1 1.7 2 0 0 2 2 2 0 Dormancy/auxin associated protein Med3 PF11593.3 CDI87829.1 - 0.005 16.1 3.2 0.005 16.1 2.2 7.9 5 1 1 6 6 6 2 Mediator complex subunit 3 fungal DUF1777 PF08648.7 CDI87829.1 - 4.1 7.0 48.2 0.18 11.5 20.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1777) Ribosomal_60s PF00428.14 CDI87830.1 - 0.023 15.0 34.9 0.098 13.0 6.5 2.4 2 0 0 2 2 2 0 60s Acidic ribosomal protein DUF2681 PF10883.3 CDI87830.1 - 5.2 7.3 13.2 0.93 9.7 3.8 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) Ribosomal_60s PF00428.14 CDI87835.1 - 0.012 16.0 8.2 0.012 16.0 5.7 9.4 6 3 2 8 8 8 0 60s Acidic ribosomal protein DUF1510 PF07423.6 CDI87837.1 - 3.1e-05 23.4 8.7 3.1e-05 23.4 6.0 1.5 2 0 0 2 2 1 1 Protein of unknown function (DUF1510) DUF3260 PF11658.3 CDI87837.1 - 4.1e-05 21.9 10.8 4.7e-05 21.7 7.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3260) YfhO PF09586.5 CDI87837.1 - 0.0002 19.5 12.1 0.00028 19.0 8.4 1.2 1 0 0 1 1 1 1 Bacterial membrane protein YfhO MMR1 PF08505.5 CDI87837.1 - 0.00039 20.5 4.1 0.00039 20.5 2.8 1.1 1 0 0 1 1 1 1 Mitochondrial Myo2 receptor-related protein SpoIIIAH PF12685.2 CDI87837.1 - 0.0011 18.5 6.1 0.0011 18.5 4.2 2.1 2 0 0 2 2 1 1 SpoIIIAH-like protein Spore_YhcN_YlaJ PF09580.5 CDI87837.1 - 0.0019 18.3 0.3 0.0019 18.3 0.2 1.1 1 0 0 1 1 1 1 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) Ycf1 PF05758.7 CDI87837.1 - 0.0022 15.7 9.0 0.0024 15.6 6.2 1.1 1 0 0 1 1 1 1 Ycf1 Suf PF05843.9 CDI87837.1 - 0.0024 17.6 6.1 0.0024 17.6 4.2 1.1 1 0 0 1 1 1 1 Suppressor of forked protein (Suf) 7tm_7 PF08395.7 CDI87837.1 - 0.0028 16.7 17.6 0.0036 16.4 12.2 1.3 1 0 0 1 1 1 1 7tm Chemosensory receptor Mem_trans PF03547.13 CDI87837.1 - 0.0054 15.0 4.7 0.0069 14.7 3.2 1.2 1 0 0 1 1 1 1 Membrane transport protein DUF1980 PF09323.5 CDI87837.1 - 0.012 15.3 5.9 0.012 15.3 4.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) Shisa PF13908.1 CDI87837.1 - 0.016 15.3 5.5 0.023 14.8 3.8 1.2 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Wzy_C PF04932.10 CDI87837.1 - 0.018 14.8 0.0 0.025 14.3 0.0 1.2 1 0 0 1 1 1 0 O-Antigen ligase NicO PF03824.11 CDI87837.1 - 0.025 13.8 8.3 0.038 13.2 5.7 1.3 1 1 0 1 1 1 0 High-affinity nickel-transport protein DUF4512 PF14975.1 CDI87837.1 - 0.025 15.3 1.9 0.052 14.3 1.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4512) Peptidase_M50B PF13398.1 CDI87837.1 - 0.045 13.1 9.1 0.056 12.8 6.3 1.1 1 0 0 1 1 1 0 Peptidase M50B-like Herpes_LMP1 PF05297.6 CDI87837.1 - 0.057 12.3 10.4 0.082 11.8 7.2 1.2 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) Neur_chan_memb PF02932.11 CDI87837.1 - 0.066 13.0 4.9 0.1 12.5 3.4 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF2052 PF09747.4 CDI87837.1 - 0.11 12.4 15.8 0.17 11.7 11.0 1.3 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) Neur PF00064.13 CDI87837.1 - 0.14 10.2 2.4 0.16 9.9 1.7 1.2 1 0 0 1 1 1 0 Neuraminidase Stig1 PF04885.8 CDI87837.1 - 0.16 12.1 4.9 0.29 11.3 3.4 1.4 1 0 0 1 1 1 0 Stigma-specific protein, Stig1 RIC3 PF15361.1 CDI87837.1 - 0.21 11.8 11.8 0.036 14.2 5.8 1.4 2 0 0 2 2 1 0 Resistance to inhibitors of cholinesterase homologue 3 Endonuc_Holl PF10107.4 CDI87837.1 - 0.22 11.1 14.8 0.39 10.3 10.2 1.4 1 0 0 1 1 1 0 Endonuclease related to archaeal Holliday junction resolvase OmpH PF03938.9 CDI87837.1 - 0.24 11.3 26.1 0.27 11.1 18.1 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Folate_carrier PF01770.13 CDI87837.1 - 0.24 9.8 19.2 0.15 10.4 12.2 1.4 1 1 0 1 1 1 0 Reduced folate carrier ATG22 PF11700.3 CDI87837.1 - 0.27 9.6 5.0 0.45 8.9 3.4 1.4 1 1 0 1 1 1 0 Vacuole effluxer Atg22 like BORG_CEP PF14957.1 CDI87837.1 - 0.29 12.0 7.3 0.4 11.5 5.0 1.2 1 0 0 1 1 1 0 Cdc42 effector Peptidase_S49_N PF08496.5 CDI87837.1 - 0.35 10.6 19.6 0.13 12.0 11.9 1.5 1 1 0 1 1 1 0 Peptidase family S49 N-terminal DUF2370 PF10176.4 CDI87837.1 - 0.38 10.0 4.2 0.65 9.2 2.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) FAM163 PF15069.1 CDI87837.1 - 0.53 10.8 4.5 1.2 9.7 3.1 1.5 1 0 0 1 1 1 0 FAM163 family DUF4131 PF13567.1 CDI87837.1 - 0.83 9.0 18.3 3.9 6.8 12.7 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4131) RP-C_C PF11800.3 CDI87837.1 - 1.2 8.7 11.5 1.6 8.3 8.0 1.1 1 0 0 1 1 1 0 Replication protein C C-terminal region Gastrin PF00918.12 CDI87837.1 - 1.3 9.8 16.0 3.1 8.6 11.1 1.7 1 0 0 1 1 1 0 Gastrin/cholecystokinin family SpoVR PF04293.8 CDI87837.1 - 1.3 7.2 14.4 1.7 6.9 10.0 1.1 1 0 0 1 1 1 0 SpoVR like protein DUF3381 PF11861.3 CDI87837.1 - 1.4 8.4 20.1 2.4 7.6 13.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) YqfQ PF14181.1 CDI87837.1 - 1.4 8.9 16.5 2.3 8.2 11.4 1.3 1 0 0 1 1 1 0 YqfQ-like protein TCP PF03634.8 CDI87837.1 - 1.5 9.2 18.7 2.1 8.7 13.0 1.2 1 0 0 1 1 1 0 TCP family transcription factor UPF0565 PF10561.4 CDI87837.1 - 1.6 7.5 11.0 2.5 6.8 7.6 1.3 1 0 0 1 1 1 0 Uncharacterised protein family UPF0565 RED_N PF07808.8 CDI87837.1 - 1.6 7.8 24.3 2.5 7.2 16.8 1.3 1 0 0 1 1 1 0 RED-like protein N-terminal region SelP_N PF04592.9 CDI87837.1 - 1.6 8.0 17.1 2.2 7.6 11.9 1.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region FAM176 PF14851.1 CDI87837.1 - 1.8 8.2 12.2 0.04 13.5 2.8 2.0 2 0 0 2 2 2 0 FAM176 family AIF_C PF14721.1 CDI87837.1 - 1.9 8.7 10.7 2.8 8.2 7.4 1.2 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term SID-1_RNA_chan PF13965.1 CDI87837.1 - 1.9 6.5 15.5 5.4 5.0 10.7 1.7 1 1 0 1 1 1 0 dsRNA-gated channel SID-1 DUF3810 PF12725.2 CDI87837.1 - 1.9 7.2 9.7 2.4 6.9 6.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) Tim54 PF11711.3 CDI87837.1 - 2.1 6.8 11.7 2.6 6.5 8.1 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Pex14_N PF04695.8 CDI87837.1 - 2.3 8.2 15.6 3.5 7.6 10.8 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Pex24p PF06398.6 CDI87837.1 - 2.4 6.8 10.6 7.7 5.1 7.3 1.9 1 1 0 1 1 1 0 Integral peroxisomal membrane peroxin Herpes_DNAp_acc PF04929.7 CDI87837.1 - 2.8 6.7 13.7 3.8 6.3 9.5 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor SeqA PF03925.8 CDI87837.1 - 3 7.5 13.4 5.4 6.6 9.3 1.4 1 0 0 1 1 1 0 SeqA protein DUF4094 PF13334.1 CDI87837.1 - 3.8 7.9 14.2 13 6.2 9.9 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4094) Nucleoside_tran PF01733.13 CDI87837.1 - 4 6.5 11.3 6 5.9 7.5 1.5 1 1 1 2 2 2 0 Nucleoside transporter Gti1_Pac2 PF09729.4 CDI87837.1 - 4.1 7.2 10.5 6.1 6.6 7.2 1.2 1 0 0 1 1 1 0 Gti1/Pac2 family Glyco_transf_15 PF01793.11 CDI87837.1 - 4.2 6.2 14.7 5.7 5.7 10.2 1.1 1 0 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase DUF2126 PF09899.4 CDI87837.1 - 4.4 5.2 12.9 5.6 4.8 9.0 1.0 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) DDHD PF02862.12 CDI87837.1 - 9.3 5.9 15.4 13 5.4 10.7 1.2 1 0 0 1 1 1 0 DDHD domain SR-25 PF10500.4 CDI87838.1 - 4.6e-05 23.0 3.9 4.6e-05 23.0 2.7 8.0 6 2 0 6 6 6 3 Nuclear RNA-splicing-associated protein Peptidase_S41 PF03572.13 CDI87838.1 - 0.018 14.4 0.2 0.17 11.3 0.0 2.5 2 0 0 2 2 2 0 Peptidase family S41 DUF4366 PF14283.1 CDI87838.1 - 3.3 7.0 17.5 0.067 12.6 0.4 3.8 3 1 0 3 3 3 0 Domain of unknown function (DUF4366) Ribosomal_S9 PF00380.14 CDI87839.1 - 0.0022 18.2 2.3 0.0022 18.2 1.6 1.9 1 1 1 2 2 1 1 Ribosomal protein S9/S16 PAT1 PF09770.4 CDI87839.1 - 0.0048 15.2 29.7 0.0041 15.4 20.6 1.0 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 SprA-related PF12118.3 CDI87839.1 - 0.0065 15.8 31.3 0.0067 15.7 21.7 1.1 1 0 0 1 1 1 1 SprA-related family Suf PF05843.9 CDI87839.1 - 0.012 15.3 16.9 0.015 15.0 11.7 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Raftlin PF15250.1 CDI87839.1 - 0.014 13.9 10.1 0.013 14.0 7.0 1.0 1 0 0 1 1 1 0 Raftlin Pex14_N PF04695.8 CDI87839.1 - 0.03 14.3 20.2 0.038 14.0 14.0 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region RR_TM4-6 PF06459.7 CDI87839.1 - 0.032 14.1 11.3 0.031 14.1 7.8 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF913 PF06025.7 CDI87839.1 - 0.04 12.6 3.9 0.04 12.6 2.7 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) FimP PF09766.4 CDI87839.1 - 0.046 12.7 25.6 0.056 12.5 17.7 1.1 1 0 0 1 1 1 0 Fms-interacting protein Peroxin-13_N PF04088.8 CDI87839.1 - 0.048 13.6 3.1 0.052 13.4 2.2 1.3 1 0 0 1 1 1 0 Peroxin 13, N-terminal region PH_4 PF15404.1 CDI87839.1 - 0.052 13.0 9.2 0.06 12.8 6.4 1.1 1 0 0 1 1 1 0 Pleckstrin homology domain Med15 PF09606.5 CDI87839.1 - 0.058 11.6 47.4 0.05 11.8 32.9 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF4175 PF13779.1 CDI87839.1 - 0.071 10.8 44.0 0.067 10.8 30.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) TFIIA PF03153.8 CDI87839.1 - 0.088 12.6 23.8 0.09 12.6 16.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4159 PF13709.1 CDI87839.1 - 0.11 11.5 4.9 0.32 10.0 3.4 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4159) Kei1 PF08552.6 CDI87839.1 - 0.13 11.8 8.7 0.16 11.5 6.0 1.1 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 Band_3_cyto PF07565.8 CDI87839.1 - 0.13 11.7 12.9 0.14 11.6 9.0 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain SeqA PF03925.8 CDI87839.1 - 0.14 11.8 9.5 0.15 11.7 6.6 1.1 1 0 0 1 1 1 0 SeqA protein CPSF100_C PF13299.1 CDI87839.1 - 0.14 12.3 9.0 0.16 12.1 6.2 1.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Paf1 PF03985.8 CDI87839.1 - 0.15 10.8 18.4 0.17 10.6 12.8 1.0 1 0 0 1 1 1 0 Paf1 Gti1_Pac2 PF09729.4 CDI87839.1 - 0.15 11.9 8.2 0.16 11.7 5.7 1.1 1 0 0 1 1 1 0 Gti1/Pac2 family Pox_Ag35 PF03286.9 CDI87839.1 - 0.15 11.5 9.2 0.18 11.3 6.3 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein FLO_LFY PF01698.11 CDI87839.1 - 0.18 10.6 13.0 0.18 10.6 9.0 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein DDHD PF02862.12 CDI87839.1 - 0.2 11.4 13.9 0.23 11.2 9.6 1.1 1 0 0 1 1 1 0 DDHD domain SAPS PF04499.10 CDI87839.1 - 0.2 10.2 10.1 0.22 10.1 7.0 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein AIF_C PF14721.1 CDI87839.1 - 0.21 11.8 11.7 0.28 11.4 8.1 1.1 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term RNA_pol_Rpc4 PF05132.9 CDI87839.1 - 0.21 11.5 13.2 0.29 11.1 9.1 1.1 1 0 0 1 1 1 0 RNA polymerase III RPC4 FAM60A PF15396.1 CDI87839.1 - 0.22 11.2 9.3 0.23 11.1 6.5 1.1 1 0 0 1 1 1 0 Protein Family FAM60A CMV_1a PF12467.3 CDI87839.1 - 0.22 11.8 7.7 0.27 11.5 5.3 1.1 1 0 0 1 1 1 0 Cucumber mosaic virus 1a protein family DUF912 PF06024.7 CDI87839.1 - 0.22 11.5 11.0 0.39 10.7 7.6 1.4 1 1 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) NPR3 PF03666.8 CDI87839.1 - 0.25 9.8 12.9 0.29 9.6 8.9 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 IncA PF04156.9 CDI87839.1 - 0.27 10.8 23.0 0.26 10.8 15.9 1.1 1 0 0 1 1 1 0 IncA protein AUX_IAA PF02309.11 CDI87839.1 - 0.27 10.9 10.1 0.29 10.8 7.0 1.1 1 0 0 1 1 1 0 AUX/IAA family MDFI PF15316.1 CDI87839.1 - 0.29 11.1 6.5 0.29 11.1 4.5 1.1 1 0 0 1 1 1 0 MyoD family inhibitor Zip PF02535.17 CDI87839.1 - 0.3 10.0 4.7 0.34 9.8 3.2 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter Gag_spuma PF03276.9 CDI87839.1 - 0.3 9.3 35.0 0.31 9.3 24.2 1.0 1 0 0 1 1 1 0 Spumavirus gag protein Rtf2 PF04641.7 CDI87839.1 - 0.31 10.1 13.4 0.36 9.9 9.3 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger Glyco_transf_15 PF01793.11 CDI87839.1 - 0.38 9.6 14.1 0.41 9.5 9.8 1.0 1 0 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase AAA_23 PF13476.1 CDI87839.1 - 0.46 10.7 18.3 0.51 10.6 12.7 1.1 1 0 0 1 1 1 0 AAA domain Dala_Dala_lig_N PF01820.16 CDI87839.1 - 0.47 10.7 5.6 0.61 10.4 3.9 1.3 1 0 0 1 1 1 0 D-ala D-ala ligase N-terminus DUF3408 PF11888.3 CDI87839.1 - 0.51 10.2 12.3 0.6 10.0 8.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) RIC3 PF15361.1 CDI87839.1 - 0.53 10.5 14.6 0.69 10.1 10.2 1.2 1 0 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 DHHW PF14286.1 CDI87839.1 - 0.53 9.5 8.8 0.59 9.4 6.1 1.0 1 0 0 1 1 1 0 DHHW protein DUF605 PF04652.11 CDI87839.1 - 0.54 9.5 18.9 0.61 9.4 13.1 1.0 1 0 0 1 1 1 0 Vta1 like Peptidase_S49_N PF08496.5 CDI87839.1 - 0.57 9.9 12.5 0.83 9.4 8.7 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal SpoIIP PF07454.6 CDI87839.1 - 0.58 9.2 10.8 0.66 9.0 7.5 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Baculo_PP31 PF05311.6 CDI87839.1 - 0.59 9.3 13.9 0.63 9.2 9.6 1.1 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) BORG_CEP PF14957.1 CDI87839.1 - 0.61 11.0 8.5 0.7 10.8 5.9 1.1 1 0 0 1 1 1 0 Cdc42 effector Cyto_heme_lyase PF01265.12 CDI87839.1 - 0.63 9.5 12.3 0.62 9.6 8.5 1.0 1 0 0 1 1 1 0 Cytochrome c/c1 heme lyase FNIP_N PF14636.1 CDI87839.1 - 0.64 10.5 14.8 0.73 10.3 10.3 1.1 1 0 0 1 1 1 0 Folliculin-interacting protein N-terminus DUF4407 PF14362.1 CDI87839.1 - 0.67 8.8 19.4 0.68 8.8 13.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) eIF-3_zeta PF05091.7 CDI87839.1 - 0.7 8.4 23.0 0.73 8.3 16.0 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF3449 PF11931.3 CDI87839.1 - 0.71 9.3 14.1 0.86 9.0 9.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3449) SAGA-Tad1 PF12767.2 CDI87839.1 - 0.82 9.2 21.8 0.87 9.1 15.1 1.1 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit F-protein PF00469.15 CDI87839.1 - 0.89 8.8 13.3 1.1 8.6 9.2 1.1 1 0 0 1 1 1 0 Negative factor, (F-Protein) or Nef Dynamin_N PF00350.18 CDI87839.1 - 0.94 9.2 7.7 1.1 9.1 5.3 1.1 1 0 0 1 1 1 0 Dynamin family CobT PF06213.7 CDI87839.1 - 0.99 8.4 12.5 1.2 8.2 8.7 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF3043 PF11241.3 CDI87839.1 - 1.1 8.8 16.1 1.7 8.2 11.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) DUF4366 PF14283.1 CDI87839.1 - 1.1 8.6 8.9 1.7 7.9 6.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) Neur_chan_memb PF02932.11 CDI87839.1 - 1.2 9.0 8.6 1.3 8.8 5.9 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Ycf1 PF05758.7 CDI87839.1 - 1.2 6.7 14.1 1.3 6.6 9.8 1.0 1 0 0 1 1 1 0 Ycf1 DUF4355 PF14265.1 CDI87839.1 - 1.3 9.0 23.4 1.6 8.6 16.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4355) PPP4R2 PF09184.6 CDI87839.1 - 1.3 8.4 12.1 1.5 8.3 8.4 1.0 1 0 0 1 1 1 0 PPP4R2 Peptidase_S15 PF02129.13 CDI87839.1 - 1.3 8.3 9.7 1.4 8.2 6.7 1.1 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) NARP1 PF12569.3 CDI87839.1 - 1.3 7.6 17.5 1.5 7.4 12.1 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Presenilin PF01080.12 CDI87839.1 - 1.3 7.7 7.3 1.4 7.6 5.1 1.1 1 0 0 1 1 1 0 Presenilin CD20 PF04103.10 CDI87839.1 - 1.3 8.8 4.0 1.7 8.5 2.7 1.3 1 0 0 1 1 1 0 CD20-like family Ndc1_Nup PF09531.5 CDI87839.1 - 1.4 7.2 10.4 1.4 7.2 7.2 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup FAM176 PF14851.1 CDI87839.1 - 1.5 8.4 8.5 2.2 7.9 5.9 1.3 1 0 0 1 1 1 0 FAM176 family Serinc PF03348.10 CDI87839.1 - 1.6 7.3 13.8 1.7 7.2 9.6 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) Hid1 PF12722.2 CDI87839.1 - 1.7 6.2 15.7 1.8 6.1 10.9 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein OATP PF03137.15 CDI87839.1 - 1.8 6.5 13.7 2.2 6.2 9.5 1.0 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Cellulose_synt PF03552.9 CDI87839.1 - 1.8 6.7 6.8 1.8 6.7 4.7 1.0 1 0 0 1 1 1 0 Cellulose synthase Paramyxo_ncap PF00973.14 CDI87839.1 - 1.9 7.1 10.6 1.9 7.1 7.3 1.0 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein PIH1 PF08190.7 CDI87839.1 - 1.9 7.8 20.1 2.4 7.5 13.9 1.1 1 0 0 1 1 1 0 pre-RNA processing PIH1/Nop17 ATAD4 PF15321.1 CDI87839.1 - 2 9.4 15.6 3.4 8.7 10.8 1.5 1 0 0 1 1 1 0 ATPase family AAA domain containing 4 Spore_coat_CotO PF14153.1 CDI87839.1 - 2.1 7.7 24.1 2.6 7.4 16.7 1.1 1 0 0 1 1 1 0 Spore coat protein CotO DUF1764 PF08576.5 CDI87839.1 - 2.1 9.1 19.1 2.9 8.7 13.2 1.3 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) DUF4220 PF13968.1 CDI87839.1 - 2.2 7.3 5.6 2.2 7.2 3.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4220) SpoVR PF04293.8 CDI87839.1 - 2.3 6.5 14.5 2.5 6.3 10.0 1.0 1 0 0 1 1 1 0 SpoVR like protein DUF1088 PF06469.6 CDI87839.1 - 2.3 7.6 11.8 3 7.2 8.2 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1088) Ctr PF04145.10 CDI87839.1 - 2.3 8.2 10.0 3.1 7.8 6.9 1.3 1 0 0 1 1 1 0 Ctr copper transporter family PBP1_TM PF14812.1 CDI87839.1 - 2.4 8.5 14.7 4.1 7.7 10.2 1.5 1 1 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal FYDLN_acid PF09538.5 CDI87839.1 - 2.4 8.7 8.6 3.1 8.4 5.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) DUF4557 PF15101.1 CDI87839.1 - 2.5 7.8 28.7 2.7 7.7 19.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) DUF3464 PF11947.3 CDI87839.1 - 2.5 7.5 14.4 3.1 7.2 10.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) CRF1 PF10380.4 CDI87839.1 - 2.6 8.3 9.7 3.2 8.1 6.7 1.1 1 0 0 1 1 1 0 Transcription factor CRF1 DUF3260 PF11658.3 CDI87839.1 - 2.6 6.0 11.2 2.9 5.9 7.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3260) Spore_YhcN_YlaJ PF09580.5 CDI87839.1 - 2.9 7.9 14.5 3.6 7.6 10.0 1.3 1 0 0 1 1 1 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) Herpes_DNAp_acc PF04929.7 CDI87839.1 - 3.1 6.6 11.4 3 6.7 7.9 1.0 1 0 0 1 1 1 0 Herpes DNA replication accessory factor FMN_dh PF01070.13 CDI87839.1 - 4.2 6.1 7.6 4.6 5.9 5.3 1.0 1 0 0 1 1 1 0 FMN-dependent dehydrogenase DUF2126 PF09899.4 CDI87839.1 - 4.3 5.2 13.5 4.7 5.1 9.4 1.0 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) DUF2058 PF09831.4 CDI87839.1 - 4.4 7.1 29.0 5.3 6.9 20.1 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2058) YABBY PF04690.8 CDI87839.1 - 4.5 7.4 9.8 5.2 7.2 6.8 1.2 1 0 0 1 1 1 0 YABBY protein Anoctamin PF04547.7 CDI87839.1 - 4.6 5.7 9.2 4.6 5.7 6.4 1.1 1 0 0 1 1 1 0 Calcium-activated chloride channel RED_N PF07808.8 CDI87839.1 - 4.9 6.3 24.7 5.3 6.1 17.1 1.1 1 0 0 1 1 1 0 RED-like protein N-terminal region DUF2201_N PF13203.1 CDI87839.1 - 5.1 6.1 18.0 6.3 5.8 12.5 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain Maf1 PF09174.5 CDI87839.1 - 5.2 6.8 9.3 6.2 6.6 6.4 1.1 1 0 0 1 1 1 0 Maf1 regulator Glyco_transf_6 PF03414.8 CDI87839.1 - 5.3 5.3 9.6 6.3 5.1 6.6 1.1 1 0 0 1 1 1 0 Glycosyltransferase family 6 SID-1_RNA_chan PF13965.1 CDI87839.1 - 5.8 4.9 8.4 6 4.9 5.8 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Peptidase_U57 PF05582.7 CDI87839.1 - 6.1 5.7 13.2 7.4 5.4 9.1 1.1 1 0 0 1 1 1 0 YabG peptidase U57 DUF4638 PF15472.1 CDI87839.1 - 6.2 6.3 14.9 6.5 6.2 10.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) G-alpha PF00503.15 CDI87839.1 - 6.3 5.3 17.3 8.2 4.9 12.0 1.0 1 0 0 1 1 1 0 G-protein alpha subunit FHIPEP PF00771.15 CDI87839.1 - 6.4 4.9 10.3 7.2 4.8 7.1 1.2 1 0 0 1 1 1 0 FHIPEP family Hom_end_hint PF05203.11 CDI87839.1 - 6.7 6.3 10.3 8.4 6.0 7.1 1.2 1 0 0 1 1 1 0 Hom_end-associated Hint YjgP_YjgQ PF03739.9 CDI87839.1 - 6.9 5.3 7.9 7.7 5.1 5.4 1.1 1 0 0 1 1 1 0 Predicted permease YjgP/YjgQ family Bud13 PF09736.4 CDI87839.1 - 7.1 6.8 24.9 9.2 6.5 17.3 1.1 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex R_equi_Vir PF05526.6 CDI87839.1 - 7.1 6.2 6.3 8.6 5.9 4.4 1.1 1 0 0 1 1 1 0 Rhodococcus equi virulence-associated protein CDC45 PF02724.9 CDI87839.1 - 7.2 4.5 16.2 7.7 4.4 11.2 1.1 1 0 0 1 1 1 0 CDC45-like protein TraH_2 PF06871.6 CDI87839.1 - 7.3 5.9 8.0 9.1 5.6 5.6 1.1 1 0 0 1 1 1 0 TraH_2 HGTP_anticodon2 PF12745.2 CDI87839.1 - 7.7 5.5 15.3 9.2 5.3 10.6 1.1 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs DUF3675 PF12428.3 CDI87839.1 - 7.9 6.7 7.7 11 6.2 5.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3675) DUF4544 PF15077.1 CDI87839.1 - 8.1 5.8 8.6 8.6 5.7 6.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4544) DDRGK PF09756.4 CDI87839.1 - 8.8 5.6 27.9 11 5.3 19.3 1.1 1 0 0 1 1 1 0 DDRGK domain Mem_trans PF03547.13 CDI87839.1 - 9.6 4.3 9.8 12 4.0 6.8 1.0 1 0 0 1 1 1 0 Membrane transport protein DUF3306 PF11748.3 CDI87839.1 - 9.8 6.8 20.0 15 6.2 13.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3306) TFIIF_alpha PF05793.7 CDI87840.1 - 7.7e-05 21.2 22.0 9.6e-05 20.9 15.3 1.1 1 0 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF755 PF05501.6 CDI87840.1 - 0.036 14.1 27.2 0.33 10.9 6.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF755) Plasmodium_Vir PF05795.6 CDI87840.1 - 0.055 12.6 10.8 0.071 12.3 7.5 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Prog_receptor PF02161.10 CDI87840.1 - 0.074 11.8 13.1 0.093 11.5 9.1 1.2 1 0 0 1 1 1 0 Progesterone receptor DUF2457 PF10446.4 CDI87840.1 - 0.079 11.6 21.5 0.11 11.2 14.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Daxx PF03344.10 CDI87840.1 - 0.16 10.4 23.1 0.21 10.0 16.0 1.1 1 0 0 1 1 1 0 Daxx Family DUF1675 PF07897.6 CDI87840.1 - 0.16 11.8 15.9 0.21 11.4 11.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) Nop53 PF07767.6 CDI87840.1 - 0.16 10.8 29.5 0.2 10.5 20.4 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Mucin PF01456.12 CDI87840.1 - 0.17 11.6 14.9 0.2 11.4 10.3 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein Nop14 PF04147.7 CDI87840.1 - 0.29 8.9 21.7 0.34 8.7 15.1 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 CDI87840.1 - 0.37 8.7 20.9 0.46 8.4 14.5 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF572 PF04502.8 CDI87840.1 - 0.49 9.5 25.9 0.66 9.1 18.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) CENP-T PF15511.1 CDI87840.1 - 0.5 9.5 20.5 0.59 9.3 14.2 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Nucleoplasmin PF03066.10 CDI87840.1 - 0.54 9.7 13.9 0.91 9.0 9.7 1.4 1 0 0 1 1 1 0 Nucleoplasmin Peptidase_S64 PF08192.6 CDI87840.1 - 0.92 7.7 23.0 1.1 7.5 16.0 1.0 1 0 0 1 1 1 0 Peptidase family S64 PIH1 PF08190.7 CDI87840.1 - 0.95 8.8 19.8 1.2 8.4 13.7 1.2 1 0 0 1 1 1 0 pre-RNA processing PIH1/Nop17 Med15 PF09606.5 CDI87840.1 - 1 7.4 18.3 1.6 6.8 12.7 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal NST1 PF13945.1 CDI87840.1 - 1.1 9.3 31.5 0.055 13.5 14.5 2.0 1 1 1 2 2 2 0 Salt tolerance down-regulator RLL PF10036.4 CDI87840.1 - 1.1 8.5 15.7 1.5 8.1 10.9 1.2 1 0 0 1 1 1 0 Putative carnitine deficiency-associated protein Utp14 PF04615.8 CDI87840.1 - 1.2 7.1 29.3 1.5 6.8 20.3 1.0 1 0 0 1 1 1 0 Utp14 protein Ycf1 PF05758.7 CDI87840.1 - 1.9 6.1 16.6 2.3 5.8 11.5 1.1 1 0 0 1 1 1 0 Ycf1 Med19 PF10278.4 CDI87840.1 - 2.5 7.7 17.0 0.38 10.3 8.9 1.6 2 0 0 2 2 2 0 Mediator of RNA pol II transcription subunit 19 DUF1183 PF06682.7 CDI87840.1 - 2.7 7.5 10.8 3.5 7.1 7.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) bHLH-MYC_N PF14215.1 CDI87840.1 - 2.7 8.1 7.2 3.3 7.8 5.0 1.2 1 0 0 1 1 1 0 bHLH-MYC and R2R3-MYB transcription factors N-terminal DUF966 PF06136.8 CDI87840.1 - 2.9 7.2 25.3 3.7 6.8 17.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF966) DUF4175 PF13779.1 CDI87840.1 - 3.4 5.2 23.8 4.2 4.9 16.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Tfb4 PF03850.9 CDI87840.1 - 3.5 6.8 12.2 4.1 6.5 8.5 1.0 1 0 0 1 1 1 0 Transcription factor Tfb4 PLRV_ORF5 PF01690.12 CDI87840.1 - 3.6 6.6 19.9 4.1 6.4 13.8 1.0 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein DUF4602 PF15375.1 CDI87840.1 - 5.2 7.1 25.1 6 6.9 12.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4602) Menin PF05053.8 CDI87840.1 - 6.8 4.7 14.3 8.2 4.4 9.9 1.2 1 0 0 1 1 1 0 Menin TEX19 PF15553.1 CDI87840.1 - 7 6.4 14.0 7.1 6.4 9.1 1.4 1 1 0 1 1 1 0 Testis-expressed protein 19 RskA PF10099.4 CDI87840.1 - 7 6.3 17.8 11 5.6 12.4 1.3 1 1 0 1 1 1 0 Anti-sigma-K factor rskA SAPS PF04499.10 CDI87840.1 - 8.4 4.8 17.1 13 4.2 11.8 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF4647 PF15504.1 CDI87840.1 - 8.6 5.0 17.6 11 4.7 12.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4647) DUF3138 PF11336.3 CDI87840.1 - 9.7 4.2 16.4 11 4.0 11.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) RskA PF10099.4 CDI87841.1 - 0.0016 18.2 4.8 0.003 17.3 3.3 1.4 1 0 0 1 1 1 1 Anti-sigma-K factor rskA PrpF PF04303.8 CDI87841.1 - 0.018 13.8 1.0 0.024 13.3 0.7 1.1 1 0 0 1 1 1 0 PrpF protein DDRGK PF09756.4 CDI87841.1 - 0.79 9.0 13.9 1.4 8.3 9.6 1.5 1 0 0 1 1 1 0 DDRGK domain DUF4407 PF14362.1 CDI87841.1 - 0.97 8.3 18.6 1.4 7.7 12.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) SID-1_RNA_chan PF13965.1 CDI87841.1 - 1 7.4 5.3 1.3 7.0 3.6 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 RR_TM4-6 PF06459.7 CDI87841.1 - 1.7 8.4 11.2 3.2 7.5 7.7 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF3273 PF11677.3 CDI87842.1 - 5e-14 52.2 0.1 6.6e-14 51.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3273) Chorion_2 PF03964.10 CDI87842.1 - 0.0051 17.3 6.6 0.0084 16.6 4.6 1.3 1 0 0 1 1 1 1 Chorion family 2 CDK2AP PF09806.4 CDI87842.1 - 0.039 14.1 11.5 0.054 13.7 7.9 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein Ribosomal_60s PF00428.14 CDI87842.1 - 0.077 13.4 1.9 0.11 12.9 1.3 1.3 1 0 0 1 1 1 0 60s Acidic ribosomal protein BAF1_ABF1 PF04684.8 CDI87842.1 - 0.14 11.0 13.7 0.17 10.7 9.5 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor RskA PF10099.4 CDI87842.1 - 0.23 11.1 9.2 0.99 9.1 0.0 2.0 1 1 1 2 2 2 0 Anti-sigma-K factor rskA DUF3138 PF11336.3 CDI87842.1 - 0.23 9.6 7.7 0.31 9.1 5.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) DUF2427 PF10348.4 CDI87843.1 - 0.14 11.7 0.3 0.23 11.0 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2427) Apt1 PF10351.4 CDI87844.1 - 0.027 13.3 1.0 0.035 12.9 0.7 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain FKS1_dom1 PF14288.1 CDI87845.1 - 2.6e-19 69.2 3.2 1.4e-18 66.9 2.2 2.2 1 1 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 PID_2 PF14719.1 CDI87845.1 - 0.095 12.3 0.1 0.24 11.0 0.0 1.6 2 0 0 2 2 2 0 Phosphotyrosine interaction domain (PTB/PID) PH_4 PF15404.1 CDI87847.1 - 0.34 10.3 2.1 0.35 10.3 0.0 1.8 2 0 0 2 2 2 0 Pleckstrin homology domain OMP_b-brl PF13505.1 CDI87847.1 - 3.3 7.6 0.0 3.3 7.6 0.0 3.0 3 0 0 3 3 3 0 Outer membrane protein beta-barrel domain DivIC PF04977.10 CDI87848.1 - 0.01 15.2 6.7 0.01 15.2 4.7 2.2 2 0 0 2 2 2 0 Septum formation initiator DUF966 PF06136.8 CDI87848.1 - 0.023 14.1 13.2 0.024 14.0 9.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Med15 PF09606.5 CDI87848.1 - 0.028 12.6 15.7 0.032 12.4 10.9 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Gly-zipper_OmpA PF13436.1 CDI87848.1 - 0.028 14.0 5.3 0.042 13.4 3.7 1.3 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain DUF1510 PF07423.6 CDI87848.1 - 0.039 13.3 23.8 0.054 12.8 16.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) CDC27 PF09507.5 CDI87848.1 - 0.045 12.9 19.8 0.049 12.8 13.7 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Mitofilin PF09731.4 CDI87848.1 - 0.048 12.3 19.2 0.05 12.2 13.3 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein PAT1 PF09770.4 CDI87848.1 - 0.049 11.8 14.7 0.051 11.8 10.2 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Dehydrin PF00257.14 CDI87848.1 - 0.053 13.8 15.4 0.073 13.4 10.7 1.3 1 0 0 1 1 1 0 Dehydrin TMEM51 PF15345.1 CDI87848.1 - 0.058 13.0 12.4 0.067 12.8 8.6 1.1 1 0 0 1 1 1 0 Transmembrane protein 51 Mucin PF01456.12 CDI87848.1 - 0.059 13.1 4.8 0.07 12.8 3.4 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein Apc15p PF05841.6 CDI87848.1 - 0.066 13.9 16.9 0.12 13.1 11.7 1.4 1 0 0 1 1 1 0 Apc15p protein HD-ZIP_N PF04618.7 CDI87848.1 - 0.08 13.4 4.0 0.16 12.5 2.8 1.5 1 0 0 1 1 1 0 HD-ZIP protein N terminus BAF1_ABF1 PF04684.8 CDI87848.1 - 0.092 11.5 9.4 0.11 11.3 6.5 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor SLD3 PF08639.5 CDI87848.1 - 0.12 11.0 12.9 0.13 10.8 8.9 1.1 1 0 0 1 1 1 0 DNA replication regulator SLD3 GHBP PF12772.2 CDI87848.1 - 0.12 11.7 13.4 0.16 11.3 9.3 1.2 1 0 0 1 1 1 0 Growth hormone receptor binding FAM176 PF14851.1 CDI87848.1 - 0.16 11.6 16.4 0.25 10.9 11.4 1.4 1 0 0 1 1 1 0 FAM176 family Hid1 PF12722.2 CDI87848.1 - 0.17 9.5 13.3 0.17 9.5 9.2 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SAPS PF04499.10 CDI87848.1 - 0.25 9.9 14.1 0.3 9.6 9.8 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein PIH1 PF08190.7 CDI87848.1 - 0.29 10.5 15.2 0.35 10.2 10.6 1.1 1 0 0 1 1 1 0 pre-RNA processing PIH1/Nop17 Peptidase_S64 PF08192.6 CDI87848.1 - 0.34 9.1 9.7 0.4 8.9 6.7 1.1 1 0 0 1 1 1 0 Peptidase family S64 Tfb4 PF03850.9 CDI87848.1 - 0.37 10.0 4.5 0.42 9.8 3.1 1.1 1 0 0 1 1 1 0 Transcription factor Tfb4 DUF4647 PF15504.1 CDI87848.1 - 0.38 9.5 15.2 0.45 9.3 10.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4647) GAGA_bind PF06217.7 CDI87848.1 - 0.62 9.9 8.6 0.74 9.7 6.0 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family Neur_chan_memb PF02932.11 CDI87848.1 - 0.87 9.4 7.9 0.98 9.2 5.5 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region ATG22 PF11700.3 CDI87848.1 - 0.94 7.8 2.5 1.1 7.6 1.7 1.2 1 0 0 1 1 1 0 Vacuole effluxer Atg22 like Dicty_REP PF05086.7 CDI87848.1 - 0.99 7.0 12.0 1.2 6.7 8.3 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Nucleoporin2 PF04096.9 CDI87848.1 - 1 9.1 8.3 0.45 10.3 0.2 2.1 2 0 0 2 2 2 0 Nucleoporin autopeptidase Rtf2 PF04641.7 CDI87848.1 - 1.1 8.4 15.4 1.3 8.1 10.7 1.2 1 0 0 1 1 1 0 Rtf2 RING-finger Ycf1 PF05758.7 CDI87848.1 - 1.2 6.7 16.6 1.6 6.3 11.5 1.2 1 0 0 1 1 1 0 Ycf1 DUF4407 PF14362.1 CDI87848.1 - 1.3 7.8 17.5 1.8 7.4 12.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF788 PF05620.6 CDI87848.1 - 1.4 8.7 10.0 0.041 13.7 1.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF788) COX16 PF14138.1 CDI87848.1 - 1.4 9.1 6.9 1 9.5 0.6 2.4 2 0 0 2 2 2 0 Cytochrome c oxidase assembly protein COX16 DUF2201_N PF13203.1 CDI87848.1 - 1.5 7.9 12.9 1.9 7.5 9.0 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain Ndc1_Nup PF09531.5 CDI87848.1 - 1.5 7.1 13.7 1.9 6.8 9.5 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF4551 PF15087.1 CDI87848.1 - 1.5 7.0 10.9 1.8 6.8 7.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) FLO_LFY PF01698.11 CDI87848.1 - 1.9 7.2 11.7 2.4 6.8 8.1 1.2 1 0 0 1 1 1 0 Floricaula / Leafy protein Pap_E4 PF02711.9 CDI87848.1 - 1.9 9.3 15.2 1.3 9.9 8.1 2.0 1 1 1 2 2 2 0 E4 protein Pex16 PF08610.5 CDI87848.1 - 2.1 7.2 9.0 2.8 6.8 6.2 1.2 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) XAP5 PF04921.9 CDI87848.1 - 2.2 7.7 18.7 2.9 7.4 13.0 1.1 1 0 0 1 1 1 0 XAP5, circadian clock regulator TATR PF03430.8 CDI87848.1 - 2.3 6.7 8.6 2.3 6.7 6.0 1.0 1 0 0 1 1 1 0 Trans-activating transcriptional regulator PAXIP1_C PF15364.1 CDI87848.1 - 2.5 8.0 20.8 0.33 10.8 4.4 2.3 2 0 0 2 2 2 0 PAXIP1-associated-protein-1 C term PTIP binding protein Nucleo_P87 PF07267.6 CDI87848.1 - 2.8 6.5 10.6 3.1 6.3 7.3 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 FAM60A PF15396.1 CDI87848.1 - 2.8 7.6 11.7 4 7.1 8.1 1.3 1 0 0 1 1 1 0 Protein Family FAM60A CENP-T PF15511.1 CDI87848.1 - 5.3 6.1 21.5 6.2 5.9 14.9 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Mem_trans PF03547.13 CDI87848.1 - 6.3 4.9 8.6 7.1 4.8 6.0 1.1 1 0 0 1 1 1 0 Membrane transport protein eIF-3c_N PF05470.7 CDI87848.1 - 7.9 4.4 18.3 10 4.0 12.7 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus SpoIIIAH PF12685.2 CDI87848.1 - 8.9 5.7 26.2 12 5.3 18.2 1.1 1 0 0 1 1 1 0 SpoIIIAH-like protein Abhydrolase_9_N PF15420.1 CDI87850.1 - 0.0031 17.2 1.7 0.0031 17.2 1.2 1.4 2 0 0 2 2 2 1 Alpha/beta-hydrolase family N-terminus UPF0564 PF10595.4 CDI87850.1 - 0.025 13.4 37.9 0.039 12.8 26.3 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0564 DUF4401 PF14351.1 CDI87850.1 - 0.03 13.3 3.3 0.04 12.8 2.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4401) DUF912 PF06024.7 CDI87850.1 - 0.2 11.7 0.2 0.2 11.7 0.1 3.2 2 1 1 3 3 3 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF3357 PF11837.3 CDI87850.1 - 0.76 9.6 13.2 0.96 9.3 0.6 3.4 1 1 3 4 4 4 0 Domain of unknown function (DUF3357) DUF3899 PF13038.1 CDI87850.1 - 0.8 9.8 0.1 0.8 9.8 0.0 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF3899) SID-1_RNA_chan PF13965.1 CDI87850.1 - 1.2 7.1 14.0 1.9 6.5 9.7 1.3 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DUF572 PF04502.8 CDI87851.1 - 0.0036 16.5 11.8 0.0036 16.5 8.2 3.0 2 1 1 3 3 3 1 Family of unknown function (DUF572) Dehydrin PF00257.14 CDI87851.1 - 0.23 11.7 47.7 0.13 12.5 10.4 3.6 3 0 0 3 3 3 0 Dehydrin zf-DHHC PF01529.15 CDI87851.1 - 2.2 7.6 13.1 0.32 10.3 0.5 3.2 3 0 0 3 3 3 0 DHHC palmitoyltransferase Herpes_UL87 PF03043.9 CDI87851.1 - 3 6.1 17.9 0.066 11.5 3.6 2.2 1 1 1 2 2 2 0 Herpesvirus UL87 family Peptidase_S49_N PF08496.5 CDI87851.1 - 4 7.2 29.1 0.7 9.6 2.2 3.4 3 0 0 3 3 3 0 Peptidase family S49 N-terminal Sporozoite_P67 PF05642.6 CDI87851.1 - 5.7 4.6 43.8 3.1 5.5 9.0 2.3 2 0 0 2 2 2 0 Sporozoite P67 surface antigen Utp14 PF04615.8 CDI87851.1 - 6.6 4.7 58.7 1.2 7.2 10.7 2.3 2 0 0 2 2 2 0 Utp14 protein PPP4R2 PF09184.6 CDI87852.1 - 0.36 10.3 9.6 0.72 9.3 6.7 1.4 1 0 0 1 1 1 0 PPP4R2 Neur_chan_memb PF02932.11 CDI87853.1 - 0.38 10.5 11.1 0.031 14.1 1.1 2.6 2 1 1 3 3 3 0 Neurotransmitter-gated ion-channel transmembrane region zf-DHHC PF01529.15 CDI87853.1 - 0.62 9.4 2.0 13 5.0 0.2 2.3 2 0 0 2 2 2 0 DHHC palmitoyltransferase Med15 PF09606.5 CDI87856.1 - 0.0056 14.9 37.0 0.0075 14.5 25.6 1.2 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal TMEM247 PF15444.1 CDI87856.1 - 0.024 14.4 5.9 0.038 13.8 4.1 1.3 1 0 0 1 1 1 0 Transmembrane protein 247 AAA_23 PF13476.1 CDI87856.1 - 0.035 14.4 5.3 0.046 14.0 3.6 1.2 1 0 0 1 1 1 0 AAA domain Suc_Fer-like PF06999.7 CDI87856.1 - 0.11 12.4 2.9 0.16 11.9 2.0 1.2 1 0 0 1 1 1 0 Sucrase/ferredoxin-like Activator_LAG-3 PF11498.3 CDI87856.1 - 0.14 10.8 36.3 0.19 10.4 25.2 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 DUF1690 PF07956.6 CDI87856.1 - 0.57 10.1 13.0 0.81 9.6 9.0 1.2 1 0 0 1 1 1 0 Protein of Unknown function (DUF1690) HlyD_2 PF12700.2 CDI87856.1 - 0.72 8.9 5.7 0.8 8.8 4.0 1.2 1 0 0 1 1 1 0 HlyD family secretion protein zf-ZPR1 PF03367.8 CDI87856.1 - 0.73 8.9 7.0 1.5 7.9 4.8 1.6 1 1 0 1 1 1 0 ZPR1 zinc-finger domain FliP PF00813.15 CDI87856.1 - 1.3 8.7 4.2 1.7 8.2 2.9 1.2 1 0 0 1 1 1 0 FliP family Peptidase_M3 PF01432.15 CDI87856.1 - 1.5 7.8 10.9 2 7.3 7.5 1.1 1 0 0 1 1 1 0 Peptidase family M3 HI0933_like PF03486.9 CDI87856.1 - 1.6 7.1 9.0 2.2 6.6 6.3 1.2 1 0 0 1 1 1 0 HI0933-like protein Paramyxo_ncap PF00973.14 CDI87856.1 - 2.5 6.7 9.6 3 6.4 6.7 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein PAT1 PF09770.4 CDI87856.1 - 2.7 6.1 33.7 3.3 5.8 23.4 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF3103 PF11301.3 CDI87856.1 - 3.3 6.2 13.2 4.9 5.7 9.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3103) TFIIA PF03153.8 CDI87856.1 - 3.6 7.3 32.7 5.1 6.8 22.6 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit LUC7 PF03194.10 CDI87857.1 - 1.9e-07 30.9 0.3 1.9e-07 30.9 0.2 3.4 1 1 1 2 2 2 1 LUC7 N_terminus BUD22 PF09073.5 CDI87858.1 - 0.0025 16.9 14.6 0.0025 16.9 10.2 2.3 2 0 0 2 2 2 1 BUD22 HTH_32 PF13565.1 CDI87858.1 - 0.037 14.8 3.0 0.2 12.4 0.0 2.9 2 0 0 2 2 2 0 Homeodomain-like domain Plasmodium_Vir PF05795.6 CDI87858.1 - 0.25 10.4 10.1 0.025 13.7 2.6 2.0 2 0 0 2 2 2 0 Plasmodium vivax Vir protein DUF3893 PF13032.1 CDI87859.1 - 0.13 12.3 0.0 0.22 11.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3893) Raftlin PF15250.1 CDI87860.1 - 4.7 5.6 19.7 5.9 5.2 13.6 1.1 1 0 0 1 1 1 0 Raftlin TFIIA PF03153.8 CDI87860.1 - 5.3 6.8 23.3 5.7 6.7 16.1 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Fibrinogen_C PF00147.13 CDI87861.1 - 0.023 14.2 0.0 0.041 13.4 0.0 1.3 1 0 0 1 1 1 0 Fibrinogen beta and gamma chains, C-terminal globular domain Ribosomal_60s PF00428.14 CDI87861.1 - 4.4 7.7 14.8 0.53 10.7 7.0 1.9 2 0 0 2 2 2 0 60s Acidic ribosomal protein PAT1 PF09770.4 CDI87862.1 - 0.0028 15.9 27.6 0.0027 16.0 19.1 1.1 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 DUF2072 PF09845.4 CDI87862.1 - 0.0034 17.3 6.6 0.0048 16.8 4.6 1.3 1 0 0 1 1 1 1 Zn-ribbon containing protein (DUF2072) Suf PF05843.9 CDI87862.1 - 0.0067 16.1 13.3 0.0079 15.9 9.2 1.2 1 0 0 1 1 1 1 Suppressor of forked protein (Suf) TfuA PF07812.7 CDI87862.1 - 0.0079 15.6 1.1 0.0096 15.3 0.4 1.3 1 1 0 1 1 1 1 TfuA-like protein Med15 PF09606.5 CDI87862.1 - 0.016 13.4 50.2 0.023 12.9 34.8 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal RR_TM4-6 PF06459.7 CDI87862.1 - 0.027 14.3 11.7 0.032 14.1 8.1 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DDHD PF02862.12 CDI87862.1 - 0.038 13.7 8.6 0.038 13.7 5.9 1.1 1 0 0 1 1 1 0 DDHD domain HemX PF04375.9 CDI87862.1 - 0.046 12.3 31.0 0.059 11.9 21.5 1.0 1 0 0 1 1 1 0 HemX FLO_LFY PF01698.11 CDI87862.1 - 0.061 12.1 9.7 0.066 12.0 6.7 1.2 1 0 0 1 1 1 0 Floricaula / Leafy protein SpoVR PF04293.8 CDI87862.1 - 0.067 11.5 13.6 0.083 11.2 9.5 1.0 1 0 0 1 1 1 0 SpoVR like protein DUF2868 PF11067.3 CDI87862.1 - 0.072 12.2 12.7 0.095 11.8 8.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2868) SAGA-Tad1 PF12767.2 CDI87862.1 - 0.073 12.7 13.5 0.087 12.4 9.3 1.1 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit AUX_IAA PF02309.11 CDI87862.1 - 0.095 12.4 7.3 0.099 12.3 5.1 1.2 1 0 0 1 1 1 0 AUX/IAA family DUF2235 PF09994.4 CDI87862.1 - 0.15 11.3 5.6 0.18 11.1 3.9 1.0 1 0 0 1 1 1 0 Uncharacterized alpha/beta hydrolase domain (DUF2235) DUF2422 PF10337.4 CDI87862.1 - 0.19 10.4 5.6 0.24 10.1 3.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2422) FimP PF09766.4 CDI87862.1 - 0.2 10.7 25.5 0.25 10.3 17.6 1.1 1 0 0 1 1 1 0 Fms-interacting protein Neur_chan_memb PF02932.11 CDI87862.1 - 0.22 11.3 3.7 0.22 11.4 2.6 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Baculo_PP31 PF05311.6 CDI87862.1 - 0.25 10.5 15.5 0.32 10.2 10.7 1.1 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) DUF4557 PF15101.1 CDI87862.1 - 0.25 11.1 22.1 0.37 10.6 15.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) Peroxin-13_N PF04088.8 CDI87862.1 - 0.28 11.1 5.6 0.43 10.5 3.9 1.3 1 0 0 1 1 1 0 Peroxin 13, N-terminal region HGTP_anticodon2 PF12745.2 CDI87862.1 - 0.29 10.2 12.7 0.37 9.8 8.8 1.1 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs eIF-3_zeta PF05091.7 CDI87862.1 - 0.32 9.5 19.2 0.39 9.2 13.3 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF3260 PF11658.3 CDI87862.1 - 0.38 8.8 9.0 0.36 8.9 6.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3260) HD-ZIP_N PF04618.7 CDI87862.1 - 0.46 11.0 4.9 0.65 10.5 3.4 1.3 1 0 0 1 1 1 0 HD-ZIP protein N terminus FAM60A PF15396.1 CDI87862.1 - 0.46 10.1 9.0 0.57 9.9 6.2 1.1 1 0 0 1 1 1 0 Protein Family FAM60A G-alpha PF00503.15 CDI87862.1 - 0.48 9.0 16.0 0.59 8.7 11.1 1.1 1 0 0 1 1 1 0 G-protein alpha subunit Peptidase_S49_N PF08496.5 CDI87862.1 - 0.5 10.1 13.7 0.73 9.6 9.5 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DHHW PF14286.1 CDI87862.1 - 0.54 9.5 9.4 0.72 9.1 6.5 1.2 1 0 0 1 1 1 0 DHHW protein MMR1 PF08505.5 CDI87862.1 - 0.63 10.0 14.7 0.68 9.9 10.2 1.2 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein GOLD_2 PF13897.1 CDI87862.1 - 0.69 10.1 6.1 0.97 9.6 4.2 1.2 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking Peptidase_S15 PF02129.13 CDI87862.1 - 0.76 9.1 14.7 1 8.6 10.2 1.2 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) NARP1 PF12569.3 CDI87862.1 - 0.97 8.1 17.9 1.4 7.6 12.4 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Dala_Dala_lig_N PF01820.16 CDI87862.1 - 1.1 9.6 7.1 1.7 8.9 4.9 1.4 1 0 0 1 1 1 0 D-ala D-ala ligase N-terminus Presenilin PF01080.12 CDI87862.1 - 1.2 7.9 5.6 1.2 7.8 3.9 1.1 1 0 0 1 1 1 0 Presenilin Pex14_N PF04695.8 CDI87862.1 - 1.7 8.7 25.6 0.1 12.6 12.9 2.0 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Serinc PF03348.10 CDI87862.1 - 2 7.0 14.2 2.4 6.7 9.8 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) PBP1_TM PF14812.1 CDI87862.1 - 2.1 8.7 9.2 2.9 8.2 6.4 1.1 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Gti1_Pac2 PF09729.4 CDI87862.1 - 2.6 7.8 13.4 3.4 7.5 9.3 1.2 1 0 0 1 1 1 0 Gti1/Pac2 family LIM_bind PF01803.11 CDI87862.1 - 2.8 7.0 18.9 3.8 6.5 13.1 1.1 1 0 0 1 1 1 0 LIM-domain binding protein HCO3_cotransp PF00955.16 CDI87862.1 - 3.7 6.0 4.8 4.7 5.7 3.3 1.1 1 0 0 1 1 1 0 HCO3- transporter family AAA_23 PF13476.1 CDI87862.1 - 4.1 7.6 21.7 5 7.3 15.0 1.1 1 0 0 1 1 1 0 AAA domain OATP PF03137.15 CDI87862.1 - 4.8 5.1 12.5 5.9 4.8 8.7 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family FAM176 PF14851.1 CDI87862.1 - 5.5 6.6 7.1 8.1 6.1 4.9 1.2 1 0 0 1 1 1 0 FAM176 family DUF4220 PF13968.1 CDI87862.1 - 5.5 5.9 7.9 6.9 5.6 5.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4220) DUF2058 PF09831.4 CDI87862.1 - 6.4 6.6 28.8 10 5.9 19.9 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2058) DUF4638 PF15472.1 CDI87862.1 - 6.9 6.1 12.1 7.8 5.9 8.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) Band_3_cyto PF07565.8 CDI87862.1 - 7 6.0 16.7 8.8 5.7 11.6 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain DDRGK PF09756.4 CDI87862.1 - 7 6.0 22.9 9 5.6 15.9 1.2 1 0 0 1 1 1 0 DDRGK domain FemAB PF02388.11 CDI87862.1 - 7.9 5.0 19.4 10 4.7 13.5 1.1 1 0 0 1 1 1 0 FemAB family Spore_coat_CotO PF14153.1 CDI87862.1 - 8 5.8 24.7 11 5.4 17.1 1.1 1 0 0 1 1 1 0 Spore coat protein CotO DUF2215 PF10225.4 CDI87862.1 - 8.1 5.8 7.3 11 5.4 5.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) AIF_C PF14721.1 CDI87862.1 - 8.4 6.6 15.6 2.9 8.1 8.6 1.7 2 0 0 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Kei1 PF08552.6 CDI87862.1 - 9 5.9 17.4 3.4 7.2 8.4 2.0 2 0 0 2 2 2 0 Inositolphosphorylceramide synthase subunit Kei1 Hom_end_hint PF05203.11 CDI87862.1 - 9.1 5.9 10.4 13 5.4 7.2 1.2 1 0 0 1 1 1 0 Hom_end-associated Hint Neur_chan_memb PF02932.11 CDI87863.1 - 5.9 6.6 19.1 9.1 6.0 13.3 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF3273 PF11677.3 CDI87864.1 - 7.6e-57 192.5 11.0 8.6e-57 192.3 7.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3273) DUF2568 PF10823.3 CDI87864.1 - 0.00083 19.5 0.3 0.0022 18.1 0.2 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2568) Activator_LAG-3 PF11498.3 CDI87865.1 - 0.0061 15.3 14.1 0.0061 15.3 9.8 2.5 2 0 0 2 2 2 2 Transcriptional activator LAG-3 Suf PF05843.9 CDI87865.1 - 1.3 8.7 12.3 0.053 13.2 3.9 2.0 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) Mucin PF01456.12 CDI87866.1 - 0.0016 18.2 4.4 0.0021 17.8 3.0 1.3 1 0 0 1 1 1 1 Mucin-like glycoprotein DUF3984 PF13136.1 CDI87866.1 - 0.017 14.4 15.8 0.021 14.0 10.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3984) DUF2217 PF10265.4 CDI87866.1 - 0.027 13.2 16.0 0.029 13.1 11.1 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) DUF1510 PF07423.6 CDI87866.1 - 0.029 13.7 18.0 0.033 13.5 12.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) FAM176 PF14851.1 CDI87866.1 - 0.031 13.9 10.8 0.037 13.7 7.5 1.1 1 0 0 1 1 1 0 FAM176 family TAF4 PF05236.9 CDI87866.1 - 0.054 12.7 24.8 0.064 12.5 17.2 1.0 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family TMEM51 PF15345.1 CDI87866.1 - 0.061 13.0 20.6 0.07 12.8 14.3 1.1 1 0 0 1 1 1 0 Transmembrane protein 51 DDRGK PF09756.4 CDI87866.1 - 0.12 11.7 20.2 0.17 11.3 14.0 1.3 1 0 0 1 1 1 0 DDRGK domain CDK2AP PF09806.4 CDI87866.1 - 0.21 11.8 33.9 0.27 11.4 23.5 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein HSD3 PF15244.1 CDI87866.1 - 0.31 10.2 15.2 0.35 10.0 10.5 1.0 1 0 0 1 1 1 0 Hydroxy-steroid dehydrogenase GHMP_kinases_N PF00288.21 CDI87866.1 - 0.36 10.9 0.2 0.36 10.9 0.1 2.1 2 0 0 2 2 2 0 GHMP kinases N terminal domain Plasmodium_Vir PF05795.6 CDI87866.1 - 0.38 9.9 8.5 0.46 9.6 5.9 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Apc15p PF05841.6 CDI87866.1 - 0.44 11.2 24.6 0.59 10.8 17.1 1.2 1 0 0 1 1 1 0 Apc15p protein DUF572 PF04502.8 CDI87866.1 - 0.51 9.5 22.6 0.59 9.3 15.7 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF966 PF06136.8 CDI87866.1 - 0.54 9.6 23.8 0.62 9.4 16.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF966) RNase_H2-Ydr279 PF09468.5 CDI87866.1 - 0.54 9.4 8.4 0.63 9.1 5.8 1.1 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) Ycf1 PF05758.7 CDI87866.1 - 0.55 7.8 18.0 0.61 7.7 12.5 1.0 1 0 0 1 1 1 0 Ycf1 Na_trans_assoc PF06512.8 CDI87866.1 - 0.67 9.8 10.2 0.98 9.3 7.1 1.3 1 0 0 1 1 1 0 Sodium ion transport-associated RAP1 PF07218.6 CDI87866.1 - 0.84 7.6 5.0 0.82 7.6 3.5 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DUF2052 PF09747.4 CDI87866.1 - 0.99 9.2 21.8 1.4 8.7 15.1 1.2 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) PLRV_ORF5 PF01690.12 CDI87866.1 - 1.2 8.1 20.3 1.4 7.9 14.0 1.0 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein FAM60A PF15396.1 CDI87866.1 - 1.4 8.6 22.6 1.7 8.3 15.7 1.0 1 0 0 1 1 1 0 Protein Family FAM60A Apt1 PF10351.4 CDI87866.1 - 1.6 7.4 19.2 1.8 7.3 13.3 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain P5-ATPase PF12409.3 CDI87866.1 - 1.7 8.5 8.9 2.4 8.0 6.2 1.3 1 0 0 1 1 1 0 P5-type ATPase cation transporter GPCR_chapero_1 PF11904.3 CDI87866.1 - 1.8 7.6 17.9 2.2 7.3 12.4 1.1 1 0 0 1 1 1 0 GPCR-chaperone DUF4045 PF13254.1 CDI87866.1 - 2 7.5 21.8 2.4 7.3 15.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Hid1 PF12722.2 CDI87866.1 - 2.5 5.6 26.7 2.8 5.5 18.5 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF822 PF05687.8 CDI87866.1 - 2.8 8.2 17.2 4 7.7 11.9 1.3 1 0 0 1 1 1 0 Plant protein of unknown function (DUF822) Vfa1 PF08432.5 CDI87866.1 - 2.9 7.8 22.5 3.8 7.5 15.6 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Pex16 PF08610.5 CDI87866.1 - 3.1 6.6 18.8 3.5 6.5 13.1 1.1 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) SpoIIIAH PF12685.2 CDI87866.1 - 3.5 7.0 25.5 4.1 6.8 17.7 1.1 1 0 0 1 1 1 0 SpoIIIAH-like protein Peptidase_S64 PF08192.6 CDI87866.1 - 3.7 5.7 19.6 4.2 5.5 13.6 1.0 1 0 0 1 1 1 0 Peptidase family S64 Parvo_coat PF00740.13 CDI87866.1 - 3.7 6.3 22.4 4.4 6.1 15.5 1.0 1 0 0 1 1 1 0 Parvovirus coat protein VP2 Spc7_N PF15402.1 CDI87866.1 - 4.3 5.2 26.3 5.3 4.9 18.2 1.1 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 FAM163 PF15069.1 CDI87866.1 - 4.8 7.7 9.9 6.4 7.3 6.9 1.2 1 0 0 1 1 1 0 FAM163 family DUF2146 PF10220.4 CDI87866.1 - 5.4 4.8 21.8 6.2 4.6 15.1 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2146) Mem_trans PF03547.13 CDI87866.1 - 5.4 5.1 11.9 5.6 5.1 8.2 1.0 1 0 0 1 1 1 0 Membrane transport protein CDC45 PF02724.9 CDI87866.1 - 5.7 4.8 23.3 7.2 4.5 16.1 1.0 1 0 0 1 1 1 0 CDC45-like protein SAPS PF04499.10 CDI87866.1 - 5.8 5.4 19.3 6.5 5.2 13.4 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein TFIIA PF03153.8 CDI87866.1 - 5.8 6.6 44.5 7 6.4 30.9 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF3807 PF12720.2 CDI87866.1 - 6 6.9 27.9 7.8 6.6 19.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) DUF4551 PF15087.1 CDI87866.1 - 6.3 5.0 19.0 7.1 4.8 13.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) SPX PF03105.14 CDI87866.1 - 6.3 6.4 23.0 7.4 6.2 15.9 1.1 1 0 0 1 1 1 0 SPX domain Rtf2 PF04641.7 CDI87866.1 - 6.8 5.8 23.1 10 5.2 16.0 1.3 1 0 0 1 1 1 0 Rtf2 RING-finger eIF-3_zeta PF05091.7 CDI87866.1 - 8 4.9 24.0 11 4.4 16.6 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Raftlin PF15250.1 CDI87866.1 - 8.2 4.8 18.4 9.8 4.5 12.8 1.1 1 0 0 1 1 1 0 Raftlin Cyto_heme_lyase PF01265.12 CDI87866.1 - 9.4 5.7 22.6 10 5.5 15.7 1.1 1 0 0 1 1 1 0 Cytochrome c/c1 heme lyase Membralin PF09746.4 CDI87866.1 - 9.4 5.1 10.9 11 4.9 7.6 1.1 1 0 0 1 1 1 0 Tumour-associated protein CMV_US PF08001.6 CDI87866.1 - 9.5 5.1 11.5 10 5.1 0.3 2.1 1 1 0 2 2 2 0 CMV US Utp14 PF04615.8 CDI87866.1 - 9.6 4.2 28.8 11 4.0 19.9 1.0 1 0 0 1 1 1 0 Utp14 protein Neur_chan_memb PF02932.11 CDI87866.1 - 10 5.9 17.4 12 5.7 12.1 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region NESP55 PF06390.7 CDI87867.1 - 1.4 8.2 17.3 1.9 7.8 12.0 1.2 1 0 0 1 1 1 0 Neuroendocrine-specific golgi protein P55 (NESP55) Trypan_PARP PF05887.6 CDI87867.1 - 3.1 7.6 16.8 3.6 7.3 11.7 1.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) PAT1 PF09770.4 CDI87870.1 - 0.6 8.2 66.7 0.67 8.1 46.2 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Borrelia_P83 PF05262.6 CDI87871.1 - 0.001 17.4 0.6 0.001 17.4 0.4 1.2 1 0 0 1 1 1 1 Borrelia P83/100 protein AAA_23 PF13476.1 CDI87871.1 - 0.0025 18.1 0.3 0.003 17.9 0.2 1.2 1 0 0 1 1 1 1 AAA domain Med15 PF09606.5 CDI87871.1 - 0.0065 14.7 30.9 0.0095 14.1 21.4 1.3 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal DUF605 PF04652.11 CDI87871.1 - 0.037 13.4 21.1 0.044 13.1 14.7 1.1 1 0 0 1 1 1 0 Vta1 like PAT1 PF09770.4 CDI87871.1 - 0.48 8.5 23.2 0.58 8.3 16.1 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 CAF-1_p150 PF11600.3 CDI87871.1 - 0.88 8.9 26.4 0.041 13.2 10.3 2.2 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal zf-H2C2_5 PF13909.1 CDI87873.1 - 3.3 8.1 5.6 3.1 8.2 0.8 2.6 2 0 0 2 2 2 0 C2H2-type zinc-finger domain Troponin PF00992.15 CDI87875.1 - 0.054 13.5 0.1 0.1 12.6 0.0 1.4 1 1 0 1 1 1 0 Troponin Ribosomal_60s PF00428.14 CDI87877.1 - 4.5 7.7 30.9 4.5 7.7 11.3 2.6 2 0 0 2 2 2 0 60s Acidic ribosomal protein DUF2753 PF10952.3 CDI87878.1 - 0.11 12.4 1.8 0.16 11.9 1.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2753) Ribosomal_S18 PF01084.15 CDI87878.1 - 0.67 9.8 2.5 0.61 9.9 0.2 2.0 2 0 0 2 2 2 0 Ribosomal protein S18 DUF4603 PF15376.1 CDI87879.1 - 0.16 9.1 11.3 0.18 8.9 7.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) DcuC PF03606.10 CDI87879.1 - 0.65 8.1 4.5 0.75 7.9 3.1 1.1 1 0 0 1 1 1 0 C4-dicarboxylate anaerobic carrier SelP_N PF04592.9 CDI87879.1 - 1.1 8.6 25.4 1.1 8.5 17.6 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Zip PF02535.17 CDI87879.1 - 1.2 8.0 19.1 1.2 8.0 13.2 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter DUF2217 PF10265.4 CDI87879.1 - 1.7 7.3 9.6 1.9 7.1 6.7 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) MARCKS PF02063.12 CDI87879.1 - 2.3 7.9 28.8 2.6 7.8 20.0 1.0 1 0 0 1 1 1 0 MARCKS family Bud13 PF09736.4 CDI87879.1 - 4 7.6 19.1 4.3 7.5 13.3 1.3 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex DUF3984 PF13136.1 CDI87879.1 - 5.8 6.0 19.4 5.7 6.0 13.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3984) Peptidase_S49_N PF08496.5 CDI87879.1 - 6 6.6 15.9 7.1 6.4 11.0 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Spore_coat_CotO PF14153.1 CDI87879.1 - 6.1 6.2 24.6 7.1 6.0 17.0 1.3 1 0 0 1 1 1 0 Spore coat protein CotO Serinc PF03348.10 CDI87879.1 - 6.9 5.2 14.7 6.8 5.2 10.2 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) Hid1 PF12722.2 CDI87879.1 - 7.6 4.0 16.3 7.2 4.1 11.3 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein CDK5_activator PF03261.10 CDI87879.1 - 7.6 5.7 18.4 7.8 5.7 12.7 1.0 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein DUF2215 PF10225.4 CDI87879.1 - 7.8 5.8 7.5 8.3 5.7 5.2 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) Peptidase_U57 PF05582.7 CDI87879.1 - 8.2 5.3 14.3 8.5 5.2 9.9 1.1 1 0 0 1 1 1 0 YabG peptidase U57 DUF4446 PF14584.1 CDI87879.1 - 8.6 6.1 8.9 10 5.9 6.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) Helicase_RecD PF05127.9 CDI87879.1 - 9.4 5.8 16.4 11 5.5 11.4 1.1 1 0 0 1 1 1 0 Helicase GRIM-19 PF06212.7 CDI87881.1 - 0.032 13.9 1.6 0.052 13.2 1.1 1.3 1 0 0 1 1 1 0 GRIM-19 protein DUF3446 PF11928.3 CDI87881.1 - 1.2 9.3 13.9 0.72 10.0 3.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3446) DUF4407 PF14362.1 CDI87881.1 - 1.9 7.3 16.3 2.2 7.1 11.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Atg14 PF10186.4 CDI87881.1 - 9.2 5.1 17.6 11 4.8 12.2 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 BAF1_ABF1 PF04684.8 CDI87882.1 - 0.069 12.0 8.4 0.081 11.7 5.8 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor TFIIA PF03153.8 CDI87882.1 - 0.41 10.4 22.2 0.49 10.2 15.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Med15 PF09606.5 CDI87882.1 - 0.44 8.6 23.8 0.49 8.5 16.5 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Mitofilin PF09731.4 CDI87882.1 - 3.7 6.0 18.4 4.2 5.9 12.8 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Utp14 PF04615.8 CDI87882.1 - 4.7 5.2 21.1 5.6 4.9 14.6 1.0 1 0 0 1 1 1 0 Utp14 protein CAF-1_p150 PF11600.3 CDI87883.1 - 0.17 11.2 34.5 0.2 11.0 23.9 1.0 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal SprA-related PF12118.3 CDI87883.1 - 0.43 9.8 58.4 0.5 9.6 40.5 1.0 1 0 0 1 1 1 0 SprA-related family SR-25 PF10500.4 CDI87883.1 - 2.7 7.4 37.4 0.089 12.2 16.3 2.0 1 1 1 2 2 2 0 Nuclear RNA-splicing-associated protein SSP160 PF06933.6 CDI87883.1 - 2.8 5.8 8.3 3.2 5.6 5.7 1.0 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 HemX PF04375.9 CDI87883.1 - 4.9 5.6 39.9 6.3 5.2 27.6 1.1 1 0 0 1 1 1 0 HemX Macoilin PF09726.4 CDI87884.1 - 0.98 7.6 27.2 1.1 7.4 18.9 1.0 1 0 0 1 1 1 0 Transmembrane protein Mcm10 PF09332.6 CDI87884.1 - 2.7 7.2 8.6 3.8 6.7 6.0 1.3 1 0 0 1 1 1 0 Mcm10 replication factor Peptidase_S64 PF08192.6 CDI87884.1 - 6.6 4.9 23.2 7.5 4.7 16.0 1.0 1 0 0 1 1 1 0 Peptidase family S64 Activator_LAG-3 PF11498.3 CDI87886.1 - 0.00043 19.1 80.8 0.0061 15.3 28.7 3.2 3 0 0 3 3 3 3 Transcriptional activator LAG-3 DUF98 PF01947.11 CDI87886.1 - 0.18 11.5 5.6 0.43 10.3 3.3 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF98) TPR_11 PF13414.1 CDI87887.1 - 2e-20 72.2 18.3 2.8e-10 39.6 1.4 2.4 1 1 2 3 3 3 3 TPR repeat TPR_16 PF13432.1 CDI87887.1 - 1.7e-08 34.8 4.2 1.1e-06 29.1 1.3 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.12 CDI87887.1 - 1.6e-07 30.6 11.0 0.00014 21.5 0.2 3.8 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_17 PF13431.1 CDI87887.1 - 3.6e-06 26.7 1.5 0.12 12.6 0.0 3.6 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 CDI87887.1 - 1.1e-05 24.7 9.8 0.0058 16.2 0.3 3.6 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 CDI87887.1 - 3.8e-05 23.9 2.5 0.00074 19.9 0.0 2.9 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 CDI87887.1 - 5.1e-05 23.5 2.8 0.00096 19.4 0.8 2.5 1 1 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 CDI87887.1 - 5.3e-05 22.7 2.7 0.089 12.6 0.4 3.4 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 CDI87887.1 - 0.0018 18.1 8.0 0.029 14.3 0.3 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.1 CDI87887.1 - 0.015 15.1 2.0 0.048 13.5 0.9 2.1 1 1 1 2 2 2 0 Tetratricopeptide repeat MIT PF04212.13 CDI87887.1 - 0.021 14.7 4.7 0.38 10.6 0.4 2.5 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain TPR_20 PF14561.1 CDI87887.1 - 0.022 14.8 0.9 0.071 13.2 0.6 2.0 1 1 0 1 1 1 0 Tetratricopeptide repeat Apc3 PF12895.2 CDI87887.1 - 0.023 14.8 4.2 0.059 13.5 1.0 2.6 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 NDUFB10 PF10249.4 CDI87887.1 - 0.05 13.7 0.6 0.097 12.8 0.1 1.7 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase subunit 10 TPR_6 PF13174.1 CDI87887.1 - 0.2 12.1 3.2 2.8 8.5 0.0 3.4 3 2 1 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.1 CDI87887.1 - 0.21 11.5 1.2 2.4 8.2 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF2508 PF10704.4 CDI87887.1 - 0.7 10.1 4.3 3.4 7.8 0.6 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF2508) DUF1510 PF07423.6 CDI87889.1 - 1.3 8.3 31.5 1.9 7.7 21.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Herpes_DNAp_acc PF04929.7 CDI87889.1 - 2.7 6.8 27.4 3.1 6.6 19.0 1.0 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Mem_trans PF03547.13 CDI87889.1 - 7.6 4.7 20.5 12 4.1 14.2 1.3 1 0 0 1 1 1 0 Membrane transport protein SR-25 PF10500.4 CDI87890.1 - 1.3e-07 31.3 28.4 4.7e-05 22.9 8.9 2.1 2 0 0 2 2 2 2 Nuclear RNA-splicing-associated protein NARP1 PF12569.3 CDI87890.1 - 0.0053 15.5 9.9 0.0092 14.7 6.9 1.3 1 0 0 1 1 1 1 NMDA receptor-regulated protein 1 RR_TM4-6 PF06459.7 CDI87890.1 - 0.025 14.4 5.6 0.028 14.3 3.8 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Peptidase_S49_N PF08496.5 CDI87890.1 - 0.035 13.8 7.8 0.016 15.0 3.3 1.8 2 0 0 2 2 2 0 Peptidase family S49 N-terminal eIF-3_zeta PF05091.7 CDI87890.1 - 0.044 12.4 13.0 0.067 11.8 9.0 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF2448 PF10476.4 CDI87890.1 - 0.23 10.9 4.9 0.12 11.9 0.9 2.2 2 0 0 2 2 2 0 Protein of unknown function C-terminus (DUF2448) Het-C PF07217.6 CDI87890.1 - 0.43 8.6 10.9 0.72 7.9 7.6 1.3 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C Raftlin PF15250.1 CDI87890.1 - 0.47 8.9 15.5 0.22 10.0 8.1 1.9 2 0 0 2 2 2 0 Raftlin CAF-1_p150 PF11600.3 CDI87890.1 - 0.56 9.5 31.2 0.11 11.9 13.4 2.1 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Herpes_LMP2 PF07415.6 CDI87890.1 - 0.81 8.2 4.9 1.4 7.3 3.4 1.3 1 0 0 1 1 1 0 Gammaherpesvirus latent membrane protein (LMP2) protein DUF4175 PF13779.1 CDI87890.1 - 1.2 6.7 30.3 2 5.9 21.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) CDC45 PF02724.9 CDI87890.1 - 1.2 7.0 22.7 1.3 6.9 14.4 1.7 1 1 1 2 2 2 0 CDC45-like protein DDHD PF02862.12 CDI87890.1 - 1.5 8.5 19.5 0.82 9.4 9.7 2.0 2 0 0 2 2 2 0 DDHD domain DUF4407 PF14362.1 CDI87890.1 - 1.9 7.3 11.1 2.5 6.9 7.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) RNA_pol_Rpb1_5 PF04998.12 CDI87890.1 - 2 7.5 9.7 0.91 8.7 4.8 1.6 2 0 0 2 2 2 0 RNA polymerase Rpb1, domain 5 BaxI_1 PF12811.2 CDI87890.1 - 2.2 7.3 4.2 3.9 6.5 2.9 1.4 1 0 0 1 1 1 0 Bax inhibitor 1 like DUF3984 PF13136.1 CDI87890.1 - 2.3 7.3 27.4 2.6 7.1 11.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3984) Glyco_transf_15 PF01793.11 CDI87890.1 - 2.4 7.0 9.5 3.7 6.4 4.9 2.0 2 0 0 2 2 2 0 Glycolipid 2-alpha-mannosyltransferase SelP_N PF04592.9 CDI87890.1 - 2.6 7.3 19.1 0.058 12.7 8.7 1.5 2 0 0 2 2 2 0 Selenoprotein P, N terminal region DUF4220 PF13968.1 CDI87890.1 - 3.5 6.6 8.9 1.6 7.7 4.8 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4220) Spore_coat_CotO PF14153.1 CDI87890.1 - 3.9 6.8 20.6 1 8.7 11.7 1.8 2 0 0 2 2 2 0 Spore coat protein CotO Myco_19_kDa PF05481.7 CDI87890.1 - 4.4 7.1 9.6 5.4 6.8 2.5 2.4 2 0 0 2 2 2 0 Mycobacterium 19 kDa lipoprotein antigen Bud13 PF09736.4 CDI87890.1 - 4.9 7.4 16.5 1.3 9.2 8.8 1.9 2 0 0 2 2 2 0 Pre-mRNA-splicing factor of RES complex Sec62 PF03839.11 CDI87890.1 - 7.9 5.8 8.1 12 5.2 5.6 1.3 1 0 0 1 1 1 0 Translocation protein Sec62 APC_CDC26 PF10471.4 CDI87891.1 - 0.0042 17.7 19.3 0.0057 17.3 13.4 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex APC subunit 1 CTNNB1_binding PF08347.6 CDI87891.1 - 0.0079 16.4 1.0 0.0084 16.3 0.7 1.1 1 0 0 1 1 1 1 N-terminal CTNNB1 binding EPL1 PF10513.4 CDI87891.1 - 0.0094 16.2 2.2 0.0094 16.2 1.6 1.1 1 0 0 1 1 1 1 Enhancer of polycomb-like SMN PF06003.7 CDI87891.1 - 0.023 13.7 0.2 0.027 13.5 0.2 1.1 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) DUF4557 PF15101.1 CDI87891.1 - 0.041 13.7 10.5 0.047 13.5 7.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) AUX_IAA PF02309.11 CDI87891.1 - 0.049 13.3 3.8 0.053 13.2 2.7 1.1 1 0 0 1 1 1 0 AUX/IAA family TAF1D PF15333.1 CDI87891.1 - 0.094 12.4 5.6 0.12 12.1 3.9 1.1 1 0 0 1 1 1 0 TATA box-binding protein-associated factor 1D DUF4407 PF14362.1 CDI87891.1 - 0.12 11.2 5.0 0.13 11.1 3.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Inhibitor_I71 PF12628.2 CDI87891.1 - 0.14 11.7 2.1 0.17 11.5 1.5 1.1 1 0 0 1 1 1 0 Falstatin, cysteine peptidase inhibitor Med15 PF09606.5 CDI87891.1 - 0.23 9.6 22.1 0.26 9.4 15.3 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal PAT1 PF09770.4 CDI87891.1 - 0.32 9.2 17.1 0.35 9.0 11.9 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Activator_LAG-3 PF11498.3 CDI87891.1 - 0.36 9.5 22.8 0.43 9.2 15.8 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 FLO_LFY PF01698.11 CDI87891.1 - 0.36 9.6 6.4 0.37 9.5 4.4 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein FCP1_C PF09309.5 CDI87891.1 - 0.38 10.0 9.2 0.63 9.3 6.4 1.3 1 0 0 1 1 1 0 FCP1, C-terminal Neur_chan_memb PF02932.11 CDI87891.1 - 0.54 10.1 1.9 0.59 9.9 1.3 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Pex14_N PF04695.8 CDI87891.1 - 0.65 10.0 9.8 0.8 9.7 6.8 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF2763 PF10961.3 CDI87891.1 - 0.78 10.1 4.3 1.4 9.3 3.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2763) FYTT PF07078.6 CDI87891.1 - 0.88 8.8 8.8 1.2 8.4 5.7 1.4 1 1 0 2 2 2 0 Forty-two-three protein XAP5 PF04921.9 CDI87891.1 - 0.94 8.9 7.0 1.1 8.7 4.9 1.1 1 0 0 1 1 1 0 XAP5, circadian clock regulator CDC45 PF02724.9 CDI87891.1 - 1.1 7.2 7.2 1.2 7.1 5.0 1.0 1 0 0 1 1 1 0 CDC45-like protein eIF-3_zeta PF05091.7 CDI87891.1 - 1.1 7.7 10.1 1.3 7.5 7.0 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) FimP PF09766.4 CDI87891.1 - 1.1 8.2 18.5 1.4 7.9 12.8 1.0 1 0 0 1 1 1 0 Fms-interacting protein RAB3GAP2_N PF14655.1 CDI87891.1 - 1.5 7.7 8.0 1.9 7.4 5.5 1.1 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Suf PF05843.9 CDI87891.1 - 1.6 8.4 9.6 1.7 8.3 6.6 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF912 PF06024.7 CDI87891.1 - 1.7 8.7 6.9 2.2 8.3 4.8 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) SpoVR PF04293.8 CDI87891.1 - 1.9 6.7 7.2 2.3 6.4 5.0 1.0 1 0 0 1 1 1 0 SpoVR like protein DUF3138 PF11336.3 CDI87891.1 - 1.9 6.5 7.6 2.3 6.2 5.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Folliculin PF11704.3 CDI87891.1 - 2.2 7.8 7.9 2.7 7.5 5.5 1.1 1 0 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport CENP-U PF13097.1 CDI87891.1 - 2.3 8.1 13.5 2.9 7.7 9.4 1.1 1 0 0 1 1 1 0 CENP-A nucleosome associated complex (NAC) subunit Pex16 PF08610.5 CDI87891.1 - 2.6 6.9 6.5 3.1 6.7 4.5 1.1 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) Ndc1_Nup PF09531.5 CDI87891.1 - 2.9 6.2 8.0 3.2 6.0 5.5 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Ctr PF04145.10 CDI87891.1 - 3.3 7.7 5.4 4.2 7.4 3.8 1.1 1 0 0 1 1 1 0 Ctr copper transporter family DUF1764 PF08576.5 CDI87891.1 - 3.4 8.4 13.9 4.2 8.1 9.6 1.1 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) DUF775 PF05603.7 CDI87891.1 - 3.9 6.9 9.6 4.8 6.6 6.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF775) ERF PF04404.7 CDI87891.1 - 4 6.9 15.0 5.3 6.5 10.4 1.2 1 0 0 1 1 1 0 ERF superfamily Shisa PF13908.1 CDI87891.1 - 4.5 7.4 10.0 5.6 7.1 6.9 1.1 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator DUF4175 PF13779.1 CDI87891.1 - 6.5 4.3 25.4 8.2 3.9 17.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Gag_spuma PF03276.9 CDI87891.1 - 6.6 4.9 17.5 7.7 4.7 12.1 1.1 1 0 0 1 1 1 0 Spumavirus gag protein Peptidase_S49_N PF08496.5 CDI87891.1 - 6.8 6.4 9.8 8.6 6.1 6.8 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal BAF1_ABF1 PF04684.8 CDI87891.1 - 7.2 5.3 18.7 8.3 5.1 12.9 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor DUF853 PF05872.7 CDI87891.1 - 7.9 4.6 8.3 9.2 4.4 5.8 1.0 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) Spt20 PF12090.3 CDI87891.1 - 8.7 5.6 11.7 11 5.3 8.1 1.2 1 0 0 1 1 1 0 Spt20 family Band_3_cyto PF07565.8 CDI87891.1 - 8.9 5.7 10.4 10 5.5 7.2 1.0 1 0 0 1 1 1 0 Band 3 cytoplasmic domain SRRM_C PF15230.1 CDI87891.1 - 9 6.4 7.0 15 5.7 4.9 1.3 1 0 0 1 1 1 0 Serine/arginine repetitive matrix protein C-terminus Tmemb_9 PF05434.6 CDI87892.1 - 0.003 17.2 4.7 0.003 17.2 3.2 5.2 3 1 2 5 5 5 1 TMEM9 Bap31 PF05529.7 CDI87892.1 - 0.029 13.8 1.2 0.029 13.8 0.8 4.0 3 1 0 4 4 4 0 B-cell receptor-associated protein 31-like SF3b1 PF08920.5 CDI87893.1 - 0.22 11.5 9.2 2.7 8.0 3.9 2.8 2 1 0 2 2 2 0 Splicing factor 3B subunit 1 Suf PF05843.9 CDI87894.1 - 0.0015 18.2 6.1 0.0015 18.2 4.2 1.1 1 0 0 1 1 1 1 Suppressor of forked protein (Suf) Ycf1 PF05758.7 CDI87894.1 - 0.0063 14.2 10.8 0.0068 14.2 7.5 1.1 1 0 0 1 1 1 1 Ycf1 SpoIIIAH PF12685.2 CDI87894.1 - 0.007 15.8 5.6 0.007 15.8 3.9 2.0 2 0 0 2 2 1 1 SpoIIIAH-like protein Kei1 PF08552.6 CDI87894.1 - 0.0071 16.0 6.5 0.011 15.4 4.5 1.4 1 0 0 1 1 1 1 Inositolphosphorylceramide synthase subunit Kei1 LMF1 PF06762.9 CDI87894.1 - 0.011 14.5 7.2 0.013 14.2 5.0 1.1 1 0 0 1 1 1 0 Lipase maturation factor Mem_trans PF03547.13 CDI87894.1 - 0.021 13.1 6.6 0.027 12.7 4.6 1.1 1 0 0 1 1 1 0 Membrane transport protein 7tm_7 PF08395.7 CDI87894.1 - 0.033 13.2 19.9 0.044 12.8 13.8 1.3 1 0 0 1 1 1 0 7tm Chemosensory receptor Shisa PF13908.1 CDI87894.1 - 0.046 13.9 6.1 0.061 13.4 4.2 1.2 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Neur_chan_memb PF02932.11 CDI87894.1 - 0.047 13.5 5.4 0.07 12.9 3.7 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region OmpH PF03938.9 CDI87894.1 - 0.075 12.9 26.7 0.079 12.8 18.5 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF4512 PF14975.1 CDI87894.1 - 0.14 13.0 3.5 0.27 12.0 2.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4512) SelP_N PF04592.9 CDI87894.1 - 0.18 11.1 13.0 0.24 10.7 9.0 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region DUF1510 PF07423.6 CDI87894.1 - 0.18 11.1 21.0 0.021 14.2 11.6 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1510) Pex24p PF06398.6 CDI87894.1 - 0.21 10.3 7.4 0.53 9.0 5.1 1.7 1 1 0 1 1 1 0 Integral peroxisomal membrane peroxin DUF3381 PF11861.3 CDI87894.1 - 0.38 10.2 19.8 0.64 9.5 13.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) BORG_CEP PF14957.1 CDI87894.1 - 0.43 11.4 7.8 0.63 10.9 5.4 1.2 1 0 0 1 1 1 0 Cdc42 effector Pex14_N PF04695.8 CDI87894.1 - 0.47 10.5 12.6 0.77 9.8 8.7 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF3260 PF11658.3 CDI87894.1 - 0.69 7.9 18.8 1 7.4 13.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3260) DUF2052 PF09747.4 CDI87894.1 - 0.72 9.7 19.6 1.1 9.1 13.6 1.3 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) AAA_11 PF13086.1 CDI87894.1 - 1.1 8.8 13.1 1.4 8.4 9.1 1.1 1 0 0 1 1 1 0 AAA domain UPF0565 PF10561.4 CDI87894.1 - 1.3 7.8 12.0 1.9 7.3 8.3 1.3 1 0 0 1 1 1 0 Uncharacterised protein family UPF0565 DDHD PF02862.12 CDI87894.1 - 2 8.1 11.9 2.6 7.7 8.3 1.2 1 0 0 1 1 1 0 DDHD domain YfhO PF09586.5 CDI87894.1 - 2.2 6.1 21.6 3.5 5.5 15.0 1.3 1 1 0 1 1 1 0 Bacterial membrane protein YfhO AIF_C PF14721.1 CDI87894.1 - 3.3 7.9 10.7 4.9 7.4 7.4 1.2 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Endonuc_Holl PF10107.4 CDI87894.1 - 3.8 7.1 17.5 7 6.3 12.2 1.5 1 0 0 1 1 1 0 Endonuclease related to archaeal Holliday junction resolvase Peptidase_S49_N PF08496.5 CDI87894.1 - 3.9 7.2 22.7 0.63 9.8 13.1 1.7 1 1 1 2 2 2 0 Peptidase family S49 N-terminal Spore_coat_CotO PF14153.1 CDI87894.1 - 5.2 6.4 24.0 7.7 5.9 16.6 1.2 1 0 0 1 1 1 0 Spore coat protein CotO TCP PF03634.8 CDI87894.1 - 5.8 7.2 16.4 8.2 6.7 11.4 1.2 1 0 0 1 1 1 0 TCP family transcription factor DUF2126 PF09899.4 CDI87894.1 - 6.8 4.5 14.1 8.9 4.2 9.7 1.0 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) SpoVR PF04293.8 CDI87894.1 - 7 4.8 16.4 9.3 4.4 11.4 1.1 1 0 0 1 1 1 0 SpoVR like protein MMR1 PF08505.5 CDI87894.1 - 7.6 6.4 15.7 9.4 6.1 10.9 1.1 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein Cys_Met_Meta_PP PF01053.15 CDI87896.1 - 1.5e-117 392.1 0.1 4e-67 226.1 0.0 2.0 2 0 0 2 2 2 2 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 CDI87896.1 - 1.4e-06 27.6 0.1 4.9e-06 25.8 0.0 1.8 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.16 CDI87896.1 - 0.0029 16.6 0.0 0.0055 15.7 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II Pex14_N PF04695.8 CDI87897.1 - 0.0016 18.4 3.5 0.0016 18.4 2.4 1.6 2 0 0 2 2 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Suf PF05843.9 CDI87897.1 - 0.045 13.4 4.3 0.063 12.9 2.9 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) PHD_3 PF13922.1 CDI87897.1 - 1.2 9.4 8.8 2.8 8.2 6.1 1.6 1 0 0 1 1 1 0 PHD domain of transcriptional enhancer, Asx FimP PF09766.4 CDI87897.1 - 1.6 7.6 10.4 2.3 7.2 7.2 1.1 1 0 0 1 1 1 0 Fms-interacting protein DUF4175 PF13779.1 CDI87897.1 - 8.4 3.9 18.9 12 3.4 13.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) CDK2AP PF09806.4 CDI87897.1 - 9 6.4 13.0 0.55 10.4 3.7 2.0 2 0 0 2 2 2 0 Cyclin-dependent kinase 2-associated protein DUF3682 PF12446.3 CDI87899.1 - 0.018 15.3 14.5 0.021 15.1 10.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) Gly-zipper_OmpA PF13436.1 CDI87899.1 - 0.076 12.6 7.0 0.094 12.3 4.9 1.1 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain DUF2360 PF10152.4 CDI87899.1 - 0.09 13.0 0.8 0.11 12.7 0.6 1.2 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) Shadoo PF14999.1 CDI87899.1 - 0.15 11.9 7.4 0.2 11.5 5.1 1.3 1 0 0 1 1 1 0 Shadow of prion protein, neuroprotective DUF2057 PF09829.4 CDI87899.1 - 0.25 10.9 3.7 0.31 10.6 2.5 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2057) Ashwin PF15323.1 CDI87899.1 - 0.29 11.1 2.2 0.34 10.8 1.5 1.0 1 0 0 1 1 1 0 Developmental protein Glycophorin_A PF01102.13 CDI87899.1 - 2.7 7.7 5.8 4.2 7.1 4.0 1.4 1 0 0 1 1 1 0 Glycophorin A Med3 PF11593.3 CDI87899.1 - 4.5 6.4 14.4 5.2 6.2 10.0 1.0 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Rubella_E2 PF05749.6 CDI87899.1 - 5.8 6.0 7.8 6.6 5.8 5.4 1.1 1 0 0 1 1 1 0 Rubella membrane glycoprotein E2 MRI PF15325.1 CDI87899.1 - 7.1 7.6 8.8 1.6e+02 3.2 6.1 2.0 1 1 0 1 1 1 0 Modulator of retrovirus infection PAT1 PF09770.4 CDI87901.1 - 0.59 8.3 47.6 0.84 7.8 33.0 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF4647 PF15504.1 CDI87901.1 - 8.3 5.1 15.8 12 4.5 11.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4647) Activator_LAG-3 PF11498.3 CDI87902.1 - 0.0028 16.5 13.2 0.0028 16.5 9.1 4.3 4 0 0 4 4 4 3 Transcriptional activator LAG-3 DUF726 PF05277.7 CDI87903.1 - 0.0031 16.4 0.9 0.0038 16.1 0.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Afi1 PF07792.7 CDI87903.1 - 0.032 14.2 3.7 0.11 12.4 0.2 2.1 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Med15 PF09606.5 CDI87903.1 - 0.41 8.7 18.0 0.62 8.1 12.5 1.4 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal RAB3GAP2_N PF14655.1 CDI87903.1 - 5.6 5.8 8.9 0.26 10.2 2.1 1.7 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus TMEM51 PF15345.1 CDI87904.1 - 0.03 14.0 0.8 0.035 13.8 0.6 1.0 1 0 0 1 1 1 0 Transmembrane protein 51 AMP-binding PF00501.23 CDI87904.1 - 0.038 12.3 0.1 0.04 12.3 0.0 1.1 1 0 0 1 1 1 0 AMP-binding enzyme DUF4175 PF13779.1 CDI87904.1 - 0.092 10.4 6.7 0.097 10.3 4.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Med15 PF09606.5 CDI87904.1 - 0.76 7.9 8.2 0.83 7.7 5.7 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal WASH-7_C PF14746.1 CDI87904.1 - 0.92 9.0 4.0 1.2 8.7 2.8 1.1 1 0 0 1 1 1 0 WASH complex subunit 7, C-terminal TALPID3 PF15324.1 CDI87904.1 - 1.4 6.1 12.3 1.7 5.9 8.5 1.0 1 0 0 1 1 1 0 Hedgehog signalling target Rrp15p PF07890.7 CDI87904.1 - 7 6.7 9.1 15 5.6 5.8 1.8 1 1 1 2 2 2 0 Rrp15p BAF1_ABF1 PF04684.8 CDI87904.1 - 7.8 5.2 10.9 8.3 5.1 7.6 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor GHMP_kinases_N PF00288.21 CDI87907.1 - 0.0013 18.7 5.8 0.44 10.6 0.2 3.2 2 0 0 2 2 2 2 GHMP kinases N terminal domain Scs3p PF10261.4 CDI87909.1 - 0.043 12.8 0.1 0.062 12.3 0.1 1.2 1 0 0 1 1 1 0 Inositol phospholipid synthesis and fat-storage-inducing TM PIG-U PF06728.8 CDI87909.1 - 0.049 12.4 3.3 0.11 11.2 0.1 2.1 2 0 0 2 2 2 0 GPI transamidase subunit PIG-U Mus7 PF09462.5 CDI87909.1 - 0.053 12.3 5.9 0.062 12.1 4.1 1.2 1 0 0 1 1 1 0 Mus7/MMS22 family SID-1_RNA_chan PF13965.1 CDI87909.1 - 0.48 8.5 2.7 0.76 7.8 1.7 1.4 1 1 0 1 1 1 0 dsRNA-gated channel SID-1 DUF2232 PF09991.4 CDI87909.1 - 3.3 6.6 10.3 2.8 6.8 3.5 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2232) Claudin_2 PF13903.1 CDI87909.1 - 4.5 6.9 19.6 1.4 8.6 3.7 2.2 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction TFIIA PF03153.8 CDI87909.1 - 6.3 6.5 22.8 9 6.0 15.8 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit WD40 PF00400.27 CDI87910.1 - 5.9e-05 22.8 0.0 0.00011 21.9 0.0 1.5 1 0 0 1 1 1 1 WD domain, G-beta repeat Activator_LAG-3 PF11498.3 CDI87910.1 - 0.00047 19.0 12.5 0.00075 18.3 8.7 1.4 1 0 0 1 1 1 1 Transcriptional activator LAG-3 Neur_chan_memb PF02932.11 CDI87910.1 - 0.0016 18.3 2.1 0.0025 17.7 1.5 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Med15 PF09606.5 CDI87910.1 - 0.023 12.8 22.2 0.028 12.6 15.4 1.3 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Wzz PF02706.10 CDI87910.1 - 0.27 11.0 7.4 0.69 9.7 5.1 1.6 1 0 0 1 1 1 0 Chain length determinant protein PAT1 PF09770.4 CDI87910.1 - 0.54 8.4 19.1 0.64 8.1 13.2 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 OMPdecase PF00215.19 CDI87910.1 - 8.5 5.7 9.0 11 5.2 6.3 1.3 1 0 0 1 1 1 0 Orotidine 5'-phosphate decarboxylase / HUMPS family SAPS PF04499.10 CDI87911.1 - 0.86 8.1 39.5 1.3 7.6 27.4 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF1777 PF08648.7 CDI87911.1 - 1.7 8.3 36.3 2.1 8.0 25.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) DUF4045 PF13254.1 CDI87911.1 - 4.5 6.4 43.8 6.3 5.9 30.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Utp14 PF04615.8 CDI87911.1 - 4.6 5.2 63.4 5.5 5.0 43.9 1.0 1 0 0 1 1 1 0 Utp14 protein DUF572 PF04502.8 CDI87911.1 - 6.6 5.8 50.6 7.9 5.6 35.1 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF572) RAP1 PF07218.6 CDI87915.1 - 0.03 12.4 8.4 0.037 12.1 5.8 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DUF1510 PF07423.6 CDI87915.1 - 0.17 11.2 32.5 0.68 9.2 7.6 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1510) DUF4366 PF14283.1 CDI87915.1 - 0.77 9.1 13.7 0.25 10.7 2.8 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4366) Neur_chan_memb PF02932.11 CDI87915.1 - 4.9 6.9 22.7 0.41 10.4 3.4 2.2 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region SPX PF03105.14 CDI87915.1 - 5.9 6.5 30.8 3.4 7.3 5.3 2.3 2 0 0 2 2 2 0 SPX domain Presenilin PF01080.12 CDI87915.1 - 6.5 5.4 23.2 0.31 9.8 2.3 2.3 2 0 0 2 2 2 0 Presenilin Hid1 PF12722.2 CDI87916.1 - 0.05 11.2 28.1 0.059 11.0 19.4 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Tim54 PF11711.3 CDI87916.1 - 0.055 12.0 12.5 0.067 11.7 8.6 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DDRGK PF09756.4 CDI87916.1 - 0.075 12.4 26.4 0.092 12.1 18.3 1.2 1 0 0 1 1 1 0 DDRGK domain SAPS PF04499.10 CDI87916.1 - 0.15 10.6 19.3 0.16 10.5 13.4 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Bud13 PF09736.4 CDI87916.1 - 0.16 12.2 24.0 0.22 11.8 16.7 1.3 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex Parvo_coat PF00740.13 CDI87916.1 - 0.16 10.9 28.2 0.18 10.7 19.5 1.0 1 0 0 1 1 1 0 Parvovirus coat protein VP2 DHHW PF14286.1 CDI87916.1 - 0.22 10.8 13.8 0.22 10.7 9.5 1.1 1 0 0 1 1 1 0 DHHW protein PIH1 PF08190.7 CDI87916.1 - 0.24 10.7 22.8 0.29 10.5 15.8 1.2 1 0 0 1 1 1 0 pre-RNA processing PIH1/Nop17 Raftlin PF15250.1 CDI87916.1 - 0.36 9.3 22.3 0.41 9.1 15.4 1.1 1 0 0 1 1 1 0 Raftlin Ycf1 PF05758.7 CDI87916.1 - 0.43 8.2 22.5 0.49 8.0 15.6 1.0 1 0 0 1 1 1 0 Ycf1 eIF-3_zeta PF05091.7 CDI87916.1 - 0.44 9.1 30.9 0.52 8.8 21.4 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF4045 PF13254.1 CDI87916.1 - 0.47 9.6 20.9 0.54 9.4 14.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) HSP70 PF00012.15 CDI87916.1 - 0.51 8.1 15.5 0.58 8.0 10.7 1.0 1 0 0 1 1 1 0 Hsp70 protein Spore_coat_CotO PF14153.1 CDI87916.1 - 0.54 9.6 31.3 0.69 9.3 21.7 1.2 1 0 0 1 1 1 0 Spore coat protein CotO PLRV_ORF5 PF01690.12 CDI87916.1 - 0.55 9.3 19.6 0.59 9.2 13.6 1.0 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein PAT1 PF09770.4 CDI87916.1 - 0.56 8.3 60.3 0.63 8.2 41.8 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Gag_spuma PF03276.9 CDI87916.1 - 0.91 7.7 35.0 1.2 7.3 24.3 1.2 1 0 0 1 1 1 0 Spumavirus gag protein DUF1510 PF07423.6 CDI87916.1 - 0.91 8.8 23.5 1.1 8.5 16.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) GPCR_chapero_1 PF11904.3 CDI87916.1 - 0.99 8.4 21.3 1.1 8.2 14.7 1.1 1 0 0 1 1 1 0 GPCR-chaperone SMN PF06003.7 CDI87916.1 - 1.3 8.0 5.4 1.9 7.5 3.8 1.3 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) DUF4175 PF13779.1 CDI87916.1 - 2.4 5.7 58.2 2.8 5.5 40.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Plasmodium_Vir PF05795.6 CDI87916.1 - 2.6 7.1 6.7 2.9 7.0 4.6 1.3 1 0 0 1 1 1 0 Plasmodium vivax Vir protein AvrE PF11725.3 CDI87916.1 - 2.9 4.7 24.9 3.4 4.5 17.3 1.0 1 0 0 1 1 1 0 Pathogenicity factor Rtf2 PF04641.7 CDI87916.1 - 3 6.9 25.2 3.7 6.6 17.4 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger RR_TM4-6 PF06459.7 CDI87916.1 - 3.1 7.6 20.1 4.1 7.2 14.0 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 TFIIA PF03153.8 CDI87916.1 - 3.5 7.4 44.0 4.1 7.1 30.5 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4228 PF14009.1 CDI87916.1 - 3.9 7.5 21.1 5.3 7.1 14.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4228) Caldesmon PF02029.10 CDI87916.1 - 4.2 5.6 20.0 4.8 5.4 13.9 1.0 1 0 0 1 1 1 0 Caldesmon DUF4638 PF15472.1 CDI87916.1 - 4.3 6.8 19.1 5.2 6.5 13.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) Peptidase_S15 PF02129.13 CDI87916.1 - 5.9 6.2 19.8 8.2 5.7 13.7 1.2 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) PPP4R2 PF09184.6 CDI87916.1 - 7.6 5.9 18.1 9.3 5.6 12.6 1.1 1 0 0 1 1 1 0 PPP4R2 BTV_NS2 PF04514.7 CDI87916.1 - 8.5 5.1 19.7 10 4.9 13.7 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 CRT10 PF08728.5 CDI87916.1 - 8.7 4.1 18.1 9.4 4.0 12.6 1.1 1 0 0 1 1 1 0 CRT10 TFIIF_alpha PF05793.7 CDI87917.1 - 0.43 8.8 46.4 0.052 11.9 28.8 1.8 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Draxin PF15550.1 CDI87917.1 - 4.6 6.7 38.3 0.16 11.5 20.5 2.1 2 0 0 2 2 2 0 Draxin LMBR1 PF04791.11 CDI87917.1 - 5.3 5.5 20.4 7.6 4.9 14.2 1.4 1 0 0 1 1 1 0 LMBR1-like membrane protein GATA PF00320.22 CDI87918.1 - 2.3e-08 33.2 3.5 2.3e-08 33.2 2.4 2.5 2 0 0 2 2 2 1 GATA zinc finger PAT1 PF09770.4 CDI87918.1 - 0.7 8.0 113.0 0.059 11.6 61.1 2.1 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 DUF4363 PF14276.1 CDI87919.1 - 0.27 10.9 2.6 1.9 8.2 0.0 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4363) Peptidase_S9 PF00326.16 CDI87923.1 - 0.0004 19.6 1.0 0.0005 19.3 0.7 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Spt20 PF12090.3 CDI87923.1 - 0.00064 19.1 1.6 0.0007 18.9 1.1 1.2 1 0 0 1 1 1 1 Spt20 family FimP PF09766.4 CDI87923.1 - 0.011 14.8 8.4 0.013 14.6 5.8 1.1 1 0 0 1 1 1 0 Fms-interacting protein Suf PF05843.9 CDI87923.1 - 0.012 15.3 4.4 0.013 15.2 3.1 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Pex14_N PF04695.8 CDI87923.1 - 0.012 15.6 10.6 0.012 15.6 7.4 1.6 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region PAT1 PF09770.4 CDI87923.1 - 0.018 13.3 12.0 0.017 13.3 8.3 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 RAB3GAP2_N PF14655.1 CDI87923.1 - 0.056 12.4 4.7 0.07 12.1 3.2 1.1 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus DUF4231 PF14015.1 CDI87923.1 - 0.061 13.3 3.4 0.092 12.7 2.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4231) Abhydrolase_5 PF12695.2 CDI87923.1 - 0.076 12.7 1.7 0.097 12.4 1.2 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Med15 PF09606.5 CDI87923.1 - 0.077 11.1 25.3 0.087 11.0 17.5 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal HemX PF04375.9 CDI87923.1 - 0.11 11.0 23.0 0.13 10.8 15.9 1.0 1 0 0 1 1 1 0 HemX TFIIA PF03153.8 CDI87923.1 - 0.12 12.1 15.6 0.15 11.9 10.8 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Tfb4 PF03850.9 CDI87923.1 - 0.33 10.1 5.2 0.44 9.7 3.6 1.2 1 0 0 1 1 1 0 Transcription factor Tfb4 MSP1_C PF07462.6 CDI87923.1 - 0.61 8.4 9.5 0.66 8.3 6.6 1.0 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Chorion_3 PF05387.6 CDI87923.1 - 0.9 8.9 20.1 1.1 8.6 13.9 1.1 1 0 0 1 1 1 0 Chorion family 3 Presenilin PF01080.12 CDI87923.1 - 1.1 7.9 3.3 1.1 8.0 2.3 1.1 1 0 0 1 1 1 0 Presenilin DUF3682 PF12446.3 CDI87923.1 - 1.3 9.3 22.9 2 8.7 15.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) DUF4557 PF15101.1 CDI87923.1 - 1.7 8.4 14.7 2.5 7.8 10.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) Serinc PF03348.10 CDI87923.1 - 2.2 6.9 7.0 2.6 6.6 4.8 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) DUF4179 PF13786.1 CDI87923.1 - 3.5 7.8 8.0 8.1 6.7 1.4 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4179) DUF4407 PF14362.1 CDI87923.1 - 4.2 6.2 20.4 5.5 5.8 14.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF3464 PF11947.3 CDI87923.1 - 4.5 6.7 7.9 1.5 8.2 3.8 1.4 2 0 0 2 2 1 0 Protein of unknown function (DUF3464) Adeno_PIX PF03955.9 CDI87923.1 - 4.8 7.7 12.2 0.36 11.3 3.0 2.2 2 0 0 2 2 2 0 Adenovirus hexon-associated protein (IX) FCP1_C PF09309.5 CDI87923.1 - 8 5.6 11.5 5.7 6.1 7.1 1.4 1 1 0 1 1 1 0 FCP1, C-terminal FHIPEP PF00771.15 CDI87924.1 - 0.46 8.7 20.9 0.56 8.4 14.5 1.1 1 0 0 1 1 1 0 FHIPEP family OATP PF03137.15 CDI87924.1 - 6.4 4.6 10.3 2.8 5.9 2.7 2.1 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Ribosomal_L18_c PF14204.1 CDI87926.1 - 4.7e-26 91.1 0.2 5.6e-26 90.9 0.1 1.1 1 0 0 1 1 1 1 Ribosomal L18 C-terminal region IFT43 PF15305.1 CDI87927.1 - 0.58 10.1 2.7 0.61 10.1 1.2 1.5 1 1 0 1 1 1 0 Intraflagellar transport protein 43 Ank_2 PF12796.2 CDI87928.1 - 6.3e-10 39.2 0.9 3.8e-09 36.7 0.6 2.3 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 CDI87928.1 - 2.1e-08 33.5 0.2 0.0011 18.6 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.1 CDI87928.1 - 5.5e-07 29.2 0.0 0.0017 18.4 0.0 3.5 3 0 0 3 3 3 1 Ankyrin repeat Ank_4 PF13637.1 CDI87928.1 - 6.1e-07 29.7 0.0 5.2e-06 26.8 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_5 PF13857.1 CDI87928.1 - 0.00049 20.2 0.0 0.0026 17.9 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeats (many copies) K_channel_TID PF07941.6 CDI87929.1 - 0.015 15.5 10.2 0.015 15.5 7.1 6.5 3 1 0 3 3 3 0 Potassium channel Kv1.4 tandem inactivation domain DUF3418 PF11898.3 CDI87930.1 - 0.049 12.0 4.6 0.058 11.7 3.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3418) DUF490 PF04357.8 CDI87930.1 - 0.46 9.5 2.7 0.72 8.8 1.9 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF490) Rifin_STEVOR PF02009.11 CDI87930.1 - 2.3 7.7 7.3 3.5 7.1 5.0 1.3 1 0 0 1 1 1 0 Rifin/stevor family SpaB_C PF14028.1 CDI87930.1 - 2.5 7.5 15.8 3.2 7.2 11.0 1.1 1 0 0 1 1 1 0 SpaB C-terminal domain SGT1 PF07093.6 CDI87931.1 - 4.3 5.5 34.2 5.1 5.3 23.7 1.0 1 0 0 1 1 1 0 SGT1 protein Nop14 PF04147.7 CDI87931.1 - 5.6 4.7 61.4 1.4e+03 -3.3 42.5 2.0 1 1 0 1 1 1 0 Nop14-like family DUF1082 PF06449.6 CDI87932.1 - 0.52 10.2 1.1 36 4.3 0.0 3.4 4 0 0 4 4 4 0 Mitochondrial domain of unknown function (DUF1082) SprA-related PF12118.3 CDI87933.1 - 0.0063 15.8 13.7 0.0089 15.3 9.5 1.2 1 0 0 1 1 1 1 SprA-related family THRAP3_BCLAF1 PF15440.1 CDI87933.1 - 0.018 13.7 16.4 0.02 13.6 11.3 1.0 1 0 0 1 1 1 0 THRAP3/BCLAF1 family YscJ_FliF_C PF08345.6 CDI87933.1 - 0.042 13.8 9.4 0.055 13.4 6.5 1.3 1 0 0 1 1 1 0 Flagellar M-ring protein C-terminal SOBP PF15279.1 CDI87933.1 - 0.044 14.1 5.6 0.045 14.1 3.9 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein Pneumo_att_G PF05539.6 CDI87933.1 - 0.11 11.7 9.4 0.12 11.7 6.5 1.0 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G CDC45 PF02724.9 CDI87933.1 - 0.15 10.0 7.4 0.17 9.8 5.1 1.1 1 0 0 1 1 1 0 CDC45-like protein Sec3_C PF09763.4 CDI87933.1 - 0.17 9.9 6.0 0.17 10.0 4.2 1.2 1 0 0 1 1 1 0 Exocyst complex component Sec3 SRP-alpha_N PF04086.8 CDI87933.1 - 0.21 10.9 9.6 0.22 10.8 6.6 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal CAF-1_p150 PF11600.3 CDI87933.1 - 0.22 10.8 17.5 0.3 10.4 12.2 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Apt1 PF10351.4 CDI87933.1 - 0.23 10.2 16.3 0.27 10.0 11.3 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain ORC6 PF05460.8 CDI87933.1 - 0.31 10.0 9.2 0.38 9.8 6.4 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) SOG2 PF10428.4 CDI87933.1 - 0.5 8.9 11.4 0.52 8.9 7.9 1.0 1 0 0 1 1 1 0 RAM signalling pathway protein DUF2201_N PF13203.1 CDI87933.1 - 0.51 9.4 10.0 0.71 8.9 6.9 1.3 1 0 0 1 1 1 0 Putative metallopeptidase domain DUF1675 PF07897.6 CDI87933.1 - 0.52 10.1 14.9 0.64 9.8 10.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) Macoilin PF09726.4 CDI87933.1 - 0.55 8.4 18.0 0.6 8.3 12.5 1.1 1 0 0 1 1 1 0 Transmembrane protein DDHD PF02862.12 CDI87933.1 - 0.59 9.9 9.4 0.72 9.6 6.5 1.1 1 0 0 1 1 1 0 DDHD domain Ribosomal_60s PF00428.14 CDI87933.1 - 0.74 10.2 12.8 1.9 8.9 8.9 1.6 1 0 0 1 1 1 0 60s Acidic ribosomal protein Hid1 PF12722.2 CDI87933.1 - 0.8 7.3 10.1 0.81 7.2 7.0 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein FLO_LFY PF01698.11 CDI87933.1 - 0.8 8.4 3.9 0.92 8.2 2.7 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein Raftlin PF15250.1 CDI87933.1 - 1 7.7 7.3 1.2 7.5 5.0 1.0 1 0 0 1 1 1 0 Raftlin DUF566 PF04484.7 CDI87933.1 - 1.1 8.7 16.8 1.2 8.5 11.6 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF566) Herpes_DNAp_acc PF04929.7 CDI87933.1 - 2.3 7.1 8.3 2.8 6.8 5.7 1.0 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Sec10 PF07393.6 CDI87933.1 - 2.8 6.0 7.7 2.9 5.9 5.3 1.1 1 0 0 1 1 1 0 Exocyst complex component Sec10 DUF2217 PF10265.4 CDI87933.1 - 3.1 6.4 10.3 3 6.4 7.2 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) Paramyxo_C PF01692.13 CDI87933.1 - 3.5 7.1 7.7 4.4 6.8 5.3 1.1 1 0 0 1 1 1 0 Paramyxovirus non-structural protein c PPP4R2 PF09184.6 CDI87933.1 - 4.1 6.8 11.7 5.3 6.4 8.1 1.1 1 0 0 1 1 1 0 PPP4R2 Peptidase_S64 PF08192.6 CDI87933.1 - 5.4 5.2 10.3 5.3 5.2 7.2 1.0 1 0 0 1 1 1 0 Peptidase family S64 GPCR_chapero_1 PF11904.3 CDI87933.1 - 5.5 6.0 9.1 6.8 5.7 6.3 1.1 1 0 0 1 1 1 0 GPCR-chaperone Presenilin PF01080.12 CDI87933.1 - 6.2 5.5 7.2 6.4 5.4 5.0 1.2 1 0 0 1 1 1 0 Presenilin HGTP_anticodon2 PF12745.2 CDI87933.1 - 8.2 5.4 10.6 11 5.1 7.4 1.1 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs Period_C PF12114.3 CDI87933.1 - 8.6 5.9 22.6 12 5.4 15.7 1.2 1 0 0 1 1 1 0 Period protein 2/3C-terminal region Claudin_2 PF13903.1 CDI87934.1 - 0.0077 15.9 6.0 0.0082 15.8 4.2 1.0 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction NPDC1 PF06809.6 CDI87934.1 - 0.043 12.6 9.8 0.044 12.5 6.8 1.0 1 0 0 1 1 1 0 Neural proliferation differentiation control-1 protein (NPDC1) DUF3357 PF11837.3 CDI87934.1 - 0.056 13.3 1.5 0.066 13.0 1.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) Abhydrolase_9_N PF15420.1 CDI87934.1 - 0.078 12.7 3.0 0.088 12.5 2.1 1.1 1 0 0 1 1 1 0 Alpha/beta-hydrolase family N-terminus Med15 PF09606.5 CDI87934.1 - 0.22 9.7 18.5 0.22 9.6 12.8 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Cu_amine_oxid PF01179.15 CDI87934.1 - 0.23 10.1 3.1 0.28 9.8 2.1 1.0 1 0 0 1 1 1 0 Copper amine oxidase, enzyme domain DUF4231 PF14015.1 CDI87934.1 - 0.27 11.2 4.7 0.37 10.7 3.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4231) Hamartin PF04388.7 CDI87934.1 - 0.28 9.7 5.1 0.29 9.7 3.5 1.0 1 0 0 1 1 1 0 Hamartin protein AIRC PF00731.15 CDI87934.1 - 0.36 10.1 7.6 0.44 9.8 5.3 1.3 1 0 0 1 1 1 0 AIR carboxylase R_equi_Vir PF05526.6 CDI87934.1 - 4.8 6.7 7.2 5.3 6.6 5.0 1.2 1 0 0 1 1 1 0 Rhodococcus equi virulence-associated protein DUF2637 PF10935.3 CDI87934.1 - 4.8 7.1 13.4 32 4.4 9.2 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2637) Robl_LC7 PF03259.12 CDI87934.1 - 4.9 6.7 10.3 5.5 6.6 2.1 2.2 1 1 1 2 2 2 0 Roadblock/LC7 domain DOR PF14839.1 CDI87934.1 - 5.4 6.6 10.2 5.5 6.6 7.0 1.0 1 0 0 1 1 1 0 DOR family UPF0172 PF03665.8 CDI87935.1 - 0.18 11.2 8.2 0.22 10.9 5.7 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0172) DUF2175 PF09943.4 CDI87935.1 - 0.54 10.3 7.7 0.55 10.3 5.0 1.4 1 1 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2175) Corona_nucleoca PF00937.13 CDI87935.1 - 0.92 8.3 19.8 0.97 8.3 13.8 1.1 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein RbsD_FucU PF05025.8 CDI87935.1 - 2.5 8.4 6.3 3 8.1 4.3 1.2 1 0 0 1 1 1 0 RbsD / FucU transport protein family Suc_Fer-like PF06999.7 CDI87935.1 - 2.6 7.9 9.4 3.1 7.7 6.5 1.3 1 1 0 1 1 1 0 Sucrase/ferredoxin-like CemA PF03040.9 CDI87935.1 - 5.5 6.5 10.7 6 6.3 7.4 1.2 1 0 0 1 1 1 0 CemA family BAF1_ABF1 PF04684.8 CDI87936.1 - 0.0016 17.4 16.8 0.0016 17.4 11.7 7.7 4 2 3 7 7 7 1 BAF1 / ABF1 chromatin reorganising factor Ribosomal_60s PF00428.14 CDI87937.1 - 0.036 14.4 4.5 0.073 13.4 3.1 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein Zip PF02535.17 CDI87938.1 - 0.031 13.2 17.5 0.037 13.0 12.1 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter DUF4366 PF14283.1 CDI87938.1 - 0.32 10.3 4.0 0.46 9.8 2.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) Utp14 PF04615.8 CDI87938.1 - 1.1 7.3 22.6 1.3 7.1 15.7 1.0 1 0 0 1 1 1 0 Utp14 protein MRP-S31 PF15433.1 CDI87938.1 - 1.5 8.1 20.2 2 7.7 14.0 1.1 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 Dehydrin PF00257.14 CDI87938.1 - 2.4 8.4 30.8 1.5 9.1 9.3 2.1 2 0 0 2 2 2 0 Dehydrin Macoilin PF09726.4 CDI87938.1 - 2.6 6.2 24.8 3.5 5.7 17.2 1.2 1 0 0 1 1 1 0 Transmembrane protein DUF1779 PF08680.5 CDI87938.1 - 3.2 7.5 15.4 3.6 7.3 10.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1779) Rtf2 PF04641.7 CDI87938.1 - 3.4 6.7 16.5 4.8 6.2 11.5 1.2 1 0 0 1 1 1 0 Rtf2 RING-finger CDC45 PF02724.9 CDI87938.1 - 3.8 5.4 17.2 4.5 5.1 11.9 1.0 1 0 0 1 1 1 0 CDC45-like protein DUF1675 PF07897.6 CDI87938.1 - 4.7 6.9 21.5 5.8 6.6 14.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) BTV_NS2 PF04514.7 CDI87938.1 - 5.9 5.6 14.2 7 5.4 9.8 1.0 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 FAM60A PF15396.1 CDI87938.1 - 7.5 6.2 17.7 11 5.6 12.3 1.3 1 0 0 1 1 1 0 Protein Family FAM60A DUF2146 PF10220.4 CDI87938.1 - 9.7 4.0 20.9 12 3.7 14.5 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2146) zf-C2HC_2 PF13913.1 CDI87939.1 - 0.0046 16.5 1.8 0.011 15.3 1.3 1.7 1 0 0 1 1 1 1 zinc-finger of a C2HC-type zf-C2H2 PF00096.21 CDI87939.1 - 0.074 13.4 0.5 0.16 12.3 0.3 1.6 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-trcl PF13451.1 CDI87939.1 - 3.2 7.4 12.9 0.19 11.3 0.5 3.6 3 1 1 4 4 4 0 Probable zinc-binding domain Pkinase PF00069.20 CDI87940.1 - 4.3e-37 127.6 0.0 5.3e-37 127.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CDI87940.1 - 2.7e-15 56.1 0.0 3.3e-15 55.8 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 CDI87940.1 - 0.0062 15.6 0.0 0.016 14.2 0.0 1.7 1 1 1 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family DNA_ligase_aden PF01653.13 CDI87940.1 - 0.044 12.7 0.0 0.063 12.2 0.0 1.2 1 0 0 1 1 1 0 NAD-dependent DNA ligase adenylation domain AAA_23 PF13476.1 CDI87941.1 - 0.00041 20.7 23.5 0.00049 20.4 16.3 1.1 1 0 0 1 1 1 1 AAA domain RskA PF10099.4 CDI87941.1 - 0.00073 19.3 2.8 0.0011 18.7 2.0 1.3 1 0 0 1 1 1 1 Anti-sigma-K factor rskA Ycf1 PF05758.7 CDI87941.1 - 0.0016 16.2 15.8 0.002 15.9 10.9 1.1 1 0 0 1 1 1 1 Ycf1 DUF4557 PF15101.1 CDI87941.1 - 0.0026 17.6 23.3 0.0037 17.1 16.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4557) Ribosomal_60s PF00428.14 CDI87941.1 - 0.0034 17.7 2.7 0.0068 16.7 1.9 1.6 1 0 0 1 1 1 1 60s Acidic ribosomal protein Raftlin PF15250.1 CDI87941.1 - 0.032 12.7 17.6 0.032 12.7 12.2 1.2 1 0 0 1 1 1 0 Raftlin RR_TM4-6 PF06459.7 CDI87941.1 - 0.15 11.9 20.7 0.18 11.6 14.3 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SprA-related PF12118.3 CDI87941.1 - 0.26 10.5 59.5 0.49 9.6 41.2 1.4 1 1 0 1 1 1 0 SprA-related family GAGA_bind PF06217.7 CDI87941.1 - 0.5 10.2 16.6 0.55 10.1 11.5 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family Trp_oprn_chp PF09534.5 CDI87941.1 - 0.62 9.6 6.9 1 8.9 4.8 1.4 1 1 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Spt5_N PF11942.3 CDI87941.1 - 0.7 10.5 21.2 1.1 9.8 14.7 1.3 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal LIN37 PF15306.1 CDI87941.1 - 0.85 9.5 18.5 1.5 8.8 12.8 1.3 1 0 0 1 1 1 0 LIN37 Usp PF00582.21 CDI87941.1 - 1 9.5 4.1 1.6 8.9 2.9 1.3 1 0 0 1 1 1 0 Universal stress protein family FLO_LFY PF01698.11 CDI87941.1 - 1.4 7.6 18.0 1.8 7.3 12.5 1.2 1 0 0 1 1 1 0 Floricaula / Leafy protein Peptidase_S49_N PF08496.5 CDI87941.1 - 1.5 8.5 13.7 2.9 7.6 9.5 1.5 1 0 0 1 1 1 0 Peptidase family S49 N-terminal NARP1 PF12569.3 CDI87941.1 - 3 6.5 19.4 4.1 6.0 13.5 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Cgr1 PF03879.9 CDI87942.1 - 0.051 13.7 17.6 0.062 13.4 12.2 1.1 1 0 0 1 1 1 0 Cgr1 family TCP PF03634.8 CDI87942.1 - 2.2 8.6 18.4 2.7 8.3 12.7 1.1 1 0 0 1 1 1 0 TCP family transcription factor PAT1 PF09770.4 CDI87942.1 - 4.8 5.2 26.9 5 5.2 18.6 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 FCP1_C PF09309.5 CDI87942.1 - 5.1 6.3 18.5 5.6 6.1 12.8 1.1 1 0 0 1 1 1 0 FCP1, C-terminal Dynamin_N PF00350.18 CDI87942.1 - 6.2 6.6 10.7 7.2 6.3 7.4 1.1 1 0 0 1 1 1 0 Dynamin family GBP_C PF02841.9 CDI87942.1 - 6.9 5.7 21.3 7.4 5.6 14.7 1.0 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain TFIIA PF03153.8 CDI87942.1 - 7.7 6.3 25.8 8.9 6.0 17.9 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RAB3GAP2_N PF14655.1 CDI87942.1 - 8.7 5.2 11.2 9.6 5.0 7.8 1.2 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus DUF853 PF05872.7 CDI87942.1 - 9.3 4.4 12.9 9.9 4.3 8.9 1.0 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) YqfQ PF14181.1 CDI87942.1 - 9.3 6.2 18.5 11 6.0 12.8 1.3 1 0 0 1 1 1 0 YqfQ-like protein eIF3_subunit PF08597.5 CDI87942.1 - 9.7 5.6 20.0 11 5.4 13.8 1.0 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit ketoacyl-synt PF00109.21 CDI87944.1 - 2.1e-84 282.9 0.7 4.5e-84 281.9 0.5 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain AMP-binding PF00501.23 CDI87944.1 - 1.3e-72 244.5 0.0 2.5e-72 243.5 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme PS-DH PF14765.1 CDI87944.1 - 1.4e-45 155.7 0.1 5.8e-33 114.3 0.0 2.4 2 0 0 2 2 2 2 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.17 CDI87944.1 - 2e-42 143.7 0.0 4.9e-42 142.5 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Acyl_transf_1 PF00698.16 CDI87944.1 - 2e-28 99.6 0.0 3.7e-28 98.8 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain PP-binding PF00550.20 CDI87944.1 - 1.4e-10 41.2 0.3 3.8e-10 39.8 0.2 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site ADH_N PF08240.7 CDI87944.1 - 9.2e-08 31.8 0.0 3.7e-07 29.8 0.0 2.1 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Thiolase_N PF00108.18 CDI87944.1 - 8.9e-05 21.6 1.6 0.00016 20.7 0.1 1.9 2 0 0 2 2 2 1 Thiolase, N-terminal domain AMP-binding_C_2 PF14535.1 CDI87944.1 - 0.00091 19.2 0.0 0.0026 17.7 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain 5-nucleotidase PF06189.7 CDI87944.1 - 0.65 8.7 0.0 1.2 7.8 0.0 1.3 1 0 0 1 1 1 0 5'-nucleotidase HEAT PF02985.17 CDI87945.1 - 0.0094 15.9 2.1 0.035 14.1 0.0 3.3 2 0 0 2 2 2 1 HEAT repeat SR-25 PF10500.4 CDI87945.1 - 0.017 14.6 6.0 0.017 14.6 4.1 3.3 4 0 0 4 4 4 0 Nuclear RNA-splicing-associated protein YebO PF13974.1 CDI87945.1 - 0.12 12.1 2.8 0.37 10.6 1.9 1.9 1 0 0 1 1 1 0 YebO-like protein BNIP3 PF06553.7 CDI87945.1 - 9.3 5.5 14.2 2.9 7.2 2.1 2.3 2 0 0 2 2 2 0 BNIP3 PAT1 PF09770.4 CDI87946.1 - 2.5 6.2 72.2 3.5 5.7 50.0 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF4131 PF13567.1 CDI87947.1 - 4.5e-06 26.1 6.3 4.8e-06 26.1 4.4 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4131) Pex24p PF06398.6 CDI87947.1 - 1.7e-05 23.8 1.6 2e-05 23.5 1.1 1.2 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin DUF1510 PF07423.6 CDI87947.1 - 2e-05 24.0 3.3 2.5e-05 23.7 2.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) DUF2244 PF10003.4 CDI87947.1 - 0.00014 21.2 0.1 0.00016 21.1 0.0 1.0 1 0 0 1 1 1 1 Integral membrane protein (DUF2244) IncA PF04156.9 CDI87947.1 - 0.00018 21.1 23.7 0.00022 20.8 16.4 1.1 1 0 0 1 1 1 1 IncA protein YfhO PF09586.5 CDI87947.1 - 0.00033 18.8 12.9 0.00035 18.7 9.0 1.0 1 0 0 1 1 1 1 Bacterial membrane protein YfhO Peptidase_S49_N PF08496.5 CDI87947.1 - 0.00061 19.6 9.9 0.00082 19.2 6.8 1.1 1 0 0 1 1 1 1 Peptidase family S49 N-terminal FA_desaturase PF00487.19 CDI87947.1 - 0.00067 19.1 2.0 0.00081 18.9 1.4 1.2 1 0 0 1 1 1 1 Fatty acid desaturase Neur_chan_memb PF02932.11 CDI87947.1 - 0.00083 19.3 7.8 0.001 19.0 5.4 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Nucleoside_tran PF01733.13 CDI87947.1 - 0.00093 18.4 2.0 0.0011 18.2 1.4 1.2 1 0 0 1 1 1 1 Nucleoside transporter DUF3260 PF11658.3 CDI87947.1 - 0.001 17.2 12.4 0.0012 17.1 8.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3260) SID-1_RNA_chan PF13965.1 CDI87947.1 - 0.0011 17.2 4.9 0.0012 17.0 3.4 1.1 1 0 0 1 1 1 1 dsRNA-gated channel SID-1 EcsB PF05975.7 CDI87947.1 - 0.0027 16.2 5.5 0.003 16.1 3.8 1.2 1 0 0 1 1 1 1 Bacterial ABC transporter protein EcsB Reticulon PF02453.12 CDI87947.1 - 0.0029 17.2 1.1 0.0036 16.9 0.7 1.2 1 0 0 1 1 1 1 Reticulon Ycf1 PF05758.7 CDI87947.1 - 0.0041 14.9 6.9 0.0048 14.7 4.8 1.0 1 0 0 1 1 1 1 Ycf1 Shisa PF13908.1 CDI87947.1 - 0.0051 17.0 7.2 0.0058 16.8 5.0 1.0 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator DUF3450 PF11932.3 CDI87947.1 - 0.0067 15.7 20.0 0.0082 15.4 13.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) SKN1 PF03935.10 CDI87947.1 - 0.016 13.3 3.9 0.019 13.1 2.7 1.0 1 0 0 1 1 1 0 Beta-glucan synthesis-associated protein (SKN1) Neur PF00064.13 CDI87947.1 - 0.032 12.3 4.0 0.033 12.2 2.7 1.0 1 0 0 1 1 1 0 Neuraminidase FPN1 PF06963.7 CDI87947.1 - 0.035 12.4 3.8 0.04 12.3 2.6 1.1 1 0 0 1 1 1 0 Ferroportin1 (FPN1) MacB_PCD PF12704.2 CDI87947.1 - 0.038 13.5 1.1 0.045 13.3 0.7 1.1 1 0 0 1 1 1 0 MacB-like periplasmic core domain Choline_transpo PF04515.7 CDI87947.1 - 0.044 12.5 0.0 0.053 12.2 0.0 1.2 1 0 0 1 1 1 0 Plasma-membrane choline transporter G0-G1_switch_2 PF15103.1 CDI87947.1 - 0.056 13.6 5.5 0.082 13.1 3.8 1.3 1 0 0 1 1 1 0 G0/G1 switch protein 2 Folate_carrier PF01770.13 CDI87947.1 - 0.057 11.9 10.5 0.068 11.6 7.3 1.0 1 0 0 1 1 1 0 Reduced folate carrier LRR19-TM PF15176.1 CDI87947.1 - 0.059 13.0 0.1 0.073 12.7 0.1 1.3 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain FA_hydroxylase PF04116.8 CDI87947.1 - 0.063 13.6 5.9 0.073 13.4 4.1 1.1 1 0 0 1 1 1 0 Fatty acid hydroxylase superfamily Pex14_N PF04695.8 CDI87947.1 - 0.072 13.1 13.9 0.099 12.6 9.6 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Mem_trans PF03547.13 CDI87947.1 - 0.08 11.2 7.6 0.1 10.8 5.3 1.3 1 0 0 1 1 1 0 Membrane transport protein Endonuc_Holl PF10107.4 CDI87947.1 - 0.12 12.0 12.4 0.15 11.7 8.6 1.2 1 0 0 1 1 1 0 Endonuclease related to archaeal Holliday junction resolvase DUF2607 PF10795.4 CDI87947.1 - 0.15 11.9 13.8 0.2 11.4 9.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2607) ATG22 PF11700.3 CDI87947.1 - 0.16 10.4 1.8 0.19 10.1 1.3 1.1 1 0 0 1 1 1 0 Vacuole effluxer Atg22 like Baculo_PP31 PF05311.6 CDI87947.1 - 0.16 11.1 8.6 0.18 11.0 5.9 1.0 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) DUF3381 PF11861.3 CDI87947.1 - 0.17 11.3 12.7 0.21 11.0 8.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) RHD3 PF05879.7 CDI87947.1 - 0.21 9.4 10.3 0.25 9.2 7.2 1.0 1 0 0 1 1 1 0 Root hair defective 3 GTP-binding protein (RHD3) DUF4512 PF14975.1 CDI87947.1 - 0.22 12.3 2.6 0.29 11.9 1.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4512) SpoIIIAH PF12685.2 CDI87947.1 - 0.23 10.9 14.1 0.5 9.8 9.8 1.6 1 1 0 1 1 1 0 SpoIIIAH-like protein RskA PF10099.4 CDI87947.1 - 0.29 10.8 8.2 0.57 9.8 5.7 1.6 1 1 0 1 1 1 0 Anti-sigma-K factor rskA DUF3810 PF12725.2 CDI87947.1 - 0.45 9.3 6.4 0.6 8.9 4.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) R_equi_Vir PF05526.6 CDI87947.1 - 0.45 10.1 3.3 0.53 9.9 2.3 1.1 1 0 0 1 1 1 0 Rhodococcus equi virulence-associated protein LIM_bind PF01803.11 CDI87947.1 - 0.47 9.5 15.6 0.54 9.3 10.8 1.1 1 0 0 1 1 1 0 LIM-domain binding protein Wzy_C PF04932.10 CDI87947.1 - 0.49 10.1 3.1 0.63 9.8 2.1 1.3 1 1 0 1 1 1 0 O-Antigen ligase PRA1 PF03208.14 CDI87947.1 - 0.65 9.3 9.0 0.81 9.0 6.2 1.4 1 1 0 1 1 1 0 PRA1 family protein CobD_Cbib PF03186.8 CDI87947.1 - 0.7 8.9 5.0 0.77 8.7 3.4 1.1 1 0 0 1 1 1 0 CobD/Cbib protein CD20 PF04103.10 CDI87947.1 - 0.76 9.6 10.3 1.3 8.9 6.8 1.7 1 1 0 1 1 1 0 CD20-like family DUF1312 PF07009.6 CDI87947.1 - 0.79 9.5 6.1 1.5 8.6 4.3 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1312) Band_3_cyto PF07565.8 CDI87947.1 - 1.1 8.7 18.0 1.4 8.4 12.5 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain AIF_C PF14721.1 CDI87947.1 - 1.3 9.2 8.5 1.5 9.0 5.9 1.1 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term DUF2422 PF10337.4 CDI87947.1 - 1.4 7.6 19.3 2 7.1 13.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2422) ABC_membrane_3 PF13748.1 CDI87947.1 - 1.6 7.6 10.8 2 7.4 7.5 1.3 1 0 0 1 1 1 0 ABC transporter transmembrane region DDHD PF02862.12 CDI87947.1 - 1.9 8.2 9.4 2.2 8.0 6.5 1.1 1 0 0 1 1 1 0 DDHD domain DUF2254 PF10011.4 CDI87947.1 - 2.3 6.5 8.8 3 6.2 6.0 1.3 1 1 0 1 1 1 0 Predicted membrane protein (DUF2254) DUF2514 PF10721.4 CDI87947.1 - 2.3 7.8 17.7 3.6 7.2 12.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2514) Chordopox_A33R PF05966.7 CDI87947.1 - 2.9 6.6 9.1 4.3 6.0 6.3 1.4 1 1 0 1 1 1 0 Chordopoxvirus A33R protein GNT-I PF03071.10 CDI87947.1 - 3.1 6.2 10.4 3.8 5.9 7.2 1.0 1 0 0 1 1 1 0 GNT-I family Stig1 PF04885.8 CDI87947.1 - 3.4 7.8 10.2 4.4 7.4 7.1 1.4 1 1 0 1 1 1 0 Stigma-specific protein, Stig1 FimP PF09766.4 CDI87947.1 - 3.7 6.5 23.7 4.3 6.2 16.4 1.1 1 0 0 1 1 1 0 Fms-interacting protein TraP PF07296.6 CDI87947.1 - 3.8 6.4 5.8 5.3 5.9 4.0 1.4 1 1 0 1 1 1 0 TraP protein Tetraspannin PF00335.15 CDI87947.1 - 3.8 6.7 15.5 6.5 5.9 10.8 1.4 1 1 0 1 1 1 0 Tetraspanin family CemA PF03040.9 CDI87947.1 - 4.4 6.8 14.6 5.5 6.5 10.1 1.1 1 0 0 1 1 1 0 CemA family GDE_N PF12439.3 CDI87947.1 - 4.8 6.3 12.2 6 6.0 8.4 1.1 1 0 0 1 1 1 0 Glycogen debranching enzyme N terminal Herpes_LMP1 PF05297.6 CDI87947.1 - 5.1 5.9 9.9 5.8 5.7 6.9 1.2 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) Sigma_reg_N PF13800.1 CDI87947.1 - 5.1 7.1 6.4 7.3 6.6 4.4 1.5 1 1 0 1 1 1 0 Sigma factor regulator N-terminal Cyclin_C PF02984.14 CDI87947.1 - 5.4 6.9 9.6 6.9 6.6 6.7 1.2 1 0 0 1 1 1 0 Cyclin, C-terminal domain Suf PF05843.9 CDI87947.1 - 6 6.5 18.4 8.2 6.0 12.8 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) TRAP_alpha PF03896.11 CDI87947.1 - 6.4 5.6 14.6 13 4.7 10.1 1.5 1 1 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit ABC_membrane PF00664.18 CDI87947.1 - 6.8 6.0 11.8 5.3 6.3 7.5 1.2 1 1 0 1 1 1 0 ABC transporter transmembrane region Peptidase_U57 PF05582.7 CDI87947.1 - 7.5 5.4 10.4 8.3 5.2 7.2 1.0 1 0 0 1 1 1 0 YabG peptidase U57 DUF2140 PF09911.4 CDI87947.1 - 8.1 5.5 13.8 13 4.8 9.5 1.5 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2140) Peptidase_M41 PF01434.13 CDI87948.1 - 2.2e-09 37.1 0.1 2.2e-09 37.1 0.1 2.4 3 0 0 3 3 3 1 Peptidase family M41 Calici_coat_C PF08435.6 CDI87948.1 - 0.38 10.0 4.2 0.46 9.7 2.6 1.3 1 1 0 1 1 1 0 Calicivirus coat protein C-terminal Nop14 PF04147.7 CDI87949.1 - 0.11 10.3 73.9 0.16 9.9 51.3 1.2 1 0 0 1 1 1 0 Nop14-like family DALR_2 PF09190.6 CDI87949.1 - 2.3 8.5 6.1 4.4 7.6 0.6 2.8 2 1 0 2 2 2 0 DALR domain DUF572 PF04502.8 CDI87949.1 - 7.7 5.6 47.1 13 4.9 32.6 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) RskA PF10099.4 CDI87950.1 - 0.0024 17.6 10.5 0.003 17.3 7.3 1.2 1 0 0 1 1 1 1 Anti-sigma-K factor rskA MDFI PF15316.1 CDI87950.1 - 0.19 11.7 11.9 0.22 11.4 8.3 1.2 1 0 0 1 1 1 0 MyoD family inhibitor RAMP4 PF06624.7 CDI87950.1 - 0.32 10.5 5.0 0.094 12.2 0.7 2.2 2 1 0 2 2 2 0 Ribosome associated membrane protein RAMP4 Ribosomal_60s PF00428.14 CDI87950.1 - 0.74 10.2 7.8 1.1 9.7 5.4 1.4 1 1 0 1 1 1 0 60s Acidic ribosomal protein Presenilin PF01080.12 CDI87950.1 - 0.88 8.3 8.9 1.1 8.0 6.2 1.1 1 0 0 1 1 1 0 Presenilin PcfK PF14058.1 CDI87950.1 - 2.2 8.4 25.9 0.079 13.1 5.9 2.0 2 0 0 2 2 2 0 PcfK-like protein UPF0233 PF06781.7 CDI87950.1 - 2.6 7.7 4.3 1.8 8.2 0.1 2.3 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0233) TMEM223 PF14640.1 CDI87950.1 - 2.7 7.9 5.8 2 8.3 0.5 2.1 1 1 0 2 2 2 0 Transmembrane protein 223 DUF1120 PF06551.7 CDI87950.1 - 4.1 7.7 6.1 5.2 7.3 3.9 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1120) SPT6_acidic PF14632.1 CDI87950.1 - 4.2 7.6 15.4 1.6 8.9 3.0 2.2 2 0 0 2 2 2 0 Acidic N-terminal SPT6 DUF912 PF06024.7 CDI87950.1 - 7.4 6.6 15.4 0.091 12.8 2.2 2.2 1 1 1 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Trp_oprn_chp PF09534.5 CDI87950.1 - 9.2 5.8 9.2 23 4.5 6.5 1.5 1 1 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Gastrin PF00918.12 CDI87951.1 - 0.0043 17.8 3.7 0.0048 17.6 2.5 1.1 1 0 0 1 1 1 1 Gastrin/cholecystokinin family FimP PF09766.4 CDI87951.1 - 0.0084 15.2 11.1 0.0092 15.0 7.7 1.0 1 0 0 1 1 1 1 Fms-interacting protein SpoIIIAH PF12685.2 CDI87951.1 - 0.017 14.6 7.6 0.017 14.5 5.3 1.1 1 0 0 1 1 1 0 SpoIIIAH-like protein FAM176 PF14851.1 CDI87951.1 - 0.018 14.6 5.2 0.023 14.3 3.6 1.2 1 0 0 1 1 1 0 FAM176 family DUF1510 PF07423.6 CDI87951.1 - 0.019 14.3 13.3 0.02 14.2 9.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Upf2 PF04050.9 CDI87951.1 - 0.029 14.1 17.1 0.032 13.9 11.9 1.1 1 0 0 1 1 1 0 Up-frameshift suppressor 2 Shisa PF13908.1 CDI87951.1 - 0.051 13.7 3.1 0.055 13.6 2.1 1.1 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator DUF4355 PF14265.1 CDI87951.1 - 0.066 13.1 18.3 0.072 13.0 12.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4355) YqfQ PF14181.1 CDI87951.1 - 0.097 12.7 11.9 0.11 12.5 8.3 1.1 1 0 0 1 1 1 0 YqfQ-like protein CobT PF06213.7 CDI87951.1 - 0.12 11.4 17.8 0.14 11.2 12.3 1.0 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF2514 PF10721.4 CDI87951.1 - 0.13 11.9 10.4 0.14 11.8 7.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) Suf PF05843.9 CDI87951.1 - 0.13 11.9 8.2 0.15 11.8 5.7 1.0 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF2360 PF10152.4 CDI87951.1 - 0.15 12.3 8.6 0.17 12.1 6.0 1.0 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) ERF PF04404.7 CDI87951.1 - 0.17 11.3 11.3 0.21 11.0 7.8 1.2 1 0 0 1 1 1 0 ERF superfamily Spt20 PF12090.3 CDI87951.1 - 0.21 10.9 4.6 0.26 10.5 3.2 1.3 1 0 0 1 1 1 0 Spt20 family AIF_C PF14721.1 CDI87951.1 - 0.25 11.5 5.4 0.29 11.3 3.8 1.2 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Peptidase_S49_N PF08496.5 CDI87951.1 - 0.26 11.0 3.8 0.28 10.9 2.6 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal CDC45 PF02724.9 CDI87951.1 - 0.38 8.7 16.3 0.42 8.5 11.3 1.0 1 0 0 1 1 1 0 CDC45-like protein SID-1_RNA_chan PF13965.1 CDI87951.1 - 0.4 8.7 4.3 0.42 8.7 3.0 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DUF1764 PF08576.5 CDI87951.1 - 0.43 11.3 10.7 0.47 11.2 7.4 1.1 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) zf-DHHC PF01529.15 CDI87951.1 - 0.45 9.8 1.8 0.46 9.8 1.3 1.2 1 0 0 1 1 1 0 DHHC palmitoyltransferase COPR5 PF15340.1 CDI87951.1 - 0.47 10.8 8.6 0.55 10.6 6.0 1.0 1 0 0 1 1 1 0 Cooperator of PRMT5 family RP-C_C PF11800.3 CDI87951.1 - 0.48 10.0 7.0 0.49 10.0 4.9 1.0 1 0 0 1 1 1 0 Replication protein C C-terminal region Band_3_cyto PF07565.8 CDI87951.1 - 0.58 9.6 5.3 0.57 9.6 3.7 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Tom37_C PF11801.3 CDI87951.1 - 0.62 9.9 8.8 0.71 9.7 6.1 1.0 1 0 0 1 1 1 0 Tom37 C-terminal domain TRAP_alpha PF03896.11 CDI87951.1 - 0.63 8.9 10.1 0.67 8.8 7.0 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit TLP-20 PF06088.6 CDI87951.1 - 0.64 9.6 7.5 0.77 9.4 5.2 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) CPSF100_C PF13299.1 CDI87951.1 - 0.71 10.0 7.8 0.8 9.8 5.4 1.1 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal DUF1980 PF09323.5 CDI87951.1 - 0.89 9.2 5.3 0.95 9.1 3.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) DUF789 PF05623.7 CDI87951.1 - 0.99 8.8 6.8 1 8.7 4.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF789) DUF788 PF05620.6 CDI87951.1 - 1 9.1 5.6 1.3 8.8 3.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF788) Nop14 PF04147.7 CDI87951.1 - 1.1 7.1 21.1 1.1 7.0 14.6 1.0 1 0 0 1 1 1 0 Nop14-like family SHR3_chaperone PF08229.6 CDI87951.1 - 1.1 8.1 7.5 1.1 8.1 5.2 1.2 1 0 0 1 1 1 0 ER membrane protein SH3 Raftlin PF15250.1 CDI87951.1 - 1.2 7.5 8.4 1.3 7.4 5.8 1.0 1 0 0 1 1 1 0 Raftlin Serinc PF03348.10 CDI87951.1 - 1.2 7.7 7.2 1.3 7.6 5.0 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) FemAB PF02388.11 CDI87951.1 - 1.2 7.7 8.0 1.3 7.5 5.6 1.1 1 0 0 1 1 1 0 FemAB family VID27 PF08553.5 CDI87951.1 - 1.2 7.2 14.1 1.4 7.0 9.7 1.0 1 0 0 1 1 1 0 VID27 cytoplasmic protein Tim54 PF11711.3 CDI87951.1 - 1.2 7.6 10.5 1.3 7.5 7.3 1.0 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Trypan_PARP PF05887.6 CDI87951.1 - 1.2 8.9 7.3 1.4 8.7 5.0 1.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DUF3260 PF11658.3 CDI87951.1 - 1.3 7.0 5.4 1.3 7.0 3.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3260) Spore_coat_CotO PF14153.1 CDI87951.1 - 1.3 8.4 17.7 1.5 8.2 12.3 1.1 1 0 0 1 1 1 0 Spore coat protein CotO SDA1 PF05285.7 CDI87951.1 - 1.5 8.0 18.5 1.7 7.8 12.9 1.0 1 0 0 1 1 1 0 SDA1 SprA-related PF12118.3 CDI87951.1 - 1.5 8.0 20.7 1.6 7.9 14.3 1.0 1 0 0 1 1 1 0 SprA-related family BNIP3 PF06553.7 CDI87951.1 - 1.6 8.0 8.4 1.7 7.9 5.8 1.1 1 0 0 1 1 1 0 BNIP3 DDRGK PF09756.4 CDI87951.1 - 1.7 8.0 16.4 1.9 7.8 11.3 1.1 1 0 0 1 1 1 0 DDRGK domain SCIMP PF15050.1 CDI87951.1 - 1.7 8.5 5.3 1.9 8.4 3.3 1.4 1 1 0 1 1 1 0 SCIMP protein DUF2201_N PF13203.1 CDI87951.1 - 1.8 7.6 10.9 1.9 7.5 7.6 1.0 1 0 0 1 1 1 0 Putative metallopeptidase domain Ebola_NP PF05505.7 CDI87951.1 - 1.8 6.5 10.3 1.8 6.4 7.1 1.0 1 0 0 1 1 1 0 Ebola nucleoprotein DUF3408 PF11888.3 CDI87951.1 - 2 8.3 10.6 2.3 8.1 7.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) EIIBC-GUT_N PF03612.9 CDI87951.1 - 2 8.0 6.4 2.4 7.7 4.5 1.3 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus HSP90 PF00183.13 CDI87951.1 - 2.2 6.5 11.7 2.3 6.5 8.1 1.0 1 0 0 1 1 1 0 Hsp90 protein XAP5 PF04921.9 CDI87951.1 - 2.3 7.7 11.9 2.7 7.4 8.3 1.0 1 0 0 1 1 1 0 XAP5, circadian clock regulator SAPS PF04499.10 CDI87951.1 - 2.3 6.7 12.0 2.6 6.5 8.3 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Sec62 PF03839.11 CDI87951.1 - 2.6 7.4 9.5 3 7.2 6.6 1.0 1 0 0 1 1 1 0 Translocation protein Sec62 Zip PF02535.17 CDI87951.1 - 3 6.7 5.4 3.5 6.5 3.8 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter Hid1 PF12722.2 CDI87951.1 - 3.5 5.1 10.3 3.8 5.0 7.1 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Glyco_transf_15 PF01793.11 CDI87951.1 - 3.6 6.4 7.4 3.8 6.3 5.1 1.0 1 0 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase FAM60A PF15396.1 CDI87951.1 - 3.6 7.2 6.1 4.1 7.1 4.2 1.1 1 0 0 1 1 1 0 Protein Family FAM60A Herpes_DNAp_acc PF04929.7 CDI87951.1 - 4 6.3 8.6 4.4 6.1 5.9 1.0 1 0 0 1 1 1 0 Herpes DNA replication accessory factor DDHD PF02862.12 CDI87951.1 - 4 7.1 12.1 4.7 6.9 8.4 1.1 1 0 0 1 1 1 0 DDHD domain ATHILA PF03078.10 CDI87951.1 - 4.1 5.8 9.0 4.1 5.8 6.3 1.0 1 0 0 1 1 1 0 ATHILA ORF-1 family Daxx PF03344.10 CDI87951.1 - 4.2 5.7 19.8 4.4 5.6 13.7 1.1 1 0 0 1 1 1 0 Daxx Family DUF3381 PF11861.3 CDI87951.1 - 4.2 6.8 16.1 4.9 6.6 11.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) DUF4175 PF13779.1 CDI87951.1 - 4.2 4.9 21.1 4.6 4.8 14.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Presenilin PF01080.12 CDI87951.1 - 4.3 6.0 6.9 4.4 6.0 4.8 1.1 1 0 0 1 1 1 0 Presenilin RRN3 PF05327.6 CDI87951.1 - 4.6 5.2 11.3 4.8 5.1 7.8 1.0 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Plasmodium_Vir PF05795.6 CDI87951.1 - 4.9 6.2 5.7 5.2 6.1 4.0 1.0 1 0 0 1 1 1 0 Plasmodium vivax Vir protein GOLD_2 PF13897.1 CDI87951.1 - 5.3 7.2 6.5 6.9 6.9 4.5 1.3 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking Gti1_Pac2 PF09729.4 CDI87951.1 - 5.3 6.8 7.3 6.2 6.6 5.0 1.1 1 0 0 1 1 1 0 Gti1/Pac2 family Prog_receptor PF02161.10 CDI87951.1 - 5.8 5.6 12.2 6.2 5.5 8.5 1.1 1 0 0 1 1 1 0 Progesterone receptor DHHW PF14286.1 CDI87951.1 - 6.5 5.9 10.8 7.3 5.7 7.5 1.0 1 0 0 1 1 1 0 DHHW protein TEX19 PF15553.1 CDI87951.1 - 7 6.5 9.8 8.1 6.2 6.8 1.1 1 0 0 1 1 1 0 Testis-expressed protein 19 NPR3 PF03666.8 CDI87951.1 - 7.1 5.0 9.2 7.6 4.9 6.4 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 RR_TM4-6 PF06459.7 CDI87951.1 - 7.9 6.2 15.8 8.8 6.1 11.0 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SpoVR PF04293.8 CDI87951.1 - 8.8 4.5 10.0 9.6 4.4 7.0 1.0 1 0 0 1 1 1 0 SpoVR like protein Paramyxo_ncap PF00973.14 CDI87951.1 - 9 4.8 7.8 9.7 4.7 5.4 1.0 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein DUF4557 PF15101.1 CDI87951.1 - 9.3 6.0 11.7 10 5.9 8.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) ATP-synt_E PF05680.7 CDI87951.1 - 10 6.1 11.4 13 5.8 7.9 1.3 1 0 0 1 1 1 0 ATP synthase E chain ROS_MUCR PF05443.6 CDI87952.1 - 0.028 14.1 0.7 0.028 14.1 0.5 2.0 2 0 0 2 2 2 0 ROS/MUCR transcriptional regulator protein BAF1_ABF1 PF04684.8 CDI87953.1 - 0.00044 19.2 13.7 0.00044 19.2 9.5 4.4 3 1 2 5 5 5 1 BAF1 / ABF1 chromatin reorganising factor Adeno_PIX PF03955.9 CDI87953.1 - 0.013 16.0 6.2 0.013 16.0 4.3 4.0 3 1 1 4 4 4 0 Adenovirus hexon-associated protein (IX) DUF485 PF04341.7 CDI87953.1 - 0.022 14.4 0.3 0.022 14.4 0.2 2.4 3 0 0 3 3 3 0 Protein of unknown function, DUF485 RGCC PF15151.1 CDI87953.1 - 0.072 13.5 2.0 0.16 12.3 1.4 1.6 1 0 0 1 1 1 0 Response gene to complement 32 protein family WLM PF08325.5 CDI87953.1 - 3.1 7.6 8.9 7.7 6.3 6.1 1.6 1 0 0 1 1 1 0 WLM domain DUF3306 PF11748.3 CDI87954.1 - 0.18 12.4 1.2 0.24 12.0 0.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3306) FdhE PF04216.7 CDI87955.1 - 0.66 9.6 9.9 0.8 9.3 6.9 1.1 1 0 0 1 1 1 0 Protein involved in formate dehydrogenase formation Med3 PF11593.3 CDI87955.1 - 5.9 6.0 20.2 7.7 5.6 14.0 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal WD40 PF00400.27 CDI87956.1 - 3.2e-10 39.4 6.9 0.0004 20.1 0.5 3.7 3 0 0 3 3 3 3 WD domain, G-beta repeat TPR_14 PF13428.1 CDI87956.1 - 2.4 9.0 11.9 26 5.8 0.8 5.3 4 0 0 4 4 4 0 Tetratricopeptide repeat Ifi-6-16 PF06140.8 CDI87957.1 - 0.01 15.6 2.7 0.01 15.6 1.9 2.6 3 0 0 3 3 3 0 Interferon-induced 6-16 family NTP_transf_3 PF12804.2 CDI87957.1 - 0.89 9.6 7.2 0.085 12.9 1.7 1.6 2 0 0 2 2 2 0 MobA-like NTP transferase domain PAT1 PF09770.4 CDI87957.1 - 3.6 5.7 11.9 4.5 5.3 8.3 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 IncA PF04156.9 CDI87958.1 - 0.01 15.4 2.1 0.01 15.4 1.4 2.8 3 0 0 3 3 3 1 IncA protein Med15 PF09606.5 CDI87959.1 - 0.024 12.8 18.7 0.029 12.6 12.9 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal CDK2AP PF09806.4 CDI87959.1 - 0.062 13.5 9.1 0.076 13.2 6.3 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein IL2 PF00715.12 CDI87959.1 - 0.11 12.1 0.8 0.19 11.4 0.5 1.3 1 0 0 1 1 1 0 Interleukin 2 INO80_Ies4 PF08193.6 CDI87959.1 - 0.26 11.1 4.5 0.32 10.8 3.2 1.1 1 0 0 1 1 1 0 INO80 complex subunit Ies4 UPF0565 PF10561.4 CDI87959.1 - 0.3 9.9 4.7 0.38 9.6 3.3 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0565 DUF4367 PF14285.1 CDI87959.1 - 0.56 9.5 3.0 0.9 8.8 2.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4367) DUF3123 PF11321.3 CDI87959.1 - 6.6 7.0 9.7 11 6.3 6.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3123) TFIIA PF03153.8 CDI87959.1 - 8.3 6.1 17.0 11 5.7 11.8 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Spore_coat_CotO PF14153.1 CDI87961.1 - 3.8 6.9 37.2 4.1 6.8 25.8 1.1 1 0 0 1 1 1 0 Spore coat protein CotO Ldh_1_N PF00056.18 CDI87962.1 - 2.2e-14 53.4 1.4 2.7e-14 53.1 1.0 1.0 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 CDI87962.1 - 0.032 12.9 0.2 0.036 12.7 0.1 1.0 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family F420_oxidored PF03807.12 CDI87962.1 - 0.035 14.5 1.6 0.058 13.8 1.1 1.4 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent RskA PF10099.4 CDI87963.1 - 5.5e-05 22.9 18.0 7.3e-05 22.5 12.5 1.1 1 0 0 1 1 1 1 Anti-sigma-K factor rskA DUF4367 PF14285.1 CDI87963.1 - 0.0021 17.3 1.4 0.0032 16.7 1.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4367) Shadoo PF14999.1 CDI87963.1 - 0.0022 17.8 0.7 0.0027 17.5 0.5 1.2 1 0 0 1 1 1 1 Shadow of prion protein, neuroprotective Apc1 PF12859.2 CDI87963.1 - 0.0061 16.7 5.6 0.0061 16.7 3.9 2.0 1 1 1 2 2 2 1 Anaphase-promoting complex subunit 1 DUF4366 PF14283.1 CDI87963.1 - 0.0067 15.8 4.7 0.0089 15.4 3.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4366) Trp_oprn_chp PF09534.5 CDI87963.1 - 0.0074 15.9 10.3 0.0086 15.7 7.1 1.1 1 0 0 1 1 1 1 Tryptophan-associated transmembrane protein (Trp_oprn_chp) AAA_11 PF13086.1 CDI87963.1 - 0.015 14.8 12.5 0.019 14.5 8.7 1.0 1 0 0 1 1 1 0 AAA domain DUF3357 PF11837.3 CDI87963.1 - 0.041 13.7 2.7 0.11 12.4 1.9 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF3357) Ctr PF04145.10 CDI87963.1 - 0.043 13.8 13.2 0.25 11.4 5.1 2.0 1 1 1 2 2 2 0 Ctr copper transporter family PEX11 PF05648.9 CDI87963.1 - 0.053 12.7 12.6 0.56 9.4 4.1 2.0 1 1 1 2 2 2 0 Peroxisomal biogenesis factor 11 (PEX11) MRP-S31 PF15433.1 CDI87963.1 - 0.12 11.8 19.4 0.15 11.4 13.4 1.1 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 Rtf2 PF04641.7 CDI87963.1 - 0.14 11.3 13.2 0.17 11.0 9.1 1.2 1 0 0 1 1 1 0 Rtf2 RING-finger RIB43A PF05914.7 CDI87963.1 - 0.15 10.7 35.5 0.18 10.3 24.6 1.1 1 0 0 1 1 1 0 RIB43A OPT PF03169.10 CDI87963.1 - 0.21 10.0 2.6 0.24 9.7 1.8 1.0 1 0 0 1 1 1 0 OPT oligopeptide transporter protein DivIC PF04977.10 CDI87963.1 - 0.25 10.8 25.9 1.3 8.5 10.0 2.2 2 0 0 2 2 2 0 Septum formation initiator DUF3449 PF11931.3 CDI87963.1 - 0.27 10.7 10.4 0.4 10.1 7.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3449) DUF4386 PF14329.1 CDI87963.1 - 0.31 10.4 4.1 0.42 10.0 2.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4386) DUF4179 PF13786.1 CDI87963.1 - 0.38 10.9 2.5 0.38 10.9 1.1 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4179) APC_CDC26 PF10471.4 CDI87963.1 - 0.39 11.4 37.3 2.6 8.8 12.3 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit 1 DUF4048 PF13257.1 CDI87963.1 - 0.45 10.1 15.6 0.56 9.8 10.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4048) DUF4647 PF15504.1 CDI87963.1 - 0.51 9.1 21.9 0.62 8.8 15.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4647) RdRP_3 PF00998.18 CDI87963.1 - 0.59 8.5 8.0 0.67 8.3 5.6 1.1 1 0 0 1 1 1 0 Viral RNA dependent RNA polymerase TFIIA PF03153.8 CDI87963.1 - 0.66 9.8 31.8 0.79 9.5 22.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit FHIPEP PF00771.15 CDI87963.1 - 0.78 7.9 14.5 1.2 7.3 10.1 1.3 1 1 0 1 1 1 0 FHIPEP family DUF4598 PF15370.1 CDI87963.1 - 1.2 9.4 9.8 0.36 11.1 2.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4598) EphA2_TM PF14575.1 CDI87963.1 - 1.5 9.2 13.7 0.96 9.8 1.7 2.2 1 1 1 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Peptidase_S21 PF00716.12 CDI87963.1 - 1.7 7.8 12.3 2.1 7.6 8.6 1.1 1 0 0 1 1 1 0 Assemblin (Peptidase family S21) Peptidase_M56 PF05569.6 CDI87963.1 - 2 7.3 6.4 2.4 7.0 4.5 1.1 1 0 0 1 1 1 0 BlaR1 peptidase M56 DUF4050 PF13259.1 CDI87963.1 - 2 8.3 15.3 0.27 11.1 2.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4050) FAM60A PF15396.1 CDI87963.1 - 2.2 8.0 12.7 2.9 7.5 8.8 1.2 1 0 0 1 1 1 0 Protein Family FAM60A Mucin PF01456.12 CDI87963.1 - 2.2 8.0 10.6 0.042 13.6 1.6 1.9 2 0 0 2 2 2 0 Mucin-like glycoprotein BTV_NS2 PF04514.7 CDI87963.1 - 2.7 6.7 13.0 3.2 6.5 9.0 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 MDFI PF15316.1 CDI87963.1 - 2.8 7.8 10.6 3.9 7.4 7.4 1.3 1 0 0 1 1 1 0 MyoD family inhibitor Conotoxin PF02950.12 CDI87963.1 - 2.9 8.7 11.8 4.1 8.2 2.9 2.4 2 0 0 2 2 2 0 Conotoxin WBS_methylT PF12589.3 CDI87963.1 - 3.2 8.2 13.2 9 6.8 0.4 2.1 2 0 0 2 2 2 0 Methyltransferase involved in Williams-Beuren syndrome SID-1_RNA_chan PF13965.1 CDI87963.1 - 3.3 5.7 7.8 4.1 5.4 5.4 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 AAA_28 PF13521.1 CDI87963.1 - 3.3 7.6 12.4 6 6.8 8.6 1.3 1 1 0 1 1 1 0 AAA domain FLO_LFY PF01698.11 CDI87963.1 - 3.4 6.4 16.1 4.1 6.1 11.2 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein DUF1644 PF07800.7 CDI87963.1 - 3.7 7.3 9.4 8.9 6.1 1.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1644) CD20 PF04103.10 CDI87963.1 - 3.8 7.4 11.2 0.17 11.7 0.9 2.1 1 1 1 2 2 2 0 CD20-like family Rxt3 PF08642.5 CDI87963.1 - 4.6 7.5 13.1 1.3 9.2 2.4 2.1 1 1 0 2 2 2 0 Histone deacetylation protein Rxt3 E7 PF00527.13 CDI87963.1 - 5.1 7.3 13.0 9.3 6.4 0.8 2.2 2 0 0 2 2 2 0 E7 protein, Early protein Draxin PF15550.1 CDI87963.1 - 5.2 6.6 16.7 7.3 6.1 11.6 1.2 1 0 0 1 1 1 0 Draxin PAT1 PF09770.4 CDI87963.1 - 5.4 5.1 42.8 6.3 4.9 29.7 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Med19 PF10278.4 CDI87963.1 - 5.6 6.6 14.1 1.6 8.3 3.1 2.0 1 1 1 2 2 2 0 Mediator of RNA pol II transcription subunit 19 DUF543 PF04418.7 CDI87963.1 - 5.8 6.9 5.6 25 4.9 1.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF543) Ribosomal_60s PF00428.14 CDI87963.1 - 5.8 7.3 12.2 12 6.3 8.5 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein Neur_chan_memb PF02932.11 CDI87963.1 - 6.1 6.6 10.1 8.3 6.2 7.0 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Trypan_glycop_C PF10659.4 CDI87963.1 - 6.7 7.0 11.3 4.1 7.7 1.8 2.3 2 0 0 2 2 2 0 Trypanosome variant surface glycoprotein C-terminal domain zf-DHHC PF01529.15 CDI87963.1 - 8.5 5.7 11.0 2.7 7.3 2.4 2.1 2 0 0 2 2 2 0 DHHC palmitoyltransferase FxsA PF04186.8 CDI87963.1 - 9.2 5.9 15.5 9.1 5.9 1.9 2.1 1 1 1 2 2 2 0 FxsA cytoplasmic membrane protein Glyco_hydro_3_C PF01915.17 CDI87963.1 - 9.4 5.6 10.0 12 5.3 6.9 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 3 C-terminal domain Peptidase_S64 PF08192.6 CDI87963.1 - 9.8 4.3 13.4 12 4.1 9.3 1.1 1 0 0 1 1 1 0 Peptidase family S64 PAT1 PF09770.4 CDI87964.1 - 0.00081 17.7 33.4 0.00087 17.6 23.2 1.1 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 MRP-S31 PF15433.1 CDI87964.1 - 0.0039 16.6 17.0 0.006 16.0 11.8 1.2 1 0 0 1 1 1 1 Mitochondrial 28S ribosomal protein S31 Herpes_BLLF1 PF05109.8 CDI87964.1 - 0.0092 14.0 12.2 0.011 13.7 8.4 1.2 1 0 0 1 1 1 1 Herpes virus major outer envelope glycoprotein (BLLF1) Adeno_PIX PF03955.9 CDI87964.1 - 0.022 15.2 4.8 0.022 15.2 3.3 4.0 1 1 3 4 4 3 0 Adenovirus hexon-associated protein (IX) DUF3373 PF11853.3 CDI87964.1 - 0.041 12.4 10.9 0.07 11.6 7.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) DHHW PF14286.1 CDI87964.1 - 0.067 12.5 5.4 0.09 12.0 3.8 1.2 1 0 0 1 1 1 0 DHHW protein Calici_coat_C PF08435.6 CDI87964.1 - 0.32 10.2 8.5 0.49 9.6 5.9 1.3 1 0 0 1 1 1 0 Calicivirus coat protein C-terminal Allexi_40kDa PF05549.6 CDI87964.1 - 0.46 9.7 10.5 0.68 9.1 7.3 1.2 1 0 0 1 1 1 0 Allexivirus 40kDa protein SPX PF03105.14 CDI87964.1 - 0.71 9.5 13.9 0.99 9.1 9.6 1.2 1 0 0 1 1 1 0 SPX domain DDHD PF02862.12 CDI87964.1 - 0.81 9.4 13.2 1.3 8.8 9.2 1.2 1 0 0 1 1 1 0 DDHD domain eIF-3_zeta PF05091.7 CDI87964.1 - 1.3 7.6 14.8 1.6 7.2 10.3 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Ycf1 PF05758.7 CDI87964.1 - 1.9 6.1 10.3 2.3 5.8 7.2 1.0 1 0 0 1 1 1 0 Ycf1 DUF3102 PF11300.3 CDI87964.1 - 3.5 7.6 14.4 0.86 9.6 0.7 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3102) Herpes_UL87 PF03043.9 CDI87964.1 - 3.6 5.8 8.3 4.6 5.4 5.7 1.1 1 0 0 1 1 1 0 Herpesvirus UL87 family FAM60A PF15396.1 CDI87964.1 - 4 7.1 12.3 5.9 6.5 8.5 1.3 1 0 0 1 1 1 0 Protein Family FAM60A Baculo_PP31 PF05311.6 CDI87964.1 - 5.4 6.2 11.5 8.6 5.5 8.0 1.3 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) Suf PF05843.9 CDI87964.1 - 6.8 6.3 31.6 0.18 11.4 6.8 2.1 1 1 1 2 2 2 0 Suppressor of forked protein (Suf) Presenilin PF01080.12 CDI87964.1 - 7.3 5.3 12.8 14 4.3 8.9 1.4 1 0 0 1 1 1 0 Presenilin Het-C PF07217.6 CDI87964.1 - 9.1 4.3 12.8 12 3.9 8.9 1.1 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C UPF0565 PF10561.4 CDI87965.1 - 0.13 11.1 4.5 0.33 9.8 1.9 2.0 1 1 1 2 2 2 0 Uncharacterised protein family UPF0565 Med15 PF09606.5 CDI87966.1 - 0.027 12.6 62.3 0.03 12.5 43.2 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF1510 PF07423.6 CDI87966.1 - 0.063 12.6 20.1 0.079 12.3 13.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Choline_transpo PF04515.7 CDI87966.1 - 0.066 11.9 0.0 0.078 11.7 0.0 1.2 1 0 0 1 1 1 0 Plasma-membrane choline transporter SelP_N PF04592.9 CDI87966.1 - 0.072 12.4 16.9 0.078 12.3 11.7 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region FHIPEP PF00771.15 CDI87966.1 - 0.32 9.2 14.1 0.39 8.9 9.8 1.2 1 0 0 1 1 1 0 FHIPEP family DUF1980 PF09323.5 CDI87966.1 - 0.41 10.3 12.4 0.55 9.9 8.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) Paf1 PF03985.8 CDI87966.1 - 0.54 8.9 21.8 0.52 8.9 15.1 1.1 1 0 0 1 1 1 0 Paf1 ABC2_membrane_2 PF12679.2 CDI87966.1 - 0.56 9.0 4.8 1.2 7.9 3.3 1.6 1 1 0 1 1 1 0 ABC-2 family transporter protein Folate_carrier PF01770.13 CDI87966.1 - 0.76 8.2 11.7 0.93 7.9 8.1 1.1 1 0 0 1 1 1 0 Reduced folate carrier Band_3_cyto PF07565.8 CDI87966.1 - 0.95 8.9 18.2 1.2 8.6 12.6 1.3 1 0 0 1 1 1 0 Band 3 cytoplasmic domain SID-1_RNA_chan PF13965.1 CDI87966.1 - 1.4 7.0 10.9 1.4 7.0 7.5 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DUF4179 PF13786.1 CDI87966.1 - 1.4 9.1 5.7 2.5 8.3 3.9 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4179) SprA-related PF12118.3 CDI87966.1 - 1.6 7.9 54.1 2 7.6 37.5 1.1 1 0 0 1 1 1 0 SprA-related family Bac_luciferase PF00296.15 CDI87966.1 - 1.6 7.7 12.4 2.4 7.2 8.6 1.3 1 1 0 1 1 1 0 Luciferase-like monooxygenase MgsA_C PF12002.3 CDI87966.1 - 1.6 8.3 13.3 2 8.0 9.2 1.2 1 0 0 1 1 1 0 MgsA AAA+ ATPase C terminal DDHD PF02862.12 CDI87966.1 - 1.8 8.3 22.4 2.2 8.0 15.5 1.0 1 0 0 1 1 1 0 DDHD domain FLO_LFY PF01698.11 CDI87966.1 - 2 7.1 21.5 2.4 6.9 14.9 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein Herpes_glycop PF01528.11 CDI87966.1 - 2.1 6.9 7.6 3 6.4 5.3 1.3 1 0 0 1 1 1 0 Herpesvirus glycoprotein M DUF4446 PF14584.1 CDI87966.1 - 2.1 8.1 9.8 2.9 7.7 6.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) Mem_trans PF03547.13 CDI87966.1 - 2.8 6.1 7.4 3 6.0 5.1 1.2 1 0 0 1 1 1 0 Membrane transport protein Abhydrolase_9_N PF15420.1 CDI87966.1 - 2.9 7.5 8.5 0.17 11.6 2.4 1.5 1 1 0 1 1 1 0 Alpha/beta-hydrolase family N-terminus SDF PF00375.13 CDI87966.1 - 3.1 6.4 7.3 6.1 5.4 5.1 1.5 1 1 0 1 1 1 0 Sodium:dicarboxylate symporter family Herpes_DNAp_acc PF04929.7 CDI87966.1 - 3.2 6.6 18.9 3.3 6.5 13.1 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor FAP PF07174.6 CDI87966.1 - 3.2 6.9 9.7 3.7 6.7 6.8 1.0 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) DUF2215 PF10225.4 CDI87966.1 - 3.5 7.0 15.5 4.1 6.7 10.7 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) PAT1 PF09770.4 CDI87966.1 - 3.6 5.7 53.8 3.7 5.6 37.3 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 CDC45 PF02724.9 CDI87966.1 - 4 5.3 18.4 3.9 5.4 12.8 1.1 1 0 0 1 1 1 0 CDC45-like protein Peptidase_S49_N PF08496.5 CDI87966.1 - 4.1 7.1 18.2 5.9 6.6 12.6 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF2370 PF10176.4 CDI87966.1 - 4.2 6.6 13.8 4.8 6.4 9.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) DUF4367 PF14285.1 CDI87966.1 - 4.4 6.5 7.9 5.6 6.2 5.5 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4367) TCP PF03634.8 CDI87966.1 - 4.8 7.5 28.1 5.9 7.2 19.4 1.2 1 0 0 1 1 1 0 TCP family transcription factor PPP4R2 PF09184.6 CDI87966.1 - 5 6.5 16.7 5.3 6.4 11.6 1.0 1 0 0 1 1 1 0 PPP4R2 DUF342 PF03961.8 CDI87966.1 - 5.5 5.2 14.1 5.6 5.2 9.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) SpaB_C PF14028.1 CDI87966.1 - 5.8 6.3 14.5 6.9 6.1 10.0 1.1 1 0 0 1 1 1 0 SpaB C-terminal domain CD20 PF04103.10 CDI87966.1 - 5.9 6.8 11.7 31 4.4 8.1 1.9 1 1 0 1 1 1 0 CD20-like family Raftlin PF15250.1 CDI87966.1 - 6.2 5.2 22.3 6.4 5.1 15.4 1.0 1 0 0 1 1 1 0 Raftlin Rtf2 PF04641.7 CDI87966.1 - 7 5.7 22.4 9.1 5.3 15.5 1.3 1 0 0 1 1 1 0 Rtf2 RING-finger Hid1 PF12722.2 CDI87966.1 - 7.4 4.1 21.7 7.2 4.1 15.1 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SpoVR PF04293.8 CDI87966.1 - 8.4 4.6 20.7 8.2 4.6 14.4 1.1 1 0 0 1 1 1 0 SpoVR like protein Peptidase_S15 PF02129.13 CDI87966.1 - 8.5 5.7 22.3 10 5.4 15.4 1.0 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) eIF-3_zeta PF05091.7 CDI87966.1 - 8.7 4.8 27.4 8.7 4.8 19.0 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF3260 PF11658.3 CDI87966.1 - 9.1 4.2 19.5 9.6 4.2 13.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3260) Peptidase_U57 PF05582.7 CDI87966.1 - 9.8 5.0 16.0 10 4.9 11.1 1.1 1 0 0 1 1 1 0 YabG peptidase U57 Spc7_N PF15402.1 CDI87966.1 - 9.8 4.0 27.8 11 3.8 19.3 1.1 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 GAGA_bind PF06217.7 CDI87967.1 - 0.36 10.7 21.8 0.46 10.4 15.1 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family Bac_GDH PF05088.7 CDI87967.1 - 1.7 5.9 21.1 2 5.6 14.6 1.0 1 0 0 1 1 1 0 Bacterial NAD-glutamate dehydrogenase DUF2317 PF10079.4 CDI87967.1 - 4.3 5.8 33.5 6.4 5.2 23.2 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2317) Med8 PF10232.4 CDI87969.1 - 0.91 8.9 8.5 1.1 8.7 5.9 1.1 1 0 0 1 1 1 0 Mediator of RNA polymerase II transcription complex subunit 8 DUF1510 PF07423.6 CDI87970.1 - 0.00036 19.9 14.0 0.00043 19.7 9.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) Conotoxin PF02950.12 CDI87970.1 - 0.0015 19.3 4.6 0.0015 19.3 3.2 2.3 1 1 1 2 2 1 1 Conotoxin CDC45 PF02724.9 CDI87970.1 - 0.0049 14.9 6.7 0.0053 14.8 4.6 1.1 1 0 0 1 1 1 1 CDC45-like protein Herpes_env PF01673.13 CDI87970.1 - 0.011 14.3 11.5 0.012 14.2 7.9 1.1 1 0 0 1 1 1 0 Herpesvirus putative major envelope glycoprotein DUF1183 PF06682.7 CDI87970.1 - 0.013 15.0 7.4 0.016 14.7 5.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) Zip PF02535.17 CDI87970.1 - 0.034 13.1 0.5 0.039 12.9 0.3 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter DUF1180 PF06679.7 CDI87970.1 - 0.042 13.7 2.2 0.072 12.9 1.5 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1180) PAT1 PF09770.4 CDI87970.1 - 0.051 11.8 48.0 0.058 11.6 33.2 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF3807 PF12720.2 CDI87970.1 - 0.054 13.6 18.1 0.068 13.3 12.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) DUF966 PF06136.8 CDI87970.1 - 0.069 12.5 15.2 0.079 12.3 10.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Neur_chan_memb PF02932.11 CDI87970.1 - 0.093 12.6 12.3 0.11 12.3 8.5 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region FAM60A PF15396.1 CDI87970.1 - 0.11 12.2 11.9 0.13 12.0 8.2 1.2 1 0 0 1 1 1 0 Protein Family FAM60A Ycf1 PF05758.7 CDI87970.1 - 0.13 9.9 17.1 0.15 9.7 11.9 1.0 1 0 0 1 1 1 0 Ycf1 Bul1_N PF04425.7 CDI87970.1 - 0.16 10.5 14.7 0.18 10.3 10.2 1.0 1 0 0 1 1 1 0 Bul1 N terminus SpoIIIAH PF12685.2 CDI87970.1 - 0.21 11.0 17.0 0.52 9.7 11.8 1.6 1 1 0 1 1 1 0 SpoIIIAH-like protein Sarcoglycan_2 PF05510.8 CDI87970.1 - 0.22 9.7 9.5 0.3 9.3 6.6 1.2 1 0 0 1 1 1 0 Sarcoglycan alpha/epsilon DUF2201_N PF13203.1 CDI87970.1 - 0.25 10.5 18.5 0.28 10.2 12.8 1.0 1 0 0 1 1 1 0 Putative metallopeptidase domain DUF605 PF04652.11 CDI87970.1 - 0.3 10.4 23.6 0.37 10.1 16.4 1.1 1 0 0 1 1 1 0 Vta1 like ETRAMP PF09716.5 CDI87970.1 - 0.32 10.9 6.8 1.4 8.9 3.3 2.6 1 1 1 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) SAGA-Tad1 PF12767.2 CDI87970.1 - 0.33 10.5 21.0 0.42 10.2 14.6 1.2 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit TFIIA PF03153.8 CDI87970.1 - 0.37 10.6 35.1 0.44 10.3 24.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Macoilin PF09726.4 CDI87970.1 - 0.37 9.0 17.9 0.43 8.8 12.4 1.0 1 0 0 1 1 1 0 Transmembrane protein DUF3708 PF12501.3 CDI87970.1 - 0.46 10.2 9.7 0.57 10.0 6.8 1.1 1 0 0 1 1 1 0 Phosphate ATP-binding cassette transporter Ctr PF04145.10 CDI87970.1 - 0.57 10.2 15.4 83 3.2 10.7 2.2 1 1 0 1 1 1 0 Ctr copper transporter family Hid1 PF12722.2 CDI87970.1 - 0.61 7.6 16.4 0.75 7.3 11.4 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein GAGA_bind PF06217.7 CDI87970.1 - 0.79 9.6 16.8 0.86 9.5 11.6 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family MRP-S31 PF15433.1 CDI87970.1 - 0.82 9.0 19.9 1.2 8.5 13.8 1.2 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 Herpes_UL87 PF03043.9 CDI87970.1 - 0.92 7.8 10.3 1 7.6 7.1 1.0 1 0 0 1 1 1 0 Herpesvirus UL87 family Herpes_DNAp_acc PF04929.7 CDI87970.1 - 1.2 8.0 15.5 1.5 7.7 10.8 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor HCO3_cotransp PF00955.16 CDI87970.1 - 1.3 7.6 5.8 1.5 7.4 4.0 1.2 1 0 0 1 1 1 0 HCO3- transporter family SID-1_RNA_chan PF13965.1 CDI87970.1 - 1.3 7.1 12.5 1.6 6.8 8.6 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 AvrE PF11725.3 CDI87970.1 - 1.3 5.9 20.3 1.4 5.8 14.0 1.0 1 0 0 1 1 1 0 Pathogenicity factor OAD_gamma PF04277.8 CDI87970.1 - 1.5 9.2 9.9 2.8 8.3 0.1 2.5 1 1 1 2 2 2 0 Oxaloacetate decarboxylase, gamma chain Fig1 PF12351.3 CDI87970.1 - 1.6 8.6 5.9 2.6 7.8 2.9 1.9 2 0 0 2 2 2 0 Ca2+ regulator and membrane fusion protein Fig1 DUF3357 PF11837.3 CDI87970.1 - 1.7 8.5 12.2 0.35 10.7 0.3 2.9 1 1 2 3 3 3 0 Domain of unknown function (DUF3357) FLO_LFY PF01698.11 CDI87970.1 - 1.8 7.3 14.8 2.1 7.1 10.2 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein DHHW PF14286.1 CDI87970.1 - 2.7 7.2 12.0 4.2 6.5 8.3 1.4 1 0 0 1 1 1 0 DHHW protein MscS_TM PF12794.2 CDI87970.1 - 3.7 6.0 15.3 5.2 5.5 0.2 2.2 2 0 0 2 2 2 0 Mechanosensitive ion channel inner membrane domain 1 DUF2782 PF11191.3 CDI87970.1 - 3.7 7.5 19.3 0.76 9.7 2.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2782) DUF2269 PF10027.4 CDI87970.1 - 4 7.2 7.8 12 5.6 0.2 2.4 2 1 0 2 2 2 0 Predicted integral membrane protein (DUF2269) Membralin PF09746.4 CDI87970.1 - 4.2 6.3 8.9 5 6.0 6.1 1.2 1 0 0 1 1 1 0 Tumour-associated protein Mucin PF01456.12 CDI87970.1 - 4.3 7.0 10.8 2.2 8.0 4.9 1.9 2 0 0 2 2 2 0 Mucin-like glycoprotein DUF4259 PF14078.1 CDI87970.1 - 4.8 7.6 10.4 1.5 9.3 4.3 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4259) FAM176 PF14851.1 CDI87970.1 - 5.5 6.6 16.6 8.5 6.0 1.1 2.2 1 1 1 2 2 2 0 FAM176 family DSPn PF14671.1 CDI87970.1 - 5.9 6.8 12.4 0.16 11.9 0.4 2.2 1 1 1 2 2 2 0 Dual specificity protein phosphatase, N-terminal half Presenilin PF01080.12 CDI87970.1 - 6.5 5.4 12.5 8.3 5.1 8.6 1.2 1 0 0 1 1 1 0 Presenilin eIF-3_zeta PF05091.7 CDI87970.1 - 8.8 4.8 20.6 13 4.2 14.3 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF3959 PF13105.1 CDI87970.1 - 9.3 5.4 11.1 14 4.9 7.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3959) IncA PF04156.9 CDI87971.1 - 0.0022 17.6 5.9 0.0024 17.4 4.1 1.1 1 0 0 1 1 1 1 IncA protein FimP PF09766.4 CDI87971.1 - 0.037 13.0 6.6 0.035 13.1 4.6 1.0 1 0 0 1 1 1 0 Fms-interacting protein RAB3GAP2_N PF14655.1 CDI87971.1 - 0.14 11.1 5.3 0.15 10.9 3.7 1.1 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus CPSF100_C PF13299.1 CDI87971.1 - 0.23 11.6 2.1 0.26 11.4 1.4 1.0 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal FHIPEP PF00771.15 CDI87971.1 - 0.28 9.4 3.6 0.28 9.4 2.5 1.0 1 0 0 1 1 1 0 FHIPEP family Spt20 PF12090.3 CDI87971.1 - 0.31 10.3 6.8 0.27 10.5 4.7 1.1 1 0 0 1 1 1 0 Spt20 family DUF3682 PF12446.3 CDI87971.1 - 0.4 10.9 15.4 0.54 10.5 10.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) DivIC PF04977.10 CDI87971.1 - 0.49 9.9 7.5 0.68 9.4 5.2 1.2 1 0 0 1 1 1 0 Septum formation initiator Serinc PF03348.10 CDI87971.1 - 0.8 8.3 2.5 0.72 8.5 1.7 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) Suf PF05843.9 CDI87971.1 - 1.2 8.8 9.5 1.2 8.7 6.6 1.0 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF4557 PF15101.1 CDI87971.1 - 1.3 8.8 9.8 1.3 8.8 6.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) Med15 PF09606.5 CDI87971.1 - 2.2 6.3 28.0 2.4 6.2 19.4 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal RskA PF10099.4 CDI87971.1 - 2.6 7.7 16.2 3.8 7.2 11.2 1.3 1 1 0 1 1 1 0 Anti-sigma-K factor rskA PAT1 PF09770.4 CDI87971.1 - 4.2 5.4 19.2 3.8 5.6 13.3 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF788 PF05620.6 CDI87971.1 - 4.3 7.1 5.1 4.6 7.0 3.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF788) UPF0560 PF10577.4 CDI87971.1 - 7.7 4.6 10.4 6.7 4.8 7.2 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 TFIIA PF03153.8 CDI87971.1 - 8.8 6.1 19.4 9.2 6.0 13.4 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CAF-1_p150 PF11600.3 CDI87972.1 - 0.028 13.7 11.3 0.039 13.3 7.8 1.3 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Zip PF02535.17 CDI87972.1 - 0.35 9.8 2.7 0.4 9.6 1.9 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Secretin_N_2 PF07655.8 CDI87972.1 - 0.43 10.9 13.9 0.11 12.8 5.1 2.2 2 0 0 2 2 2 0 Secretin N-terminal domain Suf PF05843.9 CDI87972.1 - 0.58 9.8 13.3 0.77 9.4 9.2 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) FAM176 PF14851.1 CDI87972.1 - 1.3 8.7 5.7 8.2 6.0 1.5 2.1 2 0 0 2 2 2 0 FAM176 family DUF2638 PF10937.3 CDI87972.1 - 4.5 8.3 8.0 0.48 11.4 2.2 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2638) Apc15p PF05841.6 CDI87972.1 - 4.6 8.0 21.8 2.7 8.7 3.7 2.2 2 0 0 2 2 2 0 Apc15p protein Conotoxin PF02950.12 CDI87972.1 - 5.5 7.8 9.9 9.9 7.0 2.9 2.4 2 0 0 2 2 2 0 Conotoxin Inp1 PF12634.2 CDI87972.1 - 8.1 6.1 12.6 0.27 10.8 1.6 2.1 2 0 0 2 2 2 0 Inheritance of peroxisomes protein 1 AF-4 PF05110.8 CDI87973.1 - 0.011 13.6 12.5 0.013 13.4 8.7 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Ribosomal_60s PF00428.14 CDI87973.1 - 0.02 15.2 7.0 0.02 15.2 4.8 2.2 2 0 0 2 2 2 0 60s Acidic ribosomal protein Sporozoite_P67 PF05642.6 CDI87973.1 - 0.07 10.9 3.2 0.082 10.7 2.2 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF2217 PF10265.4 CDI87973.1 - 0.14 10.8 3.1 0.18 10.4 2.1 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) Shadoo PF14999.1 CDI87973.1 - 0.17 11.7 8.1 0.38 10.5 5.6 1.6 1 0 0 1 1 1 0 Shadow of prion protein, neuroprotective SLD3 PF08639.5 CDI87973.1 - 0.73 8.4 6.5 0.94 8.0 4.5 1.1 1 0 0 1 1 1 0 DNA replication regulator SLD3 CoA_transf_3 PF02515.12 CDI87973.1 - 1.1 8.4 6.9 2 7.5 4.7 1.6 1 1 0 1 1 1 0 CoA-transferase family III CBFNT PF08143.6 CDI87973.1 - 6.5 7.9 18.8 7.1 7.8 6.5 2.2 2 0 0 2 2 2 0 CBFNT (NUC161) domain RskA PF10099.4 CDI87973.1 - 8.9 6.0 13.1 30 4.2 9.1 1.8 1 1 0 1 1 1 0 Anti-sigma-K factor rskA YjgP_YjgQ PF03739.9 CDI87975.1 - 0.21 10.2 2.2 0.32 9.6 1.5 1.3 1 1 0 1 1 1 0 Predicted permease YjgP/YjgQ family Methyltransf_23 PF13489.1 CDI87976.1 - 0.085 12.5 0.4 0.15 11.7 0.3 1.4 1 0 0 1 1 1 0 Methyltransferase domain DUF1943 PF09172.6 CDI87976.1 - 0.17 10.7 1.6 12 4.6 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1943) Peptidase_U57 PF05582.7 CDI87976.1 - 0.48 9.3 2.8 0.68 8.8 1.9 1.2 1 0 0 1 1 1 0 YabG peptidase U57 FHIPEP PF00771.15 CDI87976.1 - 0.69 8.1 5.9 0.92 7.7 4.1 1.1 1 0 0 1 1 1 0 FHIPEP family DUF4557 PF15101.1 CDI87976.1 - 2.7 7.7 8.7 2.8 7.7 5.4 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4557) DUF3450 PF11932.3 CDI87976.1 - 3 7.0 18.6 4.2 6.5 12.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF2229 PF09989.4 CDI87976.1 - 3.2 7.1 6.2 8.8 5.7 4.3 1.7 1 1 0 1 1 1 0 CoA enzyme activase uncharacterised domain (DUF2229) PHD_3 PF13922.1 CDI87976.1 - 3.6 7.9 8.8 4.3 7.6 5.4 1.7 2 0 0 2 2 2 0 PHD domain of transcriptional enhancer, Asx DUF3373 PF11853.3 CDI87976.1 - 3.8 5.9 5.6 5.5 5.3 3.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) Androgen_recep PF02166.11 CDI87976.1 - 5.7 5.7 12.9 7.7 5.2 8.9 1.1 1 0 0 1 1 1 0 Androgen receptor Nop53 PF07767.6 CDI87976.1 - 5.8 5.7 15.7 8.1 5.3 10.9 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Erythro_esteras PF05139.9 CDI87976.1 - 6.7 5.8 11.0 68 2.4 0.0 2.2 2 0 0 2 2 2 0 Erythromycin esterase Med15 PF09606.5 CDI87976.1 - 6.9 4.7 19.9 8.5 4.4 13.8 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Med15 PF09606.5 CDI87977.1 - 0.0064 14.7 70.3 0.0083 14.3 48.8 1.2 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal Utp14 PF04615.8 CDI87977.1 - 0.013 13.7 38.5 0.016 13.4 26.7 1.1 1 0 0 1 1 1 0 Utp14 protein Macoilin PF09726.4 CDI87977.1 - 0.034 12.4 49.4 0.04 12.2 34.2 1.1 1 0 0 1 1 1 0 Transmembrane protein DDRGK PF09756.4 CDI87977.1 - 0.98 8.7 37.0 1.6 8.1 25.6 1.3 1 0 0 1 1 1 0 DDRGK domain Asp-B-Hydro_N PF05279.6 CDI87977.1 - 1.1 9.0 26.8 1.5 8.5 18.6 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region DUF4175 PF13779.1 CDI87977.1 - 2.9 5.4 58.9 4.9 4.7 40.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) CRT10 PF08728.5 CDI87977.1 - 8 4.3 23.8 9.1 4.1 16.5 1.1 1 0 0 1 1 1 0 CRT10 LMBR1 PF04791.11 CDI87977.1 - 9.9 4.6 17.0 11 4.4 11.8 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein SR-25 PF10500.4 CDI87978.1 - 0.0033 16.9 11.5 0.0047 16.4 8.0 1.3 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein SR-25 PF10500.4 CDI87979.1 - 0.0053 16.2 15.7 0.0066 15.9 10.9 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein ketoacyl-synt PF00109.21 CDI87979.1 - 0.024 14.0 10.3 0.032 13.7 7.1 1.2 1 0 0 1 1 1 0 Beta-ketoacyl synthase, N-terminal domain Trp_oprn_chp PF09534.5 CDI87979.1 - 0.36 10.4 22.0 0.4 10.2 15.2 1.0 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Alpha-mann_mid PF09261.6 CDI87979.1 - 4.2 7.6 9.8 0.18 12.0 0.9 2.1 2 0 0 2 2 2 0 Alpha mannosidase, middle domain RskA PF10099.4 CDI87979.1 - 4.4 7.0 32.5 4.6 6.9 12.0 2.0 1 1 1 2 2 2 0 Anti-sigma-K factor rskA Cyclin_N PF00134.18 CDI87981.1 - 1e-09 38.0 0.3 3.7e-09 36.2 0.1 1.9 1 1 1 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 CDI87981.1 - 0.00017 21.4 0.1 0.0035 17.2 0.0 2.5 1 1 1 2 2 2 1 Cyclin, C-terminal domain Shadoo PF14999.1 CDI87982.1 - 1.6 8.5 13.3 2.4 8.0 9.2 1.3 1 0 0 1 1 1 0 Shadow of prion protein, neuroprotective SprA-related PF12118.3 CDI87983.1 - 0.029 13.6 53.8 0.033 13.5 37.3 1.1 1 0 0 1 1 1 0 SprA-related family DUF4207 PF13904.1 CDI87983.1 - 0.062 12.6 42.8 0.092 12.1 29.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4207) AAA_23 PF13476.1 CDI87983.1 - 0.44 10.8 20.2 0.58 10.4 14.0 1.1 1 0 0 1 1 1 0 AAA domain DUF4407 PF14362.1 CDI87983.1 - 1.1 8.1 19.2 1.2 8.0 13.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Pex24p PF06398.6 CDI87984.1 - 0.0012 17.7 0.3 0.0019 17.0 0.2 1.2 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin Ycf1 PF05758.7 CDI87984.1 - 0.0017 16.2 1.4 0.0017 16.2 1.0 1.1 1 0 0 1 1 1 1 Ycf1 DUF1980 PF09323.5 CDI87984.1 - 0.0061 16.3 5.1 0.013 15.2 3.5 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1980) Bud13 PF09736.4 CDI87984.1 - 0.018 15.3 14.3 0.025 14.8 9.9 1.2 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex DUF106 PF01956.11 CDI87984.1 - 0.018 14.5 2.0 0.021 14.3 1.4 1.4 1 0 0 1 1 1 0 Integral membrane protein DUF106 SID-1_RNA_chan PF13965.1 CDI87984.1 - 0.049 11.8 1.7 0.07 11.2 1.2 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Tmemb_9 PF05434.6 CDI87984.1 - 0.13 12.0 10.3 0.23 11.1 7.1 1.4 1 0 0 1 1 1 0 TMEM9 Sre PF03125.13 CDI87984.1 - 0.16 10.8 0.6 0.22 10.3 0.4 1.1 1 0 0 1 1 1 0 C. elegans Sre G protein-coupled chemoreceptor LpxB PF02684.10 CDI87984.1 - 0.2 10.2 5.3 0.37 9.3 3.7 1.5 1 0 0 1 1 1 0 Lipid-A-disaccharide synthetase IER PF05760.7 CDI87984.1 - 0.2 11.5 32.2 0.27 11.1 22.3 1.2 1 0 0 1 1 1 0 Immediate early response protein (IER) Plasmodium_Vir PF05795.6 CDI87984.1 - 0.25 10.5 4.2 0.31 10.1 2.9 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Herpes_UL87 PF03043.9 CDI87984.1 - 0.4 9.0 9.8 0.44 8.8 6.8 1.1 1 0 0 1 1 1 0 Herpesvirus UL87 family FimP PF09766.4 CDI87984.1 - 0.86 8.6 24.0 1.2 8.1 16.7 1.1 1 0 0 1 1 1 0 Fms-interacting protein SHR3_chaperone PF08229.6 CDI87984.1 - 0.86 8.5 8.0 1.7 7.5 5.5 1.6 1 0 0 1 1 1 0 ER membrane protein SH3 DUF4446 PF14584.1 CDI87984.1 - 0.96 9.2 7.2 1.8 8.3 5.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) Utp14 PF04615.8 CDI87984.1 - 1.9 6.5 19.9 2.5 6.1 13.8 1.2 1 0 0 1 1 1 0 Utp14 protein DUF4647 PF15504.1 CDI87984.1 - 1.9 7.2 19.1 2.6 6.7 13.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4647) DUF572 PF04502.8 CDI87984.1 - 2 7.5 20.7 2.7 7.1 14.4 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) TRAP_alpha PF03896.11 CDI87984.1 - 2.2 7.2 7.2 0.048 12.6 0.5 1.6 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit eIF-3_zeta PF05091.7 CDI87984.1 - 2.2 6.7 16.0 2.9 6.4 11.1 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Hid1 PF12722.2 CDI87984.1 - 5.9 4.4 19.3 7.7 4.0 13.4 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein ATG27 PF09451.5 CDI87985.1 - 0.0071 15.6 0.3 0.037 13.2 0.0 2.0 2 0 0 2 2 2 1 Autophagy-related protein 27 Shadoo PF14999.1 CDI87985.1 - 0.03 14.1 0.2 0.046 13.5 0.2 1.3 1 0 0 1 1 1 0 Shadow of prion protein, neuroprotective Serinc PF03348.10 CDI87985.1 - 0.03 13.0 19.1 0.023 13.4 4.3 2.2 2 0 0 2 2 2 0 Serine incorporator (Serinc) DUF4010 PF13194.1 CDI87985.1 - 0.031 13.5 3.4 0.26 10.5 0.1 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4010) DUF3675 PF12428.3 CDI87985.1 - 0.032 14.4 1.5 0.032 14.4 1.1 2.8 3 1 0 3 3 1 0 Protein of unknown function (DUF3675) Neur_chan_memb PF02932.11 CDI87985.1 - 0.076 12.8 13.2 0.061 13.2 4.0 2.2 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region DUF2899 PF11449.3 CDI87985.1 - 0.078 12.1 10.3 0.39 9.8 1.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2899) Tim54 PF11711.3 CDI87985.1 - 0.093 11.3 14.6 0.035 12.7 3.2 2.2 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 DUF913 PF06025.7 CDI87985.1 - 0.099 11.3 8.7 0.36 9.5 1.5 2.2 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) DUF4045 PF13254.1 CDI87985.1 - 0.12 11.6 16.0 0.031 13.5 4.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4045) FAM60A PF15396.1 CDI87985.1 - 0.12 12.0 20.1 0.87 9.2 6.7 2.3 2 0 0 2 2 2 0 Protein Family FAM60A HCO3_cotransp PF00955.16 CDI87985.1 - 0.19 10.3 5.1 0.29 9.7 0.6 2.0 2 0 0 2 2 2 0 HCO3- transporter family CD20 PF04103.10 CDI87985.1 - 0.2 11.6 0.1 0.2 11.6 0.0 2.5 2 1 0 2 2 2 0 CD20-like family CKAP2_C PF15297.1 CDI87985.1 - 0.23 10.2 22.3 0.34 9.6 0.3 2.2 2 0 0 2 2 2 0 Cytoskeleton-associated protein 2 C-terminus Folate_carrier PF01770.13 CDI87985.1 - 0.37 9.2 15.0 1.1 7.6 0.4 2.1 2 0 0 2 2 2 0 Reduced folate carrier DUF2370 PF10176.4 CDI87985.1 - 0.44 9.8 12.7 1.4 8.2 4.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2370) DUF2072 PF09845.4 CDI87985.1 - 0.56 10.1 11.0 3.5 7.5 0.3 2.5 2 0 0 2 2 2 0 Zn-ribbon containing protein (DUF2072) DUF3899 PF13038.1 CDI87985.1 - 0.62 10.2 6.7 1.7 8.8 0.2 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF3899) DUF4386 PF14329.1 CDI87985.1 - 0.68 9.3 5.4 1.6 8.1 1.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4386) Ribosomal_60s PF00428.14 CDI87985.1 - 0.71 10.3 10.6 1.3 9.5 7.3 1.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein Caldesmon PF02029.10 CDI87985.1 - 0.79 8.0 17.3 0.042 12.2 3.0 2.1 2 0 0 2 2 2 0 Caldesmon AUX_IAA PF02309.11 CDI87985.1 - 1.2 8.8 20.8 0.16 11.6 5.5 2.2 2 0 0 2 2 2 0 AUX/IAA family Cellulose_synt PF03552.9 CDI87985.1 - 1.2 7.2 6.1 1.2 7.3 1.0 2.0 2 0 0 2 2 2 0 Cellulose synthase NARP1 PF12569.3 CDI87985.1 - 1.7 7.3 26.3 1.1 7.9 1.7 2.1 2 0 0 2 2 2 0 NMDA receptor-regulated protein 1 DUF966 PF06136.8 CDI87985.1 - 1.8 7.8 19.3 0.27 10.5 5.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF966) Cyto_heme_lyase PF01265.12 CDI87985.1 - 1.9 8.0 23.4 2.3 7.7 9.1 2.2 2 0 0 2 2 2 0 Cytochrome c/c1 heme lyase MDFI PF15316.1 CDI87985.1 - 2.7 7.9 14.9 1.7 8.6 3.1 2.4 2 0 0 2 2 2 0 MyoD family inhibitor SPX PF03105.14 CDI87985.1 - 2.9 7.5 26.2 0.038 13.7 6.9 2.1 1 1 0 2 2 2 0 SPX domain RR_TM4-6 PF06459.7 CDI87985.1 - 3.2 7.5 26.2 0.8 9.5 8.7 2.2 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 SpoIIP PF07454.6 CDI87985.1 - 3.3 6.8 19.6 1.8 7.6 0.1 2.2 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) Rtf2 PF04641.7 CDI87985.1 - 3.7 6.6 26.6 1.2 8.2 7.7 2.3 2 0 0 2 2 2 0 Rtf2 RING-finger Nucleoside_tran PF01733.13 CDI87985.1 - 4.3 6.4 7.8 3.7 6.6 2.1 2.1 2 0 0 2 2 2 0 Nucleoside transporter Peroxin-13_N PF04088.8 CDI87985.1 - 5.9 6.8 17.5 3 7.7 0.1 3.1 3 1 0 3 3 2 0 Peroxin 13, N-terminal region DUF702 PF05142.7 CDI87985.1 - 6 7.0 28.6 0.2 11.8 7.2 2.5 3 0 0 3 3 2 0 Domain of unknown function (DUF702) PP_M1 PF03012.9 CDI87985.1 - 8.6 5.6 21.7 4.9 6.4 7.2 2.2 2 0 0 2 2 2 0 Phosphoprotein Vma12 PF11712.3 CDI87985.1 - 9.5 5.9 14.4 0.17 11.6 3.0 2.2 2 0 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase DUF2407_C PF13373.1 CDI87985.1 - 9.7 6.1 14.1 7.4 6.4 0.1 2.5 3 0 0 3 3 2 0 DUF2407 C-terminal domain Med19 PF10278.4 CDI87985.1 - 9.8 5.8 15.3 0.41 10.3 2.5 2.3 2 0 0 2 2 2 0 Mediator of RNA pol II transcription subunit 19 DUF4448 PF14610.1 CDI87988.1 - 0.21 11.0 2.3 0.31 10.5 1.6 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF4448) CDC45 PF02724.9 CDI87989.1 - 0.032 12.2 32.3 0.042 11.9 22.4 1.0 1 0 0 1 1 1 0 CDC45-like protein DUF4045 PF13254.1 CDI87989.1 - 0.074 12.3 27.2 0.098 11.9 18.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) DUF913 PF06025.7 CDI87989.1 - 0.13 10.9 18.3 0.21 10.2 12.7 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Hid1 PF12722.2 CDI87989.1 - 0.21 9.2 36.1 0.28 8.8 25.0 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF572 PF04502.8 CDI87989.1 - 0.37 9.9 30.1 0.55 9.3 20.9 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) Utp14 PF04615.8 CDI87989.1 - 0.61 8.1 41.4 0.79 7.8 28.7 1.1 1 0 0 1 1 1 0 Utp14 protein Herpes_env PF01673.13 CDI87989.1 - 0.64 8.5 26.1 0.9 8.0 18.1 1.2 1 0 0 1 1 1 0 Herpesvirus putative major envelope glycoprotein DUF3357 PF11837.3 CDI87989.1 - 0.68 9.8 25.1 0.44 10.4 3.7 3.3 1 1 1 2 2 1 0 Domain of unknown function (DUF3357) SpoIIIAH PF12685.2 CDI87989.1 - 1.1 8.6 34.1 12 5.3 23.6 2.1 1 1 0 1 1 1 0 SpoIIIAH-like protein SID-1_RNA_chan PF13965.1 CDI87989.1 - 1.2 7.2 25.8 1.5 6.9 17.9 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 PLRV_ORF5 PF01690.12 CDI87989.1 - 1.3 8.0 29.4 1.8 7.6 20.4 1.2 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein HCO3_cotransp PF00955.16 CDI87989.1 - 1.5 7.3 12.4 1.6 7.2 8.6 1.2 1 0 0 1 1 1 0 HCO3- transporter family Raftlin PF15250.1 CDI87989.1 - 1.7 7.0 34.0 2.2 6.6 23.6 1.1 1 0 0 1 1 1 0 Raftlin DUF1510 PF07423.6 CDI87989.1 - 4.5 6.5 47.5 0.81 9.0 28.7 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1510) DUF912 PF06024.7 CDI87989.1 - 5.6 7.0 38.5 0.44 10.6 10.6 2.9 1 1 1 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF1180 PF06679.7 CDI87989.1 - 5.6 6.8 6.6 14 5.5 4.5 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1180) DUF966 PF06136.8 CDI87989.1 - 5.7 6.2 29.3 9.6 5.5 20.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Init_tRNA_PT PF04179.7 CDI87989.1 - 8.4 5.1 25.6 10 4.8 17.8 1.0 1 0 0 1 1 1 0 Initiator tRNA phosphoribosyl transferase SPX PF03105.14 CDI87989.1 - 9.6 5.8 37.4 13 5.4 26.0 1.1 1 0 0 1 1 1 0 SPX domain Ribosomal_60s PF00428.14 CDI87991.1 - 4 7.9 11.0 8.2 6.9 7.6 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein AMP-binding PF00501.23 CDI87991.1 - 5.7 5.2 8.3 6.9 4.9 5.8 1.2 1 0 0 1 1 1 0 AMP-binding enzyme Spt20 PF12090.3 CDI87992.1 - 0.013 14.8 0.2 0.018 14.4 0.1 1.4 1 0 0 1 1 1 0 Spt20 family DUF89 PF01937.14 CDI87992.1 - 0.079 11.7 0.6 0.12 11.1 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF89 Jun PF03957.8 CDI87992.1 - 0.086 12.5 7.3 0.45 10.1 0.3 2.2 2 0 0 2 2 2 0 Jun-like transcription factor Shadoo PF14999.1 CDI87992.1 - 2.7 7.8 20.2 0.12 12.2 1.1 2.4 2 0 0 2 2 2 0 Shadow of prion protein, neuroprotective Pex14_N PF04695.8 CDI87992.1 - 3.5 7.6 12.7 0.053 13.5 2.5 2.3 2 1 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region FimP PF09766.4 CDI87992.1 - 3.5 6.5 14.1 0.072 12.1 3.6 2.0 2 0 0 2 2 2 0 Fms-interacting protein R_equi_Vir PF05526.6 CDI87992.1 - 6.3 6.3 9.7 4.4 6.9 2.6 2.1 2 0 0 2 2 2 0 Rhodococcus equi virulence-associated protein DUF1510 PF07423.6 CDI87993.1 - 0.31 10.3 23.3 0.34 10.2 16.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Serinc PF03348.10 CDI87993.1 - 3.7 6.1 20.3 3.8 6.1 14.1 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) Ctr PF04145.10 CDI87993.1 - 4.2 7.3 13.9 5.9 6.9 9.7 1.2 1 0 0 1 1 1 0 Ctr copper transporter family DUF4484 PF14831.1 CDI87993.1 - 6.2 6.8 13.2 7.5 6.6 9.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4484) Host_attach PF10116.4 CDI87993.1 - 6.5 6.9 17.0 7.5 6.7 11.8 1.1 1 0 0 1 1 1 0 Protein required for attachment to host cells Kei1 PF08552.6 CDI87993.1 - 8.2 6.0 16.3 9.5 5.8 11.3 1.1 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 Baculo_PP31 PF05311.6 CDI87993.1 - 8.3 5.5 22.0 8.8 5.5 15.3 1.0 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) DUF4512 PF14975.1 CDI87993.1 - 8.8 7.2 14.7 12 6.8 10.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4512) DDHD PF02862.12 CDI87993.1 - 9 6.0 22.2 9.6 5.9 15.4 1.0 1 0 0 1 1 1 0 DDHD domain HSP90 PF00183.13 CDI87994.1 - 0.27 9.5 8.3 0.29 9.4 5.8 1.0 1 0 0 1 1 1 0 Hsp90 protein Afi1 PF07792.7 CDI87994.1 - 1.6 8.7 15.9 1.8 8.5 11.0 1.1 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking FYDLN_acid PF09538.5 CDI87994.1 - 2.6 8.6 9.4 2.7 8.6 6.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) PH_4 PF15404.1 CDI87994.1 - 3.2 7.2 12.3 3.4 7.1 8.5 1.1 1 0 0 1 1 1 0 Pleckstrin homology domain Gti1_Pac2 PF09729.4 CDI87994.1 - 4.1 7.2 11.2 4.4 7.1 7.7 1.1 1 0 0 1 1 1 0 Gti1/Pac2 family Paf1 PF03985.8 CDI87994.1 - 4.3 5.9 20.8 4 6.0 14.4 1.0 1 0 0 1 1 1 0 Paf1 DUF1764 PF08576.5 CDI87994.1 - 4.9 7.9 18.0 5.1 7.9 12.4 1.1 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) DUF3381 PF11861.3 CDI87994.1 - 5.2 6.5 17.9 5.1 6.5 12.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) AIF_C PF14721.1 CDI87994.1 - 5.2 7.3 13.3 5.3 7.2 9.2 1.1 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term BRF1 PF07741.8 CDI87994.1 - 5.3 7.3 16.8 6.1 7.1 11.7 1.2 1 0 0 1 1 1 0 Brf1-like TBP-binding domain DUF912 PF06024.7 CDI87994.1 - 5.6 7.0 10.3 6.5 6.8 7.2 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Spore_coat_CotO PF14153.1 CDI87994.1 - 5.6 6.3 24.3 5.6 6.3 16.8 1.1 1 0 0 1 1 1 0 Spore coat protein CotO FimP PF09766.4 CDI87994.1 - 7.3 5.5 29.1 7.6 5.4 20.2 1.1 1 0 0 1 1 1 0 Fms-interacting protein DDHD PF02862.12 CDI87994.1 - 7.5 6.2 16.6 7.1 6.3 11.5 1.0 1 0 0 1 1 1 0 DDHD domain DUF3306 PF11748.3 CDI87994.1 - 7.9 7.1 16.3 7.7 7.2 11.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3306) CobT PF06213.7 CDI87994.1 - 8 5.5 15.7 7.8 5.5 10.9 1.0 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT FLO_LFY PF01698.11 CDI87994.1 - 8.1 5.1 14.8 7.6 5.2 10.2 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein DUF853 PF05872.7 CDI87994.1 - 8.4 4.6 16.5 8.9 4.5 11.5 1.0 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) eIF_4EBP PF05456.6 CDI87994.1 - 9.5 5.9 13.5 12 5.6 9.4 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) PPP4R2 PF09184.6 CDI87994.1 - 9.7 5.6 16.2 9.3 5.7 11.3 1.0 1 0 0 1 1 1 0 PPP4R2 DUF3801 PF12687.2 CDI87995.1 - 0.026 14.0 6.0 0.028 13.9 4.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3801) Peptidase_C37 PF05416.7 CDI87995.1 - 0.064 11.5 5.4 0.073 11.3 3.7 1.1 1 0 0 1 1 1 0 Southampton virus-type processing peptidase Tetraspannin PF00335.15 CDI87995.1 - 0.19 11.0 1.5 0.24 10.6 1.0 1.1 1 0 0 1 1 1 0 Tetraspanin family DUF2217 PF10265.4 CDI87995.1 - 5.5 5.6 23.5 7.4 5.2 16.3 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) Nop25 PF09805.4 CDI87995.1 - 6.3 6.8 8.9 10 6.1 6.2 1.3 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) ECR1_N PF14382.1 CDI87996.1 - 4.3e-08 32.3 0.1 6.6e-08 31.7 0.1 1.3 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region Pex14_N PF04695.8 CDI87996.1 - 0.006 16.6 6.8 0.081 12.9 2.4 2.2 2 0 0 2 2 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region FimP PF09766.4 CDI87996.1 - 0.011 14.8 2.5 0.011 14.8 1.8 1.9 2 0 0 2 2 2 0 Fms-interacting protein DUF2722 PF10846.3 CDI87996.1 - 0.013 14.5 5.1 0.015 14.4 1.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) RAB3GAP2_N PF14655.1 CDI87996.1 - 0.015 14.3 0.5 0.015 14.3 0.4 1.8 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Apt1 PF10351.4 CDI87996.1 - 0.019 13.8 0.6 0.027 13.3 0.4 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain SR-25 PF10500.4 CDI87996.1 - 0.036 13.5 15.4 1 8.8 7.4 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Spt20 PF12090.3 CDI87996.1 - 0.037 13.3 0.4 0.037 13.3 0.3 2.1 2 0 0 2 2 2 0 Spt20 family DUF4557 PF15101.1 CDI87996.1 - 0.042 13.6 0.7 0.042 13.6 0.5 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4557) GntP_permease PF02447.11 CDI87996.1 - 0.085 11.3 0.0 0.11 10.9 0.0 1.1 1 0 0 1 1 1 0 GntP family permease Folliculin PF11704.3 CDI87996.1 - 0.19 11.2 2.4 0.78 9.3 0.9 2.0 2 0 0 2 2 2 0 Vesicle coat protein involved in Golgi to plasma membrane transport DUF3633 PF12315.3 CDI87996.1 - 0.34 10.1 5.1 4.5 6.5 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3633) DUF605 PF04652.11 CDI87996.1 - 0.36 10.1 7.0 0.13 11.6 0.5 2.0 2 0 0 2 2 2 0 Vta1 like DUF3446 PF11928.3 CDI87996.1 - 1 9.5 11.1 6.4 7.0 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3446) Med15 PF09606.5 CDI87996.1 - 1.4 6.9 20.1 0.17 10.0 10.1 1.8 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal Dehydrin PF00257.14 CDI87996.1 - 1.7 8.9 8.1 2.3 8.5 0.1 2.1 2 0 0 2 2 2 0 Dehydrin FCP1_C PF09309.5 CDI87996.1 - 4.4 6.5 9.9 0.25 10.5 1.4 2.0 2 0 0 2 2 2 0 FCP1, C-terminal Memo PF01875.12 CDI87997.1 - 2e-50 171.2 0.0 2.3e-50 170.9 0.0 1.0 1 0 0 1 1 1 1 Memo-like protein Zip PF02535.17 CDI87998.1 - 0.12 11.3 15.7 0.18 10.7 10.9 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter DUF4045 PF13254.1 CDI87998.1 - 8.5 5.5 30.4 9.6 5.3 21.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) PAT1 PF09770.4 CDI87998.1 - 8.5 4.4 79.9 10 4.2 55.4 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Apt1 PF10351.4 CDI87999.1 - 0.31 9.8 8.0 0.49 9.1 5.6 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain Med15 PF09606.5 CDI87999.1 - 1.5 6.9 32.5 1.6 6.8 22.5 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal wnt PF00110.14 CDI88000.1 - 0.013 14.6 0.1 0.016 14.4 0.0 1.0 1 0 0 1 1 1 0 wnt family Glyco_hydro_63 PF03200.11 CDI88000.1 - 0.017 13.0 0.1 0.02 12.7 0.1 1.0 1 0 0 1 1 1 0 Mannosyl oligosaccharide glucosidase Herpes_LMP2 PF07415.6 CDI88000.1 - 0.045 12.3 3.0 0.051 12.1 2.0 1.1 1 0 0 1 1 1 0 Gammaherpesvirus latent membrane protein (LMP2) protein Med15 PF09606.5 CDI88000.1 - 0.62 8.1 35.7 0.77 7.8 24.7 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal MAP65_ASE1 PF03999.7 CDI88000.1 - 1.3 7.5 5.6 1.4 7.3 3.9 1.0 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) RskA PF10099.4 CDI88000.1 - 2.9 7.5 16.8 2 8.0 8.1 2.2 2 0 0 2 2 2 0 Anti-sigma-K factor rskA DUF2615 PF11027.3 CDI88001.1 - 0.14 12.0 7.4 0.2 11.6 5.2 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2615) Rsm1 PF08600.5 CDI88001.1 - 0.68 9.8 3.9 0.78 9.6 2.7 1.1 1 0 0 1 1 1 0 Rsm1-like AAA_23 PF13476.1 CDI88001.1 - 3.5 7.9 13.5 4.1 7.6 9.3 1.2 1 0 0 1 1 1 0 AAA domain CAF-1_p150 PF11600.3 CDI88002.1 - 0.15 11.4 9.8 0.23 10.8 1.1 2.1 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Pol_alpha_B_N PF08418.5 CDI88003.1 - 0.4 10.1 21.4 0.5 9.8 14.8 1.1 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal DUF3439 PF11921.3 CDI88003.1 - 0.88 9.3 6.1 1.2 8.8 4.2 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF3439) Pet20 PF08692.5 CDI88003.1 - 0.89 9.4 5.0 1.3 9.0 3.5 1.3 1 0 0 1 1 1 0 Mitochondrial protein Pet20 Nop25 PF09805.4 CDI88003.1 - 1.2 9.1 25.4 1.5 8.8 17.6 1.2 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) SSP160 PF06933.6 CDI88003.1 - 1.3 6.8 17.6 1.6 6.6 12.2 1.0 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Cwf_Cwc_15 PF04889.7 CDI88003.1 - 1.5 8.4 26.1 2.1 8.0 18.1 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Plasmodium_Vir PF05795.6 CDI88003.1 - 1.9 7.6 17.7 2.4 7.2 12.3 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Bud13 PF09736.4 CDI88003.1 - 2.1 8.6 26.5 2.5 8.3 18.3 1.2 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex PAT1 PF09770.4 CDI88003.1 - 2.5 6.2 43.1 2.6 6.1 29.9 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 POP1 PF06978.6 CDI88003.1 - 3 7.4 15.8 3.6 7.1 10.9 1.2 1 0 0 1 1 1 0 Ribonucleases P/MRP protein subunit POP1 SLD3 PF08639.5 CDI88003.1 - 3.1 6.3 31.8 3.4 6.2 22.0 1.0 1 0 0 1 1 1 0 DNA replication regulator SLD3 BAF1_ABF1 PF04684.8 CDI88003.1 - 3.2 6.4 34.9 4.5 5.9 24.2 1.3 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor DUF4175 PF13779.1 CDI88003.1 - 3.3 5.2 48.9 3.7 5.1 33.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) eIF-3_zeta PF05091.7 CDI88003.1 - 3.9 5.9 24.1 4.3 5.8 16.7 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Spc7_N PF15402.1 CDI88003.1 - 5.6 4.8 31.8 6 4.7 22.0 1.0 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 Totivirus_coat PF05518.6 CDI88003.1 - 6.8 4.3 13.4 8 4.1 9.3 1.0 1 0 0 1 1 1 0 Totivirus coat protein DUF4045 PF13254.1 CDI88003.1 - 6.9 5.8 26.0 7.5 5.7 18.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) GvpL_GvpF PF06386.6 CDI88003.1 - 9.8 5.6 15.2 10 5.6 10.5 1.2 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF BAF1_ABF1 PF04684.8 CDI88004.1 - 0.00061 18.7 16.0 0.00061 18.7 11.1 6.1 1 1 3 4 4 4 1 BAF1 / ABF1 chromatin reorganising factor INO80_Ies4 PF08193.6 CDI88006.1 - 0.0048 16.8 0.6 0.0082 16.0 0.4 1.4 1 0 0 1 1 1 1 INO80 complex subunit Ies4 Vitellogenin_N PF01347.17 CDI88006.1 - 0.0055 15.0 1.8 0.0076 14.5 1.2 1.2 1 0 0 1 1 1 1 Lipoprotein amino terminal region Med15 PF09606.5 CDI88006.1 - 0.02 13.1 9.8 0.022 12.9 6.8 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal RAB3GAP2_N PF14655.1 CDI88006.1 - 0.043 12.8 2.0 0.073 12.0 1.4 1.3 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus AMP-binding PF00501.23 CDI88006.1 - 0.11 10.9 1.1 0.14 10.4 0.7 1.2 1 0 0 1 1 1 0 AMP-binding enzyme Herpes_TAF50 PF03326.8 CDI88006.1 - 0.11 11.3 7.7 0.18 10.7 5.4 1.3 1 0 0 1 1 1 0 Herpesvirus transcription activation factor (transactivator) KBP_C PF12309.3 CDI88006.1 - 0.85 8.5 10.3 0.13 11.2 4.3 1.6 1 1 0 2 2 2 0 KIF-1 binding protein C terminal Prothymosin PF03247.9 CDI88006.1 - 6.2 7.0 34.1 4.7 7.4 8.3 2.4 2 0 0 2 2 2 0 Prothymosin/parathymosin family Macoilin PF09726.4 CDI88006.1 - 8.2 4.5 12.5 11 4.1 8.7 1.1 1 0 0 1 1 1 0 Transmembrane protein IncA PF04156.9 CDI88007.1 - 0.00022 20.8 13.1 0.00025 20.6 9.1 1.0 1 0 0 1 1 1 1 IncA protein Trp_oprn_chp PF09534.5 CDI88007.1 - 0.0037 16.8 8.3 0.0043 16.6 5.7 1.1 1 0 0 1 1 1 1 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Ctr PF04145.10 CDI88007.1 - 0.0081 16.2 2.9 0.0092 16.0 2.0 1.2 1 0 0 1 1 1 1 Ctr copper transporter family VIT1 PF01988.14 CDI88007.1 - 0.012 15.1 4.1 0.014 14.8 2.9 1.1 1 0 0 1 1 1 0 VIT family Shadoo PF14999.1 CDI88007.1 - 0.012 15.4 1.9 0.014 15.2 1.3 1.1 1 0 0 1 1 1 0 Shadow of prion protein, neuroprotective Gag_spuma PF03276.9 CDI88007.1 - 0.019 13.3 20.5 0.018 13.3 14.2 1.0 1 0 0 1 1 1 0 Spumavirus gag protein FHIPEP PF00771.15 CDI88007.1 - 0.021 13.2 6.9 0.022 13.1 4.8 1.0 1 0 0 1 1 1 0 FHIPEP family DUF1980 PF09323.5 CDI88007.1 - 0.028 14.1 7.2 0.028 14.1 5.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) CD20 PF04103.10 CDI88007.1 - 0.036 14.0 5.4 0.052 13.4 3.7 1.4 1 1 0 1 1 1 0 CD20-like family Ribosomal_60s PF00428.14 CDI88007.1 - 0.042 14.2 7.7 0.055 13.8 5.4 1.3 1 0 0 1 1 1 0 60s Acidic ribosomal protein Choline_transpo PF04515.7 CDI88007.1 - 0.073 11.8 0.1 0.082 11.6 0.1 1.1 1 0 0 1 1 1 0 Plasma-membrane choline transporter DUF4557 PF15101.1 CDI88007.1 - 0.092 12.5 20.7 0.092 12.5 14.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) Oleosin PF01277.12 CDI88007.1 - 0.11 12.0 4.9 0.14 11.7 3.4 1.2 1 0 0 1 1 1 0 Oleosin FimP PF09766.4 CDI88007.1 - 0.12 11.4 21.5 0.12 11.4 14.9 1.1 1 0 0 1 1 1 0 Fms-interacting protein R_equi_Vir PF05526.6 CDI88007.1 - 0.12 11.9 12.3 0.13 11.8 8.5 1.0 1 0 0 1 1 1 0 Rhodococcus equi virulence-associated protein OPA3 PF07047.7 CDI88007.1 - 0.13 11.9 9.5 0.15 11.8 6.6 1.1 1 0 0 1 1 1 0 Optic atrophy 3 protein (OPA3) Serinc PF03348.10 CDI88007.1 - 0.16 10.6 13.4 0.17 10.5 9.3 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) FPN1 PF06963.7 CDI88007.1 - 0.16 10.2 4.7 0.18 10.1 3.2 1.0 1 0 0 1 1 1 0 Ferroportin1 (FPN1) Neur_chan_memb PF02932.11 CDI88007.1 - 0.16 11.8 5.9 0.2 11.4 4.1 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Bac_luciferase PF00296.15 CDI88007.1 - 0.17 11.0 7.6 0.19 10.8 5.3 1.0 1 0 0 1 1 1 0 Luciferase-like monooxygenase Folate_carrier PF01770.13 CDI88007.1 - 0.18 10.2 5.9 0.2 10.1 4.1 1.1 1 0 0 1 1 1 0 Reduced folate carrier OATP PF03137.15 CDI88007.1 - 0.18 9.8 7.1 0.18 9.8 4.9 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Peptidase_S49_N PF08496.5 CDI88007.1 - 0.19 11.5 8.9 0.24 11.1 6.1 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF4179 PF13786.1 CDI88007.1 - 0.22 11.7 1.5 0.29 11.3 1.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4179) DUF4367 PF14285.1 CDI88007.1 - 0.22 10.8 2.3 0.27 10.5 1.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4367) DUF2217 PF10265.4 CDI88007.1 - 0.23 10.1 6.6 0.25 10.0 4.5 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) AIF_C PF14721.1 CDI88007.1 - 0.27 11.4 11.4 0.31 11.2 7.9 1.1 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Gastrin PF00918.12 CDI88007.1 - 0.28 11.9 17.3 0.32 11.8 12.0 1.1 1 0 0 1 1 1 0 Gastrin/cholecystokinin family OPT PF03169.10 CDI88007.1 - 0.3 9.4 2.7 0.35 9.2 1.9 1.0 1 0 0 1 1 1 0 OPT oligopeptide transporter protein FLO_LFY PF01698.11 CDI88007.1 - 0.32 9.8 12.5 0.34 9.7 8.7 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein DUF4446 PF14584.1 CDI88007.1 - 0.37 10.5 7.4 0.42 10.4 5.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) DUF3617 PF12276.3 CDI88007.1 - 0.39 10.1 18.4 0.49 9.8 12.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3617) HA2 PF04408.18 CDI88007.1 - 0.45 10.5 5.2 0.64 10.0 3.6 1.3 1 0 0 1 1 1 0 Helicase associated domain (HA2) Blt1 PF12754.2 CDI88007.1 - 0.48 9.9 11.3 0.49 9.9 7.9 1.1 1 0 0 1 1 1 0 Cell-cycle control medial ring component DUF3357 PF11837.3 CDI88007.1 - 0.5 10.2 5.3 1.7 8.5 3.7 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF3357) Tetraspannin PF00335.15 CDI88007.1 - 0.53 9.5 3.6 0.6 9.3 2.5 1.2 1 0 0 1 1 1 0 Tetraspanin family SID-1_RNA_chan PF13965.1 CDI88007.1 - 0.6 8.2 6.5 0.6 8.2 4.5 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DUF913 PF06025.7 CDI88007.1 - 0.62 8.7 9.2 0.63 8.7 6.4 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DUF4231 PF14015.1 CDI88007.1 - 0.74 9.8 8.0 0.84 9.6 5.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4231) Med15 PF09606.5 CDI88007.1 - 1 7.4 44.0 1.1 7.3 30.5 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Chorion_S16 PF05836.7 CDI88007.1 - 1.3 8.9 6.4 1.5 8.7 4.5 1.1 1 0 0 1 1 1 0 Chorion protein S16 ADP_PFK_GK PF04587.10 CDI88007.1 - 1.3 7.1 7.2 1.4 7.0 5.0 1.0 1 0 0 1 1 1 0 ADP-specific Phosphofructokinase/Glucokinase conserved region YfhO PF09586.5 CDI88007.1 - 1.3 6.9 7.6 1.3 6.9 5.3 1.0 1 0 0 1 1 1 0 Bacterial membrane protein YfhO Mem_trans PF03547.13 CDI88007.1 - 1.4 7.1 4.9 1.7 6.8 3.4 1.2 1 0 0 1 1 1 0 Membrane transport protein Hid1 PF12722.2 CDI88007.1 - 1.5 6.3 11.0 1.4 6.5 7.6 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF2232 PF09991.4 CDI88007.1 - 1.8 7.5 10.8 1.9 7.3 7.5 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) DUF3450 PF11932.3 CDI88007.1 - 1.9 7.6 28.8 2 7.5 19.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF844 PF05815.6 CDI88007.1 - 2 7.1 18.3 2.2 7.0 12.7 1.0 1 0 0 1 1 1 0 Baculovirus protein of unknown function (DUF844) MelC1 PF06236.6 CDI88007.1 - 2.3 8.2 9.8 2.9 7.8 6.8 1.3 1 0 0 1 1 1 0 Tyrosinase co-factor MelC1 Pro_Al_protease PF02983.9 CDI88007.1 - 2.3 8.2 11.7 3.3 7.7 8.1 1.2 1 0 0 1 1 1 0 Alpha-lytic protease prodomain Kei1 PF08552.6 CDI88007.1 - 2.3 7.8 10.3 2.5 7.7 7.1 1.1 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 Helicase_RecD PF05127.9 CDI88007.1 - 2.7 7.5 9.6 3.1 7.4 6.6 1.1 1 0 0 1 1 1 0 Helicase Baculo_PP31 PF05311.6 CDI88007.1 - 2.8 7.1 13.0 2.7 7.1 9.0 1.1 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) DUF2946 PF11162.3 CDI88007.1 - 3 8.0 16.0 4.5 7.4 11.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2946) HemX PF04375.9 CDI88007.1 - 3.3 6.1 27.4 3.7 6.0 19.0 1.0 1 0 0 1 1 1 0 HemX DUF3824 PF12868.2 CDI88007.1 - 3.8 8.4 10.4 4.7 8.1 7.2 1.2 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) DDHD PF02862.12 CDI88007.1 - 4 7.1 12.0 4.1 7.1 8.3 1.0 1 0 0 1 1 1 0 DDHD domain Peptidase_U57 PF05582.7 CDI88007.1 - 4.2 6.2 9.9 4.2 6.2 6.8 1.0 1 0 0 1 1 1 0 YabG peptidase U57 DUF3260 PF11658.3 CDI88007.1 - 4.3 5.3 14.0 4.4 5.3 9.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3260) Shisa PF13908.1 CDI88007.1 - 4.3 7.4 13.5 4.7 7.3 9.4 1.1 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Het-C PF07217.6 CDI88007.1 - 4.6 5.3 11.0 4.5 5.3 7.6 1.1 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C Pex16 PF08610.5 CDI88007.1 - 5.1 5.9 10.1 4.8 6.0 7.0 1.1 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) RskA PF10099.4 CDI88007.1 - 5.3 6.7 22.1 9.3 5.9 15.3 1.5 1 1 0 1 1 1 0 Anti-sigma-K factor rskA SpaB_C PF14028.1 CDI88007.1 - 5.5 6.4 9.1 6 6.3 6.3 1.0 1 0 0 1 1 1 0 SpaB C-terminal domain DUF2215 PF10225.4 CDI88007.1 - 6.1 6.2 7.9 6.2 6.1 5.5 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) DUF3367 PF11847.3 CDI88007.1 - 6.4 4.5 9.9 6.7 4.5 6.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3367) Dala_Dala_lig_N PF01820.16 CDI88007.1 - 6.8 7.0 8.2 7.6 6.8 5.7 1.2 1 0 0 1 1 1 0 D-ala D-ala ligase N-terminus SprA-related PF12118.3 CDI88007.1 - 6.8 5.9 37.4 9.4 5.4 25.9 1.2 1 0 0 1 1 1 0 SprA-related family Sec62 PF03839.11 CDI88007.1 - 7.7 5.8 7.5 7.8 5.8 5.2 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 Suf PF05843.9 CDI88007.1 - 8.8 5.9 19.2 9.8 5.8 13.3 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) UPF0560 PF10577.4 CDI88007.1 - 8.9 4.4 20.5 8.4 4.5 14.2 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 PMSI1 PF15322.1 CDI88007.1 - 9.6 5.1 12.8 11 5.0 8.9 1.0 1 0 0 1 1 1 0 Protein missing in infertile sperm 1, putative DUF755 PF05501.6 CDI88008.1 - 0.0034 17.4 31.2 0.0034 17.4 21.6 2.7 2 1 1 3 3 2 1 Domain of unknown function (DUF755) PIG-U PF06728.8 CDI88008.1 - 0.0044 15.9 0.8 0.005 15.7 0.6 1.1 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U DUF2361 PF10153.4 CDI88008.1 - 0.016 15.4 6.9 0.11 12.6 0.6 2.3 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2361) DUF1336 PF07059.7 CDI88008.1 - 0.11 11.8 2.7 3.2 7.1 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1336) DUF572 PF04502.8 CDI88008.1 - 0.25 10.4 21.1 0.32 10.1 14.6 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) UPF0542 PF15086.1 CDI88008.1 - 0.27 10.9 6.3 0.38 10.5 0.3 2.3 2 0 0 2 2 2 0 Uncharacterised protein family UPF0542 DUF2489 PF10675.4 CDI88008.1 - 0.4 10.3 26.6 0.17 11.6 3.4 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2489) Peptidase_S49_N PF08496.5 CDI88008.1 - 0.87 9.3 9.3 7.5 6.3 3.2 2.2 2 0 0 2 2 2 0 Peptidase family S49 N-terminal CAF-1_p150 PF11600.3 CDI88008.1 - 1.5 8.1 29.0 0.8 9.0 10.8 2.1 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Herpes_UL87 PF03043.9 CDI88008.1 - 2 6.7 14.7 2.4 6.4 10.2 1.1 1 0 0 1 1 1 0 Herpesvirus UL87 family Bestrophin PF01062.16 CDI88008.1 - 3.9 6.3 6.2 1.2 8.0 0.4 2.0 2 0 0 2 2 2 0 Bestrophin, RFP-TM, chloride channel DUF2217 PF10265.4 CDI88008.1 - 4.4 5.9 21.3 5.7 5.5 14.8 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) Med15 PF09606.5 CDI88008.1 - 5 5.2 57.8 6.9 4.7 40.1 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Hid1 PF12722.2 CDI88008.1 - 6.3 4.3 22.9 7.8 4.0 15.9 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Helicase_RecD PF05127.9 CDI88008.1 - 7.3 6.1 8.4 9.3 5.8 0.6 2.1 2 0 0 2 2 2 0 Helicase T2SF PF00482.18 CDI88008.1 - 8.2 6.3 9.4 2.3 8.1 2.3 2.1 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein F Apc15p PF05841.6 CDI88008.1 - 9.1 7.0 25.3 6.2 7.5 11.6 2.4 2 0 0 2 2 2 0 Apc15p protein CDC45 PF02724.9 CDI88009.1 - 0.26 9.2 21.0 0.25 9.3 14.5 1.1 1 0 0 1 1 1 0 CDC45-like protein SAGA-Tad1 PF12767.2 CDI88009.1 - 0.38 10.3 20.2 0.48 10.0 14.0 1.4 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit SPX PF03105.14 CDI88009.1 - 0.82 9.3 20.5 0.92 9.2 14.2 1.1 1 0 0 1 1 1 0 SPX domain TFIIF_alpha PF05793.7 CDI88009.1 - 1.3 7.2 20.4 1.5 7.1 14.1 1.0 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) CRT10 PF08728.5 CDI88009.1 - 6.4 4.6 11.0 6.1 4.6 7.6 1.0 1 0 0 1 1 1 0 CRT10 Neur_chan_memb PF02932.11 CDI88009.1 - 7.3 6.4 19.9 8 6.2 13.8 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region SOBP PF15279.1 CDI88009.1 - 7.7 6.8 26.4 9.2 6.5 18.3 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein PLRV_ORF5 PF01690.12 CDI88009.1 - 9.9 5.1 31.2 11 5.0 21.6 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein SR-25 PF10500.4 CDI88011.1 - 3.6e-06 26.6 31.4 4.1e-06 26.4 21.8 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein DUF3474 PF11960.3 CDI88011.1 - 0.071 13.1 13.1 0.11 12.4 9.1 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF3474) CDC45 PF02724.9 CDI88011.1 - 0.31 9.0 27.2 0.32 8.9 18.8 1.0 1 0 0 1 1 1 0 CDC45-like protein Suf PF05843.9 CDI88011.1 - 0.37 10.4 29.5 0.43 10.2 20.5 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Macoilin PF09726.4 CDI88011.1 - 0.44 8.7 22.8 0.54 8.4 15.8 1.2 1 0 0 1 1 1 0 Transmembrane protein MIP-T3 PF10243.4 CDI88011.1 - 0.74 8.2 31.8 0.85 8.0 22.1 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Corona_nucleoca PF00937.13 CDI88011.1 - 1.5 7.7 32.3 1.6 7.5 22.4 1.1 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein Cwf_Cwc_15 PF04889.7 CDI88011.1 - 1.8 8.1 25.4 2.1 8.0 17.6 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Nop14 PF04147.7 CDI88011.1 - 1.8 6.3 20.7 2 6.2 14.3 1.0 1 0 0 1 1 1 0 Nop14-like family DUF4614 PF15391.1 CDI88011.1 - 2.4 7.9 26.6 2.7 7.7 18.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) Tim54 PF11711.3 CDI88011.1 - 2.5 6.6 14.6 3.1 6.2 10.1 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 BNIP3 PF06553.7 CDI88011.1 - 2.9 7.2 26.2 3.5 6.9 18.2 1.3 1 0 0 1 1 1 0 BNIP3 SpaB_C PF14028.1 CDI88011.1 - 3.1 7.2 5.4 3.3 7.1 3.8 1.2 1 0 0 1 1 1 0 SpaB C-terminal domain CAF-1_p150 PF11600.3 CDI88011.1 - 3.2 7.0 32.9 4.4 6.6 22.8 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal FLO_LFY PF01698.11 CDI88011.1 - 3.3 6.4 19.9 3.4 6.4 13.8 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein DUF1777 PF08648.7 CDI88011.1 - 3.3 7.3 21.8 4.2 7.0 15.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) AUX_IAA PF02309.11 CDI88011.1 - 5.8 6.5 21.1 7.4 6.2 14.7 1.2 1 0 0 1 1 1 0 AUX/IAA family Nop53 PF07767.6 CDI88011.1 - 6.9 5.5 26.4 7.5 5.4 18.3 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) CAF-1_p150 PF11600.3 CDI88012.1 - 0.062 12.6 33.8 0.078 12.3 23.4 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Med15 PF09606.5 CDI88012.1 - 0.1 10.7 98.1 0.12 10.5 68.0 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal PCEMA1 PF07418.6 CDI88012.1 - 0.58 9.4 11.9 0.58 9.4 8.2 1.1 1 0 0 1 1 1 0 Acidic phosphoprotein precursor PCEMA1 NPR3 PF03666.8 CDI88012.1 - 2.3 6.6 26.4 2.5 6.5 18.3 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 OPT PF03169.10 CDI88012.1 - 5.9 5.1 8.1 20 3.4 5.6 1.7 1 1 0 1 1 1 0 OPT oligopeptide transporter protein GPCR_chapero_1 PF11904.3 CDI88012.1 - 6.9 5.7 24.9 7.7 5.5 17.2 1.1 1 0 0 1 1 1 0 GPCR-chaperone RNA_pol_3_Rpc31 PF11705.3 CDI88012.1 - 7.5 6.4 22.3 10 6.0 15.5 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 DUF4252 PF14060.1 CDI88013.1 - 0.9 9.0 9.7 1 8.8 6.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4252) DUF3337 PF11816.3 CDI88013.1 - 1.4 8.2 17.9 1.5 8.1 12.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3337) Cwf_Cwc_15 PF04889.7 CDI88013.1 - 4.1 7.0 25.7 4.6 6.8 17.8 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Trypan_glycop_C PF10659.4 CDI88013.1 - 7.5 6.9 16.2 0.84 9.9 3.1 2.2 2 0 0 2 2 2 0 Trypanosome variant surface glycoprotein C-terminal domain PAT1 PF09770.4 CDI88014.1 - 0.0027 16.0 69.4 0.0031 15.8 48.1 1.1 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 SOBP PF15279.1 CDI88014.1 - 0.025 14.9 34.6 0.028 14.8 24.0 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein Med15 PF09606.5 CDI88014.1 - 0.064 11.4 94.9 0.068 11.3 65.8 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Utp14 PF04615.8 CDI88014.1 - 0.1 10.7 48.7 0.13 10.4 33.8 1.1 1 0 0 1 1 1 0 Utp14 protein SprA-related PF12118.3 CDI88014.1 - 0.12 11.7 77.9 0.22 10.7 54.0 1.4 1 0 0 1 1 1 0 SprA-related family GAGA_bind PF06217.7 CDI88014.1 - 0.17 11.8 34.9 0.19 11.6 24.2 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family MRP-S31 PF15433.1 CDI88014.1 - 0.49 9.7 40.8 0.79 9.0 28.3 1.3 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 Ycf1 PF05758.7 CDI88014.1 - 0.55 7.8 41.0 0.64 7.6 28.4 1.1 1 0 0 1 1 1 0 Ycf1 TFIIA PF03153.8 CDI88014.1 - 0.6 9.9 61.6 0.74 9.6 42.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Herpes_env PF01673.13 CDI88014.1 - 0.95 7.9 22.2 1.4 7.4 15.4 1.4 1 0 0 1 1 1 0 Herpesvirus putative major envelope glycoprotein DUF3843 PF12954.2 CDI88014.1 - 1.3 7.9 21.3 1.7 7.5 14.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3843) Lin-8 PF03353.10 CDI88014.1 - 2.1 7.5 45.7 2.6 7.2 31.7 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist eIF-3_zeta PF05091.7 CDI88014.1 - 2.3 6.7 42.3 3.3 6.2 29.3 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) WTX PF09422.5 CDI88014.1 - 2.8 6.7 28.4 3.3 6.5 19.7 1.1 1 0 0 1 1 1 0 WTX protein DUF572 PF04502.8 CDI88014.1 - 3.1 6.9 43.3 4.2 6.4 30.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF1675 PF07897.6 CDI88014.1 - 6.3 6.5 33.3 7.9 6.2 23.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) DUF4551 PF15087.1 CDI88014.1 - 6.6 4.9 33.3 7.8 4.7 23.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Hid1 PF12722.2 CDI88014.1 - 7 4.1 42.8 9 3.8 29.7 1.3 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein MIP-T3 PF10243.4 CDI88015.1 - 7.1 4.9 26.4 7.7 4.8 18.3 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DUF2776 PF10951.3 CDI88017.1 - 0.0015 17.6 0.3 0.002 17.2 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2776) Med15 PF09606.5 CDI88017.1 - 0.011 14.0 69.0 0.013 13.7 47.8 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DDHD PF02862.12 CDI88017.1 - 0.02 14.6 9.9 0.027 14.2 6.8 1.3 1 0 0 1 1 1 0 DDHD domain PAT1 PF09770.4 CDI88017.1 - 0.16 10.2 49.4 0.17 10.1 34.3 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TFIIA PF03153.8 CDI88017.1 - 0.51 10.1 33.4 0.58 9.9 23.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF912 PF06024.7 CDI88017.1 - 0.65 10.0 12.8 0.13 12.3 1.3 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) TMEM51 PF15345.1 CDI88017.1 - 0.71 9.5 19.4 1 9.0 13.5 1.2 1 0 0 1 1 1 0 Transmembrane protein 51 Presenilin PF01080.12 CDI88017.1 - 1.5 7.5 6.4 1.7 7.3 4.4 1.1 1 0 0 1 1 1 0 Presenilin FAM60A PF15396.1 CDI88017.1 - 9.5 5.8 15.8 14 5.3 11.0 1.3 1 0 0 1 1 1 0 Protein Family FAM60A DUF4414 PF14377.1 CDI88018.1 - 0.033 14.1 12.8 0.04 13.8 8.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4414) Hep_59 PF07052.6 CDI88018.1 - 0.12 12.7 7.7 0.12 12.7 5.3 1.1 1 0 0 1 1 1 0 Hepatocellular carcinoma-associated antigen 59 Ripply PF14998.1 CDI88018.1 - 0.17 12.0 7.0 0.2 11.7 4.8 1.2 1 1 0 1 1 1 0 Transcription Regulator FliE PF02049.13 CDI88018.1 - 0.22 11.5 10.8 0.26 11.3 7.5 1.1 1 0 0 1 1 1 0 Flagellar hook-basal body complex protein FliE BRF1 PF07741.8 CDI88018.1 - 0.24 11.6 8.6 0.3 11.3 5.9 1.2 1 0 0 1 1 1 0 Brf1-like TBP-binding domain DUF3734 PF12536.3 CDI88018.1 - 0.29 11.2 7.4 0.1 12.7 2.9 1.7 1 1 1 2 2 2 0 Patatin phospholipase CLPTM1 PF05602.7 CDI88018.1 - 0.31 9.7 2.6 0.27 9.8 1.8 1.1 1 0 0 1 1 1 0 Cleft lip and palate transmembrane protein 1 (CLPTM1) DUF2361 PF10153.4 CDI88018.1 - 0.34 11.1 9.4 0.37 10.9 6.5 1.1 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2361) CDC37_N PF03234.9 CDI88018.1 - 0.64 10.3 6.6 0.72 10.1 4.6 1.0 1 0 0 1 1 1 0 Cdc37 N terminal kinase binding Spt20 PF12090.3 CDI88018.1 - 0.9 8.8 10.0 0.92 8.8 7.0 1.1 1 0 0 1 1 1 0 Spt20 family Mmp37 PF09139.6 CDI88018.1 - 0.92 8.4 6.1 0.95 8.4 4.2 1.0 1 0 0 1 1 1 0 Mitochondrial matrix Mmp37 DUF912 PF06024.7 CDI88018.1 - 0.95 9.5 3.7 1.2 9.2 2.5 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) OmpH PF03938.9 CDI88018.1 - 0.97 9.3 23.3 1.1 9.2 16.1 1.0 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) RAB3GAP2_N PF14655.1 CDI88018.1 - 1.1 8.2 9.2 1.1 8.1 6.4 1.1 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus LMBR1 PF04791.11 CDI88018.1 - 1.1 7.7 3.1 1 7.8 2.1 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein Fes1 PF08609.5 CDI88018.1 - 1.4 9.4 4.4 1.4 9.4 3.1 1.1 1 0 0 1 1 1 0 Nucleotide exchange factor Fes1 FimP PF09766.4 CDI88018.1 - 1.5 7.7 12.2 1.6 7.7 8.4 1.1 1 0 0 1 1 1 0 Fms-interacting protein DUF1682 PF07946.9 CDI88018.1 - 1.6 7.5 9.4 1.5 7.5 6.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Pex14_N PF04695.8 CDI88018.1 - 1.7 8.6 8.5 1.9 8.5 5.9 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Dus PF01207.12 CDI88018.1 - 1.8 7.2 9.2 2.1 7.0 6.4 1.1 1 0 0 1 1 1 0 Dihydrouridine synthase (Dus) GRIN_C PF15235.1 CDI88018.1 - 2.3 8.2 9.1 2.4 8.2 6.3 1.2 1 0 0 1 1 1 0 G protein-regulated inducer of neurite outgrowth C-terminus FCP1_C PF09309.5 CDI88018.1 - 2.7 7.2 6.3 2.5 7.3 4.4 1.1 1 0 0 1 1 1 0 FCP1, C-terminal OATP PF03137.15 CDI88018.1 - 3.5 5.5 5.0 3.4 5.6 3.5 1.0 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family SGT1 PF07093.6 CDI88018.1 - 4.2 5.6 8.9 4.6 5.4 6.1 1.0 1 0 0 1 1 1 0 SGT1 protein Folate_carrier PF01770.13 CDI88018.1 - 4.8 5.5 5.5 5.2 5.4 3.8 1.0 1 0 0 1 1 1 0 Reduced folate carrier 5-nucleotidase PF06189.7 CDI88018.1 - 5.1 5.8 7.2 5.1 5.8 5.0 1.1 1 0 0 1 1 1 0 5'-nucleotidase DUF4543 PF15076.1 CDI88018.1 - 5.7 7.0 9.3 9.1 6.4 6.5 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4543) Pex26 PF07163.7 CDI88018.1 - 6.3 5.6 7.2 6.6 5.5 5.0 1.1 1 0 0 1 1 1 0 Pex26 protein 7tm_7 PF08395.7 CDI88018.1 - 6.4 5.6 9.9 6.5 5.6 6.9 1.0 1 0 0 1 1 1 0 7tm Chemosensory receptor Suf PF05843.9 CDI88018.1 - 6.6 6.3 14.3 7.3 6.2 9.9 1.0 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) SprA-related PF12118.3 CDI88019.1 - 1.2e-06 28.0 23.9 1.2e-06 28.0 16.5 1.6 2 0 0 2 2 1 1 SprA-related family PAT1 PF09770.4 CDI88019.1 - 0.0076 14.5 53.0 0.013 13.8 36.7 1.3 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 SAGA-Tad1 PF12767.2 CDI88019.1 - 0.0084 15.8 16.7 0.012 15.2 11.6 1.4 1 0 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit DUF4045 PF13254.1 CDI88019.1 - 0.025 13.8 13.5 0.036 13.3 9.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Ribosomal_60s PF00428.14 CDI88019.1 - 0.2 12.0 25.1 0.32 11.4 2.6 2.4 2 0 0 2 2 2 0 60s Acidic ribosomal protein Hid1 PF12722.2 CDI88019.1 - 0.24 9.0 15.1 0.28 8.8 10.4 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Orbi_VP6 PF01516.11 CDI88019.1 - 0.54 9.2 11.7 0.79 8.7 8.1 1.2 1 0 0 1 1 1 0 Orbivirus helicase VP6 FAM60A PF15396.1 CDI88019.1 - 0.57 9.8 13.7 0.8 9.4 9.5 1.1 1 0 0 1 1 1 0 Protein Family FAM60A DUF4175 PF13779.1 CDI88019.1 - 0.64 7.6 55.9 0.91 7.1 38.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) TFIIA PF03153.8 CDI88019.1 - 1.2 8.9 40.2 0.15 11.9 24.1 1.8 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit RR_TM4-6 PF06459.7 CDI88019.1 - 1.4 8.7 16.2 1.9 8.3 11.2 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 eIF-3_zeta PF05091.7 CDI88019.1 - 1.9 6.9 24.1 2.5 6.6 16.7 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) GAGA_bind PF06217.7 CDI88019.1 - 2.5 7.9 19.4 3.6 7.4 13.5 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family Cyto_heme_lyase PF01265.12 CDI88019.1 - 3.2 7.2 21.5 5 6.6 14.9 1.2 1 0 0 1 1 1 0 Cytochrome c/c1 heme lyase Shadoo PF14999.1 CDI88019.1 - 3.8 7.3 31.5 1.3 8.9 6.1 3.2 3 0 0 3 3 3 0 Shadow of prion protein, neuroprotective AUX_IAA PF02309.11 CDI88019.1 - 4.2 7.0 14.6 6.4 6.4 10.1 1.3 1 0 0 1 1 1 0 AUX/IAA family Membralin PF09746.4 CDI88019.1 - 5.5 5.9 5.8 6.9 5.5 4.0 1.1 1 0 0 1 1 1 0 Tumour-associated protein FLO_LFY PF01698.11 CDI88019.1 - 5.5 5.7 18.1 7.5 5.2 12.5 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein Zip PF02535.17 CDI88019.1 - 6.2 5.7 8.4 9.4 5.1 5.8 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Presenilin PF01080.12 CDI88019.1 - 7.3 5.3 9.3 9.6 4.9 6.4 1.1 1 0 0 1 1 1 0 Presenilin GPCR_chapero_1 PF11904.3 CDI88019.1 - 7.7 5.5 17.2 9.9 5.1 11.9 1.1 1 0 0 1 1 1 0 GPCR-chaperone DSPc PF00782.15 CDI88020.1 - 1.6e-10 40.7 0.0 2.2e-10 40.2 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Secretin_N_2 PF07655.8 CDI88020.1 - 1.2e-05 25.6 5.5 1.6e-05 25.2 3.8 1.1 1 0 0 1 1 1 1 Secretin N-terminal domain Y_phosphatase PF00102.22 CDI88020.1 - 7.1e-05 22.2 0.0 8.3e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 CDI88020.1 - 0.00092 19.2 0.0 0.0011 18.9 0.0 1.2 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.1 CDI88020.1 - 0.007 16.6 0.2 0.0086 16.3 0.2 1.4 1 1 0 1 1 1 1 Tyrosine phosphatase family TatD_DNase PF01026.16 CDI88020.1 - 0.013 14.7 0.0 0.014 14.5 0.0 1.1 1 0 0 1 1 1 0 TatD related DNase DUF515 PF04415.7 CDI88020.1 - 0.56 8.3 3.6 0.67 8.1 2.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) SSP160 PF06933.6 CDI88020.1 - 0.69 7.8 8.2 0.87 7.4 5.7 1.0 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Macoilin PF09726.4 CDI88020.1 - 1.9 6.6 5.7 2.3 6.3 4.0 1.1 1 0 0 1 1 1 0 Transmembrane protein GAS PF13851.1 CDI88021.1 - 1.1e-05 24.7 22.2 0.00014 21.1 2.3 3.0 3 0 0 3 3 3 2 Growth-arrest specific micro-tubule binding WEMBL PF05701.6 CDI88021.1 - 1.2e-05 24.0 24.5 0.0014 17.2 4.5 2.1 2 0 0 2 2 2 2 Weak chloroplast movement under blue light HR1 PF02185.11 CDI88021.1 - 0.0021 17.7 0.8 0.0021 17.7 0.6 3.4 3 1 0 3 3 3 1 Hr1 repeat CENP-F_leu_zip PF10473.4 CDI88021.1 - 0.0023 17.8 23.6 0.067 13.0 0.3 3.2 3 0 0 3 3 3 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Occludin_ELL PF07303.8 CDI88021.1 - 0.0024 18.5 13.0 0.0035 18.0 1.1 3.1 3 0 0 3 3 3 1 Occludin homology domain HOOK PF05622.7 CDI88021.1 - 0.0033 15.3 14.0 0.046 11.5 0.8 2.1 2 0 0 2 2 2 2 HOOK protein HALZ PF02183.13 CDI88021.1 - 0.0039 16.8 29.3 0.015 15.0 1.6 5.2 5 0 0 5 5 5 2 Homeobox associated leucine zipper MAD PF05557.8 CDI88021.1 - 0.0039 15.3 12.8 0.041 11.9 1.8 2.2 2 0 0 2 2 2 2 Mitotic checkpoint protein TMF_TATA_bd PF12325.3 CDI88021.1 - 0.0054 16.4 20.7 0.3 10.8 2.8 3.1 3 0 0 3 3 3 1 TATA element modulatory factor 1 TATA binding Phage_GP20 PF06810.6 CDI88021.1 - 0.0057 16.1 25.8 0.17 11.3 3.5 3.1 3 0 0 3 3 3 2 Phage minor structural protein GP20 DUF3166 PF11365.3 CDI88021.1 - 0.0068 16.8 12.2 0.045 14.1 1.3 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3166) Cob_adeno_trans PF01923.13 CDI88021.1 - 0.008 15.9 5.1 0.04 13.6 0.1 2.5 3 0 0 3 3 2 1 Cobalamin adenosyltransferase HAP1_N PF04849.8 CDI88021.1 - 0.0094 14.9 11.4 0.025 13.5 2.9 2.2 2 0 0 2 2 2 1 HAP1 N-terminal conserved region APG6 PF04111.7 CDI88021.1 - 0.011 14.8 15.0 0.18 10.8 2.8 2.3 2 0 0 2 2 2 0 Autophagy protein Apg6 Kinesin-relat_1 PF12711.2 CDI88021.1 - 0.014 15.8 16.0 1.8 9.0 0.0 3.9 3 1 0 3 3 3 0 Kinesin motor DUF904 PF06005.7 CDI88021.1 - 0.014 15.6 27.7 0.25 11.6 6.4 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF904) NUDE_C PF04880.8 CDI88021.1 - 0.021 15.2 2.7 2.9 8.2 0.1 2.4 2 0 0 2 2 2 0 NUDE protein, C-terminal conserved region IncA PF04156.9 CDI88021.1 - 0.025 14.1 22.3 0.59 9.7 2.2 2.9 1 1 1 2 2 2 0 IncA protein TSC22 PF01166.13 CDI88021.1 - 0.031 14.2 14.8 1.3 9.0 1.7 3.7 3 1 0 3 3 3 0 TSC-22/dip/bun family CCDC-167 PF15188.1 CDI88021.1 - 0.042 13.7 13.4 2.3 8.2 1.9 3.3 3 0 0 3 3 3 0 Coiled-coil domain-containing protein 167 Lzipper-MIP1 PF14389.1 CDI88021.1 - 0.044 13.9 19.0 0.094 12.8 3.3 3.3 3 1 0 3 3 3 0 Leucine-zipper of ternary complex factor MIP1 DivIC PF04977.10 CDI88021.1 - 0.068 12.6 25.2 0.21 11.1 4.6 3.8 3 1 0 3 3 3 0 Septum formation initiator FlxA PF14282.1 CDI88021.1 - 0.087 12.7 17.8 0.42 10.5 2.0 3.4 3 1 0 3 3 3 0 FlxA-like protein DUF4407 PF14362.1 CDI88021.1 - 0.093 11.6 18.6 0.27 10.1 5.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) IL11 PF07400.6 CDI88021.1 - 0.12 11.9 0.6 0.26 10.8 0.3 1.7 1 1 1 2 2 2 0 Interleukin 11 Seryl_tRNA_N PF02403.17 CDI88021.1 - 0.12 12.3 20.2 1 9.4 3.1 3.3 3 0 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Tnp_P_element PF12017.3 CDI88021.1 - 0.13 11.5 4.7 4.8 6.3 0.0 3.0 3 0 0 3 3 3 0 Transposase protein FliD_N PF02465.13 CDI88021.1 - 0.13 12.6 14.5 1.6 9.1 2.6 2.6 2 1 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus bZIP_1 PF00170.16 CDI88021.1 - 0.14 12.1 23.3 7 6.6 3.2 4.9 3 2 2 5 5 5 0 bZIP transcription factor MbeD_MobD PF04899.7 CDI88021.1 - 0.16 11.9 9.6 0.94 9.4 0.7 3.4 3 1 0 3 3 3 0 MbeD/MobD like CCDC155 PF14662.1 CDI88021.1 - 0.19 11.3 22.4 2.1 7.9 1.5 2.9 2 1 0 2 2 2 0 Coiled-coil region of CCDC155 DUF2353 PF09789.4 CDI88021.1 - 0.23 10.7 17.3 0.2 10.8 4.2 2.7 2 1 0 2 2 2 0 Uncharacterized coiled-coil protein (DUF2353) Rho_Binding PF08912.6 CDI88021.1 - 0.23 11.7 0.2 0.23 11.7 0.1 3.6 3 1 0 3 3 3 0 Rho Binding M_domain PF12938.2 CDI88021.1 - 0.29 10.9 5.4 4.6 6.9 3.7 2.3 1 1 0 1 1 1 0 M domain of GW182 Fzo_mitofusin PF04799.8 CDI88021.1 - 0.38 10.1 13.2 0.69 9.2 1.8 2.9 3 0 0 3 3 3 0 fzo-like conserved region LOH1CR12 PF10158.4 CDI88021.1 - 0.53 10.0 8.2 2.9 7.7 0.2 3.1 3 0 0 3 3 3 0 Tumour suppressor protein MscS_porin PF12795.2 CDI88021.1 - 0.6 9.3 21.3 0.31 10.3 1.9 3.2 3 0 0 3 3 3 0 Mechanosensitive ion channel porin domain Mnd1 PF03962.10 CDI88021.1 - 0.71 9.5 25.1 0.74 9.4 3.6 3.0 2 1 0 3 3 3 0 Mnd1 family E2R135 PF11570.3 CDI88021.1 - 0.8 9.7 17.9 0.14 12.2 3.0 2.5 2 1 0 2 2 2 0 Coiled-coil receptor-binding R-domain of colicin E2 Filament PF00038.16 CDI88021.1 - 1 8.7 18.8 0.41 10.0 1.1 2.6 2 1 0 2 2 2 0 Intermediate filament protein DUF972 PF06156.8 CDI88021.1 - 1.1 9.6 16.0 4.2 7.7 0.6 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF972) Spc7 PF08317.6 CDI88021.1 - 1.1 7.8 13.8 0.26 9.9 0.4 2.5 2 1 0 2 2 2 0 Spc7 kinetochore protein DUF4613 PF15390.1 CDI88021.1 - 1.1 7.3 5.2 2.4 6.2 3.3 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4613) PilJ PF13675.1 CDI88021.1 - 1.2 9.4 11.6 5.4 7.3 0.2 2.9 3 0 0 3 3 3 0 Type IV pili methyl-accepting chemotaxis transducer N-term L31 PF09784.4 CDI88021.1 - 1.4 8.9 3.7 2.5 8.2 0.3 2.3 2 0 0 2 2 2 0 Mitochondrial ribosomal protein L31 NPV_P10 PF05531.7 CDI88021.1 - 1.5 9.0 10.9 0.59 10.4 0.9 3.0 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein bZIP_Maf PF03131.12 CDI88021.1 - 1.9 8.8 19.7 4.7 7.5 3.3 3.5 3 1 0 3 3 3 0 bZIP Maf transcription factor DUF479 PF04336.7 CDI88021.1 - 2.5 8.2 5.8 8.4 6.5 0.4 2.4 2 0 0 2 2 2 0 Protein of unknown function, DUF479 Seadorna_VP6 PF07407.6 CDI88021.1 - 3 6.5 5.5 2.2 6.9 0.2 2.1 2 0 0 2 2 2 0 Seadornavirus VP6 protein Tup_N PF08581.5 CDI88021.1 - 3.7 7.8 13.7 4.7 7.4 0.5 4.0 3 2 1 4 4 4 0 Tup N-terminal DUF342 PF03961.8 CDI88021.1 - 4.4 5.5 11.8 5.2 5.3 0.7 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF342) Syntaxin-6_N PF09177.6 CDI88021.1 - 4.6 7.7 10.1 3 8.3 0.6 2.9 3 0 0 3 3 3 0 Syntaxin 6, N-terminal MIS13 PF08202.6 CDI88021.1 - 5.1 6.0 10.2 1.3 8.0 2.2 2.0 2 0 0 2 2 2 0 Mis12-Mtw1 protein family DUF4140 PF13600.1 CDI88021.1 - 5.8 7.4 25.4 8 6.9 0.2 3.8 3 2 0 3 3 3 0 N-terminal domain of unknown function (DUF4140) IFT57 PF10498.4 CDI88021.1 - 6 5.4 13.7 0.59 8.8 2.7 2.4 3 0 0 3 3 3 0 Intra-flagellar transport protein 57 THOC7 PF05615.8 CDI88021.1 - 8.9 6.5 20.5 0.061 13.5 2.7 2.7 3 0 0 3 3 2 0 Tho complex subunit 7 FLO_LFY PF01698.11 CDI88022.1 - 0.58 8.9 5.0 0.66 8.7 3.5 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein DUF4079 PF13301.1 CDI88023.1 - 0.02 14.8 2.3 0.024 14.6 1.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4079) PBP1_TM PF14812.1 CDI88023.1 - 0.028 14.7 5.8 0.11 12.7 4.0 1.9 1 1 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF2370 PF10176.4 CDI88023.1 - 0.043 13.1 0.2 0.065 12.5 0.2 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2370) DUF979 PF06166.7 CDI88023.1 - 0.054 12.4 0.2 0.06 12.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF979) DUF3382 PF11862.3 CDI88023.1 - 0.059 13.2 0.2 0.091 12.6 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3382) DcuC PF03606.10 CDI88023.1 - 0.065 11.4 3.2 0.024 12.9 0.7 1.4 1 1 1 2 2 2 0 C4-dicarboxylate anaerobic carrier Senescence_reg PF04520.8 CDI88023.1 - 0.14 12.6 3.7 0.2 12.1 2.6 1.3 1 0 0 1 1 1 0 Senescence regulator DUF3899 PF13038.1 CDI88023.1 - 0.27 11.4 2.1 0.51 10.5 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3899) FAM60A PF15396.1 CDI88023.1 - 0.34 10.6 3.3 0.49 10.0 2.3 1.2 1 0 0 1 1 1 0 Protein Family FAM60A DDHD PF02862.12 CDI88023.1 - 0.41 10.4 4.2 0.57 9.9 2.9 1.2 1 0 0 1 1 1 0 DDHD domain eIF-3_zeta PF05091.7 CDI88023.1 - 0.43 9.1 11.4 0.47 9.0 7.9 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Presenilin PF01080.12 CDI88023.1 - 0.57 8.9 2.8 0.65 8.7 1.9 1.2 1 0 0 1 1 1 0 Presenilin DUF4366 PF14283.1 CDI88023.1 - 0.61 9.4 7.5 1.5 8.1 5.2 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4366) Herpes_env PF01673.13 CDI88023.1 - 0.68 8.4 7.9 0.76 8.2 5.5 1.0 1 0 0 1 1 1 0 Herpesvirus putative major envelope glycoprotein Neur_chan_memb PF02932.11 CDI88023.1 - 0.71 9.7 3.4 0.78 9.5 2.3 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region CD20 PF04103.10 CDI88023.1 - 1.5 8.7 4.0 4.4 7.2 2.7 1.8 1 1 0 1 1 1 0 CD20-like family DUF912 PF06024.7 CDI88023.1 - 1.7 8.7 10.1 0.085 12.9 1.0 2.2 1 1 1 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Hist_deacetyl PF00850.14 CDI88023.1 - 1.8 7.7 4.4 2 7.6 3.1 1.1 1 0 0 1 1 1 0 Histone deacetylase domain DUF2201_N PF13203.1 CDI88023.1 - 1.9 7.6 13.4 2.2 7.3 9.3 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain Vfa1 PF08432.5 CDI88023.1 - 5 7.1 13.8 7.6 6.5 9.6 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 RskA PF10099.4 CDI88023.1 - 5.5 6.6 13.7 1.8 8.2 5.8 2.0 1 1 1 2 2 2 0 Anti-sigma-K factor rskA DUF2899 PF11449.3 CDI88023.1 - 6.3 5.8 5.5 9.5 5.2 3.8 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2899) HA2 PF04408.18 CDI88023.1 - 9 6.3 7.3 8.5 6.4 3.7 2.0 2 1 0 2 2 1 0 Helicase associated domain (HA2) DUF3628 PF12300.3 CDI88024.1 - 0.23 11.4 17.1 0.27 11.2 11.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3628) LMBR1 PF04791.11 CDI88024.1 - 5.9 5.3 6.1 5.9 5.3 4.3 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF3807 PF12720.2 CDI88024.1 - 6.5 6.8 17.8 8.1 6.5 12.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) DUF2796 PF10986.3 CDI88024.1 - 8.3 6.3 17.1 11 6.0 11.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2796) WW PF00397.21 CDI88026.1 - 7.9e-07 28.8 0.7 2e-06 27.5 0.5 1.7 1 0 0 1 1 1 1 WW domain PAT1 PF09770.4 CDI88026.1 - 0.063 11.5 33.8 0.07 11.3 23.4 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF1675 PF07897.6 CDI88026.1 - 0.092 12.6 25.4 0.12 12.2 17.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) Ribosomal_60s PF00428.14 CDI88026.1 - 0.21 11.9 2.6 6.4 7.2 0.0 2.4 2 0 0 2 2 2 0 60s Acidic ribosomal protein DUF572 PF04502.8 CDI88026.1 - 0.29 10.3 39.7 0.35 10.0 27.5 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF572) Utp14 PF04615.8 CDI88026.1 - 0.3 9.2 36.3 0.39 8.8 25.2 1.1 1 0 0 1 1 1 0 Utp14 protein DUF605 PF04652.11 CDI88026.1 - 0.39 10.0 32.0 0.51 9.6 22.2 1.2 1 0 0 1 1 1 0 Vta1 like Med15 PF09606.5 CDI88026.1 - 1.3 7.1 42.3 1.5 6.9 29.3 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal BTV_NS2 PF04514.7 CDI88026.1 - 1.7 7.4 28.0 2.2 7.0 19.4 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 DUF2681 PF10883.3 CDI88026.1 - 1.7 8.8 22.7 1.4 9.2 3.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) SOBP PF15279.1 CDI88026.1 - 2 8.7 23.3 2.7 8.3 16.1 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein DNA_pol_viral_N PF00242.12 CDI88026.1 - 3.5 6.5 36.3 4.1 6.3 25.2 1.1 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain Hex_IIIa PF02455.11 CDI88026.1 - 7.3 5.1 24.0 8.2 4.9 16.6 1.1 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) Filo_glycop PF01611.11 CDI88026.1 - 7.6 5.2 19.2 9.5 4.9 13.3 1.3 1 0 0 1 1 1 0 Filovirus glycoprotein Hid1 PF12722.2 CDI88026.1 - 8.3 3.9 35.6 10 3.6 24.7 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein OPT PF03169.10 CDI88027.1 - 0.19 10.0 26.4 0.28 9.5 18.3 1.2 1 0 0 1 1 1 0 OPT oligopeptide transporter protein MIP-T3 PF10243.4 CDI88028.1 - 0.2 10.1 53.6 0.25 9.7 37.2 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Consortin_C PF15281.1 CDI88028.1 - 0.45 10.0 3.6 0.24 10.9 0.3 2.1 2 1 0 2 2 2 0 Consortin C-terminus DUF2232 PF09991.4 CDI88028.1 - 0.51 9.2 9.0 0.023 13.6 2.5 1.4 2 0 0 2 2 2 0 Predicted membrane protein (DUF2232) TRAP_alpha PF03896.11 CDI88028.1 - 5.3 5.9 29.2 0.18 10.7 3.2 3.0 1 1 2 3 3 3 0 Translocon-associated protein (TRAP), alpha subunit DUF3899 PF13038.1 CDI88028.1 - 6 7.0 16.8 0.23 11.6 0.4 3.4 3 1 1 4 4 4 0 Domain of unknown function (DUF3899) ALG3 PF05208.8 CDI88028.1 - 8.3 5.5 7.0 15 4.7 4.6 1.6 1 1 0 1 1 1 0 ALG3 protein PHD_3 PF13922.1 CDI88029.1 - 1 9.6 14.6 2.6 8.3 5.0 2.8 2 0 0 2 2 2 0 PHD domain of transcriptional enhancer, Asx EphA2_TM PF14575.1 CDI88029.1 - 2.4 8.6 6.8 28 5.1 0.2 2.9 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Ribosomal_60s PF00428.14 CDI88030.1 - 0.0096 16.3 9.7 0.011 16.0 6.8 1.2 1 0 0 1 1 1 1 60s Acidic ribosomal protein DUF664 PF04978.7 CDI88030.1 - 0.024 14.8 8.0 0.026 14.7 5.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF664) DUF2946 PF11162.3 CDI88030.1 - 0.097 12.8 6.0 0.1 12.8 4.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2946) EcsC PF12787.2 CDI88030.1 - 0.17 11.2 6.0 0.18 11.1 4.1 1.0 1 0 0 1 1 1 0 EcsC protein family RskA PF10099.4 CDI88030.1 - 0.22 11.2 7.6 0.28 10.9 5.3 1.2 1 0 0 1 1 1 0 Anti-sigma-K factor rskA DUF3292 PF11696.3 CDI88030.1 - 2.2 6.0 5.0 2.6 5.8 3.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) MAT1 PF06391.8 CDI88030.1 - 2.7 7.5 10.1 2.8 7.4 7.0 1.0 1 0 0 1 1 1 0 CDK-activating kinase assembly factor MAT1 Pex16 PF08610.5 CDI88030.1 - 3.7 6.4 7.8 4.1 6.3 5.4 1.0 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) GHBP PF12772.2 CDI88030.1 - 6.3 6.1 13.1 6.8 6.0 9.1 1.0 1 0 0 1 1 1 0 Growth hormone receptor binding DDRGK PF09756.4 CDI88033.1 - 0.28 10.5 43.0 0.022 14.1 19.9 2.3 2 0 0 2 2 2 0 DDRGK domain SPX PF03105.14 CDI88033.1 - 0.49 10.1 25.9 0.69 9.6 18.0 1.2 1 0 0 1 1 1 0 SPX domain Utp14 PF04615.8 CDI88033.1 - 0.67 8.0 35.6 0.92 7.5 24.7 1.1 1 0 0 1 1 1 0 Utp14 protein HCO3_cotransp PF00955.16 CDI88033.1 - 1.9 7.0 15.9 0.12 11.0 6.8 1.7 1 1 1 2 2 2 0 HCO3- transporter family Tim54 PF11711.3 CDI88033.1 - 3.8 6.0 20.1 3.1 6.3 11.2 2.0 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 DUF3108 PF11306.3 CDI88033.1 - 6.6 6.3 6.1 9.2 5.8 4.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3108) SpoIIP PF07454.6 CDI88033.1 - 7.2 5.6 23.2 7.7 5.5 12.2 2.2 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) Peptidase_M56 PF05569.6 CDI88033.1 - 8.5 5.2 16.7 16 4.3 11.5 1.5 1 1 0 1 1 1 0 BlaR1 peptidase M56 DUF2201_N PF13203.1 CDI88033.1 - 9.6 5.2 34.6 0.69 9.0 16.9 2.0 2 0 0 2 2 2 0 Putative metallopeptidase domain DUF4175 PF13779.1 CDI88035.1 - 0.01 13.6 23.0 0.0099 13.6 15.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Pneumo_phosprot PF02478.11 CDI88035.1 - 0.12 11.9 6.0 0.14 11.6 4.1 1.1 1 0 0 1 1 1 0 Pneumovirus phosphoprotein eIF-3_zeta PF05091.7 CDI88035.1 - 0.12 11.0 9.4 0.13 10.8 6.5 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Na_trans_assoc PF06512.8 CDI88035.1 - 0.18 11.7 7.1 0.22 11.4 5.0 1.1 1 0 0 1 1 1 0 Sodium ion transport-associated PAT1 PF09770.4 CDI88035.1 - 0.53 8.4 22.8 0.64 8.1 15.8 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SelP_N PF04592.9 CDI88035.1 - 0.53 9.6 14.3 0.72 9.1 9.9 1.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region AIF_C PF14721.1 CDI88035.1 - 1 9.6 5.9 1.5 9.0 4.1 1.4 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term PBP1_TM PF14812.1 CDI88035.1 - 1.1 9.6 7.5 2.2 8.6 5.2 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Suf PF05843.9 CDI88035.1 - 1.2 8.7 9.5 1.5 8.4 6.6 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Macoilin PF09726.4 CDI88035.1 - 1.4 7.1 11.5 1.6 6.9 8.0 1.1 1 0 0 1 1 1 0 Transmembrane protein DDHD PF02862.12 CDI88035.1 - 1.4 8.6 11.8 1.6 8.4 8.2 1.1 1 0 0 1 1 1 0 DDHD domain Herpes_UL95 PF03038.9 CDI88035.1 - 1.5 7.6 7.5 1.8 7.3 5.2 1.1 1 0 0 1 1 1 0 UL95 family Ycf1 PF05758.7 CDI88035.1 - 1.6 6.3 11.5 1.8 6.2 8.0 1.0 1 0 0 1 1 1 0 Ycf1 Raftlin PF15250.1 CDI88035.1 - 1.7 7.0 11.6 2 6.8 8.0 1.1 1 0 0 1 1 1 0 Raftlin Bud13 PF09736.4 CDI88035.1 - 1.9 8.7 17.5 2.7 8.2 12.1 1.2 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex Ribosomal_60s PF00428.14 CDI88035.1 - 1.9 8.9 13.6 0.088 13.2 2.6 2.4 2 1 0 2 2 2 0 60s Acidic ribosomal protein DUF1764 PF08576.5 CDI88035.1 - 2 9.2 11.7 3.5 8.4 8.1 1.5 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) Serinc PF03348.10 CDI88035.1 - 3.1 6.3 8.7 3.8 6.1 6.0 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) BORG_CEP PF14957.1 CDI88035.1 - 3.1 8.7 8.6 4.8 8.1 6.0 1.3 1 0 0 1 1 1 0 Cdc42 effector Ndc1_Nup PF09531.5 CDI88035.1 - 3.2 6.0 5.5 3.3 5.9 3.8 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Neur_chan_memb PF02932.11 CDI88035.1 - 3.8 7.3 6.5 4.2 7.1 4.5 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Trypan_glycop_C PF10659.4 CDI88035.1 - 4 7.7 9.9 4.1 7.7 5.8 1.8 1 1 1 2 2 1 0 Trypanosome variant surface glycoprotein C-terminal domain Hid1 PF12722.2 CDI88035.1 - 4.3 4.8 13.8 4.8 4.7 9.6 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein WBS_methylT PF12589.3 CDI88035.1 - 5.9 7.4 14.2 9.4 6.8 9.8 1.3 1 0 0 1 1 1 0 Methyltransferase involved in Williams-Beuren syndrome Folate_carrier PF01770.13 CDI88035.1 - 7.1 5.0 6.2 9 4.6 4.3 1.2 1 0 0 1 1 1 0 Reduced folate carrier SprA-related PF12118.3 CDI88036.1 - 0.00064 19.1 35.3 0.00082 18.7 24.5 1.1 1 0 0 1 1 1 1 SprA-related family Utp14 PF04615.8 CDI88036.1 - 0.66 8.0 26.2 0.74 7.9 18.2 1.0 1 0 0 1 1 1 0 Utp14 protein DUF2413 PF10310.4 CDI88036.1 - 2.5 6.8 26.5 3.2 6.4 18.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) TFIIA PF03153.8 CDI88036.1 - 3.1 7.5 28.2 3.9 7.2 19.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SOBP PF15279.1 CDI88036.1 - 4.1 7.7 25.6 4.7 7.4 17.7 1.0 1 0 0 1 1 1 0 Sine oculis-binding protein UPF0542 PF15086.1 CDI88036.1 - 4.8 6.9 8.7 0.22 11.2 1.7 2.1 2 1 0 2 2 2 0 Uncharacterised protein family UPF0542 RAB3GAP2_N PF14655.1 CDI88036.1 - 9.3 5.1 17.2 0.097 11.6 5.7 1.7 1 1 1 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Plasmodium_Vir PF05795.6 CDI88038.1 - 0.17 11.0 2.8 0.17 11.0 2.0 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein DUF3439 PF11921.3 CDI88038.1 - 0.47 10.2 18.0 0.2 11.4 10.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) PAT1 PF09770.4 CDI88038.1 - 1 7.4 25.0 1.2 7.3 17.3 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 AMP-binding PF00501.23 CDI88038.1 - 1.3 7.2 6.9 1.6 7.0 4.8 1.1 1 0 0 1 1 1 0 AMP-binding enzyme RCR PF12273.3 CDI88038.1 - 4.5 7.8 15.2 6.2 7.3 10.6 1.3 1 0 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red Macoilin PF09726.4 CDI88038.1 - 5.4 5.1 18.1 7.2 4.7 12.6 1.2 1 0 0 1 1 1 0 Transmembrane protein MMR1 PF08505.5 CDI88038.1 - 6.3 6.7 21.3 7.7 6.4 14.8 1.1 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein DUF2217 PF10265.4 CDI88038.1 - 7.2 5.2 8.2 8.3 5.0 5.7 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) TMEM51 PF15345.1 CDI88038.1 - 9.7 5.8 15.8 13 5.4 11.0 1.2 1 0 0 1 1 1 0 Transmembrane protein 51 PAT1 PF09770.4 CDI88039.1 - 0.0044 15.3 25.6 0.0047 15.2 17.8 1.1 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 Activator_LAG-3 PF11498.3 CDI88039.1 - 0.0085 14.8 52.8 0.016 13.9 36.6 1.4 1 0 0 1 1 1 1 Transcriptional activator LAG-3 V_ATPase_I PF01496.14 CDI88039.1 - 1.4 6.6 7.1 1.7 6.4 4.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Herpes_UL87 PF03043.9 CDI88039.1 - 1.6 7.0 6.6 1.9 6.8 4.6 1.1 1 0 0 1 1 1 0 Herpesvirus UL87 family HlyD_2 PF12700.2 CDI88039.1 - 2.3 7.2 8.7 2.7 7.0 6.0 1.1 1 0 0 1 1 1 0 HlyD family secretion protein DUF1510 PF07423.6 CDI88040.1 - 1.5e-05 24.4 21.1 1.8e-05 24.2 14.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) TRAP_alpha PF03896.11 CDI88040.1 - 6.6e-05 22.0 10.6 6.6e-05 22.0 7.4 2.0 1 1 1 2 2 2 1 Translocon-associated protein (TRAP), alpha subunit SpoIIIAH PF12685.2 CDI88040.1 - 0.00018 21.0 6.4 0.00024 20.6 4.4 1.2 1 0 0 1 1 1 1 SpoIIIAH-like protein Ycf1 PF05758.7 CDI88040.1 - 0.0071 14.1 16.0 0.0077 14.0 11.1 1.1 1 0 0 1 1 1 1 Ycf1 DUF4366 PF14283.1 CDI88040.1 - 0.08 12.3 26.9 1.8e+02 1.4 18.5 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4366) SAPS PF04499.10 CDI88040.1 - 0.29 9.7 13.8 0.31 9.6 9.6 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Conotoxin PF02950.12 CDI88040.1 - 0.43 11.4 0.1 0.43 11.4 0.1 2.5 1 1 1 2 2 2 0 Conotoxin MIP-T3 PF10243.4 CDI88040.1 - 7.1 4.9 40.5 8 4.7 28.0 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 FA_desaturase PF00487.19 CDI88041.1 - 0.013 14.9 0.5 0.014 14.8 0.3 1.2 1 0 0 1 1 1 0 Fatty acid desaturase DUF2207 PF09972.4 CDI88041.1 - 0.028 13.0 6.8 0.034 12.7 4.7 1.3 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) PAT1 PF09770.4 CDI88041.1 - 0.046 11.9 37.4 0.046 11.9 25.9 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TRP PF06011.7 CDI88041.1 - 0.089 11.3 7.5 0.099 11.2 5.2 1.0 1 0 0 1 1 1 0 Transient receptor potential (TRP) ion channel DUF1985 PF09331.6 CDI88041.1 - 0.21 11.3 2.4 0.31 10.8 1.3 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF1985) Reticulon PF02453.12 CDI88041.1 - 0.46 10.0 7.6 0.61 9.6 5.3 1.3 1 0 0 1 1 1 0 Reticulon DUF4400 PF14348.1 CDI88041.1 - 0.5 9.7 15.7 0.59 9.4 10.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4400) Pex24p PF06398.6 CDI88041.1 - 0.71 8.6 10.4 0.87 8.3 7.2 1.1 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin TraG_N PF07916.6 CDI88041.1 - 1.2 7.4 19.9 1.6 7.1 13.8 1.0 1 0 0 1 1 1 0 TraG-like protein, N-terminal region DUF912 PF06024.7 CDI88041.1 - 1.4 8.9 17.1 35 4.5 11.8 2.3 1 1 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) VIT1 PF01988.14 CDI88041.1 - 3 7.2 5.7 4 6.8 4.0 1.2 1 0 0 1 1 1 0 VIT family SID-1_RNA_chan PF13965.1 CDI88041.1 - 4.3 5.3 8.5 4.6 5.2 5.9 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 PMT_C PF11647.3 CDI88041.1 - 7.3 6.2 14.3 4.9 6.8 3.2 2.8 1 1 1 2 2 2 0 C-terminal region of Pasteurella multocida toxin residues 569-1285 CD20 PF04103.10 CDI88041.1 - 7.4 6.4 10.0 20 5.1 7.0 1.8 1 1 0 1 1 1 0 CD20-like family Pex14_N PF04695.8 CDI88043.1 - 0.024 14.6 39.5 0.077 13.0 14.1 2.2 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region ABC2_membrane_2 PF12679.2 CDI88043.1 - 0.16 10.8 6.6 0.012 14.5 1.0 1.6 2 0 0 2 2 2 0 ABC-2 family transporter protein hGDE_central PF14702.1 CDI88043.1 - 0.29 10.2 6.8 0.17 11.0 3.6 1.4 1 1 0 1 1 1 0 central domain of human glycogen debranching enzyme Baculo_PP31 PF05311.6 CDI88043.1 - 1.6 7.9 32.5 0.47 9.6 6.1 2.1 2 0 0 2 2 2 0 Baculovirus 33KDa late protein (PP31) FAM176 PF14851.1 CDI88043.1 - 2.5 7.7 14.6 0.16 11.6 2.2 2.2 2 0 0 2 2 2 0 FAM176 family Eapp_C PF10238.4 CDI88043.1 - 2.8 7.8 15.6 2.6 7.9 4.7 2.3 2 0 0 2 2 2 0 E2F-associated phosphoprotein eIF_4EBP PF05456.6 CDI88043.1 - 2.9 7.6 21.1 2.1 8.0 3.3 2.3 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) PH_4 PF15404.1 CDI88043.1 - 9.5 5.6 20.4 0.71 9.3 5.5 2.2 2 0 0 2 2 2 0 Pleckstrin homology domain Utp14 PF04615.8 CDI88044.1 - 8.9 4.3 38.6 11 4.0 26.7 1.0 1 0 0 1 1 1 0 Utp14 protein RVT_1 PF00078.22 CDI88045.1 - 2.1e-12 46.8 0.1 8.3e-07 28.5 0.0 2.2 1 1 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) SR-25 PF10500.4 CDI88047.1 - 0.00036 20.0 3.3 0.00039 19.9 2.3 1.0 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein DUF123 PF01986.11 CDI88047.1 - 0.034 14.2 0.8 0.04 14.0 0.6 1.2 1 0 0 1 1 1 0 Domain of unknown function DUF123 zf-RVT PF13966.1 CDI88047.1 - 0.049 13.9 0.2 0.055 13.7 0.2 1.0 1 0 0 1 1 1 0 zinc-binding in reverse transcriptase Enkurin PF13864.1 CDI88047.1 - 0.16 12.2 7.0 0.18 12.0 4.8 1.0 1 0 0 1 1 1 0 Calmodulin-binding Mgr1 PF08602.5 CDI88047.1 - 0.71 8.8 4.4 0.81 8.6 3.1 1.0 1 0 0 1 1 1 0 Mgr1-like, i-AAA protease complex subunit FAD-SLDH PF12318.3 CDI88047.1 - 1.5 8.4 6.3 1.5 8.4 4.4 1.1 1 0 0 1 1 1 0 Membrane bound FAD containing D-sorbitol dehydrogenase CDK5_activator PF03261.10 CDI88047.1 - 1.7 7.9 8.9 1.9 7.7 6.2 1.0 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein RRP14 PF15459.1 CDI88047.1 - 1.8 8.6 8.2 6 7.0 2.2 2.1 2 0 0 2 2 2 0 60S ribosome biogenesis protein Rrp14 Serinc PF03348.10 CDI88047.1 - 2.7 6.6 6.7 2.9 6.4 4.6 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) DUF243 PF03103.12 CDI88047.1 - 2.9 8.0 8.8 3.7 7.7 6.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF243) UPF0560 PF10577.4 CDI88047.1 - 3.4 5.8 12.0 3.4 5.7 8.3 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Med15 PF09606.5 CDI88047.1 - 4.5 5.3 21.1 4.8 5.2 14.6 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF4557 PF15101.1 CDI88047.1 - 6.7 6.4 10.6 7.1 6.4 7.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) AAA_11 PF13086.1 CDI88050.1 - 0.00059 19.4 2.0 0.00068 19.2 1.4 1.1 1 0 0 1 1 1 1 AAA domain PhageMin_Tail PF10145.4 CDI88050.1 - 0.22 11.1 6.9 0.035 13.7 2.4 1.4 1 1 0 1 1 1 0 Phage-related minor tail protein Cyclin_C PF02984.14 CDI88050.1 - 0.31 10.9 4.8 0.57 10.1 3.3 1.4 1 0 0 1 1 1 0 Cyclin, C-terminal domain DUF4407 PF14362.1 CDI88050.1 - 2.3 7.1 14.4 2.8 6.8 10.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) BAF1_ABF1 PF04684.8 CDI88050.1 - 2.4 6.9 25.2 3.2 6.4 17.5 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Folliculin PF11704.3 CDI88050.1 - 3.5 7.1 11.6 1.8 8.0 6.7 1.5 1 1 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport Activator_LAG-3 PF11498.3 CDI88051.1 - 0.48 9.1 13.1 0.99 8.0 9.1 1.5 1 0 0 1 1 1 0 Transcriptional activator LAG-3 TAF8_C PF10406.4 CDI88053.1 - 1.3e-07 31.5 2.2 1.3e-07 31.5 1.6 3.0 3 0 0 3 3 3 1 Transcription factor TFIID complex subunit 8 C-term Actin PF00022.14 CDI88053.1 - 0.067 11.5 1.4 0.1 10.9 0.7 1.5 1 1 0 1 1 1 0 Actin Ribosomal_60s PF00428.14 CDI88053.1 - 0.58 10.5 10.9 1.5 9.3 7.6 1.6 1 0 0 1 1 1 0 60s Acidic ribosomal protein TRAPPC10 PF12584.3 CDI88053.1 - 1.3 8.4 9.6 2.5 7.5 2.8 2.3 2 0 0 2 2 2 0 Trafficking protein particle complex subunit 10, TRAPPC10 DUF2407_C PF13373.1 CDI88053.1 - 2.2 8.1 15.2 0.062 13.2 4.9 2.2 2 1 0 2 2 2 0 DUF2407 C-terminal domain Baculo_PP31 PF05311.6 CDI88053.1 - 9.4 5.4 14.2 1.8 7.7 5.8 2.0 2 0 0 2 2 2 0 Baculovirus 33KDa late protein (PP31) Pro-rich PF15240.1 CDI88054.1 - 0.012 15.7 13.3 0.016 15.2 9.2 1.2 1 0 0 1 1 1 0 Proline-rich DUF4570 PF15134.1 CDI88056.1 - 0.023 14.5 3.4 0.023 14.5 2.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4570) AMMECR1 PF01871.12 CDI88056.1 - 0.052 12.6 0.5 0.068 12.2 0.0 1.4 2 0 0 2 2 2 0 AMMECR1 FHIPEP PF00771.15 CDI88056.1 - 0.1 10.9 3.2 0.11 10.7 2.2 1.1 1 0 0 1 1 1 0 FHIPEP family DUF4175 PF13779.1 CDI88056.1 - 0.21 9.2 21.1 0.26 8.9 14.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) DUF4407 PF14362.1 CDI88056.1 - 0.51 9.2 9.4 0.67 8.8 6.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) eIF-3_zeta PF05091.7 CDI88056.1 - 0.57 8.7 5.5 0.63 8.5 3.8 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) TFIIA PF03153.8 CDI88056.1 - 0.59 9.9 13.5 0.65 9.8 9.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF3154 PF11351.3 CDI88056.1 - 1.1 9.0 10.8 0.21 11.3 2.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3154) DUF2489 PF10675.4 CDI88056.1 - 2.5 7.7 17.3 0.3 10.7 3.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2489) DUF3138 PF11336.3 CDI88056.1 - 4.7 5.2 6.4 6.2 4.8 4.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) JAB PF01398.16 CDI88056.1 - 5.2 6.8 7.4 0.46 10.2 0.9 1.9 1 1 0 2 2 2 0 JAB1/Mov34/MPN/PAD-1 ubiquitin protease PHD_3 PF13922.1 CDI88056.1 - 5.5 7.3 18.4 0.89 9.8 3.3 2.3 2 0 0 2 2 2 0 PHD domain of transcriptional enhancer, Asx Phostensin_N PF13916.1 CDI88056.1 - 5.5 7.0 19.5 6.4 6.8 5.0 2.6 2 0 0 2 2 2 0 PP1-regulatory protein, Phostensin N-terminal U3_snoRNA_assoc PF08297.6 CDI88056.1 - 5.8 7.2 10.0 0.11 12.7 1.2 1.9 2 0 0 2 2 2 0 U3 snoRNA associated FimP PF09766.4 CDI88056.1 - 6.3 5.7 17.6 0.31 10.0 3.4 2.1 2 0 0 2 2 2 0 Fms-interacting protein DUF4557 PF15101.1 CDI88056.1 - 7.3 6.3 15.1 0.066 13.0 1.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4557) APC_CDC26 PF10471.4 CDI88056.1 - 8.3 7.2 25.2 8.4 7.2 7.5 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit 1 Trigger_C PF05698.9 CDI88057.1 - 7.9e-07 29.0 9.9 0.00012 21.9 4.0 2.0 1 1 1 2 2 2 2 Bacterial trigger factor protein (TF) C-terminus Fer4_18 PF13746.1 CDI88057.1 - 0.052 13.9 1.4 0.13 12.6 0.9 1.9 1 1 0 1 1 1 0 4Fe-4S dicluster domain CcdA PF07362.7 CDI88057.1 - 0.21 11.4 4.8 0.36 10.7 2.9 1.9 1 1 0 1 1 1 0 Post-segregation antitoxin CcdA DUF2390 PF09523.5 CDI88057.1 - 0.23 11.6 4.7 3.9 7.7 0.2 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF2390) Fer4_16 PF13484.1 CDI88057.1 - 0.27 11.9 4.7 1.4 9.7 3.3 2.1 1 1 0 1 1 1 0 4Fe-4S double cluster binding domain DUF1115 PF06544.7 CDI88057.1 - 0.37 10.4 7.6 0.54 9.9 5.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1115) VSG_B PF13206.1 CDI88057.1 - 0.48 9.4 13.6 0.57 9.2 9.4 1.0 1 0 0 1 1 1 0 Trypanosomal VSG domain zf-met PF12874.2 CDI88058.1 - 4.2e-07 29.9 1.5 8.4e-07 28.9 1.1 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type PPR_2 PF13041.1 CDI88059.1 - 4.7e-11 42.4 0.1 4.1e-06 26.6 0.0 4.7 3 1 1 4 4 4 2 PPR repeat family PPR_3 PF13812.1 CDI88059.1 - 9e-09 34.9 25.7 0.25 11.7 0.0 9.5 9 0 0 9 9 9 4 Pentatricopeptide repeat domain PPR PF01535.15 CDI88059.1 - 1.1e-08 34.5 6.3 0.028 14.3 0.0 6.4 7 0 0 7 7 7 2 PPR repeat TPR_3 PF07720.7 CDI88059.1 - 0.097 12.4 2.4 0.39 10.5 0.1 3.2 2 0 0 2 2 2 0 Tetratricopeptide repeat HEAT PF02985.17 CDI88060.1 - 0.015 15.3 0.0 0.048 13.7 0.0 1.9 1 0 0 1 1 1 0 HEAT repeat Androgen_recep PF02166.11 CDI88060.1 - 0.031 13.1 6.2 0.039 12.8 4.3 1.1 1 0 0 1 1 1 0 Androgen receptor Pneumo_att_G PF05539.6 CDI88060.1 - 0.041 13.2 2.2 0.045 13.1 1.5 1.0 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G ComFB PF10719.4 CDI88060.1 - 0.17 11.6 2.2 8.4 6.2 0.4 2.1 2 0 0 2 2 2 0 Late competence development protein ComFB DUF3115 PF11312.3 CDI88061.1 - 0.01 14.7 0.0 0.013 14.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3115) Spt20 PF12090.3 CDI88061.1 - 0.16 11.3 2.0 0.17 11.2 0.1 1.8 2 0 0 2 2 2 0 Spt20 family dsDNA_bind PF01984.15 CDI88061.1 - 1 9.3 11.0 0.25 11.3 1.6 2.2 2 0 0 2 2 2 0 Double-stranded DNA-binding domain APC_CDC26 PF10471.4 CDI88061.1 - 1.4 9.6 11.8 8 7.2 6.0 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit 1 PHD_3 PF13922.1 CDI88061.1 - 9 6.6 7.3 1.4 9.1 1.4 2.0 2 0 0 2 2 2 0 PHD domain of transcriptional enhancer, Asx DUF2572 PF10833.3 CDI88062.1 - 0.035 13.5 5.5 0.049 13.0 3.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2572) IncA PF04156.9 CDI88062.1 - 0.059 12.9 18.0 0.065 12.8 12.5 1.0 1 0 0 1 1 1 0 IncA protein RPA_interact_N PF14766.1 CDI88062.1 - 0.07 12.6 0.1 0.16 11.4 0.1 1.6 1 0 0 1 1 1 0 Replication protein A interacting N-terminal GNT-I PF03071.10 CDI88062.1 - 0.091 11.2 2.0 0.1 11.1 1.4 1.0 1 0 0 1 1 1 0 GNT-I family DUF4254 PF14063.1 CDI88062.1 - 0.12 11.9 6.6 0.15 11.7 4.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4254) DUF123 PF01986.11 CDI88062.1 - 0.14 12.3 0.4 0.18 11.9 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function DUF123 FCH PF00611.18 CDI88062.1 - 0.19 11.9 6.8 0.26 11.4 4.7 1.1 1 0 0 1 1 1 0 Fes/CIP4, and EFC/F-BAR homology domain DUF3037 PF11236.3 CDI88062.1 - 0.2 11.7 4.0 0.42 10.6 2.7 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3037) DUF3450 PF11932.3 CDI88062.1 - 0.21 10.7 14.8 0.38 9.9 10.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) DUF3426 PF11906.3 CDI88062.1 - 0.32 10.6 7.2 0.3 10.7 3.9 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3426) DUF3708 PF12501.3 CDI88062.1 - 1.1 9.0 4.7 1.6 8.5 3.2 1.3 1 0 0 1 1 1 0 Phosphate ATP-binding cassette transporter Atg14 PF10186.4 CDI88062.1 - 2.5 6.9 11.5 2.7 6.8 7.9 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 LPP PF04728.8 CDI88062.1 - 6 6.7 7.8 0.34 10.7 1.6 1.8 1 1 1 2 2 2 0 Lipoprotein leucine-zipper Phage_GPO PF05929.6 CDI88062.1 - 6.1 6.0 8.5 7.3 5.7 5.9 1.1 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF3365 PF11845.3 CDI88062.1 - 8.9 6.1 8.0 20 4.9 5.5 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3365) Spt20 PF12090.3 CDI88063.1 - 0.00045 19.6 0.3 0.00045 19.6 0.2 1.1 1 0 0 1 1 1 1 Spt20 family Suf PF05843.9 CDI88063.1 - 0.052 13.2 3.8 0.052 13.2 2.6 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Protamine_P2 PF00841.14 CDI88063.1 - 0.11 12.9 9.2 0.18 12.3 6.4 1.2 1 0 0 1 1 1 0 Sperm histone P2 zf-DHHC PF01529.15 CDI88063.1 - 0.14 11.5 0.1 0.13 11.6 0.1 1.1 1 0 0 1 1 1 0 DHHC palmitoyltransferase Peptidase_S49_N PF08496.5 CDI88063.1 - 0.24 11.2 3.8 0.39 10.4 2.6 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal PAT1 PF09770.4 CDI88063.1 - 0.25 9.5 15.9 0.27 9.4 11.0 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 FimP PF09766.4 CDI88063.1 - 0.29 10.1 10.6 0.37 9.8 7.3 1.1 1 0 0 1 1 1 0 Fms-interacting protein Serinc PF03348.10 CDI88063.1 - 0.42 9.2 1.5 0.46 9.1 1.1 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) MSP1_C PF07462.6 CDI88063.1 - 1.6 7.0 5.8 1.9 6.8 4.0 1.2 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Activator_LAG-3 PF11498.3 CDI88063.1 - 4.3 5.9 23.7 5.9 5.5 16.5 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 UPF0560 PF10577.4 CDI88063.1 - 4.4 5.4 9.4 5.4 5.1 6.5 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 EURL PF06937.6 CDI88065.1 - 0.058 12.8 11.4 0.065 12.6 7.9 1.0 1 0 0 1 1 1 0 EURL protein Borrelia_P83 PF05262.6 CDI88065.1 - 0.093 10.9 19.8 0.1 10.8 13.7 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein MotA_ExbB PF01618.11 CDI88065.1 - 0.13 11.9 6.6 0.13 11.8 4.1 1.4 1 1 0 1 1 1 0 MotA/TolQ/ExbB proton channel family Pex14_N PF04695.8 CDI88065.1 - 0.18 11.8 9.2 0.2 11.6 6.4 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF1943 PF09172.6 CDI88065.1 - 0.26 10.1 8.3 0.27 10.0 5.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1943) DUF3337 PF11816.3 CDI88065.1 - 0.35 10.2 5.8 0.36 10.1 4.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3337) FAD-oxidase_C PF02913.14 CDI88065.1 - 0.37 10.0 2.6 0.49 9.6 1.8 1.2 1 0 0 1 1 1 0 FAD linked oxidases, C-terminal domain Dynamin_N PF00350.18 CDI88065.1 - 0.39 10.5 3.5 0.45 10.3 2.4 1.1 1 0 0 1 1 1 0 Dynamin family DUF3584 PF12128.3 CDI88065.1 - 0.51 7.6 21.3 0.58 7.4 14.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) CDC45 PF02724.9 CDI88065.1 - 0.52 8.2 10.5 0.58 8.1 7.3 1.0 1 0 0 1 1 1 0 CDC45-like protein eIF3_subunit PF08597.5 CDI88065.1 - 0.56 9.7 15.9 0.63 9.5 11.0 1.1 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit RED_N PF07808.8 CDI88065.1 - 0.66 9.1 18.1 0.78 8.9 12.5 1.0 1 0 0 1 1 1 0 RED-like protein N-terminal region Raptor_N PF14538.1 CDI88065.1 - 0.67 9.7 4.1 0.75 9.6 2.9 1.1 1 0 0 1 1 1 0 Raptor N-terminal CASPase like domain Gastrin PF00918.12 CDI88065.1 - 0.71 10.7 10.4 0.92 10.3 7.2 1.3 1 0 0 1 1 1 0 Gastrin/cholecystokinin family DUF853 PF05872.7 CDI88065.1 - 0.98 7.6 8.7 1 7.6 6.0 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) DUF2072 PF09845.4 CDI88065.1 - 1.1 9.2 5.8 1.4 8.8 4.0 1.3 1 0 0 1 1 1 0 Zn-ribbon containing protein (DUF2072) FAM60A PF15396.1 CDI88065.1 - 1.1 8.9 6.0 1.2 8.8 4.2 1.1 1 0 0 1 1 1 0 Protein Family FAM60A EIIBC-GUT_N PF03612.9 CDI88065.1 - 1.3 8.6 5.8 1.3 8.6 4.0 1.2 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus FRQ PF09421.5 CDI88065.1 - 1.4 6.6 7.5 1.5 6.4 5.2 1.0 1 0 0 1 1 1 0 Frequency clock protein Vfa1 PF08432.5 CDI88065.1 - 1.4 8.8 11.7 1.7 8.6 8.1 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 GBP_C PF02841.9 CDI88065.1 - 1.5 7.9 21.4 1.7 7.7 14.8 1.0 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain MRC1 PF09444.5 CDI88065.1 - 1.5 9.1 12.4 3.3 8.0 8.6 1.6 1 1 0 1 1 1 0 MRC1-like domain DUF775 PF05603.7 CDI88065.1 - 1.6 8.2 10.0 1.8 8.0 6.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF775) Ctr PF04145.10 CDI88065.1 - 1.7 8.7 5.4 2 8.4 3.7 1.1 1 0 0 1 1 1 0 Ctr copper transporter family ApoO PF09769.4 CDI88065.1 - 1.8 8.2 5.2 2 8.0 3.6 1.2 1 0 0 1 1 1 0 Apolipoprotein O SprA-related PF12118.3 CDI88065.1 - 2 7.6 22.9 2.4 7.4 15.9 1.1 1 0 0 1 1 1 0 SprA-related family Dala_Dala_lig_N PF01820.16 CDI88065.1 - 2 8.7 5.8 2.6 8.3 4.0 1.2 1 0 0 1 1 1 0 D-ala D-ala ligase N-terminus Exonuc_VII_L PF02601.10 CDI88065.1 - 2.2 7.4 12.8 2.5 7.1 8.8 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF4175 PF13779.1 CDI88065.1 - 2.4 5.7 29.3 2.7 5.5 20.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Ycf1 PF05758.7 CDI88065.1 - 2.5 5.7 13.2 2.7 5.6 9.1 1.0 1 0 0 1 1 1 0 Ycf1 DUF3499 PF12005.3 CDI88065.1 - 2.7 8.1 5.2 3.4 7.8 3.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3499) Presenilin PF01080.12 CDI88065.1 - 3 6.5 5.2 3.2 6.4 3.6 1.0 1 0 0 1 1 1 0 Presenilin Phosducin PF02114.11 CDI88065.1 - 3.2 6.4 13.7 3.7 6.2 9.5 1.0 1 0 0 1 1 1 0 Phosducin DDHD PF02862.12 CDI88065.1 - 3.2 7.4 9.0 3.7 7.2 6.2 1.1 1 0 0 1 1 1 0 DDHD domain DOR PF14839.1 CDI88065.1 - 3.7 7.2 18.5 4.7 6.8 12.9 1.1 1 0 0 1 1 1 0 DOR family Band_3_cyto PF07565.8 CDI88065.1 - 4 6.8 9.0 4.7 6.6 6.2 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain HemX PF04375.9 CDI88065.1 - 4.3 5.8 21.1 5.9 5.3 14.6 1.3 1 0 0 1 1 1 0 HemX APG6 PF04111.7 CDI88065.1 - 4.8 6.1 19.3 5.7 5.8 13.4 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 RNA_pol_Rpb1_5 PF04998.12 CDI88065.1 - 5 6.3 8.1 5.4 6.1 5.6 1.0 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 HlyD_2 PF12700.2 CDI88065.1 - 5.9 5.9 14.1 7.4 5.6 9.8 1.2 1 0 0 1 1 1 0 HlyD family secretion protein DUF4407 PF14362.1 CDI88065.1 - 6.9 5.5 18.1 7.9 5.3 12.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF1764 PF08576.5 CDI88065.1 - 8.2 7.2 12.7 10 6.9 8.8 1.2 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) Ycf1 PF05758.7 CDI88066.1 - 0.066 10.9 9.6 0.066 10.9 6.6 1.0 1 0 0 1 1 1 0 Ycf1 PLRV_ORF5 PF01690.12 CDI88066.1 - 0.34 9.9 13.4 0.39 9.8 9.3 1.0 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Macoilin PF09726.4 CDI88066.1 - 0.34 9.1 13.1 0.41 8.8 9.1 1.1 1 0 0 1 1 1 0 Transmembrane protein HGTP_anticodon2 PF12745.2 CDI88066.1 - 1.2 8.2 10.9 1.5 7.8 7.6 1.1 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs Mmp37 PF09139.6 CDI88066.1 - 3.4 6.6 8.9 4.3 6.2 6.2 1.1 1 0 0 1 1 1 0 Mitochondrial matrix Mmp37 Asp-B-Hydro_N PF05279.6 CDI88066.1 - 6.6 6.5 12.3 7.9 6.2 8.5 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Neur_chan_memb PF02932.11 CDI88066.1 - 8.5 6.1 7.4 11 5.8 5.1 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Laminin_G_3 PF13385.1 CDI88067.1 - 3.6e-06 27.2 0.0 2.8e-05 24.3 0.0 2.0 1 1 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily SpvB PF03534.8 CDI88067.1 - 0.83 8.6 7.3 1.4 7.8 5.0 1.3 1 0 0 1 1 1 0 Salmonella virulence plasmid 65kDa B protein AAA_23 PF13476.1 CDI88068.1 - 0.16 12.3 10.3 0.2 11.9 7.1 1.2 1 0 0 1 1 1 0 AAA domain Suf PF05843.9 CDI88068.1 - 0.28 10.8 11.5 0.41 10.3 8.0 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) PAT1 PF09770.4 CDI88068.1 - 0.29 9.3 25.4 0.38 8.9 17.6 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 CARM1 PF11531.3 CDI88068.1 - 0.34 10.6 0.0 0.34 10.6 0.0 2.1 2 0 0 2 2 2 0 Coactivator-associated arginine methyltransferase 1 N terminal Spt20 PF12090.3 CDI88068.1 - 0.36 10.1 10.8 0.53 9.6 7.5 1.3 1 0 0 1 1 1 0 Spt20 family RR_TM4-6 PF06459.7 CDI88068.1 - 0.82 9.5 9.6 1.3 8.8 6.7 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Adeno_VII PF03228.9 CDI88068.1 - 2 9.0 6.7 4 8.0 4.6 1.4 1 0 0 1 1 1 0 Adenoviral core protein VII OATP PF03137.15 CDI88068.1 - 4.7 5.1 6.6 6 4.7 4.6 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Kei1 PF08552.6 CDI88068.1 - 7.3 6.2 7.6 12 5.4 5.3 1.2 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 DDE_Tnp_Tn3 PF01526.12 CDI88069.1 - 0.0084 14.7 8.3 0.012 14.2 5.7 1.2 1 0 0 1 1 1 1 Tn3 transposase DDE domain Bud13 PF09736.4 CDI88069.1 - 0.093 12.9 12.0 0.15 12.3 8.3 1.4 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex AKAP28 PF14469.1 CDI88069.1 - 0.1 12.1 2.0 0.18 11.4 1.4 1.3 1 0 0 1 1 1 0 28 kDa A-kinase anchor UPF0560 PF10577.4 CDI88069.1 - 0.15 10.2 16.1 0.19 9.9 11.2 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 DUF966 PF06136.8 CDI88069.1 - 0.24 10.8 11.8 0.29 10.5 8.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Otopetrin PF03189.8 CDI88069.1 - 0.49 9.3 3.0 0.53 9.2 2.1 1.1 1 0 0 1 1 1 0 Otopetrin Pex16 PF08610.5 CDI88069.1 - 0.5 9.3 7.5 0.57 9.1 5.2 1.1 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) Ycf1 PF05758.7 CDI88069.1 - 0.77 7.3 6.5 0.79 7.3 4.5 1.0 1 0 0 1 1 1 0 Ycf1 Shadoo PF14999.1 CDI88069.1 - 1.4 8.7 18.7 2.8 7.7 1.3 2.2 2 0 0 2 2 2 0 Shadow of prion protein, neuroprotective Hid1 PF12722.2 CDI88069.1 - 1.7 6.2 9.7 1.9 6.0 6.7 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Ndc1_Nup PF09531.5 CDI88069.1 - 1.8 6.9 10.0 1.9 6.7 7.0 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup ABC2_membrane_2 PF12679.2 CDI88069.1 - 2.2 7.0 4.4 3.1 6.5 3.0 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein AAA_13 PF13166.1 CDI88069.1 - 2.4 6.5 11.7 2.7 6.3 8.1 1.0 1 0 0 1 1 1 0 AAA domain Sec62 PF03839.11 CDI88069.1 - 2.5 7.4 6.7 3.5 6.9 4.7 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 Ribosomal_60s PF00428.14 CDI88069.1 - 3.7 8.0 33.2 0.19 12.1 3.4 2.4 2 1 0 2 2 2 0 60s Acidic ribosomal protein PAT1 PF09770.4 CDI88069.1 - 7.5 4.6 38.4 8.4 4.4 26.6 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SR-25 PF10500.4 CDI88070.1 - 0.04 13.3 18.5 0.053 12.9 12.8 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein ARGLU PF15346.1 CDI88070.1 - 0.14 11.9 12.4 0.16 11.7 8.6 1.1 1 0 0 1 1 1 0 Arginine and glutamate-rich 1 Aminotran_1_2 PF00155.16 CDI88070.1 - 0.27 10.1 5.6 0.33 9.8 3.9 1.1 1 0 0 1 1 1 0 Aminotransferase class I and II Dsh_C PF12316.3 CDI88070.1 - 0.5 10.4 18.5 0.57 10.2 12.8 1.0 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal Zip PF02535.17 CDI88070.1 - 0.7 8.8 18.7 0.76 8.7 13.0 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Peptidase_S30 PF01577.11 CDI88070.1 - 1 8.7 13.6 1.2 8.5 9.4 1.1 1 0 0 1 1 1 0 Potyvirus P1 protease Nop53 PF07767.6 CDI88070.1 - 1 8.2 17.0 1.2 8.0 11.8 1.0 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) AAA_2 PF07724.9 CDI88070.1 - 1.4 8.8 10.1 4.5 7.1 7.0 1.8 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) Paramyxo_C PF01692.13 CDI88070.1 - 1.9 8.0 18.1 2.5 7.6 12.5 1.3 1 0 0 1 1 1 0 Paramyxovirus non-structural protein c Dicty_REP PF05086.7 CDI88070.1 - 2.4 5.7 21.3 2.8 5.5 14.8 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Spore_YhcN_YlaJ PF09580.5 CDI88070.1 - 2.6 8.1 18.3 3.4 7.7 12.7 1.1 1 0 0 1 1 1 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) Herpes_TAF50 PF03326.8 CDI88070.1 - 3.5 6.4 23.4 3.9 6.3 16.2 1.0 1 0 0 1 1 1 0 Herpesvirus transcription activation factor (transactivator) DUF1779 PF08680.5 CDI88070.1 - 4.1 7.2 13.0 4.5 7.0 9.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1779) SprA-related PF12118.3 CDI88070.1 - 4.3 6.5 35.2 5.1 6.3 24.4 1.1 1 0 0 1 1 1 0 SprA-related family Rtf2 PF04641.7 CDI88070.1 - 4.6 6.3 18.4 5.6 6.0 12.8 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger CKAP2_C PF15297.1 CDI88070.1 - 5.6 5.6 16.6 6.4 5.4 11.5 1.2 1 0 0 1 1 1 0 Cytoskeleton-associated protein 2 C-terminus FAM60A PF15396.1 CDI88070.1 - 5.7 6.6 17.6 6.6 6.4 12.2 1.1 1 0 0 1 1 1 0 Protein Family FAM60A BPL_N PF09825.4 CDI88070.1 - 6.3 5.4 11.2 6.7 5.3 7.8 1.0 1 0 0 1 1 1 0 Biotin-protein ligase, N terminal Presenilin PF01080.12 CDI88070.1 - 6.9 5.3 16.3 8.1 5.1 11.3 1.0 1 0 0 1 1 1 0 Presenilin DUF4569 PF15133.1 CDI88070.1 - 6.9 5.9 19.7 7.6 5.8 13.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4569) Macoilin PF09726.4 CDI88070.1 - 7.3 4.7 22.1 8.4 4.5 15.3 1.1 1 0 0 1 1 1 0 Transmembrane protein AAA_23 PF13476.1 CDI88070.1 - 8.6 6.6 9.6 10 6.3 6.7 1.1 1 0 0 1 1 1 0 AAA domain AUX_IAA PF02309.11 CDI88070.1 - 9.8 5.8 15.3 12 5.5 10.6 1.2 1 0 0 1 1 1 0 AUX/IAA family Bap31 PF05529.7 CDI88071.1 - 0.0072 15.7 8.3 0.0078 15.6 5.7 1.0 1 0 0 1 1 1 1 B-cell receptor-associated protein 31-like FimP PF09766.4 CDI88071.1 - 0.013 14.6 20.5 0.015 14.4 14.2 1.0 1 0 0 1 1 1 0 Fms-interacting protein DUF1980 PF09323.5 CDI88071.1 - 0.031 14.0 8.3 0.034 13.9 5.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) BLVR PF06375.6 CDI88071.1 - 0.035 13.9 8.8 0.04 13.7 6.1 1.0 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) CBP4 PF07960.6 CDI88071.1 - 0.043 13.4 12.6 0.053 13.1 8.7 1.3 1 0 0 1 1 1 0 CBP4 DUF3260 PF11658.3 CDI88071.1 - 0.098 10.7 7.7 0.11 10.6 5.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3260) MRF_C2 PF13888.1 CDI88071.1 - 0.13 12.0 6.7 0.16 11.8 4.6 1.1 1 0 0 1 1 1 0 Myelin gene regulatory factor C-terminal domain 2 DUF3276 PF11680.3 CDI88071.1 - 0.2 11.4 6.6 0.23 11.2 4.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3276) EIIBC-GUT_N PF03612.9 CDI88071.1 - 0.21 11.1 8.4 0.24 11.0 5.8 1.0 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Ycf1 PF05758.7 CDI88071.1 - 0.23 9.1 12.2 0.24 9.0 8.4 1.0 1 0 0 1 1 1 0 Ycf1 7tm_2 PF00002.19 CDI88071.1 - 0.3 10.1 3.0 0.36 9.8 2.1 1.3 1 1 0 1 1 1 0 7 transmembrane receptor (Secretin family) DUF788 PF05620.6 CDI88071.1 - 0.38 10.6 8.2 0.42 10.4 5.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF788) FAM176 PF14851.1 CDI88071.1 - 0.38 10.4 3.8 0.37 10.4 2.7 1.1 1 0 0 1 1 1 0 FAM176 family Spt20 PF12090.3 CDI88071.1 - 0.42 9.9 14.1 0.49 9.7 9.8 1.2 1 0 0 1 1 1 0 Spt20 family Peroxin-13_N PF04088.8 CDI88071.1 - 0.57 10.1 4.7 0.62 10.0 3.2 1.1 1 0 0 1 1 1 0 Peroxin 13, N-terminal region DDHD PF02862.12 CDI88071.1 - 0.61 9.8 7.4 0.59 9.8 5.1 1.1 1 0 0 1 1 1 0 DDHD domain Serinc PF03348.10 CDI88071.1 - 0.63 8.6 8.3 0.62 8.7 5.7 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) Gastrin PF00918.12 CDI88071.1 - 0.63 10.8 12.5 0.62 10.8 8.7 1.1 1 0 0 1 1 1 0 Gastrin/cholecystokinin family RNA_pol_Rpb1_2 PF00623.15 CDI88071.1 - 0.66 9.9 7.7 0.63 9.9 5.3 1.0 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 2 OATP PF03137.15 CDI88071.1 - 0.74 7.7 6.7 0.78 7.7 4.6 1.0 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Folate_carrier PF01770.13 CDI88071.1 - 0.76 8.2 8.1 0.81 8.1 5.6 1.0 1 0 0 1 1 1 0 Reduced folate carrier DUF912 PF06024.7 CDI88071.1 - 0.77 9.8 7.6 0.91 9.6 5.3 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Gti1_Pac2 PF09729.4 CDI88071.1 - 0.79 9.5 7.5 0.87 9.4 5.2 1.1 1 0 0 1 1 1 0 Gti1/Pac2 family Pal1 PF08316.6 CDI88071.1 - 0.82 10.1 4.4 0.85 10.0 3.0 1.0 1 0 0 1 1 1 0 Pal1 cell morphology protein DUF4407 PF14362.1 CDI88071.1 - 1.1 8.0 14.9 1.2 8.0 10.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Ctr PF04145.10 CDI88071.1 - 1.2 9.1 4.1 1.3 9.1 2.8 1.1 1 0 0 1 1 1 0 Ctr copper transporter family DUF775 PF05603.7 CDI88071.1 - 1.3 8.5 14.9 1.5 8.2 10.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF775) VKG_Carbox PF05090.9 CDI88071.1 - 1.4 7.7 4.9 1.5 7.5 3.4 1.0 1 0 0 1 1 1 0 Vitamin K-dependent gamma-carboxylase zf-DHHC PF01529.15 CDI88071.1 - 1.4 8.2 5.2 1.7 8.0 3.6 1.2 1 0 0 1 1 1 0 DHHC palmitoyltransferase Dala_Dala_lig_N PF01820.16 CDI88071.1 - 1.5 9.1 6.4 1.7 8.9 4.4 1.1 1 0 0 1 1 1 0 D-ala D-ala ligase N-terminus AIF_C PF14721.1 CDI88071.1 - 1.7 8.9 8.4 1.8 8.8 5.8 1.1 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term GOLD_2 PF13897.1 CDI88071.1 - 1.9 8.7 4.0 2.1 8.5 2.8 1.1 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking eIF_4EBP PF05456.6 CDI88071.1 - 2.2 7.9 8.6 2.8 7.6 6.0 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) FPN1 PF06963.7 CDI88071.1 - 2.3 6.4 6.0 2.6 6.3 4.2 1.0 1 0 0 1 1 1 0 Ferroportin1 (FPN1) Peptidase_S49_N PF08496.5 CDI88071.1 - 2.6 7.8 10.8 2.8 7.7 7.5 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF2215 PF10225.4 CDI88071.1 - 2.6 7.4 7.7 2.8 7.3 5.3 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) Band_3_cyto PF07565.8 CDI88071.1 - 2.8 7.3 12.4 2.8 7.3 8.6 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Glyco_transf_6 PF03414.8 CDI88071.1 - 2.9 6.2 9.0 3.2 6.1 6.2 1.0 1 0 0 1 1 1 0 Glycosyltransferase family 6 DUF897 PF05982.7 CDI88071.1 - 3 6.5 4.9 3.2 6.4 3.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF897) Kei1 PF08552.6 CDI88071.1 - 3.1 7.4 6.3 3.3 7.3 4.4 1.2 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 FMN_dh PF01070.13 CDI88071.1 - 3.1 6.5 5.8 3.5 6.3 4.1 1.0 1 0 0 1 1 1 0 FMN-dependent dehydrogenase DUF853 PF05872.7 CDI88071.1 - 3.2 6.0 10.4 3.2 6.0 7.2 1.0 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) Glt_symporter PF03616.9 CDI88071.1 - 3.3 6.0 4.9 3.5 6.0 3.4 1.2 1 0 0 1 1 1 0 Sodium/glutamate symporter DUF3371 PF11851.3 CDI88071.1 - 3.3 8.3 19.6 4.4 7.9 13.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3371) Suf PF05843.9 CDI88071.1 - 3.4 7.3 18.0 3.7 7.2 12.5 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) SID-1_RNA_chan PF13965.1 CDI88071.1 - 3.4 5.7 8.7 3.5 5.6 6.0 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Folliculin PF11704.3 CDI88071.1 - 3.4 7.2 10.1 3.9 7.0 7.0 1.1 1 0 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport Rpp20 PF12328.3 CDI88071.1 - 3.4 7.2 9.6 3.9 7.1 6.7 1.1 1 0 0 1 1 1 0 Rpp20 subunit of nuclear RNase MRP and P DUF106 PF01956.11 CDI88071.1 - 3.5 7.1 13.8 3.9 6.9 9.6 1.1 1 0 0 1 1 1 0 Integral membrane protein DUF106 PAT1 PF09770.4 CDI88071.1 - 3.5 5.7 30.2 3.6 5.7 20.9 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF4557 PF15101.1 CDI88071.1 - 3.7 7.3 20.9 3.8 7.3 14.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) Pneumo_M2 PF07380.6 CDI88071.1 - 3.8 7.5 9.3 7.7 6.5 6.4 1.5 1 1 0 1 1 1 0 Pneumovirus M2 protein Peptidase_S15 PF02129.13 CDI88071.1 - 3.9 6.8 9.4 4.2 6.6 6.5 1.0 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) GerA PF03323.8 CDI88071.1 - 4.2 5.4 8.4 4.6 5.2 5.8 1.0 1 0 0 1 1 1 0 Bacillus/Clostridium GerA spore germination protein DUF4199 PF13858.1 CDI88071.1 - 4.2 7.2 10.7 4.6 7.1 7.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) Neur_chan_memb PF02932.11 CDI88071.1 - 4.4 7.1 8.4 4.7 7.0 5.9 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region LpxB PF02684.10 CDI88071.1 - 4.5 5.8 12.2 4.5 5.7 8.4 1.0 1 0 0 1 1 1 0 Lipid-A-disaccharide synthetase Mem_trans PF03547.13 CDI88071.1 - 4.7 5.3 7.7 4.9 5.3 5.3 1.0 1 0 0 1 1 1 0 Membrane transport protein UPF0560 PF10577.4 CDI88071.1 - 5.1 5.2 18.0 4.6 5.3 12.5 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 MFS_Mycoplasma PF07672.8 CDI88071.1 - 5.1 6.1 6.2 6.1 5.9 4.3 1.1 1 0 0 1 1 1 0 Mycoplasma MFS transporter DUF2232 PF09991.4 CDI88071.1 - 5.9 5.8 12.8 6.3 5.6 8.9 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) Lipase_GDSL_3 PF14606.1 CDI88071.1 - 6.2 6.5 7.4 6.1 6.5 5.1 1.0 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family TMEM51 PF15345.1 CDI88071.1 - 6.4 6.4 12.8 6.5 6.3 8.9 1.1 1 0 0 1 1 1 0 Transmembrane protein 51 PEX11 PF05648.9 CDI88071.1 - 6.8 5.8 8.7 7.3 5.7 6.1 1.1 1 0 0 1 1 1 0 Peroxisomal biogenesis factor 11 (PEX11) Endonuc_Holl PF10107.4 CDI88071.1 - 6.8 6.3 14.7 7.9 6.1 10.2 1.0 1 0 0 1 1 1 0 Endonuclease related to archaeal Holliday junction resolvase RED_N PF07808.8 CDI88071.1 - 6.9 5.8 21.9 8.2 5.5 15.2 1.2 1 0 0 1 1 1 0 RED-like protein N-terminal region Peptidase_U57 PF05582.7 CDI88071.1 - 7 5.5 9.7 7.1 5.4 6.7 1.0 1 0 0 1 1 1 0 YabG peptidase U57 Hom_end_hint PF05203.11 CDI88071.1 - 7 6.3 9.1 7.3 6.2 6.3 1.0 1 0 0 1 1 1 0 Hom_end-associated Hint ATAD4 PF15321.1 CDI88071.1 - 7.5 7.6 10.6 9.1 7.3 7.4 1.2 1 0 0 1 1 1 0 ATPase family AAA domain containing 4 ABC2_membrane_2 PF12679.2 CDI88071.1 - 8.2 5.1 5.8 8.4 5.1 4.0 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF1764 PF08576.5 CDI88071.1 - 8.3 7.2 14.2 8.8 7.1 9.9 1.1 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) DUF3464 PF11947.3 CDI88071.1 - 8.4 5.8 8.5 9.5 5.6 5.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) FliP PF00813.15 CDI88071.1 - 8.9 5.9 7.3 9.5 5.8 5.1 1.1 1 0 0 1 1 1 0 FliP family CRF1 PF10380.4 CDI88071.1 - 9 6.6 8.6 9.5 6.5 6.0 1.1 1 0 0 1 1 1 0 Transcription factor CRF1 Pex14_N PF04695.8 CDI88071.1 - 9.8 6.2 18.7 11 6.0 13.0 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF945 PF06097.6 CDI88071.1 - 10 4.8 19.4 11 4.7 13.5 1.0 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF945) SAGA-Tad1 PF12767.2 CDI88072.1 - 0.01 15.4 17.2 0.013 15.1 11.9 1.2 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit Suf PF05843.9 CDI88072.1 - 0.13 11.9 20.5 0.16 11.7 14.2 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF3843 PF12954.2 CDI88072.1 - 0.84 8.6 6.3 1 8.3 4.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3843) PAT1 PF09770.4 CDI88072.1 - 0.92 7.6 50.4 1 7.5 34.9 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Band_3_cyto PF07565.8 CDI88072.1 - 1.5 8.2 10.8 1.9 7.9 7.5 1.4 1 0 0 1 1 1 0 Band 3 cytoplasmic domain DUF4175 PF13779.1 CDI88072.1 - 3.6 5.1 47.3 4.9 4.7 32.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) DUF45 PF01863.12 CDI88072.1 - 6.7 6.4 10.6 8.5 6.1 7.4 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF45 Hid1 PF12722.2 CDI88072.1 - 7.4 4.1 14.1 7.9 4.0 9.8 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein PLRV_ORF5 PF01690.12 CDI88072.1 - 8.5 5.3 15.9 11 5.0 11.0 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Ndc1_Nup PF09531.5 CDI88072.1 - 8.7 4.6 14.2 10 4.3 9.9 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup ketoacyl-synt PF00109.21 CDI88073.1 - 6.3e-47 160.1 0.0 7.2e-47 159.9 0.0 1.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain F_actin_cap_B PF01115.12 CDI88074.1 - 0.052 12.7 0.1 0.064 12.4 0.1 1.1 1 0 0 1 1 1 0 F-actin capping protein, beta subunit Insulin PF00049.13 CDI88074.1 - 0.76 10.5 4.2 0.73 10.6 2.4 1.8 1 1 0 1 1 1 0 Insulin/IGF/Relaxin family Med15 PF09606.5 CDI88075.1 - 0.0026 16.0 70.5 0.003 15.8 48.9 1.2 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal HCV_NS4b PF01001.14 CDI88075.1 - 0.0081 15.5 0.0 0.014 14.8 0.0 1.3 1 0 0 1 1 1 1 Hepatitis C virus non-structural protein NS4b PAT1 PF09770.4 CDI88075.1 - 0.99 7.5 60.2 1.2 7.2 41.7 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 LMBR1 PF04791.11 CDI88075.1 - 1.5 7.3 3.9 1.9 6.9 2.7 1.4 1 1 0 1 1 1 0 LMBR1-like membrane protein Rax2 PF12768.2 CDI88076.1 - 0.0029 16.8 0.6 0.0035 16.6 0.4 1.1 1 0 0 1 1 1 1 Cortical protein marker for cell polarity Trp_oprn_chp PF09534.5 CDI88076.1 - 0.0069 16.0 3.4 0.0085 15.7 2.4 1.1 1 0 0 1 1 1 1 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF3357 PF11837.3 CDI88076.1 - 0.0073 16.1 2.7 0.5 10.2 0.4 2.2 1 1 1 2 2 2 2 Domain of unknown function (DUF3357) DUF4366 PF14283.1 CDI88076.1 - 0.009 15.4 0.6 0.012 15.0 0.4 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4366) DUF2489 PF10675.4 CDI88076.1 - 0.016 14.9 25.1 0.26 10.9 3.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2489) BatD PF13584.1 CDI88076.1 - 0.033 12.7 6.9 0.039 12.5 4.8 1.0 1 0 0 1 1 1 0 Oxygen tolerance FA_desaturase PF00487.19 CDI88076.1 - 0.036 13.4 0.8 0.043 13.2 0.6 1.1 1 0 0 1 1 1 0 Fatty acid desaturase G-alpha PF00503.15 CDI88076.1 - 0.095 11.3 5.8 0.11 11.1 4.0 1.0 1 0 0 1 1 1 0 G-protein alpha subunit PSK PF06404.7 CDI88076.1 - 0.12 13.1 9.0 2.1 9.1 1.2 2.1 2 0 0 2 2 2 0 Phytosulfokine precursor protein (PSK) Adaptin_binding PF10199.4 CDI88076.1 - 0.17 12.1 11.7 0.21 11.8 8.1 1.1 1 0 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 CcmH PF03918.9 CDI88076.1 - 0.19 10.7 9.4 0.13 11.3 1.0 2.2 1 1 1 2 2 2 0 Cytochrome C biogenesis protein Herpes_UL87 PF03043.9 CDI88076.1 - 0.22 9.8 8.8 0.24 9.7 6.1 1.0 1 0 0 1 1 1 0 Herpesvirus UL87 family 7tm_1 PF00001.16 CDI88076.1 - 0.23 10.5 8.8 0.52 9.3 6.1 1.5 1 1 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) DDHD PF02862.12 CDI88076.1 - 0.24 11.1 7.3 0.3 10.8 5.1 1.1 1 0 0 1 1 1 0 DDHD domain Cytochrom_B_N PF00033.14 CDI88076.1 - 0.25 10.6 1.9 0.91 8.8 0.3 1.8 1 1 1 2 2 2 0 Cytochrome b(N-terminal)/b6/petB Zip PF02535.17 CDI88076.1 - 0.26 10.2 10.5 0.43 9.5 7.3 1.3 1 1 0 1 1 1 0 ZIP Zinc transporter RskA PF10099.4 CDI88076.1 - 0.38 10.4 15.4 0.84 9.3 10.8 1.5 1 1 0 1 1 1 0 Anti-sigma-K factor rskA EphA2_TM PF14575.1 CDI88076.1 - 0.41 11.0 14.4 0.84 10.0 0.9 2.5 1 1 2 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain TRM13 PF05206.9 CDI88076.1 - 0.45 9.7 10.8 0.57 9.3 1.7 2.0 2 0 0 2 2 2 0 Methyltransferase TRM13 DUF3824 PF12868.2 CDI88076.1 - 0.95 10.3 4.0 4.5 8.2 0.0 2.0 2 0 0 2 2 2 0 Domain of unknwon function (DUF3824) GRP PF07172.6 CDI88076.1 - 0.96 9.9 3.4 18 5.8 0.1 2.2 2 0 0 2 2 2 0 Glycine rich protein family Oleosin PF01277.12 CDI88076.1 - 0.97 9.0 10.2 0.72 9.4 0.9 2.1 2 0 0 2 2 2 0 Oleosin DUF3899 PF13038.1 CDI88076.1 - 1.1 9.4 4.4 2.2 8.5 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF3899) DUF3915 PF13054.1 CDI88076.1 - 1.3 9.0 5.2 0.6 10.0 0.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3915) OPA3 PF07047.7 CDI88076.1 - 1.3 8.8 10.6 5 6.9 0.2 2.1 2 0 0 2 2 2 0 Optic atrophy 3 protein (OPA3) zf-DHHC PF01529.15 CDI88076.1 - 1.4 8.3 7.9 4.8 6.5 1.1 2.1 2 0 0 2 2 2 0 DHHC palmitoyltransferase DUF2140 PF09911.4 CDI88076.1 - 1.8 7.7 8.1 2.7 7.1 1.4 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2140) DUF2722 PF10846.3 CDI88076.1 - 2.3 7.1 20.6 1.7 7.5 2.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) DUF788 PF05620.6 CDI88076.1 - 2.4 7.9 16.0 4.4 7.1 3.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF788) eIF_4EBP PF05456.6 CDI88076.1 - 2.4 7.8 9.0 4.6 6.9 0.7 2.1 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) FAM60A PF15396.1 CDI88076.1 - 2.7 7.6 12.1 3.4 7.3 8.4 1.1 1 0 0 1 1 1 0 Protein Family FAM60A FimP PF09766.4 CDI88076.1 - 2.7 6.9 23.7 0.37 9.7 4.0 2.0 2 0 0 2 2 2 0 Fms-interacting protein Conotoxin PF02950.12 CDI88076.1 - 3.1 8.6 17.4 0.17 12.7 2.5 2.4 1 1 1 2 2 2 0 Conotoxin HCO3_cotransp PF00955.16 CDI88076.1 - 4.1 5.9 5.5 4.6 5.7 3.8 1.0 1 0 0 1 1 1 0 HCO3- transporter family RNA_pol_Rpb1_5 PF04998.12 CDI88076.1 - 4.3 6.5 7.2 4.9 6.3 5.0 1.1 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 TFIIA PF03153.8 CDI88076.1 - 4.5 7.0 26.2 5.6 6.7 18.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4207 PF13904.1 CDI88076.1 - 4.7 6.5 30.5 3.3 7.0 6.6 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4207) GPI2 PF06432.6 CDI88076.1 - 5.2 6.3 7.0 1.2 8.4 0.6 1.9 1 1 1 2 2 2 0 Phosphatidylinositol N-acetylglucosaminyltransferase TerC PF03741.11 CDI88076.1 - 6 6.2 7.4 9.7 5.5 1.1 2.1 1 1 1 2 2 2 0 Integral membrane protein TerC family DUF2512 PF10710.4 CDI88076.1 - 6.2 6.2 5.6 6.8 6.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2512) DUF1764 PF08576.5 CDI88076.1 - 7.7 7.3 13.8 12 6.7 1.8 2.1 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF1764) CT47 PF15623.1 CDI88077.1 - 3.4 7.3 23.1 5.6 6.6 16.0 1.3 1 0 0 1 1 1 0 Cancer/testis gene family 47 DUF2407_C PF13373.1 CDI88078.1 - 0.03 14.2 14.0 0.035 14.0 9.7 1.1 1 0 0 1 1 1 0 DUF2407 C-terminal domain Herpes_DNAp_acc PF04929.7 CDI88078.1 - 0.084 11.8 11.6 0.1 11.5 8.0 1.0 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Spore_coat_CotO PF14153.1 CDI88078.1 - 0.12 11.8 25.3 0.15 11.5 17.6 1.1 1 0 0 1 1 1 0 Spore coat protein CotO YqzL PF14006.1 CDI88078.1 - 0.18 12.0 0.6 0.18 12.0 0.4 3.2 1 1 1 2 2 1 0 YqzL-like protein CPSF100_C PF13299.1 CDI88078.1 - 0.27 11.4 13.9 0.31 11.2 9.7 1.1 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal TCP PF03634.8 CDI88078.1 - 0.38 11.1 15.5 0.51 10.7 10.8 1.1 1 0 0 1 1 1 0 TCP family transcription factor Hid1 PF12722.2 CDI88078.1 - 0.57 7.8 19.2 0.6 7.7 13.3 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Autophagy_N PF03986.8 CDI88078.1 - 0.62 9.8 15.1 0.73 9.5 10.4 1.1 1 0 0 1 1 1 0 Autophagocytosis associated protein (Atg3), N-terminal domain DUF4080 PF13311.1 CDI88078.1 - 0.64 10.0 11.8 0.68 9.9 8.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4080) DUF2347 PF09804.4 CDI88078.1 - 0.65 9.2 16.2 0.7 9.1 11.3 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2347) eIF-3_zeta PF05091.7 CDI88078.1 - 0.73 8.3 21.3 0.82 8.2 14.8 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DHHW PF14286.1 CDI88078.1 - 1.1 8.5 13.1 1.3 8.2 9.1 1.1 1 0 0 1 1 1 0 DHHW protein MRP-S31 PF15433.1 CDI88078.1 - 1.1 8.6 25.7 1.2 8.4 17.8 1.0 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 DUF4175 PF13779.1 CDI88078.1 - 1.3 6.6 55.7 1.5 6.3 38.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Ycf1 PF05758.7 CDI88078.1 - 1.7 6.2 19.6 1.7 6.2 13.6 1.0 1 0 0 1 1 1 0 Ycf1 DUF4220 PF13968.1 CDI88078.1 - 2 7.4 10.5 2.5 7.1 7.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4220) Zip PF02535.17 CDI88078.1 - 2.1 7.2 5.6 2.4 7.0 3.9 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter FAM60A PF15396.1 CDI88078.1 - 2.2 7.9 15.4 2.4 7.8 10.7 1.1 1 0 0 1 1 1 0 Protein Family FAM60A FLO_LFY PF01698.11 CDI88078.1 - 2.3 6.9 19.1 2.7 6.7 13.2 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein Neur_chan_memb PF02932.11 CDI88078.1 - 2.3 8.0 13.5 2.8 7.7 9.3 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Band_3_cyto PF07565.8 CDI88078.1 - 2.5 7.5 23.2 3 7.2 16.1 1.0 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Cellulose_synt PF03552.9 CDI88078.1 - 2.6 6.2 8.8 2.5 6.2 6.1 1.0 1 0 0 1 1 1 0 Cellulose synthase HCO3_cotransp PF00955.16 CDI88078.1 - 3.1 6.3 6.8 3.3 6.2 4.7 1.0 1 0 0 1 1 1 0 HCO3- transporter family PAT1 PF09770.4 CDI88078.1 - 3.2 5.8 47.9 3.6 5.7 33.2 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF2828 PF11443.3 CDI88078.1 - 3.3 5.8 13.5 3.7 5.6 9.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Herpes_UL87 PF03043.9 CDI88078.1 - 3.3 5.9 11.0 3.6 5.8 7.6 1.0 1 0 0 1 1 1 0 Herpesvirus UL87 family CAF-1_p150 PF11600.3 CDI88078.1 - 3.5 6.9 26.5 4.4 6.6 18.4 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF2813 PF11398.3 CDI88078.1 - 3.7 6.5 25.2 4.2 6.3 17.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2813) RR_TM4-6 PF06459.7 CDI88078.1 - 4.1 7.2 20.5 5.1 6.9 14.2 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 PMSI1 PF15322.1 CDI88078.1 - 4.1 6.3 11.7 4.5 6.2 8.1 1.1 1 0 0 1 1 1 0 Protein missing in infertile sperm 1, putative RNA_pol_Rpb1_5 PF04998.12 CDI88078.1 - 4.1 6.5 10.8 4.4 6.4 7.5 1.1 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 DUF2076 PF09849.4 CDI88078.1 - 4.1 7.3 34.9 4.6 7.2 24.2 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) DUF913 PF06025.7 CDI88078.1 - 4.9 5.8 10.6 6.8 5.3 7.4 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) BTV_NS2 PF04514.7 CDI88078.1 - 5.4 5.7 16.3 6 5.6 11.3 1.0 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 DUF4045 PF13254.1 CDI88078.1 - 5.4 6.1 16.8 6.2 5.9 11.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Radical_SAM_N PF08497.5 CDI88078.1 - 5.8 5.7 15.0 6.5 5.5 10.4 1.0 1 0 0 1 1 1 0 Radical SAM N-terminal AUX_IAA PF02309.11 CDI88078.1 - 6 6.5 16.4 7.2 6.2 11.3 1.1 1 0 0 1 1 1 0 AUX/IAA family AAA_11 PF13086.1 CDI88078.1 - 6.8 6.1 18.6 8.2 5.9 12.9 1.1 1 0 0 1 1 1 0 AAA domain DUF2126 PF09899.4 CDI88078.1 - 7.4 4.4 14.2 8.2 4.3 9.9 1.1 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) Myco_haema PF05692.7 CDI88078.1 - 7.9 5.0 17.5 0.4 9.3 7.4 1.8 1 1 1 2 2 2 0 Mycoplasma haemagglutinin Suf PF05843.9 CDI88079.1 - 0.00025 20.9 12.8 0.00029 20.6 8.8 1.3 1 0 0 1 1 1 1 Suppressor of forked protein (Suf) Eapp_C PF10238.4 CDI88079.1 - 0.007 16.2 8.9 0.01 15.7 6.2 1.2 1 0 0 1 1 1 1 E2F-associated phosphoprotein SR-25 PF10500.4 CDI88079.1 - 0.009 15.5 10.5 0.011 15.2 7.3 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein DUF605 PF04652.11 CDI88079.1 - 0.01 15.2 21.6 0.012 15.0 15.0 1.0 1 0 0 1 1 1 0 Vta1 like zf-DHHC PF01529.15 CDI88079.1 - 0.016 14.6 3.5 0.017 14.5 2.4 1.2 1 0 0 1 1 1 0 DHHC palmitoyltransferase DUF912 PF06024.7 CDI88079.1 - 0.032 14.2 6.1 0.07 13.1 4.2 1.6 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) CRT10 PF08728.5 CDI88079.1 - 0.036 12.0 4.7 0.043 11.8 3.2 1.0 1 0 0 1 1 1 0 CRT10 SAGA-Tad1 PF12767.2 CDI88079.1 - 0.037 13.7 17.4 0.04 13.5 12.1 1.1 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit eIF-3_zeta PF05091.7 CDI88079.1 - 0.037 12.6 12.9 0.037 12.6 9.0 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) FAM60A PF15396.1 CDI88079.1 - 0.038 13.7 7.0 0.046 13.4 4.8 1.2 1 0 0 1 1 1 0 Protein Family FAM60A MRP-S31 PF15433.1 CDI88079.1 - 0.039 13.3 12.0 0.043 13.2 8.3 1.1 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 Methyltransf_12 PF08242.7 CDI88079.1 - 0.046 14.2 2.7 0.074 13.5 1.9 1.5 1 1 0 1 1 1 0 Methyltransferase domain Tim54 PF11711.3 CDI88079.1 - 0.047 12.2 4.6 0.049 12.2 3.2 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 FimP PF09766.4 CDI88079.1 - 0.057 12.4 23.7 0.07 12.1 16.4 1.1 1 0 0 1 1 1 0 Fms-interacting protein Presenilin PF01080.12 CDI88079.1 - 0.061 12.1 7.8 0.064 12.0 5.4 1.1 1 0 0 1 1 1 0 Presenilin DUF1390 PF07150.6 CDI88079.1 - 0.078 12.3 6.9 0.088 12.1 4.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1390) CDC45 PF02724.9 CDI88079.1 - 0.081 10.9 7.9 0.087 10.8 5.4 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF913 PF06025.7 CDI88079.1 - 0.081 11.6 7.2 0.091 11.5 5.0 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) AUX_IAA PF02309.11 CDI88079.1 - 0.098 12.3 10.4 0.11 12.2 7.2 1.1 1 0 0 1 1 1 0 AUX/IAA family HemX PF04375.9 CDI88079.1 - 0.12 10.9 24.1 0.15 10.6 16.7 1.1 1 0 0 1 1 1 0 HemX Dala_Dala_lig_N PF01820.16 CDI88079.1 - 0.13 12.6 3.4 0.17 12.2 2.4 1.3 1 0 0 1 1 1 0 D-ala D-ala ligase N-terminus Thioredoxin_9 PF14595.1 CDI88079.1 - 0.13 11.7 7.3 0.19 11.3 5.1 1.2 1 0 0 1 1 1 0 Thioredoxin DUF106 PF01956.11 CDI88079.1 - 0.14 11.7 9.0 0.17 11.4 6.2 1.1 1 0 0 1 1 1 0 Integral membrane protein DUF106 Het-C PF07217.6 CDI88079.1 - 0.16 10.1 6.8 0.16 10.0 4.7 1.1 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C UPF0560 PF10577.4 CDI88079.1 - 0.17 10.1 19.0 0.18 10.0 13.2 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 SprA-related PF12118.3 CDI88079.1 - 0.17 11.1 40.1 0.22 10.7 27.8 1.1 1 0 0 1 1 1 0 SprA-related family OATP PF03137.15 CDI88079.1 - 0.18 9.8 10.0 0.21 9.5 6.9 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family PAT1 PF09770.4 CDI88079.1 - 0.2 9.8 38.8 0.22 9.7 26.9 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Hom_end_hint PF05203.11 CDI88079.1 - 0.2 11.3 5.1 0.23 11.1 3.5 1.1 1 0 0 1 1 1 0 Hom_end-associated Hint Serinc PF03348.10 CDI88079.1 - 0.2 10.3 10.6 0.23 10.1 7.3 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) Folate_carrier PF01770.13 CDI88079.1 - 0.21 10.0 8.0 0.27 9.7 5.5 1.1 1 0 0 1 1 1 0 Reduced folate carrier Glt_symporter PF03616.9 CDI88079.1 - 0.22 10.0 4.2 0.28 9.6 2.9 1.2 1 0 0 1 1 1 0 Sodium/glutamate symporter DUF2828 PF11443.3 CDI88079.1 - 0.22 9.6 7.3 0.23 9.6 5.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) RR_TM4-6 PF06459.7 CDI88079.1 - 0.23 11.3 12.8 0.26 11.1 8.8 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Glyco_transf_15 PF01793.11 CDI88079.1 - 0.24 10.3 9.2 0.29 10.0 6.4 1.1 1 0 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase Bud13 PF09736.4 CDI88079.1 - 0.24 11.6 16.9 0.32 11.2 11.7 1.2 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex Spc7_N PF15402.1 CDI88079.1 - 0.26 9.2 14.9 0.29 9.1 10.4 1.1 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 DUF4175 PF13779.1 CDI88079.1 - 0.26 8.9 39.8 0.33 8.6 27.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) CDK5_activator PF03261.10 CDI88079.1 - 0.27 10.5 11.1 0.35 10.1 7.7 1.4 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein Peptidase_S15 PF02129.13 CDI88079.1 - 0.27 10.6 7.7 0.31 10.4 5.3 1.2 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Band_3_cyto PF07565.8 CDI88079.1 - 0.27 10.7 12.6 0.32 10.4 8.7 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain NARP1 PF12569.3 CDI88079.1 - 0.29 9.8 11.0 0.31 9.7 7.6 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DUF4557 PF15101.1 CDI88079.1 - 0.29 10.9 24.5 0.37 10.6 17.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) Gti1_Pac2 PF09729.4 CDI88079.1 - 0.3 10.9 7.3 0.37 10.6 5.0 1.3 1 0 0 1 1 1 0 Gti1/Pac2 family Plasmodium_Vir PF05795.6 CDI88079.1 - 0.33 10.0 1.7 0.33 10.1 1.2 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein RED_N PF07808.8 CDI88079.1 - 0.36 10.0 21.5 0.53 9.4 14.9 1.2 1 0 0 1 1 1 0 RED-like protein N-terminal region DUF853 PF05872.7 CDI88079.1 - 0.37 9.1 9.8 0.37 9.0 6.8 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) DUF1800 PF08811.6 CDI88079.1 - 0.39 9.5 16.4 0.42 9.4 11.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1800) Hamartin PF04388.7 CDI88079.1 - 0.39 9.3 13.2 0.43 9.1 9.1 1.0 1 0 0 1 1 1 0 Hamartin protein Peptidase_S49_N PF08496.5 CDI88079.1 - 0.4 10.4 9.8 0.57 9.9 6.8 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal APG6 PF04111.7 CDI88079.1 - 0.46 9.4 14.5 0.56 9.1 10.1 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 FAM176 PF14851.1 CDI88079.1 - 0.46 10.1 5.5 0.66 9.6 3.8 1.2 1 0 0 1 1 1 0 FAM176 family Baculo_PP31 PF05311.6 CDI88079.1 - 0.48 9.6 13.2 0.58 9.3 9.1 1.2 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) Gly_rich PF12810.2 CDI88079.1 - 0.52 9.8 6.6 0.74 9.3 4.6 1.3 1 0 0 1 1 1 0 Glycine rich protein SeqA PF03925.8 CDI88079.1 - 0.54 9.9 12.2 0.7 9.5 8.5 1.2 1 0 0 1 1 1 0 SeqA protein DUF4220 PF13968.1 CDI88079.1 - 0.56 9.2 3.6 0.54 9.2 2.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4220) Spore_coat_CotO PF14153.1 CDI88079.1 - 0.66 9.3 20.4 0.84 9.0 14.2 1.2 1 0 0 1 1 1 0 Spore coat protein CotO CPSF100_C PF13299.1 CDI88079.1 - 0.67 10.1 9.8 0.82 9.8 6.8 1.3 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal FLO_LFY PF01698.11 CDI88079.1 - 0.68 8.7 12.0 0.74 8.5 8.3 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein Corona_nucleoca PF00937.13 CDI88079.1 - 0.74 8.7 17.8 0.86 8.4 12.3 1.1 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein Shadoo PF14999.1 CDI88079.1 - 0.78 9.6 10.6 1.1 9.1 7.3 1.2 1 0 0 1 1 1 0 Shadow of prion protein, neuroprotective AAA_23 PF13476.1 CDI88079.1 - 0.78 10.0 16.9 0.92 9.7 11.7 1.1 1 0 0 1 1 1 0 AAA domain DUF775 PF05603.7 CDI88079.1 - 0.8 9.1 16.0 1.3 8.4 11.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF775) DUF2126 PF09899.4 CDI88079.1 - 0.82 7.6 10.6 0.97 7.3 7.3 1.0 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) PPP4R2 PF09184.6 CDI88079.1 - 0.84 9.1 10.5 0.91 9.0 7.3 1.1 1 0 0 1 1 1 0 PPP4R2 Neur_chan_memb PF02932.11 CDI88079.1 - 0.91 9.3 6.7 1 9.1 4.6 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Ndc1_Nup PF09531.5 CDI88079.1 - 0.93 7.8 10.7 0.9 7.8 7.4 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup TFIIA PF03153.8 CDI88079.1 - 0.97 9.2 30.7 1.1 9.0 21.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DHHW PF14286.1 CDI88079.1 - 0.99 8.6 11.0 1.1 8.4 7.7 1.1 1 0 0 1 1 1 0 DHHW protein XRCC4 PF06632.7 CDI88079.1 - 1.1 8.0 10.2 1 8.1 5.9 1.7 2 0 0 2 2 2 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 Ycf1 PF05758.7 CDI88079.1 - 1.4 6.5 12.9 1.6 6.3 8.9 1.0 1 0 0 1 1 1 0 Ycf1 TMEM51 PF15345.1 CDI88079.1 - 1.5 8.4 21.2 0.23 11.1 11.7 1.7 2 0 0 2 2 2 0 Transmembrane protein 51 DDHD PF02862.12 CDI88079.1 - 1.6 8.4 14.5 1.9 8.1 10.0 1.2 1 0 0 1 1 1 0 DDHD domain Paramyxo_ncap PF00973.14 CDI88079.1 - 1.7 7.2 8.7 1.8 7.1 6.1 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Nucleoside_tran PF01733.13 CDI88079.1 - 2.3 7.2 4.9 2.8 7.0 3.4 1.1 1 0 0 1 1 1 0 Nucleoside transporter DUF4199 PF13858.1 CDI88079.1 - 2.5 8.0 8.1 4.1 7.2 5.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) Cellulose_synt PF03552.9 CDI88079.1 - 2.5 6.2 5.0 2.6 6.2 3.5 1.0 1 0 0 1 1 1 0 Cellulose synthase Paf1 PF03985.8 CDI88079.1 - 2.6 6.6 17.4 3.1 6.4 12.1 1.1 1 0 0 1 1 1 0 Paf1 eIF_4EBP PF05456.6 CDI88079.1 - 3 7.5 12.5 4.6 6.9 8.6 1.4 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) DUF3043 PF11241.3 CDI88079.1 - 3 7.3 9.2 4.5 6.8 6.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) Sec62 PF03839.11 CDI88079.1 - 4 6.7 10.6 4.9 6.4 7.3 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 Peptidase_U57 PF05582.7 CDI88079.1 - 4 6.3 11.6 5.1 5.9 8.0 1.1 1 0 0 1 1 1 0 YabG peptidase U57 Bul1_N PF04425.7 CDI88079.1 - 4.5 5.7 13.4 5.3 5.4 9.3 1.1 1 0 0 1 1 1 0 Bul1 N terminus PBP_sp32 PF07222.7 CDI88079.1 - 4.7 6.3 16.4 5.4 6.1 11.4 1.2 1 0 0 1 1 1 0 Proacrosin binding protein sp32 GOLD_2 PF13897.1 CDI88079.1 - 4.8 7.4 6.7 8.5 6.6 4.7 1.4 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking Ribosomal_60s PF00428.14 CDI88079.1 - 5 7.5 12.4 10 6.5 8.6 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein Ribonuclease_3 PF00636.21 CDI88079.1 - 5.7 7.4 7.3 12 6.4 5.1 1.5 1 1 0 1 1 1 0 Ribonuclease III domain Peptidase_S64 PF08192.6 CDI88079.1 - 6.1 5.0 13.9 6.7 4.9 9.6 1.0 1 0 0 1 1 1 0 Peptidase family S64 Herpes_DNAp_acc PF04929.7 CDI88079.1 - 6.7 5.5 15.6 8.2 5.2 10.8 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Hid1 PF12722.2 CDI88079.1 - 7.9 4.0 16.9 9.1 3.8 11.7 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Pex14_N PF04695.8 CDI88079.1 - 8.9 6.3 33.7 1.5e+02 2.3 23.3 2.1 1 1 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Endonuc_Holl PF10107.4 CDI88079.1 - 9 5.9 14.1 13 5.4 9.8 1.2 1 0 0 1 1 1 0 Endonuclease related to archaeal Holliday junction resolvase DOR PF14839.1 CDI88079.1 - 9 5.9 21.2 12 5.6 14.7 1.2 1 0 0 1 1 1 0 DOR family SprA-related PF12118.3 CDI88080.1 - 0.064 12.5 57.8 0.075 12.3 40.1 1.0 1 0 0 1 1 1 0 SprA-related family DUF2232 PF09991.4 CDI88080.1 - 0.25 10.3 3.7 0.31 9.9 2.6 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) DUF4199 PF13858.1 CDI88080.1 - 0.38 10.6 6.3 0.68 9.8 4.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) BSP_II PF05432.6 CDI88080.1 - 0.93 8.7 18.2 1.2 8.3 12.6 1.1 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) DUF3439 PF11921.3 CDI88080.1 - 1.1 8.9 17.8 0.48 10.1 10.5 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF3439) DUF605 PF04652.11 CDI88080.1 - 1.2 8.4 46.3 1.5 8.1 32.1 1.0 1 0 0 1 1 1 0 Vta1 like PBP1_TM PF14812.1 CDI88080.1 - 1.6 9.1 9.3 0.66 10.3 0.9 2.2 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal TFIIA PF03153.8 CDI88080.1 - 2.3 8.0 53.8 2.9 7.7 37.3 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit MelC1 PF06236.6 CDI88080.1 - 4.1 7.4 12.7 1 9.3 6.4 1.6 2 0 0 2 2 2 0 Tyrosinase co-factor MelC1 RAP1 PF07218.6 CDI88080.1 - 4.4 5.2 16.9 4.9 5.1 11.7 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) RR_TM4-6 PF06459.7 CDI88080.1 - 4.9 6.9 23.6 7 6.4 16.4 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF2899 PF11449.3 CDI88080.1 - 6.6 5.8 8.0 8.1 5.5 5.6 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2899) DDRGK PF09756.4 CDI88080.1 - 6.7 6.0 21.9 1.6 8.0 9.8 2.0 2 0 0 2 2 2 0 DDRGK domain Utp14 PF04615.8 CDI88080.1 - 9 4.3 37.1 11 4.0 25.7 1.0 1 0 0 1 1 1 0 Utp14 protein Cwf_Cwc_15 PF04889.7 CDJ26837.1 - 0.0012 18.6 43.2 0.0033 17.1 15.1 3.7 3 0 0 3 3 3 2 Cwf15/Cwc15 cell cycle control protein N6_N4_Mtase PF01555.13 CDJ26837.1 - 0.0063 16.0 0.0 0.22 10.9 0.0 3.2 2 1 0 2 2 2 1 DNA methylase DUF1510 PF07423.6 CDJ26837.1 - 0.0093 15.3 21.4 0.0093 15.3 14.8 4.2 3 1 1 4 4 4 2 Protein of unknown function (DUF1510) DUF3742 PF12553.3 CDJ26837.1 - 7.1 7.1 0.0 7.1 7.1 0.0 4.4 6 0 0 6 6 6 0 Protein of unknown function (DUF3742) CDC45 PF02724.9 CDJ26838.1 - 0.53 8.2 31.1 0.63 8.0 21.5 1.0 1 0 0 1 1 1 0 CDC45-like protein Nop53 PF07767.6 CDJ26838.1 - 1.8 7.4 39.4 2.7 6.8 27.3 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) PRP1_N PF06424.7 CDJ26838.1 - 3.8 7.8 26.9 4.4 7.6 18.7 1.1 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal Nop14 PF04147.7 CDJ26838.1 - 4.6 5.0 44.4 5.6 4.7 30.7 1.0 1 0 0 1 1 1 0 Nop14-like family Suf PF05843.9 CDJ26838.1 - 6 6.5 18.5 6.7 6.3 12.9 1.0 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Zip PF02535.17 CDJ26839.1 - 0.00078 18.5 3.1 0.00093 18.2 2.1 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter Shadoo PF14999.1 CDJ26839.1 - 0.0015 18.3 3.4 0.0018 18.1 2.3 1.1 1 0 0 1 1 1 1 Shadow of prion protein, neuroprotective DUF4557 PF15101.1 CDJ26839.1 - 0.0037 17.1 6.1 0.004 17.0 4.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4557) DUF4231 PF14015.1 CDJ26839.1 - 0.0047 16.9 2.7 0.0061 16.5 1.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4231) Med15 PF09606.5 CDJ26839.1 - 0.0082 14.4 21.9 0.0089 14.2 15.2 1.0 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal RskA PF10099.4 CDJ26839.1 - 0.0083 15.8 10.0 0.01 15.6 7.0 1.1 1 0 0 1 1 1 1 Anti-sigma-K factor rskA CD20 PF04103.10 CDJ26839.1 - 0.009 15.9 1.2 0.009 15.9 0.8 1.9 2 0 0 2 2 2 1 CD20-like family FAM222A PF15258.1 CDJ26839.1 - 0.017 14.3 12.3 0.017 14.3 8.5 1.0 1 0 0 1 1 1 0 Protein family of FAM222A HemX PF04375.9 CDJ26839.1 - 0.018 13.6 15.0 0.021 13.4 10.4 1.0 1 0 0 1 1 1 0 HemX DUF4131 PF13567.1 CDJ26839.1 - 0.025 13.9 0.1 0.036 13.4 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) FHIPEP PF00771.15 CDJ26839.1 - 0.029 12.7 1.7 0.027 12.8 1.2 1.0 1 0 0 1 1 1 0 FHIPEP family Spt20 PF12090.3 CDJ26839.1 - 0.033 13.5 3.3 0.029 13.7 2.3 1.1 1 0 0 1 1 1 0 Spt20 family OATP PF03137.15 CDJ26839.1 - 0.047 11.7 1.1 0.062 11.3 0.8 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Claudin_2 PF13903.1 CDJ26839.1 - 0.092 12.4 7.0 0.14 11.8 4.8 1.4 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction DUF3792 PF12670.2 CDJ26839.1 - 0.11 12.3 0.3 0.13 12.1 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3792) EphA2_TM PF14575.1 CDJ26839.1 - 0.12 12.8 0.4 0.18 12.2 0.3 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain TMEM171 PF15471.1 CDJ26839.1 - 0.22 10.2 4.3 0.32 9.7 3.0 1.3 1 0 0 1 1 1 0 Transmembrane protein family 171 DUF2512 PF10710.4 CDJ26839.1 - 0.23 10.9 9.1 1.7 8.1 4.7 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2512) Suf PF05843.9 CDJ26839.1 - 0.32 10.6 7.3 0.31 10.7 5.1 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) KfrA_N PF11740.3 CDJ26839.1 - 0.34 11.3 27.8 0.43 11.0 19.2 1.0 1 0 0 1 1 1 0 Plasmid replication region DNA-binding N-term DUF3617 PF12276.3 CDJ26839.1 - 0.77 9.2 9.9 1.2 8.5 6.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3617) DUF2681 PF10883.3 CDJ26839.1 - 0.79 9.9 13.4 1 9.6 9.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) DUF3357 PF11837.3 CDJ26839.1 - 0.87 9.4 3.9 0.86 9.4 1.7 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF3357) MelC1 PF06236.6 CDJ26839.1 - 0.92 9.4 14.9 1.1 9.1 10.4 1.2 1 0 0 1 1 1 0 Tyrosinase co-factor MelC1 FimP PF09766.4 CDJ26839.1 - 1 8.3 15.6 1.3 8.0 10.8 1.0 1 0 0 1 1 1 0 Fms-interacting protein DUF1049 PF06305.6 CDJ26839.1 - 1 8.8 4.2 0.22 11.0 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) RIC3 PF15361.1 CDJ26839.1 - 1.1 9.4 8.4 1.3 9.1 5.8 1.2 1 0 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 DUF3450 PF11932.3 CDJ26839.1 - 1.1 8.4 17.6 1.5 8.0 12.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) MSP1_C PF07462.6 CDJ26839.1 - 1.2 7.4 4.7 1.3 7.3 3.2 1.1 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus DUF533 PF04391.7 CDJ26839.1 - 1.2 8.4 17.5 1.5 8.2 12.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF533) RR_TM4-6 PF06459.7 CDJ26839.1 - 1.4 8.7 11.8 1.8 8.3 8.2 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 LCE PF14672.1 CDJ26839.1 - 3 8.4 9.0 0.094 13.2 1.4 1.9 2 0 0 2 2 2 0 Late cornified envelope R_equi_Vir PF05526.6 CDJ26839.1 - 3.1 7.4 11.0 3.8 7.1 7.6 1.1 1 0 0 1 1 1 0 Rhodococcus equi virulence-associated protein ERF PF04404.7 CDJ26839.1 - 6.8 6.2 13.7 8.5 5.8 9.5 1.1 1 0 0 1 1 1 0 ERF superfamily CPSF73-100_C PF11718.3 CDJ26839.1 - 7.1 5.9 10.6 8.3 5.6 7.3 1.1 1 0 0 1 1 1 0 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term eIF3_subunit PF08597.5 CDJ26839.1 - 8.4 5.8 12.0 10 5.6 8.3 1.1 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit